transcript sample140 sample145 sample150 sample173 sample178 V3 V13 Protein.names Organism Gene.Ontology..biological.process. Gene.Ontology.IDs 1 XM_044313592.1 108 46 63 105 131 NA NA NA NA NA NA 2 XR_006395886.1 0 0 0 6 139 Q8WZA2 0 Rap guanine nucleotide exchange factor 4 (Exchange factor directly activated by cAMP 2) (Exchange protein directly activated by cAMP 2) (EPAC 2) (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) Homo sapiens (Human) adaptive immune response [GO:0002250]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; calcium-ion regulated exocytosis [GO:0017156]; G protein-coupled receptor signaling pathway [GO:0007186]; insulin secretion [GO:0030073]; positive regulation of GTPase activity [GO:0043547]; positive regulation of insulin secretion [GO:0032024]; Ras protein signal transduction [GO:0007265]; regulation of exocytosis [GO:0017157]; regulation of synaptic vesicle cycle [GO:0098693] GO:0002250; GO:0005085; GO:0005096; GO:0005829; GO:0005886; GO:0007186; GO:0007189; GO:0007265; GO:0016020; GO:0017156; GO:0017157; GO:0030073; GO:0030552; GO:0030674; GO:0031267; GO:0032024; GO:0043547; GO:0098686; GO:0098693 3 XM_029343024.2 467 337 362 570 1234 P16331 0 Phenylalanine-4-hydroxylase (PAH) (EC 1.14.16.1) (Phe-4-monooxygenase) Mus musculus (Mouse) L-phenylalanine catabolic process [GO:0006559]; L-phenylalanine metabolic process [GO:0006558]; protein hydroxylation [GO:0018126]; tyrosine biosynthetic process [GO:0006571]; tyrosine biosynthetic process, by oxidation of phenylalanine [GO:0019293] GO:0004505; GO:0005506; GO:0006558; GO:0006559; GO:0006571; GO:0016597; GO:0018126; GO:0019293; GO:0042802 4 XM_044327972.1 43 21 5 12 41 NA NA NA NA NA NA 5 XR_006392795.1 108 0 0 0 0 NA NA NA NA NA NA 6 XM_044315346.1 20 0 21 18 232 NA NA NA NA NA NA 7 XM_044309244.1 5 26 23 24 73 NA NA NA NA NA NA 8 XM_044326194.1 55 65 9 0 7 NA NA NA NA NA NA 9 XM_044314742.1 73 155 36 270 1 NA NA NA NA NA NA 10 XR_006392295.1 120 30 11 38 43 NA NA NA NA NA NA 11 XM_029342319.2 0 0 2 0 18 NA NA NA NA NA NA 12 XM_029328980.2 42 0 0 0 0 NA NA NA NA NA NA 13 XM_029330965.1 2056 1394 1037 1456 1394 P48430 2.46e-48 Transcription factor SOX-2 (cSox2) (delta EF2a) Gallus gallus (Chicken) anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; forebrain development [GO:0030900]; inner ear development [GO:0048839]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; sensory organ precursor cell fate determination [GO:0016360] GO:0000122; GO:0000978; GO:0000981; GO:0005634; GO:0005737; GO:0006355; GO:0009653; GO:0016360; GO:0030154; GO:0030900; GO:0043565; GO:0045165; GO:0045665; GO:0045893; GO:0045944; GO:0048839 14 XM_029351061.2 0 0 0 0 186 Q61072 8.29e-65 Disintegrin and metalloproteinase domain-containing protein 9 (ADAM 9) (EC 3.4.24.-) (Meltrin-gamma) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) Mus musculus (Mouse) amyloid precursor protein catabolic process [GO:0042987]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell migration [GO:0016477]; cell-cell adhesion mediated by integrin [GO:0033631]; cell-matrix adhesion [GO:0007160]; cellular response to lipopolysaccharide [GO:0071222]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; monocyte activation [GO:0042117]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of macrophage fusion [GO:0034241]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of protein secretion [GO:0050714]; protein processing [GO:0016485]; response to calcium ion [GO:0051592]; response to glucocorticoid [GO:0051384]; response to hydrogen peroxide [GO:0042542]; response to manganese ion [GO:0010042]; response to tumor necrosis factor [GO:0034612]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0004222; GO:0005080; GO:0005178; GO:0005518; GO:0005615; GO:0005737; GO:0005886; GO:0006509; GO:0007155; GO:0007160; GO:0007179; GO:0008237; GO:0009897; GO:0009986; GO:0010042; GO:0016323; GO:0016477; GO:0016485; GO:0017124; GO:0030335; GO:0031293; GO:0033627; GO:0033630; GO:0033631; GO:0034241; GO:0034612; GO:0042117; GO:0042542; GO:0042987; GO:0043236; GO:0043406; GO:0046872; GO:0050714; GO:0051044; GO:0051384; GO:0051549; GO:0051592; GO:0071222; GO:1902945 15 XM_044327462.1 1179 703 547 890 769 NA NA NA NA NA NA 16 XM_029349959.2 694 212 303 561 105 F1M0Z1 1.36e-71 Triple functional domain protein (EC 2.7.11.1) (PTPRF-interacting protein) Rattus norvegicus (Rat) axon guidance [GO:0007411]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of fat cell differentiation [GO:0045599]; neuron projection morphogenesis [GO:0048812]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; protein phosphorylation [GO:0006468] GO:0004674; GO:0005085; GO:0005524; GO:0005737; GO:0006468; GO:0007411; GO:0019898; GO:0019899; GO:0042995; GO:0045599; GO:0048786; GO:0048812; GO:0050804; GO:0098685; GO:0098794; GO:0098978; GO:0099170; GO:0106310 17 XM_029349959.2 694 212 303 561 105 F1M0Z1 1.33e-53 Triple functional domain protein (EC 2.7.11.1) (PTPRF-interacting protein) Rattus norvegicus (Rat) axon guidance [GO:0007411]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of fat cell differentiation [GO:0045599]; neuron projection morphogenesis [GO:0048812]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; protein phosphorylation [GO:0006468] GO:0004674; GO:0005085; GO:0005524; GO:0005737; GO:0006468; GO:0007411; GO:0019898; GO:0019899; GO:0042995; GO:0045599; GO:0048786; GO:0048812; GO:0050804; GO:0098685; GO:0098794; GO:0098978; GO:0099170; GO:0106310 18 XM_044318636.1 5 4 7 13 25 P0CI65 1.27e-47 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 19 XM_044318636.1 5 4 7 13 25 P0CI65 2.61e-43 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 20 XM_044318636.1 5 4 7 13 25 P0CI65 1.37e-35 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 21 XR_006397562.1 8 3 26 89 28 NA NA NA NA NA NA 22 XM_044328392.1 1441 924 792 1079 1246 A0A0G2K047 0 Acyl-CoA synthetase short-chain family member 3, mitochondrial (EC 6.2.1.1) (Acetate--CoA ligase 3) (Acyl-CoA synthetase short-chain family member 3) (Propionate--CoA ligase) (EC 6.2.1.17) Rattus norvegicus (Rat) lipid metabolic process [GO:0006629] GO:0003987; GO:0005524; GO:0005759; GO:0006629; GO:0047760; GO:0050218 23 XM_044321678.1 36 114 137 86 38 NA NA NA NA NA NA 24 XM_029333713.2 38 31 18 72 55 Q9UBT6 0 DNA polymerase kappa (EC 2.7.7.7) (DINB protein) (DINP) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; error-prone translesion synthesis [GO:0042276]; nucleotide-excision repair, DNA gap filling [GO:0006297] GO:0003684; GO:0003887; GO:0005634; GO:0005654; GO:0006260; GO:0006281; GO:0006297; GO:0006974; GO:0016604; GO:0034644; GO:0042276; GO:0046872 25 XM_029352718.2 63 528 321 46 448 NA NA NA NA NA NA 26 XM_044318270.1 1239 797 942 3247 1382 Q9P2E3 1.89e-54 NFX1-type zinc finger-containing protein 1 Homo sapiens (Human) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 27 XM_044318270.1 1239 797 942 3247 1382 Q9P2E3 3e-29 NFX1-type zinc finger-containing protein 1 Homo sapiens (Human) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 28 XM_029345015.2 505 381 230 651 505 NA NA NA NA NA NA 29 XR_006396656.1 619 573 225 515 414 P39963 1.72e-89 G2/mitotic-specific cyclin-B3 Gallus gallus (Chicken) cell division [GO:0051301]; mitotic cell cycle phase transition [GO:0044772]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079] GO:0000079; GO:0000307; GO:0005634; GO:0005737; GO:0005813; GO:0016538; GO:0044772; GO:0051301 30 XM_044323596.1 11 0 22 0 0 NA NA NA NA NA NA 31 XM_044322370.1 18 14 0 1 220 NA NA NA NA NA NA 32 XM_029334675.2 740 505 500 774 894 Q8VHI3 3.3e-160 GDP-fucose protein O-fucosyltransferase 2 (EC 2.4.1.221) (Peptide-O-fucosyltransferase 2) (O-FucT-2) Mus musculus (Mouse) fucose metabolic process [GO:0006004]; fucosylation [GO:0036065]; mesoderm formation [GO:0001707]; positive regulation of protein folding [GO:1903334]; protein O-linked fucosylation [GO:0036066]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gene expression [GO:0010468]; regulation of secretion [GO:0051046] GO:0001707; GO:0005783; GO:0005794; GO:0006004; GO:0008417; GO:0010468; GO:0010717; GO:0036065; GO:0036066; GO:0046922; GO:0051046; GO:1903334 33 XM_029330060.2 61 50 72 33 0 Q14155 3.85e-152 Rho guanine nucleotide exchange factor 7 (Beta-Pix) (COOL-1) (PAK-interacting exchange factor beta) (p85) Homo sapiens (Human) ephrin receptor signaling pathway [GO:0048013]; focal adhesion assembly [GO:0048041]; Golgi organization [GO:0007030]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; negative regulation of microtubule nucleation [GO:1905833]; nervous system development [GO:0007399]; positive regulation of apoptotic process [GO:0043065]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of GTPase activity [GO:0043547]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of GTP binding [GO:1904424]; signal transduction [GO:0007165] GO:0001726; GO:0005085; GO:0005737; GO:0005813; GO:0005829; GO:0005925; GO:0005938; GO:0007030; GO:0007165; GO:0007399; GO:0010763; GO:0019901; GO:0030027; GO:0030032; GO:0032991; GO:0035556; GO:0043005; GO:0043015; GO:0043025; GO:0043065; GO:0043547; GO:0048013; GO:0048041; GO:0097431; GO:0098794; GO:1900026; GO:1904424; GO:1905833; GO:2000394 34 XM_044315445.1 2 140 2 26 0 NA NA NA NA NA NA 35 XM_044317870.1 20 10 0 7 17 NA NA NA NA NA NA 36 XR_006393279.1 25 25 37 44 83 NA NA NA NA NA NA 37 XM_044306976.1 406 320 303 330 404 A6PWV5 2.85e-67 AT-rich interactive domain-containing protein 3C (ARID domain-containing protein 3C) Mus musculus (Mouse) positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0003677; GO:0003682; GO:0005634; GO:0005737; GO:0006357; GO:0045121; GO:0045944 38 XM_044318031.1 65 20 45 62 47 NA NA NA NA NA NA 39 XR_006397318.1 201 82 12 126 163 NA NA NA NA NA NA 40 XM_029337337.2 123 108 30 0 68 O42115 2.32e-28 Aristaless-related homeobox protein (ARX) Danio rerio (Zebrafish) (Brachydanio rerio) enteric nervous system development [GO:0048484]; neuron development [GO:0048666]; pancreatic A cell development [GO:0003322]; regulation of transcription by RNA polymerase II [GO:0006357]; subthalamus development [GO:0021539]; telencephalon development [GO:0021537]; thalamus development [GO:0021794] GO:0000977; GO:0000981; GO:0003322; GO:0005634; GO:0006357; GO:0021537; GO:0021539; GO:0021794; GO:0048484; GO:0048666 41 XR_006395618.1 135 56 95 152 172 A0A3Q2HW92 6.28e-47 Major facilitator superfamily domain-containing protein 12 Equus caballus (Horse) carbohydrate transport [GO:0008643]; cysteine transmembrane transport [GO:1903712]; melanin biosynthetic process [GO:0042438]; negative regulation of melanin biosynthetic process [GO:0048022]; pigment metabolic process involved in pigmentation [GO:0043474] GO:0005764; GO:0005765; GO:0005770; GO:0008643; GO:0015293; GO:0033162; GO:0033229; GO:0042438; GO:0043474; GO:0048022; GO:1903712 42 XR_006395618.1 135 56 95 152 172 A0A3Q2HW92 6.28e-47 Major facilitator superfamily domain-containing protein 12 Equus caballus (Horse) carbohydrate transport [GO:0008643]; cysteine transmembrane transport [GO:1903712]; melanin biosynthetic process [GO:0042438]; negative regulation of melanin biosynthetic process [GO:0048022]; pigment metabolic process involved in pigmentation [GO:0043474] GO:0005764; GO:0005765; GO:0005770; GO:0008643; GO:0015293; GO:0033162; GO:0033229; GO:0042438; GO:0043474; GO:0048022; GO:1903712 43 XM_029332465.2 0 0 0 0 7 NA NA NA NA NA NA 44 XM_029331931.2 707 306 456 980 911 O46392 1.75e-52 Collagen alpha-2(I) chain (Alpha-2 type I collagen) Canis lupus familiaris (Dog) (Canis familiaris) NA GO:0005201; GO:0005576; GO:0005581; GO:0046872 45 XR_003826325.2 24 14 54 30 23 Q08431 9.72e-37 Lactadherin (Breast epithelial antigen BA46) (HMFG) (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (SED1) [Cleaved into: Lactadherin short form; Medin] Homo sapiens (Human) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005576; GO:0005615; GO:0005788; GO:0007155; GO:0007338; GO:0009897; GO:0016020; GO:0043277; GO:0062023; GO:0070062; GO:1903561 46 XM_044315417.1 277 0 281 0 0 NA NA NA NA NA NA 47 XR_003827962.2 185 20 116 125 248 O42449 2.54e-41 Type I iodothyronine deiodinase (EC 1.21.99.4) (5DI) (DIOI) (Type 1 DI) (Type-I 5'-deiodinase) Oreochromis niloticus (Nile tilapia) (Tilapia nilotica) hormone biosynthetic process [GO:0042446]; regulation of neural retina development [GO:0061074] GO:0004800; GO:0005789; GO:0042446; GO:0061074 48 XM_044311906.1 157 53 8 18 33 NA NA NA NA NA NA 49 XM_044323690.1 10 0 1 0 15 NA NA NA NA NA NA 50 XM_044317898.1 14 19 36 51 13 NA NA NA NA NA NA 51 XM_044325680.1 5 15 82 10 49 NA NA NA NA NA NA 52 XR_006396092.1 138 16 22 35 17 NA NA NA NA NA NA 53 XM_044315675.1 0 14 3 0 18 Q6DGA6 4.55e-36 Allantoicase (EC 3.5.3.4) (Allantoate amidinohydrolase) Danio rerio (Zebrafish) (Brachydanio rerio) allantoin catabolic process [GO:0000256]; purine nucleobase metabolic process [GO:0006144] GO:0000256; GO:0004037; GO:0006144 54 XM_044323687.1 2 1 0 24 0 Q09575 1.41e-29 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 55 XM_044316066.1 3 0 0 27 0 NA NA NA NA NA NA 56 XR_006397303.1 1 0 13 4 6 NA NA NA NA NA NA 57 XM_044322516.1 26 0 3 4 39 NA NA NA NA NA NA 58 XR_006392013.1 241 1 33 17 69 P14381 1.89e-32 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 59 XR_006392013.1 241 1 33 17 69 P14381 1.89e-32 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 60 XM_029335367.2 4109 4578 3797 4217 4187 Q66HG4 2.34e-93 Galactose mutarotase (EC 5.1.3.3) (Aldose 1-epimerase) Rattus norvegicus (Rat) carbohydrate metabolic process [GO:0005975]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]; glucose metabolic process [GO:0006006] GO:0004034; GO:0005737; GO:0005975; GO:0006006; GO:0006012; GO:0030246; GO:0033499 61 XM_029354142.2 207 12 0 28 364 A7RX69 1.02e-136 Metalloprotease TIKI homolog (EC 3.4.-.-) Nematostella vectensis (Starlet sea anemone) negative regulation of Wnt signaling pathway [GO:0030178]; proteolysis [GO:0006508] GO:0004222; GO:0006508; GO:0016020; GO:0030178; GO:0046872 62 XM_044314550.1 1 7 11 1 9 P16157 5.26e-66 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 63 XM_044314550.1 1 7 11 1 9 P16157 1.42e-54 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 64 XM_044314550.1 1 7 11 1 9 P16157 5.64e-47 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 65 XM_029338156.2 1230 944 1792 11350 3037 NA NA NA NA NA NA 66 XM_029350361.2 0 43 50 68 19 P09917 2.66e-85 Polyunsaturated fatty acid 5-lipoxygenase (EC 1.13.11.-) (Arachidonate 5-lipoxygenase) (5-LO) (5-lipoxygenase) (EC 1.13.11.34) Homo sapiens (Human) arachidonic acid metabolic process [GO:0019369]; dendritic cell migration [GO:0036336]; glucose homeostasis [GO:0042593]; hepoxilin biosynthetic process [GO:0051122]; humoral immune response [GO:0006959]; leukocyte chemotaxis involved in inflammatory response [GO:0002232]; leukocyte migration involved in inflammatory response [GO:0002523]; leukotriene A4 biosynthetic process [GO:1901753]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; leukotriene production involved in inflammatory response [GO:0002540]; linoleic acid metabolic process [GO:0043651]; lipid oxidation [GO:0034440]; lipoxin biosynthetic process [GO:2001301]; lipoxygenase pathway [GO:0019372]; long-chain fatty acid biosynthetic process [GO:0042759]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of inflammatory response [GO:0050728]; negative regulation of response to endoplasmic reticulum stress [GO:1903573]; negative regulation of sprouting angiogenesis [GO:1903671]; negative regulation of vascular wound healing [GO:0061044]; negative regulation of wound healing [GO:0061045]; positive regulation of bone mineralization [GO:0030501]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; regulation of cellular response to oxidative stress [GO:1900407]; regulation of cytokine production involved in inflammatory response [GO:1900015]; regulation of fat cell differentiation [GO:0045598]; regulation of inflammatory response [GO:0050727]; regulation of inflammatory response to wounding [GO:0106014]; regulation of insulin secretion [GO:0050796]; regulation of reactive oxygen species biosynthetic process [GO:1903426] GO:0001937; GO:0002232; GO:0002523; GO:0002540; GO:0004051; GO:0004052; GO:0005506; GO:0005576; GO:0005615; GO:0005635; GO:0005641; GO:0005654; GO:0005829; GO:0006691; GO:0006959; GO:0016363; GO:0016525; GO:0016702; GO:0016787; GO:0019369; GO:0019370; GO:0019372; GO:0030501; GO:0031965; GO:0034440; GO:0034774; GO:0036336; GO:0036403; GO:0042593; GO:0042759; GO:0043651; GO:0045598; GO:0048471; GO:0050727; GO:0050728; GO:0050796; GO:0051122; GO:0061044; GO:0061045; GO:0106014; GO:1900015; GO:1900407; GO:1901753; GO:1903426; GO:1903573; GO:1903671; GO:1904813; GO:1904999; GO:2001301 67 XM_029351145.2 0 30 14 81 46 NA NA NA NA NA NA 68 XM_029337805.2 1304 865 1461 1121 1215 O09131 1.41e-51 Glutathione S-transferase omega-1 (GSTO-1) (EC 2.5.1.18) (Glutathione S-transferase omega 1-1) (GSTO 1-1) (Glutathione-dependent dehydroascorbate reductase) (EC 1.8.5.1) (Monomethylarsonic acid reductase) (MMA(V) reductase) (EC 1.20.4.2) (S-(Phenacyl)glutathione reductase) (SPG-R) (p28) Mus musculus (Mouse) cellular response to arsenic-containing substance [GO:0071243]; glutathione metabolic process [GO:0006749]; L-ascorbic acid biosynthetic process [GO:0019853]; L-ascorbic acid metabolic process [GO:0019852]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; xenobiotic catabolic process [GO:0042178] GO:0004364; GO:0005604; GO:0005737; GO:0005829; GO:0006749; GO:0010880; GO:0016491; GO:0019852; GO:0019853; GO:0030424; GO:0031965; GO:0042178; GO:0043209; GO:0044297; GO:0045174; GO:0050610; GO:0060315; GO:0060316; GO:0071243 69 XM_044307687.1 0 125 36 72 116 NA NA NA NA NA NA 70 XM_029329527.2 4448 3044 2537 3532 2840 Q3UQ28 8.56e-86 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 71 XM_044321358.1 64 10 109 0 22 NA NA NA NA NA NA 72 XM_029341410.2 34 76 32 38 130 Q32LB9 1.52e-75 Nitric oxide-associated protein 1 Bos taurus (Bovine) apoptotic process [GO:0006915]; mitochondrial translation [GO:0032543]; regulation of cell death [GO:0010941]; regulation of cellular respiration [GO:0043457] GO:0005525; GO:0005743; GO:0006915; GO:0010941; GO:0032543; GO:0043457 73 XM_029325183.2 18 138 54 247 127 Q9EP82 5.57e-44 tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 (Protein Wuho homolog) (mWH) (WD repeat-containing protein 4) Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; RNA (guanine-N7)-methylation [GO:0036265]; tRNA methylation [GO:0030488]; tRNA modification [GO:0006400] GO:0005634; GO:0005654; GO:0005694; GO:0005829; GO:0006400; GO:0006974; GO:0030488; GO:0036265; GO:0043527 74 XM_044307023.1 0 0 2 0 8 P0DP43 5.67e-34 Cation channel sperm-associated auxiliary subunit epsilon (CatSper-epsilon) (CatSperepsilon) (C1orf101-like protein) Mus musculus (Mouse) flagellated sperm motility [GO:0030317]; sperm capacitation [GO:0048240] GO:0030317; GO:0036128; GO:0048240; GO:0097228 75 XM_029333541.2 3713 5804 2790 3085 2604 NA NA NA NA NA NA 76 XM_044313596.1 134 121 0 155 276 A9C3R9 8.04e-117 All-trans-retinyl ester 13-cis isomerohydrolase (13cIMH) (EC 3.1.1.90) (Lutein isomerase) (Meso-zeaxanthin isomerase) (EC 5.3.3.22) (Retinal pigment epithelium-specific 65 kDa protein homolog B) (RPE56b) Danio rerio (Zebrafish) (Brachydanio rerio) retinoid metabolic process [GO:0001523]; zeaxanthin biosynthetic process [GO:1901827] GO:0001523; GO:0005789; GO:0005886; GO:0016702; GO:0016787; GO:0046872; GO:0050251; GO:1901827 77 XM_029331475.2 197 368 60 20 125 NA NA NA NA NA NA 78 XM_029343026.2 523 378 361 273 1009 Q2TA37 8.07e-81 ADP-ribosylation factor-like protein 2 Bos taurus (Bovine) adherens junction assembly [GO:0034333]; bicellular tight junction assembly [GO:0070830]; centrosome cycle [GO:0007098]; maintenance of protein location in nucleus [GO:0051457]; negative regulation of GTPase activity [GO:0034260]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of microtubule polymerization [GO:0031116]; protein folding [GO:0006457]; regulation of aerobic respiration [GO:1903715]; regulation of glycolytic process [GO:0006110] GO:0003924; GO:0005525; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005739; GO:0005758; GO:0005794; GO:0005813; GO:0005829; GO:0005925; GO:0006110; GO:0006457; GO:0007098; GO:0010811; GO:0015630; GO:0016328; GO:0019003; GO:0031116; GO:0034260; GO:0034333; GO:0051457; GO:0070830; GO:1903715 79 XM_029330373.2 18 1 15 0 105 NA NA NA NA NA NA 80 XM_029331089.2 127 81 0 118 346 Q9BXB4 0 Oxysterol-binding protein-related protein 11 (ORP-11) (OSBP-related protein 11) Homo sapiens (Human) fat cell differentiation [GO:0045444]; positive regulation of sequestering of triglyceride [GO:0010890] GO:0005654; GO:0005794; GO:0005829; GO:0010890; GO:0015248; GO:0016020; GO:0031902; GO:0032934; GO:0043231; GO:0045444 81 XM_044306794.1 169 33 40 72 57 A0JMW2 0 Dynein axonemal assembly factor 5 (HEAT repeat-containing protein 2) Xenopus laevis (African clawed frog) cell projection organization [GO:0030030] GO:0030030; GO:0120293 82 XM_029340298.2 0 114 12 0 0 Q15434 2.21e-80 RNA-binding motif, single-stranded-interacting protein 2 (Suppressor of CDC2 with RNA-binding motif 3) Homo sapiens (Human) RNA processing [GO:0006396] GO:0003723; GO:0003730; GO:0005634; GO:0005829; GO:0006396; GO:0008143; GO:0008266; GO:1990904 83 XM_044318273.1 451 601 139 250 251 NA NA NA NA NA NA 84 XM_044324763.1 2 5 0 11 0 Q96RW7 2.47e-63 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 85 XM_044324763.1 2 5 0 11 0 Q96RW7 3.35e-54 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 86 XM_044324763.1 2 5 0 11 0 Q96RW7 5.72e-54 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 87 XM_044324763.1 2 5 0 11 0 Q96RW7 1.4e-52 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 88 XM_044324763.1 2 5 0 11 0 Q96RW7 5.78e-52 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 89 XM_044324763.1 2 5 0 11 0 Q96RW7 3.01e-49 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 90 XM_044324763.1 2 5 0 11 0 Q96RW7 1.69e-47 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 91 XM_044324763.1 2 5 0 11 0 Q96RW7 2.8e-44 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 92 XM_044324763.1 2 5 0 11 0 Q96RW7 3.33e-41 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 93 XM_044324763.1 2 5 0 11 0 Q96RW7 1.09e-39 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 94 XM_044324763.1 2 5 0 11 0 Q96RW7 2.64e-35 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 95 XM_029336641.2 218 556 153 699 1306 O88576 0 Sodium-dependent neutral amino acid transporter B(0)AT3 (Sodium- and chloride-dependent transporter XTRP2) (Solute carrier family 6 member 18) (System B(0) neutral amino acid transporter AT3) Mus musculus (Mouse) amino acid transmembrane transport [GO:0003333]; neurotransmitter transport [GO:0006836]; neutral amino acid transport [GO:0015804]; renal amino acid absorption [GO:1990297]; sodium ion transmembrane transport [GO:0035725] GO:0003333; GO:0005886; GO:0006836; GO:0015175; GO:0015804; GO:0016324; GO:0031526; GO:0035725; GO:0140931; GO:1990297 96 XM_044319320.1 1008 702 639 767 794 Q17GZ9 5.98e-145 Actin-related protein 5 Aedes aegypti (Yellowfever mosquito) (Culex aegypti) chromatin remodeling [GO:0006338]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006281; GO:0006310; GO:0006338; GO:0006355 97 XM_029338314.2 3504 2450 1691 2330 1833 Q2TBA3 9.56e-71 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog (EC 3.4.22.-) (Paracaspase) Mus musculus (Mouse) activation of NF-kappaB-inducing kinase activity [GO:0007250]; B cell activation [GO:0042113]; B-1 B cell differentiation [GO:0001923]; cellular response to lipopolysaccharide [GO:0071222]; innate immune response [GO:0045087]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; nuclear export [GO:0051168]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T-helper 17 cell differentiation [GO:2000321]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of apoptotic process [GO:0042981]; regulation of T cell receptor signaling pathway [GO:0050856]; response to fungus [GO:0009620]; T cell proliferation [GO:0042098]; T cell receptor signaling pathway [GO:0050852] GO:0001650; GO:0001923; GO:0002020; GO:0002096; GO:0002726; GO:0004175; GO:0004197; GO:0004842; GO:0005634; GO:0005737; GO:0005829; GO:0006508; GO:0007250; GO:0008233; GO:0009620; GO:0019209; GO:0031663; GO:0032449; GO:0032731; GO:0032743; GO:0032991; GO:0036094; GO:0042098; GO:0042113; GO:0042802; GO:0042981; GO:0043280; GO:0043621; GO:0045087; GO:0048471; GO:0050852; GO:0050856; GO:0050870; GO:0051092; GO:0051168; GO:0051603; GO:0071222; GO:2000321 98 XM_029345720.2 0 0 16 9 15 NA NA NA NA NA NA 99 XM_029352416.2 32 0 0 0 0 A6H603 5.12e-92 NACHT domain- and WD repeat-containing protein 1 Mus musculus (Mouse) negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of gene expression [GO:0010628] GO:0005524; GO:0005730; GO:0005829; GO:0010628; GO:0032088 100 XM_044325060.1 10 0 1 0 10 NA NA NA NA NA NA 101 XR_006397098.1 9 0 0 0 28 NA NA NA NA NA NA 102 XM_029340639.2 537 226 235 360 408 Q498G2 2.92e-70 Centrosomal protein of 152 kDa (Cep152) Xenopus laevis (African clawed frog) cell projection organization [GO:0030030]; centriole replication [GO:0007099]; de novo centriole assembly involved in multi-ciliated epithelial cell differentiation [GO:0098535] GO:0000242; GO:0005737; GO:0005814; GO:0007099; GO:0030030; GO:0098535; GO:0098536 103 XM_044318491.1 41 1052 76 23 40 NA NA NA NA NA NA 104 XM_029353050.2 1131 1111 460 652 696 NA NA NA NA NA NA 105 XM_044308809.1 209 32 395 277 565 NA NA NA NA NA NA 106 XM_044320264.1 0 0 53 0 143 NA NA NA NA NA NA 107 XM_044311574.1 5 0 4 7 18 NA NA NA NA NA NA 108 XR_006395319.1 219 264 106 184 286 NA NA NA NA NA NA 109 XM_044320645.1 0 24 18 18 0 NA NA NA NA NA NA 110 XR_006393893.1 41 2 25 5 151 NA NA NA NA NA NA 111 XM_029335884.2 100 101 0 100 34 NA NA NA NA NA NA 112 XM_029350452.2 46 0 0 0 279 Q66I21 0 2-aminomuconic semialdehyde dehydrogenase (EC 1.2.1.32) (Aldehyde dehydrogenase family 8 member A1) Danio rerio (Zebrafish) (Brachydanio rerio) L-kynurenine catabolic process [GO:0097053]; liver development [GO:0001889]; retinoic acid metabolic process [GO:0042573] GO:0001758; GO:0001889; GO:0005737; GO:0016620; GO:0042573; GO:0047102; GO:0097053 113 XM_029332793.2 248 75 41 128 68 NA NA NA NA NA NA 114 XM_044309348.1 1681 1066 1200 1170 4315 NA NA NA NA NA NA 115 XM_044316872.1 92 0 0 0 0 Q9Y5X5 1.99e-33 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (G-protein coupled receptor HLWAR77) (Neuropeptide G-protein coupled receptor) Homo sapiens (Human) detection of abiotic stimulus [GO:0009582]; G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0009582; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 116 XM_044312521.1 150 31 0 0 0 Q02356 0 AMP deaminase 2 (EC 3.5.4.6) (AMP deaminase isoform L) Rattus norvegicus (Rat) AMP metabolic process [GO:0046033]; ATP metabolic process [GO:0046034]; cholesterol homeostasis [GO:0042632]; cyclic purine nucleotide metabolic process [GO:0052652]; energy homeostasis [GO:0097009]; GTP metabolic process [GO:0046039]; IMP biosynthetic process [GO:0006188]; IMP salvage [GO:0032264]; nucleotide metabolic process [GO:0009117]; podocyte development [GO:0072015] GO:0003876; GO:0005829; GO:0006188; GO:0009117; GO:0032264; GO:0042632; GO:0046033; GO:0046034; GO:0046039; GO:0046872; GO:0052652; GO:0072015; GO:0097009 117 XM_029329890.2 1362 1365 833 1466 1108 NA NA NA NA NA NA 118 XM_029335562.2 14 0 0 0 36 NA NA NA NA NA NA 119 XM_044316495.1 0 21 14 0 20 NA NA NA NA NA NA 120 XM_044321891.1 751 745 378 695 627 Q7T3F7 1.43e-82 Cysteine and histidine-rich domain-containing protein 1 (CHORD domain-containing protein 1) (Morgana) Danio rerio (Zebrafish) (Brachydanio rerio) centrosome duplication [GO:0051298]; regulation of centrosome duplication [GO:0010824] GO:0008270; GO:0010824; GO:0051298 121 XM_044328579.1 98 0 55 110 0 Q95LR0 2.49e-72 Cilia- and flagella-associated protein 91 (CFAP91) (AMY-1-associating protein expressed in testis 1) (AAT-1) (MYCBP/AMY-1-associated testis-expressed protein 1) (Protein MAATS1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) axonemal central apparatus assembly [GO:1904158]; cell differentiation [GO:0030154]; cilium movement [GO:0003341]; spermatogenesis [GO:0007283] GO:0003341; GO:0005739; GO:0005930; GO:0007283; GO:0030154; GO:0031514; GO:1904158 122 XM_044328579.1 98 0 55 110 0 Q95LR0 2.49e-72 Cilia- and flagella-associated protein 91 (CFAP91) (AMY-1-associating protein expressed in testis 1) (AAT-1) (MYCBP/AMY-1-associated testis-expressed protein 1) (Protein MAATS1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) axonemal central apparatus assembly [GO:1904158]; cell differentiation [GO:0030154]; cilium movement [GO:0003341]; spermatogenesis [GO:0007283] GO:0003341; GO:0005739; GO:0005930; GO:0007283; GO:0030154; GO:0031514; GO:1904158 123 XM_044316520.1 48 72 5 11 57 NA NA NA NA NA NA 124 XM_044321295.1 0 6 0 102 100 A6QLD2 9.65e-53 Olfactomedin-like protein 2B Bos taurus (Bovine) extracellular matrix organization [GO:0030198]; signal transduction [GO:0007165] GO:0005615; GO:0007165; GO:0030198; GO:0031012; GO:0042802; GO:0050840 125 XR_003827564.2 103 101 19 143 32 NA NA NA NA NA NA 126 XM_044323292.1 0 51 0 0 0 Q5R5U3 4.57e-83 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 127 XM_044323292.1 0 51 0 0 0 Q5R5U3 1.19e-82 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 128 XM_044323292.1 0 51 0 0 0 Q5R5U3 7.94e-79 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 129 XM_044323292.1 0 51 0 0 0 Q5R5U3 4.84e-78 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 130 XM_044323292.1 0 51 0 0 0 Q5R5U3 1.03e-71 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 131 XM_044323292.1 0 51 0 0 0 Q5R5U3 6.93e-62 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 132 XM_044323292.1 0 51 0 0 0 Q5R5U3 2.2e-60 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 133 XM_044320426.1 101 3 13 102 163 NA NA NA NA NA NA 134 XM_044321698.1 1048 748 550 1379 1259 Q63415 3.32e-112 Proprotein convertase subtilisin/kexin type 6 (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin-like proprotein convertase 4) (SPC4) (Subtilisin/kexin-like protease PACE4) Rattus norvegicus (Rat) determination of left/right symmetry [GO:0007368]; glycoprotein metabolic process [GO:0009100]; nerve growth factor production [GO:0032902]; peptide hormone processing [GO:0016486]; protein processing [GO:0016485]; secretion by cell [GO:0032940]; zygotic determination of anterior/posterior axis, embryo [GO:0007354] GO:0004175; GO:0004252; GO:0005615; GO:0007354; GO:0007368; GO:0008201; GO:0009100; GO:0009986; GO:0016020; GO:0016485; GO:0016486; GO:0032902; GO:0032940; GO:0048406; GO:0062023 135 XM_029343044.2 261 400 293 236 245 Q9ER41 3.66e-69 Torsin-1B (Torsin ATPase-1B) (EC 3.6.4.-) (Torsin family 1 member B) Mus musculus (Mouse) chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum organization [GO:0007029]; nuclear membrane organization [GO:0071763]; protein localization to nucleus [GO:0034504] GO:0005524; GO:0005635; GO:0005737; GO:0005783; GO:0005788; GO:0007029; GO:0016887; GO:0019894; GO:0031965; GO:0034504; GO:0042802; GO:0051085; GO:0071763 136 XM_029351436.2 34 7 6 48 59 B8VIU6 2.25e-44 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 137 XR_006395568.1 117 25 10 21 21 NA NA NA NA NA NA 138 XM_044309925.1 19 3 2 2 2 NA NA NA NA NA NA 139 XM_029346833.2 514 522 404 953 776 NA NA NA NA NA NA 140 XM_044320526.1 949 1664 687 1955 1314 NA NA NA NA NA NA 141 XM_029342620.2 5 0 11 0 5 P53603 0 Formimidoyltransferase-cyclodeaminase (Formiminotransferase-cyclodeaminase) (FTCD) [Includes: Glutamate formimidoyltransferase (EC 2.1.2.5) (Glutamate formiminotransferase) (Glutamate formyltransferase); Formimidoyltetrahydrofolate cyclodeaminase (EC 4.3.1.4) (Formiminotetrahydrofolate cyclodeaminase)] Sus scrofa (Pig) histidine catabolic process [GO:0006548]; histidine catabolic process to glutamate and formamide [GO:0019556]; histidine catabolic process to glutamate and formate [GO:0019557] GO:0005542; GO:0005794; GO:0005814; GO:0005829; GO:0006548; GO:0019556; GO:0019557; GO:0030409; GO:0030412 142 XR_006391974.1 283 23 198 529 202 NA NA NA NA NA NA 143 XR_003822847.2 0 0 0 0 109 NA NA NA NA NA NA 144 XM_029349965.2 4123 3174 2732 3378 3764 Q9H8Y8 2.17e-119 Golgi reassembly-stacking protein 2 (GRS2) (Golgi phosphoprotein 6) (GOLPH6) (Golgi reassembly-stacking protein of 55 kDa) (GRASP55) (p59) Homo sapiens (Human) cell differentiation [GO:0030154]; establishment of protein localization to plasma membrane [GO:0061951]; Golgi organization [GO:0007030]; organelle assembly [GO:0070925]; organelle organization [GO:0006996]; response to endoplasmic reticulum stress [GO:0034976]; spermatogenesis [GO:0007283] GO:0000139; GO:0005789; GO:0005794; GO:0005801; GO:0006996; GO:0007030; GO:0007283; GO:0016020; GO:0030154; GO:0034976; GO:0061951; GO:0070925 145 XR_006391296.1 2 0 13 2 51 NA NA NA NA NA NA 146 XM_044319598.1 239 149 295 717 320 NA NA NA NA NA NA 147 XR_003826440.2 19 33 42 24 66 NA NA NA NA NA NA 148 XM_029345836.2 1867 1098 966 1848 1583 Q8AV28 4.52e-80 Pericentriolar material 1 protein (PCM-1) Gallus gallus (Chicken) centrosome cycle [GO:0007098]; cilium assembly [GO:0060271]; intraciliary transport involved in cilium assembly [GO:0035735]; microtubule anchoring at centrosome [GO:0034454]; positive regulation of intracellular protein transport [GO:0090316]; protein localization to centrosome [GO:0071539] GO:0005737; GO:0005813; GO:0005814; GO:0007098; GO:0034451; GO:0034454; GO:0035735; GO:0036064; GO:0060271; GO:0071539; GO:0090316 149 XR_006393669.1 102 7 48 109 73 Q5U2T8 9.78e-64 Corepressor interacting with RBPJ 1 (CBF1-interacting corepressor) Rattus norvegicus (Rat) in utero embryonic development [GO:0001701]; mRNA processing [GO:0006397]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; RNA splicing [GO:0008380] GO:0000122; GO:0001701; GO:0003714; GO:0005634; GO:0005737; GO:0005813; GO:0006397; GO:0008380; GO:0016607; GO:0019901; GO:0032991; GO:0042826; GO:0044877; GO:0045892 150 XM_029352917.2 314 312 180 446 225 Q8NEG5 4.3e-96 E3 ubiquitin-protein ligase ZSWIM2 (EC 2.3.2.27) (MEKK1-related protein X) (MEX) (RING-type E3 ubiquitin transferase ZSWIM2) (ZZ-type zinc finger-containing protein 2) (Zinc finger SWIM domain-containing protein 2) Homo sapiens (Human) apoptotic process [GO:0006915]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; protein polyubiquitination [GO:0000209] GO:0000209; GO:0006915; GO:0008270; GO:0043621; GO:0061630; GO:1902043 151 XM_044319621.1 4 17 22 12 4 NA NA NA NA NA NA 152 XM_044315616.1 1188 1034 993 1641 1681 F1MKX4 0 Proteasome activator complex subunit 4 (Proteasome activator PA200) Bos taurus (Bovine) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; sperm DNA condensation [GO:0035092] GO:0005634; GO:0005829; GO:0006281; GO:0006974; GO:0010499; GO:0016504; GO:0016607; GO:0035092; GO:0070577; GO:0070628; GO:1990111 153 XM_029350551.2 1025 1047 353 971 699 Q9BST9 4.83e-52 Rhotekin Homo sapiens (Human) actomyosin contractile ring assembly [GO:0000915]; apoptotic process [GO:0006915]; mitotic cytokinesis [GO:0000281]; regulation of apoptotic process [GO:0042981]; Rho protein signal transduction [GO:0007266]; septin ring organization [GO:0031106]; signal transduction [GO:0007165] GO:0000281; GO:0000915; GO:0005095; GO:0005525; GO:0005826; GO:0005829; GO:0006915; GO:0007165; GO:0007266; GO:0031106; GO:0031267; GO:0042981 154 XM_044320801.1 49 33 90 92 77 NA NA NA NA NA NA 155 XM_029324913.2 1032 858 601 852 642 A0A0B4J1F4 2.87e-40 Arrestin domain-containing protein 4 Mus musculus (Mouse) extracellular vesicle biogenesis [GO:0140112]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein transport [GO:0015031]; protein ubiquitination [GO:0016567] GO:0005737; GO:0005768; GO:0005769; GO:0005886; GO:0015031; GO:0016567; GO:0043231; GO:0051443; GO:0140112; GO:1903561; GO:1990756 156 XM_029328568.2 3 0 0 43 77 NA NA NA NA NA NA 157 XR_006395542.1 189 1 121 621 37 Q7RTR2 2.75e-49 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 158 XR_006395542.1 189 1 121 621 37 Q7RTR2 1.82e-46 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 159 XR_006395542.1 189 1 121 621 37 Q7RTR2 1.11e-43 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 160 XM_029334068.2 920 673 209 614 328 Q9NTG7 7.01e-121 NAD-dependent protein deacetylase sirtuin-3, mitochondrial (hSIRT3) (EC 2.3.1.286) (Regulatory protein SIR2 homolog 3) (SIR2-like protein 3) Homo sapiens (Human) aerobic respiration [GO:0009060]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of catalase activity [GO:1902553]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of superoxide dismutase activity [GO:1901671]; protein deacetylation [GO:0006476] GO:0005634; GO:0005654; GO:0005739; GO:0005759; GO:0006476; GO:0008270; GO:0009060; GO:0016740; GO:0017136; GO:0032991; GO:0034979; GO:0034983; GO:0043565; GO:0070403; GO:1901671; GO:1902553; GO:2000304 161 XM_044322586.1 1258 979 902 2358 2736 Q8TE73 0 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5) Homo sapiens (Human) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0005524; GO:0005576; GO:0005737; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 162 XM_044322586.1 1258 979 902 2358 2736 Q8TE73 4.6e-143 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5) Homo sapiens (Human) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0005524; GO:0005576; GO:0005737; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 163 XM_044322586.1 1258 979 902 2358 2736 Q8TE73 7.4e-123 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5) Homo sapiens (Human) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0005524; GO:0005576; GO:0005737; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 164 XM_044322586.1 1258 979 902 2358 2736 Q8TE73 1.04e-26 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5) Homo sapiens (Human) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0005524; GO:0005576; GO:0005737; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 165 XM_029353111.2 14 3 28 12 61 A0A8B8EY61 6.63e-88 NA NA NA NA 166 XM_044325218.1 40 0 0 0 0 P47972 1.75e-23 Neuronal pentraxin-2 (NP2) (Neuronal pentraxin II) (NP-II) Homo sapiens (Human) associative learning [GO:0008306]; chemical synaptic transmission [GO:0007268]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962] GO:0005576; GO:0007268; GO:0008306; GO:0030246; GO:0046872; GO:0098962; GO:0098978 167 XM_029343588.2 413 335 187 223 328 O96019 0 Actin-like protein 6A (53 kDa BRG1-associated factor A) (Actin-related protein Baf53a) (ArpNbeta) (BRG1-associated factor 53A) (BAF53A) (INO80 complex subunit K) Homo sapiens (Human) blastocyst formation [GO:0001825]; chromatin remodeling [GO:0006338]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; histone acetylation [GO:0016573]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; negative regulation of cell differentiation [GO:0045596]; nervous system development [GO:0007399]; neural retina development [GO:0003407]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of telomere maintenance in response to DNA damage [GO:1904507]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of chromosome organization [GO:0033044]; regulation of DNA repair [GO:0006282]; regulation of DNA replication [GO:0006275]; regulation of DNA strand elongation [GO:0060382]; regulation of DNA-templated transcription [GO:0006355]; regulation of double-strand break repair [GO:2000779]; regulation of embryonic development [GO:0045995]; regulation of G0 to G1 transition [GO:0070316]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of nucleotide-excision repair [GO:2000819]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; spinal cord development [GO:0021510]; telomere maintenance [GO:0000723] GO:0000723; GO:0000776; GO:0000785; GO:0000786; GO:0001825; GO:0003407; GO:0003682; GO:0003713; GO:0005634; GO:0005654; GO:0005886; GO:0006275; GO:0006281; GO:0006282; GO:0006310; GO:0006338; GO:0006355; GO:0006357; GO:0007165; GO:0007399; GO:0008284; GO:0016363; GO:0016514; GO:0016573; GO:0016586; GO:0021510; GO:0030071; GO:0031011; GO:0032991; GO:0033044; GO:0035060; GO:0035267; GO:0042981; GO:0043967; GO:0043968; GO:0045582; GO:0045596; GO:0045597; GO:0045663; GO:0045739; GO:0045893; GO:0045995; GO:0051726; GO:0060382; GO:0070316; GO:0071564; GO:0140288; GO:1902459; GO:1904507; GO:1905168; GO:2000045; GO:2000779; GO:2000781; GO:2000819 168 XM_044318918.1 36 0 20 3 5 NA NA NA NA NA NA 169 XR_006396398.1 5 3 5 54 37 P08537 1.05e-42 Tubulin alpha chain (EC 3.6.5.-) [Cleaved into: Detyrosinated tubulin alpha chain] Xenopus laevis (African clawed frog) microtubule-based process [GO:0007017] GO:0005200; GO:0005525; GO:0005737; GO:0005874; GO:0007017; GO:0016787; GO:0046872 170 XR_006394769.1 0 0 10 0 8 NA NA NA NA NA NA 171 XM_044309953.1 0 0 0 15 3 Q7SIC1 9.55e-28 Fucolectin Anguilla anguilla (European freshwater eel) (Muraena anguilla) regulation of cellular defense response [GO:0010185]; regulation of complement activation, lectin pathway [GO:0001868]; regulation of innate immune response [GO:0045088] GO:0001868; GO:0005509; GO:0005576; GO:0010185; GO:0030246; GO:0042806; GO:0045088 172 XM_029349576.2 48 64 46 88 92 Q921Y4 1.52e-29 Molybdate-anion transporter (Major facilitator superfamily domain-containing protein 5) (Molybdate transporter 2 homolog) Mus musculus (Mouse) NA GO:0005886; GO:0015098 173 XM_044317766.1 1640 985 759 1841 1315 P23468 1.39e-129 Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48) Homo sapiens (Human) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; neuron differentiation [GO:0030182]; phosphate-containing compound metabolic process [GO:0006796]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse assembly [GO:0051965]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; regulation of immune response [GO:0050776]; regulation of postsynaptic density assembly [GO:0099151]; synaptic membrane adhesion [GO:0099560]; trans-synaptic signaling by trans-synaptic complex [GO:0099545]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185] GO:0004725; GO:0005001; GO:0005102; GO:0005886; GO:0006470; GO:0006796; GO:0007157; GO:0007185; GO:0030182; GO:0042734; GO:0046426; GO:0050775; GO:0050776; GO:0050804; GO:0050839; GO:0051965; GO:0070062; GO:0097105; GO:0098685; GO:0098686; GO:0098978; GO:0099054; GO:0099151; GO:0099545; GO:0099560 174 XM_044317766.1 1640 985 759 1841 1315 P23468 9.33e-53 Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48) Homo sapiens (Human) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; neuron differentiation [GO:0030182]; phosphate-containing compound metabolic process [GO:0006796]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse assembly [GO:0051965]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; regulation of immune response [GO:0050776]; regulation of postsynaptic density assembly [GO:0099151]; synaptic membrane adhesion [GO:0099560]; trans-synaptic signaling by trans-synaptic complex [GO:0099545]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185] GO:0004725; GO:0005001; GO:0005102; GO:0005886; GO:0006470; GO:0006796; GO:0007157; GO:0007185; GO:0030182; GO:0042734; GO:0046426; GO:0050775; GO:0050776; GO:0050804; GO:0050839; GO:0051965; GO:0070062; GO:0097105; GO:0098685; GO:0098686; GO:0098978; GO:0099054; GO:0099151; GO:0099545; GO:0099560 175 XM_044312416.1 95 17 56 22 68 NA NA NA NA NA NA 176 XM_029336049.2 731 571 447 553 621 NA NA NA NA NA NA 177 XM_044307806.1 0 3 0 11 0 P0DP43 1.4e-37 Cation channel sperm-associated auxiliary subunit epsilon (CatSper-epsilon) (CatSperepsilon) (C1orf101-like protein) Mus musculus (Mouse) flagellated sperm motility [GO:0030317]; sperm capacitation [GO:0048240] GO:0030317; GO:0036128; GO:0048240; GO:0097228 178 XM_044323807.1 17 31 96 75 14 NA NA NA NA NA NA 179 XR_006394164.1 274 4 155 20 28 NA NA NA NA NA NA 180 XR_006396523.1 54 32 31 69 83 NA NA NA NA NA NA 181 XM_029349355.2 474 449 282 600 373 Q8NBN7 1.41e-74 Retinol dehydrogenase 13 (EC 1.1.1.300) (Short chain dehydrogenase/reductase family 7C member 3) Homo sapiens (Human) eye photoreceptor cell development [GO:0042462]; response to high light intensity [GO:0009644]; retina layer formation [GO:0010842]; retinal metabolic process [GO:0042574] GO:0005743; GO:0009644; GO:0010842; GO:0042462; GO:0042574; GO:0052650 182 XM_044322510.1 91 83 38 158 115 NA NA NA NA NA NA 183 XM_029356281.2 86 0 0 0 0 NA NA NA NA NA NA 184 XM_029355858.2 23 29 7 44 96 NA NA NA NA NA NA 185 XM_044313287.1 17 20 20 45 27 NA NA NA NA NA NA 186 XM_029327940.2 247 58 269 63 47 Q96T23 2.21e-36 Remodeling and spacing factor 1 (Rsf-1) (HBV pX-associated protein 8) (Hepatitis B virus X-associated protein) (p325 subunit of RSF chromatin-remodeling complex) Homo sapiens (Human) chromatin remodeling [GO:0006338]; DNA-templated transcription initiation [GO:0006352]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-templated transcription [GO:0045892]; nucleosome assembly [GO:0006334]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of viral transcription [GO:0050434]; regulation of DNA-templated transcription [GO:0006355] GO:0003712; GO:0005634; GO:0005654; GO:0006334; GO:0006338; GO:0006352; GO:0006355; GO:0031213; GO:0042393; GO:0043392; GO:0045892; GO:0045893; GO:0045944; GO:0046872; GO:0050434; GO:0140751 187 XM_029327940.2 247 58 269 63 47 Q96T23 6.1e-27 Remodeling and spacing factor 1 (Rsf-1) (HBV pX-associated protein 8) (Hepatitis B virus X-associated protein) (p325 subunit of RSF chromatin-remodeling complex) Homo sapiens (Human) chromatin remodeling [GO:0006338]; DNA-templated transcription initiation [GO:0006352]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-templated transcription [GO:0045892]; nucleosome assembly [GO:0006334]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of viral transcription [GO:0050434]; regulation of DNA-templated transcription [GO:0006355] GO:0003712; GO:0005634; GO:0005654; GO:0006334; GO:0006338; GO:0006352; GO:0006355; GO:0031213; GO:0042393; GO:0043392; GO:0045892; GO:0045893; GO:0045944; GO:0046872; GO:0050434; GO:0140751 188 XM_029337133.2 219 126 52 93 154 Q8TAQ5 2.39e-141 Zinc finger protein 420 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005654; GO:0006357; GO:0046872 189 XM_029337133.2 219 126 52 93 154 Q8TAQ5 1.68e-136 Zinc finger protein 420 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005654; GO:0006357; GO:0046872 190 XM_029337133.2 219 126 52 93 154 Q8TAQ5 1.63e-130 Zinc finger protein 420 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005654; GO:0006357; GO:0046872 191 XM_029337133.2 219 126 52 93 154 Q8TAQ5 3.57e-126 Zinc finger protein 420 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005654; GO:0006357; GO:0046872 192 XM_029337133.2 219 126 52 93 154 Q8TAQ5 4.3e-115 Zinc finger protein 420 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005654; GO:0006357; GO:0046872 193 XM_029337133.2 219 126 52 93 154 Q8TAQ5 5.67e-66 Zinc finger protein 420 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005654; GO:0006357; GO:0046872 194 XM_029349048.2 4 9 16 35 17 NA NA NA NA NA NA 195 XM_044317080.1 16 0 4 9 236 Q8BGK5 8.73e-100 Solute carrier family 35 member F1 Mus musculus (Mouse) NA GO:0016020; GO:0022857 196 XM_029343950.2 12 0 0 2 14 P34456 9.49e-26 Uncharacterized protein F54H12.2 Caenorhabditis elegans deoxyribonucleotide biosynthetic process [GO:0009263] GO:0004748; GO:0005829; GO:0009263 197 XM_029323586.2 2 3 0 0 10 NA NA NA NA NA NA 198 XM_029341602.2 519 447 218 642 433 P22288 2.87e-99 GTP cyclohydrolase 1 (EC 3.5.4.16) (GTP cyclohydrolase I) (GTP-CH-I) Rattus norvegicus (Rat) 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; dihydrobiopterin metabolic process [GO:0051066]; dopamine biosynthetic process [GO:0042416]; negative regulation of blood pressure [GO:0045776]; neuromuscular process controlling posture [GO:0050884]; positive regulation of heart rate [GO:0010460]; positive regulation of nitric-oxide synthase activity [GO:0051000]; protein-containing complex assembly [GO:0065003]; pteridine-containing compound biosynthetic process [GO:0042559]; regulation of blood pressure [GO:0008217]; regulation of lung blood pressure [GO:0014916]; regulation of removal of superoxide radicals [GO:2000121]; response to lipopolysaccharide [GO:0032496]; response to pain [GO:0048265]; response to tumor necrosis factor [GO:0034612]; response to type II interferon [GO:0034341]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; vasodilation [GO:0042311] GO:0003924; GO:0003934; GO:0005509; GO:0005525; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006729; GO:0008217; GO:0008270; GO:0010460; GO:0014916; GO:0030742; GO:0031369; GO:0031410; GO:0031965; GO:0032496; GO:0032991; GO:0034341; GO:0034612; GO:0035998; GO:0042311; GO:0042416; GO:0042559; GO:0042802; GO:0042803; GO:0044877; GO:0045776; GO:0046654; GO:0048265; GO:0050884; GO:0051000; GO:0051019; GO:0051066; GO:0065003; GO:2000121 199 XM_029349077.2 0 0 21 0 0 Q58D31 7.81e-135 Sorbitol dehydrogenase (SDH) (EC 1.1.1.-) (L-iditol 2-dehydrogenase) (EC 1.1.1.14) (Polyol dehydrogenase) (Xylitol dehydrogenase) (XDH) (EC 1.1.1.9) Bos taurus (Bovine) flagellated sperm motility [GO:0030317]; sorbitol catabolic process [GO:0006062] GO:0003939; GO:0006062; GO:0008270; GO:0030317; GO:0031514; GO:0031966; GO:0046526 200 XM_044307389.1 247 194 267 540 504 Q8VCK5 2.37e-49 Kelch-like protein 20 (Kelch-like ECT2-interacting protein) Mus musculus (Mouse) Golgi to endosome transport [GO:0006895]; negative regulation of apoptotic process [GO:0043066]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K33-linked ubiquitination [GO:1990390]; protein transport [GO:0015031]; protein ubiquitination [GO:0016567] GO:0003779; GO:0004842; GO:0005737; GO:0005794; GO:0005802; GO:0005829; GO:0006895; GO:0015031; GO:0016567; GO:0016605; GO:0019964; GO:0030424; GO:0030425; GO:0031463; GO:0043066; GO:0043161; GO:0048471; GO:1990390 201 XM_029338743.2 0 61 46 38 22 Q8QHA5 0 DNA replication ATP-dependent helicase/nuclease DNA2 (DNA replication ATP-dependent helicase-like homolog) [Includes: DNA replication nuclease DNA2 (EC 3.1.-.-); DNA replication ATP-dependent helicase DNA2 (EC 3.6.4.12)] Xenopus laevis (African clawed frog) base-excision repair [GO:0006284]; DNA double-strand break processing [GO:0000729]; DNA replication [GO:0006260]; DNA replication checkpoint signaling [GO:0000076]; DNA replication, Okazaki fragment processing [GO:0033567]; DNA replication, removal of RNA primer [GO:0043137]; double-strand break repair via single-strand annealing [GO:0045002]; mitochondrial DNA replication [GO:0006264]; positive regulation of DNA replication [GO:0045740] GO:0000076; GO:0000729; GO:0003677; GO:0003678; GO:0004518; GO:0005524; GO:0005634; GO:0005739; GO:0006260; GO:0006264; GO:0006284; GO:0016887; GO:0016890; GO:0017108; GO:0017116; GO:0033567; GO:0043137; GO:0043139; GO:0045002; GO:0045740; GO:0046872; GO:0051539 202 XM_044315559.1 0 54 0 0 0 NA NA NA NA NA NA 203 XM_029335879.2 879 811 414 561 613 O15973 1.64e-30 Rhodopsin, GQ-coupled (GQ-rhodopsin) Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis) phototransduction [GO:0007602]; visual perception [GO:0007601] GO:0004930; GO:0005886; GO:0007601; GO:0007602; GO:0009881 204 XM_044325692.1 204 151 12 100 24 P15314 3.71e-27 Interferon regulatory factor 1 (IRF-1) Mus musculus (Mouse) apoptotic process [GO:0006915]; CD8-positive, alpha-beta T cell differentiation [GO:0043374]; cellular response to interferon-beta [GO:0035458]; cellular response to interleukin-1 [GO:0071347]; cellular response to mechanical stimulus [GO:0071260]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to tumor necrosis factor [GO:0071356]; defense response to virus [GO:0051607]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; immune system process [GO:0002376]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; positive regulation of cell death [GO:0010942]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of natural killer cell differentiation [GO:0032825]; positive regulation of T-helper 1 cell differentiation [GO:0045627]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of adaptive immune response [GO:0002819]; regulation of CD8-positive, alpha-beta T cell proliferation [GO:2000564]; regulation of cell cycle [GO:0051726]; regulation of gene expression [GO:0010468]; regulation of innate immune response [GO:0045088]; regulation of MyD88-dependent toll-like receptor signaling pathway [GO:0034124]; regulation of transcription by RNA polymerase II [GO:0006357]; response to growth hormone [GO:0060416]; transcription by RNA polymerase II [GO:0006366]; type II interferon-mediated signaling pathway [GO:0060333] GO:0000785; GO:0000976; GO:0000977; GO:0000978; GO:0000981; GO:0001228; GO:0002376; GO:0002819; GO:0003677; GO:0003700; GO:0005634; GO:0005737; GO:0006357; GO:0006366; GO:0006915; GO:0007249; GO:0010468; GO:0010942; GO:0032481; GO:0032728; GO:0032735; GO:0032825; GO:0034124; GO:0035458; GO:0042532; GO:0043374; GO:0043565; GO:0045088; GO:0045590; GO:0045627; GO:0045629; GO:0045892; GO:0045893; GO:0045944; GO:0051607; GO:0051726; GO:0060333; GO:0060416; GO:0071260; GO:0071347; GO:0071356; GO:0071375; GO:2000564 205 XM_044307273.1 101 35 96 57 79 NA NA NA NA NA NA 206 XM_029333564.2 577 439 202 493 402 P70627 9.95e-167 Glutamate carboxypeptidase 2 (EC 3.4.17.21) (Folate hydrolase 1) (Folylpoly-gamma-glutamate carboxypeptidase) (FGCP) (Glutamate carboxypeptidase II) (GCPII) (Membrane glutamate carboxypeptidase) (mGCP) (N-acetylated-alpha-linked acidic dipeptidase I) (NAALADase I) (Prostate-specific membrane antigen homolog) (Pteroylpoly-gamma-glutamate carboxypeptidase) Rattus norvegicus (Rat) C-terminal protein deglutamylation [GO:0035609]; folic acid-containing compound metabolic process [GO:0006760]; positive regulation of apoptotic process [GO:0043065]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508] GO:0004180; GO:0004181; GO:0005886; GO:0006508; GO:0006760; GO:0008233; GO:0009986; GO:0016020; GO:0016805; GO:0030163; GO:0035609; GO:0043065; GO:0046872; GO:1904492; GO:1904493 207 XM_029325697.2 1720 2062 835 1280 1233 O45782 1.52e-31 Arrestin domain-containing protein 17 (Calcineurin-interacting protein 1) Caenorhabditis elegans behavior [GO:0007610]; protein transport [GO:0015031] GO:0005737; GO:0007610; GO:0015031; GO:0030346 208 XM_044317033.1 63 7 2 10 31 Q6P2X9 2.78e-41 Monocarboxylate transporter 12 (MCT 12) (Solute carrier family 16 member 12) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) creatine transmembrane transport [GO:0015881]; creatinine metabolic process [GO:0046449] GO:0005308; GO:0005886; GO:0015292; GO:0015881; GO:0016323; GO:0046449 209 XM_044319732.1 42 25 7 51 9 NA NA NA NA NA NA 210 XM_044320715.1 51 10 42 15 8 NA NA NA NA NA NA 211 XM_044321453.1 311 562 0 0 409 O43900 1.29e-130 Prickle planar cell polarity protein 3 (LIM domain only protein 6) (LMO-6) (Prickle-like protein 3) (Pk3) (Triple LIM domain protein 6) Homo sapiens (Human) cell projection organization [GO:0030030] GO:0005739; GO:0005886; GO:0008270; GO:0030030 212 XM_029332356.2 0 0 0 0 8 Q5XJN2 5.07e-49 Gamma-interferon-inducible lysosomal thiol reductase (EC 1.8.-.-) (Gamma-interferon-inducible protein IP-30) Danio rerio (Zebrafish) (Brachydanio rerio) immune system process [GO:0002376] GO:0002376; GO:0005576; GO:0005764; GO:0016491; GO:0016667; GO:0016671; GO:0047134 213 XM_029328232.2 70 92 32 116 56 NA NA NA NA NA NA 214 XM_044310916.1 232 6 68 61 58 NA NA NA NA NA NA 215 XM_029337681.2 119 81 50 77 131 Q6NXH2 8.22e-156 Glycoprotein endo-alpha-1,2-mannosidase (Endo-alpha mannosidase) (Endomannosidase) (mEndo) (EC 3.2.1.130) Mus musculus (Mouse) NA GO:0000139; GO:0004559; GO:0004569; GO:0005794 216 XM_044312912.1 170 206 58 116 301 NA NA NA NA NA NA 217 XR_006394335.1 436 62 225 267 41 NA NA NA NA NA NA 218 XM_044319071.1 786 914 459 1260 1602 Q921G7 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial (ETF-QO) (ETF-ubiquinone oxidoreductase) (EC 1.5.5.1) (Electron-transferring-flavoprotein dehydrogenase) (ETF dehydrogenase) Mus musculus (Mouse) electron transport chain [GO:0022900]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; response to oxidative stress [GO:0006979] GO:0004174; GO:0005739; GO:0005743; GO:0006979; GO:0009055; GO:0016020; GO:0016491; GO:0017133; GO:0022900; GO:0031966; GO:0033539; GO:0046872; GO:0048038; GO:0048039; GO:0051536; GO:0051539 219 XM_029329116.2 1351 1456 950 2075 1268 Q5IS35 1.13e-95 Mitochondrial thiamine pyrophosphate carrier (Solute carrier family 25 member 19) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) thiamine pyrophosphate transmembrane transport [GO:0030974] GO:0005739; GO:0015297; GO:0030974; GO:0031966; GO:0090422 220 XR_003824147.2 732 1588 1069 1426 1141 NA NA NA NA NA NA 221 XM_044324719.1 129 40 121 224 107 Q1L8I0 1.03e-105 Pseudouridylate synthase PUS7L (EC 5.4.99.-) (Pseudouridylate synthase 7 homolog-like protein) Danio rerio (Zebrafish) (Brachydanio rerio) mRNA processing [GO:0006397]; mRNA pseudouridine synthesis [GO:1990481]; pseudouridine synthesis [GO:0001522] GO:0001522; GO:0003723; GO:0005634; GO:0006397; GO:0009982; GO:1990481 222 XM_029344235.2 14353 17673 9525 11387 4699 Q9CPW5 6.95e-56 Translocon-associated protein subunit beta (TRAP-beta) (Signal sequence receptor subunit beta) (SSR-beta) Mus musculus (Mouse) in utero embryonic development [GO:0001701] GO:0001701; GO:0005789 223 XM_029353960.2 92 48 92 74 82 Q6AYJ2 8.67e-24 Biorientation of chromosomes in cell division protein 1 (Biorientation defective protein 1) (Protein FAM44B) Rattus norvegicus (Rat) cell division [GO:0051301]; mitotic metaphase plate congression [GO:0007080]; mitotic sister chromatid biorientation [GO:1990758]; mitotic sister chromatid cohesion, centromeric [GO:0071962]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; protein localization to chromosome, centromeric region [GO:0071459] GO:0000922; GO:0000940; GO:0004864; GO:0005737; GO:0005813; GO:0005876; GO:0007080; GO:0032515; GO:0048188; GO:0051301; GO:0051721; GO:0071459; GO:0071962; GO:1990758 224 XM_029331427.2 651 584 583 762 1128 Q70VZ7 3.16e-127 2-acylglycerol O-acyltransferase 1 (EC 2.3.1.22) (Acyl CoA:monoacylglycerol acyltransferase 1) (MGAT1) (Monoacylglycerol O-acyltransferase 1) Bos taurus (Bovine) diacylglycerol biosynthetic process [GO:0006651]; glycerol metabolic process [GO:0006071]; lipid metabolic process [GO:0006629]; triglyceride biosynthetic process [GO:0019432] GO:0003846; GO:0004144; GO:0005789; GO:0006071; GO:0006629; GO:0006651; GO:0008374; GO:0019432 225 XR_006392405.1 4 7 17 3 39 NA NA NA NA NA NA 226 XM_029329606.2 130 161 119 180 244 Q8NEA4 7e-47 F-box only protein 36 Homo sapiens (Human) NA NA 227 XM_044307748.1 103 19 39 114 76 NA NA NA NA NA NA 228 XR_006396227.1 121 0 53 0 223 NA NA NA NA NA NA 229 XM_044312285.1 0 31 5 18 0 P15620 8.72e-55 Zinc finger protein 271 (Zinc finger protein 35) (Zfp-35) Mus musculus (Mouse) cell differentiation [GO:0030154]; inflammatory response to antigenic stimulus [GO:0002437]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; negative regulation of type 2 immune response [GO:0002829]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283] GO:0000978; GO:0001228; GO:0002437; GO:0002829; GO:0005634; GO:0006357; GO:0007283; GO:0030154; GO:0045629; GO:0046872 230 XM_044312285.1 0 31 5 18 0 P15620 4.12e-53 Zinc finger protein 271 (Zinc finger protein 35) (Zfp-35) Mus musculus (Mouse) cell differentiation [GO:0030154]; inflammatory response to antigenic stimulus [GO:0002437]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; negative regulation of type 2 immune response [GO:0002829]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283] GO:0000978; GO:0001228; GO:0002437; GO:0002829; GO:0005634; GO:0006357; GO:0007283; GO:0030154; GO:0045629; GO:0046872 231 XM_044312285.1 0 31 5 18 0 P15620 3.05e-52 Zinc finger protein 271 (Zinc finger protein 35) (Zfp-35) Mus musculus (Mouse) cell differentiation [GO:0030154]; inflammatory response to antigenic stimulus [GO:0002437]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; negative regulation of type 2 immune response [GO:0002829]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283] GO:0000978; GO:0001228; GO:0002437; GO:0002829; GO:0005634; GO:0006357; GO:0007283; GO:0030154; GO:0045629; GO:0046872 232 XM_044312285.1 0 31 5 18 0 P15620 1.04e-50 Zinc finger protein 271 (Zinc finger protein 35) (Zfp-35) Mus musculus (Mouse) cell differentiation [GO:0030154]; inflammatory response to antigenic stimulus [GO:0002437]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; negative regulation of type 2 immune response [GO:0002829]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283] GO:0000978; GO:0001228; GO:0002437; GO:0002829; GO:0005634; GO:0006357; GO:0007283; GO:0030154; GO:0045629; GO:0046872 233 XM_044312285.1 0 31 5 18 0 P15620 1.36e-49 Zinc finger protein 271 (Zinc finger protein 35) (Zfp-35) Mus musculus (Mouse) cell differentiation [GO:0030154]; inflammatory response to antigenic stimulus [GO:0002437]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; negative regulation of type 2 immune response [GO:0002829]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283] GO:0000978; GO:0001228; GO:0002437; GO:0002829; GO:0005634; GO:0006357; GO:0007283; GO:0030154; GO:0045629; GO:0046872 234 XM_044312285.1 0 31 5 18 0 P15620 2.69e-49 Zinc finger protein 271 (Zinc finger protein 35) (Zfp-35) Mus musculus (Mouse) cell differentiation [GO:0030154]; inflammatory response to antigenic stimulus [GO:0002437]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; negative regulation of type 2 immune response [GO:0002829]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283] GO:0000978; GO:0001228; GO:0002437; GO:0002829; GO:0005634; GO:0006357; GO:0007283; GO:0030154; GO:0045629; GO:0046872 235 XM_044312285.1 0 31 5 18 0 P15620 7.61e-49 Zinc finger protein 271 (Zinc finger protein 35) (Zfp-35) Mus musculus (Mouse) cell differentiation [GO:0030154]; inflammatory response to antigenic stimulus [GO:0002437]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; negative regulation of type 2 immune response [GO:0002829]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283] GO:0000978; GO:0001228; GO:0002437; GO:0002829; GO:0005634; GO:0006357; GO:0007283; GO:0030154; GO:0045629; GO:0046872 236 XM_044312285.1 0 31 5 18 0 P15620 2.07e-48 Zinc finger protein 271 (Zinc finger protein 35) (Zfp-35) Mus musculus (Mouse) cell differentiation [GO:0030154]; inflammatory response to antigenic stimulus [GO:0002437]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; negative regulation of type 2 immune response [GO:0002829]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283] GO:0000978; GO:0001228; GO:0002437; GO:0002829; GO:0005634; GO:0006357; GO:0007283; GO:0030154; GO:0045629; GO:0046872 237 XM_044312285.1 0 31 5 18 0 P15620 8.78e-47 Zinc finger protein 271 (Zinc finger protein 35) (Zfp-35) Mus musculus (Mouse) cell differentiation [GO:0030154]; inflammatory response to antigenic stimulus [GO:0002437]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; negative regulation of type 2 immune response [GO:0002829]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283] GO:0000978; GO:0001228; GO:0002437; GO:0002829; GO:0005634; GO:0006357; GO:0007283; GO:0030154; GO:0045629; GO:0046872 238 XM_044312285.1 0 31 5 18 0 P15620 1.21e-45 Zinc finger protein 271 (Zinc finger protein 35) (Zfp-35) Mus musculus (Mouse) cell differentiation [GO:0030154]; inflammatory response to antigenic stimulus [GO:0002437]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; negative regulation of type 2 immune response [GO:0002829]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283] GO:0000978; GO:0001228; GO:0002437; GO:0002829; GO:0005634; GO:0006357; GO:0007283; GO:0030154; GO:0045629; GO:0046872 239 XM_044312285.1 0 31 5 18 0 P15620 3.59e-42 Zinc finger protein 271 (Zinc finger protein 35) (Zfp-35) Mus musculus (Mouse) cell differentiation [GO:0030154]; inflammatory response to antigenic stimulus [GO:0002437]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; negative regulation of type 2 immune response [GO:0002829]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283] GO:0000978; GO:0001228; GO:0002437; GO:0002829; GO:0005634; GO:0006357; GO:0007283; GO:0030154; GO:0045629; GO:0046872 240 XM_044308499.1 10 2 10 0 4 NA NA NA NA NA NA 241 XM_029343893.2 562 40 456 502 442 NA NA NA NA NA NA 242 XM_044328750.1 242 87 176 366 772 Q7TN88 1.25e-60 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 243 XM_044328750.1 242 87 176 366 772 Q7TN88 4.19e-48 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 244 XM_044317253.1 1650 1313 10 1608 8 NA NA NA NA NA NA 245 XM_029323469.2 7887 5530 4448 6822 7111 P63081 2.18e-68 V-type proton ATPase 16 kDa proteolipid subunit c (V-ATPase 16 kDa proteolipid subunit c) (Vacuolar proton pump 16 kDa proteolipid subunit c) Rattus norvegicus (Rat) negative regulation of autophagic cell death [GO:1904093]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of Wnt signaling pathway [GO:0030177] GO:0000220; GO:0005764; GO:0005794; GO:0008021; GO:0016020; GO:0030177; GO:0030665; GO:0030672; GO:0031625; GO:0033176; GO:0046961; GO:0070374; GO:1902495; GO:1904093; GO:1904949 246 XM_044328090.1 911 737 926 1014 1293 Q6NZF1 2.57e-29 Zinc finger CCCH domain-containing protein 11A Mus musculus (Mouse) poly(A)+ mRNA export from nucleus [GO:0016973] GO:0000346; GO:0003729; GO:0016973; GO:0046872 247 XM_044314696.1 0 0 0 2 11 Q94K49 5.79e-40 Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1 (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) epigenetic regulation of gene expression [GO:0040029] GO:0003682; GO:0004518; GO:0005634; GO:0035098; GO:0035102; GO:0040029; GO:0046872 248 XM_029337083.2 121 0 60 194 57 NA NA NA NA NA NA 249 XR_003825649.2 51 25 45 30 94 NA NA NA NA NA NA 250 XM_029338374.2 303 184 118 136 182 A6QR44 3.6e-60 Microprocessor complex subunit DGCR8 (DiGeorge syndrome critical region 8 homolog) Bos taurus (Bovine) primary miRNA processing [GO:0031053] GO:0003725; GO:0005730; GO:0020037; GO:0031053; GO:0042802; GO:0046872; GO:0070877; GO:0070878 251 XR_006394691.1 54 70 52 42 26 NA NA NA NA NA NA 252 XM_044309120.1 22 0 23 0 11 NA NA NA NA NA NA 253 XM_044307402.1 374 98 39 187 17 Q9GZV3 1.67e-59 High affinity choline transporter 1 (Hemicholinium-3-sensitive choline transporter) (CHT) (Solute carrier family 5 member 7) Homo sapiens (Human) acetylcholine biosynthetic process [GO:0008292]; choline transport [GO:0015871]; in utero embryonic development [GO:0001701]; neuromuscular synaptic transmission [GO:0007274]; neurotransmitter transport [GO:0006836]; synaptic transmission, cholinergic [GO:0007271]; transmembrane transport [GO:0055085] GO:0001701; GO:0005307; GO:0005886; GO:0006836; GO:0007271; GO:0007274; GO:0008292; GO:0015220; GO:0015871; GO:0016020; GO:0030424; GO:0030425; GO:0031594; GO:0033265; GO:0043204; GO:0045202; GO:0055085 254 XM_044307402.1 374 98 39 187 17 Q9GZV3 1.67e-59 High affinity choline transporter 1 (Hemicholinium-3-sensitive choline transporter) (CHT) (Solute carrier family 5 member 7) Homo sapiens (Human) acetylcholine biosynthetic process [GO:0008292]; choline transport [GO:0015871]; in utero embryonic development [GO:0001701]; neuromuscular synaptic transmission [GO:0007274]; neurotransmitter transport [GO:0006836]; synaptic transmission, cholinergic [GO:0007271]; transmembrane transport [GO:0055085] GO:0001701; GO:0005307; GO:0005886; GO:0006836; GO:0007271; GO:0007274; GO:0008292; GO:0015220; GO:0015871; GO:0016020; GO:0030424; GO:0030425; GO:0031594; GO:0033265; GO:0043204; GO:0045202; GO:0055085 255 XM_044320788.1 626 383 351 739 763 NA NA NA NA NA NA 256 XM_044317096.1 2103 1819 1454 1792 2231 Q5U252 0 Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.4.19.12) (Deubiquitinating enzyme 47) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) Xenopus laevis (African clawed frog) base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; monoubiquitinated protein deubiquitination [GO:0035520]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004843; GO:0005737; GO:0006284; GO:0006511; GO:0006974; GO:0035520 257 XM_044317096.1 2103 1819 1454 1792 2231 Q5U252 4.45e-80 Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.4.19.12) (Deubiquitinating enzyme 47) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) Xenopus laevis (African clawed frog) base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; monoubiquitinated protein deubiquitination [GO:0035520]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004843; GO:0005737; GO:0006284; GO:0006511; GO:0006974; GO:0035520 258 XM_029351347.2 547 288 386 885 755 Q9PUU6 1.66e-33 Frizzled-2 (Fz-2) (Xfz2) Xenopus laevis (African clawed frog) Wnt signaling pathway [GO:0016055] GO:0004930; GO:0005886; GO:0016055 259 XM_029351347.2 547 288 386 885 755 Q9PUU6 2.57e-22 Frizzled-2 (Fz-2) (Xfz2) Xenopus laevis (African clawed frog) Wnt signaling pathway [GO:0016055] GO:0004930; GO:0005886; GO:0016055 260 XR_006393293.1 5 0 0 7 5 NA NA NA NA NA NA 261 XM_044309857.1 401 403 386 220 253 Q9M2U3 3.73e-30 Protein ALP1-like (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) NA GO:0000118; GO:0004518; GO:0046872 262 XM_029351332.2 2095 1467 1345 1666 1695 Q91YJ2 4.52e-108 Sorting nexin-4 Mus musculus (Mouse) endocytic recycling [GO:0032456]; positive regulation of autophagosome assembly [GO:2000786]; positive regulation of histamine secretion by mast cell [GO:1903595]; protein transport [GO:0015031] GO:0005154; GO:0005158; GO:0005737; GO:0005769; GO:0005868; GO:0005886; GO:0015031; GO:0016020; GO:0031201; GO:0031901; GO:0032266; GO:0032456; GO:0032991; GO:0035091; GO:0098830; GO:1903595; GO:1990459; GO:1990460; GO:2000786 263 XM_029342030.2 139 92 0 236 90 Q9EQS9 6.86e-80 Immunoglobulin superfamily DCC subclass member 4 (Neighbor of punc e11) (Protein DDM36) Mus musculus (Mouse) cell-cell adhesion [GO:0098609] GO:0005886; GO:0098609 264 XM_044315842.1 54 89 67 51 25 Q7RTR2 1.1e-38 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 265 XM_044315842.1 54 89 67 51 25 Q7RTR2 2.17e-36 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 266 XM_044315842.1 54 89 67 51 25 Q7RTR2 1.33e-30 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 267 XM_044315842.1 54 89 67 51 25 Q7RTR2 1.43e-26 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 268 XM_044315842.1 54 89 67 51 25 Q7RTR2 2.46e-22 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 269 XM_029353128.2 86 205 51 87 80 Q90YI8 4.72e-26 T-cell acute lymphocytic leukemia protein 1 (TAL-1) (FrSCL) (Stem cell protein) Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; definitive hemopoiesis [GO:0060216]; endocardium formation [GO:0060214]; erythrocyte differentiation [GO:0030218]; hemangioblast cell differentiation [GO:0060217]; hematopoietic stem cell differentiation [GO:0060218]; myeloid cell differentiation [GO:0030099]; primitive hemopoiesis [GO:0060215]; vasculogenesis [GO:0001570] GO:0000981; GO:0001525; GO:0001570; GO:0003677; GO:0005634; GO:0030099; GO:0030218; GO:0046983; GO:0048844; GO:0060214; GO:0060215; GO:0060216; GO:0060217; GO:0060218 270 XR_003824733.2 29 0 52 1 167 NA NA NA NA NA NA 271 XR_006392458.1 119 77 83 186 31 NA NA NA NA NA NA 272 XM_044312335.1 24 0 9 0 18 NA NA NA NA NA NA 273 XM_029356109.2 717 372 359 391 583 O88491 0 Histone-lysine N-methyltransferase, H3 lysine-36 specific (EC 2.1.1.357) (H3-K36-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) Mus musculus (Mouse) chromatin organization [GO:0006325]; gastrulation with mouth forming second [GO:0001702]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA-templated transcription [GO:0006355]; regulation of peptidyl-serine phosphorylation [GO:0033135]; regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903025] GO:0000122; GO:0000785; GO:0000978; GO:0001702; GO:0003682; GO:0003712; GO:0003714; GO:0005634; GO:0006325; GO:0006355; GO:0008270; GO:0030331; GO:0033135; GO:0035097; GO:0042054; GO:0042799; GO:0042974; GO:0045893; GO:0046965; GO:0046966; GO:0046975; GO:0050681; GO:0140954; GO:1903025 274 XM_044320225.1 0 285 0 0 0 NA NA NA NA NA NA 275 XM_029338520.2 1574 903 734 1255 1389 Q6P861 0 Serine/threonine-protein phosphatase 4 catalytic subunit (PP4C) (Pp4) (EC 3.1.3.16) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005634; GO:0005737; GO:0005815; GO:0017018; GO:0046872 276 XM_044327933.1 0 0 0 6 29 R1CW23 1.78e-90 Dimethylsulfonioproprionate lyase 7 (DMSP lyase 7) (EC 4.4.1.3) (Dimethylpropiothetin dethiomethylase 7) Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi) NA GO:0047869 277 XM_044323304.1 116 4 0 15 8 NA NA NA NA NA NA 278 XM_044309289.1 20 0 0 3 0 NA NA NA NA NA NA 279 XM_044313537.1 44 77 200 312 212 Q0R4F1 4.21e-38 ATP-dependent DNA helicase PIF1 (EC 3.6.4.12) (DNA repair and recombination helicase PIF1) Xenopus laevis (African clawed frog) DNA recombination [GO:0006310]; DNA repair [GO:0006281]; mitochondrial genome maintenance [GO:0000002]; telomere maintenance [GO:0000723] GO:0000002; GO:0000723; GO:0003677; GO:0005524; GO:0005634; GO:0005739; GO:0006281; GO:0006310; GO:0016887; GO:0043139 280 XM_029352474.2 53 10 88 10 0 NA NA NA NA NA NA 281 XM_029330443.2 419 378 173 387 452 NA NA NA NA NA NA 282 XM_044325987.1 0 0 5 0 21 NA NA NA NA NA NA 283 XR_006391360.1 352 361 226 381 585 NA NA NA NA NA NA 284 XR_006391857.1 78 15 17 6 0 NA NA NA NA NA NA 285 XM_044325031.1 15 33 15 10 13 NA NA NA NA NA NA 286 XM_029343825.2 3775 348 1114 1236 4096 Q90XC2 1.21e-132 Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never in mitosis A-related kinase 8) (NimA-related protein kinase 8) Danio rerio (Zebrafish) (Brachydanio rerio) animal organ morphogenesis [GO:0009887]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; determination of heart left/right asymmetry [GO:0061371]; heart looping [GO:0001947]; pronephros development [GO:0048793]; pronephros formation [GO:0072116]; protein phosphorylation [GO:0006468]; renal tubule development [GO:0061326] GO:0001947; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005929; GO:0006468; GO:0007059; GO:0009887; GO:0046872; GO:0048793; GO:0051301; GO:0061326; GO:0061371; GO:0072116; GO:0106310 287 XM_044317122.1 11 66 1717 128 0 NA NA NA NA NA NA 288 XM_044315056.1 379 131 202 441 220 A2AAY5 1.17e-108 SH3 and PX domain-containing protein 2B (Factor for adipocyte differentiation 49) (Tyrosine kinase substrate with four SH3 domains) Mus musculus (Mouse) adipose tissue development [GO:0060612]; bone development [GO:0060348]; cranial skeletal system development [GO:1904888]; extracellular matrix disassembly [GO:0022617]; eye development [GO:0001654]; heart development [GO:0007507]; osteoblast fate commitment [GO:0002051]; podosome assembly [GO:0071800]; positive regulation of adipose tissue development [GO:1904179]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of gene expression [GO:0010628]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of stress fiber assembly [GO:0051496]; protein localization to membrane [GO:0072657]; regulation of brood size [GO:0060378]; skeletal system development [GO:0001501]; skeletal system morphogenesis [GO:0048705]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801] GO:0001501; GO:0001654; GO:0002051; GO:0002102; GO:0005737; GO:0006801; GO:0007507; GO:0010314; GO:0010628; GO:0016176; GO:0022617; GO:0032266; GO:0040018; GO:0042169; GO:0042554; GO:0042995; GO:0045600; GO:0048705; GO:0051496; GO:0060348; GO:0060378; GO:0060612; GO:0070161; GO:0070273; GO:0071800; GO:0072657; GO:0080025; GO:1904179; GO:1904888 289 XR_006396800.1 25 41 17 13 24 NA NA NA NA NA NA 290 XM_044316768.1 455 240 327 1268 354 NA NA NA NA NA NA 291 XM_029344209.2 26 0 0 53 13 NA NA NA NA NA NA 292 XR_003824994.2 340 210 205 186 135 NA NA NA NA NA NA 293 XM_029333962.2 89 0 91 33 115 NA NA NA NA NA NA 294 XM_029328404.2 55 34 61 73 232 NA NA NA NA NA NA 295 XM_029355529.2 410 233 135 371 348 Q66JY6 2.57e-35 Rho guanine nucleotide exchange factor 39 Mus musculus (Mouse) positive regulation of cell migration [GO:0030335] GO:0005085; GO:0005886; GO:0030335 296 XM_029327288.2 844 432 417 481 586 O42406 1.11e-113 Homeobox protein SIX3 (CSIX3) (Sine oculis homeobox homolog 3) Gallus gallus (Chicken) apoptotic process involved in development [GO:1902742]; brain development [GO:0007420]; cell proliferation in forebrain [GO:0021846]; epithelial cell maturation [GO:0002070]; eye development [GO:0001654]; forebrain dorsal/ventral pattern formation [GO:0021798]; lens development in camera-type eye [GO:0002088]; lens fiber cell apoptotic process [GO:1990086]; lens fiber cell differentiation [GO:0070306]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of Wnt signaling pathway [GO:0030178]; neuroblast differentiation [GO:0014016]; neuroblast migration [GO:0097402]; optic vesicle morphogenesis [GO:0003404]; pituitary gland development [GO:0021983]; proximal/distal axis specification [GO:0009946]; regulation of cell cycle phase transition [GO:1901987]; regulation of cell population proliferation [GO:0042127]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neural retina development [GO:0061074]; regulation of neuroblast proliferation [GO:1902692]; regulation of transcription by RNA polymerase II [GO:0006357]; telencephalon development [GO:0021537]; telencephalon regionalization [GO:0021978] GO:0000978; GO:0000981; GO:0001228; GO:0001654; GO:0002070; GO:0002088; GO:0003404; GO:0003677; GO:0005634; GO:0005667; GO:0006357; GO:0007420; GO:0009946; GO:0014016; GO:0021537; GO:0021798; GO:0021846; GO:0021978; GO:0021983; GO:0030178; GO:0042127; GO:0045665; GO:0045892; GO:0061074; GO:0070306; GO:0097402; GO:1901987; GO:1902692; GO:1902742; GO:1990086; GO:2000177 297 XM_044321796.1 3503 4505 2214 4337 3574 P10809 0 60 kDa heat shock protein, mitochondrial (EC 5.6.1.7) (60 kDa chaperonin) (Chaperonin 60) (CPN60) (Heat shock protein 60) (HSP-60) (Hsp60) (HuCHA60) (Mitochondrial matrix protein P1) (P60 lymphocyte protein) Homo sapiens (Human) 'de novo' protein folding [GO:0006458]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic mitochondrial changes [GO:0008637]; B cell activation [GO:0042113]; B cell proliferation [GO:0042100]; biological process involved in interaction with symbiont [GO:0051702]; cellular response to interleukin-7 [GO:0098761]; chaperone-mediated protein complex assembly [GO:0051131]; isotype switching to IgG isotypes [GO:0048291]; mitochondrial unfolded protein response [GO:0034514]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; negative regulation of apoptotic process [GO:0043066]; positive regulation of apoptotic process [GO:0043065]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of macrophage activation [GO:0043032]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell mediated immune response to tumor cell [GO:0002842]; positive regulation of type II interferon production [GO:0032729]; protein folding [GO:0006457]; protein import into mitochondrial intermembrane space [GO:0045041]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; response to cold [GO:0009409]; response to unfolded protein [GO:0006986]; T cell activation [GO:0042110] GO:0001530; GO:0002039; GO:0002755; GO:0002842; GO:0003688; GO:0003697; GO:0003723; GO:0003725; GO:0005524; GO:0005615; GO:0005737; GO:0005739; GO:0005743; GO:0005759; GO:0005769; GO:0005829; GO:0005886; GO:0005905; GO:0006457; GO:0006458; GO:0006919; GO:0006986; GO:0008035; GO:0008637; GO:0009409; GO:0009986; GO:0016020; GO:0016853; GO:0016887; GO:0019899; GO:0030135; GO:0030141; GO:0031625; GO:0032727; GO:0032729; GO:0032733; GO:0032735; GO:0032755; GO:0032991; GO:0034185; GO:0034186; GO:0034514; GO:0042026; GO:0042100; GO:0042110; GO:0042113; GO:0043032; GO:0043065; GO:0043066; GO:0045041; GO:0046696; GO:0048291; GO:0050821; GO:0050870; GO:0051082; GO:0051087; GO:0051131; GO:0051604; GO:0051702; GO:0070062; GO:0097225; GO:0097524; GO:0098761; GO:0140494; GO:0140662 298 XM_044328920.1 34 399 62 54 30 Q2LE78 1.08e-74 BTB/POZ domain-containing protein 6 Xenopus laevis (African clawed frog) NA GO:0005737 299 XM_029328064.2 2 0 2 128 14 NA NA NA NA NA NA 300 XM_044323986.1 136 152 0 0 0 NA NA NA NA NA NA 301 XM_044323708.1 0 2 2 0 14 O02751 8.98e-28 Craniofacial development protein 2 (p97 bucentaur protein) Bos taurus (Bovine) chromatin remodeling [GO:0006338] GO:0003824; GO:0005634; GO:0005737; GO:0006338 302 XM_044321845.1 551 504 117 482 625 Q5ZJ65 1.79e-46 Protein FAM76A Gallus gallus (Chicken) NA GO:0005654; GO:0016607 303 XM_029340173.2 441 455 286 670 271 NA NA NA NA NA NA 304 XM_044318168.1 0 25 75 0 0 O75762 4.31e-100 Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation-sensitive protein p120) (p120) (Wasabi receptor) Homo sapiens (Human) calcium ion transmembrane transport [GO:0070588]; cell surface receptor signaling pathway [GO:0007166]; cellular calcium ion homeostasis [GO:0006874]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to organic substance [GO:0071310]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; ion transport [GO:0006811]; protein homotetramerization [GO:0051289]; response to cold [GO:0009409]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; sensory perception of pain [GO:0019233]; thermoception [GO:0050955] GO:0005262; GO:0005886; GO:0006811; GO:0006874; GO:0007166; GO:0009409; GO:0009410; GO:0010033; GO:0014070; GO:0015267; GO:0015278; GO:0019233; GO:0032421; GO:0042802; GO:0048265; GO:0050955; GO:0050966; GO:0050968; GO:0051289; GO:0070301; GO:0070588; GO:0071310; GO:0097604 305 XM_044309113.1 706 216 507 304 371 NA NA NA NA NA NA 306 XM_044320297.1 0 0 0 0 16 NA NA NA NA NA NA 307 XM_029344251.2 38 0 0 0 0 Q9NPF2 1.35e-38 Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4S-1) (C4ST-1) (C4ST1) Homo sapiens (Human) apoptotic process [GO:0006915]; carbohydrate biosynthetic process [GO:0016051]; chondrocyte development [GO:0002063]; chondroitin sulfate biosynthetic process [GO:0030206]; developmental growth [GO:0048589]; embryonic digit morphogenesis [GO:0042733]; embryonic viscerocranium morphogenesis [GO:0048703]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; polysaccharide localization [GO:0033037]; post-anal tail morphogenesis [GO:0036342]; post-embryonic development [GO:0009791]; proteoglycan biosynthetic process [GO:0030166]; regulation of cell population proliferation [GO:0042127]; respiratory gaseous exchange by respiratory system [GO:0007585]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0000139; GO:0001537; GO:0001701; GO:0002063; GO:0006915; GO:0007179; GO:0007585; GO:0008146; GO:0009791; GO:0016020; GO:0016051; GO:0030166; GO:0030206; GO:0030512; GO:0033037; GO:0036342; GO:0042127; GO:0042733; GO:0043066; GO:0047756; GO:0048589; GO:0048703; GO:0050659 308 XM_029343676.2 1827 1170 952 1724 1367 P10090 0 Protein white (EC 7.6.2.-) (EC 7.6.2.6) (ATP-binding cassette transporter sub-family G member white) (Broad substrate specificity ATP-binding cassette transporter white) Drosophila melanogaster (Fruit fly) aminergic neurotransmitter loading into synaptic vesicle [GO:0015842]; biogenic amine biosynthetic process [GO:0042401]; cGMP transport [GO:0070731]; compound eye pigmentation [GO:0048072]; eye pigment metabolic process [GO:0042441]; eye pigment precursor transport [GO:0006856]; gravitaxis [GO:0042332]; guanine transport [GO:0015854]; histamine uptake [GO:0051615]; male courtship behavior [GO:0008049]; memory [GO:0007613]; ommochrome biosynthetic process [GO:0006727]; riboflavin transport [GO:0032218]; transmembrane transport [GO:0055085]; tryptophan transport [GO:0015827]; xanthine transport [GO:0042906] GO:0005275; GO:0005524; GO:0005886; GO:0006727; GO:0006856; GO:0007613; GO:0008049; GO:0008558; GO:0015196; GO:0015208; GO:0015827; GO:0015842; GO:0015854; GO:0016020; GO:0016887; GO:0022857; GO:0030659; GO:0031409; GO:0031410; GO:0032217; GO:0032218; GO:0042332; GO:0042401; GO:0042441; GO:0042626; GO:0042906; GO:0042907; GO:0048072; GO:0048770; GO:0051615; GO:0055085; GO:0070731; GO:0090741; GO:0098793; GO:1905948 309 XM_029338316.2 944 2366 578 1095 831 Q2TBA3 7.04e-72 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog (EC 3.4.22.-) (Paracaspase) Mus musculus (Mouse) activation of NF-kappaB-inducing kinase activity [GO:0007250]; B cell activation [GO:0042113]; B-1 B cell differentiation [GO:0001923]; cellular response to lipopolysaccharide [GO:0071222]; innate immune response [GO:0045087]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; nuclear export [GO:0051168]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T-helper 17 cell differentiation [GO:2000321]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of apoptotic process [GO:0042981]; regulation of T cell receptor signaling pathway [GO:0050856]; response to fungus [GO:0009620]; T cell proliferation [GO:0042098]; T cell receptor signaling pathway [GO:0050852] GO:0001650; GO:0001923; GO:0002020; GO:0002096; GO:0002726; GO:0004175; GO:0004197; GO:0004842; GO:0005634; GO:0005737; GO:0005829; GO:0006508; GO:0007250; GO:0008233; GO:0009620; GO:0019209; GO:0031663; GO:0032449; GO:0032731; GO:0032743; GO:0032991; GO:0036094; GO:0042098; GO:0042113; GO:0042802; GO:0042981; GO:0043280; GO:0043621; GO:0045087; GO:0048471; GO:0050852; GO:0050856; GO:0050870; GO:0051092; GO:0051168; GO:0051603; GO:0071222; GO:2000321 310 XR_006394706.1 125 40 13 142 37 NA NA NA NA NA NA 311 XM_029338132.2 0 0 293 91 0 Q5RBN8 6.56e-102 Protein lin-54 homolog Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cell cycle [GO:0007049] GO:0003677; GO:0005634; GO:0007049; GO:0046872 312 XM_044313548.1 98 33 98 58 71 NA NA NA NA NA NA 313 XM_029333030.2 0 8 7 6 3 NA NA NA NA NA NA 314 XR_003826362.2 303 206 265 220 235 O54991 1.34e-26 Contactin-associated protein 1 (Caspr) (Caspr1) (MHDNIV) (NCP1) (Neurexin IV) (Neurexin-4) (Paranodin) Mus musculus (Mouse) axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cytoskeleton organization [GO:0007010]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process [GO:0050905]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuronal action potential propagation [GO:0019227]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; postsynaptic density organization [GO:0097106]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; regulation of synapse maturation [GO:0090128] GO:0002175; GO:0005886; GO:0005918; GO:0007005; GO:0007010; GO:0007155; GO:0007409; GO:0016020; GO:0017124; GO:0019227; GO:0022010; GO:0022011; GO:0030424; GO:0030913; GO:0031175; GO:0033010; GO:0033270; GO:0042552; GO:0043209; GO:0048786; GO:0048812; GO:0050884; GO:0050885; GO:0050905; GO:0071205; GO:0090128; GO:0097106; GO:0098529; GO:0098978; GO:1990227 315 XM_044316981.1 854 563 683 774 1079 NA NA NA NA NA NA 316 XM_044318239.1 38 5 0 192 333 Q9HAR2 2.38e-68 Adhesion G protein-coupled receptor L3 (Calcium-independent alpha-latrotoxin receptor 3) (CIRL-3) (Latrophilin-3) (Lectomedin-3) Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; brain development [GO:0007420]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; G protein-coupled receptor signaling pathway [GO:0007186]; neuron migration [GO:0001764]; synapse assembly [GO:0007416] GO:0001764; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007166; GO:0007186; GO:0007189; GO:0007416; GO:0007420; GO:0016020; GO:0030246; GO:0030424; GO:0098742; GO:0098978 317 XM_029338043.2 0 12 0 50 37 NA NA NA NA NA NA 318 XM_044327834.1 38 45 6 24 16 NA NA NA NA NA NA 319 XR_006393156.1 559 925 409 670 387 NA NA NA NA NA NA 320 XM_029343961.2 528 382 281 447 345 Q556Y8 8.59e-32 Probable rhodanese domain-containing dual specificity protein phosphatase (EC 3.1.3.16) (EC 3.1.3.48) Dictyostelium discoideum (Social amoeba) negative regulation of MAPK cascade [GO:0043409]; protein dephosphorylation [GO:0006470]; response to cisplatin [GO:0072718]; sorocarp development [GO:0030587] GO:0004721; GO:0004725; GO:0005737; GO:0006470; GO:0008330; GO:0017017; GO:0017018; GO:0030587; GO:0043409; GO:0072718 321 XM_029358075.2 292 733 399 268 619 Q5C9L6 1.26e-68 (S)-coclaurine N-methyltransferase (TfCNMT) (EC 2.1.1.140) Thalictrum flavum subsp. glaucum (Yellow meadow rue) methylation [GO:0032259] GO:0005737; GO:0030794; GO:0032259 322 XM_044307897.1 62 30 32 13 46 NA NA NA NA NA NA 323 XM_029333644.2 1093 783 806 947 968 Q9JJT0 1.42e-166 RNA 3'-terminal phosphate cyclase-like protein Mus musculus (Mouse) endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000480]; endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000447]; endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000479]; rRNA processing [GO:0006364] GO:0000447; GO:0000479; GO:0000480; GO:0004521; GO:0005730; GO:0006364 324 XM_029328624.2 235 94 131 137 147 Q3UMM4 1.99e-166 Cyclin-dependent kinase 10 (EC 2.7.11.22) (Cell division protein kinase 10) Mus musculus (Mouse) cell projection organization [GO:0030030]; negative regulation of cilium assembly [GO:1902018]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of MAPK cascade [GO:0043410]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of mitotic cell cycle [GO:0007346] GO:0000307; GO:0004674; GO:0004693; GO:0005524; GO:0005634; GO:0005737; GO:0006468; GO:0007346; GO:0018107; GO:0030030; GO:0032956; GO:0036064; GO:0043410; GO:0097472; GO:0106310; GO:1902018; GO:1902749 325 XM_044312182.1 6 0 5 16 37 NA NA NA NA NA NA 326 XM_029323614.2 2620 1560 1448 2702 1435 Q6DHC1 1.75e-108 Ras-related protein Rab-18-B Danio rerio (Zebrafish) (Brachydanio rerio) brain development [GO:0007420]; chordate embryonic development [GO:0043009]; eye development [GO:0001654]; intracellular protein transport [GO:0006886]; lipid droplet organization [GO:0034389] GO:0001654; GO:0003924; GO:0005525; GO:0005794; GO:0005811; GO:0006886; GO:0007420; GO:0012505; GO:0016324; GO:0034389; GO:0043009 327 XM_029342859.2 29 3 14 0 48 NA NA NA NA NA NA 328 XM_029332184.2 89 201 136 89 144 Q503Q1 7.12e-44 Mitochondria-eating protein (Spermatogenesis-associated protein 18) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to DNA damage stimulus [GO:0006974]; mitochondrial protein catabolic process [GO:0035694]; mitophagy by induced vacuole formation [GO:0035695]; response to steroid hormone [GO:0048545] GO:0005737; GO:0005741; GO:0006974; GO:0035694; GO:0035695; GO:0043231; GO:0048545 329 XM_029336027.2 1908 1389 1110 2031 1489 Q9NSI6 0 Bromodomain and WD repeat-containing protein 1 (WD repeat-containing protein 9) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; regulation of cell shape [GO:0008360]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0005634; GO:0005654; GO:0005730; GO:0005829; GO:0006357; GO:0007010; GO:0008360 330 XM_029336027.2 1908 1389 1110 2031 1489 Q9NSI6 2.75e-124 Bromodomain and WD repeat-containing protein 1 (WD repeat-containing protein 9) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; regulation of cell shape [GO:0008360]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0005634; GO:0005654; GO:0005730; GO:0005829; GO:0006357; GO:0007010; GO:0008360 331 XM_044319932.1 7 0 0 1 3 NA NA NA NA NA NA 332 XR_003828511.2 22 14 10 40 40 NA NA NA NA NA NA 333 XM_044328435.1 3914 4077 2321 4833 5231 P48509 6.68e-37 CD151 antigen (GP27) (Membrane glycoprotein SFA-1) (Platelet-endothelial tetraspan antigen 3) (PETA-3) (Tetraspanin-24) (Tspan-24) (CD antigen CD151) Homo sapiens (Human) cell adhesion [GO:0007155]; cell migration [GO:0016477]; positive regulation of cell migration [GO:0030335]; positive regulation of endocytosis [GO:0045807]; T cell proliferation [GO:0042098]; wound healing, spreading of cells [GO:0044319] GO:0005178; GO:0005604; GO:0005829; GO:0005886; GO:0005925; GO:0007155; GO:0009986; GO:0016020; GO:0016477; GO:0030335; GO:0042098; GO:0044319; GO:0045807 334 XM_044310308.1 0 3 0 31 3 Q9NR20 6.85e-80 Dual specificity tyrosine-phosphorylation-regulated kinase 4 (EC 2.7.12.1) Homo sapiens (Human) peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107] GO:0004674; GO:0004712; GO:0004713; GO:0005524; GO:0005634; GO:0005737; GO:0005856; GO:0018105; GO:0018107; GO:0043231; GO:0046872; GO:0106310 335 XR_006393480.1 1 64 11 48 68 NA NA NA NA NA NA 336 XM_029352420.2 318 119 123 356 512 NA NA NA NA NA NA 337 XM_044319605.1 50 55 58 33 95 P32320 1.87e-39 Cytidine deaminase (EC 3.5.4.5) (Cytidine aminohydrolase) Homo sapiens (Human) cell surface receptor signaling pathway [GO:0007166]; cellular response to external biotic stimulus [GO:0071217]; cytidine deamination [GO:0009972]; cytosine metabolic process [GO:0019858]; negative regulation of cell growth [GO:0030308]; negative regulation of nucleotide metabolic process [GO:0045980]; pyrimidine-containing compound salvage [GO:0008655]; response to cycloheximide [GO:0046898]; UMP salvage [GO:0044206] GO:0001882; GO:0004126; GO:0005576; GO:0005829; GO:0007166; GO:0008270; GO:0008655; GO:0009972; GO:0019858; GO:0030308; GO:0034774; GO:0042802; GO:0042803; GO:0044206; GO:0045980; GO:0046898; GO:0047844; GO:0071217; GO:1904724; GO:1904813 338 XM_029339042.2 965 516 676 791 2186 NA NA NA NA NA NA 339 XM_029327033.2 101 9 70 29 0 Q8VDL9 5.27e-67 Zinc finger protein GLIS2 (GLI-similar 2) (Neuronal Krueppel-like protein) (Zinc finger protein GLI5) Mus musculus (Mouse) cell differentiation involved in kidney development [GO:0061005]; central nervous system development [GO:0007417]; hematopoietic stem cell homeostasis [GO:0061484]; kidney development [GO:0001822]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000976; GO:0000977; GO:0000978; GO:0000981; GO:0001228; GO:0001822; GO:0003677; GO:0003700; GO:0005634; GO:0005654; GO:0005667; GO:0005737; GO:0006357; GO:0007417; GO:0016607; GO:0043433; GO:0045879; GO:0045892; GO:0045893; GO:0045944; GO:0046872; GO:0061005; GO:0061484; GO:0097730; GO:1900182; GO:1990837 340 XM_044314107.1 68 37 34 7 87 NA NA NA NA NA NA 341 XR_006393781.1 2 1 12 2 23 NA NA NA NA NA NA 342 XM_044327919.1 11 0 0 15 0 NA NA NA NA NA NA 343 XR_006394368.1 14 0 4 0 17 NA NA NA NA NA NA 344 XM_029346166.2 154 110 83 140 47 O05510 3.69e-36 Putative fructokinase (EC 2.7.1.4) (Glucomannan utilization protein E) Bacillus subtilis (strain 168) negative regulation of DNA-templated transcription [GO:0045892]; polysaccharide catabolic process [GO:0000272] GO:0000272; GO:0005524; GO:0008865; GO:0045892; GO:0046872 345 XM_044327453.1 0 6 0 5 23 O43854 3.55e-22 EGF-like repeat and discoidin I-like domain-containing protein 3 (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1) Homo sapiens (Human) cell adhesion [GO:0007155]; positive regulation of cell-substrate adhesion [GO:0010811] GO:0005178; GO:0005509; GO:0007155; GO:0010811; GO:0062023; GO:0070062; GO:1903561 346 XM_029328052.2 274 128 213 307 330 G8HTB6 7.53e-44 ZP domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 347 XM_029343333.2 13421 14409 10170 10122 8427 Q5RF07 2.79e-21 Small integral membrane protein 14 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0005783; GO:0005789 348 XM_044320799.1 34 38 23 75 76 NA NA NA NA NA NA 349 XM_044309143.1 2360 1671 1151 2269 2151 O35867 1.87e-50 Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (PP1bp175) (Protein phosphatase 1 regulatory subunit 9A) (p180) Rattus norvegicus (Rat) actin filament organization [GO:0007015]; aging [GO:0007568]; calcium-mediated signaling [GO:0019722]; cellular response to toxic substance [GO:0097237]; excitatory postsynaptic potential [GO:0060079]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of spontaneous neurotransmitter secretion [GO:1904049]; negative regulation of stress fiber assembly [GO:0051497]; neuron development [GO:0048666]; neuron projection development [GO:0031175]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of long-term synaptic depression [GO:1900454]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein kinase activity [GO:0045860]; postsynaptic actin cytoskeleton organization [GO:0098974]; regulation of actin filament polymerization [GO:0030833]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of filopodium assembly [GO:0051489]; regulation of synapse assembly [GO:0051963]; regulation of synapse structural plasticity [GO:0051823] GO:0005737; GO:0005829; GO:0005856; GO:0007015; GO:0007568; GO:0008022; GO:0008157; GO:0010976; GO:0014069; GO:0015629; GO:0019722; GO:0019901; GO:0019904; GO:0030027; GO:0030175; GO:0030425; GO:0030426; GO:0030833; GO:0030864; GO:0031175; GO:0031594; GO:0042802; GO:0043005; GO:0043025; GO:0043197; GO:0044325; GO:0044326; GO:0044877; GO:0045202; GO:0045860; GO:0048666; GO:0050804; GO:0051015; GO:0051020; GO:0051489; GO:0051497; GO:0051823; GO:0051963; GO:0060079; GO:0060999; GO:0061001; GO:0097237; GO:0098871; GO:0098974; GO:0098978; GO:1900272; GO:1900454; GO:1904049; GO:1990761 350 XM_029346377.2 12 1 12 11 3 NA NA NA NA NA NA 351 XM_029356960.2 371 141 177 252 197 Q9WVQ1 7.11e-155 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Activin receptor-interacting protein 1) (Acvrip1) (Atrophin-1-interacting protein 1) (AIP-1) (Membrane-associated guanylate kinase inverted 2) (MAGI-2) Mus musculus (Mouse) cellular response to nerve growth factor stimulus [GO:1990090]; clathrin-dependent endocytosis [GO:0072583]; negative regulation of activin receptor signaling pathway [GO:0032926]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein kinase B signaling [GO:0051898]; nerve growth factor signaling pathway [GO:0038180]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; podocyte development [GO:0072015]; positive regulation of neuron projection development [GO:0010976]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of receptor internalization [GO:0002092]; positive regulation of synaptic vesicle clustering [GO:2000809]; receptor clustering [GO:0043113]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of synaptic membrane adhesion [GO:0099179]; signal transduction [GO:0007165]; SMAD protein signal transduction [GO:0060395] GO:0001750; GO:0001917; GO:0002092; GO:0005634; GO:0005737; GO:0005770; GO:0005814; GO:0005886; GO:0005911; GO:0005923; GO:0007165; GO:0008285; GO:0010976; GO:0014069; GO:0019894; GO:0019902; GO:0030159; GO:0030336; GO:0030425; GO:0031697; GO:0032516; GO:0032926; GO:0032991; GO:0036057; GO:0038180; GO:0043113; GO:0044877; GO:0045202; GO:0046332; GO:0048471; GO:0051898; GO:0060395; GO:0070697; GO:0070699; GO:0072015; GO:0072583; GO:0097118; GO:0097546; GO:0098696; GO:0098879; GO:0098890; GO:0098919; GO:0098978; GO:0098982; GO:0099179; GO:1990090; GO:2000809 352 XM_029356960.2 371 141 177 252 197 Q9WVQ1 7.45e-46 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Activin receptor-interacting protein 1) (Acvrip1) (Atrophin-1-interacting protein 1) (AIP-1) (Membrane-associated guanylate kinase inverted 2) (MAGI-2) Mus musculus (Mouse) cellular response to nerve growth factor stimulus [GO:1990090]; clathrin-dependent endocytosis [GO:0072583]; negative regulation of activin receptor signaling pathway [GO:0032926]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein kinase B signaling [GO:0051898]; nerve growth factor signaling pathway [GO:0038180]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; podocyte development [GO:0072015]; positive regulation of neuron projection development [GO:0010976]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of receptor internalization [GO:0002092]; positive regulation of synaptic vesicle clustering [GO:2000809]; receptor clustering [GO:0043113]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of synaptic membrane adhesion [GO:0099179]; signal transduction [GO:0007165]; SMAD protein signal transduction [GO:0060395] GO:0001750; GO:0001917; GO:0002092; GO:0005634; GO:0005737; GO:0005770; GO:0005814; GO:0005886; GO:0005911; GO:0005923; GO:0007165; GO:0008285; GO:0010976; GO:0014069; GO:0019894; GO:0019902; GO:0030159; GO:0030336; GO:0030425; GO:0031697; GO:0032516; GO:0032926; GO:0032991; GO:0036057; GO:0038180; GO:0043113; GO:0044877; GO:0045202; GO:0046332; GO:0048471; GO:0051898; GO:0060395; GO:0070697; GO:0070699; GO:0072015; GO:0072583; GO:0097118; GO:0097546; GO:0098696; GO:0098879; GO:0098890; GO:0098919; GO:0098978; GO:0098982; GO:0099179; GO:1990090; GO:2000809 353 XM_044322056.1 9 191 51 96 54 P35400 2.75e-34 Metabotropic glutamate receptor 7 (mGluR7) Rattus norvegicus (Rat) adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway [GO:0007196]; adult behavior [GO:0030534]; associative learning [GO:0008306]; axon development [GO:0061564]; behavioral fear response [GO:0001662]; chemical synaptic transmission [GO:0007268]; conditioned taste aversion [GO:0001661]; G protein-coupled glutamate receptor signaling pathway [GO:0007216]; glycosylation [GO:0070085]; learning or memory [GO:0007611]; memory [GO:0007613]; multicellular organismal response to stress [GO:0033555]; negative regulation of glutamate secretion [GO:0014050]; negative regulation of neuron apoptotic process [GO:0043524]; nervous system process [GO:0050877]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of synaptic vesicle exocytosis [GO:2000300]; sensory perception of sound [GO:0007605]; short-term memory [GO:0007614]; transmission of nerve impulse [GO:0019226] GO:0001640; GO:0001642; GO:0001661; GO:0001662; GO:0005245; GO:0005246; GO:0005516; GO:0005791; GO:0005794; GO:0005886; GO:0005938; GO:0007196; GO:0007216; GO:0007268; GO:0007605; GO:0007611; GO:0007613; GO:0007614; GO:0008066; GO:0008306; GO:0009986; GO:0010855; GO:0014050; GO:0016020; GO:0016595; GO:0019226; GO:0030165; GO:0030424; GO:0030425; GO:0030534; GO:0032279; GO:0032991; GO:0033555; GO:0042734; GO:0042802; GO:0043025; GO:0043195; GO:0043198; GO:0043235; GO:0043524; GO:0043679; GO:0045202; GO:0045211; GO:0046983; GO:0048306; GO:0048786; GO:0048787; GO:0050877; GO:0051966; GO:0061564; GO:0070085; GO:0070905; GO:0098793; GO:0098978; GO:0098982; GO:0099171; GO:2000300 354 XR_006396453.1 0 11 0 0 0 NA NA NA NA NA NA 355 XM_044315363.1 0 0 4 0 9 NA NA NA NA NA NA 356 XM_029355377.2 23 0 0 35 0 Q5RFG8 8.05e-23 E3 ubiquitin-protein ligase E3D (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase E3D) (UbcH10-binding protein with a HECT-like domain) (Ubiquitin-conjugating enzyme E2C-binding protein) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) protein ubiquitination [GO:0016567] GO:0005737; GO:0016567; GO:0016740 357 XM_029344849.2 218 378 28 150 276 P58912 3.31e-69 DELTA-alicitoxin-Pse2b (DELTA-ALTX-Pse2b) (Toxin PsTX-60B) (PTX60B) Phyllodiscus semoni (Night anemone) hemolysis in another organism [GO:0044179] GO:0005576; GO:0042151; GO:0044179; GO:0090729 358 XM_044323236.1 891 641 445 888 924 Q96JG6 0 Syndetin (Coiled-coil domain-containing protein 132) (EARP/GARPII complex subunit VPS50) Homo sapiens (Human) endocytic recycling [GO:0032456]; protein transport [GO:0015031] GO:0000149; GO:0015031; GO:0016020; GO:0032456; GO:0048471; GO:0055037; GO:0070062; GO:1990745 359 XM_044314564.1 524 328 100 625 123 E7FAM5 6.45e-55 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 360 XM_029349453.2 14 0 0 0 6 P54833 1.7e-21 Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor) Canis lupus familiaris (Dog) (Canis familiaris) activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; desensitization of G protein-coupled receptor signaling pathway by arrestin [GO:0002032]; negative regulation of smooth muscle contraction [GO:0045986]; norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0002025]; positive regulation of autophagosome maturation [GO:1901098]; positive regulation of lipophagy [GO:1904504]; positive regulation of MAPK cascade [GO:0043410]; receptor-mediated endocytosis [GO:0006898] GO:0002025; GO:0002032; GO:0004930; GO:0004941; GO:0005769; GO:0005794; GO:0005886; GO:0006898; GO:0007190; GO:0042803; GO:0043235; GO:0043410; GO:0045986; GO:0051380; GO:0071880; GO:1901098; GO:1904504 361 XM_029354732.2 1385 1350 503 366 552 NA NA NA NA NA NA 362 XM_029338431.2 5922 4242 3082 6399 5962 Q5ZML3 1.98e-61 Serine/arginine-rich splicing factor 1 (Splicing factor, arginine/serine-rich 1) Gallus gallus (Chicken) alternative mRNA splicing, via spliceosome [GO:0000380]; mRNA splicing, via spliceosome [GO:0000398] GO:0000380; GO:0000398; GO:0003723; GO:0005737; GO:0016607 363 XM_029346871.2 959 640 381 1253 991 Q8R2S1 2.06e-74 Ribosomal protein S6 kinase-like 1 (EC 2.7.11.1) Mus musculus (Mouse) protein phosphorylation [GO:0006468] GO:0004674; GO:0005524; GO:0005840; GO:0006468; GO:0106310; GO:1990904 364 XM_029351031.2 3501 2465 2667 3659 3817 Q4KMZ8 2.07e-49 Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1 (Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein 1) (Protein FAM77C) Homo sapiens (Human) regulation of sodium ion transport [GO:0002028] GO:0002028; GO:0005886; GO:0051117 365 XM_029325699.2 21 1255 69 742 84 Q76DT2 4.66e-91 DELTA-thalatoxin-Avl2a (DELTA-TATX-Avl2a) (Toxin AvTX-60A) (Av60A) Actineria villosa (Okinawan sea anemone) hemolysis in another organism [GO:0044179] GO:0005576; GO:0042151; GO:0044179; GO:0090729 366 XM_044311070.1 18 28 3 149 151 NA NA NA NA NA NA 367 XM_044325049.1 41 2 51 3 99 NA NA NA NA NA NA 368 XM_044327999.1 1439 1249 845 1686 1339 NA NA NA NA NA NA 369 XM_029326920.2 1473 1366 877 1420 1213 P57737 0 Coronin-7 (Crn7) (70 kDa WD repeat tumor rejection antigen homolog) Homo sapiens (Human) actin filament organization [GO:0007015]; actin filament polymerization [GO:0030041]; cell migration [GO:0016477]; establishment of cell polarity [GO:0030010]; Golgi organization [GO:0007030]; Golgi to endosome transport [GO:0006895]; positive regulation of hippo signaling [GO:0035332]; protein transport [GO:0015031] GO:0000139; GO:0003779; GO:0005794; GO:0005802; GO:0005829; GO:0006895; GO:0007015; GO:0007030; GO:0015031; GO:0016020; GO:0016477; GO:0030010; GO:0030041; GO:0031410; GO:0035332; GO:0051015 370 XR_006398001.1 54 76 93 68 193 NA NA NA NA NA NA 371 XM_044327028.1 333 125 120 399 238 Q8K4F6 7.46e-123 28S rRNA (cytosine-C(5))-methyltransferase (EC 2.1.1.-) (NOL1/NOP2/Sun domain family member 5) (Williams-Beuren syndrome chromosomal region 20A protein homolog) Mus musculus (Mouse) cerebral cortex development [GO:0021987]; cognition [GO:0050890]; corpus callosum development [GO:0022038]; oligodendrocyte development [GO:0014003]; positive regulation of translation [GO:0045727]; regulation of myelination [GO:0031641]; RNA methylation [GO:0001510]; rRNA base methylation [GO:0070475] GO:0001510; GO:0003723; GO:0005654; GO:0005730; GO:0009383; GO:0014003; GO:0021987; GO:0022038; GO:0031641; GO:0045727; GO:0050890; GO:0070475 372 XM_044309565.1 27 32 63 38 127 NA NA NA NA NA NA 373 XM_044329315.1 0 3 3 29 27 NA NA NA NA NA NA 374 XM_044326849.1 48 28 44 47 5 NA NA NA NA NA NA 375 XM_044311280.1 0 0 1 0 6 NA NA NA NA NA NA 376 XM_029339540.2 1341 1194 803 1304 771 Q28C69 2.43e-89 Enolase-phosphatase E1 (EC 3.1.3.77) (2,3-diketo-5-methylthio-1-phosphopentane phosphatase) (MASA homolog) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284] GO:0000287; GO:0005634; GO:0005737; GO:0019284; GO:0019509; GO:0043715; GO:0043716; GO:0043874 377 XM_044322099.1 1184 2605 1078 443 117 P55112 3.55e-42 Zinc metalloproteinase nas-4 (EC 3.4.24.-) (Nematode astacin 4) Caenorhabditis elegans proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0006508; GO:0008270 378 XM_044314373.1 31 0 26 0 263 P07949 6.59e-78 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; axon guidance [GO:0007411]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; lymphocyte migration into lymphoid organs [GO:0097021]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; posterior midgut development [GO:0007497]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006468; GO:0006919; GO:0007156; GO:0007158; GO:0007165; GO:0007169; GO:0007411; GO:0007497; GO:0009410; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0038023; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0097021; GO:0098797; GO:2001241 379 XM_044309551.1 24 0 22 3 19 NA NA NA NA NA NA 380 XM_044313546.1 13 415 232 84 36 Q9JM13 1.34e-79 Rab5 GDP/GTP exchange factor (Rabex-5) Mus musculus (Mouse) dendritic transport [GO:0098935]; establishment of localization in cell [GO:0051649]; Kit signaling pathway [GO:0038109]; mast cell degranulation [GO:0043303]; mast cell migration [GO:0097531]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of Kit signaling pathway [GO:1900235]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of mast cell activation [GO:0033004]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; negative regulation of receptor-mediated endocytosis [GO:0048261]; protein phosphorylation [GO:0006468]; protein targeting to membrane [GO:0006612]; Ras protein signal transduction [GO:0007265]; receptor-mediated endocytosis [GO:0006898]; regulation of Fc receptor mediated stimulatory signaling pathway [GO:0060368] GO:0001933; GO:0002686; GO:0003677; GO:0005085; GO:0005730; GO:0005769; GO:0005829; GO:0006468; GO:0006612; GO:0006898; GO:0007265; GO:0008270; GO:0030139; GO:0030425; GO:0031267; GO:0031982; GO:0032715; GO:0032764; GO:0033004; GO:0038109; GO:0043303; GO:0043305; GO:0046580; GO:0048261; GO:0050728; GO:0051649; GO:0055037; GO:0060368; GO:0061630; GO:0097531; GO:0098935; GO:1900235 381 XM_029337989.2 1915 1267 937 1173 809 Q4R4R9 2.21e-49 Ras-related protein Rab-3A Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) exocytosis [GO:0006887]; protein transport [GO:0015031] GO:0003924; GO:0005525; GO:0005764; GO:0005829; GO:0005886; GO:0006887; GO:0015031; GO:0030133; GO:0030424; GO:0048786; GO:0098793; GO:0098794 382 XM_044307763.1 17 45 22 48 25 A0JNI8 4.71e-98 LIM/homeobox protein Lhx9 (LIM homeobox protein 9) Bos taurus (Bovine) dorsal spinal cord interneuron anterior axon guidance [GO:0097380]; negative regulation of DNA-templated transcription [GO:0045892]; neuron differentiation [GO:0030182]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000977; GO:0000981; GO:0005634; GO:0006357; GO:0030182; GO:0045892; GO:0046872; GO:0097380 383 XM_044317724.1 87 0 118 0 0 NA NA NA NA NA NA 384 XM_044321149.1 0 0 0 65 0 Q9NYT0 1.16e-45 Pleckstrin-2 Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; intracellular signal transduction [GO:0035556]; positive regulation of plasma membrane bounded cell projection assembly [GO:0120034] GO:0005737; GO:0005856; GO:0005886; GO:0031258; GO:0031532; GO:0032266; GO:0035556; GO:0043325; GO:0080025; GO:0120034 385 XM_029331480.2 0 0 41 44 13 Q14839 0 Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC 3.6.4.12) (ATP-dependent helicase CHD4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta) Homo sapiens (Human) chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone deacetylation [GO:0016575]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of cell fate specification [GO:0042659]; regulation of stem cell differentiation [GO:2000736]; regulation of synapse assembly [GO:0051963]; terminal button organization [GO:0072553] GO:0000122; GO:0000724; GO:0000781; GO:0000785; GO:0001221; GO:0003677; GO:0003682; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0006338; GO:0008270; GO:0010629; GO:0016020; GO:0016575; GO:0016581; GO:0016887; GO:0032991; GO:0042393; GO:0042659; GO:0042826; GO:0045892; GO:0045893; GO:0051963; GO:0061629; GO:0072553; GO:0090575; GO:0090734; GO:0140658; GO:0150048; GO:2000736 386 XM_029331480.2 0 0 41 44 13 Q14839 2.51e-59 Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC 3.6.4.12) (ATP-dependent helicase CHD4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta) Homo sapiens (Human) chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone deacetylation [GO:0016575]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of cell fate specification [GO:0042659]; regulation of stem cell differentiation [GO:2000736]; regulation of synapse assembly [GO:0051963]; terminal button organization [GO:0072553] GO:0000122; GO:0000724; GO:0000781; GO:0000785; GO:0001221; GO:0003677; GO:0003682; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0006338; GO:0008270; GO:0010629; GO:0016020; GO:0016575; GO:0016581; GO:0016887; GO:0032991; GO:0042393; GO:0042659; GO:0042826; GO:0045892; GO:0045893; GO:0051963; GO:0061629; GO:0072553; GO:0090575; GO:0090734; GO:0140658; GO:0150048; GO:2000736 387 XR_006397404.1 0 0 11 0 5 NA NA NA NA NA NA 388 XR_006396909.1 215 0 169 123 49 NA NA NA NA NA NA 389 XM_029330995.2 535 504 350 589 435 NA NA NA NA NA NA 390 XM_029343299.2 452 140 236 303 219 Q501V0 1.86e-138 Serine/threonine-protein kinase H1 homolog (EC 2.7.11.1) Danio rerio (Zebrafish) (Brachydanio rerio) protein phosphorylation [GO:0006468] GO:0004674; GO:0005524; GO:0006468; GO:0106310 391 XM_044320992.1 898 691 351 849 869 O15050 0 TPR and ankyrin repeat-containing protein 1 (Lupus brain antigen 1 homolog) Homo sapiens (Human) NA NA 392 XM_029329658.2 128 155 66 146 157 NA NA NA NA NA NA 393 XM_029331482.2 79 389 179 91 509 Q6PDQ2 0 Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC 3.6.4.12) Mus musculus (Mouse) chromatin remodeling [GO:0006338]; histone deacetylation [GO:0016575]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of cell fate specification [GO:0042659]; regulation of stem cell differentiation [GO:2000736]; regulation of synapse assembly [GO:0051963]; terminal button organization [GO:0072553] GO:0000122; GO:0000781; GO:0000785; GO:0001221; GO:0003677; GO:0003682; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0006338; GO:0010629; GO:0016575; GO:0016581; GO:0016887; GO:0032991; GO:0032993; GO:0042393; GO:0042659; GO:0042826; GO:0045892; GO:0045893; GO:0046872; GO:0051963; GO:0061629; GO:0072553; GO:0090575; GO:0140297; GO:0140658; GO:0150048; GO:2000736 394 XM_029331482.2 79 389 179 91 509 Q6PDQ2 1.97e-59 Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC 3.6.4.12) Mus musculus (Mouse) chromatin remodeling [GO:0006338]; histone deacetylation [GO:0016575]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of cell fate specification [GO:0042659]; regulation of stem cell differentiation [GO:2000736]; regulation of synapse assembly [GO:0051963]; terminal button organization [GO:0072553] GO:0000122; GO:0000781; GO:0000785; GO:0001221; GO:0003677; GO:0003682; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0006338; GO:0010629; GO:0016575; GO:0016581; GO:0016887; GO:0032991; GO:0032993; GO:0042393; GO:0042659; GO:0042826; GO:0045892; GO:0045893; GO:0046872; GO:0051963; GO:0061629; GO:0072553; GO:0090575; GO:0140297; GO:0140658; GO:0150048; GO:2000736 395 XR_003825087.2 0 0 0 0 6 NA NA NA NA NA NA 396 XM_044322932.1 24 16 12 0 17 NA NA NA NA NA NA 397 XM_044323539.1 1146 620 615 642 990 Q9DBQ9 4.94e-45 Transcriptional protein SWT1 Mus musculus (Mouse) NA GO:0005634 398 XM_044322944.1 0 0 0 0 124 NA NA NA NA NA NA 399 XM_044326754.1 405 295 130 149 235 NA NA NA NA NA NA 400 XM_029348496.2 61 0 33 74 49 NA NA NA NA NA NA 401 XM_044311907.1 28 14 18 24 9 NA NA NA NA NA NA 402 XM_029326046.2 45 12 18 27 12 NA NA NA NA NA NA 403 XR_006393019.1 40 157 36 2 135 NA NA NA NA NA NA 404 XM_029345989.2 3881 3655 1351 1048 735 NA NA NA NA NA NA 405 XM_044313452.1 10 0 0 0 0 NA NA NA NA NA NA 406 XM_029333305.2 229 121 76 213 204 NA NA NA NA NA NA 407 XM_044316659.1 502 305 201 339 562 NA NA NA NA NA NA 408 XM_029355683.2 404 704 402 211 297 Q9V9W8 1.12e-24 Protein pygopus (Protein gammy legs) Drosophila melanogaster (Fruit fly) canonical Wnt signaling pathway [GO:0060070]; chitin-based larval cuticle pattern formation [GO:0035293]; delamination [GO:0060232]; embryonic pattern specification [GO:0009880]; eye-antennal disc development [GO:0035214]; imaginal disc-derived wing expansion [GO:0048526]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; segment polarity determination [GO:0007367]; wing disc morphogenesis [GO:0007472] GO:0003713; GO:0005634; GO:0005654; GO:0006357; GO:0007367; GO:0007472; GO:0009880; GO:0035064; GO:0035214; GO:0035293; GO:0045944; GO:0046872; GO:0048526; GO:0060070; GO:0060232; GO:1990907 409 XM_029337825.2 370 741 655 388 189 NA NA NA NA NA NA 410 XR_006394101.1 144 77 98 324 283 NA NA NA NA NA NA 411 XM_029343792.2 2929 2086 1209 2769 2919 A0A2R8QP51 0 NA NA NA NA 412 XM_044326897.1 13 2 3 14 82 NA NA NA NA NA NA 413 XM_029327372.2 1956 1454 680 1133 685 P52747 3.97e-120 Zinc finger protein 143 (SPH-binding factor) (Selenocysteine tRNA gene transcription-activating factor) (hStaf) Homo sapiens (Human) positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of snRNA transcription by RNA polymerase II [GO:1905382]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription by RNA polymerase III [GO:0045945]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription by RNA polymerase III [GO:0006359] GO:0000978; GO:0000981; GO:0001228; GO:0003682; GO:0005654; GO:0006355; GO:0006357; GO:0006359; GO:0045944; GO:0045945; GO:0046872; GO:0048661; GO:1905382 414 XM_029327372.2 1956 1454 680 1133 685 P52747 1.34e-59 Zinc finger protein 143 (SPH-binding factor) (Selenocysteine tRNA gene transcription-activating factor) (hStaf) Homo sapiens (Human) positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of snRNA transcription by RNA polymerase II [GO:1905382]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription by RNA polymerase III [GO:0045945]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription by RNA polymerase III [GO:0006359] GO:0000978; GO:0000981; GO:0001228; GO:0003682; GO:0005654; GO:0006355; GO:0006357; GO:0006359; GO:0045944; GO:0045945; GO:0046872; GO:0048661; GO:1905382 415 XM_044328139.1 77 51 0 88 69 NA NA NA NA NA NA 416 XR_006391356.1 497 317 453 653 711 Q99698 0 Lysosomal-trafficking regulator (Beige homolog) Homo sapiens (Human) defense response to bacterium [GO:0042742]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; leukocyte chemotaxis [GO:0030595]; mast cell secretory granule organization [GO:0033364]; melanosome organization [GO:0032438]; natural killer cell mediated cytotoxicity [GO:0042267]; phagocytosis [GO:0006909]; pigmentation [GO:0043473]; protein localization [GO:0008104]; protein transport [GO:0015031] GO:0005829; GO:0006909; GO:0008104; GO:0015031; GO:0015630; GO:0016020; GO:0019901; GO:0030595; GO:0032438; GO:0032510; GO:0033364; GO:0042267; GO:0042742; GO:0042832; GO:0043473; GO:0051607 417 XR_006391356.1 497 317 453 653 711 Q99698 4.36e-48 Lysosomal-trafficking regulator (Beige homolog) Homo sapiens (Human) defense response to bacterium [GO:0042742]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; leukocyte chemotaxis [GO:0030595]; mast cell secretory granule organization [GO:0033364]; melanosome organization [GO:0032438]; natural killer cell mediated cytotoxicity [GO:0042267]; phagocytosis [GO:0006909]; pigmentation [GO:0043473]; protein localization [GO:0008104]; protein transport [GO:0015031] GO:0005829; GO:0006909; GO:0008104; GO:0015031; GO:0015630; GO:0016020; GO:0019901; GO:0030595; GO:0032438; GO:0032510; GO:0033364; GO:0042267; GO:0042742; GO:0042832; GO:0043473; GO:0051607 418 XM_044312807.1 0 25 0 0 0 Q17RS7 3.87e-68 Flap endonuclease GEN homolog 1 (EC 3.1.-.-) Homo sapiens (Human) double-strand break repair via homologous recombination [GO:0000724]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; regulation of centrosome duplication [GO:0010824]; replication fork processing [GO:0031297]; resolution of mitotic recombination intermediates [GO:0071140]; resolution of recombination intermediates [GO:0071139] GO:0000287; GO:0000400; GO:0000724; GO:0005654; GO:0005813; GO:0008821; GO:0010824; GO:0017108; GO:0031297; GO:0042803; GO:0071139; GO:0071140; GO:0090267 419 XM_029351962.2 26165 11915 13168 20557 11170 P29773 3.12e-36 Protein C-ets-2 Lytechinus variegatus (Green sea urchin) (Echinus variegatus) regulation of transcription by RNA polymerase II [GO:0006357] GO:0003700; GO:0005634; GO:0006357; GO:0043565 420 XM_029329998.2 165 469 20 1199 143 NA NA NA NA NA NA 421 XM_029327174.2 176 11 49 227 154 O54853 2.95e-107 Potassium voltage-gated channel subfamily H member 6 (Ether-a-go-go-related gene potassium channel 2) (ERG-2) (Eag-related protein 2) (Ether-a-go-go-related protein 2) (Voltage-gated potassium channel subunit Kv11.2) Rattus norvegicus (Rat) membrane repolarization during action potential [GO:0086011]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307] GO:0005242; GO:0005249; GO:0005267; GO:0005886; GO:0006813; GO:0034765; GO:0042391; GO:0044877; GO:0060307; GO:0071805; GO:0086011; GO:0086091 422 XR_003827555.2 17 0 0 23 28 NA NA NA NA NA NA 423 XR_003826937.2 29 1 21 6 78 Q5DTW2 5.84e-21 Scm-like with four MBT domains protein 2 Mus musculus (Mouse) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629] GO:0003682; GO:0003714; GO:0005634; GO:0005654; GO:0005829; GO:0010629; GO:0016235; GO:0016604; GO:0016607; GO:0042393; GO:0043231; GO:0045892 424 XR_003826937.2 29 1 21 6 78 Q5DTW2 5.84e-21 Scm-like with four MBT domains protein 2 Mus musculus (Mouse) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629] GO:0003682; GO:0003714; GO:0005634; GO:0005654; GO:0005829; GO:0010629; GO:0016235; GO:0016604; GO:0016607; GO:0042393; GO:0043231; GO:0045892 425 XM_044316968.1 77 60 89 477 281 Q7SXV2 3.11e-49 Zinc finger protein AEBP2 (Adipocyte enhancer-binding protein 2 homolog) (AE-binding protein 2 homolog) Danio rerio (Zebrafish) (Brachydanio rerio) chromatin organization [GO:0006325]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0003677; GO:0006325; GO:0006357; GO:0035098; GO:0046872 426 XM_044313513.1 444 473 205 367 587 P32929 8.76e-168 Cystathionine gamma-lyase (CGL) (CSE) (EC 4.4.1.1) (Cysteine desulfhydrase) (Cysteine-protein sulfhydrase) (Gamma-cystathionase) (Homocysteine desulfhydrase) (EC 4.4.1.2) Homo sapiens (Human) cellular response to leukemia inhibitory factor [GO:1990830]; cysteine biosynthetic process [GO:0019344]; cysteine biosynthetic process via cystathionine [GO:0019343]; cysteine metabolic process [GO:0006534]; endoplasmic reticulum unfolded protein response [GO:0030968]; hydrogen sulfide biosynthetic process [GO:0070814]; lipid metabolic process [GO:0006629]; negative regulation of apoptotic signaling pathway [GO:2001234]; positive regulation of aortic smooth muscle cell differentiation [GO:1904831]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein homotetramerization [GO:0051289]; protein sulfhydration [GO:0044524]; protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine [GO:0018272]; transsulfuration [GO:0019346] GO:0004123; GO:0005516; GO:0005737; GO:0005829; GO:0006534; GO:0006629; GO:0016846; GO:0018272; GO:0019343; GO:0019344; GO:0019346; GO:0030170; GO:0030968; GO:0042802; GO:0043123; GO:0044524; GO:0044540; GO:0047982; GO:0051092; GO:0051289; GO:0070062; GO:0070814; GO:0080146; GO:0098606; GO:1904831; GO:1990830; GO:2001234 427 XM_029336808.2 1512 1138 743 1063 1060 Q9UKP5 3.36e-129 A disintegrin and metalloproteinase with thrombospondin motifs 6 (ADAM-TS 6) (ADAM-TS6) (ADAMTS-6) (EC 3.4.24.-) Homo sapiens (Human) aorta development [GO:0035904]; cardiac septum development [GO:0003279]; coronary vasculature development [GO:0060976]; extracellular matrix organization [GO:0030198]; kidney development [GO:0001822]; proteolysis [GO:0006508] GO:0001822; GO:0003279; GO:0004222; GO:0005576; GO:0006508; GO:0008237; GO:0030198; GO:0031012; GO:0035904; GO:0046872; GO:0060976 428 XM_029336808.2 1512 1138 743 1063 1060 Q9UKP5 1.5e-27 A disintegrin and metalloproteinase with thrombospondin motifs 6 (ADAM-TS 6) (ADAM-TS6) (ADAMTS-6) (EC 3.4.24.-) Homo sapiens (Human) aorta development [GO:0035904]; cardiac septum development [GO:0003279]; coronary vasculature development [GO:0060976]; extracellular matrix organization [GO:0030198]; kidney development [GO:0001822]; proteolysis [GO:0006508] GO:0001822; GO:0003279; GO:0004222; GO:0005576; GO:0006508; GO:0008237; GO:0030198; GO:0031012; GO:0035904; GO:0046872; GO:0060976 429 XM_044315041.1 56 23 32 48 51 NA NA NA NA NA NA 430 XM_044320052.1 48 22 20 23 42 Q09575 6.82e-29 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 431 XM_044320052.1 48 22 20 23 42 Q09575 6.82e-29 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 432 XM_044328595.1 113 15 0 0 0 C6FG12 1.18e-23 Protein NLRC5 Ictalurus punctatus (Channel catfish) (Silurus punctatus) innate immune response [GO:0045087] GO:0005524; GO:0005737; GO:0045087 433 XM_044310407.1 95 31 96 104 360 NA NA NA NA NA NA 434 XR_006397314.1 18 7 18 23 3 NA NA NA NA NA NA 435 XM_044317513.1 3 7 2 8 74 P34456 2.72e-26 Uncharacterized protein F54H12.2 Caenorhabditis elegans deoxyribonucleotide biosynthetic process [GO:0009263] GO:0004748; GO:0005829; GO:0009263 436 XM_044319274.1 85 7 2 7 1 NA NA NA NA NA NA 437 XM_044314549.1 32 20 22 47 21 NA NA NA NA NA NA 438 XM_029345837.2 75 48 27 124 66 Q8AV28 1.53e-80 Pericentriolar material 1 protein (PCM-1) Gallus gallus (Chicken) centrosome cycle [GO:0007098]; cilium assembly [GO:0060271]; intraciliary transport involved in cilium assembly [GO:0035735]; microtubule anchoring at centrosome [GO:0034454]; positive regulation of intracellular protein transport [GO:0090316]; protein localization to centrosome [GO:0071539] GO:0005737; GO:0005813; GO:0005814; GO:0007098; GO:0034451; GO:0034454; GO:0035735; GO:0036064; GO:0060271; GO:0071539; GO:0090316 439 XM_044314985.1 0 4 0 15 0 NA NA NA NA NA NA 440 XR_006391816.1 226 259 201 300 161 NA NA NA NA NA NA 441 XR_006395621.1 9 9 12 16 14 NA NA NA NA NA NA 442 XM_029330056.2 65 3 29 2 50 NA NA NA NA NA NA 443 XM_029345406.2 27 10 8 0 0 Q9CYL5 2.16e-23 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Mus musculus (Mouse) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070374 444 XM_044307711.1 0 0 31 122 31 NA NA NA NA NA NA 445 XM_044326468.1 8 0 14 112 51 NA NA NA NA NA NA 446 XM_029343575.2 2 453 0 13 836 Q7LBC6 1.32e-145 Lysine-specific demethylase 3B (EC 1.14.11.65) (JmjC domain-containing histone demethylation protein 2B) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA) ([histone H3]-dimethyl-L-lysine(9) demethylase 3B) Homo sapiens (Human) chromatin organization [GO:0006325]; histone H3-K9 demethylation [GO:0033169]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000118; GO:0000785; GO:0003712; GO:0005654; GO:0006325; GO:0006357; GO:0031490; GO:0032454; GO:0033169; GO:0046872; GO:0140683 447 XM_029343575.2 2 453 0 13 836 Q7LBC6 4.45e-46 Lysine-specific demethylase 3B (EC 1.14.11.65) (JmjC domain-containing histone demethylation protein 2B) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA) ([histone H3]-dimethyl-L-lysine(9) demethylase 3B) Homo sapiens (Human) chromatin organization [GO:0006325]; histone H3-K9 demethylation [GO:0033169]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000118; GO:0000785; GO:0003712; GO:0005654; GO:0006325; GO:0006357; GO:0031490; GO:0032454; GO:0033169; GO:0046872; GO:0140683 448 XM_029326691.2 931 3123 1431 4526 5321 R1CW23 6.87e-101 Dimethylsulfonioproprionate lyase 7 (DMSP lyase 7) (EC 4.4.1.3) (Dimethylpropiothetin dethiomethylase 7) Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi) NA GO:0047869 449 XM_029339567.2 280 85 150 101 148 Q80T85 5.81e-134 DDB1- and CUL4-associated factor 5 (WD repeat-containing protein 22) Mus musculus (Mouse) protein ubiquitination [GO:0016567] GO:0005634; GO:0005737; GO:0005739; GO:0016567; GO:0080008 450 XR_006391932.1 6 0 2 0 4 NA NA NA NA NA NA 451 XM_029338610.2 774 302 310 368 365 Q2XWK0 1.08e-132 Synaptic vesicle 2-related protein (SV2-related protein) Xenopus laevis (African clawed frog) NA GO:0022857; GO:0030672 452 XM_029323531.2 45 3 25 11 22 NA NA NA NA NA NA 453 XM_029357706.2 26 0 0 0 0 NA NA NA NA NA NA 454 XM_029325321.2 58 130 91 109 155 NA NA NA NA NA NA 455 XM_044313590.1 2 5 5 1 19 NA NA NA NA NA NA 456 XR_003827495.2 13 0 7 0 13 NA NA NA NA NA NA 457 XM_029335759.2 145 34 10 104 23 Q99ME2 3.32e-111 WD repeat-containing protein 6 (mWDR6) Mus musculus (Mouse) G1 to G0 transition [GO:0070314]; negative regulation of autophagy [GO:0010507]; negative regulation of cell population proliferation [GO:0008285]; tRNA methylation [GO:0030488] GO:0005737; GO:0005829; GO:0005886; GO:0008180; GO:0008285; GO:0010507; GO:0030488; GO:0032991; GO:0043560; GO:0070314 458 XM_044317272.1 10 1 25 20 11 Q91770 1.33e-22 Homeobox protein not2 (Xnot-2) (Xnot2) Xenopus laevis (African clawed frog) negative regulation of DNA-templated transcription [GO:0045892]; notochord formation [GO:0014028] GO:0000981; GO:0003677; GO:0005634; GO:0014028; GO:0045892 459 XR_006392094.1 17 57 0 27 14 NA NA NA NA NA NA 460 XM_029327250.2 138 124 58 127 109 NA NA NA NA NA NA 461 XM_029358686.2 0 0 0 25 0 P83038 0 Histone deacetylase 4 (HD4) (EC 3.5.1.98) Gallus gallus (Chicken) B cell activation [GO:0042113]; B cell differentiation [GO:0030183]; chromatin organization [GO:0006325]; histone deacetylation [GO:0016575]; histone H4 deacetylation [GO:0070933]; inflammatory response [GO:0006954]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of striated muscle tissue development [GO:0045843]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399] GO:0000118; GO:0000122; GO:0004407; GO:0005737; GO:0006325; GO:0006954; GO:0007399; GO:0016575; GO:0030183; GO:0042113; GO:0045843; GO:0045892; GO:0046872; GO:0070933; GO:0140297 462 XM_044311434.1 17 0 13 0 29 NA NA NA NA NA NA 463 XM_029346407.2 651 407 338 371 559 NA NA NA NA NA NA 464 XM_029345949.2 526 176 232 402 684 NA NA NA NA NA NA 465 XM_029339490.2 0 83 0 69 62 NA NA NA NA NA NA 466 XM_044318093.1 15 0 13 1 34 NA NA NA NA NA NA 467 XM_029326882.2 30 0 6 18 11 NA NA NA NA NA NA 468 XM_044313971.1 0 2 0 6 38 NA NA NA NA NA NA 469 XM_044327142.1 0 0 0 0 6 B3EWZ3 2.71e-35 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 470 XM_029343798.2 263 0 52 259 0 Q2LE78 8.95e-63 BTB/POZ domain-containing protein 6 Xenopus laevis (African clawed frog) NA GO:0005737 471 XM_029329452.2 3416 5007 3558 3922 3187 NA NA NA NA NA NA 472 XR_003824522.2 1 3 5 1 17 NA NA NA NA NA NA 473 XR_006393464.1 31 7 9 12 84 NA NA NA NA NA NA 474 XM_029332707.2 172 101 75 130 114 Q28HM1 1.21e-86 Dimethyladenosine transferase 1, mitochondrial (EC 2.1.1.-) (Mitochondrial 12S rRNA dimethylase 1) (Mitochondrial transcription factor B1) (mtTFB1) (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0000179; GO:0003677; GO:0003723; GO:0005739 475 XM_044311388.1 21 2 0 11 0 Q9H5F2 1.82e-25 Uncharacterized protein CFAP68 (cilia and flagella associated protein 68) Homo sapiens (Human) NA GO:0005654 476 XR_006393442.1 18 0 7 0 0 Q9HAV4 2.47e-35 Exportin-5 (Exp5) (Ran-binding protein 21) Homo sapiens (Human) miRNA metabolic process [GO:0010586]; positive regulation of post-transcriptional gene silencing by RNA [GO:1900370]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; RNA export from nucleus [GO:0006405] GO:0000049; GO:0003723; GO:0003729; GO:0005049; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006405; GO:0006611; GO:0010586; GO:0016442; GO:0031267; GO:0035281; GO:0042565; GO:0070883; GO:1900370; GO:1905172 477 XM_029336012.2 2337 1848 1286 2815 3410 P49410 1.72e-180 Elongation factor Tu, mitochondrial (EF-Tu) Bos taurus (Bovine) mitochondrial translational elongation [GO:0070125]; translational elongation [GO:0006414] GO:0003746; GO:0003924; GO:0005525; GO:0005739; GO:0005743; GO:0005759; GO:0006414; GO:0042645; GO:0070125 478 XM_029336832.2 1270 991 878 931 1012 Q9H7R5 2.84e-123 Zinc finger protein 665 (Zinc finger protein 160-like) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 479 XM_029336832.2 1270 991 878 931 1012 Q9H7R5 9.88e-117 Zinc finger protein 665 (Zinc finger protein 160-like) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 480 XM_029336832.2 1270 991 878 931 1012 Q9H7R5 1.35e-114 Zinc finger protein 665 (Zinc finger protein 160-like) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 481 XM_029336832.2 1270 991 878 931 1012 Q9H7R5 1.65e-107 Zinc finger protein 665 (Zinc finger protein 160-like) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 482 XR_003824637.2 25 29 7 26 15 A0JPI9 1.24e-48 Leucine-rich repeat-containing protein 74A (Leucine-rich repeat-containing protein 74) Rattus norvegicus (Rat) NA NA 483 XM_044315965.1 187 182 123 264 183 NA NA NA NA NA NA 484 XM_044311233.1 43 0 4 0 1 B8V7P3 1.14e-74 Putative carbonic anhydrase (EC 4.2.1.1) (Carbonate dehydratase) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0004089; GO:0005576; GO:0008270 485 XM_029350156.2 4115 4042 3100 3474 2485 Q8QG64 6.07e-61 RING-box protein 1 (Rbx1) (Hyperosmotic protein 21) (sHOP21) Salmo salar (Atlantic salmon) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein monoubiquitination [GO:0006513]; protein neddylation [GO:0045116]; protein ubiquitination [GO:0016567]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0005634; GO:0005737; GO:0006513; GO:0008270; GO:0016567; GO:0019005; GO:0031146; GO:0031463; GO:0031464; GO:0031465; GO:0031467; GO:0043161; GO:0045116; GO:0061663 486 XM_029336582.2 24 61 26 47 45 NA NA NA NA NA NA 487 XM_029349761.2 123 146 54 29 188 NA NA NA NA NA NA 488 XM_044328556.1 1513 837 806 769 760 Q6DCP5 3.12e-51 Protein saal1 Xenopus laevis (African clawed frog) NA GO:0005634 489 XM_044314213.1 45 24 18 8 58 NA NA NA NA NA NA 490 XM_044316072.1 271 63 135 292 106 Q66GV0 8.32e-50 Protein Mpv17 Xenopus laevis (African clawed frog) NA GO:0005743 491 XM_044319300.1 0 0 10 0 11 NA NA NA NA NA NA 492 XM_029357976.2 38 23 15 13 10 NA NA NA NA NA NA 493 XM_044314602.1 0 6 13 0 52 NA NA NA NA NA NA 494 XM_044317389.1 198 61 158 125 847 NA NA NA NA NA NA 495 XR_006398069.1 140 59 22 38 14 Q6Q0C0 5.62e-95 E3 ubiquitin-protein ligase TRAF7 (EC 2.3.2.27) (RING finger and WD repeat-containing protein 1) (RING finger protein 119) (RING-type E3 ubiquitin transferase TRAF7) (TNF receptor-associated factor 7) Homo sapiens (Human) apoptotic process [GO:0006915]; Notch signaling pathway [GO:0007219]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of MAPK cascade [GO:0043410]; protein ubiquitination [GO:0016567]; regulation of ERK1 and ERK2 cascade [GO:0070372]; ribosomal large subunit assembly [GO:0000027] GO:0000027; GO:0000151; GO:0004842; GO:0005730; GO:0005886; GO:0006915; GO:0007219; GO:0008270; GO:0016567; GO:0031410; GO:0043231; GO:0043410; GO:0070372; GO:2001235 496 XR_006398069.1 140 59 22 38 14 Q6Q0C0 5.62e-95 E3 ubiquitin-protein ligase TRAF7 (EC 2.3.2.27) (RING finger and WD repeat-containing protein 1) (RING finger protein 119) (RING-type E3 ubiquitin transferase TRAF7) (TNF receptor-associated factor 7) Homo sapiens (Human) apoptotic process [GO:0006915]; Notch signaling pathway [GO:0007219]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of MAPK cascade [GO:0043410]; protein ubiquitination [GO:0016567]; regulation of ERK1 and ERK2 cascade [GO:0070372]; ribosomal large subunit assembly [GO:0000027] GO:0000027; GO:0000151; GO:0004842; GO:0005730; GO:0005886; GO:0006915; GO:0007219; GO:0008270; GO:0016567; GO:0031410; GO:0043231; GO:0043410; GO:0070372; GO:2001235 497 XM_044323980.1 24 6 12 9 28 NA NA NA NA NA NA 498 XM_044327963.1 120 56 102 64 52 NA NA NA NA NA NA 499 XM_029338724.2 21 4 12 7 87 NA NA NA NA NA NA 500 XM_029325549.2 1219 1259 823 1093 1878 A7S7F2 0 Bystin Nematostella vectensis (Starlet sea anemone) rRNA processing [GO:0006364] GO:0005730; GO:0005737; GO:0006364; GO:0030515; GO:0030688 501 XR_006392564.1 2 55 7 45 65 NA NA NA NA NA NA 502 XR_006392182.1 50 18 34 79 25 NA NA NA NA NA NA 503 XM_029335452.2 330 4 144 6 3 NA NA NA NA NA NA 504 XM_044325839.1 0 0 0 0 9 NA NA NA NA NA NA 505 XM_029345764.2 1257 1430 302 710 735 O43592 0 Exportin-T (Exportin(tRNA)) (tRNA exportin) Homo sapiens (Human) intracellular protein transport [GO:0006886]; tRNA export from nucleus [GO:0006409]; tRNA re-export from nucleus [GO:0071528] GO:0000049; GO:0005643; GO:0005654; GO:0005737; GO:0005829; GO:0006409; GO:0006886; GO:0016363; GO:0031267; GO:0071528 506 XM_044311582.1 45 0 36 44 5 A7SGU6 2.01e-37 Proteasome assembly chaperone 2 Nematostella vectensis (Starlet sea anemone) proteasome assembly [GO:0043248] GO:0005634; GO:0005829; GO:0043248 507 XM_044311582.1 45 0 36 44 5 A7SGU6 2.01e-37 Proteasome assembly chaperone 2 Nematostella vectensis (Starlet sea anemone) proteasome assembly [GO:0043248] GO:0005634; GO:0005829; GO:0043248 508 XM_044308369.1 567 471 195 487 448 Q0E9H9 8.09e-22 NA NA NA NA 509 XM_029340207.2 2425 2295 1529 2105 1276 Q00535 2.97e-173 Cyclin-dependent kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) (Cyclin-dependent-like kinase 5) (Serine/threonine-protein kinase PSSALRE) (Tau protein kinase II catalytic subunit) (TPKII catalytic subunit) Homo sapiens (Human) axon extension [GO:0048675]; axonogenesis [GO:0007409]; behavioral response to cocaine [GO:0048148]; calcium ion import [GO:0070509]; cell division [GO:0051301]; cell-matrix adhesion [GO:0007160]; cellular response to amyloid-beta [GO:1904646]; central nervous system neuron development [GO:0021954]; cerebellar cortex formation [GO:0021697]; chemical synaptic transmission [GO:0007268]; corpus callosum development [GO:0022038]; cortical actin cytoskeleton organization [GO:0030866]; dendrite morphogenesis [GO:0048813]; excitatory postsynaptic potential [GO:0060079]; hippocampus development [GO:0021766]; intracellular protein transport [GO:0006886]; layer formation in cerebral cortex [GO:0021819]; microtubule cytoskeleton organization [GO:0000226]; mitochondrion organization [GO:0007005]; motor neuron axon guidance [GO:0008045]; negative regulation of axon extension [GO:0030517]; negative regulation of cell cycle [GO:0045786]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of neuron death [GO:1901215]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of proteolysis [GO:0045861]; negative regulation of synaptic plasticity [GO:0031914]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; nucleocytoplasmic transport [GO:0006913]; oligodendrocyte differentiation [GO:0048709]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; phosphorylation [GO:0016310]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of glial cell apoptotic process [GO:0034352]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of presynaptic cytosolic calcium concentration [GO:0099533]; positive regulation of protein binding [GO:0032092]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; protein autophosphorylation [GO:0046777]; protein localization to synapse [GO:0035418]; protein phosphorylation [GO:0006468]; receptor catabolic process [GO:0032801]; receptor clustering [GO:0043113]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell migration [GO:0030334]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of macroautophagy [GO:0016241]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of synapse pruning [GO:1905806]; regulation of synaptic plasticity [GO:0048167]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of synaptic vesicle recycling [GO:1903421]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to wounding [GO:0009611]; rhythmic process [GO:0048511]; Schwann cell development [GO:0014044]; sensory perception of pain [GO:0019233]; serine phosphorylation of STAT protein [GO:0042501]; skeletal muscle tissue development [GO:0007519]; synapse assembly [GO:0007416]; synaptic transmission, dopaminergic [GO:0001963]; synaptic transmission, glutamatergic [GO:0035249]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle exocytosis [GO:0016079]; synaptic vesicle transport [GO:0048489]; visual learning [GO:0008542] GO:0000083; GO:0000226; GO:0000307; GO:0001764; GO:0001963; GO:0002039; GO:0004672; GO:0004674; GO:0004693; GO:0005176; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005874; GO:0005886; GO:0006468; GO:0006886; GO:0006913; GO:0007005; GO:0007160; GO:0007268; GO:0007409; GO:0007416; GO:0007519; GO:0008045; GO:0008542; GO:0009611; GO:0014044; GO:0014069; GO:0016020; GO:0016079; GO:0016241; GO:0016301; GO:0016310; GO:0016533; GO:0018105; GO:0018107; GO:0019233; GO:0019901; GO:0021697; GO:0021766; GO:0021819; GO:0021954; GO:0022038; GO:0030027; GO:0030054; GO:0030175; GO:0030182; GO:0030334; GO:0030424; GO:0030425; GO:0030426; GO:0030517; GO:0030549; GO:0030866; GO:0031175; GO:0031397; GO:0031594; GO:0031914; GO:0032092; GO:0032801; GO:0034352; GO:0035173; GO:0035249; GO:0035418; GO:0042501; GO:0042981; GO:0043005; GO:0043025; GO:0043113; GO:0043125; GO:0043204; GO:0043525; GO:0045786; GO:0045860; GO:0045861; GO:0045892; GO:0045956; GO:0046777; GO:0046826; GO:0046875; GO:0048148; GO:0048156; GO:0048167; GO:0048488; GO:0048489; GO:0048511; GO:0048675; GO:0048709; GO:0048813; GO:0050321; GO:0051301; GO:0051402; GO:0051726; GO:0051879; GO:0051966; GO:0060079; GO:0061001; GO:0070509; GO:0090314; GO:0098685; GO:0098793; GO:0098978; GO:0099509; GO:0099533; GO:0106310; GO:1901215; GO:1901387; GO:1903076; GO:1903421; GO:1904646; GO:1905806; GO:2000251 510 XM_029347715.2 731 117 195 202 351 Q7YSW8 1.08e-52 Serine/threonine-protein phosphatase 2B catalytic subunit (EC 3.1.3.16) (Calcineurin subunit A) Dictyostelium discoideum (Social amoeba) calcineurin-mediated signaling [GO:0097720]; regulation of sorocarp development [GO:0031156]; response to cation stress [GO:0043157]; response to differentiation-inducing factor 1 [GO:1903013]; sorocarp spore cell differentiation [GO:0044671]; sorocarp stalk cell differentiation [GO:0031149] GO:0004722; GO:0005516; GO:0005737; GO:0005955; GO:0017018; GO:0031149; GO:0031156; GO:0033192; GO:0043157; GO:0044671; GO:0046872; GO:0097720; GO:1903013 511 XM_044314475.1 0 0 35 0 495 Q9NZJ4 0 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 512 XM_044314475.1 0 0 35 0 495 Q9NZJ4 4.87e-42 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 513 XM_029357177.2 83 62 135 181 68 NA NA NA NA NA NA 514 XR_006392235.1 156 160 35 159 154 NA NA NA NA NA NA 515 XM_029358432.2 89 192 28 60 16 NA NA NA NA NA NA 516 XM_029358190.2 280 85 136 147 361 NA NA NA NA NA NA 517 XM_029346070.2 1274 1047 584 598 579 F1RAX8 9.77e-168 Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial (EC 1.14.13.-) (Coenzyme Q10 monooxygenase 6) Danio rerio (Zebrafish) (Brachydanio rerio) ubiquinone biosynthetic process [GO:0006744] GO:0005739; GO:0005794; GO:0006744; GO:0008681; GO:0016491; GO:0016709; GO:0031314; GO:0042995; GO:0071949; GO:0106364 518 XM_029344628.2 0 0 0 77 149 NA NA NA NA NA NA 519 XM_044317991.1 244 74 253 173 273 P31580 1.54e-44 High choriolytic enzyme 1 (EC 3.4.24.67) (Choriolysin H 1) (HCE23) (Hatching enzyme zinc-protease subunit HCE 1) Oryzias latipes (Japanese rice fish) (Japanese killifish) proteolysis [GO:0006508] GO:0004222; GO:0006508; GO:0008270; GO:0042588 520 XM_029343467.2 49 0 0 56 42 NA NA NA NA NA NA 521 XM_029339996.2 271 247 132 224 403 Q9PTS2 7.58e-140 Uroporphyrinogen decarboxylase (UPD) (URO-D) (EC 4.1.1.37) Danio rerio (Zebrafish) (Brachydanio rerio) heme biosynthetic process [GO:0006783]; porphyrin-containing compound catabolic process [GO:0006787]; porphyrin-containing compound metabolic process [GO:0006778]; protoporphyrinogen IX biosynthetic process [GO:0006782] GO:0004853; GO:0005829; GO:0006778; GO:0006782; GO:0006783; GO:0006787 522 XM_044319002.1 490 74 400 140 364 Q9BXB4 0 Oxysterol-binding protein-related protein 11 (ORP-11) (OSBP-related protein 11) Homo sapiens (Human) fat cell differentiation [GO:0045444]; positive regulation of sequestering of triglyceride [GO:0010890] GO:0005654; GO:0005794; GO:0005829; GO:0010890; GO:0015248; GO:0016020; GO:0031902; GO:0032934; GO:0043231; GO:0045444 523 XM_044312192.1 19 13 74 6 116 NA NA NA NA NA NA 524 XM_029342756.2 4 0 9 23 11 P30974 9.3e-26 Tachykinin-like peptides receptor 86C (NKD) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; inter-male aggressive behavior [GO:0002121]; neuropeptide signaling pathway [GO:0007218]; tachykinin receptor signaling pathway [GO:0007217] GO:0002121; GO:0004995; GO:0005886; GO:0007186; GO:0007217; GO:0007218; GO:0008188; GO:0016020 525 XM_044313577.1 58 9 91 88 516 NA NA NA NA NA NA 526 XM_029350640.2 469 1062 304 1115 963 Q28005 3.49e-95 Lutropin-choriogonadotropic hormone receptor (LH/CG-R) (Luteinizing hormone receptor) (LSH-R) Bos taurus (Bovine) activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cellular response to luteinizing hormone stimulus [GO:0071373]; hormone-mediated signaling pathway [GO:0009755]; luteinizing hormone signaling pathway [GO:0042700]; male gonad development [GO:0008584]; ovarian follicle development [GO:0001541]; ovulation cycle process [GO:0022602]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200] GO:0001541; GO:0004964; GO:0005886; GO:0007189; GO:0007190; GO:0007200; GO:0008528; GO:0008584; GO:0009755; GO:0022602; GO:0042700; GO:0071373 527 XM_029343569.2 37 5 9 11 32 NA NA NA NA NA NA 528 XM_029349896.2 0 123 17 0 27 Q9UJJ9 9.37e-51 N-acetylglucosamine-1-phosphotransferase subunit gamma (GlcNAc-1-phosphotransferase subunit gamma) (UDP-N-acetylglucosamine-1-phosphotransferase subunit gamma) Homo sapiens (Human) carbohydrate phosphorylation [GO:0046835]; N-glycan processing to lysosome [GO:0016256] GO:0000139; GO:0003976; GO:0005794; GO:0016256; GO:0042803; GO:0046835; GO:0070062; GO:0070622 529 XR_003826448.2 4 1073 328 561 265 NA NA NA NA NA NA 530 XM_029347731.2 0 0 13 1 5 NA NA NA NA NA NA 531 XM_044319990.1 0 34 0 63 23 NA NA NA NA NA NA 532 XM_044315600.1 0 0 6 36 5 NA NA NA NA NA NA 533 XM_044318601.1 30 65 25 37 16 NA NA NA NA NA NA 534 XM_044309697.1 1153 665 677 764 839 NA NA NA NA NA NA 535 XM_029342385.2 68 22 0 19 62 NA NA NA NA NA NA 536 XM_044325174.1 25 75 29 125 83 NA NA NA NA NA NA 537 XM_044325822.1 9 4 18 27 27 NA NA NA NA NA NA 538 XM_044324264.1 0 14 0 19 8 P07949 3.27e-80 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; axon guidance [GO:0007411]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; lymphocyte migration into lymphoid organs [GO:0097021]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; posterior midgut development [GO:0007497]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006468; GO:0006919; GO:0007156; GO:0007158; GO:0007165; GO:0007169; GO:0007411; GO:0007497; GO:0009410; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0038023; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0097021; GO:0098797; GO:2001241 539 XM_044319735.1 39 33 15 0 0 NA NA NA NA NA NA 540 XM_044321132.1 5 0 6 12 0 Q9U6Y5 9.12e-146 GFP-like fluorescent chromoprotein FP506 (zFP506) Zoanthus sp. (Green polyp) bioluminescence [GO:0008218] GO:0008218 541 XM_029330380.2 421 172 125 197 258 Q5PQJ7 7.79e-90 Tubulin-specific chaperone cofactor E-like protein (Leucine-rich repeat-containing protein 35) Rattus norvegicus (Rat) microtubule cytoskeleton organization [GO:0000226]; post-chaperonin tubulin folding pathway [GO:0007023]; tubulin complex assembly [GO:0007021] GO:0000226; GO:0005737; GO:0005856; GO:0007021; GO:0007023; GO:0043014 542 XM_029334401.2 62 61 15 73 107 NA NA NA NA NA NA 543 XM_029330658.2 356 191 142 172 264 NA NA NA NA NA NA 544 XM_029355746.2 4775 4166 2689 4255 4094 G5EFS2 1.29e-40 NA NA NA NA 545 XR_006396636.1 20 5 24 8 29 NA NA NA NA NA NA 546 XM_044316821.1 335 213 185 350 300 NA NA NA NA NA NA 547 XM_029335672.1 3813 3823 2372 3330 3757 P48375 8.99e-46 Peptidyl-prolyl cis-trans isomerase Fkbp12 (PPIase Fkbp12) (EC 5.2.1.8) (12 kDa FK506-binding protein) (12 kDa FKBP) (Macrolide-binding protein) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Drosophila melanogaster (Fruit fly) chaperone-mediated protein folding [GO:0061077]; protein peptidyl-prolyl isomerization [GO:0000413] GO:0000413; GO:0003755; GO:0005737; GO:0005829; GO:0005886; GO:0034713; GO:0061077 548 XM_044327776.1 5 0 0 10 0 NA NA NA NA NA NA 549 XM_044310406.1 3 26 40 2 22 NA NA NA NA NA NA 550 XM_044311800.1 49 46 18 99 53 NA NA NA NA NA NA 551 XM_044324228.1 19 48 123 261 315 NA NA NA NA NA NA 552 XM_029331604.2 60 104 97 253 72 NA NA NA NA NA NA 553 XM_044312991.1 159 83 63 32 217 NA NA NA NA NA NA 554 XR_006396931.1 322 142 100 190 221 NA NA NA NA NA NA 555 XM_044327559.1 646 324 363 687 526 NA NA NA NA NA NA 556 XM_044325825.1 43 414 1 2 1 NA NA NA NA NA NA 557 XM_029350189.2 52 36 14 60 60 NA NA NA NA NA NA 558 XM_044309647.1 349 178 255 243 346 Q9Z2W0 0 Aspartyl aminopeptidase (EC 3.4.11.21) Mus musculus (Mouse) proteolysis [GO:0006508] GO:0004177; GO:0005829; GO:0006508; GO:0008237; GO:0008270; GO:0042802 559 XM_029333468.2 329 328 51 6 14 NA NA NA NA NA NA 560 XM_044315677.1 40 23 22 51 97 NA NA NA NA NA NA 561 XR_006395117.1 19 9 237 15 0 NA NA NA NA NA NA 562 XM_029339289.2 504 385 365 486 456 NA NA NA NA NA NA 563 XR_006397320.1 211 91 79 74 211 NA NA NA NA NA NA 564 XM_029327029.2 266 303 58 183 104 Q8TDB6 4.56e-27 E3 ubiquitin-protein ligase DTX3L (EC 2.3.2.27) (B-lymphoma- and BAL-associated protein) (Protein deltex-3-like) (RING-type E3 ubiquitin transferase DTX3L) (Rhysin-2) (Rhysin2) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; defense response to virus [GO:0051607]; DNA damage checkpoint signaling [GO:0000077]; double-strand break repair [GO:0006302]; endosome to lysosome transport [GO:0008333]; histone H2A ubiquitination [GO:0033522]; histone H2B ubiquitination [GO:0033523]; histone monoubiquitination [GO:0010390]; innate immune response [GO:0045087]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; Notch signaling pathway [GO:0007219]; positive regulation of chromatin binding [GO:0035563]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of receptor catabolic process [GO:2000646]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein transport [GO:0015031]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000077; GO:0002230; GO:0004842; GO:0004857; GO:0005634; GO:0005654; GO:0005737; GO:0005764; GO:0005765; GO:0005829; GO:0006302; GO:0006325; GO:0006511; GO:0006974; GO:0007219; GO:0008333; GO:0010390; GO:0015031; GO:0016567; GO:0019899; GO:0031901; GO:0032092; GO:0032991; GO:0033522; GO:0033523; GO:0035563; GO:0042393; GO:0044389; GO:0045087; GO:0045893; GO:0046872; GO:0051444; GO:0051607; GO:0051865; GO:0061630; GO:0070936; GO:0097677; GO:0140768; GO:1900182; GO:1902966; GO:2000646 565 XR_003824613.2 6 20 7 7 27 NA NA NA NA NA NA 566 XM_029338864.2 10273 13979 8373 15354 12574 A6NIH7 2.01e-88 Protein unc-119 homolog B Homo sapiens (Human) cilium assembly [GO:0060271]; lipoprotein transport [GO:0042953]; nervous system development [GO:0007399] GO:0005829; GO:0005929; GO:0007399; GO:0008289; GO:0035869; GO:0042953; GO:0060271 567 XM_044325258.1 1 0 3 4 34 NA NA NA NA NA NA 568 XM_044308534.1 0 0 12 0 0 NA NA NA NA NA NA 569 XM_044327056.1 528 866 681 2786 1736 NA NA NA NA NA NA 570 XM_029350008.2 13 0 9 1 30 Q8I7P9 1.86e-50 Retrovirus-related Pol polyprotein from transposon opus [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508]; transposition, DNA-mediated [GO:0006313] GO:0003676; GO:0003887; GO:0003964; GO:0004519; GO:0005634; GO:0006313; GO:0006508; GO:0008233; GO:0015074; GO:0042575 571 XM_029350008.2 13 0 9 1 30 Q8I7P9 1.86e-50 Retrovirus-related Pol polyprotein from transposon opus [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508]; transposition, DNA-mediated [GO:0006313] GO:0003676; GO:0003887; GO:0003964; GO:0004519; GO:0005634; GO:0006313; GO:0006508; GO:0008233; GO:0015074; GO:0042575 572 XM_044321277.1 399 196 194 213 168 O93602 1.88e-36 Cyclic AMP-dependent transcription factor ATF-2 (cAMP-dependent transcription factor ATF-2) (Activating transcription factor 2) Gallus gallus (Chicken) cellular response to DNA damage stimulus [GO:0006974]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005741; GO:0006357; GO:0006974; GO:0035497; GO:0046872 573 XM_044321277.1 399 196 194 213 168 O93602 8.1e-32 Cyclic AMP-dependent transcription factor ATF-2 (cAMP-dependent transcription factor ATF-2) (Activating transcription factor 2) Gallus gallus (Chicken) cellular response to DNA damage stimulus [GO:0006974]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005741; GO:0006357; GO:0006974; GO:0035497; GO:0046872 574 XM_044327063.1 0 62 187 0 0 B2GUB3 6.09e-178 Tubulin tyrosine ligase 3 (EC 6.3.2.-) (Tubulin--tyrosine ligase protein 3) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) protein polyglycylation [GO:0018094] GO:0005524; GO:0005737; GO:0005874; GO:0018094; GO:0031514; GO:0046872; GO:0070736 575 XM_044310761.1 0 0 7 14 17 NA NA NA NA NA NA 576 XM_044307743.1 0 0 11 0 25 P0DP43 1.79e-39 Cation channel sperm-associated auxiliary subunit epsilon (CatSper-epsilon) (CatSperepsilon) (C1orf101-like protein) Mus musculus (Mouse) flagellated sperm motility [GO:0030317]; sperm capacitation [GO:0048240] GO:0030317; GO:0036128; GO:0048240; GO:0097228 577 XM_044314786.1 13 5 4 19 24 NA NA NA NA NA NA 578 XM_044324985.1 0 5 1 0 26 NA NA NA NA NA NA 579 XM_044325958.1 20 3 0 0 16 P36241 1.16e-76 60S ribosomal protein L19 Drosophila melanogaster (Fruit fly) cytoplasmic translation [GO:0002181] GO:0002181; GO:0003723; GO:0003735; GO:0022625; GO:0022626 580 XM_044317765.1 309 154 303 253 592 Q4FAT7 6.13e-43 Beta-glucuronidase (EC 3.2.1.31) Sus scrofa (Pig) chondroitin sulfate catabolic process [GO:0030207]; glucuronoside catabolic process [GO:0019391]; heparan sulfate proteoglycan catabolic process [GO:0030200]; hyaluronan catabolic process [GO:0030214] GO:0004566; GO:0005102; GO:0005615; GO:0019391; GO:0019904; GO:0030200; GO:0030207; GO:0030214; GO:0030246; GO:0043202 581 XM_029334874.2 736 473 409 618 773 NA NA NA NA NA NA 582 XM_029325495.2 76 8 44 17 33 NA NA NA NA NA NA 583 XR_003824298.2 30 7 0 0 87 NA NA NA NA NA NA 584 XM_044309757.1 32 12 87 103 109 O75581 0 Low-density lipoprotein receptor-related protein 6 (LRP-6) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; chemical synaptic transmission [GO:0007268]; dopaminergic neuron differentiation [GO:0071542]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001933; GO:0005041; GO:0005102; GO:0005109; GO:0005576; GO:0005783; GO:0005886; GO:0006469; GO:0007204; GO:0007268; GO:0009986; GO:0014029; GO:0014033; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0031410; GO:0031901; GO:0034392; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043434; GO:0044335; GO:0044340; GO:0045121; GO:0045202; GO:0045787; GO:0045893; GO:0045944; GO:0051091; GO:0060070; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072659; GO:0090118; GO:0090244; GO:0098609; GO:1904928; GO:1904948; GO:1904953; GO:1990851; GO:1990909 585 XM_044309757.1 32 12 87 103 109 O75581 3.99e-167 Low-density lipoprotein receptor-related protein 6 (LRP-6) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; chemical synaptic transmission [GO:0007268]; dopaminergic neuron differentiation [GO:0071542]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001933; GO:0005041; GO:0005102; GO:0005109; GO:0005576; GO:0005783; GO:0005886; GO:0006469; GO:0007204; GO:0007268; GO:0009986; GO:0014029; GO:0014033; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0031410; GO:0031901; GO:0034392; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043434; GO:0044335; GO:0044340; GO:0045121; GO:0045202; GO:0045787; GO:0045893; GO:0045944; GO:0051091; GO:0060070; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072659; GO:0090118; GO:0090244; GO:0098609; GO:1904928; GO:1904948; GO:1904953; GO:1990851; GO:1990909 586 XM_044309757.1 32 12 87 103 109 O75581 1.43e-89 Low-density lipoprotein receptor-related protein 6 (LRP-6) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; chemical synaptic transmission [GO:0007268]; dopaminergic neuron differentiation [GO:0071542]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001933; GO:0005041; GO:0005102; GO:0005109; GO:0005576; GO:0005783; GO:0005886; GO:0006469; GO:0007204; GO:0007268; GO:0009986; GO:0014029; GO:0014033; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0031410; GO:0031901; GO:0034392; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043434; GO:0044335; GO:0044340; GO:0045121; GO:0045202; GO:0045787; GO:0045893; GO:0045944; GO:0051091; GO:0060070; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072659; GO:0090118; GO:0090244; GO:0098609; GO:1904928; GO:1904948; GO:1904953; GO:1990851; GO:1990909 587 XM_044325166.1 11 2 58 31 159 NA NA NA NA NA NA 588 XM_044319676.1 766 279 285 615 306 NA NA NA NA NA NA 589 XM_044317090.1 3 0 18 2 6 Q9N126 1.2e-62 Retinol dehydrogenase 8 (EC 1.1.1.300) (Photoreceptor outer segment all-trans retinol dehydrogenase) Bos taurus (Bovine) estrogen biosynthetic process [GO:0006703]; response to stimulus [GO:0050896]; retinol metabolic process [GO:0042572]; visual perception [GO:0007601] GO:0004303; GO:0004745; GO:0005829; GO:0006703; GO:0007601; GO:0016491; GO:0042572; GO:0042622; GO:0050896; GO:0052650 590 XM_029344614.2 155 30 314 327 330 Q9NZN8 7.01e-124 CCR4-NOT transcription complex subunit 2 (CCR4-associated factor 2) Homo sapiens (Human) negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; positive regulation of cytoplasmic mRNA processing body assembly [GO:0010606]; regulation of stem cell population maintenance [GO:2000036]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; RNA-mediated gene silencing [GO:0031047]; trophectodermal cell differentiation [GO:0001829] GO:0000122; GO:0000289; GO:0000932; GO:0001222; GO:0001829; GO:0003712; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0006357; GO:0010606; GO:0016020; GO:0030014; GO:0030015; GO:0031047; GO:0033147; GO:0090503; GO:2000036 591 XM_029346093.2 1637 425 0 1288 1560 A8WJ42 2.47e-21 COA8 family protein CBG23705, mitochondrial (COA8) (APOPT family protein CBG23705, mitochondrial) Caenorhabditis briggsae intrinsic apoptotic signaling pathway [GO:0097193] GO:0005739; GO:0005743; GO:0097193 592 XM_029323470.2 901 487 554 810 891 Q68CP4 3.61e-118 Heparan-alpha-glucosaminide N-acetyltransferase (EC 2.3.1.78) (Transmembrane protein 76) Homo sapiens (Human) heparan sulfate proteoglycan catabolic process [GO:0030200]; lysosomal transport [GO:0007041]; protein complex oligomerization [GO:0051259] GO:0005765; GO:0005886; GO:0007041; GO:0015019; GO:0016746; GO:0030200; GO:0035579; GO:0043202; GO:0051259; GO:0070821 593 XM_029351258.2 29 0 9 4 51 P18264 3.23e-28 Homeobox protein rough Drosophila virilis (Fruit fly) establishment of ommatidial planar polarity [GO:0042067]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R2/R5 cell fate commitment [GO:0007463]; response to stimulus [GO:0050896]; visual perception [GO:0007601] GO:0000977; GO:0000981; GO:0005634; GO:0007463; GO:0007601; GO:0042067; GO:0045944; GO:0050896 594 XM_044326931.1 823 382 482 319 400 R1CW23 2.72e-101 Dimethylsulfonioproprionate lyase 7 (DMSP lyase 7) (EC 4.4.1.3) (Dimethylpropiothetin dethiomethylase 7) Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi) NA GO:0047869 595 XM_029351002.2 154 158 173 106 123 NA NA NA NA NA NA 596 XM_044324996.1 0 14 15 21 14 Q80XJ3 2.27e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 597 XM_044324996.1 0 14 15 21 14 Q80XJ3 3.56e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 598 XM_044324996.1 0 14 15 21 14 Q80XJ3 2.04e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 599 XM_044324996.1 0 14 15 21 14 Q80XJ3 1.14e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 600 XM_044324996.1 0 14 15 21 14 Q80XJ3 1.48e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 601 XM_044324996.1 0 14 15 21 14 Q80XJ3 1.18e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 602 XM_044324996.1 0 14 15 21 14 Q80XJ3 6.18e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 603 XM_044324996.1 0 14 15 21 14 Q80XJ3 4.9e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 604 XR_003827814.2 11 12 8 17 25 NA NA NA NA NA NA 605 XM_044321031.1 38 5 48 29 27 NA NA NA NA NA NA 606 XM_029352302.2 3614 4303 2486 2680 1751 Q6P5M2 2.82e-166 SKI8 subunit of superkiller complex protein (WD repeat-containing protein 61) Danio rerio (Zebrafish) (Brachydanio rerio) histone H3-K4 methylation [GO:0051568]; transcription elongation by RNA polymerase II promoter [GO:0006368] GO:0000791; GO:0005634; GO:0005737; GO:0006368; GO:0016593; GO:0051568; GO:0055087 607 XM_029335317.2 945 173 187 1092 0 Q3US41 5.9e-133 Epithelial splicing regulatory protein 1 (RNA-binding motif protein 35A) (RNA-binding protein 35A) Mus musculus (Mouse) alternative mRNA splicing, via spliceosome [GO:0000380]; branching involved in salivary gland morphogenesis [GO:0060445]; epithelial cell proliferation [GO:0050673]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; positive regulation of epithelial cell proliferation [GO:0050679]; regulation of inner ear auditory receptor cell fate specification [GO:0042669]; regulation of RNA splicing [GO:0043484] GO:0000380; GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0016604; GO:0042669; GO:0043484; GO:0050673; GO:0050679; GO:0060441; GO:0060445; GO:1990904 608 XM_044325598.1 0 0 4 22 0 NA NA NA NA NA NA 609 XM_044312427.1 2365 3007 2433 15 1500 NA NA NA NA NA NA 610 XR_006392362.1 88 33 34 40 55 NA NA NA NA NA NA 611 XM_044312791.1 9 13 1 97 23 NA NA NA NA NA NA 612 XM_044329223.1 4 0 7 0 25 NA NA NA NA NA NA 613 XM_029349470.2 1336 949 713 1416 1367 O94988 4.64e-43 Protein FAM13A Homo sapiens (Human) regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] GO:0005096; GO:0005829; GO:0007165; GO:0051056 614 XM_029349470.2 1336 949 713 1416 1367 O94988 1.93e-29 Protein FAM13A Homo sapiens (Human) regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] GO:0005096; GO:0005829; GO:0007165; GO:0051056 615 XM_029350666.2 775 43 0 355 787 Q99759 1.26e-43 Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3) Homo sapiens (Human) blood vessel development [GO:0001568]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; negative regulation of cellular senescence [GO:2000773]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell proliferation in bone marrow [GO:0071864]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of p38MAPK cascade [GO:1900745]; protein autophosphorylation [GO:0046777] GO:0000165; GO:0001568; GO:0004672; GO:0004674; GO:0004709; GO:0005524; GO:0005737; GO:0005829; GO:0035556; GO:0043123; GO:0046777; GO:0046872; GO:0071864; GO:0090050; GO:0106310; GO:1900745; GO:2000773 616 XM_044312075.1 0 0 0 8 0 NA NA NA NA NA NA 617 XM_029355289.2 0 0 0 4 19 A0A1B0GUU1 6.09e-39 Uncharacterized protein C17orf113 Homo sapiens (Human) NA NA 618 XM_029349363.2 479 318 269 430 482 Q8CHB8 0 Tubulin polyglutamylase TTLL5 (EC 6.3.2.-) (Tubulin--tyrosine ligase-like protein 5) Mus musculus (Mouse) fertilization [GO:0009566]; flagellated sperm motility [GO:0030317]; microtubule cytoskeleton organization [GO:0000226]; protein polyglutamylation [GO:0018095]; retina development in camera-type eye [GO:0060041]; sperm axoneme assembly [GO:0007288]; spermatogenesis [GO:0007283] GO:0000226; GO:0005524; GO:0005634; GO:0005813; GO:0005829; GO:0005874; GO:0005886; GO:0005929; GO:0007283; GO:0007288; GO:0009566; GO:0015631; GO:0018095; GO:0030317; GO:0036064; GO:0046872; GO:0060041; GO:0070740; GO:0097731 619 XM_044314939.1 0 20 5 0 4 NA NA NA NA NA NA 620 XM_044310584.1 0 0 0 10 0 NA NA NA NA NA NA 621 XM_029348289.2 111 0 103 224 359 Q91WI7 3.82e-33 KICSTOR complex protein ITFG2 (Integrin-alpha FG-GAP repeat-containing protein 2) Mus musculus (Mouse) cellular response to amino acid starvation [GO:0034198]; cellular response to glucose starvation [GO:0042149]; germinal center B cell differentiation [GO:0002314]; negative regulation of TORC1 signaling [GO:1904262]; regulation of TOR signaling [GO:0032006] GO:0002314; GO:0005654; GO:0005765; GO:0005829; GO:0032006; GO:0034198; GO:0042149; GO:0140007; GO:1904262 622 XM_029348289.2 111 0 103 224 359 Q91WI7 2.74e-30 KICSTOR complex protein ITFG2 (Integrin-alpha FG-GAP repeat-containing protein 2) Mus musculus (Mouse) cellular response to amino acid starvation [GO:0034198]; cellular response to glucose starvation [GO:0042149]; germinal center B cell differentiation [GO:0002314]; negative regulation of TORC1 signaling [GO:1904262]; regulation of TOR signaling [GO:0032006] GO:0002314; GO:0005654; GO:0005765; GO:0005829; GO:0032006; GO:0034198; GO:0042149; GO:0140007; GO:1904262 623 XM_044312989.1 138 159 184 168 188 Q5ZKD5 0 RRP12-like protein Gallus gallus (Chicken) rRNA processing [GO:0006364] GO:0005730; GO:0006364; GO:0031965 624 XM_044319106.1 616 212 409 532 580 NA NA NA NA NA NA 625 XM_044314239.1 25 132 77 21 87 Q96AY4 8.1e-159 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 626 XM_044314239.1 25 132 77 21 87 Q96AY4 6.43e-157 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 627 XM_044314239.1 25 132 77 21 87 Q96AY4 7.03e-137 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 628 XM_029337049.2 10 0 0 44 0 NA NA NA NA NA NA 629 XR_003824995.2 80 0 43 16 140 NA NA NA NA NA NA 630 XM_044323544.1 10 0 0 0 11 Q63357 0 Unconventional myosin-Id (Myosin heavy chain myr 4) Rattus norvegicus (Rat) actin filament organization [GO:0007015]; cellular localization [GO:0051641]; forebrain development [GO:0030900]; protein transport [GO:0015031]; vesicle transport along actin filament [GO:0030050] GO:0000146; GO:0005516; GO:0005524; GO:0005737; GO:0005769; GO:0005790; GO:0005886; GO:0005902; GO:0005903; GO:0005938; GO:0007015; GO:0015031; GO:0015629; GO:0016323; GO:0016459; GO:0019904; GO:0030050; GO:0030424; GO:0030673; GO:0030900; GO:0031410; GO:0031982; GO:0043005; GO:0043025; GO:0043204; GO:0043209; GO:0044853; GO:0048306; GO:0051015; GO:0051641; GO:0097440 631 XR_003827487.2 65 183 70 23 45 NA NA NA NA NA NA 632 XR_006396951.1 12 1 8 4 29 NA NA NA NA NA NA 633 XM_029348161.2 4148 4306 3471 4734 4494 Q2LC84 3.76e-49 Protein numb homolog Rattus norvegicus (Rat) adherens junction organization [GO:0034332]; axonogenesis [GO:0007409]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; forebrain development [GO:0030900]; lateral ventricle development [GO:0021670]; lung epithelial cell differentiation [GO:0060487]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein localization to plasma membrane [GO:1903077]; nervous system development [GO:0007399]; neuroblast division in subventricular zone [GO:0021849]; neuroblast proliferation [GO:0007405]; positive regulation of cell migration [GO:0030335]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of neurogenesis [GO:0050769]; positive regulation of polarized epithelial cell differentiation [GO:0030862]; regulation of neuron differentiation [GO:0045664]; regulation of postsynapse assembly [GO:0150052]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149] GO:0005543; GO:0005634; GO:0005737; GO:0005769; GO:0005886; GO:0005905; GO:0007399; GO:0007405; GO:0007409; GO:0008013; GO:0008283; GO:0010008; GO:0014069; GO:0016323; GO:0019897; GO:0021670; GO:0021849; GO:0030136; GO:0030154; GO:0030335; GO:0030862; GO:0030900; GO:0031410; GO:0034332; GO:0043197; GO:0045177; GO:0045294; GO:0045296; GO:0045664; GO:0045746; GO:0050769; GO:0050775; GO:0060487; GO:0098978; GO:0099149; GO:0150052; GO:1903077 634 XM_029345375.2 171 262 179 89 79 NA NA NA NA NA NA 635 XM_029357031.2 357 244 132 383 225 NA NA NA NA NA NA 636 XR_006395228.1 20 200 110 117 63 NA NA NA NA NA NA 637 XR_003822947.2 11 2 10 13 9 NA NA NA NA NA NA 638 XR_006395843.1 60 33 8 7 9 NA NA NA NA NA NA 639 XM_029349461.2 1784 1598 1055 1541 1247 NA NA NA NA NA NA 640 XR_006397094.1 8 8 0 4 4 NA NA NA NA NA NA 641 XM_044315553.1 0 0 0 0 18 NA NA NA NA NA NA 642 XM_029355086.2 63 9 20 102 0 NA NA NA NA NA NA 643 XM_029354190.2 17827 22517 8742 17090 13773 P21531 0 60S ribosomal protein L3 (L4) Rattus norvegicus (Rat) cellular response to interleukin-4 [GO:0071353]; translation [GO:0006412] GO:0003723; GO:0003735; GO:0005730; GO:0005840; GO:0006412; GO:0008097; GO:0022625; GO:0022626; GO:0032991; GO:0045202; GO:0071353 644 XR_006397598.1 2 0 0 0 10 NA NA NA NA NA NA 645 XM_044319127.1 0 0 7 10 0 NA NA NA NA NA NA 646 XM_029350837.2 528 464 160 314 308 Q5M845 1.31e-56 UPF0462 protein C4orf33 homolog Rattus norvegicus (Rat) NA NA 647 XM_029335576.2 0 0 0 0 96 Q7ZV34 1.56e-72 Malignant T-cell-amplified sequence 1 (MCT-1) Danio rerio (Zebrafish) (Brachydanio rerio) cell cycle [GO:0007049]; formation of translation preinitiation complex [GO:0001731] GO:0001731; GO:0003723; GO:0005737; GO:0007049 648 XR_003824480.2 75 211 68 296 249 NA NA NA NA NA NA 649 XR_006394880.1 0 0 10 0 2 NA NA NA NA NA NA 650 XM_029338291.2 218 61 125 220 134 Q95M17 1.75e-112 Acidic mammalian chitinase (AMCase) (EC 3.2.1.14) (Chitin-binding protein b04) (CBPb04) Bos taurus (Bovine) apoptotic process [GO:0006915]; chitin catabolic process [GO:0006032]; immune system process [GO:0002376]; polysaccharide catabolic process [GO:0000272]; positive regulation of chemokine production [GO:0032722]; production of molecular mediator involved in inflammatory response [GO:0002532] GO:0000272; GO:0002376; GO:0002532; GO:0004568; GO:0005615; GO:0005737; GO:0006032; GO:0006915; GO:0008061; GO:0032722 651 XM_029354479.2 122 137 218 92 462 Q9Y2X3 0 Nucleolar protein 58 (Nucleolar protein 5) Homo sapiens (Human) rRNA processing [GO:0006364]; snoRNA localization [GO:0048254] GO:0001094; GO:0001650; GO:0003723; GO:0005654; GO:0005730; GO:0005732; GO:0005829; GO:0006364; GO:0015030; GO:0016020; GO:0030515; GO:0031428; GO:0032040; GO:0048254; GO:0051117; GO:0070761 652 XM_044326486.1 220 137 153 117 196 Q5XIX3 4.13e-77 Protein artemis (EC 3.1.-.-) (DNA cross-link repair 1C protein) (SNM1-like protein) Rattus norvegicus (Rat) adaptive immune response [GO:0002250]; B cell differentiation [GO:0030183]; chromosome organization [GO:0051276]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; double-strand break repair via nonhomologous end joining [GO:0006303]; interstrand cross-link repair [GO:0036297]; protection from non-homologous end joining at telomere [GO:0031848]; response to ionizing radiation [GO:0010212]; telomere maintenance [GO:0000723]; V(D)J recombination [GO:0033151] GO:0000014; GO:0000723; GO:0002250; GO:0003684; GO:0005654; GO:0005794; GO:0006302; GO:0006303; GO:0006310; GO:0008409; GO:0010212; GO:0030183; GO:0031848; GO:0033151; GO:0035312; GO:0036297; GO:0051276; GO:0070419 653 XM_044317357.1 0 11 5 13 0 NA NA NA NA NA NA 654 XM_029335774.2 1 1 0 14 4 NA NA NA NA NA NA 655 XM_029347365.2 36 16 4 31 12 NA NA NA NA NA NA 656 XM_044322375.1 11 0 13 0 59 NA NA NA NA NA NA 657 XM_044317004.1 555 440 118 287 203 P97329 3.39e-122 Kinesin-like protein KIF20A (Kinesin-like protein 174) (Rab6-interacting kinesin-like protein) (Rabkinesin-6) Mus musculus (Mouse) microtubule bundle formation [GO:0001578]; microtubule-based movement [GO:0007018]; midbody abscission [GO:0061952]; mitotic cytokinesis [GO:0000281]; protein transport [GO:0015031]; regulation of cytokinesis [GO:0032465] GO:0000281; GO:0001578; GO:0003777; GO:0005524; GO:0005634; GO:0005654; GO:0005794; GO:0005819; GO:0005871; GO:0005874; GO:0007018; GO:0008017; GO:0015031; GO:0016887; GO:0019901; GO:0030496; GO:0032465; GO:0045171; GO:0061952 658 XM_044322312.1 24 3 7 6 4 Q07497 2.55e-29 Ephrin type-B receptor 5 (EC 2.7.10.1) (EPH-like kinase 9) (EK9) (cEK9) Gallus gallus (Chicken) axon guidance [GO:0007411]; central nervous system projection neuron axonogenesis [GO:0021952]; positive regulation of kinase activity [GO:0033674]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0004714; GO:0005005; GO:0005524; GO:0005886; GO:0007169; GO:0007411; GO:0021952; GO:0033674; GO:0043005; GO:0043235 659 XR_006397254.1 69 16 11 8 17 NA NA NA NA NA NA 660 XM_029336324.2 20 41 0 116 0 NA NA NA NA NA NA 661 XM_044310061.1 0 0 8 0 5 NA NA NA NA NA NA 662 XM_044309736.1 0 0 0 6 1 NA NA NA NA NA NA 663 XM_044314569.1 5 29 0 11 0 NA NA NA NA NA NA 664 XM_044318692.1 591 0 0 245 0 Q6GN08 0 NA NA NA NA 665 XM_044308714.1 15 30 56 28 56 NA NA NA NA NA NA 666 XM_029342171.2 869 625 344 886 643 NA NA NA NA NA NA 667 XM_044321627.1 1 164 0 0 0 P49914 7.95e-68 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) (5,10-methenyl-tetrahydrofolate synthetase) (MTHFS) (Methenyl-THF synthetase) Homo sapiens (Human) folic acid catabolic process [GO:0046657]; folic acid metabolic process [GO:0046655]; folic acid-containing compound biosynthetic process [GO:0009396]; formate metabolic process [GO:0015942]; glutamate metabolic process [GO:0006536]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653] GO:0005524; GO:0005542; GO:0005737; GO:0005739; GO:0005759; GO:0005829; GO:0006536; GO:0009396; GO:0015942; GO:0030272; GO:0035999; GO:0046653; GO:0046655; GO:0046657; GO:0046872 668 XM_029330552.2 10 1 0 0 2 NA NA NA NA NA NA 669 XR_003824773.2 327 2368 1171 1081 540 NA NA NA NA NA NA 670 XM_044311744.1 0 3 0 6 0 Q1WK23 6.12e-22 Serine protease 23 (EC 3.4.21.-) Macaca mulatta (Rhesus macaque) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 671 XM_029355630.2 472 360 338 509 79 Q9NVD3 4.44e-54 SET domain-containing protein 4 (EC 2.1.1.-) (EC 2.1.1.364) Homo sapiens (Human) histone H3-K4 dimethylation [GO:0044648]; histone H3-K4 monomethylation [GO:0097692]; inflammatory response [GO:0006954]; peptidyl-lysine monomethylation [GO:0018026]; peptidyl-lysine trimethylation [GO:0018023]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell proliferation in bone marrow [GO:0071863] GO:0005634; GO:0005829; GO:0006954; GO:0016279; GO:0018023; GO:0018026; GO:0032755; GO:0032760; GO:0042799; GO:0042800; GO:0044648; GO:0050729; GO:0071863; GO:0097692; GO:0140941; GO:0140944; GO:0140945 672 XM_044324359.1 0 62 0 0 389 NA NA NA NA NA NA 673 XM_044325831.1 3 8 47 11 51 NA NA NA NA NA NA 674 XR_006391637.1 118 114 414 576 168 Q6INU7 1.1e-25 Putative ferric-chelate reductase 1 (EC 1.-.-.-) Xenopus laevis (African clawed frog) NA GO:0016020; GO:0016491; GO:0046872 675 XM_044319204.1 7 0 0 0 5 NA NA NA NA NA NA 676 XM_044317138.1 140 182 76 458 388 NA NA NA NA NA NA 677 XM_044314171.1 166 103 97 71 111 P51955 6.27e-140 Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis A-related kinase 2) (NimA-related protein kinase 2) (NimA-like protein kinase 1) Homo sapiens (Human) blastocyst development [GO:0001824]; cell division [GO:0051301]; centrosome separation [GO:0051299]; chromosome segregation [GO:0007059]; meiotic cell cycle [GO:0051321]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly [GO:0090307]; negative regulation of centriole-centriole cohesion [GO:1903126]; negative regulation of DNA binding [GO:0043392]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of mitotic centrosome separation [GO:0046602]; regulation of mitotic nuclear division [GO:0007088]; spindle assembly [GO:0051225] GO:0000070; GO:0000278; GO:0000776; GO:0000794; GO:0000922; GO:0001824; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005813; GO:0005829; GO:0005874; GO:0006468; GO:0007059; GO:0007088; GO:0019903; GO:0030496; GO:0032212; GO:0032991; GO:0043392; GO:0046602; GO:0046777; GO:0046872; GO:0051225; GO:0051299; GO:0051301; GO:0051321; GO:0051973; GO:0051988; GO:0090307; GO:0106310; GO:1903126; GO:1904355 678 XM_044318311.1 149 17 18 41 35 Q9SZJ2 1.15e-37 Glycine-rich domain-containing protein 2 (AtGRDP2) Arabidopsis thaliana (Mouse-ear cress) auxin-activated signaling pathway [GO:0009734]; cellular response to osmotic stress [GO:0071470]; regulation of auxin mediated signaling pathway [GO:0010928]; regulation of photoperiodism, flowering [GO:2000028] GO:0009734; GO:0010928; GO:0071470; GO:2000028 679 XM_044317846.1 0 0 77 228 0 Q8BIY1 7.82e-82 G patch domain-containing protein 3 Mus musculus (Mouse) negative regulation of RIG-I signaling pathway [GO:0039536]; negative regulation of type I interferon production [GO:0032480]; positive regulation of DNA-templated transcription [GO:0045893] GO:0003676; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0032480; GO:0039536; GO:0045893 680 XM_044306925.1 24 0 6 44 0 NA NA NA NA NA NA 681 XM_029331518.2 998 1398 973 416 679 NA NA NA NA NA NA 682 XM_029329843.2 1457 1348 1795 1494 848 Q9Y376 2.51e-153 Calcium-binding protein 39 (MO25alpha) (Protein Mo25) Homo sapiens (Human) activation of protein kinase activity [GO:0032147]; cellular hypotonic response [GO:0071476]; intracellular signal transduction [GO:0035556]; negative regulation of potassium ion transmembrane transport [GO:1901380]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; response to activity [GO:0014823]; response to thyroid hormone [GO:0097066]; signal transduction [GO:0007165] GO:0005576; GO:0005737; GO:0005829; GO:0007165; GO:0010800; GO:0014823; GO:0016020; GO:0018105; GO:0019900; GO:0030018; GO:0030295; GO:0032147; GO:0034774; GO:0035556; GO:0043539; GO:0070062; GO:0071476; GO:0071902; GO:0097066; GO:1901017; GO:1901380; GO:1902554; GO:1904813 683 XR_006394560.1 6 0 45 21 15 NA NA NA NA NA NA 684 XM_044329058.1 494 360 158 313 278 NA NA NA NA NA NA 685 XR_006396998.1 188 39 8 0 94 NA NA NA NA NA NA 686 XM_044328729.1 36 57 0 160 123 NA NA NA NA NA NA 687 XM_044323410.1 0 0 14 0 10 NA NA NA NA NA NA 688 XM_029344652.2 129 60 69 114 87 Q96S44 2.48e-90 EKC/KEOPS complex subunit TP53RK (EC 3.6.-.-) (Atypical serine/threonine protein kinase TP53RK) (Nori-2) (TP53-regulating kinase) (EC 2.7.11.1) (p53-related protein kinase) Homo sapiens (Human) protein phosphorylation [GO:0006468]; regulation of signal transduction by p53 class mediator [GO:1901796]; tRNA processing [GO:0008033]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525] GO:0000408; GO:0002039; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006468; GO:0008033; GO:0016787; GO:0070525; GO:0106310; GO:1901796 689 XM_029346361.2 946 1297 508 1064 730 Q7T2D4 4.45e-114 Endoplasmic reticulum-Golgi intermediate compartment protein 2 Danio rerio (Zebrafish) (Brachydanio rerio) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] GO:0005783; GO:0005789; GO:0005794; GO:0006888; GO:0006890; GO:0016020; GO:0030134; GO:0033116 690 XM_029339169.2 0 191 32 0 233 Q5VTY9 3.65e-53 Protein-cysteine N-palmitoyltransferase HHAT (EC 2.3.1.-) (Hedgehog acyltransferase) (Melanoma antigen recognized by T-cells 2) (MART-2) (Skinny hedgehog protein 1) Homo sapiens (Human) N-terminal peptidyl-L-cysteine N-palmitoylation [GO:0018009]; protein palmitoylation [GO:0018345]; smoothened signaling pathway [GO:0007224] GO:0000139; GO:0005525; GO:0005783; GO:0005789; GO:0005794; GO:0007224; GO:0008374; GO:0016409; GO:0016746; GO:0018009; GO:0018345 691 XM_044313460.1 22 4 7 7 18 NA NA NA NA NA NA 692 XM_029350824.2 640 294 658 510 360 Q5MPA9 7.18e-174 Serine/threonine-protein kinase DCLK2 (EC 2.7.11.1) (CaMK-like CREB regulatory kinase 2) (CL2) (CLICK-II) (CLICK2) (Doublecortin-like and CAM kinase-like 2) (Doublecortin-like kinase 2) Rattus norvegicus (Rat) hippocampus development [GO:0021766]; intracellular signal transduction [GO:0035556]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of protein localization to nucleus [GO:1900181]; peptidyl-serine phosphorylation [GO:0018105]; protein localization to nucleus [GO:0034504]; pyramidal neuron development [GO:0021860] GO:0000226; GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0005856; GO:0008017; GO:0018105; GO:0021766; GO:0021860; GO:0034504; GO:0035556; GO:0106310; GO:1900181 693 XM_029357572.2 303 39 112 0 315 O95639 4.69e-116 Cleavage and polyadenylation specificity factor subunit 4 (Cleavage and polyadenylation specificity factor 30 kDa subunit) (CPSF 30 kDa subunit) (NS1 effector domain-binding protein 1) (Neb-1) (No arches homolog) Homo sapiens (Human) pre-mRNA cleavage required for polyadenylation [GO:0098789] GO:0003723; GO:0005654; GO:0005847; GO:0008270; GO:0043231; GO:0098789; GO:1990837 694 XM_029344605.2 580 433 312 660 607 Q9NZN8 1.21e-123 CCR4-NOT transcription complex subunit 2 (CCR4-associated factor 2) Homo sapiens (Human) negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; positive regulation of cytoplasmic mRNA processing body assembly [GO:0010606]; regulation of stem cell population maintenance [GO:2000036]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; RNA-mediated gene silencing [GO:0031047]; trophectodermal cell differentiation [GO:0001829] GO:0000122; GO:0000289; GO:0000932; GO:0001222; GO:0001829; GO:0003712; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0006357; GO:0010606; GO:0016020; GO:0030014; GO:0030015; GO:0031047; GO:0033147; GO:0090503; GO:2000036 695 XM_044318696.1 212 0 17 85 40 NA NA NA NA NA NA 696 XM_044308199.1 35 18 74 88 26 NA NA NA NA NA NA 697 XM_029327790.2 343 402 125 558 399 NA NA NA NA NA NA 698 XM_044322778.1 80 64 31 58 170 NA NA NA NA NA NA 699 XM_044323500.1 0 3 2 0 13 NA NA NA NA NA NA 700 XM_029328686.2 309 327 200 288 375 Q4KLT3 1.73e-137 Probable tRNA (uracil-O(2)-)-methyltransferase (EC 2.1.1.211) (Methyltransferase-like protein 19) Xenopus laevis (African clawed frog) NA GO:0005737; GO:0046872; GO:0052665 701 XM_044309751.1 0 38 2 8 0 P10079 0 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 702 XM_044309751.1 0 38 2 8 0 P10079 0 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 703 XM_044309751.1 0 38 2 8 0 P10079 0 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 704 XM_044309751.1 0 38 2 8 0 P10079 0 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 705 XM_044309751.1 0 38 2 8 0 P10079 0 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 706 XM_044328489.1 179 326 431 772 665 NA NA NA NA NA NA 707 XM_044326051.1 0 3 0 0 15 NA NA NA NA NA NA 708 XM_044326435.1 9 0 0 1 5 NA NA NA NA NA NA 709 XM_044308483.1 546 329 472 1012 1129 Q9ULL1 1.22e-94 Pleckstrin homology domain-containing family G member 1 Homo sapiens (Human) regulation of small GTPase mediated signal transduction [GO:0051056] GO:0005085; GO:0005654; GO:0005829; GO:0051056 710 XM_044322019.1 190 0 0 254 0 NA NA NA NA NA NA 711 XR_006395733.1 0 0 121 0 237 NA NA NA NA NA NA 712 XM_029348489.2 82 35 37 44 103 Q90744 3.13e-145 Alpha-N-acetylgalactosaminidase (EC 3.2.1.49) (Alpha-galactosidase B) Gallus gallus (Chicken) glycoside catabolic process [GO:0016139]; lipid metabolic process [GO:0006629]; oligosaccharide metabolic process [GO:0009311] GO:0004557; GO:0005737; GO:0005764; GO:0006629; GO:0008456; GO:0009311; GO:0016139 713 XM_044328558.1 680 442 483 906 1004 NA NA NA NA NA NA 714 XM_044315327.1 59 1005 76 216 75 NA NA NA NA NA NA 715 XM_044312245.1 66 44 46 34 49 Q6NVS5 6.77e-61 DDB1- and CUL4-associated factor 13 (WD repeat and SOF domain-containing protein 1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) protein ubiquitination [GO:0016567]; rRNA processing [GO:0006364] GO:0005730; GO:0006364; GO:0016567; GO:0080008; GO:1990904 716 XM_044318720.1 153 957 136 54 28 NA NA NA NA NA NA 717 XM_044325312.1 72 23 34 0 0 Q04786 4.45e-115 Beta-hexosaminidase (EC 3.2.1.52) (Beta-N-acetylhexosaminidase) (Chitobiase) (N-acetyl-beta-glucosaminidase) Vibrio vulnificus chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272] GO:0000272; GO:0004563; GO:0006032; GO:0030247; GO:0102148 718 XR_003826176.2 2 9 6 0 8 NA NA NA NA NA NA 719 XM_044308797.1 95 128 38 103 142 Q80XJ3 2.3e-86 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 720 XM_044308797.1 95 128 38 103 142 Q80XJ3 8.86e-61 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 721 XM_044308797.1 95 128 38 103 142 Q80XJ3 5.47e-57 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 722 XM_044308797.1 95 128 38 103 142 Q80XJ3 1.37e-55 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 723 XM_044308797.1 95 128 38 103 142 Q80XJ3 1.78e-54 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 724 XM_044308797.1 95 128 38 103 142 Q80XJ3 8.03e-52 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 725 XM_044308797.1 95 128 38 103 142 Q80XJ3 2.53e-48 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 726 XM_044308797.1 95 128 38 103 142 Q80XJ3 6.32e-46 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 727 XM_044308797.1 95 128 38 103 142 Q80XJ3 3.45e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 728 XM_044308797.1 95 128 38 103 142 Q80XJ3 6.49e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 729 XM_029355337.2 1583 1439 995 1906 2091 Q14AT5 0 Anoctamin-7 (New gene expressed in prostate homolog) (Transmembrane protein 16G) Mus musculus (Mouse) calcium activated galactosylceramide scrambling [GO:0061591]; calcium activated phosphatidylcholine scrambling [GO:0061590]; calcium activated phosphatidylserine scrambling [GO:0061589]; calcium activated phospholipid scrambling [GO:0061588]; chloride transmembrane transport [GO:1902476]; chloride transport [GO:0006821]; establishment of localization in cell [GO:0051649]; transmembrane transport [GO:0055085] GO:0005254; GO:0005783; GO:0005886; GO:0006821; GO:0017128; GO:0046983; GO:0051649; GO:0055085; GO:0061588; GO:0061589; GO:0061590; GO:0061591; GO:1902476 730 XM_044329155.1 0 0 0 85 0 Q9CZT4 8.33e-61 DNA-directed RNA polymerase III subunit RPC5 (RNA polymerase III subunit 5) (RNA polymerase III subunit C5) (Sex-lethal interactor homolog) (Sxl interactor) Mus musculus (Mouse) defense response to virus [GO:0051607]; DNA-templated transcription [GO:0006351]; innate immune response [GO:0045087] GO:0005654; GO:0005666; GO:0006351; GO:0045087; GO:0051607 731 XM_044321794.1 23 0 5 0 0 Q66IB8 6.91e-31 UPF0538 protein C2orf76 homolog Danio rerio (Zebrafish) (Brachydanio rerio) NA NA 732 XM_029352556.2 315 212 303 188 217 Q28I29 4.02e-53 tRNA-uridine aminocarboxypropyltransferase 1 (EC 2.5.1.25) (DTW domain-containing protein 1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) tRNA modification [GO:0006400] GO:0005634; GO:0006400; GO:0016432 733 XM_044319915.1 12 21 60 101 80 NA NA NA NA NA NA 734 XM_029329992.2 740 494 461 814 769 Q13569 3.55e-67 G/T mismatch-specific thymine DNA glycosylase (EC 3.2.2.29) (Thymine-DNA glycosylase) (hTDG) Homo sapiens (Human) base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; depyrimidination [GO:0045008]; DNA demethylation [GO:0080111]; epigenetic regulation of gene expression [GO:0040029]; mismatch repair [GO:0006298]; negative regulation of chromatin binding [GO:0035562]; negative regulation of protein binding [GO:0032091]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidative DNA demethylation [GO:0035511]; regulation of DNA N-glycosylase activity [GO:1902544]; regulation of embryonic development [GO:0045995] GO:0000122; GO:0000287; GO:0003676; GO:0003677; GO:0003684; GO:0003690; GO:0003712; GO:0004844; GO:0005080; GO:0005524; GO:0005634; GO:0005654; GO:0005886; GO:0006284; GO:0006285; GO:0006298; GO:0008263; GO:0016605; GO:0019104; GO:0019904; GO:0030983; GO:0031402; GO:0031404; GO:0032091; GO:0032183; GO:0035511; GO:0035562; GO:0040029; GO:0042803; GO:0043621; GO:0043739; GO:0045008; GO:0045995; GO:0080111; GO:0140297; GO:1902544 735 XM_029340252.2 249 140 170 213 295 P59101 2.69e-25 Basic helix-loop-helix transcription factor scleraxis Gallus gallus (Chicken) cellular response to BMP stimulus [GO:0071773]; cellular response to fibroblast growth factor stimulus [GO:0044344]; developmental process [GO:0032502]; regulation of transcription by RNA polymerase II [GO:0006357]; sclerotome development [GO:0061056]; tendon development [GO:0035989] GO:0000977; GO:0000981; GO:0005634; GO:0006357; GO:0032502; GO:0035989; GO:0044344; GO:0046983; GO:0061056; GO:0071773 736 XM_029339750.2 0 0 0 18 47 Q60564 7.17e-47 LIM homeobox transcription factor 1-beta (LIM/homeobox protein 1.2) (LMX-1.2) (LIM/homeobox protein LMX1B) Mesocricetus auratus (Golden hamster) system development [GO:0048731] GO:0000981; GO:0003677; GO:0005634; GO:0046872; GO:0048731 737 XM_029357590.2 1115 552 688 1595 1251 Q69Z89 8.77e-118 Ras-associating and dilute domain-containing protein Mus musculus (Mouse) neural crest cell migration [GO:0001755]; signal transduction [GO:0007165]; substrate adhesion-dependent cell spreading [GO:0034446] GO:0001755; GO:0005874; GO:0007165; GO:0032991; GO:0034446; GO:0051020 738 XM_029357225.2 69 13 0 42 83 P13908 5.58e-60 Neuronal acetylcholine receptor subunit non-alpha-2 (GFN-alpha-2) Carassius auratus (Goldfish) NA GO:0004888; GO:0022848; GO:0045211 739 XM_044308310.1 119 0 0 110 124 NA NA NA NA NA NA 740 XR_006397802.1 141 189 101 164 162 NA NA NA NA NA NA 741 XM_044327370.1 12 7 25 24 22 NA NA NA NA NA NA 742 XR_006393162.1 0 0 0 0 50 NA NA NA NA NA NA 743 XM_044311585.1 0 22 0 23 141 A7SGU6 1.44e-75 Proteasome assembly chaperone 2 Nematostella vectensis (Starlet sea anemone) proteasome assembly [GO:0043248] GO:0005634; GO:0005829; GO:0043248 744 XM_044325295.1 333 218 256 336 213 Q27084 1.92e-82 Tachylectin-2 (Lectin L10c) Tachypleus tridentatus (Japanese horseshoe crab) innate immune response [GO:0045087] GO:0005576; GO:0030246; GO:0045087 745 XM_044325295.1 333 218 256 336 213 Q27084 2.22e-65 Tachylectin-2 (Lectin L10c) Tachypleus tridentatus (Japanese horseshoe crab) innate immune response [GO:0045087] GO:0005576; GO:0030246; GO:0045087 746 XR_006397197.1 0 32 24 0 25 NA NA NA NA NA NA 747 XR_006391691.1 0 4 0 5 17 NA NA NA NA NA NA 748 XM_029324712.2 110 137 133 153 79 Q14191 6.81e-41 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN (DNA helicase, RecQ-like type 3) (RecQ protein-like 2) (Werner syndrome protein) [Includes: 3'-5' exonuclease (EC 3.1.-.-); ATP-dependent helicase (EC 3.6.4.12)] Homo sapiens (Human) aging [GO:0007568]; base-excision repair [GO:0006284]; brain development [GO:0007420]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; cellular response to starvation [GO:0009267]; cellular senescence [GO:0090398]; DNA duplex unwinding [GO:0032508]; DNA metabolic process [GO:0006259]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; G-quadruplex DNA unwinding [GO:0044806]; multicellular organism aging [GO:0010259]; positive regulation of hydrolase activity [GO:0051345]; positive regulation of strand invasion [GO:0098530]; protein localization to nucleolus [GO:1902570]; regulation of growth rate [GO:0040009]; replication fork processing [GO:0031297]; replicative senescence [GO:0090399]; response to oxidative stress [GO:0006979]; response to UV-C [GO:0010225]; t-circle formation [GO:0090656]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; telomeric D-loop disassembly [GO:0061820] GO:0000287; GO:0000400; GO:0000403; GO:0000405; GO:0000723; GO:0000724; GO:0000731; GO:0000781; GO:0003677; GO:0003678; GO:0003682; GO:0004527; GO:0005524; GO:0005634; GO:0005654; GO:0005657; GO:0005694; GO:0005730; GO:0005737; GO:0005813; GO:0006259; GO:0006260; GO:0006268; GO:0006281; GO:0006284; GO:0006302; GO:0006310; GO:0006974; GO:0006979; GO:0007420; GO:0007568; GO:0008408; GO:0009267; GO:0009378; GO:0010225; GO:0010259; GO:0016607; GO:0016887; GO:0030145; GO:0031297; GO:0032201; GO:0032405; GO:0032508; GO:0040009; GO:0042803; GO:0043005; GO:0043138; GO:0044806; GO:0044877; GO:0051345; GO:0051880; GO:0061749; GO:0061820; GO:0061821; GO:0061849; GO:0070337; GO:0071480; GO:0090398; GO:0090399; GO:0090656; GO:0098530; GO:1902570; GO:1905773 749 XM_029349324.2 323 358 217 427 516 Q9Y222 1.11e-129 Cyclin-D-binding Myb-like transcription factor 1 (hDMTF1) (Cyclin-D-interacting Myb-like protein 1) (hDMP1) Homo sapiens (Human) cell cycle [GO:0007049]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000976; GO:0000978; GO:0000981; GO:0001228; GO:0003700; GO:0005634; GO:0005654; GO:0005829; GO:0006355; GO:0006357; GO:0007049 750 XM_044310416.1 0 0 0 4 12 NA NA NA NA NA NA 751 XM_044310248.1 0 2 11 0 0 NA NA NA NA NA NA 752 XM_044313679.1 6 0 0 120 12 NA NA NA NA NA NA 753 XM_029347926.2 1669 1140 941 1906 1879 P28271 0 Cytoplasmic aconitate hydratase (Aconitase) (EC 4.2.1.3) (Citrate hydro-lyase) (Iron regulatory protein 1) (IRP1) (Iron-responsive element-binding protein 1) (IRE-BP 1) Mus musculus (Mouse) cellular iron ion homeostasis [GO:0006879]; citrate metabolic process [GO:0006101]; intestinal absorption [GO:0050892]; post-embryonic development [GO:0009791]; regulation of gene expression [GO:0010468]; regulation of translation [GO:0006417]; response to iron(II) ion [GO:0010040]; tricarboxylic acid cycle [GO:0006099] GO:0003723; GO:0003994; GO:0005737; GO:0005739; GO:0005783; GO:0005794; GO:0005829; GO:0006099; GO:0006101; GO:0006417; GO:0006879; GO:0009791; GO:0010040; GO:0010468; GO:0030350; GO:0043231; GO:0046872; GO:0047780; GO:0048027; GO:0050892; GO:0051536; GO:0051538; GO:0051539 754 XM_044311118.1 1192 45 803 283 5 NA NA NA NA NA NA 755 XM_044324339.1 0 0 62 16 87 NA NA NA NA NA NA 756 XR_006394405.1 42 0 26 0 127 NA NA NA NA NA NA 757 XM_044323393.1 11 10 4 4 1 NA NA NA NA NA NA 758 XM_029355427.2 234 258 174 405 471 Q501I9 3.13e-51 Solute carrier family 49 member 4 homolog (Disrupted in renal carcinoma protein 2 homolog) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005765; GO:0022857 759 XM_044313227.1 2222 1188 943 1962 1925 Q5ZKV8 0 Kinesin-like protein KIF2A Gallus gallus (Chicken) cell differentiation [GO:0030154]; cell division [GO:0051301]; microtubule-based movement [GO:0007018]; mitotic spindle organization [GO:0007052]; nervous system development [GO:0007399] GO:0000922; GO:0003777; GO:0005524; GO:0005737; GO:0005813; GO:0005819; GO:0005871; GO:0005874; GO:0007018; GO:0007052; GO:0007399; GO:0008017; GO:0016887; GO:0030154; GO:0051301 760 XM_029337503.2 468 241 63 495 713 P17844 0 Probable ATP-dependent RNA helicase DDX5 (EC 3.6.4.13) (DEAD box protein 5) (RNA helicase p68) Homo sapiens (Human) alternative mRNA splicing, via spliceosome [GO:0000380]; androgen receptor signaling pathway [GO:0030521]; BMP signaling pathway [GO:0030509]; epithelial to mesenchymal transition [GO:0001837]; intracellular estrogen receptor signaling pathway [GO:0030520]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; miRNA transcription [GO:0061614]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transcription [GO:0009299]; myoblast differentiation [GO:0045445]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nuclear-transcribed mRNA catabolic process [GO:0000956]; positive regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043517]; primary miRNA processing [GO:0031053]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of osteoblast differentiation [GO:0045667]; regulation of skeletal muscle cell differentiation [GO:2001014]; regulation of transcription by RNA polymerase II [GO:0006357]; rhythmic process [GO:0048511] GO:0000122; GO:0000380; GO:0000381; GO:0000398; GO:0000956; GO:0001837; GO:0003723; GO:0003724; GO:0003730; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005829; GO:0006357; GO:0009299; GO:0016020; GO:0016607; GO:0016887; GO:0030509; GO:0030520; GO:0030521; GO:0031053; GO:0035500; GO:0036002; GO:0043021; GO:0043517; GO:0045445; GO:0045667; GO:0046332; GO:0048511; GO:0050681; GO:0060765; GO:0061614; GO:0070062; GO:0070412; GO:0070878; GO:0071013; GO:0072332; GO:1990841; GO:1990904; GO:2001014 761 XM_029333175.2 0 0 0 7 0 P10079 8.54e-75 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 762 XM_029333175.2 0 0 0 7 0 P10079 1.02e-74 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 763 XM_029333175.2 0 0 0 7 0 P10079 3.62e-73 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 764 XM_029333175.2 0 0 0 7 0 P10079 3.13e-69 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 765 XM_029333175.2 0 0 0 7 0 P10079 5.76e-69 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 766 XM_029333175.2 0 0 0 7 0 P10079 1.14e-68 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 767 XM_029333175.2 0 0 0 7 0 P10079 1.66e-68 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 768 XM_029333175.2 0 0 0 7 0 P10079 2.59e-68 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 769 XM_029333175.2 0 0 0 7 0 P10079 3.32e-68 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 770 XM_029333175.2 0 0 0 7 0 P10079 3.07e-67 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 771 XM_029333175.2 0 0 0 7 0 P10079 1.43e-66 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 772 XM_029333175.2 0 0 0 7 0 P10079 3.22e-66 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 773 XM_029333175.2 0 0 0 7 0 P10079 1.06e-65 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 774 XM_029333175.2 0 0 0 7 0 P10079 3.74e-57 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 775 XM_029333175.2 0 0 0 7 0 P10079 4.61e-47 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 776 XM_044323751.1 53 2 27 19 138 P08183 2.74e-104 ATP-dependent translocase ABCB1 (ATP-binding cassette sub-family B member 1) (Multidrug resistance protein 1) (EC 7.6.2.2) (P-glycoprotein 1) (Phospholipid transporter ABCB1) (EC 7.6.2.1) (CD antigen CD243) Homo sapiens (Human) carboxylic acid transmembrane transport [GO:1905039]; ceramide translocation [GO:0099040]; export across plasma membrane [GO:0140115]; G2/M transition of mitotic cell cycle [GO:0000086]; phospholipid translocation [GO:0045332]; positive regulation of anion channel activity [GO:1901529]; regulation of chloride transport [GO:2001225]; regulation of response to osmotic stress [GO:0047484]; response to xenobiotic stimulus [GO:0009410]; stem cell proliferation [GO:0072089]; terpenoid transport [GO:0046865]; transepithelial transport [GO:0070633]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; xenobiotic detoxification by transmembrane export across the plasma membrane [GO:1990961]; xenobiotic metabolic process [GO:0006805]; xenobiotic transport across blood-brain barrier [GO:1990962] GO:0000086; GO:0005524; GO:0005654; GO:0005737; GO:0005886; GO:0006805; GO:0008559; GO:0009410; GO:0009986; GO:0015562; GO:0016020; GO:0016324; GO:0016887; GO:0022857; GO:0031625; GO:0042626; GO:0042910; GO:0045332; GO:0046865; GO:0046943; GO:0047484; GO:0055085; GO:0070062; GO:0070633; GO:0072089; GO:0090554; GO:0090555; GO:0098591; GO:0099038; GO:0099040; GO:0140115; GO:0140328; GO:0150104; GO:1901529; GO:1905039; GO:1990961; GO:1990962; GO:2001225 777 XM_044323751.1 53 2 27 19 138 P08183 2.06e-63 ATP-dependent translocase ABCB1 (ATP-binding cassette sub-family B member 1) (Multidrug resistance protein 1) (EC 7.6.2.2) (P-glycoprotein 1) (Phospholipid transporter ABCB1) (EC 7.6.2.1) (CD antigen CD243) Homo sapiens (Human) carboxylic acid transmembrane transport [GO:1905039]; ceramide translocation [GO:0099040]; export across plasma membrane [GO:0140115]; G2/M transition of mitotic cell cycle [GO:0000086]; phospholipid translocation [GO:0045332]; positive regulation of anion channel activity [GO:1901529]; regulation of chloride transport [GO:2001225]; regulation of response to osmotic stress [GO:0047484]; response to xenobiotic stimulus [GO:0009410]; stem cell proliferation [GO:0072089]; terpenoid transport [GO:0046865]; transepithelial transport [GO:0070633]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; xenobiotic detoxification by transmembrane export across the plasma membrane [GO:1990961]; xenobiotic metabolic process [GO:0006805]; xenobiotic transport across blood-brain barrier [GO:1990962] GO:0000086; GO:0005524; GO:0005654; GO:0005737; GO:0005886; GO:0006805; GO:0008559; GO:0009410; GO:0009986; GO:0015562; GO:0016020; GO:0016324; GO:0016887; GO:0022857; GO:0031625; GO:0042626; GO:0042910; GO:0045332; GO:0046865; GO:0046943; GO:0047484; GO:0055085; GO:0070062; GO:0070633; GO:0072089; GO:0090554; GO:0090555; GO:0098591; GO:0099038; GO:0099040; GO:0140115; GO:0140328; GO:0150104; GO:1901529; GO:1905039; GO:1990961; GO:1990962; GO:2001225 778 XM_044323751.1 53 2 27 19 138 P08183 2.05e-48 ATP-dependent translocase ABCB1 (ATP-binding cassette sub-family B member 1) (Multidrug resistance protein 1) (EC 7.6.2.2) (P-glycoprotein 1) (Phospholipid transporter ABCB1) (EC 7.6.2.1) (CD antigen CD243) Homo sapiens (Human) carboxylic acid transmembrane transport [GO:1905039]; ceramide translocation [GO:0099040]; export across plasma membrane [GO:0140115]; G2/M transition of mitotic cell cycle [GO:0000086]; phospholipid translocation [GO:0045332]; positive regulation of anion channel activity [GO:1901529]; regulation of chloride transport [GO:2001225]; regulation of response to osmotic stress [GO:0047484]; response to xenobiotic stimulus [GO:0009410]; stem cell proliferation [GO:0072089]; terpenoid transport [GO:0046865]; transepithelial transport [GO:0070633]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; xenobiotic detoxification by transmembrane export across the plasma membrane [GO:1990961]; xenobiotic metabolic process [GO:0006805]; xenobiotic transport across blood-brain barrier [GO:1990962] GO:0000086; GO:0005524; GO:0005654; GO:0005737; GO:0005886; GO:0006805; GO:0008559; GO:0009410; GO:0009986; GO:0015562; GO:0016020; GO:0016324; GO:0016887; GO:0022857; GO:0031625; GO:0042626; GO:0042910; GO:0045332; GO:0046865; GO:0046943; GO:0047484; GO:0055085; GO:0070062; GO:0070633; GO:0072089; GO:0090554; GO:0090555; GO:0098591; GO:0099038; GO:0099040; GO:0140115; GO:0140328; GO:0150104; GO:1901529; GO:1905039; GO:1990961; GO:1990962; GO:2001225 779 XM_044323751.1 53 2 27 19 138 P08183 1.6e-36 ATP-dependent translocase ABCB1 (ATP-binding cassette sub-family B member 1) (Multidrug resistance protein 1) (EC 7.6.2.2) (P-glycoprotein 1) (Phospholipid transporter ABCB1) (EC 7.6.2.1) (CD antigen CD243) Homo sapiens (Human) carboxylic acid transmembrane transport [GO:1905039]; ceramide translocation [GO:0099040]; export across plasma membrane [GO:0140115]; G2/M transition of mitotic cell cycle [GO:0000086]; phospholipid translocation [GO:0045332]; positive regulation of anion channel activity [GO:1901529]; regulation of chloride transport [GO:2001225]; regulation of response to osmotic stress [GO:0047484]; response to xenobiotic stimulus [GO:0009410]; stem cell proliferation [GO:0072089]; terpenoid transport [GO:0046865]; transepithelial transport [GO:0070633]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; xenobiotic detoxification by transmembrane export across the plasma membrane [GO:1990961]; xenobiotic metabolic process [GO:0006805]; xenobiotic transport across blood-brain barrier [GO:1990962] GO:0000086; GO:0005524; GO:0005654; GO:0005737; GO:0005886; GO:0006805; GO:0008559; GO:0009410; GO:0009986; GO:0015562; GO:0016020; GO:0016324; GO:0016887; GO:0022857; GO:0031625; GO:0042626; GO:0042910; GO:0045332; GO:0046865; GO:0046943; GO:0047484; GO:0055085; GO:0070062; GO:0070633; GO:0072089; GO:0090554; GO:0090555; GO:0098591; GO:0099038; GO:0099040; GO:0140115; GO:0140328; GO:0150104; GO:1901529; GO:1905039; GO:1990961; GO:1990962; GO:2001225 780 XM_029354445.2 0 0 0 0 12 NA NA NA NA NA NA 781 XM_029348429.2 616 663 720 665 679 P36410 2.05e-31 Ras-related protein Rab-14 (Rab4-like GTPase) Dictyostelium discoideum (Social amoeba) contractile vacuole organization [GO:0033298]; defense response to bacterium [GO:0042742]; endocytic recycling [GO:0032456]; Golgi to endosome transport [GO:0006895]; intracellular protein transport [GO:0006886]; phagolysosome assembly involved in apoptotic cell clearance [GO:0090387]; regulation of endosomal vesicle fusion [GO:1905364]; regulation of pinocytosis [GO:0048548]; response to osmotic stress [GO:0006970] GO:0003924; GO:0005525; GO:0005764; GO:0005765; GO:0005769; GO:0005802; GO:0005811; GO:0005829; GO:0006886; GO:0006895; GO:0006970; GO:0012505; GO:0031164; GO:0032456; GO:0033298; GO:0042742; GO:0045335; GO:0048548; GO:0055037; GO:0062160; GO:0090387; GO:0140220; GO:1905364 782 XM_044313500.1 38 42 4 19 0 P27590 2.33e-40 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Rattus norvegicus (Rat) antibacterial innate immune response [GO:0140367]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; autophagy [GO:0006914]; calcium ion homeostasis [GO:0055074]; cellular calcium ion homeostasis [GO:0006874]; cellular chloride ion homeostasis [GO:0030644]; cellular phosphate ion homeostasis [GO:0030643]; cellular response to unfolded protein [GO:0034620]; cellular sodium ion homeostasis [GO:0006883]; chaperone-mediated protein folding [GO:0061077]; chemical homeostasis [GO:0048878]; chloride ion homeostasis [GO:0055064]; citric acid secretion [GO:0046720]; collecting duct development [GO:0072044]; connective tissue replacement [GO:0097709]; creatinine homeostasis [GO:0097273]; defense response to Gram-negative bacterium [GO:0050829]; endoplasmic reticulum organization [GO:0007029]; gene expression [GO:0010467]; glomerular filtration [GO:0003094]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; ion homeostasis [GO:0050801]; juxtaglomerular apparatus development [GO:0072051]; kidney development [GO:0001822]; leukocyte cell-cell adhesion [GO:0007159]; lipid metabolic process [GO:0006629]; loop of Henle development [GO:0072070]; metanephric ascending thin limb development [GO:0072218]; metanephric distal convoluted tubule development [GO:0072221]; metanephric thick ascending limb development [GO:0072233]; micturition [GO:0060073]; multicellular organismal homeostasis [GO:0048871]; multicellular organismal response to stress [GO:0033555]; neutrophil migration [GO:1990266]; organ or tissue specific immune response [GO:0002251]; peptidyl-threonine phosphorylation [GO:0018107]; phosphate ion homeostasis [GO:0055062]; potassium ion homeostasis [GO:0055075]; protein localization to vacuole [GO:0072665]; protein phosphorylation [GO:0006468]; protein transport into plasma membrane raft [GO:0044861]; regulation of blood pressure [GO:0008217]; regulation of protein transport [GO:0051223]; regulation of urine volume [GO:0035809]; renal sodium ion absorption [GO:0070294]; renal urate salt excretion [GO:0097744]; renal water homeostasis [GO:0003091]; response to endoplasmic reticulum stress [GO:0034976]; response to lipopolysaccharide [GO:0032496]; response to organic substance [GO:0010033]; response to unfolded protein [GO:0006986]; response to water deprivation [GO:0009414]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; sodium ion homeostasis [GO:0055078]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; ubiquitin-dependent ERAD pathway [GO:0030433]; urate transport [GO:0015747]; urea transmembrane transport [GO:0071918]; water homeostasis [GO:0030104] GO:0000922; GO:0001822; GO:0002251; GO:0003091; GO:0003094; GO:0005201; GO:0005509; GO:0005615; GO:0005783; GO:0005794; GO:0005886; GO:0005929; GO:0006468; GO:0006629; GO:0006874; GO:0006883; GO:0006914; GO:0006915; GO:0006954; GO:0006986; GO:0007029; GO:0007157; GO:0007159; GO:0008217; GO:0008380; GO:0009410; GO:0009414; GO:0009986; GO:0010033; GO:0010467; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0018107; GO:0019864; GO:0030104; GO:0030433; GO:0030643; GO:0030644; GO:0031410; GO:0032496; GO:0033209; GO:0033555; GO:0034620; GO:0034976; GO:0035809; GO:0044861; GO:0045121; GO:0045177; GO:0046720; GO:0048871; GO:0048878; GO:0050801; GO:0050829; GO:0051223; GO:0055062; GO:0055064; GO:0055074; GO:0055075; GO:0055078; GO:0060073; GO:0060170; GO:0061077; GO:0070294; GO:0071918; GO:0072044; GO:0072051; GO:0072070; GO:0072218; GO:0072221; GO:0072233; GO:0072665; GO:0097190; GO:0097273; GO:0097709; GO:0097744; GO:0140367; GO:1990266 783 XM_044326109.1 10 0 4 8 2 NA NA NA NA NA NA 784 XM_029350244.2 0 0 0 0 96 NA NA NA NA NA NA 785 XM_029352105.2 871 701 669 2922 2635 Q9BQS8 1.8e-42 FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7) Homo sapiens (Human) plus-end-directed vesicle transport along microtubule [GO:0072383]; positive regulation of autophagosome maturation [GO:1901098] GO:0005764; GO:0005770; GO:0005776; GO:0005794; GO:0016020; GO:0043231; GO:0046872; GO:0072383; GO:1901098 786 XM_029352105.2 871 701 669 2922 2635 Q9BQS8 8.34e-30 FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7) Homo sapiens (Human) plus-end-directed vesicle transport along microtubule [GO:0072383]; positive regulation of autophagosome maturation [GO:1901098] GO:0005764; GO:0005770; GO:0005776; GO:0005794; GO:0016020; GO:0043231; GO:0046872; GO:0072383; GO:1901098 787 XM_044325720.1 321 297 262 394 262 NA NA NA NA NA NA 788 XM_029358324.2 1714 1191 626 1731 1360 Q6DJ06 5.99e-54 LIM domain transcription factor LMO4.2 (LIM domain only protein 4.2) (LMO-4.2) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell differentiation [GO:0030154]; gastrulation [GO:0007369]; mesoderm development [GO:0007498]; negative regulation of neuron differentiation [GO:0045665]; nervous system development [GO:0007399]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0003712; GO:0007369; GO:0007399; GO:0007498; GO:0030154; GO:0045665; GO:0045944; GO:0046872 789 XM_044324416.1 207 124 151 41 385 NA NA NA NA NA NA 790 XR_006391650.1 164 87 10 28 46 NA NA NA NA NA NA 791 XM_044323036.1 361 198 195 257 538 Q6P1L5 6.13e-25 Protein FAM117B (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 13 protein) Homo sapiens (Human) NA NA 792 XM_044318111.1 132 134 61 90 140 NA NA NA NA NA NA 793 XM_029344499.2 823 594 448 658 782 NA NA NA NA NA NA 794 XM_029336907.2 6 0 18 21 27 Q9IAK8 4.19e-90 T-box transcription factor TBX5-A (zftbx5a) (T-box protein 5) (zTbx5) Danio rerio (Zebrafish) (Brachydanio rerio) animal organ morphogenesis [GO:0009887]; atrial ventricular junction remodeling [GO:0003294]; atrioventricular canal development [GO:0036302]; atrioventricular valve formation [GO:0003190]; cardiac left ventricle formation [GO:0003218]; cardiac muscle cell differentiation [GO:0055007]; cardiac muscle tissue regeneration [GO:0061026]; cell fate specification [GO:0001708]; DNA-templated transcription [GO:0006351]; embryonic heart tube development [GO:0035050]; embryonic heart tube morphogenesis [GO:0003143]; embryonic pectoral fin morphogenesis [GO:0035118]; heart development [GO:0007507]; heart jogging [GO:0003146]; heart looping [GO:0001947]; heart morphogenesis [GO:0003007]; limb bud formation [GO:0060174]; optic nerve development [GO:0021554]; pattern specification process [GO:0007389]; pectoral fin development [GO:0033339]; pectoral fin morphogenesis [GO:0035138]; pericardium morphogenesis [GO:0003344]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proepicardium development [GO:0003342]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; retina morphogenesis in camera-type eye [GO:0060042] GO:0000978; GO:0000981; GO:0001708; GO:0001947; GO:0003007; GO:0003143; GO:0003146; GO:0003190; GO:0003218; GO:0003294; GO:0003342; GO:0003344; GO:0003700; GO:0005634; GO:0005737; GO:0006351; GO:0006355; GO:0006357; GO:0007389; GO:0007507; GO:0009887; GO:0015629; GO:0021554; GO:0032991; GO:0032993; GO:0033339; GO:0035050; GO:0035118; GO:0035138; GO:0036302; GO:0043565; GO:0045893; GO:0045944; GO:0055007; GO:0060042; GO:0060174; GO:0061026 795 XM_029334505.2 3353 2108 1225 2622 1526 Q9PVM0 1.84e-31 Homeobox protein otx5-A (Orthodenticle homolog 5-A) (Xotx5) Xenopus laevis (African clawed frog) anterior/posterior pattern specification [GO:0009952]; eye photoreceptor cell fate commitment [GO:0042706]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000981; GO:0003677; GO:0005634; GO:0009952; GO:0042706; GO:0045944 796 XM_044318225.1 96 19 0 0 97 P42325 2.79e-110 Neurocalcin homolog (DrosNCa) Drosophila melanogaster (Fruit fly) negative regulation of neuronal signal transduction [GO:1902848]; positive regulation of circadian sleep/wake cycle, sleep [GO:0045938] GO:0005509; GO:0045938; GO:1902848 797 XR_006392400.1 69 77 6 1 2 NA NA NA NA NA NA 798 XM_029352131.2 574 312 350 330 343 A6QQL0 3.79e-58 Solute carrier family 15 member 4 (Peptide/histidine transporter 1) Bos taurus (Bovine) dipeptide import across plasma membrane [GO:0140206]; histidine transport [GO:0015817]; innate immune response [GO:0045087]; L-histidine transmembrane export from vacuole [GO:0089708]; mast cell homeostasis [GO:0033023]; peptidoglycan transport [GO:0015835]; positive regulation of innate immune response [GO:0045089]; positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [GO:0070430]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of toll-like receptor 7 signaling pathway [GO:0034157]; positive regulation of toll-like receptor 8 signaling pathway [GO:0034161]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; protein transport [GO:0015031]; regulation of isotype switching to IgG isotypes [GO:0048302]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424]; transmembrane transport [GO:0055085] GO:0005290; GO:0005765; GO:0015031; GO:0015333; GO:0015647; GO:0015817; GO:0015835; GO:0016020; GO:0022857; GO:0031901; GO:0033023; GO:0034157; GO:0034161; GO:0034165; GO:0036020; GO:0045087; GO:0045089; GO:0048302; GO:0055085; GO:0070424; GO:0070430; GO:0070434; GO:0071916; GO:0089708; GO:0140206 799 XM_029345484.2 408 333 283 370 536 Q6PC30 0 COP9 signalosome complex subunit 5 (Signalosome subunit 5) (EC 3.4.-.-) Danio rerio (Zebrafish) (Brachydanio rerio) negative regulation of apoptotic process [GO:0043066]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; protein deneddylation [GO:0000338]; vestibular receptor cell development [GO:0060118] GO:0000338; GO:0005634; GO:0005737; GO:0005829; GO:0008021; GO:0008180; GO:0008237; GO:0019784; GO:0043066; GO:0046872; GO:0048471; GO:0051091; GO:0060118 800 XM_044313851.1 3 11 0 60 36 NA NA NA NA NA NA 801 XM_029350754.2 68 0 26 66 0 P51029 5.45e-71 Protein Wnt-8b Danio rerio (Zebrafish) (Brachydanio rerio) canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; commissural neuron axon guidance [GO:0071679]; embryonic pattern specification [GO:0009880]; eye development [GO:0001654]; eye field cell fate commitment involved in camera-type eye formation [GO:0060898]; forebrain development [GO:0030900]; forebrain neuron differentiation [GO:0021879]; hypothalamus development [GO:0021854]; negative regulation of anterior neural cell fate commitment of the neural plate by Wnt signaling pathway [GO:0022002]; neuron differentiation [GO:0030182]; otic placode formation [GO:0043049]; sensory epithelium regeneration [GO:0070654] GO:0001654; GO:0005109; GO:0005125; GO:0005615; GO:0009880; GO:0021854; GO:0021879; GO:0022002; GO:0030182; GO:0030900; GO:0043049; GO:0045165; GO:0060070; GO:0060898; GO:0070654; GO:0071679 802 XR_006395844.1 0 0 13 1 12 NA NA NA NA NA NA 803 XM_044323870.1 2 3 20 5 5 NA NA NA NA NA NA 804 XM_044326689.1 0 0 6 0 10 NA NA NA NA NA NA 805 XM_029324871.2 3361 2374 2130 3525 3535 Q5R5X3 0 Pumilio homolog 1 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) adult locomotory behavior [GO:0008344]; miRNA processing [GO:0035196]; mRNA destabilization [GO:0061157]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; post-transcriptional gene silencing [GO:0016441]; post-transcriptional regulation of gene expression [GO:0010608]; regulation of cell cycle [GO:0051726]; regulation of chromosome segregation [GO:0051983]; regulation of mRNA stability [GO:0043488]; spermatogenesis [GO:0007283]; stem cell differentiation [GO:0048863] GO:0000932; GO:0003730; GO:0005737; GO:0007283; GO:0008344; GO:0010608; GO:0016441; GO:0035196; GO:0043488; GO:0048863; GO:0051726; GO:0051983; GO:0061157; GO:2000637 806 XM_029324871.2 3361 2374 2130 3525 3535 Q5R5X3 1.48e-27 Pumilio homolog 1 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) adult locomotory behavior [GO:0008344]; miRNA processing [GO:0035196]; mRNA destabilization [GO:0061157]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; post-transcriptional gene silencing [GO:0016441]; post-transcriptional regulation of gene expression [GO:0010608]; regulation of cell cycle [GO:0051726]; regulation of chromosome segregation [GO:0051983]; regulation of mRNA stability [GO:0043488]; spermatogenesis [GO:0007283]; stem cell differentiation [GO:0048863] GO:0000932; GO:0003730; GO:0005737; GO:0007283; GO:0008344; GO:0010608; GO:0016441; GO:0035196; GO:0043488; GO:0048863; GO:0051726; GO:0051983; GO:0061157; GO:2000637 807 XM_044317734.1 136 53 63 23 49 P34147 3.55e-150 Rho-related protein racA Dictyostelium discoideum (Social amoeba) actin filament organization [GO:0007015]; cortical cytoskeleton organization [GO:0030865]; establishment or maintenance of cell polarity [GO:0007163]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; response to bacterium [GO:0009617]; small GTPase mediated signal transduction [GO:0007264] GO:0003924; GO:0005525; GO:0005856; GO:0005886; GO:0005938; GO:0007015; GO:0007163; GO:0007264; GO:0008360; GO:0009617; GO:0019901; GO:0030865; GO:0031410; GO:0032956; GO:0042995 808 XM_044321365.1 313 39 40 151 99 Q5VXM1 5.8e-29 CUB domain-containing protein 2 Homo sapiens (Human) NA GO:0005576 809 XM_029347305.2 3 5 23 2 5 NA NA NA NA NA NA 810 XM_029336675.2 10 0 5 0 18 O57460 3.41e-28 Dorsal-ventral patterning tolloid-like protein 1 (EC 3.4.24.-) (Mini fin protein) Danio rerio (Zebrafish) (Brachydanio rerio) blood vessel development [GO:0001568]; determination of ventral identity [GO:0048264]; dorsal/ventral pattern formation [GO:0009953]; embryonic caudal fin morphogenesis [GO:0035124]; embryonic hemopoiesis [GO:0035162]; endothelial cell development [GO:0001885]; mesoderm formation [GO:0001707]; positive regulation of BMP signaling pathway [GO:0030513]; post-anal tail morphogenesis [GO:0036342]; protein processing [GO:0016485]; proteolysis [GO:0006508] GO:0001568; GO:0001707; GO:0001885; GO:0004222; GO:0005509; GO:0005576; GO:0005615; GO:0006508; GO:0008233; GO:0008237; GO:0008270; GO:0009953; GO:0016485; GO:0030513; GO:0035124; GO:0035162; GO:0036342; GO:0048264 811 XM_029336675.2 10 0 5 0 18 O57460 1.26e-23 Dorsal-ventral patterning tolloid-like protein 1 (EC 3.4.24.-) (Mini fin protein) Danio rerio (Zebrafish) (Brachydanio rerio) blood vessel development [GO:0001568]; determination of ventral identity [GO:0048264]; dorsal/ventral pattern formation [GO:0009953]; embryonic caudal fin morphogenesis [GO:0035124]; embryonic hemopoiesis [GO:0035162]; endothelial cell development [GO:0001885]; mesoderm formation [GO:0001707]; positive regulation of BMP signaling pathway [GO:0030513]; post-anal tail morphogenesis [GO:0036342]; protein processing [GO:0016485]; proteolysis [GO:0006508] GO:0001568; GO:0001707; GO:0001885; GO:0004222; GO:0005509; GO:0005576; GO:0005615; GO:0006508; GO:0008233; GO:0008237; GO:0008270; GO:0009953; GO:0016485; GO:0030513; GO:0035124; GO:0035162; GO:0036342; GO:0048264 812 XR_003824760.2 80 101 75 207 117 NA NA NA NA NA NA 813 XM_029355767.2 124 4 68 39 17 NA NA NA NA NA NA 814 XM_044318999.1 2624 1792 1333 2609 6865 Q5R7J9 0 Eukaryotic translation initiation factor 4 gamma 2 (eIF-4-gamma 2) (eIF-4G 2) (eIF4G 2) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) regulation of translational initiation [GO:0006446] GO:0003723; GO:0003743; GO:0006446; GO:0008135; GO:0016281 815 XM_044324216.1 11 0 28 59 55 P38661 2.19e-48 Probable protein disulfide-isomerase A6 (EC 5.3.4.1) (P5) Medicago sativa (Alfalfa) NA GO:0003756; GO:0005788 816 XR_006394861.1 55 7 27 14 34 NA NA NA NA NA NA 817 XM_029358714.2 100 122 39 131 60 Q9GYZ0 0 Kinesin-like protein KIF15 (Kinesin-related protein KRP180) Strongylocentrotus purpuratus (Purple sea urchin) microtubule-based movement [GO:0007018]; regulation of mitotic spindle assembly [GO:1901673] GO:0003777; GO:0005524; GO:0005737; GO:0005819; GO:0005871; GO:0005874; GO:0007018; GO:0008017; GO:0016887; GO:1901673 818 XM_029330065.2 35 17 16 37 50 NA NA NA NA NA NA 819 XM_044314433.1 0 3 0 59 2 NA NA NA NA NA NA 820 XM_044327857.1 71 9 11 89 32 NA NA NA NA NA NA 821 XM_044312329.1 24 0 36 66 0 NA NA NA NA NA NA 822 XM_044317680.1 0 30 0 45 97 NA NA NA NA NA NA 823 XM_029342847.2 85 12 82 164 0 P16444 4.32e-107 Dipeptidase 1 (EC 3.4.13.19) (Beta-lactamase) (EC 3.5.2.6) (Dehydropeptidase-I) (Microsomal dipeptidase) (Renal dipeptidase) (hRDP) Homo sapiens (Human) antibiotic metabolic process [GO:0016999]; cellular response to calcium ion [GO:0071277]; cellular response to nitric oxide [GO:0071732]; cellular response to xenobiotic stimulus [GO:0071466]; glutathione catabolic process [GO:0006751]; glutathione metabolic process [GO:0006749]; homocysteine metabolic process [GO:0050667]; inflammatory response [GO:0006954]; lactam catabolic process [GO:0072340]; leukotriene D4 catabolic process [GO:1901749]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell migration [GO:0030336]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; neutrophil chemotaxis [GO:0030593]; proteolysis [GO:0006508] GO:0005615; GO:0005654; GO:0005886; GO:0006508; GO:0006749; GO:0006751; GO:0006954; GO:0008235; GO:0008270; GO:0008800; GO:0016324; GO:0016805; GO:0016999; GO:0030054; GO:0030336; GO:0030593; GO:0031528; GO:0034235; GO:0043027; GO:0043066; GO:0043154; GO:0045177; GO:0050667; GO:0070062; GO:0070573; GO:0071277; GO:0071466; GO:0071732; GO:0072340; GO:0072341; GO:1901749 824 XM_029328935.2 1843 1098 1088 1560 1660 P27986 4.69e-88 Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha) Homo sapiens (Human) B cell differentiation [GO:0030183]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to UV [GO:0034644]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; growth hormone receptor signaling pathway [GO:0060396]; immune response [GO:0006955]; insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; myeloid leukocyte migration [GO:0097529]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of stress fiber assembly [GO:0051497]; osteoclast differentiation [GO:0030316]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol phosphate biosynthetic process [GO:0046854]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of focal adhesion disassembly [GO:0120183]; positive regulation of glucose import [GO:0046326]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of RNA splicing [GO:0033120]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; protein import into nucleus [GO:0006606]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of phosphatidylinositol 3-kinase activity [GO:0043551]; response to endoplasmic reticulum stress [GO:0034976]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell differentiation [GO:0030217]; transcription by RNA polymerase II [GO:0006366] GO:0001678; GO:0001784; GO:0001953; GO:0002687; GO:0005068; GO:0005158; GO:0005159; GO:0005168; GO:0005634; GO:0005737; GO:0005801; GO:0005829; GO:0005886; GO:0005911; GO:0005942; GO:0005943; GO:0006366; GO:0006468; GO:0006606; GO:0006955; GO:0008286; GO:0008625; GO:0008630; GO:0010592; GO:0014065; GO:0016020; GO:0019903; GO:0030183; GO:0030217; GO:0030316; GO:0032760; GO:0032869; GO:0033120; GO:0034446; GO:0034644; GO:0034976; GO:0035014; GO:0036312; GO:0042307; GO:0043066; GO:0043125; GO:0043539; GO:0043548; GO:0043551; GO:0043559; GO:0043560; GO:0045671; GO:0045944; GO:0046326; GO:0046626; GO:0046854; GO:0046935; GO:0046982; GO:0048009; GO:0048471; GO:0050821; GO:0051491; GO:0051497; GO:0060396; GO:0097529; GO:0120183; GO:1900103; GO:1903078; GO:1990578 825 XM_044318987.1 224 178 177 419 409 Q8C8N2 0 Protein SCAI (Suppressor of cancer cell invasion protein) Mus musculus (Mouse) negative regulation of cell migration [GO:0030336]; negative regulation of Rho protein signal transduction [GO:0035024] GO:0003714; GO:0005634; GO:0005654; GO:0005737; GO:0030336; GO:0031965; GO:0035024 826 XM_044328282.1 274 125 77 51 49 NA NA NA NA NA NA 827 XM_044327947.1 22 18 26 54 54 NA NA NA NA NA NA 828 XR_006397057.1 0 19 3 8 2 NA NA NA NA NA NA 829 XR_006398204.1 427 140 296 207 394 Q5DU56 1.77e-25 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 830 XR_006398204.1 427 140 296 207 394 Q5DU56 1.77e-25 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 831 XR_006398204.1 427 140 296 207 394 Q5DU56 1.77e-23 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 832 XR_006398204.1 427 140 296 207 394 Q5DU56 1.77e-23 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 833 XR_006398204.1 427 140 296 207 394 Q5DU56 2.94e-23 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 834 XR_006398204.1 427 140 296 207 394 Q5DU56 2.94e-23 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 835 XR_006398204.1 427 140 296 207 394 Q5DU56 5.57e-21 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 836 XR_006398204.1 427 140 296 207 394 Q5DU56 9.98e-21 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 837 XR_006398204.1 427 140 296 207 394 Q5DU56 9.98e-21 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 838 XM_044326699.1 12 52 19 16 27 NA NA NA NA NA NA 839 XM_044314358.1 737 48 920 129 3674 P35061 7.93e-53 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 840 XM_029336321.2 0 17 156 30 26 NA NA NA NA NA NA 841 XM_044325417.1 650 202 461 1012 1836 Q9DBN1 4.27e-30 Stimulated by retinoic acid gene 6 protein-like (STRA6-like protein) (Retinol-binding protein 4 receptor 2) (RBP4 receptor 2) Mus musculus (Mouse) establishment of localization in cell [GO:0051649]; retinol transport [GO:0034633]; vitamin A import into cell [GO:0071939] GO:0005886; GO:0034633; GO:0051649; GO:0071939 842 XM_029336953.2 0 0 3 0 6 NA NA NA NA NA NA 843 XM_029344141.2 25 0 8 35 20 Q9CZR2 5.83e-111 N-acetylated-alpha-linked acidic dipeptidase 2 (EC 3.4.17.21) (Glutamate carboxypeptidase III) (GCPIII) (N-acetylaspartylglutamate peptidase II) (NAAG-peptidase II) (N-acetylated-alpha-linked acidic dipeptidase II) (NAALADase II) Mus musculus (Mouse) neurotransmitter catabolic process [GO:0042135]; proteolysis [GO:0006508] GO:0004180; GO:0004181; GO:0005886; GO:0006508; GO:0008233; GO:0016020; GO:0016805; GO:0042135; GO:0046872; GO:0050129 844 XM_044318182.1 1874 6440 1160 896 621 NA NA NA NA NA NA 845 XM_029340341.2 43 62 90 152 137 NA NA NA NA NA NA 846 XR_006393307.1 0 22 17 24 16 NA NA NA NA NA NA 847 XM_044322696.1 306 146 150 233 468 Q23915 2.34e-27 Probable serine/threonine-protein kinase kinX (EC 2.7.11.1) Dictyostelium discoideum (Social amoeba) protein phosphorylation [GO:0006468]; signal transduction [GO:0007165] GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0006468; GO:0007165; GO:0106310 848 XM_044322696.1 306 146 150 233 468 Q23915 3.75e-26 Probable serine/threonine-protein kinase kinX (EC 2.7.11.1) Dictyostelium discoideum (Social amoeba) protein phosphorylation [GO:0006468]; signal transduction [GO:0007165] GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0006468; GO:0007165; GO:0106310 849 XM_044310637.1 2 0 0 0 12 NA NA NA NA NA NA 850 XR_003827237.2 6 5 0 1 3 NA NA NA NA NA NA 851 XM_029346285.2 182 139 243 177 182 Q8BJQ9 1.56e-122 Chondroitin sulfate N-acetylgalactosaminyltransferase 1 (CsGalNAcT-1) (EC 2.4.1.174) (Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 1) (Beta4GalNAcT-1) Mus musculus (Mouse) cartilage development [GO:0051216]; chondroitin sulfate biosynthetic process [GO:0030206]; chondroitin sulfate metabolic process [GO:0030204]; chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0050653]; endochondral ossification [GO:0001958]; extracellular matrix organization [GO:0030198]; UDP-glucuronate metabolic process [GO:0046398]; UDP-N-acetylgalactosamine metabolic process [GO:0019276] GO:0001958; GO:0005794; GO:0008376; GO:0008955; GO:0015020; GO:0019276; GO:0030198; GO:0030204; GO:0030206; GO:0032580; GO:0046398; GO:0046872; GO:0047237; GO:0047238; GO:0050653; GO:0051216 852 XM_044319859.1 597 332 317 450 375 O00268 1.73e-50 Transcription initiation factor TFIID subunit 4 (RNA polymerase II TBP-associated factor subunit C) (TBP-associated factor 4) (Transcription initiation factor TFIID 130 kDa subunit) (TAF(II)130) (TAFII-130) (TAFII130) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) Homo sapiens (Human) DNA-templated transcription initiation [GO:0006352]; histone H3 acetylation [GO:0043966]; monoubiquitinated histone deubiquitination [GO:0035521]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; mRNA transcription by RNA polymerase II [GO:0042789]; ovarian follicle development [GO:0001541]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription by RNA polymerase II [GO:0006366]; transcription initiation at RNA polymerase II promoter [GO:0006367] GO:0000785; GO:0001541; GO:0001673; GO:0003677; GO:0005634; GO:0005654; GO:0005669; GO:0005829; GO:0006282; GO:0006352; GO:0006357; GO:0006366; GO:0006367; GO:0006468; GO:0017162; GO:0032991; GO:0033276; GO:0035521; GO:0035522; GO:0042789; GO:0043966; GO:0045893; GO:0046982; GO:0051123; GO:0060261; GO:0071339 853 XM_044314241.1 0 30 0 207 26 NA NA NA NA NA NA 854 XM_044320003.1 0 126 0 166 66 P61765 0 Syntaxin-binding protein 1 (N-Sec1) (Protein unc-18 homolog 1) (Unc18-1) (Protein unc-18 homolog A) (Unc-18A) (p67) (rbSec1) Rattus norvegicus (Rat) axon target recognition [GO:0007412]; cellular response to type II interferon [GO:0071346]; developmental process involved in reproduction [GO:0003006]; establishment of localization in cell [GO:0051649]; exocytosis [GO:0006887]; intracellular protein transport [GO:0006886]; long-term synaptic depression [GO:0060292]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of SNARE complex assembly [GO:0035544]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; neuromuscular synaptic transmission [GO:0007274]; neuron apoptotic process [GO:0051402]; neurotransmitter secretion [GO:0007269]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of exocytosis [GO:0045921]; positive regulation of glutamate secretion, neurotransmission [GO:1903296]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of vesicle docking [GO:0106022]; presynaptic dense core vesicle exocytosis [GO:0099525]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; regulation of acrosomal vesicle exocytosis [GO:2000367]; regulation of synaptic vesicle priming [GO:0010807]; regulation of vesicle fusion [GO:0031338]; response to estradiol [GO:0032355]; SNARE complex assembly [GO:0035493]; synaptic vesicle maturation [GO:0016188]; synaptic vesicle priming [GO:0016082]; vesicle docking involved in exocytosis [GO:0006904]; vesicle-mediated transport [GO:0016192] GO:0000149; GO:0002576; GO:0003006; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0006886; GO:0006887; GO:0006904; GO:0007269; GO:0007274; GO:0007412; GO:0010807; GO:0016082; GO:0016188; GO:0016192; GO:0017075; GO:0019901; GO:0019904; GO:0019905; GO:0030141; GO:0030424; GO:0031091; GO:0031333; GO:0031338; GO:0032229; GO:0032355; GO:0032991; GO:0035493; GO:0035544; GO:0042802; GO:0043195; GO:0043274; GO:0043306; GO:0043524; GO:0045335; GO:0045921; GO:0045956; GO:0047485; GO:0048471; GO:0048787; GO:0050821; GO:0051402; GO:0051649; GO:0060090; GO:0060292; GO:0070527; GO:0071346; GO:0072659; GO:0098688; GO:0098793; GO:0098794; GO:0098831; GO:0098888; GO:0098978; GO:0099523; GO:0099525; GO:0106022; GO:1903296; GO:2000367 855 XM_029350101.2 2912 2155 1200 2037 1538 Q6P3K3 1.06e-96 F-box only protein 9 Danio rerio (Zebrafish) (Brachydanio rerio) protein ubiquitination [GO:0016567]; regulation of TOR signaling [GO:0032006]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0005737; GO:0016567; GO:0019005; GO:0031146; GO:0032006 856 XM_044311239.1 0 0 0 0 11 NA NA NA NA NA NA 857 XM_044314071.1 445 301 248 340 354 F6QEU4 1.01e-34 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 858 XM_044314071.1 445 301 248 340 354 F6QEU4 3.98e-21 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 859 XM_029339717.2 0 0 0 0 35 NA NA NA NA NA NA 860 XM_029353894.2 19 1 11 5 20 NA NA NA NA NA NA 861 XM_029323596.2 0 0 123 0 13 Q8WVC0 1.94e-41 RNA polymerase-associated protein LEO1 (Replicative senescence down-regulated leo1-like protein) Homo sapiens (Human) endodermal cell fate commitment [GO:0001711]; histone H2B ubiquitination [GO:0033523]; histone monoubiquitination [GO:0010390]; mRNA polyadenylation [GO:0006378]; negative regulation of myeloid cell differentiation [GO:0045638]; positive regulation of mRNA 3'-end processing [GO:0031442]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; stem cell population maintenance [GO:0019827]; transcription elongation by RNA polymerase II promoter [GO:0006368]; Wnt signaling pathway [GO:0016055] GO:0001650; GO:0001711; GO:0005634; GO:0005654; GO:0005813; GO:0006368; GO:0006378; GO:0010390; GO:0016055; GO:0016593; GO:0019827; GO:0031442; GO:0032968; GO:0033523; GO:0045638; GO:1990269 862 XM_044320008.1 11 12 10 3 16 Q5HZQ8 1.66e-64 Ethylmalonyl-CoA decarboxylase (EC 4.1.1.94) (Enoyl-CoA hydratase domain-containing protein 1) (Methylmalonyl-CoA decarboxylase) (MMCD) Xenopus laevis (African clawed frog) NA GO:0004492; GO:0005829; GO:0016831 863 XM_044317851.1 522 665 316 784 311 NA NA NA NA NA NA 864 XM_029337886.2 260 19 87 260 224 NA NA NA NA NA NA 865 XM_044321372.1 20 0 6 20 20 NA NA NA NA NA NA 866 XM_044308179.1 303 137 149 171 257 Q8BNU0 4.45e-108 Armadillo repeat-containing protein 6 Mus musculus (Mouse) hematopoietic progenitor cell differentiation [GO:0002244] GO:0002244; GO:0005829 867 XM_029330168.2 0 0 4 5 13 NA NA NA NA NA NA 868 XM_044319433.1 0 27 11 45 0 NA NA NA NA NA NA 869 XR_003828434.2 175 106 125 206 434 NA NA NA NA NA NA 870 XM_044323586.1 0 6 4 0 1 NA NA NA NA NA NA 871 XM_044319372.1 120 125 80 123 110 P0CI65 7.14e-49 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 872 XM_044319372.1 120 125 80 123 110 P0CI65 1.03e-48 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 873 XM_044319372.1 120 125 80 123 110 P0CI65 5.15e-43 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 874 XM_044319372.1 120 125 80 123 110 P0CI65 8.47e-42 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 875 XM_044319372.1 120 125 80 123 110 P0CI65 1.72e-41 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 876 XM_044319372.1 120 125 80 123 110 P0CI65 1.28e-38 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 877 XM_044319372.1 120 125 80 123 110 P0CI65 2.62e-36 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 878 XM_044319372.1 120 125 80 123 110 P0CI65 6.31e-21 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 879 XM_044321438.1 0 0 6 0 0 Q91ZI0 5.85e-65 Cadherin EGF LAG seven-pass G-type receptor 3 Mus musculus (Mouse) axonal fasciculation [GO:0007413]; cell-cell adhesion [GO:0098609]; cilium assembly [GO:0060271]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; planar cell polarity pathway involved in axon guidance [GO:1904938]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] GO:0001932; GO:0004930; GO:0005509; GO:0005886; GO:0007156; GO:0007413; GO:0032880; GO:0036514; GO:0036515; GO:0060271; GO:0097475; GO:0098609; GO:1904938 880 XM_044321438.1 0 0 6 0 0 Q91ZI0 4.18e-45 Cadherin EGF LAG seven-pass G-type receptor 3 Mus musculus (Mouse) axonal fasciculation [GO:0007413]; cell-cell adhesion [GO:0098609]; cilium assembly [GO:0060271]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; planar cell polarity pathway involved in axon guidance [GO:1904938]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] GO:0001932; GO:0004930; GO:0005509; GO:0005886; GO:0007156; GO:0007413; GO:0032880; GO:0036514; GO:0036515; GO:0060271; GO:0097475; GO:0098609; GO:1904938 881 XM_044321438.1 0 0 6 0 0 Q91ZI0 1.03e-37 Cadherin EGF LAG seven-pass G-type receptor 3 Mus musculus (Mouse) axonal fasciculation [GO:0007413]; cell-cell adhesion [GO:0098609]; cilium assembly [GO:0060271]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; planar cell polarity pathway involved in axon guidance [GO:1904938]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] GO:0001932; GO:0004930; GO:0005509; GO:0005886; GO:0007156; GO:0007413; GO:0032880; GO:0036514; GO:0036515; GO:0060271; GO:0097475; GO:0098609; GO:1904938 882 XM_044321438.1 0 0 6 0 0 Q91ZI0 6.75e-33 Cadherin EGF LAG seven-pass G-type receptor 3 Mus musculus (Mouse) axonal fasciculation [GO:0007413]; cell-cell adhesion [GO:0098609]; cilium assembly [GO:0060271]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; planar cell polarity pathway involved in axon guidance [GO:1904938]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] GO:0001932; GO:0004930; GO:0005509; GO:0005886; GO:0007156; GO:0007413; GO:0032880; GO:0036514; GO:0036515; GO:0060271; GO:0097475; GO:0098609; GO:1904938 883 XR_006393374.1 29 33 41 33 21 NA NA NA NA NA NA 884 XM_044324238.1 157 0 123 21 0 NA NA NA NA NA NA 885 XM_044324573.1 1514 1495 811 2222 1055 NA NA NA NA NA NA 886 XM_029346974.2 141 330 178 273 178 Q6R520 5.64e-50 Calmodulin (CaM) Oreochromis mossambicus (Mozambique tilapia) (Tilapia mossambica) NA GO:0005509 887 XM_044328665.1 474 148 242 114 205 Q6V0K7 7.26e-50 Oncoprotein-induced transcript 3 protein (Liver-specific zona pellucida domain-containing protein) Rattus norvegicus (Rat) urate homeostasis [GO:1903118] GO:0005201; GO:0005509; GO:0005615; GO:0005635; GO:0009986; GO:1903118 888 XM_044316044.1 15 0 2 12 143 NA NA NA NA NA NA 889 XM_044315332.1 0 6 5 4 0 NA NA NA NA NA NA 890 XM_044313665.1 3 7 35 22 19 C3VPR6 8.15e-26 Protein NLRC5 Mus musculus (Mouse) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of type II interferon-mediated signaling pathway [GO:0060335]; regulation of kinase activity [GO:0043549]; response to bacterium [GO:0009617] GO:0000978; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0009617; GO:0032088; GO:0035556; GO:0043549; GO:0045087; GO:0045345; GO:0045944; GO:0051607; GO:0060335; GO:0060339; GO:0060340 891 XM_029330863.2 0 0 13 14 0 NA NA NA NA NA NA 892 XM_044324818.1 274 252 225 370 318 NA NA NA NA NA NA 893 XM_029329969.2 0 41 0 54 81 Q9NQX0 3.14e-76 Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.361) (PR domain zinc finger protein 6) (PR domain-containing protein 6) Homo sapiens (Human) chromatin organization [GO:0006325]; histone methylation [GO:0016571]; negative regulation of smooth muscle cell differentiation [GO:0051151]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of gene expression [GO:0010468] GO:0000122; GO:0005634; GO:0006325; GO:0010468; GO:0016571; GO:0022008; GO:0042802; GO:0046872; GO:0051151; GO:0140944 894 XM_044319500.1 0 0 49 81 107 NA NA NA NA NA NA 895 XR_003828247.1 1291 1908 637 999 946 NA NA NA NA NA NA 896 XR_006391408.1 0 0 0 12 0 NA NA NA NA NA NA 897 XM_029353918.2 1 15 6 20 68 NA NA NA NA NA NA 898 XM_044310563.1 20 0 2 19 1 NA NA NA NA NA NA 899 XM_044311758.1 1 39 0 2 44 NA NA NA NA NA NA 900 XM_029342293.2 11 0 0 2 11 NA NA NA NA NA NA 901 XM_044315210.1 6 0 10 7 0 NA NA NA NA NA NA 902 XR_006395564.1 10 0 3 0 2 NA NA NA NA NA NA 903 XR_006394394.1 3 0 8 20 1 NA NA NA NA NA NA 904 XM_044322774.1 63 118 0 0 0 Q8IYE1 7.42e-54 Coiled-coil domain-containing protein 13 Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; cytoplasmic microtubule organization [GO:0031122]; non-motile cilium assembly [GO:1905515] GO:0005654; GO:0005813; GO:0005829; GO:0006974; GO:0031122; GO:0034451; GO:0042995; GO:1905515 905 XM_044322774.1 63 118 0 0 0 Q8IYE1 4.26e-25 Coiled-coil domain-containing protein 13 Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; cytoplasmic microtubule organization [GO:0031122]; non-motile cilium assembly [GO:1905515] GO:0005654; GO:0005813; GO:0005829; GO:0006974; GO:0031122; GO:0034451; GO:0042995; GO:1905515 906 XM_029340677.2 0 0 0 4 13 NA NA NA NA NA NA 907 XM_044328258.1 100 73 34 92 78 Q0VFD8 8.17e-29 Biogenesis of lysosome-related organelles complex 1 subunit 1 (BLOC-1 subunit 1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) aerobic respiration [GO:0009060]; anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; lysosome localization [GO:0032418]; neuron projection development [GO:0031175]; peptidyl-lysine acetylation [GO:0018394] GO:0005758; GO:0005759; GO:0005765; GO:0005829; GO:0008089; GO:0009060; GO:0018394; GO:0031083; GO:0031175; GO:0032418; GO:0048490; GO:0099078; GO:1904115 908 XM_029339348.2 2179 3218 1720 3303 3179 Q98SN7 1.05e-89 Protein Wnt-2b Gallus gallus (Chicken) camera-type eye photoreceptor cell differentiation [GO:0060219]; canonical Wnt signaling pathway [GO:0060070]; cell population proliferation [GO:0008283]; cornea development in camera-type eye [GO:0061303]; embryonic camera-type eye formation [GO:0060900]; embryonic forelimb morphogenesis [GO:0035115]; iris morphogenesis [GO:0061072]; lens development in camera-type eye [GO:0002088]; limb development [GO:0060173]; morphogenesis of an epithelial sheet [GO:0002011]; negative regulation of glial cell differentiation [GO:0045686]; negative regulation of neuron differentiation [GO:0045665]; neural retina development [GO:0003407]; neuron differentiation [GO:0030182]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of fibroblast growth factor receptor signaling pathway [GO:0045743]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of fibroblast growth factor production [GO:0090270]; retina layer formation [GO:0010842]; Wnt signaling pathway [GO:0016055] GO:0002011; GO:0002088; GO:0003407; GO:0005109; GO:0005576; GO:0008283; GO:0010842; GO:0016055; GO:0030182; GO:0035115; GO:0045665; GO:0045686; GO:0045743; GO:0060070; GO:0060173; GO:0060219; GO:0060828; GO:0060900; GO:0061072; GO:0061303; GO:0090270; GO:0090271 909 XM_044316578.1 7891 6299 4643 9921 3314 Q7T2C4 5.19e-131 NA NA NA NA 910 XM_029355760.2 36 32 73 207 135 Q8N539 8.5e-68 Fibrinogen C domain-containing protein 1 Homo sapiens (Human) cell adhesion [GO:0007155] GO:0005102; GO:0005615; GO:0007155; GO:0008061; GO:0016020; GO:0046872; GO:0062023 911 XM_044317107.1 0 1 0 1 8 NA NA NA NA NA NA 912 XM_029329337.2 11 15 12 17 7 NA NA NA NA NA NA 913 XM_044325023.1 55 33 55 55 226 NA NA NA NA NA NA 914 XR_006393143.1 755 997 1008 163 1126 NA NA NA NA NA NA 915 XM_029352385.2 9407 7236 4009 7741 3018 Q5RF87 4.69e-146 Selenide, water dikinase 1 (EC 2.7.9.3) (Selenium donor protein 1) (Selenophosphate synthase 1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) phosphorylation [GO:0016310] GO:0004756; GO:0005524; GO:0005886; GO:0016310; GO:0031965; GO:0042803; GO:0046872; GO:0046982 916 XM_044323855.1 190 141 116 234 81 NA NA NA NA NA NA 917 XM_029346966.2 9 32 18 34 9 NA NA NA NA NA NA 918 XM_029348212.2 343 462 335 334 379 O09173 0 Homogentisate 1,2-dioxygenase (EC 1.13.11.5) (Homogentisate oxygenase) (Homogentisic acid oxidase) (Homogentisicase) Mus musculus (Mouse) amino acid metabolic process [GO:0006520]; L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572] GO:0004411; GO:0006520; GO:0006559; GO:0006572; GO:0042802; GO:0046872 919 XM_044310100.1 0 0 0 815 0 NA NA NA NA NA NA 920 XM_044313071.1 18 22 7 20 3 Q80XJ3 3.25e-48 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 921 XM_044313071.1 18 22 7 20 3 Q80XJ3 1.78e-45 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 922 XM_044313071.1 18 22 7 20 3 Q80XJ3 2.77e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 923 XM_044313071.1 18 22 7 20 3 Q80XJ3 4.44e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 924 XM_044313071.1 18 22 7 20 3 Q80XJ3 7.7e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 925 XM_044313071.1 18 22 7 20 3 Q80XJ3 2.49e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 926 XM_044313071.1 18 22 7 20 3 Q80XJ3 2.56e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 927 XM_044313071.1 18 22 7 20 3 Q80XJ3 4.37e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 928 XM_044313071.1 18 22 7 20 3 Q80XJ3 6.22e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 929 XM_044313071.1 18 22 7 20 3 Q80XJ3 8.67e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 930 XM_044313071.1 18 22 7 20 3 Q80XJ3 5e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 931 XR_006397426.1 193 422 41 114 55 NA NA NA NA NA NA 932 XM_029333550.2 165 169 105 80 223 Q9Z2L6 1.63e-38 Multiple inositol polyphosphate phosphatase 1 (EC 3.1.3.62) (2,3-bisphosphoglycerate 3-phosphatase) (2,3-BPG phosphatase) (EC 3.1.3.80) (Inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase) (Ins(1,3,4,5)P(4) 3-phosphatase) Mus musculus (Mouse) NA GO:0003993; GO:0005788; GO:0005886; GO:0030351; GO:0030352; GO:0034417; GO:0052745; GO:0052826 933 XM_044320119.1 6 0 2 0 45 NA NA NA NA NA NA 934 XM_044315706.1 577 606 230 815 569 Q0P5F0 2.5e-40 Lysosomal acid phosphatase (LAP) (EC 3.1.3.2) Bos taurus (Bovine) dephosphorylation [GO:0016311]; lysosome organization [GO:0007040] GO:0003993; GO:0005764; GO:0005765; GO:0007040; GO:0016311; GO:0016791; GO:0043202 935 XM_044307333.1 883 446 490 656 1026 Q8CE96 5.82e-97 tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 (mRNA methyladenosine-N(1)-methyltransferase non-catalytic subunit TRM6) (tRNA(m1A58)-methyltransferase subunit TRM6) (tRNA(m1A58)MTase subunit TRM6) Mus musculus (Mouse) mRNA methylation [GO:0080009]; tRNA methylation [GO:0030488] GO:0005634; GO:0030488; GO:0031515; GO:0080009 936 XM_044328684.1 0 10 7 12 0 P16065 0 Speract receptor (EC 4.6.1.2) (Guanylate cyclase) Strongylocentrotus purpuratus (Purple sea urchin) cGMP biosynthetic process [GO:0006182]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]; receptor guanylyl cyclase signaling pathway [GO:0007168]; signal transduction [GO:0007165] GO:0001653; GO:0004383; GO:0004672; GO:0005524; GO:0005525; GO:0005886; GO:0006182; GO:0006468; GO:0007165; GO:0007168; GO:0035556 937 XM_044314412.1 296 192 271 450 836 NA NA NA NA NA NA 938 XM_044322032.1 291 123 186 228 259 Q5RDZ2 1.19e-76 Lambda-crystallin homolog (EC 1.1.1.45) (L-gulonate 3-dehydrogenase) (Gul3DH) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) fatty acid metabolic process [GO:0006631]; glucuronate catabolic process to xylulose 5-phosphate [GO:0019640] GO:0005829; GO:0006631; GO:0019640; GO:0042803; GO:0050104; GO:0070403 939 XM_044316248.1 76 59 34 31 48 NA NA NA NA NA NA 940 XM_029327526.2 114 110 73 0 27 NA NA NA NA NA NA 941 XM_044326336.1 0 19 0 26 26 NA NA NA NA NA NA 942 XM_044321736.1 306 169 271 278 395 Q7Z7G8 1.73e-105 Intermembrane lipid transfer protein VPS13B (Cohen syndrome protein 1) (Vacuolar protein sorting-associated protein 13B) Homo sapiens (Human) acrosome assembly [GO:0001675]; adipose tissue development [GO:0060612]; central nervous system development [GO:0007417]; Golgi organization [GO:0007030]; Golgi reassembly [GO:0090168]; lipid transport [GO:0006869]; maintenance of lens transparency [GO:0036438]; nervous system development [GO:0007399]; neuron projection development [GO:0031175]; slow endocytic recycling [GO:0032458]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0001675; GO:0002080; GO:0005765; GO:0006869; GO:0007030; GO:0007399; GO:0007417; GO:0016192; GO:0031175; GO:0031901; GO:0032266; GO:0032458; GO:0032588; GO:0033106; GO:0033116; GO:0036438; GO:0055038; GO:0060612; GO:0090168 943 XM_044321736.1 306 169 271 278 395 Q7Z7G8 2.16e-88 Intermembrane lipid transfer protein VPS13B (Cohen syndrome protein 1) (Vacuolar protein sorting-associated protein 13B) Homo sapiens (Human) acrosome assembly [GO:0001675]; adipose tissue development [GO:0060612]; central nervous system development [GO:0007417]; Golgi organization [GO:0007030]; Golgi reassembly [GO:0090168]; lipid transport [GO:0006869]; maintenance of lens transparency [GO:0036438]; nervous system development [GO:0007399]; neuron projection development [GO:0031175]; slow endocytic recycling [GO:0032458]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0001675; GO:0002080; GO:0005765; GO:0006869; GO:0007030; GO:0007399; GO:0007417; GO:0016192; GO:0031175; GO:0031901; GO:0032266; GO:0032458; GO:0032588; GO:0033106; GO:0033116; GO:0036438; GO:0055038; GO:0060612; GO:0090168 944 XM_044321736.1 306 169 271 278 395 Q7Z7G8 6.62e-80 Intermembrane lipid transfer protein VPS13B (Cohen syndrome protein 1) (Vacuolar protein sorting-associated protein 13B) Homo sapiens (Human) acrosome assembly [GO:0001675]; adipose tissue development [GO:0060612]; central nervous system development [GO:0007417]; Golgi organization [GO:0007030]; Golgi reassembly [GO:0090168]; lipid transport [GO:0006869]; maintenance of lens transparency [GO:0036438]; nervous system development [GO:0007399]; neuron projection development [GO:0031175]; slow endocytic recycling [GO:0032458]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0001675; GO:0002080; GO:0005765; GO:0006869; GO:0007030; GO:0007399; GO:0007417; GO:0016192; GO:0031175; GO:0031901; GO:0032266; GO:0032458; GO:0032588; GO:0033106; GO:0033116; GO:0036438; GO:0055038; GO:0060612; GO:0090168 945 XM_029330633.2 1544 1180 896 1404 1185 Q0V9R4 0 Coiled-coil domain-containing protein 39 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) axonemal dynein complex assembly [GO:0070286]; cilium-dependent cell motility [GO:0060285]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; inner dynein arm assembly [GO:0036159] GO:0005576; GO:0005930; GO:0036159; GO:0060285; GO:0060287; GO:0070286 946 XM_029342837.2 1131 536 1003 1352 1617 P81439 2.3e-33 Equistatin (EI) (Cysteine proteinase inhibitor) Actinia equina (Beadlet anemone) negative regulation of peptidase activity [GO:0010466] GO:0004869; GO:0005576; GO:0010466 947 XM_029342837.2 1131 536 1003 1352 1617 P81439 1.02e-32 Equistatin (EI) (Cysteine proteinase inhibitor) Actinia equina (Beadlet anemone) negative regulation of peptidase activity [GO:0010466] GO:0004869; GO:0005576; GO:0010466 948 XM_029342837.2 1131 536 1003 1352 1617 P81439 2.04e-32 Equistatin (EI) (Cysteine proteinase inhibitor) Actinia equina (Beadlet anemone) negative regulation of peptidase activity [GO:0010466] GO:0004869; GO:0005576; GO:0010466 949 XM_029342837.2 1131 536 1003 1352 1617 P81439 2.79e-31 Equistatin (EI) (Cysteine proteinase inhibitor) Actinia equina (Beadlet anemone) negative regulation of peptidase activity [GO:0010466] GO:0004869; GO:0005576; GO:0010466 950 XM_029342837.2 1131 536 1003 1352 1617 P81439 3.46e-30 Equistatin (EI) (Cysteine proteinase inhibitor) Actinia equina (Beadlet anemone) negative regulation of peptidase activity [GO:0010466] GO:0004869; GO:0005576; GO:0010466 951 XM_029342837.2 1131 536 1003 1352 1617 P81439 1.08e-28 Equistatin (EI) (Cysteine proteinase inhibitor) Actinia equina (Beadlet anemone) negative regulation of peptidase activity [GO:0010466] GO:0004869; GO:0005576; GO:0010466 952 XM_029342837.2 1131 536 1003 1352 1617 P81439 3.58e-28 Equistatin (EI) (Cysteine proteinase inhibitor) Actinia equina (Beadlet anemone) negative regulation of peptidase activity [GO:0010466] GO:0004869; GO:0005576; GO:0010466 953 XM_029342837.2 1131 536 1003 1352 1617 P81439 8.57e-28 Equistatin (EI) (Cysteine proteinase inhibitor) Actinia equina (Beadlet anemone) negative regulation of peptidase activity [GO:0010466] GO:0004869; GO:0005576; GO:0010466 954 XM_029342837.2 1131 536 1003 1352 1617 P81439 2.07e-26 Equistatin (EI) (Cysteine proteinase inhibitor) Actinia equina (Beadlet anemone) negative regulation of peptidase activity [GO:0010466] GO:0004869; GO:0005576; GO:0010466 955 XM_029342837.2 1131 536 1003 1352 1617 P81439 2.87e-22 Equistatin (EI) (Cysteine proteinase inhibitor) Actinia equina (Beadlet anemone) negative regulation of peptidase activity [GO:0010466] GO:0004869; GO:0005576; GO:0010466 956 XM_029342837.2 1131 536 1003 1352 1617 P81439 2.52e-21 Equistatin (EI) (Cysteine proteinase inhibitor) Actinia equina (Beadlet anemone) negative regulation of peptidase activity [GO:0010466] GO:0004869; GO:0005576; GO:0010466 957 XM_029342837.2 1131 536 1003 1352 1617 P81439 7.26e-21 Equistatin (EI) (Cysteine proteinase inhibitor) Actinia equina (Beadlet anemone) negative regulation of peptidase activity [GO:0010466] GO:0004869; GO:0005576; GO:0010466 958 XR_006393481.1 20 0 7 14 30 Q96DM1 4.64e-47 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 959 XM_029333273.2 0 119 162 238 1220 NA NA NA NA NA NA 960 XR_003827355.2 98 111 199 114 81 NA NA NA NA NA NA 961 XM_029355639.2 11 4 5 2 11 NA NA NA NA NA NA 962 XM_044324258.1 194 37 38 232 174 P07949 7.41e-76 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; axon guidance [GO:0007411]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; lymphocyte migration into lymphoid organs [GO:0097021]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; posterior midgut development [GO:0007497]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006468; GO:0006919; GO:0007156; GO:0007158; GO:0007165; GO:0007169; GO:0007411; GO:0007497; GO:0009410; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0038023; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0097021; GO:0098797; GO:2001241 963 XM_029330700.2 796 798 729 878 1070 Q6P1X6 2.57e-52 UPF0598 protein C8orf82 Homo sapiens (Human) NA NA 964 XM_044311018.1 590 1057 392 701 783 Q9UJG1 6.46e-48 Motile sperm domain-containing protein 1 Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000122; GO:0000139; GO:0005634; GO:0005737; GO:0005789; GO:0030154; GO:0045944; GO:0048471 965 XR_006395127.1 0 3 3 16 16 NA NA NA NA NA NA 966 XM_029335899.2 2567 2432 1620 2572 2781 Q8BKX6 0 Serine/threonine-protein kinase SMG1 (SMG-1) (EC 2.7.11.1) (Lambda/iota protein kinase C-interacting protein) (Lambda-interacting protein) (Nonsense mediated mRNA decay-associated PI3K-related kinase SMG1) Mus musculus (Mouse) DNA repair [GO:0006281]; negative regulation of macroautophagy [GO:0016242]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine phosphorylation [GO:0018105]; phosphatidylinositol phosphate biosynthetic process [GO:0046854]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of response to DNA damage stimulus [GO:2001020]; regulation of telomere maintenance [GO:0032204]; TOR signaling [GO:0031929] GO:0000184; GO:0004674; GO:0004697; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0006281; GO:0006468; GO:0016242; GO:0018105; GO:0031929; GO:0031931; GO:0031932; GO:0032204; GO:0033391; GO:0042162; GO:0046777; GO:0046854; GO:0046872; GO:0106310; GO:2001020 967 XM_044308064.1 213 15 15 81 306 NA NA NA NA NA NA 968 XM_044311645.1 0 11 0 0 0 Q90610 6.61e-32 Neogenin Gallus gallus (Chicken) cell adhesion [GO:0007155] GO:0005886; GO:0007155 969 XR_006391983.1 219 152 83 178 389 NA NA NA NA NA NA 970 XM_029326820.2 1 0 0 12 18 NA NA NA NA NA NA 971 XM_029336515.2 314 92 0 328 104 NA NA NA NA NA NA 972 XM_044322087.1 357 237 133 679 400 Q8CBF3 0 Ephrin type-B receptor 1 (EC 2.7.10.1) Mus musculus (Mouse) angiogenesis [GO:0001525]; axon guidance [GO:0007411]; camera-type eye morphogenesis [GO:0048593]; cell chemotaxis [GO:0060326]; cell-substrate adhesion [GO:0031589]; central nervous system projection neuron axonogenesis [GO:0021952]; cranial nerve development [GO:0021545]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; ephrin receptor signaling pathway [GO:0048013]; establishment of cell polarity [GO:0030010]; hindbrain tangential cell migration [GO:0021934]; immunological synapse formation [GO:0001771]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of satellite cell differentiation [GO:1902725]; negative regulation of skeletal muscle satellite cell proliferation [GO:1902723]; neural precursor cell proliferation [GO:0061351]; neurogenesis [GO:0022008]; optic nerve morphogenesis [GO:0021631]; positive regulation of kinase activity [GO:0033674]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of neuron death [GO:1901214]; retinal ganglion cell axon guidance [GO:0031290]; skeletal muscle satellite cell activation [GO:0014719]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0001525; GO:0001771; GO:0004713; GO:0004714; GO:0005005; GO:0005524; GO:0005737; GO:0005783; GO:0005829; GO:0005886; GO:0007169; GO:0007411; GO:0008046; GO:0014719; GO:0016020; GO:0021545; GO:0021631; GO:0021934; GO:0021952; GO:0022008; GO:0030010; GO:0030424; GO:0030425; GO:0031290; GO:0031589; GO:0031901; GO:0032433; GO:0033674; GO:0043005; GO:0043235; GO:0044877; GO:0045121; GO:0046328; GO:0046777; GO:0048013; GO:0048593; GO:0050804; GO:0050965; GO:0051965; GO:0060326; GO:0060996; GO:0060997; GO:0061351; GO:0070372; GO:0098978; GO:1901214; GO:1902723; GO:1902725 973 XM_029328479.2 1763 3514 659 2983 1489 NA NA NA NA NA NA 974 XM_044318011.1 0 57 0 7 0 NA NA NA NA NA NA 975 XR_006393257.1 113 55 123 183 321 NA NA NA NA NA NA 976 XR_006395197.1 59 75 27 75 63 NA NA NA NA NA NA 977 XM_044326232.1 9 11 8 24 48 NA NA NA NA NA NA 978 XM_044320767.1 0 3 0 4 9 NA NA NA NA NA NA 979 XM_029343504.2 173 77 45 89 85 Q8CBH5 1.97e-34 Major facilitator superfamily domain-containing protein 6 (Macrophage MHC class I receptor 2) Mus musculus (Mouse) adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590] GO:0002250; GO:0005886; GO:0016020; GO:0032393; GO:0042288; GO:0042590 980 XR_006395304.1 5 3 1 0 10 NA NA NA NA NA NA 981 XM_029343974.2 1 255 92 0 119 B9EJ86 0 Oxysterol-binding protein-related protein 8 (ORP-8) (OSBP-related protein 8) Mus musculus (Mouse) activation of protein kinase B activity [GO:0032148]; fat cell differentiation [GO:0045444]; negative regulation of cell migration [GO:0030336]; negative regulation of sequestering of triglyceride [GO:0010891]; phospholipid transport [GO:0015914]; positive regulation of glucose import [GO:0046326]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of protein kinase B signaling [GO:0051897]; protein localization to nuclear pore [GO:0090204] GO:0001786; GO:0005783; GO:0005789; GO:0005829; GO:0010891; GO:0015248; GO:0015485; GO:0015914; GO:0016020; GO:0030336; GO:0031965; GO:0032148; GO:0032541; GO:0032934; GO:0043231; GO:0045444; GO:0046326; GO:0046628; GO:0051897; GO:0070273; GO:0090204; GO:0140343 982 XM_044324812.1 940 877 638 415 620 NA NA NA NA NA NA 983 XM_044329291.1 181 205 184 309 396 NA NA NA NA NA NA 984 XM_029345193.2 0 0 0 0 20 Q9UKJ5 2.09e-52 Cysteine-rich hydrophobic domain-containing protein 2 (BrX-like translocated in leukemia) Homo sapiens (Human) NA GO:0005794; GO:0005798; GO:0005886; GO:0043231 985 XM_044315760.1 95 83 84 69 136 NA NA NA NA NA NA 986 XM_044328885.1 83 13 39 58 231 Q7TN88 6.93e-63 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 987 XM_044328885.1 83 13 39 58 231 Q7TN88 2.36e-53 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 988 XM_029331345.2 157 277 109 479 287 P52569 6.67e-125 Cationic amino acid transporter 2 (CAT-2) (CAT2) (Low affinity cationic amino acid transporter 2) (Solute carrier family 7 member 2) Homo sapiens (Human) amino acid import across plasma membrane [GO:0089718]; amino acid transport [GO:0006865]; L-alpha-amino acid transmembrane transport [GO:1902475]; L-amino acid transport [GO:0015807]; L-arginine import across plasma membrane [GO:0097638]; L-arginine transmembrane transport [GO:1903826]; L-ornithine transmembrane transport [GO:1903352]; transport across blood-brain barrier [GO:0150104] GO:0000064; GO:0005886; GO:0006865; GO:0015171; GO:0015174; GO:0015179; GO:0015189; GO:0015807; GO:0030054; GO:0061459; GO:0089718; GO:0097638; GO:0150104; GO:1902475; GO:1903352; GO:1903826 989 XR_006393593.1 181 0 50 1 10 NA NA NA NA NA NA 990 XM_029342279.2 44 71 36 0 0 NA NA NA NA NA NA 991 XM_044320275.1 96 161 178 39 84 NA NA NA NA NA NA 992 XM_029358577.2 128 136 122 169 390 Q6AX73 9.68e-39 Acyl-coenzyme A diphosphatase FITM2 (EC 3.6.1.-) (Fat storage-inducing transmembrane protein 2) (Fat-inducing protein 2) Xenopus laevis (African clawed frog) cytoskeleton organization [GO:0007010]; fatty-acyl-CoA catabolic process [GO:0036115]; lipid droplet formation [GO:0140042]; lipid homeostasis [GO:0055088]; regulation of cell morphogenesis [GO:0022604] GO:0005789; GO:0007010; GO:0017129; GO:0019992; GO:0022604; GO:0036115; GO:0055088; GO:0106399; GO:0140042 993 XM_029328730.2 51 53 104 33 66 NA NA NA NA NA NA 994 XR_006396371.1 25 27 20 8 9 NA NA NA NA NA NA 995 XM_029343737.2 239 46 88 238 215 NA NA NA NA NA NA 996 XM_044327737.1 0 21 0 0 3 NA NA NA NA NA NA 997 XM_029339104.2 61 159 170 31 212 Q4KMD7 2.36e-47 Speckle targeted PIP5K1A-regulated poly(A) polymerase (Star-PAP) (EC 2.7.7.19) (RNA-binding motif protein 21) (RNA-binding protein 21) (U6 snRNA-specific terminal uridylyltransferase 1) (U6-TUTase) (EC 2.7.7.52) Danio rerio (Zebrafish) (Brachydanio rerio) mRNA polyadenylation [GO:0006378]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; RNA 3'-end processing [GO:0031123]; snRNA processing [GO:0016180] GO:0003723; GO:0003730; GO:0004652; GO:0005524; GO:0005730; GO:0006378; GO:0008270; GO:0016180; GO:0016607; GO:0016779; GO:0031123; GO:0050265; GO:0098789; GO:1990817 998 XM_044315436.1 463 870 54 663 673 C3LVL9 7.47e-87 2-aminoethylphosphonate--pyruvate transaminase (EC 2.6.1.37) (2-aminoethylphosphonate aminotransferase) (AEP transaminase) (AEPT) Vibrio cholerae serotype O1 (strain M66-2) organic phosphonate catabolic process [GO:0019700] GO:0019700; GO:0047304 999 XM_029337100.2 60 0 0 153 311 Q8TCT0 1.14e-74 Ceramide kinase (hCERK) (EC 2.7.1.138) (Acylsphingosine kinase) (Lipid kinase 4) (LK4) Homo sapiens (Human) ceramide metabolic process [GO:0006672]; glycosphingolipid metabolic process [GO:0006687]; phosphorylation [GO:0016310]; sphingolipid metabolic process [GO:0006665] GO:0000287; GO:0001727; GO:0001729; GO:0005524; GO:0005737; GO:0005886; GO:0006665; GO:0006672; GO:0006687; GO:0016020; GO:0016310; GO:0102773 1000 XM_029331517.2 24113 19969 17440 21794 15221 Q07352 2.25e-41 mRNA decay activator protein ZFP36L1 (Butyrate response factor 1) (EGF-response factor 1) (ERF-1) (TPA-induced sequence 11b) (Zinc finger protein 36, C3H1 type-like 1) (ZFP36-like 1) Homo sapiens (Human) 3'-UTR-mediated mRNA destabilization [GO:0061158]; apoptotic process [GO:0006915]; cell population proliferation [GO:0008283]; cellular response to cAMP [GO:0071320]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to raffinose [GO:0097403]; cellular response to salt stress [GO:0071472]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cellular response to tumor necrosis factor [GO:0071356]; chorio-allantoic fusion [GO:0060710]; ERK1 and ERK2 cascade [GO:0070371]; heart development [GO:0007507]; MAPK cascade [GO:0000165]; mesendoderm development [GO:0048382]; mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; multicellular organism growth [GO:0035264]; negative regulation of erythrocyte differentiation [GO:0045647]; negative regulation of mitotic cell cycle phase transition [GO:1901991]; neural tube development [GO:0021915]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; nuclear-transcribed mRNA catabolic process, deadenylation-independent decay [GO:0031086]; p38MAPK cascade [GO:0038066]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of intracellular mRNA localization [GO:1904582]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; proepicardium development [GO:0003342]; protein kinase B signaling [GO:0043491]; regulation of B cell differentiation [GO:0045577]; regulation of gene expression [GO:0010468]; regulation of keratinocyte apoptotic process [GO:1902172]; regulation of keratinocyte differentiation [GO:0045616]; regulation of keratinocyte proliferation [GO:0010837]; regulation of mRNA 3'-end processing [GO:0031440]; regulation of mRNA stability [GO:0043488]; regulation of myoblast differentiation [GO:0045661]; regulation of stem cell proliferation [GO:0072091]; response to wounding [GO:0009611]; spongiotrophoblast layer development [GO:0060712]; T cell differentiation in thymus [GO:0033077]; vasculogenesis [GO:0001570] GO:0000165; GO:0000288; GO:0000932; GO:0001570; GO:0003342; GO:0003677; GO:0003723; GO:0003729; GO:0005634; GO:0005737; GO:0005829; GO:0006397; GO:0006915; GO:0007507; GO:0008283; GO:0009611; GO:0010468; GO:0010837; GO:0014065; GO:0021915; GO:0031086; GO:0031440; GO:0032869; GO:0033077; GO:0035264; GO:0035925; GO:0038066; GO:0043488; GO:0043491; GO:0044344; GO:0045577; GO:0045600; GO:0045616; GO:0045647; GO:0045657; GO:0045661; GO:0046872; GO:0048382; GO:0051028; GO:0060710; GO:0060712; GO:0061158; GO:0070371; GO:0071320; GO:0071356; GO:0071364; GO:0071375; GO:0071385; GO:0071456; GO:0071472; GO:0071560; GO:0071889; GO:0072091; GO:0097403; GO:1900153; GO:1901991; GO:1902172; GO:1904582; GO:1990904 1001 XM_029330236.2 425 519 386 578 258 NA NA NA NA NA NA 1002 XM_029334802.2 1225 2492 848 1558 693 Q6DGV1 1.79e-74 CUGBP Elav-like family member 4 (CELF-4) (Bruno-like protein 4) (CUG-BP- and ETR-3-like factor 4) (RNA-binding protein BRUNOL-4) Danio rerio (Zebrafish) (Brachydanio rerio) mRNA splice site selection [GO:0006376]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381] GO:0000381; GO:0003723; GO:0003729; GO:0005634; GO:0005737; GO:0006376; GO:0048026; GO:1990904 1003 XM_029334802.2 1225 2492 848 1558 693 Q6DGV1 1.78e-47 CUGBP Elav-like family member 4 (CELF-4) (Bruno-like protein 4) (CUG-BP- and ETR-3-like factor 4) (RNA-binding protein BRUNOL-4) Danio rerio (Zebrafish) (Brachydanio rerio) mRNA splice site selection [GO:0006376]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381] GO:0000381; GO:0003723; GO:0003729; GO:0005634; GO:0005737; GO:0006376; GO:0048026; GO:1990904 1004 XM_029327253.2 221 120 150 140 247 Q7ZTY7 1.19e-48 Vesicle transport protein USE1 (USE1-like protein) Danio rerio (Zebrafish) (Brachydanio rerio) protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] GO:0005484; GO:0005783; GO:0005789; GO:0006890; GO:0015031; GO:0031201 1005 XM_044321329.1 85 4 131 87 93 P10394 3.58e-47 Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 1006 XM_044316962.1 34 64 0 125 109 NA NA NA NA NA NA 1007 XM_029333237.2 482 167 425 455 734 Q571I4 2.28e-29 Inactive tyrosine-protein kinase PRAG1 (Notch activation complex kinase) (PEAK1-related kinase-activating pseudokinase 1) (Sugen kinase 223) (Tyrosine-protein kinase SgK223) Mus musculus (Mouse) cell migration [GO:0016477]; negative regulation of neuron projection development [GO:0010977]; positive regulation of Rho protein signal transduction [GO:0035025]; protein phosphorylation [GO:0006468]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of Notch signaling pathway [GO:0008593] GO:0004672; GO:0005634; GO:0005737; GO:0005925; GO:0006468; GO:0008360; GO:0008593; GO:0010977; GO:0016477; GO:0035025; GO:0042802; GO:2000145 1008 XR_006395384.1 0 0 0 0 10 NA NA NA NA NA NA 1009 XR_006394037.1 4 6 8 4 3 NA NA NA NA NA NA 1010 XM_044316937.1 78 58 45 110 118 Q2TBS2 4.01e-28 39S ribosomal protein L21, mitochondrial (L21mt) (MRP-L21) Bos taurus (Bovine) NA GO:0003735; GO:0005743; GO:0005762 1011 XM_029330007.2 49 88 0 0 9 Q9TTT5 1.82e-90 Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3) Oryctolagus cuniculus (Rabbit) protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0008076; GO:0030425; GO:0034765; GO:0042383; GO:0046872; GO:0051260 1012 XM_029332212.2 3166 4533 1467 3270 2941 Q9IA76 2.09e-64 60S ribosomal protein L31 Paralichthys olivaceus (Bastard halibut) (Hippoglossus olivaceus) translation [GO:0006412] GO:0003735; GO:0005737; GO:0005840; GO:0006412; GO:1990904 1013 XM_029347826.2 2379 1287 459 1530 1291 Q0P5M9 1.55e-83 Major facilitator superfamily domain-containing protein 10 (Tetracycline transporter-like protein) Bos taurus (Bovine) apoptotic process [GO:0006915] GO:0005637; GO:0006915; GO:0022857; GO:0031526 1014 XM_044329009.1 6 35 19 38 9 Q8K2J9 2.81e-75 BTB/POZ domain-containing protein 6 Mus musculus (Mouse) neurogenesis [GO:0022008] GO:0005829; GO:0022008 1015 XM_044318556.1 24 5 0 16 10 Q68F72 2.43e-69 Solute carrier family 15 member 4 Xenopus laevis (African clawed frog) dipeptide import across plasma membrane [GO:0140206]; innate immune response [GO:0045087]; mast cell homeostasis [GO:0033023]; peptidoglycan transport [GO:0015835]; positive regulation of innate immune response [GO:0045089]; positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [GO:0070430]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of toll-like receptor 7 signaling pathway [GO:0034157]; positive regulation of toll-like receptor 8 signaling pathway [GO:0034161]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; protein transport [GO:0015031]; regulation of isotype switching to IgG isotypes [GO:0048302]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424] GO:0005290; GO:0005765; GO:0015031; GO:0015333; GO:0015647; GO:0015835; GO:0031901; GO:0033023; GO:0034157; GO:0034161; GO:0034165; GO:0036020; GO:0045087; GO:0045089; GO:0048302; GO:0070424; GO:0070430; GO:0070434; GO:0071916; GO:0140206 1016 XM_044317425.1 3059 1939 1782 3265 3106 Q64512 6.33e-81 Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (PTP36) (Protein tyrosine phosphatase DPZPTP) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) Mus musculus (Mouse) negative regulation of excitatory synapse assembly [GO:1904890]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066] GO:0001650; GO:0001933; GO:0004725; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0006470; GO:0014066; GO:0030027; GO:0030496; GO:0035335; GO:0036312; GO:0043005; GO:0044297; GO:1904890 1017 XM_044317425.1 3059 1939 1782 3265 3106 Q64512 5.74e-59 Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (PTP36) (Protein tyrosine phosphatase DPZPTP) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) Mus musculus (Mouse) negative regulation of excitatory synapse assembly [GO:1904890]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066] GO:0001650; GO:0001933; GO:0004725; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0006470; GO:0014066; GO:0030027; GO:0030496; GO:0035335; GO:0036312; GO:0043005; GO:0044297; GO:1904890 1018 XM_044317425.1 3059 1939 1782 3265 3106 Q64512 1.97e-26 Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (PTP36) (Protein tyrosine phosphatase DPZPTP) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) Mus musculus (Mouse) negative regulation of excitatory synapse assembly [GO:1904890]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066] GO:0001650; GO:0001933; GO:0004725; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0006470; GO:0014066; GO:0030027; GO:0030496; GO:0035335; GO:0036312; GO:0043005; GO:0044297; GO:1904890 1019 XM_044308895.1 249 174 135 285 950 Q15375 4.83e-83 Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) (EHK-3) (EPH-like kinase 11) (EK11) (hEK11) Homo sapiens (Human) axon guidance [GO:0007411]; brain development [GO:0007420]; branching morphogenesis of a nerve [GO:0048755]; ephrin receptor signaling pathway [GO:0048013]; modulation of chemical synaptic transmission [GO:0050804]; negative chemotaxis [GO:0050919]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of synapse assembly [GO:0051964]; nephric duct morphogenesis [GO:0072178]; neuron apoptotic process [GO:0051402]; phosphorylation [GO:0016310]; positive regulation of kinase activity [GO:0033674]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein phosphorylation [GO:0001934]; regulation of cell-cell adhesion [GO:0022407]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of postsynapse organization [GO:0099175]; regulation of protein autophosphorylation [GO:0031952]; retinal ganglion cell axon guidance [GO:0031290]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0001934; GO:0004713; GO:0004714; GO:0005004; GO:0005005; GO:0005524; GO:0005886; GO:0007169; GO:0007411; GO:0007420; GO:0008046; GO:0016310; GO:0019838; GO:0022407; GO:0030425; GO:0031290; GO:0031594; GO:0031952; GO:0033674; GO:0043005; GO:0043025; GO:0043235; GO:0043281; GO:0043525; GO:0045499; GO:0046875; GO:0048013; GO:0048671; GO:0048755; GO:0050730; GO:0050804; GO:0050919; GO:0051402; GO:0051964; GO:0070372; GO:0072178; GO:0098685; GO:0098686; GO:0098839; GO:0098978; GO:0099175 1020 XM_044320418.1 93 272 27 128 10 NA NA NA NA NA NA 1021 XM_044329182.1 28 15 15 17 27 NA NA NA NA NA NA 1022 XR_006394638.1 3255 2984 1854 4127 2692 NA NA NA NA NA NA 1023 XM_044307383.1 1380 1268 827 1167 1268 NA NA NA NA NA NA 1024 XM_029337034.2 0 0 23 31 78 Q8HYZ1 2.52e-98 Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2) Mustela putorius furo (European domestic ferret) (Mustela furo) cardiac muscle cell action potential [GO:0086001]; cellular response to hypoxia [GO:0071456]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005250; GO:0005886; GO:0005901; GO:0008076; GO:0030315; GO:0032809; GO:0034765; GO:0042383; GO:0043197; GO:0043204; GO:0044853; GO:0045211; GO:0046872; GO:0051260; GO:0070161; GO:0071456; GO:0071805; GO:0086001 1025 XM_029339898.2 0 0 69 134 0 NA NA NA NA NA NA 1026 XM_044321366.1 1372 781 967 1124 1309 Q5VXM1 7.66e-27 CUB domain-containing protein 2 Homo sapiens (Human) NA GO:0005576 1027 XR_006391826.1 0 0 0 0 25 NA NA NA NA NA NA 1028 XM_029358232.2 2970 2969 1932 2739 1895 O77475 7.94e-31 Ceramide phosphoethanolamine synthase (CPE synthase) (EC 2.7.8.n3) Drosophila melanogaster (Fruit fly) ceramide phosphoethanolamine biosynthetic process [GO:1905373] GO:0000139; GO:0002950; GO:0005794; GO:0005886; GO:1905373 1029 XM_044321412.1 187 108 0 1284 1991 J7GQ11 2.07e-76 L-tyrosine decarboxylase (TDC) (EC 4.1.1.25) Levilactobacillus brevis (Lactobacillus brevis) carboxylic acid metabolic process [GO:0019752] GO:0004837; GO:0019752; GO:0030170; GO:0036468 1030 XM_044314020.1 13 9 9 8 0 NA NA NA NA NA NA 1031 XM_044307286.1 702 366 330 728 730 O54701 9.01e-150 Sodium/potassium/calcium exchanger 2 (Na(+)/K(+)/Ca(2+)-exchange protein 2) (Retinal cone Na-Ca+K exchanger) (Solute carrier family 24 member 2) Rattus norvegicus (Rat) calcium ion import [GO:0070509]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; cellular response to high light intensity [GO:0071486]; establishment of localization in cell [GO:0051649]; ion transmembrane transport [GO:0034220]; learning [GO:0007612]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; neuron cellular homeostasis [GO:0070050]; potassium ion transmembrane transport [GO:0071805]; protein-containing complex assembly [GO:0065003]; sodium ion transmembrane transport [GO:0035725] GO:0005262; GO:0005886; GO:0006816; GO:0006874; GO:0007612; GO:0007613; GO:0008273; GO:0015293; GO:0016020; GO:0034220; GO:0035725; GO:0051649; GO:0060291; GO:0060292; GO:0065003; GO:0070050; GO:0070509; GO:0070588; GO:0071486; GO:0071805; GO:0098703 1032 XM_029344580.2 23 90 94 0 0 Q9HAC7 1.36e-165 Succinate--hydroxymethylglutarate CoA-transferase (EC 2.8.3.13) (Dermal papilla-derived protein 13) (SuccinylCoA:glutarate-CoA transferase) Homo sapiens (Human) NA GO:0005739; GO:0047369 1033 XR_003822879.2 0 0 4 0 6 NA NA NA NA NA NA 1034 XM_029347073.2 56 50 8 22 85 NA NA NA NA NA NA 1035 XM_044314070.1 210 703 393 810 470 O94876 3.95e-35 Transmembrane and coiled-coil domains protein 1 Homo sapiens (Human) endoplasmic reticulum organization [GO:0007029]; endosomal transport [GO:0016197]; endosome fission [GO:0140285]; endosome membrane tubulation [GO:0097750]; membrane fission [GO:0090148] GO:0005789; GO:0005791; GO:0005829; GO:0007029; GO:0012505; GO:0016197; GO:0042802; GO:0090148; GO:0097750; GO:0140284; GO:0140285 1036 XM_044318116.1 0 0 8 0 0 NA NA NA NA NA NA 1037 XM_044319409.1 0 10 7 0 5 Q80XJ3 1.39e-46 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 1038 XM_044319409.1 0 10 7 0 5 Q80XJ3 2.87e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 1039 XM_044319409.1 0 10 7 0 5 Q80XJ3 3.79e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 1040 XM_044319409.1 0 10 7 0 5 Q80XJ3 8.49e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 1041 XM_044319409.1 0 10 7 0 5 Q80XJ3 1.81e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 1042 XM_044319409.1 0 10 7 0 5 Q80XJ3 3.15e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 1043 XM_044319409.1 0 10 7 0 5 Q80XJ3 1.26e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 1044 XM_044319409.1 0 10 7 0 5 Q80XJ3 1.91e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 1045 XM_044319409.1 0 10 7 0 5 Q80XJ3 5.36e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 1046 XM_044319409.1 0 10 7 0 5 Q80XJ3 7.24e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 1047 XM_044319409.1 0 10 7 0 5 Q80XJ3 1.46e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 1048 XM_044319409.1 0 10 7 0 5 Q80XJ3 2.74e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 1049 XM_044319409.1 0 10 7 0 5 Q80XJ3 3.24e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 1050 XM_029339089.2 798 746 296 759 520 Q9CYL5 2.67e-39 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Mus musculus (Mouse) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070374 1051 XM_029339089.2 798 746 296 759 520 Q9CYL5 4.73e-35 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Mus musculus (Mouse) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070374 1052 XM_044321180.1 635 729 252 449 453 Q69ZW3 8.02e-64 EH domain-binding protein 1 Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; endocytosis [GO:0006897]; protein transport [GO:0015031] GO:0005654; GO:0005768; GO:0005815; GO:0005829; GO:0005886; GO:0006897; GO:0015031; GO:0030036; GO:0031941 1053 XM_044321180.1 635 729 252 449 453 Q69ZW3 2.53e-30 EH domain-binding protein 1 Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; endocytosis [GO:0006897]; protein transport [GO:0015031] GO:0005654; GO:0005768; GO:0005815; GO:0005829; GO:0005886; GO:0006897; GO:0015031; GO:0030036; GO:0031941 1054 XM_044321180.1 635 729 252 449 453 Q69ZW3 4.39e-24 EH domain-binding protein 1 Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; endocytosis [GO:0006897]; protein transport [GO:0015031] GO:0005654; GO:0005768; GO:0005815; GO:0005829; GO:0005886; GO:0006897; GO:0015031; GO:0030036; GO:0031941 1055 XR_006393869.1 0 11 0 14 10 NA NA NA NA NA NA 1056 XM_044328910.1 107 29 51 112 137 NA NA NA NA NA NA 1057 XM_029342329.2 542 355 280 265 1087 P50904 0 Ras GTPase-activating protein 1 (GAP) (GTPase-activating protein) (RasGAP) (Ras p21 protein activator) (p120GAP) Rattus norvegicus (Rat) actin cytoskeleton organization [GO:0030036]; activation of GTPase activity [GO:0090630]; blood vessel morphogenesis [GO:0048514]; cell adhesion [GO:0007155]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; male genitalia development [GO:0030539]; mitotic cytokinesis [GO:0000281]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of glucose import [GO:0046326]; positive regulation of GTPase activity [GO:0043547]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; regulation of actin filament polymerization [GO:0030833]; response to insulin [GO:0032868]; response to xenobiotic stimulus [GO:0009410]; signal transduction [GO:0007165]; vasculogenesis [GO:0001570] GO:0000281; GO:0001570; GO:0001726; GO:0001784; GO:0001934; GO:0001953; GO:0005096; GO:0005102; GO:0005161; GO:0005829; GO:0005886; GO:0007155; GO:0007162; GO:0007165; GO:0009410; GO:0016020; GO:0030036; GO:0030539; GO:0030833; GO:0030971; GO:0031965; GO:0032868; GO:0036120; GO:0043066; GO:0043422; GO:0043524; GO:0043547; GO:0044325; GO:0044344; GO:0044877; GO:0046326; GO:0048146; GO:0048514; GO:0050731; GO:0051020; GO:0071364; GO:0090630; GO:1990782 1058 XM_029326686.2 0 30 9 0 0 Q8N9H8 1.68e-89 Exonuclease mut-7 homolog (EC 3.1.-.-) (Exonuclease 3'-5' domain-containing protein 3) Homo sapiens (Human) NA GO:0003676; GO:0008408; GO:0046872 1059 XM_044309124.1 26 0 34 26 9 NA NA NA NA NA NA 1060 XM_029357056.2 131 69 52 190 421 Q9LMG7 4.91e-95 Probable inactive purple acid phosphatase 2 Arabidopsis thaliana (Mouse-ear cress) protein insertion into mitochondrial outer membrane [GO:0045040]; protein targeting to mitochondrion [GO:0006626]; regulation of carbohydrate metabolic process [GO:0006109] GO:0003993; GO:0005576; GO:0005739; GO:0005740; GO:0005768; GO:0005794; GO:0005802; GO:0006109; GO:0006626; GO:0009507; GO:0009941; GO:0030943; GO:0045040; GO:0046872 1061 XM_029335109.2 338 421 420 190 174 Q9UH36 2.22e-42 SRR1-like protein (SRR1 domain-containing protein) Homo sapiens (Human) heme biosynthetic process [GO:0006783]; microtubule-based process [GO:0007017]; regulation of circadian rhythm [GO:0042752]; regulation of heme biosynthetic process [GO:0070453]; rhythmic process [GO:0048511] GO:0005634; GO:0005737; GO:0006783; GO:0007017; GO:0042752; GO:0048511; GO:0070453 1062 XM_029330162.2 48 56 87 144 60 Q1LWH4 0 Fanconi-associated nuclease 1 (EC 3.1.21.-) (EC 3.1.4.1) (FANCD2/FANCI-associated nuclease 1) (Myotubularin-related protein 15) Danio rerio (Zebrafish) (Brachydanio rerio) DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; interstrand cross-link repair [GO:0036297]; nucleotide-excision repair [GO:0006289] GO:0000724; GO:0004528; GO:0005634; GO:0006281; GO:0006289; GO:0008409; GO:0017108; GO:0036297; GO:0046872; GO:0070336; GO:0140036 1063 XM_044318209.1 1097 466 405 836 1187 Q8N157 0 Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1) Homo sapiens (Human) central nervous system development [GO:0007417]; cilium assembly [GO:0060271]; cloaca development [GO:0035844]; heart looping [GO:0001947]; hindbrain development [GO:0030902]; Kupffer's vesicle development [GO:0070121]; left/right axis specification [GO:0070986]; morphogenesis of a polarized epithelium [GO:0001738]; motile cilium assembly [GO:0044458]; negative regulation of apoptotic process [GO:0043066]; otic vesicle development [GO:0071599]; photoreceptor cell outer segment organization [GO:0035845]; positive regulation of polarized epithelial cell differentiation [GO:0030862]; positive regulation of receptor internalization [GO:0002092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; pronephric duct morphogenesis [GO:0039023]; pronephric nephron tubule morphogenesis [GO:0039008]; protein localization [GO:0008104]; regulation of behavior [GO:0050795]; retina layer formation [GO:0010842]; specification of axis polarity [GO:0065001]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vesicle-mediated transport [GO:0016192] GO:0001738; GO:0001947; GO:0002092; GO:0005813; GO:0005814; GO:0005829; GO:0005911; GO:0005912; GO:0005929; GO:0007169; GO:0007417; GO:0008104; GO:0010842; GO:0016192; GO:0030862; GO:0030902; GO:0035844; GO:0035845; GO:0036038; GO:0036064; GO:0039008; GO:0039023; GO:0042802; GO:0043066; GO:0044458; GO:0045944; GO:0050795; GO:0060271; GO:0065001; GO:0070121; GO:0070986; GO:0071599; GO:0097730 1064 XM_029327318.2 16 1 0 13 10 NA NA NA NA NA NA 1065 XM_029355493.2 766 363 565 1391 843 Q5ZIP4 0 5'-3' exoribonuclease 2 (EC 3.1.13.-) Gallus gallus (Chicken) DNA catabolic process, exonucleolytic [GO:0000738]; mRNA processing [GO:0006397]; nuclear-transcribed mRNA catabolic process [GO:0000956]; spermatogenesis [GO:0007283] GO:0000738; GO:0000956; GO:0001147; GO:0003723; GO:0004534; GO:0005634; GO:0005654; GO:0005730; GO:0006397; GO:0007283; GO:0008409; GO:0016235; GO:0042802; GO:0046872 1066 XM_044315167.1 0 260 0 157 0 P97321 4.09e-67 Prolyl endopeptidase FAP (EC 3.4.21.26) (Dipeptidyl peptidase FAP) (EC 3.4.14.5) (Fibroblast activation protein alpha) (FAPalpha) (Gelatine degradation protease FAP) (EC 3.4.21.-) (Integral membrane serine protease) (Post-proline cleaving enzyme) (Serine integral membrane protease) (SIMP) (Surface-expressed protease) (Seprase) [Cleaved into: Antiplasmin-cleaving enzyme FAP, soluble form (APCE) (EC 3.4.14.5) (EC 3.4.21.-) (EC 3.4.21.26)] Mus musculus (Mouse) angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; melanocyte apoptotic process [GO:1902362]; melanocyte proliferation [GO:0097325]; negative regulation of cell proliferation involved in contact inhibition [GO:0060244]; negative regulation of extracellular matrix disassembly [GO:0010716]; negative regulation of extracellular matrix organization [GO:1903054]; positive regulation of execution phase of apoptosis [GO:1900119]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of cell cycle [GO:0051726]; regulation of collagen catabolic process [GO:0010710] GO:0001525; GO:0002020; GO:0004175; GO:0004252; GO:0005178; GO:0005615; GO:0005886; GO:0006508; GO:0007155; GO:0008233; GO:0008236; GO:0008239; GO:0009986; GO:0010710; GO:0010716; GO:0030027; GO:0031258; GO:0032587; GO:0042802; GO:0042803; GO:0043542; GO:0045177; GO:0045178; GO:0051603; GO:0051726; GO:0060244; GO:0070161; GO:0097325; GO:1900119; GO:1902362; GO:1903054; GO:1905368 1067 XM_044321100.1 0 0 5 6 48 Q90632 7.86e-41 Monocarboxylate transporter 3 (MCT 3) (Retinal epithelial membrane protein) (Solute carrier family 16 member 8) Gallus gallus (Chicken) monocarboxylic acid transport [GO:0015718] GO:0005886; GO:0008028; GO:0015293; GO:0015718; GO:0016020; GO:0016323 1068 XM_029338683.2 246 175 121 38 0 B3DL53 1.97e-47 Nucleoside diphosphate kinase 6 (NDK 6) (NDP kinase 6) (EC 2.7.4.6) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside diphosphate phosphorylation [GO:0006165]; UTP biosynthetic process [GO:0006228] GO:0004550; GO:0005524; GO:0006165; GO:0006183; GO:0006228; GO:0006241; GO:0046872 1069 XM_044308119.1 335 447 184 318 234 Q8R507 2.5e-108 Ribitol-5-phosphate transferase FKTN (EC 2.7.8.-) (Fukutin) (Fukuyama-type congenital muscular dystrophy protein) (Ribitol-5-phosphate transferase) Mus musculus (Mouse) negative regulation of cell population proliferation [GO:0008285]; negative regulation of JNK cascade [GO:0046329]; neuron migration [GO:0001764]; protein glycosylation [GO:0006486]; protein O-linked glycosylation [GO:0006493]; protein O-linked mannosylation [GO:0035269]; regulation of protein glycosylation [GO:0060049] GO:0000139; GO:0001764; GO:0005634; GO:0005783; GO:0005794; GO:0005801; GO:0006486; GO:0006493; GO:0008285; GO:0016780; GO:0035269; GO:0046329; GO:0060049 1070 XM_029331084.2 190 101 97 126 101 NA NA NA NA NA NA 1071 XM_029339125.2 111 0 0 57 272 O95822 3.32e-112 Malonyl-CoA decarboxylase, mitochondrial (MCD) (EC 4.1.1.9) Homo sapiens (Human) acetyl-CoA biosynthetic process [GO:0006085]; acyl-CoA metabolic process [GO:0006637]; fatty acid biosynthetic process [GO:0006633]; fatty acid oxidation [GO:0019395]; malonyl-CoA catabolic process [GO:2001294]; positive regulation of fatty acid oxidation [GO:0046321]; regulation of fatty acid beta-oxidation [GO:0031998]; regulation of glucose metabolic process [GO:0010906]; response to ischemia [GO:0002931] GO:0002931; GO:0005737; GO:0005739; GO:0005759; GO:0005777; GO:0005782; GO:0005829; GO:0006085; GO:0006633; GO:0006637; GO:0010906; GO:0019395; GO:0031998; GO:0042802; GO:0046321; GO:0050080; GO:2001294 1072 XM_029356300.2 1474 1305 1356 1329 1495 Q32LQ0 0 Glutamyl aminopeptidase (EAP) (EC 3.4.11.7) (Aminopeptidase A) (AP-A) (CD antigen CD249) Bos taurus (Bovine) cell migration [GO:0016477]; cell population proliferation [GO:0008283]; proteolysis [GO:0006508]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081] GO:0003081; GO:0004177; GO:0005886; GO:0006508; GO:0008270; GO:0008283; GO:0016477; GO:0070006 1073 XM_029355835.2 166 138 212 142 142 NA NA NA NA NA NA 1074 XM_029343800.2 22 8 0 0 14 Q5PQ71 2.99e-60 Isochorismatase domain-containing protein 2 Xenopus laevis (African clawed frog) NA NA 1075 XM_029334049.2 0 0 9 16 12 Q61184 2.03e-21 Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor) Mus musculus (Mouse) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; circadian rhythm [GO:0007623]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of insulin secretion [GO:0046676] GO:0004930; GO:0005886; GO:0007186; GO:0007193; GO:0007623; GO:0008502; GO:0042562; GO:0043025; GO:0043235; GO:0046676; GO:0097159 1076 XM_029325021.2 835 621 352 731 818 Q9ULR3 9.05e-120 Protein phosphatase 1H (EC 3.1.3.16) Homo sapiens (Human) protein dephosphorylation [GO:0006470] GO:0004721; GO:0005634; GO:0005654; GO:0005737; GO:0006470; GO:0017018; GO:0042802; GO:0098978 1077 XM_029348034.2 17 0 100 385 337 Q86WI1 0 Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) Homo sapiens (Human) immune response [GO:0006955]; sensory perception of sound [GO:0007605] GO:0005615; GO:0005829; GO:0006955; GO:0007605; GO:0016020; GO:0032426; GO:0038023; GO:0120234 1078 XM_029338624.2 41 16 22 0 0 NA NA NA NA NA NA 1079 XR_006394947.1 0 3 0 13 50 NA NA NA NA NA NA 1080 XM_044313378.1 9 4 4 1 33 NA NA NA NA NA NA 1081 XM_029326317.2 202 81 57 345 179 NA NA NA NA NA NA 1082 XM_044312392.1 722 1090 267 336 350 A6NED2 3.09e-39 RCC1 domain-containing protein 1 Homo sapiens (Human) chromatin organization [GO:0006325] GO:0005694; GO:0005829; GO:0005886; GO:0006325 1083 XM_029332245.2 296 375 40 0 67 NA NA NA NA NA NA 1084 XM_044309586.1 1540 189 207 904 430 NA NA NA NA NA NA 1085 XM_029352787.2 285 271 251 321 210 Q766D5 4.21e-24 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Mus musculus (Mouse) chondroitin sulfate biosynthetic process [GO:0030206] GO:0008376; GO:0030206; GO:0032580; GO:0033842; GO:0047238 1086 XM_044312134.1 59 20 9 0 38 NA NA NA NA NA NA 1087 XM_029343380.2 389 258 286 548 638 NA NA NA NA NA NA 1088 XM_044306759.1 9 44 18 3 49 NA NA NA NA NA NA 1089 XM_029348470.2 166 78 114 14 43 C3LWF0 4.86e-23 L-threonine 3-dehydrogenase (TDH) (EC 1.1.1.103) Vibrio cholerae serotype O1 (strain M66-2) L-threonine catabolic process to glycine [GO:0019518] GO:0005737; GO:0008270; GO:0008743; GO:0019518 1090 XM_044322100.1 344 397 226 141 284 P55112 4.09e-42 Zinc metalloproteinase nas-4 (EC 3.4.24.-) (Nematode astacin 4) Caenorhabditis elegans proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0006508; GO:0008270 1091 XM_044328102.1 0 3 0 0 45 NA NA NA NA NA NA 1092 XM_044316542.1 712 277 96 437 169 NA NA NA NA NA NA 1093 XM_044316581.1 212 302 155 391 226 Q5ZML9 7.02e-135 Actin-histidine N-methyltransferase (EC 2.1.1.85) (Protein-L-histidine N-tele-methyltransferase) (SET domain-containing protein 3) Gallus gallus (Chicken) actin modification [GO:0030047]; peptidyl-histidine methylation [GO:0018021]; peptidyl-lysine dimethylation [GO:0018027]; peptidyl-lysine monomethylation [GO:0018026]; peptidyl-lysine trimethylation [GO:0018023]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0003713; GO:0003779; GO:0005737; GO:0016279; GO:0018021; GO:0018023; GO:0018026; GO:0018027; GO:0018064; GO:0030047; GO:0042800; GO:0045893; GO:0045944; GO:0046975 1094 XR_006394602.1 0 0 17 1 8 NA NA NA NA NA NA 1095 XM_044319341.1 6 2 0 0 5 NA NA NA NA NA NA 1096 XM_044308674.1 28 41 13 2 20 NA NA NA NA NA NA 1097 XM_044310876.1 163 220 43 33 13 NA NA NA NA NA NA 1098 XM_029323433.2 16 123 0 51 32 Q86VP3 6.76e-155 Phosphofurin acidic cluster sorting protein 2 (PACS-2) (PACS1-like protein) Homo sapiens (Human) apoptotic process [GO:0006915]; autophagosome assembly [GO:0000045]; endoplasmic reticulum calcium ion homeostasis [GO:0032469]; mitochondrion-endoplasmic reticulum membrane tethering [GO:1990456]; protein localization to phagophore assembly site [GO:0034497]; protein localization to plasma membrane [GO:0072659] GO:0000045; GO:0005739; GO:0005783; GO:0006915; GO:0032469; GO:0034497; GO:0044325; GO:0072659; GO:1990456 1099 XM_029333904.2 412 348 262 513 404 Q8C0Q3 3.19e-25 Tetratricopeptide repeat protein 34 (TPR repeat protein 34) Mus musculus (Mouse) NA NA 1100 XM_044310839.1 304 392 729 291 0 Q7RTR2 2.06e-72 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 1101 XM_044310839.1 304 392 729 291 0 Q7RTR2 7.44e-68 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 1102 XM_044310839.1 304 392 729 291 0 Q7RTR2 9.59e-67 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 1103 XM_044310839.1 304 392 729 291 0 Q7RTR2 1.25e-64 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 1104 XM_044310839.1 304 392 729 291 0 Q7RTR2 1.34e-60 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 1105 XM_044310839.1 304 392 729 291 0 Q7RTR2 3.19e-58 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 1106 XM_029331790.2 1126 893 516 938 1165 Q498M4 0 WD repeat-containing protein 5 Rattus norvegicus (Rat) gluconeogenesis [GO:0006094]; histone H3 acetylation [GO:0043966]; histone H3-K14 acetylation [GO:0044154]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; negative regulation of histone H3-K4 methylation [GO:0051572]; neuron projection development [GO:0031175]; peptidyl-lysine methylation [GO:0018022]; positive regulation of gluconeogenesis [GO:0045722]; positive regulation of histone H3-K4 methylation [GO:0051571]; regulation of cell cycle [GO:0051726]; regulation of cell division [GO:0051302]; regulation of DNA-templated transcription [GO:0006355]; regulation of dosage compensation by inactivation of X chromosome [GO:1900095]; regulation of embryonic development [GO:0045995]; regulation of histone deacetylation [GO:0031063]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tubulin deacetylation [GO:0090043]; skeletal system development [GO:0001501]; transcription initiation-coupled chromatin remodeling [GO:0045815] GO:0000123; GO:0001501; GO:0005634; GO:0006094; GO:0006355; GO:0006357; GO:0018022; GO:0031063; GO:0031175; GO:0035064; GO:0035097; GO:0042393; GO:0042800; GO:0043966; GO:0043981; GO:0043982; GO:0043984; GO:0044154; GO:0044545; GO:0044665; GO:0044666; GO:0045722; GO:0045815; GO:0045995; GO:0048188; GO:0051302; GO:0051568; GO:0051571; GO:0051572; GO:0051726; GO:0071339; GO:0090043; GO:0140672; GO:1900095 1107 XM_044307683.1 42 10 28 125 48 NA NA NA NA NA NA 1108 XM_044310092.1 10 34 28 14 85 NA NA NA NA NA NA 1109 XM_029357420.2 295 194 177 289 118 NA NA NA NA NA NA 1110 XM_029347232.2 4180 4314 1827 3623 3394 P63100 1.16e-96 Calcineurin subunit B type 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1) Rattus norvegicus (Rat) branching involved in blood vessel morphogenesis [GO:0001569]; calcineurin-mediated signaling [GO:0097720]; calcineurin-NFAT signaling cascade [GO:0033173]; epithelial to mesenchymal transition [GO:0001837]; heart development [GO:0007507]; lung epithelial cell differentiation [GO:0060487]; myelination in peripheral nervous system [GO:0022011]; positive regulation of transcription by RNA polymerase II [GO:0045944]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; protein dephosphorylation [GO:0006470]; protein import into nucleus [GO:0006606]; protein localization to nucleus [GO:0034504]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; regulation of synaptic vesicle cycle [GO:0098693]; Schwann cell development [GO:0014044] GO:0001569; GO:0001837; GO:0004721; GO:0005509; GO:0005829; GO:0005955; GO:0006470; GO:0006606; GO:0007507; GO:0008597; GO:0014044; GO:0016018; GO:0019899; GO:0019902; GO:0019904; GO:0022011; GO:0033173; GO:0034504; GO:0042383; GO:0045202; GO:0045944; GO:0060487; GO:0097720; GO:0098685; GO:0098686; GO:0098688; GO:0098693; GO:0098794; GO:0098978; GO:0099149; GO:0099170 1111 XM_029343055.2 1702 1918 499 1267 1543 Q9C005 9.07e-28 Protein dpy-30 homolog (Dpy-30-like protein) (Dpy-30L) Homo sapiens (Human) endosomal transport [GO:0016197]; histone H3-K4 methylation [GO:0051568]; transcription initiation-coupled chromatin remodeling [GO:0045815] GO:0005634; GO:0005654; GO:0005794; GO:0005802; GO:0016197; GO:0035097; GO:0042802; GO:0042803; GO:0044665; GO:0044666; GO:0045815; GO:0048188; GO:0051568; GO:0071339 1112 XM_029341066.2 9 24 29 14 42 NA NA NA NA NA NA 1113 XM_044325639.1 369 202 515 20 0 Q91ZV3 3.32e-22 Discoidin, CUB and LCCL domain-containing protein 2 (Endothelial and smooth muscle cell-derived neuropilin-like protein) Mus musculus (Mouse) negative regulation of cell growth [GO:0030308]; wound healing [GO:0042060] GO:0005886; GO:0009986; GO:0030308; GO:0038023; GO:0042060 1114 XM_029346480.2 0 0 0 11 0 Q6DHC3 4.36e-98 Probable mitochondrial glutathione transporter SLC25A40 (Solute carrier family 25 member 40) Danio rerio (Zebrafish) (Brachydanio rerio) mitochondrial transmembrane transport [GO:1990542] GO:0005739; GO:0005743; GO:1990542 1115 XM_044321635.1 3 1 12 2 0 P49914 6.61e-42 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) (5,10-methenyl-tetrahydrofolate synthetase) (MTHFS) (Methenyl-THF synthetase) Homo sapiens (Human) folic acid catabolic process [GO:0046657]; folic acid metabolic process [GO:0046655]; folic acid-containing compound biosynthetic process [GO:0009396]; formate metabolic process [GO:0015942]; glutamate metabolic process [GO:0006536]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653] GO:0005524; GO:0005542; GO:0005737; GO:0005739; GO:0005759; GO:0005829; GO:0006536; GO:0009396; GO:0015942; GO:0030272; GO:0035999; GO:0046653; GO:0046655; GO:0046657; GO:0046872 1116 XM_044308117.1 8 0 0 0 0 NA NA NA NA NA NA 1117 XM_044313127.1 970 733 1246 893 893 O35218 0 Cleavage and polyadenylation specificity factor subunit 2 (Cleavage and polyadenylation specificity factor 100 kDa subunit) (CPSF 100 kDa subunit) Mus musculus (Mouse) mRNA 3'-end processing by stem-loop binding and cleavage [GO:0006398]; mRNA polyadenylation [GO:0006378]; pre-mRNA cleavage required for polyadenylation [GO:0098789] GO:0003723; GO:0005847; GO:0006378; GO:0006398; GO:0098789; GO:0098794; GO:0098978 1118 XM_044326137.1 0 0 0 4 7 P09523 1.21e-26 Enzymatic polyprotein [Includes: Aspartic protease (EC 3.4.23.-); Endonuclease; Reverse transcriptase (EC 2.7.7.49)] Figwort mosaic virus (strain DxS) (FMV) proteolysis [GO:0006508] GO:0003964; GO:0004190; GO:0004519; GO:0006508 1119 XM_044318083.1 0 1 0 7 0 Q5F371 4.8e-114 Protein strawberry notch homolog 1 Gallus gallus (Chicken) regulation of DNA-templated transcription [GO:0006355]; regulation of response to stimulus [GO:0048583] GO:0005634; GO:0006355; GO:0031490; GO:0042393; GO:0048583 1120 XM_044320965.1 28 24 0 59 50 NA NA NA NA NA NA 1121 XM_029340253.2 254 155 71 145 191 NA NA NA NA NA NA 1122 XM_029338792.2 2032 2334 1505 1665 1587 B1H2N3 4.49e-117 Calcium uptake protein 1, mitochondrial (Calcium-binding atopy-related autoantigen 1 homolog) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) calcium ion import [GO:0070509]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrial calcium ion transmembrane transport [GO:0006851]; positive regulation of mitochondrial calcium ion concentration [GO:0051561] GO:0005509; GO:0005743; GO:0005758; GO:0006851; GO:0031966; GO:0051560; GO:0051561; GO:0070509; GO:1990246 1123 XM_029332955.2 296 521 333 452 489 Q9ESP5 3.69e-23 Fez family zinc finger protein 2 (Forebrain embryonic zinc finger-like protein 2) (Zinc finger protein 312) (Zinc finger protein Fez-like) Mus musculus (Mouse) axonal fasciculation [GO:0007413]; cell dedifferentiation [GO:0043697]; cerebral cortex GABAergic interneuron migration [GO:0021853]; cerebral cortex neuron differentiation [GO:0021895]; commitment of neuronal cell to specific neuron type in forebrain [GO:0021902]; dendrite development [GO:0016358]; dentate gyrus development [GO:0021542]; forebrain anterior/posterior pattern specification [GO:0021797]; forebrain development [GO:0030900]; GABAergic neuron differentiation [GO:0097154]; locomotory behavior [GO:0007626]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron differentiation [GO:0030182]; neuron fate determination [GO:0048664]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of neuron differentiation [GO:0045666]; regulation of axon guidance [GO:1902667]; regulation of DNA-templated transcription [GO:0006355]; regulation of neurogenesis [GO:0050767]; telencephalon development [GO:0021537] GO:0000122; GO:0000976; GO:0000978; GO:0000981; GO:0001227; GO:0001228; GO:0003682; GO:0005634; GO:0006355; GO:0007413; GO:0007626; GO:0008285; GO:0016358; GO:0021537; GO:0021542; GO:0021797; GO:0021853; GO:0021895; GO:0021902; GO:0030182; GO:0030900; GO:0043565; GO:0043697; GO:0045665; GO:0045666; GO:0045893; GO:0046872; GO:0048664; GO:0050767; GO:0097154; GO:1902667 1124 XM_029339469.2 83 93 0 126 936 P51612 3.57e-114 DNA repair protein complementing XP-C cells homolog (Xeroderma pigmentosum group C-complementing protein homolog) (p125) Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]; mitotic intra-S DNA damage checkpoint signaling [GO:0031573]; nucleotide-excision repair [GO:0006289]; positive regulation of DNA-templated transcription [GO:0045893]; pyrimidine dimer repair by nucleotide-excision repair [GO:0000720]; regulation of gluconeogenesis [GO:0006111]; regulation of mitotic cell cycle phase transition [GO:1901990]; response to auditory stimulus [GO:0010996]; response to UV-B [GO:0010224]; response to xenobiotic stimulus [GO:0009410]; UV-damage excision repair [GO:0070914] GO:0000109; GO:0000111; GO:0000720; GO:0003684; GO:0003697; GO:0003713; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005739; GO:0005829; GO:0005886; GO:0006111; GO:0006281; GO:0006289; GO:0006298; GO:0006974; GO:0009410; GO:0010224; GO:0010996; GO:0031573; GO:0043231; GO:0044877; GO:0045893; GO:0061629; GO:0070914; GO:0071942; GO:0090734; GO:0140612; GO:1901990 1125 XM_029324742.2 744 193 105 85 93 NA NA NA NA NA NA 1126 XM_044326331.1 3237 3799 1560 3532 1129 Q28728 1.23e-134 Sodium/myo-inositol cotransporter 2 (Na(+)/myo-inositol cotransporter 2) (Sodium-dependent glucose cotransporter) (Sodium/glucose cotransporter KST1) (rKST1) (Sodium/myo-inositol transporter 2) (SMIT2) (Solute carrier family 5 member 11) Oryctolagus cuniculus (Rabbit) apoptotic process [GO:0006915]; carbohydrate transport [GO:0008643]; myo-inositol transport [GO:0015798]; regulation of transporter activity [GO:0032409]; sodium ion transport [GO:0006814] GO:0005365; GO:0005886; GO:0006814; GO:0006915; GO:0008643; GO:0015293; GO:0015798; GO:0016324; GO:0032409 1127 XR_003825339.2 1627 1199 931 2005 1704 NA NA NA NA NA NA 1128 XM_044309630.1 0 4 0 6 7 NA NA NA NA NA NA 1129 XM_044324790.1 6 0 0 4 0 NA NA NA NA NA NA 1130 XR_006396184.1 606 207 274 824 921 Q5UQ13 7.38e-30 Collagen-like protein 2 Acanthamoeba polyphaga mimivirus (APMV) NA GO:0044423 1131 XR_006396184.1 606 207 274 824 921 Q5UQ13 1.29e-26 Collagen-like protein 2 Acanthamoeba polyphaga mimivirus (APMV) NA GO:0044423 1132 XR_006396184.1 606 207 274 824 921 Q5UQ13 6.19e-24 Collagen-like protein 2 Acanthamoeba polyphaga mimivirus (APMV) NA GO:0044423 1133 XR_006396184.1 606 207 274 824 921 Q5UQ13 8.19e-24 Collagen-like protein 2 Acanthamoeba polyphaga mimivirus (APMV) NA GO:0044423 1134 XR_006396184.1 606 207 274 824 921 Q5UQ13 1.03e-22 Collagen-like protein 2 Acanthamoeba polyphaga mimivirus (APMV) NA GO:0044423 1135 XR_006396184.1 606 207 274 824 921 Q5UQ13 1.29e-22 Collagen-like protein 2 Acanthamoeba polyphaga mimivirus (APMV) NA GO:0044423 1136 XR_006396184.1 606 207 274 824 921 Q5UQ13 1.48e-22 Collagen-like protein 2 Acanthamoeba polyphaga mimivirus (APMV) NA GO:0044423 1137 XR_006396184.1 606 207 274 824 921 Q5UQ13 2.99e-22 Collagen-like protein 2 Acanthamoeba polyphaga mimivirus (APMV) NA GO:0044423 1138 XM_044308711.1 8 1 0 0 0 NA NA NA NA NA NA 1139 XM_029356410.2 11 7 7 9 0 NA NA NA NA NA NA 1140 XM_044314345.1 68 31 76 667 747 NA NA NA NA NA NA 1141 XM_044312664.1 0 0 11 5 7 P61752 4.19e-30 Histamine H2 receptor (H2R) (HH2R) (Gastric receptor I) Pongo pygmaeus (Bornean orangutan) gastric acid secretion [GO:0001696]; positive regulation of vasoconstriction [GO:0045907] GO:0001696; GO:0004969; GO:0005886; GO:0045907 1142 XM_044315992.1 56 24 7 81 92 Q5DU56 2.3e-56 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 1143 XM_044315992.1 56 24 7 81 92 Q5DU56 9.11e-51 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 1144 XM_044315992.1 56 24 7 81 92 Q5DU56 1.91e-49 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 1145 XM_044315992.1 56 24 7 81 92 Q5DU56 9.7e-49 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 1146 XM_044315992.1 56 24 7 81 92 Q5DU56 3.61e-45 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 1147 XM_044315992.1 56 24 7 81 92 Q5DU56 3.55e-44 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 1148 XM_044315992.1 56 24 7 81 92 Q5DU56 1.36e-41 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 1149 XR_006396525.1 0 99 27 153 74 NA NA NA NA NA NA 1150 XR_006392972.1 41 2 25 5 151 NA NA NA NA NA NA 1151 XM_029356793.2 380 333 273 558 352 P05208 2.51e-56 Chymotrypsin-like elastase family member 2A (EC 3.4.21.71) (Elastase-2) (Elastase-2A) Mus musculus (Mouse) insulin catabolic process [GO:1901143]; proteolysis [GO:0006508]; regulation of insulin secretion [GO:0050796]; regulation of platelet aggregation [GO:0090330]; response to insulin [GO:0032868] GO:0004175; GO:0004252; GO:0005576; GO:0005615; GO:0006508; GO:0017171; GO:0032868; GO:0036457; GO:0050796; GO:0062023; GO:0090330; GO:1901143 1152 XM_029342112.2 8301 4422 3515 5188 5430 Q9P2H3 0 Intraflagellar transport protein 80 homolog (WD repeat-containing protein 56) Homo sapiens (Human) articular cartilage development [GO:0061975]; bone mineralization involved in bone maturation [GO:0035630]; cilium assembly [GO:0060271]; endochondral ossification [GO:0001958]; growth plate cartilage chondrocyte differentiation [GO:0003418]; intraciliary anterograde transport [GO:0035720]; keratinocyte proliferation [GO:0043616]; limb development [GO:0060173]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; non-canonical Wnt signaling pathway [GO:0035567]; non-motile cilium assembly [GO:1905515]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; receptor localization to non-motile cilium [GO:0097500]; smoothened signaling pathway [GO:0007224] GO:0001649; GO:0001958; GO:0003418; GO:0005737; GO:0005813; GO:0005929; GO:0007224; GO:0010839; GO:0030992; GO:0033687; GO:0035567; GO:0035630; GO:0035720; GO:0036064; GO:0043616; GO:0060173; GO:0060271; GO:0061975; GO:0097500; GO:0097542; GO:0097731; GO:1905515; GO:2000051 1153 XM_029343979.2 1468 897 340 1049 818 B9EJ86 0 Oxysterol-binding protein-related protein 8 (ORP-8) (OSBP-related protein 8) Mus musculus (Mouse) activation of protein kinase B activity [GO:0032148]; fat cell differentiation [GO:0045444]; negative regulation of cell migration [GO:0030336]; negative regulation of sequestering of triglyceride [GO:0010891]; phospholipid transport [GO:0015914]; positive regulation of glucose import [GO:0046326]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of protein kinase B signaling [GO:0051897]; protein localization to nuclear pore [GO:0090204] GO:0001786; GO:0005783; GO:0005789; GO:0005829; GO:0010891; GO:0015248; GO:0015485; GO:0015914; GO:0016020; GO:0030336; GO:0031965; GO:0032148; GO:0032541; GO:0032934; GO:0043231; GO:0045444; GO:0046326; GO:0046628; GO:0051897; GO:0070273; GO:0090204; GO:0140343 1154 XM_029346999.2 267 112 388 261 717 Q90632 2.03e-41 Monocarboxylate transporter 3 (MCT 3) (Retinal epithelial membrane protein) (Solute carrier family 16 member 8) Gallus gallus (Chicken) monocarboxylic acid transport [GO:0015718] GO:0005886; GO:0008028; GO:0015293; GO:0015718; GO:0016020; GO:0016323 1155 XR_003824770.2 79 75 204 152 177 NA NA NA NA NA NA 1156 XM_044311807.1 418 348 112 327 265 NA NA NA NA NA NA 1157 XM_029325250.2 2743 2456 1352 1983 1484 A3KPN8 9.57e-172 Tetratricopeptide repeat protein 38 (TPR repeat protein 38) Danio rerio (Zebrafish) (Brachydanio rerio) NA NA 1158 XM_044325365.1 45 0 34 2 34 O15439 0 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 1159 XM_044322856.1 4733 2849 2162 4015 4146 P15690 0 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (EC 7.1.1.2) (Complex I-75kD) (CI-75kD) Bos taurus (Bovine) apoptotic mitochondrial changes [GO:0008637]; ATP metabolic process [GO:0046034]; cellular respiration [GO:0045333]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrial respiratory chain complex I assembly [GO:0032981]; reactive oxygen species metabolic process [GO:0072593]; regulation of mitochondrial membrane potential [GO:0051881] GO:0005739; GO:0005743; GO:0005747; GO:0005758; GO:0006120; GO:0008137; GO:0008637; GO:0032981; GO:0045333; GO:0046034; GO:0046872; GO:0051537; GO:0051539; GO:0051881; GO:0072593 1160 XM_044317299.1 103 187 323 454 519 P30997 2.19e-45 Catenin alpha-2 (Alpha N-catenin) (Neural alpha-catenin) Gallus gallus (Chicken) axonogenesis [GO:0007409]; brain morphogenesis [GO:0048854]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; dendrite morphogenesis [GO:0048813]; epithelial cell differentiation [GO:0030855]; neural crest cell migration [GO:0001755]; protein localization [GO:0008104]; regulation of synapse structural plasticity [GO:0051823]; trigeminal ganglion formation [GO:0061561] GO:0001755; GO:0005198; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0005912; GO:0007409; GO:0008013; GO:0008104; GO:0015629; GO:0016342; GO:0016477; GO:0030424; GO:0030855; GO:0045296; GO:0048813; GO:0048854; GO:0051015; GO:0051823; GO:0061561; GO:0098609 1161 XM_044326962.1 7 9 1 0 39 NA NA NA NA NA NA 1162 XM_044314453.1 86 22 21 15 43 P59046 6.91e-43 NACHT, LRR and PYD domains-containing protein 12 (Monarch-1) (PYRIN-containing APAF1-like protein 7) (Regulated by nitric oxide) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cellular response to cytokine stimulus [GO:0071345]; dendritic cell migration [GO:0036336]; ERK1 and ERK2 cascade [GO:0070371]; negative regulation of cytokine production [GO:0001818]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of signal transduction [GO:0009968]; negative regulation of Toll signaling pathway [GO:0045751]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of inflammatory response [GO:0050727]; regulation of interleukin-18 production [GO:0032661]; signal transduction [GO:0007165] GO:0001818; GO:0005524; GO:0005737; GO:0005829; GO:0006919; GO:0007165; GO:0008656; GO:0009968; GO:0031953; GO:0032088; GO:0032661; GO:0032692; GO:0032715; GO:0032731; GO:0036336; GO:0038061; GO:0043122; GO:0043124; GO:0043281; GO:0045345; GO:0045751; GO:0050727; GO:0050728; GO:0050729; GO:0070371; GO:0070373; GO:0071345; GO:1901223; GO:1901224 1163 XM_029344188.2 265 153 83 140 152 NA NA NA NA NA NA 1164 XM_029334917.2 219 113 121 408 507 Q7Z3V4 0 Ubiquitin-protein ligase E3B (EC 2.3.2.26) (HECT-type ubiquitin transferase E3B) Homo sapiens (Human) protein polyubiquitination [GO:0000209]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000209; GO:0006511; GO:0061630 1165 XM_044324462.1 1166 1302 717 1263 1504 O43102 0 H/ACA ribonucleoprotein complex subunit cbf5 (EC 5.4.99.-) (Centromere-binding factor 5) (H/ACA snoRNP protein cbf5) (Small nucleolar RNP protein cbf5) Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus) box H/ACA RNA 3'-end processing [GO:0000495]; mRNA pseudouridine synthesis [GO:1990481]; rRNA pseudouridine synthesis [GO:0031118]; snRNA pseudouridine synthesis [GO:0031120] GO:0000495; GO:0003677; GO:0003723; GO:0005874; GO:0009982; GO:0031118; GO:0031120; GO:0031429; GO:1990481 1166 XM_044329306.1 459 28 26 381 14 NA NA NA NA NA NA 1167 XM_029324313.2 0 1 0 6 7 NA NA NA NA NA NA 1168 XM_044315579.1 0 31 0 33 3 NA NA NA NA NA NA 1169 XR_003827083.2 29 0 33 5 12 NA NA NA NA NA NA 1170 XM_029338104.2 83 83 62 125 21 Q7ZXK9 0 Notchless protein homolog 1 Xenopus laevis (African clawed frog) Notch signaling pathway [GO:0007219] GO:0005730; GO:0007219 1171 XR_006392422.1 5867 1471 554 3884 460 Q61153 2.48e-50 Type I iodothyronine deiodinase (EC 1.21.99.4) (5DI) (DIOI) (Type 1 DI) (Type-I 5'-deiodinase) Mus musculus (Mouse) amino acid metabolic process [GO:0006520]; hormone biosynthetic process [GO:0042446]; thyroid hormone metabolic process [GO:0042403] GO:0004800; GO:0005789; GO:0006520; GO:0008430; GO:0042403; GO:0042446 1172 XM_044317943.1 39 26 9 0 5 Q8K430 3.98e-37 Kelch-like protein 17 (Actinfilin) Rattus norvegicus (Rat) actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; protein ubiquitination [GO:0016567]; regulation protein catabolic process at postsynapse [GO:0140252] GO:0007420; GO:0014069; GO:0015629; GO:0016567; GO:0030036; GO:0031208; GO:0032839; GO:0043025; GO:0051015; GO:0060090; GO:0098794; GO:0098978; GO:0140252 1173 XM_044315723.1 1345 380 201 205 304 NA NA NA NA NA NA 1174 XM_044321078.1 105 21 36 111 24 C3ZQF9 3.23e-27 QRFP-like peptide receptor Branchiostoma floridae (Florida lancelet) (Amphioxus) cellular response to peptide [GO:1901653]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:1901653 1175 XM_044326693.1 187 59 19 9 21 NA NA NA NA NA NA 1176 XR_006394031.1 51 0 0 0 92 NA NA NA NA NA NA 1177 XM_029347234.2 168 0 117 59 241 NA NA NA NA NA NA 1178 XM_044322209.1 0 0 1 2 12 NA NA NA NA NA NA 1179 XM_029350701.2 616 0 0 616 0 F1P4W9 0 Cilia- and flagella-associated protein 65 (Coiled-coil domain-containing protein 108) Gallus gallus (Chicken) flagellated sperm motility [GO:0030317]; sperm axoneme assembly [GO:0007288] GO:0001669; GO:0002080; GO:0005737; GO:0005886; GO:0007288; GO:0030317; GO:0036126; GO:0097225 1180 XM_044327203.1 0 10 58 0 163 Q9LUE3 1.18e-27 Bidirectional sugar transporter SWEET10 (AtSWEET10) (Protein SUGARS WILL EVENTUALLY BE EXPORTED TRANSPORTERS 10) Arabidopsis thaliana (Mouse-ear cress) carbohydrate transport [GO:0008643]; long-day photoperiodism [GO:0048571]; sucrose transport [GO:0015770] GO:0005886; GO:0008515; GO:0008643; GO:0015770; GO:0016020; GO:0048571; GO:0051119 1181 XR_006392647.1 15 21 24 7 27 NA NA NA NA NA NA 1182 XM_044316068.1 60 48 20 6 22 NA NA NA NA NA NA 1183 XM_029333500.2 315 446 484 2681 1254 P58027 3.53e-145 Amine oxidase [flavin-containing] A (EC 1.4.3.21) (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A) Canis lupus familiaris (Dog) (Canis familiaris) catecholamine metabolic process [GO:0006584]; neurotransmitter catabolic process [GO:0042135] GO:0005739; GO:0005741; GO:0006584; GO:0008131; GO:0042135; GO:0050660; GO:0052595; GO:0052596; GO:0097621 1184 XM_044320113.1 0 6 2 0 0 Q5U243 3.39e-141 CAP-Gly domain-containing linker protein 3 (Cytoplasmic linker protein 170-related 59 kDa protein) (CLIP-170-related 59 kDa protein) (CLIPR-59) Xenopus laevis (African clawed frog) NA GO:0005795 1185 XR_006393660.1 16 0 7 0 6 NA NA NA NA NA NA 1186 XR_006396956.1 809 411 814 407 241 NA NA NA NA NA NA 1187 XR_003828442.2 19 8 0 0 0 NA NA NA NA NA NA 1188 XM_029335022.2 71295 151397 64506 81065 81071 P47826 1.3e-135 60S acidic ribosomal protein P0 (60S ribosomal protein L10E) Gallus gallus (Chicken) cytoplasmic translation [GO:0002181]; ribosomal large subunit assembly [GO:0000027] GO:0000027; GO:0002181; GO:0003735; GO:0005634; GO:0022625; GO:0070180 1189 XM_029331544.2 133 76 100 122 90 F4IYM4 1.69e-39 Protein DEFECTIVE IN EXINE FORMATION 1 Arabidopsis thaliana (Mouse-ear cress) cell wall organization [GO:0071555]; pollen exine formation [GO:0010584]; pollen wall assembly [GO:0010208] GO:0000137; GO:0005509; GO:0005783; GO:0005829; GO:0005886; GO:0010208; GO:0010584; GO:0016020; GO:0071555 1190 XM_029356141.2 8 6 2 7 3 P79401 2.44e-103 Cytochrome P450 3A29 (EC 1.14.14.1) (CYPIIIA29) Sus scrofa (Pig) cellular response to type I interferon [GO:0071357]; oxidative demethylation [GO:0070989]; steroid metabolic process [GO:0008202] GO:0004497; GO:0005506; GO:0005789; GO:0008202; GO:0008395; GO:0020037; GO:0050649; GO:0070330; GO:0070989; GO:0071357 1191 XM_029352733.2 105 31 41 95 18 P50219 1.13e-24 Motor neuron and pancreas homeobox protein 1 (Homeobox protein HB9) Homo sapiens (Human) central nervous system development [GO:0007417]; endocrine pancreas development [GO:0031018]; neuron projection morphogenesis [GO:0048812]; spinal cord motor neuron cell fate specification [GO:0021520] GO:0000785; GO:0000981; GO:0001227; GO:0005634; GO:0005654; GO:0005730; GO:0005829; GO:0007417; GO:0021520; GO:0031018; GO:0048812; GO:1990837 1192 XM_029351749.2 30 14 31 72 66 Q63357 0 Unconventional myosin-Id (Myosin heavy chain myr 4) Rattus norvegicus (Rat) actin filament organization [GO:0007015]; cellular localization [GO:0051641]; forebrain development [GO:0030900]; protein transport [GO:0015031]; vesicle transport along actin filament [GO:0030050] GO:0000146; GO:0005516; GO:0005524; GO:0005737; GO:0005769; GO:0005790; GO:0005886; GO:0005902; GO:0005903; GO:0005938; GO:0007015; GO:0015031; GO:0015629; GO:0016323; GO:0016459; GO:0019904; GO:0030050; GO:0030424; GO:0030673; GO:0030900; GO:0031410; GO:0031982; GO:0043005; GO:0043025; GO:0043204; GO:0043209; GO:0044853; GO:0048306; GO:0051015; GO:0051641; GO:0097440 1193 XM_029353745.2 1080 603 733 1002 3 NA NA NA NA NA NA 1194 XM_029325121.2 209 306 0 103 0 A0JMQ7 1.69e-21 Microtubule-associated tumor suppressor 1 homolog A (Mitochondrial tumor suppressor 1 homolog A) Danio rerio (Zebrafish) (Brachydanio rerio) cell cycle [GO:0007049] GO:0005634; GO:0005739; GO:0005794; GO:0005886; GO:0007049; GO:0008017 1195 XM_044327481.1 20 18 0 0 15 NA NA NA NA NA NA 1196 XM_044325893.1 120 81 90 79 80 NA NA NA NA NA NA 1197 XM_029347466.2 0 120 0 0 0 NA NA NA NA NA NA 1198 XM_044325450.1 0 5 0 0 12 Q9GLP1 9.52e-26 Coagulation factor V (Activated protein C cofactor) [Cleaved into: Coagulation factor V heavy chain; Coagulation factor V light chain] Sus scrofa (Pig) blood circulation [GO:0008015]; blood coagulation [GO:0007596] GO:0005507; GO:0005576; GO:0007596; GO:0008015; GO:0031091 1199 XR_006397984.1 13 3 3 0 43 NA NA NA NA NA NA 1200 XM_029335938.2 41 0 27 17 20 Q2XWK0 8.48e-104 Synaptic vesicle 2-related protein (SV2-related protein) Xenopus laevis (African clawed frog) NA GO:0022857; GO:0030672 1201 XR_006395769.1 57 278 241 740 94 NA NA NA NA NA NA 1202 XM_044325590.1 66 11 22 42 39 Q96RW7 2.31e-36 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 1203 XM_044325590.1 66 11 22 42 39 Q96RW7 3.86e-27 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 1204 XM_029333174.2 0 4 0 18 0 P10079 7.56e-85 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 1205 XM_029333174.2 0 4 0 18 0 P10079 9.55e-84 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 1206 XM_029333174.2 0 4 0 18 0 P10079 1.47e-83 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 1207 XM_029333174.2 0 4 0 18 0 P10079 1.19e-81 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 1208 XM_029333174.2 0 4 0 18 0 P10079 4.34e-81 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 1209 XM_029333174.2 0 4 0 18 0 P10079 1.59e-80 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 1210 XM_029333174.2 0 4 0 18 0 P10079 1.78e-80 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 1211 XM_029333174.2 0 4 0 18 0 P10079 4.79e-80 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 1212 XM_029333174.2 0 4 0 18 0 P10079 5.18e-80 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 1213 XM_029333174.2 0 4 0 18 0 P10079 1.17e-79 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 1214 XM_029333174.2 0 4 0 18 0 P10079 2.96e-78 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 1215 XM_029333174.2 0 4 0 18 0 P10079 4.1e-76 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 1216 XM_029333174.2 0 4 0 18 0 P10079 8.31e-74 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 1217 XM_029333174.2 0 4 0 18 0 P10079 7.05e-47 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 1218 XR_006395121.1 22 11 24 12 40 NA NA NA NA NA NA 1219 XM_044314832.1 0 8 0 0 0 NA NA NA NA NA NA 1220 XM_044322197.1 23 0 42 3 6 NA NA NA NA NA NA 1221 XM_029348743.2 2290 1553 1434 1500 1369 A6QQX9 4.96e-30 Transmembrane protein 163 Bos taurus (Bovine) NA GO:0008270; GO:0016020; GO:0030672; GO:0031901 1222 XM_029345900.2 660 419 322 671 669 Q68DU8 4.86e-63 BTB/POZ domain-containing protein KCTD16 (Potassium channel tetramerization domain-containing protein 16) Homo sapiens (Human) protein homooligomerization [GO:0051260]; regulation of G protein-coupled receptor signaling pathway [GO:0008277] GO:0008277; GO:0042734; GO:0042995; GO:0043235; GO:0045211; GO:0051260 1223 XM_029332592.2 1808 1106 984 1389 1449 A1YF12 2.78e-37 Zinc finger protein 16 Gorilla gorilla gorilla (Western lowland gorilla) cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to sodium dodecyl sulfate [GO:0072707]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell cycle phase transition [GO:1901989]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of kinase activity [GO:0033674]; positive regulation of megakaryocyte differentiation [GO:0045654]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0005654; GO:0005730; GO:0006357; GO:0007049; GO:0008284; GO:0033674; GO:0043066; GO:0045648; GO:0045654; GO:0046872; GO:0051301; GO:0051781; GO:0072707; GO:1901989 1224 XM_029332592.2 1808 1106 984 1389 1449 A1YF12 1.4e-28 Zinc finger protein 16 Gorilla gorilla gorilla (Western lowland gorilla) cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to sodium dodecyl sulfate [GO:0072707]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell cycle phase transition [GO:1901989]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of kinase activity [GO:0033674]; positive regulation of megakaryocyte differentiation [GO:0045654]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0005654; GO:0005730; GO:0006357; GO:0007049; GO:0008284; GO:0033674; GO:0043066; GO:0045648; GO:0045654; GO:0046872; GO:0051301; GO:0051781; GO:0072707; GO:1901989 1225 XM_029332592.2 1808 1106 984 1389 1449 A1YF12 4.71e-27 Zinc finger protein 16 Gorilla gorilla gorilla (Western lowland gorilla) cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to sodium dodecyl sulfate [GO:0072707]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell cycle phase transition [GO:1901989]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of kinase activity [GO:0033674]; positive regulation of megakaryocyte differentiation [GO:0045654]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0005654; GO:0005730; GO:0006357; GO:0007049; GO:0008284; GO:0033674; GO:0043066; GO:0045648; GO:0045654; GO:0046872; GO:0051301; GO:0051781; GO:0072707; GO:1901989 1226 XM_029332592.2 1808 1106 984 1389 1449 A1YF12 7.11e-27 Zinc finger protein 16 Gorilla gorilla gorilla (Western lowland gorilla) cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to sodium dodecyl sulfate [GO:0072707]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell cycle phase transition [GO:1901989]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of kinase activity [GO:0033674]; positive regulation of megakaryocyte differentiation [GO:0045654]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0005654; GO:0005730; GO:0006357; GO:0007049; GO:0008284; GO:0033674; GO:0043066; GO:0045648; GO:0045654; GO:0046872; GO:0051301; GO:0051781; GO:0072707; GO:1901989 1227 XM_029332592.2 1808 1106 984 1389 1449 A1YF12 2.22e-26 Zinc finger protein 16 Gorilla gorilla gorilla (Western lowland gorilla) cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to sodium dodecyl sulfate [GO:0072707]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell cycle phase transition [GO:1901989]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of kinase activity [GO:0033674]; positive regulation of megakaryocyte differentiation [GO:0045654]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0005654; GO:0005730; GO:0006357; GO:0007049; GO:0008284; GO:0033674; GO:0043066; GO:0045648; GO:0045654; GO:0046872; GO:0051301; GO:0051781; GO:0072707; GO:1901989 1228 XM_029332592.2 1808 1106 984 1389 1449 A1YF12 8.49e-26 Zinc finger protein 16 Gorilla gorilla gorilla (Western lowland gorilla) cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to sodium dodecyl sulfate [GO:0072707]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell cycle phase transition [GO:1901989]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of kinase activity [GO:0033674]; positive regulation of megakaryocyte differentiation [GO:0045654]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0005654; GO:0005730; GO:0006357; GO:0007049; GO:0008284; GO:0033674; GO:0043066; GO:0045648; GO:0045654; GO:0046872; GO:0051301; GO:0051781; GO:0072707; GO:1901989 1229 XM_044308905.1 36 6 0 0 0 NA NA NA NA NA NA 1230 XM_029346337.2 152 4 122 112 189 E1BJS7 2.12e-121 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Bos taurus (Bovine) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA processing [GO:0035196]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; post-transcriptional regulation of gene expression [GO:0010608]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0010608; GO:0017148; GO:0021915; GO:0030371; GO:0035196; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 1231 XM_029331572.2 5119 7596 3453 5990 3109 Q2KID4 1.1e-92 Dynein axonemal light chain 1 Bos taurus (Bovine) outer dynein arm assembly [GO:0036158] GO:0005737; GO:0005874; GO:0030286; GO:0036158; GO:0042995; GO:0043014; GO:0045504 1232 XM_044325013.1 0 0 8 2 0 NA NA NA NA NA NA 1233 XM_029325613.2 2482 1842 1308 1170 800 Q9Z2V9 5.89e-38 Cyclin-I Mus musculus (Mouse) mitotic cell cycle phase transition [GO:0044772]; regulation of cell cycle [GO:0051726]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079] GO:0000079; GO:0000307; GO:0005634; GO:0005737; GO:0016538; GO:0044772; GO:0051726 1234 XM_044318592.1 382 347 442 324 796 Q9D6Y9 0 1,4-alpha-glucan-branching enzyme (EC 2.4.1.18) (Brancher enzyme) (Glycogen-branching enzyme) Mus musculus (Mouse) carbohydrate metabolic process [GO:0005975]; glycogen biosynthetic process [GO:0005978]; negative regulation of neuron apoptotic process [GO:0043524] GO:0003844; GO:0004553; GO:0005737; GO:0005829; GO:0005975; GO:0005978; GO:0030246; GO:0043169; GO:0043524; GO:0102752 1235 XM_044310858.1 411 296 420 195 214 Q7RTR2 5.69e-68 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 1236 XM_044310858.1 411 296 420 195 214 Q7RTR2 9.32e-64 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 1237 XM_044310858.1 411 296 420 195 214 Q7RTR2 1.22e-62 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 1238 XM_044310858.1 411 296 420 195 214 Q7RTR2 2.29e-55 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 1239 XM_044310858.1 411 296 420 195 214 Q7RTR2 8.64e-32 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 1240 XR_003823346.2 32 18 50 68 115 NA NA NA NA NA NA 1241 XM_029353629.2 0 0 0 0 165 P25931 1.44e-23 RYamide receptor (Neuropeptide Y-like receptor) (NPY-R) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218] GO:0001653; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0016020 1242 XM_044319578.1 19 8 4 8 44 NA NA NA NA NA NA 1243 XR_006391386.1 106 58 10 77 126 Q9WVK8 3.94e-92 Cholesterol 24-hydroxylase (CH24H) (EC 1.14.14.25) (Cholesterol 24-monooxygenase) (Cholesterol 24S-hydroxylase) (Cytochrome P450 46A1) Mus musculus (Mouse) cholesterol catabolic process [GO:0006707]; progesterone metabolic process [GO:0042448]; protein localization to membrane raft [GO:1903044]; regulation of long-term synaptic potentiation [GO:1900271]; xenobiotic metabolic process [GO:0006805] GO:0005506; GO:0005789; GO:0006707; GO:0006805; GO:0008395; GO:0020037; GO:0030425; GO:0033781; GO:0042448; GO:0062184; GO:0098793; GO:0098794; GO:1900271; GO:1903044 1244 XM_044309510.1 72 40 92 24 81 NA NA NA NA NA NA 1245 XM_044328315.1 0 0 0 0 12 NA NA NA NA NA NA 1246 XM_044324025.1 390 227 220 331 303 NA NA NA NA NA NA 1247 XM_029341748.2 348 326 345 374 430 Q6DF62 5.33e-84 Regucalcin (RC) (Gluconolactonase) (GNL) (EC 3.1.1.17) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cellular calcium ion homeostasis [GO:0006874]; L-ascorbic acid biosynthetic process [GO:0019853]; positive regulation of ATP-dependent activity [GO:0032781]; regulation of calcium-mediated signaling [GO:0050848] GO:0004341; GO:0005509; GO:0005634; GO:0005737; GO:0006874; GO:0008270; GO:0019853; GO:0030234; GO:0032781; GO:0050848 1248 XM_029330011.2 629 520 410 477 611 O70279 3.45e-85 Splicing factor ESS-2 homolog (ES2 protein) (Expressed sequence 2 embryonic lethal) Mus musculus (Mouse) mRNA processing [GO:0006397]; nervous system development [GO:0007399]; RNA splicing [GO:0008380] GO:0005634; GO:0006397; GO:0007399; GO:0008380; GO:0071013 1249 XM_044321795.1 16990 14576 6662 13616 8322 P79145 6.35e-33 cAMP-responsive element modulator Canis lupus familiaris (Dog) (Canis familiaris) regulation of transcription by RNA polymerase II [GO:0006357]; response to stimulus [GO:0050896] GO:0000978; GO:0000981; GO:0001227; GO:0005667; GO:0006357; GO:0050896; GO:1990589 1250 XR_003827137.2 20 11 2 10 5 NA NA NA NA NA NA 1251 XM_044322623.1 0 4 2 0 356 NA NA NA NA NA NA 1252 XR_006392488.1 389 634 248 29 184 G5E8K5 2.73e-35 Ankyrin-3 (ANK-3) (Ankyrin-G) Mus musculus (Mouse) anterograde axonal transport [GO:0008089]; axon development [GO:0061564]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; clustering of voltage-gated sodium channels [GO:0045162]; establishment of protein localization [GO:0045184]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in cell [GO:0032507]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of endocytosis [GO:0045806]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of action potential [GO:0045760]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; regulation of protein targeting [GO:1903533]; signal transduction [GO:0007165]; synapse organization [GO:0050808] GO:0000281; GO:0005200; GO:0005737; GO:0005764; GO:0005886; GO:0005923; GO:0007009; GO:0007165; GO:0007409; GO:0007411; GO:0007528; GO:0008089; GO:0008092; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014069; GO:0014704; GO:0014731; GO:0016020; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030424; GO:0030425; GO:0030507; GO:0030674; GO:0030951; GO:0031594; GO:0032507; GO:0033268; GO:0033270; GO:0034112; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045162; GO:0045184; GO:0045202; GO:0045211; GO:0045296; GO:0045760; GO:0045806; GO:0045838; GO:0050808; GO:0061564; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:0140031; GO:1900827; GO:1901224; GO:1902260; GO:1903533; GO:1904115; GO:2000651; GO:2001259 1253 XR_006392488.1 389 634 248 29 184 G5E8K5 2.73e-35 Ankyrin-3 (ANK-3) (Ankyrin-G) Mus musculus (Mouse) anterograde axonal transport [GO:0008089]; axon development [GO:0061564]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; clustering of voltage-gated sodium channels [GO:0045162]; establishment of protein localization [GO:0045184]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in cell [GO:0032507]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of endocytosis [GO:0045806]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of action potential [GO:0045760]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; regulation of protein targeting [GO:1903533]; signal transduction [GO:0007165]; synapse organization [GO:0050808] GO:0000281; GO:0005200; GO:0005737; GO:0005764; GO:0005886; GO:0005923; GO:0007009; GO:0007165; GO:0007409; GO:0007411; GO:0007528; GO:0008089; GO:0008092; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014069; GO:0014704; GO:0014731; GO:0016020; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030424; GO:0030425; GO:0030507; GO:0030674; GO:0030951; GO:0031594; GO:0032507; GO:0033268; GO:0033270; GO:0034112; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045162; GO:0045184; GO:0045202; GO:0045211; GO:0045296; GO:0045760; GO:0045806; GO:0045838; GO:0050808; GO:0061564; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:0140031; GO:1900827; GO:1901224; GO:1902260; GO:1903533; GO:1904115; GO:2000651; GO:2001259 1254 XR_006392488.1 389 634 248 29 184 G5E8K5 4.53e-22 Ankyrin-3 (ANK-3) (Ankyrin-G) Mus musculus (Mouse) anterograde axonal transport [GO:0008089]; axon development [GO:0061564]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; clustering of voltage-gated sodium channels [GO:0045162]; establishment of protein localization [GO:0045184]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in cell [GO:0032507]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of endocytosis [GO:0045806]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of action potential [GO:0045760]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; regulation of protein targeting [GO:1903533]; signal transduction [GO:0007165]; synapse organization [GO:0050808] GO:0000281; GO:0005200; GO:0005737; GO:0005764; GO:0005886; GO:0005923; GO:0007009; GO:0007165; GO:0007409; GO:0007411; GO:0007528; GO:0008089; GO:0008092; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014069; GO:0014704; GO:0014731; GO:0016020; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030424; GO:0030425; GO:0030507; GO:0030674; GO:0030951; GO:0031594; GO:0032507; GO:0033268; GO:0033270; GO:0034112; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045162; GO:0045184; GO:0045202; GO:0045211; GO:0045296; GO:0045760; GO:0045806; GO:0045838; GO:0050808; GO:0061564; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:0140031; GO:1900827; GO:1901224; GO:1902260; GO:1903533; GO:1904115; GO:2000651; GO:2001259 1255 XR_006392488.1 389 634 248 29 184 G5E8K5 4.38e-21 Ankyrin-3 (ANK-3) (Ankyrin-G) Mus musculus (Mouse) anterograde axonal transport [GO:0008089]; axon development [GO:0061564]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; clustering of voltage-gated sodium channels [GO:0045162]; establishment of protein localization [GO:0045184]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in cell [GO:0032507]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of endocytosis [GO:0045806]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of action potential [GO:0045760]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; regulation of protein targeting [GO:1903533]; signal transduction [GO:0007165]; synapse organization [GO:0050808] GO:0000281; GO:0005200; GO:0005737; GO:0005764; GO:0005886; GO:0005923; GO:0007009; GO:0007165; GO:0007409; GO:0007411; GO:0007528; GO:0008089; GO:0008092; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014069; GO:0014704; GO:0014731; GO:0016020; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030424; GO:0030425; GO:0030507; GO:0030674; GO:0030951; GO:0031594; GO:0032507; GO:0033268; GO:0033270; GO:0034112; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045162; GO:0045184; GO:0045202; GO:0045211; GO:0045296; GO:0045760; GO:0045806; GO:0045838; GO:0050808; GO:0061564; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:0140031; GO:1900827; GO:1901224; GO:1902260; GO:1903533; GO:1904115; GO:2000651; GO:2001259 1256 XM_029327549.2 9 3 12 0 3 NA NA NA NA NA NA 1257 XM_029338502.2 337 164 83 124 283 NA NA NA NA NA NA 1258 XM_044327158.1 79 13 74 104 13 NA NA NA NA NA NA 1259 XM_029342596.2 677 416 131 374 718 Q6DKK2 8.23e-23 Tetratricopeptide repeat protein 19, mitochondrial (TPR repeat protein 19) Homo sapiens (Human) mitochondrial respiratory chain complex III assembly [GO:0034551]; mitotic cytokinesis [GO:0000281] GO:0000281; GO:0005739; GO:0005743; GO:0005813; GO:0030496; GO:0034551; GO:0070469 1260 XM_044315892.1 2800 1226 1443 3607 3153 B3EWY9 0 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 1261 XM_044315892.1 2800 1226 1443 3607 3153 B3EWY9 0 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 1262 XM_044315892.1 2800 1226 1443 3607 3153 B3EWY9 4.03e-41 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 1263 XM_044315892.1 2800 1226 1443 3607 3153 B3EWY9 4.77e-37 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 1264 XM_044315892.1 2800 1226 1443 3607 3153 B3EWY9 6.45e-37 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 1265 XM_044315892.1 2800 1226 1443 3607 3153 B3EWY9 3.25e-36 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 1266 XM_044315892.1 2800 1226 1443 3607 3153 B3EWY9 1.75e-35 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 1267 XM_044315892.1 2800 1226 1443 3607 3153 B3EWY9 4.66e-35 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 1268 XM_044315892.1 2800 1226 1443 3607 3153 B3EWY9 1.5e-34 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 1269 XM_044315892.1 2800 1226 1443 3607 3153 B3EWY9 4.23e-34 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 1270 XM_044315892.1 2800 1226 1443 3607 3153 B3EWY9 8.87e-34 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 1271 XM_044315892.1 2800 1226 1443 3607 3153 B3EWY9 9.02e-34 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 1272 XM_044315892.1 2800 1226 1443 3607 3153 B3EWY9 6.42e-33 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 1273 XM_044315892.1 2800 1226 1443 3607 3153 B3EWY9 4.19e-32 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 1274 XM_044315892.1 2800 1226 1443 3607 3153 B3EWY9 6.33e-32 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 1275 XM_044315892.1 2800 1226 1443 3607 3153 B3EWY9 1.17e-31 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 1276 XM_044315892.1 2800 1226 1443 3607 3153 B3EWY9 2.42e-30 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 1277 XM_044315892.1 2800 1226 1443 3607 3153 B3EWY9 2.82e-30 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 1278 XM_044315892.1 2800 1226 1443 3607 3153 B3EWY9 2.9e-29 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 1279 XM_044315892.1 2800 1226 1443 3607 3153 B3EWY9 8.42e-27 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 1280 XM_029323708.2 195 103 101 103 65 Q68ED7 3.03e-30 CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1 homolog) (Transducer of regulated cAMP response element-binding protein 1) (TORC-1) (Transducer of CREB protein 1) Mus musculus (Mouse) energy homeostasis [GO:0097009]; entrainment of circadian clock by photoperiod [GO:0043153]; memory [GO:0007613]; negative regulation of membrane hyperpolarization [GO:1902631]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of dendrite development [GO:1900006]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of transcription by RNA polymerase II [GO:0045944]; postsynapse to nucleus signaling pathway [GO:0099527]; protein homotetramerization [GO:0051289]; rhythmic process [GO:0048511] GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0007613; GO:0008140; GO:0014069; GO:0016604; GO:0030425; GO:0032793; GO:0043025; GO:0043153; GO:0045202; GO:0045944; GO:0048511; GO:0051289; GO:0097009; GO:0098978; GO:0099527; GO:1900006; GO:1900273; GO:1902631 1281 XM_044324582.1 0 0 14 0 25 NA NA NA NA NA NA 1282 XM_044326151.1 20 18 6 11 25 NA NA NA NA NA NA 1283 XM_044322738.1 0 31 0 0 0 NA NA NA NA NA NA 1284 XM_029329754.2 23 0 24 0 2 NA NA NA NA NA NA 1285 XM_044323174.1 44 54 36 332 205 NA NA NA NA NA NA 1286 XM_029338125.2 56 35 24 0 44 P08510 7.07e-87 Potassium voltage-gated channel protein Shaker (Protein minisleep) Drosophila melanogaster (Fruit fly) action potential [GO:0001508]; axon extension [GO:0048675]; behavioral response to ether [GO:0048150]; cellular response to dopamine [GO:1903351]; courtship behavior [GO:0007619]; detection of visible light [GO:0009584]; larval locomotory behavior [GO:0008345]; learning or memory [GO:0007611]; mating behavior, sex discrimination [GO:0048047]; positive regulation of circadian sleep/wake cycle, sleep [GO:0045938]; positive regulation of membrane potential [GO:0045838]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; proboscis extension reflex [GO:0007637]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; regulation of ion transmembrane transport [GO:0034765]; regulation of synaptic activity [GO:0060025]; sensory perception of taste [GO:0050909]; sleep [GO:0030431] GO:0001508; GO:0005249; GO:0005251; GO:0006813; GO:0007611; GO:0007619; GO:0007637; GO:0008076; GO:0008345; GO:0009584; GO:0016020; GO:0022843; GO:0030431; GO:0034765; GO:0045187; GO:0045838; GO:0045938; GO:0048047; GO:0048150; GO:0048675; GO:0050909; GO:0051260; GO:0060025; GO:0071805; GO:1903351 1287 XM_044308329.1 21 270 27 0 0 NA NA NA NA NA NA 1288 XM_029348520.2 50 2 5 30 30 NA NA NA NA NA NA 1289 XR_006392522.1 109 47 87 53 8 NA NA NA NA NA NA 1290 XM_029331704.2 920 1168 770 994 1410 Q6NX31 0 DNA replication licensing factor mcm7 (EC 3.6.4.12) (CDC47 homolog) (Minichromosome maintenance protein 7) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell cycle [GO:0007049]; DNA replication initiation [GO:0006270]; DNA unwinding involved in DNA replication [GO:0006268]; regulation of DNA-templated DNA replication initiation [GO:0030174] GO:0000785; GO:0003677; GO:0003678; GO:0005524; GO:0006268; GO:0006270; GO:0007049; GO:0016887; GO:0030174; GO:0042555; GO:0046872; GO:0071162 1291 XM_029343891.2 9 16 20 14 15 NA NA NA NA NA NA 1292 XR_006396403.1 1487 1819 1027 1771 2551 NA NA NA NA NA NA 1293 XM_029346049.2 1943 2616 1660 2281 2399 NA NA NA NA NA NA 1294 XM_044322514.1 14 0 6 49 8 NA NA NA NA NA NA 1295 XM_044311205.1 14 0 0 0 0 NA NA NA NA NA NA 1296 XM_044316592.1 5 8 0 7 37 NA NA NA NA NA NA 1297 XM_029357296.2 120 93 53 137 92 NA NA NA NA NA NA 1298 XM_029338461.2 199 129 127 174 170 O43435 1.62e-91 T-box transcription factor TBX1 (T-box protein 1) (Testis-specific T-box protein) Homo sapiens (Human) angiogenesis [GO:0001525]; anterior/posterior pattern specification [GO:0009952]; aorta morphogenesis [GO:0035909]; artery morphogenesis [GO:0048844]; blood vessel development [GO:0001568]; blood vessel morphogenesis [GO:0048514]; cell fate specification [GO:0001708]; cell population proliferation [GO:0008283]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to retinoic acid [GO:0071300]; cochlea morphogenesis [GO:0090103]; coronary artery morphogenesis [GO:0060982]; determination of left/right symmetry [GO:0007368]; ear morphogenesis [GO:0042471]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic viscerocranium morphogenesis [GO:0048703]; enamel mineralization [GO:0070166]; epithelial cell differentiation [GO:0030855]; face morphogenesis [GO:0060325]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; inner ear morphogenesis [GO:0042472]; lymph vessel development [GO:0001945]; mesenchymal cell apoptotic process [GO:0097152]; mesoderm development [GO:0007498]; middle ear morphogenesis [GO:0042474]; muscle cell fate commitment [GO:0042693]; muscle organ development [GO:0007517]; muscle organ morphogenesis [GO:0048644]; muscle tissue morphogenesis [GO:0060415]; negative regulation of cell differentiation [GO:0045596]; negative regulation of mesenchymal cell apoptotic process [GO:2001054]; neural crest cell migration [GO:0001755]; odontogenesis of dentin-containing tooth [GO:0042475]; outer ear morphogenesis [GO:0042473]; outflow tract morphogenesis [GO:0003151]; outflow tract septum morphogenesis [GO:0003148]; parathyroid gland development [GO:0060017]; pattern specification process [GO:0007389]; pharyngeal system development [GO:0060037]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of tongue muscle cell differentiation [GO:2001037]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of animal organ morphogenesis [GO:2000027]; regulation of transcription by RNA polymerase II [GO:0006357]; retinoic acid receptor signaling pathway [GO:0048384]; semicircular canal morphogenesis [GO:0048752]; sensory perception of sound [GO:0007605]; social behavior [GO:0035176]; soft palate development [GO:0060023]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; tongue morphogenesis [GO:0043587]; vagus nerve morphogenesis [GO:0021644] GO:0000785; GO:0000978; GO:0000981; GO:0001525; GO:0001568; GO:0001708; GO:0001755; GO:0001934; GO:0001945; GO:0002053; GO:0003007; GO:0003148; GO:0003151; GO:0003677; GO:0005634; GO:0006357; GO:0007368; GO:0007389; GO:0007498; GO:0007507; GO:0007517; GO:0007605; GO:0008283; GO:0008284; GO:0009952; GO:0021644; GO:0030855; GO:0030878; GO:0035176; GO:0035909; GO:0042471; GO:0042472; GO:0042473; GO:0042474; GO:0042475; GO:0042693; GO:0042803; GO:0043410; GO:0043565; GO:0043587; GO:0044344; GO:0045596; GO:0045893; GO:0045944; GO:0046983; GO:0048384; GO:0048514; GO:0048538; GO:0048644; GO:0048701; GO:0048703; GO:0048752; GO:0048844; GO:0050679; GO:0060017; GO:0060023; GO:0060037; GO:0060325; GO:0060415; GO:0060982; GO:0070166; GO:0071300; GO:0090103; GO:0097152; GO:1990837; GO:2000027; GO:2001037; GO:2001054 1299 XM_044321916.1 0 18 0 89 209 Q9ESJ0 0 Exportin-4 (Exp4) Mus musculus (Mouse) positive regulation of protein export from nucleus [GO:0046827]; protein export from nucleus [GO:0006611] GO:0005049; GO:0005643; GO:0005654; GO:0005737; GO:0005829; GO:0006611; GO:0046827 1300 XM_044322989.1 196 431 343 879 74 Q7RTR2 2.33e-72 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 1301 XM_044322989.1 196 431 343 879 74 Q7RTR2 7.31e-72 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 1302 XM_044322989.1 196 431 343 879 74 Q7RTR2 2.82e-67 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 1303 XM_044322989.1 196 431 343 879 74 Q7RTR2 1.4e-27 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 1304 XM_029324100.2 0 8 2 6 0 NA NA NA NA NA NA 1305 XR_006395669.1 69 40 1 26 48 NA NA NA NA NA NA 1306 XM_044326325.1 147 80 88 103 148 NA NA NA NA NA NA 1307 XM_044322880.1 8563 8586 7186 12159 4634 P15882 2.04e-172 N-chimaerin (A-chimaerin) (Alpha-chimerin) (N-chimerin) (NC) (Rho GTPase-activating protein 2) Homo sapiens (Human) ephrin receptor signaling pathway [GO:0048013]; motor neuron axon guidance [GO:0008045]; positive regulation of GTPase activity [GO:0043547]; regulation of axonogenesis [GO:0050770]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056] GO:0005096; GO:0005829; GO:0008045; GO:0043087; GO:0043547; GO:0046872; GO:0046875; GO:0048013; GO:0050770; GO:0051056 1308 XM_044317907.1 551 403 330 553 413 NA NA NA NA NA NA 1309 XM_029340317.2 623 89 372 402 256 Q13322 2.71e-64 Growth factor receptor-bound protein 10 (GRB10 adapter protein) (Insulin receptor-binding protein Grb-IR) Homo sapiens (Human) ERK1 and ERK2 cascade [GO:0070371]; gene expression [GO:0010467]; insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009]; negative regulation of glucose import [GO:0046325]; negative regulation of glycogen biosynthetic process [GO:0045719]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of phosphorylation [GO:0042326]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of phosphorylation [GO:0042327]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; response to insulin [GO:0032868]; vascular associated smooth muscle cell migration [GO:1904738] GO:0005158; GO:0005737; GO:0005829; GO:0005886; GO:0008286; GO:0010467; GO:0030159; GO:0030178; GO:0030949; GO:0032868; GO:0032991; GO:0042326; GO:0042327; GO:0042802; GO:0045719; GO:0046325; GO:0046627; GO:0048009; GO:0070371; GO:0120162; GO:1904738 1310 XM_029334179.2 0 27 0 32 2 NA NA NA NA NA NA 1311 XM_029357520.2 17 3 0 1 0 Q9U6Y6 5.56e-110 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 1312 XM_029325619.2 1518 1437 1231 1464 1721 A2BGM5 2.37e-40 Forkhead box protein N4 Danio rerio (Zebrafish) (Brachydanio rerio) amacrine cell differentiation [GO:0035881]; atrioventricular canal development [GO:0036302]; heart looping [GO:0001947]; heart valve development [GO:0003170]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of heart contraction [GO:0008016]; retina layer formation [GO:0010842]; ventral spinal cord interneuron fate commitment [GO:0060579] GO:0000981; GO:0000987; GO:0001947; GO:0003170; GO:0003682; GO:0003700; GO:0005634; GO:0006355; GO:0008016; GO:0010842; GO:0035881; GO:0036302; GO:0043565; GO:0045893; GO:0045944; GO:0060579 1313 XM_044323456.1 164 22 39 166 65 NA NA NA NA NA NA 1314 XM_044306802.1 912 713 755 1443 1171 O15033 0 Apoptosis-resistant E3 ubiquitin protein ligase 1 (EC 2.3.2.26) (Apoptosis-resistant HECT-type E3 ubiquitin transferase 1) Homo sapiens (Human) apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K11-linked ubiquitination [GO:0070979]; protein K33-linked ubiquitination [GO:1990390]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of inflammatory response [GO:0050727]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000209; GO:0004842; GO:0005737; GO:0005829; GO:0006511; GO:0006915; GO:0016567; GO:0043066; GO:0043161; GO:0050727; GO:0061630; GO:0070979; GO:1990390 1315 XM_044319777.1 1764 462 641 1920 1085 Q26636 4.68e-131 Cathepsin L (EC 3.4.22.15) [Cleaved into: Cathepsin L heavy chain; Cathepsin L light chain] Sarcophaga peregrina (Flesh fly) (Boettcherisca peregrina) cell differentiation [GO:0030154]; proteolysis [GO:0006508] GO:0004197; GO:0005764; GO:0006508; GO:0030154 1316 XM_044314542.1 24614 23801 12930 15820 12006 NA NA NA NA NA NA 1317 XM_044325032.1 1169 1046 1078 1267 2464 NA NA NA NA NA NA 1318 XR_003825594.2 22 4 4 2 97 NA NA NA NA NA NA 1319 XM_044319356.1 2 8 1 6 5 NA NA NA NA NA NA 1320 XR_006397870.1 117 43 16 146 72 NA NA NA NA NA NA 1321 XM_029342784.2 74 85 52 246 116 NA NA NA NA NA NA 1322 XR_006396785.1 1435 1145 739 1475 1062 P56698 0 Probable voltage-dependent N-type calcium channel subunit alpha-1B (DOE-4) (Voltage-gated calcium channel subunit alpha Cav2.2) Diplobatis ommata (Ocellated electric ray) (Discopyge ommata) regulation of ion transmembrane transport [GO:0034765] GO:0005245; GO:0005509; GO:0005891; GO:0034765 1323 XR_006396785.1 1435 1145 739 1475 1062 P56698 3.52e-153 Probable voltage-dependent N-type calcium channel subunit alpha-1B (DOE-4) (Voltage-gated calcium channel subunit alpha Cav2.2) Diplobatis ommata (Ocellated electric ray) (Discopyge ommata) regulation of ion transmembrane transport [GO:0034765] GO:0005245; GO:0005509; GO:0005891; GO:0034765 1324 XR_006396785.1 1435 1145 739 1475 1062 P56698 3.88e-29 Probable voltage-dependent N-type calcium channel subunit alpha-1B (DOE-4) (Voltage-gated calcium channel subunit alpha Cav2.2) Diplobatis ommata (Ocellated electric ray) (Discopyge ommata) regulation of ion transmembrane transport [GO:0034765] GO:0005245; GO:0005509; GO:0005891; GO:0034765 1325 XM_044316526.1 5 10 7 5 15 NA NA NA NA NA NA 1326 XM_044316106.1 179 95 91 47 63 Q7RTR2 1.91e-41 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 1327 XM_044316106.1 179 95 91 47 63 Q7RTR2 4.26e-40 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 1328 XM_044316106.1 179 95 91 47 63 Q7RTR2 5.34e-37 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 1329 XM_044316106.1 179 95 91 47 63 Q7RTR2 1.92e-34 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 1330 XM_044316106.1 179 95 91 47 63 Q7RTR2 3.18e-33 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 1331 XM_029334974.2 410 251 245 452 299 NA NA NA NA NA NA 1332 XM_029348414.2 115 64 91 43 138 Q3ZCH9 5.97e-96 Haloacid dehalogenase-like hydrolase domain-containing protein 2 Bos taurus (Bovine) dephosphorylation [GO:0016311] GO:0016311; GO:0016791; GO:0019899; GO:0046872 1333 XM_029350594.2 0 9 0 0 5 Q4KM95 7.2e-43 Leucine-rich repeat-containing protein 42 Rattus norvegicus (Rat) NA NA 1334 XM_029348041.2 1574 655 1011 1109 1005 NA NA NA NA NA NA 1335 XM_044320210.1 0 0 0 0 189 NA NA NA NA NA NA 1336 XM_044309781.1 19 2 21 23 57 NA NA NA NA NA NA 1337 XM_044307148.1 196 651 186 234 205 Q2HJG7 6.89e-37 Protein Churchill Bos taurus (Bovine) fibroblast growth factor receptor signaling pathway [GO:0008543]; positive regulation of DNA-templated transcription [GO:0045893] GO:0008270; GO:0008543; GO:0045893 1338 XR_006392817.1 357 122 7 434 513 NA NA NA NA NA NA 1339 XR_006395244.1 0 0 0 9 0 NA NA NA NA NA NA 1340 XM_029349292.2 226 613 27 104 157 NA NA NA NA NA NA 1341 XR_006395169.1 9 62 128 18 55 NA NA NA NA NA NA 1342 XM_044320381.1 0 1218 429 76 555 Q14517 0 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 1343 XM_044320381.1 0 1218 429 76 555 Q14517 6.6e-55 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 1344 XM_044320381.1 0 1218 429 76 555 Q14517 1.09e-34 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 1345 XM_029331540.2 860 924 795 902 1002 NA NA NA NA NA NA 1346 XM_044307688.1 106 6 24 32 155 NA NA NA NA NA NA 1347 XM_029337505.2 307 228 277 184 515 NA NA NA NA NA NA 1348 XM_029350548.2 8 13 15 13 4 NA NA NA NA NA NA 1349 XM_044320276.1 12647 35676 13881 8505 5518 NA NA NA NA NA NA 1350 XM_044319135.1 0 0 0 0 111 NA NA NA NA NA NA 1351 XM_044325354.1 56 20 95 16 81 P48733 2.77e-27 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Bos taurus (Bovine) antibacterial innate immune response [GO:0140367]; defense response to Gram-negative bacterium [GO:0050829] GO:0000922; GO:0005201; GO:0005509; GO:0005576; GO:0005929; GO:0016020; GO:0016323; GO:0016324; GO:0031012; GO:0050829; GO:0060170; GO:0140367 1352 XM_029342987.2 154 93 0 175 100 Q9JID6 0 Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3) (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain acyl-CoA synthetase 1) (LACS 1) (Palmitoyl-CoA ligase) (Phytanate--CoA ligase) (EC 6.2.1.24) Cavia porcellus (Guinea pig) long-chain fatty acid metabolic process [GO:0001676]; very long-chain fatty acid metabolic process [GO:0000038] GO:0000038; GO:0001676; GO:0004467; GO:0005524; GO:0005741; GO:0005778; GO:0005783; GO:0005789; GO:0047676; GO:0050197; GO:0070251 1353 XM_029329505.2 662 263 137 432 298 P70102 7.7e-33 Eukaryotic translation elongation factor 1 epsilon-1 (Elongation factor p18) (Multisynthase complex auxiliary component p18) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) negative regulation of cell population proliferation [GO:0008285]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043517]; translation [GO:0006412] GO:0005634; GO:0005737; GO:0006412; GO:0008285; GO:0017101; GO:0043065; GO:0043517 1354 XM_029331768.2 9335 9571 4681 12747 11063 Q90593 0 Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein) Gallus gallus (Chicken) cellular response to glucose starvation [GO:0042149]; cellular response to interleukin-4 [GO:0071353]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; positive regulation of cell migration [GO:0030335]; positive regulation of protein ubiquitination [GO:0031398]; post-translational protein targeting to membrane, translocation [GO:0031204]; protein refolding [GO:0042026]; toxin transport [GO:1901998]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0005524; GO:0005634; GO:0005737; GO:0005739; GO:0005788; GO:0005789; GO:0005793; GO:0005829; GO:0005886; GO:0006983; GO:0008180; GO:0009986; GO:0016020; GO:0016887; GO:0019904; GO:0021589; GO:0021680; GO:0030335; GO:0030433; GO:0030496; GO:0030512; GO:0030968; GO:0031072; GO:0031204; GO:0031333; GO:0031398; GO:0031625; GO:0034620; GO:0034663; GO:0035437; GO:0042026; GO:0042149; GO:0042470; GO:0043022; GO:0043066; GO:0044183; GO:0051082; GO:0051085; GO:0051787; GO:0071353; GO:0140662; GO:1901998; GO:1903895 1355 XR_006394325.1 63 6 68 82 60 NA NA NA NA NA NA 1356 XM_029331111.2 200 204 166 330 503 Q8TB52 9.59e-59 F-box only protein 30 Homo sapiens (Human) NA GO:0005829; GO:0008270; GO:0061630 1357 XM_029331111.2 200 204 166 330 503 Q8TB52 3.02e-25 F-box only protein 30 Homo sapiens (Human) NA GO:0005829; GO:0008270; GO:0061630 1358 XM_029353303.2 0 3 7 13 0 NA NA NA NA NA NA 1359 XM_044311448.1 7 0 0 0 0 NA NA NA NA NA NA 1360 XM_029338545.2 316 357 45 249 457 P55039 0 Developmentally-regulated GTP-binding protein 2 (DRG-2) (Translation factor GTPase DRG2) (TRAFAC GTPase DRG2) (EC 3.6.5.-) Homo sapiens (Human) cytoplasmic translation [GO:0002181]; signal transduction [GO:0007165] GO:0002181; GO:0003723; GO:0003924; GO:0005525; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0007165; GO:0016020; GO:0043231; GO:0046872 1361 XM_044308527.1 16 11 4 35 2 NA NA NA NA NA NA 1362 XM_044319490.1 2 0 19 20 31 NA NA NA NA NA NA 1363 XM_029345248.2 834 1821 918 1340 899 NA NA NA NA NA NA 1364 XM_044307970.1 12 2 0 0 2 NA NA NA NA NA NA 1365 XM_029344879.2 218 0 23 0 156 O88413 4.82e-135 Tubby-related protein 3 (Tubby-like protein 3) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; bone development [GO:0060348]; brain development [GO:0007420]; bronchus morphogenesis [GO:0060434]; central nervous system neuron differentiation [GO:0021953]; dorsal/ventral neural tube patterning [GO:0021904]; embryonic camera-type eye development [GO:0031076]; embryonic digit morphogenesis [GO:0042733]; embryonic neurocranium morphogenesis [GO:0048702]; ganglion development [GO:0061548]; limb development [GO:0060173]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:1901621]; negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning [GO:0021914]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; neural tube formation [GO:0001841]; protein localization to cilium [GO:0061512]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; regulation of smoothened signaling pathway [GO:0008589]; smoothened signaling pathway [GO:0007224]; smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] GO:0001664; GO:0001841; GO:0001843; GO:0005576; GO:0005634; GO:0005654; GO:0005730; GO:0005886; GO:0005929; GO:0005930; GO:0007224; GO:0007420; GO:0008277; GO:0008589; GO:0009952; GO:0019899; GO:0021904; GO:0021914; GO:0021915; GO:0021953; GO:0031076; GO:0035091; GO:0042733; GO:0044877; GO:0045879; GO:0048702; GO:0060173; GO:0060348; GO:0060434; GO:0060831; GO:0061512; GO:0061548; GO:0097546; GO:0097731; GO:0120160; GO:1901621 1366 XM_029345889.2 973 682 422 822 699 A7SNN5 0 Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) Nematostella vectensis (Starlet sea anemone) mitotic cell cycle [GO:0000278]; protein phosphorylation [GO:0006468]; regulation of cytokinesis [GO:0032465] GO:0000278; GO:0000922; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005814; GO:0006468; GO:0032465; GO:0106310 1367 XM_029338251.2 140 137 141 192 166 P22127 1.03e-85 Ras-related protein Rab-10 (ORA1) Diplobatis ommata (Ocellated electric ray) (Discopyge ommata) axonogenesis [GO:0007409]; cellular response to insulin stimulus [GO:0032869]; endoplasmic reticulum tubular network organization [GO:0071786]; endosomal transport [GO:0016197]; establishment of neuroblast polarity [GO:0045200]; establishment of protein localization to endoplasmic reticulum membrane [GO:0097051]; Golgi to plasma membrane protein transport [GO:0043001]; Golgi to plasma membrane transport [GO:0006893]; polarized epithelial cell differentiation [GO:0030859]; protein localization to basolateral plasma membrane [GO:1903361]; protein localization to plasma membrane [GO:0072659]; vesicle-mediated transport [GO:0016192] GO:0003924; GO:0005525; GO:0005768; GO:0005789; GO:0005794; GO:0005802; GO:0005929; GO:0006893; GO:0007409; GO:0016192; GO:0016197; GO:0019003; GO:0030670; GO:0030859; GO:0032593; GO:0032869; GO:0043001; GO:0045200; GO:0055037; GO:0055038; GO:0071782; GO:0071786; GO:0072659; GO:0097051; GO:1903361 1368 XM_044316848.1 4 41 29 58 68 NA NA NA NA NA NA 1369 XM_044318407.1 14 7 20 7 6 NA NA NA NA NA NA 1370 XR_006393598.1 97 56 32 17 2 NA NA NA NA NA NA 1371 XM_029340513.2 170 52 95 112 81 P35406 2.39e-31 D(1) dopamine receptor (Dopamine D1 receptor) Carassius auratus (Goldfish) regulation of biological quality [GO:0065008] GO:0004930; GO:0005886; GO:0065008 1372 XM_029339591.2 4 0 4 9 8 NA NA NA NA NA NA 1373 XM_029326544.2 32 2 14 0 0 Q69Z28 5.29e-158 A disintegrin and metalloproteinase with thrombospondin motifs 16 (ADAM-TS 16) (ADAM-TS16) (ADAMTS-16) (EC 3.4.24.-) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; extracellular matrix organization [GO:0030198]; male gamete generation [GO:0048232]; proteolysis [GO:0006508]; regulation of cilium assembly [GO:1902017]; regulation of systemic arterial blood pressure [GO:0003073] GO:0001658; GO:0003073; GO:0004222; GO:0005576; GO:0006508; GO:0030198; GO:0031012; GO:0046872; GO:0048232; GO:1902017 1374 XM_029339305.2 259 66 12 147 94 Q94BV5 3.16e-58 Flavin-containing monooxygenase FMO GS-OX-like 4 (EC 1.8.-.-) (Flavin-monooxygenase glucosinolate S-oxygenase-like 4) Arabidopsis thaliana (Mouse-ear cress) NA GO:0000325; GO:0004499; GO:0050660; GO:0050661 1375 XM_029345875.2 83 0 101 49 91 Q9I9K7 2.26e-115 T-box transcription factor TBX20 (T-box protein 20) (H15-related T-box transcription factor hrT) Danio rerio (Zebrafish) (Brachydanio rerio) angiogenesis [GO:0001525]; blood vessel development [GO:0001568]; cardiac muscle cell proliferation [GO:0060038]; cell fate specification [GO:0001708]; cloaca development [GO:0035844]; embryonic heart tube development [GO:0035050]; embryonic hemopoiesis [GO:0035162]; heart development [GO:0007507]; heart looping [GO:0001947]; heart rudiment development [GO:0003313]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of transcription by RNA polymerase II [GO:0006357]; vasculogenesis [GO:0001570] GO:0000978; GO:0000981; GO:0001525; GO:0001568; GO:0001570; GO:0001708; GO:0001947; GO:0003313; GO:0005634; GO:0006357; GO:0007507; GO:0035050; GO:0035162; GO:0035844; GO:0045892; GO:0045893; GO:0060038; GO:0060043 1376 XM_029328690.2 1044 1287 462 727 316 Q96DH6 2.73e-79 RNA-binding protein Musashi homolog 2 (Musashi-2) Homo sapiens (Human) central nervous system development [GO:0007417]; regulation of translation [GO:0006417]; stem cell development [GO:0048864] GO:0003723; GO:0003729; GO:0005737; GO:0005829; GO:0005844; GO:0006417; GO:0007417; GO:0008266; GO:0042802; GO:0043231; GO:0048864 1377 XM_044311984.1 0 11 16 6 24 NA NA NA NA NA NA 1378 XM_044309305.1 0 0 1 0 26 NA NA NA NA NA NA 1379 XM_029330678.2 4271 3403 2213 6304 3224 Q13951 1.19e-55 Core-binding factor subunit beta (CBF-beta) (Polyomavirus enhancer-binding protein 2 beta subunit) (PEA2-beta) (PEBP2-beta) (SL3-3 enhancer factor 1 subunit beta) (SL3/AKV core-binding factor beta subunit) Homo sapiens (Human) cell maturation [GO:0048469]; definitive hemopoiesis [GO:0060216]; lymphocyte differentiation [GO:0030098]; myeloid cell differentiation [GO:0030099]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of transcription by RNA polymerase II [GO:0000122]; osteoblast differentiation [GO:0001649]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein polyubiquitination [GO:0000209]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366] GO:0000122; GO:0000209; GO:0001649; GO:0003713; GO:0005654; GO:0006357; GO:0006366; GO:0016020; GO:0016513; GO:0030098; GO:0030099; GO:0043371; GO:0043378; GO:0043565; GO:0045944; GO:0048469; GO:0060216 1380 XM_029356776.2 86 5 79 9 198 Q02361 2.88e-24 Fork head domain-containing protein FD3 Drosophila melanogaster (Fruit fly) anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0009653; GO:0030154 1381 XM_044312835.1 0 0 381 312 0 Q6PD24 1.66e-162 Ankyrin repeat domain-containing protein 13D Mus musculus (Mouse) negative regulation of receptor internalization [GO:0002091] GO:0002091; GO:0005737; GO:0005770; GO:0005886; GO:0048471; GO:0140036 1382 XM_044313685.1 0 0 29 3 12 NA NA NA NA NA NA 1383 XM_044310444.1 263 95 171 230 142 NA NA NA NA NA NA 1384 XM_044327970.1 183 54 77 218 191 NA NA NA NA NA NA 1385 XM_029328563.2 4236 4949 3639 5226 5583 Q3ZBD7 0 Glucose-6-phosphate isomerase (GPI) (EC 5.3.1.9) (Autocrine motility factor) (AMF) (Neuroleukin) (NLK) (Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase) (PHI) Bos taurus (Bovine) gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096] GO:0004347; GO:0005125; GO:0005615; GO:0005829; GO:0006094; GO:0006096; GO:0048029; GO:0051156; GO:0097367 1386 XM_044324986.1 50 20 29 42 95 NA NA NA NA NA NA 1387 XM_044309800.1 621 396 421 404 440 B3RNE8 1.16e-59 Alpha-tubulin N-acetyltransferase (Alpha-TAT) (TAT) (EC 2.3.1.108) (Acetyltransferase mec-17 homolog) Trichoplax adhaerens (Trichoplax reptans) alpha-tubulin acetylation [GO:0071929]; regulation of microtubule cytoskeleton organization [GO:0070507] GO:0005874; GO:0019799; GO:0070507; GO:0071929 1388 XM_029344147.2 578 751 341 397 239 Q54UT2 6.83e-62 Deoxyguanosine kinase (dGK) (EC 2.7.1.113) (DddGK) Dictyostelium discoideum (Social amoeba) deoxyguanosine salvage [GO:0006180]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; phosphorylation [GO:0016310] GO:0004138; GO:0005524; GO:0005737; GO:0005747; GO:0006120; GO:0006180; GO:0016310 1389 XM_044310280.1 923 419 549 1223 953 O75096 0 Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7) Homo sapiens (Human) amyloid-beta clearance by cellular catabolic process [GO:0150094]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; proximal/distal pattern formation [GO:0009954]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0044853; GO:0048699; GO:0048813; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 1390 XM_044310280.1 923 419 549 1223 953 O75096 0 Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7) Homo sapiens (Human) amyloid-beta clearance by cellular catabolic process [GO:0150094]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; proximal/distal pattern formation [GO:0009954]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0044853; GO:0048699; GO:0048813; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 1391 XM_044310280.1 923 419 549 1223 953 O75096 0 Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7) Homo sapiens (Human) amyloid-beta clearance by cellular catabolic process [GO:0150094]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; proximal/distal pattern formation [GO:0009954]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0044853; GO:0048699; GO:0048813; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 1392 XM_044310280.1 923 419 549 1223 953 O75096 0 Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7) Homo sapiens (Human) amyloid-beta clearance by cellular catabolic process [GO:0150094]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; proximal/distal pattern formation [GO:0009954]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0044853; GO:0048699; GO:0048813; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 1393 XM_044310280.1 923 419 549 1223 953 O75096 0 Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7) Homo sapiens (Human) amyloid-beta clearance by cellular catabolic process [GO:0150094]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; proximal/distal pattern formation [GO:0009954]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0044853; GO:0048699; GO:0048813; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 1394 XM_044310280.1 923 419 549 1223 953 O75096 0 Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7) Homo sapiens (Human) amyloid-beta clearance by cellular catabolic process [GO:0150094]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; proximal/distal pattern formation [GO:0009954]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0044853; GO:0048699; GO:0048813; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 1395 XM_044310280.1 923 419 549 1223 953 O75096 0 Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7) Homo sapiens (Human) amyloid-beta clearance by cellular catabolic process [GO:0150094]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; proximal/distal pattern formation [GO:0009954]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0044853; GO:0048699; GO:0048813; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 1396 XM_044310280.1 923 419 549 1223 953 O75096 0 Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7) Homo sapiens (Human) amyloid-beta clearance by cellular catabolic process [GO:0150094]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; proximal/distal pattern formation [GO:0009954]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0044853; GO:0048699; GO:0048813; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 1397 XM_044310280.1 923 419 549 1223 953 O75096 0 Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7) Homo sapiens (Human) amyloid-beta clearance by cellular catabolic process [GO:0150094]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; proximal/distal pattern formation [GO:0009954]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0044853; GO:0048699; GO:0048813; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 1398 XM_044310280.1 923 419 549 1223 953 O75096 0 Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7) Homo sapiens (Human) amyloid-beta clearance by cellular catabolic process [GO:0150094]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; proximal/distal pattern formation [GO:0009954]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0044853; GO:0048699; GO:0048813; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 1399 XM_044318299.1 159 29 57 196 298 Q96CG8 7.42e-43 Collagen triple helix repeat-containing protein 1 Homo sapiens (Human) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005576; GO:0005581; GO:0005615; GO:0016477; GO:0016528; GO:0017147; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0062023; GO:0090090; GO:0090103; GO:0090177 1400 XM_044318299.1 159 29 57 196 298 Q96CG8 2.48e-42 Collagen triple helix repeat-containing protein 1 Homo sapiens (Human) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005576; GO:0005581; GO:0005615; GO:0016477; GO:0016528; GO:0017147; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0062023; GO:0090090; GO:0090103; GO:0090177 1401 XM_044318299.1 159 29 57 196 298 Q96CG8 6.97e-32 Collagen triple helix repeat-containing protein 1 Homo sapiens (Human) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005576; GO:0005581; GO:0005615; GO:0016477; GO:0016528; GO:0017147; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0062023; GO:0090090; GO:0090103; GO:0090177 1402 XM_044309241.1 1 0 4 24 9 NA NA NA NA NA NA 1403 XM_044309338.1 1 14 17 0 3 Q09575 1.89e-33 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 1404 XR_003828618.1 3339 2272 1303 2942 2307 NA NA NA NA NA NA 1405 XM_029356909.2 5890 3993 2748 5649 5420 O08663 0 Methionine aminopeptidase 2 (MAP 2) (MetAP 2) (EC 3.4.11.18) (Initiation factor 2-associated 67 kDa glycoprotein) (p67) (p67eIF2) (Peptidase M) Mus musculus (Mouse) N-terminal protein amino acid modification [GO:0031365]; peptidyl-methionine modification [GO:0018206]; protein initiator methionine removal involved in protein maturation [GO:0035551]; protein processing [GO:0016485] GO:0004177; GO:0005737; GO:0005829; GO:0005886; GO:0008235; GO:0016485; GO:0018206; GO:0031365; GO:0035551; GO:0046872; GO:0070006 1406 XM_044309046.1 93 63 68 154 17 P12007 3.42e-33 Isovaleryl-CoA dehydrogenase, mitochondrial (IVD) (EC 1.3.8.4) (Butyryl-CoA dehydrogenase) (EC 1.3.8.1) Rattus norvegicus (Rat) branched-chain amino acid catabolic process [GO:0009083]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; leucine catabolic process [GO:0006552]; leucine metabolic process [GO:0006551] GO:0003995; GO:0004085; GO:0005654; GO:0005739; GO:0005759; GO:0006551; GO:0006552; GO:0008470; GO:0009083; GO:0031966; GO:0033539; GO:0042802; GO:0050660 1407 XR_006396402.1 0 1 15 0 10 NA NA NA NA NA NA 1408 XM_029355855.2 1111 2297 973 913 864 Q5R8Z6 6.96e-29 Multiple coagulation factor deficiency protein 2 homolog Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] GO:0005509; GO:0005783; GO:0005793; GO:0005794; GO:0015031; GO:0016192 1409 XM_044316493.1 3 5 12 18 0 NA NA NA NA NA NA 1410 XR_006392774.1 39 15 0 15 27 NA NA NA NA NA NA 1411 XM_029351919.2 155 35 39 54 52 NA NA NA NA NA NA 1412 XR_006397073.1 339 188 307 311 552 NA NA NA NA NA NA 1413 XM_044329115.1 0 0 0 0 99 NA NA NA NA NA NA 1414 XM_029329938.2 260 29 142 264 439 Q9NSA2 1.34e-64 Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) Homo sapiens (Human) potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005250; GO:0005886; GO:0008076; GO:0014069; GO:0016020; GO:0034765; GO:0043025; GO:0043197; GO:0045211; GO:0046872; GO:0051260; GO:0071805 1415 XM_044308047.1 2235 1145 1205 1974 1842 Q8BRK8 0 5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK subunit alpha-2) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31) Mus musculus (Mouse) autophagy [GO:0006914]; cellular response to calcium ion [GO:0071277]; cellular response to glucose starvation [GO:0042149]; cellular response to glucose stimulus [GO:0071333]; cellular response to nutrient levels [GO:0031669]; cellular response to oxidative stress [GO:0034599]; cellular response to prostaglandin E stimulus [GO:0071380]; cellular response to xenobiotic stimulus [GO:0071466]; cholesterol biosynthetic process [GO:0006695]; chromatin organization [GO:0006325]; energy homeostasis [GO:0097009]; fatty acid biosynthetic process [GO:0006633]; fatty acid homeostasis [GO:0055089]; glucose homeostasis [GO:0042593]; intracellular signal transduction [GO:0035556]; lipid biosynthetic process [GO:0008610]; lipid droplet disassembly [GO:1905691]; negative regulation of apoptotic process [GO:0043066]; negative regulation of gene expression [GO:0010629]; negative regulation of TOR signaling [GO:0032007]; negative regulation of tubulin deacetylation [GO:1904428]; positive regulation of autophagy [GO:0010508]; positive regulation of glycolytic process [GO:0045821]; positive regulation of peptidyl-lysine acetylation [GO:2000758]; positive regulation of protein localization [GO:1903829]; protein localization to lipid droplet [GO:1990044]; protein phosphorylation [GO:0006468]; regulation of circadian rhythm [GO:0042752]; regulation of gene expression [GO:0010468]; regulation of lipid metabolic process [GO:0019216]; regulation of macroautophagy [GO:0016241]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of stress granule assembly [GO:0062028]; response to activity [GO:0014823]; response to caffeine [GO:0031000]; response to muscle activity [GO:0014850]; rhythmic process [GO:0048511]; Wnt signaling pathway [GO:0016055] GO:0003682; GO:0004672; GO:0004674; GO:0004679; GO:0004712; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005794; GO:0005829; GO:0006325; GO:0006468; GO:0006633; GO:0006695; GO:0006914; GO:0008610; GO:0010468; GO:0010494; GO:0010508; GO:0010629; GO:0014823; GO:0014850; GO:0016055; GO:0016241; GO:0016324; GO:0016607; GO:0019216; GO:0030424; GO:0030425; GO:0030674; GO:0031000; GO:0031588; GO:0031669; GO:0032007; GO:0032991; GO:0034599; GO:0035174; GO:0035556; GO:0042149; GO:0042593; GO:0042752; GO:0043025; GO:0043066; GO:0044877; GO:0045821; GO:0046872; GO:0047322; GO:0048511; GO:0050405; GO:0055089; GO:0062028; GO:0070507; GO:0071277; GO:0071333; GO:0071380; GO:0071466; GO:0097009; GO:0106310; GO:1903829; GO:1904428; GO:1905691; GO:1990044; GO:2000758 1416 XM_044327110.1 3 0 40 0 22 NA NA NA NA NA NA 1417 XM_029330664.2 155 96 99 77 73 Q1LU86 5.51e-50 CBY1-interacting BAR domain-containing protein 1 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; inner mitochondrial membrane organization [GO:0007007]; positive regulation of smoothened signaling pathway [GO:0045880] GO:0005634; GO:0005737; GO:0005743; GO:0005814; GO:0005929; GO:0007007; GO:0019898; GO:0035869; GO:0036064; GO:0045880; GO:0060271; GO:0097546 1418 XM_029355838.2 3568 1898 1676 2875 3136 Q99707 0 Methionine synthase (MS) (EC 2.1.1.13) (5-methyltetrahydrofolate--homocysteine methyltransferase) (Cobalamin-dependent methionine synthase) (Vitamin-B12 dependent methionine synthase) Homo sapiens (Human) axon regeneration [GO:0031103]; cellular response to nitric oxide [GO:0071732]; cobalamin metabolic process [GO:0009235]; methionine biosynthetic process [GO:0009086]; methylation [GO:0032259]; nervous system development [GO:0007399]; pteridine-containing compound metabolic process [GO:0042558]; response to axon injury [GO:0048678] GO:0005829; GO:0007399; GO:0008270; GO:0008705; GO:0009086; GO:0009235; GO:0031103; GO:0031419; GO:0032259; GO:0042558; GO:0048678; GO:0071732 1419 XM_044321730.1 25 0 0 8 0 NA NA NA NA NA NA 1420 XM_044307968.1 42 8 13 20 6 NA NA NA NA NA NA 1421 XM_044309569.1 28 31 5 17 2 NA NA NA NA NA NA 1422 XR_003823878.2 14 15 84 71 57 NA NA NA NA NA NA 1423 XR_006396345.1 7 0 12 2 20 NA NA NA NA NA NA 1424 XM_044327073.1 0 0 11 4 0 NA NA NA NA NA NA 1425 XM_044322461.1 37 12 0 1 47 Q96AY4 7.16e-82 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1426 XM_044322461.1 37 12 0 1 47 Q96AY4 7.21e-80 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1427 XM_044322461.1 37 12 0 1 47 Q96AY4 7.21e-77 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1428 XM_044322461.1 37 12 0 1 47 Q96AY4 1.22e-73 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1429 XM_044322461.1 37 12 0 1 47 Q96AY4 2.38e-62 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1430 XM_044322461.1 37 12 0 1 47 Q96AY4 1.43e-49 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1431 XM_029350590.2 456 0 0 57 0 Q6XP49 5.39e-74 Zinc finger protein GLIS3 (GLI-similar 3) Mus musculus (Mouse) negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366] GO:0000122; GO:0000977; GO:0000978; GO:0000981; GO:0001227; GO:0001228; GO:0003677; GO:0003700; GO:0005634; GO:0006357; GO:0006366; GO:0045944; GO:0046872 1432 XM_029333580.2 6 24 43 35 20 Q9R050 1.04e-56 Single-stranded DNA-binding protein 3 (Sequence-specific single-stranded-DNA-binding protein) Rattus norvegicus (Rat) DNA-templated transcription elongation [GO:0006354]; head development [GO:0060322]; head morphogenesis [GO:0060323]; hematopoietic progenitor cell differentiation [GO:0002244]; mesendoderm development [GO:0048382]; midbrain-hindbrain boundary initiation [GO:0021547]; positive regulation of anterior head development [GO:2000744]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; prechordal plate formation [GO:0021501]; protein-containing complex assembly [GO:0065003] GO:0002244; GO:0003697; GO:0003713; GO:0005634; GO:0005667; GO:0006354; GO:0008284; GO:0021501; GO:0021547; GO:0032991; GO:0045893; GO:0045944; GO:0048382; GO:0060322; GO:0060323; GO:0065003; GO:2000744 1433 XM_044323694.1 25 2 3 2 28 NA NA NA NA NA NA 1434 XM_029349640.2 232 439 432 553 1074 O57321 1.26e-131 Excitatory amino acid transporter 1 (SEAAT1) (Sodium-dependent glutamate/aspartate transporter) (GLAST) Ambystoma tigrinum (Eastern tiger salamander) chloride transmembrane transport [GO:1902476]; D-aspartate import across plasma membrane [GO:0070779]; L-aspartate import across plasma membrane [GO:0140009]; L-glutamate import across plasma membrane [GO:0098712]; potassium ion transmembrane transport [GO:0071805] GO:0005314; GO:0005886; GO:0015501; GO:0046872; GO:0070779; GO:0071805; GO:0098712; GO:0140009; GO:1902476 1435 XR_006391651.1 9 17 2 3 9 NA NA NA NA NA NA 1436 XM_044326490.1 28 0 14 4 28 A8MPY1 3.96e-24 Gamma-aminobutyric acid receptor subunit rho-3 (GABA(A) receptor subunit rho-3) (GABA(C) receptor) Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid signaling pathway [GO:0007214]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165] GO:0004890; GO:0005231; GO:0005254; GO:0005886; GO:0007165; GO:0007214; GO:0007268; GO:0030594; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:1902476; GO:1902711; GO:1904315 1437 XM_044326490.1 28 0 14 4 28 A8MPY1 3.96e-24 Gamma-aminobutyric acid receptor subunit rho-3 (GABA(A) receptor subunit rho-3) (GABA(C) receptor) Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid signaling pathway [GO:0007214]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165] GO:0004890; GO:0005231; GO:0005254; GO:0005886; GO:0007165; GO:0007214; GO:0007268; GO:0030594; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:1902476; GO:1902711; GO:1904315 1438 XM_029342569.2 82 71 75 67 101 Q25C93 3.62e-62 Fez family zinc finger protein 1 Danio rerio (Zebrafish) (Brachydanio rerio) cell differentiation [GO:0030154]; nervous system development [GO:0007399]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0003700; GO:0005634; GO:0006357; GO:0007399; GO:0030154; GO:0046872 1439 XM_029336569.2 0 0 0 0 108 P63079 2.4e-82 Gamma-aminobutyric acid receptor subunit beta-3 (GABA(A) receptor subunit beta-3) Rattus norvegicus (Rat) brain development [GO:0007420]; cellular response to histamine [GO:0071420]; cellular response to zinc ion [GO:0071294]; cerebellum development [GO:0021549]; chemical synaptic transmission [GO:0007268]; chemical synaptic transmission, postsynaptic [GO:0099565]; chloride transmembrane transport [GO:1902476]; circadian sleep/wake cycle, REM sleep [GO:0042747]; cochlea development [GO:0090102]; exploration behavior [GO:0035640]; gamma-aminobutyric acid signaling pathway [GO:0007214]; hard palate development [GO:0060022]; inhibitory postsynaptic potential [GO:0060080]; inhibitory synapse assembly [GO:1904862]; inner ear receptor cell development [GO:0060119]; innervation [GO:0060384]; ion transmembrane transport [GO:0034220]; learning [GO:0007612]; memory [GO:0007613]; motor behavior [GO:0061744]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; nervous system development [GO:0007399]; nervous system process [GO:0050877]; neuron development [GO:0048666]; regulation of membrane potential [GO:0042391]; regulation of neuron apoptotic process [GO:0043523]; regulation of postsynaptic membrane potential [GO:0060078]; reproductive behavior [GO:0019098]; response to anesthetic [GO:0072347]; response to xenobiotic stimulus [GO:0009410]; roof of mouth development [GO:0060021]; sensory perception of sound [GO:0007605]; signal transduction [GO:0007165]; social behavior [GO:0035176]; synaptic transmission, GABAergic [GO:0051932] GO:0004890; GO:0005216; GO:0005231; GO:0005254; GO:0005886; GO:0007165; GO:0007214; GO:0007268; GO:0007399; GO:0007420; GO:0007605; GO:0007612; GO:0007613; GO:0009410; GO:0009986; GO:0019098; GO:0021549; GO:0022851; GO:0030594; GO:0030659; GO:0034220; GO:0034707; GO:0035176; GO:0035612; GO:0035640; GO:0042391; GO:0042747; GO:0042802; GO:0043005; GO:0043195; GO:0043523; GO:0043524; GO:0045202; GO:0045211; GO:0048666; GO:0050877; GO:0051932; GO:0060021; GO:0060022; GO:0060077; GO:0060078; GO:0060080; GO:0060119; GO:0060384; GO:0061744; GO:0071294; GO:0071420; GO:0072347; GO:0090102; GO:0098982; GO:0099565; GO:0099634; GO:1901215; GO:1902476; GO:1902711; GO:1904315; GO:1904862 1440 XM_029345563.2 21 0 0 0 33 P26591 3.15e-94 Glutamate receptor Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004970; GO:0045211 1441 XM_044324620.1 159 92 80 67 104 Q6P606 5.15e-28 LysM and putative peptidoglycan-binding domain-containing protein 4 Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0016020 1442 XM_029358247.2 0 17 0 21 0 Q6R5J2 0 Protein dispatched homolog 1 (Protein chameleon) Danio rerio (Zebrafish) (Brachydanio rerio) adenohypophysis development [GO:0021984]; animal organ morphogenesis [GO:0009887]; anterior/posterior pattern specification [GO:0009952]; blood circulation [GO:0008015]; embryonic cranial skeleton morphogenesis [GO:0048701]; inner ear development [GO:0048839]; muscle cell fate specification [GO:0042694]; retinal ganglion cell axon guidance [GO:0031290]; skeletal muscle tissue development [GO:0007519]; smoothened signaling pathway [GO:0007224]; transmembrane transport [GO:0055085] GO:0007224; GO:0007519; GO:0008015; GO:0009887; GO:0009952; GO:0016020; GO:0021984; GO:0022857; GO:0031290; GO:0042694; GO:0048701; GO:0048839; GO:0055085; GO:1904680 1443 XM_029341633.2 1607 1071 694 992 1336 NA NA NA NA NA NA 1444 XM_029357301.2 149 82 35 101 55 Q15319 1.2e-78 POU domain, class 4, transcription factor 3 (Brain-specific homeobox/POU domain protein 3C) (Brain-3C) (Brn-3C) Homo sapiens (Human) axon extension [GO:0048675]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear morphogenesis [GO:0042472]; neuromuscular process controlling balance [GO:0050885]; neuron apoptotic process [GO:0051402]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; retinal ganglion cell axon guidance [GO:0031290]; sensory perception of sound [GO:0007605]; vestibulocochlear nerve development [GO:0021562]; visual perception [GO:0007601] GO:0000785; GO:0000978; GO:0000981; GO:0001228; GO:0003700; GO:0005634; GO:0005654; GO:0005737; GO:0006357; GO:0007601; GO:0007605; GO:0021562; GO:0031290; GO:0042472; GO:0042491; GO:0045944; GO:0048675; GO:0050885; GO:0051402; GO:1990837 1445 XM_029337679.2 646 669 371 518 419 Q5RCG9 3.52e-77 Prefoldin subunit 3 (von Hippel-Lindau-binding protein 1) (VBP-1) (VHL-binding protein 1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) negative regulation of amyloid fibril formation [GO:1905907]; protein folding [GO:0006457]; protein stabilization [GO:0050821] GO:0001540; GO:0005634; GO:0005829; GO:0006457; GO:0016272; GO:0050821; GO:0051082; GO:1905907 1446 XM_029354566.2 30 9 5 6 52 NA NA NA NA NA NA 1447 XR_006395559.1 120 68 117 48 9 Q9UBN7 2.06e-66 Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-) Homo sapiens (Human) aggresome assembly [GO:0070842]; autophagy [GO:0006914]; axonal transport of mitochondrion [GO:0019896]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to misfolded protein [GO:0071218]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to topologically incorrect protein [GO:0035967]; cilium assembly [GO:0060271]; cilium disassembly [GO:0061523]; collateral sprouting [GO:0048668]; dendritic spine morphogenesis [GO:0060997]; epigenetic regulation of gene expression [GO:0040029]; histone deacetylation [GO:0016575]; Hsp90 deacetylation [GO:0070846]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of protein-containing complex disassembly [GO:0043242]; negative regulation of proteolysis [GO:0045861]; negative regulation of transcription by RNA polymerase II [GO:0000122]; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:0061734]; peptidyl-lysine deacetylation [GO:0034983]; polyubiquitinated misfolded protein transport [GO:0070845]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of hydrogen peroxide-mediated programmed cell death [GO:1901300]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of tubulin deacetylation [GO:0090044]; protein deacetylation [GO:0006476]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; protein-containing complex disassembly [GO:0032984]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of autophagy [GO:0010506]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of establishment of protein localization [GO:0070201]; regulation of fat cell differentiation [GO:0045598]; regulation of macroautophagy [GO:0016241]; regulation of microtubule-based movement [GO:0060632]; regulation of protein stability [GO:0031647]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]; response to dexamethasone [GO:0071548]; response to growth factor [GO:0070848]; response to immobilization stress [GO:0035902]; response to misfolded protein [GO:0051788]; tubulin deacetylation [GO:0090042]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] GO:0000118; GO:0000122; GO:0000209; GO:0000978; GO:0001222; GO:0001975; GO:0003779; GO:0004407; GO:0005634; GO:0005654; GO:0005737; GO:0005771; GO:0005813; GO:0005829; GO:0005874; GO:0005875; GO:0005901; GO:0006476; GO:0006515; GO:0006886; GO:0006914; GO:0007026; GO:0008013; GO:0008017; GO:0008270; GO:0010506; GO:0010634; GO:0010727; GO:0016234; GO:0016235; GO:0016241; GO:0016575; GO:0019896; GO:0019899; GO:0030424; GO:0030425; GO:0031252; GO:0031333; GO:0031593; GO:0031625; GO:0031647; GO:0031648; GO:0032418; GO:0032984; GO:0033138; GO:0033558; GO:0034983; GO:0035902; GO:0035967; GO:0036064; GO:0040029; GO:0042826; GO:0042903; GO:0043014; GO:0043130; GO:0043162; GO:0043204; GO:0043242; GO:0045598; GO:0045861; GO:0045892; GO:0048156; GO:0048471; GO:0048487; GO:0048668; GO:0048843; GO:0050775; GO:0051354; GO:0051412; GO:0051787; GO:0051788; GO:0051879; GO:0051968; GO:0060271; GO:0060632; GO:0060765; GO:0060997; GO:0061523; GO:0061734; GO:0070201; GO:0070301; GO:0070840; GO:0070842; GO:0070845; GO:0070846; GO:0070848; GO:0071218; GO:0071374; GO:0071548; GO:0090042; GO:0090044; GO:1901300; GO:1901984; GO:1903146; GO:1903223; GO:1904056; GO:1904115; GO:2000273 1448 XR_006395559.1 120 68 117 48 9 Q9UBN7 2.06e-66 Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-) Homo sapiens (Human) aggresome assembly [GO:0070842]; autophagy [GO:0006914]; axonal transport of mitochondrion [GO:0019896]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to misfolded protein [GO:0071218]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to topologically incorrect protein [GO:0035967]; cilium assembly [GO:0060271]; cilium disassembly [GO:0061523]; collateral sprouting [GO:0048668]; dendritic spine morphogenesis [GO:0060997]; epigenetic regulation of gene expression [GO:0040029]; histone deacetylation [GO:0016575]; Hsp90 deacetylation [GO:0070846]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of protein-containing complex disassembly [GO:0043242]; negative regulation of proteolysis [GO:0045861]; negative regulation of transcription by RNA polymerase II [GO:0000122]; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:0061734]; peptidyl-lysine deacetylation [GO:0034983]; polyubiquitinated misfolded protein transport [GO:0070845]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of hydrogen peroxide-mediated programmed cell death [GO:1901300]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of tubulin deacetylation [GO:0090044]; protein deacetylation [GO:0006476]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; protein-containing complex disassembly [GO:0032984]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of autophagy [GO:0010506]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of establishment of protein localization [GO:0070201]; regulation of fat cell differentiation [GO:0045598]; regulation of macroautophagy [GO:0016241]; regulation of microtubule-based movement [GO:0060632]; regulation of protein stability [GO:0031647]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]; response to dexamethasone [GO:0071548]; response to growth factor [GO:0070848]; response to immobilization stress [GO:0035902]; response to misfolded protein [GO:0051788]; tubulin deacetylation [GO:0090042]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] GO:0000118; GO:0000122; GO:0000209; GO:0000978; GO:0001222; GO:0001975; GO:0003779; GO:0004407; GO:0005634; GO:0005654; GO:0005737; GO:0005771; GO:0005813; GO:0005829; GO:0005874; GO:0005875; GO:0005901; GO:0006476; GO:0006515; GO:0006886; GO:0006914; GO:0007026; GO:0008013; GO:0008017; GO:0008270; GO:0010506; GO:0010634; GO:0010727; GO:0016234; GO:0016235; GO:0016241; GO:0016575; GO:0019896; GO:0019899; GO:0030424; GO:0030425; GO:0031252; GO:0031333; GO:0031593; GO:0031625; GO:0031647; GO:0031648; GO:0032418; GO:0032984; GO:0033138; GO:0033558; GO:0034983; GO:0035902; GO:0035967; GO:0036064; GO:0040029; GO:0042826; GO:0042903; GO:0043014; GO:0043130; GO:0043162; GO:0043204; GO:0043242; GO:0045598; GO:0045861; GO:0045892; GO:0048156; GO:0048471; GO:0048487; GO:0048668; GO:0048843; GO:0050775; GO:0051354; GO:0051412; GO:0051787; GO:0051788; GO:0051879; GO:0051968; GO:0060271; GO:0060632; GO:0060765; GO:0060997; GO:0061523; GO:0061734; GO:0070201; GO:0070301; GO:0070840; GO:0070842; GO:0070845; GO:0070846; GO:0070848; GO:0071218; GO:0071374; GO:0071548; GO:0090042; GO:0090044; GO:1901300; GO:1901984; GO:1903146; GO:1903223; GO:1904056; GO:1904115; GO:2000273 1449 XR_006395559.1 120 68 117 48 9 Q9UBN7 1.17e-61 Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-) Homo sapiens (Human) aggresome assembly [GO:0070842]; autophagy [GO:0006914]; axonal transport of mitochondrion [GO:0019896]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to misfolded protein [GO:0071218]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to topologically incorrect protein [GO:0035967]; cilium assembly [GO:0060271]; cilium disassembly [GO:0061523]; collateral sprouting [GO:0048668]; dendritic spine morphogenesis [GO:0060997]; epigenetic regulation of gene expression [GO:0040029]; histone deacetylation [GO:0016575]; Hsp90 deacetylation [GO:0070846]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of protein-containing complex disassembly [GO:0043242]; negative regulation of proteolysis [GO:0045861]; negative regulation of transcription by RNA polymerase II [GO:0000122]; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:0061734]; peptidyl-lysine deacetylation [GO:0034983]; polyubiquitinated misfolded protein transport [GO:0070845]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of hydrogen peroxide-mediated programmed cell death [GO:1901300]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of tubulin deacetylation [GO:0090044]; protein deacetylation [GO:0006476]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; protein-containing complex disassembly [GO:0032984]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of autophagy [GO:0010506]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of establishment of protein localization [GO:0070201]; regulation of fat cell differentiation [GO:0045598]; regulation of macroautophagy [GO:0016241]; regulation of microtubule-based movement [GO:0060632]; regulation of protein stability [GO:0031647]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]; response to dexamethasone [GO:0071548]; response to growth factor [GO:0070848]; response to immobilization stress [GO:0035902]; response to misfolded protein [GO:0051788]; tubulin deacetylation [GO:0090042]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] GO:0000118; GO:0000122; GO:0000209; GO:0000978; GO:0001222; GO:0001975; GO:0003779; GO:0004407; GO:0005634; GO:0005654; GO:0005737; GO:0005771; GO:0005813; GO:0005829; GO:0005874; GO:0005875; GO:0005901; GO:0006476; GO:0006515; GO:0006886; GO:0006914; GO:0007026; GO:0008013; GO:0008017; GO:0008270; GO:0010506; GO:0010634; GO:0010727; GO:0016234; GO:0016235; GO:0016241; GO:0016575; GO:0019896; GO:0019899; GO:0030424; GO:0030425; GO:0031252; GO:0031333; GO:0031593; GO:0031625; GO:0031647; GO:0031648; GO:0032418; GO:0032984; GO:0033138; GO:0033558; GO:0034983; GO:0035902; GO:0035967; GO:0036064; GO:0040029; GO:0042826; GO:0042903; GO:0043014; GO:0043130; GO:0043162; GO:0043204; GO:0043242; GO:0045598; GO:0045861; GO:0045892; GO:0048156; GO:0048471; GO:0048487; GO:0048668; GO:0048843; GO:0050775; GO:0051354; GO:0051412; GO:0051787; GO:0051788; GO:0051879; GO:0051968; GO:0060271; GO:0060632; GO:0060765; GO:0060997; GO:0061523; GO:0061734; GO:0070201; GO:0070301; GO:0070840; GO:0070842; GO:0070845; GO:0070846; GO:0070848; GO:0071218; GO:0071374; GO:0071548; GO:0090042; GO:0090044; GO:1901300; GO:1901984; GO:1903146; GO:1903223; GO:1904056; GO:1904115; GO:2000273 1450 XR_006395559.1 120 68 117 48 9 Q9UBN7 8.33e-23 Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-) Homo sapiens (Human) aggresome assembly [GO:0070842]; autophagy [GO:0006914]; axonal transport of mitochondrion [GO:0019896]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to misfolded protein [GO:0071218]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to topologically incorrect protein [GO:0035967]; cilium assembly [GO:0060271]; cilium disassembly [GO:0061523]; collateral sprouting [GO:0048668]; dendritic spine morphogenesis [GO:0060997]; epigenetic regulation of gene expression [GO:0040029]; histone deacetylation [GO:0016575]; Hsp90 deacetylation [GO:0070846]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of protein-containing complex disassembly [GO:0043242]; negative regulation of proteolysis [GO:0045861]; negative regulation of transcription by RNA polymerase II [GO:0000122]; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:0061734]; peptidyl-lysine deacetylation [GO:0034983]; polyubiquitinated misfolded protein transport [GO:0070845]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of hydrogen peroxide-mediated programmed cell death [GO:1901300]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of tubulin deacetylation [GO:0090044]; protein deacetylation [GO:0006476]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; protein-containing complex disassembly [GO:0032984]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of autophagy [GO:0010506]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of establishment of protein localization [GO:0070201]; regulation of fat cell differentiation [GO:0045598]; regulation of macroautophagy [GO:0016241]; regulation of microtubule-based movement [GO:0060632]; regulation of protein stability [GO:0031647]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]; response to dexamethasone [GO:0071548]; response to growth factor [GO:0070848]; response to immobilization stress [GO:0035902]; response to misfolded protein [GO:0051788]; tubulin deacetylation [GO:0090042]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] GO:0000118; GO:0000122; GO:0000209; GO:0000978; GO:0001222; GO:0001975; GO:0003779; GO:0004407; GO:0005634; GO:0005654; GO:0005737; GO:0005771; GO:0005813; GO:0005829; GO:0005874; GO:0005875; GO:0005901; GO:0006476; GO:0006515; GO:0006886; GO:0006914; GO:0007026; GO:0008013; GO:0008017; GO:0008270; GO:0010506; GO:0010634; GO:0010727; GO:0016234; GO:0016235; GO:0016241; GO:0016575; GO:0019896; GO:0019899; GO:0030424; GO:0030425; GO:0031252; GO:0031333; GO:0031593; GO:0031625; GO:0031647; GO:0031648; GO:0032418; GO:0032984; GO:0033138; GO:0033558; GO:0034983; GO:0035902; GO:0035967; GO:0036064; GO:0040029; GO:0042826; GO:0042903; GO:0043014; GO:0043130; GO:0043162; GO:0043204; GO:0043242; GO:0045598; GO:0045861; GO:0045892; GO:0048156; GO:0048471; GO:0048487; GO:0048668; GO:0048843; GO:0050775; GO:0051354; GO:0051412; GO:0051787; GO:0051788; GO:0051879; GO:0051968; GO:0060271; GO:0060632; GO:0060765; GO:0060997; GO:0061523; GO:0061734; GO:0070201; GO:0070301; GO:0070840; GO:0070842; GO:0070845; GO:0070846; GO:0070848; GO:0071218; GO:0071374; GO:0071548; GO:0090042; GO:0090044; GO:1901300; GO:1901984; GO:1903146; GO:1903223; GO:1904056; GO:1904115; GO:2000273 1451 XR_006395559.1 120 68 117 48 9 Q9UBN7 3.98e-22 Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-) Homo sapiens (Human) aggresome assembly [GO:0070842]; autophagy [GO:0006914]; axonal transport of mitochondrion [GO:0019896]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to misfolded protein [GO:0071218]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to topologically incorrect protein [GO:0035967]; cilium assembly [GO:0060271]; cilium disassembly [GO:0061523]; collateral sprouting [GO:0048668]; dendritic spine morphogenesis [GO:0060997]; epigenetic regulation of gene expression [GO:0040029]; histone deacetylation [GO:0016575]; Hsp90 deacetylation [GO:0070846]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of protein-containing complex disassembly [GO:0043242]; negative regulation of proteolysis [GO:0045861]; negative regulation of transcription by RNA polymerase II [GO:0000122]; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:0061734]; peptidyl-lysine deacetylation [GO:0034983]; polyubiquitinated misfolded protein transport [GO:0070845]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of hydrogen peroxide-mediated programmed cell death [GO:1901300]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of tubulin deacetylation [GO:0090044]; protein deacetylation [GO:0006476]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; protein-containing complex disassembly [GO:0032984]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of autophagy [GO:0010506]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of establishment of protein localization [GO:0070201]; regulation of fat cell differentiation [GO:0045598]; regulation of macroautophagy [GO:0016241]; regulation of microtubule-based movement [GO:0060632]; regulation of protein stability [GO:0031647]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]; response to dexamethasone [GO:0071548]; response to growth factor [GO:0070848]; response to immobilization stress [GO:0035902]; response to misfolded protein [GO:0051788]; tubulin deacetylation [GO:0090042]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] GO:0000118; GO:0000122; GO:0000209; GO:0000978; GO:0001222; GO:0001975; GO:0003779; GO:0004407; GO:0005634; GO:0005654; GO:0005737; GO:0005771; GO:0005813; GO:0005829; GO:0005874; GO:0005875; GO:0005901; GO:0006476; GO:0006515; GO:0006886; GO:0006914; GO:0007026; GO:0008013; GO:0008017; GO:0008270; GO:0010506; GO:0010634; GO:0010727; GO:0016234; GO:0016235; GO:0016241; GO:0016575; GO:0019896; GO:0019899; GO:0030424; GO:0030425; GO:0031252; GO:0031333; GO:0031593; GO:0031625; GO:0031647; GO:0031648; GO:0032418; GO:0032984; GO:0033138; GO:0033558; GO:0034983; GO:0035902; GO:0035967; GO:0036064; GO:0040029; GO:0042826; GO:0042903; GO:0043014; GO:0043130; GO:0043162; GO:0043204; GO:0043242; GO:0045598; GO:0045861; GO:0045892; GO:0048156; GO:0048471; GO:0048487; GO:0048668; GO:0048843; GO:0050775; GO:0051354; GO:0051412; GO:0051787; GO:0051788; GO:0051879; GO:0051968; GO:0060271; GO:0060632; GO:0060765; GO:0060997; GO:0061523; GO:0061734; GO:0070201; GO:0070301; GO:0070840; GO:0070842; GO:0070845; GO:0070846; GO:0070848; GO:0071218; GO:0071374; GO:0071548; GO:0090042; GO:0090044; GO:1901300; GO:1901984; GO:1903146; GO:1903223; GO:1904056; GO:1904115; GO:2000273 1452 XM_029357994.2 119 64 59 130 352 P35445 3.63e-129 Cartilage oligomeric matrix protein (COMP) Bos taurus (Bovine) apoptotic process [GO:0006915]; artery morphogenesis [GO:0048844]; BMP signaling pathway [GO:0030509]; bone mineralization [GO:0030282]; cartilage homeostasis [GO:1990079]; chondrocyte development [GO:0002063]; chondrocyte proliferation [GO:0035988]; collagen fibril organization [GO:0030199]; growth plate cartilage development [GO:0003417]; limb development [GO:0060173]; multicellular organism aging [GO:0010259]; multicellular organism growth [GO:0035264]; musculoskeletal movement [GO:0050881]; negative regulation of apoptotic process [GO:0043066]; negative regulation of hemostasis [GO:1900047]; platelet aggregation [GO:0070527]; positive regulation of chondrocyte proliferation [GO:1902732]; protein homooligomerization [GO:0051260]; protein processing [GO:0016485]; protein secretion [GO:0009306]; regulation of bone mineralization [GO:0030500]; regulation of gene expression [GO:0010468]; response to unfolded protein [GO:0006986]; skin development [GO:0043588]; tendon development [GO:0035989]; vascular associated smooth muscle cell development [GO:0097084]; vascular associated smooth muscle contraction [GO:0014829] GO:0002020; GO:0002063; GO:0003417; GO:0005178; GO:0005509; GO:0005518; GO:0005576; GO:0005615; GO:0006915; GO:0006986; GO:0008201; GO:0009306; GO:0010259; GO:0010468; GO:0014829; GO:0016485; GO:0030199; GO:0030282; GO:0030500; GO:0030509; GO:0032991; GO:0035264; GO:0035988; GO:0035989; GO:0036122; GO:0043066; GO:0043395; GO:0043588; GO:0048844; GO:0050881; GO:0051260; GO:0060173; GO:0062023; GO:0070527; GO:0097084; GO:1900047; GO:1902732; GO:1990079 1453 XM_029355700.2 6358 5145 2784 4382 3183 NA NA NA NA NA NA 1454 XR_006396209.1 92 61 52 36 79 Q5R9I3 2.03e-21 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cellular response to glucose starvation [GO:0042149]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; protein phosphorylation [GO:0006468] GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005930; GO:0006468; GO:0016236; GO:0035032; GO:0042149; GO:0045324; GO:0106310 1455 XM_044317397.1 36 25 2 45 39 Q8LHH9 1.27e-147 Probable RNA-dependent RNA polymerase SHL2 (EC 2.7.7.48) (Protein SHOOTLESS 2) Oryza sativa subsp. japonica (Rice) maintenance of shoot apical meristem identity [GO:0010492]; RNA-mediated post-transcriptional gene silencing [GO:0035194]; siRNA processing [GO:0030422] GO:0003723; GO:0003968; GO:0010492; GO:0030422; GO:0031380; GO:0035194 1456 XM_029338691.2 56 46 42 167 122 NA NA NA NA NA NA 1457 XM_044311452.1 105 29 65 71 39 Q95SX7 2.6e-30 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 1458 XM_029330768.2 0 0 75 0 0 D3ZR10 1.7e-26 Doublecortin domain-containing protein 2 Rattus norvegicus (Rat) cilium assembly [GO:0060271]; dendrite morphogenesis [GO:0048813]; intracellular signal transduction [GO:0035556]; neuron migration [GO:0001764]; neuronal action potential [GO:0019228]; positive regulation of smoothened signaling pathway [GO:0045880]; regulation of cilium assembly [GO:1902017]; regulation of Wnt signaling pathway [GO:0030111]; sensory perception of sound [GO:0007605]; synaptic transmission, glutamatergic [GO:0035249]; visual learning [GO:0008542] GO:0001764; GO:0005737; GO:0005815; GO:0005829; GO:0005856; GO:0005874; GO:0005929; GO:0005930; GO:0007605; GO:0008542; GO:0019228; GO:0019894; GO:0030111; GO:0034451; GO:0035249; GO:0035556; GO:0045202; GO:0045880; GO:0048813; GO:0060091; GO:0060271; GO:0072686; GO:1902017 1459 XM_044326666.1 460 198 76 496 411 NA NA NA NA NA NA 1460 XM_029338337.2 529 382 334 519 378 NA NA NA NA NA NA 1461 XM_029344502.2 7 0 1 0 21 Q4R856 2.63e-23 RAD52 motif-containing protein 1 Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) DNA metabolic process [GO:0006259] GO:0003677; GO:0003723; GO:0005730; GO:0005829; GO:0006259; GO:0015030; GO:0016605 1462 XM_044325338.1 0 0 0 0 240 Q8JGM4 3.49e-95 Sulfhydryl oxidase 1 (EC 1.8.3.2) (Quiescin Q6) Gallus gallus (Chicken) protein folding [GO:0006457] GO:0000139; GO:0003756; GO:0005615; GO:0006457; GO:0016971 1463 XM_044312367.1 0 0 6 0 13 Q3KQG9 1.14e-56 Testicular acid phosphatase homolog (EC 3.1.3.2) (Acid phosphatase 4) Xenopus laevis (African clawed frog) NA GO:0003993; GO:0016020 1464 XR_006396386.1 45 0 146 110 89 NA NA NA NA NA NA 1465 XR_003824689.2 170 172 155 94 171 NA NA NA NA NA NA 1466 XM_029328631.2 27 44 54 54 138 Q9GLP1 3.51e-25 Coagulation factor V (Activated protein C cofactor) [Cleaved into: Coagulation factor V heavy chain; Coagulation factor V light chain] Sus scrofa (Pig) blood circulation [GO:0008015]; blood coagulation [GO:0007596] GO:0005507; GO:0005576; GO:0007596; GO:0008015; GO:0031091 1467 XM_044313543.1 0 24 0 0 1 NA NA NA NA NA NA 1468 XM_029335770.2 134 0 122 0 152 P69478 5.51e-50 Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4S-1) (C4ST-1) (C4ST1) Rattus norvegicus (Rat) apoptotic process [GO:0006915]; carbohydrate biosynthetic process [GO:0016051]; cartilage development [GO:0051216]; chondrocyte development [GO:0002063]; chondroitin sulfate biosynthetic process [GO:0030206]; chondroitin sulfate metabolic process [GO:0030204]; developmental growth [GO:0048589]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; embryonic viscerocranium morphogenesis [GO:0048703]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; polysaccharide localization [GO:0033037]; post-anal tail morphogenesis [GO:0036342]; post-embryonic development [GO:0009791]; proteoglycan biosynthetic process [GO:0030166]; regulation of cell population proliferation [GO:0042127]; respiratory gaseous exchange by respiratory system [GO:0007585]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0000139; GO:0001537; GO:0001701; GO:0002063; GO:0006915; GO:0007179; GO:0007585; GO:0008146; GO:0009791; GO:0016051; GO:0030166; GO:0030204; GO:0030206; GO:0030326; GO:0030512; GO:0033037; GO:0036342; GO:0042127; GO:0042733; GO:0043066; GO:0047756; GO:0048589; GO:0048703; GO:0048704; GO:0050659; GO:0051216 1469 XM_029351654.2 90 199 109 282 108 P12256 4.34e-37 Penicillin acylase (EC 3.5.1.11) (Penicillin V amidase) (PVA) Lysinibacillus sphaericus (Bacillus sphaericus) response to antibiotic [GO:0046677] GO:0008953; GO:0046677 1470 XM_029345920.2 314 233 173 277 247 NA NA NA NA NA NA 1471 XM_029330978.2 2094 1965 1066 1686 2249 Q9Y2L9 1.02e-55 Leucine-rich repeat and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1) (Neuronal protein 81) (NP81) Homo sapiens (Human) cellular response to chemokine [GO:1990869]; negative regulation of GTPase activity [GO:0034260]; negative regulation of T cell migration [GO:2000405] GO:0005737; GO:0034260; GO:1990869; GO:2000405 1472 XM_029330978.2 2094 1965 1066 1686 2249 Q9Y2L9 3.78e-32 Leucine-rich repeat and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1) (Neuronal protein 81) (NP81) Homo sapiens (Human) cellular response to chemokine [GO:1990869]; negative regulation of GTPase activity [GO:0034260]; negative regulation of T cell migration [GO:2000405] GO:0005737; GO:0034260; GO:1990869; GO:2000405 1473 XM_044320107.1 5 0 13 8 7 NA NA NA NA NA NA 1474 XR_006396805.1 598 255 263 290 322 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 1475 XR_006396805.1 598 255 263 290 322 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 1476 XR_006396805.1 598 255 263 290 322 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 1477 XR_006396805.1 598 255 263 290 322 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 1478 XR_006396805.1 598 255 263 290 322 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 1479 XR_006396805.1 598 255 263 290 322 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 1480 XR_006396805.1 598 255 263 290 322 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 1481 XR_006396805.1 598 255 263 290 322 P07207 1.89e-97 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 1482 XR_006396805.1 598 255 263 290 322 P07207 3.99e-96 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 1483 XR_006396805.1 598 255 263 290 322 P07207 5.05e-91 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 1484 XR_006396805.1 598 255 263 290 322 P07207 2.33e-87 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 1485 XR_006396805.1 598 255 263 290 322 P07207 1.78e-86 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 1486 XR_006396805.1 598 255 263 290 322 P07207 1.53e-84 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 1487 XR_006396805.1 598 255 263 290 322 P07207 4.79e-84 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 1488 XR_006396805.1 598 255 263 290 322 P07207 1.09e-79 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 1489 XR_006396805.1 598 255 263 290 322 P07207 8.41e-52 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 1490 XR_006396805.1 598 255 263 290 322 P07207 4.94e-45 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 1491 XR_006396805.1 598 255 263 290 322 P07207 3.81e-43 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 1492 XR_006396805.1 598 255 263 290 322 P07207 4.08e-43 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 1493 XR_006396805.1 598 255 263 290 322 P07207 9.69e-42 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 1494 XR_006396805.1 598 255 263 290 322 P07207 7.59e-40 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 1495 XR_006396805.1 598 255 263 290 322 P07207 1.54e-39 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 1496 XR_006396805.1 598 255 263 290 322 P07207 1.82e-39 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 1497 XR_006396805.1 598 255 263 290 322 P07207 6.46e-37 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 1498 XR_006396805.1 598 255 263 290 322 P07207 1.64e-35 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 1499 XR_006396805.1 598 255 263 290 322 P07207 1.96e-34 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 1500 XR_006396805.1 598 255 263 290 322 P07207 4.76e-34 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 1501 XR_006396805.1 598 255 263 290 322 P07207 7.07e-34 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 1502 XR_006396805.1 598 255 263 290 322 P07207 1.24e-31 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 1503 XR_006396805.1 598 255 263 290 322 P07207 3.15e-31 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 1504 XR_006396805.1 598 255 263 290 322 P07207 4.63e-31 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 1505 XR_006396805.1 598 255 263 290 322 P07207 3.22e-30 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 1506 XR_006396805.1 598 255 263 290 322 P07207 3.78e-30 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 1507 XR_006396805.1 598 255 263 290 322 P07207 1.29e-29 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 1508 XR_006396805.1 598 255 263 290 322 P07207 3.5e-29 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 1509 XR_006396805.1 598 255 263 290 322 P07207 1.07e-21 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 1510 XR_006396805.1 598 255 263 290 322 P07207 2.86e-21 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 1511 XM_044328355.1 153 144 9 95 39 Q96AY4 8.49e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1512 XM_029337602.2 0 423 2 57 35 NA NA NA NA NA NA 1513 XM_029356887.2 3 6 2 11 18 NA NA NA NA NA NA 1514 XM_044321359.1 347 37 296 5 221 NA NA NA NA NA NA 1515 XM_044321568.1 33 59 30 36 62 NA NA NA NA NA NA 1516 XR_006395656.1 83 273 132 101 113 NA NA NA NA NA NA 1517 XM_029356436.2 84 257 8 281 200 NA NA NA NA NA NA 1518 XM_029333316.2 127 17 0 17 0 Q12923 2.53e-57 Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1) (PTP-BAS) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (Protein-tyrosine phosphatase PTPL1) Homo sapiens (Human) cellular response to toxic substance [GO:0097237]; negative regulation of excitatory synapse assembly [GO:1904890]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066] GO:0001650; GO:0001933; GO:0004725; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0006470; GO:0014066; GO:0030027; GO:0035335; GO:0036312; GO:0043005; GO:0044297; GO:0070062; GO:0097237; GO:1904890 1519 XM_029333316.2 127 17 0 17 0 Q12923 1.88e-28 Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1) (PTP-BAS) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (Protein-tyrosine phosphatase PTPL1) Homo sapiens (Human) cellular response to toxic substance [GO:0097237]; negative regulation of excitatory synapse assembly [GO:1904890]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066] GO:0001650; GO:0001933; GO:0004725; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0006470; GO:0014066; GO:0030027; GO:0035335; GO:0036312; GO:0043005; GO:0044297; GO:0070062; GO:0097237; GO:1904890 1520 XM_029331887.2 0 84 47 185 503 O57460 1.5e-35 Dorsal-ventral patterning tolloid-like protein 1 (EC 3.4.24.-) (Mini fin protein) Danio rerio (Zebrafish) (Brachydanio rerio) blood vessel development [GO:0001568]; determination of ventral identity [GO:0048264]; dorsal/ventral pattern formation [GO:0009953]; embryonic caudal fin morphogenesis [GO:0035124]; embryonic hemopoiesis [GO:0035162]; endothelial cell development [GO:0001885]; mesoderm formation [GO:0001707]; positive regulation of BMP signaling pathway [GO:0030513]; post-anal tail morphogenesis [GO:0036342]; protein processing [GO:0016485]; proteolysis [GO:0006508] GO:0001568; GO:0001707; GO:0001885; GO:0004222; GO:0005509; GO:0005576; GO:0005615; GO:0006508; GO:0008233; GO:0008237; GO:0008270; GO:0009953; GO:0016485; GO:0030513; GO:0035124; GO:0035162; GO:0036342; GO:0048264 1521 XR_006396015.1 97 99 50 53 89 NA NA NA NA NA NA 1522 XM_044322213.1 178 90 57 267 168 NA NA NA NA NA NA 1523 XR_003825973.2 14 11 0 0 0 NA NA NA NA NA NA 1524 XR_006397776.1 0 0 2 21 13 NA NA NA NA NA NA 1525 XR_006394818.1 239 39 0 16 0 NA NA NA NA NA NA 1526 XM_044320472.1 348 188 248 439 1265 NA NA NA NA NA NA 1527 XM_029351567.2 363 247 172 267 149 Q5EAR5 1.68e-70 tRNA 2'-phosphotransferase 1 (EC 2.7.1.160) Danio rerio (Zebrafish) (Brachydanio rerio) tRNA processing [GO:0008033]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388] GO:0000215; GO:0006388; GO:0008033 1528 XM_044318412.1 46 2 45 107 245 P14381 1.9e-31 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 1529 XM_029345816.2 13 19 65 90 72 Q08D69 1.42e-117 Mediator of RNA polymerase II transcription subunit 16 (Mediator complex subunit 16) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0016592 1530 XM_029324582.2 576 277 121 452 66 F1Q7H8 7.88e-102 Palmitoyltransferase ZDHHC20-A (EC 2.3.1.225) (Acyltransferase ZDHHC20-A) (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 20-A) Danio rerio (Zebrafish) (Brachydanio rerio) peptidyl-L-cysteine S-palmitoylation [GO:0018230]; protein palmitoylation [GO:0018345]; protein targeting to membrane [GO:0006612] GO:0000139; GO:0005783; GO:0005789; GO:0005794; GO:0005886; GO:0006612; GO:0018230; GO:0018345; GO:0019705; GO:0019706; GO:0033116; GO:0046872; GO:0048471; GO:0140439 1531 XM_029323536.2 124 115 132 91 177 O70579 1.47e-94 Peroxisomal membrane protein PMP34 (34 kDa peroxisomal membrane protein) (Solute carrier family 25 member 17) Mus musculus (Mouse) ADP transport [GO:0015866]; AMP transport [GO:0080121]; ATP transport [GO:0015867]; coenzyme A transmembrane transport [GO:0035349]; FAD transmembrane transport [GO:0035350]; fatty acid beta-oxidation [GO:0006635]; fatty acid transport [GO:0015908]; NAD transport [GO:0043132] GO:0005347; GO:0005739; GO:0005777; GO:0005778; GO:0006635; GO:0015217; GO:0015228; GO:0015230; GO:0015866; GO:0015867; GO:0015908; GO:0016020; GO:0035349; GO:0035350; GO:0043132; GO:0044610; GO:0051087; GO:0051724; GO:0080121; GO:0080122 1532 XM_044307009.1 94 89 244 69 81 NA NA NA NA NA NA 1533 XM_029328985.2 16 0 9 17 18 NA NA NA NA NA NA 1534 XM_029355879.2 693 754 762 906 1069 Q6GN70 4.85e-79 B9 domain-containing protein 2 Xenopus laevis (African clawed frog) cilium assembly [GO:0060271] GO:0005737; GO:0005813; GO:0036038; GO:0036064; GO:0043015; GO:0060271 1535 XM_029339414.2 761 900 441 683 591 O18883 2.42e-78 Thioredoxin domain-containing protein 9 (Protein 1-4) Bos taurus (Bovine) NA GO:0005634; GO:0005737; GO:0005815; GO:0030496 1536 XM_044319442.1 65 7 150 5 106 NA NA NA NA NA NA 1537 XR_006395790.1 56 86 136 55 157 NA NA NA NA NA NA 1538 XM_044314916.1 115 0 33 1 57 NA NA NA NA NA NA 1539 XM_029350635.2 81 85 80 155 152 NA NA NA NA NA NA 1540 XM_044319561.1 11 2 2 2 10 NA NA NA NA NA NA 1541 XM_044309402.1 6 2 0 2 10 NA NA NA NA NA NA 1542 XM_044312399.1 0 1 0 8 0 NA NA NA NA NA NA 1543 XR_006393780.1 2 1 12 2 23 NA NA NA NA NA NA 1544 XM_029329819.2 184 250 254 180 325 Q8NG68 2.87e-103 Tubulin--tyrosine ligase (TTL) (EC 6.3.2.25) Homo sapiens (Human) microtubule cytoskeleton organization [GO:0000226]; positive regulation of mitotic cell cycle [GO:0045931]; post-translational protein modification [GO:0043687]; regulation of axon extension [GO:0030516]; regulation of metaphase plate congression [GO:0090235] GO:0000226; GO:0004835; GO:0005524; GO:0005876; GO:0030516; GO:0043687; GO:0045931; GO:0090235 1545 XM_029325840.2 67 169 0 69 90 NA NA NA NA NA NA 1546 XM_029337538.2 0 97 65 0 0 Q9YHV3 1.75e-33 Noggin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cartilage development [GO:0051216]; cloaca development [GO:0035844]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic viscerocranium morphogenesis [GO:0048703]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell differentiation [GO:0045596]; osteoblast differentiation [GO:0001649]; pronephros development [GO:0048793] GO:0001649; GO:0005615; GO:0007368; GO:0009953; GO:0030514; GO:0035844; GO:0045596; GO:0048703; GO:0048793; GO:0051216 1547 XM_044310642.1 0 0 11 0 0 NA NA NA NA NA NA 1548 XM_029358123.2 11008 12455 4867 8839 8476 Q642H9 1.11e-139 40S ribosomal protein S4, X isoform Danio rerio (Zebrafish) (Brachydanio rerio) brain development [GO:0007420]; chordate embryonic development [GO:0043009]; translation [GO:0006412] GO:0003723; GO:0003735; GO:0006412; GO:0007420; GO:0019843; GO:0022627; GO:0043009 1549 XM_029349994.2 1 3 6 8 12 NA NA NA NA NA NA 1550 XM_044318189.1 0 10 0 0 115 NA NA NA NA NA NA 1551 XM_044324561.1 8 3 0 3 16 NA NA NA NA NA NA 1552 XM_044309160.1 16 5 0 0 0 NA NA NA NA NA NA 1553 XM_029347078.2 263 209 167 220 308 Q8BH60 2.24e-131 Golgi-associated PDZ and coiled-coil motif-containing protein (CFTR-associated ligand) (PDZ protein interacting specifically with TC10) (PIST) Mus musculus (Mouse) autophagy [GO:0006914]; negative regulation of anion channel activity [GO:0010360]; negative regulation of protein localization to cell surface [GO:2000009]; protein transport [GO:0015031]; spermatid nucleus differentiation [GO:0007289] GO:0000139; GO:0005109; GO:0005737; GO:0005794; GO:0005886; GO:0006914; GO:0007289; GO:0008022; GO:0010360; GO:0014069; GO:0015031; GO:0016020; GO:0019905; GO:0030140; GO:0030425; GO:0030695; GO:0032991; GO:0042802; GO:0042803; GO:0044325; GO:0045202; GO:0140313; GO:2000009 1554 XM_029337215.2 224 103 90 182 236 Q8IV35 3.4e-98 WD repeat-containing protein 49 Homo sapiens (Human) NA NA 1555 XM_044311628.1 11 29 20 3 22 NA NA NA NA NA NA 1556 XR_006391661.1 0 0 13 46 59 NA NA NA NA NA NA 1557 XM_029335696.2 8 0 0 0 5 P35061 5.13e-64 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 1558 XM_044327514.1 187 105 75 107 225 NA NA NA NA NA NA 1559 XM_029354800.2 0 0 0 0 7 Q09575 9.13e-24 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 1560 XM_029328918.2 273 305 267 592 484 Q9H553 6.67e-151 Alpha-1,3/1,6-mannosyltransferase ALG2 (EC 2.4.1.132) (EC 2.4.1.257) (Asparagine-linked glycosylation protein 2 homolog) (GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase) (GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase) (GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase) Homo sapiens (Human) dolichol-linked oligosaccharide biosynthetic process [GO:0006488]; oligosaccharide-lipid intermediate biosynthetic process [GO:0006490]; protein glycosylation [GO:0006486]; response to calcium ion [GO:0051592] GO:0000033; GO:0004378; GO:0005634; GO:0005737; GO:0005789; GO:0006486; GO:0006488; GO:0006490; GO:0016020; GO:0046982; GO:0047485; GO:0048306; GO:0048471; GO:0051592; GO:0102704 1561 XR_006394535.1 76 52 89 18 96 NA NA NA NA NA NA 1562 XM_029344262.2 790 691 595 1463 1318 Q9Y6X2 6.58e-139 E3 SUMO-protein ligase PIAS3 (EC 2.3.2.-) (E3 SUMO-protein transferase PIAS3) (Protein inhibitor of activated STAT protein 3) Homo sapiens (Human) negative regulation of gene expression [GO:0010629]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of gene expression [GO:0010628]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein sumoylation [GO:0033235]; protein sumoylation [GO:0016925]; regulation of transcription by RNA polymerase II [GO:0006357]; response to hormone [GO:0009725]; TNFSF11-mediated signaling pathway [GO:0071847] GO:0000122; GO:0003712; GO:0005654; GO:0005737; GO:0006357; GO:0008022; GO:0008270; GO:0009725; GO:0010628; GO:0010629; GO:0015459; GO:0016607; GO:0016925; GO:0019789; GO:0019899; GO:0030425; GO:0033234; GO:0033235; GO:0045202; GO:0045671; GO:0045838; GO:0047485; GO:0061665; GO:0071847 1563 XM_029358322.2 184 242 45 132 47 NA NA NA NA NA NA 1564 XM_029356700.2 225 248 0 0 49 Q6P2S7 1.44e-118 Putative tetratricopeptide repeat protein 41 (TPR repeat protein 41) (Grp94-neighboring nucleotidase) Homo sapiens (Human) NA GO:0005737 1565 XM_044316819.1 0 0 64 1 491 P48734 1.14e-147 Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase) Bos taurus (Bovine) apoptotic process [GO:0006915]; cell division [GO:0051301]; epithelial cell differentiation [GO:0030855]; fibroblast proliferation [GO:0048144]; G2/M transition of mitotic cell cycle [GO:0000086]; Golgi disassembly [GO:0090166]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; negative regulation of apoptotic process [GO:0043066]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of mitochondrial ATP synthesis coupled electron transport [GO:1905448]; positive regulation of protein localization to nucleus [GO:1900182]; protein localization to kinetochore [GO:0034501]; protein phosphorylation [GO:0006468]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511] GO:0000086; GO:0003682; GO:0004674; GO:0004693; GO:0005524; GO:0005634; GO:0005654; GO:0005759; GO:0005813; GO:0005829; GO:0005876; GO:0006468; GO:0006915; GO:0007095; GO:0008353; GO:0010971; GO:0018105; GO:0018107; GO:0030332; GO:0030496; GO:0030544; GO:0030855; GO:0034501; GO:0035173; GO:0042752; GO:0043066; GO:0048144; GO:0048511; GO:0051301; GO:0072686; GO:0090166; GO:0097125; GO:0106310; GO:1900182; GO:1905448 1566 XM_044318674.1 790 124 0 578 430 Q8IVV2 0 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 1567 XM_044318674.1 790 124 0 578 430 Q8IVV2 4.52e-170 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 1568 XM_044318674.1 790 124 0 578 430 Q8IVV2 1.14e-163 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 1569 XM_044318674.1 790 124 0 578 430 Q8IVV2 2.14e-154 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 1570 XM_044318674.1 790 124 0 578 430 Q8IVV2 1.23e-117 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 1571 XM_044318674.1 790 124 0 578 430 Q8IVV2 6.95e-108 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 1572 XM_044309601.1 0 1 33 0 10 NA NA NA NA NA NA 1573 XR_006395525.1 138 92 235 35 196 NA NA NA NA NA NA 1574 XM_044315643.1 3 0 5 8 25 NA NA NA NA NA NA 1575 XM_044327446.1 0 0 0 7 0 Q91ZV2 4.67e-30 Discoidin, CUB and LCCL domain-containing protein 2 (Endothelial and smooth muscle cell-derived neuropilin-like protein) Rattus norvegicus (Rat) negative regulation of cell growth [GO:0030308]; wound healing [GO:0042060] GO:0005886; GO:0009986; GO:0030308; GO:0038023; GO:0042060 1576 XM_029328179.2 37 61 72 24 17 Q91X34 2.62e-34 Bile acid-CoA:amino acid N-acyltransferase (BACAT) (BAT) (EC 2.3.1.65) (Bile acid-CoA thioesterase) (Choloyl-CoA hydrolase) (EC 3.1.2.27) (Glycine N-choloyltransferase) (Long-chain fatty-acyl-CoA hydrolase) (EC 3.1.2.2) Mus musculus (Mouse) acyl-CoA metabolic process [GO:0006637]; animal organ regeneration [GO:0031100]; bile acid biosynthetic process [GO:0006699]; bile acid conjugation [GO:0002152]; bile acid metabolic process [GO:0008206]; fatty acid metabolic process [GO:0006631]; glycine metabolic process [GO:0006544]; liver development [GO:0001889]; taurine metabolic process [GO:0019530] GO:0001889; GO:0002152; GO:0005777; GO:0005829; GO:0006544; GO:0006631; GO:0006637; GO:0006699; GO:0008206; GO:0016290; GO:0016410; GO:0019530; GO:0031100; GO:0033882; GO:0047617; GO:0047963; GO:0052815; GO:0052816; GO:0052817; GO:0102991 1577 XM_029357405.2 1006 321 437 571 698 Q6DID7 2.32e-159 Protein wntless homolog (Integral membrane protein GPR177) (Protein evenness interrupted homolog) (EVI) Mus musculus (Mouse) anterior/posterior axis specification [GO:0009948]; cementum mineralization [GO:0071529]; exocrine pancreas development [GO:0031017]; hindbrain development [GO:0030902]; intracellular protein transport [GO:0006886]; mesoderm formation [GO:0001707]; midbrain development [GO:0030901]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of Wnt protein secretion [GO:0061357]; positive regulation of Wnt signaling pathway [GO:0030177]; Wnt protein secretion [GO:0061355]; Wnt signaling pathway [GO:0016055] GO:0000139; GO:0001707; GO:0005769; GO:0005783; GO:0005789; GO:0005794; GO:0005802; GO:0005829; GO:0005886; GO:0006886; GO:0009948; GO:0012505; GO:0016055; GO:0017147; GO:0030177; GO:0030901; GO:0030902; GO:0031017; GO:0031090; GO:0031410; GO:0031852; GO:0031901; GO:0032590; GO:0032839; GO:0042802; GO:0050775; GO:0061355; GO:0061357; GO:0071529; GO:0090263 1578 XM_044307961.1 8 0 0 0 0 NA NA NA NA NA NA 1579 XM_044307575.1 40 36 11 58 31 NA NA NA NA NA NA 1580 XM_029331618.2 204 124 105 53 149 Q9H6P5 8.63e-101 Threonine aspartase 1 (Taspase-1) (EC 3.4.25.-) [Cleaved into: Threonine aspartase subunit alpha; Threonine aspartase subunit beta] Homo sapiens (Human) positive regulation of DNA-templated transcription [GO:0045893]; protein maturation [GO:0051604]; proteolysis [GO:0006508] GO:0004298; GO:0005737; GO:0006508; GO:0042802; GO:0045893; GO:0051604 1581 XM_029334449.2 0 0 0 11 0 O13018 3.51e-44 Vertebrate ancient opsin Salmo salar (Atlantic salmon) phototransduction, visible light [GO:0007603] GO:0004930; GO:0007603; GO:0009881; GO:0016020 1582 XR_006395681.1 1464 879 1125 1545 1601 Q8BV79 0 TPR and ankyrin repeat-containing protein 1 (Lupus brain antigen 1) Mus musculus (Mouse) NA NA 1583 XR_006395681.1 1464 879 1125 1545 1601 Q8BV79 0 TPR and ankyrin repeat-containing protein 1 (Lupus brain antigen 1) Mus musculus (Mouse) NA NA 1584 XR_006395681.1 1464 879 1125 1545 1601 Q8BV79 0 TPR and ankyrin repeat-containing protein 1 (Lupus brain antigen 1) Mus musculus (Mouse) NA NA 1585 XR_006395681.1 1464 879 1125 1545 1601 Q8BV79 0 TPR and ankyrin repeat-containing protein 1 (Lupus brain antigen 1) Mus musculus (Mouse) NA NA 1586 XR_006395681.1 1464 879 1125 1545 1601 Q8BV79 0 TPR and ankyrin repeat-containing protein 1 (Lupus brain antigen 1) Mus musculus (Mouse) NA NA 1587 XR_006395681.1 1464 879 1125 1545 1601 Q8BV79 0 TPR and ankyrin repeat-containing protein 1 (Lupus brain antigen 1) Mus musculus (Mouse) NA NA 1588 XM_029339812.2 287 0 0 0 0 NA NA NA NA NA NA 1589 XM_029346116.2 7248 6492 4270 6565 5453 Q5I085 0 Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (EC 3.1.3.16) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell cycle [GO:0007049]; cell division [GO:0051301]; glycogen metabolic process [GO:0005977]; regulation of cell adhesion [GO:0030155] GO:0005634; GO:0005977; GO:0007049; GO:0017018; GO:0030155; GO:0046872; GO:0050115; GO:0051301; GO:0072357 1590 XM_029336273.2 71 1 26 33 180 NA NA NA NA NA NA 1591 XM_044324210.1 2 0 0 14 16 G8XYX6 1.04e-51 Monocarboxylate transporter 8 (MCT 8) (Solute carrier family 16 member 2) Danio rerio (Zebrafish) (Brachydanio rerio) brain development [GO:0007420]; central nervous system development [GO:0007417]; chordate embryonic development [GO:0043009]; locomotion [GO:0040011]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; Schwann cell differentiation [GO:0014037]; spinal cord development [GO:0021510]; spinal cord oligodendrocyte cell differentiation [GO:0021529]; thyroid gland development [GO:0030878] GO:0007417; GO:0007420; GO:0014037; GO:0015349; GO:0016324; GO:0021510; GO:0021529; GO:0030182; GO:0030878; GO:0040011; GO:0043009; GO:0048709; GO:0070324 1592 XM_044318842.1 1877 1615 1115 1878 1624 Q8K4Z5 4.8e-117 Splicing factor 3A subunit 1 (SF3a120) Mus musculus (Mouse) mRNA cis splicing, via spliceosome [GO:0045292]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; U2-type prespliceosome assembly [GO:1903241] GO:0000398; GO:0003723; GO:0005634; GO:0005654; GO:0005681; GO:0005684; GO:0005686; GO:0006397; GO:0016607; GO:0045292; GO:0071004; GO:0071005; GO:0071013; GO:1903241 1593 XM_044318842.1 1877 1615 1115 1878 1624 Q8K4Z5 1.27e-49 Splicing factor 3A subunit 1 (SF3a120) Mus musculus (Mouse) mRNA cis splicing, via spliceosome [GO:0045292]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; U2-type prespliceosome assembly [GO:1903241] GO:0000398; GO:0003723; GO:0005634; GO:0005654; GO:0005681; GO:0005684; GO:0005686; GO:0006397; GO:0016607; GO:0045292; GO:0071004; GO:0071005; GO:0071013; GO:1903241 1594 XM_044318842.1 1877 1615 1115 1878 1624 Q8K4Z5 1.53e-34 Splicing factor 3A subunit 1 (SF3a120) Mus musculus (Mouse) mRNA cis splicing, via spliceosome [GO:0045292]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; U2-type prespliceosome assembly [GO:1903241] GO:0000398; GO:0003723; GO:0005634; GO:0005654; GO:0005681; GO:0005684; GO:0005686; GO:0006397; GO:0016607; GO:0045292; GO:0071004; GO:0071005; GO:0071013; GO:1903241 1595 XM_044321073.1 24 7 35 5 42 NA NA NA NA NA NA 1596 XM_044328361.1 0 0 31 21 1 NA NA NA NA NA NA 1597 XM_029357344.2 4489 7802 2713 5315 4730 Q9MYM7 2.82e-25 Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.86) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1) Pongo pygmaeus (Bornean orangutan) lipid metabolic process [GO:0006629]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0006629; GO:0047275 1598 XM_044307769.1 31 18 32 38 117 NA NA NA NA NA NA 1599 XM_029329450.2 63 190 43 129 161 NA NA NA NA NA NA 1600 XM_029331808.2 2032 1882 1656 1890 1927 NA NA NA NA NA NA 1601 XM_029356005.2 1084 580 691 766 371 NA NA NA NA NA NA 1602 XR_006396126.1 0 1 9 0 0 NA NA NA NA NA NA 1603 XM_029329548.2 446 559 540 732 589 R1CW23 3.2e-114 Dimethylsulfonioproprionate lyase 7 (DMSP lyase 7) (EC 4.4.1.3) (Dimethylpropiothetin dethiomethylase 7) Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi) NA GO:0047869 1604 XM_029338742.2 411 32 21 19 402 Q8QHA5 0 DNA replication ATP-dependent helicase/nuclease DNA2 (DNA replication ATP-dependent helicase-like homolog) [Includes: DNA replication nuclease DNA2 (EC 3.1.-.-); DNA replication ATP-dependent helicase DNA2 (EC 3.6.4.12)] Xenopus laevis (African clawed frog) base-excision repair [GO:0006284]; DNA double-strand break processing [GO:0000729]; DNA replication [GO:0006260]; DNA replication checkpoint signaling [GO:0000076]; DNA replication, Okazaki fragment processing [GO:0033567]; DNA replication, removal of RNA primer [GO:0043137]; double-strand break repair via single-strand annealing [GO:0045002]; mitochondrial DNA replication [GO:0006264]; positive regulation of DNA replication [GO:0045740] GO:0000076; GO:0000729; GO:0003677; GO:0003678; GO:0004518; GO:0005524; GO:0005634; GO:0005739; GO:0006260; GO:0006264; GO:0006284; GO:0016887; GO:0016890; GO:0017108; GO:0017116; GO:0033567; GO:0043137; GO:0043139; GO:0045002; GO:0045740; GO:0046872; GO:0051539 1605 XR_006395103.1 143 9 18 9 24 NA NA NA NA NA NA 1606 XM_029336203.2 311 229 171 303 292 Q38931 9.77e-32 Peptidyl-prolyl cis-trans isomerase FKBP62 (PPIase FKBP62) (EC 5.2.1.8) (70 kDa peptidyl-prolyl isomerase) (FK506-binding protein 62) (AtFKBP62) (Immunophilin FKBP62) (Peptidylprolyl isomerase ROF1) (Protein ROTAMASE FKBP 1) (Rotamase) Arabidopsis thaliana (Mouse-ear cress) cellular heat acclimation [GO:0070370]; chaperone-mediated protein folding [GO:0061077]; protein peptidyl-prolyl isomerization [GO:0000413] GO:0000413; GO:0003755; GO:0005516; GO:0005634; GO:0005737; GO:0061077; GO:0070370 1607 XM_044315492.1 11 0 15 0 74 Q6AZB8 2.95e-40 Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0004518; GO:0005634; GO:0005737; GO:0046872 1608 XM_029324301.2 91 0 14 44 0 Q3EC11 2.19e-67 Probable protein S-acyltransferase 23 (EC 2.3.1.225) (Probable palmitoyltransferase At2g14255) (Zinc finger DHHC domain-containing protein At2g14255) Arabidopsis thaliana (Mouse-ear cress) peptidyl-L-cysteine S-palmitoylation [GO:0018230]; protein targeting to membrane [GO:0006612] GO:0000139; GO:0005783; GO:0005794; GO:0006612; GO:0018230; GO:0019706 1609 XR_006391664.1 608 480 597 732 975 Q9HAR2 8.69e-76 Adhesion G protein-coupled receptor L3 (Calcium-independent alpha-latrotoxin receptor 3) (CIRL-3) (Latrophilin-3) (Lectomedin-3) Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; brain development [GO:0007420]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; G protein-coupled receptor signaling pathway [GO:0007186]; neuron migration [GO:0001764]; synapse assembly [GO:0007416] GO:0001764; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007166; GO:0007186; GO:0007189; GO:0007416; GO:0007420; GO:0016020; GO:0030246; GO:0030424; GO:0098742; GO:0098978 1610 XM_029347438.2 10 25 4 83 58 NA NA NA NA NA NA 1611 XM_029356623.2 1191 803 592 1166 1847 NA NA NA NA NA NA 1612 XM_044307012.1 26 15 6 0 20 Q803U7 2.03e-55 Exonuclease 1 (EC 3.1.-.-) (Exonuclease I) Danio rerio (Zebrafish) (Brachydanio rerio) DNA recombination [GO:0006310]; mismatch repair [GO:0006298] GO:0003677; GO:0005634; GO:0006298; GO:0006310; GO:0017108; GO:0035312; GO:0045145; GO:0046872; GO:0048256 1613 XM_044324171.1 195 106 86 130 146 P35249 1.13e-57 Replication factor C subunit 4 (Activator 1 37 kDa subunit) (A1 37 kDa subunit) (Activator 1 subunit 4) (Replication factor C 37 kDa subunit) (RF-C 37 kDa subunit) (RFC37) Homo sapiens (Human) DNA duplex unwinding [GO:0032508]; DNA repair [GO:0006281]; DNA strand elongation involved in DNA replication [GO:0006271]; DNA-templated DNA replication [GO:0006261]; positive regulation of DNA-directed DNA polymerase activity [GO:1900264] GO:0003677; GO:0005524; GO:0005634; GO:0005654; GO:0005663; GO:0006261; GO:0006271; GO:0006281; GO:0016887; GO:0031390; GO:0031391; GO:0032508; GO:1900264 1614 XM_029329346.2 3444 3361 1848 2760 3034 Q5R4D4 7.16e-101 Nucleosome assembly protein 1-like 1 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) nervous system development [GO:0007399]; nucleosome assembly [GO:0006334]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neurogenesis [GO:0050769] GO:0005634; GO:0005737; GO:0006334; GO:0007399; GO:0042470; GO:0050769; GO:2000179 1615 XM_029333670.2 67 29 45 68 35 P35384 7.3e-86 Extracellular calcium-sensing receptor (CaSR) (Parathyroid cell calcium-sensing receptor) (BoPCaR1) (PCaR1) Bos taurus (Bovine) calcium ion import [GO:0070509]; calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; detection of calcium ion [GO:0005513]; G protein-coupled receptor signaling pathway [GO:0007186]; JNK cascade [GO:0007254]; ossification [GO:0001503]; positive regulation of ATP-dependent activity [GO:0032781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; regulation of calcium ion transport [GO:0051924]; vasodilation [GO:0042311] GO:0001503; GO:0004930; GO:0005509; GO:0005513; GO:0005886; GO:0006816; GO:0006874; GO:0007186; GO:0007254; GO:0008284; GO:0010628; GO:0016597; GO:0032781; GO:0042311; GO:0042803; GO:0043679; GO:0051924; GO:0070509 1616 XM_029357451.2 0 0 162 0 24 Q80TC6 0 Zinc finger SWIM domain-containing protein 5 Mus musculus (Mouse) NA GO:0008270; GO:0031462 1617 XM_044315666.1 39 100 62 47 284 NA NA NA NA NA NA 1618 XM_044318050.1 1407 1163 571 906 760 Q53G59 0 Kelch-like protein 12 (CUL3-interacting protein 1) (DKIR homolog) (hDKIR) Homo sapiens (Human) COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; protein monoubiquitination [GO:0006513]; Wnt signaling pathway [GO:0016055] GO:0005829; GO:0006513; GO:0006888; GO:0014029; GO:0014032; GO:0016055; GO:0030127; GO:0030134; GO:0031463; GO:0034451; GO:0042802; GO:0043231; GO:0048208 1619 XM_029328947.2 1180 1043 533 1391 897 NA NA NA NA NA NA 1620 XM_029334790.2 23 204 28 125 38 NA NA NA NA NA NA 1621 XM_029325597.2 35 104 7 120 29 NA NA NA NA NA NA 1622 XR_006391290.1 52 37 51 46 78 NA NA NA NA NA NA 1623 XM_029325138.2 23 39 24 54 22 NA NA NA NA NA NA 1624 XR_006397123.1 37 21 69 15 73 NA NA NA NA NA NA 1625 XR_006392123.1 258 264 224 196 315 NA NA NA NA NA NA 1626 XM_044312622.1 137 139 53 115 95 NA NA NA NA NA NA 1627 XM_029329766.2 11 0 1 3 0 Q9R1I1 3.95e-26 Carbohydrate sulfotransferase 4 (EC 2.8.2.-) (Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 3) (GST-3) (High endothelial cells N-acetylglucosamine 6-O-sulfotransferase) (HEC-GlcNAc6ST) (L-selectin ligand sulfotransferase) (LSST) (N-acetylglucosamine 6-O-sulfotransferase 2) (GlcNAc6ST-2) (Gn6st-2) Mus musculus (Mouse) carbohydrate metabolic process [GO:0005975]; inflammatory response [GO:0006954]; leukocyte tethering or rolling [GO:0050901]; N-acetylglucosamine metabolic process [GO:0006044]; positive regulation of leukocyte tethering or rolling [GO:1903238]; protein sulfation [GO:0006477]; sulfur compound metabolic process [GO:0006790] GO:0000139; GO:0001517; GO:0005802; GO:0005975; GO:0006044; GO:0006477; GO:0006790; GO:0006954; GO:0050901; GO:1903238 1628 XR_006396666.1 67 71 19 87 16 NA NA NA NA NA NA 1629 XM_029338138.2 29 21 14 23 23 Q9NPF2 1.05e-61 Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4S-1) (C4ST-1) (C4ST1) Homo sapiens (Human) apoptotic process [GO:0006915]; carbohydrate biosynthetic process [GO:0016051]; chondrocyte development [GO:0002063]; chondroitin sulfate biosynthetic process [GO:0030206]; developmental growth [GO:0048589]; embryonic digit morphogenesis [GO:0042733]; embryonic viscerocranium morphogenesis [GO:0048703]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; polysaccharide localization [GO:0033037]; post-anal tail morphogenesis [GO:0036342]; post-embryonic development [GO:0009791]; proteoglycan biosynthetic process [GO:0030166]; regulation of cell population proliferation [GO:0042127]; respiratory gaseous exchange by respiratory system [GO:0007585]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0000139; GO:0001537; GO:0001701; GO:0002063; GO:0006915; GO:0007179; GO:0007585; GO:0008146; GO:0009791; GO:0016020; GO:0016051; GO:0030166; GO:0030206; GO:0030512; GO:0033037; GO:0036342; GO:0042127; GO:0042733; GO:0043066; GO:0047756; GO:0048589; GO:0048703; GO:0050659 1630 XM_029331977.2 0 27 0 0 0 B0G143 7.7e-82 Mitochondrial substrate carrier family protein ucpB (Solute carrier family 25 member 30 homolog) (Uncoupler protein B) Dictyostelium discoideum (Social amoeba) mitochondrial transport [GO:0006839] GO:0005743; GO:0006839; GO:0022857 1631 XM_044320098.1 1060 892 464 780 112 NA NA NA NA NA NA 1632 XM_044318923.1 0 0 210 0 0 O54857 8.81e-110 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (EC 3.1.3.16) (EC 3.1.3.48) (EC 3.1.3.67) (Phosphatase and tensin homolog) Rattus norvegicus (Rat) adult behavior [GO:0030534]; aging [GO:0007568]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; B cell proliferation [GO:0042100]; brain morphogenesis [GO:0048854]; canonical Wnt signaling pathway [GO:0060070]; cardiac muscle tissue development [GO:0048738]; cell migration [GO:0016477]; cell motility [GO:0048870]; cell population proliferation [GO:0008283]; cellular response to decreased oxygen levels [GO:0036294]; cellular response to electrical stimulus [GO:0071257]; cellular response to ethanol [GO:0071361]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to leptin stimulus [GO:0044320]; cellular response to nerve growth factor stimulus [GO:1990090]; central nervous system development [GO:0007417]; central nervous system myelin maintenance [GO:0032286]; central nervous system neuron axonogenesis [GO:0021955]; dendritic spine morphogenesis [GO:0060997]; dentate gyrus development [GO:0021542]; dephosphorylation [GO:0016311]; endothelial cell migration [GO:0043542]; forebrain morphogenesis [GO:0048853]; heart development [GO:0007507]; inositol phosphate dephosphorylation [GO:0046855]; learning or memory [GO:0007611]; locomotor rhythm [GO:0045475]; locomotory behavior [GO:0007626]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; male mating behavior [GO:0060179]; maternal behavior [GO:0042711]; memory [GO:0007613]; multicellular organismal response to stress [GO:0033555]; myelination [GO:0042552]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axon regeneration [GO:0048681]; negative regulation of axonogenesis [GO:0050771]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell cycle G1/S phase transition [GO:1902807]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of cellular senescence [GO:2000773]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of defense response to bacterium [GO:1900425]; negative regulation of dendrite extension [GO:1903860]; negative regulation of dendritic spine morphogenesis [GO:0061002]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of keratinocyte migration [GO:0051548]; negative regulation of myelination [GO:0031642]; negative regulation of neuron projection development [GO:0010977]; negative regulation of organ growth [GO:0046621]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of phagocytosis [GO:0050765]; negative regulation of phagocytosis, engulfment [GO:0060101]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of ribosome biogenesis [GO:0090071]; negative regulation of signaling receptor activity [GO:2000272]; negative regulation of synaptic vesicle clustering [GO:2000808]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of vascular associated smooth muscle cell proliferation [GO:1904706]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; neuron projection development [GO:0031175]; neuron-neuron synaptic transmission [GO:0007270]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol dephosphorylation [GO:0046856]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of TRAIL-activated apoptotic signaling pathway [GO:1903984]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; postsynaptic density assembly [GO:0097107]; prepulse inhibition [GO:0060134]; presynaptic membrane assembly [GO:0097105]; prostate gland growth [GO:0060736]; protein dephosphorylation [GO:0006470]; protein kinase B signaling [GO:0043491]; protein stabilization [GO:0050821]; regulation of axon regeneration [GO:0048679]; regulation of B cell apoptotic process [GO:0002902]; regulation of cell cycle [GO:0051726]; regulation of cellular component size [GO:0032535]; regulation of cellular localization [GO:0060341]; regulation of macrophage apoptotic process [GO:2000109]; regulation of myeloid cell apoptotic process [GO:0033032]; regulation of neuron projection development [GO:0010975]; regulation of protein kinase B signaling [GO:0051896]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to activity [GO:0014823]; response to arsenic-containing substance [GO:0046685]; response to ATP [GO:0033198]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to glucose [GO:0009749]; response to inorganic substance [GO:0010035]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to xenobiotic stimulus [GO:0009410]; response to zinc ion [GO:0010043]; rhythmic synaptic transmission [GO:0060024]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; synapse maturation [GO:0060074]; T cell proliferation [GO:0042098] GO:0001525; GO:0001933; GO:0002902; GO:0004438; GO:0004721; GO:0004722; GO:0004725; GO:0005161; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0005886; GO:0006470; GO:0006915; GO:0007270; GO:0007416; GO:0007417; GO:0007507; GO:0007568; GO:0007584; GO:0007611; GO:0007613; GO:0007626; GO:0008138; GO:0008283; GO:0008284; GO:0008285; GO:0009410; GO:0009749; GO:0009898; GO:0010033; GO:0010035; GO:0010043; GO:0010628; GO:0010666; GO:0010719; GO:0010975; GO:0010977; GO:0010997; GO:0014065; GO:0014069; GO:0014070; GO:0014823; GO:0016311; GO:0016314; GO:0016324; GO:0016477; GO:0016605; GO:0016791; GO:0017018; GO:0019899; GO:0019901; GO:0021542; GO:0021955; GO:0030165; GO:0030336; GO:0030534; GO:0030889; GO:0031175; GO:0031642; GO:0031647; GO:0032228; GO:0032286; GO:0032355; GO:0032535; GO:0032869; GO:0033032; GO:0033137; GO:0033198; GO:0033555; GO:0035176; GO:0035255; GO:0035749; GO:0036294; GO:0042098; GO:0042100; GO:0042130; GO:0042552; GO:0042711; GO:0042802; GO:0042995; GO:0043005; GO:0043065; GO:0043066; GO:0043197; GO:0043220; GO:0043491; GO:0043542; GO:0044320; GO:0045211; GO:0045471; GO:0045475; GO:0045666; GO:0045736; GO:0045786; GO:0045792; GO:0046621; GO:0046685; GO:0046855; GO:0046856; GO:0048008; GO:0048679; GO:0048681; GO:0048738; GO:0048853; GO:0048854; GO:0048870; GO:0050680; GO:0050765; GO:0050771; GO:0050821; GO:0051091; GO:0051548; GO:0051717; GO:0051726; GO:0051800; GO:0051895; GO:0051896; GO:0051898; GO:0060024; GO:0060044; GO:0060070; GO:0060074; GO:0060101; GO:0060134; GO:0060179; GO:0060291; GO:0060292; GO:0060341; GO:0060736; GO:0060997; GO:0061002; GO:0070373; GO:0070374; GO:0071257; GO:0071361; GO:0071456; GO:0090071; GO:0090394; GO:0097105; GO:0097107; GO:0099524; GO:1900425; GO:1901017; GO:1902807; GO:1903690; GO:1903860; GO:1903984; GO:1904668; GO:1904706; GO:1990090; GO:1990314; GO:1990381; GO:1990782; GO:2000060; GO:2000109; GO:2000134; GO:2000272; GO:2000463; GO:2000773; GO:2000808; GO:2001235 1633 XM_029347161.2 282 106 0 0 0 P70426 2.22e-37 GTP-binding protein Rit1 (EC 3.6.5.2) (Ras-like protein expressed in many tissues) (Ras-like without CAAX protein 1) Mus musculus (Mouse) Ras protein signal transduction [GO:0007265] GO:0003924; GO:0003925; GO:0005516; GO:0005525; GO:0005886; GO:0007265; GO:0019003 1634 XM_044327775.1 8 2 141 113 411 NA NA NA NA NA NA 1635 XM_029323990.2 531 189 170 354 920 Q27433 2.49e-121 Mechanosensory protein 2 Caenorhabditis elegans detection of mechanical stimulus involved in sensory perception of touch [GO:0050976]; mechanosensory behavior [GO:0007638]; positive regulation of detection of mechanical stimulus involved in sensory perception of touch [GO:1905789]; positive regulation of mechanosensory behavior [GO:1905792]; potassium ion transport [GO:0006813]; response to mechanical stimulus [GO:0009612] GO:0005272; GO:0005886; GO:0006813; GO:0007638; GO:0009612; GO:0015485; GO:0032589; GO:0043005; GO:0050976; GO:1905789; GO:1905792 1636 XM_029351188.2 47 21 45 26 57 Q92113 1.27e-88 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Squalus acanthias (Spiny dogfish) steroid biosynthetic process [GO:0006694] GO:0004508; GO:0005506; GO:0006694; GO:0016020; GO:0020037; GO:0047442 1637 XM_029349716.2 23 77 2 10 4 NA NA NA NA NA NA 1638 XM_044311174.1 747 586 364 927 895 A6QLT2 1.7e-101 Myotubularin-related protein 2 (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64) Bos taurus (Bovine) inositol phosphate dephosphorylation [GO:0046855]; myelin assembly [GO:0032288]; negative regulation of myelination [GO:0031642]; neuron development [GO:0048666]; phosphatidylinositol dephosphorylation [GO:0046856]; regulation of phosphatidylinositol dephosphorylation [GO:0060304] GO:0004438; GO:0005634; GO:0005774; GO:0005829; GO:0030424; GO:0031642; GO:0031901; GO:0032288; GO:0042802; GO:0046855; GO:0046856; GO:0048471; GO:0048666; GO:0052629; GO:0060304 1639 XM_029336116.2 875 1987 90 345 14 NA NA NA NA NA NA 1640 XM_044328618.1 240 5 19 0 0 A0A0R4IBK5 0 E3 ubiquitin-protein ligase rnf213-alpha (EC 2.3.2.27) (EC 3.6.4.-) (E3 ubiquitin-lipopolysaccharide ligase rnf213-alpha) (EC 2.3.2.-) (Mysterin-A) (Mysterin-alpha) (RING finger protein 213-A) (RING finger protein 213-alpha) Danio rerio (Zebrafish) (Brachydanio rerio) blood circulation [GO:0008015]; defense response to bacterium [GO:0042742]; immune system process [GO:0002376]; lipid droplet formation [GO:0140042]; lipid ubiquitination [GO:0120323]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein K63-linked ubiquitination [GO:0070534]; regulation of lipid metabolic process [GO:0019216]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]; xenophagy [GO:0098792] GO:0002040; GO:0002376; GO:0004842; GO:0005524; GO:0005730; GO:0005811; GO:0005829; GO:0006511; GO:0008015; GO:0016887; GO:0019216; GO:0042742; GO:0046872; GO:0061630; GO:0070534; GO:0098792; GO:0120323; GO:0140042; GO:2000051 1641 XM_044328618.1 240 5 19 0 0 A0A0R4IBK5 1.36e-87 E3 ubiquitin-protein ligase rnf213-alpha (EC 2.3.2.27) (EC 3.6.4.-) (E3 ubiquitin-lipopolysaccharide ligase rnf213-alpha) (EC 2.3.2.-) (Mysterin-A) (Mysterin-alpha) (RING finger protein 213-A) (RING finger protein 213-alpha) Danio rerio (Zebrafish) (Brachydanio rerio) blood circulation [GO:0008015]; defense response to bacterium [GO:0042742]; immune system process [GO:0002376]; lipid droplet formation [GO:0140042]; lipid ubiquitination [GO:0120323]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein K63-linked ubiquitination [GO:0070534]; regulation of lipid metabolic process [GO:0019216]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]; xenophagy [GO:0098792] GO:0002040; GO:0002376; GO:0004842; GO:0005524; GO:0005730; GO:0005811; GO:0005829; GO:0006511; GO:0008015; GO:0016887; GO:0019216; GO:0042742; GO:0046872; GO:0061630; GO:0070534; GO:0098792; GO:0120323; GO:0140042; GO:2000051 1642 XM_044319745.1 534 336 209 415 214 NA NA NA NA NA NA 1643 XR_006392372.1 59 7 17 498 55 NA NA NA NA NA NA 1644 XM_029333304.2 0 0 3 0 48 NA NA NA NA NA NA 1645 XM_029343115.2 159 55 140 153 307 Q5REM8 2.8e-21 Transmembrane protein 205 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0016020 1646 XM_029350591.2 1279 96 116 640 128 Q6XP49 4.92e-74 Zinc finger protein GLIS3 (GLI-similar 3) Mus musculus (Mouse) negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366] GO:0000122; GO:0000977; GO:0000978; GO:0000981; GO:0001227; GO:0001228; GO:0003677; GO:0003700; GO:0005634; GO:0006357; GO:0006366; GO:0045944; GO:0046872 1647 XM_044309880.1 5 0 3 5 62 NA NA NA NA NA NA 1648 XM_044308178.1 0 0 140 0 336 Q9BTX1 4.49e-83 Nucleoporin NDC1 (hNDC1) (Transmembrane protein 48) Homo sapiens (Human) homologous chromosome pairing at meiosis [GO:0007129]; mRNA transport [GO:0051028]; nuclear pore complex assembly [GO:0051292]; nuclear pore localization [GO:0051664]; nuclear pore organization [GO:0006999]; nucleocytoplasmic transport [GO:0006913]; protein transport [GO:0015031]; spermatogenesis [GO:0007283] GO:0005635; GO:0005643; GO:0005737; GO:0005886; GO:0006913; GO:0006999; GO:0007129; GO:0007283; GO:0015031; GO:0015629; GO:0016020; GO:0017056; GO:0030674; GO:0031965; GO:0051028; GO:0051292; GO:0051664; GO:0070762 1649 XM_029331057.2 0 93 41 0 34 Q7SY75 8.03e-63 Neurocalcin-delta Xenopus laevis (African clawed frog) NA GO:0005509 1650 XM_029356686.2 10107 10513 6976 8886 6959 Q5ZML7 2.7e-27 Lysosomal-associated transmembrane protein 4A Gallus gallus (Chicken) NA GO:0005765; GO:0012505 1651 XM_029329490.2 320 252 175 259 248 Q4V7Z0 1.46e-128 GPN-loop GTPase 3 (ATP-binding domain 1 family member C) Xenopus laevis (African clawed frog) NA GO:0005525; GO:0016787 1652 XR_006391425.1 12 1 4 0 11 NA NA NA NA NA NA 1653 XM_029326867.2 0 45 93 18 86 O54853 1.11e-148 Potassium voltage-gated channel subfamily H member 6 (Ether-a-go-go-related gene potassium channel 2) (ERG-2) (Eag-related protein 2) (Ether-a-go-go-related protein 2) (Voltage-gated potassium channel subunit Kv11.2) Rattus norvegicus (Rat) membrane repolarization during action potential [GO:0086011]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307] GO:0005242; GO:0005249; GO:0005267; GO:0005886; GO:0006813; GO:0034765; GO:0042391; GO:0044877; GO:0060307; GO:0071805; GO:0086011; GO:0086091 1654 XR_006392961.1 41 2 25 5 151 NA NA NA NA NA NA 1655 XR_006391427.1 17 24 1 6 3 NA NA NA NA NA NA 1656 XM_029355416.2 778 794 702 902 820 Q15061 8.85e-121 WD repeat-containing protein 43 (U3 small nucleolar RNA-associated protein 5 homolog) Homo sapiens (Human) maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; positive regulation of rRNA processing [GO:2000234]; positive regulation of transcription by RNA polymerase I [GO:0045943]; regulation of stem cell population maintenance [GO:2000036]; regulation of transcription elongation by RNA polymerase II [GO:0034243] GO:0000462; GO:0000785; GO:0000993; GO:0001650; GO:0003711; GO:0003723; GO:0005654; GO:0005730; GO:0034243; GO:0045943; GO:2000036; GO:2000234 1657 XM_029345768.2 3172 1497 83 442 1452 Q9UHD2 1.08e-143 Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1) Homo sapiens (Human) activation of innate immune response [GO:0002218]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; dendritic cell proliferation [GO:0044565]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of gene expression [GO:0010629]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of macroautophagy [GO:0016239]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of xenophagy [GO:1904417]; protein phosphorylation [GO:0006468]; regulation of neuron death [GO:1901214]; regulation of type I interferon production [GO:0032479]; response to virus [GO:0009615]; type I interferon-mediated signaling pathway [GO:0060337] GO:0002218; GO:0003676; GO:0004672; GO:0004674; GO:0005524; GO:0005654; GO:0005737; GO:0005829; GO:0006468; GO:0006954; GO:0007249; GO:0009615; GO:0010629; GO:0016239; GO:0018105; GO:0018107; GO:0019903; GO:0032479; GO:0032481; GO:0032727; GO:0032728; GO:0033138; GO:0042802; GO:0043123; GO:0043231; GO:0044565; GO:0045087; GO:0045944; GO:0050830; GO:0051219; GO:0051607; GO:0060337; GO:0060340; GO:0106310; GO:1901214; GO:1902554; GO:1904417 1658 XM_029345393.2 533 380 360 593 536 NA NA NA NA NA NA 1659 XM_029351706.2 1031 945 666 1307 989 Q922K7 8.26e-180 Probable 28S rRNA (cytosine-C(5))-methyltransferase (EC 2.1.1.-) (Nucleolar protein 1) (Nucleolar protein 2 homolog) (Proliferating-cell nucleolar antigen p120) (Proliferation-associated nucleolar protein p120) Mus musculus (Mouse) blastocyst formation [GO:0001825]; maturation of LSU-rRNA [GO:0000470]; positive regulation of cell population proliferation [GO:0008284]; regulation of signal transduction by p53 class mediator [GO:1901796]; ribosomal large subunit assembly [GO:0000027]; RNA methylation [GO:0001510]; rRNA base methylation [GO:0070475] GO:0000027; GO:0000470; GO:0001510; GO:0001825; GO:0003723; GO:0005730; GO:0008284; GO:0009383; GO:0070475; GO:1901796 1660 XM_029350965.2 1839 653 666 892 234 Q5R941 5.22e-29 Peptidyl-prolyl cis-trans isomerase FKBP14 (PPIase FKBP14) (EC 5.2.1.8) (FK506-binding protein 14) (FKBP-14) (Rotamase) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003755; GO:0005509; GO:0005788 1661 XM_029338675.2 308 449 306 357 340 NA NA NA NA NA NA 1662 XR_006391473.1 26 0 11 1 0 NA NA NA NA NA NA 1663 XM_044306903.1 190 158 106 270 228 Q54CI5 4.64e-25 DPH4 homolog (DnaJ homolog subfamily C member 24) Dictyostelium discoideum (Social amoeba) peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]; tRNA wobble uridine modification [GO:0002098] GO:0001671; GO:0002098; GO:0005634; GO:0005829; GO:0017183; GO:0046872 1664 XR_006397179.1 0 0 7 0 21 NA NA NA NA NA NA 1665 XM_029337128.2 423 131 535 346 328 NA NA NA NA NA NA 1666 XM_044308292.1 322 312 180 479 456 Q9UGU5 1.63e-36 HMG domain-containing protein 4 (HMG box-containing protein 4) (High mobility group protein 2-like 1) (Protein HMGBCG) Homo sapiens (Human) endosome to lysosome transport [GO:0008333]; negative regulation of Wnt signaling pathway [GO:0030178]; Wnt signaling pathway [GO:0016055] GO:0003677; GO:0008333; GO:0016055; GO:0016589; GO:0030178; GO:0042802 1667 XM_029343606.2 2516 1718 490 3179 2006 NA NA NA NA NA NA 1668 XM_044312710.1 183 217 92 137 104 NA NA NA NA NA NA 1669 XM_044308584.1 29 27 21 4 48 NA NA NA NA NA NA 1670 XM_029358584.2 1073 762 618 130 734 Q3KR59 1.11e-109 Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.4.19.12) (Deubiquitinating enzyme 10) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) Rattus norvegicus (Rat) autophagy [GO:0006914]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to interleukin-1 [GO:0071347]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA repair [GO:0006281]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; protein deubiquitination [GO:0016579]; regulation of autophagy [GO:0010506]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0002039; GO:0004197; GO:0004843; GO:0005634; GO:0005737; GO:0005769; GO:0005829; GO:0006281; GO:0006511; GO:0006914; GO:0006974; GO:0010506; GO:0016579; GO:0030330; GO:0032991; GO:0043124; GO:0044325; GO:0071347 1671 XM_044313187.1 128 125 121 120 174 NA NA NA NA NA NA 1672 XM_044316759.1 1487 1094 819 1692 1787 A5PJW8 0 NA NA NA NA 1673 XM_044325768.1 1 0 15 7 0 NA NA NA NA NA NA 1674 XM_044306856.1 0 8 0 0 0 NA NA NA NA NA NA 1675 XM_044307283.1 3437 2178 2275 2287 3360 P57747 4.55e-110 V-type proton ATPase subunit D (V-ATPase subunit D) (Vacuolar proton pump subunit D) Suberites domuncula (Sponge) NA GO:0046961 1676 XM_029350182.2 198 88 91 192 229 NA NA NA NA NA NA 1677 XM_029357131.2 190 122 81 121 128 Q6NYX8 2.4e-76 PITH domain-containing protein 1 Danio rerio (Zebrafish) (Brachydanio rerio) positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of megakaryocyte differentiation [GO:0045654] GO:0005634; GO:0005737; GO:0045654; GO:0045893 1678 XM_044322368.1 12 10 1 13 13 NA NA NA NA NA NA 1679 XM_029330238.2 2522 2500 1774 4222 1756 Q28BT4 1.58e-47 Calumenin Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005509; GO:0005576; GO:0005789; GO:0005794; GO:0033018; GO:0042470 1680 XM_044323969.1 0 7 0 6 17 NA NA NA NA NA NA 1681 XM_029338010.2 915 392 590 375 281 Q9Y385 6.01e-90 Ubiquitin-conjugating enzyme E2 J1 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme J1) (Non-canonical ubiquitin-conjugating enzyme 1) (NCUBE-1) (Yeast ubiquitin-conjugating enzyme UBC6 homolog E) (HsUBC6e) Homo sapiens (Human) negative regulation of retrograde protein transport, ER to cytosol [GO:1904153]; protein N-linked glycosylation via asparagine [GO:0018279]; protein polyubiquitination [GO:0000209]; regulation of macrophage cytokine production [GO:0010935]; regulation of tumor necrosis factor production [GO:0032680]; spermatid development [GO:0007286]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0000209; GO:0005524; GO:0005634; GO:0005789; GO:0007286; GO:0010935; GO:0018279; GO:0030433; GO:0031625; GO:0032680; GO:0061631; GO:1904153 1682 XM_044316362.1 61 34 48 45 50 NA NA NA NA NA NA 1683 XM_044321234.1 0 0 0 0 62 NA NA NA NA NA NA 1684 XR_006396900.1 0 6 0 0 0 NA NA NA NA NA NA 1685 XM_044325858.1 74 18 83 165 37 Q20191 1.49e-45 Zinc metalloproteinase nas-13 (EC 3.4.24.-) (Nematode astacin 13) Caenorhabditis elegans proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0006508; GO:0008270 1686 XM_044322963.1 1430 1147 945 1591 1586 A0JNC2 9.6e-38 R3H domain-containing protein 2 Bos taurus (Bovine) NA GO:0003676; GO:0005634 1687 XM_044327103.1 5 0 6 0 15 NA NA NA NA NA NA 1688 XR_006397177.1 0 0 28 0 53 NA NA NA NA NA NA 1689 XM_029331347.2 29 51 28 0 41 P52569 2.22e-124 Cationic amino acid transporter 2 (CAT-2) (CAT2) (Low affinity cationic amino acid transporter 2) (Solute carrier family 7 member 2) Homo sapiens (Human) amino acid import across plasma membrane [GO:0089718]; amino acid transport [GO:0006865]; L-alpha-amino acid transmembrane transport [GO:1902475]; L-amino acid transport [GO:0015807]; L-arginine import across plasma membrane [GO:0097638]; L-arginine transmembrane transport [GO:1903826]; L-ornithine transmembrane transport [GO:1903352]; transport across blood-brain barrier [GO:0150104] GO:0000064; GO:0005886; GO:0006865; GO:0015171; GO:0015174; GO:0015179; GO:0015189; GO:0015807; GO:0030054; GO:0061459; GO:0089718; GO:0097638; GO:0150104; GO:1902475; GO:1903352; GO:1903826 1690 XR_006392965.1 41 2 25 5 151 NA NA NA NA NA NA 1691 XM_044326700.1 38 0 2 0 0 NA NA NA NA NA NA 1692 XR_003826876.2 30 35 18 19 32 NA NA NA NA NA NA 1693 XM_044316583.1 5494 2986 2484 3605 4100 Q27954 0 Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP) (HEP-COP) (HEPCOP) [Cleaved into: Xenin (Xenopsin-related peptide); Proxenin] Bos taurus (Bovine) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] GO:0000139; GO:0005179; GO:0005198; GO:0005576; GO:0006886; GO:0006888; GO:0006890; GO:0006891; GO:0030126 1694 XM_044317979.1 4302 2026 1824 2869 2412 A7S4N4 3.19e-171 Probable serine incorporator Nematostella vectensis (Starlet sea anemone) phospholipid biosynthetic process [GO:0008654] GO:0005789; GO:0008654; GO:0016020 1695 XM_029346218.2 326 95 64 164 235 NA NA NA NA NA NA 1696 XR_006397769.1 0 27 0 0 0 NA NA NA NA NA NA 1697 XM_044321571.1 57 102 61 262 255 Q15477 0 SKI2 subunit of superkiller complex protein (Helicase SKI2W) (Ski2) (EC 3.6.4.13) (Helicase-like protein) (HLP) Homo sapiens (Human) nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay [GO:0070478]; RNA catabolic process [GO:0006401] GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005829; GO:0006401; GO:0016887; GO:0055087; GO:0070478 1698 XM_044307277.1 242 57 105 217 138 B5DF45 1.12e-57 TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6) Rattus norvegicus (Rat) activation of NF-kappaB-inducing kinase activity [GO:0007250]; activation of protein kinase activity [GO:0032147]; animal organ morphogenesis [GO:0009887]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; bone remodeling [GO:0046849]; bone resorption [GO:0045453]; cell development [GO:0048468]; cellular response to cytokine stimulus [GO:0071345]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-17-mediated signaling pathway [GO:0097400]; JNK cascade [GO:0007254]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin production [GO:0002637]; response to interleukin-1 [GO:0070555]; response to ischemia [GO:0002931]; signal transduction [GO:0007165]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000122; GO:0000209; GO:0001503; GO:0001701; GO:0001843; GO:0002637; GO:0002726; GO:0002931; GO:0004842; GO:0005164; GO:0005634; GO:0005737; GO:0005811; GO:0005829; GO:0005886; GO:0005938; GO:0006955; GO:0006974; GO:0007165; GO:0007249; GO:0007250; GO:0007254; GO:0008270; GO:0009887; GO:0009898; GO:0016567; GO:0019221; GO:0019886; GO:0019901; GO:0030316; GO:0031435; GO:0031624; GO:0031625; GO:0031666; GO:0031996; GO:0032147; GO:0032735; GO:0032743; GO:0032755; GO:0032813; GO:0032991; GO:0033209; GO:0035631; GO:0042088; GO:0042102; GO:0042475; GO:0042802; GO:0042826; GO:0042981; GO:0043011; GO:0043122; GO:0043123; GO:0043422; GO:0043507; GO:0045453; GO:0045672; GO:0045892; GO:0045944; GO:0046330; GO:0046849; GO:0047485; GO:0048468; GO:0048471; GO:0048661; GO:0050852; GO:0051091; GO:0051092; GO:0051865; GO:0061630; GO:0070498; GO:0070534; GO:0070555; GO:0071222; GO:0071345; GO:0097400; GO:1901224; GO:1904996; GO:2000679 1699 XM_029338023.2 0 14 0 50 0 NA NA NA NA NA NA 1700 XM_044309208.1 0 0 0 0 12 NA NA NA NA NA NA 1701 XM_029336408.2 84 33 21 122 31 Q9UKN7 0 Unconventional myosin-XV (Unconventional myosin-15) Homo sapiens (Human) actin filament organization [GO:0007015]; inner ear morphogenesis [GO:0042472]; locomotory behavior [GO:0007626]; response to light stimulus [GO:0009416]; sensory perception of sound [GO:0007605]; vesicle transport along actin filament [GO:0030050] GO:0000146; GO:0005516; GO:0005524; GO:0005737; GO:0007015; GO:0007605; GO:0007626; GO:0009416; GO:0015629; GO:0016459; GO:0030050; GO:0031982; GO:0032420; GO:0042472; GO:0051015; GO:0070062; GO:0098858 1702 XM_029336408.2 84 33 21 122 31 Q9UKN7 2.12e-128 Unconventional myosin-XV (Unconventional myosin-15) Homo sapiens (Human) actin filament organization [GO:0007015]; inner ear morphogenesis [GO:0042472]; locomotory behavior [GO:0007626]; response to light stimulus [GO:0009416]; sensory perception of sound [GO:0007605]; vesicle transport along actin filament [GO:0030050] GO:0000146; GO:0005516; GO:0005524; GO:0005737; GO:0007015; GO:0007605; GO:0007626; GO:0009416; GO:0015629; GO:0016459; GO:0030050; GO:0031982; GO:0032420; GO:0042472; GO:0051015; GO:0070062; GO:0098858 1703 XM_029357753.2 151 121 35 97 124 Q96LR5 1.26e-94 Ubiquitin-conjugating enzyme E2 E2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme E2) (UbcH8) (Ubiquitin carrier protein E2) (Ubiquitin-protein ligase E2) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; ISG15-protein conjugation [GO:0032020]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; protein K11-linked ubiquitination [GO:0070979]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209] GO:0000209; GO:0004842; GO:0005524; GO:0005634; GO:0006974; GO:0032020; GO:0042296; GO:0061631; GO:0070534; GO:0070936; GO:0070979; GO:1900087 1704 XR_006396295.1 0 31 0 0 131 NA NA NA NA NA NA 1705 XM_029335598.2 0 28 74 269 38 O70521 3.43e-37 Regulator of G-protein signaling 19 (RGS19) (G-alpha-interacting protein) (GAIP) Rattus norvegicus (Rat) negative regulation of signal transduction [GO:0009968]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; response to ethanol [GO:0045471] GO:0000139; GO:0001965; GO:0005096; GO:0005737; GO:0005903; GO:0008277; GO:0009968; GO:0016020; GO:0030136; GO:0045121; GO:0045471 1706 XM_029357733.2 345 0 50 121 8 Q8AYG3 6.98e-92 Dual specificity protein kinase Ttk (EC 2.7.12.1) (Mitotic checkpoint serine/threonine-protein kinase Mps1) (Monopolar spindle protein 1) (Protein nightcap) Danio rerio (Zebrafish) (Brachydanio rerio) anatomical structure homeostasis [GO:0060249]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; female meiosis chromosome segregation [GO:0016321]; fin regeneration [GO:0031101]; male meiosis chromosome segregation [GO:0007060]; meiotic spindle assembly checkpoint signaling [GO:0033316]; mitotic spindle assembly checkpoint signaling [GO:0007094]; negative regulation of exit from mitosis [GO:0001100]; peptidyl-serine phosphorylation [GO:0018105]; protein localization to kinetochore [GO:0034501]; tissue regeneration [GO:0042246] GO:0000776; GO:0001100; GO:0004674; GO:0004712; GO:0004713; GO:0005524; GO:0005634; GO:0007059; GO:0007060; GO:0007094; GO:0016321; GO:0018105; GO:0031101; GO:0033316; GO:0034501; GO:0042246; GO:0046872; GO:0051301; GO:0060249; GO:0106310 1707 XR_006395828.1 0 0 0 0 44 NA NA NA NA NA NA 1708 XM_044312061.1 0 9 0 0 0 NA NA NA NA NA NA 1709 XM_029331325.2 8 4 0 0 41 NA NA NA NA NA NA 1710 XM_044319358.1 90 79 59 83 35 NA NA NA NA NA NA 1711 XM_044320369.1 0 6 0 0 2 NA NA NA NA NA NA 1712 XR_006391280.1 37 10 11 25 12 NA NA NA NA NA NA 1713 XM_044314854.1 2 16 0 5 6 NA NA NA NA NA NA 1714 XM_044308901.1 14 2 4 18 8 NA NA NA NA NA NA 1715 XR_006394740.1 58 0 0 0 0 NA NA NA NA NA NA 1716 XM_044325327.1 54 25 71 98 94 A6QLU6 4.22e-69 Adhesion G-protein coupled receptor D1 (G-protein coupled receptor 133) Bos taurus (Bovine) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0005886; GO:0007166; GO:0007186; GO:0007189 1717 XM_044312519.1 0 0 0 4 9 NA NA NA NA NA NA 1718 XM_044327978.1 81 50 0 0 179 NA NA NA NA NA NA 1719 XM_044315031.1 215 0 254 214 163 NA NA NA NA NA NA 1720 XM_029335808.2 182 0 131 52 0 Q68FX0 2.65e-132 Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial (Isocitric dehydrogenase subunit beta) (NAD(+)-specific ICDH subunit beta) Rattus norvegicus (Rat) 2-oxoglutarate metabolic process [GO:0006103]; isocitrate metabolic process [GO:0006102]; NADH metabolic process [GO:0006734]; tricarboxylic acid cycle [GO:0006099] GO:0000287; GO:0004449; GO:0005739; GO:0005962; GO:0006099; GO:0006102; GO:0006103; GO:0006734; GO:0051287 1721 XM_029352113.2 731 622 184 3504 2108 Q5E9J9 1.42e-78 STE20-related kinase adapter protein alpha (STRAD alpha) (STE20-related adapter protein) Bos taurus (Bovine) activation of protein kinase activity [GO:0032147]; cell cycle [GO:0007049]; protein export from nucleus [GO:0006611]; protein phosphorylation [GO:0006468] GO:0004672; GO:0005524; GO:0005634; GO:0005737; GO:0006468; GO:0006611; GO:0007049; GO:0030295; GO:0032147; GO:0043539; GO:1902554 1722 XM_029326851.2 398 266 179 256 283 D3YXG0 3.62e-80 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 1723 XM_029356823.2 11 0 38 15 5 NA NA NA NA NA NA 1724 XM_044311551.1 1 0 0 8 0 NA NA NA NA NA NA 1725 XM_044326578.1 2096 1731 1342 2735 2397 Q00174 5.45e-169 Laminin subunit alpha (Laminin A chain) Drosophila melanogaster (Fruit fly) animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; basement membrane organization [GO:0071711]; cell adhesion mediated by integrin [GO:0033627]; dorsal trunk growth, open tracheal system [GO:0035001]; heart development [GO:0007507]; melanotic encapsulation of foreign target [GO:0035011]; mesoderm development [GO:0007498]; negative regulation of synaptic assembly at neuromuscular junction [GO:0045886]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888] GO:0005102; GO:0005576; GO:0005604; GO:0007411; GO:0007498; GO:0007507; GO:0008021; GO:0009887; GO:0009888; GO:0030155; GO:0030334; GO:0030424; GO:0033627; GO:0034446; GO:0035001; GO:0035011; GO:0036062; GO:0045886; GO:0045995; GO:0062023; GO:0071711 1726 XM_044326578.1 2096 1731 1342 2735 2397 Q00174 3.48e-64 Laminin subunit alpha (Laminin A chain) Drosophila melanogaster (Fruit fly) animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; basement membrane organization [GO:0071711]; cell adhesion mediated by integrin [GO:0033627]; dorsal trunk growth, open tracheal system [GO:0035001]; heart development [GO:0007507]; melanotic encapsulation of foreign target [GO:0035011]; mesoderm development [GO:0007498]; negative regulation of synaptic assembly at neuromuscular junction [GO:0045886]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888] GO:0005102; GO:0005576; GO:0005604; GO:0007411; GO:0007498; GO:0007507; GO:0008021; GO:0009887; GO:0009888; GO:0030155; GO:0030334; GO:0030424; GO:0033627; GO:0034446; GO:0035001; GO:0035011; GO:0036062; GO:0045886; GO:0045995; GO:0062023; GO:0071711 1727 XM_044326578.1 2096 1731 1342 2735 2397 Q00174 2.82e-36 Laminin subunit alpha (Laminin A chain) Drosophila melanogaster (Fruit fly) animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; basement membrane organization [GO:0071711]; cell adhesion mediated by integrin [GO:0033627]; dorsal trunk growth, open tracheal system [GO:0035001]; heart development [GO:0007507]; melanotic encapsulation of foreign target [GO:0035011]; mesoderm development [GO:0007498]; negative regulation of synaptic assembly at neuromuscular junction [GO:0045886]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888] GO:0005102; GO:0005576; GO:0005604; GO:0007411; GO:0007498; GO:0007507; GO:0008021; GO:0009887; GO:0009888; GO:0030155; GO:0030334; GO:0030424; GO:0033627; GO:0034446; GO:0035001; GO:0035011; GO:0036062; GO:0045886; GO:0045995; GO:0062023; GO:0071711 1728 XM_044326578.1 2096 1731 1342 2735 2397 Q00174 1.28e-34 Laminin subunit alpha (Laminin A chain) Drosophila melanogaster (Fruit fly) animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; basement membrane organization [GO:0071711]; cell adhesion mediated by integrin [GO:0033627]; dorsal trunk growth, open tracheal system [GO:0035001]; heart development [GO:0007507]; melanotic encapsulation of foreign target [GO:0035011]; mesoderm development [GO:0007498]; negative regulation of synaptic assembly at neuromuscular junction [GO:0045886]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888] GO:0005102; GO:0005576; GO:0005604; GO:0007411; GO:0007498; GO:0007507; GO:0008021; GO:0009887; GO:0009888; GO:0030155; GO:0030334; GO:0030424; GO:0033627; GO:0034446; GO:0035001; GO:0035011; GO:0036062; GO:0045886; GO:0045995; GO:0062023; GO:0071711 1729 XM_044326578.1 2096 1731 1342 2735 2397 Q00174 1.18e-32 Laminin subunit alpha (Laminin A chain) Drosophila melanogaster (Fruit fly) animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; basement membrane organization [GO:0071711]; cell adhesion mediated by integrin [GO:0033627]; dorsal trunk growth, open tracheal system [GO:0035001]; heart development [GO:0007507]; melanotic encapsulation of foreign target [GO:0035011]; mesoderm development [GO:0007498]; negative regulation of synaptic assembly at neuromuscular junction [GO:0045886]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888] GO:0005102; GO:0005576; GO:0005604; GO:0007411; GO:0007498; GO:0007507; GO:0008021; GO:0009887; GO:0009888; GO:0030155; GO:0030334; GO:0030424; GO:0033627; GO:0034446; GO:0035001; GO:0035011; GO:0036062; GO:0045886; GO:0045995; GO:0062023; GO:0071711 1730 XM_044326578.1 2096 1731 1342 2735 2397 Q00174 3.04e-31 Laminin subunit alpha (Laminin A chain) Drosophila melanogaster (Fruit fly) animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; basement membrane organization [GO:0071711]; cell adhesion mediated by integrin [GO:0033627]; dorsal trunk growth, open tracheal system [GO:0035001]; heart development [GO:0007507]; melanotic encapsulation of foreign target [GO:0035011]; mesoderm development [GO:0007498]; negative regulation of synaptic assembly at neuromuscular junction [GO:0045886]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888] GO:0005102; GO:0005576; GO:0005604; GO:0007411; GO:0007498; GO:0007507; GO:0008021; GO:0009887; GO:0009888; GO:0030155; GO:0030334; GO:0030424; GO:0033627; GO:0034446; GO:0035001; GO:0035011; GO:0036062; GO:0045886; GO:0045995; GO:0062023; GO:0071711 1731 XM_044326578.1 2096 1731 1342 2735 2397 Q00174 1.62e-28 Laminin subunit alpha (Laminin A chain) Drosophila melanogaster (Fruit fly) animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; basement membrane organization [GO:0071711]; cell adhesion mediated by integrin [GO:0033627]; dorsal trunk growth, open tracheal system [GO:0035001]; heart development [GO:0007507]; melanotic encapsulation of foreign target [GO:0035011]; mesoderm development [GO:0007498]; negative regulation of synaptic assembly at neuromuscular junction [GO:0045886]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888] GO:0005102; GO:0005576; GO:0005604; GO:0007411; GO:0007498; GO:0007507; GO:0008021; GO:0009887; GO:0009888; GO:0030155; GO:0030334; GO:0030424; GO:0033627; GO:0034446; GO:0035001; GO:0035011; GO:0036062; GO:0045886; GO:0045995; GO:0062023; GO:0071711 1732 XM_044326578.1 2096 1731 1342 2735 2397 Q00174 6.91e-26 Laminin subunit alpha (Laminin A chain) Drosophila melanogaster (Fruit fly) animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; basement membrane organization [GO:0071711]; cell adhesion mediated by integrin [GO:0033627]; dorsal trunk growth, open tracheal system [GO:0035001]; heart development [GO:0007507]; melanotic encapsulation of foreign target [GO:0035011]; mesoderm development [GO:0007498]; negative regulation of synaptic assembly at neuromuscular junction [GO:0045886]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888] GO:0005102; GO:0005576; GO:0005604; GO:0007411; GO:0007498; GO:0007507; GO:0008021; GO:0009887; GO:0009888; GO:0030155; GO:0030334; GO:0030424; GO:0033627; GO:0034446; GO:0035001; GO:0035011; GO:0036062; GO:0045886; GO:0045995; GO:0062023; GO:0071711 1733 XM_044326578.1 2096 1731 1342 2735 2397 Q00174 1.33e-23 Laminin subunit alpha (Laminin A chain) Drosophila melanogaster (Fruit fly) animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; basement membrane organization [GO:0071711]; cell adhesion mediated by integrin [GO:0033627]; dorsal trunk growth, open tracheal system [GO:0035001]; heart development [GO:0007507]; melanotic encapsulation of foreign target [GO:0035011]; mesoderm development [GO:0007498]; negative regulation of synaptic assembly at neuromuscular junction [GO:0045886]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888] GO:0005102; GO:0005576; GO:0005604; GO:0007411; GO:0007498; GO:0007507; GO:0008021; GO:0009887; GO:0009888; GO:0030155; GO:0030334; GO:0030424; GO:0033627; GO:0034446; GO:0035001; GO:0035011; GO:0036062; GO:0045886; GO:0045995; GO:0062023; GO:0071711 1734 XM_044326578.1 2096 1731 1342 2735 2397 Q00174 2.66e-23 Laminin subunit alpha (Laminin A chain) Drosophila melanogaster (Fruit fly) animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; basement membrane organization [GO:0071711]; cell adhesion mediated by integrin [GO:0033627]; dorsal trunk growth, open tracheal system [GO:0035001]; heart development [GO:0007507]; melanotic encapsulation of foreign target [GO:0035011]; mesoderm development [GO:0007498]; negative regulation of synaptic assembly at neuromuscular junction [GO:0045886]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888] GO:0005102; GO:0005576; GO:0005604; GO:0007411; GO:0007498; GO:0007507; GO:0008021; GO:0009887; GO:0009888; GO:0030155; GO:0030334; GO:0030424; GO:0033627; GO:0034446; GO:0035001; GO:0035011; GO:0036062; GO:0045886; GO:0045995; GO:0062023; GO:0071711 1735 XM_044320843.1 21 107 6 0 9 Q8K3Z0 7.96e-29 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 1736 XM_029339176.2 69 33 58 107 247 Q8BMZ5 9.12e-26 tRNA-splicing endonuclease subunit Sen34 (EC 4.6.1.16) (Leukocyte receptor cluster member 5 homolog) (tRNA-intron endonuclease Sen34) Mus musculus (Mouse) mRNA processing [GO:0006397]; tRNA-type intron splice site recognition and cleavage [GO:0000379] GO:0000213; GO:0000214; GO:0000379; GO:0003676; GO:0005654; GO:0005730; GO:0006397; GO:0016829 1737 XM_044311821.1 230 379 148 168 422 Q9VBW3 1.67e-57 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 1738 XM_029329144.2 268 0 42 312 300 Q12802 1.31e-81 A-kinase anchor protein 13 (AKAP-13) (AKAP-Lbc) (Breast cancer nuclear receptor-binding auxiliary protein) (Guanine nucleotide exchange factor Lbc) (Human thyroid-anchoring protein 31) (Lymphoid blast crisis oncogene) (LBC oncogene) (Non-oncogenic Rho GTPase-specific GTP exchange factor) (Protein kinase A-anchoring protein 13) (PRKA13) (p47) Homo sapiens (Human) adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process [GO:0086023]; adrenergic receptor signaling pathway [GO:0071875]; bone development [GO:0060348]; cardiac muscle cell differentiation [GO:0055007]; cell growth involved in cardiac muscle cell development [GO:0061049]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; nuclear export [GO:0051168]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Rho protein signal transduction [GO:0035025]; regulation of Rho protein signal transduction [GO:0035023]; regulation of sarcomere organization [GO:0060297]; regulation of small GTPase mediated signal transduction [GO:0051056] GO:0005078; GO:0005085; GO:0005634; GO:0005829; GO:0005938; GO:0007186; GO:0007507; GO:0016020; GO:0031267; GO:0035023; GO:0035025; GO:0043123; GO:0043406; GO:0046872; GO:0048471; GO:0051018; GO:0051056; GO:0051168; GO:0055007; GO:0060090; GO:0060297; GO:0060348; GO:0061049; GO:0071875; GO:0086023 1739 XR_006393933.1 15278 23262 189643 22554 30771 NA NA NA NA NA NA 1740 XM_044324822.1 0 0 0 20 0 Q16281 0 Cyclic nucleotide-gated cation channel alpha-3 (Cone photoreceptor cGMP-gated channel subunit alpha) (Cyclic nucleotide-gated channel alpha-3) (CNG channel alpha-3) (CNG-3) (CNG3) Homo sapiens (Human) cation transmembrane transport [GO:0098655]; cation transport [GO:0006812]; inorganic cation import across plasma membrane [GO:0098659]; response to cAMP [GO:0051591]; response to corticosteroid [GO:0031960]; response to magnesium ion [GO:0032026]; signal transduction [GO:0007165]; visual perception [GO:0007601] GO:0005222; GO:0005223; GO:0005737; GO:0005886; GO:0006812; GO:0007165; GO:0007601; GO:0008022; GO:0015276; GO:0017071; GO:0030425; GO:0030553; GO:0031960; GO:0032026; GO:0043194; GO:0043204; GO:0044877; GO:0051591; GO:0097386; GO:0098655; GO:0098659; GO:1902495 1741 XR_006393166.1 9 18 54 8 91 NA NA NA NA NA NA 1742 XM_029352084.2 916 538 629 756 729 Q8HZY8 6.38e-68 Coiled-coil domain-containing protein 148 Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA NA 1743 XM_029340676.2 36 93 87 77 38 NA NA NA NA NA NA 1744 XM_044307078.1 81 8 0 14 15 Q9BUD6 6.04e-32 Spondin-2 (Differentially expressed in cancerous and non-cancerous lung cells 1) (DIL-1) (Mindin) Homo sapiens (Human) cell adhesion [GO:0007155]; cellular response to lipopolysaccharide [GO:0071222]; defense response to fungus [GO:0050832]; defense response to virus [GO:0051607]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; mast cell mediated immunity [GO:0002448]; opsonization [GO:0008228]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of tumor necrosis factor production [GO:0032760] GO:0001530; GO:0002448; GO:0003823; GO:0007155; GO:0008228; GO:0031012; GO:0032755; GO:0032760; GO:0043152; GO:0045087; GO:0046872; GO:0050832; GO:0051607; GO:0060907; GO:0070062; GO:0071222 1745 XM_044307078.1 81 8 0 14 15 Q9BUD6 4.96e-22 Spondin-2 (Differentially expressed in cancerous and non-cancerous lung cells 1) (DIL-1) (Mindin) Homo sapiens (Human) cell adhesion [GO:0007155]; cellular response to lipopolysaccharide [GO:0071222]; defense response to fungus [GO:0050832]; defense response to virus [GO:0051607]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; mast cell mediated immunity [GO:0002448]; opsonization [GO:0008228]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of tumor necrosis factor production [GO:0032760] GO:0001530; GO:0002448; GO:0003823; GO:0007155; GO:0008228; GO:0031012; GO:0032755; GO:0032760; GO:0043152; GO:0045087; GO:0046872; GO:0050832; GO:0051607; GO:0060907; GO:0070062; GO:0071222 1746 XR_006397890.1 8 0 0 0 0 NA NA NA NA NA NA 1747 XM_044312409.1 30 0 0 0 0 P35067 9.33e-85 Histone H2B Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 1748 XM_029339905.2 272 242 89 178 60 Q98925 2.65e-35 Interferon regulatory factor 2 (IRF-2) Gallus gallus (Chicken) immune system process [GO:0002376]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0002376; GO:0005634; GO:0006357 1749 XM_044315789.1 8 4 19 14 96 NA NA NA NA NA NA 1750 XR_006394224.1 45 44 2 6 85 NA NA NA NA NA NA 1751 XM_029344767.2 0 0 111 0 0 P35668 3.15e-119 Glutathione synthetase (GSH synthetase) (GSH-S) (EC 6.3.2.3) (Glutathione synthase) Xenopus laevis (African clawed frog) NA GO:0000287; GO:0004363; GO:0005524; GO:0042803; GO:0043295 1752 XM_044310981.1 53 8 6 43 74 NA NA NA NA NA NA 1753 XM_029336640.2 3383 1778 713 3256 832 O88576 0 Sodium-dependent neutral amino acid transporter B(0)AT3 (Sodium- and chloride-dependent transporter XTRP2) (Solute carrier family 6 member 18) (System B(0) neutral amino acid transporter AT3) Mus musculus (Mouse) amino acid transmembrane transport [GO:0003333]; neurotransmitter transport [GO:0006836]; neutral amino acid transport [GO:0015804]; renal amino acid absorption [GO:1990297]; sodium ion transmembrane transport [GO:0035725] GO:0003333; GO:0005886; GO:0006836; GO:0015175; GO:0015804; GO:0016324; GO:0031526; GO:0035725; GO:0140931; GO:1990297 1754 XM_044319594.1 5 1 0 18 0 P04323 2.38e-57 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 1755 XR_006396446.1 3 0 0 0 11 NA NA NA NA NA NA 1756 XM_044316750.1 11 0 1 20 8 NA NA NA NA NA NA 1757 XR_003824873.2 29 4 17 40 35 NA NA NA NA NA NA 1758 XM_044319955.1 34 169 197 242 183 Q6PC60 1.21e-59 Histone H2B 3 Danio rerio (Zebrafish) (Brachydanio rerio) nucleosome assembly [GO:0006334] GO:0000785; GO:0000786; GO:0003677; GO:0005634; GO:0006334; GO:0030527; GO:0046982 1759 XM_044312012.1 2 20 10 24 11 Q95LR0 5.23e-60 Cilia- and flagella-associated protein 91 (CFAP91) (AMY-1-associating protein expressed in testis 1) (AAT-1) (MYCBP/AMY-1-associated testis-expressed protein 1) (Protein MAATS1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) axonemal central apparatus assembly [GO:1904158]; cell differentiation [GO:0030154]; cilium movement [GO:0003341]; spermatogenesis [GO:0007283] GO:0003341; GO:0005739; GO:0005930; GO:0007283; GO:0030154; GO:0031514; GO:1904158 1760 XM_044312012.1 2 20 10 24 11 Q95LR0 5.23e-60 Cilia- and flagella-associated protein 91 (CFAP91) (AMY-1-associating protein expressed in testis 1) (AAT-1) (MYCBP/AMY-1-associated testis-expressed protein 1) (Protein MAATS1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) axonemal central apparatus assembly [GO:1904158]; cell differentiation [GO:0030154]; cilium movement [GO:0003341]; spermatogenesis [GO:0007283] GO:0003341; GO:0005739; GO:0005930; GO:0007283; GO:0030154; GO:0031514; GO:1904158 1761 XR_006398041.1 11 68 0 584 69 Q0P5X1 1.51e-56 Leucine-rich repeat and IQ domain-containing protein 1 Mus musculus (Mouse) NA GO:0005737; GO:0019901 1762 XM_029330985.2 2046 1377 835 1806 1367 Q9WU81 7.67e-158 Glucose-6-phosphate exchanger SLC37A2 (Solute carrier family 37 member 2) (cAMP-inducible protein 2) Mus musculus (Mouse) carbohydrate transport [GO:0008643]; glucose-6-phosphate transport [GO:0015760]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerol-3-phosphate transmembrane transport [GO:0015794]; glycerophosphate shuttle [GO:0006127]; phosphate ion transmembrane transport [GO:0035435] GO:0005789; GO:0006072; GO:0006127; GO:0008643; GO:0015169; GO:0015760; GO:0015794; GO:0035435; GO:0061513 1763 XM_029347239.2 161 117 69 82 196 NA NA NA NA NA NA 1764 XM_044314827.1 0 4 1 3 20 NA NA NA NA NA NA 1765 XR_006391965.1 0 0 0 0 16 NA NA NA NA NA NA 1766 XR_006391362.1 0 0 5 0 87 NA NA NA NA NA NA 1767 XM_044315651.1 5 31 16 18 4 NA NA NA NA NA NA 1768 XM_044324197.1 559 330 366 469 609 Q9H1I8 7.74e-154 Activating signal cointegrator 1 complex subunit 2 (ASC-1 complex subunit p100) (Trip4 complex subunit p100) Homo sapiens (Human) DNA dealkylation involved in DNA repair [GO:0006307]; DNA duplex unwinding [GO:0032508]; regulation of DNA-templated transcription [GO:0006355]; rescue of stalled ribosome [GO:0072344]; ribosome disassembly [GO:0032790]; ribosome-associated ubiquitin-dependent protein catabolic process [GO:1990116] GO:0005634; GO:0005654; GO:0006307; GO:0006355; GO:0016607; GO:0032508; GO:0032790; GO:0043130; GO:0072344; GO:0099053; GO:1990116; GO:1990391 1769 XM_029355549.2 1142 472 616 994 1020 A4IIW7 7.08e-147 Cyclin-dependent kinase 14 (EC 2.7.11.22) (Cell division protein kinase 14) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell division [GO:0051301]; G2/M transition of mitotic cell cycle [GO:0000086]; protein phosphorylation [GO:0006468]; regulation of canonical Wnt signaling pathway [GO:0060828]; Wnt signaling pathway [GO:0016055] GO:0000086; GO:0000308; GO:0004693; GO:0005524; GO:0005886; GO:0006468; GO:0016055; GO:0051301; GO:0060828; GO:0106310 1770 XM_044322621.1 0 0 0 0 23 NA NA NA NA NA NA 1771 XM_029326987.2 600 96 261 89 317 NA NA NA NA NA NA 1772 XM_029324912.2 1 1 3 0 78 NA NA NA NA NA NA 1773 XM_044315050.1 2 7 0 40 0 NA NA NA NA NA NA 1774 XM_029353639.2 8 34 18 2 19 NA NA NA NA NA NA 1775 XM_044320255.1 4516 4320 1565 1681 2899 NA NA NA NA NA NA 1776 XM_044323545.1 4 0 23 9 25 NA NA NA NA NA NA 1777 XM_029336144.2 2477 3698 2884 1630 2930 Q99068 3.89e-33 Alpha-2-macroglobulin receptor-associated protein (Alpha-2-MRAP) (Gp330-binding 45 kDa protein) (Low density lipoprotein receptor-related protein-associated protein 1) (RAP) Rattus norvegicus (Rat) amyloid-beta clearance by transcytosis [GO:0150093]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of cell death [GO:0060548]; negative regulation of protein binding [GO:0032091]; negative regulation of receptor internalization [GO:0002091]; negative regulation of very-low-density lipoprotein particle clearance [GO:0010916]; regulation of receptor-mediated endocytosis [GO:0048259]; signal transduction [GO:0007165] GO:0002091; GO:0005737; GO:0005768; GO:0005791; GO:0005793; GO:0005794; GO:0005796; GO:0005801; GO:0005886; GO:0007165; GO:0008201; GO:0009986; GO:0010916; GO:0012505; GO:0031904; GO:0031982; GO:0032091; GO:0035473; GO:0048018; GO:0048019; GO:0048237; GO:0048259; GO:0050750; GO:0060548; GO:0070326; GO:0150093; GO:1900222 1778 XM_029352110.2 46 12 33 10 81 P13608 2.06e-21 Aggrecan core protein (Cartilage-specific proteoglycan core protein) (CSPCP) Bos taurus (Bovine) cell adhesion [GO:0007155]; central nervous system development [GO:0007417]; skeletal system development [GO:0001501] GO:0001501; GO:0005509; GO:0005540; GO:0005576; GO:0007155; GO:0007417; GO:0030246; GO:0031012 1779 XM_029354558.2 549 620 496 547 548 Q6DBQ8 5.46e-39 Ceramide-1-phosphate transfer protein (Glycolipid transfer protein domain-containing protein 1) (CPTP) Danio rerio (Zebrafish) (Brachydanio rerio) ceramide 1-phosphate transport [GO:1902389]; ceramide transport [GO:0035627]; intermembrane lipid transfer [GO:0120009]; negative regulation of autophagy [GO:0010507]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226] GO:0005543; GO:0005640; GO:0005794; GO:0005829; GO:0005886; GO:0010008; GO:0010507; GO:0032691; GO:0035627; GO:0120009; GO:1900226; GO:1902387; GO:1902388; GO:1902389 1780 XR_006391527.1 0 1 0 8 0 NA NA NA NA NA NA 1781 XM_044309707.1 28 151 13 24 36 Q8NB78 4.36e-128 Lysine-specific histone demethylase 2 (EC 1.14.99.66) (Flavin-containing amine oxidase domain-containing protein 1) (Lysine-specific histone demethylase 1B) Homo sapiens (Human) DNA methylation involved in gamete generation [GO:0043046]; histone H3-K4 demethylation [GO:0034720]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA methylation [GO:0044030]; regulation of gene expression by genomic imprinting [GO:0006349] GO:0000122; GO:0000786; GO:0003682; GO:0005634; GO:0005654; GO:0006349; GO:0008270; GO:0016491; GO:0032452; GO:0034720; GO:0042393; GO:0043046; GO:0044030; GO:0045944; GO:0050660; GO:0071949; GO:0140682 1782 XM_029331218.2 149 85 28 129 42 Q4KM64 1.88e-27 Protein jagunal homolog 1 Rattus norvegicus (Rat) cellular response to organic substance [GO:0071310]; defense response to fungus [GO:0050832]; endoplasmic reticulum organization [GO:0007029]; granulocyte colony-stimulating factor signaling pathway [GO:0038158]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; neutrophil differentiation [GO:0030223]; neutrophil mediated immunity [GO:0002446]; neutrophil migration [GO:1990266]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] GO:0002446; GO:0005783; GO:0005789; GO:0007029; GO:0015031; GO:0016192; GO:0030223; GO:0038158; GO:0050832; GO:0061179; GO:0071310; GO:1990266 1783 XM_044310477.1 19 28 26 29 35 NA NA NA NA NA NA 1784 XM_044327595.1 307 67 95 120 48 Q6TMK4 5.08e-90 Peroxinectin A (EC 1.11.1.7) Dictyostelium discoideum (Social amoeba) defense response to bacterium [GO:0042742]; hydrogen peroxide catabolic process [GO:0042744]; immune response [GO:0006955]; response to oxidative stress [GO:0006979] GO:0004447; GO:0004601; GO:0005576; GO:0005783; GO:0006955; GO:0006979; GO:0020037; GO:0036393; GO:0042742; GO:0042744; GO:0140825 1785 XM_044327460.1 1 0 6 4 0 NA NA NA NA NA NA 1786 XM_044329015.1 439 182 114 249 276 NA NA NA NA NA NA 1787 XM_029332986.2 4300 4143 2389 3975 4217 P63086 0 Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2) Rattus norvegicus (Rat) aging [GO:0007568]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; B cell receptor signaling pathway [GO:0050853]; Bergmann glial cell differentiation [GO:0060020]; cardiac neural crest cell development involved in heart development [GO:0061308]; caveolin-mediated endocytosis [GO:0072584]; cell cycle [GO:0007049]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid starvation [GO:0034198]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to dopamine [GO:1903351]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to organic substance [GO:0071310]; cellular response to reactive oxygen species [GO:0034614]; cellular response to tumor necrosis factor [GO:0071356]; cytosine metabolic process [GO:0019858]; decidualization [GO:0046697]; diadenosine tetraphosphate biosynthetic process [GO:0015966]; ERBB signaling pathway [GO:0038127]; ERK1 and ERK2 cascade [GO:0070371]; face development [GO:0060324]; heart development [GO:0007507]; insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009]; intracellular signal transduction [GO:0035556]; labyrinthine layer blood vessel development [GO:0060716]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; long-term synaptic potentiation [GO:0060291]; lung morphogenesis [GO:0060425]; mammary gland epithelial cell proliferation [GO:0033598]; MAPK cascade [GO:0000165]; negative regulation of cell differentiation [GO:0045596]; neural crest cell development [GO:0014032]; outer ear morphogenesis [GO:0042473]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of macrophage proliferation [GO:0120041]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; positive regulation of translation [GO:0045727]; protein phosphorylation [GO:0006468]; regulation of cellular pH [GO:0030641]; regulation of cytoskeleton organization [GO:0051493]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of Golgi inheritance [GO:0090170]; regulation of ossification [GO:0030278]; regulation of protein stability [GO:0031647]; regulation of stress-activated MAPK cascade [GO:0032872]; response to epidermal growth factor [GO:0070849]; response to estrogen [GO:0043627]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to toxic substance [GO:0009636]; sensory perception of pain [GO:0019233]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; trachea formation [GO:0060440] GO:0000165; GO:0001784; GO:0003690; GO:0004672; GO:0004674; GO:0004707; GO:0004708; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005769; GO:0005770; GO:0005794; GO:0005815; GO:0005829; GO:0005856; GO:0005886; GO:0005901; GO:0005925; GO:0006468; GO:0006915; GO:0006974; GO:0007049; GO:0007165; GO:0007166; GO:0007507; GO:0007568; GO:0008284; GO:0008286; GO:0008353; GO:0009636; GO:0009887; GO:0010628; GO:0010759; GO:0010800; GO:0014032; GO:0014069; GO:0015966; GO:0016301; GO:0018105; GO:0018107; GO:0019233; GO:0019858; GO:0019901; GO:0019902; GO:0030278; GO:0030335; GO:0030424; GO:0030641; GO:0030878; GO:0031143; GO:0031435; GO:0031647; GO:0031663; GO:0032212; GO:0032496; GO:0032839; GO:0032872; GO:0032991; GO:0033598; GO:0034198; GO:0034614; GO:0035094; GO:0035556; GO:0038127; GO:0042307; GO:0042473; GO:0042802; GO:0043204; GO:0043330; GO:0043627; GO:0045596; GO:0045727; GO:0045893; GO:0046697; GO:0048009; GO:0048538; GO:0050852; GO:0050853; GO:0051403; GO:0051493; GO:0051973; GO:0060020; GO:0060045; GO:0060291; GO:0060324; GO:0060425; GO:0060440; GO:0060716; GO:0061308; GO:0070371; GO:0070849; GO:0071276; GO:0071310; GO:0071356; GO:0072584; GO:0072686; GO:0090170; GO:0097011; GO:0106310; GO:0120041; GO:1903351; GO:1904355; GO:2000641 1788 XM_029335128.2 35 11 18 8 54 P49288 2.91e-27 Melatonin receptor type 1C (Mel-1C-R) (Mel1c receptor) (CKB) Gallus gallus (Chicken) G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of glucose import [GO:0046325]; negative regulation of glycolytic process [GO:0045820] GO:0004930; GO:0005654; GO:0005886; GO:0007186; GO:0008502; GO:0045820; GO:0046325; GO:1904408 1789 XM_029348784.2 258 153 279 275 681 Q9BZ29 0 Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin-1) (Zizimin-1) Homo sapiens (Human) positive regulation of GTPase activity [GO:0043547]; small GTPase mediated signal transduction [GO:0007264] GO:0005085; GO:0005829; GO:0007264; GO:0012505; GO:0016020; GO:0043547; GO:0045296 1790 XM_044310937.1 2 0 8 11 201 NA NA NA NA NA NA 1791 XM_044317195.1 1540 93 429 413 73 F2Z5G5 4.76e-94 Alpha-centractin (Centractin) (ARP1) Sus scrofa (Pig) NA NA 1792 XM_044326782.1 12 11 41 4 0 NA NA NA NA NA NA 1793 XM_044314376.1 9 9 25 25 116 P35546 3.04e-78 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; anatomical structure morphogenesis [GO:0009653]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006919; GO:0007156; GO:0007158; GO:0007169; GO:0007399; GO:0009410; GO:0009653; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030182; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0098797; GO:2001241 1794 XM_044315522.1 0 0 0 41 73 NA NA NA NA NA NA 1795 XM_029343459.2 90 44 0 0 0 NA NA NA NA NA NA 1796 XM_029328468.2 209 96 29 166 118 NA NA NA NA NA NA 1797 XM_029336526.2 4 2 0 1 15 NA NA NA NA NA NA 1798 XM_029347893.2 272 111 60 184 260 NA NA NA NA NA NA 1799 XM_044310433.1 27 5 8 6 1 NA NA NA NA NA NA 1800 XM_044328881.1 34 37 70 122 80 Q7TN88 2.01e-65 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 1801 XM_044328881.1 34 37 70 122 80 Q7TN88 5.11e-54 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 1802 XR_006398170.1 186 101 124 14 10 NA NA NA NA NA NA 1803 XM_029353489.2 2627 2207 1593 2675 3137 Q5ZID6 2.48e-60 Cytosolic 5'-nucleotidase 3A (EC 3.1.3.5) (7-methylguanosine phosphate-specific 5'-nucleotidase) (7-methylguanosine nucleotidase) (EC 3.1.3.91) (Cytosolic 5'-nucleotidase 3) (Cytosolic 5'-nucleotidase III) (cN-III) (Pyrimidine 5'-nucleotidase 1) (P5'N-1) (P5N-1) (PN-I) Gallus gallus (Chicken) CMP catabolic process [GO:0006248] GO:0000166; GO:0000287; GO:0005737; GO:0005783; GO:0005829; GO:0006248; GO:0008253; GO:0016604; GO:0016740; GO:0106411 1804 XM_044311511.1 151 29 60 116 275 NA NA NA NA NA NA 1805 XM_044312205.1 25 8 19 18 38 NA NA NA NA NA NA 1806 XM_044324853.1 165 198 200 209 209 Q969H0 0 F-box/WD repeat-containing protein 7 (Archipelago homolog) (hAgo) (F-box and WD-40 domain-containing protein 7) (F-box protein FBX30) (SEL-10) (hCdc4) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; DNA repair [GO:0006281]; lipid homeostasis [GO:0055088]; lung development [GO:0030324]; negative regulation of gene expression [GO:0010629]; negative regulation of hepatocyte proliferation [GO:2000346]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of osteoclast development [GO:2001205]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; negative regulation of SREBP signaling pathway [GO:2000639]; negative regulation of triglyceride biosynthetic process [GO:0010868]; Notch signaling pathway [GO:0007219]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903378]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein destabilization [GO:0031648]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of cell cycle G1/S phase transition [GO:1902806]; regulation of cell migration involved in sprouting angiogenesis [GO:0090049]; regulation of circadian rhythm [GO:0042752]; regulation of lipid storage [GO:0010883]; regulation of protein localization [GO:0032880]; rhythmic process [GO:0048511]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; sister chromatid cohesion [GO:0007062]; ubiquitin recycling [GO:0010992]; vasculature development [GO:0001944]; vasculogenesis [GO:0001570] GO:0001570; GO:0001944; GO:0005634; GO:0005654; GO:0005694; GO:0005730; GO:0005737; GO:0005739; GO:0005783; GO:0005794; GO:0005829; GO:0006281; GO:0006974; GO:0007062; GO:0007219; GO:0010629; GO:0010868; GO:0010883; GO:0010992; GO:0016567; GO:0019005; GO:0030324; GO:0030332; GO:0030674; GO:0031146; GO:0031398; GO:0031625; GO:0031648; GO:0032880; GO:0032991; GO:0034644; GO:0042752; GO:0042802; GO:0043130; GO:0043161; GO:0045741; GO:0045746; GO:0048471; GO:0048511; GO:0050816; GO:0050821; GO:0051443; GO:0055088; GO:0070374; GO:0090049; GO:0097027; GO:1901800; GO:1902806; GO:1903026; GO:1903146; GO:1903378; GO:1903955; GO:1990452; GO:2000060; GO:2000346; GO:2000639; GO:2001205 1807 XM_029352603.2 20 10 5 38 42 NA NA NA NA NA NA 1808 XM_044314377.1 6 1 3 0 16 NA NA NA NA NA NA 1809 XM_044308592.1 880 546 577 781 1323 O75694 0 Nuclear pore complex protein Nup155 (155 kDa nucleoporin) (Nucleoporin Nup155) Homo sapiens (Human) atrial cardiac muscle cell action potential [GO:0086014]; miRNA processing [GO:0035196]; mRNA export from nucleus [GO:0006406]; nuclear envelope organization [GO:0006998]; nucleocytoplasmic transport [GO:0006913]; protein import into nucleus [GO:0006606]; protein localization to nuclear inner membrane [GO:0036228]; RNA export from nucleus [GO:0006405]; transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000972] GO:0000972; GO:0005635; GO:0005643; GO:0005829; GO:0006405; GO:0006406; GO:0006606; GO:0006913; GO:0006998; GO:0016020; GO:0017056; GO:0031965; GO:0035196; GO:0036228; GO:0044611; GO:0086014 1810 XM_029339015.2 71 5 12 2 3 Q6MHJ5 2.63e-26 ATP-dependent DNA helicase pif1 (EC 3.6.4.12) Bdellovibrio bacteriovorus (strain ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100) DNA recombination [GO:0006310]; DNA repair [GO:0006281]; telomere maintenance [GO:0000723] GO:0000723; GO:0003677; GO:0003678; GO:0005524; GO:0006281; GO:0006310; GO:0016887 1811 XM_029332318.2 167 195 117 109 128 F7B645 2.1e-90 Transmembrane protein 231 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cilium assembly [GO:0060271]; smoothened signaling pathway [GO:0007224] GO:0007224; GO:0035869; GO:0036038; GO:0060170; GO:0060271 1812 XR_006395633.1 0 0 0 59 10 G5EBX9 4.39e-179 Serine/threonine-protein phosphatase with EF-hands pef-1 (CePPEF) (EC 3.1.3.16) (Phosphatase with EF hands 1) Caenorhabditis elegans detection of stimulus involved in sensory perception [GO:0050906] GO:0004722; GO:0005506; GO:0005509; GO:0005634; GO:0005829; GO:0005886; GO:0005929; GO:0017018; GO:0030145; GO:0030424; GO:0030425; GO:0043025; GO:0043204; GO:0050906 1813 XM_029329865.2 330 17 108 605 186 P20072 1.37e-70 Annexin A7 (Annexin VII) (Annexin-7) (Synexin) Bos taurus (Bovine) NA GO:0005509; GO:0005544; GO:0005634; GO:0005737; GO:0042584 1814 XM_029332050.2 732 209 508 725 523 NA NA NA NA NA NA 1815 XM_044325531.1 133 87 33 0 0 B1AS29 1.56e-82 Glutamate receptor ionotropic, kainate 3 (GluK3) (Glutamate receptor 7) (GluR-7) (GluR7) Mus musculus (Mouse) G protein-coupled glutamate receptor signaling pathway [GO:0007216]; glutamate receptor signaling pathway [GO:0007215]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; regulation of membrane potential [GO:0042391]; synaptic transmission, glutamatergic [GO:0035249] GO:0001640; GO:0004970; GO:0005886; GO:0007215; GO:0007216; GO:0008066; GO:0015276; GO:0015277; GO:0030424; GO:0030425; GO:0032839; GO:0032983; GO:0035249; GO:0038023; GO:0042391; GO:0042734; GO:0043195; GO:0043204; GO:0045211; GO:0050804; GO:0051967; GO:0098978; GO:0099507; GO:1904315 1816 XR_003825216.2 22 80 11 127 132 NA NA NA NA NA NA 1817 XM_044326289.1 16 8 1 20 18 Q5VU97 2.15e-147 VWFA and cache domain-containing protein 1 (Cache domain-containing protein 1) Homo sapiens (Human) NA GO:0005245; GO:0005891 1818 XM_029357671.2 135 149 239 194 244 NA NA NA NA NA NA 1819 XM_029355732.2 1065 918 414 800 916 Q5RF04 5.83e-70 Probable ribosome biogenesis protein RLP24 (Ribosomal L24 domain-containing protein 1) (Ribosomal protein L24-like) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) ribosome biogenesis [GO:0042254] GO:0005654; GO:0005730; GO:0042254 1820 XM_029354240.2 0 0 10 12 17 NA NA NA NA NA NA 1821 XR_006393609.1 21 0 0 2 13 NA NA NA NA NA NA 1822 XM_029323523.2 5797 2679 4571 7573 5770 Q8IVF7 5.68e-64 Formin-like protein 3 (Formin homology 2 domain-containing protein 3) (WW domain-binding protein 3) (WBP-3) Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; angiogenesis [GO:0001525]; cell migration [GO:0016477]; cortical actin cytoskeleton organization [GO:0030866]; cytoskeleton organization [GO:0007010]; filopodium assembly [GO:0046847]; regulation of cell shape [GO:0008360] GO:0001525; GO:0005737; GO:0005794; GO:0005829; GO:0005886; GO:0007010; GO:0008360; GO:0016477; GO:0030866; GO:0031267; GO:0031532; GO:0032794; GO:0043231; GO:0046847; GO:0051015 1823 XM_029347629.2 992 1671 27 310 1029 NA NA NA NA NA NA 1824 XR_006395019.1 222 281 28 384 64 NA NA NA NA NA NA 1825 XM_029358549.2 0 0 6 0 15 NA NA NA NA NA NA 1826 XR_006396678.1 105 30 62 69 92 NA NA NA NA NA NA 1827 XM_044308063.1 1441 1415 621 1141 476 NA NA NA NA NA NA 1828 XM_044326549.1 61 129 93 49 195 NA NA NA NA NA NA 1829 XM_044316960.1 17 4 0 0 3 NA NA NA NA NA NA 1830 XM_044319667.1 0 0 0 1 6 P30974 1.01e-32 Tachykinin-like peptides receptor 86C (NKD) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; inter-male aggressive behavior [GO:0002121]; neuropeptide signaling pathway [GO:0007218]; tachykinin receptor signaling pathway [GO:0007217] GO:0002121; GO:0004995; GO:0005886; GO:0007186; GO:0007217; GO:0007218; GO:0008188; GO:0016020 1831 XM_029344730.2 1222 2436 991 938 987 NA NA NA NA NA NA 1832 XM_044307829.1 0 0 0 0 22 NA NA NA NA NA NA 1833 XR_006397260.1 1 32 0 7 19 NA NA NA NA NA NA 1834 XM_044328124.1 5244 3355 1900 5390 3896 C3YWU0 0 Alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucoside fucohydrolase) Branchiostoma floridae (Florida lancelet) (Amphioxus) fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139] GO:0004560; GO:0005576; GO:0005764; GO:0006004; GO:0016139 1835 XM_029327542.2 4 0 4 2 27 NA NA NA NA NA NA 1836 XM_029346468.2 2 21 24 14 17 NA NA NA NA NA NA 1837 XR_006394510.1 653 22 245 37 217 NA NA NA NA NA NA 1838 XM_044324543.1 0 22 0 6 0 NA NA NA NA NA NA 1839 XM_044316567.1 21 1 12 5 41 NA NA NA NA NA NA 1840 XM_029355943.2 598 816 513 487 520 Q5ZJW4 5.6e-97 Vesicle-trafficking protein SEC22b (SEC22 vesicle-trafficking protein homolog B) Gallus gallus (Chicken) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; negative regulation of autophagosome assembly [GO:1902902]; positive regulation of protein catabolic process [GO:0045732]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; vesicle fusion with Golgi apparatus [GO:0048280] GO:0000139; GO:0005484; GO:0005789; GO:0005793; GO:0006888; GO:0006890; GO:0012507; GO:0015031; GO:0031201; GO:0033116; GO:0042470; GO:0045732; GO:0048280; GO:1902902 1841 XR_003824328.2 27 8 35 16 0 NA NA NA NA NA NA 1842 XR_006394765.1 920 823 568 480 690 NA NA NA NA NA NA 1843 XM_044313326.1 171 217 190 302 299 NA NA NA NA NA NA 1844 XM_044312385.1 0 6 0 0 0 NA NA NA NA NA NA 1845 XM_029347177.2 263 389 100 277 524 NA NA NA NA NA NA 1846 XM_044307114.1 0 0 21 0 0 Q9U6Y6 1.96e-112 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 1847 XM_029330496.2 1728 1277 714 1431 1570 Q29503 3.04e-111 Ubiquitin-conjugating enzyme E2 R2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme R2) (Ubiquitin carrier protein R2) (Ubiquitin-conjugating enzyme E2-CDC34B) (Ubiquitin-protein ligase R2) Oryctolagus cuniculus (Rabbit) protein K48-linked ubiquitination [GO:0070936]; protein monoubiquitination [GO:0006513] GO:0004842; GO:0005524; GO:0006513; GO:0061631; GO:0070936 1848 XM_029330502.2 110 116 66 152 46 NA NA NA NA NA NA 1849 XM_029344836.2 123 19 0 0 0 Q9H3L0 3.85e-69 Cobalamin trafficking protein CblD (CblD) (Methylmalonic aciduria and homocystinuria type D protein, mitochondrial) Homo sapiens (Human) cobalamin metabolic process [GO:0009235] GO:0005737; GO:0005739; GO:0005829; GO:0009235 1850 XM_029330901.2 100 17 24 153 221 NA NA NA NA NA NA 1851 XM_029341635.2 31 35 17 27 53 A7S4N4 2.1e-68 Probable serine incorporator Nematostella vectensis (Starlet sea anemone) phospholipid biosynthetic process [GO:0008654] GO:0005789; GO:0008654; GO:0016020 1852 XM_029341635.2 31 35 17 27 53 A7S4N4 1.07e-31 Probable serine incorporator Nematostella vectensis (Starlet sea anemone) phospholipid biosynthetic process [GO:0008654] GO:0005789; GO:0008654; GO:0016020 1853 XR_003825862.2 49 56 76 63 36 NA NA NA NA NA NA 1854 XM_029344972.2 879 619 589 966 613 P70445 2e-30 Eukaryotic translation initiation factor 4E-binding protein 2 (4E-BP2) (eIF4E-binding protein 2) (Phosphorylated heat- and acid-stable protein regulated by insulin 2) (PHAS-II) Mus musculus (Mouse) insulin receptor signaling pathway [GO:0008286]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of translational initiation [GO:0045947]; regulation of synaptic plasticity [GO:0048167]; regulation of translational initiation [GO:0006446]; social behavior [GO:0035176]; TOR signaling [GO:0031929] GO:0005737; GO:0006446; GO:0007613; GO:0008190; GO:0008286; GO:0030371; GO:0031929; GO:0035176; GO:0045947; GO:0048167; GO:0050804; GO:0098794 1855 XM_044314419.1 35 63 14 73 41 NA NA NA NA NA NA 1856 XR_006396928.1 27 32 20 15 22 NA NA NA NA NA NA 1857 XM_044316682.1 28 12 73 161 0 NA NA NA NA NA NA 1858 XM_044313436.1 5 0 0 17 0 NA NA NA NA NA NA 1859 XM_044324295.1 2343 2304 1749 2895 2812 Q6DFR2 0 E3 ubiquitin-protein ligase CBL-B (EC 2.3.2.27) (RING-type E3 ubiquitin transferase CBL-B) (SH3-binding protein CBL-B) (Signal transduction protein CBL-B) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell surface receptor signaling pathway [GO:0007166]; regulation of platelet-derived growth factor receptor-alpha signaling pathway [GO:2000583] GO:0001784; GO:0004842; GO:0005509; GO:0005737; GO:0007166; GO:2000583 1860 XM_029352174.2 17 3 4 4 21 NA NA NA NA NA NA 1861 XM_044326683.1 67 60 0 129 77 Q05B79 0 ATP-dependent DNA/RNA helicase DHX36 (EC 3.6.4.12) (EC 3.6.4.13) (DEAD/H box polypeptide 36) (DEAH-box protein 36) (G4-resolvase-1) (G4R1) (MLE-like protein 1) (RNA helicase associated with AU-rich element protein) Bos taurus (Bovine) 3'-UTR-mediated mRNA destabilization [GO:0061158]; cell differentiation [GO:0030154]; cellular response to arsenite ion [GO:1903843]; cellular response to heat [GO:0034605]; cellular response to UV [GO:0034644]; defense response to virus [GO:0051607]; G-quadruplex DNA unwinding [GO:0044806]; innate immune response [GO:0045087]; negative regulation of translation [GO:0017148]; ossification [GO:0001503]; positive regulation of cardioblast differentiation [GO:0051891]; positive regulation of cytoplasmic translation [GO:2000767]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of gene expression [GO:0010628]; positive regulation of hematopoietic progenitor cell differentiation [GO:1901534]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of intracellular mRNA localization [GO:1904582]; positive regulation of mRNA 3'-end processing [GO:0031442]; positive regulation of myeloid dendritic cell cytokine production [GO:0002735]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of telomere maintenance via telomere lengthening [GO:1904358]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; regulation of embryonic development [GO:0045995]; regulation of mRNA stability [GO:0043488]; regulation of transcription by RNA polymerase III [GO:0006359]; response to exogenous dsRNA [GO:0043330]; RNA secondary structure unwinding [GO:0010501]; spermatogenesis [GO:0007283]; telomerase RNA stabilization [GO:0090669] GO:0000287; GO:0000781; GO:0000978; GO:0001503; GO:0002151; GO:0002735; GO:0003678; GO:0003697; GO:0003723; GO:0003724; GO:0003725; GO:0003730; GO:0005524; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0006359; GO:0007283; GO:0010494; GO:0010501; GO:0010628; GO:0016607; GO:0016887; GO:0017148; GO:0030154; GO:0030424; GO:0030425; GO:0031442; GO:0032727; GO:0034605; GO:0034644; GO:0035925; GO:0042826; GO:0043123; GO:0043204; GO:0043330; GO:0043488; GO:0044806; GO:0045087; GO:0045944; GO:0045995; GO:0048027; GO:0051607; GO:0051880; GO:0051891; GO:0060261; GO:0061003; GO:0061158; GO:0070034; GO:0070883; GO:0090669; GO:1900153; GO:1901534; GO:1903843; GO:1904358; GO:1904582; GO:2000767 1862 XM_044326583.1 323 652 235 407 0 Q80TR8 0 DDB1- and CUL4-associated factor 1 (Serine/threonine-protein kinase VPRBP) (EC 2.7.11.1) Mus musculus (Mouse) B cell differentiation [GO:0030183]; cell competition in a multicellular organism [GO:0035212]; chromatin organization [GO:0006325]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phosphorylation [GO:0016310]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; V(D)J recombination [GO:0033151] GO:0000122; GO:0001650; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0006325; GO:0008180; GO:0016310; GO:0016567; GO:0030183; GO:0030331; GO:0033151; GO:0035212; GO:0043687; GO:0080008; GO:0106310; GO:1990244 1863 XM_044326583.1 323 652 235 407 0 Q80TR8 6.75e-117 DDB1- and CUL4-associated factor 1 (Serine/threonine-protein kinase VPRBP) (EC 2.7.11.1) Mus musculus (Mouse) B cell differentiation [GO:0030183]; cell competition in a multicellular organism [GO:0035212]; chromatin organization [GO:0006325]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phosphorylation [GO:0016310]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; V(D)J recombination [GO:0033151] GO:0000122; GO:0001650; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0006325; GO:0008180; GO:0016310; GO:0016567; GO:0030183; GO:0030331; GO:0033151; GO:0035212; GO:0043687; GO:0080008; GO:0106310; GO:1990244 1864 XM_044314796.1 46 48 3 11 92 NA NA NA NA NA NA 1865 XM_044308003.1 21 30 53 45 33 NA NA NA NA NA NA 1866 XM_029328498.2 674 902 470 270 336 NA NA NA NA NA NA 1867 XM_044326038.1 123 138 85 142 134 Q5M824 1.28e-24 SHC-transforming protein 1 (Src homology 2 domain-containing-transforming protein C1) (SH2 domain protein C1) Rattus norvegicus (Rat) actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; aging [GO:0007568]; angiogenesis [GO:0001525]; animal organ regeneration [GO:0031100]; cell-cell adhesion [GO:0098609]; cellular response to growth factor stimulus [GO:0071363]; cellular response to insulin stimulus [GO:0032869]; defense response to bacterium [GO:0042742]; epidermal growth factor receptor signaling pathway [GO:0007173]; heart development [GO:0007507]; insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009]; intracellular signal transduction [GO:0035556]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-templated transcription [GO:0045892]; neuron differentiation [GO:0030182]; neuron projection development [GO:0031175]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of vasoconstriction [GO:0045907]; regulation of cell population proliferation [GO:0042127]; regulation of smooth muscle contraction [GO:0006940]; response to endothelin [GO:1990839]; response to glucocorticoid [GO:0051384]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to insulin [GO:0032868]; response to nicotine [GO:0035094]; response to organic cyclic compound [GO:0014070]; response to toxic substance [GO:0009636]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0001525; GO:0001666; GO:0001784; GO:0005068; GO:0005154; GO:0005158; GO:0005159; GO:0005168; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0006940; GO:0007169; GO:0007173; GO:0007507; GO:0007568; GO:0008284; GO:0008286; GO:0009636; GO:0010008; GO:0014070; GO:0019901; GO:0030036; GO:0030182; GO:0030971; GO:0031100; GO:0031175; GO:0031532; GO:0032868; GO:0032869; GO:0035094; GO:0035556; GO:0042127; GO:0042542; GO:0042742; GO:0042802; GO:0043066; GO:0043410; GO:0043539; GO:0044877; GO:0045892; GO:0045893; GO:0045907; GO:0046875; GO:0048009; GO:0048408; GO:0048661; GO:0051219; GO:0051384; GO:0051721; GO:0070374; GO:0070435; GO:0071363; GO:0098609; GO:1990839 1868 XM_029355535.2 53 4 59 65 37 Q2UPB1 5.61e-43 Cytochrome P450 monooxygenase aclC (EC 1.-.-.-) (Aspirochlorine biosynthesis protein C) Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold) NA GO:0004497; GO:0005506; GO:0016705; GO:0020037 1869 XM_029357004.2 2029 2246 966 2686 2812 NA NA NA NA NA NA 1870 XM_029329279.2 9 4 0 0 0 P18130 1.02e-47 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) Bos taurus (Bovine) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of vasoconstriction [GO:0045907]; regulation of cardiac muscle contraction [GO:0055117] GO:0001996; GO:0004930; GO:0004937; GO:0005634; GO:0005737; GO:0005886; GO:0005901; GO:0007200; GO:0007204; GO:0007267; GO:0031965; GO:0043410; GO:0045907; GO:0046982; GO:0055117; GO:0071880 1871 XM_029357282.2 55 18 333 59 392 A5PJX7 2.03e-108 Sodium- and chloride-dependent GABA transporter 2 (GAT-2) (Solute carrier family 6 member 13) Bos taurus (Bovine) amino acid import across plasma membrane [GO:0089718]; neurotransmitter transport [GO:0006836]; positive regulation of necrotic cell death [GO:0010940]; sodium ion transmembrane transport [GO:0035725] GO:0005332; GO:0005886; GO:0006836; GO:0010940; GO:0016323; GO:0035725; GO:0043005; GO:0089718 1872 XM_044322511.1 0 17 0 0 25 NA NA NA NA NA NA 1873 XR_006393329.1 8 0 0 0 0 NA NA NA NA NA NA 1874 XM_029348528.2 31 11 32 17 61 Q90WN4 3.08e-50 Forkhead box protein D2 (FoxD2) (xFoxD2) (Fork head domain-related protein 9) (xFD-9) (Forkhead protein 3) (FKH-3) (xFKH3) Xenopus laevis (African clawed frog) regulation of DNA-templated transcription [GO:0006355] GO:0003677; GO:0003700; GO:0005634; GO:0006355; GO:0043565 1875 XR_006393554.1 58 39 2 43 89 NA NA NA NA NA NA 1876 XM_029337389.2 272 48 16 27 35 Q16959 0 Dynein intermediate chain 2, ciliary Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina) NA GO:0005737; GO:0005874; GO:0005929; GO:0030286 1877 XM_029356965.2 1014 1294 742 854 900 Q2HJ56 2.33e-146 Periodic tryptophan protein 1 homolog Bos taurus (Bovine) negative regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033140]; positive regulation of stem cell differentiation [GO:2000738]; positive regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901838]; rRNA processing [GO:0006364] GO:0005634; GO:0005694; GO:0005730; GO:0005794; GO:0006364; GO:0033140; GO:0140713; GO:1901838; GO:1990889; GO:2000738 1878 XM_029338422.2 1296 1185 650 1205 1789 Q0IIF7 0 Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.4.19.12) (Deubiquitinating enzyme 14) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) Bos taurus (Bovine) innate immune response [GO:0045087]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; regulation of proteasomal protein catabolic process [GO:0061136] GO:0000502; GO:0004843; GO:0005737; GO:0005886; GO:0016579; GO:0043161; GO:0045087; GO:0061136; GO:0070628 1879 XM_029342537.2 107 75 0 25 38 Q9EQD2 1.85e-33 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 1880 XM_044312120.1 0 35 46 90 0 Q05941 6.45e-79 Neuronal acetylcholine receptor subunit alpha-7 Rattus norvegicus (Rat) acetylcholine receptor signaling pathway [GO:0095500]; associative learning [GO:0008306]; B cell activation [GO:0042113]; behavioral response to ethanol [GO:0048149]; behavioral response to nicotine [GO:0035095]; calcium ion transport [GO:0006816]; cation transmembrane transport [GO:0098655]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; cognition [GO:0050890]; dendrite arborization [GO:0140059]; dendritic spine organization [GO:0097061]; dopamine biosynthetic process [GO:0042416]; endocytosis [GO:0006897]; establishment of localization in cell [GO:0051649]; excitatory postsynaptic potential [GO:0060079]; flagellated sperm motility [GO:0030317]; generation of ovulation cycle rhythm [GO:0060112]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; learning or memory [GO:0007611]; membrane depolarization [GO:0051899]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; modulation of excitatory postsynaptic potential [GO:0098815]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of tumor necrosis factor production [GO:0032720]; nervous system process [GO:0050877]; neuronal action potential [GO:0019228]; ovulation cycle [GO:0042698]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of CoA-transferase activity [GO:1905920]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure [GO:0001988]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of amyloid fibril formation [GO:1905906]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of inflammatory response [GO:0050727]; regulation of membrane potential [GO:0042391]; regulation of neuron death [GO:1901214]; regulation of nitric oxide metabolic process [GO:0080164]; regulation of norepinephrine secretion [GO:0014061]; regulation of response to drug [GO:2001023]; regulation of synaptic transmission, dopaminergic [GO:0032225]; response to acetylcholine [GO:1905144]; response to amyloid-beta [GO:1904645]; response to carbamate [GO:0046681]; response to cold [GO:0009409]; response to ethanol [GO:0045471]; response to food [GO:0032094]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; sensory processing [GO:0050893]; signal transduction [GO:0007165]; synapse organization [GO:0050808]; synaptic transmission, cholinergic [GO:0007271]; T cell activation [GO:0042110] GO:0001540; GO:0001666; GO:0001933; GO:0001934; GO:0001988; GO:0005216; GO:0005231; GO:0005737; GO:0005886; GO:0005892; GO:0006811; GO:0006816; GO:0006874; GO:0006897; GO:0007165; GO:0007268; GO:0007271; GO:0007611; GO:0007613; GO:0008179; GO:0008284; GO:0008306; GO:0009409; GO:0009897; GO:0010628; GO:0014061; GO:0014069; GO:0015464; GO:0015643; GO:0016020; GO:0016324; GO:0017081; GO:0019228; GO:0019901; GO:0022848; GO:0030317; GO:0030424; GO:0030425; GO:0030426; GO:0030594; GO:0030673; GO:0032094; GO:0032225; GO:0032279; GO:0032691; GO:0032715; GO:0032720; GO:0033138; GO:0034220; GO:0035094; GO:0035095; GO:0042110; GO:0042113; GO:0042166; GO:0042391; GO:0042416; GO:0042698; GO:0042734; GO:0042803; GO:0043005; GO:0043025; GO:0043197; GO:0043198; GO:0043410; GO:0044853; GO:0045121; GO:0045202; GO:0045211; GO:0045471; GO:0045766; GO:0046681; GO:0048149; GO:0050727; GO:0050728; GO:0050804; GO:0050808; GO:0050877; GO:0050890; GO:0050893; GO:0051117; GO:0051247; GO:0051649; GO:0051899; GO:0060079; GO:0060112; GO:0070373; GO:0070374; GO:0080164; GO:0095500; GO:0097061; GO:0097110; GO:0098655; GO:0098690; GO:0098815; GO:0098897; GO:0098981; GO:0099171; GO:0099634; GO:0140059; GO:1900273; GO:1901214; GO:1902004; GO:1902430; GO:1902991; GO:1904315; GO:1904645; GO:1905144; GO:1905906; GO:1905920; GO:2000463; GO:2001023 1881 XM_029330430.2 121 60 57 87 176 NA NA NA NA NA NA 1882 XM_029353976.2 26 5 12 1 91 NA NA NA NA NA NA 1883 XM_029344172.2 70 0 46 43 15 NA NA NA NA NA NA 1884 XM_029328886.2 1819 1696 1258 2069 1965 A3KMV2 3.63e-69 UV excision repair protein RAD23 homolog A Bos taurus (Bovine) nucleotide-excision repair [GO:0006289]; positive regulation of cell cycle [GO:0045787]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of viral genome replication [GO:0045070]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein destabilization [GO:0031648] GO:0000502; GO:0003684; GO:0005654; GO:0005794; GO:0005829; GO:0006289; GO:0019900; GO:0031593; GO:0031648; GO:0032436; GO:0043130; GO:0043161; GO:0045070; GO:0045787; GO:0070628; GO:1990381 1885 XR_006397090.1 978 898 1441 1079 706 NA NA NA NA NA NA 1886 XM_044313360.1 0 0 0 4 13 NA NA NA NA NA NA 1887 XM_029340316.2 653 398 378 363 507 Q13322 2.98e-64 Growth factor receptor-bound protein 10 (GRB10 adapter protein) (Insulin receptor-binding protein Grb-IR) Homo sapiens (Human) ERK1 and ERK2 cascade [GO:0070371]; gene expression [GO:0010467]; insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009]; negative regulation of glucose import [GO:0046325]; negative regulation of glycogen biosynthetic process [GO:0045719]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of phosphorylation [GO:0042326]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of phosphorylation [GO:0042327]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; response to insulin [GO:0032868]; vascular associated smooth muscle cell migration [GO:1904738] GO:0005158; GO:0005737; GO:0005829; GO:0005886; GO:0008286; GO:0010467; GO:0030159; GO:0030178; GO:0030949; GO:0032868; GO:0032991; GO:0042326; GO:0042327; GO:0042802; GO:0045719; GO:0046325; GO:0046627; GO:0048009; GO:0070371; GO:0120162; GO:1904738 1888 XM_044325324.1 469 295 222 371 267 Q8JGM4 1.82e-116 Sulfhydryl oxidase 1 (EC 1.8.3.2) (Quiescin Q6) Gallus gallus (Chicken) protein folding [GO:0006457] GO:0000139; GO:0003756; GO:0005615; GO:0006457; GO:0016971 1889 XM_029357124.2 51 33 48 21 57 NA NA NA NA NA NA 1890 XM_044324580.1 6 2 4 89 24 A2AJ76 4.77e-24 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 1891 XM_044324580.1 6 2 4 89 24 A2AJ76 3.28e-22 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 1892 XM_044324580.1 6 2 4 89 24 A2AJ76 1.56e-21 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 1893 XM_044313100.1 3525 1945 1666 73 2160 NA NA NA NA NA NA 1894 XM_044329006.1 216 96 83 149 308 P60670 0 Nuclear protein localization protein 4 homolog (Protein NPL4) Mus musculus (Mouse) Golgi organization [GO:0007030]; negative regulation of RIG-I signaling pathway [GO:0039536]; negative regulation of type I interferon production [GO:0032480]; retrograde protein transport, ER to cytosol [GO:0030970]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0005634; GO:0005783; GO:0005829; GO:0006511; GO:0007030; GO:0030433; GO:0030970; GO:0031625; GO:0032480; GO:0034098; GO:0036435; GO:0036501; GO:0039536; GO:0042175; GO:0043130; GO:0044877; GO:0046872; GO:0051117; GO:0070530 1895 XM_029340054.2 2243 2342 1823 3118 1838 Q6DFV5 8.39e-111 Probable helicase with zinc finger domain (EC 3.6.4.-) Mus musculus (Mouse) RNA-mediated post-transcriptional gene silencing [GO:0035194] GO:0003723; GO:0004386; GO:0005524; GO:0005634; GO:0005829; GO:0016787; GO:0035194; GO:0043186; GO:0046872 1896 XM_044321343.1 0 0 20 77 69 P46023 2.22e-91 G-protein coupled receptor GRL101 Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004930; GO:0005886 1897 XM_044322401.1 48 0 107 76 56 Q96AY4 4.9e-94 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1898 XM_044322401.1 48 0 107 76 56 Q96AY4 2.04e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1899 XM_044322401.1 48 0 107 76 56 Q96AY4 2.28e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1900 XM_044322401.1 48 0 107 76 56 Q96AY4 1.86e-83 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1901 XM_044322401.1 48 0 107 76 56 Q96AY4 3.55e-83 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1902 XM_044322401.1 48 0 107 76 56 Q96AY4 8.22e-82 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1903 XM_044322401.1 48 0 107 76 56 Q96AY4 1.84e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1904 XM_044311866.1 8 4 5 18 16 NA NA NA NA NA NA 1905 XM_044325908.1 0 0 0 144 4 NA NA NA NA NA NA 1906 XM_029338373.2 2736 2206 1422 2819 2923 Q496Y0 4.6e-77 LON peptidase N-terminal domain and RING finger protein 3 (RING finger protein 127) Homo sapiens (Human) NA GO:0005737; GO:0046872; GO:0061630 1907 XM_044318244.1 347 198 171 230 423 Q9HAR2 9.93e-67 Adhesion G protein-coupled receptor L3 (Calcium-independent alpha-latrotoxin receptor 3) (CIRL-3) (Latrophilin-3) (Lectomedin-3) Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; brain development [GO:0007420]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; G protein-coupled receptor signaling pathway [GO:0007186]; neuron migration [GO:0001764]; synapse assembly [GO:0007416] GO:0001764; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007166; GO:0007186; GO:0007189; GO:0007416; GO:0007420; GO:0016020; GO:0030246; GO:0030424; GO:0098742; GO:0098978 1908 XM_029323570.2 1427 990 673 1462 1171 O75131 0 Copine-3 (Copine III) Homo sapiens (Human) cellular response to calcium ion [GO:0071277]; cellular response to growth factor stimulus [GO:0071363]; ERBB2 signaling pathway [GO:0038128]; positive regulation of cell migration [GO:0030335] GO:0003723; GO:0004674; GO:0005544; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005739; GO:0005829; GO:0005886; GO:0005925; GO:0030054; GO:0030335; GO:0030971; GO:0035577; GO:0038128; GO:0046872; GO:0048306; GO:0070062; GO:0071277; GO:0071363 1909 XM_029351486.2 0 0 63 0 0 Q5TZA2 7.41e-67 Rootletin (Ciliary rootlet coiled-coil protein) Homo sapiens (Human) cellular homeostasis [GO:0019725]; centriole-centriole cohesion [GO:0010457]; centrosome cycle [GO:0007098]; ciliary basal body organization [GO:0032053]; epithelial structure maintenance [GO:0010669]; establishment of localization in cell [GO:0051649]; establishment of organelle localization [GO:0051656]; photoreceptor cell maintenance [GO:0045494]; positive regulation of cilium assembly [GO:0045724]; positive regulation of protein localization to cilium [GO:1903566]; protein localization [GO:0008104]; protein localization to organelle [GO:0033365] GO:0001917; GO:0003779; GO:0005198; GO:0005200; GO:0005813; GO:0005814; GO:0005829; GO:0005886; GO:0007098; GO:0008104; GO:0010457; GO:0010669; GO:0015629; GO:0019725; GO:0019894; GO:0032053; GO:0033365; GO:0035253; GO:0045494; GO:0045724; GO:0051649; GO:0051656; GO:0070062; GO:0097729; GO:0120219; GO:1903566 1910 XM_044315032.1 0 190 0 0 0 NA NA NA NA NA NA 1911 XR_006393340.1 46 59 31 34 67 NA NA NA NA NA NA 1912 XR_006397257.1 10 4 0 0 0 NA NA NA NA NA NA 1913 XR_006391982.1 17 277 0 172 31 NA NA NA NA NA NA 1914 XM_029337627.2 166 138 124 182 266 NA NA NA NA NA NA 1915 XM_044314414.1 29 63 121 120 17 NA NA NA NA NA NA 1916 XM_029356926.2 1039 1378 820 1595 1491 Q28728 2.09e-144 Sodium/myo-inositol cotransporter 2 (Na(+)/myo-inositol cotransporter 2) (Sodium-dependent glucose cotransporter) (Sodium/glucose cotransporter KST1) (rKST1) (Sodium/myo-inositol transporter 2) (SMIT2) (Solute carrier family 5 member 11) Oryctolagus cuniculus (Rabbit) apoptotic process [GO:0006915]; carbohydrate transport [GO:0008643]; myo-inositol transport [GO:0015798]; regulation of transporter activity [GO:0032409]; sodium ion transport [GO:0006814] GO:0005365; GO:0005886; GO:0006814; GO:0006915; GO:0008643; GO:0015293; GO:0015798; GO:0016324; GO:0032409 1917 XM_029336299.2 1142 740 668 580 354 P83851 2.38e-41 Inosine-uridine preferring nucleoside hydrolase (IU-NH) (IU-nucleoside hydrolase) (EC 3.2.2.2) (EC 3.2.2.3) (Non-specific nucleoside hydrolase) Leishmania major nucleotide metabolic process [GO:0009117]; purine-containing compound salvage [GO:0043101] GO:0005509; GO:0008477; GO:0009117; GO:0043101; GO:0045437; GO:0047724 1918 XM_029358691.2 246 229 281 296 713 P60330 7.17e-83 Separin (EC 3.4.22.49) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein) (Separase) Mus musculus (Mouse) chromosome segregation [GO:0007059]; homologous chromosome segregation [GO:0045143]; meiosis I [GO:0007127]; meiotic chromosome separation [GO:0051307]; meiotic spindle organization [GO:0000212]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; proteolysis [GO:0006508] GO:0000070; GO:0000212; GO:0000278; GO:0004197; GO:0005634; GO:0005737; GO:0005813; GO:0006508; GO:0007059; GO:0007127; GO:0008233; GO:0008234; GO:0045143; GO:0051307; GO:0072686 1919 XM_029345658.2 279 287 218 362 368 Q75N90 3.87e-45 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 1920 XM_029345658.2 279 287 218 362 368 Q75N90 1.01e-38 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 1921 XM_029345658.2 279 287 218 362 368 Q75N90 4.38e-33 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 1922 XM_029345658.2 279 287 218 362 368 Q75N90 5.48e-32 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 1923 XM_029345658.2 279 287 218 362 368 Q75N90 2.01e-28 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 1924 XM_029345658.2 279 287 218 362 368 Q75N90 2.16e-28 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 1925 XM_029345658.2 279 287 218 362 368 Q75N90 6.24e-28 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 1926 XM_029345658.2 279 287 218 362 368 Q75N90 1.17e-26 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 1927 XM_029345658.2 279 287 218 362 368 Q75N90 1.94e-23 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 1928 XM_029345658.2 279 287 218 362 368 Q75N90 4.42e-23 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 1929 XM_029345658.2 279 287 218 362 368 Q75N90 2.12e-22 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 1930 XM_029345658.2 279 287 218 362 368 Q75N90 4.96e-22 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 1931 XM_029345658.2 279 287 218 362 368 Q75N90 1.2e-21 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 1932 XM_029354781.2 1299 1062 714 1067 1101 Q0VD26 1.74e-41 MORN repeat-containing protein 4 (Retinophilin) Bos taurus (Bovine) response to axon injury [GO:0048678] GO:0005737; GO:0032426; GO:0032433; GO:0042995; GO:0048678 1933 XM_044311339.1 19 422 187 17 14 Q8I913 2.77e-56 Dermonecrotic toxin LlSicTox-alphaIII3i (EC 4.6.1.-) (LlH13) (Phospholipase D) (PLD) (Sphingomyelin phosphodiesterase D) (SMD) (SMase D) (Sphingomyelinase D) Loxosceles laeta (South American recluse spider) (Scytodes laeta) hemolysis in another organism [GO:0044179]; lipid catabolic process [GO:0016042] GO:0005576; GO:0008081; GO:0016042; GO:0016829; GO:0044179; GO:0046872; GO:0090729 1934 XM_044321267.1 615 377 182 318 465 NA NA NA NA NA NA 1935 XR_006394795.1 2 8 10 7 17 NA NA NA NA NA NA 1936 XM_029356885.2 41 63 102 41 106 P61752 1.65e-28 Histamine H2 receptor (H2R) (HH2R) (Gastric receptor I) Pongo pygmaeus (Bornean orangutan) gastric acid secretion [GO:0001696]; positive regulation of vasoconstriction [GO:0045907] GO:0001696; GO:0004969; GO:0005886; GO:0045907 1937 XM_044315932.1 0 0 8 1 6 NA NA NA NA NA NA 1938 XM_029347763.2 16 72 28 231 404 NA NA NA NA NA NA 1939 XM_029338751.2 3161 2599 1392 3077 2948 Q99JY0 0 Trifunctional enzyme subunit beta, mitochondrial (TP-beta) [Includes: 3-ketoacyl-CoA thiolase (EC 2.3.1.155) (EC 2.3.1.16) (Acetyl-CoA acyltransferase) (Beta-ketothiolase)] Mus musculus (Mouse) cellular response to lipopolysaccharide [GO:0071222]; fatty acid beta-oxidation [GO:0006635]; gene expression [GO:0010467] GO:0003985; GO:0003988; GO:0005739; GO:0005741; GO:0005743; GO:0005783; GO:0006635; GO:0010467; GO:0016507; GO:0042645; GO:0044877; GO:0050633; GO:0071222; GO:0106222 1940 XM_029333080.2 60 53 52 0 35 Q0V8E4 9.47e-116 Asparagine synthetase domain-containing protein 1 Bos taurus (Bovine) asparagine biosynthetic process [GO:0006529]; glutamine metabolic process [GO:0006541] GO:0004066; GO:0006529; GO:0006541 1941 XM_029333080.2 60 53 52 0 35 Q0V8E4 2.26e-23 Asparagine synthetase domain-containing protein 1 Bos taurus (Bovine) asparagine biosynthetic process [GO:0006529]; glutamine metabolic process [GO:0006541] GO:0004066; GO:0006529; GO:0006541 1942 XM_044326855.1 24 19 102 60 301 NA NA NA NA NA NA 1943 XM_044317120.1 4450 786 1422 543 818 NA NA NA NA NA NA 1944 XM_044308370.1 1649 1041 1275 1540 2245 Q0E9H9 2.72e-22 NA NA NA NA 1945 XM_029357202.2 223 82 167 184 82 NA NA NA NA NA NA 1946 XM_044317536.1 97 80 30 171 162 NA NA NA NA NA NA 1947 XM_044319174.1 471 328 336 505 323 Q9R0M0 1.68e-73 Cadherin EGF LAG seven-pass G-type receptor 2 (Flamingo homolog) Mus musculus (Mouse) cell-cell adhesion [GO:0098609]; cerebrospinal fluid secretion [GO:0033326]; cilium assembly [GO:0060271]; cilium movement [GO:0003341]; dendrite morphogenesis [GO:0048813]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; neural plate anterior/posterior regionalization [GO:0021999]; regulation of cell-cell adhesion [GO:0022407]; regulation of DNA-templated transcription [GO:0006355]; regulation of protein localization [GO:0032880]; ventricular system development [GO:0021591]; Wnt signaling pathway [GO:0016055] GO:0003341; GO:0004930; GO:0005509; GO:0005737; GO:0005886; GO:0006355; GO:0007156; GO:0016055; GO:0021591; GO:0021999; GO:0022407; GO:0032880; GO:0033326; GO:0048813; GO:0060271; GO:0097475; GO:0098609 1948 XM_044319174.1 471 328 336 505 323 Q9R0M0 1.14e-60 Cadherin EGF LAG seven-pass G-type receptor 2 (Flamingo homolog) Mus musculus (Mouse) cell-cell adhesion [GO:0098609]; cerebrospinal fluid secretion [GO:0033326]; cilium assembly [GO:0060271]; cilium movement [GO:0003341]; dendrite morphogenesis [GO:0048813]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; neural plate anterior/posterior regionalization [GO:0021999]; regulation of cell-cell adhesion [GO:0022407]; regulation of DNA-templated transcription [GO:0006355]; regulation of protein localization [GO:0032880]; ventricular system development [GO:0021591]; Wnt signaling pathway [GO:0016055] GO:0003341; GO:0004930; GO:0005509; GO:0005737; GO:0005886; GO:0006355; GO:0007156; GO:0016055; GO:0021591; GO:0021999; GO:0022407; GO:0032880; GO:0033326; GO:0048813; GO:0060271; GO:0097475; GO:0098609 1949 XM_044319174.1 471 328 336 505 323 Q9R0M0 8.43e-59 Cadherin EGF LAG seven-pass G-type receptor 2 (Flamingo homolog) Mus musculus (Mouse) cell-cell adhesion [GO:0098609]; cerebrospinal fluid secretion [GO:0033326]; cilium assembly [GO:0060271]; cilium movement [GO:0003341]; dendrite morphogenesis [GO:0048813]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; neural plate anterior/posterior regionalization [GO:0021999]; regulation of cell-cell adhesion [GO:0022407]; regulation of DNA-templated transcription [GO:0006355]; regulation of protein localization [GO:0032880]; ventricular system development [GO:0021591]; Wnt signaling pathway [GO:0016055] GO:0003341; GO:0004930; GO:0005509; GO:0005737; GO:0005886; GO:0006355; GO:0007156; GO:0016055; GO:0021591; GO:0021999; GO:0022407; GO:0032880; GO:0033326; GO:0048813; GO:0060271; GO:0097475; GO:0098609 1950 XM_044319174.1 471 328 336 505 323 Q9R0M0 3e-58 Cadherin EGF LAG seven-pass G-type receptor 2 (Flamingo homolog) Mus musculus (Mouse) cell-cell adhesion [GO:0098609]; cerebrospinal fluid secretion [GO:0033326]; cilium assembly [GO:0060271]; cilium movement [GO:0003341]; dendrite morphogenesis [GO:0048813]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; neural plate anterior/posterior regionalization [GO:0021999]; regulation of cell-cell adhesion [GO:0022407]; regulation of DNA-templated transcription [GO:0006355]; regulation of protein localization [GO:0032880]; ventricular system development [GO:0021591]; Wnt signaling pathway [GO:0016055] GO:0003341; GO:0004930; GO:0005509; GO:0005737; GO:0005886; GO:0006355; GO:0007156; GO:0016055; GO:0021591; GO:0021999; GO:0022407; GO:0032880; GO:0033326; GO:0048813; GO:0060271; GO:0097475; GO:0098609 1951 XM_044319174.1 471 328 336 505 323 Q9R0M0 7.59e-55 Cadherin EGF LAG seven-pass G-type receptor 2 (Flamingo homolog) Mus musculus (Mouse) cell-cell adhesion [GO:0098609]; cerebrospinal fluid secretion [GO:0033326]; cilium assembly [GO:0060271]; cilium movement [GO:0003341]; dendrite morphogenesis [GO:0048813]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; neural plate anterior/posterior regionalization [GO:0021999]; regulation of cell-cell adhesion [GO:0022407]; regulation of DNA-templated transcription [GO:0006355]; regulation of protein localization [GO:0032880]; ventricular system development [GO:0021591]; Wnt signaling pathway [GO:0016055] GO:0003341; GO:0004930; GO:0005509; GO:0005737; GO:0005886; GO:0006355; GO:0007156; GO:0016055; GO:0021591; GO:0021999; GO:0022407; GO:0032880; GO:0033326; GO:0048813; GO:0060271; GO:0097475; GO:0098609 1952 XM_044319174.1 471 328 336 505 323 Q9R0M0 3.94e-51 Cadherin EGF LAG seven-pass G-type receptor 2 (Flamingo homolog) Mus musculus (Mouse) cell-cell adhesion [GO:0098609]; cerebrospinal fluid secretion [GO:0033326]; cilium assembly [GO:0060271]; cilium movement [GO:0003341]; dendrite morphogenesis [GO:0048813]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; neural plate anterior/posterior regionalization [GO:0021999]; regulation of cell-cell adhesion [GO:0022407]; regulation of DNA-templated transcription [GO:0006355]; regulation of protein localization [GO:0032880]; ventricular system development [GO:0021591]; Wnt signaling pathway [GO:0016055] GO:0003341; GO:0004930; GO:0005509; GO:0005737; GO:0005886; GO:0006355; GO:0007156; GO:0016055; GO:0021591; GO:0021999; GO:0022407; GO:0032880; GO:0033326; GO:0048813; GO:0060271; GO:0097475; GO:0098609 1953 XM_029335710.2 0 0 242 520 0 Q9NZM1 0 Myoferlin (Fer-1-like protein 3) Homo sapiens (Human) blood circulation [GO:0008015]; membrane fusion [GO:0061025]; muscle contraction [GO:0006936]; plasma membrane organization [GO:0007009]; plasma membrane repair [GO:0001778]; T-tubule organization [GO:0033292] GO:0001778; GO:0005543; GO:0005635; GO:0005886; GO:0005901; GO:0006936; GO:0007009; GO:0008015; GO:0030659; GO:0031410; GO:0031965; GO:0033292; GO:0043231; GO:0046872; GO:0061025; GO:0070062 1954 XM_029358269.2 84 36 74 108 239 Q7TN88 1.38e-64 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 1955 XM_029358269.2 84 36 74 108 239 Q7TN88 8.91e-45 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 1956 XM_044319348.1 575 782 375 577 433 Q6PHS6 0 Sorting nexin-13 Mus musculus (Mouse) intracellular protein transport [GO:0006886]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547] GO:0005769; GO:0006886; GO:0009968; GO:0031901; GO:0032266; GO:0035091; GO:0043231; GO:0043547 1957 XM_044308911.1 272 0 22 0 154 NA NA NA NA NA NA 1958 XM_044323965.1 865 567 821 1225 1917 P98133 0 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 1959 XM_044323965.1 865 567 821 1225 1917 P98133 0 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 1960 XM_044323965.1 865 567 821 1225 1917 P98133 0 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 1961 XM_044323965.1 865 567 821 1225 1917 P98133 0 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 1962 XM_044323965.1 865 567 821 1225 1917 P98133 0 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 1963 XM_044323965.1 865 567 821 1225 1917 P98133 0 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 1964 XM_044323965.1 865 567 821 1225 1917 P98133 9.82e-171 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 1965 XM_044323965.1 865 567 821 1225 1917 P98133 1.05e-165 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 1966 XM_044323965.1 865 567 821 1225 1917 P98133 9.12e-163 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 1967 XM_044323965.1 865 567 821 1225 1917 P98133 1.09e-155 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 1968 XM_044323965.1 865 567 821 1225 1917 P98133 8.32e-133 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 1969 XM_044323965.1 865 567 821 1225 1917 P98133 5.16e-115 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 1970 XM_029325006.2 3381 7101 3996 5960 4742 NA NA NA NA NA NA 1971 XR_006392745.1 19 0 0 0 0 NA NA NA NA NA NA 1972 XM_029342250.2 672 569 355 728 806 Q96K37 1.74e-97 Solute carrier family 35 member E1 Homo sapiens (Human) NA GO:0005794; GO:0015297; GO:0016020 1973 XM_029329440.2 1216 1098 787 1354 1309 Q2HJ86 0 Tubulin alpha-1D chain (EC 3.6.5.-) [Cleaved into: Detyrosinated tubulin alpha-1D chain] Bos taurus (Bovine) microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278] GO:0000226; GO:0000278; GO:0005200; GO:0005525; GO:0005737; GO:0005874; GO:0016787; GO:0046872 1974 XM_044324442.1 39 30 34 78 149 NA NA NA NA NA NA 1975 XR_006394133.1 75 51 269 44 694 NA NA NA NA NA NA 1976 XR_006398184.1 20 12 26 16 50 NA NA NA NA NA NA 1977 XM_029346129.2 3206 3510 2554 1763 2471 D3ZVP7 1.63e-47 Zinc finger FYVE domain-containing protein 21 Rattus norvegicus (Rat) NA GO:0005768; GO:0005925; GO:0046872 1978 XM_029334228.2 360 132 192 343 345 Q5ZIM6 2.64e-74 Protein AATF (Apoptosis-antagonizing transcription factor) Gallus gallus (Chicken) regulation of transcription by RNA polymerase II [GO:0006357] GO:0005730; GO:0006357 1979 XM_044320758.1 45 0 29 8 78 Q8CG19 1.98e-33 Latent-transforming growth factor beta-binding protein 1 (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1) Mus musculus (Mouse) aorta development [GO:0035904]; coronary vasculature development [GO:0060976]; positive regulation of collagen biosynthetic process [GO:0032967]; regulation of transforming growth factor beta activation [GO:1901388]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ventricular septum development [GO:0003281] GO:0001527; GO:0003281; GO:0005509; GO:0005576; GO:0005737; GO:0005739; GO:0007179; GO:0030425; GO:0031012; GO:0032967; GO:0032991; GO:0035583; GO:0035904; GO:0038045; GO:0043025; GO:0048471; GO:0050431; GO:0050436; GO:0060976; GO:0062023; GO:1901388 1980 XM_044320758.1 45 0 29 8 78 Q8CG19 1.59e-25 Latent-transforming growth factor beta-binding protein 1 (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1) Mus musculus (Mouse) aorta development [GO:0035904]; coronary vasculature development [GO:0060976]; positive regulation of collagen biosynthetic process [GO:0032967]; regulation of transforming growth factor beta activation [GO:1901388]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ventricular septum development [GO:0003281] GO:0001527; GO:0003281; GO:0005509; GO:0005576; GO:0005737; GO:0005739; GO:0007179; GO:0030425; GO:0031012; GO:0032967; GO:0032991; GO:0035583; GO:0035904; GO:0038045; GO:0043025; GO:0048471; GO:0050431; GO:0050436; GO:0060976; GO:0062023; GO:1901388 1981 XM_029350657.2 3508 4799 3055 3930 3237 P62315 1.99e-47 Small nuclear ribonucleoprotein Sm D1 (Sm-D1) (Sm-D autoantigen) (snRNP core protein D1) Mus musculus (Mouse) mRNA splicing, via spliceosome [GO:0000398]; spliceosomal snRNP assembly [GO:0000387] GO:0000243; GO:0000387; GO:0000398; GO:0003723; GO:0005634; GO:0005681; GO:0005682; GO:0005685; GO:0005686; GO:0005687; GO:0005689; GO:0005737; GO:0005829; GO:0034709; GO:0034715; GO:0034719; GO:0046540; GO:0071005; GO:0071007; GO:0071011; GO:0071013; GO:0097526; GO:1990446 1982 XM_044320489.1 155 1 9 0 0 Q9UNA1 5.5e-170 Rho GTPase-activating protein 26 (GTPase regulator associated with focal adhesion kinase) (Oligophrenin-1-like protein) (Rho-type GTPase-activating protein 26) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; nervous system development [GO:0007399]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] GO:0005096; GO:0005543; GO:0005829; GO:0005856; GO:0005925; GO:0007165; GO:0007399; GO:0030036; GO:0051056 1983 XM_044321403.1 5 1 8 9 7 O95704 5.66e-39 Amyloid-beta A4 precursor protein-binding family B member 3 (Protein Fe65-like 2) (Fe65L2) Homo sapiens (Human) positive regulation of protein secretion [GO:0050714]; regulation of DNA-templated transcription [GO:0006355] GO:0001540; GO:0005634; GO:0005737; GO:0005829; GO:0006355; GO:0015629; GO:0016020; GO:0050714; GO:0050750 1984 XM_044321545.1 0 0 0 0 35 NA NA NA NA NA NA 1985 XM_044321782.1 0 28 29 58 61 NA NA NA NA NA NA 1986 XM_029330415.2 38 0 0 108 0 Q9EQD2 1.54e-37 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 1987 XM_044328631.1 142 122 81 130 198 P54145 1.32e-85 Putative ammonium transporter 1 Caenorhabditis elegans ammonium homeostasis [GO:0097272]; ammonium transmembrane transport [GO:0072488] GO:0005886; GO:0008519; GO:0072488; GO:0097272 1988 XM_029355666.2 1723 824 652 926 581 A4IFB6 0 CCR4-NOT transcription complex subunit 10 Bos taurus (Bovine) mRNA catabolic process [GO:0006402]; negative regulation of translation [GO:0017148] GO:0006402; GO:0017148; GO:0030014 1989 XM_029342356.2 3782 1939 1016 1384 3069 P98156 3.55e-160 Very low-density lipoprotein receptor (VLDL receptor) (VLDL-R) Mus musculus (Mouse) cellular response to hypoxia [GO:0071456]; cholesterol metabolic process [GO:0008203]; dendrite morphogenesis [GO:0048813]; glycoprotein transport [GO:0034436]; lipid transport [GO:0006869]; positive regulation of dendrite development [GO:1900006]; positive regulation of protein kinase activity [GO:0045860]; receptor-mediated endocytosis [GO:0006898]; reelin-mediated signaling pathway [GO:0038026]; ventral spinal cord development [GO:0021517]; very-low-density lipoprotein particle clearance [GO:0034447] GO:0005509; GO:0005615; GO:0005634; GO:0005886; GO:0005905; GO:0006869; GO:0006898; GO:0008203; GO:0009986; GO:0016020; GO:0021517; GO:0030229; GO:0034185; GO:0034189; GO:0034361; GO:0034436; GO:0034447; GO:0038024; GO:0038025; GO:0038026; GO:0043235; GO:0045177; GO:0045860; GO:0048306; GO:0048471; GO:0048813; GO:0071456; GO:1900006 1990 XR_006394341.1 0 2 1 23 13 NA NA NA NA NA NA 1991 XM_029344046.2 117 168 231 352 178 NA NA NA NA NA NA 1992 XM_044323594.1 188 2 6 4 8 NA NA NA NA NA NA 1993 XM_044322729.1 0 6 2 15 0 NA NA NA NA NA NA 1994 XM_029335680.2 96 4 42 42 105 P07314 8.36e-137 Glutathione hydrolase 1 proenzyme (EC 3.4.19.13) (Gamma-glutamyltransferase 1) (Gamma-glutamyltranspeptidase 1) (GGT 1) (EC 2.3.2.2) (Leukotriene-C4 hydrolase) (EC 3.4.19.14) (CD antigen CD224) [Cleaved into: Glutathione hydrolase 1 heavy chain; Glutathione hydrolase 1 light chain] Rattus norvegicus (Rat) aging [GO:0007568]; amino acid metabolic process [GO:0006520]; cellular response to oxidative stress [GO:0034599]; cysteine biosynthetic process [GO:0019344]; fatty acid metabolic process [GO:0006631]; glutamate metabolic process [GO:0006536]; glutathione biosynthetic process [GO:0006750]; glutathione catabolic process [GO:0006751]; hepatoblast differentiation [GO:0061017]; hepatocyte differentiation [GO:0070365]; leukotriene D4 biosynthetic process [GO:1901750]; leukotriene metabolic process [GO:0006691]; liver regeneration [GO:0097421]; peptide modification [GO:0031179]; proteolysis [GO:0006508]; regulation of immune system process [GO:0002682]; regulation of inflammatory response [GO:0050727]; response to alcohol [GO:0097305]; response to estradiol [GO:0032355]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]; spermatogenesis [GO:0007283]; zymogen activation [GO:0031638] GO:0000048; GO:0002682; GO:0002951; GO:0005615; GO:0005886; GO:0006508; GO:0006520; GO:0006536; GO:0006631; GO:0006691; GO:0006750; GO:0006751; GO:0007283; GO:0007568; GO:0016755; GO:0019344; GO:0031179; GO:0031638; GO:0031982; GO:0032355; GO:0032496; GO:0034599; GO:0034612; GO:0036374; GO:0050727; GO:0061017; GO:0070365; GO:0097305; GO:0097421; GO:0102953; GO:0103068; GO:1901750 1995 XM_044311623.1 7 26 7 2 14 NA NA NA NA NA NA 1996 XM_044326887.1 10 4 2 10 1 NA NA NA NA NA NA 1997 XR_006391297.1 197 55 71 228 359 NA NA NA NA NA NA 1998 XM_029338632.2 6003 3378 5695 4499 5441 Q99571 3.26e-109 P2X purinoceptor 4 (P2X4) (ATP receptor) (Purinergic receptor) Homo sapiens (Human) apoptotic signaling pathway [GO:0097190]; behavioral response to pain [GO:0048266]; calcium ion transmembrane transport [GO:0070588]; calcium-mediated signaling [GO:0019722]; cellular response to ATP [GO:0071318]; cellular response to zinc ion [GO:0071294]; endothelial cell activation [GO:0042118]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; neuronal action potential [GO:0019228]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of microglial cell migration [GO:1904141]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein kinase B signaling [GO:0051897]; purinergic nucleotide receptor signaling pathway [GO:0035590]; regulation of blood pressure [GO:0008217]; regulation of cardiac muscle contraction [GO:0055117]; regulation of chemotaxis [GO:0050920]; regulation of sodium ion transport [GO:0002028]; relaxation of cardiac muscle [GO:0055119]; response to ATP [GO:0033198]; response to axon injury [GO:0048678]; response to fluid shear stress [GO:0034405]; response to ischemia [GO:0002931]; sensory perception of pain [GO:0019233]; sensory perception of touch [GO:0050975]; signal transduction [GO:0007165]; tissue homeostasis [GO:0001894] GO:0001614; GO:0001894; GO:0002028; GO:0002931; GO:0004931; GO:0005102; GO:0005507; GO:0005524; GO:0005637; GO:0005765; GO:0005886; GO:0007165; GO:0008217; GO:0008270; GO:0010524; GO:0010614; GO:0014069; GO:0016020; GO:0019228; GO:0019233; GO:0019722; GO:0030054; GO:0032308; GO:0033198; GO:0034220; GO:0034405; GO:0035590; GO:0042118; GO:0042802; GO:0043025; GO:0043195; GO:0043197; GO:0043536; GO:0044297; GO:0045296; GO:0045429; GO:0048266; GO:0048471; GO:0048678; GO:0050850; GO:0050920; GO:0050975; GO:0051897; GO:0051899; GO:0051928; GO:0055117; GO:0055119; GO:0070062; GO:0070588; GO:0071294; GO:0071318; GO:0097190; GO:0099604; GO:1904141; GO:2001028 1999 XR_006392616.1 11 0 0 28 4 NA NA NA NA NA NA 2000 XM_029328307.2 12 51 36 36 105 Q6L8S8 1.19e-59 Beta-1,4-N-acetylgalactosaminyltransferase 3 (Beta4GalNAc-T3) (Beta4GalNAcT3) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase III) (N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 2) (NGalNAc-T2) Mus musculus (Mouse) chondroitin sulfate biosynthetic process [GO:0030206] GO:0005794; GO:0008376; GO:0030206; GO:0032580; GO:0033842; GO:0043231; GO:0047238 2001 XM_044311182.1 174 78 63 86 134 Q62086 1.41e-24 Serum paraoxonase/arylesterase 2 (PON 2) (EC 3.1.1.2) (EC 3.1.1.81) (Aromatic esterase 2) (A-esterase 2) (Serum aryldialkylphosphatase 2) Mus musculus (Mouse) aromatic compound catabolic process [GO:0019439]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636] GO:0004064; GO:0005576; GO:0005634; GO:0005739; GO:0005764; GO:0005886; GO:0006979; GO:0009636; GO:0019439; GO:0042802; GO:0043231; GO:0046872; GO:0102007 2002 XM_044307443.1 19 4 29 5 140 Q58L91 8.13e-39 Venom prothrombin activator oscutarin-C non-catalytic subunit (vPA) (Venom coagulation factor Va-like protein) [Cleaved into: Oscutarin-C non-catalytic subunit heavy chain; Oscutarin-C non-catalytic subunit light chain] Oxyuranus scutellatus (Coastal taipan) envenomation resulting in positive regulation of blood coagulation in another organism [GO:0044469]; positive regulation of blood coagulation in another organism [GO:0035807]; positive regulation of peptidase activity [GO:0010952] GO:0005507; GO:0005576; GO:0010952; GO:0016504; GO:0032991; GO:0035807; GO:0044469; GO:0090729 2003 XM_044307443.1 19 4 29 5 140 Q58L91 1.15e-25 Venom prothrombin activator oscutarin-C non-catalytic subunit (vPA) (Venom coagulation factor Va-like protein) [Cleaved into: Oscutarin-C non-catalytic subunit heavy chain; Oscutarin-C non-catalytic subunit light chain] Oxyuranus scutellatus (Coastal taipan) envenomation resulting in positive regulation of blood coagulation in another organism [GO:0044469]; positive regulation of blood coagulation in another organism [GO:0035807]; positive regulation of peptidase activity [GO:0010952] GO:0005507; GO:0005576; GO:0010952; GO:0016504; GO:0032991; GO:0035807; GO:0044469; GO:0090729 2004 XM_029348943.2 335 292 0 3 0 O54852 5.02e-102 Potassium voltage-gated channel subfamily H member 7 (Ether-a-go-go-related gene potassium channel 3) (ERG-3) (Eag-related protein 3) (Ether-a-go-go-related protein 3) (Voltage-gated potassium channel subunit Kv11.3) Rattus norvegicus (Rat) circadian rhythm [GO:0007623]; membrane repolarization during action potential [GO:0086011]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391] GO:0005242; GO:0005249; GO:0005267; GO:0005886; GO:0006813; GO:0007623; GO:0034765; GO:0042391; GO:0044877; GO:0071805; GO:0086011 2005 XR_006393326.1 0 0 0 11 0 NA NA NA NA NA NA 2006 XM_044324997.1 21 0 21 14 12 NA NA NA NA NA NA 2007 XM_044329134.1 241 174 187 265 298 Q6PCN7 9.3e-180 Helicase-like transcription factor (EC 2.3.2.27) (EC 3.6.4.-) (P113) (RING-type E3 ubiquitin transferase HLTF) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) Mus musculus (Mouse) DNA repair [GO:0006281]; mRNA transcription by RNA polymerase II [GO:0042789]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of neurogenesis [GO:0050767] GO:0003677; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0006281; GO:0008094; GO:0008270; GO:0016363; GO:0016818; GO:0031625; GO:0042789; GO:0045944; GO:0050767; GO:0061630; GO:0090575; GO:0140658 2008 XM_044329134.1 241 174 187 265 298 Q6PCN7 6.31e-26 Helicase-like transcription factor (EC 2.3.2.27) (EC 3.6.4.-) (P113) (RING-type E3 ubiquitin transferase HLTF) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) Mus musculus (Mouse) DNA repair [GO:0006281]; mRNA transcription by RNA polymerase II [GO:0042789]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of neurogenesis [GO:0050767] GO:0003677; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0006281; GO:0008094; GO:0008270; GO:0016363; GO:0016818; GO:0031625; GO:0042789; GO:0045944; GO:0050767; GO:0061630; GO:0090575; GO:0140658 2009 XM_044319727.1 361 0 183 274 183 Q9VS29 3.3e-28 Cell adhesion molecule Dscam2 (Down syndrome cell adhesion molecule-like protein Dscam2) Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; dendrite self-avoidance [GO:0070593]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron projection morphogenesis [GO:0048812] GO:0005886; GO:0007156; GO:0007411; GO:0030424; GO:0042802; GO:0048812; GO:0070593; GO:0098632 2010 XM_044319727.1 361 0 183 274 183 Q9VS29 6.64e-21 Cell adhesion molecule Dscam2 (Down syndrome cell adhesion molecule-like protein Dscam2) Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; dendrite self-avoidance [GO:0070593]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron projection morphogenesis [GO:0048812] GO:0005886; GO:0007156; GO:0007411; GO:0030424; GO:0042802; GO:0048812; GO:0070593; GO:0098632 2011 XM_029348911.2 0 0 100 27 0 NA NA NA NA NA NA 2012 XM_044314491.1 395 536 932 264 74 Q5AXT5 1.35e-31 ATP-dependent DNA helicase PIF1 (EC 3.6.4.12) (DNA repair and recombination helicase PIF1) Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; mitochondrial genome maintenance [GO:0000002]; telomere maintenance [GO:0000723] GO:0000002; GO:0000723; GO:0003677; GO:0005524; GO:0005634; GO:0005657; GO:0005739; GO:0006260; GO:0006281; GO:0006310; GO:0016887; GO:0032508; GO:0043139 2013 XM_029330119.2 1197 1012 1006 1029 1080 NA NA NA NA NA NA 2014 XM_044308732.1 267 158 268 383 311 Q8R2R5 1.06e-29 Leucine-rich repeat-containing protein 61 Mus musculus (Mouse) NA GO:0005737; GO:0005829 2015 XM_044311411.1 0 0 0 0 17 O60290 1.55e-21 Zinc finger protein 862 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006355; GO:0046872; GO:0046983 2016 XM_044313125.1 239 166 106 99 215 Q5EA10 3.92e-131 GPI mannosyltransferase 1 (EC 2.4.1.-) (GPI mannosyltransferase I) (GPI-MT-I) (Phosphatidylinositol-glycan biosynthesis class M protein) (PIG-M) Bos taurus (Bovine) GPI anchor biosynthetic process [GO:0006506] GO:0000030; GO:0004376; GO:0005789; GO:0006506; GO:0051751; GO:1990529 2017 XM_044327327.1 2 600 146 7 62 NA NA NA NA NA NA 2018 XM_029354353.2 11 11 29 35 4 NA NA NA NA NA NA 2019 XM_029342518.2 339 94 110 293 325 Q3UHC7 2.5e-139 Disabled homolog 2-interacting protein (DAB2-interacting protein) (ASK-interacting protein 1) (DOC-2/DAB-2 interactive protein) Mus musculus (Mouse) angiogenesis [GO:0001525]; cell cycle [GO:0007049]; cell motility involved in cerebral cortex radial glia guided migration [GO:0021814]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; I-kappaB phosphorylation [GO:0007252]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; layer formation in cerebral cortex [GO:0021819]; negative regulation of angiogenesis [GO:0016525]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of G0 to G1 transition [GO:0070317]; negative regulation of GTPase activity [GO:0034260]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of phosphatidylinositol 3-kinase activity [GO:0043553]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of Ras protein signal transduction [GO:0046580]; negative regulation of toll-like receptor 4 signaling pathway [GO:0034144]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; negative regulation of vascular endothelial growth factor signaling pathway [GO:1900747]; neuron projection morphogenesis [GO:0048812]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of dendrite development [GO:1900006]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron migration [GO:2001224]; positive regulation of neuron projection development [GO:0010976]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of protein-containing complex assembly [GO:0031334]; positive regulation of synapse maturation [GO:0090129]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein catabolic process [GO:0030163]; regulation of cell cycle [GO:0051726]; regulation of GTPase activity [GO:0043087]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of p38MAPK cascade [GO:1900744]; regulation of protein-containing complex assembly [GO:0043254]; response to unfolded protein [GO:0006986]; tube formation [GO:0035148]; vascular endothelial growth factor receptor-2 signaling pathway [GO:0036324] GO:0000122; GO:0001525; GO:0001933; GO:0005096; GO:0005123; GO:0005737; GO:0005886; GO:0006954; GO:0006986; GO:0007049; GO:0007252; GO:0008285; GO:0008625; GO:0010596; GO:0010633; GO:0010719; GO:0010976; GO:0014067; GO:0016525; GO:0017124; GO:0019900; GO:0019901; GO:0021814; GO:0021819; GO:0030139; GO:0030163; GO:0030308; GO:0030424; GO:0030425; GO:0030948; GO:0031334; GO:0031434; GO:0031435; GO:0032088; GO:0032266; GO:0032809; GO:0034144; GO:0034260; GO:0035148; GO:0035591; GO:0035924; GO:0036312; GO:0036324; GO:0042059; GO:0042177; GO:0042802; GO:0042803; GO:0043025; GO:0043065; GO:0043087; GO:0043122; GO:0043124; GO:0043184; GO:0043254; GO:0043407; GO:0043410; GO:0043507; GO:0043539; GO:0043548; GO:0043553; GO:0044300; GO:0044301; GO:0044877; GO:0045087; GO:0045732; GO:0045892; GO:0045944; GO:0046330; GO:0046580; GO:0047485; GO:0048147; GO:0048812; GO:0050679; GO:0050680; GO:0051721; GO:0051726; GO:0070059; GO:0070273; GO:0070317; GO:0070373; GO:0071222; GO:0071347; GO:0071356; GO:0071364; GO:0071889; GO:0071901; GO:0071902; GO:0090090; GO:0090129; GO:1900006; GO:1900744; GO:1900747; GO:1901800; GO:1990032; GO:1990597; GO:2001224; GO:2001235 2020 XM_044315612.1 7 0 1 0 0 NA NA NA NA NA NA 2021 XM_029333890.2 1210 857 863 755 731 Q8GW29 2.99e-52 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG7 (EC 3.2.2.n1) (Protein LONELY GUY 7) Arabidopsis thaliana (Mouse-ear cress) cytokinin biosynthetic process [GO:0009691] GO:0005634; GO:0005829; GO:0009691; GO:0016799; GO:0102682 2022 XM_029345916.2 247 117 259 143 186 Q54TR1 6.82e-86 Counting factor associated protein D Dictyostelium discoideum (Social amoeba) immune response [GO:0006955]; negative regulation of asexual reproduction [GO:1903665]; positive regulation of chemorepellent activity [GO:1903669]; protein localization to plasma membrane [GO:0072659]; proteolysis involved in protein catabolic process [GO:0051603]; sorocarp morphogenesis [GO:0031288] GO:0004197; GO:0005576; GO:0005615; GO:0005764; GO:0006955; GO:0031288; GO:0031410; GO:0051603; GO:0072659; GO:1903665; GO:1903669 2023 XM_044329190.1 0 13 3 0 3 NA NA NA NA NA NA 2024 XM_044326523.1 11 16 0 1 10 NA NA NA NA NA NA 2025 XM_029348705.2 373 344 308 328 408 Q8N9F7 3.14e-111 Lysophospholipase D GDPD1 (EC 3.1.4.-) (Glycerophosphodiester phosphodiesterase 4) (Glycerophosphodiester phosphodiesterase domain-containing protein 1) Homo sapiens (Human) glycerophospholipid catabolic process [GO:0046475]; N-acylethanolamine metabolic process [GO:0070291] GO:0004622; GO:0005783; GO:0005789; GO:0008081; GO:0016020; GO:0046475; GO:0046872; GO:0048471; GO:0070291 2026 XM_044326790.1 7 7 2 1 4 NA NA NA NA NA NA 2027 XM_044320960.1 63 322 281 306 389 NA NA NA NA NA NA 2028 XM_044322088.1 1365 583 790 1329 1039 NA NA NA NA NA NA 2029 XM_044324027.1 5 0 6 0 42 NA NA NA NA NA NA 2030 XM_044318371.1 52 7 1 8 49 NA NA NA NA NA NA 2031 XM_044328552.1 53 41 22 76 100 NA NA NA NA NA NA 2032 XM_029335366.2 79 59 38 128 118 P11275 5.06e-62 Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II subunit alpha) (CaMK-II subunit alpha) (EC 2.7.11.17) Rattus norvegicus (Rat) angiotensin-activated signaling pathway [GO:0038166]; calcium ion transport [GO:0006816]; calmodulin dependent kinase signaling pathway [GO:0099004]; cellular response to interferon-beta [GO:0035458]; dendrite morphogenesis [GO:0048813]; dendritic spine development [GO:0060996]; G1/S transition of mitotic cell cycle [GO:0000082]; ionotropic glutamate receptor signaling pathway [GO:0035235]; negative regulation of hydrolase activity [GO:0051346]; NMDA selective glutamate receptor signaling pathway [GO:0098989]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine autophosphorylation [GO:1990443]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of endocannabinoid signaling pathway [GO:2000124]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of neuron migration [GO:2001222]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of neurotransmitter secretion [GO:0046928]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of synaptic vesicle docking [GO:0099148]; response to ischemia [GO:0002931] GO:0000082; GO:0002931; GO:0004674; GO:0004683; GO:0005516; GO:0005524; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0005954; GO:0006468; GO:0006816; GO:0009931; GO:0010666; GO:0014069; GO:0016020; GO:0016301; GO:0018105; GO:0030424; GO:0030425; GO:0032794; GO:0032839; GO:0035235; GO:0035254; GO:0035458; GO:0038166; GO:0042802; GO:0042803; GO:0043005; GO:0043025; GO:0043197; GO:0045202; GO:0046427; GO:0046777; GO:0046872; GO:0046928; GO:0048168; GO:0048813; GO:0051092; GO:0051346; GO:0051928; GO:0060996; GO:0098685; GO:0098696; GO:0098970; GO:0098978; GO:0098989; GO:0099004; GO:0099148; GO:0099523; GO:0099524; GO:0099573; GO:0099634; GO:0106310; GO:1902108; GO:1903076; GO:1990443; GO:2000124; GO:2001222 2033 XM_029339357.2 1678 1691 908 1542 1108 NA NA NA NA NA NA 2034 XM_044327240.1 236 95 131 215 71 NA NA NA NA NA NA 2035 XM_044321622.1 11 33 27 3 39 NA NA NA NA NA NA 2036 XM_029346846.2 11 9 13 21 7 NA NA NA NA NA NA 2037 XM_044312289.1 0 0 158 0 0 Q9U6Y6 2.14e-110 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 2038 XR_006394794.1 21 0 0 0 6 NA NA NA NA NA NA 2039 XM_044315176.1 659 877 873 1201 650 P97321 1.67e-70 Prolyl endopeptidase FAP (EC 3.4.21.26) (Dipeptidyl peptidase FAP) (EC 3.4.14.5) (Fibroblast activation protein alpha) (FAPalpha) (Gelatine degradation protease FAP) (EC 3.4.21.-) (Integral membrane serine protease) (Post-proline cleaving enzyme) (Serine integral membrane protease) (SIMP) (Surface-expressed protease) (Seprase) [Cleaved into: Antiplasmin-cleaving enzyme FAP, soluble form (APCE) (EC 3.4.14.5) (EC 3.4.21.-) (EC 3.4.21.26)] Mus musculus (Mouse) angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; melanocyte apoptotic process [GO:1902362]; melanocyte proliferation [GO:0097325]; negative regulation of cell proliferation involved in contact inhibition [GO:0060244]; negative regulation of extracellular matrix disassembly [GO:0010716]; negative regulation of extracellular matrix organization [GO:1903054]; positive regulation of execution phase of apoptosis [GO:1900119]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of cell cycle [GO:0051726]; regulation of collagen catabolic process [GO:0010710] GO:0001525; GO:0002020; GO:0004175; GO:0004252; GO:0005178; GO:0005615; GO:0005886; GO:0006508; GO:0007155; GO:0008233; GO:0008236; GO:0008239; GO:0009986; GO:0010710; GO:0010716; GO:0030027; GO:0031258; GO:0032587; GO:0042802; GO:0042803; GO:0043542; GO:0045177; GO:0045178; GO:0051603; GO:0051726; GO:0060244; GO:0070161; GO:0097325; GO:1900119; GO:1902362; GO:1903054; GO:1905368 2040 XM_029333780.2 239 0 186 0 17 Q7TN88 2.91e-68 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 2041 XM_029333780.2 239 0 186 0 17 Q7TN88 2.89e-49 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 2042 XM_029333800.2 211 104 219 198 389 H9JW43 1.11e-67 Chitin deacetylase 8 (BmCDA8) (EC 3.5.1.41) (Chitin deacetylase 17) Bombyx mori (Silk moth) chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272] GO:0000272; GO:0004099; GO:0005615; GO:0006032; GO:0008270 2043 XM_029345496.2 32 142 74 60 30 P54357 3.82e-50 Myosin-2 essential light chain (Myosin II essential light chain) (Non-muscle myosin essential light chain) Drosophila melanogaster (Fruit fly) actin filament-based movement [GO:0030048] GO:0005509; GO:0005829; GO:0016460; GO:0017022; GO:0030048; GO:0031475; GO:0031476; GO:0031477; GO:0032036 2044 XM_029341329.2 1563 702 610 1305 1144 Q99NB1 0 Acetyl-coenzyme A synthetase 2-like, mitochondrial (EC 6.2.1.1) (Acetate--CoA ligase 2) (Acetyl-CoA synthetase 2) (AceCS2) (Acyl-CoA synthetase short-chain family member 1) (Propionate--CoA ligase) (EC 6.2.1.17) Mus musculus (Mouse) acetate biosynthetic process [GO:0019413]; acetyl-CoA biosynthetic process [GO:0006085]; acetyl-CoA biosynthetic process from acetate [GO:0019427]; propionate biosynthetic process [GO:0019542] GO:0003987; GO:0005524; GO:0005739; GO:0005759; GO:0006085; GO:0016208; GO:0019413; GO:0019427; GO:0019542; GO:0050218 2045 XM_029340994.2 258 290 150 322 282 O75752 1.28e-25 UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1 (Beta-1,3-GalNAc-T1) (EC 2.4.1.79) (Beta-1,3-galactosyltransferase 3) (Beta-1,3-GalTase 3) (Beta3Gal-T3) (Beta3GalT3) (b3Gal-T3) (Beta-3-Gx-T3) (Galactosylgalactosylglucosylceramide beta-D-acetyl-galactosaminyltransferase) (Globoside synthase) (UDP-N-acetylgalactosamine:globotriaosylceramide beta-1,3-N-acetylgalactosaminyltransferase) Homo sapiens (Human) glycosphingolipid metabolic process [GO:0006687]; oligosaccharide biosynthetic process [GO:0009312]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0006687; GO:0008194; GO:0008499; GO:0009312; GO:0016757; GO:0047273 2046 XM_029345752.2 1192 390 507 1283 744 Q91035 9.39e-94 Sonic hedgehog protein (SHH) (EC 3.1.-.-) (Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains) (ShhNC) [Cleaved into: Sonic hedgehog protein N-product (ShhN) (Shh N-terminal processed signaling domains) (ShhNp)] Gallus gallus (Chicken) anterior/posterior pattern specification [GO:0009952]; apoptotic signaling pathway [GO:0097190]; cell fate determination [GO:0001709]; cell fate specification involved in pattern specification [GO:0060573]; cell-cell signaling [GO:0007267]; chondroblast differentiation [GO:0060591]; commissural neuron axon guidance [GO:0071679]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; fibroblast growth factor production [GO:0090269]; floor plate formation [GO:0021508]; growth plate cartilage chondrocyte growth [GO:0003430]; homeostasis of number of retina cells [GO:0048877]; intein-mediated protein splicing [GO:0016539]; negative regulation of apoptotic process [GO:0043066]; negative regulation of BMP signaling pathway [GO:0030514]; optic cup formation involved in camera-type eye development [GO:0003408]; optic nerve morphogenesis [GO:0021631]; polarity specification of anterior/posterior axis [GO:0009949]; polarity specification of dorsal/ventral axis [GO:0009951]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of cell morphogenesis involved in differentiation [GO:0010770]; positive regulation of gene expression [GO:0010628]; positive regulation of neural retina development [GO:0061075]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of smoothened signaling pathway [GO:0045880]; protein autoprocessing [GO:0016540]; proteoglycan biosynthetic process [GO:0030166]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; regulation of cell differentiation involved in tissue homeostasis [GO:0060786]; regulation of gene expression [GO:0010468]; regulation of neural precursor cell proliferation [GO:2000177]; response to retinoic acid [GO:0032526]; retina homeostasis [GO:0001895]; retinal pigment epithelium development [GO:0003406]; self proteolysis [GO:0097264]; signaling [GO:0023052]; spinal cord dorsal/ventral patterning [GO:0021513]; tissue development [GO:0009888] GO:0000139; GO:0001709; GO:0001895; GO:0003406; GO:0003408; GO:0003430; GO:0005509; GO:0005576; GO:0005615; GO:0005783; GO:0005789; GO:0005794; GO:0005886; GO:0007267; GO:0008233; GO:0008270; GO:0009880; GO:0009888; GO:0009949; GO:0009951; GO:0009952; GO:0010468; GO:0010628; GO:0010694; GO:0010770; GO:0016015; GO:0016539; GO:0016540; GO:0021508; GO:0021513; GO:0021631; GO:0023052; GO:0030166; GO:0030326; GO:0030514; GO:0032526; GO:0042733; GO:0043066; GO:0045669; GO:0045880; GO:0048877; GO:0060059; GO:0060573; GO:0060591; GO:0060785; GO:0060786; GO:0061075; GO:0071679; GO:0090269; GO:0097190; GO:0097264; GO:0140853; GO:2000177 2047 XM_029351041.2 596 380 48 984 378 NA NA NA NA NA NA 2048 XR_006396464.1 0 0 40 6 0 Q99570 3.64e-23 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 2049 XM_044312580.1 38 47 68 6 43 NA NA NA NA NA NA 2050 XM_044320425.1 89 181 21 74 19 NA NA NA NA NA NA 2051 XM_044312542.1 0 1 2 3 9 Q96AY4 7.34e-57 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2052 XM_044312542.1 0 1 2 3 9 Q96AY4 1.45e-52 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2053 XM_044312542.1 0 1 2 3 9 Q96AY4 3.96e-50 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2054 XM_044312542.1 0 1 2 3 9 Q96AY4 2.18e-49 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2055 XM_044312542.1 0 1 2 3 9 Q96AY4 1.79e-48 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2056 XM_044312542.1 0 1 2 3 9 Q96AY4 3.24e-47 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2057 XM_044312542.1 0 1 2 3 9 Q96AY4 5.19e-47 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2058 XM_044312542.1 0 1 2 3 9 Q96AY4 8.94e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2059 XM_044312542.1 0 1 2 3 9 Q96AY4 9.77e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2060 XM_044312542.1 0 1 2 3 9 Q96AY4 1.05e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2061 XM_044312542.1 0 1 2 3 9 Q96AY4 2.76e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2062 XM_044312542.1 0 1 2 3 9 Q96AY4 1.48e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2063 XM_044312542.1 0 1 2 3 9 Q96AY4 1.76e-37 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2064 XM_044312542.1 0 1 2 3 9 Q96AY4 5.53e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2065 XM_044312542.1 0 1 2 3 9 Q96AY4 1.42e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2066 XM_044312542.1 0 1 2 3 9 Q96AY4 3.63e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2067 XM_044312542.1 0 1 2 3 9 Q96AY4 1.39e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2068 XM_029339399.2 886 363 214 656 451 Q66GS9 0 Centrosomal protein of 135 kDa (Cep135) (Centrosomal protein 4) Homo sapiens (Human) centriole replication [GO:0007099]; centriole-centriole cohesion [GO:0010457]; positive regulation of establishment of protein localization [GO:1904951]; positive regulation of non-motile cilium assembly [GO:1902857] GO:0005813; GO:0005814; GO:0005829; GO:0007099; GO:0008022; GO:0010457; GO:1902857; GO:1904951 2069 XM_044307714.1 0 97 1 0 0 NA NA NA NA NA NA 2070 XM_044311458.1 6 0 102 19 93 NA NA NA NA NA NA 2071 XM_044312235.1 32 7 52 58 86 NA NA NA NA NA NA 2072 XM_044324280.1 34 0 0 10 19 Q8NB15 1.93e-43 Zinc finger protein 511 Homo sapiens (Human) NA GO:0003677; GO:0005634; GO:0046872 2073 XM_044329057.1 569 426 270 400 369 P52429 9.84e-162 Diacylglycerol kinase epsilon (DAG kinase epsilon) (EC 2.7.1.107) (Diglyceride kinase epsilon) (DGK-epsilon) Homo sapiens (Human) diacylglycerol metabolic process [GO:0046339]; intracellular signal transduction [GO:0035556]; lipid phosphorylation [GO:0046834]; modulation of chemical synaptic transmission [GO:0050804]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidylinositol biosynthetic process [GO:0006661]; platelet activation [GO:0030168]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205] GO:0004143; GO:0005524; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0006654; GO:0006661; GO:0007205; GO:0016020; GO:0016301; GO:0030168; GO:0035556; GO:0046339; GO:0046834; GO:0046872; GO:0050804; GO:0098978 2074 XM_029339946.2 18228 23428 10816 17302 13046 P05386 2.86e-22 60S acidic ribosomal protein P1 (Large ribosomal subunit protein P1) Homo sapiens (Human) cytoplasmic translation [GO:0002181]; translation [GO:0006412]; translational elongation [GO:0006414] GO:0002181; GO:0003735; GO:0005737; GO:0005829; GO:0005925; GO:0006412; GO:0006414; GO:0022625; GO:0022626; GO:0030295; GO:0043021 2075 XR_006392692.1 0 0 0 59 0 NA NA NA NA NA NA 2076 XM_029347541.2 215 63 70 196 260 NA NA NA NA NA NA 2077 XR_006394263.1 11 4 43 9 189 NA NA NA NA NA NA 2078 XM_029346910.2 577 345 269 373 388 P98069 6.05e-29 Bone morphogenetic protein 1 homolog (EC 3.4.24.-) (SUBMP) Strongylocentrotus purpuratus (Purple sea urchin) dorsal/ventral pattern formation [GO:0009953]; protein processing [GO:0016485] GO:0004222; GO:0005509; GO:0005615; GO:0008270; GO:0009953; GO:0016485 2079 XR_003823357.2 97 156 293 253 368 NA NA NA NA NA NA 2080 XM_029338446.2 4175 3486 2382 3581 4365 Q2THW0 5.23e-92 Palmitoyltransferase ZDHHC5-A (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 5-A) (DHHC-5A) Danio rerio (Zebrafish) (Brachydanio rerio) protein palmitoylation [GO:0018345] GO:0005886; GO:0016409; GO:0018345; GO:0019706 2081 XM_029331829.2 21385 68179 26334 15051 13284 P23358 2.91e-93 60S ribosomal protein L12 Rattus norvegicus (Rat) positive regulation of translational elongation [GO:0045901]; translation [GO:0006412] GO:0003735; GO:0005634; GO:0005730; GO:0005737; GO:0006412; GO:0014069; GO:0015934; GO:0022625; GO:0022626; GO:0045202; GO:0045901; GO:0070180 2082 XR_006396144.1 591 817 431 1048 1198 NA NA NA NA NA NA 2083 XR_003824057.2 6 8 4 7 32 NA NA NA NA NA NA 2084 XM_044308883.1 0 32 27 2 5 P07949 4.68e-26 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; axon guidance [GO:0007411]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; lymphocyte migration into lymphoid organs [GO:0097021]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; posterior midgut development [GO:0007497]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006468; GO:0006919; GO:0007156; GO:0007158; GO:0007165; GO:0007169; GO:0007411; GO:0007497; GO:0009410; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0038023; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0097021; GO:0098797; GO:2001241 2085 XM_029352796.2 16 1 10 5 8 NA NA NA NA NA NA 2086 XR_006393450.1 27 4 10 32 1 NA NA NA NA NA NA 2087 XR_003827591.2 72 177 170 331 84 NA NA NA NA NA NA 2088 XM_044322216.1 168 115 116 95 294 NA NA NA NA NA NA 2089 XM_029335152.2 5540 3866 2844 3235 4876 NA NA NA NA NA NA 2090 XM_029326752.2 228 115 127 173 153 NA NA NA NA NA NA 2091 XM_044321934.1 0 0 4 1 65 NA NA NA NA NA NA 2092 XM_044327889.1 20 9 6 13 67 P08953 1.71e-47 Protein toll Drosophila melanogaster (Fruit fly) antifungal innate immune response [GO:0061760]; cell adhesion [GO:0007155]; cell competition in a multicellular organism [GO:0035212]; defense response to Gram-positive bacterium [GO:0050830]; defense response to oomycetes [GO:0002229]; detection of virus [GO:0009597]; dorsal/ventral axis specification [GO:0009950]; heart development [GO:0007507]; innate immune response [GO:0045087]; larval somatic muscle development [GO:0007526]; negative regulation of cell growth [GO:0030308]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of multicellular organism growth [GO:0040015]; positive regulation of antifungal peptide production [GO:0002804]; positive regulation of antimicrobial peptide production [GO:0002225]; positive regulation of hemocyte proliferation [GO:0035208]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of embryonic pattern specification [GO:1902875]; response to tumor cell [GO:0002347]; response to wounding [GO:0009611]; synapse assembly [GO:0007416]; synaptic target inhibition [GO:0016201]; Toll signaling pathway [GO:0008063]; toll-like receptor signaling pathway [GO:0002224] GO:0002224; GO:0002225; GO:0002229; GO:0002347; GO:0002804; GO:0004888; GO:0004896; GO:0005769; GO:0005886; GO:0007155; GO:0007416; GO:0007507; GO:0007526; GO:0008063; GO:0009597; GO:0009611; GO:0009897; GO:0009950; GO:0009986; GO:0016201; GO:0019955; GO:0030308; GO:0032154; GO:0035208; GO:0035212; GO:0038023; GO:0040015; GO:0042802; GO:0045087; GO:0045944; GO:0046627; GO:0046790; GO:0050135; GO:0050830; GO:0061760; GO:0061809; GO:0070976; GO:1902875 2093 XM_029351710.2 1043 545 393 992 1182 Q9BUZ4 7.7e-70 TNF receptor-associated factor 4 (EC 2.3.2.27) (Cysteine-rich domain associated with RING and Traf domains protein 1) (Metastatic lymph node gene 62 protein) (MLN 62) (RING finger protein 83) Homo sapiens (Human) activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; innate immune response [GO:0045087]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein kinase activity [GO:0045860]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; respiratory gaseous exchange by respiratory system [GO:0007585]; respiratory tube development [GO:0030323] GO:0001650; GO:0005164; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0005923; GO:0006915; GO:0007250; GO:0007585; GO:0008270; GO:0016740; GO:0019901; GO:0030323; GO:0031625; GO:0031996; GO:0042802; GO:0042981; GO:0043122; GO:0043161; GO:0045087; GO:0045860; GO:0046330; GO:0048471; GO:0050699 2094 XM_044324702.1 79 167 25 74 125 NA NA NA NA NA NA 2095 XM_044313439.1 22 9 5 0 0 NA NA NA NA NA NA 2096 XR_006398202.1 153 52 44 103 45 Q21279 5.3e-83 Probable tubulin polyglutamylase ttll-15 (EC 6.-.-.-) (Tubulin--tyrosine ligase-like protein 15) Caenorhabditis elegans oviposition [GO:0018991]; protein modification process [GO:0036211] GO:0005524; GO:0016874; GO:0018991; GO:0036211 2097 XM_029357635.2 1200 498 546 864 927 NA NA NA NA NA NA 2098 XM_044311006.1 0 0 2 0 9 NA NA NA NA NA NA 2099 XM_044318315.1 1087 749 445 702 541 Q7PWV1 3.84e-47 Aquaporin AQPAn.G Anopheles gambiae (African malaria mosquito) water transport [GO:0006833] GO:0005886; GO:0006833; GO:0015250; GO:0016020 2100 XM_044318315.1 1087 749 445 702 541 Q7PWV1 8.1e-38 Aquaporin AQPAn.G Anopheles gambiae (African malaria mosquito) water transport [GO:0006833] GO:0005886; GO:0006833; GO:0015250; GO:0016020 2101 XM_029357831.2 0 0 0 7 0 Q7TT47 0 Paraplegin (EC 3.4.24.-) Rattus norvegicus (Rat) anterograde axonal transport [GO:0008089]; integrin-mediated signaling pathway [GO:0007229]; mitochondrial outer membrane permeabilization involved in programmed cell death [GO:1902686]; mitochondrial protein processing [GO:0034982]; mitochondrion organization [GO:0007005]; positive regulation of cell-matrix adhesion [GO:0001954]; regulation of mitochondrial membrane permeability [GO:0046902] GO:0001954; GO:0004176; GO:0004222; GO:0005524; GO:0005739; GO:0005743; GO:0005745; GO:0005757; GO:0007005; GO:0007229; GO:0008089; GO:0008270; GO:0016887; GO:0034982; GO:0046902; GO:1902686; GO:1904115 2102 XM_029357866.2 7739 6395 4449 8952 10420 P00125 1.68e-113 Cytochrome c1, heme protein, mitochondrial (EC 7.1.1.8) (Complex III subunit 4) (Complex III subunit IV) (Cytochrome b-c1 complex subunit 4) (Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit) (Cytochrome c-1) Bos taurus (Bovine) mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122] GO:0005739; GO:0005743; GO:0005750; GO:0006122; GO:0008121; GO:0020037; GO:0046872 2103 XM_029351869.2 0 0 3 10 92 NA NA NA NA NA NA 2104 XR_006392934.1 41 2 25 5 151 NA NA NA NA NA NA 2105 XM_044321129.1 256 190 173 445 526 P22105 1.76e-49 Tenascin-X (TN-X) (Hexabrachion-like protein) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; elastic fiber assembly [GO:0048251]; extracellular matrix organization [GO:0030198]; fatty acid metabolic process [GO:0006631]; positive regulation of cell fate determination [GO:1905935]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen fibril organization [GO:1904028]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of transforming growth factor beta activation [GO:1901390]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of cell migration [GO:0030334]; regulation of JUN kinase activity [GO:0043506]; triglyceride metabolic process [GO:0006641] GO:0005178; GO:0005201; GO:0005518; GO:0005576; GO:0005615; GO:0006631; GO:0006641; GO:0007155; GO:0007160; GO:0008201; GO:0008284; GO:0010718; GO:0010862; GO:0030036; GO:0030155; GO:0030198; GO:0030199; GO:0030334; GO:0030511; GO:0031012; GO:0032963; GO:0043506; GO:0045595; GO:0048251; GO:0062023; GO:0070062; GO:0090733; GO:0098609; GO:0098633; GO:1900748; GO:1901390; GO:1904028; GO:1905935 2106 XM_044321129.1 256 190 173 445 526 P22105 2.5e-49 Tenascin-X (TN-X) (Hexabrachion-like protein) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; elastic fiber assembly [GO:0048251]; extracellular matrix organization [GO:0030198]; fatty acid metabolic process [GO:0006631]; positive regulation of cell fate determination [GO:1905935]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen fibril organization [GO:1904028]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of transforming growth factor beta activation [GO:1901390]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of cell migration [GO:0030334]; regulation of JUN kinase activity [GO:0043506]; triglyceride metabolic process [GO:0006641] GO:0005178; GO:0005201; GO:0005518; GO:0005576; GO:0005615; GO:0006631; GO:0006641; GO:0007155; GO:0007160; GO:0008201; GO:0008284; GO:0010718; GO:0010862; GO:0030036; GO:0030155; GO:0030198; GO:0030199; GO:0030334; GO:0030511; GO:0031012; GO:0032963; GO:0043506; GO:0045595; GO:0048251; GO:0062023; GO:0070062; GO:0090733; GO:0098609; GO:0098633; GO:1900748; GO:1901390; GO:1904028; GO:1905935 2107 XM_044321129.1 256 190 173 445 526 P22105 4.45e-49 Tenascin-X (TN-X) (Hexabrachion-like protein) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; elastic fiber assembly [GO:0048251]; extracellular matrix organization [GO:0030198]; fatty acid metabolic process [GO:0006631]; positive regulation of cell fate determination [GO:1905935]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen fibril organization [GO:1904028]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of transforming growth factor beta activation [GO:1901390]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of cell migration [GO:0030334]; regulation of JUN kinase activity [GO:0043506]; triglyceride metabolic process [GO:0006641] GO:0005178; GO:0005201; GO:0005518; GO:0005576; GO:0005615; GO:0006631; GO:0006641; GO:0007155; GO:0007160; GO:0008201; GO:0008284; GO:0010718; GO:0010862; GO:0030036; GO:0030155; GO:0030198; GO:0030199; GO:0030334; GO:0030511; GO:0031012; GO:0032963; GO:0043506; GO:0045595; GO:0048251; GO:0062023; GO:0070062; GO:0090733; GO:0098609; GO:0098633; GO:1900748; GO:1901390; GO:1904028; GO:1905935 2108 XM_044321129.1 256 190 173 445 526 P22105 2.59e-48 Tenascin-X (TN-X) (Hexabrachion-like protein) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; elastic fiber assembly [GO:0048251]; extracellular matrix organization [GO:0030198]; fatty acid metabolic process [GO:0006631]; positive regulation of cell fate determination [GO:1905935]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen fibril organization [GO:1904028]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of transforming growth factor beta activation [GO:1901390]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of cell migration [GO:0030334]; regulation of JUN kinase activity [GO:0043506]; triglyceride metabolic process [GO:0006641] GO:0005178; GO:0005201; GO:0005518; GO:0005576; GO:0005615; GO:0006631; GO:0006641; GO:0007155; GO:0007160; GO:0008201; GO:0008284; GO:0010718; GO:0010862; GO:0030036; GO:0030155; GO:0030198; GO:0030199; GO:0030334; GO:0030511; GO:0031012; GO:0032963; GO:0043506; GO:0045595; GO:0048251; GO:0062023; GO:0070062; GO:0090733; GO:0098609; GO:0098633; GO:1900748; GO:1901390; GO:1904028; GO:1905935 2109 XM_044321129.1 256 190 173 445 526 P22105 6.4e-34 Tenascin-X (TN-X) (Hexabrachion-like protein) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; elastic fiber assembly [GO:0048251]; extracellular matrix organization [GO:0030198]; fatty acid metabolic process [GO:0006631]; positive regulation of cell fate determination [GO:1905935]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen fibril organization [GO:1904028]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of transforming growth factor beta activation [GO:1901390]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of cell migration [GO:0030334]; regulation of JUN kinase activity [GO:0043506]; triglyceride metabolic process [GO:0006641] GO:0005178; GO:0005201; GO:0005518; GO:0005576; GO:0005615; GO:0006631; GO:0006641; GO:0007155; GO:0007160; GO:0008201; GO:0008284; GO:0010718; GO:0010862; GO:0030036; GO:0030155; GO:0030198; GO:0030199; GO:0030334; GO:0030511; GO:0031012; GO:0032963; GO:0043506; GO:0045595; GO:0048251; GO:0062023; GO:0070062; GO:0090733; GO:0098609; GO:0098633; GO:1900748; GO:1901390; GO:1904028; GO:1905935 2110 XM_044321129.1 256 190 173 445 526 P22105 4.5e-25 Tenascin-X (TN-X) (Hexabrachion-like protein) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; elastic fiber assembly [GO:0048251]; extracellular matrix organization [GO:0030198]; fatty acid metabolic process [GO:0006631]; positive regulation of cell fate determination [GO:1905935]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen fibril organization [GO:1904028]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of transforming growth factor beta activation [GO:1901390]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of cell migration [GO:0030334]; regulation of JUN kinase activity [GO:0043506]; triglyceride metabolic process [GO:0006641] GO:0005178; GO:0005201; GO:0005518; GO:0005576; GO:0005615; GO:0006631; GO:0006641; GO:0007155; GO:0007160; GO:0008201; GO:0008284; GO:0010718; GO:0010862; GO:0030036; GO:0030155; GO:0030198; GO:0030199; GO:0030334; GO:0030511; GO:0031012; GO:0032963; GO:0043506; GO:0045595; GO:0048251; GO:0062023; GO:0070062; GO:0090733; GO:0098609; GO:0098633; GO:1900748; GO:1901390; GO:1904028; GO:1905935 2111 XM_044316835.1 65 61 0 51 0 NA NA NA NA NA NA 2112 XR_006393477.1 60 98 81 83 103 NA NA NA NA NA NA 2113 XM_044315345.1 12 12 0 31 5 NA NA NA NA NA NA 2114 XM_029336902.2 1329 1072 1421 1623 1294 E7F4Z4 6.09e-59 Palmitoyltransferase ZDHHC1 (EC 2.3.1.225) (DHHC domain-containing protein 1) (Zinc finger DHHC domain-containing protein 1) Danio rerio (Zebrafish) (Brachydanio rerio) peptidyl-L-cysteine S-palmitoylation [GO:0018230]; protein targeting to membrane [GO:0006612] GO:0005783; GO:0005789; GO:0005794; GO:0006612; GO:0010008; GO:0018230; GO:0019706 2115 XM_029335690.2 2415 1580 1176 1983 2208 O88664 0 Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1) Rattus norvegicus (Rat) cellular response to DNA damage stimulus [GO:0006974]; central nervous system neuron development [GO:0021954]; DNA repair [GO:0006281]; execution phase of apoptosis [GO:0097194]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; microtubule cytoskeleton organization [GO:0000226]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; negative regulation of microtubule depolymerization [GO:0007026]; neuron cellular homeostasis [GO:0070050]; neuron projection morphogenesis [GO:0048812]; phosphorylation [GO:0016310]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein acetylation [GO:1901985]; positive regulation of stress-activated MAPK cascade [GO:0032874]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cytoskeleton organization [GO:0051493]; regulation of MAPK cascade [GO:0043408]; regulation of microtubule cytoskeleton organization [GO:0070507] GO:0000165; GO:0000226; GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0006281; GO:0006468; GO:0006974; GO:0007026; GO:0007095; GO:0008022; GO:0015630; GO:0016301; GO:0016310; GO:0019901; GO:0021954; GO:0030295; GO:0031489; GO:0032874; GO:0032956; GO:0035556; GO:0043014; GO:0043408; GO:0043539; GO:0046330; GO:0046777; GO:0048471; GO:0048487; GO:0048812; GO:0051493; GO:0070050; GO:0070507; GO:0097194; GO:0106310; GO:1901985 2116 XR_003823011.1 2 1 12 2 23 NA NA NA NA NA NA 2117 XM_029333024.2 969 570 519 1296 872 Q811I0 6.53e-48 ATP synthase mitochondrial F1 complex assembly factor 1 Mus musculus (Mouse) mitochondrial proton-transporting ATP synthase complex assembly [GO:0033615] GO:0005739; GO:0033615 2118 XM_044312938.1 59 36 7 1 8 Q8K3Z0 4.81e-33 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 2119 XM_029355302.2 373 542 407 460 423 Q5RDZ2 2.71e-87 Lambda-crystallin homolog (EC 1.1.1.45) (L-gulonate 3-dehydrogenase) (Gul3DH) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) fatty acid metabolic process [GO:0006631]; glucuronate catabolic process to xylulose 5-phosphate [GO:0019640] GO:0005829; GO:0006631; GO:0019640; GO:0042803; GO:0050104; GO:0070403 2120 XR_006393632.1 8 0 9 15 25 NA NA NA NA NA NA 2121 XM_044324650.1 4 1 21 1 64 B8WI85 1.26e-141 Uncharacterized skeletal organic matrix protein 7 (Uncharacterized SOMP-7) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 2122 XM_044324650.1 4 1 21 1 64 B8WI85 7.02e-115 Uncharacterized skeletal organic matrix protein 7 (Uncharacterized SOMP-7) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 2123 XM_044324650.1 4 1 21 1 64 B8WI85 1.39e-30 Uncharacterized skeletal organic matrix protein 7 (Uncharacterized SOMP-7) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 2124 XM_044316687.1 0 0 5 5 14 NA NA NA NA NA NA 2125 XR_006393899.1 41 2 25 5 151 NA NA NA NA NA NA 2126 XM_029326574.2 0 11 0 8 7 P04323 5.01e-71 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 2127 XM_044325516.1 60 15 49 16 58 NA NA NA NA NA NA 2128 XM_029331773.2 157 0 0 0 178 NA NA NA NA NA NA 2129 XM_029343978.2 0 84 0 0 302 B9EJ86 0 Oxysterol-binding protein-related protein 8 (ORP-8) (OSBP-related protein 8) Mus musculus (Mouse) activation of protein kinase B activity [GO:0032148]; fat cell differentiation [GO:0045444]; negative regulation of cell migration [GO:0030336]; negative regulation of sequestering of triglyceride [GO:0010891]; phospholipid transport [GO:0015914]; positive regulation of glucose import [GO:0046326]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of protein kinase B signaling [GO:0051897]; protein localization to nuclear pore [GO:0090204] GO:0001786; GO:0005783; GO:0005789; GO:0005829; GO:0010891; GO:0015248; GO:0015485; GO:0015914; GO:0016020; GO:0030336; GO:0031965; GO:0032148; GO:0032541; GO:0032934; GO:0043231; GO:0045444; GO:0046326; GO:0046628; GO:0051897; GO:0070273; GO:0090204; GO:0140343 2130 XM_029335950.2 0 0 4 199 0 Q12767 2.78e-139 Transmembrane protein 94 Homo sapiens (Human) NA GO:0016020 2131 XR_006394712.1 42 27 47 23 40 NA NA NA NA NA NA 2132 XM_029337233.2 242 0 13 184 272 NA NA NA NA NA NA 2133 XM_044324367.1 3628 1958 2754 5671 4788 NA NA NA NA NA NA 2134 XM_029324122.2 0 0 13 24 0 NA NA NA NA NA NA 2135 XR_006397494.1 1084 680 466 1075 950 NA NA NA NA NA NA 2136 XM_044318179.1 523 272 386 434 417 Q2TBT5 3.08e-102 Ribonuclease H2 subunit A (RNase H2 subunit A) (EC 3.1.26.4) (Ribonuclease HI large subunit) (RNase HI large subunit) (Ribonuclease HI subunit A) Bos taurus (Bovine) DNA replication, removal of RNA primer [GO:0043137]; mismatch repair [GO:0006298]; RNA catabolic process [GO:0006401] GO:0003723; GO:0004523; GO:0005654; GO:0005829; GO:0006298; GO:0006401; GO:0032299; GO:0043137; GO:0046872 2137 XM_044326564.1 35 23 15 16 37 NA NA NA NA NA NA 2138 XM_044321597.1 292 72 742 118 122 Q80TV8 1.14e-86 CLIP-associating protein 1 (Cytoplasmic linker-associated protein 1) Mus musculus (Mouse) astral microtubule organization [GO:0030953]; cell division [GO:0051301]; cell migration [GO:0016477]; establishment of cell polarity [GO:0030010]; establishment of mitotic spindle localization [GO:0040001]; establishment of spindle orientation [GO:0051294]; exit from mitosis [GO:0010458]; Golgi organization [GO:0007030]; microtubule anchoring [GO:0034453]; microtubule bundle formation [GO:0001578]; microtubule cytoskeleton organization [GO:0000226]; microtubule nucleation [GO:0007020]; microtubule organizing center organization [GO:0031023]; mitotic spindle assembly [GO:0090307]; mitotic spindle organization [GO:0007052]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of microtubule polymerization or depolymerization [GO:0031111]; negative regulation of stress fiber assembly [GO:0051497]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of exocytosis [GO:0045921]; positive regulation of extracellular matrix disassembly [GO:0090091]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of focal adhesion assembly [GO:0051893]; regulation of gastrulation [GO:0010470]; regulation of microtubule cytoskeleton organization [GO:0070507]; vesicle targeting [GO:0006903] GO:0000226; GO:0000776; GO:0001578; GO:0002162; GO:0005737; GO:0005794; GO:0005813; GO:0005815; GO:0005876; GO:0005881; GO:0005925; GO:0005938; GO:0006903; GO:0007020; GO:0007026; GO:0007030; GO:0007052; GO:0008017; GO:0010458; GO:0010470; GO:0010634; GO:0010717; GO:0015630; GO:0016477; GO:0030010; GO:0030953; GO:0030981; GO:0031023; GO:0031111; GO:0031592; GO:0034453; GO:0040001; GO:0043515; GO:0045180; GO:0045921; GO:0051010; GO:0051294; GO:0051301; GO:0051497; GO:0051893; GO:0070507; GO:0072686; GO:0090091; GO:0090307; GO:1903690; GO:1904261 2139 XM_044321597.1 292 72 742 118 122 Q80TV8 4.79e-73 CLIP-associating protein 1 (Cytoplasmic linker-associated protein 1) Mus musculus (Mouse) astral microtubule organization [GO:0030953]; cell division [GO:0051301]; cell migration [GO:0016477]; establishment of cell polarity [GO:0030010]; establishment of mitotic spindle localization [GO:0040001]; establishment of spindle orientation [GO:0051294]; exit from mitosis [GO:0010458]; Golgi organization [GO:0007030]; microtubule anchoring [GO:0034453]; microtubule bundle formation [GO:0001578]; microtubule cytoskeleton organization [GO:0000226]; microtubule nucleation [GO:0007020]; microtubule organizing center organization [GO:0031023]; mitotic spindle assembly [GO:0090307]; mitotic spindle organization [GO:0007052]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of microtubule polymerization or depolymerization [GO:0031111]; negative regulation of stress fiber assembly [GO:0051497]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of exocytosis [GO:0045921]; positive regulation of extracellular matrix disassembly [GO:0090091]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of focal adhesion assembly [GO:0051893]; regulation of gastrulation [GO:0010470]; regulation of microtubule cytoskeleton organization [GO:0070507]; vesicle targeting [GO:0006903] GO:0000226; GO:0000776; GO:0001578; GO:0002162; GO:0005737; GO:0005794; GO:0005813; GO:0005815; GO:0005876; GO:0005881; GO:0005925; GO:0005938; GO:0006903; GO:0007020; GO:0007026; GO:0007030; GO:0007052; GO:0008017; GO:0010458; GO:0010470; GO:0010634; GO:0010717; GO:0015630; GO:0016477; GO:0030010; GO:0030953; GO:0030981; GO:0031023; GO:0031111; GO:0031592; GO:0034453; GO:0040001; GO:0043515; GO:0045180; GO:0045921; GO:0051010; GO:0051294; GO:0051301; GO:0051497; GO:0051893; GO:0070507; GO:0072686; GO:0090091; GO:0090307; GO:1903690; GO:1904261 2140 XM_044321597.1 292 72 742 118 122 Q80TV8 5.77e-49 CLIP-associating protein 1 (Cytoplasmic linker-associated protein 1) Mus musculus (Mouse) astral microtubule organization [GO:0030953]; cell division [GO:0051301]; cell migration [GO:0016477]; establishment of cell polarity [GO:0030010]; establishment of mitotic spindle localization [GO:0040001]; establishment of spindle orientation [GO:0051294]; exit from mitosis [GO:0010458]; Golgi organization [GO:0007030]; microtubule anchoring [GO:0034453]; microtubule bundle formation [GO:0001578]; microtubule cytoskeleton organization [GO:0000226]; microtubule nucleation [GO:0007020]; microtubule organizing center organization [GO:0031023]; mitotic spindle assembly [GO:0090307]; mitotic spindle organization [GO:0007052]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of microtubule polymerization or depolymerization [GO:0031111]; negative regulation of stress fiber assembly [GO:0051497]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of exocytosis [GO:0045921]; positive regulation of extracellular matrix disassembly [GO:0090091]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of focal adhesion assembly [GO:0051893]; regulation of gastrulation [GO:0010470]; regulation of microtubule cytoskeleton organization [GO:0070507]; vesicle targeting [GO:0006903] GO:0000226; GO:0000776; GO:0001578; GO:0002162; GO:0005737; GO:0005794; GO:0005813; GO:0005815; GO:0005876; GO:0005881; GO:0005925; GO:0005938; GO:0006903; GO:0007020; GO:0007026; GO:0007030; GO:0007052; GO:0008017; GO:0010458; GO:0010470; GO:0010634; GO:0010717; GO:0015630; GO:0016477; GO:0030010; GO:0030953; GO:0030981; GO:0031023; GO:0031111; GO:0031592; GO:0034453; GO:0040001; GO:0043515; GO:0045180; GO:0045921; GO:0051010; GO:0051294; GO:0051301; GO:0051497; GO:0051893; GO:0070507; GO:0072686; GO:0090091; GO:0090307; GO:1903690; GO:1904261 2141 XM_044317217.1 349 36 23 167 221 NA NA NA NA NA NA 2142 XM_044316792.1 384 265 299 394 460 O15078 0 Centrosomal protein of 290 kDa (Cep290) (Bardet-Biedl syndrome 14 protein) (Cancer/testis antigen 87) (CT87) (Nephrocystin-6) (Tumor antigen se2-2) Homo sapiens (Human) camera-type eye development [GO:0043010]; ciliary basal body-plasma membrane docking [GO:0097711]; ciliary transition zone assembly [GO:1905349]; cilium assembly [GO:0060271]; eye photoreceptor cell development [GO:0042462]; hindbrain development [GO:0030902]; kidney development [GO:0001822]; non-motile cilium assembly [GO:1905515]; otic vesicle formation [GO:0030916]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of intracellular protein transport [GO:0090316]; pronephros development [GO:0048793]; protein transport [GO:0015031]; regulation of establishment of protein localization [GO:0070201] GO:0001822; GO:0005576; GO:0005634; GO:0005737; GO:0005813; GO:0005814; GO:0005829; GO:0015031; GO:0016020; GO:0030902; GO:0030916; GO:0032391; GO:0032991; GO:0034451; GO:0035580; GO:0035869; GO:0036038; GO:0036064; GO:0042462; GO:0042802; GO:0043010; GO:0045893; GO:0048793; GO:0060271; GO:0070201; GO:0090316; GO:0097711; GO:1905349; GO:1905515 2143 XM_029342591.2 3389 2753 2270 3634 3394 P26007 3.22e-89 Integrin alpha-6 (VLA-6) [Cleaved into: Integrin alpha-6 heavy chain; Integrin alpha-6 light chain] Gallus gallus (Chicken) cell adhesion mediated by integrin [GO:0033627]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900] GO:0005178; GO:0007160; GO:0007229; GO:0008305; GO:0009897; GO:0009986; GO:0031994; GO:0033627; GO:0038132; GO:0046872; GO:0050900; GO:0098609 2144 XM_044325053.1 0 0 4 5 35 NA NA NA NA NA NA 2145 XM_044316873.1 35 0 0 0 0 NA NA NA NA NA NA 2146 XM_029328766.2 660 207 174 348 481 Q8N653 0 Leucine-zipper-like transcriptional regulator 1 (LZTR-1) Homo sapiens (Human) negative regulation of Ras protein signal transduction [GO:0046580]; protein ubiquitination [GO:0016567] GO:0005794; GO:0012505; GO:0016567; GO:0031267; GO:0031463; GO:0046580; GO:0055038 2147 XM_029350577.2 324 349 229 293 351 NA NA NA NA NA NA 2148 XM_029337264.2 292 264 199 290 224 NA NA NA NA NA NA 2149 XM_044314191.1 78 0 36 150 99 Q80XJ3 6.77e-93 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 2150 XM_044314191.1 78 0 36 150 99 Q80XJ3 1.03e-83 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 2151 XM_044314191.1 78 0 36 150 99 Q80XJ3 2.4e-82 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 2152 XM_044314191.1 78 0 36 150 99 Q80XJ3 1.1e-80 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 2153 XM_044314191.1 78 0 36 150 99 Q80XJ3 1.7e-78 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 2154 XM_044314191.1 78 0 36 150 99 Q80XJ3 6.18e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 2155 XM_044314191.1 78 0 36 150 99 Q80XJ3 1.11e-73 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 2156 XM_044314191.1 78 0 36 150 99 Q80XJ3 1.2e-72 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 2157 XM_044314191.1 78 0 36 150 99 Q80XJ3 1.98e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 2158 XM_044314191.1 78 0 36 150 99 Q80XJ3 1.98e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 2159 XM_029346562.2 4075 3035 2422 4135 3552 Q9P0L2 0 Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (EC 2.7.11.26) (MAP/microtubule affinity-regulating kinase 1) (PAR1 homolog c) (Par-1c) (Par1c) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; establishment of mitochondrion localization [GO:0051654]; intracellular signal transduction [GO:0035556]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of gene expression [GO:0010629]; neuron migration [GO:0001764]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]; regulation of dendrite development [GO:0050773]; regulation of neuron projection development [GO:0010975]; Wnt signaling pathway [GO:0016055] GO:0000226; GO:0000287; GO:0001764; GO:0001786; GO:0004674; GO:0005524; GO:0005546; GO:0005737; GO:0005856; GO:0005886; GO:0006468; GO:0007010; GO:0010628; GO:0010629; GO:0010719; GO:0010975; GO:0015630; GO:0016055; GO:0018105; GO:0030425; GO:0035556; GO:0048156; GO:0050321; GO:0050773; GO:0051654; GO:0070300; GO:0106310 2160 XM_044328501.1 78 81 208 142 87 Q9BYK8 2.32e-168 Helicase with zinc finger domain 2 (ATP-dependent helicase PRIC285) (Helicase with zinc finger 2, transcriptional coactivator) (PPAR-alpha-interacting complex protein 285) (PPAR-gamma DNA-binding domain-interacting protein 1) (PDIP1) (PPAR-gamma DBD-interacting protein 1) (Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein) (EC 3.6.4.-) Homo sapiens (Human) nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000184; GO:0003677; GO:0003723; GO:0003724; GO:0004540; GO:0005524; GO:0005654; GO:0005737; GO:0016020; GO:0030374; GO:0045944; GO:0046872 2161 XM_044328501.1 78 81 208 142 87 Q9BYK8 2.17e-96 Helicase with zinc finger domain 2 (ATP-dependent helicase PRIC285) (Helicase with zinc finger 2, transcriptional coactivator) (PPAR-alpha-interacting complex protein 285) (PPAR-gamma DNA-binding domain-interacting protein 1) (PDIP1) (PPAR-gamma DBD-interacting protein 1) (Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein) (EC 3.6.4.-) Homo sapiens (Human) nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000184; GO:0003677; GO:0003723; GO:0003724; GO:0004540; GO:0005524; GO:0005654; GO:0005737; GO:0016020; GO:0030374; GO:0045944; GO:0046872 2162 XM_044328501.1 78 81 208 142 87 Q9BYK8 4.59e-29 Helicase with zinc finger domain 2 (ATP-dependent helicase PRIC285) (Helicase with zinc finger 2, transcriptional coactivator) (PPAR-alpha-interacting complex protein 285) (PPAR-gamma DNA-binding domain-interacting protein 1) (PDIP1) (PPAR-gamma DBD-interacting protein 1) (Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein) (EC 3.6.4.-) Homo sapiens (Human) nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000184; GO:0003677; GO:0003723; GO:0003724; GO:0004540; GO:0005524; GO:0005654; GO:0005737; GO:0016020; GO:0030374; GO:0045944; GO:0046872 2163 XM_029337792.2 2247 48 282 407 402 B3EWY9 5.84e-28 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 2164 XM_029337792.2 2247 48 282 407 402 B3EWY9 8.2e-24 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 2165 XM_029341639.2 232 41 90 185 187 B8V7S0 0 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 2166 XM_029341639.2 232 41 90 185 187 B8V7S0 1.1e-176 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 2167 XM_044309643.1 0 0 0 78 0 Q9Z2W0 0 Aspartyl aminopeptidase (EC 3.4.11.21) Mus musculus (Mouse) proteolysis [GO:0006508] GO:0004177; GO:0005829; GO:0006508; GO:0008237; GO:0008270; GO:0042802 2168 XM_029349095.2 4620 4873 5165 4002 2363 NA NA NA NA NA NA 2169 XR_003824594.2 29 0 101 34 73 Q8WVS4 2.97e-81 Cytoplasmic dynein 2 intermediate chain 1 (Dynein 2 intermediate chain 1) (WD repeat-containing protein 60) Homo sapiens (Human) cilium assembly [GO:0060271]; embryonic skeletal system morphogenesis [GO:0048704]; intraciliary retrograde transport [GO:0035721]; intraciliary transport [GO:0042073]; microtubule-based movement [GO:0007018] GO:0000242; GO:0005615; GO:0005813; GO:0005868; GO:0005929; GO:0007018; GO:0035721; GO:0042073; GO:0045503; GO:0045504; GO:0048704; GO:0060271; GO:0097014; GO:0097542; GO:0097546 2170 XR_003825461.2 60 33 24 17 33 NA NA NA NA NA NA 2171 XM_044318721.1 0 28 0 0 16 NA NA NA NA NA NA 2172 XR_003824576.2 194 284 135 189 34 NA NA NA NA NA NA 2173 XR_006393783.1 2 7 2 9 4 NA NA NA NA NA NA 2174 XM_029335167.2 2663 2798 2123 2819 3382 Q6DF78 7.77e-128 Pyridoxal-dependent decarboxylase domain-containing protein 1 (EC 4.1.1.-) Xenopus laevis (African clawed frog) carboxylic acid metabolic process [GO:0019752] GO:0016831; GO:0019752; GO:0030170 2175 XM_029326369.2 42 0 0 0 0 NA NA NA NA NA NA 2176 XR_003825346.2 7 0 3 26 23 NA NA NA NA NA NA 2177 XR_006394209.1 28 18 29 23 85 NA NA NA NA NA NA 2178 XM_044318515.1 86 198 57 116 152 NA NA NA NA NA NA 2179 XM_044317161.1 363 254 290 310 480 O14841 0 5-oxoprolinase (EC 3.5.2.9) (5-oxo-L-prolinase) (5-OPase) (Pyroglutamase) Homo sapiens (Human) glutathione metabolic process [GO:0006749] GO:0005524; GO:0005829; GO:0006749; GO:0017168; GO:0042802 2180 XR_006394070.1 0 2 12 4 11 NA NA NA NA NA NA 2181 XM_044308443.1 10 16 0 0 0 NA NA NA NA NA NA 2182 XM_029330059.2 0 0 0 7 3 A1L1W9 1.94e-50 Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10) Danio rerio (Zebrafish) (Brachydanio rerio) aromatic amino acid transport [GO:0015801]; thyroid hormone transport [GO:0070327] GO:0005302; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0070327 2183 XM_044314505.1 1 1 13 3 2 NA NA NA NA NA NA 2184 XM_044308982.1 37 25 34 30 43 NA NA NA NA NA NA 2185 XM_029346163.2 507 467 318 529 511 Q5ZL91 0 Integrator complex subunit 7 (Int7) Gallus gallus (Chicken) cellular response to DNA damage stimulus [GO:0006974]; snRNA 3'-end processing [GO:0034472] GO:0005694; GO:0006974; GO:0032039; GO:0034472 2186 XM_044328202.1 1026 413 419 540 588 P48441 0 Alpha-L-iduronidase (EC 3.2.1.76) Mus musculus (Mouse) adult locomotory behavior [GO:0008344]; adult walking behavior [GO:0007628]; bone development [GO:0060348]; carbohydrate metabolic process [GO:0005975]; cartilage homeostasis [GO:1990079]; cell morphogenesis [GO:0000902]; chemical homeostasis [GO:0048878]; dermatan sulfate catabolic process [GO:0030209]; extracellular matrix organization [GO:0030198]; glycosaminoglycan catabolic process [GO:0006027]; heparan sulfate proteoglycan catabolic process [GO:0030200]; heparin catabolic process [GO:0030211]; limb morphogenesis [GO:0035108]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; memory [GO:0007613]; negative regulation of cartilage development [GO:0061037]; negative regulation of secretion of lysosomal enzymes [GO:0090341]; positive regulation of bone resorption [GO:0045780]; positive regulation of collagen catabolic process [GO:0120158]; skeletal system morphogenesis [GO:0048705]; visual learning [GO:0008542] GO:0000902; GO:0003940; GO:0004553; GO:0005102; GO:0005615; GO:0005764; GO:0005975; GO:0006027; GO:0007040; GO:0007613; GO:0007626; GO:0007628; GO:0008344; GO:0008542; GO:0030135; GO:0030198; GO:0030200; GO:0030209; GO:0030211; GO:0035108; GO:0043202; GO:0045780; GO:0048705; GO:0048878; GO:0060348; GO:0061037; GO:0090341; GO:0120158; GO:1990079 2187 XM_044322895.1 370 286 231 363 395 O42877 1.14e-35 rRNA-processing protein fcf2 Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) RNA processing [GO:0006396]; rRNA processing [GO:0006364] GO:0005634; GO:0005730; GO:0006364; GO:0006396 2188 XR_006394038.1 15 0 0 0 25 NA NA NA NA NA NA 2189 XM_029338468.2 461 588 356 488 421 Q5ZKR4 2.13e-68 Rab-like protein 3 Gallus gallus (Chicken) B cell differentiation [GO:0030183]; intracellular protein transport [GO:0006886]; natural killer cell differentiation [GO:0001779]; regulation of protein lipidation [GO:1903059]; regulation of Ras protein signal transduction [GO:0046578]; T cell differentiation in thymus [GO:0033077] GO:0001779; GO:0003924; GO:0005525; GO:0006886; GO:0012505; GO:0030183; GO:0033077; GO:0042803; GO:0046578; GO:1903059 2190 XM_029351953.2 1357 860 779 1218 701 NA NA NA NA NA NA 2191 XM_044318102.1 2 0 10 3 8 NA NA NA NA NA NA 2192 XM_029335895.2 0 7 4 0 31 NA NA NA NA NA NA 2193 XM_044319828.1 288 205 142 198 516 Q86U38 6.95e-66 Nucleolar protein 9 Homo sapiens (Human) endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000480]; endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000447]; endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000472]; ribosomal small subunit export from nucleus [GO:0000056] GO:0000056; GO:0000447; GO:0000472; GO:0000480; GO:0003723; GO:0005730; GO:0030686; GO:0030688 2194 XR_006394152.1 13 0 5 7 0 NA NA NA NA NA NA 2195 XM_044327862.1 0 12 0 6 2 NA NA NA NA NA NA 2196 XM_044320552.1 13 0 50 380 149 C0H692 4.55e-21 Small cysteine-rich protein 3 (Amil-SCRiP3) (SCRiP3) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0042151; GO:0090729 2197 XM_029352550.2 40 162 61 78 116 NA NA NA NA NA NA 2198 XM_029355490.2 1324 1061 903 2843 2820 A1A4N1 4.55e-84 Equilibrative nucleoside transporter 3 (Solute carrier family 29 member 3) Bos taurus (Bovine) NA GO:0005337; GO:0005765; GO:0031902 2199 XM_044316011.1 54 30 74 70 134 O77503 2.33e-130 Protein argonaute-2 (Argonaute2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (Protein slicer) Oryctolagus cuniculus (Rabbit) miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; miRNA-mediated gene silencing by mRNA destabilization [GO:0035279]; negative regulation of translational initiation [GO:0045947]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; pre-miRNA processing [GO:0031054]; regulation of DNA-templated transcription [GO:0006355]; RNA-mediated gene silencing [GO:0031047] GO:0000340; GO:0000932; GO:0005634; GO:0005844; GO:0005845; GO:0006355; GO:0016442; GO:0031047; GO:0031054; GO:0035197; GO:0035278; GO:0035279; GO:0045947; GO:0046872; GO:0060213; GO:0070551; GO:0070578; GO:1900153; GO:1990904 2200 XM_029355829.2 0 0 10 21 0 Q9EQC4 1.8e-65 Elongation of very long chain fatty acids protein 4 (EC 2.3.1.199) (3-keto acyl-CoA synthase Elovl4) (ELOVL fatty acid elongase 4) (ELOVL FA elongase 4) (Very long chain 3-ketoacyl-CoA synthase 4) (Very long chain 3-oxoacyl-CoA synthase 4) Mus musculus (Mouse) fatty acid elongation, monounsaturated fatty acid [GO:0034625]; fatty acid elongation, polyunsaturated fatty acid [GO:0034626]; fatty acid elongation, saturated fatty acid [GO:0019367]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; sphingolipid biosynthetic process [GO:0030148]; unsaturated fatty acid biosynthetic process [GO:0006636]; very long-chain fatty acid biosynthetic process [GO:0042761] GO:0005783; GO:0005789; GO:0006636; GO:0009922; GO:0019367; GO:0030148; GO:0034625; GO:0034626; GO:0035338; GO:0042761; GO:0102756 2201 XM_029336604.2 311 200 255 141 28 Q641E3 4.38e-31 Acyl-CoA-binding domain-containing protein 5 Xenopus laevis (African clawed frog) autophagy of peroxisome [GO:0030242] GO:0000062; GO:0005778; GO:0030242 2202 XR_006392561.1 41 0 5 5 43 F1R4Y7 1.84e-71 Centrosomal protein of 83 kDa (Cep83) (Coiled-coil domain-containing protein 41) Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; establishment of centrosome localization [GO:0051660] GO:0005737; GO:0005814; GO:0051660; GO:0060271; GO:0097539 2203 XM_029353556.2 0 163 88 0 0 NA NA NA NA NA NA 2204 XM_044310524.1 0 0 0 86 0 NA NA NA NA NA NA 2205 XR_006395866.1 929 341 244 563 293 P50430 1.6e-135 Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S) Rattus norvegicus (Rat) anterior head development [GO:0097065]; autophagy [GO:0006914]; central nervous system development [GO:0007417]; colon epithelial cell migration [GO:0061580]; dermatan sulfate catabolic process [GO:0030209]; positive regulation of neuron projection development [GO:0010976]; regulation of epithelial cell migration [GO:0010632]; response to estrogen [GO:0043627]; response to methylmercury [GO:0051597]; response to nutrient [GO:0007584]; response to pH [GO:0009268] GO:0003943; GO:0004065; GO:0005739; GO:0005764; GO:0005791; GO:0005794; GO:0006914; GO:0007417; GO:0007584; GO:0008484; GO:0009268; GO:0009986; GO:0010632; GO:0010976; GO:0030209; GO:0043627; GO:0043890; GO:0046872; GO:0051597; GO:0061580; GO:0097065 2206 XM_044310245.1 0 0 0 0 44 Q5F371 2.07e-52 Protein strawberry notch homolog 1 Gallus gallus (Chicken) regulation of DNA-templated transcription [GO:0006355]; regulation of response to stimulus [GO:0048583] GO:0005634; GO:0006355; GO:0031490; GO:0042393; GO:0048583 2207 XM_044310245.1 0 0 0 0 44 Q5F371 2.07e-52 Protein strawberry notch homolog 1 Gallus gallus (Chicken) regulation of DNA-templated transcription [GO:0006355]; regulation of response to stimulus [GO:0048583] GO:0005634; GO:0006355; GO:0031490; GO:0042393; GO:0048583 2208 XR_006396493.1 0 0 0 0 10 NA NA NA NA NA NA 2209 XR_006393187.1 64 74 166 101 174 NA NA NA NA NA NA 2210 XM_029329501.2 352 174 66 215 128 NA NA NA NA NA NA 2211 XR_006395476.1 35 12 8 15 8 NA NA NA NA NA NA 2212 XM_044323250.1 530 269 366 676 1284 NA NA NA NA NA NA 2213 XM_029341934.2 1915 1724 1019 1026 659 P25490 1.39e-93 Transcriptional repressor protein YY1 (Delta transcription factor) (INO80 complex subunit S) (NF-E1) (Yin and yang 1) (YY-1) Homo sapiens (Human) anterior/posterior pattern specification [GO:0009952]; B cell differentiation [GO:0030183]; camera-type eye morphogenesis [GO:0048593]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to interleukin-1 [GO:0071347]; cellular response to UV [GO:0034644]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; negative regulation of cell growth involved in cardiac muscle cell development [GO:0061052]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of miRNA transcription [GO:1902894]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of telomere maintenance in response to DNA damage [GO:1904507]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell cycle [GO:0051726]; regulation of chromosome organization [GO:0033044]; regulation of DNA repair [GO:0006282]; regulation of DNA replication [GO:0006275]; regulation of DNA strand elongation [GO:0060382]; regulation of embryonic development [GO:0045995]; regulation of transcription by RNA polymerase II [GO:0006357]; response to prostaglandin F [GO:0034696]; response to UV-C [GO:0010225]; RNA localization [GO:0006403]; spermatogenesis [GO:0007283]; telomere maintenance [GO:0000723] GO:0000122; GO:0000400; GO:0000723; GO:0000724; GO:0000976; GO:0000978; GO:0000981; GO:0000987; GO:0001217; GO:0001227; GO:0001228; GO:0003677; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005667; GO:0005677; GO:0005737; GO:0006275; GO:0006282; GO:0006338; GO:0006357; GO:0006403; GO:0006974; GO:0007283; GO:0009952; GO:0010225; GO:0010628; GO:0010629; GO:0016363; GO:0030183; GO:0031011; GO:0031519; GO:0032688; GO:0033044; GO:0034644; GO:0034696; GO:0045739; GO:0045893; GO:0045944; GO:0045995; GO:0046332; GO:0046872; GO:0048593; GO:0051726; GO:0060382; GO:0061052; GO:0071347; GO:0071707; GO:0140297; GO:1902894; GO:1904507; GO:1990837 2214 XR_006397640.1 2 17 6 18 8 NA NA NA NA NA NA 2215 XM_029328613.2 315 891 313 579 663 Q91X96 2.53e-36 Guanine nucleotide exchange factor MSS4 (Rab-interacting factor) Mus musculus (Mouse) post-Golgi vesicle-mediated transport [GO:0006892]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264] GO:0005085; GO:0005829; GO:0006892; GO:0007264; GO:0008270; GO:0015031; GO:0016020 2216 XM_029334602.2 643 910 554 430 597 Q91ZV7 4.44e-50 Plexin domain-containing protein 1 (Tumor endothelial marker 7) Mus musculus (Mouse) spinal cord development [GO:0021510] GO:0005737; GO:0005886; GO:0005923; GO:0021510; GO:0030425; GO:0043025; GO:0043235 2217 XM_029330036.2 0 4 0 9 0 NA NA NA NA NA NA 2218 XM_029341975.2 654 491 578 452 513 Q8BZQ7 0 Anaphase-promoting complex subunit 2 (APC2) (Cyclosome subunit 2) Mus musculus (Mouse) cell differentiation [GO:0030154]; cell division [GO:0051301]; metaphase/anaphase transition of mitotic cell cycle [GO:0007091]; negative regulation of gene expression [GO:0010629]; nervous system development [GO:0007399]; positive regulation of axon extension [GO:0045773]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse maturation [GO:0090129]; positive regulation of synaptic plasticity [GO:0031915]; protein K11-linked ubiquitination [GO:0070979]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0005634; GO:0005680; GO:0006511; GO:0007091; GO:0007399; GO:0010629; GO:0030154; GO:0031625; GO:0031915; GO:0045773; GO:0050775; GO:0051301; GO:0070979; GO:0090129 2219 XM_029351324.2 3698 3212 2739 2392 3015 Q6P0I8 4.77e-65 Exosome complex component MTR3 (Exosome component 6) (mRNA transport regulator 3 homolog) Danio rerio (Zebrafish) (Brachydanio rerio) nuclear mRNA surveillance [GO:0071028]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; U4 snRNA 3'-end processing [GO:0034475] GO:0000176; GO:0000177; GO:0000178; GO:0003723; GO:0005730; GO:0006364; GO:0016075; GO:0034427; GO:0034475; GO:0071028; GO:0071051 2220 XM_044325350.1 43 20 28 56 116 P48733 1.52e-27 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Bos taurus (Bovine) antibacterial innate immune response [GO:0140367]; defense response to Gram-negative bacterium [GO:0050829] GO:0000922; GO:0005201; GO:0005509; GO:0005576; GO:0005929; GO:0016020; GO:0016323; GO:0016324; GO:0031012; GO:0050829; GO:0060170; GO:0140367 2221 XR_006393751.1 20 2 23 72 65 NA NA NA NA NA NA 2222 XM_044307674.1 13 1 22 0 99 NA NA NA NA NA NA 2223 XM_044307242.1 1297 876 945 1006 1194 NA NA NA NA NA NA 2224 XM_044307926.1 0 0 0 0 7 NA NA NA NA NA NA 2225 XM_029333645.2 1077 1125 535 618 613 Q5R592 2.85e-49 DNA-directed RNA polymerases I, II, and III subunit RPABC2 (RNA polymerases I, II, and III subunit ABC2) (DNA-directed RNA polymerase II subunit F) (RPB6 homolog) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) transcription by RNA polymerase II [GO:0006366] GO:0003677; GO:0003899; GO:0005634; GO:0005665; GO:0006366 2226 XM_029358169.2 386 375 258 460 400 NA NA NA NA NA NA 2227 XM_029352390.2 861 411 569 686 853 Q921X9 2.2e-117 Protein disulfide-isomerase A5 (EC 5.3.4.1) (Protein disulfide isomerase-related protein) Mus musculus (Mouse) protein folding [GO:0006457] GO:0003756; GO:0005783; GO:0005788; GO:0006457; GO:0015035 2228 XM_029352390.2 861 411 569 686 853 Q921X9 6.14e-50 Protein disulfide-isomerase A5 (EC 5.3.4.1) (Protein disulfide isomerase-related protein) Mus musculus (Mouse) protein folding [GO:0006457] GO:0003756; GO:0005783; GO:0005788; GO:0006457; GO:0015035 2229 XM_029352390.2 861 411 569 686 853 Q921X9 6.76e-27 Protein disulfide-isomerase A5 (EC 5.3.4.1) (Protein disulfide isomerase-related protein) Mus musculus (Mouse) protein folding [GO:0006457] GO:0003756; GO:0005783; GO:0005788; GO:0006457; GO:0015035 2230 XM_044322486.1 1 0 0 0 13 NA NA NA NA NA NA 2231 XR_003827698.2 1 0 0 8 0 NA NA NA NA NA NA 2232 XM_044313938.1 1 0 6 0 11 B8VIU6 1.18e-57 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 2233 XM_044313790.1 1198 586 455 1423 1858 B1AVY7 4.29e-69 Kinesin-like protein KIF16B Mus musculus (Mouse) cellular response to type II interferon [GO:0071346]; early endosome to late endosome transport [GO:0045022]; endoderm development [GO:0007492]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; formation of primary germ layer [GO:0001704]; Golgi to endosome transport [GO:0006895]; microtubule-based movement [GO:0007018]; receptor catabolic process [GO:0032801]; regulation of receptor recycling [GO:0001919] GO:0001704; GO:0001919; GO:0003777; GO:0005524; GO:0005547; GO:0005737; GO:0005768; GO:0005769; GO:0005819; GO:0005829; GO:0005871; GO:0005874; GO:0006895; GO:0007018; GO:0007173; GO:0007492; GO:0008017; GO:0008543; GO:0008574; GO:0016887; GO:0031267; GO:0031901; GO:0032266; GO:0032801; GO:0043325; GO:0045022; GO:0045335; GO:0071346; GO:0080025 2234 XM_044323444.1 71 0 170 0 0 NA NA NA NA NA NA 2235 XM_029349192.2 26106 30346 22133 23985 25337 P05426 2.11e-107 60S ribosomal protein L7 Rattus norvegicus (Rat) liver regeneration [GO:0097421]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; ribosomal large subunit biogenesis [GO:0042273]; rRNA processing [GO:0006364] GO:0000463; GO:0003677; GO:0003723; GO:0003729; GO:0003735; GO:0005840; GO:0005844; GO:0006364; GO:0008097; GO:0014069; GO:0022625; GO:0022626; GO:0031672; GO:0042273; GO:0042802; GO:0045202; GO:0097421; GO:1990904 2236 XM_029337410.2 2532 3189 2104 3437 3661 P13234 1.84e-121 Calcium/calmodulin-dependent protein kinase type IV (CaMK IV) (EC 2.7.11.17) (CaM kinase-GR) (Calspermin) Rattus norvegicus (Rat) adaptive immune response [GO:0002250]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; long-term memory [GO:0007616]; myeloid dendritic cell differentiation [GO:0043011]; neuron-neuron synaptic transmission [GO:0007270]; nucleocytoplasmic transport [GO:0006913]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of protein export from nucleus [GO:0046827]; postsynapse to nucleus signaling pathway [GO:0099527]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165] GO:0001650; GO:0002250; GO:0004683; GO:0005516; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0006468; GO:0006913; GO:0006954; GO:0007165; GO:0007270; GO:0007616; GO:0009931; GO:0018105; GO:0035556; GO:0043011; GO:0045893; GO:0046777; GO:0046827; GO:0098794; GO:0098978; GO:0098982; GO:0099170; GO:0099527; GO:0106310 2237 XM_029336849.2 3572 3493 1786 2668 2648 Q9W2N0 5.72e-134 F-actin-capping protein subunit alpha Drosophila melanogaster (Fruit fly) actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; barbed-end actin filament capping [GO:0051016]; cell morphogenesis [GO:0000902]; germarium-derived oocyte fate determination [GO:0007294]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of filopodium assembly [GO:0051490]; negative regulation of JNK cascade [GO:0046329]; nuclear envelope budding [GO:0140591]; positive regulation of filopodium assembly [GO:0051491]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; wing disc development [GO:0035220] GO:0000902; GO:0007015; GO:0007294; GO:0008290; GO:0010591; GO:0016324; GO:0030018; GO:0030036; GO:0030837; GO:0035220; GO:0046329; GO:0046982; GO:0051015; GO:0051016; GO:0051489; GO:0051490; GO:0051491; GO:0071203; GO:0140591 2238 XM_029355521.2 341 385 288 653 626 P05455 4.47e-62 Lupus La protein (La autoantigen) (La ribonucleoprotein) (Sjoegren syndrome type B antigen) (SS-B) Homo sapiens (Human) histone mRNA metabolic process [GO:0008334]; IRES-dependent viral translational initiation [GO:0075522]; nuclear histone mRNA catabolic process [GO:0071045]; protein localization to cytoplasmic stress granule [GO:1903608]; tRNA 3'-end processing [GO:0042780]; tRNA 5'-leader removal [GO:0001682]; tRNA export from nucleus [GO:0006409]; tRNA modification [GO:0006400]; tRNA processing [GO:0008033] GO:0000049; GO:0000781; GO:0001682; GO:0003677; GO:0003723; GO:0003729; GO:0005634; GO:0005737; GO:0006400; GO:0006409; GO:0008033; GO:0008266; GO:0008334; GO:0042780; GO:0071045; GO:0075522; GO:1903608; GO:1990825; GO:1990904 2239 XM_029347172.2 70 12 24 4 18 Q2TB18 1.13e-72 Protein asteroid homolog 1 Homo sapiens (Human) NA GO:0004518 2240 XM_044327237.1 94 8 0 19 0 Q90481 1.55e-34 Homeobox protein Nkx-2.2a (Homeobox protein NK-2 homolog B-A) Danio rerio (Zebrafish) (Brachydanio rerio) cell differentiation [GO:0030154]; endocrine pancreas development [GO:0031018]; floor plate development [GO:0033504]; floor plate formation [GO:0021508]; glial cell migration [GO:0008347]; motor neuron axon guidance [GO:0008045]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357]; Schwann cell development [GO:0014044]; spinal cord oligodendrocyte cell differentiation [GO:0021529]; spinal cord oligodendrocyte cell fate specification [GO:0021530]; ventral spinal cord interneuron differentiation [GO:0021514] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0008045; GO:0008347; GO:0014044; GO:0021508; GO:0021514; GO:0021529; GO:0021530; GO:0030154; GO:0031018; GO:0033504; GO:0045893 2241 XR_006395174.1 173 53 43 137 21 NA NA NA NA NA NA 2242 XR_006393774.1 29 34 56 30 35 NA NA NA NA NA NA 2243 XR_006397176.1 41 50 0 90 0 NA NA NA NA NA NA 2244 XM_044324042.1 23465 33424 20045 28673 21432 Q95VY2 3.59e-37 Translationally-controlled tumor protein homolog (TCTP) Branchiostoma belcheri (Amphioxus) NA GO:0005737 2245 XR_006392127.1 195 149 100 204 261 NA NA NA NA NA NA 2246 XR_006392073.1 0 30 25 4 0 NA NA NA NA NA NA 2247 XR_006393611.1 15 0 31 1 1 NA NA NA NA NA NA 2248 XM_044313121.1 87 64 61 50 72 Q8CHP0 6.55e-51 Zinc finger CCCH domain-containing protein 3 (Smad-interacting CPSF-like factor) Mus musculus (Mouse) mRNA 3'-end processing [GO:0031124]; mRNA transport [GO:0051028]; positive regulation of activin receptor signaling pathway [GO:0032927]; regulation of mRNA polyadenylation [GO:1900363] GO:0003677; GO:0005634; GO:0005847; GO:0031124; GO:0032927; GO:0046332; GO:0046872; GO:0051028; GO:0070412; GO:1900363 2249 XM_044314073.1 77 192 50 17 127 NA NA NA NA NA NA 2250 XR_006396919.1 112 36 55 109 105 G5ECX0 2.33e-24 Latrophilin-like protein LAT-2 Caenorhabditis elegans adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; self proteolysis [GO:0097264] GO:0004175; GO:0004930; GO:0005886; GO:0007166; GO:0007189; GO:0030246; GO:0097264 2251 XM_029345580.2 0 18 2 6 9 P42264 1.22e-81 Glutamate receptor ionotropic, kainate 3 (GluK3) (Glutamate receptor 7) (GluR-7) (GluR7) Rattus norvegicus (Rat) chemical synaptic transmission [GO:0007268]; G protein-coupled glutamate receptor signaling pathway [GO:0007216]; glutamate receptor signaling pathway [GO:0007215]; ion transmembrane transport [GO:0034220]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; regulation of membrane potential [GO:0042391]; regulation of presynaptic membrane potential [GO:0099505]; synaptic transmission, glutamatergic [GO:0035249] GO:0001640; GO:0004970; GO:0005886; GO:0007215; GO:0007216; GO:0007268; GO:0008066; GO:0015276; GO:0015277; GO:0030424; GO:0030425; GO:0032839; GO:0032983; GO:0034220; GO:0035249; GO:0038023; GO:0042391; GO:0042734; GO:0043195; GO:0043204; GO:0045211; GO:0050804; GO:0051967; GO:0098978; GO:0099505; GO:0099507; GO:1904315 2252 XM_044321364.1 0 18 68 433 74 Q5VXM1 5.74e-29 CUB domain-containing protein 2 Homo sapiens (Human) NA GO:0005576 2253 XM_044326238.1 348 415 280 565 402 Q9NU19 2.79e-113 TBC1 domain family member 22B Homo sapiens (Human) activation of GTPase activity [GO:0090630] GO:0005096; GO:0071889; GO:0090630 2254 XM_044319517.1 81 208 91 141 104 NA NA NA NA NA NA 2255 XM_044315391.1 18 1 3 1 12 B8VIU6 3.01e-38 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 2256 XM_044328797.1 1 2 7 3 36 NA NA NA NA NA NA 2257 XM_044325892.1 835 627 428 441 596 Q0V9A9 5.87e-108 Endoribonuclease LACTB2 (Beta-lactamase-like protein 2) (EC 3.1.27.-) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502] GO:0003727; GO:0004521; GO:0005759; GO:0008270; GO:0090502 2258 XM_044328533.1 0 0 0 27 0 Q8BYA0 0 Tubulin-specific chaperone D (Beta-tubulin cofactor D) (Tubulin-folding cofactor D) Mus musculus (Mouse) adherens junction assembly [GO:0034333]; bicellular tight junction assembly [GO:0070830]; cell morphogenesis involved in neuron differentiation [GO:0048667]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of microtubule polymerization [GO:0031115]; post-chaperonin tubulin folding pathway [GO:0007023]; protein folding [GO:0006457]; tubulin complex assembly [GO:0007021] GO:0000226; GO:0000278; GO:0005096; GO:0005737; GO:0005813; GO:0005912; GO:0005923; GO:0006457; GO:0007021; GO:0007023; GO:0010812; GO:0016328; GO:0031115; GO:0034333; GO:0048487; GO:0048667; GO:0070830 2259 XM_029345775.2 21 22 9 61 32 O43614 1.11e-42 Orexin receptor type 2 (Ox-2-R) (Ox2-R) (Ox2R) (Hypocretin receptor type 2) Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; circadian sleep/wake cycle process [GO:0022410]; feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; locomotion [GO:0040011]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; regulation of circadian sleep/wake cycle, wakefulness [GO:0010840]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0004930; GO:0005886; GO:0007186; GO:0007200; GO:0007218; GO:0007268; GO:0007631; GO:0008188; GO:0010840; GO:0016499; GO:0017046; GO:0022410; GO:0040011; GO:0045202; GO:0051480 2260 XM_044314481.1 0 245 508 959 97 Q9NZJ4 0 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 2261 XM_044314481.1 0 245 508 959 97 Q9NZJ4 2.23e-52 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 2262 XM_044314481.1 0 245 508 959 97 Q9NZJ4 8.69e-43 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 2263 XM_044314481.1 0 245 508 959 97 Q9NZJ4 2.23e-41 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 2264 XM_044311056.1 925 191 191 736 315 P16157 1.71e-77 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 2265 XM_044311056.1 925 191 191 736 315 P16157 5.84e-70 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 2266 XM_044311056.1 925 191 191 736 315 P16157 2.5e-66 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 2267 XM_044311056.1 925 191 191 736 315 P16157 5.11e-61 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 2268 XM_044311056.1 925 191 191 736 315 P16157 1.16e-48 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 2269 XM_044311056.1 925 191 191 736 315 P16157 2.99e-40 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 2270 XM_044325007.1 0 0 0 8 6 NA NA NA NA NA NA 2271 XM_044327961.1 527 532 348 657 429 Q91981 3.74e-32 Homeobox protein OTX2 (zOTX2) (Orthodenticle homolog 2) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to alcohol [GO:0097306]; cerebellum development [GO:0021549]; hindbrain development [GO:0030902]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; regulation of transcription by RNA polymerase II [GO:0006357]; retinal pigment epithelium development [GO:0003406] GO:0000978; GO:0000981; GO:0003406; GO:0005634; GO:0006357; GO:0021549; GO:0030901; GO:0030902; GO:0030917; GO:0097306 2272 XM_044309273.1 0 0 0 0 9 NA NA NA NA NA NA 2273 XM_029325105.2 399 135 110 179 215 Q3KQ71 2.89e-32 Sodium channel modifier 1 Xenopus laevis (African clawed frog) alternative mRNA splicing, via spliceosome [GO:0000380] GO:0000380; GO:0016607; GO:0046872 2274 XM_044313253.1 162 167 239 77 17 Q04637 2.17e-176 Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G 1) (eIF-4G1) (p220) Homo sapiens (Human) behavioral fear response [GO:0001662]; cap-dependent translational initiation [GO:0002191]; cellular macromolecule biosynthetic process [GO:0034645]; cellular response to nutrient levels [GO:0031669]; energy homeostasis [GO:0097009]; lung development [GO:0030324]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of autophagy [GO:0010507]; negative regulation of neuron death [GO:1901215]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; neuron differentiation [GO:0030182]; positive regulation of cell death [GO:0010942]; positive regulation of cell growth [GO:0030307]; positive regulation of eukaryotic translation initiation factor 4F complex assembly [GO:1905537]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of mRNA cap binding [GO:1905612]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of translation in response to endoplasmic reticulum stress [GO:0036493]; regulation of cellular response to stress [GO:0080135]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of polysome binding [GO:1905696]; regulation of presynapse assembly [GO:1905606]; regulation of translational initiation [GO:0006446]; response to ethanol [GO:0045471]; translation [GO:0006412]; translational initiation [GO:0006413] GO:0001662; GO:0002191; GO:0003723; GO:0003729; GO:0003743; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0005844; GO:0006412; GO:0006413; GO:0006446; GO:0008135; GO:0008190; GO:0010494; GO:0010507; GO:0010801; GO:0010942; GO:0016020; GO:0016281; GO:0030182; GO:0030307; GO:0030324; GO:0031369; GO:0031669; GO:0033138; GO:0034645; GO:0035278; GO:0036493; GO:0042802; GO:0045471; GO:0045666; GO:0051247; GO:0060090; GO:0060964; GO:0080135; GO:0097009; GO:0098794; GO:1900087; GO:1901215; GO:1905537; GO:1905606; GO:1905612; GO:1905696 2275 XM_044318869.1 819 780 426 550 568 Q9BSW2 7.32e-56 EF-hand calcium-binding domain-containing protein 4B (Calcium release-activated calcium channel regulator 2A) (CRAC channel regulator 2A) (Calcium release-activated channel regulator 2A) (Ras-related protein Rab-46) Homo sapiens (Human) activation of store-operated calcium channel activity [GO:0032237]; endosomal transport [GO:0016197]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of JNK cascade [GO:0046330]; response to histamine [GO:0034776]; store-operated calcium entry [GO:0002115]; T-helper 1 cell differentiation [GO:0045063] GO:0000139; GO:0001772; GO:0002115; GO:0003924; GO:0005509; GO:0005525; GO:0005576; GO:0005737; GO:0005815; GO:0005886; GO:0016020; GO:0016197; GO:0031982; GO:0032237; GO:0032588; GO:0033093; GO:0034776; GO:0035580; GO:0045063; GO:0046330; GO:0051928 2276 XM_044318869.1 819 780 426 550 568 Q9BSW2 3.08e-35 EF-hand calcium-binding domain-containing protein 4B (Calcium release-activated calcium channel regulator 2A) (CRAC channel regulator 2A) (Calcium release-activated channel regulator 2A) (Ras-related protein Rab-46) Homo sapiens (Human) activation of store-operated calcium channel activity [GO:0032237]; endosomal transport [GO:0016197]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of JNK cascade [GO:0046330]; response to histamine [GO:0034776]; store-operated calcium entry [GO:0002115]; T-helper 1 cell differentiation [GO:0045063] GO:0000139; GO:0001772; GO:0002115; GO:0003924; GO:0005509; GO:0005525; GO:0005576; GO:0005737; GO:0005815; GO:0005886; GO:0016020; GO:0016197; GO:0031982; GO:0032237; GO:0032588; GO:0033093; GO:0034776; GO:0035580; GO:0045063; GO:0046330; GO:0051928 2277 XM_029332836.2 47 23 17 35 33 NA NA NA NA NA NA 2278 XR_006395820.1 9 88 3 21 23 NA NA NA NA NA NA 2279 XM_029340501.2 554 708 353 739 618 Q5EAB6 0 Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGnT1) (EC 2.4.1.-) Bos taurus (Bovine) O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493] GO:0000139; GO:0006493; GO:0008375; GO:0016020; GO:0016266; GO:0030145 2280 XM_029345910.2 135 0 117 153 102 NA NA NA NA NA NA 2281 XM_029345457.2 5100 4022 3181 4571 5327 NA NA NA NA NA NA 2282 XM_044328458.1 882 517 358 616 503 Q96HU1 0 Small G protein signaling modulator 3 (Merlin-associated protein) (RUN and TBC1 domain-containing protein 3) (Rab-GTPase-activating protein-like protein) (RabGAPLP) Homo sapiens (Human) activation of GTPase activity [GO:0090630]; cell cycle [GO:0007049]; plasma membrane to endosome transport [GO:0048227]; positive regulation of GTPase activity [GO:0043547]; positive regulation of protein catabolic process [GO:0045732]; Rap protein signal transduction [GO:0032486]; regulation of cell cycle [GO:0051726]; regulation of Rab protein signal transduction [GO:0032483] GO:0005096; GO:0005829; GO:0005921; GO:0007049; GO:0031267; GO:0032483; GO:0032486; GO:0043547; GO:0045732; GO:0048227; GO:0051726; GO:0090630 2283 XM_029346643.2 152 242 109 193 100 P58545 4.74e-22 BTB/POZ domain-containing protein 3 Mus musculus (Mouse) cerebral cortex development [GO:0021987]; dendrite morphogenesis [GO:0048813]; neurogenesis [GO:0022008] GO:0005634; GO:0005829; GO:0021987; GO:0022008; GO:0042802; GO:0048813 2284 XM_044322566.1 0 0 27 0 0 NA NA NA NA NA NA 2285 XM_029330266.2 0 0 30 44 52 Q32LQ4 1.78e-110 Betaine--homocysteine S-methyltransferase 1 (EC 2.1.1.5) Danio rerio (Zebrafish) (Brachydanio rerio) amino-acid betaine catabolic process [GO:0006579]; digestive system development [GO:0055123]; L-methionine salvage [GO:0071267]; methionine biosynthetic process [GO:0009086]; methylation [GO:0032259]; type B pancreatic cell development [GO:0003323] GO:0003323; GO:0005829; GO:0006579; GO:0008270; GO:0009086; GO:0032259; GO:0047150; GO:0055123; GO:0071267 2286 XM_044322160.1 6263 7824 3878 5237 6131 B9GCH9 0 Urease (EC 3.5.1.5) (Urea amidohydrolase) Oryza sativa subsp. japonica (Rice) urea catabolic process [GO:0043419] GO:0009039; GO:0016151; GO:0035550; GO:0043419 2287 XM_044306939.1 132 25 73 58 120 NA NA NA NA NA NA 2288 XM_029328578.2 0 0 0 0 22 P35348 3.7e-36 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) (Alpha-adrenergic receptor 1c) Homo sapiens (Human) activation of phospholipase C activity [GO:0007202]; adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; adult heart development [GO:0007512]; aging [GO:0007568]; apoptotic process [GO:0006915]; calcium ion transport into cytosol [GO:0060402]; cell growth involved in cardiac muscle cell development [GO:0061049]; cell-cell signaling [GO:0007267]; G protein-coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; micturition [GO:0060073]; multicellular organism aging [GO:0010259]; negative regulation of autophagy [GO:0010507]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure [GO:0001985]; negative regulation of Rho protein signal transduction [GO:0035024]; neuron-glial cell signaling [GO:0150099]; norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001994]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; pilomotor reflex [GO:0097195]; positive regulation of action potential [GO:0045760]; positive regulation of cardiac muscle contraction [GO:0060452]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; positive regulation of systemic arterial blood pressure [GO:0003084]; positive regulation of the force of heart contraction by epinephrine-norepinephrine [GO:0001997]; positive regulation of vasoconstriction [GO:0045907]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; response to hormone [GO:0009725]; response to xenobiotic stimulus [GO:0009410]; signal transduction [GO:0007165]; smooth muscle contraction [GO:0006939] GO:0000165; GO:0001985; GO:0001994; GO:0001996; GO:0001997; GO:0003084; GO:0004930; GO:0004937; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0005901; GO:0006915; GO:0006939; GO:0007165; GO:0007186; GO:0007200; GO:0007202; GO:0007204; GO:0007267; GO:0007512; GO:0007568; GO:0008285; GO:0009410; GO:0009725; GO:0010259; GO:0010507; GO:0010613; GO:0030018; GO:0030315; GO:0031965; GO:0032230; GO:0035024; GO:0035556; GO:0042734; GO:0043231; GO:0043410; GO:0045211; GO:0045760; GO:0045907; GO:0045987; GO:0046982; GO:0060073; GO:0060402; GO:0060452; GO:0061049; GO:0070374; GO:0071880; GO:0090037; GO:0097195; GO:0098691; GO:0098978; GO:0098982; GO:0099171; GO:0150099; GO:1903997 2289 XM_044314222.1 46 25 213 79 301 NA NA NA NA NA NA 2290 XM_044327478.1 77 722 370 571 747 Q99759 9.24e-42 Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3) Homo sapiens (Human) blood vessel development [GO:0001568]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; negative regulation of cellular senescence [GO:2000773]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell proliferation in bone marrow [GO:0071864]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of p38MAPK cascade [GO:1900745]; protein autophosphorylation [GO:0046777] GO:0000165; GO:0001568; GO:0004672; GO:0004674; GO:0004709; GO:0005524; GO:0005737; GO:0005829; GO:0035556; GO:0043123; GO:0046777; GO:0046872; GO:0071864; GO:0090050; GO:0106310; GO:1900745; GO:2000773 2291 XM_044323159.1 0 11 0 9 0 Q09575 5.53e-40 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 2292 XM_029334287.2 651 1312 376 692 297 NA NA NA NA NA NA 2293 XR_006394563.1 16 0 0 0 0 NA NA NA NA NA NA 2294 XR_006396794.1 395 339 27 127 803 Q6DG99 3.24e-27 BTB/POZ domain-containing protein KCTD6 Danio rerio (Zebrafish) (Brachydanio rerio) protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567] GO:0016567; GO:0051260 2295 XR_006396794.1 395 339 27 127 803 Q6DG99 4.32e-25 BTB/POZ domain-containing protein KCTD6 Danio rerio (Zebrafish) (Brachydanio rerio) protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567] GO:0016567; GO:0051260 2296 XM_044322227.1 117 69 44 106 103 NA NA NA NA NA NA 2297 XM_029328475.2 488 168 206 235 309 NA NA NA NA NA NA 2298 XM_044328368.1 22 23 6 16 27 NA NA NA NA NA NA 2299 XM_044307950.1 0 10 11 21 0 NA NA NA NA NA NA 2300 XM_044326850.1 0 106 129 0 0 NA NA NA NA NA NA 2301 XM_029326894.2 1402 678 890 1115 747 P92204 9.43e-21 Negative elongation factor E Drosophila melanogaster (Fruit fly) negative regulation of DNA-templated transcription, elongation [GO:0032785]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription elongation by RNA polymerase II [GO:0034244]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000122; GO:0003723; GO:0003729; GO:0005634; GO:0005694; GO:0008023; GO:0017053; GO:0032021; GO:0032785; GO:0034244; GO:0045944 2302 XM_044320766.1 47 18 29 20 16 P04323 1.21e-62 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 2303 XM_029349208.2 0 14 23 42 23 NA NA NA NA NA NA 2304 XM_044323499.1 45 40 30 70 117 NA NA NA NA NA NA 2305 XM_029343400.2 77 37 10 134 38 Q8BHP7 1.41e-44 Olfactomedin-like protein 2A (Photomedin-1) Mus musculus (Mouse) extracellular matrix organization [GO:0030198]; signal transduction [GO:0007165] GO:0005615; GO:0007165; GO:0030198; GO:0031012; GO:0042802; GO:0050840 2306 XR_006395230.1 52 13 6 82 88 NA NA NA NA NA NA 2307 XM_029337353.2 248 163 113 407 332 NA NA NA NA NA NA 2308 XM_029338953.2 11 32 58 0 22 NA NA NA NA NA NA 2309 XM_044328186.1 2099 2101 1872 2742 2526 NA NA NA NA NA NA 2310 XM_044312797.1 2451 127 1598 0 781 Q4KLE6 5.9e-75 N-terminal Xaa-Pro-Lys N-methyltransferase 1-B (EC 2.1.1.244) (Alpha N-terminal protein methyltransferase 1A-B) (Methyltransferase-like protein 11A-B) (X-Pro-Lys N-terminal protein methyltransferase 1A-B) (NTM1A-B) Xenopus laevis (African clawed frog) chromosome segregation [GO:0007059]; histone methylation [GO:0016571]; N-terminal peptidyl-glycine methylation [GO:0018013]; N-terminal peptidyl-proline dimethylation [GO:0018016]; N-terminal peptidyl-serine dimethylation [GO:0035572]; N-terminal peptidyl-serine trimethylation [GO:0035573]; spindle organization [GO:0007051] GO:0005634; GO:0007051; GO:0007059; GO:0008276; GO:0016571; GO:0018013; GO:0018016; GO:0035572; GO:0035573; GO:0042054; GO:0071885 2311 XR_006394120.1 41 53 35 89 81 NA NA NA NA NA NA 2312 XM_044318174.1 50 67 25 86 20 Q8L7C8 1.76e-86 Protein REDUCED WALL ACETYLATION 1 (EC 2.3.1.-) Arabidopsis thaliana (Mouse-ear cress) carbohydrate metabolic process [GO:0005975]; plant-type secondary cell wall biogenesis [GO:0009834]; xylan acetylation [GO:1990937]; xylan biosynthetic process [GO:0045492]; xylan metabolic process [GO:0045491]; xyloglucan metabolic process [GO:0010411] GO:0000139; GO:0005794; GO:0005975; GO:0009834; GO:0010411; GO:0016407; GO:0016491; GO:0045491; GO:0045492; GO:1990937 2313 XM_029345104.2 4 0 19 0 0 Q9DBW0 6.64e-157 Cytochrome P450 4V2 (Docosahexaenoic acid omega-hydroxylase CYP4V2) (EC 1.14.14.79) (Long-chain fatty acid omega-monooxygenase) (EC 1.14.14.80) Mus musculus (Mouse) fatty acid omega-oxidation [GO:0010430] GO:0005506; GO:0005789; GO:0010430; GO:0020037; GO:0102033 2314 XM_029335769.2 93 232 0 0 3 Q9JME2 5.91e-50 Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4S-1) (C4ST-1) (C4ST1) Mus musculus (Mouse) apoptotic process [GO:0006915]; carbohydrate biosynthetic process [GO:0016051]; cartilage development [GO:0051216]; chondrocyte development [GO:0002063]; chondroitin sulfate biosynthetic process [GO:0030206]; chondroitin sulfate metabolic process [GO:0030204]; developmental growth [GO:0048589]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; embryonic viscerocranium morphogenesis [GO:0048703]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; polysaccharide localization [GO:0033037]; post-anal tail morphogenesis [GO:0036342]; post-embryonic development [GO:0009791]; proteoglycan biosynthetic process [GO:0030166]; regulation of cell population proliferation [GO:0042127]; respiratory gaseous exchange by respiratory system [GO:0007585]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0000139; GO:0001537; GO:0001701; GO:0002063; GO:0006915; GO:0007179; GO:0007585; GO:0008146; GO:0009791; GO:0016051; GO:0030166; GO:0030204; GO:0030206; GO:0030326; GO:0030512; GO:0033037; GO:0036342; GO:0042127; GO:0042733; GO:0043066; GO:0047756; GO:0048589; GO:0048703; GO:0048704; GO:0050659; GO:0051216 2315 XM_029327165.2 15 6 6 3 6 P32320 1.33e-38 Cytidine deaminase (EC 3.5.4.5) (Cytidine aminohydrolase) Homo sapiens (Human) cell surface receptor signaling pathway [GO:0007166]; cellular response to external biotic stimulus [GO:0071217]; cytidine deamination [GO:0009972]; cytosine metabolic process [GO:0019858]; negative regulation of cell growth [GO:0030308]; negative regulation of nucleotide metabolic process [GO:0045980]; pyrimidine-containing compound salvage [GO:0008655]; response to cycloheximide [GO:0046898]; UMP salvage [GO:0044206] GO:0001882; GO:0004126; GO:0005576; GO:0005829; GO:0007166; GO:0008270; GO:0008655; GO:0009972; GO:0019858; GO:0030308; GO:0034774; GO:0042802; GO:0042803; GO:0044206; GO:0045980; GO:0046898; GO:0047844; GO:0071217; GO:1904724; GO:1904813 2316 XM_044314565.1 204 16 132 130 143 E7FAM5 1.27e-56 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 2317 XM_044319738.1 0 9 0 0 24 NA NA NA NA NA NA 2318 XM_044315632.1 36 10 0 6 34 NA NA NA NA NA NA 2319 XR_006392071.1 31 9 0 4 0 NA NA NA NA NA NA 2320 XM_044306891.1 6 11 12 9 10 NA NA NA NA NA NA 2321 XR_006391350.1 0 8 121 137 306 NA NA NA NA NA NA 2322 XM_044313566.1 106 11 24 27 45 NA NA NA NA NA NA 2323 XM_044329201.1 11 0 6 21 18 Q8CFK2 1.23e-152 Transcription factor IIIB 90 kDa subunit (TFIIIB90) (mTFIIIB90) (B-related factor 1) (BRF-1) Mus musculus (Mouse) DNA-templated transcription initiation [GO:0006352]; positive regulation of transcription by RNA polymerase III [GO:0045945]; regulation of mRNA stability [GO:0043488]; transcription by RNA polymerase III [GO:0006383]; transcription preinitiation complex assembly [GO:0070897] GO:0000126; GO:0000995; GO:0001006; GO:0005634; GO:0006352; GO:0006383; GO:0017025; GO:0043488; GO:0045945; GO:0046872; GO:0070897; GO:0097550 2324 XM_029329847.2 235 137 126 256 240 Q9D0L4 4.41e-175 AarF domain-containing protein kinase 1 (EC 2.7.-.-) Mus musculus (Mouse) lipid homeostasis [GO:0055088]; mitochondrion organization [GO:0007005]; negative regulation of mitochondrial fusion [GO:0010637]; positive regulation of cristae formation [GO:1903852]; protein phosphorylation [GO:0006468] GO:0004674; GO:0005524; GO:0005576; GO:0005739; GO:0005743; GO:0006468; GO:0007005; GO:0010637; GO:0031966; GO:0055088; GO:1903852 2325 XM_044307261.1 6394 8742 5738 3762 5090 Q5RA31 7.58e-29 Mitochondrial import receptor subunit TOM20 homolog (Mitochondrial 20 kDa outer membrane protein) (Outer mitochondrial membrane receptor Tom20) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) protein targeting to mitochondrion [GO:0006626] GO:0005742; GO:0006626; GO:0015450; GO:0044233; GO:0051082; GO:0097225 2326 XR_006393502.1 4 24 4 0 47 NA NA NA NA NA NA 2327 XM_044325263.1 1467 1402 429 952 293 Q8R4E0 1.8e-41 Interferon regulatory factor 2 (IRF-2) Sigmodon hispidus (Hispid cotton rat) NA GO:0000976; GO:0003700; GO:0005634 2328 XR_006393020.1 500 196 531 569 199 NA NA NA NA NA NA 2329 XM_029354616.2 230 759 415 381 619 NA NA NA NA NA NA 2330 XM_044323374.1 147 173 50 80 132 Q4J9D2 2.68e-41 Uncharacterized protein Saci_1252 Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770) NA NA 2331 XM_029346413.2 1744 936 873 1058 1003 NA NA NA NA NA NA 2332 XM_044328484.1 59 211 248 234 64 Q6NU40 0 Chromosome transmission fidelity protein 18 homolog Xenopus laevis (African clawed frog) cell cycle [GO:0007049]; DNA replication [GO:0006260] GO:0003677; GO:0003689; GO:0005524; GO:0005634; GO:0005663; GO:0006260; GO:0007049; GO:0016887 2333 XM_029350861.2 78 27 0 218 106 P52569 2.9e-145 Cationic amino acid transporter 2 (CAT-2) (CAT2) (Low affinity cationic amino acid transporter 2) (Solute carrier family 7 member 2) Homo sapiens (Human) amino acid import across plasma membrane [GO:0089718]; amino acid transport [GO:0006865]; L-alpha-amino acid transmembrane transport [GO:1902475]; L-amino acid transport [GO:0015807]; L-arginine import across plasma membrane [GO:0097638]; L-arginine transmembrane transport [GO:1903826]; L-ornithine transmembrane transport [GO:1903352]; transport across blood-brain barrier [GO:0150104] GO:0000064; GO:0005886; GO:0006865; GO:0015171; GO:0015174; GO:0015179; GO:0015189; GO:0015807; GO:0030054; GO:0061459; GO:0089718; GO:0097638; GO:0150104; GO:1902475; GO:1903352; GO:1903826 2334 XM_044326149.1 4 12 0 0 0 NA NA NA NA NA NA 2335 XM_044324224.1 67 1321 982 1163 484 G3V9H8 2.27e-75 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Rattus norvegicus (Rat) cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0007156; GO:0007158; GO:0007169; GO:0007399; GO:0009410; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030182; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0098797 2336 XM_029353554.2 92 50 56 32 43 NA NA NA NA NA NA 2337 XM_044323637.1 3 0 1 0 63 NA NA NA NA NA NA 2338 XM_044320551.1 0 36 0 64 107 C0H692 3.88e-21 Small cysteine-rich protein 3 (Amil-SCRiP3) (SCRiP3) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0042151; GO:0090729 2339 XM_044307244.1 3 1 1 5 13 NA NA NA NA NA NA 2340 XR_006396875.1 311 51 42 95 214 NA NA NA NA NA NA 2341 XM_029355548.2 53 14 61 0 103 Q6GPP1 1.13e-132 Telomere length regulation protein TEL2 homolog Xenopus laevis (African clawed frog) NA GO:0000781; GO:0005634; GO:0005737; GO:0016020 2342 XR_006392987.1 41 2 25 5 151 NA NA NA NA NA NA 2343 XM_029354175.2 3 0 2 8 8 O35114 1.4e-68 Lysosome membrane protein 2 (85 kDa lysosomal membrane sialoglycoprotein) (LGP85) (Lysosome membrane protein II) (LIMP II) (Scavenger receptor class B member 2) Mus musculus (Mouse) aminophospholipid transport [GO:0015917]; gene expression [GO:0010467]; positive regulation of neuron projection development [GO:0010976]; protein targeting to lysosome [GO:0006622]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular carbohydrate catabolic process [GO:0043471]; regulation of glucosylceramidase activity [GO:1905123]; sensory perception of sound [GO:0007605] GO:0001786; GO:0005044; GO:0005737; GO:0005765; GO:0005886; GO:0006622; GO:0006898; GO:0007605; GO:0010467; GO:0010976; GO:0015485; GO:0015917; GO:0019899; GO:0030666; GO:0031210; GO:0038024; GO:0042803; GO:0043202; GO:0043471; GO:0051087; GO:1905123 2344 XM_044328917.1 130 62 97 56 144 Q7TN88 3.11e-83 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 2345 XM_029333659.2 9 15 65 18 23 A0JPI9 2.82e-49 Leucine-rich repeat-containing protein 74A (Leucine-rich repeat-containing protein 74) Rattus norvegicus (Rat) NA NA 2346 XM_029356105.2 1549 1120 964 1709 1483 Q8BU14 4.66e-39 Translocation protein SEC62 (Translocation protein 1) (TP-1) Mus musculus (Mouse) post-translational protein targeting to endoplasmic reticulum membrane [GO:0006620]; post-translational protein targeting to membrane, translocation [GO:0031204] GO:0005783; GO:0005789; GO:0006620; GO:0016020; GO:0031204 2347 XM_029356105.2 1549 1120 964 1709 1483 Q8BU14 2.34e-21 Translocation protein SEC62 (Translocation protein 1) (TP-1) Mus musculus (Mouse) post-translational protein targeting to endoplasmic reticulum membrane [GO:0006620]; post-translational protein targeting to membrane, translocation [GO:0031204] GO:0005783; GO:0005789; GO:0006620; GO:0016020; GO:0031204 2348 XR_006392153.1 31 0 3 0 57 NA NA NA NA NA NA 2349 XM_044318045.1 22 43 22 41 38 NA NA NA NA NA NA 2350 XM_044329071.1 519 131 614 474 571 Q9VPD3 3.76e-137 Phosphatidylserine synthase (EC 2.7.8.29) Drosophila melanogaster (Fruit fly) phosphatidylserine biosynthetic process [GO:0006659] GO:0005789; GO:0006659; GO:0012505; GO:0016780; GO:0106245; GO:0106258 2351 XM_044316030.1 10 12 1 13 10 NA NA NA NA NA NA 2352 XM_044319331.1 6 5 0 8 3 NA NA NA NA NA NA 2353 XM_044322362.1 3 11 0 0 0 Q96DM1 1.57e-29 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 2354 XM_029351558.2 810 721 716 741 707 Q9JI19 1.06e-84 Acidic fibroblast growth factor intracellular-binding protein (aFGF intracellular-binding protein) (FGF-1 intracellular-binding protein) Mus musculus (Mouse) NA GO:0005634; GO:0012505; GO:0016020; GO:0016607; GO:0017134 2355 XM_044325147.1 0 0 0 0 7 NA NA NA NA NA NA 2356 XR_003822857.1 29 34 56 30 35 NA NA NA NA NA NA 2357 XM_044324879.1 43 8 7 9 15 NA NA NA NA NA NA 2358 XM_044323224.1 0 57 0 118 132 Q9NZ56 1.85e-95 Formin-2 Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hypoxia [GO:0071456]; establishment of meiotic spindle localization [GO:0051295]; formin-nucleated actin cable assembly [GO:0070649]; homologous chromosome movement towards spindle pole in meiosis I anaphase [GO:0051758]; intracellular signal transduction [GO:0035556]; intracellular transport [GO:0046907]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein catabolic process [GO:0042177]; oogenesis [GO:0048477]; polar body extrusion after meiotic divisions [GO:0040038]; positive regulation of double-strand break repair [GO:2000781]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] GO:0003779; GO:0005634; GO:0005730; GO:0005737; GO:0005783; GO:0005789; GO:0005819; GO:0005829; GO:0005886; GO:0005902; GO:0005938; GO:0006974; GO:0015031; GO:0016192; GO:0016477; GO:0030659; GO:0031532; GO:0035556; GO:0040038; GO:0042177; GO:0043066; GO:0046907; GO:0048471; GO:0048477; GO:0051295; GO:0051758; GO:0070649; GO:0071456; GO:2000781 2359 XM_044326086.1 12 0 0 0 13 NA NA NA NA NA NA 2360 XM_029328910.2 750 515 355 421 723 Q9NPF5 8.72e-133 DNA methyltransferase 1-associated protein 1 (DNMAP1) (DNMT1-associated protein 1) Homo sapiens (Human) chromatin remodeling [GO:0006338]; DNA methylation [GO:0006306]; DNA repair [GO:0006281]; histone acetylation [GO:0016573]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of protein import into nucleus [GO:0042307]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of DNA-templated transcription [GO:0006355]; regulation of double-strand break repair [GO:2000779]; response to ethanol [GO:0045471] GO:0000122; GO:0000786; GO:0000812; GO:0003714; GO:0005634; GO:0005654; GO:0005657; GO:0005737; GO:0005829; GO:0006281; GO:0006306; GO:0006338; GO:0006355; GO:0016573; GO:0035267; GO:0042307; GO:0042981; GO:0043967; GO:0043968; GO:0045471; GO:0045892; GO:0045893; GO:0051726; GO:0061629; GO:1905168; GO:2000779 2361 XM_044328643.1 88 0 0 0 0 P46023 2.85e-113 G-protein coupled receptor GRL101 Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004930; GO:0005886 2362 XM_044317248.1 13 1 0 14 13 NA NA NA NA NA NA 2363 XM_029357620.2 120 65 83 0 63 NA NA NA NA NA NA 2364 XM_029357143.2 1888 1222 943 1322 1109 Q8TB22 0 Spermatogenesis-associated protein 20 (Sperm-specific protein 411) (Ssp411) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; cell differentiation [GO:0030154]; spermatogenesis [GO:0007283] GO:0005576; GO:0005975; GO:0007283; GO:0030154 2365 XM_044320997.1 383 197 355 272 348 F1NVK6 9.25e-30 Transmembrane protein 237 Gallus gallus (Chicken) cilium assembly [GO:0060271]; regulation of Wnt signaling pathway [GO:0030111] GO:0016020; GO:0030111; GO:0035869; GO:0060271 2366 XM_029343746.2 0 52 0 13 0 NA NA NA NA NA NA 2367 XM_029349074.2 254 337 71 288 160 A0A0R4IWG9 2.82e-62 Germ cell nuclear acidic protein (Acidic repeat-containing protein) (Germ cell nuclear acidic peptidase) Danio rerio (Zebrafish) (Brachydanio rerio) protein-DNA covalent cross-linking repair [GO:0106300] GO:0005634; GO:0005694; GO:0016605; GO:0106300 2368 XM_044313362.1 0 0 7 25 0 NA NA NA NA NA NA 2369 XM_029329438.2 616 440 336 505 480 Q5XI06 0 Histone acetyltransferase KAT8 (EC 2.3.1.48) (Lysine acetyltransferase 8) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1) (MYST-1) Rattus norvegicus (Rat) chromatin organization [GO:0006325]; histone acetylation [GO:0016573]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; myeloid cell differentiation [GO:0030099]; negative regulation of DNA-templated transcription [GO:0045892]; neurogenesis [GO:0022008]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of autophagy [GO:0010506]; regulation of dosage compensation by inactivation of X chromosome [GO:1900095] GO:0000123; GO:0000776; GO:0003712; GO:0003713; GO:0005634; GO:0006325; GO:0010484; GO:0010485; GO:0010506; GO:0016363; GO:0016407; GO:0016573; GO:0019899; GO:0022008; GO:0030099; GO:0035064; GO:0042393; GO:0043981; GO:0043982; GO:0043984; GO:0043995; GO:0043996; GO:0044545; GO:0045892; GO:0045893; GO:0045944; GO:0046872; GO:0046972; GO:0051571; GO:0061629; GO:0071339; GO:0072487; GO:1900095 2370 XM_029358428.2 336 36 0 79 38 NA NA NA NA NA NA 2371 XM_029338322.2 185 112 60 112 138 P69070 1.53e-56 Histone H2B Salmo trutta (Brown trout) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 2372 XM_044322535.1 1323 1084 715 1372 1109 Q9TT16 0 H(+)/Cl(-) exchange transporter 6 (Chloride channel protein 6) (ClC-6) (Chloride transport protein 6) Oryctolagus cuniculus (Rabbit) chloride transport [GO:0006821] GO:0005247; GO:0005524; GO:0006821; GO:0015297; GO:0031902 2373 XM_044325006.1 1 0 0 10 8 NA NA NA NA NA NA 2374 XM_044310838.1 103 405 216 166 72 Q7RTR2 5.82e-75 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 2375 XM_044310838.1 103 405 216 166 72 Q7RTR2 1.15e-72 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 2376 XM_044310838.1 103 405 216 166 72 Q7RTR2 4.87e-72 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 2377 XM_044310838.1 103 405 216 166 72 Q7RTR2 6.95e-70 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 2378 XM_044310838.1 103 405 216 166 72 Q7RTR2 7.27e-70 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 2379 XM_044310838.1 103 405 216 166 72 Q7RTR2 4.14e-68 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 2380 XM_044310838.1 103 405 216 166 72 Q7RTR2 9.99e-67 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 2381 XM_044310838.1 103 405 216 166 72 Q7RTR2 4.98e-66 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 2382 XM_044310838.1 103 405 216 166 72 Q7RTR2 3.57e-53 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 2383 XR_003828379.2 162 142 105 238 170 NA NA NA NA NA NA 2384 XM_029334574.2 8 0 7 17 14 NA NA NA NA NA NA 2385 XM_044313716.1 16 9 0 0 20 Q9VBW3 1.23e-63 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 2386 XM_029353121.2 6785 4272 2663 5556 3392 Q87PP5 5.52e-99 Glycine betaine/proline/choline/ectoine transporter VP1456 Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) amino acid transport [GO:0006865] GO:0005886; GO:0006865; GO:0022857 2387 XM_029340271.2 40 53 83 133 52 Q5RA50 3.32e-25 Protein FAM124A Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA NA 2388 XM_044323831.1 641 169 78 37 255 C6FG12 7.78e-26 Protein NLRC5 Ictalurus punctatus (Channel catfish) (Silurus punctatus) innate immune response [GO:0045087] GO:0005524; GO:0005737; GO:0045087 2389 XM_029334854.2 11 0 5 0 8 O75899 3.47e-116 Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51) (HG20) Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway [GO:0007186]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; neuron-glial cell signaling [GO:0150099]; synaptic transmission, GABAergic [GO:0051932] GO:0004888; GO:0004965; GO:0005737; GO:0005886; GO:0007186; GO:0007193; GO:0007194; GO:0007214; GO:0007268; GO:0038039; GO:0043005; GO:0045211; GO:0046982; GO:0051932; GO:0150099; GO:1902710; GO:1902712 2390 XM_044307335.1 142 154 168 119 213 NA NA NA NA NA NA 2391 XR_006394569.1 250 116 33 0 92 Q9R1S3 2.23e-27 GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N) Mus musculus (Mouse) GPI anchor biosynthetic process [GO:0006506] GO:0005789; GO:0005829; GO:0005886; GO:0006506; GO:0016780; GO:0051377 2392 XR_006394569.1 250 116 33 0 92 Q9R1S3 2.23e-27 GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N) Mus musculus (Mouse) GPI anchor biosynthetic process [GO:0006506] GO:0005789; GO:0005829; GO:0005886; GO:0006506; GO:0016780; GO:0051377 2393 XM_029356710.2 0 46 0 0 0 Q9DG67 0 DNA repair and recombination protein RAD54B (EC 3.6.4.-) (RAD54 homolog B) Gallus gallus (Chicken) DNA repair [GO:0006281] GO:0003677; GO:0004386; GO:0005524; GO:0005634; GO:0006281; GO:0016787; GO:0140658 2394 XM_044325059.1 22 0 11 5 61 NA NA NA NA NA NA 2395 XM_044312843.1 7 1 0 8 16 Q9D5U8 3.25e-21 Cyclic nucleotide-binding domain-containing protein 2 (Cyclic nucleotide receptor involved in sperm function) Mus musculus (Mouse) spermatogenesis [GO:0007283] GO:0005829; GO:0007283; GO:0030552 2396 XM_029351043.2 2353 1896 942 2254 2363 Q92783 8.67e-114 Signal transducing adapter molecule 1 (STAM-1) Homo sapiens (Human) macroautophagy [GO:0016236]; membrane fission [GO:0090148]; multivesicular body assembly [GO:0036258]; positive regulation of exosomal secretion [GO:1903543]; protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]; regulation of extracellular exosome assembly [GO:1903551]; signal transduction [GO:0007165] GO:0005829; GO:0007165; GO:0016236; GO:0031901; GO:0033565; GO:0035091; GO:0036258; GO:0043130; GO:0043231; GO:0043328; GO:0044389; GO:0090148; GO:1903543; GO:1903551 2397 XM_044325210.1 252 244 219 95 1170 NA NA NA NA NA NA 2398 XM_044321870.1 108 16 78 47 38 Q7Z020 1.56e-87 Transient receptor potential cation channel subfamily A member 1 (dTRPA1) (Ankyrin-like with transmembrane domains protein 1) (dANKTM1) Drosophila melanogaster (Fruit fly) calcium ion transport [GO:0006816]; cation transport [GO:0006812]; cellular response to heat [GO:0034605]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; detection of temperature stimulus involved in thermoception [GO:0050960]; mechanosensory behavior [GO:0007638]; negative phototaxis [GO:0046957]; neuronal signal transduction [GO:0023041]; phototransduction [GO:0007602]; positive regulation of calcium-mediated signaling [GO:0050850]; response to heat [GO:0009408]; response to light stimulus [GO:0009416]; temperature compensation of the circadian clock [GO:0010378]; thermosensory behavior [GO:0040040]; thermotaxis [GO:0043052] GO:0001580; GO:0005261; GO:0005262; GO:0005886; GO:0006812; GO:0006816; GO:0007602; GO:0007638; GO:0009408; GO:0009416; GO:0010378; GO:0015276; GO:0016020; GO:0023041; GO:0034605; GO:0034703; GO:0040040; GO:0043052; GO:0046957; GO:0050850; GO:0050960; GO:0050965; GO:0050968; GO:0097604 2399 XM_029356268.2 219 136 108 268 223 P22045 1.27e-43 9,11-endoperoxide prostaglandin H2 reductase (EC 1.1.1.-) (Prostaglandin F2-alpha synthase) Leishmania major prostaglandin biosynthetic process [GO:0001516] GO:0000166; GO:0001516; GO:0005737; GO:0036130 2400 XM_044328162.1 26 0 5 6 0 NA NA NA NA NA NA 2401 XM_044312066.1 12 2 20 8 26 NA NA NA NA NA NA 2402 XM_044307755.1 65 20 46 79 234 NA NA NA NA NA NA 2403 XM_029355728.2 18319 13793 14291 11607 7303 A1L3F4 1.96e-95 RNA-binding protein MEX3B (RING finger and KH domain-containing protein 3) Xenopus laevis (African clawed frog) NA GO:0000932; GO:0003723; GO:0005634; GO:0046872 2404 XM_029333338.2 28 0 0 0 0 NA NA NA NA NA NA 2405 XM_044307213.1 2874 1308 179 873 353 NA NA NA NA NA NA 2406 XM_029355694.2 56 44 38 72 130 Q24322 3.6e-53 Semaphorin-1A (Semaphorin-I) (Sema I) Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; dendrite morphogenesis [GO:0048813]; motor neuron axon guidance [GO:0008045]; negative chemotaxis [GO:0050919]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of cell size [GO:0045792]; positive regulation of cell migration [GO:0030335]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in regulation of photoreceptor cell axon guidance [GO:2000305]; synapse assembly [GO:0007416]; synaptic target recognition [GO:0008039] GO:0005615; GO:0005886; GO:0007411; GO:0007416; GO:0008039; GO:0008045; GO:0008201; GO:0016020; GO:0016199; GO:0030215; GO:0030335; GO:0045499; GO:0045792; GO:0048813; GO:0048843; GO:0050919; GO:0071526; GO:2000305 2407 XM_029326238.2 1272 805 608 1166 1197 Q5XHA8 0 CTP synthase 1-A (EC 6.3.4.2) (CTP synthetase 1-A) (UTP--ammonia ligase 1-A) Xenopus laevis (African clawed frog) 'de novo' CTP biosynthetic process [GO:0044210]; CTP biosynthetic process [GO:0006241]; glutamine metabolic process [GO:0006541] GO:0003883; GO:0005524; GO:0006241; GO:0006541; GO:0044210 2408 XR_006397949.1 19 15 16 0 19 NA NA NA NA NA NA 2409 XM_044315036.1 13 1 12 0 27 NA NA NA NA NA NA 2410 XM_044328863.1 99 52 74 111 107 NA NA NA NA NA NA 2411 XR_003823186.2 111 31 58 61 263 NA NA NA NA NA NA 2412 XM_029343295.2 2018 1663 1001 1299 1331 Q15329 1.38e-97 Transcription factor E2F5 (E2F-5) Homo sapiens (Human) cell projection organization [GO:0030030]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000785; GO:0000978; GO:0000981; GO:0001216; GO:0001650; GO:0003700; GO:0005654; GO:0005730; GO:0006357; GO:0030030; GO:0043231; GO:0046983; GO:0090575 2413 XM_029343784.2 417 658 287 671 588 NA NA NA NA NA NA 2414 XM_029340324.2 4 0 0 0 24 Q6NS09 1.13e-26 Transmembrane protein 45B Xenopus laevis (African clawed frog) NA GO:0016020 2415 XM_029347869.2 30 46 14 41 47 NA NA NA NA NA NA 2416 XR_006392134.1 113 93 2 112 1 NA NA NA NA NA NA 2417 XR_006395136.1 3 0 7 0 8 NA NA NA NA NA NA 2418 XM_029335437.2 107 53 65 77 80 NA NA NA NA NA NA 2419 XM_044325234.1 961 584 311 0 0 Q9R1D7 0 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) protein transport [GO:0015031]; regulation of ARF protein signal transduction [GO:0032012] GO:0005085; GO:0005793; GO:0005794; GO:0005811; GO:0008289; GO:0015031; GO:0016020; GO:0032012 2420 XM_044325234.1 961 584 311 0 0 Q9R1D7 1.94e-89 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) protein transport [GO:0015031]; regulation of ARF protein signal transduction [GO:0032012] GO:0005085; GO:0005793; GO:0005794; GO:0005811; GO:0008289; GO:0015031; GO:0016020; GO:0032012 2421 XR_006391270.1 53 0 0 0 0 NA NA NA NA NA NA 2422 XM_029344716.2 339 229 213 273 364 NA NA NA NA NA NA 2423 XM_044311015.1 3055 3170 3006 4318 3540 P10079 1.98e-82 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 2424 XM_044311015.1 3055 3170 3006 4318 3540 P10079 5.53e-79 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 2425 XM_044311015.1 3055 3170 3006 4318 3540 P10079 2.17e-62 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 2426 XM_044311015.1 3055 3170 3006 4318 3540 P10079 1.77e-31 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 2427 XM_029354347.2 30 0 0 156 0 Q8C9S4 2.38e-111 Coiled-coil domain-containing protein 186 (Oocyte-testis gene 1 protein) Mus musculus (Mouse) glucose homeostasis [GO:0042593]; insulin secretion involved in cellular response to glucose stimulus [GO:0035773]; response to bacterium [GO:0009617]; vesicle cytoskeletal trafficking [GO:0099518] GO:0005794; GO:0005802; GO:0009617; GO:0031267; GO:0035773; GO:0042593; GO:0099518 2428 XM_044324657.1 199 88 614 334 1265 O15068 2.23e-152 Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2-transforming sequence-like protein) Homo sapiens (Human) intracellular signal transduction [GO:0035556]; positive regulation of Rho protein signal transduction [GO:0035025]; regulation of small GTPase mediated signal transduction [GO:0051056] GO:0005085; GO:0005615; GO:0005737; GO:0005829; GO:0005886; GO:0012505; GO:0019898; GO:0031234; GO:0035025; GO:0035091; GO:0035556; GO:0051056 2429 XM_044326073.1 18 24 107 59 52 Q15818 5.68e-36 Neuronal pentraxin-1 (NP1) (Neuronal pentraxin I) (NP-I) Homo sapiens (Human) axonogenesis involved in innervation [GO:0060385]; cellular response to glucose stimulus [GO:0071333]; cellular response to potassium ion [GO:0035865]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; mitochondrial transport [GO:0006839]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic density assembly [GO:0097107]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962] GO:0005739; GO:0005886; GO:0006839; GO:0007268; GO:0007417; GO:0030133; GO:0035865; GO:0043005; GO:0043083; GO:0043653; GO:0046872; GO:0060385; GO:0071333; GO:0097107; GO:0098962; GO:0098978; GO:0099645 2430 XM_029350804.2 29 7 19 41 37 Q9JLB4 1.54e-35 Cubilin (Intrinsic factor-cobalamin receptor) Mus musculus (Mouse) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006898; GO:0007584; GO:0008203; GO:0009617; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 2431 XM_029350804.2 29 7 19 41 37 Q9JLB4 2.71e-25 Cubilin (Intrinsic factor-cobalamin receptor) Mus musculus (Mouse) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006898; GO:0007584; GO:0008203; GO:0009617; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 2432 XM_029350804.2 29 7 19 41 37 Q9JLB4 4.54e-24 Cubilin (Intrinsic factor-cobalamin receptor) Mus musculus (Mouse) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006898; GO:0007584; GO:0008203; GO:0009617; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 2433 XM_029350804.2 29 7 19 41 37 Q9JLB4 6.51e-24 Cubilin (Intrinsic factor-cobalamin receptor) Mus musculus (Mouse) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006898; GO:0007584; GO:0008203; GO:0009617; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 2434 XM_029350804.2 29 7 19 41 37 Q9JLB4 7.31e-22 Cubilin (Intrinsic factor-cobalamin receptor) Mus musculus (Mouse) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006898; GO:0007584; GO:0008203; GO:0009617; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 2435 XM_029350804.2 29 7 19 41 37 Q9JLB4 1.45e-21 Cubilin (Intrinsic factor-cobalamin receptor) Mus musculus (Mouse) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006898; GO:0007584; GO:0008203; GO:0009617; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 2436 XM_044320746.1 152 175 32 74 121 NA NA NA NA NA NA 2437 XM_044309167.1 0 3 2 9 8 NA NA NA NA NA NA 2438 XM_029332180.2 560 294 358 394 389 NA NA NA NA NA NA 2439 XM_044322543.1 580 435 414 447 779 P54319 0 Phospholipase A-2-activating protein (PLA2P) (PLAP) Rattus norvegicus (Rat) cellular response to lipopolysaccharide [GO:0071222]; inflammatory response [GO:0006954]; macroautophagy [GO:0016236]; negative regulation of protein K63-linked ubiquitination [GO:1900045]; nervous system development [GO:0007399]; positive regulation of dendrite extension [GO:1903861]; positive regulation of neuron migration [GO:2001224]; positive regulation of phospholipase A2 activity [GO:0032430]; positive regulation of synaptic vesicle recycling [GO:1903423]; prostaglandin metabolic process [GO:0006693]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of catalytic activity [GO:0050790]; ubiquitin recycling [GO:0010992]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] GO:0005634; GO:0005737; GO:0006693; GO:0006954; GO:0007399; GO:0010992; GO:0016005; GO:0016236; GO:0032430; GO:0043130; GO:0043161; GO:0043162; GO:0045202; GO:0050790; GO:0070062; GO:0071222; GO:1900045; GO:1903423; GO:1903861; GO:2001224 2440 XM_044314383.1 77 63 93 65 130 NA NA NA NA NA NA 2441 XM_044328042.1 40 20 25 38 48 NA NA NA NA NA NA 2442 XM_029332743.2 11215 10009 6251 8311 5173 NA NA NA NA NA NA 2443 XM_044326364.1 0 17 4 0 4 Q94K49 2.43e-31 Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1 (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) epigenetic regulation of gene expression [GO:0040029] GO:0003682; GO:0004518; GO:0005634; GO:0035098; GO:0035102; GO:0040029; GO:0046872 2444 XM_044313122.1 7 4 2 10 0 NA NA NA NA NA NA 2445 XM_044310759.1 5 0 8 4 36 P13630 2.25e-40 Histone H2A Paracentrotus lividus (Common sea urchin) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 2446 XM_029353944.2 144 110 53 119 290 Q9H0J4 4.79e-42 Glutamine-rich protein 2 Homo sapiens (Human) cell projection assembly [GO:0030031]; flagellated sperm motility [GO:0030317]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059] GO:0005737; GO:0030031; GO:0030317; GO:0031965; GO:0036126; GO:2000059 2447 XM_029335765.2 46 36 52 10 158 Q96P65 6.82e-21 Pyroglutamylated RF-amide peptide receptor (AQ27) (G-protein coupled receptor 103) (Orexigenic neuropeptide QRFP receptor) (SP9155) Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:0016020 2448 XM_044309555.1 0 0 26 0 0 Q921M4 2.5e-55 Golgin subfamily A member 2 (130 kDa cis-Golgi matrix protein) (GM130) Mus musculus (Mouse) asymmetric cell division [GO:0008356]; axonogenesis [GO:0007409]; centrosome cycle [GO:0007098]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi disassembly [GO:0090166]; Golgi localization [GO:0051645]; Golgi organization [GO:0007030]; Golgi ribbon formation [GO:0090161]; meiotic spindle assembly [GO:0090306]; microtubule nucleation [GO:0007020]; mitotic spindle assembly [GO:0090307]; negative regulation of autophagy [GO:0010507]; negative regulation of protein binding [GO:0032091]; positive regulation of axonogenesis [GO:0050772]; positive regulation of protein glycosylation [GO:0060050]; protein glycosylation [GO:0006486]; protein homotetramerization [GO:0051289]; protein transport [GO:0015031]; spindle assembly [GO:0051225] GO:0000137; GO:0000139; GO:0000922; GO:0005737; GO:0005794; GO:0005801; GO:0005874; GO:0006486; GO:0006888; GO:0007020; GO:0007030; GO:0007098; GO:0007409; GO:0008017; GO:0008356; GO:0010507; GO:0015031; GO:0019901; GO:0019905; GO:0030134; GO:0032091; GO:0032580; GO:0032991; GO:0033116; GO:0042802; GO:0043025; GO:0044877; GO:0048471; GO:0050772; GO:0051225; GO:0051289; GO:0051645; GO:0060050; GO:0061676; GO:0072686; GO:0090161; GO:0090166; GO:0090306; GO:0090307 2449 XM_044313190.1 17 42 72 97 0 NA NA NA NA NA NA 2450 XM_029330027.2 0 48 7 0 0 O18276 2.55e-59 Gamma-aminobutyric acid receptor subunit beta (GABA(A) receptor subunit beta) Caenorhabditis elegans chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165] GO:0004890; GO:0005230; GO:0005231; GO:0005254; GO:0005886; GO:0006811; GO:0007165; GO:0007268; GO:0030594; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:1902476; GO:1902711; GO:1904315 2451 XM_029352983.2 1002 1227 1016 1148 1675 NA NA NA NA NA NA 2452 XM_044318207.1 390 339 189 388 532 Q8N157 0 Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1) Homo sapiens (Human) central nervous system development [GO:0007417]; cilium assembly [GO:0060271]; cloaca development [GO:0035844]; heart looping [GO:0001947]; hindbrain development [GO:0030902]; Kupffer's vesicle development [GO:0070121]; left/right axis specification [GO:0070986]; morphogenesis of a polarized epithelium [GO:0001738]; motile cilium assembly [GO:0044458]; negative regulation of apoptotic process [GO:0043066]; otic vesicle development [GO:0071599]; photoreceptor cell outer segment organization [GO:0035845]; positive regulation of polarized epithelial cell differentiation [GO:0030862]; positive regulation of receptor internalization [GO:0002092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; pronephric duct morphogenesis [GO:0039023]; pronephric nephron tubule morphogenesis [GO:0039008]; protein localization [GO:0008104]; regulation of behavior [GO:0050795]; retina layer formation [GO:0010842]; specification of axis polarity [GO:0065001]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vesicle-mediated transport [GO:0016192] GO:0001738; GO:0001947; GO:0002092; GO:0005813; GO:0005814; GO:0005829; GO:0005911; GO:0005912; GO:0005929; GO:0007169; GO:0007417; GO:0008104; GO:0010842; GO:0016192; GO:0030862; GO:0030902; GO:0035844; GO:0035845; GO:0036038; GO:0036064; GO:0039008; GO:0039023; GO:0042802; GO:0043066; GO:0044458; GO:0045944; GO:0050795; GO:0060271; GO:0065001; GO:0070121; GO:0070986; GO:0071599; GO:0097730 2453 XM_029326461.2 698 541 578 648 719 Q9JI70 9.71e-64 Molecular chaperone MKKS (McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin) (Protein Bbs6 homolog) Mus musculus (Mouse) artery smooth muscle contraction [GO:0014824]; brain morphogenesis [GO:0048854]; cartilage development [GO:0051216]; cerebral cortex development [GO:0021987]; chaperone-mediated protein complex assembly [GO:0051131]; cilium assembly [GO:0060271]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; developmental process [GO:0032502]; face development [GO:0060324]; fat cell differentiation [GO:0045444]; gene expression [GO:0010467]; hippocampus development [GO:0021766]; intracellular transport [GO:0046907]; leptin-mediated signaling pathway [GO:0033210]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of appetite by leptin-mediated signaling pathway [GO:0038108]; negative regulation of blood pressure [GO:0045776]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of multicellular organism growth [GO:0040018]; protein folding [GO:0006457]; regulation of cilium beat frequency involved in ciliary motility [GO:0060296]; regulation of stress fiber assembly [GO:0051492]; response to leptin [GO:0044321]; sensory perception of smell [GO:0007608]; social behavior [GO:0035176]; spermatid development [GO:0007286]; striatum development [GO:0021756]; vasodilation [GO:0042311] GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0006457; GO:0007286; GO:0007608; GO:0010467; GO:0010629; GO:0014824; GO:0021756; GO:0021766; GO:0021987; GO:0030837; GO:0031514; GO:0032502; GO:0033210; GO:0034260; GO:0035176; GO:0036064; GO:0038108; GO:0040018; GO:0042311; GO:0044321; GO:0045444; GO:0045494; GO:0045776; GO:0046907; GO:0048854; GO:0050910; GO:0051082; GO:0051131; GO:0051216; GO:0051492; GO:0060271; GO:0060296; GO:0060324; GO:0061629; GO:1902636; GO:1905515 2454 XM_044309766.1 83 95 119 106 109 NA NA NA NA NA NA 2455 XM_029332061.2 299 220 119 256 392 NA NA NA NA NA NA 2456 XM_029346028.2 280 191 139 214 698 NA NA NA NA NA NA 2457 XM_029334848.2 45 0 0 0 3 NA NA NA NA NA NA 2458 XM_029345250.2 396 105 46 70 75 NA NA NA NA NA NA 2459 XM_044323763.1 40 9 85 23 79 NA NA NA NA NA NA 2460 XM_044325885.1 1360 1044 770 1399 633 P29341 0 Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1) Mus musculus (Mouse) CRD-mediated mRNA stabilization [GO:0070934]; mRNA processing [GO:0006397]; negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900152]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cytoplasmic translation [GO:2000767]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; RNA splicing [GO:0008380]; RNA-mediated gene silencing [GO:0031047] GO:0000184; GO:0003723; GO:0003729; GO:0003730; GO:0005634; GO:0005737; GO:0005829; GO:0006397; GO:0008022; GO:0008143; GO:0008266; GO:0008380; GO:0010494; GO:0030027; GO:0030425; GO:0031047; GO:0031252; GO:0036464; GO:0045202; GO:0060213; GO:0070934; GO:0071013; GO:0106002; GO:1900152; GO:1900153; GO:1990124; GO:1990904; GO:2000623; GO:2000767 2461 XM_044325885.1 1360 1044 770 1399 633 P29341 3.52e-41 Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1) Mus musculus (Mouse) CRD-mediated mRNA stabilization [GO:0070934]; mRNA processing [GO:0006397]; negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900152]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cytoplasmic translation [GO:2000767]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; RNA splicing [GO:0008380]; RNA-mediated gene silencing [GO:0031047] GO:0000184; GO:0003723; GO:0003729; GO:0003730; GO:0005634; GO:0005737; GO:0005829; GO:0006397; GO:0008022; GO:0008143; GO:0008266; GO:0008380; GO:0010494; GO:0030027; GO:0030425; GO:0031047; GO:0031252; GO:0036464; GO:0045202; GO:0060213; GO:0070934; GO:0071013; GO:0106002; GO:1900152; GO:1900153; GO:1990124; GO:1990904; GO:2000623; GO:2000767 2462 XM_044327045.1 45 9 130 0 5 A4IGL7 7.78e-87 Peroxidasin (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0005576; GO:0005604; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0031012; GO:0042744; GO:0046872; GO:0051260; GO:0070207; GO:0070831; GO:0071711; GO:0140825 2463 XM_044327780.1 44 63 134 18 74 NA NA NA NA NA NA 2464 XM_029342683.2 2517 2108 1131 2143 1828 Q5R8Z8 8.2e-132 Ras-related protein Rab-14 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) defense response to bacterium [GO:0042742]; endocytic recycling [GO:0032456]; fibroblast growth factor receptor signaling pathway [GO:0008543]; Golgi to endosome transport [GO:0006895]; phagosome maturation [GO:0090382]; protein transport [GO:0015031]; regulation of embryonic development [GO:0045995]; regulation of protein localization [GO:0032880] GO:0000139; GO:0003924; GO:0005525; GO:0005802; GO:0005829; GO:0006895; GO:0008543; GO:0015031; GO:0019003; GO:0031901; GO:0032456; GO:0032880; GO:0042742; GO:0045335; GO:0045995; GO:0055037; GO:0090382 2465 XM_029331825.2 1487 702 622 729 368 NA NA NA NA NA NA 2466 XM_029350920.2 123 13 41 35 102 Q9C8G5 8.58e-54 CSC1-like protein ERD4 (Hyperosmolality-gated Ca2+ permeable channel 3.1) (AtOSCA3.1) (Protein EARLY-RESPONSIVE TO DEHYDRATION STRESS 4) Arabidopsis thaliana (Mouse-ear cress) NA GO:0000325; GO:0003729; GO:0005227; GO:0005634; GO:0005886; GO:0009506; GO:0009941 2467 XM_029358613.2 992 671 626 951 1063 O14744 0 Protein arginine N-methyltransferase 5 (PRMT5) (EC 2.1.1.320) (72 kDa ICln-binding protein) (Histone-arginine N-methyltransferase PRMT5) (Jak-binding protein 1) (Shk1 kinase-binding protein 1 homolog) (SKB1 homolog) (SKB1Hs) [Cleaved into: Protein arginine N-methyltransferase 5, N-terminally processed] Homo sapiens (Human) chromatin organization [GO:0006325]; circadian regulation of gene expression [GO:0032922]; DNA-templated transcription termination [GO:0006353]; endothelial cell activation [GO:0042118]; Golgi ribbon formation [GO:0090161]; histone arginine methylation [GO:0034969]; histone H4-R3 methylation [GO:0043985]; liver regeneration [GO:0097421]; negative regulation of cell differentiation [GO:0045596]; peptidyl-arginine methylation [GO:0018216]; peptidyl-arginine N-methylation [GO:0035246]; positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:1904992]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of oligodendrocyte differentiation [GO:0048714]; regulation of DNA methylation [GO:0044030]; regulation of DNA-templated transcription [GO:0006355]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of mitotic nuclear division [GO:0007088]; regulation of signal transduction by p53 class mediator [GO:1901796]; spliceosomal snRNP assembly [GO:0000387] GO:0000387; GO:0000785; GO:0002039; GO:0003714; GO:0005634; GO:0005654; GO:0005737; GO:0005794; GO:0005829; GO:0006325; GO:0006353; GO:0006355; GO:0007088; GO:0008168; GO:0008327; GO:0008469; GO:0016274; GO:0018216; GO:0032922; GO:0034709; GO:0034969; GO:0035097; GO:0035243; GO:0035246; GO:0042118; GO:0042802; GO:0043021; GO:0043985; GO:0044020; GO:0044030; GO:0045596; GO:0046982; GO:0048026; GO:0048714; GO:0070372; GO:0070888; GO:0090161; GO:0097421; GO:1901796; GO:1904992 2468 XM_044307551.1 17 3 0 0 0 Q9U6Y6 1.01e-106 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 2469 XM_029324955.2 84 40 50 48 63 B3EWZ8 8.97e-27 Ectin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 2470 XM_044321532.1 31 82 5 25 55 NA NA NA NA NA NA 2471 XR_006392462.1 133 151 54 247 166 NA NA NA NA NA NA 2472 XM_044316702.1 27 7 22 25 61 Q5VU97 4.4e-77 VWFA and cache domain-containing protein 1 (Cache domain-containing protein 1) Homo sapiens (Human) NA GO:0005245; GO:0005891 2473 XM_044319551.1 6 2 12 8 15 NA NA NA NA NA NA 2474 XR_006397430.1 31 16 19 47 83 NA NA NA NA NA NA 2475 XM_044323534.1 243 172 68 225 258 NA NA NA NA NA NA 2476 XM_044328305.1 882 720 455 794 604 Q5XJS5 8.88e-103 THO complex subunit 6 homolog (WD repeat-containing protein 58) Danio rerio (Zebrafish) (Brachydanio rerio) apoptotic process [GO:0006915]; mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0000346; GO:0000347; GO:0003723; GO:0006397; GO:0006406; GO:0006915; GO:0008380; GO:0016607 2477 XM_044309453.1 60692 20260 8257 13609 10606 NA NA NA NA NA NA 2478 XM_044318252.1 214 153 294 192 195 P19440 6.26e-137 Glutathione hydrolase 1 proenzyme (EC 3.4.19.13) (Gamma-glutamyltransferase 1) (Gamma-glutamyltranspeptidase 1) (GGT 1) (EC 2.3.2.2) (Leukotriene-C4 hydrolase) (EC 3.4.19.14) (CD antigen CD224) [Cleaved into: Glutathione hydrolase 1 heavy chain; Glutathione hydrolase 1 light chain] Homo sapiens (Human) amino acid metabolic process [GO:0006520]; cysteine biosynthetic process [GO:0019344]; fatty acid metabolic process [GO:0006631]; glutamate metabolic process [GO:0006536]; glutathione biosynthetic process [GO:0006750]; glutathione catabolic process [GO:0006751]; leukotriene D4 biosynthetic process [GO:1901750]; leukotriene metabolic process [GO:0006691]; peptide modification [GO:0031179]; proteolysis [GO:0006508]; regulation of immune system process [GO:0002682]; regulation of inflammatory response [GO:0050727]; spermatogenesis [GO:0007283]; zymogen activation [GO:0031638] GO:0000048; GO:0002682; GO:0002951; GO:0005615; GO:0005886; GO:0006508; GO:0006520; GO:0006536; GO:0006631; GO:0006691; GO:0006750; GO:0006751; GO:0007283; GO:0019344; GO:0031179; GO:0031638; GO:0036374; GO:0050727; GO:0070062; GO:0102953; GO:0103068; GO:1901750 2479 XM_044316658.1 5073 6898 2192 4693 3437 P27075 6.38e-51 60S ribosomal protein L44 (60S ribosomal protein L41) Candida tropicalis (Yeast) response to antibiotic [GO:0046677]; response to cycloheximide [GO:0046898]; translation [GO:0006412] GO:0003735; GO:0005840; GO:0006412; GO:0046677; GO:0046898; GO:1990904 2480 XM_044312927.1 40 24 114 15 219 F8W2M8 2.23e-175 Tripeptidyl-peptidase 1 (TPP-1) (EC 3.4.14.9) (Tripeptidyl aminopeptidase) (Tripeptidyl-peptidase I) (TPP-I) Danio rerio (Zebrafish) (Brachydanio rerio) central nervous system development [GO:0007417]; locomotory behavior [GO:0007626]; neurogenesis [GO:0022008]; proteolysis [GO:0006508] GO:0004175; GO:0004252; GO:0005764; GO:0006508; GO:0007417; GO:0007626; GO:0008240; GO:0022008; GO:0046872 2481 XR_003828489.2 9 8 20 0 0 NA NA NA NA NA NA 2482 XM_029357507.2 326 68 303 403 427 Q91428 5.13e-57 Transcription factor GATA-3 (GATA-binding factor 3) Danio rerio (Zebrafish) (Brachydanio rerio) cardiac muscle tissue regeneration [GO:0061026]; cell fate commitment [GO:0045165]; ectodermal placode development [GO:0071696]; ectodermal placode formation [GO:0060788]; embryonic neurocranium morphogenesis [GO:0048702]; embryonic organ development [GO:0048568]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fin regeneration [GO:0031101]; immune system development [GO:0002520]; negative regulation of transcription by RNA polymerase II [GO:0000122]; otic placode formation [GO:0043049]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of neurogenesis [GO:0050769]; positive regulation of neuron migration [GO:2001224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of epithelial cell differentiation [GO:0030856]; tissue regeneration [GO:0042246]; ventral spinal cord interneuron differentiation [GO:0021514] GO:0000122; GO:0000978; GO:0000981; GO:0002520; GO:0005634; GO:0008270; GO:0008284; GO:0008543; GO:0021514; GO:0030856; GO:0031101; GO:0042246; GO:0043049; GO:0045165; GO:0045944; GO:0048568; GO:0048702; GO:0050769; GO:0060788; GO:0061026; GO:0071696; GO:2001224 2483 XM_044318763.1 154 67 73 118 63 Q766D5 5.52e-26 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Mus musculus (Mouse) chondroitin sulfate biosynthetic process [GO:0030206] GO:0008376; GO:0030206; GO:0032580; GO:0033842; GO:0047238 2484 XM_044325974.1 0 0 5 27 0 NA NA NA NA NA NA 2485 XM_044320491.1 85 2 60 333 26 Q7RTR2 5.2e-44 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 2486 XM_044320491.1 85 2 60 333 26 Q7RTR2 7.69e-35 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 2487 XM_044309895.1 7 0 5 0 5 NA NA NA NA NA NA 2488 XM_044325707.1 1180 373 962 835 1600 Q12789 7.37e-72 General transcription factor 3C polypeptide 1 (TF3C-alpha) (TFIIIC box B-binding subunit) (Transcription factor IIIC 220 kDa subunit) (TFIIIC 220 kDa subunit) (TFIIIC220) (Transcription factor IIIC subunit alpha) Homo sapiens (Human) 5S class rRNA transcription by RNA polymerase III [GO:0042791]; rRNA transcription [GO:0009303]; transcription by RNA polymerase III [GO:0006383]; transcription initiation at RNA polymerase III promoter [GO:0006384]; tRNA transcription [GO:0009304]; tRNA transcription by RNA polymerase III [GO:0042797] GO:0000127; GO:0000995; GO:0003677; GO:0005654; GO:0005730; GO:0006383; GO:0006384; GO:0009303; GO:0009304; GO:0016020; GO:0042791; GO:0042797; GO:1990904 2489 XM_044325707.1 1180 373 962 835 1600 Q12789 5.46e-45 General transcription factor 3C polypeptide 1 (TF3C-alpha) (TFIIIC box B-binding subunit) (Transcription factor IIIC 220 kDa subunit) (TFIIIC 220 kDa subunit) (TFIIIC220) (Transcription factor IIIC subunit alpha) Homo sapiens (Human) 5S class rRNA transcription by RNA polymerase III [GO:0042791]; rRNA transcription [GO:0009303]; transcription by RNA polymerase III [GO:0006383]; transcription initiation at RNA polymerase III promoter [GO:0006384]; tRNA transcription [GO:0009304]; tRNA transcription by RNA polymerase III [GO:0042797] GO:0000127; GO:0000995; GO:0003677; GO:0005654; GO:0005730; GO:0006383; GO:0006384; GO:0009303; GO:0009304; GO:0016020; GO:0042791; GO:0042797; GO:1990904 2490 XM_029352959.2 119 174 120 602 68 Q8VIJ6 1.47e-82 Splicing factor, proline- and glutamine-rich (DNA-binding p52/p100 complex, 100 kDa subunit) (Polypyrimidine tract-binding protein-associated-splicing factor) (PSF) (PTB-associated-splicing factor) Mus musculus (Mouse) activation of innate immune response [GO:0002218]; alternative mRNA splicing, via spliceosome [GO:0000380]; cellular response to DNA damage stimulus [GO:0006974]; chromosome organization [GO:0051276]; dendritic transport of messenger ribonucleoprotein complex [GO:0098963]; double-strand break repair via homologous recombination [GO:0000724]; histone H3 deacetylation [GO:0070932]; innate immune response [GO:0045087]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of sister chromatid cohesion [GO:0045876]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell cycle [GO:0051726]; regulation of circadian rhythm [GO:0042752]; regulation of DNA-templated transcription [GO:0006355]; rhythmic process [GO:0048511] GO:0000122; GO:0000380; GO:0000724; GO:0000785; GO:0000976; GO:0002218; GO:0003677; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0006355; GO:0006974; GO:0016363; GO:0016607; GO:0032839; GO:0042382; GO:0042752; GO:0042754; GO:0042803; GO:0042826; GO:0045087; GO:0045876; GO:0045892; GO:0045944; GO:0048511; GO:0051276; GO:0051726; GO:0070932; GO:0090575; GO:0098963; GO:1902177 2491 XM_044323931.1 45 0 0 30 116 O95263 0 High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B (HsPDE8B) (EC 3.1.4.53) (Cell proliferation-inducing gene 22 protein) Homo sapiens (Human) behavioral fear response [GO:0001662]; cAMP catabolic process [GO:0006198]; negative regulation of steroid hormone biosynthetic process [GO:0090032]; neuromuscular process controlling balance [GO:0050885]; operant conditioning [GO:0035106]; signal transduction [GO:0007165]; visual learning [GO:0008542] GO:0001662; GO:0004114; GO:0004115; GO:0005829; GO:0006198; GO:0007165; GO:0008542; GO:0035106; GO:0046872; GO:0050885; GO:0090032 2492 XM_029344619.2 1415 1250 726 1654 1514 P19891 0 Asparagine synthetase [glutamine-hydrolyzing] (EC 6.3.5.4) (Glutamine-dependent asparagine synthetase) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) cellular response to glucose starvation [GO:0042149]; glutamine metabolic process [GO:0006541]; L-asparagine biosynthetic process [GO:0070981]; negative regulation of apoptotic process [GO:0043066]; positive regulation of mitotic cell cycle [GO:0045931] GO:0004066; GO:0005524; GO:0005829; GO:0006541; GO:0042149; GO:0043066; GO:0045931; GO:0070981 2493 XM_029324489.2 325 360 238 164 118 NA NA NA NA NA NA 2494 XM_029349234.2 283 0 72 0 0 Q53G59 0 Kelch-like protein 12 (CUL3-interacting protein 1) (DKIR homolog) (hDKIR) Homo sapiens (Human) COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; protein monoubiquitination [GO:0006513]; Wnt signaling pathway [GO:0016055] GO:0005829; GO:0006513; GO:0006888; GO:0014029; GO:0014032; GO:0016055; GO:0030127; GO:0030134; GO:0031463; GO:0034451; GO:0042802; GO:0043231; GO:0048208 2495 XM_044324077.1 29 47 33 34 47 NA NA NA NA NA NA 2496 XM_044318451.1 40 40 32 32 72 O70157 5.67e-25 DNA topoisomerase 3-alpha (EC 5.6.2.1) (DNA topoisomerase III alpha) Mus musculus (Mouse) chromosome separation [GO:0051304]; DNA topological change [GO:0006265]; double-strand break repair via homologous recombination [GO:0000724]; mitochondrial DNA metabolic process [GO:0032042]; resolution of recombination intermediates [GO:0071139] GO:0000724; GO:0003697; GO:0003916; GO:0003917; GO:0005634; GO:0005654; GO:0005759; GO:0006265; GO:0008270; GO:0016605; GO:0031422; GO:0032042; GO:0051304; GO:0071139 2497 XM_044318451.1 40 40 32 32 72 O70157 5.67e-25 DNA topoisomerase 3-alpha (EC 5.6.2.1) (DNA topoisomerase III alpha) Mus musculus (Mouse) chromosome separation [GO:0051304]; DNA topological change [GO:0006265]; double-strand break repair via homologous recombination [GO:0000724]; mitochondrial DNA metabolic process [GO:0032042]; resolution of recombination intermediates [GO:0071139] GO:0000724; GO:0003697; GO:0003916; GO:0003917; GO:0005634; GO:0005654; GO:0005759; GO:0006265; GO:0008270; GO:0016605; GO:0031422; GO:0032042; GO:0051304; GO:0071139 2498 XM_044322638.1 563 365 278 522 1004 Q15021 0 Condensin complex subunit 1 (Chromosome condensation-related SMC-associated protein 1) (Chromosome-associated protein D2) (hCAP-D2) (Non-SMC condensin I complex subunit D2) (XCAP-D2 homolog) Homo sapiens (Human) cell division [GO:0051301]; meiotic chromosome condensation [GO:0010032]; mitotic chromosome condensation [GO:0007076]; positive regulation of chromosome condensation [GO:1905821]; positive regulation of chromosome segregation [GO:0051984]; positive regulation of chromosome separation [GO:1905820] GO:0000779; GO:0000793; GO:0000794; GO:0000796; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0007076; GO:0010032; GO:0016020; GO:0042393; GO:0051301; GO:0051984; GO:1905820; GO:1905821 2499 XM_029352427.2 8 0 0 22 13 NA NA NA NA NA NA 2500 XM_029346473.2 166 103 63 85 119 Q54TR1 4.64e-70 Counting factor associated protein D Dictyostelium discoideum (Social amoeba) immune response [GO:0006955]; negative regulation of asexual reproduction [GO:1903665]; positive regulation of chemorepellent activity [GO:1903669]; protein localization to plasma membrane [GO:0072659]; proteolysis involved in protein catabolic process [GO:0051603]; sorocarp morphogenesis [GO:0031288] GO:0004197; GO:0005576; GO:0005615; GO:0005764; GO:0006955; GO:0031288; GO:0031410; GO:0051603; GO:0072659; GO:1903665; GO:1903669 2501 XM_044316511.1 24 3 0 4 10 Q96MB7 2.7e-26 Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease) Homo sapiens (Human) NA GO:0004518; GO:0005634; GO:0005829; GO:0005886; GO:0034451; GO:0046872 2502 XM_029330790.2 475 207 321 496 652 Q9JL70 6.5e-61 Fanconi anemia group A protein homolog (Protein FACA) Mus musculus (Mouse) female gonad development [GO:0008585]; interstrand cross-link repair [GO:0036297]; male gonad development [GO:0008584]; male meiotic nuclear division [GO:0007140]; protein monoubiquitination [GO:0006513]; regulation of CD40 signaling pathway [GO:2000348]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of germ cell proliferation [GO:1905936]; regulation of inflammatory response [GO:0050727]; regulation of regulatory T cell differentiation [GO:0045589] GO:0000785; GO:0005634; GO:0005654; GO:0005737; GO:0006513; GO:0007140; GO:0008584; GO:0008585; GO:0036297; GO:0043240; GO:0045589; GO:0050727; GO:0051090; GO:1905936; GO:2000348 2503 XM_044314195.1 0 1 0 21 6 NA NA NA NA NA NA 2504 XM_029336636.2 994 520 242 500 559 Q86UW9 3.63e-84 Probable E3 ubiquitin-protein ligase DTX2 (EC 2.3.2.27) (Protein deltex-2) (Deltex2) (hDTX2) (RING finger protein 58) (RING-type E3 ubiquitin transferase DTX2) Homo sapiens (Human) Notch signaling pathway [GO:0007219]; protein ubiquitination [GO:0016567] GO:0005654; GO:0005737; GO:0007219; GO:0008270; GO:0016567; GO:0031965; GO:0061630 2505 XM_029336636.2 994 520 242 500 559 Q86UW9 4.53e-25 Probable E3 ubiquitin-protein ligase DTX2 (EC 2.3.2.27) (Protein deltex-2) (Deltex2) (hDTX2) (RING finger protein 58) (RING-type E3 ubiquitin transferase DTX2) Homo sapiens (Human) Notch signaling pathway [GO:0007219]; protein ubiquitination [GO:0016567] GO:0005654; GO:0005737; GO:0007219; GO:0008270; GO:0016567; GO:0031965; GO:0061630 2506 XR_003824025.2 0 0 0 9 0 NA NA NA NA NA NA 2507 XM_029342253.2 934 605 304 556 499 NA NA NA NA NA NA 2508 XM_044325550.1 259 66 163 293 344 Q7TQF2 2.17e-88 F-box only protein 10 Mus musculus (Mouse) apoptotic process [GO:0006915]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0005737; GO:0006511; GO:0006915; GO:0016567; GO:0042981 2509 XM_044325550.1 259 66 163 293 344 Q7TQF2 5.98e-62 F-box only protein 10 Mus musculus (Mouse) apoptotic process [GO:0006915]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0005737; GO:0006511; GO:0006915; GO:0016567; GO:0042981 2510 XM_029349738.2 0 41 0 0 0 Q969X6 9.45e-120 U3 small nucleolar RNA-associated protein 4 homolog (Cirhin) (UTP4 small subunit processome component) Homo sapiens (Human) maturation of SSU-rRNA [GO:0030490]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; regulation of DNA-templated transcription [GO:0006355] GO:0000462; GO:0001650; GO:0003723; GO:0005654; GO:0005694; GO:0005730; GO:0006355; GO:0030490; GO:0030686; GO:0032040; GO:0034455 2511 XM_044307303.1 5930 5580 3153 9466 5115 Q3UFK8 2.44e-69 FERM domain-containing protein 8 (iRhom tail-associated protein) (iTAP) Mus musculus (Mouse) negative regulation of canonical Wnt signaling pathway [GO:0090090]; positive regulation of tumor necrosis factor production [GO:0032760]; protein localization to plasma membrane [GO:0072659] GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0032760; GO:0034451; GO:0072659; GO:0090090 2512 XM_029335383.2 3 6 16 4 23 NA NA NA NA NA NA 2513 XM_044308909.1 3 0 1 0 22 NA NA NA NA NA NA 2514 XR_006395972.1 0 224 239 254 464 Q5AXT5 3.99e-32 ATP-dependent DNA helicase PIF1 (EC 3.6.4.12) (DNA repair and recombination helicase PIF1) Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; mitochondrial genome maintenance [GO:0000002]; telomere maintenance [GO:0000723] GO:0000002; GO:0000723; GO:0003677; GO:0005524; GO:0005634; GO:0005657; GO:0005739; GO:0006260; GO:0006281; GO:0006310; GO:0016887; GO:0032508; GO:0043139 2515 XM_044327910.1 0 0 0 0 48 NA NA NA NA NA NA 2516 XM_029356188.2 4 12 11 0 6 P19019 1.14e-51 Gamma-aminobutyric acid receptor subunit beta-3 (GABA(A) receptor subunit beta-3) Gallus gallus (Chicken) chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid signaling pathway [GO:0007214]; inhibitory synapse assembly [GO:1904862]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165] GO:0004890; GO:0005231; GO:0005886; GO:0007165; GO:0007214; GO:0007268; GO:0022851; GO:0030594; GO:0030659; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:1902476; GO:1902711; GO:1904315; GO:1904862 2517 XM_029328602.2 11 0 0 0 0 Q9FT72 3.11e-21 ATP-dependent DNA helicase Q-like 3 (EC 3.6.4.12) (RecQ-like protein 3) (AtRecQ3) (AtRecQl3) Arabidopsis thaliana (Mouse-ear cress) DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724] GO:0000724; GO:0004386; GO:0005524; GO:0005634; GO:0005694; GO:0005737; GO:0006268; GO:0006281; GO:0006310; GO:0009378; GO:0016887; GO:0032508; GO:0043138; GO:0046872; GO:1990814 2518 XM_029324036.2 578 749 405 609 387 P61214 7.73e-47 ADP-ribosylation factor-like protein 4A Rattus norvegicus (Rat) brown fat cell differentiation [GO:0050873]; intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192] GO:0003924; GO:0005525; GO:0005634; GO:0005730; GO:0005737; GO:0005886; GO:0006886; GO:0016192; GO:0050873 2519 XM_029331849.2 299 237 198 413 424 F1MBP6 0 Kelch-like protein 3 Bos taurus (Bovine) distal tubule morphogenesis [GO:0072156]; gene expression [GO:0010467]; ion homeostasis [GO:0050801]; potassium ion homeostasis [GO:0055075]; protein K48-linked ubiquitination [GO:0070936]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; renal sodium ion absorption [GO:0070294]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0003779; GO:0005829; GO:0005856; GO:0006468; GO:0006511; GO:0010467; GO:0016567; GO:0031463; GO:0050801; GO:0055075; GO:0070294; GO:0070936; GO:0072156; GO:0097602 2520 XM_029328055.2 578 39 214 245 76 NA NA NA NA NA NA 2521 XM_029347363.2 0 0 22 0 29 NA NA NA NA NA NA 2522 XM_044311894.1 18 0 0 28 0 NA NA NA NA NA NA 2523 XR_006396822.1 517 542 321 523 378 Q66JD7 2.13e-21 Acyl-CoA-binding domain-containing protein 6 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0000062; GO:0005737 2524 XM_044318376.1 3 34 49 86 91 NA NA NA NA NA NA 2525 XR_006395918.1 10 0 9 0 0 NA NA NA NA NA NA 2526 XM_029341079.2 796 460 557 349 334 NA NA NA NA NA NA 2527 XR_003827339.2 323 427 167 288 382 NA NA NA NA NA NA 2528 XM_044324099.1 0 0 9 0 1 NA NA NA NA NA NA 2529 XM_029335719.2 22 13 18 12 0 E7F7V7 4.53e-22 Galanin receptor 2b Danio rerio (Zebrafish) (Brachydanio rerio) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; neuropeptide signaling pathway [GO:0007218] GO:0004966; GO:0005886; GO:0007188; GO:0007218; GO:0008528 2530 XR_006397125.1 1 0 9 7 8 NA NA NA NA NA NA 2531 XM_029329476.2 7669 5102 4039 6418 8394 Q5R7A7 0 Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 3) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; protein phosphorylation [GO:0006468] GO:0004674; GO:0005524; GO:0005769; GO:0006468; GO:0035091; GO:0055037; GO:0106310; GO:2001240 2532 XM_044315224.1 0 163 0 0 0 Q567Y6 2.38e-61 Intraflagellar transport protein 22 homolog (Rab-like protein 5) Danio rerio (Zebrafish) (Brachydanio rerio) intracellular protein transport [GO:0006886] GO:0003924; GO:0005525; GO:0006886; GO:0012505; GO:0030992 2533 XR_003825356.2 18 198 82 17 22 NA NA NA NA NA NA 2534 XM_029333138.2 2260 1403 1417 2468 2411 Q811L6 0 Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1) Mus musculus (Mouse) cytoskeleton organization [GO:0007010]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; proteolysis [GO:0006508] GO:0000287; GO:0004222; GO:0004674; GO:0005524; GO:0005737; GO:0006508; GO:0007010; GO:0018105; GO:0035556; GO:0106310 2535 XM_029333138.2 2260 1403 1417 2468 2411 Q811L6 4.19e-25 Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1) Mus musculus (Mouse) cytoskeleton organization [GO:0007010]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; proteolysis [GO:0006508] GO:0000287; GO:0004222; GO:0004674; GO:0005524; GO:0005737; GO:0006508; GO:0007010; GO:0018105; GO:0035556; GO:0106310 2536 XM_029348036.2 0 0 0 7 17 NA NA NA NA NA NA 2537 XM_029348037.2 119 144 199 100 475 Q86WI1 0 Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) Homo sapiens (Human) immune response [GO:0006955]; sensory perception of sound [GO:0007605] GO:0005615; GO:0005829; GO:0006955; GO:0007605; GO:0016020; GO:0032426; GO:0038023; GO:0120234 2538 XM_029337896.2 8296 14289 10809 8847 17567 NA NA NA NA NA NA 2539 XM_029333902.2 0 0 11 0 40 NA NA NA NA NA NA 2540 XR_006397934.1 30 624 197 1102 488 NA NA NA NA NA NA 2541 XR_006396306.1 1005 1074 577 1224 1026 NA NA NA NA NA NA 2542 XM_044308078.1 7673 8613 6004 5430 4512 P62744 4.49e-82 AP-2 complex subunit sigma (Adaptor protein complex AP-2 subunit sigma) (Adaptor-related protein complex 2 subunit sigma) (Clathrin assembly protein 2 sigma small chain) (Clathrin coat assembly protein AP17) (Clathrin coat-associated protein AP17) (Plasma membrane adaptor AP-2 17 kDa protein) (Sigma-adaptin 3b) (Sigma2-adaptin) Rattus norvegicus (Rat) clathrin-dependent endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; synaptic vesicle endocytosis [GO:0048488]; vesicle-mediated transport [GO:0016192] GO:0005886; GO:0006886; GO:0016192; GO:0030122; GO:0035615; GO:0043231; GO:0045202; GO:0048488; GO:0072583; GO:0098794; GO:0098884; GO:0098894; GO:0098978 2543 XM_044312320.1 0 3 0 0 12 NA NA NA NA NA NA 2544 XR_006396506.1 8 12 17 11 46 NA NA NA NA NA NA 2545 XR_006396042.1 0 0 2 0 16 NA NA NA NA NA NA 2546 XM_044310855.1 0 3 0 3 68 Q7RTR2 4.53e-78 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 2547 XM_044310855.1 0 3 0 3 68 Q7RTR2 3.04e-74 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 2548 XM_044310855.1 0 3 0 3 68 Q7RTR2 2.19e-30 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 2549 XM_044320590.1 169 355 34 642 330 NA NA NA NA NA NA 2550 XM_029358126.2 167 0 0 0 38 NA NA NA NA NA NA 2551 XM_044311999.1 153 29 75 98 76 C3VPR6 1.16e-26 Protein NLRC5 Mus musculus (Mouse) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of type II interferon-mediated signaling pathway [GO:0060335]; regulation of kinase activity [GO:0043549]; response to bacterium [GO:0009617] GO:0000978; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0009617; GO:0032088; GO:0035556; GO:0043549; GO:0045087; GO:0045345; GO:0045944; GO:0051607; GO:0060335; GO:0060339; GO:0060340 2552 XR_006397572.1 217 269 292 442 311 NA NA NA NA NA NA 2553 XM_044315260.1 471 412 222 292 345 P11834 1.91e-21 Opioid-binding protein/cell adhesion molecule (OBCAM) (OPCML) (Opioid-binding cell adhesion molecule) Bos taurus (Bovine) cell adhesion [GO:0007155] GO:0005886; GO:0007155 2554 XM_044315178.1 203 170 64 338 300 NA NA NA NA NA NA 2555 XR_003824502.2 4340 4484 3469 4152 2050 NA NA NA NA NA NA 2556 XM_029357279.2 789 748 490 740 974 NA NA NA NA NA NA 2557 XM_044316245.1 1220 498 890 1725 1604 Q6P1C6 1.62e-117 Leucine-rich repeats and immunoglobulin-like domains protein 3 (LIG-3) Mus musculus (Mouse) otolith morphogenesis [GO:0032474] GO:0005886; GO:0030659; GO:0032474 2558 XM_044326588.1 1360 969 1209 2473 2101 Q91285 5.69e-77 Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (PFR1) Pleurodeles waltl (Iberian ribbed newt) positive regulation of cell population proliferation [GO:0008284] GO:0005007; GO:0005524; GO:0005634; GO:0005829; GO:0005886; GO:0008284; GO:0031410 2559 XM_029334484.2 3876 6221 2696 4003 2221 O73817 1.11e-123 Proteasome subunit beta type-3 (Proteasome chain 13) (Proteasome component C10-II) (Proteasome theta chain) Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] GO:0005634; GO:0005737; GO:0005839; GO:0019774; GO:0043161 2560 XM_044321189.1 28 0 0 38 32 NA NA NA NA NA NA 2561 XM_044307116.1 0 1 210 407 32 Q9U6Y6 5.78e-106 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 2562 XM_029326982.2 35 64 14 18 0 Q9UJX0 1.19e-122 Oxidative stress-induced growth inhibitor 1 (Bone marrow stromal cell-derived growth inhibitor) (BMSC-derived growth inhibitor) (Ovary, kidney and liver protein 38) (huOKL38) (Pregnancy-induced growth inhibitor OKL38) Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of cell growth [GO:0030308]; regulation of apoptotic process [GO:0042981]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127] GO:0008083; GO:0030154; GO:0030308; GO:0030334; GO:0042127; GO:0042981 2563 XM_029337280.2 453 311 154 325 251 NA NA NA NA NA NA 2564 XM_029350545.2 1144 522 514 796 830 NA NA NA NA NA NA 2565 XM_044321451.1 84 20 74 28 15 O43900 3.54e-128 Prickle planar cell polarity protein 3 (LIM domain only protein 6) (LMO-6) (Prickle-like protein 3) (Pk3) (Triple LIM domain protein 6) Homo sapiens (Human) cell projection organization [GO:0030030] GO:0005739; GO:0005886; GO:0008270; GO:0030030 2566 XM_044310502.1 2 0 1 21 23 NA NA NA NA NA NA 2567 XR_006395106.1 0 0 7 3 0 NA NA NA NA NA NA 2568 XR_003822919.2 990 1113 295 3352 724 NA NA NA NA NA NA 2569 XM_044320672.1 12 3 49 12 70 Q96RW7 7.91e-102 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 2570 XM_044320672.1 12 3 49 12 70 Q96RW7 1.04e-90 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 2571 XM_044320672.1 12 3 49 12 70 Q96RW7 8.31e-90 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 2572 XM_044320672.1 12 3 49 12 70 Q96RW7 1.91e-88 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 2573 XM_044320672.1 12 3 49 12 70 Q96RW7 9.87e-87 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 2574 XM_044320672.1 12 3 49 12 70 Q96RW7 1.27e-86 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 2575 XM_044320672.1 12 3 49 12 70 Q96RW7 2.85e-85 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 2576 XM_044320672.1 12 3 49 12 70 Q96RW7 1.97e-84 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 2577 XM_044320672.1 12 3 49 12 70 Q96RW7 6e-84 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 2578 XM_044320672.1 12 3 49 12 70 Q96RW7 1.29e-83 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 2579 XM_044320672.1 12 3 49 12 70 Q96RW7 3.76e-81 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 2580 XM_044320672.1 12 3 49 12 70 Q96RW7 3.6e-80 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 2581 XM_044320672.1 12 3 49 12 70 Q96RW7 5.81e-79 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 2582 XM_044320672.1 12 3 49 12 70 Q96RW7 4.12e-78 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 2583 XM_044320672.1 12 3 49 12 70 Q96RW7 1.54e-75 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 2584 XM_029338391.2 0 0 0 0 26 NA NA NA NA NA NA 2585 XR_006394845.1 39 8 17 10 48 NA NA NA NA NA NA 2586 XM_044308114.1 35 37 124 73 0 NA NA NA NA NA NA 2587 XM_044316534.1 1223 730 668 1385 1254 Q80ZJ6 1.54e-108 Protein zer-1 homolog (Zyg-11 homolog B-like protein) Mus musculus (Mouse) positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515] GO:0006515; GO:0031462; GO:0032436 2588 XM_029335948.2 218 142 291 371 0 Q12767 3.25e-139 Transmembrane protein 94 Homo sapiens (Human) NA GO:0016020 2589 XR_006394029.1 14 0 0 0 0 NA NA NA NA NA NA 2590 XR_006392016.1 99 16 39 19 12 NA NA NA NA NA NA 2591 XR_006394052.1 7 1 8 0 0 NA NA NA NA NA NA 2592 XM_044322665.1 1 0 20 0 3 NA NA NA NA NA NA 2593 XM_029348481.2 64 20 34 116 72 NA NA NA NA NA NA 2594 XR_006396941.1 134 87 34 44 35 NA NA NA NA NA NA 2595 XM_029331419.2 251 116 112 237 118 Q91YI6 1.43e-43 Poly(A) RNA polymerase GLD2 (mGLD-2) (EC 2.7.7.19) (PAP-associated domain-containing protein 4) (Terminal nucleotidyltransferase 2) Mus musculus (Mouse) dark adaptation [GO:1990603]; hematopoietic progenitor cell differentiation [GO:0002244]; hippocampus development [GO:0021766]; histone mRNA catabolic process [GO:0071044]; mRNA polyadenylation [GO:0006378]; negative regulation of miRNA catabolic process [GO:2000626]; neuron differentiation [GO:0030182]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; regulation of translation at postsynapse [GO:0140245]; retina development in camera-type eye [GO:0060041]; RNA 3'-end processing [GO:0031123]; RNA polyadenylation [GO:0043631]; RNA polyadenylation at postsynapse [GO:0140235]; RNA stabilization [GO:0043489] GO:0002244; GO:0004652; GO:0005524; GO:0005634; GO:0005829; GO:0006378; GO:0016779; GO:0021766; GO:0030182; GO:0031123; GO:0034062; GO:0043489; GO:0043631; GO:0045182; GO:0046872; GO:0060041; GO:0070566; GO:0071044; GO:0098794; GO:0098978; GO:0099170; GO:0140235; GO:0140240; GO:0140245; GO:1990603; GO:2000626 2596 XM_029356519.2 320 192 257 546 746 NA NA NA NA NA NA 2597 XM_044326129.1 32 0 0 0 0 NA NA NA NA NA NA 2598 XR_006396153.1 173 35 347 55 624 NA NA NA NA NA NA 2599 XM_044326939.1 0 55 0 139 0 NA NA NA NA NA NA 2600 XM_029352941.2 32 0 51 11 175 Q13443 1.17e-67 Disintegrin and metalloproteinase domain-containing protein 9 (ADAM 9) (EC 3.4.24.-) (Cellular disintegrin-related protein) (Meltrin-gamma) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) Homo sapiens (Human) amyloid precursor protein catabolic process [GO:0042987]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell migration [GO:0016477]; cell-cell adhesion mediated by integrin [GO:0033631]; cell-matrix adhesion [GO:0007160]; cellular response to lipopolysaccharide [GO:0071222]; integrin-mediated signaling pathway [GO:0007229]; keratinocyte differentiation [GO:0030216]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; monocyte activation [GO:0042117]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of macrophage fusion [GO:0034241]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of protein secretion [GO:0050714]; protein processing [GO:0016485]; response to calcium ion [GO:0051592]; response to glucocorticoid [GO:0051384]; response to hydrogen peroxide [GO:0042542]; response to manganese ion [GO:0010042]; response to tumor necrosis factor [GO:0034612]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0004222; GO:0005080; GO:0005178; GO:0005518; GO:0005615; GO:0005925; GO:0006509; GO:0007155; GO:0007160; GO:0007179; GO:0007229; GO:0008237; GO:0009897; GO:0009986; GO:0010042; GO:0016477; GO:0016485; GO:0017124; GO:0030216; GO:0030335; GO:0031293; GO:0033627; GO:0033630; GO:0033631; GO:0034241; GO:0034612; GO:0042117; GO:0042542; GO:0042987; GO:0043236; GO:0043406; GO:0046872; GO:0050714; GO:0051044; GO:0051384; GO:0051549; GO:0051592; GO:0070062; GO:0071222; GO:1902945 2601 XM_044314204.1 396 606 330 861 1188 Q96AY4 2.92e-97 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2602 XM_044314204.1 396 606 330 861 1188 Q96AY4 4.47e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2603 XM_044314204.1 396 606 330 861 1188 Q96AY4 6.02e-89 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2604 XM_044314204.1 396 606 330 861 1188 Q96AY4 7.4e-89 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2605 XM_044314204.1 396 606 330 861 1188 Q96AY4 1.83e-87 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2606 XM_044314204.1 396 606 330 861 1188 Q96AY4 1.8e-86 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2607 XM_044314204.1 396 606 330 861 1188 Q96AY4 6.95e-84 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2608 XM_044314204.1 396 606 330 861 1188 Q96AY4 2.32e-76 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2609 XM_044314204.1 396 606 330 861 1188 Q96AY4 3.45e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2610 XM_044314204.1 396 606 330 861 1188 Q96AY4 5.92e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2611 XM_029342748.2 186 111 108 148 206 P13994 3.83e-108 Probable splicing factor YJU2B (Coiled-coil domain-containing protein 130) Homo sapiens (Human) mRNA splicing, via spliceosome [GO:0000398]; response to virus [GO:0009615]; RNA splicing [GO:0008380] GO:0000398; GO:0005684; GO:0008380; GO:0009615; GO:0071014 2612 XM_044326705.1 277 227 3 146 133 NA NA NA NA NA NA 2613 XM_044309238.1 0 9 0 0 0 NA NA NA NA NA NA 2614 XM_029324698.2 302 202 158 188 181 B5X2B8 5.69e-48 GTPase Era, mitochondrial (ERA-like protein 1) Salmo salar (Atlantic salmon) ribosomal small subunit assembly [GO:0000028] GO:0000028; GO:0005525; GO:0005743; GO:0005759; GO:0019843; GO:0043024 2615 XR_003822800.2 35 37 16 7 35 NA NA NA NA NA NA 2616 XM_044308929.1 0 0 11 15 10 Q6AZB8 8.81e-47 Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0004518; GO:0005634; GO:0005737; GO:0046872 2617 XM_044308194.1 452 1 459 188 855 Q9V9A7 8.79e-164 Probable methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCase subunit beta) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 2) (3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta) Drosophila melanogaster (Fruit fly) coenzyme A metabolic process [GO:0015936]; leucine catabolic process [GO:0006552]; regulation of eclosion [GO:0007563] GO:0004485; GO:0005524; GO:0005739; GO:0005759; GO:0006552; GO:0007563; GO:0015936; GO:1905202 2618 XR_006392573.1 6 3 0 3 0 Q8CJH3 1.81e-56 Plexin-B1 Mus musculus (Mouse) inhibitory synapse assembly [GO:1904862]; negative regulation of cell adhesion [GO:0007162]; negative regulation of osteoblast proliferation [GO:0033689]; neuron projection morphogenesis [GO:0048812]; ossification involved in bone maturation [GO:0043931]; positive regulation of axonogenesis [GO:0050772]; positive regulation of GTPase activity [GO:0043547]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of cytoskeleton organization [GO:0051493]; regulation of GTPase activity [GO:0043087]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis [GO:1900220] GO:0002116; GO:0005886; GO:0007162; GO:0008360; GO:0014068; GO:0017154; GO:0030334; GO:0032794; GO:0033689; GO:0043087; GO:0043547; GO:0043931; GO:0048812; GO:0050772; GO:0051493; GO:0071526; GO:1900220; GO:1902287; GO:1904862 2619 XR_006392573.1 6 3 0 3 0 Q8CJH3 1.81e-56 Plexin-B1 Mus musculus (Mouse) inhibitory synapse assembly [GO:1904862]; negative regulation of cell adhesion [GO:0007162]; negative regulation of osteoblast proliferation [GO:0033689]; neuron projection morphogenesis [GO:0048812]; ossification involved in bone maturation [GO:0043931]; positive regulation of axonogenesis [GO:0050772]; positive regulation of GTPase activity [GO:0043547]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of cytoskeleton organization [GO:0051493]; regulation of GTPase activity [GO:0043087]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis [GO:1900220] GO:0002116; GO:0005886; GO:0007162; GO:0008360; GO:0014068; GO:0017154; GO:0030334; GO:0032794; GO:0033689; GO:0043087; GO:0043547; GO:0043931; GO:0048812; GO:0050772; GO:0051493; GO:0071526; GO:1900220; GO:1902287; GO:1904862 2620 XR_006392573.1 6 3 0 3 0 Q8CJH3 1.81e-56 Plexin-B1 Mus musculus (Mouse) inhibitory synapse assembly [GO:1904862]; negative regulation of cell adhesion [GO:0007162]; negative regulation of osteoblast proliferation [GO:0033689]; neuron projection morphogenesis [GO:0048812]; ossification involved in bone maturation [GO:0043931]; positive regulation of axonogenesis [GO:0050772]; positive regulation of GTPase activity [GO:0043547]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of cytoskeleton organization [GO:0051493]; regulation of GTPase activity [GO:0043087]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis [GO:1900220] GO:0002116; GO:0005886; GO:0007162; GO:0008360; GO:0014068; GO:0017154; GO:0030334; GO:0032794; GO:0033689; GO:0043087; GO:0043547; GO:0043931; GO:0048812; GO:0050772; GO:0051493; GO:0071526; GO:1900220; GO:1902287; GO:1904862 2621 XR_006392573.1 6 3 0 3 0 Q8CJH3 1.81e-56 Plexin-B1 Mus musculus (Mouse) inhibitory synapse assembly [GO:1904862]; negative regulation of cell adhesion [GO:0007162]; negative regulation of osteoblast proliferation [GO:0033689]; neuron projection morphogenesis [GO:0048812]; ossification involved in bone maturation [GO:0043931]; positive regulation of axonogenesis [GO:0050772]; positive regulation of GTPase activity [GO:0043547]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of cytoskeleton organization [GO:0051493]; regulation of GTPase activity [GO:0043087]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis [GO:1900220] GO:0002116; GO:0005886; GO:0007162; GO:0008360; GO:0014068; GO:0017154; GO:0030334; GO:0032794; GO:0033689; GO:0043087; GO:0043547; GO:0043931; GO:0048812; GO:0050772; GO:0051493; GO:0071526; GO:1900220; GO:1902287; GO:1904862 2622 XM_029333007.2 2 15 7 12 0 NA NA NA NA NA NA 2623 XM_044316901.1 12 0 23 2 35 NA NA NA NA NA NA 2624 XM_029358589.2 3063 2195 1647 2926 2507 Q8BGQ7 0 Alanine--tRNA ligase, cytoplasmic (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS) (Protein sticky) (Sti) Mus musculus (Mouse) alanyl-tRNA aminoacylation [GO:0006419]; cerebellar Purkinje cell layer development [GO:0021680]; negative regulation of neuron apoptotic process [GO:0043524]; neuromuscular process [GO:0050905]; neuromuscular process controlling balance [GO:0050885]; neuron apoptotic process [GO:0051402]; regulation of cytoplasmic translational fidelity [GO:0140018]; tRNA modification [GO:0006400] GO:0000049; GO:0002161; GO:0002196; GO:0004813; GO:0005524; GO:0005737; GO:0005739; GO:0005829; GO:0006400; GO:0006419; GO:0008270; GO:0016597; GO:0021680; GO:0043524; GO:0045182; GO:0050885; GO:0050905; GO:0051402; GO:0140018 2625 XM_044326589.1 92 40 35 138 89 Q91285 5.78e-77 Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (PFR1) Pleurodeles waltl (Iberian ribbed newt) positive regulation of cell population proliferation [GO:0008284] GO:0005007; GO:0005524; GO:0005634; GO:0005829; GO:0005886; GO:0008284; GO:0031410 2626 XM_029350222.2 601 432 291 923 515 Q9R0Z9 1.12e-160 Rho GTPase-activating protein 7 (Deleted in liver cancer 1 protein homolog) (DLC-1) (Rho-type GTPase-activating protein 7) (START domain-containing protein 12) (StARD12) (StAR-related lipid transfer protein 12) Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of phospholipase C activity [GO:0007202]; apoptotic process [GO:0006915]; cytoskeleton organization [GO:0007010]; focal adhesion assembly [GO:0048041]; forebrain development [GO:0030900]; heart morphogenesis [GO:0003007]; hindbrain morphogenesis [GO:0021575]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of stress fiber assembly [GO:0051497]; neural tube closure [GO:0001843]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; regulation of Rho protein signal transduction [GO:0035023]; signal transduction [GO:0007165] GO:0001725; GO:0001843; GO:0003007; GO:0005096; GO:0005634; GO:0005737; GO:0005829; GO:0005884; GO:0005901; GO:0005925; GO:0006915; GO:0006919; GO:0007010; GO:0007165; GO:0007202; GO:0008285; GO:0008289; GO:0008360; GO:0017166; GO:0021575; GO:0030036; GO:0030336; GO:0030864; GO:0030900; GO:0032587; GO:0032956; GO:0035023; GO:0035024; GO:0035307; GO:0042169; GO:0043274; GO:0045121; GO:0048041; GO:0051497; GO:0051895; GO:1900119 2627 XM_029350222.2 601 432 291 923 515 Q9R0Z9 4.06e-24 Rho GTPase-activating protein 7 (Deleted in liver cancer 1 protein homolog) (DLC-1) (Rho-type GTPase-activating protein 7) (START domain-containing protein 12) (StARD12) (StAR-related lipid transfer protein 12) Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of phospholipase C activity [GO:0007202]; apoptotic process [GO:0006915]; cytoskeleton organization [GO:0007010]; focal adhesion assembly [GO:0048041]; forebrain development [GO:0030900]; heart morphogenesis [GO:0003007]; hindbrain morphogenesis [GO:0021575]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of stress fiber assembly [GO:0051497]; neural tube closure [GO:0001843]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; regulation of Rho protein signal transduction [GO:0035023]; signal transduction [GO:0007165] GO:0001725; GO:0001843; GO:0003007; GO:0005096; GO:0005634; GO:0005737; GO:0005829; GO:0005884; GO:0005901; GO:0005925; GO:0006915; GO:0006919; GO:0007010; GO:0007165; GO:0007202; GO:0008285; GO:0008289; GO:0008360; GO:0017166; GO:0021575; GO:0030036; GO:0030336; GO:0030864; GO:0030900; GO:0032587; GO:0032956; GO:0035023; GO:0035024; GO:0035307; GO:0042169; GO:0043274; GO:0045121; GO:0048041; GO:0051497; GO:0051895; GO:1900119 2628 XM_044328463.1 745 325 286 434 527 A6NHR9 0 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 (SMC hinge domain-containing protein 1) (EC 3.6.1.-) Homo sapiens (Human) chromosome organization [GO:0051276]; dosage compensation by inactivation of X chromosome [GO:0009048]; double-strand break repair [GO:0006302]; inactivation of X chromosome by heterochromatin formation [GO:0060820]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; nose development [GO:0043584]; positive regulation of DNA repair [GO:0045739]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034] GO:0001740; GO:0003677; GO:0005524; GO:0006302; GO:0009048; GO:0016887; GO:0035861; GO:0042803; GO:0043584; GO:0045739; GO:0051276; GO:0060820; GO:2000042; GO:2001034 2629 XM_029356936.2 2275 1168 852 2294 2175 P51650 0 Succinate-semialdehyde dehydrogenase, mitochondrial (SSADH) (EC 1.2.1.24) (Aldehyde dehydrogenase family 5 member A1) (NAD(+)-dependent succinic semialdehyde dehydrogenase) Rattus norvegicus (Rat) central nervous system development [GO:0007417]; gamma-aminobutyric acid catabolic process [GO:0009450]; gamma-aminobutyric acid metabolic process [GO:0009448]; glutamate metabolic process [GO:0006536]; neurotransmitter catabolic process [GO:0042135]; nitrogen compound metabolic process [GO:0006807]; post-embryonic development [GO:0009791]; succinate metabolic process [GO:0006105] GO:0004777; GO:0005739; GO:0006105; GO:0006536; GO:0006807; GO:0007417; GO:0009448; GO:0009450; GO:0009791; GO:0031406; GO:0042135; GO:0042802; GO:0051287 2630 XR_006392211.1 0 0 0 0 26 NA NA NA NA NA NA 2631 XM_044312238.1 35 9 33 16 47 NA NA NA NA NA NA 2632 XM_029332628.2 0 148 18 177 163 Q8IUR6 2.45e-34 CREB3 regulatory factor (Luman recruitment factor) (LRF) Homo sapiens (Human) negative regulation of endoplasmic reticulum unfolded protein response [GO:1900102]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of intracellular transport [GO:0032388]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein transport [GO:0051222]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; response to endoplasmic reticulum stress [GO:0034976]; response to unfolded protein [GO:0006986] GO:0000122; GO:0000977; GO:0000981; GO:0001228; GO:0005634; GO:0005654; GO:0005737; GO:0006357; GO:0006986; GO:0016604; GO:0032388; GO:0034976; GO:0045732; GO:0045944; GO:0051222; GO:1900102 2633 XR_006394835.1 134 153 130 277 128 NA NA NA NA NA NA 2634 XM_029348677.2 49 65 31 155 92 NA NA NA NA NA NA 2635 XM_029351965.2 18762 14883 18115 13884 9587 NA NA NA NA NA NA 2636 XM_044312227.1 30 6 94 14 132 NA NA NA NA NA NA 2637 XM_029350454.2 56 78 59 85 42 NA NA NA NA NA NA 2638 XM_044322440.1 219 123 41 92 80 Q6DFA8 4.89e-46 Poly(A) RNA polymerase GLD2-B (xGLD-2) (EC 2.7.7.19) (PAP-associated domain-containing protein 4-B) Xenopus laevis (African clawed frog) mRNA processing [GO:0006397]; negative regulation of miRNA catabolic process [GO:2000626]; oogenesis [GO:0048477]; RNA stabilization [GO:0043489] GO:0004652; GO:0005524; GO:0005737; GO:0006397; GO:0034062; GO:0043489; GO:0046872; GO:0048477; GO:0070566; GO:2000626 2639 XM_029329601.2 257 229 147 266 389 Q969V5 5.95e-63 Mitochondrial ubiquitin ligase activator of NFKB 1 (EC 2.3.2.27) (E3 SUMO-protein ligase MUL1) (E3 ubiquitin-protein ligase MUL1) (Growth inhibition and death E3 ligase) (Mitochondrial-anchored protein ligase) (Protein Hades) (Putative NF-kappa-B-activating protein 266) (RING finger protein 218) (RING-type E3 ubiquitin transferase NFKB 1) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cellular response to exogenous dsRNA [GO:0071360]; mitochondrial fission [GO:0000266]; mitochondrion localization [GO:0051646]; negative regulation of cell growth [GO:0030308]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of defense response to virus by host [GO:0050689]; negative regulation of innate immune response [GO:0045824]; negative regulation of mitochondrial fusion [GO:0010637]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of dendrite extension [GO:1903861]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of protein sumoylation [GO:0033235]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901028]; regulation of mitochondrion organization [GO:0010821] GO:0000209; GO:0000266; GO:0002039; GO:0004842; GO:0005739; GO:0005741; GO:0005777; GO:0006915; GO:0006919; GO:0010637; GO:0010821; GO:0016020; GO:0016567; GO:0019789; GO:0030308; GO:0030424; GO:0031625; GO:0031648; GO:0033235; GO:0042802; GO:0043025; GO:0043123; GO:0045824; GO:0046872; GO:0050689; GO:0050821; GO:0051646; GO:0051881; GO:0051898; GO:0060339; GO:0061630; GO:0071360; GO:0071650; GO:0090141; GO:1901028; GO:1903861; GO:1904925 2640 XM_044323024.1 780 0 14 12 0 P02466 4.31e-46 Collagen alpha-2(I) chain (Alpha-2 type I collagen) Rattus norvegicus (Rat) blood vessel development [GO:0001568]; bone mineralization [GO:0030282]; cellular response to amino acid stimulus [GO:0071230]; cellular response to organic substance [GO:0071310]; cellular response to retinoic acid [GO:0071300]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; extracellular matrix assembly [GO:0085029]; extracellular matrix organization [GO:0030198]; protein heterotrimerization [GO:0070208]; regulation of blood pressure [GO:0008217]; response to norepinephrine [GO:0071873]; Rho protein signal transduction [GO:0007266]; skeletal system development [GO:0001501]; skin morphogenesis [GO:0043589]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001501; GO:0001568; GO:0002020; GO:0005201; GO:0005576; GO:0005581; GO:0005584; GO:0005615; GO:0007179; GO:0007266; GO:0008217; GO:0030198; GO:0030199; GO:0030282; GO:0030674; GO:0031012; GO:0032963; GO:0042802; GO:0043589; GO:0046332; GO:0046872; GO:0048407; GO:0062023; GO:0070208; GO:0071230; GO:0071300; GO:0071310; GO:0071873; GO:0085029; GO:0097067 2641 XM_044328306.1 202 484 139 908 696 NA NA NA NA NA NA 2642 XM_044309972.1 67 22 36 15 55 NA NA NA NA NA NA 2643 XM_029329437.2 1183 1295 227 2195 283 NA NA NA NA NA NA 2644 XM_029329815.2 671 268 234 385 1288 Q9EQJ0 2e-161 Two pore calcium channel protein 1 (Voltage-dependent calcium channel protein TPC1) Mus musculus (Mouse) endocytosis involved in viral entry into host cell [GO:0075509]; positive regulation of autophagy [GO:0010508]; regulation of ion transmembrane transport [GO:0034765]; sodium ion transmembrane transport [GO:0035725] GO:0005244; GO:0005248; GO:0005765; GO:0010008; GO:0010508; GO:0015280; GO:0016020; GO:0019905; GO:0031901; GO:0034765; GO:0035725; GO:0036019; GO:0042802; GO:0042803; GO:0055038; GO:0072345; GO:0075509; GO:0080025; GO:0097682 2645 XM_029335076.2 31 51 15 35 300 NA NA NA NA NA NA 2646 XM_029328443.2 155 0 0 180 5 NA NA NA NA NA NA 2647 XM_044322415.1 253 419 284 710 595 Q5BKF8 1.55e-56 Cyclin-L2 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) regulation of transcription by RNA polymerase II [GO:0006357] GO:0006357; GO:0016538; GO:0016607 2648 XM_029338248.2 568 363 452 241 324 O89110 9.51e-39 Caspase-8 (CASP-8) (EC 3.4.22.61) [Cleaved into: Caspase-8 subunit p18; Caspase-8 subunit p10] Mus musculus (Mouse) activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cardiac muscle tissue development [GO:0048738]; execution phase of apoptosis [GO:0097194]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; heart development [GO:0007507]; hepatocyte apoptotic process [GO:0097284]; macrophage differentiation [GO:0030225]; necroptotic process [GO:0070266]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of necroptotic process [GO:0060546]; neural tube formation [GO:0001841]; positive regulation of apoptotic process [GO:0043065]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of neuron death [GO:1901216]; positive regulation of proteolysis [GO:0045862]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; pyroptosis [GO:0070269]; regulation of apoptotic signaling pathway [GO:2001233]; regulation of cytokine production [GO:0001817]; regulation of innate immune response [GO:0045088]; regulation of thymocyte apoptotic process [GO:0070243]; response to ethanol [GO:0045471]; response to tumor necrosis factor [GO:0034612]; self proteolysis [GO:0097264]; TRAIL-activated apoptotic signaling pathway [GO:0036462] GO:0001525; GO:0001817; GO:0001841; GO:0004175; GO:0004197; GO:0005123; GO:0005164; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005829; GO:0005886; GO:0006508; GO:0006915; GO:0006919; GO:0007507; GO:0008233; GO:0008303; GO:0008625; GO:0016485; GO:0030225; GO:0030690; GO:0031264; GO:0031265; GO:0031625; GO:0032731; GO:0032991; GO:0034612; GO:0035877; GO:0036462; GO:0042802; GO:0043005; GO:0043065; GO:0043123; GO:0043124; GO:0044297; GO:0044877; GO:0045088; GO:0045121; GO:0045471; GO:0045651; GO:0045862; GO:0048738; GO:0051603; GO:0060546; GO:0070243; GO:0070266; GO:0070269; GO:0097110; GO:0097153; GO:0097190; GO:0097191; GO:0097194; GO:0097199; GO:0097200; GO:0097202; GO:0097264; GO:0097284; GO:0097342; GO:1901216; GO:2001233; GO:2001238 2649 XM_044317690.1 6 12 2 9 0 NA NA NA NA NA NA 2650 XM_044315250.1 0 30 0 0 0 NA NA NA NA NA NA 2651 XM_044327264.1 5 2 6 0 0 Q94K49 8.06e-44 Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1 (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) epigenetic regulation of gene expression [GO:0040029] GO:0003682; GO:0004518; GO:0005634; GO:0035098; GO:0035102; GO:0040029; GO:0046872 2652 XM_029355642.2 6 0 23 1 80 NA NA NA NA NA NA 2653 XM_044313757.1 0 1 0 7 0 NA NA NA NA NA NA 2654 XM_044322587.1 9 6 17 10 9 NA NA NA NA NA NA 2655 XM_044322412.1 395 222 165 398 164 A7S2N8 0 E3 UFM1-protein ligase 1 homolog (EC 2.3.2.-) (E3 UFM1-protein transferase 1 homolog) Nematostella vectensis (Starlet sea anemone) protein K69-linked ufmylation [GO:1990592]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]; response to endoplasmic reticulum stress [GO:0034976] GO:0005789; GO:0032434; GO:0034976; GO:0061666; GO:0071568; GO:1990592 2656 XM_029339657.2 76 158 87 99 49 Q9WYP5 3.48e-60 Myo-inositol 2-dehydrogenase (EC 1.1.1.18) Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) inositol metabolic process [GO:0006020]; NADPH regeneration [GO:0006740] GO:0000166; GO:0006020; GO:0006740; GO:0016491; GO:0050112 2657 XM_029357144.2 418 260 142 146 0 NA NA NA NA NA NA 2658 XM_044327706.1 52 75 178 45 474 NA NA NA NA NA NA 2659 XM_029328616.2 0 172 0 0 521 F1Q4S1 0 Probable phospholipid-transporting ATPase IIB (EC 7.6.2.1) (ATPase class II type 9B) Danio rerio (Zebrafish) (Brachydanio rerio) endocytosis [GO:0006897]; phospholipid translocation [GO:0045332]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] GO:0000287; GO:0005524; GO:0005768; GO:0005802; GO:0005886; GO:0006890; GO:0006897; GO:0016887; GO:0045332; GO:0140326 2660 XM_044321471.1 1396 914 1105 1189 2696 Q4R628 0 Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) centriole-centriole cohesion [GO:0010457]; cilium assembly [GO:0060271]; microtubule anchoring at centrosome [GO:0034454]; microtubule-based movement [GO:0007018] GO:0003777; GO:0005524; GO:0005737; GO:0005814; GO:0005874; GO:0005929; GO:0007018; GO:0008017; GO:0010457; GO:0034454; GO:0060271 2661 XM_029329167.2 1275 826 702 1225 1232 NA NA NA NA NA NA 2662 XM_029337944.2 286 468 191 400 288 NA NA NA NA NA NA 2663 XM_029326292.2 3 0 4 22 191 NA NA NA NA NA NA 2664 XM_044309269.1 195 0 0 13 3 NA NA NA NA NA NA 2665 XM_044318859.1 0 0 13 0 0 NA NA NA NA NA NA 2666 XM_029346821.2 2934 4085 1924 3487 2345 P62744 3.94e-82 AP-2 complex subunit sigma (Adaptor protein complex AP-2 subunit sigma) (Adaptor-related protein complex 2 subunit sigma) (Clathrin assembly protein 2 sigma small chain) (Clathrin coat assembly protein AP17) (Clathrin coat-associated protein AP17) (Plasma membrane adaptor AP-2 17 kDa protein) (Sigma-adaptin 3b) (Sigma2-adaptin) Rattus norvegicus (Rat) clathrin-dependent endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; synaptic vesicle endocytosis [GO:0048488]; vesicle-mediated transport [GO:0016192] GO:0005886; GO:0006886; GO:0016192; GO:0030122; GO:0035615; GO:0043231; GO:0045202; GO:0048488; GO:0072583; GO:0098794; GO:0098884; GO:0098894; GO:0098978 2667 XM_029339887.2 2230 1491 1428 2459 2888 Q8IZQ1 0 WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy) Homo sapiens (Human) aggrephagy [GO:0035973] GO:0000421; GO:0005545; GO:0005635; GO:0005654; GO:0005730; GO:0005737; GO:0005776; GO:0005829; GO:0005886; GO:0016020; GO:0016234; GO:0016605; GO:0030424; GO:0031965; GO:0035973; GO:0043204; GO:0046872 2668 XM_029339887.2 2230 1491 1428 2459 2888 Q8IZQ1 0 WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy) Homo sapiens (Human) aggrephagy [GO:0035973] GO:0000421; GO:0005545; GO:0005635; GO:0005654; GO:0005730; GO:0005737; GO:0005776; GO:0005829; GO:0005886; GO:0016020; GO:0016234; GO:0016605; GO:0030424; GO:0031965; GO:0035973; GO:0043204; GO:0046872 2669 XR_006397579.1 56 14 13 13 62 NA NA NA NA NA NA 2670 XM_044324332.1 758 462 269 532 422 O00303 2.67e-103 Eukaryotic translation initiation factor 3 subunit F (eIF3f) (Deubiquitinating enzyme eIF3f) (EC 3.4.19.12) (Eukaryotic translation initiation factor 3 subunit 5) (eIF-3-epsilon) (eIF3 p47) Homo sapiens (Human) formation of cytoplasmic translation initiation complex [GO:0001732]; IRES-dependent viral translational initiation [GO:0075522]; protein deubiquitination [GO:0016579]; translational initiation [GO:0006413] GO:0001732; GO:0003743; GO:0004843; GO:0005829; GO:0005852; GO:0006413; GO:0016020; GO:0016282; GO:0016579; GO:0031369; GO:0033290; GO:0042802; GO:0045202; GO:0071541; GO:0075522; GO:0140492 2671 XR_006393799.1 29 34 56 30 35 NA NA NA NA NA NA 2672 XM_044318912.1 270 158 178 307 482 C9D7C2 0 Voltage-dependent calcium channel type A subunit alpha-1 (Cacophony protein) Apis mellifera (Honeybee) regulation of ion transmembrane transport [GO:0034765] GO:0005245; GO:0005509; GO:0005891; GO:0034765 2673 XM_044309829.1 366 276 304 291 353 NA NA NA NA NA NA 2674 XM_029335435.2 7 3 0 7 11 NA NA NA NA NA NA 2675 XM_029325918.2 93 16 2 60 34 NA NA NA NA NA NA 2676 XM_044325452.1 5 24 30 0 0 P49887 2.42e-52 Sulfotransferase 1E1 (ST1E1) (EC 2.8.2.4) (Estrogen sulfotransferase) (ST1E3) (Sulfotransferase, estrogen-preferring) Cavia porcellus (Guinea pig) 3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; estrogen catabolic process [GO:0006711]; estrogen metabolic process [GO:0008210]; ethanol catabolic process [GO:0006068]; positive regulation of fat cell differentiation [GO:0045600]; sulfation [GO:0051923] GO:0004304; GO:0005496; GO:0005829; GO:0006068; GO:0006711; GO:0008210; GO:0031965; GO:0045600; GO:0047894; GO:0050294; GO:0050427; GO:0051923 2677 XM_044316226.1 102 14 17 74 188 NA NA NA NA NA NA 2678 XM_044314263.1 12 3 0 5 13 NA NA NA NA NA NA 2679 XM_029349938.2 0 1 5 8 0 NA NA NA NA NA NA 2680 XM_044321537.1 3 0 0 7 28 NA NA NA NA NA NA 2681 XM_044307378.1 2256 68 5046 3432 506 NA NA NA NA NA NA 2682 XR_006395826.1 2 21 20 2 6 NA NA NA NA NA NA 2683 XM_044327859.1 0 2 16 0 0 NA NA NA NA NA NA 2684 XM_029346662.2 2271 912 1207 2333 2857 Q01728 0 Sodium/calcium exchanger 1 (Na(+)/Ca(2+)-exchange protein 1) (Solute carrier family 8 member 1) Rattus norvegicus (Rat) calcium ion export [GO:1901660]; calcium ion homeostasis [GO:0055074]; calcium ion import [GO:0070509]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; calcium ion transport into cytosol [GO:0060402]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cell communication by electrical coupling involved in cardiac conduction [GO:0086064]; cellular calcium ion homeostasis [GO:0006874]; cellular response to caffeine [GO:0071313]; cellular response to cAMP [GO:0071320]; cellular response to hypoxia [GO:0071456]; cellular response to reactive oxygen species [GO:0034614]; cellular sodium ion homeostasis [GO:0006883]; embryonic heart tube development [GO:0035050]; embryonic placenta development [GO:0001892]; heart morphogenesis [GO:0003007]; metal ion transport [GO:0030001]; muscle cell development [GO:0055001]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of the force of heart contraction [GO:0098735]; post-embryonic development [GO:0009791]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of gene expression [GO:0010468]; regulation of heart rate [GO:0002027]; regulation of sodium ion transport [GO:0002028]; regulation of the force of heart contraction [GO:0002026]; relaxation of smooth muscle [GO:0044557]; response to ATP [GO:0033198]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to immobilization stress [GO:0035902]; response to muscle stretch [GO:0035994]; response to nutrient [GO:0007584]; response to xenobiotic stimulus [GO:0009410]; sodium ion export across plasma membrane [GO:0036376]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814]; telencephalon development [GO:0021537]; vascular associated smooth muscle contraction [GO:0014829] GO:0001666; GO:0001892; GO:0002026; GO:0002027; GO:0002028; GO:0003007; GO:0005432; GO:0005509; GO:0005516; GO:0005654; GO:0005739; GO:0005874; GO:0005886; GO:0006814; GO:0006816; GO:0006874; GO:0006883; GO:0007204; GO:0007584; GO:0008092; GO:0009410; GO:0009749; GO:0009791; GO:0010468; GO:0010763; GO:0010881; GO:0014069; GO:0014704; GO:0014829; GO:0016020; GO:0016323; GO:0021537; GO:0030001; GO:0030018; GO:0030315; GO:0030424; GO:0030425; GO:0030501; GO:0030506; GO:0033198; GO:0034614; GO:0035050; GO:0035725; GO:0035902; GO:0035994; GO:0036376; GO:0042383; GO:0042542; GO:0042995; GO:0043025; GO:0043197; GO:0043198; GO:0043679; GO:0044325; GO:0044557; GO:0045202; GO:0045211; GO:0051481; GO:0051924; GO:0055001; GO:0055013; GO:0055074; GO:0060048; GO:0060402; GO:0070509; GO:0070588; GO:0071313; GO:0071320; GO:0071456; GO:0071901; GO:0071944; GO:0086064; GO:0098703; GO:0098719; GO:0098735; GO:0098794; GO:0099580; GO:1901660; GO:1905060 2685 XM_029335381.2 2501 2554 1136 2167 1165 Q99571 2.49e-129 P2X purinoceptor 4 (P2X4) (ATP receptor) (Purinergic receptor) Homo sapiens (Human) apoptotic signaling pathway [GO:0097190]; behavioral response to pain [GO:0048266]; calcium ion transmembrane transport [GO:0070588]; calcium-mediated signaling [GO:0019722]; cellular response to ATP [GO:0071318]; cellular response to zinc ion [GO:0071294]; endothelial cell activation [GO:0042118]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; neuronal action potential [GO:0019228]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of microglial cell migration [GO:1904141]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein kinase B signaling [GO:0051897]; purinergic nucleotide receptor signaling pathway [GO:0035590]; regulation of blood pressure [GO:0008217]; regulation of cardiac muscle contraction [GO:0055117]; regulation of chemotaxis [GO:0050920]; regulation of sodium ion transport [GO:0002028]; relaxation of cardiac muscle [GO:0055119]; response to ATP [GO:0033198]; response to axon injury [GO:0048678]; response to fluid shear stress [GO:0034405]; response to ischemia [GO:0002931]; sensory perception of pain [GO:0019233]; sensory perception of touch [GO:0050975]; signal transduction [GO:0007165]; tissue homeostasis [GO:0001894] GO:0001614; GO:0001894; GO:0002028; GO:0002931; GO:0004931; GO:0005102; GO:0005507; GO:0005524; GO:0005637; GO:0005765; GO:0005886; GO:0007165; GO:0008217; GO:0008270; GO:0010524; GO:0010614; GO:0014069; GO:0016020; GO:0019228; GO:0019233; GO:0019722; GO:0030054; GO:0032308; GO:0033198; GO:0034220; GO:0034405; GO:0035590; GO:0042118; GO:0042802; GO:0043025; GO:0043195; GO:0043197; GO:0043536; GO:0044297; GO:0045296; GO:0045429; GO:0048266; GO:0048471; GO:0048678; GO:0050850; GO:0050920; GO:0050975; GO:0051897; GO:0051899; GO:0051928; GO:0055117; GO:0055119; GO:0070062; GO:0070588; GO:0071294; GO:0071318; GO:0097190; GO:0099604; GO:1904141; GO:2001028 2686 XM_029346933.2 49 49 47 38 37 NA NA NA NA NA NA 2687 XM_044326379.1 859 809 796 1252 677 Q24270 0 Voltage-dependent calcium channel type D subunit alpha-1 (DmCa1D) Drosophila melanogaster (Fruit fly) calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; calcium-mediated signaling [GO:0019722]; epithelial fluid transport [GO:0042045]; locomotion [GO:0040011]; muscle contraction [GO:0006936]; neuron remodeling [GO:0016322]; regulation of ion transmembrane transport [GO:0034765] GO:0005245; GO:0005891; GO:0006816; GO:0006936; GO:0008331; GO:0016322; GO:0016323; GO:0016324; GO:0019722; GO:0034765; GO:0040011; GO:0042045; GO:0046872; GO:0070588; GO:0098703 2688 XM_029354870.2 1521 1394 711 1188 827 NA NA NA NA NA NA 2689 XM_029334832.2 404 190 367 308 161 NA NA NA NA NA NA 2690 XM_044321816.1 10 12 5 13 14 NA NA NA NA NA NA 2691 XM_044323528.1 0 0 2 0 76 NA NA NA NA NA NA 2692 XM_029329801.2 117 31 25 35 42 NA NA NA NA NA NA 2693 XM_044324665.1 0 0 4 6 0 NA NA NA NA NA NA 2694 XM_044307137.1 333 533 157 424 344 NA NA NA NA NA NA 2695 XM_044312654.1 0 0 1 0 10 NA NA NA NA NA NA 2696 XM_044307690.1 2436 1736 111 2394 188 NA NA NA NA NA NA 2697 XM_044310451.1 60 8 22 14 82 NA NA NA NA NA NA 2698 XM_029333876.2 221 198 200 213 184 NA NA NA NA NA NA 2699 XM_044307606.1 883 783 715 1111 1069 C9D7C2 0 Voltage-dependent calcium channel type A subunit alpha-1 (Cacophony protein) Apis mellifera (Honeybee) regulation of ion transmembrane transport [GO:0034765] GO:0005245; GO:0005509; GO:0005891; GO:0034765 2700 XM_044307606.1 883 783 715 1111 1069 C9D7C2 5.33e-165 Voltage-dependent calcium channel type A subunit alpha-1 (Cacophony protein) Apis mellifera (Honeybee) regulation of ion transmembrane transport [GO:0034765] GO:0005245; GO:0005509; GO:0005891; GO:0034765 2701 XM_044307606.1 883 783 715 1111 1069 C9D7C2 3.72e-33 Voltage-dependent calcium channel type A subunit alpha-1 (Cacophony protein) Apis mellifera (Honeybee) regulation of ion transmembrane transport [GO:0034765] GO:0005245; GO:0005509; GO:0005891; GO:0034765 2702 XM_044318803.1 37 0 29 48 123 P07550 1.28e-24 Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor) Homo sapiens (Human) activation of adenylate cyclase activity [GO:0007190]; activation of transmembrane receptor protein tyrosine kinase activity [GO:0007171]; adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; adrenergic receptor signaling pathway [GO:0071875]; bone resorption [GO:0045453]; brown fat cell differentiation [GO:0050873]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amyloid-beta [GO:1904646]; desensitization of G protein-coupled receptor signaling pathway by arrestin [GO:0002032]; diet induced thermogenesis [GO:0002024]; endosome to lysosome transport [GO:0008333]; heat generation [GO:0031649]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of smooth muscle contraction [GO:0045986]; norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0002025]; positive regulation of AMPA receptor activity [GO:2000969]; positive regulation of autophagosome maturation [GO:1901098]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cAMP-dependent protein kinase activity [GO:2000481]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of lipophagy [GO:1904504]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mini excitatory postsynaptic potential [GO:0061885]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor-mediated endocytosis [GO:0006898]; regulation of sodium ion transport [GO:0002028]; response to cold [GO:0009409]; response to psychosocial stress [GO:1990911]; smooth muscle contraction [GO:0006939]; transcription by RNA polymerase II [GO:0006366] GO:0001540; GO:0002024; GO:0002025; GO:0002028; GO:0002032; GO:0004930; GO:0004941; GO:0005634; GO:0005764; GO:0005768; GO:0005769; GO:0005794; GO:0005886; GO:0006366; GO:0006898; GO:0006939; GO:0007166; GO:0007171; GO:0007188; GO:0007190; GO:0008179; GO:0008333; GO:0009409; GO:0010008; GO:0010739; GO:0015459; GO:0016020; GO:0016324; GO:0030501; GO:0030669; GO:0031649; GO:0040015; GO:0042802; GO:0042803; GO:0043235; GO:0043410; GO:0044877; GO:0045453; GO:0045944; GO:0045986; GO:0050873; GO:0051380; GO:0061885; GO:0071875; GO:0071880; GO:0071902; GO:0098992; GO:0120162; GO:1901098; GO:1904504; GO:1904646; GO:1990911; GO:2000481; GO:2000969 2703 XR_006392371.1 13 0 11 1 43 NA NA NA NA NA NA 2704 XM_044310860.1 0 0 0 22 2 Q5R9I3 2.64e-24 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cellular response to glucose starvation [GO:0042149]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; protein phosphorylation [GO:0006468] GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005930; GO:0006468; GO:0016236; GO:0035032; GO:0042149; GO:0045324; GO:0106310 2705 XM_044326876.1 198 121 61 218 167 A1KZ92 7.19e-25 Probable oxidoreductase PXDNL (EC 1.-.-.-) (Cardiac peroxidase) (Inactive peroxidasin-like protein) (Polysomal ribonuclease 1) (PRM1) (Vascular peroxidase 2) Homo sapiens (Human) hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979] GO:0004519; GO:0004601; GO:0005615; GO:0005783; GO:0005886; GO:0006979; GO:0020037; GO:0042744; GO:0046872; GO:0140825 2706 XM_029339682.2 217 222 261 337 366 Q924H0 1.06e-27 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide NPFF receptor) Mus musculus (Mouse) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 2707 XM_029356276.2 20 48 77 1 92 Q6P832 0 Glycine amidinotransferase, mitochondrial (EC 2.1.4.1) (L-arginine:glycine amidinotransferase) (Transamidinase) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) creatine biosynthetic process [GO:0006601] GO:0005743; GO:0006601; GO:0015068 2708 XM_044314010.1 37 0 0 21 21 A6NE52 1e-69 WD repeat-containing protein 97 Homo sapiens (Human) NA NA 2709 XM_044328747.1 6746 3204 1313 14800 15411 B3EWY6 3.21e-24 Skeletal aspartic acid-rich protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 2710 XM_044328182.1 0 7 9 2 5 P35061 1.57e-61 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 2711 XM_044319666.1 43 178 0 216 42 Q69Z28 4.25e-159 A disintegrin and metalloproteinase with thrombospondin motifs 16 (ADAM-TS 16) (ADAM-TS16) (ADAMTS-16) (EC 3.4.24.-) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; extracellular matrix organization [GO:0030198]; male gamete generation [GO:0048232]; proteolysis [GO:0006508]; regulation of cilium assembly [GO:1902017]; regulation of systemic arterial blood pressure [GO:0003073] GO:0001658; GO:0003073; GO:0004222; GO:0005576; GO:0006508; GO:0030198; GO:0031012; GO:0046872; GO:0048232; GO:1902017 2712 XM_044314443.1 626 402 185 674 457 Q8R332 6.06e-61 Nucleoporin p58/p45 (58 kDa nucleoporin) (Nucleoporin-like protein 1) Mus musculus (Mouse) mRNA transport [GO:0051028]; nucleocytoplasmic transport [GO:0006913]; protein transport [GO:0015031]; regulation of protein import into nucleus [GO:0042306] GO:0005635; GO:0005643; GO:0006913; GO:0008139; GO:0015031; GO:0017056; GO:0031965; GO:0032991; GO:0042306; GO:0042802; GO:0044877; GO:0051028 2713 XM_029337984.2 62 47 273 1392 590 Q90632 2.01e-37 Monocarboxylate transporter 3 (MCT 3) (Retinal epithelial membrane protein) (Solute carrier family 16 member 8) Gallus gallus (Chicken) monocarboxylic acid transport [GO:0015718] GO:0005886; GO:0008028; GO:0015293; GO:0015718; GO:0016020; GO:0016323 2714 XM_044323897.1 73 77 58 161 151 NA NA NA NA NA NA 2715 XR_006391541.1 112 0 16 0 132 NA NA NA NA NA NA 2716 XM_044312342.1 0 48 2 0 0 NA NA NA NA NA NA 2717 XM_029349348.2 50 24 13 7 35 NA NA NA NA NA NA 2718 XM_044316461.1 0 12 0 4 18 NA NA NA NA NA NA 2719 XR_006395400.1 0 0 13 0 20 NA NA NA NA NA NA 2720 XM_044314841.1 20 1 23 0 20 NA NA NA NA NA NA 2721 XM_044308342.1 18 0 9 1 150 NA NA NA NA NA NA 2722 XM_029355987.2 0 0 32 0 0 NA NA NA NA NA NA 2723 XM_044311657.1 0 0 0 0 45 B8VIU6 7.82e-69 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 2724 XM_029350629.2 1102 656 466 1755 1840 NA NA NA NA NA NA 2725 XM_044312789.1 0 0 0 0 15 NA NA NA NA NA NA 2726 XM_029335023.2 509 313 192 344 653 Q96QG7 0 Myotubularin-related protein 9 (Inactive phosphatidylinositol 3-phosphatase 9) Homo sapiens (Human) endocytosis [GO:0006897]; negative regulation of autophagy [GO:0010507]; phosphatidylinositol dephosphorylation [GO:0046856]; positive regulation of phosphatase activity [GO:0010922]; protein stabilization [GO:0050821]; regulation of phosphatidylinositol dephosphorylation [GO:0060304] GO:0004438; GO:0005737; GO:0005783; GO:0005829; GO:0006897; GO:0010507; GO:0010922; GO:0019903; GO:0030234; GO:0032587; GO:0032991; GO:0046856; GO:0048471; GO:0050821; GO:0060304 2727 XM_044320881.1 117 128 47 115 139 NA NA NA NA NA NA 2728 XM_029347288.2 1883 1091 1182 1424 897 O88327 1.09e-114 Alpha-catulin (Alpha-catenin-related protein) (ACRP) (Catenin alpha-like protein 1) Mus musculus (Mouse) cell adhesion [GO:0007155]; Rho protein signal transduction [GO:0007266] GO:0005829; GO:0005856; GO:0005886; GO:0005911; GO:0007155; GO:0007266; GO:0045296; GO:0051015 2729 XM_044310139.1 164 322 110 75 357 NA NA NA NA NA NA 2730 XM_044313324.1 17 4 0 20 21 Q9EQD2 1.87e-44 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 2731 XM_044308480.1 0 0 0 0 9 NA NA NA NA NA NA 2732 XM_044310911.1 346 3 0 0 11 Q7RTR2 5.33e-41 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 2733 XM_044310911.1 346 3 0 0 11 Q7RTR2 1.44e-32 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 2734 XM_044310911.1 346 3 0 0 11 Q7RTR2 5.32e-27 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 2735 XM_044310911.1 346 3 0 0 11 Q7RTR2 5.6e-27 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 2736 XM_044310911.1 346 3 0 0 11 Q7RTR2 2.52e-21 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 2737 XM_029353309.2 204 126 109 152 161 NA NA NA NA NA NA 2738 XM_044313497.1 46 0 1 8 0 P07911 1.86e-50 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Homo sapiens (Human) antibacterial innate immune response [GO:0140367]; apoptotic signaling pathway [GO:0097190]; autophagy [GO:0006914]; cellular calcium ion homeostasis [GO:0006874]; cellular chloride ion homeostasis [GO:0030644]; cellular defense response [GO:0006968]; cellular phosphate ion homeostasis [GO:0030643]; cellular response to unfolded protein [GO:0034620]; cellular sodium ion homeostasis [GO:0006883]; chaperone-mediated protein folding [GO:0061077]; citric acid secretion [GO:0046720]; collecting duct development [GO:0072044]; connective tissue replacement [GO:0097709]; creatinine homeostasis [GO:0097273]; defense response to Gram-negative bacterium [GO:0050829]; endoplasmic reticulum organization [GO:0007029]; glomerular filtration [GO:0003094]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; juxtaglomerular apparatus development [GO:0072051]; leukocyte cell-cell adhesion [GO:0007159]; lipid metabolic process [GO:0006629]; metanephric ascending thin limb development [GO:0072218]; metanephric distal convoluted tubule development [GO:0072221]; metanephric thick ascending limb development [GO:0072233]; micturition [GO:0060073]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell population proliferation [GO:0008285]; neutrophil migration [GO:1990266]; organ or tissue specific immune response [GO:0002251]; peptidyl-threonine phosphorylation [GO:0018107]; potassium ion homeostasis [GO:0055075]; protein localization to vacuole [GO:0072665]; protein transport into plasma membrane raft [GO:0044861]; regulation of blood pressure [GO:0008217]; regulation of protein transport [GO:0051223]; regulation of urine volume [GO:0035809]; renal sodium ion absorption [GO:0070294]; renal urate salt excretion [GO:0097744]; renal water homeostasis [GO:0003091]; response to lipopolysaccharide [GO:0032496]; response to water deprivation [GO:0009414]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; ubiquitin-dependent ERAD pathway [GO:0030433]; urate transport [GO:0015747]; urea transmembrane transport [GO:0071918] GO:0000922; GO:0002251; GO:0003091; GO:0003094; GO:0005201; GO:0005509; GO:0005615; GO:0005783; GO:0005796; GO:0005929; GO:0006629; GO:0006874; GO:0006883; GO:0006914; GO:0006954; GO:0006968; GO:0007029; GO:0007157; GO:0007159; GO:0008217; GO:0008285; GO:0008380; GO:0009410; GO:0009414; GO:0009986; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0018107; GO:0019864; GO:0019898; GO:0030433; GO:0030643; GO:0030644; GO:0032496; GO:0033209; GO:0033555; GO:0034620; GO:0035809; GO:0044861; GO:0046720; GO:0050829; GO:0051223; GO:0055075; GO:0060073; GO:0060170; GO:0061077; GO:0070062; GO:0070294; GO:0071918; GO:0072044; GO:0072051; GO:0072218; GO:0072221; GO:0072233; GO:0072665; GO:0097190; GO:0097273; GO:0097709; GO:0097744; GO:0140367; GO:1990266 2739 XR_003824226.2 24 42 12 81 31 NA NA NA NA NA NA 2740 XM_029331404.2 769 321 326 520 539 B3TP03 2.36e-84 Cationic amino acid transporter 2 (CAT-2) (CAT2) (cCAT-2) (Low affinity cationic amino acid transporter 2) (Solute carrier family 7 member 2) Gallus gallus (Chicken) amino acid transport [GO:0006865]; L-arginine import across plasma membrane [GO:0097638]; L-lysine import across plasma membrane [GO:0097639]; L-ornithine transmembrane transport [GO:1903352] GO:0000064; GO:0005737; GO:0005794; GO:0005886; GO:0006865; GO:0015171; GO:0015189; GO:0031410; GO:0061459; GO:0097638; GO:0097639; GO:1903352 2741 XM_029327417.2 3736 2854 2083 3112 1737 Q8BUL6 5.59e-32 Pleckstrin homology domain-containing family A member 1 (PH domain-containing family A member 1) (Tandem PH domain-containing protein 1) (TAPP-1) Mus musculus (Mouse) androgen metabolic process [GO:0008209]; B cell receptor signaling pathway [GO:0050853]; cellular response to hydrogen peroxide [GO:0070301]; establishment of protein localization [GO:0045184]; estrogen metabolic process [GO:0008210]; face morphogenesis [GO:0060325]; female gonad development [GO:0008585]; Leydig cell differentiation [GO:0033327]; luteinization [GO:0001553]; multicellular organism growth [GO:0035264]; negative regulation of protein kinase B signaling [GO:0051898]; phosphatidylinositol 3-kinase signaling [GO:0014065]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; post-embryonic development [GO:0009791]; roof of mouth development [GO:0060021]; ruffle organization [GO:0031529]; skeletal system morphogenesis [GO:0048705]; spermatogenesis [GO:0007283] GO:0001553; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0007283; GO:0008209; GO:0008210; GO:0008289; GO:0008585; GO:0009791; GO:0014065; GO:0016020; GO:0030165; GO:0031529; GO:0032587; GO:0033327; GO:0035264; GO:0043325; GO:0045184; GO:0048008; GO:0048705; GO:0050853; GO:0051898; GO:0060021; GO:0060325; GO:0070301 2742 XR_006394771.1 51 7 28 24 84 NA NA NA NA NA NA 2743 XM_044312057.1 18 12 38 5 11 NA NA NA NA NA NA 2744 XM_029350656.2 0 0 0 0 6 Q96PN8 4.11e-78 Testis-specific serine/threonine-protein kinase 3 (TSK-3) (TSSK-3) (Testis-specific kinase 3) (EC 2.7.11.1) (Serine/threonine-protein kinase 22C) Homo sapiens (Human) cell differentiation [GO:0030154]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]; spermatogenesis [GO:0007283] GO:0000287; GO:0004674; GO:0005524; GO:0006468; GO:0007283; GO:0030154; GO:0035556; GO:0106310 2745 XM_044321054.1 205 65 0 165 35 P23780 0 Beta-galactosidase (EC 3.2.1.23) (Acid beta-galactosidase) (Lactase) Mus musculus (Mouse) cellular carbohydrate metabolic process [GO:0044262]; galactose catabolic process [GO:0019388]; response to cortisone [GO:0051413]; response to Thyroglobulin triiodothyronine [GO:1904016] GO:0004565; GO:0005615; GO:0005737; GO:0005764; GO:0005773; GO:0005794; GO:0016787; GO:0016936; GO:0019388; GO:0042803; GO:0043231; GO:0044262; GO:0051413; GO:1904016 2746 XR_006395343.1 16 0 11 3 4 NA NA NA NA NA NA 2747 XM_044322893.1 18 65 22 2 58 Q8K4G1 1.77e-72 Latent-transforming growth factor beta-binding protein 4 (LTBP-4) Mus musculus (Mouse) elastic fiber assembly [GO:0048251]; hormone secretion [GO:0046879]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001527; GO:0005509; GO:0005576; GO:0007179; GO:0031012; GO:0046879; GO:0048251; GO:0050431; GO:0062023 2748 XM_044322893.1 18 65 22 2 58 Q8K4G1 2.9e-63 Latent-transforming growth factor beta-binding protein 4 (LTBP-4) Mus musculus (Mouse) elastic fiber assembly [GO:0048251]; hormone secretion [GO:0046879]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001527; GO:0005509; GO:0005576; GO:0007179; GO:0031012; GO:0046879; GO:0048251; GO:0050431; GO:0062023 2749 XM_044322893.1 18 65 22 2 58 Q8K4G1 3.86e-60 Latent-transforming growth factor beta-binding protein 4 (LTBP-4) Mus musculus (Mouse) elastic fiber assembly [GO:0048251]; hormone secretion [GO:0046879]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001527; GO:0005509; GO:0005576; GO:0007179; GO:0031012; GO:0046879; GO:0048251; GO:0050431; GO:0062023 2750 XM_044322893.1 18 65 22 2 58 Q8K4G1 5.9e-50 Latent-transforming growth factor beta-binding protein 4 (LTBP-4) Mus musculus (Mouse) elastic fiber assembly [GO:0048251]; hormone secretion [GO:0046879]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001527; GO:0005509; GO:0005576; GO:0007179; GO:0031012; GO:0046879; GO:0048251; GO:0050431; GO:0062023 2751 XM_044322893.1 18 65 22 2 58 Q8K4G1 1.02e-49 Latent-transforming growth factor beta-binding protein 4 (LTBP-4) Mus musculus (Mouse) elastic fiber assembly [GO:0048251]; hormone secretion [GO:0046879]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001527; GO:0005509; GO:0005576; GO:0007179; GO:0031012; GO:0046879; GO:0048251; GO:0050431; GO:0062023 2752 XM_044322893.1 18 65 22 2 58 Q8K4G1 8.23e-25 Latent-transforming growth factor beta-binding protein 4 (LTBP-4) Mus musculus (Mouse) elastic fiber assembly [GO:0048251]; hormone secretion [GO:0046879]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001527; GO:0005509; GO:0005576; GO:0007179; GO:0031012; GO:0046879; GO:0048251; GO:0050431; GO:0062023 2753 XM_029346916.2 595 5943 273 1027 5476 NA NA NA NA NA NA 2754 XM_029356259.2 538 381 112 345 221 NA NA NA NA NA NA 2755 XM_029333458.2 1419 865 687 1069 1078 P49756 1.95e-53 RNA-binding protein 25 (Arg/Glu/Asp-rich protein of 120 kDa) (RED120) (Protein S164) (RNA-binding motif protein 25) (RNA-binding region-containing protein 7) Homo sapiens (Human) mRNA processing [GO:0006397]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of apoptotic process [GO:0042981]; RNA splicing [GO:0008380] GO:0000381; GO:0003723; GO:0003729; GO:0005737; GO:0006397; GO:0008380; GO:0016607; GO:0042981 2756 XM_029333458.2 1419 865 687 1069 1078 P49756 4.58e-33 RNA-binding protein 25 (Arg/Glu/Asp-rich protein of 120 kDa) (RED120) (Protein S164) (RNA-binding motif protein 25) (RNA-binding region-containing protein 7) Homo sapiens (Human) mRNA processing [GO:0006397]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of apoptotic process [GO:0042981]; RNA splicing [GO:0008380] GO:0000381; GO:0003723; GO:0003729; GO:0005737; GO:0006397; GO:0008380; GO:0016607; GO:0042981 2757 XR_006391330.1 52 8 13 24 17 NA NA NA NA NA NA 2758 XM_044308503.1 25 1 76 3 56 NA NA NA NA NA NA 2759 XM_029341928.2 456 111 0 0 0 P97677 4.76e-84 Delta-like protein 1 (Drosophila Delta homolog 1) (Delta1) Rattus norvegicus (Rat) astrocyte development [GO:0014002]; auditory receptor cell fate commitment [GO:0009912]; cell fate determination [GO:0001709]; cell-cell signaling [GO:0007267]; cerebellar molecular layer formation [GO:0021688]; cerebellar Purkinje cell layer structural organization [GO:0021693]; clathrin-dependent endocytosis [GO:0072583]; compartment pattern specification [GO:0007386]; determination of left/right symmetry [GO:0007368]; endothelial tip cell fate specification [GO:0097102]; energy homeostasis [GO:0097009]; heart looping [GO:0001947]; inhibition of neuroepithelial cell differentiation [GO:0002085]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear development [GO:0048839]; lateral inhibition [GO:0046331]; left/right axis specification [GO:0070986]; loop of Henle development [GO:0072070]; marginal zone B cell differentiation [GO:0002315]; myeloid cell differentiation [GO:0030099]; negative regulation of cardiac muscle cell differentiation [GO:2000726]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal cell differentiation [GO:0045605]; negative regulation of epithelial cell differentiation [GO:0030857]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of inner ear auditory receptor cell differentiation [GO:0045608]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of Notch signaling pathway [GO:0045746]; nephron development [GO:0072006]; nervous system development [GO:0007399]; neuroepithelial cell differentiation [GO:0060563]; neuron differentiation [GO:0030182]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; Notch signaling pathway involved in arterial endothelial cell fate commitment [GO:0060853]; organ growth [GO:0035265]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endocytosis [GO:0045807]; positive regulation of gene expression [GO:0010628]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of skeletal muscle tissue growth [GO:0048633]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proximal tubule development [GO:0072014]; proximal/distal pattern formation [GO:0009954]; regulation of blood pressure [GO:0008217]; regulation of cell adhesion [GO:0030155]; regulation of cell division [GO:0051302]; regulation of growth [GO:0040008]; regulation of neurogenesis [GO:0050767]; regulation of skeletal muscle tissue growth [GO:0048631]; regulation of somitogenesis [GO:0014807]; regulation of vascular endothelial growth factor signaling pathway [GO:1900746]; retina development in camera-type eye [GO:0060041]; retina morphogenesis in camera-type eye [GO:0060042]; skeletal muscle tissue growth [GO:0048630]; skin epidermis development [GO:0098773]; somite specification [GO:0001757]; somitogenesis [GO:0001756]; spinal cord development [GO:0021510]; type B pancreatic cell development [GO:0003323] GO:0001709; GO:0001756; GO:0001757; GO:0001947; GO:0002085; GO:0002315; GO:0003323; GO:0005112; GO:0005509; GO:0005886; GO:0005912; GO:0007219; GO:0007267; GO:0007368; GO:0007386; GO:0007399; GO:0008217; GO:0008284; GO:0008285; GO:0009912; GO:0009954; GO:0010628; GO:0014002; GO:0014807; GO:0016324; GO:0021510; GO:0021688; GO:0021693; GO:0030099; GO:0030155; GO:0030182; GO:0030857; GO:0030957; GO:0031410; GO:0032693; GO:0034351; GO:0035265; GO:0040008; GO:0042491; GO:0045121; GO:0045596; GO:0045605; GO:0045608; GO:0045638; GO:0045662; GO:0045665; GO:0045746; GO:0045747; GO:0045807; GO:0045944; GO:0046331; GO:0048018; GO:0048630; GO:0048631; GO:0048633; GO:0048665; GO:0048839; GO:0050767; GO:0051302; GO:0060041; GO:0060042; GO:0060563; GO:0060853; GO:0070986; GO:0072006; GO:0072014; GO:0072070; GO:0072583; GO:0097009; GO:0097102; GO:0097110; GO:0097150; GO:0098773; GO:1900746; GO:1903672; GO:2000726 2760 XM_029333509.2 6999 5878 3700 5764 5488 Q9XTL9 0 Glycogen phosphorylase (EC 2.4.1.1) Drosophila melanogaster (Fruit fly) defense response to Gram-negative bacterium [GO:0050829]; determination of adult lifespan [GO:0008340]; glycogen catabolic process [GO:0005980]; insulin receptor signaling pathway [GO:0008286]; negative regulation of innate immune response [GO:0045824]; positive regulation of glycogen catabolic process [GO:0045819] GO:0005737; GO:0005980; GO:0008184; GO:0008286; GO:0008340; GO:0030170; GO:0032991; GO:0042803; GO:0045819; GO:0045824; GO:0050829; GO:0102250; GO:0102499 2761 XR_006392839.1 673 66 753 598 740 NA NA NA NA NA NA 2762 XM_044322296.1 0 2 7 0 0 NA NA NA NA NA NA 2763 XM_029343976.2 0 0 85 59 57 B9EJ86 0 Oxysterol-binding protein-related protein 8 (ORP-8) (OSBP-related protein 8) Mus musculus (Mouse) activation of protein kinase B activity [GO:0032148]; fat cell differentiation [GO:0045444]; negative regulation of cell migration [GO:0030336]; negative regulation of sequestering of triglyceride [GO:0010891]; phospholipid transport [GO:0015914]; positive regulation of glucose import [GO:0046326]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of protein kinase B signaling [GO:0051897]; protein localization to nuclear pore [GO:0090204] GO:0001786; GO:0005783; GO:0005789; GO:0005829; GO:0010891; GO:0015248; GO:0015485; GO:0015914; GO:0016020; GO:0030336; GO:0031965; GO:0032148; GO:0032541; GO:0032934; GO:0043231; GO:0045444; GO:0046326; GO:0046628; GO:0051897; GO:0070273; GO:0090204; GO:0140343 2764 XM_029345413.2 11 0 0 0 0 Q9V3R8 3.94e-27 UbiA prenyltransferase domain-containing protein 1 homolog (EC 2.5.1.-) (Protein heixuedian) Drosophila melanogaster (Fruit fly) larval lymph gland hemopoiesis [GO:0035167]; menaquinone biosynthetic process [GO:0009234]; mitochondrion morphogenesis [GO:0070584]; negative regulation of hemocyte differentiation [GO:0045611]; negative regulation of hemocyte proliferation [GO:0035207]; negative regulation of lamellocyte differentiation [GO:0035204]; ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate [GO:0032194]; vitamin K biosynthetic process [GO:0042371] GO:0000139; GO:0004659; GO:0005739; GO:0005783; GO:0009234; GO:0016020; GO:0031966; GO:0032194; GO:0035167; GO:0035204; GO:0035207; GO:0042371; GO:0045611; GO:0070584 2765 XM_029328306.2 57 17 6 0 120 NA NA NA NA NA NA 2766 XM_044322499.1 534 1001 260 250 1522 NA NA NA NA NA NA 2767 XM_029335785.2 361 243 166 261 181 Q7ZYG5 1.53e-87 Protein MAK16 homolog B (MAK16-like protein B) Xenopus laevis (African clawed frog) NA GO:0005730 2768 XM_029350265.2 127 166 28 113 66 Q96JL9 7.5e-39 Zinc finger protein 333 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 2769 XM_029350265.2 127 166 28 113 66 Q96JL9 4.6e-30 Zinc finger protein 333 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 2770 XM_029350265.2 127 166 28 113 66 Q96JL9 1.56e-29 Zinc finger protein 333 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 2771 XM_029350265.2 127 166 28 113 66 Q96JL9 3.87e-29 Zinc finger protein 333 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 2772 XM_029350265.2 127 166 28 113 66 Q96JL9 5.9e-28 Zinc finger protein 333 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 2773 XM_044312945.1 26 0 15 0 110 NA NA NA NA NA NA 2774 XM_044307654.1 13 4 0 8 2 NA NA NA NA NA NA 2775 XM_029352587.2 7 0 0 0 0 NA NA NA NA NA NA 2776 XM_029333693.2 3002 2498 1547 1903 1863 Q8BZ21 1.79e-45 Histone acetyltransferase KAT6A (EC 2.3.1.48) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (MYST-3) (Monocytic leukemia zinc finger homolog) (Monocytic leukemia zinc finger protein) Mus musculus (Mouse) aorta morphogenesis [GO:0035909]; cellular senescence [GO:0090398]; embryonic hemopoiesis [GO:0035162]; face morphogenesis [GO:0060325]; heart morphogenesis [GO:0003007]; histone H3 acetylation [GO:0043966]; myeloid cell differentiation [GO:0030099]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA-templated transcription [GO:0045892]; nucleosome assembly [GO:0006334]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein acetylation [GO:0006473]; regulation of developmental process [GO:0050793]; regulation of DNA-templated transcription [GO:0006355]; regulation of hemopoiesis [GO:1903706]; somatic stem cell population maintenance [GO:0035019] GO:0000786; GO:0003007; GO:0003677; GO:0003682; GO:0003712; GO:0003713; GO:0004402; GO:0005634; GO:0005730; GO:0005829; GO:0006334; GO:0006355; GO:0006473; GO:0008270; GO:0010628; GO:0016605; GO:0016607; GO:0030099; GO:0035019; GO:0035162; GO:0035909; GO:0036408; GO:0042393; GO:0043433; GO:0043966; GO:0043992; GO:0043995; GO:0043996; GO:0043997; GO:0045892; GO:0045893; GO:0045944; GO:0046972; GO:0050793; GO:0060325; GO:0070776; GO:0090398; GO:0140297; GO:1903706 2777 XM_044314307.1 0 0 2 15 3 NA NA NA NA NA NA 2778 XR_006394797.1 64 25 25 31 52 NA NA NA NA NA NA 2779 XM_029351282.2 105 96 22 67 42 Q93XX5 1.17e-32 PI-PLC X domain-containing protein At5g67130 Arabidopsis thaliana (Mouse-ear cress) lipid metabolic process [GO:0006629] GO:0005886; GO:0006629; GO:0008081; GO:0009536 2780 XR_006394055.1 0 0 0 0 62 NA NA NA NA NA NA 2781 XM_044328367.1 39 22 11 50 34 NA NA NA NA NA NA 2782 XM_029332907.2 0 0 24 51 0 Q8AY73 0 Exportin-2 (Exp2) (Cellular apoptosis susceptibility protein) (Chromosome segregation 1-like protein) (Importin-alpha re-exporter) Oreochromis niloticus (Nile tilapia) (Tilapia nilotica) intracellular protein transport [GO:0006886] GO:0005634; GO:0005737; GO:0006886; GO:0031267 2783 XR_006396405.1 17 12 0 22 9 NA NA NA NA NA NA 2784 XR_003822862.2 178 48 14 287 413 NA NA NA NA NA NA 2785 XR_006392069.1 64 30 49 64 118 NA NA NA NA NA NA 2786 XM_044306791.1 147 235 165 130 138 NA NA NA NA NA NA 2787 XM_044323917.1 21 0 0 0 163 Q91X17 8.21e-32 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Mus musculus (Mouse) antibacterial innate immune response [GO:0140367]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; autophagy [GO:0006914]; calcium ion homeostasis [GO:0055074]; cellular calcium ion homeostasis [GO:0006874]; cellular chloride ion homeostasis [GO:0030644]; cellular phosphate ion homeostasis [GO:0030643]; cellular response to unfolded protein [GO:0034620]; cellular sodium ion homeostasis [GO:0006883]; chaperone-mediated protein folding [GO:0061077]; chemical homeostasis [GO:0048878]; chloride ion homeostasis [GO:0055064]; citric acid secretion [GO:0046720]; collecting duct development [GO:0072044]; connective tissue replacement [GO:0097709]; creatinine homeostasis [GO:0097273]; defense response to Gram-negative bacterium [GO:0050829]; endoplasmic reticulum organization [GO:0007029]; gene expression [GO:0010467]; glomerular filtration [GO:0003094]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; ion homeostasis [GO:0050801]; juxtaglomerular apparatus development [GO:0072051]; kidney development [GO:0001822]; leukocyte cell-cell adhesion [GO:0007159]; lipid metabolic process [GO:0006629]; loop of Henle development [GO:0072070]; metanephric ascending thin limb development [GO:0072218]; metanephric distal convoluted tubule development [GO:0072221]; metanephric thick ascending limb development [GO:0072233]; micturition [GO:0060073]; multicellular organismal homeostasis [GO:0048871]; multicellular organismal response to stress [GO:0033555]; neutrophil migration [GO:1990266]; organ or tissue specific immune response [GO:0002251]; peptidyl-threonine phosphorylation [GO:0018107]; phosphate ion homeostasis [GO:0055062]; potassium ion homeostasis [GO:0055075]; protein localization to vacuole [GO:0072665]; protein phosphorylation [GO:0006468]; protein transport into plasma membrane raft [GO:0044861]; regulation of blood pressure [GO:0008217]; regulation of protein transport [GO:0051223]; regulation of urine volume [GO:0035809]; renal sodium ion absorption [GO:0070294]; renal urate salt excretion [GO:0097744]; renal water homeostasis [GO:0003091]; response to endoplasmic reticulum stress [GO:0034976]; response to lipopolysaccharide [GO:0032496]; response to unfolded protein [GO:0006986]; response to water deprivation [GO:0009414]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; sodium ion homeostasis [GO:0055078]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; ubiquitin-dependent ERAD pathway [GO:0030433]; urate transport [GO:0015747]; urea transmembrane transport [GO:0071918]; water homeostasis [GO:0030104] GO:0000922; GO:0001822; GO:0002251; GO:0003091; GO:0003094; GO:0005201; GO:0005509; GO:0005615; GO:0005783; GO:0005794; GO:0005886; GO:0005929; GO:0006468; GO:0006629; GO:0006874; GO:0006883; GO:0006914; GO:0006915; GO:0006954; GO:0006986; GO:0007029; GO:0007157; GO:0007159; GO:0008217; GO:0008380; GO:0009410; GO:0009414; GO:0009986; GO:0010467; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0018107; GO:0019864; GO:0030104; GO:0030433; GO:0030643; GO:0030644; GO:0031410; GO:0032496; GO:0033209; GO:0033555; GO:0034620; GO:0034976; GO:0035809; GO:0044861; GO:0045121; GO:0045177; GO:0046720; GO:0048871; GO:0048878; GO:0050801; GO:0050829; GO:0051223; GO:0055062; GO:0055064; GO:0055074; GO:0055075; GO:0055078; GO:0060073; GO:0060170; GO:0061077; GO:0070294; GO:0071918; GO:0072044; GO:0072051; GO:0072070; GO:0072218; GO:0072221; GO:0072233; GO:0072665; GO:0097190; GO:0097273; GO:0097709; GO:0097744; GO:0140367; GO:1990266 2788 XM_044313001.1 0 0 0 11 0 NA NA NA NA NA NA 2789 XM_029350382.2 0 0 0 0 13 Q9DBU3 2.89e-177 Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) Mus musculus (Mouse) cellular response to dsDNA [GO:1990786]; cellular response to dsRNA [GO:0071359]; cellular response to virus [GO:0098586]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; maturation of SSU-rRNA [GO:0030490]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of MDA-5 signaling pathway [GO:0039534]; negative regulation of protein-containing complex assembly [GO:0031333]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-beta production [GO:0032728]; protein phosphorylation [GO:0006468] GO:0004674; GO:0005524; GO:0005829; GO:0006468; GO:0030490; GO:0030688; GO:0031333; GO:0032728; GO:0039534; GO:0043124; GO:0045087; GO:0045089; GO:0046872; GO:0051607; GO:0071359; GO:0089720; GO:0098586; GO:0106310; GO:1990786 2790 XM_029330226.2 112 74 89 97 103 Q8C9M2 2.26e-26 Coiled-coil domain-containing protein 15 Mus musculus (Mouse) NA GO:0005813 2791 XM_029333365.2 0 0 15 0 0 Q5PQQ9 7.77e-43 Centrosomal protein of 70 kDa (Cep70) Rattus norvegicus (Rat) cilium assembly [GO:0060271]; regulation of microtubule cytoskeleton organization [GO:0070507] GO:0005737; GO:0005813; GO:0042802; GO:0043015; GO:0060271; GO:0070507 2792 XM_029356691.2 1556 1415 1345 1884 1255 Q8BTK5 7.5e-51 SET and MYND domain-containing protein 4 (EC 2.1.1.-) Mus musculus (Mouse) heart development [GO:0007507]; methylation [GO:0032259] GO:0005634; GO:0005737; GO:0007507; GO:0008168; GO:0032259; GO:0042826; GO:0046872 2793 XM_029341554.2 47 68 30 0 83 NA NA NA NA NA NA 2794 XR_006395299.1 386 292 319 350 325 NA NA NA NA NA NA 2795 XM_029344182.2 6293 6430 4385 5883 5393 NA NA NA NA NA NA 2796 XM_044317722.1 230 210 131 199 198 NA NA NA NA NA NA 2797 XM_029334226.2 212 132 105 353 436 P05183 7e-89 Cytochrome P450 3A2 (EC 1.14.14.1) (CYPIIIA2) (Cytochrome P450-PCN2) (Cytochrome P450/6-beta-A) (Testosterone 6-beta-hydroxylase) Rattus norvegicus (Rat) alkaloid catabolic process [GO:0009822]; estrogen metabolic process [GO:0008210]; heterocycle metabolic process [GO:0046483]; lipid hydroxylation [GO:0002933]; monoterpenoid metabolic process [GO:0016098]; oxidative demethylation [GO:0070989]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]; steroid catabolic process [GO:0006706]; steroid metabolic process [GO:0008202]; vitamin D catabolic process [GO:0042369]; xenobiotic catabolic process [GO:0042178]; xenobiotic metabolic process [GO:0006805] GO:0002933; GO:0004497; GO:0005496; GO:0005506; GO:0005737; GO:0005789; GO:0006706; GO:0006805; GO:0008202; GO:0008210; GO:0008395; GO:0008401; GO:0009822; GO:0016098; GO:0016491; GO:0019899; GO:0020037; GO:0030343; GO:0032451; GO:0034875; GO:0042178; GO:0042369; GO:0042572; GO:0042573; GO:0046483; GO:0050649; GO:0062181; GO:0070330; GO:0070576; GO:0070989; GO:0101020; GO:0101021 2798 XM_029352419.2 15972 14860 9273 9895 10180 Q96LD1 6e-58 Zeta-sarcoglycan (Zeta-SG) (ZSG1) Homo sapiens (Human) cardiac muscle tissue development [GO:0048738]; heart contraction [GO:0060047]; membrane organization [GO:0061024]; muscle cell cellular homeostasis [GO:0046716]; muscle cell development [GO:0055001] GO:0005737; GO:0005856; GO:0016012; GO:0042383; GO:0046716; GO:0048738; GO:0055001; GO:0060047; GO:0061024 2799 XM_029335204.2 289 229 151 374 226 NA NA NA NA NA NA 2800 XM_044319920.1 187 30 48 167 31 NA NA NA NA NA NA 2801 XR_006397926.1 2 20 0 12 4 NA NA NA NA NA NA 2802 XM_044307807.1 0 45 3 7 28 P0DP43 6.82e-32 Cation channel sperm-associated auxiliary subunit epsilon (CatSper-epsilon) (CatSperepsilon) (C1orf101-like protein) Mus musculus (Mouse) flagellated sperm motility [GO:0030317]; sperm capacitation [GO:0048240] GO:0030317; GO:0036128; GO:0048240; GO:0097228 2803 XM_044309096.1 0 0 0 13 0 NA NA NA NA NA NA 2804 XR_006393975.1 20 0 0 53 343 NA NA NA NA NA NA 2805 XM_044320339.1 29 65 8 38 0 Q804R0 2.36e-32 Transcription factor LBX2 (Ladybird homeobox 2) (Ladybird homeobox protein homolog 2) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic axis specification [GO:0000578]; muscle cell development [GO:0055001]; muscle cell differentiation [GO:0042692]; positive regulation of convergent extension involved in gastrulation [GO:1904105]; positive regulation of non-canonical Wnt signaling pathway [GO:2000052]; posterior lateral line neuromast deposition [GO:0048922]; posterior lateral line neuromast primordium migration [GO:0048920]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000578; GO:0000981; GO:0005634; GO:0006357; GO:0042692; GO:0048920; GO:0048922; GO:0055001; GO:0060828; GO:1904105; GO:1990837; GO:2000052 2806 XR_006396152.1 13 112 0 2 135 NA NA NA NA NA NA 2807 XM_044310249.1 0 0 0 2 8 NA NA NA NA NA NA 2808 XM_044325819.1 35 11 26 67 193 NA NA NA NA NA NA 2809 XM_029325847.2 11 11 19 16 21 NA NA NA NA NA NA 2810 XM_044322133.1 179 71 18 168 7 P0DPE1 1.06e-63 EEF1A lysine methyltransferase 4 (EC 2.1.1.-) Bos taurus (Bovine) NA GO:0008168; GO:0016279 2811 XM_044309704.1 81 36 54 127 72 Q96AY4 1.86e-168 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2812 XM_044309704.1 81 36 54 127 72 Q96AY4 2.83e-135 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2813 XM_044309704.1 81 36 54 127 72 Q96AY4 4.11e-134 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2814 XM_044309704.1 81 36 54 127 72 Q96AY4 1.58e-113 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2815 XM_044309704.1 81 36 54 127 72 Q96AY4 3.46e-68 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2816 XM_044309704.1 81 36 54 127 72 Q96AY4 1.6e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2817 XM_029354534.2 33 5 11 38 35 NA NA NA NA NA NA 2818 XM_044324619.1 0 115 0 0 313 Q32LQ6 1.18e-169 Major facilitator superfamily domain-containing protein 1 Danio rerio (Zebrafish) (Brachydanio rerio) protein localization to lysosome [GO:0061462]; protein stabilization [GO:0050821] GO:0005764; GO:0005765; GO:0022857; GO:0042803; GO:0050821; GO:0061462 2819 XM_029324730.2 4906 4559 2553 4914 4925 Q9DFS6 7.28e-79 Eukaryotic translation initiation factor 4E-1A (eIF4E-1A) (mRNA cap-binding protein) Danio rerio (Zebrafish) (Brachydanio rerio) regulation of translation [GO:0006417]; translational initiation [GO:0006413] GO:0000340; GO:0003743; GO:0005634; GO:0005737; GO:0005845; GO:0006413; GO:0006417; GO:0016281 2820 XM_029355378.2 121 53 52 55 218 Q5RFG8 2.62e-26 E3 ubiquitin-protein ligase E3D (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase E3D) (UbcH10-binding protein with a HECT-like domain) (Ubiquitin-conjugating enzyme E2C-binding protein) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) protein ubiquitination [GO:0016567] GO:0005737; GO:0016567; GO:0016740 2821 XM_029332830.2 3636 2905 1908 2280 2843 A6H7H7 1.07e-103 F-box only protein 3 Bos taurus (Bovine) response to lipopolysaccharide [GO:0032496]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0005654; GO:0005737; GO:0005829; GO:0019005; GO:0031146; GO:0032496; GO:1990756 2822 XM_044323983.1 0 5 20 14 51 G3V9H8 1.26e-73 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Rattus norvegicus (Rat) cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0007156; GO:0007158; GO:0007169; GO:0007399; GO:0009410; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030182; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0098797 2823 XM_029333158.2 156 132 85 108 227 NA NA NA NA NA NA 2824 XM_029330003.2 89 100 0 29 0 Q9TTT5 1.77e-90 Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3) Oryctolagus cuniculus (Rabbit) protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0008076; GO:0030425; GO:0034765; GO:0042383; GO:0046872; GO:0051260 2825 XM_044327135.1 41 113 69 128 290 NA NA NA NA NA NA 2826 XM_029337211.2 1006 680 549 972 1025 Q9C0C9 3.81e-88 (E3-independent) E2 ubiquitin-conjugating enzyme (EC 2.3.2.24) (E2/E3 hybrid ubiquitin-protein ligase UBE2O) (Ubiquitin carrier protein O) (Ubiquitin-conjugating enzyme E2 O) (Ubiquitin-conjugating enzyme E2 of 230 kDa) (Ubiquitin-conjugating enzyme E2-230K) (Ubiquitin-protein ligase O) Homo sapiens (Human) negative regulation of apoptotic process [GO:0043066]; positive regulation of BMP signaling pathway [GO:0030513]; protein K63-linked ubiquitination [GO:0070534]; protein monoubiquitination [GO:0006513]; retrograde transport, endosome to Golgi [GO:0042147] GO:0003723; GO:0004842; GO:0004869; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006513; GO:0016604; GO:0030513; GO:0042147; GO:0043066; GO:0061630; GO:0061631; GO:0070534 2827 XM_029337211.2 1006 680 549 972 1025 Q9C0C9 1.03e-36 (E3-independent) E2 ubiquitin-conjugating enzyme (EC 2.3.2.24) (E2/E3 hybrid ubiquitin-protein ligase UBE2O) (Ubiquitin carrier protein O) (Ubiquitin-conjugating enzyme E2 O) (Ubiquitin-conjugating enzyme E2 of 230 kDa) (Ubiquitin-conjugating enzyme E2-230K) (Ubiquitin-protein ligase O) Homo sapiens (Human) negative regulation of apoptotic process [GO:0043066]; positive regulation of BMP signaling pathway [GO:0030513]; protein K63-linked ubiquitination [GO:0070534]; protein monoubiquitination [GO:0006513]; retrograde transport, endosome to Golgi [GO:0042147] GO:0003723; GO:0004842; GO:0004869; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006513; GO:0016604; GO:0030513; GO:0042147; GO:0043066; GO:0061630; GO:0061631; GO:0070534 2828 XM_029337211.2 1006 680 549 972 1025 Q9C0C9 3.93e-30 (E3-independent) E2 ubiquitin-conjugating enzyme (EC 2.3.2.24) (E2/E3 hybrid ubiquitin-protein ligase UBE2O) (Ubiquitin carrier protein O) (Ubiquitin-conjugating enzyme E2 O) (Ubiquitin-conjugating enzyme E2 of 230 kDa) (Ubiquitin-conjugating enzyme E2-230K) (Ubiquitin-protein ligase O) Homo sapiens (Human) negative regulation of apoptotic process [GO:0043066]; positive regulation of BMP signaling pathway [GO:0030513]; protein K63-linked ubiquitination [GO:0070534]; protein monoubiquitination [GO:0006513]; retrograde transport, endosome to Golgi [GO:0042147] GO:0003723; GO:0004842; GO:0004869; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006513; GO:0016604; GO:0030513; GO:0042147; GO:0043066; GO:0061630; GO:0061631; GO:0070534 2829 XM_029329089.2 7 0 8 0 7 Q9CUX1 3.88e-28 52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (THAP domain-containing protein 0) (THAP domain-containing protein 12) Mus musculus (Mouse) NA GO:0003677; GO:0005634; GO:0046872; GO:0046983 2830 XM_044310075.1 602 2 24 2 3 P70490 3.71e-50 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 2831 XM_044310075.1 602 2 24 2 3 P70490 3.55e-49 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 2832 XM_044310075.1 602 2 24 2 3 P70490 3.55e-49 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 2833 XM_044310075.1 602 2 24 2 3 P70490 3.55e-49 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 2834 XM_044310075.1 602 2 24 2 3 P70490 3.55e-49 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 2835 XM_044310075.1 602 2 24 2 3 P70490 4.05e-49 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 2836 XM_044310075.1 602 2 24 2 3 P70490 8.81e-49 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 2837 XM_044310075.1 602 2 24 2 3 P70490 1e-43 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 2838 XR_003826882.2 589 1792 414 593 358 NA NA NA NA NA NA 2839 XM_029358378.2 3119 1155 1896 2566 3065 O14776 1.71e-163 Transcription elongation regulator 1 (TATA box-binding protein-associated factor 2S) (Transcription factor CA150) Homo sapiens (Human) mRNA processing [GO:0006397]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription elongation by RNA polymerase II [GO:0034244]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; RNA splicing [GO:0008380] GO:0000122; GO:0003711; GO:0003712; GO:0003713; GO:0003714; GO:0003723; GO:0005634; GO:0005654; GO:0006397; GO:0008380; GO:0016607; GO:0032968; GO:0034244; GO:0042802; GO:0044390; GO:0045944; GO:0061629; GO:0070063 2840 XR_003828620.2 56 123 49 90 53 NA NA NA NA NA NA 2841 XM_029338368.2 78 8 65 29 166 A2AX52 6.01e-40 Collagen alpha-4(VI) chain Mus musculus (Mouse) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005518; GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0032991; GO:0062023 2842 XM_029338368.2 78 8 65 29 166 A2AX52 3.26e-25 Collagen alpha-4(VI) chain Mus musculus (Mouse) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005518; GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0032991; GO:0062023 2843 XM_029338368.2 78 8 65 29 166 A2AX52 3.16e-24 Collagen alpha-4(VI) chain Mus musculus (Mouse) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005518; GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0032991; GO:0062023 2844 XM_029331690.2 1449 845 662 1053 1193 Q8C1B2 7.38e-41 Protein mono-ADP-ribosyltransferase TIPARP (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 14) (ARTD14) (TCDD-inducible poly [ADP-ribose] polymerase) Mus musculus (Mouse) androgen metabolic process [GO:0008209]; cellular response to organic cyclic compound [GO:0071407]; estrogen metabolic process [GO:0008210]; face morphogenesis [GO:0060325]; female gonad development [GO:0008585]; hemopoiesis [GO:0030097]; kidney development [GO:0001822]; negative regulation of gene expression [GO:0010629]; nitrogen compound metabolic process [GO:0006807]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of protein catabolic process [GO:0045732]; post-embryonic development [GO:0009791]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; smooth muscle tissue development [GO:0048745]; vasculogenesis [GO:0001570] GO:0000987; GO:0001570; GO:0001822; GO:0003950; GO:0005634; GO:0006807; GO:0008209; GO:0008210; GO:0008585; GO:0009791; GO:0010629; GO:0016779; GO:0030097; GO:0045732; GO:0046872; GO:0048008; GO:0048705; GO:0048745; GO:0060021; GO:0060325; GO:0071407; GO:0140803; GO:1990404 2845 XM_044327352.1 0 5 0 6 6 NA NA NA NA NA NA 2846 XM_044317834.1 5 6 28 38 15 NA NA NA NA NA NA 2847 XM_044318373.1 513 589 667 622 1474 NA NA NA NA NA NA 2848 XM_029331628.2 1021 1339 585 682 994 Q15057 1.87e-43 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 (Centaurin-beta-2) (Cnt-b2) Homo sapiens (Human) actin filament-based process [GO:0030029]; cellular response to nerve growth factor stimulus [GO:1990090]; endocytic recycling [GO:0032456] GO:0001726; GO:0005096; GO:0010008; GO:0016020; GO:0030029; GO:0032456; GO:0046872; GO:1990090 2849 XM_044320248.1 5 4 3 0 9 P54318 1.37e-45 Pancreatic lipase-related protein 2 (PL-RP2) (Cytotoxic T lymphocyte lipase) (Galactolipase) (EC 3.1.1.26) (Secretory glycoprotein GP-3) (Triacylglycerol lipase) (EC 3.1.1.3) Rattus norvegicus (Rat) cellular defense response [GO:0006968]; galactolipid catabolic process [GO:0019376]; intestinal lipid catabolic process [GO:0044258]; lipid catabolic process [GO:0016042]; phosphatidylcholine catabolic process [GO:0034638]; phospholipid catabolic process [GO:0009395]; phospholipid metabolic process [GO:0006644]; post-embryonic development [GO:0009791]; response to bacterium [GO:0009617]; response to food [GO:0032094]; response to glucocorticoid [GO:0051384]; response to lipid [GO:0033993]; response to peptide hormone [GO:0043434]; triglyceride catabolic process [GO:0019433] GO:0004620; GO:0004806; GO:0005509; GO:0005615; GO:0006644; GO:0006968; GO:0009395; GO:0009617; GO:0009791; GO:0016042; GO:0016298; GO:0019376; GO:0019433; GO:0032094; GO:0033993; GO:0034638; GO:0042589; GO:0043005; GO:0043434; GO:0044258; GO:0047372; GO:0047714; GO:0051384; GO:0102549 2850 XR_003823856.2 74 0 0 87 82 NA NA NA NA NA NA 2851 XM_029341320.2 0 0 3 3 8 NA NA NA NA NA NA 2852 XM_044308234.1 252 570 452 207 0 Q8WV37 2.15e-48 Zinc finger protein 480 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0046872 2853 XM_044308234.1 252 570 452 207 0 Q8WV37 3.29e-41 Zinc finger protein 480 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0046872 2854 XM_044308234.1 252 570 452 207 0 Q8WV37 1.77e-40 Zinc finger protein 480 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0046872 2855 XM_044308234.1 252 570 452 207 0 Q8WV37 3.1e-40 Zinc finger protein 480 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0046872 2856 XM_044308234.1 252 570 452 207 0 Q8WV37 5.94e-39 Zinc finger protein 480 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0046872 2857 XM_044308234.1 252 570 452 207 0 Q8WV37 3.46e-34 Zinc finger protein 480 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0046872 2858 XM_044308234.1 252 570 452 207 0 Q8WV37 4.23e-33 Zinc finger protein 480 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0046872 2859 XM_044308234.1 252 570 452 207 0 Q8WV37 1.75e-26 Zinc finger protein 480 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0046872 2860 XM_029330182.2 91 34 55 294 100 NA NA NA NA NA NA 2861 XM_029355880.2 2160 1622 1267 1850 1772 A5D7H2 5.68e-147 Striatin-3 Bos taurus (Bovine) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000122; GO:0005516; GO:0005654; GO:0005737; GO:0005794; GO:0005886; GO:0030425; GO:0031267; GO:0044877; GO:0045892; GO:0045944; GO:0051721; GO:0070016; GO:0090443 2862 XM_029355880.2 2160 1622 1267 1850 1772 A5D7H2 1.31e-49 Striatin-3 Bos taurus (Bovine) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000122; GO:0005516; GO:0005654; GO:0005737; GO:0005794; GO:0005886; GO:0030425; GO:0031267; GO:0044877; GO:0045892; GO:0045944; GO:0051721; GO:0070016; GO:0090443 2863 XM_029349073.2 956 706 584 975 752 Q6ZU65 2.36e-51 Ubinuclein-2 Homo sapiens (Human) NA GO:0005615; GO:0005634; GO:0005654 2864 XM_029325812.2 4 35 12 1 2 NA NA NA NA NA NA 2865 XM_029334822.2 1068 896 624 1052 692 Q5ZIA5 0 Coatomer subunit beta (Beta-coat protein) (Beta-COP) Gallus gallus (Chicken) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886] GO:0000139; GO:0005198; GO:0005829; GO:0006886; GO:0006888; GO:0006891; GO:0030126 2866 XR_006396182.1 0 0 9 0 32 NA NA NA NA NA NA 2867 XR_006391797.1 101 151 35 34 17 NA NA NA NA NA NA 2868 XM_029336198.2 516 419 633 1252 2113 NA NA NA NA NA NA 2869 XM_029340301.2 0 0 95 0 0 Q15434 5.51e-79 RNA-binding motif, single-stranded-interacting protein 2 (Suppressor of CDC2 with RNA-binding motif 3) Homo sapiens (Human) RNA processing [GO:0006396] GO:0003723; GO:0003730; GO:0005634; GO:0005829; GO:0006396; GO:0008143; GO:0008266; GO:1990904 2870 XM_029344019.2 2718 1895 1380 2280 2358 Q9XSK2 2.18e-25 CD63 antigen (CD antigen CD63) Bos taurus (Bovine) cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; endosome to melanosome transport [GO:0035646]; pigment granule maturation [GO:0048757]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of receptor internalization [GO:0002092]; protein transport [GO:0015031]; regulation of vascular endothelial growth factor signaling pathway [GO:1900746] GO:0002092; GO:0005576; GO:0005765; GO:0005886; GO:0007160; GO:0009986; GO:0015031; GO:0016477; GO:0031902; GO:0032585; GO:0035646; GO:0042470; GO:0048757; GO:0097487; GO:1900746; GO:2001046 2871 XM_029347970.2 82 115 29 44 52 NA NA NA NA NA NA 2872 XM_029327040.2 138 0 0 0 0 Q8R4K8 0 Pappalysin-1 (EC 3.4.24.79) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase) (Pregnancy-associated plasma protein A) (PAPP-A) Mus musculus (Mouse) cell surface receptor signaling pathway [GO:0007166]; female pregnancy [GO:0007565]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to dexamethasone [GO:0071548]; response to follicle-stimulating hormone [GO:0032354] GO:0004175; GO:0004222; GO:0005576; GO:0005615; GO:0006508; GO:0007166; GO:0007565; GO:0008237; GO:0030163; GO:0032354; GO:0046872; GO:0071548 2873 XR_006391719.1 5 0 13 14 61 NA NA NA NA NA NA 2874 XM_044317753.1 864 514 550 1074 1025 Q9Y4D8 0 Probable E3 ubiquitin-protein ligase HECTD4 (EC 2.3.2.26) (HECT domain-containing protein 4) (HECT-type E3 ubiquitin transferase HECTD4) Homo sapiens (Human) glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006] GO:0004842; GO:0006006; GO:0016020; GO:0042593 2875 XM_044317753.1 864 514 550 1074 1025 Q9Y4D8 5.63e-164 Probable E3 ubiquitin-protein ligase HECTD4 (EC 2.3.2.26) (HECT domain-containing protein 4) (HECT-type E3 ubiquitin transferase HECTD4) Homo sapiens (Human) glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006] GO:0004842; GO:0006006; GO:0016020; GO:0042593 2876 XM_029335219.2 1892 1762 2406 2671 2700 Q8C080 3.12e-49 Sorting nexin-16 Mus musculus (Mouse) early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; protein targeting to lysosome [GO:0006622] GO:0005764; GO:0005769; GO:0005770; GO:0005829; GO:0006622; GO:0008333; GO:0031313; GO:0031901; GO:0031902; GO:0035091; GO:0042802; GO:0043231; GO:0045022 2877 XM_044326794.1 0 0 0 0 21 NA NA NA NA NA NA 2878 XM_044317202.1 0 0 0 0 18 NA NA NA NA NA NA 2879 XM_044312941.1 51 48 0 152 6 Q9WVM6 2.43e-37 Tolloid-like protein 2 (EC 3.4.24.-) Mus musculus (Mouse) cell differentiation [GO:0030154]; dorsal/ventral pattern formation [GO:0009953]; negative regulation of skeletal muscle tissue growth [GO:0048632]; protein processing [GO:0016485] GO:0004222; GO:0005509; GO:0005615; GO:0008270; GO:0009953; GO:0016485; GO:0030154; GO:0048632 2880 XM_044312941.1 51 48 0 152 6 Q9WVM6 1.38e-30 Tolloid-like protein 2 (EC 3.4.24.-) Mus musculus (Mouse) cell differentiation [GO:0030154]; dorsal/ventral pattern formation [GO:0009953]; negative regulation of skeletal muscle tissue growth [GO:0048632]; protein processing [GO:0016485] GO:0004222; GO:0005509; GO:0005615; GO:0008270; GO:0009953; GO:0016485; GO:0030154; GO:0048632 2881 XM_044310318.1 74 50 50 143 146 Q9NR20 2.39e-54 Dual specificity tyrosine-phosphorylation-regulated kinase 4 (EC 2.7.12.1) Homo sapiens (Human) peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107] GO:0004674; GO:0004712; GO:0004713; GO:0005524; GO:0005634; GO:0005737; GO:0005856; GO:0018105; GO:0018107; GO:0043231; GO:0046872; GO:0106310 2882 XM_044317965.1 0 25 0 8 29 NA NA NA NA NA NA 2883 XM_029340193.2 307 105 82 316 188 P46735 0 Unconventional myosin-Ib (MIH-L) (Myosin I alpha) (MMI-alpha) (MMIa) Mus musculus (Mouse) actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; actin filament-based movement [GO:0030048]; post-Golgi vesicle-mediated transport [GO:0006892]; transferrin transport [GO:0033572]; vesicle transport along actin filament [GO:0030050] GO:0000146; GO:0003774; GO:0003779; GO:0005516; GO:0005524; GO:0005546; GO:0005547; GO:0005737; GO:0005769; GO:0005884; GO:0005886; GO:0005902; GO:0005903; GO:0006892; GO:0007015; GO:0010008; GO:0015629; GO:0016459; GO:0030048; GO:0030050; GO:0030175; GO:0031982; GO:0032588; GO:0033572; GO:0045177; GO:0048471; GO:0051015; GO:0051017; GO:0071944 2884 XM_029355304.2 1691 1726 2567 2682 2086 NA NA NA NA NA NA 2885 XR_006395809.1 33 23 25 16 8 NA NA NA NA NA NA 2886 XM_029358278.2 95 61 41 48 164 A2AJ76 7.05e-30 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 2887 XM_029358278.2 95 61 41 48 164 A2AJ76 1.42e-21 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 2888 XM_029346502.2 6538 8500 4110 10545 7994 P23049 1.88e-55 Tyrosine-protein kinase transforming protein SEA (EC 2.7.10.2) Avian erythroblastosis virus (strain S13) NA GO:0004715; GO:0005524 2889 XR_006394803.1 54 0 0 0 0 NA NA NA NA NA NA 2890 XM_044315454.1 22 0 52 30 201 P14381 5.32e-97 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 2891 XR_006392971.1 41 2 25 5 151 NA NA NA NA NA NA 2892 XM_029324840.2 0 0 0 0 10 NA NA NA NA NA NA 2893 XR_006392715.1 0 0 19 9 117 Q09575 7.39e-29 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 2894 XM_044313156.1 56 27 23 80 93 A2AJ76 4e-72 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 2895 XM_044313156.1 56 27 23 80 93 A2AJ76 1.22e-63 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 2896 XM_044313156.1 56 27 23 80 93 A2AJ76 2.8e-63 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 2897 XM_044313156.1 56 27 23 80 93 A2AJ76 7.8e-62 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 2898 XM_044313156.1 56 27 23 80 93 A2AJ76 2.86e-58 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 2899 XM_044313156.1 56 27 23 80 93 A2AJ76 3.9e-55 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 2900 XM_044313156.1 56 27 23 80 93 A2AJ76 8.58e-50 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 2901 XM_044313156.1 56 27 23 80 93 A2AJ76 1.02e-49 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 2902 XM_044313156.1 56 27 23 80 93 A2AJ76 4.3e-47 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 2903 XM_044313156.1 56 27 23 80 93 A2AJ76 2.26e-46 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 2904 XM_044313156.1 56 27 23 80 93 A2AJ76 2.3e-46 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 2905 XM_044313156.1 56 27 23 80 93 A2AJ76 1.74e-43 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 2906 XM_044313156.1 56 27 23 80 93 A2AJ76 2.13e-43 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 2907 XM_044313156.1 56 27 23 80 93 A2AJ76 2.84e-34 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 2908 XM_044313156.1 56 27 23 80 93 A2AJ76 2.17e-27 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 2909 XR_006392883.1 41 2 25 5 151 NA NA NA NA NA NA 2910 XM_029356416.2 3031 3566 2466 4710 3904 Q5S1U6 7.78e-92 Interferon-related developmental regulator 1 Sus scrofa (Pig) cell differentiation [GO:0030154] GO:0005634; GO:0030154 2911 XM_029341401.2 285 205 189 203 344 NA NA NA NA NA NA 2912 XM_029330421.2 0 0 7 0 11 Q9EQD2 9.02e-38 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 2913 XM_029339063.2 854 175 413 312 705 P25286 0 V-type proton ATPase 116 kDa subunit a 1 (V-ATPase 116 kDa subunit a 1) (Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit) (Vacuolar adenosine triphosphatase subunit Ac116) (Vacuolar proton pump subunit 1) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1) Rattus norvegicus (Rat) regulation of macroautophagy [GO:0016241]; synaptic vesicle lumen acidification [GO:0097401]; toxin transport [GO:1901998]; vacuolar acidification [GO:0007035] GO:0000220; GO:0005737; GO:0005886; GO:0007035; GO:0008021; GO:0016020; GO:0016241; GO:0016471; GO:0030665; GO:0030672; GO:0042470; GO:0043195; GO:0043229; GO:0046961; GO:0048471; GO:0051117; GO:0097401; GO:1901998 2914 XM_044310135.1 243 39 124 110 60 Q9Y6N7 7.28e-31 Roundabout homolog 1 (Deleted in U twenty twenty) (H-Robo-1) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; axon midline choice point recognition [GO:0016199]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; endocardial cushion formation [GO:0003272]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of gene expression [GO:0010629]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; negative regulation of negative chemotaxis [GO:0050925]; nervous system development [GO:0007399]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; pulmonary valve morphogenesis [GO:0003184]; Roundabout signaling pathway [GO:0035385]; ventricular septum morphogenesis [GO:0060412] GO:0002042; GO:0003148; GO:0003180; GO:0003184; GO:0003272; GO:0005737; GO:0005886; GO:0006919; GO:0007155; GO:0007156; GO:0007399; GO:0008046; GO:0009986; GO:0010628; GO:0010629; GO:0016199; GO:0021836; GO:0030275; GO:0030336; GO:0030424; GO:0033116; GO:0033600; GO:0035025; GO:0035385; GO:0035481; GO:0035904; GO:0042802; GO:0043406; GO:0050772; GO:0050925; GO:0060412; GO:0070100; GO:1900748 2915 XM_044310135.1 243 39 124 110 60 Q9Y6N7 1.29e-21 Roundabout homolog 1 (Deleted in U twenty twenty) (H-Robo-1) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; axon midline choice point recognition [GO:0016199]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; endocardial cushion formation [GO:0003272]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of gene expression [GO:0010629]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; negative regulation of negative chemotaxis [GO:0050925]; nervous system development [GO:0007399]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; pulmonary valve morphogenesis [GO:0003184]; Roundabout signaling pathway [GO:0035385]; ventricular septum morphogenesis [GO:0060412] GO:0002042; GO:0003148; GO:0003180; GO:0003184; GO:0003272; GO:0005737; GO:0005886; GO:0006919; GO:0007155; GO:0007156; GO:0007399; GO:0008046; GO:0009986; GO:0010628; GO:0010629; GO:0016199; GO:0021836; GO:0030275; GO:0030336; GO:0030424; GO:0033116; GO:0033600; GO:0035025; GO:0035385; GO:0035481; GO:0035904; GO:0042802; GO:0043406; GO:0050772; GO:0050925; GO:0060412; GO:0070100; GO:1900748 2916 XM_044310135.1 243 39 124 110 60 Q9Y6N7 9.01e-21 Roundabout homolog 1 (Deleted in U twenty twenty) (H-Robo-1) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; axon midline choice point recognition [GO:0016199]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; endocardial cushion formation [GO:0003272]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of gene expression [GO:0010629]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; negative regulation of negative chemotaxis [GO:0050925]; nervous system development [GO:0007399]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; pulmonary valve morphogenesis [GO:0003184]; Roundabout signaling pathway [GO:0035385]; ventricular septum morphogenesis [GO:0060412] GO:0002042; GO:0003148; GO:0003180; GO:0003184; GO:0003272; GO:0005737; GO:0005886; GO:0006919; GO:0007155; GO:0007156; GO:0007399; GO:0008046; GO:0009986; GO:0010628; GO:0010629; GO:0016199; GO:0021836; GO:0030275; GO:0030336; GO:0030424; GO:0033116; GO:0033600; GO:0035025; GO:0035385; GO:0035481; GO:0035904; GO:0042802; GO:0043406; GO:0050772; GO:0050925; GO:0060412; GO:0070100; GO:1900748 2917 XM_029341064.2 688 714 512 699 406 P00491 1.99e-102 Purine nucleoside phosphorylase (PNP) (EC 2.4.2.1) (Inosine phosphorylase) (Inosine-guanosine phosphorylase) Homo sapiens (Human) allantoin metabolic process [GO:0000255]; dAMP catabolic process [GO:0046059]; deoxyadenosine catabolic process [GO:0006157]; deoxyinosine catabolic process [GO:0006149]; immune response [GO:0006955]; IMP catabolic process [GO:0006204]; inosine catabolic process [GO:0006148]; nicotinamide riboside catabolic process [GO:0006738]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide biosynthetic process [GO:0009165]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of T cell proliferation [GO:0042102]; purine ribonucleoside salvage [GO:0006166]; purine-containing compound salvage [GO:0043101]; response to xenobiotic stimulus [GO:0009410]; urate biosynthetic process [GO:0034418] GO:0000255; GO:0001882; GO:0002060; GO:0004731; GO:0005576; GO:0005634; GO:0005737; GO:0005829; GO:0006139; GO:0006148; GO:0006149; GO:0006157; GO:0006166; GO:0006204; GO:0006738; GO:0006955; GO:0009165; GO:0009410; GO:0032743; GO:0034418; GO:0034774; GO:0042102; GO:0042301; GO:0042802; GO:0043101; GO:0046059; GO:0046638; GO:0047975; GO:0070062; GO:1904813 2918 XM_029350823.2 1761 1707 937 2050 2236 Q5MPA9 1.56e-172 Serine/threonine-protein kinase DCLK2 (EC 2.7.11.1) (CaMK-like CREB regulatory kinase 2) (CL2) (CLICK-II) (CLICK2) (Doublecortin-like and CAM kinase-like 2) (Doublecortin-like kinase 2) Rattus norvegicus (Rat) hippocampus development [GO:0021766]; intracellular signal transduction [GO:0035556]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of protein localization to nucleus [GO:1900181]; peptidyl-serine phosphorylation [GO:0018105]; protein localization to nucleus [GO:0034504]; pyramidal neuron development [GO:0021860] GO:0000226; GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0005856; GO:0008017; GO:0018105; GO:0021766; GO:0021860; GO:0034504; GO:0035556; GO:0106310; GO:1900181 2919 XM_044328570.1 41 0 248 242 443 Q4R550 0 Cysteine--tRNA ligase, cytoplasmic (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) cysteinyl-tRNA aminoacylation [GO:0006423] GO:0000049; GO:0004817; GO:0005524; GO:0005737; GO:0006423; GO:0046872 2920 XM_029354851.2 1 32 8 8 0 Q8N6U8 5.6e-23 G-protein coupled receptor 161 (G-protein coupled receptor RE2) Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:1901621] GO:0004930; GO:0005929; GO:0007186; GO:0007189; GO:0030666; GO:0043005; GO:0055037; GO:0060170; GO:0097386; GO:1901621 2921 XM_029331729.2 7718 9525 8063 10983 6512 O18405 2.53e-96 Surfeit locus protein 4 homolog Drosophila melanogaster (Fruit fly) Golgi organization [GO:0007030]; protein transport [GO:0015031] GO:0005783; GO:0005789; GO:0005793; GO:0007030; GO:0012505; GO:0015031; GO:0045169 2922 XM_044322260.1 18 23 13 25 8 NA NA NA NA NA NA 2923 XM_044328332.1 1063 743 2029 2531 5229 NA NA NA NA NA NA 2924 XM_044322011.1 5 35 1 55 141 Q9P2N4 8.12e-30 A disintegrin and metalloproteinase with thrombospondin motifs 9 (ADAM-TS 9) (ADAM-TS9) (ADAMTS-9) (EC 3.4.24.-) Homo sapiens (Human) aorta morphogenesis [GO:0035909]; endothelial cell-matrix adhesion [GO:0090673]; extracellular matrix organization [GO:0030198]; heart valve morphogenesis [GO:0003179]; melanocyte differentiation [GO:0030318]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of sprouting angiogenesis [GO:1903671]; positive regulation of melanocyte differentiation [GO:0045636]; protein transport [GO:0015031]; proteolysis [GO:0006508]; response to bacterium [GO:0009617]; ventricular cardiac muscle tissue development [GO:0003229]; vesicle-mediated transport [GO:0016192] GO:0003179; GO:0003229; GO:0004222; GO:0005615; GO:0005783; GO:0006508; GO:0008237; GO:0008270; GO:0009617; GO:0009986; GO:0010596; GO:0015031; GO:0016192; GO:0030198; GO:0030318; GO:0031012; GO:0035909; GO:0043231; GO:0045636; GO:0090673; GO:1903671 2925 XM_044308333.1 0 0 0 579 20 A2A9C3 0 KICSTOR complex protein SZT2 (Seizure threshold 2 protein) (Transcript increased in glutamate resistance) (TIGR) Mus musculus (Mouse) cellular response to amino acid starvation [GO:0034198]; cellular response to glucose starvation [GO:0042149]; central nervous system development [GO:0007417]; corpus callosum morphogenesis [GO:0021540]; negative regulation of TORC1 signaling [GO:1904262]; pigmentation [GO:0043473]; post-embryonic development [GO:0009791]; protein localization to lysosome [GO:0061462]; regulation of superoxide dismutase activity [GO:1901668]; response to nutrient levels [GO:0031667] GO:0005765; GO:0005777; GO:0007417; GO:0009791; GO:0021540; GO:0031667; GO:0034198; GO:0042149; GO:0043473; GO:0061462; GO:0061700; GO:0140007; GO:1901668; GO:1904262; GO:1990130 2926 XM_044308333.1 0 0 0 579 20 A2A9C3 5.59e-91 KICSTOR complex protein SZT2 (Seizure threshold 2 protein) (Transcript increased in glutamate resistance) (TIGR) Mus musculus (Mouse) cellular response to amino acid starvation [GO:0034198]; cellular response to glucose starvation [GO:0042149]; central nervous system development [GO:0007417]; corpus callosum morphogenesis [GO:0021540]; negative regulation of TORC1 signaling [GO:1904262]; pigmentation [GO:0043473]; post-embryonic development [GO:0009791]; protein localization to lysosome [GO:0061462]; regulation of superoxide dismutase activity [GO:1901668]; response to nutrient levels [GO:0031667] GO:0005765; GO:0005777; GO:0007417; GO:0009791; GO:0021540; GO:0031667; GO:0034198; GO:0042149; GO:0043473; GO:0061462; GO:0061700; GO:0140007; GO:1901668; GO:1904262; GO:1990130 2927 XM_044308333.1 0 0 0 579 20 A2A9C3 1.05e-59 KICSTOR complex protein SZT2 (Seizure threshold 2 protein) (Transcript increased in glutamate resistance) (TIGR) Mus musculus (Mouse) cellular response to amino acid starvation [GO:0034198]; cellular response to glucose starvation [GO:0042149]; central nervous system development [GO:0007417]; corpus callosum morphogenesis [GO:0021540]; negative regulation of TORC1 signaling [GO:1904262]; pigmentation [GO:0043473]; post-embryonic development [GO:0009791]; protein localization to lysosome [GO:0061462]; regulation of superoxide dismutase activity [GO:1901668]; response to nutrient levels [GO:0031667] GO:0005765; GO:0005777; GO:0007417; GO:0009791; GO:0021540; GO:0031667; GO:0034198; GO:0042149; GO:0043473; GO:0061462; GO:0061700; GO:0140007; GO:1901668; GO:1904262; GO:1990130 2928 XM_029348482.2 524 193 206 898 693 Q9ES07 3.9e-127 Solute carrier family 15 member 2 (Kidney H(+)/peptide cotransporter) (Oligopeptide transporter, kidney isoform) (Peptide transporter 2) Mus musculus (Mouse) dipeptide import across plasma membrane [GO:0140206]; dipeptide transport [GO:0042938]; innate immune response [GO:0045087]; oligopeptide transport [GO:0006857]; peptidoglycan transport [GO:0015835]; protein transport [GO:0015031]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424]; renal absorption [GO:0070293]; transmembrane transport [GO:0055085]; xenobiotic transport [GO:0042908] GO:0005886; GO:0006857; GO:0015031; GO:0015333; GO:0015334; GO:0015835; GO:0016020; GO:0016324; GO:0022857; GO:0042908; GO:0042938; GO:0045087; GO:0055085; GO:0070293; GO:0070424; GO:0071916; GO:0140206 2929 XR_003825252.2 13 2 34 4 99 NA NA NA NA NA NA 2930 XM_029341342.2 129 64 92 99 89 Q9QZE7 1.02e-70 Translin-associated protein X (Translin-associated factor X) Mus musculus (Mouse) cell differentiation [GO:0030154]; siRNA processing [GO:0030422]; spermatogenesis [GO:0007283] GO:0003697; GO:0003723; GO:0004521; GO:0005634; GO:0005654; GO:0005737; GO:0005794; GO:0007283; GO:0030154; GO:0030422; GO:0031687; GO:0043565; GO:0044877; GO:0046872; GO:0048471; GO:1902555 2931 XM_044323705.1 4 16 0 53 4 NA NA NA NA NA NA 2932 XM_029356654.2 202 19 93 150 140 NA NA NA NA NA NA 2933 XM_044327150.1 83 0 145 175 561 B8VIW9 0 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 2934 XR_006394929.1 371 365 382 355 514 NA NA NA NA NA NA 2935 XM_029349573.2 666 324 401 559 547 NA NA NA NA NA NA 2936 XM_029341310.2 794 1074 501 773 760 Q9D820 4.4e-51 Prolyl-tRNA synthetase associated domain-containing protein 1 (PrdX deacylase domain-containing protein 1) Mus musculus (Mouse) NA GO:0002161 2937 XM_044328450.1 9 0 27 19 18 O43299 4.23e-86 AP-5 complex subunit zeta-1 (Adaptor-related protein complex 5 zeta subunit) (Zeta5) Homo sapiens (Human) double-strand break repair via homologous recombination [GO:0000724]; endosomal transport [GO:0016197]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] GO:0000724; GO:0005634; GO:0005654; GO:0005737; GO:0005770; GO:0015031; GO:0016192; GO:0016197; GO:0016607; GO:0030119; GO:0044599 2938 XM_029353539.2 12 2 6 8 3 Q12950 8.78e-27 Forkhead box protein D4 (Forkhead-related protein FKHL9) (Forkhead-related transcription factor 5) (FREAC-5) (Myeloid factor-alpha) Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000785; GO:0000978; GO:0000981; GO:0003700; GO:0005634; GO:0006357; GO:0008301; GO:0009653; GO:0030154; GO:0043565 2939 XM_029343192.2 75 68 98 147 74 NA NA NA NA NA NA 2940 XM_044307778.1 0 6 0 9 9 NA NA NA NA NA NA 2941 XM_029351865.2 1150 1053 1005 1096 842 E7F590 0 Vacuolar protein sorting-associated protein 41 homolog Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to starvation [GO:0009267]; endosomal vesicle fusion [GO:0034058]; endosome to lysosome transport [GO:0008333]; macroautophagy [GO:0016236]; protein targeting to vacuole [GO:0006623] GO:0005765; GO:0005770; GO:0005794; GO:0005829; GO:0006623; GO:0008333; GO:0009267; GO:0016236; GO:0030136; GO:0030897; GO:0031901; GO:0031902; GO:0034058; GO:0046872 2942 XM_029336390.2 0 0 4 0 88 P16273 1.24e-36 Pathogen-related protein Hordeum vulgare (Barley) defense response [GO:0006952]; response to biotic stimulus [GO:0009607] GO:0006952; GO:0009607 2943 XM_029348778.2 350 411 364 402 445 Q90673 2.99e-49 PRELI domain-containing protein 1, mitochondrial (Px19-like protein) Gallus gallus (Chicken) apoptotic process [GO:0006915]; lipid transport [GO:0006869] GO:0005739; GO:0005758; GO:0006869; GO:0006915 2944 XM_044321045.1 0 22 0 0 59 NA NA NA NA NA NA 2945 XM_044310086.1 0 35 49 71 15 P34410 1.91e-24 TWiK family of potassium channels protein 7 Caenorhabditis elegans potassium ion transmembrane transport [GO:0071805]; stabilization of membrane potential [GO:0030322] GO:0005886; GO:0015271; GO:0022841; GO:0030322; GO:0071805 2946 XR_006392145.1 0 0 0 7 4 NA NA NA NA NA NA 2947 XM_029343395.2 727 320 358 658 579 Q17QM4 2.17e-97 Ethanolaminephosphotransferase 1 (EC 2.7.8.1) (Selenoprotein I) (SelI) Bos taurus (Bovine) phosphatidylethanolamine biosynthetic process [GO:0006646] GO:0004307; GO:0005789; GO:0005794; GO:0006646; GO:0046872 2948 XR_003824852.2 220 96 94 223 253 NA NA NA NA NA NA 2949 XM_029342832.2 1272 562 1122 1321 1659 P41777 6.75e-29 Nucleolar and coiled-body phosphoprotein 1 (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar 130 kDa protein) (Nucleolar phosphoprotein p130) Rattus norvegicus (Rat) axonogenesis [GO:0007409]; box H/ACA RNA metabolic process [GO:0033979]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; nucleolus organization [GO:0007000]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of protein import into nucleus [GO:0042306]; regulation of synaptic plasticity [GO:0048167]; regulation of translation [GO:0006417]; response to osmotic stress [GO:0006970] GO:0001093; GO:0001650; GO:0005524; GO:0005525; GO:0005654; GO:0005730; GO:0005737; GO:0006417; GO:0006970; GO:0007000; GO:0007409; GO:0008139; GO:0008284; GO:0014029; GO:0014032; GO:0015030; GO:0019904; GO:0030674; GO:0031428; GO:0031429; GO:0033979; GO:0034512; GO:0034513; GO:0042306; GO:0045893; GO:0046982; GO:0048167; GO:0062064; GO:0062065; GO:0140678 2950 XM_044327101.1 1782 3078 1023 1796 838 NA NA NA NA NA NA 2951 XM_044309890.1 330 46 31 557 506 NA NA NA NA NA NA 2952 XM_029344695.2 2045 2191 1553 1837 2075 Q53S33 1.67e-22 BolA-like protein 3 Homo sapiens (Human) cell redox homeostasis [GO:0045454]; iron ion homeostasis [GO:0055072]; iron-sulfur cluster assembly [GO:0016226]; protein maturation by [4Fe-4S] cluster transfer [GO:0106035] GO:0005739; GO:0005759; GO:0005829; GO:0016226; GO:0016604; GO:0045454; GO:0055072; GO:0106035; GO:1990229 2953 XM_044316506.1 620 322 378 764 635 NA NA NA NA NA NA 2954 XM_044310178.1 31 3 8 87 56 P0CT39 4.94e-91 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 2955 XM_044326146.1 0 0 5 0 14 NA NA NA NA NA NA 2956 XM_044308729.1 37 0 21 0 27 NA NA NA NA NA NA 2957 XR_006396723.1 55 87 43 47 95 NA NA NA NA NA NA 2958 XM_029347199.2 58 35 39 52 69 NA NA NA NA NA NA 2959 XM_029341856.2 0 0 0 105 0 NA NA NA NA NA NA 2960 XM_044327086.1 23 9 32 12 27 NA NA NA NA NA NA 2961 XM_029345399.2 1702 1396 1210 1592 1302 Q6IZ48 1.1e-32 Transcription factor Sox-8 Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon nigroviridis) NA GO:0003677; GO:0005634 2962 XM_044310697.1 0 0 0 81 0 B3EWZ8 1.23e-24 Ectin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 2963 XM_029349543.2 730 674 452 560 656 Q1LZH1 1.86e-39 Mitochondrial amidoxime reducing component 2 (mARC2) (EC 1.7.-.-) (Molybdenum cofactor sulfurase C-terminal domain-containing protein 2) (MOSC domain-containing protein 2) (Moco sulfurase C-terminal domain-containing protein 2) Bos taurus (Bovine) cellular detoxification of nitrogen compound [GO:0070458]; nitrate metabolic process [GO:0042126]; nitric oxide biosynthetic process [GO:0006809] GO:0005741; GO:0005777; GO:0006809; GO:0008940; GO:0030151; GO:0030170; GO:0042126; GO:0043546; GO:0070458; GO:0098809 2964 XM_044323088.1 407 526 278 359 1106 Q5REM3 1.6e-53 Suppressor of SWI4 1 homolog (Ssf-1) (Peter Pan homolog) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) rRNA processing [GO:0006364] GO:0005730; GO:0006364; GO:0019843 2965 XR_006394844.1 217 760 1122 415 869 A1ZAY1 8.65e-23 SH3 domain-containing protein Dlish (Dachs ligand with SH3 domains) Drosophila melanogaster (Fruit fly) establishment of epithelial cell planar polarity [GO:0090163]; establishment of planar polarity [GO:0001736]; negative regulation of hippo signaling [GO:0035331]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein localization involved in establishment of planar polarity [GO:0090251] GO:0001736; GO:0005737; GO:0005929; GO:0016327; GO:0032436; GO:0035331; GO:0045179; GO:0045296; GO:0090163; GO:0090251; GO:0120219 2966 XM_044310107.1 175 0 0 0 145 NA NA NA NA NA NA 2967 XM_044312921.1 6445 1366 1000 4395 309 P34334 1.25e-51 60S ribosomal protein L21 Caenorhabditis elegans translation [GO:0006412] GO:0003735; GO:0006412; GO:0022625 2968 XM_029357537.2 1008 2037 583 800 636 Q05AV1 4.08e-31 COMM domain-containing protein 6 Xenopus laevis (African clawed frog) NA GO:0005634; GO:0005737 2969 XM_029325255.2 17 59 4 31 152 F8J3H2 1.79e-21 NA NA NA NA 2970 XM_044319498.1 82 24 32 19 198 NA NA NA NA NA NA 2971 XM_044324966.1 0 0 4 0 20 P48454 6.14e-87 Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform (EC 3.1.3.16) (CAM-PRP catalytic subunit) (Calcineurin, testis-specific catalytic subunit) (Calmodulin-dependent calcineurin A subunit gamma isoform) Homo sapiens (Human) brain development [GO:0007420]; calcineurin-mediated signaling [GO:0097720]; calcineurin-NFAT signaling cascade [GO:0033173]; negative regulation of calcium ion import across plasma membrane [GO:1905949]; negative regulation of voltage-gated calcium channel activity [GO:1901386]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of calcium ion import across plasma membrane [GO:1905665]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; protein dephosphorylation [GO:0006470] GO:0004723; GO:0005516; GO:0005737; GO:0005739; GO:0005829; GO:0005955; GO:0006470; GO:0007420; GO:0008287; GO:0017018; GO:0033173; GO:0033192; GO:0046872; GO:0070886; GO:0097720; GO:0098793; GO:0098978; GO:1900244; GO:1901386; GO:1901387; GO:1905665; GO:1905949 2972 XR_006396782.1 0 14 0 44 7 NA NA NA NA NA NA 2973 XM_029335064.2 1682 1242 715 1203 1366 NA NA NA NA NA NA 2974 XM_044327842.1 61 44 30 86 208 NA NA NA NA NA NA 2975 XM_029334470.2 2 172 0 0 236 Q6DKN2 1.27e-31 Homeobox protein OTX2-B (xOTX2-B) (Orthodenticle 2-B) (Orthodenticle-A-like protein B) Xenopus laevis (African clawed frog) NA GO:0000981; GO:0003677; GO:0005634 2976 XM_029345526.2 178 157 101 350 291 A5D8R3 2.55e-24 Transcription factor Sox-17-beta.3 (SRY (sex determining region Y)-box 17-beta.3) Xenopus laevis (African clawed frog) gastrulation [GO:0007369]; Wnt signaling pathway [GO:0016055] GO:0003677; GO:0005634; GO:0007369; GO:0016055 2977 XM_044326386.1 397 206 218 108 421 Q90413 4.91e-74 Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) Danio rerio (Zebrafish) (Brachydanio rerio) fibroblast growth factor receptor signaling pathway [GO:0008543]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of kinase activity [GO:0033674]; regulation of bile acid biosynthetic process [GO:0070857]; regulation of hematopoietic stem cell differentiation [GO:1902036]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0004714; GO:0005007; GO:0005524; GO:0005768; GO:0005783; GO:0005886; GO:0007169; GO:0008543; GO:0017134; GO:0033674; GO:0043235; GO:0070374; GO:0070857; GO:1902036 2978 XM_044307652.1 246 121 0 0 0 Q03146 1.12e-99 Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (Protein-tyrosine kinase MPK-6) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a) Mus musculus (Mouse) axon development [GO:0061564]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell population proliferation [GO:0008283]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; ear development [GO:0043583]; embryo implantation [GO:0007566]; lactation [GO:0007595]; mammary gland alveolus development [GO:0060749]; negative regulation of cell population proliferation [GO:0008285]; neuron projection extension [GO:1990138]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of kinase activity [GO:0033674]; protein autophosphorylation [GO:0046777]; regulation of cell growth [GO:0001558]; regulation of cell-matrix adhesion [GO:0001952]; regulation of extracellular matrix disassembly [GO:0010715]; smooth muscle cell migration [GO:0014909]; smooth muscle cell-matrix adhesion [GO:0061302]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing, spreading of cells [GO:0044319] GO:0001558; GO:0001952; GO:0004714; GO:0005518; GO:0005524; GO:0005737; GO:0005886; GO:0005903; GO:0007169; GO:0007566; GO:0007595; GO:0008283; GO:0008285; GO:0010715; GO:0014909; GO:0016323; GO:0018108; GO:0033674; GO:0038062; GO:0038063; GO:0038083; GO:0043235; GO:0043583; GO:0044319; GO:0046777; GO:0046872; GO:0060444; GO:0060749; GO:0061302; GO:0061564; GO:1990138 2979 XM_044307652.1 246 121 0 0 0 Q03146 1.26e-26 Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (Protein-tyrosine kinase MPK-6) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a) Mus musculus (Mouse) axon development [GO:0061564]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell population proliferation [GO:0008283]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; ear development [GO:0043583]; embryo implantation [GO:0007566]; lactation [GO:0007595]; mammary gland alveolus development [GO:0060749]; negative regulation of cell population proliferation [GO:0008285]; neuron projection extension [GO:1990138]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of kinase activity [GO:0033674]; protein autophosphorylation [GO:0046777]; regulation of cell growth [GO:0001558]; regulation of cell-matrix adhesion [GO:0001952]; regulation of extracellular matrix disassembly [GO:0010715]; smooth muscle cell migration [GO:0014909]; smooth muscle cell-matrix adhesion [GO:0061302]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing, spreading of cells [GO:0044319] GO:0001558; GO:0001952; GO:0004714; GO:0005518; GO:0005524; GO:0005737; GO:0005886; GO:0005903; GO:0007169; GO:0007566; GO:0007595; GO:0008283; GO:0008285; GO:0010715; GO:0014909; GO:0016323; GO:0018108; GO:0033674; GO:0038062; GO:0038063; GO:0038083; GO:0043235; GO:0043583; GO:0044319; GO:0046777; GO:0046872; GO:0060444; GO:0060749; GO:0061302; GO:0061564; GO:1990138 2980 XM_029358331.2 1170 1077 504 855 661 Q9Z2F6 5.07e-48 B-cell lymphoma 3 protein homolog (BCL-3) Mus musculus (Mouse) antimicrobial humoral response [GO:0019730]; cellular response to DNA damage stimulus [GO:0006974]; defense response to bacterium [GO:0042742]; defense response to protozoan [GO:0042832]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; extracellular matrix organization [GO:0030198]; follicular dendritic cell differentiation [GO:0002268]; germinal center formation [GO:0002467]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; marginal zone B cell differentiation [GO:0002315]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of T cell apoptotic process [GO:0070233]; negative regulation of tumor necrosis factor production [GO:0032720]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translation [GO:0045727]; positive regulation of type II interferon production [GO:0032729]; protein import into nucleus [GO:0006606]; regulation of apoptotic process [GO:0042981]; regulation of DNA binding [GO:0051101]; regulation of NIK/NF-kappaB signaling [GO:1901222]; response to UV-C [GO:0010225]; response to virus [GO:0009615]; spleen development [GO:0048536]; T cell apoptotic process [GO:0070231]; T-helper 1 type immune response [GO:0042088]; T-helper 2 cell differentiation [GO:0045064] GO:0002268; GO:0002315; GO:0002455; GO:0002467; GO:0003713; GO:0003714; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0006606; GO:0006974; GO:0007249; GO:0009615; GO:0010225; GO:0019730; GO:0030198; GO:0030330; GO:0030496; GO:0030674; GO:0032088; GO:0032717; GO:0032720; GO:0032729; GO:0032733; GO:0032991; GO:0032996; GO:0033257; GO:0042088; GO:0042742; GO:0042771; GO:0042826; GO:0042832; GO:0042981; GO:0043066; GO:0043231; GO:0045064; GO:0045727; GO:0045892; GO:0045893; GO:0045944; GO:0046426; GO:0048471; GO:0048536; GO:0051101; GO:0070231; GO:0070233; GO:0140297; GO:1901222 2981 XM_044328682.1 59 4 5 79 58 P16065 0 Speract receptor (EC 4.6.1.2) (Guanylate cyclase) Strongylocentrotus purpuratus (Purple sea urchin) cGMP biosynthetic process [GO:0006182]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]; receptor guanylyl cyclase signaling pathway [GO:0007168]; signal transduction [GO:0007165] GO:0001653; GO:0004383; GO:0004672; GO:0005524; GO:0005525; GO:0005886; GO:0006182; GO:0006468; GO:0007165; GO:0007168; GO:0035556 2982 XM_029337939.2 210 261 207 59 35 NA NA NA NA NA NA 2983 XM_029348850.2 102 52 53 79 85 NA NA NA NA NA NA 2984 XR_006394111.1 0 5 10 5 8 NA NA NA NA NA NA 2985 XM_029331283.2 573 398 352 604 494 Q05C16 1.38e-64 Leucine-rich repeat-containing protein 63 Homo sapiens (Human) NA NA 2986 XM_044307556.1 6376 2068 3003 1205 1279 NA NA NA NA NA NA 2987 XR_006396235.1 20 0 5 17 0 NA NA NA NA NA NA 2988 XM_029339203.2 941 730 463 1208 655 Q8IYT3 3.2e-102 Coiled-coil domain-containing protein 170 Homo sapiens (Human) microtubule cytoskeleton organization [GO:0000226] GO:0000226; GO:0005794; GO:0008017; GO:0036064 2989 XM_029342447.2 2355 1484 972 2575 1355 NA NA NA NA NA NA 2990 XM_029336487.2 1114 910 456 842 892 NA NA NA NA NA NA 2991 XM_044326413.1 446 150 231 470 561 Q8CB44 2.12e-55 GRAM domain-containing protein 4 (Death-inducing protein) Mus musculus (Mouse) apoptotic process [GO:0006915]; negative regulation of toll-like receptor 9 signaling pathway [GO:0034164]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280] GO:0005739; GO:0005789; GO:0006915; GO:0031966; GO:0034164; GO:0043280 2992 XM_029330046.2 52 97 104 246 254 Q14155 7.19e-152 Rho guanine nucleotide exchange factor 7 (Beta-Pix) (COOL-1) (PAK-interacting exchange factor beta) (p85) Homo sapiens (Human) ephrin receptor signaling pathway [GO:0048013]; focal adhesion assembly [GO:0048041]; Golgi organization [GO:0007030]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; negative regulation of microtubule nucleation [GO:1905833]; nervous system development [GO:0007399]; positive regulation of apoptotic process [GO:0043065]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of GTPase activity [GO:0043547]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of GTP binding [GO:1904424]; signal transduction [GO:0007165] GO:0001726; GO:0005085; GO:0005737; GO:0005813; GO:0005829; GO:0005925; GO:0005938; GO:0007030; GO:0007165; GO:0007399; GO:0010763; GO:0019901; GO:0030027; GO:0030032; GO:0032991; GO:0035556; GO:0043005; GO:0043015; GO:0043025; GO:0043065; GO:0043547; GO:0048013; GO:0048041; GO:0097431; GO:0098794; GO:1900026; GO:1904424; GO:1905833; GO:2000394 2993 XR_003827346.2 4 24 13 1 13 NA NA NA NA NA NA 2994 XM_044314788.1 188 17 238 109 648 NA NA NA NA NA NA 2995 XM_044312194.1 97 2 69 192 310 NA NA NA NA NA NA 2996 XM_029330429.2 18209 23246 11992 17281 9976 P0C276 2.42e-83 Ubiquitin-60S ribosomal protein L40 (Ubiquitin A-52 residue ribosomal protein fusion product 1) [Cleaved into: Ubiquitin; 60S ribosomal protein L40 (CEP52)] Ovis aries (Sheep) translation [GO:0006412] GO:0003735; GO:0005634; GO:0005737; GO:0005840; GO:0006412; GO:1990904 2997 XR_006394072.1 9 1 10 7 67 NA NA NA NA NA NA 2998 XM_044325933.1 4 0 0 0 12 NA NA NA NA NA NA 2999 XM_044311317.1 1008 734 571 883 1037 NA NA NA NA NA NA 3000 XR_006392593.1 55 10 62 38 262 NA NA NA NA NA NA 3001 XM_029358252.2 216 135 131 248 195 NA NA NA NA NA NA 3002 XM_029329874.2 1104 776 262 283 388 O31463 1.62e-60 Homocysteine S-methyltransferase YbgG (EC 2.1.1.10) (S-methylmethionine:homocysteine methyltransferase) Bacillus subtilis (strain 168) methionine biosynthetic process [GO:0009086]; methylation [GO:0032259]; S-methylmethionine cycle [GO:0033528] GO:0008270; GO:0008898; GO:0009086; GO:0032259; GO:0033528; GO:0061627 3003 XM_029335123.2 977 636 501 601 522 NA NA NA NA NA NA 3004 XM_029332296.2 127 53 43 82 83 Q9BYG0 1.21e-32 Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase (EC 2.4.1.206) (Lactotriaosylceramide synthase) (Lc(3)Cer synthase) (Lc3 synthase) (UDP-GlcNAc:beta-Gal beta-1,3-N-acetylglucosaminyltransferase 5) (BGnT-5) (Beta-1,3-Gn-T5) (Beta-1,3-N-acetylglucosaminyltransferase 5) (Beta3Gn-T5) Homo sapiens (Human) brain development [GO:0007420]; central nervous system development [GO:0007417]; glycolipid biosynthetic process [GO:0009247]; O-glycan processing [GO:0016266]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0007417; GO:0007420; GO:0008457; GO:0008499; GO:0009247; GO:0016266; GO:0016757; GO:0047256 3005 XM_029332702.2 0 93 30 227 88 NA NA NA NA NA NA 3006 XM_044319097.1 178 150 168 138 125 A2BGU9 6.19e-49 Serine hydrolase-like protein (EC 3.1.-.-) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0016787 3007 XM_029344675.2 658 4266 2050 5499 2627 Q5R6S2 5.17e-25 GTP-binding protein Di-Ras2 (Distinct subgroup of the Ras family member 2) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) signal transduction [GO:0007165] GO:0003924; GO:0005525; GO:0005886; GO:0007165 3008 XM_029355183.2 992 957 551 583 931 Q15256 2.04e-77 Receptor-type tyrosine-protein phosphatase R (R-PTP-R) (EC 3.1.3.48) (Ch-1PTPase) (NC-PTPCOM1) (Protein-tyrosine phosphatase PCPTP1) Homo sapiens (Human) ERBB2 signaling pathway [GO:0038128]; in utero embryonic development [GO:0001701]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; signal transduction [GO:0007165] GO:0001701; GO:0004725; GO:0005001; GO:0005615; GO:0005829; GO:0005886; GO:0006470; GO:0007165; GO:0010633; GO:0019901; GO:0030054; GO:0035335; GO:0038128; GO:0048471; GO:0070373 3009 XM_029326727.2 0 10 0 0 3 NA NA NA NA NA NA 3010 XM_029343819.2 2657 2613 1606 2868 2603 Q9HCE0 0 Ectopic P granules protein 5 homolog Homo sapiens (Human) autophagosome maturation [GO:0097352]; cellular response to dsDNA [GO:1990786]; endocytic recycling [GO:0032456]; endosome to lysosome transport [GO:0008333]; nucleotide transport [GO:0006862]; toll-like receptor 9 signaling pathway [GO:0034162] GO:0005737; GO:0005764; GO:0006862; GO:0008333; GO:0032456; GO:0034162; GO:0048471; GO:0097352; GO:1990786 3011 XM_029344696.2 1509 1928 1271 1390 1231 Q6DEL1 5.44e-85 Sodium-coupled neutral amino acid transporter 7 (Solute carrier family 38 member 7) Danio rerio (Zebrafish) (Brachydanio rerio) amino acid transmembrane transport [GO:0003333]; asparagine transport [GO:0006867]; glutamine transport [GO:0006868] GO:0003333; GO:0005290; GO:0005313; GO:0005765; GO:0006867; GO:0006868; GO:0015179; GO:0015180; GO:0015182; GO:0015183; GO:0015186; GO:0015190; GO:0015191; GO:0015194; GO:0030424; GO:0140901; GO:0140902 3012 XM_044325727.1 325 104 1208 1755 2468 O88572 7.09e-95 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 3013 XM_044325727.1 325 104 1208 1755 2468 O88572 4.14e-86 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 3014 XM_044325727.1 325 104 1208 1755 2468 O88572 3.91e-75 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 3015 XM_044325727.1 325 104 1208 1755 2468 O88572 1.92e-65 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 3016 XM_044325727.1 325 104 1208 1755 2468 O88572 8.32e-58 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 3017 XM_044325727.1 325 104 1208 1755 2468 O88572 1.29e-46 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 3018 XM_044325727.1 325 104 1208 1755 2468 O88572 1.3e-40 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 3019 XM_044325727.1 325 104 1208 1755 2468 O88572 5.24e-39 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 3020 XM_044325727.1 325 104 1208 1755 2468 O88572 9.93e-38 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 3021 XM_044325727.1 325 104 1208 1755 2468 O88572 1.1e-35 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 3022 XM_044325727.1 325 104 1208 1755 2468 O88572 6.63e-35 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 3023 XM_044325727.1 325 104 1208 1755 2468 O88572 1.46e-33 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 3024 XM_044325727.1 325 104 1208 1755 2468 O88572 4.92e-32 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 3025 XM_044325727.1 325 104 1208 1755 2468 O88572 6.84e-24 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 3026 XM_044325727.1 325 104 1208 1755 2468 O88572 3.57e-21 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 3027 XM_044325169.1 16 6 27 6 5 NA NA NA NA NA NA 3028 XM_044321119.1 344 754 278 493 532 NA NA NA NA NA NA 3029 XM_029352555.2 8906 15138 8380 7601 6962 O70251 7.76e-90 Elongation factor 1-beta (EF-1-beta) Mus musculus (Mouse) response to ethanol [GO:0045471]; translational elongation [GO:0006414] GO:0003746; GO:0005085; GO:0005737; GO:0005783; GO:0005829; GO:0005853; GO:0006414; GO:0045471 3030 XM_044310796.1 124 41 130 127 84 Q96AY4 3.48e-125 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3031 XM_044310796.1 124 41 130 127 84 Q96AY4 2.32e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3032 XM_044310796.1 124 41 130 127 84 Q96AY4 2.22e-68 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3033 XM_044309872.1 20 0 27 0 19 NA NA NA NA NA NA 3034 XR_006394339.1 0 7 4 0 0 NA NA NA NA NA NA 3035 XM_029332713.2 0 6 39 10 18 Q2KJ63 1.47e-63 Plasma kallikrein (EC 3.4.21.34) (Fletcher factor) (Kininogenin) (Plasma prekallikrein) [Cleaved into: Plasma kallikrein heavy chain; Plasma kallikrein light chain] Bos taurus (Bovine) blood coagulation [GO:0007596]; fibrinolysis [GO:0042730]; inflammatory response [GO:0006954]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919] GO:0004252; GO:0005615; GO:0006954; GO:0007596; GO:0031639; GO:0042730; GO:0042803; GO:0051919 3036 XR_003825541.2 0 6 0 0 7 NA NA NA NA NA NA 3037 XM_029332842.2 103 25 140 85 192 Q16281 2.71e-59 Cyclic nucleotide-gated cation channel alpha-3 (Cone photoreceptor cGMP-gated channel subunit alpha) (Cyclic nucleotide-gated channel alpha-3) (CNG channel alpha-3) (CNG-3) (CNG3) Homo sapiens (Human) cation transmembrane transport [GO:0098655]; cation transport [GO:0006812]; inorganic cation import across plasma membrane [GO:0098659]; response to cAMP [GO:0051591]; response to corticosteroid [GO:0031960]; response to magnesium ion [GO:0032026]; signal transduction [GO:0007165]; visual perception [GO:0007601] GO:0005222; GO:0005223; GO:0005737; GO:0005886; GO:0006812; GO:0007165; GO:0007601; GO:0008022; GO:0015276; GO:0017071; GO:0030425; GO:0030553; GO:0031960; GO:0032026; GO:0043194; GO:0043204; GO:0044877; GO:0051591; GO:0097386; GO:0098655; GO:0098659; GO:1902495 3038 XM_029332860.2 1059 698 547 565 676 B3DJT0 1.73e-149 Squamous cell carcinoma antigen recognized by T-cells 3 (SART-3) Danio rerio (Zebrafish) (Brachydanio rerio) exocrine pancreas development [GO:0031017]; lymphocyte differentiation [GO:0030098]; mRNA splicing, via spliceosome [GO:0000398]; nucleosome assembly [GO:0006334]; positive regulation of histone deubiquitination [GO:1903586]; spliceosomal complex assembly [GO:0000245]; spliceosomal snRNP assembly [GO:0000387]; thymus development [GO:0048538] GO:0000245; GO:0000387; GO:0000398; GO:0005634; GO:0005654; GO:0005737; GO:0006334; GO:0015030; GO:0016607; GO:0017070; GO:0030098; GO:0031017; GO:0042393; GO:0048538; GO:0061574; GO:1903586 3039 XM_029332860.2 1059 698 547 565 676 B3DJT0 1.84e-50 Squamous cell carcinoma antigen recognized by T-cells 3 (SART-3) Danio rerio (Zebrafish) (Brachydanio rerio) exocrine pancreas development [GO:0031017]; lymphocyte differentiation [GO:0030098]; mRNA splicing, via spliceosome [GO:0000398]; nucleosome assembly [GO:0006334]; positive regulation of histone deubiquitination [GO:1903586]; spliceosomal complex assembly [GO:0000245]; spliceosomal snRNP assembly [GO:0000387]; thymus development [GO:0048538] GO:0000245; GO:0000387; GO:0000398; GO:0005634; GO:0005654; GO:0005737; GO:0006334; GO:0015030; GO:0016607; GO:0017070; GO:0030098; GO:0031017; GO:0042393; GO:0048538; GO:0061574; GO:1903586 3040 XM_044308613.1 91 0 43 191 0 NA NA NA NA NA NA 3041 XM_044315333.1 25 45 59 93 171 NA NA NA NA NA NA 3042 XM_044311109.1 0 0 6 0 0 NA NA NA NA NA NA 3043 XM_044316709.1 584 1093 562 412 315 NA NA NA NA NA NA 3044 XM_029350179.2 857 0 938 775 371 Q92870 9.99e-58 Amyloid beta precursor protein binding family B member 2 (Amyloid-beta (A4) precursor protein-binding family B member 2) (Protein Fe65-like 1) Homo sapiens (Human) intracellular signal transduction [GO:0035556]; maintenance of lens transparency [GO:0036438]; negative regulation of cell cycle phase transition [GO:1901988]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; smooth muscle contraction [GO:0006939]; synapse organization [GO:0050808] GO:0000122; GO:0001540; GO:0005634; GO:0005737; GO:0005769; GO:0005783; GO:0005794; GO:0006355; GO:0006939; GO:0016020; GO:0030027; GO:0030426; GO:0035556; GO:0036438; GO:0045202; GO:0045944; GO:0050808; GO:1901988 3045 XM_044315042.1 21 26 15 22 60 Q9CYL5 7.18e-23 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Mus musculus (Mouse) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070374 3046 XM_044319281.1 349 5 9 72 147 Q8TEP8 1.01e-152 Centrosomal protein of 192 kDa (Cep192) (Cep192/SPD-2) Homo sapiens (Human) centriole replication [GO:0007099]; centrosome-templated microtubule nucleation [GO:0090222]; mitotic spindle assembly [GO:0090307]; protein localization to centrosome [GO:0071539]; response to bacterium [GO:0009617] GO:0000242; GO:0005737; GO:0005813; GO:0005814; GO:0005829; GO:0007099; GO:0009617; GO:0019901; GO:0019902; GO:0071539; GO:0090222; GO:0090307; GO:0120098; GO:0120099 3047 XM_029350243.2 8 1 6 1 22 Q9DC58 4.95e-32 DNA damage-regulated autophagy modulator protein 1 (Damage-regulated autophagy modulator) Mus musculus (Mouse) apoptotic process [GO:0006915]; autophagy [GO:0006914]; regulation of autophagy [GO:0010506] GO:0005737; GO:0005764; GO:0005765; GO:0006914; GO:0006915; GO:0010506 3048 XM_044329142.1 248 470 52 242 69 Q62867 7.1e-72 Gamma-glutamyl hydrolase (EC 3.4.19.9) (Conjugase) (GH) (Gamma-Glu-X carboxypeptidase) Rattus norvegicus (Rat) poly-gamma-glutamate metabolic process [GO:0070500]; response to ethanol [GO:0045471]; response to insulin [GO:0032868]; response to xenobiotic stimulus [GO:0009410]; response to zinc ion [GO:0010043]; tetrahydrofolylpolyglutamate metabolic process [GO:0046900] GO:0005615; GO:0005764; GO:0005773; GO:0005829; GO:0009410; GO:0010043; GO:0032868; GO:0034722; GO:0042470; GO:0045471; GO:0046900; GO:0070500 3049 XM_044318647.1 1388 696 1014 1905 1996 O70258 7.61e-37 Epsilon-sarcoglycan (Epsilon-SG) Mus musculus (Mouse) NA GO:0005794; GO:0005856; GO:0005886; GO:0016010; GO:0016012; GO:0032590; GO:0042383 3050 XM_029347969.2 2466 1369 875 2150 2097 NA NA NA NA NA NA 3051 XM_044307966.1 7 0 7 0 0 NA NA NA NA NA NA 3052 XM_044308346.1 7356 2457 680 3723 3854 Q5R4N8 4.78e-170 Alpha-2-macroglobulin (Alpha-2-M) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) negative regulation of peptidase activity [GO:0010466] GO:0004867; GO:0005615; GO:0010466 3053 XM_044308346.1 7356 2457 680 3723 3854 Q5R4N8 4.78e-170 Alpha-2-macroglobulin (Alpha-2-M) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) negative regulation of peptidase activity [GO:0010466] GO:0004867; GO:0005615; GO:0010466 3054 XM_029326348.2 6 2 3 6 3 NA NA NA NA NA NA 3055 XR_006393409.1 0 0 3 2 204 NA NA NA NA NA NA 3056 XR_006394024.1 14 21 11 24 12 NA NA NA NA NA NA 3057 XM_044324756.1 5 22 12 23 15 NA NA NA NA NA NA 3058 XM_029356750.2 2488 2198 1834 2681 2744 O88831 5.46e-128 Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) (CaMKK 2) (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-KK beta) (CaM-kinase kinase beta) (CaMKK beta) Rattus norvegicus (Rat) activation of protein kinase activity [GO:0032147]; CAMKK-AMPK signaling cascade [GO:0061762]; positive regulation of protein phosphorylation [GO:0001934]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165] GO:0001934; GO:0004672; GO:0004674; GO:0004683; GO:0005509; GO:0005516; GO:0005524; GO:0005654; GO:0005737; GO:0006468; GO:0007165; GO:0030295; GO:0032147; GO:0043005; GO:0046777; GO:0061762; GO:0106310 3059 XM_044321330.1 0 0 0 121 0 P46023 1.15e-40 G-protein coupled receptor GRL101 Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004930; GO:0005886 3060 XM_044322471.1 12 0 0 12 18 Q80XJ3 2.73e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 3061 XM_044322471.1 12 0 0 12 18 Q80XJ3 6.95e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 3062 XM_044322471.1 12 0 0 12 18 Q80XJ3 1.69e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 3063 XR_003822986.1 3 0 4 0 20 NA NA NA NA NA NA 3064 XM_044326245.1 65 105 96 46 113 NA NA NA NA NA NA 3065 XM_044328406.1 12 1 8 0 5 NA NA NA NA NA NA 3066 XM_044318812.1 187 0 13 0 54 NA NA NA NA NA NA 3067 XR_006395743.1 286 27 0 0 0 A0A1J6KGJ9 1.19e-53 Jasmonoyl--L-amino acid synthetase JAR4 (EC 6.3.2.52) (Jasmonate-amino acid synthetase JAR4) (Jasmonic acid-amido synthetase JAR4) (Protein JASMONATE RESISTANT 4) Nicotiana attenuata (Coyote tobacco) defense response [GO:0006952] GO:0005524; GO:0006952; GO:0102053; GO:0102057; GO:0102058 3068 XM_029350961.2 339 313 46 81 50 P35604 5.73e-87 Coatomer subunit zeta-1 (Zeta-1-coat protein) (Zeta-1 COP) Bos taurus (Bovine) intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; toxin transport [GO:1901998] GO:0000139; GO:0006886; GO:0006890; GO:0006891; GO:0030126; GO:1901998 3069 XM_044308476.1 50712 63351 40920 40256 16142 Q78P75 8.52e-60 Dynein light chain 2, cytoplasmic (Dynein light chain LC8-type 2) Rattus norvegicus (Rat) microtubule-based process [GO:0007017] GO:0005737; GO:0005813; GO:0005856; GO:0005868; GO:0005874; GO:0007017; GO:0014069; GO:0031475; GO:0042802; GO:0044877; GO:0045505; GO:0097110; GO:0097731; GO:0098794; GO:0098978 3070 XM_044308476.1 50712 63351 40920 40256 16142 Q78P75 2.52e-30 Dynein light chain 2, cytoplasmic (Dynein light chain LC8-type 2) Rattus norvegicus (Rat) microtubule-based process [GO:0007017] GO:0005737; GO:0005813; GO:0005856; GO:0005868; GO:0005874; GO:0007017; GO:0014069; GO:0031475; GO:0042802; GO:0044877; GO:0045505; GO:0097110; GO:0097731; GO:0098794; GO:0098978 3071 XM_044319275.1 1 13 0 0 0 NA NA NA NA NA NA 3072 XM_044320928.1 30 0 268 63 185 Q9VBW3 1.97e-58 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 3073 XM_029338442.2 754 663 335 598 328 A4FUP9 8.88e-97 Glycosyltransferase 1 domain-containing protein 1 (EC 2.4.-.-) Mus musculus (Mouse) NA GO:0005576; GO:0005829; GO:0016757 3074 XR_006395284.1 8 0 1 0 0 NA NA NA NA NA NA 3075 XM_029331250.2 552 280 382 613 1025 P48442 1.61e-119 Extracellular calcium-sensing receptor (CaSR) (Parathyroid cell calcium-sensing receptor) (PCaR1) (RaKCaR) Rattus norvegicus (Rat) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; apoptotic process [GO:0006915]; bile acid secretion [GO:0032782]; branching morphogenesis of an epithelial tube [GO:0048754]; calcium ion import [GO:0070509]; cellular calcium ion homeostasis [GO:0006874]; cellular response to glucose stimulus [GO:0071333]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hypoxia [GO:0071456]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to peptide [GO:1901653]; cellular response to vitamin D [GO:0071305]; chloride transmembrane transport [GO:1902476]; detection of calcium ion [GO:0005513]; fat pad development [GO:0060613]; G protein-coupled receptor signaling pathway [GO:0007186]; JNK cascade [GO:0007254]; ossification [GO:0001503]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of ATP-dependent activity [GO:0032781]; positive regulation of calcium ion import [GO:0090280]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin secretion [GO:0032024]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of vasoconstriction [GO:0045907]; regulation of calcium ion transport [GO:0051924]; response to calcium ion [GO:0051592]; response to fibroblast growth factor [GO:0071774]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to organic cyclic compound [GO:0014070]; vasodilation [GO:0042311] GO:0001503; GO:0002931; GO:0004930; GO:0005178; GO:0005509; GO:0005513; GO:0005634; GO:0005737; GO:0005886; GO:0006874; GO:0006915; GO:0007186; GO:0007193; GO:0007200; GO:0007254; GO:0008284; GO:0009986; GO:0010038; GO:0010628; GO:0014070; GO:0016020; GO:0016323; GO:0016324; GO:0016597; GO:0019901; GO:0030424; GO:0032024; GO:0032781; GO:0032782; GO:0035729; GO:0042311; GO:0042803; GO:0043005; GO:0043025; GO:0043679; GO:0044325; GO:0045907; GO:0048754; GO:0050927; GO:0051592; GO:0051924; GO:0060613; GO:0070374; GO:0070509; GO:0071305; GO:0071333; GO:0071404; GO:0071456; GO:0071774; GO:0090280; GO:1901653; GO:1902476 3076 XM_029344249.2 1781 1499 1731 2526 2948 O94844 1.37e-120 Rho-related BTB domain-containing protein 1 Homo sapiens (Human) actin filament organization [GO:0007015]; cortical cytoskeleton organization [GO:0030865]; engulfment of apoptotic cell [GO:0043652]; establishment or maintenance of cell polarity [GO:0007163]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; small GTPase mediated signal transduction [GO:0007264] GO:0003924; GO:0005525; GO:0005856; GO:0005886; GO:0005938; GO:0007015; GO:0007163; GO:0007264; GO:0008360; GO:0010008; GO:0019901; GO:0030865; GO:0031410; GO:0032956; GO:0042995; GO:0043652 3077 XR_006397740.1 623 330 257 289 608 NA NA NA NA NA NA 3078 XM_044321662.1 174 107 4 18 32 E9Q5R7 7.91e-56 NACHT, LRR and PYD domains-containing protein 12 (Monarch-1) (PYRIN-containing APAF1-like protein 7) (PYPAF7) Mus musculus (Mouse) cellular response to cytokine stimulus [GO:0071345]; dendritic cell migration [GO:0036336]; ERK1 and ERK2 cascade [GO:0070371]; negative regulation of cytokine production [GO:0001818]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of signal transduction [GO:0009968]; negative regulation of Toll signaling pathway [GO:0045751]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of inflammatory response [GO:0050727] GO:0001818; GO:0005524; GO:0005737; GO:0009968; GO:0031953; GO:0032088; GO:0032692; GO:0032715; GO:0036336; GO:0038061; GO:0043122; GO:0043124; GO:0043281; GO:0045345; GO:0045751; GO:0050727; GO:0050728; GO:0070371; GO:0070373; GO:0071345; GO:1901223; GO:1901224 3079 XM_029341346.2 9 0 0 0 8 NA NA NA NA NA NA 3080 XM_029358343.2 9 0 0 0 0 Q9PU85 3.73e-43 Serine/threonine-protein kinase pim-3 (EC 2.7.11.1) (qpim) Coturnix japonica (Japanese quail) (Coturnix coturnix japonica) negative regulation of apoptotic process [GO:0043066]; protein phosphorylation [GO:0006468] GO:0004674; GO:0005524; GO:0005737; GO:0006468; GO:0043066; GO:0106310 3081 XR_006398153.1 412 627 264 285 253 NA NA NA NA NA NA 3082 XM_029344742.2 14 0 0 107 0 NA NA NA NA NA NA 3083 XM_044318185.1 736 530 235 328 294 Q1T7B8 3.5e-22 Centromere protein O (CENP-O) Gallus gallus (Chicken) centromere complex assembly [GO:0034508] GO:0005634; GO:0031511; GO:0034508 3084 XM_044314765.1 17 49 16 106 5 NA NA NA NA NA NA 3085 XM_029353126.2 77 101 88 67 26 Q9C056 2.93e-38 Homeobox protein Nkx-6.2 (Homeobox protein NK-6 homolog B) Homo sapiens (Human) cell differentiation [GO:0030154]; central nervous system myelination [GO:0022010]; negative regulation of cell fate commitment [GO:0010454]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of oligodendrocyte differentiation [GO:0048715]; neuromuscular process controlling balance [GO:0050885]; neuron fate commitment [GO:0048663]; pancreatic A cell differentiation [GO:0003310]; positive regulation of cell fate commitment [GO:0010455]; positive regulation of oligodendrocyte differentiation [GO:0048714]; regulation of DNA-templated transcription [GO:0006355]; regulation of myelination [GO:0031641]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000785; GO:0000978; GO:0000981; GO:0001227; GO:0003310; GO:0003677; GO:0003700; GO:0005634; GO:0006355; GO:0006357; GO:0010454; GO:0010455; GO:0022010; GO:0030154; GO:0031641; GO:0045892; GO:0048663; GO:0048714; GO:0048715; GO:0050885; GO:1990837 3086 XM_044325448.1 288 0 0 26 0 Q867C9 0 ATP-dependent 6-phosphofructokinase, muscle type (ATP-PFK) (PFK-M) (EC 2.7.1.11) (6-phosphofructokinase type A) (Phosphofructo-1-kinase isozyme A) (PFK-A) (Phosphohexokinase) Equus caballus (Horse) canonical glycolysis [GO:0061621]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose 6-phosphate metabolic process [GO:0006002] GO:0003872; GO:0005524; GO:0005945; GO:0006002; GO:0016020; GO:0016208; GO:0030388; GO:0042802; GO:0046872; GO:0048029; GO:0061621; GO:0070095 3087 XM_044325793.1 0 0 0 0 6 NA NA NA NA NA NA 3088 XM_029349957.2 192 66 144 170 168 NA NA NA NA NA NA 3089 XM_029325640.2 465 159 210 366 267 Q6DFR1 5.72e-60 Solute carrier family 22 member 15 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) ion transport [GO:0006811] GO:0006811; GO:0016020; GO:0022857 3090 XM_029335073.2 405 97 210 502 293 A1KZ92 4.16e-27 Probable oxidoreductase PXDNL (EC 1.-.-.-) (Cardiac peroxidase) (Inactive peroxidasin-like protein) (Polysomal ribonuclease 1) (PRM1) (Vascular peroxidase 2) Homo sapiens (Human) hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979] GO:0004519; GO:0004601; GO:0005615; GO:0005783; GO:0005886; GO:0006979; GO:0020037; GO:0042744; GO:0046872; GO:0140825 3091 XM_029335073.2 405 97 210 502 293 A1KZ92 3.57e-23 Probable oxidoreductase PXDNL (EC 1.-.-.-) (Cardiac peroxidase) (Inactive peroxidasin-like protein) (Polysomal ribonuclease 1) (PRM1) (Vascular peroxidase 2) Homo sapiens (Human) hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979] GO:0004519; GO:0004601; GO:0005615; GO:0005783; GO:0005886; GO:0006979; GO:0020037; GO:0042744; GO:0046872; GO:0140825 3092 XM_044326826.1 1 1 0 10 4 NA NA NA NA NA NA 3093 XM_029343137.2 85 143 125 119 39 Q3MIE0 6.33e-112 Enoyl-CoA hydratase domain-containing protein 3, mitochondrial Rattus norvegicus (Rat) fatty acid metabolic process [GO:0006631]; positive regulation of cellular response to insulin stimulus [GO:1900078] GO:0004300; GO:0005739; GO:0006631; GO:0016836; GO:1900078 3094 XM_029356458.2 125 72 72 153 155 Q07G10 5.66e-172 Alkylated DNA repair protein alkB homolog 8 (Probable alpha-ketoglutarate-dependent dioxygenase ABH8) (S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8) (tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8) (EC 2.1.1.-, EC 2.1.1.229) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) tRNA methylation [GO:0030488]; tRNA wobble uridine modification [GO:0002098] GO:0000049; GO:0002098; GO:0005506; GO:0005634; GO:0005829; GO:0008270; GO:0016300; GO:0030488; GO:0106335 3095 XM_029357239.2 631 579 480 694 544 Q64323 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit A (EC 2.4.1.198) (GlcNAc-PI synthesis protein) (Phosphatidylinositol-glycan biosynthesis class A protein) (PIG-A) Mus musculus (Mouse) cellular response to leukemia inhibitory factor [GO:1990830]; GPI anchor biosynthetic process [GO:0006506] GO:0000506; GO:0005789; GO:0006506; GO:0017176; GO:1990830 3096 XR_003827026.2 2672 2890 1285 1938 1760 NA NA NA NA NA NA 3097 XR_006396353.1 0 1 2 0 6 NA NA NA NA NA NA 3098 XM_044317361.1 714 1235 1 1213 2 Q9ULV0 0 Unconventional myosin-Vb Homo sapiens (Human) actin filament organization [GO:0007015]; endosomal transport [GO:0016197]; protein transport [GO:0015031]; renal water homeostasis [GO:0003091]; vesicle transport along actin filament [GO:0030050]; vesicle-mediated transport [GO:0016192] GO:0000146; GO:0003091; GO:0005516; GO:0005524; GO:0005737; GO:0007015; GO:0015031; GO:0015629; GO:0016192; GO:0016197; GO:0016459; GO:0030050; GO:0030659; GO:0031267; GO:0031982; GO:0032991; GO:0045179; GO:0051015; GO:0070062 3099 XM_044317361.1 714 1235 1 1213 2 Q9ULV0 1.06e-112 Unconventional myosin-Vb Homo sapiens (Human) actin filament organization [GO:0007015]; endosomal transport [GO:0016197]; protein transport [GO:0015031]; renal water homeostasis [GO:0003091]; vesicle transport along actin filament [GO:0030050]; vesicle-mediated transport [GO:0016192] GO:0000146; GO:0003091; GO:0005516; GO:0005524; GO:0005737; GO:0007015; GO:0015031; GO:0015629; GO:0016192; GO:0016197; GO:0016459; GO:0030050; GO:0030659; GO:0031267; GO:0031982; GO:0032991; GO:0045179; GO:0051015; GO:0070062 3100 XM_029343643.2 8 5 17 42 39 NA NA NA NA NA NA 3101 XM_044314523.1 13 5 7 150 62 NA NA NA NA NA NA 3102 XM_044321003.1 82 0 65 0 0 A2ASQ1 5.54e-22 Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment (C90); Agrin C-terminal 22 kDa fragment (C22)] Mus musculus (Mouse) animal organ morphogenesis [GO:0009887]; cell differentiation [GO:0030154]; chemical synaptic transmission [GO:0007268]; motor neuron apoptotic process [GO:0097049]; negative regulation of P-type sodium:potassium-exchanging transporter activity [GO:1903407]; negative regulation of sodium ion export across plasma membrane [GO:1903277]; neuromuscular junction development [GO:0007528]; neurotransmitter receptor metabolic process [GO:0045213]; plasma membrane organization [GO:0007009]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of motor neuron apoptotic process [GO:2000673]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein binding [GO:0032092]; positive regulation of protein geranylgeranylation [GO:2000541]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of synaptic assembly at neuromuscular junction [GO:0045887]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor clustering [GO:0043113]; regulation of axon guidance [GO:1902667]; regulation of cardiac muscle cell membrane potential [GO:0086036]; regulation of cardiac muscle contraction [GO:0055117]; regulation of GTPase activity [GO:0043087]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of protein phosphorylation [GO:0001932]; regulation of synapse organization [GO:0050807]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse assembly [GO:0007416]; tissue development [GO:0009888] GO:0001932; GO:0001934; GO:0002162; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005796; GO:0007009; GO:0007268; GO:0007416; GO:0007528; GO:0009887; GO:0009888; GO:0009986; GO:0030154; GO:0030548; GO:0032092; GO:0033691; GO:0035374; GO:0036122; GO:0042030; GO:0042383; GO:0043083; GO:0043087; GO:0043113; GO:0043395; GO:0043547; GO:0044295; GO:0044325; GO:0045202; GO:0045213; GO:0045887; GO:0045944; GO:0050431; GO:0050731; GO:0050807; GO:0051491; GO:0055117; GO:0061098; GO:0062023; GO:0070507; GO:0071340; GO:0086036; GO:0097049; GO:0098978; GO:1902667; GO:1903277; GO:1903407; GO:2000541; GO:2000673 3103 XM_044322954.1 61 180 87 97 117 Q86WI3 2.4e-26 Protein NLRC5 (Caterpiller protein 16.1) (CLR16.1) (Nucleotide-binding oligomerization domain protein 27) (Nucleotide-binding oligomerization domain protein 4) Homo sapiens (Human) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of type II interferon-mediated signaling pathway [GO:0060335]; regulation of kinase activity [GO:0043549]; response to bacterium [GO:0009617] GO:0000978; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0009617; GO:0032088; GO:0035556; GO:0043549; GO:0045087; GO:0045345; GO:0045944; GO:0051607; GO:0060335; GO:0060339; GO:0060340 3104 XM_029323602.2 2268 2241 1557 2576 1835 Q6PCF7 1.57e-127 Ubiquitin-conjugating enzyme E2 Z (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme Z) (Ubiquitin carrier protein Z) (Ubiquitin-protein ligase Z) Xenopus laevis (African clawed frog) apoptotic process [GO:0006915] GO:0005524; GO:0005634; GO:0005737; GO:0006915; GO:0061631 3105 XR_003828593.2 43 7 1 1 6 NA NA NA NA NA NA 3106 XM_029325936.2 280 151 26 74 378 O60825 4.41e-163 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (6PF-2-K/Fru-2,6-P2ase 2) (PFK/FBPase 2) (6PF-2-K/Fru-2,6-P2ase heart-type isozyme) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)] Homo sapiens (Human) fructose 2,6-bisphosphate metabolic process [GO:0006003]; fructose metabolic process [GO:0006000]; glucose catabolic process [GO:0006007]; glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; positive regulation of glucokinase activity [GO:0033133]; positive regulation of insulin secretion [GO:0032024]; response to glucose [GO:0009749] GO:0003873; GO:0004331; GO:0005524; GO:0005654; GO:0005829; GO:0006000; GO:0006003; GO:0006007; GO:0006089; GO:0006096; GO:0009749; GO:0019901; GO:0032024; GO:0033133 3107 XM_044307631.1 21 1869 319 248 902 NA NA NA NA NA NA 3108 XM_029352665.1 8 7 12 26 61 NA NA NA NA NA NA 3109 XM_029327393.2 4147 3392 1684 3128 2864 Q5ZMP6 0 AP-2 complex subunit mu (AP-2 mu chain) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (HA2 50 kDa subunit) (Mu2-adaptin) (Plasma membrane adaptor AP-2 50 kDa protein) Gallus gallus (Chicken) clathrin-dependent endocytosis [GO:0072583]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192] GO:0006886; GO:0006897; GO:0008289; GO:0016192; GO:0030122; GO:0031410; GO:0035615; GO:0072583 3110 XM_029328765.2 560 275 233 295 471 NA NA NA NA NA NA 3111 XM_029347981.2 1750 1526 1427 1914 2135 Q03601 3.38e-40 RING finger protein nhl-1 Caenorhabditis elegans negative regulation of translation [GO:0017148]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567] GO:0000209; GO:0004842; GO:0016567; GO:0017148; GO:0030371; GO:0043161; GO:0046872; GO:0061630 3112 XM_029339200.2 160 218 133 135 122 NA NA NA NA NA NA 3113 XM_029328869.2 0 188 359 0 505 Q8NI36 0 WD repeat-containing protein 36 (T-cell activation WD repeat-containing protein) (TA-WDRP) Homo sapiens (Human) response to stimulus [GO:0050896]; rRNA processing [GO:0006364]; visual perception [GO:0007601] GO:0003723; GO:0005654; GO:0005730; GO:0006364; GO:0007601; GO:0032040; GO:0034388; GO:0050896 3114 XM_044312788.1 3 0 0 0 6 NA NA NA NA NA NA 3115 XM_044316468.1 231 32 2 322 102 NA NA NA NA NA NA 3116 XM_044314763.1 37 7 72 86 83 P0CT40 6.22e-76 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 3117 XR_003827374.2 24725 32320 18558 28477 8440 NA NA NA NA NA NA 3118 XM_044319453.1 2 4 5 17 12 NA NA NA NA NA NA 3119 XM_044311520.1 3 2 1 6 1 NA NA NA NA NA NA 3120 XR_006394226.1 60 25 0 0 60 NA NA NA NA NA NA 3121 XM_044311619.1 43 32 38 7 5 NA NA NA NA NA NA 3122 XM_029328546.2 134 94 68 105 172 Q3V129 0 Serine/threonine-protein kinase ULK4 (EC 2.7.11.1) (Unc-51-like kinase 4) Mus musculus (Mouse) adult behavior [GO:0030534]; axoneme assembly [GO:0035082]; brain development [GO:0007420]; central nervous system myelination [GO:0022010]; cerebrospinal fluid circulation [GO:0090660]; ciliary basal body organization [GO:0032053]; corpus callosum development [GO:0022038]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; GABAergic neuron differentiation [GO:0097154]; gene expression [GO:0010467]; microtubule cytoskeleton organization [GO:0000226]; motile cilium assembly [GO:0044458]; neurogenesis [GO:0022008]; neuroinflammatory response [GO:0150076]; neuronal stem cell division [GO:0036445]; protein phosphorylation [GO:0006468]; regulation of JNK cascade [GO:0046328]; regulation of MAPK cascade [GO:0043408]; regulation of neuron migration [GO:2001222]; regulation of neuron projection development [GO:0010975]; regulation of p38MAPK cascade [GO:1900744]; regulation of protein kinase C signaling [GO:0090036]; social behavior [GO:0035176]; ventricular system development [GO:0021591] GO:0000226; GO:0003351; GO:0004674; GO:0005524; GO:0005576; GO:0006468; GO:0007420; GO:0010467; GO:0010975; GO:0021591; GO:0022008; GO:0022010; GO:0022038; GO:0030534; GO:0032053; GO:0035082; GO:0035176; GO:0036445; GO:0043408; GO:0044458; GO:0046328; GO:0051649; GO:0090036; GO:0090660; GO:0097154; GO:0106310; GO:0150076; GO:1900744; GO:2001222 3123 XM_029344139.2 377 237 290 352 174 Q6NS52 0 Diacylglycerol kinase beta (DAG kinase beta) (EC 2.7.1.107) (Diglyceride kinase beta) (DGK-beta) Mus musculus (Mouse) diacylglycerol metabolic process [GO:0046339]; glycerolipid metabolic process [GO:0046486]; intracellular signal transduction [GO:0035556]; lipid phosphorylation [GO:0046834]; modulation of chemical synaptic transmission [GO:0050804]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidic acid metabolic process [GO:0046473]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; regulation of postsynapse organization [GO:0099175]; response to bacterium [GO:0009617] GO:0004143; GO:0005509; GO:0005524; GO:0005829; GO:0005886; GO:0006654; GO:0007205; GO:0008289; GO:0009617; GO:0016020; GO:0035556; GO:0046339; GO:0046473; GO:0046486; GO:0046834; GO:0050804; GO:0098685; GO:0098978; GO:0099147; GO:0099175 3124 XM_044310470.1 264 240 90 118 300 NA NA NA NA NA NA 3125 XM_029348121.2 577 607 375 594 718 O76075 4.53e-66 DNA fragmentation factor subunit beta (EC 3.-.-.-) (Caspase-activated deoxyribonuclease) (CAD) (Caspase-activated DNase) (Caspase-activated nuclease) (CPAN) (DNA fragmentation factor 40 kDa subunit) (DFF-40) Homo sapiens (Human) apoptotic chromosome condensation [GO:0030263]; apoptotic DNA fragmentation [GO:0006309]; DNA catabolic process [GO:0006308]; negative regulation of apoptotic DNA fragmentation [GO:1902511] GO:0000785; GO:0003677; GO:0004520; GO:0004536; GO:0005634; GO:0005654; GO:0005730; GO:0005829; GO:0006308; GO:0006309; GO:0019899; GO:0019904; GO:0030263; GO:0032991; GO:0042802; GO:0097718; GO:1902511 3126 XM_044313222.1 22 5 9 10 10 NA NA NA NA NA NA 3127 XM_029355401.2 4 2 5 7 17 NA NA NA NA NA NA 3128 XM_044316569.1 15 47 49 37 88 NA NA NA NA NA NA 3129 XM_029330425.2 0 18 0 9 0 O43603 8.08e-29 Galanin receptor type 2 (GAL2-R) (GALR-2) Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell surface receptor signaling pathway [GO:0007166]; feeding behavior [GO:0007631]; galanin-activated signaling pathway [GO:0090663]; inositol phosphate metabolic process [GO:0043647]; learning or memory [GO:0007611]; muscle contraction [GO:0006936]; negative regulation of adenylate cyclase activity [GO:0007194]; neuron projection development [GO:0031175]; neuropeptide signaling pathway [GO:0007218]; phosphatidylinositol metabolic process [GO:0046488]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of large conductance calcium-activated potassium channel activity [GO:1902608]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0004966; GO:0005886; GO:0005929; GO:0006936; GO:0007166; GO:0007188; GO:0007189; GO:0007194; GO:0007200; GO:0007204; GO:0007218; GO:0007611; GO:0007631; GO:0008528; GO:0016020; GO:0017046; GO:0031175; GO:0042923; GO:0043647; GO:0045944; GO:0046488; GO:0090663; GO:1902608 3130 XR_006396807.1 190 63 0 0 184 Q8CJG0 0 Protein argonaute-2 (Argonaute2) (mAgo2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (Piwi/argonaute family protein meIF2C2) (Protein slicer) Mus musculus (Mouse) cell differentiation [GO:0030154]; miRNA metabolic process [GO:0010586]; miRNA processing [GO:0035196]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; miRNA-mediated gene silencing by mRNA destabilization [GO:0035279]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; negative regulation of translational initiation [GO:0045947]; positive regulation of angiogenesis [GO:0045766]; positive regulation of gene expression [GO:0010628]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of trophoblast cell migration [GO:1901165]; post-embryonic development [GO:0009791]; pre-miRNA processing [GO:0031054]; RISC complex assembly [GO:0070922]; RNA secondary structure unwinding [GO:0010501]; RNA-mediated gene silencing [GO:0031047]; siRNA processing [GO:0030422]; siRNA-mediated gene silencing by mRNA destabilization [GO:0090625] GO:0000340; GO:0000932; GO:0000993; GO:0001046; GO:0003723; GO:0003725; GO:0003727; GO:0003729; GO:0004521; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0005844; GO:0005845; GO:0008022; GO:0009791; GO:0010501; GO:0010586; GO:0010628; GO:0016442; GO:0030154; GO:0030422; GO:0030425; GO:0031047; GO:0031054; GO:0035196; GO:0035197; GO:0035198; GO:0035278; GO:0035279; GO:0036464; GO:0042985; GO:0045766; GO:0045944; GO:0045947; GO:0046872; GO:0060213; GO:0070062; GO:0070551; GO:0070578; GO:0070922; GO:0090624; GO:0090625; GO:0098808; GO:1900153; GO:1901165; GO:1990904 3131 XM_044311682.1 67 184 214 6 78 Q7RTR2 1.74e-32 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 3132 XM_029344995.2 132 117 78 134 69 Q9EQD2 2e-23 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 3133 XM_044311516.1 0 0 0 10 33 NA NA NA NA NA NA 3134 XM_044324056.1 491 553 310 559 851 Q14155 1.98e-126 Rho guanine nucleotide exchange factor 7 (Beta-Pix) (COOL-1) (PAK-interacting exchange factor beta) (p85) Homo sapiens (Human) ephrin receptor signaling pathway [GO:0048013]; focal adhesion assembly [GO:0048041]; Golgi organization [GO:0007030]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; negative regulation of microtubule nucleation [GO:1905833]; nervous system development [GO:0007399]; positive regulation of apoptotic process [GO:0043065]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of GTPase activity [GO:0043547]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of GTP binding [GO:1904424]; signal transduction [GO:0007165] GO:0001726; GO:0005085; GO:0005737; GO:0005813; GO:0005829; GO:0005925; GO:0005938; GO:0007030; GO:0007165; GO:0007399; GO:0010763; GO:0019901; GO:0030027; GO:0030032; GO:0032991; GO:0035556; GO:0043005; GO:0043015; GO:0043025; GO:0043065; GO:0043547; GO:0048013; GO:0048041; GO:0097431; GO:0098794; GO:1900026; GO:1904424; GO:1905833; GO:2000394 3135 XM_029334491.2 42 0 0 0 0 NA NA NA NA NA NA 3136 XM_044316606.1 1940 1812 1012 1848 1233 Q3KR37 1.24e-31 Protein Aster-B (GRAM domain-containing protein 1B) Homo sapiens (Human) cellular response to cholesterol [GO:0071397]; cholesterol homeostasis [GO:0042632]; intracellular sterol transport [GO:0032366] GO:0001786; GO:0005789; GO:0005886; GO:0015485; GO:0016020; GO:0032366; GO:0032934; GO:0042632; GO:0070300; GO:0071397; GO:0120015; GO:0120020; GO:0140268 3137 XM_029330048.2 385 114 258 639 202 Q504N0 9.19e-107 Carboxypeptidase A2 (EC 3.4.17.15) Mus musculus (Mouse) proteolysis [GO:0006508] GO:0004180; GO:0004181; GO:0005576; GO:0005615; GO:0006508; GO:0008270 3138 XM_044319095.1 3 2 0 18 21 NA NA NA NA NA NA 3139 XM_044324770.1 12 0 0 10 54 NA NA NA NA NA NA 3140 XM_029345366.2 1129 466 593 771 647 Q96GD3 2.36e-72 Polycomb protein SCMH1 (Sex comb on midleg homolog 1) Homo sapiens (Human) heterochromatin formation [GO:0031507]; negative regulation of DNA-templated transcription [GO:0045892] GO:0003682; GO:0005634; GO:0005654; GO:0031507; GO:0042393; GO:0045892 3141 XM_029344029.2 229 163 156 264 285 P16390 5.42e-121 Potassium voltage-gated channel subfamily A member 3 (MK3) (Voltage-gated potassium channel subunit Kv1.3) Mus musculus (Mouse) corpus callosum development [GO:0022038]; optic nerve development [GO:0021554]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005251; GO:0005886; GO:0008076; GO:0015271; GO:0016020; GO:0021554; GO:0022038; GO:0030424; GO:0034765; GO:0042734; GO:0044305; GO:0045121; GO:0045211; GO:0051260; GO:0071805; GO:0098978 3142 XM_029338556.2 0 0 0 31 0 NA NA NA NA NA NA 3143 XM_029355766.2 37 49 39 131 26 R1CW23 2.55e-104 Dimethylsulfonioproprionate lyase 7 (DMSP lyase 7) (EC 4.4.1.3) (Dimethylpropiothetin dethiomethylase 7) Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi) NA GO:0047869 3144 XM_044315055.1 836 515 573 534 1034 A2AAY5 4.35e-108 SH3 and PX domain-containing protein 2B (Factor for adipocyte differentiation 49) (Tyrosine kinase substrate with four SH3 domains) Mus musculus (Mouse) adipose tissue development [GO:0060612]; bone development [GO:0060348]; cranial skeletal system development [GO:1904888]; extracellular matrix disassembly [GO:0022617]; eye development [GO:0001654]; heart development [GO:0007507]; osteoblast fate commitment [GO:0002051]; podosome assembly [GO:0071800]; positive regulation of adipose tissue development [GO:1904179]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of gene expression [GO:0010628]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of stress fiber assembly [GO:0051496]; protein localization to membrane [GO:0072657]; regulation of brood size [GO:0060378]; skeletal system development [GO:0001501]; skeletal system morphogenesis [GO:0048705]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801] GO:0001501; GO:0001654; GO:0002051; GO:0002102; GO:0005737; GO:0006801; GO:0007507; GO:0010314; GO:0010628; GO:0016176; GO:0022617; GO:0032266; GO:0040018; GO:0042169; GO:0042554; GO:0042995; GO:0045600; GO:0048705; GO:0051496; GO:0060348; GO:0060378; GO:0060612; GO:0070161; GO:0070273; GO:0071800; GO:0072657; GO:0080025; GO:1904179; GO:1904888 3145 XM_029358509.2 87 111 39 36 63 NA NA NA NA NA NA 3146 XM_029347543.2 0 0 60 11 0 NA NA NA NA NA NA 3147 XM_044309060.1 166 112 140 358 144 Q3UQ28 2.03e-30 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 3148 XM_044309060.1 166 112 140 358 144 Q3UQ28 9.4e-28 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 3149 XM_044321620.1 888 240 461 569 393 Q7RTR2 2.95e-33 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 3150 XM_029339157.2 357 155 174 233 180 Q5RBN9 3.1e-124 Transcriptional adapter 2-beta Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) regulation of histone acetylation [GO:0035065]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0003713; GO:0005634; GO:0006357; GO:0008270; GO:0035065; GO:0070461 3151 XR_006397599.1 14 60 6 13 39 NA NA NA NA NA NA 3152 XM_044319475.1 30 0 3 0 0 NA NA NA NA NA NA 3153 XM_044326350.1 727 643 506 353 713 Q9NU19 1.8e-163 TBC1 domain family member 22B Homo sapiens (Human) activation of GTPase activity [GO:0090630] GO:0005096; GO:0071889; GO:0090630 3154 XM_044309068.1 34 590 26 259 313 NA NA NA NA NA NA 3155 XM_044326857.1 2 2 0 0 7 NA NA NA NA NA NA 3156 XR_006394079.1 169 25 25 2 135 NA NA NA NA NA NA 3157 XM_029350945.2 0 17 4 25 24 NA NA NA NA NA NA 3158 XM_029329101.2 0 64 240 0 201 Q96242 5.69e-29 Allene oxide synthase, chloroplastic (EC 4.2.1.92) (Cytochrome P450 74A) (Hydroperoxide dehydrase) Arabidopsis thaliana (Mouse-ear cress) defense response [GO:0006952]; defense response to fungus [GO:0050832]; epoxygenase P450 pathway [GO:0019373]; fatty acid biosynthetic process [GO:0006633]; jasmonic acid biosynthetic process [GO:0009695]; oxylipin biosynthetic process [GO:0031408]; oxylipin metabolic process [GO:0031407]; response to fungus [GO:0009620]; response to jasmonic acid [GO:0009753]; response to wounding [GO:0009611]; sterol metabolic process [GO:0016125] GO:0004497; GO:0005506; GO:0005739; GO:0006633; GO:0006952; GO:0009507; GO:0009534; GO:0009535; GO:0009536; GO:0009579; GO:0009611; GO:0009620; GO:0009695; GO:0009753; GO:0009941; GO:0009978; GO:0010287; GO:0016125; GO:0016491; GO:0016705; GO:0019373; GO:0019825; GO:0020037; GO:0031407; GO:0031408; GO:0050832 3159 XM_029340686.2 1203 728 613 1135 1426 F1R7R1 5.69e-76 Nonsense-mediated mRNA decay factor SMG5 (EST1-like protein B) (SMG-5 homolog) Danio rerio (Zebrafish) (Brachydanio rerio) chordate embryonic development [GO:0043009]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184] GO:0000184; GO:0005697; GO:0005737; GO:0042162; GO:0043009; GO:0070034 3160 XM_029340686.2 1203 728 613 1135 1426 F1R7R1 1.96e-45 Nonsense-mediated mRNA decay factor SMG5 (EST1-like protein B) (SMG-5 homolog) Danio rerio (Zebrafish) (Brachydanio rerio) chordate embryonic development [GO:0043009]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184] GO:0000184; GO:0005697; GO:0005737; GO:0042162; GO:0043009; GO:0070034 3161 XM_029341332.2 9 14 6 23 14 NA NA NA NA NA NA 3162 XM_029325332.2 1200 705 454 1226 903 NA NA NA NA NA NA 3163 XR_006395166.1 13 8 1 23 28 NA NA NA NA NA NA 3164 XM_029338551.2 2383 2277 1443 2374 1825 O49377 2.91e-41 Vesicle-associated membrane protein 711 (AtVAMP711) (v-SNARE synaptobrevin 7C) (AtVAMP7C) Arabidopsis thaliana (Mouse-ear cress) membrane fusion [GO:0061025]; protein transport [GO:0015031]; response to abscisic acid [GO:0009737]; response to salt stress [GO:0009651]; stomatal movement [GO:0010118]; vesicle-mediated transport [GO:0016192] GO:0000325; GO:0005774; GO:0005886; GO:0009651; GO:0009737; GO:0010118; GO:0015031; GO:0016192; GO:0061025 3165 XM_044328270.1 293 247 135 235 287 NA NA NA NA NA NA 3166 XM_029332682.2 462 635 317 348 417 Q6PHN7 1.21e-69 Transmembrane protein 164 Mus musculus (Mouse) positive regulation of ferroptosis [GO:0160020] GO:0016020; GO:0160020 3167 XM_029334081.2 364 336 252 307 758 P79955 6.13e-136 Carboxy-terminal kinesin 2 (XCTK2) Xenopus laevis (African clawed frog) microtubule-based movement [GO:0007018] GO:0003777; GO:0005524; GO:0005737; GO:0005874; GO:0007018; GO:0008017 3168 XM_044320220.1 1170 1074 365 710 1050 NA NA NA NA NA NA 3169 XR_006395456.1 85 0 31 4 7 NA NA NA NA NA NA 3170 XM_044318345.1 0 0 0 0 10 NA NA NA NA NA NA 3171 XM_044317351.1 37 0 0 0 0 NA NA NA NA NA NA 3172 XM_044309109.1 22 45 30 0 119 NA NA NA NA NA NA 3173 XR_006397533.1 60 13 110 36 231 NA NA NA NA NA NA 3174 XM_029326291.2 84 26 48 49 125 NA NA NA NA NA NA 3175 XM_029332393.2 53 79 9 103 33 Q8BG58 2.57e-71 Transmembrane prolyl 4-hydroxylase (P4H-TM) (EC 1.14.11.29) (Hypoxia-inducible factor prolyl hydroxylase 4) (HIF-PH4) (HIF-prolyl hydroxylase 4) (HPH-4) Mus musculus (Mouse) peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; regulation of erythrocyte differentiation [GO:0045646] GO:0004656; GO:0005506; GO:0005509; GO:0005783; GO:0005789; GO:0016706; GO:0018401; GO:0031418; GO:0045646 3176 XR_003828246.2 141 81 39 79 70 NA NA NA NA NA NA 3177 XM_029357353.2 281 61 86 69 174 Q5E9T8 1.14e-70 Mevalonate kinase (MK) (EC 2.7.1.36) Bos taurus (Bovine) cholesterol biosynthetic process [GO:0006695]; isopentenyl diphosphate biosynthetic process, mevalonate pathway [GO:0019287]; negative regulation of inflammatory response [GO:0050728]; phosphorylation [GO:0016310] GO:0000287; GO:0004496; GO:0005524; GO:0005777; GO:0005829; GO:0006695; GO:0016310; GO:0019287; GO:0042802; GO:0050728 3178 XM_029351387.2 13 66 74 13 175 NA NA NA NA NA NA 3179 XM_029357836.2 0 176 0 151 50 Q5XXP2 6.89e-28 Melanopsin (Opsin-4) Phodopus sungorus (Striped hairy-footed hamster) (Djungarian hamster) hyaloid vascular plexus regression [GO:1990384]; optokinetic behavior [GO:0007634]; phototransduction [GO:0007602]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511]; visual perception [GO:0007601] GO:0005502; GO:0005886; GO:0007601; GO:0007602; GO:0007634; GO:0008020; GO:0016020; GO:0030424; GO:0030425; GO:0042752; GO:0043204; GO:0048511; GO:1990384 3180 XR_006396106.1 63 50 0 23 243 NA NA NA NA NA NA 3181 XM_044316839.1 453 366 60 223 182 P80035 5.56e-86 Gastric triacylglycerol lipase (GL) (Gastric lipase) (EC 3.1.1.3) Canis lupus familiaris (Dog) (Canis familiaris) lipid catabolic process [GO:0016042] GO:0004806; GO:0005576; GO:0016042; GO:0043231 3182 XM_044322544.1 88 123 0 130 140 NA NA NA NA NA NA 3183 XM_044308495.1 103 63 58 202 62 Q60902 3.18e-32 Epidermal growth factor receptor substrate 15-like 1 (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs) (Eps15-related protein) (Eps15R) Mus musculus (Mouse) endocytosis [GO:0006897]; endosomal transport [GO:0016197] GO:0005509; GO:0005634; GO:0006897; GO:0016197; GO:0030132 3184 XM_029324563.2 2 0 12 21 7 NA NA NA NA NA NA 3185 XR_006392630.1 664 900 458 698 1203 Q91VS8 1.8e-130 FERM, ARHGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR) (FERM, RhoGEF and pleckstrin domain-containing protein 2) Mus musculus (Mouse) actin cytoskeleton reorganization [GO:0031532]; cell adhesion [GO:0007155]; hair cycle process [GO:0022405]; neuron remodeling [GO:0016322]; osteoclast differentiation [GO:0030316]; podosome assembly [GO:0071800]; Rac protein signal transduction [GO:0016601]; regulation of integrin activation [GO:0033623]; semaphorin-plexin signaling pathway [GO:0071526] GO:0005085; GO:0005737; GO:0005829; GO:0005856; GO:0007155; GO:0008092; GO:0016322; GO:0016601; GO:0022405; GO:0030316; GO:0031532; GO:0033623; GO:0071526; GO:0071800 3186 XR_006392630.1 664 900 458 698 1203 Q91VS8 1.8e-130 FERM, ARHGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR) (FERM, RhoGEF and pleckstrin domain-containing protein 2) Mus musculus (Mouse) actin cytoskeleton reorganization [GO:0031532]; cell adhesion [GO:0007155]; hair cycle process [GO:0022405]; neuron remodeling [GO:0016322]; osteoclast differentiation [GO:0030316]; podosome assembly [GO:0071800]; Rac protein signal transduction [GO:0016601]; regulation of integrin activation [GO:0033623]; semaphorin-plexin signaling pathway [GO:0071526] GO:0005085; GO:0005737; GO:0005829; GO:0005856; GO:0007155; GO:0008092; GO:0016322; GO:0016601; GO:0022405; GO:0030316; GO:0031532; GO:0033623; GO:0071526; GO:0071800 3187 XR_006392630.1 664 900 458 698 1203 Q91VS8 1.8e-130 FERM, ARHGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR) (FERM, RhoGEF and pleckstrin domain-containing protein 2) Mus musculus (Mouse) actin cytoskeleton reorganization [GO:0031532]; cell adhesion [GO:0007155]; hair cycle process [GO:0022405]; neuron remodeling [GO:0016322]; osteoclast differentiation [GO:0030316]; podosome assembly [GO:0071800]; Rac protein signal transduction [GO:0016601]; regulation of integrin activation [GO:0033623]; semaphorin-plexin signaling pathway [GO:0071526] GO:0005085; GO:0005737; GO:0005829; GO:0005856; GO:0007155; GO:0008092; GO:0016322; GO:0016601; GO:0022405; GO:0030316; GO:0031532; GO:0033623; GO:0071526; GO:0071800 3188 XR_006392630.1 664 900 458 698 1203 Q91VS8 4.72e-72 FERM, ARHGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR) (FERM, RhoGEF and pleckstrin domain-containing protein 2) Mus musculus (Mouse) actin cytoskeleton reorganization [GO:0031532]; cell adhesion [GO:0007155]; hair cycle process [GO:0022405]; neuron remodeling [GO:0016322]; osteoclast differentiation [GO:0030316]; podosome assembly [GO:0071800]; Rac protein signal transduction [GO:0016601]; regulation of integrin activation [GO:0033623]; semaphorin-plexin signaling pathway [GO:0071526] GO:0005085; GO:0005737; GO:0005829; GO:0005856; GO:0007155; GO:0008092; GO:0016322; GO:0016601; GO:0022405; GO:0030316; GO:0031532; GO:0033623; GO:0071526; GO:0071800 3189 XR_006392630.1 664 900 458 698 1203 Q91VS8 4.72e-72 FERM, ARHGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR) (FERM, RhoGEF and pleckstrin domain-containing protein 2) Mus musculus (Mouse) actin cytoskeleton reorganization [GO:0031532]; cell adhesion [GO:0007155]; hair cycle process [GO:0022405]; neuron remodeling [GO:0016322]; osteoclast differentiation [GO:0030316]; podosome assembly [GO:0071800]; Rac protein signal transduction [GO:0016601]; regulation of integrin activation [GO:0033623]; semaphorin-plexin signaling pathway [GO:0071526] GO:0005085; GO:0005737; GO:0005829; GO:0005856; GO:0007155; GO:0008092; GO:0016322; GO:0016601; GO:0022405; GO:0030316; GO:0031532; GO:0033623; GO:0071526; GO:0071800 3190 XR_006396757.1 3 83 2 18 23 NA NA NA NA NA NA 3191 XM_044312997.1 21 0 0 0 8 NA NA NA NA NA NA 3192 XR_006393233.1 3 92 144 93 20 NA NA NA NA NA NA 3193 XM_029346967.2 11 16 19 33 9 O54956 0 DNA polymerase epsilon subunit 2 (DNA polymerase II subunit 2) (DNA polymerase epsilon subunit B) Mus musculus (Mouse) DNA-templated DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276] GO:0003677; GO:0005654; GO:0006261; GO:0008622; GO:0016604; GO:0042276; GO:0043231 3194 XM_029338307.2 241 218 228 137 313 Q6DGR4 2.05e-89 Protein HGH1 homolog Danio rerio (Zebrafish) (Brachydanio rerio) NA NA 3195 XM_029327761.2 19 9 5 3 39 NA NA NA NA NA NA 3196 XM_044325554.1 10 0 4 3 41 NA NA NA NA NA NA 3197 XM_044324290.1 30 139 95 76 11 P60882 0 Multiple epidermal growth factor-like domains protein 8 (Multiple EGF-like domains protein 8) (Epidermal growth factor-like protein 4) (EGF-like protein 4) Mus musculus (Mouse) animal organ morphogenesis [GO:0009887]; BMP signaling pathway [GO:0030509]; cell migration involved in gastrulation [GO:0042074]; coronary vasculature development [GO:0060976]; craniofacial suture morphogenesis [GO:0097094]; determination of digestive tract left/right asymmetry [GO:0071907]; determination of heart left/right asymmetry [GO:0061371]; determination of left/right symmetry [GO:0007368]; embryonic heart tube left/right pattern formation [GO:0060971]; embryonic heart tube morphogenesis [GO:0003143]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; epiboly involved in gastrulation with mouth forming second [GO:0055113]; fasciculation of sensory neuron axon [GO:0097155]; left/right pattern formation [GO:0060972]; limb morphogenesis [GO:0035108]; negative regulation of smoothened signaling pathway [GO:0045879]; positive regulation of axon extension involved in axon guidance [GO:0048842]; regulation of gene expression [GO:0010468]; tissue development [GO:0009888] GO:0003143; GO:0005509; GO:0005634; GO:0007368; GO:0009887; GO:0009888; GO:0010468; GO:0016020; GO:0030326; GO:0030509; GO:0035108; GO:0042074; GO:0045879; GO:0048704; GO:0048842; GO:0055113; GO:0060971; GO:0060972; GO:0060976; GO:0061371; GO:0071907; GO:0097094; GO:0097155 3198 XM_044322840.1 197 280 171 37 136 NA NA NA NA NA NA 3199 XM_044319248.1 1223 1115 879 696 855 Q9R0R1 4.05e-61 Melanotransferrin (Membrane-bound transferrin-like protein p97) (MTf) (CD antigen CD228) Mus musculus (Mouse) iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of plasminogen activation [GO:0010756] GO:0005506; GO:0005615; GO:0005769; GO:0005886; GO:0006826; GO:0009986; GO:0010756; GO:0055037; GO:0055072; GO:0090091; GO:1900025 3200 XM_044319248.1 1223 1115 879 696 855 Q9R0R1 2.45e-47 Melanotransferrin (Membrane-bound transferrin-like protein p97) (MTf) (CD antigen CD228) Mus musculus (Mouse) iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of plasminogen activation [GO:0010756] GO:0005506; GO:0005615; GO:0005769; GO:0005886; GO:0006826; GO:0009986; GO:0010756; GO:0055037; GO:0055072; GO:0090091; GO:1900025 3201 XM_044320195.1 0 0 0 0 75 Q9LQV2 4.99e-50 RNA-dependent RNA polymerase 1 (AtRDRP1) (EC 2.7.7.48) (RNA-directed RNA polymerase 1) Arabidopsis thaliana (Mouse-ear cress) defense response [GO:0006952]; positive regulation of post-transcriptional gene silencing [GO:0060148]; response to salicylic acid [GO:0009751]; response to virus [GO:0009615]; siRNA processing [GO:0030422]; wax biosynthetic process [GO:0010025] GO:0003723; GO:0003968; GO:0006952; GO:0009615; GO:0009751; GO:0010025; GO:0030422; GO:0031380; GO:0060148 3202 XM_029339076.2 523 303 184 428 114 Q8N653 1.04e-24 Leucine-zipper-like transcriptional regulator 1 (LZTR-1) Homo sapiens (Human) negative regulation of Ras protein signal transduction [GO:0046580]; protein ubiquitination [GO:0016567] GO:0005794; GO:0012505; GO:0016567; GO:0031267; GO:0031463; GO:0046580; GO:0055038 3203 XR_003825925.1 0 1 12 2 34 NA NA NA NA NA NA 3204 XR_006396389.1 42 2122 14 4 594 NA NA NA NA NA NA 3205 XM_029329178.2 118 213 87 169 165 NA NA NA NA NA NA 3206 XM_044313226.1 19 3 17 12 128 NA NA NA NA NA NA 3207 XM_044327231.1 34 37 4 19 17 Q96RW7 2.38e-25 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 3208 XM_044328841.1 444 696 322 189 1258 NA NA NA NA NA NA 3209 XM_029350108.2 2109 1816 1153 2161 1859 Q8K135 1.53e-176 Dyslexia-associated protein KIAA0319-like protein (Adeno-associated virus receptor) (AAVR) Mus musculus (Mouse) acrosome assembly [GO:0001675]; flagellated sperm motility [GO:0030317]; neuron migration [GO:0001764]; proacrosomal vesicle fusion [GO:0120211]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; response to auditory stimulus [GO:0010996]; spermatogenesis [GO:0007283] GO:0000139; GO:0001675; GO:0001764; GO:0005730; GO:0005794; GO:0005802; GO:0005886; GO:0007283; GO:0010996; GO:0016020; GO:0019065; GO:0030317; GO:0031410; GO:0120211 3210 XM_044324125.1 11 0 14 1 64 NA NA NA NA NA NA 3211 XM_044319459.1 177 39 107 293 355 Q6V0I7 0 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3212 XM_044319459.1 177 39 107 293 355 Q6V0I7 0 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3213 XM_044319459.1 177 39 107 293 355 Q6V0I7 0 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3214 XM_044319459.1 177 39 107 293 355 Q6V0I7 0 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3215 XM_044319459.1 177 39 107 293 355 Q6V0I7 0 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3216 XM_044319459.1 177 39 107 293 355 Q6V0I7 0 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3217 XM_044319459.1 177 39 107 293 355 Q6V0I7 0 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3218 XM_044319459.1 177 39 107 293 355 Q6V0I7 0 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3219 XM_044319459.1 177 39 107 293 355 Q6V0I7 3.53e-164 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3220 XM_044319459.1 177 39 107 293 355 Q6V0I7 5.85e-143 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3221 XM_044319459.1 177 39 107 293 355 Q6V0I7 1.79e-135 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3222 XM_044319459.1 177 39 107 293 355 Q6V0I7 1.83e-99 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3223 XM_044319459.1 177 39 107 293 355 Q6V0I7 1.16e-94 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3224 XM_044319459.1 177 39 107 293 355 Q6V0I7 4.15e-86 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3225 XM_044319459.1 177 39 107 293 355 Q6V0I7 3.39e-84 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3226 XM_044319459.1 177 39 107 293 355 Q6V0I7 3.64e-59 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3227 XM_044319459.1 177 39 107 293 355 Q6V0I7 4.08e-56 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3228 XM_044319459.1 177 39 107 293 355 Q6V0I7 8.66e-56 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3229 XM_044319459.1 177 39 107 293 355 Q6V0I7 9.67e-55 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3230 XM_044319459.1 177 39 107 293 355 Q6V0I7 1.35e-54 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3231 XM_044319459.1 177 39 107 293 355 Q6V0I7 5.48e-54 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3232 XM_044319459.1 177 39 107 293 355 Q6V0I7 5.57e-54 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3233 XM_044319459.1 177 39 107 293 355 Q6V0I7 3.55e-52 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3234 XM_044319459.1 177 39 107 293 355 Q6V0I7 3.39e-48 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3235 XM_044319459.1 177 39 107 293 355 Q6V0I7 7.08e-48 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3236 XM_044319459.1 177 39 107 293 355 Q6V0I7 1.74e-47 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3237 XM_044319459.1 177 39 107 293 355 Q6V0I7 4.4e-46 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3238 XM_044319459.1 177 39 107 293 355 Q6V0I7 2.11e-45 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3239 XM_044319459.1 177 39 107 293 355 Q6V0I7 3.08e-43 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3240 XM_044319459.1 177 39 107 293 355 Q6V0I7 1.02e-42 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3241 XM_044319459.1 177 39 107 293 355 Q6V0I7 2.78e-42 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3242 XM_044319459.1 177 39 107 293 355 Q6V0I7 5.49e-42 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3243 XM_044319459.1 177 39 107 293 355 Q6V0I7 1.99e-40 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3244 XM_044319459.1 177 39 107 293 355 Q6V0I7 2.38e-40 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3245 XM_044319459.1 177 39 107 293 355 Q6V0I7 2.5e-39 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3246 XM_044319459.1 177 39 107 293 355 Q6V0I7 1.19e-37 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3247 XM_044319459.1 177 39 107 293 355 Q6V0I7 1.25e-37 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3248 XM_044319459.1 177 39 107 293 355 Q6V0I7 2.96e-37 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3249 XM_044319459.1 177 39 107 293 355 Q6V0I7 3.04e-36 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3250 XM_044319459.1 177 39 107 293 355 Q6V0I7 4.07e-35 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3251 XM_044319459.1 177 39 107 293 355 Q6V0I7 7.51e-34 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3252 XM_044319459.1 177 39 107 293 355 Q6V0I7 3.45e-33 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3253 XM_044319459.1 177 39 107 293 355 Q6V0I7 9.42e-32 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3254 XM_044319459.1 177 39 107 293 355 Q6V0I7 1.07e-31 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3255 XM_044319459.1 177 39 107 293 355 Q6V0I7 2.16e-31 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3256 XM_044319459.1 177 39 107 293 355 Q6V0I7 3.37e-28 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3257 XM_044319459.1 177 39 107 293 355 Q6V0I7 3.78e-28 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 3258 XR_006395703.1 85 400 97 185 483 NA NA NA NA NA NA 3259 XM_044307361.1 368 116 344 80 54 Q7RTR2 3.55e-58 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 3260 XM_044307361.1 368 116 344 80 54 Q7RTR2 2.34e-57 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 3261 XM_044307361.1 368 116 344 80 54 Q7RTR2 2.38e-48 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 3262 XM_044307361.1 368 116 344 80 54 Q7RTR2 3.49e-27 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 3263 XM_029336181.2 309 65 0 133 0 Q61603 4.6e-66 Glycine receptor subunit alpha-4 Mus musculus (Mouse) chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; neuropeptide signaling pathway [GO:0007218]; regulation of membrane potential [GO:0042391]; response to amino acid [GO:0043200]; signal transduction [GO:0007165]; synaptic transmission, glycinergic [GO:0060012] GO:0004888; GO:0005231; GO:0005886; GO:0007165; GO:0007218; GO:0007268; GO:0016594; GO:0016934; GO:0030425; GO:0030594; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0043200; GO:0043204; GO:0045202; GO:0050877; GO:0060012; GO:0098690; GO:0099634; GO:1902476; GO:1904315 3264 XR_003827131.2 9 10 0 0 2 NA NA NA NA NA NA 3265 XM_029357207.2 86 52 30 59 147 A2VDD2 2.63e-26 Dynein light chain Tctex-type 5-B (Tctex1 domain-containing protein 1-B) Xenopus laevis (African clawed frog) NA NA 3266 XM_044321108.1 8 14 27 12 32 A1L1W9 6.01e-43 Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10) Danio rerio (Zebrafish) (Brachydanio rerio) aromatic amino acid transport [GO:0015801]; thyroid hormone transport [GO:0070327] GO:0005302; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0070327 3267 XM_029334934.2 847 947 764 1411 1101 NA NA NA NA NA NA 3268 XM_029348333.2 23 6 32 6 109 NA NA NA NA NA NA 3269 XR_006398106.1 440 446 172 330 440 NA NA NA NA NA NA 3270 XM_044308001.1 8 16 19 8 38 NA NA NA NA NA NA 3271 XM_044317255.1 11 5 17 42 125 Q80UK0 1.39e-50 SEC14 domain and spectrin repeat-containing protein 1 (Huntingtin-interacting protein-like protein) Mus musculus (Mouse) negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel [GO:1904878] GO:0005546; GO:0010314; GO:0032266; GO:0034704; GO:0043325; GO:0045111; GO:0070273; GO:0070300; GO:0080025; GO:1904878 3272 XM_044308382.1 75 143 50 154 89 NA NA NA NA NA NA 3273 XM_044329069.1 480 194 209 35 190 P16157 7.81e-78 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 3274 XM_044329069.1 480 194 209 35 190 P16157 1.35e-61 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 3275 XM_044329069.1 480 194 209 35 190 P16157 1.32e-59 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 3276 XM_044329069.1 480 194 209 35 190 P16157 9.4e-38 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 3277 XM_044320000.1 270 25 0 27 0 Q8BT60 0 Copine-3 (Copine III) Mus musculus (Mouse) cellular response to calcium ion [GO:0071277]; cellular response to growth factor stimulus [GO:0071363]; ERBB2 signaling pathway [GO:0038128]; positive regulation of cell migration [GO:0030335] GO:0004674; GO:0005544; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005739; GO:0005829; GO:0005886; GO:0005925; GO:0030054; GO:0030335; GO:0030971; GO:0038128; GO:0046872; GO:0048306; GO:0071277; GO:0071363 3278 XM_044319350.1 111 144 78 210 120 Q1RMU2 2.68e-101 Ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.4.19.12) (Deubiquitinating enzyme CYLD) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD) Bos taurus (Bovine) innate immune response [GO:0045087]; necroptotic process [GO:0070266]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-18-mediated signaling pathway [GO:2000493]; negative regulation of JNK cascade [GO:0046329]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of p38MAPK cascade [GO:1903753]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; protein deubiquitination [GO:0016579]; protein K63-linked deubiquitination [GO:0070536]; protein linear deubiquitination [GO:1990108]; regulation of cilium assembly [GO:1902017]; regulation of inflammatory response [GO:0050727]; regulation of intrinsic apoptotic signaling pathway [GO:2001242]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of mitotic cell cycle [GO:0007346]; regulation of necroptotic process [GO:0060544]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt signaling pathway [GO:0016055] GO:0004843; GO:0005813; GO:0005819; GO:0005829; GO:0005881; GO:0006511; GO:0007346; GO:0008270; GO:0010803; GO:0016055; GO:0016579; GO:0019901; GO:0030496; GO:0031234; GO:0032088; GO:0036064; GO:0045087; GO:0046329; GO:0048471; GO:0050727; GO:0050728; GO:0060544; GO:0061578; GO:0070064; GO:0070266; GO:0070507; GO:0070536; GO:0090090; GO:0097542; GO:1901223; GO:1902017; GO:1903753; GO:1990108; GO:2000493; GO:2001238; GO:2001242 3279 XM_044318715.1 613 322 297 375 457 Q5F362 1.21e-100 Cell cycle control protein 50A (P4-ATPase flippase complex beta subunit TMEM30A) (Transmembrane protein 30A) Gallus gallus (Chicken) phospholipid translocation [GO:0045332] GO:0001750; GO:0001917; GO:0005783; GO:0005794; GO:0005886; GO:0016324; GO:0030658; GO:0045332; GO:1990531 3280 XM_044315785.1 32 18 16 0 11 NA NA NA NA NA NA 3281 XM_029334724.2 8 0 0 0 0 Q9C0E8 1.31e-55 Endoplasmic reticulum junction formation protein lunapark (ER junction formation factor lunapark) Homo sapiens (Human) blood coagulation [GO:0007596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum tubular network maintenance [GO:0071788]; endoplasmic reticulum tubular network organization [GO:0071786]; limb development [GO:0060173]; positive regulation of endoplasmic reticulum tubular network organization [GO:1903373]; regulation of chondrocyte differentiation [GO:0032330] GO:0005654; GO:0005783; GO:0005789; GO:0007029; GO:0007596; GO:0016020; GO:0032330; GO:0035115; GO:0042733; GO:0042802; GO:0046872; GO:0060173; GO:0071782; GO:0071786; GO:0071788; GO:0098826; GO:1903373 3282 XM_029329683.2 195 126 183 226 301 F4IF36 2.01e-118 Protein FORGETTER 1 (Protein EMBRYO DEFECTIVE 1135) Arabidopsis thaliana (Mouse-ear cress) chromatin remodeling [GO:0006338]; epigenetic regulation of gene expression [GO:0040029]; heat acclimation [GO:0010286]; positive regulation of cellular response to heat [GO:1900036]; regulation of DNA-templated transcription [GO:0006355]; response to heat [GO:0009408] GO:0005634; GO:0006338; GO:0006355; GO:0009408; GO:0010286; GO:0031490; GO:0040029; GO:0042393; GO:0046872; GO:1900036; GO:1990841 3283 XM_029329683.2 195 126 183 226 301 F4IF36 9.19e-103 Protein FORGETTER 1 (Protein EMBRYO DEFECTIVE 1135) Arabidopsis thaliana (Mouse-ear cress) chromatin remodeling [GO:0006338]; epigenetic regulation of gene expression [GO:0040029]; heat acclimation [GO:0010286]; positive regulation of cellular response to heat [GO:1900036]; regulation of DNA-templated transcription [GO:0006355]; response to heat [GO:0009408] GO:0005634; GO:0006338; GO:0006355; GO:0009408; GO:0010286; GO:0031490; GO:0040029; GO:0042393; GO:0046872; GO:1900036; GO:1990841 3284 XM_044323861.1 0 0 22 414 39 NA NA NA NA NA NA 3285 XM_029332636.2 57 100 42 83 34 Q8VCK5 1.24e-102 Kelch-like protein 20 (Kelch-like ECT2-interacting protein) Mus musculus (Mouse) Golgi to endosome transport [GO:0006895]; negative regulation of apoptotic process [GO:0043066]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K33-linked ubiquitination [GO:1990390]; protein transport [GO:0015031]; protein ubiquitination [GO:0016567] GO:0003779; GO:0004842; GO:0005737; GO:0005794; GO:0005802; GO:0005829; GO:0006895; GO:0015031; GO:0016567; GO:0016605; GO:0019964; GO:0030424; GO:0030425; GO:0031463; GO:0043066; GO:0043161; GO:0048471; GO:1990390 3286 XM_044319962.1 0 119 88 0 0 Q8MIQ9 2.61e-126 P protein (Melanocyte-specific transporter protein) (Pink-eyed dilution protein homolog) Sus scrofa (Pig) lysosomal lumen pH elevation [GO:0035752]; melanin biosynthetic process [GO:0042438]; melanin biosynthetic process from tyrosine [GO:0006583]; melanocyte differentiation [GO:0030318] GO:0006583; GO:0030318; GO:0033162; GO:0035752; GO:0042438; GO:0061778 3287 XM_044312832.1 13 4 6 2 22 Q5RB83 2.1e-43 Phosphoserine phosphatase (PSP) (PSPase) (EC 3.1.3.3) (O-phosphoserine phosphohydrolase) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) L-serine biosynthetic process [GO:0006564]; L-serine metabolic process [GO:0006563] GO:0000287; GO:0005829; GO:0006563; GO:0006564; GO:0036424 3288 XM_044314840.1 3837 2618 2180 3592 4750 Q5R416 0 Catenin alpha-2 (Alpha N-catenin) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) axonogenesis [GO:0007409]; brain morphogenesis [GO:0048854]; cell-cell adhesion [GO:0098609]; dendrite morphogenesis [GO:0048813]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; prepulse inhibition [GO:0060134]; radial glia guided migration of Purkinje cell [GO:0021942]; regulation of neuron migration [GO:2001222]; regulation of neuron projection development [GO:0010975]; regulation of synapse structural plasticity [GO:0051823] GO:0005198; GO:0005634; GO:0005737; GO:0005886; GO:0005912; GO:0007409; GO:0010975; GO:0015629; GO:0021942; GO:0030424; GO:0034316; GO:0045296; GO:0048813; GO:0048854; GO:0051015; GO:0051823; GO:0060134; GO:0098609; GO:2001222 3289 XM_044314840.1 3837 2618 2180 3592 4750 Q5R416 1.37e-69 Catenin alpha-2 (Alpha N-catenin) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) axonogenesis [GO:0007409]; brain morphogenesis [GO:0048854]; cell-cell adhesion [GO:0098609]; dendrite morphogenesis [GO:0048813]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; prepulse inhibition [GO:0060134]; radial glia guided migration of Purkinje cell [GO:0021942]; regulation of neuron migration [GO:2001222]; regulation of neuron projection development [GO:0010975]; regulation of synapse structural plasticity [GO:0051823] GO:0005198; GO:0005634; GO:0005737; GO:0005886; GO:0005912; GO:0007409; GO:0010975; GO:0015629; GO:0021942; GO:0030424; GO:0034316; GO:0045296; GO:0048813; GO:0048854; GO:0051015; GO:0051823; GO:0060134; GO:0098609; GO:2001222 3290 XM_029357386.2 9035 9117 4688 7071 6976 P62752 4.11e-64 60S ribosomal protein L23a Rattus norvegicus (Rat) ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412] GO:0000027; GO:0003735; GO:0005634; GO:0006412; GO:0022625; GO:0022626; GO:0045202; GO:0070180; GO:1904841 3291 XM_044307720.1 54 191 43 186 65 Q9NQT4 9.28e-41 Exosome complex component RRP46 (Chronic myelogenous leukemia tumor antigen 28) (Exosome component 5) (Ribosomal RNA-processing protein 46) (p12B) Homo sapiens (Human) defense response to virus [GO:0051607]; DNA deamination [GO:0045006]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; nuclear mRNA surveillance [GO:0071028]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; U4 snRNA 3'-end processing [GO:0034475] GO:0000175; GO:0000176; GO:0000177; GO:0000178; GO:0000791; GO:0003723; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0006364; GO:0006396; GO:0006401; GO:0016075; GO:0034427; GO:0034475; GO:0043928; GO:0045006; GO:0051607; GO:0071028; GO:0071051; GO:0101019 3292 XM_044314655.1 0 0 8 20 2 NA NA NA NA NA NA 3293 XR_006397004.1 0 0 0 10 0 NA NA NA NA NA NA 3294 XM_044307779.1 874 620 547 879 1414 O60306 0 RNA helicase aquarius (EC 3.6.4.13) (Intron-binding protein of 160 kDa) (IBP160) Homo sapiens (Human) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0003723; GO:0003727; GO:0003729; GO:0005524; GO:0005634; GO:0005654; GO:0016020; GO:0016887; GO:0034458; GO:0071007; GO:0071013 3295 XM_029358258.2 0 55 0 0 2 Q9NXS3 6.92e-160 Kelch-like protein 28 (BTB/POZ domain-containing protein 5) Homo sapiens (Human) NA NA 3296 XM_044308485.1 5 0 30 58 32 NA NA NA NA NA NA 3297 XM_044311131.1 0 0 17 75 2 NA NA NA NA NA NA 3298 XM_029338193.2 426 465 433 331 219 A4II73 4.74e-56 Esterase OVCA2 (EC 3.1.2.-) (Ovarian cancer-associated gene 2 protein homolog) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0016787 3299 XM_044324496.1 101 0 0 105 156 NA NA NA NA NA NA 3300 XM_029343989.2 1846 1228 1010 1334 1381 Q3ZBH3 1.63e-46 CD151 antigen (CD antigen CD151) Bos taurus (Bovine) cell migration [GO:0016477] GO:0005178; GO:0005886; GO:0016477 3301 XM_044326463.1 0 0 0 0 37 P25931 1.36e-23 RYamide receptor (Neuropeptide Y-like receptor) (NPY-R) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218] GO:0001653; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0016020 3302 XM_044322460.1 4 26 0 48 4 Q96AY4 5.26e-82 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3303 XM_044322460.1 4 26 0 48 4 Q96AY4 1.22e-80 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3304 XM_044322460.1 4 26 0 48 4 Q96AY4 5.48e-77 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3305 XM_044322460.1 4 26 0 48 4 Q96AY4 8.81e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3306 XM_044322460.1 4 26 0 48 4 Q96AY4 1.83e-62 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3307 XM_044322460.1 4 26 0 48 4 Q96AY4 1.13e-49 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3308 XM_029340225.2 549 711 482 333 664 NA NA NA NA NA NA 3309 XM_029351251.2 430 137 303 289 476 NA NA NA NA NA NA 3310 XM_029353081.2 16 9 19 26 28 NA NA NA NA NA NA 3311 XR_006392982.1 41 2 25 5 151 NA NA NA NA NA NA 3312 XM_029329364.2 468 87 232 741 641 Q96BD0 2.69e-102 Solute carrier organic anion transporter family member 4A1 (OATP4A1) (Colon organic anion transporter) (Organic anion transporter polypeptide-related protein 1) (OATP-RP1) (OATPRP1) (POAT) (Organic anion-transporting polypeptide E) (OATP-E) (Sodium-independent organic anion transporter E) (Solute carrier family 21 member 12) Homo sapiens (Human) sodium-independent organic anion transport [GO:0043252] GO:0005886; GO:0008514; GO:0015132; GO:0015347; GO:0015349; GO:0043252 3313 XM_029330089.2 519 390 388 474 654 Q4R8V8 8.32e-56 Cilia- and flagella-associated protein 100 (Coiled-coil domain-containing protein 37) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) cilium movement [GO:0003341]; inner dynein arm assembly [GO:0036159] GO:0003341; GO:0031514; GO:0036159; GO:0070840; GO:0097545 3314 XM_029330089.2 519 390 388 474 654 Q4R8V8 1.79e-37 Cilia- and flagella-associated protein 100 (Coiled-coil domain-containing protein 37) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) cilium movement [GO:0003341]; inner dynein arm assembly [GO:0036159] GO:0003341; GO:0031514; GO:0036159; GO:0070840; GO:0097545 3315 XM_044309446.1 5 0 0 4 9 NA NA NA NA NA NA 3316 XM_044326515.1 48 85 160 44 136 NA NA NA NA NA NA 3317 XM_044323155.1 169 35 172 162 464 P22897 1.43e-115 Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0001618; GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 3318 XM_044323155.1 169 35 172 162 464 P22897 7.68e-98 Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0001618; GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 3319 XM_044323155.1 169 35 172 162 464 P22897 2.13e-84 Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0001618; GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 3320 XM_044323155.1 169 35 172 162 464 P22897 2.25e-62 Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0001618; GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 3321 XM_044323155.1 169 35 172 162 464 P22897 3.05e-53 Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0001618; GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 3322 XM_044323155.1 169 35 172 162 464 P22897 1.71e-32 Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0001618; GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 3323 XM_044323155.1 169 35 172 162 464 P22897 8.82e-32 Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0001618; GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 3324 XM_044323155.1 169 35 172 162 464 P22897 6.04e-30 Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0001618; GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 3325 XM_044323155.1 169 35 172 162 464 P22897 4.82e-27 Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0001618; GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 3326 XR_006397316.1 51 19 13 28 56 NA NA NA NA NA NA 3327 XM_044324346.1 24 0 0 20 0 NA NA NA NA NA NA 3328 XR_006398137.1 8 19 45 92 93 NA NA NA NA NA NA 3329 XM_044328039.1 388 300 195 324 149 NA NA NA NA NA NA 3330 XM_044325323.1 0 5 0 3 22 NA NA NA NA NA NA 3331 XM_044314288.1 34 0 30 21 13 P81274 2.4e-41 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 3332 XM_044314288.1 34 0 30 21 13 P81274 4.19e-38 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 3333 XM_044314288.1 34 0 30 21 13 P81274 5.28e-35 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 3334 XM_044314288.1 34 0 30 21 13 P81274 6.22e-30 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 3335 XM_029349870.2 183 91 66 55 406 P50211 1.82e-122 Insulin gene enhancer protein ISL-1 (Islet-1) Gallus gallus (Chicken) atrial septum morphogenesis [GO:0060413]; axonogenesis [GO:0007409]; canonical Wnt signaling pathway [GO:0060070]; cardiac cell fate determination [GO:0060913]; cardiac muscle cell myoblast differentiation [GO:0060379]; cardiac right ventricle morphogenesis [GO:0003215]; cell population proliferation [GO:0008283]; endocardial cushion morphogenesis [GO:0003203]; heart development [GO:0007507]; innervation [GO:0060384]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural crest cell migration [GO:0001755]; neuron fate specification [GO:0048665]; outflow tract septum morphogenesis [GO:0003148]; pancreas development [GO:0031016]; peripheral nervous system neuron axonogenesis [GO:0048936]; pharyngeal system development [GO:0060037]; pituitary gland development [GO:0021983]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA binding [GO:0043388]; positive regulation of granulocyte colony-stimulating factor production [GO:0071657]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of histone acetylation [GO:0035066]; positive regulation of insulin secretion [GO:0032024]; positive regulation of interleukin-1 alpha production [GO:0032730]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type II interferon production [GO:0032729]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of secondary heart field cardioblast proliferation [GO:0003266]; regulation of transcription by RNA polymerase II [GO:0006357]; retinal ganglion cell axon guidance [GO:0031290]; secondary heart field specification [GO:0003139]; sensory system development [GO:0048880]; sinoatrial node cell development [GO:0060931]; spinal cord motor neuron cell fate specification [GO:0021520]; transcription by RNA polymerase II [GO:0006366]; trigeminal nerve development [GO:0021559]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; visceral motor neuron differentiation [GO:0021524] GO:0000122; GO:0000785; GO:0000978; GO:0000981; GO:0000987; GO:0001228; GO:0001755; GO:0003139; GO:0003148; GO:0003203; GO:0003215; GO:0003266; GO:0005634; GO:0006357; GO:0006366; GO:0007409; GO:0007507; GO:0008283; GO:0008284; GO:0010575; GO:0021520; GO:0021524; GO:0021559; GO:0021983; GO:0031016; GO:0031290; GO:0032024; GO:0032725; GO:0032729; GO:0032730; GO:0032731; GO:0032735; GO:0032755; GO:0032760; GO:0035066; GO:0042531; GO:0043388; GO:0043425; GO:0043524; GO:0045597; GO:0045665; GO:0045766; GO:0045892; GO:0045944; GO:0046872; GO:0048665; GO:0048880; GO:0048936; GO:0050728; GO:0055010; GO:0060037; GO:0060070; GO:0060379; GO:0060384; GO:0060413; GO:0060913; GO:0060931; GO:0061629; GO:0071657; GO:0086091; GO:0090090; GO:1990841 3336 XM_044323557.1 0 1 7 6 24 NA NA NA NA NA NA 3337 XM_044311060.1 20 0 5 0 20 NA NA NA NA NA NA 3338 XM_044327508.1 25 26 0 61 61 Q3V1V3 4.3e-96 ESF1 homolog (ABT1-associated protein) Mus musculus (Mouse) rRNA processing [GO:0006364] GO:0003723; GO:0005654; GO:0005730; GO:0006364 3339 XM_029354066.2 1176 1053 0 998 995 NA NA NA NA NA NA 3340 XM_044319355.1 1816 860 776 1538 1723 B8V7Q1 0 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 3341 XM_044319355.1 1816 860 776 1538 1723 B8V7Q1 0 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 3342 XM_029332640.2 101 62 76 109 140 E7F7V7 1.84e-21 Galanin receptor 2b Danio rerio (Zebrafish) (Brachydanio rerio) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; neuropeptide signaling pathway [GO:0007218] GO:0004966; GO:0005886; GO:0007188; GO:0007218; GO:0008528 3343 XM_044309083.1 13 11 0 50 15 NA NA NA NA NA NA 3344 XM_029351701.2 631 567 341 616 1012 NA NA NA NA NA NA 3345 XM_029341870.2 3816 3389 2435 2788 3417 Q28653 0 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PP2A B subunit isoform B'-delta) (PP2A B subunit isoform B'-gamma) (PP2A B subunit isoform B56-delta) (PP2A B subunit isoform PR61-delta) (PP2A B subunit isoform R5-delta) Oryctolagus cuniculus (Rabbit) signal transduction [GO:0007165] GO:0000159; GO:0005634; GO:0007165; GO:0019888 3346 XM_029339367.2 227 233 280 409 223 NA NA NA NA NA NA 3347 XM_029346466.2 5797 5061 3241 5758 4795 NA NA NA NA NA NA 3348 XM_044311771.1 41 0 46 1 107 P84239 1.01e-69 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 3349 XM_044307729.1 0 2 2 0 6 NA NA NA NA NA NA 3350 XM_029343587.2 11 0 20 12 11 NA NA NA NA NA NA 3351 XM_044316580.1 309 182 131 186 277 Q5ZML9 2.08e-137 Actin-histidine N-methyltransferase (EC 2.1.1.85) (Protein-L-histidine N-tele-methyltransferase) (SET domain-containing protein 3) Gallus gallus (Chicken) actin modification [GO:0030047]; peptidyl-histidine methylation [GO:0018021]; peptidyl-lysine dimethylation [GO:0018027]; peptidyl-lysine monomethylation [GO:0018026]; peptidyl-lysine trimethylation [GO:0018023]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0003713; GO:0003779; GO:0005737; GO:0016279; GO:0018021; GO:0018023; GO:0018026; GO:0018027; GO:0018064; GO:0030047; GO:0042800; GO:0045893; GO:0045944; GO:0046975 3352 XM_044322693.1 19 47 20 60 55 D8VNS8 2.18e-70 Ryncolin-2 Cerberus rynchops (Dog-faced water snake) NA GO:0005576; GO:0090729 3353 XR_006395223.1 23 0 7 17 7 NA NA NA NA NA NA 3354 XM_044315611.1 0 3 4 0 21 NA NA NA NA NA NA 3355 XM_029330556.2 2360 3764 2994 7135 5464 NA NA NA NA NA NA 3356 XM_044326846.1 0 0 0 10 1 NA NA NA NA NA NA 3357 XR_006394156.1 0 10 8 0 7 NA NA NA NA NA NA 3358 XR_003827200.2 14 11 0 13 8 NA NA NA NA NA NA 3359 XM_029357716.2 257 114 117 141 216 NA NA NA NA NA NA 3360 XM_029338434.2 460 656 672 663 333 A4QNN3 7.93e-75 Ubiquitin carboxyl-terminal hydrolase 30 (EC 3.4.19.12) (Deubiquitinating enzyme 30) (Ubiquitin thioesterase 30) (Ubiquitin-specific-processing protease 30) (Ub-specific protease 30) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) autophagy of mitochondrion [GO:0000422]; mitochondrial fusion [GO:0008053]; protein deubiquitination [GO:0016579]; protein K11-linked deubiquitination [GO:0035871]; protein K6-linked deubiquitination [GO:0044313]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000422; GO:0004197; GO:0004843; GO:0005739; GO:0005741; GO:0006511; GO:0008053; GO:0016579; GO:0035871; GO:0044313 3361 XM_029329851.2 9840 9403 7141 7932 8505 Q0VD51 1.8e-50 E3 ubiquitin-protein ligase RNF13 (EC 2.3.2.27) (RING finger protein 13) Bos taurus (Bovine) organelle localization [GO:0051640]; positive regulation of stress-activated protein kinase signaling cascade [GO:0070304]; protein autoubiquitination [GO:0051865]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004842; GO:0005637; GO:0005654; GO:0005765; GO:0005783; GO:0005789; GO:0005829; GO:0006511; GO:0008432; GO:0031902; GO:0046872; GO:0051640; GO:0051865; GO:0061630; GO:0070304 3362 XR_006397264.1 61 43 11 12 57 NA NA NA NA NA NA 3363 XM_044312530.1 1 2 9 29 0 NA NA NA NA NA NA 3364 XM_044324286.1 382 197 235 249 243 Q76IC6 2.28e-53 Palmitoyltransferase ZDHHC23 (EC 2.3.1.225) (NNOS-interacting DHHC domain-containing protein with dendritic mRNA) (Zinc finger DHHC domain-containing protein 23) (DHHC-23) (zDHHC23) Rattus norvegicus (Rat) peptidyl-L-cysteine S-palmitoylation [GO:0018230]; protein localization to plasma membrane [GO:0072659]; protein palmitoylation [GO:0018345]; protein targeting to membrane [GO:0006612] GO:0000139; GO:0005783; GO:0005794; GO:0006612; GO:0018230; GO:0018345; GO:0019706; GO:0072659 3365 XM_029331728.2 7 0 0 0 2 NA NA NA NA NA NA 3366 XM_044323952.1 94 197 134 61 131 Q9CXI3 1.24e-119 DBH-like monooxygenase protein 1 (EC 1.14.17.-) (DBH-related protein) (Monooxygenase X) Mus musculus (Mouse) dopamine catabolic process [GO:0042420]; norepinephrine biosynthetic process [GO:0042421]; octopamine biosynthetic process [GO:0006589] GO:0004500; GO:0005507; GO:0005615; GO:0005789; GO:0006589; GO:0030667; GO:0042420; GO:0042421 3367 XM_044313046.1 17 18 10 29 13 Q9NVH0 1.06e-29 Exonuclease 3'-5' domain-containing protein 2 (EC 3.1.11.1) (3'-5' exoribonuclease EXD2) (EC 3.1.13.-) (Exonuclease 3'-5' domain-like-containing protein 2) Homo sapiens (Human) DNA double-strand break processing [GO:0000729]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; replication fork processing [GO:0031297] GO:0000175; GO:0000287; GO:0000724; GO:0000729; GO:0003676; GO:0005634; GO:0005737; GO:0005739; GO:0005741; GO:0005759; GO:0006302; GO:0008296; GO:0008310; GO:0008408; GO:0008852; GO:0030145; GO:0031297; GO:0042803; GO:0045111; GO:0090305; GO:0090734 3368 XM_044312396.1 5 0 8 0 4 NA NA NA NA NA NA 3369 XM_044307664.1 857 1891 532 712 827 NA NA NA NA NA NA 3370 XM_029340853.2 887 468 306 662 707 NA NA NA NA NA NA 3371 XM_044318329.1 22 21 17 16 41 NA NA NA NA NA NA 3372 XM_044315476.1 62 33 86 0 138 NA NA NA NA NA NA 3373 XM_044323162.1 1 2 10 1 14 NA NA NA NA NA NA 3374 XM_029354686.2 3262 1846 1474 2961 1732 O15992 0 Arginine kinase (AK) (EC 2.7.3.3) Anthopleura japonica (Sea anemone) phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310] GO:0004054; GO:0004111; GO:0005524; GO:0016310; GO:0046314 3375 XR_006397462.1 0 0 3 1 9 NA NA NA NA NA NA 3376 XM_029334327.2 260 159 228 407 16 NA NA NA NA NA NA 3377 XM_029336913.2 50 0 84 226 245 Q765P7 7.58e-59 Protein MTSS 2 (Actin-bundling with BAIAP2 homology protein 1) (ABBA-1) (MTSS1-like protein) Homo sapiens (Human) activation of GTPase activity [GO:0090630]; cell projection assembly [GO:0030031]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; lamellipodium organization [GO:0097581]; membrane organization [GO:0061024]; plasma membrane organization [GO:0007009] GO:0003779; GO:0003785; GO:0005096; GO:0005543; GO:0005546; GO:0007009; GO:0009898; GO:0015629; GO:0030027; GO:0030031; GO:0030864; GO:0031267; GO:0032587; GO:0036120; GO:0061024; GO:0090630; GO:0097581 3378 XM_044328420.1 312 197 186 305 248 O14981 0 TATA-binding protein-associated factor 172 (EC 3.6.4.-) (ATP-dependent helicase BTAF1) (B-TFIID transcription factor-associated 170 kDa subunit) (TAF(II)170) (TBP-associated factor 172) (TAF-172) Homo sapiens (Human) negative regulation of chromatin binding [GO:0035562]; negative regulation of DNA-templated transcription [GO:0045892] GO:0003677; GO:0003712; GO:0004386; GO:0005524; GO:0005654; GO:0008094; GO:0016887; GO:0017025; GO:0035562; GO:0043231; GO:0045892; GO:0140658 3379 XM_044324387.1 28 12 102 139 125 NA NA NA NA NA NA 3380 XM_029346450.2 8 3 5 32 28 NA NA NA NA NA NA 3381 XM_044325711.1 187 0 0 0 317 O60266 0 Adenylate cyclase type 3 (EC 4.6.1.1) (ATP pyrophosphate-lyase 3) (Adenylate cyclase type III) (AC-III) (Adenylate cyclase, olfactive type) (Adenylyl cyclase 3) (AC3) Homo sapiens (Human) acrosome reaction [GO:0007340]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cAMP biosynthetic process [GO:0006171]; cellular response to forskolin [GO:1904322]; flagellated sperm motility [GO:0030317]; intracellular signal transduction [GO:0035556]; olfactory learning [GO:0008355]; sensory perception of smell [GO:0007608]; signal transduction [GO:0007165]; single fertilization [GO:0007338] GO:0004016; GO:0005516; GO:0005524; GO:0005737; GO:0005794; GO:0005886; GO:0005929; GO:0006171; GO:0007165; GO:0007189; GO:0007338; GO:0007340; GO:0007608; GO:0008355; GO:0016020; GO:0030317; GO:0035556; GO:0046872; GO:0060170; GO:1904322 3382 XM_029342067.2 25 13 20 27 7 Q9TST4 4.23e-22 Beta-3 adrenergic receptor (Beta-3 adrenoreceptor) (Beta-3 adrenoceptor) Felis catus (Cat) (Felis silvestris catus) activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; brown fat cell differentiation [GO:0050873]; diet induced thermogenesis [GO:0002024]; heat generation [GO:0031649]; negative regulation of multicellular organism growth [GO:0040015]; norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0002025]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of MAPK cascade [GO:0043410]; response to cold [GO:0009409] GO:0002024; GO:0002025; GO:0004930; GO:0004939; GO:0005886; GO:0007190; GO:0009409; GO:0015052; GO:0031649; GO:0031699; GO:0040015; GO:0042803; GO:0043235; GO:0043410; GO:0050873; GO:0051379; GO:0051380; GO:0071880; GO:0120162 3383 XM_044308715.1 26 41 25 23 58 NA NA NA NA NA NA 3384 XM_029350881.2 0 0 26 0 373 Q6VFT6 3.54e-53 Forkhead box protein L2 Sus scrofa (Pig) anatomical structure morphogenesis [GO:0009653]; apoptotic DNA fragmentation [GO:0006309]; cell differentiation [GO:0030154]; embryonic eye morphogenesis [GO:0048048]; extraocular skeletal muscle development [GO:0002074]; female somatic sex determination [GO:0019101]; granulosa cell differentiation [GO:0060014]; ovarian follicle development [GO:0001541]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0001541; GO:0002074; GO:0003677; GO:0003700; GO:0005634; GO:0006309; GO:0006357; GO:0009653; GO:0019101; GO:0030154; GO:0043028; GO:0043065; GO:0043280; GO:0045893; GO:0045944; GO:0048048; GO:0060014 3385 XM_029340129.2 1347 679 697 977 881 Q6ZQ89 0 E3 ubiquitin-protein ligase MARCHF6 (EC 2.3.2.27) (Membrane-associated RING finger protein 6) (Membrane-associated RING-CH protein VI) (MARCH-VI) (RING-type E3 ubiquitin transferase MARCHF6) Mus musculus (Mouse) proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination [GO:0016567]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0004842; GO:0005783; GO:0005789; GO:0008270; GO:0010498; GO:0016020; GO:0016567; GO:0019899; GO:0030433; GO:0031624; GO:0043161; GO:0061630; GO:0070936; GO:1990381 3386 XM_029340129.2 1347 679 697 977 881 Q6ZQ89 1.18e-83 E3 ubiquitin-protein ligase MARCHF6 (EC 2.3.2.27) (Membrane-associated RING finger protein 6) (Membrane-associated RING-CH protein VI) (MARCH-VI) (RING-type E3 ubiquitin transferase MARCHF6) Mus musculus (Mouse) proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination [GO:0016567]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0004842; GO:0005783; GO:0005789; GO:0008270; GO:0010498; GO:0016020; GO:0016567; GO:0019899; GO:0030433; GO:0031624; GO:0043161; GO:0061630; GO:0070936; GO:1990381 3387 XM_029337291.2 1179 2263 1659 2279 1877 NA NA NA NA NA NA 3388 XM_029334646.2 373 105 136 190 101 Q17094 1.32e-23 Rhodopsin Alloteuthis subulata (Squid) (Loligo subulata) phototransduction [GO:0007602]; visual perception [GO:0007601] GO:0004930; GO:0005886; GO:0007601; GO:0007602; GO:0009881; GO:0016020; GO:0016918 3389 XM_029348423.2 1230 969 518 746 815 Q3ZBF3 5.92e-56 39S ribosomal protein L38, mitochondrial (L38mt) (MRP-L38) Bos taurus (Bovine) NA GO:0005743; GO:0005762 3390 XM_029358146.2 212 0 58 64 435 NA NA NA NA NA NA 3391 XM_044314650.1 0 6 0 9 0 NA NA NA NA NA NA 3392 XM_029348758.2 21 52 31 19 42 NA NA NA NA NA NA 3393 XM_044313928.1 1 35 0 11 8 NA NA NA NA NA NA 3394 XM_029331277.2 0 474 341 1054 518 Q14192 1.14e-70 Four and a half LIM domains protein 2 (FHL-2) (LIM domain protein DRAL) (Skeletal muscle LIM-protein 3) (SLIM-3) Homo sapiens (Human) atrial cardiac muscle cell development [GO:0055014]; heart trabecula formation [GO:0060347]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of transcription by RNA polymerase II [GO:0000122]; osteoblast differentiation [GO:0001649]; response to hormone [GO:0009725]; ventricular cardiac muscle cell development [GO:0055015] GO:0000122; GO:0001649; GO:0003712; GO:0003714; GO:0005634; GO:0005654; GO:0005925; GO:0008134; GO:0009725; GO:0030018; GO:0042802; GO:0043066; GO:0043425; GO:0046872; GO:0055014; GO:0055015; GO:0060347; GO:0070885 3395 XM_029331277.2 0 474 341 1054 518 Q14192 3.64e-30 Four and a half LIM domains protein 2 (FHL-2) (LIM domain protein DRAL) (Skeletal muscle LIM-protein 3) (SLIM-3) Homo sapiens (Human) atrial cardiac muscle cell development [GO:0055014]; heart trabecula formation [GO:0060347]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of transcription by RNA polymerase II [GO:0000122]; osteoblast differentiation [GO:0001649]; response to hormone [GO:0009725]; ventricular cardiac muscle cell development [GO:0055015] GO:0000122; GO:0001649; GO:0003712; GO:0003714; GO:0005634; GO:0005654; GO:0005925; GO:0008134; GO:0009725; GO:0030018; GO:0042802; GO:0043066; GO:0043425; GO:0046872; GO:0055014; GO:0055015; GO:0060347; GO:0070885 3396 XM_029331277.2 0 474 341 1054 518 Q14192 3.46e-22 Four and a half LIM domains protein 2 (FHL-2) (LIM domain protein DRAL) (Skeletal muscle LIM-protein 3) (SLIM-3) Homo sapiens (Human) atrial cardiac muscle cell development [GO:0055014]; heart trabecula formation [GO:0060347]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of transcription by RNA polymerase II [GO:0000122]; osteoblast differentiation [GO:0001649]; response to hormone [GO:0009725]; ventricular cardiac muscle cell development [GO:0055015] GO:0000122; GO:0001649; GO:0003712; GO:0003714; GO:0005634; GO:0005654; GO:0005925; GO:0008134; GO:0009725; GO:0030018; GO:0042802; GO:0043066; GO:0043425; GO:0046872; GO:0055014; GO:0055015; GO:0060347; GO:0070885 3397 XR_006392881.1 41 2 25 5 151 NA NA NA NA NA NA 3398 XM_029330756.2 14 2 7 9 23 NA NA NA NA NA NA 3399 XM_044319380.1 163 187 221 116 158 P84239 8.65e-90 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 3400 XR_006391648.1 33 16 63 52 85 NA NA NA NA NA NA 3401 XM_044324548.1 184 54 200 236 451 H1AFJ5 3.12e-39 Amiloride-sensitive sodium channel subunit alpha (Alpha-NaCH) (Epithelial Na(+) channel subunit alpha) (Alpha-ENaC) (Nonvoltage-gated sodium channel 1 subunit alpha) (SCNEA) Neoceratodus forsteri (Australian lungfish) (Ceratodus forsteri) sodium ion transmembrane transport [GO:0035725] GO:0001669; GO:0005737; GO:0015280; GO:0016324; GO:0031514; GO:0034706; GO:0035725 3402 XR_006393762.1 0 56 3 0 3 NA NA NA NA NA NA 3403 XM_029357558.2 633 296 475 424 757 Q91YE6 0 Importin-9 (Imp9) (Importin-9a) (Imp9a) (Importin-9b) (Imp9b) (Ran-binding protein 9) (RanBP9) Mus musculus (Mouse) proteasome localization [GO:0031144]; protein import into nucleus [GO:0006606]; protein stabilization [GO:0050821]; ribosome biogenesis [GO:0042254] GO:0005635; GO:0005737; GO:0005829; GO:0006606; GO:0031144; GO:0031267; GO:0042254; GO:0042393; GO:0050821; GO:0061608; GO:0140713 3404 XM_029343936.2 824 423 172 1287 407 NA NA NA NA NA NA 3405 XM_044308741.1 176 67 127 366 74 NA NA NA NA NA NA 3406 XM_029338092.2 17 0 5 27 31 P30975 5.6e-30 Tachykinin-like peptides receptor 99D (Tachykinin-like receptor at 99D) (dTKR) Drosophila melanogaster (Fruit fly) detection of chemical stimulus involved in sensory perception of smell [GO:0050911]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; neuropeptide signaling pathway [GO:0007218]; olfactory behavior [GO:0042048]; positive regulation of sensory perception of pain [GO:1904058]; tachykinin receptor signaling pathway [GO:0007217] GO:0004995; GO:0005886; GO:0007186; GO:0007217; GO:0007218; GO:0008188; GO:0016020; GO:0042048; GO:0050805; GO:0050911; GO:1904058 3407 XM_044328419.1 27 128 15 0 73 NA NA NA NA NA NA 3408 XM_029327550.2 40 59 21 42 8 NA NA NA NA NA NA 3409 XM_044307262.1 71 86 376 527 7 NA NA NA NA NA NA 3410 XM_029356855.2 75 1 13 15 53 NA NA NA NA NA NA 3411 XM_044320453.1 1785 1343 967 1711 1922 O95487 0 Protein transport protein Sec24B (SEC24-related protein B) Homo sapiens (Human) aorta morphogenesis [GO:0035909]; auditory receptor cell stereocilium organization [GO:0060088]; cochlear nucleus development [GO:0021747]; COPII-coated vesicle cargo loading [GO:0090110]; coronary artery morphogenesis [GO:0060982]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; lung lobe morphogenesis [GO:0060463]; neural tube closure [GO:0001843]; outflow tract morphogenesis [GO:0003151]; pulmonary artery morphogenesis [GO:0061156]; regulation of cargo loading into COPII-coated vesicle [GO:1901301]; regulation of establishment of planar polarity involved in neural tube closure [GO:0090178] GO:0000149; GO:0001843; GO:0003151; GO:0005789; GO:0005829; GO:0006886; GO:0006888; GO:0008270; GO:0012507; GO:0021747; GO:0030127; GO:0035909; GO:0060088; GO:0060463; GO:0060982; GO:0061156; GO:0070971; GO:0090110; GO:0090178; GO:1901301 3412 XM_029323991.2 47 55 0 189 101 D3Z7P3 0 Glutaminase kidney isoform, mitochondrial (GLS) (EC 3.5.1.2) [Cleaved into: Glutaminase kidney isoform, mitochondrial 68 kDa chain; Glutaminase kidney isoform, mitochondrial 65 kDa chain] Mus musculus (Mouse) cellular glutamate homeostasis [GO:0090461]; chemical synaptic transmission [GO:0007268]; glutamate biosynthetic process [GO:0006537]; glutamine catabolic process [GO:0006543]; protein homotetramerization [GO:0051289]; regulation of respiratory gaseous exchange by nervous system process [GO:0002087]; suckling behavior [GO:0001967] GO:0001967; GO:0002087; GO:0004359; GO:0005739; GO:0005759; GO:0005829; GO:0006537; GO:0006543; GO:0007268; GO:0042802; GO:0045202; GO:0051289; GO:0090461 3413 XM_044312703.1 0 9 0 0 2 NA NA NA NA NA NA 3414 XM_029330485.2 129 23 90 103 0 NA NA NA NA NA NA 3415 XM_029355526.2 1301 970 1021 1401 1019 NA NA NA NA NA NA 3416 XR_006392639.1 14 0 12 2 48 Q96AY4 1.12e-51 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3417 XR_006392639.1 14 0 12 2 48 Q96AY4 1.99e-47 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3418 XR_006392639.1 14 0 12 2 48 Q96AY4 1.99e-47 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3419 XR_006392639.1 14 0 12 2 48 Q96AY4 1.07e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3420 XR_006392639.1 14 0 12 2 48 Q96AY4 8.83e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3421 XR_006392639.1 14 0 12 2 48 Q96AY4 8.83e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3422 XR_006392639.1 14 0 12 2 48 Q96AY4 8.83e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3423 XR_006392639.1 14 0 12 2 48 Q96AY4 8.83e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3424 XR_006392639.1 14 0 12 2 48 Q96AY4 5.13e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3425 XR_006392639.1 14 0 12 2 48 Q96AY4 5.13e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3426 XR_006392639.1 14 0 12 2 48 Q96AY4 3.6e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3427 XR_006392639.1 14 0 12 2 48 Q96AY4 3.6e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3428 XR_006392639.1 14 0 12 2 48 Q96AY4 3.6e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3429 XR_006392639.1 14 0 12 2 48 Q96AY4 3.6e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3430 XR_006392639.1 14 0 12 2 48 Q96AY4 6.35e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3431 XR_006392639.1 14 0 12 2 48 Q96AY4 3.55e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3432 XR_006392639.1 14 0 12 2 48 Q96AY4 3.55e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3433 XR_006392639.1 14 0 12 2 48 Q96AY4 3.55e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3434 XR_006392639.1 14 0 12 2 48 Q96AY4 3.55e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3435 XR_006392639.1 14 0 12 2 48 Q96AY4 2.69e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3436 XR_006392639.1 14 0 12 2 48 Q96AY4 2.69e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3437 XR_006392639.1 14 0 12 2 48 Q96AY4 4.23e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3438 XR_006392639.1 14 0 12 2 48 Q96AY4 5.61e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3439 XR_006392639.1 14 0 12 2 48 Q96AY4 5.61e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3440 XR_006392639.1 14 0 12 2 48 Q96AY4 5.61e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3441 XR_006392639.1 14 0 12 2 48 Q96AY4 6.62e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3442 XR_006392639.1 14 0 12 2 48 Q96AY4 6.62e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3443 XR_006392639.1 14 0 12 2 48 Q96AY4 6.62e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3444 XR_006392639.1 14 0 12 2 48 Q96AY4 1.43e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3445 XR_006392639.1 14 0 12 2 48 Q96AY4 1.43e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3446 XR_006392639.1 14 0 12 2 48 Q96AY4 1.43e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3447 XR_006392639.1 14 0 12 2 48 Q96AY4 3.94e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3448 XR_006392639.1 14 0 12 2 48 Q96AY4 1.18e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3449 XR_006392639.1 14 0 12 2 48 Q96AY4 1.18e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3450 XR_006392639.1 14 0 12 2 48 Q96AY4 1.18e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3451 XR_006392639.1 14 0 12 2 48 Q96AY4 1.32e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3452 XR_006392639.1 14 0 12 2 48 Q96AY4 1.32e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3453 XR_006392639.1 14 0 12 2 48 Q96AY4 2.87e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3454 XM_044324916.1 0 0 135 7 49 Q9UQ26 2.73e-63 Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2) (Rab-3-interacting protein 3) Homo sapiens (Human) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-ion regulated exocytosis [GO:0017156]; cell differentiation [GO:0030154]; insulin secretion [GO:0030073]; intracellular protein transport [GO:0006886]; positive regulation of dendrite extension [GO:1903861]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of synaptic transmission [GO:0050806]; regulation of exocytosis [GO:0017157]; regulation of membrane potential [GO:0042391]; regulation of synaptic plasticity [GO:0048167]; spontaneous neurotransmitter secretion [GO:0061669] GO:0006886; GO:0007188; GO:0017156; GO:0017157; GO:0030073; GO:0030154; GO:0031267; GO:0042391; GO:0042734; GO:0042995; GO:0044325; GO:0046872; GO:0048167; GO:0048786; GO:0048788; GO:0048791; GO:0050806; GO:0061669; GO:0070062; GO:0097151; GO:1903861; GO:2000463 3455 XM_044324916.1 0 0 135 7 49 Q9UQ26 1.44e-30 Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2) (Rab-3-interacting protein 3) Homo sapiens (Human) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-ion regulated exocytosis [GO:0017156]; cell differentiation [GO:0030154]; insulin secretion [GO:0030073]; intracellular protein transport [GO:0006886]; positive regulation of dendrite extension [GO:1903861]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of synaptic transmission [GO:0050806]; regulation of exocytosis [GO:0017157]; regulation of membrane potential [GO:0042391]; regulation of synaptic plasticity [GO:0048167]; spontaneous neurotransmitter secretion [GO:0061669] GO:0006886; GO:0007188; GO:0017156; GO:0017157; GO:0030073; GO:0030154; GO:0031267; GO:0042391; GO:0042734; GO:0042995; GO:0044325; GO:0046872; GO:0048167; GO:0048786; GO:0048788; GO:0048791; GO:0050806; GO:0061669; GO:0070062; GO:0097151; GO:1903861; GO:2000463 3456 XR_006392664.1 2 12 3 9 3 NA NA NA NA NA NA 3457 XR_006392002.1 3 0 0 0 101 NA NA NA NA NA NA 3458 XM_029348589.2 710 326 260 448 294 A8WH34 4.69e-23 Glycosylated lysosomal membrane protein B (Lysosomal protein NCU-G1-B) Xenopus laevis (African clawed frog) protein localization to lysosome [GO:0061462]; protein stabilization [GO:0050821] GO:0005764; GO:0005765; GO:0016020; GO:0050821; GO:0061462 3459 XM_044328606.1 0 29 0 0 0 NA NA NA NA NA NA 3460 XM_029329499.2 228 149 64 196 73 NA NA NA NA NA NA 3461 XM_044326006.1 66 0 0 17 0 NA NA NA NA NA NA 3462 XM_044308012.1 392 283 240 162 231 NA NA NA NA NA NA 3463 XM_044318051.1 880 740 501 999 732 Q8VHI7 3.59e-159 Dynein regulatory complex subunit 2 (Coiled-coil domain-containing protein 65) (Testis development protein NYD-SP28) Mus musculus (Mouse) axonemal dynein complex assembly [GO:0070286]; cilium assembly [GO:0060271]; cilium-dependent cell motility [GO:0060285]; regulation of cilium movement [GO:0003352] GO:0003352; GO:0005858; GO:0005930; GO:0031514; GO:0036064; GO:0060271; GO:0060285; GO:0070286 3464 XR_006392131.1 20 38 84 78 109 NA NA NA NA NA NA 3465 XM_044329319.1 0 6 14 6 0 NA NA NA NA NA NA 3466 XM_044325421.1 36 0 46 0 923 NA NA NA NA NA NA 3467 XM_044323522.1 319 254 452 692 574 Q5ZKI4 0 Coiled-coil domain-containing protein 93 Gallus gallus (Chicken) Golgi to plasma membrane transport [GO:0006893]; protein transport [GO:0015031] GO:0005769; GO:0006893; GO:0015031 3468 XM_029356142.2 162 99 67 163 71 P79401 2.7e-103 Cytochrome P450 3A29 (EC 1.14.14.1) (CYPIIIA29) Sus scrofa (Pig) cellular response to type I interferon [GO:0071357]; oxidative demethylation [GO:0070989]; steroid metabolic process [GO:0008202] GO:0004497; GO:0005506; GO:0005789; GO:0008202; GO:0008395; GO:0020037; GO:0050649; GO:0070330; GO:0070989; GO:0071357 3469 XM_044320855.1 54 4 25 68 85 NA NA NA NA NA NA 3470 XM_044325977.1 65 0 11 72 192 NA NA NA NA NA NA 3471 XM_044310274.1 7 7 10 0 19 Q96AY4 5.18e-76 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3472 XM_044310274.1 7 7 10 0 19 Q96AY4 4.1e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3473 XM_044310274.1 7 7 10 0 19 Q96AY4 1.46e-71 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3474 XM_044310274.1 7 7 10 0 19 Q96AY4 9.22e-69 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3475 XM_044310274.1 7 7 10 0 19 Q96AY4 2.62e-68 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3476 XM_044310274.1 7 7 10 0 19 Q96AY4 1.98e-65 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3477 XM_029339938.2 0 0 18 105 2 Q09081 3.81e-88 Potassium voltage-gated channel subfamily A member 2 (KC22) (Voltage-gated potassium channel subunit Kv1.2) Oryctolagus cuniculus (Rabbit) neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233] GO:0005249; GO:0005251; GO:0005789; GO:0005886; GO:0008076; GO:0014059; GO:0019228; GO:0019233; GO:0021633; GO:0030027; GO:0030424; GO:0030425; GO:0031258; GO:0032809; GO:0033010; GO:0034765; GO:0042734; GO:0043194; GO:0043204; GO:0043679; GO:0044224; GO:0045188; GO:0051260; GO:0071805 3478 XM_029324918.2 12 0 3 0 98 NA NA NA NA NA NA 3479 XR_006394749.1 0 4 9 0 13 NA NA NA NA NA NA 3480 XM_029332941.2 52 67 42 94 138 NA NA NA NA NA NA 3481 XM_029329453.2 11 14 61 85 0 NA NA NA NA NA NA 3482 XM_044327486.1 2 2 12 16 14 NA NA NA NA NA NA 3483 XM_044328069.1 2 19 22 9 83 NA NA NA NA NA NA 3484 XM_029343292.2 113 201 133 180 135 NA NA NA NA NA NA 3485 XM_044315570.1 37 0 3 11 0 NA NA NA NA NA NA 3486 XM_029349850.2 4875 3495 2862 5767 5065 NA NA NA NA NA NA 3487 XM_044325887.1 630 423 241 401 416 P54001 1.03e-121 Prolyl 4-hydroxylase subunit alpha-1 (4-PH alpha-1) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1) Rattus norvegicus (Rat) collagen fibril organization [GO:0030199]; peptidyl-proline hydroxylation [GO:0019511]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401] GO:0004656; GO:0005506; GO:0005783; GO:0005788; GO:0016222; GO:0018401; GO:0019511; GO:0030199; GO:0031418; GO:0042802 3488 XM_044312567.1 342 163 517 84 1272 NA NA NA NA NA NA 3489 XM_044320574.1 93 84 0 56 105 NA NA NA NA NA NA 3490 XM_029356036.2 4129 3729 1901 4002 1938 Q08CX1 1.91e-66 Ras and EF-hand domain-containing protein Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0003924; GO:0005509; GO:0005525; GO:0048471 3491 XM_029356036.2 4129 3729 1901 4002 1938 Q08CX1 7.96e-29 Ras and EF-hand domain-containing protein Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0003924; GO:0005509; GO:0005525; GO:0048471 3492 XM_029348649.2 96 48 39 76 90 NA NA NA NA NA NA 3493 XM_029346030.2 470 189 186 266 261 O75179 4.21e-90 Ankyrin repeat domain-containing protein 17 (Gene trap ankyrin repeat protein) (Serologically defined breast cancer antigen NY-BR-16) Homo sapiens (Human) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0016020; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 3494 XM_029346030.2 470 189 186 266 261 O75179 2.02e-84 Ankyrin repeat domain-containing protein 17 (Gene trap ankyrin repeat protein) (Serologically defined breast cancer antigen NY-BR-16) Homo sapiens (Human) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0016020; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 3495 XM_029346030.2 470 189 186 266 261 O75179 2.89e-69 Ankyrin repeat domain-containing protein 17 (Gene trap ankyrin repeat protein) (Serologically defined breast cancer antigen NY-BR-16) Homo sapiens (Human) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0016020; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 3496 XM_029346030.2 470 189 186 266 261 O75179 1.71e-64 Ankyrin repeat domain-containing protein 17 (Gene trap ankyrin repeat protein) (Serologically defined breast cancer antigen NY-BR-16) Homo sapiens (Human) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0016020; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 3497 XM_029346030.2 470 189 186 266 261 O75179 3e-62 Ankyrin repeat domain-containing protein 17 (Gene trap ankyrin repeat protein) (Serologically defined breast cancer antigen NY-BR-16) Homo sapiens (Human) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0016020; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 3498 XM_029346030.2 470 189 186 266 261 O75179 2.79e-58 Ankyrin repeat domain-containing protein 17 (Gene trap ankyrin repeat protein) (Serologically defined breast cancer antigen NY-BR-16) Homo sapiens (Human) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0016020; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 3499 XM_029346030.2 470 189 186 266 261 O75179 1.17e-35 Ankyrin repeat domain-containing protein 17 (Gene trap ankyrin repeat protein) (Serologically defined breast cancer antigen NY-BR-16) Homo sapiens (Human) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0016020; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 3500 XM_029330762.2 19 25 16 13 29 NA NA NA NA NA NA 3501 XM_029337058.2 46 0 0 39 27 Q8IVH2 3.52e-74 Forkhead box protein P4 (Fork head-related protein-like A) Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000785; GO:0000978; GO:0000981; GO:0001227; GO:0005634; GO:0006357; GO:0046872 3502 XR_006392888.1 41 2 25 5 151 NA NA NA NA NA NA 3503 XM_029335657.2 3819 3597 1972 4532 1311 NA NA NA NA NA NA 3504 XM_029338178.2 478 468 220 258 703 Q7TS68 9.17e-139 tRNA (cytosine(72)-C(5))-methyltransferase NSUN6 (EC 2.1.1.-) (NOL1/NOP2/Sun domain family member 6) Mus musculus (Mouse) RNA methylation [GO:0001510]; tRNA C5-cytosine methylation [GO:0002946]; tRNA methylation [GO:0030488] GO:0000049; GO:0001510; GO:0002946; GO:0005654; GO:0005737; GO:0016428; GO:0030488 3505 XM_029346680.2 178 141 118 171 263 Q6DD45 5.78e-44 Zinc finger CCHC domain-containing protein 8 (TRAMP-like complex RNA-binding factor ZCCHC8) Xenopus laevis (African clawed frog) ncRNA processing [GO:0034470] GO:0003676; GO:0005654; GO:0008270; GO:0034470 3506 XR_006393175.1 0 0 13 0 45 P07207 5.97e-134 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3507 XR_006393175.1 0 0 13 0 45 P07207 5.97e-134 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3508 XR_006393175.1 0 0 13 0 45 P07207 5.97e-134 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3509 XR_006393175.1 0 0 13 0 45 P07207 5.97e-134 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3510 XR_006393175.1 0 0 13 0 45 P07207 5.97e-134 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3511 XR_006393175.1 0 0 13 0 45 P07207 9.33e-129 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3512 XR_006393175.1 0 0 13 0 45 P07207 9.33e-129 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3513 XR_006393175.1 0 0 13 0 45 P07207 9.33e-129 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3514 XR_006393175.1 0 0 13 0 45 P07207 9.33e-129 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3515 XR_006393175.1 0 0 13 0 45 P07207 9.33e-129 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3516 XR_006393175.1 0 0 13 0 45 P07207 1.09e-103 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3517 XR_006393175.1 0 0 13 0 45 P07207 1.09e-103 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3518 XR_006393175.1 0 0 13 0 45 P07207 1.09e-103 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3519 XR_006393175.1 0 0 13 0 45 P07207 4.32e-97 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3520 XR_006393175.1 0 0 13 0 45 P07207 4.32e-97 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3521 XR_006393175.1 0 0 13 0 45 P07207 4.32e-97 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3522 XR_006393175.1 0 0 13 0 45 P07207 6.77e-88 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3523 XR_006393175.1 0 0 13 0 45 P07207 6.77e-88 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3524 XR_006393175.1 0 0 13 0 45 P07207 6.77e-88 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3525 XR_006393175.1 0 0 13 0 45 P07207 6.77e-88 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3526 XR_006393175.1 0 0 13 0 45 P07207 2.56e-85 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3527 XR_006393175.1 0 0 13 0 45 P07207 2.56e-85 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3528 XR_006393175.1 0 0 13 0 45 P07207 1.45e-75 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3529 XR_006393175.1 0 0 13 0 45 P07207 1.45e-75 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3530 XR_006393175.1 0 0 13 0 45 P07207 1.45e-75 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3531 XR_006393175.1 0 0 13 0 45 P07207 1.91e-73 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3532 XR_006393175.1 0 0 13 0 45 P07207 8.42e-70 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3533 XR_006393175.1 0 0 13 0 45 P07207 1.13e-68 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3534 XR_006393175.1 0 0 13 0 45 P07207 3.83e-55 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3535 XR_006393175.1 0 0 13 0 45 P07207 3.83e-55 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3536 XR_006393175.1 0 0 13 0 45 P07207 1.05e-54 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3537 XR_006393175.1 0 0 13 0 45 P07207 1.05e-54 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3538 XR_006393175.1 0 0 13 0 45 P07207 1.05e-54 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3539 XR_006393175.1 0 0 13 0 45 P07207 7.56e-53 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3540 XR_006393175.1 0 0 13 0 45 P07207 7.56e-53 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3541 XR_006393175.1 0 0 13 0 45 P07207 2.71e-52 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3542 XR_006393175.1 0 0 13 0 45 P07207 2.71e-52 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3543 XR_006393175.1 0 0 13 0 45 P07207 2.71e-52 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3544 XR_006393175.1 0 0 13 0 45 P07207 1.25e-38 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3545 XR_006393175.1 0 0 13 0 45 P07207 7.85e-37 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3546 XR_006393175.1 0 0 13 0 45 P07207 6.05e-36 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3547 XR_006393175.1 0 0 13 0 45 P07207 6.05e-36 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3548 XR_006393175.1 0 0 13 0 45 P07207 3.91e-33 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3549 XR_006393175.1 0 0 13 0 45 P07207 3.02e-29 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3550 XR_006393175.1 0 0 13 0 45 P07207 3.02e-29 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3551 XR_006393175.1 0 0 13 0 45 P07207 4.36e-25 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3552 XR_006393175.1 0 0 13 0 45 P07207 4.36e-25 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3553 XR_006393175.1 0 0 13 0 45 P07207 4.98e-24 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3554 XR_006393175.1 0 0 13 0 45 P07207 4.98e-24 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3555 XR_006393175.1 0 0 13 0 45 P07207 1.62e-23 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3556 XR_006393175.1 0 0 13 0 45 P07207 3.09e-23 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3557 XR_006393175.1 0 0 13 0 45 P07207 3.09e-23 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3558 XR_006393175.1 0 0 13 0 45 P07207 7.01e-23 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3559 XR_006393175.1 0 0 13 0 45 P07207 8.5e-23 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3560 XR_006393175.1 0 0 13 0 45 P07207 3.02e-21 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 3561 XM_029336036.2 727 1372 576 861 652 Q5RCE6 3.15e-25 Ribosomal L1 domain-containing protein 1 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) regulation of apoptotic process [GO:0042981]; regulation of cellular senescence [GO:2000772] GO:0005730; GO:0042981; GO:2000772 3562 XM_029340488.2 133 12 44 98 163 NA NA NA NA NA NA 3563 XM_029323408.2 354 420 249 551 279 NA NA NA NA NA NA 3564 XM_044309783.1 603 377 672 332 1455 NA NA NA NA NA NA 3565 XM_044321323.1 26 8 42 11 70 B8V7S0 1.91e-25 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 3566 XM_044323078.1 0 0 0 31 0 NA NA NA NA NA NA 3567 XM_029324736.2 9 0 17 25 16 Q68F72 5.14e-73 Solute carrier family 15 member 4 Xenopus laevis (African clawed frog) dipeptide import across plasma membrane [GO:0140206]; innate immune response [GO:0045087]; mast cell homeostasis [GO:0033023]; peptidoglycan transport [GO:0015835]; positive regulation of innate immune response [GO:0045089]; positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [GO:0070430]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of toll-like receptor 7 signaling pathway [GO:0034157]; positive regulation of toll-like receptor 8 signaling pathway [GO:0034161]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; protein transport [GO:0015031]; regulation of isotype switching to IgG isotypes [GO:0048302]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424] GO:0005290; GO:0005765; GO:0015031; GO:0015333; GO:0015647; GO:0015835; GO:0031901; GO:0033023; GO:0034157; GO:0034161; GO:0034165; GO:0036020; GO:0045087; GO:0045089; GO:0048302; GO:0070424; GO:0070430; GO:0070434; GO:0071916; GO:0140206 3568 XM_029346414.2 4 5 7 7 4 NA NA NA NA NA NA 3569 XM_044310656.1 266 227 106 408 98 NA NA NA NA NA NA 3570 XR_006395791.1 0 3 22 0 17 NA NA NA NA NA NA 3571 XM_044313666.1 17 24 13 20 0 NA NA NA NA NA NA 3572 XR_006394223.1 117 73 2 0 43 NA NA NA NA NA NA 3573 XM_044326788.1 31 33 7 29 2 Q8HYZ1 3.34e-98 Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2) Mustela putorius furo (European domestic ferret) (Mustela furo) cardiac muscle cell action potential [GO:0086001]; cellular response to hypoxia [GO:0071456]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005250; GO:0005886; GO:0005901; GO:0008076; GO:0030315; GO:0032809; GO:0034765; GO:0042383; GO:0043197; GO:0043204; GO:0044853; GO:0045211; GO:0046872; GO:0051260; GO:0070161; GO:0071456; GO:0071805; GO:0086001 3574 XM_029347096.2 15 14 0 32 30 NA NA NA NA NA NA 3575 XM_029334526.2 224 52 226 58 371 NA NA NA NA NA NA 3576 XM_029348353.2 7461 6201 5785 9047 7799 NA NA NA NA NA NA 3577 XM_044310221.1 6 0 0 3 0 NA NA NA NA NA NA 3578 XM_029350695.2 1230 939 591 627 578 Q0P651 4.86e-102 Protein ABHD18 (Alpha/beta hydrolase domain-containing protein 18) (Abhydrolase domain-containing protein 18) Homo sapiens (Human) NA GO:0005576 3579 XM_044310753.1 20 628 374 177 736 NA NA NA NA NA NA 3580 XM_029328825.2 281 113 239 192 270 Q11126 7.78e-43 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3 (EC 2.4.1.65) (4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase) (EC 2.4.1.152) (Alpha-3-fucosyltransferase FUT3) (EC 2.4.1.-) (Blood group Lewis alpha-4-fucosyltransferase) (Lewis FT) (FUTB) (Fucosyltransferase 3) (Fucosyltransferase III) (FucT-III) Bos taurus (Bovine) fucosylation [GO:0036065]; lipid metabolic process [GO:0006629]; oligosaccharide metabolic process [GO:0009311]; positive regulation of cell-cell adhesion [GO:0022409]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127] GO:0006487; GO:0006493; GO:0006629; GO:0009311; GO:0017060; GO:0017083; GO:0022409; GO:0030334; GO:0032580; GO:0036065; GO:0042127; GO:0046920 3581 XM_029326489.2 26 0 10 5 2 Q1LZE9 6.62e-31 Serine protease 23 (EC 3.4.21.-) Bos taurus (Bovine) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0005634; GO:0006508 3582 XM_029334548.2 183 90 127 161 254 NA NA NA NA NA NA 3583 XM_044319313.1 60 0 0 16 0 Q9GV16 0 Endoglycoceramidase (EGCase) (EC 3.2.1.123) (Glycosphingolipid-specific enzyme) (GSL-specific enzyme) Cyanea nozakii (Jellyfish) carbohydrate derivative catabolic process [GO:1901136]; cellulose catabolic process [GO:0030245]; lipid catabolic process [GO:0016042] GO:0005576; GO:0016042; GO:0030245; GO:0042151; GO:0047876; GO:1901136 3584 XM_029330618.2 2 5 20 17 36 NA NA NA NA NA NA 3585 XM_044323311.1 52 0 34 26 129 Q9HAR2 5.62e-75 Adhesion G protein-coupled receptor L3 (Calcium-independent alpha-latrotoxin receptor 3) (CIRL-3) (Latrophilin-3) (Lectomedin-3) Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; brain development [GO:0007420]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; G protein-coupled receptor signaling pathway [GO:0007186]; neuron migration [GO:0001764]; synapse assembly [GO:0007416] GO:0001764; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007166; GO:0007186; GO:0007189; GO:0007416; GO:0007420; GO:0016020; GO:0030246; GO:0030424; GO:0098742; GO:0098978 3586 XM_044315648.1 174 106 0 167 179 NA NA NA NA NA NA 3587 XM_029337173.2 4573 9276 3284 11549 7986 NA NA NA NA NA NA 3588 XM_044314978.1 370 166 164 276 368 Q96LW4 3.51e-111 DNA-directed primase/polymerase protein (hPrimpol1) (EC 2.7.7.-) (Coiled-coil domain-containing protein 111) Homo sapiens (Human) error-prone translesion synthesis [GO:0042276]; mitochondrial DNA repair [GO:0043504]; mitochondrial DNA replication [GO:0006264]; R-loop processing [GO:0062176]; replication fork processing [GO:0031297]; response to UV [GO:0009411]; translesion synthesis [GO:0019985] GO:0000428; GO:0003682; GO:0003887; GO:0003896; GO:0005634; GO:0005657; GO:0005759; GO:0006264; GO:0008270; GO:0009411; GO:0019985; GO:0030145; GO:0031297; GO:0042276; GO:0043504; GO:0062176 3589 XM_029342446.2 45 27 25 48 66 NA NA NA NA NA NA 3590 XM_029336762.2 621 434 478 599 668 D3Z5L6 3.86e-54 MFS-type transporter SLC18B1 (Solute carrier family 18 member B1) (Vesicular polyamine transporter) (VPAT) Mus musculus (Mouse) serotonin transport [GO:0006837]; serotonin uptake [GO:0051610]; spermidine transport [GO:0015848]; spermine transport [GO:0000296] GO:0000296; GO:0006837; GO:0015311; GO:0015312; GO:0015848; GO:0022857; GO:0030667; GO:0030672; GO:0051610 3591 XM_029344790.2 567 448 240 443 548 Q704E8 0 Iron-sulfur clusters transporter ABCB7, mitochondrial (ATP-binding cassette sub-family B member 7, mitochondrial) (ATP-binding cassette transporter 7) (ABC transporter 7 protein) Rattus norvegicus (Rat) cellular iron ion homeostasis [GO:0006879]; iron ion homeostasis [GO:0055072]; iron ion transmembrane transport [GO:0034755]; iron-sulfur cluster assembly [GO:0016226]; iron-sulfur cluster export from the mitochondrion [GO:0140466]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; positive regulation of heme biosynthetic process [GO:0070455]; positive regulation of iron-sulfur cluster assembly [GO:1903331]; transmembrane transport [GO:0055085] GO:0005524; GO:0005739; GO:0005743; GO:0006879; GO:0016020; GO:0016226; GO:0016887; GO:0034755; GO:0042626; GO:0042803; GO:0055072; GO:0055085; GO:0070455; GO:0140466; GO:0140481; GO:1903331; GO:1903427 3592 XR_006394150.1 4 0 11 0 4 NA NA NA NA NA NA 3593 XM_029350321.2 0 0 53 0 101 NA NA NA NA NA NA 3594 XR_006392280.1 257 94 81 113 253 NA NA NA NA NA NA 3595 XR_006395545.1 3 8 4 2 11 NA NA NA NA NA NA 3596 XM_029358209.2 0 0 0 8 0 NA NA NA NA NA NA 3597 XM_029356321.2 5545 4980 3656 5898 5896 Q90687 0 Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (SH-PTP2) (cSH-PTP2) Gallus gallus (Chicken) cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to organic substance [GO:0071310]; negative regulation of chondrocyte differentiation [GO:0032331]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of ossification [GO:0045778]; protein dephosphorylation [GO:0006470] GO:0004725; GO:0004726; GO:0005634; GO:0005737; GO:0006470; GO:0030971; GO:0032331; GO:0045778; GO:0050839; GO:0070374; GO:0071310; GO:0071364 3598 XM_044307062.1 0 0 0 29 0 NA NA NA NA NA NA 3599 XM_029356668.2 5437 4589 3298 7221 5738 Q501Q9 0 Mitogen-activated protein kinase 15 (EC 2.7.11.24) Xenopus laevis (African clawed frog) protein phosphorylation [GO:0006468]; regulation of cilium assembly [GO:1902017] GO:0004707; GO:0005524; GO:0005737; GO:0005911; GO:0005929; GO:0006468; GO:0035253; GO:0036064; GO:0106310; GO:1902017 3600 XM_044329230.1 14 7 31 4 6 NA NA NA NA NA NA 3601 XM_044325264.1 22 269 81 9 198 NA NA NA NA NA NA 3602 XM_029339012.2 359 216 178 229 214 NA NA NA NA NA NA 3603 XR_003824073.2 0 0 0 0 11 NA NA NA NA NA NA 3604 XM_029353467.2 0 0 0 0 15 A0FKN5 1.6e-126 NA NA NA NA 3605 XM_029332032.2 470 460 274 665 380 Q8N0X2 0 Sperm-associated antigen 16 protein (Pf20 protein homolog) Homo sapiens (Human) axoneme assembly [GO:0035082]; cerebrospinal fluid circulation [GO:0090660]; cilium assembly [GO:0060271]; mucociliary clearance [GO:0120197]; sperm axoneme assembly [GO:0007288] GO:0005576; GO:0005930; GO:0007288; GO:0035082; GO:0036126; GO:0060271; GO:0090660; GO:0120197; GO:1990716 3606 XM_044314540.1 13 125 18 2409 0 NA NA NA NA NA NA 3607 XM_029331189.2 848 432 297 691 402 P23416 2.22e-85 Glycine receptor subunit alpha-2 Homo sapiens (Human) cellular response to amino acid stimulus [GO:0071230]; cellular response to ethanol [GO:0071361]; cellular response to zinc ion [GO:0071294]; chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; neuropeptide signaling pathway [GO:0007218]; regulation of membrane potential [GO:0042391]; response to amino acid [GO:0043200]; signal transduction [GO:0007165]; synaptic transmission, glycinergic [GO:0060012] GO:0004888; GO:0005231; GO:0005886; GO:0007165; GO:0007218; GO:0007268; GO:0016594; GO:0016934; GO:0022852; GO:0030594; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0043200; GO:0045202; GO:0045211; GO:0046872; GO:0050877; GO:0060012; GO:0071230; GO:0071294; GO:0071361; GO:0098690; GO:1902476; GO:1904315 3608 XM_044307928.1 0 0 5 0 9 NA NA NA NA NA NA 3609 XM_029343455.2 11 39 0 0 0 NA NA NA NA NA NA 3610 XM_029338033.2 0 226 0 0 3 NA NA NA NA NA NA 3611 XM_029349588.2 1367 1155 589 2120 1076 NA NA NA NA NA NA 3612 XM_029334389.2 1137 608 239 399 487 A7S6M8 8.35e-37 Ragulator complex protein LAMTOR4 homolog (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 4) Nematostella vectensis (Starlet sea anemone) cellular response to amino acid stimulus [GO:0071230]; positive regulation of TOR signaling [GO:0032008]; protein localization to lysosome [GO:0061462]; regulation of cell size [GO:0008361] GO:0005764; GO:0008361; GO:0032008; GO:0061462; GO:0071230; GO:0071986 3613 XM_044307670.1 144 57 59 35 24 NA NA NA NA NA NA 3614 XM_029325975.2 0 0 0 0 67 NA NA NA NA NA NA 3615 XM_029330951.2 480 408 344 564 370 Q5PQS6 5.04e-95 Nonsense-mediated mRNA decay factor SMG9 Rattus norvegicus (Rat) brain development [GO:0007420]; eye development [GO:0001654]; heart development [GO:0007507]; in utero embryonic development [GO:0001701]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184] GO:0000184; GO:0001654; GO:0001701; GO:0007420; GO:0007507; GO:0042802 3616 XM_029338584.2 176 120 95 0 0 Q13976 0 cGMP-dependent protein kinase 1 (cGK 1) (cGK1) (EC 2.7.11.12) (cGMP-dependent protein kinase I) (cGKI) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cGMP-mediated signaling [GO:0019934]; collateral sprouting [GO:0048668]; dendrite development [GO:0016358]; forebrain development [GO:0030900]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; negative regulation of vascular associated smooth muscle cell proliferation [GO:1904706]; neuron migration [GO:0001764]; protein phosphorylation [GO:0006468]; regulation of GTPase activity [GO:0043087]; relaxation of vascular associated smooth muscle [GO:0060087]; signal transduction [GO:0007165] GO:0001764; GO:0004672; GO:0004692; GO:0005246; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005886; GO:0006468; GO:0007165; GO:0016358; GO:0019934; GO:0030036; GO:0030553; GO:0030900; GO:0042802; GO:0043087; GO:0048668; GO:0060087; GO:0090331; GO:0106310; GO:1904706; GO:1904753 3617 XM_044313750.1 144 131 134 93 260 NA NA NA NA NA NA 3618 XM_029330948.2 9 7 5 13 11 NA NA NA NA NA NA 3619 XM_029336446.2 39 14 3 21 36 P30937 4.49e-25 Somatostatin receptor type 4 (SS-4-R) (SS4-R) (SS4R) Rattus norvegicus (Rat) cell migration [GO:0016477]; cellular response to glucocorticoid stimulus [GO:0071385]; forebrain development [GO:0030900]; negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0106072]; neuropeptide signaling pathway [GO:0007218]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0004930; GO:0004994; GO:0005737; GO:0005886; GO:0007218; GO:0016477; GO:0030900; GO:0042277; GO:0042923; GO:0043005; GO:0070374; GO:0071385; GO:0090238; GO:0106072 3620 XM_044321718.1 61 0 11 62 26 P32297 9.39e-65 Neuronal acetylcholine receptor subunit alpha-3 Homo sapiens (Human) acetylcholine receptor signaling pathway [GO:0095500]; activation of transmembrane receptor protein tyrosine kinase activity [GO:0007171]; behavioral response to nicotine [GO:0035095]; chemical synaptic transmission [GO:0007268]; excitatory postsynaptic potential [GO:0060079]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; locomotory behavior [GO:0007626]; membrane depolarization [GO:0051899]; nervous system development [GO:0007399]; nervous system process [GO:0050877]; regulation of acetylcholine secretion, neurotransmission [GO:0014056]; regulation of dendrite morphogenesis [GO:0048814]; regulation of membrane potential [GO:0042391]; regulation of smooth muscle contraction [GO:0006940]; response to acetylcholine [GO:1905144]; signal transduction [GO:0007165]; synaptic transmission involved in micturition [GO:0060084]; synaptic transmission, cholinergic [GO:0007271] GO:0005231; GO:0005886; GO:0005892; GO:0006811; GO:0006940; GO:0007165; GO:0007171; GO:0007268; GO:0007271; GO:0007399; GO:0007626; GO:0014056; GO:0014069; GO:0015276; GO:0015464; GO:0016020; GO:0016607; GO:0022848; GO:0030425; GO:0030594; GO:0034220; GO:0035095; GO:0042166; GO:0042391; GO:0043005; GO:0043025; GO:0044853; GO:0045202; GO:0045211; GO:0048814; GO:0050877; GO:0051899; GO:0060079; GO:0060084; GO:0095500; GO:1904315; GO:1905144 3621 XM_029339017.2 2805 1106 1178 2334 2245 Q9Y6X9 0 ATPase MORC2 (EC 3.6.1.-) (MORC family CW-type zinc finger protein 2) (Zinc finger CW-type coiled-coil domain protein 1) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; chromatin remodeling [GO:0006338]; fatty acid metabolic process [GO:0006631]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; positive regulation of DNA methylation-dependent heterochromatin formation [GO:0090309] GO:0000287; GO:0000792; GO:0003682; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006338; GO:0006631; GO:0006974; GO:0008270; GO:0016363; GO:0016887; GO:0042393; GO:0042802; GO:0042803; GO:0045814; GO:0045869; GO:0090309 3622 XM_029340721.2 736 171 187 790 301 Q3UZD5 2.48e-35 Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.361) (PR domain zinc finger protein 6) (PR domain-containing protein 6) (PR domain-containing protein in smooth muscle) Mus musculus (Mouse) chromatin organization [GO:0006325]; histone methylation [GO:0016571]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of smooth muscle cell differentiation [GO:0051151]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of gene expression [GO:0010468] GO:0000122; GO:0005634; GO:0006325; GO:0010468; GO:0016571; GO:0022008; GO:0042802; GO:0045892; GO:0046872; GO:0051151; GO:0140944 3623 XM_044322518.1 284 158 129 270 143 Q5REP9 6.03e-55 Kelch-like protein 3 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) distal tubule morphogenesis [GO:0072156]; ion homeostasis [GO:0050801]; protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination [GO:0016567]; renal sodium ion absorption [GO:0070294]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0003779; GO:0005829; GO:0005856; GO:0006511; GO:0016567; GO:0031463; GO:0050801; GO:0070294; GO:0070936; GO:0072156 3624 XR_006395093.1 166 132 56 145 160 NA NA NA NA NA NA 3625 XM_029338729.2 3564 2382 2046 3425 4113 NA NA NA NA NA NA 3626 XM_044327172.1 26 28 11 12 0 NA NA NA NA NA NA 3627 XM_029338839.2 159 45 75 78 202 O88871 2.3e-138 Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51) Rattus norvegicus (Rat) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; gamma-aminobutyric acid signaling pathway [GO:0007214]; neuron-glial cell signaling [GO:0150099]; synaptic transmission, GABAergic [GO:0051932] GO:0004888; GO:0004965; GO:0005737; GO:0005886; GO:0007193; GO:0007214; GO:0016020; GO:0030425; GO:0038039; GO:0042734; GO:0043005; GO:0043204; GO:0045211; GO:0046982; GO:0051932; GO:0098978; GO:0098982; GO:0150099; GO:1902710; GO:1902712 3628 XM_044306985.1 120 76 76 113 255 NA NA NA NA NA NA 3629 XM_044311915.1 1 25 54 15 1 NA NA NA NA NA NA 3630 XM_029356922.2 483 51 628 343 808 NA NA NA NA NA NA 3631 XM_029330437.2 3 17 0 0 3 NA NA NA NA NA NA 3632 XM_029339056.2 562 668 438 670 622 Q1MTN8 1.4e-33 Probable assembly chaperone of rpl4 Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) ribosomal large subunit assembly [GO:0000027] GO:0000027; GO:0005634; GO:0005730; GO:0005737; GO:0140597 3633 XM_044322232.1 3 0 4 25 7 NA NA NA NA NA NA 3634 XR_006396515.1 438 282 366 441 617 NA NA NA NA NA NA 3635 XM_044315464.1 38 0 22 53 28 O43422 2.91e-38 52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (Death-associated protein 4) (THAP domain-containing protein 0) (THAP domain-containing protein 12) Homo sapiens (Human) negative regulation of cell population proliferation [GO:0008285]; signal transduction [GO:0007165] GO:0003677; GO:0005634; GO:0007165; GO:0008285; GO:0046872; GO:0046983 3636 XM_044328976.1 0 0 10 0 13 Q5F408 2.7e-61 Cysteine--tRNA ligase, cytoplasmic (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS) Gallus gallus (Chicken) cysteinyl-tRNA aminoacylation [GO:0006423] GO:0000049; GO:0004817; GO:0005524; GO:0005737; GO:0006423; GO:0046872 3637 XM_044328976.1 0 0 10 0 13 Q5F408 2.7e-61 Cysteine--tRNA ligase, cytoplasmic (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS) Gallus gallus (Chicken) cysteinyl-tRNA aminoacylation [GO:0006423] GO:0000049; GO:0004817; GO:0005524; GO:0005737; GO:0006423; GO:0046872 3638 XM_029353076.2 0 0 5 6 7 NA NA NA NA NA NA 3639 XM_029333232.2 2422 997 1378 2260 2273 P11029 0 Acetyl-CoA carboxylase (ACC) (EC 6.4.1.2) [Includes: Biotin carboxylase (EC 6.3.4.14)] Gallus gallus (Chicken) epigenetic regulation of gene expression [GO:0040029]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; regulation of biological quality [GO:0065008]; response to carbohydrate [GO:0009743]; response to fatty acid [GO:0070542]; response to thyroid hormone [GO:0097066]; transport [GO:0006810] GO:0003989; GO:0004075; GO:0005102; GO:0005524; GO:0005737; GO:0005739; GO:0006633; GO:0006810; GO:0009374; GO:0009743; GO:0010628; GO:0032810; GO:0040029; GO:0045893; GO:0046872; GO:0046966; GO:0050692; GO:0065008; GO:0070542; GO:0097066; GO:2001295 3640 XM_044325527.1 692 383 480 594 928 P35601 0 Replication factor C subunit 1 (A1-P145) (Activator 1 140 kDa subunit) (A1 140 kDa subunit) (Activator 1 large subunit) (Activator 1 subunit 1) (Differentiation-specific element-binding protein) (ISRE-binding protein) (Replication factor C 140 kDa subunit) (RF-C 140 kDa subunit) (RFC140) (Replication factor C large subunit) Mus musculus (Mouse) DNA repair [GO:0006281]; DNA replication [GO:0006260]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893] GO:0000122; GO:0003677; GO:0003689; GO:0003690; GO:0005524; GO:0005634; GO:0005654; GO:0005663; GO:0005730; GO:0005737; GO:0006260; GO:0006281; GO:0016887; GO:0019904; GO:0031391; GO:0032991; GO:0043565; GO:0045892; GO:0045893; GO:0061860 3641 XM_044322942.1 328 324 168 214 211 O60921 5.93e-106 Checkpoint protein HUS1 (hHUS1) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; cellular response to ionizing radiation [GO:0071479]; DNA damage checkpoint signaling [GO:0000077]; DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; embryo development ending in birth or egg hatching [GO:0009792]; meiotic DNA integrity checkpoint signaling [GO:0044778]; mitotic DNA replication checkpoint signaling [GO:0033314]; mitotic intra-S DNA damage checkpoint signaling [GO:0031573]; nucleotide-excision repair [GO:0006289]; protein phosphorylation [GO:0006468]; regulation of protein phosphorylation [GO:0001932]; response to UV [GO:0009411]; telomere maintenance [GO:0000723] GO:0000077; GO:0000723; GO:0000724; GO:0001932; GO:0005634; GO:0005654; GO:0005730; GO:0005829; GO:0006281; GO:0006289; GO:0006468; GO:0006974; GO:0009411; GO:0009792; GO:0030896; GO:0031573; GO:0033314; GO:0035861; GO:0044778; GO:0071479 3642 XM_044318173.1 1676 1569 817 1130 1539 Q8BLA8 5.02e-121 Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Wasabi receptor) Mus musculus (Mouse) calcium ion transmembrane import into cytosol [GO:0097553]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cell surface receptor signaling pathway [GO:0007166]; cellular calcium ion homeostasis [GO:0006874]; cellular response to carbon dioxide [GO:0071244]; cellular response to cold [GO:0070417]; cellular response to heat [GO:0034605]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to organic substance [GO:0071310]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; positive regulation of anion transport [GO:1903793]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of sensory perception of pain [GO:1904058]; protein homotetramerization [GO:0051289]; regulation of blood circulation [GO:1903522]; regulation of neuronal action potential [GO:0098908]; response to cold [GO:0009409]; response to hydrogen peroxide [GO:0042542]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; sensory perception of pain [GO:0019233]; thermoception [GO:0050955]; urinary bladder smooth muscle contraction [GO:0014832] GO:0005216; GO:0005245; GO:0005262; GO:0005886; GO:0006816; GO:0006874; GO:0007166; GO:0009409; GO:0009410; GO:0010033; GO:0014070; GO:0014832; GO:0015267; GO:0015278; GO:0016020; GO:0016324; GO:0019233; GO:0030424; GO:0032421; GO:0034605; GO:0035774; GO:0042542; GO:0042802; GO:0048265; GO:0050955; GO:0050966; GO:0050968; GO:0050974; GO:0051289; GO:0070301; GO:0070417; GO:0070588; GO:0071244; GO:0071310; GO:0097553; GO:0097604; GO:0098908; GO:1903522; GO:1903793; GO:1904058; GO:1990760 3643 XM_029340704.2 43 133 0 79 129 Q3UZD5 9.5e-44 Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.361) (PR domain zinc finger protein 6) (PR domain-containing protein 6) (PR domain-containing protein in smooth muscle) Mus musculus (Mouse) chromatin organization [GO:0006325]; histone methylation [GO:0016571]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of smooth muscle cell differentiation [GO:0051151]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of gene expression [GO:0010468] GO:0000122; GO:0005634; GO:0006325; GO:0010468; GO:0016571; GO:0022008; GO:0042802; GO:0045892; GO:0046872; GO:0051151; GO:0140944 3644 XM_029340704.2 43 133 0 79 129 Q3UZD5 4.71e-40 Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.361) (PR domain zinc finger protein 6) (PR domain-containing protein 6) (PR domain-containing protein in smooth muscle) Mus musculus (Mouse) chromatin organization [GO:0006325]; histone methylation [GO:0016571]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of smooth muscle cell differentiation [GO:0051151]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of gene expression [GO:0010468] GO:0000122; GO:0005634; GO:0006325; GO:0010468; GO:0016571; GO:0022008; GO:0042802; GO:0045892; GO:0046872; GO:0051151; GO:0140944 3645 XM_029340704.2 43 133 0 79 129 Q3UZD5 4.71e-40 Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.361) (PR domain zinc finger protein 6) (PR domain-containing protein 6) (PR domain-containing protein in smooth muscle) Mus musculus (Mouse) chromatin organization [GO:0006325]; histone methylation [GO:0016571]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of smooth muscle cell differentiation [GO:0051151]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of gene expression [GO:0010468] GO:0000122; GO:0005634; GO:0006325; GO:0010468; GO:0016571; GO:0022008; GO:0042802; GO:0045892; GO:0046872; GO:0051151; GO:0140944 3646 XM_029356614.2 351 407 269 438 287 Q5T8I3 8.04e-62 EEIG family member 2 (EEIG2) Homo sapiens (Human) NA NA 3647 XR_006393689.1 2040 808 563 1842 1442 NA NA NA NA NA NA 3648 XM_029344416.2 2539 991 1053 1863 2341 Q8TCJ2 0 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B (Oligosaccharyl transferase subunit STT3B) (STT3-B) (EC 2.4.99.18) (Source of immunodominant MHC-associated peptides homolog) Homo sapiens (Human) co-translational protein modification [GO:0043686]; glycoprotein catabolic process [GO:0006516]; post-translational protein modification [GO:0043687]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279]; response to unfolded protein [GO:0006986]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0004579; GO:0005783; GO:0005789; GO:0006487; GO:0006516; GO:0006986; GO:0008250; GO:0016020; GO:0018279; GO:0030433; GO:0032991; GO:0034998; GO:0043686; GO:0043687; GO:0046872 3649 XM_029337098.2 89 0 48 36 18 NA NA NA NA NA NA 3650 XM_044328998.1 12 16 14 10 27 Q9PTS8 3.02e-54 Neuronal acetylcholine receptor subunit alpha-9 (Nicotinic acetylcholine receptor subunit alpha-9) (NACHR alpha-9) Gallus gallus (Chicken) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; regulation of nitric oxide metabolic process [GO:0080164]; response to auditory stimulus [GO:0010996]; signal transduction [GO:0007165] GO:0004888; GO:0005231; GO:0005262; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0010996; GO:0022848; GO:0030594; GO:0034220; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051899; GO:0080164; GO:1904315 3651 XR_006393362.1 0 0 39 0 38 NA NA NA NA NA NA 3652 XM_044322438.1 93 58 86 151 138 Q9NXG6 5.43e-51 Transmembrane prolyl 4-hydroxylase (P4H-TM) (EC 1.14.11.29) (Hypoxia-inducible factor prolyl hydroxylase 4) (HIF-PH4) (HIF-prolyl hydroxylase 4) (HPH-4) Homo sapiens (Human) peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; regulation of erythrocyte differentiation [GO:0045646] GO:0004656; GO:0005506; GO:0005509; GO:0005783; GO:0005789; GO:0016706; GO:0018401; GO:0031418; GO:0045646 3653 XM_029330721.2 6515 4162 3120 6991 6636 Q28193 1.32e-179 Furin (EC 3.4.21.75) (Dibasic-processing enzyme) (Paired basic amino acid residue-cleaving enzyme) (PACE) (Trans Golgi network protease furin) Bos taurus (Bovine) positive regulation of transforming growth factor beta1 activation [GO:1901394]; proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0005794; GO:0005886; GO:0006508; GO:0008201; GO:0010008; GO:0046872; GO:1901394; GO:1904399 3654 XM_029352920.2 100 62 120 90 166 NA NA NA NA NA NA 3655 XM_029349456.2 211 167 103 229 133 NA NA NA NA NA NA 3656 XR_006392352.1 104 45 22 148 32 NA NA NA NA NA NA 3657 XM_029342241.2 24 84 150 118 35 Q9JJP6 8.01e-58 Tumor protein 63 (p63) (Keratinocyte transcription factor KET) (Transformation-related protein 63) (TP63) (Tumor protein p73-like) (p73L) Rattus norvegicus (Rat) aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; animal organ morphogenesis [GO:0009887]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular senescence [GO:0090398]; chromatin remodeling [GO:0006338]; cloacal septation [GO:0060197]; cranial skeletal system development [GO:1904888]; ectoderm and mesoderm interaction [GO:0007499]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; epidermal cell differentiation [GO:0009913]; epidermal cell division [GO:0010481]; epidermis development [GO:0008544]; epithelial cell development [GO:0002064]; epithelial cell differentiation [GO:0030855]; establishment of planar polarity [GO:0001736]; establishment of skin barrier [GO:0061436]; female genitalia morphogenesis [GO:0048807]; hair follicle development [GO:0001942]; hair follicle morphogenesis [GO:0031069]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; keratinocyte development [GO:0003334]; keratinocyte differentiation [GO:0030216]; keratinocyte proliferation [GO:0043616]; morphogenesis of a polarized epithelium [GO:0001738]; multicellular organism aging [GO:0010259]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of keratinocyte differentiation [GO:0045617]; negative regulation of mesoderm development [GO:2000381]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron apoptotic process [GO:0051402]; Notch signaling pathway [GO:0007219]; odontogenesis of dentin-containing tooth [GO:0042475]; pattern specification process [GO:0007389]; polarized epithelial cell differentiation [GO:0030859]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of fibroblast apoptotic process [GO:2000271]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of somatic stem cell population maintenance [GO:1904674]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; prostate gland development [GO:0030850]; prostatic bud formation [GO:0060513]; protein tetramerization [GO:0051262]; proximal/distal pattern formation [GO:0009954]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of epidermal cell division [GO:0010482]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal system development [GO:0001501]; skin epidermis development [GO:0098773]; skin morphogenesis [GO:0043589]; spermatogenesis [GO:0007283]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; stem cell differentiation [GO:0048863]; stem cell proliferation [GO:0072089]; sympathetic nervous system development [GO:0048485]; transcription by RNA polymerase II [GO:0006366] GO:0000122; GO:0000785; GO:0000978; GO:0000981; GO:0001228; GO:0001501; GO:0001736; GO:0001738; GO:0001942; GO:0002039; GO:0002064; GO:0003334; GO:0003677; GO:0003682; GO:0003684; GO:0003690; GO:0003700; GO:0005634; GO:0005654; GO:0005737; GO:0005791; GO:0006338; GO:0006357; GO:0006366; GO:0007219; GO:0007283; GO:0007389; GO:0007499; GO:0007568; GO:0008283; GO:0008284; GO:0008544; GO:0009887; GO:0009913; GO:0009954; GO:0010259; GO:0010481; GO:0010482; GO:0010838; GO:0019904; GO:0030154; GO:0030216; GO:0030326; GO:0030425; GO:0030850; GO:0030855; GO:0030859; GO:0031069; GO:0032991; GO:0033147; GO:0035115; GO:0035116; GO:0036342; GO:0042475; GO:0042771; GO:0042802; GO:0043005; GO:0043281; GO:0043565; GO:0043589; GO:0043616; GO:0045617; GO:0045669; GO:0045747; GO:0045892; GO:0045893; GO:0045944; GO:0046872; GO:0048485; GO:0048646; GO:0048807; GO:0048863; GO:0050699; GO:0051262; GO:0051402; GO:0060197; GO:0060513; GO:0060529; GO:0061436; GO:0072089; GO:0090398; GO:0097371; GO:0098773; GO:1904674; GO:1904888; GO:2000271; GO:2000381; GO:2000648; GO:2001235 3658 XR_006398078.1 443 153 86 54 0 NA NA NA NA NA NA 3659 XM_044315463.1 28 5 61 23 39 NA NA NA NA NA NA 3660 XR_006392187.1 384 82 107 295 65 NA NA NA NA NA NA 3661 XM_044315159.1 24 65 11 136 59 NA NA NA NA NA NA 3662 XM_044308962.1 10 0 17 4 11 NA NA NA NA NA NA 3663 XR_006391382.1 32 33 15 26 47 NA NA NA NA NA NA 3664 XM_029353714.2 1354 620 896 1620 1571 Q2TBI0 1.61e-70 Lipopolysaccharide-binding protein (LBP) Bos taurus (Bovine) cellular response to lipopolysaccharide [GO:0071222]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; lipid transport [GO:0006869]; macrophage activation involved in immune response [GO:0002281]; positive regulation of tumor necrosis factor production [GO:0032760] GO:0001530; GO:0002281; GO:0005615; GO:0006869; GO:0016020; GO:0032760; GO:0042742; GO:0045087; GO:0071222 3665 XM_044314212.1 21 0 2 2 33 NA NA NA NA NA NA 3666 XM_044324153.1 432 350 225 879 265 G3V9H8 1.62e-65 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Rattus norvegicus (Rat) cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0007156; GO:0007158; GO:0007169; GO:0007399; GO:0009410; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030182; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0098797 3667 XM_044323315.1 836 488 386 485 673 Q9ESL4 1.89e-174 Mitogen-activated protein kinase kinase kinase 20 (EC 2.7.11.25) (Leucine zipper- and sterile alpha motif kinase ZAK) (Leucine zipper- and sterile alpha motif-containing kinase) (MLK-like mitogen-activated protein triple kinase) (Mitogen-activated protein kinase kinase kinase MLT) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) Mus musculus (Mouse) cell cycle [GO:0007049]; cellular response to gamma radiation [GO:0071480]; cellular response to UV-B [GO:0071493]; cytoskeleton organization [GO:0007010]; DNA damage checkpoint signaling [GO:0000077]; embryonic digit morphogenesis [GO:0042733]; GCN2-mediated signaling [GO:0140469]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; limb development [GO:0060173]; p38MAPK cascade [GO:0038066]; positive regulation of apoptotic process [GO:0043065]; positive regulation of mitotic DNA damage checkpoint [GO:1904291]; positive regulation of programmed cell death [GO:0043068]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; pyroptosis [GO:0070269]; stress-activated MAPK cascade [GO:0051403]; stress-activated protein kinase signaling cascade [GO:0031098] GO:0000077; GO:0000287; GO:0004674; GO:0004706; GO:0004709; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006468; GO:0007010; GO:0007049; GO:0007254; GO:0030295; GO:0031098; GO:0035556; GO:0038066; GO:0042733; GO:0043022; GO:0043065; GO:0043068; GO:0046777; GO:0051403; GO:0060173; GO:0070181; GO:0070269; GO:0071480; GO:0071493; GO:0106310; GO:0140469; GO:1904291 3668 XM_044320485.1 427 0 190 175 0 Q9UNA1 5.63e-170 Rho GTPase-activating protein 26 (GTPase regulator associated with focal adhesion kinase) (Oligophrenin-1-like protein) (Rho-type GTPase-activating protein 26) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; nervous system development [GO:0007399]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] GO:0005096; GO:0005543; GO:0005829; GO:0005856; GO:0005925; GO:0007165; GO:0007399; GO:0030036; GO:0051056 3669 XM_029335327.2 630 345 242 662 660 Q9D6X6 5.81e-39 Serine protease 23 (EC 3.4.21.-) Mus musculus (Mouse) proteolysis [GO:0006508] GO:0004252; GO:0005615; GO:0005634; GO:0006508 3670 XM_029326913.2 142 17 39 91 130 NA NA NA NA NA NA 3671 XM_044318418.1 0 0 10 30 11 NA NA NA NA NA NA 3672 XR_003827618.2 1856 1398 928 4320 1038 NA NA NA NA NA NA 3673 XM_044327796.1 0 0 13 0 4 NA NA NA NA NA NA 3674 XM_029357474.2 836 651 379 427 345 NA NA NA NA NA NA 3675 XM_044317216.1 90 134 20 82 80 NA NA NA NA NA NA 3676 XM_029328009.2 1 154 5 29 147 NA NA NA NA NA NA 3677 XM_044328865.1 24 49 20 0 82 NA NA NA NA NA NA 3678 XR_006395905.1 1 7 0 40 3 NA NA NA NA NA NA 3679 XM_044325903.1 81 0 51 45 71 NA NA NA NA NA NA 3680 XM_044308782.1 332 350 305 158 522 NA NA NA NA NA NA 3681 XM_044307066.1 4 0 0 14 0 NA NA NA NA NA NA 3682 XM_029350975.2 692 619 125 492 584 NA NA NA NA NA NA 3683 XM_044307317.1 53 0 0 48 22 Q9UQQ1 6.04e-49 Aminopeptidase NAALADL1 (EC 3.4.11.-) (100 kDa ileum brush border membrane protein) (I100) (Ileal dipeptidylpeptidase) (N-acetylated-alpha-linked acidic dipeptidase-like protein) (NAALADase L) Homo sapiens (Human) peptide catabolic process [GO:0043171]; proteolysis [GO:0006508] GO:0004177; GO:0004180; GO:0005509; GO:0006508; GO:0008233; GO:0008237; GO:0008270; GO:0016020; GO:0016324; GO:0042803; GO:0043171 3684 XM_044307317.1 53 0 0 48 22 Q9UQQ1 6.04e-49 Aminopeptidase NAALADL1 (EC 3.4.11.-) (100 kDa ileum brush border membrane protein) (I100) (Ileal dipeptidylpeptidase) (N-acetylated-alpha-linked acidic dipeptidase-like protein) (NAALADase L) Homo sapiens (Human) peptide catabolic process [GO:0043171]; proteolysis [GO:0006508] GO:0004177; GO:0004180; GO:0005509; GO:0006508; GO:0008233; GO:0008237; GO:0008270; GO:0016020; GO:0016324; GO:0042803; GO:0043171 3685 XM_044310856.1 227 528 174 358 170 Q7RTR2 2.88e-44 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 3686 XM_044310856.1 227 528 174 358 170 Q7RTR2 1.83e-42 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 3687 XM_044310856.1 227 528 174 358 170 Q7RTR2 2.48e-42 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 3688 XM_044310856.1 227 528 174 358 170 Q7RTR2 2.4e-34 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 3689 XM_044310856.1 227 528 174 358 170 Q7RTR2 6.8e-31 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 3690 XM_044310856.1 227 528 174 358 170 Q7RTR2 8.08e-30 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 3691 XM_029342088.2 836 508 531 819 860 O08684 0 Phospholipase D1 (PLD 1) (EC 3.1.4.4) (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D1) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) inositol lipid-mediated signaling [GO:0048017]; lipid catabolic process [GO:0016042]; phosphatidic acid biosynthetic process [GO:0006654] GO:0000139; GO:0004630; GO:0005789; GO:0006654; GO:0016042; GO:0031902; GO:0035091; GO:0048017; GO:0048471; GO:0070290 3692 XM_044321621.1 250 205 163 264 367 Q5T7V8 6.44e-22 RAB6-interacting golgin (N-terminal kinase-like-binding protein 1) (NTKL-BP1) (NTKL-binding protein 1) (hNTKL-BP1) (SCY1-like 1-binding protein 1) (SCYL1-BP1) (SCYL1-binding protein 1) Homo sapiens (Human) hair follicle morphogenesis [GO:0031069]; non-motile cilium assembly [GO:1905515]; positive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:1901622] GO:0005654; GO:0005730; GO:0005737; GO:0005794; GO:0005829; GO:0031069; GO:1901622; GO:1905515 3693 XM_029336056.2 775 592 447 327 450 Q8VBX0 9.16e-31 Ankyrin repeat and SOCS box protein 13 (ASB-13) Mus musculus (Mouse) intracellular signal transduction [GO:0035556]; protein ubiquitination [GO:0016567] GO:0016567; GO:0035556 3694 XM_044307692.1 660 715 105 266 113 P40392 3.81e-32 Ras-related protein RIC1 Oryza sativa subsp. japonica (Rice) protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] GO:0003924; GO:0005525; GO:0005886; GO:0015031; GO:0016192 3695 XM_044322930.1 63 68 25 59 111 NA NA NA NA NA NA 3696 XM_029333337.2 178 11 0 307 129 NA NA NA NA NA NA 3697 XM_029333825.2 142 85 113 161 224 Q9C026 0 E3 ubiquitin-protein ligase TRIM9 (EC 2.3.2.27) (RING finger protein 91) (RING-type E3 ubiquitin transferase TRIM9) (Tripartite motif-containing protein 9) Homo sapiens (Human) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] GO:0005737; GO:0005856; GO:0008021; GO:0008270; GO:0019904; GO:0030425; GO:0042803; GO:0043161; GO:0061630 3698 XM_044320005.1 813 832 268 1468 949 P97846 5.99e-37 Contactin-associated protein 1 (Caspr) (Caspr1) (Neurexin IV) (Neurexin-4) (Paranodin) (p190) Rattus norvegicus (Rat) axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cytoskeleton organization [GO:0007010]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process [GO:0050905]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuronal action potential propagation [GO:0019227]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; postsynaptic density organization [GO:0097106]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; regulation of synapse maturation [GO:0090128] GO:0002175; GO:0007005; GO:0007010; GO:0007155; GO:0007409; GO:0016020; GO:0017124; GO:0019227; GO:0022010; GO:0022011; GO:0030424; GO:0030913; GO:0031175; GO:0033010; GO:0033270; GO:0042552; GO:0048786; GO:0048812; GO:0050884; GO:0050885; GO:0050905; GO:0071205; GO:0090128; GO:0097106; GO:0098529; GO:0098978; GO:1990227 3699 XM_029353954.2 318 293 245 223 119 NA NA NA NA NA NA 3700 XM_029357930.2 0 3 0 24 0 NA NA NA NA NA NA 3701 XM_044321283.1 6 0 37 12 79 P04323 1.48e-76 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 3702 XM_029350929.2 598 521 316 383 483 A0JMY5 0 NF-X1-type zinc finger protein NFXL1 Xenopus laevis (African clawed frog) NA GO:0003700; GO:0005634; GO:0008270; GO:0016020 3703 XR_006396430.1 264 226 109 224 371 B8UU78 8.14e-66 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 3704 XM_029329977.2 10 0 8 1 5 Q32LL6 8.08e-41 MORN repeat-containing protein 5 Bos taurus (Bovine) NA NA 3705 XM_044329161.1 675 622 457 883 883 NA NA NA NA NA NA 3706 XR_006396791.1 46 1 59 51 49 NA NA NA NA NA NA 3707 XM_044312758.1 0 0 0 0 13 NA NA NA NA NA NA 3708 XM_029350831.2 5 0 6 3 32 Q9D411 1.34e-88 Testis-specific serine/threonine-protein kinase 4 (TSK-4) (TSSK-4) (Testis-specific kinase 4) (EC 2.7.11.1) Mus musculus (Mouse) fertilization [GO:0009566]; flagellated sperm motility [GO:0030317]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine autophosphorylation [GO:1990443]; positive regulation of CREB transcription factor activity [GO:0032793]; protein phosphorylation [GO:0006468]; spermatid development [GO:0007286] GO:0000287; GO:0001669; GO:0004672; GO:0004674; GO:0005524; GO:0006468; GO:0007286; GO:0009566; GO:0018105; GO:0030317; GO:0031514; GO:0032793; GO:0035556; GO:0036126; GO:0042802; GO:0042803; GO:0044877; GO:0106310; GO:1990443 3709 XM_044323540.1 62 21 15 17 102 NA NA NA NA NA NA 3710 XM_029339919.2 257 520 138 281 323 P31422 0 Metabotropic glutamate receptor 3 (mGluR3) Rattus norvegicus (Rat) G protein-coupled glutamate receptor signaling pathway [GO:0007216]; gene expression [GO:0010467]; modulation of chemical synaptic transmission [GO:0050804]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; regulation of synaptic transmission, glutamatergic [GO:0051966]; sensory perception of pain [GO:0019233] GO:0001640; GO:0001641; GO:0005246; GO:0005886; GO:0007216; GO:0010467; GO:0014069; GO:0019233; GO:0030424; GO:0042734; GO:0043005; GO:0043197; GO:0045211; GO:0050804; GO:0051966; GO:0097110; GO:0097449; GO:0098794; GO:0098978; GO:0099170 3711 XM_029331264.2 28 0 0 11 26 NA NA NA NA NA NA 3712 XM_044328434.1 787 452 378 535 564 Q3U3R4 0 Lipase maturation factor 1 (Transmembrane protein 112) Mus musculus (Mouse) chylomicron remnant clearance [GO:0034382]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of lipoprotein lipase activity [GO:0051006]; protein glycosylation [GO:0006486]; protein maturation [GO:0051604]; protein secretion [GO:0009306]; regulation of cholesterol metabolic process [GO:0090181]; regulation of triglyceride metabolic process [GO:0090207]; triglyceride metabolic process [GO:0006641] GO:0005789; GO:0006486; GO:0006641; GO:0006888; GO:0009306; GO:0034382; GO:0051006; GO:0051604; GO:0090181; GO:0090207 3713 XR_003826107.2 3 1 0 7 5 NA NA NA NA NA NA 3714 XM_029345150.2 128 25 88 59 132 NA NA NA NA NA NA 3715 XR_006394793.1 0 13 0 0 0 NA NA NA NA NA NA 3716 XM_029335439.2 89 9 153 0 0 NA NA NA NA NA NA 3717 XM_029345887.2 781 934 488 912 928 Q6NTU3 1.97e-33 Mitochondrial import inner membrane translocase subunit tim16-A (Presequence translocated-associated motor subunit pam16-A) Xenopus laevis (African clawed frog) protein import into mitochondrial matrix [GO:0030150] GO:0005744; GO:0030150 3718 XM_029338519.2 654 568 709 859 500 P27465 8.77e-112 Phosphatidylserine decarboxylase proenzyme, mitochondrial (EC 4.1.1.65) [Cleaved into: Phosphatidylserine decarboxylase beta chain; Phosphatidylserine decarboxylase alpha chain] Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) lipid droplet formation [GO:0140042]; mitochondrial protein catabolic process [GO:0035694]; phosphatidylethanolamine biosynthetic process [GO:0006646]; protein autoprocessing [GO:0016540]; regulation of mitochondrion organization [GO:0010821] GO:0004609; GO:0005634; GO:0005739; GO:0005743; GO:0005811; GO:0006646; GO:0010821; GO:0016540; GO:0035694; GO:0140042 3719 XM_029331845.2 55 37 58 0 51 Q5RJA1 0 DNA-binding protein RFX6 (Regulatory factor X 6) Danio rerio (Zebrafish) (Brachydanio rerio) endocrine pancreas development [GO:0031018]; glucose homeostasis [GO:0042593]; pancreatic A cell differentiation [GO:0003310]; pancreatic D cell differentiation [GO:0003311]; pancreatic epsilon cell differentiation [GO:0090104]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of insulin secretion [GO:0050796]; regulation of transcription by RNA polymerase II [GO:0006357]; type B pancreatic cell differentiation [GO:0003309] GO:0000976; GO:0000978; GO:0000981; GO:0003309; GO:0003310; GO:0003311; GO:0005634; GO:0006357; GO:0031018; GO:0035774; GO:0042593; GO:0045893; GO:0045944; GO:0050796; GO:0090104 3720 XR_006395442.1 0 0 1 0 15 NA NA NA NA NA NA 3721 XM_044317868.1 1 3 0 46 0 Q96CG8 8.67e-40 Collagen triple helix repeat-containing protein 1 Homo sapiens (Human) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005576; GO:0005581; GO:0005615; GO:0016477; GO:0016528; GO:0017147; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0062023; GO:0090090; GO:0090103; GO:0090177 3722 XM_044316676.1 561 163 135 544 369 Q8R3B7 2.08e-59 Bromodomain-containing protein 8 Mus musculus (Mouse) cellular response to thyroid hormone stimulus [GO:0097067]; chromatin organization [GO:0006325]; histone acetylation [GO:0016573]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of double-strand break repair [GO:2000779] GO:0000786; GO:0000812; GO:0005654; GO:0005739; GO:0006325; GO:0016573; GO:0030374; GO:0035267; GO:0042981; GO:0043967; GO:0043968; GO:0045893; GO:0045944; GO:0046966; GO:0051726; GO:0097067; GO:1905168; GO:2000779 3723 XM_044316676.1 561 163 135 544 369 Q8R3B7 1.14e-38 Bromodomain-containing protein 8 Mus musculus (Mouse) cellular response to thyroid hormone stimulus [GO:0097067]; chromatin organization [GO:0006325]; histone acetylation [GO:0016573]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of double-strand break repair [GO:2000779] GO:0000786; GO:0000812; GO:0005654; GO:0005739; GO:0006325; GO:0016573; GO:0030374; GO:0035267; GO:0042981; GO:0043967; GO:0043968; GO:0045893; GO:0045944; GO:0046966; GO:0051726; GO:0097067; GO:1905168; GO:2000779 3724 XM_029331044.2 787 837 460 910 784 Q9H8V3 0 Protein ECT2 (Epithelial cell-transforming sequence 2 oncogene) Homo sapiens (Human) activation of GTPase activity [GO:0090630]; activation of protein kinase activity [GO:0032147]; bicellular tight junction assembly [GO:0070830]; cell differentiation [GO:0030154]; cell morphogenesis [GO:0000902]; cellular response to calcium ion [GO:0071277]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to ionizing radiation [GO:0071479]; intracellular signal transduction [GO:0035556]; mitotic cytokinesis [GO:0000281]; nervous system development [GO:0007399]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cytokinesis [GO:0032467]; positive regulation of GTPase activity [GO:0043547]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of protein import into nucleus [GO:0042307]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cytokinesis, actomyosin contractile ring assembly [GO:2000431]; regulation of protein kinase activity [GO:0045859]; regulation of small GTPase mediated signal transduction [GO:0051056] GO:0000281; GO:0000902; GO:0005085; GO:0005096; GO:0005634; GO:0005654; GO:0005737; GO:0005815; GO:0005829; GO:0005911; GO:0005923; GO:0005938; GO:0007399; GO:0015031; GO:0016604; GO:0030154; GO:0030496; GO:0031267; GO:0032147; GO:0032154; GO:0032467; GO:0035556; GO:0042307; GO:0042803; GO:0043065; GO:0043123; GO:0043547; GO:0045666; GO:0045859; GO:0051056; GO:0051260; GO:0051988; GO:0070301; GO:0070830; GO:0071277; GO:0071479; GO:0072686; GO:0090630; GO:0097149; GO:2000431 3725 XM_029340663.2 159 94 95 101 139 Q86TP1 1.43e-64 Exopolyphosphatase PRUNE1 (EC 3.6.1.1) (Drosophila-related expressed sequence 17) (DRES-17) (DRES17) (HTcD37) (Protein prune homolog 1) (hPrune) Homo sapiens (Human) regulation of microtubule polymerization [GO:0031113]; regulation of neurogenesis [GO:0050767] GO:0004309; GO:0004427; GO:0005634; GO:0005737; GO:0005829; GO:0005925; GO:0015631; GO:0016791; GO:0031113; GO:0046872; GO:0050767 3726 XR_006392236.1 63 395 33 89 134 NA NA NA NA NA NA 3727 XM_044315774.1 10 0 3 4 0 NA NA NA NA NA NA 3728 XM_044323806.1 24 67 98 9 4 NA NA NA NA NA NA 3729 XM_044310064.1 316 96 0 54 178 O22943 3.89e-85 Probable glycosyltransferase STELLO1 (EC 2.4.-.-) Arabidopsis thaliana (Mouse-ear cress) plant-type cell wall cellulose biosynthetic process [GO:0052324]; regulation of plant-type cell wall cellulose biosynthetic process [GO:2001009] GO:0000139; GO:0005768; GO:0005794; GO:0005802; GO:0016757; GO:0042802; GO:0052324; GO:2001009 3730 XM_029357586.2 281 134 126 175 181 NA NA NA NA NA NA 3731 XM_044325416.1 34 23 17 17 20 NA NA NA NA NA NA 3732 XM_029329946.2 20 17 8 27 10 P17971 3.67e-87 Potassium voltage-gated channel protein Shal (Shaker cognate l) (Shal2) Drosophila melanogaster (Fruit fly) associative learning [GO:0008306]; chemical synaptic transmission [GO:0007268]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005250; GO:0005886; GO:0006813; GO:0007268; GO:0008076; GO:0008306; GO:0016020; GO:0030425; GO:0034765; GO:0043204; GO:0045202; GO:0051260; GO:0071805 3733 XM_044322397.1 369 266 0 0 11 Q96AY4 5.39e-94 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3734 XM_044322397.1 369 266 0 0 11 Q96AY4 2.23e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3735 XM_044322397.1 369 266 0 0 11 Q96AY4 2.49e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3736 XM_044322397.1 369 266 0 0 11 Q96AY4 2.01e-83 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3737 XM_044322397.1 369 266 0 0 11 Q96AY4 3.83e-83 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3738 XM_044322397.1 369 266 0 0 11 Q96AY4 8.87e-82 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3739 XM_044322397.1 369 266 0 0 11 Q96AY4 1.93e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3740 XM_029328150.2 86 60 49 48 57 G8HTB6 5.35e-48 ZP domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 3741 XM_029338256.2 1351 1354 918 1442 1629 Q02427 2.98e-22 RNA-binding protein 1 Drosophila melanogaster (Fruit fly) mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of gene expression [GO:0010468]; regulation of mRNA 3'-end processing [GO:0031440]; regulation of transcriptional start site selection at RNA polymerase II promoter [GO:0001178]; RNA splicing [GO:0008380] GO:0000381; GO:0000398; GO:0000791; GO:0001178; GO:0003723; GO:0003729; GO:0005634; GO:0008380; GO:0010468; GO:0016607; GO:0031440; GO:0045292 3742 XR_006391464.1 8 2 0 12 31 Q4KWL2 1.49e-22 Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor) Tscherskia triton (Greater long-tailed hamster) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; blood vessel diameter maintenance [GO:0097746]; positive regulation of autophagosome maturation [GO:1901098]; positive regulation of lipophagy [GO:1904504]; regulation of smooth muscle contraction [GO:0006940] GO:0004941; GO:0005769; GO:0005794; GO:0005886; GO:0006940; GO:0007189; GO:0097746; GO:1901098; GO:1904504 3743 XR_006391464.1 8 2 0 12 31 Q4KWL2 1.49e-22 Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor) Tscherskia triton (Greater long-tailed hamster) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; blood vessel diameter maintenance [GO:0097746]; positive regulation of autophagosome maturation [GO:1901098]; positive regulation of lipophagy [GO:1904504]; regulation of smooth muscle contraction [GO:0006940] GO:0004941; GO:0005769; GO:0005794; GO:0005886; GO:0006940; GO:0007189; GO:0097746; GO:1901098; GO:1904504 3744 XM_044313418.1 591 2684 912 5703 2245 D9IQ16 1.1e-25 Galaxin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 3745 XM_029339094.2 269 98 216 497 366 Q9CYL5 5.2e-36 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Mus musculus (Mouse) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070374 3746 XM_044311552.1 0 0 0 0 21 NA NA NA NA NA NA 3747 XM_029343313.2 21920 26475 17002 13470 10319 O75506 1.64e-24 Heat shock factor-binding protein 1 (Nasopharyngeal carcinoma-associated antigen 13) (NPC-A-13) Homo sapiens (Human) axonal transport of mitochondrion [GO:0019896]; cellular heat acclimation [GO:0070370]; negative regulation of transcription by RNA polymerase II [GO:0000122] GO:0000122; GO:0003714; GO:0005634; GO:0005654; GO:0005829; GO:0019896; GO:0042802; GO:0070370; GO:1904115 3748 XM_044323333.1 139 110 273 247 251 NA NA NA NA NA NA 3749 XM_044308169.1 187 120 222 308 191 NA NA NA NA NA NA 3750 XR_006396048.1 112 69 276 125 355 NA NA NA NA NA NA 3751 XM_029347619.2 798 403 3 491 388 NA NA NA NA NA NA 3752 XR_006394417.1 79 19 16 38 56 NA NA NA NA NA NA 3753 XM_029323635.2 371 441 291 420 300 Q8TCB7 2.13e-112 tRNA N(3)-methylcytidine methyltransferase METTL6 (EC 2.1.1.-) (Methyltransferase-like protein 6) (hMETTL6) Homo sapiens (Human) tRNA methylation [GO:0030488] GO:0005634; GO:0005737; GO:0019899; GO:0030488; GO:0052735 3754 XM_029350529.2 21 27 4 56 10 O42127 6.47e-59 Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) Xenopus laevis (African clawed frog) apoptotic process [GO:0006915]; positive regulation of cell population proliferation [GO:0008284] GO:0005007; GO:0005524; GO:0005886; GO:0006915; GO:0008284 3755 XM_044314434.1 434 259 298 495 561 NA NA NA NA NA NA 3756 XM_044322830.1 42 15 0 19 5 NA NA NA NA NA NA 3757 XM_029335148.2 790 576 424 716 966 O55173 0 3-phosphoinositide-dependent protein kinase 1 (EC 2.7.11.1) (Protein kinase B kinase) (PkB kinase) Rattus norvegicus (Rat) activation of protein kinase B activity [GO:0032148]; calcium-mediated signaling [GO:0019722]; cell migration [GO:0016477]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to insulin stimulus [GO:0032869]; epidermal growth factor receptor signaling pathway [GO:0007173]; extrinsic apoptotic signaling pathway [GO:0097191]; focal adhesion assembly [GO:0048041]; hyperosmotic response [GO:0006972]; insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009]; intracellular signal transduction [GO:0035556]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; protein phosphorylation [GO:0006468]; regulation of endothelial cell migration [GO:0010594]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mast cell degranulation [GO:0043304]; type B pancreatic cell development [GO:0003323] GO:0003323; GO:0004672; GO:0004674; GO:0004676; GO:0005158; GO:0005524; GO:0005547; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0005925; GO:0006468; GO:0006469; GO:0006972; GO:0007173; GO:0008286; GO:0010518; GO:0010594; GO:0010667; GO:0014069; GO:0016004; GO:0016477; GO:0018105; GO:0018107; GO:0019209; GO:0019722; GO:0019901; GO:0030295; GO:0030512; GO:0031410; GO:0032148; GO:0032869; GO:0034122; GO:0035556; GO:0042995; GO:0043122; GO:0043204; GO:0043274; GO:0043304; GO:0043524; GO:0043536; GO:0043539; GO:0045766; GO:0048009; GO:0048041; GO:0051281; GO:0071364; GO:0097191; GO:0106310; GO:1903078; GO:1903672; GO:1905564; GO:1990416; GO:2000352 3758 XM_029334955.2 1370 938 514 1136 913 Q27294 2.9e-22 RNA-binding protein cabeza (P19) (Sarcoma-associated RNA-binding fly homolog) Drosophila melanogaster (Fruit fly) adult locomotory behavior [GO:0008344]; compound eye development [GO:0048749]; larval locomotory behavior [GO:0008345]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of synaptic assembly at neuromuscular junction [GO:0045887]; regulation of DNA-templated transcription [GO:0006355]; synaptic assembly at neuromuscular junction [GO:0051124]; transcription initiation at RNA polymerase II promoter [GO:0006367] GO:0000398; GO:0003682; GO:0003712; GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0005669; GO:0006355; GO:0006367; GO:0008344; GO:0008345; GO:0045887; GO:0046872; GO:0048749; GO:0051124; GO:0071013 3759 XM_029356183.2 93 12 68 95 150 Q9GJS9 2.94e-59 Glycine receptor subunit beta (Glycine receptor 58 kDa subunit) Bos taurus (Bovine) acrosome reaction [GO:0007340]; adult walking behavior [GO:0007628]; chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid receptor clustering [GO:0097112]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; nervous system development [GO:0007399]; nervous system process [GO:0050877]; neuropeptide signaling pathway [GO:0007218]; regulation of membrane potential [GO:0042391]; response to amino acid [GO:0043200]; righting reflex [GO:0060013]; signal transduction [GO:0007165]; startle response [GO:0001964]; synaptic transmission, glycinergic [GO:0060012]; visual perception [GO:0007601] GO:0001964; GO:0004888; GO:0005231; GO:0005737; GO:0005886; GO:0006811; GO:0007165; GO:0007218; GO:0007268; GO:0007340; GO:0007399; GO:0007601; GO:0007628; GO:0016594; GO:0016933; GO:0016934; GO:0016935; GO:0030425; GO:0030594; GO:0034220; GO:0042391; GO:0043005; GO:0043200; GO:0045202; GO:0045211; GO:0050877; GO:0060012; GO:0060013; GO:0097112; GO:0098690; GO:0098982; GO:1902476; GO:1904315 3760 XM_044317318.1 1041 760 243 686 765 Q6P9P6 0 Kinesin-like protein KIF11 (Kinesin-related motor protein Eg5) Mus musculus (Mouse) cell division [GO:0051301]; microtubule-based movement [GO:0007018]; mitotic centrosome separation [GO:0007100]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly [GO:0090307]; regulation of mitotic centrosome separation [GO:0046602]; spindle assembly [GO:0051225]; spindle elongation [GO:0051231]; spindle organization [GO:0007051] GO:0000070; GO:0000922; GO:0005524; GO:0005634; GO:0005819; GO:0005829; GO:0005874; GO:0005876; GO:0007018; GO:0007051; GO:0007100; GO:0008017; GO:0008574; GO:0019901; GO:0032991; GO:0046602; GO:0051225; GO:0051231; GO:0051301; GO:0072686; GO:0090307 3761 XM_044315984.1 0 57 0 0 8 A3KN83 0 Protein strawberry notch homolog 1 (Monocyte protein 3) (MOP-3) Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355]; regulation of response to stimulus [GO:0048583] GO:0005634; GO:0006355; GO:0031490; GO:0042393; GO:0048583 3762 XM_029337737.2 103 183 97 293 374 NA NA NA NA NA NA 3763 XM_029331696.2 22 0 0 53 0 Q3YEC7 9.16e-86 Rab-like protein 6 (GTP-binding protein Parf) (Partner of ARF) (Rab-like protein 1) (RBEL1) Homo sapiens (Human) NA GO:0003924; GO:0005525; GO:0005634; GO:0005737; GO:0005813; GO:0005829 3764 XR_006392358.1 12 0 0 0 7 NA NA NA NA NA NA 3765 XM_029328226.2 26659 30150 15540 32908 34203 B8VIW9 5.81e-106 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 3766 XM_029339769.2 923 352 0 352 922 Q8K370 0 Acyl-CoA dehydrogenase family member 10 (ACAD-10) (EC 1.3.99.-) Mus musculus (Mouse) fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539] GO:0003995; GO:0005737; GO:0005739; GO:0033539; GO:0050660 3767 XR_006394254.1 11 4 43 9 189 NA NA NA NA NA NA 3768 XM_044327125.1 37 0 0 34 132 O70521 1.03e-31 Regulator of G-protein signaling 19 (RGS19) (G-alpha-interacting protein) (GAIP) Rattus norvegicus (Rat) negative regulation of signal transduction [GO:0009968]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; response to ethanol [GO:0045471] GO:0000139; GO:0001965; GO:0005096; GO:0005737; GO:0005903; GO:0008277; GO:0009968; GO:0016020; GO:0030136; GO:0045121; GO:0045471 3769 XR_006391742.1 0 33 16 1 13 NA NA NA NA NA NA 3770 XR_006394273.1 18 14 22 47 104 NA NA NA NA NA NA 3771 XM_029330698.2 1403 1935 1222 1162 1759 P56377 2.2e-83 AP-1 complex subunit sigma-2 (Adaptor protein complex AP-1 subunit sigma-1B) (Adaptor-related protein complex 1 subunit sigma-1B) (Clathrin assembly protein complex 1 sigma-1B small chain) (Golgi adaptor HA1/AP1 adaptin sigma-1B subunit) (Sigma 1B subunit of AP-1 clathrin) (Sigma-adaptin 1B) (Sigma1B-adaptin) Homo sapiens (Human) intracellular protein transport [GO:0006886]; melanosome assembly [GO:1903232]; platelet dense granule organization [GO:0060155]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0005765; GO:0005769; GO:0005794; GO:0005829; GO:0005905; GO:0006886; GO:0016192; GO:0030119; GO:0030121; GO:0030659; GO:0032588; GO:0035615; GO:0043231; GO:0060155; GO:1903232 3772 XM_029335619.2 45 53 28 61 65 NA NA NA NA NA NA 3773 XM_029344981.2 493 767 844 434 867 Q8NF64 5.3e-140 Zinc finger MIZ domain-containing protein 2 (PIAS-like protein Zimp7) Homo sapiens (Human) positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0005634; GO:0005654; GO:0005739; GO:0006357; GO:0008270; GO:0030374; GO:0043596; GO:0045944 3774 XM_029347378.2 0 0 0 249 751 NA NA NA NA NA NA 3775 XM_029336091.2 0 9 0 4 26 NA NA NA NA NA NA 3776 XM_029337208.2 5187 2249 2602 5663 5049 Q9P281 3.12e-37 BAH and coiled-coil domain-containing protein 1 (Bromo adjacent homology domain-containing protein 2) (BAH domain-containing protein 2) Homo sapiens (Human) NA GO:0003682 3777 XM_029337208.2 5187 2249 2602 5663 5049 Q9P281 2.58e-25 BAH and coiled-coil domain-containing protein 1 (Bromo adjacent homology domain-containing protein 2) (BAH domain-containing protein 2) Homo sapiens (Human) NA GO:0003682 3778 XM_029344298.2 531 687 529 472 742 Q9CQ36 2.28e-22 DNA polymerase epsilon subunit 4 (DNA polymerase II subunit 4) (DNA polymerase epsilon subunit p12) Mus musculus (Mouse) DNA-templated DNA replication [GO:0006261] GO:0003677; GO:0005634; GO:0006261; GO:0008622; GO:0046982; GO:0140672 3779 XR_006393634.1 8 14 8 65 34 NA NA NA NA NA NA 3780 XM_029351214.2 0 1 26 0 63 NA NA NA NA NA NA 3781 XM_044321360.1 55 211 201 180 316 Q96AY4 8.59e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3782 XM_044312040.1 3 0 0 1 18 NA NA NA NA NA NA 3783 XM_029340293.2 505 544 458 541 676 Q5RFD3 7.95e-81 Proteasome activator complex subunit 3 (Activator of multicatalytic protease subunit 3) (Proteasome activator 28 subunit gamma) (PA28g) (PA28gamma) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237] GO:0002039; GO:0005634; GO:0005737; GO:0006915; GO:0007049; GO:0008537; GO:0097371; GO:2001237 3784 XM_029329324.2 165 17 69 91 205 NA NA NA NA NA NA 3785 XM_029331440.2 225 87 173 265 296 NA NA NA NA NA NA 3786 XM_044320627.1 232 154 243 570 319 P35546 1.84e-79 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; anatomical structure morphogenesis [GO:0009653]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006919; GO:0007156; GO:0007158; GO:0007169; GO:0007399; GO:0009410; GO:0009653; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030182; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0098797; GO:2001241 3787 XM_029329341.2 1036 947 485 912 875 Q9CQW0 7e-26 ER membrane protein complex subunit 6 (Transmembrane protein 93) Mus musculus (Mouse) autophagosome assembly [GO:0000045]; protein insertion into ER membrane by stop-transfer membrane-anchor sequence [GO:0045050]; tail-anchored membrane protein insertion into ER membrane [GO:0071816] GO:0000045; GO:0005789; GO:0016020; GO:0032977; GO:0045050; GO:0071816; GO:0072546; GO:1903349 3788 XM_029327547.2 29 9 0 21 0 NA NA NA NA NA NA 3789 XR_006391832.1 2 198 0 463 130 NA NA NA NA NA NA 3790 XM_029358196.2 825 326 334 388 209 O15442 3.68e-84 Metallophosphoesterase domain-containing protein 1 (EC 3.1.-.-) (Adult brain protein 239) (239AB) Homo sapiens (Human) NA GO:0016787 3791 XM_029355788.2 15 13 61 43 59 Q9YGL3 1.39e-93 Nuclear receptor subfamily 2 group E member 1 (Nuclear receptor TLX) (Protein tailless homolog) (Tll) Oryzias latipes (Japanese rice fish) (Japanese killifish) anatomical structure development [GO:0048856]; cell differentiation [GO:0030154]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000978; GO:0004879; GO:0005634; GO:0006357; GO:0008270; GO:0030154; GO:0048856 3792 XM_044310475.1 25 9 12 9 86 NA NA NA NA NA NA 3793 XM_029335917.2 1497 962 1061 2488 1877 A2AHL1 1.81e-166 Anoctamin-3 (Transmembrane protein 16C) Mus musculus (Mouse) calcium activated galactosylceramide scrambling [GO:0061591]; calcium activated phosphatidylcholine scrambling [GO:0061590]; chloride transmembrane transport [GO:1902476]; detection of mechanical stimulus [GO:0050982]; detection of temperature stimulus [GO:0016048]; establishment of localization in cell [GO:0051649]; transmembrane transport [GO:0055085] GO:0005254; GO:0005886; GO:0016048; GO:0017128; GO:0046983; GO:0050982; GO:0051649; GO:0055085; GO:0061590; GO:0061591; GO:1902476 3794 XM_044319982.1 173 89 263 45 46 Q13523 1.44e-179 Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 kinase) (PRP4 pre-mRNA-processing factor 4 homolog) Homo sapiens (Human) mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; protein phosphorylation [GO:0006468]; RNA splicing [GO:0008380] GO:0000398; GO:0003723; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005694; GO:0006468; GO:0008380; GO:0016607; GO:0045292; GO:0071013; GO:0106310 3795 XR_006392412.1 0 1 7 0 0 NA NA NA NA NA NA 3796 XM_029353939.2 53 17 47 80 98 NA NA NA NA NA NA 3797 XM_029323542.2 1104 907 594 576 694 Q8R1N4 2.12e-69 NudC domain-containing protein 3 Mus musculus (Mouse) cilium assembly [GO:0060271]; protein folding [GO:0006457]; protein localization to pericentriolar material [GO:1905793] GO:0005737; GO:0005868; GO:0006457; GO:0051082; GO:0060271; GO:1905793 3798 XM_044324712.1 1493 1307 1195 1331 1394 Q9BX70 0 BTB/POZ domain-containing protein 2 Homo sapiens (Human) neurogenesis [GO:0022008] GO:0000932; GO:0005829; GO:0022008 3799 XM_029342516.2 330 20 274 186 429 NA NA NA NA NA NA 3800 XM_044308795.1 25 0 28 0 0 NA NA NA NA NA NA 3801 XM_029358609.2 1472 731 948 474 2000 Q6P3X3 0 Tetratricopeptide repeat protein 27 (TPR repeat protein 27) Homo sapiens (Human) NA NA 3802 XM_044322180.1 374 295 194 399 479 P21127 0 Cyclin-dependent kinase 11B (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 1) (CLK-1) (Cell division protein kinase 11B) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L1) (p58 CLK-1) Homo sapiens (Human) apoptotic process [GO:0006915]; mitotic cell cycle [GO:0000278]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell growth [GO:0001558]; regulation of centrosome cycle [GO:0046605]; regulation of DNA-templated transcription [GO:0006355]; regulation of mitotic cell cycle [GO:0007346]; regulation of mRNA processing [GO:0050684]; regulation of RNA splicing [GO:0043484] GO:0000278; GO:0000307; GO:0001558; GO:0003723; GO:0004672; GO:0004674; GO:0004693; GO:0005524; GO:0005634; GO:0005737; GO:0006355; GO:0006468; GO:0006915; GO:0007346; GO:0042981; GO:0043484; GO:0046605; GO:0050684; GO:0051726; GO:0106310 3803 XM_029332705.2 433 316 297 500 357 NA NA NA NA NA NA 3804 XM_029325598.2 2140 975 429 1689 1324 NA NA NA NA NA NA 3805 XM_029349578.2 611 466 331 516 322 Q9QZU7 3.99e-86 Gamma-butyrobetaine dioxygenase (EC 1.14.11.1) (Gamma-butyrobetaine hydroxylase) (Gamma-BBH) (Gamma-butyrobetaine,2-oxoglutarate dioxygenase) Rattus norvegicus (Rat) carnitine biosynthetic process [GO:0045329] GO:0005506; GO:0005739; GO:0008270; GO:0008336; GO:0042802; GO:0045329 3806 XR_006391363.1 177 29 118 277 68 O15160 6.39e-115 DNA-directed RNA polymerases I and III subunit RPAC1 (DNA-directed RNA polymerase I subunit C) (RNA polymerases I and III subunit AC1) (AC40) (DNA-directed RNA polymerases I and III 40 kDa polypeptide) (RPA40) (RPA39) (RPC40) Homo sapiens (Human) transcription by RNA polymerase I [GO:0006360] GO:0001054; GO:0001056; GO:0001650; GO:0003677; GO:0003899; GO:0005654; GO:0005666; GO:0005736; GO:0005829; GO:0006360; GO:0046983 3807 XM_029326199.2 24 6 27 0 51 NA NA NA NA NA NA 3808 XM_044312606.1 32 64 50 251 0 NA NA NA NA NA NA 3809 XM_044308010.1 285 16 63 100 245 NA NA NA NA NA NA 3810 XM_044327945.1 255 68 30 85 60 NA NA NA NA NA NA 3811 XM_044307111.1 772 65 8 63 10 Q9U6Y6 8.19e-109 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 3812 XM_044312795.1 627 511 298 525 357 Q7ZU45 3.78e-163 Outer dynein arm-docking complex subunit 4 (Tetratricopeptide repeat protein 25) (TPR repeat protein 25) Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of heart left/right asymmetry [GO:0061371]; otolith morphogenesis [GO:0032474]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0005737; GO:0005856; GO:0032474; GO:0036158; GO:0042995; GO:0060271; GO:0061371 3813 XM_044317251.1 55 11 28 35 12 NA NA NA NA NA NA 3814 XM_044325953.1 0 0 47 0 23 NA NA NA NA NA NA 3815 XM_044309126.1 73 0 0 54 73 C3YZ51 8.96e-173 Ubiquitin-like modifier-activating enzyme 5 (Ubiquitin-activating enzyme 5) Branchiostoma floridae (Florida lancelet) (Amphioxus) protein modification by small protein conjugation [GO:0032446]; protein ufmylation [GO:0071569] GO:0005524; GO:0005737; GO:0005829; GO:0032446; GO:0046872; GO:0071566; GO:0071569 3816 XM_044320490.1 271 128 64 207 128 NA NA NA NA NA NA 3817 XR_006395286.1 22 15 15 12 15 NA NA NA NA NA NA 3818 XM_044324001.1 22 17 0 7 4 Q805E5 9.69e-40 Carbohydrate sulfotransferase 14 (EC 2.8.2.-) (Dermatan 4-sulfotransferase 1) (D4ST-1) (zD4ST-1) Danio rerio (Zebrafish) (Brachydanio rerio) carbohydrate biosynthetic process [GO:0016051]; dermatan sulfate proteoglycan metabolic process [GO:0050655] GO:0000139; GO:0001537; GO:0008146; GO:0016051; GO:0050655 3819 XM_029324617.2 3836 2195 1650 3424 3463 Q4KM31 2.31e-33 LIM domain-containing protein 2 Rattus norvegicus (Rat) NA GO:0005634; GO:0005737; GO:0046872 3820 XM_029358443.2 0 0 0 14 0 Q6ZSM3 2.23e-24 Monocarboxylate transporter 12 (MCT 12) (Creatine transporter 2) (CRT2) (Solute carrier family 16 member 12) Homo sapiens (Human) creatine transmembrane transport [GO:0015881]; creatinine metabolic process [GO:0046449]; monocarboxylic acid transport [GO:0015718]; transport across blood-brain barrier [GO:0150104] GO:0005308; GO:0005886; GO:0008028; GO:0015292; GO:0015718; GO:0015881; GO:0016020; GO:0016323; GO:0046449; GO:0150104 3821 XR_006397480.1 330 1674 818 2529 1179 NA NA NA NA NA NA 3822 XM_029331113.2 2219 1593 1405 1966 1717 Q9UDY8 1.63e-35 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (EC 3.4.22.-) (MALT lymphoma-associated translocation) (Paracaspase) Homo sapiens (Human) activation of NF-kappaB-inducing kinase activity [GO:0007250]; B cell activation [GO:0042113]; B-1 B cell differentiation [GO:0001923]; defense response [GO:0006952]; innate immune response [GO:0045087]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; negative regulation of apoptotic process [GO:0043066]; nuclear export [GO:0051168]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T-helper 17 cell differentiation [GO:2000321]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of apoptotic process [GO:0042981]; regulation of T cell receptor signaling pathway [GO:0050856]; response to fungus [GO:0009620]; T cell proliferation [GO:0042098]; T cell receptor signaling pathway [GO:0050852] GO:0001650; GO:0001923; GO:0002020; GO:0002096; GO:0002726; GO:0004175; GO:0004197; GO:0004842; GO:0005634; GO:0005737; GO:0005829; GO:0006508; GO:0006952; GO:0007250; GO:0008233; GO:0009620; GO:0031398; GO:0031663; GO:0032449; GO:0032731; GO:0032743; GO:0032991; GO:0036094; GO:0042098; GO:0042113; GO:0042802; GO:0042981; GO:0043066; GO:0043123; GO:0043280; GO:0043621; GO:0045087; GO:0048471; GO:0050852; GO:0050856; GO:0051092; GO:0051168; GO:0051603; GO:2000321 3823 XM_044315914.1 16 0 0 7 19 NA NA NA NA NA NA 3824 XM_044319979.1 3274 1895 1839 3076 2762 Q3UMR0 0 Ankyrin repeat domain-containing protein 27 (VPS9 domain-containing protein) (VPS9-ankyrin-repeat protein) Mus musculus (Mouse) early endosome to late endosome transport [GO:0045022]; endocytic recycling [GO:0032456]; endosome to melanosome transport [GO:0035646]; negative regulation of SNARE complex assembly [GO:0035544]; neuron projection morphogenesis [GO:0048812]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of neuron projection development [GO:0010976]; protein transport [GO:0015031] GO:0000149; GO:0005085; GO:0005096; GO:0005764; GO:0005769; GO:0005770; GO:0005829; GO:0005886; GO:0010976; GO:0015031; GO:0030133; GO:0030659; GO:0031267; GO:0032456; GO:0035544; GO:0035646; GO:0042470; GO:0043005; GO:0043231; GO:0045022; GO:0048812; GO:0050775; GO:0097422 3825 XM_029352940.2 1794 644 643 707 1047 Q99LB6 2.55e-99 Methionine adenosyltransferase 2 subunit beta (Methionine adenosyltransferase II beta) (MAT II beta) Mus musculus (Mouse) one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556] GO:0005634; GO:0005739; GO:0006556; GO:0006730; GO:0019899; GO:0048269; GO:0048270 3826 XM_029340760.2 0 0 291 0 0 P21674 8.26e-38 Follistatin (FS) (Activin-binding protein) Rattus norvegicus (Rat) ameloblast differentiation [GO:0036305]; BMP signaling pathway [GO:0030509]; cell differentiation [GO:0030154]; cellular response to growth factor stimulus [GO:0071363]; female gonad development [GO:0008585]; gamete generation [GO:0007276]; hair follicle morphogenesis [GO:0031069]; hematopoietic progenitor cell differentiation [GO:0002244]; keratinocyte proliferation [GO:0043616]; negative regulation of activin receptor signaling pathway [GO:0032926]; negative regulation of cell differentiation [GO:0045596]; negative regulation of epithelial cell differentiation [GO:0030857]; negative regulation of follicle-stimulating hormone secretion [GO:0046882]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis of dentin-containing tooth [GO:0042475]; pattern specification process [GO:0007389]; positive regulation of hair follicle development [GO:0051798]; regulation of BMP signaling pathway [GO:0030510]; response to organic cyclic compound [GO:0014070]; skeletal system development [GO:0001501] GO:0000122; GO:0001501; GO:0002244; GO:0005615; GO:0005634; GO:0005737; GO:0007276; GO:0007389; GO:0008585; GO:0014070; GO:0030154; GO:0030509; GO:0030510; GO:0030857; GO:0031069; GO:0032926; GO:0036305; GO:0038102; GO:0042475; GO:0043395; GO:0043616; GO:0045596; GO:0046882; GO:0048185; GO:0051798; GO:0071363 3827 XM_029339210.2 199 126 116 304 242 Q5F4B8 2.45e-41 Solute carrier family 46 member 3 Gallus gallus (Chicken) transmembrane transport [GO:0055085]; vacuolar transmembrane transport [GO:0034486] GO:0005765; GO:0016020; GO:0022857; GO:0034486; GO:0055085 3828 XM_029357859.2 9 0 8 10 19 NA NA NA NA NA NA 3829 XM_029351108.2 8 0 0 1 0 NA NA NA NA NA NA 3830 XM_044328439.1 57 0 29 11 8 NA NA NA NA NA NA 3831 XM_029348634.2 1881 1507 941 2078 1765 Q9VDG5 9.55e-123 NA NA NA NA 3832 XM_029334306.2 383 195 227 340 379 NA NA NA NA NA NA 3833 XM_029338053.2 1791 1679 657 1450 945 Q5E964 6.05e-145 26S proteasome non-ATPase regulatory subunit 13 (26S proteasome regulatory subunit RPN9) (26S proteasome regulatory subunit S11) (26S proteasome regulatory subunit p40.5) Bos taurus (Bovine) meiosis I [GO:0007127]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0005198; GO:0005634; GO:0005829; GO:0006511; GO:0007127; GO:0008541; GO:0022624 3834 XM_044314428.1 40 20 0 7 18 NA NA NA NA NA NA 3835 XM_029339083.2 2107 1080 964 1992 1724 Q7ZUA6 1.91e-126 Limb region 1 protein homolog Gallus gallus (Chicken) signal transduction [GO:0007165] GO:0004888; GO:0005886; GO:0007165 3836 XM_044319805.1 198 93 11 72 178 NA NA NA NA NA NA 3837 XM_029347892.2 329 249 141 263 50 NA NA NA NA NA NA 3838 XR_006395091.1 862 560 368 607 378 NA NA NA NA NA NA 3839 XM_044306800.1 0 0 0 9 0 NA NA NA NA NA NA 3840 XM_044306929.1 0 0 90 0 186 Q8IVE3 0 Pleckstrin homology domain-containing family H member 2 Homo sapiens (Human) negative regulation of actin filament depolymerization [GO:0030835] GO:0003779; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0016604; GO:0030027; GO:0030835; GO:0030864 3841 XM_044327925.1 0 0 0 27 14 NA NA NA NA NA NA 3842 XM_029341141.2 134 0 21 0 73 NA NA NA NA NA NA 3843 XM_029328605.2 990 113 648 324 558 Q8R3F5 3.88e-48 Malonyl-CoA-acyl carrier protein transacylase, mitochondrial (MCT) (EC 2.3.1.39) (Mitochondrial malonyltransferase) ([Acyl-carrier-protein] malonyltransferase) Mus musculus (Mouse) fatty acid biosynthetic process [GO:0006633] GO:0004312; GO:0004314; GO:0005739; GO:0006633 3844 XM_029348807.2 75 18 46 48 86 NA NA NA NA NA NA 3845 XM_029347827.2 33 6 23 9 14 NA NA NA NA NA NA 3846 XM_044317975.1 1833 1476 923 1868 991 Q7TQH0 4.07e-28 Ataxin-2-like protein Mus musculus (Mouse) mRNA metabolic process [GO:0016071]; stress granule assembly [GO:0034063] GO:0003723; GO:0005829; GO:0010494; GO:0016020; GO:0016071; GO:0016607; GO:0034063 3847 XM_029334044.2 89 19 16 29 179 Q00168 3.41e-59 Calcium/calmodulin-dependent protein kinase type II alpha chain (CaM-kinase II alpha chain) (EC 2.7.11.17) Drosophila melanogaster (Fruit fly) cellular response to starvation [GO:0009267]; chemical synaptic transmission [GO:0007268]; courtship behavior [GO:0007619]; learning or memory [GO:0007611]; long-term memory [GO:0007616]; male courtship behavior [GO:0008049]; negative regulation of cytokine production [GO:0001818]; negative regulation of lipid storage [GO:0010888]; neuromuscular junction development [GO:0007528]; peptidyl-threonine autophosphorylation [GO:1990443]; positive regulation of synaptic transmission, dopaminergic [GO:0032226]; protein phosphorylation [GO:0006468]; regulation of filopodium assembly [GO:0051489]; regulation of ovulation [GO:0060278]; regulation of synaptic assembly at neuromuscular junction [GO:0008582] GO:0001818; GO:0004674; GO:0004683; GO:0005516; GO:0005524; GO:0005737; GO:0006468; GO:0007268; GO:0007528; GO:0007611; GO:0007616; GO:0007619; GO:0008049; GO:0008582; GO:0009267; GO:0010888; GO:0030424; GO:0030425; GO:0032226; GO:0043005; GO:0045211; GO:0048786; GO:0051489; GO:0060278; GO:0106310; GO:1990443 3848 XM_044309122.1 292 290 193 342 572 Q9Z0W3 1.04e-180 Nuclear pore complex protein Nup160 (160 kDa nucleoporin) (Gene trap locus 1-13 protein) (GTL-13) (Nucleoporin Nup160) Mus musculus (Mouse) mRNA export from nucleus [GO:0006406]; nephron development [GO:0072006]; nucleocytoplasmic transport [GO:0006913]; protein transport [GO:0015031] GO:0000776; GO:0005635; GO:0005643; GO:0006406; GO:0006913; GO:0015031; GO:0017056; GO:0031080; GO:0072006 3849 XM_044315449.1 133 66 44 0 0 NA NA NA NA NA NA 3850 XM_044325140.1 51 47 69 72 65 NA NA NA NA NA NA 3851 XR_006395976.1 142 101 105 82 149 NA NA NA NA NA NA 3852 XM_044324324.1 2635 1422 1398 2045 1707 Q9CW42 1.05e-45 Mitochondrial amidoxime-reducing component 1 (mARC1) (EC 1.7.-.-) (Molybdenum cofactor sulfurase C-terminal domain-containing protein 1) (MOSC domain-containing protein 1) (Moco sulfurase C-terminal domain-containing protein 1) Mus musculus (Mouse) cellular detoxification of nitrogen compound [GO:0070458]; nitrate metabolic process [GO:0042126]; nitric oxide biosynthetic process [GO:0006809] GO:0005739; GO:0005741; GO:0005743; GO:0006809; GO:0008940; GO:0016661; GO:0030151; GO:0030170; GO:0042126; GO:0043546; GO:0050421; GO:0070458; GO:0098809; GO:1903958 3853 XM_044322341.1 0 0 4 7 8 NA NA NA NA NA NA 3854 XM_044320482.1 1597 1171 691 1261 1331 O95140 0 Mitofusin-2 (EC 3.6.5.-) (Transmembrane GTPase MFN2) Homo sapiens (Human) apoptotic process [GO:0006915]; blastocyst formation [GO:0001825]; camera-type eye morphogenesis [GO:0048593]; mitochondrial fusion [GO:0008053]; mitochondrial membrane organization [GO:0007006]; mitochondrion localization [GO:0051646]; negative regulation of Ras protein signal transduction [GO:0046580]; negative regulation of smooth muscle cell proliferation [GO:0048662]; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:0061734]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular associated smooth muscle cell proliferation [GO:1904707]; protein localization to phagophore assembly site [GO:0034497]; protein targeting to mitochondrion [GO:0006626]; response to unfolded protein [GO:0006986] GO:0001825; GO:0003924; GO:0005525; GO:0005739; GO:0005741; GO:0005829; GO:0006626; GO:0006915; GO:0006986; GO:0007006; GO:0008053; GO:0015630; GO:0031625; GO:0034497; GO:0046580; GO:0048593; GO:0048662; GO:0051646; GO:0061734; GO:0120162; GO:1904707; GO:1905461 3855 XM_044309106.1 31 15 8 105 27 NA NA NA NA NA NA 3856 XM_044311798.1 37 17 0 2 75 NA NA NA NA NA NA 3857 XM_029356941.2 6220 5510 3592 6160 5086 H9BW96 5.32e-132 Ras-related protein rab7 Epinephelus coioides (Orange-spotted grouper) (Epinephelus nebulosus) early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; lipid catabolic process [GO:0016042]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of viral process [GO:0048524]; protein targeting to lysosome [GO:0006622] GO:0003924; GO:0005525; GO:0005765; GO:0005770; GO:0005829; GO:0006622; GO:0008333; GO:0010008; GO:0016042; GO:0031902; GO:0045022; GO:0045732; GO:0048524 3858 XM_044310893.1 660 670 233 692 302 P81274 7.61e-64 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 3859 XM_044310893.1 660 670 233 692 302 P81274 3.22e-59 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 3860 XM_044310893.1 660 670 233 692 302 P81274 1.66e-44 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 3861 XM_044310893.1 660 670 233 692 302 P81274 1.05e-32 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 3862 XM_044326301.1 372 318 174 236 363 Q5XGL1 2.9e-23 Centromere protein K (CENP-K) Xenopus laevis (African clawed frog) kinetochore assembly [GO:0051382] GO:0000776; GO:0005634; GO:0051382 3863 XM_044311689.1 5 0 15 0 0 Q09575 8.72e-34 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 3864 XM_044314651.1 36 7 21 22 48 NA NA NA NA NA NA 3865 XM_029353672.2 211 8 5 18 446 NA NA NA NA NA NA 3866 XM_044324637.1 6 0 0 0 4 NA NA NA NA NA NA 3867 XM_029332577.2 96 60 69 97 189 NA NA NA NA NA NA 3868 XM_029346323.2 265 265 130 274 126 O00305 2.12e-63 Voltage-dependent L-type calcium channel subunit beta-4 (CAB4) (Calcium channel voltage-dependent subunit beta 4) Homo sapiens (Human) adult walking behavior [GO:0007628]; cAMP metabolic process [GO:0046058]; cellular response to leukemia inhibitory factor [GO:1990830]; chemical synaptic transmission [GO:0007268]; detection of light stimulus involved in visual perception [GO:0050908]; gamma-aminobutyric acid secretion [GO:0014051]; gamma-aminobutyric acid signaling pathway [GO:0007214]; muscle cell development [GO:0055001]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; neuromuscular junction development [GO:0007528]; neuronal action potential propagation [GO:0019227]; Peyer's patch development [GO:0048541]; positive regulation of protein localization to nucleolus [GO:1904751]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; regulation of synaptic vesicle exocytosis [GO:2000300]; regulation of voltage-gated calcium channel activity [GO:1901385]; spleen development [GO:0048536]; synaptic transmission, glutamatergic [GO:0035249]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538] GO:0005730; GO:0005829; GO:0005886; GO:0005891; GO:0007214; GO:0007268; GO:0007528; GO:0007628; GO:0008285; GO:0009898; GO:0014051; GO:0016607; GO:0019227; GO:0019901; GO:0035249; GO:0045202; GO:0046058; GO:0048536; GO:0048538; GO:0048541; GO:0050852; GO:0050908; GO:0055001; GO:0098793; GO:0098978; GO:0099626; GO:1901385; GO:1901387; GO:1904751; GO:1990830; GO:2000134; GO:2000300 3869 XM_029347132.2 1929 1220 1156 938 1514 P12890 7.5e-168 Peptidyl-glycine alpha-amidating monooxygenase B (PAM-B) (Peptide C-terminal alpha-amidating enzyme II) (AE-II) (Peptidyl-glycine alpha-amidating monooxygenase II) [Includes: Peptidylglycine alpha-hydroxylating monooxygenase B (PHM-B) (EC 1.14.17.3); Peptidyl-alpha-hydroxyglycine alpha-amidating lyase B (EC 4.3.2.5) (Peptidylamidoglycolate lyase-B) (PAL-B)] Xenopus laevis (African clawed frog) peptide metabolic process [GO:0006518] GO:0004504; GO:0004598; GO:0005507; GO:0006518; GO:0030658 3870 XM_029330352.2 524 381 295 470 861 P08397 3.22e-113 Porphobilinogen deaminase (PBG-D) (EC 2.5.1.61) (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Homo sapiens (Human) heme biosynthetic process [GO:0006783]; peptidyl-pyrromethane cofactor linkage [GO:0018160]; protoporphyrinogen IX biosynthetic process [GO:0006782] GO:0004418; GO:0005737; GO:0005829; GO:0006782; GO:0006783; GO:0018160 3871 XM_029355681.2 0 0 0 0 536 NA NA NA NA NA NA 3872 XM_029348958.2 423 169 24 131 223 Q8BVQ5 1.42e-122 Protein phosphatase methylesterase 1 (PME-1) (EC 3.1.1.89) Mus musculus (Mouse) protein demethylation [GO:0006482]; protein phosphorylation [GO:0006468] GO:0006468; GO:0006482; GO:0019901; GO:0019903; GO:0051721; GO:0051722; GO:0051723; GO:0106222 3873 XM_029343599.2 110 199 157 175 253 NA NA NA NA NA NA 3874 XM_044326908.1 915 727 713 621 922 NA NA NA NA NA NA 3875 XM_029335419.2 1542 1739 1082 1257 1287 B6NXD5 2.4e-108 BRISC and BRCA1-A complex member 2 (BRCA1-A complex subunit BRE) (BRCA1/BRCA2-containing complex subunit 45) (Brain and reproductive organ-expressed protein) Branchiostoma floridae (Florida lancelet) (Amphioxus) apoptotic process [GO:0006915]; cell division [GO:0051301]; chromatin organization [GO:0006325]; double-strand break repair [GO:0006302]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; positive regulation of DNA repair [GO:0045739]; response to ionizing radiation [GO:0010212] GO:0005634; GO:0005737; GO:0006302; GO:0006325; GO:0006915; GO:0007095; GO:0010212; GO:0031593; GO:0045739; GO:0051301; GO:0070531; GO:0070552 3876 XM_029327025.2 10 27 40 18 93 NA NA NA NA NA NA 3877 XM_029355502.2 443 306 324 386 416 Q8BH18 2.55e-142 Transmembrane protein 117 Mus musculus (Mouse) intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059] GO:0005783; GO:0005886; GO:0070059 3878 XM_029335262.2 2961 1514 1588 3825 3964 Q8JFV8 7.11e-122 Synaptic vesicle membrane protein VAT-1 homolog (EC 1.-.-.-) Danio rerio (Zebrafish) (Brachydanio rerio) negative regulation of mitochondrial fusion [GO:0010637] GO:0005741; GO:0008270; GO:0010637; GO:0016491 3879 XM_029337849.2 36 28 16 23 21 NA NA NA NA NA NA 3880 XM_044318591.1 2713 1846 1294 1771 620 Q9D6Y9 0 1,4-alpha-glucan-branching enzyme (EC 2.4.1.18) (Brancher enzyme) (Glycogen-branching enzyme) Mus musculus (Mouse) carbohydrate metabolic process [GO:0005975]; glycogen biosynthetic process [GO:0005978]; negative regulation of neuron apoptotic process [GO:0043524] GO:0003844; GO:0004553; GO:0005737; GO:0005829; GO:0005975; GO:0005978; GO:0030246; GO:0043169; GO:0043524; GO:0102752 3881 XM_044308042.1 621 684 599 856 959 Q66KA5 1.1e-64 Protein YIPF5 (YIP1 family member 5) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; protein transport [GO:0015031] GO:0005789; GO:0005794; GO:0006888; GO:0015031 3882 XR_006394252.1 4583 12136 7240 10719 28336 NA NA NA NA NA NA 3883 XR_006392667.1 17 13 22 16 105 NA NA NA NA NA NA 3884 XM_029357428.2 190 256 155 253 189 P48547 1.37e-93 Potassium voltage-gated channel subfamily C member 1 (NGK2) (Voltage-gated potassium channel subunit Kv3.1) (Voltage-gated potassium channel subunit Kv4) Homo sapiens (Human) cellular response to xenobiotic stimulus [GO:0071466]; cerebellum development [GO:0021549]; corpus callosum development [GO:0022038]; globus pallidus development [GO:0021759]; optic nerve development [GO:0021554]; positive regulation of voltage-gated potassium channel activity [GO:1903818]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; protein tetramerization [GO:0051262]; response to amine [GO:0014075]; response to auditory stimulus [GO:0010996]; response to fibroblast growth factor [GO:0071774]; response to light intensity [GO:0009642]; response to nerve growth factor [GO:1990089]; response to potassium ion [GO:0035864]; response to toxic substance [GO:0009636] GO:0005249; GO:0005251; GO:0005886; GO:0006813; GO:0008076; GO:0009636; GO:0009642; GO:0009986; GO:0010996; GO:0014075; GO:0016020; GO:0019894; GO:0021549; GO:0021554; GO:0021759; GO:0022038; GO:0030424; GO:0030673; GO:0032590; GO:0032809; GO:0035864; GO:0042734; GO:0044305; GO:0044325; GO:0045211; GO:0051260; GO:0051262; GO:0071466; GO:0071774; GO:0071805; GO:0099508; GO:1903818; GO:1990089 3885 XR_006391285.1 64 31 17 53 101 NA NA NA NA NA NA 3886 XR_006392765.1 100 84 106 71 369 NA NA NA NA NA NA 3887 XM_044323660.1 10 3 0 0 4 NA NA NA NA NA NA 3888 XM_029338887.2 1575 2597 3191 2713 2789 NA NA NA NA NA NA 3889 XM_029343771.2 193 372 112 184 147 NA NA NA NA NA NA 3890 XM_044325791.1 0 9 0 20 23 NA NA NA NA NA NA 3891 XM_029351733.2 0 3 83 0 0 NA NA NA NA NA NA 3892 XM_044313056.1 67 9 9 26 25 Q96AY4 2.84e-81 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3893 XM_044313056.1 67 9 9 26 25 Q96AY4 7.27e-80 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3894 XM_044313056.1 67 9 9 26 25 Q96AY4 5.13e-79 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3895 XM_044313056.1 67 9 9 26 25 Q96AY4 1.45e-77 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3896 XM_044313056.1 67 9 9 26 25 Q96AY4 2.44e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3897 XM_044313056.1 67 9 9 26 25 Q96AY4 2.54e-71 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3898 XM_044313056.1 67 9 9 26 25 Q96AY4 1.79e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3899 XM_044313056.1 67 9 9 26 25 Q96AY4 1.03e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3900 XM_029340401.2 281 270 160 205 171 NA NA NA NA NA NA 3901 XM_029345483.2 727 113 192 48 130 NA NA NA NA NA NA 3902 XM_029331506.2 11 17 13 13 8 B8VIU6 4.15e-46 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 3903 XM_029331881.2 155 13 148 109 183 NA NA NA NA NA NA 3904 XM_029336531.2 1088 904 530 855 612 NA NA NA NA NA NA 3905 XM_044327603.1 70 0 0 0 1 NA NA NA NA NA NA 3906 XR_006395028.1 2 2 1 7 0 NA NA NA NA NA NA 3907 XM_044310823.1 2 5 0 18 2 NA NA NA NA NA NA 3908 XM_044323566.1 5 8 26 14 80 NA NA NA NA NA NA 3909 XM_044313870.1 258 305 133 302 271 A0A2P1BRQ0 6.87e-85 Cytolytic toxin-alpha (Sp-CTx-alpha) Scorpaena plumieri (Spotted scorpionfish) hemolysis in another organism [GO:0044179] GO:0005576; GO:0044179; GO:0090729 3910 XR_006397415.1 8 5 11 0 28 NA NA NA NA NA NA 3911 XM_029341437.2 0 90 0 95 0 NA NA NA NA NA NA 3912 XM_044306972.1 0 324 0 72 0 A6PWV5 3.32e-67 AT-rich interactive domain-containing protein 3C (ARID domain-containing protein 3C) Mus musculus (Mouse) positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0003677; GO:0003682; GO:0005634; GO:0005737; GO:0006357; GO:0045121; GO:0045944 3913 XM_029345468.2 0 0 23 0 44 Q8N2E2 1.47e-39 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 3914 XM_029345468.2 0 0 23 0 44 Q8N2E2 8.92e-38 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 3915 XM_029345468.2 0 0 23 0 44 Q8N2E2 1.59e-36 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 3916 XM_029345468.2 0 0 23 0 44 Q8N2E2 4.97e-35 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 3917 XM_029345468.2 0 0 23 0 44 Q8N2E2 5.87e-32 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 3918 XM_029345468.2 0 0 23 0 44 Q8N2E2 4.31e-25 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 3919 XM_044310319.1 395 159 153 217 154 Q9NR20 2.28e-66 Dual specificity tyrosine-phosphorylation-regulated kinase 4 (EC 2.7.12.1) Homo sapiens (Human) peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107] GO:0004674; GO:0004712; GO:0004713; GO:0005524; GO:0005634; GO:0005737; GO:0005856; GO:0018105; GO:0018107; GO:0043231; GO:0046872; GO:0106310 3920 XM_044325929.1 1266 156 271 517 397 NA NA NA NA NA NA 3921 XM_044324718.1 541 202 75 248 251 Q1L8I0 9.22e-105 Pseudouridylate synthase PUS7L (EC 5.4.99.-) (Pseudouridylate synthase 7 homolog-like protein) Danio rerio (Zebrafish) (Brachydanio rerio) mRNA processing [GO:0006397]; mRNA pseudouridine synthesis [GO:1990481]; pseudouridine synthesis [GO:0001522] GO:0001522; GO:0003723; GO:0005634; GO:0006397; GO:0009982; GO:1990481 3922 XM_044311958.1 45 2 24 24 63 Q76KP1 2.3e-32 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Homo sapiens (Human) NA GO:0008376; GO:0032580; GO:0033842 3923 XM_044325303.1 24 20 9 6 33 NA NA NA NA NA NA 3924 XM_029342242.2 0 0 0 234 106 O88898 6.36e-58 Tumor protein 63 (p63) (Transformation-related protein 63) (TP63) (Tumor protein p73-like) (p73L) Mus musculus (Mouse) anatomical structure formation involved in morphogenesis [GO:0048646]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular senescence [GO:0090398]; chromatin remodeling [GO:0006338]; cloacal septation [GO:0060197]; cranial skeletal system development [GO:1904888]; ectoderm and mesoderm interaction [GO:0007499]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; epidermal cell differentiation [GO:0009913]; epidermal cell division [GO:0010481]; epidermis development [GO:0008544]; epithelial cell development [GO:0002064]; epithelial cell differentiation [GO:0030855]; establishment of planar polarity [GO:0001736]; establishment of skin barrier [GO:0061436]; female genitalia morphogenesis [GO:0048807]; hair follicle development [GO:0001942]; hair follicle morphogenesis [GO:0031069]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; keratinocyte differentiation [GO:0030216]; keratinocyte proliferation [GO:0043616]; morphogenesis of a polarized epithelium [GO:0001738]; multicellular organism aging [GO:0010259]; negative regulation of cellular senescence [GO:2000773]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of keratinocyte differentiation [GO:0045617]; negative regulation of mesoderm development [GO:2000381]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron apoptotic process [GO:0051402]; Notch signaling pathway [GO:0007219]; odontogenesis of dentin-containing tooth [GO:0042475]; pattern specification process [GO:0007389]; polarized epithelial cell differentiation [GO:0030859]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cell cycle G1/S phase transition [GO:1902808]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of fibroblast apoptotic process [GO:2000271]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of somatic stem cell population maintenance [GO:1904674]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; prostate gland development [GO:0030850]; prostatic bud formation [GO:0060513]; protein tetramerization [GO:0051262]; proximal/distal pattern formation [GO:0009954]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of epidermal cell division [GO:0010482]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal system development [GO:0001501]; skin epidermis development [GO:0098773]; skin morphogenesis [GO:0043589]; spermatogenesis [GO:0007283]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; stem cell differentiation [GO:0048863]; stem cell proliferation [GO:0072089]; sympathetic nervous system development [GO:0048485]; transcription by RNA polymerase II [GO:0006366] GO:0000122; GO:0000785; GO:0000977; GO:0000978; GO:0000981; GO:0001228; GO:0001501; GO:0001736; GO:0001738; GO:0001942; GO:0002039; GO:0002064; GO:0003677; GO:0003682; GO:0003684; GO:0003690; GO:0003700; GO:0005634; GO:0005654; GO:0005737; GO:0005791; GO:0006338; GO:0006357; GO:0006366; GO:0006915; GO:0006974; GO:0007219; GO:0007283; GO:0007389; GO:0007499; GO:0008284; GO:0008544; GO:0009887; GO:0009913; GO:0009954; GO:0010259; GO:0010481; GO:0010482; GO:0010838; GO:0019904; GO:0030216; GO:0030326; GO:0030425; GO:0030850; GO:0030855; GO:0030859; GO:0031069; GO:0032991; GO:0033147; GO:0035115; GO:0035116; GO:0036342; GO:0042475; GO:0042771; GO:0042802; GO:0043005; GO:0043281; GO:0043565; GO:0043589; GO:0043616; GO:0045617; GO:0045669; GO:0045747; GO:0045892; GO:0045893; GO:0045944; GO:0046872; GO:0048485; GO:0048646; GO:0048807; GO:0048863; GO:0050699; GO:0051262; GO:0051402; GO:0060197; GO:0060513; GO:0060529; GO:0061436; GO:0072089; GO:0090398; GO:0097371; GO:0098773; GO:1902808; GO:1904674; GO:1904888; GO:2000271; GO:2000381; GO:2000648; GO:2000773; GO:2001235 3925 XM_044324260.1 337 24 0 0 0 P07949 6.41e-76 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; axon guidance [GO:0007411]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; lymphocyte migration into lymphoid organs [GO:0097021]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; posterior midgut development [GO:0007497]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006468; GO:0006919; GO:0007156; GO:0007158; GO:0007165; GO:0007169; GO:0007411; GO:0007497; GO:0009410; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0038023; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0097021; GO:0098797; GO:2001241 3926 XM_029346051.2 20 5 2 32 8 Q7TN88 4.87e-58 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 3927 XM_029346051.2 20 5 2 32 8 Q7TN88 5.32e-36 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 3928 XM_029334876.2 1296 700 714 849 964 A1DWM3 8.42e-29 Major facilitator superfamily domain-containing protein 6 (Macrophage MHC class I receptor 2 homolog) Sus scrofa (Pig) antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590] GO:0005886; GO:0016020; GO:0042590 3929 XM_044322793.1 21 46 0 14 5 NA NA NA NA NA NA 3930 XM_044317718.1 224 214 275 150 85 Q502P0 1.14e-21 ADP-ribosylation factor-like protein 6-interacting protein 4 (ARL-6-interacting protein 4) (Aip-4) Danio rerio (Zebrafish) (Brachydanio rerio) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0005730; GO:0006397; GO:0008380; GO:0016607 3931 XR_006397242.1 884 156 0 39 202 NA NA NA NA NA NA 3932 XM_029339045.2 370 218 153 287 237 Q13889 5.48e-106 General transcription factor IIH subunit 3 (Basic transcription factor 2 34 kDa subunit) (BTF2 p34) (General transcription factor IIH polypeptide 3) (TFIIH basal transcription factor complex p34 subunit) Homo sapiens (Human) DNA repair [GO:0006281]; nucleotide-excision repair [GO:0006289]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; transcription by RNA polymerase II [GO:0006366] GO:0000438; GO:0000439; GO:0005634; GO:0005654; GO:0005669; GO:0005675; GO:0006281; GO:0006289; GO:0006366; GO:0016251; GO:0046872; GO:0047485; GO:0070816; GO:0097550 3933 XM_029347271.2 85 344 869 1372 834 NA NA NA NA NA NA 3934 XM_029340285.1 3470 2560 2157 2389 3198 P11233 2.71e-88 Ras-related protein Ral-A (EC 3.6.5.2) Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; cell cycle [GO:0007049]; cell division [GO:0051301]; chemotaxis [GO:0006935]; establishment of protein localization to mitochondrion [GO:0072655]; exocytosis [GO:0006887]; membrane raft localization [GO:0051665]; neural tube closure [GO:0001843]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of mitochondrial fission [GO:0090141]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of exocytosis [GO:0017157]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; signal transduction [GO:0007165] GO:0001843; GO:0003924; GO:0003925; GO:0005525; GO:0005739; GO:0005886; GO:0005925; GO:0006887; GO:0006935; GO:0007049; GO:0007165; GO:0007265; GO:0009986; GO:0017022; GO:0017157; GO:0019003; GO:0030659; GO:0031532; GO:0031623; GO:0031625; GO:0031755; GO:0032154; GO:0045742; GO:0051117; GO:0051301; GO:0051491; GO:0051665; GO:0070062; GO:0072655; GO:0090141; GO:0090543; GO:0097060; GO:0098685; GO:0099149 3935 XR_006394455.1 825 639 4293 3071 7491 NA NA NA NA NA NA 3936 XM_029324649.2 61 50 68 64 102 B0UYT5 7.04e-29 Major facilitator superfamily domain-containing protein 6-B (Macrophage MHC class I receptor 2 homolog B) Danio rerio (Zebrafish) (Brachydanio rerio) antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590] GO:0005886; GO:0016020; GO:0042590 3937 XM_044322369.1 579 331 145 638 352 NA NA NA NA NA NA 3938 XR_006393024.1 245 259 108 40 278 NA NA NA NA NA NA 3939 XR_003825338.2 11 0 13 14 32 NA NA NA NA NA NA 3940 XR_006391631.1 2 5 16 3 8 NA NA NA NA NA NA 3941 XR_006395856.1 659 565 649 1584 1391 NA NA NA NA NA NA 3942 XM_029357999.2 171 119 121 44 124 NA NA NA NA NA NA 3943 XR_006397054.1 2 0 0 0 7 NA NA NA NA NA NA 3944 XM_044325205.1 31 52 19 19 20 NA NA NA NA NA NA 3945 XM_044311071.1 220 8 85 51 74 NA NA NA NA NA NA 3946 XM_044311726.1 445 380 93 448 343 NA NA NA NA NA NA 3947 XR_006391636.1 48 13 21 7 11 NA NA NA NA NA NA 3948 XM_029328627.2 85 62 77 109 123 NA NA NA NA NA NA 3949 XM_044315694.1 24 138 0 402 548 NA NA NA NA NA NA 3950 XM_029338029.2 2406 2352 1447 3338 3564 Q5REU4 0 Staphylococcal nuclease domain-containing protein 1 (EC 3.1.31.1) (100 kDa coactivator) (p100 co-activator) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) RNA-mediated gene silencing [GO:0031047] GO:0003676; GO:0004519; GO:0005634; GO:0016442; GO:0031047; GO:0042470 3951 XM_029344835.2 666 863 585 363 411 NA NA NA NA NA NA 3952 XM_029325016.2 677 500 504 577 687 Q5XGY1 0 Pre-rRNA-processing protein TSR1 homolog Xenopus laevis (African clawed frog) ribosome biogenesis [GO:0042254] GO:0005730; GO:0042254 3953 XM_044307741.1 2 1 17 0 14 Q9U6Y6 3.37e-88 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 3954 XM_044318384.1 8 0 1 1 7 NA NA NA NA NA NA 3955 XM_029345943.2 0 0 6 0 0 O15439 0 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 3956 XR_006394073.1 22 15 28 35 4 NA NA NA NA NA NA 3957 XM_044311145.1 91 0 141 229 68 NA NA NA NA NA NA 3958 XM_044328997.1 1231 1159 685 1358 949 Q5TYW4 0 NBAS subunit of NRZ tethering complex (Neuroblastoma-amplified gene protein homolog) (Neuroblastoma-amplified sequence) Danio rerio (Zebrafish) (Brachydanio rerio) chordate embryonic development [GO:0043009]; embryonic viscerocranium morphogenesis [GO:0048703]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] GO:0000149; GO:0000184; GO:0000956; GO:0005789; GO:0006890; GO:0015031; GO:0043009; GO:0048703; GO:0070939; GO:2000623 3959 XM_029334149.2 303 32 224 101 884 E7EY42 1.01e-172 Phosphatidylserine synthase 2 (PSS-2) (PtdSer synthase 2) (EC 2.7.8.29) (Serine-exchange enzyme II) Danio rerio (Zebrafish) (Brachydanio rerio) phosphatidylserine biosynthetic process [GO:0006659] GO:0005789; GO:0006659; GO:0106245 3960 XM_044307189.1 493 13 237 86 242 NA NA NA NA NA NA 3961 XM_029345923.2 341 148 137 244 315 O62763 1.07e-79 Acetylcholinesterase (AChE) (EC 3.1.1.7) Felis catus (Cat) (Felis silvestris catus) acetylcholine catabolic process [GO:0006581]; choline metabolic process [GO:0019695] GO:0003990; GO:0005615; GO:0005886; GO:0006581; GO:0019695; GO:0045202 3962 XM_029352505.2 6585 8541 3977 5592 4665 Q8AWF2 2.72e-58 Nascent polypeptide-associated complex subunit alpha (NAC-alpha) (Alpha-NAC) Oreochromis niloticus (Nile tilapia) (Tilapia nilotica) protein transport [GO:0015031] GO:0005854; GO:0015031 3963 XM_044313631.1 2001 2182 1576 1571 2686 A3KPW9 1.76e-23 Large proline-rich protein BAG6 (BCL2-associated athanogene 6) (HLA-B-associated transcript 3) Danio rerio (Zebrafish) (Brachydanio rerio) brain development [GO:0007420]; chromatin organization [GO:0006325]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; ER-associated misfolded protein catabolic process [GO:0071712]; internal peptidyl-lysine acetylation [GO:0018393]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; lung development [GO:0030324]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of proteolysis [GO:0045861]; proteasomal protein catabolic process [GO:0010498]; protein stabilization [GO:0050821]; regulation of apoptotic process [GO:0042981]; regulation of embryonic development [GO:0045995]; spermatogenesis [GO:0007283]; synaptonemal complex assembly [GO:0007130]; tail-anchored membrane protein insertion into ER membrane [GO:0071816]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0001822; GO:0005576; GO:0005634; GO:0005829; GO:0006325; GO:0006511; GO:0007130; GO:0007283; GO:0007420; GO:0010498; GO:0018393; GO:0030324; GO:0030433; GO:0031593; GO:0032435; GO:0042771; GO:0042981; GO:0043022; GO:0045861; GO:0045995; GO:0050821; GO:0051787; GO:0061857; GO:0070059; GO:0070628; GO:0071712; GO:0071816; GO:0071818 3964 XM_044315075.1 0 5 2 15 2 NA NA NA NA NA NA 3965 XM_029356832.2 25 4 34 27 65 B1AS29 9.9e-83 Glutamate receptor ionotropic, kainate 3 (GluK3) (Glutamate receptor 7) (GluR-7) (GluR7) Mus musculus (Mouse) G protein-coupled glutamate receptor signaling pathway [GO:0007216]; glutamate receptor signaling pathway [GO:0007215]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; regulation of membrane potential [GO:0042391]; synaptic transmission, glutamatergic [GO:0035249] GO:0001640; GO:0004970; GO:0005886; GO:0007215; GO:0007216; GO:0008066; GO:0015276; GO:0015277; GO:0030424; GO:0030425; GO:0032839; GO:0032983; GO:0035249; GO:0038023; GO:0042391; GO:0042734; GO:0043195; GO:0043204; GO:0045211; GO:0050804; GO:0051967; GO:0098978; GO:0099507; GO:1904315 3966 XM_029331390.2 45 108 84 73 123 P38661 1.2e-48 Probable protein disulfide-isomerase A6 (EC 5.3.4.1) (P5) Medicago sativa (Alfalfa) NA GO:0003756; GO:0005788 3967 XM_029340556.2 325 75 63 150 244 Q59990 1.56e-28 Putative cytochrome P450 120 (EC 1.14.-.-) Synechocystis sp. (strain PCC 6803 / Kazusa) sterol metabolic process [GO:0016125] GO:0004497; GO:0005506; GO:0016125; GO:0016491; GO:0016705; GO:0020037 3968 XM_044318283.1 0 7 0 1 0 NA NA NA NA NA NA 3969 XM_044325413.1 1824 1962 998 2228 1976 Q791B0 2.44e-27 Ubiquitin-like protein 5 (Beacon protein) Psammomys obesus (Fat sand rat) protein modification process [GO:0036211] GO:0005737; GO:0036211 3970 XM_044328296.1 1404 669 870 1582 1035 NA NA NA NA NA NA 3971 XM_029327135.2 110 35 83 185 109 Q9H4G4 5.45e-26 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Homo sapiens (Human) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070062; GO:0070374 3972 XR_006397352.1 182 81 155 117 84 NA NA NA NA NA NA 3973 XM_044321236.1 9 23 5 5 77 NA NA NA NA NA NA 3974 XM_029356368.2 31 114 0 182 81 P55112 4.73e-37 Zinc metalloproteinase nas-4 (EC 3.4.24.-) (Nematode astacin 4) Caenorhabditis elegans proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0006508; GO:0008270 3975 XM_044317760.1 127 79 112 235 159 P23468 5.92e-130 Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48) Homo sapiens (Human) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; neuron differentiation [GO:0030182]; phosphate-containing compound metabolic process [GO:0006796]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse assembly [GO:0051965]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; regulation of immune response [GO:0050776]; regulation of postsynaptic density assembly [GO:0099151]; synaptic membrane adhesion [GO:0099560]; trans-synaptic signaling by trans-synaptic complex [GO:0099545]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185] GO:0004725; GO:0005001; GO:0005102; GO:0005886; GO:0006470; GO:0006796; GO:0007157; GO:0007185; GO:0030182; GO:0042734; GO:0046426; GO:0050775; GO:0050776; GO:0050804; GO:0050839; GO:0051965; GO:0070062; GO:0097105; GO:0098685; GO:0098686; GO:0098978; GO:0099054; GO:0099151; GO:0099545; GO:0099560 3976 XM_044317760.1 127 79 112 235 159 P23468 4.99e-55 Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48) Homo sapiens (Human) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; neuron differentiation [GO:0030182]; phosphate-containing compound metabolic process [GO:0006796]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse assembly [GO:0051965]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; regulation of immune response [GO:0050776]; regulation of postsynaptic density assembly [GO:0099151]; synaptic membrane adhesion [GO:0099560]; trans-synaptic signaling by trans-synaptic complex [GO:0099545]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185] GO:0004725; GO:0005001; GO:0005102; GO:0005886; GO:0006470; GO:0006796; GO:0007157; GO:0007185; GO:0030182; GO:0042734; GO:0046426; GO:0050775; GO:0050776; GO:0050804; GO:0050839; GO:0051965; GO:0070062; GO:0097105; GO:0098685; GO:0098686; GO:0098978; GO:0099054; GO:0099151; GO:0099545; GO:0099560 3977 XM_044328395.1 70 425 38 576 527 Q505B7 6.67e-37 Protein archease (Protein ZBTB8OS) Mus musculus (Mouse) tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388] GO:0006388; GO:0046872; GO:0072669 3978 XR_006391519.1 20 6 8 9 22 NA NA NA NA NA NA 3979 XM_029324720.2 70 0 0 0 11 P48630 2.09e-115 Omega-6 fatty acid desaturase, endoplasmic reticulum isozyme 1 (EC 1.14.19.-) Glycine max (Soybean) (Glycine hispida) unsaturated fatty acid biosynthetic process [GO:0006636] GO:0005789; GO:0006636; GO:0016491 3980 XM_044322035.1 17 1 0 25 0 NA NA NA NA NA NA 3981 XR_006393838.1 24 54 38 80 56 NA NA NA NA NA NA 3982 XM_029342209.2 418 379 231 329 369 Q68EI0 3.03e-92 WD repeat-containing protein 18 Danio rerio (Zebrafish) (Brachydanio rerio) determination of left/right symmetry [GO:0007368]; DNA-templated DNA replication [GO:0006261]; Kupffer's vesicle development [GO:0070121]; rRNA processing [GO:0006364] GO:0005656; GO:0005730; GO:0006261; GO:0006364; GO:0007368; GO:0070121; GO:0097344; GO:0120293 3983 XM_044328224.1 43 281 103 1093 1178 P05772 0 Protein kinase C beta type (PKC-B) (PKC-beta) (EC 2.7.11.13) Oryctolagus cuniculus (Rabbit) adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; B cell activation [GO:0042113]; B cell receptor signaling pathway [GO:0050853]; chromatin organization [GO:0006325]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; positive regulation of angiogenesis [GO:0045766]; positive regulation of B cell receptor signaling pathway [GO:0050861]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; post-translational protein modification [GO:0043687]; protein phosphorylation [GO:0006468]; regulation of glucose transmembrane transport [GO:0010827]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0002250; GO:0003682; GO:0004697; GO:0004698; GO:0005524; GO:0005634; GO:0005829; GO:0006325; GO:0006357; GO:0006468; GO:0006915; GO:0008270; GO:0010827; GO:0010829; GO:0016020; GO:0030374; GO:0030949; GO:0035403; GO:0042113; GO:0042393; GO:0043123; GO:0043687; GO:0045766; GO:0046627; GO:0050681; GO:0050853; GO:0050861; GO:0051092; GO:0106310 3984 XM_029348131.2 0 0 0 0 103 P58058 2.99e-122 NAD kinase (EC 2.7.1.23) (Poly(P)/ATP NAD kinase) Mus musculus (Mouse) NAD metabolic process [GO:0019674]; NADP biosynthetic process [GO:0006741]; phosphorylation [GO:0016310]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774] GO:0003951; GO:0005524; GO:0005829; GO:0006741; GO:0016310; GO:0019674; GO:0035774; GO:0046872 3985 XM_044309358.1 52 61 41 42 13 NA NA NA NA NA NA 3986 XM_029347044.2 13 18 4 17 16 NA NA NA NA NA NA 3987 XM_044314502.1 0 8 0 0 12 Q810D6 9.81e-33 Glutamate-rich WD repeat-containing protein 1 (Protein A301) Mus musculus (Mouse) DNA replication [GO:0006260]; nucleosome assembly [GO:0006334]; nucleosome disassembly [GO:0006337]; ribosome biogenesis [GO:0042254] GO:0003682; GO:0003688; GO:0005634; GO:0005654; GO:0005694; GO:0005730; GO:0005829; GO:0006260; GO:0006334; GO:0006337; GO:0032991; GO:0042254; GO:0042393 3988 XM_044314502.1 0 8 0 0 12 Q810D6 9.81e-33 Glutamate-rich WD repeat-containing protein 1 (Protein A301) Mus musculus (Mouse) DNA replication [GO:0006260]; nucleosome assembly [GO:0006334]; nucleosome disassembly [GO:0006337]; ribosome biogenesis [GO:0042254] GO:0003682; GO:0003688; GO:0005634; GO:0005654; GO:0005694; GO:0005730; GO:0005829; GO:0006260; GO:0006334; GO:0006337; GO:0032991; GO:0042254; GO:0042393 3989 XM_044326351.1 25 4 20 96 125 Q9NU19 2.55e-163 TBC1 domain family member 22B Homo sapiens (Human) activation of GTPase activity [GO:0090630] GO:0005096; GO:0071889; GO:0090630 3990 XM_044309022.1 0 0 0 0 19 P20664 5.64e-159 DNA primase small subunit (EC 2.7.7.102) (DNA primase 49 kDa subunit) (p49) Mus musculus (Mouse) DNA replication initiation [GO:0006270]; DNA replication, synthesis of RNA primer [GO:0006269] GO:0000287; GO:0003896; GO:0005658; GO:0006269; GO:0006270; GO:0008270; GO:0032553 3991 XM_029337742.2 4072 9061 2935 4181 2482 NA NA NA NA NA NA 3992 XM_029332825.2 0 0 0 0 38 O42611 0 Protein HIRA (TUP1-like enhancer of split protein 1) Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) chromatin organization [GO:0006325]; DNA-templated transcription [GO:0006351]; regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006325; GO:0006351; GO:0006355 3993 XM_029332825.2 0 0 0 0 38 O42611 6.56e-66 Protein HIRA (TUP1-like enhancer of split protein 1) Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) chromatin organization [GO:0006325]; DNA-templated transcription [GO:0006351]; regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006325; GO:0006351; GO:0006355 3994 XM_029342855.2 636 185 244 452 278 O88351 1.42e-152 Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) (IKK-B) (IKK-beta) (IkBKB) (EC 2.7.11.10) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB) (Serine/threonine protein kinase IKBKB) (EC 2.7.11.1) Mus musculus (Mouse) B cell homeostasis [GO:0001782]; cellular response to tumor necrosis factor [GO:0071356]; cortical actin cytoskeleton organization [GO:0030866]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; I-kappaB phosphorylation [GO:0007252]; interleukin-1-mediated signaling pathway [GO:0070498]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; neuron projection development [GO:0031175]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of sodium ion transport [GO:0010765]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; protein phosphorylation [GO:0006468]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of phosphorylation [GO:0042325]; response to cholecystokinin [GO:0061847]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0001782; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006468; GO:0007249; GO:0007252; GO:0008284; GO:0008384; GO:0008385; GO:0009898; GO:0010765; GO:0010976; GO:0018105; GO:0019901; GO:0019903; GO:0030866; GO:0031175; GO:0033209; GO:0035509; GO:0035631; GO:0042325; GO:0042802; GO:0042803; GO:0043123; GO:0043231; GO:0044877; GO:0045121; GO:0045944; GO:0046982; GO:0051092; GO:0061847; GO:0070498; GO:0071356; GO:0072659; GO:0097110; GO:0106310; GO:1901216; GO:1903140; GO:1903347; GO:1990459; GO:2001259 3995 XR_006391824.1 227 37 6 68 79 NA NA NA NA NA NA 3996 XM_044311276.1 508 35 222 332 159 F1R4Y7 7.47e-60 Centrosomal protein of 83 kDa (Cep83) (Coiled-coil domain-containing protein 41) Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; establishment of centrosome localization [GO:0051660] GO:0005737; GO:0005814; GO:0051660; GO:0060271; GO:0097539 3997 XM_029331338.2 1907 1012 1278 2190 2053 Q5THJ4 0 Intermembrane lipid transfer protein VPS13D (Vacuolar protein sorting-associated protein 13D) Homo sapiens (Human) lipid transport [GO:0006869]; mitochondrion organization [GO:0007005]; positive regulation of mitophagy [GO:1901526]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623] GO:0006623; GO:0006869; GO:0007005; GO:0019898; GO:0045053; GO:0070062; GO:1901526 3998 XM_044325114.1 4 48 6 15 0 NA NA NA NA NA NA 3999 XR_006392452.1 0 0 0 0 19 NA NA NA NA NA NA 4000 XM_029327733.2 218 249 169 185 104 NA NA NA NA NA NA 4001 XM_044328757.1 162 175 214 296 293 NA NA NA NA NA NA 4002 XM_029328652.2 0 0 13 0 0 Q5R6J1 6.99e-88 Sodium-dependent neutral amino acid transporter B(0)AT1 (Solute carrier family 6 member 19) (System B(0) neutral amino acid transporter AT1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0015175; GO:0015293; GO:0016324 4003 XM_044324016.1 0 0 0 0 50 NA NA NA NA NA NA 4004 XM_044324892.1 1185 860 508 1095 778 Q6UKI2 9.97e-42 Protein amnionless [Cleaved into: Soluble protein amnionless] Canis lupus familiaris (Dog) (Canis familiaris) protein localization [GO:0008104]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0005576; GO:0005905; GO:0006898; GO:0008104; GO:0010008; GO:0015031; GO:0016324; GO:0030139 4005 XM_029336497.2 950 217 232 468 435 Q8JG54 1.91e-57 Repulsive guidance molecule A Gallus gallus (Chicken) BMP signaling pathway [GO:0030509] GO:0005886; GO:0015026; GO:0030509 4006 XM_029330086.2 2323 1917 607 1432 1626 Q0MQ86 1.22e-29 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (Complex I-B17.2) (CI-B17.2) (CIB17.2) (NADH-ubiquinone oxidoreductase subunit B17.2) Gorilla gorilla gorilla (Western lowland gorilla) mitochondrial ATP synthesis coupled electron transport [GO:0042775]; mitochondrial respiratory chain complex I assembly [GO:0032981]; response to oxidative stress [GO:0006979] GO:0005747; GO:0005829; GO:0006979; GO:0032981; GO:0042775 4007 XM_044326039.1 4010 3328 2290 4319 2987 Q9EQW7 0 Kinesin-like protein KIF13A Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; endosome to lysosome transport [GO:0008333]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; melanosome organization [GO:0032438]; microtubule-based movement [GO:0007018]; plus-end-directed vesicle transport along microtubule [GO:0072383]; regulation of cytokinesis [GO:0032465]; vesicle cargo loading [GO:0035459] GO:0000139; GO:0003777; GO:0005524; GO:0005813; GO:0005871; GO:0005874; GO:0006886; GO:0007018; GO:0007049; GO:0008017; GO:0008333; GO:0010008; GO:0016887; GO:0030496; GO:0032438; GO:0032465; GO:0032588; GO:0035459; GO:0043001; GO:0051301; GO:0072383 4008 XR_006392191.1 4 0 0 0 6 NA NA NA NA NA NA 4009 XM_044321247.1 0 3 0 9 1 NA NA NA NA NA NA 4010 XM_044324267.1 320 196 301 422 314 Q9VBW3 2.81e-82 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 4011 XM_029329468.2 16068 14665 11512 11793 9445 Q13118 4.11e-59 Krueppel-like factor 10 (EGR-alpha) (Transforming growth factor-beta-inducible early growth response protein 1) (TGFB-inducible early growth response protein 1) (TIEG-1) Homo sapiens (Human) bone mineralization [GO:0030282]; cell-cell signaling [GO:0007267]; cellular response to starvation [GO:0009267]; circadian rhythm [GO:0007623]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of circadian rhythm [GO:0042752]; regulation of transcription by RNA polymerase II [GO:0006357]; somatic stem cell population maintenance [GO:0035019] GO:0000122; GO:0000785; GO:0000978; GO:0000981; GO:0001046; GO:0001228; GO:0003700; GO:0005634; GO:0006357; GO:0007267; GO:0007623; GO:0008285; GO:0009267; GO:0030282; GO:0035019; GO:0042752; GO:0045672; GO:0045892; GO:0045944; GO:0046872; GO:1990837 4012 XM_029332424.2 3 4 314 0 9 P84239 3.07e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 4013 XM_029342370.2 0 29 17 0 0 Q8N3J2 2.22e-50 N(6)-adenine-specific methyltransferase METTL4 (Methyltransferase-like protein 4) (N(6)-adenine-specific DNA methyltransferase METTL4) (EC 2.1.1.72) (snRNA (2'-O-methyladenosine-N(6)-)-methyltransferase METTL4) (EC 2.1.1.-) Homo sapiens (Human) chromatin organization [GO:0006325]; DNA methylation on adenine [GO:0032775]; regulation of chromatin organization [GO:1902275]; regulation of mitochondrial DNA replication [GO:0090296]; regulation of mitochondrial transcription [GO:1903108]; regulation of RNA splicing [GO:0043484]; snRNA (adenine-N6)-methylation [GO:0120049] GO:0003676; GO:0005634; GO:0005759; GO:0005829; GO:0006325; GO:0008168; GO:0008173; GO:0009007; GO:0032775; GO:0043484; GO:0090296; GO:0106347; GO:0120049; GO:1902275; GO:1903108 4014 XM_029331886.2 1426 958 1164 2654 2281 O57460 1.5e-35 Dorsal-ventral patterning tolloid-like protein 1 (EC 3.4.24.-) (Mini fin protein) Danio rerio (Zebrafish) (Brachydanio rerio) blood vessel development [GO:0001568]; determination of ventral identity [GO:0048264]; dorsal/ventral pattern formation [GO:0009953]; embryonic caudal fin morphogenesis [GO:0035124]; embryonic hemopoiesis [GO:0035162]; endothelial cell development [GO:0001885]; mesoderm formation [GO:0001707]; positive regulation of BMP signaling pathway [GO:0030513]; post-anal tail morphogenesis [GO:0036342]; protein processing [GO:0016485]; proteolysis [GO:0006508] GO:0001568; GO:0001707; GO:0001885; GO:0004222; GO:0005509; GO:0005576; GO:0005615; GO:0006508; GO:0008233; GO:0008237; GO:0008270; GO:0009953; GO:0016485; GO:0030513; GO:0035124; GO:0035162; GO:0036342; GO:0048264 4015 XM_044317916.1 219 180 133 268 408 O15439 0 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 4016 XM_044328755.1 0 0 26 0 0 C3YWU0 1.06e-169 Alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucoside fucohydrolase) Branchiostoma floridae (Florida lancelet) (Amphioxus) fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139] GO:0004560; GO:0005576; GO:0005764; GO:0006004; GO:0016139 4017 XM_044311680.1 25 15 71 23 172 B8VIU6 7.87e-58 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 4018 XM_044320389.1 298 220 250 137 246 Q3UTQ8 1.93e-154 Cyclin-dependent kinase-like 5 (EC 2.7.11.22) Mus musculus (Mouse) modulation of chemical synaptic transmission [GO:0050804]; neuron migration [GO:0001764]; positive regulation of axon extension [GO:0045773]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of GTPase activity [GO:0043547]; protein autophosphorylation [GO:0046777]; protein localization to nucleus [GO:0034504]; protein phosphorylation [GO:0006468]; regulation of cilium assembly [GO:1902017]; regulation of dendrite development [GO:0050773]; regulation of postsynapse organization [GO:0099175] GO:0001764; GO:0004672; GO:0004693; GO:0005524; GO:0005634; GO:0005654; GO:0005813; GO:0006468; GO:0016301; GO:0031267; GO:0032587; GO:0032839; GO:0034504; GO:0036064; GO:0043547; GO:0044294; GO:0045202; GO:0045773; GO:0046777; GO:0048471; GO:0050773; GO:0050775; GO:0050804; GO:0060999; GO:0097542; GO:0098978; GO:0099092; GO:0099175; GO:0106310; GO:1902017 4019 XM_044312642.1 85 48 72 35 143 P61752 9.28e-30 Histamine H2 receptor (H2R) (HH2R) (Gastric receptor I) Pongo pygmaeus (Bornean orangutan) gastric acid secretion [GO:0001696]; positive regulation of vasoconstriction [GO:0045907] GO:0001696; GO:0004969; GO:0005886; GO:0045907 4020 XM_044323849.1 732 789 494 536 447 G8HTB6 2.33e-34 ZP domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 4021 XM_044307582.1 1589 896 962 1533 1827 Q13435 0 Splicing factor 3B subunit 2 (Pre-mRNA-splicing factor SF3b 145 kDa subunit) (SF3b145) (Spliceosome-associated protein 145) (SAP 145) Homo sapiens (Human) mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]; U2-type prespliceosome assembly [GO:1903241] GO:0000398; GO:0003723; GO:0005634; GO:0005654; GO:0005681; GO:0005684; GO:0005686; GO:0005689; GO:0006397; GO:0008380; GO:0016607; GO:0071005; GO:0071011; GO:0071013; GO:1903241 4022 XM_044326718.1 0 0 0 0 11 NA NA NA NA NA NA 4023 XM_044328267.1 3636 2464 2503 3390 3926 O75334 1.28e-124 Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2) Homo sapiens (Human) cell-matrix adhesion [GO:0007160]; dense core granule cytoskeletal transport [GO:0099519]; regulation of dendritic spine development [GO:0060998]; regulation of dendritic spine morphogenesis [GO:0061001]; synapse organization [GO:0050808] GO:0005737; GO:0005829; GO:0007160; GO:0009986; GO:0030424; GO:0043197; GO:0048786; GO:0050808; GO:0060998; GO:0061001; GO:0070062; GO:0099519 4024 XM_044328267.1 3636 2464 2503 3390 3926 O75334 2.28e-114 Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2) Homo sapiens (Human) cell-matrix adhesion [GO:0007160]; dense core granule cytoskeletal transport [GO:0099519]; regulation of dendritic spine development [GO:0060998]; regulation of dendritic spine morphogenesis [GO:0061001]; synapse organization [GO:0050808] GO:0005737; GO:0005829; GO:0007160; GO:0009986; GO:0030424; GO:0043197; GO:0048786; GO:0050808; GO:0060998; GO:0061001; GO:0070062; GO:0099519 4025 XM_029353810.2 1958 1444 991 1753 1710 Q6DEU9 0 RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) endodermal cell fate commitment [GO:0001711]; histone H3-K4 trimethylation [GO:0080182]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of histone H3-K79 methylation [GO:2001162]; stem cell population maintenance [GO:0019827]; transcription elongation by RNA polymerase II promoter [GO:0006368] GO:0000122; GO:0000791; GO:0001711; GO:0006368; GO:0016593; GO:0016607; GO:0019827; GO:0045638; GO:0051571; GO:0080182; GO:2001162 4026 XM_029350489.2 1076 758 565 1131 619 P34275 8.04e-141 Probable acyl-CoA dehydrogenase 6 (Probable isovaleryl-CoA dehydrogenase) (IVD) (EC 1.3.8.4) Caenorhabditis elegans fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; leucine catabolic process [GO:0006552] GO:0003995; GO:0005737; GO:0006552; GO:0008470; GO:0033539; GO:0050660 4027 XM_044313616.1 85 67 51 35 79 Q6DG03 2.51e-45 Cyclin-D-binding Myb-like transcription factor 1 Danio rerio (Zebrafish) (Brachydanio rerio) cell cycle [GO:0007049]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000976; GO:0000978; GO:0000981; GO:0003700; GO:0005634; GO:0006355; GO:0006357; GO:0007049 4028 XM_029348305.2 78 87 96 178 221 NA NA NA NA NA NA 4029 XM_044310490.1 831 347 386 863 132 NA NA NA NA NA NA 4030 XM_029342374.2 237 140 96 233 358 Q90X38 6.41e-67 G-patch domain and KOW motifs-containing protein (Protein T54-like) Danio rerio (Zebrafish) (Brachydanio rerio) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0003723; GO:0005634; GO:0005681 4031 XM_044327596.1 92 258 48 151 159 Q7RTR2 3.99e-38 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4032 XM_044327596.1 92 258 48 151 159 Q7RTR2 7.22e-33 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4033 XM_044327596.1 92 258 48 151 159 Q7RTR2 5.48e-30 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4034 XM_044327596.1 92 258 48 151 159 Q7RTR2 1.44e-25 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4035 XR_006391429.1 21 11 27 1 31 NA NA NA NA NA NA 4036 XM_044319030.1 5 0 0 18 22 Q76KP1 5.84e-56 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Homo sapiens (Human) NA GO:0008376; GO:0032580; GO:0033842 4037 XM_044319030.1 5 0 0 18 22 Q76KP1 9.18e-23 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Homo sapiens (Human) NA GO:0008376; GO:0032580; GO:0033842 4038 XM_044323620.1 17 3 0 0 0 Q96MB7 7.63e-35 Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease) Homo sapiens (Human) NA GO:0004518; GO:0005634; GO:0005829; GO:0005886; GO:0034451; GO:0046872 4039 XM_044325500.1 89 62 30 84 147 NA NA NA NA NA NA 4040 XM_029326980.2 127 283 5 69 7 Q9UJX0 2.09e-122 Oxidative stress-induced growth inhibitor 1 (Bone marrow stromal cell-derived growth inhibitor) (BMSC-derived growth inhibitor) (Ovary, kidney and liver protein 38) (huOKL38) (Pregnancy-induced growth inhibitor OKL38) Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of cell growth [GO:0030308]; regulation of apoptotic process [GO:0042981]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127] GO:0008083; GO:0030154; GO:0030308; GO:0030334; GO:0042127; GO:0042981 4041 XM_044307246.1 872 1572 374 586 604 Q5XI69 0 Probable ATP-dependent RNA helicase DHX40 (EC 3.6.4.13) (DEAH box protein 40) Rattus norvegicus (Rat) NA GO:0003723; GO:0003724; GO:0005524; GO:0016887 4042 XM_044307832.1 286 348 0 25 290 NA NA NA NA NA NA 4043 XM_029348929.2 68 0 64 164 1 Q4R6I5 4.5e-27 Clathrin heavy chain linker domain-containing protein 1 Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA NA 4044 XM_044326106.1 0 6 0 5 5 NA NA NA NA NA NA 4045 XM_029351238.2 0 0 259 363 0 Q66H20 2.63e-142 Polypyrimidine tract-binding protein 2 (Neural polypyrimidine tract-binding protein) (PTB-like protein) Rattus norvegicus (Rat) cerebellum development [GO:0021549]; mRNA splice site selection [GO:0006376]; negative regulation of RNA splicing [GO:0033119]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of RNA splicing [GO:0043484]; spinal cord development [GO:0021510] GO:0003729; GO:0005634; GO:0005681; GO:0006376; GO:0021510; GO:0021549; GO:0030426; GO:0033119; GO:0043025; GO:0043484; GO:2000177 4046 XR_006395300.1 0 12 6 2 2 NA NA NA NA NA NA 4047 XM_044319198.1 34 19 36 219 263 NA NA NA NA NA NA 4048 XM_044326764.1 30 0 0 0 13 NA NA NA NA NA NA 4049 XM_044320090.1 445 203 155 376 285 Q9TU53 8.39e-27 Cubilin Canis lupus familiaris (Dog) (Canis familiaris) cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031] GO:0005509; GO:0005765; GO:0005768; GO:0005905; GO:0008203; GO:0015031; GO:0016324; GO:0031419; GO:0031526; GO:0043235 4050 XM_029332774.2 20568 15997 10383 13570 16501 P62494 8.73e-126 Ras-related protein Rab-11A (Rab-11) (EC 3.6.5.2) (24KG) Rattus norvegicus (Rat) amyloid-beta clearance by transcytosis [GO:0150093]; astral microtubule organization [GO:0030953]; establishment of protein localization to membrane [GO:0090150]; establishment of protein localization to organelle [GO:0072594]; establishment of vesicle localization [GO:0051650]; exocytosis [GO:0006887]; exosomal secretion [GO:1990182]; intracellular cholesterol transport [GO:0032367]; melanosome transport [GO:0032402]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly [GO:0090307]; multivesicular body assembly [GO:0036258]; neuron projection development [GO:0031175]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; positive regulation of axon extension [GO:0045773]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; regulation of cytokinesis [GO:0032465]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multivesicular body size [GO:0010796]; regulation of protein transport [GO:0051223]; regulation of vesicle-mediated transport [GO:0060627]; vesicle-mediated transport [GO:0016192]; vesicle-mediated transport in synapse [GO:0099003] GO:0000922; GO:0003924; GO:0003925; GO:0005525; GO:0005737; GO:0005768; GO:0005771; GO:0005794; GO:0005802; GO:0005813; GO:0005814; GO:0005829; GO:0006887; GO:0007080; GO:0008017; GO:0010634; GO:0010796; GO:0010971; GO:0016020; GO:0016192; GO:0030133; GO:0030424; GO:0030953; GO:0031175; GO:0031410; GO:0031489; GO:0031982; GO:0032154; GO:0032367; GO:0032402; GO:0032465; GO:0032991; GO:0034394; GO:0036258; GO:0045335; GO:0045773; GO:0048169; GO:0048471; GO:0051223; GO:0051650; GO:0055037; GO:0055038; GO:0060627; GO:0070062; GO:0072594; GO:0072659; GO:0090150; GO:0090307; GO:0098685; GO:0098837; GO:0098887; GO:0098978; GO:0099003; GO:0150093; GO:1903078; GO:1990182 4051 XM_029346438.2 85 164 52 79 112 D3Z8N4 2e-85 Kelch-like protein 20 Rattus norvegicus (Rat) Golgi to endosome transport [GO:0006895]; negative regulation of apoptotic process [GO:0043066]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K33-linked ubiquitination [GO:1990390]; protein transport [GO:0015031]; protein ubiquitination [GO:0016567] GO:0003779; GO:0004842; GO:0005737; GO:0005802; GO:0005829; GO:0006895; GO:0015031; GO:0016567; GO:0016605; GO:0019964; GO:0030424; GO:0030425; GO:0031463; GO:0043066; GO:0043161; GO:0048471; GO:1990390 4052 XR_006396458.1 157 39 44 46 67 NA NA NA NA NA NA 4053 XM_044322493.1 297 166 105 279 216 Q8BUB6 6.65e-43 Uronyl 2-sulfotransferase (EC 2.8.2.-) Mus musculus (Mouse) establishment of cell polarity [GO:0030010]; regulation of axonogenesis [GO:0050770] GO:0000139; GO:0008146; GO:0030010; GO:0050770 4054 XM_029331068.2 852 761 664 1004 662 Q32LL5 3.34e-29 Integrator complex subunit 12 (Int12) (PHD finger protein 22) Bos taurus (Bovine) snRNA 3'-end processing [GO:0034472] GO:0005634; GO:0032039; GO:0034472; GO:0046872 4055 XM_044315131.1 65 1032 188 88 218 NA NA NA NA NA NA 4056 XM_044323388.1 0 0 0 511 430 A4D1E9 2.12e-63 GTP-binding protein 10 (Protein obg homolog 2) (ObgH2) Homo sapiens (Human) ribosome biogenesis [GO:0042254] GO:0000287; GO:0003723; GO:0003924; GO:0005525; GO:0005694; GO:0005730; GO:0005739; GO:0042254 4057 XM_044321460.1 536 758 577 609 352 Q0P4F7 0 Medium-chain acyl-CoA ligase ACSF2, mitochondrial (EC 6.2.1.2) Danio rerio (Zebrafish) (Brachydanio rerio) fatty acid metabolic process [GO:0006631] GO:0005524; GO:0005739; GO:0006631; GO:0031956; GO:0047760 4058 XM_044320518.1 0 0 0 0 23 NA NA NA NA NA NA 4059 XM_044317099.1 2390 2085 977 1108 575 NA NA NA NA NA NA 4060 XM_044329320.1 0 0 0 63 62 NA NA NA NA NA NA 4061 XR_006395488.1 2 6 0 0 2 NA NA NA NA NA NA 4062 XM_029357252.2 802 599 358 695 430 P15535 3e-83 Beta-1,4-galactosyltransferase 1 (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (EC 2.4.1.-) (Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase) (Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase) (EC 2.4.1.38) (Lactose synthase A protein) (EC 2.4.1.22) (N-acetyllactosamine synthase) (EC 2.4.1.90) (Nal synthase) (Neolactotriaosylceramide beta-1,4-galactosyltransferase) (EC 2.4.1.275) (UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 1) (UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 1) [Cleaved into: Processed beta-1,4-galactosyltransferase 1] Mus musculus (Mouse) acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; cell population proliferation [GO:0008283]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; epithelial cell proliferation [GO:0050673]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; glycoprotein biosynthetic process [GO:0009101]; glycosylation [GO:0070085]; lactose biosynthetic process [GO:0005989]; lipid metabolic process [GO:0006629]; macrophage migration [GO:1905517]; negative regulation of epithelial cell proliferation [GO:0050680]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein glycosylation [GO:0006486]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]; wound healing [GO:0042060] GO:0000138; GO:0002064; GO:0002526; GO:0003831; GO:0003945; GO:0004461; GO:0005576; GO:0005794; GO:0005886; GO:0005989; GO:0006012; GO:0006486; GO:0006487; GO:0006629; GO:0007155; GO:0007339; GO:0007341; GO:0008092; GO:0008283; GO:0008378; GO:0009101; GO:0009312; GO:0009897; GO:0009986; GO:0016323; GO:0030057; GO:0030145; GO:0030175; GO:0030198; GO:0031526; GO:0032580; GO:0032991; GO:0035250; GO:0042060; GO:0042802; GO:0043014; GO:0043065; GO:0045136; GO:0048487; GO:0050673; GO:0050680; GO:0060046; GO:0060054; GO:0060055; GO:0070085; GO:1905517 4063 XR_006393055.1 0 32 45 3 45 NA NA NA NA NA NA 4064 XM_044318301.1 21 43 26 0 76 NA NA NA NA NA NA 4065 XM_029356957.2 372 257 182 264 242 Q8N8Q1 1.63e-34 Probable transmembrane reductase CYB561D1 (EC 7.2.1.3) (Cytochrome b561 domain-containing protein 1) Homo sapiens (Human) NA GO:0016020; GO:0016491; GO:0020037; GO:0046872; GO:0140571; GO:0140575 4066 XM_029339728.2 15118 12784 8688 12503 7941 O61491 0 Flotillin-1 Drosophila melanogaster (Fruit fly) positive regulation of cell junction assembly [GO:1901890]; positive regulation of cell-cell adhesion mediated by cadherin [GO:2000049]; positive regulation of endocytosis [GO:0045807]; protein kinase C signaling [GO:0070528]; protein localization to plasma membrane [GO:0072659]; regulation of receptor internalization [GO:0002090] GO:0002090; GO:0005198; GO:0005737; GO:0005886; GO:0016600; GO:0031410; GO:0045807; GO:0070528; GO:0072659; GO:1901890; GO:2000049 4067 XM_044313678.1 0 10 1 577 54 NA NA NA NA NA NA 4068 XM_029326923.2 52 6 39 27 75 NA NA NA NA NA NA 4069 XM_029339544.2 623 382 265 397 249 Q922Q5 1.93e-138 Adenosine 3'-phospho 5'-phosphosulfate transporter 2 (PAPS transporter 2) (Solute carrier family 35 member B3) Mus musculus (Mouse) NA GO:0000139; GO:0005739; GO:0005789; GO:0022857; GO:0046964 4070 XM_029327611.2 337 144 456 361 220 A4IGL7 2.34e-21 Peroxidasin (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0005576; GO:0005604; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0031012; GO:0042744; GO:0046872; GO:0051260; GO:0070207; GO:0070831; GO:0071711; GO:0140825 4071 XM_029327611.2 337 144 456 361 220 A4IGL7 2.34e-21 Peroxidasin (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0005576; GO:0005604; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0031012; GO:0042744; GO:0046872; GO:0051260; GO:0070207; GO:0070831; GO:0071711; GO:0140825 4072 XM_044325731.1 0 2 2 0 7 NA NA NA NA NA NA 4073 XM_044312820.1 184 182 180 145 176 NA NA NA NA NA NA 4074 XR_006394077.1 0 0 6 2 5 NA NA NA NA NA NA 4075 XM_044316036.1 8 15 14 9 2 NA NA NA NA NA NA 4076 XM_029338872.2 29 18 16 39 23 NA NA NA NA NA NA 4077 XM_044317085.1 21 0 0 0 0 P36544 4.86e-85 Neuronal acetylcholine receptor subunit alpha-7 Homo sapiens (Human) acetylcholine receptor signaling pathway [GO:0095500]; calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; cognition [GO:0050890]; dendrite arborization [GO:0140059]; dendritic spine organization [GO:0097061]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; learning or memory [GO:0007611]; membrane depolarization [GO:0051899]; memory [GO:0007613]; modulation of excitatory postsynaptic potential [GO:0098815]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of tumor necrosis factor production [GO:0032720]; nervous system process [GO:0050877]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of CoA-transferase activity [GO:1905920]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; regulation of amyloid fibril formation [GO:1905906]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of membrane potential [GO:0042391]; regulation of neuron death [GO:1901214]; regulation of nitric oxide metabolic process [GO:0080164]; response to acetylcholine [GO:1905144]; response to amyloid-beta [GO:1904645]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; sensory processing [GO:0050893]; short-term memory [GO:0007614]; signal transduction [GO:0007165]; synapse organization [GO:0050808]; synaptic transmission, cholinergic [GO:0007271] GO:0001540; GO:0001666; GO:0001934; GO:0005216; GO:0005231; GO:0005262; GO:0005886; GO:0005892; GO:0006811; GO:0006816; GO:0006874; GO:0007165; GO:0007268; GO:0007271; GO:0007611; GO:0007613; GO:0007614; GO:0008284; GO:0015464; GO:0015643; GO:0016020; GO:0017081; GO:0022848; GO:0030594; GO:0032720; GO:0034220; GO:0035094; GO:0042166; GO:0042391; GO:0042803; GO:0043005; GO:0043410; GO:0044853; GO:0045202; GO:0045211; GO:0045766; GO:0050808; GO:0050877; GO:0050890; GO:0050893; GO:0051247; GO:0051899; GO:0070374; GO:0080164; GO:0095500; GO:0097061; GO:0098794; GO:0098815; GO:0140059; GO:1900273; GO:1901214; GO:1902004; GO:1902430; GO:1902991; GO:1904315; GO:1904645; GO:1905144; GO:1905906; GO:1905920; GO:2000463 4078 XM_044308089.1 51 0 0 0 0 Q92113 5.84e-137 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Squalus acanthias (Spiny dogfish) steroid biosynthetic process [GO:0006694] GO:0004508; GO:0005506; GO:0006694; GO:0016020; GO:0020037; GO:0047442 4079 XR_006393978.1 7 0 186 3 61 NA NA NA NA NA NA 4080 XM_029330413.2 0 0 0 0 15 Q9EQD2 1.54e-37 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 4081 XM_029335860.2 119 70 80 85 154 Q8C2E4 3.31e-52 Pentatricopeptide repeat-containing protein 1, mitochondrial Mus musculus (Mouse) mitochondrial translation [GO:0032543]; tRNA 3'-end processing [GO:0042780] GO:0000049; GO:0005739; GO:0005759; GO:0032543; GO:0042780 4082 XM_044327286.1 3 7 14 13 4 NA NA NA NA NA NA 4083 XM_044322327.1 1 1 2 0 95 NA NA NA NA NA NA 4084 XM_044325746.1 0 0 7 0 1 NA NA NA NA NA NA 4085 XM_044328184.1 0 0 0 0 6 NA NA NA NA NA NA 4086 XM_029347275.2 260 244 114 282 259 A7SL20 1.91e-49 Ribosomal RNA processing protein 36 homolog Nematostella vectensis (Starlet sea anemone) cleavage involved in rRNA processing [GO:0000469]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462] GO:0000462; GO:0000469; GO:0005730; GO:0030686 4087 XM_029327371.2 675 463 307 840 859 Q552M5 2.25e-27 Ras guanine nucleotide exchange factor Y (RasGEF domain-containing protein Y) Dictyostelium discoideum (Social amoeba) positive regulation of GTPase activity [GO:0043547]; Ras protein signal transduction [GO:0007265] GO:0005085; GO:0005886; GO:0007265; GO:0043547 4088 XM_029350446.2 116 0 0 72 33 Q86YA3 0 Protein ZGRF1 (GRF-type zinc finger domain-containing protein 1) Homo sapiens (Human) replication fork reversal [GO:0071932] GO:0003723; GO:0004386; GO:0005737; GO:0008270; GO:0016020; GO:0017108; GO:0071932 4089 XM_044322413.1 65 0 0 8 140 A7S2N8 0 E3 UFM1-protein ligase 1 homolog (EC 2.3.2.-) (E3 UFM1-protein transferase 1 homolog) Nematostella vectensis (Starlet sea anemone) protein K69-linked ufmylation [GO:1990592]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]; response to endoplasmic reticulum stress [GO:0034976] GO:0005789; GO:0032434; GO:0034976; GO:0061666; GO:0071568; GO:1990592 4090 XM_044316069.1 0 2 0 0 6 NA NA NA NA NA NA 4091 XM_029340072.2 19 38 42 54 75 P0CT39 2.62e-63 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 4092 XM_044327448.1 15 0 15 2 25 Q91ZV2 7.88e-31 Discoidin, CUB and LCCL domain-containing protein 2 (Endothelial and smooth muscle cell-derived neuropilin-like protein) Rattus norvegicus (Rat) negative regulation of cell growth [GO:0030308]; wound healing [GO:0042060] GO:0005886; GO:0009986; GO:0030308; GO:0038023; GO:0042060 4093 XM_029327852.2 419 0 0 0 0 Q5ZL23 2.25e-66 Amyloid beta A4 precursor protein-binding family B member 1-interacting protein (APBB1-interacting protein 1) Gallus gallus (Chicken) signal transduction [GO:0007165] GO:0005829; GO:0005856; GO:0005886; GO:0007165 4094 XM_044322184.1 1153 636 866 1339 1269 Q8VHE0 2.1e-156 Translocation protein SEC63 homolog Mus musculus (Mouse) liver development [GO:0001889]; multicellular organism aging [GO:0010259]; nitrogen compound metabolic process [GO:0006807]; post-translational protein targeting to endoplasmic reticulum membrane [GO:0006620]; post-translational protein targeting to membrane, translocation [GO:0031204]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614] GO:0001889; GO:0005783; GO:0006614; GO:0006620; GO:0006807; GO:0008320; GO:0010259; GO:0016020; GO:0031204; GO:0031207 4095 XM_044322184.1 1153 636 866 1339 1269 Q8VHE0 3.56e-29 Translocation protein SEC63 homolog Mus musculus (Mouse) liver development [GO:0001889]; multicellular organism aging [GO:0010259]; nitrogen compound metabolic process [GO:0006807]; post-translational protein targeting to endoplasmic reticulum membrane [GO:0006620]; post-translational protein targeting to membrane, translocation [GO:0031204]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614] GO:0001889; GO:0005783; GO:0006614; GO:0006620; GO:0006807; GO:0008320; GO:0010259; GO:0016020; GO:0031204; GO:0031207 4096 XM_029333118.2 681 736 401 472 871 Q32KV4 9.8e-107 Cytoplasmic dynein 2 light intermediate chain 1 Bos taurus (Bovine) intraciliary retrograde transport [GO:0035721]; intraciliary transport involved in cilium assembly [GO:0035735]; regulation of cilium assembly [GO:1902017] GO:0005737; GO:0005813; GO:0005868; GO:0005874; GO:0005930; GO:0035721; GO:0035735; GO:0035869; GO:0036064; GO:0045504; GO:1902017 4097 XM_029336818.2 1871 2027 1156 2746 2557 Q3T0M7 1.14e-45 Ran-specific GTPase-activating protein (Ran-binding protein 1) (RanBP1) Bos taurus (Bovine) nucleocytoplasmic transport [GO:0006913]; positive regulation of mitotic centrosome separation [GO:0046604]; spindle organization [GO:0007051] GO:0005096; GO:0005643; GO:0005737; GO:0005813; GO:0005829; GO:0006913; GO:0007051; GO:0046604 4098 XM_044314961.1 0 21 0 3 80 NA NA NA NA NA NA 4099 XR_006392454.1 51 47 18 22 0 Q99570 1.62e-22 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 4100 XR_006392454.1 51 47 18 22 0 Q99570 1.62e-22 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 4101 XM_044324314.1 19 3 0 17 47 Q9CX47 3.8e-52 DNA repair protein XRCC2 (X-ray repair cross-complementing protein 2) Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; centrosome cycle [GO:0007098]; DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; in utero embryonic development [GO:0001701]; mitotic cell cycle [GO:0000278]; multicellular organism growth [GO:0035264]; negative regulation of neuron apoptotic process [GO:0043524]; neurogenesis [GO:0022008]; positive regulation of neurogenesis [GO:0050769]; regulation of fibroblast apoptotic process [GO:2000269]; response to gamma radiation [GO:0010332]; response to X-ray [GO:0010165]; somitogenesis [GO:0001756]; strand invasion [GO:0042148] GO:0000278; GO:0000400; GO:0000724; GO:0001701; GO:0001756; GO:0005524; GO:0005654; GO:0005657; GO:0005813; GO:0006281; GO:0006974; GO:0007098; GO:0010165; GO:0010332; GO:0022008; GO:0033063; GO:0035264; GO:0042148; GO:0043231; GO:0043524; GO:0050769; GO:0140664; GO:2000269 4102 XM_029338238.2 260 269 247 379 277 NA NA NA NA NA NA 4103 XM_044312855.1 252 256 173 194 152 A7S8T5 4.96e-175 Coiled-coil domain-containing protein 42 homolog Nematostella vectensis (Starlet sea anemone) NA NA 4104 XR_006391745.1 0 0 29 0 0 NA NA NA NA NA NA 4105 XM_044321387.1 582 359 279 476 787 C4A0D9 8.04e-119 Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1-associated protein 1) Branchiostoma floridae (Florida lancelet) (Amphioxus) chromatin organization [GO:0006325]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; negative regulation of DNA-templated transcription [GO:0045892]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; regulation of cell cycle [GO:0051726]; regulation of cell growth [GO:0001558]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0001558; GO:0003682; GO:0004843; GO:0005634; GO:0005737; GO:0006325; GO:0006511; GO:0016579; GO:0035517; GO:0035522; GO:0045892; GO:0051726; GO:0071108 4106 XM_029335226.2 1013 467 19 128 1 Q6GM82 0 Alanine aminotransferase 2 (ALT2) (EC 2.6.1.2) (Glutamate pyruvate transaminase 2) (GPT 2) (Glutamic--alanine transaminase 2) (Glutamic--pyruvic transaminase 2) Xenopus laevis (African clawed frog) 2-oxoglutarate metabolic process [GO:0006103]; biosynthetic process [GO:0009058]; L-alanine catabolic process [GO:0042853]; L-alanine metabolic process [GO:0042851] GO:0004021; GO:0006103; GO:0009058; GO:0030170; GO:0042851; GO:0042853 4107 XM_029334037.2 26 9 0 4 7 Q61184 5.59e-25 Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor) Mus musculus (Mouse) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; circadian rhythm [GO:0007623]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of insulin secretion [GO:0046676] GO:0004930; GO:0005886; GO:0007186; GO:0007193; GO:0007623; GO:0008502; GO:0042562; GO:0043025; GO:0043235; GO:0046676; GO:0097159 4108 XM_044307859.1 474 8 31 29 7 NA NA NA NA NA NA 4109 XM_029326529.2 0 45 0 23 22 Q69Z28 7.67e-158 A disintegrin and metalloproteinase with thrombospondin motifs 16 (ADAM-TS 16) (ADAM-TS16) (ADAMTS-16) (EC 3.4.24.-) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; extracellular matrix organization [GO:0030198]; male gamete generation [GO:0048232]; proteolysis [GO:0006508]; regulation of cilium assembly [GO:1902017]; regulation of systemic arterial blood pressure [GO:0003073] GO:0001658; GO:0003073; GO:0004222; GO:0005576; GO:0006508; GO:0030198; GO:0031012; GO:0046872; GO:0048232; GO:1902017 4110 XM_044323599.1 2 15 1 19 8 P19579 9.24e-32 Capsule biosynthesis protein CapA Bacillus anthracis capsule polysaccharide biosynthetic process [GO:0045227] GO:0005886; GO:0045227 4111 XM_044313065.1 6 13 0 6 7 Q80XJ3 1.14e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 4112 XR_006393230.1 5 3 12 43 4 NA NA NA NA NA NA 4113 XM_029349877.2 3344 2479 1472 3015 2808 Q8K021 1.12e-64 Secretory carrier-associated membrane protein 1 (Secretory carrier membrane protein 1) Mus musculus (Mouse) endocytosis [GO:0006897]; establishment of localization in cell [GO:0051649]; exocytosis [GO:0006887]; protein transport [GO:0015031] GO:0005802; GO:0006887; GO:0006897; GO:0008021; GO:0015031; GO:0016020; GO:0019904; GO:0030136; GO:0030659; GO:0030672; GO:0032588; GO:0042589; GO:0045202; GO:0051649; GO:0055038 4114 XM_044308556.1 0 0 0 6 25 Q9ES08 4.86e-24 Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3) (Two pore potassium channel KT3.2) (Two pore K(+) channel KT3.2) Rattus norvegicus (Rat) potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of ion transmembrane transport [GO:0034765]; stabilization of membrane potential [GO:0030322] GO:0005249; GO:0005267; GO:0005886; GO:0006813; GO:0008021; GO:0015271; GO:0022841; GO:0030322; GO:0034765; GO:0071805; GO:1990573 4115 XR_003824627.2 7 0 4 3 1 NA NA NA NA NA NA 4116 XR_006395956.1 30 3 0 0 0 NA NA NA NA NA NA 4117 XM_044320512.1 6 5 10 36 23 NA NA NA NA NA NA 4118 XM_029343190.2 886 1095 414 541 768 NA NA NA NA NA NA 4119 XR_006395994.1 92 123 51 122 100 Q8IS64 1.03e-142 Endothelin-converting enzyme homolog (ECE) (EC 3.4.24.-) Locusta migratoria (Migratory locust) proteolysis [GO:0006508] GO:0004175; GO:0004222; GO:0005886; GO:0006508; GO:0008270 4120 XM_044325163.1 0 3 0 11 45 NA NA NA NA NA NA 4121 XM_044321201.1 8 13 38 26 43 NA NA NA NA NA NA 4122 XR_006397274.1 624 383 433 674 634 NA NA NA NA NA NA 4123 XM_029325334.2 69 12 134 0 126 NA NA NA NA NA NA 4124 XM_029334469.2 58 0 11 19 50 Q6DKN2 1.7e-31 Homeobox protein OTX2-B (xOTX2-B) (Orthodenticle 2-B) (Orthodenticle-A-like protein B) Xenopus laevis (African clawed frog) NA GO:0000981; GO:0003677; GO:0005634 4125 XM_029324621.2 0 0 23 21 3 NA NA NA NA NA NA 4126 XM_044318043.1 193 0 217 14 48 Q96C11 0 FGGY carbohydrate kinase domain-containing protein (D-ribulokinase FGGY) (EC 2.7.1.47) Homo sapiens (Human) carbohydrate phosphorylation [GO:0046835]; neuron cellular homeostasis [GO:0070050]; pentose metabolic process [GO:0019321] GO:0005737; GO:0019150; GO:0019321; GO:0046835; GO:0070050 4127 XM_029333949.2 230 132 116 203 277 NA NA NA NA NA NA 4128 XM_044319352.1 119 81 235 681 34 NA NA NA NA NA NA 4129 XM_029341287.2 0 310 0 0 0 NA NA NA NA NA NA 4130 XM_044324632.1 0 0 0 7 1 NA NA NA NA NA NA 4131 XM_044319078.1 591 317 284 585 443 O62852 5.19e-73 Short transient receptor potential channel 5 (Rtrp5) (TrpC5) (Capacitative calcium entry channel 2) (CCE2) Oryctolagus cuniculus (Rabbit) neuron apoptotic process [GO:0051402]; phosphatidylserine exposure on apoptotic cell surface [GO:0070782] GO:0005262; GO:0005886; GO:0034704; GO:0051402; GO:0070679; GO:0070782 4132 XM_044320211.1 1 0 0 0 150 NA NA NA NA NA NA 4133 XM_044323178.1 6 0 0 5 0 NA NA NA NA NA NA 4134 XM_029329853.2 61 46 51 64 23 NA NA NA NA NA NA 4135 XM_044328417.1 0 51 6 1 0 NA NA NA NA NA NA 4136 XM_029351269.2 0 0 0 16 40 NA NA NA NA NA NA 4137 XM_044314560.1 80 143 97 75 38 NA NA NA NA NA NA 4138 XM_029336554.2 323 392 201 436 474 Q9VCX3 2.79e-34 Probable 39S ribosomal protein L45, mitochondrial (L45mt) (MRP-L45) Drosophila melanogaster (Fruit fly) mitochondrial translation [GO:0032543] GO:0003735; GO:0005739; GO:0005762; GO:0032543 4139 XR_006392995.1 41 2 25 5 151 NA NA NA NA NA NA 4140 XR_003823454.2 140 25 46 74 109 NA NA NA NA NA NA 4141 XM_029357126.2 9 60 44 24 33 NA NA NA NA NA NA 4142 XM_044318137.1 48 31 33 134 189 Q8IYB1 2.28e-21 Nucleotidyltransferase MB21D2 (EC 2.7.7.-) (Mab-21 domain-containing protein 2) (hMB21D2) Homo sapiens (Human) NA GO:0016779; GO:0044877; GO:0045296 4143 XM_044314598.1 525 228 320 307 507 Q4KLT0 3.17e-44 E3 ubiquitin-protein ligase RNF217 (EC 2.3.2.31) (RING finger protein 217) Xenopus laevis (African clawed frog) NA GO:0004842; GO:0005737; GO:0016020; GO:0046872 4144 XM_029337595.2 1039 817 449 907 883 P21670 7.98e-147 Proteasome subunit alpha type-4 (Macropain subunit C9) (Multicatalytic endopeptidase complex subunit C9) (Proteasome component C9) (Proteasome subunit L) Rattus norvegicus (Rat) proteasomal protein catabolic process [GO:0010498]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000502; GO:0000932; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005839; GO:0006511; GO:0010498; GO:0019773 4145 XM_044322661.1 237 203 145 103 57 NA NA NA NA NA NA 4146 XM_044323993.1 644 1278 493 26 28 Q7L1S5 2.72e-41 Carbohydrate sulfotransferase 9 (EC 2.8.2.-) (GalNAc-4-O-sulfotransferase 2) (GalNAc-4-ST2) (GalNAc4ST-2) (N-acetylgalactosamine-4-O-sulfotransferase 2) Homo sapiens (Human) carbohydrate biosynthetic process [GO:0016051]; chondroitin sulfate biosynthetic process [GO:0030206]; glycosaminoglycan metabolic process [GO:0030203]; hormone biosynthetic process [GO:0042446]; proteoglycan biosynthetic process [GO:0030166]; sulfur compound metabolic process [GO:0006790] GO:0000139; GO:0001537; GO:0005576; GO:0006790; GO:0008146; GO:0016020; GO:0016051; GO:0030166; GO:0030203; GO:0030206; GO:0042446; GO:0047756 4147 XR_006397323.1 1000 600 134 64 186 NA NA NA NA NA NA 4148 XM_029348854.2 209 112 80 0 0 O75081 5.59e-131 Protein CBFA2T3 (MTG8-related protein 2) (Myeloid translocation gene on chromosome 16 protein) (hMTG16) (Zinc finger MYND domain-containing protein 4) Homo sapiens (Human) granulocyte differentiation [GO:0030851]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of glycolytic process [GO:0045820]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; regulation of aerobic respiration [GO:1903715]; response to hypoxia [GO:0001666] GO:0000139; GO:0001666; GO:0003714; GO:0005634; GO:0005654; GO:0005730; GO:0008285; GO:0030851; GO:0032436; GO:0045820; GO:0045892; GO:0046872; GO:1903715 4149 XM_029343139.2 55 90 40 144 39 O14649 3.98e-35 Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1) (Two pore K(+) channel KT3.1) Homo sapiens (Human) brain development [GO:0007420]; cellular response to hypoxia [GO:0071456]; cellular response to zinc ion [GO:0071294]; chemical synaptic transmission [GO:0007268]; cochlea development [GO:0090102]; ion transmembrane transport [GO:0034220]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; positive regulation of voltage-gated potassium channel activity [GO:1903818]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of resting membrane potential [GO:0060075]; response to xenobiotic stimulus [GO:0009410]; stabilization of membrane potential [GO:0030322] GO:0005216; GO:0005252; GO:0005267; GO:0005886; GO:0006813; GO:0007268; GO:0007420; GO:0008022; GO:0009410; GO:0015271; GO:0022841; GO:0030322; GO:0034220; GO:0044548; GO:0045202; GO:0051481; GO:0060075; GO:0071294; GO:0071456; GO:0071805; GO:0090102; GO:1903818 4150 XM_044329004.1 512 357 167 574 671 O14981 0 TATA-binding protein-associated factor 172 (EC 3.6.4.-) (ATP-dependent helicase BTAF1) (B-TFIID transcription factor-associated 170 kDa subunit) (TAF(II)170) (TBP-associated factor 172) (TAF-172) Homo sapiens (Human) negative regulation of chromatin binding [GO:0035562]; negative regulation of DNA-templated transcription [GO:0045892] GO:0003677; GO:0003712; GO:0004386; GO:0005524; GO:0005654; GO:0008094; GO:0016887; GO:0017025; GO:0035562; GO:0043231; GO:0045892; GO:0140658 4151 XM_044310058.1 7 3 1 0 9 NA NA NA NA NA NA 4152 XM_044320015.1 43 31 34 375 187 NA NA NA NA NA NA 4153 XM_044328876.1 0 41 28 6 1 Q08431 1.38e-36 Lactadherin (Breast epithelial antigen BA46) (HMFG) (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (SED1) [Cleaved into: Lactadherin short form; Medin] Homo sapiens (Human) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005576; GO:0005615; GO:0005788; GO:0007155; GO:0007338; GO:0009897; GO:0016020; GO:0043277; GO:0062023; GO:0070062; GO:1903561 4154 XM_044320194.1 104 74 40 27 19 NA NA NA NA NA NA 4155 XM_029328374.2 2 0 1 0 12 NA NA NA NA NA NA 4156 XM_044312275.1 149 29 132 62 841 NA NA NA NA NA NA 4157 XR_006391596.1 105 48 15 326 17 NA NA NA NA NA NA 4158 XM_029352722.2 157 387 108 284 346 Q9VIP7 2.19e-79 Alkaline ceramidase (AlkCDase) (EC 3.5.1.23) (Alkaline N-acylsphingosine amidohydrolase) (Alkaline acylsphingosine deacylase) (Protein brainwashing) Drosophila melanogaster (Fruit fly) brain development [GO:0007420]; ceramide catabolic process [GO:0046514]; regulation of lipid metabolic process [GO:0019216]; sphingolipid metabolic process [GO:0006665] GO:0005783; GO:0006665; GO:0007420; GO:0016020; GO:0017040; GO:0019216; GO:0046514; GO:0046872; GO:0102121 4159 XM_029329006.2 107 0 30 0 172 Q8BG58 1.58e-73 Transmembrane prolyl 4-hydroxylase (P4H-TM) (EC 1.14.11.29) (Hypoxia-inducible factor prolyl hydroxylase 4) (HIF-PH4) (HIF-prolyl hydroxylase 4) (HPH-4) Mus musculus (Mouse) peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; regulation of erythrocyte differentiation [GO:0045646] GO:0004656; GO:0005506; GO:0005509; GO:0005783; GO:0005789; GO:0016706; GO:0018401; GO:0031418; GO:0045646 4160 XR_006397948.1 361 108 240 500 518 Q63HN8 0 E3 ubiquitin-protein ligase RNF213 (EC 2.3.2.27) (EC 3.6.4.-) (ALK lymphoma oligomerization partner on chromosome 17) (E3 ubiquitin-lipopolysaccharide ligase RNF213) (EC 2.3.2.-) (Mysterin) (RING finger protein 213) Homo sapiens (Human) angiogenesis [GO:0001525]; defense response to bacterium [GO:0042742]; immune system process [GO:0002376]; lipid droplet formation [GO:0140042]; lipid ubiquitination [GO:0120323]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; regulation of lipid metabolic process [GO:0019216]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]; xenophagy [GO:0098792] GO:0001525; GO:0002040; GO:0002376; GO:0004842; GO:0005524; GO:0005730; GO:0005737; GO:0005811; GO:0005829; GO:0006511; GO:0016020; GO:0016567; GO:0016887; GO:0019216; GO:0042742; GO:0046872; GO:0051865; GO:0061630; GO:0070534; GO:0098792; GO:0120323; GO:0140042; GO:2000051 4161 XR_006397948.1 361 108 240 500 518 Q63HN8 0 E3 ubiquitin-protein ligase RNF213 (EC 2.3.2.27) (EC 3.6.4.-) (ALK lymphoma oligomerization partner on chromosome 17) (E3 ubiquitin-lipopolysaccharide ligase RNF213) (EC 2.3.2.-) (Mysterin) (RING finger protein 213) Homo sapiens (Human) angiogenesis [GO:0001525]; defense response to bacterium [GO:0042742]; immune system process [GO:0002376]; lipid droplet formation [GO:0140042]; lipid ubiquitination [GO:0120323]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; regulation of lipid metabolic process [GO:0019216]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]; xenophagy [GO:0098792] GO:0001525; GO:0002040; GO:0002376; GO:0004842; GO:0005524; GO:0005730; GO:0005737; GO:0005811; GO:0005829; GO:0006511; GO:0016020; GO:0016567; GO:0016887; GO:0019216; GO:0042742; GO:0046872; GO:0051865; GO:0061630; GO:0070534; GO:0098792; GO:0120323; GO:0140042; GO:2000051 4162 XR_006397948.1 361 108 240 500 518 Q63HN8 0 E3 ubiquitin-protein ligase RNF213 (EC 2.3.2.27) (EC 3.6.4.-) (ALK lymphoma oligomerization partner on chromosome 17) (E3 ubiquitin-lipopolysaccharide ligase RNF213) (EC 2.3.2.-) (Mysterin) (RING finger protein 213) Homo sapiens (Human) angiogenesis [GO:0001525]; defense response to bacterium [GO:0042742]; immune system process [GO:0002376]; lipid droplet formation [GO:0140042]; lipid ubiquitination [GO:0120323]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; regulation of lipid metabolic process [GO:0019216]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]; xenophagy [GO:0098792] GO:0001525; GO:0002040; GO:0002376; GO:0004842; GO:0005524; GO:0005730; GO:0005737; GO:0005811; GO:0005829; GO:0006511; GO:0016020; GO:0016567; GO:0016887; GO:0019216; GO:0042742; GO:0046872; GO:0051865; GO:0061630; GO:0070534; GO:0098792; GO:0120323; GO:0140042; GO:2000051 4163 XR_006397948.1 361 108 240 500 518 Q63HN8 1.19e-95 E3 ubiquitin-protein ligase RNF213 (EC 2.3.2.27) (EC 3.6.4.-) (ALK lymphoma oligomerization partner on chromosome 17) (E3 ubiquitin-lipopolysaccharide ligase RNF213) (EC 2.3.2.-) (Mysterin) (RING finger protein 213) Homo sapiens (Human) angiogenesis [GO:0001525]; defense response to bacterium [GO:0042742]; immune system process [GO:0002376]; lipid droplet formation [GO:0140042]; lipid ubiquitination [GO:0120323]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; regulation of lipid metabolic process [GO:0019216]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]; xenophagy [GO:0098792] GO:0001525; GO:0002040; GO:0002376; GO:0004842; GO:0005524; GO:0005730; GO:0005737; GO:0005811; GO:0005829; GO:0006511; GO:0016020; GO:0016567; GO:0016887; GO:0019216; GO:0042742; GO:0046872; GO:0051865; GO:0061630; GO:0070534; GO:0098792; GO:0120323; GO:0140042; GO:2000051 4164 XR_006397948.1 361 108 240 500 518 Q63HN8 1.54e-30 E3 ubiquitin-protein ligase RNF213 (EC 2.3.2.27) (EC 3.6.4.-) (ALK lymphoma oligomerization partner on chromosome 17) (E3 ubiquitin-lipopolysaccharide ligase RNF213) (EC 2.3.2.-) (Mysterin) (RING finger protein 213) Homo sapiens (Human) angiogenesis [GO:0001525]; defense response to bacterium [GO:0042742]; immune system process [GO:0002376]; lipid droplet formation [GO:0140042]; lipid ubiquitination [GO:0120323]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; regulation of lipid metabolic process [GO:0019216]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]; xenophagy [GO:0098792] GO:0001525; GO:0002040; GO:0002376; GO:0004842; GO:0005524; GO:0005730; GO:0005737; GO:0005811; GO:0005829; GO:0006511; GO:0016020; GO:0016567; GO:0016887; GO:0019216; GO:0042742; GO:0046872; GO:0051865; GO:0061630; GO:0070534; GO:0098792; GO:0120323; GO:0140042; GO:2000051 4165 XR_006397948.1 361 108 240 500 518 Q63HN8 1.54e-30 E3 ubiquitin-protein ligase RNF213 (EC 2.3.2.27) (EC 3.6.4.-) (ALK lymphoma oligomerization partner on chromosome 17) (E3 ubiquitin-lipopolysaccharide ligase RNF213) (EC 2.3.2.-) (Mysterin) (RING finger protein 213) Homo sapiens (Human) angiogenesis [GO:0001525]; defense response to bacterium [GO:0042742]; immune system process [GO:0002376]; lipid droplet formation [GO:0140042]; lipid ubiquitination [GO:0120323]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; regulation of lipid metabolic process [GO:0019216]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]; xenophagy [GO:0098792] GO:0001525; GO:0002040; GO:0002376; GO:0004842; GO:0005524; GO:0005730; GO:0005737; GO:0005811; GO:0005829; GO:0006511; GO:0016020; GO:0016567; GO:0016887; GO:0019216; GO:0042742; GO:0046872; GO:0051865; GO:0061630; GO:0070534; GO:0098792; GO:0120323; GO:0140042; GO:2000051 4166 XR_006397948.1 361 108 240 500 518 Q63HN8 1.54e-30 E3 ubiquitin-protein ligase RNF213 (EC 2.3.2.27) (EC 3.6.4.-) (ALK lymphoma oligomerization partner on chromosome 17) (E3 ubiquitin-lipopolysaccharide ligase RNF213) (EC 2.3.2.-) (Mysterin) (RING finger protein 213) Homo sapiens (Human) angiogenesis [GO:0001525]; defense response to bacterium [GO:0042742]; immune system process [GO:0002376]; lipid droplet formation [GO:0140042]; lipid ubiquitination [GO:0120323]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; regulation of lipid metabolic process [GO:0019216]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]; xenophagy [GO:0098792] GO:0001525; GO:0002040; GO:0002376; GO:0004842; GO:0005524; GO:0005730; GO:0005737; GO:0005811; GO:0005829; GO:0006511; GO:0016020; GO:0016567; GO:0016887; GO:0019216; GO:0042742; GO:0046872; GO:0051865; GO:0061630; GO:0070534; GO:0098792; GO:0120323; GO:0140042; GO:2000051 4167 XM_044319918.1 0 41 0 0 112 Q9H7H0 3.82e-67 Methyltransferase-like protein 17, mitochondrial (EC 2.1.1.-) (False p73 target gene protein) (Methyltransferase 11 domain-containing protein 1) (Protein RSM22 homolog, mitochondrial) Homo sapiens (Human) methylation [GO:0032259]; ribosomal small subunit biogenesis [GO:0042274]; translation [GO:0006412] GO:0005654; GO:0005759; GO:0006412; GO:0008168; GO:0032259; GO:0042274; GO:1904047 4168 XM_044328804.1 2 0 0 19 6 NA NA NA NA NA NA 4169 XM_044328580.1 69 0 79 44 23 Q95LR0 4.55e-73 Cilia- and flagella-associated protein 91 (CFAP91) (AMY-1-associating protein expressed in testis 1) (AAT-1) (MYCBP/AMY-1-associated testis-expressed protein 1) (Protein MAATS1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) axonemal central apparatus assembly [GO:1904158]; cell differentiation [GO:0030154]; cilium movement [GO:0003341]; spermatogenesis [GO:0007283] GO:0003341; GO:0005739; GO:0005930; GO:0007283; GO:0030154; GO:0031514; GO:1904158 4170 XM_044328580.1 69 0 79 44 23 Q95LR0 4.55e-73 Cilia- and flagella-associated protein 91 (CFAP91) (AMY-1-associating protein expressed in testis 1) (AAT-1) (MYCBP/AMY-1-associated testis-expressed protein 1) (Protein MAATS1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) axonemal central apparatus assembly [GO:1904158]; cell differentiation [GO:0030154]; cilium movement [GO:0003341]; spermatogenesis [GO:0007283] GO:0003341; GO:0005739; GO:0005930; GO:0007283; GO:0030154; GO:0031514; GO:1904158 4171 XM_029340890.2 1273 689 668 1002 1109 Q28FF3 1.26e-91 Solute carrier family 49 member A3 (Major facilitator superfamily domain-containing protein 7-a) (Major facilitator superfamily domain-containing protein 7-b) (Myosin light polypeptide 5 regulatory protein) (MYL5) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0016020; GO:0022857 4172 XM_044318480.1 72 165 152 80 128 Q9UKT8 9.04e-150 F-box/WD repeat-containing protein 2 (F-box and WD-40 domain-containing protein 2) (Protein MD6) Homo sapiens (Human) protein modification process [GO:0036211]; proteolysis [GO:0006508] GO:0004842; GO:0005829; GO:0006508; GO:0036211 4173 XM_029332327.2 193 316 101 321 574 A7YVD7 4.18e-105 NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 Bos taurus (Bovine) biosynthetic process [GO:0009058]; mitochondrial respiratory chain complex I assembly [GO:0032981] GO:0005739; GO:0005743; GO:0009058; GO:0032981 4174 XM_044310304.1 0 1 1 5 12 P81274 4.92e-25 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 4175 XM_044310304.1 0 1 1 5 12 P81274 1.62e-21 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 4176 XM_044311899.1 0 15 31 65 5 NA NA NA NA NA NA 4177 XM_029331451.2 89 169 330 322 239 J7GQ11 1.74e-66 L-tyrosine decarboxylase (TDC) (EC 4.1.1.25) Levilactobacillus brevis (Lactobacillus brevis) carboxylic acid metabolic process [GO:0019752] GO:0004837; GO:0019752; GO:0030170; GO:0036468 4178 XM_044307580.1 578 462 368 745 858 Q9BY12 2.64e-109 S phase cyclin A-associated protein in the endoplasmic reticulum (S phase cyclin A-associated protein in the ER) (Zinc finger protein 291) Homo sapiens (Human) antral ovarian follicle growth [GO:0001547]; retina development in camera-type eye [GO:0060041]; seminiferous tubule development [GO:0072520]; spermatogenesis [GO:0007283] GO:0001547; GO:0003676; GO:0005654; GO:0005783; GO:0005829; GO:0007283; GO:0008270; GO:0016607; GO:0060041; GO:0061827; GO:0072520; GO:1990917 4179 XM_044307580.1 578 462 368 745 858 Q9BY12 2.36e-85 S phase cyclin A-associated protein in the endoplasmic reticulum (S phase cyclin A-associated protein in the ER) (Zinc finger protein 291) Homo sapiens (Human) antral ovarian follicle growth [GO:0001547]; retina development in camera-type eye [GO:0060041]; seminiferous tubule development [GO:0072520]; spermatogenesis [GO:0007283] GO:0001547; GO:0003676; GO:0005654; GO:0005783; GO:0005829; GO:0007283; GO:0008270; GO:0016607; GO:0060041; GO:0061827; GO:0072520; GO:1990917 4180 XM_029357612.2 400 570 465 678 386 Q5XX13 5.75e-152 F-box/WD repeat-containing protein 10 (F-box and WD-40 domain-containing protein 10) (Ubiquitin ligase-specificity factor) Homo sapiens (Human) NA GO:0005829 4181 XM_044311791.1 0 0 0 0 15 NA NA NA NA NA NA 4182 XM_029354463.2 0 0 0 0 10 NA NA NA NA NA NA 4183 XM_044327241.1 67 42 27 41 41 P08953 4.64e-66 Protein toll Drosophila melanogaster (Fruit fly) antifungal innate immune response [GO:0061760]; cell adhesion [GO:0007155]; cell competition in a multicellular organism [GO:0035212]; defense response to Gram-positive bacterium [GO:0050830]; defense response to oomycetes [GO:0002229]; detection of virus [GO:0009597]; dorsal/ventral axis specification [GO:0009950]; heart development [GO:0007507]; innate immune response [GO:0045087]; larval somatic muscle development [GO:0007526]; negative regulation of cell growth [GO:0030308]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of multicellular organism growth [GO:0040015]; positive regulation of antifungal peptide production [GO:0002804]; positive regulation of antimicrobial peptide production [GO:0002225]; positive regulation of hemocyte proliferation [GO:0035208]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of embryonic pattern specification [GO:1902875]; response to tumor cell [GO:0002347]; response to wounding [GO:0009611]; synapse assembly [GO:0007416]; synaptic target inhibition [GO:0016201]; Toll signaling pathway [GO:0008063]; toll-like receptor signaling pathway [GO:0002224] GO:0002224; GO:0002225; GO:0002229; GO:0002347; GO:0002804; GO:0004888; GO:0004896; GO:0005769; GO:0005886; GO:0007155; GO:0007416; GO:0007507; GO:0007526; GO:0008063; GO:0009597; GO:0009611; GO:0009897; GO:0009950; GO:0009986; GO:0016201; GO:0019955; GO:0030308; GO:0032154; GO:0035208; GO:0035212; GO:0038023; GO:0040015; GO:0042802; GO:0045087; GO:0045944; GO:0046627; GO:0046790; GO:0050135; GO:0050830; GO:0061760; GO:0061809; GO:0070976; GO:1902875 4184 XR_003828582.2 16 2 7 10 18 NA NA NA NA NA NA 4185 XM_044316948.1 64 37 43 42 33 NA NA NA NA NA NA 4186 XM_029338317.2 117 164 83 169 104 Q9UDY8 1.01e-65 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (EC 3.4.22.-) (MALT lymphoma-associated translocation) (Paracaspase) Homo sapiens (Human) activation of NF-kappaB-inducing kinase activity [GO:0007250]; B cell activation [GO:0042113]; B-1 B cell differentiation [GO:0001923]; defense response [GO:0006952]; innate immune response [GO:0045087]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; negative regulation of apoptotic process [GO:0043066]; nuclear export [GO:0051168]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T-helper 17 cell differentiation [GO:2000321]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of apoptotic process [GO:0042981]; regulation of T cell receptor signaling pathway [GO:0050856]; response to fungus [GO:0009620]; T cell proliferation [GO:0042098]; T cell receptor signaling pathway [GO:0050852] GO:0001650; GO:0001923; GO:0002020; GO:0002096; GO:0002726; GO:0004175; GO:0004197; GO:0004842; GO:0005634; GO:0005737; GO:0005829; GO:0006508; GO:0006952; GO:0007250; GO:0008233; GO:0009620; GO:0031398; GO:0031663; GO:0032449; GO:0032731; GO:0032743; GO:0032991; GO:0036094; GO:0042098; GO:0042113; GO:0042802; GO:0042981; GO:0043066; GO:0043123; GO:0043280; GO:0043621; GO:0045087; GO:0048471; GO:0050852; GO:0050856; GO:0051092; GO:0051168; GO:0051603; GO:2000321 4187 XR_006392081.1 539 304 255 667 701 NA NA NA NA NA NA 4188 XM_029325139.2 186 164 156 227 59 Q8C206 3.05e-36 G-protein coupled receptor 157 Mus musculus (Mouse) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; circadian behavior [GO:0048512]; G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; radial glial cell differentiation [GO:0060019] GO:0004930; GO:0005886; GO:0007166; GO:0007186; GO:0007189; GO:0048512; GO:0051482; GO:0060019; GO:0060170 4189 XM_029345873.2 67 0 0 0 104 NA NA NA NA NA NA 4190 XM_029352279.2 1049 633 840 931 769 P97846 3.28e-32 Contactin-associated protein 1 (Caspr) (Caspr1) (Neurexin IV) (Neurexin-4) (Paranodin) (p190) Rattus norvegicus (Rat) axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cytoskeleton organization [GO:0007010]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process [GO:0050905]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuronal action potential propagation [GO:0019227]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; postsynaptic density organization [GO:0097106]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; regulation of synapse maturation [GO:0090128] GO:0002175; GO:0007005; GO:0007010; GO:0007155; GO:0007409; GO:0016020; GO:0017124; GO:0019227; GO:0022010; GO:0022011; GO:0030424; GO:0030913; GO:0031175; GO:0033010; GO:0033270; GO:0042552; GO:0048786; GO:0048812; GO:0050884; GO:0050885; GO:0050905; GO:0071205; GO:0090128; GO:0097106; GO:0098529; GO:0098978; GO:1990227 4191 XR_003824276.2 408 248 116 92 251 NA NA NA NA NA NA 4192 XM_029339951.2 35 6 42 29 22 NA NA NA NA NA NA 4193 XM_044325422.1 0 0 0 11 0 NA NA NA NA NA NA 4194 XM_029345310.2 71 0 50 4 42 Q92113 2e-139 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Squalus acanthias (Spiny dogfish) steroid biosynthetic process [GO:0006694] GO:0004508; GO:0005506; GO:0006694; GO:0016020; GO:0020037; GO:0047442 4195 XM_029349676.2 10 0 11 6 53 NA NA NA NA NA NA 4196 XM_029329934.2 12 16 13 23 44 P19984 3.55e-21 Profilin-2 (Basic profilin) (Profilin II) Acanthamoeba castellanii (Amoeba) NA GO:0003779; GO:0005737; GO:0005856 4197 XM_029325022.2 0 201 0 70 1 Q9ULR3 3.64e-118 Protein phosphatase 1H (EC 3.1.3.16) Homo sapiens (Human) protein dephosphorylation [GO:0006470] GO:0004721; GO:0005634; GO:0005654; GO:0005737; GO:0006470; GO:0017018; GO:0042802; GO:0098978 4198 XM_044326235.1 353 844 139 1 318 NA NA NA NA NA NA 4199 XM_044323484.1 561 1369 261 937 1059 B7WFQ1 0 Uncharacterized skeletal organic matrix protein 2 (Uncharacterized SOMP-2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 4200 XR_006397918.1 1391 906 809 34 1576 A0A0R4IBK5 0 E3 ubiquitin-protein ligase rnf213-alpha (EC 2.3.2.27) (EC 3.6.4.-) (E3 ubiquitin-lipopolysaccharide ligase rnf213-alpha) (EC 2.3.2.-) (Mysterin-A) (Mysterin-alpha) (RING finger protein 213-A) (RING finger protein 213-alpha) Danio rerio (Zebrafish) (Brachydanio rerio) blood circulation [GO:0008015]; defense response to bacterium [GO:0042742]; immune system process [GO:0002376]; lipid droplet formation [GO:0140042]; lipid ubiquitination [GO:0120323]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein K63-linked ubiquitination [GO:0070534]; regulation of lipid metabolic process [GO:0019216]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]; xenophagy [GO:0098792] GO:0002040; GO:0002376; GO:0004842; GO:0005524; GO:0005730; GO:0005811; GO:0005829; GO:0006511; GO:0008015; GO:0016887; GO:0019216; GO:0042742; GO:0046872; GO:0061630; GO:0070534; GO:0098792; GO:0120323; GO:0140042; GO:2000051 4201 XR_006397918.1 1391 906 809 34 1576 A0A0R4IBK5 2.37e-110 E3 ubiquitin-protein ligase rnf213-alpha (EC 2.3.2.27) (EC 3.6.4.-) (E3 ubiquitin-lipopolysaccharide ligase rnf213-alpha) (EC 2.3.2.-) (Mysterin-A) (Mysterin-alpha) (RING finger protein 213-A) (RING finger protein 213-alpha) Danio rerio (Zebrafish) (Brachydanio rerio) blood circulation [GO:0008015]; defense response to bacterium [GO:0042742]; immune system process [GO:0002376]; lipid droplet formation [GO:0140042]; lipid ubiquitination [GO:0120323]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein K63-linked ubiquitination [GO:0070534]; regulation of lipid metabolic process [GO:0019216]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]; xenophagy [GO:0098792] GO:0002040; GO:0002376; GO:0004842; GO:0005524; GO:0005730; GO:0005811; GO:0005829; GO:0006511; GO:0008015; GO:0016887; GO:0019216; GO:0042742; GO:0046872; GO:0061630; GO:0070534; GO:0098792; GO:0120323; GO:0140042; GO:2000051 4202 XM_029347087.2 564 469 408 446 555 A7SWD3 7.94e-103 Glucose-induced degradation protein 8 homolog Nematostella vectensis (Starlet sea anemone) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; Wnt signaling pathway [GO:0016055] GO:0005634; GO:0005737; GO:0016055; GO:0043161 4203 XM_029351747.2 25 25 16 62 0 NA NA NA NA NA NA 4204 XM_029352717.2 0 0 245 599 0 NA NA NA NA NA NA 4205 XM_029337943.2 23 4 3 11 13 NA NA NA NA NA NA 4206 XM_044313734.1 0 4 18 0 3 P04323 8.2e-62 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 4207 XM_029345035.2 603 585 376 751 266 NA NA NA NA NA NA 4208 XM_029334019.2 0 1 0 369 65 NA NA NA NA NA NA 4209 XM_029355360.2 10 21 0 0 9 NA NA NA NA NA NA 4210 XM_029333474.2 394 243 476 372 530 NA NA NA NA NA NA 4211 XM_029338101.2 1809 1505 894 2285 2237 O14974 6.48e-80 Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit) Homo sapiens (Human) cellular response to xenobiotic stimulus [GO:0071466]; centrosome cycle [GO:0007098]; mitotic cell cycle [GO:0000278]; negative regulation of catalytic activity [GO:0043086]; positive regulation of myosin-light-chain-phosphatase activity [GO:0035508]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of myosin-light-chain-phosphatase activity [GO:0035507]; regulation of nucleocytoplasmic transport [GO:0046822]; signal transduction [GO:0007165] GO:0000278; GO:0000776; GO:0004857; GO:0005654; GO:0005730; GO:0005737; GO:0005813; GO:0005829; GO:0005886; GO:0005925; GO:0006470; GO:0007098; GO:0007165; GO:0015629; GO:0019208; GO:0019901; GO:0030018; GO:0030155; GO:0031672; GO:0035507; GO:0035508; GO:0043086; GO:0043292; GO:0045944; GO:0046822; GO:0071466; GO:0071889; GO:0072357 4212 XM_044311194.1 1214 150 237 518 532 Q5TJ56 4.66e-44 Formin-F (Diaphanous-related formin dia1) Dictyostelium discoideum (Social amoeba) 'de novo' actin filament nucleation [GO:0070060]; actin filament polymerization [GO:0030041]; positive phototaxis [GO:0046956] GO:0005522; GO:0015629; GO:0030041; GO:0031143; GO:0031267; GO:0046956; GO:0051015; GO:0070060 4213 XM_044321398.1 16 0 11 1 7 B3EWZ6 6.63e-23 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 4214 XM_044321398.1 16 0 11 1 7 B3EWZ6 1.94e-22 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 4215 XM_044321398.1 16 0 11 1 7 B3EWZ6 2.47e-22 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 4216 XM_044321398.1 16 0 11 1 7 B3EWZ6 2.7e-21 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 4217 XM_044321398.1 16 0 11 1 7 B3EWZ6 3.28e-21 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 4218 XM_044321398.1 16 0 11 1 7 B3EWZ6 3.81e-21 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 4219 XM_029327004.2 20 21 4 17 49 A8MY62 2.02e-42 Putative beta-lactamase-like 1 Homo sapiens (Human) NA NA 4220 XM_044324380.1 169 29 21 45 60 Q96ME1 2.93e-25 F-box/LRR-repeat protein 18 (F-box and leucine-rich repeat protein 18) Homo sapiens (Human) SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0005829; GO:0019005; GO:0031146 4221 XM_044321007.1 50 0 0 0 0 NA NA NA NA NA NA 4222 XM_029330593.2 65 14 172 72 273 O95395 6.95e-62 Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 (EC 2.4.1.102) (EC 2.4.1.148) (EC 2.4.1.150) (C2GnT-mucin type) (C2GnT-M) (hC2GnT-M) (Core 2/core 4 beta-1,6-N-acetylglucosaminyltransferase) (C2/4GnT) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; intestinal absorption [GO:0050892]; kidney morphogenesis [GO:0060993]; O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493]; tissue morphogenesis [GO:0048729] GO:0000139; GO:0003829; GO:0005975; GO:0006493; GO:0008109; GO:0008375; GO:0016020; GO:0016266; GO:0048729; GO:0050892; GO:0060993; GO:0070062; GO:0106325; GO:0106326 4223 XM_044312849.1 2673 2049 1565 2168 1800 Q9JMB7 0 Piwi-like protein 1 (EC 3.1.26.-) Mus musculus (Mouse) meiotic cell cycle [GO:0051321]; negative regulation of transposition [GO:0010529]; piRNA processing [GO:0034587]; regulation of translation [GO:0006417]; RNA-mediated gene silencing [GO:0031047]; sperm DNA condensation [GO:0035092]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283] GO:0003723; GO:0003727; GO:0003729; GO:0004521; GO:0005634; GO:0005737; GO:0005829; GO:0006417; GO:0007283; GO:0007286; GO:0010529; GO:0019901; GO:0031047; GO:0033391; GO:0034584; GO:0034587; GO:0035092; GO:0043186; GO:0046872; GO:0051321; GO:0097433; GO:0140262; GO:1905538 4224 XR_006395088.1 76 92 55 59 50 NA NA NA NA NA NA 4225 XR_003824596.2 29 2 17 1 10 NA NA NA NA NA NA 4226 XR_006392188.1 91 112 99 174 223 NA NA NA NA NA NA 4227 XM_029346279.2 1635 560 529 1549 970 Q6TMK4 1.16e-88 Peroxinectin A (EC 1.11.1.7) Dictyostelium discoideum (Social amoeba) defense response to bacterium [GO:0042742]; hydrogen peroxide catabolic process [GO:0042744]; immune response [GO:0006955]; response to oxidative stress [GO:0006979] GO:0004447; GO:0004601; GO:0005576; GO:0005783; GO:0006955; GO:0006979; GO:0020037; GO:0036393; GO:0042742; GO:0042744; GO:0140825 4228 XM_044315341.1 14 0 0 0 0 NA NA NA NA NA NA 4229 XM_044312976.1 16 29 32 0 10 NA NA NA NA NA NA 4230 XM_044322258.1 21 4 22 53 11 NA NA NA NA NA NA 4231 XM_044321941.1 310 24 76 167 125 NA NA NA NA NA NA 4232 XM_044320982.1 42 0 39 4 60 NA NA NA NA NA NA 4233 XM_044314084.1 0 0 4 7 0 NA NA NA NA NA NA 4234 XM_029345439.2 737 145 2 158 142 B1AJZ9 8.77e-32 Forkhead-associated domain-containing protein 1 (FHA domain-containing protein 1) Homo sapiens (Human) NA NA 4235 XM_029345439.2 737 145 2 158 142 B1AJZ9 1.04e-28 Forkhead-associated domain-containing protein 1 (FHA domain-containing protein 1) Homo sapiens (Human) NA NA 4236 XM_044319940.1 0 0 0 0 24 NA NA NA NA NA NA 4237 XM_029327861.2 8 5 41 0 72 NA NA NA NA NA NA 4238 XR_003828313.2 0 0 0 6 0 NA NA NA NA NA NA 4239 XR_003825316.2 12 17 17 17 33 NA NA NA NA NA NA 4240 XR_006396889.1 3 0 6 8 111 NA NA NA NA NA NA 4241 XM_044308873.1 4 0 2 17 0 NA NA NA NA NA NA 4242 XR_006395409.1 189 147 199 250 440 NA NA NA NA NA NA 4243 XM_044325185.1 37 0 498 0 294 Q32PZ3 0 Protein unc-45 homolog A (Unc-45A) (Smooth muscle cell-associated protein 1) (SMAP-1) Rattus norvegicus (Rat) cell differentiation [GO:0030154]; chaperone-mediated protein folding [GO:0061077]; muscle organ development [GO:0007517] GO:0005634; GO:0005737; GO:0007517; GO:0030154; GO:0048471; GO:0051879; GO:0061077 4244 XM_044319301.1 349 83 99 140 123 NA NA NA NA NA NA 4245 XM_029338226.2 200 275 202 221 122 NA NA NA NA NA NA 4246 XM_029342551.2 1069 664 595 1258 942 NA NA NA NA NA NA 4247 XM_044323054.1 0 144 16 0 0 Q08DY9 2.71e-40 Caspase-3 (CASP-3) (EC 3.4.22.56) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12] Bos taurus (Bovine) positive regulation of amyloid-beta formation [GO:1902004]; proteolysis [GO:0006508]; regulation of protein stability [GO:0031647] GO:0004175; GO:0005737; GO:0006508; GO:0031647; GO:0097153; GO:0097199; GO:0097200; GO:1902004 4248 XM_029346536.2 0 0 0 230 20 P32297 7.41e-93 Neuronal acetylcholine receptor subunit alpha-3 Homo sapiens (Human) acetylcholine receptor signaling pathway [GO:0095500]; activation of transmembrane receptor protein tyrosine kinase activity [GO:0007171]; behavioral response to nicotine [GO:0035095]; chemical synaptic transmission [GO:0007268]; excitatory postsynaptic potential [GO:0060079]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; locomotory behavior [GO:0007626]; membrane depolarization [GO:0051899]; nervous system development [GO:0007399]; nervous system process [GO:0050877]; regulation of acetylcholine secretion, neurotransmission [GO:0014056]; regulation of dendrite morphogenesis [GO:0048814]; regulation of membrane potential [GO:0042391]; regulation of smooth muscle contraction [GO:0006940]; response to acetylcholine [GO:1905144]; signal transduction [GO:0007165]; synaptic transmission involved in micturition [GO:0060084]; synaptic transmission, cholinergic [GO:0007271] GO:0005231; GO:0005886; GO:0005892; GO:0006811; GO:0006940; GO:0007165; GO:0007171; GO:0007268; GO:0007271; GO:0007399; GO:0007626; GO:0014056; GO:0014069; GO:0015276; GO:0015464; GO:0016020; GO:0016607; GO:0022848; GO:0030425; GO:0030594; GO:0034220; GO:0035095; GO:0042166; GO:0042391; GO:0043005; GO:0043025; GO:0044853; GO:0045202; GO:0045211; GO:0048814; GO:0050877; GO:0051899; GO:0060079; GO:0060084; GO:0095500; GO:1904315; GO:1905144 4249 XM_029350746.2 418 329 214 415 315 Q9NRA2 1.13e-141 Sialin (H(+)/nitrate cotransporter) (H(+)/sialic acid cotransporter) (AST) (Membrane glycoprotein HP59) (Solute carrier family 17 member 5) (Vesicular excitatory amino acid transporter) (VEAT) Homo sapiens (Human) amino acid transport [GO:0006865]; anion transport [GO:0006820]; ion transport [GO:0006811]; response to bacterium [GO:0009617]; sialic acid transport [GO:0015739] GO:0005351; GO:0005764; GO:0005765; GO:0005829; GO:0005886; GO:0006811; GO:0006820; GO:0006865; GO:0009617; GO:0015136; GO:0015538; GO:0015739; GO:0016020; GO:0022857; GO:0030672; GO:0042880 4250 XM_029339218.2 366 503 344 372 529 Q2TBI8 2.36e-51 Uridine diphosphate glucose pyrophosphatase NUDT22 (UDPG pyrophosphatase) (UGPPase) (EC 3.6.1.45) (Nucleoside diphosphate-linked moiety X motif 22) (Nudix motif 22) Bos taurus (Bovine) NA GO:0008768; GO:0046872; GO:0052751 4251 XM_029351841.2 1568 909 863 1522 1016 D3UW23 0 Glutamyl aminopeptidase (EAP) (EC 3.4.11.7) (Aminopeptidase A) (AP-A) (Rhiminopeptidase A) Bitis rhinoceros (West African gaboon viper) (Vipera rhinoceros) proteolysis [GO:0006508] GO:0004177; GO:0005886; GO:0006508; GO:0008237; GO:0008270 4252 XR_006395951.1 283 103 69 174 125 NA NA NA NA NA NA 4253 XM_044317691.1 0 0 0 0 25 NA NA NA NA NA NA 4254 XM_044325137.1 275 29 0 18 0 NA NA NA NA NA NA 4255 XM_029346211.2 196 166 90 93 42 NA NA NA NA NA NA 4256 XM_029333252.2 1383 1083 524 1556 1024 NA NA NA NA NA NA 4257 XM_029345363.2 3386 4929 3862 3670 4871 Q8TCT9 1.43e-160 Minor histocompatibility antigen H13 (EC 3.4.23.-) (Intramembrane protease 1) (IMP-1) (IMPAS-1) (hIMP1) (Presenilin-like protein 3) (Signal peptide peptidase) Homo sapiens (Human) in utero embryonic development [GO:0001701]; membrane protein proteolysis [GO:0033619]; membrane protein proteolysis involved in retrograde protein transport, ER to cytosol [GO:1904211]; regulation of heme oxygenase activity [GO:0061960]; signal peptide processing [GO:0006465] GO:0001701; GO:0005783; GO:0005789; GO:0005791; GO:0005886; GO:0006465; GO:0008233; GO:0009986; GO:0016020; GO:0031625; GO:0033619; GO:0036513; GO:0042500; GO:0042803; GO:0061960; GO:0098553; GO:0098554; GO:1904211 4258 XM_044313884.1 0 3 37 19 5 Q09575 2.41e-56 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 4259 XM_044327441.1 167 141 153 81 336 NA NA NA NA NA NA 4260 XR_006391738.1 27 30 6 55 33 NA NA NA NA NA NA 4261 XM_044310192.1 4 24 2 138 13 NA NA NA NA NA NA 4262 XM_029358264.2 1862 1856 2253 2757 2917 NA NA NA NA NA NA 4263 XM_029349437.2 2010 805 998 1920 1725 P70388 0 DNA repair protein RAD50 (mRad50) (EC 3.6.-.-) Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; chromosome organization [GO:0051276]; chromosome organization involved in meiotic cell cycle [GO:0070192]; DNA double-strand break processing [GO:0000729]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA strand resection involved in replication fork processing [GO:0110025]; double-strand break repair [GO:0006302]; homologous recombination [GO:0035825]; mitotic G2/M transition checkpoint [GO:0044818]; negative regulation of telomere capping [GO:1904354]; negative regulation of viral entry into host cell [GO:0046597]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; positive regulation of kinase activity [GO:0033674]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of telomere maintenance [GO:0032206]; regulation of mitotic cell cycle [GO:0007346]; regulation of mitotic recombination [GO:0000019]; telomere maintenance via recombination [GO:0000722]; telomere maintenance via telomerase [GO:0007004]; telomeric 3' overhang formation [GO:0031860] GO:0000014; GO:0000019; GO:0000722; GO:0000729; GO:0000781; GO:0000785; GO:0000794; GO:0003677; GO:0003678; GO:0003690; GO:0003691; GO:0005524; GO:0005634; GO:0005654; GO:0006281; GO:0006302; GO:0006310; GO:0006974; GO:0007004; GO:0007346; GO:0008408; GO:0016234; GO:0016887; GO:0030674; GO:0030870; GO:0031860; GO:0031954; GO:0032206; GO:0032508; GO:0033674; GO:0035825; GO:0035861; GO:0042802; GO:0043047; GO:0044818; GO:0044877; GO:0045120; GO:0046597; GO:0046872; GO:0048471; GO:0051276; GO:0051880; GO:0070192; GO:0070533; GO:0090305; GO:0098687; GO:0110025; GO:0140664; GO:1904354 4264 XM_029329524.2 120 92 56 70 69 Q49LS8 1.65e-47 XK-related protein 6 Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon nigroviridis) NA GO:0005886 4265 XM_029345581.2 3461 4144 2227 2855 1886 P12815 1.65e-71 Programmed cell death protein 6 (ALG-257) (Apoptosis-linked gene 2 protein) (ALG-2) (PMP41) Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cellular response to heat [GO:0034605]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein monoubiquitination [GO:1902527]; response to calcium ion [GO:0051592]; vascular endothelial growth factor receptor-2 signaling pathway [GO:0036324] GO:0000287; GO:0001525; GO:0001938; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005783; GO:0005789; GO:0005829; GO:0006886; GO:0006888; GO:0006915; GO:0006919; GO:0010595; GO:0014029; GO:0014032; GO:0030127; GO:0030674; GO:0030948; GO:0031410; GO:0031463; GO:0032007; GO:0034605; GO:0036324; GO:0042802; GO:0042803; GO:0043280; GO:0043495; GO:0045766; GO:0046983; GO:0048208; GO:0048306; GO:0051592; GO:0051898; GO:0070971; GO:1902527; GO:1990756 4266 XM_044321721.1 0 70 85 0 0 P54131 8.56e-68 Neuronal acetylcholine receptor subunit alpha-7 Bos taurus (Bovine) calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; cognition [GO:0050890]; ion transmembrane transport [GO:0034220]; negative regulation of tumor necrosis factor production [GO:0032720]; nervous system process [GO:0050877]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAPK cascade [GO:0043410]; regulation of membrane potential [GO:0042391]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271] GO:0001540; GO:0001666; GO:0005231; GO:0005886; GO:0005892; GO:0006816; GO:0006874; GO:0007165; GO:0007268; GO:0007271; GO:0008284; GO:0015464; GO:0015643; GO:0017081; GO:0022848; GO:0030594; GO:0032720; GO:0034220; GO:0035094; GO:0042166; GO:0042391; GO:0042803; GO:0043005; GO:0043410; GO:0045202; GO:0045211; GO:0045766; GO:0050877; GO:0050890; GO:1904315 4267 XM_029338067.2 42 22 0 0 0 NA NA NA NA NA NA 4268 XM_044313263.1 0 0 10 0 0 A0A1L8FDW4 4.54e-49 Peroxisomal targeting signal 1 receptor (PTS1 receptor) (PTS1R) (PTS1-BP) (Peroxin-5) Xenopus laevis (African clawed frog) pexophagy [GO:0000425]; protein import into peroxisome matrix, receptor recycling [GO:0016562]; protein import into peroxisome matrix, substrate release [GO:0044721]; protein import into peroxisome matrix, translocation [GO:0016561] GO:0000425; GO:0005052; GO:0005782; GO:0005829; GO:0016561; GO:0016562; GO:0044721; GO:0140597 4269 XM_044325728.1 136 130 94 246 152 NA NA NA NA NA NA 4270 XM_044326877.1 0 0 10 0 0 NA NA NA NA NA NA 4271 XM_029349318.2 17 2 5 27 0 Q15075 2.52e-37 Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2) Homo sapiens (Human) chemical synaptic transmission, postsynaptic [GO:0099565]; early endosome to late endosome transport [GO:0045022]; endocytosis [GO:0006897]; modulation by host of viral process [GO:0044788]; synaptic vesicle to endosome fusion [GO:0016189]; vesicle fusion [GO:0006906] GO:0005516; GO:0005545; GO:0005737; GO:0005769; GO:0005829; GO:0005969; GO:0006897; GO:0006906; GO:0008270; GO:0016020; GO:0016189; GO:0019897; GO:0030742; GO:0031901; GO:0042803; GO:0044308; GO:0044788; GO:0045022; GO:0070062; GO:0098685; GO:0098794; GO:0098978; GO:0099565 4272 XM_029349318.2 17 2 5 27 0 Q15075 2.52e-37 Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2) Homo sapiens (Human) chemical synaptic transmission, postsynaptic [GO:0099565]; early endosome to late endosome transport [GO:0045022]; endocytosis [GO:0006897]; modulation by host of viral process [GO:0044788]; synaptic vesicle to endosome fusion [GO:0016189]; vesicle fusion [GO:0006906] GO:0005516; GO:0005545; GO:0005737; GO:0005769; GO:0005829; GO:0005969; GO:0006897; GO:0006906; GO:0008270; GO:0016020; GO:0016189; GO:0019897; GO:0030742; GO:0031901; GO:0042803; GO:0044308; GO:0044788; GO:0045022; GO:0070062; GO:0098685; GO:0098794; GO:0098978; GO:0099565 4273 XM_044314306.1 0 0 0 0 27 NA NA NA NA NA NA 4274 XM_029337153.2 888 517 382 706 829 Q1RM03 9.2e-50 Trichoplein keratin filament-binding protein (Protein TCHP) Danio rerio (Zebrafish) (Brachydanio rerio) apoptotic process [GO:0006915] GO:0005737; GO:0006915; GO:0045095 4275 XM_044316712.1 15 15 20 26 41 A7S4N4 2.65e-80 Probable serine incorporator Nematostella vectensis (Starlet sea anemone) phospholipid biosynthetic process [GO:0008654] GO:0005789; GO:0008654; GO:0016020 4276 XM_044312453.1 473 0 163 0 0 Q9NZM1 0 Myoferlin (Fer-1-like protein 3) Homo sapiens (Human) blood circulation [GO:0008015]; membrane fusion [GO:0061025]; muscle contraction [GO:0006936]; plasma membrane organization [GO:0007009]; plasma membrane repair [GO:0001778]; T-tubule organization [GO:0033292] GO:0001778; GO:0005543; GO:0005635; GO:0005886; GO:0005901; GO:0006936; GO:0007009; GO:0008015; GO:0030659; GO:0031410; GO:0031965; GO:0033292; GO:0043231; GO:0046872; GO:0061025; GO:0070062 4277 XM_029332623.2 259 65 65 131 17 P49337 3.52e-67 Protein Wnt-4 Gallus gallus (Chicken) canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; kidney morphogenesis [GO:0060993]; negative regulation of androgen biosynthetic process [GO:2000180]; neuron differentiation [GO:0030182]; positive regulation of cartilage development [GO:0061036]; positive regulation of skeletal muscle cell proliferation [GO:0014858]; positive regulation of skeletal muscle fiber differentiation [GO:1902811] GO:0005109; GO:0005125; GO:0005615; GO:0005737; GO:0014858; GO:0030182; GO:0045165; GO:0060070; GO:0060993; GO:0061036; GO:1902811; GO:2000180 4278 XM_029324946.2 0 7 1 1 10 NA NA NA NA NA NA 4279 XM_044319009.1 838 1931 445 570 480 Q75N73 4.09e-79 Metal cation symporter ZIP14 (Factor for adipocyte differentiation 123) (FAD-123) (Solute carrier family 39 member 14) (Zrt- and Irt-like protein 14) (ZIP-14) Mus musculus (Mouse) cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; cellular zinc ion homeostasis [GO:0006882]; chondrocyte differentiation [GO:0002062]; gluconeogenesis [GO:0006094]; import across plasma membrane [GO:0098739]; inorganic cation transmembrane transport [GO:0098662]; insulin receptor signaling pathway [GO:0008286]; iron import into cell [GO:0033212]; iron ion transmembrane transport [GO:0034755]; iron ion transport [GO:0006826]; manganese ion homeostasis [GO:0055071]; manganese ion transmembrane transport [GO:0071421]; negative regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051344]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; regulation of hormone levels [GO:0010817]; zinc ion import across plasma membrane [GO:0071578]; zinc ion transmembrane transport [GO:0071577]; zinc ion transport [GO:0006829] GO:0002062; GO:0005381; GO:0005384; GO:0005385; GO:0005765; GO:0005886; GO:0006094; GO:0006826; GO:0006829; GO:0006882; GO:0008286; GO:0010817; GO:0015086; GO:0015093; GO:0015296; GO:0016020; GO:0016323; GO:0016324; GO:0031901; GO:0031902; GO:0032869; GO:0033212; GO:0034755; GO:0045745; GO:0051344; GO:0055071; GO:0071333; GO:0071421; GO:0071577; GO:0071578; GO:0098662; GO:0098739 4280 XM_029336359.2 729 652 469 1070 695 Q9Z2L6 6.12e-45 Multiple inositol polyphosphate phosphatase 1 (EC 3.1.3.62) (2,3-bisphosphoglycerate 3-phosphatase) (2,3-BPG phosphatase) (EC 3.1.3.80) (Inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase) (Ins(1,3,4,5)P(4) 3-phosphatase) Mus musculus (Mouse) NA GO:0003993; GO:0005788; GO:0005886; GO:0030351; GO:0030352; GO:0034417; GO:0052745; GO:0052826 4281 XM_029356784.2 126 40 129 51 544 P20825 2.04e-74 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 4282 XM_029349777.2 848 1 84 1418 565 NA NA NA NA NA NA 4283 XM_044327682.1 1119 633 709 907 552 A7SGZ5 2.5e-105 Eukaryotic translation initiation factor 3 subunit K (eIF3k) (eIF-3 p25) Nematostella vectensis (Starlet sea anemone) formation of cytoplasmic translation initiation complex [GO:0001732]; regulation of translational initiation [GO:0006446] GO:0001732; GO:0003723; GO:0003743; GO:0005852; GO:0006446; GO:0016282; GO:0033290; GO:0043022 4284 XM_044317759.1 0 0 18 0 0 Q9NQG7 7.01e-30 BLOC-3 complex member HPS4 (Hermansky-Pudlak syndrome 4 protein) (Light-ear protein homolog) Homo sapiens (Human) blood coagulation [GO:0007596]; hemostasis [GO:0007599]; intracellular transport [GO:0046907]; lysosome organization [GO:0007040]; melanocyte differentiation [GO:0030318]; melanosome assembly [GO:1903232]; platelet dense granule organization [GO:0060155]; positive regulation of eye pigmentation [GO:0048075]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein stabilization [GO:0050821]; protein targeting [GO:0006605]; vesicle-mediated transport [GO:0016192] GO:0005085; GO:0005737; GO:0005764; GO:0005765; GO:0005829; GO:0006605; GO:0007040; GO:0007596; GO:0007599; GO:0016020; GO:0016192; GO:0030318; GO:0031085; GO:0031267; GO:0031410; GO:0042470; GO:0042803; GO:0042827; GO:0046907; GO:0046983; GO:0048075; GO:0050821; GO:0060155; GO:1903232; GO:1903955 4285 XM_044321563.1 42 92 91 56 66 A7T0W1 1.33e-45 Protein UXT homolog Nematostella vectensis (Starlet sea anemone) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000785; GO:0003712; GO:0003714; GO:0006357 4286 XM_044317559.1 46 517 387 980 726 NA NA NA NA NA NA 4287 XM_029347345.2 1523 1056 816 1192 1167 NA NA NA NA NA NA 4288 XR_003828538.2 57 357 216 414 229 NA NA NA NA NA NA 4289 XR_006398095.1 0 0 52 0 63 Q5F408 5.73e-62 Cysteine--tRNA ligase, cytoplasmic (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS) Gallus gallus (Chicken) cysteinyl-tRNA aminoacylation [GO:0006423] GO:0000049; GO:0004817; GO:0005524; GO:0005737; GO:0006423; GO:0046872 4290 XR_006398095.1 0 0 52 0 63 Q5F408 5.73e-62 Cysteine--tRNA ligase, cytoplasmic (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS) Gallus gallus (Chicken) cysteinyl-tRNA aminoacylation [GO:0006423] GO:0000049; GO:0004817; GO:0005524; GO:0005737; GO:0006423; GO:0046872 4291 XM_029344458.2 365 757 199 1038 237 Q6PEC4 4.12e-65 S-phase kinase-associated protein 1 (Cyclin-A/CDK2-associated protein p19) (S-phase kinase-associated protein 1A) (p19A) (p19skp1) Rattus norvegicus (Rat) chromatin remodeling [GO:0006338]; histone H2A monoubiquitination [GO:0035518]; maintenance of protein location in nucleus [GO:0051457]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; protein K48-linked ubiquitination [GO:0070936]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0000209; GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0005921; GO:0006338; GO:0006513; GO:0008013; GO:0016567; GO:0019005; GO:0019904; GO:0031146; GO:0031467; GO:0031519; GO:0035518; GO:0051457; GO:0070936; GO:0097602; GO:1904668; GO:1990444; GO:1990756 4292 XM_044323967.1 190 355 276 73 67 Q810V0 2.58e-86 U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10) Mus musculus (Mouse) rRNA processing [GO:0006364] GO:0005694; GO:0005730; GO:0005732; GO:0006364; GO:0032040; GO:0034457 4293 XM_044307327.1 272 320 199 308 226 NA NA NA NA NA NA 4294 XM_029348298.2 157 125 98 195 177 NA NA NA NA NA NA 4295 XM_029328795.2 6335 5805 2464 4584 4063 Q5U3N5 1.64e-95 Protein phosphatase PTC7 homolog (EC 3.1.3.16) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005739; GO:0005759; GO:0017018; GO:0046872 4296 XM_029336499.2 812 439 355 1136 1245 Q91348 0 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (6PF-2-K/Fru-2,6-P2ase) (PFK/FBPase) (6PF-2-K/Fru-2,6-P2ase liver isozyme) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)] Gallus gallus (Chicken) fructose 2,6-bisphosphate metabolic process [GO:0006003]; fructose metabolic process [GO:0006000] GO:0003873; GO:0004331; GO:0005524; GO:0005829; GO:0006000; GO:0006003; GO:0043540 4297 XR_006393890.1 74 260 63 382 265 NA NA NA NA NA NA 4298 XM_044324055.1 1785 843 911 1598 1212 E1C8P7 0 Cell adhesion molecule DSCAML1 (Down syndrome cell adhesion molecule-like protein 1 homolog) Gallus gallus (Chicken) axon guidance [GO:0007411]; camera-type eye photoreceptor cell differentiation [GO:0060219]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; retina layer formation [GO:0010842]; synapse assembly [GO:0007416] GO:0005886; GO:0007156; GO:0007411; GO:0007416; GO:0010842; GO:0045202; GO:0060219 4299 XM_044324055.1 1785 843 911 1598 1212 E1C8P7 4.02e-37 Cell adhesion molecule DSCAML1 (Down syndrome cell adhesion molecule-like protein 1 homolog) Gallus gallus (Chicken) axon guidance [GO:0007411]; camera-type eye photoreceptor cell differentiation [GO:0060219]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; retina layer formation [GO:0010842]; synapse assembly [GO:0007416] GO:0005886; GO:0007156; GO:0007411; GO:0007416; GO:0010842; GO:0045202; GO:0060219 4300 XR_006396335.1 4 5 0 2 32 NA NA NA NA NA NA 4301 XR_006394867.1 2 3 9 0 12 NA NA NA NA NA NA 4302 XM_029323606.2 1240 712 1037 1802 912 Q8WZA2 0 Rap guanine nucleotide exchange factor 4 (Exchange factor directly activated by cAMP 2) (Exchange protein directly activated by cAMP 2) (EPAC 2) (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) Homo sapiens (Human) adaptive immune response [GO:0002250]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; calcium-ion regulated exocytosis [GO:0017156]; G protein-coupled receptor signaling pathway [GO:0007186]; insulin secretion [GO:0030073]; positive regulation of GTPase activity [GO:0043547]; positive regulation of insulin secretion [GO:0032024]; Ras protein signal transduction [GO:0007265]; regulation of exocytosis [GO:0017157]; regulation of synaptic vesicle cycle [GO:0098693] GO:0002250; GO:0005085; GO:0005096; GO:0005829; GO:0005886; GO:0007186; GO:0007189; GO:0007265; GO:0016020; GO:0017156; GO:0017157; GO:0030073; GO:0030552; GO:0030674; GO:0031267; GO:0032024; GO:0043547; GO:0098686; GO:0098693 4303 XM_029326843.2 1164 874 355 421 481 NA NA NA NA NA NA 4304 XM_044311111.1 10 0 0 7 4 P71359 6.33e-42 ATP-dependent DNA helicase RecQ (EC 3.6.4.12) Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; SOS response [GO:0009432] GO:0003677; GO:0005524; GO:0005694; GO:0005737; GO:0006260; GO:0006281; GO:0006310; GO:0009378; GO:0009432; GO:0016887; GO:0030894; GO:0032508; GO:0043138; GO:0043590 4305 XM_044325659.1 0 151 0 184 0 Q28EM8 1.77e-35 LETM1 domain-containing protein 1 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) mitochondrion organization [GO:0007005] GO:0005741; GO:0005743; GO:0007005; GO:0043022 4306 XM_029343308.2 1709 1182 715 1935 1537 NA NA NA NA NA NA 4307 XR_006393833.1 4 0 0 96 0 NA NA NA NA NA NA 4308 XM_044328129.1 178 12 164 38 45 NA NA NA NA NA NA 4309 XM_044312852.1 353 211 196 222 330 NA NA NA NA NA NA 4310 XM_029357291.2 519 386 339 340 263 Q8K2Y0 3.64e-57 ORC ubiquitin ligase 1 (OBI1) (EC 2.3.2.27) (RING finger protein 219) Mus musculus (Mouse) positive regulation of mRNA splicing, via spliceosome [GO:0048026]; protein autoubiquitination [GO:0051865]; protein monoubiquitination [GO:0006513]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0003682; GO:0004842; GO:0006275; GO:0006513; GO:0046872; GO:0048026; GO:0051865 4311 XR_006391448.1 0 2 0 21 24 NA NA NA NA NA NA 4312 XM_029340115.2 275 31 125 108 93 NA NA NA NA NA NA 4313 XM_029332583.2 415 523 120 635 458 Q5R7Q3 2.94e-127 Magnesium transporter NIPA2 (Non-imprinted in Prader-Willi/Angelman syndrome region protein 2 homolog) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0005769; GO:0005886; GO:0015095 4314 XM_029337596.2 166 227 104 108 150 NA NA NA NA NA NA 4315 XM_029330339.2 194 356 0 562 1024 Q6W2J9 6.47e-42 BCL-6 corepressor (BCoR) Homo sapiens (Human) blastocyst hatching [GO:0001835]; chromatin remodeling [GO:0006338]; heart development [GO:0007507]; negative regulation of bone mineralization [GO:0030502]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of histone H3-K36 methylation [GO:0000415]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of tooth mineralization [GO:0070171]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; protein ubiquitination [GO:0016567]; roof of mouth development [GO:0060021]; specification of axis polarity [GO:0065001] GO:0000122; GO:0000415; GO:0000976; GO:0000977; GO:0001835; GO:0003714; GO:0005634; GO:0005654; GO:0006338; GO:0007507; GO:0016567; GO:0030502; GO:0031072; GO:0042476; GO:0042826; GO:0045892; GO:0051572; GO:0060021; GO:0065001; GO:0070171; GO:0140261; GO:0140297 4316 XM_044327115.1 1598 1219 964 2229 1624 Q8WWQ8 0 Stabilin-2 (FAS1 EGF-like and X-link domain-containing adhesion molecule 2) (Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 2) (FEEL-2) (Hyaluronan receptor for endocytosis) [Cleaved into: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)] Homo sapiens (Human) angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; endocytosis [GO:0006897]; hyaluronan catabolic process [GO:0030214]; receptor-mediated endocytosis [GO:0006898] GO:0001525; GO:0005041; GO:0005044; GO:0005509; GO:0005540; GO:0005829; GO:0005886; GO:0006897; GO:0006898; GO:0007155; GO:0009897; GO:0015035; GO:0030169; GO:0030214; GO:0030666; GO:0042742; GO:0050830 4317 XM_044327115.1 1598 1219 964 2229 1624 Q8WWQ8 0 Stabilin-2 (FAS1 EGF-like and X-link domain-containing adhesion molecule 2) (Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 2) (FEEL-2) (Hyaluronan receptor for endocytosis) [Cleaved into: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)] Homo sapiens (Human) angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; endocytosis [GO:0006897]; hyaluronan catabolic process [GO:0030214]; receptor-mediated endocytosis [GO:0006898] GO:0001525; GO:0005041; GO:0005044; GO:0005509; GO:0005540; GO:0005829; GO:0005886; GO:0006897; GO:0006898; GO:0007155; GO:0009897; GO:0015035; GO:0030169; GO:0030214; GO:0030666; GO:0042742; GO:0050830 4318 XM_044327115.1 1598 1219 964 2229 1624 Q8WWQ8 4.9e-176 Stabilin-2 (FAS1 EGF-like and X-link domain-containing adhesion molecule 2) (Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 2) (FEEL-2) (Hyaluronan receptor for endocytosis) [Cleaved into: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)] Homo sapiens (Human) angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; endocytosis [GO:0006897]; hyaluronan catabolic process [GO:0030214]; receptor-mediated endocytosis [GO:0006898] GO:0001525; GO:0005041; GO:0005044; GO:0005509; GO:0005540; GO:0005829; GO:0005886; GO:0006897; GO:0006898; GO:0007155; GO:0009897; GO:0015035; GO:0030169; GO:0030214; GO:0030666; GO:0042742; GO:0050830 4319 XM_044315386.1 43 0 19 14 183 NA NA NA NA NA NA 4320 XM_044307382.1 0 22 0 29 3 NA NA NA NA NA NA 4321 XM_029350653.2 1716 1288 1034 1745 1466 Q5M868 0 Non-lysosomal glucosylceramidase (NLGase) (EC 3.2.1.45) (Beta-glucocerebrosidase 2) (Beta-glucosidase 2) (Bile acid beta-glucosidase GBA2) (Bile acid glucosyl transferase GBA2) (Cholesterol glucosyltransferase GBA2) (EC 2.4.1.-) (Cholesteryl-beta-glucosidase GBA2) (EC 3.2.1.-) (Glucosylceramidase 2) (Non-lysosomal cholesterol glycosyltransferase) (Non-lysosomal galactosylceramidase) (EC 3.2.1.46) (Non-lysosomal glycosylceramidase) Rattus norvegicus (Rat) bile acid metabolic process [GO:0008206]; carbohydrate metabolic process [GO:0005975]; central nervous system development [GO:0007417]; central nervous system neuron development [GO:0021954]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycoside catabolic process [GO:0016139]; lipid glycosylation [GO:0030259]; regulation of actin filament polymerization [GO:0030833]; regulation of membrane lipid distribution [GO:0097035]; regulation of microtubule polymerization [GO:0031113] GO:0004336; GO:0004348; GO:0005829; GO:0005975; GO:0006680; GO:0007417; GO:0008203; GO:0008206; GO:0008422; GO:0016020; GO:0016139; GO:0019898; GO:0021954; GO:0030259; GO:0030833; GO:0031113; GO:0042406; GO:0046527; GO:0050295; GO:0090498; GO:0097035 4322 XR_003826442.2 9 4 4 8 6 NA NA NA NA NA NA 4323 XM_029324700.2 2716 2633 1330 1744 2330 NA NA NA NA NA NA 4324 XM_044315973.1 0 1 12 9 23 NA NA NA NA NA NA 4325 XM_044328016.1 112 163 131 188 422 Q6AYJ1 2.14e-168 ATP-dependent DNA helicase Q1 (EC 3.6.4.12) (DNA-dependent ATPase Q1) (RecQ protein-like 1) Rattus norvegicus (Rat) DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724] GO:0000724; GO:0003678; GO:0005524; GO:0005634; GO:0005694; GO:0005737; GO:0006268; GO:0006281; GO:0006310; GO:0009378; GO:0016887; GO:0032508; GO:0043138; GO:1990814 4326 XM_044328016.1 112 163 131 188 422 Q6AYJ1 1.02e-129 ATP-dependent DNA helicase Q1 (EC 3.6.4.12) (DNA-dependent ATPase Q1) (RecQ protein-like 1) Rattus norvegicus (Rat) DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724] GO:0000724; GO:0003678; GO:0005524; GO:0005634; GO:0005694; GO:0005737; GO:0006268; GO:0006281; GO:0006310; GO:0009378; GO:0016887; GO:0032508; GO:0043138; GO:1990814 4327 XM_029337321.2 341 66 31 149 191 NA NA NA NA NA NA 4328 XM_044307069.1 413 459 305 416 608 P38942 3.12e-107 4-hydroxybutyrate coenzyme A transferase (EC 2.8.3.-) Clostridium kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680) acetate metabolic process [GO:0006083] GO:0006083; GO:0008775 4329 XM_044318985.1 283 0 108 0 2 P70196 9.74e-85 TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6) Mus musculus (Mouse) activation of NF-kappaB-inducing kinase activity [GO:0007250]; activation of protein kinase activity [GO:0032147]; animal organ morphogenesis [GO:0009887]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; bone remodeling [GO:0046849]; bone resorption [GO:0045453]; cell development [GO:0048468]; cellular response to cytokine stimulus [GO:0071345]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-17-mediated signaling pathway [GO:0097400]; JNK cascade [GO:0007254]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin production [GO:0002637]; response to interleukin-1 [GO:0070555]; signal transduction [GO:0007165]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000122; GO:0000209; GO:0001503; GO:0001701; GO:0001843; GO:0002637; GO:0002726; GO:0004842; GO:0005164; GO:0005634; GO:0005737; GO:0005811; GO:0005829; GO:0005886; GO:0005938; GO:0006955; GO:0006974; GO:0007165; GO:0007249; GO:0007250; GO:0007254; GO:0008270; GO:0009887; GO:0009898; GO:0016567; GO:0019221; GO:0019886; GO:0019901; GO:0030316; GO:0031435; GO:0031624; GO:0031625; GO:0031663; GO:0031666; GO:0031996; GO:0032147; GO:0032735; GO:0032743; GO:0032755; GO:0032813; GO:0032991; GO:0033209; GO:0035631; GO:0042088; GO:0042102; GO:0042475; GO:0042802; GO:0042826; GO:0042981; GO:0043011; GO:0043122; GO:0043123; GO:0043422; GO:0043507; GO:0045453; GO:0045672; GO:0045892; GO:0045944; GO:0046330; GO:0046849; GO:0047485; GO:0048468; GO:0048471; GO:0048661; GO:0050852; GO:0051091; GO:0051092; GO:0051865; GO:0061630; GO:0070498; GO:0070534; GO:0070555; GO:0071222; GO:0071345; GO:0097400; GO:1901224; GO:1904996; GO:2000679 4330 XM_044312719.1 4 2 0 6 5 Q91XP5 5.14e-75 Glycine receptor subunit alpha-3 Mus musculus (Mouse) cellular response to amino acid stimulus [GO:0071230]; cellular response to ethanol [GO:0071361]; cellular response to zinc ion [GO:0071294]; chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; neuropeptide signaling pathway [GO:0007218]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; protein homooligomerization [GO:0051260]; regulation of membrane potential [GO:0042391]; response to amino acid [GO:0043200]; signal transduction [GO:0007165]; synaptic transmission, glycinergic [GO:0060012] GO:0004888; GO:0005231; GO:0005886; GO:0007165; GO:0007218; GO:0007268; GO:0016594; GO:0016934; GO:0016935; GO:0022852; GO:0030425; GO:0030594; GO:0034220; GO:0042391; GO:0042734; GO:0043005; GO:0043200; GO:0043204; GO:0045202; GO:0046872; GO:0050877; GO:0051260; GO:0060012; GO:0071230; GO:0071294; GO:0071361; GO:0098690; GO:0099171; GO:0099634; GO:1902476; GO:1904315 4331 XM_029349105.2 60 9 23 50 111 O60941 1.05e-157 Dystrobrevin beta (DTN-B) (Beta-dystrobrevin) Homo sapiens (Human) neuron differentiation [GO:0030182]; synaptic signaling [GO:0099536] GO:0005634; GO:0005737; GO:0005886; GO:0008270; GO:0009925; GO:0014069; GO:0030182; GO:0030425; GO:0045202; GO:0060077; GO:0099536 4332 XM_044322267.1 11 0 3 0 0 NA NA NA NA NA NA 4333 XM_044324813.1 3 11 0 0 0 NA NA NA NA NA NA 4334 XR_006392527.1 1 79 14 8 9 NA NA NA NA NA NA 4335 XR_006394944.1 0 28 2 0 0 NA NA NA NA NA NA 4336 XM_044325349.1 4 3 28 0 64 P25291 9.07e-23 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 4337 XM_029334983.2 1921 1502 721 1741 1997 NA NA NA NA NA NA 4338 XM_029343247.2 1006 988 724 1052 678 Q6F6U3 1.09e-31 NA NA NA NA 4339 XM_029357191.2 3395 2042 1911 3282 3397 Q28034 6.64e-100 Glucosidase 2 subunit beta (80K-H protein) (Glucosidase II subunit beta) (Protein kinase C substrate 60.1 kDa protein heavy chain) (PKCSH) (Vacuolar system-associated protein 60) (VASAP-60) Bos taurus (Bovine) liver development [GO:0001889]; N-glycan processing [GO:0006491] GO:0001889; GO:0005509; GO:0006491; GO:0016787; GO:0017177; GO:0043231 4340 XR_006395243.1 0 0 8 0 0 NA NA NA NA NA NA 4341 XM_044322728.1 0 14 11 37 3 NA NA NA NA NA NA 4342 XM_044325773.1 10 8 12 24 28 NA NA NA NA NA NA 4343 XM_044326429.1 4 0 0 0 6 NA NA NA NA NA NA 4344 XM_044325512.1 512 170 153 337 514 A6QLU6 5.22e-50 Adhesion G-protein coupled receptor D1 (G-protein coupled receptor 133) Bos taurus (Bovine) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0005886; GO:0007166; GO:0007186; GO:0007189 4345 XM_044321153.1 45 5 41 14 146 Q9VBW3 5.38e-60 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 4346 XM_044310090.1 19 10 24 31 7 Q3UQ28 8.72e-27 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 4347 XM_044310090.1 19 10 24 31 7 Q3UQ28 8.95e-23 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 4348 XR_006396787.1 29 44 43 48 65 NA NA NA NA NA NA 4349 XM_044324586.1 7 0 0 12 23 NA NA NA NA NA NA 4350 XR_006396740.1 697 550 440 525 660 Q9UHP3 1.14e-97 Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.4.19.12) (Deubiquitinating enzyme 25) (USP on chromosome 21) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) Homo sapiens (Human) negative regulation of ERAD pathway [GO:1904293]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; protein modification process [GO:0036211]; proteolysis [GO:0006508]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004197; GO:0004843; GO:0005634; GO:0005783; GO:0005829; GO:0006508; GO:0006511; GO:0008233; GO:0016579; GO:0019783; GO:0031625; GO:0032183; GO:0036211; GO:0043130; GO:0051117; GO:0070536; GO:0071108; GO:1904293 4351 XR_006396740.1 697 550 440 525 660 Q9UHP3 1.14e-97 Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.4.19.12) (Deubiquitinating enzyme 25) (USP on chromosome 21) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) Homo sapiens (Human) negative regulation of ERAD pathway [GO:1904293]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; protein modification process [GO:0036211]; proteolysis [GO:0006508]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004197; GO:0004843; GO:0005634; GO:0005783; GO:0005829; GO:0006508; GO:0006511; GO:0008233; GO:0016579; GO:0019783; GO:0031625; GO:0032183; GO:0036211; GO:0043130; GO:0051117; GO:0070536; GO:0071108; GO:1904293 4352 XR_006396740.1 697 550 440 525 660 Q9UHP3 2.2e-45 Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.4.19.12) (Deubiquitinating enzyme 25) (USP on chromosome 21) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) Homo sapiens (Human) negative regulation of ERAD pathway [GO:1904293]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; protein modification process [GO:0036211]; proteolysis [GO:0006508]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004197; GO:0004843; GO:0005634; GO:0005783; GO:0005829; GO:0006508; GO:0006511; GO:0008233; GO:0016579; GO:0019783; GO:0031625; GO:0032183; GO:0036211; GO:0043130; GO:0051117; GO:0070536; GO:0071108; GO:1904293 4353 XR_006394286.1 0 0 0 7 4 NA NA NA NA NA NA 4354 XM_029348442.2 464 181 363 244 272 NA NA NA NA NA NA 4355 XM_044309482.1 25 64 1 0 28 NA NA NA NA NA NA 4356 XR_006392157.1 6 6 4 7 9 NA NA NA NA NA NA 4357 XR_006393948.1 28 0 0 0 5 NA NA NA NA NA NA 4358 XM_029334630.2 16 36 9 9 0 Q66IB8 4.94e-44 UPF0538 protein C2orf76 homolog Danio rerio (Zebrafish) (Brachydanio rerio) NA NA 4359 XM_044318792.1 1035 770 932 1364 1246 Q96C34 8.81e-71 RUN domain-containing protein 1 Homo sapiens (Human) activation of GTPase activity [GO:0090630]; in utero embryonic development [GO:0001701] GO:0001701; GO:0005096; GO:0090630 4360 XM_044328927.1 0 0 0 43 7 Q15822 3.17e-88 Neuronal acetylcholine receptor subunit alpha-2 Homo sapiens (Human) cellular response to nicotine [GO:0071316]; chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; membrane depolarization [GO:0051899]; modulation of inhibitory postsynaptic potential [GO:0098828]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; response to acetylcholine [GO:1905144]; response to nicotine [GO:0035094]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271] GO:0005231; GO:0005654; GO:0005886; GO:0005892; GO:0006811; GO:0007165; GO:0007268; GO:0007271; GO:0015464; GO:0016020; GO:0022848; GO:0030594; GO:0034220; GO:0035094; GO:0042391; GO:0043005; GO:0045171; GO:0045202; GO:0045211; GO:0050877; GO:0050997; GO:0051899; GO:0071316; GO:0098828; GO:0120111; GO:1901363; GO:1904315; GO:1905144 4361 XM_029338570.2 81 61 41 186 55 Q9NTM9 1.05e-82 Copper homeostasis protein cutC homolog Homo sapiens (Human) copper ion homeostasis [GO:0055070]; copper ion transport [GO:0006825]; protein tetramerization [GO:0051262] GO:0005507; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0006825; GO:0051262; GO:0055070 4362 XM_029333854.2 1097 1323 649 982 994 Q15750 6.98e-110 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 1) (TGF-beta-activated kinase 1-binding protein 1) (TAK1-binding protein 1) Homo sapiens (Human) aorta development [GO:0035904]; cardiac septum development [GO:0003279]; coronary vasculature development [GO:0060976]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; lung development [GO:0030324]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001701; GO:0003007; GO:0003279; GO:0004722; GO:0005634; GO:0005829; GO:0007179; GO:0008047; GO:0010008; GO:0016607; GO:0019209; GO:0030324; GO:0032991; GO:0035904; GO:0043406; GO:0044877; GO:0048273; GO:0060976; GO:0071902 4363 XM_044322466.1 24 3 7 13 16 Q5DU56 5.2e-27 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4364 XM_044322466.1 24 3 7 13 16 Q5DU56 7.37e-25 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4365 XM_044322466.1 24 3 7 13 16 Q5DU56 2.35e-21 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4366 XM_029333643.2 475 629 149 535 590 Q8WV37 2.29e-48 Zinc finger protein 480 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0046872 4367 XM_029333643.2 475 629 149 535 590 Q8WV37 3.44e-41 Zinc finger protein 480 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0046872 4368 XM_029333643.2 475 629 149 535 590 Q8WV37 1.86e-40 Zinc finger protein 480 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0046872 4369 XM_029333643.2 475 629 149 535 590 Q8WV37 3.24e-40 Zinc finger protein 480 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0046872 4370 XM_029333643.2 475 629 149 535 590 Q8WV37 6.2e-39 Zinc finger protein 480 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0046872 4371 XM_029333643.2 475 629 149 535 590 Q8WV37 3.57e-34 Zinc finger protein 480 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0046872 4372 XM_029333643.2 475 629 149 535 590 Q8WV37 4.35e-33 Zinc finger protein 480 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0046872 4373 XM_029333643.2 475 629 149 535 590 Q8WV37 1.78e-26 Zinc finger protein 480 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0046872 4374 XM_044319282.1 495 312 303 462 397 A6H603 1.46e-97 NACHT domain- and WD repeat-containing protein 1 Mus musculus (Mouse) negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of gene expression [GO:0010628] GO:0005524; GO:0005730; GO:0005829; GO:0010628; GO:0032088 4375 XM_029349450.2 4 5 0 1 48 O88572 2.22e-94 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 4376 XM_029349450.2 4 5 0 1 48 O88572 3.2e-86 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 4377 XM_029349450.2 4 5 0 1 48 O88572 3.05e-75 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 4378 XM_029349450.2 4 5 0 1 48 O88572 4.64e-65 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 4379 XM_029349450.2 4 5 0 1 48 O88572 6.58e-58 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 4380 XM_029349450.2 4 5 0 1 48 O88572 4.22e-39 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 4381 XM_029349450.2 4 5 0 1 48 O88572 3.33e-38 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 4382 XM_029349450.2 4 5 0 1 48 O88572 8e-38 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 4383 XM_029349450.2 4 5 0 1 48 O88572 1.99e-36 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 4384 XM_029349450.2 4 5 0 1 48 O88572 8.9e-36 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 4385 XM_029349450.2 4 5 0 1 48 O88572 5.35e-35 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 4386 XM_029349450.2 4 5 0 1 48 O88572 1.69e-33 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 4387 XM_029349450.2 4 5 0 1 48 O88572 1.98e-26 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 4388 XM_029349450.2 4 5 0 1 48 O88572 5.58e-24 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 4389 XR_006397198.1 127 100 112 50 40 NA NA NA NA NA NA 4390 XM_044307641.1 0 10 0 6 0 P98092 5.2e-27 Hemocytin (Humoral lectin) Bombyx mori (Silk moth) cell adhesion [GO:0007155] GO:0007155; GO:0030246 4391 XM_029332748.2 2134 2455 1395 1788 1594 NA NA NA NA NA NA 4392 XM_044328418.1 6 0 5 0 0 NA NA NA NA NA NA 4393 XM_029343463.2 1195 615 430 427 805 Q60HF3 5.55e-36 BLOC-3 complex member HPS1 (Hermansky-Pudlak syndrome 1 protein homolog) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) melanosome assembly [GO:1903232]; vesicle-mediated transport [GO:0016192] GO:0005085; GO:0016192; GO:0031085; GO:1903232 4394 XM_029343463.2 1195 615 430 427 805 Q60HF3 1.24e-27 BLOC-3 complex member HPS1 (Hermansky-Pudlak syndrome 1 protein homolog) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) melanosome assembly [GO:1903232]; vesicle-mediated transport [GO:0016192] GO:0005085; GO:0016192; GO:0031085; GO:1903232 4395 XM_029342817.2 13 74 56 39 68 NA NA NA NA NA NA 4396 XM_044324477.1 2591 1277 489 1108 239 NA NA NA NA NA NA 4397 XM_044323342.1 0 0 0 9 0 Q9H9B1 9.14e-149 Histone-lysine N-methyltransferase EHMT1 (EC 2.1.1.-) (EC 2.1.1.367) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a-like protein 1) (GLP) (GLP1) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Lysine N-methyltransferase 1D) Homo sapiens (Human) chromatin organization [GO:0006325]; DNA methylation [GO:0006306]; facultative heterochromatin formation [GO:0140718]; histone H3-K9 methylation [GO:0051567]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-lysine dimethylation [GO:0018027]; peptidyl-lysine monomethylation [GO:0018026]; positive regulation of cold-induced thermogenesis [GO:0120162]; regulation of embryonic development [GO:0045995]; regulation of histone H3-K9 methylation [GO:0051570] GO:0000122; GO:0000785; GO:0001222; GO:0002039; GO:0005634; GO:0005654; GO:0006306; GO:0006325; GO:0008168; GO:0008270; GO:0016279; GO:0016604; GO:0018024; GO:0018026; GO:0018027; GO:0045892; GO:0045995; GO:0046974; GO:0046976; GO:0051567; GO:0051570; GO:0070742; GO:0120162; GO:0140718; GO:0140947 4398 XM_029336511.2 3167 2333 1735 2849 3049 Q9ERE4 8.31e-124 Golgi phosphoprotein 3 (Coat protein GPP34) (Trans-Golgi protein GMx33) Rattus norvegicus (Rat) asymmetric Golgi ribbon formation [GO:0090164]; cell adhesion molecule production [GO:0060352]; cell migration [GO:0016477]; cellular response to rapamycin [GO:0072752]; gene expression [GO:0010467]; glycoprotein biosynthetic process [GO:0009101]; Golgi organization [GO:0007030]; Golgi ribbon formation [GO:0090161]; Golgi to plasma membrane protein transport [GO:0043001]; Golgi vesicle budding [GO:0048194]; lamellipodium assembly [GO:0030032]; leukocyte tethering or rolling [GO:0050901]; negative regulation of apoptotic process [GO:0043066]; positive regulation of protein secretion [GO:0050714]; positive regulation of TOR signaling [GO:0032008]; protein retention in Golgi apparatus [GO:0045053]; protein secretion [GO:0009306]; regulation of mitochondrion organization [GO:0010821]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] GO:0000139; GO:0005739; GO:0005758; GO:0005768; GO:0005794; GO:0005802; GO:0005829; GO:0005886; GO:0006890; GO:0007030; GO:0009101; GO:0009306; GO:0010467; GO:0010821; GO:0016477; GO:0019899; GO:0030032; GO:0031985; GO:0032008; GO:0032580; GO:0043001; GO:0043066; GO:0045053; GO:0048194; GO:0050714; GO:0050901; GO:0060352; GO:0070273; GO:0072752; GO:0090161; GO:0090164 4399 XM_029350843.2 1564 1381 955 1289 1279 Q6P2Y2 0 Dynein assembly factor with WDR repeat domains 1 (Outer row dynein assembly protein 16 homolog) (WD repeat-containing protein 69) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005929 4400 XM_029350843.2 1564 1381 955 1289 1279 Q6P2Y2 2.5e-40 Dynein assembly factor with WDR repeat domains 1 (Outer row dynein assembly protein 16 homolog) (WD repeat-containing protein 69) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005929 4401 XM_044311355.1 50 4 11 0 24 P0CT39 2.59e-79 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 4402 XM_044311683.1 0 0 8 0 0 NA NA NA NA NA NA 4403 XM_029340262.2 21 0 27 11 71 E7FAM5 2.53e-105 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 4404 XM_044328658.1 183 119 70 90 142 Q96AY4 8.5e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4405 XM_044328658.1 183 119 70 90 142 Q96AY4 7.87e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4406 XM_044328658.1 183 119 70 90 142 Q96AY4 8.86e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4407 XM_044328658.1 183 119 70 90 142 Q96AY4 1.52e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4408 XM_044328658.1 183 119 70 90 142 Q96AY4 8.14e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4409 XR_006397036.1 77 34 50 37 63 NA NA NA NA NA NA 4410 XR_006393947.1 3 0 6 0 46 NA NA NA NA NA NA 4411 XM_029347781.2 5734 7130 5370 8810 4196 Q93VC9 8.94e-68 Cathepsin B-like protease 2 (EC 3.4.22.-) (Cathepsin B2) (AtCathB2) Arabidopsis thaliana (Mouse-ear cress) defense response [GO:0006952]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of catalytic activity [GO:0050790] GO:0000325; GO:0004197; GO:0005576; GO:0005615; GO:0005764; GO:0006952; GO:0050790; GO:0051603 4412 XM_029329900.2 59 21 0 37 38 P47972 1.19e-23 Neuronal pentraxin-2 (NP2) (Neuronal pentraxin II) (NP-II) Homo sapiens (Human) associative learning [GO:0008306]; chemical synaptic transmission [GO:0007268]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962] GO:0005576; GO:0007268; GO:0008306; GO:0030246; GO:0046872; GO:0098962; GO:0098978 4413 XR_003826847.2 35 64 65 75 47 NA NA NA NA NA NA 4414 XM_044311816.1 89 32 38 91 223 NA NA NA NA NA NA 4415 XM_029336704.2 236 166 186 215 164 NA NA NA NA NA NA 4416 XM_029344359.2 492 280 91 258 437 NA NA NA NA NA NA 4417 XM_029329442.2 1005 1344 1061 1329 411 Q10075 2.6e-62 Glutathione gamma-glutamylcysteinyltransferase (EC 2.3.2.15) (Phytochelatin synthase) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) cellular detoxification of cadmium ion [GO:0098849]; cellular response to cadmium ion [GO:0071276]; detoxification of copper ion [GO:0010273]; phytochelatin biosynthetic process [GO:0046938] GO:0005634; GO:0005737; GO:0005829; GO:0010273; GO:0016756; GO:0046870; GO:0046938; GO:0071276; GO:0098849 4418 XR_006397703.1 16 1 13 11 38 NA NA NA NA NA NA 4419 XM_029327937.2 7 281 23 161 32 NA NA NA NA NA NA 4420 XM_044321390.1 3 10 2 42 3 NA NA NA NA NA NA 4421 XM_029355783.2 94 38 38 30 58 NA NA NA NA NA NA 4422 XM_044326714.1 196 141 88 115 187 NA NA NA NA NA NA 4423 XM_029343909.2 70 0 373 2 91 Q2PZL6 0 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 4424 XM_029343909.2 70 0 373 2 91 Q2PZL6 0 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 4425 XM_029343909.2 70 0 373 2 91 Q2PZL6 0 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 4426 XM_029343909.2 70 0 373 2 91 Q2PZL6 0 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 4427 XM_029343909.2 70 0 373 2 91 Q2PZL6 0 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 4428 XM_029343909.2 70 0 373 2 91 Q2PZL6 0 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 4429 XM_029343909.2 70 0 373 2 91 Q2PZL6 0 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 4430 XM_029343909.2 70 0 373 2 91 Q2PZL6 0 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 4431 XM_029343909.2 70 0 373 2 91 Q2PZL6 0 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 4432 XM_044318856.1 261 169 99 211 132 P31266 0 Recombining binding protein suppressor of hairless (J kappa-recombination signal-binding protein) (RBP-J kappa) Mus musculus (Mouse) angiogenesis [GO:0001525]; aortic valve development [GO:0003176]; arterial endothelial cell fate commitment [GO:0060844]; artery morphogenesis [GO:0048844]; atrioventricular canal development [GO:0036302]; auditory receptor cell fate commitment [GO:0009912]; B cell differentiation [GO:0030183]; blood vessel endothelial cell fate specification [GO:0097101]; blood vessel lumenization [GO:0072554]; blood vessel remodeling [GO:0001974]; cardiac left ventricle morphogenesis [GO:0003214]; cardiac muscle cell myoblast differentiation [GO:0060379]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; cell population proliferation [GO:0008283]; club cell differentiation [GO:0060486]; defense response to bacterium [GO:0042742]; determination of heart left/right asymmetry [GO:0061371]; dorsal aorta morphogenesis [GO:0035912]; endocardium development [GO:0003157]; endocardium morphogenesis [GO:0003160]; epidermal cell fate specification [GO:0009957]; epithelial cell proliferation [GO:0050673]; epithelial to mesenchymal transition [GO:0001837]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; hair follicle maturation [GO:0048820]; heart development [GO:0007507]; heart looping [GO:0001947]; hemopoiesis [GO:0030097]; humoral immune response [GO:0006959]; inflammatory response to antigenic stimulus [GO:0002437]; keratinocyte differentiation [GO:0030216]; labyrinthine layer blood vessel development [GO:0060716]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of ossification [GO:0030279]; negative regulation of stem cell proliferation [GO:2000647]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron differentiation [GO:0030182]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; Notch signaling pathway involved in arterial endothelial cell fate commitment [GO:0060853]; outflow tract morphogenesis [GO:0003151]; pituitary gland development [GO:0021983]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment [GO:1901297]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell proliferation involved in heart morphogenesis [GO:2000138]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of ephrin receptor signaling pathway [GO:1901189]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERBB signaling pathway [GO:1901186]; positive regulation of gene expression [GO:0010628]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription of Notch receptor target [GO:0007221]; pulmonary valve development [GO:0003177]; regulation of cell adhesion involved in heart morphogenesis [GO:0061344]; regulation of epithelial cell proliferation [GO:0050678]; regulation of gene expression [GO:0010468]; regulation of reproductive process [GO:2000241]; regulation of timing of cell differentiation [GO:0048505]; regulation of transcription by RNA polymerase II [GO:0006357]; sebaceous gland development [GO:0048733]; secondary heart field specification [GO:0003139]; somatic stem cell population maintenance [GO:0035019]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222] GO:0000122; GO:0000978; GO:0000981; GO:0001228; GO:0001525; GO:0001756; GO:0001837; GO:0001947; GO:0001974; GO:0002193; GO:0002437; GO:0003139; GO:0003151; GO:0003157; GO:0003160; GO:0003176; GO:0003177; GO:0003198; GO:0003214; GO:0003222; GO:0003677; GO:0003682; GO:0005634; GO:0005654; GO:0005667; GO:0005730; GO:0005737; GO:0006357; GO:0006959; GO:0007219; GO:0007221; GO:0007507; GO:0008283; GO:0009912; GO:0009957; GO:0010468; GO:0010628; GO:0017053; GO:0021983; GO:0030097; GO:0030154; GO:0030182; GO:0030183; GO:0030216; GO:0030279; GO:0030513; GO:0032991; GO:0032993; GO:0035019; GO:0035481; GO:0035912; GO:0036302; GO:0042742; GO:0043011; GO:0043565; GO:0044877; GO:0045165; GO:0045596; GO:0045892; GO:0045893; GO:0045944; GO:0047485; GO:0048505; GO:0048733; GO:0048820; GO:0048844; GO:0050673; GO:0050678; GO:0050679; GO:0060045; GO:0060379; GO:0060412; GO:0060486; GO:0060716; GO:0060844; GO:0060853; GO:0061314; GO:0061344; GO:0061371; GO:0061419; GO:0061629; GO:0072089; GO:0072554; GO:0097101; GO:0120163; GO:0140297; GO:1901186; GO:1901189; GO:1901297; GO:2000138; GO:2000241; GO:2000647 4433 XM_029329783.2 119 73 94 134 238 P20072 4.98e-86 Annexin A7 (Annexin VII) (Annexin-7) (Synexin) Bos taurus (Bovine) NA GO:0005509; GO:0005544; GO:0005634; GO:0005737; GO:0042584 4434 XR_006394550.1 0 0 11 4 3 NA NA NA NA NA NA 4435 XM_029334780.2 528 359 373 443 363 Q8WV07 5.48e-25 Protein LTO1 homolog (Oral cancer-overexpressed protein 1) (Tumor-amplified and overexpressed sequence 1) Homo sapiens (Human) protein maturation by [4Fe-4S] cluster transfer [GO:0106035]; ribosomal large subunit biogenesis [GO:0042273]; telomere maintenance [GO:0000723]; translational initiation [GO:0006413] GO:0000723; GO:0005634; GO:0006413; GO:0042273; GO:0106035 4436 XM_029325331.2 693 477 319 699 927 A7RR04 0 Elongation factor G, mitochondrial (EF-Gmt) (Elongation factor G 1, mitochondrial) (mEF-G 1) (Elongation factor G1) Nematostella vectensis (Starlet sea anemone) mitochondrial translational elongation [GO:0070125] GO:0003746; GO:0003924; GO:0005525; GO:0005739; GO:0070125 4437 XM_029330327.2 26 2 30 7 72 NA NA NA NA NA NA 4438 XR_006393643.1 51 444 732 274 193 NA NA NA NA NA NA 4439 XM_029342330.2 1005 707 411 990 412 P50904 0 Ras GTPase-activating protein 1 (GAP) (GTPase-activating protein) (RasGAP) (Ras p21 protein activator) (p120GAP) Rattus norvegicus (Rat) actin cytoskeleton organization [GO:0030036]; activation of GTPase activity [GO:0090630]; blood vessel morphogenesis [GO:0048514]; cell adhesion [GO:0007155]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; male genitalia development [GO:0030539]; mitotic cytokinesis [GO:0000281]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of glucose import [GO:0046326]; positive regulation of GTPase activity [GO:0043547]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; regulation of actin filament polymerization [GO:0030833]; response to insulin [GO:0032868]; response to xenobiotic stimulus [GO:0009410]; signal transduction [GO:0007165]; vasculogenesis [GO:0001570] GO:0000281; GO:0001570; GO:0001726; GO:0001784; GO:0001934; GO:0001953; GO:0005096; GO:0005102; GO:0005161; GO:0005829; GO:0005886; GO:0007155; GO:0007162; GO:0007165; GO:0009410; GO:0016020; GO:0030036; GO:0030539; GO:0030833; GO:0030971; GO:0031965; GO:0032868; GO:0036120; GO:0043066; GO:0043422; GO:0043524; GO:0043547; GO:0044325; GO:0044344; GO:0044877; GO:0046326; GO:0048146; GO:0048514; GO:0050731; GO:0051020; GO:0071364; GO:0090630; GO:1990782 4440 XM_044329152.1 26 5 3 1 10 NA NA NA NA NA NA 4441 XM_044323353.1 0 0 0 0 209 Q8IWW6 1.28e-82 Rho GTPase-activating protein 12 (Rho-type GTPase-activating protein 12) Homo sapiens (Human) actin filament organization [GO:0007015]; morphogenesis of an epithelial sheet [GO:0002011]; negative regulation of small GTPase mediated signal transduction [GO:0051058]; phagocytosis, engulfment [GO:0006911]; regulation of GTPase activity [GO:0043087]; signal transduction [GO:0007165] GO:0001891; GO:0002011; GO:0005096; GO:0005737; GO:0006911; GO:0007015; GO:0007165; GO:0043087; GO:0051058 4442 XM_044314023.1 70 743 65 280 352 NA NA NA NA NA NA 4443 XM_044320115.1 35 24 85 58 57 Q7RTR2 2.23e-41 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4444 XM_044320115.1 35 24 85 58 57 Q7RTR2 1.15e-35 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4445 XM_044320115.1 35 24 85 58 57 Q7RTR2 2.78e-35 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4446 XM_044320115.1 35 24 85 58 57 Q7RTR2 6.47e-30 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4447 XM_044320115.1 35 24 85 58 57 Q7RTR2 7.88e-26 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4448 XM_044309237.1 4 4 11 2 15 NA NA NA NA NA NA 4449 XM_029334635.2 378 215 14 310 95 Q60HE9 0 Lysosomal alpha-mannosidase (Laman) (EC 3.2.1.24) (Lysosomal acid alpha-mannosidase) (Mannosidase alpha class 2B member 1) (Mannosidase alpha-B) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) mannose metabolic process [GO:0006013] GO:0004559; GO:0005764; GO:0006013; GO:0030246; GO:0046872 4450 XM_029348633.2 18 0 22 3 14 NA NA NA NA NA NA 4451 XR_006394598.1 101 158 59 19 70 NA NA NA NA NA NA 4452 XM_044319957.1 6 3 5 7 0 Q6LAF1 6.16e-50 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 4453 XM_044310629.1 5 15 5 0 0 NA NA NA NA NA NA 4454 XM_029336179.2 317 752 206 26 0 Q61603 1.07e-65 Glycine receptor subunit alpha-4 Mus musculus (Mouse) chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; neuropeptide signaling pathway [GO:0007218]; regulation of membrane potential [GO:0042391]; response to amino acid [GO:0043200]; signal transduction [GO:0007165]; synaptic transmission, glycinergic [GO:0060012] GO:0004888; GO:0005231; GO:0005886; GO:0007165; GO:0007218; GO:0007268; GO:0016594; GO:0016934; GO:0030425; GO:0030594; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0043200; GO:0043204; GO:0045202; GO:0050877; GO:0060012; GO:0098690; GO:0099634; GO:1902476; GO:1904315 4455 XM_044318916.1 0 0 13 0 7 NA NA NA NA NA NA 4456 XM_044327161.1 36 195 11 43 171 Q8R146 0 Acylamino-acid-releasing enzyme (AARE) (EC 3.4.19.1) (Acyl-peptide hydrolase) (APH) (Acylaminoacyl-peptidase) Mus musculus (Mouse) amyloid-beta metabolic process [GO:0050435]; proteolysis [GO:0006508] GO:0004252; GO:0005829; GO:0006508; GO:0008242; GO:0031965; GO:0042802; GO:0050435 4457 XM_029336797.2 174 56 51 102 32 Q5T7V8 8.95e-22 RAB6-interacting golgin (N-terminal kinase-like-binding protein 1) (NTKL-BP1) (NTKL-binding protein 1) (hNTKL-BP1) (SCY1-like 1-binding protein 1) (SCYL1-BP1) (SCYL1-binding protein 1) Homo sapiens (Human) hair follicle morphogenesis [GO:0031069]; non-motile cilium assembly [GO:1905515]; positive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:1901622] GO:0005654; GO:0005730; GO:0005737; GO:0005794; GO:0005829; GO:0031069; GO:1901622; GO:1905515 4458 XM_044326012.1 14 4 5 0 19 NA NA NA NA NA NA 4459 XM_044313663.1 0 0 0 9 4 NA NA NA NA NA NA 4460 XM_029345465.2 148 86 122 158 248 Q8N2E2 2e-39 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 4461 XM_029345465.2 148 86 122 158 248 Q8N2E2 1.2e-37 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 4462 XM_029345465.2 148 86 122 158 248 Q8N2E2 2.11e-36 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 4463 XM_029345465.2 148 86 122 158 248 Q8N2E2 6.56e-35 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 4464 XM_029345465.2 148 86 122 158 248 Q8N2E2 7.6e-32 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 4465 XM_029345465.2 148 86 122 158 248 Q8N2E2 5.4e-25 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 4466 XM_029324154.2 41 0 0 0 0 NA NA NA NA NA NA 4467 XM_029356782.2 97 88 45 54 41 Q02361 1.93e-25 Fork head domain-containing protein FD3 Drosophila melanogaster (Fruit fly) anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0009653; GO:0030154 4468 XM_044309275.1 4 0 3 0 42 NA NA NA NA NA NA 4469 XR_003826056.2 591 336 318 844 1241 NA NA NA NA NA NA 4470 XM_044313038.1 746 849 553 844 990 Q28EX9 8.72e-134 Ubiquitin-like domain-containing CTD phosphatase 1 (EC 3.1.3.16) (Nuclear proteasome inhibitor UBLCP1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005634; GO:0017018 4471 XR_006394128.1 16 2 9 0 13 NA NA NA NA NA NA 4472 XM_044306968.1 70 28 21 39 48 Q96AY4 8.78e-150 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4473 XM_044306968.1 70 28 21 39 48 Q96AY4 1.84e-109 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4474 XM_044306968.1 70 28 21 39 48 Q96AY4 9.87e-89 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4475 XM_044306968.1 70 28 21 39 48 Q96AY4 2.28e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4476 XR_006394692.1 0 0 12 0 5 NA NA NA NA NA NA 4477 XR_006394464.1 189 29 21 101 5 NA NA NA NA NA NA 4478 XM_044320019.1 7 1 0 0 20 NA NA NA NA NA NA 4479 XM_029335944.2 363 133 54 96 0 Q12767 2.14e-137 Transmembrane protein 94 Homo sapiens (Human) NA GO:0016020 4480 XM_029335944.2 363 133 54 96 0 Q12767 2.68e-31 Transmembrane protein 94 Homo sapiens (Human) NA GO:0016020 4481 XM_044328212.1 1 660 405 578 1082 Q8BJ51 4.01e-113 UNC93-like protein MFSD11 (Major facilitator superfamily domain-containing protein 11) (Protein ET) Mus musculus (Mouse) NA GO:0016020 4482 XM_029357774.2 77 40 35 38 74 P18841 1.35e-28 Alpha-1B adrenergic receptor (Alpha-1B adrenoreceptor) (Alpha-1B adrenoceptor) Mesocricetus auratus (Golden hamster) positive regulation of MAPK cascade [GO:0043410]; regulation of cardiac muscle contraction [GO:0055117]; regulation of vasoconstriction [GO:0019229] GO:0004937; GO:0005634; GO:0005737; GO:0005886; GO:0005901; GO:0019229; GO:0031965; GO:0043410; GO:0046982; GO:0055117 4483 XM_029355523.2 49 77 15 31 35 NA NA NA NA NA NA 4484 XM_044310872.1 0 0 0 131 26 NA NA NA NA NA NA 4485 XM_044317875.1 62 51 54 282 324 Q96CG8 2.22e-42 Collagen triple helix repeat-containing protein 1 Homo sapiens (Human) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005576; GO:0005581; GO:0005615; GO:0016477; GO:0016528; GO:0017147; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0062023; GO:0090090; GO:0090103; GO:0090177 4486 XM_044307320.1 18 38 49 145 114 P70627 9.59e-56 Glutamate carboxypeptidase 2 (EC 3.4.17.21) (Folate hydrolase 1) (Folylpoly-gamma-glutamate carboxypeptidase) (FGCP) (Glutamate carboxypeptidase II) (GCPII) (Membrane glutamate carboxypeptidase) (mGCP) (N-acetylated-alpha-linked acidic dipeptidase I) (NAALADase I) (Prostate-specific membrane antigen homolog) (Pteroylpoly-gamma-glutamate carboxypeptidase) Rattus norvegicus (Rat) C-terminal protein deglutamylation [GO:0035609]; folic acid-containing compound metabolic process [GO:0006760]; positive regulation of apoptotic process [GO:0043065]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508] GO:0004180; GO:0004181; GO:0005886; GO:0006508; GO:0006760; GO:0008233; GO:0009986; GO:0016020; GO:0016805; GO:0030163; GO:0035609; GO:0043065; GO:0046872; GO:1904492; GO:1904493 4487 XM_044307320.1 18 38 49 145 114 P70627 9.59e-56 Glutamate carboxypeptidase 2 (EC 3.4.17.21) (Folate hydrolase 1) (Folylpoly-gamma-glutamate carboxypeptidase) (FGCP) (Glutamate carboxypeptidase II) (GCPII) (Membrane glutamate carboxypeptidase) (mGCP) (N-acetylated-alpha-linked acidic dipeptidase I) (NAALADase I) (Prostate-specific membrane antigen homolog) (Pteroylpoly-gamma-glutamate carboxypeptidase) Rattus norvegicus (Rat) C-terminal protein deglutamylation [GO:0035609]; folic acid-containing compound metabolic process [GO:0006760]; positive regulation of apoptotic process [GO:0043065]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508] GO:0004180; GO:0004181; GO:0005886; GO:0006508; GO:0006760; GO:0008233; GO:0009986; GO:0016020; GO:0016805; GO:0030163; GO:0035609; GO:0043065; GO:0046872; GO:1904492; GO:1904493 4488 XM_044308351.1 1570 935 705 1664 1385 O15146 1.04e-60 Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine-protein kinase receptor) (MuSK) (Muscle-specific kinase receptor) Homo sapiens (Human) cell differentiation [GO:0030154]; memory [GO:0007613]; neuromuscular junction development [GO:0007528]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of protein geranylgeranylation [GO:2000541]; positive regulation of protein phosphorylation [GO:0001934]; protein autophosphorylation [GO:0046777]; regulation of synaptic assembly at neuromuscular junction [GO:0008582]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0001934; GO:0004713; GO:0004714; GO:0005518; GO:0005524; GO:0005886; GO:0007169; GO:0007528; GO:0007613; GO:0008582; GO:0010628; GO:0030154; GO:0031594; GO:0033674; GO:0038062; GO:0043235; GO:0045211; GO:0046777; GO:0046872; GO:0071340; GO:2000541 4489 XM_044325127.1 105 191 23 145 137 NA NA NA NA NA NA 4490 XM_029349307.2 353 299 223 422 371 NA NA NA NA NA NA 4491 XM_044318986.1 137 189 18 214 386 P70196 1.5e-80 TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6) Mus musculus (Mouse) activation of NF-kappaB-inducing kinase activity [GO:0007250]; activation of protein kinase activity [GO:0032147]; animal organ morphogenesis [GO:0009887]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; bone remodeling [GO:0046849]; bone resorption [GO:0045453]; cell development [GO:0048468]; cellular response to cytokine stimulus [GO:0071345]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-17-mediated signaling pathway [GO:0097400]; JNK cascade [GO:0007254]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin production [GO:0002637]; response to interleukin-1 [GO:0070555]; signal transduction [GO:0007165]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000122; GO:0000209; GO:0001503; GO:0001701; GO:0001843; GO:0002637; GO:0002726; GO:0004842; GO:0005164; GO:0005634; GO:0005737; GO:0005811; GO:0005829; GO:0005886; GO:0005938; GO:0006955; GO:0006974; GO:0007165; GO:0007249; GO:0007250; GO:0007254; GO:0008270; GO:0009887; GO:0009898; GO:0016567; GO:0019221; GO:0019886; GO:0019901; GO:0030316; GO:0031435; GO:0031624; GO:0031625; GO:0031663; GO:0031666; GO:0031996; GO:0032147; GO:0032735; GO:0032743; GO:0032755; GO:0032813; GO:0032991; GO:0033209; GO:0035631; GO:0042088; GO:0042102; GO:0042475; GO:0042802; GO:0042826; GO:0042981; GO:0043011; GO:0043122; GO:0043123; GO:0043422; GO:0043507; GO:0045453; GO:0045672; GO:0045892; GO:0045944; GO:0046330; GO:0046849; GO:0047485; GO:0048468; GO:0048471; GO:0048661; GO:0050852; GO:0051091; GO:0051092; GO:0051865; GO:0061630; GO:0070498; GO:0070534; GO:0070555; GO:0071222; GO:0071345; GO:0097400; GO:1901224; GO:1904996; GO:2000679 4492 XM_044319686.1 593 408 339 348 470 NA NA NA NA NA NA 4493 XM_044328492.1 0 12 3 1 0 NA NA NA NA NA NA 4494 XM_044316986.1 33 6 3 14 5 Q9Y5X5 3.29e-30 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (G-protein coupled receptor HLWAR77) (Neuropeptide G-protein coupled receptor) Homo sapiens (Human) detection of abiotic stimulus [GO:0009582]; G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0009582; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 4495 XR_003824700.2 331 187 206 177 465 NA NA NA NA NA NA 4496 XM_044311398.1 8 17 37 19 67 P25931 4.94e-24 RYamide receptor (Neuropeptide Y-like receptor) (NPY-R) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218] GO:0001653; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0016020 4497 XM_029333871.2 48 23 19 36 80 NA NA NA NA NA NA 4498 XM_044308767.1 128 168 247 411 80 Q0KIA2 3.61e-52 PP2C-like domain-containing protein CG9801 Drosophila melanogaster (Fruit fly) NA NA 4499 XM_044318517.1 4 10 7 38 0 NA NA NA NA NA NA 4500 XM_044327702.1 74 22 150 46 352 Q9VBW3 8.33e-61 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 4501 XM_044314096.1 34 1 129 1 87 NA NA NA NA NA NA 4502 XM_029357532.2 115 183 72 100 116 NA NA NA NA NA NA 4503 XM_029338400.2 3557 3927 2120 2728 3634 NA NA NA NA NA NA 4504 XM_044310835.1 331 131 51 177 156 Q7RTR2 3.22e-72 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4505 XM_044310835.1 331 131 51 177 156 Q7RTR2 1.31e-71 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4506 XM_044310835.1 331 131 51 177 156 Q7RTR2 4.94e-64 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4507 XM_044310835.1 331 131 51 177 156 Q7RTR2 1.6e-59 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4508 XM_044310835.1 331 131 51 177 156 Q7RTR2 1.98e-58 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4509 XM_044310835.1 331 131 51 177 156 Q7RTR2 2.49e-40 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4510 XM_044310835.1 331 131 51 177 156 Q7RTR2 1.76e-34 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4511 XM_029326042.2 182 83 193 52 1 NA NA NA NA NA NA 4512 XM_029337660.2 0 179 23 0 2 O88871 1.67e-117 Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51) Rattus norvegicus (Rat) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; gamma-aminobutyric acid signaling pathway [GO:0007214]; neuron-glial cell signaling [GO:0150099]; synaptic transmission, GABAergic [GO:0051932] GO:0004888; GO:0004965; GO:0005737; GO:0005886; GO:0007193; GO:0007214; GO:0016020; GO:0030425; GO:0038039; GO:0042734; GO:0043005; GO:0043204; GO:0045211; GO:0046982; GO:0051932; GO:0098978; GO:0098982; GO:0150099; GO:1902710; GO:1902712 4513 XM_044313379.1 149 32 174 94 271 Q6DGA6 1.04e-32 Allantoicase (EC 3.5.3.4) (Allantoate amidinohydrolase) Danio rerio (Zebrafish) (Brachydanio rerio) allantoin catabolic process [GO:0000256]; purine nucleobase metabolic process [GO:0006144] GO:0000256; GO:0004037; GO:0006144 4514 XM_029339745.2 164 133 0 25 0 O88609 1.17e-71 LIM homeobox transcription factor 1-beta (LIM/homeobox protein 1.2) (LMX-1.2) (LIM/homeobox protein LMX1B) Mus musculus (Mouse) camera-type eye development [GO:0043010]; cell population proliferation [GO:0008283]; central nervous system neuron development [GO:0021954]; cerebellum morphogenesis [GO:0021587]; collagen fibril organization [GO:0030199]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral pattern formation [GO:0009953]; embryonic limb morphogenesis [GO:0030326]; limb morphogenesis [GO:0035108]; locomotory behavior [GO:0007626]; memory [GO:0007613]; midbrain development [GO:0030901]; neuron differentiation [GO:0030182]; neuron migration [GO:0001764]; olfactory behavior [GO:0042048]; organ growth [GO:0035265]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of autophagy [GO:0010506]; regulation of DNA-templated transcription [GO:0006355]; regulation of gene expression [GO:0010468]; regulation of intracellular transport [GO:0032386]; regulation of transcription by RNA polymerase II [GO:0006357]; synapse organization [GO:0050808]; trabecular meshwork development [GO:0002930] GO:0000977; GO:0000981; GO:0001228; GO:0001764; GO:0002930; GO:0003700; GO:0005634; GO:0006355; GO:0006357; GO:0007613; GO:0007626; GO:0008283; GO:0009953; GO:0010468; GO:0010506; GO:0021587; GO:0021954; GO:0030182; GO:0030199; GO:0030326; GO:0030901; GO:0032386; GO:0035108; GO:0035265; GO:0042048; GO:0043010; GO:0045944; GO:0046872; GO:0050808; GO:0071542; GO:1990837 4515 XR_006396423.1 0 0 3 0 23 NA NA NA NA NA NA 4516 XR_006394034.1 32 103 56 11 41 NA NA NA NA NA NA 4517 XM_044327445.1 0 6 20 5 215 NA NA NA NA NA NA 4518 XR_006392863.1 13 2 11 3 6 NA NA NA NA NA NA 4519 XM_029332060.2 2487 1901 1908 1681 1489 Q9UH92 9.17e-67 Max-like protein X (Class D basic helix-loop-helix protein 13) (bHLHd13) (Max-like bHLHZip protein) (Protein BigMax) (Transcription factor-like protein 4) Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000785; GO:0000977; GO:0000978; GO:0000981; GO:0001227; GO:0003677; GO:0003700; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006355; GO:0006357; GO:0031965; GO:0042803; GO:0045892; GO:0045944; GO:0046982; GO:0061629; GO:1990837 4520 XM_029330302.2 10049 5173 3801 10703 7706 Q8CFH6 2.55e-157 Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2) Mus musculus (Mouse) cellular response to glucose starvation [GO:0042149]; insulin receptor signaling pathway [GO:0008286]; intracellular signal transduction [GO:0035556]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of insulin receptor signaling pathway [GO:0046626] GO:0000287; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0006468; GO:0008286; GO:0035556; GO:0042149; GO:0046626; GO:0046777; GO:0106310 4521 XM_029330071.2 46 70 37 37 82 P48728 5.1e-147 Aminomethyltransferase, mitochondrial (EC 2.1.2.10) (Glycine cleavage system T protein) (GCVT) Homo sapiens (Human) glycine catabolic process [GO:0006546]; glycine decarboxylation via glycine cleavage system [GO:0019464] GO:0004047; GO:0005654; GO:0005739; GO:0005759; GO:0006546; GO:0008483; GO:0019464 4522 XM_044328370.1 61 6 0 60 0 A6QLE6 1.42e-176 Anoctamin-4 (Transmembrane protein 16D) Bos taurus (Bovine) chloride transmembrane transport [GO:1902476]; lipid transport [GO:0006869]; transmembrane transport [GO:0055085] GO:0005229; GO:0005254; GO:0005886; GO:0006869; GO:0046983; GO:0055085; GO:1902476 4523 XM_029330491.2 987 497 512 977 1023 Q3T8J9 2.58e-33 GON-4-like protein (GON-4 homolog) Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0003712; GO:0005634; GO:0005654; GO:0006355; GO:0016604 4524 XR_006393428.1 16 9 26 25 29 NA NA NA NA NA NA 4525 XM_029343652.2 0 5 3 2 8 NA NA NA NA NA NA 4526 XM_044323459.1 1993 1148 1253 3684 3824 P02466 6.02e-94 Collagen alpha-2(I) chain (Alpha-2 type I collagen) Rattus norvegicus (Rat) blood vessel development [GO:0001568]; bone mineralization [GO:0030282]; cellular response to amino acid stimulus [GO:0071230]; cellular response to organic substance [GO:0071310]; cellular response to retinoic acid [GO:0071300]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; extracellular matrix assembly [GO:0085029]; extracellular matrix organization [GO:0030198]; protein heterotrimerization [GO:0070208]; regulation of blood pressure [GO:0008217]; response to norepinephrine [GO:0071873]; Rho protein signal transduction [GO:0007266]; skeletal system development [GO:0001501]; skin morphogenesis [GO:0043589]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001501; GO:0001568; GO:0002020; GO:0005201; GO:0005576; GO:0005581; GO:0005584; GO:0005615; GO:0007179; GO:0007266; GO:0008217; GO:0030198; GO:0030199; GO:0030282; GO:0030674; GO:0031012; GO:0032963; GO:0042802; GO:0043589; GO:0046332; GO:0046872; GO:0048407; GO:0062023; GO:0070208; GO:0071230; GO:0071300; GO:0071310; GO:0071873; GO:0085029; GO:0097067 4527 XM_044323459.1 1993 1148 1253 3684 3824 P02466 6.6e-36 Collagen alpha-2(I) chain (Alpha-2 type I collagen) Rattus norvegicus (Rat) blood vessel development [GO:0001568]; bone mineralization [GO:0030282]; cellular response to amino acid stimulus [GO:0071230]; cellular response to organic substance [GO:0071310]; cellular response to retinoic acid [GO:0071300]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; extracellular matrix assembly [GO:0085029]; extracellular matrix organization [GO:0030198]; protein heterotrimerization [GO:0070208]; regulation of blood pressure [GO:0008217]; response to norepinephrine [GO:0071873]; Rho protein signal transduction [GO:0007266]; skeletal system development [GO:0001501]; skin morphogenesis [GO:0043589]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001501; GO:0001568; GO:0002020; GO:0005201; GO:0005576; GO:0005581; GO:0005584; GO:0005615; GO:0007179; GO:0007266; GO:0008217; GO:0030198; GO:0030199; GO:0030282; GO:0030674; GO:0031012; GO:0032963; GO:0042802; GO:0043589; GO:0046332; GO:0046872; GO:0048407; GO:0062023; GO:0070208; GO:0071230; GO:0071300; GO:0071310; GO:0071873; GO:0085029; GO:0097067 4528 XM_044323459.1 1993 1148 1253 3684 3824 P02466 5.94e-35 Collagen alpha-2(I) chain (Alpha-2 type I collagen) Rattus norvegicus (Rat) blood vessel development [GO:0001568]; bone mineralization [GO:0030282]; cellular response to amino acid stimulus [GO:0071230]; cellular response to organic substance [GO:0071310]; cellular response to retinoic acid [GO:0071300]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; extracellular matrix assembly [GO:0085029]; extracellular matrix organization [GO:0030198]; protein heterotrimerization [GO:0070208]; regulation of blood pressure [GO:0008217]; response to norepinephrine [GO:0071873]; Rho protein signal transduction [GO:0007266]; skeletal system development [GO:0001501]; skin morphogenesis [GO:0043589]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001501; GO:0001568; GO:0002020; GO:0005201; GO:0005576; GO:0005581; GO:0005584; GO:0005615; GO:0007179; GO:0007266; GO:0008217; GO:0030198; GO:0030199; GO:0030282; GO:0030674; GO:0031012; GO:0032963; GO:0042802; GO:0043589; GO:0046332; GO:0046872; GO:0048407; GO:0062023; GO:0070208; GO:0071230; GO:0071300; GO:0071310; GO:0071873; GO:0085029; GO:0097067 4529 XM_044323459.1 1993 1148 1253 3684 3824 P02466 1.24e-33 Collagen alpha-2(I) chain (Alpha-2 type I collagen) Rattus norvegicus (Rat) blood vessel development [GO:0001568]; bone mineralization [GO:0030282]; cellular response to amino acid stimulus [GO:0071230]; cellular response to organic substance [GO:0071310]; cellular response to retinoic acid [GO:0071300]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; extracellular matrix assembly [GO:0085029]; extracellular matrix organization [GO:0030198]; protein heterotrimerization [GO:0070208]; regulation of blood pressure [GO:0008217]; response to norepinephrine [GO:0071873]; Rho protein signal transduction [GO:0007266]; skeletal system development [GO:0001501]; skin morphogenesis [GO:0043589]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001501; GO:0001568; GO:0002020; GO:0005201; GO:0005576; GO:0005581; GO:0005584; GO:0005615; GO:0007179; GO:0007266; GO:0008217; GO:0030198; GO:0030199; GO:0030282; GO:0030674; GO:0031012; GO:0032963; GO:0042802; GO:0043589; GO:0046332; GO:0046872; GO:0048407; GO:0062023; GO:0070208; GO:0071230; GO:0071300; GO:0071310; GO:0071873; GO:0085029; GO:0097067 4530 XM_044323459.1 1993 1148 1253 3684 3824 P02466 4.81e-32 Collagen alpha-2(I) chain (Alpha-2 type I collagen) Rattus norvegicus (Rat) blood vessel development [GO:0001568]; bone mineralization [GO:0030282]; cellular response to amino acid stimulus [GO:0071230]; cellular response to organic substance [GO:0071310]; cellular response to retinoic acid [GO:0071300]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; extracellular matrix assembly [GO:0085029]; extracellular matrix organization [GO:0030198]; protein heterotrimerization [GO:0070208]; regulation of blood pressure [GO:0008217]; response to norepinephrine [GO:0071873]; Rho protein signal transduction [GO:0007266]; skeletal system development [GO:0001501]; skin morphogenesis [GO:0043589]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001501; GO:0001568; GO:0002020; GO:0005201; GO:0005576; GO:0005581; GO:0005584; GO:0005615; GO:0007179; GO:0007266; GO:0008217; GO:0030198; GO:0030199; GO:0030282; GO:0030674; GO:0031012; GO:0032963; GO:0042802; GO:0043589; GO:0046332; GO:0046872; GO:0048407; GO:0062023; GO:0070208; GO:0071230; GO:0071300; GO:0071310; GO:0071873; GO:0085029; GO:0097067 4531 XM_044323459.1 1993 1148 1253 3684 3824 P02466 1.78e-25 Collagen alpha-2(I) chain (Alpha-2 type I collagen) Rattus norvegicus (Rat) blood vessel development [GO:0001568]; bone mineralization [GO:0030282]; cellular response to amino acid stimulus [GO:0071230]; cellular response to organic substance [GO:0071310]; cellular response to retinoic acid [GO:0071300]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; extracellular matrix assembly [GO:0085029]; extracellular matrix organization [GO:0030198]; protein heterotrimerization [GO:0070208]; regulation of blood pressure [GO:0008217]; response to norepinephrine [GO:0071873]; Rho protein signal transduction [GO:0007266]; skeletal system development [GO:0001501]; skin morphogenesis [GO:0043589]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001501; GO:0001568; GO:0002020; GO:0005201; GO:0005576; GO:0005581; GO:0005584; GO:0005615; GO:0007179; GO:0007266; GO:0008217; GO:0030198; GO:0030199; GO:0030282; GO:0030674; GO:0031012; GO:0032963; GO:0042802; GO:0043589; GO:0046332; GO:0046872; GO:0048407; GO:0062023; GO:0070208; GO:0071230; GO:0071300; GO:0071310; GO:0071873; GO:0085029; GO:0097067 4532 XM_029333939.2 2091 1866 1017 1859 2294 P48601 0 26S proteasome regulatory subunit 4 (P26s4) Drosophila melanogaster (Fruit fly) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] GO:0005524; GO:0005654; GO:0005829; GO:0005838; GO:0008540; GO:0016887; GO:0036402; GO:0043161 4533 XM_029337288.2 377 789 394 936 958 NA NA NA NA NA NA 4534 XM_029353728.2 5 6 3 0 12 NA NA NA NA NA NA 4535 XM_029356769.2 59 28 0 112 0 Q96P65 2.33e-25 Pyroglutamylated RF-amide peptide receptor (AQ27) (G-protein coupled receptor 103) (Orexigenic neuropeptide QRFP receptor) (SP9155) Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:0016020 4536 XM_044324980.1 2 0 10 4 2 Q96AY4 2.04e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4537 XM_044324980.1 2 0 10 4 2 Q96AY4 8.99e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4538 XM_044324980.1 2 0 10 4 2 Q96AY4 3.44e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4539 XM_044324980.1 2 0 10 4 2 Q96AY4 2.7e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4540 XM_044324980.1 2 0 10 4 2 Q96AY4 3.72e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4541 XM_044324980.1 2 0 10 4 2 Q96AY4 3.14e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4542 XM_044324980.1 2 0 10 4 2 Q96AY4 3.75e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4543 XM_044324980.1 2 0 10 4 2 Q96AY4 7.08e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4544 XM_044324980.1 2 0 10 4 2 Q96AY4 3.18e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4545 XM_044324980.1 2 0 10 4 2 Q96AY4 4.5e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4546 XM_029357294.2 1578 1024 830 799 771 Q2KID6 0 Pleiotropic regulator 1 Bos taurus (Bovine) mRNA splicing, via spliceosome [GO:0000398]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; protein localization to nucleus [GO:0034504] GO:0000398; GO:0000974; GO:0001650; GO:0005634; GO:0005662; GO:0016607; GO:0031965; GO:0034504; GO:0071007; GO:0071013; GO:1900087 4547 XM_029352842.2 0 17 90 1 0 Q6EJB6 5.84e-43 U3 small nucleolar RNA-associated protein 14 homolog B (Juvenile spermatogonial depletion protein) Mus musculus (Mouse) cell differentiation [GO:0030154]; meiotic cell cycle [GO:0051321]; rRNA processing [GO:0006364]; spermatogenesis [GO:0007283] GO:0005730; GO:0005829; GO:0006364; GO:0007283; GO:0030154; GO:0032040; GO:0051321 4548 XM_029352842.2 0 17 90 1 0 Q6EJB6 5.41e-37 U3 small nucleolar RNA-associated protein 14 homolog B (Juvenile spermatogonial depletion protein) Mus musculus (Mouse) cell differentiation [GO:0030154]; meiotic cell cycle [GO:0051321]; rRNA processing [GO:0006364]; spermatogenesis [GO:0007283] GO:0005730; GO:0005829; GO:0006364; GO:0007283; GO:0030154; GO:0032040; GO:0051321 4549 XM_029328804.2 664 212 438 353 468 NA NA NA NA NA NA 4550 XM_029331332.2 51 20 0 0 27 Q9YH18 6.67e-61 KH domain-containing RNA-binding protein QKI (Protein quaking) Gallus gallus (Chicken) long-chain fatty acid biosynthetic process [GO:0042759]; mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; myelination [GO:0042552]; positive regulation of gene expression [GO:0010628]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of translation [GO:0006417]; RNA splicing [GO:0008380]; spermatid development [GO:0007286]; vascular associated smooth muscle cell differentiation [GO:0035886]; vasculogenesis [GO:0001570] GO:0001570; GO:0003729; GO:0005634; GO:0005737; GO:0006397; GO:0006417; GO:0007286; GO:0008380; GO:0010628; GO:0017124; GO:0035886; GO:0042552; GO:0042759; GO:0045202; GO:0048024; GO:0051028 4551 XM_029333822.2 112 81 148 242 150 NA NA NA NA NA NA 4552 XM_044315975.1 13 6 6 0 4 NA NA NA NA NA NA 4553 XM_044318868.1 105 84 0 24 0 Q9BSW2 4.02e-55 EF-hand calcium-binding domain-containing protein 4B (Calcium release-activated calcium channel regulator 2A) (CRAC channel regulator 2A) (Calcium release-activated channel regulator 2A) (Ras-related protein Rab-46) Homo sapiens (Human) activation of store-operated calcium channel activity [GO:0032237]; endosomal transport [GO:0016197]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of JNK cascade [GO:0046330]; response to histamine [GO:0034776]; store-operated calcium entry [GO:0002115]; T-helper 1 cell differentiation [GO:0045063] GO:0000139; GO:0001772; GO:0002115; GO:0003924; GO:0005509; GO:0005525; GO:0005576; GO:0005737; GO:0005815; GO:0005886; GO:0016020; GO:0016197; GO:0031982; GO:0032237; GO:0032588; GO:0033093; GO:0034776; GO:0035580; GO:0045063; GO:0046330; GO:0051928 4554 XM_044318868.1 105 84 0 24 0 Q9BSW2 2.59e-35 EF-hand calcium-binding domain-containing protein 4B (Calcium release-activated calcium channel regulator 2A) (CRAC channel regulator 2A) (Calcium release-activated channel regulator 2A) (Ras-related protein Rab-46) Homo sapiens (Human) activation of store-operated calcium channel activity [GO:0032237]; endosomal transport [GO:0016197]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of JNK cascade [GO:0046330]; response to histamine [GO:0034776]; store-operated calcium entry [GO:0002115]; T-helper 1 cell differentiation [GO:0045063] GO:0000139; GO:0001772; GO:0002115; GO:0003924; GO:0005509; GO:0005525; GO:0005576; GO:0005737; GO:0005815; GO:0005886; GO:0016020; GO:0016197; GO:0031982; GO:0032237; GO:0032588; GO:0033093; GO:0034776; GO:0035580; GO:0045063; GO:0046330; GO:0051928 4555 XM_029353604.2 0 0 6 0 0 P25931 1.89e-23 RYamide receptor (Neuropeptide Y-like receptor) (NPY-R) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218] GO:0001653; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0016020 4556 XM_029349132.2 2388 2534 2165 1987 1967 Q9UN37 0 Vacuolar protein sorting-associated protein 4A (EC 3.6.4.6) (Protein SKD2) (VPS4-1) (hVPS4) Homo sapiens (Human) abscission [GO:0009838]; actomyosin contractile ring contraction [GO:0000916]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cell division [GO:0051301]; cytoskeleton-dependent cytokinesis [GO:0061640]; endosomal transport [GO:0016197]; endosomal vesicle fusion [GO:0034058]; ESCRT complex disassembly [GO:1904896]; ESCRT III complex disassembly [GO:1904903]; intracellular cholesterol transport [GO:0032367]; late endosomal microautophagy [GO:0061738]; late endosome to lysosome transport via multivesicular body sorting pathway [GO:0061764]; macroautophagy [GO:0016236]; membrane fission [GO:0090148]; midbody abscission [GO:0061952]; mitotic cytokinesis checkpoint signaling [GO:0044878]; mitotic metaphase plate congression [GO:0007080]; mitotic nuclear membrane reassembly [GO:0007084]; multivesicular body assembly [GO:0036258]; multivesicular body sorting pathway [GO:0071985]; negative regulation of cell death [GO:0060548]; negative regulation of cytokinesis [GO:0032466]; nuclear envelope organization [GO:0006998]; nuclear membrane reassembly [GO:0031468]; nucleus organization [GO:0006997]; plasma membrane repair [GO:0001778]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of viral budding via host ESCRT complex [GO:1903774]; protein targeting to lysosome [GO:0006622]; regulation of protein localization [GO:0032880]; regulation of protein localization to plasma membrane [GO:1903076]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway [GO:0090611]; vacuole organization [GO:0007033]; vesicle budding from membrane [GO:0006900]; vesicle uncoating [GO:0072319]; vesicle-mediated transport [GO:0016192]; viral budding from plasma membrane [GO:0046761]; viral budding via host ESCRT complex [GO:0039702]; viral release from host cell [GO:0019076] GO:0000916; GO:0000922; GO:0001778; GO:0005524; GO:0005634; GO:0005643; GO:0005737; GO:0005764; GO:0005768; GO:0005769; GO:0005770; GO:0005774; GO:0005813; GO:0005829; GO:0005886; GO:0006622; GO:0006900; GO:0006914; GO:0006997; GO:0006998; GO:0007033; GO:0007080; GO:0007084; GO:0008022; GO:0009838; GO:0010008; GO:0016192; GO:0016197; GO:0016236; GO:0016887; GO:0019076; GO:0019904; GO:0030496; GO:0031468; GO:0031902; GO:0032367; GO:0032466; GO:0032880; GO:0034058; GO:0036258; GO:0039702; GO:0043162; GO:0044877; GO:0044878; GO:0046761; GO:0048471; GO:0051301; GO:0060548; GO:0061640; GO:0061738; GO:0061764; GO:0061952; GO:0070062; GO:0071985; GO:0072319; GO:0090148; GO:0090543; GO:0090611; GO:0097352; GO:0140545; GO:1903076; GO:1903543; GO:1903774; GO:1904896; GO:1904903; GO:1904949 4557 XM_029351804.2 958 800 447 719 567 NA NA NA NA NA NA 4558 XR_006397993.1 0 58 90 28 142 NA NA NA NA NA NA 4559 XM_044326173.1 21 109 77 94 155 Q09575 1.15e-48 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 4560 XM_044322481.1 10 2 5 4 18 NA NA NA NA NA NA 4561 XM_029337522.2 719 356 408 701 613 O88480 0 Calcineurin-binding protein cabin-1 (Calcineurin inhibitor) (CAIN) Rattus norvegicus (Rat) chromatin organization [GO:0006325]; negative regulation of cell death [GO:0060548]; nucleosome assembly [GO:0006334]; response to activity [GO:0014823] GO:0004864; GO:0005634; GO:0005737; GO:0006325; GO:0006334; GO:0014823; GO:0019904; GO:0030346; GO:0060548 4562 XM_029337522.2 719 356 408 701 613 O88480 1.75e-39 Calcineurin-binding protein cabin-1 (Calcineurin inhibitor) (CAIN) Rattus norvegicus (Rat) chromatin organization [GO:0006325]; negative regulation of cell death [GO:0060548]; nucleosome assembly [GO:0006334]; response to activity [GO:0014823] GO:0004864; GO:0005634; GO:0005737; GO:0006325; GO:0006334; GO:0014823; GO:0019904; GO:0030346; GO:0060548 4563 XM_044317185.1 565 1964 817 576 1996 NA NA NA NA NA NA 4564 XR_003825746.2 1651 948 2335 1798 589 NA NA NA NA NA NA 4565 XM_044319232.1 0 8 0 0 0 NA NA NA NA NA NA 4566 XM_029344765.2 0 175 359 447 619 P35668 3.55e-119 Glutathione synthetase (GSH synthetase) (GSH-S) (EC 6.3.2.3) (Glutathione synthase) Xenopus laevis (African clawed frog) NA GO:0000287; GO:0004363; GO:0005524; GO:0042803; GO:0043295 4567 XM_029357681.2 0 0 32 0 40 A1L1W9 4.93e-54 Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10) Danio rerio (Zebrafish) (Brachydanio rerio) aromatic amino acid transport [GO:0015801]; thyroid hormone transport [GO:0070327] GO:0005302; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0070327 4568 XM_029334873.2 825 520 533 547 718 Q96HA9 1.17e-45 Peroxisomal membrane protein 11C (Peroxin-11C) (Peroxisomal biogenesis factor 11C) (Protein PEX11 homolog gamma) (PEX11-gamma) Homo sapiens (Human) peroxisome fission [GO:0016559]; regulation of peroxisome size [GO:0044375] GO:0005777; GO:0005778; GO:0016559; GO:0032991; GO:0044375 4569 XM_044316351.1 0 0 0 2 8 NA NA NA NA NA NA 4570 XM_029323506.2 19 8 1 15 11 NA NA NA NA NA NA 4571 XM_029357123.2 2601 1718 795 2020 3781 Q8CFY5 2.51e-91 Protoheme IX farnesyltransferase, mitochondrial (EC 2.5.1.141) (Heme O synthase) Mus musculus (Mouse) aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; heme A biosynthetic process [GO:0006784]; heme biosynthetic process [GO:0006783]; lipid metabolic process [GO:0006629]; mitochondrial fission [GO:0000266]; mitochondrion organization [GO:0007005]; protein farnesylation [GO:0018343]; respiratory chain complex IV assembly [GO:0008535] GO:0000266; GO:0004311; GO:0005730; GO:0005739; GO:0005829; GO:0006629; GO:0006783; GO:0006784; GO:0007005; GO:0008495; GO:0008535; GO:0009060; GO:0017004; GO:0018343; GO:0031966; GO:0070069 4572 XR_003825402.2 2597 1949 1107 2168 1529 NA NA NA NA NA NA 4573 XM_029345952.2 249 270 280 943 132 Q91175 4.54e-38 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (MAR1) Oryzias latipes (Japanese rice fish) (Japanese killifish) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of vasoconstriction [GO:0045907] GO:0001996; GO:0004930; GO:0004937; GO:0005886; GO:0007200; GO:0007204; GO:0007267; GO:0043410; GO:0045907; GO:0071880 4574 XM_044319074.1 9 21 9 6 18 NA NA NA NA NA NA 4575 XR_006392059.1 1 0 47 80 38 NA NA NA NA NA NA 4576 XM_044315433.1 0 0 0 27 0 Q8D3M4 4.97e-79 2-aminoethylphosphonate--pyruvate transaminase (EC 2.6.1.37) (2-aminoethylphosphonate aminotransferase) (AEP transaminase) (AEPT) Vibrio vulnificus (strain CMCP6) organic phosphonate catabolic process [GO:0019700] GO:0019700; GO:0047304 4577 XM_029328783.2 0 292 0 437 84 Q2XWK0 2.93e-152 Synaptic vesicle 2-related protein (SV2-related protein) Xenopus laevis (African clawed frog) NA GO:0022857; GO:0030672 4578 XM_029355607.2 1141 1013 556 1050 1116 Q62825 0 Exocyst complex component 3 (Exocyst complex component Sec6) (rSec6) Rattus norvegicus (Rat) exocyst localization [GO:0051601]; exocytosis [GO:0006887]; protein transport [GO:0015031] GO:0000145; GO:0000149; GO:0005794; GO:0006887; GO:0015031; GO:0016020; GO:0030426; GO:0030496; GO:0042734; GO:0048471; GO:0051601 4579 XM_029349282.2 1300 1227 852 1304 1677 O60341 0 Lysine-specific histone demethylase 1A (EC 1.14.99.66) (BRAF35-HDAC complex protein BHC110) (Flavin-containing amine oxidase domain-containing protein 2) ([histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A) Homo sapiens (Human) alternative mRNA splicing, via spliceosome [GO:0000380]; cellular response to cAMP [GO:0071320]; cellular response to gamma radiation [GO:0071480]; cellular response to UV [GO:0034644]; cerebral cortex development [GO:0021987]; DNA repair-dependent chromatin remodeling [GO:0140861]; guanine metabolic process [GO:0046098]; histone H3-K4 demethylation [GO:0034720]; muscle cell development [GO:0055001]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone H3-K9 methylation [GO:0051573]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of protein binding [GO:0032091]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron maturation [GO:0042551]; positive regulation of cell size [GO:0045793]; positive regulation of chromatin binding [GO:0035563]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein demethylation [GO:0006482]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of DNA methylation-dependent heterochromatin formation [GO:0090308]; regulation of double-strand break repair via homologous recombination [GO:0010569]; regulation of protein localization [GO:0032880]; regulation of transcription by RNA polymerase II [GO:0006357]; response to fungicide [GO:0060992] GO:0000122; GO:0000380; GO:0000781; GO:0000785; GO:0002039; GO:0002052; GO:0003682; GO:0005634; GO:0005654; GO:0005667; GO:0006357; GO:0006482; GO:0010569; GO:0010976; GO:0016491; GO:0019899; GO:0021987; GO:0030374; GO:0031398; GO:0032091; GO:0032451; GO:0032452; GO:0032453; GO:0032454; GO:0032880; GO:0032991; GO:0034644; GO:0034720; GO:0035563; GO:0042551; GO:0043392; GO:0043426; GO:0043433; GO:0043518; GO:0045793; GO:0045892; GO:0045944; GO:0046098; GO:0050660; GO:0050681; GO:0051091; GO:0051572; GO:0051573; GO:0055001; GO:0060765; GO:0060992; GO:0061629; GO:0061752; GO:0071320; GO:0071480; GO:0090308; GO:0120162; GO:0140297; GO:0140682; GO:0140861; GO:1902166; GO:1990391; GO:1990841; GO:2000179; GO:2000648 4580 XM_044311563.1 1 21 0 0 0 NA NA NA NA NA NA 4581 XM_044326373.1 674 921 589 650 811 Q8K339 4.16e-134 DNA/RNA-binding protein KIN17 (Binding to curved DNA) (KIN, antigenic determinant of recA protein) Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; mRNA processing [GO:0006397] GO:0003690; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006260; GO:0006281; GO:0006310; GO:0006397; GO:0006974; GO:0016363; GO:0032991; GO:0043231; GO:0046872 4582 XM_044327090.1 0 0 5 2 8 NA NA NA NA NA NA 4583 XR_003826880.2 0 0 0 3 9 NA NA NA NA NA NA 4584 XM_029349768.2 132 0 17 0 0 NA NA NA NA NA NA 4585 XM_044323442.1 446 780 362 800 389 Q9EQD2 1.65e-26 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 4586 XM_044307227.1 5 0 10 0 11 NA NA NA NA NA NA 4587 XM_029340978.2 568 257 219 686 125 Q8K078 5.93e-119 Solute carrier organic anion transporter family member 4A1 (Organic anion-transporting polypeptide E) (OATP-E) (Sodium-independent organic anion transporter E) (Solute carrier family 21 member 12) Mus musculus (Mouse) sodium-independent organic anion transport [GO:0043252]; thyroid hormone metabolic process [GO:0042403] GO:0005886; GO:0008514; GO:0015132; GO:0015347; GO:0015349; GO:0042403; GO:0043252 4588 XM_044329072.1 627 491 338 703 596 NA NA NA NA NA NA 4589 XM_044319579.1 1112 278 289 132 1511 Q6INN8 2.54e-156 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (dNTPase) (EC 3.1.5.-) Xenopus laevis (African clawed frog) cellular response to DNA damage stimulus [GO:0006974]; dATP catabolic process [GO:0046061]; defense response to virus [GO:0051607]; deoxyribonucleotide catabolic process [GO:0009264]; dGTP catabolic process [GO:0006203]; DNA strand resection involved in replication fork processing [GO:0110025]; double-strand break repair via homologous recombination [GO:0000724]; innate immune response [GO:0045087]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; protein homotetramerization [GO:0051289]; regulation of innate immune response [GO:0045088]; somatic hypermutation of immunoglobulin genes [GO:0016446] GO:0000724; GO:0003676; GO:0003697; GO:0003723; GO:0005525; GO:0005634; GO:0006203; GO:0006974; GO:0008270; GO:0008832; GO:0009264; GO:0016446; GO:0016793; GO:0032567; GO:0035861; GO:0045087; GO:0045088; GO:0046061; GO:0051289; GO:0051607; GO:0060339; GO:0106375; GO:0110025 4590 XM_029340804.2 16507 11170 9367 16434 15344 B0S5G3 4.58e-83 NA NA NA NA 4591 XM_044329236.1 1078 643 605 937 995 NA NA NA NA NA NA 4592 XM_029355951.2 3 30 50 9 53 NA NA NA NA NA NA 4593 XM_029349275.2 993 580 644 1220 586 NA NA NA NA NA NA 4594 XR_006395544.1 482 100 148 356 503 C0H691 2.83e-46 Small cysteine-rich protein 2 (Amil-SCRiP2) (SCRiP2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0042151; GO:0090729 4595 XM_044319784.1 842 456 611 6 459 Q9P2E3 0 NFX1-type zinc finger-containing protein 1 Homo sapiens (Human) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 4596 XM_044319784.1 842 456 611 6 459 Q9P2E3 2.05e-67 NFX1-type zinc finger-containing protein 1 Homo sapiens (Human) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 4597 XM_029340502.2 436 218 152 212 165 Q5XIN7 1.03e-172 Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGnT1) (EC 2.4.1.-) Rattus norvegicus (Rat) O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493] GO:0000139; GO:0006493; GO:0008375; GO:0016020; GO:0016266; GO:0030145; GO:0047223 4598 XM_029326826.2 1955 2177 1267 2422 2214 NA NA NA NA NA NA 4599 XM_044322948.1 0 0 0 18 0 NA NA NA NA NA NA 4600 XM_044308468.1 529 122 26 198 43 Q4R3J0 1.52e-64 RNA 3'-terminal phosphate cyclase (RNA cyclase) (RNA-3'-phosphate cyclase) (EC 6.5.1.4) (RNA terminal phosphate cyclase domain-containing protein 1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) RNA processing [GO:0006396] GO:0003963; GO:0005524; GO:0005654; GO:0006396 4601 XM_044312008.1 57 143 199 59 498 NA NA NA NA NA NA 4602 XR_003825828.2 0 16 21 8 107 A1L1W9 8.54e-22 Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10) Danio rerio (Zebrafish) (Brachydanio rerio) aromatic amino acid transport [GO:0015801]; thyroid hormone transport [GO:0070327] GO:0005302; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0070327 4603 XR_003825828.2 0 16 21 8 107 A1L1W9 8.54e-22 Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10) Danio rerio (Zebrafish) (Brachydanio rerio) aromatic amino acid transport [GO:0015801]; thyroid hormone transport [GO:0070327] GO:0005302; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0070327 4604 XR_003825828.2 0 16 21 8 107 A1L1W9 8.54e-22 Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10) Danio rerio (Zebrafish) (Brachydanio rerio) aromatic amino acid transport [GO:0015801]; thyroid hormone transport [GO:0070327] GO:0005302; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0070327 4605 XM_029330063.2 348 639 208 383 338 Q8R431 1.54e-82 Monoglyceride lipase (MGL) (EC 3.1.1.23) (Monoacylglycerol lipase) (MAGL) Rattus norvegicus (Rat) acylglycerol catabolic process [GO:0046464]; arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; long-term synaptic depression [GO:0060292]; monoacylglycerol catabolic process [GO:0052651]; positive regulation of vasoconstriction [GO:0045907]; regulation of axon extension [GO:0030516]; regulation of endocannabinoid signaling pathway [GO:2000124]; regulation of inflammatory response [GO:0050727]; regulation of sensory perception of pain [GO:0051930]; regulation of signal transduction [GO:0009966]; triglyceride catabolic process [GO:0019433] GO:0005811; GO:0005829; GO:0006633; GO:0009966; GO:0016020; GO:0016298; GO:0016787; GO:0019369; GO:0019433; GO:0019898; GO:0030424; GO:0030516; GO:0042803; GO:0043196; GO:0045202; GO:0045907; GO:0046464; GO:0047372; GO:0050727; GO:0051930; GO:0052651; GO:0060292; GO:2000124 4606 XR_006397988.1 0 2372 426 330 918 NA NA NA NA NA NA 4607 XM_029356380.2 0 56 41 17 19 P04274 6.67e-26 Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor) Mesocricetus auratus (Golden hamster) activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; bone resorption [GO:0045453]; brown fat cell differentiation [GO:0050873]; cellular response to amyloid-beta [GO:1904646]; desensitization of G protein-coupled receptor signaling pathway by arrestin [GO:0002032]; diet induced thermogenesis [GO:0002024]; heat generation [GO:0031649]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of smooth muscle contraction [GO:0045986]; norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0002025]; positive regulation of AMPA receptor activity [GO:2000969]; positive regulation of autophagosome maturation [GO:1901098]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of lipophagy [GO:1904504]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mini excitatory postsynaptic potential [GO:0061885]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor-mediated endocytosis [GO:0006898]; regulation of sodium ion transport [GO:0002028]; response to cold [GO:0009409]; smooth muscle contraction [GO:0006939]; transcription by RNA polymerase II [GO:0006366] GO:0001540; GO:0002024; GO:0002025; GO:0002028; GO:0002032; GO:0004941; GO:0005634; GO:0005769; GO:0005794; GO:0006366; GO:0006898; GO:0006939; GO:0007189; GO:0007190; GO:0008179; GO:0009409; GO:0010739; GO:0015459; GO:0016324; GO:0030501; GO:0031649; GO:0040015; GO:0042803; GO:0043235; GO:0043410; GO:0044877; GO:0045453; GO:0045944; GO:0045986; GO:0050873; GO:0051380; GO:0061885; GO:0071902; GO:0098992; GO:0120162; GO:1901098; GO:1904504; GO:1904646; GO:2000969 4608 XM_029324721.2 0 0 0 4 18 NA NA NA NA NA NA 4609 XM_044318785.1 3 31 1 3 0 P0CM16 2.23e-59 ADP-ribosylation factor Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans) intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192] GO:0003924; GO:0005525; GO:0005737; GO:0005794; GO:0005886; GO:0006886; GO:0016192 4610 XM_029346402.2 0 25 138 6 0 Q8BYM7 2.95e-143 Radial spoke head protein 4 homolog A (Radial spoke head-like protein 3) Mus musculus (Mouse) axoneme assembly [GO:0035082]; cilium movement [GO:0003341]; cilium movement involved in cell motility [GO:0060294]; maintenance of ciliary planar beating movement pattern [GO:0120221]; radial spoke assembly [GO:0062177] GO:0001534; GO:0001535; GO:0003341; GO:0005654; GO:0005730; GO:0005929; GO:0005930; GO:0035082; GO:0060294; GO:0062177; GO:0120221 4611 XM_044318403.1 0 4 0 8 69 P0CT39 8.71e-70 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 4612 XR_006395434.1 66 31 71 56 59 Q0EEE2 1.61e-53 Patched domain-containing protein 3 (RND-type protein RNDEu-3) Mus musculus (Mouse) NA GO:0005783; GO:0005789; GO:0005886; GO:0016020; GO:0097225 4613 XM_044322986.1 99 10 38 55 57 Q7RTR2 1.17e-73 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4614 XM_044322986.1 99 10 38 55 57 Q7RTR2 6.29e-73 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4615 XM_044322986.1 99 10 38 55 57 Q7RTR2 7.96e-69 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4616 XM_044322986.1 99 10 38 55 57 Q7RTR2 8.78e-69 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4617 XM_044322986.1 99 10 38 55 57 Q7RTR2 2.42e-60 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4618 XM_044322986.1 99 10 38 55 57 Q7RTR2 9.87e-59 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4619 XM_044322986.1 99 10 38 55 57 Q7RTR2 2.11e-49 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4620 XM_044322986.1 99 10 38 55 57 Q7RTR2 2.2e-34 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4621 XR_006394984.1 0 13 0 0 0 NA NA NA NA NA NA 4622 XM_029323541.2 1871 3845 822 2037 2178 Q0MQC1 8.96e-22 Acyl carrier protein, mitochondrial (ACP) (NADH-ubiquinone oxidoreductase 9.6 kDa subunit) Pongo pygmaeus (Bornean orangutan) [2Fe-2S] cluster assembly [GO:0044571]; fatty acid biosynthetic process [GO:0006633]; mitochondrial respiratory chain complex I assembly [GO:0032981] GO:0005747; GO:0006633; GO:0032981; GO:0044571 4623 XM_029350725.2 8 26 0 0 105 NA NA NA NA NA NA 4624 XM_044311565.1 605 340 297 497 784 Q6P5E4 0 UDP-glucose:glycoprotein glucosyltransferase 1 (UGT1) (EC 2.4.1.-) (UDP--Glc:glycoprotein glucosyltransferase) (UDP-glucose ceramide glucosyltransferase-like 1) Mus musculus (Mouse) ER-associated misfolded protein catabolic process [GO:0071712]; protein N-linked glycosylation via asparagine [GO:0018279] GO:0003980; GO:0005783; GO:0005788; GO:0005793; GO:0018279; GO:0032991; GO:0051082; GO:0071712 4625 XR_006393289.1 0 70 23 9 96 NA NA NA NA NA NA 4626 XM_029328727.2 0 0 0 0 14 NA NA NA NA NA NA 4627 XM_029355361.2 13746 11945 7771 15127 14175 NA NA NA NA NA NA 4628 XM_029347278.2 118 46 77 115 147 Q05973 0 Sodium channel protein 1 brain (Sodium channel protein I brain) Heterololigo bleekeri (Spear squid) (Loligo bleekeri) regulation of ion transmembrane transport [GO:0034765] GO:0001518; GO:0005244; GO:0005248; GO:0034765 4629 XM_029342761.2 42 7 51 2 139 NA NA NA NA NA NA 4630 XM_044308709.1 42 27 3 0 8 NA NA NA NA NA NA 4631 XM_044319263.1 213 3 1 137 10 Q8BHB0 5.98e-31 Nucleotide-binding oligomerization domain-containing protein 1 (Caspase recruitment domain-containing protein 4) Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cellular response to muramyl dipeptide [GO:0071225]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; ERK1 and ERK2 cascade [GO:0070371]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of cell death [GO:0010942]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of xenophagy [GO:1904417]; regulation of apoptotic process [GO:0042981]; stress-activated MAPK cascade [GO:0051403]; xenophagy [GO:0098792] GO:0002221; GO:0002606; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006915; GO:0006919; GO:0007249; GO:0007254; GO:0010942; GO:0016045; GO:0016323; GO:0016324; GO:0032731; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0035556; GO:0038187; GO:0042742; GO:0042802; GO:0042803; GO:0042981; GO:0043123; GO:0043280; GO:0044877; GO:0045087; GO:0045335; GO:0046330; GO:0050700; GO:0050830; GO:0051000; GO:0051092; GO:0051403; GO:0060907; GO:0070371; GO:0070374; GO:0071225; GO:0098792; GO:1901224; GO:1904417 4632 XM_029352639.2 349 0 91 774 145 NA NA NA NA NA NA 4633 XM_044325748.1 0 11 11 7 1 Q6DIV6 6.31e-49 Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Solute carrier family 32 member 1) (Vesicular GABA transporter) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) beta-alanine transport [GO:0001762]; gamma-aminobutyric acid import [GO:0051939]; gamma-aminobutyric acid transport [GO:0015812]; glycine transport [GO:0015816]; neurotransmitter transport [GO:0006836] GO:0001762; GO:0006836; GO:0008021; GO:0015185; GO:0015187; GO:0015812; GO:0015816; GO:0030659; GO:0042995; GO:0051939; GO:0098793; GO:0140799; GO:0140800 4634 XM_029349968.2 880 900 793 1269 1232 Q5SRE5 0 Nucleoporin NUP188 (hNup188) Homo sapiens (Human) mRNA transport [GO:0051028]; nucleocytoplasmic transport [GO:0006913]; protein import into nucleus [GO:0006606]; RNA export from nucleus [GO:0006405] GO:0005635; GO:0005643; GO:0005829; GO:0006405; GO:0006606; GO:0006913; GO:0016020; GO:0017056; GO:0044611; GO:0051028 4635 XM_044329130.1 315 451 233 420 248 B5X4E0 1.33e-23 Calumenin-B Salmo salar (Atlantic salmon) NA GO:0005509; GO:0005576; GO:0005789; GO:0005794; GO:0033018; GO:0042470 4636 XM_044323719.1 6 8 23 17 82 NA NA NA NA NA NA 4637 XM_029329030.2 0 21 0 0 310 Q5T447 0 E3 ubiquitin-protein ligase HECTD3 (EC 2.3.2.26) (HECT domain-containing protein 3) (HECT-type E3 ubiquitin transferase HECTD3) Homo sapiens (Human) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] GO:0004842; GO:0019905; GO:0043161; GO:0048471 4638 XM_044308750.1 0 9 4 0 0 Q8JGS1 3.83e-72 SCL-interrupting locus protein homolog Danio rerio (Zebrafish) (Brachydanio rerio) body morphogenesis [GO:0010171]; centrosome duplication [GO:0051298]; mitotic spindle organization [GO:0007052]; neuron cellular homeostasis [GO:0070050]; positive regulation of centriole replication [GO:0046601]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of mitotic spindle organization [GO:0110028]; positive regulation of spindle assembly [GO:1905832]; protein localization to centrosome [GO:0071539]; regulation of centriole replication [GO:0046599]; smoothened signaling pathway [GO:0007224]; spindle assembly [GO:0051225] GO:0005737; GO:0005813; GO:0005814; GO:0007052; GO:0007224; GO:0010171; GO:0046599; GO:0046601; GO:0051225; GO:0051298; GO:0070050; GO:0071539; GO:0110028; GO:0120099; GO:1900087; GO:1905832 4639 XM_044308846.1 20 3 2 10 35 O16025 1.4e-46 Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (AOS) (EC 4.2.1.-) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)] Plexaura homomalla (Black sea rod) arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; lipid oxidation [GO:0034440]; oxylipin biosynthetic process [GO:0031408] GO:0005506; GO:0005737; GO:0006633; GO:0009978; GO:0016020; GO:0019369; GO:0020037; GO:0031408; GO:0034440; GO:0047677 4640 XM_044309290.1 39 24 3 2 33 NA NA NA NA NA NA 4641 XM_044320957.1 107 132 97 256 68 NA NA NA NA NA NA 4642 XM_044328769.1 33 0 0 0 0 NA NA NA NA NA NA 4643 XM_044327431.1 58 34 0 33 0 O70165 8.52e-68 Ficolin-1 (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin-alpha) (M-ficolin) Mus musculus (Mouse) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation, lectin pathway [GO:0001867]; G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of interleukin-8 production [GO:0032757] GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005581; GO:0005615; GO:0007186; GO:0030246; GO:0031232; GO:0032757; GO:0038187; GO:0046872; GO:0062023; GO:0097367 4644 XR_006396497.1 48 26 49 50 42 NA NA NA NA NA NA 4645 XM_029333651.2 5889 3499 2846 13741 10995 P42566 1.14e-25 Epidermal growth factor receptor substrate 15 (Protein Eps15) (Protein AF-1p) Homo sapiens (Human) clathrin coat assembly [GO:0048268]; endocytic recycling [GO:0032456]; endocytosis [GO:0006897]; endosomal transport [GO:0016197]; Golgi to endosome transport [GO:0006895]; protein transport [GO:0015031]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; vesicle organization [GO:0016050]; viral entry into host cell [GO:0046718] GO:0005509; GO:0005829; GO:0005886; GO:0005905; GO:0006895; GO:0006897; GO:0015031; GO:0016020; GO:0016050; GO:0016197; GO:0016235; GO:0017124; GO:0019065; GO:0030132; GO:0031593; GO:0031901; GO:0032456; GO:0043231; GO:0045296; GO:0046718; GO:0048268 4646 XM_029349332.2 19 0 7 17 24 Q6DFC2 9.33e-142 Coiled-coil domain-containing protein 77 Xenopus laevis (African clawed frog) NA NA 4647 XM_044316619.1 40 109 42 69 5 NA NA NA NA NA NA 4648 XR_006395083.1 87 22 108 218 222 NA NA NA NA NA NA 4649 XR_006391726.1 108 9 7 1 3 NA NA NA NA NA NA 4650 XR_003823492.2 2376 2508 1558 1763 1073 NA NA NA NA NA NA 4651 XM_044314405.1 15 0 9 0 0 P70195 2.12e-42 Proteasome subunit beta type-7 (EC 3.4.25.1) (Macropain chain Z) (Multicatalytic endopeptidase complex chain Z) (Proteasome subunit Z) Mus musculus (Mouse) proteasomal protein catabolic process [GO:0010498] GO:0000502; GO:0004175; GO:0004298; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005839; GO:0010498; GO:0016604; GO:0019774 4652 XM_044314405.1 15 0 9 0 0 P70195 2.12e-42 Proteasome subunit beta type-7 (EC 3.4.25.1) (Macropain chain Z) (Multicatalytic endopeptidase complex chain Z) (Proteasome subunit Z) Mus musculus (Mouse) proteasomal protein catabolic process [GO:0010498] GO:0000502; GO:0004175; GO:0004298; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005839; GO:0010498; GO:0016604; GO:0019774 4653 XM_044314405.1 15 0 9 0 0 P70195 2.12e-42 Proteasome subunit beta type-7 (EC 3.4.25.1) (Macropain chain Z) (Multicatalytic endopeptidase complex chain Z) (Proteasome subunit Z) Mus musculus (Mouse) proteasomal protein catabolic process [GO:0010498] GO:0000502; GO:0004175; GO:0004298; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005839; GO:0010498; GO:0016604; GO:0019774 4654 XM_044314405.1 15 0 9 0 0 P70195 2.12e-42 Proteasome subunit beta type-7 (EC 3.4.25.1) (Macropain chain Z) (Multicatalytic endopeptidase complex chain Z) (Proteasome subunit Z) Mus musculus (Mouse) proteasomal protein catabolic process [GO:0010498] GO:0000502; GO:0004175; GO:0004298; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005839; GO:0010498; GO:0016604; GO:0019774 4655 XM_029327632.2 462 382 234 307 0 NA NA NA NA NA NA 4656 XM_029335703.2 1683 966 994 1526 1359 Q6NUB7 0 Ubiquitin thioesterase zranb1-B (EC 3.4.19.12) (Zinc finger Ran-binding domain-containing protein 1B) Xenopus laevis (African clawed frog) cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; positive regulation of Wnt signaling pathway [GO:0030177]; protein K29-linked deubiquitination [GO:0035523]; protein K33-linked deubiquitination [GO:1990168]; protein K63-linked deubiquitination [GO:0070536]; regulation of cell morphogenesis [GO:0022604]; Wnt signaling pathway [GO:0016055] GO:0004843; GO:0005634; GO:0005737; GO:0007010; GO:0016055; GO:0016477; GO:0022604; GO:0030177; GO:0035523; GO:0046872; GO:0070536; GO:1990168 4657 XM_044326462.1 12 27 10 27 51 NA NA NA NA NA NA 4658 XR_006396360.1 46 9 19 0 0 NA NA NA NA NA NA 4659 XM_029339278.2 0 33 0 0 0 NA NA NA NA NA NA 4660 XM_029331259.2 211 183 119 89 180 P42322 9.16e-26 Calcineurin subunit B (Calcineurin regulatory subunit) (Protein phosphatase 2B regulatory subunit) Naegleria gruberi (Amoeba) NA GO:0005509; GO:0008597 4661 XM_029324757.2 18 4 6 3 53 P25931 1.1e-29 RYamide receptor (Neuropeptide Y-like receptor) (NPY-R) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218] GO:0001653; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0016020 4662 XR_006396969.1 30 23 34 2 144 NA NA NA NA NA NA 4663 XM_029350895.2 3430 3876 2005 4035 4174 Q9Z255 1.57e-98 Ubiquitin-conjugating enzyme E2 A (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme A) (RAD6 homolog A) (HR6A) (mHR6A) (Ubiquitin carrier protein A) (Ubiquitin-protein ligase A) Mus musculus (Mouse) blastocyst hatching [GO:0001835]; DNA repair [GO:0006281]; histone H2A ubiquitination [GO:0033522]; histone ubiquitination [GO:0016574]; in utero embryonic development [GO:0001701]; maternal process involved in female pregnancy [GO:0060135]; positive regulation of cell population proliferation [GO:0008284]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K11-linked ubiquitination [GO:0070979]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; response to UV [GO:0009411] GO:0000209; GO:0000785; GO:0001701; GO:0001741; GO:0001835; GO:0004842; GO:0005524; GO:0006281; GO:0008284; GO:0009411; GO:0016567; GO:0016574; GO:0031625; GO:0033503; GO:0033522; GO:0043161; GO:0051865; GO:0060135; GO:0061631; GO:0070936; GO:0070979 4664 XM_029356306.2 233 181 225 166 168 NA NA NA NA NA NA 4665 XM_044309750.1 0 7 2 0 3 NA NA NA NA NA NA 4666 XM_044312133.1 0 0 13 18 108 NA NA NA NA NA NA 4667 XM_029334861.2 2127 3014 1645 2080 1763 Q7ZUG0 6.1e-49 Small nuclear ribonucleoprotein E (snRNP-E) (Sm protein E) (Sm-E) (SmE) Danio rerio (Zebrafish) (Brachydanio rerio) mRNA splicing, via spliceosome [GO:0000398]; spliceosomal snRNP assembly [GO:0000387] GO:0000387; GO:0000398; GO:0003723; GO:0005634; GO:0005682; GO:0005685; GO:0005686; GO:0005687; GO:0005829; GO:0034709; GO:0034715; GO:0034719; GO:0046540; GO:0071005; GO:0071007; GO:0071011 4668 XR_003823945.2 0 0 0 33 94 NA NA NA NA NA NA 4669 XR_006391342.1 0 0 2 6 6 NA NA NA NA NA NA 4670 XM_029339178.2 1852 1383 1904 2524 2224 NA NA NA NA NA NA 4671 XM_044308432.1 4 3 1 1 12 P35061 1.53e-59 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 4672 XM_029340321.2 124 108 43 100 87 NA NA NA NA NA NA 4673 XM_044316791.1 528 315 34 153 11 NA NA NA NA NA NA 4674 XM_044315697.1 72 17 32 23 30 Q09575 5.08e-27 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 4675 XM_029340469.2 0 0 1 271 98 O13067 9.3e-122 Condensin complex subunit 2 (Barren homolog) (Chromosome assembly protein xCAP-H) (Chromosome-associated protein H) (Non-SMC condensin I complex subunit H) Xenopus laevis (African clawed frog) cell division [GO:0051301]; mitotic chromosome condensation [GO:0007076] GO:0000796; GO:0005634; GO:0005829; GO:0007076; GO:0051301 4676 XR_006392380.1 258 0 0 225 0 P31836 6.42e-38 Neural cell adhesion molecule 1 (N-CAM-1) (NCAM-1) Bos taurus (Bovine) axon guidance [GO:0007411]; dendrite self-avoidance [GO:0070593]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005886; GO:0007156; GO:0007411; GO:0030424; GO:0070593; GO:0098632 4677 XM_029345956.2 0 0 36 0 0 Q9GLP1 9.4e-26 Coagulation factor V (Activated protein C cofactor) [Cleaved into: Coagulation factor V heavy chain; Coagulation factor V light chain] Sus scrofa (Pig) blood circulation [GO:0008015]; blood coagulation [GO:0007596] GO:0005507; GO:0005576; GO:0007596; GO:0008015; GO:0031091 4678 XM_044325250.1 0 28 0 22 36 NA NA NA NA NA NA 4679 XM_044309646.1 97 76 34 38 24 Q9Z2W0 0 Aspartyl aminopeptidase (EC 3.4.11.21) Mus musculus (Mouse) proteolysis [GO:0006508] GO:0004177; GO:0005829; GO:0006508; GO:0008237; GO:0008270; GO:0042802 4680 XR_006393030.1 82 1 3 77 16 NA NA NA NA NA NA 4681 XM_029338981.2 52 16 19 47 25 NA NA NA NA NA NA 4682 XM_029348422.2 176 120 122 347 268 NA NA NA NA NA NA 4683 XM_029339966.2 3883 2076 961 1710 6062 P84239 2.98e-89 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 4684 XM_029335187.2 916 661 373 681 803 Q9CWX9 0 Probable ATP-dependent RNA helicase DDX47 (EC 3.6.4.13) (DEAD box protein 47) Mus musculus (Mouse) extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; mRNA processing [GO:0006397]; RNA splicing [GO:0008380]; rRNA processing [GO:0006364] GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005730; GO:0006364; GO:0006397; GO:0008380; GO:0008625; GO:0016887 4685 XM_029347123.2 35 16 15 24 100 NA NA NA NA NA NA 4686 XM_044329231.1 17 3 9 1 112 NA NA NA NA NA NA 4687 XM_029338903.2 2 0 0 5 12 NA NA NA NA NA NA 4688 XM_044315859.1 14 0 2 0 6 NA NA NA NA NA NA 4689 XM_029328131.2 14 17 50 28 61 NA NA NA NA NA NA 4690 XM_029329944.2 0 19 0 0 29 P17971 1.57e-88 Potassium voltage-gated channel protein Shal (Shaker cognate l) (Shal2) Drosophila melanogaster (Fruit fly) associative learning [GO:0008306]; chemical synaptic transmission [GO:0007268]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005250; GO:0005886; GO:0006813; GO:0007268; GO:0008076; GO:0008306; GO:0016020; GO:0030425; GO:0034765; GO:0043204; GO:0045202; GO:0051260; GO:0071805 4691 XR_006396717.1 68 90 42 9 132 NA NA NA NA NA NA 4692 XM_029344464.2 4137 4636 2848 3654 3395 Q7ZW47 2.84e-55 Double-stranded RNA-binding protein Staufen homolog 2 Danio rerio (Zebrafish) (Brachydanio rerio) anterograde dendritic transport of messenger ribonucleoprotein complex [GO:0098964]; germ cell development [GO:0007281]; germ cell migration [GO:0008354]; intracellular mRNA localization [GO:0008298]; protein localization to synapse [GO:0035418] GO:0003725; GO:0003729; GO:0005874; GO:0005886; GO:0007281; GO:0008298; GO:0008354; GO:0010494; GO:0032839; GO:0035418; GO:0043005; GO:0043025; GO:0098964; GO:1990124 4693 XM_029353549.2 185 78 103 174 139 B8VIU6 4.69e-38 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 4694 XM_044322404.1 20 60 11 14 49 NA NA NA NA NA NA 4695 XM_044307601.1 0 12 11 85 7 Q5PRF9 5.51e-76 Protein Smaug homolog 2 (Smaug 2) (hSmaug2) (Sterile alpha motif domain-containing protein 4B) (SAM domain-containing protein 4B) Homo sapiens (Human) nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289] GO:0000289; GO:0000932; GO:0003723; GO:0003729; GO:0005634; GO:0005829; GO:0030371 4696 XR_006393557.1 57 89 35 111 70 NA NA NA NA NA NA 4697 XM_029335487.2 552 1124 2054 2596 1484 NA NA NA NA NA NA 4698 XM_044325319.1 16 17 8 11 0 Q2KIA4 1.26e-110 Stearoyl-CoA desaturase 5 (EC 1.14.19.1) (Acyl-CoA-desaturase 4) (Stearoyl-CoA 9-desaturase) Bos taurus (Bovine) monounsaturated fatty acid biosynthetic process [GO:1903966]; unsaturated fatty acid biosynthetic process [GO:0006636] GO:0004768; GO:0005506; GO:0005789; GO:0006636; GO:0016491; GO:1903966 4699 XM_029328011.2 58 106 10 106 18 Q8WUA2 1.52e-158 Peptidyl-prolyl cis-trans isomerase-like 4 (PPIase) (EC 5.2.1.8) (Cyclophilin-like protein PPIL4) (Rotamase PPIL4) Homo sapiens (Human) protein peptidyl-prolyl isomerization [GO:0000413]; regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901407] GO:0000413; GO:0003723; GO:0003755; GO:0005634; GO:0005654; GO:0005829; GO:1901407 4700 XM_029347937.2 0 49 118 31 0 Q95LD9 3.33e-41 Aryl hydrocarbon receptor (Ah receptor) (AhR) Delphinapterus leucas (Beluga whale) cAMP-mediated signaling [GO:0019933]; cell cycle [GO:0007049]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; circadian regulation of gene expression [GO:0032922]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of T cell mediated immune response to tumor cell [GO:0002841]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of adaptive immune response [GO:0002819]; regulation of B cell proliferation [GO:0030888]; response to toxic substance [GO:0009636]; response to xenobiotic stimulus [GO:0009410] GO:0001094; GO:0001223; GO:0002819; GO:0002841; GO:0004879; GO:0005634; GO:0005737; GO:0005829; GO:0007049; GO:0009410; GO:0009636; GO:0017025; GO:0019933; GO:0030888; GO:0032922; GO:0034753; GO:0045892; GO:0045893; GO:0045944; GO:0046982; GO:0051879; GO:0060090; GO:0061629; GO:0070888; GO:0071320; GO:1904322; GO:1904613; GO:1990837 4701 XM_029356241.2 786 678 637 534 1488 P23640 3.43e-98 Ras-related protein Rab-27A (Rab-27) (EC 3.6.5.2) (GTP-binding protein Ram) (Ram p25) Rattus norvegicus (Rat) antigen processing and presentation [GO:0019882]; blood coagulation [GO:0007596]; complement-dependent cytotoxicity [GO:0097278]; cytotoxic T cell degranulation [GO:0043316]; exocytosis [GO:0006887]; exosomal secretion [GO:1990182]; melanocyte differentiation [GO:0030318]; melanosome localization [GO:0032400]; melanosome transport [GO:0032402]; multivesicular body organization [GO:0036257]; multivesicular body sorting pathway [GO:0071985]; natural killer cell degranulation [GO:0043320]; pigment granule localization [GO:0051875]; pigment granule transport [GO:0051904]; pigmentation [GO:0043473]; positive regulation of constitutive secretory pathway [GO:1903435]; positive regulation of exocytosis [GO:0045921]; positive regulation of gene expression [GO:0010628]; positive regulation of phagocytosis [GO:0050766]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of regulated secretory pathway [GO:1903307]; protein targeting [GO:0006605]; vesicle-mediated transport [GO:0016192] GO:0001750; GO:0003924; GO:0003925; GO:0005525; GO:0005764; GO:0005770; GO:0005794; GO:0006605; GO:0006887; GO:0007596; GO:0010628; GO:0016192; GO:0016324; GO:0019003; GO:0019882; GO:0019904; GO:0030141; GO:0030318; GO:0030425; GO:0030667; GO:0031489; GO:0032400; GO:0032402; GO:0032585; GO:0033093; GO:0036257; GO:0042470; GO:0043316; GO:0043320; GO:0043473; GO:0045921; GO:0050766; GO:0051875; GO:0051904; GO:0070382; GO:0071985; GO:0097278; GO:1903307; GO:1903428; GO:1903435; GO:1990182 4702 XM_044308210.1 177 107 146 184 242 Q9Z173 1.9e-74 Adhesion G protein-coupled receptor L3 (Calcium-independent alpha-latrotoxin receptor 3) (CIRL-3) (Latrophilin-3) Rattus norvegicus (Rat) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; brain development [GO:0007420]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; locomotion involved in locomotory behavior [GO:0031987]; maintenance of postsynaptic specialization structure [GO:0098880]; neuron migration [GO:0001764]; positive regulation of synapse assembly [GO:0051965]; response to cocaine [GO:0042220]; synapse assembly [GO:0007416]; synapse organization [GO:0050808] GO:0001764; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007166; GO:0007189; GO:0007416; GO:0007420; GO:0030246; GO:0030424; GO:0031987; GO:0042220; GO:0045211; GO:0050808; GO:0051965; GO:0098685; GO:0098742; GO:0098880; GO:0098978 4703 XM_044315071.1 8 5 21 4 17 NA NA NA NA NA NA 4704 XR_006394618.1 29 0 14 2 1 NA NA NA NA NA NA 4705 XM_029331525.2 0 163 56 39 15 Q96JM7 8.32e-130 Lethal(3)malignant brain tumor-like protein 3 (H-l(3)mbt-like protein 3) (L(3)mbt-like protein 3) (L3mbt-like 3) (MBT-1) Homo sapiens (Human) chromatin organization [GO:0006325]; erythrocyte maturation [GO:0043249]; granulocyte differentiation [GO:0030851]; macrophage differentiation [GO:0030225]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; regulation of DNA methylation-dependent heterochromatin formation [GO:0090308] GO:0003682; GO:0005634; GO:0005654; GO:0005730; GO:0006325; GO:0008270; GO:0030225; GO:0030851; GO:0042393; GO:0042802; GO:0043249; GO:0045892; GO:0090308; GO:0140034; GO:2000060 4706 XM_029334188.2 1435 983 837 1272 1037 Q7ZYQ3 1.92e-123 Choline/ethanolaminephosphotransferase 1 (EC 2.7.8.1) (EC 2.7.8.2) (1-alkenyl-2-acylglycerol choline phosphotransferase) (EC 2.7.8.22) Xenopus laevis (African clawed frog) phosphatidylethanolamine biosynthetic process [GO:0006646] GO:0004142; GO:0004307; GO:0005789; GO:0006646; GO:0031965; GO:0046872; GO:0047359 4707 XM_029341978.2 522 485 601 708 996 P43141 9.6e-32 Beta-4C adrenergic receptor (Beta-4C adrenoreceptor) (Beta-4C adrenoceptor) Meleagris gallopavo (Wild turkey) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; positive regulation of heart contraction [GO:0045823] GO:0004940; GO:0005886; GO:0007189; GO:0045823 4708 XM_029335714.2 34 648 763 1499 1425 Q9NZM1 0 Myoferlin (Fer-1-like protein 3) Homo sapiens (Human) blood circulation [GO:0008015]; membrane fusion [GO:0061025]; muscle contraction [GO:0006936]; plasma membrane organization [GO:0007009]; plasma membrane repair [GO:0001778]; T-tubule organization [GO:0033292] GO:0001778; GO:0005543; GO:0005635; GO:0005886; GO:0005901; GO:0006936; GO:0007009; GO:0008015; GO:0030659; GO:0031410; GO:0031965; GO:0033292; GO:0043231; GO:0046872; GO:0061025; GO:0070062 4709 XR_006396062.1 109 306 85 249 206 NA NA NA NA NA NA 4710 XM_029346329.2 14 0 9 6 29 NA NA NA NA NA NA 4711 XM_044317187.1 47 1 191 159 558 NA NA NA NA NA NA 4712 XM_044317204.1 0 352 0 0 0 Q6DCD5 0 Protein O-mannosyl-transferase TMTC2 (EC 2.4.1.109) (Transmembrane and TPR repeat-containing protein 2) Xenopus laevis (African clawed frog) protein O-linked mannosylation [GO:0035269] GO:0000030; GO:0004169; GO:0005783; GO:0016020; GO:0035269 4713 XM_029333119.2 1012 640 367 692 636 Q8IY84 2.05e-162 Serine/threonine-protein kinase NIM1 (EC 2.7.11.1) (NIM1 serine/threonine-protein kinase) Homo sapiens (Human) cellular response to glucose starvation [GO:0042149]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468] GO:0000287; GO:0004674; GO:0005524; GO:0006468; GO:0035556; GO:0042149; GO:0106310 4714 XM_029356696.2 18 0 2 1 40 NA NA NA NA NA NA 4715 XM_044313712.1 36 11 5 15 42 NA NA NA NA NA NA 4716 XM_044315641.1 37 4 5 4 0 Q96MB7 7.52e-42 Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease) Homo sapiens (Human) NA GO:0004518; GO:0005634; GO:0005829; GO:0005886; GO:0034451; GO:0046872 4717 XM_029340268.2 0 6 0 0 0 P11009 3.38e-99 Creatine kinase S-type, mitochondrial (EC 2.7.3.2) (Basic-type mitochondrial creatine kinase) (Mib-CK) (Sarcomeric mitochondrial creatine kinase) (S-MtCK) Gallus gallus (Chicken) phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310] GO:0004111; GO:0005524; GO:0005743; GO:0016310; GO:0046314 4718 XM_029356366.2 249 174 98 141 90 P55112 5.04e-37 Zinc metalloproteinase nas-4 (EC 3.4.24.-) (Nematode astacin 4) Caenorhabditis elegans proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0006508; GO:0008270 4719 XR_006393163.1 47 22 71 78 96 NA NA NA NA NA NA 4720 XM_029336874.2 743 447 509 775 1034 Q9BX63 0 Fanconi anemia group J protein (Protein FACJ) (EC 3.6.4.13) (ATP-dependent RNA helicase BRIP1) (BRCA1-associated C-terminal helicase 1) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1) Homo sapiens (Human) cellular response to angiotensin [GO:1904385]; cellular response to hypoxia [GO:0071456]; cellular response to vitamin [GO:0071295]; chiasma assembly [GO:0051026]; DNA damage checkpoint signaling [GO:0000077]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair involved in meiotic recombination [GO:1990918]; homologous recombination [GO:0035825]; meiotic DNA double-strand break processing involved in reciprocal meiotic recombination [GO:0010705]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; nucleotide-excision repair [GO:0006289]; regulation of transcription by RNA polymerase II [GO:0006357]; response to toxic substance [GO:0009636]; seminiferous tubule development [GO:0072520]; spermatid development [GO:0007286]; spermatogonial cell division [GO:0007284] GO:0000077; GO:0003677; GO:0003678; GO:0003682; GO:0003724; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0006281; GO:0006289; GO:0006302; GO:0006357; GO:0007284; GO:0007286; GO:0008285; GO:0009636; GO:0010629; GO:0010705; GO:0016887; GO:0031965; GO:0035825; GO:0043139; GO:0046872; GO:0051026; GO:0051539; GO:0070532; GO:0071295; GO:0071456; GO:0072520; GO:1904385; GO:1990918 4721 XM_029357755.2 0 228 0 3 17 Q8AYG3 6.32e-92 Dual specificity protein kinase Ttk (EC 2.7.12.1) (Mitotic checkpoint serine/threonine-protein kinase Mps1) (Monopolar spindle protein 1) (Protein nightcap) Danio rerio (Zebrafish) (Brachydanio rerio) anatomical structure homeostasis [GO:0060249]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; female meiosis chromosome segregation [GO:0016321]; fin regeneration [GO:0031101]; male meiosis chromosome segregation [GO:0007060]; meiotic spindle assembly checkpoint signaling [GO:0033316]; mitotic spindle assembly checkpoint signaling [GO:0007094]; negative regulation of exit from mitosis [GO:0001100]; peptidyl-serine phosphorylation [GO:0018105]; protein localization to kinetochore [GO:0034501]; tissue regeneration [GO:0042246] GO:0000776; GO:0001100; GO:0004674; GO:0004712; GO:0004713; GO:0005524; GO:0005634; GO:0007059; GO:0007060; GO:0007094; GO:0016321; GO:0018105; GO:0031101; GO:0033316; GO:0034501; GO:0042246; GO:0046872; GO:0051301; GO:0060249; GO:0106310 4722 XM_029329507.2 18304 20063 13006 16140 18010 R1CW23 3.8e-113 Dimethylsulfonioproprionate lyase 7 (DMSP lyase 7) (EC 4.4.1.3) (Dimethylpropiothetin dethiomethylase 7) Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi) NA GO:0047869 4723 XR_006396876.1 121 70 50 23 38 NA NA NA NA NA NA 4724 XM_029345891.2 0 0 57 161 0 Q059U7 1.33e-157 Protein inturned (Inturned planar cell polarity effector homolog) (PDZ domain-containing protein 6) Mus musculus (Mouse) cell division [GO:0051301]; cilium assembly [GO:0060271]; embryonic digit morphogenesis [GO:0042733]; establishment of planar polarity [GO:0001736]; hair follicle morphogenesis [GO:0031069]; intraciliary transport [GO:0042073]; keratinocyte differentiation [GO:0030216]; limb development [GO:0060173]; motile cilium assembly [GO:0044458]; negative regulation of cell division [GO:0051782]; negative regulation of keratinocyte proliferation [GO:0010839]; nervous system development [GO:0007399]; neural tube development [GO:0021915]; non-motile cilium assembly [GO:1905515]; positive regulation of smoothened signaling pathway [GO:0045880]; protein localization to organelle [GO:0033365]; regulation of cilium assembly [GO:1902017]; regulation of ossification [GO:0030278]; regulation of smoothened signaling pathway [GO:0008589]; roof of mouth development [GO:0060021]; smoothened signaling pathway [GO:0007224]; spinal cord dorsal/ventral patterning [GO:0021513]; tongue morphogenesis [GO:0043587]; vesicle-mediated transport [GO:0016192] GO:0001736; GO:0005737; GO:0005814; GO:0005929; GO:0007224; GO:0007399; GO:0008589; GO:0009986; GO:0010839; GO:0016192; GO:0021513; GO:0021915; GO:0030216; GO:0030278; GO:0031069; GO:0031514; GO:0033365; GO:0035869; GO:0036064; GO:0042073; GO:0042733; GO:0043587; GO:0044458; GO:0045880; GO:0051301; GO:0051782; GO:0060021; GO:0060173; GO:0060271; GO:1902017; GO:1905515 4725 XR_003824772.2 354 74 235 168 431 P62997 4.09e-43 Transformer-2 protein homolog beta (TRA-2 beta) (TRA2-beta) (RA301) (Splicing factor, arginine/serine-rich 10) (Transformer-2 protein homolog B) Rattus norvegicus (Rat) cellular response to glucose stimulus [GO:0071333]; cerebral cortex regionalization [GO:0021796]; embryonic brain development [GO:1990403]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of RNA splicing [GO:0043484]; response to reactive oxygen species [GO:0000302] GO:0000302; GO:0000381; GO:0000398; GO:0001673; GO:0003723; GO:0003729; GO:0005634; GO:0005637; GO:0005681; GO:0019904; GO:0021796; GO:0032991; GO:0036002; GO:0042802; GO:0043484; GO:0048026; GO:0048471; GO:0071333; GO:1990403 4726 XR_006395515.1 5 122 7 115 41 NA NA NA NA NA NA 4727 XM_029328761.2 871 376 490 772 641 Q5PPV3 6.72e-96 MORN repeat-containing protein 3 Xenopus laevis (African clawed frog) NA NA 4728 XM_029342649.2 1 5 0 6 4 NA NA NA NA NA NA 4729 XR_006395314.1 43 83 27 102 12 NA NA NA NA NA NA 4730 XM_029340504.2 0 0 0 79 0 Q5XIN7 2.52e-172 Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGnT1) (EC 2.4.1.-) Rattus norvegicus (Rat) O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493] GO:0000139; GO:0006493; GO:0008375; GO:0016020; GO:0016266; GO:0030145; GO:0047223 4731 XM_029357476.2 218 263 88 284 256 NA NA NA NA NA NA 4732 XM_029346606.2 1691 1108 816 554 610 NA NA NA NA NA NA 4733 XM_044313769.1 99 12 57 82 50 Q567B1 1.59e-85 Ubiquitin thioesterase OTU1 (EC 3.4.19.12) Danio rerio (Zebrafish) (Brachydanio rerio) endoplasmic reticulum unfolded protein response [GO:0030968]; macroautophagy [GO:0016236]; protein deubiquitination [GO:0016579]; protein K11-linked deubiquitination [GO:0035871]; protein K27-linked deubiquitination [GO:1990167]; protein K29-linked deubiquitination [GO:0035523]; protein K33-linked deubiquitination [GO:1990168]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0004843; GO:0005737; GO:0016236; GO:0016579; GO:0030433; GO:0030968; GO:0035523; GO:0035871; GO:0046872; GO:0070536; GO:0071108; GO:1990167; GO:1990168 4734 XM_044308051.1 1207 1084 919 1493 1710 P42356 0 Phosphatidylinositol 4-kinase alpha (PI4-kinase alpha) (PI4K-alpha) (PtdIns-4-kinase alpha) (EC 2.7.1.67) (Phosphatidylinositol 4-Kinase III alpha) Homo sapiens (Human) modulation by host of viral process [GO:0044788]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol phosphate biosynthetic process [GO:0046854]; phosphatidylinositol-mediated signaling [GO:0048015]; phosphorylation [GO:0016310]; reorganization of cellular membranes to establish viral sites of replication [GO:0140754]; signal transduction [GO:0007165] GO:0004430; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0005925; GO:0006661; GO:0007165; GO:0016020; GO:0016301; GO:0016310; GO:0030660; GO:0044788; GO:0045296; GO:0046854; GO:0048015; GO:0052742; GO:0070062; GO:0140754 4735 XR_006393375.1 8 9 2 34 0 NA NA NA NA NA NA 4736 XM_044324476.1 0 34 59 83 32 Q63570 0 26S proteasome regulatory subunit 6B (26S proteasome AAA-ATPase subunit RPT3) (Proteasome 26S subunit ATPase 4) (S6 ATPase) (Tat-binding protein 7) (TBP-7) Rattus norvegicus (Rat) blastocyst development [GO:0001824]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] GO:0000502; GO:0001824; GO:0005524; GO:0005634; GO:0008540; GO:0016234; GO:0016887; GO:0022624; GO:0031597; GO:0036402; GO:0043161; GO:0045202 4737 XM_044310435.1 92 873 1267 11 228 NA NA NA NA NA NA 4738 XM_029353286.2 1268 910 851 1343 1064 P09215 0 Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta) [Cleaved into: Protein kinase C delta type regulatory subunit; Protein kinase C delta type catalytic subunit (Sphingosine-dependent protein kinase-1) (SDK1)] Rattus norvegicus (Rat) activation of protein kinase activity [GO:0032147]; aging [GO:0007568]; apoptotic process [GO:0006915]; B cell proliferation [GO:0042100]; cell chemotaxis [GO:0060326]; cell cycle [GO:0007049]; cellular response to angiotensin [GO:1904385]; cellular response to glucose starvation [GO:0042149]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hydroperoxide [GO:0071447]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular senescence [GO:0090398]; collagen metabolic process [GO:0032963]; D-aspartate import across plasma membrane [GO:0070779]; defense response to bacterium [GO:0042742]; immunoglobulin mediated immune response [GO:0016064]; intracellular signal transduction [GO:0035556]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of filopodium assembly [GO:0051490]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of peptidyl-tyrosine phosphorylation [GO:0050732]; negative regulation of platelet aggregation [GO:0090331]; neutrophil activation [GO:0042119]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of endodeoxyribonuclease activity [GO:0032079]; positive regulation of glucose import [GO:0046326]; positive regulation of glucosylceramide catabolic process [GO:2000753]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of phospholipid scramblase activity [GO:1900163]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of response to DNA damage stimulus [GO:2001022]; positive regulation of sphingomyelin catabolic process [GO:2000755]; positive regulation of superoxide anion generation [GO:0032930]; post-translational protein modification [GO:0043687]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of ceramide biosynthetic process [GO:2000303]; regulation of phosphorylation [GO:0042325]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; response to organic cyclic compound [GO:0014070]; response to organonitrogen compound [GO:0010243]; response to oxidative stress [GO:0006979]; response to xenobiotic stimulus [GO:0009410]; termination of signal transduction [GO:0023021] GO:0001666; GO:0004672; GO:0004674; GO:0004697; GO:0004698; GO:0004699; GO:0004713; GO:0005524; GO:0005634; GO:0005737; GO:0005739; GO:0005783; GO:0005829; GO:0005886; GO:0005911; GO:0006468; GO:0006915; GO:0006979; GO:0007049; GO:0007568; GO:0008047; GO:0009408; GO:0009410; GO:0009612; GO:0009749; GO:0010243; GO:0014070; GO:0016020; GO:0016064; GO:0016363; GO:0018105; GO:0018107; GO:0019899; GO:0019900; GO:0019901; GO:0023021; GO:0030837; GO:0032079; GO:0032147; GO:0032869; GO:0032930; GO:0032956; GO:0032963; GO:0034351; GO:0034599; GO:0034644; GO:0035307; GO:0035556; GO:0036019; GO:0042100; GO:0042119; GO:0042149; GO:0042307; GO:0042325; GO:0042542; GO:0042742; GO:0043065; GO:0043200; GO:0043406; GO:0043407; GO:0043410; GO:0043560; GO:0043687; GO:0045471; GO:0046326; GO:0046627; GO:0046777; GO:0046872; GO:0048471; GO:0050732; GO:0051490; GO:0060326; GO:0070301; GO:0070779; GO:0070976; GO:0071447; GO:0090331; GO:0090398; GO:0099524; GO:0106310; GO:1900163; GO:1904385; GO:2000303; GO:2000304; GO:2000753; GO:2000755; GO:2001022; GO:2001235 4739 XM_044322455.1 118 35 13 116 70 Q96AY4 4.08e-97 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4740 XM_044322455.1 118 35 13 116 70 Q96AY4 1.56e-96 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4741 XM_044322455.1 118 35 13 116 70 Q96AY4 5.37e-89 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4742 XM_044322455.1 118 35 13 116 70 Q96AY4 7.44e-78 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4743 XM_044322455.1 118 35 13 116 70 Q96AY4 3.73e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4744 XM_044325252.1 8 1 0 1 14 NA NA NA NA NA NA 4745 XM_044317359.1 478 357 278 292 495 NA NA NA NA NA NA 4746 XM_044315483.1 327 194 106 75 82 NA NA NA NA NA NA 4747 XM_044307514.1 0 4 0 0 6 NA NA NA NA NA NA 4748 XM_029324807.2 0 0 0 0 112 P98198 0 Phospholipid-transporting ATPase ID (EC 7.6.2.1) (ATPase class I type 8B member 2) (P4-ATPase flippase complex alpha subunit ATP8B2) Homo sapiens (Human) Golgi organization [GO:0007030]; ion transmembrane transport [GO:0034220]; phospholipid translocation [GO:0045332] GO:0000287; GO:0005524; GO:0005730; GO:0005789; GO:0005794; GO:0005802; GO:0005829; GO:0005886; GO:0007030; GO:0016887; GO:0034220; GO:0045332; GO:0090554; GO:0140326; GO:0140345; GO:1990531 4749 XM_029334207.2 100 50 39 65 51 Q15915 9.46e-89 Zinc finger protein ZIC 1 (Zinc finger protein 201) (Zinc finger protein of the cerebellum 1) Homo sapiens (Human) adult walking behavior [GO:0007628]; brain development [GO:0007420]; cell differentiation [GO:0030154]; central nervous system development [GO:0007417]; hippocampus development [GO:0021766]; inner ear morphogenesis [GO:0042472]; maintenance of cell number [GO:0098727]; olfactory bulb development [GO:0021772]; pattern specification process [GO:0007389]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of protein import into nucleus [GO:0042307]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription by RNA polymerase II [GO:0006357]; spinal cord development [GO:0021510] GO:0000978; GO:0000981; GO:0001228; GO:0003700; GO:0005634; GO:0005654; GO:0005737; GO:0006357; GO:0007389; GO:0007417; GO:0007420; GO:0007628; GO:0008589; GO:0021510; GO:0021766; GO:0021772; GO:0030154; GO:0042307; GO:0042472; GO:0045893; GO:0046872; GO:0098727; GO:1990837 4750 XM_029323677.2 2056 1434 1185 1835 1511 P50749 2.19e-32 Ras association domain-containing protein 2 Homo sapiens (Human) bone remodeling [GO:0046849]; cell cycle [GO:0007049]; epidermal growth factor receptor signaling pathway via I-kappaB kinase/NF-kappaB cascade [GO:0038168]; homeostasis of number of cells [GO:0048872]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; ossification [GO:0001503]; positive regulation of apoptotic process [GO:0043065]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase activity [GO:0045860]; protein stabilization [GO:0050821]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoclast differentiation [GO:0045670]; signal transduction [GO:0007165]; skeletal system development [GO:0001501] GO:0000776; GO:0001501; GO:0001503; GO:0004672; GO:0005634; GO:0005654; GO:0005737; GO:0005794; GO:0005829; GO:0005886; GO:0007049; GO:0007165; GO:0031954; GO:0032991; GO:0033137; GO:0038168; GO:0043065; GO:0045667; GO:0045670; GO:0045860; GO:0046330; GO:0046849; GO:0048872; GO:0050821; GO:1901222; GO:1901223 4751 XM_044312729.1 3338 2112 1859 4263 3627 Q68FX0 9.49e-133 Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial (Isocitric dehydrogenase subunit beta) (NAD(+)-specific ICDH subunit beta) Rattus norvegicus (Rat) 2-oxoglutarate metabolic process [GO:0006103]; isocitrate metabolic process [GO:0006102]; NADH metabolic process [GO:0006734]; tricarboxylic acid cycle [GO:0006099] GO:0000287; GO:0004449; GO:0005739; GO:0005962; GO:0006099; GO:0006102; GO:0006103; GO:0006734; GO:0051287 4752 XM_044308897.1 0 0 0 22 10 P07949 3.26e-69 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; axon guidance [GO:0007411]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; lymphocyte migration into lymphoid organs [GO:0097021]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; posterior midgut development [GO:0007497]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006468; GO:0006919; GO:0007156; GO:0007158; GO:0007165; GO:0007169; GO:0007411; GO:0007497; GO:0009410; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0038023; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0097021; GO:0098797; GO:2001241 4753 XM_029328963.2 154 49 32 37 240 O88696 7.02e-98 ATP-dependent Clp protease proteolytic subunit, mitochondrial (EC 3.4.21.92) (Endopeptidase Clp) Mus musculus (Mouse) membrane protein proteolysis [GO:0033619]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603] GO:0004175; GO:0004176; GO:0004252; GO:0005739; GO:0005759; GO:0006508; GO:0006515; GO:0009368; GO:0033619; GO:0042802; GO:0051117; GO:0051603 4754 XM_029337191.2 4 10 1 11 26 NA NA NA NA NA NA 4755 XM_044320191.1 0 0 36 13 0 Q5AF03 2.74e-29 Glyoxalase 3 (EC 4.2.1.130) (Glutathione-independent glyoxalase) Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243] GO:0005737; GO:0019172; GO:0019243; GO:0030445; GO:0030446; GO:0062040 4756 XR_006397961.1 1 0 0 6 0 NA NA NA NA NA NA 4757 XM_029338770.2 342 231 161 222 299 P42325 3.75e-104 Neurocalcin homolog (DrosNCa) Drosophila melanogaster (Fruit fly) negative regulation of neuronal signal transduction [GO:1902848]; positive regulation of circadian sleep/wake cycle, sleep [GO:0045938] GO:0005509; GO:0045938; GO:1902848 4758 XM_044319883.1 376 241 243 188 169 NA NA NA NA NA NA 4759 XM_044311841.1 0 0 6 0 2 Q96AY4 2.81e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4760 XM_044318771.1 4 2 9 2 4 NA NA NA NA NA NA 4761 XM_029332970.2 60 89 91 55 84 Q5XGD7 1.12e-29 Transmembrane protein 45B Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0016020 4762 XM_029337756.2 3143 1559 1724 2539 2689 P14866 4.49e-60 Heterogeneous nuclear ribonucleoprotein L (hnRNP L) Homo sapiens (Human) cellular response to amino acid starvation [GO:0034198]; circadian rhythm [GO:0007623]; mRNA processing [GO:0006397]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of mRNA binding [GO:1902416]; positive regulation of translation [GO:0045727]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of RNA splicing [GO:0043484]; response to peptide [GO:1901652]; RNA processing [GO:0006396] GO:0000381; GO:0000785; GO:0000976; GO:0003723; GO:0003729; GO:0003730; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006396; GO:0006397; GO:0007623; GO:0016020; GO:0034198; GO:0035770; GO:0043484; GO:0045727; GO:0045892; GO:0048025; GO:0048471; GO:0070062; GO:0097157; GO:1901652; GO:1902416; GO:1990715; GO:1990904 4763 XM_029337756.2 3143 1559 1724 2539 2689 P14866 2.15e-42 Heterogeneous nuclear ribonucleoprotein L (hnRNP L) Homo sapiens (Human) cellular response to amino acid starvation [GO:0034198]; circadian rhythm [GO:0007623]; mRNA processing [GO:0006397]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of mRNA binding [GO:1902416]; positive regulation of translation [GO:0045727]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of RNA splicing [GO:0043484]; response to peptide [GO:1901652]; RNA processing [GO:0006396] GO:0000381; GO:0000785; GO:0000976; GO:0003723; GO:0003729; GO:0003730; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006396; GO:0006397; GO:0007623; GO:0016020; GO:0034198; GO:0035770; GO:0043484; GO:0045727; GO:0045892; GO:0048025; GO:0048471; GO:0070062; GO:0097157; GO:1901652; GO:1902416; GO:1990715; GO:1990904 4764 XM_029352055.2 140 159 97 264 353 NA NA NA NA NA NA 4765 XM_029356010.2 45 0 31 76 21 Q866A2 1.99e-81 Neuronal acetylcholine receptor subunit alpha-7 Macaca mulatta (Rhesus macaque) associative learning [GO:0008306]; B cell activation [GO:0042113]; behavioral response to ethanol [GO:0048149]; behavioral response to nicotine [GO:0035095]; calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; cognition [GO:0050890]; dendrite arborization [GO:0140059]; dendritic spine organization [GO:0097061]; endocytosis [GO:0006897]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; generation of ovulation cycle rhythm [GO:0060112]; ion transmembrane transport [GO:0034220]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of tumor necrosis factor production [GO:0032720]; nervous system process [GO:0050877]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of CoA-transferase activity [GO:1905920]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure [GO:0001988]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; regulation of amyloid fibril formation [GO:1905906]; regulation of membrane potential [GO:0042391]; regulation of neuron death [GO:1901214]; regulation of norepinephrine secretion [GO:0014061]; regulation of synaptic transmission, dopaminergic [GO:0032225]; response to amyloid-beta [GO:1904645]; response to cold [GO:0009409]; response to food [GO:0032094]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; sensory processing [GO:0050893]; short-term memory [GO:0007614]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271]; T cell activation [GO:0042110] GO:0001540; GO:0001666; GO:0001933; GO:0001988; GO:0005231; GO:0005886; GO:0005892; GO:0006816; GO:0006874; GO:0006897; GO:0007165; GO:0007268; GO:0007271; GO:0007614; GO:0008284; GO:0008306; GO:0009409; GO:0009897; GO:0014061; GO:0015464; GO:0015643; GO:0016324; GO:0017081; GO:0022848; GO:0030317; GO:0030594; GO:0030673; GO:0032094; GO:0032225; GO:0032691; GO:0032715; GO:0032720; GO:0033138; GO:0034220; GO:0035094; GO:0035095; GO:0042110; GO:0042113; GO:0042166; GO:0042391; GO:0042734; GO:0042803; GO:0043005; GO:0043410; GO:0045202; GO:0045766; GO:0048149; GO:0050728; GO:0050877; GO:0050890; GO:0050893; GO:0051649; GO:0060112; GO:0070374; GO:0097061; GO:0098839; GO:0098978; GO:0098981; GO:0140059; GO:1900273; GO:1901214; GO:1902004; GO:1904315; GO:1904645; GO:1905906; GO:1905920; GO:2000463 4766 XM_029327130.2 576 474 418 683 524 Q4KWL2 8.47e-26 Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor) Tscherskia triton (Greater long-tailed hamster) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; blood vessel diameter maintenance [GO:0097746]; positive regulation of autophagosome maturation [GO:1901098]; positive regulation of lipophagy [GO:1904504]; regulation of smooth muscle contraction [GO:0006940] GO:0004941; GO:0005769; GO:0005794; GO:0005886; GO:0006940; GO:0007189; GO:0097746; GO:1901098; GO:1904504 4767 XM_044321685.1 924 577 452 530 251 P69478 7.63e-40 Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4S-1) (C4ST-1) (C4ST1) Rattus norvegicus (Rat) apoptotic process [GO:0006915]; carbohydrate biosynthetic process [GO:0016051]; cartilage development [GO:0051216]; chondrocyte development [GO:0002063]; chondroitin sulfate biosynthetic process [GO:0030206]; chondroitin sulfate metabolic process [GO:0030204]; developmental growth [GO:0048589]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; embryonic viscerocranium morphogenesis [GO:0048703]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; polysaccharide localization [GO:0033037]; post-anal tail morphogenesis [GO:0036342]; post-embryonic development [GO:0009791]; proteoglycan biosynthetic process [GO:0030166]; regulation of cell population proliferation [GO:0042127]; respiratory gaseous exchange by respiratory system [GO:0007585]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0000139; GO:0001537; GO:0001701; GO:0002063; GO:0006915; GO:0007179; GO:0007585; GO:0008146; GO:0009791; GO:0016051; GO:0030166; GO:0030204; GO:0030206; GO:0030326; GO:0030512; GO:0033037; GO:0036342; GO:0042127; GO:0042733; GO:0043066; GO:0047756; GO:0048589; GO:0048703; GO:0048704; GO:0050659; GO:0051216 4768 XM_029323929.2 459 451 221 219 246 P27808 1.83e-142 Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (EC 2.4.1.101) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I) (GNT-I) (GlcNAc-T I) Mus musculus (Mouse) in utero embryonic development [GO:0001701]; protein glycosylation [GO:0006486]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279]; UDP-N-acetylglucosamine catabolic process [GO:0006049] GO:0000139; GO:0001701; GO:0003827; GO:0005794; GO:0006049; GO:0006486; GO:0006487; GO:0008375; GO:0018279; GO:0030145; GO:0048471 4769 XM_044308533.1 13 6 6 38 12 NA NA NA NA NA NA 4770 XM_029333328.2 85 292 206 372 259 NA NA NA NA NA NA 4771 XM_029348097.2 46 0 12 59 78 O89103 1.45e-22 Complement component C1q receptor (C1q/MBL/SPA receptor) (C1qR(p)) (C1qRp) (Cell surface antigen AA4) (Complement component 1 q subcomponent receptor 1) (Lymphocyte antigen 68) (Ly-68) (CD antigen CD93) Mus musculus (Mouse) cell-cell adhesion [GO:0098609] GO:0001849; GO:0005509; GO:0005886; GO:0009986; GO:0030246; GO:0031410; GO:0098609 4772 XM_044307169.1 54 12 27 16 17 NA NA NA NA NA NA 4773 XM_029348750.2 502 533 367 510 457 Q96CM3 2.63e-47 Pseudouridylate synthase RPUSD4, mitochondrial (EC 5.4.99.-) (RNA pseudouridylate synthase domain-containing protein 4) Homo sapiens (Human) enzyme-directed rRNA pseudouridine synthesis [GO:0000455]; mitochondrial tRNA pseudouridine synthesis [GO:0070902]; mRNA processing [GO:0006397]; mRNA pseudouridine synthesis [GO:1990481]; positive regulation of mitochondrial translation [GO:0070131]; RNA splicing [GO:0008380] GO:0000049; GO:0000455; GO:0003723; GO:0005654; GO:0005739; GO:0005759; GO:0006397; GO:0008380; GO:0009982; GO:0035770; GO:0070131; GO:0070902; GO:1990400; GO:1990481 4774 XM_044316747.1 0 20 4 0 12 NA NA NA NA NA NA 4775 XM_029342109.2 50 57 14 23 34 NA NA NA NA NA NA 4776 XM_029330258.2 107 99 101 258 201 NA NA NA NA NA NA 4777 XM_029358367.2 4695 4098 2683 4114 2837 Q28G26 0 Phosphatidylinositol 4-kinase type 2-beta (EC 2.7.1.67) (Phosphatidylinositol 4-kinase type II-beta) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) phosphatidylinositol phosphate biosynthetic process [GO:0046854]; phosphorylation [GO:0016310] GO:0000139; GO:0004430; GO:0005524; GO:0005789; GO:0005829; GO:0005886; GO:0016310; GO:0031901; GO:0046854 4778 XM_044328914.1 10 14 26 5 14 NA NA NA NA NA NA 4779 XM_044320712.1 60 21 14 2 0 NA NA NA NA NA NA 4780 XM_029346056.2 31249 30626 18330 28965 18109 Q91WV7 5.25e-98 Neutral and basic amino acid transport protein rBAT (Solute carrier family 3 member 1) (b(0,+)-type amino acid transport protein) (NBAT) Mus musculus (Mouse) amino acid transport [GO:0006865]; aspartate transmembrane transport [GO:0015810]; carbohydrate metabolic process [GO:0005975]; gene expression [GO:0010467]; L-cystine transport [GO:0015811]; L-glutamate transmembrane transport [GO:0015813] GO:0005743; GO:0005774; GO:0005886; GO:0005975; GO:0006865; GO:0010467; GO:0015810; GO:0015811; GO:0015813; GO:0016324; GO:0031526; GO:0044877; GO:0046982 4781 XM_044326736.1 89 0 8 64 7 NA NA NA NA NA NA 4782 XM_029353507.2 937 50 83 80 38 NA NA NA NA NA NA 4783 XR_006392649.1 9 0 5 36 26 NA NA NA NA NA NA 4784 XM_029352402.2 325 0 116 179 325 Q9H267 1.41e-177 Vacuolar protein sorting-associated protein 33B (hVPS33B) Homo sapiens (Human) collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; endosome organization [GO:0007032]; intracellular protein transport [GO:0006886]; intracellular transport [GO:0046907]; lysosome localization [GO:0032418]; megakaryocyte development [GO:0035855]; melanosome localization [GO:0032400]; membrane fusion [GO:0061025]; peptidyl-lysine hydroxylation [GO:0017185]; phagosome-lysosome fusion [GO:0090385]; platelet alpha granule organization [GO:0070889]; protein transport [GO:0015031]; regulation of platelet aggregation [GO:0090330]; vesicle-mediated transport [GO:0016192] GO:0005737; GO:0005764; GO:0005765; GO:0005768; GO:0005770; GO:0005773; GO:0005794; GO:0005829; GO:0006886; GO:0007032; GO:0010008; GO:0015031; GO:0016192; GO:0017185; GO:0030136; GO:0030199; GO:0030897; GO:0031091; GO:0031901; GO:0031902; GO:0032400; GO:0032418; GO:0032963; GO:0033263; GO:0035855; GO:0044877; GO:0046907; GO:0048471; GO:0055037; GO:0061025; GO:0070889; GO:0090330; GO:0090385; GO:0099023 4785 XR_006395258.1 347 152 147 55 61 NA NA NA NA NA NA 4786 XR_006395368.1 12 31 46 53 46 NA NA NA NA NA NA 4787 XM_044308563.1 640 1326 914 830 635 NA NA NA NA NA NA 4788 XM_029332919.2 6253 6991 5072 12100 8641 P49024 5.92e-149 Paxillin Gallus gallus (Chicken) endothelial cell migration [GO:0043542]; response to muscle stretch [GO:0035994]; substrate adhesion-dependent cell spreading [GO:0034446]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001725; GO:0003712; GO:0005829; GO:0005886; GO:0005925; GO:0005938; GO:0007179; GO:0017166; GO:0034446; GO:0035994; GO:0043542; GO:0046872 4789 XM_029337129.2 458 448 741 673 232 NA NA NA NA NA NA 4790 XM_029347962.2 12 17 26 56 8 NA NA NA NA NA NA 4791 XM_044311401.1 13 7 13 11 7 Q09575 2.17e-30 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 4792 XR_006395480.1 62 107 59 4 108 NA NA NA NA NA NA 4793 XM_029350282.2 0 13 2 11 0 Q6L8F3 2.36e-32 NA NA NA NA 4794 XM_044309668.1 0 0 0 11 0 O16025 0 Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (AOS) (EC 4.2.1.-) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)] Plexaura homomalla (Black sea rod) arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; lipid oxidation [GO:0034440]; oxylipin biosynthetic process [GO:0031408] GO:0005506; GO:0005737; GO:0006633; GO:0009978; GO:0016020; GO:0019369; GO:0020037; GO:0031408; GO:0034440; GO:0047677 4795 XM_044326329.1 38 25 25 32 34 NA NA NA NA NA NA 4796 XM_044324349.1 197 78 176 143 157 NA NA NA NA NA NA 4797 XR_003825350.2 5619 8321 5619 5832 3853 NA NA NA NA NA NA 4798 XM_044321582.1 26 4 25 7 14 NA NA NA NA NA NA 4799 XR_006397971.1 170 11 92 11 438 NA NA NA NA NA NA 4800 XM_044324392.1 139 199 150 272 271 NA NA NA NA NA NA 4801 XM_029348350.2 1640 2087 1093 1495 1963 NA NA NA NA NA NA 4802 XM_044328062.1 358 244 354 403 345 Q90678 1.03e-74 Platelet-activating factor acetylhydrolase (PAF acetylhydrolase) (EC 3.1.1.47) (1-alkyl-2-acetylglycerophosphocholine esterase) (2-acetyl-1-alkylglycerophosphocholine esterase) (LDL-associated phospholipase A2) (LDL-PLA(2)) (PAF 2-acylhydrolase) Gallus gallus (Chicken) lipid catabolic process [GO:0016042] GO:0003847; GO:0005615; GO:0016042 4803 XM_044328640.1 557 101 199 431 594 A6QPM3 1.92e-85 Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.361) (PR domain zinc finger protein 6) (PR domain-containing protein 6) Bos taurus (Bovine) chromatin organization [GO:0006325]; histone methylation [GO:0016571]; regulation of gene expression [GO:0010468] GO:0005634; GO:0006325; GO:0010468; GO:0016571; GO:0046872; GO:0140944 4804 XR_003824880.2 10 23 14 33 13 NA NA NA NA NA NA 4805 XM_029329400.2 902 762 541 650 503 NA NA NA NA NA NA 4806 XM_029344883.2 159 0 0 122 0 NA NA NA NA NA NA 4807 XM_044317582.1 154 79 86 88 128 NA NA NA NA NA NA 4808 XM_029353529.2 591 496 500 834 1277 Q9BZH6 0 WD repeat-containing protein 11 (Bromodomain and WD repeat-containing protein 2) (WD repeat-containing protein 15) Homo sapiens (Human) cilium assembly [GO:0060271]; head development [GO:0060322]; heart development [GO:0007507]; intracellular protein transport [GO:0006886]; multicellular organism growth [GO:0035264]; regulation of smoothened signaling pathway [GO:0008589]; vesicle tethering to Golgi [GO:0099041] GO:0005634; GO:0005737; GO:0005765; GO:0005802; GO:0005829; GO:0005930; GO:0006886; GO:0007507; GO:0008589; GO:0015630; GO:0016020; GO:0031410; GO:0035264; GO:0036064; GO:0060271; GO:0060322; GO:0099041 4809 XM_044321562.1 60 0 0 0 0 Q059U7 1.64e-158 Protein inturned (Inturned planar cell polarity effector homolog) (PDZ domain-containing protein 6) Mus musculus (Mouse) cell division [GO:0051301]; cilium assembly [GO:0060271]; embryonic digit morphogenesis [GO:0042733]; establishment of planar polarity [GO:0001736]; hair follicle morphogenesis [GO:0031069]; intraciliary transport [GO:0042073]; keratinocyte differentiation [GO:0030216]; limb development [GO:0060173]; motile cilium assembly [GO:0044458]; negative regulation of cell division [GO:0051782]; negative regulation of keratinocyte proliferation [GO:0010839]; nervous system development [GO:0007399]; neural tube development [GO:0021915]; non-motile cilium assembly [GO:1905515]; positive regulation of smoothened signaling pathway [GO:0045880]; protein localization to organelle [GO:0033365]; regulation of cilium assembly [GO:1902017]; regulation of ossification [GO:0030278]; regulation of smoothened signaling pathway [GO:0008589]; roof of mouth development [GO:0060021]; smoothened signaling pathway [GO:0007224]; spinal cord dorsal/ventral patterning [GO:0021513]; tongue morphogenesis [GO:0043587]; vesicle-mediated transport [GO:0016192] GO:0001736; GO:0005737; GO:0005814; GO:0005929; GO:0007224; GO:0007399; GO:0008589; GO:0009986; GO:0010839; GO:0016192; GO:0021513; GO:0021915; GO:0030216; GO:0030278; GO:0031069; GO:0031514; GO:0033365; GO:0035869; GO:0036064; GO:0042073; GO:0042733; GO:0043587; GO:0044458; GO:0045880; GO:0051301; GO:0051782; GO:0060021; GO:0060173; GO:0060271; GO:1902017; GO:1905515 4810 XR_006397066.1 0 0 4 23 9 NA NA NA NA NA NA 4811 XM_044325176.1 913 705 502 556 49 NA NA NA NA NA NA 4812 XM_044312085.1 0 5 1 28 41 NA NA NA NA NA NA 4813 XM_029335758.2 1095 453 191 735 461 Q9TUP7 1.16e-33 Orexin receptor type 2 (Ox-2-R) (Ox2-R) (Ox2R) (Hypocretin receptor type 2) Canis lupus familiaris (Dog) (Canis familiaris) circadian sleep/wake cycle process [GO:0022410]; feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; locomotion [GO:0040011]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; regulation of circadian sleep/wake cycle, wakefulness [GO:0010840]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0004930; GO:0005886; GO:0007186; GO:0007200; GO:0007218; GO:0007631; GO:0010840; GO:0016499; GO:0022410; GO:0040011; GO:0051480 4814 XM_044329008.1 296 463 57 89 169 E3SCZ8 4.36e-38 Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) Cavia porcellus (Guinea pig) apoptotic process [GO:0006915]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; meiosis I [GO:0007127]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of apoptotic process [GO:0043066]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of peptidase activity [GO:0010466]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; regulation of mitotic cell cycle [GO:0007346]; regulation of type B pancreatic cell proliferation [GO:0061469]; sensory perception of sound [GO:0007605] GO:0000226; GO:0000775; GO:0000776; GO:0004869; GO:0005634; GO:0005737; GO:0005874; GO:0006915; GO:0007059; GO:0007127; GO:0007346; GO:0007605; GO:0010466; GO:0030496; GO:0043066; GO:0043524; GO:0046872; GO:0051233; GO:0051301; GO:0061178; GO:0061469 4815 XM_044313340.1 20 4 15 0 0 NA NA NA NA NA NA 4816 XM_044323606.1 0 0 0 0 12 NA NA NA NA NA NA 4817 XM_044313016.1 45 17 76 4 236 P24524 8.94e-41 Glycine receptor subunit alpha-3 Rattus norvegicus (Rat) cellular response to amino acid stimulus [GO:0071230]; cellular response to ethanol [GO:0071361]; cellular response to zinc ion [GO:0071294]; chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; neuropeptide signaling pathway [GO:0007218]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; protein homooligomerization [GO:0051260]; regulation of membrane potential [GO:0042391]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amino acid [GO:0043200]; signal transduction [GO:0007165]; synaptic transmission, glycinergic [GO:0060012] GO:0004888; GO:0005231; GO:0005886; GO:0007165; GO:0007218; GO:0007268; GO:0016594; GO:0016934; GO:0016935; GO:0022852; GO:0030425; GO:0030594; GO:0034220; GO:0042391; GO:0042734; GO:0043005; GO:0043200; GO:0043204; GO:0045202; GO:0046872; GO:0050877; GO:0051260; GO:0060012; GO:0071230; GO:0071294; GO:0071361; GO:0098690; GO:0098793; GO:0098978; GO:0098982; GO:0099171; GO:0099634; GO:1902476; GO:1904315; GO:2000300 4818 XM_044327141.1 15 14 116 0 555 B3EWZ3 0 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 4819 XM_044327141.1 15 14 116 0 555 B3EWZ3 7.42e-70 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 4820 XM_044327141.1 15 14 116 0 555 B3EWZ3 5.05e-56 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 4821 XM_044329334.1 732 620 405 858 384 NA NA NA NA NA NA 4822 XM_029333934.2 440 144 66 230 379 NA NA NA NA NA NA 4823 XM_044315070.1 95 15 8 0 49 NA NA NA NA NA NA 4824 XM_029341576.2 245 160 173 159 247 Q5U2Z0 3.18e-61 Zinc finger protein 367 Rattus norvegicus (Rat) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0003700; GO:0005634; GO:0005654; GO:0006357; GO:0046872 4825 XM_044308700.1 70 26 85 59 15 NA NA NA NA NA NA 4826 XM_029347825.2 0 7 0 0 0 D3ZZX1 2.21e-95 Inositol polyphosphate-5-phosphatase A (EC 3.1.3.56) (Type I inositol 1,4,5-trisphosphate 5-phosphatase) (5PTase) Rattus norvegicus (Rat) inositol phosphate dephosphorylation [GO:0046855]; inositol phosphate-mediated signaling [GO:0048016]; negative regulation of neuron death [GO:1901215]; phosphatidylinositol dephosphorylation [GO:0046856] GO:0004445; GO:0005886; GO:0016020; GO:0030425; GO:0042731; GO:0046855; GO:0046856; GO:0048016; GO:0052658; GO:0052659; GO:1901215 4827 XM_044316358.1 0 0 3 2 16 P42768 4.6e-31 Actin nucleation-promoting factor WAS (Wiskott-Aldrich syndrome protein) (WASp) Homo sapiens (Human) actin filament polymerization [GO:0030041]; actin filament-based movement [GO:0030048]; actin polymerization or depolymerization [GO:0008154]; blood coagulation [GO:0007596]; Cdc42 protein signal transduction [GO:0032488]; cellular response to type II interferon [GO:0071346]; defense response [GO:0006952]; endosomal transport [GO:0016197]; epidermis development [GO:0008544]; immune response [GO:0006955]; negative regulation of cell motility [GO:2000146]; negative regulation of stress fiber assembly [GO:0051497]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein-containing complex assembly [GO:0065003]; regulation of actin polymerization or depolymerization [GO:0008064]; regulation of lamellipodium assembly [GO:0010591]; regulation of stress fiber assembly [GO:0051492]; regulation of T cell antigen processing and presentation [GO:0002625]; T cell activation [GO:0042110] GO:0002625; GO:0003779; GO:0005634; GO:0005829; GO:0005884; GO:0005886; GO:0005911; GO:0006952; GO:0006955; GO:0007596; GO:0008064; GO:0008154; GO:0008544; GO:0010591; GO:0012506; GO:0015629; GO:0016197; GO:0017124; GO:0019901; GO:0030041; GO:0030048; GO:0030695; GO:0031267; GO:0032488; GO:0035861; GO:0042110; GO:0042802; GO:0043274; GO:0045335; GO:0045944; GO:0051492; GO:0051497; GO:0065003; GO:0070062; GO:0071346; GO:1905168; GO:2000146 4828 XM_029336617.2 871 625 615 1055 562 Q0VFZ6 5.59e-43 Cilia- and flagella- associated protein 210 (Coiled-coil domain-containing protein 173) Homo sapiens (Human) NA GO:0005879 4829 XM_044319820.1 178 16 28 16 157 NA NA NA NA NA NA 4830 XR_006397240.1 0 34 27 0 23 NA NA NA NA NA NA 4831 XM_044316477.1 20 10 11 17 75 NA NA NA NA NA NA 4832 XM_044319447.1 0 0 0 8 0 P40954 1.41e-22 Chitinase 3 (EC 3.2.1.14) Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) cellular bud site selection [GO:0000282]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272] GO:0000272; GO:0000282; GO:0004568; GO:0005576; GO:0006032; GO:0008061; GO:0009986 4833 XM_029341455.2 807 545 478 609 630 Q9Z2Y8 2.42e-98 Pyridoxal phosphate homeostasis protein (PLP homeostasis protein) (Proline synthase co-transcribed bacterial homolog protein) (Pyridoxal phosphate-binding protein) Mus musculus (Mouse) NA GO:0005739; GO:0005829; GO:0030170 4834 XR_006395178.1 24 6 17 60 75 A0JM24 1.54e-47 NADP-dependent oxidoreductase domain-containing protein 1 (EC 1.-.-.-) (Pyrroline-5-carboxylate reductase-like protein C14orf148 homolog) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0016491 4835 XM_029337927.2 20 0 9 0 156 NA NA NA NA NA NA 4836 XM_044323901.1 0 0 0 8 0 NA NA NA NA NA NA 4837 XM_044311483.1 0 3 10 0 0 NA NA NA NA NA NA 4838 XR_006393389.1 115 3 29 41 8 NA NA NA NA NA NA 4839 XM_029345092.2 5 0 0 13 0 NA NA NA NA NA NA 4840 XM_029337539.2 194 87 88 193 159 Q9YHV3 1.6e-33 Noggin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cartilage development [GO:0051216]; cloaca development [GO:0035844]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic viscerocranium morphogenesis [GO:0048703]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell differentiation [GO:0045596]; osteoblast differentiation [GO:0001649]; pronephros development [GO:0048793] GO:0001649; GO:0005615; GO:0007368; GO:0009953; GO:0030514; GO:0035844; GO:0045596; GO:0048703; GO:0048793; GO:0051216 4841 XM_044307479.1 9 1 6 4 44 NA NA NA NA NA NA 4842 XM_044318521.1 265 1 0 226 200 P0CI65 9.26e-52 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 4843 XM_044318521.1 265 1 0 226 200 P0CI65 1.48e-49 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 4844 XM_044318521.1 265 1 0 226 200 P0CI65 2.75e-49 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 4845 XM_044318521.1 265 1 0 226 200 P0CI65 5.59e-49 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 4846 XM_044318521.1 265 1 0 226 200 P0CI65 1.8e-46 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 4847 XM_044318521.1 265 1 0 226 200 P0CI65 1.93e-46 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 4848 XM_044318521.1 265 1 0 226 200 P0CI65 2.11e-42 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 4849 XM_044318521.1 265 1 0 226 200 P0CI65 4.2e-38 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 4850 XR_006391332.1 22 57 11 73 2 NA NA NA NA NA NA 4851 XM_044326824.1 4 1 0 0 8 NA NA NA NA NA NA 4852 XM_029347030.2 73 88 114 98 155 Q9JIF3 8.49e-98 Solute carrier family 2, facilitated glucose transporter member 8 (Glucose transporter type 8) (GLUT-8) (Glucose transporter type X1) Mus musculus (Mouse) dehydroascorbic acid transport [GO:0070837]; fructose transmembrane transport [GO:0015755]; galactose transmembrane transport [GO:0015757]; glucose metabolic process [GO:0006006]; glucose transmembrane transport [GO:1904659]; insulin receptor signaling pathway [GO:0008286]; male meiosis I [GO:0007141]; response to hypoxia [GO:0001666]; transmembrane transport [GO:0055085] GO:0001666; GO:0005353; GO:0005354; GO:0005355; GO:0005536; GO:0005886; GO:0006006; GO:0007141; GO:0008021; GO:0008286; GO:0015284; GO:0015755; GO:0015757; GO:0016020; GO:0022857; GO:0030659; GO:0033300; GO:0055085; GO:0070837; GO:1904659 4853 XM_029345996.2 453 209 269 376 439 P53804 1.13e-41 E3 ubiquitin-protein ligase TTC3 (EC 2.3.2.27) (Protein DCRR1) (RING finger protein 105) (RING-type E3 ubiquitin transferase TTC3) (TPR repeat protein D) (Tetratricopeptide repeat protein 3) (TPR repeat protein 3) Homo sapiens (Human) protein K48-linked ubiquitination [GO:0070936]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004842; GO:0005634; GO:0005654; GO:0005730; GO:0005794; GO:0005829; GO:0006511; GO:0046872; GO:0070936 4854 XM_029338459.2 76 10 0 0 0 A2VDX7 8.06e-51 Exonuclease V (Exo V) (EC 3.1.-.-) (Defects in morphology protein 1 homolog) Bos taurus (Bovine) interstrand cross-link repair [GO:0036297] GO:0003677; GO:0005634; GO:0005654; GO:0005829; GO:0036297; GO:0045145; GO:0046872; GO:0051539 4855 XM_029353502.2 0 9 0 10 0 NA NA NA NA NA NA 4856 XM_044309029.1 0 1 19 10 25 NA NA NA NA NA NA 4857 XM_044311658.1 555 1 121 124 0 B8VIU6 3.33e-72 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 4858 XM_044317375.1 98 18 0 0 18 Q7Z020 2.28e-135 Transient receptor potential cation channel subfamily A member 1 (dTRPA1) (Ankyrin-like with transmembrane domains protein 1) (dANKTM1) Drosophila melanogaster (Fruit fly) calcium ion transport [GO:0006816]; cation transport [GO:0006812]; cellular response to heat [GO:0034605]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; detection of temperature stimulus involved in thermoception [GO:0050960]; mechanosensory behavior [GO:0007638]; negative phototaxis [GO:0046957]; neuronal signal transduction [GO:0023041]; phototransduction [GO:0007602]; positive regulation of calcium-mediated signaling [GO:0050850]; response to heat [GO:0009408]; response to light stimulus [GO:0009416]; temperature compensation of the circadian clock [GO:0010378]; thermosensory behavior [GO:0040040]; thermotaxis [GO:0043052] GO:0001580; GO:0005261; GO:0005262; GO:0005886; GO:0006812; GO:0006816; GO:0007602; GO:0007638; GO:0009408; GO:0009416; GO:0010378; GO:0015276; GO:0016020; GO:0023041; GO:0034605; GO:0034703; GO:0040040; GO:0043052; GO:0046957; GO:0050850; GO:0050960; GO:0050965; GO:0050968; GO:0097604 4859 XM_044316786.1 263 240 164 440 521 Q8BTQ0 1.37e-87 Polycomb group RING finger protein 3 (RING finger protein 3A) Mus musculus (Mouse) histone H2A-K119 monoubiquitination [GO:0036353]; inactivation of X chromosome by genomic imprinting [GO:0060819]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0005634; GO:0005654; GO:0006357; GO:0031519; GO:0035102; GO:0036353; GO:0046872; GO:0060819 4860 XM_044324471.1 0 168 222 326 364 NA NA NA NA NA NA 4861 XM_029324650.2 124 167 45 102 89 NA NA NA NA NA NA 4862 XM_029336391.2 17 0 0 37 46 P16273 3.78e-36 Pathogen-related protein Hordeum vulgare (Barley) defense response [GO:0006952]; response to biotic stimulus [GO:0009607] GO:0006952; GO:0009607 4863 XR_006393098.1 13 5 0 42 14 NA NA NA NA NA NA 4864 XM_044321375.1 0 0 25 280 0 NA NA NA NA NA NA 4865 XM_044324529.1 63 0 6 10 8 Q9H892 1.78e-45 Tetratricopeptide repeat protein 12 (TPR repeat protein 12) Homo sapiens (Human) axonemal dynein complex assembly [GO:0070286]; sperm axoneme assembly [GO:0007288] GO:0005737; GO:0005813; GO:0007288; GO:0070286 4866 XM_044328758.1 0 0 123 49 0 NA NA NA NA NA NA 4867 XR_006395891.1 105 0 0 0 57 Q66IB8 1.65e-43 UPF0538 protein C2orf76 homolog Danio rerio (Zebrafish) (Brachydanio rerio) NA NA 4868 XM_029353532.2 208 284 174 257 148 NA NA NA NA NA NA 4869 XM_044308640.1 214 970 924 1643 278 NA NA NA NA NA NA 4870 XM_029354147.2 8 21 14 5 11 NA NA NA NA NA NA 4871 XM_029357440.2 159 41 117 127 73 NA NA NA NA NA NA 4872 XR_006397233.1 82 39 0 5 69 NA NA NA NA NA NA 4873 XR_006392119.1 0 54 0 0 85 NA NA NA NA NA NA 4874 XM_029357357.2 793 766 339 428 593 Q9D0F6 0 Replication factor C subunit 5 (Activator 1 36 kDa subunit) (A1 36 kDa subunit) (Activator 1 subunit 5) (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) Mus musculus (Mouse) DNA repair [GO:0006281]; DNA-templated DNA replication [GO:0006261]; positive regulation of DNA-directed DNA polymerase activity [GO:1900264] GO:0003677; GO:0003689; GO:0005524; GO:0005634; GO:0005663; GO:0006261; GO:0006281; GO:0016887; GO:0017116; GO:0019899; GO:0031390; GO:1900264 4875 XM_044324727.1 2 0 11 0 19 NA NA NA NA NA NA 4876 XM_029340483.2 5094 3860 3105 2979 3984 Q9JLB0 0 Protein PALS2 (Dlgh4 protein) (MAGUK p55 subfamily member 6) (P55T protein) (Protein associated with Lin-7 2) Mus musculus (Mouse) NA GO:0004385; GO:0005886; GO:0005911; GO:0016020 4877 XM_029338699.2 100 31 50 141 123 NA NA NA NA NA NA 4878 XR_003823179.2 54 127 94 38 80 NA NA NA NA NA NA 4879 XM_029331598.2 418 475 356 271 381 NA NA NA NA NA NA 4880 XM_044308857.1 81 72 59 88 93 NA NA NA NA NA NA 4881 XM_029344794.2 0 3 1 8 12 NA NA NA NA NA NA 4882 XM_029356216.2 50 27 6 37 33 Q804S6 2.63e-23 Homeobox protein EMX1 (Empty spiracles homolog 1) (Empty spiracles-like protein 1) Danio rerio (Zebrafish) (Brachydanio rerio) brain development [GO:0007420]; central nervous system development [GO:0007417]; neuron differentiation [GO:0030182]; pronephric distal tubule development [GO:0035777]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0007417; GO:0007420; GO:0030182; GO:0035777 4883 XM_029344462.2 416 0 416 303 0 Q8K078 4.62e-102 Solute carrier organic anion transporter family member 4A1 (Organic anion-transporting polypeptide E) (OATP-E) (Sodium-independent organic anion transporter E) (Solute carrier family 21 member 12) Mus musculus (Mouse) sodium-independent organic anion transport [GO:0043252]; thyroid hormone metabolic process [GO:0042403] GO:0005886; GO:0008514; GO:0015132; GO:0015347; GO:0015349; GO:0042403; GO:0043252 4884 XR_003824045.2 263 258 21 103 76 O31463 2.27e-51 Homocysteine S-methyltransferase YbgG (EC 2.1.1.10) (S-methylmethionine:homocysteine methyltransferase) Bacillus subtilis (strain 168) methionine biosynthetic process [GO:0009086]; methylation [GO:0032259]; S-methylmethionine cycle [GO:0033528] GO:0008270; GO:0008898; GO:0009086; GO:0032259; GO:0033528; GO:0061627 4885 XM_044315273.1 36 4 13 6 7 NA NA NA NA NA NA 4886 XM_044321634.1 51 50 84 0 34 P49914 3.46e-44 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) (5,10-methenyl-tetrahydrofolate synthetase) (MTHFS) (Methenyl-THF synthetase) Homo sapiens (Human) folic acid catabolic process [GO:0046657]; folic acid metabolic process [GO:0046655]; folic acid-containing compound biosynthetic process [GO:0009396]; formate metabolic process [GO:0015942]; glutamate metabolic process [GO:0006536]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653] GO:0005524; GO:0005542; GO:0005737; GO:0005739; GO:0005759; GO:0005829; GO:0006536; GO:0009396; GO:0015942; GO:0030272; GO:0035999; GO:0046653; GO:0046655; GO:0046657; GO:0046872 4887 XM_044317479.1 472 323 336 368 752 Q13114 1.01e-78 TNF receptor-associated factor 3 (EC 2.3.2.27) (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein 1) (LAP1) (RING-type E3 ubiquitin transferase TRAF3) Homo sapiens (Human) apoptotic process [GO:0006915]; defense response to virus [GO:0051607]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of JNK cascade [GO:0046330]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of cytokine production [GO:0001817]; regulation of defense response to virus [GO:0050688]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of interferon-beta production [GO:0032648]; regulation of proteolysis [GO:0030162]; signal transduction [GO:0007165]; Toll signaling pathway [GO:0008063]; toll-like receptor signaling pathway [GO:0002224]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; type I interferon-mediated signaling pathway [GO:0060337] GO:0000151; GO:0001817; GO:0002224; GO:0004842; GO:0005164; GO:0005739; GO:0005768; GO:0005829; GO:0006915; GO:0007165; GO:0008063; GO:0008270; GO:0009898; GO:0019901; GO:0019903; GO:0030162; GO:0031625; GO:0031996; GO:0032088; GO:0032648; GO:0033209; GO:0035631; GO:0035666; GO:0042802; GO:0042981; GO:0043122; GO:0046330; GO:0050688; GO:0051607; GO:0060337; GO:0070534; GO:1902554 4888 XM_044318095.1 11 0 0 0 0 NA NA NA NA NA NA 4889 XM_044316550.1 3837 2612 1690 4107 4478 P22607 4.62e-178 Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333) Homo sapiens (Human) bone maturation [GO:0070977]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cell-cell signaling [GO:0007267]; chondrocyte differentiation [GO:0002062]; chondrocyte proliferation [GO:0035988]; endochondral bone growth [GO:0003416]; endochondral ossification [GO:0001958]; fibroblast growth factor receptor apoptotic signaling pathway [GO:1902178]; fibroblast growth factor receptor signaling pathway [GO:0008543]; MAPK cascade [GO:0000165]; negative regulation of developmental growth [GO:0048640]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein autophosphorylation [GO:0046777]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0000165; GO:0001501; GO:0001958; GO:0002062; GO:0003416; GO:0004713; GO:0004714; GO:0005007; GO:0005524; GO:0005576; GO:0005634; GO:0005783; GO:0005794; GO:0005886; GO:0007169; GO:0007267; GO:0008284; GO:0008543; GO:0009986; GO:0010518; GO:0017134; GO:0018108; GO:0030133; GO:0030282; GO:0033674; GO:0035988; GO:0042531; GO:0042802; GO:0043235; GO:0043410; GO:0043552; GO:0046777; GO:0048640; GO:0060349; GO:0070374; GO:0070977; GO:1902178 4890 XM_044311945.1 43 1 0 43 22 NA NA NA NA NA NA 4891 XM_044327124.1 103 331 213 189 206 NA NA NA NA NA NA 4892 XM_029345230.2 44 6 10 63 17 NA NA NA NA NA NA 4893 XR_006396973.1 23 5 0 31 49 NA NA NA NA NA NA 4894 XM_029334687.2 15998 16474 8785 14919 11896 Q9U505 8.32e-25 ATP synthase lipid-binding protein, mitochondrial (ATPase protein 9) (ATPase subunit c) Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm) proton motive force-driven ATP synthesis [GO:0015986] GO:0008289; GO:0015078; GO:0015986; GO:0031966; GO:0045263 4895 XR_006394557.1 0 2 7 14 87 NA NA NA NA NA NA 4896 XM_029342180.2 2709 1415 1334 2639 2256 Q6P4L9 1.14e-153 Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0003677; GO:0031011 4897 XR_006394971.1 0 1 13 0 0 NA NA NA NA NA NA 4898 XM_029341024.2 40 147 0 60 25 O88665 3.81e-98 Bromodomain-containing protein 7 (75 kDa bromodomain protein) Mus musculus (Mouse) cell cycle [GO:0007049]; chromatin remodeling [GO:0006338]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; positive regulation of cell differentiation [GO:0045597]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of histone acetylation [GO:0035066]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of T cell differentiation [GO:0045582]; regulation of G0 to G1 transition [GO:0070316]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of nucleotide-excision repair [GO:2000819]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription initiation-coupled chromatin remodeling [GO:0045815]; Wnt signaling pathway [GO:0016055] GO:0000776; GO:0000785; GO:0000976; GO:0002039; GO:0003713; GO:0003714; GO:0005634; GO:0005654; GO:0005829; GO:0006338; GO:0006357; GO:0007049; GO:0008285; GO:0016055; GO:0016363; GO:0016586; GO:0030071; GO:0035066; GO:0042393; GO:0045582; GO:0045597; GO:0045663; GO:0045815; GO:0045892; GO:0045893; GO:0070316; GO:0070577; GO:2000045; GO:2000134; GO:2000781; GO:2000819 4899 XM_044306941.1 967 2611 2345 768 502 O18806 3.21e-36 Coagulation factor VIII (Procoagulant component) Canis lupus familiaris (Dog) (Canis familiaris) acute-phase response [GO:0006953]; blood coagulation [GO:0007596] GO:0005507; GO:0005615; GO:0006953; GO:0007596; GO:0016491 4900 XR_006394763.1 0 0 0 0 28 Q69ZM6 5.08e-180 Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog) Mus musculus (Mouse) axoneme assembly [GO:0035082]; brain development [GO:0007420]; cilium assembly [GO:0060271]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; positive regulation of hh target transcription factor activity [GO:0007228]; positive regulation of smoothened signaling pathway [GO:0045880]; post-embryonic development [GO:0009791]; protein phosphorylation [GO:0006468]; regulation of DNA-binding transcription factor activity [GO:0051090]; smoothened signaling pathway [GO:0007224] GO:0001222; GO:0003351; GO:0004674; GO:0005524; GO:0005576; GO:0005634; GO:0005737; GO:0005829; GO:0005856; GO:0006468; GO:0007224; GO:0007228; GO:0007420; GO:0009791; GO:0035082; GO:0042995; GO:0045880; GO:0046872; GO:0051090; GO:0060271; GO:0106310 4901 XM_029337501.2 387 208 135 427 275 P22570 8.93e-168 NADPH:adrenodoxin oxidoreductase, mitochondrial (AR) (Adrenodoxin reductase) (EC 1.18.1.6) (Ferredoxin--NADP(+) reductase) (Ferredoxin reductase) Homo sapiens (Human) cholesterol metabolic process [GO:0008203]; generation of precursor metabolites and energy [GO:0006091]; steroid biosynthetic process [GO:0006694]; ubiquinone biosynthetic process [GO:0006744] GO:0004324; GO:0005739; GO:0005743; GO:0005759; GO:0006091; GO:0006694; GO:0006744; GO:0008203; GO:0015039; GO:0016491 4902 XM_044312813.1 40 0 41 55 71 P55786 0 Puromycin-sensitive aminopeptidase (PSA) (EC 3.4.11.14) (Cytosol alanyl aminopeptidase) (AAP-S) Homo sapiens (Human) cellular response to hypoxia [GO:0071456]; peptide catabolic process [GO:0043171]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein polyubiquitination [GO:0000209]; proteolysis [GO:0006508] GO:0000209; GO:0004177; GO:0005634; GO:0005737; GO:0005829; GO:0006508; GO:0008270; GO:0042277; GO:0043171; GO:0070006; GO:0070062; GO:0071456; GO:1903955 4903 XM_029351046.2 247 308 91 41 210 E7FAM5 3.09e-54 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 4904 XM_029323571.2 834 566 658 541 846 O75131 0 Copine-3 (Copine III) Homo sapiens (Human) cellular response to calcium ion [GO:0071277]; cellular response to growth factor stimulus [GO:0071363]; ERBB2 signaling pathway [GO:0038128]; positive regulation of cell migration [GO:0030335] GO:0003723; GO:0004674; GO:0005544; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005739; GO:0005829; GO:0005886; GO:0005925; GO:0030054; GO:0030335; GO:0030971; GO:0035577; GO:0038128; GO:0046872; GO:0048306; GO:0070062; GO:0071277; GO:0071363 4905 XM_029339165.2 73 59 60 108 95 Q7T3A4 4.41e-27 Ras-related protein Rab-13 Danio rerio (Zebrafish) (Brachydanio rerio) angiogenesis [GO:0001525]; bicellular tight junction assembly [GO:0070830]; cellular response to insulin stimulus [GO:0032869]; cortical actin cytoskeleton organization [GO:0030866]; endocytic recycling [GO:0032456]; endothelial cell chemotaxis [GO:0035767]; Golgi vesicle fusion to target membrane [GO:0048210]; neuron projection development [GO:0031175]; protein kinase A signaling [GO:0010737]; protein localization to cell leading edge [GO:1902463]; protein localization to plasma membrane [GO:0072659]; protein secretion [GO:0009306]; regulation of exocytosis [GO:0017157]; trans-Golgi network to recycling endosome transport [GO:0044795]; vesicle docking involved in exocytosis [GO:0006904] GO:0001525; GO:0003924; GO:0005525; GO:0005768; GO:0005802; GO:0005886; GO:0005923; GO:0006904; GO:0008021; GO:0009306; GO:0010737; GO:0016328; GO:0017157; GO:0030027; GO:0030139; GO:0030140; GO:0030866; GO:0031175; GO:0031410; GO:0032456; GO:0032593; GO:0032869; GO:0035767; GO:0043005; GO:0043231; GO:0044795; GO:0048210; GO:0055037; GO:0055038; GO:0070830; GO:0072659; GO:1902463 4906 XM_044318262.1 0 0 0 24 0 P31422 0 Metabotropic glutamate receptor 3 (mGluR3) Rattus norvegicus (Rat) G protein-coupled glutamate receptor signaling pathway [GO:0007216]; gene expression [GO:0010467]; modulation of chemical synaptic transmission [GO:0050804]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; regulation of synaptic transmission, glutamatergic [GO:0051966]; sensory perception of pain [GO:0019233] GO:0001640; GO:0001641; GO:0005246; GO:0005886; GO:0007216; GO:0010467; GO:0014069; GO:0019233; GO:0030424; GO:0042734; GO:0043005; GO:0043197; GO:0045211; GO:0050804; GO:0051966; GO:0097110; GO:0097449; GO:0098794; GO:0098978; GO:0099170 4907 XR_006395952.1 71 93 26 40 47 NA NA NA NA NA NA 4908 XM_044325889.1 2005 904 1633 4042 1745 P48506 0 Glutamate--cysteine ligase catalytic subunit (EC 6.3.2.2) (GCS heavy chain) (Gamma-ECS) (Gamma-glutamylcysteine synthetase) Homo sapiens (Human) aging [GO:0007568]; blood vessel diameter maintenance [GO:0097746]; cell redox homeostasis [GO:0045454]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to glucose stimulus [GO:0071333]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to insulin stimulus [GO:0032869]; cellular response to mechanical stimulus [GO:0071260]; cellular response to thyroxine stimulus [GO:0097069]; cysteine metabolic process [GO:0006534]; glutamate metabolic process [GO:0006536]; glutathione biosynthetic process [GO:0006750]; L-ascorbic acid metabolic process [GO:0019852]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of hepatic stellate cell activation [GO:2000490]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; regulation of mitochondrial depolarization [GO:0051900]; response to activity [GO:0014823]; response to arsenic-containing substance [GO:0046685]; response to cadmium ion [GO:0046686]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to human chorionic gonadotropin [GO:0044752]; response to interleukin-1 [GO:0070555]; response to nitrosative stress [GO:0051409]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to xenobiotic stimulus [GO:0009410] GO:0000287; GO:0004357; GO:0005524; GO:0005739; GO:0005829; GO:0006534; GO:0006536; GO:0006750; GO:0006979; GO:0007568; GO:0007584; GO:0009408; GO:0009410; GO:0009725; GO:0014823; GO:0016595; GO:0017109; GO:0019852; GO:0031397; GO:0032436; GO:0032869; GO:0035729; GO:0043066; GO:0043524; GO:0043531; GO:0044344; GO:0044752; GO:0044877; GO:0045454; GO:0045892; GO:0046685; GO:0046686; GO:0051409; GO:0051900; GO:0070555; GO:0071260; GO:0071333; GO:0071372; GO:0097069; GO:0097746; GO:1901029; GO:2000490; GO:2001237 4909 XM_029346087.2 0 10 0 0 0 Q3MIT2 6.86e-112 tRNA pseudouridine synthase Pus10 (Hup10) (EC 5.4.99.25) (Coiled-coil domain-containing protein 139) (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA pseudouridylate synthase) (tRNA-uridine isomerase) Homo sapiens (Human) primary miRNA processing [GO:0031053]; tRNA pseudouridine synthesis [GO:0031119] GO:0005634; GO:0005737; GO:0005739; GO:0009982; GO:0031053; GO:0031119; GO:0046872; GO:0070878; GO:0106029 4910 XM_029323996.2 3772 2702 2214 3305 1826 NA NA NA NA NA NA 4911 XM_029341290.2 566 299 254 426 464 Q6ZNE5 2.23e-57 Beclin 1-associated autophagy-related key regulator (Barkor) (Autophagy-related protein 14-like protein) (Atg14L) Homo sapiens (Human) autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagosome membrane docking [GO:0016240]; cellular response to glucose starvation [GO:0042149]; cellular response to starvation [GO:0009267]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; macroautophagy [GO:0016236]; mitophagy [GO:0000423]; negative regulation of protein phosphorylation [GO:0001933]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein phosphorylation [GO:0001934]; post-transcriptional regulation of gene expression [GO:0010608]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; regulation of macroautophagy [GO:0016241]; regulation of protein complex stability [GO:0061635]; regulation of protein phosphorylation [GO:0001932]; regulation of triglyceride metabolic process [GO:0090207]; response to mitochondrial depolarisation [GO:0098780] GO:0000045; GO:0000421; GO:0000423; GO:0001932; GO:0001933; GO:0001934; GO:0005776; GO:0005789; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0008333; GO:0009267; GO:0010608; GO:0016236; GO:0016240; GO:0016241; GO:0034045; GO:0035032; GO:0036092; GO:0042149; GO:0043552; GO:0044233; GO:0045022; GO:0045335; GO:0051020; GO:0061635; GO:0090207; GO:0097352; GO:0097629; GO:0097632; GO:0098780 4912 XM_044307969.1 447 565 200 830 16 Q29599 3.23e-34 2'-5'-oligoadenylate synthase 1 ((2-5')oligo(A) synthase 1) (2-5A synthase 1) (EC 2.7.7.84) (p42 OAS) Sus scrofa (Pig) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; regulation of ribonuclease activity [GO:0060700] GO:0001730; GO:0003725; GO:0005524; GO:0005576; GO:0005654; GO:0005737; GO:0005739; GO:0005783; GO:0005829; GO:0016020; GO:0045071; GO:0045087; GO:0046872; GO:0051607; GO:0060700 4913 XM_029330341.2 0 0 0 0 13 Q924A2 1.72e-40 Protein capicua homolog Mus musculus (Mouse) brain development [GO:0007420]; learning [GO:0007612]; lung alveolus development [GO:0048286]; memory [GO:0007613]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357]; social behavior [GO:0035176]; transcription by RNA polymerase II [GO:0006366] GO:0000122; GO:0000977; GO:0000981; GO:0003682; GO:0005634; GO:0005654; GO:0006357; GO:0006366; GO:0007420; GO:0007612; GO:0007613; GO:0032991; GO:0035176; GO:0043231; GO:0045892; GO:0048286 4914 XM_029330341.2 0 0 0 0 13 Q924A2 2.15e-21 Protein capicua homolog Mus musculus (Mouse) brain development [GO:0007420]; learning [GO:0007612]; lung alveolus development [GO:0048286]; memory [GO:0007613]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357]; social behavior [GO:0035176]; transcription by RNA polymerase II [GO:0006366] GO:0000122; GO:0000977; GO:0000981; GO:0003682; GO:0005634; GO:0005654; GO:0006357; GO:0006366; GO:0007420; GO:0007612; GO:0007613; GO:0032991; GO:0035176; GO:0043231; GO:0045892; GO:0048286 4915 XM_044315491.1 5 0 6 5 0 NA NA NA NA NA NA 4916 XM_044321322.1 23 9 42 40 96 P46023 6.43e-100 G-protein coupled receptor GRL101 Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004930; GO:0005886 4917 XM_029336544.2 1562 1252 843 1564 1505 Q5U430 0 E3 ubiquitin-protein ligase UBR3 (EC 2.3.2.27) (N-recognin-3) (RING-type E3 ubiquitin transferase UBR3) (Ubiquitin-protein ligase E3-alpha-3) (Ubiquitin-protein ligase E3-alpha-III) (Zinc finger protein 650) Mus musculus (Mouse) embryo development ending in birth or egg hatching [GO:0009792]; in utero embryonic development [GO:0001701]; negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel [GO:1904878]; olfactory behavior [GO:0042048]; positive regulation of protein catabolic process [GO:0045732]; protein ubiquitination [GO:0016567]; sensory perception of smell [GO:0007608]; suckling behavior [GO:0001967]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent protein catabolic process via the N-end rule pathway [GO:0071596] GO:0000151; GO:0001701; GO:0001967; GO:0004842; GO:0005737; GO:0006511; GO:0007608; GO:0008270; GO:0009792; GO:0016020; GO:0016567; GO:0042048; GO:0045732; GO:0061630; GO:0071596; GO:1904878 4918 XM_029336544.2 1562 1252 843 1564 1505 Q5U430 2.87e-114 E3 ubiquitin-protein ligase UBR3 (EC 2.3.2.27) (N-recognin-3) (RING-type E3 ubiquitin transferase UBR3) (Ubiquitin-protein ligase E3-alpha-3) (Ubiquitin-protein ligase E3-alpha-III) (Zinc finger protein 650) Mus musculus (Mouse) embryo development ending in birth or egg hatching [GO:0009792]; in utero embryonic development [GO:0001701]; negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel [GO:1904878]; olfactory behavior [GO:0042048]; positive regulation of protein catabolic process [GO:0045732]; protein ubiquitination [GO:0016567]; sensory perception of smell [GO:0007608]; suckling behavior [GO:0001967]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent protein catabolic process via the N-end rule pathway [GO:0071596] GO:0000151; GO:0001701; GO:0001967; GO:0004842; GO:0005737; GO:0006511; GO:0007608; GO:0008270; GO:0009792; GO:0016020; GO:0016567; GO:0042048; GO:0045732; GO:0061630; GO:0071596; GO:1904878 4919 XR_006395761.1 0 0 0 0 7 NA NA NA NA NA NA 4920 XM_029355992.2 0 0 0 0 16 NA NA NA NA NA NA 4921 XM_044323549.1 55 2 36 9 67 NA NA NA NA NA NA 4922 XM_029357391.2 31 70 27 46 44 Q9NXW9 3.28e-77 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 (Alkylated DNA repair protein alkB homolog 4) (DNA N6-methyl adenine demethylase ALKBH4) (EC 1.14.11.51) (Lysine-specific demethylase ALKBH4) (EC 1.14.11.-) Homo sapiens (Human) actomyosin structure organization [GO:0031032]; chromatin organization [GO:0006325]; cleavage furrow ingression [GO:0036090]; DNA demethylation [GO:0080111]; oxidative demethylation [GO:0070989]; protein demethylation [GO:0006482]; regulation of chromatin organization [GO:1902275] GO:0003779; GO:0005730; GO:0005737; GO:0006325; GO:0006482; GO:0016491; GO:0016706; GO:0030496; GO:0031032; GO:0032451; GO:0035516; GO:0036090; GO:0046872; GO:0070938; GO:0070989; GO:0080111; GO:1902275 4923 XM_029329445.2 168 108 198 218 325 O94818 4.25e-35 Nucleolar protein 4 (Nucleolar-localized protein) Homo sapiens (Human) NA GO:0003723; GO:0005730 4924 XM_029329445.2 168 108 198 218 325 O94818 3.38e-27 Nucleolar protein 4 (Nucleolar-localized protein) Homo sapiens (Human) NA GO:0003723; GO:0005730 4925 XM_044317323.1 260 401 99 254 0 Q86AW9 6.71e-143 Guanine deaminase (Guanase) (Guanine aminase) (EC 3.5.4.3) (Guanine aminohydrolase) (GAH) Dictyostelium discoideum (Social amoeba) guanine catabolic process [GO:0006147]; guanine metabolic process [GO:0046098] GO:0005829; GO:0006147; GO:0008270; GO:0008892; GO:0019239; GO:0046098 4926 XM_044317781.1 112 41 92 199 88 Q9D2Z8 4.02e-101 Kinesin-like protein KIF12 Mus musculus (Mouse) microtubule-based movement [GO:0007018] GO:0003777; GO:0005524; GO:0005737; GO:0005815; GO:0005871; GO:0005874; GO:0007018; GO:0008017; GO:0016887; GO:0070062 4927 XM_044324390.1 20 6 61 28 63 NA NA NA NA NA NA 4928 XM_029351568.2 1240 845 481 744 717 NA NA NA NA NA NA 4929 XM_044308036.1 100 123 59 719 21 B3EWZ3 4.88e-93 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 4930 XM_044308036.1 100 123 59 719 21 B3EWZ3 1.76e-85 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 4931 XM_044308036.1 100 123 59 719 21 B3EWZ3 1.91e-68 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 4932 XM_044308036.1 100 123 59 719 21 B3EWZ3 1.17e-67 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 4933 XM_044308036.1 100 123 59 719 21 B3EWZ3 6.19e-66 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 4934 XM_044308036.1 100 123 59 719 21 B3EWZ3 6.99e-54 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 4935 XM_029329632.2 264 281 166 103 170 NA NA NA NA NA NA 4936 XM_044325509.1 18 0 0 32 0 NA NA NA NA NA NA 4937 XM_044309114.1 115 0 0 235 10 NA NA NA NA NA NA 4938 XM_029342988.2 785 509 571 949 829 Q9JID6 0 Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3) (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain acyl-CoA synthetase 1) (LACS 1) (Palmitoyl-CoA ligase) (Phytanate--CoA ligase) (EC 6.2.1.24) Cavia porcellus (Guinea pig) long-chain fatty acid metabolic process [GO:0001676]; very long-chain fatty acid metabolic process [GO:0000038] GO:0000038; GO:0001676; GO:0004467; GO:0005524; GO:0005741; GO:0005778; GO:0005783; GO:0005789; GO:0047676; GO:0050197; GO:0070251 4939 XM_029338973.2 324 274 106 291 381 NA NA NA NA NA NA 4940 XM_029337275.2 1098 747 621 1080 461 A6NFN3 3.38e-36 RNA binding protein fox-1 homolog 3 (Fox-1 homolog C) (Neuronal nuclei antigen) (NeuN antigen) Homo sapiens (Human) mRNA processing [GO:0006397]; nervous system development [GO:0007399]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380] GO:0000381; GO:0003729; GO:0005634; GO:0005737; GO:0006397; GO:0007399; GO:0008380 4941 XR_006395822.1 167 132 73 150 87 NA NA NA NA NA NA 4942 XR_006398144.1 1595 35 37 32 138 NA NA NA NA NA NA 4943 XM_044309529.1 694 388 401 633 470 Q6ZWL3 7.71e-143 Cytochrome P450 4V2 (Docosahexaenoic acid omega-hydroxylase CYP4V2) (EC 1.14.14.79) (Long-chain fatty acid omega-monooxygenase) (EC 1.14.14.80) Homo sapiens (Human) fatty acid omega-oxidation [GO:0010430]; response to stimulus [GO:0050896]; retinoid metabolic process [GO:0001523]; sterol metabolic process [GO:0016125]; visual perception [GO:0007601] GO:0001523; GO:0004497; GO:0005506; GO:0005789; GO:0007601; GO:0010430; GO:0016125; GO:0020037; GO:0050896; GO:0102033 4944 XM_029345897.2 87 0 109 343 138 Q059U7 3.58e-158 Protein inturned (Inturned planar cell polarity effector homolog) (PDZ domain-containing protein 6) Mus musculus (Mouse) cell division [GO:0051301]; cilium assembly [GO:0060271]; embryonic digit morphogenesis [GO:0042733]; establishment of planar polarity [GO:0001736]; hair follicle morphogenesis [GO:0031069]; intraciliary transport [GO:0042073]; keratinocyte differentiation [GO:0030216]; limb development [GO:0060173]; motile cilium assembly [GO:0044458]; negative regulation of cell division [GO:0051782]; negative regulation of keratinocyte proliferation [GO:0010839]; nervous system development [GO:0007399]; neural tube development [GO:0021915]; non-motile cilium assembly [GO:1905515]; positive regulation of smoothened signaling pathway [GO:0045880]; protein localization to organelle [GO:0033365]; regulation of cilium assembly [GO:1902017]; regulation of ossification [GO:0030278]; regulation of smoothened signaling pathway [GO:0008589]; roof of mouth development [GO:0060021]; smoothened signaling pathway [GO:0007224]; spinal cord dorsal/ventral patterning [GO:0021513]; tongue morphogenesis [GO:0043587]; vesicle-mediated transport [GO:0016192] GO:0001736; GO:0005737; GO:0005814; GO:0005929; GO:0007224; GO:0007399; GO:0008589; GO:0009986; GO:0010839; GO:0016192; GO:0021513; GO:0021915; GO:0030216; GO:0030278; GO:0031069; GO:0031514; GO:0033365; GO:0035869; GO:0036064; GO:0042073; GO:0042733; GO:0043587; GO:0044458; GO:0045880; GO:0051301; GO:0051782; GO:0060021; GO:0060173; GO:0060271; GO:1902017; GO:1905515 4945 XR_003825789.2 0 0 7 1 6 NA NA NA NA NA NA 4946 XM_029345273.2 11 7 0 13 4 NA NA NA NA NA NA 4947 XM_044309500.1 0 0 0 0 6 NA NA NA NA NA NA 4948 XM_044329121.1 492 516 382 420 330 Q8BHR8 2.71e-94 Centriolar satellite-associated tubulin polyglutamylase complex regulator 1 Mus musculus (Mouse) NA GO:0005737; GO:0005874; GO:0034451 4949 XM_029342473.2 542 341 247 558 704 O54992 3.94e-130 MAP kinase-activated protein kinase 5 (MAPK-activated protein kinase 5) (MAPKAP kinase 5) (MAPKAPK-5) (EC 2.7.11.1) Mus musculus (Mouse) intracellular signal transduction [GO:0035556]; negative regulation of TOR signaling [GO:0032007]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein autophosphorylation [GO:0046777]; Ras protein signal transduction [GO:0007265]; regulation of translation [GO:0006417]; stress-induced premature senescence [GO:0090400] GO:0002039; GO:0004672; GO:0004674; GO:0004683; GO:0005516; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006417; GO:0007265; GO:0009931; GO:0018105; GO:0032007; GO:0032156; GO:0032212; GO:0032991; GO:0035556; GO:0046777; GO:0051019; GO:0051973; GO:0060999; GO:0090400; GO:0106310; GO:1904355 4950 XR_006392997.1 41 2 25 5 151 NA NA NA NA NA NA 4951 XM_029347437.2 9 0 0 0 19 NA NA NA NA NA NA 4952 XM_029354599.2 4882 5051 4270 7094 6776 Q15723 3.78e-32 ETS-related transcription factor Elf-2 (E74-like factor 2) (New ETS-related factor) Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000785; GO:0000981; GO:0003700; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0016604; GO:0030154; GO:0043565; GO:0045892; GO:0045893; GO:1990837 4953 XM_044329336.1 296 619 1974 6453 3103 P58027 4.31e-145 Amine oxidase [flavin-containing] A (EC 1.4.3.21) (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A) Canis lupus familiaris (Dog) (Canis familiaris) catecholamine metabolic process [GO:0006584]; neurotransmitter catabolic process [GO:0042135] GO:0005739; GO:0005741; GO:0006584; GO:0008131; GO:0042135; GO:0050660; GO:0052595; GO:0052596; GO:0097621 4954 XM_044309479.1 6 19 10 22 15 NA NA NA NA NA NA 4955 XM_029342776.2 0 0 33 0 0 NA NA NA NA NA NA 4956 XM_029330328.2 512 111 432 357 353 O43933 0 Peroxisomal ATPase PEX1 (EC 3.6.4.-) (Peroxin-1) (Peroxisome biogenesis disorder protein 1) (Peroxisome biogenesis factor 1) Homo sapiens (Human) microtubule-based peroxisome localization [GO:0060152]; peroxisome organization [GO:0007031]; protein import into peroxisome matrix [GO:0016558]; protein import into peroxisome matrix, receptor recycling [GO:0016562]; protein targeting to peroxisome [GO:0006625]; protein unfolding [GO:0043335] GO:0005524; GO:0005737; GO:0005777; GO:0005778; GO:0005829; GO:0006625; GO:0007031; GO:0008022; GO:0016558; GO:0016562; GO:0016887; GO:0043335; GO:0044877; GO:0060152; GO:0070062; GO:0140036; GO:0140318 4957 XM_044321197.1 63 22 233 40 182 A3KNS9 5.03e-22 All-trans retinoic acid-induced differentiation factor (Apoptosis-related protein 3) (APR-3) Danio rerio (Zebrafish) (Brachydanio rerio) anatomical structure development [GO:0048856]; cell differentiation [GO:0030154]; negative regulation of osteoblast proliferation [GO:0033689]; negative regulation of protein catabolic process [GO:0042177]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of gene expression [GO:0010468] GO:0005635; GO:0005886; GO:0010468; GO:0030154; GO:0030501; GO:0033689; GO:0042177; GO:0043231; GO:0045669; GO:0048471; GO:0048856 4958 XM_029351364.2 1773 1238 863 1140 902 Q0IH24 1.78e-39 Sperm flagellar protein 1 Xenopus laevis (African clawed frog) axonemal central apparatus assembly [GO:1904158]; cell migration [GO:0016477]; cilium movement [GO:0003341]; filopodium assembly [GO:0046847]; lamellipodium assembly [GO:0030032]; microtubule bundle formation [GO:0001578]; negative regulation of cell death [GO:0060548]; negative regulation of microtubule depolymerization [GO:0007026]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095] GO:0001578; GO:0003341; GO:0005874; GO:0005902; GO:0005930; GO:0007026; GO:0008017; GO:0016323; GO:0016324; GO:0016477; GO:0030027; GO:0030032; GO:0030175; GO:0046847; GO:0060548; GO:0097542; GO:0097729; GO:1904158; GO:1990716; GO:2000095 4959 XM_029338685.2 48 29 81 55 253 O75414 5.07e-35 Nucleoside diphosphate kinase 6 (NDK 6) (NDP kinase 6) (EC 2.7.4.6) (Inhibitor of p53-induced apoptosis-alpha) (IPIA-alpha) (nm23-H6) Homo sapiens (Human) apoptotic process [GO:0006915]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; negative regulation of cell growth [GO:0030308]; negative regulation of mitotic nuclear division [GO:0045839]; nucleoside diphosphate phosphorylation [GO:0006165]; UTP biosynthetic process [GO:0006228] GO:0004550; GO:0005524; GO:0005739; GO:0006165; GO:0006183; GO:0006228; GO:0006241; GO:0006915; GO:0030308; GO:0045839; GO:0046872 4960 XM_044307344.1 0 0 0 0 7 NA NA NA NA NA NA 4961 XM_029348969.2 0 61 0 71 0 F1R8P4 1.58e-94 Glycine receptor subunit alpha-2 Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0004888; GO:0005254; GO:0016594; GO:0016933; GO:0022824; GO:0034707; GO:0042995; GO:0045211; GO:0046872 4962 XM_044323949.1 146 91 55 60 81 B8VIU6 1.77e-39 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 4963 XM_029346244.2 260 314 111 237 84 NA NA NA NA NA NA 4964 XM_029355582.2 342 85 391 192 379 Q5ZIJ9 5.2e-50 E3 ubiquitin-protein ligase MIB2 (EC 2.3.2.27) (Mind bomb homolog 2) (RING-type E3 ubiquitin transferase MIB2) Gallus gallus (Chicken) Notch signaling pathway [GO:0007219]; protein ubiquitination [GO:0016567] GO:0004842; GO:0005737; GO:0007219; GO:0008270; GO:0016567 4965 XM_029351984.2 1 3 50 5 13 P18907 0 Sodium/potassium-transporting ATPase subunit alpha-1 (Sodium pump subunit alpha-1) (EC 7.2.2.13) (Na(+)/K(+) ATPase alpha-1 subunit) Equus caballus (Horse) cellular potassium ion homeostasis [GO:0030007]; cellular sodium ion homeostasis [GO:0006883]; potassium ion import across plasma membrane [GO:1990573]; proton transmembrane transport [GO:1902600]; regulation of sodium ion transport [GO:0002028]; sodium ion export across plasma membrane [GO:0036376] GO:0002028; GO:0005391; GO:0005524; GO:0005886; GO:0005890; GO:0006883; GO:0016020; GO:0016323; GO:0016887; GO:0019829; GO:0030007; GO:0030424; GO:0036376; GO:0042383; GO:0042470; GO:0046872; GO:1902600; GO:1990573 4966 XM_044321930.1 0 0 6 0 4 NA NA NA NA NA NA 4967 XM_044320134.1 20 4 31 2 93 NA NA NA NA NA NA 4968 XM_029352116.2 676 299 268 464 536 A6H603 1.78e-100 NACHT domain- and WD repeat-containing protein 1 Mus musculus (Mouse) negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of gene expression [GO:0010628] GO:0005524; GO:0005730; GO:0005829; GO:0010628; GO:0032088 4969 XM_029353161.2 456 220 210 315 478 Q9NQW7 0 Xaa-Pro aminopeptidase 1 (EC 3.4.11.9) (Aminoacylproline aminopeptidase) (Cytosolic aminopeptidase P) (Soluble aminopeptidase P) (sAmp) (X-Pro aminopeptidase 1) (X-prolyl aminopeptidase 1, soluble) Homo sapiens (Human) bradykinin catabolic process [GO:0010815]; proteolysis [GO:0006508] GO:0004177; GO:0005737; GO:0005829; GO:0006508; GO:0010815; GO:0030145; GO:0042803; GO:0070006; GO:0070062 4970 XM_044319046.1 69 0 0 41 137 Q9H0Z9 1.63e-31 RNA-binding protein 38 (CLL-associated antigen KW-5) (HSRNASEB) (RNA-binding motif protein 38) (RNA-binding region-containing protein 1) (ssDNA-binding protein SEB4) Homo sapiens (Human) 3'-UTR-mediated mRNA stabilization [GO:0070935]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; mRNA processing [GO:0006397]; mRNA stabilization [GO:0048255]; negative regulation of cell population proliferation [GO:0008285]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of cell cycle [GO:0051726]; regulation of myotube differentiation [GO:0010830]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380] GO:0000381; GO:0003723; GO:0003729; GO:0003730; GO:0005634; GO:0005829; GO:0006397; GO:0006977; GO:0006978; GO:0007049; GO:0008285; GO:0008380; GO:0010830; GO:0030154; GO:0043484; GO:0048255; GO:0051726; GO:0070935 4971 XM_029358369.2 1596 965 798 1774 1124 G1T7U7 1.08e-95 N-acylethanolamine-hydrolyzing acid amidase (EC 3.5.1.60) (Acylsphingosine deacylase NAAA) (EC 3.5.1.23) [Cleaved into: N-acylethanolamine-hydrolyzing acid amidase subunit alpha; N-acylethanolamine-hydrolyzing acid amidase subunit beta] Oryctolagus cuniculus (Rabbit) fatty acid metabolic process [GO:0006631]; lipid catabolic process [GO:0016042]; N-acylethanolamine metabolic process [GO:0070291]; N-acylphosphatidylethanolamine metabolic process [GO:0070292]; sphingosine metabolic process [GO:0006670] GO:0005764; GO:0006631; GO:0006670; GO:0016042; GO:0017040; GO:0017064; GO:0019898; GO:0047412; GO:0070291; GO:0070292; GO:0102121 4972 XM_044325514.1 581 221 265 496 648 Q149N8 0 E3 ubiquitin-protein ligase SHPRH (EC 2.3.2.27) (EC 3.6.4.-) (RING-type E3 ubiquitin transferase SHPRH) (SNF2, histone-linker, PHD and RING finger domain-containing helicase) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; nucleosome assembly [GO:0006334]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567] GO:0000209; GO:0000786; GO:0003677; GO:0004386; GO:0004842; GO:0005524; GO:0005654; GO:0006281; GO:0006334; GO:0006974; GO:0016567; GO:0016787; GO:0031625; GO:0046872; GO:0061630; GO:0140658 4973 XM_044309516.1 1 11 2 40 12 NA NA NA NA NA NA 4974 XM_029355882.2 95 77 80 103 87 NA NA NA NA NA NA 4975 XM_044322573.1 0 3 1 0 22 NA NA NA NA NA NA 4976 XM_044307126.1 1 1 137 172 9 Q9U6Y6 5.65e-108 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 4977 XM_044311400.1 25 1 13 42 36 Q7LHG5 9.6e-73 Transposon Ty3-I Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-2 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p52 (IN); Integrase p49 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 4978 XM_044311400.1 25 1 13 42 36 Q7LHG5 9.6e-73 Transposon Ty3-I Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-2 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p52 (IN); Integrase p49 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 4979 XM_029358711.2 669 535 441 547 722 Q6GR45 7.92e-148 Eukaryotic translation initiation factor 6 (eIF-6) Xenopus laevis (African clawed frog) cytosolic ribosome assembly [GO:0042256]; ribosomal large subunit biogenesis [GO:0042273] GO:0003743; GO:0005730; GO:0005737; GO:0042256; GO:0042273; GO:0043022; GO:0043023 4980 XM_044319637.1 0 70 0 0 0 O94762 5.62e-163 ATP-dependent DNA helicase Q5 (EC 3.6.4.12) (DNA helicase, RecQ-like type 5) (RecQ5) (RecQ protein-like 5) Homo sapiens (Human) cell division [GO:0051301]; cellular response to camptothecin [GO:0072757]; cellular response to ketone [GO:1901655]; cellular response to xenobiotic stimulus [GO:0071466]; chromosome separation [GO:0051304]; DNA duplex unwinding [GO:0032508]; DNA metabolic process [GO:0006259]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724]; mitotic cell cycle [GO:0000278]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; negative regulation of transcription elongation by RNA polymerase II [GO:0034244]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414] GO:0000278; GO:0000724; GO:0000993; GO:0003676; GO:0003678; GO:0005524; GO:0005634; GO:0005654; GO:0005694; GO:0005737; GO:0005829; GO:0006259; GO:0006260; GO:0006268; GO:0006281; GO:0006310; GO:0009378; GO:0016591; GO:0016887; GO:0032508; GO:0034244; GO:0042802; GO:0043138; GO:0051301; GO:0051304; GO:0071466; GO:0072757; GO:1901655; GO:1990414; GO:2000042 4981 XM_044321060.1 19 0 0 0 1 NA NA NA NA NA NA 4982 XM_029335280.2 322 222 144 222 215 Q9Y5B0 7.69e-81 RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase) Homo sapiens (Human) cell division [GO:0051301]; dephosphorylation of RNA polymerase II C-terminal domain [GO:0070940]; exit from mitosis [GO:0010458]; negative regulation of cell growth involved in cardiac muscle cell development [GO:0061052]; positive regulation by host of viral transcription [GO:0043923]; protein dephosphorylation [GO:0006470]; transcription elongation by RNA polymerase II promoter [GO:0006368] GO:0000922; GO:0001096; GO:0004721; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0005819; GO:0006368; GO:0006470; GO:0008420; GO:0010458; GO:0017018; GO:0030496; GO:0030957; GO:0032991; GO:0043231; GO:0043923; GO:0051233; GO:0051301; GO:0061052; GO:0070940 4983 XM_044319276.1 21 27 9 172 9 Q8K3Z0 1.28e-29 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 4984 XM_044313219.1 3 35 0 14 0 Q866A2 3.6e-49 Neuronal acetylcholine receptor subunit alpha-7 Macaca mulatta (Rhesus macaque) associative learning [GO:0008306]; B cell activation [GO:0042113]; behavioral response to ethanol [GO:0048149]; behavioral response to nicotine [GO:0035095]; calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; cognition [GO:0050890]; dendrite arborization [GO:0140059]; dendritic spine organization [GO:0097061]; endocytosis [GO:0006897]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; generation of ovulation cycle rhythm [GO:0060112]; ion transmembrane transport [GO:0034220]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of tumor necrosis factor production [GO:0032720]; nervous system process [GO:0050877]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of CoA-transferase activity [GO:1905920]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure [GO:0001988]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; regulation of amyloid fibril formation [GO:1905906]; regulation of membrane potential [GO:0042391]; regulation of neuron death [GO:1901214]; regulation of norepinephrine secretion [GO:0014061]; regulation of synaptic transmission, dopaminergic [GO:0032225]; response to amyloid-beta [GO:1904645]; response to cold [GO:0009409]; response to food [GO:0032094]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; sensory processing [GO:0050893]; short-term memory [GO:0007614]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271]; T cell activation [GO:0042110] GO:0001540; GO:0001666; GO:0001933; GO:0001988; GO:0005231; GO:0005886; GO:0005892; GO:0006816; GO:0006874; GO:0006897; GO:0007165; GO:0007268; GO:0007271; GO:0007614; GO:0008284; GO:0008306; GO:0009409; GO:0009897; GO:0014061; GO:0015464; GO:0015643; GO:0016324; GO:0017081; GO:0022848; GO:0030317; GO:0030594; GO:0030673; GO:0032094; GO:0032225; GO:0032691; GO:0032715; GO:0032720; GO:0033138; GO:0034220; GO:0035094; GO:0035095; GO:0042110; GO:0042113; GO:0042166; GO:0042391; GO:0042734; GO:0042803; GO:0043005; GO:0043410; GO:0045202; GO:0045766; GO:0048149; GO:0050728; GO:0050877; GO:0050890; GO:0050893; GO:0051649; GO:0060112; GO:0070374; GO:0097061; GO:0098839; GO:0098978; GO:0098981; GO:0140059; GO:1900273; GO:1901214; GO:1902004; GO:1904315; GO:1904645; GO:1905906; GO:1905920; GO:2000463 4985 XR_003824965.2 30 29 35 21 36 NA NA NA NA NA NA 4986 XR_006392421.1 0 5 0 29 27 NA NA NA NA NA NA 4987 XM_029344284.2 1080 1281 801 1256 956 NA NA NA NA NA NA 4988 XM_044307259.1 226 163 160 458 362 Q642T7 9.91e-144 U3 small nucleolar RNA-associated protein 25 homolog (Digestive organ expansion factor homolog) (UTP25 small subunit processor component) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) digestive tract morphogenesis [GO:0048546]; embryonic organ development [GO:0048568]; exocrine pancreas development [GO:0031017]; inflammatory response to wounding [GO:0090594]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; organ growth [GO:0035265]; protein catabolic process [GO:0030163]; protein destabilization [GO:0031648]; protein localization to nucleolus [GO:1902570]; sympathetic nervous system development [GO:0048485] GO:0000462; GO:0005730; GO:0030163; GO:0031017; GO:0031648; GO:0034511; GO:0035265; GO:0048485; GO:0048546; GO:0048568; GO:0090594; GO:1902570 4989 XM_029334029.2 124 77 158 171 245 NA NA NA NA NA NA 4990 XM_044314779.1 0 3 7 23 5 Q09575 4.61e-27 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 4991 XM_044314779.1 0 3 7 23 5 Q09575 4.61e-27 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 4992 XM_029353580.2 22 3 2 9 29 NA NA NA NA NA NA 4993 XM_044323979.1 3 0 0 0 7 O95263 0 High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B (HsPDE8B) (EC 3.1.4.53) (Cell proliferation-inducing gene 22 protein) Homo sapiens (Human) behavioral fear response [GO:0001662]; cAMP catabolic process [GO:0006198]; negative regulation of steroid hormone biosynthetic process [GO:0090032]; neuromuscular process controlling balance [GO:0050885]; operant conditioning [GO:0035106]; signal transduction [GO:0007165]; visual learning [GO:0008542] GO:0001662; GO:0004114; GO:0004115; GO:0005829; GO:0006198; GO:0007165; GO:0008542; GO:0035106; GO:0046872; GO:0050885; GO:0090032 4994 XM_044309836.1 546 529 434 1901 668 Q29RU2 2.06e-35 Oncoprotein-induced transcript 3 protein Bos taurus (Bovine) NA GO:0005509; GO:0005635 4995 XM_044326458.1 143 0 0 17 227 Q9Y2M2 5.73e-72 Protein SSUH2 homolog (Protein ssu-2 homolog) Homo sapiens (Human) odontogenesis [GO:0042476] GO:0005634; GO:0005737; GO:0031072; GO:0042476; GO:0051082 4996 XM_029324168.2 726 452 997 1374 1349 P80147 0 4-aminobutyrate aminotransferase, mitochondrial (EC 2.6.1.19) ((S)-3-amino-2-methylpropionate transaminase) (EC 2.6.1.22) (GABA aminotransferase) (GABA-AT) (Gamma-amino-N-butyrate transaminase) (GABA transaminase) (GABA-T) (L-AIBAT) Sus scrofa (Pig) behavioral response to cocaine [GO:0048148]; gamma-aminobutyric acid catabolic process [GO:0009450]; neurotransmitter catabolic process [GO:0042135] GO:0005739; GO:0005759; GO:0005829; GO:0009450; GO:0030170; GO:0032144; GO:0032145; GO:0034386; GO:0042135; GO:0042802; GO:0042803; GO:0046872; GO:0047298; GO:0048148; GO:0051537 4997 XM_044321356.1 0 458 249 0 0 Q96PY6 9.29e-146 Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase 1) (NimA-related protein kinase 1) (Renal carcinoma antigen NY-REN-55) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; cilium assembly [GO:0060271]; protein phosphorylation [GO:0006468] GO:0000242; GO:0004672; GO:0004674; GO:0004713; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0005829; GO:0006468; GO:0007049; GO:0016301; GO:0034451; GO:0046872; GO:0051301; GO:0060271; GO:0071889; GO:0106310 4998 XM_029353816.2 2613 2430 1765 2618 3236 O35286 0 ATP-dependent RNA helicase DHX15 (EC 3.6.4.13) (DEAH box protein 15) Mus musculus (Mouse) antiviral innate immune response [GO:0140374]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; mRNA processing [GO:0006397]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; response to alkaloid [GO:0043279]; response to toxic substance [GO:0009636]; RNA splicing [GO:0008380] GO:0003723; GO:0003724; GO:0003725; GO:0005524; GO:0005681; GO:0005689; GO:0005730; GO:0006397; GO:0008380; GO:0009636; GO:0016607; GO:0016887; GO:0042742; GO:0043123; GO:0043279; GO:0051607; GO:0071008; GO:0140374 4999 XR_003822802.2 99 133 109 168 167 NA NA NA NA NA NA 5000 XM_044307962.1 0 0 18 0 14 NA NA NA NA NA NA 5001 XM_029339344.2 496 137 219 236 190 NA NA NA NA NA NA 5002 XM_029332958.2 16181 22541 11208 19596 15712 P54632 2.85e-92 14-3-3-like protein Dictyostelium discoideum (Social amoeba) adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway [GO:0140582]; chemotaxis to cAMP [GO:0043327]; cleavage furrow ingression [GO:0036090]; cortical cytoskeleton organization [GO:0030865]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of cytokinesis [GO:0032467]; protein localization [GO:0008104]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; sorocarp development [GO:0030587] GO:0000226; GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007165; GO:0008104; GO:0009617; GO:0030587; GO:0030865; GO:0031012; GO:0032038; GO:0032467; GO:0036090; GO:0043327; GO:0045335; GO:0140582 5003 XM_044322284.1 0 2 12 0 1 NA NA NA NA NA NA 5004 XM_044328921.1 245 188 167 46 215 P09917 7.88e-46 Polyunsaturated fatty acid 5-lipoxygenase (EC 1.13.11.-) (Arachidonate 5-lipoxygenase) (5-LO) (5-lipoxygenase) (EC 1.13.11.34) Homo sapiens (Human) arachidonic acid metabolic process [GO:0019369]; dendritic cell migration [GO:0036336]; glucose homeostasis [GO:0042593]; hepoxilin biosynthetic process [GO:0051122]; humoral immune response [GO:0006959]; leukocyte chemotaxis involved in inflammatory response [GO:0002232]; leukocyte migration involved in inflammatory response [GO:0002523]; leukotriene A4 biosynthetic process [GO:1901753]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; leukotriene production involved in inflammatory response [GO:0002540]; linoleic acid metabolic process [GO:0043651]; lipid oxidation [GO:0034440]; lipoxin biosynthetic process [GO:2001301]; lipoxygenase pathway [GO:0019372]; long-chain fatty acid biosynthetic process [GO:0042759]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of inflammatory response [GO:0050728]; negative regulation of response to endoplasmic reticulum stress [GO:1903573]; negative regulation of sprouting angiogenesis [GO:1903671]; negative regulation of vascular wound healing [GO:0061044]; negative regulation of wound healing [GO:0061045]; positive regulation of bone mineralization [GO:0030501]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; regulation of cellular response to oxidative stress [GO:1900407]; regulation of cytokine production involved in inflammatory response [GO:1900015]; regulation of fat cell differentiation [GO:0045598]; regulation of inflammatory response [GO:0050727]; regulation of inflammatory response to wounding [GO:0106014]; regulation of insulin secretion [GO:0050796]; regulation of reactive oxygen species biosynthetic process [GO:1903426] GO:0001937; GO:0002232; GO:0002523; GO:0002540; GO:0004051; GO:0004052; GO:0005506; GO:0005576; GO:0005615; GO:0005635; GO:0005641; GO:0005654; GO:0005829; GO:0006691; GO:0006959; GO:0016363; GO:0016525; GO:0016702; GO:0016787; GO:0019369; GO:0019370; GO:0019372; GO:0030501; GO:0031965; GO:0034440; GO:0034774; GO:0036336; GO:0036403; GO:0042593; GO:0042759; GO:0043651; GO:0045598; GO:0048471; GO:0050727; GO:0050728; GO:0050796; GO:0051122; GO:0061044; GO:0061045; GO:0106014; GO:1900015; GO:1900407; GO:1901753; GO:1903426; GO:1903573; GO:1903671; GO:1904813; GO:1904999; GO:2001301 5005 XM_029344444.2 298 184 100 0 100 Q9H9Q4 9.44e-24 Non-homologous end-joining factor 1 (Protein cernunnos) (XRCC4-like factor) Homo sapiens (Human) B cell differentiation [GO:0030183]; central nervous system development [GO:0007417]; DNA ligation involved in DNA repair [GO:0051103]; double-strand break repair via nonhomologous end joining [GO:0006303]; immunoglobulin V(D)J recombination [GO:0033152]; positive regulation of ligase activity [GO:0051351]; response to ionizing radiation [GO:0010212]; T cell differentiation [GO:0030217] GO:0001650; GO:0005634; GO:0005654; GO:0006303; GO:0007417; GO:0010212; GO:0030183; GO:0030217; GO:0032807; GO:0033152; GO:0035861; GO:0045027; GO:0051103; GO:0051351; GO:0070182; GO:0070419 5006 XM_029326881.2 241 74 84 250 364 NA NA NA NA NA NA 5007 XR_006392898.1 41 2 25 5 151 NA NA NA NA NA NA 5008 XM_029332379.2 2494 835 864 1298 1304 NA NA NA NA NA NA 5009 XM_029332894.2 774 280 273 474 375 NA NA NA NA NA NA 5010 XM_029332932.2 41 103 45 125 159 P62262 2.12e-95 14-3-3 protein epsilon (14-3-3E) (Protein kinase C inhibitor protein 1) (KCIP-1) Ovis aries (Sheep) cellular response to heat [GO:0034605]; MAPK cascade [GO:0000165]; positive regulation of protein export from nucleus [GO:0046827]; protein localization to nucleus [GO:0034504] GO:0000165; GO:0005634; GO:0005737; GO:0034504; GO:0034605; GO:0042470; GO:0046827 5011 XR_006394968.1 0 29 22 9 56 NA NA NA NA NA NA 5012 XM_029333987.2 0 69 238 0 97 NA NA NA NA NA NA 5013 XM_044308601.1 34 14 394 213 62 Q91610 4.43e-21 Desert hedgehog protein A (EC 3.1.-.-) (Cephalic hedgehog protein) (Desert hedgehog protein 1) (DHH-1) (X-CHH) [Cleaved into: Desert hedgehog protein A N-product] Xenopus laevis (African clawed frog) cell-cell signaling [GO:0007267]; intein-mediated protein splicing [GO:0016539]; positive regulation of smoothened signaling pathway [GO:0045880]; protein autoprocessing [GO:0016540]; self proteolysis [GO:0097264]; system development [GO:0048731] GO:0000139; GO:0005113; GO:0005576; GO:0005789; GO:0005886; GO:0007267; GO:0008233; GO:0016539; GO:0016540; GO:0045880; GO:0046872; GO:0048731; GO:0097264; GO:0140853 5014 XM_029355465.2 68 32 25 74 37 Q9H6Z9 2.03e-66 Prolyl hydroxylase EGLN3 (EC 1.14.11.-) (Egl nine homolog 3) (EC 1.14.11.29) (HPH-1) (Hypoxia-inducible factor prolyl hydroxylase 3) (HIF-PH3) (HIF-prolyl hydroxylase 3) (HPH-3) (Prolyl hydroxylase domain-containing protein 3) (PHD3) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hypoxia [GO:0071456]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; protein hydroxylation [GO:0018126]; regulation of cell population proliferation [GO:0042127]; regulation of neuron apoptotic process [GO:0043523]; response to hypoxia [GO:0001666] GO:0001666; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006915; GO:0006919; GO:0006974; GO:0008198; GO:0016706; GO:0018126; GO:0018401; GO:0031418; GO:0031543; GO:0031545; GO:0042127; GO:0043523; GO:0071456 5015 XM_029323947.2 458 0 586 860 0 Q80YS9 2.9e-55 Serine/threonine kinase-like domain-containing protein STKLD1 (Serine/threonine kinase-like domain-containing protein 1) (Sugen kinase 071) Mus musculus (Mouse) protein phosphorylation [GO:0006468] GO:0004674; GO:0005524; GO:0006468 5016 XM_044314674.1 83 53 167 573 270 NA NA NA NA NA NA 5017 XR_003828368.2 1078 554 578 1217 970 Q5ZHS1 0 Elongator complex protein 3 (EC 2.3.1.-) (tRNA uridine(34) acetyltransferase) Gallus gallus (Chicken) regulation of transcription by RNA polymerase II [GO:0006357]; tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation [GO:0002926]; tRNA wobble uridine modification [GO:0002098] GO:0000049; GO:0002098; GO:0002926; GO:0005634; GO:0005737; GO:0006357; GO:0008607; GO:0033588; GO:0046872; GO:0051539; GO:0106261 5018 XM_044325244.1 2354 1500 1056 2043 2195 O04619 7.18e-72 Mitochondrial adenine nucleotide transporter ADNT1 (Adenine nucleotide transporter 1) Arabidopsis thaliana (Mouse-ear cress) NA GO:0005743; GO:0015297 5019 XM_044309563.1 188 17 139 78 374 NA NA NA NA NA NA 5020 XM_044316008.1 179 78 46 199 149 NA NA NA NA NA NA 5021 XM_044320593.1 15 6 9 4 7 Q9UBN7 2.08e-110 Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-) Homo sapiens (Human) aggresome assembly [GO:0070842]; autophagy [GO:0006914]; axonal transport of mitochondrion [GO:0019896]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to misfolded protein [GO:0071218]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to topologically incorrect protein [GO:0035967]; cilium assembly [GO:0060271]; cilium disassembly [GO:0061523]; collateral sprouting [GO:0048668]; dendritic spine morphogenesis [GO:0060997]; epigenetic regulation of gene expression [GO:0040029]; histone deacetylation [GO:0016575]; Hsp90 deacetylation [GO:0070846]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of protein-containing complex disassembly [GO:0043242]; negative regulation of proteolysis [GO:0045861]; negative regulation of transcription by RNA polymerase II [GO:0000122]; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:0061734]; peptidyl-lysine deacetylation [GO:0034983]; polyubiquitinated misfolded protein transport [GO:0070845]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of hydrogen peroxide-mediated programmed cell death [GO:1901300]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of tubulin deacetylation [GO:0090044]; protein deacetylation [GO:0006476]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; protein-containing complex disassembly [GO:0032984]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of autophagy [GO:0010506]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of establishment of protein localization [GO:0070201]; regulation of fat cell differentiation [GO:0045598]; regulation of macroautophagy [GO:0016241]; regulation of microtubule-based movement [GO:0060632]; regulation of protein stability [GO:0031647]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]; response to dexamethasone [GO:0071548]; response to growth factor [GO:0070848]; response to immobilization stress [GO:0035902]; response to misfolded protein [GO:0051788]; tubulin deacetylation [GO:0090042]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] GO:0000118; GO:0000122; GO:0000209; GO:0000978; GO:0001222; GO:0001975; GO:0003779; GO:0004407; GO:0005634; GO:0005654; GO:0005737; GO:0005771; GO:0005813; GO:0005829; GO:0005874; GO:0005875; GO:0005901; GO:0006476; GO:0006515; GO:0006886; GO:0006914; GO:0007026; GO:0008013; GO:0008017; GO:0008270; GO:0010506; GO:0010634; GO:0010727; GO:0016234; GO:0016235; GO:0016241; GO:0016575; GO:0019896; GO:0019899; GO:0030424; GO:0030425; GO:0031252; GO:0031333; GO:0031593; GO:0031625; GO:0031647; GO:0031648; GO:0032418; GO:0032984; GO:0033138; GO:0033558; GO:0034983; GO:0035902; GO:0035967; GO:0036064; GO:0040029; GO:0042826; GO:0042903; GO:0043014; GO:0043130; GO:0043162; GO:0043204; GO:0043242; GO:0045598; GO:0045861; GO:0045892; GO:0048156; GO:0048471; GO:0048487; GO:0048668; GO:0048843; GO:0050775; GO:0051354; GO:0051412; GO:0051787; GO:0051788; GO:0051879; GO:0051968; GO:0060271; GO:0060632; GO:0060765; GO:0060997; GO:0061523; GO:0061734; GO:0070201; GO:0070301; GO:0070840; GO:0070842; GO:0070845; GO:0070846; GO:0070848; GO:0071218; GO:0071374; GO:0071548; GO:0090042; GO:0090044; GO:1901300; GO:1901984; GO:1903146; GO:1903223; GO:1904056; GO:1904115; GO:2000273 5022 XM_044320593.1 15 6 9 4 7 Q9UBN7 4.48e-102 Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-) Homo sapiens (Human) aggresome assembly [GO:0070842]; autophagy [GO:0006914]; axonal transport of mitochondrion [GO:0019896]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to misfolded protein [GO:0071218]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to topologically incorrect protein [GO:0035967]; cilium assembly [GO:0060271]; cilium disassembly [GO:0061523]; collateral sprouting [GO:0048668]; dendritic spine morphogenesis [GO:0060997]; epigenetic regulation of gene expression [GO:0040029]; histone deacetylation [GO:0016575]; Hsp90 deacetylation [GO:0070846]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of protein-containing complex disassembly [GO:0043242]; negative regulation of proteolysis [GO:0045861]; negative regulation of transcription by RNA polymerase II [GO:0000122]; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:0061734]; peptidyl-lysine deacetylation [GO:0034983]; polyubiquitinated misfolded protein transport [GO:0070845]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of hydrogen peroxide-mediated programmed cell death [GO:1901300]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of tubulin deacetylation [GO:0090044]; protein deacetylation [GO:0006476]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; protein-containing complex disassembly [GO:0032984]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of autophagy [GO:0010506]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of establishment of protein localization [GO:0070201]; regulation of fat cell differentiation [GO:0045598]; regulation of macroautophagy [GO:0016241]; regulation of microtubule-based movement [GO:0060632]; regulation of protein stability [GO:0031647]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]; response to dexamethasone [GO:0071548]; response to growth factor [GO:0070848]; response to immobilization stress [GO:0035902]; response to misfolded protein [GO:0051788]; tubulin deacetylation [GO:0090042]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] GO:0000118; GO:0000122; GO:0000209; GO:0000978; GO:0001222; GO:0001975; GO:0003779; GO:0004407; GO:0005634; GO:0005654; GO:0005737; GO:0005771; GO:0005813; GO:0005829; GO:0005874; GO:0005875; GO:0005901; GO:0006476; GO:0006515; GO:0006886; GO:0006914; GO:0007026; GO:0008013; GO:0008017; GO:0008270; GO:0010506; GO:0010634; GO:0010727; GO:0016234; GO:0016235; GO:0016241; GO:0016575; GO:0019896; GO:0019899; GO:0030424; GO:0030425; GO:0031252; GO:0031333; GO:0031593; GO:0031625; GO:0031647; GO:0031648; GO:0032418; GO:0032984; GO:0033138; GO:0033558; GO:0034983; GO:0035902; GO:0035967; GO:0036064; GO:0040029; GO:0042826; GO:0042903; GO:0043014; GO:0043130; GO:0043162; GO:0043204; GO:0043242; GO:0045598; GO:0045861; GO:0045892; GO:0048156; GO:0048471; GO:0048487; GO:0048668; GO:0048843; GO:0050775; GO:0051354; GO:0051412; GO:0051787; GO:0051788; GO:0051879; GO:0051968; GO:0060271; GO:0060632; GO:0060765; GO:0060997; GO:0061523; GO:0061734; GO:0070201; GO:0070301; GO:0070840; GO:0070842; GO:0070845; GO:0070846; GO:0070848; GO:0071218; GO:0071374; GO:0071548; GO:0090042; GO:0090044; GO:1901300; GO:1901984; GO:1903146; GO:1903223; GO:1904056; GO:1904115; GO:2000273 5023 XR_006397952.1 20 19 44 23 101 Q6DBY0 0 Nuclear pore complex protein Nup85 (85 kDa nucleoporin) (Nucleoporin Nup85) (Pericentrin-1) Danio rerio (Zebrafish) (Brachydanio rerio) mRNA export from nucleus [GO:0006406]; nephron development [GO:0072006]; positive regulation of DNA-templated transcription [GO:0045893]; protein import into nucleus [GO:0006606] GO:0006406; GO:0006606; GO:0017056; GO:0031080; GO:0031965; GO:0045893; GO:0072006 5024 XM_029334206.2 33 29 17 27 36 NA NA NA NA NA NA 5025 XR_006391335.1 7 0 10 2 6 NA NA NA NA NA NA 5026 XM_044321586.1 0 13 0 0 25 NA NA NA NA NA NA 5027 XM_029355735.2 15 1 8 7 9 NA NA NA NA NA NA 5028 XM_044327754.1 556 153 185 230 249 NA NA NA NA NA NA 5029 XM_044308494.1 107 369 215 426 183 NA NA NA NA NA NA 5030 XM_029335136.2 146 107 52 368 74 NA NA NA NA NA NA 5031 XM_044328160.1 10 14 0 41 15 NA NA NA NA NA NA 5032 XM_029335243.2 4291 3428 2882 3726 2611 P54802 0 Alpha-N-acetylglucosaminidase (EC 3.2.1.50) (N-acetyl-alpha-glucosaminidase) (NAG) [Cleaved into: Alpha-N-acetylglucosaminidase 82 kDa form; Alpha-N-acetylglucosaminidase 77 kDa form] Homo sapiens (Human) cerebellar Purkinje cell layer development [GO:0021680]; heparan sulfate proteoglycan catabolic process [GO:0030200]; inner ear receptor cell development [GO:0060119]; locomotor rhythm [GO:0045475]; lysosome organization [GO:0007040]; middle ear morphogenesis [GO:0042474]; nervous system development [GO:0007399]; retinal rod cell development [GO:0046548] GO:0004561; GO:0005764; GO:0007040; GO:0007399; GO:0021680; GO:0030200; GO:0042474; GO:0043202; GO:0045475; GO:0046548; GO:0060119; GO:0070062 5033 XM_044323103.1 14 4 0 7 7 P04323 8.4e-63 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 5034 XM_029327400.2 10946 12828 5767 9918 7645 NA NA NA NA NA NA 5035 XM_044309595.1 22 8 6 67 50 NA NA NA NA NA NA 5036 XR_006396238.1 3 1 65 39 35 NA NA NA NA NA NA 5037 XM_029344289.2 455 336 300 460 578 Q28FX0 3.33e-89 ELAV-like protein 3 (Protein ElrC) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell differentiation [GO:0030154]; nervous system development [GO:0007399] GO:0003723; GO:0007399; GO:0030154; GO:1990904 5038 XR_003826098.2 0 0 1 6 2 NA NA NA NA NA NA 5039 XM_044319771.1 452 380 222 320 425 Q66KY3 3.2e-41 Protein CutA homolog Xenopus laevis (African clawed frog) response to metal ion [GO:0010038] GO:0010038 5040 XM_044311914.1 0 14 13 39 9 NA NA NA NA NA NA 5041 XM_029339635.2 0 42 0 52 40 G3UXB3 2.03e-42 NK1 transcription factor-related protein 1 (Homeobox protein SAX-2) (NKX-1.1) Mus musculus (Mouse) cell differentiation [GO:0030154]; lipid metabolic process [GO:0006629]; nervous system process [GO:0050877]; regulation of generation of precursor metabolites and energy [GO:0043467]; regulation of glucose metabolic process [GO:0010906]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0006629; GO:0010906; GO:0030154; GO:0043467; GO:0050877 5042 XM_044317879.1 95 26 28 0 200 Q5E9T8 6.47e-57 Mevalonate kinase (MK) (EC 2.7.1.36) Bos taurus (Bovine) cholesterol biosynthetic process [GO:0006695]; isopentenyl diphosphate biosynthetic process, mevalonate pathway [GO:0019287]; negative regulation of inflammatory response [GO:0050728]; phosphorylation [GO:0016310] GO:0000287; GO:0004496; GO:0005524; GO:0005777; GO:0005829; GO:0006695; GO:0016310; GO:0019287; GO:0042802; GO:0050728 5043 XM_044329169.1 9529 8631 6983 8256 7574 Q7ZYG4 1.35e-71 Osteoclast-stimulating factor 1 Xenopus laevis (African clawed frog) NA GO:0005737 5044 XM_029345047.2 384 334 339 241 411 Q0VCH3 3.54e-27 Cysteine-rich DPF motif domain-containing protein 1 Bos taurus (Bovine) NA NA 5045 XM_029328781.2 699 231 473 354 590 Q2XWK0 1.81e-152 Synaptic vesicle 2-related protein (SV2-related protein) Xenopus laevis (African clawed frog) NA GO:0022857; GO:0030672 5046 XR_006397541.1 5 22 0 1 6 NA NA NA NA NA NA 5047 XM_044324842.1 519 745 581 877 869 Q9WVF7 0 DNA polymerase epsilon catalytic subunit A (EC 2.7.7.7) (3'-5' exodeoxyribonuclease) (EC 3.1.11.-) (DNA polymerase II subunit A) Mus musculus (Mouse) base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; DNA replication proofreading [GO:0045004]; DNA synthesis involved in DNA repair [GO:0000731]; DNA-templated DNA replication [GO:0006261]; embryonic organ development [GO:0048568]; G1/S transition of mitotic cell cycle [GO:0000082]; leading strand elongation [GO:0006272]; mitotic cell cycle [GO:0000278]; nucleotide-excision repair, DNA gap filling [GO:0006297] GO:0000082; GO:0000166; GO:0000278; GO:0000731; GO:0003677; GO:0003682; GO:0003887; GO:0005634; GO:0005654; GO:0005886; GO:0006260; GO:0006261; GO:0006272; GO:0006287; GO:0006297; GO:0008270; GO:0008310; GO:0008622; GO:0045004; GO:0048568; GO:0051539; GO:0071897 5048 XM_029340563.2 1638 1670 872 1525 1404 NA NA NA NA NA NA 5049 XM_044315821.1 0 0 23 24 0 NA NA NA NA NA NA 5050 XR_006395064.1 0 0 9 10 0 NA NA NA NA NA NA 5051 XM_029352698.2 8801 5428 5357 8183 7090 B3P0K6 7.81e-53 Forkhead box protein O Drosophila erecta (Fruit fly) cell cycle [GO:0007049]; cell differentiation [GO:0030154]; glucose homeostasis [GO:0042593]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of insulin receptor signaling pathway [GO:0046627]; regulation of DNA-templated transcription [GO:0006355]; regulation of lipid metabolic process [GO:0019216] GO:0003700; GO:0005634; GO:0005737; GO:0006355; GO:0007049; GO:0008285; GO:0019216; GO:0030154; GO:0030308; GO:0042593; GO:0043565; GO:0046627 5052 XM_029331238.2 2777 3464 2534 3667 3054 Q9R0Q9 1.47e-65 Mannose-P-dolichol utilization defect 1 protein (Suppressor of Lec15 and Lec35 glycosylation mutation homolog) (SL15) Mus musculus (Mouse) oligosaccharide biosynthetic process [GO:0009312] GO:0009312; GO:0016020 5053 XR_003825909.2 5 63 19 14 162 NA NA NA NA NA NA 5054 XR_006393615.1 0 14 4 2 6 NA NA NA NA NA NA 5055 XM_044322464.1 0 0 0 0 164 Q96AY4 5.17e-82 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 5056 XM_044322464.1 0 0 0 0 164 Q96AY4 1.2e-80 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 5057 XM_044322464.1 0 0 0 0 164 Q96AY4 5.39e-77 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 5058 XM_044322464.1 0 0 0 0 164 Q96AY4 8.69e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 5059 XM_044322464.1 0 0 0 0 164 Q96AY4 1.8e-62 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 5060 XM_044322464.1 0 0 0 0 164 Q96AY4 1.12e-49 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 5061 XM_044324032.1 4 43 57 60 117 Q0V9W6 1.31e-82 BTB/POZ domain-containing protein 6 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737 5062 XM_029345082.2 0 0 0 31 48 Q6BZW3 8.87e-31 Protein BTN1 Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica) L-arginine transmembrane transport [GO:1903826]; lysine transport [GO:0015819]; regulation of intracellular pH [GO:0051453] GO:0000324; GO:0005773; GO:0005774; GO:0015819; GO:0022857; GO:0051453; GO:1903826 5063 XM_044314298.1 29 14 7 20 24 NA NA NA NA NA NA 5064 XR_003825639.2 533 473 349 694 649 P24822 1.95e-57 Intestinal-type alkaline phosphatase (IAP) (Intestinal alkaline phosphatase) (EC 3.1.3.1) (Alkaline phosphatase 3) Mus musculus (Mouse) dephosphorylation [GO:0016311]; multicellular organism growth [GO:0035264]; neural tube development [GO:0021915]; neurogenesis [GO:0022008]; phosphorus metabolic process [GO:0006793]; post-anal tail morphogenesis [GO:0036342] GO:0000287; GO:0002020; GO:0004035; GO:0005886; GO:0005903; GO:0006793; GO:0008270; GO:0009897; GO:0016311; GO:0021915; GO:0022008; GO:0035264; GO:0036342 5065 XR_003825639.2 533 473 349 694 649 P24822 1.95e-57 Intestinal-type alkaline phosphatase (IAP) (Intestinal alkaline phosphatase) (EC 3.1.3.1) (Alkaline phosphatase 3) Mus musculus (Mouse) dephosphorylation [GO:0016311]; multicellular organism growth [GO:0035264]; neural tube development [GO:0021915]; neurogenesis [GO:0022008]; phosphorus metabolic process [GO:0006793]; post-anal tail morphogenesis [GO:0036342] GO:0000287; GO:0002020; GO:0004035; GO:0005886; GO:0005903; GO:0006793; GO:0008270; GO:0009897; GO:0016311; GO:0021915; GO:0022008; GO:0035264; GO:0036342 5066 XR_003825639.2 533 473 349 694 649 P24822 2.11e-39 Intestinal-type alkaline phosphatase (IAP) (Intestinal alkaline phosphatase) (EC 3.1.3.1) (Alkaline phosphatase 3) Mus musculus (Mouse) dephosphorylation [GO:0016311]; multicellular organism growth [GO:0035264]; neural tube development [GO:0021915]; neurogenesis [GO:0022008]; phosphorus metabolic process [GO:0006793]; post-anal tail morphogenesis [GO:0036342] GO:0000287; GO:0002020; GO:0004035; GO:0005886; GO:0005903; GO:0006793; GO:0008270; GO:0009897; GO:0016311; GO:0021915; GO:0022008; GO:0035264; GO:0036342 5067 XR_003825639.2 533 473 349 694 649 P24822 2.11e-39 Intestinal-type alkaline phosphatase (IAP) (Intestinal alkaline phosphatase) (EC 3.1.3.1) (Alkaline phosphatase 3) Mus musculus (Mouse) dephosphorylation [GO:0016311]; multicellular organism growth [GO:0035264]; neural tube development [GO:0021915]; neurogenesis [GO:0022008]; phosphorus metabolic process [GO:0006793]; post-anal tail morphogenesis [GO:0036342] GO:0000287; GO:0002020; GO:0004035; GO:0005886; GO:0005903; GO:0006793; GO:0008270; GO:0009897; GO:0016311; GO:0021915; GO:0022008; GO:0035264; GO:0036342 5068 XM_029341427.2 65 28 54 44 37 NA NA NA NA NA NA 5069 XM_029338717.2 86 235 101 152 27 NA NA NA NA NA NA 5070 XM_044327254.1 362 327 371 463 497 Q52KG5 7.44e-121 Kinesin-like protein KIF26A Mus musculus (Mouse) enteric nervous system development [GO:0048484]; negative regulation of signal transduction [GO:0009968]; regulation of cell growth by extracellular stimulus [GO:0001560] GO:0001560; GO:0005524; GO:0005737; GO:0005871; GO:0005874; GO:0008017; GO:0009968; GO:0048484 5071 XM_044323075.1 23 5 3 0 71 NA NA NA NA NA NA 5072 XM_044328711.1 0 1 15 19 20 NA NA NA NA NA NA 5073 XM_029335957.2 295 142 68 285 161 F1LV46 3.39e-98 Indoleamine 2,3-dioxygenase 2 (IDO-2) (EC 1.13.11.-) (Indoleamine 2,3-dioxygenase-like protein 1) (Indoleamine-pyrrole 2,3-dioxygenase-like protein 1) Rattus norvegicus (Rat) 'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; immune system process [GO:0002376]; tryptophan catabolic process to kynurenine [GO:0019441] GO:0002376; GO:0004833; GO:0005737; GO:0019441; GO:0020037; GO:0033754; GO:0034354; GO:0046872 5074 XR_006397133.1 81 101 64 7 44 NA NA NA NA NA NA 5075 XM_044323731.1 44 22 28 42 53 NA NA NA NA NA NA 5076 XM_044327437.1 123 50 81 26 111 NA NA NA NA NA NA 5077 XM_044308438.1 134 29 36 56 99 Q6LAF1 4.62e-47 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 5078 XR_006392105.1 7 0 34 20 6 NA NA NA NA NA NA 5079 XM_029350415.2 3 0 0 0 71 NA NA NA NA NA NA 5080 XM_029331863.2 2393 1789 1200 1887 1877 Q8WV41 3.55e-116 Sorting nexin-33 (SH3 and PX domain-containing protein 3) Homo sapiens (Human) cleavage furrow formation [GO:0036089]; endocytosis [GO:0006897]; endosomal transport [GO:0016197]; endosome organization [GO:0007032]; intracellular protein transport [GO:0006886]; macropinocytosis [GO:0044351]; mitotic cytokinesis [GO:0000281]; negative regulation of endocytosis [GO:0045806]; negative regulation of protein localization to cell surface [GO:2000009]; plasma membrane tubulation [GO:0097320]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of protein localization to cell surface [GO:2000010]; protein import [GO:0017038] GO:0000281; GO:0005829; GO:0005886; GO:0006886; GO:0006897; GO:0007032; GO:0016020; GO:0016197; GO:0017038; GO:0019898; GO:0030659; GO:0031410; GO:0035091; GO:0036089; GO:0042802; GO:0044351; GO:0045806; GO:0051044; GO:0097320; GO:2000009; GO:2000010 5081 XM_029333231.2 343 197 186 170 191 O08755 8.85e-49 Hepatocyte nuclear factor 6 (HNF-6) (One cut domain family member 1) (One cut homeobox 1) Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; B cell differentiation [GO:0030183]; cell fate commitment [GO:0045165]; cell migration [GO:0016477]; cilium assembly [GO:0060271]; endocrine pancreas development [GO:0031018]; endoderm development [GO:0007492]; enteroendocrine cell differentiation [GO:0035883]; epithelial cell development [GO:0002064]; glucose metabolic process [GO:0006006]; liver development [GO:0001889]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; Notch signaling pathway [GO:0007219]; pancreas development [GO:0031016]; pancreatic A cell differentiation [GO:0003310]; pancreatic D cell differentiation [GO:0003311]; positive regulation of cell migration [GO:0030335]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell-matrix adhesion [GO:0001952]; regulation of transcription by RNA polymerase II [GO:0006357]; spleen development [GO:0048536]; transforming growth factor beta receptor signaling pathway [GO:0007179]; type B pancreatic cell differentiation [GO:0003309] GO:0000978; GO:0000981; GO:0001228; GO:0001889; GO:0001952; GO:0002064; GO:0003309; GO:0003310; GO:0003311; GO:0003677; GO:0003682; GO:0003700; GO:0005634; GO:0005654; GO:0006006; GO:0006357; GO:0007179; GO:0007219; GO:0007492; GO:0009653; GO:0016477; GO:0030183; GO:0030335; GO:0030512; GO:0031016; GO:0031018; GO:0035883; GO:0045165; GO:0045944; GO:0048536; GO:0060271; GO:1990837 5082 XR_006396285.1 173 111 162 155 105 NA NA NA NA NA NA 5083 XM_044311441.1 186 206 108 283 803 Q08B63 8.22e-139 Lysyl oxidase homolog 2 (EC 1.4.3.13) (Lysyl oxidase-like protein 2) Xenopus laevis (African clawed frog) collagen fibril organization [GO:0030199]; endothelial cell migration [GO:0043542]; endothelial cell proliferation [GO:0001935]; epithelial to mesenchymal transition [GO:0001837]; heterochromatin organization [GO:0070828]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of stem cell population maintenance [GO:1902455]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-lysine oxidation [GO:0018057]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; protein modification process [GO:0036211]; response to copper ion [GO:0046688]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040] GO:0000122; GO:0000785; GO:0001666; GO:0001837; GO:0001935; GO:0002040; GO:0004720; GO:0005044; GO:0005507; GO:0005509; GO:0005604; GO:0005615; GO:0005634; GO:0005783; GO:0010718; GO:0016020; GO:0018057; GO:0030199; GO:0032332; GO:0036211; GO:0043542; GO:0045892; GO:0046688; GO:0070492; GO:0070828; GO:1902455 5084 XM_029353722.2 674 501 415 892 851 Q68FS4 3.6e-171 Cytosol aminopeptidase (EC 3.4.11.1) (Cysteinylglycine-S-conjugate dipeptidase) (EC 3.4.13.23) (Leucine aminopeptidase 3) (LAP-3) (Leucyl aminopeptidase) (LAP) (Peptidase S) (Proline aminopeptidase) (EC 3.4.11.5) (Prolyl aminopeptidase) Rattus norvegicus (Rat) proteolysis [GO:0006508] GO:0004180; GO:0005737; GO:0005802; GO:0006508; GO:0008233; GO:0030145; GO:0070006 5085 XM_029351903.2 359 254 323 217 409 Q9H892 2.68e-74 Tetratricopeptide repeat protein 12 (TPR repeat protein 12) Homo sapiens (Human) axonemal dynein complex assembly [GO:0070286]; sperm axoneme assembly [GO:0007288] GO:0005737; GO:0005813; GO:0007288; GO:0070286 5086 XM_029342496.2 219 48 55 11 80 NA NA NA NA NA NA 5087 XM_044312175.1 0 10 0 6 0 NA NA NA NA NA NA 5088 XM_044315085.1 104 133 0 29 22 NA NA NA NA NA NA 5089 XM_029342162.2 3700 2918 2412 2205 1810 O60573 7.1e-106 Eukaryotic translation initiation factor 4E type 2 (eIF-4E type 2) (eIF4E type 2) (Eukaryotic translation initiation factor 4E homologous protein) (Eukaryotic translation initiation factor 4E-like 3) (eIF4E-like protein 4E-LP) (mRNA cap-binding protein 4EHP) (h4EHP) (mRNA cap-binding protein type 3) Homo sapiens (Human) miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148] GO:0000339; GO:0000340; GO:0000932; GO:0003723; GO:0003743; GO:0005737; GO:0005829; GO:0005845; GO:0008135; GO:0016281; GO:0017148; GO:0031625; GO:0035278 5090 XM_044307516.1 0 0 10 5 0 NA NA NA NA NA NA 5091 XM_044318672.1 117 137 143 166 208 Q6DEW6 2.22e-72 RNA exonuclease 4 (EC 3.1.-.-) (Exonuclease XPMC2) (Prevents mitotic catastrophe 2 protein) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) rRNA processing [GO:0006364] GO:0003676; GO:0005634; GO:0006364; GO:0008408 5092 XR_006397884.1 77 34 31 25 88 NA NA NA NA NA NA 5093 XM_029327389.2 1 0 320 12 1626 Q8C033 1.02e-138 Rho guanine nucleotide exchange factor 10 Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; activation of GTPase activity [GO:0090630]; centrosome duplication [GO:0051298]; mitotic spindle assembly [GO:0090307]; myelination in peripheral nervous system [GO:0022011]; positive regulation of stress fiber assembly [GO:0051496] GO:0005085; GO:0005813; GO:0019894; GO:0022011; GO:0030036; GO:0051298; GO:0051496; GO:0090307; GO:0090630 5094 XM_029353429.2 177 41 145 63 601 P47747 2.34e-30 Histamine H2 receptor (H2R) (HH2R) (Gastric receptor I) Cavia porcellus (Guinea pig) gastric acid secretion [GO:0001696]; positive regulation of vasoconstriction [GO:0045907] GO:0001696; GO:0004969; GO:0005886; GO:0045907 5095 XM_029328095.2 185 80 64 143 90 NA NA NA NA NA NA 5096 XM_029324256.2 614 312 286 293 420 NA NA NA NA NA NA 5097 XM_044325270.1 123 0 98 37 729 P98133 2.81e-24 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 5098 XM_044325270.1 123 0 98 37 729 P98133 3.71e-23 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 5099 XM_029329867.2 679 1415 415 1315 2608 P20072 1.91e-70 Annexin A7 (Annexin VII) (Annexin-7) (Synexin) Bos taurus (Bovine) NA GO:0005509; GO:0005544; GO:0005634; GO:0005737; GO:0042584 5100 XM_029340678.2 1164 1269 686 1237 636 NA NA NA NA NA NA 5101 XM_029348533.2 50 0 0 0 8 D3YXG0 1.09e-24 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 5102 XM_029348533.2 50 0 0 0 8 D3YXG0 8.92e-22 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 5103 XM_029325912.2 36 4 55 128 197 Q9U6Y6 5.11e-46 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 5104 XR_003827384.2 161 169 106 241 134 NA NA NA NA NA NA 5105 XM_044312509.1 0 0 6 0 0 NA NA NA NA NA NA 5106 XM_044308094.1 734 770 632 638 406 O00471 0 Exocyst complex component 5 (Exocyst complex component Sec10) (hSec10) Homo sapiens (Human) epithelial cell apoptotic process [GO:1904019]; establishment of planar polarity [GO:0001736]; exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; membrane fission [GO:0090148]; mitotic cytokinesis [GO:0000281]; non-motile cilium assembly [GO:1905515]; post-Golgi vesicle-mediated transport [GO:0006892]; protein localization to plasma membrane [GO:0072659]; protein transport [GO:0015031]; vesicle docking involved in exocytosis [GO:0006904]; vesicle tethering involved in exocytosis [GO:0090522] GO:0000145; GO:0000281; GO:0001736; GO:0005737; GO:0005829; GO:0006887; GO:0006892; GO:0006893; GO:0006904; GO:0015031; GO:0030496; GO:0031267; GO:0047485; GO:0072659; GO:0090148; GO:0090522; GO:1904019; GO:1905515 5107 XM_044316436.1 0 7 0 4 0 NA NA NA NA NA NA 5108 XM_044315248.1 12 1 18 0 23 NA NA NA NA NA NA 5109 XM_029332192.2 6 4 0 383 409 NA NA NA NA NA NA 5110 XM_044328156.1 0 0 0 9 0 NA NA NA NA NA NA 5111 XM_044318019.1 142 231 143 85 92 NA NA NA NA NA NA 5112 XM_044326945.1 0 60 0 48 0 NA NA NA NA NA NA 5113 XM_044323673.1 0 20 0 0 0 NA NA NA NA NA NA 5114 XM_029337891.2 223 109 152 154 170 NA NA NA NA NA NA 5115 XM_029332729.2 10467 18608 10153 11846 9096 Q95WA0 1.2e-60 60S ribosomal protein L26 Littorina littorea (Common periwinkle) translation [GO:0006412] GO:0003723; GO:0003735; GO:0006412; GO:0015934 5116 XM_029338414.2 812 490 709 429 204 Q8BZI6 1.36e-45 Protein GUCD1 (Guanylyl cyclase domain-containing protein 1) (Protein LLN4) Mus musculus (Mouse) NA NA 5117 XM_029324453.2 422 336 299 336 604 Q96I24 5.32e-73 Far upstream element-binding protein 3 (FUSE-binding protein 3) Homo sapiens (Human) DNA-templated transcription [GO:0006351]; intracellular mRNA localization [GO:0008298]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression [GO:0010468] GO:0003697; GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0005737; GO:0005840; GO:0005844; GO:0006351; GO:0008298; GO:0010468; GO:0010628; GO:0016020; GO:0043025; GO:0043198; GO:0045893; GO:0045944 5118 XM_044311846.1 0 0 2 0 8 Q80XJ3 2.27e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 5119 XM_044324564.1 10 6 0 16 26 NA NA NA NA NA NA 5120 XM_044308768.1 304 321 221 418 293 Q0KIA2 2.83e-52 PP2C-like domain-containing protein CG9801 Drosophila melanogaster (Fruit fly) NA NA 5121 XM_044320932.1 2 97 0 21 121 NA NA NA NA NA NA 5122 XM_044310737.1 19 6 0 0 24 NA NA NA NA NA NA 5123 XM_029332041.2 35 1 17 17 39 NA NA NA NA NA NA 5124 XM_044321004.1 0 85 34 0 0 A2ASQ1 7.32e-22 Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment (C90); Agrin C-terminal 22 kDa fragment (C22)] Mus musculus (Mouse) animal organ morphogenesis [GO:0009887]; cell differentiation [GO:0030154]; chemical synaptic transmission [GO:0007268]; motor neuron apoptotic process [GO:0097049]; negative regulation of P-type sodium:potassium-exchanging transporter activity [GO:1903407]; negative regulation of sodium ion export across plasma membrane [GO:1903277]; neuromuscular junction development [GO:0007528]; neurotransmitter receptor metabolic process [GO:0045213]; plasma membrane organization [GO:0007009]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of motor neuron apoptotic process [GO:2000673]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein binding [GO:0032092]; positive regulation of protein geranylgeranylation [GO:2000541]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of synaptic assembly at neuromuscular junction [GO:0045887]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor clustering [GO:0043113]; regulation of axon guidance [GO:1902667]; regulation of cardiac muscle cell membrane potential [GO:0086036]; regulation of cardiac muscle contraction [GO:0055117]; regulation of GTPase activity [GO:0043087]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of protein phosphorylation [GO:0001932]; regulation of synapse organization [GO:0050807]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse assembly [GO:0007416]; tissue development [GO:0009888] GO:0001932; GO:0001934; GO:0002162; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005796; GO:0007009; GO:0007268; GO:0007416; GO:0007528; GO:0009887; GO:0009888; GO:0009986; GO:0030154; GO:0030548; GO:0032092; GO:0033691; GO:0035374; GO:0036122; GO:0042030; GO:0042383; GO:0043083; GO:0043087; GO:0043113; GO:0043395; GO:0043547; GO:0044295; GO:0044325; GO:0045202; GO:0045213; GO:0045887; GO:0045944; GO:0050431; GO:0050731; GO:0050807; GO:0051491; GO:0055117; GO:0061098; GO:0062023; GO:0070507; GO:0071340; GO:0086036; GO:0097049; GO:0098978; GO:1902667; GO:1903277; GO:1903407; GO:2000541; GO:2000673 5125 XM_044313638.1 49 10 2 13 32 NA NA NA NA NA NA 5126 XM_044328746.1 8535 8590 6464 6021 3265 P50616 2.28e-43 Protein Tob1 (Transducer of erbB-2 1) Homo sapiens (Human) negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060212]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of translation [GO:0017148]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; regulation of gene expression [GO:0010468]; regulation of SMAD protein signal transduction [GO:0060390] GO:0003714; GO:0005634; GO:0005737; GO:0008285; GO:0010468; GO:0017148; GO:0030014; GO:0030514; GO:0030971; GO:0045668; GO:0046332; GO:0060212; GO:0060213; GO:0060390; GO:1900153 5127 XM_029342022.2 11 0 0 6 2 NA NA NA NA NA NA 5128 XM_029348753.2 1205 1311 984 1028 922 Q5SX19 2.25e-64 N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase (EC 3.5.1.89) (Phosphatidylinositol-glycan biosynthesis class L protein) (PIG-L) Mus musculus (Mouse) GPI anchor biosynthetic process [GO:0006506] GO:0000225; GO:0005783; GO:0005789; GO:0006506; GO:0016811 5129 XM_029341553.2 167 19 0 27 0 NA NA NA NA NA NA 5130 XM_044309772.1 183 48 64 149 204 NA NA NA NA NA NA 5131 XM_029335739.2 0 12 2 0 0 Q2KIP6 4.08e-23 Kappa-type opioid receptor (K-OR-1) (KOR-1) Bos taurus (Bovine) adenylate cyclase-inhibiting opioid receptor signaling pathway [GO:0031635]; defense response to virus [GO:0051607]; G protein-coupled opioid receptor signaling pathway [GO:0038003]; immune response [GO:0006955]; locomotory behavior [GO:0007626]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; regulation of saliva secretion [GO:0046877]; sensory perception of pain [GO:0019233] GO:0004930; GO:0004985; GO:0005654; GO:0005829; GO:0005886; GO:0006955; GO:0007200; GO:0007218; GO:0007626; GO:0016020; GO:0019233; GO:0031635; GO:0038003; GO:0038048; GO:0042277; GO:0042923; GO:0043005; GO:0046877; GO:0051607 5132 XM_029337340.2 166 55 0 33 126 NA NA NA NA NA NA 5133 XM_029352111.2 544 261 199 547 453 NA NA NA NA NA NA 5134 XR_003823569.2 150 347 487 229 182 NA NA NA NA NA NA 5135 XM_044316736.1 71 154 0 0 0 NA NA NA NA NA NA 5136 XM_044319005.1 0 0 0 10 162 Q96BK5 3.43e-42 PIN2/TERF1-interacting telomerase inhibitor 1 (Liver-related putative tumor suppressor) (Pin2-interacting protein X1) (Protein 67-11-3) (TRF1-interacting protein 1) Homo sapiens (Human) mitotic metaphase plate congression [GO:0007080]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of protein localization to nucleolus [GO:1904751]; positive regulation of telomeric DNA binding [GO:1904744]; protein localization to chromosome, telomeric region [GO:0070198]; protein localization to nucleolus [GO:1902570]; regulation of protein stability [GO:0031647]; regulation of telomerase activity [GO:0051972]; ribosomal small subunit biogenesis [GO:0042274]; telomere maintenance via telomerase [GO:0007004] GO:0000228; GO:0000776; GO:0000781; GO:0005654; GO:0005730; GO:0005739; GO:0005819; GO:0007004; GO:0007080; GO:0008285; GO:0010521; GO:0010972; GO:0031397; GO:0031647; GO:0032211; GO:0042274; GO:0044877; GO:0051972; GO:0051974; GO:0070034; GO:0070198; GO:1902570; GO:1904357; GO:1904744; GO:1904751 5137 XM_044309175.1 20 891 0 0 0 NA NA NA NA NA NA 5138 XM_029335115.2 451 427 409 382 490 NA NA NA NA NA NA 5139 XM_029324084.2 6 0 2 16 1 NA NA NA NA NA NA 5140 XM_044309440.1 25 3 5 8 5 NA NA NA NA NA NA 5141 XR_006394449.1 145 70 148 194 337 NA NA NA NA NA NA 5142 XM_044325326.1 21 1 16 8 31 A6QLU6 1.58e-65 Adhesion G-protein coupled receptor D1 (G-protein coupled receptor 133) Bos taurus (Bovine) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0005886; GO:0007166; GO:0007186; GO:0007189 5143 XR_006393285.1 262 57 77 151 107 NA NA NA NA NA NA 5144 XM_029358541.2 1578 2241 895 1194 937 Q6NVU2 5.13e-150 Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell division [GO:0051301]; glycogen metabolic process [GO:0005977]; mitotic nuclear membrane reassembly [GO:0007084]; protein dephosphorylation [GO:0006470] GO:0000776; GO:0004722; GO:0005730; GO:0005739; GO:0005856; GO:0005977; GO:0006470; GO:0007084; GO:0016607; GO:0017018; GO:0030496; GO:0032154; GO:0046872; GO:0051301 5145 XM_044319142.1 139 237 134 291 369 P0DX22 1.23e-56 NA NA NA NA 5146 XM_044326966.1 32 9 42 16 249 NA NA NA NA NA NA 5147 XM_044314249.1 0 0 0 0 87 NA NA NA NA NA NA 5148 XM_029340664.2 924 943 645 338 635 Q6P0C6 3.68e-48 LHFPL tetraspan subfamily member 2a protein Danio rerio (Zebrafish) (Brachydanio rerio) development of primary female sexual characteristics [GO:0046545]; development of primary male sexual characteristics [GO:0046546]; positive regulation of fertilization [GO:1905516]; single fertilization [GO:0007338] GO:0007338; GO:0016020; GO:0046545; GO:0046546; GO:1905516 5149 XM_044316045.1 0 0 0 16 0 NA NA NA NA NA NA 5150 XM_044317017.1 354 213 253 273 371 Q8C206 9.92e-32 G-protein coupled receptor 157 Mus musculus (Mouse) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; circadian behavior [GO:0048512]; G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; radial glial cell differentiation [GO:0060019] GO:0004930; GO:0005886; GO:0007166; GO:0007186; GO:0007189; GO:0048512; GO:0051482; GO:0060019; GO:0060170 5151 XM_029347168.2 122 222 34 132 0 NA NA NA NA NA NA 5152 XM_044316716.1 273 206 55 91 167 P02752 2.93e-36 Riboflavin-binding protein (RBP) [Cleaved into: Riboflavin-binding protein, plasma form; Riboflavin-binding protein, yolk major form; Riboflavin-binding protein, yolk minor form] Gallus gallus (Chicken) negative regulation of sensory perception of bitter taste [GO:1904661]; negative regulation of sensory perception of sweet taste [GO:1904657]; riboflavin transport [GO:0032218] GO:0009897; GO:0032217; GO:0032218; GO:0038023; GO:1902444; GO:1904657; GO:1904661 5153 XM_029349953.2 1135 0 92 0 0 O42097 4.19e-71 Hepatocyte nuclear factor 3-beta (HNF-3-beta) (HNF-3B) (Forkhead box protein A2) (Me-HNF3B) Oryzias latipes (Japanese rice fish) (Japanese killifish) anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; regulation of transcription by RNA polymerase II [GO:0006357]; system development [GO:0048731] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0009653; GO:0019904; GO:0030154; GO:0048731 5154 XM_029346092.2 0 123 99 257 63 NA NA NA NA NA NA 5155 XM_029328772.2 782 397 231 563 551 Q5ZKJ5 4.88e-65 Transmembrane protein 180 (Major facilitator superfamily domain-containing 13A) Gallus gallus (Chicken) NA GO:0016020 5156 XR_006394488.1 0 0 0 74 0 NA NA NA NA NA NA 5157 XM_029323481.2 3 3 1 3 25 NA NA NA NA NA NA 5158 XM_044308514.1 102 78 74 517 135 NA NA NA NA NA NA 5159 XM_044323881.1 1844 1134 1491 2597 3072 F8VQB6 0 Unconventional myosin-X (Unconventional myosin-10) Mus musculus (Mouse) cell motility [GO:0048870]; cytoskeleton-dependent intracellular transport [GO:0030705]; positive regulation of cell-cell adhesion [GO:0022409]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489] GO:0000146; GO:0001726; GO:0005516; GO:0005524; GO:0005547; GO:0005730; GO:0005829; GO:0005886; GO:0005938; GO:0008360; GO:0016459; GO:0022409; GO:0030027; GO:0030175; GO:0030507; GO:0030705; GO:0031527; GO:0032433; GO:0043005; GO:0043025; GO:0048870; GO:0051015; GO:0051489; GO:0060002 5160 XM_044323881.1 1844 1134 1491 2597 3072 F8VQB6 0 Unconventional myosin-X (Unconventional myosin-10) Mus musculus (Mouse) cell motility [GO:0048870]; cytoskeleton-dependent intracellular transport [GO:0030705]; positive regulation of cell-cell adhesion [GO:0022409]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489] GO:0000146; GO:0001726; GO:0005516; GO:0005524; GO:0005547; GO:0005730; GO:0005829; GO:0005886; GO:0005938; GO:0008360; GO:0016459; GO:0022409; GO:0030027; GO:0030175; GO:0030507; GO:0030705; GO:0031527; GO:0032433; GO:0043005; GO:0043025; GO:0048870; GO:0051015; GO:0051489; GO:0060002 5161 XM_029345820.2 65 23 37 58 44 Q96LD8 4.36e-57 Sentrin-specific protease 8 (EC 3.4.22.-) (Deneddylase-1) (NEDD8-specific protease 1) (Protease, cysteine 2) (Sentrin/SUMO-specific protease SENP8) Homo sapiens (Human) post-translational protein modification [GO:0043687]; protein deneddylation [GO:0000338]; protein deubiquitination [GO:0016579] GO:0000338; GO:0005829; GO:0008234; GO:0016579; GO:0019784; GO:0043687 5162 XM_029329773.2 286 3 801 160 1181 P79134 1.02e-72 Annexin A6 (Annexin VI) (Annexin-6) Bos taurus (Bovine) apoptotic signaling pathway [GO:0097190]; biomineral tissue development [GO:0031214]; calcium ion import [GO:0070509]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; growth plate cartilage chondrocyte differentiation [GO:0003418]; mitochondrial calcium ion homeostasis [GO:0051560]; negative regulation of sequestering of calcium ion [GO:0051283]; neural crest cell migration [GO:0001755]; plasma membrane repair [GO:0001778]; regulation of muscle contraction [GO:0006937] GO:0001725; GO:0001755; GO:0001778; GO:0001786; GO:0003418; GO:0005262; GO:0005509; GO:0005525; GO:0005544; GO:0005737; GO:0005886; GO:0005925; GO:0006816; GO:0006937; GO:0008201; GO:0015276; GO:0015485; GO:0016020; GO:0019899; GO:0030061; GO:0031214; GO:0031982; GO:0035374; GO:0038024; GO:0042470; GO:0042584; GO:0048306; GO:0048471; GO:0051015; GO:0051283; GO:0051560; GO:0070509; GO:0070588; GO:0097190 5163 XM_029329773.2 286 3 801 160 1181 P79134 2.29e-59 Annexin A6 (Annexin VI) (Annexin-6) Bos taurus (Bovine) apoptotic signaling pathway [GO:0097190]; biomineral tissue development [GO:0031214]; calcium ion import [GO:0070509]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; growth plate cartilage chondrocyte differentiation [GO:0003418]; mitochondrial calcium ion homeostasis [GO:0051560]; negative regulation of sequestering of calcium ion [GO:0051283]; neural crest cell migration [GO:0001755]; plasma membrane repair [GO:0001778]; regulation of muscle contraction [GO:0006937] GO:0001725; GO:0001755; GO:0001778; GO:0001786; GO:0003418; GO:0005262; GO:0005509; GO:0005525; GO:0005544; GO:0005737; GO:0005886; GO:0005925; GO:0006816; GO:0006937; GO:0008201; GO:0015276; GO:0015485; GO:0016020; GO:0019899; GO:0030061; GO:0031214; GO:0031982; GO:0035374; GO:0038024; GO:0042470; GO:0042584; GO:0048306; GO:0048471; GO:0051015; GO:0051283; GO:0051560; GO:0070509; GO:0070588; GO:0097190 5164 XM_029329773.2 286 3 801 160 1181 P79134 3.01e-38 Annexin A6 (Annexin VI) (Annexin-6) Bos taurus (Bovine) apoptotic signaling pathway [GO:0097190]; biomineral tissue development [GO:0031214]; calcium ion import [GO:0070509]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; growth plate cartilage chondrocyte differentiation [GO:0003418]; mitochondrial calcium ion homeostasis [GO:0051560]; negative regulation of sequestering of calcium ion [GO:0051283]; neural crest cell migration [GO:0001755]; plasma membrane repair [GO:0001778]; regulation of muscle contraction [GO:0006937] GO:0001725; GO:0001755; GO:0001778; GO:0001786; GO:0003418; GO:0005262; GO:0005509; GO:0005525; GO:0005544; GO:0005737; GO:0005886; GO:0005925; GO:0006816; GO:0006937; GO:0008201; GO:0015276; GO:0015485; GO:0016020; GO:0019899; GO:0030061; GO:0031214; GO:0031982; GO:0035374; GO:0038024; GO:0042470; GO:0042584; GO:0048306; GO:0048471; GO:0051015; GO:0051283; GO:0051560; GO:0070509; GO:0070588; GO:0097190 5165 XM_029329773.2 286 3 801 160 1181 P79134 1.76e-34 Annexin A6 (Annexin VI) (Annexin-6) Bos taurus (Bovine) apoptotic signaling pathway [GO:0097190]; biomineral tissue development [GO:0031214]; calcium ion import [GO:0070509]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; growth plate cartilage chondrocyte differentiation [GO:0003418]; mitochondrial calcium ion homeostasis [GO:0051560]; negative regulation of sequestering of calcium ion [GO:0051283]; neural crest cell migration [GO:0001755]; plasma membrane repair [GO:0001778]; regulation of muscle contraction [GO:0006937] GO:0001725; GO:0001755; GO:0001778; GO:0001786; GO:0003418; GO:0005262; GO:0005509; GO:0005525; GO:0005544; GO:0005737; GO:0005886; GO:0005925; GO:0006816; GO:0006937; GO:0008201; GO:0015276; GO:0015485; GO:0016020; GO:0019899; GO:0030061; GO:0031214; GO:0031982; GO:0035374; GO:0038024; GO:0042470; GO:0042584; GO:0048306; GO:0048471; GO:0051015; GO:0051283; GO:0051560; GO:0070509; GO:0070588; GO:0097190 5166 XM_044314902.1 14 5 16 10 30 NA NA NA NA NA NA 5167 XR_006392185.1 0 5 0 0 22 NA NA NA NA NA NA 5168 XM_029335766.2 11 13 23 5 48 O02813 3.14e-21 Neuropeptide Y receptor type 1 (NPY1-R) Canis lupus familiaris (Dog) (Canis familiaris) feeding behavior [GO:0007631]; glucose metabolic process [GO:0006006]; locomotory behavior [GO:0007626]; outflow tract morphogenesis [GO:0003151]; regulation of blood pressure [GO:0008217]; regulation of multicellular organism growth [GO:0040014]; sensory perception of pain [GO:0019233] GO:0001601; GO:0001602; GO:0003151; GO:0005886; GO:0006006; GO:0007626; GO:0007631; GO:0008188; GO:0008217; GO:0019233; GO:0040014; GO:0042923; GO:0043005 5169 XM_044308980.1 142 40 79 308 163 Q96RW7 6.82e-28 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 5170 XM_044308980.1 142 40 79 308 163 Q96RW7 2.52e-23 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 5171 XM_044308980.1 142 40 79 308 163 Q96RW7 4.66e-22 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 5172 XM_044308980.1 142 40 79 308 163 Q96RW7 6.86e-22 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 5173 XM_044308980.1 142 40 79 308 163 Q96RW7 1.73e-21 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 5174 XM_044308980.1 142 40 79 308 163 Q96RW7 2.45e-21 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 5175 XR_006391381.1 44 5 14 27 13 NA NA NA NA NA NA 5176 XM_044312420.1 27 2 14 0 0 O75923 0 Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1) Homo sapiens (Human) macrophage activation involved in immune response [GO:0002281]; membrane fusion [GO:0061025]; monocyte activation involved in immune response [GO:0002280]; negative regulation of phagocytosis [GO:0050765]; plasma membrane organization [GO:0007009]; plasma membrane repair [GO:0001778]; T-tubule organization [GO:0033292]; vesicle fusion [GO:0006906] GO:0001778; GO:0002280; GO:0002281; GO:0005509; GO:0005543; GO:0005544; GO:0005768; GO:0005769; GO:0005770; GO:0005886; GO:0006906; GO:0007009; GO:0030139; GO:0030315; GO:0030659; GO:0031410; GO:0033292; GO:0034451; GO:0042383; GO:0050765; GO:0061025; GO:0070062 5177 XM_029349272.2 0 0 0 0 191 Q9UHJ3 1.4e-82 Scm-like with four MBT domains protein 1 (hSFMBT) (Renal ubiquitous protein 1) Homo sapiens (Human) cell differentiation [GO:0030154]; chromatin organization [GO:0006325]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of muscle organ development [GO:0048635]; spermatogenesis [GO:0007283] GO:0003682; GO:0003714; GO:0005634; GO:0005654; GO:0006325; GO:0007283; GO:0030154; GO:0042393; GO:0045892; GO:0048635 5178 XM_044315163.1 4 0 0 0 13 P49642 8.88e-158 DNA primase small subunit (EC 2.7.7.102) (DNA primase 49 kDa subunit) (p49) Homo sapiens (Human) DNA replication initiation [GO:0006270]; DNA replication, synthesis of RNA primer [GO:0006269] GO:0000287; GO:0003896; GO:0005654; GO:0005658; GO:0006269; GO:0006270; GO:0008270; GO:0016020; GO:0032553 5179 XM_044322610.1 0 0 0 0 125 A0JMA8 5.59e-161 LisH domain-containing protein ARMC9 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cilium assembly [GO:0060271]; positive regulation of smoothened signaling pathway [GO:0045880] GO:0005737; GO:0005814; GO:0005929; GO:0036064; GO:0045880; GO:0060271; GO:0097542 5180 XM_029326990.2 311 178 110 170 217 Q8BYI6 6.11e-140 Lysophosphatidylcholine acyltransferase 2 (LPC acyltransferase 2) (LPCAT-2) (LysoPC acyltransferase 2) (EC 2.3.1.23) (1-acylglycerol-3-phosphate O-acyltransferase 11) (1-AGP acyltransferase 11) (1-AGPAT 11) (EC 2.3.1.51) (1-acylglycerophosphocholine O-acyltransferase) (1-alkenylglycerophosphocholine O-acyltransferase) (EC 2.3.1.25) (1-alkylglycerophosphocholine O-acetyltransferase) (EC 2.3.1.67) (Acetyl-CoA:lyso-platelet-activating factor acetyltransferase) (Acetyl-CoA:lyso-PAF acetyltransferase) (Lyso-PAF acetyltransferase) (LysoPAFAT) (Acyltransferase-like 1) Mus musculus (Mouse) membrane organization [GO:0061024]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; platelet activating factor biosynthetic process [GO:0006663] GO:0000139; GO:0003841; GO:0005509; GO:0005783; GO:0005789; GO:0005795; GO:0005811; GO:0005886; GO:0006663; GO:0016020; GO:0036151; GO:0047159; GO:0047184; GO:0047192; GO:0050200; GO:0061024 5181 XM_029354191.2 4294 3859 2561 2963 2594 NA NA NA NA NA NA 5182 XM_044327699.1 32 23 12 46 34 NA NA NA NA NA NA 5183 XM_029334829.2 477 144 168 126 277 NA NA NA NA NA NA 5184 XM_044308176.1 0 0 20 22 0 NA NA NA NA NA NA 5185 XM_029333249.2 81 0 35 0 0 Q16281 0 Cyclic nucleotide-gated cation channel alpha-3 (Cone photoreceptor cGMP-gated channel subunit alpha) (Cyclic nucleotide-gated channel alpha-3) (CNG channel alpha-3) (CNG-3) (CNG3) Homo sapiens (Human) cation transmembrane transport [GO:0098655]; cation transport [GO:0006812]; inorganic cation import across plasma membrane [GO:0098659]; response to cAMP [GO:0051591]; response to corticosteroid [GO:0031960]; response to magnesium ion [GO:0032026]; signal transduction [GO:0007165]; visual perception [GO:0007601] GO:0005222; GO:0005223; GO:0005737; GO:0005886; GO:0006812; GO:0007165; GO:0007601; GO:0008022; GO:0015276; GO:0017071; GO:0030425; GO:0030553; GO:0031960; GO:0032026; GO:0043194; GO:0043204; GO:0044877; GO:0051591; GO:0097386; GO:0098655; GO:0098659; GO:1902495 5186 XM_029335229.2 29 606 674 1732 1589 Q6GM82 2.08e-162 Alanine aminotransferase 2 (ALT2) (EC 2.6.1.2) (Glutamate pyruvate transaminase 2) (GPT 2) (Glutamic--alanine transaminase 2) (Glutamic--pyruvic transaminase 2) Xenopus laevis (African clawed frog) 2-oxoglutarate metabolic process [GO:0006103]; biosynthetic process [GO:0009058]; L-alanine catabolic process [GO:0042853]; L-alanine metabolic process [GO:0042851] GO:0004021; GO:0006103; GO:0009058; GO:0030170; GO:0042851; GO:0042853 5187 XM_044313205.1 261 55 0 0 0 NA NA NA NA NA NA 5188 XM_029337926.2 282 91 136 254 273 Q61712 3.69e-94 DnaJ homolog subfamily C member 1 (DnaJ protein homolog MTJ1) Mus musculus (Mouse) protein folding [GO:0006457]; regulation of protein secretion [GO:0050708]; regulation of translation [GO:0006417] GO:0003677; GO:0005634; GO:0005783; GO:0005788; GO:0005789; GO:0005886; GO:0006417; GO:0006457; GO:0012505; GO:0016020; GO:0031965; GO:0043022; GO:0050708; GO:0051087 5189 XM_044308973.1 8 0 0 2 8 NA NA NA NA NA NA 5190 XM_029329356.2 9 0 7 37 16 NA NA NA NA NA NA 5191 XM_044313634.1 13 0 4 0 5 NA NA NA NA NA NA 5192 XM_044322664.1 12 22 14 13 48 NA NA NA NA NA NA 5193 XM_029330069.2 31 0 0 0 0 Q14155 4.04e-152 Rho guanine nucleotide exchange factor 7 (Beta-Pix) (COOL-1) (PAK-interacting exchange factor beta) (p85) Homo sapiens (Human) ephrin receptor signaling pathway [GO:0048013]; focal adhesion assembly [GO:0048041]; Golgi organization [GO:0007030]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; negative regulation of microtubule nucleation [GO:1905833]; nervous system development [GO:0007399]; positive regulation of apoptotic process [GO:0043065]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of GTPase activity [GO:0043547]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of GTP binding [GO:1904424]; signal transduction [GO:0007165] GO:0001726; GO:0005085; GO:0005737; GO:0005813; GO:0005829; GO:0005925; GO:0005938; GO:0007030; GO:0007165; GO:0007399; GO:0010763; GO:0019901; GO:0030027; GO:0030032; GO:0032991; GO:0035556; GO:0043005; GO:0043015; GO:0043025; GO:0043065; GO:0043547; GO:0048013; GO:0048041; GO:0097431; GO:0098794; GO:1900026; GO:1904424; GO:1905833; GO:2000394 5194 XM_044310462.1 449 79 251 370 160 NA NA NA NA NA NA 5195 XM_044324516.1 388 105 194 212 437 NA NA NA NA NA NA 5196 XR_006391769.1 0 1 0 0 9 NA NA NA NA NA NA 5197 XM_044311595.1 0 17 0 2 0 NA NA NA NA NA NA 5198 XR_006398038.1 0 0 0 0 179 P46197 1.81e-139 Atrial natriuretic peptide receptor 2 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type B) (ANP-B) (ANPR-B) (NPR-B) (Guanylate cyclase B) (GC-B) Bos taurus (Bovine) activation of meiosis involved in egg activation [GO:0060466]; axonogenesis involved in innervation [GO:0060385]; blood circulation [GO:0008015]; blood vessel remodeling [GO:0001974]; c-di-GMP signaling [GO:0061939]; cellular response to cGMP [GO:0071321]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to peptide [GO:1901653]; cGMP biosynthetic process [GO:0006182]; chemical synaptic transmission [GO:0007268]; chondrocyte differentiation [GO:0002062]; chondrocyte proliferation [GO:0035988]; chromosome organization [GO:0051276]; collateral sprouting [GO:0048668]; cumulus cell differentiation [GO:0001549]; digestive tract morphogenesis [GO:0048546]; endochondral ossification [GO:0001958]; epidermal growth factor receptor signaling pathway [GO:0007173]; execution phase of apoptosis [GO:0097194]; female genitalia development [GO:0030540]; gastric emptying [GO:0035483]; genitalia morphogenesis [GO:0035112]; growth plate cartilage development [GO:0003417]; limb morphogenesis [GO:0035108]; lymph vessel development [GO:0001945]; MAPK cascade [GO:0000165]; meiotic cell cycle process involved in oocyte maturation [GO:1903537]; multicellular organism growth [GO:0035264]; negative regulation of meiotic cell cycle [GO:0051447]; negative regulation of oocyte maturation [GO:1900194]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; post-anal tail morphogenesis [GO:0036342]; protein phosphorylation [GO:0006468]; receptor guanylyl cyclase signaling pathway [GO:0007168]; response to fibroblast growth factor [GO:0071774]; response to luteinizing hormone [GO:0034699]; response to salt [GO:1902074]; sensory perception of sound [GO:0007605]; signal transduction [GO:0007165]; smooth muscle tissue development [GO:0048745]; spermatogenesis [GO:0007283]; startle response [GO:0001964]; vacuole organization [GO:0007033]; vascular wound healing [GO:0061042]; vasculogenesis [GO:0001570]; vestibulocochlear nerve maturation [GO:0021647]; white fat cell differentiation [GO:0050872] GO:0000165; GO:0001549; GO:0001570; GO:0001653; GO:0001945; GO:0001958; GO:0001964; GO:0001974; GO:0002062; GO:0003417; GO:0004383; GO:0004672; GO:0005524; GO:0005525; GO:0005634; GO:0005737; GO:0005886; GO:0005929; GO:0006182; GO:0006468; GO:0007033; GO:0007165; GO:0007168; GO:0007173; GO:0007268; GO:0007283; GO:0007605; GO:0008015; GO:0016941; GO:0017046; GO:0019228; GO:0021647; GO:0030540; GO:0034699; GO:0035108; GO:0035112; GO:0035264; GO:0035483; GO:0035988; GO:0036342; GO:0042802; GO:0043005; GO:0045202; GO:0048546; GO:0048668; GO:0048745; GO:0050872; GO:0051276; GO:0051402; GO:0051447; GO:0060385; GO:0060466; GO:0061042; GO:0061939; GO:0071321; GO:0071774; GO:0097011; GO:0097194; GO:1900194; GO:1901653; GO:1902074; GO:1903537 5199 XR_006398038.1 0 0 0 0 179 P46197 9.14e-23 Atrial natriuretic peptide receptor 2 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type B) (ANP-B) (ANPR-B) (NPR-B) (Guanylate cyclase B) (GC-B) Bos taurus (Bovine) activation of meiosis involved in egg activation [GO:0060466]; axonogenesis involved in innervation [GO:0060385]; blood circulation [GO:0008015]; blood vessel remodeling [GO:0001974]; c-di-GMP signaling [GO:0061939]; cellular response to cGMP [GO:0071321]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to peptide [GO:1901653]; cGMP biosynthetic process [GO:0006182]; chemical synaptic transmission [GO:0007268]; chondrocyte differentiation [GO:0002062]; chondrocyte proliferation [GO:0035988]; chromosome organization [GO:0051276]; collateral sprouting [GO:0048668]; cumulus cell differentiation [GO:0001549]; digestive tract morphogenesis [GO:0048546]; endochondral ossification [GO:0001958]; epidermal growth factor receptor signaling pathway [GO:0007173]; execution phase of apoptosis [GO:0097194]; female genitalia development [GO:0030540]; gastric emptying [GO:0035483]; genitalia morphogenesis [GO:0035112]; growth plate cartilage development [GO:0003417]; limb morphogenesis [GO:0035108]; lymph vessel development [GO:0001945]; MAPK cascade [GO:0000165]; meiotic cell cycle process involved in oocyte maturation [GO:1903537]; multicellular organism growth [GO:0035264]; negative regulation of meiotic cell cycle [GO:0051447]; negative regulation of oocyte maturation [GO:1900194]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; post-anal tail morphogenesis [GO:0036342]; protein phosphorylation [GO:0006468]; receptor guanylyl cyclase signaling pathway [GO:0007168]; response to fibroblast growth factor [GO:0071774]; response to luteinizing hormone [GO:0034699]; response to salt [GO:1902074]; sensory perception of sound [GO:0007605]; signal transduction [GO:0007165]; smooth muscle tissue development [GO:0048745]; spermatogenesis [GO:0007283]; startle response [GO:0001964]; vacuole organization [GO:0007033]; vascular wound healing [GO:0061042]; vasculogenesis [GO:0001570]; vestibulocochlear nerve maturation [GO:0021647]; white fat cell differentiation [GO:0050872] GO:0000165; GO:0001549; GO:0001570; GO:0001653; GO:0001945; GO:0001958; GO:0001964; GO:0001974; GO:0002062; GO:0003417; GO:0004383; GO:0004672; GO:0005524; GO:0005525; GO:0005634; GO:0005737; GO:0005886; GO:0005929; GO:0006182; GO:0006468; GO:0007033; GO:0007165; GO:0007168; GO:0007173; GO:0007268; GO:0007283; GO:0007605; GO:0008015; GO:0016941; GO:0017046; GO:0019228; GO:0021647; GO:0030540; GO:0034699; GO:0035108; GO:0035112; GO:0035264; GO:0035483; GO:0035988; GO:0036342; GO:0042802; GO:0043005; GO:0045202; GO:0048546; GO:0048668; GO:0048745; GO:0050872; GO:0051276; GO:0051402; GO:0051447; GO:0060385; GO:0060466; GO:0061042; GO:0061939; GO:0071321; GO:0071774; GO:0097011; GO:0097194; GO:1900194; GO:1901653; GO:1902074; GO:1903537 5200 XM_029329919.2 4694 4953 3034 3865 2878 Q9BU79 2.56e-31 Transmembrane protein 243 (MDR1- and mitochondrial taxol resistance-associated protein) (MM-TRAG) Homo sapiens (Human) NA GO:0016020 5201 XM_029335492.2 40 44 19 49 91 Q9UJV9 2.9e-91 Probable ATP-dependent RNA helicase DDX41 (EC 3.6.4.13) (DEAD box protein 41) (DEAD box protein abstrakt homolog) Homo sapiens (Human) apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005681; GO:0005829; GO:0006915; GO:0008283; GO:0016020; GO:0016887; GO:0030154; GO:0046872; GO:0071013 5202 XM_029347923.2 709 1197 1071 1754 1264 Q5PRC7 2.41e-51 SOSS complex subunit B2 (Nucleic acid-binding protein 1) (Oligonucleotide/oligosaccharide-binding fold-containing protein 2A) (Sensor of single-strand DNA complex subunit B2) (Sensor of ssDNA subunit B2) (SOSS-B2) (Single-stranded DNA-binding protein 2) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; mitotic G2/M transition checkpoint [GO:0044818]; response to ionizing radiation [GO:0010212] GO:0000724; GO:0003677; GO:0003697; GO:0005634; GO:0006281; GO:0006974; GO:0010212; GO:0044818; GO:0070876 5203 XM_029337623.2 0 0 0 0 36 NA NA NA NA NA NA 5204 XM_044322175.1 875 297 404 581 571 P22045 8.4e-42 9,11-endoperoxide prostaglandin H2 reductase (EC 1.1.1.-) (Prostaglandin F2-alpha synthase) Leishmania major prostaglandin biosynthetic process [GO:0001516] GO:0000166; GO:0001516; GO:0005737; GO:0036130 5205 XR_006391566.1 6 8 0 2 10 NA NA NA NA NA NA 5206 XM_044317391.1 4126 2077 6140 5218 5884 NA NA NA NA NA NA 5207 XM_029346399.2 74 235 0 259 15 Q5TD94 1.2e-141 Radial spoke head protein 4 homolog A (Radial spoke head-like protein 3) Homo sapiens (Human) axoneme assembly [GO:0035082]; cilium movement [GO:0003341]; cilium movement involved in cell motility [GO:0060294]; maintenance of ciliary planar beating movement pattern [GO:0120221]; radial spoke assembly [GO:0062177] GO:0001534; GO:0001535; GO:0003341; GO:0005654; GO:0005730; GO:0005930; GO:0031514; GO:0035082; GO:0060294; GO:0062177; GO:0120221 5208 XM_044313992.1 206 90 33 8 8 NA NA NA NA NA NA 5209 XM_044307027.1 8 0 0 0 13 P0DP43 1.48e-35 Cation channel sperm-associated auxiliary subunit epsilon (CatSper-epsilon) (CatSperepsilon) (C1orf101-like protein) Mus musculus (Mouse) flagellated sperm motility [GO:0030317]; sperm capacitation [GO:0048240] GO:0030317; GO:0036128; GO:0048240; GO:0097228 5210 XM_044324454.1 0 11 0 20 51 NA NA NA NA NA NA 5211 XM_029329274.2 2700 1799 1447 3380 2185 P48509 1.01e-39 CD151 antigen (GP27) (Membrane glycoprotein SFA-1) (Platelet-endothelial tetraspan antigen 3) (PETA-3) (Tetraspanin-24) (Tspan-24) (CD antigen CD151) Homo sapiens (Human) cell adhesion [GO:0007155]; cell migration [GO:0016477]; positive regulation of cell migration [GO:0030335]; positive regulation of endocytosis [GO:0045807]; T cell proliferation [GO:0042098]; wound healing, spreading of cells [GO:0044319] GO:0005178; GO:0005604; GO:0005829; GO:0005886; GO:0005925; GO:0007155; GO:0009986; GO:0016020; GO:0016477; GO:0030335; GO:0042098; GO:0044319; GO:0045807 5212 XM_044313519.1 0 0 5 0 7 NA NA NA NA NA NA 5213 XM_029340201.2 0 0 0 0 75 NA NA NA NA NA NA 5214 XM_029333774.2 101 0 0 14 9 Q7TN88 3.23e-68 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 5215 XM_029333774.2 101 0 0 14 9 Q7TN88 3.16e-49 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 5216 XM_044309742.1 24 11 7 4 39 NA NA NA NA NA NA 5217 XM_029326246.2 30 2 0 4 36 NA NA NA NA NA NA 5218 XM_029352169.2 18 13 8 25 29 Q8N5I4 1.03e-76 Dehydrogenase/reductase SDR family member on chromosome X (EC 1.1.-.-) (DHRSXY) (Short chain dehydrogenase/reductase family 46C member 1) (Short chain dehydrogenase/reductase family 7C member 6) Homo sapiens (Human) positive regulation of autophagy [GO:0010508] GO:0005576; GO:0010508; GO:0016491 5219 XM_029337906.2 1090 463 1080 2141 1404 NA NA NA NA NA NA 5220 XM_029338982.2 755 29 0 59 0 Q8HYJ7 8.39e-22 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5 (EC 2.4.1.152) (3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT5) (EC 2.4.1.65) (Fucosyltransferase 5) (Fucosyltransferase V) (Fuc-TV) (FucT-V) (Galactoside 3-L-fucosyltransferase) Gorilla gorilla gorilla (Western lowland gorilla) ceramide metabolic process [GO:0006672]; fucosylation [GO:0036065]; oligosaccharide metabolic process [GO:0009311]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493] GO:0006487; GO:0006493; GO:0006672; GO:0009311; GO:0017060; GO:0017083; GO:0032580; GO:0036065; GO:0046920 5221 XM_029324555.2 81 51 37 68 85 Q8BL86 2.76e-83 Acyl-coenzyme A thioesterase MBLAC2 (Acyl-CoA thioesterase MBLAC2) (EC 3.1.2.2) (Beta-lactamase MBLAC2) (EC 3.5.2.6) (Metallo-beta-lactamase domain-containing protein 2) (Palmitoyl-coenzyme A thioesterase MBLAC2) Mus musculus (Mouse) fatty acid metabolic process [GO:0006631] GO:0005789; GO:0005886; GO:0006631; GO:0008800; GO:0016290; GO:0046872; GO:0102991 5222 XM_029351056.2 10 0 0 3 30 NA NA NA NA NA NA 5223 XM_029329248.2 2 30 20 54 21 Q8C627 2.71e-63 Protein FAM221B Mus musculus (Mouse) NA NA 5224 XM_029324691.2 0 0 0 0 62 Q9W4S1 4.08e-31 Glutaredoxin domain-containing cysteine-rich protein CG12206 Drosophila melanogaster (Fruit fly) sensory perception of sound [GO:0007605] GO:0007605 5225 XM_029344700.2 2024 1796 1120 1720 1112 P07090 2.31e-67 Calretinin (CR) Gallus gallus (Chicken) regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of long-term synaptic potentiation [GO:1900271]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509] GO:0005509; GO:0005634; GO:0005829; GO:0030425; GO:0043005; GO:0043195; GO:0045202; GO:0051480; GO:0099509; GO:1900271 5226 XM_029344700.2 2024 1796 1120 1720 1112 P07090 8.63e-23 Calretinin (CR) Gallus gallus (Chicken) regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of long-term synaptic potentiation [GO:1900271]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509] GO:0005509; GO:0005634; GO:0005829; GO:0030425; GO:0043005; GO:0043195; GO:0045202; GO:0051480; GO:0099509; GO:1900271 5227 XR_006397343.1 17 5 0 0 1 NA NA NA NA NA NA 5228 XM_044313599.1 126 58 120 141 237 NA NA NA NA NA NA 5229 XM_029325103.1 5 9 5 4 15 NA NA NA NA NA NA 5230 XM_044326905.1 1 55 112 14 89 NA NA NA NA NA NA 5231 XM_044314477.1 0 40 55 0 52 Q9NZJ4 0 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 5232 XM_044314477.1 0 40 55 0 52 Q9NZJ4 4.79e-42 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 5233 XM_029336308.2 901 724 444 767 769 Q80W31 3e-70 Zinc finger protein 569 (Mszf21) (Zinc finger protein 74) (Zfp-74) Mus musculus (Mouse) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 5234 XM_029336308.2 901 724 444 767 769 Q80W31 7.32e-48 Zinc finger protein 569 (Mszf21) (Zinc finger protein 74) (Zfp-74) Mus musculus (Mouse) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 5235 XM_029336308.2 901 724 444 767 769 Q80W31 1.23e-30 Zinc finger protein 569 (Mszf21) (Zinc finger protein 74) (Zfp-74) Mus musculus (Mouse) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 5236 XM_029330235.2 911 997 570 913 1025 Q6GLE8 6.93e-37 Leucine-rich repeat-containing protein 28 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA NA 5237 XM_029341826.2 96 44 34 119 172 NA NA NA NA NA NA 5238 XR_006391540.1 38 0 0 0 38 NA NA NA NA NA NA 5239 XM_044312402.1 4 7 1 12 2 NA NA NA NA NA NA 5240 XM_044316572.1 5 4 54 109 55 NA NA NA NA NA NA 5241 XM_044328904.1 73 24 67 69 96 NA NA NA NA NA NA 5242 XM_029324585.2 28 17 10 22 20 Q0VCM2 2.68e-48 Transmembrane protein 187 Bos taurus (Bovine) NA GO:0016020; GO:0030133 5243 XM_029349284.2 0 89 80 109 58 P57788 7.1e-43 Monocarboxylate transporter 4 (MCT 4) (Solute carrier family 16 member 3) Gallus gallus (Chicken) lactate transmembrane transport [GO:0035873]; pyruvate transmembrane transport [GO:1901475] GO:0005886; GO:0015650; GO:0016323; GO:0035873; GO:0050833; GO:1901475 5244 XM_044321690.1 1438 587 524 740 524 P15848 1.52e-154 Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S) Homo sapiens (Human) autophagy [GO:0006914]; central nervous system development [GO:0007417]; colon epithelial cell migration [GO:0061580]; lysosomal transport [GO:0007041]; lysosome organization [GO:0007040]; positive regulation of neuron projection development [GO:0010976]; regulation of epithelial cell migration [GO:0010632]; response to estrogen [GO:0043627]; response to methylmercury [GO:0051597]; response to nutrient [GO:0007584]; response to pH [GO:0009268] GO:0003943; GO:0004065; GO:0005576; GO:0005739; GO:0005764; GO:0005788; GO:0005791; GO:0005794; GO:0006914; GO:0007040; GO:0007041; GO:0007417; GO:0007584; GO:0009268; GO:0009986; GO:0010632; GO:0010976; GO:0035578; GO:0043202; GO:0043627; GO:0046872; GO:0051597; GO:0061580; GO:0070062; GO:1904813 5245 XM_044320795.1 1 0 0 0 27 NA NA NA NA NA NA 5246 XM_044312536.1 7 0 0 2 0 NA NA NA NA NA NA 5247 XM_029352129.2 95 181 293 138 290 Q9H3S4 2.52e-51 Thiamin pyrophosphokinase 1 (hTPK1) (EC 2.7.6.2) (Placental protein 20) (PP20) (Thiamine pyrophosphokinase 1) Homo sapiens (Human) phosphorylation [GO:0016310]; thiamine diphosphate biosynthetic process [GO:0009229]; thiamine metabolic process [GO:0006772] GO:0004788; GO:0005524; GO:0005829; GO:0006772; GO:0009229; GO:0016301; GO:0016310; GO:0030975; GO:0042802 5248 XM_029355459.2 689 324 423 559 823 Q9DBF7 9.09e-39 Pre-mRNA-splicing factor CWC25 homolog (Coiled-coil domain-containing protein 49) (Spliceosome-associated protein homolog CWC25) Mus musculus (Mouse) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0005634; GO:0005684; GO:0016607; GO:0071006 5249 XM_044313664.1 104 20 32 109 48 Q96P20 3e-41 NACHT, LRR and PYD domains-containing protein 3 (EC 3.6.4.-) (Angiotensin/vasopressin receptor AII/AVP-like) (Caterpiller protein 1.1) (CLR1.1) (Cold-induced autoinflammatory syndrome 1 protein) (Cryopyrin) (PYRIN-containing APAF1-like protein 1) Homo sapiens (Human) apoptotic process [GO:0006915]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to virus [GO:0098586]; defense response [GO:0006952]; detection of biotic stimulus [GO:0009595]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; NLRP3 inflammasome complex assembly [GO:0044546]; osmosensory signaling pathway [GO:0007231]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type 2 immune response [GO:0002830]; protein homooligomerization [GO:0051260]; pyroptosis [GO:0070269]; regulation of inflammatory response [GO:0050727]; signal transduction [GO:0007165] GO:0000139; GO:0002221; GO:0002674; GO:0002830; GO:0005524; GO:0005576; GO:0005634; GO:0005737; GO:0005739; GO:0005783; GO:0005815; GO:0005829; GO:0006915; GO:0006952; GO:0006954; GO:0007165; GO:0007231; GO:0009595; GO:0016020; GO:0016887; GO:0031021; GO:0032088; GO:0032691; GO:0032731; GO:0032753; GO:0035591; GO:0042802; GO:0042834; GO:0043280; GO:0043531; GO:0043565; GO:0044546; GO:0045087; GO:0045630; GO:0045944; GO:0050727; GO:0050728; GO:0050729; GO:0051092; GO:0051260; GO:0070269; GO:0070273; GO:0071222; GO:0072559; GO:0098586; GO:0140297; GO:0140299; GO:1901223; GO:1901981; GO:2000553 5250 XM_044313212.1 69 5 27 15 49 Q866A2 2.54e-54 Neuronal acetylcholine receptor subunit alpha-7 Macaca mulatta (Rhesus macaque) associative learning [GO:0008306]; B cell activation [GO:0042113]; behavioral response to ethanol [GO:0048149]; behavioral response to nicotine [GO:0035095]; calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; cognition [GO:0050890]; dendrite arborization [GO:0140059]; dendritic spine organization [GO:0097061]; endocytosis [GO:0006897]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; generation of ovulation cycle rhythm [GO:0060112]; ion transmembrane transport [GO:0034220]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of tumor necrosis factor production [GO:0032720]; nervous system process [GO:0050877]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of CoA-transferase activity [GO:1905920]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure [GO:0001988]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; regulation of amyloid fibril formation [GO:1905906]; regulation of membrane potential [GO:0042391]; regulation of neuron death [GO:1901214]; regulation of norepinephrine secretion [GO:0014061]; regulation of synaptic transmission, dopaminergic [GO:0032225]; response to amyloid-beta [GO:1904645]; response to cold [GO:0009409]; response to food [GO:0032094]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; sensory processing [GO:0050893]; short-term memory [GO:0007614]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271]; T cell activation [GO:0042110] GO:0001540; GO:0001666; GO:0001933; GO:0001988; GO:0005231; GO:0005886; GO:0005892; GO:0006816; GO:0006874; GO:0006897; GO:0007165; GO:0007268; GO:0007271; GO:0007614; GO:0008284; GO:0008306; GO:0009409; GO:0009897; GO:0014061; GO:0015464; GO:0015643; GO:0016324; GO:0017081; GO:0022848; GO:0030317; GO:0030594; GO:0030673; GO:0032094; GO:0032225; GO:0032691; GO:0032715; GO:0032720; GO:0033138; GO:0034220; GO:0035094; GO:0035095; GO:0042110; GO:0042113; GO:0042166; GO:0042391; GO:0042734; GO:0042803; GO:0043005; GO:0043410; GO:0045202; GO:0045766; GO:0048149; GO:0050728; GO:0050877; GO:0050890; GO:0050893; GO:0051649; GO:0060112; GO:0070374; GO:0097061; GO:0098839; GO:0098978; GO:0098981; GO:0140059; GO:1900273; GO:1901214; GO:1902004; GO:1904315; GO:1904645; GO:1905906; GO:1905920; GO:2000463 5251 XR_006394154.1 1 1 1274 1 1 NA NA NA NA NA NA 5252 XM_029342184.2 5788 5595 4009 4303 3360 Q9CQ92 8.66e-29 Mitochondrial fission 1 protein (FIS1 homolog) (Tetratricopeptide repeat protein 11) (TPR repeat protein 11) Mus musculus (Mouse) autophagy of mitochondrion [GO:0000422]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular response to peptide [GO:1901653]; mitochondrial fission [GO:0000266]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; mitochondrial fusion [GO:0008053]; mitochondrion morphogenesis [GO:0070584]; negative regulation of ATP metabolic process [GO:1903579]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; negative regulation of fatty acid transport [GO:2000192]; peroxisome fission [GO:0016559]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein targeting to membrane [GO:0090314]; protein targeting to mitochondrion [GO:0006626]; regulation of mitochondrion organization [GO:0010821]; release of cytochrome c from mitochondria [GO:0001836]; response to endoplasmic reticulum stress [GO:0034976] GO:0000266; GO:0000422; GO:0001836; GO:0005739; GO:0005741; GO:0005777; GO:0005778; GO:0005783; GO:0006626; GO:0007204; GO:0008053; GO:0008289; GO:0010821; GO:0016559; GO:0032471; GO:0032991; GO:0034976; GO:0035584; GO:0042802; GO:0043280; GO:0043525; GO:0043653; GO:0044877; GO:0051561; GO:0060090; GO:0070584; GO:0090141; GO:0090314; GO:1901653; GO:1903579; GO:2000192; GO:2001244 5253 XM_044311642.1 222 83 35 193 364 B8VIU6 3.44e-67 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 5254 XM_044311642.1 222 83 35 193 364 B8VIU6 1.01e-63 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 5255 XM_044311642.1 222 83 35 193 364 B8VIU6 1.45e-62 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 5256 XM_044318884.1 2015 1762 936 1899 1625 NA NA NA NA NA NA 5257 XR_006391784.1 4 62 45 0 0 NA NA NA NA NA NA 5258 XM_029338500.2 704 710 700 538 470 Q95JY5 5.34e-32 Sterile alpha motif domain-containing protein 15 (SAM domain-containing protein 15) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA NA 5259 XM_044310992.1 1450 239 541 475 311 NA NA NA NA NA NA 5260 XM_044323643.1 2 41 2 4 11 P0CV72 9.83e-33 Secreted RxLR effector protein 161 Plasmopara viticola (Downy mildew of grapevine) (Botrytis viticola) NA GO:0005576; GO:0042025 5261 XM_029345395.2 2 2 3 16 5 NA NA NA NA NA NA 5262 XM_029332721.2 0 8 0 25 4 NA NA NA NA NA NA 5263 XM_029357302.2 411 554 201 520 420 Q63955 3.44e-81 POU domain, class 4, transcription factor 3 (Brain-specific homeobox/POU domain protein 3C) (Brain-3C) (Brn-3C) (Brn-3.1) Mus musculus (Mouse) axon extension [GO:0048675]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear development [GO:0048839]; inner ear morphogenesis [GO:0042472]; inner ear receptor cell differentiation [GO:0060113]; neuromuscular process controlling balance [GO:0050885]; neuron apoptotic process [GO:0051402]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; retinal ganglion cell axon guidance [GO:0031290]; sensory perception of sound [GO:0007605]; vestibulocochlear nerve development [GO:0021562] GO:0000978; GO:0000981; GO:0001228; GO:0003700; GO:0005634; GO:0005654; GO:0005667; GO:0005737; GO:0006357; GO:0007605; GO:0021562; GO:0031290; GO:0042472; GO:0042491; GO:0043565; GO:0045944; GO:0048675; GO:0048839; GO:0050885; GO:0051402; GO:0060113; GO:1990837 5264 XM_029344473.2 1373 922 373 1052 760 A6H8T7 2.31e-146 Cytosolic carboxypeptidase 2 (EC 3.4.17.-) (ATP/GTP-binding protein-like 2) (Protein deglutamylase CCP2) (Testis-expressed protein 25) Danio rerio (Zebrafish) (Brachydanio rerio) protein side chain deglutamylation [GO:0035610]; proteolysis [GO:0006508] GO:0004181; GO:0005814; GO:0005829; GO:0006508; GO:0008270; GO:0035610; GO:0036064 5265 XM_044311302.1 0 36 0 85 11 Q91W78 5.04e-34 U6 snRNA phosphodiesterase 1 (3'-5' RNA exonuclease USB1) (EC 4.6.1.-) Mus musculus (Mouse) RNA splicing [GO:0008380]; snRNA 3'-end processing [GO:0034472]; U6 snRNA 3'-end processing [GO:0034477] GO:0000175; GO:0005634; GO:0005654; GO:0008380; GO:0016829; GO:0034472; GO:0034477; GO:0045171; GO:1990838 5266 XM_044313368.1 47 35 376 80 226 NA NA NA NA NA NA 5267 XM_029327018.2 42 78 11 16 63 Q5BKQ4 1.42e-59 Inactive pancreatic lipase-related protein 1 (PL-RP1) Mus musculus (Mouse) lipid metabolic process [GO:0006629] GO:0004806; GO:0005509; GO:0005615; GO:0006629; GO:0016298 5268 XR_003826620.2 579 1346 225 778 256 NA NA NA NA NA NA 5269 XM_029329733.2 488 275 223 373 269 Q9I8C7 1.36e-77 Neuronal acetylcholine receptor subunit alpha-10 (Alpha 10 nAChR) (Nicotinic acetylcholine receptor subunit alpha-10) (NACHR alpha-10) Gallus gallus (Chicken) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; response to auditory stimulus [GO:0010996]; signal transduction [GO:0007165] GO:0004888; GO:0005231; GO:0005262; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0010996; GO:0022848; GO:0030594; GO:0034220; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051899; GO:1904315 5270 XM_029344140.2 1014 1067 855 939 744 A7S1H9 8.87e-27 Succinate dehydrogenase assembly factor 3, mitochondrial (SDH assembly factor 3) (SDHAF3) Nematostella vectensis (Starlet sea anemone) mitochondrial respiratory chain complex II assembly [GO:0034553]; succinate metabolic process [GO:0006105] GO:0005758; GO:0005759; GO:0006105; GO:0034553 5271 XM_044326577.1 156 42 69 66 216 Q4R3S3 4.31e-45 Ankyrin repeat domain-containing protein 7 Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA NA 5272 XM_044322067.1 129 77 106 143 44 Q99570 0 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 5273 XM_029343251.2 72 170 49 162 94 Q5F433 2.28e-30 PRA1 family protein 3 (ADP-ribosylation factor-like protein 6-interacting protein 5) (ARL-6-interacting protein 5) (Aip-5) Gallus gallus (Chicken) cellular response to organic cyclic compound [GO:0071407]; glutathione metabolic process [GO:0006749]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; L-glutamate import across plasma membrane [GO:0098712]; L-glutamate transmembrane transport [GO:0015813]; learning or memory [GO:0007611]; negative regulation of L-glutamate import across plasma membrane [GO:0002037]; negative regulation of mitochondrial membrane potential [GO:0010917]; negative regulation of transport [GO:0051051]; neuron death in response to oxidative stress [GO:0036475]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of stress-activated MAPK cascade [GO:0032874]; protein localization to plasma membrane [GO:0072659]; protein transport [GO:0015031] GO:0002037; GO:0005789; GO:0005856; GO:0005886; GO:0006749; GO:0007611; GO:0008631; GO:0010917; GO:0015031; GO:0015813; GO:0016020; GO:0032874; GO:0036475; GO:0043065; GO:0043280; GO:0051051; GO:0071407; GO:0072659; GO:0098712; GO:0099523 5274 XM_044324493.1 1 1 1 60 11 NA NA NA NA NA NA 5275 XR_006394635.1 58 223 14 208 19 NA NA NA NA NA NA 5276 XR_006394475.1 0 0 4 5 32 NA NA NA NA NA NA 5277 XM_029335876.2 6332 4102 2110 5284 3452 NA NA NA NA NA NA 5278 XM_029353846.2 41 178 369 331 170 A6H7G2 2.14e-43 Drebrin-like protein Bos taurus (Bovine) adaptive immune response [GO:0002250]; endocytosis [GO:0006897]; neuron projection morphogenesis [GO:0048812]; podosome assembly [GO:0071800]; positive regulation of axon extension [GO:0045773]; positive regulation of dendritic spine morphogenesis [GO:0061003]; postsynaptic actin cytoskeleton organization [GO:0098974]; regulation of actin filament polymerization [GO:0030833]; synapse assembly [GO:0007416] GO:0000139; GO:0001726; GO:0002102; GO:0002250; GO:0005769; GO:0005829; GO:0006897; GO:0007416; GO:0014069; GO:0030027; GO:0030425; GO:0030427; GO:0030665; GO:0030833; GO:0030864; GO:0043204; GO:0045211; GO:0045773; GO:0048812; GO:0051015; GO:0061003; GO:0070161; GO:0071800; GO:0098974 5279 XM_029353846.2 41 178 369 331 170 A6H7G2 2.64e-22 Drebrin-like protein Bos taurus (Bovine) adaptive immune response [GO:0002250]; endocytosis [GO:0006897]; neuron projection morphogenesis [GO:0048812]; podosome assembly [GO:0071800]; positive regulation of axon extension [GO:0045773]; positive regulation of dendritic spine morphogenesis [GO:0061003]; postsynaptic actin cytoskeleton organization [GO:0098974]; regulation of actin filament polymerization [GO:0030833]; synapse assembly [GO:0007416] GO:0000139; GO:0001726; GO:0002102; GO:0002250; GO:0005769; GO:0005829; GO:0006897; GO:0007416; GO:0014069; GO:0030027; GO:0030425; GO:0030427; GO:0030665; GO:0030833; GO:0030864; GO:0043204; GO:0045211; GO:0045773; GO:0048812; GO:0051015; GO:0061003; GO:0070161; GO:0071800; GO:0098974 5280 XR_006395474.1 234 258 14 511 181 NA NA NA NA NA NA 5281 XM_029336451.2 395 512 306 432 498 Q15546 1.51e-53 Monocyte to macrophage differentiation factor (Progestin and adipoQ receptor family member 11) (Progestin and adipoQ receptor family member XI) Homo sapiens (Human) cytolysis [GO:0019835]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of protein kinase activity [GO:0045860]; regulation of protein localization [GO:0032880] GO:0004672; GO:0005765; GO:0005794; GO:0005886; GO:0016020; GO:0019835; GO:0031902; GO:0032880; GO:0038023; GO:0045666; GO:0045860 5282 XM_044312733.1 8764 8357 6219 11402 8290 Q66HG5 0 Transmembrane 9 superfamily member 2 Rattus norvegicus (Rat) ceramide metabolic process [GO:0006672]; glycosphingolipid biosynthetic process [GO:0006688]; protein localization to membrane [GO:0072657]; regulation of heparan sulfate proteoglycan biosynthetic process [GO:0010908] GO:0005794; GO:0005856; GO:0006672; GO:0006688; GO:0010008; GO:0010908; GO:0016020; GO:0072657 5283 XR_006391549.1 107 76 45 4 103 NA NA NA NA NA NA 5284 XM_044317493.1 88 77 65 209 494 Q8R151 0 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 5285 XM_044317493.1 88 77 65 209 494 Q8R151 2.96e-87 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 5286 XM_044323241.1 0 0 0 0 14 NA NA NA NA NA NA 5287 XM_044310684.1 331 427 173 381 241 Q96SL4 1.21e-48 Glutathione peroxidase 7 (GPx-7) (GSHPx-7) (EC 1.11.1.9) (CL683) Homo sapiens (Human) cellular response to oxidative stress [GO:0034599] GO:0004096; GO:0004601; GO:0004602; GO:0005576; GO:0005783; GO:0005788; GO:0034599 5288 XM_029342486.2 1391 344 360 2729 780 NA NA NA NA NA NA 5289 XM_044316394.1 9 5 10 56 0 NA NA NA NA NA NA 5290 XM_029349175.2 382 253 127 426 961 NA NA NA NA NA NA 5291 XM_029353820.2 960 389 514 1166 1496 NA NA NA NA NA NA 5292 XM_044308596.1 6 0 3 0 9 NA NA NA NA NA NA 5293 XM_029357749.2 0 0 0 0 45 P52483 5.24e-96 Ubiquitin-conjugating enzyme E2 E3 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme E3) (UbcM2) (Ubiquitin carrier protein E3) (Ubiquitin-conjugating enzyme E2-23 kDa) (Ubiquitin-protein ligase E3) Mus musculus (Mouse) protein K11-linked ubiquitination [GO:0070979]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209] GO:0000209; GO:0004842; GO:0005524; GO:0005634; GO:0005737; GO:0061631; GO:0070534; GO:0070936; GO:0070979 5294 XM_044323286.1 19 14 60 65 29 Q05360 6.49e-161 Protein white Lucilia cuprina (Green bottle fly) (Australian sheep blowfly) NA GO:0005524; GO:0016020; GO:0016887; GO:0031409; GO:0140359 5295 XM_029358036.2 587 467 255 368 358 Q8Q0U0 3.36e-21 Putative ankyrin repeat protein MM_0045 Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia) NA NA 5296 XM_029345460.2 29 0 0 15 0 Q8N2E2 1.55e-39 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 5297 XM_029345460.2 29 0 0 15 0 Q8N2E2 9.39e-38 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 5298 XM_029345460.2 29 0 0 15 0 Q8N2E2 1.67e-36 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 5299 XM_029345460.2 29 0 0 15 0 Q8N2E2 5.22e-35 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 5300 XM_029345460.2 29 0 0 15 0 Q8N2E2 6.14e-32 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 5301 XM_029345460.2 29 0 0 15 0 Q8N2E2 4.48e-25 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 5302 XM_029356224.2 410 199 134 399 631 Q4R4C7 3.2e-38 Zinc finger protein 14 Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) regulation of DNA-templated transcription [GO:0006355] GO:0003677; GO:0005634; GO:0006355; GO:0046872 5303 XM_029356224.2 410 199 134 399 631 Q4R4C7 6.56e-33 Zinc finger protein 14 Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) regulation of DNA-templated transcription [GO:0006355] GO:0003677; GO:0005634; GO:0006355; GO:0046872 5304 XM_029356224.2 410 199 134 399 631 Q4R4C7 7.97e-31 Zinc finger protein 14 Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) regulation of DNA-templated transcription [GO:0006355] GO:0003677; GO:0005634; GO:0006355; GO:0046872 5305 XM_029356224.2 410 199 134 399 631 Q4R4C7 6.01e-28 Zinc finger protein 14 Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) regulation of DNA-templated transcription [GO:0006355] GO:0003677; GO:0005634; GO:0006355; GO:0046872 5306 XM_029356224.2 410 199 134 399 631 Q4R4C7 5.71e-27 Zinc finger protein 14 Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) regulation of DNA-templated transcription [GO:0006355] GO:0003677; GO:0005634; GO:0006355; GO:0046872 5307 XM_029356224.2 410 199 134 399 631 Q4R4C7 2.32e-23 Zinc finger protein 14 Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) regulation of DNA-templated transcription [GO:0006355] GO:0003677; GO:0005634; GO:0006355; GO:0046872 5308 XM_029356224.2 410 199 134 399 631 Q4R4C7 9.63e-23 Zinc finger protein 14 Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) regulation of DNA-templated transcription [GO:0006355] GO:0003677; GO:0005634; GO:0006355; GO:0046872 5309 XM_044324395.1 813 36 364 458 729 Q9UPV0 2.77e-35 Centrosomal protein of 164 kDa (Cep164) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; cilium assembly [GO:0060271]; DNA repair [GO:0006281] GO:0005615; GO:0005654; GO:0005813; GO:0005814; GO:0005829; GO:0006281; GO:0007049; GO:0051301; GO:0060271; GO:0097539 5310 XM_029357776.2 198 15 0 454 0 O46606 6.96e-126 Phospholipase DDHD1 (EC 3.1.1.111) (EC 3.1.1.32) (DDHD domain-containing protein 1) (Phosphatidic acid-preferring phospholipase A1) (PA-PLA1) (EC 3.1.1.118) (Phospholipid sn-1 acylhydrolase) Bos taurus (Bovine) lipid metabolic process [GO:0006629] GO:0004620; GO:0005737; GO:0006629; GO:0008970; GO:0046872 5311 XR_006395543.1 57 32 22 25 89 NA NA NA NA NA NA 5312 XM_029339556.2 27 12 0 0 92 NA NA NA NA NA NA 5313 XM_044328198.1 161 209 240 166 382 NA NA NA NA NA NA 5314 XM_029333326.2 0 0 21 36 21 NA NA NA NA NA NA 5315 XM_029351559.2 245 0 66 39 109 Q6T938 5.08e-79 Acidic fibroblast growth factor intracellular-binding protein B (aFGF intracellular-binding protein B) (FGF-1 intracellular-binding protein B) Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; Kupffer's vesicle development [GO:0070121] GO:0005634; GO:0007368; GO:0012505; GO:0016020; GO:0017134; GO:0060026; GO:0060271; GO:0070121 5316 XM_044320200.1 66 60 40 80 123 E9PVD1 5.36e-70 Coiled-coil domain-containing protein 62 Mus musculus (Mouse) blastocyst hatching [GO:0001835]; cellular response to estradiol stimulus [GO:0071392]; positive regulation of transcription by RNA polymerase II [GO:0045944]; spermatid development [GO:0007286] GO:0001669; GO:0001835; GO:0005634; GO:0005654; GO:0005886; GO:0007286; GO:0030331; GO:0030374; GO:0045944; GO:0071392 5317 XM_044316234.1 36 16 0 13 0 NA NA NA NA NA NA 5318 XR_006394187.1 6 0 7 2 53 NA NA NA NA NA NA 5319 XM_029345899.2 658 510 214 273 142 Q059U7 1.33e-158 Protein inturned (Inturned planar cell polarity effector homolog) (PDZ domain-containing protein 6) Mus musculus (Mouse) cell division [GO:0051301]; cilium assembly [GO:0060271]; embryonic digit morphogenesis [GO:0042733]; establishment of planar polarity [GO:0001736]; hair follicle morphogenesis [GO:0031069]; intraciliary transport [GO:0042073]; keratinocyte differentiation [GO:0030216]; limb development [GO:0060173]; motile cilium assembly [GO:0044458]; negative regulation of cell division [GO:0051782]; negative regulation of keratinocyte proliferation [GO:0010839]; nervous system development [GO:0007399]; neural tube development [GO:0021915]; non-motile cilium assembly [GO:1905515]; positive regulation of smoothened signaling pathway [GO:0045880]; protein localization to organelle [GO:0033365]; regulation of cilium assembly [GO:1902017]; regulation of ossification [GO:0030278]; regulation of smoothened signaling pathway [GO:0008589]; roof of mouth development [GO:0060021]; smoothened signaling pathway [GO:0007224]; spinal cord dorsal/ventral patterning [GO:0021513]; tongue morphogenesis [GO:0043587]; vesicle-mediated transport [GO:0016192] GO:0001736; GO:0005737; GO:0005814; GO:0005929; GO:0007224; GO:0007399; GO:0008589; GO:0009986; GO:0010839; GO:0016192; GO:0021513; GO:0021915; GO:0030216; GO:0030278; GO:0031069; GO:0031514; GO:0033365; GO:0035869; GO:0036064; GO:0042073; GO:0042733; GO:0043587; GO:0044458; GO:0045880; GO:0051301; GO:0051782; GO:0060021; GO:0060173; GO:0060271; GO:1902017; GO:1905515 5320 XM_029337219.2 420 775 190 196 296 Q8BGX0 0 E3 ubiquitin-protein ligase TRIM23 (EC 2.3.2.27) (ADP-ribosylation factor domain-containing protein 1) (GTP-binding protein ARD-1) (RING-type E3 ubiquitin transferase TRIM23) (Tripartite motif-containing protein 23) Mus musculus (Mouse) intracellular protein transport [GO:0006886]; positive regulation of protein modification process [GO:0031401]; protein ubiquitination [GO:0016567]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0003924; GO:0004842; GO:0005525; GO:0005634; GO:0005737; GO:0005765; GO:0005886; GO:0006886; GO:0008270; GO:0016192; GO:0016567; GO:0019003; GO:0031401; GO:0042802 5321 XM_044317763.1 0 66 19 47 87 O43435 1.9e-102 T-box transcription factor TBX1 (T-box protein 1) (Testis-specific T-box protein) Homo sapiens (Human) angiogenesis [GO:0001525]; anterior/posterior pattern specification [GO:0009952]; aorta morphogenesis [GO:0035909]; artery morphogenesis [GO:0048844]; blood vessel development [GO:0001568]; blood vessel morphogenesis [GO:0048514]; cell fate specification [GO:0001708]; cell population proliferation [GO:0008283]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to retinoic acid [GO:0071300]; cochlea morphogenesis [GO:0090103]; coronary artery morphogenesis [GO:0060982]; determination of left/right symmetry [GO:0007368]; ear morphogenesis [GO:0042471]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic viscerocranium morphogenesis [GO:0048703]; enamel mineralization [GO:0070166]; epithelial cell differentiation [GO:0030855]; face morphogenesis [GO:0060325]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; inner ear morphogenesis [GO:0042472]; lymph vessel development [GO:0001945]; mesenchymal cell apoptotic process [GO:0097152]; mesoderm development [GO:0007498]; middle ear morphogenesis [GO:0042474]; muscle cell fate commitment [GO:0042693]; muscle organ development [GO:0007517]; muscle organ morphogenesis [GO:0048644]; muscle tissue morphogenesis [GO:0060415]; negative regulation of cell differentiation [GO:0045596]; negative regulation of mesenchymal cell apoptotic process [GO:2001054]; neural crest cell migration [GO:0001755]; odontogenesis of dentin-containing tooth [GO:0042475]; outer ear morphogenesis [GO:0042473]; outflow tract morphogenesis [GO:0003151]; outflow tract septum morphogenesis [GO:0003148]; parathyroid gland development [GO:0060017]; pattern specification process [GO:0007389]; pharyngeal system development [GO:0060037]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of tongue muscle cell differentiation [GO:2001037]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of animal organ morphogenesis [GO:2000027]; regulation of transcription by RNA polymerase II [GO:0006357]; retinoic acid receptor signaling pathway [GO:0048384]; semicircular canal morphogenesis [GO:0048752]; sensory perception of sound [GO:0007605]; social behavior [GO:0035176]; soft palate development [GO:0060023]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; tongue morphogenesis [GO:0043587]; vagus nerve morphogenesis [GO:0021644] GO:0000785; GO:0000978; GO:0000981; GO:0001525; GO:0001568; GO:0001708; GO:0001755; GO:0001934; GO:0001945; GO:0002053; GO:0003007; GO:0003148; GO:0003151; GO:0003677; GO:0005634; GO:0006357; GO:0007368; GO:0007389; GO:0007498; GO:0007507; GO:0007517; GO:0007605; GO:0008283; GO:0008284; GO:0009952; GO:0021644; GO:0030855; GO:0030878; GO:0035176; GO:0035909; GO:0042471; GO:0042472; GO:0042473; GO:0042474; GO:0042475; GO:0042693; GO:0042803; GO:0043410; GO:0043565; GO:0043587; GO:0044344; GO:0045596; GO:0045893; GO:0045944; GO:0046983; GO:0048384; GO:0048514; GO:0048538; GO:0048644; GO:0048701; GO:0048703; GO:0048752; GO:0048844; GO:0050679; GO:0060017; GO:0060023; GO:0060037; GO:0060325; GO:0060415; GO:0060982; GO:0070166; GO:0071300; GO:0090103; GO:0097152; GO:1990837; GO:2000027; GO:2001037; GO:2001054 5322 XR_006398061.1 37 8 13 32 7 NA NA NA NA NA NA 5323 XM_044326762.1 0 0 0 6 3 Q99315 4.41e-82 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 5324 XM_044325109.1 5 0 11 0 0 NA NA NA NA NA NA 5325 XM_044328621.1 542 1 19 17 3 NA NA NA NA NA NA 5326 XM_029333749.2 1585 990 710 1530 1004 Q9H4B6 1.57e-47 Protein salvador homolog 1 (45 kDa WW domain protein) (hWW45) Homo sapiens (Human) cardiac muscle cell proliferation [GO:0060038]; epithelial cell proliferation [GO:0050673]; hair follicle development [GO:0001942]; hippo signaling [GO:0035329]; intestinal epithelial cell differentiation [GO:0060575]; keratinocyte apoptotic process [GO:0097283]; keratinocyte differentiation [GO:0030216]; lung epithelial cell differentiation [GO:0060487]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of epithelial cell proliferation [GO:0050680]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of keratinocyte apoptotic process [GO:1902174]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of stem cell population maintenance [GO:2000036]; signal transduction [GO:0007165]; ventricular septum morphogenesis [GO:0060412] GO:0001942; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0005911; GO:0007165; GO:0030159; GO:0030216; GO:0030425; GO:0031697; GO:0035329; GO:0042802; GO:0043113; GO:0045600; GO:0046332; GO:0050673; GO:0050680; GO:0050821; GO:0051091; GO:0060038; GO:0060044; GO:0060412; GO:0060487; GO:0060575; GO:0070699; GO:0097283; GO:1902174; GO:2000036 5327 XM_029329891.2 479 229 256 495 707 Q3BCR4 6.12e-34 Thiopurine S-methyltransferase (EC 2.1.1.67) (Thiopurine methyltransferase) Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops) methylation [GO:0032259] GO:0005737; GO:0008119; GO:0032259 5328 XM_044316129.1 0 3 6 0 45 D3YXG0 6.98e-32 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 5329 XM_044316129.1 0 3 6 0 45 D3YXG0 2.25e-30 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 5330 XM_044316129.1 0 3 6 0 45 D3YXG0 1.59e-29 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 5331 XM_044316129.1 0 3 6 0 45 D3YXG0 6.48e-29 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 5332 XM_044316129.1 0 3 6 0 45 D3YXG0 1.98e-27 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 5333 XM_044316129.1 0 3 6 0 45 D3YXG0 8.9e-27 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 5334 XM_044316129.1 0 3 6 0 45 D3YXG0 3.88e-26 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 5335 XM_044316129.1 0 3 6 0 45 D3YXG0 6.36e-26 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 5336 XM_044316129.1 0 3 6 0 45 D3YXG0 4.24e-25 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 5337 XM_044316129.1 0 3 6 0 45 D3YXG0 5.08e-25 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 5338 XM_044316129.1 0 3 6 0 45 D3YXG0 7.87e-25 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 5339 XM_044316129.1 0 3 6 0 45 D3YXG0 1.97e-24 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 5340 XM_044316129.1 0 3 6 0 45 D3YXG0 3.82e-24 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 5341 XM_044316129.1 0 3 6 0 45 D3YXG0 1.15e-23 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 5342 XM_044316129.1 0 3 6 0 45 D3YXG0 1.93e-22 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 5343 XM_044316129.1 0 3 6 0 45 D3YXG0 3.23e-22 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 5344 XM_044316129.1 0 3 6 0 45 D3YXG0 6.67e-21 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 5345 XR_006397686.1 0 15 9 18 26 NA NA NA NA NA NA 5346 XM_029327576.2 19 0 4 0 43 NA NA NA NA NA NA 5347 XM_044319203.1 375 308 279 463 387 NA NA NA NA NA NA 5348 XR_006398045.1 14 0 2 6 19 NA NA NA NA NA NA 5349 XR_006396280.1 401 173 221 275 314 P16157 1.35e-58 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 5350 XR_006396280.1 401 173 221 275 314 P16157 1.35e-58 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 5351 XR_006396280.1 401 173 221 275 314 P16157 7.04e-41 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 5352 XR_006396280.1 401 173 221 275 314 P16157 7.04e-41 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 5353 XR_006396280.1 401 173 221 275 314 P16157 8.14e-38 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 5354 XR_006396280.1 401 173 221 275 314 P16157 1.75e-35 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 5355 XR_006396280.1 401 173 221 275 314 P16157 5.77e-31 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 5356 XR_006396280.1 401 173 221 275 314 P16157 5.77e-31 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 5357 XR_006396280.1 401 173 221 275 314 P16157 1.71e-23 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 5358 XR_006396280.1 401 173 221 275 314 P16157 1.71e-23 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 5359 XM_044323524.1 472 99 182 109 165 NA NA NA NA NA NA 5360 XM_044324939.1 287 156 268 425 339 P35409 5.9e-137 Probable glycoprotein hormone G-protein coupled receptor Anthopleura elegantissima (Green aggregating anemone) (Actinia elegantissima) NA GO:0004930; GO:0005886; GO:0016500 5361 XM_044324939.1 287 156 268 425 339 P35409 3.14e-28 Probable glycoprotein hormone G-protein coupled receptor Anthopleura elegantissima (Green aggregating anemone) (Actinia elegantissima) NA GO:0004930; GO:0005886; GO:0016500 5362 XM_044324939.1 287 156 268 425 339 P35409 3.14e-28 Probable glycoprotein hormone G-protein coupled receptor Anthopleura elegantissima (Green aggregating anemone) (Actinia elegantissima) NA GO:0004930; GO:0005886; GO:0016500 5363 XR_003826718.2 508 193 198 316 517 NA NA NA NA NA NA 5364 XM_044311796.1 17 1 9 61 14 NA NA NA NA NA NA 5365 XM_044322862.1 1281 893 951 1859 1434 P23588 4.97e-28 Eukaryotic translation initiation factor 4B (eIF-4B) Homo sapiens (Human) eukaryotic translation initiation factor 4F complex assembly [GO:0097010]; formation of translation preinitiation complex [GO:0001731]; regulation of translational initiation [GO:0006446] GO:0001731; GO:0003723; GO:0003743; GO:0005829; GO:0006446; GO:0016281; GO:0033592; GO:0034057; GO:0043024; GO:0097010 5366 XM_044323369.1 1111 561 524 904 532 Q5ZMC3 1.27e-55 WD repeat, SAM and U-box domain-containing protein 1 Gallus gallus (Chicken) NA GO:0004842 5367 XM_044315983.1 17 49 0 125 17 R1CW23 1.36e-101 Dimethylsulfonioproprionate lyase 7 (DMSP lyase 7) (EC 4.4.1.3) (Dimethylpropiothetin dethiomethylase 7) Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi) NA GO:0047869 5368 XM_029356170.2 6 0 0 0 0 Q96A58 1.03e-35 Ras-related and estrogen-regulated growth inhibitor (EC 3.6.5.2) Homo sapiens (Human) negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; Ras protein signal transduction [GO:0007265]; response to hormone [GO:0009725]; small GTPase mediated signal transduction [GO:0007264] GO:0001650; GO:0003924; GO:0003925; GO:0005525; GO:0005634; GO:0005654; GO:0005829; GO:0005886; GO:0007264; GO:0007265; GO:0008285; GO:0009725; GO:0019003; GO:0030308; GO:0030331 5369 XM_029337666.2 0 0 0 24 0 Q5YCC5 2.45e-69 Transmembrane channel-like protein 7 Gallus gallus (Chicken) NA GO:0005886; GO:0008381 5370 XM_029343934.2 0 47 46 92 0 NA NA NA NA NA NA 5371 XM_029325998.2 1 0 13 31 15 NA NA NA NA NA NA 5372 XM_044307915.1 6 10 0 0 5 NA NA NA NA NA NA 5373 XM_029324060.2 269 736 466 993 652 Q6QLW4 5.23e-63 Cytochrome c Pectinaria gouldii (Trumpet worm) (Ice-cream cone worm) NA GO:0005758; GO:0009055; GO:0020037; GO:0046872; GO:0070469 5374 XM_029324286.2 28 6 14 3 8 NA NA NA NA NA NA 5375 XM_044325840.1 33 16 26 79 63 Q6GQT9 1.68e-27 BOS complex subunit NOMO1 (Nodal modulator 1) Mus musculus (Mouse) NA GO:0005789; GO:0030246; GO:0032991; GO:0043022 5376 XM_044319473.1 1 29 0 0 110 NA NA NA NA NA NA 5377 XM_029331204.2 209 169 140 144 241 Q9CZ57 2.09e-56 5-methylcytosine rRNA methyltransferase NSUN4 (EC 2.1.1.-) (5-methylcytosine tRNA methyltransferase NSUN4) (EC 2.1.1.-) (NOL1/NOP2/Sun domain family member 4) (Sperm head and tail associated protein) Mus musculus (Mouse) cytosolic ribosome assembly [GO:0042256]; positive regulation of mitochondrial translation [GO:0070131]; RNA methylation [GO:0001510]; rRNA methylation [GO:0031167]; tRNA methylation [GO:0030488] GO:0000049; GO:0001510; GO:0005634; GO:0005737; GO:0005739; GO:0005762; GO:0008168; GO:0009383; GO:0016428; GO:0030488; GO:0031167; GO:0042256; GO:0070131; GO:0070181 5378 XM_029331595.2 171 83 48 105 159 Q803U7 5.13e-97 Exonuclease 1 (EC 3.1.-.-) (Exonuclease I) Danio rerio (Zebrafish) (Brachydanio rerio) DNA recombination [GO:0006310]; mismatch repair [GO:0006298] GO:0003677; GO:0005634; GO:0006298; GO:0006310; GO:0017108; GO:0035312; GO:0045145; GO:0046872; GO:0048256 5379 XM_029336893.2 22 1 19 0 0 NA NA NA NA NA NA 5380 XM_029347121.2 9 9 0 2 1 NA NA NA NA NA NA 5381 XR_006395531.1 0 186 11 132 80 P53992 0 Protein transport protein Sec24C (SEC24-related protein C) Homo sapiens (Human) COPII-coated vesicle cargo loading [GO:0090110]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; in utero embryonic development [GO:0001701]; intracellular protein transport [GO:0006886] GO:0000149; GO:0001701; GO:0005789; GO:0005829; GO:0006886; GO:0006888; GO:0008270; GO:0012507; GO:0030127; GO:0070971; GO:0090110 5382 XM_029326539.2 0 0 0 50 46 Q69Z28 7.55e-158 A disintegrin and metalloproteinase with thrombospondin motifs 16 (ADAM-TS 16) (ADAM-TS16) (ADAMTS-16) (EC 3.4.24.-) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; extracellular matrix organization [GO:0030198]; male gamete generation [GO:0048232]; proteolysis [GO:0006508]; regulation of cilium assembly [GO:1902017]; regulation of systemic arterial blood pressure [GO:0003073] GO:0001658; GO:0003073; GO:0004222; GO:0005576; GO:0006508; GO:0030198; GO:0031012; GO:0046872; GO:0048232; GO:1902017 5383 XM_044327577.1 11 3 0 0 18 NA NA NA NA NA NA 5384 XR_006397578.1 4 0 7 12 18 NA NA NA NA NA NA 5385 XR_003827262.2 431 601 235 1316 605 NA NA NA NA NA NA 5386 XM_029357883.2 2631 2082 1355 2468 2213 P05202 0 Aspartate aminotransferase, mitochondrial (mAspAT) (EC 2.6.1.1) (EC 2.6.1.7) (Fatty acid-binding protein) (FABP-1) (Glutamate oxaloacetate transaminase 2) (Kynurenine aminotransferase 4) (Kynurenine aminotransferase IV) (Kynurenine--oxoglutarate transaminase 4) (Kynurenine--oxoglutarate transaminase IV) (Plasma membrane-associated fatty acid-binding protein) (FABPpm) (Transaminase A) Mus musculus (Mouse) 2-oxoglutarate metabolic process [GO:0006103]; amino acid metabolic process [GO:0006520]; aspartate biosynthetic process [GO:0006532]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; dicarboxylic acid metabolic process [GO:0043648]; fatty acid transport [GO:0015908]; glutamate catabolic process to 2-oxoglutarate [GO:0019551]; glutamate catabolic process to aspartate [GO:0019550]; glutamate metabolic process [GO:0006536]; oxaloacetate metabolic process [GO:0006107]; response to ethanol [GO:0045471] GO:0004069; GO:0005543; GO:0005739; GO:0005743; GO:0005759; GO:0005886; GO:0006103; GO:0006107; GO:0006520; GO:0006531; GO:0006532; GO:0006533; GO:0006536; GO:0009986; GO:0015908; GO:0016212; GO:0016597; GO:0019550; GO:0019551; GO:0019899; GO:0030170; GO:0030315; GO:0031406; GO:0032991; GO:0042383; GO:0042802; GO:0043204; GO:0043209; GO:0043648; GO:0045471 5387 XM_029324828.2 733 652 339 865 398 Q96PV6 3.63e-101 Leukocyte receptor cluster member 8 Homo sapiens (Human) NA GO:0005634; GO:0032991 5388 XM_029342618.2 135 96 40 82 164 Q6NSI4 1.58e-68 RPA-related protein RADX (RPA-related and RAD51-antagonist, X-chromosome) Homo sapiens (Human) negative regulation of double-strand break repair via homologous recombination [GO:2000042]; regulation of DNA repair [GO:0006282] GO:0003697; GO:0003723; GO:0005657; GO:0006282; GO:0016607; GO:2000042 5389 XM_044320857.1 24 0 123 29 85 O43422 6.74e-29 52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (Death-associated protein 4) (THAP domain-containing protein 0) (THAP domain-containing protein 12) Homo sapiens (Human) negative regulation of cell population proliferation [GO:0008285]; signal transduction [GO:0007165] GO:0003677; GO:0005634; GO:0007165; GO:0008285; GO:0046872; GO:0046983 5390 XM_044320857.1 24 0 123 29 85 O43422 6.74e-29 52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (Death-associated protein 4) (THAP domain-containing protein 0) (THAP domain-containing protein 12) Homo sapiens (Human) negative regulation of cell population proliferation [GO:0008285]; signal transduction [GO:0007165] GO:0003677; GO:0005634; GO:0007165; GO:0008285; GO:0046872; GO:0046983 5391 XM_044306814.1 287 239 225 317 426 Q5U3S7 2.82e-108 Nitric oxide synthase-interacting protein (E3 ubiquitin-protein ligase NOSIP) (EC 2.3.2.27) (RING-type E3 ubiquitin transferase NOSIP) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005634; GO:0005737; GO:0061630 5392 XM_044310728.1 7 0 1 7 40 NA NA NA NA NA NA 5393 XM_029340107.2 36 160 71 134 85 NA NA NA NA NA NA 5394 XM_029339167.2 399 334 230 188 273 O73747 5.2e-65 Protein FRG1 Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) muscle organ development [GO:0007517]; rRNA processing [GO:0006364] GO:0003723; GO:0003779; GO:0005730; GO:0006364; GO:0007517; GO:0015030; GO:0030018 5395 XM_029333574.2 319 1060 688 1163 662 Q98948 3.62e-53 Single-stranded DNA-binding protein 3 (Sequence-specific single-stranded-DNA-binding protein) Gallus gallus (Chicken) positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0003697; GO:0005634; GO:0045944 5396 XM_044310526.1 8 32 31 13 14 Q58L91 3.89e-25 Venom prothrombin activator oscutarin-C non-catalytic subunit (vPA) (Venom coagulation factor Va-like protein) [Cleaved into: Oscutarin-C non-catalytic subunit heavy chain; Oscutarin-C non-catalytic subunit light chain] Oxyuranus scutellatus (Coastal taipan) envenomation resulting in positive regulation of blood coagulation in another organism [GO:0044469]; positive regulation of blood coagulation in another organism [GO:0035807]; positive regulation of peptidase activity [GO:0010952] GO:0005507; GO:0005576; GO:0010952; GO:0016504; GO:0032991; GO:0035807; GO:0044469; GO:0090729 5397 XM_029329193.2 18 7 7 11 30 NA NA NA NA NA NA 5398 XM_044310056.1 1016 1838 727 918 919 NA NA NA NA NA NA 5399 XM_029338078.2 621 377 289 552 385 P07314 5.86e-112 Glutathione hydrolase 1 proenzyme (EC 3.4.19.13) (Gamma-glutamyltransferase 1) (Gamma-glutamyltranspeptidase 1) (GGT 1) (EC 2.3.2.2) (Leukotriene-C4 hydrolase) (EC 3.4.19.14) (CD antigen CD224) [Cleaved into: Glutathione hydrolase 1 heavy chain; Glutathione hydrolase 1 light chain] Rattus norvegicus (Rat) aging [GO:0007568]; amino acid metabolic process [GO:0006520]; cellular response to oxidative stress [GO:0034599]; cysteine biosynthetic process [GO:0019344]; fatty acid metabolic process [GO:0006631]; glutamate metabolic process [GO:0006536]; glutathione biosynthetic process [GO:0006750]; glutathione catabolic process [GO:0006751]; hepatoblast differentiation [GO:0061017]; hepatocyte differentiation [GO:0070365]; leukotriene D4 biosynthetic process [GO:1901750]; leukotriene metabolic process [GO:0006691]; liver regeneration [GO:0097421]; peptide modification [GO:0031179]; proteolysis [GO:0006508]; regulation of immune system process [GO:0002682]; regulation of inflammatory response [GO:0050727]; response to alcohol [GO:0097305]; response to estradiol [GO:0032355]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]; spermatogenesis [GO:0007283]; zymogen activation [GO:0031638] GO:0000048; GO:0002682; GO:0002951; GO:0005615; GO:0005886; GO:0006508; GO:0006520; GO:0006536; GO:0006631; GO:0006691; GO:0006750; GO:0006751; GO:0007283; GO:0007568; GO:0016755; GO:0019344; GO:0031179; GO:0031638; GO:0031982; GO:0032355; GO:0032496; GO:0034599; GO:0034612; GO:0036374; GO:0050727; GO:0061017; GO:0070365; GO:0097305; GO:0097421; GO:0102953; GO:0103068; GO:1901750 5400 XM_044325610.1 544 481 225 357 172 Q803I2 0 Endoplasmic reticulum-Golgi intermediate compartment protein 3 Danio rerio (Zebrafish) (Brachydanio rerio) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] GO:0000139; GO:0005783; GO:0005789; GO:0006888; GO:0006890; GO:0016020; GO:0030134; GO:0033116 5401 XR_006395958.1 0 21 15 1 9 NA NA NA NA NA NA 5402 XR_006392990.1 41 2 25 5 151 NA NA NA NA NA NA 5403 XM_029333581.2 10 0 0 11 1 NA NA NA NA NA NA 5404 XM_044325795.1 2 0 0 1 11 NA NA NA NA NA NA 5405 XM_044314216.1 845 138 348 410 509 NA NA NA NA NA NA 5406 XM_044308948.1 135 61 39 91 47 C6FG12 1.61e-24 Protein NLRC5 Ictalurus punctatus (Channel catfish) (Silurus punctatus) innate immune response [GO:0045087] GO:0005524; GO:0005737; GO:0045087 5407 XR_006396157.1 8 62 0 9 46 NA NA NA NA NA NA 5408 XR_003828647.2 103 0 27 5 12 NA NA NA NA NA NA 5409 XM_044325228.1 36 15 8 32 55 P97738 1.58e-26 Neuronal pentraxin-2 (NP2) (Neuronal activity-regulated pentraxin) (Neuronal pentraxin II) (NP-II) Rattus norvegicus (Rat) associative learning [GO:0008306]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962] GO:0008306; GO:0030246; GO:0043083; GO:0046872; GO:0098892; GO:0098962; GO:0098978; GO:0099645 5410 XM_029335594.2 2707 1659 957 2094 735 NA NA NA NA NA NA 5411 XM_029349818.2 8530 7464 6057 7744 6560 A6QL50 5.17e-48 Protein FAM72A Bos taurus (Bovine) NA GO:0005739; GO:0005829 5412 XM_044318554.1 19 4 3 0 0 Q68F72 4.07e-81 Solute carrier family 15 member 4 Xenopus laevis (African clawed frog) dipeptide import across plasma membrane [GO:0140206]; innate immune response [GO:0045087]; mast cell homeostasis [GO:0033023]; peptidoglycan transport [GO:0015835]; positive regulation of innate immune response [GO:0045089]; positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [GO:0070430]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of toll-like receptor 7 signaling pathway [GO:0034157]; positive regulation of toll-like receptor 8 signaling pathway [GO:0034161]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; protein transport [GO:0015031]; regulation of isotype switching to IgG isotypes [GO:0048302]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424] GO:0005290; GO:0005765; GO:0015031; GO:0015333; GO:0015647; GO:0015835; GO:0031901; GO:0033023; GO:0034157; GO:0034161; GO:0034165; GO:0036020; GO:0045087; GO:0045089; GO:0048302; GO:0070424; GO:0070430; GO:0070434; GO:0071916; GO:0140206 5413 XM_029328704.2 0 1 6 9 172 C6KI89 1.41e-38 Cation channel sperm-associated auxiliary subunit gamma 2 Mus musculus (Mouse) cell differentiation [GO:0030154]; spermatogenesis [GO:0007283] GO:0007283; GO:0030154; GO:0031514; GO:0036128; GO:0097228 5414 XM_044307526.1 30 27 81 18 63 Q8C0T9 1.17e-21 Adenylate cyclase type 10 (EC 4.6.1.1) (Germ cell soluble adenylyl cyclase) (sAC) (Testicular soluble adenylyl cyclase) Mus musculus (Mouse) cAMP biosynthetic process [GO:0006171]; cellular response to inorganic substance [GO:0071241]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; intracellular signal transduction [GO:0035556]; positive regulation of apoptotic process [GO:0043065]; spermatogenesis [GO:0007283] GO:0000287; GO:0003351; GO:0004016; GO:0005524; GO:0005576; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0006171; GO:0007283; GO:0015630; GO:0016020; GO:0016324; GO:0030145; GO:0030424; GO:0030425; GO:0030426; GO:0031514; GO:0035556; GO:0043025; GO:0043065; GO:0045177; GO:0045178; GO:0048471; GO:0051117; GO:0071241; GO:0071890 5415 XM_029358372.2 17 0 7 2 28 Q5RKJ1 7.11e-145 E3 ubiquitin-protein transferase MAEA (EC 2.3.2.27) (Macrophage erythroblast attacher) Rattus norvegicus (Rat) cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell division [GO:0051301]; cytoskeleton organization [GO:0007010]; enucleate erythrocyte development [GO:0048822]; erythrocyte development [GO:0048821]; erythrocyte maturation [GO:0043249]; negative regulation of myeloid cell apoptotic process [GO:0033033]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] GO:0000151; GO:0003779; GO:0005634; GO:0005654; GO:0005737; GO:0005819; GO:0005826; GO:0005856; GO:0005886; GO:0007010; GO:0007049; GO:0007155; GO:0015629; GO:0016363; GO:0033033; GO:0034657; GO:0043161; GO:0043249; GO:0046872; GO:0048821; GO:0048822; GO:0051301; GO:0061630 5416 XM_029326633.2 60 64 32 7 30 B0UYI1 6.48e-47 Transcription elongation factor A N-terminal and central domain-containing protein 2 Danio rerio (Zebrafish) (Brachydanio rerio) DNA-templated transcription [GO:0006351] GO:0005634; GO:0006351 5417 XM_044324836.1 3023 1495 1483 4887 5187 P20909 1.7e-45 Collagen alpha-1(XI) chain Rattus norvegicus (Rat) cartilage condensation [GO:0001502]; cartilage development [GO:0051216]; chondrocyte development [GO:0002063]; collagen fibril organization [GO:0030199]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; embryonic skeletal system morphogenesis [GO:0048704]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; heart morphogenesis [GO:0003007]; inner ear morphogenesis [GO:0042472]; ossification [GO:0001503]; proteoglycan metabolic process [GO:0006029]; sensory perception of sound [GO:0007605]; skeletal system morphogenesis [GO:0048705]; tendon development [GO:0035989]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; visual perception [GO:0007601] GO:0001502; GO:0001503; GO:0002063; GO:0003007; GO:0005201; GO:0005581; GO:0005592; GO:0005615; GO:0006029; GO:0007601; GO:0007605; GO:0008201; GO:0030198; GO:0030199; GO:0031012; GO:0035987; GO:0035989; GO:0042472; GO:0046872; GO:0048704; GO:0048705; GO:0050910; GO:0051216; GO:0055010; GO:0062023; GO:1904399 5418 XM_029339215.2 224 47 445 80 220 Q5RDQ2 2.72e-162 Protein PALS1 (MAGUK p55 subfamily member 5) (Protein associated with Lin-7 1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) central nervous system neuron development [GO:0021954]; cerebral cortex development [GO:0021987]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015] GO:0005524; GO:0005794; GO:0005912; GO:0005923; GO:0016324; GO:0017015; GO:0021954; GO:0021987; GO:0030424; GO:0043204 5419 XR_006395911.1 615 129 157 172 7 NA NA NA NA NA NA 5420 XM_044308802.1 254 104 91 81 202 NA NA NA NA NA NA 5421 XM_044316497.1 5 9 0 0 15 Q91770 1.32e-24 Homeobox protein not2 (Xnot-2) (Xnot2) Xenopus laevis (African clawed frog) negative regulation of DNA-templated transcription [GO:0045892]; notochord formation [GO:0014028] GO:0000981; GO:0003677; GO:0005634; GO:0014028; GO:0045892 5422 XM_044308155.1 966 406 637 1195 1124 Q502I9 7.11e-81 F-BAR domain only protein 2 Danio rerio (Zebrafish) (Brachydanio rerio) chordate embryonic development [GO:0043009]; clathrin coat assembly [GO:0048268]; clathrin-dependent endocytosis [GO:0072583]; membrane invagination [GO:0010324]; protein localization to plasma membrane [GO:0072659]; synaptic vesicle endocytosis [GO:0048488] GO:0001786; GO:0005546; GO:0005737; GO:0005886; GO:0005905; GO:0010324; GO:0030136; GO:0035091; GO:0043009; GO:0048268; GO:0048488; GO:0072583; GO:0072659; GO:0098793 5423 XM_044308155.1 966 406 637 1195 1124 Q502I9 1.84e-55 F-BAR domain only protein 2 Danio rerio (Zebrafish) (Brachydanio rerio) chordate embryonic development [GO:0043009]; clathrin coat assembly [GO:0048268]; clathrin-dependent endocytosis [GO:0072583]; membrane invagination [GO:0010324]; protein localization to plasma membrane [GO:0072659]; synaptic vesicle endocytosis [GO:0048488] GO:0001786; GO:0005546; GO:0005737; GO:0005886; GO:0005905; GO:0010324; GO:0030136; GO:0035091; GO:0043009; GO:0048268; GO:0048488; GO:0072583; GO:0072659; GO:0098793 5424 XM_029342586.2 1266 1196 740 927 1278 Q8BH70 1.56e-125 F-box/LRR-repeat protein 4 (F-box and leucine-rich repeat protein 4) Mus musculus (Mouse) autophagy of mitochondrion [GO:0000422]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0000422; GO:0005758; GO:0016607; GO:0019005; GO:0031146 5425 XM_044310466.1 57 103 198 0 213 NA NA NA NA NA NA 5426 XM_029336084.2 7 89 81 74 30 P20823 9.77e-79 Hepatocyte nuclear factor 1-alpha (HNF-1-alpha) (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1) (Transcription factor 1) (TCF-1) Homo sapiens (Human) glucose homeostasis [GO:0042593]; glucose import [GO:0046323]; insulin secretion [GO:0030073]; liver development [GO:0001889]; pancreas development [GO:0031016]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; regulation of transcription by RNA polymerase II [GO:0006357]; renal glucose absorption [GO:0035623] GO:0000785; GO:0000976; GO:0000978; GO:0000981; GO:0001228; GO:0001889; GO:0003677; GO:0003700; GO:0005634; GO:0005737; GO:0006357; GO:0030073; GO:0031016; GO:0032991; GO:0035623; GO:0042593; GO:0042803; GO:0045893; GO:0045944; GO:0046323; GO:0046982; GO:0046983; GO:0060261 5427 XM_029337322.2 3366 1897 1968 1869 3813 NA NA NA NA NA NA 5428 XM_029325165.2 1995 1071 1003 1569 1540 O00267 0 Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor 160 kDa subunit) (DSIF p160) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (Tat-cotransactivator 1 protein) (Tat-CT1 protein) Homo sapiens (Human) negative regulation of DNA-templated transcription, elongation [GO:0032785]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of macroautophagy [GO:0016239]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription elongation by RNA polymerase II [GO:0034243]; transcription elongation by RNA polymerase II promoter [GO:0006368]; transcription elongation-coupled chromatin remodeling [GO:0140673] GO:0000122; GO:0003682; GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0006357; GO:0006368; GO:0016239; GO:0019899; GO:0032044; GO:0032785; GO:0032786; GO:0034243; GO:0045944; GO:0046982; GO:0140673 5429 XM_029348941.2 15 31 0 0 0 O54852 6.93e-102 Potassium voltage-gated channel subfamily H member 7 (Ether-a-go-go-related gene potassium channel 3) (ERG-3) (Eag-related protein 3) (Ether-a-go-go-related protein 3) (Voltage-gated potassium channel subunit Kv11.3) Rattus norvegicus (Rat) circadian rhythm [GO:0007623]; membrane repolarization during action potential [GO:0086011]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391] GO:0005242; GO:0005249; GO:0005267; GO:0005886; GO:0006813; GO:0007623; GO:0034765; GO:0042391; GO:0044877; GO:0071805; GO:0086011 5430 XM_044318879.1 0 293 61 479 0 Q56UN5 2.91e-100 Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in COPD, protein kinase) (SPS1/STE20-related protein kinase YSK4) Homo sapiens (Human) protein phosphorylation [GO:0006468]; signal transduction [GO:0007165] GO:0004672; GO:0004674; GO:0005524; GO:0006468; GO:0007165; GO:0106310 5431 XR_006393620.1 53 1 182 16 301 NA NA NA NA NA NA 5432 XM_044307393.1 98 105 73 66 237 NA NA NA NA NA NA 5433 XM_029349447.2 235 193 177 303 353 Q9ULJ7 3.12e-56 Ankyrin repeat domain-containing protein 50 Homo sapiens (Human) endocytic recycling [GO:0032456]; protein transport [GO:0015031] GO:0005768; GO:0015031; GO:0032456 5434 XR_003828644.2 161 309 352 123 405 NA NA NA NA NA NA 5435 XM_044324014.1 0 0 0 7 0 NA NA NA NA NA NA 5436 XM_029350579.2 7746 5701 4318 5514 6759 Q6DIF4 0 WD repeat-containing protein 1 (Actin-interacting protein 1) (AIP1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) actin filament fragmentation [GO:0030043] GO:0003779; GO:0005634; GO:0005737; GO:0005884; GO:0005886; GO:0030043; GO:0051015 5437 XR_006391402.1 17 2 2 28 25 NA NA NA NA NA NA 5438 XM_029339716.2 390 329 326 459 601 A7SNR3 1.84e-82 Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial (Coenzyme Q biosynthesis protein 4 homolog) Nematostella vectensis (Starlet sea anemone) ubiquinone biosynthetic process [GO:0006744] GO:0005739; GO:0006744; GO:0031314 5439 XM_029342466.2 76 61 42 217 287 NA NA NA NA NA NA 5440 XM_044323189.1 0 0 0 0 13 Q09575 2.13e-33 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 5441 XM_029354351.2 371 99 90 166 133 Q8TF61 7.98e-60 F-box only protein 41 Homo sapiens (Human) NA GO:0005829 5442 XM_044310186.1 0 0 0 6 0 NA NA NA NA NA NA 5443 XR_006395277.1 0 0 1 0 12 NA NA NA NA NA NA 5444 XM_044314789.1 0 0 1 0 35 NA NA NA NA NA NA 5445 XM_029341699.2 10 20 12 33 8 A0A0C2SRU0 3.98e-77 Decarboxylase iboD (EC 4.1.1.-) (Ibotenic acid biosynthesis cluster protein D) Amanita muscaria (strain Koide BX008) phospholipid biosynthetic process [GO:0008654] GO:0004609; GO:0008654 5446 XR_006393909.1 41 2 25 5 151 NA NA NA NA NA NA 5447 XM_029335059.2 582 407 192 370 360 P97698 6.4e-158 Smoothened homolog (SMO) Rattus norvegicus (Rat) alpha-tubulin acetylation [GO:0071929]; anterior/posterior pattern specification [GO:0009952]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; atrial septum morphogenesis [GO:0060413]; axon extension involved in axon guidance [GO:0048846]; cell development [GO:0048468]; cell fate specification [GO:0001708]; cell population proliferation [GO:0008283]; cellular response to cholesterol [GO:0071397]; central nervous system development [GO:0007417]; central nervous system neuron differentiation [GO:0021953]; cerebellar cortex morphogenesis [GO:0021696]; cerebral cortex development [GO:0021987]; commissural neuron axon guidance [GO:0071679]; contact inhibition [GO:0060242]; dentate gyrus development [GO:0021542]; determination of left/right asymmetry in lateral mesoderm [GO:0003140]; determination of left/right symmetry [GO:0007368]; developmental growth [GO:0048589]; digestive tract development [GO:0048565]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral neural tube patterning [GO:0021904]; dorsal/ventral pattern formation [GO:0009953]; embryonic organ development [GO:0048568]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation [GO:0050673]; epithelial-mesenchymal cell signaling [GO:0060684]; facial nerve development [GO:0021561]; forebrain morphogenesis [GO:0048853]; hair follicle development [GO:0001942]; hair follicle morphogenesis [GO:0031069]; heart looping [GO:0001947]; heart morphogenesis [GO:0003007]; homeostasis of number of cells within a tissue [GO:0048873]; in utero embryonic development [GO:0001701]; left/right axis specification [GO:0070986]; mammary gland epithelial cell differentiation [GO:0060644]; mesenchymal to epithelial transition [GO:0060231]; mesenchymal to epithelial transition involved in metanephric renal vesicle formation [GO:0072285]; midgut development [GO:0007494]; multicellular organism growth [GO:0035264]; myoblast migration [GO:0051451]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of epithelial cell differentiation [GO:0030857]; negative regulation of gene expression [GO:0010629]; negative regulation of hair follicle development [GO:0051799]; negative regulation of hepatocyte proliferation [GO:2000346]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural crest cell migration [GO:0001755]; neuroblast proliferation [GO:0007405]; neuron projection regeneration [GO:0031102]; odontogenesis of dentin-containing tooth [GO:0042475]; ossification [GO:0001503]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; pancreas morphogenesis [GO:0061113]; pattern specification process [GO:0007389]; positive regulation of autophagy [GO:0010508]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of gene expression [GO:0010628]; positive regulation of hepatic stellate cell activation [GO:2000491]; positive regulation of hh target transcription factor activity [GO:0007228]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of organ growth [GO:0046622]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; protein import into nucleus [GO:0006606]; protein localization to nucleus [GO:0034504]; protein stabilization [GO:0050821]; regulation of gene expression [GO:0010468]; regulation of heart morphogenesis [GO:2000826]; regulation of somatic stem cell population maintenance [GO:1904672]; regulation of stem cell population maintenance [GO:2000036]; response to organic substance [GO:0010033]; response to wounding [GO:0009611]; skeletal muscle fiber development [GO:0048741]; smooth muscle tissue development [GO:0048745]; smoothened signaling pathway [GO:0007224]; smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation [GO:0021938]; smoothened signaling pathway involved in ventral spinal cord patterning [GO:0021910]; somite development [GO:0061053]; spermatogenesis [GO:0007283]; thalamus development [GO:0021794]; type B pancreatic cell development [GO:0003323]; vasculogenesis [GO:0001570]; ventral midline determination [GO:0007371] GO:0000122; GO:0001503; GO:0001570; GO:0001649; GO:0001701; GO:0001708; GO:0001755; GO:0001942; GO:0001947; GO:0002052; GO:0002053; GO:0003007; GO:0003140; GO:0003323; GO:0004930; GO:0005113; GO:0005634; GO:0005737; GO:0005814; GO:0005886; GO:0005929; GO:0006606; GO:0006915; GO:0007224; GO:0007228; GO:0007283; GO:0007368; GO:0007371; GO:0007389; GO:0007405; GO:0007417; GO:0007494; GO:0008283; GO:0008284; GO:0009611; GO:0009952; GO:0009953; GO:0010033; GO:0010468; GO:0010508; GO:0010628; GO:0010629; GO:0014069; GO:0016020; GO:0021542; GO:0021561; GO:0021696; GO:0021794; GO:0021904; GO:0021910; GO:0021938; GO:0021953; GO:0021987; GO:0030335; GO:0030425; GO:0030855; GO:0030857; GO:0031069; GO:0031102; GO:0033687; GO:0034504; GO:0035264; GO:0040018; GO:0042307; GO:0042475; GO:0043025; GO:0043066; GO:0043231; GO:0043392; GO:0043524; GO:0044294; GO:0044295; GO:0045880; GO:0045892; GO:0045893; GO:0045944; GO:0046622; GO:0048143; GO:0048468; GO:0048565; GO:0048568; GO:0048589; GO:0048741; GO:0048745; GO:0048846; GO:0048853; GO:0048873; GO:0050673; GO:0050679; GO:0050821; GO:0051451; GO:0051799; GO:0060170; GO:0060231; GO:0060242; GO:0060413; GO:0060644; GO:0060684; GO:0061053; GO:0061113; GO:0070986; GO:0071397; GO:0071542; GO:0071679; GO:0071929; GO:0072285; GO:0090190; GO:0097731; GO:1901215; GO:1904672; GO:1904754; GO:2000036; GO:2000179; GO:2000346; GO:2000491; GO:2000826 5448 XM_044312599.1 998 748 297 955 420 NA NA NA NA NA NA 5449 XM_044324103.1 31 5 19 10 71 NA NA NA NA NA NA 5450 XM_044325445.1 80 71 29 163 76 NA NA NA NA NA NA 5451 XM_029330176.2 713 683 149 361 326 A4UTP7 3.39e-63 Myocyte-specific enhancer factor 2C Sus scrofa (Pig) B cell homeostasis [GO:0001782]; B cell proliferation [GO:0042100]; B cell receptor signaling pathway [GO:0050853]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cardiac ventricle formation [GO:0003211]; cardiocyte differentiation [GO:0035051]; cellular response to calcium ion [GO:0071277]; cellular response to fluid shear stress [GO:0071498]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cellular response to trichostatin A [GO:0035984]; cellular response to xenobiotic stimulus [GO:0071466]; chondrocyte differentiation [GO:0002062]; endochondral ossification [GO:0001958]; epithelial cell proliferation involved in renal tubule morphogenesis [GO:2001013]; germinal center formation [GO:0002467]; glomerulus morphogenesis [GO:0072102]; heart development [GO:0007507]; heart looping [GO:0001947]; humoral immune response [GO:0006959]; learning or memory [GO:0007611]; MAPK cascade [GO:0000165]; melanocyte differentiation [GO:0030318]; muscle cell fate determination [GO:0007521]; negative regulation of gene expression [GO:0010629]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of ossification [GO:0030279]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nephron tubule epithelial cell differentiation [GO:0072160]; neural crest cell differentiation [GO:0014033]; neuron development [GO:0048666]; neuron differentiation [GO:0030182]; osteoblast differentiation [GO:0001649]; outflow tract morphogenesis [GO:0003151]; platelet formation [GO:0030220]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of behavioral fear response [GO:2000987]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cardiac muscle cell differentiation [GO:2000727]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of macrophage apoptotic process [GO:2000111]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of skeletal muscle cell differentiation [GO:2001016]; positive regulation of skeletal muscle tissue development [GO:0048643]; positive regulation of transcription by RNA polymerase II [GO:0045944]; primary heart field specification [GO:0003138]; regulation of germinal center formation [GO:0002634]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of synaptic activity [GO:0060025]; regulation of transcription by RNA polymerase II [GO:0006357]; renal tubule morphogenesis [GO:0061333]; secondary heart field specification [GO:0003139]; sinoatrial valve morphogenesis [GO:0003185]; skeletal muscle tissue development [GO:0007519]; smooth muscle cell differentiation [GO:0051145]; ventricular cardiac muscle cell differentiation [GO:0055012] GO:0000122; GO:0000165; GO:0000976; GO:0000977; GO:0000978; GO:0000981; GO:0001228; GO:0001568; GO:0001649; GO:0001782; GO:0001947; GO:0001958; GO:0001974; GO:0002062; GO:0002467; GO:0002634; GO:0003138; GO:0003139; GO:0003151; GO:0003185; GO:0003211; GO:0003677; GO:0003700; GO:0005634; GO:0005737; GO:0006357; GO:0006959; GO:0007507; GO:0007519; GO:0007521; GO:0007611; GO:0010628; GO:0010629; GO:0010694; GO:0014033; GO:0016528; GO:0016607; GO:0030182; GO:0030220; GO:0030279; GO:0030318; GO:0030501; GO:0030890; GO:0032991; GO:0035051; GO:0035984; GO:0042100; GO:0043524; GO:0045652; GO:0045663; GO:0045666; GO:0045669; GO:0045893; GO:0045944; GO:0046983; GO:0048643; GO:0048666; GO:0050853; GO:0051145; GO:0055012; GO:0060025; GO:0060045; GO:0061333; GO:0071222; GO:0071277; GO:0071374; GO:0071466; GO:0071498; GO:0071560; GO:0072102; GO:0072160; GO:2000111; GO:2000727; GO:2000987; GO:2001013; GO:2001016 5452 XM_029356641.2 5 9 11 4 25 NA NA NA NA NA NA 5453 XM_029333293.2 86 41 0 149 199 NA NA NA NA NA NA 5454 XM_044327520.1 67 30 23 53 0 NA NA NA NA NA NA 5455 XM_029336978.2 267 214 122 192 176 Q97UU4 2.57e-25 Uncharacterized protein SSO2899 Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) NA NA 5456 XM_044320654.1 6 0 0 0 0 NA NA NA NA NA NA 5457 XM_044309318.1 29 0 0 0 104 NA NA NA NA NA NA 5458 XR_006395562.1 0 10 0 53 0 Q9UBN7 2.61e-66 Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-) Homo sapiens (Human) aggresome assembly [GO:0070842]; autophagy [GO:0006914]; axonal transport of mitochondrion [GO:0019896]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to misfolded protein [GO:0071218]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to topologically incorrect protein [GO:0035967]; cilium assembly [GO:0060271]; cilium disassembly [GO:0061523]; collateral sprouting [GO:0048668]; dendritic spine morphogenesis [GO:0060997]; epigenetic regulation of gene expression [GO:0040029]; histone deacetylation [GO:0016575]; Hsp90 deacetylation [GO:0070846]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of protein-containing complex disassembly [GO:0043242]; negative regulation of proteolysis [GO:0045861]; negative regulation of transcription by RNA polymerase II [GO:0000122]; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:0061734]; peptidyl-lysine deacetylation [GO:0034983]; polyubiquitinated misfolded protein transport [GO:0070845]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of hydrogen peroxide-mediated programmed cell death [GO:1901300]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of tubulin deacetylation [GO:0090044]; protein deacetylation [GO:0006476]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; protein-containing complex disassembly [GO:0032984]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of autophagy [GO:0010506]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of establishment of protein localization [GO:0070201]; regulation of fat cell differentiation [GO:0045598]; regulation of macroautophagy [GO:0016241]; regulation of microtubule-based movement [GO:0060632]; regulation of protein stability [GO:0031647]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]; response to dexamethasone [GO:0071548]; response to growth factor [GO:0070848]; response to immobilization stress [GO:0035902]; response to misfolded protein [GO:0051788]; tubulin deacetylation [GO:0090042]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] GO:0000118; GO:0000122; GO:0000209; GO:0000978; GO:0001222; GO:0001975; GO:0003779; GO:0004407; GO:0005634; GO:0005654; GO:0005737; GO:0005771; GO:0005813; GO:0005829; GO:0005874; GO:0005875; GO:0005901; GO:0006476; GO:0006515; GO:0006886; GO:0006914; GO:0007026; GO:0008013; GO:0008017; GO:0008270; GO:0010506; GO:0010634; GO:0010727; GO:0016234; GO:0016235; GO:0016241; GO:0016575; GO:0019896; GO:0019899; GO:0030424; GO:0030425; GO:0031252; GO:0031333; GO:0031593; GO:0031625; GO:0031647; GO:0031648; GO:0032418; GO:0032984; GO:0033138; GO:0033558; GO:0034983; GO:0035902; GO:0035967; GO:0036064; GO:0040029; GO:0042826; GO:0042903; GO:0043014; GO:0043130; GO:0043162; GO:0043204; GO:0043242; GO:0045598; GO:0045861; GO:0045892; GO:0048156; GO:0048471; GO:0048487; GO:0048668; GO:0048843; GO:0050775; GO:0051354; GO:0051412; GO:0051787; GO:0051788; GO:0051879; GO:0051968; GO:0060271; GO:0060632; GO:0060765; GO:0060997; GO:0061523; GO:0061734; GO:0070201; GO:0070301; GO:0070840; GO:0070842; GO:0070845; GO:0070846; GO:0070848; GO:0071218; GO:0071374; GO:0071548; GO:0090042; GO:0090044; GO:1901300; GO:1901984; GO:1903146; GO:1903223; GO:1904056; GO:1904115; GO:2000273 5459 XR_006395562.1 0 10 0 53 0 Q9UBN7 2.61e-66 Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-) Homo sapiens (Human) aggresome assembly [GO:0070842]; autophagy [GO:0006914]; axonal transport of mitochondrion [GO:0019896]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to misfolded protein [GO:0071218]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to topologically incorrect protein [GO:0035967]; cilium assembly [GO:0060271]; cilium disassembly [GO:0061523]; collateral sprouting [GO:0048668]; dendritic spine morphogenesis [GO:0060997]; epigenetic regulation of gene expression [GO:0040029]; histone deacetylation [GO:0016575]; Hsp90 deacetylation [GO:0070846]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of protein-containing complex disassembly [GO:0043242]; negative regulation of proteolysis [GO:0045861]; negative regulation of transcription by RNA polymerase II [GO:0000122]; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:0061734]; peptidyl-lysine deacetylation [GO:0034983]; polyubiquitinated misfolded protein transport [GO:0070845]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of hydrogen peroxide-mediated programmed cell death [GO:1901300]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of tubulin deacetylation [GO:0090044]; protein deacetylation [GO:0006476]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; protein-containing complex disassembly [GO:0032984]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of autophagy [GO:0010506]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of establishment of protein localization [GO:0070201]; regulation of fat cell differentiation [GO:0045598]; regulation of macroautophagy [GO:0016241]; regulation of microtubule-based movement [GO:0060632]; regulation of protein stability [GO:0031647]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]; response to dexamethasone [GO:0071548]; response to growth factor [GO:0070848]; response to immobilization stress [GO:0035902]; response to misfolded protein [GO:0051788]; tubulin deacetylation [GO:0090042]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] GO:0000118; GO:0000122; GO:0000209; GO:0000978; GO:0001222; GO:0001975; GO:0003779; GO:0004407; GO:0005634; GO:0005654; GO:0005737; GO:0005771; GO:0005813; GO:0005829; GO:0005874; GO:0005875; GO:0005901; GO:0006476; GO:0006515; GO:0006886; GO:0006914; GO:0007026; GO:0008013; GO:0008017; GO:0008270; GO:0010506; GO:0010634; GO:0010727; GO:0016234; GO:0016235; GO:0016241; GO:0016575; GO:0019896; GO:0019899; GO:0030424; GO:0030425; GO:0031252; GO:0031333; GO:0031593; GO:0031625; GO:0031647; GO:0031648; GO:0032418; GO:0032984; GO:0033138; GO:0033558; GO:0034983; GO:0035902; GO:0035967; GO:0036064; GO:0040029; GO:0042826; GO:0042903; GO:0043014; GO:0043130; GO:0043162; GO:0043204; GO:0043242; GO:0045598; GO:0045861; GO:0045892; GO:0048156; GO:0048471; GO:0048487; GO:0048668; GO:0048843; GO:0050775; GO:0051354; GO:0051412; GO:0051787; GO:0051788; GO:0051879; GO:0051968; GO:0060271; GO:0060632; GO:0060765; GO:0060997; GO:0061523; GO:0061734; GO:0070201; GO:0070301; GO:0070840; GO:0070842; GO:0070845; GO:0070846; GO:0070848; GO:0071218; GO:0071374; GO:0071548; GO:0090042; GO:0090044; GO:1901300; GO:1901984; GO:1903146; GO:1903223; GO:1904056; GO:1904115; GO:2000273 5460 XR_006395562.1 0 10 0 53 0 Q9UBN7 1.54e-60 Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-) Homo sapiens (Human) aggresome assembly [GO:0070842]; autophagy [GO:0006914]; axonal transport of mitochondrion [GO:0019896]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to misfolded protein [GO:0071218]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to topologically incorrect protein [GO:0035967]; cilium assembly [GO:0060271]; cilium disassembly [GO:0061523]; collateral sprouting [GO:0048668]; dendritic spine morphogenesis [GO:0060997]; epigenetic regulation of gene expression [GO:0040029]; histone deacetylation [GO:0016575]; Hsp90 deacetylation [GO:0070846]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of protein-containing complex disassembly [GO:0043242]; negative regulation of proteolysis [GO:0045861]; negative regulation of transcription by RNA polymerase II [GO:0000122]; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:0061734]; peptidyl-lysine deacetylation [GO:0034983]; polyubiquitinated misfolded protein transport [GO:0070845]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of hydrogen peroxide-mediated programmed cell death [GO:1901300]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of tubulin deacetylation [GO:0090044]; protein deacetylation [GO:0006476]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; protein-containing complex disassembly [GO:0032984]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of autophagy [GO:0010506]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of establishment of protein localization [GO:0070201]; regulation of fat cell differentiation [GO:0045598]; regulation of macroautophagy [GO:0016241]; regulation of microtubule-based movement [GO:0060632]; regulation of protein stability [GO:0031647]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]; response to dexamethasone [GO:0071548]; response to growth factor [GO:0070848]; response to immobilization stress [GO:0035902]; response to misfolded protein [GO:0051788]; tubulin deacetylation [GO:0090042]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] GO:0000118; GO:0000122; GO:0000209; GO:0000978; GO:0001222; GO:0001975; GO:0003779; GO:0004407; GO:0005634; GO:0005654; GO:0005737; GO:0005771; GO:0005813; GO:0005829; GO:0005874; GO:0005875; GO:0005901; GO:0006476; GO:0006515; GO:0006886; GO:0006914; GO:0007026; GO:0008013; GO:0008017; GO:0008270; GO:0010506; GO:0010634; GO:0010727; GO:0016234; GO:0016235; GO:0016241; GO:0016575; GO:0019896; GO:0019899; GO:0030424; GO:0030425; GO:0031252; GO:0031333; GO:0031593; GO:0031625; GO:0031647; GO:0031648; GO:0032418; GO:0032984; GO:0033138; GO:0033558; GO:0034983; GO:0035902; GO:0035967; GO:0036064; GO:0040029; GO:0042826; GO:0042903; GO:0043014; GO:0043130; GO:0043162; GO:0043204; GO:0043242; GO:0045598; GO:0045861; GO:0045892; GO:0048156; GO:0048471; GO:0048487; GO:0048668; GO:0048843; GO:0050775; GO:0051354; GO:0051412; GO:0051787; GO:0051788; GO:0051879; GO:0051968; GO:0060271; GO:0060632; GO:0060765; GO:0060997; GO:0061523; GO:0061734; GO:0070201; GO:0070301; GO:0070840; GO:0070842; GO:0070845; GO:0070846; GO:0070848; GO:0071218; GO:0071374; GO:0071548; GO:0090042; GO:0090044; GO:1901300; GO:1901984; GO:1903146; GO:1903223; GO:1904056; GO:1904115; GO:2000273 5461 XM_029330101.2 102 103 171 115 409 Q28107 2.76e-24 Coagulation factor V (Activated protein C cofactor) [Cleaved into: Coagulation factor V heavy chain; Coagulation factor V light chain] Bos taurus (Bovine) blood circulation [GO:0008015]; blood coagulation [GO:0007596] GO:0005507; GO:0005576; GO:0007596; GO:0008015; GO:0031091 5462 XM_029334102.2 35 0 87 203 253 Q96QU6 3.34e-90 1-aminocyclopropane-1-carboxylate synthase-like protein 1 (ACC synthase-like protein 1) Homo sapiens (Human) amino acid metabolic process [GO:0006520]; biosynthetic process [GO:0009058] GO:0006520; GO:0008483; GO:0009058; GO:0030170; GO:0042802 5463 XM_029339482.2 3971 1191 1978 1671 2991 Q91827 4.2e-23 Apoptosis regulator R1 (XR1) Xenopus laevis (African clawed frog) apoptotic process [GO:0006915]; regulation of apoptotic process [GO:0042981] GO:0006915; GO:0016020; GO:0042981 5464 XM_044313898.1 0 0 0 0 7 P61752 2.03e-28 Histamine H2 receptor (H2R) (HH2R) (Gastric receptor I) Pongo pygmaeus (Bornean orangutan) gastric acid secretion [GO:0001696]; positive regulation of vasoconstriction [GO:0045907] GO:0001696; GO:0004969; GO:0005886; GO:0045907 5465 XM_044313898.1 0 0 0 0 7 P61752 5.68e-26 Histamine H2 receptor (H2R) (HH2R) (Gastric receptor I) Pongo pygmaeus (Bornean orangutan) gastric acid secretion [GO:0001696]; positive regulation of vasoconstriction [GO:0045907] GO:0001696; GO:0004969; GO:0005886; GO:0045907 5466 XM_029343785.2 49 23 84 299 145 NA NA NA NA NA NA 5467 XM_044318635.1 0 106 68 31 67 NA NA NA NA NA NA 5468 XM_029352748.2 436 140 316 205 452 NA NA NA NA NA NA 5469 XM_044326822.1 24 47 6 27 10 NA NA NA NA NA NA 5470 XM_029358558.2 20 11 13 16 28 NA NA NA NA NA NA 5471 XM_029349308.2 1653 1265 1211 984 851 NA NA NA NA NA NA 5472 XM_029345661.2 0 4 0 0 22 NA NA NA NA NA NA 5473 XM_029351580.2 335 385 139 140 247 Q9NS73 8.24e-40 MAP3K12-binding inhibitory protein 1 (MAPK upstream kinase-binding inhibitory protein) (MUK-binding inhibitory protein) Homo sapiens (Human) histone H3 acetylation [GO:0043966]; histone H3-K14 acetylation [GO:0044154]; positive regulation of gene expression [GO:0010628]; positive regulation of JNK cascade [GO:0046330]; regulation of cell cycle [GO:0051726]; regulation of cell division [GO:0051302]; regulation of DNA-templated transcription [GO:0006355]; regulation of embryonic development [GO:0045995]; regulation of histone deacetylation [GO:0031063]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tubulin deacetylation [GO:0090043] GO:0004860; GO:0005654; GO:0005730; GO:0005829; GO:0006355; GO:0006357; GO:0010628; GO:0031063; GO:0042802; GO:0043966; GO:0044154; GO:0045995; GO:0046330; GO:0051302; GO:0051726; GO:0072686; GO:0090043; GO:0140672 5474 XM_029324228.2 13 1 15 2 20 NA NA NA NA NA NA 5475 XM_029352884.2 137 0 55 411 273 P46869 3.39e-59 Kinesin-like protein FLA10 (Protein KHP1) Chlamydomonas reinhardtii (Chlamydomonas smithii) intraciliary anterograde transport [GO:0035720]; motile cilium assembly [GO:0044458] GO:0003777; GO:0005524; GO:0005874; GO:0005929; GO:0008017; GO:0031514; GO:0035720; GO:0036064; GO:0044458; GO:0097014 5476 XM_044326853.1 16 0 0 0 3 NA NA NA NA NA NA 5477 XM_029335945.2 1 0 106 0 0 Q12767 2.39e-137 Transmembrane protein 94 Homo sapiens (Human) NA GO:0016020 5478 XM_029335945.2 1 0 106 0 0 Q12767 1.21e-32 Transmembrane protein 94 Homo sapiens (Human) NA GO:0016020 5479 XM_029337514.2 1059 1056 256 572 778 Q28955 3.59e-65 Protein N-terminal asparagine amidohydrolase (EC 3.5.1.121) (Protein NH2-terminal asparagine amidohydrolase) (PNAA) (Protein NH2-terminal asparagine deamidase) (PNAD) (Protein N-terminal Asn amidase) (Protein NTN-amidase) Sus scrofa (Pig) adult locomotory behavior [GO:0008344]; memory [GO:0007613]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0005634; GO:0005737; GO:0006511; GO:0007613; GO:0008344; GO:0008418 5480 XM_044329097.1 11 3 11 20 8 Q8K2J9 9.73e-72 BTB/POZ domain-containing protein 6 Mus musculus (Mouse) neurogenesis [GO:0022008] GO:0005829; GO:0022008 5481 XM_029348845.2 1141 784 677 893 968 Q96I34 6.55e-84 Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase-targeting subunit 3) Homo sapiens (Human) regulation of protein dephosphorylation [GO:0035304] GO:0005886; GO:0008157; GO:0017020; GO:0019888; GO:0035304 5482 XM_029353229.2 28 61 60 179 76 NA NA NA NA NA NA 5483 XM_044322221.1 247 422 229 174 52 Q5F499 0 Dynamin-like 120 kDa protein, mitochondrial (EC 3.6.5.5) (Optic atrophy protein 1 homolog) [Cleaved into: Dynamin-like 120 kDa protein, form S1] Gallus gallus (Chicken) apoptotic process [GO:0006915]; GTP metabolic process [GO:0046039]; membrane tubulation [GO:0097749]; mitochondrial fusion [GO:0008053] GO:0003924; GO:0005525; GO:0005737; GO:0005743; GO:0005758; GO:0005874; GO:0006915; GO:0008017; GO:0008053; GO:0016020; GO:0031966; GO:0046039; GO:0070300; GO:0097749; GO:1901612 5484 XM_029323645.2 2010 1219 1127 999 976 Q9V3L1 0 Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase) (Sulfateless) [Includes: Heparan sulfate N-deacetylase (EC 3.-.-.-); Heparan sulfate N-sulfotransferase (EC 2.8.2.-)] Drosophila melanogaster (Fruit fly) epithelial cell migration, open tracheal system [GO:0007427]; fibroblast growth factor receptor signaling pathway [GO:0008543]; glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0015014]; heparin biosynthetic process [GO:0030210]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing vein specification [GO:0007474]; mesoderm migration involved in gastrulation [GO:0007509]; regulation of imaginal disc growth [GO:0045570]; segment polarity determination [GO:0007367]; spermatogenesis [GO:0007283]; sulfur compound metabolic process [GO:0006790]; Wnt signaling pathway [GO:0016055] GO:0000137; GO:0000139; GO:0005783; GO:0005794; GO:0006024; GO:0006790; GO:0007283; GO:0007367; GO:0007427; GO:0007474; GO:0007509; GO:0008146; GO:0008543; GO:0008587; GO:0015012; GO:0015014; GO:0015016; GO:0016055; GO:0019213; GO:0030210; GO:0045570; GO:0102140 5485 XR_003826874.2 134 113 147 149 130 NA NA NA NA NA NA 5486 XM_029341641.2 587 313 250 418 426 Q5R8I2 1.23e-81 RNA transcription, translation and transport factor protein Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) negative regulation of protein kinase activity [GO:0006469]; positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388] GO:0000993; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0005829; GO:0006388; GO:0006469; GO:0042802; GO:0045944; GO:0048471; GO:0072669; GO:0072686 5487 XM_029334170.2 5 0 21 0 0 P25931 7.23e-34 RYamide receptor (Neuropeptide Y-like receptor) (NPY-R) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218] GO:0001653; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0016020 5488 XM_044326065.1 62 8 12 19 0 NA NA NA NA NA NA 5489 XR_006394149.1 67 30 43 110 112 NA NA NA NA NA NA 5490 XM_029351729.2 3759 3608 1422 2121 2456 NA NA NA NA NA NA 5491 XM_044325182.1 26 4 7 1 52 NA NA NA NA NA NA 5492 XM_044316790.1 55 16 59 69 46 Q1LZE9 2.3e-31 Serine protease 23 (EC 3.4.21.-) Bos taurus (Bovine) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0005634; GO:0006508 5493 XM_029333814.2 3192 2492 1274 1707 2379 P97363 0 Serine palmitoyltransferase 2 (EC 2.3.1.50) (Long chain base biosynthesis protein 2) (LCB 2) (Long chain base biosynthesis protein 2a) (LCB2a) (Serine-palmitoyl-CoA transferase 2) (SPT 2) Mus musculus (Mouse) adipose tissue development [GO:0060612]; ceramide biosynthetic process [GO:0046513]; lipophagy [GO:0061724]; positive regulation of lipophagy [GO:1904504]; sphinganine biosynthetic process [GO:0046511]; sphingolipid biosynthetic process [GO:0030148]; sphingomyelin biosynthetic process [GO:0006686]; sphingosine biosynthetic process [GO:0046512] GO:0004758; GO:0005739; GO:0005789; GO:0006686; GO:0017059; GO:0030148; GO:0030170; GO:0046511; GO:0046512; GO:0046513; GO:0060612; GO:0061724; GO:1904504 5494 XM_044329078.1 0 8 0 7 8 NA NA NA NA NA NA 5495 XM_044323124.1 51 11 19 13 9 NA NA NA NA NA NA 5496 XM_044315234.1 35 35 22 60 32 Q7ZYL5 7.85e-136 Kinesin-like protein KIF22-B (Chromokinesin kid-B) (Xkid-B) Xenopus laevis (African clawed frog) microtubule-based movement [GO:0007018] GO:0003677; GO:0003777; GO:0005524; GO:0005634; GO:0005737; GO:0005874; GO:0007018; GO:0008017 5497 XR_003826948.2 29 18 37 81 124 NA NA NA NA NA NA 5498 XM_044322325.1 0 0 52 0 1 NA NA NA NA NA NA 5499 XM_044322204.1 1264 1174 759 1068 890 Q99549 1.07e-33 M-phase phosphoprotein 8 (Two hybrid-associated protein 3 with RanBPM) (Twa3) Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; positive regulation of DNA methylation-dependent heterochromatin formation [GO:0090309]; regulation of DNA methylation [GO:0044030] GO:0000786; GO:0000792; GO:0003682; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0005886; GO:0035064; GO:0044030; GO:0045814; GO:0045869; GO:0045892; GO:0090309 5500 XM_029342246.2 243 483 619 133 370 O88898 9.93e-58 Tumor protein 63 (p63) (Transformation-related protein 63) (TP63) (Tumor protein p73-like) (p73L) Mus musculus (Mouse) anatomical structure formation involved in morphogenesis [GO:0048646]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular senescence [GO:0090398]; chromatin remodeling [GO:0006338]; cloacal septation [GO:0060197]; cranial skeletal system development [GO:1904888]; ectoderm and mesoderm interaction [GO:0007499]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; epidermal cell differentiation [GO:0009913]; epidermal cell division [GO:0010481]; epidermis development [GO:0008544]; epithelial cell development [GO:0002064]; epithelial cell differentiation [GO:0030855]; establishment of planar polarity [GO:0001736]; establishment of skin barrier [GO:0061436]; female genitalia morphogenesis [GO:0048807]; hair follicle development [GO:0001942]; hair follicle morphogenesis [GO:0031069]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; keratinocyte differentiation [GO:0030216]; keratinocyte proliferation [GO:0043616]; morphogenesis of a polarized epithelium [GO:0001738]; multicellular organism aging [GO:0010259]; negative regulation of cellular senescence [GO:2000773]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of keratinocyte differentiation [GO:0045617]; negative regulation of mesoderm development [GO:2000381]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron apoptotic process [GO:0051402]; Notch signaling pathway [GO:0007219]; odontogenesis of dentin-containing tooth [GO:0042475]; pattern specification process [GO:0007389]; polarized epithelial cell differentiation [GO:0030859]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cell cycle G1/S phase transition [GO:1902808]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of fibroblast apoptotic process [GO:2000271]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of somatic stem cell population maintenance [GO:1904674]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; prostate gland development [GO:0030850]; prostatic bud formation [GO:0060513]; protein tetramerization [GO:0051262]; proximal/distal pattern formation [GO:0009954]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of epidermal cell division [GO:0010482]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal system development [GO:0001501]; skin epidermis development [GO:0098773]; skin morphogenesis [GO:0043589]; spermatogenesis [GO:0007283]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; stem cell differentiation [GO:0048863]; stem cell proliferation [GO:0072089]; sympathetic nervous system development [GO:0048485]; transcription by RNA polymerase II [GO:0006366] GO:0000122; GO:0000785; GO:0000977; GO:0000978; GO:0000981; GO:0001228; GO:0001501; GO:0001736; GO:0001738; GO:0001942; GO:0002039; GO:0002064; GO:0003677; GO:0003682; GO:0003684; GO:0003690; GO:0003700; GO:0005634; GO:0005654; GO:0005737; GO:0005791; GO:0006338; GO:0006357; GO:0006366; GO:0006915; GO:0006974; GO:0007219; GO:0007283; GO:0007389; GO:0007499; GO:0008284; GO:0008544; GO:0009887; GO:0009913; GO:0009954; GO:0010259; GO:0010481; GO:0010482; GO:0010838; GO:0019904; GO:0030216; GO:0030326; GO:0030425; GO:0030850; GO:0030855; GO:0030859; GO:0031069; GO:0032991; GO:0033147; GO:0035115; GO:0035116; GO:0036342; GO:0042475; GO:0042771; GO:0042802; GO:0043005; GO:0043281; GO:0043565; GO:0043589; GO:0043616; GO:0045617; GO:0045669; GO:0045747; GO:0045892; GO:0045893; GO:0045944; GO:0046872; GO:0048485; GO:0048646; GO:0048807; GO:0048863; GO:0050699; GO:0051262; GO:0051402; GO:0060197; GO:0060513; GO:0060529; GO:0061436; GO:0072089; GO:0090398; GO:0097371; GO:0098773; GO:1902808; GO:1904674; GO:1904888; GO:2000271; GO:2000381; GO:2000648; GO:2000773; GO:2001235 5501 XM_029357830.2 1251 891 749 1414 1370 Q3ULF4 0 Paraplegin (EC 3.4.24.-) (Spastic paraplegia 7 protein) Mus musculus (Mouse) anterograde axonal transport [GO:0008089]; cell adhesion [GO:0007155]; mitochondrial outer membrane permeabilization involved in programmed cell death [GO:1902686]; mitochondrial protein processing [GO:0034982]; mitochondrion organization [GO:0007005]; regulation of cell adhesion [GO:0030155]; regulation of mitochondrial membrane permeability [GO:0046902] GO:0004176; GO:0004222; GO:0005524; GO:0005739; GO:0005743; GO:0005745; GO:0005757; GO:0007005; GO:0007155; GO:0008089; GO:0008270; GO:0016887; GO:0030155; GO:0034982; GO:0046902; GO:1902686; GO:1904115 5502 XM_044328825.1 0 0 1 0 11 NA NA NA NA NA NA 5503 XM_029351878.2 463 347 587 832 870 P14629 1.09e-85 DNA excision repair protein ERCC-5 homolog (EC 3.1.-.-) (DNA repair protein complementing XP-G cells homolog) (Xeroderma pigmentosum group G-complementing protein homolog) Xenopus laevis (African clawed frog) nucleotide-excision repair [GO:0006289] GO:0003697; GO:0004519; GO:0005634; GO:0005694; GO:0006289; GO:0046872 5504 XM_029351878.2 463 347 587 832 870 P14629 8.38e-59 DNA excision repair protein ERCC-5 homolog (EC 3.1.-.-) (DNA repair protein complementing XP-G cells homolog) (Xeroderma pigmentosum group G-complementing protein homolog) Xenopus laevis (African clawed frog) nucleotide-excision repair [GO:0006289] GO:0003697; GO:0004519; GO:0005634; GO:0005694; GO:0006289; GO:0046872 5505 XM_044321503.1 146 379 54 198 372 NA NA NA NA NA NA 5506 XM_029344056.2 4 0 0 0 12 NA NA NA NA NA NA 5507 XR_006394025.1 19 43 25 0 93 NA NA NA NA NA NA 5508 XR_003825884.2 82 87 8 59 45 NA NA NA NA NA NA 5509 XM_029357085.2 340 189 193 342 691 Q75WS4 0 Cryptochrome DASH Xenopus laevis (African clawed frog) DNA repair [GO:0006281] GO:0003913; GO:0006281 5510 XM_029358585.2 61 0 0 0 0 Q6DIJ4 6.51e-109 Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.4.19.12) (Deubiquitinating enzyme 10) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) autophagy [GO:0006914]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to interleukin-1 [GO:0071347]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA repair [GO:0006281]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; protein deubiquitination [GO:0016579]; regulation of autophagy [GO:0010506]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0002039; GO:0004197; GO:0004843; GO:0005634; GO:0005737; GO:0005769; GO:0006281; GO:0006511; GO:0006914; GO:0006974; GO:0010506; GO:0016579; GO:0030330; GO:0043124; GO:0044325; GO:0071347 5511 XM_044308759.1 0 43 24 104 0 NA NA NA NA NA NA 5512 XM_044325940.1 6 0 0 0 9 NA NA NA NA NA NA 5513 XM_029339602.2 6 0 0 0 28 Q9W676 2.36e-129 LIM domain-binding protein 2 (LDB-2) (Carboxyl-terminal LIM domain-binding protein 1) (CLIM-1) (LIM domain-binding factor CLIM1) (cLdb2) Gallus gallus (Chicken) negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000122; GO:0005634; GO:0005667; GO:0007399; GO:0030274; GO:0045944 5514 XR_006396319.1 527 387 229 177 418 Q8NCC3 7.46e-83 Phospholipase A2 group XV (1-O-acylceramide synthase) (ACS) (LCAT-like lysophospholipase) (LLPL) (EC 3.1.1.5) (Lysophospholipase 3) (Lysosomal phospholipase A and acyltransferase) (EC 2.3.1.-, EC 3.1.1.32, EC 3.1.1.4) (Lysosomal phospholipase A2) (LPLA2) Homo sapiens (Human) ceramide metabolic process [GO:0006672]; diacylglycerol biosynthetic process [GO:0006651]; fatty acid catabolic process [GO:0009062]; glycerophospholipid metabolic process [GO:0006650]; lipid metabolic process [GO:0006629]; phosphatidylcholine catabolic process [GO:0034638]; phosphatidylcholine metabolic process [GO:0046470]; phosphatidylethanolamine catabolic process [GO:0046338]; phosphatidylglycerol metabolic process [GO:0046471]; phosphatidylserine metabolic process [GO:0006658]; phospholipid metabolic process [GO:0006644] GO:0004622; GO:0005543; GO:0005576; GO:0005615; GO:0005654; GO:0005764; GO:0006629; GO:0006644; GO:0006650; GO:0006651; GO:0006658; GO:0006672; GO:0008270; GO:0008374; GO:0008970; GO:0009062; GO:0016020; GO:0016411; GO:0034638; GO:0043231; GO:0046338; GO:0046470; GO:0046471; GO:0047499; GO:0052739; GO:0052740; GO:0070062; GO:0102545 5515 XM_044319093.1 575 392 232 789 421 F4KGU4 0 ATP-dependent RNA helicase DEAH12, chloroplastic (EC 3.6.4.13) Arabidopsis thaliana (Mouse-ear cress) NA GO:0003723; GO:0003724; GO:0005524; GO:0009507; GO:0016740; GO:0016887; GO:0046872; GO:0140096 5516 XM_044314580.1 308 125 39 138 191 NA NA NA NA NA NA 5517 XM_044313141.1 0 16 21 14 14 P18130 3.58e-31 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) Bos taurus (Bovine) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of vasoconstriction [GO:0045907]; regulation of cardiac muscle contraction [GO:0055117] GO:0001996; GO:0004930; GO:0004937; GO:0005634; GO:0005737; GO:0005886; GO:0005901; GO:0007200; GO:0007204; GO:0007267; GO:0031965; GO:0043410; GO:0045907; GO:0046982; GO:0055117; GO:0071880 5518 XM_029344990.2 5 0 34 38 14 NA NA NA NA NA NA 5519 XM_029336982.2 4022 4526 963 3442 623 NA NA NA NA NA NA 5520 XM_029333495.2 15473 17326 10575 16098 10404 NA NA NA NA NA NA 5521 XM_029349297.2 0 0 70 0 74 NA NA NA NA NA NA 5522 XM_029328585.2 0 0 0 3 9 P35348 3.84e-36 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) (Alpha-adrenergic receptor 1c) Homo sapiens (Human) activation of phospholipase C activity [GO:0007202]; adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; adult heart development [GO:0007512]; aging [GO:0007568]; apoptotic process [GO:0006915]; calcium ion transport into cytosol [GO:0060402]; cell growth involved in cardiac muscle cell development [GO:0061049]; cell-cell signaling [GO:0007267]; G protein-coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; micturition [GO:0060073]; multicellular organism aging [GO:0010259]; negative regulation of autophagy [GO:0010507]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure [GO:0001985]; negative regulation of Rho protein signal transduction [GO:0035024]; neuron-glial cell signaling [GO:0150099]; norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001994]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; pilomotor reflex [GO:0097195]; positive regulation of action potential [GO:0045760]; positive regulation of cardiac muscle contraction [GO:0060452]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; positive regulation of systemic arterial blood pressure [GO:0003084]; positive regulation of the force of heart contraction by epinephrine-norepinephrine [GO:0001997]; positive regulation of vasoconstriction [GO:0045907]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; response to hormone [GO:0009725]; response to xenobiotic stimulus [GO:0009410]; signal transduction [GO:0007165]; smooth muscle contraction [GO:0006939] GO:0000165; GO:0001985; GO:0001994; GO:0001996; GO:0001997; GO:0003084; GO:0004930; GO:0004937; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0005901; GO:0006915; GO:0006939; GO:0007165; GO:0007186; GO:0007200; GO:0007202; GO:0007204; GO:0007267; GO:0007512; GO:0007568; GO:0008285; GO:0009410; GO:0009725; GO:0010259; GO:0010507; GO:0010613; GO:0030018; GO:0030315; GO:0031965; GO:0032230; GO:0035024; GO:0035556; GO:0042734; GO:0043231; GO:0043410; GO:0045211; GO:0045760; GO:0045907; GO:0045987; GO:0046982; GO:0060073; GO:0060402; GO:0060452; GO:0061049; GO:0070374; GO:0071880; GO:0090037; GO:0097195; GO:0098691; GO:0098978; GO:0098982; GO:0099171; GO:0150099; GO:1903997 5523 XM_029331383.2 204 0 180 70 240 D3YXG0 1.23e-72 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 5524 XM_029331383.2 204 0 180 70 240 D3YXG0 2.29e-63 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 5525 XR_006395535.1 0 40 16 59 4 P53992 0 Protein transport protein Sec24C (SEC24-related protein C) Homo sapiens (Human) COPII-coated vesicle cargo loading [GO:0090110]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; in utero embryonic development [GO:0001701]; intracellular protein transport [GO:0006886] GO:0000149; GO:0001701; GO:0005789; GO:0005829; GO:0006886; GO:0006888; GO:0008270; GO:0012507; GO:0030127; GO:0070971; GO:0090110 5526 XM_029332216.2 48 34 30 200 120 Q9Y5X5 3.26e-40 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (G-protein coupled receptor HLWAR77) (Neuropeptide G-protein coupled receptor) Homo sapiens (Human) detection of abiotic stimulus [GO:0009582]; G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0009582; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 5527 XM_029330041.2 831 568 364 546 540 A8WIP6 0 Cyclin-dependent kinase 20 (EC 2.7.11.22) (Cell cycle-related kinase) (Cell division protein kinase 20) Danio rerio (Zebrafish) (Brachydanio rerio) cell cycle [GO:0007049]; cell division [GO:0051301]; cilium assembly [GO:0060271]; protein phosphorylation [GO:0006468] GO:0004693; GO:0005524; GO:0005634; GO:0005737; GO:0005929; GO:0006468; GO:0007049; GO:0051301; GO:0060271; GO:0106310 5528 XM_044321347.1 0 0 0 6 2 NA NA NA NA NA NA 5529 XR_006396033.1 10 0 0 15 0 NA NA NA NA NA NA 5530 XR_006397793.1 42 30 13 16 29 NA NA NA NA NA NA 5531 XR_006393892.1 41 2 25 5 151 NA NA NA NA NA NA 5532 XM_029324579.2 2717 1524 1278 2120 2825 P09623 0 Dihydrolipoyl dehydrogenase, mitochondrial (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase) Sus scrofa (Pig) histone succinylation [GO:0106077] GO:0001669; GO:0004148; GO:0005634; GO:0005739; GO:0005759; GO:0031514; GO:0045252; GO:0050660; GO:0106077 5533 XM_044319141.1 133 60 130 251 99 NA NA NA NA NA NA 5534 XR_006396689.1 44 16 3 54 19 NA NA NA NA NA NA 5535 XM_029341142.2 489 493 688 683 1610 P21802 2.7e-149 Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332) Homo sapiens (Human) angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell fate commitment [GO:0045165]; cell-cell signaling [GO:0007267]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; lung-associated mesenchyme development [GO:0060484]; mammary gland bud formation [GO:0060615]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smooth muscle cell differentiation [GO:0051150]; regulation of smoothened signaling pathway [GO:0008589]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060] GO:0000122; GO:0001525; GO:0001657; GO:0001701; GO:0001837; GO:0002053; GO:0003148; GO:0003149; GO:0003416; GO:0004713; GO:0004714; GO:0005007; GO:0005524; GO:0005576; GO:0005634; GO:0005737; GO:0005794; GO:0005886; GO:0005938; GO:0006915; GO:0007169; GO:0007267; GO:0007409; GO:0008201; GO:0008284; GO:0008543; GO:0008589; GO:0009791; GO:0009880; GO:0009887; GO:0009986; GO:0010518; GO:0010839; GO:0016020; GO:0016331; GO:0017134; GO:0018108; GO:0021769; GO:0021847; GO:0021860; GO:0022612; GO:0030177; GO:0030282; GO:0030324; GO:0030855; GO:0030901; GO:0030916; GO:0031069; GO:0031410; GO:0032496; GO:0032808; GO:0033674; GO:0033688; GO:0035265; GO:0035602; GO:0035603; GO:0035604; GO:0035607; GO:0042060; GO:0042472; GO:0042476; GO:0042802; GO:0042803; GO:0043235; GO:0043410; GO:0045165; GO:0045471; GO:0045667; GO:0045787; GO:0045944; GO:0046777; GO:0048286; GO:0048333; GO:0048557; GO:0048562; GO:0048565; GO:0048568; GO:0048608; GO:0048661; GO:0048701; GO:0048705; GO:0048730; GO:0048755; GO:0048762; GO:0050679; GO:0051150; GO:0051781; GO:0055010; GO:0060045; GO:0060076; GO:0060174; GO:0060348; GO:0060349; GO:0060442; GO:0060445; GO:0060449; GO:0060463; GO:0060484; GO:0060501; GO:0060512; GO:0060523; GO:0060527; GO:0060529; GO:0060595; GO:0060601; GO:0060615; GO:0060664; GO:0060667; GO:0060670; GO:0060688; GO:0060915; GO:0060916; GO:0070372; GO:0070374; GO:0071300; GO:0071560; GO:0090263 5536 XM_044319177.1 153 0 0 113 0 A6QLU6 3.87e-63 Adhesion G-protein coupled receptor D1 (G-protein coupled receptor 133) Bos taurus (Bovine) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0005886; GO:0007166; GO:0007186; GO:0007189 5537 XM_029348187.2 2040 1043 1572 2004 1252 Q6P7A2 0 Ubiquitin conjugation factor E4 A (EC 2.3.2.27) (RING-type E3 ubiquitin transferase E4 A) Rattus norvegicus (Rat) protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0000151; GO:0000209; GO:0005634; GO:0005737; GO:0016567; GO:0030433; GO:0034450; GO:0061630 5538 XM_044313311.1 17 8 0 1 69 NA NA NA NA NA NA 5539 XR_006395783.1 65 47 0 41 22 NA NA NA NA NA NA 5540 XM_044323629.1 1 0 6 7 12 NA NA NA NA NA NA 5541 XM_029356391.2 738 457 392 467 746 Q9P241 0 Phospholipid-transporting ATPase VD (EC 7.6.2.1) (ATPase class V type 10D) (P4-ATPase flippase complex alpha subunit ATP10D) Homo sapiens (Human) cation transport [GO:0006812]; ion transmembrane transport [GO:0034220]; phospholipid translocation [GO:0045332] GO:0000287; GO:0005524; GO:0005654; GO:0005783; GO:0005789; GO:0005886; GO:0006812; GO:0016020; GO:0016887; GO:0034220; GO:0045332; GO:0140326; GO:0140351; GO:1990531 5542 XM_044328144.1 132 111 94 150 272 NA NA NA NA NA NA 5543 XM_029324200.2 1402 990 754 1438 1597 Q5RFQ3 0 Periodic tryptophan protein 2 homolog Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0005730 5544 XM_044308311.1 100 24 23 21 33 Q9N126 5.46e-69 Retinol dehydrogenase 8 (EC 1.1.1.300) (Photoreceptor outer segment all-trans retinol dehydrogenase) Bos taurus (Bovine) estrogen biosynthetic process [GO:0006703]; response to stimulus [GO:0050896]; retinol metabolic process [GO:0042572]; visual perception [GO:0007601] GO:0004303; GO:0004745; GO:0005829; GO:0006703; GO:0007601; GO:0016491; GO:0042572; GO:0042622; GO:0050896; GO:0052650 5545 XM_044313636.1 0 886 445 522 306 NA NA NA NA NA NA 5546 XM_029328654.2 0 24 95 89 76 Q5R6J1 3.86e-88 Sodium-dependent neutral amino acid transporter B(0)AT1 (Solute carrier family 6 member 19) (System B(0) neutral amino acid transporter AT1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0015175; GO:0015293; GO:0016324 5547 XM_029341998.2 25 0 2 1 5 NA NA NA NA NA NA 5548 XR_003824452.2 0 0 31 0 0 NA NA NA NA NA NA 5549 XM_029346750.2 1106 374 575 1710 2428 NA NA NA NA NA NA 5550 XM_029357851.2 473 301 272 188 676 A6QLU6 7.32e-75 Adhesion G-protein coupled receptor D1 (G-protein coupled receptor 133) Bos taurus (Bovine) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0005886; GO:0007166; GO:0007186; GO:0007189 5551 XR_006396032.1 6 0 8 35 73 NA NA NA NA NA NA 5552 XM_044307630.1 28 5728 633 1639 2347 NA NA NA NA NA NA 5553 XM_029358301.2 439 488 0 673 3 Q9QYS2 0 Metabotropic glutamate receptor 3 (mGluR3) Mus musculus (Mouse) G protein-coupled glutamate receptor signaling pathway [GO:0007216]; gene expression [GO:0010467]; modulation of chemical synaptic transmission [GO:0050804]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; regulation of sensory perception of pain [GO:0051930]; regulation of synaptic transmission, glutamatergic [GO:0051966]; sensory perception of pain [GO:0019233]; synaptic transmission, glutamatergic [GO:0035249] GO:0001640; GO:0001641; GO:0005246; GO:0005886; GO:0007216; GO:0010467; GO:0014069; GO:0019233; GO:0030424; GO:0035249; GO:0042734; GO:0043005; GO:0043197; GO:0045211; GO:0048786; GO:0050804; GO:0051930; GO:0051966; GO:0097110; GO:0097449; GO:0098978; GO:0099170 5554 XM_029346494.2 294 263 130 280 265 Q9ER88 1.51e-67 28S ribosomal protein S29, mitochondrial (MRP-S29) (S29mt) (Death-associated protein 3) (DAP-3) Mus musculus (Mouse) apoptotic mitochondrial changes [GO:0008637]; mitochondrial translation [GO:0032543] GO:0003735; GO:0005654; GO:0005739; GO:0005743; GO:0005759; GO:0005763; GO:0008637; GO:0032543 5555 XM_029331123.2 33 30 19 35 39 Q9UHC6 5.41e-36 Contactin-associated protein-like 2 (Cell recognition molecule Caspr2) Homo sapiens (Human) adult behavior [GO:0030534]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell population proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; clustering of voltage-gated potassium channels [GO:0045163]; learning [GO:0007612]; limbic system development [GO:0021761]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuron recognition [GO:0008038]; positive regulation of gap junction assembly [GO:1903598]; protein localization to juxtaparanode region of axon [GO:0071205]; social behavior [GO:0035176]; striatum development [GO:0021756]; superior temporal gyrus development [GO:0071109]; thalamus development [GO:0021794]; transmission of nerve impulse [GO:0019226]; vocal learning [GO:0042297]; vocalization behavior [GO:0071625] GO:0005769; GO:0005794; GO:0007155; GO:0007420; GO:0007612; GO:0008038; GO:0008076; GO:0008283; GO:0009986; GO:0016020; GO:0019226; GO:0019899; GO:0021756; GO:0021761; GO:0021794; GO:0021987; GO:0030424; GO:0030425; GO:0030534; GO:0030673; GO:0031175; GO:0033010; GO:0035176; GO:0042297; GO:0043025; GO:0043204; GO:0044224; GO:0045163; GO:0048812; GO:0071109; GO:0071205; GO:0071625; GO:1903598 5556 XM_029336997.2 37 55 57 44 227 Q94887 1.67e-34 Neurexin-4 (Neurexin IV) Drosophila melanogaster (Fruit fly) axon ensheathment [GO:0008366]; cell adhesion involved in heart morphogenesis [GO:0061343]; cell-cell junction organization [GO:0045216]; dorsal closure [GO:0007391]; establishment of glial blood-brain barrier [GO:0060857]; heart process [GO:0003015]; nerve maturation [GO:0021682]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]; synaptic target recognition [GO:0008039]; terminal button organization [GO:0072553] GO:0003015; GO:0005886; GO:0005919; GO:0007391; GO:0008039; GO:0008104; GO:0008366; GO:0019991; GO:0021682; GO:0035151; GO:0045202; GO:0045216; GO:0048786; GO:0060857; GO:0061343; GO:0072553; GO:0097105 5557 XM_044313782.1 24 28 0 168 97 NA NA NA NA NA NA 5558 XM_029334684.2 6649 6624 2814 5261 4272 Q9H8M1 3.01e-67 Coenzyme Q-binding protein COQ10 homolog B, mitochondrial Homo sapiens (Human) cellular respiration [GO:0045333]; ubiquinone biosynthetic process [GO:0006744] GO:0005739; GO:0005743; GO:0006744; GO:0045333; GO:0048039 5559 XM_029333835.2 850 1270 438 916 771 A4IHR1 0 Tetratricopeptide repeat protein 30A (TPR repeat protein 30A) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) intraciliary transport [GO:0042073]; protein polyglutamylation [GO:0018095] GO:0005879; GO:0005929; GO:0018095; GO:0042073 5560 XM_044327069.1 0 0 4 0 24 P35067 1.09e-81 Histone H2B Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 5561 XM_029357781.2 39 0 34 0 89 NA NA NA NA NA NA 5562 XM_044308762.1 0 0 112 0 285 Q9H583 0 HEAT repeat-containing protein 1 (Protein BAP28) (U3 small nucleolar RNA-associated protein 10 homolog) [Cleaved into: HEAT repeat-containing protein 1, N-terminally processed] Homo sapiens (Human) maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; positive regulation of rRNA processing [GO:2000234]; positive regulation of transcription by RNA polymerase I [GO:0045943] GO:0000462; GO:0001650; GO:0003723; GO:0005654; GO:0005730; GO:0005739; GO:0016020; GO:0030515; GO:0030686; GO:0032040; GO:0034455; GO:0045943; GO:2000234 5563 XR_006391318.1 0 5 16 0 0 NA NA NA NA NA NA 5564 XM_044318496.1 359 657 105 1424 103 Q9ULT8 0 E3 ubiquitin-protein ligase HECTD1 (EC 2.3.2.26) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1) Homo sapiens (Human) anatomical structure development [GO:0048856]; aorta development [GO:0035904]; heart valve development [GO:0003170]; natural killer cell differentiation [GO:0001779]; negative regulation of protein localization to plasma membrane [GO:1903077]; neural tube closure [GO:0001843]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein localization to plasma membrane [GO:0072659]; protein polyubiquitination [GO:0000209]; spongiotrophoblast differentiation [GO:0060708]; trophoblast giant cell differentiation [GO:0060707]; ventricular septum development [GO:0003281] GO:0000209; GO:0001779; GO:0001843; GO:0003170; GO:0003281; GO:0016607; GO:0032436; GO:0035904; GO:0043161; GO:0046872; GO:0048856; GO:0051865; GO:0060707; GO:0060708; GO:0061630; GO:0070534; GO:0072659; GO:1903077 5565 XM_044318496.1 359 657 105 1424 103 Q9ULT8 2.07e-164 E3 ubiquitin-protein ligase HECTD1 (EC 2.3.2.26) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1) Homo sapiens (Human) anatomical structure development [GO:0048856]; aorta development [GO:0035904]; heart valve development [GO:0003170]; natural killer cell differentiation [GO:0001779]; negative regulation of protein localization to plasma membrane [GO:1903077]; neural tube closure [GO:0001843]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein localization to plasma membrane [GO:0072659]; protein polyubiquitination [GO:0000209]; spongiotrophoblast differentiation [GO:0060708]; trophoblast giant cell differentiation [GO:0060707]; ventricular septum development [GO:0003281] GO:0000209; GO:0001779; GO:0001843; GO:0003170; GO:0003281; GO:0016607; GO:0032436; GO:0035904; GO:0043161; GO:0046872; GO:0048856; GO:0051865; GO:0060707; GO:0060708; GO:0061630; GO:0070534; GO:0072659; GO:1903077 5566 XM_044318496.1 359 657 105 1424 103 Q9ULT8 2.42e-103 E3 ubiquitin-protein ligase HECTD1 (EC 2.3.2.26) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1) Homo sapiens (Human) anatomical structure development [GO:0048856]; aorta development [GO:0035904]; heart valve development [GO:0003170]; natural killer cell differentiation [GO:0001779]; negative regulation of protein localization to plasma membrane [GO:1903077]; neural tube closure [GO:0001843]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein localization to plasma membrane [GO:0072659]; protein polyubiquitination [GO:0000209]; spongiotrophoblast differentiation [GO:0060708]; trophoblast giant cell differentiation [GO:0060707]; ventricular septum development [GO:0003281] GO:0000209; GO:0001779; GO:0001843; GO:0003170; GO:0003281; GO:0016607; GO:0032436; GO:0035904; GO:0043161; GO:0046872; GO:0048856; GO:0051865; GO:0060707; GO:0060708; GO:0061630; GO:0070534; GO:0072659; GO:1903077 5567 XM_029356647.2 9 4 4 4 4 NA NA NA NA NA NA 5568 XM_044323571.1 6 2 7 21 0 NA NA NA NA NA NA 5569 XM_029345245.2 24759 25677 18194 15991 6604 Q9XT54 3.23e-83 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (GMP-PDE delta) Canis lupus familiaris (Dog) (Canis familiaris) response to stimulus [GO:0050896]; visual perception [GO:0007601] GO:0005095; GO:0005737; GO:0005829; GO:0005856; GO:0007601; GO:0030659; GO:0031267; GO:0031410; GO:0042995; GO:0050896 5570 XM_029356420.2 0 0 17 0 34 NA NA NA NA NA NA 5571 XM_029348974.2 1362 1606 748 1188 1404 NA NA NA NA NA NA 5572 XM_044309062.1 16 0 5 0 19 Q3UQ28 5.74e-32 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 5573 XM_044309062.1 16 0 5 0 19 Q3UQ28 3.95e-29 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 5574 XM_044322885.1 116 98 18 172 154 B3EWY9 1.55e-51 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 5575 XM_044323201.1 42 0 0 0 0 O00463 4.28e-23 TNF receptor-associated factor 5 (RING finger protein 84) Homo sapiens (Human) apoptotic process [GO:0006915]; interleukin-17-mediated signaling pathway [GO:0097400]; mRNA stabilization [GO:0048255]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of JNK cascade [GO:0046330]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; signal transduction [GO:0007165]; signal transduction involved in regulation of gene expression [GO:0023019]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0005164; GO:0005813; GO:0005829; GO:0006915; GO:0007165; GO:0008270; GO:0008284; GO:0009898; GO:0023019; GO:0031625; GO:0031996; GO:0033209; GO:0035631; GO:0042802; GO:0042981; GO:0043122; GO:0043123; GO:0046330; GO:0048255; GO:0051091; GO:0051092; GO:0070534; GO:0097400 5576 XM_029351199.2 0 10 0 8 0 Q924V1 7.39e-129 NADPH oxidase 4 (EC 1.6.3.-) (Kidney oxidase-1) (KOX-1) (Kidney superoxide-producing NADPH oxidase) Rattus norvegicus (Rat) aging [GO:0007568]; bone resorption [GO:0045453]; cardiac muscle cell differentiation [GO:0055007]; cell morphogenesis [GO:0000902]; cellular response to cAMP [GO:0071320]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose stimulus [GO:0071333]; cellular response to transforming growth factor beta stimulus [GO:0071560]; defense response [GO:0006952]; gene expression [GO:0010467]; heart process [GO:0003015]; homocysteine metabolic process [GO:0050667]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hydrogen peroxide biosynthetic process [GO:0010729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of stress fiber assembly [GO:0051496]; reactive oxygen species metabolic process [GO:0072593]; response to hypoxia [GO:0001666]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801] GO:0000902; GO:0001666; GO:0003015; GO:0005634; GO:0005739; GO:0005789; GO:0005886; GO:0005925; GO:0006801; GO:0006952; GO:0007568; GO:0008285; GO:0010467; GO:0010729; GO:0014911; GO:0016174; GO:0016175; GO:0016324; GO:0042554; GO:0043020; GO:0043065; GO:0043406; GO:0045453; GO:0048471; GO:0050664; GO:0050667; GO:0051496; GO:0051897; GO:0055007; GO:0061098; GO:0070374; GO:0071320; GO:0071333; GO:0071480; GO:0071560; GO:0071944; GO:0072341; GO:0072593; GO:0097038; GO:1990782; GO:2000379; GO:2000573 5577 XM_029330546.2 171 0 38 108 43 Q8R368 4.71e-89 Dynein axonemal assembly factor 4 (Dyslexia susceptibility 1 candidate gene 1 protein homolog) Mus musculus (Mouse) cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; heart development [GO:0007507]; inner dynein arm assembly [GO:0036159]; learning or memory [GO:0007611]; neuron migration [GO:0001764]; outer dynein arm assembly [GO:0036158]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of proteasomal protein catabolic process [GO:0061136] GO:0001764; GO:0003341; GO:0003351; GO:0005576; GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0005886; GO:0007368; GO:0007507; GO:0007611; GO:0030331; GO:0033146; GO:0036158; GO:0036159; GO:0043005; GO:0051649; GO:0061136; GO:0097730; GO:0120293 5578 XM_029334541.2 3 0 0 8 9 NA NA NA NA NA NA 5579 XM_029344971.2 729 709 448 585 888 P50637 2.16e-42 Translocator protein (Mitochondrial benzodiazepine receptor) (PKBS) (Peripheral-type benzodiazepine receptor) (PBR) Mus musculus (Mouse) adrenal gland development [GO:0030325]; aging [GO:0007568]; behavioral response to pain [GO:0048266]; cellular hypotonic response [GO:0071476]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to zinc ion [GO:0071294]; chloride transport [GO:0006821]; cholesterol homeostasis [GO:0042632]; contact inhibition [GO:0060242]; establishment of protein localization to mitochondrion [GO:0072655]; glial cell migration [GO:0008347]; ion transport [GO:0006811]; lipid transport [GO:0006869]; maintenance of protein location in mitochondrion [GO:0072656]; negative regulation of ATP metabolic process [GO:1903579]; negative regulation of autophagy of mitochondrion [GO:1903147]; negative regulation of corticosterone secretion [GO:2000853]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of mitochondrion organization [GO:0010823]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of tumor necrosis factor production [GO:0032720]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of apoptotic process [GO:0043065]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of necrotic cell death [GO:0010940]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; regulation of steroid biosynthetic process [GO:0050810]; response to acetylcholine [GO:1905144]; response to manganese ion [GO:0010042]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]; response to vitamin B1 [GO:0010266]; response to xenobiotic stimulus [GO:0009410]; steroid biosynthetic process [GO:0006694] GO:0005497; GO:0005739; GO:0005741; GO:0005783; GO:0005829; GO:0006694; GO:0006811; GO:0006821; GO:0006869; GO:0007568; GO:0008347; GO:0008503; GO:0009410; GO:0010042; GO:0010266; GO:0010823; GO:0010940; GO:0014012; GO:0015485; GO:0016020; GO:0030325; GO:0031397; GO:0032570; GO:0032720; GO:0033574; GO:0042632; GO:0043065; GO:0043231; GO:0044325; GO:0045019; GO:0048266; GO:0050810; GO:0051901; GO:0051928; GO:0060242; GO:0060252; GO:0060253; GO:0071222; GO:0071294; GO:0071476; GO:0072655; GO:0072656; GO:1903147; GO:1903579; GO:1905144; GO:2000379; GO:2000853 5580 XM_044311814.1 0 2 0 9 21 NA NA NA NA NA NA 5581 XM_044314553.1 0 0 0 9 19 NA NA NA NA NA NA 5582 XM_029330295.2 209 3 48 139 106 P41247 8.82e-70 Patatin-like phospholipase domain-containing protein 4 (EC 3.1.1.3) (Calcium-independent phospholipase A2-eta) (iPLA2-eta) (EC 3.1.1.4) (Protein GS2) Homo sapiens (Human) lipid homeostasis [GO:0055088]; triglyceride catabolic process [GO:0019433] GO:0004623; GO:0004806; GO:0005737; GO:0005739; GO:0005811; GO:0005829; GO:0016020; GO:0016411; GO:0019433; GO:0047376; GO:0050253; GO:0051264; GO:0051265; GO:0055088 5583 XM_029357986.2 263 157 99 396 487 Q5ZLY5 2.53e-110 Pleckstrin homology domain-containing family F member 2 (PH domain-containing family F member 2) Gallus gallus (Chicken) endosome organization [GO:0007032]; endosome to lysosome transport [GO:0008333]; protein transport [GO:0015031] GO:0005769; GO:0005783; GO:0007032; GO:0008333; GO:0015031; GO:0031901; GO:0035091; GO:0046872 5584 XM_044325309.1 0 0 0 0 7 Q27084 1.27e-80 Tachylectin-2 (Lectin L10c) Tachypleus tridentatus (Japanese horseshoe crab) innate immune response [GO:0045087] GO:0005576; GO:0030246; GO:0045087 5585 XM_044325309.1 0 0 0 0 7 Q27084 8.85e-66 Tachylectin-2 (Lectin L10c) Tachypleus tridentatus (Japanese horseshoe crab) innate immune response [GO:0045087] GO:0005576; GO:0030246; GO:0045087 5586 XM_029332897.2 3112 2464 1620 4333 4357 NA NA NA NA NA NA 5587 XM_044315227.1 0 0 12 0 15 NA NA NA NA NA NA 5588 XM_029344263.2 4 0 0 16 20 NA NA NA NA NA NA 5589 XM_044314641.1 41 59 3 17 26 NA NA NA NA NA NA 5590 XR_006391928.1 66 68 59 95 53 NA NA NA NA NA NA 5591 XR_006396045.1 12 71 45 4 60 NA NA NA NA NA NA 5592 XM_029340523.2 35 22 7 31 32 NA NA NA NA NA NA 5593 XM_044312603.1 31 0 42 34 77 Q9HD40 0 O-phosphoseryl-tRNA(Sec) selenium transferase (EC 2.9.1.2) (Liver-pancreas antigen) (LP) (SLA-p35) (SLA/LP autoantigen) (Selenocysteine synthase) (Sec synthase) (Selenocysteinyl-tRNA(Sec) synthase) (Sep-tRNA:Sec-tRNA synthase) (SepSecS) (Soluble liver antigen) (SLA) (UGA suppressor tRNA-associated protein) (tRNA(Ser/Sec)-associated antigenic protein) Homo sapiens (Human) selenocysteine incorporation [GO:0001514]; selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056] GO:0000049; GO:0001514; GO:0005634; GO:0005737; GO:0005829; GO:0097056; GO:0098621 5594 XM_044315674.1 0 7 0 0 8 NA NA NA NA NA NA 5595 XM_029334445.2 166 76 87 112 106 Q9VAU9 5.99e-112 Zinc finger protein 330 homolog (Nucleolar autoantigen 36 homolog) Drosophila melanogaster (Fruit fly) larval lymph gland hemopoiesis [GO:0035167] GO:0000775; GO:0005634; GO:0005730; GO:0008270; GO:0030496; GO:0035167 5596 XM_044317319.1 35 0 0 17 0 P63138 1.03e-57 Gamma-aminobutyric acid receptor subunit beta-2 (GABA(A) receptor subunit beta-2) Rattus norvegicus (Rat) cellular response to histamine [GO:0071420]; chemical synaptic transmission [GO:0007268]; chemical synaptic transmission, postsynaptic [GO:0099565]; chloride transmembrane transport [GO:1902476]; cochlea development [GO:0090102]; gamma-aminobutyric acid signaling pathway [GO:0007214]; inhibitory synapse assembly [GO:1904862]; inner ear receptor cell development [GO:0060119]; innervation [GO:0060384]; ion transmembrane transport [GO:0034220]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; nervous system process [GO:0050877]; neuron development [GO:0048666]; regulation of membrane potential [GO:0042391]; regulation of neuron apoptotic process [GO:0043523]; regulation of postsynaptic membrane potential [GO:0060078]; sensory perception of sound [GO:0007605]; signal transduction [GO:0007165]; synaptic transmission, GABAergic [GO:0051932] GO:0004890; GO:0005231; GO:0005237; GO:0005254; GO:0005829; GO:0005886; GO:0007165; GO:0007214; GO:0007268; GO:0007605; GO:0016020; GO:0022851; GO:0030594; GO:0030659; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0043523; GO:0043524; GO:0045202; GO:0048666; GO:0048787; GO:0050877; GO:0051932; GO:0060078; GO:0060119; GO:0060384; GO:0071420; GO:0090102; GO:0098978; GO:0098982; GO:0099507; GO:0099565; GO:0099634; GO:1901215; GO:1902476; GO:1902710; GO:1902711; GO:1904315; GO:1904862 5597 XM_044315663.1 2 0 0 7 6 NA NA NA NA NA NA 5598 XM_029350974.2 1111 672 551 437 423 NA NA NA NA NA NA 5599 XM_044320684.1 14 0 0 7 0 NA NA NA NA NA NA 5600 XM_029357292.2 1030 812 951 1172 1579 Q9BVK2 3.65e-156 Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase (EC 2.4.1.265) (Asparagine-linked glycosylation protein 8 homolog) (Dol-P-Glc:Glc(1)Man(9)GlcNAc(2)-PP-dolichyl alpha-1,3-glucosyltransferase) (Dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichyl glucosyltransferase) Homo sapiens (Human) dolichol-linked oligosaccharide biosynthetic process [GO:0006488]; oligosaccharide-lipid intermediate biosynthetic process [GO:0006490]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279] GO:0000033; GO:0004583; GO:0005789; GO:0006487; GO:0006488; GO:0006490; GO:0018279; GO:0042283 5601 XM_029349338.2 3 92 0 0 16 NA NA NA NA NA NA 5602 XM_044324469.1 15 4 20 20 10 NA NA NA NA NA NA 5603 XM_044306965.1 345 127 226 179 396 B3EWY9 0 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 5604 XR_006395099.1 1010 788 552 862 1046 NA NA NA NA NA NA 5605 XM_044321715.1 1021 349 322 1429 931 P35556 0 Fibrillin-2 [Cleaved into: Placensin] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030023; GO:0030326; GO:0030501; GO:0031012; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 5606 XM_044321715.1 1021 349 322 1429 931 P35556 0 Fibrillin-2 [Cleaved into: Placensin] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030023; GO:0030326; GO:0030501; GO:0031012; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 5607 XM_044321715.1 1021 349 322 1429 931 P35556 0 Fibrillin-2 [Cleaved into: Placensin] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030023; GO:0030326; GO:0030501; GO:0031012; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 5608 XM_044321715.1 1021 349 322 1429 931 P35556 0 Fibrillin-2 [Cleaved into: Placensin] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030023; GO:0030326; GO:0030501; GO:0031012; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 5609 XM_044321715.1 1021 349 322 1429 931 P35556 8.22e-180 Fibrillin-2 [Cleaved into: Placensin] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030023; GO:0030326; GO:0030501; GO:0031012; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 5610 XM_044321715.1 1021 349 322 1429 931 P35556 1.5e-178 Fibrillin-2 [Cleaved into: Placensin] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030023; GO:0030326; GO:0030501; GO:0031012; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 5611 XM_044321715.1 1021 349 322 1429 931 P35556 4.88e-162 Fibrillin-2 [Cleaved into: Placensin] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030023; GO:0030326; GO:0030501; GO:0031012; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 5612 XM_044321715.1 1021 349 322 1429 931 P35556 1.08e-112 Fibrillin-2 [Cleaved into: Placensin] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030023; GO:0030326; GO:0030501; GO:0031012; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 5613 XM_044321715.1 1021 349 322 1429 931 P35556 2.94e-83 Fibrillin-2 [Cleaved into: Placensin] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030023; GO:0030326; GO:0030501; GO:0031012; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 5614 XM_044309030.1 14 0 15 0 15 NA NA NA NA NA NA 5615 XR_003828239.2 6 22 1 2 13 NA NA NA NA NA NA 5616 XM_029342636.2 1330 714 362 538 91 Q58A42 3.33e-73 Protein DD3-3 Dictyostelium discoideum (Social amoeba) NA GO:0016020 5617 XM_029331051.2 152 66 35 106 67 NA NA NA NA NA NA 5618 XM_044312778.1 0 0 43 0 2 NA NA NA NA NA NA 5619 XM_044311003.1 567 218 230 358 223 NA NA NA NA NA NA 5620 XM_044318016.1 17 25 88 53 85 NA NA NA NA NA NA 5621 XR_006395617.1 421 42 182 331 70 Q2LE78 1.67e-38 BTB/POZ domain-containing protein 6 Xenopus laevis (African clawed frog) NA GO:0005737 5622 XM_044306913.1 20 0 0 0 0 NA NA NA NA NA NA 5623 XM_044326527.1 897 871 587 694 688 Q0P4V4 2.33e-84 Protein kintoun (Dynein assembly factor 2, axonemal) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) axonemal dynein complex assembly [GO:0070286]; cilium-dependent cell motility [GO:0060285] GO:0005737; GO:0060285; GO:0070286; GO:0120293 5624 XM_029347296.2 2367 3173 953 2041 1315 Q9I3S3 2.03e-142 Guanidinobutyrase (EC 3.5.3.7) Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) arginine catabolic process [GO:0006527]; putrescine biosynthetic process from arginine, using agmatinase [GO:0033389] GO:0006527; GO:0008783; GO:0033389; GO:0046872; GO:0047971 5625 XR_006392457.1 6 4 3 1 0 P0C0R5 6.84e-33 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) Rattus norvegicus (Rat) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006623; GO:0010506; GO:0015630; GO:0016236; GO:0016241; GO:0030242; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 5626 XR_006392457.1 6 4 3 1 0 P0C0R5 6.84e-33 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) Rattus norvegicus (Rat) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006623; GO:0010506; GO:0015630; GO:0016236; GO:0016241; GO:0030242; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 5627 XM_044311804.1 31 11 7 79 15 NA NA NA NA NA NA 5628 XM_029334796.2 261 164 94 239 98 Q5RGE6 4.31e-132 Heat shock 70 kDa protein 14 Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein refolding [GO:0042026]; vesicle-mediated transport [GO:0016192] GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0016192; GO:0016887; GO:0031072; GO:0034620; GO:0042026; GO:0044183; GO:0051082; GO:0051085; GO:0051787; GO:0140662 5629 XR_003825272.2 131 252 169 128 312 NA NA NA NA NA NA 5630 XM_029336798.2 1125 922 509 842 800 P43690 0 Developmentally-regulated GTP-binding protein 1 (DRG-1) (xDRG) (Translation factor GTPase DRG1) (TRAFAC GTPase DRG1) (EC 3.6.5.-) Xenopus laevis (African clawed frog) microtubule bundle formation [GO:0001578]; positive regulation of microtubule polymerization [GO:0031116] GO:0001578; GO:0003924; GO:0005525; GO:0005634; GO:0005737; GO:0008017; GO:0031116; GO:0046872 5631 XM_029343565.2 417 369 297 336 365 A5PJF6 8.4e-95 Inactive hydroxysteroid dehydrogenase-like protein 1 Bos taurus (Bovine) NA GO:0005739; GO:0045111 5632 XR_006397246.1 324 0 0 0 0 NA NA NA NA NA NA 5633 XM_029357996.2 314 5 12 181 182 NA NA NA NA NA NA 5634 XM_029352475.2 0 262 0 105 107 NA NA NA NA NA NA 5635 XM_044313547.1 276 65 218 204 330 NA NA NA NA NA NA 5636 XM_044311859.1 0 0 0 0 20 NA NA NA NA NA NA 5637 XM_029343885.2 2 43 17 8 44 A1L314 7.83e-153 Macrophage-expressed gene 1 protein (Macrophage gene 1 protein) (Mpg-1) (Perforin-2) (P-2) (Protein MPS1) Mus musculus (Mouse) antibacterial innate immune response [GO:0140367]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; disruption by host of symbiont membrane [GO:0052337] GO:0030659; GO:0031410; GO:0042742; GO:0045335; GO:0050829; GO:0050830; GO:0052337; GO:0140367 5638 XM_044310520.1 6 14 0 0 0 NA NA NA NA NA NA 5639 XR_003827036.2 9 6 2 0 0 NA NA NA NA NA NA 5640 XM_044321824.1 18 0 15 12 123 NA NA NA NA NA NA 5641 XM_029347276.2 0 0 9 0 14 A7SL20 4.09e-42 Ribosomal RNA processing protein 36 homolog Nematostella vectensis (Starlet sea anemone) cleavage involved in rRNA processing [GO:0000469]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462] GO:0000462; GO:0000469; GO:0005730; GO:0030686 5642 XM_029336542.2 745 483 537 605 742 Q9XT26 9.32e-118 Cyclin-T1 (CycT1) (Cyclin-T) Equus caballus (Horse) cell cycle [GO:0007049]; cell division [GO:0051301]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0005634; GO:0006357; GO:0007049; GO:0008024; GO:0016538; GO:0032786; GO:0032968; GO:0051301; GO:0061575; GO:0070691; GO:0097322; GO:0140693 5643 XM_044318177.1 394 34 29 74 71 F1LV46 2.1e-53 Indoleamine 2,3-dioxygenase 2 (IDO-2) (EC 1.13.11.-) (Indoleamine 2,3-dioxygenase-like protein 1) (Indoleamine-pyrrole 2,3-dioxygenase-like protein 1) Rattus norvegicus (Rat) 'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; immune system process [GO:0002376]; tryptophan catabolic process to kynurenine [GO:0019441] GO:0002376; GO:0004833; GO:0005737; GO:0019441; GO:0020037; GO:0033754; GO:0034354; GO:0046872 5644 XM_029345655.2 521 300 319 544 492 Q8ND61 2.52e-27 Uncharacterized protein C3orf20 Homo sapiens (Human) NA GO:0005737; GO:0016020 5645 XM_044323650.1 5 0 2 21 0 NA NA NA NA NA NA 5646 XM_044323073.1 97 59 68 127 101 Q96DM1 1.13e-71 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 5647 XM_029357278.2 3969 3601 2060 2786 3175 Q9R0K7 0 Plasma membrane calcium-transporting ATPase 2 (PMCA2) (EC 7.2.2.10) (Plasma membrane calcium ATPase isoform 2) (Plasma membrane calcium pump isoform 2) Mus musculus (Mouse) auditory receptor cell stereocilium organization [GO:0060088]; calcium ion transport [GO:0006816]; cell morphogenesis [GO:0000902]; cellular calcium ion homeostasis [GO:0006874]; cerebellar granule cell differentiation [GO:0021707]; cerebellar Purkinje cell differentiation [GO:0021702]; cerebellar Purkinje cell layer morphogenesis [GO:0021692]; cerebellum development [GO:0021549]; cGMP metabolic process [GO:0046068]; cochlea development [GO:0090102]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; establishment of localization in cell [GO:0051649]; inner ear development [GO:0048839]; inner ear morphogenesis [GO:0042472]; inner ear receptor cell differentiation [GO:0060113]; lactation [GO:0007595]; locomotion [GO:0040011]; locomotory behavior [GO:0007626]; neuromuscular process controlling balance [GO:0050885]; neuron cellular homeostasis [GO:0070050]; neuron differentiation [GO:0030182]; organelle organization [GO:0006996]; otolith mineralization [GO:0045299]; positive regulation of calcium ion transport [GO:0051928]; regulation of cell size [GO:0008361]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of synaptic plasticity [GO:0048167]; sensory perception of sound [GO:0007605]; serotonin metabolic process [GO:0042428]; synapse organization [GO:0050808] GO:0000902; GO:0005388; GO:0005509; GO:0005516; GO:0005524; GO:0005737; GO:0005783; GO:0005886; GO:0005929; GO:0006816; GO:0006874; GO:0006996; GO:0007595; GO:0007605; GO:0007626; GO:0008022; GO:0008361; GO:0016323; GO:0016324; GO:0016887; GO:0019829; GO:0021549; GO:0021692; GO:0021702; GO:0021707; GO:0030165; GO:0030182; GO:0030425; GO:0030899; GO:0032591; GO:0032809; GO:0035254; GO:0040011; GO:0042428; GO:0042472; GO:0042734; GO:0043005; GO:0043025; GO:0043231; GO:0045121; GO:0045211; GO:0045299; GO:0046068; GO:0048167; GO:0048787; GO:0048839; GO:0050808; GO:0050885; GO:0050910; GO:0051480; GO:0051649; GO:0051928; GO:0060088; GO:0060113; GO:0070050; GO:0090102; GO:0098684; GO:0098688; GO:0098839; GO:0098978; GO:0098982; GO:1905059 5648 XR_006394670.1 86 102 121 244 117 NA NA NA NA NA NA 5649 XM_029349278.2 1 0 78 106 187 A2RUV5 0 Probable ATP-dependent DNA helicase HFM1 (EC 3.6.4.12) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cellular component organization or biogenesis [GO:0071840]; meiotic cell cycle [GO:0051321] GO:0003676; GO:0004386; GO:0005524; GO:0016887; GO:0051321; GO:0071840 5650 XM_029340176.2 8 0 0 7 0 NA NA NA NA NA NA 5651 XM_029357408.2 23 28 60 54 84 Q9Z0U4 1.99e-61 Gamma-aminobutyric acid type B receptor subunit 1 (GABA-B receptor 1) (GABA-B-R1) (GABA-BR1) (GABABR1) (Gb1) Rattus norvegicus (Rat) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; chemical synaptic transmission [GO:0007268]; chemical synaptic transmission, postsynaptic [GO:0099565]; G protein-coupled receptor signaling pathway [GO:0007186]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of dopamine secretion [GO:0033602]; negative regulation of epinephrine secretion [GO:0032811]; negative regulation of gamma-aminobutyric acid secretion [GO:0014053]; negative regulation of synaptic transmission [GO:0050805]; neuron-glial cell signaling [GO:0150099]; osteoblast differentiation [GO:0001649]; positive regulation of glutamate secretion [GO:0014049]; positive regulation of growth hormone secretion [GO:0060124]; regulation of glutamate secretion [GO:0014048]; regulation of postsynaptic membrane potential [GO:0060078]; response to ethanol [GO:0045471]; response to nicotine [GO:0035094]; synaptic transmission, GABAergic [GO:0051932] GO:0001649; GO:0004888; GO:0004965; GO:0005615; GO:0005737; GO:0005789; GO:0005886; GO:0007186; GO:0007193; GO:0007194; GO:0007214; GO:0007268; GO:0008021; GO:0008285; GO:0014048; GO:0014049; GO:0014053; GO:0016020; GO:0030673; GO:0031966; GO:0032811; GO:0033602; GO:0035094; GO:0038037; GO:0038039; GO:0042734; GO:0043005; GO:0043025; GO:0043197; GO:0043198; GO:0043204; GO:0043231; GO:0045121; GO:0045211; GO:0045471; GO:0046982; GO:0050805; GO:0051932; GO:0060078; GO:0060124; GO:0097060; GO:0098685; GO:0098793; GO:0098978; GO:0098982; GO:0099565; GO:0099579; GO:0150047; GO:0150099; GO:1902710; GO:1902712; GO:1990430 5652 XM_029353630.2 9 4 9 0 0 NA NA NA NA NA NA 5653 XM_029338252.2 15629 13700 11844 17631 15442 Q28IJ3 4.73e-55 Prostamide/prostaglandin F synthase (Prostamide/PG F synthase) (Prostamide/PGF synthase) (EC 1.11.1.20) (Peroxiredoxin-like 2B) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) prostaglandin biosynthetic process [GO:0001516] GO:0001516; GO:0005829; GO:0016616 5654 XR_006394960.1 14 3 0 0 23 NA NA NA NA NA NA 5655 XM_044308174.1 568 499 335 515 524 NA NA NA NA NA NA 5656 XM_029331868.2 539 203 0 102 754 A2CEI6 0 Piwi-like protein 2 (EC 3.1.26.-) Danio rerio (Zebrafish) (Brachydanio rerio) DNA methylation involved in gamete generation [GO:0043046]; gamete generation [GO:0007276]; germ-line stem cell population maintenance [GO:0030718]; meiotic cell cycle [GO:0051321]; negative regulation of SMAD protein complex assembly [GO:0010991]; negative regulation of transposition [GO:0010529]; oogenesis [GO:0048477]; piRNA processing [GO:0034587]; positive regulation of gene expression [GO:0010628]; regulation of translation [GO:0006417]; rhythmic process [GO:0048511]; RNA 5'-end processing [GO:0000966]; RNA-mediated gene silencing [GO:0031047]; spermatogenesis [GO:0007283] GO:0000966; GO:0003723; GO:0004521; GO:0005634; GO:0005737; GO:0006417; GO:0007276; GO:0007283; GO:0010529; GO:0010628; GO:0010991; GO:0030718; GO:0031047; GO:0034584; GO:0034587; GO:0043046; GO:0043186; GO:0046872; GO:0048477; GO:0048511; GO:0051321; GO:0071546; GO:1990923 5657 XM_044328247.1 0 9 0 0 0 Q8C261 6.08e-41 Sodium/potassium/calcium exchanger 5 (Na(+)/K(+)/Ca(2+)-exchange protein 5) (Solute carrier family 24 member 5) Mus musculus (Mouse) calcium ion import [GO:0070509]; calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; ion transmembrane transport [GO:0034220]; melanin biosynthetic process [GO:0042438]; melanocyte differentiation [GO:0030318]; negative regulation of melanin biosynthetic process [GO:0048022]; response to stimulus [GO:0050896] GO:0005262; GO:0005802; GO:0006874; GO:0008273; GO:0015085; GO:0015293; GO:0016020; GO:0030318; GO:0034220; GO:0042438; GO:0042470; GO:0048022; GO:0050896; GO:0070509; GO:0070588 5658 XM_044308143.1 157 19 123 55 611 NA NA NA NA NA NA 5659 XM_029348993.2 390 226 0 0 180 P25931 9.93e-24 RYamide receptor (Neuropeptide Y-like receptor) (NPY-R) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218] GO:0001653; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0016020 5660 XM_044318247.1 1 0 3 0 14 NA NA NA NA NA NA 5661 XM_044319943.1 357 324 336 394 301 O34313 9.01e-36 Trifunctional nucleotide phosphoesterase protein YfkN [Includes: 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase (EC 3.1.3.6) (EC 3.1.4.16); 5'-nucleotidase (EC 3.1.3.5)] Bacillus subtilis (strain 168) nucleotide catabolic process [GO:0009166] GO:0000166; GO:0005576; GO:0008254; GO:0008663; GO:0009166; GO:0030288; GO:0046872; GO:0106411 5662 XM_029357600.2 3908 4020 1781 2744 2403 NA NA NA NA NA NA 5663 XM_044313930.1 0 0 3 0 8 NA NA NA NA NA NA 5664 XM_029346960.2 0 8 0 5 0 Q502K3 3.98e-23 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (PP6-ARS-C) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C) Danio rerio (Zebrafish) (Brachydanio rerio) NA NA 5665 XR_006394071.1 2 4 72 21 360 Q09575 9.81e-31 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 5666 XM_044321029.1 323 106 81 107 134 Q28C69 4.59e-76 Enolase-phosphatase E1 (EC 3.1.3.77) (2,3-diketo-5-methylthio-1-phosphopentane phosphatase) (MASA homolog) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284] GO:0000287; GO:0005634; GO:0005737; GO:0019284; GO:0019509; GO:0043715; GO:0043716; GO:0043874 5667 XM_029338141.2 4468 3114 990 2514 1742 O60568 0 Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 [Includes: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 (EC 1.14.11.4) (Lysyl hydroxylase 3) (LH3); Procollagen glycosyltransferase (EC 2.4.1.50) (EC 2.4.1.66) (Galactosylhydroxylysine-glucosyltransferase) (Procollagen galactosyltransferase) (Procollagen glucosyltransferase)] Homo sapiens (Human) basement membrane assembly [GO:0070831]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; endothelial cell morphogenesis [GO:0001886]; epidermis morphogenesis [GO:0048730]; hydroxylysine biosynthetic process [GO:0046947]; in utero embryonic development [GO:0001701]; lung morphogenesis [GO:0060425]; neural tube development [GO:0021915]; peptidyl-lysine hydroxylation [GO:0017185]; protein localization [GO:0008104]; protein O-linked glycosylation [GO:0006493]; sequestering of metal ion [GO:0051238]; vasodilation [GO:0042311] GO:0001701; GO:0001886; GO:0005506; GO:0005615; GO:0005783; GO:0005788; GO:0005789; GO:0005791; GO:0005794; GO:0005802; GO:0006493; GO:0008104; GO:0008475; GO:0017185; GO:0021915; GO:0030199; GO:0031418; GO:0032963; GO:0033823; GO:0036094; GO:0042311; GO:0046872; GO:0046947; GO:0048730; GO:0050211; GO:0051238; GO:0060425; GO:0062023; GO:0070062; GO:0070831 5668 XM_029326525.2 0 0 0 0 7 NA NA NA NA NA NA 5669 XM_044312082.1 0 27 5 28 0 NA NA NA NA NA NA 5670 XM_029333789.1 976 936 831 954 707 Q17427 3.36e-49 Glucosamine 6-phosphate N-acetyltransferase (EC 2.3.1.4) (Phosphoglucosamine acetylase) (Phosphoglucosamine transacetylase) Caenorhabditis elegans UDP-N-acetylglucosamine biosynthetic process [GO:0006048] GO:0004343; GO:0005783; GO:0005793; GO:0005794; GO:0006048; GO:0008080; GO:0048029 5671 XM_029346781.2 44 20 7 42 53 NA NA NA NA NA NA 5672 XM_029330256.2 437 358 142 157 265 NA NA NA NA NA NA 5673 XR_006397292.1 27 0 2 47 11 NA NA NA NA NA NA 5674 XM_029323423.2 0 10 11 1 4 Q99315 1.21e-64 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 5675 XM_029348846.2 1655 1235 1178 1460 1698 A0PJN4 5.44e-62 Ubiquitin-conjugating enzyme E2Q-like protein 1 (EC 2.3.2.23) (E2Q-like ubiquitin-conjugating enzyme 1) Mus musculus (Mouse) protein polyubiquitination [GO:0000209] GO:0000209; GO:0005524; GO:0005634; GO:0005654; GO:0005886; GO:0061631 5676 XM_044322703.1 0 0 0 21 0 NA NA NA NA NA NA 5677 XM_044316182.1 145 135 86 226 232 Q13395 6.67e-56 Probable methyltransferase TARBP1 (EC 2.1.1.-) (TAR RNA-binding protein 1) (TAR RNA-binding protein of 185 kDa) (TRP-185) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357]; tRNA methylation [GO:0030488] GO:0003723; GO:0005634; GO:0006357; GO:0016423; GO:0030488 5678 XM_044316182.1 145 135 86 226 232 Q13395 6.67e-56 Probable methyltransferase TARBP1 (EC 2.1.1.-) (TAR RNA-binding protein 1) (TAR RNA-binding protein of 185 kDa) (TRP-185) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357]; tRNA methylation [GO:0030488] GO:0003723; GO:0005634; GO:0006357; GO:0016423; GO:0030488 5679 XM_044318863.1 87 178 385 0 241 NA NA NA NA NA NA 5680 XM_029333366.2 1854 1530 839 1118 792 P31335 0 Bifunctional purine biosynthesis protein ATIC (AICAR transformylase/inosine monophosphate cyclohydrolase) (ATIC) [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase) (AICAR formyltransferase) (AICAR transformylase); Inosine 5'-monophosphate cyclohydrolase (IMP cyclohydrolase) (EC 3.5.4.10) (IMP synthase) (Inosinicase)] Gallus gallus (Chicken) 'de novo' IMP biosynthetic process [GO:0006189] GO:0003937; GO:0004643; GO:0005829; GO:0006189; GO:0042803 5681 XM_044317651.1 95 3 0 5 28 NA NA NA NA NA NA 5682 XM_044322202.1 579 667 431 191 368 Q62074 0 Protein kinase C iota type (EC 2.7.11.13) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (nPKC-iota) Mus musculus (Mouse) actin filament organization [GO:0007015]; cell migration [GO:0016477]; cell-cell junction organization [GO:0045216]; cellular response to insulin stimulus [GO:0032869]; establishment of apical/basal cell polarity [GO:0035089]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; eye photoreceptor cell development [GO:0042462]; Golgi vesicle budding [GO:0048194]; intracellular signal transduction [GO:0035556]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron apoptotic process [GO:0043524]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of glucose import [GO:0046326]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; response to interleukin-1 [GO:0070555]; response to peptide hormone [GO:0043434] GO:0000139; GO:0004672; GO:0004674; GO:0004697; GO:0004698; GO:0005524; GO:0005543; GO:0005634; GO:0005737; GO:0005768; GO:0005829; GO:0005886; GO:0005903; GO:0005923; GO:0006468; GO:0007015; GO:0008104; GO:0010976; GO:0015630; GO:0016324; GO:0016477; GO:0018105; GO:0031252; GO:0032869; GO:0034351; GO:0035089; GO:0035556; GO:0042462; GO:0043220; GO:0043434; GO:0043524; GO:0045171; GO:0045177; GO:0045197; GO:0045216; GO:0046326; GO:0046872; GO:0048194; GO:0051092; GO:0060252; GO:0070555; GO:0098685; GO:0098978; GO:0099072; GO:0106310; GO:0120157; GO:1903078; GO:2000353 5683 XR_003824566.2 7 19 7 32 14 NA NA NA NA NA NA 5684 XM_029349085.2 447 388 422 435 431 O14059 2.25e-68 Probable histidinol-phosphatase (HolPase) (EC 3.1.3.15) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) histidine biosynthetic process [GO:0000105] GO:0000105; GO:0004401; GO:0005634; GO:0005829 5685 XM_044326687.1 316 283 116 143 183 NA NA NA NA NA NA 5686 XM_044325390.1 9 0 40 1 28 P07911 2.72e-32 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Homo sapiens (Human) antibacterial innate immune response [GO:0140367]; apoptotic signaling pathway [GO:0097190]; autophagy [GO:0006914]; cellular calcium ion homeostasis [GO:0006874]; cellular chloride ion homeostasis [GO:0030644]; cellular defense response [GO:0006968]; cellular phosphate ion homeostasis [GO:0030643]; cellular response to unfolded protein [GO:0034620]; cellular sodium ion homeostasis [GO:0006883]; chaperone-mediated protein folding [GO:0061077]; citric acid secretion [GO:0046720]; collecting duct development [GO:0072044]; connective tissue replacement [GO:0097709]; creatinine homeostasis [GO:0097273]; defense response to Gram-negative bacterium [GO:0050829]; endoplasmic reticulum organization [GO:0007029]; glomerular filtration [GO:0003094]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; juxtaglomerular apparatus development [GO:0072051]; leukocyte cell-cell adhesion [GO:0007159]; lipid metabolic process [GO:0006629]; metanephric ascending thin limb development [GO:0072218]; metanephric distal convoluted tubule development [GO:0072221]; metanephric thick ascending limb development [GO:0072233]; micturition [GO:0060073]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell population proliferation [GO:0008285]; neutrophil migration [GO:1990266]; organ or tissue specific immune response [GO:0002251]; peptidyl-threonine phosphorylation [GO:0018107]; potassium ion homeostasis [GO:0055075]; protein localization to vacuole [GO:0072665]; protein transport into plasma membrane raft [GO:0044861]; regulation of blood pressure [GO:0008217]; regulation of protein transport [GO:0051223]; regulation of urine volume [GO:0035809]; renal sodium ion absorption [GO:0070294]; renal urate salt excretion [GO:0097744]; renal water homeostasis [GO:0003091]; response to lipopolysaccharide [GO:0032496]; response to water deprivation [GO:0009414]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; ubiquitin-dependent ERAD pathway [GO:0030433]; urate transport [GO:0015747]; urea transmembrane transport [GO:0071918] GO:0000922; GO:0002251; GO:0003091; GO:0003094; GO:0005201; GO:0005509; GO:0005615; GO:0005783; GO:0005796; GO:0005929; GO:0006629; GO:0006874; GO:0006883; GO:0006914; GO:0006954; GO:0006968; GO:0007029; GO:0007157; GO:0007159; GO:0008217; GO:0008285; GO:0008380; GO:0009410; GO:0009414; GO:0009986; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0018107; GO:0019864; GO:0019898; GO:0030433; GO:0030643; GO:0030644; GO:0032496; GO:0033209; GO:0033555; GO:0034620; GO:0035809; GO:0044861; GO:0046720; GO:0050829; GO:0051223; GO:0055075; GO:0060073; GO:0060170; GO:0061077; GO:0070062; GO:0070294; GO:0071918; GO:0072044; GO:0072051; GO:0072218; GO:0072221; GO:0072233; GO:0072665; GO:0097190; GO:0097273; GO:0097709; GO:0097744; GO:0140367; GO:1990266 5687 XM_044311860.1 79 15 20 29 63 Q80XJ3 4.58e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 5688 XM_044311860.1 79 15 20 29 63 Q80XJ3 2.07e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 5689 XM_044311860.1 79 15 20 29 63 Q80XJ3 1.2e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 5690 XM_044311860.1 79 15 20 29 63 Q80XJ3 1.61e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 5691 XM_044311860.1 79 15 20 29 63 Q80XJ3 6.15e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 5692 XM_044311860.1 79 15 20 29 63 Q80XJ3 1.52e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 5693 XM_044311860.1 79 15 20 29 63 Q80XJ3 2.76e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 5694 XM_044311860.1 79 15 20 29 63 Q80XJ3 9.83e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 5695 XM_029341044.2 225 231 203 162 332 NA NA NA NA NA NA 5696 XM_044308676.1 245 737 0 0 0 Q13591 7.07e-29 Semaphorin-5A (Semaphorin-F) (Sema F) Homo sapiens (Human) axon extension [GO:0048675]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell-cell signaling [GO:0007267]; diencephalon development [GO:0021536]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of cell adhesion [GO:0007162]; negative regulation of endothelial cell apoptotic process [GO:2000352]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; positive chemotaxis [GO:0050918]; positive regulation of actin filament depolymerization [GO:0030836]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein kinase B signaling [GO:0051897]; semaphorin-plexin signaling pathway [GO:0071526]; signal clustering [GO:1990256] GO:0001755; GO:0001938; GO:0002043; GO:0005886; GO:0007155; GO:0007162; GO:0007267; GO:0007399; GO:0007411; GO:0007413; GO:0016020; GO:0021536; GO:0030215; GO:0030335; GO:0030836; GO:0035373; GO:0043395; GO:0045499; GO:0045545; GO:0045766; GO:0048675; GO:0048842; GO:0048843; GO:0050918; GO:0051897; GO:0060326; GO:0070062; GO:0071526; GO:0090263; GO:1990256; GO:2000352; GO:2001028 5697 XM_029351565.2 1423 1970 995 1700 1443 Q7SYS9 9.86e-25 Histamine N-methyltransferase B (HMT B) (EC 2.1.1.8) Xenopus laevis (African clawed frog) histamine catabolic process [GO:0001695]; methylation [GO:0032259] GO:0001695; GO:0005737; GO:0032259; GO:0046539 5698 XM_044306819.1 0 0 0 0 12 NA NA NA NA NA NA 5699 XM_044323469.1 58 2 36 27 0 B8UU78 1.49e-131 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 5700 XM_044316512.1 0 0 22 31 4 NA NA NA NA NA NA 5701 XM_029342556.2 615 403 319 397 904 Q5ZKH8 3.47e-54 Protein odr-4 homolog Gallus gallus (Chicken) protein localization [GO:0008104] GO:0008104; GO:0016020 5702 XM_029328984.2 34 49 14 44 20 NA NA NA NA NA NA 5703 XM_044307895.1 54 36 56 47 78 NA NA NA NA NA NA 5704 XM_044320531.1 86 22 80 67 93 Q7RTR2 5.37e-59 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 5705 XM_044320531.1 86 22 80 67 93 Q7RTR2 2.53e-55 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 5706 XM_044320531.1 86 22 80 67 93 Q7RTR2 1.16e-54 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 5707 XM_044320531.1 86 22 80 67 93 Q7RTR2 2.08e-53 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 5708 XM_044320531.1 86 22 80 67 93 Q7RTR2 1.17e-43 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 5709 XM_044320531.1 86 22 80 67 93 Q7RTR2 7.92e-43 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 5710 XR_003825888.2 21 6 7 24 12 NA NA NA NA NA NA 5711 XM_029357231.2 121 0 0 0 43 Q9ES08 2.69e-24 Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3) (Two pore potassium channel KT3.2) (Two pore K(+) channel KT3.2) Rattus norvegicus (Rat) potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of ion transmembrane transport [GO:0034765]; stabilization of membrane potential [GO:0030322] GO:0005249; GO:0005267; GO:0005886; GO:0006813; GO:0008021; GO:0015271; GO:0022841; GO:0030322; GO:0034765; GO:0071805; GO:1990573 5712 XM_029348485.2 972 416 441 809 631 Q90744 1.07e-137 Alpha-N-acetylgalactosaminidase (EC 3.2.1.49) (Alpha-galactosidase B) Gallus gallus (Chicken) glycoside catabolic process [GO:0016139]; lipid metabolic process [GO:0006629]; oligosaccharide metabolic process [GO:0009311] GO:0004557; GO:0005737; GO:0005764; GO:0006629; GO:0008456; GO:0009311; GO:0016139 5713 XM_044311030.1 1 0 20 11 44 NA NA NA NA NA NA 5714 XM_044317719.1 55 15 10 26 5 Q503V3 2.93e-32 SREBP regulating gene protein Danio rerio (Zebrafish) (Brachydanio rerio) positive regulation of SREBP signaling pathway [GO:2000640] GO:0000139; GO:2000640 5715 XR_006391852.1 1 0 0 0 6 NA NA NA NA NA NA 5716 XM_029333357.2 0 9 2 0 7 Q09575 8.01e-21 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 5717 XM_029337148.2 767 249 344 378 631 Q2TAW0 1.04e-163 Condensin-2 complex subunit G2 (Chromosome-associated protein G2) (Non-SMC condensin II complex subunit G2) (XCAP-G2) Xenopus laevis (African clawed frog) cell cycle [GO:0007049]; cell division [GO:0051301]; chromosome condensation [GO:0030261] GO:0005634; GO:0007049; GO:0030261; GO:0051301 5718 XM_029345165.2 2220 2286 1373 2883 1892 Q96PQ7 0 Kelch-like protein 5 Homo sapiens (Human) NA GO:0003779; GO:0005737; GO:0005829; GO:0005856 5719 XR_006392551.1 11 32 4 47 39 NA NA NA NA NA NA 5720 XR_006395586.1 0 0 0 25 57 Q20191 2.48e-51 Zinc metalloproteinase nas-13 (EC 3.4.24.-) (Nematode astacin 13) Caenorhabditis elegans proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0006508; GO:0008270 5721 XM_029356728.2 2685 2476 2157 2677 3097 Q9UPY8 3.04e-94 Microtubule-associated protein RP/EB family member 3 (EB1 protein family member 3) (EBF3) (End-binding protein 3) (EB3) (RP3) Homo sapiens (Human) cell division [GO:0051301]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of microtubule plus-end binding [GO:1903033]; positive regulation of protein kinase activity [GO:0045860]; protein localization [GO:0008104]; protein localization to microtubule [GO:0035372]; regulation of microtubule polymerization [GO:0031113]; regulation of microtubule polymerization or depolymerization [GO:0031110]; spindle assembly [GO:0051225] GO:0005737; GO:0005815; GO:0008017; GO:0008022; GO:0008104; GO:0015630; GO:0019901; GO:0030496; GO:0031110; GO:0031113; GO:0035371; GO:0035372; GO:0042802; GO:0045737; GO:0045860; GO:0045893; GO:0048471; GO:0051010; GO:0051225; GO:0051233; GO:0051301; GO:1903033; GO:1905721 5722 XM_029332409.2 458 614 230 531 330 Q17QH8 8.67e-111 Epimerase family protein SDR39U1 (EC 1.1.1.-) (Short-chain dehydrogenase/reductase family 39U member 1) Bos taurus (Bovine) NA GO:0016491 5723 XM_044318953.1 344 0 177 510 190 P07607 6.57e-164 Thymidylate synthase (TS) (TSase) (EC 2.1.1.45) Mus musculus (Mouse) aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; methylation [GO:0032259]; negative regulation of translation [GO:0017148]; regulation of translation [GO:0006417]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to toxic substance [GO:0009636]; response to vitamin A [GO:0033189]; response to xenobiotic stimulus [GO:0009410]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860] GO:0000900; GO:0003729; GO:0004799; GO:0005542; GO:0005634; GO:0005730; GO:0005737; GO:0005739; GO:0005743; GO:0005759; GO:0005829; GO:0006231; GO:0006235; GO:0006417; GO:0007568; GO:0007623; GO:0009410; GO:0009636; GO:0017148; GO:0019860; GO:0032259; GO:0032570; GO:0033189; GO:0034097; GO:0035999; GO:0042803; GO:0045471; GO:0046683; GO:0048589; GO:0051216; GO:0051384; GO:0051593; GO:0060574; GO:0097421; GO:1901363; GO:1990825 5724 XM_029349377.2 2444 2056 1247 1686 1319 Q07130 0 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) (UDP-glucose pyrophosphorylase) (UDPGP) (UGPase) Bos taurus (Bovine) glycogen biosynthetic process [GO:0005978]; glycogen metabolic process [GO:0005977]; UDP-glucose metabolic process [GO:0006011] GO:0003983; GO:0005737; GO:0005977; GO:0005978; GO:0006011; GO:0046872 5725 XM_029351011.2 0 0 0 38 1 Q5R9E1 9.12e-129 Hydroxymethylglutaryl-CoA lyase, mitochondrial (HL) (HMG-CoA lyase) (EC 4.1.3.4) (3-hydroxy-3-methylglutarate-CoA lyase) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) ketone body biosynthetic process [GO:0046951] GO:0004419; GO:0005759; GO:0005777; GO:0046872; GO:0046951 5726 XM_044311319.1 39 9 40 25 7 Q96G03 3.93e-69 Phosphopentomutase (EC 5.4.2.7) (Glucose phosphomutase 2) (Phosphodeoxyribomutase) (Phosphoglucomutase-2) (EC 5.4.2.2) Homo sapiens (Human) glucose metabolic process [GO:0006006]; glycogen catabolic process [GO:0005980]; purine ribonucleoside salvage [GO:0006166] GO:0000287; GO:0004614; GO:0005576; GO:0005829; GO:0005980; GO:0006006; GO:0006166; GO:0008973; GO:0034774; GO:0070062; GO:1904813 5727 XR_006397312.1 605 1766 1323 975 1320 NA NA NA NA NA NA 5728 XM_029346763.2 16 0 0 18 98 NA NA NA NA NA NA 5729 XM_029351800.2 226 380 236 217 125 NA NA NA NA NA NA 5730 XR_006396796.1 18 0 0 0 0 NA NA NA NA NA NA 5731 XM_029327486.2 254 876 1476 1381 24 NA NA NA NA NA NA 5732 XM_044319909.1 1 0 6 1 7 NA NA NA NA NA NA 5733 XM_044323370.1 41 14 11 96 13 NA NA NA NA NA NA 5734 XM_044318245.1 64 198 171 230 0 Q9HAR2 9.93e-67 Adhesion G protein-coupled receptor L3 (Calcium-independent alpha-latrotoxin receptor 3) (CIRL-3) (Latrophilin-3) (Lectomedin-3) Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; brain development [GO:0007420]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; G protein-coupled receptor signaling pathway [GO:0007186]; neuron migration [GO:0001764]; synapse assembly [GO:0007416] GO:0001764; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007166; GO:0007186; GO:0007189; GO:0007416; GO:0007420; GO:0016020; GO:0030246; GO:0030424; GO:0098742; GO:0098978 5735 XR_006397780.1 719 1584 657 1565 753 NA NA NA NA NA NA 5736 XM_029358338.2 168 119 110 98 127 P35789 1.85e-42 Zinc finger protein 93 (Zinc finger protein 505) (Zinc finger protein HTF34) Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transposon integration [GO:0070895]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0003700; GO:0005634; GO:0006357; GO:0008270; GO:0045892; GO:0070895 5737 XM_029358338.2 168 119 110 98 127 P35789 1.45e-34 Zinc finger protein 93 (Zinc finger protein 505) (Zinc finger protein HTF34) Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transposon integration [GO:0070895]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0003700; GO:0005634; GO:0006357; GO:0008270; GO:0045892; GO:0070895 5738 XM_029358338.2 168 119 110 98 127 P35789 1.44e-33 Zinc finger protein 93 (Zinc finger protein 505) (Zinc finger protein HTF34) Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transposon integration [GO:0070895]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0003700; GO:0005634; GO:0006357; GO:0008270; GO:0045892; GO:0070895 5739 XM_029358338.2 168 119 110 98 127 P35789 6.71e-32 Zinc finger protein 93 (Zinc finger protein 505) (Zinc finger protein HTF34) Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transposon integration [GO:0070895]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0003700; GO:0005634; GO:0006357; GO:0008270; GO:0045892; GO:0070895 5740 XM_029358338.2 168 119 110 98 127 P35789 1.45e-30 Zinc finger protein 93 (Zinc finger protein 505) (Zinc finger protein HTF34) Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transposon integration [GO:0070895]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0003700; GO:0005634; GO:0006357; GO:0008270; GO:0045892; GO:0070895 5741 XR_003827021.2 0 11 0 0 0 NA NA NA NA NA NA 5742 XM_044314435.1 160 512 48 334 519 NA NA NA NA NA NA 5743 XM_029348598.2 0 0 0 102 498 Q5RE70 0 Integrator complex subunit 3 (Int3) (SOSS complex subunit A) (Sensor of single-strand DNA complex subunit A) (SOSS-A) (Sensor of ssDNA subunit A) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; mitotic G2/M transition checkpoint [GO:0044818]; response to ionizing radiation [GO:0010212] GO:0005634; GO:0005737; GO:0006281; GO:0006974; GO:0010212; GO:0044818; GO:0070876 5744 XM_044313223.1 413 263 217 348 435 Q90511 1.48e-141 Translation initiation factor eIF-2B subunit beta (S20I15) (eIF-2B GDP-GTP exchange factor subunit beta) Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) central nervous system development [GO:0007417]; myelination [GO:0042552]; oligodendrocyte development [GO:0014003]; T cell receptor signaling pathway [GO:0050852]; translational initiation [GO:0006413] GO:0003743; GO:0005524; GO:0005525; GO:0005737; GO:0005851; GO:0006413; GO:0007417; GO:0014003; GO:0042552; GO:0050852 5745 XM_029355546.2 184 156 4 0 182 A4IIW7 3.16e-140 Cyclin-dependent kinase 14 (EC 2.7.11.22) (Cell division protein kinase 14) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell division [GO:0051301]; G2/M transition of mitotic cell cycle [GO:0000086]; protein phosphorylation [GO:0006468]; regulation of canonical Wnt signaling pathway [GO:0060828]; Wnt signaling pathway [GO:0016055] GO:0000086; GO:0000308; GO:0004693; GO:0005524; GO:0005886; GO:0006468; GO:0016055; GO:0051301; GO:0060828; GO:0106310 5746 XM_044325652.1 19 13 19 39 44 NA NA NA NA NA NA 5747 XM_044309032.1 0 0 25 9 34 NA NA NA NA NA NA 5748 XR_006396046.1 0 7 0 20 0 NA NA NA NA NA NA 5749 XM_044317240.1 9 0 0 5 0 NA NA NA NA NA NA 5750 XM_029356234.2 8 0 0 0 0 NA NA NA NA NA NA 5751 XM_029346081.2 821 564 740 1100 1189 Q94515 1.3e-156 Sphingolipid delta(4)-desaturase DES1 (EC 1.14.19.17) (Degenerative spermatocyte homolog 1) (DES-1) (Dihydroceramide desaturase-1) Drosophila melanogaster (Fruit fly) ceramide biosynthetic process [GO:0046513]; negative regulation of lipophagy [GO:1904503]; spermatogenesis [GO:0007283]; spindle assembly involved in male meiosis [GO:0007053] GO:0005739; GO:0005770; GO:0005783; GO:0005789; GO:0005886; GO:0007053; GO:0007283; GO:0016006; GO:0042284; GO:0046513; GO:0070938; GO:1904503 5752 XM_044316795.1 0 0 0 0 6 NA NA NA NA NA NA 5753 XM_044316556.1 0 0 0 0 25 NA NA NA NA NA NA 5754 XM_029343850.2 174 97 61 123 79 NA NA NA NA NA NA 5755 XM_044313872.1 133 141 214 118 728 Q9DBE9 8.85e-106 pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3 (EC 2.1.1.-) (Protein ftsJ homolog 3) (Putative rRNA methyltransferase 3) Mus musculus (Mouse) enzyme-directed rRNA 2'-O-methylation [GO:0000453]; maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000466]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; RNA methylation [GO:0001510]; rRNA methylation [GO:0031167] GO:0000453; GO:0000463; GO:0000466; GO:0001510; GO:0005654; GO:0005694; GO:0005730; GO:0008173; GO:0008650; GO:0016435; GO:0030687; GO:0030688; GO:0031167; GO:0062105 5756 XM_044313872.1 133 141 214 118 728 Q9DBE9 1.76e-57 pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3 (EC 2.1.1.-) (Protein ftsJ homolog 3) (Putative rRNA methyltransferase 3) Mus musculus (Mouse) enzyme-directed rRNA 2'-O-methylation [GO:0000453]; maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000466]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; RNA methylation [GO:0001510]; rRNA methylation [GO:0031167] GO:0000453; GO:0000463; GO:0000466; GO:0001510; GO:0005654; GO:0005694; GO:0005730; GO:0008173; GO:0008650; GO:0016435; GO:0030687; GO:0030688; GO:0031167; GO:0062105 5757 XM_044313872.1 133 141 214 118 728 Q9DBE9 1.42e-41 pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3 (EC 2.1.1.-) (Protein ftsJ homolog 3) (Putative rRNA methyltransferase 3) Mus musculus (Mouse) enzyme-directed rRNA 2'-O-methylation [GO:0000453]; maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000466]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; RNA methylation [GO:0001510]; rRNA methylation [GO:0031167] GO:0000453; GO:0000463; GO:0000466; GO:0001510; GO:0005654; GO:0005694; GO:0005730; GO:0008173; GO:0008650; GO:0016435; GO:0030687; GO:0030688; GO:0031167; GO:0062105 5758 XM_044314619.1 25 31 5 11 50 P51955 2.08e-128 Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis A-related kinase 2) (NimA-related protein kinase 2) (NimA-like protein kinase 1) Homo sapiens (Human) blastocyst development [GO:0001824]; cell division [GO:0051301]; centrosome separation [GO:0051299]; chromosome segregation [GO:0007059]; meiotic cell cycle [GO:0051321]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly [GO:0090307]; negative regulation of centriole-centriole cohesion [GO:1903126]; negative regulation of DNA binding [GO:0043392]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of mitotic centrosome separation [GO:0046602]; regulation of mitotic nuclear division [GO:0007088]; spindle assembly [GO:0051225] GO:0000070; GO:0000278; GO:0000776; GO:0000794; GO:0000922; GO:0001824; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005813; GO:0005829; GO:0005874; GO:0006468; GO:0007059; GO:0007088; GO:0019903; GO:0030496; GO:0032212; GO:0032991; GO:0043392; GO:0046602; GO:0046777; GO:0046872; GO:0051225; GO:0051299; GO:0051301; GO:0051321; GO:0051973; GO:0051988; GO:0090307; GO:0106310; GO:1903126; GO:1904355 5759 XR_006396019.1 41 60 75 25 258 NA NA NA NA NA NA 5760 XM_044319781.1 372 119 103 1178 517 Q9P2E3 0 NFX1-type zinc finger-containing protein 1 Homo sapiens (Human) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 5761 XM_044319781.1 372 119 103 1178 517 Q9P2E3 5.36e-68 NFX1-type zinc finger-containing protein 1 Homo sapiens (Human) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 5762 XM_029344884.2 467 440 256 325 337 NA NA NA NA NA NA 5763 XM_044309837.1 1116 1656 2686 3892 2853 Q29RU2 2.19e-35 Oncoprotein-induced transcript 3 protein Bos taurus (Bovine) NA GO:0005509; GO:0005635 5764 XM_044322877.1 697 552 473 655 541 F6XBL2 0 26S proteasome non-ATPase regulatory subunit 11 (26S proteasome regulatory subunit RPN6) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) proteasome assembly [GO:0043248]; stem cell differentiation [GO:0048863]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0005634; GO:0005829; GO:0006511; GO:0022624; GO:0043248; GO:0048863 5765 XM_044327207.1 6 26 6 14 6 NA NA NA NA NA NA 5766 XM_029349113.2 935 771 638 808 911 O60941 3.29e-156 Dystrobrevin beta (DTN-B) (Beta-dystrobrevin) Homo sapiens (Human) neuron differentiation [GO:0030182]; synaptic signaling [GO:0099536] GO:0005634; GO:0005737; GO:0005886; GO:0008270; GO:0009925; GO:0014069; GO:0030182; GO:0030425; GO:0045202; GO:0060077; GO:0099536 5767 XM_044329311.1 2050 1727 1204 1606 1148 Q9CXR1 3.55e-80 Dehydrogenase/reductase SDR family member 7 (EC 1.1.1.-) (Retinal short-chain dehydrogenase/reductase 4) (retSDR4) (Short chain dehydrogenase/reductase family 34C member 1) (Protein SDR34C1) Mus musculus (Mouse) NA GO:0004090; GO:0005789; GO:0016616; GO:0052650 5768 XM_044324715.1 0 164 127 468 5385 NA NA NA NA NA NA 5769 XM_044324323.1 183 413 256 182 239 NA NA NA NA NA NA 5770 XM_044320265.1 116 0 13 0 0 NA NA NA NA NA NA 5771 XM_044326293.1 664 139 151 206 271 Q5VU97 2.26e-151 VWFA and cache domain-containing protein 1 (Cache domain-containing protein 1) Homo sapiens (Human) NA GO:0005245; GO:0005891 5772 XM_029346659.2 405 477 269 465 736 NA NA NA NA NA NA 5773 XM_029331909.2 65 0 55 188 256 Q9BQS2 4.24e-55 Synaptotagmin-15 (Chr10Syt) (Synaptotagmin XV) (SytXV) Homo sapiens (Human) calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; vesicle-mediated transport [GO:0016192] GO:0000149; GO:0001786; GO:0005509; GO:0005544; GO:0005886; GO:0014059; GO:0016192; GO:0017156; GO:0017158; GO:0030276; GO:0070382; GO:0071277 5774 XM_029337812.2 602 355 250 411 560 Q9Y5B6 5.59e-147 PAX3- and PAX7-binding protein 1 (GC-rich sequence DNA-binding factor 1) Homo sapiens (Human) mRNA splicing, via spliceosome [GO:0000398]; muscle organ development [GO:0007517]; positive regulation of histone methylation [GO:0031062]; positive regulation of myoblast proliferation [GO:2000288]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of skeletal muscle satellite cell proliferation [GO:0014842]; transcription by RNA polymerase II [GO:0006366] GO:0000398; GO:0003677; GO:0005634; GO:0005829; GO:0006366; GO:0007517; GO:0014842; GO:0031062; GO:0045944; GO:1990226; GO:2000288 5775 XM_029326855.2 541 315 129 291 389 NA NA NA NA NA NA 5776 XM_044309654.1 87 16 39 13 65 NA NA NA NA NA NA 5777 XM_029349952.2 106 587 221 1453 873 O42097 4.12e-71 Hepatocyte nuclear factor 3-beta (HNF-3-beta) (HNF-3B) (Forkhead box protein A2) (Me-HNF3B) Oryzias latipes (Japanese rice fish) (Japanese killifish) anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; regulation of transcription by RNA polymerase II [GO:0006357]; system development [GO:0048731] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0009653; GO:0019904; GO:0030154; GO:0048731 5778 XM_044326361.1 14 0 1 58 13 NA NA NA NA NA NA 5779 XM_029341993.2 1427 1167 993 1032 1300 E2QTD3 4.86e-55 Tudor domain-containing protein 5 Canis lupus familiaris (Dog) (Canis familiaris) DNA methylation involved in gamete generation [GO:0043046]; P granule organization [GO:0030719]; piRNA processing [GO:0034587]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283] GO:0007283; GO:0007286; GO:0030719; GO:0033391; GO:0034587; GO:0043046; GO:0043186; GO:0071546 5780 XM_029340426.2 0 15 9 6 21 NA NA NA NA NA NA 5781 XM_029338951.2 1931 2591 2703 5017 2692 NA NA NA NA NA NA 5782 XM_044328369.1 16 1 17 3 129 NA NA NA NA NA NA 5783 XM_044327318.1 0 0 1 14 86 B3EWZ5 3.77e-22 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 5784 XM_029339744.2 20 0 0 0 0 O88609 1.85e-74 LIM homeobox transcription factor 1-beta (LIM/homeobox protein 1.2) (LMX-1.2) (LIM/homeobox protein LMX1B) Mus musculus (Mouse) camera-type eye development [GO:0043010]; cell population proliferation [GO:0008283]; central nervous system neuron development [GO:0021954]; cerebellum morphogenesis [GO:0021587]; collagen fibril organization [GO:0030199]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral pattern formation [GO:0009953]; embryonic limb morphogenesis [GO:0030326]; limb morphogenesis [GO:0035108]; locomotory behavior [GO:0007626]; memory [GO:0007613]; midbrain development [GO:0030901]; neuron differentiation [GO:0030182]; neuron migration [GO:0001764]; olfactory behavior [GO:0042048]; organ growth [GO:0035265]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of autophagy [GO:0010506]; regulation of DNA-templated transcription [GO:0006355]; regulation of gene expression [GO:0010468]; regulation of intracellular transport [GO:0032386]; regulation of transcription by RNA polymerase II [GO:0006357]; synapse organization [GO:0050808]; trabecular meshwork development [GO:0002930] GO:0000977; GO:0000981; GO:0001228; GO:0001764; GO:0002930; GO:0003700; GO:0005634; GO:0006355; GO:0006357; GO:0007613; GO:0007626; GO:0008283; GO:0009953; GO:0010468; GO:0010506; GO:0021587; GO:0021954; GO:0030182; GO:0030199; GO:0030326; GO:0030901; GO:0032386; GO:0035108; GO:0035265; GO:0042048; GO:0043010; GO:0045944; GO:0046872; GO:0050808; GO:0071542; GO:1990837 5785 XM_044327338.1 1 8 0 0 44 NA NA NA NA NA NA 5786 XM_029341423.2 90 67 17 93 98 NA NA NA NA NA NA 5787 XM_029339836.2 50 73 83 80 36 Q7LGC8 1.79e-25 Carbohydrate sulfotransferase 3 (EC 2.8.2.17) (EC 2.8.2.21) (Chondroitin 6-O-sulfotransferase 1) (C6ST-1) (Chondroitin 6-sulfotransferase) (C6ST) (Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 0) (GST-0) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; chondroitin sulfate biosynthetic process [GO:0030206]; N-acetylglucosamine metabolic process [GO:0006044]; sulfur compound metabolic process [GO:0006790]; T cell homeostasis [GO:0043029] GO:0000139; GO:0001517; GO:0005802; GO:0005975; GO:0006044; GO:0006790; GO:0008459; GO:0030206; GO:0043029; GO:0050698 5788 XM_029346681.2 26 68 16 38 49 Q8BH75 2.66e-23 E3 ubiquitin-protein ligase NRDP1 (EC 2.3.2.27) (RING finger protein 41) (RING-type E3 ubiquitin transferase NRDP1) Mus musculus (Mouse) autophagy [GO:0006914]; extrinsic apoptotic signaling pathway [GO:0097191]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of mitophagy [GO:1901525]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; proteasomal protein catabolic process [GO:0010498]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of lymphocyte differentiation [GO:0045619]; regulation of MAPK cascade [GO:0043408]; regulation of myeloid cell differentiation [GO:0045637]; regulation of protein kinase B signaling [GO:0051896]; regulation of reactive oxygen species metabolic process [GO:2000377] GO:0000209; GO:0004842; GO:0005128; GO:0005135; GO:0006914; GO:0008270; GO:0008285; GO:0010498; GO:0016567; GO:0019904; GO:0030336; GO:0030971; GO:0031267; GO:0042802; GO:0043408; GO:0045619; GO:0045637; GO:0045732; GO:0048471; GO:0051865; GO:0051896; GO:0061630; GO:0071782; GO:0097191; GO:1901525; GO:2000377; GO:2000379 5789 XM_044325431.1 9 4 5 33 122 Q5XIT9 3.99e-106 Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCase subunit beta) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 2) (3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta) Rattus norvegicus (Rat) coenzyme A metabolic process [GO:0015936]; leucine catabolic process [GO:0006552] GO:0002169; GO:0004485; GO:0005524; GO:0005739; GO:0005759; GO:0006552; GO:0015936; GO:1905202 5790 XR_006391558.1 252 64 0 0 0 NA NA NA NA NA NA 5791 XM_044328432.1 141 59 51 75 109 A6NHR9 0 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 (SMC hinge domain-containing protein 1) (EC 3.6.1.-) Homo sapiens (Human) chromosome organization [GO:0051276]; dosage compensation by inactivation of X chromosome [GO:0009048]; double-strand break repair [GO:0006302]; inactivation of X chromosome by heterochromatin formation [GO:0060820]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; nose development [GO:0043584]; positive regulation of DNA repair [GO:0045739]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034] GO:0001740; GO:0003677; GO:0005524; GO:0006302; GO:0009048; GO:0016887; GO:0035861; GO:0042803; GO:0043584; GO:0045739; GO:0051276; GO:0060820; GO:2000042; GO:2001034 5792 XM_029349392.2 72 2 0 2 0 NA NA NA NA NA NA 5793 XM_029331557.2 87 153 98 94 69 NA NA NA NA NA NA 5794 XM_029344621.2 664 728 587 326 669 Q9MYU8 4.79e-92 Band 4.1-like protein 5 (Erythrocyte membrane protein band 4.1-like 5) Canis lupus familiaris (Dog) (Canis familiaris) actomyosin structure organization [GO:0031032] GO:0001917; GO:0005737; GO:0005856; GO:0005886; GO:0005912; GO:0008092; GO:0031032 5795 XM_029358183.2 657 640 344 377 738 NA NA NA NA NA NA 5796 XM_044312968.1 952 451 767 1164 1075 Q12882 0 Dihydropyrimidine dehydrogenase [NADP(+)] (DHPDHase) (DPD) (EC 1.3.1.2) (Dihydrothymine dehydrogenase) (Dihydrouracil dehydrogenase) Homo sapiens (Human) beta-alanine biosynthetic process [GO:0019483]; CMP catabolic process [GO:0006248]; dCMP catabolic process [GO:0006249]; dUMP catabolic process [GO:0046079]; purine nucleobase catabolic process [GO:0006145]; pyrimidine nucleobase catabolic process [GO:0006208]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; UMP catabolic process [GO:0046050]; uracil catabolic process [GO:0006212] GO:0002058; GO:0005737; GO:0005829; GO:0006145; GO:0006208; GO:0006210; GO:0006212; GO:0006214; GO:0006248; GO:0006249; GO:0017113; GO:0019483; GO:0042803; GO:0046050; GO:0046079; GO:0046872; GO:0050660; GO:0050661; GO:0051536; GO:0051539 5797 XM_044327263.1 0 17 0 0 0 NA NA NA NA NA NA 5798 XM_044328337.1 201 127 47 111 51 Q9BX70 3.06e-53 BTB/POZ domain-containing protein 2 Homo sapiens (Human) neurogenesis [GO:0022008] GO:0000932; GO:0005829; GO:0022008 5799 XM_029352455.2 155 0 0 0 202 A5D7F5 7.54e-82 DnaJ homolog subfamily C member 27 (Rab and DnaJ domain-containing protein) Bos taurus (Bovine) intracellular protein transport [GO:0006886] GO:0003924; GO:0005525; GO:0005634; GO:0006886 5800 XM_029323721.2 2051 1332 1324 1533 1259 E1BD52 9.57e-157 Transmembrane protein 245 Bos taurus (Bovine) NA GO:0016020 5801 XM_029357047.2 1303 1097 643 1032 1249 Q96EB6 1.82e-148 NAD-dependent protein deacetylase sirtuin-1 (hSIRT1) (EC 2.3.1.286) (NAD-dependent protein deacylase sirtuin-1) (EC 2.3.1.-) (Regulatory protein SIR2 homolog 1) (SIR2-like protein 1) (hSIR2) [Cleaved into: SirtT1 75 kDa fragment (75SirT1)] Homo sapiens (Human) angiogenesis [GO:0001525]; behavioral response to starvation [GO:0042595]; cellular glucose homeostasis [GO:0001678]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to glucose starvation [GO:0042149]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; cellular triglyceride homeostasis [GO:0035356]; cholesterol homeostasis [GO:0042632]; chromatin organization [GO:0006325]; circadian regulation of gene expression [GO:0032922]; DNA methylation-dependent heterochromatin formation [GO:0006346]; DNA synthesis involved in DNA repair [GO:0000731]; energy homeostasis [GO:0097009]; fatty acid homeostasis [GO:0055089]; heterochromatin formation [GO:0031507]; histone deacetylation [GO:0016575]; histone H3 deacetylation [GO:0070932]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; leptin-mediated signaling pathway [GO:0033210]; macrophage differentiation [GO:0030225]; muscle organ development [GO:0007517]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cAMP-dependent protein kinase activity [GO:2000480]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell growth [GO:0030308]; negative regulation of cellular response to testosterone stimulus [GO:2000655]; negative regulation of cellular senescence [GO:2000773]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of helicase activity [GO:0051097]; negative regulation of histone H3-K14 acetylation [GO:0071441]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; negative regulation of histone H4-K16 acetylation [GO:2000619]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of neuron death [GO:1901215]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of peptidyl-lysine acetylation [GO:2000757]; negative regulation of phosphorylation [GO:0042326]; negative regulation of prostaglandin biosynthetic process [GO:0031393]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; ovulation from ovarian follicle [GO:0001542]; peptidyl-lysine acetylation [GO:0018394]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of adipose tissue development [GO:1904179]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cAMP-dependent protein kinase activity [GO:2000481]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular senescence [GO:2000774]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of DNA repair [GO:0045739]; positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902237]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of gluconeogenesis [GO:0045722]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of histone H3-K9 methylation [GO:0051574]; positive regulation of histone methylation [GO:0031062]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of macroautophagy [GO:0016239]; positive regulation of macrophage apoptotic process [GO:2000111]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell differentiation [GO:0051152]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deacetylation [GO:0006476]; protein depropionylation [GO:0106230]; protein destabilization [GO:0031648]; protein ubiquitination [GO:0016567]; pyrimidine dimer repair by nucleotide-excision repair [GO:0000720]; rDNA heterochromatin formation [GO:0000183]; regulation of apoptotic process [GO:0042981]; regulation of bile acid biosynthetic process [GO:0070857]; regulation of brown fat cell differentiation [GO:0090335]; regulation of cell population proliferation [GO:0042127]; regulation of cellular response to heat [GO:1900034]; regulation of centrosome duplication [GO:0010824]; regulation of endodeoxyribonuclease activity [GO:0032071]; regulation of glucose metabolic process [GO:0010906]; regulation of lipid storage [GO:0010883]; regulation of mitotic cell cycle [GO:0007346]; regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035358]; regulation of protein serine/threonine kinase activity [GO:0071900]; regulation of smooth muscle cell apoptotic process [GO:0034391]; regulation of transcription by glucose [GO:0046015]; response to hydrogen peroxide [GO:0042542]; response to insulin [GO:0032868]; response to leptin [GO:0044321]; response to oxidative stress [GO:0006979]; single strand break repair [GO:0000012]; spermatogenesis [GO:0007283]; stress-induced premature senescence [GO:0090400]; transforming growth factor beta receptor signaling pathway [GO:0007179]; triglyceride mobilization [GO:0006642]; UV-damage excision repair [GO:0070914]; white fat cell differentiation [GO:0050872] GO:0000012; GO:0000122; GO:0000183; GO:0000720; GO:0000731; GO:0000785; GO:0000791; GO:0000792; GO:0000978; GO:0001525; GO:0001542; GO:0001650; GO:0001678; GO:0001934; GO:0001938; GO:0002039; GO:0002821; GO:0003713; GO:0003714; GO:0004407; GO:0005634; GO:0005635; GO:0005637; GO:0005654; GO:0005677; GO:0005730; GO:0005737; GO:0005739; GO:0005829; GO:0006325; GO:0006346; GO:0006476; GO:0006642; GO:0006974; GO:0006979; GO:0007179; GO:0007283; GO:0007346; GO:0007517; GO:0008022; GO:0008284; GO:0009267; GO:0010629; GO:0010824; GO:0010875; GO:0010883; GO:0010906; GO:0014068; GO:0016239; GO:0016567; GO:0016575; GO:0016605; GO:0016922; GO:0017136; GO:0018394; GO:0019213; GO:0019899; GO:0030225; GO:0030308; GO:0030512; GO:0031062; GO:0031065; GO:0031393; GO:0031507; GO:0031648; GO:0032007; GO:0032071; GO:0032088; GO:0032868; GO:0032922; GO:0033210; GO:0033553; GO:0033558; GO:0034391; GO:0034979; GO:0034983; GO:0035356; GO:0035358; GO:0042127; GO:0042149; GO:0042326; GO:0042393; GO:0042542; GO:0042595; GO:0042632; GO:0042771; GO:0042802; GO:0042981; GO:0043065; GO:0043066; GO:0043124; GO:0043161; GO:0043280; GO:0043398; GO:0043425; GO:0043433; GO:0043518; GO:0043536; GO:0044321; GO:0045348; GO:0045599; GO:0045722; GO:0045739; GO:0045766; GO:0045786; GO:0045892; GO:0045944; GO:0046015; GO:0046628; GO:0046872; GO:0046969; GO:0050872; GO:0051019; GO:0051097; GO:0051152; GO:0051574; GO:0051898; GO:0055089; GO:0060766; GO:0060907; GO:0061773; GO:0070301; GO:0070403; GO:0070857; GO:0070914; GO:0070932; GO:0071356; GO:0071441; GO:0071456; GO:0071479; GO:0071900; GO:0090335; GO:0090400; GO:0097009; GO:0106230; GO:0106231; GO:0140297; GO:0160012; GO:1900034; GO:1900113; GO:1901215; GO:1901984; GO:1902166; GO:1902176; GO:1902237; GO:1904179; GO:1990254; GO:1990830; GO:1990841; GO:2000111; GO:2000480; GO:2000481; GO:2000619; GO:2000655; GO:2000757; GO:2000773; GO:2000774 5802 XR_006391391.1 34 0 37 93 11 NA NA NA NA NA NA 5803 XM_044322643.1 2662 3069 494 598 1155 NA NA NA NA NA NA 5804 XM_029346307.2 76 0 90 193 0 Q6L8S8 6.45e-55 Beta-1,4-N-acetylgalactosaminyltransferase 3 (Beta4GalNAc-T3) (Beta4GalNAcT3) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase III) (N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 2) (NGalNAc-T2) Mus musculus (Mouse) chondroitin sulfate biosynthetic process [GO:0030206] GO:0005794; GO:0008376; GO:0030206; GO:0032580; GO:0033842; GO:0043231; GO:0047238 5805 XM_029356757.2 151 72 0 294 314 Q8NHP1 1.5e-88 Aflatoxin B1 aldehyde reductase member 4 (EC 1.-.-.-) (AFB1 aldehyde reductase 3) (AFB1-AR 3) (Aldoketoreductase 7-like) Homo sapiens (Human) NA GO:0004033; GO:0005737; GO:0005829; GO:0070062 5806 XM_029356757.2 151 72 0 294 314 Q8NHP1 9.64e-46 Aflatoxin B1 aldehyde reductase member 4 (EC 1.-.-.-) (AFB1 aldehyde reductase 3) (AFB1-AR 3) (Aldoketoreductase 7-like) Homo sapiens (Human) NA GO:0004033; GO:0005737; GO:0005829; GO:0070062 5807 XM_029332469.2 333 158 292 276 198 E7FAM5 1.2e-58 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 5808 XM_029332469.2 333 158 292 276 198 E7FAM5 5.21e-32 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 5809 XM_029332469.2 333 158 292 276 198 E7FAM5 3.4e-24 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 5810 XM_029339052.2 226 97 96 283 241 Q7TN88 0 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 5811 XM_029345610.2 4 6 0 0 0 NA NA NA NA NA NA 5812 XR_006395622.1 451 405 263 484 424 NA NA NA NA NA NA 5813 XR_003823452.2 16 3 3 9 3 NA NA NA NA NA NA 5814 XM_029347568.2 44 354 81 368 184 NA NA NA NA NA NA 5815 XR_006394544.1 25 20 15 3 12 NA NA NA NA NA NA 5816 XM_029338105.2 46 44 64 48 97 NA NA NA NA NA NA 5817 XR_006398179.1 15 2 8 8 0 NA NA NA NA NA NA 5818 XM_029339043.2 110 136 57 67 74 NA NA NA NA NA NA 5819 XR_006396798.1 23 2 0 0 0 Q96DM1 2.41e-57 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 5820 XM_044307668.1 41 24 31 27 38 NA NA NA NA NA NA 5821 XM_029335656.2 3453 5960 5270 4597 1224 P02362 1.37e-96 40S ribosomal protein S7 (40S ribosomal protein S8) Xenopus laevis (African clawed frog) translation [GO:0006412] GO:0003735; GO:0005840; GO:0006412; GO:1990904 5822 XM_044317878.1 0 32 86 72 0 Q5E9T8 1.21e-64 Mevalonate kinase (MK) (EC 2.7.1.36) Bos taurus (Bovine) cholesterol biosynthetic process [GO:0006695]; isopentenyl diphosphate biosynthetic process, mevalonate pathway [GO:0019287]; negative regulation of inflammatory response [GO:0050728]; phosphorylation [GO:0016310] GO:0000287; GO:0004496; GO:0005524; GO:0005777; GO:0005829; GO:0006695; GO:0016310; GO:0019287; GO:0042802; GO:0050728 5823 XM_029348242.2 1265 1077 693 1579 1553 A0A1L5YRA2 2.37e-123 Triosephosphate isomerase (TIM) (EC 5.3.1.1) (Allergen Scy p 8) (Methylglyoxal synthase) (EC 4.2.3.3) (Triose-phosphate isomerase) (allergen Scy p 8.0101) Scylla paramamosain (Mud crab) gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242] GO:0004807; GO:0005737; GO:0006094; GO:0006096; GO:0008929; GO:0019242; GO:0019863; GO:0042803 5824 XR_006391831.1 376 99 253 219 833 NA NA NA NA NA NA 5825 XM_029350718.2 295 163 65 644 744 O14653 2.45e-49 Golgi SNAP receptor complex member 2 (27 kDa Golgi SNARE protein) (Membrin) Homo sapiens (Human) intra-Golgi vesicle-mediated transport [GO:0006891]; protein transport [GO:0015031]; vesicle fusion [GO:0006906] GO:0000139; GO:0000149; GO:0005484; GO:0005789; GO:0005794; GO:0006891; GO:0006906; GO:0012507; GO:0015031; GO:0016020; GO:0031201; GO:0031902; GO:0033116 5826 XM_029329765.2 4903 3728 2125 4058 2917 O35547 0 Long-chain-fatty-acid--CoA ligase 4 (EC 6.2.1.3) (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain acyl-CoA synthetase 4) (LACS 4) Rattus norvegicus (Rat) dendritic spine development [GO:0060996]; embryonic process involved in female pregnancy [GO:0060136]; fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; lipid metabolic process [GO:0006629]; long-chain fatty acid metabolic process [GO:0001676]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]; neuron differentiation [GO:0030182]; positive regulation of insulin secretion [GO:0032024]; response to interleukin-15 [GO:0070672]; response to nutrient [GO:0007584]; triglyceride biosynthetic process [GO:0019432] GO:0001676; GO:0004467; GO:0005524; GO:0005737; GO:0005739; GO:0005741; GO:0005777; GO:0005778; GO:0005783; GO:0005789; GO:0005811; GO:0005886; GO:0006629; GO:0006631; GO:0007584; GO:0015908; GO:0016020; GO:0019432; GO:0030182; GO:0031957; GO:0031966; GO:0032024; GO:0035336; GO:0035338; GO:0043025; GO:0044233; GO:0047676; GO:0060136; GO:0060996; GO:0070672 5827 XM_029338443.2 73 105 18 51 23 A4FUP9 3.4e-93 Glycosyltransferase 1 domain-containing protein 1 (EC 2.4.-.-) Mus musculus (Mouse) NA GO:0005576; GO:0005829; GO:0016757 5828 XM_029335568.2 1204 1413 1776 1736 886 P55006 4.99e-77 Retinol dehydrogenase 7 (EC 1.1.1.105) (Retinol dehydrogenase 3) (Retinol dehydrogenase type III) (RODH III) Rattus norvegicus (Rat) retinol metabolic process [GO:0042572]; steroid metabolic process [GO:0008202] GO:0004745; GO:0005783; GO:0008202; GO:0016491; GO:0042572; GO:0043231 5829 XM_029352263.2 32 0 21 35 0 NA NA NA NA NA NA 5830 XM_029352935.2 332 249 117 220 250 B3RXR7 0 Translation factor GUF1 homolog, mitochondrial (EC 3.6.5.-) (Elongation factor 4 homolog) (EF-4) (GTPase GUF1 homolog) (Ribosomal back-translocase) Trichoplax adhaerens (Trichoplax reptans) positive regulation of translation [GO:0045727]; translation [GO:0006412] GO:0003924; GO:0005525; GO:0005739; GO:0005743; GO:0005759; GO:0006412; GO:0043022; GO:0045727; GO:0097177 5831 XM_044312988.1 668 852 440 720 1041 NA NA NA NA NA NA 5832 XM_044311544.1 8 0 1 0 9 NA NA NA NA NA NA 5833 XM_029356726.2 505 506 553 525 638 Q0V8A3 1.74e-82 Cytosolic arginine sensor for mTORC1 subunit 1 (GATS-like protein 3) Bos taurus (Bovine) cellular response to L-arginine [GO:1903577]; negative regulation of TORC1 signaling [GO:1904262]; regulation of intracellular signal transduction [GO:1902531] GO:0005829; GO:0034618; GO:0042802; GO:0061700; GO:0140311; GO:1902531; GO:1903577; GO:1904262 5834 XM_029346982.2 304 132 91 152 94 A1L1W9 1.68e-22 Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10) Danio rerio (Zebrafish) (Brachydanio rerio) aromatic amino acid transport [GO:0015801]; thyroid hormone transport [GO:0070327] GO:0005302; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0070327 5835 XM_029335629.2 257 185 131 168 232 Q9PTD5 5.54e-24 Mitochondrial fission regulator 1 (Chondrocyte protein with a poly-proline region) Gallus gallus (Chicken) aerobic respiration [GO:0009060]; mitochondrial fission [GO:0000266]; mitochondrion organization [GO:0007005] GO:0000266; GO:0005739; GO:0007005; GO:0009060 5836 XM_029341432.2 213 99 181 379 373 Q64332 1.41e-134 Synapsin-2 (Synapsin II) Mus musculus (Mouse) calcium-ion regulated exocytosis [GO:0017156]; neurotransmitter secretion [GO:0007269]; synaptic vesicle clustering [GO:0097091]; synaptic vesicle cycle [GO:0099504] GO:0005524; GO:0005886; GO:0007269; GO:0008021; GO:0014069; GO:0017156; GO:0030672; GO:0031201; GO:0042802; GO:0043209; GO:0045202; GO:0048306; GO:0097091; GO:0098685; GO:0098850; GO:0098978; GO:0099504 5837 XR_003822849.2 0 51 0 20 34 NA NA NA NA NA NA 5838 XM_029334144.2 482 272 238 339 281 Q6DDY9 1.28e-51 28S ribosomal protein S7, mitochondrial (MRP-S7) (S7mt) Xenopus laevis (African clawed frog) mitochondrial translation [GO:0032543] GO:0003735; GO:0005763; GO:0032543 5839 XM_044309701.1 1 3 0 0 10 P81274 5.77e-43 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 5840 XM_044309701.1 1 3 0 0 10 P81274 9.66e-42 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 5841 XM_044309701.1 1 3 0 0 10 P81274 3.61e-37 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 5842 XM_029358548.2 9913 16877 9020 10132 6304 B3EWY7 0 Acidic skeletal organic matrix protein (Acidic SOMP) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 5843 XM_044328577.1 0 0 39 0 57 P51892 0 DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1) Xenopus laevis (African clawed frog) cell cycle [GO:0007049]; cell division [GO:0051301]; DNA biosynthetic process [GO:0071897]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260] GO:0003677; GO:0003910; GO:0005524; GO:0005634; GO:0006260; GO:0006281; GO:0006310; GO:0007049; GO:0046872; GO:0051301; GO:0071897 5844 XM_029341306.2 433 260 221 314 321 Q86WZ0 1.14e-94 HEAT repeat-containing protein 4 Homo sapiens (Human) NA GO:0016491 5845 XR_003825253.2 14 5 5 33 5 NA NA NA NA NA NA 5846 XM_029335370.2 11672 14521 6714 10090 8242 P79781 3.82e-77 Ubiquitin-40S ribosomal protein S27a (Ubiquitin carboxyl extension protein 80) [Cleaved into: Ubiquitin; 40S ribosomal protein S27a] Gallus gallus (Chicken) modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]; translation [GO:0006412] GO:0003735; GO:0005634; GO:0005654; GO:0005737; GO:0006412; GO:0016567; GO:0019941; GO:0022627; GO:0031386; GO:0031625; GO:0046872 5847 XM_029326758.2 158 42 122 40 47 O00370 1.7e-25 LINE-1 retrotransposable element ORF2 protein (ORF2p) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)] Homo sapiens (Human) DNA recombination [GO:0006310]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; reverse transcription involved in RNA-mediated transposition [GO:0032199]; transposition, RNA-mediated [GO:0032197] GO:0003723; GO:0003964; GO:0006310; GO:0009036; GO:0032197; GO:0032199; GO:0046872; GO:0090305 5848 XM_044319780.1 3421 2151 1944 3325 3189 Q06A37 0 Chromodomain-helicase-DNA-binding protein 7 (CHD-7) (EC 3.6.4.12) (ATP-dependent helicase CHD7) Gallus gallus (Chicken) adult heart development [GO:0007512]; adult walking behavior [GO:0007628]; aorta morphogenesis [GO:0035909]; atrioventricular canal development [GO:0036302]; blood circulation [GO:0008015]; blood vessel remodeling [GO:0001974]; cardiac septum morphogenesis [GO:0060411]; central nervous system development [GO:0007417]; chordate embryonic development [GO:0043009]; chromatin remodeling [GO:0006338]; cognition [GO:0050890]; cranial nerve development [GO:0021545]; embryonic hindlimb morphogenesis [GO:0035116]; epithelium development [GO:0060429]; face development [GO:0060324]; female genitalia development [GO:0030540]; heart morphogenesis [GO:0003007]; inner ear morphogenesis [GO:0042472]; innervation [GO:0060384]; nose development [GO:0043584]; olfactory behavior [GO:0042048]; olfactory bulb development [GO:0021772]; olfactory nerve development [GO:0021553]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression [GO:0010468]; regulation of growth hormone secretion [GO:0060123]; regulation of neurogenesis [GO:0050767]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; response to bacterium [GO:0009617]; retina development in camera-type eye [GO:0060041]; right ventricular compact myocardium morphogenesis [GO:0003226]; rRNA processing [GO:0006364]; secondary palate development [GO:0062009]; semicircular canal morphogenesis [GO:0048752]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]; T cell differentiation [GO:0030217]; transcription by RNA polymerase II [GO:0006366]; ventricular trabecula myocardium morphogenesis [GO:0003222] GO:0000785; GO:0000978; GO:0001501; GO:0001974; GO:0003007; GO:0003222; GO:0003226; GO:0003677; GO:0003682; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0006338; GO:0006364; GO:0006366; GO:0007417; GO:0007512; GO:0007605; GO:0007628; GO:0008015; GO:0009617; GO:0010468; GO:0010880; GO:0016887; GO:0021545; GO:0021553; GO:0021772; GO:0030217; GO:0030540; GO:0035116; GO:0035909; GO:0036302; GO:0040018; GO:0042048; GO:0042393; GO:0042472; GO:0043009; GO:0043584; GO:0045944; GO:0048752; GO:0050767; GO:0050890; GO:0060041; GO:0060123; GO:0060324; GO:0060384; GO:0060411; GO:0060429; GO:0062009; GO:0140658; GO:1990841 5849 XM_044320631.1 99 70 66 141 124 Q7RTR2 1.45e-48 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 5850 XM_044320631.1 99 70 66 141 124 Q7RTR2 2.13e-48 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 5851 XM_044320631.1 99 70 66 141 124 Q7RTR2 4.5e-42 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 5852 XM_044320631.1 99 70 66 141 124 Q7RTR2 3.49e-35 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 5853 XM_044320631.1 99 70 66 141 124 Q7RTR2 1.17e-30 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 5854 XM_044320631.1 99 70 66 141 124 Q7RTR2 6.3e-24 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 5855 XM_044316156.1 8 0 7 6 34 NA NA NA NA NA NA 5856 XM_044323337.1 199 55 83 179 204 Q9H9B1 1.03e-148 Histone-lysine N-methyltransferase EHMT1 (EC 2.1.1.-) (EC 2.1.1.367) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a-like protein 1) (GLP) (GLP1) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Lysine N-methyltransferase 1D) Homo sapiens (Human) chromatin organization [GO:0006325]; DNA methylation [GO:0006306]; facultative heterochromatin formation [GO:0140718]; histone H3-K9 methylation [GO:0051567]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-lysine dimethylation [GO:0018027]; peptidyl-lysine monomethylation [GO:0018026]; positive regulation of cold-induced thermogenesis [GO:0120162]; regulation of embryonic development [GO:0045995]; regulation of histone H3-K9 methylation [GO:0051570] GO:0000122; GO:0000785; GO:0001222; GO:0002039; GO:0005634; GO:0005654; GO:0006306; GO:0006325; GO:0008168; GO:0008270; GO:0016279; GO:0016604; GO:0018024; GO:0018026; GO:0018027; GO:0045892; GO:0045995; GO:0046974; GO:0046976; GO:0051567; GO:0051570; GO:0070742; GO:0120162; GO:0140718; GO:0140947 5857 XM_029347944.2 38 41 7 103 10 NA NA NA NA NA NA 5858 XM_044326259.1 7 0 2 0 0 NA NA NA NA NA NA 5859 XR_006397525.1 194 83 254 174 655 NA NA NA NA NA NA 5860 XM_044324371.1 165 43 47 69 314 NA NA NA NA NA NA 5861 XM_029356725.2 4226 4061 2942 4154 3032 Q5R8D0 5.31e-166 UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP-N-acetylglucosamine 4-epimerase) (UDP-GlcNAc 4-epimerase) (EC 5.1.3.7) (UDP-galactosamine 4-epimerase) (UDP-GalNAc 4-epimerase) (UDP-galactose 4-epimerase) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) galactose metabolic process [GO:0006012] GO:0003974; GO:0003978; GO:0006012 5862 XM_029335891.2 1220 1144 717 1067 931 Q07066 3.18e-44 Peroxisomal membrane protein 2 (22 kDa peroxisomal membrane protein) Rattus norvegicus (Rat) NA GO:0005737; GO:0005739; GO:0005777; GO:0005778; GO:0032991 5863 XR_003825190.2 1130 4414 1700 1723 508 NA NA NA NA NA NA 5864 XM_044308007.1 4 19 1 0 0 NA NA NA NA NA NA 5865 XM_044316353.1 1739 2812 2180 2133 103 NA NA NA NA NA NA 5866 XM_029338537.2 159 302 126 92 118 Q96K80 1.01e-31 Zinc finger CCCH domain-containing protein 10 Homo sapiens (Human) negative regulation of miRNA maturation [GO:1903799]; post-transcriptional regulation of gene expression [GO:0010608]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381] GO:0000381; GO:0003723; GO:0005654; GO:0005737; GO:0010608; GO:0035198; GO:0046872; GO:1903799 5867 XM_044321608.1 152 54 9 283 0 NA NA NA NA NA NA 5868 XM_029324202.2 1287 1069 981 1266 1651 NA NA NA NA NA NA 5869 XM_029349171.2 0 0 14 6 34 Q9CPV7 1.24e-98 Palmitoyltransferase ZDHHC6 (EC 2.3.1.225) (Stearoyltransferase ZDHHC6) (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 6) (DHHC-6) Mus musculus (Mouse) peptidyl-L-cysteine S-palmitoylation [GO:0018230]; positive regulation of mitochondrial fusion [GO:0010636]; protein palmitoylation [GO:0018345]; protein stearoylation [GO:0140438]; protein targeting to membrane [GO:0006612] GO:0005783; GO:0005789; GO:0005794; GO:0006612; GO:0010636; GO:0016409; GO:0018230; GO:0018345; GO:0019706; GO:0140438; GO:0140439 5870 XM_029335606.2 230 139 236 437 219 Q00174 3.64e-167 Laminin subunit alpha (Laminin A chain) Drosophila melanogaster (Fruit fly) animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; basement membrane organization [GO:0071711]; cell adhesion mediated by integrin [GO:0033627]; dorsal trunk growth, open tracheal system [GO:0035001]; heart development [GO:0007507]; melanotic encapsulation of foreign target [GO:0035011]; mesoderm development [GO:0007498]; negative regulation of synaptic assembly at neuromuscular junction [GO:0045886]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888] GO:0005102; GO:0005576; GO:0005604; GO:0007411; GO:0007498; GO:0007507; GO:0008021; GO:0009887; GO:0009888; GO:0030155; GO:0030334; GO:0030424; GO:0033627; GO:0034446; GO:0035001; GO:0035011; GO:0036062; GO:0045886; GO:0045995; GO:0062023; GO:0071711 5871 XM_029335606.2 230 139 236 437 219 Q00174 1.71e-133 Laminin subunit alpha (Laminin A chain) Drosophila melanogaster (Fruit fly) animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; basement membrane organization [GO:0071711]; cell adhesion mediated by integrin [GO:0033627]; dorsal trunk growth, open tracheal system [GO:0035001]; heart development [GO:0007507]; melanotic encapsulation of foreign target [GO:0035011]; mesoderm development [GO:0007498]; negative regulation of synaptic assembly at neuromuscular junction [GO:0045886]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888] GO:0005102; GO:0005576; GO:0005604; GO:0007411; GO:0007498; GO:0007507; GO:0008021; GO:0009887; GO:0009888; GO:0030155; GO:0030334; GO:0030424; GO:0033627; GO:0034446; GO:0035001; GO:0035011; GO:0036062; GO:0045886; GO:0045995; GO:0062023; GO:0071711 5872 XM_029335606.2 230 139 236 437 219 Q00174 6.84e-40 Laminin subunit alpha (Laminin A chain) Drosophila melanogaster (Fruit fly) animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; basement membrane organization [GO:0071711]; cell adhesion mediated by integrin [GO:0033627]; dorsal trunk growth, open tracheal system [GO:0035001]; heart development [GO:0007507]; melanotic encapsulation of foreign target [GO:0035011]; mesoderm development [GO:0007498]; negative regulation of synaptic assembly at neuromuscular junction [GO:0045886]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888] GO:0005102; GO:0005576; GO:0005604; GO:0007411; GO:0007498; GO:0007507; GO:0008021; GO:0009887; GO:0009888; GO:0030155; GO:0030334; GO:0030424; GO:0033627; GO:0034446; GO:0035001; GO:0035011; GO:0036062; GO:0045886; GO:0045995; GO:0062023; GO:0071711 5873 XM_029335606.2 230 139 236 437 219 Q00174 2.07e-30 Laminin subunit alpha (Laminin A chain) Drosophila melanogaster (Fruit fly) animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; basement membrane organization [GO:0071711]; cell adhesion mediated by integrin [GO:0033627]; dorsal trunk growth, open tracheal system [GO:0035001]; heart development [GO:0007507]; melanotic encapsulation of foreign target [GO:0035011]; mesoderm development [GO:0007498]; negative regulation of synaptic assembly at neuromuscular junction [GO:0045886]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888] GO:0005102; GO:0005576; GO:0005604; GO:0007411; GO:0007498; GO:0007507; GO:0008021; GO:0009887; GO:0009888; GO:0030155; GO:0030334; GO:0030424; GO:0033627; GO:0034446; GO:0035001; GO:0035011; GO:0036062; GO:0045886; GO:0045995; GO:0062023; GO:0071711 5874 XM_029335606.2 230 139 236 437 219 Q00174 3.9e-29 Laminin subunit alpha (Laminin A chain) Drosophila melanogaster (Fruit fly) animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; basement membrane organization [GO:0071711]; cell adhesion mediated by integrin [GO:0033627]; dorsal trunk growth, open tracheal system [GO:0035001]; heart development [GO:0007507]; melanotic encapsulation of foreign target [GO:0035011]; mesoderm development [GO:0007498]; negative regulation of synaptic assembly at neuromuscular junction [GO:0045886]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888] GO:0005102; GO:0005576; GO:0005604; GO:0007411; GO:0007498; GO:0007507; GO:0008021; GO:0009887; GO:0009888; GO:0030155; GO:0030334; GO:0030424; GO:0033627; GO:0034446; GO:0035001; GO:0035011; GO:0036062; GO:0045886; GO:0045995; GO:0062023; GO:0071711 5875 XM_029335606.2 230 139 236 437 219 Q00174 2.48e-26 Laminin subunit alpha (Laminin A chain) Drosophila melanogaster (Fruit fly) animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; basement membrane organization [GO:0071711]; cell adhesion mediated by integrin [GO:0033627]; dorsal trunk growth, open tracheal system [GO:0035001]; heart development [GO:0007507]; melanotic encapsulation of foreign target [GO:0035011]; mesoderm development [GO:0007498]; negative regulation of synaptic assembly at neuromuscular junction [GO:0045886]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888] GO:0005102; GO:0005576; GO:0005604; GO:0007411; GO:0007498; GO:0007507; GO:0008021; GO:0009887; GO:0009888; GO:0030155; GO:0030334; GO:0030424; GO:0033627; GO:0034446; GO:0035001; GO:0035011; GO:0036062; GO:0045886; GO:0045995; GO:0062023; GO:0071711 5876 XM_029335606.2 230 139 236 437 219 Q00174 1.32e-25 Laminin subunit alpha (Laminin A chain) Drosophila melanogaster (Fruit fly) animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; basement membrane organization [GO:0071711]; cell adhesion mediated by integrin [GO:0033627]; dorsal trunk growth, open tracheal system [GO:0035001]; heart development [GO:0007507]; melanotic encapsulation of foreign target [GO:0035011]; mesoderm development [GO:0007498]; negative regulation of synaptic assembly at neuromuscular junction [GO:0045886]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888] GO:0005102; GO:0005576; GO:0005604; GO:0007411; GO:0007498; GO:0007507; GO:0008021; GO:0009887; GO:0009888; GO:0030155; GO:0030334; GO:0030424; GO:0033627; GO:0034446; GO:0035001; GO:0035011; GO:0036062; GO:0045886; GO:0045995; GO:0062023; GO:0071711 5877 XM_029335606.2 230 139 236 437 219 Q00174 1.62e-21 Laminin subunit alpha (Laminin A chain) Drosophila melanogaster (Fruit fly) animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; basement membrane organization [GO:0071711]; cell adhesion mediated by integrin [GO:0033627]; dorsal trunk growth, open tracheal system [GO:0035001]; heart development [GO:0007507]; melanotic encapsulation of foreign target [GO:0035011]; mesoderm development [GO:0007498]; negative regulation of synaptic assembly at neuromuscular junction [GO:0045886]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888] GO:0005102; GO:0005576; GO:0005604; GO:0007411; GO:0007498; GO:0007507; GO:0008021; GO:0009887; GO:0009888; GO:0030155; GO:0030334; GO:0030424; GO:0033627; GO:0034446; GO:0035001; GO:0035011; GO:0036062; GO:0045886; GO:0045995; GO:0062023; GO:0071711 5878 XM_029335606.2 230 139 236 437 219 Q00174 4.58e-21 Laminin subunit alpha (Laminin A chain) Drosophila melanogaster (Fruit fly) animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; basement membrane organization [GO:0071711]; cell adhesion mediated by integrin [GO:0033627]; dorsal trunk growth, open tracheal system [GO:0035001]; heart development [GO:0007507]; melanotic encapsulation of foreign target [GO:0035011]; mesoderm development [GO:0007498]; negative regulation of synaptic assembly at neuromuscular junction [GO:0045886]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888] GO:0005102; GO:0005576; GO:0005604; GO:0007411; GO:0007498; GO:0007507; GO:0008021; GO:0009887; GO:0009888; GO:0030155; GO:0030334; GO:0030424; GO:0033627; GO:0034446; GO:0035001; GO:0035011; GO:0036062; GO:0045886; GO:0045995; GO:0062023; GO:0071711 5879 XM_029346420.2 517 358 275 532 586 NA NA NA NA NA NA 5880 XR_006395259.1 155 30 156 159 165 NA NA NA NA NA NA 5881 XM_029331327.2 406 406 149 277 142 Q9YH18 1.16e-61 KH domain-containing RNA-binding protein QKI (Protein quaking) Gallus gallus (Chicken) long-chain fatty acid biosynthetic process [GO:0042759]; mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; myelination [GO:0042552]; positive regulation of gene expression [GO:0010628]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of translation [GO:0006417]; RNA splicing [GO:0008380]; spermatid development [GO:0007286]; vascular associated smooth muscle cell differentiation [GO:0035886]; vasculogenesis [GO:0001570] GO:0001570; GO:0003729; GO:0005634; GO:0005737; GO:0006397; GO:0006417; GO:0007286; GO:0008380; GO:0010628; GO:0017124; GO:0035886; GO:0042552; GO:0042759; GO:0045202; GO:0048024; GO:0051028 5882 XR_006395361.1 112 293 286 390 84 A0A2B4RP11 1.83e-113 NA NA NA NA 5883 XR_006395361.1 112 293 286 390 84 A0A2B4RP11 1.83e-113 NA NA NA NA 5884 XM_029333248.2 2915 2265 1300 2938 2055 Q8VIF7 0 Methanethiol oxidase (MTO) (EC 1.8.3.4) (56 kDa selenium-binding protein) (SBP56) (SP56) (Selenium-binding protein 1) (Selenium-binding protein 2) Rattus norvegicus (Rat) brown fat cell differentiation [GO:0050873]; protein transport [GO:0015031] GO:0005634; GO:0005829; GO:0008430; GO:0015031; GO:0016020; GO:0018549; GO:0050873 5885 XM_029334642.2 114 90 154 112 158 P0CB42 3.31e-63 Nucleic acid dioxygenase ALKBH1 (EC 1.14.11.-) (Alkylated DNA repair protein alkB homolog 1) (Alpha-ketoglutarate-dependent dioxygenase ABH1) (DNA 6mA demethylase) (DNA N6-methyl adenine demethylase ALKBH1) (EC 1.14.11.51) (DNA lyase ABH1) (EC 4.2.99.18) (DNA oxidative demethylase ALKBH1) (EC 1.14.11.33) (mRNA N(3)-methylcytidine demethylase) (EC 1.14.11.-) (tRNA N1-methyl adenine demethylase) (EC 1.14.11.-) Mus musculus (Mouse) cell differentiation [GO:0030154]; developmental growth [GO:0048589]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA demethylation [GO:0080111]; DNA repair [GO:0006281]; in utero embryonic development [GO:0001701]; negative regulation of neuron apoptotic process [GO:0043524]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; oxidative demethylation [GO:0070989]; oxidative RNA demethylation [GO:0035513]; oxidative single-stranded DNA demethylation [GO:0035552]; placenta development [GO:0001890]; regulation of gene expression [GO:0010468]; regulation of mitochondrial translation [GO:0070129]; regulation of translational elongation [GO:0006448]; regulation of translational initiation [GO:0006446]; RNA repair [GO:0042245]; tRNA demethylation [GO:1990983]; tRNA wobble cytosine modification [GO:0002101] GO:0000049; GO:0000791; GO:0001701; GO:0001764; GO:0001890; GO:0002101; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005783; GO:0006281; GO:0006307; GO:0006446; GO:0006448; GO:0008198; GO:0010468; GO:0016706; GO:0030154; GO:0031175; GO:0035513; GO:0035515; GO:0035516; GO:0035552; GO:0042056; GO:0042245; GO:0043524; GO:0048589; GO:0070129; GO:0070579; GO:0070989; GO:0080111; GO:0140078; GO:1990983; GO:1990984 5886 XM_044310282.1 0 24 4 0 14 NA NA NA NA NA NA 5887 XM_044313733.1 5033 3645 2337 5187 4390 Q9W735 1.29e-86 Prominin-1-A (Prominin-like protein 1) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005783; GO:0005793; GO:0005886; GO:0005902; GO:0005929; GO:0009986; GO:0015485; GO:0016324; GO:0031528; GO:0071914 5888 XM_029349849.2 545 159 154 145 401 NA NA NA NA NA NA 5889 XM_029332579.2 2086 1829 1356 1503 1297 NA NA NA NA NA NA 5890 XM_029336254.2 11 2 30 19 44 F1PZV2 3.27e-21 Major facilitator superfamily domain-containing protein 12 Canis lupus familiaris (Dog) (Canis familiaris) carbohydrate transport [GO:0008643]; cysteine transmembrane transport [GO:1903712]; melanin biosynthetic process [GO:0042438]; organic substance transport [GO:0071702]; pigment metabolic process involved in pigmentation [GO:0043474]; regulation of melanin biosynthetic process [GO:0048021] GO:0005764; GO:0005765; GO:0005886; GO:0008643; GO:0015293; GO:0033162; GO:0033229; GO:0042438; GO:0043474; GO:0048021; GO:0071702; GO:1903712 5891 XM_044326056.1 21 6 28 22 36 NA NA NA NA NA NA 5892 XM_029342070.2 228 120 236 223 206 NA NA NA NA NA NA 5893 XM_044307925.1 0 0 6 0 0 NA NA NA NA NA NA 5894 XR_006397585.1 880 425 318 960 556 NA NA NA NA NA NA 5895 XM_029348935.2 53 57 77 104 159 P18505 3.02e-78 Gamma-aminobutyric acid receptor subunit beta-1 (GABA(A) receptor subunit beta-1) Homo sapiens (Human) cellular response to histamine [GO:0071420]; central nervous system neuron development [GO:0021954]; chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid signaling pathway [GO:0007214]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; nervous system process [GO:0050877]; ovulation cycle [GO:0042698]; regulation of membrane potential [GO:0042391]; response to progesterone [GO:0032570]; response to toxic substance [GO:0009636]; signal transduction [GO:0007165] GO:0004890; GO:0005231; GO:0005635; GO:0005737; GO:0005886; GO:0006811; GO:0007165; GO:0007214; GO:0007268; GO:0009636; GO:0015276; GO:0021954; GO:0022851; GO:0030425; GO:0030594; GO:0032570; GO:0034220; GO:0034707; GO:0042391; GO:0042698; GO:0043005; GO:0045202; GO:0048787; GO:0050811; GO:0050877; GO:0071420; GO:0098685; GO:0098982; GO:0099507; GO:0099634; GO:0150047; GO:1902476; GO:1902711; GO:1904315 5896 XM_029355525.2 5424 5490 2805 5885 2990 NA NA NA NA NA NA 5897 XM_029357841.2 1300 1661 2484 2310 2445 Q8N0W3 0 L-fucose kinase (Fucokinase) (EC 2.7.1.52) Homo sapiens (Human) carbohydrate phosphorylation [GO:0046835]; GDP-L-fucose salvage [GO:0042352]; response to dopamine [GO:1903350] GO:0005524; GO:0005829; GO:0042352; GO:0046835; GO:0050201; GO:1903350 5898 XM_029336596.2 318 1211 195 169 704 NA NA NA NA NA NA 5899 XM_044318749.1 0 0 60 0 168 P52826 0 Carnitine O-acetyltransferase (Carnitine acetylase) (EC 2.3.1.137) (EC 2.3.1.7) (Carnitine acetyltransferase) (CAT) (CrAT) Columba livia (Rock dove) carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; medium-chain fatty acid metabolic process [GO:0051791]; short-chain fatty acid metabolic process [GO:0046459] GO:0003997; GO:0004092; GO:0005743; GO:0005777; GO:0005783; GO:0008458; GO:0019254; GO:0033540; GO:0046459; GO:0051791 5900 XM_044326550.1 589 54 1 5 252 NA NA NA NA NA NA 5901 XM_044317520.1 0 3 1 2 25 NA NA NA NA NA NA 5902 XM_044306946.1 5 1 12 0 0 NA NA NA NA NA NA 5903 XM_029334763.2 15141 11662 6682 11916 9284 Q761V0 3.02e-180 Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5) Mus musculus (Mouse) glycine import across plasma membrane [GO:1903804]; glycine transport [GO:0015816]; neurotransmitter reuptake [GO:0098810]; neurotransmitter uptake [GO:0001504]; sodium ion transmembrane transport [GO:0035725]; synaptic transmission, glycinergic [GO:0060012] GO:0001504; GO:0005768; GO:0005886; GO:0015187; GO:0015375; GO:0015816; GO:0031045; GO:0035725; GO:0042734; GO:0046872; GO:0060012; GO:0098690; GO:0098810; GO:1903804 5904 XR_003824682.2 59 29 72 64 170 NA NA NA NA NA NA 5905 XM_029348369.2 195 164 108 124 244 Q8N7B6 6.94e-78 PACRG-like protein Homo sapiens (Human) NA NA 5906 XM_029347916.2 695 868 168 776 1223 P97779 5.2e-26 Hyaluronan-mediated motility receptor (Intracellular hyaluronic acid-binding protein) (Receptor for hyaluronan-mediated motility) (CD antigen CD168) Rattus norvegicus (Rat) cell-cell signaling [GO:0007267]; cytoskeleton organization [GO:0007010]; endocytosis [GO:0006897]; hyaluronan catabolic process [GO:0030214]; receptor-mediated endocytosis [GO:0006898] GO:0005540; GO:0005737; GO:0005819; GO:0006897; GO:0006898; GO:0007010; GO:0007267; GO:0009986; GO:0030214; GO:0038024 5907 XM_029357596.2 0 0 0 0 166 Q8R4S6 1.92e-31 Aryl hydrocarbon receptor (Ah receptor) (AhR) Mus musculus castaneus (Southeastern Asian house mouse) cell cycle [GO:0007049]; cellular response to 3-methylcholanthrene [GO:1904682]; circadian regulation of gene expression [GO:0032922]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of T cell mediated immune response to tumor cell [GO:0002841]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of adaptive immune response [GO:0002819]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; response to xenobiotic stimulus [GO:0009410]; transcription by RNA polymerase II [GO:0006366] GO:0000976; GO:0002819; GO:0002841; GO:0004879; GO:0005634; GO:0005737; GO:0006355; GO:0006357; GO:0006366; GO:0007049; GO:0009410; GO:0032922; GO:0034751; GO:0034753; GO:0042803; GO:0045892; GO:0045944; GO:0046982; GO:0070888; GO:1904682; GO:1990837 5908 XM_029356394.2 55 39 0 14 0 Q6ZR37 4.43e-84 Pleckstrin homology domain-containing family G member 7 (PH domain-containing family G member 7) Homo sapiens (Human) Rho protein signal transduction [GO:0007266] GO:0005085; GO:0007266 5909 XM_029338369.2 2425 2124 1694 2534 818 Q13591 6.96e-29 Semaphorin-5A (Semaphorin-F) (Sema F) Homo sapiens (Human) axon extension [GO:0048675]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell-cell signaling [GO:0007267]; diencephalon development [GO:0021536]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of cell adhesion [GO:0007162]; negative regulation of endothelial cell apoptotic process [GO:2000352]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; positive chemotaxis [GO:0050918]; positive regulation of actin filament depolymerization [GO:0030836]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein kinase B signaling [GO:0051897]; semaphorin-plexin signaling pathway [GO:0071526]; signal clustering [GO:1990256] GO:0001755; GO:0001938; GO:0002043; GO:0005886; GO:0007155; GO:0007162; GO:0007267; GO:0007399; GO:0007411; GO:0007413; GO:0016020; GO:0021536; GO:0030215; GO:0030335; GO:0030836; GO:0035373; GO:0043395; GO:0045499; GO:0045545; GO:0045766; GO:0048675; GO:0048842; GO:0048843; GO:0050918; GO:0051897; GO:0060326; GO:0070062; GO:0071526; GO:0090263; GO:1990256; GO:2000352; GO:2001028 5910 XM_029356850.2 56 73 75 89 211 NA NA NA NA NA NA 5911 XM_029343303.2 1172 1163 1023 1105 1148 Q9ERM3 8.97e-147 Diacylglycerol O-acyltransferase 1 (EC 2.3.1.20) (Acyl-CoA retinol O-fatty-acyltransferase) (ARAT) (Retinol O-fatty-acyltransferase) (EC 2.3.1.76) (Diglyceride acyltransferase) Rattus norvegicus (Rat) diacylglycerol metabolic process [GO:0046339]; fatty acid homeostasis [GO:0055089]; glycerolipid metabolic process [GO:0046486]; insulin secretion [GO:0030073]; ketone body metabolic process [GO:1902224]; lipid storage [GO:0019915]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]; monoacylglycerol biosynthetic process [GO:0006640]; positive regulation of fatty acid oxidation [GO:0046321]; positive regulation of hepatic stellate cell activation [GO:2000491]; positive regulation of triglyceride biosynthetic process [GO:0010867]; regulation of eating behavior [GO:1903998]; regulation of intestinal lipid absorption [GO:1904729]; regulation of vitamin A metabolic process [GO:1901738]; response to human chorionic gonadotropin [GO:0044752]; triglyceride biosynthetic process [GO:0019432]; very-low-density lipoprotein particle assembly [GO:0034379] GO:0003846; GO:0004144; GO:0005504; GO:0005789; GO:0005886; GO:0006640; GO:0008374; GO:0010867; GO:0016020; GO:0016746; GO:0019432; GO:0019915; GO:0019992; GO:0030073; GO:0034379; GO:0035336; GO:0042802; GO:0043231; GO:0044752; GO:0046321; GO:0046339; GO:0046486; GO:0050252; GO:0055089; GO:1901738; GO:1902224; GO:1903998; GO:1904729; GO:2000491 5912 XR_003824574.2 30 8 41 23 94 NA NA NA NA NA NA 5913 XM_044309088.1 25 0 0 0 0 NA NA NA NA NA NA 5914 XM_029345524.2 6 2 23 11 22 Q8N0W4 2.09e-90 Neuroligin-4, X-linked (Neuroligin X) (HNLX) Homo sapiens (Human) adult behavior [GO:0030534]; brainstem development [GO:0003360]; cell-cell junction organization [GO:0045216]; cerebellum development [GO:0021549]; chemical synaptic transmission [GO:0007268]; learning [GO:0007612]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of excitatory postsynaptic potential [GO:0090394]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; organ growth [GO:0035265]; postsynaptic membrane assembly [GO:0097104]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; social behavior [GO:0035176]; synapse organization [GO:0050808]; synaptic vesicle endocytosis [GO:0048488]; vocalization behavior [GO:0071625] GO:0003360; GO:0005886; GO:0007158; GO:0007268; GO:0007612; GO:0009986; GO:0016020; GO:0021549; GO:0030182; GO:0030425; GO:0030534; GO:0031404; GO:0035176; GO:0035265; GO:0038023; GO:0042043; GO:0042803; GO:0045202; GO:0045216; GO:0048488; GO:0050804; GO:0050808; GO:0050839; GO:0060076; GO:0071625; GO:0090394; GO:0097104; GO:0097105; GO:0097110; GO:0098793; GO:0098839; GO:0098983; GO:0098985; GO:0099054; GO:0099634 5915 XM_029332861.2 0 0 36 241 351 B3DJT0 7.22e-131 Squamous cell carcinoma antigen recognized by T-cells 3 (SART-3) Danio rerio (Zebrafish) (Brachydanio rerio) exocrine pancreas development [GO:0031017]; lymphocyte differentiation [GO:0030098]; mRNA splicing, via spliceosome [GO:0000398]; nucleosome assembly [GO:0006334]; positive regulation of histone deubiquitination [GO:1903586]; spliceosomal complex assembly [GO:0000245]; spliceosomal snRNP assembly [GO:0000387]; thymus development [GO:0048538] GO:0000245; GO:0000387; GO:0000398; GO:0005634; GO:0005654; GO:0005737; GO:0006334; GO:0015030; GO:0016607; GO:0017070; GO:0030098; GO:0031017; GO:0042393; GO:0048538; GO:0061574; GO:1903586 5916 XM_029332861.2 0 0 36 241 351 B3DJT0 1.36e-50 Squamous cell carcinoma antigen recognized by T-cells 3 (SART-3) Danio rerio (Zebrafish) (Brachydanio rerio) exocrine pancreas development [GO:0031017]; lymphocyte differentiation [GO:0030098]; mRNA splicing, via spliceosome [GO:0000398]; nucleosome assembly [GO:0006334]; positive regulation of histone deubiquitination [GO:1903586]; spliceosomal complex assembly [GO:0000245]; spliceosomal snRNP assembly [GO:0000387]; thymus development [GO:0048538] GO:0000245; GO:0000387; GO:0000398; GO:0005634; GO:0005654; GO:0005737; GO:0006334; GO:0015030; GO:0016607; GO:0017070; GO:0030098; GO:0031017; GO:0042393; GO:0048538; GO:0061574; GO:1903586 5917 XM_044326982.1 0 0 6 3 6 NA NA NA NA NA NA 5918 XR_003823951.2 10 0 13 0 48 NA NA NA NA NA NA 5919 XR_006397084.1 69 67 27 25 33 NA NA NA NA NA NA 5920 XR_006393367.1 699 474 371 1171 923 P12820 6.07e-119 Angiotensin-converting enzyme (ACE) (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (CD antigen CD143) [Cleaved into: Angiotensin-converting enzyme, soluble form] Bos taurus (Bovine) amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; arachidonic acid secretion [GO:0050482]; bradykinin catabolic process [GO:0010815]; cell proliferation in bone marrow [GO:0071838]; heart contraction [GO:0060047]; hormone catabolic process [GO:0042447]; hormone metabolic process [GO:0042445]; kidney development [GO:0001822]; male gonad development [GO:0008584]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of gene expression [GO:0010629]; negative regulation of protein binding [GO:0032091]; neutrophil mediated immunity [GO:0002446]; positive regulation of peptidyl-cysteine S-nitrosylation [GO:2000170]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of protein binding [GO:0032092]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of systemic arterial blood pressure [GO:0003084]; post-transcriptional regulation of gene expression [GO:0010608]; regulation of angiotensin metabolic process [GO:0060177]; regulation of blood pressure [GO:0008217]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of synaptic plasticity [GO:0048167]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; spermatogenesis [GO:0007283]; substance P catabolic process [GO:0010814] GO:0001822; GO:0002003; GO:0002446; GO:0003081; GO:0003084; GO:0004180; GO:0004222; GO:0005516; GO:0005764; GO:0005768; GO:0005886; GO:0007283; GO:0008217; GO:0008233; GO:0008237; GO:0008240; GO:0008241; GO:0008270; GO:0008584; GO:0009897; GO:0010608; GO:0010629; GO:0010814; GO:0010815; GO:0031404; GO:0031434; GO:0031711; GO:0032091; GO:0032092; GO:0042445; GO:0042447; GO:0048167; GO:0050435; GO:0050482; GO:0051019; GO:0060047; GO:0060177; GO:0061098; GO:0070062; GO:0070573; GO:0071838; GO:1900086; GO:1902033; GO:1903597; GO:2000170 5921 XR_006393367.1 699 474 371 1171 923 P12820 6.07e-119 Angiotensin-converting enzyme (ACE) (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (CD antigen CD143) [Cleaved into: Angiotensin-converting enzyme, soluble form] Bos taurus (Bovine) amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; arachidonic acid secretion [GO:0050482]; bradykinin catabolic process [GO:0010815]; cell proliferation in bone marrow [GO:0071838]; heart contraction [GO:0060047]; hormone catabolic process [GO:0042447]; hormone metabolic process [GO:0042445]; kidney development [GO:0001822]; male gonad development [GO:0008584]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of gene expression [GO:0010629]; negative regulation of protein binding [GO:0032091]; neutrophil mediated immunity [GO:0002446]; positive regulation of peptidyl-cysteine S-nitrosylation [GO:2000170]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of protein binding [GO:0032092]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of systemic arterial blood pressure [GO:0003084]; post-transcriptional regulation of gene expression [GO:0010608]; regulation of angiotensin metabolic process [GO:0060177]; regulation of blood pressure [GO:0008217]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of synaptic plasticity [GO:0048167]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; spermatogenesis [GO:0007283]; substance P catabolic process [GO:0010814] GO:0001822; GO:0002003; GO:0002446; GO:0003081; GO:0003084; GO:0004180; GO:0004222; GO:0005516; GO:0005764; GO:0005768; GO:0005886; GO:0007283; GO:0008217; GO:0008233; GO:0008237; GO:0008240; GO:0008241; GO:0008270; GO:0008584; GO:0009897; GO:0010608; GO:0010629; GO:0010814; GO:0010815; GO:0031404; GO:0031434; GO:0031711; GO:0032091; GO:0032092; GO:0042445; GO:0042447; GO:0048167; GO:0050435; GO:0050482; GO:0051019; GO:0060047; GO:0060177; GO:0061098; GO:0070062; GO:0070573; GO:0071838; GO:1900086; GO:1902033; GO:1903597; GO:2000170 5922 XR_006393367.1 699 474 371 1171 923 P12820 1.55e-106 Angiotensin-converting enzyme (ACE) (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (CD antigen CD143) [Cleaved into: Angiotensin-converting enzyme, soluble form] Bos taurus (Bovine) amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; arachidonic acid secretion [GO:0050482]; bradykinin catabolic process [GO:0010815]; cell proliferation in bone marrow [GO:0071838]; heart contraction [GO:0060047]; hormone catabolic process [GO:0042447]; hormone metabolic process [GO:0042445]; kidney development [GO:0001822]; male gonad development [GO:0008584]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of gene expression [GO:0010629]; negative regulation of protein binding [GO:0032091]; neutrophil mediated immunity [GO:0002446]; positive regulation of peptidyl-cysteine S-nitrosylation [GO:2000170]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of protein binding [GO:0032092]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of systemic arterial blood pressure [GO:0003084]; post-transcriptional regulation of gene expression [GO:0010608]; regulation of angiotensin metabolic process [GO:0060177]; regulation of blood pressure [GO:0008217]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of synaptic plasticity [GO:0048167]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; spermatogenesis [GO:0007283]; substance P catabolic process [GO:0010814] GO:0001822; GO:0002003; GO:0002446; GO:0003081; GO:0003084; GO:0004180; GO:0004222; GO:0005516; GO:0005764; GO:0005768; GO:0005886; GO:0007283; GO:0008217; GO:0008233; GO:0008237; GO:0008240; GO:0008241; GO:0008270; GO:0008584; GO:0009897; GO:0010608; GO:0010629; GO:0010814; GO:0010815; GO:0031404; GO:0031434; GO:0031711; GO:0032091; GO:0032092; GO:0042445; GO:0042447; GO:0048167; GO:0050435; GO:0050482; GO:0051019; GO:0060047; GO:0060177; GO:0061098; GO:0070062; GO:0070573; GO:0071838; GO:1900086; GO:1902033; GO:1903597; GO:2000170 5923 XR_006393367.1 699 474 371 1171 923 P12820 1.55e-106 Angiotensin-converting enzyme (ACE) (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (CD antigen CD143) [Cleaved into: Angiotensin-converting enzyme, soluble form] Bos taurus (Bovine) amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; arachidonic acid secretion [GO:0050482]; bradykinin catabolic process [GO:0010815]; cell proliferation in bone marrow [GO:0071838]; heart contraction [GO:0060047]; hormone catabolic process [GO:0042447]; hormone metabolic process [GO:0042445]; kidney development [GO:0001822]; male gonad development [GO:0008584]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of gene expression [GO:0010629]; negative regulation of protein binding [GO:0032091]; neutrophil mediated immunity [GO:0002446]; positive regulation of peptidyl-cysteine S-nitrosylation [GO:2000170]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of protein binding [GO:0032092]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of systemic arterial blood pressure [GO:0003084]; post-transcriptional regulation of gene expression [GO:0010608]; regulation of angiotensin metabolic process [GO:0060177]; regulation of blood pressure [GO:0008217]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of synaptic plasticity [GO:0048167]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; spermatogenesis [GO:0007283]; substance P catabolic process [GO:0010814] GO:0001822; GO:0002003; GO:0002446; GO:0003081; GO:0003084; GO:0004180; GO:0004222; GO:0005516; GO:0005764; GO:0005768; GO:0005886; GO:0007283; GO:0008217; GO:0008233; GO:0008237; GO:0008240; GO:0008241; GO:0008270; GO:0008584; GO:0009897; GO:0010608; GO:0010629; GO:0010814; GO:0010815; GO:0031404; GO:0031434; GO:0031711; GO:0032091; GO:0032092; GO:0042445; GO:0042447; GO:0048167; GO:0050435; GO:0050482; GO:0051019; GO:0060047; GO:0060177; GO:0061098; GO:0070062; GO:0070573; GO:0071838; GO:1900086; GO:1902033; GO:1903597; GO:2000170 5924 XM_029355399.2 76 0 133 0 71 A0A1L8HCK2 8.56e-109 Cilia- and flagella-associated protein 298-A (Protein kurly-A) Xenopus laevis (African clawed frog) regulation of cilium movement [GO:0003352] GO:0003352; GO:0005737; GO:0005856; GO:0005929 5925 XM_044323300.1 21 12 0 2 0 Q5R5U3 8.28e-79 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 5926 XM_044323300.1 21 12 0 2 0 Q5R5U3 1.44e-75 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 5927 XM_044323300.1 21 12 0 2 0 Q5R5U3 1.7e-75 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 5928 XM_044323300.1 21 12 0 2 0 Q5R5U3 1.79e-75 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 5929 XM_044323300.1 21 12 0 2 0 Q5R5U3 5.36e-75 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 5930 XM_044323300.1 21 12 0 2 0 Q5R5U3 8.63e-74 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 5931 XM_044323300.1 21 12 0 2 0 Q5R5U3 2.99e-73 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 5932 XM_044323300.1 21 12 0 2 0 Q5R5U3 2.99e-71 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 5933 XM_044323300.1 21 12 0 2 0 Q5R5U3 5.79e-67 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 5934 XM_044323300.1 21 12 0 2 0 Q5R5U3 9.84e-65 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 5935 XM_044321892.1 190 135 39 60 125 NA NA NA NA NA NA 5936 XM_044318337.1 43 2 30 12 42 NA NA NA NA NA NA 5937 XM_029330241.2 401 432 134 492 279 O95163 0 Elongator complex protein 1 (ELP1) (IkappaB kinase complex-associated protein) (IKK complex-associated protein) (p150) Homo sapiens (Human) regulation of translation [GO:0006417]; tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation [GO:0002926]; tRNA wobble uridine modification [GO:0002098] GO:0000049; GO:0002098; GO:0002926; GO:0005634; GO:0005737; GO:0005829; GO:0006417; GO:0033588; GO:0043621 5938 XM_044310328.1 1334 209 269 1114 1515 NA NA NA NA NA NA 5939 XM_044322236.1 0 0 0 0 15 NA NA NA NA NA NA 5940 XM_044312802.1 25 88 37 60 20 Q4KLE6 4.39e-75 N-terminal Xaa-Pro-Lys N-methyltransferase 1-B (EC 2.1.1.244) (Alpha N-terminal protein methyltransferase 1A-B) (Methyltransferase-like protein 11A-B) (X-Pro-Lys N-terminal protein methyltransferase 1A-B) (NTM1A-B) Xenopus laevis (African clawed frog) chromosome segregation [GO:0007059]; histone methylation [GO:0016571]; N-terminal peptidyl-glycine methylation [GO:0018013]; N-terminal peptidyl-proline dimethylation [GO:0018016]; N-terminal peptidyl-serine dimethylation [GO:0035572]; N-terminal peptidyl-serine trimethylation [GO:0035573]; spindle organization [GO:0007051] GO:0005634; GO:0007051; GO:0007059; GO:0008276; GO:0016571; GO:0018013; GO:0018016; GO:0035572; GO:0035573; GO:0042054; GO:0071885 5941 XM_044320464.1 377 0 0 4 0 Q5R606 0 Heat shock protein 105 kDa (Heat shock 110 kDa protein) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0000774; GO:0005524; GO:0005737; GO:0140662 5942 XR_006392041.1 2 1 12 2 23 NA NA NA NA NA NA 5943 XM_029347219.2 0 18 0 8 24 NA NA NA NA NA NA 5944 XR_006394374.1 0 10 0 3 3 NA NA NA NA NA NA 5945 XR_006394796.1 825 722 345 892 705 P51659 0 Peroxisomal multifunctional enzyme type 2 (MFE-2) (17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4) (D-bifunctional protein) (DBP) (Multifunctional protein 2) (MFP-2) (Short chain dehydrogenase/reductase family 8C member 1) [Cleaved into: (3R)-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.n12); Enoyl-CoA hydratase 2 (EC 4.2.1.107) (EC 4.2.1.119) (3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase)] Homo sapiens (Human) androgen metabolic process [GO:0008209]; estrogen metabolic process [GO:0008210]; fatty acid beta-oxidation [GO:0006635]; medium-chain fatty-acyl-CoA metabolic process [GO:0036112]; osteoblast differentiation [GO:0001649]; Sertoli cell development [GO:0060009]; very long-chain fatty acid metabolic process [GO:0000038]; very long-chain fatty-acyl-CoA metabolic process [GO:0036111] GO:0000038; GO:0001649; GO:0003857; GO:0004300; GO:0005777; GO:0005778; GO:0005782; GO:0005829; GO:0006635; GO:0008209; GO:0008210; GO:0016020; GO:0016508; GO:0016853; GO:0033989; GO:0036111; GO:0036112; GO:0042803; GO:0044594; GO:0060009; GO:0106386 5946 XM_044325486.1 0 4 0 27 39 Q96D46 0 60S ribosomal export protein NMD3 (hNMD3) Homo sapiens (Human) positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to nucleolus [GO:1904751]; positive regulation of RNA biosynthetic process [GO:1902680]; protein transport [GO:0015031]; ribosomal large subunit export from nucleus [GO:0000055] GO:0000055; GO:0003723; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0015031; GO:0016020; GO:0030674; GO:0032092; GO:0043023; GO:1902680; GO:1904751 5947 XM_029337238.2 106 202 37 219 76 P62246 1.01e-78 40S ribosomal protein S15a Rattus norvegicus (Rat) positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; response to virus [GO:0009615]; translation [GO:0006412] GO:0003735; GO:0005737; GO:0006412; GO:0008284; GO:0009615; GO:0022626; GO:0022627; GO:0045202; GO:0045787 5948 XR_006395264.1 32 18 33 74 72 Q5RK27 5.66e-140 Solute carrier family 12 member 7 (Electroneutral potassium-chloride cotransporter 4) (K-Cl cotransporter 4) Rattus norvegicus (Rat) ammonium import across plasma membrane [GO:0140157]; cell volume homeostasis [GO:0006884]; cellular response to glucose stimulus [GO:0071333]; chemical synaptic transmission [GO:0007268]; chloride ion homeostasis [GO:0055064]; chloride transmembrane transport [GO:1902476]; potassium ion homeostasis [GO:0055075]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805] GO:0005886; GO:0006884; GO:0007268; GO:0008519; GO:0015379; GO:0019901; GO:0032991; GO:0045202; GO:0055064; GO:0055075; GO:0071333; GO:0071805; GO:0140157; GO:1902476; GO:1990573 5949 XR_006395264.1 32 18 33 74 72 Q5RK27 5.66e-140 Solute carrier family 12 member 7 (Electroneutral potassium-chloride cotransporter 4) (K-Cl cotransporter 4) Rattus norvegicus (Rat) ammonium import across plasma membrane [GO:0140157]; cell volume homeostasis [GO:0006884]; cellular response to glucose stimulus [GO:0071333]; chemical synaptic transmission [GO:0007268]; chloride ion homeostasis [GO:0055064]; chloride transmembrane transport [GO:1902476]; potassium ion homeostasis [GO:0055075]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805] GO:0005886; GO:0006884; GO:0007268; GO:0008519; GO:0015379; GO:0019901; GO:0032991; GO:0045202; GO:0055064; GO:0055075; GO:0071333; GO:0071805; GO:0140157; GO:1902476; GO:1990573 5950 XM_044328565.1 0 1 30 9 41 NA NA NA NA NA NA 5951 XM_029337658.2 0 88 0 0 0 Q5YCC5 8.49e-87 Transmembrane channel-like protein 7 Gallus gallus (Chicken) NA GO:0005886; GO:0008381 5952 XM_029333350.2 2058 1077 549 400 1373 Q26614 5.65e-140 Fibroblast growth factor receptor (SpFGFR) (EC 2.7.10.1) Strongylocentrotus purpuratus (Purple sea urchin) positive regulation of kinase activity [GO:0033674]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0004714; GO:0005007; GO:0005524; GO:0005886; GO:0007169; GO:0017134; GO:0033674; GO:0043235 5953 XM_044320122.1 17 50 1 86 35 NA NA NA NA NA NA 5954 XM_044308250.1 1356 858 739 1492 1220 Q86YW9 2.38e-104 Mediator of RNA polymerase II transcription subunit 12-like protein (Mediator complex subunit 12-like protein) (Thyroid hormone receptor-associated-like protein) (Trinucleotide repeat-containing gene 11 protein-like) Homo sapiens (Human) positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0003713; GO:0008013; GO:0016592; GO:0045944 5955 XR_003827187.2 64 212 48 150 68 NA NA NA NA NA NA 5956 XM_029328544.2 654 598 410 630 815 Q99P25 1.4e-129 Translin-associated factor X-interacting protein 1 (Trax-interacting protein 1) Mus musculus (Mouse) cell differentiation [GO:0030154]; spermatogenesis [GO:0007283] GO:0005737; GO:0007283; GO:0030154; GO:0048471 5957 XM_029330876.2 1 0 2 0 18 NA NA NA NA NA NA 5958 XM_044313556.1 0 0 22 9 0 Q8NFF2 7.05e-116 Sodium/potassium/calcium exchanger 4 (Na(+)/K(+)/Ca(2+)-exchange protein 4) (Solute carrier family 24 member 4) Homo sapiens (Human) amelogenesis [GO:0097186]; calcium ion export across plasma membrane [GO:1990034]; calcium ion homeostasis [GO:0055074]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; cellular response to high light intensity [GO:0071486]; cone photoresponse recovery [GO:0036368]; detection of chemical stimulus involved in sensory perception of smell [GO:0050911]; drinking behavior [GO:0042756]; enamel mineralization [GO:0070166]; ion transport [GO:0006811]; membrane repolarization [GO:0086009]; negative regulation of calcium-mediated signaling [GO:0050849]; olfactory nerve maturation [GO:0021630]; phototransduction [GO:0007602]; positive regulation of gene expression [GO:0010628]; potassium ion transmembrane transport [GO:0071805]; regulation of eating behavior [GO:1903998]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; regulation of signaling receptor activity [GO:0010469]; response to high light intensity [GO:0009644]; response to melanocyte-stimulating hormone [GO:1990680]; response to odorant [GO:1990834]; sensory perception of smell [GO:0007608]; sodium ion transmembrane transport [GO:0035725] GO:0005262; GO:0005516; GO:0005737; GO:0005886; GO:0006811; GO:0006874; GO:0007602; GO:0007608; GO:0008273; GO:0008277; GO:0009644; GO:0010469; GO:0010628; GO:0015293; GO:0016020; GO:0016324; GO:0021630; GO:0031982; GO:0035725; GO:0036368; GO:0042756; GO:0048306; GO:0050849; GO:0050911; GO:0055074; GO:0070166; GO:0070588; GO:0071486; GO:0071805; GO:0086009; GO:0097186; GO:0098703; GO:0120199; GO:1903998; GO:1990034; GO:1990680; GO:1990834 5959 XM_029339712.2 877 499 300 541 352 Q0VFN8 2.8e-109 Cilia- and flagella-associated protein 157 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) sperm axoneme assembly [GO:0007288] GO:0005737; GO:0007288; GO:0008017; GO:0036064 5960 XR_006395201.1 64 107 43 79 50 NA NA NA NA NA NA 5961 XM_029328876.2 251 209 333 203 173 NA NA NA NA NA NA 5962 XM_029329218.2 0 0 0 0 36 NA NA NA NA NA NA 5963 XM_044309640.1 204 272 50 166 173 NA NA NA NA NA NA 5964 XM_044312117.1 1249 871 838 1458 1384 Q4ZIN3 1.51e-157 Membralin (Transmembrane protein 259) Homo sapiens (Human) negative regulation of neuron death [GO:1901215]; positive regulation of ERAD pathway [GO:1904294]; response to endoplasmic reticulum stress [GO:0034976] GO:0005783; GO:0005789; GO:0034976; GO:1901215; GO:1904294 5965 XM_029356903.2 352 232 146 436 302 Q969K4 2.89e-141 Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein) Homo sapiens (Human) NA GO:0000151; GO:0003746; GO:0005730; GO:0005737; GO:0005829; GO:0005886 5966 XR_006396357.1 14 2 9 11 17 NA NA NA NA NA NA 5967 XM_044314735.1 0 20 27 0 35 NA NA NA NA NA NA 5968 XM_044308075.1 47 17 0 22 51 Q6P4F7 1.51e-32 Rho GTPase-activating protein 11A (Rho-type GTPase-activating protein 11A) Homo sapiens (Human) positive regulation of GTPase activity [GO:0043547]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] GO:0005096; GO:0005634; GO:0005829; GO:0007165; GO:0043547; GO:0051056 5969 XM_029351990.2 263 88 635 120 1039 P18907 0 Sodium/potassium-transporting ATPase subunit alpha-1 (Sodium pump subunit alpha-1) (EC 7.2.2.13) (Na(+)/K(+) ATPase alpha-1 subunit) Equus caballus (Horse) cellular potassium ion homeostasis [GO:0030007]; cellular sodium ion homeostasis [GO:0006883]; potassium ion import across plasma membrane [GO:1990573]; proton transmembrane transport [GO:1902600]; regulation of sodium ion transport [GO:0002028]; sodium ion export across plasma membrane [GO:0036376] GO:0002028; GO:0005391; GO:0005524; GO:0005886; GO:0005890; GO:0006883; GO:0016020; GO:0016323; GO:0016887; GO:0019829; GO:0030007; GO:0030424; GO:0036376; GO:0042383; GO:0042470; GO:0046872; GO:1902600; GO:1990573 5970 XR_006396202.1 53 155 32 141 177 NA NA NA NA NA NA 5971 XM_044328628.1 6681 2312 2122 5354 2578 P54145 2.69e-86 Putative ammonium transporter 1 Caenorhabditis elegans ammonium homeostasis [GO:0097272]; ammonium transmembrane transport [GO:0072488] GO:0005886; GO:0008519; GO:0072488; GO:0097272 5972 XM_044314591.1 0 0 1 0 12 P35067 1.8e-82 Histone H2B Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 5973 XM_044321416.1 75 106 94 104 294 Q2M389 1.94e-26 WASH complex subunit 4 (Strumpellin and WASH-interacting protein) (SWIP) (WASH complex subunit SWIP) Homo sapiens (Human) endosomal transport [GO:0016197]; endosome organization [GO:0007032]; nuclear envelope budding [GO:0140591]; protein transport [GO:0015031]; regulation of Arp2/3 complex-mediated actin nucleation [GO:0034315] GO:0005654; GO:0005768; GO:0007032; GO:0015031; GO:0016197; GO:0031901; GO:0034315; GO:0071203; GO:0140591 5974 XM_029347890.2 33 142 100 133 195 NA NA NA NA NA NA 5975 XM_044316627.1 28 0 0 0 0 Q8RWL6 5.57e-29 Serine/threonine-protein kinase STY17 (EC 2.7.11.1) (Serine/threonine/tyrosine-protein kinase 17) Arabidopsis thaliana (Mouse-ear cress) chloroplast organization [GO:0009658]; protein phosphorylation [GO:0006468] GO:0004674; GO:0004712; GO:0005524; GO:0005829; GO:0006468; GO:0009658; GO:0106310 5976 XM_044316627.1 28 0 0 0 0 Q8RWL6 8.12e-29 Serine/threonine-protein kinase STY17 (EC 2.7.11.1) (Serine/threonine/tyrosine-protein kinase 17) Arabidopsis thaliana (Mouse-ear cress) chloroplast organization [GO:0009658]; protein phosphorylation [GO:0006468] GO:0004674; GO:0004712; GO:0005524; GO:0005829; GO:0006468; GO:0009658; GO:0106310 5977 XM_029357337.2 0 23 0 0 58 P22770 9.61e-72 Neuronal acetylcholine receptor subunit alpha-7 Gallus gallus (Chicken) calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; cognition [GO:0050890]; membrane depolarization [GO:0051899]; negative regulation of tumor necrosis factor production [GO:0032720]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAPK cascade [GO:0043410]; regulation of nitric oxide metabolic process [GO:0080164]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; signal transduction [GO:0007165] GO:0001540; GO:0001666; GO:0005737; GO:0005886; GO:0005892; GO:0006816; GO:0006874; GO:0007165; GO:0008284; GO:0015464; GO:0015643; GO:0017081; GO:0022848; GO:0030424; GO:0030425; GO:0032720; GO:0035094; GO:0042166; GO:0042803; GO:0043204; GO:0043410; GO:0045211; GO:0045766; GO:0050890; GO:0051899; GO:0080164 5978 XM_044328937.1 35 38 9 0 11 NA NA NA NA NA NA 5979 XM_044322910.1 0 194 0 0 0 Q8N2E2 1.32e-39 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 5980 XM_044322910.1 0 194 0 0 0 Q8N2E2 8.08e-38 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 5981 XM_044322910.1 0 194 0 0 0 Q8N2E2 1.44e-36 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 5982 XM_044322910.1 0 194 0 0 0 Q8N2E2 4.54e-35 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 5983 XM_044322910.1 0 194 0 0 0 Q8N2E2 5.4e-32 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 5984 XM_044322910.1 0 194 0 0 0 Q8N2E2 4.02e-25 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 5985 XM_044327709.1 52 28 34 42 99 NA NA NA NA NA NA 5986 XM_029339914.2 804 1262 1246 1434 1336 Q6P268 3.18e-82 Phosducin-like protein 3 (Viral IAP-associated factor 1 homolog) Danio rerio (Zebrafish) (Brachydanio rerio) angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; positive regulation of gene expression [GO:0010628]; protein folding [GO:0006457] GO:0001525; GO:0005737; GO:0005783; GO:0006457; GO:0006915; GO:0010628; GO:0043184; GO:0044183; GO:0048471 5987 XM_029325378.2 236 298 308 285 393 Q4KLA0 3.34e-124 Cyclin-C Xenopus laevis (African clawed frog) regulation of transcription by RNA polymerase II [GO:0006357] GO:0005634; GO:0006357; GO:0016538 5988 XR_006395087.1 53 46 57 91 115 NA NA NA NA NA NA 5989 XM_044317283.1 135 259 151 263 296 Q9Y394 2.46e-72 Dehydrogenase/reductase SDR family member 7 (EC 1.1.1.-) (Retinal short-chain dehydrogenase/reductase 4) (retSDR4) (Short chain dehydrogenase/reductase family 34C member 1) (Protein SDR34C1) Homo sapiens (Human) NA GO:0004090; GO:0005789; GO:0016020; GO:0016616; GO:0052650 5990 XM_029334103.2 643 490 301 335 334 Q96QU6 2.17e-84 1-aminocyclopropane-1-carboxylate synthase-like protein 1 (ACC synthase-like protein 1) Homo sapiens (Human) amino acid metabolic process [GO:0006520]; biosynthetic process [GO:0009058] GO:0006520; GO:0008483; GO:0009058; GO:0030170; GO:0042802 5991 XR_006398019.1 32 26 26 28 35 NA NA NA NA NA NA 5992 XM_029354644.2 134 64 83 190 129 E7FAM5 7.3e-48 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 5993 XM_044325803.1 16 0 0 0 12 Q80XJ3 1.96e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 5994 XM_044325803.1 16 0 0 0 12 Q80XJ3 9.37e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 5995 XM_044325803.1 16 0 0 0 12 Q80XJ3 1.33e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 5996 XM_044325803.1 16 0 0 0 12 Q80XJ3 3.8e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 5997 XM_044325803.1 16 0 0 0 12 Q80XJ3 8.42e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 5998 XM_044325803.1 16 0 0 0 12 Q80XJ3 5.47e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 5999 XM_044325803.1 16 0 0 0 12 Q80XJ3 1.78e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 6000 XM_044325803.1 16 0 0 0 12 Q80XJ3 1.99e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 6001 XM_044325803.1 16 0 0 0 12 Q80XJ3 6.18e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 6002 XM_044325803.1 16 0 0 0 12 Q80XJ3 5.87e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 6003 XM_044325803.1 16 0 0 0 12 Q80XJ3 9.97e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 6004 XM_044325803.1 16 0 0 0 12 Q80XJ3 1.46e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 6005 XM_044325803.1 16 0 0 0 12 Q80XJ3 2.62e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 6006 XM_044325803.1 16 0 0 0 12 Q80XJ3 8.02e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 6007 XM_044319347.1 1913 697 1016 1856 1810 Q9H5I5 2.34e-147 Piezo-type mechanosensitive ion channel component 2 (Protein FAM38B) Homo sapiens (Human) cation transport [GO:0006812]; cellular response to mechanical stimulus [GO:0071260]; detection of mechanical stimulus [GO:0050982]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; regulation of membrane potential [GO:0042391]; response to mechanical stimulus [GO:0009612] GO:0005261; GO:0005886; GO:0006812; GO:0008381; GO:0009612; GO:0016020; GO:0042391; GO:0050974; GO:0050982; GO:0071260 6008 XM_044319347.1 1913 697 1016 1856 1810 Q9H5I5 4.62e-123 Piezo-type mechanosensitive ion channel component 2 (Protein FAM38B) Homo sapiens (Human) cation transport [GO:0006812]; cellular response to mechanical stimulus [GO:0071260]; detection of mechanical stimulus [GO:0050982]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; regulation of membrane potential [GO:0042391]; response to mechanical stimulus [GO:0009612] GO:0005261; GO:0005886; GO:0006812; GO:0008381; GO:0009612; GO:0016020; GO:0042391; GO:0050974; GO:0050982; GO:0071260 6009 XM_044326930.1 32 2 20 5 85 NA NA NA NA NA NA 6010 XM_044312293.1 5 12 1 0 5 NA NA NA NA NA NA 6011 XM_029334490.2 27 7 6 5 3 O13018 2.29e-44 Vertebrate ancient opsin Salmo salar (Atlantic salmon) phototransduction, visible light [GO:0007603] GO:0004930; GO:0007603; GO:0009881; GO:0016020 6012 XR_006392597.1 116 136 26 25 23 NA NA NA NA NA NA 6013 XM_029346371.2 900 652 616 900 1429 Q6P6Z0 0 DNA damage-binding protein 1 (Damage-specific DNA-binding protein 1) Xenopus laevis (African clawed frog) DNA repair [GO:0006281]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511] GO:0003677; GO:0005634; GO:0005737; GO:0006281; GO:0016567; GO:0031464; GO:0031465; GO:0042752; GO:0043161; GO:0048511; GO:0080008 6014 XM_044321954.1 26 6 57 13 0 NA NA NA NA NA NA 6015 XM_044307791.1 0 0 0 0 31 Q0VFM0 2.83e-82 Zinc finger protein-like 1 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) vesicle-mediated transport [GO:0016192] GO:0005794; GO:0016020; GO:0016192; GO:0046872 6016 XM_029345878.2 148 62 70 49 54 NA NA NA NA NA NA 6017 XM_029354004.2 3 4 2 2 21 NA NA NA NA NA NA 6018 XM_044319149.1 85 33 0 20 151 P0DX22 1.36e-51 NA NA NA NA 6019 XM_044324595.1 35 8 8 5 70 NA NA NA NA NA NA 6020 XM_044329062.1 70 27 133 55 114 O60290 7.22e-47 Zinc finger protein 862 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006355; GO:0046872; GO:0046983 6021 XM_044319265.1 743 852 376 446 465 Q9NQQ7 9.68e-67 Solute carrier family 35 member C2 (Ovarian cancer-overexpressed gene 1 protein) Homo sapiens (Human) negative regulation of gene expression [GO:0010629]; positive regulation of Notch signaling pathway [GO:0045747]; protein O-linked fucosylation [GO:0036066]; UDP-glucose transmembrane transport [GO:0015786] GO:0005654; GO:0005793; GO:0005794; GO:0005801; GO:0010629; GO:0015297; GO:0015786; GO:0033116; GO:0036066; GO:0045747 6022 XM_029344779.2 58 5 11 46 84 Q6GLB9 1.78e-24 Homeobox protein EMX1 (Empty spiracles homolog 1) (Empty spiracles-like protein 1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0000981; GO:0003677; GO:0005634 6023 XM_044306762.1 116 104 31 76 207 P30884 1.04e-75 Bone morphogenetic protein 2-B (BMP-2-II) Xenopus laevis (African clawed frog) cartilage development [GO:0051216]; cell differentiation [GO:0030154]; ossification [GO:0001503] GO:0001503; GO:0005125; GO:0005615; GO:0008083; GO:0030154; GO:0051216 6024 XR_003827055.2 14 7 8 2 36 NA NA NA NA NA NA 6025 XM_029323669.2 208 422 206 480 405 NA NA NA NA NA NA 6026 XM_029335635.2 15 294 59 244 256 Q8BKD6 2.55e-64 E3 ubiquitin-protein ligase RNF144B (EC 2.3.2.31) (IBR domain-containing protein 2) (RING finger protein 144B) Mus musculus (Mouse) apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000151; GO:0000209; GO:0004842; GO:0005737; GO:0006511; GO:0006915; GO:0031624; GO:0031966; GO:0032436; GO:0043066; GO:0046872; GO:0061630 6027 XM_044307906.1 12 24 23 4 67 NA NA NA NA NA NA 6028 XM_029352042.2 45 0 0 0 0 A7SDW5 0 Eukaryotic translation initiation factor 3 subunit L (eIF3l) Nematostella vectensis (Starlet sea anemone) formation of cytoplasmic translation initiation complex [GO:0001732]; translational initiation [GO:0006413] GO:0001732; GO:0003743; GO:0005852; GO:0006413; GO:0016282; GO:0033290 6029 XM_044315903.1 0 29 12 20 27 NA NA NA NA NA NA 6030 XM_044328223.1 9 0 9 10 15 Q09575 7.33e-33 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 6031 XM_029356117.2 26 8 35 33 70 Q924H0 1.58e-32 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide NPFF receptor) Mus musculus (Mouse) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 6032 XM_029331688.2 57 51 37 54 13 NA NA NA NA NA NA 6033 XM_029352262.2 439 338 187 519 259 NA NA NA NA NA NA 6034 XM_029343306.2 0 86 0 61 0 Q9D0R9 4.02e-36 WD repeat-containing protein 89 Mus musculus (Mouse) corpus callosum development [GO:0022038]; ventricular system development [GO:0021591] GO:0021591; GO:0022038 6035 XM_029356797.2 12 12 10 30 22 Q99542 4.31e-53 Matrix metalloproteinase-19 (MMP-19) (EC 3.4.24.-) (Matrix metalloproteinase RASI) (Matrix metalloproteinase-18) (MMP-18) Homo sapiens (Human) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; luteolysis [GO:0001554]; ovarian follicle development [GO:0001541]; ovulation from ovarian follicle [GO:0001542]; proteolysis [GO:0006508]; response to cAMP [GO:0051591]; response to hormone [GO:0009725] GO:0001525; GO:0001541; GO:0001542; GO:0001554; GO:0004222; GO:0004252; GO:0005576; GO:0005615; GO:0006508; GO:0008270; GO:0009725; GO:0022617; GO:0030154; GO:0030198; GO:0030574; GO:0031012; GO:0051591 6036 XM_044310638.1 12 1 9 0 36 NA NA NA NA NA NA 6037 XM_044315329.1 317 184 261 492 344 NA NA NA NA NA NA 6038 XR_003826231.2 234 155 223 252 247 NA NA NA NA NA NA 6039 XM_044309840.1 2 0 12 5 7 NA NA NA NA NA NA 6040 XM_044311352.1 41 7 0 5 4 Q9H5F2 3.18e-34 Uncharacterized protein CFAP68 (cilia and flagella associated protein 68) Homo sapiens (Human) NA GO:0005654 6041 XR_006398162.1 27 0 3 5 16 NA NA NA NA NA NA 6042 XM_044310579.1 10 0 6 0 9 NA NA NA NA NA NA 6043 XR_003828546.2 11 0 0 68 0 NA NA NA NA NA NA 6044 XR_006392440.1 35 17 84 53 27 NA NA NA NA NA NA 6045 XM_029346297.2 101 94 57 163 25 Q9DCG9 2.47e-35 Multifunctional methyltransferase subunit TRM112-like protein (tRNA methyltransferase 112 homolog) Mus musculus (Mouse) histone lysine methylation [GO:0034968]; peptidyl-glutamine methylation [GO:0018364]; positive regulation of rRNA processing [GO:2000234]; rRNA (guanine-N7)-methylation [GO:0070476]; rRNA methylation [GO:0031167]; tRNA methylation [GO:0030488]; tRNA N2-guanine methylation [GO:0002940] GO:0002940; GO:0005654; GO:0008276; GO:0018364; GO:0030488; GO:0031167; GO:0032991; GO:0034968; GO:0046982; GO:0048471; GO:0070476; GO:2000234 6046 XM_044323550.1 406 464 255 301 287 Q5REG4 5.49e-53 Probable E3 ubiquitin-protein ligase DTX3 (EC 2.3.2.27) (Protein deltex-3) (Deltex3) (RING-type E3 ubiquitin transferase DTX3) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) Notch signaling pathway [GO:0007219]; protein ubiquitination [GO:0016567] GO:0005737; GO:0007219; GO:0016567; GO:0016740; GO:0046872 6047 XM_029346204.2 36 9 6 79 0 NA NA NA NA NA NA 6048 XR_006394356.1 0 0 0 0 6 NA NA NA NA NA NA 6049 XM_029333964.2 486 52 37 677 148 NA NA NA NA NA NA 6050 XM_044325025.1 8 0 0 0 0 NA NA NA NA NA NA 6051 XR_006391493.1 1 54 0 0 12 NA NA NA NA NA NA 6052 XM_044321852.1 563 411 397 549 424 P50747 4.67e-113 Biotin--protein ligase (EC 6.3.4.-) (Biotin apo-protein ligase) [Includes: Biotin--[methylmalonyl-CoA-carboxytransferase] ligase (EC 6.3.4.9); Biotin--[propionyl-CoA-carboxylase [ATP-hydrolyzing]] ligase (EC 6.3.4.10) (Holocarboxylase synthetase) (HCS); Biotin--[methylcrotonoyl-CoA-carboxylase] ligase (EC 6.3.4.11); Biotin--[acetyl-CoA-carboxylase] ligase (EC 6.3.4.15)] Homo sapiens (Human) biotin metabolic process [GO:0006768]; post-translational protein modification [GO:0043687]; response to biotin [GO:0070781] GO:0000785; GO:0004077; GO:0004078; GO:0004079; GO:0004080; GO:0005524; GO:0005652; GO:0005737; GO:0005739; GO:0005829; GO:0006768; GO:0009374; GO:0016363; GO:0018271; GO:0019899; GO:0043687; GO:0070781 6053 XM_044328290.1 3252 3584 2692 6046 6022 P17844 0 Probable ATP-dependent RNA helicase DDX5 (EC 3.6.4.13) (DEAD box protein 5) (RNA helicase p68) Homo sapiens (Human) alternative mRNA splicing, via spliceosome [GO:0000380]; androgen receptor signaling pathway [GO:0030521]; BMP signaling pathway [GO:0030509]; epithelial to mesenchymal transition [GO:0001837]; intracellular estrogen receptor signaling pathway [GO:0030520]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; miRNA transcription [GO:0061614]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transcription [GO:0009299]; myoblast differentiation [GO:0045445]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nuclear-transcribed mRNA catabolic process [GO:0000956]; positive regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043517]; primary miRNA processing [GO:0031053]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of osteoblast differentiation [GO:0045667]; regulation of skeletal muscle cell differentiation [GO:2001014]; regulation of transcription by RNA polymerase II [GO:0006357]; rhythmic process [GO:0048511] GO:0000122; GO:0000380; GO:0000381; GO:0000398; GO:0000956; GO:0001837; GO:0003723; GO:0003724; GO:0003730; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005829; GO:0006357; GO:0009299; GO:0016020; GO:0016607; GO:0016887; GO:0030509; GO:0030520; GO:0030521; GO:0031053; GO:0035500; GO:0036002; GO:0043021; GO:0043517; GO:0045445; GO:0045667; GO:0046332; GO:0048511; GO:0050681; GO:0060765; GO:0061614; GO:0070062; GO:0070412; GO:0070878; GO:0071013; GO:0072332; GO:1990841; GO:1990904; GO:2001014 6054 XR_003825553.2 66 4 156 139 23 NA NA NA NA NA NA 6055 XM_044321321.1 0 0 36 126 37 Q13416 1.09e-112 Origin recognition complex subunit 2 Homo sapiens (Human) DNA replication initiation [GO:0006270]; negative regulation of transcription by RNA polymerase II [GO:0000122] GO:0000122; GO:0000781; GO:0000792; GO:0000808; GO:0000939; GO:0003688; GO:0005634; GO:0005654; GO:0005664; GO:0005813; GO:0006270; GO:0016020 6056 XR_006397018.1 73 40 64 41 90 NA NA NA NA NA NA 6057 XM_044307920.1 0 10 0 19 3 NA NA NA NA NA NA 6058 XM_044328715.1 70 79 70 99 63 NA NA NA NA NA NA 6059 XM_044325878.1 0 17 22 0 0 NA NA NA NA NA NA 6060 XM_029335584.2 2277 1378 1148 1872 2132 P34152 0 Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK) Mus musculus (Mouse) angiogenesis [GO:0001525]; axonogenesis [GO:0007409]; blood vessel development [GO:0001568]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular chloride ion homeostasis [GO:0030644]; cellular response to transforming growth factor beta stimulus [GO:0071560]; central nervous system neuron axonogenesis [GO:0021955]; endothelial cell migration [GO:0043542]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; extracellular matrix organization [GO:0030198]; growth hormone receptor signaling pathway [GO:0060396]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; JNK cascade [GO:0007254]; MAPK cascade [GO:0000165]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of organ growth [GO:0046621]; negative regulation of synapse assembly [GO:0051964]; neuron migration [GO:0001764]; nuclear migration [GO:0007097]; organ growth [GO:0035265]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of macrophage proliferation [GO:0120041]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of wound healing [GO:0090303]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell adhesion [GO:0030155]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of epithelial cell migration [GO:0010632]; regulation of focal adhesion assembly [GO:0051893]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of osteoblast differentiation [GO:0045667]; regulation of protein phosphorylation [GO:0001932]; regulation of substrate adhesion-dependent cell spreading [GO:1900024]; signal complex assembly [GO:0007172]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]; vasodilation [GO:0042311] GO:0000165; GO:0000226; GO:0001525; GO:0001568; GO:0001570; GO:0001725; GO:0001764; GO:0001932; GO:0001934; GO:0003779; GO:0004713; GO:0004715; GO:0004725; GO:0005102; GO:0005178; GO:0005524; GO:0005634; GO:0005730; GO:0005737; GO:0005829; GO:0005886; GO:0005925; GO:0005938; GO:0006468; GO:0007097; GO:0007169; GO:0007172; GO:0007173; GO:0007179; GO:0007229; GO:0007254; GO:0007409; GO:0008284; GO:0008360; GO:0008432; GO:0010507; GO:0010613; GO:0010632; GO:0010634; GO:0010718; GO:0010759; GO:0010763; GO:0014068; GO:0014704; GO:0014911; GO:0016323; GO:0016324; GO:0016477; GO:0016604; GO:0018108; GO:0019901; GO:0019902; GO:0019903; GO:0021955; GO:0022408; GO:0030027; GO:0030154; GO:0030155; GO:0030198; GO:0030307; GO:0030335; GO:0030336; GO:0030644; GO:0031234; GO:0033628; GO:0035265; GO:0036064; GO:0038083; GO:0042127; GO:0042169; GO:0042311; GO:0042383; GO:0042802; GO:0043066; GO:0043197; GO:0043231; GO:0043542; GO:0043548; GO:0044877; GO:0045087; GO:0045202; GO:0045667; GO:0045785; GO:0045860; GO:0046621; GO:0046777; GO:0048013; GO:0048471; GO:0048661; GO:0050766; GO:0050771; GO:0050806; GO:0051893; GO:0051897; GO:0051964; GO:0060252; GO:0060396; GO:0071560; GO:0090303; GO:0098794; GO:0098978; GO:0120041; GO:0140677; GO:1900024; GO:1905274; GO:2000060; GO:2000811 6061 XM_029335584.2 2277 1378 1148 1872 2132 P34152 7.47e-29 Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK) Mus musculus (Mouse) angiogenesis [GO:0001525]; axonogenesis [GO:0007409]; blood vessel development [GO:0001568]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular chloride ion homeostasis [GO:0030644]; cellular response to transforming growth factor beta stimulus [GO:0071560]; central nervous system neuron axonogenesis [GO:0021955]; endothelial cell migration [GO:0043542]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; extracellular matrix organization [GO:0030198]; growth hormone receptor signaling pathway [GO:0060396]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; JNK cascade [GO:0007254]; MAPK cascade [GO:0000165]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of organ growth [GO:0046621]; negative regulation of synapse assembly [GO:0051964]; neuron migration [GO:0001764]; nuclear migration [GO:0007097]; organ growth [GO:0035265]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of macrophage proliferation [GO:0120041]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of wound healing [GO:0090303]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell adhesion [GO:0030155]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of epithelial cell migration [GO:0010632]; regulation of focal adhesion assembly [GO:0051893]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of osteoblast differentiation [GO:0045667]; regulation of protein phosphorylation [GO:0001932]; regulation of substrate adhesion-dependent cell spreading [GO:1900024]; signal complex assembly [GO:0007172]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]; vasodilation [GO:0042311] GO:0000165; GO:0000226; GO:0001525; GO:0001568; GO:0001570; GO:0001725; GO:0001764; GO:0001932; GO:0001934; GO:0003779; GO:0004713; GO:0004715; GO:0004725; GO:0005102; GO:0005178; GO:0005524; GO:0005634; GO:0005730; GO:0005737; GO:0005829; GO:0005886; GO:0005925; GO:0005938; GO:0006468; GO:0007097; GO:0007169; GO:0007172; GO:0007173; GO:0007179; GO:0007229; GO:0007254; GO:0007409; GO:0008284; GO:0008360; GO:0008432; GO:0010507; GO:0010613; GO:0010632; GO:0010634; GO:0010718; GO:0010759; GO:0010763; GO:0014068; GO:0014704; GO:0014911; GO:0016323; GO:0016324; GO:0016477; GO:0016604; GO:0018108; GO:0019901; GO:0019902; GO:0019903; GO:0021955; GO:0022408; GO:0030027; GO:0030154; GO:0030155; GO:0030198; GO:0030307; GO:0030335; GO:0030336; GO:0030644; GO:0031234; GO:0033628; GO:0035265; GO:0036064; GO:0038083; GO:0042127; GO:0042169; GO:0042311; GO:0042383; GO:0042802; GO:0043066; GO:0043197; GO:0043231; GO:0043542; GO:0043548; GO:0044877; GO:0045087; GO:0045202; GO:0045667; GO:0045785; GO:0045860; GO:0046621; GO:0046777; GO:0048013; GO:0048471; GO:0048661; GO:0050766; GO:0050771; GO:0050806; GO:0051893; GO:0051897; GO:0051964; GO:0060252; GO:0060396; GO:0071560; GO:0090303; GO:0098794; GO:0098978; GO:0120041; GO:0140677; GO:1900024; GO:1905274; GO:2000060; GO:2000811 6062 XM_029339871.2 25 7 14 15 181 NA NA NA NA NA NA 6063 XM_044326197.1 10 3 10 15 21 NA NA NA NA NA NA 6064 XM_029339518.2 192 256 156 164 162 NA NA NA NA NA NA 6065 XR_003823695.2 80 8 8 8 73 NA NA NA NA NA NA 6066 XM_029344018.2 6993 13063 6265 11378 8844 NA NA NA NA NA NA 6067 XM_029343368.2 33 0 37 15 0 NA NA NA NA NA NA 6068 XM_044318994.1 113 191 110 64 72 B5DF45 3.8e-108 TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6) Rattus norvegicus (Rat) activation of NF-kappaB-inducing kinase activity [GO:0007250]; activation of protein kinase activity [GO:0032147]; animal organ morphogenesis [GO:0009887]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; bone remodeling [GO:0046849]; bone resorption [GO:0045453]; cell development [GO:0048468]; cellular response to cytokine stimulus [GO:0071345]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-17-mediated signaling pathway [GO:0097400]; JNK cascade [GO:0007254]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin production [GO:0002637]; response to interleukin-1 [GO:0070555]; response to ischemia [GO:0002931]; signal transduction [GO:0007165]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000122; GO:0000209; GO:0001503; GO:0001701; GO:0001843; GO:0002637; GO:0002726; GO:0002931; GO:0004842; GO:0005164; GO:0005634; GO:0005737; GO:0005811; GO:0005829; GO:0005886; GO:0005938; GO:0006955; GO:0006974; GO:0007165; GO:0007249; GO:0007250; GO:0007254; GO:0008270; GO:0009887; GO:0009898; GO:0016567; GO:0019221; GO:0019886; GO:0019901; GO:0030316; GO:0031435; GO:0031624; GO:0031625; GO:0031666; GO:0031996; GO:0032147; GO:0032735; GO:0032743; GO:0032755; GO:0032813; GO:0032991; GO:0033209; GO:0035631; GO:0042088; GO:0042102; GO:0042475; GO:0042802; GO:0042826; GO:0042981; GO:0043011; GO:0043122; GO:0043123; GO:0043422; GO:0043507; GO:0045453; GO:0045672; GO:0045892; GO:0045944; GO:0046330; GO:0046849; GO:0047485; GO:0048468; GO:0048471; GO:0048661; GO:0050852; GO:0051091; GO:0051092; GO:0051865; GO:0061630; GO:0070498; GO:0070534; GO:0070555; GO:0071222; GO:0071345; GO:0097400; GO:1901224; GO:1904996; GO:2000679 6069 XM_029325247.2 7 10 18 98 28 NA NA NA NA NA NA 6070 XM_029346872.2 138 52 55 0 74 Q8R2S1 3e-51 Ribosomal protein S6 kinase-like 1 (EC 2.7.11.1) Mus musculus (Mouse) protein phosphorylation [GO:0006468] GO:0004674; GO:0005524; GO:0005840; GO:0006468; GO:0106310; GO:1990904 6071 XR_006394179.1 5 6 2 16 0 NA NA NA NA NA NA 6072 XM_044318047.1 192 213 76 46 83 Q5I0K3 1.29e-70 Citramalyl-CoA lyase, mitochondrial (EC 4.1.3.25) ((3S)-malyl-CoA thioesterase) (EC 3.1.2.30) (Beta-methylmalate synthase) (EC 2.3.3.-) (Citrate lyase subunit beta-like protein, mitochondrial) (Citrate lyase beta-like) (Malate synthase) (EC 2.3.3.9) Rattus norvegicus (Rat) positive regulation of cobalamin metabolic process [GO:0106121]; protein homotrimerization [GO:0070207]; regulation of cobalamin metabolic process [GO:0106064] GO:0000287; GO:0004474; GO:0005739; GO:0016787; GO:0047777; GO:0070207; GO:0106064; GO:0106121 6073 XM_029349978.2 19 0 10 6 0 NA NA NA NA NA NA 6074 XM_044325479.1 0 6 93 11 3 NA NA NA NA NA NA 6075 XR_006392824.1 19 0 32 14 40 NA NA NA NA NA NA 6076 XM_029336290.2 671 433 567 614 585 A0A2B4RP11 4.07e-131 NA NA NA NA 6077 XM_044307053.1 15 9 11 7 2 NA NA NA NA NA NA 6078 XM_044307279.1 43 58 0 0 145 Q61382 6.89e-38 TNF receptor-associated factor 4 (EC 2.3.2.27) (Cysteine-rich motif associated to RING and Traf domains protein 1) Mus musculus (Mouse) activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; innate immune response [GO:0045087]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein kinase activity [GO:0045860]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; respiratory gaseous exchange by respiratory system [GO:0007585]; respiratory tube development [GO:0030323] GO:0001650; GO:0005164; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0005923; GO:0006915; GO:0007250; GO:0007585; GO:0008270; GO:0016740; GO:0019901; GO:0030323; GO:0031625; GO:0031996; GO:0042802; GO:0042981; GO:0043122; GO:0043161; GO:0045087; GO:0045860; GO:0046330; GO:0048471; GO:0050699 6079 XM_029336007.2 571 225 222 491 452 Q94AM1 0 Organellar oligopeptidase A, chloroplastic/mitochondrial (EC 3.4.24.70) (Thimet metalloendopeptidase 1) (Zincin-like metalloproteases family protein 1) Arabidopsis thaliana (Mouse-ear cress) peptide metabolic process [GO:0006518]; proteolysis [GO:0006508] GO:0004222; GO:0005759; GO:0006508; GO:0006518; GO:0009507; GO:0009536; GO:0009570; GO:0046872 6080 XM_029340861.2 13075 9542 5921 13436 9054 Q63046 1.26e-72 Runt-related transcription factor 1 (Acute myeloid leukemia 1 protein) (Core-binding factor subunit alpha-2) (CBF-alpha-2) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEA2-alpha B) (PEBP2-alpha B) Rattus norvegicus (Rat) behavioral response to pain [GO:0048266]; cellular response to transforming growth factor beta stimulus [GO:0071560]; central nervous system development [GO:0007417]; chondrocyte differentiation [GO:0002062]; definitive hemopoiesis [GO:0060216]; embryonic hemopoiesis [GO:0035162]; hair follicle morphogenesis [GO:0031069]; hemopoiesis [GO:0030097]; in utero embryonic development [GO:0001701]; liver development [GO:0001889]; myeloid cell differentiation [GO:0030099]; myeloid leukocyte differentiation [GO:0002573]; myeloid progenitor cell differentiation [GO:0002318]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron development [GO:0048666]; neuron differentiation [GO:0030182]; neuron fate commitment [GO:0048663]; ossification [GO:0001503]; ovulation [GO:0030728]; positive regulation of angiogenesis [GO:0045766]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of cell maturation [GO:1903431]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of progesterone secretion [GO:2000872]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type II interferon production [GO:0032729]; regulation of cell differentiation [GO:0045595]; regulation of DNA-templated transcription [GO:0006355]; regulation of hair follicle cell proliferation [GO:0071336]; regulation of signal transduction [GO:0009966]; regulation of T cell anergy [GO:0002667]; regulation of transcription by RNA polymerase II [GO:0006357]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; response to retinoic acid [GO:0032526]; skeletal system development [GO:0001501] GO:0000122; GO:0000785; GO:0000976; GO:0000977; GO:0000978; GO:0000981; GO:0001222; GO:0001228; GO:0001501; GO:0001503; GO:0001701; GO:0001889; GO:0002062; GO:0002318; GO:0002573; GO:0002667; GO:0003677; GO:0003700; GO:0005524; GO:0005604; GO:0005634; GO:0006355; GO:0006357; GO:0007417; GO:0008285; GO:0009966; GO:0014894; GO:0016513; GO:0030097; GO:0030099; GO:0030182; GO:0030728; GO:0030854; GO:0031069; GO:0032526; GO:0032729; GO:0032743; GO:0035162; GO:0043371; GO:0043378; GO:0045595; GO:0045766; GO:0045892; GO:0045893; GO:0045944; GO:0048266; GO:0048663; GO:0048666; GO:0060216; GO:0071336; GO:0071560; GO:0140297; GO:1903431; GO:1990837; GO:1990841; GO:2000872 6081 XR_003825509.2 11 8 5 1 14 NA NA NA NA NA NA 6082 XM_044327239.1 75 10 78 54 118 NA NA NA NA NA NA 6083 XM_029353948.2 1622 1326 951 908 913 Q8TBP0 1.57e-134 TBC1 domain family member 16 Homo sapiens (Human) activation of GTPase activity [GO:0090630]; regulation of receptor recycling [GO:0001919] GO:0001919; GO:0005096; GO:0005769; GO:0005829; GO:0090630 6084 XM_044311737.1 9 0 8 2 11 Q96AY4 3.33e-56 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6085 XM_044311737.1 9 0 8 2 11 Q96AY4 1.28e-52 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6086 XM_044311737.1 9 0 8 2 11 Q96AY4 6.94e-51 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6087 XM_044311737.1 9 0 8 2 11 Q96AY4 1.25e-47 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6088 XM_044311737.1 9 0 8 2 11 Q96AY4 2.74e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6089 XM_044311737.1 9 0 8 2 11 Q96AY4 3.26e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6090 XM_044311737.1 9 0 8 2 11 Q96AY4 1.6e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6091 XM_044311737.1 9 0 8 2 11 Q96AY4 5.28e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6092 XM_044311737.1 9 0 8 2 11 Q96AY4 6.04e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6093 XM_044311737.1 9 0 8 2 11 Q96AY4 4.6e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6094 XM_044311737.1 9 0 8 2 11 Q96AY4 1.51e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6095 XM_044311737.1 9 0 8 2 11 Q96AY4 1.99e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6096 XM_044311737.1 9 0 8 2 11 Q96AY4 2.7e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6097 XR_003823836.2 4 0 8 1 31 NA NA NA NA NA NA 6098 XM_029346841.2 242 161 0 476 316 Q95YJ5 0 Thioredoxin domain-containing protein 3 homolog (Dynein intermediate chain 3) Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis) cell differentiation [GO:0030154]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside diphosphate phosphorylation [GO:0006165]; spermatogenesis [GO:0007283]; UTP biosynthetic process [GO:0006228] GO:0004550; GO:0006165; GO:0006183; GO:0006228; GO:0006241; GO:0007283; GO:0030154 6099 XM_044322746.1 9 15 8 12 3 NA NA NA NA NA NA 6100 XM_029324502.2 29 4 31 13 0 NA NA NA NA NA NA 6101 XR_006392290.1 377 23 32 135 92 NA NA NA NA NA NA 6102 XM_044318557.1 61 74 28 199 128 NA NA NA NA NA NA 6103 XM_044322235.1 0 0 0 51 0 NA NA NA NA NA NA 6104 XM_029326599.2 0 0 0 89 45 P11617 6.79e-28 Adenosine receptor A2a Canis lupus familiaris (Dog) (Canis familiaris) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; apoptotic signaling pathway [GO:0097190]; eating behavior [GO:0042755]; G protein-coupled adenosine receptor signaling pathway [GO:0001973]; G protein-coupled receptor signaling pathway [GO:0007186]; inhibitory postsynaptic potential [GO:0060080]; locomotory behavior [GO:0007626]; negative regulation of alpha-beta T cell activation [GO:0046636]; negative regulation of inflammatory response [GO:0050728]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; response to amphetamine [GO:0001975]; response to inorganic substance [GO:0010035]; response to purine-containing compound [GO:0014074]; synaptic transmission, dopaminergic [GO:0001963] GO:0001609; GO:0001963; GO:0001973; GO:0001975; GO:0004930; GO:0005886; GO:0007186; GO:0007189; GO:0007626; GO:0008289; GO:0010035; GO:0014074; GO:0019899; GO:0032230; GO:0042755; GO:0042802; GO:0046636; GO:0050728; GO:0060080; GO:0097190; GO:0098794; GO:2001235 6105 XM_029348380.2 1284 1207 1238 1666 1243 P54611 1.35e-86 V-type proton ATPase subunit E (V-ATPase subunit E) (V-ATPase 26 kDa subunit) (Vacuolar proton pump subunit E) Drosophila melanogaster (Fruit fly) apical protein localization [GO:0045176]; liquid clearance, open tracheal system [GO:0035002]; proton transmembrane transport [GO:1902600]; terminal branching, open tracheal system [GO:0007430] GO:0000221; GO:0005886; GO:0007430; GO:0033181; GO:0035002; GO:0045176; GO:0046961; GO:1902600 6106 XM_029328970.2 170 325 171 85 493 P04353 3.78e-45 Calmodulin (CaM) Spinacia oleracea (Spinach) NA GO:0005509 6107 XR_006396468.1 14 147 144 252 35 NA NA NA NA NA NA 6108 XM_029330657.2 48 43 30 21 17 Q6PFY8 3.88e-37 Tripartite motif-containing protein 45 Mus musculus (Mouse) bone development [GO:0060348]; positive regulation of DNA-templated transcription [GO:0045893] GO:0000785; GO:0004842; GO:0005654; GO:0005829; GO:0008270; GO:0045171; GO:0045893; GO:0060348 6109 XM_044325437.1 0 0 35 0 12 Q6QNK2 2.31e-63 Adhesion G-protein coupled receptor D1 (G-protein coupled receptor 133) (G-protein coupled receptor PGR25) Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0005654; GO:0005886; GO:0007166; GO:0007186; GO:0007189; GO:0016020 6110 XM_044326215.1 40 18 26 23 156 Q96AY4 7.6e-158 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6111 XM_044326215.1 40 18 26 23 156 Q96AY4 2.02e-149 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6112 XM_044326215.1 40 18 26 23 156 Q96AY4 9.68e-117 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6113 XM_044326215.1 40 18 26 23 156 Q96AY4 3.1e-51 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6114 XM_044326215.1 40 18 26 23 156 Q96AY4 6.69e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6115 XM_044327600.1 222 50 176 323 548 NA NA NA NA NA NA 6116 XM_029343165.2 218 209 56 134 200 Q61184 1.01e-23 Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor) Mus musculus (Mouse) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; circadian rhythm [GO:0007623]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of insulin secretion [GO:0046676] GO:0004930; GO:0005886; GO:0007186; GO:0007193; GO:0007623; GO:0008502; GO:0042562; GO:0043025; GO:0043235; GO:0046676; GO:0097159 6117 XM_029335762.2 396 66 258 373 345 Q9Y251 1.04e-104 Heparanase (EC 3.2.1.166) (Endo-glucoronidase) (Heparanase-1) (Hpa1) [Cleaved into: Heparanase 8 kDa subunit; Heparanase 50 kDa subunit] Homo sapiens (Human) angiogenesis involved in wound healing [GO:0060055]; cell-matrix adhesion [GO:0007160]; establishment of endothelial barrier [GO:0061028]; Factor XII activation [GO:0002542]; heparan sulfate proteoglycan catabolic process [GO:0030200]; heparin metabolic process [GO:0030202]; inflammatory response [GO:0006954]; positive regulation of angiogenesis [GO:0045766]; positive regulation of autophagy [GO:0010508]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of hair follicle development [GO:0051798]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vascular endothelial growth factor production [GO:0010575]; protein transmembrane transport [GO:0071806]; proteoglycan metabolic process [GO:0006029]; regulation of hair follicle development [GO:0051797]; response to organic substance [GO:0010033]; vascular wound healing [GO:0061042] GO:0001954; GO:0002542; GO:0004566; GO:0005576; GO:0005615; GO:0005634; GO:0005654; GO:0005764; GO:0005765; GO:0005768; GO:0005776; GO:0006029; GO:0006954; GO:0007160; GO:0008284; GO:0010033; GO:0010508; GO:0010575; GO:0030194; GO:0030200; GO:0030202; GO:0030305; GO:0030335; GO:0031012; GO:0033690; GO:0035580; GO:0043202; GO:0043231; GO:0045121; GO:0045545; GO:0045766; GO:0051797; GO:0051798; GO:0051897; GO:0060055; GO:0061028; GO:0061042; GO:0071806; GO:0090091; GO:1900026; GO:1904974 6118 XM_029330013.2 2 77 0 0 3 Q9Y2M2 1.51e-73 Protein SSUH2 homolog (Protein ssu-2 homolog) Homo sapiens (Human) odontogenesis [GO:0042476] GO:0005634; GO:0005737; GO:0031072; GO:0042476; GO:0051082 6119 XM_029356803.2 24 256 119 59 75 Q21415 2.06e-82 Glutamate receptor ionotropic, kainate glr-3 Caenorhabditis elegans detection of cold stimulus involved in thermoception [GO:0120169]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; modulation of chemical synaptic transmission [GO:0050804]; synaptic transmission, glutamatergic [GO:0035249] GO:0004970; GO:0005886; GO:0008066; GO:0015276; GO:0035249; GO:0038023; GO:0045211; GO:0050804; GO:0050965; GO:0120169; GO:1904315 6120 XM_029329190.2 13529 12277 7418 10422 8108 Q63413 0 Spliceosome RNA helicase Ddx39b (EC 3.6.4.13) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (DEAD box protein Uap56) Rattus norvegicus (Rat) liver development [GO:0001889]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of translation [GO:0045727]; positive regulation of vascular associated smooth muscle cell proliferation [GO:1904707]; RNA secondary structure unwinding [GO:0010501]; RNA splicing [GO:0008380]; spliceosomal complex assembly [GO:0000245]; viral mRNA export from host cell nucleus [GO:0046784] GO:0000245; GO:0000346; GO:0000398; GO:0001889; GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005681; GO:0005687; GO:0005688; GO:0005737; GO:0006406; GO:0008186; GO:0008380; GO:0010501; GO:0016363; GO:0016607; GO:0016887; GO:0017070; GO:0030621; GO:0032786; GO:0032991; GO:0042802; GO:0043008; GO:0044877; GO:0045727; GO:0046784; GO:0061051; GO:1904707; GO:2000002; GO:2000573 6121 XM_029335798.2 289 92 397 604 319 NA NA NA NA NA NA 6122 XM_044307182.1 71 34 9 0 4 NA NA NA NA NA NA 6123 XM_044310386.1 12 14 26 24 46 Q8VHE6 1.47e-62 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5) Mus musculus (Mouse) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0003777; GO:0005524; GO:0005576; GO:0005737; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 6124 XM_029338985.2 12 0 2 3 16 NA NA NA NA NA NA 6125 XM_044327744.1 91 112 212 166 213 NA NA NA NA NA NA 6126 XM_044307431.1 33 23 18 60 97 A1L1W9 9.42e-35 Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10) Danio rerio (Zebrafish) (Brachydanio rerio) aromatic amino acid transport [GO:0015801]; thyroid hormone transport [GO:0070327] GO:0005302; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0070327 6127 XR_006394809.1 26 59 58 52 47 NA NA NA NA NA NA 6128 XM_044328346.1 85 38 71 111 72 Q5SVZ6 6.19e-61 Zinc finger MYM-type protein 1 Homo sapiens (Human) NA GO:0005634; GO:0008270; GO:0046983 6129 XM_029338127.2 68 0 276 107 0 P08510 8.96e-88 Potassium voltage-gated channel protein Shaker (Protein minisleep) Drosophila melanogaster (Fruit fly) action potential [GO:0001508]; axon extension [GO:0048675]; behavioral response to ether [GO:0048150]; cellular response to dopamine [GO:1903351]; courtship behavior [GO:0007619]; detection of visible light [GO:0009584]; larval locomotory behavior [GO:0008345]; learning or memory [GO:0007611]; mating behavior, sex discrimination [GO:0048047]; positive regulation of circadian sleep/wake cycle, sleep [GO:0045938]; positive regulation of membrane potential [GO:0045838]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; proboscis extension reflex [GO:0007637]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; regulation of ion transmembrane transport [GO:0034765]; regulation of synaptic activity [GO:0060025]; sensory perception of taste [GO:0050909]; sleep [GO:0030431] GO:0001508; GO:0005249; GO:0005251; GO:0006813; GO:0007611; GO:0007619; GO:0007637; GO:0008076; GO:0008345; GO:0009584; GO:0016020; GO:0022843; GO:0030431; GO:0034765; GO:0045187; GO:0045838; GO:0045938; GO:0048047; GO:0048150; GO:0048675; GO:0050909; GO:0051260; GO:0060025; GO:0071805; GO:1903351 6130 XM_044317785.1 8790 9597 5535 5885 3878 NA NA NA NA NA NA 6131 XM_044324188.1 407 265 0 449 653 Q9UPU7 9.82e-51 TBC1 domain family member 2B Homo sapiens (Human) activation of GTPase activity [GO:0090630]; endocytosis [GO:0006897] GO:0005096; GO:0005769; GO:0005829; GO:0006897; GO:0090630 6132 XR_006392942.1 41 2 25 5 151 NA NA NA NA NA NA 6133 XM_044308885.1 66 252 84 118 306 NA NA NA NA NA NA 6134 XM_029337290.1 783 608 376 860 826 Q9CYH6 2.1e-75 Ribosome biogenesis regulatory protein homolog Mus musculus (Mouse) endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000447]; hematopoietic progenitor cell differentiation [GO:0002244]; mitotic metaphase plate congression [GO:0007080]; protein localization to nucleolus [GO:1902570]; regulation of signal transduction by p53 class mediator [GO:1901796]; ribosomal large subunit assembly [GO:0000027]; ribosomal large subunit biogenesis [GO:0042273]; ribosomal large subunit export from nucleus [GO:0000055] GO:0000027; GO:0000055; GO:0000447; GO:0000794; GO:0002244; GO:0005654; GO:0005730; GO:0005783; GO:0007080; GO:0008097; GO:0030687; GO:0042273; GO:1901796; GO:1902570 6135 XM_044311260.1 2 2 0 2 24 NA NA NA NA NA NA 6136 XM_044310852.1 3 8 0 14 6 NA NA NA NA NA NA 6137 XM_029351951.2 674 844 839 816 424 P10079 9.54e-24 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 6138 XR_006394148.1 0 15 0 34 0 NA NA NA NA NA NA 6139 XM_029346530.2 277 191 63 144 186 Q9I8C7 7.15e-93 Neuronal acetylcholine receptor subunit alpha-10 (Alpha 10 nAChR) (Nicotinic acetylcholine receptor subunit alpha-10) (NACHR alpha-10) Gallus gallus (Chicken) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; response to auditory stimulus [GO:0010996]; signal transduction [GO:0007165] GO:0004888; GO:0005231; GO:0005262; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0010996; GO:0022848; GO:0030594; GO:0034220; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051899; GO:1904315 6140 XR_006391361.1 1 0 0 3 19 NA NA NA NA NA NA 6141 XM_044323121.1 203 14 18 18 9 NA NA NA NA NA NA 6142 XM_029335875.2 1380 623 1126 1243 932 NA NA NA NA NA NA 6143 XM_029349046.2 5 0 4 0 26 NA NA NA NA NA NA 6144 XM_029334611.2 500 256 19 33 354 Q921L8 0 Polypeptide N-acetylgalactosaminyltransferase 11 (EC 2.4.1.41) (Polypeptide GalNAc transferase 11) (GalNAc-T11) (pp-GaNTase 11) (Protein-UDP acetylgalactosaminyltransferase 11) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 11) Mus musculus (Mouse) cilium assembly [GO:0060271]; determination of left/right symmetry [GO:0007368]; Notch receptor processing [GO:0007220]; Notch signaling involved in heart development [GO:0061314]; protein O-linked glycosylation [GO:0006493]; protein O-linked glycosylation via threonine [GO:0018243]; regulation of Notch signaling pathway [GO:0008593] GO:0000139; GO:0004653; GO:0005112; GO:0005794; GO:0006493; GO:0007220; GO:0007368; GO:0008593; GO:0018243; GO:0030246; GO:0046872; GO:0060271; GO:0061314 6145 XM_029335671.2 649 411 290 497 389 D4AD37 3.6e-87 Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase (Golgi-resident PAP phosphatase) (gPAPP) (EC 3.1.3.7) (3'(2'), 5'-bisphosphate nucleotidase 2) (Inositol monophosphatase domain-containing protein 1) (Myo-inositol monophosphatase A3) (Phosphoadenosine phosphate 3'-nucleotidase) Rattus norvegicus (Rat) chondrocyte development [GO:0002063]; chondroitin sulfate metabolic process [GO:0030204]; embryonic digit morphogenesis [GO:0042733]; endochondral ossification [GO:0001958]; inositol phosphate dephosphorylation [GO:0046855]; phosphatidylinositol phosphate biosynthetic process [GO:0046854]; post-embryonic development [GO:0009791]; skeletal system development [GO:0001501] GO:0001501; GO:0001958; GO:0002063; GO:0008254; GO:0008441; GO:0009791; GO:0012505; GO:0030204; GO:0032588; GO:0042733; GO:0046854; GO:0046855; GO:0046872; GO:0097657 6146 XM_044312017.1 0 21 7 39 0 Q58A42 7.83e-68 Protein DD3-3 Dictyostelium discoideum (Social amoeba) NA GO:0016020 6147 XM_029342491.2 1438 338 218 271 1550 NA NA NA NA NA NA 6148 XR_006395650.1 112 224 68 69 189 NA NA NA NA NA NA 6149 XM_044311870.1 7 0 0 3 2 NA NA NA NA NA NA 6150 XM_029337198.2 4451 7657 2685 8275 6742 Q28DT9 2.64e-73 SPRY domain-containing SOCS box protein 3 (SSB-3) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) protein ubiquitination [GO:0016567] GO:0016567 6151 XM_044315652.1 214 190 242 127 275 NA NA NA NA NA NA 6152 XM_044319510.1 2942 2386 6 29 1281 Q5R9T9 5.7e-41 Guanylate-binding protein 6 (EC 3.6.5.-) (GTP-binding protein 6) (GBP-6) (Guanine nucleotide-binding protein 6) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cellular response to type II interferon [GO:0071346]; defense response to bacterium [GO:0042742]; immune response [GO:0006955] GO:0003924; GO:0005525; GO:0006955; GO:0031410; GO:0042742; GO:0071346 6153 XM_029358213.2 715 632 511 522 461 Q5RES3 1.14e-22 LYR motif-containing protein 2 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA NA 6154 XR_006394076.1 55 51 0 55 42 NA NA NA NA NA NA 6155 XM_044316799.1 0 216 0 0 93 Q2LE78 1.5e-62 BTB/POZ domain-containing protein 6 Xenopus laevis (African clawed frog) NA GO:0005737 6156 XM_029340391.2 273 2 0 0 0 E9QAT4 1.14e-45 Protein transport protein Sec16A (SEC16 homolog A) (p250) Mus musculus (Mouse) autophagy [GO:0006914]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; Golgi to plasma membrane transport [GO:0006893]; protein exit from endoplasmic reticulum [GO:0032527]; protein localization to endoplasmic reticulum exit site [GO:0070973]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; response to endoplasmic reticulum stress [GO:0034976] GO:0000139; GO:0005789; GO:0005829; GO:0006888; GO:0006893; GO:0006914; GO:0007029; GO:0007030; GO:0012507; GO:0031090; GO:0032527; GO:0034976; GO:0048208; GO:0048471; GO:0050821; GO:0070971; GO:0070973; GO:0072659 6157 XM_029331869.2 1715 1457 713 1687 1132 Q4R8T1 1.2e-34 EF-hand calcium-binding domain-containing protein 6 (DJ-1-binding protein) (DJBP) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0005509; GO:0005634; GO:0005737; GO:0005856; GO:0042995 6158 XR_006394259.1 11 4 43 9 189 NA NA NA NA NA NA 6159 XM_029332194.2 4 9 3 9 10 NA NA NA NA NA NA 6160 XM_029331378.2 631 538 236 455 428 Q8R512 1.83e-81 UBX domain-containing protein 11 (Socius) (UBX domain-containing protein 5) Rattus norvegicus (Rat) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] GO:0005737; GO:0005856; GO:0043130; GO:0043161 6161 XM_044307812.1 16 7 5 0 3 NA NA NA NA NA NA 6162 XM_029336252.2 7 38 0 15 34 F1PZV2 4.68e-21 Major facilitator superfamily domain-containing protein 12 Canis lupus familiaris (Dog) (Canis familiaris) carbohydrate transport [GO:0008643]; cysteine transmembrane transport [GO:1903712]; melanin biosynthetic process [GO:0042438]; organic substance transport [GO:0071702]; pigment metabolic process involved in pigmentation [GO:0043474]; regulation of melanin biosynthetic process [GO:0048021] GO:0005764; GO:0005765; GO:0005886; GO:0008643; GO:0015293; GO:0033162; GO:0033229; GO:0042438; GO:0043474; GO:0048021; GO:0071702; GO:1903712 6163 XM_044323786.1 399 180 195 269 600 G8HTB6 1.44e-27 ZP domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 6164 XR_006393191.1 12 7 22 20 9 NA NA NA NA NA NA 6165 XM_044315400.1 9 3 20 3 29 NA NA NA NA NA NA 6166 XM_044328110.1 81 0 89 0 22 NA NA NA NA NA NA 6167 XM_044328481.1 74 32 24 58 33 Q91611 7.97e-31 Desert hedgehog protein B (EC 3.1.-.-) (Desert hedgehog protein 2) (DHH-2) (Hedgehog protein 4) (X-HH4) [Cleaved into: Desert hedgehog protein B N-product] Xenopus laevis (African clawed frog) cell-cell signaling [GO:0007267]; positive regulation of smoothened signaling pathway [GO:0045880]; protein autoprocessing [GO:0016540]; self proteolysis [GO:0097264] GO:0000139; GO:0005113; GO:0005576; GO:0005789; GO:0005886; GO:0007267; GO:0008233; GO:0016540; GO:0045880; GO:0046872; GO:0097264; GO:0140853 6168 XM_044312818.1 36 22 24 58 28 Q96AY4 1.48e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6169 XM_044325582.1 81 72 72 29 34 NA NA NA NA NA NA 6170 XM_029346205.2 72 38 48 66 36 Q9Y5X5 7.07e-22 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (G-protein coupled receptor HLWAR77) (Neuropeptide G-protein coupled receptor) Homo sapiens (Human) detection of abiotic stimulus [GO:0009582]; G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0009582; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 6171 XR_006395107.1 107 70 133 176 249 Q76KP1 2.96e-53 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Homo sapiens (Human) NA GO:0008376; GO:0032580; GO:0033842 6172 XR_006395107.1 107 70 133 176 249 Q76KP1 1.1e-22 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Homo sapiens (Human) NA GO:0008376; GO:0032580; GO:0033842 6173 XR_006394939.1 410 88 402 99 1043 NA NA NA NA NA NA 6174 XM_029357655.2 100 75 51 233 81 NA NA NA NA NA NA 6175 XM_029354109.2 12 0 0 0 0 Q91175 6.22e-48 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (MAR1) Oryzias latipes (Japanese rice fish) (Japanese killifish) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of vasoconstriction [GO:0045907] GO:0001996; GO:0004930; GO:0004937; GO:0005886; GO:0007200; GO:0007204; GO:0007267; GO:0043410; GO:0045907; GO:0071880 6176 XM_029330745.2 2172 1533 831 1815 1335 Q7ZTY4 0 Histone-binding protein RBBP7 (Retinoblastoma-binding protein 7) (RBBP-7) Danio rerio (Zebrafish) (Brachydanio rerio) chromatin remodeling [GO:0006338]; DNA replication [GO:0006260]; fin regeneration [GO:0031101]; hematopoietic progenitor cell differentiation [GO:0002244]; histone deacetylation [GO:0016575]; regulation of DNA-templated transcription [GO:0006355] GO:0002244; GO:0005634; GO:0006260; GO:0006338; GO:0006355; GO:0016575; GO:0016581; GO:0031101; GO:0035098; GO:0042393 6177 XM_044326192.1 41 50 39 62 47 Q96AY4 1.63e-88 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6178 XM_044326192.1 41 50 39 62 47 Q96AY4 2.01e-86 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6179 XM_044326192.1 41 50 39 62 47 Q96AY4 3.96e-85 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6180 XM_044326192.1 41 50 39 62 47 Q96AY4 4.14e-81 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6181 XM_044326192.1 41 50 39 62 47 Q96AY4 2.79e-76 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6182 XM_044326192.1 41 50 39 62 47 Q96AY4 7.11e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6183 XM_029335308.2 367 253 180 251 227 O95336 3.73e-56 6-phosphogluconolactonase (6PGL) (EC 3.1.1.31) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, oxidative branch [GO:0009051] GO:0005737; GO:0005829; GO:0005975; GO:0006098; GO:0009051; GO:0017057; GO:0070062 6184 XR_006392782.1 0 46 3 0 0 NA NA NA NA NA NA 6185 XM_044323269.1 9 1 8 4 2 NA NA NA NA NA NA 6186 XM_029347705.2 793 463 452 460 702 NA NA NA NA NA NA 6187 XR_006393323.1 11 0 64 0 9 NA NA NA NA NA NA 6188 XR_006393447.1 25 21 35 1 59 NA NA NA NA NA NA 6189 XM_029329885.2 829 650 388 956 527 NA NA NA NA NA NA 6190 XM_029352968.2 279 209 439 1122 387 O96024 6.83e-27 Beta-1,3-galactosyltransferase 4 (Beta-1,3-GalTase 4) (Beta3Gal-T4) (Beta3GalT4) (GalT4) (b3Gal-T4) (EC 2.4.1.62) (Gal-T2) (Ganglioside galactosyltransferase) (UDP-galactose:beta-N-acetyl-galactosamine-beta-1,3-galactosyltransferase) Homo sapiens (Human) ganglioside biosynthetic process [GO:0001574]; oligosaccharide biosynthetic process [GO:0009312]; protein glycosylation [GO:0006486] GO:0000139; GO:0001574; GO:0006486; GO:0008499; GO:0009312; GO:0016757; GO:0019901; GO:0022627; GO:0047915 6191 XM_044308487.1 449 354 232 115 96 NA NA NA NA NA NA 6192 XM_029323877.2 397 199 421 234 808 A0A1J6KGJ9 1.27e-53 Jasmonoyl--L-amino acid synthetase JAR4 (EC 6.3.2.52) (Jasmonate-amino acid synthetase JAR4) (Jasmonic acid-amido synthetase JAR4) (Protein JASMONATE RESISTANT 4) Nicotiana attenuata (Coyote tobacco) defense response [GO:0006952] GO:0005524; GO:0006952; GO:0102053; GO:0102057; GO:0102058 6193 XM_029326864.2 1325 520 639 896 1195 NA NA NA NA NA NA 6194 XM_029344538.2 2379 762 1048 1388 1460 Q6AWC2 1.52e-62 Protein WWC2 (BH-3-only member B) (WW domain-containing protein 2) Homo sapiens (Human) cell migration [GO:0016477]; negative regulation of hippo signaling [GO:0035331]; negative regulation of organ growth [GO:0046621]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355]; regulation of hippo signaling [GO:0035330] GO:0000122; GO:0005737; GO:0005829; GO:0006355; GO:0016477; GO:0019900; GO:0035330; GO:0035331; GO:0046621; GO:0060090 6195 XM_029337748.2 180 211 0 342 44 P13697 0 NADP-dependent malic enzyme (NADP-ME) (EC 1.1.1.40) (Malic enzyme 1) Rattus norvegicus (Rat) malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; NADP metabolic process [GO:0006739]; protein homotetramerization [GO:0051289]; pyruvate metabolic process [GO:0006090]; regulation of NADP metabolic process [GO:1902031]; response to hormone [GO:0009725] GO:0000287; GO:0004470; GO:0004471; GO:0004473; GO:0005737; GO:0005739; GO:0005829; GO:0006090; GO:0006108; GO:0006734; GO:0006739; GO:0008948; GO:0009725; GO:0030145; GO:0042802; GO:0050661; GO:0051287; GO:0051289; GO:1902031 6196 XM_029332854.2 222 122 0 121 0 P97767 1.03e-153 Eyes absent homolog 1 (EC 3.1.3.16) (EC 3.1.3.48) Mus musculus (Mouse) anatomical structure development [GO:0048856]; animal organ morphogenesis [GO:0009887]; aorta morphogenesis [GO:0035909]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chromatin organization [GO:0006325]; cochlea morphogenesis [GO:0090103]; double-strand break repair [GO:0006302]; embryonic skeletal system morphogenesis [GO:0048704]; epithelial cell proliferation [GO:0050673]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; inner ear morphogenesis [GO:0042472]; mesodermal cell fate specification [GO:0007501]; metanephros development [GO:0001656]; middle ear morphogenesis [GO:0042474]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; neuron fate specification [GO:0048665]; otic vesicle development [GO:0071599]; otic vesicle morphogenesis [GO:0071600]; outer ear morphogenesis [GO:0042473]; outflow tract morphogenesis [GO:0003151]; pattern specification process [GO:0007389]; pharyngeal system development [GO:0060037]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of secondary heart field cardioblast proliferation [GO:0072513]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein dephosphorylation [GO:0006470]; protein sumoylation [GO:0016925]; regulation of neuron differentiation [GO:0045664]; response to ionizing radiation [GO:0010212]; semicircular canal morphogenesis [GO:0048752]; striated muscle tissue development [GO:0014706]; ureteric bud development [GO:0001657] GO:0001656; GO:0001657; GO:0001658; GO:0003151; GO:0003723; GO:0004725; GO:0005634; GO:0005654; GO:0005737; GO:0006302; GO:0006325; GO:0006470; GO:0007389; GO:0007501; GO:0009887; GO:0010212; GO:0014706; GO:0016604; GO:0016925; GO:0017018; GO:0030154; GO:0032991; GO:0032993; GO:0035909; GO:0042472; GO:0042473; GO:0042474; GO:0045165; GO:0045664; GO:0045739; GO:0045893; GO:0045944; GO:0046872; GO:0048665; GO:0048704; GO:0048752; GO:0048856; GO:0050673; GO:0050679; GO:0060037; GO:0071599; GO:0071600; GO:0072513; GO:0090103; GO:0097192; GO:0140793; GO:2001240 6197 XM_044310785.1 17 4 7 7 10 NA NA NA NA NA NA 6198 XM_029357667.2 5785 4876 3906 7877 6233 Q91YT0 0 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (EC 7.1.1.2) (Complex I-51kD) (CI-51kD) (NADH-ubiquinone oxidoreductase 51 kDa subunit) Mus musculus (Mouse) aerobic respiration [GO:0009060]; mitochondrial ATP synthesis coupled electron transport [GO:0042775]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776] GO:0005739; GO:0005743; GO:0005747; GO:0005829; GO:0006120; GO:0008137; GO:0009060; GO:0010181; GO:0042775; GO:0042776; GO:0046872; GO:0051287; GO:0051539 6199 XM_029341274.2 1024 470 553 883 864 Q7RTR2 2.09e-39 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 6200 XM_029341274.2 1024 470 553 883 864 Q7RTR2 1.31e-38 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 6201 XM_029341274.2 1024 470 553 883 864 Q7RTR2 2.44e-34 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 6202 XM_029341274.2 1024 470 553 883 864 Q7RTR2 5.71e-28 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 6203 XM_029343888.2 502 460 196 366 336 P33215 5.65e-132 Protein NEDD1 (Neural precursor cell expressed developmentally down-regulated protein 1) (NEDD-1) Mus musculus (Mouse) cell division [GO:0051301]; microtubule depolymerization [GO:0007019]; microtubule nucleation [GO:0007020]; microtubule polymerization or depolymerization [GO:0031109]; mitotic cell cycle [GO:0000278]; regulation of establishment of protein localization [GO:0070201] GO:0000242; GO:0000278; GO:0000922; GO:0000931; GO:0001650; GO:0005654; GO:0005737; GO:0005813; GO:0005814; GO:0005829; GO:0007019; GO:0007020; GO:0031109; GO:0036064; GO:0043015; GO:0045177; GO:0051301; GO:0070201 6204 XM_029329702.2 160 145 116 167 333 Q9BRU9 1.46e-42 rRNA-processing protein UTP23 homolog Homo sapiens (Human) endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000480] GO:0000480; GO:0003723; GO:0003730; GO:0005730; GO:0032040; GO:0048027; GO:0070181 6205 XM_029327882.2 104 38 42 57 111 NA NA NA NA NA NA 6206 XM_044316833.1 0 127 57 249 0 NA NA NA NA NA NA 6207 XM_029352374.2 0 0 0 40 0 NA NA NA NA NA NA 6208 XM_029345441.2 185 159 50 423 211 Q867B0 5.27e-52 Chymotrypsin-like elastase family member 1 (EC 3.4.21.36) (Elastase-1) Canis lupus familiaris (Dog) (Canis familiaris) proteolysis [GO:0006508] GO:0004252; GO:0005615; GO:0006508; GO:0046872 6209 XM_044323604.1 5 259 193 0 0 NA NA NA NA NA NA 6210 XM_044315059.1 53 11 23 78 72 NA NA NA NA NA NA 6211 XR_003824372.2 0 0 0 7 0 NA NA NA NA NA NA 6212 XM_044314900.1 3 0 18 3 6 Q9U6Y6 1.79e-52 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 6213 XM_044312345.1 687 563 750 1086 509 NA NA NA NA NA NA 6214 XM_044319931.1 203 235 301 489 135 Q7ZU29 0 Nuclear pore complex protein Nup93 (93 kDa nucleoporin) (Dead eye protein) (Nucleoporin Nup93) Danio rerio (Zebrafish) (Brachydanio rerio) nuclear pore complex assembly [GO:0051292]; poly(A)+ mRNA export from nucleus [GO:0016973]; protein import into nucleus [GO:0006606] GO:0005643; GO:0006606; GO:0016973; GO:0017056; GO:0031965; GO:0034399; GO:0051292 6215 XM_044317920.1 4 4 3 3 7 NA NA NA NA NA NA 6216 XM_029346232.2 327 353 33 217 16 NA NA NA NA NA NA 6217 XM_029341597.2 576 387 430 802 821 B8V7S0 0 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 6218 XM_029341597.2 576 387 430 802 821 B8V7S0 1e-31 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 6219 XM_029341597.2 576 387 430 802 821 B8V7S0 4.42e-29 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 6220 XM_029341597.2 576 387 430 802 821 B8V7S0 3.78e-28 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 6221 XM_044315038.1 15 0 0 0 37 NA NA NA NA NA NA 6222 XM_029354375.2 9 0 12 35 23 NA NA NA NA NA NA 6223 XM_029355734.2 75 42 81 83 133 Q12950 5.67e-36 Forkhead box protein D4 (Forkhead-related protein FKHL9) (Forkhead-related transcription factor 5) (FREAC-5) (Myeloid factor-alpha) Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000785; GO:0000978; GO:0000981; GO:0003700; GO:0005634; GO:0006357; GO:0008301; GO:0009653; GO:0030154; GO:0043565 6224 XM_044323006.1 78 32 16 123 0 Q28ES4 2.63e-59 Solute carrier family 22 member 15-like Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) ion transport [GO:0006811] GO:0006811; GO:0016020; GO:0022857 6225 XM_044322721.1 0 0 0 0 91 Q8CBF3 3.53e-160 Ephrin type-B receptor 1 (EC 2.7.10.1) Mus musculus (Mouse) angiogenesis [GO:0001525]; axon guidance [GO:0007411]; camera-type eye morphogenesis [GO:0048593]; cell chemotaxis [GO:0060326]; cell-substrate adhesion [GO:0031589]; central nervous system projection neuron axonogenesis [GO:0021952]; cranial nerve development [GO:0021545]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; ephrin receptor signaling pathway [GO:0048013]; establishment of cell polarity [GO:0030010]; hindbrain tangential cell migration [GO:0021934]; immunological synapse formation [GO:0001771]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of satellite cell differentiation [GO:1902725]; negative regulation of skeletal muscle satellite cell proliferation [GO:1902723]; neural precursor cell proliferation [GO:0061351]; neurogenesis [GO:0022008]; optic nerve morphogenesis [GO:0021631]; positive regulation of kinase activity [GO:0033674]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of neuron death [GO:1901214]; retinal ganglion cell axon guidance [GO:0031290]; skeletal muscle satellite cell activation [GO:0014719]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0001525; GO:0001771; GO:0004713; GO:0004714; GO:0005005; GO:0005524; GO:0005737; GO:0005783; GO:0005829; GO:0005886; GO:0007169; GO:0007411; GO:0008046; GO:0014719; GO:0016020; GO:0021545; GO:0021631; GO:0021934; GO:0021952; GO:0022008; GO:0030010; GO:0030424; GO:0030425; GO:0031290; GO:0031589; GO:0031901; GO:0032433; GO:0033674; GO:0043005; GO:0043235; GO:0044877; GO:0045121; GO:0046328; GO:0046777; GO:0048013; GO:0048593; GO:0050804; GO:0050965; GO:0051965; GO:0060326; GO:0060996; GO:0060997; GO:0061351; GO:0070372; GO:0098978; GO:1901214; GO:1902723; GO:1902725 6226 XM_044329066.1 0 0 1 17 17 NA NA NA NA NA NA 6227 XM_029331576.2 6 62 7 242 18 NA NA NA NA NA NA 6228 XM_044316254.1 0 3 0 0 43 P81274 3.83e-30 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 6229 XM_044316254.1 0 3 0 0 43 P81274 3.01e-26 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 6230 XM_044316254.1 0 3 0 0 43 P81274 3.82e-23 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 6231 XM_029356353.2 1285 323 611 872 1003 A4D0V7 1.38e-110 Cadherin-like and PC-esterase domain-containing protein 1 Homo sapiens (Human) NA GO:0005783 6232 XM_044313172.1 11 3 2 20 24 NA NA NA NA NA NA 6233 XM_029355415.2 203 263 192 215 257 NA NA NA NA NA NA 6234 XM_029323837.2 3735 2772 2409 4295 4635 Q9HD45 0 Transmembrane 9 superfamily member 3 (EP70-P-iso) (SM-11044-binding protein) Homo sapiens (Human) protein localization to membrane [GO:0072657] GO:0016020; GO:0072657 6235 XM_044328571.1 2299 1682 1106 3305 3420 NA NA NA NA NA NA 6236 XM_044328738.1 97 31 45 73 208 NA NA NA NA NA NA 6237 XM_029334712.2 762 373 361 445 361 O54852 0 Potassium voltage-gated channel subfamily H member 7 (Ether-a-go-go-related gene potassium channel 3) (ERG-3) (Eag-related protein 3) (Ether-a-go-go-related protein 3) (Voltage-gated potassium channel subunit Kv11.3) Rattus norvegicus (Rat) circadian rhythm [GO:0007623]; membrane repolarization during action potential [GO:0086011]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391] GO:0005242; GO:0005249; GO:0005267; GO:0005886; GO:0006813; GO:0007623; GO:0034765; GO:0042391; GO:0044877; GO:0071805; GO:0086011 6238 XM_044308793.1 174 158 77 184 236 NA NA NA NA NA NA 6239 XM_029330710.2 152 127 433 0 0 A1L3F5 1.27e-103 C-Maf-inducing protein (c-Mip) Xenopus laevis (African clawed frog) NA GO:0005634; GO:0005737 6240 XM_029330710.2 152 127 433 0 0 A1L3F5 2.3e-87 C-Maf-inducing protein (c-Mip) Xenopus laevis (African clawed frog) NA GO:0005634; GO:0005737 6241 XR_006397413.1 57 18 46 28 160 NA NA NA NA NA NA 6242 XM_044320329.1 0 7 0 18 2 NA NA NA NA NA NA 6243 XM_044320292.1 0 52 25 94 0 NA NA NA NA NA NA 6244 XR_006394267.1 11 4 43 9 189 NA NA NA NA NA NA 6245 XM_044309240.1 0 7 8 1 19 NA NA NA NA NA NA 6246 XR_006395362.1 3 44 25 26 20 NA NA NA NA NA NA 6247 XM_044322491.1 305 390 168 560 486 Q5BK81 3.2e-98 Prostaglandin reductase 2 (PRG-2) (EC 1.3.1.48) (15-oxoprostaglandin 13-reductase) (Zinc-binding alcohol dehydrogenase domain-containing protein 1) Rattus norvegicus (Rat) prostaglandin metabolic process [GO:0006693] GO:0005737; GO:0006693; GO:0036132; GO:0047522 6248 XM_029350949.2 33 18 28 34 37 NA NA NA NA NA NA 6249 XM_029335871.2 696 511 441 900 1100 A6QLE6 4.51e-175 Anoctamin-4 (Transmembrane protein 16D) Bos taurus (Bovine) chloride transmembrane transport [GO:1902476]; lipid transport [GO:0006869]; transmembrane transport [GO:0055085] GO:0005229; GO:0005254; GO:0005886; GO:0006869; GO:0046983; GO:0055085; GO:1902476 6250 XM_044310708.1 2 0 15 13 16 NA NA NA NA NA NA 6251 XM_044325183.1 0 0 0 0 8 NA NA NA NA NA NA 6252 XM_029335209.2 3621 3158 1540 3455 2128 Q8K3X3 0 GDP-mannose 4,6 dehydratase (EC 4.2.1.47) (GDP-D-mannose dehydratase) (GMD) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) 'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; GDP-mannose metabolic process [GO:0019673]; Notch signaling pathway [GO:0007219] GO:0007219; GO:0008446; GO:0019673; GO:0042351; GO:0042802; GO:0070401 6253 XM_044322813.1 718 671 462 849 891 Q920Q4 0 Vacuolar protein sorting-associated protein 16 homolog (mVPS16) Mus musculus (Mouse) autophagosome maturation [GO:0097352]; endosomal transport [GO:0016197]; endosome to lysosome transport [GO:0008333]; intracellular protein transport [GO:0006886]; vacuole fusion, non-autophagic [GO:0042144]; viral entry into host cell [GO:0046718] GO:0003779; GO:0005764; GO:0005765; GO:0005768; GO:0005769; GO:0005770; GO:0005776; GO:0005884; GO:0006886; GO:0008333; GO:0016197; GO:0030136; GO:0030424; GO:0030897; GO:0031901; GO:0031902; GO:0033263; GO:0042144; GO:0043025; GO:0046718; GO:0051015; GO:0055037; GO:0097352; GO:0098793 6254 XM_044320944.1 4446 4058 3220 4584 4487 Q4LDD4 7.13e-50 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 (Centaurin-delta-2) (Cnt-d2) Mus musculus (Mouse) negative regulation of stress fiber assembly [GO:0051497]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of receptor recycling [GO:0001921]; regulation of cell shape [GO:0008360]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0000976; GO:0001921; GO:0003700; GO:0005096; GO:0005547; GO:0005654; GO:0005737; GO:0005794; GO:0005802; GO:0005829; GO:0005886; GO:0007179; GO:0008360; GO:0031410; GO:0031702; GO:0032580; GO:0043231; GO:0043547; GO:0045893; GO:0046872; GO:0051491; GO:0051497; GO:0060395; GO:0061629; GO:0070412 6255 XM_044320944.1 4446 4058 3220 4584 4487 Q4LDD4 8.87e-39 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 (Centaurin-delta-2) (Cnt-d2) Mus musculus (Mouse) negative regulation of stress fiber assembly [GO:0051497]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of receptor recycling [GO:0001921]; regulation of cell shape [GO:0008360]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0000976; GO:0001921; GO:0003700; GO:0005096; GO:0005547; GO:0005654; GO:0005737; GO:0005794; GO:0005802; GO:0005829; GO:0005886; GO:0007179; GO:0008360; GO:0031410; GO:0031702; GO:0032580; GO:0043231; GO:0043547; GO:0045893; GO:0046872; GO:0051491; GO:0051497; GO:0060395; GO:0061629; GO:0070412 6256 XM_029343811.2 253 159 85 194 144 NA NA NA NA NA NA 6257 XR_006397451.1 292 442 287 86 210 NA NA NA NA NA NA 6258 XM_044313886.1 0 0 0 0 6 NA NA NA NA NA NA 6259 XM_044325990.1 1668 0 0 306 397 NA NA NA NA NA NA 6260 XM_044307594.1 0 0 89 35 0 Q08C93 1.08e-60 Lysophosphatidylserine lipase ABHD12 (EC 3.1.-.-) (2-arachidonoylglycerol hydrolase ABHD12) (Abhydrolase domain-containing protein 12) (Monoacylglycerol lipase ABHD12) (EC 3.1.1.23) (Oxidized phosphatidylserine lipase ABHD12) (EC 3.1.-.-) Danio rerio (Zebrafish) (Brachydanio rerio) acylglycerol catabolic process [GO:0046464]; anterior lateral line development [GO:0048899]; camera-type eye development [GO:0043010]; monoacylglycerol catabolic process [GO:0052651]; myelination [GO:0042552]; phosphatidylserine catabolic process [GO:0006660]; phospholipid catabolic process [GO:0009395]; posterior lateral line neuromast development [GO:0048919]; retina layer formation [GO:0010842]; swimming behavior [GO:0036269] GO:0004620; GO:0004622; GO:0005789; GO:0006660; GO:0008474; GO:0009395; GO:0010842; GO:0016020; GO:0036269; GO:0042552; GO:0043010; GO:0046464; GO:0047372; GO:0048899; GO:0048919; GO:0052651 6261 XM_029330291.2 283 274 120 276 277 O08688 0 Calpain-5 (EC 3.4.22.-) (New calpain 3) (nCL-3) Mus musculus (Mouse) proteolysis [GO:0006508] GO:0004198; GO:0005737; GO:0006508; GO:0009986; GO:0045202 6262 XM_029341317.2 10 0 0 0 0 NA NA NA NA NA NA 6263 XR_006393575.1 306 163 176 356 287 Q7K4Y6 1.17e-142 Sodium-dependent dopamine transporter (Protein fumin) Drosophila melanogaster (Fruit fly) adult locomotory behavior [GO:0008344]; circadian sleep/wake cycle [GO:0042745]; dopamine transport [GO:0015872]; dopamine uptake involved in synaptic transmission [GO:0051583]; norepinephrine transport [GO:0015874]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509]; response to odorant [GO:1990834]; sleep [GO:0030431]; sodium ion transmembrane transport [GO:0035725] GO:0005330; GO:0005886; GO:0008344; GO:0015872; GO:0015874; GO:0019811; GO:0030431; GO:0032809; GO:0035725; GO:0042734; GO:0042745; GO:0043005; GO:0046872; GO:0051583; GO:0099509; GO:1990834 6264 XR_006393575.1 306 163 176 356 287 Q7K4Y6 1.17e-142 Sodium-dependent dopamine transporter (Protein fumin) Drosophila melanogaster (Fruit fly) adult locomotory behavior [GO:0008344]; circadian sleep/wake cycle [GO:0042745]; dopamine transport [GO:0015872]; dopamine uptake involved in synaptic transmission [GO:0051583]; norepinephrine transport [GO:0015874]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509]; response to odorant [GO:1990834]; sleep [GO:0030431]; sodium ion transmembrane transport [GO:0035725] GO:0005330; GO:0005886; GO:0008344; GO:0015872; GO:0015874; GO:0019811; GO:0030431; GO:0032809; GO:0035725; GO:0042734; GO:0042745; GO:0043005; GO:0046872; GO:0051583; GO:0099509; GO:1990834 6265 XM_029330280.2 89 73 29 71 73 NA NA NA NA NA NA 6266 XR_003828575.2 0 2 18 10 40 NA NA NA NA NA NA 6267 XM_029356294.2 350 187 165 221 165 NA NA NA NA NA NA 6268 XM_029343864.2 0 0 1 26 0 Q9CL21 8.8e-42 ATP-dependent DNA helicase RecQ (EC 3.6.4.12) Pasteurella multocida (strain Pm70) DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; SOS response [GO:0009432] GO:0003677; GO:0005524; GO:0006260; GO:0006281; GO:0006310; GO:0009432; GO:0016887; GO:0043138 6269 XM_044318873.1 856 1048 207 377 826 NA NA NA NA NA NA 6270 XM_029327376.2 615 324 151 229 472 Q4R550 0 Cysteine--tRNA ligase, cytoplasmic (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) cysteinyl-tRNA aminoacylation [GO:0006423] GO:0000049; GO:0004817; GO:0005524; GO:0005737; GO:0006423; GO:0046872 6271 XM_029349900.2 1090 1743 645 787 750 P53369 1.43e-51 Oxidized purine nucleoside triphosphate hydrolase (EC 3.6.1.56) (2-hydroxy-dATP diphosphatase) (7,8-dihydro-8-oxoguanine triphosphatase) (8-oxo-dGTPase) (Methylated purine nucleoside triphosphate hydrolase) (EC 3.6.1.-) (Nucleoside diphosphate-linked moiety X motif 1) (Nudix motif 1) Rattus norvegicus (Rat) aging [GO:0007568]; DNA protection [GO:0042262]; male gonad development [GO:0008584]; purine nucleoside catabolic process [GO:0006152]; response to cadmium ion [GO:0046686] GO:0001669; GO:0005615; GO:0005634; GO:0005737; GO:0005739; GO:0005759; GO:0005829; GO:0005886; GO:0006152; GO:0007568; GO:0008413; GO:0008584; GO:0008828; GO:0016818; GO:0030515; GO:0031965; GO:0035539; GO:0042262; GO:0046686; GO:0046872; GO:0047693; GO:0106377; GO:0106378; GO:0106431; GO:0106433 6272 XM_044315823.1 11 0 17 4 2 O75581 0 Low-density lipoprotein receptor-related protein 6 (LRP-6) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; chemical synaptic transmission [GO:0007268]; dopaminergic neuron differentiation [GO:0071542]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001933; GO:0005041; GO:0005102; GO:0005109; GO:0005576; GO:0005783; GO:0005886; GO:0006469; GO:0007204; GO:0007268; GO:0009986; GO:0014029; GO:0014033; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0031410; GO:0031901; GO:0034392; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043434; GO:0044335; GO:0044340; GO:0045121; GO:0045202; GO:0045787; GO:0045893; GO:0045944; GO:0051091; GO:0060070; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072659; GO:0090118; GO:0090244; GO:0098609; GO:1904928; GO:1904948; GO:1904953; GO:1990851; GO:1990909 6273 XM_044315823.1 11 0 17 4 2 O75581 4.96e-166 Low-density lipoprotein receptor-related protein 6 (LRP-6) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; chemical synaptic transmission [GO:0007268]; dopaminergic neuron differentiation [GO:0071542]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001933; GO:0005041; GO:0005102; GO:0005109; GO:0005576; GO:0005783; GO:0005886; GO:0006469; GO:0007204; GO:0007268; GO:0009986; GO:0014029; GO:0014033; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0031410; GO:0031901; GO:0034392; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043434; GO:0044335; GO:0044340; GO:0045121; GO:0045202; GO:0045787; GO:0045893; GO:0045944; GO:0051091; GO:0060070; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072659; GO:0090118; GO:0090244; GO:0098609; GO:1904928; GO:1904948; GO:1904953; GO:1990851; GO:1990909 6274 XM_044315823.1 11 0 17 4 2 O75581 1.1e-91 Low-density lipoprotein receptor-related protein 6 (LRP-6) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; chemical synaptic transmission [GO:0007268]; dopaminergic neuron differentiation [GO:0071542]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001933; GO:0005041; GO:0005102; GO:0005109; GO:0005576; GO:0005783; GO:0005886; GO:0006469; GO:0007204; GO:0007268; GO:0009986; GO:0014029; GO:0014033; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0031410; GO:0031901; GO:0034392; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043434; GO:0044335; GO:0044340; GO:0045121; GO:0045202; GO:0045787; GO:0045893; GO:0045944; GO:0051091; GO:0060070; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072659; GO:0090118; GO:0090244; GO:0098609; GO:1904928; GO:1904948; GO:1904953; GO:1990851; GO:1990909 6275 XM_044323607.1 1 0 7 35 0 NA NA NA NA NA NA 6276 XM_044323205.1 680 326 453 524 649 NA NA NA NA NA NA 6277 XM_044328449.1 1859 669 589 1230 1066 O15169 1.84e-31 Axin-1 (Axis inhibition protein 1) (hAxin) Homo sapiens (Human) activation of protein kinase activity [GO:0032147]; apoptotic process [GO:0006915]; axial mesoderm formation [GO:0048320]; canonical Wnt signaling pathway [GO:0060070]; cell development [GO:0048468]; cytoplasmic microtubule organization [GO:0031122]; dorsal/ventral axis specification [GO:0009950]; genomic imprinting [GO:0071514]; head development [GO:0060322]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of protein metabolic process [GO:0051248]; negative regulation of transcription elongation by RNA polymerase II [GO:0034244]; nucleocytoplasmic transport [GO:0006913]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; post-anal tail morphogenesis [GO:0036342]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; protein-containing complex assembly [GO:0065003]; sensory perception of sound [GO:0007605] GO:0000209; GO:0001701; GO:0001934; GO:0002039; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0005938; GO:0006913; GO:0006915; GO:0007605; GO:0008013; GO:0008022; GO:0009950; GO:0010800; GO:0015630; GO:0016328; GO:0019899; GO:0019901; GO:0030159; GO:0030511; GO:0030877; GO:0031122; GO:0031398; GO:0031410; GO:0031625; GO:0032147; GO:0032436; GO:0033138; GO:0034244; GO:0035591; GO:0036342; GO:0042802; GO:0042803; GO:0043161; GO:0043507; GO:0043621; GO:0045599; GO:0045732; GO:0045860; GO:0045893; GO:0046330; GO:0046332; GO:0048320; GO:0048468; GO:0048471; GO:0051248; GO:0051443; GO:0060070; GO:0060090; GO:0060322; GO:0065003; GO:0070016; GO:0070411; GO:0070412; GO:0071514; GO:0071944; GO:0090090; GO:1990909; GO:2000060 6278 XM_044328449.1 1859 669 589 1230 1066 O15169 3.76e-24 Axin-1 (Axis inhibition protein 1) (hAxin) Homo sapiens (Human) activation of protein kinase activity [GO:0032147]; apoptotic process [GO:0006915]; axial mesoderm formation [GO:0048320]; canonical Wnt signaling pathway [GO:0060070]; cell development [GO:0048468]; cytoplasmic microtubule organization [GO:0031122]; dorsal/ventral axis specification [GO:0009950]; genomic imprinting [GO:0071514]; head development [GO:0060322]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of protein metabolic process [GO:0051248]; negative regulation of transcription elongation by RNA polymerase II [GO:0034244]; nucleocytoplasmic transport [GO:0006913]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; post-anal tail morphogenesis [GO:0036342]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; protein-containing complex assembly [GO:0065003]; sensory perception of sound [GO:0007605] GO:0000209; GO:0001701; GO:0001934; GO:0002039; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0005938; GO:0006913; GO:0006915; GO:0007605; GO:0008013; GO:0008022; GO:0009950; GO:0010800; GO:0015630; GO:0016328; GO:0019899; GO:0019901; GO:0030159; GO:0030511; GO:0030877; GO:0031122; GO:0031398; GO:0031410; GO:0031625; GO:0032147; GO:0032436; GO:0033138; GO:0034244; GO:0035591; GO:0036342; GO:0042802; GO:0042803; GO:0043161; GO:0043507; GO:0043621; GO:0045599; GO:0045732; GO:0045860; GO:0045893; GO:0046330; GO:0046332; GO:0048320; GO:0048468; GO:0048471; GO:0051248; GO:0051443; GO:0060070; GO:0060090; GO:0060322; GO:0065003; GO:0070016; GO:0070411; GO:0070412; GO:0071514; GO:0071944; GO:0090090; GO:1990909; GO:2000060 6279 XM_044310936.1 17 0 0 0 0 NA NA NA NA NA NA 6280 XR_003823817.2 490 923 160 952 754 NA NA NA NA NA NA 6281 XM_044328372.1 621 465 305 387 435 Q28DX0 1.32e-98 Queuine tRNA-ribosyltransferase accessory subunit 2 (Queuine tRNA-ribosyltransferase domain-containing protein 1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) tRNA-guanine transglycosylation [GO:0101030] GO:0005737; GO:0005739; GO:0005741; GO:0008479; GO:0042803; GO:0046872; GO:0046982; GO:0101030 6282 XM_029334390.2 326 437 274 289 381 NA NA NA NA NA NA 6283 XM_029348269.2 1567 1021 806 1593 1679 NA NA NA NA NA NA 6284 XR_003825374.2 0 0 561 0 0 NA NA NA NA NA NA 6285 XM_029358706.2 267 106 154 152 208 NA NA NA NA NA NA 6286 XR_006391788.1 2 2 10 0 33 NA NA NA NA NA NA 6287 XM_044327777.1 18 0 39 0 11 NA NA NA NA NA NA 6288 XR_003826886.2 77 310 34 112 298 Q01635 4.07e-26 Laminin subunit beta-1 (Laminin beta-1-1 chain) (Laminin-1 subunit beta) (Laminin-10 subunit beta) (Laminin-12 subunit beta) (Laminin-2 subunit beta) (Laminin-6 subunit beta) (Laminin-8 subunit beta) Gallus gallus (Chicken) animal organ morphogenesis [GO:0009887]; basement membrane assembly [GO:0070831]; cell migration [GO:0016477]; negative regulation of cell adhesion [GO:0007162]; neuron projection development [GO:0031175]; positive regulation of cell migration [GO:0030335]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888] GO:0005178; GO:0005201; GO:0005604; GO:0005606; GO:0005607; GO:0005615; GO:0007162; GO:0009887; GO:0009888; GO:0016477; GO:0030335; GO:0031175; GO:0034446; GO:0043256; GO:0043257; GO:0043259; GO:0048471; GO:0070831 6289 XM_029340078.2 27 8 13 32 25 P51049 8.43e-24 Melatonin receptor type 1B-B (Mel-1B-R-B) (Mel1b receptor B) (Melatonin receptor Mel1b Z2.6-4) (zMel1b-1) Danio rerio (Zebrafish) (Brachydanio rerio) G protein-coupled receptor signaling pathway [GO:0007186]; rhythmic process [GO:0048511] GO:0004930; GO:0005886; GO:0007186; GO:0008502; GO:0048511 6290 XM_044324350.1 203 88 126 269 207 NA NA NA NA NA NA 6291 XM_029326580.2 32 46 17 12 242 NA NA NA NA NA NA 6292 XM_029353419.2 6 3 18 3 8 NA NA NA NA NA NA 6293 XM_029355797.2 1912 3634 2314 5189 2398 NA NA NA NA NA NA 6294 XM_044323408.1 11 10 30 11 0 NA NA NA NA NA NA 6295 XM_029338054.2 214 157 92 132 86 NA NA NA NA NA NA 6296 XM_029349580.2 2022 1852 1074 1810 1664 Q9DBS2 3.51e-40 Tumor protein p63-regulated gene 1-like protein (Mossy fiber terminal-associated vertebrate-specific presynaptic protein) (Protein FAM79A) Mus musculus (Mouse) calmodulin dependent kinase signaling pathway [GO:0099004]; negative regulation of synaptic transmission [GO:0050805]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of synaptic vesicle exocytosis [GO:2000300]; synaptic vesicle docking [GO:0016081] GO:0005516; GO:0005737; GO:0008021; GO:0016081; GO:0042802; GO:0044305; GO:0048786; GO:0050805; GO:0051966; GO:0098793; GO:0098850; GO:0098978; GO:0099004; GO:0099171; GO:2000300 6297 XM_029337388.2 2705 1778 1697 2309 2628 Q9EPU0 0 Regulator of nonsense transcripts 1 (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up-frameshift suppressor 1 homolog) (mUpf1) Mus musculus (Mouse) 3'-UTR-mediated mRNA destabilization [GO:0061158]; cell cycle phase transition [GO:0044770]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; DNA duplex unwinding [GO:0032508]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; histone mRNA catabolic process [GO:0071044]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay [GO:0000294]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of mRNA catabolic process [GO:0061014]; regulation of telomere maintenance [GO:0032204]; regulation of translational termination [GO:0006449]; telomere maintenance via semi-conservative replication [GO:0032201] GO:0000184; GO:0000294; GO:0000781; GO:0000785; GO:0000932; GO:0000956; GO:0003682; GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006260; GO:0006281; GO:0006449; GO:0008270; GO:0016887; GO:0032201; GO:0032204; GO:0032508; GO:0035145; GO:0036121; GO:0042162; GO:0044530; GO:0044770; GO:0044877; GO:0048471; GO:0061014; GO:0061158; GO:0071044; GO:0071222; GO:0071347 6298 XM_029323751.2 6 9 32 60 99 Q99315 8.72e-42 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 6299 XM_029323751.2 6 9 32 60 99 Q99315 8.72e-42 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 6300 XM_044326664.1 68 66 65 48 98 Q96AY4 1.28e-166 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6301 XM_044326664.1 68 66 65 48 98 Q96AY4 6.07e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6302 XM_044328113.1 0 0 0 0 7 P97275 0 Alkyldihydroxyacetonephosphate synthase, peroxisomal (Alkyl-DHAP synthase) (EC 2.5.1.26) (Alkylglycerone-phosphate synthase) Cavia porcellus (Guinea pig) ether lipid biosynthetic process [GO:0008611] GO:0005730; GO:0005777; GO:0005778; GO:0008609; GO:0008611; GO:0071949 6303 XR_006396314.1 51 88 69 233 122 NA NA NA NA NA NA 6304 XM_044326411.1 358 191 241 678 311 NA NA NA NA NA NA 6305 XM_044317923.1 97 0 0 0 31 O97490 1.19e-59 Melanotransferrin (Membrane-bound transferrin-like protein p97) (CD antigen CD228) Oryctolagus cuniculus (Rabbit) ion transport [GO:0006811]; iron ion homeostasis [GO:0055072] GO:0005615; GO:0005886; GO:0006811; GO:0046872; GO:0055072 6306 XM_044317923.1 97 0 0 0 31 O97490 5.3e-58 Melanotransferrin (Membrane-bound transferrin-like protein p97) (CD antigen CD228) Oryctolagus cuniculus (Rabbit) ion transport [GO:0006811]; iron ion homeostasis [GO:0055072] GO:0005615; GO:0005886; GO:0006811; GO:0046872; GO:0055072 6307 XM_029333050.2 0 16 121 77 45 B0CQN7 2.72e-31 NADH-cytochrome b5 reductase 1 (EC 1.6.2.2) (Microsomal cytochrome b reductase) Laccaria bicolor (strain S238N-H82 / ATCC MYA-4686) (Bicoloured deceiver) (Laccaria laccata var. bicolor) peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]; tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation [GO:0002926] GO:0002926; GO:0003954; GO:0004128; GO:0005741; GO:0016740; GO:0017183 6308 XM_044311199.1 100 444 156 217 185 NA NA NA NA NA NA 6309 XM_029356930.2 4753 3328 1487 2906 3439 P62257 3.98e-94 Ubiquitin-conjugating enzyme E2 H (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme H) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme H) (UBCH2) (Ubiquitin carrier protein H) (Ubiquitin-conjugating enzyme E2-20K) (Ubiquitin-protein ligase H) Mus musculus (Mouse) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K11-linked ubiquitination [GO:0070979]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000209; GO:0004842; GO:0005524; GO:0005634; GO:0006511; GO:0043161; GO:0061631; GO:0070936; GO:0070979 6310 XM_029334671.2 713 575 450 620 610 Q9CZN7 0 Serine hydroxymethyltransferase, mitochondrial (SHMT) (EC 2.1.2.1) (Glycine hydroxymethyltransferase) (Serine methylase) Mus musculus (Mouse) folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; glycine biosynthetic process from serine [GO:0019264]; glycine metabolic process [GO:0006544]; L-serine biosynthetic process [GO:0006564]; L-serine catabolic process [GO:0006565]; L-serine metabolic process [GO:0006563]; one-carbon metabolic process [GO:0006730]; positive regulation of cell population proliferation [GO:0008284]; protein homotetramerization [GO:0051289]; protein K63-linked deubiquitination [GO:0070536]; protein tetramerization [GO:0051262]; purine nucleobase biosynthetic process [GO:0009113]; regulation of aerobic respiration [GO:1903715]; regulation of mitochondrial translation [GO:0070129]; regulation of oxidative phosphorylation [GO:0002082]; response to type I interferon [GO:0034340]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653] GO:0000900; GO:0002082; GO:0003682; GO:0004372; GO:0005634; GO:0005737; GO:0005739; GO:0005743; GO:0005758; GO:0005759; GO:0005829; GO:0006544; GO:0006545; GO:0006563; GO:0006564; GO:0006565; GO:0006730; GO:0008270; GO:0008284; GO:0008732; GO:0009113; GO:0015630; GO:0016597; GO:0019264; GO:0030170; GO:0034340; GO:0035999; GO:0042645; GO:0042802; GO:0042803; GO:0046653; GO:0046655; GO:0048027; GO:0051262; GO:0051289; GO:0070129; GO:0070536; GO:0070552; GO:0070905; GO:1903715 6311 XM_029350555.2 417 215 349 285 275 NA NA NA NA NA NA 6312 XM_029338511.2 808 96 302 473 76 O08658 1.4e-111 Nuclear pore complex protein Nup88 (88 kDa nucleoporin) (Nucleoporin Nup84) (Nucleoporin Nup88) Rattus norvegicus (Rat) mitotic cell cycle [GO:0000278]; mRNA export from nucleus [GO:0006406]; protein import into nucleus [GO:0006606]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056] GO:0000055; GO:0000056; GO:0000278; GO:0005635; GO:0005643; GO:0005654; GO:0006406; GO:0006606; GO:0017056 6313 XM_044308387.1 293 363 95 825 506 F7B113 0 Sodium/hydrogen exchanger 9 (Na(+)/H(+) exchanger 9) (NHE-9) (Sodium/hydrogen exchanger) (Solute carrier family 9 member 9) Equus caballus (Horse) potassium ion transmembrane transport [GO:0071805]; proton transmembrane transport [GO:1902600]; regulation of intracellular pH [GO:0051453]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725] GO:0005886; GO:0010008; GO:0015385; GO:0015386; GO:0035725; GO:0042803; GO:0051453; GO:0055037; GO:0071805; GO:0098719; GO:1902600 6314 XM_029337086.2 150 121 120 151 148 Q93075 1.68e-81 Putative deoxyribonuclease TATDN2 (EC 3.1.21.-) Homo sapiens (Human) NA GO:0004518; GO:0005654; GO:0046872 6315 XM_029352097.2 38 0 0 0 0 NA NA NA NA NA NA 6316 XM_044323179.1 8 28 2 120 7 Q13591 1.39e-53 Semaphorin-5A (Semaphorin-F) (Sema F) Homo sapiens (Human) axon extension [GO:0048675]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell-cell signaling [GO:0007267]; diencephalon development [GO:0021536]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of cell adhesion [GO:0007162]; negative regulation of endothelial cell apoptotic process [GO:2000352]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; positive chemotaxis [GO:0050918]; positive regulation of actin filament depolymerization [GO:0030836]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein kinase B signaling [GO:0051897]; semaphorin-plexin signaling pathway [GO:0071526]; signal clustering [GO:1990256] GO:0001755; GO:0001938; GO:0002043; GO:0005886; GO:0007155; GO:0007162; GO:0007267; GO:0007399; GO:0007411; GO:0007413; GO:0016020; GO:0021536; GO:0030215; GO:0030335; GO:0030836; GO:0035373; GO:0043395; GO:0045499; GO:0045545; GO:0045766; GO:0048675; GO:0048842; GO:0048843; GO:0050918; GO:0051897; GO:0060326; GO:0070062; GO:0071526; GO:0090263; GO:1990256; GO:2000352; GO:2001028 6317 XM_044318979.1 193 424 177 157 490 Q3ZCC3 3.28e-93 TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6) Bos taurus (Bovine) activation of NF-kappaB-inducing kinase activity [GO:0007250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; bone resorption [GO:0045453]; cellular response to DNA damage stimulus [GO:0006974]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; in utero embryonic development [GO:0001701]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-17-mediated signaling pathway [GO:0097400]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin production [GO:0002637]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000122; GO:0001503; GO:0001701; GO:0001843; GO:0002637; GO:0002726; GO:0004842; GO:0005164; GO:0005634; GO:0005811; GO:0005829; GO:0005938; GO:0006974; GO:0007249; GO:0007250; GO:0008270; GO:0009898; GO:0019886; GO:0030316; GO:0031435; GO:0031624; GO:0031625; GO:0031663; GO:0031666; GO:0031996; GO:0032735; GO:0032743; GO:0032755; GO:0032813; GO:0033209; GO:0035631; GO:0042088; GO:0042102; GO:0042475; GO:0042802; GO:0042826; GO:0042981; GO:0043011; GO:0043122; GO:0043123; GO:0043422; GO:0043507; GO:0045453; GO:0045672; GO:0045944; GO:0046330; GO:0047485; GO:0048471; GO:0050852; GO:0051092; GO:0051865; GO:0061630; GO:0070498; GO:0070534; GO:0097400; GO:1901224; GO:1904996; GO:2000679 6318 XM_029343088.2 368 461 187 140 91 O43399 8.24e-21 Tumor protein D54 (hD54) (Tumor protein D52-like 2) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; regulation of cell population proliferation [GO:0042127] GO:0003723; GO:0005737; GO:0005975; GO:0042127; GO:0042803; GO:0048471 6319 XM_044326811.1 72 21 16 43 59 NA NA NA NA NA NA 6320 XM_029345796.2 300 343 135 533 229 Q0DXS3 6.97e-137 Probable RNA-dependent RNA polymerase 1 (OsRDR1) (EC 2.7.7.48) Oryza sativa subsp. japonica (Rice) positive regulation of post-transcriptional gene silencing [GO:0060148]; response to salicylic acid [GO:0009751]; response to virus [GO:0009615]; siRNA processing [GO:0030422]; wax biosynthetic process [GO:0010025] GO:0003723; GO:0003968; GO:0009615; GO:0009751; GO:0010025; GO:0030422; GO:0031380; GO:0060148 6321 XM_029353153.2 2315 1340 1305 1936 1969 O75643 0 U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.4.13) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog) (U5 snRNP-specific 200 kDa protein) (U5-200KD) Homo sapiens (Human) cis assembly of pre-catalytic spliceosome [GO:0000354]; mRNA splicing, via spliceosome [GO:0000398]; osteoblast differentiation [GO:0001649]; spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) [GO:0000388] GO:0000354; GO:0000388; GO:0000398; GO:0001649; GO:0003723; GO:0003724; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0005681; GO:0005682; GO:0016020; GO:0016887; GO:0042802; GO:0046540; GO:0071005; GO:0071006; GO:0071013 6322 XM_029336071.2 136 44 33 10 8 Q8WYK1 1.08e-34 Contactin-associated protein-like 5 (Cell recognition molecule Caspr5) Homo sapiens (Human) cell adhesion [GO:0007155] GO:0007155; GO:0016020 6323 XR_006391426.1 11 26 7 19 6 NA NA NA NA NA NA 6324 XM_044307083.1 202 442 507 682 759 P31669 0 Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 1) (ARTD1) (DNA ADP-ribosyltransferase PARP1) (EC 2.4.2.-) (NAD(+) ADP-ribosyltransferase 1) (ADPRT 1) (Poly[ADP-ribose] synthase 1) (Protein poly-ADP-ribosyltransferase PARP1) (EC 2.4.2.-) Xenopus laevis (African clawed frog) ATP generation from poly-ADP-D-ribose [GO:1990966]; DNA ADP-ribosylation [GO:0030592]; DNA repair [GO:0006281]; innate immune response [GO:0045087]; negative regulation of innate immune response [GO:0045824]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; protein auto-ADP-ribosylation [GO:0070213]; protein poly-ADP-ribosylation [GO:0070212]; replication fork reversal [GO:0071932] GO:0000122; GO:0000785; GO:0003684; GO:0003950; GO:0005730; GO:0005829; GO:0006281; GO:0008270; GO:0016779; GO:0030592; GO:0031491; GO:0035861; GO:0042803; GO:0043596; GO:0045087; GO:0045824; GO:0051287; GO:0070212; GO:0070213; GO:0071932; GO:0140805; GO:0140806; GO:0140807; GO:0140808; GO:0140815; GO:1905168; GO:1990404; GO:1990966 6325 XM_029348938.2 252 5 0 597 70 O54852 6.28e-102 Potassium voltage-gated channel subfamily H member 7 (Ether-a-go-go-related gene potassium channel 3) (ERG-3) (Eag-related protein 3) (Ether-a-go-go-related protein 3) (Voltage-gated potassium channel subunit Kv11.3) Rattus norvegicus (Rat) circadian rhythm [GO:0007623]; membrane repolarization during action potential [GO:0086011]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391] GO:0005242; GO:0005249; GO:0005267; GO:0005886; GO:0006813; GO:0007623; GO:0034765; GO:0042391; GO:0044877; GO:0071805; GO:0086011 6326 XM_044328242.1 93 26 53 47 212 NA NA NA NA NA NA 6327 XM_029337542.2 30 23 149 42 111 Q9UBX3 2.68e-90 Mitochondrial dicarboxylate carrier (DIC) (Solute carrier family 25 member 10) Homo sapiens (Human) dicarboxylic acid transport [GO:0006835]; gluconeogenesis [GO:0006094]; ion transport [GO:0006811]; lipid transport [GO:0006869]; malate transmembrane transport [GO:0071423]; mitochondrial transport [GO:0006839]; oxaloacetate transport [GO:0015729]; phosphate ion transmembrane transport [GO:0035435]; succinate transmembrane transport [GO:0071422]; sulfate transport [GO:0008272]; sulfide oxidation, using sulfide:quinone oxidoreductase [GO:0070221]; thiosulfate transport [GO:0015709] GO:0005310; GO:0005634; GO:0005654; GO:0005739; GO:0005743; GO:0006094; GO:0006811; GO:0006835; GO:0006839; GO:0006869; GO:0008272; GO:0015114; GO:0015116; GO:0015117; GO:0015131; GO:0015140; GO:0015141; GO:0015297; GO:0015709; GO:0015729; GO:0022857; GO:0035435; GO:0070221; GO:0071422; GO:0071423 6328 XM_044311213.1 65 39 39 2 187 NA NA NA NA NA NA 6329 XM_044313155.1 39 1 1 2 0 A2AJ76 4.19e-72 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 6330 XM_044313155.1 39 1 1 2 0 A2AJ76 1.26e-63 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 6331 XM_044313155.1 39 1 1 2 0 A2AJ76 2.9e-63 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 6332 XM_044313155.1 39 1 1 2 0 A2AJ76 8.07e-62 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 6333 XM_044313155.1 39 1 1 2 0 A2AJ76 2.95e-58 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 6334 XM_044313155.1 39 1 1 2 0 A2AJ76 4.01e-55 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 6335 XM_044313155.1 39 1 1 2 0 A2AJ76 8.8e-50 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 6336 XM_044313155.1 39 1 1 2 0 A2AJ76 1.04e-49 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 6337 XM_044313155.1 39 1 1 2 0 A2AJ76 4.4e-47 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 6338 XM_044313155.1 39 1 1 2 0 A2AJ76 2.32e-46 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 6339 XM_044313155.1 39 1 1 2 0 A2AJ76 2.36e-46 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 6340 XM_044313155.1 39 1 1 2 0 A2AJ76 1.78e-43 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 6341 XM_044313155.1 39 1 1 2 0 A2AJ76 2.17e-43 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 6342 XM_044313155.1 39 1 1 2 0 A2AJ76 2.89e-34 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 6343 XM_044313155.1 39 1 1 2 0 A2AJ76 2.21e-27 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 6344 XM_029329086.2 8 30 352 779 22 Q9UBF6 1.07e-46 RING-box protein 2 (Rbx2) (CKII beta-binding protein 1) (CKBBP1) (RING finger protein 7) (Regulator of cullins 2) (Sensitive to apoptosis gene protein) Homo sapiens (Human) post-translational protein modification [GO:0043687]; protein neddylation [GO:0045116]; protein ubiquitination [GO:0016567]; response to redox state [GO:0051775]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0005507; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006511; GO:0008270; GO:0016567; GO:0019788; GO:0031461; GO:0031466; GO:0043687; GO:0045116; GO:0051775; GO:0061630; GO:0061663; GO:0097602 6345 XM_029323600.2 202 154 203 146 467 Q86XL3 1.13e-72 Ankyrin repeat and LEM domain-containing protein 2 (LEM domain-containing protein 4) Homo sapiens (Human) cell division [GO:0051301]; central nervous system development [GO:0007417]; mitotic nuclear membrane reassembly [GO:0007084]; negative regulation of apoptotic process [GO:0043066]; negative regulation of phosphorylation [GO:0042326]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of catalytic activity [GO:0050790] GO:0005783; GO:0005789; GO:0007084; GO:0007417; GO:0016020; GO:0019888; GO:0035307; GO:0042326; GO:0043066; GO:0050790; GO:0051301; GO:0051721 6346 XM_044319899.1 247 58 144 272 317 O42231 2.17e-91 Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) Chelon auratus (Golden grey mullet) (Liza aurata) NA GO:0005506; GO:0005789; GO:0020037; GO:0070330 6347 XM_044324862.1 252 94 1 157 12 NA NA NA NA NA NA 6348 XM_044314568.1 61 32 15 24 53 Q94K49 1e-36 Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1 (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) epigenetic regulation of gene expression [GO:0040029] GO:0003682; GO:0004518; GO:0005634; GO:0035098; GO:0035102; GO:0040029; GO:0046872 6349 XM_029335134.2 2225 2160 1200 1895 1590 Q70CQ4 1.76e-165 Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.4.19.12) (Deubiquitinating enzyme 31) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) Homo sapiens (Human) protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004843; GO:0005634; GO:0006511; GO:0016579 6350 XM_044325715.1 263 216 184 230 403 NA NA NA NA NA NA 6351 XM_029329630.2 7 23 4 19 14 NA NA NA NA NA NA 6352 XM_029342454.2 0 0 5 2 9 Q96KE9 1.89e-55 BTB/POZ domain-containing protein 6 (Lens BTB domain protein) Homo sapiens (Human) neurogenesis [GO:0022008] GO:0005829; GO:0022008 6353 XM_029346369.2 1205 769 775 822 1033 Q3TT38 9e-88 Protein ILRUN Mus musculus (Mouse) innate immune response [GO:0045087]; macroautophagy [GO:0016236]; negative regulation of defense response to virus [GO:0050687]; negative regulation of DNA binding [GO:0043392]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type I interferon production [GO:0032480] GO:0000407; GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0016236; GO:0016607; GO:0032480; GO:0032720; GO:0043130; GO:0043392; GO:0045087; GO:0050687; GO:1900181 6354 XR_006397182.1 527 173 392 580 456 NA NA NA NA NA NA 6355 XM_029338765.2 1015 883 444 702 600 P42325 1.08e-110 Neurocalcin homolog (DrosNCa) Drosophila melanogaster (Fruit fly) negative regulation of neuronal signal transduction [GO:1902848]; positive regulation of circadian sleep/wake cycle, sleep [GO:0045938] GO:0005509; GO:0045938; GO:1902848 6356 XM_029334975.2 0 0 11 0 40 NA NA NA NA NA NA 6357 XM_029351713.2 1110 892 795 1627 1439 NA NA NA NA NA NA 6358 XM_029358530.2 9 1 0 0 9 NA NA NA NA NA NA 6359 XM_044320284.1 71 68 130 130 240 NA NA NA NA NA NA 6360 XM_029332714.2 431 385 262 340 406 Q9QZ08 5.02e-87 N-acetyl-D-glucosamine kinase (N-acetylglucosamine kinase) (EC 2.7.1.59) (GlcNAc kinase) Mus musculus (Mouse) N-acetylglucosamine metabolic process [GO:0006044]; N-acetylneuraminate catabolic process [GO:0019262] GO:0005524; GO:0006044; GO:0009384; GO:0019262; GO:0045127 6361 XM_029344893.2 1558 1639 1291 836 1098 Q9UQF2 7.29e-56 C-Jun-amino-terminal kinase-interacting protein 1 (JIP-1) (JNK-interacting protein 1) (Islet-brain 1) (IB-1) (JNK MAP kinase scaffold protein 1) (Mitogen-activated protein kinase 8-interacting protein 1) Homo sapiens (Human) JUN phosphorylation [GO:0007258]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of JUN kinase activity [GO:0043508]; positive regulation of JNK cascade [GO:0046330]; regulation of CD8-positive, alpha-beta T cell proliferation [GO:2000564]; regulation of DNA-templated transcription [GO:0006355]; regulation of JNK cascade [GO:0046328]; vesicle-mediated transport [GO:0016192] GO:0004860; GO:0005078; GO:0005634; GO:0005737; GO:0005789; GO:0005829; GO:0005886; GO:0006355; GO:0007258; GO:0016192; GO:0019894; GO:0019901; GO:0030425; GO:0031966; GO:0043025; GO:0043508; GO:0044302; GO:0045202; GO:0046328; GO:0046330; GO:0048471; GO:2000564; GO:2001243 6362 XM_044314879.1 5 21 0 35 6 NA NA NA NA NA NA 6363 XM_044307154.1 135 84 29 46 612 NA NA NA NA NA NA 6364 XM_044309428.1 969 378 436 562 789 NA NA NA NA NA NA 6365 XM_029343740.2 0 0 0 20 0 NA NA NA NA NA NA 6366 XM_029327000.2 85 56 44 82 98 NA NA NA NA NA NA 6367 XM_044316886.1 42630 56013 27917 43274 39676 NA NA NA NA NA NA 6368 XR_006395491.1 3548 1228 149 2376 1372 NA NA NA NA NA NA 6369 XM_029342213.2 0 297 282 368 687 NA NA NA NA NA NA 6370 XM_029333909.2 262 60 18 77 13 NA NA NA NA NA NA 6371 XM_044320573.1 98 0 0 0 0 NA NA NA NA NA NA 6372 XR_006396075.1 187 83 90 239 183 NA NA NA NA NA NA 6373 XM_044308322.1 56 0 38 83 7 Q9NUV9 3.3e-23 GTPase IMAP family member 4 (Immunity-associated nucleotide 1 protein) (IAN-1) (hIAN1) (Immunity-associated protein 4) Homo sapiens (Human) NA GO:0005525; GO:0005829; GO:0043231 6374 XM_044320460.1 29 391 22 59 86 NA NA NA NA NA NA 6375 XM_029331466.2 24 21 25 24 105 NA NA NA NA NA NA 6376 XM_044329234.1 814 647 517 849 1149 NA NA NA NA NA NA 6377 XR_006396570.1 3 0 50 45 38 NA NA NA NA NA NA 6378 XM_029345223.2 119 50 45 41 163 Q9H3D4 1.24e-37 Tumor protein 63 (p63) (Chronic ulcerative stomatitis protein) (CUSP) (Keratinocyte transcription factor KET) (Transformation-related protein 63) (TP63) (Tumor protein p73-like) (p73L) (p40) (p51) Homo sapiens (Human) apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular senescence [GO:0090398]; chromatin remodeling [GO:0006338]; cloacal septation [GO:0060197]; cranial skeletal system development [GO:1904888]; ectoderm and mesoderm interaction [GO:0007499]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; epidermal cell division [GO:0010481]; epithelial cell development [GO:0002064]; establishment of planar polarity [GO:0001736]; establishment of skin barrier [GO:0061436]; female genitalia morphogenesis [GO:0048807]; hair follicle morphogenesis [GO:0031069]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; keratinocyte differentiation [GO:0030216]; keratinocyte proliferation [GO:0043616]; multicellular organism aging [GO:0010259]; negative regulation of cellular senescence [GO:2000773]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of keratinocyte differentiation [GO:0045617]; negative regulation of mesoderm development [GO:2000381]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron apoptotic process [GO:0051402]; Notch signaling pathway [GO:0007219]; odontogenesis of dentin-containing tooth [GO:0042475]; polarized epithelial cell differentiation [GO:0030859]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cell cycle G1/S phase transition [GO:1902808]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of fibroblast apoptotic process [GO:2000271]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of somatic stem cell population maintenance [GO:1904674]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; prostatic bud formation [GO:0060513]; protein tetramerization [GO:0051262]; proximal/distal pattern formation [GO:0009954]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of epidermal cell division [GO:0010482]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal system development [GO:0001501]; skin morphogenesis [GO:0043589]; spermatogenesis [GO:0007283]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; stem cell proliferation [GO:0072089]; sympathetic nervous system development [GO:0048485]; transcription by RNA polymerase II [GO:0006366] GO:0000122; GO:0000785; GO:0000977; GO:0000978; GO:0000981; GO:0001228; GO:0001501; GO:0001736; GO:0002039; GO:0002064; GO:0003677; GO:0003682; GO:0003684; GO:0003700; GO:0005634; GO:0005654; GO:0005737; GO:0005791; GO:0006338; GO:0006357; GO:0006366; GO:0006915; GO:0006974; GO:0007219; GO:0007283; GO:0007499; GO:0009954; GO:0010259; GO:0010481; GO:0010482; GO:0010838; GO:0030216; GO:0030425; GO:0030859; GO:0031069; GO:0032991; GO:0033147; GO:0035115; GO:0035116; GO:0036342; GO:0042475; GO:0042771; GO:0042802; GO:0043281; GO:0043589; GO:0043616; GO:0045617; GO:0045669; GO:0045747; GO:0045892; GO:0045893; GO:0045944; GO:0046872; GO:0048485; GO:0048807; GO:0050699; GO:0051262; GO:0051402; GO:0060197; GO:0060513; GO:0060529; GO:0061436; GO:0072089; GO:0090398; GO:0097371; GO:1902808; GO:1904674; GO:1904888; GO:2000271; GO:2000381; GO:2000648; GO:2000773; GO:2001235 6379 XR_006392374.1 9 2 49 10 123 NA NA NA NA NA NA 6380 XM_029337117.2 2406 1745 1415 2750 2229 NA NA NA NA NA NA 6381 XM_029356564.2 874 570 504 744 1004 Q5ZJ85 0 U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3) Gallus gallus (Chicken) mRNA splicing, via spliceosome [GO:0000398]; spliceosomal tri-snRNP complex assembly [GO:0000244] GO:0000244; GO:0000398; GO:0005634; GO:0005681; GO:0016607; GO:0046540 6382 XM_029346574.2 681 560 361 966 1111 NA NA NA NA NA NA 6383 XM_044308440.1 1077 775 480 775 925 A5HK05 0 Amyloid protein-binding protein 2 (Amyloid beta precursor protein-binding protein 2) (APP-BP2) Rattus norvegicus (Rat) intracellular protein transport [GO:0006886]; intracellular transport [GO:0046907]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567] GO:0005654; GO:0005874; GO:0006886; GO:0016567; GO:0030659; GO:0031462; GO:0043161; GO:0046907; GO:1990756 6384 XM_029327097.2 51 38 31 113 34 NA NA NA NA NA NA 6385 XM_044308227.1 321 326 61 257 256 NA NA NA NA NA NA 6386 XM_029335966.2 0 0 24 0 0 NA NA NA NA NA NA 6387 XM_029334606.2 2 7 6 1 34 NA NA NA NA NA NA 6388 XR_006397991.1 0 209 0 0 0 NA NA NA NA NA NA 6389 XR_006395849.1 69 51 44 3 8 NA NA NA NA NA NA 6390 XM_044318926.1 0 0 51 1 60 NA NA NA NA NA NA 6391 XM_029350894.2 1326 1350 830 570 679 Q5U3V7 1.32e-91 Solute carrier family 25 member 43 Danio rerio (Zebrafish) (Brachydanio rerio) transmembrane transport [GO:0055085] GO:0005743; GO:0055085 6392 XM_029344950.2 21 42 48 39 128 NA NA NA NA NA NA 6393 XM_044310959.1 48 126 84 30 290 Q9M2U3 6.35e-30 Protein ALP1-like (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) NA GO:0000118; GO:0004518; GO:0046872 6394 XM_029342792.2 13 0 1 3 3 NA NA NA NA NA NA 6395 XM_044321828.1 0 0 0 0 69 P18505 6.67e-86 Gamma-aminobutyric acid receptor subunit beta-1 (GABA(A) receptor subunit beta-1) Homo sapiens (Human) cellular response to histamine [GO:0071420]; central nervous system neuron development [GO:0021954]; chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid signaling pathway [GO:0007214]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; nervous system process [GO:0050877]; ovulation cycle [GO:0042698]; regulation of membrane potential [GO:0042391]; response to progesterone [GO:0032570]; response to toxic substance [GO:0009636]; signal transduction [GO:0007165] GO:0004890; GO:0005231; GO:0005635; GO:0005737; GO:0005886; GO:0006811; GO:0007165; GO:0007214; GO:0007268; GO:0009636; GO:0015276; GO:0021954; GO:0022851; GO:0030425; GO:0030594; GO:0032570; GO:0034220; GO:0034707; GO:0042391; GO:0042698; GO:0043005; GO:0045202; GO:0048787; GO:0050811; GO:0050877; GO:0071420; GO:0098685; GO:0098982; GO:0099507; GO:0099634; GO:0150047; GO:1902476; GO:1902711; GO:1904315 6396 XM_029339805.2 0 0 211 0 0 NA NA NA NA NA NA 6397 XM_044312307.1 8 0 3 0 0 NA NA NA NA NA NA 6398 XM_029336032.2 81 113 56 238 133 NA NA NA NA NA NA 6399 XM_044322029.1 0 5 275 645 769 Q5SW96 4.68e-25 Low density lipoprotein receptor adapter protein 1 (Autosomal recessive hypercholesterolemia protein) Homo sapiens (Human) amyloid precursor protein metabolic process [GO:0042982]; cellular response to cytokine stimulus [GO:0071345]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; cholesterol transport [GO:0030301]; low-density lipoprotein particle clearance [GO:0034383]; positive regulation of cholesterol metabolic process [GO:0090205]; positive regulation of low-density lipoprotein particle clearance [GO:1905581]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905602]; positive regulation of vascular associated smooth muscle cell proliferation [GO:1904707]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of protein binding [GO:0043393]; regulation of protein localization to plasma membrane [GO:1903076] GO:0001540; GO:0001784; GO:0005546; GO:0005769; GO:0005829; GO:0005883; GO:0005886; GO:0006898; GO:0008203; GO:0009898; GO:0009925; GO:0030159; GO:0030276; GO:0030301; GO:0030424; GO:0030669; GO:0031623; GO:0034383; GO:0035591; GO:0035612; GO:0035615; GO:0035650; GO:0042632; GO:0042982; GO:0043393; GO:0048260; GO:0050750; GO:0055037; GO:0071345; GO:0090118; GO:0090205; GO:1903076; GO:1904707; GO:1905581; GO:1905602 6400 XM_029329096.2 1022 0 31 292 284 NA NA NA NA NA NA 6401 XM_044310603.1 2 4 0 5 7 NA NA NA NA NA NA 6402 XM_029356154.2 0 7 7 5 13 NA NA NA NA NA NA 6403 XR_006393227.1 41 0 8 60 0 NA NA NA NA NA NA 6404 XR_006396834.1 0 0 0 23 0 NA NA NA NA NA NA 6405 XM_029333640.2 116 118 18 16 0 Q8WV37 2.41e-48 Zinc finger protein 480 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0046872 6406 XM_029333640.2 116 118 18 16 0 Q8WV37 3.72e-41 Zinc finger protein 480 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0046872 6407 XM_029333640.2 116 118 18 16 0 Q8WV37 2.02e-40 Zinc finger protein 480 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0046872 6408 XM_029333640.2 116 118 18 16 0 Q8WV37 3.53e-40 Zinc finger protein 480 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0046872 6409 XM_029333640.2 116 118 18 16 0 Q8WV37 6.62e-39 Zinc finger protein 480 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0046872 6410 XM_029333640.2 116 118 18 16 0 Q8WV37 3.87e-34 Zinc finger protein 480 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0046872 6411 XM_029333640.2 116 118 18 16 0 Q8WV37 4.63e-33 Zinc finger protein 480 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0046872 6412 XM_029333640.2 116 118 18 16 0 Q8WV37 1.84e-26 Zinc finger protein 480 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0046872 6413 XR_003827763.2 21 44 82 67 24 NA NA NA NA NA NA 6414 XM_029338143.2 1277 2199 1262 1580 1387 NA NA NA NA NA NA 6415 XM_029324594.2 374 148 39 352 265 NA NA NA NA NA NA 6416 XM_029338062.2 2173 1393 1332 2508 2086 NA NA NA NA NA NA 6417 XM_029337057.2 488 455 285 1340 1307 Q8IVH2 2.78e-74 Forkhead box protein P4 (Fork head-related protein-like A) Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000785; GO:0000978; GO:0000981; GO:0001227; GO:0005634; GO:0006357; GO:0046872 6418 XM_044307918.1 5 5 1 15 3 NA NA NA NA NA NA 6419 XR_006391819.1 10 0 0 36 0 NA NA NA NA NA NA 6420 XM_029335298.2 1381 802 453 334 971 Q3UHG7 1.59e-115 DENN domain-containing protein 11 (DENND11) (Protein LCHN) Mus musculus (Mouse) NA GO:0005085; GO:0005737 6421 XM_029356645.2 11 17 10 27 32 NA NA NA NA NA NA 6422 XM_029342117.2 78 80 61 233 241 P21804 3.78e-80 Fibroblast growth factor receptor 1 (FGFR-1) (bFGF-R-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (Tyrosine kinase receptor CEK1) Gallus gallus (Chicken) epicardial cell to mesenchymal cell transition [GO:0003347]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phospholipase C activity [GO:0010863]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0003347; GO:0004714; GO:0005007; GO:0005524; GO:0005634; GO:0005829; GO:0005886; GO:0007169; GO:0008201; GO:0008284; GO:0010863; GO:0017134; GO:0018108; GO:0031410; GO:0033674; GO:0043235; GO:0043406; GO:0045597; GO:0045893 6423 XR_006392063.1 9 0 14 0 0 NA NA NA NA NA NA 6424 XM_044312634.1 15 5 5 23 62 NA NA NA NA NA NA 6425 XR_006392404.1 1483 1367 796 1660 781 NA NA NA NA NA NA 6426 XR_006393506.1 0 0 0 6 3 NA NA NA NA NA NA 6427 XM_029353113.2 0 64 0 0 33 P49582 5.98e-78 Neuronal acetylcholine receptor subunit alpha-7 Mus musculus (Mouse) acetylcholine receptor signaling pathway [GO:0095500]; associative learning [GO:0008306]; B cell activation [GO:0042113]; behavioral response to ethanol [GO:0048149]; behavioral response to nicotine [GO:0035095]; calcium ion transport [GO:0006816]; chemical synaptic transmission [GO:0007268]; dendrite arborization [GO:0140059]; dendritic spine organization [GO:0097061]; endocytosis [GO:0006897]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; generation of ovulation cycle rhythm [GO:0060112]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; learning or memory [GO:0007611]; membrane depolarization [GO:0051899]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; modulation of excitatory postsynaptic potential [GO:0098815]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of tumor necrosis factor production [GO:0032720]; nervous system process [GO:0050877]; neuronal action potential [GO:0019228]; ovulation cycle [GO:0042698]; positive regulation of acetylcholine biosynthetic process [GO:1905923]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of CoA-transferase activity [GO:1905920]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure [GO:0001988]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of amyloid fibril formation [GO:1905906]; regulation of inflammatory response [GO:0050727]; regulation of membrane potential [GO:0042391]; regulation of neuron death [GO:1901214]; regulation of nitric oxide metabolic process [GO:0080164]; regulation of norepinephrine secretion [GO:0014061]; regulation of response to drug [GO:2001023]; regulation of synapse structural plasticity [GO:0051823]; regulation of synaptic transmission, cholinergic [GO:0032222]; regulation of synaptic transmission, dopaminergic [GO:0032225]; response to acetylcholine [GO:1905144]; response to amyloid-beta [GO:1904645]; response to cold [GO:0009409]; response to ethanol [GO:0045471]; response to food [GO:0032094]; response to nicotine [GO:0035094]; sensory processing [GO:0050893]; signal transduction [GO:0007165]; synapse organization [GO:0050808]; synaptic transmission, cholinergic [GO:0007271]; T cell activation [GO:0042110] GO:0001540; GO:0001933; GO:0001934; GO:0001988; GO:0005216; GO:0005231; GO:0005737; GO:0005886; GO:0005892; GO:0006811; GO:0006816; GO:0006897; GO:0007165; GO:0007268; GO:0007271; GO:0007611; GO:0007613; GO:0008179; GO:0008306; GO:0009409; GO:0009897; GO:0010628; GO:0014061; GO:0014069; GO:0015464; GO:0015643; GO:0016020; GO:0016324; GO:0017081; GO:0019228; GO:0019901; GO:0022848; GO:0030317; GO:0030424; GO:0030425; GO:0030426; GO:0030594; GO:0030673; GO:0032094; GO:0032222; GO:0032225; GO:0032279; GO:0032691; GO:0032715; GO:0032720; GO:0033138; GO:0034220; GO:0035094; GO:0035095; GO:0042110; GO:0042113; GO:0042166; GO:0042391; GO:0042698; GO:0042734; GO:0042803; GO:0043005; GO:0043025; GO:0043197; GO:0043198; GO:0044853; GO:0045121; GO:0045202; GO:0045211; GO:0045471; GO:0048149; GO:0050727; GO:0050728; GO:0050804; GO:0050808; GO:0050877; GO:0050893; GO:0051117; GO:0051247; GO:0051649; GO:0051823; GO:0051899; GO:0060112; GO:0070373; GO:0070374; GO:0080164; GO:0095500; GO:0097061; GO:0097110; GO:0098690; GO:0098793; GO:0098815; GO:0098897; GO:0098981; GO:0099171; GO:0099634; GO:0140059; GO:1900273; GO:1901214; GO:1902004; GO:1904315; GO:1904645; GO:1905144; GO:1905906; GO:1905920; GO:1905923; GO:2000463; GO:2001023 6428 XM_029323979.2 288 172 137 128 204 Q9BV90 2.05e-44 U11/U12 small nuclear ribonucleoprotein 25 kDa protein (U11/U12 snRNP 25 kDa protein) (U11/U12-25K) (Minus-99 protein) Homo sapiens (Human) mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380] GO:0000398; GO:0005634; GO:0005654; GO:0005689; GO:0005829; GO:0008380; GO:0045171 6429 XM_029342994.2 427 217 0 2 2071 Q9JID6 0 Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3) (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain acyl-CoA synthetase 1) (LACS 1) (Palmitoyl-CoA ligase) (Phytanate--CoA ligase) (EC 6.2.1.24) Cavia porcellus (Guinea pig) long-chain fatty acid metabolic process [GO:0001676]; very long-chain fatty acid metabolic process [GO:0000038] GO:0000038; GO:0001676; GO:0004467; GO:0005524; GO:0005741; GO:0005778; GO:0005783; GO:0005789; GO:0047676; GO:0050197; GO:0070251 6430 XR_006392109.1 7 0 7 1 0 NA NA NA NA NA NA 6431 XM_044319190.1 51 59 82 47 152 Q9MYW0 4.68e-48 Short transient receptor potential channel 6 (TrpC6) Bos taurus (Bovine) calcium ion transmembrane transport [GO:0070588]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of ion transmembrane transporter activity [GO:0032414]; regulation of cytosolic calcium ion concentration [GO:0051480]; single fertilization [GO:0007338] GO:0005261; GO:0005737; GO:0005886; GO:0007204; GO:0007338; GO:0015279; GO:0032414; GO:0034703; GO:0036057; GO:0042803; GO:0051480; GO:0051928; GO:0070588; GO:0070679 6432 XM_029338170.2 1557 1142 1177 1828 1806 Q9VK45 0 Serine/threonine-protein kinase Tor (EC 2.7.11.1) (Target of rapamycin) Drosophila melanogaster (Fruit fly) apical protein localization [GO:0045176]; autophagy [GO:0006914]; cellular response to nutrient [GO:0031670]; dendrite morphogenesis [GO:0048813]; determination of adult lifespan [GO:0008340]; endocytic recycling [GO:0032456]; germarium-derived cystoblast division [GO:0048142]; germline cell cycle switching, mitotic to meiotic cell cycle [GO:0051729]; gonad development [GO:0008406]; insulin receptor signaling pathway [GO:0008286]; lamellocyte differentiation [GO:0035171]; larval midgut cell programmed cell death [GO:0035096]; multicellular organism growth [GO:0035264]; negative regulation of apoptotic process [GO:0043066]; negative regulation of macroautophagy [GO:0016242]; negative regulation of proteasomal protein catabolic process [GO:1901799]; positive regulation of axon guidance [GO:1902669]; positive regulation of cell size [GO:0045793]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of ribosome biogenesis [GO:0090070]; positive regulation of synaptic assembly at neuromuscular junction [GO:0045887]; positive regulation of transcription by RNA polymerase III [GO:0045945]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; regulation of cell growth [GO:0001558]; regulation of reactive oxygen species metabolic process [GO:2000377]; regulation of response to drug [GO:2001023]; regulation of terminal button organization [GO:2000331]; terminal branching, open tracheal system [GO:0007430]; TOR signaling [GO:0031929]; TORC1 signaling [GO:0038202]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] GO:0001558; GO:0001934; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0006468; GO:0006914; GO:0007430; GO:0008286; GO:0008340; GO:0008406; GO:0016242; GO:0031490; GO:0031670; GO:0031929; GO:0031931; GO:0031932; GO:0032456; GO:0035096; GO:0035171; GO:0035264; GO:0038202; GO:0043066; GO:0043621; GO:0044877; GO:0045176; GO:0045793; GO:0045887; GO:0045945; GO:0046628; GO:0048010; GO:0048142; GO:0048813; GO:0051729; GO:0051897; GO:0090070; GO:0090303; GO:0106310; GO:1901799; GO:1902669; GO:2000331; GO:2000377; GO:2001023 6433 XR_006396671.1 14 0 1 0 0 NA NA NA NA NA NA 6434 XR_003824675.2 179 755 302 306 201 NA NA NA NA NA NA 6435 XM_029332773.2 6308 5410 2956 5681 5198 P18395 0 Cold shock domain-containing protein E1 (Protein UNR) Rattus norvegicus (Rat) CRD-mediated mRNA stabilization [GO:0070934]; IRES-dependent viral translational initiation [GO:0075522]; negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900152]; nuclear-transcribed mRNA catabolic process, no-go decay [GO:0070966]; positive regulation of cytoplasmic translation [GO:2000767]; stress granule assembly [GO:0034063] GO:0000932; GO:0005794; GO:0005886; GO:0010494; GO:0034063; GO:0035613; GO:0070934; GO:0070937; GO:0070966; GO:0075522; GO:0106002; GO:1900152; GO:2000767 6436 XM_029332773.2 6308 5410 2956 5681 5198 P18395 8.27e-53 Cold shock domain-containing protein E1 (Protein UNR) Rattus norvegicus (Rat) CRD-mediated mRNA stabilization [GO:0070934]; IRES-dependent viral translational initiation [GO:0075522]; negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900152]; nuclear-transcribed mRNA catabolic process, no-go decay [GO:0070966]; positive regulation of cytoplasmic translation [GO:2000767]; stress granule assembly [GO:0034063] GO:0000932; GO:0005794; GO:0005886; GO:0010494; GO:0034063; GO:0035613; GO:0070934; GO:0070937; GO:0070966; GO:0075522; GO:0106002; GO:1900152; GO:2000767 6437 XM_029349179.2 2518 765 608 1080 758 Q8N3Y7 2.26e-78 Epidermal retinol dehydrogenase 2 (EPHD-2) (RDH-E2) (EC 1.1.1.105) (Retinal short-chain dehydrogenase reductase 2) (retSDR2) (Short-chain dehydrogenase/reductase family 16C member 5) Homo sapiens (Human) keratinocyte proliferation [GO:0043616]; negative regulation of histone acetylation [GO:0035067]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of histone deacetylation [GO:0031065]; retinal metabolic process [GO:0042574]; retinol metabolic process [GO:0042572] GO:0000122; GO:0003714; GO:0004745; GO:0005634; GO:0005789; GO:0005811; GO:0016616; GO:0017053; GO:0031065; GO:0035067; GO:0042572; GO:0042574; GO:0043616; GO:0061629; GO:0140297 6438 XM_044326863.1 21 4 182 47 220 Q16445 6.07e-61 Gamma-aminobutyric acid receptor subunit alpha-6 (GABA(A) receptor subunit alpha-6) Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid signaling pathway [GO:0007214]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; regulation of postsynaptic membrane potential [GO:0060078]; signal transduction [GO:0007165]; synaptic transmission, GABAergic [GO:0051932] GO:0004890; GO:0005231; GO:0005237; GO:0005886; GO:0007165; GO:0007214; GO:0007268; GO:0008503; GO:0022851; GO:0030594; GO:0032590; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051932; GO:0060078; GO:0098794; GO:0099192; GO:1902476; GO:1902711; GO:1904315 6439 XM_044319169.1 0 0 77 8 26 O88917 9.83e-49 Adhesion G protein-coupled receptor L1 (Calcium-independent alpha-latrotoxin receptor 1) (CIRL-1) (Latrophilin-1) Rattus norvegicus (Rat) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; brain development [GO:0007420]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell surface receptor signaling pathway [GO:0007166]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synapse maturation [GO:0090129] GO:0004930; GO:0005886; GO:0007157; GO:0007166; GO:0007189; GO:0007420; GO:0014069; GO:0015643; GO:0016524; GO:0030246; GO:0030424; GO:0030426; GO:0035584; GO:0042734; GO:0043005; GO:0045202; GO:0050839; GO:0051965; GO:0090129; GO:0098978 6440 XM_044326241.1 53 17 10 118 19 NA NA NA NA NA NA 6441 XR_006392589.1 224 84 143 206 286 NA NA NA NA NA NA 6442 XM_044309180.1 60 0 21 0 73 B0UY98 3.8e-23 NA NA NA NA 6443 XM_044318251.1 111 49 55 15 126 P07314 6.97e-140 Glutathione hydrolase 1 proenzyme (EC 3.4.19.13) (Gamma-glutamyltransferase 1) (Gamma-glutamyltranspeptidase 1) (GGT 1) (EC 2.3.2.2) (Leukotriene-C4 hydrolase) (EC 3.4.19.14) (CD antigen CD224) [Cleaved into: Glutathione hydrolase 1 heavy chain; Glutathione hydrolase 1 light chain] Rattus norvegicus (Rat) aging [GO:0007568]; amino acid metabolic process [GO:0006520]; cellular response to oxidative stress [GO:0034599]; cysteine biosynthetic process [GO:0019344]; fatty acid metabolic process [GO:0006631]; glutamate metabolic process [GO:0006536]; glutathione biosynthetic process [GO:0006750]; glutathione catabolic process [GO:0006751]; hepatoblast differentiation [GO:0061017]; hepatocyte differentiation [GO:0070365]; leukotriene D4 biosynthetic process [GO:1901750]; leukotriene metabolic process [GO:0006691]; liver regeneration [GO:0097421]; peptide modification [GO:0031179]; proteolysis [GO:0006508]; regulation of immune system process [GO:0002682]; regulation of inflammatory response [GO:0050727]; response to alcohol [GO:0097305]; response to estradiol [GO:0032355]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]; spermatogenesis [GO:0007283]; zymogen activation [GO:0031638] GO:0000048; GO:0002682; GO:0002951; GO:0005615; GO:0005886; GO:0006508; GO:0006520; GO:0006536; GO:0006631; GO:0006691; GO:0006750; GO:0006751; GO:0007283; GO:0007568; GO:0016755; GO:0019344; GO:0031179; GO:0031638; GO:0031982; GO:0032355; GO:0032496; GO:0034599; GO:0034612; GO:0036374; GO:0050727; GO:0061017; GO:0070365; GO:0097305; GO:0097421; GO:0102953; GO:0103068; GO:1901750 6444 XM_029334079.2 361 0 0 267 0 P79955 1.14e-135 Carboxy-terminal kinesin 2 (XCTK2) Xenopus laevis (African clawed frog) microtubule-based movement [GO:0007018] GO:0003777; GO:0005524; GO:0005737; GO:0005874; GO:0007018; GO:0008017 6445 XR_006393379.1 13 35 63 14 267 NA NA NA NA NA NA 6446 XM_044328939.1 11 202 10 15 0 Q2LE78 8.16e-79 BTB/POZ domain-containing protein 6 Xenopus laevis (African clawed frog) NA GO:0005737 6447 XR_003826494.2 5 0 7 2 0 NA NA NA NA NA NA 6448 XM_029341067.2 24 25 21 29 41 NA NA NA NA NA NA 6449 XM_044324202.1 2218 1321 706 1369 1493 Q99614 4.44e-47 Tetratricopeptide repeat protein 1 (TPR repeat protein 1) Homo sapiens (Human) protein folding [GO:0006457] GO:0005778; GO:0005829; GO:0006457; GO:0051082 6450 XM_044312212.1 0 0 18 0 158 NA NA NA NA NA NA 6451 XM_029339291.2 1856 1950 1215 1544 1247 O60762 5.92e-146 Dolichol-phosphate mannosyltransferase subunit 1 (EC 2.4.1.83) (Dolichol-phosphate mannose synthase subunit 1) (DPM synthase subunit 1) (Dolichyl-phosphate beta-D-mannosyltransferase subunit 1) (Mannose-P-dolichol synthase subunit 1) (MPD synthase subunit 1) Homo sapiens (Human) dolichol metabolic process [GO:0019348]; dolichol-linked oligosaccharide biosynthetic process [GO:0006488]; GDP-mannose metabolic process [GO:0019673]; GPI anchor biosynthetic process [GO:0006506]; protein mannosylation [GO:0035268]; protein N-linked glycosylation via asparagine [GO:0018279]; protein O-linked mannosylation [GO:0035269] GO:0004169; GO:0004582; GO:0005537; GO:0005634; GO:0005783; GO:0005789; GO:0006488; GO:0006506; GO:0016020; GO:0018279; GO:0019348; GO:0019673; GO:0033185; GO:0035268; GO:0035269; GO:0043178; GO:0046872 6452 XR_006395196.1 134 64 77 88 201 NA NA NA NA NA NA 6453 XM_029326695.2 55 18 16 57 53 NA NA NA NA NA NA 6454 XM_029339299.2 15 67 14 14 42 NA NA NA NA NA NA 6455 XM_044317102.1 63 82 77 45 3 NA NA NA NA NA NA 6456 XM_044315020.1 0 19 0 0 12 NA NA NA NA NA NA 6457 XM_029345490.2 266 166 0 548 22 Q8N0W4 4.62e-78 Neuroligin-4, X-linked (Neuroligin X) (HNLX) Homo sapiens (Human) adult behavior [GO:0030534]; brainstem development [GO:0003360]; cell-cell junction organization [GO:0045216]; cerebellum development [GO:0021549]; chemical synaptic transmission [GO:0007268]; learning [GO:0007612]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of excitatory postsynaptic potential [GO:0090394]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; organ growth [GO:0035265]; postsynaptic membrane assembly [GO:0097104]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; social behavior [GO:0035176]; synapse organization [GO:0050808]; synaptic vesicle endocytosis [GO:0048488]; vocalization behavior [GO:0071625] GO:0003360; GO:0005886; GO:0007158; GO:0007268; GO:0007612; GO:0009986; GO:0016020; GO:0021549; GO:0030182; GO:0030425; GO:0030534; GO:0031404; GO:0035176; GO:0035265; GO:0038023; GO:0042043; GO:0042803; GO:0045202; GO:0045216; GO:0048488; GO:0050804; GO:0050808; GO:0050839; GO:0060076; GO:0071625; GO:0090394; GO:0097104; GO:0097105; GO:0097110; GO:0098793; GO:0098839; GO:0098983; GO:0098985; GO:0099054; GO:0099634 6458 XR_003825451.2 265 202 386 207 31 NA NA NA NA NA NA 6459 XM_029329414.2 78 19 13 16 19 NA NA NA NA NA NA 6460 XM_029325570.2 19 12 40 150 20 NA NA NA NA NA NA 6461 XR_006396424.1 78 0 8 0 0 NA NA NA NA NA NA 6462 XM_029335141.2 764 490 359 679 307 O75689 4.8e-99 Arf-GAP with dual PH domain-containing protein 1 (Centaurin-alpha-1) (Cnt-a1) (Putative MAPK-activating protein PM25) Homo sapiens (Human) cell surface receptor signaling pathway [GO:0007166]; positive regulation of GTPase activity [GO:0043547]; regulation of GTPase activity [GO:0043087] GO:0005096; GO:0005547; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0007166; GO:0043087; GO:0043231; GO:0043533; GO:0043547; GO:0046872; GO:1902936 6463 XM_044322179.1 3859 1802 1671 2053 2420 Q9JK66 1.75e-118 E3 ubiquitin-protein ligase parkin (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) Rattus norvegicus (Rat) adult locomotory behavior [GO:0008344]; aggresome assembly [GO:0070842]; autophagy of mitochondrion [GO:0000422]; brain development [GO:0007420]; cellular response to hydrogen sulfide [GO:1904881]; cellular response to L-glutamate [GO:1905232]; cellular response to L-glutamine [GO:1904845]; cellular response to manganese ion [GO:0071287]; cellular response to toxic substance [GO:0097237]; dopamine metabolic process [GO:0042417]; dopamine uptake involved in synaptic transmission [GO:0051583]; free ubiquitin chain polymerization [GO:0010994]; learning [GO:0007612]; locomotory behavior [GO:0007626]; mitochondrial fission [GO:0000266]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; mitochondrion localization [GO:0051646]; mitochondrion organization [GO:0007005]; mitochondrion to lysosome transport [GO:0099074]; mitophagy [GO:0000423]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation by host of viral genome replication [GO:0044828]; negative regulation of actin filament bundle assembly [GO:0032232]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell death [GO:0060548]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903382]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of exosomal secretion [GO:1903542]; negative regulation of gene expression [GO:0010629]; negative regulation of glucokinase activity [GO:0033132]; negative regulation of insulin secretion [GO:0046676]; negative regulation of intralumenal vesicle formation [GO:1905366]; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902254]; negative regulation of JNK cascade [GO:0046329]; negative regulation of mitochondrial fission [GO:0090258]; negative regulation of mitochondrial fusion [GO:0010637]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of oxidative stress-induced neuron death [GO:1903204]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of primary amine oxidase activity [GO:1902283]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; negative regulation of spontaneous neurotransmitter secretion [GO:1904049]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron cellular homeostasis [GO:0070050]; norepinephrine metabolic process [GO:0042415]; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:0061734]; positive regulation of apoptotic process [GO:0043065]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of autophagy of mitochondrion [GO:1903599]; positive regulation of dendrite extension [GO:1903861]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of mitochondrial fusion [GO:0010636]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of mitophagy [GO:1901526]; positive regulation of mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of neurotransmitter uptake [GO:0051582]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein binding [GO:0032092]; positive regulation of protein linear polyubiquitination [GO:1902530]; positive regulation of protein localization to membrane [GO:1905477]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein destabilization [GO:0031648]; protein K11-linked ubiquitination [GO:0070979]; protein K48-linked ubiquitination [GO:0070936]; protein K6-linked ubiquitination [GO:0085020]; protein K63-linked ubiquitination [GO:0070534]; protein localization to mitochondrion [GO:0070585]; protein metabolic process [GO:0019538]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of autophagy [GO:0010506]; regulation of cellular response to oxidative stress [GO:1900407]; regulation of dopamine metabolic process [GO:0042053]; regulation of gene expression [GO:0010468]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mitochondrion organization [GO:0010821]; regulation of neurotransmitter secretion [GO:0046928]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; regulation of protein stability [GO:0031647]; regulation of protein ubiquitination [GO:0031396]; regulation of reactive oxygen species metabolic process [GO:2000377]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation protein catabolic process at presynapse [GO:0140251]; response to corticosterone [GO:0051412]; response to curcumin [GO:1904643]; response to endoplasmic reticulum stress [GO:0034976]; response to muscle activity [GO:0014850]; response to oxidative stress [GO:0006979]; response to unfolded protein [GO:0006986]; response to xenobiotic stimulus [GO:0009410]; startle response [GO:0001964]; synaptic transmission, dopaminergic [GO:0001963]; synaptic transmission, glutamatergic [GO:0035249]; ubiquitin-dependent protein catabolic process [GO:0006511]; zinc ion homeostasis [GO:0055069] GO:0000122; GO:0000139; GO:0000151; GO:0000209; GO:0000266; GO:0000422; GO:0000423; GO:0001664; GO:0001933; GO:0001963; GO:0001964; GO:0003714; GO:0003779; GO:0004842; GO:0005634; GO:0005737; GO:0005739; GO:0005741; GO:0005783; GO:0005789; GO:0005794; GO:0005829; GO:0006511; GO:0006513; GO:0006979; GO:0006986; GO:0007005; GO:0007420; GO:0007612; GO:0007626; GO:0008013; GO:0008021; GO:0008344; GO:0009410; GO:0010468; GO:0010498; GO:0010506; GO:0010628; GO:0010629; GO:0010636; GO:0010637; GO:0010821; GO:0010918; GO:0010994; GO:0014069; GO:0014850; GO:0015631; GO:0016235; GO:0016567; GO:0019538; GO:0019899; GO:0019900; GO:0019901; GO:0030163; GO:0030165; GO:0030424; GO:0030544; GO:0030672; GO:0031072; GO:0031396; GO:0031410; GO:0031624; GO:0031625; GO:0031647; GO:0031648; GO:0032092; GO:0032232; GO:0032436; GO:0032991; GO:0033132; GO:0034976; GO:0035249; GO:0035774; GO:0042053; GO:0042415; GO:0042417; GO:0042802; GO:0042826; GO:0042981; GO:0043005; GO:0043025; GO:0043065; GO:0043123; GO:0043130; GO:0043161; GO:0043195; GO:0043274; GO:0043388; GO:0043524; GO:0043653; GO:0044828; GO:0044877; GO:0045121; GO:0045202; GO:0045944; GO:0046329; GO:0046676; GO:0046872; GO:0046928; GO:0048471; GO:0050804; GO:0050821; GO:0051087; GO:0051412; GO:0051582; GO:0051583; GO:0051646; GO:0051865; GO:0051881; GO:0051967; GO:0055069; GO:0060548; GO:0061630; GO:0061734; GO:0070050; GO:0070534; GO:0070585; GO:0070842; GO:0070936; GO:0070979; GO:0071287; GO:0085020; GO:0090090; GO:0090141; GO:0090201; GO:0090258; GO:0090394; GO:0097237; GO:0097602; GO:0097708; GO:0098691; GO:0098779; GO:0098793; GO:0098794; GO:0098978; GO:0099072; GO:0099074; GO:0140251; GO:1900242; GO:1900407; GO:1901215; GO:1901526; GO:1901800; GO:1902236; GO:1902254; GO:1902283; GO:1902530; GO:1903204; GO:1903265; GO:1903377; GO:1903382; GO:1903427; GO:1903542; GO:1903599; GO:1903861; GO:1904049; GO:1904643; GO:1904845; GO:1904881; GO:1905232; GO:1905366; GO:1905477; GO:1990381; GO:1990444; GO:1990452; GO:2000377; GO:2000378; GO:2001171 6464 XM_044323714.1 12 5 4 35 7 NA NA NA NA NA NA 6465 XM_029358012.2 1185 1050 815 1036 1465 NA NA NA NA NA NA 6466 XM_029357321.2 68 0 7 0 23 Q96CG8 4e-41 Collagen triple helix repeat-containing protein 1 Homo sapiens (Human) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005576; GO:0005581; GO:0005615; GO:0016477; GO:0016528; GO:0017147; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0062023; GO:0090090; GO:0090103; GO:0090177 6467 XM_044318901.1 902 518 398 752 710 Q9NQH7 7.9e-144 Xaa-Pro aminopeptidase 3 (X-Pro aminopeptidase 3) (EC 3.4.11.9) (Aminopeptidase P3) (APP3) Homo sapiens (Human) glomerular filtration [GO:0003094]; protein processing [GO:0016485]; proteolysis [GO:0006508] GO:0003094; GO:0004177; GO:0005737; GO:0005739; GO:0005829; GO:0006508; GO:0008233; GO:0016485; GO:0030145; GO:0042803; GO:0070006 6468 XM_029345362.2 324 215 170 792 310 Q980A9 2.18e-37 Methionine synthase (EC 2.1.1.-) (Homocysteine methyltransferase) Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) methionine biosynthetic process [GO:0009086]; methylation [GO:0032259] GO:0003871; GO:0008270; GO:0009086; GO:0032259 6469 XM_029335689.2 64 140 138 343 23 NA NA NA NA NA NA 6470 XM_029331499.2 0 0 209 69 0 NA NA NA NA NA NA 6471 XM_044324309.1 0 0 44 0 26 Q92542 2.58e-130 Nicastrin Homo sapiens (Human) adult behavior [GO:0030534]; amyloid precursor protein biosynthetic process [GO:0042983]; amyloid precursor protein catabolic process [GO:0042987]; amyloid precursor protein metabolic process [GO:0042982]; amyloid-beta formation [GO:0034205]; cellular response to calcium ion [GO:0071277]; central nervous system myelination [GO:0022010]; cerebellum development [GO:0021549]; dopamine receptor signaling pathway [GO:0007212]; epithelial cell proliferation [GO:0050673]; glutamate receptor signaling pathway [GO:0007215]; learning or memory [GO:0007611]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; myeloid cell homeostasis [GO:0002262]; neuron apoptotic process [GO:0051402]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; positive regulation of amyloid precursor protein biosynthetic process [GO:0042986]; positive regulation of catalytic activity [GO:0043085]; positive regulation of endopeptidase activity [GO:0010950]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of long-term synaptic potentiation [GO:1900271]; short-term synaptic potentiation [GO:1990926]; T cell proliferation [GO:0042098] GO:0002262; GO:0005739; GO:0005765; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005925; GO:0006508; GO:0006509; GO:0007212; GO:0007215; GO:0007219; GO:0007220; GO:0007611; GO:0008021; GO:0010008; GO:0010950; GO:0016020; GO:0016485; GO:0021549; GO:0022010; GO:0030534; GO:0030674; GO:0031293; GO:0034205; GO:0035577; GO:0042098; GO:0042383; GO:0042470; GO:0042500; GO:0042734; GO:0042982; GO:0042983; GO:0042986; GO:0042987; GO:0043085; GO:0050673; GO:0051117; GO:0051402; GO:0070062; GO:0070765; GO:0070851; GO:0071277; GO:1900271; GO:1990926 6472 XM_029344668.2 512 127 0 397 348 P48416 9.3e-88 Cytochrome P450 10 (EC 1.14.-.-) (CYPX) Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004497; GO:0005506; GO:0016705; GO:0020037 6473 XM_044322436.1 48 65 32 146 49 A8MU46 7.15e-26 Smoothelin-like protein 1 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; muscle organ morphogenesis [GO:0048644]; negative regulation of DNA-templated transcription [GO:0045892]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of vasoconstriction [GO:0045907]; response to activity [GO:0014823]; response to xenobiotic stimulus [GO:0009410]; vasoconstriction [GO:0042310] GO:0005516; GO:0005523; GO:0005634; GO:0005737; GO:0005815; GO:0008157; GO:0009410; GO:0014823; GO:0018105; GO:0030036; GO:0031430; GO:0031674; GO:0031941; GO:0042310; GO:0043292; GO:0043621; GO:0045892; GO:0045907; GO:0048644; GO:0051401; GO:0097718 6474 XM_044312280.1 3880 2297 2155 3754 3145 Q14185 0 Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180) Homo sapiens (Human) apoptotic process [GO:0006915]; cell migration [GO:0016477]; integrin-mediated signaling pathway [GO:0007229]; myoblast fusion [GO:0007520]; phagocytosis, engulfment [GO:0006911]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264] GO:0005085; GO:0005096; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0006911; GO:0006915; GO:0007165; GO:0007229; GO:0007264; GO:0007520; GO:0010634; GO:0016477; GO:0016607; GO:0017124; GO:0031267; GO:0032045; GO:1900026 6475 XM_029356931.2 11 0 0 7 4 P62257 3.07e-94 Ubiquitin-conjugating enzyme E2 H (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme H) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme H) (UBCH2) (Ubiquitin carrier protein H) (Ubiquitin-conjugating enzyme E2-20K) (Ubiquitin-protein ligase H) Mus musculus (Mouse) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K11-linked ubiquitination [GO:0070979]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000209; GO:0004842; GO:0005524; GO:0005634; GO:0006511; GO:0043161; GO:0061631; GO:0070936; GO:0070979 6476 XM_029328599.2 1849 1632 1604 1816 2165 Q6NYI0 1.96e-25 Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein Danio rerio (Zebrafish) (Brachydanio rerio) endoplasmic reticulum unfolded protein response [GO:0030968] GO:0016020; GO:0030968 6477 XM_029325809.2 5 0 0 7 372 B8VIU6 8.85e-71 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 6478 XM_029333561.2 9520 9608 6563 10448 9606 P25228 2.34e-128 Ras-related protein Rab-3 Drosophila melanogaster (Fruit fly) cytoskeletal matrix organization at active zone [GO:0048789]; maintenance of presynaptic active zone structure [GO:0048790]; neurotransmitter secretion [GO:0007269]; protein localization to plasma membrane [GO:0072659]; protein secretion [GO:0009306]; Rab protein signal transduction [GO:0032482]; regulation of exocytosis [GO:0017157]; regulation of neurotransmitter secretion [GO:0046928]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic vesicle fusion to presynaptic active zone membrane [GO:0031630]; vesicle docking involved in exocytosis [GO:0006904]; vesicle-mediated transport [GO:0016192]; viral entry into host cell [GO:0046718] GO:0003924; GO:0005525; GO:0005768; GO:0005886; GO:0006904; GO:0007269; GO:0008021; GO:0009306; GO:0016192; GO:0017157; GO:0031489; GO:0031630; GO:0031982; GO:0032482; GO:0043231; GO:0045202; GO:0046718; GO:0046928; GO:0048172; GO:0048786; GO:0048789; GO:0048790; GO:0072659 6479 XM_029339282.2 70 47 35 141 50 NA NA NA NA NA NA 6480 XM_044326208.1 72 37 20 18 74 NA NA NA NA NA NA 6481 XM_029333988.2 112 0 217 54 11 NA NA NA NA NA NA 6482 XM_029343975.2 179 0 93 234 386 B9EJ86 0 Oxysterol-binding protein-related protein 8 (ORP-8) (OSBP-related protein 8) Mus musculus (Mouse) activation of protein kinase B activity [GO:0032148]; fat cell differentiation [GO:0045444]; negative regulation of cell migration [GO:0030336]; negative regulation of sequestering of triglyceride [GO:0010891]; phospholipid transport [GO:0015914]; positive regulation of glucose import [GO:0046326]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of protein kinase B signaling [GO:0051897]; protein localization to nuclear pore [GO:0090204] GO:0001786; GO:0005783; GO:0005789; GO:0005829; GO:0010891; GO:0015248; GO:0015485; GO:0015914; GO:0016020; GO:0030336; GO:0031965; GO:0032148; GO:0032541; GO:0032934; GO:0043231; GO:0045444; GO:0046326; GO:0046628; GO:0051897; GO:0070273; GO:0090204; GO:0140343 6483 XM_044326682.1 627 2898 1141 654 835 NA NA NA NA NA NA 6484 XM_029354163.2 154 16 35 16 244 NA NA NA NA NA NA 6485 XM_029332067.2 189 86 60 161 331 Q9C0D2 1.47e-34 Centrosomal protein of 295 kDa Homo sapiens (Human) centriole replication [GO:0007099]; positive regulation of centriole elongation [GO:1903724]; positive regulation of centrosome duplication [GO:0010825]; positive regulation of establishment of protein localization [GO:1904951]; positive regulation of protein acetylation [GO:1901985]; regulation of centriole replication [GO:0046599] GO:0005737; GO:0005813; GO:0005814; GO:0005829; GO:0005856; GO:0005886; GO:0007099; GO:0008017; GO:0010825; GO:0046599; GO:1901985; GO:1903724; GO:1904951; GO:1990498 6486 XR_006391948.1 4 12 11 12 11 NA NA NA NA NA NA 6487 XM_029358139.2 156 124 70 129 285 P29146 0 PC3-like endoprotease variant A (EC 3.4.21.-) (SPC3) Hydra vulgaris (Hydra) (Hydra attenuata) proteolysis [GO:0006508] GO:0004252; GO:0006508 6488 XM_029350951.2 287 95 117 292 277 Q6P1S4 0 Arginine--tRNA ligase, cytoplasmic (EC 6.1.1.19) (Arginyl-tRNA synthetase) (ArgRS) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) arginyl-tRNA aminoacylation [GO:0006420] GO:0004814; GO:0005524; GO:0005829; GO:0006420; GO:0017101 6489 XM_029352076.2 0 0 0 0 188 Q9Y6R4 3.71e-36 Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAP three kinase 1) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4) Homo sapiens (Human) chorionic trophoblast cell differentiation [GO:0060718]; intracellular signal transduction [GO:0035556]; male germ-line sex determination [GO:0019100]; MAPK cascade [GO:0000165]; placenta development [GO:0001890]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein phosphorylation [GO:0006468]; regulation of gene expression [GO:0010468]; response to UV-C [GO:0010225] GO:0000165; GO:0001890; GO:0004709; GO:0005524; GO:0005737; GO:0006468; GO:0010225; GO:0010468; GO:0019100; GO:0032212; GO:0035556; GO:0043507; GO:0046872; GO:0048471; GO:0051973; GO:0060718; GO:0106310; GO:1900745; GO:1904355 6490 XM_044308072.1 692 5 0 421 439 Q8IV61 3.77e-134 Ras guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1) Homo sapiens (Human) MAPK cascade [GO:0000165]; positive regulation of GTPase activity [GO:0043547]; Ras protein signal transduction [GO:0007265]; small GTPase mediated signal transduction [GO:0007264] GO:0000165; GO:0005085; GO:0005096; GO:0005509; GO:0005886; GO:0007264; GO:0007265; GO:0019900; GO:0019992; GO:0031267; GO:0032045; GO:0043547; GO:0048471 6491 XM_029354680.2 470 332 212 282 364 O15992 0 Arginine kinase (AK) (EC 2.7.3.3) Anthopleura japonica (Sea anemone) phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310] GO:0004054; GO:0004111; GO:0005524; GO:0016310; GO:0046314 6492 XM_044310213.1 7 0 0 0 19 NA NA NA NA NA NA 6493 XM_029331212.2 743 799 509 578 342 Q6PBK1 1.67e-40 Protein MIX23 (Coiled-coil domain-containing protein 58) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005739; GO:0005758 6494 XM_029329176.2 758 268 347 366 538 Q92643 2.84e-156 GPI-anchor transamidase (GPI transamidase) (EC 3.-.-.-) (GPI8 homolog) (hGPI8) (Phosphatidylinositol-glycan biosynthesis class K protein) (PIG-K) Homo sapiens (Human) attachment of GPI anchor to protein [GO:0016255]; proteolysis [GO:0006508] GO:0003756; GO:0003923; GO:0005789; GO:0006508; GO:0016020; GO:0016255; GO:0042765 6495 XM_029357783.2 13 19 22 20 68 P16066 0 Atrial natriuretic peptide receptor 1 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type A) (ANP-A) (ANPR-A) (NPR-A) (Guanylate cyclase A) (GC-A) Homo sapiens (Human) blood vessel diameter maintenance [GO:0097746]; body fluid secretion [GO:0007589]; cell surface receptor signaling pathway [GO:0007166]; cGMP biosynthetic process [GO:0006182]; cGMP-mediated signaling [GO:0019934]; dopamine metabolic process [GO:0042417]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell growth [GO:0030308]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of cGMP-mediated signaling [GO:0010753]; positive regulation of renal sodium excretion [GO:0035815]; positive regulation of urine volume [GO:0035810]; protein phosphorylation [GO:0006468]; receptor guanylyl cyclase signaling pathway [GO:0007168]; regulation of blood pressure [GO:0008217]; regulation of vascular permeability [GO:0043114]; signal transduction [GO:0007165] GO:0001653; GO:0004383; GO:0004672; GO:0005524; GO:0005525; GO:0005886; GO:0006182; GO:0006468; GO:0007165; GO:0007166; GO:0007168; GO:0007589; GO:0008217; GO:0008528; GO:0010753; GO:0016525; GO:0016941; GO:0017046; GO:0019934; GO:0030308; GO:0035810; GO:0035815; GO:0042417; GO:0042562; GO:0043114; GO:0043235; GO:0048662; GO:0097746; GO:1990620 6496 XM_029332308.2 1211 664 509 1071 689 NA NA NA NA NA NA 6497 XR_006397489.1 0 13 7 0 4 NA NA NA NA NA NA 6498 XM_044313707.1 145 39 71 63 176 NA NA NA NA NA NA 6499 XM_044317442.1 51 14 15 18 5 Q9UL62 1.07e-59 Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (TRP-5) (hTRP-5) (hTRP5) Homo sapiens (Human) calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; negative regulation of dendrite morphogenesis [GO:0050774]; nervous system development [GO:0007399]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; phosphatidylserine exposure on apoptotic cell surface [GO:0070782]; positive regulation of axon extension [GO:0045773]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of membrane hyperpolarization [GO:1902630] GO:0003779; GO:0005262; GO:0005737; GO:0005886; GO:0006816; GO:0007204; GO:0007399; GO:0008284; GO:0010800; GO:0015279; GO:0030182; GO:0030276; GO:0030425; GO:0030426; GO:0034703; GO:0034704; GO:0042805; GO:0043025; GO:0045121; GO:0045666; GO:0045773; GO:0050774; GO:0051117; GO:0051402; GO:0051480; GO:0070588; GO:0070679; GO:0070782; GO:1902630 6500 XM_044312055.1 3265 2366 1211 1728 847 Q06BR2 7.91e-46 Amyloid-beta precursor-like protein Doryteuthis pealeii (Longfin inshore squid) (Loligo pealeii) NA GO:0005886; GO:0008201; GO:0030424; GO:0046914 6501 XM_029341185.2 2105 1645 1015 2244 1962 Q62717 0 Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1) (rCAPS) Rattus norvegicus (Rat) catecholamine secretion [GO:0050432]; establishment of localization in cell [GO:0051649]; exocytosis [GO:0006887]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of exocytosis [GO:0045921]; presynaptic dense core vesicle exocytosis [GO:0099525]; protein transport [GO:0015031]; regulated exocytosis [GO:0045055]; synaptic vesicle priming [GO:0016082]; vesicle organization [GO:0016050] GO:0005509; GO:0005546; GO:0006887; GO:0015031; GO:0016050; GO:0016082; GO:0019901; GO:0031045; GO:0031410; GO:0045055; GO:0045921; GO:0045956; GO:0050432; GO:0051649; GO:0098674; GO:0098793; GO:0098978; GO:0099525 6502 XR_006395873.1 382 237 298 414 294 NA NA NA NA NA NA 6503 XR_006397293.1 54 12 81 27 97 NA NA NA NA NA NA 6504 XM_044318477.1 1567 869 817 2184 2054 Q6PDN3 3.74e-88 Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Kinase-related protein) (KRP) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form] Mus musculus (Mouse) aorta smooth muscle tissue morphogenesis [GO:0060414]; bleb assembly [GO:0032060]; cellular hypotonic response [GO:0071476]; cellular response to calcium ion [GO:0071277]; cellular response to potassium ion [GO:0035865]; cellular response to xenobiotic stimulus [GO:0071466]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cell migration [GO:0030335]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; smooth muscle contraction [GO:0006939]; tonic smooth muscle contraction [GO:0014820] GO:0001725; GO:0003779; GO:0004672; GO:0004687; GO:0005516; GO:0005524; GO:0005737; GO:0005886; GO:0005911; GO:0006468; GO:0006939; GO:0014820; GO:0015629; GO:0019899; GO:0030027; GO:0030335; GO:0032060; GO:0032154; GO:0035865; GO:0046872; GO:0051928; GO:0060414; GO:0071277; GO:0071466; GO:0071476; GO:0090303 6505 XM_044318477.1 1567 869 817 2184 2054 Q6PDN3 1.23e-60 Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Kinase-related protein) (KRP) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form] Mus musculus (Mouse) aorta smooth muscle tissue morphogenesis [GO:0060414]; bleb assembly [GO:0032060]; cellular hypotonic response [GO:0071476]; cellular response to calcium ion [GO:0071277]; cellular response to potassium ion [GO:0035865]; cellular response to xenobiotic stimulus [GO:0071466]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cell migration [GO:0030335]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; smooth muscle contraction [GO:0006939]; tonic smooth muscle contraction [GO:0014820] GO:0001725; GO:0003779; GO:0004672; GO:0004687; GO:0005516; GO:0005524; GO:0005737; GO:0005886; GO:0005911; GO:0006468; GO:0006939; GO:0014820; GO:0015629; GO:0019899; GO:0030027; GO:0030335; GO:0032060; GO:0032154; GO:0035865; GO:0046872; GO:0051928; GO:0060414; GO:0071277; GO:0071466; GO:0071476; GO:0090303 6506 XM_044314911.1 10 0 0 38 0 NA NA NA NA NA NA 6507 XM_029355513.2 76 11 66 37 87 Q90481 2.21e-34 Homeobox protein Nkx-2.2a (Homeobox protein NK-2 homolog B-A) Danio rerio (Zebrafish) (Brachydanio rerio) cell differentiation [GO:0030154]; endocrine pancreas development [GO:0031018]; floor plate development [GO:0033504]; floor plate formation [GO:0021508]; glial cell migration [GO:0008347]; motor neuron axon guidance [GO:0008045]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357]; Schwann cell development [GO:0014044]; spinal cord oligodendrocyte cell differentiation [GO:0021529]; spinal cord oligodendrocyte cell fate specification [GO:0021530]; ventral spinal cord interneuron differentiation [GO:0021514] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0008045; GO:0008347; GO:0014044; GO:0021508; GO:0021514; GO:0021529; GO:0021530; GO:0030154; GO:0031018; GO:0033504; GO:0045893 6508 XM_029337452.2 5 63 0 0 12 Q9DCV4 9.61e-71 Regulator of microtubule dynamics protein 1 (RMD-1) (mRMD-1) (Microtubule-associated protein) (Protein FAM82B) Mus musculus (Mouse) NA GO:0005737; GO:0005739; GO:0005876; GO:0008017; GO:0097431 6509 XM_029352783.2 148 68 79 126 108 NA NA NA NA NA NA 6510 XM_044323213.1 17 43 2 30 23 NA NA NA NA NA NA 6511 XM_029357816.2 151 29 107 54 132 Q4LDE5 5.02e-37 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 6512 XM_029352093.2 46 56 27 55 126 Q5U4U4 6.37e-79 Protein downstream neighbor of son homolog Xenopus laevis (African clawed frog) cell division [GO:0051301]; DNA damage checkpoint signaling [GO:0000077]; DNA replication [GO:0006260]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; replication fork protection [GO:0048478] GO:0000077; GO:0005634; GO:0005657; GO:0006260; GO:0007095; GO:0030894; GO:0048478; GO:0051301 6513 XM_044311189.1 494 351 548 621 556 NA NA NA NA NA NA 6514 XM_029335906.2 1397 1129 176 1111 940 Q9NWX6 2.17e-114 Probable tRNA(His) guanylyltransferase (EC 2.7.7.79) (Induced in high glucose-1) (IHG-1) (Interphase cytoplasmic foci protein 45) (tRNA-histidine guanylyltransferase) Homo sapiens (Human) mitochondrial fusion [GO:0008053]; protein homotetramerization [GO:0051289]; response to oxidative stress [GO:0006979]; stress-induced mitochondrial fusion [GO:1990046]; tRNA modification [GO:0006400]; tRNA processing [GO:0008033] GO:0000049; GO:0000287; GO:0005085; GO:0005524; GO:0005525; GO:0005739; GO:0005741; GO:0005829; GO:0006400; GO:0006979; GO:0008033; GO:0008053; GO:0008193; GO:0016779; GO:0042802; GO:0051289; GO:1990046; GO:1990234 6515 XM_044327716.1 11 4 17 13 70 NA NA NA NA NA NA 6516 XM_029344430.2 0 14 0 167 15 Q5F356 6.34e-120 Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha (EC 2.7.1.149) (1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha) (Diphosphoinositide kinase 2-alpha) (Phosphatidylinositol 5-phosphate 4-kinase type II alpha) (PI(5)P 4-kinase type II alpha) (PIP4KII-alpha) (PtdIns(5)P-4-kinase isoform 2-alpha) Gallus gallus (Chicken) 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process [GO:1902635]; autophagosome-lysosome fusion [GO:0061909]; phosphatidylinositol phosphate biosynthetic process [GO:0046854]; phosphorylation [GO:0016310]; regulation of autophagy [GO:0010506]; vesicle-mediated cholesterol transport [GO:0090119] GO:0005524; GO:0005634; GO:0005764; GO:0005829; GO:0005886; GO:0010506; GO:0016308; GO:0016309; GO:0016310; GO:0042803; GO:0046854; GO:0061909; GO:0090119; GO:1902635 6517 XR_006391773.1 92 177 346 188 78 NA NA NA NA NA NA 6518 XM_044312151.1 2 0 6 0 30 NA NA NA NA NA NA 6519 XM_029348515.2 308 281 408 380 412 NA NA NA NA NA NA 6520 XM_044314945.1 22 7 19 0 58 NA NA NA NA NA NA 6521 XR_003825230.2 108 115 57 91 144 NA NA NA NA NA NA 6522 XM_029342406.2 31 9 19 48 33 NA NA NA NA NA NA 6523 XM_029334457.2 0 0 0 351 1249 Q26636 1.86e-124 Cathepsin L (EC 3.4.22.15) [Cleaved into: Cathepsin L heavy chain; Cathepsin L light chain] Sarcophaga peregrina (Flesh fly) (Boettcherisca peregrina) cell differentiation [GO:0030154]; proteolysis [GO:0006508] GO:0004197; GO:0005764; GO:0006508; GO:0030154 6524 XM_029349723.2 155 79 59 0 113 Q9J569 3.1e-25 Putative ankyrin repeat protein FPV162 Fowlpox virus (strain NVSL) (FPV) NA NA 6525 XM_044326854.1 68 86 96 52 71 NA NA NA NA NA NA 6526 XR_006392576.1 23 41 20 24 72 NA NA NA NA NA NA 6527 XM_029339757.2 1714 949 1023 1812 1672 Q8BTI8 4.07e-38 Serine/arginine repetitive matrix protein 2 Mus musculus (Mouse) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0003729; GO:0005634; GO:0015030; GO:0016607; GO:0047485; GO:0070742; GO:0071005; GO:0071007; GO:0071013 6528 XM_044321949.1 149 0 111 2 19 NA NA NA NA NA NA 6529 XM_044309230.1 136 78 111 201 236 NA NA NA NA NA NA 6530 XM_044324173.1 787 637 728 872 1382 NA NA NA NA NA NA 6531 XM_044307545.1 35 92 112 38 57 Q6TV19 7.76e-138 Endoribonuclease Dicer (EC 3.1.26.3) Danio rerio (Zebrafish) (Brachydanio rerio) apoptotic DNA fragmentation [GO:0006309]; cranial skeletal system development [GO:1904888]; global gene silencing by mRNA cleavage [GO:0098795]; heterochromatin formation [GO:0031507]; melanocyte differentiation [GO:0030318]; miRNA processing [GO:0035196]; miRNA-mediated gene silencing [GO:0035195]; miRNA-mediated gene silencing by mRNA destabilization [GO:0035279]; neural crest cell development [GO:0014032]; pre-miRNA processing [GO:0031054]; regulation of neurogenesis [GO:0050767]; RNA phosphodiester bond hydrolysis [GO:0090501]; siRNA processing [GO:0030422]; ventricular system development [GO:0021591] GO:0003723; GO:0004386; GO:0004525; GO:0004530; GO:0005524; GO:0005634; GO:0005737; GO:0006309; GO:0014032; GO:0016442; GO:0021591; GO:0030318; GO:0030422; GO:0031054; GO:0031507; GO:0035195; GO:0035196; GO:0035279; GO:0046872; GO:0050767; GO:0070578; GO:0070883; GO:0090501; GO:0098795; GO:1904888 6532 XM_044307545.1 35 92 112 38 57 Q6TV19 1.38e-66 Endoribonuclease Dicer (EC 3.1.26.3) Danio rerio (Zebrafish) (Brachydanio rerio) apoptotic DNA fragmentation [GO:0006309]; cranial skeletal system development [GO:1904888]; global gene silencing by mRNA cleavage [GO:0098795]; heterochromatin formation [GO:0031507]; melanocyte differentiation [GO:0030318]; miRNA processing [GO:0035196]; miRNA-mediated gene silencing [GO:0035195]; miRNA-mediated gene silencing by mRNA destabilization [GO:0035279]; neural crest cell development [GO:0014032]; pre-miRNA processing [GO:0031054]; regulation of neurogenesis [GO:0050767]; RNA phosphodiester bond hydrolysis [GO:0090501]; siRNA processing [GO:0030422]; ventricular system development [GO:0021591] GO:0003723; GO:0004386; GO:0004525; GO:0004530; GO:0005524; GO:0005634; GO:0005737; GO:0006309; GO:0014032; GO:0016442; GO:0021591; GO:0030318; GO:0030422; GO:0031054; GO:0031507; GO:0035195; GO:0035196; GO:0035279; GO:0046872; GO:0050767; GO:0070578; GO:0070883; GO:0090501; GO:0098795; GO:1904888 6533 XM_044322083.1 0 0 2 18 0 B1AJZ9 1.4e-28 Forkhead-associated domain-containing protein 1 (FHA domain-containing protein 1) Homo sapiens (Human) NA NA 6534 XM_044322083.1 0 0 2 18 0 B1AJZ9 4.9e-26 Forkhead-associated domain-containing protein 1 (FHA domain-containing protein 1) Homo sapiens (Human) NA NA 6535 XM_044307549.1 0 0 17 99 13 Q502W6 0 von Willebrand factor A domain-containing protein 3B (VWA domain-containing protein 3B) Homo sapiens (Human) NA GO:0005654; GO:0005829 6536 XM_029330439.2 599 667 371 482 516 NA NA NA NA NA NA 6537 XR_006392375.1 3 1 9 4 0 NA NA NA NA NA NA 6538 XM_044323414.1 27 2 0 8 3 NA NA NA NA NA NA 6539 XM_029340840.2 688 721 464 810 585 Q0IHQ9 4.4e-40 2-phosphoxylose phosphatase 1 (EC 3.1.3.-) (Acid phosphatase-like protein 2) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) chondroitin sulfate proteoglycan biosynthetic process [GO:0050650]; glycosaminoglycan biosynthetic process [GO:0006024]; positive regulation of heparan sulfate proteoglycan biosynthetic process [GO:0010909] GO:0000139; GO:0005794; GO:0006024; GO:0010909; GO:0016791; GO:0050650 6540 XM_044322679.1 9 119 13 80 6 NA NA NA NA NA NA 6541 XR_003826872.2 23 0 0 25 18 NA NA NA NA NA NA 6542 XM_044315930.1 3 0 0 11 42 NA NA NA NA NA NA 6543 XM_044308056.1 9 119 73 0 0 NA NA NA NA NA NA 6544 XM_044326005.1 16 44 40 66 96 NA NA NA NA NA NA 6545 XM_029357931.2 17 13 17 10 11 NA NA NA NA NA NA 6546 XM_044323127.1 2878 2147 1539 2231 1947 F8WLE0 4.35e-164 Kinesin-like protein KIF28P (Kinesin-like protein 6) Rattus norvegicus (Rat) microtubule-based movement [GO:0007018]; mitochondrion organization [GO:0007005]; organelle transport along microtubule [GO:0072384] GO:0003777; GO:0005524; GO:0005871; GO:0005874; GO:0007005; GO:0007018; GO:0008017; GO:0016887; GO:0031966; GO:0072384 6547 XR_006394840.1 602 219 679 872 2886 NA NA NA NA NA NA 6548 XM_029333746.2 3 21 0 3 0 Q61176 1.35e-84 Arginase-1 (EC 3.5.3.1) (Liver-type arginase) (Type I arginase) Mus musculus (Mouse) adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; negative regulation of type II interferon-mediated signaling pathway [GO:0060336]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; regulation of L-arginine import across plasma membrane [GO:1905541]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to xenobiotic stimulus [GO:0009410]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050] GO:0000050; GO:0001889; GO:0001938; GO:0002250; GO:0004053; GO:0005615; GO:0005737; GO:0005741; GO:0005829; GO:0006525; GO:0007568; GO:0009410; GO:0009635; GO:0010042; GO:0010043; GO:0010269; GO:0014075; GO:0019547; GO:0030145; GO:0030324; GO:0032964; GO:0033189; GO:0033197; GO:0042130; GO:0042802; GO:0042832; GO:0043005; GO:0043025; GO:0043200; GO:0045087; GO:0046007; GO:0046686; GO:0048678; GO:0051597; GO:0060056; GO:0060135; GO:0060336; GO:0070301; GO:0070965; GO:0071222; GO:0071353; GO:0071377; GO:0071549; GO:0071560; GO:1905541; GO:2000552 6549 XM_044316954.1 1333 495 450 1139 1809 Q98931 2.58e-125 Low-density lipoprotein receptor-related protein 8 (LRP-8) (Apolipoprotein E receptor 2) (Protein LR8B) Gallus gallus (Chicken) endocytosis [GO:0006897]; ventral spinal cord development [GO:0021517] GO:0005509; GO:0006897; GO:0016020; GO:0021517 6550 XM_029325595.2 7025 10160 4067 6462 2817 NA NA NA NA NA NA 6551 XM_029343195.2 1908 1278 769 3820 2095 NA NA NA NA NA NA 6552 XM_044325537.1 2469 2206 1565 3047 2075 Q2VJ60 3.17e-155 E3 ubiquitin-protein ligase RNF19A (EC 2.3.2.31) (Double ring-finger protein) (Dorfin) (RING finger protein 19A) Sus scrofa (Pig) positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000151; GO:0000209; GO:0005737; GO:0005815; GO:0006511; GO:0016020; GO:0031624; GO:0032436; GO:0046872; GO:0061630; GO:0098686; GO:0098794; GO:0098978; GO:0099576 6553 XM_044312771.1 4 0 10 18 6 P69478 1e-33 Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4S-1) (C4ST-1) (C4ST1) Rattus norvegicus (Rat) apoptotic process [GO:0006915]; carbohydrate biosynthetic process [GO:0016051]; cartilage development [GO:0051216]; chondrocyte development [GO:0002063]; chondroitin sulfate biosynthetic process [GO:0030206]; chondroitin sulfate metabolic process [GO:0030204]; developmental growth [GO:0048589]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; embryonic viscerocranium morphogenesis [GO:0048703]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; polysaccharide localization [GO:0033037]; post-anal tail morphogenesis [GO:0036342]; post-embryonic development [GO:0009791]; proteoglycan biosynthetic process [GO:0030166]; regulation of cell population proliferation [GO:0042127]; respiratory gaseous exchange by respiratory system [GO:0007585]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0000139; GO:0001537; GO:0001701; GO:0002063; GO:0006915; GO:0007179; GO:0007585; GO:0008146; GO:0009791; GO:0016051; GO:0030166; GO:0030204; GO:0030206; GO:0030326; GO:0030512; GO:0033037; GO:0036342; GO:0042127; GO:0042733; GO:0043066; GO:0047756; GO:0048589; GO:0048703; GO:0048704; GO:0050659; GO:0051216 6554 XM_029336541.2 146 99 107 122 94 NA NA NA NA NA NA 6555 XM_044324361.1 101 125 117 147 154 NA NA NA NA NA NA 6556 XM_029334777.2 162 72 98 95 129 Q5RF73 4.05e-79 Transmembrane protein 19 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0016020 6557 XR_006398116.1 0 0 8 0 4 NA NA NA NA NA NA 6558 XM_029330687.2 2677 3468 1513 2834 2582 Q9P2T1 0 GMP reductase 2 (GMPR 2) (EC 1.7.1.7) (Guanosine 5'-monophosphate oxidoreductase 2) (Guanosine monophosphate reductase 2) Homo sapiens (Human) GMP metabolic process [GO:0046037]; purine nucleobase metabolic process [GO:0006144] GO:0003920; GO:0005829; GO:0006144; GO:0046037; GO:0046872; GO:1902560 6559 XM_044315958.1 4 35 38 20 102 NA NA NA NA NA NA 6560 XM_029355852.2 82 47 42 74 103 Q5U2V5 4.62e-51 Cardiolipin synthase (CMP-forming) (CLS) (EC 2.7.8.41) Rattus norvegicus (Rat) cardiolipin biosynthetic process [GO:0032049]; glycerophospholipid biosynthetic process [GO:0046474]; response to phosphatidylethanolamine [GO:1905711]; response to thyroxine [GO:0097068] GO:0005739; GO:0005743; GO:0008808; GO:0031966; GO:0032049; GO:0043337; GO:0046474; GO:0097068; GO:1905711 6561 XM_029327177.2 71 28 54 57 293 NA NA NA NA NA NA 6562 XM_029333596.2 816 790 716 748 574 Q9NZ01 2.38e-111 Very-long-chain enoyl-CoA reductase (EC 1.3.1.93) (Synaptic glycoprotein SC2) (Trans-2,3-enoyl-CoA reductase) (TER) Homo sapiens (Human) fatty acid elongation [GO:0030497]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; sphingolipid metabolic process [GO:0006665]; very long-chain fatty acid biosynthetic process [GO:0042761] GO:0005634; GO:0005783; GO:0005789; GO:0006665; GO:0016491; GO:0017099; GO:0030497; GO:0035338; GO:0042761; GO:0102758 6563 XM_044317948.1 1086 9 1216 12 508 NA NA NA NA NA NA 6564 XR_006397040.1 0 82 133 13 0 NA NA NA NA NA NA 6565 XM_029323501.2 151 147 84 181 296 NA NA NA NA NA NA 6566 XM_029329008.2 20 51 30 44 30 NA NA NA NA NA NA 6567 XM_029347699.2 852 645 722 722 829 Q14CX7 0 N-alpha-acetyltransferase 25, NatB auxiliary subunit (Mitochondrial distribution and morphology protein 20) (N-terminal acetyltransferase B complex subunit MDM20) (NatB complex subunit MDM20) (N-terminal acetyltransferase B complex subunit NAA25) (p120) Homo sapiens (Human) N-terminal peptidyl-methionine acetylation [GO:0017196] GO:0005737; GO:0005794; GO:0005829; GO:0017196; GO:0031416 6568 XR_003823760.2 18 33 6 25 50 NA NA NA NA NA NA 6569 XM_044324494.1 59 59 20 2 120 NA NA NA NA NA NA 6570 XM_044315734.1 0 11 12 0 0 Q5XI13 3.61e-30 Glutamate-rich WD repeat-containing protein 1 Rattus norvegicus (Rat) DNA replication [GO:0006260]; nucleosome assembly [GO:0006334]; nucleosome disassembly [GO:0006337]; ribosome biogenesis [GO:0042254] GO:0003682; GO:0003688; GO:0005634; GO:0005694; GO:0005730; GO:0006260; GO:0006334; GO:0006337; GO:0032991; GO:0042254; GO:0042393 6571 XM_044315734.1 0 11 12 0 0 Q5XI13 3.61e-30 Glutamate-rich WD repeat-containing protein 1 Rattus norvegicus (Rat) DNA replication [GO:0006260]; nucleosome assembly [GO:0006334]; nucleosome disassembly [GO:0006337]; ribosome biogenesis [GO:0042254] GO:0003682; GO:0003688; GO:0005634; GO:0005694; GO:0005730; GO:0006260; GO:0006334; GO:0006337; GO:0032991; GO:0042254; GO:0042393 6572 XR_003824024.2 4983 3199 6805 5878 5523 NA NA NA NA NA NA 6573 XM_029340998.2 0 0 8 1 0 NA NA NA NA NA NA 6574 XM_029337790.2 643 95 51 0 597 B3EWY9 6.17e-28 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 6575 XM_029337790.2 643 95 51 0 597 B3EWY9 8.6e-24 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 6576 XM_044317328.1 622 669 308 489 499 NA NA NA NA NA NA 6577 XM_029340633.2 2314 2443 1906 2748 2405 NA NA NA NA NA NA 6578 XM_029349843.2 356 164 112 199 400 Q5EAW4 2.28e-104 Protein MCM10 homolog Xenopus laevis (African clawed frog) cellular response to DNA damage stimulus [GO:0006974]; DNA replication initiation [GO:0006270] GO:0003690; GO:0003697; GO:0005634; GO:0006270; GO:0006974; GO:0046872 6579 XM_029350960.2 0 0 0 29 0 P18130 7.36e-43 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) Bos taurus (Bovine) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of vasoconstriction [GO:0045907]; regulation of cardiac muscle contraction [GO:0055117] GO:0001996; GO:0004930; GO:0004937; GO:0005634; GO:0005737; GO:0005886; GO:0005901; GO:0007200; GO:0007204; GO:0007267; GO:0031965; GO:0043410; GO:0045907; GO:0046982; GO:0055117; GO:0071880 6580 XM_044310337.1 3 0 2 0 8 NA NA NA NA NA NA 6581 XM_044308343.1 294 189 228 212 354 F6QEU4 1.48e-60 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 6582 XM_029353141.2 3 0 0 0 10 NA NA NA NA NA NA 6583 XM_044322597.1 7 1 12 0 56 NA NA NA NA NA NA 6584 XM_029355555.2 207 139 83 54 137 NA NA NA NA NA NA 6585 XM_029350113.2 205 264 0 177 292 NA NA NA NA NA NA 6586 XM_029332321.2 202 173 163 238 220 Q61382 6.9e-65 TNF receptor-associated factor 4 (EC 2.3.2.27) (Cysteine-rich motif associated to RING and Traf domains protein 1) Mus musculus (Mouse) activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; innate immune response [GO:0045087]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein kinase activity [GO:0045860]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; respiratory gaseous exchange by respiratory system [GO:0007585]; respiratory tube development [GO:0030323] GO:0001650; GO:0005164; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0005923; GO:0006915; GO:0007250; GO:0007585; GO:0008270; GO:0016740; GO:0019901; GO:0030323; GO:0031625; GO:0031996; GO:0042802; GO:0042981; GO:0043122; GO:0043161; GO:0045087; GO:0045860; GO:0046330; GO:0048471; GO:0050699 6587 XM_029328887.2 34 17 14 16 46 NA NA NA NA NA NA 6588 XM_029335664.2 285 68 92 231 134 Q9V6X7 1.49e-107 GDP-fucose protein O-fucosyltransferase 1 (EC 2.4.1.221) (Neurotic protein) (Peptide-O-fucosyltransferase 1) (O-FucT-1) Drosophila melanogaster (Fruit fly) cell fate commitment [GO:0045165]; fucose metabolic process [GO:0006004]; Notch signaling pathway [GO:0007219]; O-glycan processing [GO:0016266]; positive regulation of endocytosis [GO:0045807]; positive regulation of Notch signaling pathway [GO:0045747]; protein O-linked fucosylation [GO:0036066]; protein O-linked glycosylation [GO:0006493]; regulation of Notch signaling pathway [GO:0008593] GO:0005112; GO:0005783; GO:0006004; GO:0006493; GO:0007219; GO:0008417; GO:0008593; GO:0016266; GO:0036066; GO:0045165; GO:0045747; GO:0045807; GO:0046922 6589 XM_044310773.1 485 362 1121 1210 735 NA NA NA NA NA NA 6590 XM_029350177.2 161 43 29 207 22 NA NA NA NA NA NA 6591 XM_044319831.1 81 0 51 65 0 Q8NHH1 9.85e-126 Tubulin polyglutamylase TTLL11 (EC 6.3.2.-) (Tubulin--tyrosine ligase-like protein 11) Homo sapiens (Human) microtubule cytoskeleton organization [GO:0000226]; microtubule severing [GO:0051013]; protein polyglutamylation [GO:0018095] GO:0000226; GO:0005524; GO:0005829; GO:0005874; GO:0005929; GO:0015631; GO:0018095; GO:0036064; GO:0046872; GO:0051013; GO:0070740 6592 XM_029351870.2 53 15 43 81 0 NA NA NA NA NA NA 6593 XM_044314264.1 0 0 0 11 0 NA NA NA NA NA NA 6594 XM_044307309.1 698 509 527 365 700 Q6GMF8 4.86e-50 Inactive rhomboid protein 1 (iRhom1) (Rhomboid family member 1) Danio rerio (Zebrafish) (Brachydanio rerio) cell migration [GO:0016477]; cell population proliferation [GO:0008283]; negative regulation of protein secretion [GO:0050709]; protein transport [GO:0015031]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of protein secretion [GO:0050708] GO:0000139; GO:0005789; GO:0008283; GO:0015031; GO:0016477; GO:0019838; GO:0042058; GO:0050708; GO:0050709; GO:0061136 6595 XM_029349076.2 68 26 55 61 33 Q96H96 2.54e-121 4-hydroxybenzoate polyprenyltransferase, mitochondrial (4-HB polyprenyltransferase) (EC 2.5.1.39) (4-hydroxybenzoate decaprenyltransferase) (COQ2 homolog) (hCOQ2) (Para-hydroxybenzoate--polyprenyltransferase) (PHB:PPT) (PHB:polyprenyltransferase) Homo sapiens (Human) glycerol metabolic process [GO:0006071]; isoprenoid biosynthetic process [GO:0008299]; ubiquinone biosynthetic process [GO:0006744] GO:0002083; GO:0004659; GO:0005743; GO:0006071; GO:0006744; GO:0008299; GO:0008412; GO:0016765; GO:0047293 6596 XM_029353100.2 20 160 28 22 68 NA NA NA NA NA NA 6597 XM_029343109.2 3081 17154 1358 18101 18025 NA NA NA NA NA NA 6598 XM_029343498.2 202 93 23 87 109 Q9QZS6 1.23e-90 Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (3-OST-3B) (Heparan sulfate 3-O-sulfotransferase 3B1) (m3-OST-3B) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; protein sulfation [GO:0006477] GO:0000139; GO:0001658; GO:0005886; GO:0006024; GO:0006477; GO:0008467; GO:0015012; GO:0033872 6599 XM_044321836.1 0 1 9 25 48 NA NA NA NA NA NA 6600 XM_044314278.1 0 0 1 10 0 NA NA NA NA NA NA 6601 XM_029341562.2 14 187 28 0 38 Q9P107 3.97e-98 GEM-interacting protein (GMIP) Homo sapiens (Human) activation of GTPase activity [GO:0090630]; intracellular signal transduction [GO:0035556]; negative regulation of GTPase activity [GO:0034260]; regulation of small GTPase mediated signal transduction [GO:0051056] GO:0005096; GO:0005654; GO:0005829; GO:0005886; GO:0034260; GO:0035556; GO:0046872; GO:0051056; GO:0090630 6602 XM_044316950.1 0 0 72 266 255 G3M4F8 9.66e-46 Octopamine receptor beta-2R (CsOA2B2) Chilo suppressalis (Asiatic rice borer moth) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cellular response to amine stimulus [GO:0071418]; octopamine signaling pathway [GO:0071927]; tyramine signaling pathway [GO:0071928] GO:0004989; GO:0005886; GO:0007189; GO:0008226; GO:0016020; GO:0071418; GO:0071927; GO:0071928 6603 XM_044309486.1 0 11 0 0 96 NA NA NA NA NA NA 6604 XM_044316661.1 0 0 0 1 6 NA NA NA NA NA NA 6605 XM_029347443.2 0 0 9 0 8 Q09575 3.93e-41 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 6606 XM_044320300.1 47 121 29 92 23 NA NA NA NA NA NA 6607 XR_006394828.1 92 0 29 109 91 NA NA NA NA NA NA 6608 XM_029356055.2 878 511 580 1010 751 NA NA NA NA NA NA 6609 XR_006395772.1 0 30 26 179 121 NA NA NA NA NA NA 6610 XM_044322220.1 3456 2305 1628 3455 3174 Q640N2 6.64e-74 ADP-ribosylation factor-like protein 13B (ADP-ribosylation factor-like protein 2-like 1) (ARL2-like protein 1) (Protein hennin) Mus musculus (Mouse) cilium assembly [GO:0060271]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; formation of radial glial scaffolds [GO:0021943]; heart looping [GO:0001947]; interneuron migration from the subpallium to the cortex [GO:0021830]; left/right axis specification [GO:0070986]; neural tube patterning [GO:0021532]; non-motile cilium assembly [GO:1905515]; receptor localization to non-motile cilium [GO:0097500]; response to lithium ion [GO:0010226]; smoothened signaling pathway [GO:0007224] GO:0001947; GO:0003924; GO:0005525; GO:0005829; GO:0005929; GO:0005930; GO:0007224; GO:0007368; GO:0009953; GO:0010226; GO:0021532; GO:0021830; GO:0021943; GO:0031514; GO:0060170; GO:0060271; GO:0070986; GO:0097500; GO:0097730; GO:1905515 6611 XM_044317937.1 32 51 13 41 7 P38571 1.17e-130 Lysosomal acid lipase/cholesteryl ester hydrolase (Acid cholesteryl ester hydrolase) (LAL) (EC 3.1.1.13) (Cholesteryl esterase) (Lipase A) (Sterol esterase) Homo sapiens (Human) cell morphogenesis [GO:0000902]; epithelial cell proliferation [GO:0050673]; homeostasis of number of cells within a tissue [GO:0048873]; inflammatory response [GO:0006954]; lipid catabolic process [GO:0016042]; low-density lipoprotein particle clearance [GO:0034383]; lung development [GO:0030324]; macrophage homeostasis [GO:0061519]; sterol metabolic process [GO:0016125]; tissue remodeling [GO:0048771] GO:0000902; GO:0001650; GO:0004771; GO:0005654; GO:0005764; GO:0005829; GO:0006954; GO:0016042; GO:0016125; GO:0016298; GO:0030324; GO:0034383; GO:0043202; GO:0043231; GO:0048771; GO:0048873; GO:0050673; GO:0061519 6612 XM_044311256.1 28 4 0 0 1 NA NA NA NA NA NA 6613 XM_029331968.2 1388 1731 1188 9657 7462 B3EWZ3 2.03e-100 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 6614 XM_029331968.2 1388 1731 1188 9657 7462 B3EWZ3 3.86e-98 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 6615 XM_029331968.2 1388 1731 1188 9657 7462 B3EWZ3 1.01e-97 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 6616 XM_029331968.2 1388 1731 1188 9657 7462 B3EWZ3 8.76e-85 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 6617 XM_029331968.2 1388 1731 1188 9657 7462 B3EWZ3 6.67e-72 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 6618 XM_029331968.2 1388 1731 1188 9657 7462 B3EWZ3 5.43e-62 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 6619 XM_029331968.2 1388 1731 1188 9657 7462 B3EWZ3 7.01e-25 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 6620 XR_006397503.1 6 66 25 117 45 NA NA NA NA NA NA 6621 XM_044310822.1 99 339 397 187 709 NA NA NA NA NA NA 6622 XM_029333067.2 156 287 273 120 313 NA NA NA NA NA NA 6623 XM_029343194.2 0 0 104 12 227 Q9QYB2 3.57e-29 Dachshund homolog 1 (Dach1) Mus musculus (Mouse) development of primary female sexual characteristics [GO:0046545]; epithelial cell proliferation [GO:0050673]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation involved in contact inhibition [GO:0060244]; negative regulation of DNA biosynthetic process [GO:2000279]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of transcription by competitive promoter binding [GO:0010944]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355]; regulation of nuclear cell cycle DNA replication [GO:0033262]; regulation of transcription by RNA polymerase II [GO:0006357]; respiratory gaseous exchange by respiratory system [GO:0007585]; suckling behavior [GO:0001967]; type B pancreatic cell proliferation [GO:0044342] GO:0000122; GO:0000977; GO:0000978; GO:0000981; GO:0001227; GO:0001967; GO:0003700; GO:0005634; GO:0005654; GO:0005667; GO:0005737; GO:0005794; GO:0005829; GO:0006355; GO:0006357; GO:0007585; GO:0010944; GO:0016607; GO:0030336; GO:0033262; GO:0044342; GO:0045892; GO:0046545; GO:0048147; GO:0050673; GO:0060244; GO:2000279 6624 XM_029338487.2 1322 917 545 1294 410 Q6DDL7 3.53e-142 Protein unc-93 homolog A (Unc-93A) Xenopus laevis (African clawed frog) NA GO:0016020 6625 XM_044312159.1 11 3 4 1 68 NA NA NA NA NA NA 6626 XM_029323468.2 294 310 344 673 384 Q9UBU9 8.15e-141 Nuclear RNA export factor 1 (Tip-associated protein) (Tip-associating protein) (mRNA export factor TAP) Homo sapiens (Human) mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; protein transport [GO:0015031] GO:0003723; GO:0003729; GO:0005634; GO:0005643; GO:0005654; GO:0005737; GO:0005829; GO:0006406; GO:0010494; GO:0015031; GO:0016607; GO:0016973; GO:0042272; GO:0042405 6627 XM_044308748.1 38 12 1 8 43 NA NA NA NA NA NA 6628 XR_006393820.1 74 44 72 301 115 NA NA NA NA NA NA 6629 XM_029354909.2 0 8 10 31 47 NA NA NA NA NA NA 6630 XR_006393574.1 170 34 23 0 27 Q9NX74 5.46e-145 tRNA-dihydrouridine(20) synthase [NAD(P)+]-like (EC 1.3.1.91) (Dihydrouridine synthase 2) (Up-regulated in lung cancer protein 8) (URLC8) (tRNA-dihydrouridine synthase 2-like) (hDUS2) Homo sapiens (Human) negative regulation of cell death [GO:0060548]; tRNA dihydrouridine synthesis [GO:0002943] GO:0000049; GO:0002943; GO:0003725; GO:0004860; GO:0005737; GO:0005783; GO:0005829; GO:0010181; GO:0017150; GO:0050660; GO:0060548; GO:0070402; GO:0102264 6631 XM_044319217.1 9 0 0 28 14 Q8VCC1 8.33e-58 15-hydroxyprostaglandin dehydrogenase [NAD(+)] (15-PGDH) (EC 1.1.1.141) (Eicosanoid/docosanoid dehydrogenase [NAD(+)]) (EC 1.1.1.-, EC 1.1.1.232) (Prostaglandin dehydrogenase 1) Mus musculus (Mouse) ductus arteriosus closure [GO:0097070]; female pregnancy [GO:0007565]; kidney development [GO:0001822]; negative regulation of cell cycle [GO:0045786]; ovulation [GO:0030728]; parturition [GO:0007567]; positive regulation of apoptotic process [GO:0043065]; positive regulation of vascular associated smooth muscle cell proliferation [GO:1904707]; prostaglandin metabolic process [GO:0006693]; regulation of prostaglandin catabolic process [GO:1905828]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; thrombin-activated receptor signaling pathway [GO:0070493]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001822; GO:0004957; GO:0005615; GO:0005654; GO:0005737; GO:0005829; GO:0006693; GO:0007179; GO:0007565; GO:0007567; GO:0016323; GO:0016404; GO:0016616; GO:0030728; GO:0032355; GO:0032496; GO:0042802; GO:0043065; GO:0045471; GO:0045786; GO:0051287; GO:0070403; GO:0070493; GO:0097070; GO:1904707; GO:1905828 6632 XM_029338174.2 468 201 275 257 40 NA NA NA NA NA NA 6633 XM_029340087.2 169 34 20 146 165 NA NA NA NA NA NA 6634 XM_029349973.2 0 1 0 25 226 NA NA NA NA NA NA 6635 XM_029339863.2 1622 1106 932 1312 1259 Q8BSY0 4.83e-169 Aspartyl/asparaginyl beta-hydroxylase (EC 1.14.11.16) (Aspartate beta-hydroxylase) (ASP beta-hydroxylase) (Peptide-aspartate beta-dioxygenase) Mus musculus (Mouse) activation of cysteine-type endopeptidase activity [GO:0097202]; activation of store-operated calcium channel activity [GO:0032237]; calcium ion homeostasis [GO:0055074]; calcium ion transmembrane transport [GO:0070588]; cell population proliferation [GO:0008283]; cellular response to calcium ion [GO:0071277]; face morphogenesis [GO:0060325]; limb morphogenesis [GO:0035108]; negative regulation of cell population proliferation [GO:0008285]; pattern specification process [GO:0007389]; peptidyl-aspartic acid hydroxylation [GO:0042264]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of proteolysis [GO:0045862]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031585]; regulation of protein depolymerization [GO:1901879]; regulation of protein stability [GO:0031647]; response to ATP [GO:0033198]; roof of mouth development [GO:0060021] GO:0005509; GO:0005737; GO:0005783; GO:0005789; GO:0005886; GO:0007389; GO:0008283; GO:0008285; GO:0010524; GO:0016020; GO:0031585; GO:0031647; GO:0032237; GO:0032541; GO:0033017; GO:0033198; GO:0035108; GO:0042264; GO:0045862; GO:0045893; GO:0051480; GO:0055074; GO:0060021; GO:0060325; GO:0062101; GO:0070588; GO:0071277; GO:0090316; GO:0097202; GO:1901879 6636 XM_029348836.2 32 14 9 16 24 NA NA NA NA NA NA 6637 XM_044313573.1 64 52 63 26 38 Q15542 1.44e-155 Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100) Homo sapiens (Human) DNA-templated transcription initiation [GO:0006352]; histone H3 acetylation [GO:0043966]; monoubiquitinated histone deubiquitination [GO:0035521]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; mRNA transcription by RNA polymerase II [GO:0042789]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription initiation at RNA polymerase II promoter [GO:0006367] GO:0000785; GO:0005634; GO:0005654; GO:0005669; GO:0006282; GO:0006352; GO:0006357; GO:0006367; GO:0006468; GO:0015629; GO:0016251; GO:0033276; GO:0035521; GO:0035522; GO:0042789; GO:0042802; GO:0043966; GO:0045893; GO:0051123; GO:0060261 6638 XM_044323502.1 24857 9828 10916 43380 39701 Q6P4Z2 6.62e-40 Collagen alpha-1(II) chain (Alpha-1 type II collagen) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005201; GO:0005576; GO:0005581; GO:0046872 6639 XM_044328362.1 8 20 29 27 10 Q9Y5N5 2.25e-71 Methyltransferase N6AMT1 (HemK methyltransferase family member 2) (M.HsaHemK2P) (Lysine N-methyltransferase 9) (EC 2.1.1.-) (Methylarsonite methyltransferase N6AMT1) (EC 2.1.1.-) (Protein N(5)-glutamine methyltransferase) (EC 2.1.1.-) Homo sapiens (Human) arsonoacetate metabolic process [GO:0018872]; chromatin organization [GO:0006325]; DNA methylation on adenine [GO:0032775]; histone lysine methylation [GO:0034968]; methylation [GO:0032259]; peptidyl-glutamine methylation [GO:0018364]; positive regulation of cell growth [GO:0030307]; toxin metabolic process [GO:0009404] GO:0003676; GO:0005634; GO:0005829; GO:0006325; GO:0008276; GO:0008757; GO:0009007; GO:0009404; GO:0018024; GO:0018364; GO:0018872; GO:0030307; GO:0030792; GO:0032259; GO:0032775; GO:0032991; GO:0034968; GO:0035657; GO:0036009; GO:1904047 6640 XM_044328271.1 144 93 57 199 189 Q8IS64 1.19e-37 Endothelin-converting enzyme homolog (ECE) (EC 3.4.24.-) Locusta migratoria (Migratory locust) proteolysis [GO:0006508] GO:0004175; GO:0004222; GO:0005886; GO:0006508; GO:0008270 6641 XM_044310147.1 476 170 246 378 370 Q80XJ3 9.58e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 6642 XM_044310147.1 476 170 246 378 370 Q80XJ3 3.53e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 6643 XM_044310147.1 476 170 246 378 370 Q80XJ3 4.08e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 6644 XM_044310147.1 476 170 246 378 370 Q80XJ3 8.93e-37 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 6645 XM_044310147.1 476 170 246 378 370 Q80XJ3 2.84e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 6646 XM_044310147.1 476 170 246 378 370 Q80XJ3 3.99e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 6647 XM_044310147.1 476 170 246 378 370 Q80XJ3 5.79e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 6648 XM_044310147.1 476 170 246 378 370 Q80XJ3 4.34e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 6649 XM_044310147.1 476 170 246 378 370 Q80XJ3 1.95e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 6650 XM_044310147.1 476 170 246 378 370 Q80XJ3 2.18e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 6651 XM_044310147.1 476 170 246 378 370 Q80XJ3 1.44e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 6652 XM_044310147.1 476 170 246 378 370 Q80XJ3 7.55e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 6653 XM_029324965.2 18 1 0 13 1 Q96AY4 6.08e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6654 XM_029340294.2 1336 1056 704 1317 1537 Q4ZQC6 3.83e-45 Peptide methionine sulfoxide reductase MsrB (EC 1.8.4.12) (Peptide-methionine (R)-S-oxide reductase) Pseudomonas syringae pv. syringae (strain B728a) protein repair [GO:0030091]; response to oxidative stress [GO:0006979] GO:0006979; GO:0008270; GO:0030091; GO:0033743 6655 XM_029325001.2 10458 34238 14922 16719 9670 Q9U9L2 9.75e-154 60S ribosomal protein L8 Anopheles gambiae (African malaria mosquito) cytoplasmic translation [GO:0002181] GO:0002181; GO:0003723; GO:0003735; GO:0019843; GO:0022625 6656 XR_006397394.1 435 289 127 384 281 NA NA NA NA NA NA 6657 XM_044312924.1 129 82 160 114 212 Q8K3Z0 2.64e-27 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 6658 XM_044328131.1 8 15 9 21 11 NA NA NA NA NA NA 6659 XR_003828009.2 591 366 275 276 180 NA NA NA NA NA NA 6660 XM_029342322.2 0 0 16 113 204 NA NA NA NA NA NA 6661 XR_006392210.1 0 0 12 0 61 NA NA NA NA NA NA 6662 XM_029339415.2 1750 1594 808 1250 1196 Q9QZN3 3.54e-98 F-box only protein 8 Mus musculus (Mouse) regulation of ARF protein signal transduction [GO:0032012]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000151; GO:0005085; GO:0006511; GO:0032012 6663 XR_006397575.1 401 253 384 338 329 NA NA NA NA NA NA 6664 XM_044317629.1 0 0 88 0 0 Q5RHH4 0 Intraflagellar transport protein 172 homolog Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; intraciliary transport [GO:0042073]; photoreceptor cell maintenance [GO:0045494]; pronephros development [GO:0048793]; regulation of TOR signaling [GO:0032006]; retina development in camera-type eye [GO:0060041] GO:0005929; GO:0005930; GO:0030992; GO:0032006; GO:0036064; GO:0042073; GO:0045494; GO:0048793; GO:0060041; GO:0060271 6665 XM_029335155.2 305 326 164 320 174 Q0VA03 1.4e-177 Polycomb protein suz12 (Suppressor of zeste 12 protein homolog) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) chromatin organization [GO:0006325] GO:0006325; GO:0035098; GO:0046872 6666 XR_006396432.1 0 0 0 0 23 Q8K2X2 1.94e-23 RNA-binding protein 48 Mus musculus (Mouse) NA GO:0003723; GO:0005654 6667 XM_044307910.1 0 16 0 31 0 NA NA NA NA NA NA 6668 XM_029329755.2 65 14 48 32 69 NA NA NA NA NA NA 6669 XM_044308315.1 47 95 359 364 914 NA NA NA NA NA NA 6670 XM_029348685.2 49 89 31 81 52 Q96CG8 1.34e-41 Collagen triple helix repeat-containing protein 1 Homo sapiens (Human) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005576; GO:0005581; GO:0005615; GO:0016477; GO:0016528; GO:0017147; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0062023; GO:0090090; GO:0090103; GO:0090177 6671 XM_044316364.1 21 23 1 12 30 NA NA NA NA NA NA 6672 XR_003824235.2 26 4 6 10 30 NA NA NA NA NA NA 6673 XM_044319949.1 225 36 123 68 233 Q9Z136 4.34e-54 Hamartin (Tuberous sclerosis 1 protein homolog) Rattus norvegicus (Rat) activation of GTPase activity [GO:0090630]; adaptive immune response [GO:0002250]; adult locomotory behavior [GO:0008344]; associative learning [GO:0008306]; cardiac muscle cell differentiation [GO:0055007]; cell population proliferation [GO:0008283]; cell projection organization [GO:0030030]; cell-matrix adhesion [GO:0007160]; cellular response to oxygen-glucose deprivation [GO:0090650]; cerebral cortex development [GO:0021987]; glucose import [GO:0046323]; hippocampus development [GO:0021766]; kidney development [GO:0001822]; memory T cell differentiation [GO:0043379]; myelination [GO:0042552]; negative regulation of ATP-dependent activity [GO:0032780]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of macroautophagy [GO:0016242]; negative regulation of neuron projection development [GO:0010977]; negative regulation of oxidative stress-induced neuron death [GO:1903204]; negative regulation of TOR signaling [GO:0032007]; negative regulation of translation [GO:0017148]; nervous system development [GO:0007399]; neural tube closure [GO:0001843]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of macroautophagy [GO:0016239]; positive regulation of stress fiber assembly [GO:0051496]; potassium ion transport [GO:0006813]; protein stabilization [GO:0050821]; regulation of cell cycle [GO:0051726]; regulation of cell-matrix adhesion [GO:0001952]; regulation of focal adhesion assembly [GO:0051893]; regulation of neuron death [GO:1901214]; regulation of phosphoprotein phosphatase activity [GO:0043666]; regulation of protein kinase activity [GO:0045859]; regulation of stress fiber assembly [GO:0051492]; regulation of translation [GO:0006417]; response to insulin [GO:0032868]; response to nutrient levels [GO:0031667]; response to peptide [GO:1901652]; rRNA export from nucleus [GO:0006407]; synapse organization [GO:0050808] GO:0001822; GO:0001843; GO:0001952; GO:0002250; GO:0005634; GO:0005737; GO:0005811; GO:0005829; GO:0005856; GO:0005884; GO:0005938; GO:0006407; GO:0006417; GO:0006813; GO:0007160; GO:0007399; GO:0008283; GO:0008285; GO:0008306; GO:0008344; GO:0010977; GO:0014069; GO:0016020; GO:0016239; GO:0016242; GO:0017148; GO:0021766; GO:0021987; GO:0030027; GO:0030030; GO:0030426; GO:0030544; GO:0031667; GO:0032007; GO:0032780; GO:0032794; GO:0032868; GO:0032991; GO:0033596; GO:0034260; GO:0042030; GO:0042552; GO:0042995; GO:0043231; GO:0043379; GO:0043666; GO:0044877; GO:0045792; GO:0045859; GO:0046323; GO:0047485; GO:0048471; GO:0050808; GO:0050821; GO:0051087; GO:0051492; GO:0051496; GO:0051726; GO:0051879; GO:0051893; GO:0051894; GO:0055007; GO:0090630; GO:0090650; GO:0101031; GO:1901214; GO:1901652; GO:1903204 6674 XM_044319949.1 225 36 123 68 233 Q9Z136 7.54e-32 Hamartin (Tuberous sclerosis 1 protein homolog) Rattus norvegicus (Rat) activation of GTPase activity [GO:0090630]; adaptive immune response [GO:0002250]; adult locomotory behavior [GO:0008344]; associative learning [GO:0008306]; cardiac muscle cell differentiation [GO:0055007]; cell population proliferation [GO:0008283]; cell projection organization [GO:0030030]; cell-matrix adhesion [GO:0007160]; cellular response to oxygen-glucose deprivation [GO:0090650]; cerebral cortex development [GO:0021987]; glucose import [GO:0046323]; hippocampus development [GO:0021766]; kidney development [GO:0001822]; memory T cell differentiation [GO:0043379]; myelination [GO:0042552]; negative regulation of ATP-dependent activity [GO:0032780]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of macroautophagy [GO:0016242]; negative regulation of neuron projection development [GO:0010977]; negative regulation of oxidative stress-induced neuron death [GO:1903204]; negative regulation of TOR signaling [GO:0032007]; negative regulation of translation [GO:0017148]; nervous system development [GO:0007399]; neural tube closure [GO:0001843]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of macroautophagy [GO:0016239]; positive regulation of stress fiber assembly [GO:0051496]; potassium ion transport [GO:0006813]; protein stabilization [GO:0050821]; regulation of cell cycle [GO:0051726]; regulation of cell-matrix adhesion [GO:0001952]; regulation of focal adhesion assembly [GO:0051893]; regulation of neuron death [GO:1901214]; regulation of phosphoprotein phosphatase activity [GO:0043666]; regulation of protein kinase activity [GO:0045859]; regulation of stress fiber assembly [GO:0051492]; regulation of translation [GO:0006417]; response to insulin [GO:0032868]; response to nutrient levels [GO:0031667]; response to peptide [GO:1901652]; rRNA export from nucleus [GO:0006407]; synapse organization [GO:0050808] GO:0001822; GO:0001843; GO:0001952; GO:0002250; GO:0005634; GO:0005737; GO:0005811; GO:0005829; GO:0005856; GO:0005884; GO:0005938; GO:0006407; GO:0006417; GO:0006813; GO:0007160; GO:0007399; GO:0008283; GO:0008285; GO:0008306; GO:0008344; GO:0010977; GO:0014069; GO:0016020; GO:0016239; GO:0016242; GO:0017148; GO:0021766; GO:0021987; GO:0030027; GO:0030030; GO:0030426; GO:0030544; GO:0031667; GO:0032007; GO:0032780; GO:0032794; GO:0032868; GO:0032991; GO:0033596; GO:0034260; GO:0042030; GO:0042552; GO:0042995; GO:0043231; GO:0043379; GO:0043666; GO:0044877; GO:0045792; GO:0045859; GO:0046323; GO:0047485; GO:0048471; GO:0050808; GO:0050821; GO:0051087; GO:0051492; GO:0051496; GO:0051726; GO:0051879; GO:0051893; GO:0051894; GO:0055007; GO:0090630; GO:0090650; GO:0101031; GO:1901214; GO:1901652; GO:1903204 6675 XM_044307128.1 32 2 7 11 0 NA NA NA NA NA NA 6676 XM_029345611.2 21 4 5 0 0 NA NA NA NA NA NA 6677 XM_029329886.2 29 0 0 0 0 O31463 5.5e-48 Homocysteine S-methyltransferase YbgG (EC 2.1.1.10) (S-methylmethionine:homocysteine methyltransferase) Bacillus subtilis (strain 168) methionine biosynthetic process [GO:0009086]; methylation [GO:0032259]; S-methylmethionine cycle [GO:0033528] GO:0008270; GO:0008898; GO:0009086; GO:0032259; GO:0033528; GO:0061627 6678 XM_029324165.2 1669 949 935 782 1049 NA NA NA NA NA NA 6679 XM_029331511.2 360 0 0 108 0 Q13627 0 Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.11.23) (EC 2.7.12.1) (Dual specificity YAK1-related kinase) (HP86) (Protein kinase minibrain homolog) (MNBH) (hMNB) Homo sapiens (Human) amyloid-beta formation [GO:0034205]; circadian rhythm [GO:0007623]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of DNA methylation-dependent heterochromatin formation [GO:0090310]; negative regulation of microtubule polymerization [GO:0031115]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; nervous system development [GO:0007399]; peptidyl-serine autophosphorylation [GO:0036289]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of protein deacetylation [GO:0090312]; positive regulation of RNA splicing [GO:0033120]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468] GO:0003713; GO:0003779; GO:0004672; GO:0004674; GO:0004712; GO:0004713; GO:0004715; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005856; GO:0006468; GO:0007399; GO:0007623; GO:0008092; GO:0008353; GO:0015631; GO:0016607; GO:0018105; GO:0018107; GO:0018108; GO:0030424; GO:0030425; GO:0031115; GO:0033120; GO:0034205; GO:0036289; GO:0038083; GO:0042802; GO:0043518; GO:0043621; GO:0045893; GO:0046777; GO:0048025; GO:0048156; GO:0050321; GO:0090310; GO:0090312; GO:0106310; GO:0140857; GO:1990904 6680 XM_029340120.2 463 312 226 1212 850 B3EWZ5 9.9e-87 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6681 XM_029340120.2 463 312 226 1212 850 B3EWZ5 7.55e-76 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6682 XM_029340120.2 463 312 226 1212 850 B3EWZ5 1.3e-75 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6683 XM_029340120.2 463 312 226 1212 850 B3EWZ5 1.48e-72 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6684 XM_029340120.2 463 312 226 1212 850 B3EWZ5 1.43e-71 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6685 XM_029340120.2 463 312 226 1212 850 B3EWZ5 1.77e-71 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6686 XM_029340120.2 463 312 226 1212 850 B3EWZ5 4.61e-70 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6687 XM_029340120.2 463 312 226 1212 850 B3EWZ5 5.67e-69 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6688 XM_029340120.2 463 312 226 1212 850 B3EWZ5 2.27e-68 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6689 XM_029340120.2 463 312 226 1212 850 B3EWZ5 4.23e-68 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6690 XM_029340120.2 463 312 226 1212 850 B3EWZ5 4.83e-67 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6691 XM_029340120.2 463 312 226 1212 850 B3EWZ5 1.26e-66 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6692 XM_029340120.2 463 312 226 1212 850 B3EWZ5 1.77e-61 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6693 XM_029340120.2 463 312 226 1212 850 B3EWZ5 1.56e-59 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6694 XM_029340120.2 463 312 226 1212 850 B3EWZ5 1.6e-48 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6695 XM_029340120.2 463 312 226 1212 850 B3EWZ5 6.74e-40 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6696 XM_029340120.2 463 312 226 1212 850 B3EWZ5 2.88e-38 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6697 XM_029340120.2 463 312 226 1212 850 B3EWZ5 1.5e-23 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6698 XM_044326566.1 0 0 0 8 0 NA NA NA NA NA NA 6699 XM_044318520.1 0 42 0 0 47 P0CI65 9.19e-52 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 6700 XM_044318520.1 0 42 0 0 47 P0CI65 1.47e-49 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 6701 XM_044318520.1 0 42 0 0 47 P0CI65 2.73e-49 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 6702 XM_044318520.1 0 42 0 0 47 P0CI65 5.55e-49 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 6703 XM_044318520.1 0 42 0 0 47 P0CI65 1.79e-46 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 6704 XM_044318520.1 0 42 0 0 47 P0CI65 1.92e-46 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 6705 XM_044318520.1 0 42 0 0 47 P0CI65 2.09e-42 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 6706 XM_044318520.1 0 42 0 0 47 P0CI65 4.17e-38 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 6707 XM_044326402.1 32 23 0 0 0 P30975 3.62e-24 Tachykinin-like peptides receptor 99D (Tachykinin-like receptor at 99D) (dTKR) Drosophila melanogaster (Fruit fly) detection of chemical stimulus involved in sensory perception of smell [GO:0050911]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; neuropeptide signaling pathway [GO:0007218]; olfactory behavior [GO:0042048]; positive regulation of sensory perception of pain [GO:1904058]; tachykinin receptor signaling pathway [GO:0007217] GO:0004995; GO:0005886; GO:0007186; GO:0007217; GO:0007218; GO:0008188; GO:0016020; GO:0042048; GO:0050805; GO:0050911; GO:1904058 6708 XM_029350497.2 0 81 0 4 101 NA NA NA NA NA NA 6709 XM_044325797.1 0 0 0 8 31 Q09575 2.02e-50 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 6710 XM_044329136.1 105 18 135 259 149 NA NA NA NA NA NA 6711 XM_044327613.1 312 298 131 336 262 NA NA NA NA NA NA 6712 XR_006392332.1 1069 18 81 195 206 NA NA NA NA NA NA 6713 XM_044310779.1 490 290 4 296 202 NA NA NA NA NA NA 6714 XR_006396556.1 42 42 18 39 38 NA NA NA NA NA NA 6715 XM_044308209.1 1489 1104 772 2338 1255 NA NA NA NA NA NA 6716 XM_044323553.1 0 7 0 0 0 E1BD59 1.44e-21 E3 ubiquitin-protein ligase TRIM56 (EC 2.3.2.27) (Tripartite motif-containing protein 56) Bos taurus (Bovine) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of interferon-beta production [GO:0032728]; protein K63-linked ubiquitination [GO:0070534]; response to type I interferon [GO:0034340] GO:0000785; GO:0004842; GO:0005654; GO:0005737; GO:0008270; GO:0032728; GO:0034340; GO:0045087; GO:0045893; GO:0051607; GO:0061630; GO:0070534 6717 XR_006396198.1 770 597 394 699 595 P53452 2.37e-35 D(1)-like dopamine receptor Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; vasodilation [GO:0042311] GO:0004930; GO:0004952; GO:0005886; GO:0007189; GO:0042311; GO:0045202 6718 XR_006396198.1 770 597 394 699 595 P53452 2.37e-35 D(1)-like dopamine receptor Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; vasodilation [GO:0042311] GO:0004930; GO:0004952; GO:0005886; GO:0007189; GO:0042311; GO:0045202 6719 XM_029340292.2 986 729 437 851 729 Q8NKE2 2.7e-74 Alternative oxidase, mitochondrial (EC 1.-.-.-) Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii) NA GO:0005743; GO:0009916; GO:0046872; GO:0070469 6720 XR_003824444.2 8 0 0 2 0 NA NA NA NA NA NA 6721 XR_006395270.1 5 2 10 0 26 Q9R062 2.16e-21 Glycogenin-1 (GN-1) (GN1) (EC 2.4.1.186) Mus musculus (Mouse) glycogen biosynthetic process [GO:0005978] GO:0005536; GO:0005978; GO:0008466; GO:0016757; GO:0030145; GO:0042803; GO:0102751 6722 XR_006395270.1 5 2 10 0 26 Q9R062 2.16e-21 Glycogenin-1 (GN-1) (GN1) (EC 2.4.1.186) Mus musculus (Mouse) glycogen biosynthetic process [GO:0005978] GO:0005536; GO:0005978; GO:0008466; GO:0016757; GO:0030145; GO:0042803; GO:0102751 6723 XR_006393380.1 12 9 26 29 9 NA NA NA NA NA NA 6724 XM_029330281.2 577 524 440 435 445 Q8NBA8 5.34e-59 tRNA-uridine aminocarboxypropyltransferase 2 (EC 2.5.1.25) (DTW domain-containing protein 2) Homo sapiens (Human) tRNA modification [GO:0006400] GO:0005634; GO:0005737; GO:0006400; GO:0016432 6725 XR_006391828.1 16 0 0 23 19 NA NA NA NA NA NA 6726 XR_006396066.1 543 594 317 847 1225 NA NA NA NA NA NA 6727 XR_003827199.2 15 0 9 3 7 NA NA NA NA NA NA 6728 XR_006393015.1 40 79 24 21 96 A6NED2 4.32e-38 RCC1 domain-containing protein 1 Homo sapiens (Human) chromatin organization [GO:0006325] GO:0005694; GO:0005829; GO:0005886; GO:0006325 6729 XR_006396090.1 0 21 0 0 34 NA NA NA NA NA NA 6730 XM_029331510.2 128 179 95 167 102 NA NA NA NA NA NA 6731 XM_029351605.2 4035 4568 2113 2801 1897 NA NA NA NA NA NA 6732 XM_029352005.2 132 69 36 80 31 NA NA NA NA NA NA 6733 XM_029348490.2 54 94 52 111 176 NA NA NA NA NA NA 6734 XR_006395920.1 459 310 265 606 908 NA NA NA NA NA NA 6735 XR_003825516.2 104 40 70 44 46 NA NA NA NA NA NA 6736 XM_044309435.1 17 1 2 0 43 NA NA NA NA NA NA 6737 XM_029356412.2 214 215 84 203 106 NA NA NA NA NA NA 6738 XM_029329997.2 14 159 254 178 73 NA NA NA NA NA NA 6739 XR_006397839.1 149 137 61 81 92 NA NA NA NA NA NA 6740 XM_029341035.2 2178 1395 802 2280 2129 Q9UKV3 3.31e-28 Apoptotic chromatin condensation inducer in the nucleus (Acinus) Homo sapiens (Human) apoptotic chromosome condensation [GO:0030263]; erythrocyte differentiation [GO:0030218]; mRNA processing [GO:0006397]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of apoptotic process [GO:0043065]; positive regulation of monocyte differentiation [GO:0045657]; RNA splicing [GO:0008380] GO:0003676; GO:0003723; GO:0005634; GO:0005654; GO:0005829; GO:0005886; GO:0006397; GO:0008380; GO:0016607; GO:0016887; GO:0019899; GO:0030218; GO:0030263; GO:0043065; GO:0045657; GO:0048025; GO:0061574 6741 XM_044322533.1 0 29 0 6 174 NA NA NA NA NA NA 6742 XM_029323458.2 31 13 88 24 268 NA NA NA NA NA NA 6743 XM_029332690.2 662 309 234 258 400 NA NA NA NA NA NA 6744 XM_044316861.1 64 135 36 182 382 O08762 2.29e-26 Neurotrypsin (EC 3.4.21.-) (Brain-specific serine protease 3) (BSSP-3) (Motopsin) (Serine protease 12) Mus musculus (Mouse) exocytosis [GO:0006887]; proteolysis [GO:0006508]; zymogen activation [GO:0031638] GO:0004252; GO:0005044; GO:0005886; GO:0006508; GO:0006887; GO:0008233; GO:0030424; GO:0030425; GO:0031410; GO:0031638; GO:0043083; GO:0043195; GO:0045202 6745 XM_044316861.1 64 135 36 182 382 O08762 4.99e-23 Neurotrypsin (EC 3.4.21.-) (Brain-specific serine protease 3) (BSSP-3) (Motopsin) (Serine protease 12) Mus musculus (Mouse) exocytosis [GO:0006887]; proteolysis [GO:0006508]; zymogen activation [GO:0031638] GO:0004252; GO:0005044; GO:0005886; GO:0006508; GO:0006887; GO:0008233; GO:0030424; GO:0030425; GO:0031410; GO:0031638; GO:0043083; GO:0043195; GO:0045202 6746 XM_044325103.1 108 5 95 13 369 NA NA NA NA NA NA 6747 XM_044319698.1 32 7 1 34 11 E7FAM5 1.68e-79 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 6748 XM_044310482.1 42 449 2 190 0 NA NA NA NA NA NA 6749 XM_029337029.2 47 0 0 0 67 NA NA NA NA NA NA 6750 XM_029347778.2 69 10 65 62 180 Q3V2A7 4e-28 Glutamine-rich protein 2 Mus musculus (Mouse) cell projection assembly [GO:0030031]; flagellated sperm motility [GO:0030317]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059] GO:0005634; GO:0005737; GO:0030031; GO:0030317; GO:0031965; GO:0036126; GO:2000059 6751 XM_029330031.2 73 9 41 19 95 O18276 5.69e-59 Gamma-aminobutyric acid receptor subunit beta (GABA(A) receptor subunit beta) Caenorhabditis elegans chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165] GO:0004890; GO:0005230; GO:0005231; GO:0005254; GO:0005886; GO:0006811; GO:0007165; GO:0007268; GO:0030594; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:1902476; GO:1902711; GO:1904315 6752 XM_029348220.2 5 0 0 30 3 NA NA NA NA NA NA 6753 XM_029331456.2 4984 5128 2223 3024 3484 Q6TAW2 5.12e-32 Stress-associated endoplasmic reticulum protein 2 (Ribosome-associated membrane protein RAMP4-2) Mus musculus (Mouse) endoplasmic reticulum unfolded protein response [GO:0030968]; protein glycosylation [GO:0006486]; protein transport [GO:0015031] GO:0005789; GO:0006486; GO:0015031; GO:0030968 6754 XM_029352098.2 0 20 4 24 24 NA NA NA NA NA NA 6755 XM_044323946.1 498 588 305 169 271 Q9CXI3 2.12e-119 DBH-like monooxygenase protein 1 (EC 1.14.17.-) (DBH-related protein) (Monooxygenase X) Mus musculus (Mouse) dopamine catabolic process [GO:0042420]; norepinephrine biosynthetic process [GO:0042421]; octopamine biosynthetic process [GO:0006589] GO:0004500; GO:0005507; GO:0005615; GO:0005789; GO:0006589; GO:0030667; GO:0042420; GO:0042421 6756 XM_044328960.1 24 0 0 0 89 NA NA NA NA NA NA 6757 XM_044324655.1 0 369 0 17 0 O15068 9.02e-153 Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2-transforming sequence-like protein) Homo sapiens (Human) intracellular signal transduction [GO:0035556]; positive regulation of Rho protein signal transduction [GO:0035025]; regulation of small GTPase mediated signal transduction [GO:0051056] GO:0005085; GO:0005615; GO:0005737; GO:0005829; GO:0005886; GO:0012505; GO:0019898; GO:0031234; GO:0035025; GO:0035091; GO:0035556; GO:0051056 6758 XM_044313435.1 0 192 0 0 0 NA NA NA NA NA NA 6759 XM_044323479.1 907 72 60 434 44 A4IFW2 0 Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) Danio rerio (Zebrafish) (Brachydanio rerio) peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; sensory neuron axon guidance [GO:0097374]; synaptic membrane adhesion [GO:0099560] GO:0004725; GO:0006470; GO:0008201; GO:0016020; GO:0035335; GO:0097374; GO:0099560 6760 XM_044323479.1 907 72 60 434 44 A4IFW2 9.87e-57 Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) Danio rerio (Zebrafish) (Brachydanio rerio) peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; sensory neuron axon guidance [GO:0097374]; synaptic membrane adhesion [GO:0099560] GO:0004725; GO:0006470; GO:0008201; GO:0016020; GO:0035335; GO:0097374; GO:0099560 6761 XM_044323479.1 907 72 60 434 44 A4IFW2 6.9e-55 Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) Danio rerio (Zebrafish) (Brachydanio rerio) peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; sensory neuron axon guidance [GO:0097374]; synaptic membrane adhesion [GO:0099560] GO:0004725; GO:0006470; GO:0008201; GO:0016020; GO:0035335; GO:0097374; GO:0099560 6762 XM_044323479.1 907 72 60 434 44 A4IFW2 9.68e-54 Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) Danio rerio (Zebrafish) (Brachydanio rerio) peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; sensory neuron axon guidance [GO:0097374]; synaptic membrane adhesion [GO:0099560] GO:0004725; GO:0006470; GO:0008201; GO:0016020; GO:0035335; GO:0097374; GO:0099560 6763 XM_044323479.1 907 72 60 434 44 A4IFW2 8.84e-33 Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) Danio rerio (Zebrafish) (Brachydanio rerio) peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; sensory neuron axon guidance [GO:0097374]; synaptic membrane adhesion [GO:0099560] GO:0004725; GO:0006470; GO:0008201; GO:0016020; GO:0035335; GO:0097374; GO:0099560 6764 XM_029339154.2 10 29 27 32 38 A7SIM4 0 Hapless 2 (Generative cell specific 1) Nematostella vectensis (Starlet sea anemone) single fertilization [GO:0007338] GO:0005886; GO:0007338; GO:0008289 6765 XM_029334708.2 35 19 57 69 53 P53791 0 Sodium/glucose cotransporter 1 (Na(+)/glucose cotransporter 1) (High affinity sodium-glucose cotransporter) (Solute carrier family 5 member 1) Ovis aries (Sheep) glucose import across plasma membrane [GO:0098708]; intestinal D-glucose absorption [GO:0001951]; renal glucose absorption [GO:0035623]; response to inorganic substance [GO:0010035]; sodium ion import across plasma membrane [GO:0098719]; transepithelial water transport [GO:0035377]; transport across blood-brain barrier [GO:0150104] GO:0001951; GO:0005372; GO:0005412; GO:0005769; GO:0010035; GO:0015151; GO:0015371; GO:0016324; GO:0035377; GO:0035623; GO:0048471; GO:0055056; GO:0098708; GO:0098719; GO:0150104 6766 XM_044314625.1 0 33 2 21 0 Q7RTR2 2.8e-72 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 6767 XM_044314625.1 0 33 2 21 0 Q7RTR2 1.15e-71 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 6768 XM_044314625.1 0 33 2 21 0 Q7RTR2 4.28e-64 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 6769 XM_044314625.1 0 33 2 21 0 Q7RTR2 1.49e-59 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 6770 XM_044314625.1 0 33 2 21 0 Q7RTR2 7.24e-58 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 6771 XM_044314625.1 0 33 2 21 0 Q7RTR2 1.78e-40 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 6772 XM_044314625.1 0 33 2 21 0 Q7RTR2 1.67e-34 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 6773 XM_044327013.1 16 0 65 40 96 NA NA NA NA NA NA 6774 XM_029344007.2 1379 1052 856 1437 1275 P35790 9.42e-86 Choline kinase alpha (CK) (EC 2.7.1.32) (CHETK-alpha) (Ethanolamine kinase) (EK) (EC 2.7.1.82) Homo sapiens (Human) CDP-choline pathway [GO:0006657]; cellular response to glucose starvation [GO:0042149]; lipid droplet disassembly [GO:1905691]; lipid metabolic process [GO:0006629]; lipid transport [GO:0006869]; phosphatidylcholine biosynthetic process [GO:0006656]; phosphatidylethanolamine biosynthetic process [GO:0006646] GO:0004103; GO:0004104; GO:0004305; GO:0004713; GO:0005524; GO:0005737; GO:0005811; GO:0005829; GO:0006629; GO:0006646; GO:0006656; GO:0006657; GO:0006869; GO:0042149; GO:0042803; GO:1905691 6775 XM_044311566.1 536 339 299 470 668 Q3U3V8 2.51e-38 X-ray radiation resistance-associated protein 1 Mus musculus (Mouse) response to X-ray [GO:0010165] GO:0005634; GO:0005654; GO:0005737; GO:0010165; GO:0016604 6776 XR_006394312.1 19 31 12 45 137 NA NA NA NA NA NA 6777 XM_044325754.1 0 0 0 21 11 NA NA NA NA NA NA 6778 XM_029335807.2 37 46 46 27 82 Q9JK91 0 DNA mismatch repair protein Mlh1 (MutL protein homolog 1) Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; female meiosis chromosome segregation [GO:0016321]; homologous chromosome pairing at meiosis [GO:0007129]; homologous chromosome segregation [GO:0045143]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; isotype switching [GO:0045190]; male meiosis chromosome segregation [GO:0007060]; male meiotic nuclear division [GO:0007140]; meiotic cell cycle [GO:0051321]; meiotic chromosome segregation [GO:0045132]; meiotic metaphase I plate congression [GO:0043060]; meiotic spindle midzone assembly [GO:0051257]; meiotic telomere clustering [GO:0045141]; mismatch repair [GO:0006298]; negative regulation of mitotic recombination [GO:0045950]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; oogenesis [GO:0048477]; positive regulation of isotype switching to IgA isotypes [GO:0048298]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; reciprocal meiotic recombination [GO:0007131]; resolution of meiotic recombination intermediates [GO:0000712]; response to bacterium [GO:0009617]; somatic hypermutation of immunoglobulin genes [GO:0016446]; somatic recombination of immunoglobulin gene segments [GO:0016447]; somatic recombination of immunoglobulin genes involved in immune response [GO:0002204]; spermatogenesis [GO:0007283] GO:0000289; GO:0000712; GO:0000793; GO:0000794; GO:0000795; GO:0001673; GO:0002204; GO:0003682; GO:0003697; GO:0005524; GO:0005634; GO:0005654; GO:0005694; GO:0005712; GO:0005715; GO:0006281; GO:0006298; GO:0006303; GO:0006974; GO:0007060; GO:0007129; GO:0007131; GO:0007140; GO:0007283; GO:0008630; GO:0009617; GO:0016321; GO:0016446; GO:0016447; GO:0016887; GO:0019899; GO:0032137; GO:0032300; GO:0032389; GO:0032407; GO:0043060; GO:0045132; GO:0045141; GO:0045143; GO:0045190; GO:0045950; GO:0048298; GO:0048304; GO:0048477; GO:0051257; GO:0051321; GO:0140664 6779 XM_044307079.1 829 535 0 579 785 Q9BUD6 5.81e-32 Spondin-2 (Differentially expressed in cancerous and non-cancerous lung cells 1) (DIL-1) (Mindin) Homo sapiens (Human) cell adhesion [GO:0007155]; cellular response to lipopolysaccharide [GO:0071222]; defense response to fungus [GO:0050832]; defense response to virus [GO:0051607]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; mast cell mediated immunity [GO:0002448]; opsonization [GO:0008228]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of tumor necrosis factor production [GO:0032760] GO:0001530; GO:0002448; GO:0003823; GO:0007155; GO:0008228; GO:0031012; GO:0032755; GO:0032760; GO:0043152; GO:0045087; GO:0046872; GO:0050832; GO:0051607; GO:0060907; GO:0070062; GO:0071222 6780 XM_044307079.1 829 535 0 579 785 Q9BUD6 5e-22 Spondin-2 (Differentially expressed in cancerous and non-cancerous lung cells 1) (DIL-1) (Mindin) Homo sapiens (Human) cell adhesion [GO:0007155]; cellular response to lipopolysaccharide [GO:0071222]; defense response to fungus [GO:0050832]; defense response to virus [GO:0051607]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; mast cell mediated immunity [GO:0002448]; opsonization [GO:0008228]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of tumor necrosis factor production [GO:0032760] GO:0001530; GO:0002448; GO:0003823; GO:0007155; GO:0008228; GO:0031012; GO:0032755; GO:0032760; GO:0043152; GO:0045087; GO:0046872; GO:0050832; GO:0051607; GO:0060907; GO:0070062; GO:0071222 6781 XM_044315563.1 29 0 0 38 0 Q4R5Y0 1.19e-34 Uncharacterized protein CFAP68 (cilia and flagella associated protein 68) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0005634 6782 XM_029349954.2 328 176 116 225 620 A7MB54 3.33e-24 H2.0-like homeobox protein (Homeobox protein HLX1) Bos taurus (Bovine) embryonic digestive tract morphogenesis [GO:0048557]; enteric nervous system development [GO:0048484]; epithelial cell proliferation [GO:0050673]; liver development [GO:0001889]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; organ growth [GO:0035265]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of organ growth [GO:0046622]; positive regulation of T-helper 1 cell differentiation [GO:0045627]; skeletal muscle tissue development [GO:0007519]; T-helper 1 cell differentiation [GO:0045063]; T-helper 2 cell differentiation [GO:0045064] GO:0000981; GO:0001889; GO:0005634; GO:0007519; GO:0035265; GO:0043565; GO:0045063; GO:0045064; GO:0045627; GO:0045629; GO:0046622; GO:0048484; GO:0048557; GO:0050673; GO:0050679 6783 XM_044324805.1 1071 1606 1472 1001 486 NA NA NA NA NA NA 6784 XM_029340581.2 451 86 75 54 75 P30549 8.03e-36 Substance-K receptor (SKR) (NK-2 receptor) (NK-2R) (Neurokinin A receptor) (Tachykinin receptor 2) Mus musculus (Mouse) intestine smooth muscle contraction [GO:0014827]; negative regulation of luteinizing hormone secretion [GO:0033685]; operant conditioning [GO:0035106]; positive regulation of acetylcholine secretion, neurotransmission [GO:0014057]; positive regulation of flagellated sperm motility [GO:1902093]; positive regulation of ion transport [GO:0043270]; positive regulation of uterine smooth muscle contraction [GO:0070474]; positive regulation of vascular permeability [GO:0043117]; prolactin secretion [GO:0070459]; regulation of uterine smooth muscle contraction [GO:0070472]; response to electrical stimulus [GO:0051602] GO:0004995; GO:0005886; GO:0014057; GO:0014827; GO:0016020; GO:0016497; GO:0033685; GO:0035106; GO:0036126; GO:0043117; GO:0043270; GO:0051602; GO:0061827; GO:0070459; GO:0070472; GO:0070474; GO:0097225; GO:1902093 6785 XM_029349528.2 281 250 120 201 230 Q8JFW4 2.95e-76 Probable inactive tRNA-specific adenosine deaminase-like protein 3 (tRNA-specific adenosine-34 deaminase subunit adat3) Danio rerio (Zebrafish) (Brachydanio rerio) tRNA processing [GO:0008033] GO:0003824; GO:0005634; GO:0005737; GO:0008033; GO:0046872 6786 XM_029348967.2 0 0 60 0 27 F1R8P4 3.12e-94 Glycine receptor subunit alpha-2 Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0004888; GO:0005254; GO:0016594; GO:0016933; GO:0022824; GO:0034707; GO:0042995; GO:0045211; GO:0046872 6787 XM_029343178.2 48 0 6 33 0 NA NA NA NA NA NA 6788 XM_044310675.1 1171 1476 648 757 871 Q12834 3.96e-155 Cell division cycle protein 20 homolog (p55CDC) Homo sapiens (Human) anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell differentiation [GO:0030154]; cell division [GO:0051301]; mitotic sister chromatid cohesion [GO:0007064]; mitotic spindle assembly [GO:0090307]; mitotic spindle assembly checkpoint signaling [GO:0007094]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; nervous system development [GO:0007399]; positive regulation of anaphase-promoting complex-dependent catabolic process [GO:1905786]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of synapse maturation [GO:0090129]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; protein ubiquitination [GO:0016567]; regulation of dendrite development [GO:0050773]; regulation of meiotic cell cycle [GO:0051445]; regulation of meiotic nuclear division [GO:0040020]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005654; GO:0005680; GO:0005813; GO:0005819; GO:0005829; GO:0007064; GO:0007094; GO:0007346; GO:0007399; GO:0008022; GO:0008284; GO:0010997; GO:0016567; GO:0019899; GO:0030154; GO:0031145; GO:0031915; GO:0033597; GO:0040020; GO:0042826; GO:0048471; GO:0050773; GO:0051301; GO:0051444; GO:0051445; GO:0090129; GO:0090307; GO:1904668; GO:1905786; GO:1990757 6789 XR_006392326.1 21 0 0 17 0 NA NA NA NA NA NA 6790 XM_044309731.1 52 12 50 0 81 NA NA NA NA NA NA 6791 XR_003823508.2 62 74 68 65 66 NA NA NA NA NA NA 6792 XM_044324773.1 0 0 0 40 1 NA NA NA NA NA NA 6793 XM_044308048.1 233 6 96 225 120 NA NA NA NA NA NA 6794 XM_044325941.1 26 4 15 18 5 E9Q5R7 5.03e-38 NACHT, LRR and PYD domains-containing protein 12 (Monarch-1) (PYRIN-containing APAF1-like protein 7) (PYPAF7) Mus musculus (Mouse) cellular response to cytokine stimulus [GO:0071345]; dendritic cell migration [GO:0036336]; ERK1 and ERK2 cascade [GO:0070371]; negative regulation of cytokine production [GO:0001818]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of signal transduction [GO:0009968]; negative regulation of Toll signaling pathway [GO:0045751]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of inflammatory response [GO:0050727] GO:0001818; GO:0005524; GO:0005737; GO:0009968; GO:0031953; GO:0032088; GO:0032692; GO:0032715; GO:0036336; GO:0038061; GO:0043122; GO:0043124; GO:0043281; GO:0045345; GO:0045751; GO:0050727; GO:0050728; GO:0070371; GO:0070373; GO:0071345; GO:1901223; GO:1901224 6795 XR_006393033.1 12 19 12 35 10 NA NA NA NA NA NA 6796 XM_029350815.2 1921 2744 1784 1568 1080 Q6GMK0 5.56e-179 Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B (EC 2.4.1.145) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVb) (GlcNAc-T IVb) (GnT-IVb) (N-acetylglucosaminyltransferase IVb) (UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVb) Danio rerio (Zebrafish) (Brachydanio rerio) protein glycosylation [GO:0006486]; protein N-linked glycosylation [GO:0006487] GO:0000139; GO:0005783; GO:0005793; GO:0005795; GO:0006486; GO:0006487; GO:0008375; GO:0008454; GO:0046872 6797 XM_029334725.2 1185 0 0 0 0 Q9C0E8 7.64e-67 Endoplasmic reticulum junction formation protein lunapark (ER junction formation factor lunapark) Homo sapiens (Human) blood coagulation [GO:0007596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum tubular network maintenance [GO:0071788]; endoplasmic reticulum tubular network organization [GO:0071786]; limb development [GO:0060173]; positive regulation of endoplasmic reticulum tubular network organization [GO:1903373]; regulation of chondrocyte differentiation [GO:0032330] GO:0005654; GO:0005783; GO:0005789; GO:0007029; GO:0007596; GO:0016020; GO:0032330; GO:0035115; GO:0042733; GO:0042802; GO:0046872; GO:0060173; GO:0071782; GO:0071786; GO:0071788; GO:0098826; GO:1903373 6798 XM_044310665.1 69 43 16 81 89 NA NA NA NA NA NA 6799 XM_029358345.2 814 427 357 837 692 NA NA NA NA NA NA 6800 XM_029330453.2 595 427 278 506 337 A2CI35 6.34e-38 Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein kinase) (Dusty PK) (Receptor-interacting serine/threonine-protein kinase 5) Strongylocentrotus purpuratus (Purple sea urchin) cellular response to fibroblast growth factor stimulus [GO:0044344]; embryonic organ development [GO:0048568]; negative regulation of apoptotic process [GO:0043066]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast growth factor receptor signaling pathway [GO:0045743] GO:0004674; GO:0004712; GO:0004713; GO:0005524; GO:0005737; GO:0016323; GO:0016324; GO:0043066; GO:0044344; GO:0045743; GO:0048568; GO:0070161; GO:0070374; GO:0106310 6801 XM_044315277.1 28 28 187 40 55 NA NA NA NA NA NA 6802 XM_029340490.2 263 203 151 291 419 NA NA NA NA NA NA 6803 XM_029344408.2 166 282 209 253 198 Q9UHC6 2.82e-35 Contactin-associated protein-like 2 (Cell recognition molecule Caspr2) Homo sapiens (Human) adult behavior [GO:0030534]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell population proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; clustering of voltage-gated potassium channels [GO:0045163]; learning [GO:0007612]; limbic system development [GO:0021761]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuron recognition [GO:0008038]; positive regulation of gap junction assembly [GO:1903598]; protein localization to juxtaparanode region of axon [GO:0071205]; social behavior [GO:0035176]; striatum development [GO:0021756]; superior temporal gyrus development [GO:0071109]; thalamus development [GO:0021794]; transmission of nerve impulse [GO:0019226]; vocal learning [GO:0042297]; vocalization behavior [GO:0071625] GO:0005769; GO:0005794; GO:0007155; GO:0007420; GO:0007612; GO:0008038; GO:0008076; GO:0008283; GO:0009986; GO:0016020; GO:0019226; GO:0019899; GO:0021756; GO:0021761; GO:0021794; GO:0021987; GO:0030424; GO:0030425; GO:0030534; GO:0030673; GO:0031175; GO:0033010; GO:0035176; GO:0042297; GO:0043025; GO:0043204; GO:0044224; GO:0045163; GO:0048812; GO:0071109; GO:0071205; GO:0071625; GO:1903598 6804 XM_029330250.2 820 690 324 877 590 Q6P2C0 1.1e-48 WD repeat-containing protein 93 Homo sapiens (Human) electron transport chain [GO:0022900] GO:0005747; GO:0022900 6805 XM_044313166.1 0 65 57 0 106 NA NA NA NA NA NA 6806 XM_029333229.2 0 0 22 0 0 Q16281 0 Cyclic nucleotide-gated cation channel alpha-3 (Cone photoreceptor cGMP-gated channel subunit alpha) (Cyclic nucleotide-gated channel alpha-3) (CNG channel alpha-3) (CNG-3) (CNG3) Homo sapiens (Human) cation transmembrane transport [GO:0098655]; cation transport [GO:0006812]; inorganic cation import across plasma membrane [GO:0098659]; response to cAMP [GO:0051591]; response to corticosteroid [GO:0031960]; response to magnesium ion [GO:0032026]; signal transduction [GO:0007165]; visual perception [GO:0007601] GO:0005222; GO:0005223; GO:0005737; GO:0005886; GO:0006812; GO:0007165; GO:0007601; GO:0008022; GO:0015276; GO:0017071; GO:0030425; GO:0030553; GO:0031960; GO:0032026; GO:0043194; GO:0043204; GO:0044877; GO:0051591; GO:0097386; GO:0098655; GO:0098659; GO:1902495 6807 XM_029349151.2 2 15 30 22 21 Q7ZWG6 5.69e-64 Proton-coupled folate transporter (Solute carrier family 46 member 1) Danio rerio (Zebrafish) (Brachydanio rerio) transmembrane transport [GO:0055085] GO:0005542; GO:0005768; GO:0005886; GO:0010008; GO:0015293; GO:0015350; GO:0016020; GO:0016323; GO:0016324; GO:0022857; GO:0055085 6808 XM_029332112.2 2 0 0 54 50 P56192 0 Methionine--tRNA ligase, cytoplasmic (EC 6.1.1.10) (Methionyl-tRNA synthetase) (MetRS) Homo sapiens (Human) cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; methionyl-tRNA aminoacylation [GO:0006431]; positive regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901838]; rRNA transcription [GO:0009303]; tRNA aminoacylation for protein translation [GO:0006418] GO:0000049; GO:0004825; GO:0005524; GO:0005730; GO:0005737; GO:0005829; GO:0006418; GO:0006431; GO:0009303; GO:0016020; GO:0017101; GO:0036120; GO:0070062; GO:0071364; GO:1901838 6809 XR_006392918.1 41 2 25 5 151 NA NA NA NA NA NA 6810 XM_044315035.1 0 0 24 0 14 NA NA NA NA NA NA 6811 XM_044329088.1 36 10 9 2 2 NA NA NA NA NA NA 6812 XM_029343311.2 249 72 120 162 294 Q8BFQ2 1.52e-29 Transmembrane protein 229B Mus musculus (Mouse) macrophage activation [GO:0042116]; response to bacterium [GO:0009617] GO:0009617; GO:0016020; GO:0042116 6813 XM_029349587.2 0 13 0 221 337 Q7ZVB2 0 4-trimethylaminobutyraldehyde dehydrogenase A (TMABA-DH) (TMABADH) (EC 1.2.1.47) (Aldehyde dehydrogenase family 9 member A1-A) (EC 1.2.1.3) Danio rerio (Zebrafish) (Brachydanio rerio) carnitine biosynthetic process [GO:0045329]; cellular aldehyde metabolic process [GO:0006081]; protein homotetramerization [GO:0051289] GO:0004029; GO:0005829; GO:0006081; GO:0019145; GO:0043878; GO:0045329; GO:0047105; GO:0051289 6814 XM_029345175.2 50 40 14 53 25 P31315 2.03e-21 GS homeobox 1 (Homeobox protein GSH-1) Mus musculus (Mouse) adenohypophysis development [GO:0021984]; central nervous system development [GO:0007417]; hypothalamus development [GO:0021854]; neuron differentiation [GO:0030182]; neuron fate commitment [GO:0048663]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; spinal cord association neuron differentiation [GO:0021527]; transcription by RNA polymerase II [GO:0006366] GO:0000978; GO:0000981; GO:0001228; GO:0005634; GO:0006357; GO:0006366; GO:0007417; GO:0021527; GO:0021854; GO:0021984; GO:0030182; GO:0043565; GO:0045944; GO:0048663; GO:1990837 6815 XR_006393524.1 129 16 57 4 18 NA NA NA NA NA NA 6816 XM_029345006.2 18 31 16 10 34 NA NA NA NA NA NA 6817 XM_029354273.2 2846 3152 1921 3599 2032 NA NA NA NA NA NA 6818 XM_044316288.1 0 0 0 0 7 NA NA NA NA NA NA 6819 XM_029332152.2 248 1074 115 180 269 NA NA NA NA NA NA 6820 XR_003822966.2 33 50 41 35 119 NA NA NA NA NA NA 6821 XR_003824894.2 262 250 96 178 226 NA NA NA NA NA NA 6822 XM_029343556.2 876 1074 507 1075 1112 P31266 0 Recombining binding protein suppressor of hairless (J kappa-recombination signal-binding protein) (RBP-J kappa) Mus musculus (Mouse) angiogenesis [GO:0001525]; aortic valve development [GO:0003176]; arterial endothelial cell fate commitment [GO:0060844]; artery morphogenesis [GO:0048844]; atrioventricular canal development [GO:0036302]; auditory receptor cell fate commitment [GO:0009912]; B cell differentiation [GO:0030183]; blood vessel endothelial cell fate specification [GO:0097101]; blood vessel lumenization [GO:0072554]; blood vessel remodeling [GO:0001974]; cardiac left ventricle morphogenesis [GO:0003214]; cardiac muscle cell myoblast differentiation [GO:0060379]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; cell population proliferation [GO:0008283]; club cell differentiation [GO:0060486]; defense response to bacterium [GO:0042742]; determination of heart left/right asymmetry [GO:0061371]; dorsal aorta morphogenesis [GO:0035912]; endocardium development [GO:0003157]; endocardium morphogenesis [GO:0003160]; epidermal cell fate specification [GO:0009957]; epithelial cell proliferation [GO:0050673]; epithelial to mesenchymal transition [GO:0001837]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; hair follicle maturation [GO:0048820]; heart development [GO:0007507]; heart looping [GO:0001947]; hemopoiesis [GO:0030097]; humoral immune response [GO:0006959]; inflammatory response to antigenic stimulus [GO:0002437]; keratinocyte differentiation [GO:0030216]; labyrinthine layer blood vessel development [GO:0060716]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of ossification [GO:0030279]; negative regulation of stem cell proliferation [GO:2000647]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron differentiation [GO:0030182]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; Notch signaling pathway involved in arterial endothelial cell fate commitment [GO:0060853]; outflow tract morphogenesis [GO:0003151]; pituitary gland development [GO:0021983]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment [GO:1901297]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell proliferation involved in heart morphogenesis [GO:2000138]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of ephrin receptor signaling pathway [GO:1901189]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERBB signaling pathway [GO:1901186]; positive regulation of gene expression [GO:0010628]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription of Notch receptor target [GO:0007221]; pulmonary valve development [GO:0003177]; regulation of cell adhesion involved in heart morphogenesis [GO:0061344]; regulation of epithelial cell proliferation [GO:0050678]; regulation of gene expression [GO:0010468]; regulation of reproductive process [GO:2000241]; regulation of timing of cell differentiation [GO:0048505]; regulation of transcription by RNA polymerase II [GO:0006357]; sebaceous gland development [GO:0048733]; secondary heart field specification [GO:0003139]; somatic stem cell population maintenance [GO:0035019]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222] GO:0000122; GO:0000978; GO:0000981; GO:0001228; GO:0001525; GO:0001756; GO:0001837; GO:0001947; GO:0001974; GO:0002193; GO:0002437; GO:0003139; GO:0003151; GO:0003157; GO:0003160; GO:0003176; GO:0003177; GO:0003198; GO:0003214; GO:0003222; GO:0003677; GO:0003682; GO:0005634; GO:0005654; GO:0005667; GO:0005730; GO:0005737; GO:0006357; GO:0006959; GO:0007219; GO:0007221; GO:0007507; GO:0008283; GO:0009912; GO:0009957; GO:0010468; GO:0010628; GO:0017053; GO:0021983; GO:0030097; GO:0030154; GO:0030182; GO:0030183; GO:0030216; GO:0030279; GO:0030513; GO:0032991; GO:0032993; GO:0035019; GO:0035481; GO:0035912; GO:0036302; GO:0042742; GO:0043011; GO:0043565; GO:0044877; GO:0045165; GO:0045596; GO:0045892; GO:0045893; GO:0045944; GO:0047485; GO:0048505; GO:0048733; GO:0048820; GO:0048844; GO:0050673; GO:0050678; GO:0050679; GO:0060045; GO:0060379; GO:0060412; GO:0060486; GO:0060716; GO:0060844; GO:0060853; GO:0061314; GO:0061344; GO:0061371; GO:0061419; GO:0061629; GO:0072089; GO:0072554; GO:0097101; GO:0120163; GO:0140297; GO:1901186; GO:1901189; GO:1901297; GO:2000138; GO:2000241; GO:2000647 6823 XM_044308265.1 32 0 0 4 29 NA NA NA NA NA NA 6824 XM_044315564.1 0 0 3 0 17 Q9H5F2 1.25e-25 Uncharacterized protein CFAP68 (cilia and flagella associated protein 68) Homo sapiens (Human) NA GO:0005654 6825 XR_003823711.2 0 32 0 0 0 NA NA NA NA NA NA 6826 XM_044323191.1 0 3 4 0 7 NA NA NA NA NA NA 6827 XM_029349161.2 1053 706 558 1164 989 Q91X43 6.89e-52 SH3 domain-containing protein 19 (Kryn) Mus musculus (Mouse) cytoskeleton organization [GO:0007010]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; regulation of cell morphogenesis [GO:0022604] GO:0005654; GO:0005829; GO:0005886; GO:0007010; GO:0022604; GO:0051044; GO:0070064 6828 XM_029349161.2 1053 706 558 1164 989 Q91X43 7.27e-50 SH3 domain-containing protein 19 (Kryn) Mus musculus (Mouse) cytoskeleton organization [GO:0007010]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; regulation of cell morphogenesis [GO:0022604] GO:0005654; GO:0005829; GO:0005886; GO:0007010; GO:0022604; GO:0051044; GO:0070064 6829 XM_044325397.1 0 7 0 6 18 Q91W90 1.1e-94 Thioredoxin domain-containing protein 5 (EC 1.8.4.-) (EC 5.3.4.1) (Endoplasmic reticulum resident protein 46) (ER protein 46) (ERp46) (Plasma cell-specific thioredoxin-related protein) (PC-TRP) (Thioredoxin-like protein p46) Mus musculus (Mouse) protein folding [GO:0006457] GO:0003756; GO:0005783; GO:0005788; GO:0006457; GO:0015035 6830 XM_044325397.1 0 7 0 6 18 Q91W90 4.55e-51 Thioredoxin domain-containing protein 5 (EC 1.8.4.-) (EC 5.3.4.1) (Endoplasmic reticulum resident protein 46) (ER protein 46) (ERp46) (Plasma cell-specific thioredoxin-related protein) (PC-TRP) (Thioredoxin-like protein p46) Mus musculus (Mouse) protein folding [GO:0006457] GO:0003756; GO:0005783; GO:0005788; GO:0006457; GO:0015035 6831 XM_044313811.1 8 1 16 0 8 NA NA NA NA NA NA 6832 XM_029349515.2 0 0 52 25 0 NA NA NA NA NA NA 6833 XM_029334949.2 1558 1042 974 1470 1357 Q28009 7.21e-26 RNA-binding protein FUS (Protein pigpen) Bos taurus (Bovine) regulation of DNA-templated transcription [GO:0006355] GO:0003677; GO:0003712; GO:0003723; GO:0005634; GO:0005737; GO:0006355; GO:0046872 6834 XR_003827428.2 368 61 317 121 1332 NA NA NA NA NA NA 6835 XM_044319538.1 16 0 0 0 0 Q96DM1 6.32e-23 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 6836 XM_044315860.1 416 144 398 320 426 B3EWZ6 0 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6837 XM_044315860.1 416 144 398 320 426 B3EWZ6 0 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6838 XM_044315860.1 416 144 398 320 426 B3EWZ6 0 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6839 XM_044315860.1 416 144 398 320 426 B3EWZ6 0 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6840 XM_044315860.1 416 144 398 320 426 B3EWZ6 0 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6841 XM_044315860.1 416 144 398 320 426 B3EWZ6 0 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6842 XM_044315860.1 416 144 398 320 426 B3EWZ6 0 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6843 XM_044315860.1 416 144 398 320 426 B3EWZ6 0 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6844 XM_044315860.1 416 144 398 320 426 B3EWZ6 0 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6845 XM_044315860.1 416 144 398 320 426 B3EWZ6 0 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6846 XM_044315860.1 416 144 398 320 426 B3EWZ6 0 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6847 XM_044315860.1 416 144 398 320 426 B3EWZ6 2.12e-95 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6848 XM_044315860.1 416 144 398 320 426 B3EWZ6 5.42e-80 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6849 XM_044315860.1 416 144 398 320 426 B3EWZ6 4.67e-53 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6850 XM_044314740.1 67 21 62 64 23 NA NA NA NA NA NA 6851 XR_006397889.1 42 74 53 62 160 NA NA NA NA NA NA 6852 XM_029341853.2 0 234 58 1225 695 NA NA NA NA NA NA 6853 XM_044315156.1 13 170 0 8 235 NA NA NA NA NA NA 6854 XM_029343542.2 2570 3233 1716 2220 1350 NA NA NA NA NA NA 6855 XM_029353546.2 0 0 0 1 11 NA NA NA NA NA NA 6856 XM_029331063.2 369 68 170 461 209 P07686 6.05e-174 Beta-hexosaminidase subunit beta (EC 3.2.1.52) (Beta-N-acetylhexosaminidase subunit beta) (Hexosaminidase subunit B) (Cervical cancer proto-oncogene 7 protein) (HCC-7) (N-acetyl-beta-glucosaminidase subunit beta) [Cleaved into: Beta-hexosaminidase subunit beta chain B; Beta-hexosaminidase subunit beta chain A] Homo sapiens (Human) astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; chondroitin sulfate catabolic process [GO:0030207]; dermatan sulfate catabolic process [GO:0030209]; ganglioside catabolic process [GO:0006689]; glycosaminoglycan metabolic process [GO:0030203]; hyaluronan catabolic process [GO:0030214]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; maintenance of location in cell [GO:0051651]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neuron cellular homeostasis [GO:0070050]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; single fertilization [GO:0007338]; skeletal system development [GO:0001501] GO:0001501; GO:0001669; GO:0004563; GO:0005576; GO:0005764; GO:0006689; GO:0006874; GO:0007040; GO:0007338; GO:0007341; GO:0007605; GO:0007626; GO:0008049; GO:0008360; GO:0008375; GO:0008654; GO:0009313; GO:0016020; GO:0019915; GO:0030203; GO:0030207; GO:0030209; GO:0030214; GO:0035578; GO:0042552; GO:0042582; GO:0042802; GO:0043202; GO:0043615; GO:0045944; GO:0048477; GO:0050885; GO:0051651; GO:0060473; GO:0070050; GO:0070062; GO:0102148; GO:1905379 6857 XM_044320221.1 610 326 36 97 113 NA NA NA NA NA NA 6858 XM_044314671.1 10 0 0 1 9 NA NA NA NA NA NA 6859 XM_029329075.2 381 341 350 273 190 P61315 7.55e-47 Galactose-3-O-sulfotransferase 3 (Gal3ST-3) (EC 2.8.2.-) (Beta-galactose-3-O-sulfotransferase 3) (Gal-beta-1, 3-GalNAc 3'-sulfotransferase 3) Mus musculus (Mouse) glycolipid biosynthetic process [GO:0009247] GO:0001733; GO:0008146; GO:0009247; GO:0032580; GO:0050694 6860 XM_029340822.2 5 0 0 0 27 P25102 6.32e-34 Histamine H2 receptor (H2R) (HH2R) (Gastric receptor I) Rattus norvegicus (Rat) cellular response to histamine [GO:0071420]; chemical synaptic transmission [GO:0007268]; digestive tract development [GO:0048565]; epithelial cell morphogenesis [GO:0003382]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; gastric acid secretion [GO:0001696]; gastrin-induced gastric acid secretion [GO:0001698]; gland development [GO:0048732]; histamine-induced gastric acid secretion [GO:0001697]; memory [GO:0007613]; negative regulation of arachidonic acid secretion [GO:1900139]; positive regulation of vasoconstriction [GO:0045907]; regulation of synaptic plasticity [GO:0048167]; toxin transport [GO:1901998]; visual learning [GO:0008542] GO:0001696; GO:0001697; GO:0001698; GO:0003382; GO:0004969; GO:0004993; GO:0005886; GO:0007187; GO:0007268; GO:0007613; GO:0008542; GO:0016020; GO:0030425; GO:0030594; GO:0045202; GO:0045907; GO:0048167; GO:0048565; GO:0048732; GO:0071420; GO:1900139; GO:1901363; GO:1901998 6861 XM_029331091.2 0 13 0 0 0 Q9CZX5 8.81e-45 PIN2/TERF1-interacting telomerase inhibitor 1 (67-11-3 protein) (LPTS1) (Liver-related putative tumor suppressor) (Pin2-interacting protein X1) (TRF1-interacting protein 1) Mus musculus (Mouse) mitotic metaphase plate congression [GO:0007080]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; positive regulation of protein localization to nucleolus [GO:1904751]; positive regulation of telomeric DNA binding [GO:1904744]; protein localization to chromosome, telomeric region [GO:0070198]; protein localization to nucleolus [GO:1902570]; regulation of protein stability [GO:0031647]; ribosomal small subunit biogenesis [GO:0042274]; telomere maintenance via telomerase [GO:0007004] GO:0000228; GO:0000776; GO:0000781; GO:0005654; GO:0005730; GO:0005739; GO:0005819; GO:0007004; GO:0007080; GO:0010521; GO:0010972; GO:0031397; GO:0031647; GO:0032211; GO:0042274; GO:0044877; GO:0051974; GO:0070034; GO:0070198; GO:1902570; GO:1904744; GO:1904751 6862 XM_029350114.2 0 0 185 115 0 NA NA NA NA NA NA 6863 XM_044318503.1 1831 1663 957 1849 2036 B2RYF1 4.87e-136 Protein phosphatase 1 regulatory subunit 37 (Leucine-rich repeat-containing protein 68) Rattus norvegicus (Rat) NA GO:0004864 6864 XR_006392011.1 0 0 6 0 0 NA NA NA NA NA NA 6865 XM_044320956.1 197 138 38 200 33 P52046 1.71e-28 Short-chain-enoyl-CoA hydratase (EC 4.2.1.150) (3-hydroxybutyryl-CoA dehydratase) (Crotonase) Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787) butyrate metabolic process [GO:0019605] GO:0016829; GO:0019605 6866 XM_029335792.2 40 95 21 210 50 NA NA NA NA NA NA 6867 XM_029356358.2 1465 814 789 1829 1540 Q8BW94 0 Dynein axonemal heavy chain 3 (Axonemal beta dynein heavy chain 3) (Ciliary dynein heavy chain 3) Mus musculus (Mouse) cilium movement [GO:0003341]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005524; GO:0005874; GO:0007018; GO:0008569; GO:0030286; GO:0036156; GO:0045505; GO:0051959; GO:0097729 6868 XM_029351928.2 422 326 142 335 408 NA NA NA NA NA NA 6869 XM_044320966.1 299 243 230 305 341 NA NA NA NA NA NA 6870 XM_029326453.2 80 68 89 0 0 Q9JI70 6.17e-72 Molecular chaperone MKKS (McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin) (Protein Bbs6 homolog) Mus musculus (Mouse) artery smooth muscle contraction [GO:0014824]; brain morphogenesis [GO:0048854]; cartilage development [GO:0051216]; cerebral cortex development [GO:0021987]; chaperone-mediated protein complex assembly [GO:0051131]; cilium assembly [GO:0060271]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; developmental process [GO:0032502]; face development [GO:0060324]; fat cell differentiation [GO:0045444]; gene expression [GO:0010467]; hippocampus development [GO:0021766]; intracellular transport [GO:0046907]; leptin-mediated signaling pathway [GO:0033210]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of appetite by leptin-mediated signaling pathway [GO:0038108]; negative regulation of blood pressure [GO:0045776]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of multicellular organism growth [GO:0040018]; protein folding [GO:0006457]; regulation of cilium beat frequency involved in ciliary motility [GO:0060296]; regulation of stress fiber assembly [GO:0051492]; response to leptin [GO:0044321]; sensory perception of smell [GO:0007608]; social behavior [GO:0035176]; spermatid development [GO:0007286]; striatum development [GO:0021756]; vasodilation [GO:0042311] GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0006457; GO:0007286; GO:0007608; GO:0010467; GO:0010629; GO:0014824; GO:0021756; GO:0021766; GO:0021987; GO:0030837; GO:0031514; GO:0032502; GO:0033210; GO:0034260; GO:0035176; GO:0036064; GO:0038108; GO:0040018; GO:0042311; GO:0044321; GO:0045444; GO:0045494; GO:0045776; GO:0046907; GO:0048854; GO:0050910; GO:0051082; GO:0051131; GO:0051216; GO:0051492; GO:0060271; GO:0060296; GO:0060324; GO:0061629; GO:1902636; GO:1905515 6871 XR_006391749.1 55 81 39 62 103 NA NA NA NA NA NA 6872 XM_029339127.2 27 32 13 40 48 B0UYT5 5.8e-56 Major facilitator superfamily domain-containing protein 6-B (Macrophage MHC class I receptor 2 homolog B) Danio rerio (Zebrafish) (Brachydanio rerio) antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590] GO:0005886; GO:0016020; GO:0042590 6873 XM_029345239.2 511 82 51 292 51 NA NA NA NA NA NA 6874 XM_044315339.1 0 46 8 37 52 NA NA NA NA NA NA 6875 XM_029332867.2 745 541 525 659 1001 NA NA NA NA NA NA 6876 XM_044311187.1 523 2091 823 1397 808 NA NA NA NA NA NA 6877 XM_044325760.1 3095 2973 2297 1666 1926 Q6CGG3 7.41e-36 FK506-binding protein 2 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica) chaperone-mediated protein folding [GO:0061077]; protein peptidyl-prolyl isomerization [GO:0000413] GO:0000413; GO:0003755; GO:0005783; GO:0061077 6878 XM_029324007.2 5815 8457 5766 10359 7196 P00129 3.32e-24 Cytochrome b-c1 complex subunit 7 (Complex III subunit 7) (Complex III subunit VII) (QP-C) (Ubiquinol-cytochrome c reductase complex 14 kDa protein) Bos taurus (Bovine) mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122] GO:0005750; GO:0006122 6879 XM_029352122.2 1541 828 447 202 77 Q5E9T4 2.42e-67 Thiamin pyrophosphokinase 1 (EC 2.7.6.2) (Thiamine pyrophosphokinase 1) Bos taurus (Bovine) phosphorylation [GO:0016310]; thiamine diphosphate biosynthetic process [GO:0009229]; thiamine metabolic process [GO:0006772] GO:0004788; GO:0005524; GO:0006772; GO:0009229; GO:0016301; GO:0016310; GO:0030975; GO:0042802 6880 XM_044321319.1 10 0 67 17 64 B3EWZ5 9.53e-23 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6881 XM_044321319.1 10 0 67 17 64 B3EWZ5 5.27e-22 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6882 XM_044321319.1 10 0 67 17 64 B3EWZ5 3.88e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6883 XM_044321319.1 10 0 67 17 64 B3EWZ5 6.73e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6884 XM_044321319.1 10 0 67 17 64 B3EWZ5 8.9e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6885 XM_044307033.1 424 186 896 661 943 B3EWY9 0 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 6886 XM_044307033.1 424 186 896 661 943 B3EWY9 2.56e-32 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 6887 XM_029357354.2 175 89 20 162 54 NA NA NA NA NA NA 6888 XM_029350728.2 30 0 40 0 47 NA NA NA NA NA NA 6889 XM_044314574.1 498 301 243 462 444 Q8N3S3 7.79e-108 Protein PHTF2 Homo sapiens (Human) NA GO:0005783; GO:0016020 6890 XM_044328949.1 0 0 0 11 41 NA NA NA NA NA NA 6891 XM_029344238.2 7 4 1 0 56 NA NA NA NA NA NA 6892 XR_006395423.1 0 0 0 116 0 Q9ULJ7 1.9e-46 Ankyrin repeat domain-containing protein 50 Homo sapiens (Human) endocytic recycling [GO:0032456]; protein transport [GO:0015031] GO:0005768; GO:0015031; GO:0032456 6893 XM_044320174.1 2 55 0 0 1 Q5DTN8 9.19e-50 Janus kinase and microtubule-interacting protein 3 (Neuroendocrine long coiled-coil protein 2) Mus musculus (Mouse) NA GO:0005794; GO:0008017; GO:0019900 6894 XM_044307038.1 0 5 2 9 1 NA NA NA NA NA NA 6895 XM_044321699.1 75 31 30 93 128 NA NA NA NA NA NA 6896 XR_006393876.1 72 0 8 7 64 NA NA NA NA NA NA 6897 XR_006392665.1 68 0 0 0 0 Q9NVH0 1.05e-27 Exonuclease 3'-5' domain-containing protein 2 (EC 3.1.11.1) (3'-5' exoribonuclease EXD2) (EC 3.1.13.-) (Exonuclease 3'-5' domain-like-containing protein 2) Homo sapiens (Human) DNA double-strand break processing [GO:0000729]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; replication fork processing [GO:0031297] GO:0000175; GO:0000287; GO:0000724; GO:0000729; GO:0003676; GO:0005634; GO:0005737; GO:0005739; GO:0005741; GO:0005759; GO:0006302; GO:0008296; GO:0008310; GO:0008408; GO:0008852; GO:0030145; GO:0031297; GO:0042803; GO:0045111; GO:0090305; GO:0090734 6898 XM_029338146.2 25 23 54 91 48 Q7ZVH1 7.98e-40 Membrane progestin receptor gamma-A (mPR gamma-A) (Progestin and adipoQ receptor family member V-A) Danio rerio (Zebrafish) (Brachydanio rerio) oogenesis [GO:0048477] GO:0005496; GO:0016020; GO:0038023; GO:0048477 6899 XM_044310235.1 21 0 1 19 10 NA NA NA NA NA NA 6900 XM_029357787.2 0 79 0 87 11 Q9EQD2 8.94e-46 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 6901 XR_006396802.1 4 260 2 56 0 NA NA NA NA NA NA 6902 XM_044311601.1 33 52 26 61 80 NA NA NA NA NA NA 6903 XR_006394923.1 97 137 26 106 5 NA NA NA NA NA NA 6904 XR_006397351.1 34 32 47 103 28 NA NA NA NA NA NA 6905 XM_029356015.2 23 14 31 19 40 D2H8V8 5.3e-104 5' exonuclease Apollo (EC 3.1.-.-) (Beta-lactamase MBLAC2) (EC 3.5.2.6) (DNA cross-link repair 1B protein) (SNM1 homolog B) Ailuropoda melanoleuca (Giant panda) DNA repair [GO:0006281]; protection from non-homologous end joining at telomere [GO:0031848]; telomere maintenance [GO:0000723]; telomeric 3' overhang formation [GO:0031860]; telomeric loop formation [GO:0031627] GO:0000723; GO:0000781; GO:0005634; GO:0005737; GO:0005813; GO:0006281; GO:0008409; GO:0008800; GO:0031627; GO:0031848; GO:0031860 6906 XM_044326371.1 25 5 7 1 102 Q8K4G1 1.47e-60 Latent-transforming growth factor beta-binding protein 4 (LTBP-4) Mus musculus (Mouse) elastic fiber assembly [GO:0048251]; hormone secretion [GO:0046879]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001527; GO:0005509; GO:0005576; GO:0007179; GO:0031012; GO:0046879; GO:0048251; GO:0050431; GO:0062023 6907 XM_044326371.1 25 5 7 1 102 Q8K4G1 1.28e-58 Latent-transforming growth factor beta-binding protein 4 (LTBP-4) Mus musculus (Mouse) elastic fiber assembly [GO:0048251]; hormone secretion [GO:0046879]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001527; GO:0005509; GO:0005576; GO:0007179; GO:0031012; GO:0046879; GO:0048251; GO:0050431; GO:0062023 6908 XM_044326371.1 25 5 7 1 102 Q8K4G1 2.83e-53 Latent-transforming growth factor beta-binding protein 4 (LTBP-4) Mus musculus (Mouse) elastic fiber assembly [GO:0048251]; hormone secretion [GO:0046879]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001527; GO:0005509; GO:0005576; GO:0007179; GO:0031012; GO:0046879; GO:0048251; GO:0050431; GO:0062023 6909 XM_044326371.1 25 5 7 1 102 Q8K4G1 2.35e-43 Latent-transforming growth factor beta-binding protein 4 (LTBP-4) Mus musculus (Mouse) elastic fiber assembly [GO:0048251]; hormone secretion [GO:0046879]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001527; GO:0005509; GO:0005576; GO:0007179; GO:0031012; GO:0046879; GO:0048251; GO:0050431; GO:0062023 6910 XM_044326371.1 25 5 7 1 102 Q8K4G1 8.01e-39 Latent-transforming growth factor beta-binding protein 4 (LTBP-4) Mus musculus (Mouse) elastic fiber assembly [GO:0048251]; hormone secretion [GO:0046879]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001527; GO:0005509; GO:0005576; GO:0007179; GO:0031012; GO:0046879; GO:0048251; GO:0050431; GO:0062023 6911 XM_044326371.1 25 5 7 1 102 Q8K4G1 4.36e-31 Latent-transforming growth factor beta-binding protein 4 (LTBP-4) Mus musculus (Mouse) elastic fiber assembly [GO:0048251]; hormone secretion [GO:0046879]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001527; GO:0005509; GO:0005576; GO:0007179; GO:0031012; GO:0046879; GO:0048251; GO:0050431; GO:0062023 6912 XM_044326371.1 25 5 7 1 102 Q8K4G1 3.51e-23 Latent-transforming growth factor beta-binding protein 4 (LTBP-4) Mus musculus (Mouse) elastic fiber assembly [GO:0048251]; hormone secretion [GO:0046879]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001527; GO:0005509; GO:0005576; GO:0007179; GO:0031012; GO:0046879; GO:0048251; GO:0050431; GO:0062023 6913 XM_029350866.2 0 114 247 13 0 Q6VFT6 1.29e-53 Forkhead box protein L2 Sus scrofa (Pig) anatomical structure morphogenesis [GO:0009653]; apoptotic DNA fragmentation [GO:0006309]; cell differentiation [GO:0030154]; embryonic eye morphogenesis [GO:0048048]; extraocular skeletal muscle development [GO:0002074]; female somatic sex determination [GO:0019101]; granulosa cell differentiation [GO:0060014]; ovarian follicle development [GO:0001541]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0001541; GO:0002074; GO:0003677; GO:0003700; GO:0005634; GO:0006309; GO:0006357; GO:0009653; GO:0019101; GO:0030154; GO:0043028; GO:0043065; GO:0043280; GO:0045893; GO:0045944; GO:0048048; GO:0060014 6914 XM_029355006.2 742 629 271 515 436 A7SPX9 4.73e-132 Eukaryotic translation initiation factor 3 subunit M (eIF3m) Nematostella vectensis (Starlet sea anemone) cytoplasmic translational initiation [GO:0002183]; formation of cytoplasmic translation initiation complex [GO:0001732] GO:0001732; GO:0002183; GO:0003743; GO:0005852; GO:0016282; GO:0033290; GO:0071541 6915 XM_029351348.2 0 0 0 45 0 Q9PUU6 1.57e-33 Frizzled-2 (Fz-2) (Xfz2) Xenopus laevis (African clawed frog) Wnt signaling pathway [GO:0016055] GO:0004930; GO:0005886; GO:0016055 6916 XM_029351348.2 0 0 0 45 0 Q9PUU6 2.54e-22 Frizzled-2 (Fz-2) (Xfz2) Xenopus laevis (African clawed frog) Wnt signaling pathway [GO:0016055] GO:0004930; GO:0005886; GO:0016055 6917 XM_044319008.1 372 478 388 486 707 A7SEP9 2.07e-33 U1 small nuclear ribonucleoprotein C (U1 snRNP C) (U1-C) (U1C) Nematostella vectensis (Starlet sea anemone) mRNA 5'-splice site recognition [GO:0000395]; spliceosomal snRNP assembly [GO:0000387] GO:0000243; GO:0000387; GO:0000395; GO:0003729; GO:0005685; GO:0008270; GO:0030619; GO:0030627; GO:0071004 6918 XM_029331199.2 42 30 24 44 42 NA NA NA NA NA NA 6919 XR_006391521.1 0 0 2 1 12 NA NA NA NA NA NA 6920 XR_006391611.1 125 19 108 141 116 NA NA NA NA NA NA 6921 XM_044315814.1 5 1 0 0 7 Q2TL32 8.04e-31 E3 ubiquitin-protein ligase UBR4 (EC 2.3.2.27) (N-recognin-4) (RING-type E3 ubiquitin transferase UBR4) (Zinc finger UBR1-type protein 1) Rattus norvegicus (Rat) ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004842; GO:0005516; GO:0005654; GO:0005813; GO:0005829; GO:0006511; GO:0008270; GO:0016020; GO:0061630 6922 XM_029326861.2 11 7 0 6 1 R1CW23 3.05e-83 Dimethylsulfonioproprionate lyase 7 (DMSP lyase 7) (EC 4.4.1.3) (Dimethylpropiothetin dethiomethylase 7) Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi) NA GO:0047869 6923 XM_044316209.1 897 845 359 668 286 NA NA NA NA NA NA 6924 XM_044327134.1 0 0 42 0 3 NA NA NA NA NA NA 6925 XM_044322970.1 12 7 30 34 27 NA NA NA NA NA NA 6926 XM_029336726.2 1081 1013 700 1316 1176 NA NA NA NA NA NA 6927 XM_044321738.1 279 0 209 284 0 NA NA NA NA NA NA 6928 XM_044310775.1 47 33 0 55 47 NA NA NA NA NA NA 6929 XR_006394551.1 106 39 55 89 155 NA NA NA NA NA NA 6930 XM_044318192.1 18 0 13 10 0 NA NA NA NA NA NA 6931 XM_029356235.2 1799 1211 846 1373 955 P11980 0 Pyruvate kinase PKM (EC 2.7.1.40) (Pyruvate kinase muscle isozyme) (Threonine-protein kinase PKM2) (EC 2.7.11.1) (Tyrosine-protein kinase PKM2) (EC 2.7.10.2) Rattus norvegicus (Rat) animal organ regeneration [GO:0031100]; ATP biosynthetic process [GO:0006754]; canonical glycolysis [GO:0061621]; cellular response to insulin stimulus [GO:0032869]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]; liver development [GO:0001889]; positive regulation of cytoplasmic translation [GO:2000767]; positive regulation of sprouting angiogenesis [GO:1903672]; programmed cell death [GO:0012501]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; pyruvate biosynthetic process [GO:0042866]; pyruvate metabolic process [GO:0006090]; response to gravity [GO:0009629]; response to hypoxia [GO:0001666]; response to insulin [GO:0032868]; response to muscle inactivity [GO:0014870]; response to nutrient [GO:0007584]; response to organic substance [GO:0010033]; skeletal muscle tissue regeneration [GO:0043403] GO:0000287; GO:0001666; GO:0001889; GO:0003729; GO:0004713; GO:0004743; GO:0005524; GO:0005634; GO:0005737; GO:0005791; GO:0005829; GO:0005929; GO:0006006; GO:0006090; GO:0006096; GO:0006754; GO:0007584; GO:0009629; GO:0010033; GO:0012501; GO:0014870; GO:0030955; GO:0031100; GO:0032868; GO:0032869; GO:0042802; GO:0042866; GO:0043403; GO:0043531; GO:0046983; GO:0051262; GO:0051289; GO:0061621; GO:0070324; GO:1902912; GO:1903672; GO:2000767 6932 XM_029343457.2 0 0 0 96 88 NA NA NA NA NA NA 6933 XM_044318032.1 58 0 54 10 301 NA NA NA NA NA NA 6934 XR_006397662.1 1944 1593 1040 1686 1099 NA NA NA NA NA NA 6935 XM_044324040.1 9 8 2 6 11 P09884 0 DNA polymerase alpha catalytic subunit (EC 2.7.7.7) (DNA polymerase alpha catalytic subunit p180) Homo sapiens (Human) DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication initiation [GO:0006270]; DNA replication, synthesis of RNA primer [GO:0006269]; DNA strand elongation involved in DNA replication [GO:0006271]; DNA synthesis involved in DNA repair [GO:0000731]; double-strand break repair via nonhomologous end joining [GO:0006303]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; mitotic DNA replication initiation [GO:1902975]; regulation of type I interferon production [GO:0032479] GO:0000166; GO:0000731; GO:0003677; GO:0003682; GO:0003688; GO:0003697; GO:0003887; GO:0005634; GO:0005635; GO:0005654; GO:0005658; GO:0005730; GO:0005829; GO:0006260; GO:0006269; GO:0006270; GO:0006271; GO:0006272; GO:0006273; GO:0006281; GO:0006303; GO:0008270; GO:0016363; GO:0019901; GO:0032479; GO:1902975 6936 XM_044325077.1 23 1 17 3 54 P15043 1.46e-30 ATP-dependent DNA helicase RecQ (EC 3.6.4.12) Escherichia coli (strain K12) cellular response to DNA damage stimulus [GO:0006974]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; SOS response [GO:0009432] GO:0003677; GO:0003678; GO:0005524; GO:0005694; GO:0005737; GO:0006260; GO:0006281; GO:0006310; GO:0006974; GO:0008094; GO:0008270; GO:0009378; GO:0009432; GO:0016887; GO:0017116; GO:0017117; GO:0030894; GO:0032508; GO:0043138; GO:0043590; GO:0046914 6937 XM_044307177.1 35 56 30 33 45 NA NA NA NA NA NA 6938 XR_006394758.1 106 130 74 195 149 NA NA NA NA NA NA 6939 XM_044311237.1 0 5 51 3 147 P46023 7.36e-84 G-protein coupled receptor GRL101 Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004930; GO:0005886 6940 XM_044319316.1 22 0 0 20 11 Q8WPA2 6.1e-29 Allatostatin-A receptor (BAR) Bombyx mori (Silk moth) NA GO:0004930; GO:0005886; GO:0042562; GO:0042923 6941 XM_044329165.1 0 287 112 451 192 NA NA NA NA NA NA 6942 XM_029353049.2 12 0 0 0 0 Q7ZX59 8.34e-52 Cytokine receptor-like factor 3 Xenopus laevis (African clawed frog) NA GO:0005737 6943 XR_006394850.1 1204 254 766 820 585 Q9WU01 9.85e-64 KH domain-containing, RNA-binding, signal transduction-associated protein 2 (Sam68-like mammalian protein 1) (SLM-1) (mSLM-1) Mus musculus (Mouse) mRNA processing [GO:0006397]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of mRNA splicing, via spliceosome [GO:0048024] GO:0000381; GO:0003729; GO:0005634; GO:0006397; GO:0008143; GO:0008266; GO:0017124; GO:0042169; GO:0048024 6944 XM_029353095.2 0 0 20 0 111 Q63ZI0 2.14e-80 Potassium channel subfamily K member 9 Xenopus laevis (African clawed frog) NA GO:0005267; GO:0005886 6945 XM_044319769.1 0 6 0 0 0 Q6NYL5 6.79e-138 Alanine aminotransferase 2-like (ALT2) (EC 2.6.1.2) (Glutamate pyruvate transaminase 2) (GPT 2) (Glutamic--alanine transaminase 2) (Glutamic--pyruvic transaminase 2) Danio rerio (Zebrafish) (Brachydanio rerio) 2-oxoglutarate metabolic process [GO:0006103]; biosynthetic process [GO:0009058]; L-alanine catabolic process [GO:0042853]; L-alanine metabolic process [GO:0042851] GO:0004021; GO:0006103; GO:0009058; GO:0030170; GO:0042851; GO:0042853 6946 XM_029351806.2 151 67 80 86 122 Q24K12 2.23e-142 G patch domain-containing protein 1 Bos taurus (Bovine) mRNA processing [GO:0006397] GO:0003676; GO:0006397 6947 XR_006393443.1 258 128 181 98 113 NA NA NA NA NA NA 6948 XM_044317134.1 235 236 26 78 315 Q9DB41 1.42e-97 Mitochondrial glutamate carrier 2 (GC-2) (Glutamate/H(+) symporter 2) (Solute carrier family 25 member 18) Mus musculus (Mouse) aspartate transmembrane transport [GO:0015810]; L-glutamate transmembrane transport [GO:0015813]; malate-aspartate shuttle [GO:0043490] GO:0005280; GO:0005313; GO:0005743; GO:0015183; GO:0015810; GO:0015813; GO:0022857; GO:0043490 6949 XM_044325970.1 9 1 4 5 55 NA NA NA NA NA NA 6950 XR_006391996.1 39 1 32 67 80 NA NA NA NA NA NA 6951 XR_006396253.1 0 220 154 0 254 NA NA NA NA NA NA 6952 XM_044313260.1 0 0 10 336 0 A2AP18 0 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-eta-2) (Phosphoinositide phospholipase C-like 4) (PLC-L4) (Phospholipase C-like protein 4) (Phospholipase C-eta-2) (PLC-eta2) Mus musculus (Mouse) lipid catabolic process [GO:0016042]; phosphatidylinositol metabolic process [GO:0046488]; phosphatidylinositol-mediated signaling [GO:0048015] GO:0004435; GO:0004629; GO:0005509; GO:0005737; GO:0005886; GO:0016042; GO:0046488; GO:0048015 6953 XR_006397728.1 83 120 56 68 80 NA NA NA NA NA NA 6954 XM_044313339.1 3 0 5 0 11 NA NA NA NA NA NA 6955 XM_044317932.1 37 0 44 28 32 NA NA NA NA NA NA 6956 XM_044320187.1 0 0 0 1 275 E9Q236 0 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 6957 XM_029332063.2 0 37 0 71 111 NA NA NA NA NA NA 6958 XM_044324649.1 26 19 10 16 34 NA NA NA NA NA NA 6959 XM_029349783.2 28 23 0 326 249 NA NA NA NA NA NA 6960 XM_044313570.1 714 519 459 812 812 Q8AVY1 1.19e-73 Outer dense fiber protein 3 (Outer dense fiber of sperm tails protein 3) Xenopus laevis (African clawed frog) NA GO:0005737 6961 XR_006391437.1 89 1 2 2 57 NA NA NA NA NA NA 6962 XM_029324738.2 124 83 0 0 170 Q68F72 1.42e-92 Solute carrier family 15 member 4 Xenopus laevis (African clawed frog) dipeptide import across plasma membrane [GO:0140206]; innate immune response [GO:0045087]; mast cell homeostasis [GO:0033023]; peptidoglycan transport [GO:0015835]; positive regulation of innate immune response [GO:0045089]; positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [GO:0070430]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of toll-like receptor 7 signaling pathway [GO:0034157]; positive regulation of toll-like receptor 8 signaling pathway [GO:0034161]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; protein transport [GO:0015031]; regulation of isotype switching to IgG isotypes [GO:0048302]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424] GO:0005290; GO:0005765; GO:0015031; GO:0015333; GO:0015647; GO:0015835; GO:0031901; GO:0033023; GO:0034157; GO:0034161; GO:0034165; GO:0036020; GO:0045087; GO:0045089; GO:0048302; GO:0070424; GO:0070430; GO:0070434; GO:0071916; GO:0140206 6963 XR_006393204.1 36 0 24 11 0 NA NA NA NA NA NA 6964 XM_044317167.1 1225 635 529 919 1370 Q5R7R6 0 Conserved oligomeric Golgi complex subunit 4 (COG complex subunit 4) (Component of oligomeric Golgi complex 4) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) protein transport [GO:0015031] GO:0000139; GO:0005829; GO:0015031 6965 XM_029358218.2 221 1337 116 293 216 NA NA NA NA NA NA 6966 XM_029355497.2 13 13 24 24 39 NA NA NA NA NA NA 6967 XM_029336752.2 19798 22686 13169 22287 5448 NA NA NA NA NA NA 6968 XM_044321075.1 3 0 0 10 0 C3ZQF9 3.2e-23 QRFP-like peptide receptor Branchiostoma floridae (Florida lancelet) (Amphioxus) cellular response to peptide [GO:1901653]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:1901653 6969 XM_044310970.1 249 67 196 155 736 NA NA NA NA NA NA 6970 XM_029340654.2 112 77 44 28 38 NA NA NA NA NA NA 6971 XM_044311462.1 74 0 46 0 0 Q3SZN3 1.28e-39 Metalloendopeptidase OMA1, mitochondrial (EC 3.4.24.-) (Overlapping with the m-AAA protease 1 homolog) Bos taurus (Bovine) diet induced thermogenesis [GO:0002024]; energy homeostasis [GO:0097009]; glucose metabolic process [GO:0006006]; HRI-mediated signaling [GO:0140468]; integrated stress response signaling [GO:0140467]; lipid metabolic process [GO:0006629]; mitochondrial protein processing [GO:0034982]; mitochondrial respiratory chain complex assembly [GO:0033108]; negative regulation of mitochondrial fusion [GO:0010637]; positive regulation of apoptotic process [GO:0043065]; protein autoprocessing [GO:0016540]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of cristae formation [GO:1903850]; zymogen activation [GO:0031638] GO:0002024; GO:0004222; GO:0005743; GO:0006006; GO:0006515; GO:0006629; GO:0008289; GO:0010637; GO:0016020; GO:0016540; GO:0031638; GO:0031966; GO:0033108; GO:0034982; GO:0043065; GO:0046872; GO:0051603; GO:0097009; GO:0140467; GO:0140468; GO:1903850 6972 XM_044311462.1 74 0 46 0 0 Q3SZN3 1.28e-39 Metalloendopeptidase OMA1, mitochondrial (EC 3.4.24.-) (Overlapping with the m-AAA protease 1 homolog) Bos taurus (Bovine) diet induced thermogenesis [GO:0002024]; energy homeostasis [GO:0097009]; glucose metabolic process [GO:0006006]; HRI-mediated signaling [GO:0140468]; integrated stress response signaling [GO:0140467]; lipid metabolic process [GO:0006629]; mitochondrial protein processing [GO:0034982]; mitochondrial respiratory chain complex assembly [GO:0033108]; negative regulation of mitochondrial fusion [GO:0010637]; positive regulation of apoptotic process [GO:0043065]; protein autoprocessing [GO:0016540]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of cristae formation [GO:1903850]; zymogen activation [GO:0031638] GO:0002024; GO:0004222; GO:0005743; GO:0006006; GO:0006515; GO:0006629; GO:0008289; GO:0010637; GO:0016020; GO:0016540; GO:0031638; GO:0031966; GO:0033108; GO:0034982; GO:0043065; GO:0046872; GO:0051603; GO:0097009; GO:0140467; GO:0140468; GO:1903850 6973 XM_029350901.2 119 100 57 258 95 NA NA NA NA NA NA 6974 XM_044315430.1 7 273 57 52 145 Q7RTR2 7.2e-58 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 6975 XM_044315430.1 7 273 57 52 145 Q7RTR2 1.04e-57 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 6976 XM_044315430.1 7 273 57 52 145 Q7RTR2 1.38e-44 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 6977 XM_044315430.1 7 273 57 52 145 Q7RTR2 1.38e-24 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 6978 XM_044315430.1 7 273 57 52 145 Q7RTR2 1.38e-24 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 6979 XM_029345795.2 7328 7419 4622 3677 5704 Q9D1M0 5.34e-153 Protein SEC13 homolog (GATOR complex protein SEC13) (SEC13-like protein 1) (SEC13-related protein) Mus musculus (Mouse) COPII-coated vesicle budding [GO:0090114]; COPII-coated vesicle cargo loading [GO:0090110]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; mRNA transport [GO:0051028]; nucleocytoplasmic transport [GO:0006913]; positive regulation of TOR signaling [GO:0032008]; protein exit from endoplasmic reticulum [GO:0032527]; protein import into nucleus [GO:0006606]; protein localization to plasma membrane [GO:0072659] GO:0000776; GO:0005198; GO:0005635; GO:0005643; GO:0005654; GO:0005765; GO:0005783; GO:0005789; GO:0005829; GO:0006606; GO:0006888; GO:0006913; GO:0030127; GO:0031080; GO:0032008; GO:0032527; GO:0032991; GO:0042802; GO:0043231; GO:0051028; GO:0061700; GO:0072659; GO:0090110; GO:0090114 6980 XM_029349288.2 1544 938 684 1080 1038 Q5XIP9 1.6e-94 Transmembrane protein 43 (Protein LUMA) Rattus norvegicus (Rat) innate immune response [GO:0045087]; nuclear membrane organization [GO:0071763] GO:0005637; GO:0005788; GO:0005789; GO:0005886; GO:0042802; GO:0043621; GO:0045087; GO:0071763 6981 XM_044320002.1 223 75 144 178 331 Q6DDI6 0 TBC1 domain family member 31 Xenopus laevis (African clawed frog) cilium assembly [GO:0060271] GO:0005737; GO:0005813; GO:0034451; GO:0036064; GO:0060090; GO:0060271 6982 XM_029334778.2 2838 2141 2716 3011 2776 Q16611 2.17e-35 Bcl-2 homologous antagonist/killer (Apoptosis regulator BAK) (Bcl-2-like protein 7) (Bcl2-L-7) Homo sapiens (Human) activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; aging [GO:0007568]; animal organ regeneration [GO:0031100]; apoptotic process [GO:0006915]; apoptotic process involved in blood vessel morphogenesis [GO:1902262]; apoptotic signaling pathway [GO:0097190]; B cell apoptotic process [GO:0001783]; B cell homeostasis [GO:0001782]; B cell negative selection [GO:0002352]; blood vessel remodeling [GO:0001974]; brain development [GO:0007420]; calcium ion transport into cytosol [GO:0060402]; cellular response to mechanical stimulus [GO:0071260]; cellular response to unfolded protein [GO:0034620]; cellular response to UV [GO:0034644]; endocrine pancreas development [GO:0031018]; endoplasmic reticulum calcium ion homeostasis [GO:0032469]; epithelial cell proliferation [GO:0050673]; establishment or maintenance of transmembrane electrochemical gradient [GO:0010248]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fibroblast apoptotic process [GO:0044346]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; limb morphogenesis [GO:0035108]; mitochondrial fusion [GO:0008053]; myeloid cell homeostasis [GO:0002262]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; negative regulation of gene expression [GO:0010629]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of apoptotic process [GO:0043065]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901030]; positive regulation of protein-containing complex assembly [GO:0031334]; positive regulation of proteolysis [GO:0045862]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; post-embryonic camera-type eye morphogenesis [GO:0048597]; regulation of cell cycle [GO:0051726]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane potential [GO:0051881]; release of cytochrome c from mitochondria [GO:0001836]; response to ethanol [GO:0045471]; response to fungus [GO:0009620]; response to gamma radiation [GO:0010332]; response to hydrogen peroxide [GO:0042542]; response to mycotoxin [GO:0010046]; response to organic cyclic compound [GO:0014070]; response to UV-C [GO:0010225]; response to xenobiotic stimulus [GO:0009410]; thymocyte apoptotic process [GO:0070242]; vagina development [GO:0060068] GO:0001782; GO:0001783; GO:0001836; GO:0001974; GO:0002262; GO:0002352; GO:0005739; GO:0005741; GO:0005783; GO:0005829; GO:0006915; GO:0007420; GO:0007568; GO:0008053; GO:0008285; GO:0008630; GO:0008635; GO:0009410; GO:0009620; GO:0010046; GO:0010225; GO:0010248; GO:0010332; GO:0010524; GO:0010629; GO:0014070; GO:0018105; GO:0031018; GO:0031072; GO:0031100; GO:0031334; GO:0032469; GO:0032471; GO:0033137; GO:0034620; GO:0034644; GO:0035108; GO:0042542; GO:0042802; GO:0042803; GO:0043065; GO:0044325; GO:0044346; GO:0044877; GO:0045471; GO:0045862; GO:0046872; GO:0046902; GO:0046930; GO:0046982; GO:0048597; GO:0050673; GO:0051087; GO:0051400; GO:0051726; GO:0051881; GO:0060068; GO:0060402; GO:0070059; GO:0070242; GO:0071260; GO:0090200; GO:0090201; GO:0097136; GO:0097145; GO:0097190; GO:0097192; GO:0097202; GO:1900103; GO:1901029; GO:1901030; GO:1902262; GO:1903896 6983 XR_006394261.1 11 4 43 9 189 NA NA NA NA NA NA 6984 XR_006391672.1 16 5 0 16 49 NA NA NA NA NA NA 6985 XM_044317463.1 453 26 12 22 25 Q5SWK7 1.36e-43 RING finger protein 145 (EC 2.3.2.27) Mus musculus (Mouse) NA GO:0005783; GO:0005789; GO:0008270; GO:0012505; GO:0061630 6986 XR_006394028.1 46 16 0 4 14 NA NA NA NA NA NA 6987 XM_044328732.1 0 0 0 0 20 NA NA NA NA NA NA 6988 XM_029339472.2 1281 1276 719 990 1215 O60381 1.82e-37 HMG box-containing protein 1 (HMG box transcription factor 1) (High mobility group box transcription factor 1) Homo sapiens (Human) regulation of cell cycle [GO:0051726]; regulation of transcription by RNA polymerase II [GO:0006357]; Wnt signaling pathway [GO:0016055] GO:0000785; GO:0000978; GO:0000981; GO:0003723; GO:0005634; GO:0005654; GO:0006357; GO:0016055; GO:0016607; GO:0051726 6989 XM_029356741.2 1799 1673 1323 1624 1729 NA NA NA NA NA NA 6990 XM_029355996.2 771 684 511 861 1101 NA NA NA NA NA NA 6991 XM_044313383.1 12 5 3 0 52 NA NA NA NA NA NA 6992 XM_044317013.1 274 79 106 82 75 Q9N126 1.87e-53 Retinol dehydrogenase 8 (EC 1.1.1.300) (Photoreceptor outer segment all-trans retinol dehydrogenase) Bos taurus (Bovine) estrogen biosynthetic process [GO:0006703]; response to stimulus [GO:0050896]; retinol metabolic process [GO:0042572]; visual perception [GO:0007601] GO:0004303; GO:0004745; GO:0005829; GO:0006703; GO:0007601; GO:0016491; GO:0042572; GO:0042622; GO:0050896; GO:0052650 6993 XM_029343036.2 0 22 38 46 19 NA NA NA NA NA NA 6994 XM_029348054.2 841 628 367 904 583 A7SFB5 3.09e-29 Cyclic GMP-AMP synthase (NvcGAS) (cGAMP synthase) (cGAS) (nv-cGAS) (EC 2.7.7.86) (3'3'-cGAMP synthase) Nematostella vectensis (Starlet sea anemone) NA GO:0005524; GO:0005525; GO:0005829; GO:0046872; GO:0061501 6995 XM_029347602.2 277 246 139 419 335 NA NA NA NA NA NA 6996 XM_044318274.1 0 0 34 0 16 NA NA NA NA NA NA 6997 XM_044329123.1 0 0 0 53 0 NA NA NA NA NA NA 6998 XM_029353370.2 3 3 12 0 30 Q91175 1.37e-49 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (MAR1) Oryzias latipes (Japanese rice fish) (Japanese killifish) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of vasoconstriction [GO:0045907] GO:0001996; GO:0004930; GO:0004937; GO:0005886; GO:0007200; GO:0007204; GO:0007267; GO:0043410; GO:0045907; GO:0071880 6999 XM_044325447.1 901 513 623 811 1144 Q867C9 0 ATP-dependent 6-phosphofructokinase, muscle type (ATP-PFK) (PFK-M) (EC 2.7.1.11) (6-phosphofructokinase type A) (Phosphofructo-1-kinase isozyme A) (PFK-A) (Phosphohexokinase) Equus caballus (Horse) canonical glycolysis [GO:0061621]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose 6-phosphate metabolic process [GO:0006002] GO:0003872; GO:0005524; GO:0005945; GO:0006002; GO:0016020; GO:0016208; GO:0030388; GO:0042802; GO:0046872; GO:0048029; GO:0061621; GO:0070095 7000 XM_044317486.1 392 578 819 0 409 Q13114 2.03e-99 TNF receptor-associated factor 3 (EC 2.3.2.27) (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein 1) (LAP1) (RING-type E3 ubiquitin transferase TRAF3) Homo sapiens (Human) apoptotic process [GO:0006915]; defense response to virus [GO:0051607]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of JNK cascade [GO:0046330]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of cytokine production [GO:0001817]; regulation of defense response to virus [GO:0050688]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of interferon-beta production [GO:0032648]; regulation of proteolysis [GO:0030162]; signal transduction [GO:0007165]; Toll signaling pathway [GO:0008063]; toll-like receptor signaling pathway [GO:0002224]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; type I interferon-mediated signaling pathway [GO:0060337] GO:0000151; GO:0001817; GO:0002224; GO:0004842; GO:0005164; GO:0005739; GO:0005768; GO:0005829; GO:0006915; GO:0007165; GO:0008063; GO:0008270; GO:0009898; GO:0019901; GO:0019903; GO:0030162; GO:0031625; GO:0031996; GO:0032088; GO:0032648; GO:0033209; GO:0035631; GO:0035666; GO:0042802; GO:0042981; GO:0043122; GO:0046330; GO:0050688; GO:0051607; GO:0060337; GO:0070534; GO:1902554 7001 XM_029344640.2 6 10 17 2 9 Q9UL51 2.08e-132 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) Homo sapiens (Human) cell-cell signaling [GO:0007267]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; membrane depolarization during cardiac muscle cell action potential [GO:0086012]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; regulation of cation channel activity [GO:2001257]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of membrane depolarization [GO:0003254]; regulation of membrane potential [GO:0042391]; regulation of SA node cell action potential [GO:0098907]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725] GO:0003254; GO:0005222; GO:0005248; GO:0005249; GO:0005886; GO:0007267; GO:0008076; GO:0030424; GO:0030425; GO:0030552; GO:0035725; GO:0042391; GO:0042802; GO:0071320; GO:0071321; GO:0071805; GO:0086012; GO:0086091; GO:0098719; GO:0098855; GO:0098907; GO:1990573; GO:2001257 7002 XR_006396991.1 0 22 0 323 0 NA NA NA NA NA NA 7003 XM_044311353.1 3 0 0 14 0 Q95LR0 7.99e-52 Cilia- and flagella-associated protein 91 (CFAP91) (AMY-1-associating protein expressed in testis 1) (AAT-1) (MYCBP/AMY-1-associated testis-expressed protein 1) (Protein MAATS1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) axonemal central apparatus assembly [GO:1904158]; cell differentiation [GO:0030154]; cilium movement [GO:0003341]; spermatogenesis [GO:0007283] GO:0003341; GO:0005739; GO:0005930; GO:0007283; GO:0030154; GO:0031514; GO:1904158 7004 XM_044311353.1 3 0 0 14 0 Q95LR0 7.99e-52 Cilia- and flagella-associated protein 91 (CFAP91) (AMY-1-associating protein expressed in testis 1) (AAT-1) (MYCBP/AMY-1-associated testis-expressed protein 1) (Protein MAATS1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) axonemal central apparatus assembly [GO:1904158]; cell differentiation [GO:0030154]; cilium movement [GO:0003341]; spermatogenesis [GO:0007283] GO:0003341; GO:0005739; GO:0005930; GO:0007283; GO:0030154; GO:0031514; GO:1904158 7005 XM_044311353.1 3 0 0 14 0 Q95LR0 7.99e-52 Cilia- and flagella-associated protein 91 (CFAP91) (AMY-1-associating protein expressed in testis 1) (AAT-1) (MYCBP/AMY-1-associated testis-expressed protein 1) (Protein MAATS1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) axonemal central apparatus assembly [GO:1904158]; cell differentiation [GO:0030154]; cilium movement [GO:0003341]; spermatogenesis [GO:0007283] GO:0003341; GO:0005739; GO:0005930; GO:0007283; GO:0030154; GO:0031514; GO:1904158 7006 XR_006392668.1 98 76 43 108 56 NA NA NA NA NA NA 7007 XM_029333407.2 622 109 341 0 25 P29144 0 Tripeptidyl-peptidase 2 (TPP-2) (EC 3.4.14.10) (Tripeptidyl aminopeptidase) (Tripeptidyl-peptidase II) (TPP-II) Homo sapiens (Human) cellular amino acid homeostasis [GO:0080144]; protein polyubiquitination [GO:0000209]; proteolysis [GO:0006508] GO:0000209; GO:0004175; GO:0004177; GO:0004252; GO:0005654; GO:0005737; GO:0005829; GO:0006508; GO:0008240; GO:0016604; GO:0042802; GO:0080144 7008 XM_029343505.2 0 0 0 0 34 NA NA NA NA NA NA 7009 XM_029345821.2 34 0 39 0 55 Q96LD8 3.07e-53 Sentrin-specific protease 8 (EC 3.4.22.-) (Deneddylase-1) (NEDD8-specific protease 1) (Protease, cysteine 2) (Sentrin/SUMO-specific protease SENP8) Homo sapiens (Human) post-translational protein modification [GO:0043687]; protein deneddylation [GO:0000338]; protein deubiquitination [GO:0016579] GO:0000338; GO:0005829; GO:0008234; GO:0016579; GO:0019784; GO:0043687 7010 XM_029337594.2 0 107 176 184 25 Q7Z2Z2 0 Elongation factor-like GTPase 1 (Elongation factor Tu GTP-binding domain-containing protein 1) (Elongation factor-like 1) (Protein FAM42A) Homo sapiens (Human) cytosolic ribosome assembly [GO:0042256]; GTP metabolic process [GO:0046039] GO:0003746; GO:0003924; GO:0005525; GO:0042256; GO:0043022; GO:0046039; GO:1990904 7011 XR_003825557.2 6 5 0 2 2 NA NA NA NA NA NA 7012 XM_044322146.1 188 380 236 206 215 Q9DCC4 1.01e-75 Pyrroline-5-carboxylate reductase 3 (P5C reductase 3) (P5CR 3) (EC 1.5.1.2) (Pyrroline-5-carboxylate reductase-like protein) Mus musculus (Mouse) cytidine deamination [GO:0009972]; L-proline biosynthetic process [GO:0055129] GO:0004126; GO:0004735; GO:0005829; GO:0009972; GO:0045171; GO:0055129; GO:0072686 7013 XM_044308810.1 1 4 26 11 1 NA NA NA NA NA NA 7014 XM_044309828.1 39 19 31 23 41 NA NA NA NA NA NA 7015 XR_006396979.1 0 0 0 2 7 NA NA NA NA NA NA 7016 XM_044323948.1 1526 2627 1867 1782 1014 Q60803 1.31e-100 TNF receptor-associated factor 3 (EC 2.3.2.27) (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (RING-type E3 ubiquitin transferase TRAF3) Mus musculus (Mouse) apoptotic process [GO:0006915]; innate immune response [GO:0045087]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of JNK cascade [GO:0046330]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of cytokine production [GO:0001817]; regulation of defense response to virus [GO:0050688]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of interferon-beta production [GO:0032648]; regulation of proteolysis [GO:0030162]; Toll signaling pathway [GO:0008063]; toll-like receptor signaling pathway [GO:0002224]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0001817; GO:0002224; GO:0005164; GO:0005739; GO:0005768; GO:0006915; GO:0008063; GO:0008270; GO:0009898; GO:0016740; GO:0019901; GO:0019903; GO:0030162; GO:0031625; GO:0031996; GO:0032088; GO:0032648; GO:0033209; GO:0035631; GO:0042802; GO:0042981; GO:0043122; GO:0045087; GO:0046330; GO:0050688; GO:0070534 7017 XM_029338392.2 667 510 422 644 501 NA NA NA NA NA NA 7018 XR_006394636.1 49 10 38 45 53 NA NA NA NA NA NA 7019 XM_044321847.1 1613 644 1110 1399 1840 Q07113 0 Cation-independent mannose-6-phosphate receptor (CI Man-6-P receptor) (CI-MPR) (M6PR) (300 kDa mannose 6-phosphate receptor) (MPR 300) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (CD antigen CD222) Mus musculus (Mouse) animal organ regeneration [GO:0031100]; G protein-coupled receptor signaling pathway [GO:0007186]; liver development [GO:0001889]; lysosomal transport [GO:0007041]; positive regulation by host of viral process [GO:0044794]; positive regulation of apoptotic process [GO:0043065]; post-embryonic development [GO:0009791]; regulation of apoptotic process [GO:0042981]; response to retinoic acid [GO:0032526]; response to tetrachloromethane [GO:1904772]; spermatogenesis [GO:0007283] GO:0000139; GO:0001889; GO:0001965; GO:0001972; GO:0005520; GO:0005537; GO:0005615; GO:0005634; GO:0005641; GO:0005768; GO:0005769; GO:0005770; GO:0005794; GO:0005802; GO:0005886; GO:0007041; GO:0007186; GO:0007283; GO:0009791; GO:0009986; GO:0010008; GO:0016020; GO:0019899; GO:0030118; GO:0030139; GO:0030140; GO:0031100; GO:0031995; GO:0032526; GO:0038023; GO:0042802; GO:0042981; GO:0043065; GO:0044794; GO:0048471; GO:0051219; GO:1904772; GO:1905394 7020 XM_044321847.1 1613 644 1110 1399 1840 Q07113 2.52e-145 Cation-independent mannose-6-phosphate receptor (CI Man-6-P receptor) (CI-MPR) (M6PR) (300 kDa mannose 6-phosphate receptor) (MPR 300) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (CD antigen CD222) Mus musculus (Mouse) animal organ regeneration [GO:0031100]; G protein-coupled receptor signaling pathway [GO:0007186]; liver development [GO:0001889]; lysosomal transport [GO:0007041]; positive regulation by host of viral process [GO:0044794]; positive regulation of apoptotic process [GO:0043065]; post-embryonic development [GO:0009791]; regulation of apoptotic process [GO:0042981]; response to retinoic acid [GO:0032526]; response to tetrachloromethane [GO:1904772]; spermatogenesis [GO:0007283] GO:0000139; GO:0001889; GO:0001965; GO:0001972; GO:0005520; GO:0005537; GO:0005615; GO:0005634; GO:0005641; GO:0005768; GO:0005769; GO:0005770; GO:0005794; GO:0005802; GO:0005886; GO:0007041; GO:0007186; GO:0007283; GO:0009791; GO:0009986; GO:0010008; GO:0016020; GO:0019899; GO:0030118; GO:0030139; GO:0030140; GO:0031100; GO:0031995; GO:0032526; GO:0038023; GO:0042802; GO:0042981; GO:0043065; GO:0044794; GO:0048471; GO:0051219; GO:1904772; GO:1905394 7021 XM_044321847.1 1613 644 1110 1399 1840 Q07113 7.77e-97 Cation-independent mannose-6-phosphate receptor (CI Man-6-P receptor) (CI-MPR) (M6PR) (300 kDa mannose 6-phosphate receptor) (MPR 300) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (CD antigen CD222) Mus musculus (Mouse) animal organ regeneration [GO:0031100]; G protein-coupled receptor signaling pathway [GO:0007186]; liver development [GO:0001889]; lysosomal transport [GO:0007041]; positive regulation by host of viral process [GO:0044794]; positive regulation of apoptotic process [GO:0043065]; post-embryonic development [GO:0009791]; regulation of apoptotic process [GO:0042981]; response to retinoic acid [GO:0032526]; response to tetrachloromethane [GO:1904772]; spermatogenesis [GO:0007283] GO:0000139; GO:0001889; GO:0001965; GO:0001972; GO:0005520; GO:0005537; GO:0005615; GO:0005634; GO:0005641; GO:0005768; GO:0005769; GO:0005770; GO:0005794; GO:0005802; GO:0005886; GO:0007041; GO:0007186; GO:0007283; GO:0009791; GO:0009986; GO:0010008; GO:0016020; GO:0019899; GO:0030118; GO:0030139; GO:0030140; GO:0031100; GO:0031995; GO:0032526; GO:0038023; GO:0042802; GO:0042981; GO:0043065; GO:0044794; GO:0048471; GO:0051219; GO:1904772; GO:1905394 7022 XM_044321847.1 1613 644 1110 1399 1840 Q07113 1.5e-78 Cation-independent mannose-6-phosphate receptor (CI Man-6-P receptor) (CI-MPR) (M6PR) (300 kDa mannose 6-phosphate receptor) (MPR 300) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (CD antigen CD222) Mus musculus (Mouse) animal organ regeneration [GO:0031100]; G protein-coupled receptor signaling pathway [GO:0007186]; liver development [GO:0001889]; lysosomal transport [GO:0007041]; positive regulation by host of viral process [GO:0044794]; positive regulation of apoptotic process [GO:0043065]; post-embryonic development [GO:0009791]; regulation of apoptotic process [GO:0042981]; response to retinoic acid [GO:0032526]; response to tetrachloromethane [GO:1904772]; spermatogenesis [GO:0007283] GO:0000139; GO:0001889; GO:0001965; GO:0001972; GO:0005520; GO:0005537; GO:0005615; GO:0005634; GO:0005641; GO:0005768; GO:0005769; GO:0005770; GO:0005794; GO:0005802; GO:0005886; GO:0007041; GO:0007186; GO:0007283; GO:0009791; GO:0009986; GO:0010008; GO:0016020; GO:0019899; GO:0030118; GO:0030139; GO:0030140; GO:0031100; GO:0031995; GO:0032526; GO:0038023; GO:0042802; GO:0042981; GO:0043065; GO:0044794; GO:0048471; GO:0051219; GO:1904772; GO:1905394 7023 XM_044321847.1 1613 644 1110 1399 1840 Q07113 1.12e-36 Cation-independent mannose-6-phosphate receptor (CI Man-6-P receptor) (CI-MPR) (M6PR) (300 kDa mannose 6-phosphate receptor) (MPR 300) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (CD antigen CD222) Mus musculus (Mouse) animal organ regeneration [GO:0031100]; G protein-coupled receptor signaling pathway [GO:0007186]; liver development [GO:0001889]; lysosomal transport [GO:0007041]; positive regulation by host of viral process [GO:0044794]; positive regulation of apoptotic process [GO:0043065]; post-embryonic development [GO:0009791]; regulation of apoptotic process [GO:0042981]; response to retinoic acid [GO:0032526]; response to tetrachloromethane [GO:1904772]; spermatogenesis [GO:0007283] GO:0000139; GO:0001889; GO:0001965; GO:0001972; GO:0005520; GO:0005537; GO:0005615; GO:0005634; GO:0005641; GO:0005768; GO:0005769; GO:0005770; GO:0005794; GO:0005802; GO:0005886; GO:0007041; GO:0007186; GO:0007283; GO:0009791; GO:0009986; GO:0010008; GO:0016020; GO:0019899; GO:0030118; GO:0030139; GO:0030140; GO:0031100; GO:0031995; GO:0032526; GO:0038023; GO:0042802; GO:0042981; GO:0043065; GO:0044794; GO:0048471; GO:0051219; GO:1904772; GO:1905394 7024 XM_029330422.2 8 0 0 0 24 Q9EQD2 8.46e-38 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 7025 XM_044308013.1 793 821 725 728 985 NA NA NA NA NA NA 7026 XM_029346017.2 1655 331 366 1130 544 O42127 9.84e-73 Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) Xenopus laevis (African clawed frog) apoptotic process [GO:0006915]; positive regulation of cell population proliferation [GO:0008284] GO:0005007; GO:0005524; GO:0005886; GO:0006915; GO:0008284 7027 XR_003823915.2 67 16 0 35 0 Q8BLA8 3.8e-32 Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Wasabi receptor) Mus musculus (Mouse) calcium ion transmembrane import into cytosol [GO:0097553]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cell surface receptor signaling pathway [GO:0007166]; cellular calcium ion homeostasis [GO:0006874]; cellular response to carbon dioxide [GO:0071244]; cellular response to cold [GO:0070417]; cellular response to heat [GO:0034605]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to organic substance [GO:0071310]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; positive regulation of anion transport [GO:1903793]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of sensory perception of pain [GO:1904058]; protein homotetramerization [GO:0051289]; regulation of blood circulation [GO:1903522]; regulation of neuronal action potential [GO:0098908]; response to cold [GO:0009409]; response to hydrogen peroxide [GO:0042542]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; sensory perception of pain [GO:0019233]; thermoception [GO:0050955]; urinary bladder smooth muscle contraction [GO:0014832] GO:0005216; GO:0005245; GO:0005262; GO:0005886; GO:0006816; GO:0006874; GO:0007166; GO:0009409; GO:0009410; GO:0010033; GO:0014070; GO:0014832; GO:0015267; GO:0015278; GO:0016020; GO:0016324; GO:0019233; GO:0030424; GO:0032421; GO:0034605; GO:0035774; GO:0042542; GO:0042802; GO:0048265; GO:0050955; GO:0050966; GO:0050968; GO:0050974; GO:0051289; GO:0070301; GO:0070417; GO:0070588; GO:0071244; GO:0071310; GO:0097553; GO:0097604; GO:0098908; GO:1903522; GO:1903793; GO:1904058; GO:1990760 7028 XR_003823915.2 67 16 0 35 0 Q8BLA8 3.8e-32 Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Wasabi receptor) Mus musculus (Mouse) calcium ion transmembrane import into cytosol [GO:0097553]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cell surface receptor signaling pathway [GO:0007166]; cellular calcium ion homeostasis [GO:0006874]; cellular response to carbon dioxide [GO:0071244]; cellular response to cold [GO:0070417]; cellular response to heat [GO:0034605]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to organic substance [GO:0071310]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; positive regulation of anion transport [GO:1903793]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of sensory perception of pain [GO:1904058]; protein homotetramerization [GO:0051289]; regulation of blood circulation [GO:1903522]; regulation of neuronal action potential [GO:0098908]; response to cold [GO:0009409]; response to hydrogen peroxide [GO:0042542]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; sensory perception of pain [GO:0019233]; thermoception [GO:0050955]; urinary bladder smooth muscle contraction [GO:0014832] GO:0005216; GO:0005245; GO:0005262; GO:0005886; GO:0006816; GO:0006874; GO:0007166; GO:0009409; GO:0009410; GO:0010033; GO:0014070; GO:0014832; GO:0015267; GO:0015278; GO:0016020; GO:0016324; GO:0019233; GO:0030424; GO:0032421; GO:0034605; GO:0035774; GO:0042542; GO:0042802; GO:0048265; GO:0050955; GO:0050966; GO:0050968; GO:0050974; GO:0051289; GO:0070301; GO:0070417; GO:0070588; GO:0071244; GO:0071310; GO:0097553; GO:0097604; GO:0098908; GO:1903522; GO:1903793; GO:1904058; GO:1990760 7029 XM_044325187.1 22 26 18 26 91 O15439 0 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 7030 XM_044318481.1 172 6 93 132 100 Q92485 1.24e-136 Acid sphingomyelinase-like phosphodiesterase 3b (ASM-like phosphodiesterase 3b) (EC 3.1.4.-) Homo sapiens (Human) inflammatory response [GO:0006954]; innate immune response [GO:0045087]; membrane lipid catabolic process [GO:0046466]; negative regulation of inflammatory response [GO:0050728]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; sphingomyelin catabolic process [GO:0006685] GO:0004767; GO:0005615; GO:0005886; GO:0006685; GO:0006954; GO:0008081; GO:0008270; GO:0016798; GO:0034122; GO:0045087; GO:0046466; GO:0050728; GO:0070062 7031 XM_044320496.1 351 1226 203 922 1093 NA NA NA NA NA NA 7032 XR_006397280.1 5 58 31 10 68 NA NA NA NA NA NA 7033 XR_003823235.2 88 136 33 207 42 NA NA NA NA NA NA 7034 XM_029335364.2 333 122 0 0 81 P30884 3.36e-76 Bone morphogenetic protein 2-B (BMP-2-II) Xenopus laevis (African clawed frog) cartilage development [GO:0051216]; cell differentiation [GO:0030154]; ossification [GO:0001503] GO:0001503; GO:0005125; GO:0005615; GO:0008083; GO:0030154; GO:0051216 7035 XR_006395651.1 457 368 312 442 143 NA NA NA NA NA NA 7036 XM_029341502.2 0 54 21 46 44 NA NA NA NA NA NA 7037 XR_006391351.1 461 467 301 357 506 NA NA NA NA NA NA 7038 XM_044321777.1 296 77 0 1 0 NA NA NA NA NA NA 7039 XM_044310548.1 0 0 6 0 5 NA NA NA NA NA NA 7040 XM_044321273.1 573 161 168 202 23 NA NA NA NA NA NA 7041 XR_006395792.1 98 462 110 545 295 NA NA NA NA NA NA 7042 XM_029357325.2 20 71 264 41 328 Q6VAB6 9.41e-85 Kinase suppressor of Ras 2 (hKSR2) (EC 2.7.11.1) Homo sapiens (Human) calcium-mediated signaling [GO:0019722]; positive regulation of cold-induced thermogenesis [GO:0120162]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; signal transduction [GO:0007165] GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006468; GO:0007165; GO:0007265; GO:0019722; GO:0046872; GO:0106310; GO:0120162 7043 XM_029357325.2 20 71 264 41 328 Q6VAB6 3.09e-22 Kinase suppressor of Ras 2 (hKSR2) (EC 2.7.11.1) Homo sapiens (Human) calcium-mediated signaling [GO:0019722]; positive regulation of cold-induced thermogenesis [GO:0120162]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; signal transduction [GO:0007165] GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006468; GO:0007165; GO:0007265; GO:0019722; GO:0046872; GO:0106310; GO:0120162 7044 XR_006396434.1 213 109 136 683 142 Q8K2X2 1.87e-23 RNA-binding protein 48 Mus musculus (Mouse) NA GO:0003723; GO:0005654 7045 XM_044307988.1 0 0 5 0 13 NA NA NA NA NA NA 7046 XM_029337110.2 2289 652 870 2064 188 A2RV80 5.09e-70 GRAM domain-containing protein 4 Xenopus laevis (African clawed frog) apoptotic process [GO:0006915] GO:0005789; GO:0006915; GO:0031966 7047 XM_044326069.1 3148 3529 1830 2051 2014 Q9Z1N1 1.48e-140 Fructose-1,6-bisphosphatase isozyme 2 (FBPase 2) (EC 3.1.3.11) (D-fructose-1,6-bisphosphate 1-phosphohydrolase 2) (Muscle FBPase) Rattus norvegicus (Rat) fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose 6-phosphate metabolic process [GO:0006002]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; sucrose biosynthetic process [GO:0005986] GO:0005634; GO:0005737; GO:0005829; GO:0005986; GO:0006000; GO:0006002; GO:0006094; GO:0030018; GO:0030388; GO:0042132; GO:0042802; GO:0046872; GO:0070161 7048 XM_044321522.1 9 0 0 0 4 NA NA NA NA NA NA 7049 XM_044321820.1 12 25 21 6 5 NA NA NA NA NA NA 7050 XR_006396516.1 45 4 18 34 39 NA NA NA NA NA NA 7051 XM_044321118.1 2218 1025 1581 1746 1846 NA NA NA NA NA NA 7052 XM_044314065.1 31 38 21 28 34 NA NA NA NA NA NA 7053 XM_044315399.1 10 0 2 4 1 NA NA NA NA NA NA 7054 XM_044316377.1 687 746 266 599 555 NA NA NA NA NA NA 7055 XM_029343433.2 867 1058 856 1387 1135 P52632 1.3e-109 Signal transducer and activator of transcription 5B Rattus norvegicus (Rat) activated T cell proliferation [GO:0050798]; acute-phase response [GO:0006953]; B cell differentiation [GO:0030183]; cell population proliferation [GO:0008283]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; cellular response to hormone stimulus [GO:0032870]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; development of secondary female sexual characteristics [GO:0046543]; development of secondary male sexual characteristics [GO:0046544]; erythrocyte differentiation [GO:0030218]; female pregnancy [GO:0007565]; gamma-delta T cell differentiation [GO:0042492]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; lactation [GO:0007595]; lipid storage [GO:0019915]; liver development [GO:0001889]; luteinization [GO:0001553]; lymphocyte differentiation [GO:0030098]; mast cell migration [GO:0097531]; mitotic cell cycle [GO:0000278]; myeloid cell apoptotic process [GO:0033028]; natural killer cell differentiation [GO:0001779]; natural killer cell mediated cytotoxicity [GO:0042267]; natural killer cell proliferation [GO:0001787]; negative regulation of apoptotic process [GO:0043066]; negative regulation of erythrocyte differentiation [GO:0045647]; negative regulation of myeloid cell apoptotic process [GO:0033033]; Peyer's patch development [GO:0048541]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of gamma-delta T cell differentiation [GO:0045588]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of lymphocyte differentiation [GO:0045621]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of natural killer cell differentiation [GO:0032825]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; progesterone metabolic process [GO:0042448]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of cell adhesion [GO:0030155]; regulation of cell population proliferation [GO:0042127]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell differentiation [GO:0030856]; regulation of multicellular organism growth [GO:0040014]; regulation of steroid metabolic process [GO:0019218]; regulation of transcription by RNA polymerase II [GO:0006357]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to interleukin-15 [GO:0070672]; response to interleukin-2 [GO:0070669]; response to interleukin-4 [GO:0070670]; response to lipopolysaccharide [GO:0032496]; response to peptide hormone [GO:0043434]; sex differentiation [GO:0007548]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; taurine metabolic process [GO:0019530]; transcription by RNA polymerase II [GO:0006366] GO:0000278; GO:0000978; GO:0000981; GO:0001228; GO:0001553; GO:0001666; GO:0001779; GO:0001787; GO:0001889; GO:0003677; GO:0003682; GO:0003690; GO:0003700; GO:0005634; GO:0005737; GO:0005829; GO:0006355; GO:0006357; GO:0006366; GO:0006952; GO:0006953; GO:0007259; GO:0007548; GO:0007565; GO:0007595; GO:0008283; GO:0008284; GO:0010628; GO:0014911; GO:0019218; GO:0019221; GO:0019530; GO:0019915; GO:0030098; GO:0030155; GO:0030183; GO:0030218; GO:0030856; GO:0032355; GO:0032496; GO:0032743; GO:0032819; GO:0032825; GO:0032870; GO:0033028; GO:0033033; GO:0033077; GO:0035259; GO:0040014; GO:0040018; GO:0042104; GO:0042127; GO:0042267; GO:0042448; GO:0042492; GO:0042802; GO:0042803; GO:0043029; GO:0043066; GO:0043434; GO:0043565; GO:0045471; GO:0045579; GO:0045588; GO:0045621; GO:0045647; GO:0045648; GO:0045931; GO:0045944; GO:0045954; GO:0046543; GO:0046544; GO:0046983; GO:0048541; GO:0048661; GO:0050729; GO:0050798; GO:0060397; GO:0070669; GO:0070670; GO:0070672; GO:0071363; GO:0071364; GO:0090271; GO:0097531; GO:0140297 7056 XM_044328116.1 938 749 813 874 1077 Q80U30 0 Protein CLEC16A Mus musculus (Mouse) autophagy [GO:0006914]; cellular response to starvation [GO:0009267]; endosomal transport [GO:0016197]; endosome to lysosome transport [GO:0008333]; negative regulation of autophagosome maturation [GO:1901097]; negative regulation of macroautophagy by TORC1 signaling [GO:1904766]; negative regulation of mitophagy [GO:1901525]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; positive regulation of autophagosome maturation [GO:1901098]; positive regulation of TORC1 signaling [GO:1904263]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of autophagosome maturation [GO:1901096] GO:0005794; GO:0005829; GO:0006914; GO:0008333; GO:0009267; GO:0016020; GO:0016197; GO:0031982; GO:0032435; GO:0036020; GO:0043161; GO:1901096; GO:1901097; GO:1901098; GO:1901525; GO:1904263; GO:1904766 7057 XM_044325724.1 63 3 47 46 346 NA NA NA NA NA NA 7058 XM_044322336.1 90 35 79 59 178 NA NA NA NA NA NA 7059 XM_029328932.2 63 0 0 73 0 Q8BLA8 1.98e-126 Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Wasabi receptor) Mus musculus (Mouse) calcium ion transmembrane import into cytosol [GO:0097553]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cell surface receptor signaling pathway [GO:0007166]; cellular calcium ion homeostasis [GO:0006874]; cellular response to carbon dioxide [GO:0071244]; cellular response to cold [GO:0070417]; cellular response to heat [GO:0034605]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to organic substance [GO:0071310]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; positive regulation of anion transport [GO:1903793]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of sensory perception of pain [GO:1904058]; protein homotetramerization [GO:0051289]; regulation of blood circulation [GO:1903522]; regulation of neuronal action potential [GO:0098908]; response to cold [GO:0009409]; response to hydrogen peroxide [GO:0042542]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; sensory perception of pain [GO:0019233]; thermoception [GO:0050955]; urinary bladder smooth muscle contraction [GO:0014832] GO:0005216; GO:0005245; GO:0005262; GO:0005886; GO:0006816; GO:0006874; GO:0007166; GO:0009409; GO:0009410; GO:0010033; GO:0014070; GO:0014832; GO:0015267; GO:0015278; GO:0016020; GO:0016324; GO:0019233; GO:0030424; GO:0032421; GO:0034605; GO:0035774; GO:0042542; GO:0042802; GO:0048265; GO:0050955; GO:0050966; GO:0050968; GO:0050974; GO:0051289; GO:0070301; GO:0070417; GO:0070588; GO:0071244; GO:0071310; GO:0097553; GO:0097604; GO:0098908; GO:1903522; GO:1903793; GO:1904058; GO:1990760 7060 XR_006395666.1 23 20 58 37 5 NA NA NA NA NA NA 7061 XM_044308128.1 38 4 20 24 0 P30975 6.22e-24 Tachykinin-like peptides receptor 99D (Tachykinin-like receptor at 99D) (dTKR) Drosophila melanogaster (Fruit fly) detection of chemical stimulus involved in sensory perception of smell [GO:0050911]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; neuropeptide signaling pathway [GO:0007218]; olfactory behavior [GO:0042048]; positive regulation of sensory perception of pain [GO:1904058]; tachykinin receptor signaling pathway [GO:0007217] GO:0004995; GO:0005886; GO:0007186; GO:0007217; GO:0007218; GO:0008188; GO:0016020; GO:0042048; GO:0050805; GO:0050911; GO:1904058 7062 XR_006396132.1 0 50 66 20 326 NA NA NA NA NA NA 7063 XR_006394121.1 0 3 35 34 16 NA NA NA NA NA NA 7064 XM_044322295.1 33 38 6 7 23 P29146 0 PC3-like endoprotease variant A (EC 3.4.21.-) (SPC3) Hydra vulgaris (Hydra) (Hydra attenuata) proteolysis [GO:0006508] GO:0004252; GO:0006508 7065 XM_044326097.1 0 7 4 12 12 NA NA NA NA NA NA 7066 XM_044316154.1 405 375 305 488 370 P16157 1.76e-49 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 7067 XM_044316154.1 405 375 305 488 370 P16157 1.22e-47 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 7068 XM_044316154.1 405 375 305 488 370 P16157 2.07e-45 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 7069 XM_044316154.1 405 375 305 488 370 P16157 7.54e-44 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 7070 XM_044316154.1 405 375 305 488 370 P16157 8.6e-44 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 7071 XM_044316154.1 405 375 305 488 370 P16157 5.62e-34 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 7072 XM_044316154.1 405 375 305 488 370 P16157 2.32e-29 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 7073 XM_044316154.1 405 375 305 488 370 P16157 2.32e-29 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 7074 XM_029323687.2 1081 2817 1028 1892 1549 NA NA NA NA NA NA 7075 XR_006392947.1 41 2 25 5 151 NA NA NA NA NA NA 7076 XM_029334613.2 3282 2849 1917 2925 2741 Q91WG5 1.09e-127 5'-AMP-activated protein kinase subunit gamma-2 (AMPK gamma2) (AMPK subunit gamma-2) Mus musculus (Mouse) cellular response to glucose starvation [GO:0042149]; cellular response to nutrient levels [GO:0031669]; fatty acid biosynthetic process [GO:0006633]; glycogen metabolic process [GO:0005977]; intracellular signal transduction [GO:0035556]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein kinase activity [GO:0045860]; protein phosphorylation [GO:0006468]; regulation of catalytic activity [GO:0050790]; regulation of fatty acid metabolic process [GO:0019217]; regulation of glycolytic process [GO:0006110] GO:0004679; GO:0004862; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005977; GO:0006110; GO:0006468; GO:0006469; GO:0006633; GO:0008603; GO:0008607; GO:0010800; GO:0016208; GO:0019217; GO:0019887; GO:0019901; GO:0030295; GO:0031588; GO:0031669; GO:0035556; GO:0042149; GO:0043531; GO:0045860; GO:0050790 7077 XM_029341414.2 236 167 132 210 238 Q6L8S8 2.83e-58 Beta-1,4-N-acetylgalactosaminyltransferase 3 (Beta4GalNAc-T3) (Beta4GalNAcT3) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase III) (N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 2) (NGalNAc-T2) Mus musculus (Mouse) chondroitin sulfate biosynthetic process [GO:0030206] GO:0005794; GO:0008376; GO:0030206; GO:0032580; GO:0033842; GO:0043231; GO:0047238 7078 XM_029342219.2 3673 3480 2180 3593 3123 Q8R4F0 1.86e-109 Mucolipin-3 (Transient receptor potential channel mucolipin 3) (TRPML3) Mus musculus (Mouse) inner ear auditory receptor cell differentiation [GO:0042491]; locomotory behavior [GO:0007626] GO:0000421; GO:0005737; GO:0005765; GO:0005886; GO:0007626; GO:0008289; GO:0016020; GO:0031901; GO:0031902; GO:0042491; GO:0060171; GO:0072345 7079 XM_044308121.1 0 35 0 0 15 NA NA NA NA NA NA 7080 XM_044324931.1 31 79 115 59 74 NA NA NA NA NA NA 7081 XM_029333222.2 0 29 0 0 0 O75899 3.86e-91 Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51) (HG20) Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway [GO:0007186]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; neuron-glial cell signaling [GO:0150099]; synaptic transmission, GABAergic [GO:0051932] GO:0004888; GO:0004965; GO:0005737; GO:0005886; GO:0007186; GO:0007193; GO:0007194; GO:0007214; GO:0007268; GO:0038039; GO:0043005; GO:0045211; GO:0046982; GO:0051932; GO:0150099; GO:1902710; GO:1902712 7082 XM_044307022.1 7 0 0 2 0 P0DP43 8.37e-37 Cation channel sperm-associated auxiliary subunit epsilon (CatSper-epsilon) (CatSperepsilon) (C1orf101-like protein) Mus musculus (Mouse) flagellated sperm motility [GO:0030317]; sperm capacitation [GO:0048240] GO:0030317; GO:0036128; GO:0048240; GO:0097228 7083 XM_029342083.2 614 480 504 426 625 Q6P2B1 0 Transportin-3 Mus musculus (Mouse) protein import into nucleus [GO:0006606] GO:0005635; GO:0005642; GO:0005737; GO:0006606; GO:0031267; GO:0042802; GO:0043231 7084 XM_029329553.2 402 219 181 388 426 Q99N01 4.81e-96 Solute carrier organic anion transporter family member 4A1 (Organic anion-transporting polypeptide E) (OATP-E) (Sodium-independent organic anion transporter E) (Solute carrier family 21 member 12) Rattus norvegicus (Rat) sodium-independent organic anion transport [GO:0043252]; thyroid hormone metabolic process [GO:0042403] GO:0005886; GO:0008514; GO:0015132; GO:0015347; GO:0015349; GO:0042403; GO:0043252 7085 XM_029341486.2 132 76 43 112 273 Q76NI1 3.86e-73 Kinase non-catalytic C-lobe domain-containing protein 1 (KIND domain-containing protein 1) (Cerebral protein 9) (Protein very KIND) (v-KIND) (Ras-GEF domain-containing family member 2) Homo sapiens (Human) cerebellar granule cell differentiation [GO:0021707]; positive regulation of protein phosphorylation [GO:0001934]; regulation of dendrite development [GO:0050773]; regulation of dendrite morphogenesis [GO:0048814]; small GTPase mediated signal transduction [GO:0007264] GO:0001934; GO:0005085; GO:0007264; GO:0021707; GO:0030425; GO:0032045; GO:0043025; GO:0043204; GO:0048814; GO:0050773 7086 XM_044316333.1 500 33 15 372 139 NA NA NA NA NA NA 7087 XR_006396910.1 7 0 10 60 27 NA NA NA NA NA NA 7088 XM_029356680.2 2602 2243 1510 2232 3009 Q9D4H7 5.11e-91 LON peptidase N-terminal domain and RING finger protein 3 (RING finger protein 127) Mus musculus (Mouse) NA GO:0005737; GO:0046872; GO:0061630 7089 XR_006392075.1 48 6 33 36 18 NA NA NA NA NA NA 7090 XM_029328545.2 21166 26488 18903 35411 31029 Q5R8J8 2.49e-88 DnaJ homolog subfamily B member 4 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) protein folding [GO:0006457] GO:0001671; GO:0005737; GO:0005886; GO:0006457; GO:0051082 7091 XM_044312215.1 227 97 0 150 832 NA NA NA NA NA NA 7092 XM_029324068.2 199 90 161 244 145 Q96L42 0 Potassium voltage-gated channel subfamily H member 8 (ELK1) (hElk1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (Voltage-gated potassium channel subunit Kv12.1) Homo sapiens (Human) potassium ion transmembrane transport [GO:0071805]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391] GO:0005249; GO:0005886; GO:0034765; GO:0042391; GO:0071805 7093 XM_029348594.2 653 850 366 503 422 P59722 3.23e-69 Egl nine homolog 1 (EC 1.14.11.29) (Hypoxia-inducible factor prolyl hydroxylase 2) (HIF-PH2) (HIF-prolyl hydroxylase 2) (HPH-2) (Prolyl hydroxylase domain-containing protein 2) (PHD2) Rattus norvegicus (Rat) cardiac muscle tissue morphogenesis [GO:0055008]; cellular iron ion homeostasis [GO:0006879]; cellular oxygen homeostasis [GO:0032364]; cellular response to hypoxia [GO:0071456]; heart trabecula formation [GO:0060347]; labyrinthine layer development [GO:0060711]; negative regulation of CAMKK-AMPK signaling cascade [GO:1905290]; negative regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051344]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; positive regulation of apoptotic process [GO:0043065]; positive regulation of neuron death [GO:1901216]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of angiogenesis [GO:0045765]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of neuron death [GO:1901214]; regulation of postsynapse organization [GO:0099175]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation protein catabolic process at postsynapse [GO:0140252]; response to hypoxia [GO:0001666]; response to nitric oxide [GO:0071731]; ventricular septum morphogenesis [GO:0060412] GO:0001666; GO:0005634; GO:0005737; GO:0005829; GO:0006879; GO:0008198; GO:0014069; GO:0016706; GO:0018401; GO:0019899; GO:0031418; GO:0031543; GO:0031545; GO:0032364; GO:0043065; GO:0043433; GO:0045765; GO:0045944; GO:0051344; GO:0055008; GO:0060347; GO:0060412; GO:0060711; GO:0071456; GO:0071731; GO:0098978; GO:0099159; GO:0099175; GO:0099576; GO:0140252; GO:1901214; GO:1901216; GO:1905290 7094 XM_029326884.2 1285 886 485 1347 952 Q6JHU9 0 Histone lysine acetyltransferase CREBBP (EC 2.3.1.48) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-) Rattus norvegicus (Rat) behavioral response to cocaine [GO:0048148]; cell population proliferation [GO:0008283]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to UV [GO:0034644]; cellular response to virus [GO:0098586]; face morphogenesis [GO:0060325]; germ-line stem cell population maintenance [GO:0030718]; histone acetylation [GO:0016573]; histone glutamine methylation [GO:1990258]; histone modification [GO:0016570]; long-term memory [GO:0007616]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription by RNA polymerase I [GO:0016479]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral process [GO:0048525]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; regulation of DNA-templated transcription [GO:0006355]; response to interleukin-1 [GO:0070555]; response to ischemia [GO:0002931]; rhythmic process [GO:0048511] GO:0000122; GO:0000123; GO:0000785; GO:0000940; GO:0000977; GO:0001093; GO:0001223; GO:0002039; GO:0002931; GO:0003677; GO:0003682; GO:0003684; GO:0003713; GO:0003714; GO:0004402; GO:0005634; GO:0005654; GO:0005667; GO:0005737; GO:0006355; GO:0006473; GO:0007616; GO:0008140; GO:0008270; GO:0008283; GO:0010628; GO:0016407; GO:0016479; GO:0016570; GO:0016573; GO:0016604; GO:0018076; GO:0019904; GO:0030511; GO:0030718; GO:0031490; GO:0031648; GO:0032688; GO:0032793; GO:0032991; GO:0034644; GO:0035729; GO:0042975; GO:0043426; GO:0045893; GO:0045944; GO:0046332; GO:0048148; GO:0048511; GO:0048525; GO:0060090; GO:0060325; GO:0060355; GO:0060999; GO:0061629; GO:0061733; GO:0070555; GO:0090575; GO:0097718; GO:0098586; GO:0140297; GO:1900087; GO:1901224; GO:1990258 7095 XM_029326884.2 1285 886 485 1347 952 Q6JHU9 2.06e-71 Histone lysine acetyltransferase CREBBP (EC 2.3.1.48) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-) Rattus norvegicus (Rat) behavioral response to cocaine [GO:0048148]; cell population proliferation [GO:0008283]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to UV [GO:0034644]; cellular response to virus [GO:0098586]; face morphogenesis [GO:0060325]; germ-line stem cell population maintenance [GO:0030718]; histone acetylation [GO:0016573]; histone glutamine methylation [GO:1990258]; histone modification [GO:0016570]; long-term memory [GO:0007616]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription by RNA polymerase I [GO:0016479]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral process [GO:0048525]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; regulation of DNA-templated transcription [GO:0006355]; response to interleukin-1 [GO:0070555]; response to ischemia [GO:0002931]; rhythmic process [GO:0048511] GO:0000122; GO:0000123; GO:0000785; GO:0000940; GO:0000977; GO:0001093; GO:0001223; GO:0002039; GO:0002931; GO:0003677; GO:0003682; GO:0003684; GO:0003713; GO:0003714; GO:0004402; GO:0005634; GO:0005654; GO:0005667; GO:0005737; GO:0006355; GO:0006473; GO:0007616; GO:0008140; GO:0008270; GO:0008283; GO:0010628; GO:0016407; GO:0016479; GO:0016570; GO:0016573; GO:0016604; GO:0018076; GO:0019904; GO:0030511; GO:0030718; GO:0031490; GO:0031648; GO:0032688; GO:0032793; GO:0032991; GO:0034644; GO:0035729; GO:0042975; GO:0043426; GO:0045893; GO:0045944; GO:0046332; GO:0048148; GO:0048511; GO:0048525; GO:0060090; GO:0060325; GO:0060355; GO:0060999; GO:0061629; GO:0061733; GO:0070555; GO:0090575; GO:0097718; GO:0098586; GO:0140297; GO:1900087; GO:1901224; GO:1990258 7096 XR_006395482.1 1 5 20 66 49 NA NA NA NA NA NA 7097 XM_029331267.2 323 300 175 481 585 Q5VWP2 2.29e-139 Terminal nucleotidyltransferase 5C (EC 2.7.7.19) (Non-canonical poly(A) polymerase FAM46C) Homo sapiens (Human) in utero embryonic development [GO:0001701]; mRNA stabilization [GO:0048255]; negative regulation of cell differentiation [GO:0045596] GO:0001701; GO:0003723; GO:0004652; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0045596; GO:0048255; GO:1990817 7098 XM_029345492.2 0 0 0 31 0 Q8N0W4 5.03e-78 Neuroligin-4, X-linked (Neuroligin X) (HNLX) Homo sapiens (Human) adult behavior [GO:0030534]; brainstem development [GO:0003360]; cell-cell junction organization [GO:0045216]; cerebellum development [GO:0021549]; chemical synaptic transmission [GO:0007268]; learning [GO:0007612]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of excitatory postsynaptic potential [GO:0090394]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; organ growth [GO:0035265]; postsynaptic membrane assembly [GO:0097104]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; social behavior [GO:0035176]; synapse organization [GO:0050808]; synaptic vesicle endocytosis [GO:0048488]; vocalization behavior [GO:0071625] GO:0003360; GO:0005886; GO:0007158; GO:0007268; GO:0007612; GO:0009986; GO:0016020; GO:0021549; GO:0030182; GO:0030425; GO:0030534; GO:0031404; GO:0035176; GO:0035265; GO:0038023; GO:0042043; GO:0042803; GO:0045202; GO:0045216; GO:0048488; GO:0050804; GO:0050808; GO:0050839; GO:0060076; GO:0071625; GO:0090394; GO:0097104; GO:0097105; GO:0097110; GO:0098793; GO:0098839; GO:0098983; GO:0098985; GO:0099054; GO:0099634 7099 XR_006392583.1 0 0 6 2 0 NA NA NA NA NA NA 7100 XM_029343916.2 0 111 112 139 39 Q96RW7 2.38e-70 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 7101 XM_029343916.2 0 111 112 139 39 Q96RW7 5.42e-66 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 7102 XM_029343916.2 0 111 112 139 39 Q96RW7 7.65e-65 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 7103 XM_029343916.2 0 111 112 139 39 Q96RW7 1.08e-63 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 7104 XM_029343916.2 0 111 112 139 39 Q96RW7 1.05e-62 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 7105 XM_029343916.2 0 111 112 139 39 Q96RW7 8.74e-52 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 7106 XM_029343916.2 0 111 112 139 39 Q96RW7 7.13e-49 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 7107 XM_029343916.2 0 111 112 139 39 Q96RW7 1.6e-48 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 7108 XM_029353723.2 50 165 15 240 115 Q20191 8.11e-50 Zinc metalloproteinase nas-13 (EC 3.4.24.-) (Nematode astacin 13) Caenorhabditis elegans proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0006508; GO:0008270 7109 XR_003825815.2 59 61 13 64 18 NA NA NA NA NA NA 7110 XR_006394363.1 102 20 59 105 136 Q17QR8 3.27e-33 Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease) Bos taurus (Bovine) NA GO:0004518; GO:0005634; GO:0005829; GO:0005886; GO:0034451; GO:0046872 7111 XM_044325284.1 447 567 2223 1444 3350 Q01484 0 Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin) Homo sapiens (Human) atrial cardiac muscle cell action potential [GO:0086014]; atrial cardiac muscle cell to AV node cell communication [GO:0086066]; atrial septum development [GO:0003283]; cellular calcium ion homeostasis [GO:0006874]; endocytosis [GO:0006897]; membrane depolarization during SA node cell action potential [GO:0086046]; paranodal junction assembly [GO:0030913]; positive regulation of calcium ion transmembrane transporter activity [GO:1901021]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cation channel activity [GO:2001259]; positive regulation of gene expression [GO:0010628]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to endoplasmic reticulum [GO:0070972]; protein localization to M-band [GO:0036309]; protein localization to organelle [GO:0033365]; protein localization to plasma membrane [GO:0072659]; protein localization to T-tubule [GO:0036371]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; regulation of atrial cardiac muscle cell action potential [GO:0098910]; regulation of calcium ion transmembrane transporter activity [GO:1901019]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of heart rate [GO:0002027]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of protein stability [GO:0031647]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of SA node cell action potential [GO:0098907]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; response to methylmercury [GO:0051597]; SA node cell action potential [GO:0086015]; SA node cell to atrial cardiac muscle cell communication [GO:0086070]; sarcoplasmic reticulum calcium ion transport [GO:0070296]; T-tubule organization [GO:0033292]; ventricular cardiac muscle cell action potential [GO:0086005] GO:0002027; GO:0003283; GO:0005200; GO:0005739; GO:0005764; GO:0005769; GO:0005829; GO:0005856; GO:0005886; GO:0006874; GO:0006897; GO:0008093; GO:0008104; GO:0010628; GO:0010881; GO:0010882; GO:0014704; GO:0015031; GO:0016323; GO:0016324; GO:0019899; GO:0019901; GO:0030018; GO:0030315; GO:0030507; GO:0030674; GO:0030913; GO:0031430; GO:0031647; GO:0031672; GO:0033292; GO:0033365; GO:0034394; GO:0036309; GO:0036371; GO:0042383; GO:0043005; GO:0043034; GO:0043268; GO:0044325; GO:0045121; GO:0045211; GO:0050821; GO:0051117; GO:0051279; GO:0051597; GO:0051924; GO:0051928; GO:0055037; GO:0055117; GO:0060307; GO:0070296; GO:0070972; GO:0072659; GO:0086004; GO:0086005; GO:0086014; GO:0086015; GO:0086046; GO:0086066; GO:0086070; GO:0086091; GO:0098907; GO:0098910; GO:0140031; GO:1901018; GO:1901019; GO:1901021; GO:2001259 7112 XM_044325284.1 447 567 2223 1444 3350 Q01484 1e-105 Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin) Homo sapiens (Human) atrial cardiac muscle cell action potential [GO:0086014]; atrial cardiac muscle cell to AV node cell communication [GO:0086066]; atrial septum development [GO:0003283]; cellular calcium ion homeostasis [GO:0006874]; endocytosis [GO:0006897]; membrane depolarization during SA node cell action potential [GO:0086046]; paranodal junction assembly [GO:0030913]; positive regulation of calcium ion transmembrane transporter activity [GO:1901021]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cation channel activity [GO:2001259]; positive regulation of gene expression [GO:0010628]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to endoplasmic reticulum [GO:0070972]; protein localization to M-band [GO:0036309]; protein localization to organelle [GO:0033365]; protein localization to plasma membrane [GO:0072659]; protein localization to T-tubule [GO:0036371]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; regulation of atrial cardiac muscle cell action potential [GO:0098910]; regulation of calcium ion transmembrane transporter activity [GO:1901019]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of heart rate [GO:0002027]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of protein stability [GO:0031647]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of SA node cell action potential [GO:0098907]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; response to methylmercury [GO:0051597]; SA node cell action potential [GO:0086015]; SA node cell to atrial cardiac muscle cell communication [GO:0086070]; sarcoplasmic reticulum calcium ion transport [GO:0070296]; T-tubule organization [GO:0033292]; ventricular cardiac muscle cell action potential [GO:0086005] GO:0002027; GO:0003283; GO:0005200; GO:0005739; GO:0005764; GO:0005769; GO:0005829; GO:0005856; GO:0005886; GO:0006874; GO:0006897; GO:0008093; GO:0008104; GO:0010628; GO:0010881; GO:0010882; GO:0014704; GO:0015031; GO:0016323; GO:0016324; GO:0019899; GO:0019901; GO:0030018; GO:0030315; GO:0030507; GO:0030674; GO:0030913; GO:0031430; GO:0031647; GO:0031672; GO:0033292; GO:0033365; GO:0034394; GO:0036309; GO:0036371; GO:0042383; GO:0043005; GO:0043034; GO:0043268; GO:0044325; GO:0045121; GO:0045211; GO:0050821; GO:0051117; GO:0051279; GO:0051597; GO:0051924; GO:0051928; GO:0055037; GO:0055117; GO:0060307; GO:0070296; GO:0070972; GO:0072659; GO:0086004; GO:0086005; GO:0086014; GO:0086015; GO:0086046; GO:0086066; GO:0086070; GO:0086091; GO:0098907; GO:0098910; GO:0140031; GO:1901018; GO:1901019; GO:1901021; GO:2001259 7113 XM_044325284.1 447 567 2223 1444 3350 Q01484 9.54e-104 Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin) Homo sapiens (Human) atrial cardiac muscle cell action potential [GO:0086014]; atrial cardiac muscle cell to AV node cell communication [GO:0086066]; atrial septum development [GO:0003283]; cellular calcium ion homeostasis [GO:0006874]; endocytosis [GO:0006897]; membrane depolarization during SA node cell action potential [GO:0086046]; paranodal junction assembly [GO:0030913]; positive regulation of calcium ion transmembrane transporter activity [GO:1901021]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cation channel activity [GO:2001259]; positive regulation of gene expression [GO:0010628]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to endoplasmic reticulum [GO:0070972]; protein localization to M-band [GO:0036309]; protein localization to organelle [GO:0033365]; protein localization to plasma membrane [GO:0072659]; protein localization to T-tubule [GO:0036371]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; regulation of atrial cardiac muscle cell action potential [GO:0098910]; regulation of calcium ion transmembrane transporter activity [GO:1901019]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of heart rate [GO:0002027]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of protein stability [GO:0031647]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of SA node cell action potential [GO:0098907]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; response to methylmercury [GO:0051597]; SA node cell action potential [GO:0086015]; SA node cell to atrial cardiac muscle cell communication [GO:0086070]; sarcoplasmic reticulum calcium ion transport [GO:0070296]; T-tubule organization [GO:0033292]; ventricular cardiac muscle cell action potential [GO:0086005] GO:0002027; GO:0003283; GO:0005200; GO:0005739; GO:0005764; GO:0005769; GO:0005829; GO:0005856; GO:0005886; GO:0006874; GO:0006897; GO:0008093; GO:0008104; GO:0010628; GO:0010881; GO:0010882; GO:0014704; GO:0015031; GO:0016323; GO:0016324; GO:0019899; GO:0019901; GO:0030018; GO:0030315; GO:0030507; GO:0030674; GO:0030913; GO:0031430; GO:0031647; GO:0031672; GO:0033292; GO:0033365; GO:0034394; GO:0036309; GO:0036371; GO:0042383; GO:0043005; GO:0043034; GO:0043268; GO:0044325; GO:0045121; GO:0045211; GO:0050821; GO:0051117; GO:0051279; GO:0051597; GO:0051924; GO:0051928; GO:0055037; GO:0055117; GO:0060307; GO:0070296; GO:0070972; GO:0072659; GO:0086004; GO:0086005; GO:0086014; GO:0086015; GO:0086046; GO:0086066; GO:0086070; GO:0086091; GO:0098907; GO:0098910; GO:0140031; GO:1901018; GO:1901019; GO:1901021; GO:2001259 7114 XM_044325284.1 447 567 2223 1444 3350 Q01484 2.1e-47 Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin) Homo sapiens (Human) atrial cardiac muscle cell action potential [GO:0086014]; atrial cardiac muscle cell to AV node cell communication [GO:0086066]; atrial septum development [GO:0003283]; cellular calcium ion homeostasis [GO:0006874]; endocytosis [GO:0006897]; membrane depolarization during SA node cell action potential [GO:0086046]; paranodal junction assembly [GO:0030913]; positive regulation of calcium ion transmembrane transporter activity [GO:1901021]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cation channel activity [GO:2001259]; positive regulation of gene expression [GO:0010628]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to endoplasmic reticulum [GO:0070972]; protein localization to M-band [GO:0036309]; protein localization to organelle [GO:0033365]; protein localization to plasma membrane [GO:0072659]; protein localization to T-tubule [GO:0036371]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; regulation of atrial cardiac muscle cell action potential [GO:0098910]; regulation of calcium ion transmembrane transporter activity [GO:1901019]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of heart rate [GO:0002027]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of protein stability [GO:0031647]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of SA node cell action potential [GO:0098907]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; response to methylmercury [GO:0051597]; SA node cell action potential [GO:0086015]; SA node cell to atrial cardiac muscle cell communication [GO:0086070]; sarcoplasmic reticulum calcium ion transport [GO:0070296]; T-tubule organization [GO:0033292]; ventricular cardiac muscle cell action potential [GO:0086005] GO:0002027; GO:0003283; GO:0005200; GO:0005739; GO:0005764; GO:0005769; GO:0005829; GO:0005856; GO:0005886; GO:0006874; GO:0006897; GO:0008093; GO:0008104; GO:0010628; GO:0010881; GO:0010882; GO:0014704; GO:0015031; GO:0016323; GO:0016324; GO:0019899; GO:0019901; GO:0030018; GO:0030315; GO:0030507; GO:0030674; GO:0030913; GO:0031430; GO:0031647; GO:0031672; GO:0033292; GO:0033365; GO:0034394; GO:0036309; GO:0036371; GO:0042383; GO:0043005; GO:0043034; GO:0043268; GO:0044325; GO:0045121; GO:0045211; GO:0050821; GO:0051117; GO:0051279; GO:0051597; GO:0051924; GO:0051928; GO:0055037; GO:0055117; GO:0060307; GO:0070296; GO:0070972; GO:0072659; GO:0086004; GO:0086005; GO:0086014; GO:0086015; GO:0086046; GO:0086066; GO:0086070; GO:0086091; GO:0098907; GO:0098910; GO:0140031; GO:1901018; GO:1901019; GO:1901021; GO:2001259 7115 XM_044308825.1 42 13 0 9 0 NA NA NA NA NA NA 7116 XM_029357466.2 289 0 95 72 62 NA NA NA NA NA NA 7117 XM_044306999.1 0 0 61 0 0 NA NA NA NA NA NA 7118 XM_044322156.1 603 312 222 383 587 Q9Y5T5 3.64e-59 Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.4.19.12) (Deubiquitinating enzyme 16) (Ubiquitin thioesterase 16) (Ubiquitin-processing protease UBP-M) (Ubiquitin-specific-processing protease 16) Homo sapiens (Human) cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; histone deubiquitination [GO:0016578]; histone H2A K63-linked deubiquitination [GO:0070537]; mitotic cell cycle [GO:0000278]; mitotic nuclear division [GO:0140014]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translational elongation [GO:0045901]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; regulation of cell cycle [GO:0051726]; regulation of transcription by RNA polymerase II [GO:0006357]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000278; GO:0003713; GO:0004197; GO:0004843; GO:0005634; GO:0005654; GO:0005737; GO:0006325; GO:0006357; GO:0006511; GO:0006974; GO:0008270; GO:0016578; GO:0016579; GO:0035522; GO:0042393; GO:0043130; GO:0045893; GO:0045901; GO:0045944; GO:0051289; GO:0051301; GO:0051726; GO:0070537; GO:0140014 7119 XM_044322156.1 603 312 222 383 587 Q9Y5T5 6.41e-44 Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.4.19.12) (Deubiquitinating enzyme 16) (Ubiquitin thioesterase 16) (Ubiquitin-processing protease UBP-M) (Ubiquitin-specific-processing protease 16) Homo sapiens (Human) cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; histone deubiquitination [GO:0016578]; histone H2A K63-linked deubiquitination [GO:0070537]; mitotic cell cycle [GO:0000278]; mitotic nuclear division [GO:0140014]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translational elongation [GO:0045901]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; regulation of cell cycle [GO:0051726]; regulation of transcription by RNA polymerase II [GO:0006357]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000278; GO:0003713; GO:0004197; GO:0004843; GO:0005634; GO:0005654; GO:0005737; GO:0006325; GO:0006357; GO:0006511; GO:0006974; GO:0008270; GO:0016578; GO:0016579; GO:0035522; GO:0042393; GO:0043130; GO:0045893; GO:0045901; GO:0045944; GO:0051289; GO:0051301; GO:0051726; GO:0070537; GO:0140014 7120 XM_029335597.2 8145 4813 3078 4856 5499 O75629 1.44e-43 Protein CREG1 (Cellular repressor of E1A-stimulated genes 1) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0003714; GO:0005576; GO:0005615; GO:0005667; GO:0006357; GO:0035578; GO:0070062 7121 XM_029342157.2 57 148 47 31 205 NA NA NA NA NA NA 7122 XM_044307622.1 18 0 0 16 0 NA NA NA NA NA NA 7123 XR_003825601.2 291 876 393 691 354 NA NA NA NA NA NA 7124 XM_029340963.2 2345 2084 1383 1295 1873 Q9Y2Q3 2.61e-82 Glutathione S-transferase kappa 1 (EC 2.5.1.18) (GST 13-13) (GST class-kappa) (GSTK1-1) (hGSTK1) (Glutathione S-transferase subunit 13) Homo sapiens (Human) epithelial cell differentiation [GO:0030855]; glutathione metabolic process [GO:0006749] GO:0004364; GO:0004602; GO:0005739; GO:0005759; GO:0005777; GO:0005782; GO:0005829; GO:0006749; GO:0016020; GO:0030855; GO:0070062 7125 XM_029339675.2 1051 789 513 1152 1024 Q5U4F6 3.94e-150 Cytoplasmic dynein 2 intermediate chain 2 (Dynein 2 intermediate chain 2) (WD repeat-containing protein 34) Mus musculus (Mouse) cilium assembly [GO:0060271]; intraciliary retrograde transport [GO:0035721]; intraciliary transport [GO:0042073]; microtubule-based movement [GO:0007018] GO:0005737; GO:0005813; GO:0005814; GO:0005829; GO:0005868; GO:0005929; GO:0005930; GO:0007018; GO:0030175; GO:0035721; GO:0036064; GO:0042073; GO:0045503; GO:0045504; GO:0060271; GO:0097014 7126 XM_044310130.1 0 34 69 49 33 NA NA NA NA NA NA 7127 XM_044315301.1 2589 1176 0 2621 1807 Q5F383 4.48e-112 Signal peptide peptidase-like 2B (SPP-like 2B) (SPPL2b) (EC 3.4.23.-) Gallus gallus (Chicken) membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; membrane protein proteolysis [GO:0033619]; regulation of immune response [GO:0050776] GO:0000139; GO:0005765; GO:0005886; GO:0006509; GO:0010008; GO:0030660; GO:0031293; GO:0033619; GO:0042500; GO:0042803; GO:0050776; GO:0098553; GO:0098554 7128 XM_044328735.1 87 26 45 34 258 Q96AY4 1.83e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7129 XM_044328735.1 87 26 45 34 258 Q96AY4 1.94e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7130 XM_044328735.1 87 26 45 34 258 Q96AY4 3.96e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7131 XM_044328735.1 87 26 45 34 258 Q96AY4 4.85e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7132 XM_044328735.1 87 26 45 34 258 Q96AY4 1.14e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7133 XM_044328735.1 87 26 45 34 258 Q96AY4 4e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7134 XM_029341207.2 351 268 364 510 494 P41969 4.62e-26 ETS domain-containing protein Elk-1 Mus musculus (Mouse) cell differentiation [GO:0030154]; cellular response to gamma radiation [GO:0071480]; cellular response to lipid [GO:0071396]; cellular response to testosterone stimulus [GO:0071394]; gene expression [GO:0010467]; liver development [GO:0001889]; lung development [GO:0030324]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of neuron death [GO:1901216]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; response to fibroblast growth factor [GO:0071774]; response to light stimulus [GO:0009416] GO:0000976; GO:0000978; GO:0000981; GO:0001228; GO:0001889; GO:0003682; GO:0003690; GO:0003700; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0006355; GO:0006357; GO:0009416; GO:0010467; GO:0030154; GO:0030324; GO:0030374; GO:0030425; GO:0043025; GO:0043679; GO:0045893; GO:0045944; GO:0061629; GO:0071394; GO:0071396; GO:0071480; GO:0071774; GO:1901216; GO:1990837 7135 XM_044320791.1 132 16 26 9 23 NA NA NA NA NA NA 7136 XM_044317857.1 23 0 9 7 25 NA NA NA NA NA NA 7137 XM_044321681.1 1792 1338 1006 1846 2337 Q2TCH3 0 ATP-citrate synthase (EC 2.3.3.8) (ATP-citrate (pro-S-)-lyase) (Citrate cleavage enzyme) Ovis aries (Sheep) acetyl-CoA biosynthetic process [GO:0006085]; citrate metabolic process [GO:0006101]; lipid biosynthetic process [GO:0008610]; tricarboxylic acid cycle [GO:0006099] GO:0003878; GO:0005524; GO:0005829; GO:0006085; GO:0006099; GO:0006101; GO:0008610; GO:0046872 7138 XM_029330447.2 291 207 207 249 249 NA NA NA NA NA NA 7139 XR_006397362.1 9 1 6 1 24 NA NA NA NA NA NA 7140 XM_029329752.2 1013 1237 722 22 749 Q9R0X0 5.64e-58 Mediator of RNA polymerase II transcription subunit 20 (Mediator complex subunit 20) (TRF-proximal protein homolog) Mus musculus (Mouse) positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; protein ubiquitination [GO:0016567]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA polymerase II preinitiation complex assembly [GO:0051123]; skeletal muscle cell differentiation [GO:0035914] GO:0000151; GO:0003713; GO:0005634; GO:0005654; GO:0006357; GO:0016567; GO:0016592; GO:0032968; GO:0035914; GO:0051123; GO:0060261; GO:0061630; GO:0070847 7141 XM_044313459.1 0 12 4 0 13 NA NA NA NA NA NA 7142 XM_029332120.2 2113 2239 1014 1671 2028 O14929 5.07e-129 Histone acetyltransferase type B catalytic subunit (EC 2.3.1.48) (Histone acetyltransferase 1) Homo sapiens (Human) chromosome organization [GO:0051276]; histone H4 acetylation [GO:0043967]; internal protein amino acid acetylation [GO:0006475]; nucleosome assembly [GO:0006334]; subtelomeric heterochromatin formation [GO:0031509] GO:0000781; GO:0000785; GO:0004402; GO:0005634; GO:0005654; GO:0005739; GO:0006334; GO:0006475; GO:0010485; GO:0016363; GO:0031509; GO:0032991; GO:0042393; GO:0043967; GO:0043997; GO:0051276 7143 XM_029342575.2 2483 1126 1286 1698 2001 Q6ZN57 1.95e-53 Zinc finger protein ZFP2 (Zfp-2) (Zinc finger protein 751) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 7144 XM_029342575.2 2483 1126 1286 1698 2001 Q6ZN57 6.85e-49 Zinc finger protein ZFP2 (Zfp-2) (Zinc finger protein 751) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 7145 XM_029342575.2 2483 1126 1286 1698 2001 Q6ZN57 3.54e-48 Zinc finger protein ZFP2 (Zfp-2) (Zinc finger protein 751) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 7146 XM_029342575.2 2483 1126 1286 1698 2001 Q6ZN57 5.73e-48 Zinc finger protein ZFP2 (Zfp-2) (Zinc finger protein 751) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 7147 XM_029342575.2 2483 1126 1286 1698 2001 Q6ZN57 2.65e-47 Zinc finger protein ZFP2 (Zfp-2) (Zinc finger protein 751) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 7148 XM_029342575.2 2483 1126 1286 1698 2001 Q6ZN57 1.47e-45 Zinc finger protein ZFP2 (Zfp-2) (Zinc finger protein 751) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 7149 XM_029342575.2 2483 1126 1286 1698 2001 Q6ZN57 3.53e-41 Zinc finger protein ZFP2 (Zfp-2) (Zinc finger protein 751) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 7150 XM_044319854.1 2 8 0 9 2 NA NA NA NA NA NA 7151 XM_044321449.1 232 15 511 453 65 O43900 1.28e-130 Prickle planar cell polarity protein 3 (LIM domain only protein 6) (LMO-6) (Prickle-like protein 3) (Pk3) (Triple LIM domain protein 6) Homo sapiens (Human) cell projection organization [GO:0030030] GO:0005739; GO:0005886; GO:0008270; GO:0030030 7152 XM_029347513.2 96 193 59 89 89 NA NA NA NA NA NA 7153 XM_044315335.1 42 10 12 51 26 NA NA NA NA NA NA 7154 XM_029323651.2 1588 1458 1260 1817 1506 Q6N021 2.99e-98 Methylcytosine dioxygenase TET2 (EC 1.14.11.n2) Homo sapiens (Human) 5-methylcytosine catabolic process [GO:0006211]; cell cycle [GO:0007049]; chromatin organization [GO:0006325]; DNA demethylation [GO:0080111]; leukocyte differentiation [GO:0002521]; myeloid cell differentiation [GO:0030099]; oxidative demethylation [GO:0070989]; oxidative DNA demethylation [GO:0035511]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein O-linked glycosylation [GO:0006493]; response to organic cyclic compound [GO:0014070] GO:0002521; GO:0003677; GO:0005634; GO:0006211; GO:0006325; GO:0006493; GO:0007049; GO:0008198; GO:0008270; GO:0014070; GO:0030099; GO:0035511; GO:0045944; GO:0070579; GO:0070989; GO:0080111 7155 XM_029355261.2 29 39 99 79 23 Q9EQC4 1.4e-63 Elongation of very long chain fatty acids protein 4 (EC 2.3.1.199) (3-keto acyl-CoA synthase Elovl4) (ELOVL fatty acid elongase 4) (ELOVL FA elongase 4) (Very long chain 3-ketoacyl-CoA synthase 4) (Very long chain 3-oxoacyl-CoA synthase 4) Mus musculus (Mouse) fatty acid elongation, monounsaturated fatty acid [GO:0034625]; fatty acid elongation, polyunsaturated fatty acid [GO:0034626]; fatty acid elongation, saturated fatty acid [GO:0019367]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; sphingolipid biosynthetic process [GO:0030148]; unsaturated fatty acid biosynthetic process [GO:0006636]; very long-chain fatty acid biosynthetic process [GO:0042761] GO:0005783; GO:0005789; GO:0006636; GO:0009922; GO:0019367; GO:0030148; GO:0034625; GO:0034626; GO:0035338; GO:0042761; GO:0102756 7156 XM_029328638.2 0 0 17 0 0 Q5ZKI0 9.23e-75 Calcium/calmodulin-dependent protein kinase type II delta chain (CaM kinase II subunit delta) (CaM-kinase II delta chain) (CaMK-II subunit delta) (EC 2.7.11.17) Gallus gallus (Chicken) protein phosphorylation [GO:0006468] GO:0004683; GO:0005516; GO:0005524; GO:0005737; GO:0006468; GO:0043005; GO:0106310 7157 XM_044311708.1 85 47 11 46 33 NA NA NA NA NA NA 7158 XM_029354735.2 23 68 49 73 65 A0A2B4SJA1 1.71e-119 NA NA NA NA 7159 XM_044324317.1 144 0 0 0 17 Q495W5 8.37e-110 Alpha-(1,3)-fucosyltransferase 11 (EC 2.4.1.-) (Fucosyltransferase XI) (Fuc-TXI) (FucT-XI) (Galactoside 3-L-fucosyltransferase 11) (Fucosyltransferase 11) Homo sapiens (Human) fucosylation [GO:0036065]; N-glycan fucosylation [GO:0036071]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0008417; GO:0032580; GO:0036065; GO:0036071; GO:0046920 7160 XM_044325072.1 2 2 0 0 7 NA NA NA NA NA NA 7161 XM_029346073.2 1384 1476 884 1140 915 Q8IWX5 3.88e-63 Sphingosine-1-phosphate phosphatase 2 (SPPase2) (Spp2) (hSPP2) (EC 3.1.3.-) (Sphingosine-1-phosphatase 2) Homo sapiens (Human) phospholipid dephosphorylation [GO:0046839]; regulation of type B pancreatic cell proliferation [GO:0061469]; sphingolipid biosynthetic process [GO:0030148]; sphingosine metabolic process [GO:0006670] GO:0005783; GO:0005789; GO:0006670; GO:0016020; GO:0030148; GO:0042392; GO:0046839; GO:0061469; GO:0070780 7162 XR_006397935.1 3020 2040 1706 2414 2599 Q8C428 8.74e-76 Transmembrane channel-like protein 7 Mus musculus (Mouse) NA GO:0005886; GO:0008381 7163 XM_044319926.1 597 484 379 678 751 Q68CZ1 0 Protein fantom (Nephrocystin-8) (RPGR-interacting protein 1-like protein) (RPGRIP1-like protein) Homo sapiens (Human) cerebellum development [GO:0021549]; cochlea development [GO:0090102]; corpus callosum development [GO:0022038]; determination of left/right symmetry [GO:0007368]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; establishment of planar polarity [GO:0001736]; establishment or maintenance of cell polarity [GO:0007163]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lateral ventricle development [GO:0021670]; liver development [GO:0001889]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; neural tube patterning [GO:0021532]; non-motile cilium assembly [GO:1905515]; nose development [GO:0043584]; olfactory bulb development [GO:0021772]; pericardium development [GO:0060039]; regulation of smoothened signaling pathway [GO:0008589]; retinal rod cell development [GO:0046548] GO:0001701; GO:0001736; GO:0001822; GO:0001889; GO:0005654; GO:0005737; GO:0005813; GO:0005829; GO:0005879; GO:0005886; GO:0005911; GO:0005923; GO:0005929; GO:0005930; GO:0007163; GO:0007368; GO:0008589; GO:0021532; GO:0021549; GO:0021670; GO:0021772; GO:0022038; GO:0031870; GO:0032391; GO:0035115; GO:0035116; GO:0035253; GO:0035869; GO:0036064; GO:0043584; GO:0045744; GO:0046548; GO:0060039; GO:0090102; GO:1905515 7164 XM_029332025.2 937 553 342 573 243 Q5ZKI4 0 Coiled-coil domain-containing protein 93 Gallus gallus (Chicken) Golgi to plasma membrane transport [GO:0006893]; protein transport [GO:0015031] GO:0005769; GO:0006893; GO:0015031 7165 XM_044323827.1 161 2113 739 741 505 Q15434 5.27e-77 RNA-binding motif, single-stranded-interacting protein 2 (Suppressor of CDC2 with RNA-binding motif 3) Homo sapiens (Human) RNA processing [GO:0006396] GO:0003723; GO:0003730; GO:0005634; GO:0005829; GO:0006396; GO:0008143; GO:0008266; GO:1990904 7166 XM_029337220.2 100 0 19 406 317 Q8BGX0 0 E3 ubiquitin-protein ligase TRIM23 (EC 2.3.2.27) (ADP-ribosylation factor domain-containing protein 1) (GTP-binding protein ARD-1) (RING-type E3 ubiquitin transferase TRIM23) (Tripartite motif-containing protein 23) Mus musculus (Mouse) intracellular protein transport [GO:0006886]; positive regulation of protein modification process [GO:0031401]; protein ubiquitination [GO:0016567]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0003924; GO:0004842; GO:0005525; GO:0005634; GO:0005737; GO:0005765; GO:0005886; GO:0006886; GO:0008270; GO:0016192; GO:0016567; GO:0019003; GO:0031401; GO:0042802 7167 XM_029353615.2 66 129 72 53 38 NA NA NA NA NA NA 7168 XM_029337976.2 874 1168 538 587 618 NA NA NA NA NA NA 7169 XR_003827744.2 46 0 0 8 54 Q02357 3.68e-67 Ankyrin-1 (ANK-1) (Erythrocyte ankyrin) Mus musculus (Mouse) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; erythrocyte development [GO:0048821]; inorganic cation transmembrane transport [GO:0098662]; iron ion homeostasis [GO:0055072]; porphyrin-containing compound biosynthetic process [GO:0006779]; positive regulation of organelle organization [GO:0010638]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005634; GO:0005886; GO:0006779; GO:0006888; GO:0007165; GO:0008093; GO:0009898; GO:0010638; GO:0014731; GO:0016020; GO:0016529; GO:0019899; GO:0019903; GO:0030018; GO:0030507; GO:0030673; GO:0030863; GO:0031430; GO:0031672; GO:0042383; GO:0043005; GO:0044325; GO:0045211; GO:0048821; GO:0051117; GO:0055072; GO:0072659; GO:0098662 7170 XR_003827744.2 46 0 0 8 54 Q02357 4.13e-59 Ankyrin-1 (ANK-1) (Erythrocyte ankyrin) Mus musculus (Mouse) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; erythrocyte development [GO:0048821]; inorganic cation transmembrane transport [GO:0098662]; iron ion homeostasis [GO:0055072]; porphyrin-containing compound biosynthetic process [GO:0006779]; positive regulation of organelle organization [GO:0010638]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005634; GO:0005886; GO:0006779; GO:0006888; GO:0007165; GO:0008093; GO:0009898; GO:0010638; GO:0014731; GO:0016020; GO:0016529; GO:0019899; GO:0019903; GO:0030018; GO:0030507; GO:0030673; GO:0030863; GO:0031430; GO:0031672; GO:0042383; GO:0043005; GO:0044325; GO:0045211; GO:0048821; GO:0051117; GO:0055072; GO:0072659; GO:0098662 7171 XR_003827744.2 46 0 0 8 54 Q02357 2.54e-46 Ankyrin-1 (ANK-1) (Erythrocyte ankyrin) Mus musculus (Mouse) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; erythrocyte development [GO:0048821]; inorganic cation transmembrane transport [GO:0098662]; iron ion homeostasis [GO:0055072]; porphyrin-containing compound biosynthetic process [GO:0006779]; positive regulation of organelle organization [GO:0010638]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005634; GO:0005886; GO:0006779; GO:0006888; GO:0007165; GO:0008093; GO:0009898; GO:0010638; GO:0014731; GO:0016020; GO:0016529; GO:0019899; GO:0019903; GO:0030018; GO:0030507; GO:0030673; GO:0030863; GO:0031430; GO:0031672; GO:0042383; GO:0043005; GO:0044325; GO:0045211; GO:0048821; GO:0051117; GO:0055072; GO:0072659; GO:0098662 7172 XR_003827744.2 46 0 0 8 54 Q02357 1.26e-44 Ankyrin-1 (ANK-1) (Erythrocyte ankyrin) Mus musculus (Mouse) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; erythrocyte development [GO:0048821]; inorganic cation transmembrane transport [GO:0098662]; iron ion homeostasis [GO:0055072]; porphyrin-containing compound biosynthetic process [GO:0006779]; positive regulation of organelle organization [GO:0010638]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005634; GO:0005886; GO:0006779; GO:0006888; GO:0007165; GO:0008093; GO:0009898; GO:0010638; GO:0014731; GO:0016020; GO:0016529; GO:0019899; GO:0019903; GO:0030018; GO:0030507; GO:0030673; GO:0030863; GO:0031430; GO:0031672; GO:0042383; GO:0043005; GO:0044325; GO:0045211; GO:0048821; GO:0051117; GO:0055072; GO:0072659; GO:0098662 7173 XR_003827744.2 46 0 0 8 54 Q02357 6.33e-23 Ankyrin-1 (ANK-1) (Erythrocyte ankyrin) Mus musculus (Mouse) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; erythrocyte development [GO:0048821]; inorganic cation transmembrane transport [GO:0098662]; iron ion homeostasis [GO:0055072]; porphyrin-containing compound biosynthetic process [GO:0006779]; positive regulation of organelle organization [GO:0010638]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005634; GO:0005886; GO:0006779; GO:0006888; GO:0007165; GO:0008093; GO:0009898; GO:0010638; GO:0014731; GO:0016020; GO:0016529; GO:0019899; GO:0019903; GO:0030018; GO:0030507; GO:0030673; GO:0030863; GO:0031430; GO:0031672; GO:0042383; GO:0043005; GO:0044325; GO:0045211; GO:0048821; GO:0051117; GO:0055072; GO:0072659; GO:0098662 7174 XM_044323154.1 12 0 0 15 22 NA NA NA NA NA NA 7175 XM_029341188.2 8623 8080 4548 6352 2220 Q60HC7 0 Transketolase (TK) (EC 2.2.1.1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0004802; GO:0046872 7176 XM_044312950.1 76 9 83 8 10 NA NA NA NA NA NA 7177 XM_044322842.1 26 0 0 0 4 NA NA NA NA NA NA 7178 XM_044321051.1 26 41 42 4 112 NA NA NA NA NA NA 7179 XM_044320863.1 1 6 9 19 3 NA NA NA NA NA NA 7180 XM_044314117.1 25 26 3 32 3 NA NA NA NA NA NA 7181 XM_044315997.1 68 1 6 9 27 NA NA NA NA NA NA 7182 XM_044313517.1 75 11 66 87 187 Q60HG7 3.89e-34 Cystathionine gamma-lyase (CGL) (CSE) (EC 4.4.1.1) (Cysteine desulfhydrase) (Cysteine-protein sulfhydrase) (Gamma-cystathionase) (Homocysteine desulfhydrase) (EC 4.4.1.2) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; lipid metabolic process [GO:0006629]; negative regulation of apoptotic process [GO:0043066]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein sulfhydration [GO:0044524]; protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine [GO:0018272]; transsulfuration [GO:0019346] GO:0004123; GO:0005516; GO:0005737; GO:0006629; GO:0018272; GO:0019344; GO:0019346; GO:0030170; GO:0043066; GO:0043123; GO:0044524; GO:0044540; GO:0047982; GO:0051092; GO:0070814; GO:0080146; GO:0098606 7183 XR_006392981.1 41 2 25 5 151 NA NA NA NA NA NA 7184 XM_044317569.1 80 62 44 32 29 NA NA NA NA NA NA 7185 XM_044308279.1 5181 5202 1986 4480 2729 O96952 6.58e-30 Thioredoxin (Trx) Geodia cydonium (Sponge) NA GO:0005737; GO:0015035 7186 XM_029327919.2 6 0 8 0 0 B0BN95 1.3e-34 Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease) Rattus norvegicus (Rat) NA GO:0004518; GO:0005634; GO:0005737; GO:0046872 7187 XM_044326135.1 0 0 0 3 26 NA NA NA NA NA NA 7188 XM_044307018.1 6 0 8 8 9 NA NA NA NA NA NA 7189 XM_044308611.1 201 105 103 109 427 NA NA NA NA NA NA 7190 XM_029334550.2 500 365 286 650 825 Q9H2Y7 2.07e-86 Zinc finger protein 106 (Zfp-106) (Zinc finger protein 474) Homo sapiens (Human) insulin receptor signaling pathway [GO:0008286] GO:0003723; GO:0005730; GO:0005829; GO:0008286; GO:0016020; GO:0016607; GO:0017124; GO:0046872 7191 XM_029334479.2 36 87 33 19 65 Q3U9N9 5.04e-52 Monocarboxylate transporter 10 (MCT 10) (Aromatic amino acid transporter 1) (Solute carrier family 16 member 10) (T-type amino acid transporter 1) Mus musculus (Mouse) aromatic amino acid transport [GO:0015801]; thyroid hormone generation [GO:0006590]; thyroid hormone transport [GO:0070327]; thyroid-stimulating hormone secretion [GO:0070460] GO:0005302; GO:0005886; GO:0006590; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0030054; GO:0043231; GO:0070327; GO:0070460 7192 XM_044311158.1 207 4 61 12 157 NA NA NA NA NA NA 7193 XM_044313246.1 0 31 0 193 58 NA NA NA NA NA NA 7194 XR_006392769.1 452 1333 290 129 516 NA NA NA NA NA NA 7195 XM_044320606.1 188 0 294 0 193 NA NA NA NA NA NA 7196 XM_029355802.2 156 18 49 114 114 NA NA NA NA NA NA 7197 XM_029349167.2 0 0 89 24 30 Q9CPV7 1.12e-97 Palmitoyltransferase ZDHHC6 (EC 2.3.1.225) (Stearoyltransferase ZDHHC6) (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 6) (DHHC-6) Mus musculus (Mouse) peptidyl-L-cysteine S-palmitoylation [GO:0018230]; positive regulation of mitochondrial fusion [GO:0010636]; protein palmitoylation [GO:0018345]; protein stearoylation [GO:0140438]; protein targeting to membrane [GO:0006612] GO:0005783; GO:0005789; GO:0005794; GO:0006612; GO:0010636; GO:0016409; GO:0018230; GO:0018345; GO:0019706; GO:0140438; GO:0140439 7198 XR_006397222.1 0 0 10 0 135 NA NA NA NA NA NA 7199 XR_006395893.1 867 207 187 410 276 Q6ZW61 4.02e-23 Bardet-Biedl syndrome 12 protein Homo sapiens (Human) chaperone-mediated protein complex assembly [GO:0051131]; eating behavior [GO:0042755]; fat cell differentiation [GO:0045444]; intraciliary transport [GO:0042073]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of stem cell differentiation [GO:2000737]; photoreceptor cell maintenance [GO:0045494]; stem cell differentiation [GO:0048863] GO:0005524; GO:0005929; GO:0042073; GO:0042755; GO:0045444; GO:0045494; GO:0045599; GO:0048863; GO:0051131; GO:2000737 7200 XM_029333816.2 42 3 20 122 139 P97363 0 Serine palmitoyltransferase 2 (EC 2.3.1.50) (Long chain base biosynthesis protein 2) (LCB 2) (Long chain base biosynthesis protein 2a) (LCB2a) (Serine-palmitoyl-CoA transferase 2) (SPT 2) Mus musculus (Mouse) adipose tissue development [GO:0060612]; ceramide biosynthetic process [GO:0046513]; lipophagy [GO:0061724]; positive regulation of lipophagy [GO:1904504]; sphinganine biosynthetic process [GO:0046511]; sphingolipid biosynthetic process [GO:0030148]; sphingomyelin biosynthetic process [GO:0006686]; sphingosine biosynthetic process [GO:0046512] GO:0004758; GO:0005739; GO:0005789; GO:0006686; GO:0017059; GO:0030148; GO:0030170; GO:0046511; GO:0046512; GO:0046513; GO:0060612; GO:0061724; GO:1904504 7201 XM_029346554.2 138 89 67 59 121 Q4QR88 8.82e-31 TIMELESS-interacting protein Rattus norvegicus (Rat) cell cycle phase transition [GO:0044770]; cell division [GO:0051301]; DNA damage checkpoint signaling [GO:0000077]; DNA replication checkpoint signaling [GO:0000076]; mitotic intra-S DNA damage checkpoint signaling [GO:0031573]; positive regulation of cell population proliferation [GO:0008284]; replication fork arrest [GO:0043111]; replication fork protection [GO:0048478]; response to UV [GO:0009411] GO:0000076; GO:0000077; GO:0000785; GO:0003677; GO:0005634; GO:0005737; GO:0008284; GO:0009411; GO:0031298; GO:0031573; GO:0043111; GO:0044770; GO:0048478; GO:0051301 7202 XM_029330245.2 34894 37413 30017 40649 51759 NA NA NA NA NA NA 7203 XM_029333767.2 338 342 300 199 313 Q9Y2I1 1.8e-59 Nischarin (Imidazoline receptor 1) (I-1) (IR1) (Imidazoline receptor antisera-selected protein) (hIRAS) (Imidazoline-1 receptor) (I1R) (Imidazoline-1 receptor candidate protein) (I-1 receptor candidate protein) (I1R candidate protein) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; apoptotic process [GO:0006915]; negative regulation of cell migration [GO:0030336]; Rac protein signal transduction [GO:0016601] GO:0005178; GO:0005654; GO:0005737; GO:0005769; GO:0005829; GO:0005886; GO:0006915; GO:0015630; GO:0016020; GO:0016601; GO:0019901; GO:0030036; GO:0030336; GO:0035091; GO:0042802; GO:0043231; GO:0045171; GO:0055037 7204 XM_044322143.1 427 78 141 286 78 A7T1N0 0 Transient receptor potential cation channel subfamily M member-like 2 (nvTRPM2) Nematostella vectensis (Starlet sea anemone) calcium ion transmembrane transport [GO:0070588]; cation transmembrane transport [GO:0098655]; sodium ion transmembrane transport [GO:0035725] GO:0005261; GO:0005886; GO:0015280; GO:0035725; GO:0046872; GO:0047631; GO:0070588; GO:0098655; GO:0099604 7205 XR_006394582.1 153 146 165 174 105 NA NA NA NA NA NA 7206 XR_006393936.1 58161 126114 250356 112258 112866 NA NA NA NA NA NA 7207 XM_044315218.1 145 144 161 293 333 Q9VJE5 1.49e-43 Restin homolog (Cytoplasmic linker protein 190) (Microtubule-binding protein 190) (d-CLIP-190) Drosophila melanogaster (Fruit fly) cellularization [GO:0007349]; cytoplasmic microtubule organization [GO:0031122] GO:0000776; GO:0003779; GO:0005634; GO:0005737; GO:0005794; GO:0005875; GO:0005876; GO:0007349; GO:0008017; GO:0030424; GO:0031122; GO:0035371; GO:0044295; GO:0045169; GO:0051010; GO:0070854 7208 XM_029357908.2 46 6 63 24 120 NA NA NA NA NA NA 7209 XM_029350767.2 0 15 0 12 9 NA NA NA NA NA NA 7210 XM_029339548.2 747 765 516 844 926 NA NA NA NA NA NA 7211 XM_029341988.2 595 478 390 2254 797 P43141 9.38e-32 Beta-4C adrenergic receptor (Beta-4C adrenoreceptor) (Beta-4C adrenoceptor) Meleagris gallopavo (Wild turkey) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; positive regulation of heart contraction [GO:0045823] GO:0004940; GO:0005886; GO:0007189; GO:0045823 7212 XM_029343642.2 118 55 10 63 71 NA NA NA NA NA NA 7213 XM_044325004.1 142 54 36 61 58 Q80XJ3 1.36e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 7214 XM_044325004.1 142 54 36 61 58 Q80XJ3 3.32e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 7215 XM_044325004.1 142 54 36 61 58 Q80XJ3 7.89e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 7216 XM_044325004.1 142 54 36 61 58 Q80XJ3 2e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 7217 XM_044325004.1 142 54 36 61 58 Q80XJ3 2.09e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 7218 XM_044325004.1 142 54 36 61 58 Q80XJ3 8.66e-37 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 7219 XM_044325004.1 142 54 36 61 58 Q80XJ3 2.49e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 7220 XM_044325004.1 142 54 36 61 58 Q80XJ3 1.48e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 7221 XM_044325004.1 142 54 36 61 58 Q80XJ3 8.22e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 7222 XM_044325004.1 142 54 36 61 58 Q80XJ3 4.39e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 7223 XM_044325004.1 142 54 36 61 58 Q80XJ3 1.65e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 7224 XM_044325004.1 142 54 36 61 58 Q80XJ3 1.35e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 7225 XM_044309589.1 28 24 0 0 5 NA NA NA NA NA NA 7226 XM_044314611.1 19 24 20 25 55 NA NA NA NA NA NA 7227 XR_006395836.1 296 268 157 1021 396 NA NA NA NA NA NA 7228 XM_044315388.1 6 1 25 4 107 B8VIU6 1.88e-35 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 7229 XR_006394700.1 232 98 130 89 421 NA NA NA NA NA NA 7230 XM_044319910.1 60 5 34 12 162 NA NA NA NA NA NA 7231 XM_044313660.1 0 0 13 0 0 NA NA NA NA NA NA 7232 XM_044328010.1 145 0 31 23 283 B2RS91 1.48e-132 RNA polymerase I-specific transcription initiation factor RRN3 Mus musculus (Mouse) cytoplasm organization [GO:0007028]; DNA-templated transcription initiation [GO:0006352]; fibroblast proliferation [GO:0048144]; homeostasis of number of cells [GO:0048872]; in utero embryonic development [GO:0001701]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902254]; nucleolus organization [GO:0007000]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of neuron projection development [GO:0010976]; regulation of DNA-templated transcription initiation [GO:2000142]; ribosome biogenesis [GO:0042254]; transcription initiation at RNA polymerase I promoter [GO:0006361] GO:0001042; GO:0001164; GO:0001181; GO:0001701; GO:0005634; GO:0005730; GO:0006352; GO:0006361; GO:0007000; GO:0007028; GO:0010976; GO:0042254; GO:0045893; GO:0048144; GO:0048872; GO:0070063; GO:0072332; GO:1902254; GO:2000142 7233 XR_003825031.2 783 581 597 503 484 NA NA NA NA NA NA 7234 XR_006392814.1 43 40 111 102 172 NA NA NA NA NA NA 7235 XM_029341164.2 14 10 20 10 19 P24046 2.01e-71 Gamma-aminobutyric acid receptor subunit rho-1 (GABA(A) receptor subunit rho-1) (GABA(C) receptor) Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid signaling pathway [GO:0007214]; ion transmembrane transport [GO:0034220]; modulation of chemical synaptic transmission [GO:0050804]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165] GO:0004890; GO:0005231; GO:0005254; GO:0005886; GO:0007165; GO:0007214; GO:0007268; GO:0019904; GO:0030594; GO:0034220; GO:0034707; GO:0042391; GO:0042734; GO:0042802; GO:0043005; GO:0044877; GO:0045202; GO:0045211; GO:0050804; GO:0050877; GO:0098978; GO:0098982; GO:0099507; GO:1902476; GO:1902711; GO:1904315 7236 XM_029338117.2 10767 15784 25176 7296 7917 P57093 3.25e-121 Phytanoyl-CoA dioxygenase, peroxisomal (EC 1.14.11.18) (Phytanic acid oxidase) (Phytanoyl-CoA alpha-hydroxylase) (PhyH) Rattus norvegicus (Rat) 2-oxobutyrate catabolic process [GO:0019606]; 2-oxoglutarate metabolic process [GO:0006103]; fatty acid alpha-oxidation [GO:0001561]; isoprenoid metabolic process [GO:0006720]; methyl-branched fatty acid metabolic process [GO:0097089] GO:0001561; GO:0003824; GO:0005739; GO:0005777; GO:0006103; GO:0006720; GO:0008198; GO:0019606; GO:0031406; GO:0031418; GO:0048244; GO:0097089; GO:0097731 7237 XM_044318255.1 51 28 31 47 27 NA NA NA NA NA NA 7238 XM_044327277.1 0 0 2 0 21 NA NA NA NA NA NA 7239 XM_029352053.2 520 650 273 539 123 NA NA NA NA NA NA 7240 XM_029331154.2 757 1563 527 1383 508 NA NA NA NA NA NA 7241 XM_029341922.2 127 150 74 61 156 P97677 1.32e-83 Delta-like protein 1 (Drosophila Delta homolog 1) (Delta1) Rattus norvegicus (Rat) astrocyte development [GO:0014002]; auditory receptor cell fate commitment [GO:0009912]; cell fate determination [GO:0001709]; cell-cell signaling [GO:0007267]; cerebellar molecular layer formation [GO:0021688]; cerebellar Purkinje cell layer structural organization [GO:0021693]; clathrin-dependent endocytosis [GO:0072583]; compartment pattern specification [GO:0007386]; determination of left/right symmetry [GO:0007368]; endothelial tip cell fate specification [GO:0097102]; energy homeostasis [GO:0097009]; heart looping [GO:0001947]; inhibition of neuroepithelial cell differentiation [GO:0002085]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear development [GO:0048839]; lateral inhibition [GO:0046331]; left/right axis specification [GO:0070986]; loop of Henle development [GO:0072070]; marginal zone B cell differentiation [GO:0002315]; myeloid cell differentiation [GO:0030099]; negative regulation of cardiac muscle cell differentiation [GO:2000726]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal cell differentiation [GO:0045605]; negative regulation of epithelial cell differentiation [GO:0030857]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of inner ear auditory receptor cell differentiation [GO:0045608]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of Notch signaling pathway [GO:0045746]; nephron development [GO:0072006]; nervous system development [GO:0007399]; neuroepithelial cell differentiation [GO:0060563]; neuron differentiation [GO:0030182]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; Notch signaling pathway involved in arterial endothelial cell fate commitment [GO:0060853]; organ growth [GO:0035265]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endocytosis [GO:0045807]; positive regulation of gene expression [GO:0010628]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of skeletal muscle tissue growth [GO:0048633]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proximal tubule development [GO:0072014]; proximal/distal pattern formation [GO:0009954]; regulation of blood pressure [GO:0008217]; regulation of cell adhesion [GO:0030155]; regulation of cell division [GO:0051302]; regulation of growth [GO:0040008]; regulation of neurogenesis [GO:0050767]; regulation of skeletal muscle tissue growth [GO:0048631]; regulation of somitogenesis [GO:0014807]; regulation of vascular endothelial growth factor signaling pathway [GO:1900746]; retina development in camera-type eye [GO:0060041]; retina morphogenesis in camera-type eye [GO:0060042]; skeletal muscle tissue growth [GO:0048630]; skin epidermis development [GO:0098773]; somite specification [GO:0001757]; somitogenesis [GO:0001756]; spinal cord development [GO:0021510]; type B pancreatic cell development [GO:0003323] GO:0001709; GO:0001756; GO:0001757; GO:0001947; GO:0002085; GO:0002315; GO:0003323; GO:0005112; GO:0005509; GO:0005886; GO:0005912; GO:0007219; GO:0007267; GO:0007368; GO:0007386; GO:0007399; GO:0008217; GO:0008284; GO:0008285; GO:0009912; GO:0009954; GO:0010628; GO:0014002; GO:0014807; GO:0016324; GO:0021510; GO:0021688; GO:0021693; GO:0030099; GO:0030155; GO:0030182; GO:0030857; GO:0030957; GO:0031410; GO:0032693; GO:0034351; GO:0035265; GO:0040008; GO:0042491; GO:0045121; GO:0045596; GO:0045605; GO:0045608; GO:0045638; GO:0045662; GO:0045665; GO:0045746; GO:0045747; GO:0045807; GO:0045944; GO:0046331; GO:0048018; GO:0048630; GO:0048631; GO:0048633; GO:0048665; GO:0048839; GO:0050767; GO:0051302; GO:0060041; GO:0060042; GO:0060563; GO:0060853; GO:0070986; GO:0072006; GO:0072014; GO:0072070; GO:0072583; GO:0097009; GO:0097102; GO:0097110; GO:0097150; GO:0098773; GO:1900746; GO:1903672; GO:2000726 7242 XM_044316908.1 0 1 0 0 10 NA NA NA NA NA NA 7243 XM_044316877.1 8 9 17 3 30 NA NA NA NA NA NA 7244 XM_044314544.1 1143 790 428 1066 482 NA NA NA NA NA NA 7245 XR_006397804.1 159 120 12 2 54 NA NA NA NA NA NA 7246 XM_044313589.1 273 520 210 399 372 NA NA NA NA NA NA 7247 XM_029356592.2 50 67 36 19 10 NA NA NA NA NA NA 7248 XM_044312369.1 2 0 17 0 168 Q9VBW3 8.01e-64 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 7249 XM_044317301.1 1516 2152 1261 1907 2091 Q9NZJ5 4.85e-84 Eukaryotic translation initiation factor 2-alpha kinase 3 (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase) (HsPEK) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; calcium-mediated signaling [GO:0019722]; cellular response to amino acid starvation [GO:0034198]; cellular response to cold [GO:0070417]; cellular response to glucose starvation [GO:0042149]; chondrocyte development [GO:0002063]; eiF2alpha phosphorylation in response to endoplasmic reticulum stress [GO:0036492]; endocrine pancreas development [GO:0031018]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; insulin-like growth factor receptor signaling pathway [GO:0048009]; negative regulation of myelination [GO:0031642]; negative regulation of translation [GO:0017148]; negative regulation of translation in response to stress [GO:0032055]; negative regulation of translational initiation in response to stress [GO:0032057]; ossification [GO:0001503]; peptidyl-serine phosphorylation [GO:0018105]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of vascular endothelial growth factor production [GO:0010575]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation [GO:0060734]; regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902235]; regulation of translational initiation by eIF2 alpha phosphorylation [GO:0010998]; response to endoplasmic reticulum stress [GO:0034976]; response to manganese-induced endoplasmic reticulum stress [GO:1990737]; skeletal system development [GO:0001501] GO:0001501; GO:0001503; GO:0001525; GO:0002063; GO:0004672; GO:0004674; GO:0004694; GO:0005524; GO:0005737; GO:0005783; GO:0005789; GO:0005829; GO:0006468; GO:0006919; GO:0006983; GO:0007029; GO:0010575; GO:0010628; GO:0010998; GO:0016020; GO:0017148; GO:0018105; GO:0019722; GO:0019899; GO:0019903; GO:0030282; GO:0030968; GO:0031018; GO:0031642; GO:0032055; GO:0032057; GO:0034198; GO:0034976; GO:0036492; GO:0036499; GO:0042149; GO:0042802; GO:0045943; GO:0046777; GO:0048009; GO:0048471; GO:0051879; GO:0060734; GO:0070417; GO:0106310; GO:1900182; GO:1902235; GO:1990737 7250 XM_044317301.1 1516 2152 1261 1907 2091 Q9NZJ5 1.1e-54 Eukaryotic translation initiation factor 2-alpha kinase 3 (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase) (HsPEK) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; calcium-mediated signaling [GO:0019722]; cellular response to amino acid starvation [GO:0034198]; cellular response to cold [GO:0070417]; cellular response to glucose starvation [GO:0042149]; chondrocyte development [GO:0002063]; eiF2alpha phosphorylation in response to endoplasmic reticulum stress [GO:0036492]; endocrine pancreas development [GO:0031018]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; insulin-like growth factor receptor signaling pathway [GO:0048009]; negative regulation of myelination [GO:0031642]; negative regulation of translation [GO:0017148]; negative regulation of translation in response to stress [GO:0032055]; negative regulation of translational initiation in response to stress [GO:0032057]; ossification [GO:0001503]; peptidyl-serine phosphorylation [GO:0018105]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of vascular endothelial growth factor production [GO:0010575]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation [GO:0060734]; regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902235]; regulation of translational initiation by eIF2 alpha phosphorylation [GO:0010998]; response to endoplasmic reticulum stress [GO:0034976]; response to manganese-induced endoplasmic reticulum stress [GO:1990737]; skeletal system development [GO:0001501] GO:0001501; GO:0001503; GO:0001525; GO:0002063; GO:0004672; GO:0004674; GO:0004694; GO:0005524; GO:0005737; GO:0005783; GO:0005789; GO:0005829; GO:0006468; GO:0006919; GO:0006983; GO:0007029; GO:0010575; GO:0010628; GO:0010998; GO:0016020; GO:0017148; GO:0018105; GO:0019722; GO:0019899; GO:0019903; GO:0030282; GO:0030968; GO:0031018; GO:0031642; GO:0032055; GO:0032057; GO:0034198; GO:0034976; GO:0036492; GO:0036499; GO:0042149; GO:0042802; GO:0045943; GO:0046777; GO:0048009; GO:0048471; GO:0051879; GO:0060734; GO:0070417; GO:0106310; GO:1900182; GO:1902235; GO:1990737 7251 XM_029355027.2 112 96 56 139 94 E7FAM5 1.15e-80 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 7252 XM_044315083.1 23 0 18 17 1 NA NA NA NA NA NA 7253 XM_044325549.1 19 2 0 27 0 Q80XJ3 2.37e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 7254 XM_029329720.2 606 275 153 270 483 NA NA NA NA NA NA 7255 XM_044326611.1 2312 2404 2143 3104 3812 O77775 1.62e-30 Neutrophil cytosol factor 2 (NCF-2) (67 kDa neutrophil oxidase factor) (Neutrophil NADPH oxidase factor 2) (p67-phox) Bos taurus (Bovine) phagocytosis [GO:0006909]; respiratory burst [GO:0045730]; superoxide anion generation [GO:0042554] GO:0005829; GO:0006909; GO:0016176; GO:0042554; GO:0043020; GO:0045730 7256 XR_006394911.1 18 7 8 4 17 NA NA NA NA NA NA 7257 XM_029330113.2 4793 5308 2596 4401 3645 Q5R8H3 1.2e-48 B-cell receptor-associated protein 31 (BCR-associated protein 31) (Bap31) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) apoptotic process [GO:0006915]; intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192] GO:0005789; GO:0006886; GO:0006915; GO:0016192; GO:0033116 7258 XM_029328735.2 170 38 156 45 147 Q5XGI1 1.21e-109 Kidney mitochondrial carrier protein 1 (Solute carrier family 25 member 30) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) mitochondrial transport [GO:0006839] GO:0005743; GO:0006839 7259 XM_044329304.1 58 28 111 91 124 Q3SYV5 9.65e-58 Tetraspanin-33 (Tspan-33) Bos taurus (Bovine) NA GO:0005737; GO:0005886; GO:0005912 7260 XR_003822987.2 2 0 0 7 0 NA NA NA NA NA NA 7261 XM_044313111.1 1138 1512 1392 1408 1164 Q28GH3 0 SUMO-activating enzyme subunit 2 (EC 2.3.2.-) (Ubiquitin-like 1-activating enzyme E1B) (Ubiquitin-like modifier-activating enzyme 2) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) protein sumoylation [GO:0016925] GO:0005524; GO:0005737; GO:0016740; GO:0016925; GO:0019948; GO:0031510; GO:0046872 7262 XR_006397364.1 0 14 0 24 1 NA NA NA NA NA NA 7263 XM_029348072.2 219 124 83 181 141 P17178 4.97e-89 Sterol 26-hydroxylase, mitochondrial (EC 1.14.15.15) (5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 26-hydroxylase) (Cytochrome P-450C27/25) (Cytochrome P450 27) (Sterol 27-hydroxylase) (Vitamin D(3) 25-hydroxylase) Rattus norvegicus (Rat) bile acid biosynthetic process [GO:0006699]; C21-steroid hormone biosynthetic process [GO:0006700]; calcitriol biosynthetic process from calciol [GO:0036378]; cholesterol catabolic process [GO:0006707]; cholesterol metabolic process [GO:0008203]; steroid catabolic process [GO:0006706] GO:0005506; GO:0005739; GO:0005740; GO:0005743; GO:0006699; GO:0006700; GO:0006706; GO:0006707; GO:0008123; GO:0008203; GO:0008386; GO:0020037; GO:0030343; GO:0030544; GO:0031073; GO:0036378; GO:0047103; GO:0047748; GO:0047749 7264 XM_029356076.2 904 373 336 648 775 Q8CF97 0 Deubiquitinating protein VCPIP1 (EC 3.4.19.12) (Valosin-containing protein p97/p47 complex-interacting protein 1) (Valosin-containing protein p97/p47 complex-interacting protein p135) (VCP/p47 complex-interacting 135-kDa protein) Rattus norvegicus (Rat) cellular response to DNA damage stimulus [GO:0006974]; endoplasmic reticulum membrane fusion [GO:0016320]; Golgi organization [GO:0007030]; Golgi reassembly [GO:0090168]; mitotic cell cycle [GO:0000278]; protein deubiquitination [GO:0016579]; protein K11-linked deubiquitination [GO:0035871]; protein K48-linked deubiquitination [GO:0071108]; protein ubiquitination [GO:0016567]; protein-DNA covalent cross-linking repair [GO:0106300]; regulation of protein localization to chromatin [GO:1905634] GO:0000278; GO:0004843; GO:0005634; GO:0005783; GO:0005795; GO:0006974; GO:0007030; GO:0016320; GO:0016567; GO:0016579; GO:0035871; GO:0045202; GO:0071108; GO:0090168; GO:0106300; GO:1905634 7265 XM_044316275.1 0 0 9 0 22 NA NA NA NA NA NA 7266 XM_029356839.2 0 0 0 0 8 NA NA NA NA NA NA 7267 XM_029328712.2 137 82 149 125 194 NA NA NA NA NA NA 7268 XR_003822968.2 15 3 7 0 26 NA NA NA NA NA NA 7269 XM_044312983.1 203 174 178 273 155 NA NA NA NA NA NA 7270 XM_029329937.2 208 18 0 25 84 Q9NSA2 5.69e-64 Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) Homo sapiens (Human) potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005250; GO:0005886; GO:0008076; GO:0014069; GO:0016020; GO:0034765; GO:0043025; GO:0043197; GO:0045211; GO:0046872; GO:0051260; GO:0071805 7271 XM_044312050.1 0 5 15 6 11 NA NA NA NA NA NA 7272 XM_044318637.1 0 3 0 7 0 NA NA NA NA NA NA 7273 XM_044315251.1 123 0 0 8 0 NA NA NA NA NA NA 7274 XM_044312726.1 4 3 1 3 13 NA NA NA NA NA NA 7275 XM_029337566.2 59 0 41 0 42 NA NA NA NA NA NA 7276 XM_029332183.2 1392 961 662 1292 1552 O95831 0 Apoptosis-inducing factor 1, mitochondrial (EC 1.6.99.-) (Programmed cell death protein 8) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cellular response to aldosterone [GO:1904045]; cellular response to estradiol stimulus [GO:0071392]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to nitric oxide [GO:0071732]; cellular response to oxygen-glucose deprivation [GO:0090650]; chromosome condensation [GO:0030261]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; mitochondrial respiratory chain complex assembly [GO:0033108]; mitochondrial respiratory chain complex I assembly [GO:0032981]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; positive regulation of apoptotic process [GO:0043065]; positive regulation of necroptotic process [GO:0060545]; positive regulation of neuron apoptotic process [GO:0043525]; programmed cell death [GO:0012501]; protein import into mitochondrial intermembrane space [GO:0045041]; regulation of apoptotic DNA fragmentation [GO:1902510]; response to ischemia [GO:0002931]; response to L-glutamate [GO:1902065]; response to toxic substance [GO:0009636] GO:0002931; GO:0003677; GO:0003954; GO:0005634; GO:0005737; GO:0005739; GO:0005743; GO:0005758; GO:0005829; GO:0006915; GO:0006919; GO:0009636; GO:0012501; GO:0016174; GO:0016651; GO:0030182; GO:0030261; GO:0032981; GO:0033108; GO:0043065; GO:0043525; GO:0045041; GO:0046983; GO:0048471; GO:0051402; GO:0060545; GO:0070059; GO:0070301; GO:0071392; GO:0071732; GO:0071949; GO:0072572; GO:0090650; GO:1902065; GO:1902510; GO:1904045 7277 XR_006391288.1 8 30 3 9 4 NA NA NA NA NA NA 7278 XM_029350947.2 156 176 0 56 77 NA NA NA NA NA NA 7279 XM_044326652.1 0 0 0 2 10 NA NA NA NA NA NA 7280 XM_029337555.2 1437 1568 598 871 615 Q63ZJ2 5.72e-55 Ragulator complex protein LAMTOR2-A (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 2-A) (Roadblock domain-containing protein 3) Xenopus laevis (African clawed frog) cellular response to amino acid stimulus [GO:0071230]; positive regulation of TOR signaling [GO:0032008]; protein localization [GO:0008104]; regulation of cell growth [GO:0001558] GO:0001558; GO:0005085; GO:0005765; GO:0005770; GO:0008104; GO:0031902; GO:0032008; GO:0060090; GO:0071230; GO:0071986 7281 XM_044315427.1 85 34 73 54 225 NA NA NA NA NA NA 7282 XM_029331484.2 1684 1171 821 1366 2406 Q14839 0 Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC 3.6.4.12) (ATP-dependent helicase CHD4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta) Homo sapiens (Human) chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone deacetylation [GO:0016575]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of cell fate specification [GO:0042659]; regulation of stem cell differentiation [GO:2000736]; regulation of synapse assembly [GO:0051963]; terminal button organization [GO:0072553] GO:0000122; GO:0000724; GO:0000781; GO:0000785; GO:0001221; GO:0003677; GO:0003682; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0006338; GO:0008270; GO:0010629; GO:0016020; GO:0016575; GO:0016581; GO:0016887; GO:0032991; GO:0042393; GO:0042659; GO:0042826; GO:0045892; GO:0045893; GO:0051963; GO:0061629; GO:0072553; GO:0090575; GO:0090734; GO:0140658; GO:0150048; GO:2000736 7283 XM_029331484.2 1684 1171 821 1366 2406 Q14839 3.17e-81 Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC 3.6.4.12) (ATP-dependent helicase CHD4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta) Homo sapiens (Human) chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone deacetylation [GO:0016575]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of cell fate specification [GO:0042659]; regulation of stem cell differentiation [GO:2000736]; regulation of synapse assembly [GO:0051963]; terminal button organization [GO:0072553] GO:0000122; GO:0000724; GO:0000781; GO:0000785; GO:0001221; GO:0003677; GO:0003682; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0006338; GO:0008270; GO:0010629; GO:0016020; GO:0016575; GO:0016581; GO:0016887; GO:0032991; GO:0042393; GO:0042659; GO:0042826; GO:0045892; GO:0045893; GO:0051963; GO:0061629; GO:0072553; GO:0090575; GO:0090734; GO:0140658; GO:0150048; GO:2000736 7284 XM_044319796.1 1116 811 396 382 637 Q6GL41 0 DNA replication licensing factor mcm4 (EC 3.6.4.12) (Minichromosome maintenance protein 4) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell cycle [GO:0007049]; DNA replication initiation [GO:0006270]; DNA unwinding involved in DNA replication [GO:0006268]; regulation of DNA-templated DNA replication initiation [GO:0030174]; response to yeast [GO:0001878] GO:0000785; GO:0001878; GO:0003677; GO:0003678; GO:0003682; GO:0005524; GO:0006268; GO:0006270; GO:0007049; GO:0016887; GO:0030174; GO:0042555; GO:0046872; GO:0071162 7285 XM_029335077.2 8 0 23 78 0 NA NA NA NA NA NA 7286 XM_044316286.1 77 30 8 10 111 Q80XJ3 5.05e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 7287 XM_044323939.1 151 0 0 245 228 O95263 0 High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B (HsPDE8B) (EC 3.1.4.53) (Cell proliferation-inducing gene 22 protein) Homo sapiens (Human) behavioral fear response [GO:0001662]; cAMP catabolic process [GO:0006198]; negative regulation of steroid hormone biosynthetic process [GO:0090032]; neuromuscular process controlling balance [GO:0050885]; operant conditioning [GO:0035106]; signal transduction [GO:0007165]; visual learning [GO:0008542] GO:0001662; GO:0004114; GO:0004115; GO:0005829; GO:0006198; GO:0007165; GO:0008542; GO:0035106; GO:0046872; GO:0050885; GO:0090032 7288 XM_044323323.1 0 61 0 64 52 Q6P5F6 1.78e-43 Zinc transporter ZIP10 (Solute carrier family 39 member 10) (Zrt- and Irt-like protein 10) (ZIP-10) Mus musculus (Mouse) cellular zinc ion homeostasis [GO:0006882]; negative regulation of B cell apoptotic process [GO:0002903]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of B cell receptor signaling pathway [GO:0050861]; positive regulation of protein tyrosine phosphatase activity [GO:1903615]; zinc ion import across plasma membrane [GO:0071578] GO:0002903; GO:0005385; GO:0005886; GO:0006882; GO:0030890; GO:0050861; GO:0071578; GO:1903615 7289 XM_029355937.2 2165 7163 1806 3464 3851 NA NA NA NA NA NA 7290 XM_044315584.1 78 0 12 21 48 NA NA NA NA NA NA 7291 XM_029324817.2 0 0 58 3 0 Q9NVU0 2.78e-134 DNA-directed RNA polymerase III subunit RPC5 (RNA polymerase III subunit C5) (DNA-directed RNA polymerase III 80 kDa polypeptide) Homo sapiens (Human) defense response to virus [GO:0051607]; DNA-templated transcription [GO:0006351]; innate immune response [GO:0045087] GO:0005654; GO:0005666; GO:0005829; GO:0006351; GO:0045087; GO:0051607 7292 XM_044313554.1 90 53 64 1 48 NA NA NA NA NA NA 7293 XM_044308740.1 576 258 377 885 510 NA NA NA NA NA NA 7294 XR_006393296.1 14 8 0 7 10 NA NA NA NA NA NA 7295 XM_044328264.1 2 358 50 31 36 NA NA NA NA NA NA 7296 XM_029335732.2 1538 987 666 1289 1425 Q09326 5.33e-114 Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (EC 2.4.1.143) (Beta-1,2-N-acetylglucosaminyltransferase II) (GlcNAc-T II) (GNT-II) (Mannoside acetylglucosaminyltransferase 2) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II) Rattus norvegicus (Rat) oligosaccharide biosynthetic process [GO:0009312]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279] GO:0000139; GO:0005795; GO:0006487; GO:0008455; GO:0009312; GO:0018279; GO:0030145; GO:0030246; GO:0042803 7297 XR_003823981.2 36 24 11 10 26 NA NA NA NA NA NA 7298 XM_029344032.2 4918 6636 3649 4476 5312 P38976 1.32e-83 Ras-like protein RAS2 (EC 3.6.5.2) Hydra vulgaris (Hydra) (Hydra attenuata) signal transduction [GO:0007165] GO:0003925; GO:0005525; GO:0005886; GO:0007165 7299 XR_003826785.2 1830 3544 1055 2811 1650 NA NA NA NA NA NA 7300 XM_029349686.2 861 538 333 632 549 Q96LQ0 2.55e-54 Protein phosphatase 1 regulatory subunit 36 Homo sapiens (Human) negative regulation of phosphatase activity [GO:0010923] GO:0004864; GO:0010923; GO:0019902 7301 XM_029340108.2 0 6 0 30 0 NA NA NA NA NA NA 7302 XM_044321838.1 0 9 0 0 0 NA NA NA NA NA NA 7303 XR_006391630.1 2 19 0 1 3 NA NA NA NA NA NA 7304 XM_029348838.2 0 164 261 20 493 Q9FWW9 6.97e-72 Flavin-containing monooxygenase FMO GS-OX-like 2 (EC 1.8.-.-) (Flavin-monooxygenase glucosinolate S-oxygenase-like 2) Arabidopsis thaliana (Mouse-ear cress) defense response to fungus [GO:0050832] GO:0004499; GO:0050660; GO:0050661; GO:0050832 7305 XM_044326120.1 13 3 18 30 33 NA NA NA NA NA NA 7306 XM_044324646.1 6 0 4 5 0 NA NA NA NA NA NA 7307 XR_006393322.1 101 672 537 734 688 NA NA NA NA NA NA 7308 XR_006397570.1 0 0 0 6 4 NA NA NA NA NA NA 7309 XM_029355303.2 2378 1975 949 1365 1384 Q68EJ0 1.89e-133 Cytochrome b5 reductase 4 (EC 1.6.2.2) (Flavohemoprotein b5/b5R) (b5+b5R) (N-terminal cytochrome b5 and cytochrome b5 oxidoreductase domain-containing protein) (cb5/cb5R) Rattus norvegicus (Rat) cell development [GO:0048468]; generation of precursor metabolites and energy [GO:0006091]; glucose homeostasis [GO:0042593]; insulin secretion [GO:0030073]; NADP metabolic process [GO:0006739]; reactive oxygen species metabolic process [GO:0072593]; response to antibiotic [GO:0046677]; superoxide metabolic process [GO:0006801] GO:0003958; GO:0004128; GO:0005783; GO:0006091; GO:0006739; GO:0006801; GO:0016174; GO:0016653; GO:0020037; GO:0030073; GO:0042593; GO:0046677; GO:0046872; GO:0048468; GO:0048471; GO:0050660; GO:0072593 7310 XM_044323898.1 21 1 22 17 47 Q9TV36 6.81e-22 Fibrillin-1 [Cleaved into: Asprosin] Sus scrofa (Pig) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 7311 XM_044308690.1 104 75 133 774 190 Q9Y3E5 3.63e-55 Peptidyl-tRNA hydrolase 2, mitochondrial (PTH 2) (EC 3.1.1.29) (Bcl-2 inhibitor of transcription 1) Homo sapiens (Human) apoptotic process [GO:0006915]; negative regulation of anoikis [GO:2000811]; negative regulation of gene expression [GO:0010629]; positive regulation of anoikis [GO:2000210] GO:0004045; GO:0005739; GO:0005829; GO:0006915; GO:0010629; GO:0016020; GO:2000210; GO:2000811 7312 XM_044309023.1 0 0 24 17 0 P49642 6.38e-156 DNA primase small subunit (EC 2.7.7.102) (DNA primase 49 kDa subunit) (p49) Homo sapiens (Human) DNA replication initiation [GO:0006270]; DNA replication, synthesis of RNA primer [GO:0006269] GO:0000287; GO:0003896; GO:0005654; GO:0005658; GO:0006269; GO:0006270; GO:0008270; GO:0016020; GO:0032553 7313 XM_029357449.2 25 0 127 99 28 Q80TC6 0 Zinc finger SWIM domain-containing protein 5 Mus musculus (Mouse) NA GO:0008270; GO:0031462 7314 XM_044307410.1 277 205 76 309 107 Q15434 2.89e-80 RNA-binding motif, single-stranded-interacting protein 2 (Suppressor of CDC2 with RNA-binding motif 3) Homo sapiens (Human) RNA processing [GO:0006396] GO:0003723; GO:0003730; GO:0005634; GO:0005829; GO:0006396; GO:0008143; GO:0008266; GO:1990904 7315 XM_029345755.2 90 2 0 19 0 NA NA NA NA NA NA 7316 XM_029336439.2 106 48 20 144 46 Q8NCG7 7.17e-111 Diacylglycerol lipase-beta (DAGL-beta) (DGL-beta) (EC 3.1.1.116) (KCCR13L) (PUFA-specific triacylglycerol lipase) (EC 3.1.1.3) (Sn1-specific diacylglycerol lipase beta) Homo sapiens (Human) arachidonic acid metabolic process [GO:0019369]; endocannabinoid signaling pathway [GO:0071926]; lipid catabolic process [GO:0016042]; neuroblast proliferation [GO:0007405]; neurogenesis [GO:0022008]; neurotransmitter biosynthetic process [GO:0042136]; positive regulation of triglyceride catabolic process [GO:0010898]; prostaglandin biosynthetic process [GO:0001516]; regulation of inflammatory response [GO:0050727] GO:0001516; GO:0004806; GO:0005654; GO:0005737; GO:0005765; GO:0005886; GO:0007405; GO:0010898; GO:0016042; GO:0016298; GO:0019369; GO:0022008; GO:0042136; GO:0046872; GO:0047372; GO:0050727; GO:0071926 7317 XM_029329584.2 133 739 145 169 470 A4IGL7 1.71e-98 Peroxidasin (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0005576; GO:0005604; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0031012; GO:0042744; GO:0046872; GO:0051260; GO:0070207; GO:0070831; GO:0071711; GO:0140825 7318 XM_029349779.2 44 0 0 10 0 NA NA NA NA NA NA 7319 XM_029358520.2 32 30 2 12 26 Q6PF45 1.91e-64 Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Solute carrier family 32 member 1) (Vesicular GABA transporter) (xVIAAT) Xenopus laevis (African clawed frog) beta-alanine transport [GO:0001762]; gamma-aminobutyric acid import [GO:0051939]; gamma-aminobutyric acid transport [GO:0015812]; glycine transport [GO:0015816]; neurotransmitter transport [GO:0006836] GO:0001762; GO:0006836; GO:0008021; GO:0015185; GO:0015187; GO:0015812; GO:0015816; GO:0030659; GO:0042995; GO:0051939; GO:0098793; GO:0140799; GO:0140800 7320 XM_029331435.2 396 408 0 197 0 NA NA NA NA NA NA 7321 XM_029341931.2 0 290 0 0 8 P97677 4.74e-84 Delta-like protein 1 (Drosophila Delta homolog 1) (Delta1) Rattus norvegicus (Rat) astrocyte development [GO:0014002]; auditory receptor cell fate commitment [GO:0009912]; cell fate determination [GO:0001709]; cell-cell signaling [GO:0007267]; cerebellar molecular layer formation [GO:0021688]; cerebellar Purkinje cell layer structural organization [GO:0021693]; clathrin-dependent endocytosis [GO:0072583]; compartment pattern specification [GO:0007386]; determination of left/right symmetry [GO:0007368]; endothelial tip cell fate specification [GO:0097102]; energy homeostasis [GO:0097009]; heart looping [GO:0001947]; inhibition of neuroepithelial cell differentiation [GO:0002085]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear development [GO:0048839]; lateral inhibition [GO:0046331]; left/right axis specification [GO:0070986]; loop of Henle development [GO:0072070]; marginal zone B cell differentiation [GO:0002315]; myeloid cell differentiation [GO:0030099]; negative regulation of cardiac muscle cell differentiation [GO:2000726]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal cell differentiation [GO:0045605]; negative regulation of epithelial cell differentiation [GO:0030857]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of inner ear auditory receptor cell differentiation [GO:0045608]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of Notch signaling pathway [GO:0045746]; nephron development [GO:0072006]; nervous system development [GO:0007399]; neuroepithelial cell differentiation [GO:0060563]; neuron differentiation [GO:0030182]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; Notch signaling pathway involved in arterial endothelial cell fate commitment [GO:0060853]; organ growth [GO:0035265]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endocytosis [GO:0045807]; positive regulation of gene expression [GO:0010628]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of skeletal muscle tissue growth [GO:0048633]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proximal tubule development [GO:0072014]; proximal/distal pattern formation [GO:0009954]; regulation of blood pressure [GO:0008217]; regulation of cell adhesion [GO:0030155]; regulation of cell division [GO:0051302]; regulation of growth [GO:0040008]; regulation of neurogenesis [GO:0050767]; regulation of skeletal muscle tissue growth [GO:0048631]; regulation of somitogenesis [GO:0014807]; regulation of vascular endothelial growth factor signaling pathway [GO:1900746]; retina development in camera-type eye [GO:0060041]; retina morphogenesis in camera-type eye [GO:0060042]; skeletal muscle tissue growth [GO:0048630]; skin epidermis development [GO:0098773]; somite specification [GO:0001757]; somitogenesis [GO:0001756]; spinal cord development [GO:0021510]; type B pancreatic cell development [GO:0003323] GO:0001709; GO:0001756; GO:0001757; GO:0001947; GO:0002085; GO:0002315; GO:0003323; GO:0005112; GO:0005509; GO:0005886; GO:0005912; GO:0007219; GO:0007267; GO:0007368; GO:0007386; GO:0007399; GO:0008217; GO:0008284; GO:0008285; GO:0009912; GO:0009954; GO:0010628; GO:0014002; GO:0014807; GO:0016324; GO:0021510; GO:0021688; GO:0021693; GO:0030099; GO:0030155; GO:0030182; GO:0030857; GO:0030957; GO:0031410; GO:0032693; GO:0034351; GO:0035265; GO:0040008; GO:0042491; GO:0045121; GO:0045596; GO:0045605; GO:0045608; GO:0045638; GO:0045662; GO:0045665; GO:0045746; GO:0045747; GO:0045807; GO:0045944; GO:0046331; GO:0048018; GO:0048630; GO:0048631; GO:0048633; GO:0048665; GO:0048839; GO:0050767; GO:0051302; GO:0060041; GO:0060042; GO:0060563; GO:0060853; GO:0070986; GO:0072006; GO:0072014; GO:0072070; GO:0072583; GO:0097009; GO:0097102; GO:0097110; GO:0097150; GO:0098773; GO:1900746; GO:1903672; GO:2000726 7322 XM_029332575.2 925 275 465 278 324 Q7ZVE0 4.18e-47 H/ACA ribonucleoprotein complex subunit 1 (Nucleolar protein family A member 1) (snoRNP protein GAR1) Danio rerio (Zebrafish) (Brachydanio rerio) definitive hemopoiesis [GO:0060216]; rRNA processing [GO:0006364]; snoRNA guided rRNA pseudouridine synthesis [GO:0000454]; telomere maintenance via telomerase [GO:0007004] GO:0000454; GO:0005697; GO:0006364; GO:0007004; GO:0031429; GO:0034513; GO:0060216 7323 XM_044315725.1 28 22 47 15 21 Q7LHG5 9.01e-65 Transposon Ty3-I Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-2 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p52 (IN); Integrase p49 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 7324 XM_044311602.1 0 10 6 0 0 NA NA NA NA NA NA 7325 XM_029332749.2 48 10 17 15 75 NA NA NA NA NA NA 7326 XM_044314118.1 52 47 24 43 79 P33727 4.31e-164 Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S) Felis catus (Cat) (Felis silvestris catus) colon epithelial cell migration [GO:0061580]; positive regulation of neuron projection development [GO:0010976]; regulation of epithelial cell migration [GO:0010632] GO:0003943; GO:0005764; GO:0009986; GO:0010632; GO:0010976; GO:0046872; GO:0061580 7327 XM_029357460.2 726 293 338 435 648 Q8BGV9 1.61e-113 Cysteine protease ATG4D (EC 3.4.22.-) (AUT-like 4 cysteine endopeptidase) (Autophagy-related cysteine endopeptidase 4) (Autophagin-4) (Autophagy-related protein 4 homolog D) [Cleaved into: Cysteine protease ATG4D, mitochondrial] Mus musculus (Mouse) apoptotic process [GO:0006915]; autophagy [GO:0006914]; mitophagy [GO:0000423]; protein delipidation [GO:0051697]; protein localization to phagophore assembly site [GO:0034497]; protein transport [GO:0015031]; proteolysis [GO:0006508] GO:0000423; GO:0005654; GO:0005739; GO:0005759; GO:0006508; GO:0006914; GO:0006915; GO:0008234; GO:0015031; GO:0019786; GO:0034497; GO:0051697 7328 XR_006395125.1 278 312 35 154 207 NA NA NA NA NA NA 7329 XM_029324201.2 150 98 250 539 9 NA NA NA NA NA NA 7330 XM_029357336.2 734 603 511 399 749 A7YY53 3.02e-80 Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase (EC 3.6.1.13) (EC 3.6.1.16) (EC 3.6.1.53) (ADPRibase-Mn) (CDP-choline phosphohydrolase) Bos taurus (Bovine) NA GO:0008663; GO:0030145; GO:0047631; GO:0047734 7331 XR_003822728.2 8 0 3 0 2 NA NA NA NA NA NA 7332 XM_029356267.2 1288 1745 248 226 281 Q95108 5.21e-36 Thioredoxin, mitochondrial (MTRX) (Mt-Trx) (Thioredoxin-2) Bos taurus (Bovine) cell redox homeostasis [GO:0045454] GO:0005730; GO:0005739; GO:0015035; GO:0045454 7333 XR_006397060.1 184 95 28 224 375 NA NA NA NA NA NA 7334 XR_006397947.1 24 4 43 4 52 NA NA NA NA NA NA 7335 XM_044319558.1 100 56 1 24 22 NA NA NA NA NA NA 7336 XM_044313846.1 27 21 0 28 8 NA NA NA NA NA NA 7337 XM_029356318.2 0 0 11 19 14 NA NA NA NA NA NA 7338 XM_029338663.2 3886 2188 1206 3981 4635 Q9WV92 1.49e-94 Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1) (Erythrocyte membrane protein band 4.1-like 3) [Cleaved into: Band 4.1-like protein 3, N-terminally processed] Mus musculus (Mouse) actomyosin structure organization [GO:0031032]; apoptotic process [GO:0006915]; axon development [GO:0061564]; cortical actin cytoskeleton organization [GO:0030866]; cortical cytoskeleton organization [GO:0030865]; myelin maintenance [GO:0043217]; neuron projection morphogenesis [GO:0048812]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; protein localization to plasma membrane [GO:0072659]; regulation of cell shape [GO:0008360] GO:0002175; GO:0003779; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0005911; GO:0006915; GO:0008360; GO:0014069; GO:0030054; GO:0030865; GO:0030866; GO:0030913; GO:0031032; GO:0033270; GO:0043217; GO:0044224; GO:0048812; GO:0061564; GO:0071205; GO:0072659; GO:0106006; GO:1990227 7339 XM_044319960.1 455 198 216 321 303 Q8VDS4 1.93e-101 Regulation of nuclear pre-mRNA domain-containing protein 1A (Cyclin-dependent kinase inhibitor 2B-related protein) (p15INK4B-related protein) Mus musculus (Mouse) dephosphorylation of RNA polymerase II C-terminal domain [GO:0070940]; mRNA 3'-end processing [GO:0031124] GO:0000993; GO:0005634; GO:0016591; GO:0031124; GO:0042802; GO:0070940 7340 XR_006395123.1 27 6 0 17 26 NA NA NA NA NA NA 7341 XM_029343654.2 0 0 37 0 0 NA NA NA NA NA NA 7342 XM_029323402.2 309 351 175 324 259 Q9XTR8 3.59e-25 Lipase ZK262.3 (EC 3.1.1.-) Caenorhabditis elegans lipid catabolic process [GO:0016042] GO:0005576; GO:0016042; GO:0016787 7343 XM_029341102.2 0 0 12 6 17 NA NA NA NA NA NA 7344 XR_003824268.2 148 60 45 70 46 NA NA NA NA NA NA 7345 XM_044307676.1 585 634 279 279 423 NA NA NA NA NA NA 7346 XM_044308678.1 2899 1633 1013 2601 1785 Q80U12 0 Small G protein signaling modulator 2 (RUN and TBC1 domain-containing protein 1) Mus musculus (Mouse) activation of GTPase activity [GO:0090630]; late endosome to Golgi transport [GO:0034499]; positive regulation of GTPase activity [GO:0043547] GO:0005096; GO:0005737; GO:0031267; GO:0034499; GO:0042470; GO:0043547; GO:0090630 7347 XM_029331087.2 144 194 81 0 0 Q9BXB4 0 Oxysterol-binding protein-related protein 11 (ORP-11) (OSBP-related protein 11) Homo sapiens (Human) fat cell differentiation [GO:0045444]; positive regulation of sequestering of triglyceride [GO:0010890] GO:0005654; GO:0005794; GO:0005829; GO:0010890; GO:0015248; GO:0016020; GO:0031902; GO:0032934; GO:0043231; GO:0045444 7348 XR_006392600.1 27 0 7 31 22 NA NA NA NA NA NA 7349 XM_044320748.1 4 17 36 0 21 NA NA NA NA NA NA 7350 XM_044321210.1 33 0 12 8 0 NA NA NA NA NA NA 7351 XM_044329099.1 96 28 64 20 88 NA NA NA NA NA NA 7352 XM_044310639.1 40 2 12 2 7 NA NA NA NA NA NA 7353 XM_044325676.1 40 0 5 0 28 NA NA NA NA NA NA 7354 XM_029339811.2 528 0 0 34 230 NA NA NA NA NA NA 7355 XR_006392703.1 18 88 97 28 174 NA NA NA NA NA NA 7356 XM_029343970.2 691 667 393 521 494 Q2TBN5 2.09e-49 COMM domain-containing protein 9 Bos taurus (Bovine) sodium ion transport [GO:0006814] GO:0005634; GO:0006814; GO:0031410 7357 XM_029327172.2 375 423 165 216 112 Q9NX01 4.61e-81 Thioredoxin-like protein 4B (Dim1-like protein) Homo sapiens (Human) cell cycle [GO:0007049]; mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0005654; GO:0005681; GO:0005682; GO:0005829; GO:0007049; GO:0046540 7358 XM_044326405.1 31 28 127 190 132 P30975 1.82e-25 Tachykinin-like peptides receptor 99D (Tachykinin-like receptor at 99D) (dTKR) Drosophila melanogaster (Fruit fly) detection of chemical stimulus involved in sensory perception of smell [GO:0050911]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; neuropeptide signaling pathway [GO:0007218]; olfactory behavior [GO:0042048]; positive regulation of sensory perception of pain [GO:1904058]; tachykinin receptor signaling pathway [GO:0007217] GO:0004995; GO:0005886; GO:0007186; GO:0007217; GO:0007218; GO:0008188; GO:0016020; GO:0042048; GO:0050805; GO:0050911; GO:1904058 7359 XM_029351106.2 1 0 12 20 0 NA NA NA NA NA NA 7360 XR_006395768.1 4 5 8 22 109 NA NA NA NA NA NA 7361 XM_044316851.1 67 44 37 59 42 NA NA NA NA NA NA 7362 XM_029347113.2 32 267 121 113 0 NA NA NA NA NA NA 7363 XM_044322449.1 288 194 15 23 148 NA NA NA NA NA NA 7364 XM_029345790.2 498 298 275 487 577 NA NA NA NA NA NA 7365 XM_044326178.1 0 1 21 0 0 NA NA NA NA NA NA 7366 XM_044326164.1 52 14 48 137 240 NA NA NA NA NA NA 7367 XR_006393454.1 63 291 61 0 0 NA NA NA NA NA NA 7368 XM_029351246.2 362 234 151 199 268 A8Y5U1 4.84e-48 RAB7A-interacting MON1-CCZ1 complex subunit 1 (UPF0600 protein C5orf51 homolog) Danio rerio (Zebrafish) (Brachydanio rerio) mitophagy [GO:0000423] GO:0000423; GO:0005829 7369 XM_044308306.1 40 146 39 4 41 NA NA NA NA NA NA 7370 XM_044313558.1 31 19 15 36 38 NA NA NA NA NA NA 7371 XM_044307958.1 24 1 0 0 37 NA NA NA NA NA NA 7372 XM_044318826.1 225 12 203 256 25 NA NA NA NA NA NA 7373 XM_044328924.1 13 17 0 19 0 Q90415 4.01e-58 Retinoic acid receptor RXR-alpha-B (Nuclear receptor subfamily 2 group B member 1-B) (Retinoid X receptor alpha-B) Danio rerio (Zebrafish) (Brachydanio rerio) anatomical structure development [GO:0048856]; cell differentiation [GO:0030154]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; response to retinoic acid [GO:0032526]; retinoic acid receptor signaling pathway [GO:0048384] GO:0000122; GO:0000978; GO:0003700; GO:0003707; GO:0004879; GO:0006357; GO:0008270; GO:0030154; GO:0032526; GO:0044323; GO:0045944; GO:0048384; GO:0048856; GO:0090575 7374 XM_029323410.2 1838 1448 1324 2423 2070 Q9NUQ6 7.1e-39 SPATS2-like protein (DNA polymerase-transactivated protein 6) (Stress granule and nucleolar protein) (SGNP) Homo sapiens (Human) NA GO:0003723; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0032991 7375 XM_044311113.1 33 0 1 1 29 NA NA NA NA NA NA 7376 XM_044312196.1 34 5 3 23 8 NA NA NA NA NA NA 7377 XM_044325989.1 0 1348 978 2 256 NA NA NA NA NA NA 7378 XM_029323439.2 1597 961 944 1498 1708 Q68CP4 8.18e-113 Heparan-alpha-glucosaminide N-acetyltransferase (EC 2.3.1.78) (Transmembrane protein 76) Homo sapiens (Human) heparan sulfate proteoglycan catabolic process [GO:0030200]; lysosomal transport [GO:0007041]; protein complex oligomerization [GO:0051259] GO:0005765; GO:0005886; GO:0007041; GO:0015019; GO:0016746; GO:0030200; GO:0035579; GO:0043202; GO:0051259; GO:0070821 7379 XM_044317557.1 31 61 43 26 110 Q8IN35 3.59e-24 Neuropeptide SIFamide receptor Drosophila melanogaster (Fruit fly) determination of adult lifespan [GO:0008340]; G protein-coupled receptor signaling pathway [GO:0007186]; mating behavior, sex discrimination [GO:0048047]; neuropeptide signaling pathway [GO:0007218] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0008340; GO:0008528; GO:0016020; GO:0042277; GO:0048047 7380 XM_029342375.2 216 239 548 834 446 Q63ZK1 8.81e-49 Mitochondrial intermembrane space import and assembly protein 40-B (Coiled-coil-helix-coiled-coil-helix domain-containing protein 4-B) Xenopus laevis (African clawed frog) 'de novo' post-translational protein folding [GO:0051084]; protein import into mitochondrial intermembrane space [GO:0045041]; protein maturation by protein folding [GO:0022417] GO:0005758; GO:0015035; GO:0022417; GO:0045041; GO:0051084 7381 XM_029332275.2 1013 860 283 476 593 Q7ZV00 4.46e-64 Deubiquitinase OTUD6B (EC 3.4.19.12) Danio rerio (Zebrafish) (Brachydanio rerio) protein deubiquitination [GO:0016579] GO:0004843; GO:0016579 7382 XM_044313333.1 101 3 2 346 93 A2AJ76 9.91e-33 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 7383 XM_044313333.1 101 3 2 346 93 A2AJ76 5.08e-24 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 7384 XR_006394000.1 21 11 21 15 72 NA NA NA NA NA NA 7385 XR_006395863.1 195 21 161 131 185 Q9DBC0 9.1e-165 Protein adenylyltransferase SelO, mitochondrial (EC 2.7.7.-) (EC 2.7.7.108) (Selenoprotein O) (SelO) Mus musculus (Mouse) protein adenylylation [GO:0018117] GO:0005524; GO:0005694; GO:0005739; GO:0018117; GO:0046872; GO:0070733 7386 XM_029356106.2 0 8 0 9 0 NA NA NA NA NA NA 7387 XM_044323171.1 399 289 130 325 322 Q99N87 9.22e-63 28S ribosomal protein S5, mitochondrial (MRP-S5) (S5mt) Mus musculus (Mouse) mitochondrial translation [GO:0032543]; translation [GO:0006412] GO:0003723; GO:0003735; GO:0005739; GO:0005743; GO:0005763; GO:0006412; GO:0032543 7388 XM_029357194.2 55 45 72 37 273 Q3SZD5 4.74e-25 DDB1- and CUL4-associated factor 15 Bos taurus (Bovine) immune system process [GO:0002376]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of natural killer cell activation [GO:0032814] GO:0000209; GO:0002376; GO:0016567; GO:0032814; GO:0036094; GO:0046872; GO:0080008 7389 XM_029348189.2 2029 2323 1081 1599 1689 Q6NWF4 1.15e-71 Vacuolar protein-sorting-associated protein 25 (ESCRT-II complex subunit VPS25) Danio rerio (Zebrafish) (Brachydanio rerio) anatomical structure development [GO:0048856]; protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328] GO:0000814; GO:0005198; GO:0042803; GO:0043328; GO:0048856 7390 XM_044322845.1 0 12 0 33 48 NA NA NA NA NA NA 7391 XM_029324722.2 781 677 377 813 564 Q9NYQ6 5.74e-38 Cadherin EGF LAG seven-pass G-type receptor 1 (Cadherin family member 9) (Flamingo homolog 2) (hFmi2) Homo sapiens (Human) apical protein localization [GO:0045176]; cell-cell adhesion [GO:0098609]; central nervous system development [GO:0007417]; establishment of body hair planar orientation [GO:0048105]; establishment of planar polarity [GO:0001736]; establishment of planar polarity of embryonic epithelium [GO:0042249]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lateral sprouting involved in lung morphogenesis [GO:0060490]; neural tube closure [GO:0001843]; neuron migration [GO:0001764]; orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060488]; planar dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060489]; protein localization involved in establishment of planar polarity [GO:0090251]; regulation of actin cytoskeleton organization [GO:0032956]; Rho protein signal transduction [GO:0007266]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001736; GO:0001764; GO:0001843; GO:0004930; GO:0005509; GO:0005654; GO:0005886; GO:0007156; GO:0007266; GO:0007417; GO:0016020; GO:0032956; GO:0042249; GO:0045176; GO:0048105; GO:0060071; GO:0060488; GO:0060489; GO:0060490; GO:0090251; GO:0098609 7392 XM_029349904.2 16806 9424 5153 4556 2423 Q24133 8.92e-100 DnaJ protein homolog 1 (DROJ1) Drosophila melanogaster (Fruit fly) chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of crystal cell differentiation [GO:0042691]; protein folding [GO:0006457]; protein stabilization [GO:0050821]; response to heat [GO:0009408] GO:0000122; GO:0005829; GO:0006457; GO:0009408; GO:0042691; GO:0050821; GO:0051082; GO:0051085; GO:0051087; GO:0140297 7393 XM_029323525.2 76 80 111 191 131 NA NA NA NA NA NA 7394 XR_006393068.1 41 2 25 5 151 NA NA NA NA NA NA 7395 XR_006393102.1 0 6 2 0 15 NA NA NA NA NA NA 7396 XR_006392617.1 200 31 18 194 32 NA NA NA NA NA NA 7397 XM_044313600.1 39 41 56 63 80 O00222 3.99e-146 Metabotropic glutamate receptor 8 (mGluR8) Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway [GO:0007196]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; G protein-coupled glutamate receptor signaling pathway [GO:0007216]; regulation of synaptic transmission, glutamatergic [GO:0051966]; visual perception [GO:0007601] GO:0001640; GO:0001642; GO:0004930; GO:0005886; GO:0007193; GO:0007196; GO:0007216; GO:0007601; GO:0008066; GO:0051966 7398 XM_029335488.2 653 1984 3248 3152 1638 NA NA NA NA NA NA 7399 XM_044316802.1 78 147 41 35 0 Q6ZNA5 9.72e-37 Ferric-chelate reductase 1 (EC 1.-.-.-) (Stromal cell-derived receptor 2) (SDR-2) Homo sapiens (Human) cellular iron ion homeostasis [GO:0006879] GO:0006879; GO:0016020; GO:0016722; GO:0046872 7400 XM_044308834.1 1242 1017 879 1430 680 NA NA NA NA NA NA 7401 XM_029339408.2 48 0 0 160 11 NA NA NA NA NA NA 7402 XM_044320539.1 1043 241 193 706 950 B2KI97 0 THO complex subunit 2 (Tho2) Rhinolophus ferrumequinum (Greater horseshoe bat) generation of neurons [GO:0048699]; mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; neuron development [GO:0048666]; RNA splicing [GO:0008380] GO:0000347; GO:0003723; GO:0006397; GO:0006406; GO:0008380; GO:0016607; GO:0048666; GO:0048699 7403 XM_044318703.1 0 0 0 25 0 NA NA NA NA NA NA 7404 XM_044322714.1 1181 2165 1061 842 1379 Q9WU63 6.37e-36 Heme-binding protein 2 (Protein SOUL) Mus musculus (Mouse) negative regulation of mitochondrial membrane potential [GO:0010917]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of necrotic cell death [GO:0010940] GO:0005737; GO:0005739; GO:0010917; GO:0010940; GO:0020037; GO:0035794 7405 XM_029349963.2 2034 1642 1339 3464 2601 Q9Y6W6 6.67e-64 Dual specificity protein phosphatase 10 (EC 3.1.3.16) (EC 3.1.3.48) (Mitogen-activated protein kinase phosphatase 5) (MAP kinase phosphatase 5) (MKP-5) Homo sapiens (Human) dephosphorylation [GO:0016311]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelium regeneration [GO:1905042]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of JNK cascade [GO:0046329]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; negative regulation of respiratory burst involved in inflammatory response [GO:0060266]; oligodendrocyte differentiation [GO:0048709]; peptidyl-threonine dephosphorylation [GO:0035970]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; positive regulation of regulatory T cell differentiation [GO:0045591]; regulation of adaptive immune response [GO:0002819]; regulation of brown fat cell differentiation [GO:0090335]; response to lipopolysaccharide [GO:0032496]; stress-activated MAPK cascade [GO:0051403] GO:0002819; GO:0004721; GO:0004725; GO:0005634; GO:0005654; GO:0005737; GO:0005794; GO:0005829; GO:0008330; GO:0008432; GO:0010633; GO:0016311; GO:0016607; GO:0016791; GO:0017017; GO:0017018; GO:0030336; GO:0032496; GO:0033549; GO:0035970; GO:0043409; GO:0043508; GO:0044387; GO:0045591; GO:0046329; GO:0048273; GO:0048709; GO:0048715; GO:0050680; GO:0051403; GO:0060266; GO:0070373; GO:0090335; GO:1903753; GO:1905042; GO:1990264 7406 XM_044321921.1 3078 2298 2148 2615 2819 NA NA NA NA NA NA 7407 XM_029342676.2 51 0 0 21 0 Q8TDX7 5.03e-176 Serine/threonine-protein kinase Nek7 (EC 2.7.11.1) (Never in mitosis A-related kinase 7) (NimA-related protein kinase 7) Homo sapiens (Human) cellular response to potassium ion [GO:0035865]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of NLRP3 inflammasome complex assembly [GO:1900227]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein phosphorylation [GO:0006468]; regulation of mitotic cell cycle [GO:0007346]; spindle assembly [GO:0051225] GO:0000922; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005815; GO:0005874; GO:0006468; GO:0007346; GO:0018105; GO:0032212; GO:0035865; GO:0046872; GO:0051225; GO:0051973; GO:0106310; GO:0140677; GO:1900227; GO:1904355 7408 XR_003825783.2 5 27 25 16 63 NA NA NA NA NA NA 7409 XR_006397461.1 22 10 9 21 76 NA NA NA NA NA NA 7410 XR_006396139.1 0 22 0 0 93 NA NA NA NA NA NA 7411 XM_029330998.2 171 225 135 142 81 NA NA NA NA NA NA 7412 XR_003826088.2 63 37 18 14 28 NA NA NA NA NA NA 7413 XM_029331129.2 1015 823 347 714 969 A4IH88 3.43e-73 Uncharacterized protein KIAA2013 homolog Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0016020 7414 XR_006396803.1 73 82 57 143 109 NA NA NA NA NA NA 7415 XM_044311272.1 0 142 438 602 791 F1R4Y7 7.32e-72 Centrosomal protein of 83 kDa (Cep83) (Coiled-coil domain-containing protein 41) Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; establishment of centrosome localization [GO:0051660] GO:0005737; GO:0005814; GO:0051660; GO:0060271; GO:0097539 7416 XM_029333845.2 204 23 24 147 116 NA NA NA NA NA NA 7417 XM_029357208.2 9 29 0 23 10 Q8R4G9 4.48e-49 Neuronal acetylcholine receptor subunit alpha-3 Mus musculus (Mouse) acetylcholine receptor signaling pathway [GO:0095500]; activation of transmembrane receptor protein tyrosine kinase activity [GO:0007171]; behavioral response to nicotine [GO:0035095]; chemical synaptic transmission [GO:0007268]; excitatory postsynaptic potential [GO:0060079]; ion transmembrane transport [GO:0034220]; locomotory behavior [GO:0007626]; membrane depolarization [GO:0051899]; nervous system development [GO:0007399]; nervous system process [GO:0050877]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of acetylcholine secretion, neurotransmission [GO:0014056]; regulation of dendrite morphogenesis [GO:0048814]; regulation of membrane potential [GO:0042391]; regulation of muscle contraction [GO:0006937]; regulation of smooth muscle contraction [GO:0006940]; response to acetylcholine [GO:1905144]; response to xenobiotic stimulus [GO:0009410]; signal transduction [GO:0007165]; synaptic transmission involved in micturition [GO:0060084]; synaptic transmission, cholinergic [GO:0007271] GO:0005231; GO:0005886; GO:0005892; GO:0006937; GO:0006940; GO:0007165; GO:0007171; GO:0007268; GO:0007271; GO:0007399; GO:0007626; GO:0009410; GO:0014056; GO:0014069; GO:0015464; GO:0016020; GO:0016607; GO:0022848; GO:0030425; GO:0030594; GO:0032991; GO:0034220; GO:0035095; GO:0042166; GO:0042391; GO:0043005; GO:0043025; GO:0044853; GO:0044877; GO:0045202; GO:0045211; GO:0048814; GO:0050877; GO:0051899; GO:0060079; GO:0060084; GO:0095500; GO:0098691; GO:0098793; GO:0098981; GO:0099171; GO:0099634; GO:1901363; GO:1904315; GO:1905144 7418 XM_044307673.1 99 170 18 123 93 NA NA NA NA NA NA 7419 XR_006393075.1 41 2 25 5 151 NA NA NA NA NA NA 7420 XM_044327213.1 9 14 6 7 8 NA NA NA NA NA NA 7421 XR_006391783.1 0 0 0 13 0 NA NA NA NA NA NA 7422 XM_044309082.1 10 1 0 23 13 Q96AY4 5.38e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7423 XM_044309082.1 10 1 0 23 13 Q96AY4 4.67e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7424 XM_044309082.1 10 1 0 23 13 Q96AY4 6.94e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7425 XM_044309082.1 10 1 0 23 13 Q96AY4 1.52e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7426 XM_044309082.1 10 1 0 23 13 Q96AY4 8.09e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7427 XM_029324597.2 898 231 1060 1288 758 NA NA NA NA NA NA 7428 XM_029331119.2 6 0 0 29 0 Q9H8H2 4.2e-146 Probable ATP-dependent RNA helicase DDX31 (EC 3.6.4.13) (DEAD box protein 31) (Helicain) Homo sapiens (Human) ribosome biogenesis [GO:0042254] GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005730; GO:0005794; GO:0016887; GO:0042254; GO:0043231 7429 XR_006393697.1 23 3 31 49 24 NA NA NA NA NA NA 7430 XM_029352595.2 0 17 0 0 0 Q8N8E3 0 Centrosomal protein of 112 kDa (Cep112) (Coiled-coil domain-containing protein 46) Homo sapiens (Human) receptor localization to synapse [GO:0097120] GO:0005737; GO:0005813; GO:0005886; GO:0060077; GO:0097120 7431 XR_006397766.1 108 204 16 236 81 NA NA NA NA NA NA 7432 XM_029339762.2 0 0 36 54 68 Q08CY9 1.87e-156 EGF domain-specific O-linked N-acetylglucosamine transferase (EC 2.4.1.255) (Extracellular O-linked N-acetylglucosamine transferase) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) protein O-linked glycosylation [GO:0006493] GO:0005788; GO:0006493; GO:0097363 7433 XM_029342324.2 152 162 236 257 179 Q9HC36 1.29e-46 rRNA methyltransferase 3, mitochondrial (EC 2.1.1.-) (16S rRNA (guanosine(1370)-2'-O)-methyltransferase) (16S rRNA [Gm1370] 2'-O-methyltransferase) (RNA methyltransferase-like protein 1) Homo sapiens (Human) rRNA 2'-O-methylation [GO:0000451] GO:0000451; GO:0003723; GO:0005739; GO:0005759; GO:0042802; GO:0070039 7434 XM_044323390.1 8 9 21 16 13 NA NA NA NA NA NA 7435 XM_044312875.1 56 38 42 88 108 NA NA NA NA NA NA 7436 XR_006392367.1 50 0 0 2 301 NA NA NA NA NA NA 7437 XM_029333619.2 19 0 0 0 0 P16066 1.05e-66 Atrial natriuretic peptide receptor 1 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type A) (ANP-A) (ANPR-A) (NPR-A) (Guanylate cyclase A) (GC-A) Homo sapiens (Human) blood vessel diameter maintenance [GO:0097746]; body fluid secretion [GO:0007589]; cell surface receptor signaling pathway [GO:0007166]; cGMP biosynthetic process [GO:0006182]; cGMP-mediated signaling [GO:0019934]; dopamine metabolic process [GO:0042417]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell growth [GO:0030308]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of cGMP-mediated signaling [GO:0010753]; positive regulation of renal sodium excretion [GO:0035815]; positive regulation of urine volume [GO:0035810]; protein phosphorylation [GO:0006468]; receptor guanylyl cyclase signaling pathway [GO:0007168]; regulation of blood pressure [GO:0008217]; regulation of vascular permeability [GO:0043114]; signal transduction [GO:0007165] GO:0001653; GO:0004383; GO:0004672; GO:0005524; GO:0005525; GO:0005886; GO:0006182; GO:0006468; GO:0007165; GO:0007166; GO:0007168; GO:0007589; GO:0008217; GO:0008528; GO:0010753; GO:0016525; GO:0016941; GO:0017046; GO:0019934; GO:0030308; GO:0035810; GO:0035815; GO:0042417; GO:0042562; GO:0043114; GO:0043235; GO:0048662; GO:0097746; GO:1990620 7438 XM_044317158.1 542 272 169 260 279 Q5XKL5 4.15e-50 BTB/POZ domain-containing protein 8 (AP2-interacting clathrin-endocytosis) (APache) Homo sapiens (Human) NA GO:0005634; GO:0005654; GO:0030136; GO:0030424; GO:0098793 7439 XM_029327416.2 531 1188 949 857 1465 P29702 8.84e-131 Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (EC 2.5.1.58) (EC 2.5.1.59) (CAAX farnesyltransferase subunit alpha) (FTase-alpha) (Ras proteins prenyltransferase subunit alpha) (Type I protein geranyl-geranyltransferase subunit alpha) (GGTase-I-alpha) Bos taurus (Bovine) protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344] GO:0004660; GO:0004661; GO:0004662; GO:0005953; GO:0005965; GO:0018343; GO:0018344 7440 XM_044315357.1 3 10 44 2 6 NA NA NA NA NA NA 7441 XM_044315621.1 8 1 1 0 1 NA NA NA NA NA NA 7442 XM_029331599.2 679 766 383 534 713 Q8CES0 1.23e-76 N-alpha-acetyltransferase 30 (EC 2.3.1.256) (N-acetyltransferase 12) (N-acetyltransferase MAK3 homolog) (NatC catalytic subunit) Mus musculus (Mouse) N-terminal peptidyl-methionine acetylation [GO:0017196] GO:0004596; GO:0005634; GO:0005737; GO:0005829; GO:0005844; GO:0017196; GO:0031417 7443 XR_006393061.1 41 2 25 5 151 NA NA NA NA NA NA 7444 XM_029336987.2 9739 10015 6385 11094 9397 NA NA NA NA NA NA 7445 XM_029330096.2 0 0 0 0 36 NA NA NA NA NA NA 7446 XM_044307437.1 0 5 2 14 0 Q09575 2.49e-52 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 7447 XM_044314957.1 32 19 5 20 46 B8UU78 0 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 7448 XM_044327604.1 4 15 0 4 123 NA NA NA NA NA NA 7449 XM_044312902.1 306 174 181 475 298 Q7Z442 8.78e-70 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Homo sapiens (Human) detection of mechanical stimulus [GO:0050982] GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 7450 XM_044312902.1 306 174 181 475 298 Q7Z442 2.69e-64 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Homo sapiens (Human) detection of mechanical stimulus [GO:0050982] GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 7451 XM_044315441.1 86 137 41 23 16 NA NA NA NA NA NA 7452 XR_006396604.1 31 47 26 6 56 NA NA NA NA NA NA 7453 XM_029333889.2 0 44 55 0 4 P34949 8.58e-137 Mannose-6-phosphate isomerase (EC 5.3.1.8) (Phosphohexomutase) (Phosphomannose isomerase) (PMI) Homo sapiens (Human) GDP-mannose biosynthetic process [GO:0009298]; mannose to fructose-6-phosphate metabolic process [GO:0061611] GO:0004476; GO:0005829; GO:0008270; GO:0009298; GO:0061611; GO:0070062 7454 XM_044324097.1 14 12 10 34 0 Q94K49 2.14e-38 Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1 (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) epigenetic regulation of gene expression [GO:0040029] GO:0003682; GO:0004518; GO:0005634; GO:0035098; GO:0035102; GO:0040029; GO:0046872 7455 XR_003822848.2 0 0 28 0 256 NA NA NA NA NA NA 7456 XR_006393994.1 134 163 77 300 407 NA NA NA NA NA NA 7457 XM_029332028.2 1423 1466 520 909 1424 P16152 5.2e-72 Carbonyl reductase [NADPH] 1 (EC 1.1.1.184) (15-hydroxyprostaglandin dehydrogenase [NADP(+)]) (EC 1.1.1.196, EC 1.1.1.197) (20-beta-hydroxysteroid dehydrogenase) (Alcohol dehydrogenase [NAD(P)+] CBR1) (EC 1.1.1.71) (NADPH-dependent carbonyl reductase 1) (Prostaglandin 9-ketoreductase) (PG-9-KR) (Prostaglandin-E(2) 9-reductase) (EC 1.1.1.189) (Short chain dehydrogenase/reductase family 21C member 1) Homo sapiens (Human) cyclooxygenase pathway [GO:0019371]; epithelial cell differentiation [GO:0030855]; glucocorticoid metabolic process [GO:0008211]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; vitamin K metabolic process [GO:0042373]; xenobiotic metabolic process [GO:0006805] GO:0004090; GO:0005829; GO:0006805; GO:0008106; GO:0008211; GO:0016491; GO:0016616; GO:0016655; GO:0019371; GO:0030855; GO:0042373; GO:0047020; GO:0047021; GO:0050221; GO:0070062; GO:1903561; GO:2000379 7458 XM_029333624.2 32 0 69 17 65 P16066 6.87e-67 Atrial natriuretic peptide receptor 1 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type A) (ANP-A) (ANPR-A) (NPR-A) (Guanylate cyclase A) (GC-A) Homo sapiens (Human) blood vessel diameter maintenance [GO:0097746]; body fluid secretion [GO:0007589]; cell surface receptor signaling pathway [GO:0007166]; cGMP biosynthetic process [GO:0006182]; cGMP-mediated signaling [GO:0019934]; dopamine metabolic process [GO:0042417]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell growth [GO:0030308]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of cGMP-mediated signaling [GO:0010753]; positive regulation of renal sodium excretion [GO:0035815]; positive regulation of urine volume [GO:0035810]; protein phosphorylation [GO:0006468]; receptor guanylyl cyclase signaling pathway [GO:0007168]; regulation of blood pressure [GO:0008217]; regulation of vascular permeability [GO:0043114]; signal transduction [GO:0007165] GO:0001653; GO:0004383; GO:0004672; GO:0005524; GO:0005525; GO:0005886; GO:0006182; GO:0006468; GO:0007165; GO:0007166; GO:0007168; GO:0007589; GO:0008217; GO:0008528; GO:0010753; GO:0016525; GO:0016941; GO:0017046; GO:0019934; GO:0030308; GO:0035810; GO:0035815; GO:0042417; GO:0042562; GO:0043114; GO:0043235; GO:0048662; GO:0097746; GO:1990620 7459 XR_006395701.1 62 57 38 191 79 C3ZQF9 3.78e-23 QRFP-like peptide receptor Branchiostoma floridae (Florida lancelet) (Amphioxus) cellular response to peptide [GO:1901653]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:1901653 7460 XM_044318853.1 2155 1323 3313 4460 5494 NA NA NA NA NA NA 7461 XM_029341048.2 129 60 74 195 154 NA NA NA NA NA NA 7462 XM_044313704.1 9 6 11 7 8 NA NA NA NA NA NA 7463 XM_044308145.1 7 51 35 0 0 P05166 0 Propionyl-CoA carboxylase beta chain, mitochondrial (PCCase subunit beta) (EC 6.4.1.3) (Propanoyl-CoA:carbon dioxide ligase subunit beta) Homo sapiens (Human) branched-chain amino acid metabolic process [GO:0009081]; fatty acid metabolic process [GO:0006631]; short-chain fatty acid catabolic process [GO:0019626] GO:0004658; GO:0005524; GO:0005739; GO:0005759; GO:0005829; GO:0006631; GO:0009081; GO:0019626; GO:1902494 7464 XM_029355450.2 753 371 449 556 655 Q8UVC3 0 Inversin Gallus gallus (Chicken) Wnt signaling pathway [GO:0016055] GO:0005516; GO:0005737; GO:0005856; GO:0016055 7465 XM_044310116.1 132 216 28 207 474 NA NA NA NA NA NA 7466 XM_044319075.1 488 834 505 484 1411 P61222 0 ATP-binding cassette sub-family E member 1 (RNase L inhibitor) (Ribonuclease 4 inhibitor) (RNS4I) Mus musculus (Mouse) negative regulation of endoribonuclease activity [GO:0060702]; nucleobase-containing small molecule metabolic process [GO:0055086]; regulation of translation [GO:0006417]; ribosomal subunit export from nucleus [GO:0000054]; translational initiation [GO:0006413]; translational termination [GO:0006415] GO:0000054; GO:0005506; GO:0005524; GO:0005737; GO:0005739; GO:0005829; GO:0006413; GO:0006415; GO:0006417; GO:0016887; GO:0043024; GO:0051539; GO:0055086; GO:0060698; GO:0060702 7467 XM_029331020.2 41 10 40 7 180 NA NA NA NA NA NA 7468 XM_044318682.1 24 0 0 168 0 Q6B858 7.19e-96 Fibronectin type 3 and ankyrin repeat domains protein 1 (GV14) Bos taurus (Bovine) positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of apoptotic process [GO:0042981] GO:0005634; GO:0005829; GO:0005929; GO:0036064; GO:0042981; GO:0045893; GO:0051091 7469 XM_044314963.1 41 59 33 271 163 Q7RTR2 3.14e-67 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 7470 XM_044314963.1 41 59 33 271 163 Q7RTR2 2.59e-64 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 7471 XM_044314963.1 41 59 33 271 163 Q7RTR2 6.66e-64 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 7472 XM_044314963.1 41 59 33 271 163 Q7RTR2 2.38e-63 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 7473 XM_044314963.1 41 59 33 271 163 Q7RTR2 2.86e-53 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 7474 XM_044314963.1 41 59 33 271 163 Q7RTR2 6.5e-53 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 7475 XM_044314963.1 41 59 33 271 163 Q7RTR2 2.65e-32 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 7476 XM_044313039.1 33 11 14 57 20 NA NA NA NA NA NA 7477 XR_003823453.2 3 192 365 52 272 NA NA NA NA NA NA 7478 XM_029336666.2 29 31 26 31 15 Q6ICH7 3.66e-55 Aspartate beta-hydroxylase domain-containing protein 2 (EC 1.14.11.-) Homo sapiens (Human) peptidyl-amino acid modification [GO:0018193] GO:0016020; GO:0018193; GO:0046872; GO:0051213 7479 XM_029332940.2 795 696 1198 942 893 G3V9H8 4.69e-65 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Rattus norvegicus (Rat) cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0007156; GO:0007158; GO:0007169; GO:0007399; GO:0009410; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030182; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0098797 7480 XM_029348908.2 1495 990 708 1408 1032 Q8NA54 0 IQ and ubiquitin-like domain-containing protein Homo sapiens (Human) cilium assembly [GO:0060271]; smoothened signaling pathway [GO:0007224] GO:0001669; GO:0007224; GO:0031514; GO:0060271 7481 XR_006397627.1 1 12 4 12 6 NA NA NA NA NA NA 7482 XM_029356326.2 93 25 0 48 0 A0A1L8H0H2 4.58e-55 NA NA NA NA 7483 XM_029337080.2 66 37 23 58 62 Q5U419 7.65e-36 Major facilitator superfamily domain-containing protein 3 Mus musculus (Mouse) NA GO:0015295; GO:0016020 7484 XM_029330461.2 0 9 4 12 2 Q96DM1 1.8e-37 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 7485 XM_029327191.2 188 138 87 111 237 NA NA NA NA NA NA 7486 XM_029329455.2 432 301 240 353 139 Q13823 0 Nucleolar GTP-binding protein 2 (Autoantigen NGP-1) Homo sapiens (Human) ribosome biogenesis [GO:0042254] GO:0003723; GO:0003924; GO:0005525; GO:0005634; GO:0005730; GO:0016020; GO:0042254 7487 XM_029356495.2 376 257 234 328 292 NA NA NA NA NA NA 7488 XM_044315501.1 79 48 20 42 35 NA NA NA NA NA NA 7489 XM_029331513.2 184 119 35 227 151 NA NA NA NA NA NA 7490 XM_029324039.2 527 179 219 317 318 Q99807 1.16e-53 5-demethoxyubiquinone hydroxylase, mitochondrial (DMQ hydroxylase) (EC 1.14.99.60) (Timing protein clk-1 homolog) (Ubiquinone biosynthesis monooxygenase COQ7) Homo sapiens (Human) determination of adult lifespan [GO:0008340]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression [GO:0010468]; regulation of reactive oxygen species metabolic process [GO:2000377]; ubiquinone biosynthetic process [GO:0006744] GO:0000122; GO:0003682; GO:0005634; GO:0005694; GO:0005739; GO:0005743; GO:0006744; GO:0008340; GO:0008682; GO:0010468; GO:0016709; GO:0031314; GO:0045944; GO:0046872; GO:0110142; GO:2000377 7491 XM_029345476.2 1068 637 344 134 353 Q5NU32 2.44e-71 Amine oxidase [flavin-containing] A (EC 1.4.3.21) (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A) Equus caballus (Horse) catecholamine metabolic process [GO:0006584]; neurotransmitter catabolic process [GO:0042135] GO:0005739; GO:0005741; GO:0006584; GO:0008131; GO:0042135; GO:0050660; GO:0052595; GO:0052596; GO:0097621 7492 XM_044318679.1 509 647 219 548 728 Q3TIX9 0 U4/U6.U5 tri-snRNP-associated protein 2 (Inactive ubiquitin-specific peptidase 39) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; mRNA splicing, via spliceosome [GO:0000398]; protein deubiquitination [GO:0016579]; spliceosomal complex assembly [GO:0000245] GO:0000245; GO:0000398; GO:0004843; GO:0005634; GO:0005654; GO:0005681; GO:0007049; GO:0008270; GO:0016579; GO:0046540; GO:0051301 7493 XM_044316623.1 55 11 25 21 148 NA NA NA NA NA NA 7494 XR_006396115.1 0 8 16 35 11 P0C0R5 1.68e-31 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) Rattus norvegicus (Rat) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006623; GO:0010506; GO:0015630; GO:0016236; GO:0016241; GO:0030242; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 7495 XR_006396115.1 0 8 16 35 11 P0C0R5 1.68e-31 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) Rattus norvegicus (Rat) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006623; GO:0010506; GO:0015630; GO:0016236; GO:0016241; GO:0030242; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 7496 XR_006396115.1 0 8 16 35 11 P0C0R5 1.68e-31 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) Rattus norvegicus (Rat) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006623; GO:0010506; GO:0015630; GO:0016236; GO:0016241; GO:0030242; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 7497 XM_029345241.2 399 609 214 295 222 Q5BJQ6 1.42e-173 Cleavage stimulation factor subunit 1 (Cleavage stimulation factor 50 kDa subunit) (CSTF 50 kDa subunit) (CstF-50) Rattus norvegicus (Rat) mRNA 3'-end processing [GO:0031124] GO:0005654; GO:0005848; GO:0031124 7498 XR_006396283.1 121 136 93 159 283 NA NA NA NA NA NA 7499 XM_044311342.1 38 0 12 0 28 B0S5N4 6.74e-126 Plexin A3 Danio rerio (Zebrafish) (Brachydanio rerio) axon extension [GO:0048675]; branching morphogenesis of a nerve [GO:0048755]; embryonic skeletal joint morphogenesis [GO:0060272]; motor neuron axon guidance [GO:0008045]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of collateral sprouting in absence of injury [GO:0048696]; regulation of GTPase activity [GO:0043087]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287] GO:0002116; GO:0005886; GO:0007162; GO:0008045; GO:0008360; GO:0016020; GO:0017154; GO:0030334; GO:0042802; GO:0043087; GO:0048675; GO:0048696; GO:0048755; GO:0050772; GO:0060272; GO:1902287 7500 XM_044325959.1 116 72 15 47 23 Q9UKD2 2.48e-86 mRNA turnover protein 4 homolog (Ribosome assembly factor MRTO4) Homo sapiens (Human) nuclear-transcribed mRNA catabolic process [GO:0000956]; ribosomal large subunit assembly [GO:0000027]; ribosomal large subunit biogenesis [GO:0042273]; rRNA processing [GO:0006364] GO:0000027; GO:0000956; GO:0003723; GO:0005730; GO:0005737; GO:0006364; GO:0030687; GO:0042273 7501 XM_044325942.1 8 1 5 1 24 NA NA NA NA NA NA 7502 XM_044323644.1 45 3 21 20 93 NA NA NA NA NA NA 7503 XM_029356916.2 442 390 365 693 736 Q9W2U4 3.94e-34 Serine/threonine-protein phosphatase 4 regulatory subunit 2 (PPP4R2-related protein) Drosophila melanogaster (Fruit fly) mitotic cell cycle [GO:0000278]; negative regulation of peptidoglycan recognition protein signaling pathway [GO:0061060]; negative regulation of smoothened signaling pathway [GO:0045879] GO:0000278; GO:0000775; GO:0005634; GO:0005737; GO:0019888; GO:0030289; GO:0045879; GO:0061060 7504 XM_029332810.1 1298 4194 322 4558 10445 NA NA NA NA NA NA 7505 XM_029342773.2 140 137 61 145 254 NA NA NA NA NA NA 7506 XM_044323209.1 18 37 16 0 9 NA NA NA NA NA NA 7507 XM_044322357.1 9 0 31 0 110 NA NA NA NA NA NA 7508 XM_029350762.2 34 0 115 23 26 P51029 1.11e-71 Protein Wnt-8b Danio rerio (Zebrafish) (Brachydanio rerio) canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; commissural neuron axon guidance [GO:0071679]; embryonic pattern specification [GO:0009880]; eye development [GO:0001654]; eye field cell fate commitment involved in camera-type eye formation [GO:0060898]; forebrain development [GO:0030900]; forebrain neuron differentiation [GO:0021879]; hypothalamus development [GO:0021854]; negative regulation of anterior neural cell fate commitment of the neural plate by Wnt signaling pathway [GO:0022002]; neuron differentiation [GO:0030182]; otic placode formation [GO:0043049]; sensory epithelium regeneration [GO:0070654] GO:0001654; GO:0005109; GO:0005125; GO:0005615; GO:0009880; GO:0021854; GO:0021879; GO:0022002; GO:0030182; GO:0030900; GO:0043049; GO:0045165; GO:0060070; GO:0060898; GO:0070654; GO:0071679 7509 XM_044328667.1 0 0 0 0 13 Q6V0K7 6.19e-50 Oncoprotein-induced transcript 3 protein (Liver-specific zona pellucida domain-containing protein) Rattus norvegicus (Rat) urate homeostasis [GO:1903118] GO:0005201; GO:0005509; GO:0005615; GO:0005635; GO:0009986; GO:1903118 7510 XM_044306763.1 184 0 0 15 56 NA NA NA NA NA NA 7511 XM_029332709.2 582 527 412 1001 784 D6REC4 6.96e-117 Cilia- and flagella-associated protein 99 Homo sapiens (Human) NA GO:0031514 7512 XM_044318230.1 14 33 13 13 6 NA NA NA NA NA NA 7513 XM_044327308.1 26 24 5 15 105 Q80XJ3 3.52e-50 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 7514 XM_044327308.1 26 24 5 15 105 Q80XJ3 1.62e-45 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 7515 XM_044327308.1 26 24 5 15 105 Q80XJ3 6.58e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 7516 XM_044327308.1 26 24 5 15 105 Q80XJ3 7.35e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 7517 XM_044327308.1 26 24 5 15 105 Q80XJ3 3.58e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 7518 XM_044327308.1 26 24 5 15 105 Q80XJ3 1.21e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 7519 XM_044327308.1 26 24 5 15 105 Q80XJ3 7.05e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 7520 XM_044327308.1 26 24 5 15 105 Q80XJ3 1.91e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 7521 XM_029357599.2 531 215 201 94 98 Q8R4S6 1.93e-31 Aryl hydrocarbon receptor (Ah receptor) (AhR) Mus musculus castaneus (Southeastern Asian house mouse) cell cycle [GO:0007049]; cellular response to 3-methylcholanthrene [GO:1904682]; circadian regulation of gene expression [GO:0032922]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of T cell mediated immune response to tumor cell [GO:0002841]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of adaptive immune response [GO:0002819]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; response to xenobiotic stimulus [GO:0009410]; transcription by RNA polymerase II [GO:0006366] GO:0000976; GO:0002819; GO:0002841; GO:0004879; GO:0005634; GO:0005737; GO:0006355; GO:0006357; GO:0006366; GO:0007049; GO:0009410; GO:0032922; GO:0034751; GO:0034753; GO:0042803; GO:0045892; GO:0045944; GO:0046982; GO:0070888; GO:1904682; GO:1990837 7522 XR_003827529.2 169 184 80 559 1 NA NA NA NA NA NA 7523 XM_029350919.2 16 115 9 137 27 Q9SY14 7.15e-69 CSC1-like protein At4g02900 Arabidopsis thaliana (Mouse-ear cress) NA GO:0005227; GO:0005886 7524 XM_029341976.2 68 0 0 0 407 Q9CYL5 5.73e-33 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Mus musculus (Mouse) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070374 7525 XM_029341976.2 68 0 0 0 407 Q9CYL5 1.71e-23 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Mus musculus (Mouse) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070374 7526 XM_044317450.1 110 20 27 124 113 Q15034 1.39e-24 Probable E3 ubiquitin-protein ligase HERC3 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 3) (HECT-type E3 ubiquitin transferase HERC3) Homo sapiens (Human) protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0005737; GO:0005829; GO:0006511; GO:0016567; GO:0031410; GO:0061630 7527 XR_006397272.1 0 0 0 16 8 NA NA NA NA NA NA 7528 XM_044309532.1 9 0 12 0 53 NA NA NA NA NA NA 7529 XR_003827737.2 0 6 10 0 2 NA NA NA NA NA NA 7530 XM_044310651.1 0 0 0 9 4 P0CT43 9.8e-84 Transposon Tf2-8 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 7531 XM_029328013.2 47 109 136 432 0 Q803V5 5.54e-171 Target of rapamycin complex subunit lst8 (TORC subunit lst8) (G protein beta subunit-like) (Gable) (Protein GbetaL) (MTOR associated protein, LST8 homolog) Danio rerio (Zebrafish) (Brachydanio rerio) regulation of actin cytoskeleton organization [GO:0032956]; TOR signaling [GO:0031929] GO:0005737; GO:0031929; GO:0031931; GO:0031932; GO:0032956 7532 XM_044326604.1 410 705 440 843 508 NA NA NA NA NA NA 7533 XM_044311033.1 7 23 17 13 9 NA NA NA NA NA NA 7534 XM_044317782.1 80 20 54 0 68 Q6ZNB5 4.65e-28 Protein XNDC1N (XRCC1 N-terminal domain-containing 1 N-terminal like) Homo sapiens (Human) single strand break repair [GO:0000012] GO:0000012; GO:0003684; GO:0005694; GO:0005730 7535 XM_044324672.1 137 214 36 239 35 NA NA NA NA NA NA 7536 XM_044312831.1 14 4 8 12 36 NA NA NA NA NA NA 7537 XR_006398039.1 29 11 24 22 73 NA NA NA NA NA NA 7538 XM_044327440.1 189 154 124 156 127 F1NY98 2.67e-24 Cell adhesion molecule DSCAM (Down syndrome cell adhesion molecule homolog) Gallus gallus (Chicken) axon guidance [GO:0007411]; camera-type eye photoreceptor cell differentiation [GO:0060219]; dendrite morphogenesis [GO:0048813]; dendrite self-avoidance [GO:0070593]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; locomotory behavior [GO:0007626]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of phosphorylation [GO:0042327]; post-embryonic retina morphogenesis in camera-type eye [GO:0060060]; retina layer formation [GO:0010842]; synapse assembly [GO:0007416] GO:0005886; GO:0007156; GO:0007162; GO:0007411; GO:0007416; GO:0007626; GO:0010842; GO:0030425; GO:0030426; GO:0042327; GO:0043025; GO:0045202; GO:0048813; GO:0048842; GO:0060060; GO:0060219; GO:0070593; GO:1990782; GO:1990890 7539 XM_029339136.2 103 106 89 109 94 P23610 3.83e-52 40-kDa huntingtin-associated protein (HAP40) (CpG island protein) (Factor VIII intron 22 protein) Homo sapiens (Human) negative regulation of proteasomal protein catabolic process [GO:1901799]; vesicle cytoskeletal trafficking [GO:0099518] GO:0005634; GO:0005769; GO:0016604; GO:0099518; GO:1901799 7540 XM_044307386.1 1914 1346 1525 2269 2200 Q70CQ2 0 Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.4.19.12) (Deubiquitinating enzyme 34) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) Homo sapiens (Human) positive regulation of canonical Wnt signaling pathway [GO:0090263]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt signaling pathway [GO:0016055] GO:0004197; GO:0004843; GO:0005634; GO:0005829; GO:0006511; GO:0016055; GO:0016579; GO:0071108; GO:0090263 7541 XM_044307386.1 1914 1346 1525 2269 2200 Q70CQ2 1.13e-98 Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.4.19.12) (Deubiquitinating enzyme 34) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) Homo sapiens (Human) positive regulation of canonical Wnt signaling pathway [GO:0090263]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt signaling pathway [GO:0016055] GO:0004197; GO:0004843; GO:0005634; GO:0005829; GO:0006511; GO:0016055; GO:0016579; GO:0071108; GO:0090263 7542 XR_006395936.1 83 20 27 82 68 NA NA NA NA NA NA 7543 XR_006395431.1 0 0 1 6 0 NA NA NA NA NA NA 7544 XM_044312116.1 4 8 13 10 7 NA NA NA NA NA NA 7545 XM_044328745.1 15 100 5 30 24 P49005 4.75e-161 DNA polymerase delta subunit 2 (DNA polymerase delta subunit p50) Homo sapiens (Human) DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; DNA strand elongation involved in DNA replication [GO:0006271]; DNA-templated DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276] GO:0003677; GO:0005634; GO:0005654; GO:0006260; GO:0006261; GO:0006271; GO:0016035; GO:0042276; GO:0042575; GO:0043625; GO:0071897 7546 XM_029342333.2 36 3 0 14 0 P50904 0 Ras GTPase-activating protein 1 (GAP) (GTPase-activating protein) (RasGAP) (Ras p21 protein activator) (p120GAP) Rattus norvegicus (Rat) actin cytoskeleton organization [GO:0030036]; activation of GTPase activity [GO:0090630]; blood vessel morphogenesis [GO:0048514]; cell adhesion [GO:0007155]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; male genitalia development [GO:0030539]; mitotic cytokinesis [GO:0000281]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of glucose import [GO:0046326]; positive regulation of GTPase activity [GO:0043547]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; regulation of actin filament polymerization [GO:0030833]; response to insulin [GO:0032868]; response to xenobiotic stimulus [GO:0009410]; signal transduction [GO:0007165]; vasculogenesis [GO:0001570] GO:0000281; GO:0001570; GO:0001726; GO:0001784; GO:0001934; GO:0001953; GO:0005096; GO:0005102; GO:0005161; GO:0005829; GO:0005886; GO:0007155; GO:0007162; GO:0007165; GO:0009410; GO:0016020; GO:0030036; GO:0030539; GO:0030833; GO:0030971; GO:0031965; GO:0032868; GO:0036120; GO:0043066; GO:0043422; GO:0043524; GO:0043547; GO:0044325; GO:0044344; GO:0044877; GO:0046326; GO:0048146; GO:0048514; GO:0050731; GO:0051020; GO:0071364; GO:0090630; GO:1990782 7547 XM_044322838.1 26 13 10 18 51 NA NA NA NA NA NA 7548 XM_029328649.2 131 162 13 100 79 Q5R6J1 1.69e-87 Sodium-dependent neutral amino acid transporter B(0)AT1 (Solute carrier family 6 member 19) (System B(0) neutral amino acid transporter AT1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0015175; GO:0015293; GO:0016324 7549 XM_029341389.2 566 567 647 626 611 NA NA NA NA NA NA 7550 XM_044325817.1 10 25 0 31 9 Q96AY4 6.32e-114 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7551 XM_044325817.1 10 25 0 31 9 Q96AY4 6.94e-109 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7552 XM_044325817.1 10 25 0 31 9 Q96AY4 2.44e-108 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7553 XM_044325817.1 10 25 0 31 9 Q96AY4 1.05e-104 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7554 XM_044325817.1 10 25 0 31 9 Q96AY4 1.32e-96 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7555 XM_044325817.1 10 25 0 31 9 Q96AY4 4.42e-63 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7556 XM_044325817.1 10 25 0 31 9 Q96AY4 3.15e-52 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7557 XM_029332392.2 15 37 35 34 44 Q8BG58 4.21e-67 Transmembrane prolyl 4-hydroxylase (P4H-TM) (EC 1.14.11.29) (Hypoxia-inducible factor prolyl hydroxylase 4) (HIF-PH4) (HIF-prolyl hydroxylase 4) (HPH-4) Mus musculus (Mouse) peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; regulation of erythrocyte differentiation [GO:0045646] GO:0004656; GO:0005506; GO:0005509; GO:0005783; GO:0005789; GO:0016706; GO:0018401; GO:0031418; GO:0045646 7558 XM_029332392.2 15 37 35 34 44 Q8BG58 1.35e-59 Transmembrane prolyl 4-hydroxylase (P4H-TM) (EC 1.14.11.29) (Hypoxia-inducible factor prolyl hydroxylase 4) (HIF-PH4) (HIF-prolyl hydroxylase 4) (HPH-4) Mus musculus (Mouse) peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; regulation of erythrocyte differentiation [GO:0045646] GO:0004656; GO:0005506; GO:0005509; GO:0005783; GO:0005789; GO:0016706; GO:0018401; GO:0031418; GO:0045646 7559 XM_044315450.1 529 316 398 277 329 NA NA NA NA NA NA 7560 XM_044307087.1 3 1 1 22 93 NA NA NA NA NA NA 7561 XM_029355905.2 26 20 0 17 37 NA NA NA NA NA NA 7562 XM_029329031.2 136 64 49 126 158 Q80Z37 2.36e-28 E3 ubiquitin-protein ligase Topors (EC 2.3.2.27) (RING-type E3 ubiquitin transferase Topors) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3) Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; maintenance of protein location in nucleus [GO:0051457]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K48-linked ubiquitination [GO:0070936]; protein localization to nucleus [GO:0034504]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein sumoylation [GO:0016925]; regulation of cell population proliferation [GO:0042127]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000151; GO:0000209; GO:0000922; GO:0000930; GO:0003677; GO:0003823; GO:0004842; GO:0005634; GO:0005654; GO:0005814; GO:0006511; GO:0006513; GO:0006974; GO:0008630; GO:0016605; GO:0016607; GO:0016925; GO:0019789; GO:0032391; GO:0034504; GO:0036064; GO:0042127; GO:0042771; GO:0043161; GO:0044547; GO:0045893; GO:0046872; GO:0051443; GO:0051457; GO:0061630; GO:0070936 7563 XM_029357807.2 14 0 1 4 14 NA NA NA NA NA NA 7564 XM_044318294.1 1519 545 76 722 2742 NA NA NA NA NA NA 7565 XM_029341402.2 26 25 10 9 0 NA NA NA NA NA NA 7566 XM_044318928.1 177 263 96 197 207 O54857 7.97e-108 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (EC 3.1.3.16) (EC 3.1.3.48) (EC 3.1.3.67) (Phosphatase and tensin homolog) Rattus norvegicus (Rat) adult behavior [GO:0030534]; aging [GO:0007568]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; B cell proliferation [GO:0042100]; brain morphogenesis [GO:0048854]; canonical Wnt signaling pathway [GO:0060070]; cardiac muscle tissue development [GO:0048738]; cell migration [GO:0016477]; cell motility [GO:0048870]; cell population proliferation [GO:0008283]; cellular response to decreased oxygen levels [GO:0036294]; cellular response to electrical stimulus [GO:0071257]; cellular response to ethanol [GO:0071361]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to leptin stimulus [GO:0044320]; cellular response to nerve growth factor stimulus [GO:1990090]; central nervous system development [GO:0007417]; central nervous system myelin maintenance [GO:0032286]; central nervous system neuron axonogenesis [GO:0021955]; dendritic spine morphogenesis [GO:0060997]; dentate gyrus development [GO:0021542]; dephosphorylation [GO:0016311]; endothelial cell migration [GO:0043542]; forebrain morphogenesis [GO:0048853]; heart development [GO:0007507]; inositol phosphate dephosphorylation [GO:0046855]; learning or memory [GO:0007611]; locomotor rhythm [GO:0045475]; locomotory behavior [GO:0007626]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; male mating behavior [GO:0060179]; maternal behavior [GO:0042711]; memory [GO:0007613]; multicellular organismal response to stress [GO:0033555]; myelination [GO:0042552]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axon regeneration [GO:0048681]; negative regulation of axonogenesis [GO:0050771]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell cycle G1/S phase transition [GO:1902807]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of cellular senescence [GO:2000773]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of defense response to bacterium [GO:1900425]; negative regulation of dendrite extension [GO:1903860]; negative regulation of dendritic spine morphogenesis [GO:0061002]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of keratinocyte migration [GO:0051548]; negative regulation of myelination [GO:0031642]; negative regulation of neuron projection development [GO:0010977]; negative regulation of organ growth [GO:0046621]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of phagocytosis [GO:0050765]; negative regulation of phagocytosis, engulfment [GO:0060101]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of ribosome biogenesis [GO:0090071]; negative regulation of signaling receptor activity [GO:2000272]; negative regulation of synaptic vesicle clustering [GO:2000808]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of vascular associated smooth muscle cell proliferation [GO:1904706]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; neuron projection development [GO:0031175]; neuron-neuron synaptic transmission [GO:0007270]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol dephosphorylation [GO:0046856]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of TRAIL-activated apoptotic signaling pathway [GO:1903984]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; postsynaptic density assembly [GO:0097107]; prepulse inhibition [GO:0060134]; presynaptic membrane assembly [GO:0097105]; prostate gland growth [GO:0060736]; protein dephosphorylation [GO:0006470]; protein kinase B signaling [GO:0043491]; protein stabilization [GO:0050821]; regulation of axon regeneration [GO:0048679]; regulation of B cell apoptotic process [GO:0002902]; regulation of cell cycle [GO:0051726]; regulation of cellular component size [GO:0032535]; regulation of cellular localization [GO:0060341]; regulation of macrophage apoptotic process [GO:2000109]; regulation of myeloid cell apoptotic process [GO:0033032]; regulation of neuron projection development [GO:0010975]; regulation of protein kinase B signaling [GO:0051896]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to activity [GO:0014823]; response to arsenic-containing substance [GO:0046685]; response to ATP [GO:0033198]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to glucose [GO:0009749]; response to inorganic substance [GO:0010035]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to xenobiotic stimulus [GO:0009410]; response to zinc ion [GO:0010043]; rhythmic synaptic transmission [GO:0060024]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; synapse maturation [GO:0060074]; T cell proliferation [GO:0042098] GO:0001525; GO:0001933; GO:0002902; GO:0004438; GO:0004721; GO:0004722; GO:0004725; GO:0005161; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0005886; GO:0006470; GO:0006915; GO:0007270; GO:0007416; GO:0007417; GO:0007507; GO:0007568; GO:0007584; GO:0007611; GO:0007613; GO:0007626; GO:0008138; GO:0008283; GO:0008284; GO:0008285; GO:0009410; GO:0009749; GO:0009898; GO:0010033; GO:0010035; GO:0010043; GO:0010628; GO:0010666; GO:0010719; GO:0010975; GO:0010977; GO:0010997; GO:0014065; GO:0014069; GO:0014070; GO:0014823; GO:0016311; GO:0016314; GO:0016324; GO:0016477; GO:0016605; GO:0016791; GO:0017018; GO:0019899; GO:0019901; GO:0021542; GO:0021955; GO:0030165; GO:0030336; GO:0030534; GO:0030889; GO:0031175; GO:0031642; GO:0031647; GO:0032228; GO:0032286; GO:0032355; GO:0032535; GO:0032869; GO:0033032; GO:0033137; GO:0033198; GO:0033555; GO:0035176; GO:0035255; GO:0035749; GO:0036294; GO:0042098; GO:0042100; GO:0042130; GO:0042552; GO:0042711; GO:0042802; GO:0042995; GO:0043005; GO:0043065; GO:0043066; GO:0043197; GO:0043220; GO:0043491; GO:0043542; GO:0044320; GO:0045211; GO:0045471; GO:0045475; GO:0045666; GO:0045736; GO:0045786; GO:0045792; GO:0046621; GO:0046685; GO:0046855; GO:0046856; GO:0048008; GO:0048679; GO:0048681; GO:0048738; GO:0048853; GO:0048854; GO:0048870; GO:0050680; GO:0050765; GO:0050771; GO:0050821; GO:0051091; GO:0051548; GO:0051717; GO:0051726; GO:0051800; GO:0051895; GO:0051896; GO:0051898; GO:0060024; GO:0060044; GO:0060070; GO:0060074; GO:0060101; GO:0060134; GO:0060179; GO:0060291; GO:0060292; GO:0060341; GO:0060736; GO:0060997; GO:0061002; GO:0070373; GO:0070374; GO:0071257; GO:0071361; GO:0071456; GO:0090071; GO:0090394; GO:0097105; GO:0097107; GO:0099524; GO:1900425; GO:1901017; GO:1902807; GO:1903690; GO:1903860; GO:1903984; GO:1904668; GO:1904706; GO:1990090; GO:1990314; GO:1990381; GO:1990782; GO:2000060; GO:2000109; GO:2000134; GO:2000272; GO:2000463; GO:2000773; GO:2000808; GO:2001235 7567 XM_044313110.1 71 135 35 25 111 NA NA NA NA NA NA 7568 XR_003827019.2 149 161 125 218 154 NA NA NA NA NA NA 7569 XM_044321115.1 60 38 180 152 158 Q9H1A4 0 Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Mitotic checkpoint regulator) (Testis-specific gene 24 protein) Homo sapiens (Human) anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; metaphase/anaphase transition of mitotic cell cycle [GO:0007091]; protein K11-linked ubiquitination [GO:0070979]; regulation of meiotic cell cycle [GO:0051445]; regulation of mitotic cell cycle [GO:0007346] GO:0005654; GO:0005680; GO:0005829; GO:0007091; GO:0007346; GO:0031145; GO:0051301; GO:0051445; GO:0060090; GO:0070979 7570 XM_044317603.1 4 8 10 7 48 NA NA NA NA NA NA 7571 XM_029327010.2 20 0 2 0 0 Q5BKQ4 1.48e-60 Inactive pancreatic lipase-related protein 1 (PL-RP1) Mus musculus (Mouse) lipid metabolic process [GO:0006629] GO:0004806; GO:0005509; GO:0005615; GO:0006629; GO:0016298 7572 XM_044313245.1 618 557 184 0 439 NA NA NA NA NA NA 7573 XM_029327922.2 1 0 0 2 11 NA NA NA NA NA NA 7574 XM_044329147.1 12 0 9 1 0 NA NA NA NA NA NA 7575 XM_029343977.2 0 0 147 75 0 B9EJ86 0 Oxysterol-binding protein-related protein 8 (ORP-8) (OSBP-related protein 8) Mus musculus (Mouse) activation of protein kinase B activity [GO:0032148]; fat cell differentiation [GO:0045444]; negative regulation of cell migration [GO:0030336]; negative regulation of sequestering of triglyceride [GO:0010891]; phospholipid transport [GO:0015914]; positive regulation of glucose import [GO:0046326]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of protein kinase B signaling [GO:0051897]; protein localization to nuclear pore [GO:0090204] GO:0001786; GO:0005783; GO:0005789; GO:0005829; GO:0010891; GO:0015248; GO:0015485; GO:0015914; GO:0016020; GO:0030336; GO:0031965; GO:0032148; GO:0032541; GO:0032934; GO:0043231; GO:0045444; GO:0046326; GO:0046628; GO:0051897; GO:0070273; GO:0090204; GO:0140343 7576 XM_029337425.2 0 0 0 0 16 NA NA NA NA NA NA 7577 XR_006397652.1 0 9 13 8 0 NA NA NA NA NA NA 7578 XM_029355853.2 75 63 63 81 130 NA NA NA NA NA NA 7579 XM_029341177.2 714 503 685 902 599 A4IHD2 4.33e-165 Helicase ARIP4 (EC 3.6.4.12) (Androgen receptor-interacting protein 4) (RAD54-like protein 2) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0003677; GO:0004386; GO:0005524; GO:0005634; GO:0016887; GO:0140658 7580 XM_029341177.2 714 503 685 902 599 A4IHD2 1.59e-86 Helicase ARIP4 (EC 3.6.4.12) (Androgen receptor-interacting protein 4) (RAD54-like protein 2) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0003677; GO:0004386; GO:0005524; GO:0005634; GO:0016887; GO:0140658 7581 XR_006397014.1 66 66 18 37 52 NA NA NA NA NA NA 7582 XM_029337757.2 25 13 14 4 34 NA NA NA NA NA NA 7583 XM_029323797.2 323 344 126 243 85 Q5M823 1.55e-64 NudC domain-containing protein 2 Rattus norvegicus (Rat) protein folding [GO:0006457] GO:0000776; GO:0000922; GO:0005737; GO:0005815; GO:0005829; GO:0006457; GO:0045171; GO:0051082; GO:0072686 7584 XM_044316994.1 54 43 14 14 42 Q5XGG3 4.44e-47 PIH1 domain-containing protein 2 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA NA 7585 XR_006395112.1 83 32 42 45 46 NA NA NA NA NA NA 7586 XR_006394520.1 30 13 85 256 59 NA NA NA NA NA NA 7587 XR_006397388.1 257 147 40 52 9 NA NA NA NA NA NA 7588 XR_003825610.2 524 283 287 438 565 NA NA NA NA NA NA 7589 XM_029346327.2 9 0 0 18 29 NA NA NA NA NA NA 7590 XM_029335181.2 1002 198 336 546 378 Q5PR73 2.75e-31 GTP-binding protein Di-Ras2 (Distinct subgroup of the Ras family member 2) Mus musculus (Mouse) signal transduction [GO:0007165] GO:0003924; GO:0005525; GO:0005886; GO:0007165; GO:0019003 7591 XM_044327529.1 0 24 0 15 0 Q08BV2 2.44e-133 tRNA wybutosine-synthesizing protein 5 (EC 1.14.11.42) (tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-C(2))-hydroxylase) Danio rerio (Zebrafish) (Brachydanio rerio) wybutosine biosynthetic process [GO:0031591] GO:0000049; GO:0005506; GO:0016706; GO:0031591; GO:0042803; GO:0102524 7592 XM_029326351.2 105 8 57 8 188 P0CT39 5.85e-87 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 7593 XM_029352299.2 8 0 0 0 0 Q9SF91 2.32e-36 Ras-related protein RABE1e (AtRABE1e) (Ras-related protein Rab8E) (AtRab8E) Arabidopsis thaliana (Mouse-ear cress) protein secretion [GO:0009306]; regulation of exocytosis [GO:0017157]; vesicle docking involved in exocytosis [GO:0006904] GO:0000139; GO:0003924; GO:0005525; GO:0005829; GO:0005886; GO:0006904; GO:0009306; GO:0017157; GO:0043231 7594 XM_029342663.2 373 21 19 685 695 NA NA NA NA NA NA 7595 XM_044310440.1 713 1318 542 1522 1102 O46385 1.01e-179 Supervillin (Archvillin) (p205/p250) Bos taurus (Bovine) actin filament severing [GO:0051014]; actin polymerization or depolymerization [GO:0008154]; barbed-end actin filament capping [GO:0051016]; positive regulation of cytokinesis [GO:0032467] GO:0002102; GO:0005546; GO:0005737; GO:0008154; GO:0015629; GO:0030496; GO:0032154; GO:0032467; GO:0036449; GO:0042995; GO:0051014; GO:0051015; GO:0051016; GO:0060090; GO:0070161 7596 XM_044309913.1 0 12 9 45 7 NA NA NA NA NA NA 7597 XM_044328443.1 5 195 55 211 117 NA NA NA NA NA NA 7598 XM_029353578.2 302 113 482 653 231 P22083 1.24e-42 Alpha-(1,3)-fucosyltransferase 4 (4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase) (EC 2.4.1.152) (ELAM-1 ligand fucosyltransferase) (Fucosyltransferase 4) (Fucosyltransferase IV) (Fuc-TIV) (FucT-IV) (Galactoside 3-L-fucosyltransferase) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; fucosylation [GO:0036065]; glycosphingolipid biosynthetic process [GO:0006688]; inflammatory response [GO:0006954]; L-fucose catabolic process [GO:0042355]; lymphocyte migration into lymph node [GO:0097022]; oligosaccharide biosynthetic process [GO:0009312]; oligosaccharide metabolic process [GO:0009311]; positive regulation of leukocyte tethering or rolling [GO:1903238]; positive regulation of neutrophil migration [GO:1902624]; protein glycosylation [GO:0006486]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493]; regulation of leukocyte cell-cell adhesion [GO:1903037] GO:0000139; GO:0005794; GO:0005802; GO:0005975; GO:0006486; GO:0006487; GO:0006493; GO:0006688; GO:0006954; GO:0008417; GO:0009311; GO:0009312; GO:0009986; GO:0016020; GO:0017083; GO:0032580; GO:0036065; GO:0042355; GO:0046920; GO:0071944; GO:0097022; GO:1902624; GO:1903037; GO:1903238 7599 XM_044316500.1 6 12 0 16 7 NA NA NA NA NA NA 7600 XM_044319183.1 309 323 282 425 78 NA NA NA NA NA NA 7601 XM_029355270.2 193 823 0 2 1706 NA NA NA NA NA NA 7602 XR_006395220.1 186 123 235 178 639 NA NA NA NA NA NA 7603 XR_006397096.1 224 41 22 26 114 Q60997 6.86e-54 Deleted in malignant brain tumors 1 protein (Apactin) (CRP-ductin) (Glycoprotein 300) (gp300) (Hensin) (Mucin-like glycoprotein) (Muclin) (Vomeroglandin) (p80) Mus musculus (Mouse) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blastocyst development [GO:0001824]; columnar/cuboidal epithelial cell differentiation [GO:0002065]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterial lipoprotein [GO:0042494]; induction of bacterial agglutination [GO:0043152]; inner cell mass cell proliferation [GO:0001833]; positive regulation of epithelial cell differentiation [GO:0030858]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617] GO:0001530; GO:0001824; GO:0001833; GO:0002065; GO:0003677; GO:0005044; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0009617; GO:0015031; GO:0019898; GO:0030658; GO:0030670; GO:0030858; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0050829; GO:0050830; GO:0050840; GO:0061844; GO:0062023; GO:0070891; GO:1904399 7604 XR_006397096.1 224 41 22 26 114 Q60997 2.89e-52 Deleted in malignant brain tumors 1 protein (Apactin) (CRP-ductin) (Glycoprotein 300) (gp300) (Hensin) (Mucin-like glycoprotein) (Muclin) (Vomeroglandin) (p80) Mus musculus (Mouse) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blastocyst development [GO:0001824]; columnar/cuboidal epithelial cell differentiation [GO:0002065]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterial lipoprotein [GO:0042494]; induction of bacterial agglutination [GO:0043152]; inner cell mass cell proliferation [GO:0001833]; positive regulation of epithelial cell differentiation [GO:0030858]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617] GO:0001530; GO:0001824; GO:0001833; GO:0002065; GO:0003677; GO:0005044; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0009617; GO:0015031; GO:0019898; GO:0030658; GO:0030670; GO:0030858; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0050829; GO:0050830; GO:0050840; GO:0061844; GO:0062023; GO:0070891; GO:1904399 7605 XR_006397096.1 224 41 22 26 114 Q60997 9.45e-52 Deleted in malignant brain tumors 1 protein (Apactin) (CRP-ductin) (Glycoprotein 300) (gp300) (Hensin) (Mucin-like glycoprotein) (Muclin) (Vomeroglandin) (p80) Mus musculus (Mouse) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blastocyst development [GO:0001824]; columnar/cuboidal epithelial cell differentiation [GO:0002065]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterial lipoprotein [GO:0042494]; induction of bacterial agglutination [GO:0043152]; inner cell mass cell proliferation [GO:0001833]; positive regulation of epithelial cell differentiation [GO:0030858]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617] GO:0001530; GO:0001824; GO:0001833; GO:0002065; GO:0003677; GO:0005044; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0009617; GO:0015031; GO:0019898; GO:0030658; GO:0030670; GO:0030858; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0050829; GO:0050830; GO:0050840; GO:0061844; GO:0062023; GO:0070891; GO:1904399 7606 XR_006397096.1 224 41 22 26 114 Q60997 4.13e-51 Deleted in malignant brain tumors 1 protein (Apactin) (CRP-ductin) (Glycoprotein 300) (gp300) (Hensin) (Mucin-like glycoprotein) (Muclin) (Vomeroglandin) (p80) Mus musculus (Mouse) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blastocyst development [GO:0001824]; columnar/cuboidal epithelial cell differentiation [GO:0002065]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterial lipoprotein [GO:0042494]; induction of bacterial agglutination [GO:0043152]; inner cell mass cell proliferation [GO:0001833]; positive regulation of epithelial cell differentiation [GO:0030858]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617] GO:0001530; GO:0001824; GO:0001833; GO:0002065; GO:0003677; GO:0005044; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0009617; GO:0015031; GO:0019898; GO:0030658; GO:0030670; GO:0030858; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0050829; GO:0050830; GO:0050840; GO:0061844; GO:0062023; GO:0070891; GO:1904399 7607 XR_006397096.1 224 41 22 26 114 Q60997 2.11e-50 Deleted in malignant brain tumors 1 protein (Apactin) (CRP-ductin) (Glycoprotein 300) (gp300) (Hensin) (Mucin-like glycoprotein) (Muclin) (Vomeroglandin) (p80) Mus musculus (Mouse) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blastocyst development [GO:0001824]; columnar/cuboidal epithelial cell differentiation [GO:0002065]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterial lipoprotein [GO:0042494]; induction of bacterial agglutination [GO:0043152]; inner cell mass cell proliferation [GO:0001833]; positive regulation of epithelial cell differentiation [GO:0030858]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617] GO:0001530; GO:0001824; GO:0001833; GO:0002065; GO:0003677; GO:0005044; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0009617; GO:0015031; GO:0019898; GO:0030658; GO:0030670; GO:0030858; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0050829; GO:0050830; GO:0050840; GO:0061844; GO:0062023; GO:0070891; GO:1904399 7608 XR_006397096.1 224 41 22 26 114 Q60997 5.46e-24 Deleted in malignant brain tumors 1 protein (Apactin) (CRP-ductin) (Glycoprotein 300) (gp300) (Hensin) (Mucin-like glycoprotein) (Muclin) (Vomeroglandin) (p80) Mus musculus (Mouse) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blastocyst development [GO:0001824]; columnar/cuboidal epithelial cell differentiation [GO:0002065]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterial lipoprotein [GO:0042494]; induction of bacterial agglutination [GO:0043152]; inner cell mass cell proliferation [GO:0001833]; positive regulation of epithelial cell differentiation [GO:0030858]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617] GO:0001530; GO:0001824; GO:0001833; GO:0002065; GO:0003677; GO:0005044; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0009617; GO:0015031; GO:0019898; GO:0030658; GO:0030670; GO:0030858; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0050829; GO:0050830; GO:0050840; GO:0061844; GO:0062023; GO:0070891; GO:1904399 7609 XR_006397096.1 224 41 22 26 114 Q60997 1.18e-21 Deleted in malignant brain tumors 1 protein (Apactin) (CRP-ductin) (Glycoprotein 300) (gp300) (Hensin) (Mucin-like glycoprotein) (Muclin) (Vomeroglandin) (p80) Mus musculus (Mouse) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blastocyst development [GO:0001824]; columnar/cuboidal epithelial cell differentiation [GO:0002065]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterial lipoprotein [GO:0042494]; induction of bacterial agglutination [GO:0043152]; inner cell mass cell proliferation [GO:0001833]; positive regulation of epithelial cell differentiation [GO:0030858]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617] GO:0001530; GO:0001824; GO:0001833; GO:0002065; GO:0003677; GO:0005044; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0009617; GO:0015031; GO:0019898; GO:0030658; GO:0030670; GO:0030858; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0050829; GO:0050830; GO:0050840; GO:0061844; GO:0062023; GO:0070891; GO:1904399 7610 XM_044310538.1 0 4 5 1 39 NA NA NA NA NA NA 7611 XM_029355662.2 31 9 0 30 0 NA NA NA NA NA NA 7612 XR_006392535.1 118 25 70 95 111 NA NA NA NA NA NA 7613 XM_044323025.1 380 955 187 1376 634 P02466 4.01e-46 Collagen alpha-2(I) chain (Alpha-2 type I collagen) Rattus norvegicus (Rat) blood vessel development [GO:0001568]; bone mineralization [GO:0030282]; cellular response to amino acid stimulus [GO:0071230]; cellular response to organic substance [GO:0071310]; cellular response to retinoic acid [GO:0071300]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; extracellular matrix assembly [GO:0085029]; extracellular matrix organization [GO:0030198]; protein heterotrimerization [GO:0070208]; regulation of blood pressure [GO:0008217]; response to norepinephrine [GO:0071873]; Rho protein signal transduction [GO:0007266]; skeletal system development [GO:0001501]; skin morphogenesis [GO:0043589]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001501; GO:0001568; GO:0002020; GO:0005201; GO:0005576; GO:0005581; GO:0005584; GO:0005615; GO:0007179; GO:0007266; GO:0008217; GO:0030198; GO:0030199; GO:0030282; GO:0030674; GO:0031012; GO:0032963; GO:0042802; GO:0043589; GO:0046332; GO:0046872; GO:0048407; GO:0062023; GO:0070208; GO:0071230; GO:0071300; GO:0071310; GO:0071873; GO:0085029; GO:0097067 7614 XM_029338604.2 0 0 12 7 1 NA NA NA NA NA NA 7615 XM_044317093.1 11 253 0 145 551 P11530 0 Dystrophin Rattus norvegicus (Rat) actin cytoskeleton organization [GO:0030036]; aging [GO:0007568]; cardiac muscle cell action potential [GO:0086001]; cardiac muscle contraction [GO:0060048]; cell differentiation [GO:0030154]; cerebral cortex development [GO:0021987]; establishment of blood-nerve barrier [GO:0008065]; establishment of glial blood-brain barrier [GO:0060857]; muscle cell cellular homeostasis [GO:0046716]; muscle cell development [GO:0055001]; muscle cell differentiation [GO:0042692]; muscle organ development [GO:0007517]; myotube cell development [GO:0014904]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of peptidyl-cysteine S-nitrosylation [GO:1902083]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; neuron development [GO:0048666]; neuron differentiation [GO:0030182]; neuron projection morphogenesis [GO:0048812]; neurotransmitter receptor metabolic process [GO:0045213]; nucleus localization [GO:0051647]; olfactory nerve structural organization [GO:0021629]; peptide biosynthetic process [GO:0043043]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neuron projection development [GO:0010976]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; protein localization [GO:0008104]; protein-containing complex assembly [GO:0065003]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell cycle [GO:0051726]; regulation of cellular response to growth factor stimulus [GO:0090287]; regulation of DNA-templated transcription [GO:0006355]; regulation of gene expression [GO:0010468]; regulation of heart rate [GO:0002027]; regulation of membrane potential [GO:0042391]; regulation of muscle system process [GO:0090257]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of skeletal muscle contraction [GO:0014819]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; regulation of voltage-gated calcium channel activity [GO:1901385]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; response to muscle stretch [GO:0035994]; response to water deprivation [GO:0009414]; skeletal muscle tissue development [GO:0007519]; skeletal muscle tissue regeneration [GO:0043403] GO:0001954; GO:0002027; GO:0002162; GO:0003779; GO:0005178; GO:0005521; GO:0005634; GO:0005741; GO:0005794; GO:0005840; GO:0005883; GO:0005886; GO:0006355; GO:0007517; GO:0007519; GO:0007568; GO:0008065; GO:0008104; GO:0008270; GO:0008284; GO:0008307; GO:0009414; GO:0009986; GO:0010468; GO:0010880; GO:0010881; GO:0010976; GO:0014069; GO:0014809; GO:0014819; GO:0014894; GO:0014904; GO:0016010; GO:0017022; GO:0017166; GO:0021629; GO:0021987; GO:0030016; GO:0030018; GO:0030027; GO:0030036; GO:0030054; GO:0030055; GO:0030141; GO:0030154; GO:0030165; GO:0030175; GO:0030182; GO:0030424; GO:0030672; GO:0030864; GO:0031527; GO:0032991; GO:0033137; GO:0035994; GO:0042383; GO:0042391; GO:0042692; GO:0042995; GO:0043005; GO:0043025; GO:0043034; GO:0043043; GO:0043403; GO:0044306; GO:0044877; GO:0045121; GO:0045202; GO:0045211; GO:0045213; GO:0045665; GO:0045666; GO:0046716; GO:0048471; GO:0048666; GO:0048812; GO:0050998; GO:0051015; GO:0051647; GO:0051726; GO:0055001; GO:0060048; GO:0060314; GO:0060857; GO:0065003; GO:0070373; GO:0086001; GO:0090257; GO:0090287; GO:0097449; GO:0099572; GO:0099617; GO:1901385; GO:1902083; GO:2000651 7616 XM_044317093.1 11 253 0 145 551 P11530 4.15e-42 Dystrophin Rattus norvegicus (Rat) actin cytoskeleton organization [GO:0030036]; aging [GO:0007568]; cardiac muscle cell action potential [GO:0086001]; cardiac muscle contraction [GO:0060048]; cell differentiation [GO:0030154]; cerebral cortex development [GO:0021987]; establishment of blood-nerve barrier [GO:0008065]; establishment of glial blood-brain barrier [GO:0060857]; muscle cell cellular homeostasis [GO:0046716]; muscle cell development [GO:0055001]; muscle cell differentiation [GO:0042692]; muscle organ development [GO:0007517]; myotube cell development [GO:0014904]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of peptidyl-cysteine S-nitrosylation [GO:1902083]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; neuron development [GO:0048666]; neuron differentiation [GO:0030182]; neuron projection morphogenesis [GO:0048812]; neurotransmitter receptor metabolic process [GO:0045213]; nucleus localization [GO:0051647]; olfactory nerve structural organization [GO:0021629]; peptide biosynthetic process [GO:0043043]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neuron projection development [GO:0010976]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; protein localization [GO:0008104]; protein-containing complex assembly [GO:0065003]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell cycle [GO:0051726]; regulation of cellular response to growth factor stimulus [GO:0090287]; regulation of DNA-templated transcription [GO:0006355]; regulation of gene expression [GO:0010468]; regulation of heart rate [GO:0002027]; regulation of membrane potential [GO:0042391]; regulation of muscle system process [GO:0090257]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of skeletal muscle contraction [GO:0014819]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; regulation of voltage-gated calcium channel activity [GO:1901385]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; response to muscle stretch [GO:0035994]; response to water deprivation [GO:0009414]; skeletal muscle tissue development [GO:0007519]; skeletal muscle tissue regeneration [GO:0043403] GO:0001954; GO:0002027; GO:0002162; GO:0003779; GO:0005178; GO:0005521; GO:0005634; GO:0005741; GO:0005794; GO:0005840; GO:0005883; GO:0005886; GO:0006355; GO:0007517; GO:0007519; GO:0007568; GO:0008065; GO:0008104; GO:0008270; GO:0008284; GO:0008307; GO:0009414; GO:0009986; GO:0010468; GO:0010880; GO:0010881; GO:0010976; GO:0014069; GO:0014809; GO:0014819; GO:0014894; GO:0014904; GO:0016010; GO:0017022; GO:0017166; GO:0021629; GO:0021987; GO:0030016; GO:0030018; GO:0030027; GO:0030036; GO:0030054; GO:0030055; GO:0030141; GO:0030154; GO:0030165; GO:0030175; GO:0030182; GO:0030424; GO:0030672; GO:0030864; GO:0031527; GO:0032991; GO:0033137; GO:0035994; GO:0042383; GO:0042391; GO:0042692; GO:0042995; GO:0043005; GO:0043025; GO:0043034; GO:0043043; GO:0043403; GO:0044306; GO:0044877; GO:0045121; GO:0045202; GO:0045211; GO:0045213; GO:0045665; GO:0045666; GO:0046716; GO:0048471; GO:0048666; GO:0048812; GO:0050998; GO:0051015; GO:0051647; GO:0051726; GO:0055001; GO:0060048; GO:0060314; GO:0060857; GO:0065003; GO:0070373; GO:0086001; GO:0090257; GO:0090287; GO:0097449; GO:0099572; GO:0099617; GO:1901385; GO:1902083; GO:2000651 7617 XM_044312922.1 24 9 24 87 28 O09167 1e-32 60S ribosomal protein L21 Mus musculus (Mouse) cytoplasmic translation [GO:0002181] GO:0002181; GO:0003735; GO:0005737; GO:0005783; GO:0005829; GO:0005840; GO:0022625; GO:0022626; GO:0045202; GO:0098794 7618 XM_029339271.2 531 0 355 53 639 P53454 1.36e-43 D(5)-like dopamine receptor Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) regulation of biological quality [GO:0065008] GO:0004930; GO:0005886; GO:0065008 7619 XR_006396993.1 0 0 2 59 0 NA NA NA NA NA NA 7620 XR_006397326.1 16 89 0 99 0 NA NA NA NA NA NA 7621 XM_044311989.1 39 65 35 120 63 NA NA NA NA NA NA 7622 XM_044328428.1 547 298 200 412 314 Q9Z2X2 1.95e-65 26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin) Mus musculus (Mouse) apoptotic process [GO:0006915]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cell growth [GO:0030307]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; proteasome regulatory particle assembly [GO:0070682] GO:0000122; GO:0000502; GO:0005634; GO:0005737; GO:0005829; GO:0006915; GO:0007253; GO:0008540; GO:0030307; GO:0031398; GO:0032088; GO:0032436; GO:0043066; GO:0043409; GO:0043518; GO:0045111; GO:0045737; GO:0070682; GO:0090201 7623 XM_044307175.1 2117 1022 1172 2156 1424 Q15436 0 Protein transport protein Sec23A (hSec23A) (SEC23-related protein A) Homo sapiens (Human) COPII-coated vesicle cargo loading [GO:0090110]; intracellular protein transport [GO:0006886]; protein localization to plasma membrane [GO:0072659] GO:0000139; GO:0005096; GO:0005789; GO:0005829; GO:0006886; GO:0008270; GO:0012507; GO:0019898; GO:0030127; GO:0048471; GO:0070971; GO:0072659; GO:0090110 7624 XM_044323424.1 12 8 15 60 122 NA NA NA NA NA NA 7625 XM_044312612.1 328 218 187 135 347 Q8NEZ2 2.55e-24 Vacuolar protein sorting-associated protein 37A (hVps37A) (ESCRT-I complex subunit VPS37A) (Hepatocellular carcinoma-related protein 1) Homo sapiens (Human) macroautophagy [GO:0016236]; membrane fission [GO:0090148]; multivesicular body assembly [GO:0036258]; protein targeting to membrane [GO:0006612]; protein targeting to vacuole [GO:0006623]; protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; viral budding via host ESCRT complex [GO:0039702] GO:0000813; GO:0005654; GO:0005813; GO:0005829; GO:0006612; GO:0006623; GO:0010008; GO:0016236; GO:0031902; GO:0036258; GO:0039702; GO:0043162; GO:0043231; GO:0043328; GO:0090148 7626 XM_044318633.1 6 0 0 0 0 NA NA NA NA NA NA 7627 XR_006394925.1 0 0 6 0 0 NA NA NA NA NA NA 7628 XR_006397560.1 16 52 0 49 6 NA NA NA NA NA NA 7629 XM_044319525.1 75 3 56 46 69 NA NA NA NA NA NA 7630 XM_029353657.2 0 0 15 0 0 P25931 1.56e-23 RYamide receptor (Neuropeptide Y-like receptor) (NPY-R) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218] GO:0001653; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0016020 7631 XM_029353965.2 41 0 28 48 0 Q8TCF1 8.48e-46 AN1-type zinc finger protein 1 (Zinc finger AN1-type-containing protein 1) Homo sapiens (Human) cellular response to arsenite ion [GO:1903843]; positive regulation of intracellular protein transport [GO:0090316]; stress granule disassembly [GO:0035617] GO:0005737; GO:0008270; GO:0010494; GO:0035617; GO:0070628; GO:0090316; GO:1903843 7632 XR_006396195.1 197 59 72 140 48 NA NA NA NA NA NA 7633 XM_044313475.1 0 0 0 0 9 NA NA NA NA NA NA 7634 XM_029357922.2 0 56 8 90 43 NA NA NA NA NA NA 7635 XR_006397665.1 215 100 336 187 333 NA NA NA NA NA NA 7636 XR_006391702.1 64 32 34 117 252 E7FAM5 4.71e-41 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 7637 XM_029345105.2 0 9 6 34 113 Q9DBW0 4.37e-155 Cytochrome P450 4V2 (Docosahexaenoic acid omega-hydroxylase CYP4V2) (EC 1.14.14.79) (Long-chain fatty acid omega-monooxygenase) (EC 1.14.14.80) Mus musculus (Mouse) fatty acid omega-oxidation [GO:0010430] GO:0005506; GO:0005789; GO:0010430; GO:0020037; GO:0102033 7638 XM_029336004.2 791 50 508 458 656 O94443 1.13e-63 Uncharacterized exonuclease C637.09 (EC 3.1.-.-) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; tRNA 3'-trailer cleavage, exonucleolytic [GO:0034415]; U5 snRNA 3'-end processing [GO:0034476] GO:0000175; GO:0000467; GO:0003676; GO:0004527; GO:0005634; GO:0034415; GO:0034476 7639 XM_029340948.2 826 563 457 934 816 G3UZ78 2.05e-125 Androglobin (Calpain-7-like protein) Mus musculus (Mouse) cell differentiation [GO:0030154]; proteolysis [GO:0006508]; spermatogenesis [GO:0007283] GO:0004198; GO:0006508; GO:0007283; GO:0019825; GO:0020037; GO:0030154; GO:0036126; GO:0097225; GO:0097227 7640 XM_029340948.2 826 563 457 934 816 G3UZ78 6.13e-64 Androglobin (Calpain-7-like protein) Mus musculus (Mouse) cell differentiation [GO:0030154]; proteolysis [GO:0006508]; spermatogenesis [GO:0007283] GO:0004198; GO:0006508; GO:0007283; GO:0019825; GO:0020037; GO:0030154; GO:0036126; GO:0097225; GO:0097227 7641 XM_029323568.2 1744 2125 668 2200 1101 Q4V8X0 2.19e-48 Transmembrane protein adipocyte-associated 1 homolog (Integral membrane protein GPR175) Danio rerio (Zebrafish) (Brachydanio rerio) G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0005886; GO:0007186 7642 XM_029338974.2 191 227 209 418 672 Q6P4Y6 2.26e-55 Insulin receptor substrate 1 (IRS-1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009] GO:0005158; GO:0005159; GO:0005634; GO:0005737; GO:0008286; GO:0042169; GO:0043231; GO:0043548; GO:0048009 7643 XR_003824089.2 42 29 63 11 103 NA NA NA NA NA NA 7644 XM_044325693.1 1 7 16 20 18 NA NA NA NA NA NA 7645 XR_003825228.2 4 9 14 23 0 NA NA NA NA NA NA 7646 XM_029334454.2 3372 2073 3009 4121 4786 Q9GLM4 3.81e-110 Tensin-1 (EC 3.1.3.-) Bos taurus (Bovine) fibroblast migration [GO:0010761] GO:0003779; GO:0004721; GO:0005737; GO:0005856; GO:0005925; GO:0009986; GO:0010761; GO:0046872 7647 XM_029334454.2 3372 2073 3009 4121 4786 Q9GLM4 7.18e-67 Tensin-1 (EC 3.1.3.-) Bos taurus (Bovine) fibroblast migration [GO:0010761] GO:0003779; GO:0004721; GO:0005737; GO:0005856; GO:0005925; GO:0009986; GO:0010761; GO:0046872 7648 XM_044322812.1 906 50 688 652 560 Q13591 3.2e-70 Semaphorin-5A (Semaphorin-F) (Sema F) Homo sapiens (Human) axon extension [GO:0048675]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell-cell signaling [GO:0007267]; diencephalon development [GO:0021536]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of cell adhesion [GO:0007162]; negative regulation of endothelial cell apoptotic process [GO:2000352]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; positive chemotaxis [GO:0050918]; positive regulation of actin filament depolymerization [GO:0030836]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein kinase B signaling [GO:0051897]; semaphorin-plexin signaling pathway [GO:0071526]; signal clustering [GO:1990256] GO:0001755; GO:0001938; GO:0002043; GO:0005886; GO:0007155; GO:0007162; GO:0007267; GO:0007399; GO:0007411; GO:0007413; GO:0016020; GO:0021536; GO:0030215; GO:0030335; GO:0030836; GO:0035373; GO:0043395; GO:0045499; GO:0045545; GO:0045766; GO:0048675; GO:0048842; GO:0048843; GO:0050918; GO:0051897; GO:0060326; GO:0070062; GO:0071526; GO:0090263; GO:1990256; GO:2000352; GO:2001028 7649 XM_029324107.2 46 10 9 3 0 NA NA NA NA NA NA 7650 XM_029337560.2 7 0 0 0 3 NA NA NA NA NA NA 7651 XM_029350846.2 164 81 233 464 231 NA NA NA NA NA NA 7652 XM_044322238.1 0 0 0 11 0 NA NA NA NA NA NA 7653 XM_044310854.1 315 66 75 140 149 NA NA NA NA NA NA 7654 XM_044312298.1 226 116 89 103 89 P37111 9.23e-25 Aminoacylase-1 (ACY-1) (EC 3.5.1.14) (N-acyl-L-amino-acid amidohydrolase) Sus scrofa (Pig) amino acid metabolic process [GO:0006520] GO:0004046; GO:0005737; GO:0006520; GO:0042802; GO:0046872; GO:0070062 7655 XM_029353150.2 146 254 87 498 235 NA NA NA NA NA NA 7656 XM_029331579.2 6 0 0 23 12 NA NA NA NA NA NA 7657 XR_006397300.1 45 14 56 25 68 NA NA NA NA NA NA 7658 XM_029327058.2 0 0 105 0 0 Q8R4K8 0 Pappalysin-1 (EC 3.4.24.79) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase) (Pregnancy-associated plasma protein A) (PAPP-A) Mus musculus (Mouse) cell surface receptor signaling pathway [GO:0007166]; female pregnancy [GO:0007565]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to dexamethasone [GO:0071548]; response to follicle-stimulating hormone [GO:0032354] GO:0004175; GO:0004222; GO:0005576; GO:0005615; GO:0006508; GO:0007166; GO:0007565; GO:0008237; GO:0030163; GO:0032354; GO:0046872; GO:0071548 7659 XM_044318663.1 0 0 0 200 0 O75899 9.73e-72 Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51) (HG20) Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway [GO:0007186]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; neuron-glial cell signaling [GO:0150099]; synaptic transmission, GABAergic [GO:0051932] GO:0004888; GO:0004965; GO:0005737; GO:0005886; GO:0007186; GO:0007193; GO:0007194; GO:0007214; GO:0007268; GO:0038039; GO:0043005; GO:0045211; GO:0046982; GO:0051932; GO:0150099; GO:1902710; GO:1902712 7660 XM_029347960.2 573 559 384 650 485 O18806 1.94e-27 Coagulation factor VIII (Procoagulant component) Canis lupus familiaris (Dog) (Canis familiaris) acute-phase response [GO:0006953]; blood coagulation [GO:0007596] GO:0005507; GO:0005615; GO:0006953; GO:0007596; GO:0016491 7661 XR_006396282.1 49 77 0 24 88 NA NA NA NA NA NA 7662 XR_006392184.1 0 0 0 33 0 NA NA NA NA NA NA 7663 XM_029340825.2 766 699 346 1565 807 Q3MHN0 3.18e-107 Proteasome subunit beta type-6 (EC 3.4.25.1) Bos taurus (Bovine) proteasomal protein catabolic process [GO:0010498] GO:0004175; GO:0004298; GO:0005654; GO:0005829; GO:0005839; GO:0010498; GO:0019774 7664 XM_029344827.2 2975 1842 1568 3032 2471 Q5T5U3 4.06e-98 Rho GTPase-activating protein 21 (Rho GTPase-activating protein 10) (Rho-type GTPase-activating protein 21) Homo sapiens (Human) establishment of Golgi localization [GO:0051683]; Golgi localization [GO:0051645]; Golgi organization [GO:0007030]; maintenance of Golgi location [GO:0051684]; organelle transport along microtubule [GO:0072384]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] GO:0000139; GO:0005096; GO:0005794; GO:0005829; GO:0005886; GO:0007030; GO:0007165; GO:0015629; GO:0030054; GO:0030659; GO:0051056; GO:0051645; GO:0051683; GO:0051684; GO:0070161; GO:0072384 7665 XM_029344827.2 2975 1842 1568 3032 2471 Q5T5U3 2.14e-28 Rho GTPase-activating protein 21 (Rho GTPase-activating protein 10) (Rho-type GTPase-activating protein 21) Homo sapiens (Human) establishment of Golgi localization [GO:0051683]; Golgi localization [GO:0051645]; Golgi organization [GO:0007030]; maintenance of Golgi location [GO:0051684]; organelle transport along microtubule [GO:0072384]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] GO:0000139; GO:0005096; GO:0005794; GO:0005829; GO:0005886; GO:0007030; GO:0007165; GO:0015629; GO:0030054; GO:0030659; GO:0051056; GO:0051645; GO:0051683; GO:0051684; GO:0070161; GO:0072384 7666 XM_044319441.1 7 1 36 106 39 P20825 3.2e-71 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 7667 XM_044323474.1 512 143 324 222 560 A4IFW2 0 Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) Danio rerio (Zebrafish) (Brachydanio rerio) peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; sensory neuron axon guidance [GO:0097374]; synaptic membrane adhesion [GO:0099560] GO:0004725; GO:0006470; GO:0008201; GO:0016020; GO:0035335; GO:0097374; GO:0099560 7668 XM_044323474.1 512 143 324 222 560 A4IFW2 3.39e-55 Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) Danio rerio (Zebrafish) (Brachydanio rerio) peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; sensory neuron axon guidance [GO:0097374]; synaptic membrane adhesion [GO:0099560] GO:0004725; GO:0006470; GO:0008201; GO:0016020; GO:0035335; GO:0097374; GO:0099560 7669 XM_044323474.1 512 143 324 222 560 A4IFW2 1.67e-54 Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) Danio rerio (Zebrafish) (Brachydanio rerio) peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; sensory neuron axon guidance [GO:0097374]; synaptic membrane adhesion [GO:0099560] GO:0004725; GO:0006470; GO:0008201; GO:0016020; GO:0035335; GO:0097374; GO:0099560 7670 XM_044323474.1 512 143 324 222 560 A4IFW2 5.35e-53 Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) Danio rerio (Zebrafish) (Brachydanio rerio) peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; sensory neuron axon guidance [GO:0097374]; synaptic membrane adhesion [GO:0099560] GO:0004725; GO:0006470; GO:0008201; GO:0016020; GO:0035335; GO:0097374; GO:0099560 7671 XM_044323474.1 512 143 324 222 560 A4IFW2 1.02e-32 Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) Danio rerio (Zebrafish) (Brachydanio rerio) peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; sensory neuron axon guidance [GO:0097374]; synaptic membrane adhesion [GO:0099560] GO:0004725; GO:0006470; GO:0008201; GO:0016020; GO:0035335; GO:0097374; GO:0099560 7672 XM_029340669.2 98 106 0 58 0 O14795 0 Protein unc-13 homolog B (Munc13-2) (munc13) Homo sapiens (Human) acrosomal vesicle exocytosis [GO:0060478]; cellular response to glucose stimulus [GO:0071333]; chemical synaptic transmission [GO:0007268]; dense core granule priming [GO:0061789]; neuromuscular junction development [GO:0007528]; neuronal dense core vesicle exocytosis [GO:0099011]; positive regulation of apoptotic process [GO:0043065]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of protein secretion [GO:0050714]; positive regulation of synaptic vesicle priming [GO:0010808]; presynaptic dense core vesicle exocytosis [GO:0099525]; synaptic transmission, glutamatergic [GO:0035249]; synaptic vesicle docking [GO:0016081]; synaptic vesicle maturation [GO:0016188]; synaptic vesicle priming [GO:0016082] GO:0005509; GO:0005516; GO:0005543; GO:0005794; GO:0005829; GO:0005886; GO:0007268; GO:0007528; GO:0010808; GO:0016020; GO:0016081; GO:0016082; GO:0016188; GO:0017075; GO:0019992; GO:0030672; GO:0030742; GO:0031267; GO:0031594; GO:0035249; GO:0042734; GO:0043065; GO:0043195; GO:0048786; GO:0050714; GO:0060478; GO:0061789; GO:0071333; GO:0097151; GO:0098831; GO:0099011; GO:0099525 7673 XR_006395796.1 139 225 305 254 150 NA NA NA NA NA NA 7674 XM_029351004.2 7 1 8 5 7 Q5SVZ6 1.12e-47 Zinc finger MYM-type protein 1 Homo sapiens (Human) NA GO:0005634; GO:0008270; GO:0046983 7675 XM_044309493.1 731 376 585 622 691 NA NA NA NA NA NA 7676 XM_044307258.1 16356 19145 11240 25271 17633 Q8BXJ2 8.71e-30 Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132) Mus musculus (Mouse) cellular response to progesterone stimulus [GO:0071393]; histone deacetylation [GO:0016575]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; progesterone receptor signaling pathway [GO:0050847]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000118; GO:0001223; GO:0001650; GO:0003677; GO:0003713; GO:0003714; GO:0005634; GO:0005654; GO:0005667; GO:0005829; GO:0006357; GO:0016575; GO:0030374; GO:0033142; GO:0045892; GO:0045893; GO:0045944; GO:0046872; GO:0050847; GO:0071393 7677 XM_029352906.2 3693 2179 2404 2262 3440 Q8VIJ6 1.84e-82 Splicing factor, proline- and glutamine-rich (DNA-binding p52/p100 complex, 100 kDa subunit) (Polypyrimidine tract-binding protein-associated-splicing factor) (PSF) (PTB-associated-splicing factor) Mus musculus (Mouse) activation of innate immune response [GO:0002218]; alternative mRNA splicing, via spliceosome [GO:0000380]; cellular response to DNA damage stimulus [GO:0006974]; chromosome organization [GO:0051276]; dendritic transport of messenger ribonucleoprotein complex [GO:0098963]; double-strand break repair via homologous recombination [GO:0000724]; histone H3 deacetylation [GO:0070932]; innate immune response [GO:0045087]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of sister chromatid cohesion [GO:0045876]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell cycle [GO:0051726]; regulation of circadian rhythm [GO:0042752]; regulation of DNA-templated transcription [GO:0006355]; rhythmic process [GO:0048511] GO:0000122; GO:0000380; GO:0000724; GO:0000785; GO:0000976; GO:0002218; GO:0003677; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0006355; GO:0006974; GO:0016363; GO:0016607; GO:0032839; GO:0042382; GO:0042752; GO:0042754; GO:0042803; GO:0042826; GO:0045087; GO:0045876; GO:0045892; GO:0045944; GO:0048511; GO:0051276; GO:0051726; GO:0070932; GO:0090575; GO:0098963; GO:1902177 7678 XM_029345999.2 832 374 537 715 814 P53804 1e-41 E3 ubiquitin-protein ligase TTC3 (EC 2.3.2.27) (Protein DCRR1) (RING finger protein 105) (RING-type E3 ubiquitin transferase TTC3) (TPR repeat protein D) (Tetratricopeptide repeat protein 3) (TPR repeat protein 3) Homo sapiens (Human) protein K48-linked ubiquitination [GO:0070936]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004842; GO:0005634; GO:0005654; GO:0005730; GO:0005794; GO:0005829; GO:0006511; GO:0046872; GO:0070936 7679 XM_029348803.2 73 45 61 523 160 NA NA NA NA NA NA 7680 XM_044314737.1 1739 94 1862 246 8285 NA NA NA NA NA NA 7681 XM_029356359.2 1886 2264 720 1464 1101 P26630 8.45e-91 Paired box protein Pax-6 (Pax[Zf-a]) Danio rerio (Zebrafish) (Brachydanio rerio) anatomical structure development [GO:0048856]; anterior/posterior pattern specification [GO:0009952]; epithalamus development [GO:0021538]; forebrain development [GO:0030900]; habenula development [GO:0021986]; hindbrain development [GO:0030902]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression [GO:0010468]; regulation of transcription by RNA polymerase II [GO:0006357]; retinal cone cell differentiation [GO:0042670]; retinal rod cell differentiation [GO:0060221] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0008284; GO:0009952; GO:0010468; GO:0021538; GO:0021986; GO:0030900; GO:0030902; GO:0042670; GO:0043565; GO:0045944; GO:0048856; GO:0060221 7682 XM_044310298.1 102 75 22 438 46 Q9NR20 3.77e-86 Dual specificity tyrosine-phosphorylation-regulated kinase 4 (EC 2.7.12.1) Homo sapiens (Human) peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107] GO:0004674; GO:0004712; GO:0004713; GO:0005524; GO:0005634; GO:0005737; GO:0005856; GO:0018105; GO:0018107; GO:0043231; GO:0046872; GO:0106310 7683 XR_006396758.1 17 0 29 6 110 NA NA NA NA NA NA 7684 XM_044320774.1 74 32 61 61 103 B8V7S0 3.25e-30 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 7685 XM_044320774.1 74 32 61 61 103 B8V7S0 2.31e-22 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 7686 XM_044315924.1 158 5 175 142 1240 NA NA NA NA NA NA 7687 XM_029349458.2 22 0 22 0 3 NA NA NA NA NA NA 7688 XM_044308545.1 0 0 22 21 47 NA NA NA NA NA NA 7689 XR_006397139.1 10 3 0 0 0 NA NA NA NA NA NA 7690 XM_044319200.1 733 467 369 817 921 B3EWZ3 6.9e-87 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 7691 XM_044319200.1 733 467 369 817 921 B3EWZ3 1.91e-86 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 7692 XM_044319200.1 733 467 369 817 921 B3EWZ3 1.21e-83 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 7693 XM_044319200.1 733 467 369 817 921 B3EWZ3 5.33e-75 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 7694 XM_044319200.1 733 467 369 817 921 B3EWZ3 6.62e-71 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 7695 XM_044319200.1 733 467 369 817 921 B3EWZ3 1.73e-67 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 7696 XM_044324824.1 7 0 0 0 0 NA NA NA NA NA NA 7697 XM_044313404.1 2 0 0 0 14 Q96AY4 7.05e-71 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7698 XM_044313404.1 2 0 0 0 14 Q96AY4 1.22e-68 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7699 XM_044313404.1 2 0 0 0 14 Q96AY4 5.7e-65 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7700 XM_044313404.1 2 0 0 0 14 Q96AY4 1.39e-61 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7701 XM_044313404.1 2 0 0 0 14 Q96AY4 7.06e-61 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7702 XM_044313404.1 2 0 0 0 14 Q96AY4 8.2e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7703 XM_044313404.1 2 0 0 0 14 Q96AY4 2.02e-52 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7704 XM_044313404.1 2 0 0 0 14 Q96AY4 3.13e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7705 XM_029348590.2 1589 2643 2124 2610 1889 Q9GRC0 1.14e-65 Serine/threonine-protein kinase mos (EC 2.7.11.1) (Oocyte maturation factor mos) Patiria pectinifera (Starfish) (Asterina pectinifera) female gamete generation [GO:0007292]; female meiosis II [GO:0007147]; negative regulation of mitotic cell cycle [GO:0045930]; protein phosphorylation [GO:0006468] GO:0004709; GO:0005524; GO:0006468; GO:0007147; GO:0007292; GO:0045930; GO:0106310 7706 XM_044310493.1 46 21 33 17 45 NA NA NA NA NA NA 7707 XM_029341490.2 89 24 30 45 82 Q8C206 5.34e-31 G-protein coupled receptor 157 Mus musculus (Mouse) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; circadian behavior [GO:0048512]; G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; radial glial cell differentiation [GO:0060019] GO:0004930; GO:0005886; GO:0007166; GO:0007186; GO:0007189; GO:0048512; GO:0051482; GO:0060019; GO:0060170 7708 XR_006392776.1 0 0 3 0 8 NA NA NA NA NA NA 7709 XR_006391785.1 0 0 10 11 2 NA NA NA NA NA NA 7710 XM_044314599.1 0 0 9 0 0 NA NA NA NA NA NA 7711 XM_029355488.2 380 379 642 545 709 Q6GNV7 3.78e-85 Solute carrier family 49 member 4 homolog (Disrupted in renal carcinoma protein 2 homolog) Xenopus laevis (African clawed frog) NA GO:0005765; GO:0022857 7712 XM_044327719.1 29 0 37 0 49 NA NA NA NA NA NA 7713 XM_029350355.2 208 212 100 270 165 Q99JB7 1.26e-41 Protein amnionless [Cleaved into: Soluble protein amnionless] Mus musculus (Mouse) cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; Golgi to plasma membrane protein transport [GO:0043001]; protein localization [GO:0008104]; receptor-mediated endocytosis [GO:0006898]; renal protein absorption [GO:0097017] GO:0005102; GO:0005615; GO:0005905; GO:0006898; GO:0008104; GO:0009235; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0030139; GO:0031526; GO:0031528; GO:0032991; GO:0038024; GO:0043001; GO:0043235; GO:0045177; GO:0097017 7714 XM_029337733.2 15 19 19 15 30 A3KP59 2.81e-55 Ribosomal oxygenase 1 (Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66) (EC 1.14.11.-, EC 1.14.11.27) (Histone lysine demethylase NO66) Danio rerio (Zebrafish) (Brachydanio rerio) chromatin organization [GO:0006325]; histone H3-K36 demethylation [GO:0070544]; histone H3-K4 demethylation [GO:0034720]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of osteoblast differentiation [GO:0045668] GO:0005506; GO:0005634; GO:0005654; GO:0005730; GO:0006325; GO:0016706; GO:0032453; GO:0034647; GO:0034720; GO:0036139; GO:0045668; GO:0045892; GO:0051864; GO:0070544; GO:0140457; GO:0140680 7715 XM_044314703.1 47 156 92 117 141 NA NA NA NA NA NA 7716 XM_044327526.1 0 0 0 22 0 NA NA NA NA NA NA 7717 XM_029341637.2 10617 15510 6182 7895 6257 Q8R2E9 2.5e-141 ERO1-like protein beta (ERO1-L-beta) (EC 1.8.4.-) (Endoplasmic reticulum oxidoreductase beta) (Endoplasmic reticulum oxidoreductin-1-like protein B) (Oxidoreductin-1-L-beta) Mus musculus (Mouse) cell redox homeostasis [GO:0045454]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; extracellular matrix organization [GO:0030198]; glucose homeostasis [GO:0042593]; insulin processing [GO:0030070]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; protein folding in endoplasmic reticulum [GO:0034975]; protein maturation by protein folding [GO:0022417] GO:0005788; GO:0005789; GO:0006888; GO:0015035; GO:0015036; GO:0016020; GO:0016972; GO:0018401; GO:0022417; GO:0030070; GO:0030198; GO:0034975; GO:0042593; GO:0045454; GO:0071949 7718 XM_044315196.1 9 53 16 0 15 Q09575 5.37e-28 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 7719 XM_044329076.1 53 9 4 9 19 NA NA NA NA NA NA 7720 XM_044317480.1 0 0 0 75 0 Q13114 3.48e-99 TNF receptor-associated factor 3 (EC 2.3.2.27) (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein 1) (LAP1) (RING-type E3 ubiquitin transferase TRAF3) Homo sapiens (Human) apoptotic process [GO:0006915]; defense response to virus [GO:0051607]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of JNK cascade [GO:0046330]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of cytokine production [GO:0001817]; regulation of defense response to virus [GO:0050688]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of interferon-beta production [GO:0032648]; regulation of proteolysis [GO:0030162]; signal transduction [GO:0007165]; Toll signaling pathway [GO:0008063]; toll-like receptor signaling pathway [GO:0002224]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; type I interferon-mediated signaling pathway [GO:0060337] GO:0000151; GO:0001817; GO:0002224; GO:0004842; GO:0005164; GO:0005739; GO:0005768; GO:0005829; GO:0006915; GO:0007165; GO:0008063; GO:0008270; GO:0009898; GO:0019901; GO:0019903; GO:0030162; GO:0031625; GO:0031996; GO:0032088; GO:0032648; GO:0033209; GO:0035631; GO:0035666; GO:0042802; GO:0042981; GO:0043122; GO:0046330; GO:0050688; GO:0051607; GO:0060337; GO:0070534; GO:1902554 7721 XR_006396860.1 0 26 30 130 112 NA NA NA NA NA NA 7722 XR_006393601.1 0 0 0 8 0 NA NA NA NA NA NA 7723 XM_044316021.1 240 279 253 262 461 Q13443 8.59e-71 Disintegrin and metalloproteinase domain-containing protein 9 (ADAM 9) (EC 3.4.24.-) (Cellular disintegrin-related protein) (Meltrin-gamma) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) Homo sapiens (Human) amyloid precursor protein catabolic process [GO:0042987]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell migration [GO:0016477]; cell-cell adhesion mediated by integrin [GO:0033631]; cell-matrix adhesion [GO:0007160]; cellular response to lipopolysaccharide [GO:0071222]; integrin-mediated signaling pathway [GO:0007229]; keratinocyte differentiation [GO:0030216]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; monocyte activation [GO:0042117]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of macrophage fusion [GO:0034241]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of protein secretion [GO:0050714]; protein processing [GO:0016485]; response to calcium ion [GO:0051592]; response to glucocorticoid [GO:0051384]; response to hydrogen peroxide [GO:0042542]; response to manganese ion [GO:0010042]; response to tumor necrosis factor [GO:0034612]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0004222; GO:0005080; GO:0005178; GO:0005518; GO:0005615; GO:0005925; GO:0006509; GO:0007155; GO:0007160; GO:0007179; GO:0007229; GO:0008237; GO:0009897; GO:0009986; GO:0010042; GO:0016477; GO:0016485; GO:0017124; GO:0030216; GO:0030335; GO:0031293; GO:0033627; GO:0033630; GO:0033631; GO:0034241; GO:0034612; GO:0042117; GO:0042542; GO:0042987; GO:0043236; GO:0043406; GO:0046872; GO:0050714; GO:0051044; GO:0051384; GO:0051549; GO:0051592; GO:0070062; GO:0071222; GO:1902945 7724 XM_029336275.2 181 46 149 172 388 NA NA NA NA NA NA 7725 XM_029356162.2 265 378 259 525 428 H9D1R1 3.47e-45 Thioredoxin domain-containing protein 12 (EC 1.8.4.2) Epinephelus coioides (Orange-spotted grouper) (Epinephelus nebulosus) defense response to virus [GO:0051607] GO:0005788; GO:0009055; GO:0019153; GO:0051607 7726 XM_029356162.2 265 378 259 525 428 H9D1R1 7.17e-37 Thioredoxin domain-containing protein 12 (EC 1.8.4.2) Epinephelus coioides (Orange-spotted grouper) (Epinephelus nebulosus) defense response to virus [GO:0051607] GO:0005788; GO:0009055; GO:0019153; GO:0051607 7727 XM_029356162.2 265 378 259 525 428 H9D1R1 9.03e-36 Thioredoxin domain-containing protein 12 (EC 1.8.4.2) Epinephelus coioides (Orange-spotted grouper) (Epinephelus nebulosus) defense response to virus [GO:0051607] GO:0005788; GO:0009055; GO:0019153; GO:0051607 7728 XM_029356162.2 265 378 259 525 428 H9D1R1 1.23e-33 Thioredoxin domain-containing protein 12 (EC 1.8.4.2) Epinephelus coioides (Orange-spotted grouper) (Epinephelus nebulosus) defense response to virus [GO:0051607] GO:0005788; GO:0009055; GO:0019153; GO:0051607 7729 XM_029356162.2 265 378 259 525 428 H9D1R1 4.52e-32 Thioredoxin domain-containing protein 12 (EC 1.8.4.2) Epinephelus coioides (Orange-spotted grouper) (Epinephelus nebulosus) defense response to virus [GO:0051607] GO:0005788; GO:0009055; GO:0019153; GO:0051607 7730 XM_029356162.2 265 378 259 525 428 H9D1R1 5.36e-30 Thioredoxin domain-containing protein 12 (EC 1.8.4.2) Epinephelus coioides (Orange-spotted grouper) (Epinephelus nebulosus) defense response to virus [GO:0051607] GO:0005788; GO:0009055; GO:0019153; GO:0051607 7731 XM_029356162.2 265 378 259 525 428 H9D1R1 1.9e-28 Thioredoxin domain-containing protein 12 (EC 1.8.4.2) Epinephelus coioides (Orange-spotted grouper) (Epinephelus nebulosus) defense response to virus [GO:0051607] GO:0005788; GO:0009055; GO:0019153; GO:0051607 7732 XR_006393218.1 13 0 12 136 12 O09167 2.15e-32 60S ribosomal protein L21 Mus musculus (Mouse) cytoplasmic translation [GO:0002181] GO:0002181; GO:0003735; GO:0005737; GO:0005783; GO:0005829; GO:0005840; GO:0022625; GO:0022626; GO:0045202; GO:0098794 7733 XM_029349522.2 1264 1461 843 1733 1002 NA NA NA NA NA NA 7734 XR_006397385.1 13 0 15 9 5 NA NA NA NA NA NA 7735 XM_044326596.1 32 13 32 51 73 Q96RW7 2.11e-71 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 7736 XM_044326596.1 32 13 32 51 73 Q96RW7 2.32e-64 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 7737 XM_044326596.1 32 13 32 51 73 Q96RW7 9.86e-61 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 7738 XM_044326596.1 32 13 32 51 73 Q96RW7 1.26e-57 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 7739 XM_044326596.1 32 13 32 51 73 Q96RW7 4.45e-56 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 7740 XM_044326596.1 32 13 32 51 73 Q96RW7 7.52e-53 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 7741 XM_044326596.1 32 13 32 51 73 Q96RW7 5.77e-45 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 7742 XM_044326906.1 16 28 70 3 169 NA NA NA NA NA NA 7743 XM_044311901.1 30 120 21 77 132 Q95SX7 6.58e-27 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 7744 XR_006395323.1 16 3 32 10 75 NA NA NA NA NA NA 7745 XR_006392481.1 122 145 56 175 154 NA NA NA NA NA NA 7746 XM_029356809.2 0 563 949 555 0 NA NA NA NA NA NA 7747 XM_029328458.2 641 503 454 725 887 Q14684 1.94e-51 Ribosomal RNA processing protein 1 homolog B (RRP1-like protein B) Homo sapiens (Human) apoptotic process [GO:0006915]; cellular response to virus [GO:0098586]; mRNA processing [GO:0006397]; negative regulation of GTPase activity [GO:0034260]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of apoptotic process [GO:0043065]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]; rRNA processing [GO:0006364] GO:0000791; GO:0000792; GO:0001652; GO:0003713; GO:0003723; GO:0005634; GO:0005654; GO:0005694; GO:0005730; GO:0005829; GO:0006364; GO:0006397; GO:0006915; GO:0008380; GO:0030687; GO:0030688; GO:0034260; GO:0043065; GO:0043484; GO:0043923; GO:0045944; GO:0098586 7748 XR_006394873.1 0 0 9 0 49 NA NA NA NA NA NA 7749 XM_029358581.2 4167 4515 4309 4102 5168 Q4R4P4 2.13e-87 Fatty acid 2-hydroxylase (EC 1.14.18.-) (Fatty acid alpha-hydroxylase) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) ceramide biosynthetic process [GO:0046513]; establishment of skin barrier [GO:0061436]; fatty acid biosynthetic process [GO:0006633]; galactosylceramide biosynthetic process [GO:0006682]; glucosylceramide biosynthetic process [GO:0006679]; plasma membrane raft organization [GO:0044857] GO:0005506; GO:0005789; GO:0006633; GO:0006679; GO:0006682; GO:0016020; GO:0020037; GO:0044857; GO:0046513; GO:0061436; GO:0080132 7750 XM_044316883.1 1 46 26 126 46 NA NA NA NA NA NA 7751 XM_044325191.1 10 0 0 8 2 NA NA NA NA NA NA 7752 XM_044308987.1 671 372 156 309 295 Q60HG9 0 Carnitine O-palmitoyltransferase 2, mitochondrial (EC 2.3.1.21) (Carnitine palmitoyltransferase II) (CPT II) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) carnitine metabolic process [GO:0009437]; fatty acid beta-oxidation [GO:0006635]; long-chain fatty acid metabolic process [GO:0001676] GO:0001676; GO:0004095; GO:0005743; GO:0006635; GO:0008458; GO:0009437; GO:0016746 7753 XR_006397396.1 44 39 39 41 41 NA NA NA NA NA NA 7754 XM_029348558.2 1914 359 712 2298 891 Q9Z139 1.79e-124 Inactive tyrosine-protein kinase transmembrane receptor ROR1 (mROR1) (Neurotrophic tyrosine kinase, receptor-related 1) Mus musculus (Mouse) astrocyte development [GO:0014002]; inner ear development [GO:0048839]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of kinase activity [GO:0033674]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; sensory perception of sound [GO:0007605] GO:0001725; GO:0004714; GO:0005524; GO:0005737; GO:0005886; GO:0007605; GO:0009986; GO:0010976; GO:0014002; GO:0014068; GO:0017147; GO:0033674; GO:0042813; GO:0043123; GO:0043235; GO:0043679; GO:0048839; GO:0051092 7755 XM_044307135.1 905 1515 265 510 830 NA NA NA NA NA NA 7756 XM_044307096.1 0 14 6 0 0 Q91VS8 2.65e-42 FERM, ARHGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR) (FERM, RhoGEF and pleckstrin domain-containing protein 2) Mus musculus (Mouse) actin cytoskeleton reorganization [GO:0031532]; cell adhesion [GO:0007155]; hair cycle process [GO:0022405]; neuron remodeling [GO:0016322]; osteoclast differentiation [GO:0030316]; podosome assembly [GO:0071800]; Rac protein signal transduction [GO:0016601]; regulation of integrin activation [GO:0033623]; semaphorin-plexin signaling pathway [GO:0071526] GO:0005085; GO:0005737; GO:0005829; GO:0005856; GO:0007155; GO:0008092; GO:0016322; GO:0016601; GO:0022405; GO:0030316; GO:0031532; GO:0033623; GO:0071526; GO:0071800 7757 XM_044323287.1 11 4 80 17 40 Q05360 1.98e-146 Protein white Lucilia cuprina (Green bottle fly) (Australian sheep blowfly) NA GO:0005524; GO:0016020; GO:0016887; GO:0031409; GO:0140359 7758 XM_044328693.1 64 0 0 0 16 O09118 0 Netrin-1 Mus musculus (Mouse) animal organ morphogenesis [GO:0009887]; anterior/posterior axon guidance [GO:0033564]; apoptotic process [GO:0006915]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; B cell mediated immunity [GO:0019724]; B cell proliferation [GO:0042100]; Cdc42 protein signal transduction [GO:0032488]; cell population proliferation [GO:0008283]; cell-cell adhesion [GO:0098609]; chemorepulsion of axon [GO:0061643]; dendrite development [GO:0016358]; glial cell proliferation [GO:0014009]; inner ear morphogenesis [GO:0042472]; mammary gland development [GO:0030879]; mammary gland duct morphogenesis [GO:0060603]; motor neuron axon guidance [GO:0008045]; motor neuron migration [GO:0097475]; negative regulation of axon extension [GO:0030517]; neuron migration [GO:0001764]; nuclear migration [GO:0007097]; positive regulation of axon extension [GO:0045773]; positive regulation of cell motility [GO:2000147]; positive regulation of glial cell proliferation [GO:0060252]; Ras protein signal transduction [GO:0007265]; regulation of cell migration [GO:0030334]; regulation of glial cell migration [GO:1903975]; regulation of synapse assembly [GO:0051963]; substrate-dependent cell migration, cell extension [GO:0006930]; T cell mediated immunity [GO:0002456]; tissue development [GO:0009888] GO:0001764; GO:0002456; GO:0005125; GO:0005576; GO:0005604; GO:0005654; GO:0005737; GO:0005829; GO:0006915; GO:0006930; GO:0007097; GO:0007265; GO:0007409; GO:0007411; GO:0008045; GO:0008283; GO:0009887; GO:0009888; GO:0014009; GO:0015629; GO:0016358; GO:0019724; GO:0030334; GO:0030517; GO:0030879; GO:0031012; GO:0032488; GO:0033564; GO:0042100; GO:0042472; GO:0045773; GO:0051963; GO:0060252; GO:0060603; GO:0061643; GO:0062023; GO:0071944; GO:0097475; GO:0098609; GO:1903975; GO:2000147 7759 XR_006396911.1 16 0 8 0 0 NA NA NA NA NA NA 7760 XM_044307490.1 5 15 15 1 0 P70490 2.93e-28 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 7761 XM_044307490.1 5 15 15 1 0 P70490 6.86e-22 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 7762 XR_006397855.1 39 12 60 23 47 NA NA NA NA NA NA 7763 XM_029335105.2 0 0 146 569 584 NA NA NA NA NA NA 7764 XM_029331637.2 1334 936 781 1455 1536 O00410 0 Importin-5 (Imp5) (Importin subunit beta-3) (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5) Homo sapiens (Human) cellular response to amino acid stimulus [GO:0071230]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of protein import into nucleus [GO:0042307]; protein import into nucleus [GO:0006606]; ribosomal protein import into nucleus [GO:0006610] GO:0003723; GO:0005095; GO:0005634; GO:0005643; GO:0005730; GO:0005737; GO:0006606; GO:0006607; GO:0006610; GO:0008139; GO:0016020; GO:0031267; GO:0042307; GO:0045736; GO:0061608; GO:0071230 7765 XM_029337232.2 211 384 139 385 374 NA NA NA NA NA NA 7766 XR_006394613.1 45 37 5 41 27 NA NA NA NA NA NA 7767 XM_029327865.2 8 7 0 7 1 NA NA NA NA NA NA 7768 XM_044318813.1 75 67 45 31 85 B3EWY9 8.77e-32 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 7769 XM_044311546.1 0 2 0 0 43 NA NA NA NA NA NA 7770 XM_044322646.1 56 22 30 0 70 NA NA NA NA NA NA 7771 XM_029326604.2 28 27 64 28 76 NA NA NA NA NA NA 7772 XM_044311053.1 40 43 38 52 25 P16157 3.88e-85 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 7773 XM_044311053.1 40 43 38 52 25 P16157 1.76e-76 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 7774 XM_044311053.1 40 43 38 52 25 P16157 6.06e-74 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 7775 XM_044311053.1 40 43 38 52 25 P16157 2.72e-71 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 7776 XM_044311053.1 40 43 38 52 25 P16157 2.94e-68 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 7777 XM_044311053.1 40 43 38 52 25 P16157 5.47e-64 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 7778 XM_029337373.2 154 75 86 175 167 A3KPW7 4.79e-54 Protein prenyltransferase alpha subunit repeat-containing protein 1 Danio rerio (Zebrafish) (Brachydanio rerio) protein prenylation [GO:0018342] GO:0005737; GO:0008318; GO:0018342 7779 XM_044323227.1 0 654 611 6 222 Q91VW5 8.05e-24 Golgin subfamily A member 4 (tGolgin-1) Mus musculus (Mouse) Golgi to plasma membrane protein transport [GO:0043001]; Golgi vesicle transport [GO:0048193]; positive regulation of axon extension [GO:0045773] GO:0000139; GO:0005654; GO:0005737; GO:0005794; GO:0031267; GO:0043001; GO:0045773; GO:0048193; GO:0051020 7780 XM_029331158.2 537 790 165 707 807 Q9NRK6 0 ATP-binding cassette sub-family B member 10, mitochondrial (ABC-mitochondrial erythroid protein) (ABC-me protein) (ATP-binding cassette transporter 10) (ABC transporter 10 protein) (Mitochondrial ATP-binding cassette 2) (M-ABC2) Homo sapiens (Human) erythrocyte development [GO:0048821]; heme biosynthetic process [GO:0006783]; mitochondrial transport [GO:0006839]; mitochondrial unfolded protein response [GO:0034514]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of heme biosynthetic process [GO:0070455]; positive regulation of hemoglobin biosynthetic process [GO:0046985] GO:0005524; GO:0005739; GO:0005743; GO:0006783; GO:0006839; GO:0016887; GO:0031966; GO:0034514; GO:0042803; GO:0045648; GO:0046985; GO:0048821; GO:0070455; GO:0140359 7781 XM_029328805.2 1437 1008 837 1311 1395 P50429 1.71e-159 Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S) Mus musculus (Mouse) anterior head development [GO:0097065]; autophagy [GO:0006914]; central nervous system development [GO:0007417]; chondroitin sulfate catabolic process [GO:0030207]; colon epithelial cell migration [GO:0061580]; dermatan sulfate catabolic process [GO:0030209]; positive regulation of neuron projection development [GO:0010976]; regulation of epithelial cell migration [GO:0010632]; response to estrogen [GO:0043627]; response to methylmercury [GO:0051597]; response to nutrient [GO:0007584]; response to pH [GO:0009268] GO:0003943; GO:0004065; GO:0005739; GO:0005764; GO:0005791; GO:0005794; GO:0006914; GO:0007417; GO:0007584; GO:0008484; GO:0009268; GO:0009986; GO:0010632; GO:0010976; GO:0030207; GO:0030209; GO:0043627; GO:0043890; GO:0046872; GO:0051597; GO:0061580; GO:0097065 7782 XM_044314364.1 470 222 456 723 656 Q6ZUG5 1.21e-98 Uncharacterized protein FLJ43738 Homo sapiens (Human) NA NA 7783 XM_029337549.2 1520 1707 1063 1534 1629 P61754 4.59e-59 Transcription factor SOX-9 Pongo pygmaeus (Bornean orangutan) cAMP-mediated signaling [GO:0019933]; cartilage condensation [GO:0001502]; cartilage development [GO:0051216]; cell fate specification [GO:0001708]; cellular response to BMP stimulus [GO:0071773]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to heparin [GO:0071504]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; chondrocyte differentiation [GO:0002062]; chondrocyte differentiation involved in endochondral bone morphogenesis [GO:0003413]; chondrocyte hypertrophy [GO:0003415]; chromatin remodeling [GO:0006338]; cochlea morphogenesis [GO:0090103]; endocardial cushion morphogenesis [GO:0003203]; epidermal growth factor receptor signaling pathway [GO:0007173]; epithelial cell proliferation involved in prostatic bud elongation [GO:0060517]; epithelial to mesenchymal transition [GO:0001837]; ERK1 and ERK2 cascade [GO:0070371]; growth plate cartilage chondrocyte growth [GO:0003430]; hair follicle development [GO:0001942]; heart valve development [GO:0003170]; heart valve morphogenesis [GO:0003179]; intestinal epithelial structure maintenance [GO:0060729]; male germ-line sex determination [GO:0019100]; male gonad development [GO:0008584]; metanephric nephron tubule formation [GO:0072289]; morphogenesis of a branching epithelium [GO:0061138]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of chondrocyte differentiation [GO:0032331]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fatty acid oxidation [GO:0046322]; negative regulation of immune system process [GO:0002683]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of ossification [GO:0030279]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of photoreceptor cell differentiation [GO:0046533]; neural crest cell fate specification [GO:0014036]; nucleosome assembly [GO:0006334]; otic vesicle formation [GO:0030916]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cartilage development [GO:0061036]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of epithelial cell differentiation [GO:0030858]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of gene expression [GO:0010628]; positive regulation of kidney development [GO:0090184]; positive regulation of male gonad development [GO:2000020]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of mesenchymal stem cell differentiation [GO:2000741]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein kinase B signaling [GO:0043491]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of cartilage development [GO:0061035]; regulation of cell cycle process [GO:0010564]; regulation of cell population proliferation [GO:0042127]; regulation of cell proliferation involved in tissue homeostasis [GO:0060784]; renal vesicle induction [GO:0072034]; response to fatty acid [GO:0070542]; retina development in camera-type eye [GO:0060041]; retinal rod cell differentiation [GO:0060221]; Sertoli cell differentiation [GO:0060008]; signal transduction [GO:0007165]; skeletal system development [GO:0001501]; somatic stem cell population maintenance [GO:0035019]; spermatogenesis [GO:0007283]; tissue homeostasis [GO:0001894] GO:0000978; GO:0000981; GO:0000987; GO:0001228; GO:0001501; GO:0001502; GO:0001708; GO:0001837; GO:0001894; GO:0001934; GO:0001942; GO:0002053; GO:0002062; GO:0002683; GO:0003170; GO:0003179; GO:0003203; GO:0003413; GO:0003415; GO:0003430; GO:0003677; GO:0003682; GO:0003700; GO:0005634; GO:0006334; GO:0006338; GO:0007165; GO:0007173; GO:0007283; GO:0008284; GO:0008584; GO:0010564; GO:0010628; GO:0010634; GO:0014036; GO:0014068; GO:0019100; GO:0019933; GO:0030279; GO:0030858; GO:0030916; GO:0032331; GO:0032332; GO:0032991; GO:0035019; GO:0042127; GO:0042981; GO:0043066; GO:0043491; GO:0043565; GO:0045662; GO:0045668; GO:0045892; GO:0045944; GO:0046322; GO:0046533; GO:0050679; GO:0050680; GO:0051216; GO:0060008; GO:0060041; GO:0060221; GO:0060517; GO:0060729; GO:0060784; GO:0061035; GO:0061036; GO:0061138; GO:0065003; GO:0070168; GO:0070371; GO:0070542; GO:0071260; GO:0071364; GO:0071504; GO:0071560; GO:0071773; GO:0072034; GO:0072289; GO:0090090; GO:0090103; GO:0090184; GO:0090190; GO:2000020; GO:2000741 7784 XM_029358683.2 972 0 456 461 363 P83038 0 Histone deacetylase 4 (HD4) (EC 3.5.1.98) Gallus gallus (Chicken) B cell activation [GO:0042113]; B cell differentiation [GO:0030183]; chromatin organization [GO:0006325]; histone deacetylation [GO:0016575]; histone H4 deacetylation [GO:0070933]; inflammatory response [GO:0006954]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of striated muscle tissue development [GO:0045843]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399] GO:0000118; GO:0000122; GO:0004407; GO:0005737; GO:0006325; GO:0006954; GO:0007399; GO:0016575; GO:0030183; GO:0042113; GO:0045843; GO:0045892; GO:0046872; GO:0070933; GO:0140297 7785 XM_029336822.2 231 136 146 232 81 Q5VVW2 0 GTPase-activating Rap/Ran-GAP domain-like protein 3 Homo sapiens (Human) activation of GTPase activity [GO:0090630]; regulation of small GTPase mediated signal transduction [GO:0051056] GO:0005096; GO:0005737; GO:0051056; GO:0090630 7786 XM_044323560.1 1243 980 429 1057 1048 NA NA NA NA NA NA 7787 XM_029342201.2 214 272 107 483 360 Q5ZIC8 6e-154 Importin-13 (Imp13) Gallus gallus (Chicken) protein import into nucleus [GO:0006606] GO:0005634; GO:0005737; GO:0006606 7788 XM_044314559.1 14 225 282 182 267 NA NA NA NA NA NA 7789 XM_029329041.2 474 241 352 228 453 O95801 3.23e-83 Tetratricopeptide repeat protein 4 (TPR repeat protein 4) Homo sapiens (Human) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; protein folding [GO:0006457] GO:0005634; GO:0005654; GO:0005737; GO:0006457; GO:0030544; GO:0045087; GO:0051607; GO:0051879 7790 XM_029330296.2 1366 1291 1373 1757 947 Q1RMP0 1.42e-36 DNA-directed RNA polymerase I subunit RPA12 (DNA-directed RNA polymerase I subunit H) Bos taurus (Bovine) mRNA cleavage [GO:0006379]; termination of RNA polymerase I transcription [GO:0006363] GO:0003676; GO:0003899; GO:0005654; GO:0005736; GO:0006363; GO:0006379; GO:0008270 7791 XM_044317218.1 559 190 129 851 720 NA NA NA NA NA NA 7792 XM_029335988.2 1157 984 481 1215 863 Q502L2 1.05e-74 Serine/threonine-protein phosphatase PGAM5, mitochondrial (EC 3.1.3.16) (Phosphoglycerate mutase family member 5) Danio rerio (Zebrafish) (Brachydanio rerio) peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of mitochondrial fission [GO:0090141]; programmed cell death [GO:0012501] GO:0004722; GO:0005739; GO:0005741; GO:0012501; GO:0017018; GO:0035970; GO:0090141 7793 XM_044307452.1 7 0 0 0 0 Q99315 8.26e-68 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 7794 XM_044324218.1 95 99 156 172 228 Q8K2J9 9.4e-67 BTB/POZ domain-containing protein 6 Mus musculus (Mouse) neurogenesis [GO:0022008] GO:0005829; GO:0022008 7795 XM_029326949.2 56 11 25 17 91 NA NA NA NA NA NA 7796 XM_044307316.1 6 4 6 21 11 NA NA NA NA NA NA 7797 XM_029347984.2 259 0 354 187 179 NA NA NA NA NA NA 7798 XM_029357160.2 0 9 9 15 50 NA NA NA NA NA NA 7799 XM_044311235.1 68 18 34 130 62 NA NA NA NA NA NA 7800 XM_029348973.2 14 0 0 6 3 NA NA NA NA NA NA 7801 XM_029344692.2 809 257 369 535 693 Q9VKA4 2.42e-63 Probable G-protein coupled receptor CG31760 Drosophila melanogaster (Fruit fly) NA GO:0004930; GO:0005886 7802 XR_006398171.1 14 1 19 5 47 NA NA NA NA NA NA 7803 XM_029351851.2 1459 1158 966 1767 1083 Q9M0X9 4e-130 4-coumarate--CoA ligase-like 7 (EC 6.2.1.-) (4-coumarate--CoA ligase isoform 6) (At4CL6) Arabidopsis thaliana (Mouse-ear cress) fatty acid biosynthetic process [GO:0006633]; jasmonic acid biosynthetic process [GO:0009695]; oxylipin biosynthetic process [GO:0031408] GO:0004321; GO:0005524; GO:0005777; GO:0006633; GO:0009695; GO:0016405; GO:0031408 7804 XM_029351851.2 1459 1158 966 1767 1083 Q9M0X9 4.99e-121 4-coumarate--CoA ligase-like 7 (EC 6.2.1.-) (4-coumarate--CoA ligase isoform 6) (At4CL6) Arabidopsis thaliana (Mouse-ear cress) fatty acid biosynthetic process [GO:0006633]; jasmonic acid biosynthetic process [GO:0009695]; oxylipin biosynthetic process [GO:0031408] GO:0004321; GO:0005524; GO:0005777; GO:0006633; GO:0009695; GO:0016405; GO:0031408 7805 XM_029324022.2 0 133 0 7 63 Q8VIJ8 5.13e-151 GATOR complex protein NPRL3 (Nitrogen permease regulator 3-like protein) Mus musculus (Mouse) aorta morphogenesis [GO:0035909]; cardiac muscle tissue development [GO:0048738]; cellular response to amino acid starvation [GO:0034198]; negative regulation of TOR signaling [GO:0032007]; negative regulation of TORC1 signaling [GO:1904262]; positive regulation of autophagy [GO:0010508]; roof of mouth development [GO:0060021]; TORC1 signaling [GO:0038202]; ventricular septum development [GO:0003281] GO:0003281; GO:0005096; GO:0005765; GO:0010508; GO:0032007; GO:0034198; GO:0035909; GO:0038202; GO:0048738; GO:0060021; GO:1904262; GO:1990130 7806 XM_044323048.1 0 336 204 36 192 NA NA NA NA NA NA 7807 XM_029342161.2 1416 1557 559 1640 915 Q6DF07 2.19e-44 Programmed cell death protein 10 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; apoptotic process [GO:0006915] GO:0000139; GO:0001525; GO:0005886; GO:0006915 7808 XM_029355325.2 61 112 161 1359 0 G8HTB6 1.36e-28 ZP domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 7809 XM_029336196.2 494 271 348 433 532 Q7SXP2 0 NEDD8-activating enzyme E1 regulatory subunit (APP-BP1) (Amyloid protein-binding protein 1) Danio rerio (Zebrafish) (Brachydanio rerio) protein modification by small protein conjugation [GO:0032446]; protein neddylation [GO:0045116] GO:0005737; GO:0019781; GO:0032446; GO:0045116 7810 XM_029329011.2 4 0 77 0 0 Q3ZBG9 1.05e-68 Phospholipid scramblase 2 (PL scramblase 2) (Ca(2+)-dependent phospholipid scramblase 2) Bos taurus (Bovine) plasma membrane phospholipid scrambling [GO:0017121] GO:0005886; GO:0017121; GO:0017128; GO:0046872 7811 XM_029347127.2 20 0 23 5 32 P41968 1.44e-24 Melanocortin receptor 3 (MC3-R) Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; circadian regulation of gene expression [GO:0032922]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; homoiothermy [GO:0042309]; locomotor rhythm [GO:0045475]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; regulation of blood pressure [GO:0008217]; regulation of feeding behavior [GO:0060259]; regulation of heart rate [GO:0002027]; regulation of metabolic process [GO:0019222]; sodium ion homeostasis [GO:0055078] GO:0002027; GO:0004930; GO:0004977; GO:0004980; GO:0005737; GO:0005886; GO:0007187; GO:0007189; GO:0007200; GO:0008217; GO:0017046; GO:0019222; GO:0032922; GO:0042309; GO:0042923; GO:0045475; GO:0055078; GO:0060259 7812 XM_029337241.2 1072 223 163 307 801 F5H4B4 3.8e-42 Protein FAM227A Homo sapiens (Human) NA NA 7813 XM_044314103.1 112 17 120 142 170 Q9WTK3 1.33e-94 Glycosylphosphatidylinositol anchor attachment 1 protein (GPI anchor attachment protein 1) (GAA1 protein homolog) (mGAA1) Mus musculus (Mouse) attachment of GPI anchor to protein [GO:0016255]; GPI anchor biosynthetic process [GO:0006506]; protein-containing complex assembly [GO:0065003] GO:0003923; GO:0005739; GO:0005783; GO:0005813; GO:0005829; GO:0005886; GO:0006506; GO:0016020; GO:0016255; GO:0034235; GO:0042765; GO:0065003 7814 XM_029334416.2 0 0 202 160 352 Q6DKN2 2.95e-34 Homeobox protein OTX2-B (xOTX2-B) (Orthodenticle 2-B) (Orthodenticle-A-like protein B) Xenopus laevis (African clawed frog) NA GO:0000981; GO:0003677; GO:0005634 7815 XM_029345841.2 744 466 518 758 749 Q5U317 1.12e-31 Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1 protein) Rattus norvegicus (Rat) mRNA polyadenylation [GO:0006378]; pre-mRNA cleavage required for polyadenylation [GO:0098789] GO:0003723; GO:0005634; GO:0005847; GO:0006378; GO:0098789 7816 XR_006392447.1 1 0 3 6 0 NA NA NA NA NA NA 7817 XM_029342388.2 6 2 7 21 0 NA NA NA NA NA NA 7818 XM_029344431.2 2798 2206 1586 2074 2324 Q5F356 4.08e-123 Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha (EC 2.7.1.149) (1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha) (Diphosphoinositide kinase 2-alpha) (Phosphatidylinositol 5-phosphate 4-kinase type II alpha) (PI(5)P 4-kinase type II alpha) (PIP4KII-alpha) (PtdIns(5)P-4-kinase isoform 2-alpha) Gallus gallus (Chicken) 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process [GO:1902635]; autophagosome-lysosome fusion [GO:0061909]; phosphatidylinositol phosphate biosynthetic process [GO:0046854]; phosphorylation [GO:0016310]; regulation of autophagy [GO:0010506]; vesicle-mediated cholesterol transport [GO:0090119] GO:0005524; GO:0005634; GO:0005764; GO:0005829; GO:0005886; GO:0010506; GO:0016308; GO:0016309; GO:0016310; GO:0042803; GO:0046854; GO:0061909; GO:0090119; GO:1902635 7819 XM_044317962.1 0 0 17 0 8 Q09811 2.37e-21 ATP-dependent DNA helicase hus2/rqh1 (EC 3.6.4.12) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) cellular response to DNA damage stimulus [GO:0006974]; DNA double-strand break processing [GO:0000729]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724]; maintenance of rDNA [GO:0043007]; mitotic intra-S DNA damage checkpoint signaling [GO:0031573]; mitotic recombination-dependent replication fork processing [GO:1990426]; postreplication repair [GO:0006301]; recombinational repair [GO:0000725]; regulation of mitotic recombination-dependent replication fork processing [GO:1903221]; replication fork processing [GO:0031297]; resolution of mitotic recombination intermediates [GO:0071140]; UV-damage excision repair [GO:0070914] GO:0000228; GO:0000724; GO:0000725; GO:0000729; GO:0003677; GO:0005524; GO:0005634; GO:0005694; GO:0005730; GO:0005737; GO:0006268; GO:0006281; GO:0006301; GO:0006310; GO:0006974; GO:0009378; GO:0016887; GO:0031297; GO:0031422; GO:0031573; GO:0032508; GO:0035861; GO:0043007; GO:0043138; GO:0043596; GO:0070914; GO:0071140; GO:1903221; GO:1990426 7820 XM_044311718.1 100 147 216 85 402 NA NA NA NA NA NA 7821 XM_044307090.1 487 488 242 1102 438 Q8CEE7 5.26e-69 Retinol dehydrogenase 13 (EC 1.1.1.300) Mus musculus (Mouse) eye photoreceptor cell development [GO:0042462]; response to high light intensity [GO:0009644]; retina layer formation [GO:0010842]; retinal metabolic process [GO:0042574] GO:0005739; GO:0005743; GO:0009644; GO:0010842; GO:0042462; GO:0042574; GO:0052650 7822 XM_044318220.1 296 123 197 152 485 Q6GLL2 9.39e-61 Monoacylglycerol lipase abhd6-A (EC 3.1.1.23) (Abhydrolase domain-containing protein 6-A) Xenopus laevis (African clawed frog) acylglycerol catabolic process [GO:0046464]; lysobisphosphatidic acid metabolic process [GO:2001311]; monoacylglycerol catabolic process [GO:0052651] GO:0005765; GO:0016020; GO:0031902; GO:0031966; GO:0046464; GO:0047372; GO:0052651; GO:2001311 7823 XM_044317287.1 6 6 38 0 0 Q9Y394 4.18e-73 Dehydrogenase/reductase SDR family member 7 (EC 1.1.1.-) (Retinal short-chain dehydrogenase/reductase 4) (retSDR4) (Short chain dehydrogenase/reductase family 34C member 1) (Protein SDR34C1) Homo sapiens (Human) NA GO:0004090; GO:0005789; GO:0016020; GO:0016616; GO:0052650 7824 XM_044312136.1 0 3 0 15 0 NA NA NA NA NA NA 7825 XM_044318104.1 36 49 24 35 0 NA NA NA NA NA NA 7826 XR_006391782.1 2 20 4 140 44 NA NA NA NA NA NA 7827 XM_044327810.1 16 6 23 16 19 NA NA NA NA NA NA 7828 XM_044311646.1 0 30 0 0 0 F1NY98 8.94e-33 Cell adhesion molecule DSCAM (Down syndrome cell adhesion molecule homolog) Gallus gallus (Chicken) axon guidance [GO:0007411]; camera-type eye photoreceptor cell differentiation [GO:0060219]; dendrite morphogenesis [GO:0048813]; dendrite self-avoidance [GO:0070593]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; locomotory behavior [GO:0007626]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of phosphorylation [GO:0042327]; post-embryonic retina morphogenesis in camera-type eye [GO:0060060]; retina layer formation [GO:0010842]; synapse assembly [GO:0007416] GO:0005886; GO:0007156; GO:0007162; GO:0007411; GO:0007416; GO:0007626; GO:0010842; GO:0030425; GO:0030426; GO:0042327; GO:0043025; GO:0045202; GO:0048813; GO:0048842; GO:0060060; GO:0060219; GO:0070593; GO:1990782; GO:1990890 7829 XR_006396658.1 49 76 17 45 49 NA NA NA NA NA NA 7830 XM_029340806.2 19712 28421 18484 21821 8751 P10160 2.48e-69 Eukaryotic translation initiation factor 5A-1 (eIF-5A-1) (eIF-5A1) (Eukaryotic initiation factor 5A isoform 1) (eIF-5A) (eIF-4D) Oryctolagus cuniculus (Rabbit) positive regulation of translation [GO:0045727]; positive regulation of translational elongation [GO:0045901]; positive regulation of translational termination [GO:0045905] GO:0003723; GO:0003746; GO:0005634; GO:0005789; GO:0043022; GO:0045727; GO:0045901; GO:0045905 7831 XM_044307854.1 336 31 237 381 133 Q61554 5.01e-91 Fibrillin-1 [Cleaved into: Asprosin] Mus musculus (Mouse) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; kidney development [GO:0001822]; metanephros development [GO:0001656]; negative regulation of brown fat cell differentiation [GO:1903444]; negative regulation of insulin secretion [GO:0046676]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0001822; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0046676; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1903444; GO:1990314; GO:2001205 7832 XM_044307854.1 336 31 237 381 133 Q61554 2.04e-84 Fibrillin-1 [Cleaved into: Asprosin] Mus musculus (Mouse) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; kidney development [GO:0001822]; metanephros development [GO:0001656]; negative regulation of brown fat cell differentiation [GO:1903444]; negative regulation of insulin secretion [GO:0046676]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0001822; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0046676; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1903444; GO:1990314; GO:2001205 7833 XM_044307854.1 336 31 237 381 133 Q61554 3.62e-78 Fibrillin-1 [Cleaved into: Asprosin] Mus musculus (Mouse) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; kidney development [GO:0001822]; metanephros development [GO:0001656]; negative regulation of brown fat cell differentiation [GO:1903444]; negative regulation of insulin secretion [GO:0046676]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0001822; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0046676; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1903444; GO:1990314; GO:2001205 7834 XM_044307854.1 336 31 237 381 133 Q61554 4.31e-77 Fibrillin-1 [Cleaved into: Asprosin] Mus musculus (Mouse) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; kidney development [GO:0001822]; metanephros development [GO:0001656]; negative regulation of brown fat cell differentiation [GO:1903444]; negative regulation of insulin secretion [GO:0046676]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0001822; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0046676; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1903444; GO:1990314; GO:2001205 7835 XM_044307854.1 336 31 237 381 133 Q61554 3.89e-68 Fibrillin-1 [Cleaved into: Asprosin] Mus musculus (Mouse) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; kidney development [GO:0001822]; metanephros development [GO:0001656]; negative regulation of brown fat cell differentiation [GO:1903444]; negative regulation of insulin secretion [GO:0046676]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0001822; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0046676; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1903444; GO:1990314; GO:2001205 7836 XM_044307854.1 336 31 237 381 133 Q61554 1.32e-66 Fibrillin-1 [Cleaved into: Asprosin] Mus musculus (Mouse) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; kidney development [GO:0001822]; metanephros development [GO:0001656]; negative regulation of brown fat cell differentiation [GO:1903444]; negative regulation of insulin secretion [GO:0046676]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0001822; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0046676; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1903444; GO:1990314; GO:2001205 7837 XM_044307854.1 336 31 237 381 133 Q61554 8.73e-58 Fibrillin-1 [Cleaved into: Asprosin] Mus musculus (Mouse) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; kidney development [GO:0001822]; metanephros development [GO:0001656]; negative regulation of brown fat cell differentiation [GO:1903444]; negative regulation of insulin secretion [GO:0046676]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0001822; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0046676; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1903444; GO:1990314; GO:2001205 7838 XM_044307854.1 336 31 237 381 133 Q61554 1.49e-33 Fibrillin-1 [Cleaved into: Asprosin] Mus musculus (Mouse) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; kidney development [GO:0001822]; metanephros development [GO:0001656]; negative regulation of brown fat cell differentiation [GO:1903444]; negative regulation of insulin secretion [GO:0046676]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0001822; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0046676; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1903444; GO:1990314; GO:2001205 7839 XM_044308964.1 28 9 0 57 26 NA NA NA NA NA NA 7840 XM_029338180.2 74 13 0 75 30 NA NA NA NA NA NA 7841 XM_044310367.1 26 7 25 0 23 NA NA NA NA NA NA 7842 XR_003825168.2 62 0 0 39 71 NA NA NA NA NA NA 7843 XM_029356447.2 67 0 0 79 0 E2JA28 7.75e-39 Dapdiamide synthesis protein DdaC (EC 1.-.-.-) Enterobacter agglomerans (Erwinia herbicola) (Pantoea agglomerans) antibiotic biosynthetic process [GO:0017000] GO:0016491; GO:0017000 7844 XM_044309580.1 0 0 0 0 49 NA NA NA NA NA NA 7845 XM_044315901.1 11 3 0 9 2 NA NA NA NA NA NA 7846 XR_003828449.2 733 849 698 663 971 NA NA NA NA NA NA 7847 XM_044322675.1 1066 403 372 508 451 Q18297 1.41e-134 Transient receptor potential cation channel subfamily A member 1 homolog Caenorhabditis elegans response to stimulus [GO:0050896] GO:0005216; GO:0005886; GO:0043025; GO:0050896; GO:0097730 7848 XM_044322675.1 1066 403 372 508 451 Q18297 4.99e-35 Transient receptor potential cation channel subfamily A member 1 homolog Caenorhabditis elegans response to stimulus [GO:0050896] GO:0005216; GO:0005886; GO:0043025; GO:0050896; GO:0097730 7849 XM_029349333.2 204 201 226 193 193 Q5BKT4 2.3e-91 Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase (EC 2.4.1.256) (Alpha-1,2-glucosyltransferase ALG10-A) (Alpha-2-glucosyltransferase ALG10-A) (Asparagine-linked glycosylation protein 10 homolog A) Homo sapiens (Human) dolichol-linked oligosaccharide biosynthetic process [GO:0006488]; protein N-linked glycosylation [GO:0006487] GO:0005783; GO:0005789; GO:0006487; GO:0006488; GO:0106073 7850 XM_044311196.1 0 423 332 782 190 Q5TJ56 4.82e-44 Formin-F (Diaphanous-related formin dia1) Dictyostelium discoideum (Social amoeba) 'de novo' actin filament nucleation [GO:0070060]; actin filament polymerization [GO:0030041]; positive phototaxis [GO:0046956] GO:0005522; GO:0015629; GO:0030041; GO:0031143; GO:0031267; GO:0046956; GO:0051015; GO:0070060 7851 XM_044317377.1 838 129 205 236 396 Q96AY4 2.71e-81 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7852 XM_044317377.1 838 129 205 236 396 Q96AY4 2.15e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7853 XM_044317377.1 838 129 205 236 396 Q96AY4 3.25e-70 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7854 XM_044317377.1 838 129 205 236 396 Q96AY4 1.28e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7855 XM_044317377.1 838 129 205 236 396 Q96AY4 2.69e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7856 XM_029355980.2 729 56 462 382 450 NA NA NA NA NA NA 7857 XM_044315523.1 30 10 0 0 0 NA NA NA NA NA NA 7858 XM_044311861.1 444 164 338 443 830 NA NA NA NA NA NA 7859 XR_003824505.2 101 111 68 0 0 NA NA NA NA NA NA 7860 XM_044309910.1 108 23 18 36 17 NA NA NA NA NA NA 7861 XM_044307522.1 0 0 1 8 2 NA NA NA NA NA NA 7862 XM_044313106.1 15 9 56 43 49 NA NA NA NA NA NA 7863 XM_029327457.2 48 13 23 27 21 NA NA NA NA NA NA 7864 XR_006391414.1 30 0 4 18 0 NA NA NA NA NA NA 7865 XR_006396783.1 51 444 732 274 193 NA NA NA NA NA NA 7866 XR_006398004.1 54 0 17 10 9 NA NA NA NA NA NA 7867 XM_044314386.1 14 15 51 8 124 NA NA NA NA NA NA 7868 XM_029355989.2 0 0 0 0 43 NA NA NA NA NA NA 7869 XM_029351587.2 408 441 224 592 705 Q9XT71 1.5e-103 Retinoid isomerohydrolase (EC 3.1.1.64) (All-trans-retinyl-palmitate hydrolase) (Lutein isomerase) (Meso-zeaxanthin isomerase) (EC 5.3.3.22) (Retinal pigment epithelium-specific 65 kDa protein) (Retinol isomerase) Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops) response to stimulus [GO:0050896]; retinoid metabolic process [GO:0001523]; visual perception [GO:0007601]; zeaxanthin biosynthetic process [GO:1901827] GO:0001523; GO:0001786; GO:0005789; GO:0005886; GO:0007601; GO:0016020; GO:0016702; GO:0016853; GO:0031210; GO:0046872; GO:0050896; GO:0052884; GO:0052885; GO:1901612; GO:1901827 7870 XM_044327046.1 316 849 220 319 163 NA NA NA NA NA NA 7871 XR_006395097.1 66 5 56 32 239 NA NA NA NA NA NA 7872 XM_044311494.1 10 0 0 2 32 NA NA NA NA NA NA 7873 XM_029348262.2 11127 11127 3232 6088 3884 Q8MIR4 3.8e-117 Bifunctional coenzyme A synthase (CoA synthase) (NBP) (POV-2) [Includes: Phosphopantetheine adenylyltransferase (EC 2.7.7.3) (Dephospho-CoA pyrophosphorylase) (Pantetheine-phosphate adenylyltransferase) (PPAT); Dephospho-CoA kinase (DPCK) (EC 2.7.1.24) (Dephosphocoenzyme A kinase) (DPCOAK)] Sus scrofa (Pig) coenzyme A biosynthetic process [GO:0015937]; phosphorylation [GO:0016310] GO:0004140; GO:0004595; GO:0005524; GO:0005759; GO:0015937; GO:0016310 7874 XM_029335912.2 72 64 87 283 322 NA NA NA NA NA NA 7875 XM_044326827.1 59 12 2 12 60 NA NA NA NA NA NA 7876 XM_029324584.2 1491 947 871 1351 952 Q0IIE6 3.47e-82 ELMO domain-containing protein 1 Bos taurus (Bovine) NA GO:0005096 7877 XM_029335901.2 30309 18531 15880 20236 22718 Q6P1M3 0 LLGL scribble cell polarity complex component 2 (HGL) (Lethal(2) giant larvae protein homolog 2) Homo sapiens (Human) cell division [GO:0051301]; cortical actin cytoskeleton organization [GO:0030866]; establishment of spindle orientation [GO:0051294]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; exocytosis [GO:0006887]; leucine transport [GO:0015820]; regulation of establishment or maintenance of cell polarity [GO:0032878]; regulation of Notch signaling pathway [GO:0008593]; regulation of protein secretion [GO:0050708] GO:0005096; GO:0005737; GO:0005829; GO:0005886; GO:0005912; GO:0006887; GO:0008593; GO:0015820; GO:0030165; GO:0030864; GO:0030866; GO:0032878; GO:0043231; GO:0045159; GO:0045197; GO:0050708; GO:0051294; GO:0051301 7878 XM_029339557.2 6456 12359 5335 6599 4284 NA NA NA NA NA NA 7879 XR_006391323.1 10 4 6 6 59 NA NA NA NA NA NA 7880 XM_044312252.1 0 2 5 0 8 NA NA NA NA NA NA 7881 XM_029355965.2 266 163 289 226 447 NA NA NA NA NA NA 7882 XM_044315539.1 1 2 3 37 3 NA NA NA NA NA NA 7883 XM_044325396.1 3125 2780 2475 4405 5069 Q28C74 1.4e-49 Leucine-rich PPR motif-containing protein, mitochondrial Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0003677; GO:0003723; GO:0005634; GO:0005739 7884 XM_029354352.2 65 53 27 71 80 Q9VUL9 6.06e-51 Glycoprotein 3-alpha-L-fucosyltransferase A (EC 2.4.1.214) (Core alpha-(1,3)-fucosyltransferase) Drosophila melanogaster (Fruit fly) fucosylation [GO:0036065]; N-glycan fucosylation [GO:0036071]; nervous system development [GO:0007399]; protein glycosylation [GO:0006486] GO:0005797; GO:0006486; GO:0007399; GO:0008417; GO:0018392; GO:0032580; GO:0036065; GO:0036071; GO:0046920 7885 XM_044317842.1 6 0 0 0 10 NA NA NA NA NA NA 7886 XM_044307781.1 16 25 44 361 147 NA NA NA NA NA NA 7887 XM_044312999.1 86 357 166 64 98 NA NA NA NA NA NA 7888 XM_044329224.1 348 308 69 272 70 NA NA NA NA NA NA 7889 XM_044306870.1 143 347 302 346 318 Q08431 1.22e-54 Lactadherin (Breast epithelial antigen BA46) (HMFG) (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (SED1) [Cleaved into: Lactadherin short form; Medin] Homo sapiens (Human) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005576; GO:0005615; GO:0005788; GO:0007155; GO:0007338; GO:0009897; GO:0016020; GO:0043277; GO:0062023; GO:0070062; GO:1903561 7890 XM_044316547.1 640 295 344 856 343 NA NA NA NA NA NA 7891 XM_029340933.2 352 107 197 151 37 Q5XI57 5.08e-107 Protein polyglycylase TTLL10 (EC 6.3.2.-) (Tubulin--tyrosine ligase-like protein 10) Rattus norvegicus (Rat) protein polyglycylation [GO:0018094] GO:0005524; GO:0005874; GO:0005929; GO:0005930; GO:0015630; GO:0018094; GO:0046872; GO:0070735; GO:0070737 7892 XM_044318781.1 444 834 412 662 644 NA NA NA NA NA NA 7893 XM_029345064.2 93 32 23 36 25 NA NA NA NA NA NA 7894 XM_044326171.1 8 0 15 0 35 NA NA NA NA NA NA 7895 XM_044310919.1 12 8 0 6 29 Q99315 8.84e-56 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 7896 XM_029338013.2 58 20 15 95 42 NA NA NA NA NA NA 7897 XM_029328660.2 241 105 66 191 123 Q8HYJ7 1.32e-45 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5 (EC 2.4.1.152) (3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT5) (EC 2.4.1.65) (Fucosyltransferase 5) (Fucosyltransferase V) (Fuc-TV) (FucT-V) (Galactoside 3-L-fucosyltransferase) Gorilla gorilla gorilla (Western lowland gorilla) ceramide metabolic process [GO:0006672]; fucosylation [GO:0036065]; oligosaccharide metabolic process [GO:0009311]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493] GO:0006487; GO:0006493; GO:0006672; GO:0009311; GO:0017060; GO:0017083; GO:0032580; GO:0036065; GO:0046920 7898 XM_044314172.1 0 0 0 12 0 NA NA NA NA NA NA 7899 XM_029332286.2 3738 4130 2678 2480 2119 P19984 6.08e-28 Profilin-2 (Basic profilin) (Profilin II) Acanthamoeba castellanii (Amoeba) NA GO:0003779; GO:0005737; GO:0005856 7900 XM_029353136.2 117 112 52 235 230 Q8K1T0 1.45e-42 Transmembrane protease serine 3 (EC 3.4.21.-) Mus musculus (Mouse) cellular sodium ion homeostasis [GO:0006883]; proteolysis [GO:0006508]; sensory perception of sound [GO:0007605] GO:0004252; GO:0005044; GO:0005783; GO:0005789; GO:0006508; GO:0006883; GO:0007605; GO:0017080; GO:0043025 7901 XM_029351398.2 53 37 16 0 0 A0A1L8F5J9 2.48e-51 Glutamate receptor ionotropic, NMDA 1 (GluN1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1) Xenopus laevis (African clawed frog) response to zinc ion [GO:0010043] GO:0004972; GO:0005886; GO:0010043; GO:0017146; GO:0045211; GO:0046872 7902 XM_029350765.2 55 7 38 30 59 Q9CZV8 1.25e-21 F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like) Mus musculus (Mouse) behavioral fear response [GO:0001662]; regulation of protein catabolic process at presynapse, modulating synaptic transmission [GO:0099575]; regulation of synaptic vesicle exocytosis [GO:2000300]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0001662; GO:0005737; GO:0019005; GO:0031146; GO:0045202; GO:0098685; GO:0098793; GO:0098978; GO:0099575; GO:2000300 7903 XM_044320703.1 6 0 10 0 0 NA NA NA NA NA NA 7904 XM_029324311.2 0 0 28 229 150 NA NA NA NA NA NA 7905 XR_006391823.1 3 5 4 1 20 NA NA NA NA NA NA 7906 XM_029336783.2 476 215 234 607 800 P02468 0 Laminin subunit gamma-1 (Laminin B2 chain) (Laminin-1 subunit gamma) (Laminin-10 subunit gamma) (Laminin-11 subunit gamma) (Laminin-2 subunit gamma) (Laminin-3 subunit gamma) (Laminin-4 subunit gamma) (Laminin-6 subunit gamma) (Laminin-7 subunit gamma) (Laminin-8 subunit gamma) (Laminin-9 subunit gamma) (S-laminin subunit gamma) (S-LAM gamma) Mus musculus (Mouse) animal organ morphogenesis [GO:0009887]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; chromatin organization [GO:0006325]; extracellular matrix disassembly [GO:0022617]; gene expression [GO:0010467]; hair cell differentiation [GO:0035315]; hair follicle cell proliferation [GO:0071335]; hair follicle morphogenesis [GO:0031069]; hemidesmosome assembly [GO:0031581]; neuron projection development [GO:0031175]; positive regulation of cell adhesion [GO:0045785]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of muscle cell differentiation [GO:0051149]; protein-containing complex assembly [GO:0065003]; regulation of basement membrane organization [GO:0110011]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]; tissue morphogenesis [GO:0048729] GO:0005201; GO:0005576; GO:0005604; GO:0005606; GO:0006325; GO:0007155; GO:0009887; GO:0009888; GO:0010467; GO:0016477; GO:0022617; GO:0031012; GO:0031069; GO:0031175; GO:0031581; GO:0031594; GO:0034446; GO:0035315; GO:0043083; GO:0043208; GO:0043259; GO:0045785; GO:0048729; GO:0051149; GO:0062023; GO:0065003; GO:0071335; GO:0098637; GO:0110011; GO:2001046 7907 XM_029348366.2 53 31 26 70 27 NA NA NA NA NA NA 7908 XM_029343307.2 257 158 87 202 231 Q497B2 7.96e-25 Transmembrane protein 45B Rattus norvegicus (Rat) innate immune response [GO:0045087] GO:0005765; GO:0005794; GO:0010008; GO:0045087 7909 XM_029327151.2 166 88 115 135 267 Q9VCA2 4.69e-77 Organic cation transporter protein Drosophila melanogaster (Fruit fly) apoptotic process [GO:0006915]; ion transport [GO:0006811] GO:0006811; GO:0006915; GO:0016020; GO:0022857 7910 XM_044311009.1 0 1 0 0 41 NA NA NA NA NA NA 7911 XM_029357045.2 121 171 93 179 132 NA NA NA NA NA NA 7912 XM_044321600.1 1276 2409 1250 1220 1739 Q6NYW6 1.08e-161 CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2) Danio rerio (Zebrafish) (Brachydanio rerio) cell division [GO:0051301]; establishment of mitotic spindle localization [GO:0040001]; exit from mitosis [GO:0010458]; Golgi organization [GO:0007030]; microtubule anchoring [GO:0034453]; microtubule cytoskeleton organization [GO:0000226]; microtubule nucleation [GO:0007020]; microtubule organizing center organization [GO:0031023]; mitotic spindle assembly [GO:0090307]; mitotic spindle organization [GO:0007052]; regulation of microtubule polymerization or depolymerization [GO:0031110]; regulation of microtubule-based process [GO:0032886] GO:0000226; GO:0000776; GO:0005794; GO:0005802; GO:0005815; GO:0005874; GO:0005876; GO:0005881; GO:0007020; GO:0007030; GO:0007052; GO:0008017; GO:0010458; GO:0031023; GO:0031110; GO:0031252; GO:0032587; GO:0032886; GO:0034453; GO:0040001; GO:0045180; GO:0051010; GO:0051301; GO:0072686; GO:0090307 7913 XM_044321600.1 1276 2409 1250 1220 1739 Q6NYW6 9.65e-44 CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2) Danio rerio (Zebrafish) (Brachydanio rerio) cell division [GO:0051301]; establishment of mitotic spindle localization [GO:0040001]; exit from mitosis [GO:0010458]; Golgi organization [GO:0007030]; microtubule anchoring [GO:0034453]; microtubule cytoskeleton organization [GO:0000226]; microtubule nucleation [GO:0007020]; microtubule organizing center organization [GO:0031023]; mitotic spindle assembly [GO:0090307]; mitotic spindle organization [GO:0007052]; regulation of microtubule polymerization or depolymerization [GO:0031110]; regulation of microtubule-based process [GO:0032886] GO:0000226; GO:0000776; GO:0005794; GO:0005802; GO:0005815; GO:0005874; GO:0005876; GO:0005881; GO:0007020; GO:0007030; GO:0007052; GO:0008017; GO:0010458; GO:0031023; GO:0031110; GO:0031252; GO:0032587; GO:0032886; GO:0034453; GO:0040001; GO:0045180; GO:0051010; GO:0051301; GO:0072686; GO:0090307 7914 XM_029333276.2 423 539 326 438 363 F1MNN4 1.11e-67 F-box/WD repeat-containing protein 7 (F-box and WD-40 domain-containing protein 7) Bos taurus (Bovine) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; lung development [GO:0030324]; negative regulation of gene expression [GO:0010629]; negative regulation of osteoclast development [GO:2001205]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; Notch signaling pathway [GO:0007219]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903378]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein destabilization [GO:0031648]; protein K63-linked ubiquitination [GO:0070534]; protein stabilization [GO:0050821]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of cell migration involved in sprouting angiogenesis [GO:0090049]; regulation of circadian rhythm [GO:0042752]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; sister chromatid cohesion [GO:0007062]; vasculogenesis [GO:0001570] GO:0001570; GO:0005654; GO:0005694; GO:0005730; GO:0005739; GO:0005783; GO:0006281; GO:0006886; GO:0006888; GO:0006890; GO:0006891; GO:0006974; GO:0007062; GO:0007219; GO:0010629; GO:0019005; GO:0030126; GO:0030324; GO:0030332; GO:0031146; GO:0031625; GO:0031648; GO:0042752; GO:0042802; GO:0045741; GO:0048471; GO:0050816; GO:0050821; GO:0051443; GO:0070374; GO:0070534; GO:0090049; GO:0097027; GO:1901800; GO:1903026; GO:1903146; GO:1903378; GO:1903955; GO:1990452; GO:1990756; GO:2000060; GO:2001205 7915 XM_029337960.2 95 132 85 25 80 NA NA NA NA NA NA 7916 XM_029332874.2 95 141 159 97 110 NA NA NA NA NA NA 7917 XM_044315887.1 19 0 17 0 46 NA NA NA NA NA NA 7918 XM_044318799.1 0 0 49 161 11 NA NA NA NA NA NA 7919 XM_044318967.1 68 109 37 177 0 NA NA NA NA NA NA 7920 XM_044317795.1 294 32 23 396 373 P36633 0 Amiloride-sensitive amine oxidase [copper-containing] (DAO) (Diamine oxidase) (EC 1.4.3.22) (Amiloride-binding protein 1) (Amine oxidase copper domain-containing protein 1) (Histaminase) Rattus norvegicus (Rat) amiloride transport [GO:0015898]; amine metabolic process [GO:0009308]; cellular response to azide [GO:0097185]; cellular response to copper ion [GO:0071280]; cellular response to copper ion starvation [GO:0035874]; cellular response to histamine [GO:0071420]; putrescine metabolic process [GO:0009445]; response to antibiotic [GO:0046677] GO:0005507; GO:0005509; GO:0005615; GO:0005886; GO:0005923; GO:0008131; GO:0008201; GO:0008270; GO:0009308; GO:0009445; GO:0015898; GO:0035874; GO:0042803; GO:0044877; GO:0046677; GO:0048038; GO:0052597; GO:0052598; GO:0052599; GO:0052600; GO:0070062; GO:0071280; GO:0071420; GO:0097159; GO:0097185 7921 XM_044313518.1 25 15 3 18 16 A0A0C2SRU0 8.26e-79 Decarboxylase iboD (EC 4.1.1.-) (Ibotenic acid biosynthesis cluster protein D) Amanita muscaria (strain Koide BX008) phospholipid biosynthetic process [GO:0008654] GO:0004609; GO:0008654 7922 XM_029345479.2 110 107 111 22 7 NA NA NA NA NA NA 7923 XM_044319870.1 3 0 5 16 11 NA NA NA NA NA NA 7924 XM_044322716.1 20 10 40 17 69 NA NA NA NA NA NA 7925 XM_029344239.2 2539 1702 896 4115 4197 Q9DC70 3.75e-98 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (EC 7.1.1.2) (Complex I-20kD) (CI-20kD) (NADH-ubiquinone oxidoreductase 20 kDa subunit) Mus musculus (Mouse) aerobic respiration [GO:0009060]; electron transport coupled proton transport [GO:0015990]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrial respiratory chain complex I assembly [GO:0032981]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776] GO:0002020; GO:0003954; GO:0005739; GO:0005743; GO:0005747; GO:0006120; GO:0008137; GO:0009060; GO:0015990; GO:0032981; GO:0042776; GO:0043005; GO:0043025; GO:0046872; GO:0048038; GO:0051539; GO:0097060 7926 XM_044307682.1 0 0 0 0 74 NA NA NA NA NA NA 7927 XM_029352257.2 0 0 0 0 8 Q4R3J0 1.39e-120 RNA 3'-terminal phosphate cyclase (RNA cyclase) (RNA-3'-phosphate cyclase) (EC 6.5.1.4) (RNA terminal phosphate cyclase domain-containing protein 1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) RNA processing [GO:0006396] GO:0003963; GO:0005524; GO:0005654; GO:0006396 7928 XM_029327839.2 652 362 98 76 403 Q4R630 1.37e-83 Kinetochore protein NDC80 homolog (Kinetochore protein Hec1) (Kinetochore-associated protein 2) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) attachment of mitotic spindle microtubules to kinetochore [GO:0051315]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; metaphase plate congression [GO:0051310]; mitotic spindle organization [GO:0007052]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267] GO:0000776; GO:0005634; GO:0007052; GO:0007059; GO:0031262; GO:0051301; GO:0051310; GO:0051315; GO:0090267; GO:0140483 7929 XM_029353240.2 3136 1635 445 1959 1683 NA NA NA NA NA NA 7930 XM_029335315.2 409 3 3 6 155 Q3US41 4.28e-133 Epithelial splicing regulatory protein 1 (RNA-binding motif protein 35A) (RNA-binding protein 35A) Mus musculus (Mouse) alternative mRNA splicing, via spliceosome [GO:0000380]; branching involved in salivary gland morphogenesis [GO:0060445]; epithelial cell proliferation [GO:0050673]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; positive regulation of epithelial cell proliferation [GO:0050679]; regulation of inner ear auditory receptor cell fate specification [GO:0042669]; regulation of RNA splicing [GO:0043484] GO:0000380; GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0016604; GO:0042669; GO:0043484; GO:0050673; GO:0050679; GO:0060441; GO:0060445; GO:1990904 7931 XR_003822973.2 0 20 0 0 0 NA NA NA NA NA NA 7932 XR_006395340.1 45 43 37 39 114 Q9M9E8 2.44e-25 Lysine-specific demethylase JMJ21 (EC 1.14.11.-) (F-box protein JMJ21) (Jumonji domain-containing protein 21) (AtJMJ21) (Protein JUMONJI 21) (Lysine-specific histone demethylase JMJ21) ([histone H3]-trimethyl-L-lysine monodemethylase JMJ21) Arabidopsis thaliana (Mouse-ear cress) NA GO:0005634; GO:0005737; GO:0016491; GO:0046872 7933 XR_006395340.1 45 43 37 39 114 Q9M9E8 2.44e-25 Lysine-specific demethylase JMJ21 (EC 1.14.11.-) (F-box protein JMJ21) (Jumonji domain-containing protein 21) (AtJMJ21) (Protein JUMONJI 21) (Lysine-specific histone demethylase JMJ21) ([histone H3]-trimethyl-L-lysine monodemethylase JMJ21) Arabidopsis thaliana (Mouse-ear cress) NA GO:0005634; GO:0005737; GO:0016491; GO:0046872 7934 XR_006396854.1 30 0 14 7 235 NA NA NA NA NA NA 7935 XM_029329286.2 1 0 0 0 29 P18130 1.61e-47 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) Bos taurus (Bovine) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of vasoconstriction [GO:0045907]; regulation of cardiac muscle contraction [GO:0055117] GO:0001996; GO:0004930; GO:0004937; GO:0005634; GO:0005737; GO:0005886; GO:0005901; GO:0007200; GO:0007204; GO:0007267; GO:0031965; GO:0043410; GO:0045907; GO:0046982; GO:0055117; GO:0071880 7936 XM_044313182.1 4 0 0 0 12 NA NA NA NA NA NA 7937 XM_044321401.1 236 26 113 202 213 NA NA NA NA NA NA 7938 XM_044324874.1 294 515 290 397 583 P07099 9.77e-126 Epoxide hydrolase 1 (EC 3.3.2.9) (Epoxide hydratase) (Microsomal epoxide hydrolase) (mEH) Homo sapiens (Human) arachidonic acid metabolic process [GO:0019369]; aromatic compound catabolic process [GO:0019439]; epoxide metabolic process [GO:0097176]; response to organic cyclic compound [GO:0014070]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805] GO:0004301; GO:0005789; GO:0006805; GO:0009636; GO:0014070; GO:0019369; GO:0019439; GO:0033961; GO:0097176 7939 XM_044312899.1 605 769 444 634 871 NA NA NA NA NA NA 7940 XM_044326836.1 50 1 33 6 101 NA NA NA NA NA NA 7941 XM_029348048.2 0 96 0 144 0 A8MU46 6.91e-26 Smoothelin-like protein 1 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; muscle organ morphogenesis [GO:0048644]; negative regulation of DNA-templated transcription [GO:0045892]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of vasoconstriction [GO:0045907]; response to activity [GO:0014823]; response to xenobiotic stimulus [GO:0009410]; vasoconstriction [GO:0042310] GO:0005516; GO:0005523; GO:0005634; GO:0005737; GO:0005815; GO:0008157; GO:0009410; GO:0014823; GO:0018105; GO:0030036; GO:0031430; GO:0031674; GO:0031941; GO:0042310; GO:0043292; GO:0043621; GO:0045892; GO:0045907; GO:0048644; GO:0051401; GO:0097718 7942 XM_044311569.1 135 151 31 89 54 Q6P5E4 0 UDP-glucose:glycoprotein glucosyltransferase 1 (UGT1) (EC 2.4.1.-) (UDP--Glc:glycoprotein glucosyltransferase) (UDP-glucose ceramide glucosyltransferase-like 1) Mus musculus (Mouse) ER-associated misfolded protein catabolic process [GO:0071712]; protein N-linked glycosylation via asparagine [GO:0018279] GO:0003980; GO:0005783; GO:0005788; GO:0005793; GO:0018279; GO:0032991; GO:0051082; GO:0071712 7943 XR_006398124.1 12 30 64 50 50 E9Q236 0 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 7944 XR_006398124.1 12 30 64 50 50 E9Q236 0 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 7945 XM_029331972.2 2118 838 1073 2895 2409 B8V7R6 4.19e-53 Collagen alpha chain Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005201; GO:0005576; GO:0005581 7946 XR_006393901.1 41 2 25 5 151 NA NA NA NA NA NA 7947 XM_029333533.2 106472 69795 53780 70121 21968 Q60803 1.85e-112 TNF receptor-associated factor 3 (EC 2.3.2.27) (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (RING-type E3 ubiquitin transferase TRAF3) Mus musculus (Mouse) apoptotic process [GO:0006915]; innate immune response [GO:0045087]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of JNK cascade [GO:0046330]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of cytokine production [GO:0001817]; regulation of defense response to virus [GO:0050688]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of interferon-beta production [GO:0032648]; regulation of proteolysis [GO:0030162]; Toll signaling pathway [GO:0008063]; toll-like receptor signaling pathway [GO:0002224]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0001817; GO:0002224; GO:0005164; GO:0005739; GO:0005768; GO:0006915; GO:0008063; GO:0008270; GO:0009898; GO:0016740; GO:0019901; GO:0019903; GO:0030162; GO:0031625; GO:0031996; GO:0032088; GO:0032648; GO:0033209; GO:0035631; GO:0042802; GO:0042981; GO:0043122; GO:0045087; GO:0046330; GO:0050688; GO:0070534 7948 XM_044313053.1 17 12 17 10 10 Q96AY4 1.11e-51 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7949 XM_044313053.1 17 12 17 10 10 Q96AY4 2.49e-50 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7950 XM_044313053.1 17 12 17 10 10 Q96AY4 2.49e-50 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7951 XM_044313053.1 17 12 17 10 10 Q96AY4 5.21e-50 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7952 XM_044313053.1 17 12 17 10 10 Q96AY4 1.83e-47 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7953 XM_044313053.1 17 12 17 10 10 Q96AY4 1.83e-47 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7954 XM_044313053.1 17 12 17 10 10 Q96AY4 1.11e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7955 XM_044313053.1 17 12 17 10 10 Q96AY4 1.11e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7956 XM_044313053.1 17 12 17 10 10 Q96AY4 8e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7957 XM_044313053.1 17 12 17 10 10 Q96AY4 8e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7958 XM_044313053.1 17 12 17 10 10 Q96AY4 2.62e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7959 XM_044313053.1 17 12 17 10 10 Q96AY4 2.62e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7960 XM_044313053.1 17 12 17 10 10 Q96AY4 1.5e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7961 XM_044313053.1 17 12 17 10 10 Q96AY4 1.85e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7962 XM_044313053.1 17 12 17 10 10 Q96AY4 1.85e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7963 XM_044313053.1 17 12 17 10 10 Q96AY4 3.73e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7964 XM_044313053.1 17 12 17 10 10 Q96AY4 1.89e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7965 XM_044313053.1 17 12 17 10 10 Q96AY4 1.89e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7966 XM_044313053.1 17 12 17 10 10 Q96AY4 7.43e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7967 XM_044313053.1 17 12 17 10 10 Q96AY4 2.27e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7968 XM_044313053.1 17 12 17 10 10 Q96AY4 4.77e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7969 XM_044313746.1 0 2 7 2 73 NA NA NA NA NA NA 7970 XM_044308141.1 690 913 437 441 430 P0CL18 2.29e-146 Eukaryotic translation initiation factor 2D (eIF2d) (Ligatin) Oryctolagus cuniculus (Rabbit) formation of translation preinitiation complex [GO:0001731]; IRES-dependent viral translational initiation [GO:0075522]; ribosome disassembly [GO:0032790] GO:0001731; GO:0003723; GO:0003743; GO:0016604; GO:0022627; GO:0032790; GO:0075522 7971 XM_044317848.1 3815 3846 2899 3847 4261 Q6NS15 6.63e-46 Mediator of RNA polymerase II transcription subunit 15 (Activator-recruited cofactor 105 kDa component) (ARC105) (xARC105) (Mediator complex subunit 15) Xenopus laevis (African clawed frog) positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0003712; GO:0005737; GO:0016592; GO:0045944 7972 XM_044314430.1 19 25 25 27 16 Q96AY4 5.72e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7973 XM_044314430.1 19 25 25 27 16 Q96AY4 2.49e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7974 XM_044314430.1 19 25 25 27 16 Q96AY4 1.37e-72 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7975 XM_044314430.1 19 25 25 27 16 Q96AY4 1.38e-71 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7976 XM_044314430.1 19 25 25 27 16 Q96AY4 2.78e-68 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7977 XM_044314430.1 19 25 25 27 16 Q96AY4 1.64e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7978 XM_044314430.1 19 25 25 27 16 Q96AY4 1.01e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7979 XM_044314430.1 19 25 25 27 16 Q96AY4 1.96e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7980 XM_029337688.2 23 50 0 0 36 NA NA NA NA NA NA 7981 XM_044320601.1 636 444 235 501 500 Q9Z2V5 7.8e-124 Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Histone deacetylase mHDA2) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-) Mus musculus (Mouse) aggresome assembly [GO:0070842]; axonal transport of mitochondrion [GO:0019896]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to misfolded protein [GO:0071218]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to topologically incorrect protein [GO:0035967]; cilium disassembly [GO:0061523]; collateral sprouting [GO:0048668]; dendritic spine morphogenesis [GO:0060997]; epigenetic regulation of gene expression [GO:0040029]; histone deacetylation [GO:0016575]; Hsp90 deacetylation [GO:0070846]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; mitochondrion localization [GO:0051646]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of protein-containing complex disassembly [GO:0043242]; negative regulation of proteolysis [GO:0045861]; negative regulation of transcription by RNA polymerase II [GO:0000122]; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:0061734]; peptidyl-lysine deacetylation [GO:0034983]; polyubiquitinated misfolded protein transport [GO:0070845]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of hydrogen peroxide-mediated programmed cell death [GO:1901300]; positive regulation of mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of tubulin deacetylation [GO:0090044]; protein deacetylation [GO:0006476]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; protein-containing complex disassembly [GO:0032984]; regulation of establishment of protein localization [GO:0070201]; regulation of fat cell differentiation [GO:0045598]; regulation of macroautophagy [GO:0016241]; regulation of mitochondrion organization [GO:0010821]; regulation of protein stability [GO:0031647]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]; response to dexamethasone [GO:0071548]; response to growth factor [GO:0070848]; response to immobilization stress [GO:0035902]; response to misfolded protein [GO:0051788]; tubulin deacetylation [GO:0090042]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] GO:0000118; GO:0000122; GO:0000209; GO:0000978; GO:0001222; GO:0001975; GO:0003779; GO:0004407; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0005829; GO:0005874; GO:0005875; GO:0005901; GO:0006476; GO:0006511; GO:0006515; GO:0006886; GO:0007026; GO:0008013; GO:0008017; GO:0008270; GO:0010634; GO:0010821; GO:0015630; GO:0016234; GO:0016235; GO:0016241; GO:0016575; GO:0019896; GO:0030424; GO:0030425; GO:0031252; GO:0031333; GO:0031593; GO:0031625; GO:0031647; GO:0031648; GO:0032418; GO:0032984; GO:0032991; GO:0033138; GO:0033558; GO:0034983; GO:0035902; GO:0035967; GO:0036064; GO:0040029; GO:0042826; GO:0042903; GO:0043005; GO:0043014; GO:0043025; GO:0043130; GO:0043162; GO:0043204; GO:0043242; GO:0045598; GO:0045861; GO:0048156; GO:0048471; GO:0048487; GO:0048668; GO:0048843; GO:0050775; GO:0051412; GO:0051646; GO:0051787; GO:0051788; GO:0051879; GO:0051968; GO:0060997; GO:0061523; GO:0061734; GO:0070201; GO:0070301; GO:0070840; GO:0070842; GO:0070845; GO:0070846; GO:0070848; GO:0071218; GO:0071374; GO:0071548; GO:0090042; GO:0090044; GO:0098779; GO:1901300; GO:1901984; GO:1903223; GO:1904056; GO:1904115; GO:2000273 7982 XM_044320601.1 636 444 235 501 500 Q9Z2V5 2.71e-109 Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Histone deacetylase mHDA2) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-) Mus musculus (Mouse) aggresome assembly [GO:0070842]; axonal transport of mitochondrion [GO:0019896]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to misfolded protein [GO:0071218]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to topologically incorrect protein [GO:0035967]; cilium disassembly [GO:0061523]; collateral sprouting [GO:0048668]; dendritic spine morphogenesis [GO:0060997]; epigenetic regulation of gene expression [GO:0040029]; histone deacetylation [GO:0016575]; Hsp90 deacetylation [GO:0070846]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; mitochondrion localization [GO:0051646]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of protein-containing complex disassembly [GO:0043242]; negative regulation of proteolysis [GO:0045861]; negative regulation of transcription by RNA polymerase II [GO:0000122]; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:0061734]; peptidyl-lysine deacetylation [GO:0034983]; polyubiquitinated misfolded protein transport [GO:0070845]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of hydrogen peroxide-mediated programmed cell death [GO:1901300]; positive regulation of mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of tubulin deacetylation [GO:0090044]; protein deacetylation [GO:0006476]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; protein-containing complex disassembly [GO:0032984]; regulation of establishment of protein localization [GO:0070201]; regulation of fat cell differentiation [GO:0045598]; regulation of macroautophagy [GO:0016241]; regulation of mitochondrion organization [GO:0010821]; regulation of protein stability [GO:0031647]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]; response to dexamethasone [GO:0071548]; response to growth factor [GO:0070848]; response to immobilization stress [GO:0035902]; response to misfolded protein [GO:0051788]; tubulin deacetylation [GO:0090042]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] GO:0000118; GO:0000122; GO:0000209; GO:0000978; GO:0001222; GO:0001975; GO:0003779; GO:0004407; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0005829; GO:0005874; GO:0005875; GO:0005901; GO:0006476; GO:0006511; GO:0006515; GO:0006886; GO:0007026; GO:0008013; GO:0008017; GO:0008270; GO:0010634; GO:0010821; GO:0015630; GO:0016234; GO:0016235; GO:0016241; GO:0016575; GO:0019896; GO:0030424; GO:0030425; GO:0031252; GO:0031333; GO:0031593; GO:0031625; GO:0031647; GO:0031648; GO:0032418; GO:0032984; GO:0032991; GO:0033138; GO:0033558; GO:0034983; GO:0035902; GO:0035967; GO:0036064; GO:0040029; GO:0042826; GO:0042903; GO:0043005; GO:0043014; GO:0043025; GO:0043130; GO:0043162; GO:0043204; GO:0043242; GO:0045598; GO:0045861; GO:0048156; GO:0048471; GO:0048487; GO:0048668; GO:0048843; GO:0050775; GO:0051412; GO:0051646; GO:0051787; GO:0051788; GO:0051879; GO:0051968; GO:0060997; GO:0061523; GO:0061734; GO:0070201; GO:0070301; GO:0070840; GO:0070842; GO:0070845; GO:0070846; GO:0070848; GO:0071218; GO:0071374; GO:0071548; GO:0090042; GO:0090044; GO:0098779; GO:1901300; GO:1901984; GO:1903223; GO:1904056; GO:1904115; GO:2000273 7983 XM_044326182.1 25 42 47 49 126 NA NA NA NA NA NA 7984 XM_029335676.2 2013 1085 900 2584 2073 Q8IYT8 2.12e-99 Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2) Homo sapiens (Human) autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; axon extension [GO:0048675]; collateral sprouting [GO:0048668]; late nucleophagy [GO:0044805]; negative regulation of collateral sprouting [GO:0048671]; peptidyl-serine phosphorylation [GO:0018105]; piecemeal microautophagy of the nucleus [GO:0034727]; positive regulation of autophagy [GO:0010508]; protein autophosphorylation [GO:0046777]; response to starvation [GO:0042594]; reticulophagy [GO:0061709]; signal transduction [GO:0007165] GO:0000045; GO:0000422; GO:0004674; GO:0005524; GO:0005737; GO:0006914; GO:0007165; GO:0010508; GO:0018105; GO:0030659; GO:0034045; GO:0034727; GO:0042594; GO:0044805; GO:0046777; GO:0048668; GO:0048671; GO:0048675; GO:0061709; GO:0106310 7985 XM_029335676.2 2013 1085 900 2584 2073 Q8IYT8 2.13e-36 Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2) Homo sapiens (Human) autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; axon extension [GO:0048675]; collateral sprouting [GO:0048668]; late nucleophagy [GO:0044805]; negative regulation of collateral sprouting [GO:0048671]; peptidyl-serine phosphorylation [GO:0018105]; piecemeal microautophagy of the nucleus [GO:0034727]; positive regulation of autophagy [GO:0010508]; protein autophosphorylation [GO:0046777]; response to starvation [GO:0042594]; reticulophagy [GO:0061709]; signal transduction [GO:0007165] GO:0000045; GO:0000422; GO:0004674; GO:0005524; GO:0005737; GO:0006914; GO:0007165; GO:0010508; GO:0018105; GO:0030659; GO:0034045; GO:0034727; GO:0042594; GO:0044805; GO:0046777; GO:0048668; GO:0048671; GO:0048675; GO:0061709; GO:0106310 7986 XM_029327150.2 3217 1738 988 2517 3258 Q96DM1 2.02e-45 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 7987 XM_029327175.2 37 87 56 23 333 O54853 6e-94 Potassium voltage-gated channel subfamily H member 6 (Ether-a-go-go-related gene potassium channel 2) (ERG-2) (Eag-related protein 2) (Ether-a-go-go-related protein 2) (Voltage-gated potassium channel subunit Kv11.2) Rattus norvegicus (Rat) membrane repolarization during action potential [GO:0086011]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307] GO:0005242; GO:0005249; GO:0005267; GO:0005886; GO:0006813; GO:0034765; GO:0042391; GO:0044877; GO:0060307; GO:0071805; GO:0086011; GO:0086091 7988 XM_044318667.1 356 132 0 0 155 O75899 1.05e-71 Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51) (HG20) Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway [GO:0007186]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; neuron-glial cell signaling [GO:0150099]; synaptic transmission, GABAergic [GO:0051932] GO:0004888; GO:0004965; GO:0005737; GO:0005886; GO:0007186; GO:0007193; GO:0007194; GO:0007214; GO:0007268; GO:0038039; GO:0043005; GO:0045211; GO:0046982; GO:0051932; GO:0150099; GO:1902710; GO:1902712 7989 XM_029329771.2 23 0 0 0 0 NA NA NA NA NA NA 7990 XR_006395114.1 52 19 76 0 218 NA NA NA NA NA NA 7991 XM_044322999.1 0 1 12 26 26 NA NA NA NA NA NA 7992 XM_044319921.1 0 6 1 6 4 NA NA NA NA NA NA 7993 XM_044316946.1 3 10 5 1 1 NA NA NA NA NA NA 7994 XM_044317035.1 0 0 21 0 12 P79888 4.55e-95 S-adenosylmethionine decarboxylase proenzyme (AdoMetDC) (SAMDC) (EC 4.1.1.50) [Cleaved into: S-adenosylmethionine decarboxylase alpha chain; S-adenosylmethionine decarboxylase beta chain] Xenopus laevis (African clawed frog) spermidine biosynthetic process [GO:0008295]; spermine biosynthetic process [GO:0006597] GO:0004014; GO:0006597; GO:0008295 7995 XR_003826769.2 35 15 28 51 6 NA NA NA NA NA NA 7996 XM_044324131.1 20 314 205 254 362 Q5R448 1.07e-72 DDB1- and CUL4-associated factor 8 (WD repeat-containing protein 42A) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) protein ubiquitination [GO:0016567] GO:0005634; GO:0005737; GO:0016567; GO:0080008 7997 XM_044321286.1 70 891 467 0 0 Q7RTR2 5.77e-39 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 7998 XM_044321286.1 70 891 467 0 0 Q7RTR2 8.84e-36 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 7999 XM_044321286.1 70 891 467 0 0 Q7RTR2 5.34e-32 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 8000 XM_044321286.1 70 891 467 0 0 Q7RTR2 3.41e-30 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 8001 XM_044321286.1 70 891 467 0 0 Q7RTR2 4.86e-29 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 8002 XM_044327639.1 2 17 4 0 21 NA NA NA NA NA NA 8003 XM_044326750.1 20 37 11 52 3 NA NA NA NA NA NA 8004 XM_029330172.2 799 917 412 606 475 A4UTP7 3.07e-63 Myocyte-specific enhancer factor 2C Sus scrofa (Pig) B cell homeostasis [GO:0001782]; B cell proliferation [GO:0042100]; B cell receptor signaling pathway [GO:0050853]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cardiac ventricle formation [GO:0003211]; cardiocyte differentiation [GO:0035051]; cellular response to calcium ion [GO:0071277]; cellular response to fluid shear stress [GO:0071498]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cellular response to trichostatin A [GO:0035984]; cellular response to xenobiotic stimulus [GO:0071466]; chondrocyte differentiation [GO:0002062]; endochondral ossification [GO:0001958]; epithelial cell proliferation involved in renal tubule morphogenesis [GO:2001013]; germinal center formation [GO:0002467]; glomerulus morphogenesis [GO:0072102]; heart development [GO:0007507]; heart looping [GO:0001947]; humoral immune response [GO:0006959]; learning or memory [GO:0007611]; MAPK cascade [GO:0000165]; melanocyte differentiation [GO:0030318]; muscle cell fate determination [GO:0007521]; negative regulation of gene expression [GO:0010629]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of ossification [GO:0030279]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nephron tubule epithelial cell differentiation [GO:0072160]; neural crest cell differentiation [GO:0014033]; neuron development [GO:0048666]; neuron differentiation [GO:0030182]; osteoblast differentiation [GO:0001649]; outflow tract morphogenesis [GO:0003151]; platelet formation [GO:0030220]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of behavioral fear response [GO:2000987]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cardiac muscle cell differentiation [GO:2000727]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of macrophage apoptotic process [GO:2000111]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of skeletal muscle cell differentiation [GO:2001016]; positive regulation of skeletal muscle tissue development [GO:0048643]; positive regulation of transcription by RNA polymerase II [GO:0045944]; primary heart field specification [GO:0003138]; regulation of germinal center formation [GO:0002634]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of synaptic activity [GO:0060025]; regulation of transcription by RNA polymerase II [GO:0006357]; renal tubule morphogenesis [GO:0061333]; secondary heart field specification [GO:0003139]; sinoatrial valve morphogenesis [GO:0003185]; skeletal muscle tissue development [GO:0007519]; smooth muscle cell differentiation [GO:0051145]; ventricular cardiac muscle cell differentiation [GO:0055012] GO:0000122; GO:0000165; GO:0000976; GO:0000977; GO:0000978; GO:0000981; GO:0001228; GO:0001568; GO:0001649; GO:0001782; GO:0001947; GO:0001958; GO:0001974; GO:0002062; GO:0002467; GO:0002634; GO:0003138; GO:0003139; GO:0003151; GO:0003185; GO:0003211; GO:0003677; GO:0003700; GO:0005634; GO:0005737; GO:0006357; GO:0006959; GO:0007507; GO:0007519; GO:0007521; GO:0007611; GO:0010628; GO:0010629; GO:0010694; GO:0014033; GO:0016528; GO:0016607; GO:0030182; GO:0030220; GO:0030279; GO:0030318; GO:0030501; GO:0030890; GO:0032991; GO:0035051; GO:0035984; GO:0042100; GO:0043524; GO:0045652; GO:0045663; GO:0045666; GO:0045669; GO:0045893; GO:0045944; GO:0046983; GO:0048643; GO:0048666; GO:0050853; GO:0051145; GO:0055012; GO:0060025; GO:0060045; GO:0061333; GO:0071222; GO:0071277; GO:0071374; GO:0071466; GO:0071498; GO:0071560; GO:0072102; GO:0072160; GO:2000111; GO:2000727; GO:2000987; GO:2001013; GO:2001016 8005 XM_044307084.1 0 13 64 116 39 P97363 0 Serine palmitoyltransferase 2 (EC 2.3.1.50) (Long chain base biosynthesis protein 2) (LCB 2) (Long chain base biosynthesis protein 2a) (LCB2a) (Serine-palmitoyl-CoA transferase 2) (SPT 2) Mus musculus (Mouse) adipose tissue development [GO:0060612]; ceramide biosynthetic process [GO:0046513]; lipophagy [GO:0061724]; positive regulation of lipophagy [GO:1904504]; sphinganine biosynthetic process [GO:0046511]; sphingolipid biosynthetic process [GO:0030148]; sphingomyelin biosynthetic process [GO:0006686]; sphingosine biosynthetic process [GO:0046512] GO:0004758; GO:0005739; GO:0005789; GO:0006686; GO:0017059; GO:0030148; GO:0030170; GO:0046511; GO:0046512; GO:0046513; GO:0060612; GO:0061724; GO:1904504 8006 XM_044322044.1 616 424 350 638 479 NA NA NA NA NA NA 8007 XM_044322626.1 186 62 0 1 32 NA NA NA NA NA NA 8008 XR_006394574.1 12 13 0 15 3 NA NA NA NA NA NA 8009 XM_044312607.1 0 0 0 0 46 NA NA NA NA NA NA 8010 XR_003827436.2 4 5 0 10 0 NA NA NA NA NA NA 8011 XM_029358253.2 0 0 68 0 23 NA NA NA NA NA NA 8012 XM_044315198.1 52 6 51 1 16 NA NA NA NA NA NA 8013 XR_006391990.1 45 30 58 0 380 NA NA NA NA NA NA 8014 XM_029355409.2 0 36 13 43 24 NA NA NA NA NA NA 8015 XM_044319470.1 26 4 2 19 0 NA NA NA NA NA NA 8016 XM_044307558.1 20581 53190 9773 22905 4310 NA NA NA NA NA NA 8017 XM_029356538.2 2566 1843 2209 2201 1660 Q9WUP7 5.75e-150 Ubiquitin carboxyl-terminal hydrolase isozyme L5 (UCH-L5) (EC 3.4.19.12) (Ubiquitin C-terminal hydrolase UCH37) (Ubiquitin thioesterase L5) Mus musculus (Mouse) chromatin remodeling [GO:0006338]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; forebrain morphogenesis [GO:0048853]; lateral ventricle development [GO:0021670]; midbrain development [GO:0030901]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of telomere maintenance in response to DNA damage [GO:1904507]; protein deubiquitination [GO:0016579]; regulation of cell cycle [GO:0051726]; regulation of chromosome organization [GO:0033044]; regulation of DNA repair [GO:0006282]; regulation of DNA replication [GO:0006275]; regulation of DNA strand elongation [GO:0060382]; regulation of embryonic development [GO:0045995]; regulation of proteasomal protein catabolic process [GO:0061136]; telomere maintenance [GO:0000723]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000723; GO:0004843; GO:0004866; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0006275; GO:0006281; GO:0006282; GO:0006310; GO:0006338; GO:0006511; GO:0016579; GO:0021670; GO:0030901; GO:0031011; GO:0031597; GO:0032435; GO:0033044; GO:0045739; GO:0045880; GO:0045893; GO:0045995; GO:0048853; GO:0051726; GO:0060382; GO:0061136; GO:0070628; GO:1904507 8018 XM_029333661.2 876 806 608 687 699 NA NA NA NA NA NA 8019 XM_044311526.1 21 1 8 5 54 Q3UPY5 5.97e-157 Beta-galactosidase-1-like protein 2 (EC 3.2.1.-) Mus musculus (Mouse) carbohydrate metabolic process [GO:0005975] GO:0004565; GO:0005576; GO:0005764; GO:0005773; GO:0005975 8020 XM_044324057.1 2455 1801 1475 2711 2457 Q93008 0 Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.4.19.12) (Deubiquitinating enzyme FAF-X) (Fat facets in mammals) (hFAM) (Fat facets protein-related, X-linked) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin-specific-processing protease FAF-X) Homo sapiens (Human) amyloid fibril formation [GO:1990000]; axon extension [GO:0048675]; BMP signaling pathway [GO:0030509]; cell division [GO:0051301]; cell migration [GO:0016477]; chromosome segregation [GO:0007059]; female gamete generation [GO:0007292]; monoubiquitinated protein deubiquitination [GO:0035520]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron migration [GO:0001764]; positive regulation of DNA demethylation [GO:1901537]; positive regulation of protein binding [GO:0032092]; positive regulation of TORC2 signaling [GO:1904515]; protein deubiquitination [GO:0016579]; protein deubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0071947]; protein import into peroxisome matrix, receptor recycling [GO:0016562]; protein K63-linked deubiquitination [GO:0070536]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0000122; GO:0001764; GO:0004197; GO:0004843; GO:0005634; GO:0005737; GO:0005829; GO:0005856; GO:0005929; GO:0007059; GO:0007179; GO:0007292; GO:0008104; GO:0008234; GO:0016020; GO:0016477; GO:0016562; GO:0016567; GO:0016579; GO:0030426; GO:0030509; GO:0032092; GO:0032435; GO:0035520; GO:0042752; GO:0048511; GO:0048675; GO:0050821; GO:0051301; GO:0061578; GO:0070410; GO:0070536; GO:0071947; GO:0101005; GO:1901537; GO:1904515; GO:1990000; GO:1990380 8021 XR_006392176.1 27 18 3 3 11 NA NA NA NA NA NA 8022 XR_003823016.1 29 34 56 30 35 NA NA NA NA NA NA 8023 XM_044316870.1 1154 1510 943 1260 829 Q8R367 3.88e-33 Ras-related and estrogen-regulated growth inhibitor (EC 3.6.5.2) Mus musculus (Mouse) negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; Ras protein signal transduction [GO:0007265]; response to hormone [GO:0009725] GO:0001650; GO:0003924; GO:0003925; GO:0005525; GO:0005634; GO:0005654; GO:0005829; GO:0005886; GO:0007265; GO:0008285; GO:0009725; GO:0019003; GO:0030308 8024 XM_029344775.2 0 0 2 0 6 NA NA NA NA NA NA 8025 XM_029326998.2 46 44 30 34 61 Q9NZI7 1.63e-64 Upstream-binding protein 1 (Transcription factor LBP-1) Homo sapiens (Human) angiogenesis [GO:0001525]; negative regulation of viral transcription [GO:0032897]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000785; GO:0000978; GO:0000981; GO:0001228; GO:0001525; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0032897; GO:0045944; GO:1990837 8026 XM_044326743.1 3 3 15 19 5 NA NA NA NA NA NA 8027 XR_006398138.1 0 0 0 0 10 NA NA NA NA NA NA 8028 XM_044315811.1 35 10 0 917 1146 NA NA NA NA NA NA 8029 XM_029336202.2 1803 1805 968 1793 1996 Q2HJF7 0 Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta) (CaMK-II subunit delta) (EC 2.7.11.17) Bos taurus (Bovine) positive regulation of cardiac muscle hypertrophy [GO:0010613]; protein phosphorylation [GO:0006468]; regulation of cellular localization [GO:0060341] GO:0004683; GO:0005516; GO:0005524; GO:0005737; GO:0006468; GO:0010613; GO:0033017; GO:0042383; GO:0043005; GO:0060341; GO:0106310 8030 XM_029333023.2 132 116 102 81 152 P30937 7.56e-21 Somatostatin receptor type 4 (SS-4-R) (SS4-R) (SS4R) Rattus norvegicus (Rat) cell migration [GO:0016477]; cellular response to glucocorticoid stimulus [GO:0071385]; forebrain development [GO:0030900]; negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0106072]; neuropeptide signaling pathway [GO:0007218]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0004930; GO:0004994; GO:0005737; GO:0005886; GO:0007218; GO:0016477; GO:0030900; GO:0042277; GO:0042923; GO:0043005; GO:0070374; GO:0071385; GO:0090238; GO:0106072 8031 XM_044308228.1 25 44 162 81 660 Q9BU40 1.86e-26 Chordin-like protein 1 (Neuralin-1) (Neurogenesin-1) (Ventroptin) Homo sapiens (Human) AMPA glutamate receptor clustering [GO:0097113]; BMP signaling pathway [GO:0030509]; cell differentiation [GO:0030154]; embryonic axis specification [GO:0000578]; excitatory chemical synaptic transmission [GO:0098976]; eye development [GO:0001654]; negative regulation of BMP signaling pathway [GO:0030514]; ossification [GO:0001503]; regulation of synaptic plasticity [GO:0048167]; synapse maturation [GO:0060074] GO:0000578; GO:0001503; GO:0001654; GO:0005576; GO:0005788; GO:0005886; GO:0030154; GO:0030509; GO:0030514; GO:0036122; GO:0045202; GO:0048167; GO:0050431; GO:0060074; GO:0097113; GO:0098976 8032 XM_044318441.1 4 0 0 8 0 NA NA NA NA NA NA 8033 XM_029338837.2 0 0 0 40 0 O88871 2.92e-140 Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51) Rattus norvegicus (Rat) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; gamma-aminobutyric acid signaling pathway [GO:0007214]; neuron-glial cell signaling [GO:0150099]; synaptic transmission, GABAergic [GO:0051932] GO:0004888; GO:0004965; GO:0005737; GO:0005886; GO:0007193; GO:0007214; GO:0016020; GO:0030425; GO:0038039; GO:0042734; GO:0043005; GO:0043204; GO:0045211; GO:0046982; GO:0051932; GO:0098978; GO:0098982; GO:0150099; GO:1902710; GO:1902712 8034 XM_044309920.1 826 59 1213 210 6959 NA NA NA NA NA NA 8035 XM_029328177.2 910 611 618 757 802 Q9NZ56 1.57e-95 Formin-2 Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hypoxia [GO:0071456]; establishment of meiotic spindle localization [GO:0051295]; formin-nucleated actin cable assembly [GO:0070649]; homologous chromosome movement towards spindle pole in meiosis I anaphase [GO:0051758]; intracellular signal transduction [GO:0035556]; intracellular transport [GO:0046907]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein catabolic process [GO:0042177]; oogenesis [GO:0048477]; polar body extrusion after meiotic divisions [GO:0040038]; positive regulation of double-strand break repair [GO:2000781]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] GO:0003779; GO:0005634; GO:0005730; GO:0005737; GO:0005783; GO:0005789; GO:0005819; GO:0005829; GO:0005886; GO:0005902; GO:0005938; GO:0006974; GO:0015031; GO:0016192; GO:0016477; GO:0030659; GO:0031532; GO:0035556; GO:0040038; GO:0042177; GO:0043066; GO:0046907; GO:0048471; GO:0048477; GO:0051295; GO:0051758; GO:0070649; GO:0071456; GO:2000781 8036 XM_029338623.2 15 24 18 44 11 Q5T7P8 3.96e-42 Synaptotagmin-6 (Synaptotagmin VI) (SytVI) Homo sapiens (Human) acrosomal vesicle exocytosis [GO:0060478]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; vesicle-mediated transport [GO:0016192] GO:0000149; GO:0001786; GO:0005509; GO:0005829; GO:0005886; GO:0014059; GO:0016020; GO:0016192; GO:0017156; GO:0017158; GO:0019898; GO:0019905; GO:0030276; GO:0030672; GO:0042803; GO:0060478; GO:0070382; GO:0071277; GO:0097038 8037 XR_003823549.2 0 2 0 31 64 NA NA NA NA NA NA 8038 XM_044321555.1 43 0 0 0 0 NA NA NA NA NA NA 8039 XM_029356200.2 347 139 135 190 274 Q54PR9 1.92e-50 Counting factor 60 Dictyostelium discoideum (Social amoeba) dephosphorylation [GO:0016311]; negative regulation of aggregate size involved in sorocarp development [GO:0031158] GO:0005576; GO:0016311; GO:0016791; GO:0031158 8040 XR_006396743.1 168 224 177 258 304 NA NA NA NA NA NA 8041 XM_044319977.1 351 69 58 257 136 NA NA NA NA NA NA 8042 XM_044321331.1 0 27 0 0 0 P46023 4.05e-90 G-protein coupled receptor GRL101 Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004930; GO:0005886 8043 XM_029331228.2 466 350 233 394 232 NA NA NA NA NA NA 8044 XM_044324311.1 181 113 98 71 177 Q568Q0 8.61e-35 8-oxo-dGDP phosphatase NUDT18 (EC 3.6.1.58) (2-hydroxy-dADP phosphatase) (7,8-dihydro-8-oxoguanine phosphatase) (Nucleoside diphosphate-linked moiety X motif 18) (Nudix motif 18) Danio rerio (Zebrafish) (Brachydanio rerio) dADP catabolic process [GO:0046057]; dGDP catabolic process [GO:0046067]; GDP catabolic process [GO:0046712] GO:0000287; GO:0044715; GO:0044716; GO:0044717; GO:0046057; GO:0046067; GO:0046712 8045 XM_029344609.2 917 1034 531 822 846 Q5R991 5.33e-61 Late secretory pathway protein AVL9 homolog Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cell migration [GO:0016477] GO:0016020; GO:0016477; GO:0055037 8046 XM_029344609.2 917 1034 531 822 846 Q5R991 1.28e-41 Late secretory pathway protein AVL9 homolog Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cell migration [GO:0016477] GO:0016020; GO:0016477; GO:0055037 8047 XR_003825460.2 23 92 72 72 69 NA NA NA NA NA NA 8048 XM_029348438.2 1098 1220 368 955 1085 NA NA NA NA NA NA 8049 XM_029356364.2 107 5 58 36 141 P55112 3.32e-37 Zinc metalloproteinase nas-4 (EC 3.4.24.-) (Nematode astacin 4) Caenorhabditis elegans proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0006508; GO:0008270 8050 XM_044319569.1 232 0 74 66 0 O94762 0 ATP-dependent DNA helicase Q5 (EC 3.6.4.12) (DNA helicase, RecQ-like type 5) (RecQ5) (RecQ protein-like 5) Homo sapiens (Human) cell division [GO:0051301]; cellular response to camptothecin [GO:0072757]; cellular response to ketone [GO:1901655]; cellular response to xenobiotic stimulus [GO:0071466]; chromosome separation [GO:0051304]; DNA duplex unwinding [GO:0032508]; DNA metabolic process [GO:0006259]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724]; mitotic cell cycle [GO:0000278]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; negative regulation of transcription elongation by RNA polymerase II [GO:0034244]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414] GO:0000278; GO:0000724; GO:0000993; GO:0003676; GO:0003678; GO:0005524; GO:0005634; GO:0005654; GO:0005694; GO:0005737; GO:0005829; GO:0006259; GO:0006260; GO:0006268; GO:0006281; GO:0006310; GO:0009378; GO:0016591; GO:0016887; GO:0032508; GO:0034244; GO:0042802; GO:0043138; GO:0051301; GO:0051304; GO:0071466; GO:0072757; GO:1901655; GO:1990414; GO:2000042 8051 XM_029333982.2 239 105 145 172 99 NA NA NA NA NA NA 8052 XM_029346843.2 212 141 112 134 207 NA NA NA NA NA NA 8053 XR_006397196.1 153 136 69 148 227 NA NA NA NA NA NA 8054 XM_044320986.1 52 89 44 72 62 Q9VBW3 1.98e-60 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 8055 XM_044319058.1 133 188 2 88 90 NA NA NA NA NA NA 8056 XM_029353525.2 204 174 100 192 317 Q9BU70 7.74e-57 tRNA (adenine(37)-N6)-methyltransferase (EC 2.1.1.-) (tRNA methyltransferase O) Homo sapiens (Human) tRNA methylation [GO:0030488] GO:0030488; GO:0089715 8057 XM_029337686.2 1008 1015 483 840 455 NA NA NA NA NA NA 8058 XM_044324285.1 2834 1591 643 3279 3711 Q3SYW2 1.72e-62 Complement C2 (EC 3.4.21.43) (C3/C5 convertase) [Cleaved into: Complement C2b fragment; Complement C2a fragment] Bos taurus (Bovine) complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; proteolysis [GO:0006508]; response to bacterium [GO:0009617] GO:0004252; GO:0005601; GO:0006508; GO:0006956; GO:0006958; GO:0009617; GO:0045087; GO:0046872 8059 XM_029339828.2 198 193 78 313 287 G8HTB6 2.91e-38 ZP domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 8060 XR_006393739.1 0 11 0 0 17 NA NA NA NA NA NA 8061 XM_044307744.1 2 0 0 15 0 P0DP43 5.4e-28 Cation channel sperm-associated auxiliary subunit epsilon (CatSper-epsilon) (CatSperepsilon) (C1orf101-like protein) Mus musculus (Mouse) flagellated sperm motility [GO:0030317]; sperm capacitation [GO:0048240] GO:0030317; GO:0036128; GO:0048240; GO:0097228 8062 XR_006391394.1 17 1 12 1 47 NA NA NA NA NA NA 8063 XM_044315768.1 37 67 75 85 99 E1BGQ2 7.91e-115 rRNA N6-adenosine-methyltransferase ZCCHC4 (EC 2.1.1.-) (Zinc finger CCHC domain-containing protein 4) Bos taurus (Bovine) positive regulation of translation [GO:0045727]; rRNA methylation [GO:0031167] GO:0003676; GO:0005730; GO:0005737; GO:0008270; GO:0008988; GO:0031167; GO:0045727; GO:1904047 8064 XM_044307288.1 0 12 0 0 0 D2IYS2 8.95e-65 Tyrosine-protein kinase receptor torso (EC 2.7.10.1) Bombyx mori (Silk moth) NA GO:0004714; GO:0005524; GO:0005886; GO:0046872 8065 XM_044322457.1 15 5 9 0 87 Q96AY4 2.24e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8066 XM_044322457.1 15 5 9 0 87 Q96AY4 2.25e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8067 XM_044322457.1 15 5 9 0 87 Q96AY4 1.56e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8068 XM_044322457.1 15 5 9 0 87 Q96AY4 2.3e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8069 XM_044322457.1 15 5 9 0 87 Q96AY4 7.16e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8070 XM_044322457.1 15 5 9 0 87 Q96AY4 1.46e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8071 XM_044322457.1 15 5 9 0 87 Q96AY4 1.98e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8072 XM_044322457.1 15 5 9 0 87 Q96AY4 2.64e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8073 XM_044322457.1 15 5 9 0 87 Q96AY4 4.8e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8074 XM_044322457.1 15 5 9 0 87 Q96AY4 2.31e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8075 XM_044322457.1 15 5 9 0 87 Q96AY4 9.34e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8076 XM_029350049.2 196 98 229 228 420 NA NA NA NA NA NA 8077 XM_029346322.2 582 392 480 617 797 NA NA NA NA NA NA 8078 XM_029356146.2 18 32 17 18 23 NA NA NA NA NA NA 8079 XM_029347912.2 19 0 4 13 45 NA NA NA NA NA NA 8080 XM_029324959.2 150 65 9 27 45 NA NA NA NA NA NA 8081 XR_006395537.1 0 0 2 0 209 P53992 0 Protein transport protein Sec24C (SEC24-related protein C) Homo sapiens (Human) COPII-coated vesicle cargo loading [GO:0090110]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; in utero embryonic development [GO:0001701]; intracellular protein transport [GO:0006886] GO:0000149; GO:0001701; GO:0005789; GO:0005829; GO:0006886; GO:0006888; GO:0008270; GO:0012507; GO:0030127; GO:0070971; GO:0090110 8082 XM_029352063.2 0 0 2 0 29 P35187 3.48e-48 ATP-dependent helicase SGS1 (EC 3.6.4.12) (Helicase TPS1) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) chromosome organization [GO:0051276]; DNA double-strand break processing [GO:0000729]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA topological change [GO:0006265]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724]; gene conversion at mating-type locus [GO:0007534]; meiotic chromosome segregation [GO:0045132]; meiotic DNA double-strand break processing [GO:0000706]; mitotic G2/M transition checkpoint [GO:0044818]; mitotic intra-S DNA damage checkpoint signaling [GO:0031573]; mitotic sister chromatid segregation [GO:0000070]; negative regulation of meiotic joint molecule formation [GO:0010947]; regulation of reciprocal meiotic recombination [GO:0010520]; telomere maintenance [GO:0000723]; telomere maintenance via recombination [GO:0000722]; telomeric 3' overhang formation [GO:0031860] GO:0000070; GO:0000706; GO:0000722; GO:0000723; GO:0000724; GO:0000729; GO:0003676; GO:0005524; GO:0005634; GO:0005694; GO:0005730; GO:0005737; GO:0006265; GO:0006268; GO:0006281; GO:0006310; GO:0007534; GO:0009378; GO:0010520; GO:0010947; GO:0016887; GO:0031422; GO:0031573; GO:0031860; GO:0032508; GO:0043138; GO:0044818; GO:0045132; GO:0051276 8083 XM_044307296.1 25 0 0 0 0 Q9D5U8 7.82e-43 Cyclic nucleotide-binding domain-containing protein 2 (Cyclic nucleotide receptor involved in sperm function) Mus musculus (Mouse) spermatogenesis [GO:0007283] GO:0005829; GO:0007283; GO:0030552 8084 XM_044328232.1 384 242 177 275 165 Q6P1R4 5.69e-124 tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like (EC 1.3.1.88) (tRNA-dihydrouridine synthase 1-like) Homo sapiens (Human) tRNA dihydrouridine synthesis [GO:0002943] GO:0002943; GO:0017150; GO:0050660 8085 XM_029356212.2 0 37 31 3 30 Q0VCJ7 3.01e-30 Ras-related and estrogen-regulated growth inhibitor (EC 3.6.5.2) Bos taurus (Bovine) negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; Ras protein signal transduction [GO:0007265]; response to hormone [GO:0009725] GO:0001650; GO:0003924; GO:0003925; GO:0005525; GO:0005654; GO:0005829; GO:0005886; GO:0007265; GO:0008285; GO:0009725; GO:0019003; GO:0030308 8086 XM_044326172.1 18 0 16 0 15 Q09575 1.99e-31 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 8087 XM_044320416.1 1003 0 348 181 0 NA NA NA NA NA NA 8088 XM_044323084.1 53 288 156 21 100 NA NA NA NA NA NA 8089 XM_029330996.2 0 6 0 0 0 NA NA NA NA NA NA 8090 XM_044307811.1 2 0 6 8 4 NA NA NA NA NA NA 8091 XM_029346334.2 468 1199 251 523 307 E7FAM5 2.89e-136 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 8092 XM_044322674.1 0 4 7 17 10 Q5XI14 2.38e-93 Minichromosome maintenance domain-containing protein 2 (MCM domain-containing protein 2) Rattus norvegicus (Rat) DNA duplex unwinding [GO:0032508]; double-strand break repair involved in meiotic recombination [GO:1990918]; double-strand break repair via break-induced replication [GO:0000727]; late meiotic recombination nodule assembly [GO:0042140]; meiotic recombination nodule assembly [GO:0007146]; oogenesis [GO:0048477]; spermatogenesis [GO:0007283]; synaptonemal complex assembly [GO:0007130] GO:0000727; GO:0003677; GO:0005524; GO:0007130; GO:0007146; GO:0007283; GO:0032508; GO:0042140; GO:0048477; GO:1990918 8093 XM_029330934.2 7 0 86 62 52 Q8C0J2 8.13e-124 Autophagy-related protein 16-1 (APG16-like 1) Mus musculus (Mouse) autophagosome assembly [GO:0000045]; C-terminal protein lipidation [GO:0006501]; corpus callosum development [GO:0022038]; defense response to virus [GO:0051607]; hippocampus development [GO:0021766]; lysosomal microautophagy [GO:0016237]; macroautophagy [GO:0016236]; negative stranded viral RNA replication [GO:0039689]; positive regulation of autophagy [GO:0010508]; protein lipidation [GO:0006497]; protein lipidation involved in autophagosome assembly [GO:0061739]; protein localization to phagophore assembly site [GO:0034497]; protein transport [GO:0015031]; xenophagy [GO:0098792] GO:0000045; GO:0000421; GO:0005737; GO:0005776; GO:0005829; GO:0005930; GO:0006497; GO:0006501; GO:0010508; GO:0015031; GO:0016236; GO:0016237; GO:0021766; GO:0022038; GO:0034045; GO:0034274; GO:0034497; GO:0036020; GO:0039689; GO:0042802; GO:0051020; GO:0051607; GO:0061739; GO:0097225; GO:0098792; GO:0120095 8094 XM_044322068.1 139 63 362 114 492 Q17RP2 7.36e-86 Tigger transposable element-derived protein 6 Homo sapiens (Human) NA GO:0003677; GO:0005634 8095 XM_029344665.2 26 32 22 0 9 Q5R634 5.61e-38 Divergent protein kinase domain 1A (Protein FAM69A) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0005789 8096 XM_029340715.2 5 4 11 10 9 Q3UZD5 3.38e-90 Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.361) (PR domain zinc finger protein 6) (PR domain-containing protein 6) (PR domain-containing protein in smooth muscle) Mus musculus (Mouse) chromatin organization [GO:0006325]; histone methylation [GO:0016571]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of smooth muscle cell differentiation [GO:0051151]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of gene expression [GO:0010468] GO:0000122; GO:0005634; GO:0006325; GO:0010468; GO:0016571; GO:0022008; GO:0042802; GO:0045892; GO:0046872; GO:0051151; GO:0140944 8097 XM_029351391.2 3 5 12 1 11 NA NA NA NA NA NA 8098 XM_029352599.2 203 128 76 104 270 NA NA NA NA NA NA 8099 XM_044321523.1 0 1 16 0 3 NA NA NA NA NA NA 8100 XM_029324400.2 239 163 49 132 218 NA NA NA NA NA NA 8101 XM_044323934.1 16 4 31 11 20 NA NA NA NA NA NA 8102 XR_006395032.1 1 5 5 0 6 NA NA NA NA NA NA 8103 XM_029353084.2 2 0 3 0 30 NA NA NA NA NA NA 8104 XM_029332494.2 56 8 48 16 8 NA NA NA NA NA NA 8105 XM_044323879.1 12 0 3 0 35 NA NA NA NA NA NA 8106 XM_044317001.1 0 1 0 0 18 NA NA NA NA NA NA 8107 XM_044320920.1 0 0 21 3 50 Q9VBW3 1.05e-44 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 8108 XM_029346171.2 2566 3159 1826 2217 1655 Q9CZL5 5.21e-30 Pterin-4-alpha-carbinolamine dehydratase 2 (PHS 2) (EC 4.2.1.96) (4-alpha-hydroxy-tetrahydropterin dehydratase 2) (DcoH-like protein DCoHm) (Dimerization cofactor of hepatocyte nuclear factor 1 from muscle) (HNF-1-alpha dimerization cofactor) Mus musculus (Mouse) positive regulation of DNA-templated transcription [GO:0045893]; tetrahydrobiopterin biosynthetic process [GO:0006729] GO:0004505; GO:0005634; GO:0005739; GO:0006729; GO:0008124; GO:0042802; GO:0045893 8109 XM_044311867.1 0 0 11 3 10 NA NA NA NA NA NA 8110 XM_044325726.1 360 281 412 246 253 NA NA NA NA NA NA 8111 XM_029331132.2 11 28 0 64 16 O64411 7.98e-76 Polyamine oxidase 1 (EC 1.5.3.14) (EC 1.5.3.15) Zea mays (Maize) polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208] GO:0006598; GO:0009505; GO:0016491; GO:0046208; GO:0046592; GO:0048046; GO:0050660; GO:0052893; GO:0052896; GO:0052897; GO:0052900 8112 XM_029333855.2 878 1046 541 1070 859 Q8IWE4 8.56e-75 DCN1-like protein 3 (DCNL3) (DCUN1 domain-containing protein 3) (Defective in cullin neddylation protein 1-like protein 3) (Squamous cell carcinoma-related oncogene 3) Homo sapiens (Human) negative regulation of cell growth [GO:0030308]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of protein neddylation [GO:2000435]; positive regulation of apoptotic process [GO:0043065]; positive regulation of protein neddylation [GO:2000436]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein neddylation [GO:0045116]; regulation of cell cycle process [GO:0010564]; regulation of protein neddylation [GO:2000434]; response to gamma radiation [GO:0010332]; response to UV-C [GO:0010225] GO:0000151; GO:0005634; GO:0005737; GO:0005886; GO:0010225; GO:0010332; GO:0010564; GO:0030308; GO:0031624; GO:0032182; GO:0043065; GO:0045116; GO:0048471; GO:0051443; GO:0097602; GO:2000134; GO:2000434; GO:2000435; GO:2000436 8113 XR_006395806.1 492 308 572 598 507 P95544 2.22e-147 NAD(P)-specific glutamate dehydrogenase (NAD(P)-GDH) (EC 1.4.1.3) (NAD(P)H-dependent glutamate dehydrogenase) Prevotella ruminicola (Bacteroides ruminicola) glutamate biosynthetic process [GO:0006537] GO:0004352; GO:0004353; GO:0004354; GO:0005737; GO:0006537 8114 XR_006395806.1 492 308 572 598 507 P95544 1.62e-27 NAD(P)-specific glutamate dehydrogenase (NAD(P)-GDH) (EC 1.4.1.3) (NAD(P)H-dependent glutamate dehydrogenase) Prevotella ruminicola (Bacteroides ruminicola) glutamate biosynthetic process [GO:0006537] GO:0004352; GO:0004353; GO:0004354; GO:0005737; GO:0006537 8115 XR_006395147.1 0 6 6 0 0 NA NA NA NA NA NA 8116 XM_044319181.1 7867 3006 11500 13413 8724 B3EWZ6 0 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8117 XM_044319181.1 7867 3006 11500 13413 8724 B3EWZ6 0 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8118 XM_044319181.1 7867 3006 11500 13413 8724 B3EWZ6 0 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8119 XM_044319181.1 7867 3006 11500 13413 8724 B3EWZ6 0 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8120 XM_044319181.1 7867 3006 11500 13413 8724 B3EWZ6 0 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8121 XM_044319181.1 7867 3006 11500 13413 8724 B3EWZ6 0 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8122 XM_044319181.1 7867 3006 11500 13413 8724 B3EWZ6 0 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8123 XM_044319181.1 7867 3006 11500 13413 8724 B3EWZ6 1.75e-138 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8124 XM_044319181.1 7867 3006 11500 13413 8724 B3EWZ6 9.74e-105 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8125 XM_044319181.1 7867 3006 11500 13413 8724 B3EWZ6 6.97e-102 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8126 XM_044319181.1 7867 3006 11500 13413 8724 B3EWZ6 3.13e-97 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8127 XM_044319181.1 7867 3006 11500 13413 8724 B3EWZ6 1.1e-95 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8128 XM_044319181.1 7867 3006 11500 13413 8724 B3EWZ6 1.13e-91 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8129 XM_044319181.1 7867 3006 11500 13413 8724 B3EWZ6 4.53e-90 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8130 XM_044319181.1 7867 3006 11500 13413 8724 B3EWZ6 2.02e-86 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8131 XM_044319181.1 7867 3006 11500 13413 8724 B3EWZ6 1.05e-60 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8132 XM_044319181.1 7867 3006 11500 13413 8724 B3EWZ6 6.82e-59 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8133 XM_044319181.1 7867 3006 11500 13413 8724 B3EWZ6 1.75e-58 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8134 XM_044319181.1 7867 3006 11500 13413 8724 B3EWZ6 1.67e-54 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8135 XM_044319181.1 7867 3006 11500 13413 8724 B3EWZ6 4.46e-50 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8136 XM_044319181.1 7867 3006 11500 13413 8724 B3EWZ6 2.24e-42 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8137 XM_044319181.1 7867 3006 11500 13413 8724 B3EWZ6 8.78e-34 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8138 XM_044319181.1 7867 3006 11500 13413 8724 B3EWZ6 3.56e-30 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8139 XM_044319181.1 7867 3006 11500 13413 8724 B3EWZ6 2.98e-27 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8140 XM_044319181.1 7867 3006 11500 13413 8724 B3EWZ6 4.24e-25 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8141 XM_044319181.1 7867 3006 11500 13413 8724 B3EWZ6 3.9e-23 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8142 XM_044319181.1 7867 3006 11500 13413 8724 B3EWZ6 1.51e-22 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8143 XM_044319181.1 7867 3006 11500 13413 8724 B3EWZ6 3.67e-22 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8144 XM_044319181.1 7867 3006 11500 13413 8724 B3EWZ6 8.6e-22 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8145 XM_044321751.1 62 5 17 33 62 Q5ZLG1 5.8e-73 Ras-related protein Rab-18 Gallus gallus (Chicken) brain development [GO:0007420]; eye development [GO:0001654]; intracellular protein transport [GO:0006886]; lipid droplet organization [GO:0034389] GO:0001654; GO:0003924; GO:0005525; GO:0005789; GO:0005794; GO:0005811; GO:0006886; GO:0007420; GO:0012505; GO:0016324; GO:0019003; GO:0034389 8146 XM_044312748.1 0 0 69 63 57 Q17RS7 2.18e-66 Flap endonuclease GEN homolog 1 (EC 3.1.-.-) Homo sapiens (Human) double-strand break repair via homologous recombination [GO:0000724]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; regulation of centrosome duplication [GO:0010824]; replication fork processing [GO:0031297]; resolution of mitotic recombination intermediates [GO:0071140]; resolution of recombination intermediates [GO:0071139] GO:0000287; GO:0000400; GO:0000724; GO:0005654; GO:0005813; GO:0008821; GO:0010824; GO:0017108; GO:0031297; GO:0042803; GO:0071139; GO:0071140; GO:0090267 8147 XR_006396188.1 15 11 48 29 140 NA NA NA NA NA NA 8148 XM_029332333.2 22 0 25 48 15 NA NA NA NA NA NA 8149 XM_044319037.1 86 68 44 88 113 Q08BM0 6.98e-54 tRNA methyltransferase 10 homolog B (EC 2.1.1.221) (RNA (guanine-9-)-methyltransferase domain-containing protein 3) (tRNA (guanine(9)-N(1))-methyltransferase TRMT10B) Danio rerio (Zebrafish) (Brachydanio rerio) tRNA N1-guanine methylation [GO:0002939] GO:0000049; GO:0002939; GO:0005634; GO:0005654; GO:0009019; GO:0052905 8150 XM_029352107.2 1982 1762 850 3112 2879 Q947D2 1.33e-60 PH, RCC1 and FYVE domains-containing protein 1 (Protein Praf4) Arabidopsis thaliana (Mouse-ear cress) NA GO:0005085; GO:0035091; GO:0046872; GO:0070300 8151 XM_044319645.1 7 0 0 4 34 NA NA NA NA NA NA 8152 XM_044311062.1 23 41 56 0 31 NA NA NA NA NA NA 8153 XM_044316322.1 14 1 2 20 57 NA NA NA NA NA NA 8154 XM_044318806.1 0 0 39 0 206 B3EWY9 0 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 8155 XM_044318806.1 0 0 39 0 206 B3EWY9 0 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 8156 XM_044318806.1 0 0 39 0 206 B3EWY9 2.18e-34 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 8157 XM_044318806.1 0 0 39 0 206 B3EWY9 5.02e-33 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 8158 XM_044327383.1 2 11 6 0 0 NA NA NA NA NA NA 8159 XM_044312217.1 36 0 15 0 16 NA NA NA NA NA NA 8160 XM_029342017.2 54 30 29 40 39 NA NA NA NA NA NA 8161 XM_044328015.1 1946 2274 1209 1277 1013 Q6P963 7.22e-111 Hydroxyacylglutathione hydrolase, mitochondrial (EC 3.1.2.6) (Glyoxalase II) (Glx II) Danio rerio (Zebrafish) (Brachydanio rerio) glutathione metabolic process [GO:0006749]; methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243] GO:0004416; GO:0005739; GO:0005759; GO:0006749; GO:0019243; GO:0046872 8162 XM_029350729.2 114 44 68 122 141 NA NA NA NA NA NA 8163 XM_044306834.1 0 29 26 10 0 Q8T882 5.44e-33 Tauropine dehydrogenase (TaDH) (EC 1.5.1.23) (NAD: tauropine oxidoreductase) Arabella iricolor (Opal worm) NA GO:0050325 8164 XM_029331293.2 494 276 263 543 530 Q9UJA9 4.87e-79 Ectonucleotide pyrophosphatase/phosphodiesterase family member 5 (E-NPP 5) (NPP-5) (EC 3.1.-.-) Homo sapiens (Human) cell communication [GO:0007154] GO:0000210; GO:0005576; GO:0005886; GO:0007154; GO:0008270 8165 XR_006393160.1 536 369 511 655 651 NA NA NA NA NA NA 8166 XM_029336947.2 48 24 38 0 0 NA NA NA NA NA NA 8167 XM_029331772.2 4049 1200 332 1049 5906 NA NA NA NA NA NA 8168 XM_029357388.2 172 126 91 103 129 Q2TBW5 5.81e-38 Zinc finger HIT domain-containing protein 2 Bos taurus (Bovine) NA GO:0046872 8169 XM_044321894.1 0 27 0 0 159 NA NA NA NA NA NA 8170 XM_044320277.1 244 539 457 654 432 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 8171 XM_044320277.1 244 539 457 654 432 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 8172 XM_044320277.1 244 539 457 654 432 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 8173 XM_044320277.1 244 539 457 654 432 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 8174 XM_044320277.1 244 539 457 654 432 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 8175 XM_044320277.1 244 539 457 654 432 P07207 1.35e-91 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 8176 XM_044320277.1 244 539 457 654 432 P07207 6.34e-87 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 8177 XM_044320277.1 244 539 457 654 432 P07207 1.16e-78 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 8178 XM_044320277.1 244 539 457 654 432 P07207 3.94e-71 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 8179 XM_044320277.1 244 539 457 654 432 P07207 4.82e-70 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 8180 XM_044320277.1 244 539 457 654 432 P07207 7.31e-63 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 8181 XM_044320277.1 244 539 457 654 432 P07207 1.48e-62 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 8182 XM_044320277.1 244 539 457 654 432 P07207 7.3e-62 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 8183 XM_044320277.1 244 539 457 654 432 P07207 1e-53 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 8184 XM_044320277.1 244 539 457 654 432 P07207 2.78e-50 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 8185 XM_044320277.1 244 539 457 654 432 P07207 1.56e-49 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 8186 XM_044320277.1 244 539 457 654 432 P07207 3.71e-49 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 8187 XM_044320277.1 244 539 457 654 432 P07207 2.77e-45 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 8188 XM_044320277.1 244 539 457 654 432 P07207 5.66e-45 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 8189 XM_044320277.1 244 539 457 654 432 P07207 5.4e-44 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 8190 XM_044320277.1 244 539 457 654 432 P07207 3.39e-43 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 8191 XM_044320277.1 244 539 457 654 432 P07207 2.57e-39 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 8192 XM_044320277.1 244 539 457 654 432 P07207 3.06e-33 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 8193 XM_044320277.1 244 539 457 654 432 P07207 2.46e-30 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 8194 XM_044320277.1 244 539 457 654 432 P07207 7.39e-30 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 8195 XM_044320277.1 244 539 457 654 432 P07207 2.13e-25 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 8196 XM_044320277.1 244 539 457 654 432 P07207 1.7e-22 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 8197 XM_044316360.1 10 2 6 6 14 NA NA NA NA NA NA 8198 XM_044322273.1 39 9 36 39 19 C6KFA3 2.79e-22 Adhesion G-protein coupled receptor G6 (G-protein coupled receptor 126) [Cleaved into: ADGRG6 N-terminal fragment (ADGRG6-NTF); ADGRG6 C-terminal fragment (ADGRG6-CTF)] Danio rerio (Zebrafish) (Brachydanio rerio) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cAMP-mediated signaling [GO:0019933]; cell surface receptor signaling pathway [GO:0007166]; ear development [GO:0043583]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; heart trabecula formation [GO:0060347]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; myelination of posterior lateral line nerve axons [GO:0048932]; ossification [GO:0001503]; peripheral nervous system myelin formation [GO:0032290]; regulation of sprouting angiogenesis [GO:1903670]; Schwann cell differentiation [GO:0014037]; semicircular canal fusion [GO:0060879] GO:0001503; GO:0004930; GO:0005518; GO:0005886; GO:0007005; GO:0007166; GO:0007186; GO:0007189; GO:0007507; GO:0014037; GO:0019933; GO:0022011; GO:0032290; GO:0042552; GO:0043236; GO:0043583; GO:0048932; GO:0050840; GO:0060347; GO:0060879; GO:1903670 8199 XM_029341523.2 131 123 24 0 0 C3ZQF9 1.47e-25 QRFP-like peptide receptor Branchiostoma floridae (Florida lancelet) (Amphioxus) cellular response to peptide [GO:1901653]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:1901653 8200 XM_044315845.1 7 0 0 0 99 P04813 9.94e-39 Chymotrypsinogen 2 (EC 3.4.21.1) [Cleaved into: Chymotrypsin 2 chain A; Chymotrypsin 2 chain B; Chymotrypsin 2 chain C] Canis lupus familiaris (Dog) (Canis familiaris) digestion [GO:0007586]; proteolysis [GO:0006508] GO:0004252; GO:0005615; GO:0006508; GO:0007586 8201 XM_044308324.1 136 99 57 97 126 NA NA NA NA NA NA 8202 XM_029343290.2 140 200 51 112 11 NA NA NA NA NA NA 8203 XM_044306998.1 0 0 28 0 0 NA NA NA NA NA NA 8204 XM_029326502.2 682 657 293 851 716 Q5U1V9 6.82e-34 Tetraspanin-31 (Tspan-31) (Sarcoma-amplified sequence homolog) Rattus norvegicus (Rat) NA GO:0005886 8205 XM_044312952.1 62 23 14 43 27 Q8K3Z0 3.44e-28 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 8206 XM_029330486.2 18 113 29 118 190 NA NA NA NA NA NA 8207 XR_006397247.1 0 127 0 0 6 NA NA NA NA NA NA 8208 XM_044328046.1 15 11 39 15 10 NA NA NA NA NA NA 8209 XR_003825712.2 16 31 1 13 18 NA NA NA NA NA NA 8210 XM_029357447.2 3434 5595 1706 1466 922 Q96HU8 6.42e-32 GTP-binding protein Di-Ras2 (Distinct subgroup of the Ras family member 2) Homo sapiens (Human) signal transduction [GO:0007165] GO:0003924; GO:0005525; GO:0005886; GO:0007165; GO:0019003 8211 XM_044326504.1 0 78 0 0 0 Q15075 3.29e-50 Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2) Homo sapiens (Human) chemical synaptic transmission, postsynaptic [GO:0099565]; early endosome to late endosome transport [GO:0045022]; endocytosis [GO:0006897]; modulation by host of viral process [GO:0044788]; synaptic vesicle to endosome fusion [GO:0016189]; vesicle fusion [GO:0006906] GO:0005516; GO:0005545; GO:0005737; GO:0005769; GO:0005829; GO:0005969; GO:0006897; GO:0006906; GO:0008270; GO:0016020; GO:0016189; GO:0019897; GO:0030742; GO:0031901; GO:0042803; GO:0044308; GO:0044788; GO:0045022; GO:0070062; GO:0098685; GO:0098794; GO:0098978; GO:0099565 8212 XM_029331471.2 5893 12304 5609 11977 9178 Q6NRQ7 6e-95 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 (CTD phosphatase SSU72) (EC 3.1.3.16) Xenopus laevis (African clawed frog) mRNA processing [GO:0006397] GO:0005634; GO:0005737; GO:0006397; GO:0017018 8213 XM_029340871.2 318 274 47 242 268 Q2YDD1 1.1e-46 Centrosomal protein 43 (FGFR1 oncogene partner) Bos taurus (Bovine) cell projection organization [GO:0030030]; microtubule anchoring [GO:0034453] GO:0005737; GO:0005814; GO:0030030; GO:0034453; GO:0042995 8214 XM_044306971.1 946 683 413 1051 743 Q86X10 0 Ral GTPase-activating protein subunit beta (p170) Homo sapiens (Human) activation of GTPase activity [GO:0090630]; regulation of small GTPase mediated signal transduction [GO:0051056] GO:0005096; GO:0046982; GO:0051056; GO:0090630 8215 XM_029351734.2 18 0 45 9 0 NA NA NA NA NA NA 8216 XM_029347537.2 101 54 110 73 56 NA NA NA NA NA NA 8217 XM_029356608.2 3226 2513 1264 2459 2181 Q5T8I3 4e-61 EEIG family member 2 (EEIG2) Homo sapiens (Human) NA NA 8218 XM_044311270.1 0 0 0 0 8 NA NA NA NA NA NA 8219 XM_029347107.2 0 16 0 16 64 NA NA NA NA NA NA 8220 XR_006393049.1 0 0 0 17 6 NA NA NA NA NA NA 8221 XM_044316176.1 1617 681 601 1515 657 NA NA NA NA NA NA 8222 XM_044312834.1 13 19 20 31 37 Q96JM7 9.36e-117 Lethal(3)malignant brain tumor-like protein 3 (H-l(3)mbt-like protein 3) (L(3)mbt-like protein 3) (L3mbt-like 3) (MBT-1) Homo sapiens (Human) chromatin organization [GO:0006325]; erythrocyte maturation [GO:0043249]; granulocyte differentiation [GO:0030851]; macrophage differentiation [GO:0030225]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; regulation of DNA methylation-dependent heterochromatin formation [GO:0090308] GO:0003682; GO:0005634; GO:0005654; GO:0005730; GO:0006325; GO:0008270; GO:0030225; GO:0030851; GO:0042393; GO:0042802; GO:0043249; GO:0045892; GO:0090308; GO:0140034; GO:2000060 8223 XM_029343913.2 282 251 328 284 332 Q9UBN7 5.97e-24 Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-) Homo sapiens (Human) aggresome assembly [GO:0070842]; autophagy [GO:0006914]; axonal transport of mitochondrion [GO:0019896]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to misfolded protein [GO:0071218]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to topologically incorrect protein [GO:0035967]; cilium assembly [GO:0060271]; cilium disassembly [GO:0061523]; collateral sprouting [GO:0048668]; dendritic spine morphogenesis [GO:0060997]; epigenetic regulation of gene expression [GO:0040029]; histone deacetylation [GO:0016575]; Hsp90 deacetylation [GO:0070846]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of protein-containing complex disassembly [GO:0043242]; negative regulation of proteolysis [GO:0045861]; negative regulation of transcription by RNA polymerase II [GO:0000122]; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:0061734]; peptidyl-lysine deacetylation [GO:0034983]; polyubiquitinated misfolded protein transport [GO:0070845]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of hydrogen peroxide-mediated programmed cell death [GO:1901300]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of tubulin deacetylation [GO:0090044]; protein deacetylation [GO:0006476]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; protein-containing complex disassembly [GO:0032984]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of autophagy [GO:0010506]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of establishment of protein localization [GO:0070201]; regulation of fat cell differentiation [GO:0045598]; regulation of macroautophagy [GO:0016241]; regulation of microtubule-based movement [GO:0060632]; regulation of protein stability [GO:0031647]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]; response to dexamethasone [GO:0071548]; response to growth factor [GO:0070848]; response to immobilization stress [GO:0035902]; response to misfolded protein [GO:0051788]; tubulin deacetylation [GO:0090042]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] GO:0000118; GO:0000122; GO:0000209; GO:0000978; GO:0001222; GO:0001975; GO:0003779; GO:0004407; GO:0005634; GO:0005654; GO:0005737; GO:0005771; GO:0005813; GO:0005829; GO:0005874; GO:0005875; GO:0005901; GO:0006476; GO:0006515; GO:0006886; GO:0006914; GO:0007026; GO:0008013; GO:0008017; GO:0008270; GO:0010506; GO:0010634; GO:0010727; GO:0016234; GO:0016235; GO:0016241; GO:0016575; GO:0019896; GO:0019899; GO:0030424; GO:0030425; GO:0031252; GO:0031333; GO:0031593; GO:0031625; GO:0031647; GO:0031648; GO:0032418; GO:0032984; GO:0033138; GO:0033558; GO:0034983; GO:0035902; GO:0035967; GO:0036064; GO:0040029; GO:0042826; GO:0042903; GO:0043014; GO:0043130; GO:0043162; GO:0043204; GO:0043242; GO:0045598; GO:0045861; GO:0045892; GO:0048156; GO:0048471; GO:0048487; GO:0048668; GO:0048843; GO:0050775; GO:0051354; GO:0051412; GO:0051787; GO:0051788; GO:0051879; GO:0051968; GO:0060271; GO:0060632; GO:0060765; GO:0060997; GO:0061523; GO:0061734; GO:0070201; GO:0070301; GO:0070840; GO:0070842; GO:0070845; GO:0070846; GO:0070848; GO:0071218; GO:0071374; GO:0071548; GO:0090042; GO:0090044; GO:1901300; GO:1901984; GO:1903146; GO:1903223; GO:1904056; GO:1904115; GO:2000273 8224 XM_044311318.1 868 689 434 837 700 Q96G03 2.27e-94 Phosphopentomutase (EC 5.4.2.7) (Glucose phosphomutase 2) (Phosphodeoxyribomutase) (Phosphoglucomutase-2) (EC 5.4.2.2) Homo sapiens (Human) glucose metabolic process [GO:0006006]; glycogen catabolic process [GO:0005980]; purine ribonucleoside salvage [GO:0006166] GO:0000287; GO:0004614; GO:0005576; GO:0005829; GO:0005980; GO:0006006; GO:0006166; GO:0008973; GO:0034774; GO:0070062; GO:1904813 8225 XR_006394928.1 26 16 28 4 22 NA NA NA NA NA NA 8226 XM_044324600.1 130 9 70 103 126 NA NA NA NA NA NA 8227 XM_029333946.2 31 1 43 39 12 NA NA NA NA NA NA 8228 XM_044323420.1 3 0 9 17 5 NA NA NA NA NA NA 8229 XM_044322217.1 10495 3818 4685 15421 6423 B3EWZ4 3.55e-37 Secreted acidic protein 2 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 8230 XM_029353993.2 0 17 5 0 0 Q09811 5.6e-27 ATP-dependent DNA helicase hus2/rqh1 (EC 3.6.4.12) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) cellular response to DNA damage stimulus [GO:0006974]; DNA double-strand break processing [GO:0000729]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724]; maintenance of rDNA [GO:0043007]; mitotic intra-S DNA damage checkpoint signaling [GO:0031573]; mitotic recombination-dependent replication fork processing [GO:1990426]; postreplication repair [GO:0006301]; recombinational repair [GO:0000725]; regulation of mitotic recombination-dependent replication fork processing [GO:1903221]; replication fork processing [GO:0031297]; resolution of mitotic recombination intermediates [GO:0071140]; UV-damage excision repair [GO:0070914] GO:0000228; GO:0000724; GO:0000725; GO:0000729; GO:0003677; GO:0005524; GO:0005634; GO:0005694; GO:0005730; GO:0005737; GO:0006268; GO:0006281; GO:0006301; GO:0006310; GO:0006974; GO:0009378; GO:0016887; GO:0031297; GO:0031422; GO:0031573; GO:0032508; GO:0035861; GO:0043007; GO:0043138; GO:0043596; GO:0070914; GO:0071140; GO:1903221; GO:1990426 8231 XR_003826858.2 1 11 9 3 5 NA NA NA NA NA NA 8232 XM_044311289.1 143 0 76 12 257 NA NA NA NA NA NA 8233 XR_006391936.1 24 115 81 140 85 NA NA NA NA NA NA 8234 XM_029355345.2 120 0 76 0 352 O15439 0 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 8235 XM_029349869.2 678 359 290 510 125 P50211 4.61e-123 Insulin gene enhancer protein ISL-1 (Islet-1) Gallus gallus (Chicken) atrial septum morphogenesis [GO:0060413]; axonogenesis [GO:0007409]; canonical Wnt signaling pathway [GO:0060070]; cardiac cell fate determination [GO:0060913]; cardiac muscle cell myoblast differentiation [GO:0060379]; cardiac right ventricle morphogenesis [GO:0003215]; cell population proliferation [GO:0008283]; endocardial cushion morphogenesis [GO:0003203]; heart development [GO:0007507]; innervation [GO:0060384]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural crest cell migration [GO:0001755]; neuron fate specification [GO:0048665]; outflow tract septum morphogenesis [GO:0003148]; pancreas development [GO:0031016]; peripheral nervous system neuron axonogenesis [GO:0048936]; pharyngeal system development [GO:0060037]; pituitary gland development [GO:0021983]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA binding [GO:0043388]; positive regulation of granulocyte colony-stimulating factor production [GO:0071657]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of histone acetylation [GO:0035066]; positive regulation of insulin secretion [GO:0032024]; positive regulation of interleukin-1 alpha production [GO:0032730]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type II interferon production [GO:0032729]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of secondary heart field cardioblast proliferation [GO:0003266]; regulation of transcription by RNA polymerase II [GO:0006357]; retinal ganglion cell axon guidance [GO:0031290]; secondary heart field specification [GO:0003139]; sensory system development [GO:0048880]; sinoatrial node cell development [GO:0060931]; spinal cord motor neuron cell fate specification [GO:0021520]; transcription by RNA polymerase II [GO:0006366]; trigeminal nerve development [GO:0021559]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; visceral motor neuron differentiation [GO:0021524] GO:0000122; GO:0000785; GO:0000978; GO:0000981; GO:0000987; GO:0001228; GO:0001755; GO:0003139; GO:0003148; GO:0003203; GO:0003215; GO:0003266; GO:0005634; GO:0006357; GO:0006366; GO:0007409; GO:0007507; GO:0008283; GO:0008284; GO:0010575; GO:0021520; GO:0021524; GO:0021559; GO:0021983; GO:0031016; GO:0031290; GO:0032024; GO:0032725; GO:0032729; GO:0032730; GO:0032731; GO:0032735; GO:0032755; GO:0032760; GO:0035066; GO:0042531; GO:0043388; GO:0043425; GO:0043524; GO:0045597; GO:0045665; GO:0045766; GO:0045892; GO:0045944; GO:0046872; GO:0048665; GO:0048880; GO:0048936; GO:0050728; GO:0055010; GO:0060037; GO:0060070; GO:0060379; GO:0060384; GO:0060413; GO:0060913; GO:0060931; GO:0061629; GO:0071657; GO:0086091; GO:0090090; GO:1990841 8236 XM_044312265.1 3 41 7 22 36 NA NA NA NA NA NA 8237 XR_006395492.1 887 658 510 1149 873 NA NA NA NA NA NA 8238 XM_044308206.1 63 34 40 73 38 NA NA NA NA NA NA 8239 XM_044317095.1 409 0 290 366 0 P11531 0 Dystrophin Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; aging [GO:0007568]; cardiac muscle cell action potential [GO:0086001]; cardiac muscle contraction [GO:0060048]; cerebral cortex development [GO:0021987]; establishment of blood-nerve barrier [GO:0008065]; establishment of glial blood-brain barrier [GO:0060857]; muscle cell cellular homeostasis [GO:0046716]; muscle cell development [GO:0055001]; muscle organ development [GO:0007517]; myotube cell development [GO:0014904]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of peptidyl-cysteine S-nitrosylation [GO:1902083]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; neuron development [GO:0048666]; neuron projection morphogenesis [GO:0048812]; neurotransmitter receptor metabolic process [GO:0045213]; nucleus localization [GO:0051647]; olfactory nerve structural organization [GO:0021629]; peptide biosynthetic process [GO:0043043]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neuron projection development [GO:0010976]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; protein localization [GO:0008104]; protein-containing complex assembly [GO:0065003]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell cycle [GO:0051726]; regulation of cellular response to growth factor stimulus [GO:0090287]; regulation of DNA-templated transcription [GO:0006355]; regulation of gene expression [GO:0010468]; regulation of heart rate [GO:0002027]; regulation of membrane potential [GO:0042391]; regulation of muscle system process [GO:0090257]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of skeletal muscle contraction [GO:0014819]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; regulation of voltage-gated calcium channel activity [GO:1901385]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; response to muscle stretch [GO:0035994]; response to water deprivation [GO:0009414]; skeletal muscle tissue development [GO:0007519]; skeletal muscle tissue regeneration [GO:0043403] GO:0001954; GO:0002027; GO:0002162; GO:0003779; GO:0005178; GO:0005521; GO:0005634; GO:0005741; GO:0005794; GO:0005840; GO:0005883; GO:0005886; GO:0006355; GO:0007517; GO:0007519; GO:0007568; GO:0008065; GO:0008104; GO:0008270; GO:0008284; GO:0008307; GO:0009414; GO:0009986; GO:0010468; GO:0010880; GO:0010881; GO:0010976; GO:0014069; GO:0014809; GO:0014819; GO:0014894; GO:0014904; GO:0016010; GO:0017022; GO:0017166; GO:0021629; GO:0021987; GO:0030016; GO:0030018; GO:0030027; GO:0030036; GO:0030054; GO:0030055; GO:0030141; GO:0030165; GO:0030175; GO:0030424; GO:0030672; GO:0030864; GO:0031527; GO:0032991; GO:0033137; GO:0035994; GO:0042383; GO:0042391; GO:0042995; GO:0043005; GO:0043025; GO:0043034; GO:0043043; GO:0043403; GO:0044306; GO:0044877; GO:0045121; GO:0045202; GO:0045211; GO:0045213; GO:0045665; GO:0045666; GO:0046716; GO:0048471; GO:0048666; GO:0048812; GO:0050998; GO:0051015; GO:0051647; GO:0051726; GO:0055001; GO:0060048; GO:0060314; GO:0060857; GO:0065003; GO:0070373; GO:0086001; GO:0090257; GO:0090287; GO:0097449; GO:0099572; GO:0099617; GO:1901385; GO:1902083; GO:2000651 8240 XM_044317095.1 409 0 290 366 0 P11531 1.83e-36 Dystrophin Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; aging [GO:0007568]; cardiac muscle cell action potential [GO:0086001]; cardiac muscle contraction [GO:0060048]; cerebral cortex development [GO:0021987]; establishment of blood-nerve barrier [GO:0008065]; establishment of glial blood-brain barrier [GO:0060857]; muscle cell cellular homeostasis [GO:0046716]; muscle cell development [GO:0055001]; muscle organ development [GO:0007517]; myotube cell development [GO:0014904]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of peptidyl-cysteine S-nitrosylation [GO:1902083]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; neuron development [GO:0048666]; neuron projection morphogenesis [GO:0048812]; neurotransmitter receptor metabolic process [GO:0045213]; nucleus localization [GO:0051647]; olfactory nerve structural organization [GO:0021629]; peptide biosynthetic process [GO:0043043]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neuron projection development [GO:0010976]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; protein localization [GO:0008104]; protein-containing complex assembly [GO:0065003]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell cycle [GO:0051726]; regulation of cellular response to growth factor stimulus [GO:0090287]; regulation of DNA-templated transcription [GO:0006355]; regulation of gene expression [GO:0010468]; regulation of heart rate [GO:0002027]; regulation of membrane potential [GO:0042391]; regulation of muscle system process [GO:0090257]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of skeletal muscle contraction [GO:0014819]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; regulation of voltage-gated calcium channel activity [GO:1901385]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; response to muscle stretch [GO:0035994]; response to water deprivation [GO:0009414]; skeletal muscle tissue development [GO:0007519]; skeletal muscle tissue regeneration [GO:0043403] GO:0001954; GO:0002027; GO:0002162; GO:0003779; GO:0005178; GO:0005521; GO:0005634; GO:0005741; GO:0005794; GO:0005840; GO:0005883; GO:0005886; GO:0006355; GO:0007517; GO:0007519; GO:0007568; GO:0008065; GO:0008104; GO:0008270; GO:0008284; GO:0008307; GO:0009414; GO:0009986; GO:0010468; GO:0010880; GO:0010881; GO:0010976; GO:0014069; GO:0014809; GO:0014819; GO:0014894; GO:0014904; GO:0016010; GO:0017022; GO:0017166; GO:0021629; GO:0021987; GO:0030016; GO:0030018; GO:0030027; GO:0030036; GO:0030054; GO:0030055; GO:0030141; GO:0030165; GO:0030175; GO:0030424; GO:0030672; GO:0030864; GO:0031527; GO:0032991; GO:0033137; GO:0035994; GO:0042383; GO:0042391; GO:0042995; GO:0043005; GO:0043025; GO:0043034; GO:0043043; GO:0043403; GO:0044306; GO:0044877; GO:0045121; GO:0045202; GO:0045211; GO:0045213; GO:0045665; GO:0045666; GO:0046716; GO:0048471; GO:0048666; GO:0048812; GO:0050998; GO:0051015; GO:0051647; GO:0051726; GO:0055001; GO:0060048; GO:0060314; GO:0060857; GO:0065003; GO:0070373; GO:0086001; GO:0090257; GO:0090287; GO:0097449; GO:0099572; GO:0099617; GO:1901385; GO:1902083; GO:2000651 8241 XM_044324653.1 42 20 2 0 37 NA NA NA NA NA NA 8242 XM_029327334.2 3496 1667 2255 1616 3063 P10079 1.26e-82 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 8243 XM_029327334.2 3496 1667 2255 1616 3063 P10079 1.78e-62 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 8244 XM_029327334.2 3496 1667 2255 1616 3063 P10079 1.57e-31 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 8245 XM_029339272.2 1394 195 1088 2657 710 P53454 1.18e-43 D(5)-like dopamine receptor Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) regulation of biological quality [GO:0065008] GO:0004930; GO:0005886; GO:0065008 8246 XM_029353904.2 2324 2797 2962 3740 3196 NA NA NA NA NA NA 8247 XR_003823879.2 32 2 46 34 104 NA NA NA NA NA NA 8248 XM_044311042.1 13 11 13 37 0 NA NA NA NA NA NA 8249 XM_044318350.1 0 9 1 1 15 NA NA NA NA NA NA 8250 XM_029335910.2 1361 1351 883 1699 1282 NA NA NA NA NA NA 8251 XM_029338371.2 34 0 0 39 16 Q9NQG7 7.42e-21 BLOC-3 complex member HPS4 (Hermansky-Pudlak syndrome 4 protein) (Light-ear protein homolog) Homo sapiens (Human) blood coagulation [GO:0007596]; hemostasis [GO:0007599]; intracellular transport [GO:0046907]; lysosome organization [GO:0007040]; melanocyte differentiation [GO:0030318]; melanosome assembly [GO:1903232]; platelet dense granule organization [GO:0060155]; positive regulation of eye pigmentation [GO:0048075]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein stabilization [GO:0050821]; protein targeting [GO:0006605]; vesicle-mediated transport [GO:0016192] GO:0005085; GO:0005737; GO:0005764; GO:0005765; GO:0005829; GO:0006605; GO:0007040; GO:0007596; GO:0007599; GO:0016020; GO:0016192; GO:0030318; GO:0031085; GO:0031267; GO:0031410; GO:0042470; GO:0042803; GO:0042827; GO:0046907; GO:0046983; GO:0048075; GO:0050821; GO:0060155; GO:1903232; GO:1903955 8252 XR_003828492.2 2514 3612 1741 2172 2123 NA NA NA NA NA NA 8253 XM_044319826.1 43 59 73 1 45 P97288 3.7e-36 5-hydroxytryptamine receptor 4 (5-HT-4) (5-HT4) (Serotonin receptor 4) Mus musculus (Mouse) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting serotonin receptor signaling pathway [GO:0007198]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; gamma-aminobutyric acid signaling pathway [GO:0007214]; regulation of appetite [GO:0032098] GO:0004993; GO:0005737; GO:0005768; GO:0005886; GO:0007187; GO:0007189; GO:0007198; GO:0007214; GO:0007268; GO:0016020; GO:0030425; GO:0030594; GO:0032098; GO:0045202; GO:0051378 8254 XM_029345840.2 6466 5168 5835 5262 2496 A7RVK7 4.3e-68 Probable trafficking protein particle complex subunit 2 Nematostella vectensis (Starlet sea anemone) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888] GO:0005634; GO:0005737; GO:0005783; GO:0006888; GO:0030008; GO:0048471; GO:1990071; GO:1990072 8255 XM_029351159.2 3167 3196 1993 2730 1096 NA NA NA NA NA NA 8256 XM_044312741.1 1857 876 704 1308 9 NA NA NA NA NA NA 8257 XM_029352292.2 1283 973 689 1103 1027 P15178 0 Aspartate--tRNA ligase, cytoplasmic (EC 6.1.1.12) (Aspartyl-tRNA synthetase) (AspRS) Rattus norvegicus (Rat) aspartyl-tRNA aminoacylation [GO:0006422] GO:0003723; GO:0004815; GO:0005524; GO:0005737; GO:0005829; GO:0006422; GO:0017101; GO:0045202 8258 XR_006398166.1 0 0 10 2 0 NA NA NA NA NA NA 8259 XR_006397122.1 110 74 46 78 191 P02469 1.29e-32 Laminin subunit beta-1 (Laminin B1 chain) (Laminin-1 subunit beta) (Laminin-10 subunit beta) (Laminin-12 subunit beta) (Laminin-2 subunit beta) (Laminin-6 subunit beta) (Laminin-8 subunit beta) Mus musculus (Mouse) animal organ morphogenesis [GO:0009887]; basement membrane assembly [GO:0070831]; cell migration [GO:0016477]; embryo implantation [GO:0007566]; learning or memory [GO:0007611]; negative regulation of cell adhesion [GO:0007162]; neuron projection development [GO:0031175]; neuronal-glial interaction involved in cerebral cortex radial glia guided migration [GO:0021812]; odontogenesis [GO:0042476]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of muscle cell differentiation [GO:0051149]; regulation of basement membrane organization [GO:0110011]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888] GO:0005178; GO:0005201; GO:0005576; GO:0005604; GO:0005606; GO:0005607; GO:0005615; GO:0005634; GO:0007162; GO:0007566; GO:0007611; GO:0009887; GO:0009888; GO:0016477; GO:0019899; GO:0021812; GO:0030335; GO:0031012; GO:0031175; GO:0034446; GO:0042476; GO:0043208; GO:0043256; GO:0043257; GO:0043259; GO:0045785; GO:0048471; GO:0051149; GO:0062023; GO:0070831; GO:0098637; GO:0110011; GO:2001046 8260 XR_006392197.1 0 0 0 0 11 NA NA NA NA NA NA 8261 XM_044323021.1 181 678 67 4142 3597 P02466 4.62e-46 Collagen alpha-2(I) chain (Alpha-2 type I collagen) Rattus norvegicus (Rat) blood vessel development [GO:0001568]; bone mineralization [GO:0030282]; cellular response to amino acid stimulus [GO:0071230]; cellular response to organic substance [GO:0071310]; cellular response to retinoic acid [GO:0071300]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; extracellular matrix assembly [GO:0085029]; extracellular matrix organization [GO:0030198]; protein heterotrimerization [GO:0070208]; regulation of blood pressure [GO:0008217]; response to norepinephrine [GO:0071873]; Rho protein signal transduction [GO:0007266]; skeletal system development [GO:0001501]; skin morphogenesis [GO:0043589]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001501; GO:0001568; GO:0002020; GO:0005201; GO:0005576; GO:0005581; GO:0005584; GO:0005615; GO:0007179; GO:0007266; GO:0008217; GO:0030198; GO:0030199; GO:0030282; GO:0030674; GO:0031012; GO:0032963; GO:0042802; GO:0043589; GO:0046332; GO:0046872; GO:0048407; GO:0062023; GO:0070208; GO:0071230; GO:0071300; GO:0071310; GO:0071873; GO:0085029; GO:0097067 8262 XM_044312787.1 51 0 10 111 0 P45954 0 Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial (SBCAD) (EC 1.3.8.5) (2-methyl branched chain acyl-CoA dehydrogenase) (2-MEBCAD) (2-methylbutyryl-coenzyme A dehydrogenase) (2-methylbutyryl-CoA dehydrogenase) Homo sapiens (Human) fatty acid metabolic process [GO:0006631]; isoleucine catabolic process [GO:0006550] GO:0003853; GO:0003995; GO:0005739; GO:0005759; GO:0006550; GO:0006631; GO:0016937; GO:0042802; GO:0050660; GO:0102035 8263 XM_044325302.1 17 1 13 32 16 NA NA NA NA NA NA 8264 XM_044311206.1 0 4 3 19 4 NA NA NA NA NA NA 8265 XM_044323971.1 0 7 5 9 3 NA NA NA NA NA NA 8266 XM_029330553.2 452 620 209 327 353 Q9CPX9 4.79e-42 Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11) Mus musculus (Mouse) anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell cycle [GO:0007049]; cell division [GO:0051301]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; protein K11-linked ubiquitination [GO:0070979]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004842; GO:0005634; GO:0005654; GO:0005680; GO:0005730; GO:0005737; GO:0006511; GO:0007049; GO:0008270; GO:0016567; GO:0031145; GO:0031461; GO:0034450; GO:0045842; GO:0051301; GO:0061630; GO:0070979; GO:0097602 8267 XM_044310738.1 6 1 2 7 0 B3EWZ5 6.21e-85 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8268 XM_044310738.1 6 1 2 7 0 B3EWZ5 2.91e-84 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8269 XM_044310738.1 6 1 2 7 0 B3EWZ5 1.17e-77 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8270 XM_044310738.1 6 1 2 7 0 B3EWZ5 6.48e-76 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8271 XM_044310738.1 6 1 2 7 0 B3EWZ5 1.43e-75 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8272 XM_044310738.1 6 1 2 7 0 B3EWZ5 3.26e-75 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8273 XM_044310738.1 6 1 2 7 0 B3EWZ5 1.64e-74 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8274 XM_044310738.1 6 1 2 7 0 B3EWZ5 3.54e-74 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8275 XM_044310738.1 6 1 2 7 0 B3EWZ5 3.25e-73 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8276 XM_044310738.1 6 1 2 7 0 B3EWZ5 1.91e-71 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8277 XM_044310738.1 6 1 2 7 0 B3EWZ5 8.12e-63 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8278 XM_044310738.1 6 1 2 7 0 B3EWZ5 1.74e-60 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8279 XM_044310738.1 6 1 2 7 0 B3EWZ5 4.84e-59 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8280 XM_044310738.1 6 1 2 7 0 B3EWZ5 3.24e-53 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8281 XM_044310738.1 6 1 2 7 0 B3EWZ5 2.06e-52 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8282 XM_044310738.1 6 1 2 7 0 B3EWZ5 1.33e-40 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8283 XM_044310738.1 6 1 2 7 0 B3EWZ5 1.78e-36 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 8284 XM_029333309.2 29 6 26 14 36 NA NA NA NA NA NA 8285 XM_029356920.2 15 18 16 53 23 NA NA NA NA NA NA 8286 XR_003828266.2 64 50 44 68 108 NA NA NA NA NA NA 8287 XM_044309373.1 9 0 0 15 13 NA NA NA NA NA NA 8288 XM_044329113.1 207 71 105 109 239 NA NA NA NA NA NA 8289 XM_029340346.2 0 39 0 0 15 Q9R1C8 1.04e-22 5-hydroxytryptamine receptor 6 (5-HT-6) (5-HT6) (Serotonin receptor 6) Mus musculus (Mouse) cerebral cortex cell migration [GO:0021795]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; learning [GO:0007612]; long-term synaptic potentiation [GO:0060291]; negative regulation of acetylcholine secretion, neurotransmission [GO:0014058]; negative regulation of gamma-aminobutyric acid secretion [GO:0014053]; negative regulation of glutamate secretion [GO:0014050]; positive regulation of dopamine secretion [GO:0033603]; positive regulation of gamma-aminobutyric acid secretion [GO:0014054]; positive regulation of TOR signaling [GO:0032008] GO:0004993; GO:0005886; GO:0005929; GO:0007187; GO:0007268; GO:0007612; GO:0014050; GO:0014053; GO:0014054; GO:0014058; GO:0021795; GO:0030425; GO:0030594; GO:0032008; GO:0033603; GO:0045202; GO:0060291 8290 XM_044315750.1 170 83 74 141 456 NA NA NA NA NA NA 8291 XM_044321614.1 209 191 86 227 239 NA NA NA NA NA NA 8292 XM_029334330.2 198 337 208 473 147 NA NA NA NA NA NA 8293 XM_044323676.1 0 18 9 4 67 NA NA NA NA NA NA 8294 XR_003823652.2 8 2 0 4 36 NA NA NA NA NA NA 8295 XM_044329017.1 91 238 91 134 196 NA NA NA NA NA NA 8296 XM_029340706.2 73 81 52 0 80 Q9NQX0 1.63e-89 Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.361) (PR domain zinc finger protein 6) (PR domain-containing protein 6) Homo sapiens (Human) chromatin organization [GO:0006325]; histone methylation [GO:0016571]; negative regulation of smooth muscle cell differentiation [GO:0051151]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of gene expression [GO:0010468] GO:0000122; GO:0005634; GO:0006325; GO:0010468; GO:0016571; GO:0022008; GO:0042802; GO:0046872; GO:0051151; GO:0140944 8297 XM_029323405.2 90 18 0 60 41 NA NA NA NA NA NA 8298 XM_044310345.1 7427 5800 2549 4171 2114 P20825 3.79e-75 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 8299 XM_029328978.2 787 655 509 680 1076 Q2YMB3 1.32e-52 Na(+)/H(+) antiporter NhaA (Sodium/proton antiporter NhaA) Brucella abortus (strain 2308) proteolysis [GO:0006508]; regulation of pH [GO:0006885] GO:0005886; GO:0006508; GO:0006885; GO:0008233; GO:0015081; GO:0015297 8300 XR_006395242.1 114 78 74 23 62 NA NA NA NA NA NA 8301 XM_029336689.2 296 153 165 392 384 P70699 0 Lysosomal alpha-glucosidase (EC 3.2.1.20) (Acid maltase) Mus musculus (Mouse) cardiac muscle contraction [GO:0060048]; diaphragm contraction [GO:0002086]; glycogen catabolic process [GO:0005980]; glycogen metabolic process [GO:0005977]; glycophagy [GO:0061723]; heart morphogenesis [GO:0003007]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; muscle cell cellular homeostasis [GO:0046716]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; regulation of the force of heart contraction [GO:0002026]; striated muscle contraction [GO:0006941]; tissue development [GO:0009888]; vacuolar sequestering [GO:0043181] GO:0002026; GO:0002086; GO:0003007; GO:0004553; GO:0004558; GO:0005764; GO:0005765; GO:0005977; GO:0005980; GO:0006941; GO:0007040; GO:0007626; GO:0009888; GO:0016020; GO:0030246; GO:0032450; GO:0043181; GO:0043231; GO:0043896; GO:0046716; GO:0050884; GO:0050885; GO:0060048; GO:0061723; GO:0090599; GO:0120282 8302 XM_044325907.1 29 0 3 8 0 P10665 3.03e-34 Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (p90-RSK) Xenopus laevis (African clawed frog) intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468] GO:0000287; GO:0004674; GO:0005524; GO:0006468; GO:0035556; GO:0106310 8303 XM_044307107.1 63 67 25 37 80 NA NA NA NA NA NA 8304 XM_044308571.1 24 48 27 33 11 NA NA NA NA NA NA 8305 XM_044306811.1 294 274 283 244 50 Q640S1 7.93e-63 Zinc transporter ZIP9 (Solute carrier family 39 member 9) (Zrt- and Irt-like protein 9) (ZIP-9) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) bicellular tight junction assembly [GO:0070830]; cellular zinc ion homeostasis [GO:0006882]; regulation of cellular response to testosterone stimulus [GO:2000654]; regulation of vascular endothelial cell proliferation [GO:1905562]; zinc ion transmembrane transport [GO:0071577] GO:0004930; GO:0005385; GO:0005497; GO:0005634; GO:0005739; GO:0005802; GO:0005886; GO:0006882; GO:0022883; GO:0031966; GO:0048471; GO:0070830; GO:0071577; GO:1905562; GO:2000654 8306 XM_044320394.1 0 0 581 1563 658 NA NA NA NA NA NA 8307 XR_003823997.2 8 6 7 41 40 NA NA NA NA NA NA 8308 XM_044314704.1 36 32 19 14 121 NA NA NA NA NA NA 8309 XR_006394754.1 1415 542 149 729 606 NA NA NA NA NA NA 8310 XM_029324167.2 2895 2636 1886 3835 3414 NA NA NA NA NA NA 8311 XM_044307662.1 451 759 435 261 215 NA NA NA NA NA NA 8312 XR_006397970.1 31 41 43 37 12 NA NA NA NA NA NA 8313 XM_029340691.2 280 195 200 249 91 A4FUY7 9.32e-59 Molybdopterin synthase catalytic subunit (EC 2.8.1.12) (Molybdenum cofactor synthesis protein 2 large subunit) (Molybdenum cofactor synthesis protein 2B) (MOCS2B) Bos taurus (Bovine) Mo-molybdopterin cofactor biosynthetic process [GO:0006777] GO:0005829; GO:0006777; GO:0016607; GO:0019008; GO:0030366 8314 XM_044308442.1 283 300 155 172 190 NA NA NA NA NA NA 8315 XM_044308934.1 261 233 127 382 547 P41041 1.28e-28 Calmodulin (CaM) Pneumocystis carinii NA GO:0005509 8316 XR_006393572.1 94 44 63 102 174 P48442 3.08e-84 Extracellular calcium-sensing receptor (CaSR) (Parathyroid cell calcium-sensing receptor) (PCaR1) (RaKCaR) Rattus norvegicus (Rat) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; apoptotic process [GO:0006915]; bile acid secretion [GO:0032782]; branching morphogenesis of an epithelial tube [GO:0048754]; calcium ion import [GO:0070509]; cellular calcium ion homeostasis [GO:0006874]; cellular response to glucose stimulus [GO:0071333]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hypoxia [GO:0071456]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to peptide [GO:1901653]; cellular response to vitamin D [GO:0071305]; chloride transmembrane transport [GO:1902476]; detection of calcium ion [GO:0005513]; fat pad development [GO:0060613]; G protein-coupled receptor signaling pathway [GO:0007186]; JNK cascade [GO:0007254]; ossification [GO:0001503]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of ATP-dependent activity [GO:0032781]; positive regulation of calcium ion import [GO:0090280]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin secretion [GO:0032024]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of vasoconstriction [GO:0045907]; regulation of calcium ion transport [GO:0051924]; response to calcium ion [GO:0051592]; response to fibroblast growth factor [GO:0071774]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to organic cyclic compound [GO:0014070]; vasodilation [GO:0042311] GO:0001503; GO:0002931; GO:0004930; GO:0005178; GO:0005509; GO:0005513; GO:0005634; GO:0005737; GO:0005886; GO:0006874; GO:0006915; GO:0007186; GO:0007193; GO:0007200; GO:0007254; GO:0008284; GO:0009986; GO:0010038; GO:0010628; GO:0014070; GO:0016020; GO:0016323; GO:0016324; GO:0016597; GO:0019901; GO:0030424; GO:0032024; GO:0032781; GO:0032782; GO:0035729; GO:0042311; GO:0042803; GO:0043005; GO:0043025; GO:0043679; GO:0044325; GO:0045907; GO:0048754; GO:0050927; GO:0051592; GO:0051924; GO:0060613; GO:0070374; GO:0070509; GO:0071305; GO:0071333; GO:0071404; GO:0071456; GO:0071774; GO:0090280; GO:1901653; GO:1902476 8317 XR_006393572.1 94 44 63 102 174 P48442 3.08e-84 Extracellular calcium-sensing receptor (CaSR) (Parathyroid cell calcium-sensing receptor) (PCaR1) (RaKCaR) Rattus norvegicus (Rat) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; apoptotic process [GO:0006915]; bile acid secretion [GO:0032782]; branching morphogenesis of an epithelial tube [GO:0048754]; calcium ion import [GO:0070509]; cellular calcium ion homeostasis [GO:0006874]; cellular response to glucose stimulus [GO:0071333]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hypoxia [GO:0071456]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to peptide [GO:1901653]; cellular response to vitamin D [GO:0071305]; chloride transmembrane transport [GO:1902476]; detection of calcium ion [GO:0005513]; fat pad development [GO:0060613]; G protein-coupled receptor signaling pathway [GO:0007186]; JNK cascade [GO:0007254]; ossification [GO:0001503]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of ATP-dependent activity [GO:0032781]; positive regulation of calcium ion import [GO:0090280]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin secretion [GO:0032024]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of vasoconstriction [GO:0045907]; regulation of calcium ion transport [GO:0051924]; response to calcium ion [GO:0051592]; response to fibroblast growth factor [GO:0071774]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to organic cyclic compound [GO:0014070]; vasodilation [GO:0042311] GO:0001503; GO:0002931; GO:0004930; GO:0005178; GO:0005509; GO:0005513; GO:0005634; GO:0005737; GO:0005886; GO:0006874; GO:0006915; GO:0007186; GO:0007193; GO:0007200; GO:0007254; GO:0008284; GO:0009986; GO:0010038; GO:0010628; GO:0014070; GO:0016020; GO:0016323; GO:0016324; GO:0016597; GO:0019901; GO:0030424; GO:0032024; GO:0032781; GO:0032782; GO:0035729; GO:0042311; GO:0042803; GO:0043005; GO:0043025; GO:0043679; GO:0044325; GO:0045907; GO:0048754; GO:0050927; GO:0051592; GO:0051924; GO:0060613; GO:0070374; GO:0070509; GO:0071305; GO:0071333; GO:0071404; GO:0071456; GO:0071774; GO:0090280; GO:1901653; GO:1902476 8318 XM_029328509.2 2530 1703 1419 2938 2165 NA NA NA NA NA NA 8319 XM_029335147.2 532 542 633 390 492 NA NA NA NA NA NA 8320 XM_044322884.1 146 108 134 372 335 Q96RW7 5.41e-70 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 8321 XM_044322884.1 146 108 134 372 335 Q96RW7 3.18e-69 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 8322 XM_044322884.1 146 108 134 372 335 Q96RW7 1.06e-66 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 8323 XM_044322884.1 146 108 134 372 335 Q96RW7 2e-48 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 8324 XM_029334531.2 219 128 182 115 126 P22727 4.73e-95 Protein Wnt-6 Mus musculus (Mouse) animal organ morphogenesis [GO:0009887]; axis specification [GO:0009798]; branching involved in ureteric bud morphogenesis [GO:0001658]; canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; cell-cell signaling [GO:0007267]; epithelial-mesenchymal cell signaling [GO:0060684]; nephron tubule development [GO:0072080]; nephron tubule formation [GO:0072079]; neuron differentiation [GO:0030182]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of tooth mineralization [GO:0070172]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055] GO:0001658; GO:0005102; GO:0005109; GO:0005125; GO:0005615; GO:0005788; GO:0007165; GO:0007267; GO:0009798; GO:0009887; GO:0009986; GO:0010628; GO:0016055; GO:0030182; GO:0031012; GO:0042475; GO:0045165; GO:0045893; GO:0060070; GO:0060684; GO:0070172; GO:0072079; GO:0072080 8325 XM_044325105.1 53 40 26 84 47 NA NA NA NA NA NA 8326 XM_029344761.2 13 0 0 0 26 NA NA NA NA NA NA 8327 XM_044316330.1 486 831 8 244 445 NA NA NA NA NA NA 8328 XM_029330606.2 65 99 13 1632 287 NA NA NA NA NA NA 8329 XR_006397267.1 55 45 3 13 27 NA NA NA NA NA NA 8330 XM_044317918.1 14723 11257 10368 12524 10833 NA NA NA NA NA NA 8331 XM_044324068.1 10 1 25 0 14 NA NA NA NA NA NA 8332 XM_044320749.1 0 0 0 0 8 NA NA NA NA NA NA 8333 XM_044322017.1 717 468 631 1328 953 NA NA NA NA NA NA 8334 XR_006395303.1 92 40 13 11 63 Q9BUZ4 8.03e-32 TNF receptor-associated factor 4 (EC 2.3.2.27) (Cysteine-rich domain associated with RING and Traf domains protein 1) (Metastatic lymph node gene 62 protein) (MLN 62) (RING finger protein 83) Homo sapiens (Human) activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; innate immune response [GO:0045087]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein kinase activity [GO:0045860]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; respiratory gaseous exchange by respiratory system [GO:0007585]; respiratory tube development [GO:0030323] GO:0001650; GO:0005164; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0005923; GO:0006915; GO:0007250; GO:0007585; GO:0008270; GO:0016740; GO:0019901; GO:0030323; GO:0031625; GO:0031996; GO:0042802; GO:0042981; GO:0043122; GO:0043161; GO:0045087; GO:0045860; GO:0046330; GO:0048471; GO:0050699 8335 XM_044312864.1 0 0 0 16 0 NA NA NA NA NA NA 8336 XM_044310222.1 3 35 30 15 0 NA NA NA NA NA NA 8337 XM_044325660.1 146 42 96 41 92 Q28EM8 1.77e-35 LETM1 domain-containing protein 1 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) mitochondrion organization [GO:0007005] GO:0005741; GO:0005743; GO:0007005; GO:0043022 8338 XM_029347732.2 4514 4201 2950 4539 3593 Q8IXF0 3.32e-86 Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Basic-helix-loop-helix-PAS protein MOP6) (Class E basic helix-loop-helix protein 12) (bHLHe12) (Member of PAS protein 6) (PAS domain-containing protein 6) Homo sapiens (Human) positive regulation of DNA-templated transcription [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000785; GO:0000977; GO:0000981; GO:0005654; GO:0006357; GO:0045893; GO:0046982 8339 XR_006395105.1 58 74 25 41 40 Q76KP1 1.6e-59 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Homo sapiens (Human) NA GO:0008376; GO:0032580; GO:0033842 8340 XR_006395105.1 58 74 25 41 40 Q76KP1 4.33e-22 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Homo sapiens (Human) NA GO:0008376; GO:0032580; GO:0033842 8341 XR_006395105.1 58 74 25 41 40 Q76KP1 4.33e-22 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Homo sapiens (Human) NA GO:0008376; GO:0032580; GO:0033842 8342 XM_029357820.2 0 4 10 13 17 Q6DIV6 3.6e-73 Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Solute carrier family 32 member 1) (Vesicular GABA transporter) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) beta-alanine transport [GO:0001762]; gamma-aminobutyric acid import [GO:0051939]; gamma-aminobutyric acid transport [GO:0015812]; glycine transport [GO:0015816]; neurotransmitter transport [GO:0006836] GO:0001762; GO:0006836; GO:0008021; GO:0015185; GO:0015187; GO:0015812; GO:0015816; GO:0030659; GO:0042995; GO:0051939; GO:0098793; GO:0140799; GO:0140800 8343 XM_044326554.1 0 1 0 10 20 NA NA NA NA NA NA 8344 XM_029343141.2 395 181 204 176 267 Q41745 4.51e-74 1-acyl-sn-glycerol-3-phosphate acyltransferase PLS1 (EC 2.3.1.51) (Phospholipid synthesis protein 1) Zea mays (Maize) CDP-diacylglycerol biosynthetic process [GO:0016024] GO:0003841; GO:0012505; GO:0016020; GO:0016024; GO:0016746 8345 XM_029338650.2 10 7 14 1 92 NA NA NA NA NA NA 8346 XM_029355418.2 1505 1386 923 933 1037 NA NA NA NA NA NA 8347 XM_029343063.2 0 0 0 40 18 P54833 2.75e-24 Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor) Canis lupus familiaris (Dog) (Canis familiaris) activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; desensitization of G protein-coupled receptor signaling pathway by arrestin [GO:0002032]; negative regulation of smooth muscle contraction [GO:0045986]; norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0002025]; positive regulation of autophagosome maturation [GO:1901098]; positive regulation of lipophagy [GO:1904504]; positive regulation of MAPK cascade [GO:0043410]; receptor-mediated endocytosis [GO:0006898] GO:0002025; GO:0002032; GO:0004930; GO:0004941; GO:0005769; GO:0005794; GO:0005886; GO:0006898; GO:0007190; GO:0042803; GO:0043235; GO:0043410; GO:0045986; GO:0051380; GO:0071880; GO:1901098; GO:1904504 8348 XM_029348071.2 0 0 0 0 56 NA NA NA NA NA NA 8349 XM_044324679.1 496 740 331 365 368 NA NA NA NA NA NA 8350 XM_029353428.2 8 11 2 59 16 NA NA NA NA NA NA 8351 XM_029343101.2 9 0 0 23 0 NA NA NA NA NA NA 8352 XM_029340961.2 341 389 150 385 225 Q9CR24 5.4e-47 Mitochondrial coenzyme A diphosphatase NUDT8 (EC 3.6.1.-) (Nucleoside diphosphate-linked moiety X motif 8) (Nudix motif 8) Mus musculus (Mouse) acetyl-CoA catabolic process [GO:0046356]; butyryl-CoA catabolic process [GO:0044580]; coenzyme A catabolic process [GO:0015938]; malonyl-CoA catabolic process [GO:2001294]; medium-chain fatty-acyl-CoA catabolic process [GO:0036114]; propionyl-CoA catabolic process [GO:1902859]; succinyl-CoA catabolic process [GO:1901289] GO:0000287; GO:0005739; GO:0010945; GO:0015938; GO:0030145; GO:0036114; GO:0044580; GO:0046356; GO:0106399; GO:1901289; GO:1902859; GO:2001294 8353 XR_003825334.2 32 13 21 31 171 NA NA NA NA NA NA 8354 XM_029331558.2 721 623 693 655 336 NA NA NA NA NA NA 8355 XR_006398121.1 130 201 85 265 252 NA NA NA NA NA NA 8356 XM_029334587.2 32 11 22 37 6 NA NA NA NA NA NA 8357 XM_029339620.2 239 143 152 151 287 Q5ZIZ2 4.59e-148 Histone-lysine N-trimethyltransferase SMYD5 (EC 2.1.1.372) (SET and MYND domain-containing protein 5) ([histone H4]-lysine20 N-trimethyltransferase SMYD5) Gallus gallus (Chicken) histone lysine methylation [GO:0034968]; negative regulation of gene expression, epigenetic [GO:0045814]; regulation of stem cell differentiation [GO:2000736]; regulation of stem cell division [GO:2000035] GO:0018024; GO:0034968; GO:0042799; GO:0045814; GO:0046872; GO:0140943; GO:2000035; GO:2000736 8358 XM_029331616.2 45 30 18 62 0 NA NA NA NA NA NA 8359 XM_044312296.1 0 0 0 0 10 NA NA NA NA NA NA 8360 XM_029334990.2 43 35 20 24 26 NA NA NA NA NA NA 8361 XR_006397165.1 424 222 208 269 270 P22770 2.63e-66 Neuronal acetylcholine receptor subunit alpha-7 Gallus gallus (Chicken) calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; cognition [GO:0050890]; membrane depolarization [GO:0051899]; negative regulation of tumor necrosis factor production [GO:0032720]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAPK cascade [GO:0043410]; regulation of nitric oxide metabolic process [GO:0080164]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; signal transduction [GO:0007165] GO:0001540; GO:0001666; GO:0005737; GO:0005886; GO:0005892; GO:0006816; GO:0006874; GO:0007165; GO:0008284; GO:0015464; GO:0015643; GO:0017081; GO:0022848; GO:0030424; GO:0030425; GO:0032720; GO:0035094; GO:0042166; GO:0042803; GO:0043204; GO:0043410; GO:0045211; GO:0045766; GO:0050890; GO:0051899; GO:0080164 8362 XM_044326521.1 43 0 0 0 0 NA NA NA NA NA NA 8363 XM_044313455.1 0 0 26 1 32 NA NA NA NA NA NA 8364 XM_029345985.2 156 80 35 41 31 NA NA NA NA NA NA 8365 XM_044308061.1 81 101 0 39 12 NA NA NA NA NA NA 8366 XR_006393971.1 6 0 0 0 5 NA NA NA NA NA NA 8367 XR_003826404.2 753 1340 309 1904 1216 NA NA NA NA NA NA 8368 XR_006392297.1 2188 298 296 679 1855 NA NA NA NA NA NA 8369 XR_006394621.1 45 23 21 23 37 NA NA NA NA NA NA 8370 XM_044315126.1 28 6 3 2 16 NA NA NA NA NA NA 8371 XM_029330449.2 804 596 422 761 543 Q3V096 1.84e-142 Ankyrin repeat domain-containing protein 42 Mus musculus (Mouse) positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of NF-kappaB transcription factor activity [GO:0051092] GO:0005634; GO:0051059; GO:0051091; GO:0051092; GO:1900017 8372 XM_029339883.2 60 206 615 0 80 Q6P0U3 2.68e-29 Ras-like protein family member 11B (EC 3.6.5.2) Danio rerio (Zebrafish) (Brachydanio rerio) mesendoderm development [GO:0048382] GO:0003925; GO:0005525; GO:0048382 8373 XM_044310080.1 11 7 0 1 52 NA NA NA NA NA NA 8374 XM_029332827.2 986 643 465 611 694 NA NA NA NA NA NA 8375 XM_029330252.2 630 441 353 340 626 O35857 1.37e-118 Mitochondrial import inner membrane translocase subunit TIM44 Mus musculus (Mouse) intracellular protein transport [GO:0006886]; protein import into mitochondrial matrix [GO:0030150] GO:0001650; GO:0005524; GO:0005739; GO:0005743; GO:0005759; GO:0006886; GO:0019899; GO:0030150; GO:0051087 8376 XM_029335965.2 438 396 260 270 324 NA NA NA NA NA NA 8377 XM_029342302.2 72 113 60 63 96 NA NA NA NA NA NA 8378 XM_029331121.2 201 181 122 501 306 NA NA NA NA NA NA 8379 XM_029331542.2 1247 850 856 673 633 Q7Q107 1.72e-85 Mediator of RNA polymerase II transcription subunit 6 (Mediator complex subunit 6) Anopheles gambiae (African malaria mosquito) regulation of transcription by RNA polymerase II [GO:0006357] GO:0003713; GO:0006357; GO:0016592; GO:0070847 8380 XM_044318246.1 116 86 71 437 371 Q9HAR2 3.98e-70 Adhesion G protein-coupled receptor L3 (Calcium-independent alpha-latrotoxin receptor 3) (CIRL-3) (Latrophilin-3) (Lectomedin-3) Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; brain development [GO:0007420]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; G protein-coupled receptor signaling pathway [GO:0007186]; neuron migration [GO:0001764]; synapse assembly [GO:0007416] GO:0001764; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007166; GO:0007186; GO:0007189; GO:0007416; GO:0007420; GO:0016020; GO:0030246; GO:0030424; GO:0098742; GO:0098978 8381 XM_044315615.1 149 35 168 44 363 NA NA NA NA NA NA 8382 XM_044311234.1 4 20 24 1 19 NA NA NA NA NA NA 8383 XM_029346930.2 2532 1622 1262 2300 1957 G3C7W6 4.97e-146 NA NA NA NA 8384 XM_029346930.2 2532 1622 1262 2300 1957 G3C7W6 6.09e-53 NA NA NA NA 8385 XM_044310044.1 9 74 18 85 0 Q28824 1.77e-74 Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form] Bos taurus (Bovine) protein phosphorylation [GO:0006468]; tonic smooth muscle contraction [GO:0014820] GO:0001725; GO:0003779; GO:0004672; GO:0004687; GO:0005516; GO:0005524; GO:0005737; GO:0006468; GO:0014820; GO:0030027; GO:0032154; GO:0046872 8386 XM_029331424.2 119 118 113 183 156 NA NA NA NA NA NA 8387 XM_044321953.1 0 0 65 0 0 NA NA NA NA NA NA 8388 XM_044306836.1 74 19 111 193 51 Q8N0P0 2.47e-33 Octopine dehydrogenase (OcDH) (EC 1.5.1.11) Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis) NA GO:0047830 8389 XM_029332357.2 26 11 25 16 19 NA NA NA NA NA NA 8390 XM_044311888.1 21 0 0 25 0 NA NA NA NA NA NA 8391 XM_044310117.1 78 0 30 104 0 NA NA NA NA NA NA 8392 XM_044314231.1 22 0 24 3 222 Q8BR93 3.23e-24 Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease) Mus musculus (Mouse) NA GO:0004518; GO:0005634; GO:0005829; GO:0005886; GO:0034451; GO:0046872 8393 XM_029354056.2 145 80 110 310 437 Q9UI42 3.44e-75 Carboxypeptidase A4 (EC 3.4.17.-) (Carboxypeptidase A3) Homo sapiens (Human) histone acetylation [GO:0016573]; proteolysis [GO:0006508] GO:0004181; GO:0005615; GO:0006508; GO:0008270; GO:0016573 8394 XM_044307505.1 291 398 104 393 123 NA NA NA NA NA NA 8395 XM_044326355.1 95 94 140 20 36 NA NA NA NA NA NA 8396 XM_044317342.1 0 38 0 0 13 Q8TC07 2.59e-33 TBC1 domain family member 15 (GTPase-activating protein RAB7) (GAP for RAB7) (Rab7-GAP) Homo sapiens (Human) activation of GTPase activity [GO:0090630]; regulation of GTPase activity [GO:0043087] GO:0005096; GO:0005576; GO:0005737; GO:0043087; GO:0090630 8397 XM_044322803.1 60 0 59 38 3 Q13591 1.09e-71 Semaphorin-5A (Semaphorin-F) (Sema F) Homo sapiens (Human) axon extension [GO:0048675]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell-cell signaling [GO:0007267]; diencephalon development [GO:0021536]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of cell adhesion [GO:0007162]; negative regulation of endothelial cell apoptotic process [GO:2000352]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; positive chemotaxis [GO:0050918]; positive regulation of actin filament depolymerization [GO:0030836]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein kinase B signaling [GO:0051897]; semaphorin-plexin signaling pathway [GO:0071526]; signal clustering [GO:1990256] GO:0001755; GO:0001938; GO:0002043; GO:0005886; GO:0007155; GO:0007162; GO:0007267; GO:0007399; GO:0007411; GO:0007413; GO:0016020; GO:0021536; GO:0030215; GO:0030335; GO:0030836; GO:0035373; GO:0043395; GO:0045499; GO:0045545; GO:0045766; GO:0048675; GO:0048842; GO:0048843; GO:0050918; GO:0051897; GO:0060326; GO:0070062; GO:0071526; GO:0090263; GO:1990256; GO:2000352; GO:2001028 8398 XM_029325829.2 0 0 51 0 0 NA NA NA NA NA NA 8399 XR_006393337.1 0 0 0 18 0 NA NA NA NA NA NA 8400 XM_029331631.2 124 105 5 16 0 NA NA NA NA NA NA 8401 XR_003825575.2 23 21 0 5 33 NA NA NA NA NA NA 8402 XR_006394591.1 268 83 194 197 504 NA NA NA NA NA NA 8403 XM_044328363.1 113 111 5 61 16 Q9Y5N5 5.48e-72 Methyltransferase N6AMT1 (HemK methyltransferase family member 2) (M.HsaHemK2P) (Lysine N-methyltransferase 9) (EC 2.1.1.-) (Methylarsonite methyltransferase N6AMT1) (EC 2.1.1.-) (Protein N(5)-glutamine methyltransferase) (EC 2.1.1.-) Homo sapiens (Human) arsonoacetate metabolic process [GO:0018872]; chromatin organization [GO:0006325]; DNA methylation on adenine [GO:0032775]; histone lysine methylation [GO:0034968]; methylation [GO:0032259]; peptidyl-glutamine methylation [GO:0018364]; positive regulation of cell growth [GO:0030307]; toxin metabolic process [GO:0009404] GO:0003676; GO:0005634; GO:0005829; GO:0006325; GO:0008276; GO:0008757; GO:0009007; GO:0009404; GO:0018024; GO:0018364; GO:0018872; GO:0030307; GO:0030792; GO:0032259; GO:0032775; GO:0032991; GO:0034968; GO:0035657; GO:0036009; GO:1904047 8404 XM_029332297.2 3650 2361 1897 3243 2501 Q66JZ4 5.11e-65 T-cell activation inhibitor, mitochondrial (Tolerance associated gene-1 protein) (TOAG-1) Mus musculus (Mouse) NA GO:0005739 8405 XR_006392524.1 19 22 18 17 29 NA NA NA NA NA NA 8406 XM_044318746.1 45 64 16 24 32 Q766D5 4.31e-61 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Mus musculus (Mouse) chondroitin sulfate biosynthetic process [GO:0030206] GO:0008376; GO:0030206; GO:0032580; GO:0033842; GO:0047238 8407 XM_044318746.1 45 64 16 24 32 Q766D5 4.92e-26 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Mus musculus (Mouse) chondroitin sulfate biosynthetic process [GO:0030206] GO:0008376; GO:0030206; GO:0032580; GO:0033842; GO:0047238 8408 XM_029342655.2 361 328 143 250 140 Q9R0N9 7.37e-44 Synaptotagmin-9 (Synaptotagmin IX) (SytIX) (Synaptotagmin V) Mus musculus (Mouse) calcium-dependent activation of synaptic vesicle fusion [GO:0099502]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of insulin secretion [GO:0050796]; vesicle-mediated transport [GO:0016192] GO:0000149; GO:0001786; GO:0005509; GO:0005544; GO:0005546; GO:0005886; GO:0014059; GO:0016192; GO:0017156; GO:0017158; GO:0019905; GO:0030141; GO:0030276; GO:0030667; GO:0030672; GO:0031045; GO:0042802; GO:0045956; GO:0050796; GO:0070382; GO:0071277; GO:0098686; GO:0099502 8409 XM_029339449.2 14 24 13 21 21 Q96DM1 2.09e-76 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 8410 XM_029353388.2 7 5 13 10 28 NA NA NA NA NA NA 8411 XR_003825454.2 15 22 13 17 49 NA NA NA NA NA NA 8412 XM_044328424.1 0 66 119 46 193 NA NA NA NA NA NA 8413 XR_006391405.1 0 4 0 11 0 NA NA NA NA NA NA 8414 XM_044324105.1 83 7 57 17 80 NA NA NA NA NA NA 8415 XM_029333667.2 2952 2720 2834 6065 6349 NA NA NA NA NA NA 8416 XM_029355536.2 104 398 128 245 220 Q4R6P2 1.39e-67 RWD domain-containing protein 2A Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA NA 8417 XM_029342456.2 65 60 104 98 63 Q9GRC0 2e-77 Serine/threonine-protein kinase mos (EC 2.7.11.1) (Oocyte maturation factor mos) Patiria pectinifera (Starfish) (Asterina pectinifera) female gamete generation [GO:0007292]; female meiosis II [GO:0007147]; negative regulation of mitotic cell cycle [GO:0045930]; protein phosphorylation [GO:0006468] GO:0004709; GO:0005524; GO:0006468; GO:0007147; GO:0007292; GO:0045930; GO:0106310 8418 XM_044324435.1 142 22 8 161 63 NA NA NA NA NA NA 8419 XM_029326632.2 1512 1777 1106 742 462 B0UYI1 1.38e-45 Transcription elongation factor A N-terminal and central domain-containing protein 2 Danio rerio (Zebrafish) (Brachydanio rerio) DNA-templated transcription [GO:0006351] GO:0005634; GO:0006351 8420 XR_006391721.1 0 0 15 0 86 NA NA NA NA NA NA 8421 XM_044313328.1 88 37 27 29 65 NA NA NA NA NA NA 8422 XM_044321484.1 406 43 2 322 59 Q01804 1.99e-71 OTU domain-containing protein 4 (EC 3.4.19.12) (HIV-1-induced protein HIN-1) Homo sapiens (Human) innate immune response [GO:0045087]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; positive regulation of DNA demethylation [GO:1901537]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; regulation of protein K48-linked deubiquitination [GO:1903093] GO:0003723; GO:0004843; GO:0005634; GO:0005829; GO:0016579; GO:0034122; GO:0045087; GO:0060090; GO:0061578; GO:0070536; GO:0071108; GO:1901537; GO:1903093; GO:2000660 8423 XM_044328141.1 214 106 206 462 303 NA NA NA NA NA NA 8424 XM_044327238.1 0 25 0 0 77 Q90481 1.63e-34 Homeobox protein Nkx-2.2a (Homeobox protein NK-2 homolog B-A) Danio rerio (Zebrafish) (Brachydanio rerio) cell differentiation [GO:0030154]; endocrine pancreas development [GO:0031018]; floor plate development [GO:0033504]; floor plate formation [GO:0021508]; glial cell migration [GO:0008347]; motor neuron axon guidance [GO:0008045]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357]; Schwann cell development [GO:0014044]; spinal cord oligodendrocyte cell differentiation [GO:0021529]; spinal cord oligodendrocyte cell fate specification [GO:0021530]; ventral spinal cord interneuron differentiation [GO:0021514] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0008045; GO:0008347; GO:0014044; GO:0021508; GO:0021514; GO:0021529; GO:0021530; GO:0030154; GO:0031018; GO:0033504; GO:0045893 8425 XM_044320168.1 636 150 248 38 242 Q9ULJ7 2.06e-46 Ankyrin repeat domain-containing protein 50 Homo sapiens (Human) endocytic recycling [GO:0032456]; protein transport [GO:0015031] GO:0005768; GO:0015031; GO:0032456 8426 XM_044328485.1 0 14 0 8 27 Q6NU40 0 Chromosome transmission fidelity protein 18 homolog Xenopus laevis (African clawed frog) cell cycle [GO:0007049]; DNA replication [GO:0006260] GO:0003677; GO:0003689; GO:0005524; GO:0005634; GO:0005663; GO:0006260; GO:0007049; GO:0016887 8427 XM_044327185.1 415 296 172 459 439 NA NA NA NA NA NA 8428 XM_044329269.1 27 47 21 9 21 NA NA NA NA NA NA 8429 XR_006397731.1 128 49 82 114 82 NA NA NA NA NA NA 8430 XM_044313515.1 600 502 684 807 835 Q8R1A4 0 Dedicator of cytokinesis protein 7 (Protein moonlight) Mus musculus (Mouse) activation of GTPase activity [GO:0090630]; axonogenesis [GO:0007409]; establishment of neuroblast polarity [GO:0045200]; hematopoietic progenitor cell differentiation [GO:0002244]; interkinetic nuclear migration [GO:0022027]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of cold-induced thermogenesis [GO:0120163]; neuron projection development [GO:0031175]; pigmentation [GO:0043473]; positive regulation of GTPase activity [GO:0043547]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; postsynaptic specialization assembly [GO:0098698]; regulation of neurogenesis [GO:0050767]; small GTPase mediated signal transduction [GO:0007264] GO:0000226; GO:0002244; GO:0005085; GO:0007264; GO:0007409; GO:0008180; GO:0022027; GO:0030424; GO:0031175; GO:0031267; GO:0031594; GO:0033138; GO:0043473; GO:0043547; GO:0045200; GO:0050767; GO:0090630; GO:0098698; GO:0120163; GO:1904754 8431 XM_029324139.2 1054 1317 1084 3131 1837 NA NA NA NA NA NA 8432 XM_044318838.1 285 206 111 254 62 NA NA NA NA NA NA 8433 XM_044321399.1 64 37 15 91 87 Q5U3Y0 8.93e-98 Kelch domain-containing protein 10 Rattus norvegicus (Rat) positive regulation of stress-activated MAPK cascade [GO:0032874]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process via the C-end degron rule pathway [GO:0140627] GO:0005634; GO:0005737; GO:0016567; GO:0031462; GO:0032874; GO:0140627; GO:1990756 8434 XM_029326605.2 15 43 40 29 0 Q49LS8 2.92e-28 XK-related protein 6 Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon nigroviridis) NA GO:0005886 8435 XM_029328948.2 1780 1460 478 1749 1420 P43404 5.65e-83 Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-chain associated protein) (Syk-related tyrosine kinase) Mus musculus (Mouse) adaptive immune response [GO:0002250]; alpha-beta T cell differentiation [GO:0046632]; beta selection [GO:0043366]; calcium-mediated signaling [GO:0019722]; cell differentiation [GO:0030154]; immune response [GO:0006955]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; negative thymic T cell selection [GO:0045060]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of T cell differentiation [GO:0045582]; positive thymic T cell selection [GO:0045059]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; thymic T cell selection [GO:0045061]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0001772; GO:0001784; GO:0002250; GO:0004672; GO:0004713; GO:0004715; GO:0005102; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0005911; GO:0006468; GO:0006955; GO:0007169; GO:0016020; GO:0018108; GO:0019722; GO:0030154; GO:0030217; GO:0031234; GO:0035556; GO:0042101; GO:0043366; GO:0045059; GO:0045060; GO:0045061; GO:0045087; GO:0045121; GO:0045582; GO:0046632; GO:0046638; GO:0046641; GO:0046777; GO:0050850; GO:0050852 8436 XM_029328948.2 1780 1460 478 1749 1420 P43404 3.91e-39 Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-chain associated protein) (Syk-related tyrosine kinase) Mus musculus (Mouse) adaptive immune response [GO:0002250]; alpha-beta T cell differentiation [GO:0046632]; beta selection [GO:0043366]; calcium-mediated signaling [GO:0019722]; cell differentiation [GO:0030154]; immune response [GO:0006955]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; negative thymic T cell selection [GO:0045060]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of T cell differentiation [GO:0045582]; positive thymic T cell selection [GO:0045059]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; thymic T cell selection [GO:0045061]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0001772; GO:0001784; GO:0002250; GO:0004672; GO:0004713; GO:0004715; GO:0005102; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0005911; GO:0006468; GO:0006955; GO:0007169; GO:0016020; GO:0018108; GO:0019722; GO:0030154; GO:0030217; GO:0031234; GO:0035556; GO:0042101; GO:0043366; GO:0045059; GO:0045060; GO:0045061; GO:0045087; GO:0045121; GO:0045582; GO:0046632; GO:0046638; GO:0046641; GO:0046777; GO:0050850; GO:0050852 8437 XM_029341973.2 3204 2183 1908 4836 4288 Q8N5H7 3.01e-29 SH2 domain-containing protein 3C (Cas/HEF1-associated signal transducer) (Chat-H) (Novel SH2-containing protein 3) (SH2 domain-containing Eph receptor-binding protein 1) (SHEP1) Homo sapiens (Human) JNK cascade [GO:0007254]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; small GTPase mediated signal transduction [GO:0007264] GO:0001784; GO:0005085; GO:0005829; GO:0007254; GO:0007264; GO:0030424; GO:0032587; GO:0033138 8438 XM_029330093.2 246 451 159 326 293 NA NA NA NA NA NA 8439 XM_029343102.2 0 1 13 0 0 NA NA NA NA NA NA 8440 XR_006394931.1 0 0 10 23 0 NA NA NA NA NA NA 8441 XM_044327813.1 0 2 14 0 0 NA NA NA NA NA NA 8442 XM_029349689.2 1604 1184 1173 1562 1715 Q5R5X0 7.61e-43 Pinin Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0003677; GO:0005681; GO:0006397; GO:0008380; GO:0016607; GO:0030057 8443 XM_044322857.1 754 269 230 421 566 NA NA NA NA NA NA 8444 XM_029352597.2 0 0 0 0 296 Q8N8E3 0 Centrosomal protein of 112 kDa (Cep112) (Coiled-coil domain-containing protein 46) Homo sapiens (Human) receptor localization to synapse [GO:0097120] GO:0005737; GO:0005813; GO:0005886; GO:0060077; GO:0097120 8445 XR_006395997.1 6 0 4 26 0 Q9W5Y0 1.56e-115 Neprilysin-3 (EC 3.4.24.11) Drosophila melanogaster (Fruit fly) peptide hormone processing [GO:0016486]; protein processing [GO:0016485]; proteolysis [GO:0006508] GO:0004222; GO:0005886; GO:0006508; GO:0008237; GO:0016020; GO:0016485; GO:0016486; GO:0046872 8446 XM_029355854.2 635 580 474 483 253 Q9VAI1 5.83e-32 Complex I intermediate-associated protein 30, mitochondrial Drosophila melanogaster (Fruit fly) mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrial respiratory chain complex I assembly [GO:0032981]; mitochondrion organization [GO:0007005]; NADH dehydrogenase complex assembly [GO:0010257]; response to heat [GO:0009408]; response to hyperoxia [GO:0055093]; response to hypoxia [GO:0001666]; response to starvation [GO:0042594] GO:0001666; GO:0005739; GO:0006120; GO:0007005; GO:0009408; GO:0010257; GO:0032981; GO:0042594; GO:0051082; GO:0055093; GO:1990204 8447 XM_044316910.1 0 0 0 108 45 O75899 5.53e-115 Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51) (HG20) Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway [GO:0007186]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; neuron-glial cell signaling [GO:0150099]; synaptic transmission, GABAergic [GO:0051932] GO:0004888; GO:0004965; GO:0005737; GO:0005886; GO:0007186; GO:0007193; GO:0007194; GO:0007214; GO:0007268; GO:0038039; GO:0043005; GO:0045211; GO:0046982; GO:0051932; GO:0150099; GO:1902710; GO:1902712 8448 XM_029355816.2 0 0 17 23 83 R1CW23 5.09e-109 Dimethylsulfonioproprionate lyase 7 (DMSP lyase 7) (EC 4.4.1.3) (Dimethylpropiothetin dethiomethylase 7) Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi) NA GO:0047869 8449 XM_044326016.1 2232 2317 1632 2336 2477 Q01484 0 Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin) Homo sapiens (Human) atrial cardiac muscle cell action potential [GO:0086014]; atrial cardiac muscle cell to AV node cell communication [GO:0086066]; atrial septum development [GO:0003283]; cellular calcium ion homeostasis [GO:0006874]; endocytosis [GO:0006897]; membrane depolarization during SA node cell action potential [GO:0086046]; paranodal junction assembly [GO:0030913]; positive regulation of calcium ion transmembrane transporter activity [GO:1901021]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cation channel activity [GO:2001259]; positive regulation of gene expression [GO:0010628]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to endoplasmic reticulum [GO:0070972]; protein localization to M-band [GO:0036309]; protein localization to organelle [GO:0033365]; protein localization to plasma membrane [GO:0072659]; protein localization to T-tubule [GO:0036371]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; regulation of atrial cardiac muscle cell action potential [GO:0098910]; regulation of calcium ion transmembrane transporter activity [GO:1901019]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of heart rate [GO:0002027]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of protein stability [GO:0031647]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of SA node cell action potential [GO:0098907]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; response to methylmercury [GO:0051597]; SA node cell action potential [GO:0086015]; SA node cell to atrial cardiac muscle cell communication [GO:0086070]; sarcoplasmic reticulum calcium ion transport [GO:0070296]; T-tubule organization [GO:0033292]; ventricular cardiac muscle cell action potential [GO:0086005] GO:0002027; GO:0003283; GO:0005200; GO:0005739; GO:0005764; GO:0005769; GO:0005829; GO:0005856; GO:0005886; GO:0006874; GO:0006897; GO:0008093; GO:0008104; GO:0010628; GO:0010881; GO:0010882; GO:0014704; GO:0015031; GO:0016323; GO:0016324; GO:0019899; GO:0019901; GO:0030018; GO:0030315; GO:0030507; GO:0030674; GO:0030913; GO:0031430; GO:0031647; GO:0031672; GO:0033292; GO:0033365; GO:0034394; GO:0036309; GO:0036371; GO:0042383; GO:0043005; GO:0043034; GO:0043268; GO:0044325; GO:0045121; GO:0045211; GO:0050821; GO:0051117; GO:0051279; GO:0051597; GO:0051924; GO:0051928; GO:0055037; GO:0055117; GO:0060307; GO:0070296; GO:0070972; GO:0072659; GO:0086004; GO:0086005; GO:0086014; GO:0086015; GO:0086046; GO:0086066; GO:0086070; GO:0086091; GO:0098907; GO:0098910; GO:0140031; GO:1901018; GO:1901019; GO:1901021; GO:2001259 8450 XM_044326016.1 2232 2317 1632 2336 2477 Q01484 1e-105 Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin) Homo sapiens (Human) atrial cardiac muscle cell action potential [GO:0086014]; atrial cardiac muscle cell to AV node cell communication [GO:0086066]; atrial septum development [GO:0003283]; cellular calcium ion homeostasis [GO:0006874]; endocytosis [GO:0006897]; membrane depolarization during SA node cell action potential [GO:0086046]; paranodal junction assembly [GO:0030913]; positive regulation of calcium ion transmembrane transporter activity [GO:1901021]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cation channel activity [GO:2001259]; positive regulation of gene expression [GO:0010628]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to endoplasmic reticulum [GO:0070972]; protein localization to M-band [GO:0036309]; protein localization to organelle [GO:0033365]; protein localization to plasma membrane [GO:0072659]; protein localization to T-tubule [GO:0036371]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; regulation of atrial cardiac muscle cell action potential [GO:0098910]; regulation of calcium ion transmembrane transporter activity [GO:1901019]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of heart rate [GO:0002027]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of protein stability [GO:0031647]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of SA node cell action potential [GO:0098907]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; response to methylmercury [GO:0051597]; SA node cell action potential [GO:0086015]; SA node cell to atrial cardiac muscle cell communication [GO:0086070]; sarcoplasmic reticulum calcium ion transport [GO:0070296]; T-tubule organization [GO:0033292]; ventricular cardiac muscle cell action potential [GO:0086005] GO:0002027; GO:0003283; GO:0005200; GO:0005739; GO:0005764; GO:0005769; GO:0005829; GO:0005856; GO:0005886; GO:0006874; GO:0006897; GO:0008093; GO:0008104; GO:0010628; GO:0010881; GO:0010882; GO:0014704; GO:0015031; GO:0016323; GO:0016324; GO:0019899; GO:0019901; GO:0030018; GO:0030315; GO:0030507; GO:0030674; GO:0030913; GO:0031430; GO:0031647; GO:0031672; GO:0033292; GO:0033365; GO:0034394; GO:0036309; GO:0036371; GO:0042383; GO:0043005; GO:0043034; GO:0043268; GO:0044325; GO:0045121; GO:0045211; GO:0050821; GO:0051117; GO:0051279; GO:0051597; GO:0051924; GO:0051928; GO:0055037; GO:0055117; GO:0060307; GO:0070296; GO:0070972; GO:0072659; GO:0086004; GO:0086005; GO:0086014; GO:0086015; GO:0086046; GO:0086066; GO:0086070; GO:0086091; GO:0098907; GO:0098910; GO:0140031; GO:1901018; GO:1901019; GO:1901021; GO:2001259 8451 XM_044326016.1 2232 2317 1632 2336 2477 Q01484 9.57e-104 Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin) Homo sapiens (Human) atrial cardiac muscle cell action potential [GO:0086014]; atrial cardiac muscle cell to AV node cell communication [GO:0086066]; atrial septum development [GO:0003283]; cellular calcium ion homeostasis [GO:0006874]; endocytosis [GO:0006897]; membrane depolarization during SA node cell action potential [GO:0086046]; paranodal junction assembly [GO:0030913]; positive regulation of calcium ion transmembrane transporter activity [GO:1901021]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cation channel activity [GO:2001259]; positive regulation of gene expression [GO:0010628]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to endoplasmic reticulum [GO:0070972]; protein localization to M-band [GO:0036309]; protein localization to organelle [GO:0033365]; protein localization to plasma membrane [GO:0072659]; protein localization to T-tubule [GO:0036371]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; regulation of atrial cardiac muscle cell action potential [GO:0098910]; regulation of calcium ion transmembrane transporter activity [GO:1901019]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of heart rate [GO:0002027]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of protein stability [GO:0031647]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of SA node cell action potential [GO:0098907]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; response to methylmercury [GO:0051597]; SA node cell action potential [GO:0086015]; SA node cell to atrial cardiac muscle cell communication [GO:0086070]; sarcoplasmic reticulum calcium ion transport [GO:0070296]; T-tubule organization [GO:0033292]; ventricular cardiac muscle cell action potential [GO:0086005] GO:0002027; GO:0003283; GO:0005200; GO:0005739; GO:0005764; GO:0005769; GO:0005829; GO:0005856; GO:0005886; GO:0006874; GO:0006897; GO:0008093; GO:0008104; GO:0010628; GO:0010881; GO:0010882; GO:0014704; GO:0015031; GO:0016323; GO:0016324; GO:0019899; GO:0019901; GO:0030018; GO:0030315; GO:0030507; GO:0030674; GO:0030913; GO:0031430; GO:0031647; GO:0031672; GO:0033292; GO:0033365; GO:0034394; GO:0036309; GO:0036371; GO:0042383; GO:0043005; GO:0043034; GO:0043268; GO:0044325; GO:0045121; GO:0045211; GO:0050821; GO:0051117; GO:0051279; GO:0051597; GO:0051924; GO:0051928; GO:0055037; GO:0055117; GO:0060307; GO:0070296; GO:0070972; GO:0072659; GO:0086004; GO:0086005; GO:0086014; GO:0086015; GO:0086046; GO:0086066; GO:0086070; GO:0086091; GO:0098907; GO:0098910; GO:0140031; GO:1901018; GO:1901019; GO:1901021; GO:2001259 8452 XM_044326016.1 2232 2317 1632 2336 2477 Q01484 2.1e-47 Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin) Homo sapiens (Human) atrial cardiac muscle cell action potential [GO:0086014]; atrial cardiac muscle cell to AV node cell communication [GO:0086066]; atrial septum development [GO:0003283]; cellular calcium ion homeostasis [GO:0006874]; endocytosis [GO:0006897]; membrane depolarization during SA node cell action potential [GO:0086046]; paranodal junction assembly [GO:0030913]; positive regulation of calcium ion transmembrane transporter activity [GO:1901021]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cation channel activity [GO:2001259]; positive regulation of gene expression [GO:0010628]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to endoplasmic reticulum [GO:0070972]; protein localization to M-band [GO:0036309]; protein localization to organelle [GO:0033365]; protein localization to plasma membrane [GO:0072659]; protein localization to T-tubule [GO:0036371]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; regulation of atrial cardiac muscle cell action potential [GO:0098910]; regulation of calcium ion transmembrane transporter activity [GO:1901019]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of heart rate [GO:0002027]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of protein stability [GO:0031647]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of SA node cell action potential [GO:0098907]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; response to methylmercury [GO:0051597]; SA node cell action potential [GO:0086015]; SA node cell to atrial cardiac muscle cell communication [GO:0086070]; sarcoplasmic reticulum calcium ion transport [GO:0070296]; T-tubule organization [GO:0033292]; ventricular cardiac muscle cell action potential [GO:0086005] GO:0002027; GO:0003283; GO:0005200; GO:0005739; GO:0005764; GO:0005769; GO:0005829; GO:0005856; GO:0005886; GO:0006874; GO:0006897; GO:0008093; GO:0008104; GO:0010628; GO:0010881; GO:0010882; GO:0014704; GO:0015031; GO:0016323; GO:0016324; GO:0019899; GO:0019901; GO:0030018; GO:0030315; GO:0030507; GO:0030674; GO:0030913; GO:0031430; GO:0031647; GO:0031672; GO:0033292; GO:0033365; GO:0034394; GO:0036309; GO:0036371; GO:0042383; GO:0043005; GO:0043034; GO:0043268; GO:0044325; GO:0045121; GO:0045211; GO:0050821; GO:0051117; GO:0051279; GO:0051597; GO:0051924; GO:0051928; GO:0055037; GO:0055117; GO:0060307; GO:0070296; GO:0070972; GO:0072659; GO:0086004; GO:0086005; GO:0086014; GO:0086015; GO:0086046; GO:0086066; GO:0086070; GO:0086091; GO:0098907; GO:0098910; GO:0140031; GO:1901018; GO:1901019; GO:1901021; GO:2001259 8453 XM_044308184.1 187 0 0 110 33 Q9V9A7 1.38e-163 Probable methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCase subunit beta) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 2) (3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta) Drosophila melanogaster (Fruit fly) coenzyme A metabolic process [GO:0015936]; leucine catabolic process [GO:0006552]; regulation of eclosion [GO:0007563] GO:0004485; GO:0005524; GO:0005739; GO:0005759; GO:0006552; GO:0007563; GO:0015936; GO:1905202 8454 XM_044320819.1 17 2 3 2 36 NA NA NA NA NA NA 8455 XM_044316065.1 339 93 96 208 426 NA NA NA NA NA NA 8456 XM_044326561.1 192 1 183 216 291 NA NA NA NA NA NA 8457 XM_044317308.1 0 11 8 27 14 A0A2B4SES9 5.18e-111 NA NA NA NA 8458 XM_044320996.1 848 878 510 915 507 A6QLU6 1.66e-23 Adhesion G-protein coupled receptor D1 (G-protein coupled receptor 133) Bos taurus (Bovine) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0005886; GO:0007166; GO:0007186; GO:0007189 8459 XM_029338979.2 35 197 71 108 79 NA NA NA NA NA NA 8460 XM_044322912.1 1045 780 679 2292 1496 Q9DCD2 0 Pre-mRNA-splicing factor SYF1 (XPA-binding protein 2) Mus musculus (Mouse) blastocyst development [GO:0001824]; cerebral cortex development [GO:0021987]; DNA-templated transcription [GO:0006351]; generation of catalytic spliceosome for first transesterification step [GO:0000349]; mRNA splicing, via spliceosome [GO:0000398]; transcription-coupled nucleotide-excision repair [GO:0006283] GO:0000349; GO:0000398; GO:0000974; GO:0001824; GO:0005634; GO:0005654; GO:0006283; GO:0006351; GO:0021987; GO:0043231; GO:0071007; GO:0071013; GO:0071014 8461 XM_044306808.1 33 39 8 26 34 NA NA NA NA NA NA 8462 XM_029355847.2 62 22 183 292 77 Q5Y4N8 2.42e-72 Adhesion G protein-coupled receptor E2 (EGF-like module receptor 1) (EGF-like module-containing mucin-like hormone receptor-like 1) (EMR1 hormone receptor) Rattus norvegicus (Rat) adaptive immune response [GO:0002250]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cellular response to tumor necrosis factor [GO:0071356] GO:0002250; GO:0004930; GO:0005509; GO:0005886; GO:0007166; GO:0007189; GO:0009897; GO:0071356; GO:0071560; GO:0071944 8463 XM_029355847.2 62 22 183 292 77 Q5Y4N8 4.64e-24 Adhesion G protein-coupled receptor E2 (EGF-like module receptor 1) (EGF-like module-containing mucin-like hormone receptor-like 1) (EMR1 hormone receptor) Rattus norvegicus (Rat) adaptive immune response [GO:0002250]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cellular response to tumor necrosis factor [GO:0071356] GO:0002250; GO:0004930; GO:0005509; GO:0005886; GO:0007166; GO:0007189; GO:0009897; GO:0071356; GO:0071560; GO:0071944 8464 XM_029355092.2 128 0 19 41 162 NA NA NA NA NA NA 8465 XR_003827393.2 98 21 124 43 597 NA NA NA NA NA NA 8466 XM_029339538.2 370 214 174 134 242 P55345 4.96e-126 Protein arginine N-methyltransferase 2 (EC 2.1.1.319) (Histone-arginine N-methyltransferase PRMT2) Homo sapiens (Human) developmental cell growth [GO:0048588]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; peptidyl-arginine methylation [GO:0018216]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA-templated transcription [GO:0045893]; protein methylation [GO:0006479]; regulation of androgen receptor signaling pathway [GO:0060765]; signal transduction [GO:0007165] GO:0003713; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0006479; GO:0007165; GO:0008469; GO:0016274; GO:0018216; GO:0030331; GO:0032088; GO:0033142; GO:0035242; GO:0042054; GO:0042803; GO:0042974; GO:0042975; GO:0043065; GO:0044877; GO:0045892; GO:0045893; GO:0046966; GO:0048588; GO:0050681; GO:0060765; GO:0140592; GO:2000134 8467 XM_029347134.2 11073 12862 8938 4637 4599 NA NA NA NA NA NA 8468 XM_029327814.2 39 76 17 105 166 Q96DM1 3.66e-49 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 8469 XM_029345893.2 101 46 56 88 51 NA NA NA NA NA NA 8470 XM_044329013.1 19 9 22 2 108 NA NA NA NA NA NA 8471 XM_044316240.1 55 17 0 3 6 Q96PM5 1.51e-35 RING finger and CHY zinc finger domain-containing protein 1 (EC 2.3.2.27) (Androgen receptor N-terminal-interacting protein) (CH-rich-interacting match with PLAG1) (E3 ubiquitin-protein ligase Pirh2) (RING finger protein 199) (RING-type E3 ubiquitin transferase RCHY1) (Zinc finger protein 363) (p53-induced RING-H2 protein) (hPirh2) Homo sapiens (Human) error-free translesion synthesis [GO:0070987]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; protein autoubiquitination [GO:0051865]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000151; GO:0002039; GO:0004842; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006511; GO:0008270; GO:0016567; GO:0016607; GO:0031398; GO:0032436; GO:0042803; GO:0043231; GO:0051865; GO:0061630; GO:0070987 8472 XM_029340096.2 16 1 22 1 109 NA NA NA NA NA NA 8473 XM_044312269.1 1256 1685 1043 1837 1622 Q6P8C4 3.33e-51 H/ACA ribonucleoprotein complex subunit 2-like protein (Nucleolar protein family A member 2-like protein) (snoRNP protein NHP2-like protein) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) rRNA pseudouridine synthesis [GO:0031118]; telomere maintenance via telomerase [GO:0007004] GO:0003723; GO:0005697; GO:0005730; GO:0005732; GO:0007004; GO:0031118 8474 XM_029334521.2 145 52 0 0 340 NA NA NA NA NA NA 8475 XR_003824573.2 64 62 27 42 89 NA NA NA NA NA NA 8476 XM_029325123.2 1953 1154 1060 1435 1391 A0JMQ7 1.56e-21 Microtubule-associated tumor suppressor 1 homolog A (Mitochondrial tumor suppressor 1 homolog A) Danio rerio (Zebrafish) (Brachydanio rerio) cell cycle [GO:0007049] GO:0005634; GO:0005739; GO:0005794; GO:0005886; GO:0007049; GO:0008017 8477 XM_029340222.2 60 0 88 7 93 Q4VBS4 8.3e-103 Methionine aminopeptidase 1D, mitochondrial (MAP 1D) (MetAP 1D) (EC 3.4.11.18) (Methionyl aminopeptidase type 1D, mitochondrial) (Peptidase M 1D) Danio rerio (Zebrafish) (Brachydanio rerio) protein initiator methionine removal [GO:0070084]; proteolysis [GO:0006508] GO:0005739; GO:0006508; GO:0046872; GO:0070006; GO:0070084 8478 XM_044311695.1 23 0 86 7 171 Q96T58 8.74e-62 Msx2-interacting protein (SMART/HDAC1-associated repressor protein) (SPEN homolog) Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of neurogenesis [GO:0050769]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0003677; GO:0003714; GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0006357; GO:0007219; GO:0017053; GO:0045892; GO:0050769; GO:0061629; GO:0070062 8479 XM_044311695.1 23 0 86 7 171 Q96T58 6.59e-59 Msx2-interacting protein (SMART/HDAC1-associated repressor protein) (SPEN homolog) Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of neurogenesis [GO:0050769]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0003677; GO:0003714; GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0006357; GO:0007219; GO:0017053; GO:0045892; GO:0050769; GO:0061629; GO:0070062 8480 XM_029334050.2 231 98 106 191 317 Q61184 1.55e-22 Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor) Mus musculus (Mouse) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; circadian rhythm [GO:0007623]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of insulin secretion [GO:0046676] GO:0004930; GO:0005886; GO:0007186; GO:0007193; GO:0007623; GO:0008502; GO:0042562; GO:0043025; GO:0043235; GO:0046676; GO:0097159 8481 XM_044318184.1 58 0 28 100 88 NA NA NA NA NA NA 8482 XM_029346895.2 741 282 463 372 429 A8KBE0 1.46e-86 Oxidation resistance protein 1 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005739 8483 XM_029347990.2 41 143 35 401 599 P0CI65 3.91e-46 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 8484 XM_029347990.2 41 143 35 401 599 P0CI65 1.78e-41 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 8485 XM_029347990.2 41 143 35 401 599 P0CI65 2e-38 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 8486 XM_029347990.2 41 143 35 401 599 P0CI65 3.36e-36 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 8487 XM_029347990.2 41 143 35 401 599 P0CI65 5.77e-31 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 8488 XM_044315683.1 171 69 59 148 176 Q6PIW4 1.34e-175 Fidgetin-like protein 1 (EC 3.6.4.-) Homo sapiens (Human) ATP metabolic process [GO:0046034]; cellular response to ionizing radiation [GO:0071479]; male meiotic nuclear division [GO:0007140]; negative regulation of apoptotic process [GO:0043066]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; regulation of cell cycle [GO:0051726]; regulation of double-strand break repair via homologous recombination [GO:0010569] GO:0000228; GO:0000287; GO:0001649; GO:0005524; GO:0005634; GO:0005737; GO:0007140; GO:0008568; GO:0010569; GO:0016787; GO:0016887; GO:0033687; GO:0043066; GO:0046034; GO:0048471; GO:0051726; GO:0070062; GO:0071479; GO:2001243 8489 XM_029340772.2 609 568 789 895 822 O57382 1.76e-39 Tolloid-like protein 2 (EC 3.4.24.-) (Metalloprotease xolloid) (Xenopus tolloid) Xenopus laevis (African clawed frog) cell differentiation [GO:0030154]; proteolysis [GO:0006508] GO:0004222; GO:0005509; GO:0005576; GO:0006508; GO:0008270; GO:0030154 8490 XM_029340772.2 609 568 789 895 822 O57382 5.21e-37 Tolloid-like protein 2 (EC 3.4.24.-) (Metalloprotease xolloid) (Xenopus tolloid) Xenopus laevis (African clawed frog) cell differentiation [GO:0030154]; proteolysis [GO:0006508] GO:0004222; GO:0005509; GO:0005576; GO:0006508; GO:0008270; GO:0030154 8491 XM_029333066.2 18 0 0 18 0 NA NA NA NA NA NA 8492 XM_044326376.1 4642 4234 3002 3629 3183 NA NA NA NA NA NA 8493 XM_044308030.1 10 0 0 80 14 NA NA NA NA NA NA 8494 XM_044314536.1 87 60 105 0 279 NA NA NA NA NA NA 8495 XM_044319973.1 186 68 68 162 107 Q8R422 0 CD109 antigen (GPI-anchored alpha-2 macroglobulin-related protein) (CD antigen CD109) Mus musculus (Mouse) hair follicle development [GO:0001942]; keratinocyte proliferation [GO:0043616]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of peptidase activity [GO:0010466]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of stem cell proliferation [GO:2000647]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of wound healing [GO:0061045]; osteoclast fusion [GO:0072675]; protein phosphorylation [GO:0006468]; regulation of keratinocyte differentiation [GO:0045616]; stem cell proliferation [GO:0072089] GO:0001933; GO:0001942; GO:0004867; GO:0005615; GO:0005829; GO:0005886; GO:0006468; GO:0010466; GO:0010839; GO:0030512; GO:0043616; GO:0045616; GO:0050431; GO:0061045; GO:0072089; GO:0072675; GO:2000647 8496 XM_029350414.2 126 64 64 107 207 NA NA NA NA NA NA 8497 XM_029349579.2 682 748 405 924 543 Q9V6X7 1.15e-102 GDP-fucose protein O-fucosyltransferase 1 (EC 2.4.1.221) (Neurotic protein) (Peptide-O-fucosyltransferase 1) (O-FucT-1) Drosophila melanogaster (Fruit fly) cell fate commitment [GO:0045165]; fucose metabolic process [GO:0006004]; Notch signaling pathway [GO:0007219]; O-glycan processing [GO:0016266]; positive regulation of endocytosis [GO:0045807]; positive regulation of Notch signaling pathway [GO:0045747]; protein O-linked fucosylation [GO:0036066]; protein O-linked glycosylation [GO:0006493]; regulation of Notch signaling pathway [GO:0008593] GO:0005112; GO:0005783; GO:0006004; GO:0006493; GO:0007219; GO:0008417; GO:0008593; GO:0016266; GO:0036066; GO:0045165; GO:0045747; GO:0045807; GO:0046922 8498 XM_044307487.1 0 10 0 1 10 Q6PBX9 1.09e-32 Receptor expression-enhancing protein 5 Danio rerio (Zebrafish) (Brachydanio rerio) endoplasmic reticulum membrane organization [GO:0090158] GO:0033017; GO:0090158 8499 XM_044321543.1 49 64 30 21 13 NA NA NA NA NA NA 8500 XM_029338450.2 349 206 114 340 374 Q1JQC1 7.54e-42 Major facilitator superfamily domain-containing protein 1 Bos taurus (Bovine) protein localization to lysosome [GO:0061462]; protein stabilization [GO:0050821] GO:0005764; GO:0005765; GO:0022857; GO:0042803; GO:0050821; GO:0061462 8501 XM_044319576.1 9 12 2 12 34 Q9Z0T6 4.32e-53 Polycystin family receptor for egg jelly (PKD and REJ homolog) (Polycystic kidney disease and receptor for egg jelly-related protein) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982]; regulation of acrosome reaction [GO:0060046] GO:0005262; GO:0005509; GO:0016020; GO:0050982; GO:0060046; GO:0097524 8502 XM_044309834.1 0 0 0 254 15 Q29RU2 1.32e-35 Oncoprotein-induced transcript 3 protein Bos taurus (Bovine) NA GO:0005509; GO:0005635 8503 XM_029340356.2 31 0 32 93 98 Q9R1C8 3.96e-23 5-hydroxytryptamine receptor 6 (5-HT-6) (5-HT6) (Serotonin receptor 6) Mus musculus (Mouse) cerebral cortex cell migration [GO:0021795]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; learning [GO:0007612]; long-term synaptic potentiation [GO:0060291]; negative regulation of acetylcholine secretion, neurotransmission [GO:0014058]; negative regulation of gamma-aminobutyric acid secretion [GO:0014053]; negative regulation of glutamate secretion [GO:0014050]; positive regulation of dopamine secretion [GO:0033603]; positive regulation of gamma-aminobutyric acid secretion [GO:0014054]; positive regulation of TOR signaling [GO:0032008] GO:0004993; GO:0005886; GO:0005929; GO:0007187; GO:0007268; GO:0007612; GO:0014050; GO:0014053; GO:0014054; GO:0014058; GO:0021795; GO:0030425; GO:0030594; GO:0032008; GO:0033603; GO:0045202; GO:0060291 8504 XM_029332906.2 87 229 21 482 594 Q9ULI0 0 ATPase family AAA domain-containing protein 2B Homo sapiens (Human) positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0003682; GO:0005524; GO:0005634; GO:0005654; GO:0016887; GO:0042393; GO:0045944; GO:0070577 8505 XM_044319664.1 0 0 29 0 19 P30974 5.65e-31 Tachykinin-like peptides receptor 86C (NKD) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; inter-male aggressive behavior [GO:0002121]; neuropeptide signaling pathway [GO:0007218]; tachykinin receptor signaling pathway [GO:0007217] GO:0002121; GO:0004995; GO:0005886; GO:0007186; GO:0007217; GO:0007218; GO:0008188; GO:0016020 8506 XM_044323995.1 171 171 344 312 450 NA NA NA NA NA NA 8507 XM_029339446.2 838 499 466 601 784 O95671 1.41e-65 Probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein [Includes: dTTP/UTP pyrophosphatase (dTTPase/UTPase) (EC 3.6.1.9) (Nucleoside triphosphate pyrophosphatase) (Nucleotide pyrophosphatase) (Nucleotide PPase); N-acetylserotonin O-methyltransferase-like protein (ASMTL) (EC 2.1.1.-)] Homo sapiens (Human) methylation [GO:0032259]; nucleotide metabolic process [GO:0009117] GO:0005829; GO:0008171; GO:0009117; GO:0032259; GO:0036218; GO:0036221; GO:0047429 8508 XM_044324403.1 70 23 20 37 46 Q9NUU7 2.08e-40 ATP-dependent RNA helicase DDX19A (EC 3.6.4.13) (DDX19-like protein) (DEAD box protein 19A) Homo sapiens (Human) poly(A)+ mRNA export from nucleus [GO:0016973]; positive regulation of apoptotic process [GO:0043065]; response to zinc ion [GO:0010043] GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005654; GO:0010043; GO:0010494; GO:0016020; GO:0016887; GO:0016973; GO:0043065 8509 XM_044323740.1 121 38 106 43 209 NA NA NA NA NA NA 8510 XM_044310620.1 336 446 110 383 0 Q06546 1.14e-58 GA-binding protein alpha chain (GABP subunit alpha) (Nuclear respiratory factor 2 subunit alpha) (Transcription factor E4TF1-60) Homo sapiens (Human) blastocyst formation [GO:0001825]; cell differentiation [GO:0030154]; cellular response to dopamine [GO:1903351]; negative regulation of megakaryocyte differentiation [GO:0045653]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000785; GO:0000976; GO:0000978; GO:0000981; GO:0001228; GO:0001825; GO:0003682; GO:0003700; GO:0005634; GO:0005654; GO:0006357; GO:0010628; GO:0030154; GO:0045653; GO:0045944; GO:1903351; GO:1990837 8511 XM_029329672.2 190 21 83 134 169 Q5VU97 2.35e-84 VWFA and cache domain-containing protein 1 (Cache domain-containing protein 1) Homo sapiens (Human) NA GO:0005245; GO:0005891 8512 XM_029340578.2 1167 1223 792 974 986 Q7ZT48 1.11e-75 DNA replication complex GINS protein SLD5 (GINS complex subunit 4) Xenopus laevis (African clawed frog) DNA replication [GO:0006260]; DNA-templated DNA replication [GO:0006261] GO:0000811; GO:0003682; GO:0005634; GO:0005737; GO:0006260; GO:0006261; GO:0071162 8513 XM_044324776.1 0 0 0 0 28 NA NA NA NA NA NA 8514 XM_029342546.2 1013 1127 494 1134 753 Q08257 2.1e-125 Quinone oxidoreductase (EC 1.6.5.5) (NADPH:quinone reductase) (Zeta-crystallin) Homo sapiens (Human) protein homotetramerization [GO:0051289]; visual perception [GO:0007601]; xenobiotic catabolic process [GO:0042178] GO:0003730; GO:0003960; GO:0005829; GO:0007601; GO:0008270; GO:0042178; GO:0042802; GO:0051289; GO:0070062; GO:0070402 8515 XM_029356583.2 530 127 203 458 638 NA NA NA NA NA NA 8516 XM_029333082.2 192 156 167 115 447 NA NA NA NA NA NA 8517 XM_044306894.1 8 0 17 0 11 Q5SY80 2.52e-32 Cation channel sperm-associated auxiliary subunit epsilon (CatSper-epsilon) (CatSperepsilon) Homo sapiens (Human) flagellated sperm motility [GO:0030317]; sperm capacitation [GO:0048240] GO:0030317; GO:0036128; GO:0048240; GO:0097228 8518 XM_029329451.2 2974 4998 2916 3267 7795 NA NA NA NA NA NA 8519 XM_029340741.2 84 5 40 51 93 P48442 1.2e-125 Extracellular calcium-sensing receptor (CaSR) (Parathyroid cell calcium-sensing receptor) (PCaR1) (RaKCaR) Rattus norvegicus (Rat) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; apoptotic process [GO:0006915]; bile acid secretion [GO:0032782]; branching morphogenesis of an epithelial tube [GO:0048754]; calcium ion import [GO:0070509]; cellular calcium ion homeostasis [GO:0006874]; cellular response to glucose stimulus [GO:0071333]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hypoxia [GO:0071456]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to peptide [GO:1901653]; cellular response to vitamin D [GO:0071305]; chloride transmembrane transport [GO:1902476]; detection of calcium ion [GO:0005513]; fat pad development [GO:0060613]; G protein-coupled receptor signaling pathway [GO:0007186]; JNK cascade [GO:0007254]; ossification [GO:0001503]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of ATP-dependent activity [GO:0032781]; positive regulation of calcium ion import [GO:0090280]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin secretion [GO:0032024]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of vasoconstriction [GO:0045907]; regulation of calcium ion transport [GO:0051924]; response to calcium ion [GO:0051592]; response to fibroblast growth factor [GO:0071774]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to organic cyclic compound [GO:0014070]; vasodilation [GO:0042311] GO:0001503; GO:0002931; GO:0004930; GO:0005178; GO:0005509; GO:0005513; GO:0005634; GO:0005737; GO:0005886; GO:0006874; GO:0006915; GO:0007186; GO:0007193; GO:0007200; GO:0007254; GO:0008284; GO:0009986; GO:0010038; GO:0010628; GO:0014070; GO:0016020; GO:0016323; GO:0016324; GO:0016597; GO:0019901; GO:0030424; GO:0032024; GO:0032781; GO:0032782; GO:0035729; GO:0042311; GO:0042803; GO:0043005; GO:0043025; GO:0043679; GO:0044325; GO:0045907; GO:0048754; GO:0050927; GO:0051592; GO:0051924; GO:0060613; GO:0070374; GO:0070509; GO:0071305; GO:0071333; GO:0071404; GO:0071456; GO:0071774; GO:0090280; GO:1901653; GO:1902476 8520 XM_029357455.2 5500 3201 2351 4431 3253 Q6F754 2.04e-96 Glycine betaine transporter Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) nitrogen compound transport [GO:0071705] GO:0005886; GO:0022857; GO:0071705 8521 XM_044317824.1 1570 893 509 1478 1246 Q14184 5.69e-95 Double C2-like domain-containing protein beta (Doc2-beta) Homo sapiens (Human) calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-dependent activation of synaptic vesicle fusion [GO:0099502]; exocytosis [GO:0006887]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of insulin secretion [GO:0032024]; positive regulation of vesicle fusion [GO:0031340]; protein localization [GO:0008104]; regulation of calcium ion-dependent exocytosis [GO:0017158]; spontaneous neurotransmitter secretion [GO:0061669] GO:0005509; GO:0005544; GO:0005737; GO:0005886; GO:0006887; GO:0008104; GO:0017158; GO:0019905; GO:0031340; GO:0032024; GO:0045202; GO:0045956; GO:0048791; GO:0061669; GO:0098793; GO:0099502 8522 XM_029350595.2 373 189 339 423 931 NA NA NA NA NA NA 8523 XM_029343846.2 54 82 91 130 90 P11046 4.46e-112 Laminin subunit beta-1 (Laminin B1 chain) Drosophila melanogaster (Fruit fly) animal organ development [GO:0048513]; animal organ morphogenesis [GO:0009887]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cardiac muscle cell development [GO:0055013]; cell adhesion mediated by integrin [GO:0033627]; cell migration [GO:0016477]; defense response to Gram-negative bacterium [GO:0050829]; embryonic heart tube morphogenesis [GO:0003143]; extracellular matrix organization [GO:0030198]; gonad development [GO:0008406]; imaginal disc-derived wing morphogenesis [GO:0007476]; positive regulation of innate immune response [GO:0045089]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888] GO:0003143; GO:0005576; GO:0005604; GO:0005925; GO:0007476; GO:0008406; GO:0009887; GO:0009888; GO:0016477; GO:0030198; GO:0033627; GO:0034446; GO:0043256; GO:0045089; GO:0048513; GO:0050829; GO:0055013; GO:0062023; GO:0070831; GO:0071711 8524 XM_029343846.2 54 82 91 130 90 P11046 3.26e-32 Laminin subunit beta-1 (Laminin B1 chain) Drosophila melanogaster (Fruit fly) animal organ development [GO:0048513]; animal organ morphogenesis [GO:0009887]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cardiac muscle cell development [GO:0055013]; cell adhesion mediated by integrin [GO:0033627]; cell migration [GO:0016477]; defense response to Gram-negative bacterium [GO:0050829]; embryonic heart tube morphogenesis [GO:0003143]; extracellular matrix organization [GO:0030198]; gonad development [GO:0008406]; imaginal disc-derived wing morphogenesis [GO:0007476]; positive regulation of innate immune response [GO:0045089]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888] GO:0003143; GO:0005576; GO:0005604; GO:0005925; GO:0007476; GO:0008406; GO:0009887; GO:0009888; GO:0016477; GO:0030198; GO:0033627; GO:0034446; GO:0043256; GO:0045089; GO:0048513; GO:0050829; GO:0055013; GO:0062023; GO:0070831; GO:0071711 8525 XM_029343846.2 54 82 91 130 90 P11046 2.37e-29 Laminin subunit beta-1 (Laminin B1 chain) Drosophila melanogaster (Fruit fly) animal organ development [GO:0048513]; animal organ morphogenesis [GO:0009887]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cardiac muscle cell development [GO:0055013]; cell adhesion mediated by integrin [GO:0033627]; cell migration [GO:0016477]; defense response to Gram-negative bacterium [GO:0050829]; embryonic heart tube morphogenesis [GO:0003143]; extracellular matrix organization [GO:0030198]; gonad development [GO:0008406]; imaginal disc-derived wing morphogenesis [GO:0007476]; positive regulation of innate immune response [GO:0045089]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888] GO:0003143; GO:0005576; GO:0005604; GO:0005925; GO:0007476; GO:0008406; GO:0009887; GO:0009888; GO:0016477; GO:0030198; GO:0033627; GO:0034446; GO:0043256; GO:0045089; GO:0048513; GO:0050829; GO:0055013; GO:0062023; GO:0070831; GO:0071711 8526 XM_044312310.1 20 0 0 423 25 P43141 1.05e-31 Beta-4C adrenergic receptor (Beta-4C adrenoreceptor) (Beta-4C adrenoceptor) Meleagris gallopavo (Wild turkey) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; positive regulation of heart contraction [GO:0045823] GO:0004940; GO:0005886; GO:0007189; GO:0045823 8527 XM_044319659.1 11 0 31 6 61 NA NA NA NA NA NA 8528 XM_044323259.1 15 0 0 7 28 NA NA NA NA NA NA 8529 XM_044318945.1 17 7 5 8 18 Q0P4Y8 2.75e-71 Lipase maturation factor 2 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) protein maturation [GO:0051604] GO:0005789; GO:0051604 8530 XM_044318945.1 17 7 5 8 18 Q0P4Y8 8.39e-45 Lipase maturation factor 2 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) protein maturation [GO:0051604] GO:0005789; GO:0051604 8531 XM_029355609.2 0 24 9 7 15 NA NA NA NA NA NA 8532 XM_029354874.2 0 0 6 0 9 NA NA NA NA NA NA 8533 XM_029339715.2 96 107 11 177 207 Q3TXU5 3.12e-175 Deoxyhypusine synthase (DHS) (EC 2.5.1.46) Mus musculus (Mouse) glucose homeostasis [GO:0042593]; peptidyl-lysine modification to peptidyl-hypusine [GO:0008612]; positive regulation of T cell proliferation [GO:0042102]; spermidine catabolic process [GO:0046203]; spermidine metabolic process [GO:0008216] GO:0005737; GO:0008216; GO:0008612; GO:0034038; GO:0042102; GO:0042593; GO:0042802; GO:0046203 8534 XM_029357430.2 2191 1288 735 669 788 A7MBF6 1.73e-148 Armadillo-like helical domain containing protein 1 Bos taurus (Bovine) NA NA 8535 XM_044326753.1 19 0 2 0 0 Q9UTA8 3.12e-24 Uncharacterized methyltransferase-like C25B8.10 (EC 2.1.1.-) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) cellular detoxification [GO:1990748]; methylation [GO:0032259] GO:0005634; GO:0005829; GO:0008168; GO:0032259; GO:0046547; GO:1990748 8536 XM_029328930.2 111 0 48 16 110 Q8BLA8 4.35e-126 Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Wasabi receptor) Mus musculus (Mouse) calcium ion transmembrane import into cytosol [GO:0097553]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cell surface receptor signaling pathway [GO:0007166]; cellular calcium ion homeostasis [GO:0006874]; cellular response to carbon dioxide [GO:0071244]; cellular response to cold [GO:0070417]; cellular response to heat [GO:0034605]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to organic substance [GO:0071310]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; positive regulation of anion transport [GO:1903793]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of sensory perception of pain [GO:1904058]; protein homotetramerization [GO:0051289]; regulation of blood circulation [GO:1903522]; regulation of neuronal action potential [GO:0098908]; response to cold [GO:0009409]; response to hydrogen peroxide [GO:0042542]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; sensory perception of pain [GO:0019233]; thermoception [GO:0050955]; urinary bladder smooth muscle contraction [GO:0014832] GO:0005216; GO:0005245; GO:0005262; GO:0005886; GO:0006816; GO:0006874; GO:0007166; GO:0009409; GO:0009410; GO:0010033; GO:0014070; GO:0014832; GO:0015267; GO:0015278; GO:0016020; GO:0016324; GO:0019233; GO:0030424; GO:0032421; GO:0034605; GO:0035774; GO:0042542; GO:0042802; GO:0048265; GO:0050955; GO:0050966; GO:0050968; GO:0050974; GO:0051289; GO:0070301; GO:0070417; GO:0070588; GO:0071244; GO:0071310; GO:0097553; GO:0097604; GO:0098908; GO:1903522; GO:1903793; GO:1904058; GO:1990760 8537 XM_044320817.1 0 2 6 1 0 NA NA NA NA NA NA 8538 XM_029351487.2 0 0 0 0 80 Q5TZA2 1.18e-66 Rootletin (Ciliary rootlet coiled-coil protein) Homo sapiens (Human) cellular homeostasis [GO:0019725]; centriole-centriole cohesion [GO:0010457]; centrosome cycle [GO:0007098]; ciliary basal body organization [GO:0032053]; epithelial structure maintenance [GO:0010669]; establishment of localization in cell [GO:0051649]; establishment of organelle localization [GO:0051656]; photoreceptor cell maintenance [GO:0045494]; positive regulation of cilium assembly [GO:0045724]; positive regulation of protein localization to cilium [GO:1903566]; protein localization [GO:0008104]; protein localization to organelle [GO:0033365] GO:0001917; GO:0003779; GO:0005198; GO:0005200; GO:0005813; GO:0005814; GO:0005829; GO:0005886; GO:0007098; GO:0008104; GO:0010457; GO:0010669; GO:0015629; GO:0019725; GO:0019894; GO:0032053; GO:0033365; GO:0035253; GO:0045494; GO:0045724; GO:0051649; GO:0051656; GO:0070062; GO:0097729; GO:0120219; GO:1903566 8539 XM_029344987.2 65 42 67 21 228 Q9EQD2 4.34e-23 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 8540 XR_006394075.1 122 0 0 61 0 NA NA NA NA NA NA 8541 XM_029342665.2 1306 457 718 1426 859 Q58A42 6.41e-89 Protein DD3-3 Dictyostelium discoideum (Social amoeba) NA GO:0016020 8542 XM_044325388.1 1241 1247 1031 1568 1022 Q9CYF5 6.98e-83 RCC1-like G exchanging factor-like protein (RCC1-like) (Williams-Beuren syndrome chromosomal region 16 protein homolog) Mus musculus (Mouse) mitochondrial fusion [GO:0008053]; positive regulation of mitochondrial translation [GO:0070131] GO:0005085; GO:0005739; GO:0005743; GO:0008053; GO:0019843; GO:0031966; GO:0070131 8543 XM_044310895.1 0 0 69 16 20 NA NA NA NA NA NA 8544 XM_029344275.2 407 194 235 188 304 NA NA NA NA NA NA 8545 XM_044312357.1 1 0 0 219 349 Q3B7T1 0 Erythroid differentiation-related factor 1 Homo sapiens (Human) positive regulation of DNA-templated transcription [GO:0045893] GO:0005634; GO:0045893 8546 XM_029355128.2 753 972 510 651 706 Q7SYE0 8.56e-69 Autophagy-related protein 13 Danio rerio (Zebrafish) (Brachydanio rerio) mitophagy [GO:0000423]; piecemeal microautophagy of the nucleus [GO:0034727]; protein localization to phagophore assembly site [GO:0034497] GO:0000407; GO:0000423; GO:0005829; GO:0019898; GO:0034497; GO:0034727; GO:1990316 8547 XM_029347059.2 260 124 158 0 33 P42893 3.93e-169 Endothelin-converting enzyme 1 (ECE-1) (EC 3.4.24.71) Rattus norvegicus (Rat) apoptotic process [GO:0006915]; axonogenesis involved in innervation [GO:0060385]; blood vessel diameter maintenance [GO:0097746]; bradykinin catabolic process [GO:0010815]; calcitonin catabolic process [GO:0010816]; ear development [GO:0043583]; embryonic digit morphogenesis [GO:0042733]; embryonic heart tube development [GO:0035050]; endothelin maturation [GO:0034959]; gene expression [GO:0010467]; heart development [GO:0007507]; hormone catabolic process [GO:0042447]; neuron projection development [GO:0031175]; peptide hormone processing [GO:0016486]; pharyngeal system development [GO:0060037]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of receptor recycling [GO:0001921]; protein processing [GO:0016485]; regulation of blood pressure [GO:0008217]; regulation of ERK1 and ERK2 cascade [GO:0070372]; response to cadmium ion [GO:0046686]; response to hypoxia [GO:0001666]; response to muscle stretch [GO:0035994]; response to xenobiotic stimulus [GO:0009410]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; substance P catabolic process [GO:0010814]; sympathetic neuron axon guidance [GO:0097492] GO:0001666; GO:0001921; GO:0004175; GO:0004222; GO:0005768; GO:0005769; GO:0005886; GO:0006915; GO:0007507; GO:0008217; GO:0008270; GO:0009410; GO:0009897; GO:0010467; GO:0010613; GO:0010814; GO:0010815; GO:0010816; GO:0016020; GO:0016485; GO:0016486; GO:0030141; GO:0031175; GO:0031410; GO:0031982; GO:0033093; GO:0034959; GO:0035050; GO:0035994; GO:0042447; GO:0042733; GO:0042802; GO:0042803; GO:0043583; GO:0043950; GO:0045745; GO:0046686; GO:0048471; GO:0060037; GO:0060385; GO:0070372; GO:0097492; GO:0097746; GO:1902287 8548 XR_006395285.1 6 8 17 0 31 NA NA NA NA NA NA 8549 XM_029340380.2 100 134 55 70 76 NA NA NA NA NA NA 8550 XM_029333628.2 4303 4026 2961 4248 3635 Q9BDJ3 2.77e-24 Thioredoxin (Trx) Callithrix jacchus (White-tufted-ear marmoset) positive regulation of DNA binding [GO:0043388]; response to radiation [GO:0009314] GO:0005576; GO:0005634; GO:0005737; GO:0009314; GO:0015035; GO:0043388 8551 XR_006397953.1 0 0 0 0 20 Q9BX70 5.1e-54 BTB/POZ domain-containing protein 2 Homo sapiens (Human) neurogenesis [GO:0022008] GO:0000932; GO:0005829; GO:0022008 8552 XR_006393740.1 4 0 7 0 8 NA NA NA NA NA NA 8553 XM_029355819.2 3 38 26 27 28 NA NA NA NA NA NA 8554 XM_044319823.1 168 116 1024 101 2704 NA NA NA NA NA NA 8555 XM_029338858.2 543 2096 290 1597 475 Q5RD26 4.27e-66 Heterogeneous nuclear ribonucleoprotein H2 (hnRNP H2) (Heterogeneous nuclear ribonucleoprotein H') (hnRNP H') [Cleaved into: Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed] Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003723; GO:0005654; GO:1990904 8556 XM_044326396.1 99 92 218 281 225 NA NA NA NA NA NA 8557 XM_044327969.1 228 65 90 111 218 NA NA NA NA NA NA 8558 XM_044319657.1 7 0 9 16 41 NA NA NA NA NA NA 8559 XM_044314036.1 27 0 23 36 13 NA NA NA NA NA NA 8560 XM_029332667.2 3384 2360 2758 4555 4213 NA NA NA NA NA NA 8561 XM_029337581.2 1129 249 325 1990 975 B6ZLK2 0 Chromodomain-helicase-DNA-binding protein 1 (CHD-1) (EC 3.6.4.12) (ATP-dependent helicase CHD1) Gallus gallus (Chicken) chromatin remodeling [GO:0006338]; nucleosome organization [GO:0034728]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000775; GO:0000785; GO:0003677; GO:0003682; GO:0004386; GO:0005524; GO:0005634; GO:0006338; GO:0006357; GO:0016887; GO:0034728; GO:0042393; GO:0140658 8562 XM_029337581.2 1129 249 325 1990 975 B6ZLK2 1.65e-27 Chromodomain-helicase-DNA-binding protein 1 (CHD-1) (EC 3.6.4.12) (ATP-dependent helicase CHD1) Gallus gallus (Chicken) chromatin remodeling [GO:0006338]; nucleosome organization [GO:0034728]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000775; GO:0000785; GO:0003677; GO:0003682; GO:0004386; GO:0005524; GO:0005634; GO:0006338; GO:0006357; GO:0016887; GO:0034728; GO:0042393; GO:0140658 8563 XM_029334493.2 912 826 448 722 244 NA NA NA NA NA NA 8564 XM_044325424.1 25 22 16 0 0 NA NA NA NA NA NA 8565 XM_029328992.2 518 443 1662 25229 2355 NA NA NA NA NA NA 8566 XR_006395172.1 65 0 18 18 22 NA NA NA NA NA NA 8567 XR_003827641.2 14 0 0 29 0 NA NA NA NA NA NA 8568 XM_029336551.2 726 516 501 566 724 Q9DCJ5 1.13e-36 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (Complex I-19kD) (CI-19kD) (Complex I-PGIV) (CI-PGIV) (NADH-ubiquinone oxidoreductase 19 kDa subunit) Mus musculus (Mouse) aerobic respiration [GO:0009060]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrial respiratory chain complex I assembly [GO:0032981]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776] GO:0005739; GO:0005743; GO:0005747; GO:0005758; GO:0006120; GO:0009060; GO:0032981; GO:0042776; GO:0044877 8569 XM_029334529.2 160 494 29 42 0 E1C1L6 1.15e-104 Ectonucleoside triphosphate diphosphohydrolase 5 (NTPDase 5) (EC 3.6.1.6) (Guanosine-diphosphatase ENTPD5) (GDPase ENTPD5) (Uridine-diphosphatase ENTPD5) (UDPase ENTPD5) Gallus gallus (Chicken) 'de novo' post-translational protein folding [GO:0051084]; nucleoside diphosphate catabolic process [GO:0009134]; protein N-linked glycosylation [GO:0006487]; UDP catabolic process [GO:0006256]; UDP-glucose metabolic process [GO:0006011] GO:0004382; GO:0005576; GO:0005783; GO:0006011; GO:0006256; GO:0006487; GO:0009134; GO:0016020; GO:0017110; GO:0036384; GO:0043262; GO:0045134; GO:0051084; GO:1990003 8570 XM_029338800.2 9 0 36 46 57 B3EWZ7 5.3e-102 Threonine-rich protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 8571 XM_044315502.1 77 78 28 70 39 NA NA NA NA NA NA 8572 XM_044311932.1 232 113 113 327 356 NA NA NA NA NA NA 8573 XM_029357713.2 2298 1203 805 1271 1349 Q9CXV1 3.18e-36 Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial (CybS) (CII-4) (QPs3) (Succinate dehydrogenase complex subunit D) (Succinate-ubiquinone oxidoreductase cytochrome b small subunit) (Succinate-ubiquinone reductase membrane anchor subunit) Mus musculus (Mouse) cellular response to hypoxia [GO:0071456]; mitochondrial electron transport, succinate to ubiquinone [GO:0006121]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776]; regulation of catecholamine secretion [GO:0050433]; tricarboxylic acid cycle [GO:0006099] GO:0005739; GO:0005743; GO:0005749; GO:0006099; GO:0006121; GO:0008177; GO:0020037; GO:0042776; GO:0045257; GO:0046872; GO:0048039; GO:0050433; GO:0071456 8574 XM_029333125.2 273 426 388 1148 1056 Q9HAR2 4.38e-85 Adhesion G protein-coupled receptor L3 (Calcium-independent alpha-latrotoxin receptor 3) (CIRL-3) (Latrophilin-3) (Lectomedin-3) Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; brain development [GO:0007420]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; G protein-coupled receptor signaling pathway [GO:0007186]; neuron migration [GO:0001764]; synapse assembly [GO:0007416] GO:0001764; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007166; GO:0007186; GO:0007189; GO:0007416; GO:0007420; GO:0016020; GO:0030246; GO:0030424; GO:0098742; GO:0098978 8575 XM_044311528.1 487 117 189 508 405 Q7RTR2 4.55e-26 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 8576 XM_044311528.1 487 117 189 508 405 Q7RTR2 1.32e-25 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 8577 XM_044311528.1 487 117 189 508 405 Q7RTR2 1.81e-24 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 8578 XM_044311528.1 487 117 189 508 405 Q7RTR2 2.2e-23 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 8579 XM_044311528.1 487 117 189 508 405 Q7RTR2 5.21e-23 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 8580 XM_029356968.2 2531 2144 749 1924 995 Q7LL04 3.05e-31 UPF0676 protein C1494.01 Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) NA GO:0005634; GO:0005829 8581 XM_044324758.1 247 220 151 504 356 O88871 0 Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51) Rattus norvegicus (Rat) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; gamma-aminobutyric acid signaling pathway [GO:0007214]; neuron-glial cell signaling [GO:0150099]; synaptic transmission, GABAergic [GO:0051932] GO:0004888; GO:0004965; GO:0005737; GO:0005886; GO:0007193; GO:0007214; GO:0016020; GO:0030425; GO:0038039; GO:0042734; GO:0043005; GO:0043204; GO:0045211; GO:0046982; GO:0051932; GO:0098978; GO:0098982; GO:0150099; GO:1902710; GO:1902712 8582 XM_029356414.2 5 2 3 6 5 NA NA NA NA NA NA 8583 XM_029333917.2 2614 1931 1685 6580 3855 Q8IWB9 8.52e-37 Testis-expressed protein 2 (Transmembrane protein 96) Homo sapiens (Human) lipid transport [GO:0006869]; signal transduction [GO:0007165]; sphingolipid metabolic process [GO:0006665] GO:0005783; GO:0005789; GO:0006665; GO:0006869; GO:0007165; GO:0008289; GO:0016020; GO:0031965 8584 XM_029333917.2 2614 1931 1685 6580 3855 Q8IWB9 2.93e-21 Testis-expressed protein 2 (Transmembrane protein 96) Homo sapiens (Human) lipid transport [GO:0006869]; signal transduction [GO:0007165]; sphingolipid metabolic process [GO:0006665] GO:0005783; GO:0005789; GO:0006665; GO:0006869; GO:0007165; GO:0008289; GO:0016020; GO:0031965 8585 XM_044323527.1 5 4 8 0 53 NA NA NA NA NA NA 8586 XM_029350692.2 79 59 93 70 139 Q08DF7 3.92e-137 2',5'-phosphodiesterase 12 (2'-PDE) (2-PDE) (EC 3.1.4.-) (Mitochondrial deadenylase) (EC 3.1.13.4) Bos taurus (Bovine) cellular response to dsRNA [GO:0071359]; cellular response to interferon-alpha [GO:0035457]; cellular response to type II interferon [GO:0071346]; mitochondrial mRNA catabolic process [GO:0000958]; mRNA processing [GO:0006397]; negative regulation of cell death [GO:0060548]; negative regulation of oxidative phosphorylation [GO:0090324]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; positive regulation of viral genome replication [GO:0045070]; regulation of mitochondrial mRNA stability [GO:0044528] GO:0000175; GO:0000288; GO:0000958; GO:0004527; GO:0004535; GO:0005739; GO:0005759; GO:0006397; GO:0035457; GO:0044528; GO:0045070; GO:0046872; GO:0060548; GO:0071346; GO:0071359; GO:0090324 8587 XR_006393411.1 5 0 7 0 0 NA NA NA NA NA NA 8588 XR_006392944.1 41 2 25 5 151 NA NA NA NA NA NA 8589 XM_044327882.1 49 12 23 36 9 P08953 4.08e-65 Protein toll Drosophila melanogaster (Fruit fly) antifungal innate immune response [GO:0061760]; cell adhesion [GO:0007155]; cell competition in a multicellular organism [GO:0035212]; defense response to Gram-positive bacterium [GO:0050830]; defense response to oomycetes [GO:0002229]; detection of virus [GO:0009597]; dorsal/ventral axis specification [GO:0009950]; heart development [GO:0007507]; innate immune response [GO:0045087]; larval somatic muscle development [GO:0007526]; negative regulation of cell growth [GO:0030308]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of multicellular organism growth [GO:0040015]; positive regulation of antifungal peptide production [GO:0002804]; positive regulation of antimicrobial peptide production [GO:0002225]; positive regulation of hemocyte proliferation [GO:0035208]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of embryonic pattern specification [GO:1902875]; response to tumor cell [GO:0002347]; response to wounding [GO:0009611]; synapse assembly [GO:0007416]; synaptic target inhibition [GO:0016201]; Toll signaling pathway [GO:0008063]; toll-like receptor signaling pathway [GO:0002224] GO:0002224; GO:0002225; GO:0002229; GO:0002347; GO:0002804; GO:0004888; GO:0004896; GO:0005769; GO:0005886; GO:0007155; GO:0007416; GO:0007507; GO:0007526; GO:0008063; GO:0009597; GO:0009611; GO:0009897; GO:0009950; GO:0009986; GO:0016201; GO:0019955; GO:0030308; GO:0032154; GO:0035208; GO:0035212; GO:0038023; GO:0040015; GO:0042802; GO:0045087; GO:0045944; GO:0046627; GO:0046790; GO:0050135; GO:0050830; GO:0061760; GO:0061809; GO:0070976; GO:1902875 8590 XM_029351177.2 20 11 26 107 81 NA NA NA NA NA NA 8591 XR_006396251.1 13 7 4 5 44 P22897 1.57e-104 Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0001618; GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 8592 XR_006396251.1 13 7 4 5 44 P22897 1.57e-104 Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0001618; GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 8593 XR_006396251.1 13 7 4 5 44 P22897 1.72e-88 Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0001618; GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 8594 XR_006396251.1 13 7 4 5 44 P22897 1.72e-88 Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0001618; GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 8595 XR_006396251.1 13 7 4 5 44 P22897 2.17e-85 Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0001618; GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 8596 XR_006396251.1 13 7 4 5 44 P22897 3.36e-73 Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0001618; GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 8597 XR_006396251.1 13 7 4 5 44 P22897 2.05e-54 Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0001618; GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 8598 XR_006396251.1 13 7 4 5 44 P22897 2.05e-54 Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0001618; GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 8599 XR_006396251.1 13 7 4 5 44 P22897 4.08e-52 Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0001618; GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 8600 XM_044313320.1 22 26 8 30 30 NA NA NA NA NA NA 8601 XR_003825514.2 0 0 22 11 14 NA NA NA NA NA NA 8602 XM_044319593.1 18 23 2 6 23 NA NA NA NA NA NA 8603 XM_044316508.1 0 0 13 3 19 NA NA NA NA NA NA 8604 XM_029346216.2 327 90 37 54 488 NA NA NA NA NA NA 8605 XM_044316142.1 5 3 0 4 26 NA NA NA NA NA NA 8606 XM_029343015.2 2790 2493 1910 3172 2972 Q2KIH7 0 Phenylalanine-4-hydroxylase (PAH) (EC 1.14.16.1) (Phe-4-monooxygenase) Bos taurus (Bovine) L-phenylalanine catabolic process [GO:0006559]; tyrosine biosynthetic process [GO:0006571] GO:0004505; GO:0005506; GO:0006559; GO:0006571 8607 XM_044311278.1 58 36 38 67 47 NA NA NA NA NA NA 8608 XM_029332115.2 20 20 0 20 27 NA NA NA NA NA NA 8609 XM_044317739.1 103 2 10 24 469 Q69ZM6 5.67e-159 Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog) Mus musculus (Mouse) axoneme assembly [GO:0035082]; brain development [GO:0007420]; cilium assembly [GO:0060271]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; positive regulation of hh target transcription factor activity [GO:0007228]; positive regulation of smoothened signaling pathway [GO:0045880]; post-embryonic development [GO:0009791]; protein phosphorylation [GO:0006468]; regulation of DNA-binding transcription factor activity [GO:0051090]; smoothened signaling pathway [GO:0007224] GO:0001222; GO:0003351; GO:0004674; GO:0005524; GO:0005576; GO:0005634; GO:0005737; GO:0005829; GO:0005856; GO:0006468; GO:0007224; GO:0007228; GO:0007420; GO:0009791; GO:0035082; GO:0042995; GO:0045880; GO:0046872; GO:0051090; GO:0060271; GO:0106310 8610 XM_044308247.1 349 426 318 282 673 Q8CGZ0 1.92e-31 Calcium homeostasis endoplasmic reticulum protein (SR-related CTD-associated factor 6) Mus musculus (Mouse) cellular calcium ion homeostasis [GO:0006874]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; release of sequestered calcium ion into cytosol [GO:0051209]; RNA processing [GO:0006396] GO:0003723; GO:0005737; GO:0006396; GO:0006874; GO:0008285; GO:0033017; GO:0044325; GO:0048471; GO:0051209; GO:0070886 8611 XM_044317469.1 153 150 476 197 84 Q60HG2 5.27e-87 Torsin-1A (Dystonia 1 protein) (Torsin ATPase 1) (EC 3.6.4.-) (Torsin family 1 member A) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) cell adhesion [GO:0007155]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated protein folding [GO:0061077]; ER-associated misfolded protein catabolic process [GO:0071712]; intermediate filament cytoskeleton organization [GO:0045104]; neuron projection development [GO:0031175]; nuclear envelope organization [GO:0006998]; nuclear membrane organization [GO:0071763]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; protein deneddylation [GO:0000338]; protein localization to nucleus [GO:0034504]; regulation of dopamine uptake involved in synaptic transmission [GO:0051584]; regulation of protein localization to cell surface [GO:2000008]; synaptic vesicle membrane organization [GO:0048499]; synaptic vesicle transport [GO:0048489]; wound healing, spreading of cells [GO:0044319] GO:0000338; GO:0005524; GO:0005635; GO:0005788; GO:0005856; GO:0006998; GO:0007155; GO:0008021; GO:0016887; GO:0030141; GO:0030426; GO:0030659; GO:0031175; GO:0031965; GO:0034504; GO:0042406; GO:0042802; GO:0044319; GO:0045104; GO:0048489; GO:0048499; GO:0051085; GO:0051584; GO:0061077; GO:0071712; GO:0071763; GO:0140662; GO:1900244; GO:2000008 8612 XM_044319422.1 62 45 34 22 67 Q28CX0 1.39e-26 Elongator complex protein 6 (Protein TMEM103) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) positive regulation of cell migration [GO:0030335]; tRNA wobble uridine modification [GO:0002098] GO:0002098; GO:0030335; GO:0033588 8613 XM_029348848.2 1834 2042 1660 1256 1565 Q15024 5.39e-108 Exosome complex component RRP42 (Exosome component 7) (Ribosomal RNA-processing protein 42) (p8) Homo sapiens (Human) exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear mRNA surveillance [GO:0071028]; nuclear polyadenylation-dependent mRNA catabolic process [GO:0071042]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; U1 snRNA 3'-end processing [GO:0034473]; U4 snRNA 3'-end processing [GO:0034475]; U5 snRNA 3'-end processing [GO:0034476] GO:0000175; GO:0000176; GO:0000177; GO:0000178; GO:0000467; GO:0003723; GO:0005634; GO:0005654; GO:0005730; GO:0005829; GO:0006364; GO:0006396; GO:0006401; GO:0016075; GO:0034427; GO:0034473; GO:0034475; GO:0034476; GO:0043928; GO:0071028; GO:0071035; GO:0071038; GO:0071042; GO:0101019 8614 XM_029351150.2 9 97 39 19 145 Q80T21 4.37e-117 ADAMTS-like protein 4 (ADAMTSL-4) (Thrombospondin repeat-containing protein 1) Mus musculus (Mouse) apoptotic process [GO:0006915]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; pigment cell development [GO:0070285]; positive regulation of apoptotic process [GO:0043065] GO:0002020; GO:0002064; GO:0005576; GO:0005614; GO:0006915; GO:0030198; GO:0031012; GO:0042802; GO:0043065; GO:0070285 8615 XM_029349721.2 948 1460 893 3283 2243 A0A8I3PDQ1 3.07e-29 Enhancer of filamentation 1 (CRK-associated substrate-related protein) (CAS-L) (Neural precursor cell expressed developmentally down-regulated protein 9) (NEDD-9) (p105) Canis lupus familiaris (Dog) (Canis familiaris) activation of GTPase activity [GO:0090630]; cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell division [GO:0051301]; cilium disassembly [GO:0061523]; learning or memory [GO:0007611]; lymphocyte migration into lymphoid organs [GO:0097021]; negative regulation of cell migration [GO:0030336]; positive regulation of dendritic spine maintenance [GO:1902952]; positive regulation of immunological synapse formation [GO:2000522]; positive regulation of lymphocyte chemotaxis [GO:0140131]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of protein localization [GO:1903829]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of actin cytoskeleton organization [GO:0032956] GO:0000922; GO:0001772; GO:0005654; GO:0005794; GO:0005829; GO:0005925; GO:0005938; GO:0007049; GO:0007155; GO:0007611; GO:0016323; GO:0030027; GO:0030336; GO:0032956; GO:0036064; GO:0045672; GO:0051301; GO:0061098; GO:0061523; GO:0072686; GO:0090630; GO:0097021; GO:0140131; GO:1900026; GO:1902952; GO:1903829; GO:1990782; GO:2000522 8616 XM_029351451.2 213 177 261 158 226 NA NA NA NA NA NA 8617 XM_044311788.1 49 3 123 10 214 NA NA NA NA NA NA 8618 XM_044313413.1 18 0 19 1 30 Q09575 1.08e-33 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 8619 XM_029348708.2 2700 2585 2642 3030 2223 Q9FIC3 1.32e-23 Protein BOLA2 Arabidopsis thaliana (Mouse-ear cress) cellular iron ion homeostasis [GO:0006879]; protein maturation by iron-sulfur cluster transfer [GO:0097428]; response to iron ion [GO:0010039]; response to oxidative stress [GO:0006979] GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0006879; GO:0006979; GO:0010039; GO:0051536; GO:0051537; GO:0097428 8620 XM_044321565.1 1019 822 302 676 409 O35114 1.86e-86 Lysosome membrane protein 2 (85 kDa lysosomal membrane sialoglycoprotein) (LGP85) (Lysosome membrane protein II) (LIMP II) (Scavenger receptor class B member 2) Mus musculus (Mouse) aminophospholipid transport [GO:0015917]; gene expression [GO:0010467]; positive regulation of neuron projection development [GO:0010976]; protein targeting to lysosome [GO:0006622]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular carbohydrate catabolic process [GO:0043471]; regulation of glucosylceramidase activity [GO:1905123]; sensory perception of sound [GO:0007605] GO:0001786; GO:0005044; GO:0005737; GO:0005765; GO:0005886; GO:0006622; GO:0006898; GO:0007605; GO:0010467; GO:0010976; GO:0015485; GO:0015917; GO:0019899; GO:0030666; GO:0031210; GO:0038024; GO:0042803; GO:0043202; GO:0043471; GO:0051087; GO:1905123 8621 XR_003827577.2 0 8 0 4 0 NA NA NA NA NA NA 8622 XM_029336958.2 430 393 196 222 170 A2RT91 5.71e-82 Ankyrin and armadillo repeat-containing protein Mus musculus (Mouse) NA GO:0016020 8623 XM_029344735.2 1225 922 506 1342 858 Q8BIQ5 1.65e-88 Cleavage stimulation factor subunit 2 (CF-1 64 kDa subunit) (Cleavage stimulation factor 64 kDa subunit) (CSTF 64 kDa subunit) (CstF-64) Mus musculus (Mouse) cellular response to nerve growth factor stimulus [GO:1990090]; pre-mRNA cleavage required for polyadenylation [GO:0098789] GO:0003723; GO:0003729; GO:0005654; GO:0005847; GO:0016604; GO:0071920; GO:0098789; GO:1990090 8624 XM_044318058.1 301 261 113 132 406 NA NA NA NA NA NA 8625 XR_006396528.1 469 213 270 323 241 NA NA NA NA NA NA 8626 XM_029323537.2 478 371 274 427 326 O05218 1.83e-93 Glutathione hydrolase-like YwrD proenzyme (EC 2.3.2.2) (Putative gamma-glutamyltransferase YwrD) (EC 3.4.19.13) [Cleaved into: Glutathione hydrolase-like YwrD large chain; Glutathione hydrolase-like YwrD small chain] Bacillus subtilis (strain 168) glutathione catabolic process [GO:0006751]; proteolysis [GO:0006508] GO:0006508; GO:0006751; GO:0036374; GO:0102953; GO:0103068 8627 XM_029350834.2 295 262 223 225 255 O55029 0 Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP) (p102) Mus musculus (Mouse) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; toxin transport [GO:1901998] GO:0000139; GO:0005080; GO:0005198; GO:0005794; GO:0005829; GO:0006886; GO:0006888; GO:0006890; GO:0006891; GO:0030126; GO:1901998 8628 XM_029355866.2 194 116 95 150 245 NA NA NA NA NA NA 8629 XM_044322702.1 32 15 48 78 31 Q7Q5R7 6.62e-78 Choline transporter-like 1 Anopheles gambiae (African malaria mosquito) transmembrane transport [GO:0055085] GO:0016020; GO:0022857; GO:0055085 8630 XM_044308651.1 1086 1068 890 1326 1268 Q5XHZ0 0 Heat shock protein 75 kDa, mitochondrial (HSP 75) (TNFR-associated protein 1) (Tumor necrosis factor type 1 receptor-associated protein) (TRAP-1) Rattus norvegicus (Rat) negative regulation of cellular respiration [GO:1901856]; negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide [GO:1903751]; protein folding [GO:0006457]; translational attenuation [GO:0009386] GO:0003723; GO:0005524; GO:0005654; GO:0005743; GO:0005758; GO:0005759; GO:0006457; GO:0009386; GO:0016887; GO:0019901; GO:0051082; GO:0071944; GO:0140662; GO:1901856; GO:1903751 8631 XM_044310932.1 2182 2454 0 27 1909 NA NA NA NA NA NA 8632 XM_029351720.2 26 59 15 75 19 NA NA NA NA NA NA 8633 XM_044324606.1 377 51 207 57 327 Q17LW0 5.6e-96 Myosin-VIIa (Protein crinkled) Aedes aegypti (Yellowfever mosquito) (Culex aegypti) actin filament-based movement [GO:0030048]; antennal morphogenesis [GO:0048800]; chaeta morphogenesis [GO:0008407]; imaginal disc-derived wing hair organization [GO:0035317]; sensory perception of sound [GO:0007605] GO:0000146; GO:0003779; GO:0005524; GO:0005737; GO:0007605; GO:0008407; GO:0016459; GO:0030048; GO:0032027; GO:0035317; GO:0048800; GO:0071944; GO:0120025 8634 XM_044324606.1 377 51 207 57 327 Q17LW0 6.52e-25 Myosin-VIIa (Protein crinkled) Aedes aegypti (Yellowfever mosquito) (Culex aegypti) actin filament-based movement [GO:0030048]; antennal morphogenesis [GO:0048800]; chaeta morphogenesis [GO:0008407]; imaginal disc-derived wing hair organization [GO:0035317]; sensory perception of sound [GO:0007605] GO:0000146; GO:0003779; GO:0005524; GO:0005737; GO:0007605; GO:0008407; GO:0016459; GO:0030048; GO:0032027; GO:0035317; GO:0048800; GO:0071944; GO:0120025 8635 XR_003823717.2 138 63 78 19 88 NA NA NA NA NA NA 8636 XM_044308446.1 0 14 5 16 0 Q02357 2.83e-67 Ankyrin-1 (ANK-1) (Erythrocyte ankyrin) Mus musculus (Mouse) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; erythrocyte development [GO:0048821]; inorganic cation transmembrane transport [GO:0098662]; iron ion homeostasis [GO:0055072]; porphyrin-containing compound biosynthetic process [GO:0006779]; positive regulation of organelle organization [GO:0010638]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005634; GO:0005886; GO:0006779; GO:0006888; GO:0007165; GO:0008093; GO:0009898; GO:0010638; GO:0014731; GO:0016020; GO:0016529; GO:0019899; GO:0019903; GO:0030018; GO:0030507; GO:0030673; GO:0030863; GO:0031430; GO:0031672; GO:0042383; GO:0043005; GO:0044325; GO:0045211; GO:0048821; GO:0051117; GO:0055072; GO:0072659; GO:0098662 8637 XM_044308446.1 0 14 5 16 0 Q02357 3.41e-59 Ankyrin-1 (ANK-1) (Erythrocyte ankyrin) Mus musculus (Mouse) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; erythrocyte development [GO:0048821]; inorganic cation transmembrane transport [GO:0098662]; iron ion homeostasis [GO:0055072]; porphyrin-containing compound biosynthetic process [GO:0006779]; positive regulation of organelle organization [GO:0010638]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005634; GO:0005886; GO:0006779; GO:0006888; GO:0007165; GO:0008093; GO:0009898; GO:0010638; GO:0014731; GO:0016020; GO:0016529; GO:0019899; GO:0019903; GO:0030018; GO:0030507; GO:0030673; GO:0030863; GO:0031430; GO:0031672; GO:0042383; GO:0043005; GO:0044325; GO:0045211; GO:0048821; GO:0051117; GO:0055072; GO:0072659; GO:0098662 8638 XM_044308446.1 0 14 5 16 0 Q02357 2.24e-46 Ankyrin-1 (ANK-1) (Erythrocyte ankyrin) Mus musculus (Mouse) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; erythrocyte development [GO:0048821]; inorganic cation transmembrane transport [GO:0098662]; iron ion homeostasis [GO:0055072]; porphyrin-containing compound biosynthetic process [GO:0006779]; positive regulation of organelle organization [GO:0010638]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005634; GO:0005886; GO:0006779; GO:0006888; GO:0007165; GO:0008093; GO:0009898; GO:0010638; GO:0014731; GO:0016020; GO:0016529; GO:0019899; GO:0019903; GO:0030018; GO:0030507; GO:0030673; GO:0030863; GO:0031430; GO:0031672; GO:0042383; GO:0043005; GO:0044325; GO:0045211; GO:0048821; GO:0051117; GO:0055072; GO:0072659; GO:0098662 8639 XM_044308446.1 0 14 5 16 0 Q02357 1.12e-44 Ankyrin-1 (ANK-1) (Erythrocyte ankyrin) Mus musculus (Mouse) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; erythrocyte development [GO:0048821]; inorganic cation transmembrane transport [GO:0098662]; iron ion homeostasis [GO:0055072]; porphyrin-containing compound biosynthetic process [GO:0006779]; positive regulation of organelle organization [GO:0010638]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005634; GO:0005886; GO:0006779; GO:0006888; GO:0007165; GO:0008093; GO:0009898; GO:0010638; GO:0014731; GO:0016020; GO:0016529; GO:0019899; GO:0019903; GO:0030018; GO:0030507; GO:0030673; GO:0030863; GO:0031430; GO:0031672; GO:0042383; GO:0043005; GO:0044325; GO:0045211; GO:0048821; GO:0051117; GO:0055072; GO:0072659; GO:0098662 8640 XM_044308446.1 0 14 5 16 0 Q02357 5.88e-23 Ankyrin-1 (ANK-1) (Erythrocyte ankyrin) Mus musculus (Mouse) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; erythrocyte development [GO:0048821]; inorganic cation transmembrane transport [GO:0098662]; iron ion homeostasis [GO:0055072]; porphyrin-containing compound biosynthetic process [GO:0006779]; positive regulation of organelle organization [GO:0010638]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005634; GO:0005886; GO:0006779; GO:0006888; GO:0007165; GO:0008093; GO:0009898; GO:0010638; GO:0014731; GO:0016020; GO:0016529; GO:0019899; GO:0019903; GO:0030018; GO:0030507; GO:0030673; GO:0030863; GO:0031430; GO:0031672; GO:0042383; GO:0043005; GO:0044325; GO:0045211; GO:0048821; GO:0051117; GO:0055072; GO:0072659; GO:0098662 8641 XM_029330346.2 55 80 149 22 66 NA NA NA NA NA NA 8642 XR_006391595.1 0 0 23 0 174 NA NA NA NA NA NA 8643 XR_003826252.2 15 7 7 26 9 F6QEU4 4.58e-33 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 8644 XR_003826252.2 15 7 7 26 9 F6QEU4 4.58e-33 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 8645 XM_029356883.2 659 409 339 499 380 P52569 3.12e-167 Cationic amino acid transporter 2 (CAT-2) (CAT2) (Low affinity cationic amino acid transporter 2) (Solute carrier family 7 member 2) Homo sapiens (Human) amino acid import across plasma membrane [GO:0089718]; amino acid transport [GO:0006865]; L-alpha-amino acid transmembrane transport [GO:1902475]; L-amino acid transport [GO:0015807]; L-arginine import across plasma membrane [GO:0097638]; L-arginine transmembrane transport [GO:1903826]; L-ornithine transmembrane transport [GO:1903352]; transport across blood-brain barrier [GO:0150104] GO:0000064; GO:0005886; GO:0006865; GO:0015171; GO:0015174; GO:0015179; GO:0015189; GO:0015807; GO:0030054; GO:0061459; GO:0089718; GO:0097638; GO:0150104; GO:1902475; GO:1903352; GO:1903826 8646 XM_044312611.1 3 0 6 14 6 NA NA NA NA NA NA 8647 XM_029356835.2 1043 800 27 930 39 NA NA NA NA NA NA 8648 XM_044320548.1 16 21 10 6 3 NA NA NA NA NA NA 8649 XM_029335799.2 24 21 7 36 11 P29147 1.36e-56 D-beta-hydroxybutyrate dehydrogenase, mitochondrial (EC 1.1.1.30) (3-hydroxybutyrate dehydrogenase) (BDH) Rattus norvegicus (Rat) adipose tissue development [GO:0060612]; brain development [GO:0007420]; liver development [GO:0001889]; response to cadmium ion [GO:0046686]; response to corticosterone [GO:0051412]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to growth hormone [GO:0060416]; response to hormone [GO:0009725]; response to insulin [GO:0032868]; response to nutrient [GO:0007584]; response to starvation [GO:0042594]; response to toxic substance [GO:0009636]; response to xenobiotic stimulus [GO:0009410]; steroid metabolic process [GO:0008202] GO:0001889; GO:0003858; GO:0005543; GO:0005743; GO:0005759; GO:0007420; GO:0007584; GO:0008202; GO:0009410; GO:0009636; GO:0009725; GO:0016491; GO:0032355; GO:0032868; GO:0042594; GO:0043231; GO:0045471; GO:0046686; GO:0051412; GO:0060416; GO:0060612; GO:0099617 8650 XM_029356041.2 10 4 0 3 14 NA NA NA NA NA NA 8651 XM_044328655.1 130 81 42 76 44 Q92820 9.96e-87 Gamma-glutamyl hydrolase (EC 3.4.19.9) (Conjugase) (GH) (Gamma-Glu-X carboxypeptidase) Homo sapiens (Human) tetrahydrofolylpolyglutamate metabolic process [GO:0046900] GO:0005576; GO:0005615; GO:0005634; GO:0005773; GO:0008238; GO:0008242; GO:0034722; GO:0035578; GO:0035580; GO:0042470; GO:0046900; GO:0070062; GO:1904724 8652 XM_044328612.1 191 139 75 172 221 O43299 1.32e-84 AP-5 complex subunit zeta-1 (Adaptor-related protein complex 5 zeta subunit) (Zeta5) Homo sapiens (Human) double-strand break repair via homologous recombination [GO:0000724]; endosomal transport [GO:0016197]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] GO:0000724; GO:0005634; GO:0005654; GO:0005737; GO:0005770; GO:0015031; GO:0016192; GO:0016197; GO:0016607; GO:0030119; GO:0044599 8653 XR_006397824.1 49 15 57 20 25 NA NA NA NA NA NA 8654 XM_029329229.2 169 20 0 89 38 Q9UI40 9.93e-60 Sodium/potassium/calcium exchanger 2 (Na(+)/K(+)/Ca(2+)-exchange protein 2) (Retinal cone Na-Ca+K exchanger) (Solute carrier family 24 member 2) Homo sapiens (Human) calcium ion import [GO:0070509]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; cellular response to high light intensity [GO:0071486]; cone photoresponse recovery [GO:0036368]; establishment of localization in cell [GO:0051649]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; learning [GO:0007612]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; neuron cellular homeostasis [GO:0070050]; phototransduction [GO:0007602]; potassium ion transmembrane transport [GO:0071805]; sodium ion transmembrane transport [GO:0035725] GO:0001917; GO:0005262; GO:0005886; GO:0006811; GO:0006874; GO:0007602; GO:0007612; GO:0007613; GO:0008273; GO:0015293; GO:0034220; GO:0035725; GO:0036368; GO:0051649; GO:0060291; GO:0060292; GO:0070050; GO:0070509; GO:0070588; GO:0071486; GO:0071805; GO:0098703 8655 XM_044323766.1 151 0 28 0 0 NA NA NA NA NA NA 8656 XM_044324765.1 1537 823 334 714 625 Q96RW7 8.69e-53 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 8657 XM_044324765.1 1537 823 334 714 625 Q96RW7 4.54e-43 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 8658 XM_044324765.1 1537 823 334 714 625 Q96RW7 8.01e-43 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 8659 XM_044324765.1 1537 823 334 714 625 Q96RW7 8.22e-38 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 8660 XM_044324765.1 1537 823 334 714 625 Q96RW7 9.1e-38 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 8661 XM_044324765.1 1537 823 334 714 625 Q96RW7 2.19e-35 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 8662 XM_044324765.1 1537 823 334 714 625 Q96RW7 9.87e-34 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 8663 XM_044324765.1 1537 823 334 714 625 Q96RW7 4.44e-33 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 8664 XM_044324765.1 1537 823 334 714 625 Q96RW7 4.05e-32 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 8665 XM_044324765.1 1537 823 334 714 625 Q96RW7 7.64e-30 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 8666 XM_044324765.1 1537 823 334 714 625 Q96RW7 1.25e-27 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 8667 XM_044324765.1 1537 823 334 714 625 Q96RW7 4.75e-26 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 8668 XM_029357927.2 40 0 24 4 85 Q1L8X9 6.75e-84 Vesicular glutamate transporter 3 (VGluT3) (Solute carrier family 17 member 8) Danio rerio (Zebrafish) (Brachydanio rerio) anion transport [GO:0006820]; equilibrioception [GO:0050957]; L-glutamate import [GO:0051938]; L-glutamate transmembrane transport [GO:0015813]; neurotransmitter loading into synaptic vesicle [GO:0098700]; phosphate ion homeostasis [GO:0055062]; positive regulation of glutamate uptake involved in transmission of nerve impulse [GO:0051951]; regulation of acetylcholine uptake [GO:0051631]; regulation of synapse structure or activity [GO:0050803]; sodium-dependent phosphate transport [GO:0044341]; synaptic transmission, glutamatergic [GO:0035249]; vestibular reflex [GO:0060005] GO:0005254; GO:0005313; GO:0005326; GO:0005436; GO:0005886; GO:0006820; GO:0015813; GO:0016020; GO:0022857; GO:0030672; GO:0034707; GO:0035249; GO:0043005; GO:0044341; GO:0050803; GO:0050957; GO:0051631; GO:0051938; GO:0051951; GO:0055062; GO:0060005; GO:0060076; GO:0098700; GO:0140788 8669 XM_029357927.2 40 0 24 4 85 Q1L8X9 6.75e-84 Vesicular glutamate transporter 3 (VGluT3) (Solute carrier family 17 member 8) Danio rerio (Zebrafish) (Brachydanio rerio) anion transport [GO:0006820]; equilibrioception [GO:0050957]; L-glutamate import [GO:0051938]; L-glutamate transmembrane transport [GO:0015813]; neurotransmitter loading into synaptic vesicle [GO:0098700]; phosphate ion homeostasis [GO:0055062]; positive regulation of glutamate uptake involved in transmission of nerve impulse [GO:0051951]; regulation of acetylcholine uptake [GO:0051631]; regulation of synapse structure or activity [GO:0050803]; sodium-dependent phosphate transport [GO:0044341]; synaptic transmission, glutamatergic [GO:0035249]; vestibular reflex [GO:0060005] GO:0005254; GO:0005313; GO:0005326; GO:0005436; GO:0005886; GO:0006820; GO:0015813; GO:0016020; GO:0022857; GO:0030672; GO:0034707; GO:0035249; GO:0043005; GO:0044341; GO:0050803; GO:0050957; GO:0051631; GO:0051938; GO:0051951; GO:0055062; GO:0060005; GO:0060076; GO:0098700; GO:0140788 8670 XM_029342677.2 35 8 0 9 0 Q8TDX7 3.19e-175 Serine/threonine-protein kinase Nek7 (EC 2.7.11.1) (Never in mitosis A-related kinase 7) (NimA-related protein kinase 7) Homo sapiens (Human) cellular response to potassium ion [GO:0035865]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of NLRP3 inflammasome complex assembly [GO:1900227]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein phosphorylation [GO:0006468]; regulation of mitotic cell cycle [GO:0007346]; spindle assembly [GO:0051225] GO:0000922; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005815; GO:0005874; GO:0006468; GO:0007346; GO:0018105; GO:0032212; GO:0035865; GO:0046872; GO:0051225; GO:0051973; GO:0106310; GO:0140677; GO:1900227; GO:1904355 8671 XM_044322802.1 0 0 201 0 0 Q13591 1.51e-71 Semaphorin-5A (Semaphorin-F) (Sema F) Homo sapiens (Human) axon extension [GO:0048675]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell-cell signaling [GO:0007267]; diencephalon development [GO:0021536]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of cell adhesion [GO:0007162]; negative regulation of endothelial cell apoptotic process [GO:2000352]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; positive chemotaxis [GO:0050918]; positive regulation of actin filament depolymerization [GO:0030836]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein kinase B signaling [GO:0051897]; semaphorin-plexin signaling pathway [GO:0071526]; signal clustering [GO:1990256] GO:0001755; GO:0001938; GO:0002043; GO:0005886; GO:0007155; GO:0007162; GO:0007267; GO:0007399; GO:0007411; GO:0007413; GO:0016020; GO:0021536; GO:0030215; GO:0030335; GO:0030836; GO:0035373; GO:0043395; GO:0045499; GO:0045545; GO:0045766; GO:0048675; GO:0048842; GO:0048843; GO:0050918; GO:0051897; GO:0060326; GO:0070062; GO:0071526; GO:0090263; GO:1990256; GO:2000352; GO:2001028 8672 XM_029341479.2 1505 1773 1258 2175 2627 A0PJE2 1.07e-129 Dehydrogenase/reductase SDR family member 12 (EC 1.1.-.-) (Short-chain dehydrogenase/reductase family 40C member 1) (Protein SDR40C1) Homo sapiens (Human) NA GO:0016491 8673 XM_044318833.1 77 54 87 22 180 NA NA NA NA NA NA 8674 XM_029329525.2 365 420 227 322 302 Q49LS8 8.64e-47 XK-related protein 6 Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon nigroviridis) NA GO:0005886 8675 XM_044315148.1 39 18 24 0 7 NA NA NA NA NA NA 8676 XM_044310826.1 3 14 0 0 7 Q58L91 7e-25 Venom prothrombin activator oscutarin-C non-catalytic subunit (vPA) (Venom coagulation factor Va-like protein) [Cleaved into: Oscutarin-C non-catalytic subunit heavy chain; Oscutarin-C non-catalytic subunit light chain] Oxyuranus scutellatus (Coastal taipan) envenomation resulting in positive regulation of blood coagulation in another organism [GO:0044469]; positive regulation of blood coagulation in another organism [GO:0035807]; positive regulation of peptidase activity [GO:0010952] GO:0005507; GO:0005576; GO:0010952; GO:0016504; GO:0032991; GO:0035807; GO:0044469; GO:0090729 8677 XM_029335122.2 0 25 0 0 0 Q20191 1.39e-43 Zinc metalloproteinase nas-13 (EC 3.4.24.-) (Nematode astacin 13) Caenorhabditis elegans proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0006508; GO:0008270 8678 XM_029326505.2 20 4 12 6 6 NA NA NA NA NA NA 8679 XM_044310945.1 28 2 8 173 27 NA NA NA NA NA NA 8680 XM_029333828.2 3 4 3 0 19 NA NA NA NA NA NA 8681 XR_006393495.1 33 19 4 13 51 NA NA NA NA NA NA 8682 XM_029334211.2 145 137 154 116 213 NA NA NA NA NA NA 8683 XM_029341302.2 164 79 92 107 143 Q8VCX6 4.97e-101 KICSTOR complex protein kaptin Mus musculus (Mouse) actin filament organization [GO:0007015]; cellular response to amino acid starvation [GO:0034198]; cellular response to glucose starvation [GO:0042149]; negative regulation of TORC1 signaling [GO:1904262]; protein localization to lysosome [GO:0061462] GO:0005765; GO:0007015; GO:0030027; GO:0031941; GO:0032420; GO:0034198; GO:0042149; GO:0051015; GO:0061462; GO:0098871; GO:0140007; GO:1904262 8684 XR_006393732.1 3 11 0 3 0 NA NA NA NA NA NA 8685 XM_029347964.2 887 913 416 1063 366 NA NA NA NA NA NA 8686 XM_029331000.2 46 54 36 34 50 Q8VZP1 2.09e-72 (DL)-glycerol-3-phosphatase 2 (EC 3.1.3.21) (Glycerol-1-phosphatase 2) (Haloacid dehalogenase-like hydrolase domain-containing protein GPP2) Arabidopsis thaliana (Mouse-ear cress) dephosphorylation [GO:0016311]; glycerol biosynthetic process [GO:0006114] GO:0000121; GO:0005739; GO:0005829; GO:0006114; GO:0016311; GO:0016791; GO:0043136; GO:0046872; GO:0050308 8687 XM_029356998.2 3688 3389 4047 4274 3174 C3ZWH9 1.92e-35 CDGSH iron-sulfur domain-containing protein 2 homolog A Branchiostoma floridae (Florida lancelet) (Amphioxus) regulation of autophagy [GO:0010506] GO:0005741; GO:0005789; GO:0010506; GO:0046872; GO:0051537 8688 XM_044314135.1 1 11 66 45 38 NA NA NA NA NA NA 8689 XM_044313860.1 393 453 328 555 801 NA NA NA NA NA NA 8690 XM_029332735.2 700 162 191 231 143 NA NA NA NA NA NA 8691 XM_044328185.1 6378 10436 4757 6242 3908 Q9CPY6 2.15e-100 Glucose-induced degradation protein 4 homolog (Vacuolar import and degradation protein 24 homolog) Mus musculus (Mouse) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] GO:0000151; GO:0043161; GO:0061630 8692 XR_006392053.1 1 0 12 24 20 NA NA NA NA NA NA 8693 XM_029330167.2 360 517 344 452 466 Q80XH1 2.23e-23 KxDL motif-containing protein 1 Mus musculus (Mouse) lysosome localization [GO:0032418]; organelle transport along microtubule [GO:0072384]; regulation of endosome size [GO:0051036]; regulation of lysosome size [GO:0062196]; vesicle-mediated transport [GO:0016192] GO:0016192; GO:0032418; GO:0051036; GO:0062196; GO:0072384; GO:0098574; GO:0099078 8694 XM_044326202.1 26 0 1 37 11 NA NA NA NA NA NA 8695 XM_029341026.2 333 316 321 432 360 Q9NXG6 2.38e-46 Transmembrane prolyl 4-hydroxylase (P4H-TM) (EC 1.14.11.29) (Hypoxia-inducible factor prolyl hydroxylase 4) (HIF-PH4) (HIF-prolyl hydroxylase 4) (HPH-4) Homo sapiens (Human) peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; regulation of erythrocyte differentiation [GO:0045646] GO:0004656; GO:0005506; GO:0005509; GO:0005783; GO:0005789; GO:0016706; GO:0018401; GO:0031418; GO:0045646 8696 XM_044324588.1 313 68 49 2 35 NA NA NA NA NA NA 8697 XM_029340967.2 0 0 0 68 27 Q52KW8 1.94e-145 Protein RCC2 homolog Xenopus laevis (African clawed frog) cell cycle [GO:0007049]; cell division [GO:0051301] GO:0000775; GO:0005730; GO:0005737; GO:0005819; GO:0005886; GO:0007049; GO:0030496; GO:0051301 8698 XM_029344636.2 52 56 10 23 15 NA NA NA NA NA NA 8699 XR_003825212.2 0 0 0 0 20 NA NA NA NA NA NA 8700 XM_029343600.2 542 383 323 637 748 Q3T094 2.21e-92 Persulfide dioxygenase ETHE1, mitochondrial (EC 1.13.11.18) (Sulfur dioxygenase ETHE1) Bos taurus (Bovine) glutathione metabolic process [GO:0006749]; hydrogen sulfide metabolic process [GO:0070813] GO:0005506; GO:0005654; GO:0005739; GO:0005759; GO:0006749; GO:0042802; GO:0050313; GO:0070813 8701 XM_044316372.1 8 0 0 1 0 NA NA NA NA NA NA 8702 XM_029342075.2 4248 2232 4407 2753 3890 Q5VXJ0 7.76e-102 Lipase member K (EC 3.1.1.-) (Lipase-like abhydrolase domain-containing protein 2) Homo sapiens (Human) cornification [GO:0070268]; lipid catabolic process [GO:0016042] GO:0004465; GO:0005576; GO:0016042; GO:0043231; GO:0070268 8703 XM_029344682.2 228 300 301 106 247 Q9CYL5 1.97e-24 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Mus musculus (Mouse) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070374 8704 XM_044306822.1 27 33 31 29 0 NA NA NA NA NA NA 8705 XM_029353053.2 0 0 0 6 7 P84239 1.5e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 8706 XM_044317383.1 1092 27 313 3 346 NA NA NA NA NA NA 8707 XM_029347324.2 483 248 335 307 516 Q4R381 0 Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.356) (Enhancer of zeste homolog 2) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) chromatin remodeling [GO:0006338]; histone H3-K27 methylation [GO:0070734]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of retinoic acid receptor signaling pathway [GO:0048387]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511] GO:0000122; GO:0003682; GO:0006338; GO:0010718; GO:0035098; GO:0042752; GO:0043406; GO:0043547; GO:0045814; GO:0045892; GO:0046976; GO:0048387; GO:0048511; GO:0070734; GO:0071902; GO:0140951; GO:1990841 8708 XM_029327505.2 8 7 0 0 0 NA NA NA NA NA NA 8709 XR_006392376.1 0 6 4 1 1 NA NA NA NA NA NA 8710 XM_044316837.1 11 4 0 72 3 NA NA NA NA NA NA 8711 XM_029333339.2 408 581 600 895 424 NA NA NA NA NA NA 8712 XM_044324467.1 4 0 14 26 6 NA NA NA NA NA NA 8713 XM_029340966.2 180 108 111 181 138 Q52KW8 8.83e-146 Protein RCC2 homolog Xenopus laevis (African clawed frog) cell cycle [GO:0007049]; cell division [GO:0051301] GO:0000775; GO:0005730; GO:0005737; GO:0005819; GO:0005886; GO:0007049; GO:0030496; GO:0051301 8714 XR_006395539.1 193 61 88 126 151 NA NA NA NA NA NA 8715 XM_044309371.1 19 10 9 31 0 NA NA NA NA NA NA 8716 XR_006395191.1 37 10 25 9 66 NA NA NA NA NA NA 8717 XM_029356739.2 1022 744 671 908 1049 O75976 0 Carboxypeptidase D (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180) Homo sapiens (Human) peptide metabolic process [GO:0006518]; protein processing [GO:0016485] GO:0004181; GO:0004185; GO:0005615; GO:0005886; GO:0006518; GO:0008270; GO:0016020; GO:0016485; GO:0070062 8718 XM_029356739.2 1022 744 671 908 1049 O75976 0 Carboxypeptidase D (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180) Homo sapiens (Human) peptide metabolic process [GO:0006518]; protein processing [GO:0016485] GO:0004181; GO:0004185; GO:0005615; GO:0005886; GO:0006518; GO:0008270; GO:0016020; GO:0016485; GO:0070062 8719 XM_029356739.2 1022 744 671 908 1049 O75976 8.71e-178 Carboxypeptidase D (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180) Homo sapiens (Human) peptide metabolic process [GO:0006518]; protein processing [GO:0016485] GO:0004181; GO:0004185; GO:0005615; GO:0005886; GO:0006518; GO:0008270; GO:0016020; GO:0016485; GO:0070062 8720 XM_029356739.2 1022 744 671 908 1049 O75976 1.45e-51 Carboxypeptidase D (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180) Homo sapiens (Human) peptide metabolic process [GO:0006518]; protein processing [GO:0016485] GO:0004181; GO:0004185; GO:0005615; GO:0005886; GO:0006518; GO:0008270; GO:0016020; GO:0016485; GO:0070062 8721 XM_044321096.1 238 141 19 0 0 E9Q6P5 0 Tetratricopeptide repeat protein 7B (TPR repeat protein 7B) Mus musculus (Mouse) phosphatidylinositol phosphate biosynthetic process [GO:0046854]; protein localization to plasma membrane [GO:0072659] GO:0005829; GO:0005886; GO:0046854; GO:0072659 8722 XM_029336590.2 0 0 0 17 48 NA NA NA NA NA NA 8723 XM_044311891.1 0 163 98 244 32 NA NA NA NA NA NA 8724 XM_029329920.2 13 273 0 106 121 Q9BU79 2.24e-31 Transmembrane protein 243 (MDR1- and mitochondrial taxol resistance-associated protein) (MM-TRAG) Homo sapiens (Human) NA GO:0016020 8725 XM_044327395.1 21 0 0 0 1 NA NA NA NA NA NA 8726 XM_029350373.2 149 270 174 377 358 NA NA NA NA NA NA 8727 XM_029342835.2 17 0 75 0 0 P41777 6.69e-29 Nucleolar and coiled-body phosphoprotein 1 (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar 130 kDa protein) (Nucleolar phosphoprotein p130) Rattus norvegicus (Rat) axonogenesis [GO:0007409]; box H/ACA RNA metabolic process [GO:0033979]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; nucleolus organization [GO:0007000]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of protein import into nucleus [GO:0042306]; regulation of synaptic plasticity [GO:0048167]; regulation of translation [GO:0006417]; response to osmotic stress [GO:0006970] GO:0001093; GO:0001650; GO:0005524; GO:0005525; GO:0005654; GO:0005730; GO:0005737; GO:0006417; GO:0006970; GO:0007000; GO:0007409; GO:0008139; GO:0008284; GO:0014029; GO:0014032; GO:0015030; GO:0019904; GO:0030674; GO:0031428; GO:0031429; GO:0033979; GO:0034512; GO:0034513; GO:0042306; GO:0045893; GO:0046982; GO:0048167; GO:0062064; GO:0062065; GO:0140678 8728 XM_029341338.2 727 325 346 302 272 Q91WD2 1.54e-39 Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Calcium transport protein 1) (CaT1) (Epithelial calcium channel 2) (ECaC2) Mus musculus (Mouse) calcium ion homeostasis [GO:0055074]; calcium ion import [GO:0070509]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; parathyroid hormone secretion [GO:0035898]; protein homotetramerization [GO:0051289]; response to calcium ion [GO:0051592] GO:0005216; GO:0005262; GO:0005516; GO:0005886; GO:0006816; GO:0016020; GO:0034704; GO:0035898; GO:0042802; GO:0046872; GO:0051289; GO:0051592; GO:0055074; GO:0070509; GO:0070588; GO:0098703 8729 XM_029333286.2 86 62 8 23 38 P83858 2.57e-27 Pyroglutamylated RF-amide peptide receptor (AQ27) (G-protein coupled receptor 103) (Orexigenic neuropeptide QRFP receptor) (SP9155) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:0097730 8730 XM_029328406.2 0 158 0 14 22 Q0VFE3 9.68e-72 Post-GPI attachment to proteins factor 3 (PER1-like domain-containing protein 1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) GPI anchor biosynthetic process [GO:0006506]; GPI anchor metabolic process [GO:0006505] GO:0000139; GO:0005789; GO:0006505; GO:0006506; GO:0016788 8731 XM_029342096.2 795 591 510 614 620 Q8BGF9 8.19e-88 Solute carrier family 25 member 44 Mus musculus (Mouse) branched-chain amino acid catabolic process [GO:0009083]; branched-chain amino acid transport [GO:0015803]; regulation of cold-induced thermogenesis [GO:0120161] GO:0005739; GO:0005743; GO:0009083; GO:0015658; GO:0015803; GO:0120161 8732 XM_029331266.2 1587 1495 1103 1580 2022 P35738 4.46e-180 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial (EC 1.2.4.4) (Branched-chain alpha-keto acid dehydrogenase E1 component beta chain) (BCKDE1B) (BCKDH E1-beta) Rattus norvegicus (Rat) branched-chain amino acid catabolic process [GO:0009083]; lipid metabolic process [GO:0006629]; response to cAMP [GO:0051591]; response to glucocorticoid [GO:0051384]; response to nutrient [GO:0007584] GO:0003863; GO:0005654; GO:0005730; GO:0005739; GO:0005947; GO:0006629; GO:0007584; GO:0009083; GO:0044877; GO:0051384; GO:0051591 8733 XM_044310246.1 15 12 15 11 42 Q5F371 8.12e-53 Protein strawberry notch homolog 1 Gallus gallus (Chicken) regulation of DNA-templated transcription [GO:0006355]; regulation of response to stimulus [GO:0048583] GO:0005634; GO:0006355; GO:0031490; GO:0042393; GO:0048583 8734 XM_044310246.1 15 12 15 11 42 Q5F371 8.12e-53 Protein strawberry notch homolog 1 Gallus gallus (Chicken) regulation of DNA-templated transcription [GO:0006355]; regulation of response to stimulus [GO:0048583] GO:0005634; GO:0006355; GO:0031490; GO:0042393; GO:0048583 8735 XM_029358125.2 161 31 31 70 0 W6YKT9 4.51e-24 NA NA NA NA 8736 XR_003825500.2 111 197 21 87 22 NA NA NA NA NA NA 8737 XM_029333240.2 48 22 59 6 261 NA NA NA NA NA NA 8738 XR_006395526.1 117 11 166 127 93 NA NA NA NA NA NA 8739 XM_044324915.1 25 392 30 313 0 Q9JIS1 2.78e-63 Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2) Rattus norvegicus (Rat) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-ion regulated exocytosis [GO:0017156]; cell differentiation [GO:0030154]; establishment of localization in cell [GO:0051649]; exocytosis [GO:0006887]; insulin secretion [GO:0030073]; intracellular protein transport [GO:0006886]; maintenance of presynaptic active zone structure [GO:0048790]; neurotransmitter secretion [GO:0007269]; positive regulation of dendrite extension [GO:1903861]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of synaptic transmission [GO:0050806]; regulation of calcium-dependent activation of synaptic vesicle fusion [GO:0150037]; regulation of exocytosis [GO:0017157]; regulation of membrane potential [GO:0042391]; regulation of synaptic plasticity [GO:0048167]; spontaneous neurotransmitter secretion [GO:0061669]; synaptic vesicle docking [GO:0016081]; synaptic vesicle priming [GO:0016082] GO:0006886; GO:0006887; GO:0007188; GO:0007269; GO:0010628; GO:0016081; GO:0016082; GO:0017156; GO:0017157; GO:0019904; GO:0030073; GO:0030154; GO:0030674; GO:0031267; GO:0032991; GO:0042391; GO:0042734; GO:0042995; GO:0044325; GO:0044877; GO:0045202; GO:0046872; GO:0048167; GO:0048788; GO:0048790; GO:0048791; GO:0050806; GO:0051649; GO:0060077; GO:0061669; GO:0097151; GO:0098684; GO:0098831; GO:0098882; GO:0098978; GO:0098982; GO:0140677; GO:0150037; GO:1903861; GO:2000463 8740 XM_044324915.1 25 392 30 313 0 Q9JIS1 5.95e-31 Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2) Rattus norvegicus (Rat) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-ion regulated exocytosis [GO:0017156]; cell differentiation [GO:0030154]; establishment of localization in cell [GO:0051649]; exocytosis [GO:0006887]; insulin secretion [GO:0030073]; intracellular protein transport [GO:0006886]; maintenance of presynaptic active zone structure [GO:0048790]; neurotransmitter secretion [GO:0007269]; positive regulation of dendrite extension [GO:1903861]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of synaptic transmission [GO:0050806]; regulation of calcium-dependent activation of synaptic vesicle fusion [GO:0150037]; regulation of exocytosis [GO:0017157]; regulation of membrane potential [GO:0042391]; regulation of synaptic plasticity [GO:0048167]; spontaneous neurotransmitter secretion [GO:0061669]; synaptic vesicle docking [GO:0016081]; synaptic vesicle priming [GO:0016082] GO:0006886; GO:0006887; GO:0007188; GO:0007269; GO:0010628; GO:0016081; GO:0016082; GO:0017156; GO:0017157; GO:0019904; GO:0030073; GO:0030154; GO:0030674; GO:0031267; GO:0032991; GO:0042391; GO:0042734; GO:0042995; GO:0044325; GO:0044877; GO:0045202; GO:0046872; GO:0048167; GO:0048788; GO:0048790; GO:0048791; GO:0050806; GO:0051649; GO:0060077; GO:0061669; GO:0097151; GO:0098684; GO:0098831; GO:0098882; GO:0098978; GO:0098982; GO:0140677; GO:0150037; GO:1903861; GO:2000463 8741 XM_044324915.1 25 392 30 313 0 Q9JIS1 6.82e-25 Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2) Rattus norvegicus (Rat) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-ion regulated exocytosis [GO:0017156]; cell differentiation [GO:0030154]; establishment of localization in cell [GO:0051649]; exocytosis [GO:0006887]; insulin secretion [GO:0030073]; intracellular protein transport [GO:0006886]; maintenance of presynaptic active zone structure [GO:0048790]; neurotransmitter secretion [GO:0007269]; positive regulation of dendrite extension [GO:1903861]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of synaptic transmission [GO:0050806]; regulation of calcium-dependent activation of synaptic vesicle fusion [GO:0150037]; regulation of exocytosis [GO:0017157]; regulation of membrane potential [GO:0042391]; regulation of synaptic plasticity [GO:0048167]; spontaneous neurotransmitter secretion [GO:0061669]; synaptic vesicle docking [GO:0016081]; synaptic vesicle priming [GO:0016082] GO:0006886; GO:0006887; GO:0007188; GO:0007269; GO:0010628; GO:0016081; GO:0016082; GO:0017156; GO:0017157; GO:0019904; GO:0030073; GO:0030154; GO:0030674; GO:0031267; GO:0032991; GO:0042391; GO:0042734; GO:0042995; GO:0044325; GO:0044877; GO:0045202; GO:0046872; GO:0048167; GO:0048788; GO:0048790; GO:0048791; GO:0050806; GO:0051649; GO:0060077; GO:0061669; GO:0097151; GO:0098684; GO:0098831; GO:0098882; GO:0098978; GO:0098982; GO:0140677; GO:0150037; GO:1903861; GO:2000463 8742 XM_044325525.1 67 15 36 10 59 O15439 0 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 8743 XM_029346036.2 0 0 0 78 18 Q9NYG2 6.16e-40 Palmitoyltransferase ZDHHC3 (EC 2.3.1.225) (Acyltransferase ZDHHC3) (EC 2.3.1.-) (Protein DHHC1) (Zinc finger DHHC domain-containing protein 3) (DHHC-3) Homo sapiens (Human) lipoprotein localization to membrane [GO:0044873]; peptidyl-L-cysteine S-palmitoylation [GO:0018230]; positive regulation of receptor localization to synapse [GO:1902685]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; protein localization to photoreceptor outer segment [GO:1903546]; protein localization to plasma membrane [GO:0072659]; protein palmitoylation [GO:0018345]; protein targeting to membrane [GO:0006612]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; TRAIL-activated apoptotic signaling pathway [GO:0036462] GO:0000139; GO:0005783; GO:0005794; GO:0006612; GO:0008277; GO:0016020; GO:0016409; GO:0018230; GO:0018345; GO:0019705; GO:0019706; GO:0032230; GO:0036462; GO:0042803; GO:0044873; GO:0072659; GO:0140439; GO:1902685; GO:1903546 8744 XM_044328471.1 391 829 213 369 203 Q6DK98 1.23e-83 Nuclear distribution protein nudE-like 1-A Xenopus laevis (African clawed frog) lysosome localization [GO:0032418]; positive regulation of ruffle assembly [GO:1900029] GO:0005737; GO:0005815; GO:0005819; GO:0005874; GO:0008017; GO:0032418; GO:1900029 8745 XM_029356626.2 349 216 332 299 271 NA NA NA NA NA NA 8746 XM_029342619.2 198 103 312 191 152 P53603 0 Formimidoyltransferase-cyclodeaminase (Formiminotransferase-cyclodeaminase) (FTCD) [Includes: Glutamate formimidoyltransferase (EC 2.1.2.5) (Glutamate formiminotransferase) (Glutamate formyltransferase); Formimidoyltetrahydrofolate cyclodeaminase (EC 4.3.1.4) (Formiminotetrahydrofolate cyclodeaminase)] Sus scrofa (Pig) histidine catabolic process [GO:0006548]; histidine catabolic process to glutamate and formamide [GO:0019556]; histidine catabolic process to glutamate and formate [GO:0019557] GO:0005542; GO:0005794; GO:0005814; GO:0005829; GO:0006548; GO:0019556; GO:0019557; GO:0030409; GO:0030412 8747 XM_029348439.2 915 653 174 426 499 NA NA NA NA NA NA 8748 XM_044312658.1 15 159 10 52 33 NA NA NA NA NA NA 8749 XR_003823830.2 26 13 1272 8 8 NA NA NA NA NA NA 8750 XM_044309340.1 4 73 24 199 106 NA NA NA NA NA NA 8751 XM_029328070.2 4473 4691 2124 4385 4268 NA NA NA NA NA NA 8752 XM_044324058.1 93 187 83 273 253 NA NA NA NA NA NA 8753 XR_006396008.1 332 322 328 243 309 NA NA NA NA NA NA 8754 XR_006394922.1 0 6 0 0 26 NA NA NA NA NA NA 8755 XM_029341871.2 1066 497 496 645 564 Q3EBF7 9.88e-110 Delta(8)-fatty-acid desaturase 2 (EC 1.14.19.29) (Delta(8)-sphingolipid desaturase 2) (Sphingoid long-chain base desaturase 2) (Sphingoid LCB desaturase 2) (Sphingolipid 8-(E/Z)-desaturase 2) Arabidopsis thaliana (Mouse-ear cress) cellular response to cold [GO:0070417]; lipid metabolic process [GO:0006629]; sphingolipid biosynthetic process [GO:0030148] GO:0005783; GO:0005789; GO:0006629; GO:0016717; GO:0030148; GO:0046872; GO:0052631; GO:0070417 8756 XM_029339419.2 0 0 45 0 0 Q7T163 0 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 8757 XM_029339419.2 0 0 45 0 0 Q7T163 3.39e-42 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 8758 XM_029339419.2 0 0 45 0 0 Q7T163 3.28e-33 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 8759 XM_029339419.2 0 0 45 0 0 Q7T163 1.99e-29 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 8760 XM_029339419.2 0 0 45 0 0 Q7T163 5.14e-27 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 8761 XM_029339419.2 0 0 45 0 0 Q7T163 1.12e-22 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 8762 XR_006395720.1 18 0 0 34 42 Q9NYT0 1.02e-40 Pleckstrin-2 Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; intracellular signal transduction [GO:0035556]; positive regulation of plasma membrane bounded cell projection assembly [GO:0120034] GO:0005737; GO:0005856; GO:0005886; GO:0031258; GO:0031532; GO:0032266; GO:0035556; GO:0043325; GO:0080025; GO:0120034 8763 XM_029341999.2 938 697 360 528 350 Q9VE46 0 High-affinity choline transporter 1 Drosophila melanogaster (Fruit fly) acetylcholine biosynthetic process [GO:0008292]; amino acid transmembrane transport [GO:0003333]; choline transport [GO:0015871] GO:0003333; GO:0005307; GO:0005886; GO:0008292; GO:0015171; GO:0015220; GO:0015871; GO:0016020 8764 XM_044311249.1 0 0 0 0 9 NA NA NA NA NA NA 8765 XM_029328524.2 96 181 0 244 0 Q6GNG3 3.69e-85 Protein disulfide-isomerase TMX3 (EC 5.3.4.1) (Thioredoxin domain-containing protein 10) (Thioredoxin-related transmembrane protein 3) Xenopus laevis (African clawed frog) NA GO:0003756; GO:0005789 8766 XM_044307846.1 6 0 19 0 62 NA NA NA NA NA NA 8767 XM_044323149.1 26 8 6 16 33 Q5R5U3 1.08e-140 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 8768 XM_044323149.1 26 8 6 16 33 Q5R5U3 1.73e-138 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 8769 XM_044323149.1 26 8 6 16 33 Q5R5U3 1.62e-137 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 8770 XM_044323149.1 26 8 6 16 33 Q5R5U3 1.41e-136 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 8771 XM_044323149.1 26 8 6 16 33 Q5R5U3 4.53e-136 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 8772 XM_044323149.1 26 8 6 16 33 Q5R5U3 1.57e-125 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 8773 XM_044318891.1 56 41 0 0 0 NA NA NA NA NA NA 8774 XM_029328731.2 2052 1903 498 1542 1200 NA NA NA NA NA NA 8775 XM_044319531.1 0 0 7 0 0 NA NA NA NA NA NA 8776 XM_044309572.1 23 0 3 0 9 NA NA NA NA NA NA 8777 XM_029334986.2 497 708 124 771 352 A0JNI4 5.02e-100 Serine racemase (EC 4.3.1.17) (EC 4.3.1.18) (EC 5.1.1.18) (D-serine ammonia-lyase) (D-serine dehydratase) (L-serine ammonia-lyase) (L-serine dehydratase) Bos taurus (Bovine) D-serine biosynthetic process [GO:0070179]; D-serine metabolic process [GO:0070178]; L-serine metabolic process [GO:0006563]; pyruvate biosynthetic process [GO:0042866]; response to lipopolysaccharide [GO:0032496] GO:0000287; GO:0003941; GO:0005509; GO:0005524; GO:0005737; GO:0006563; GO:0008721; GO:0016594; GO:0018114; GO:0030165; GO:0030170; GO:0030378; GO:0032496; GO:0042803; GO:0042866; GO:0043025; GO:0070178; GO:0070179 8778 XM_029337798.2 12 16 4 65 136 Q9UA35 6.91e-152 Solute carrier family 28 member 3 (Concentrative Na(+)-nucleoside cotransporter 3) (hfCNT) Eptatretus stoutii (Pacific hagfish) NA GO:0005337; GO:0005886; GO:0015293 8779 XM_029330740.2 29 44 35 79 64 Q98T88 9.95e-27 Twisted gastrulation protein homolog 1-A Xenopus laevis (African clawed frog) NA GO:0005576 8780 XM_044311154.1 3 2 33 6 14 Q09575 3.65e-37 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 8781 XM_044307569.1 68 122 0 15 13 P22027 9.22e-31 ATP synthase subunit s, mitochondrial (ATP synthase-coupling factor B) (FB) (Distal membrane arm assembly complex 2-like protein) (Mitochondrial ATP synthase regulatory component factor B) Bos taurus (Bovine) ATP biosynthetic process [GO:0006754]; proton transmembrane transport [GO:1902600] GO:0005737; GO:0005743; GO:0006754; GO:0045263; GO:0046872; GO:1902600 8782 XM_029347822.2 1708 1326 985 2916 1620 Q14642 4.04e-117 Inositol polyphosphate-5-phosphatase A (EC 3.1.3.56) (43 kDa inositol polyphosphate 5-phosphatase) (Type I inositol 1,4,5-trisphosphate 5-phosphatase) (5PTase) Homo sapiens (Human) inositol phosphate dephosphorylation [GO:0046855]; inositol phosphate metabolic process [GO:0043647]; inositol phosphate-mediated signaling [GO:0048016]; negative regulation of neuron death [GO:1901215]; phosphatidylinositol dephosphorylation [GO:0046856] GO:0004445; GO:0005886; GO:0016020; GO:0030425; GO:0042731; GO:0043647; GO:0046855; GO:0046856; GO:0048016; GO:0052658; GO:0052659; GO:1901215 8783 XR_003824110.2 19993 10389 9387 17064 19696 NA NA NA NA NA NA 8784 XM_044315257.1 179 325 0 0 0 Q7RTR2 4.36e-53 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 8785 XM_044315257.1 179 325 0 0 0 Q7RTR2 1.2e-52 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 8786 XM_044315257.1 179 325 0 0 0 Q7RTR2 2.29e-44 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 8787 XM_029328642.2 2578 2871 2899 1891 2411 Q64414 5.14e-45 Adenine phosphoribosyltransferase (APRT) (EC 2.4.2.7) Dipodillus campestris (North African gerbil) (Gerbillus campestris) adenine salvage [GO:0006168]; AMP salvage [GO:0044209]; purine ribonucleoside salvage [GO:0006166] GO:0003999; GO:0005737; GO:0006166; GO:0006168; GO:0044209 8788 XM_029348440.2 2743 1555 802 1276 1191 NA NA NA NA NA NA 8789 XM_044318755.1 0 0 0 160 0 NA NA NA NA NA NA 8790 XM_044320859.1 17 30 20 39 61 NA NA NA NA NA NA 8791 XM_044310678.1 2209 1700 1397 1818 1582 Q01063 0 cAMP-specific 3',5'-cyclic phosphodiesterase 4D (EC 3.1.4.53) (DPDE3) Mus musculus (Mouse) adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; memory [GO:0007613]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil migration [GO:1990266]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of type II interferon production [GO:0032729]; protein-containing complex assembly [GO:0065003]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; signal transduction [GO:0007165]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852] GO:0001934; GO:0002027; GO:0004112; GO:0004114; GO:0004115; GO:0005634; GO:0005794; GO:0005813; GO:0005829; GO:0005886; GO:0005891; GO:0006198; GO:0006939; GO:0007165; GO:0007568; GO:0007613; GO:0008277; GO:0010469; GO:0010880; GO:0014911; GO:0016324; GO:0019899; GO:0022409; GO:0030016; GO:0030552; GO:0030593; GO:0031698; GO:0032729; GO:0032743; GO:0032754; GO:0032991; GO:0033137; GO:0034704; GO:0034705; GO:0035264; GO:0043949; GO:0043951; GO:0044325; GO:0045822; GO:0046872; GO:0048471; GO:0048661; GO:0050852; GO:0051117; GO:0060314; GO:0061028; GO:0065003; GO:0071222; GO:0071320; GO:0071872; GO:0071875; GO:0086004; GO:0097110; GO:1901363; GO:1901844; GO:1901898; GO:1990266 8792 XM_044319640.1 2 0 7 13 0 Q9CPW0 6.01e-40 Contactin-associated protein-like 2 (Cell recognition molecule Caspr2) Mus musculus (Mouse) action potential initiation [GO:0099610]; adult behavior [GO:0030534]; associative learning [GO:0008306]; axonogenesis [GO:0007409]; behavioral response to pain [GO:0048266]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell population proliferation [GO:0008283]; central nervous system myelination [GO:0022010]; cerebellar Purkinje cell layer morphogenesis [GO:0021692]; cerebellum development [GO:0021549]; chemical synaptic transmission [GO:0007268]; circadian sleep/wake cycle [GO:0042745]; clustering of voltage-gated potassium channels [GO:0045163]; dendrite arborization [GO:0140059]; dendritic spine development [GO:0060996]; dendritic spine maintenance [GO:0097062]; dendritic spine organization [GO:0097061]; embryonic brain development [GO:1990403]; ERK1 and ERK2 cascade [GO:0070371]; excitatory chemical synaptic transmission [GO:0098976]; excitatory postsynaptic potential [GO:0060079]; excitatory synapse assembly [GO:1904861]; fat cell differentiation [GO:0045444]; gene expression [GO:0010467]; glial cell proliferation [GO:0014009]; glutamatergic neuron differentiation [GO:1905962]; grooming behavior [GO:0007625]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; inhibitory chemical synaptic transmission [GO:0098977]; inhibitory synapse assembly [GO:1904862]; intracellular signal transduction [GO:0035556]; learning [GO:0007612]; limbic system development [GO:0021761]; locomotor rhythm [GO:0045475]; locomotory behavior [GO:0007626]; maintenance of synapse structure [GO:0099558]; mitochondrion organization [GO:0007005]; motor behavior [GO:0061744]; multicellular organism growth [GO:0035264]; myelination [GO:0042552]; negative regulation of neuronal action potential [GO:1904456]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; neural precursor cell proliferation [GO:0061351]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process [GO:0050905]; neuromuscular process controlling posture [GO:0050884]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuron recognition [GO:0008038]; neuronal action potential [GO:0019228]; positive regulation of gap junction assembly [GO:1903598]; positive regulation of neuronal action potential [GO:1904457]; postsynaptic density organization [GO:0097106]; protein kinase B signaling [GO:0043491]; protein localization [GO:0008104]; protein localization to juxtaparanode region of axon [GO:0071205]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; response to dietary excess [GO:0002021]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to interleukin-17 [GO:0097396]; response to light intensity [GO:0009642]; response to mechanical stimulus [GO:0009612]; response to metformin [GO:1901558]; response to odorant [GO:1990834]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; rhythmic behavior [GO:0007622]; social behavior [GO:0035176]; TOR signaling [GO:0031929]; transmission of nerve impulse [GO:0019226]; vocal learning [GO:0042297]; vocalization behavior [GO:0071625]; walking behavior [GO:0090659] GO:0000902; GO:0001701; GO:0002021; GO:0005769; GO:0005794; GO:0006954; GO:0007005; GO:0007155; GO:0007268; GO:0007409; GO:0007612; GO:0007622; GO:0007625; GO:0007626; GO:0008038; GO:0008076; GO:0008104; GO:0008283; GO:0008306; GO:0009408; GO:0009410; GO:0009612; GO:0009642; GO:0009725; GO:0009986; GO:0010033; GO:0010467; GO:0014009; GO:0016020; GO:0019226; GO:0019228; GO:0019899; GO:0021549; GO:0021692; GO:0021761; GO:0022010; GO:0030165; GO:0030424; GO:0030425; GO:0030534; GO:0030673; GO:0031175; GO:0031929; GO:0032229; GO:0033010; GO:0035176; GO:0035264; GO:0035556; GO:0042297; GO:0042552; GO:0042734; GO:0042745; GO:0043005; GO:0043025; GO:0043194; GO:0043491; GO:0044224; GO:0044309; GO:0044853; GO:0045163; GO:0045202; GO:0045444; GO:0045475; GO:0048265; GO:0048266; GO:0048787; GO:0048812; GO:0050884; GO:0050905; GO:0060076; GO:0060079; GO:0060996; GO:0061351; GO:0061744; GO:0070371; GO:0071205; GO:0071625; GO:0090659; GO:0097061; GO:0097062; GO:0097106; GO:0097396; GO:0098529; GO:0098793; GO:0098794; GO:0098976; GO:0098977; GO:0098978; GO:0098982; GO:0099072; GO:0099558; GO:0099610; GO:0140059; GO:0150048; GO:1901558; GO:1903598; GO:1904456; GO:1904457; GO:1904861; GO:1904862; GO:1905962; GO:1990403; GO:1990834 8793 XM_044316539.1 92 45 53 120 368 NA NA NA NA NA NA 8794 XM_029357574.2 3 1 29 23 19 B5X186 4.45e-67 Calumenin-A Salmo salar (Atlantic salmon) NA GO:0005509; GO:0005576; GO:0005789; GO:0005794; GO:0033018; GO:0042470 8795 XM_044320014.1 0 0 0 13 12 P35546 1.43e-54 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; anatomical structure morphogenesis [GO:0009653]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006919; GO:0007156; GO:0007158; GO:0007169; GO:0007399; GO:0009410; GO:0009653; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030182; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0098797; GO:2001241 8796 XM_044320014.1 0 0 0 13 12 P35546 1.43e-54 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; anatomical structure morphogenesis [GO:0009653]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006919; GO:0007156; GO:0007158; GO:0007169; GO:0007399; GO:0009410; GO:0009653; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030182; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0098797; GO:2001241 8797 XM_044307845.1 0 0 0 16 0 NA NA NA NA NA NA 8798 XM_029348852.2 740 857 580 479 208 O75081 1.32e-130 Protein CBFA2T3 (MTG8-related protein 2) (Myeloid translocation gene on chromosome 16 protein) (hMTG16) (Zinc finger MYND domain-containing protein 4) Homo sapiens (Human) granulocyte differentiation [GO:0030851]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of glycolytic process [GO:0045820]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; regulation of aerobic respiration [GO:1903715]; response to hypoxia [GO:0001666] GO:0000139; GO:0001666; GO:0003714; GO:0005634; GO:0005654; GO:0005730; GO:0008285; GO:0030851; GO:0032436; GO:0045820; GO:0045892; GO:0046872; GO:1903715 8799 XR_006395808.1 0 21 0 11 0 NA NA NA NA NA NA 8800 XM_044326219.1 1 1 11 12 20 NA NA NA NA NA NA 8801 XM_044322196.1 7 0 16 2 0 C6KFA3 3.96e-22 Adhesion G-protein coupled receptor G6 (G-protein coupled receptor 126) [Cleaved into: ADGRG6 N-terminal fragment (ADGRG6-NTF); ADGRG6 C-terminal fragment (ADGRG6-CTF)] Danio rerio (Zebrafish) (Brachydanio rerio) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cAMP-mediated signaling [GO:0019933]; cell surface receptor signaling pathway [GO:0007166]; ear development [GO:0043583]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; heart trabecula formation [GO:0060347]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; myelination of posterior lateral line nerve axons [GO:0048932]; ossification [GO:0001503]; peripheral nervous system myelin formation [GO:0032290]; regulation of sprouting angiogenesis [GO:1903670]; Schwann cell differentiation [GO:0014037]; semicircular canal fusion [GO:0060879] GO:0001503; GO:0004930; GO:0005518; GO:0005886; GO:0007005; GO:0007166; GO:0007186; GO:0007189; GO:0007507; GO:0014037; GO:0019933; GO:0022011; GO:0032290; GO:0042552; GO:0043236; GO:0043583; GO:0048932; GO:0050840; GO:0060347; GO:0060879; GO:1903670 8802 XM_029330353.2 205 452 341 208 249 NA NA NA NA NA NA 8803 XM_029333557.2 8 58 105 79 102 B5DF45 1.63e-65 TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6) Rattus norvegicus (Rat) activation of NF-kappaB-inducing kinase activity [GO:0007250]; activation of protein kinase activity [GO:0032147]; animal organ morphogenesis [GO:0009887]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; bone remodeling [GO:0046849]; bone resorption [GO:0045453]; cell development [GO:0048468]; cellular response to cytokine stimulus [GO:0071345]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-17-mediated signaling pathway [GO:0097400]; JNK cascade [GO:0007254]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin production [GO:0002637]; response to interleukin-1 [GO:0070555]; response to ischemia [GO:0002931]; signal transduction [GO:0007165]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000122; GO:0000209; GO:0001503; GO:0001701; GO:0001843; GO:0002637; GO:0002726; GO:0002931; GO:0004842; GO:0005164; GO:0005634; GO:0005737; GO:0005811; GO:0005829; GO:0005886; GO:0005938; GO:0006955; GO:0006974; GO:0007165; GO:0007249; GO:0007250; GO:0007254; GO:0008270; GO:0009887; GO:0009898; GO:0016567; GO:0019221; GO:0019886; GO:0019901; GO:0030316; GO:0031435; GO:0031624; GO:0031625; GO:0031666; GO:0031996; GO:0032147; GO:0032735; GO:0032743; GO:0032755; GO:0032813; GO:0032991; GO:0033209; GO:0035631; GO:0042088; GO:0042102; GO:0042475; GO:0042802; GO:0042826; GO:0042981; GO:0043011; GO:0043122; GO:0043123; GO:0043422; GO:0043507; GO:0045453; GO:0045672; GO:0045892; GO:0045944; GO:0046330; GO:0046849; GO:0047485; GO:0048468; GO:0048471; GO:0048661; GO:0050852; GO:0051091; GO:0051092; GO:0051865; GO:0061630; GO:0070498; GO:0070534; GO:0070555; GO:0071222; GO:0071345; GO:0097400; GO:1901224; GO:1904996; GO:2000679 8804 XR_003825697.2 89 41 39 34 93 NA NA NA NA NA NA 8805 XM_044314815.1 5 0 23 1 25 NA NA NA NA NA NA 8806 XM_044324434.1 359 291 103 169 331 NA NA NA NA NA NA 8807 XM_044308921.1 292 2 47 84 290 NA NA NA NA NA NA 8808 XM_044325544.1 6 2 5 0 0 NA NA NA NA NA NA 8809 XM_029328615.2 526 64 356 455 184 F1Q4S1 0 Probable phospholipid-transporting ATPase IIB (EC 7.6.2.1) (ATPase class II type 9B) Danio rerio (Zebrafish) (Brachydanio rerio) endocytosis [GO:0006897]; phospholipid translocation [GO:0045332]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] GO:0000287; GO:0005524; GO:0005768; GO:0005802; GO:0005886; GO:0006890; GO:0006897; GO:0016887; GO:0045332; GO:0140326 8810 XR_003826732.2 222 284 109 232 229 NA NA NA NA NA NA 8811 XM_029353530.2 341 353 35 575 27 NA NA NA NA NA NA 8812 XM_029331495.2 383 416 291 412 158 O14770 1.49e-113 Homeobox protein Meis2 (Meis1-related protein 1) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; brain development [GO:0007420]; embryonic pattern specification [GO:0009880]; eye development [GO:0001654]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas development [GO:0031016]; positive regulation of cardiac muscle myoblast proliferation [GO:0110024]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; response to growth factor [GO:0070848]; response to mechanical stimulus [GO:0009612]; visual learning [GO:0008542] GO:0000122; GO:0000785; GO:0000978; GO:0000981; GO:0001228; GO:0001654; GO:0003677; GO:0005634; GO:0006357; GO:0007420; GO:0008134; GO:0008284; GO:0008542; GO:0009612; GO:0009880; GO:0009887; GO:0031016; GO:0043565; GO:0045638; GO:0045931; GO:0045944; GO:0048471; GO:0070848; GO:0110024; GO:1990837 8813 XM_044309975.1 0 0 0 1 36 NA NA NA NA NA NA 8814 XR_006396724.1 0 0 0 9 0 NA NA NA NA NA NA 8815 XM_029326017.2 404 239 206 402 249 NA NA NA NA NA NA 8816 XM_044325654.1 33 0 26 0 0 NA NA NA NA NA NA 8817 XM_044327753.1 15 6 0 57 39 NA NA NA NA NA NA 8818 XM_029336571.2 62 88 66 60 134 A7MBC7 5.16e-52 Nuclear envelope integral membrane protein 1 Bos taurus (Bovine) nuclear membrane organization [GO:0071763] GO:0005635; GO:0005637; GO:0071763 8819 XM_029357232.2 0 101 70 115 52 Q9ES08 2.72e-24 Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3) (Two pore potassium channel KT3.2) (Two pore K(+) channel KT3.2) Rattus norvegicus (Rat) potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of ion transmembrane transport [GO:0034765]; stabilization of membrane potential [GO:0030322] GO:0005249; GO:0005267; GO:0005886; GO:0006813; GO:0008021; GO:0015271; GO:0022841; GO:0030322; GO:0034765; GO:0071805; GO:1990573 8820 XR_006397757.1 0 0 0 6 5 NA NA NA NA NA NA 8821 XM_029351991.2 8750 5684 2787 7525 5652 P13607 0 Sodium/potassium-transporting ATPase subunit alpha (Na(+)/K(+) ATPase alpha subunit) (EC 7.2.2.13) (Sodium pump subunit alpha) Drosophila melanogaster (Fruit fly) adult locomotory behavior [GO:0008344]; cation transport [GO:0006812]; cellular potassium ion homeostasis [GO:0030007]; cellular sodium ion homeostasis [GO:0006883]; chemical synaptic transmission [GO:0007268]; determination of adult lifespan [GO:0008340]; jump response [GO:0007630]; locomotory behavior [GO:0007626]; neuromuscular process [GO:0050905]; potassium ion import across plasma membrane [GO:1990573]; proton transmembrane transport [GO:1902600]; regulation of tube diameter, open tracheal system [GO:0035158]; regulation of tube length, open tracheal system [GO:0035159]; response to mechanical stimulus [GO:0009612]; response to temperature stimulus [GO:0009266]; sensory perception of sound [GO:0007605]; septate junction assembly [GO:0019991]; sodium ion export across plasma membrane [GO:0036376]; synaptic assembly at neuromuscular junction [GO:0051124]; tissue homeostasis [GO:0001894]; trachea morphogenesis [GO:0060439] GO:0001894; GO:0005391; GO:0005524; GO:0005634; GO:0005737; GO:0005886; GO:0005890; GO:0005918; GO:0006812; GO:0006883; GO:0007268; GO:0007605; GO:0007626; GO:0007630; GO:0008340; GO:0008344; GO:0009266; GO:0009612; GO:0016323; GO:0016887; GO:0019829; GO:0019991; GO:0030007; GO:0035158; GO:0035159; GO:0036376; GO:0045202; GO:0050905; GO:0051124; GO:0060439; GO:1902600; GO:1990573 8822 XM_044328292.1 79 47 28 53 39 E7F7V7 7.67e-24 Galanin receptor 2b Danio rerio (Zebrafish) (Brachydanio rerio) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; neuropeptide signaling pathway [GO:0007218] GO:0004966; GO:0005886; GO:0007188; GO:0007218; GO:0008528 8823 XM_044328301.1 840 280 197 654 568 Q6NVC5 0 Mitochondrial Rho GTPase 1-A (MIRO-1-A) (EC 3.6.5.-) (Ras homolog gene family member T1-A) Danio rerio (Zebrafish) (Brachydanio rerio) cellular homeostasis [GO:0019725]; mitochondrial outer membrane permeabilization [GO:0097345]; mitochondrion organization [GO:0007005]; mitochondrion transport along microtubule [GO:0047497]; regulation of mitochondrion organization [GO:0010821]; small GTPase mediated signal transduction [GO:0007264] GO:0003924; GO:0005509; GO:0005525; GO:0005739; GO:0005741; GO:0007005; GO:0007264; GO:0010821; GO:0019725; GO:0047497; GO:0097345 8824 XM_029355916.2 510 384 304 402 344 P00520 0 Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150) Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; actin filament polymerization [GO:0030041]; activated T cell proliferation [GO:0050798]; activation of protein kinase C activity [GO:1990051]; alpha-beta T cell differentiation [GO:0046632]; associative learning [GO:0008306]; autophagy [GO:0006914]; B cell proliferation [GO:0042100]; B cell proliferation involved in immune response [GO:0002322]; B cell receptor signaling pathway [GO:0050853]; B-1 B cell homeostasis [GO:0001922]; Bergmann glial cell differentiation [GO:0060020]; BMP signaling pathway [GO:0030509]; cardiac muscle cell proliferation [GO:0060038]; cell-cell adhesion [GO:0098609]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cellular senescence [GO:0090398]; cerebellum morphogenesis [GO:0021587]; circulatory system development [GO:0072359]; DN4 thymocyte differentiation [GO:1904157]; DNA conformation change [GO:0071103]; DNA repair [GO:0006281]; endocytosis [GO:0006897]; endothelial cell migration [GO:0043542]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; integrin-mediated signaling pathway [GO:0007229]; learning or memory [GO:0007611]; microspike assembly [GO:0030035]; myoblast proliferation [GO:0051450]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cellular senescence [GO:2000773]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phospholipase C activity [GO:1900275]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; neural tube closure [GO:0001843]; neuroepithelial cell differentiation [GO:0060563]; neuromuscular process controlling balance [GO:0050885]; neuron death [GO:0070997]; neuron differentiation [GO:0030182]; neuropilin signaling pathway [GO:0038189]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; podocyte apoptotic process [GO:1903210]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament binding [GO:1904531]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel branching [GO:1905555]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of dendrite development [GO:1900006]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of extracellular matrix organization [GO:1903055]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of hydrogen peroxide-mediated programmed cell death [GO:1901300]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of microtubule binding [GO:1904528]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of T cell migration [GO:2000406]; positive regulation of type II interferon production [GO:0032729]; positive regulation of vasoconstriction [GO:0045907]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein localization to cytoplasmic microtubule plus-end [GO:1904518]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of apoptotic process [GO:0042981]; regulation of axon extension [GO:0030516]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of cellular senescence [GO:2000772]; regulation of extracellular matrix organization [GO:1903053]; regulation of microtubule polymerization [GO:0031113]; regulation of modification of synaptic structure [GO:1905244]; regulation of response to DNA damage stimulus [GO:2001020]; regulation of T cell differentiation [GO:0045580]; response to endoplasmic reticulum stress [GO:0034976]; response to epinephrine [GO:0071871]; response to oxidative stress [GO:0006979]; response to xenobiotic stimulus [GO:0009410]; signal transduction in response to DNA damage [GO:0042770]; spleen development [GO:0048536]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; transitional one stage B cell differentiation [GO:0002333] GO:0000287; GO:0000400; GO:0000405; GO:0001726; GO:0001784; GO:0001843; GO:0001922; GO:0001934; GO:0002322; GO:0002333; GO:0004672; GO:0004713; GO:0004715; GO:0005080; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005739; GO:0005783; GO:0005829; GO:0006281; GO:0006468; GO:0006897; GO:0006909; GO:0006914; GO:0006974; GO:0006979; GO:0007173; GO:0007204; GO:0007229; GO:0007249; GO:0007611; GO:0008022; GO:0008306; GO:0009410; GO:0009791; GO:0010595; GO:0015629; GO:0016301; GO:0016604; GO:0017124; GO:0018108; GO:0019901; GO:0019904; GO:0019905; GO:0021587; GO:0022408; GO:0030035; GO:0030036; GO:0030041; GO:0030145; GO:0030182; GO:0030425; GO:0030426; GO:0030509; GO:0030514; GO:0030516; GO:0031113; GO:0031252; GO:0032489; GO:0032729; GO:0032743; GO:0032956; GO:0032991; GO:0033690; GO:0034446; GO:0034976; GO:0035791; GO:0038083; GO:0038189; GO:0038191; GO:0042100; GO:0042127; GO:0042169; GO:0042770; GO:0042981; GO:0043005; GO:0043025; GO:0043065; GO:0043123; GO:0043124; GO:0043525; GO:0043542; GO:0043621; GO:0045202; GO:0045580; GO:0045907; GO:0045930; GO:0045931; GO:0046632; GO:0046777; GO:0046875; GO:0048008; GO:0048146; GO:0048471; GO:0048536; GO:0048538; GO:0050731; GO:0050798; GO:0050852; GO:0050853; GO:0050885; GO:0051015; GO:0051019; GO:0051281; GO:0051353; GO:0051444; GO:0051450; GO:0051496; GO:0051649; GO:0051726; GO:0051894; GO:0060020; GO:0060038; GO:0060563; GO:0070064; GO:0070097; GO:0070301; GO:0070371; GO:0070373; GO:0070374; GO:0070997; GO:0071103; GO:0071222; GO:0071560; GO:0071871; GO:0071901; GO:0072359; GO:0090050; GO:0090398; GO:0098609; GO:1900006; GO:1900026; GO:1900272; GO:1900275; GO:1901216; GO:1901300; GO:1903053; GO:1903055; GO:1903210; GO:1903905; GO:1904157; GO:1904518; GO:1904528; GO:1904531; GO:1905244; GO:1905555; GO:1990051; GO:1990837; GO:2000096; GO:2000251; GO:2000352; GO:2000406; GO:2000772; GO:2000773; GO:2001020 8825 XM_044307623.1 143 15 76 89 111 NA NA NA NA NA NA 8826 XM_044314104.1 532 840 235 225 252 P48800 8.15e-25 Fibroblast growth factor 2 (FGF-2) (Basic fibroblast growth factor) (bFGF) (Heparin-binding growth factor 2) (HBGF-2) Gallus gallus (Chicken) angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; brain development [GO:0007420]; cell differentiation [GO:0030154]; cell division [GO:0051301]; cell population proliferation [GO:0008283]; epicardial cell to mesenchymal cell transition [GO:0003347]; fibroblast growth factor receptor signaling pathway [GO:0008543]; growth factor dependent regulation of skeletal muscle satellite cell proliferation [GO:0014843]; inner ear receptor cell differentiation involved in inner ear sensory epithelium regeneration [GO:0070660]; lens morphogenesis in camera-type eye [GO:0002089]; lung development [GO:0030324]; mesoderm formation [GO:0001707]; metanephric podocyte differentiation [GO:0072248]; neural retina development [GO:0003407]; neuroepithelial cell differentiation [GO:0060563]; neurogenesis [GO:0022008]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of plasminogen activation [GO:0010756]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell migration [GO:0030334]; stem cell proliferation [GO:0072089]; tissue homeostasis [GO:0001894]; wound healing [GO:0042060] GO:0001525; GO:0001707; GO:0001894; GO:0001934; GO:0002089; GO:0003347; GO:0003407; GO:0005104; GO:0005178; GO:0005615; GO:0005634; GO:0005730; GO:0005737; GO:0005829; GO:0007420; GO:0008083; GO:0008201; GO:0008283; GO:0008284; GO:0008543; GO:0009887; GO:0010595; GO:0010628; GO:0010756; GO:0014843; GO:0022008; GO:0030154; GO:0030324; GO:0030334; GO:0042060; GO:0043406; GO:0043536; GO:0045766; GO:0045944; GO:0050679; GO:0051301; GO:0051781; GO:0060563; GO:0070660; GO:0072089; GO:0072248; GO:0090050 8827 XM_044328008.1 0 0 24 3 10 O15457 0 MutS protein homolog 4 (hMSH4) Homo sapiens (Human) female gamete generation [GO:0007292]; homologous chromosome pairing at meiosis [GO:0007129]; mismatch repair [GO:0006298]; ovarian follicle development [GO:0001541]; reciprocal meiotic recombination [GO:0007131]; spermatogenesis [GO:0007283] GO:0000795; GO:0001541; GO:0003677; GO:0003690; GO:0005524; GO:0005634; GO:0005694; GO:0005713; GO:0006298; GO:0007129; GO:0007131; GO:0007283; GO:0007292; GO:0030983; GO:0140664 8828 XM_044321290.1 0 34 8 30 0 A6QLD2 5.84e-52 Olfactomedin-like protein 2B Bos taurus (Bovine) extracellular matrix organization [GO:0030198]; signal transduction [GO:0007165] GO:0005615; GO:0007165; GO:0030198; GO:0031012; GO:0042802; GO:0050840 8829 XM_044310956.1 14 44 30 9 32 P08419 3.86e-53 Chymotrypsin-like elastase family member 2A (EC 3.4.21.71) (Elastase-2) (Elastase-2A) Sus scrofa (Pig) insulin catabolic process [GO:1901143]; proteolysis [GO:0006508]; regulation of insulin secretion [GO:0050796]; regulation of platelet aggregation [GO:0090330]; response to insulin [GO:0032868] GO:0004175; GO:0004252; GO:0005576; GO:0005615; GO:0006508; GO:0032868; GO:0050796; GO:0090330; GO:1901143 8830 XM_044312790.1 0 17 13 0 0 NA NA NA NA NA NA 8831 XR_006395257.1 3 3 24 23 71 NA NA NA NA NA NA 8832 XM_029337217.2 14 0 0 0 0 A1L2H9 2.08e-65 Replication protein A 32 kDa subunit-B (RP-A p32) (Replication factor A protein 2) (RF-A protein 2) (Replication protein A 34 kDa subunit) (RP-A p34) Xenopus laevis (African clawed frog) base-excision repair [GO:0006284]; DNA replication [GO:0006260]; DNA replication checkpoint signaling [GO:0000076]; double-strand break repair via homologous recombination [GO:0000724]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; protein localization to chromosome [GO:0034502]; regulation of DNA damage checkpoint [GO:2000001]; telomere maintenance [GO:0000723] GO:0000076; GO:0000723; GO:0000724; GO:0000785; GO:0003684; GO:0003697; GO:0005634; GO:0005662; GO:0006260; GO:0006284; GO:0006289; GO:0006298; GO:0016605; GO:0034502; GO:2000001 8833 XM_029346085.2 1287 1160 762 1942 2271 Q5EAB6 8.92e-180 Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGnT1) (EC 2.4.1.-) Bos taurus (Bovine) O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493] GO:0000139; GO:0006493; GO:0008375; GO:0016020; GO:0016266; GO:0030145 8834 XM_044311000.1 82 0 3 39 48 B8V7P3 7.41e-74 Putative carbonic anhydrase (EC 4.2.1.1) (Carbonate dehydratase) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0004089; GO:0005576; GO:0008270 8835 XR_006394272.1 0 0 11 0 1 NA NA NA NA NA NA 8836 XM_029340484.2 6467 5965 3879 7040 7410 Q4V7C7 0 Actin-related protein 3 (Actin-like protein 3) Rattus norvegicus (Rat) Arp2/3 complex-mediated actin nucleation [GO:0034314]; astrocyte differentiation [GO:0048708]; asymmetric cell division [GO:0008356]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to interleukin-1 [GO:0071347]; cellular response to pyrimidine ribonucleotide [GO:1905835]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cellular response to trichostatin A [GO:0035984]; cellular response to triterpenoid [GO:1905837]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to type II interferon [GO:0071346]; cilium assembly [GO:0060271]; establishment or maintenance of cell polarity [GO:0007163]; meiotic cell cycle [GO:0051321]; meiotic chromosome movement towards spindle pole [GO:0016344]; meiotic cytokinesis [GO:0033206]; negative regulation of axon extension [GO:0030517]; negative regulation of bleb assembly [GO:1904171]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of synapse assembly [GO:0051965]; positive regulation of transcription by RNA polymerase II [GO:0045944]; postsynapse organization [GO:0099173]; postsynaptic actin cytoskeleton organization [GO:0098974]; regulation of myosin II filament organization [GO:0043519]; response to estradiol [GO:0032355]; response to heparin [GO:0071503]; Sertoli cell barrier remodeling [GO:0061843]; spermatogenesis [GO:0007283]; spindle localization [GO:0051653] GO:0000139; GO:0001726; GO:0002102; GO:0003779; GO:0005200; GO:0005524; GO:0005634; GO:0005737; GO:0005885; GO:0005903; GO:0005911; GO:0007163; GO:0007283; GO:0008356; GO:0010592; GO:0010763; GO:0016344; GO:0030027; GO:0030056; GO:0030517; GO:0030838; GO:0031252; GO:0032092; GO:0032355; GO:0033206; GO:0034314; GO:0035861; GO:0035984; GO:0043519; GO:0045666; GO:0045944; GO:0048471; GO:0048708; GO:0048711; GO:0050775; GO:0051117; GO:0051321; GO:0051491; GO:0051653; GO:0051965; GO:0060076; GO:0060271; GO:0061003; GO:0061825; GO:0061828; GO:0061830; GO:0061831; GO:0061832; GO:0061843; GO:0061851; GO:0071346; GO:0071347; GO:0071356; GO:0071364; GO:0071503; GO:0071560; GO:0090314; GO:0098794; GO:0098974; GO:0098978; GO:0099173; GO:1903078; GO:1904171; GO:1905835; GO:1905837; GO:2000251 8837 XM_044320650.1 28 0 0 0 0 NA NA NA NA NA NA 8838 XM_029347388.2 1332 844 778 1240 1541 O94868 4.43e-99 F-BAR and double SH3 domains protein 2 (Carom) (Protein nervous wreck 1) (NWK1) (SH3 multiple domains protein 3) Homo sapiens (Human) clathrin-dependent endocytosis [GO:0072583]; membrane organization [GO:0061024]; neuromuscular synaptic transmission [GO:0007274]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601]; protein transport [GO:0015031]; regulation of actin filament polymerization [GO:0030833] GO:0005547; GO:0005886; GO:0005905; GO:0007274; GO:0015031; GO:0030833; GO:0030838; GO:0031594; GO:0043325; GO:0055037; GO:0061024; GO:0070161; GO:0072583; GO:0120043; GO:2000601 8839 XM_029349242.2 189 204 152 150 233 Q5I0K3 5e-99 Citramalyl-CoA lyase, mitochondrial (EC 4.1.3.25) ((3S)-malyl-CoA thioesterase) (EC 3.1.2.30) (Beta-methylmalate synthase) (EC 2.3.3.-) (Citrate lyase subunit beta-like protein, mitochondrial) (Citrate lyase beta-like) (Malate synthase) (EC 2.3.3.9) Rattus norvegicus (Rat) positive regulation of cobalamin metabolic process [GO:0106121]; protein homotrimerization [GO:0070207]; regulation of cobalamin metabolic process [GO:0106064] GO:0000287; GO:0004474; GO:0005739; GO:0016787; GO:0047777; GO:0070207; GO:0106064; GO:0106121 8840 XM_029339438.2 44 12 13 100 90 NA NA NA NA NA NA 8841 XM_029350242.2 52 2216 715 964 1970 Q28IE5 2.92e-137 Omega-amidase NIT2 (EC 3.5.1.3) (Nitrilase homolog 2) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) nitrogen compound metabolic process [GO:0006807] GO:0005737; GO:0006807; GO:0050152; GO:0106008 8842 XM_029324377.2 72 23 0 0 4 Q4QQY7 0 Queuine tRNA-ribosyltransferase catalytic subunit 1 (EC 2.4.2.64) (Guanine insertion enzyme) (tRNA-guanine transglycosylase) Xenopus laevis (African clawed frog) tRNA-guanine transglycosylation [GO:0101030] GO:0005741; GO:0008479; GO:0042803; GO:0046872; GO:0046982; GO:0101030 8843 XM_029357727.2 917 748 549 672 1085 NA NA NA NA NA NA 8844 XM_029343812.2 0 1 1 14 11 NA NA NA NA NA NA 8845 XM_044310343.1 19 0 22 7 4 NA NA NA NA NA NA 8846 XM_044309019.1 213 163 70 132 219 P20664 4.99e-161 DNA primase small subunit (EC 2.7.7.102) (DNA primase 49 kDa subunit) (p49) Mus musculus (Mouse) DNA replication initiation [GO:0006270]; DNA replication, synthesis of RNA primer [GO:0006269] GO:0000287; GO:0003896; GO:0005658; GO:0006269; GO:0006270; GO:0008270; GO:0032553 8847 XM_029342710.2 0 1 7 4 0 NA NA NA NA NA NA 8848 XM_029325174.2 1945 1538 1168 1982 1783 P33005 1.69e-27 Anosmin-1 (Kallmann syndrome protein homolog) Gallus gallus (Chicken) cell adhesion [GO:0007155]; negative regulation of peptidase activity [GO:0010466]; neuron differentiation [GO:0030182] GO:0004867; GO:0005576; GO:0007155; GO:0009986; GO:0010466; GO:0030182 8849 XM_044316040.1 94 66 94 66 135 NA NA NA NA NA NA 8850 XM_044311316.1 9 1 90 11 203 NA NA NA NA NA NA 8851 XM_029339778.2 112 83 61 130 124 NA NA NA NA NA NA 8852 XM_044319904.1 34 0 0 67 0 Q5ZI16 6.15e-48 tRNA-specific adenosine deaminase 1 (EC 3.5.4.34) (tRNA-specific adenosine-37 deaminase) Gallus gallus (Chicken) tRNA processing [GO:0008033] GO:0003723; GO:0008033; GO:0008251; GO:0046872 8853 XM_044319196.1 3 0 0 24 24 NA NA NA NA NA NA 8854 XM_029357482.2 744 759 783 1039 546 NA NA NA NA NA NA 8855 XM_044321955.1 747 213 643 506 706 NA NA NA NA NA NA 8856 XM_029354629.2 2 99 75 36 52 NA NA NA NA NA NA 8857 XM_044308472.1 0 0 0 0 55 NA NA NA NA NA NA 8858 XM_044321784.1 6 17 5 166 4 NA NA NA NA NA NA 8859 XM_044322917.1 419 233 373 159 574 NA NA NA NA NA NA 8860 XM_044327743.1 0 4 0 0 10 NA NA NA NA NA NA 8861 XM_044322434.1 0 0 11 8 4 NA NA NA NA NA NA 8862 XM_029356003.2 162 36 54 61 160 NA NA NA NA NA NA 8863 XM_044313099.1 280 423 139 448 71 NA NA NA NA NA NA 8864 XM_044308828.1 388 47 75 176 58 Q95LR0 3.57e-34 Cilia- and flagella-associated protein 91 (CFAP91) (AMY-1-associating protein expressed in testis 1) (AAT-1) (MYCBP/AMY-1-associated testis-expressed protein 1) (Protein MAATS1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) axonemal central apparatus assembly [GO:1904158]; cell differentiation [GO:0030154]; cilium movement [GO:0003341]; spermatogenesis [GO:0007283] GO:0003341; GO:0005739; GO:0005930; GO:0007283; GO:0030154; GO:0031514; GO:1904158 8865 XM_029353373.2 257 172 188 92 289 Q96AY4 7.44e-65 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8866 XM_029353373.2 257 172 188 92 289 Q96AY4 2.22e-64 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8867 XM_029353373.2 257 172 188 92 289 Q96AY4 1.27e-62 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8868 XM_029353373.2 257 172 188 92 289 Q96AY4 1.05e-60 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8869 XM_029353373.2 257 172 188 92 289 Q96AY4 3.78e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8870 XM_029353373.2 257 172 188 92 289 Q96AY4 7.07e-53 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8871 XM_029353373.2 257 172 188 92 289 Q96AY4 2.54e-49 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8872 XM_029353373.2 257 172 188 92 289 Q96AY4 1.27e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8873 XM_044328877.1 117 2 125 12 33 NA NA NA NA NA NA 8874 XR_003827311.2 32 30 8 77 30 NA NA NA NA NA NA 8875 XM_044324463.1 0 4 1 47 5 NA NA NA NA NA NA 8876 XM_029332231.2 242 193 270 245 167 Q805E5 1.97e-80 Carbohydrate sulfotransferase 14 (EC 2.8.2.-) (Dermatan 4-sulfotransferase 1) (D4ST-1) (zD4ST-1) Danio rerio (Zebrafish) (Brachydanio rerio) carbohydrate biosynthetic process [GO:0016051]; dermatan sulfate proteoglycan metabolic process [GO:0050655] GO:0000139; GO:0001537; GO:0008146; GO:0016051; GO:0050655 8877 XM_029349176.2 820 677 289 613 803 NA NA NA NA NA NA 8878 XR_006391328.1 1 20 34 18 2 NA NA NA NA NA NA 8879 XM_044312006.1 44 42 7 7 21 NA NA NA NA NA NA 8880 XR_003826640.2 0 0 24 4 25 NA NA NA NA NA NA 8881 XM_044322086.1 596 425 309 601 616 Q8N4P6 1.27e-72 Leucine-rich repeat-containing protein 71 Homo sapiens (Human) NA NA 8882 XM_044307902.1 0 2 0 14 20 NA NA NA NA NA NA 8883 XM_029328519.2 95 101 125 111 337 Q05927 6.75e-120 5'-nucleotidase (5'-NT) (EC 3.1.3.35) (EC 3.1.3.5) (EC 3.1.3.89) (EC 3.1.3.91) (EC 3.1.3.99) (5'-deoxynucleotidase) (Ecto-5'-nucleotidase) (IMP-specific 5'-nucleotidase) (Thymidylate 5'-phosphatase) (CD antigen CD73) Bos taurus (Bovine) nucleotide catabolic process [GO:0009166] GO:0000166; GO:0005886; GO:0008253; GO:0009166; GO:0016020; GO:0042802; GO:0046872; GO:0050340; GO:0050483; GO:0050484; GO:0106411 8884 XM_044317850.1 874 629 626 884 762 Q5RIW8 0 Mediator of RNA polymerase II transcription subunit 23 (Cofactor required for Sp1 transcriptional activation subunit 3) (CRSP complex subunit 3) (Mediator complex subunit 23) Danio rerio (Zebrafish) (Brachydanio rerio) circulatory system development [GO:0072359]; negative regulation of neurogenesis [GO:0050768]; pigmentation [GO:0043473]; positive regulation of gene expression [GO:0010628]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0005667; GO:0006357; GO:0010628; GO:0016592; GO:0043473; GO:0050768; GO:0072359 8885 XM_044321791.1 0 0 0 179 0 Q66JY2 6.95e-39 INO80 complex subunit D Mus musculus (Mouse) chromatin remodeling [GO:0006338]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of telomere maintenance in response to DNA damage [GO:1904507]; regulation of cell cycle [GO:0051726]; regulation of chromosome organization [GO:0033044]; regulation of DNA repair [GO:0006282]; regulation of DNA replication [GO:0006275]; regulation of DNA strand elongation [GO:0060382]; regulation of embryonic development [GO:0045995]; telomere maintenance [GO:0000723] GO:0000723; GO:0005634; GO:0006275; GO:0006281; GO:0006282; GO:0006310; GO:0006338; GO:0031011; GO:0033044; GO:0045739; GO:0045893; GO:0045995; GO:0051726; GO:0060382; GO:1904507 8886 XR_003824118.2 218 158 169 94 283 NA NA NA NA NA NA 8887 XM_044322655.1 596 451 306 242 195 Q8QZX5 3.4e-25 U7 snRNA-associated Sm-like protein LSm10 Mus musculus (Mouse) mRNA 3'-end processing by stem-loop binding and cleavage [GO:0006398]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; RNA splicing [GO:0008380] GO:0005654; GO:0005683; GO:0006398; GO:0008380; GO:0015030; GO:0016604; GO:0017069; GO:0071208; GO:0071209; GO:0071254; GO:1900087 8888 XM_044328473.1 988 720 491 968 888 B1AQJ2 9.96e-134 Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.4.19.12) (Deubiquitinating enzyme 36) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) Mus musculus (Mouse) histone deubiquitination [GO:0016578]; negative regulation of macroautophagy [GO:0016242]; nucleolus organization [GO:0007000]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of apoptotic process [GO:0042981]; regulation of protein stability [GO:0031647]; regulation of rRNA processing [GO:2000232]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004197; GO:0004843; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0006511; GO:0007000; GO:0016242; GO:0016578; GO:0016579; GO:0016607; GO:0031647; GO:0042981; GO:0050821; GO:2000232 8889 XM_029356283.2 9 5 0 19 15 Q58A42 5.69e-63 Protein DD3-3 Dictyostelium discoideum (Social amoeba) NA GO:0016020 8890 XR_006392296.1 184 46 48 51 637 NA NA NA NA NA NA 8891 XM_029324586.2 28 9 7 7 20 NA NA NA NA NA NA 8892 XM_029343844.2 68 788 46 71 58 NA NA NA NA NA NA 8893 XM_044324934.1 2 4 0 6 6 NA NA NA NA NA NA 8894 XM_029330605.2 12 78 0 279 280 NA NA NA NA NA NA 8895 XM_044314914.1 102 172 52 17 146 NA NA NA NA NA NA 8896 XM_044319512.1 3698 2635 31 45 2407 Q5R9T9 5.22e-46 Guanylate-binding protein 6 (EC 3.6.5.-) (GTP-binding protein 6) (GBP-6) (Guanine nucleotide-binding protein 6) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cellular response to type II interferon [GO:0071346]; defense response to bacterium [GO:0042742]; immune response [GO:0006955] GO:0003924; GO:0005525; GO:0006955; GO:0031410; GO:0042742; GO:0071346 8897 XM_029343516.2 12 0 36 0 28 NA NA NA NA NA NA 8898 XM_029335612.2 2161 1175 1092 1699 945 O95372 2.8e-78 Acyl-protein thioesterase 2 (APT-2) (EC 3.1.2.-) (Lysophospholipase II) (LPL-II) (LysoPLA II) (Palmitoyl-protein hydrolase) (EC 3.1.2.22) Homo sapiens (Human) acylglycerol catabolic process [GO:0046464]; axon guidance [GO:0007411]; fatty acid metabolic process [GO:0006631]; prostaglandin catabolic process [GO:1905344]; protein depalmitoylation [GO:0002084] GO:0002084; GO:0004622; GO:0005737; GO:0005795; GO:0005829; GO:0006631; GO:0007411; GO:0008474; GO:0045296; GO:0046464; GO:0070062; GO:1905344 8899 XM_044317179.1 13 105 116 45 217 NA NA NA NA NA NA 8900 XM_044324487.1 15 18 1 0 15 Q80XJ3 1.09e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 8901 XM_044314949.1 41 27 21 31 52 NA NA NA NA NA NA 8902 XM_044318400.1 1 0 18 0 26 NA NA NA NA NA NA 8903 XM_029325343.2 0 0 5 36 24 NA NA NA NA NA NA 8904 XM_044317998.1 39 141 13 66 66 NA NA NA NA NA NA 8905 XM_044309823.1 106 130 0 0 5 NA NA NA NA NA NA 8906 XM_029339749.2 168 48 159 268 101 O88609 3.58e-72 LIM homeobox transcription factor 1-beta (LIM/homeobox protein 1.2) (LMX-1.2) (LIM/homeobox protein LMX1B) Mus musculus (Mouse) camera-type eye development [GO:0043010]; cell population proliferation [GO:0008283]; central nervous system neuron development [GO:0021954]; cerebellum morphogenesis [GO:0021587]; collagen fibril organization [GO:0030199]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral pattern formation [GO:0009953]; embryonic limb morphogenesis [GO:0030326]; limb morphogenesis [GO:0035108]; locomotory behavior [GO:0007626]; memory [GO:0007613]; midbrain development [GO:0030901]; neuron differentiation [GO:0030182]; neuron migration [GO:0001764]; olfactory behavior [GO:0042048]; organ growth [GO:0035265]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of autophagy [GO:0010506]; regulation of DNA-templated transcription [GO:0006355]; regulation of gene expression [GO:0010468]; regulation of intracellular transport [GO:0032386]; regulation of transcription by RNA polymerase II [GO:0006357]; synapse organization [GO:0050808]; trabecular meshwork development [GO:0002930] GO:0000977; GO:0000981; GO:0001228; GO:0001764; GO:0002930; GO:0003700; GO:0005634; GO:0006355; GO:0006357; GO:0007613; GO:0007626; GO:0008283; GO:0009953; GO:0010468; GO:0010506; GO:0021587; GO:0021954; GO:0030182; GO:0030199; GO:0030326; GO:0030901; GO:0032386; GO:0035108; GO:0035265; GO:0042048; GO:0043010; GO:0045944; GO:0046872; GO:0050808; GO:0071542; GO:1990837 8907 XM_029355716.2 0 17 5 14 0 NA NA NA NA NA NA 8908 XM_029334452.2 2488 814 875 1336 827 Q9UPV9 3.31e-56 Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase-interacting protein) (Protein Milton) Homo sapiens (Human) anterograde axonal transport of mitochondrion [GO:0098957]; endosome to lysosome transport [GO:0008333]; mitochondrion distribution [GO:0048311]; neurogenesis [GO:0022008]; protein O-linked glycosylation [GO:0006493]; protein targeting [GO:0006605]; regulation of transcription by RNA polymerase II [GO:0006357]; vesicle transport along microtubule [GO:0047496] GO:0005102; GO:0005634; GO:0005737; GO:0005739; GO:0005769; GO:0005829; GO:0005938; GO:0006357; GO:0006493; GO:0006605; GO:0008333; GO:0017022; GO:0022008; GO:0030425; GO:0031410; GO:0031966; GO:0047496; GO:0048311; GO:0050811; GO:0098957; GO:1904115 8909 XM_029346934.2 106 96 56 39 109 Q6KZM5 3.23e-22 Glutamate formimidoyltransferase (EC 2.1.2.5) (5-formyltetrahydrofolate cyclo-ligase) (EC 6.3.3.2) (Glutamate formiminotransferase) (Glutamate formyltransferase) Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828) histidine catabolic process to glutamate and formamide [GO:0019556]; histidine catabolic process to glutamate and formate [GO:0019557]; tetrahydrofolate interconversion [GO:0035999] GO:0005542; GO:0005737; GO:0019556; GO:0019557; GO:0030272; GO:0030409; GO:0035999 8910 XM_044315802.1 68 180 4 576 2 NA NA NA NA NA NA 8911 XM_029324636.2 252 75 73 160 138 Q4R918 5.87e-147 Kinesin-like protein KIF25 Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) establishment of spindle orientation [GO:0051294]; microtubule-based movement [GO:0007018]; negative regulation of mitotic centrosome separation [GO:0046603]; nucleus localization [GO:0051647]; protein homotetramerization [GO:0051289] GO:0005524; GO:0005737; GO:0005813; GO:0005874; GO:0007018; GO:0008017; GO:0008569; GO:0046603; GO:0051289; GO:0051294; GO:0051647 8912 XM_029356986.2 325 390 236 226 363 P30975 8.84e-22 Tachykinin-like peptides receptor 99D (Tachykinin-like receptor at 99D) (dTKR) Drosophila melanogaster (Fruit fly) detection of chemical stimulus involved in sensory perception of smell [GO:0050911]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; neuropeptide signaling pathway [GO:0007218]; olfactory behavior [GO:0042048]; positive regulation of sensory perception of pain [GO:1904058]; tachykinin receptor signaling pathway [GO:0007217] GO:0004995; GO:0005886; GO:0007186; GO:0007217; GO:0007218; GO:0008188; GO:0016020; GO:0042048; GO:0050805; GO:0050911; GO:1904058 8913 XM_029343674.2 6951 4996 5086 7109 5373 B0FYY4 1.3e-173 Integrin beta-1 (Fibronectin receptor subunit beta) (Integrin subunit beta-1) (VLA-4 subunit beta) (CD antigen CD29) Ovis aries (Sheep) cell adhesion mediated by integrin [GO:0033627]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; integrin-mediated signaling pathway [GO:0007229]; muscle organ development [GO:0007517]; myoblast differentiation [GO:0045445]; myoblast fusion [GO:0007520]; positive regulation of cell migration [GO:0030335]; positive regulation of protein localization to plasma membrane [GO:1903078]; receptor internalization [GO:0031623]; regulation of collagen catabolic process [GO:0010710] GO:0005925; GO:0007229; GO:0007517; GO:0007520; GO:0008305; GO:0009986; GO:0010710; GO:0016020; GO:0030027; GO:0030335; GO:0031623; GO:0032587; GO:0033627; GO:0042470; GO:0045445; GO:0046872; GO:0046982; GO:0055037; GO:0071404; GO:1903078 8914 XR_006391844.1 306 137 98 113 203 NA NA NA NA NA NA 8915 XM_044307301.1 139 126 85 96 100 NA NA NA NA NA NA 8916 XR_006394966.1 1612 1073 1286 1568 1456 Q76I79 1.32e-133 Protein phosphatase Slingshot homolog 1 (EC 3.1.3.16) (EC 3.1.3.48) (SSH-like protein 1) (SSH-1L) (mSSH-1L) Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; cell morphogenesis [GO:0000902]; cellular response to ATP [GO:0071318]; excitatory chemical synaptic transmission [GO:0098976]; negative regulation of actin filament polymerization [GO:0030837]; positive regulation of AMPA glutamate receptor clustering [GO:1904719]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neuron death [GO:1901216]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; protein dephosphorylation [GO:0006470]; regulation of protein metabolic process [GO:0051246] GO:0000902; GO:0003779; GO:0004721; GO:0004725; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0006470; GO:0008138; GO:0017018; GO:0030036; GO:0030426; GO:0030496; GO:0030837; GO:0031252; GO:0031915; GO:0032154; GO:0042995; GO:0045202; GO:0051246; GO:0071318; GO:0098976; GO:1901216; GO:1904719; GO:1904754; GO:2000463 8917 XM_044315888.1 0 0 1 0 12 NA NA NA NA NA NA 8918 XR_006395134.1 277 28 173 0 549 NA NA NA NA NA NA 8919 XM_029355429.2 18 21 20 35 53 Q99315 1.81e-57 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 8920 XM_044314811.1 50 27 52 88 0 NA NA NA NA NA NA 8921 XM_029324297.2 467 232 172 334 326 A5PN43 2.49e-40 Endosomal/lysosomal proton channel TMEM175 (Transmembrane protein 175) Danio rerio (Zebrafish) (Brachydanio rerio) lysosomal lumen pH elevation [GO:0035752]; neuron cellular homeostasis [GO:0070050]; phagosome-lysosome fusion [GO:0090385]; potassium ion transmembrane transport [GO:0071805]; proton transmembrane transport [GO:1902600]; regulation of lysosomal lumen pH [GO:0035751] GO:0005267; GO:0005764; GO:0005765; GO:0005768; GO:0010008; GO:0015252; GO:0022841; GO:0035751; GO:0035752; GO:0050544; GO:0070050; GO:0071805; GO:0090385; GO:1902600 8922 XM_044307740.1 15 2 14 11 53 Q9U6Y6 6.05e-109 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 8923 XM_044316524.1 106 0 26 1 5 NA NA NA NA NA NA 8924 XM_044322426.1 35 0 2 2 8 Q9H3D4 1.47e-37 Tumor protein 63 (p63) (Chronic ulcerative stomatitis protein) (CUSP) (Keratinocyte transcription factor KET) (Transformation-related protein 63) (TP63) (Tumor protein p73-like) (p73L) (p40) (p51) Homo sapiens (Human) apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular senescence [GO:0090398]; chromatin remodeling [GO:0006338]; cloacal septation [GO:0060197]; cranial skeletal system development [GO:1904888]; ectoderm and mesoderm interaction [GO:0007499]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; epidermal cell division [GO:0010481]; epithelial cell development [GO:0002064]; establishment of planar polarity [GO:0001736]; establishment of skin barrier [GO:0061436]; female genitalia morphogenesis [GO:0048807]; hair follicle morphogenesis [GO:0031069]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; keratinocyte differentiation [GO:0030216]; keratinocyte proliferation [GO:0043616]; multicellular organism aging [GO:0010259]; negative regulation of cellular senescence [GO:2000773]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of keratinocyte differentiation [GO:0045617]; negative regulation of mesoderm development [GO:2000381]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron apoptotic process [GO:0051402]; Notch signaling pathway [GO:0007219]; odontogenesis of dentin-containing tooth [GO:0042475]; polarized epithelial cell differentiation [GO:0030859]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cell cycle G1/S phase transition [GO:1902808]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of fibroblast apoptotic process [GO:2000271]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of somatic stem cell population maintenance [GO:1904674]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; prostatic bud formation [GO:0060513]; protein tetramerization [GO:0051262]; proximal/distal pattern formation [GO:0009954]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of epidermal cell division [GO:0010482]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal system development [GO:0001501]; skin morphogenesis [GO:0043589]; spermatogenesis [GO:0007283]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; stem cell proliferation [GO:0072089]; sympathetic nervous system development [GO:0048485]; transcription by RNA polymerase II [GO:0006366] GO:0000122; GO:0000785; GO:0000977; GO:0000978; GO:0000981; GO:0001228; GO:0001501; GO:0001736; GO:0002039; GO:0002064; GO:0003677; GO:0003682; GO:0003684; GO:0003700; GO:0005634; GO:0005654; GO:0005737; GO:0005791; GO:0006338; GO:0006357; GO:0006366; GO:0006915; GO:0006974; GO:0007219; GO:0007283; GO:0007499; GO:0009954; GO:0010259; GO:0010481; GO:0010482; GO:0010838; GO:0030216; GO:0030425; GO:0030859; GO:0031069; GO:0032991; GO:0033147; GO:0035115; GO:0035116; GO:0036342; GO:0042475; GO:0042771; GO:0042802; GO:0043281; GO:0043589; GO:0043616; GO:0045617; GO:0045669; GO:0045747; GO:0045892; GO:0045893; GO:0045944; GO:0046872; GO:0048485; GO:0048807; GO:0050699; GO:0051262; GO:0051402; GO:0060197; GO:0060513; GO:0060529; GO:0061436; GO:0072089; GO:0090398; GO:0097371; GO:1902808; GO:1904674; GO:1904888; GO:2000271; GO:2000381; GO:2000648; GO:2000773; GO:2001235 8925 XM_044313829.1 36 1 22 29 54 NA NA NA NA NA NA 8926 XM_044327850.1 1929 3901 2317 3533 4005 NA NA NA NA NA NA 8927 XM_029331632.2 32 153 29 38 41 NA NA NA NA NA NA 8928 XM_044310641.1 6 0 5 6 32 NA NA NA NA NA NA 8929 XM_044328254.1 16 2 16 14 100 NA NA NA NA NA NA 8930 XM_044328880.1 14 0 3 0 0 Q6L8S8 6.81e-61 Beta-1,4-N-acetylgalactosaminyltransferase 3 (Beta4GalNAc-T3) (Beta4GalNAcT3) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase III) (N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 2) (NGalNAc-T2) Mus musculus (Mouse) chondroitin sulfate biosynthetic process [GO:0030206] GO:0005794; GO:0008376; GO:0030206; GO:0032580; GO:0033842; GO:0043231; GO:0047238 8931 XM_044323974.1 499 124 95 441 216 NA NA NA NA NA NA 8932 XR_006396550.1 0 17 6 4 8 Q8K2J9 1.62e-69 BTB/POZ domain-containing protein 6 Mus musculus (Mouse) neurogenesis [GO:0022008] GO:0005829; GO:0022008 8933 XM_029341582.2 34 78 45 83 20 NA NA NA NA NA NA 8934 XM_044317519.1 118 25 16 2 18 Q7RTR2 2.77e-36 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 8935 XM_029337334.2 65 15 36 37 75 O09113 1.04e-33 Homeobox protein orthopedia Mus musculus (Mouse) dopaminergic neuron differentiation [GO:0071542]; forebrain neuron differentiation [GO:0021879]; hypothalamus cell differentiation [GO:0021979]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuroblast proliferation [GO:0007405]; neuroendocrine cell differentiation [GO:0061101]; neurohypophysis development [GO:0021985]; neuron differentiation [GO:0030182]; positive regulation of neuroblast proliferation [GO:0002052] GO:0000122; GO:0000977; GO:0001227; GO:0001650; GO:0002052; GO:0003677; GO:0005654; GO:0007405; GO:0016604; GO:0021879; GO:0021979; GO:0021985; GO:0030182; GO:0061101; GO:0071542 8936 XM_029337229.2 1762 1026 676 1345 1365 Q86YT6 0 E3 ubiquitin-protein ligase MIB1 (EC 2.3.2.27) (DAPK-interacting protein 1) (DIP-1) (Mind bomb homolog 1) (RING-type E3 ubiquitin transferase MIB1) (Zinc finger ZZ type with ankyrin repeat domain protein 2) Homo sapiens (Human) blood vessel development [GO:0001568]; endocytosis [GO:0006897]; heart looping [GO:0001947]; in utero embryonic development [GO:0001701]; negative regulation of neuron differentiation [GO:0045665]; neural tube formation [GO:0001841]; neuron differentiation [GO:0030182]; Notch signaling pathway [GO:0007219]; positive regulation of endocytosis [GO:0045807]; protein ubiquitination [GO:0016567]; somitogenesis [GO:0001756]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0001568; GO:0001701; GO:0001756; GO:0001841; GO:0001947; GO:0004842; GO:0005737; GO:0005813; GO:0005829; GO:0005886; GO:0006511; GO:0006897; GO:0007219; GO:0008270; GO:0014069; GO:0016567; GO:0030182; GO:0031410; GO:0045665; GO:0045807 8937 XM_029329539.2 0 0 0 9 0 P30974 1.38e-30 Tachykinin-like peptides receptor 86C (NKD) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; inter-male aggressive behavior [GO:0002121]; neuropeptide signaling pathway [GO:0007218]; tachykinin receptor signaling pathway [GO:0007217] GO:0002121; GO:0004995; GO:0005886; GO:0007186; GO:0007217; GO:0007218; GO:0008188; GO:0016020 8938 XM_029351315.2 357 524 92 224 133 Q3T9E4 4.35e-46 T-cell-specific guanine nucleotide triphosphate-binding protein 2 (EC 3.6.5.-) (Interferon-gamma-inducible GTPase Ifggb6 protein) (T-cell-specific guanine nucleotide triphosphate-binding protein) Mus musculus (Mouse) cellular response to interferon-beta [GO:0035458]; defense response [GO:0006952]; innate immune response [GO:0045087] GO:0003924; GO:0005525; GO:0005789; GO:0005794; GO:0006952; GO:0035458; GO:0045087 8939 XM_029335874.2 9 114 0 0 0 A6QLE6 8.02e-177 Anoctamin-4 (Transmembrane protein 16D) Bos taurus (Bovine) chloride transmembrane transport [GO:1902476]; lipid transport [GO:0006869]; transmembrane transport [GO:0055085] GO:0005229; GO:0005254; GO:0005886; GO:0006869; GO:0046983; GO:0055085; GO:1902476 8940 XM_044308879.1 12 22 5 11 13 NA NA NA NA NA NA 8941 XM_029338037.2 0 18 9 35 14 NA NA NA NA NA NA 8942 XM_029344757.2 1802 1286 856 1195 1079 Q921M3 0 Splicing factor 3B subunit 3 (Pre-mRNA-splicing factor SF3b 130 kDa subunit) (SF3b130) (Spliceosome-associated protein 130) (SAP 130) Mus musculus (Mouse) histone H3 acetylation [GO:0043966]; monoubiquitinated histone deubiquitination [GO:0035521]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of protein catabolic process [GO:0042177]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA repair [GO:0006282]; regulation of RNA splicing [GO:0043484] GO:0000124; GO:0000398; GO:0005634; GO:0005654; GO:0005684; GO:0005686; GO:0005689; GO:0005730; GO:0006282; GO:0030620; GO:0035521; GO:0035522; GO:0042177; GO:0043484; GO:0043966; GO:0044877; GO:0045893; GO:0071005; GO:0071013 8943 XM_044320707.1 5 10 7 122 23 NA NA NA NA NA NA 8944 XM_029329587.2 270 114 108 140 279 Q5E9H5 3.37e-173 Mitochondrial chaperone BCS1 (BCS1-like protein) Bos taurus (Bovine) mitochondrial cytochrome c oxidase assembly [GO:0033617]; mitochondrial respiratory chain complex I assembly [GO:0032981]; mitochondrial respiratory chain complex III assembly [GO:0034551]; protein insertion into mitochondrial inner membrane from matrix [GO:0032979] GO:0005524; GO:0005743; GO:0016887; GO:0032979; GO:0032981; GO:0033617; GO:0034551 8945 XM_029341184.2 642 336 169 506 247 Q62717 0 Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1) (rCAPS) Rattus norvegicus (Rat) catecholamine secretion [GO:0050432]; establishment of localization in cell [GO:0051649]; exocytosis [GO:0006887]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of exocytosis [GO:0045921]; presynaptic dense core vesicle exocytosis [GO:0099525]; protein transport [GO:0015031]; regulated exocytosis [GO:0045055]; synaptic vesicle priming [GO:0016082]; vesicle organization [GO:0016050] GO:0005509; GO:0005546; GO:0006887; GO:0015031; GO:0016050; GO:0016082; GO:0019901; GO:0031045; GO:0031410; GO:0045055; GO:0045921; GO:0045956; GO:0050432; GO:0051649; GO:0098674; GO:0098793; GO:0098978; GO:0099525 8946 XM_029338202.2 9184 9795 4819 8584 6986 P21573 3.36e-46 Y-box-binding protein 1 (YB-1) (Y-box transcription factor) Xenopus laevis (African clawed frog) embryonic morphogenesis [GO:0048598]; epidermis development [GO:0008544]; miRNA transport [GO:1990428]; mRNA processing [GO:0006397]; mRNA stabilization [GO:0048255]; negative regulation of cellular senescence [GO:2000773]; negative regulation of translation [GO:0017148]; RNA splicing [GO:0008380]; RNA transport [GO:0050658]; tRNA transport [GO:0051031] GO:0003677; GO:0003723; GO:0005737; GO:0006397; GO:0008380; GO:0008544; GO:0017148; GO:0035198; GO:0048255; GO:0048598; GO:0050658; GO:0051031; GO:0062153; GO:0070062; GO:0071204; GO:1990428; GO:2000773 8947 XM_029329810.2 120 51 46 41 0 NA NA NA NA NA NA 8948 XM_029356129.2 0 0 2 9 42 Q9VCA2 8.98e-59 Organic cation transporter protein Drosophila melanogaster (Fruit fly) apoptotic process [GO:0006915]; ion transport [GO:0006811] GO:0006811; GO:0006915; GO:0016020; GO:0022857 8949 XM_029349564.2 0 23 14 1 74 Q4U4D2 2.17e-46 Melanopsin (Opsin-4) Podarcis siculus (Italian wall lizard) phototransduction [GO:0007602]; visual perception [GO:0007601] GO:0004930; GO:0005886; GO:0007601; GO:0007602; GO:0009881 8950 XR_003825387.2 594 38 20 233 134 NA NA NA NA NA NA 8951 XM_044323815.1 31 7 6 8 17 C3VPR6 2.72e-27 Protein NLRC5 Mus musculus (Mouse) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of type II interferon-mediated signaling pathway [GO:0060335]; regulation of kinase activity [GO:0043549]; response to bacterium [GO:0009617] GO:0000978; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0009617; GO:0032088; GO:0035556; GO:0043549; GO:0045087; GO:0045345; GO:0045944; GO:0051607; GO:0060335; GO:0060339; GO:0060340 8952 XM_029348724.2 0 0 0 197 141 NA NA NA NA NA NA 8953 XM_029334297.2 6 38 0 211 618 NA NA NA NA NA NA 8954 XM_044313755.1 10 0 0 0 9 NA NA NA NA NA NA 8955 XM_044315204.1 0 6 0 0 0 NA NA NA NA NA NA 8956 XM_029353288.2 0 0 0 0 57 Q8N9I5 1.38e-78 Fatty acid desaturase 6 (EC 1.14.19.-) Homo sapiens (Human) fatty acid biosynthetic process [GO:0006633]; lipid metabolic process [GO:0006629] GO:0006629; GO:0006633; GO:0016020; GO:0016717 8957 XR_006393709.1 7 272 431 12 499 NA NA NA NA NA NA 8958 XR_003823504.2 93 82 44 104 64 NA NA NA NA NA NA 8959 XM_029325249.2 113 87 32 68 54 NA NA NA NA NA NA 8960 XM_029329088.2 61 32 15 24 53 Q94K49 1e-36 Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1 (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) epigenetic regulation of gene expression [GO:0040029] GO:0003682; GO:0004518; GO:0005634; GO:0035098; GO:0035102; GO:0040029; GO:0046872 8961 XM_044323758.1 28 0 86 94 43 NA NA NA NA NA NA 8962 XM_044326264.1 7 0 8 67 140 NA NA NA NA NA NA 8963 XR_006393834.1 42 6 52 13 287 NA NA NA NA NA NA 8964 XM_029331891.2 468 243 309 319 509 Q9NZM4 1.29e-22 BRD4-interacting chromatin-remodeling complex-associated protein (Glioma tumor suppressor candidate region gene 1 protein) Homo sapiens (Human) chromatin remodeling [GO:0006338]; negative regulation of cell differentiation [GO:0045596]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of stem cell population maintenance [GO:1902459]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000785; GO:0005634; GO:0006338; GO:0006357; GO:0008284; GO:0016514; GO:0045596; GO:0045893; GO:0140288; GO:0140537; GO:1902459 8965 XM_044316899.1 20 6 13 7 50 NA NA NA NA NA NA 8966 XM_029352465.2 566 357 149 503 572 NA NA NA NA NA NA 8967 XR_003828624.2 28 25 6 41 39 NA NA NA NA NA NA 8968 XM_044314187.1 73 53 97 202 119 NA NA NA NA NA NA 8969 XM_044322264.1 217 298 289 479 499 NA NA NA NA NA NA 8970 XM_029349720.2 0 20 0 0 6 P11617 5.79e-24 Adenosine receptor A2a Canis lupus familiaris (Dog) (Canis familiaris) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; apoptotic signaling pathway [GO:0097190]; eating behavior [GO:0042755]; G protein-coupled adenosine receptor signaling pathway [GO:0001973]; G protein-coupled receptor signaling pathway [GO:0007186]; inhibitory postsynaptic potential [GO:0060080]; locomotory behavior [GO:0007626]; negative regulation of alpha-beta T cell activation [GO:0046636]; negative regulation of inflammatory response [GO:0050728]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; response to amphetamine [GO:0001975]; response to inorganic substance [GO:0010035]; response to purine-containing compound [GO:0014074]; synaptic transmission, dopaminergic [GO:0001963] GO:0001609; GO:0001963; GO:0001973; GO:0001975; GO:0004930; GO:0005886; GO:0007186; GO:0007189; GO:0007626; GO:0008289; GO:0010035; GO:0014074; GO:0019899; GO:0032230; GO:0042755; GO:0042802; GO:0046636; GO:0050728; GO:0060080; GO:0097190; GO:0098794; GO:2001235 8971 XM_044321841.1 176 93 130 138 129 O95260 4.01e-133 Arginyl-tRNA--protein transferase 1 (Arginyltransferase 1) (R-transferase 1) (EC 2.3.2.8) (Arginine-tRNA--protein transferase 1) Homo sapiens (Human) proteasomal protein catabolic process [GO:0010498]; protein arginylation [GO:0016598] GO:0004057; GO:0005634; GO:0005737; GO:0010498; GO:0016598 8972 XM_029356576.2 1784 1232 1090 1675 1616 Q2V2M9 1.41e-152 FH1/FH2 domain-containing protein 3 (Formactin-2) (Formin homolog overexpressed in spleen 2) (hFHOS2) Homo sapiens (Human) cardiac myofibril assembly [GO:0055003]; cortical actin cytoskeleton organization [GO:0030866]; negative regulation of actin filament polymerization [GO:0030837]; sarcomere organization [GO:0045214] GO:0005737; GO:0005856; GO:0030018; GO:0030837; GO:0030866; GO:0045214; GO:0051015; GO:0055003 8973 XM_029356576.2 1784 1232 1090 1675 1616 Q2V2M9 4.02e-132 FH1/FH2 domain-containing protein 3 (Formactin-2) (Formin homolog overexpressed in spleen 2) (hFHOS2) Homo sapiens (Human) cardiac myofibril assembly [GO:0055003]; cortical actin cytoskeleton organization [GO:0030866]; negative regulation of actin filament polymerization [GO:0030837]; sarcomere organization [GO:0045214] GO:0005737; GO:0005856; GO:0030018; GO:0030837; GO:0030866; GO:0045214; GO:0051015; GO:0055003 8974 XM_029342542.2 0 59 0 47 75 Q9EQD2 1.62e-33 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 8975 XM_044328237.1 28 50 4 21 46 O60290 4.36e-81 Zinc finger protein 862 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006355; GO:0046872; GO:0046983 8976 XM_029344933.2 323 331 277 629 357 NA NA NA NA NA NA 8977 XM_029334092.2 0 9 0 7 5 NA NA NA NA NA NA 8978 XM_044320823.1 7 0 18 0 18 NA NA NA NA NA NA 8979 XM_029348413.2 373 212 109 189 280 Q9JLY0 1.47e-24 Suppressor of cytokine signaling 6 (SOCS-6) (Cytokine-inducible SH2 protein 4) (CIS-4) (Suppressor of cytokine signaling 4) (SOCS-4) Mus musculus (Mouse) intracellular signal transduction [GO:0035556]; negative regulation of signal transduction [GO:0009968]; negative regulation of T cell activation [GO:0050868]; phosphatidylinositol phosphate biosynthetic process [GO:0046854]; proteasomal protein catabolic process [GO:0010498]; protein ubiquitination [GO:0016567]; regulation of growth [GO:0040008] GO:0001772; GO:0005829; GO:0005942; GO:0009968; GO:0010498; GO:0016567; GO:0035556; GO:0040008; GO:0046854; GO:0046935; GO:0050868 8980 XR_006393736.1 5 31 0 38 0 NA NA NA NA NA NA 8981 XM_044308876.1 507 108 94 100 309 D3ZS74 6.44e-71 Metalloendopeptidase OMA1, mitochondrial (EC 3.4.24.-) (Overlapping with the m-AAA protease 1 homolog) Rattus norvegicus (Rat) cristae formation [GO:0042407]; diet induced thermogenesis [GO:0002024]; energy homeostasis [GO:0097009]; glucose metabolic process [GO:0006006]; HRI-mediated signaling [GO:0140468]; integrated stress response signaling [GO:0140467]; lipid metabolic process [GO:0006629]; mitochondrial protein processing [GO:0034982]; mitochondrial respiratory chain complex assembly [GO:0033108]; mitochondrion organization [GO:0007005]; negative regulation of mitochondrial fusion [GO:0010637]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cold-induced thermogenesis [GO:0120162]; protein autoprocessing [GO:0016540]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of cristae formation [GO:1903850]; zymogen activation [GO:0031638] GO:0002024; GO:0004222; GO:0005739; GO:0005743; GO:0006006; GO:0006515; GO:0006629; GO:0007005; GO:0008289; GO:0010637; GO:0016020; GO:0016540; GO:0031638; GO:0031966; GO:0033108; GO:0034982; GO:0042407; GO:0043065; GO:0046872; GO:0051603; GO:0097009; GO:0120162; GO:0140467; GO:0140468; GO:1903850 8982 XR_006393970.1 9 0 1 5 16 NA NA NA NA NA NA 8983 XM_044327815.1 0 0 51 0 93 NA NA NA NA NA NA 8984 XM_044315459.1 33 144 53 52 90 NA NA NA NA NA NA 8985 XM_029343665.2 123 106 117 156 155 NA NA NA NA NA NA 8986 XM_044312162.1 0 0 29 5 6 NA NA NA NA NA NA 8987 XM_044318175.1 314 111 153 89 176 Q8R0V5 2.34e-102 Indoleamine 2,3-dioxygenase 2 (IDO-2) (EC 1.13.11.-) (Indoleamine 2,3-dioxygenase-like protein 1) (Indoleamine-pyrrole 2,3-dioxygenase-like protein 1) Mus musculus (Mouse) 'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; immune system process [GO:0002376]; tryptophan catabolic process to kynurenine [GO:0019441] GO:0002376; GO:0004833; GO:0005737; GO:0019441; GO:0020037; GO:0033754; GO:0034354; GO:0046872 8988 XR_006393764.1 2 7 2 9 4 NA NA NA NA NA NA 8989 XR_006394703.1 23 0 6 5 58 NA NA NA NA NA NA 8990 XM_044325498.1 61 62 88 166 63 P07911 1.72e-32 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Homo sapiens (Human) antibacterial innate immune response [GO:0140367]; apoptotic signaling pathway [GO:0097190]; autophagy [GO:0006914]; cellular calcium ion homeostasis [GO:0006874]; cellular chloride ion homeostasis [GO:0030644]; cellular defense response [GO:0006968]; cellular phosphate ion homeostasis [GO:0030643]; cellular response to unfolded protein [GO:0034620]; cellular sodium ion homeostasis [GO:0006883]; chaperone-mediated protein folding [GO:0061077]; citric acid secretion [GO:0046720]; collecting duct development [GO:0072044]; connective tissue replacement [GO:0097709]; creatinine homeostasis [GO:0097273]; defense response to Gram-negative bacterium [GO:0050829]; endoplasmic reticulum organization [GO:0007029]; glomerular filtration [GO:0003094]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; juxtaglomerular apparatus development [GO:0072051]; leukocyte cell-cell adhesion [GO:0007159]; lipid metabolic process [GO:0006629]; metanephric ascending thin limb development [GO:0072218]; metanephric distal convoluted tubule development [GO:0072221]; metanephric thick ascending limb development [GO:0072233]; micturition [GO:0060073]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell population proliferation [GO:0008285]; neutrophil migration [GO:1990266]; organ or tissue specific immune response [GO:0002251]; peptidyl-threonine phosphorylation [GO:0018107]; potassium ion homeostasis [GO:0055075]; protein localization to vacuole [GO:0072665]; protein transport into plasma membrane raft [GO:0044861]; regulation of blood pressure [GO:0008217]; regulation of protein transport [GO:0051223]; regulation of urine volume [GO:0035809]; renal sodium ion absorption [GO:0070294]; renal urate salt excretion [GO:0097744]; renal water homeostasis [GO:0003091]; response to lipopolysaccharide [GO:0032496]; response to water deprivation [GO:0009414]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; ubiquitin-dependent ERAD pathway [GO:0030433]; urate transport [GO:0015747]; urea transmembrane transport [GO:0071918] GO:0000922; GO:0002251; GO:0003091; GO:0003094; GO:0005201; GO:0005509; GO:0005615; GO:0005783; GO:0005796; GO:0005929; GO:0006629; GO:0006874; GO:0006883; GO:0006914; GO:0006954; GO:0006968; GO:0007029; GO:0007157; GO:0007159; GO:0008217; GO:0008285; GO:0008380; GO:0009410; GO:0009414; GO:0009986; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0018107; GO:0019864; GO:0019898; GO:0030433; GO:0030643; GO:0030644; GO:0032496; GO:0033209; GO:0033555; GO:0034620; GO:0035809; GO:0044861; GO:0046720; GO:0050829; GO:0051223; GO:0055075; GO:0060073; GO:0060170; GO:0061077; GO:0070062; GO:0070294; GO:0071918; GO:0072044; GO:0072051; GO:0072218; GO:0072221; GO:0072233; GO:0072665; GO:0097190; GO:0097273; GO:0097709; GO:0097744; GO:0140367; GO:1990266 8991 XR_006391459.1 0 24 24 0 0 NA NA NA NA NA NA 8992 XM_029343530.2 10 0 12 1 16 NA NA NA NA NA NA 8993 XR_006396268.1 0 3 20 7 105 NA NA NA NA NA NA 8994 XM_044322317.1 396 227 334 330 273 NA NA NA NA NA NA 8995 XR_006397995.1 102 124 65 138 232 NA NA NA NA NA NA 8996 XM_029349713.2 25 6 42 41 17 P97363 2.46e-171 Serine palmitoyltransferase 2 (EC 2.3.1.50) (Long chain base biosynthesis protein 2) (LCB 2) (Long chain base biosynthesis protein 2a) (LCB2a) (Serine-palmitoyl-CoA transferase 2) (SPT 2) Mus musculus (Mouse) adipose tissue development [GO:0060612]; ceramide biosynthetic process [GO:0046513]; lipophagy [GO:0061724]; positive regulation of lipophagy [GO:1904504]; sphinganine biosynthetic process [GO:0046511]; sphingolipid biosynthetic process [GO:0030148]; sphingomyelin biosynthetic process [GO:0006686]; sphingosine biosynthetic process [GO:0046512] GO:0004758; GO:0005739; GO:0005789; GO:0006686; GO:0017059; GO:0030148; GO:0030170; GO:0046511; GO:0046512; GO:0046513; GO:0060612; GO:0061724; GO:1904504 8997 XM_044328111.1 572 556 440 614 329 NA NA NA NA NA NA 8998 XR_006396968.1 150 21 5 101 43 NA NA NA NA NA NA 8999 XM_044327401.1 185 120 96 143 178 Q3UZV7 3.05e-33 Endosome/lysosome-associated apoptosis and autophagy regulator family member 2 (Estrogen-induced gene 121-like protein) Mus musculus (Mouse) negative regulation of nervous system development [GO:0051961]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of epidermis development [GO:0045684] GO:0005886; GO:0016020; GO:0030513; GO:0045684; GO:0051961; GO:0070700 9000 XR_006391677.1 8 137 4 40 41 NA NA NA NA NA NA 9001 XR_006395966.1 1 0 0 8 1 P0C0R5 1.03e-24 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) Rattus norvegicus (Rat) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006623; GO:0010506; GO:0015630; GO:0016236; GO:0016241; GO:0030242; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 9002 XM_044325752.1 6 9 0 96 227 NA NA NA NA NA NA 9003 XM_044313280.1 797 1162 733 765 1056 Q6P3N9 5.68e-120 Zinc transporter 7 (ZnT-7) (Solute carrier family 30 member 7) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cellular zinc ion homeostasis [GO:0006882] GO:0005385; GO:0005794; GO:0006882; GO:0016020 9004 XM_029358263.2 207 200 169 272 233 NA NA NA NA NA NA 9005 XM_029331335.2 417 128 114 390 208 Q9YH18 2.64e-66 KH domain-containing RNA-binding protein QKI (Protein quaking) Gallus gallus (Chicken) long-chain fatty acid biosynthetic process [GO:0042759]; mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; myelination [GO:0042552]; positive regulation of gene expression [GO:0010628]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of translation [GO:0006417]; RNA splicing [GO:0008380]; spermatid development [GO:0007286]; vascular associated smooth muscle cell differentiation [GO:0035886]; vasculogenesis [GO:0001570] GO:0001570; GO:0003729; GO:0005634; GO:0005737; GO:0006397; GO:0006417; GO:0007286; GO:0008380; GO:0010628; GO:0017124; GO:0035886; GO:0042552; GO:0042759; GO:0045202; GO:0048024; GO:0051028 9006 XM_044321426.1 0 0 14 0 2 NA NA NA NA NA NA 9007 XR_006396332.1 33 0 4 0 85 NA NA NA NA NA NA 9008 XR_006397389.1 45 31 80 94 375 NA NA NA NA NA NA 9009 XM_029357647.2 17 24 29 35 33 P48733 2.56e-28 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Bos taurus (Bovine) antibacterial innate immune response [GO:0140367]; defense response to Gram-negative bacterium [GO:0050829] GO:0000922; GO:0005201; GO:0005509; GO:0005576; GO:0005929; GO:0016020; GO:0016323; GO:0016324; GO:0031012; GO:0050829; GO:0060170; GO:0140367 9010 XM_044313953.1 0 19 9 0 0 NA NA NA NA NA NA 9011 XM_044323275.1 1897 2306 1248 2269 2372 NA NA NA NA NA NA 9012 XM_029328448.2 886 1048 333 557 444 Q63665 1.9e-61 Upstream stimulatory factor 2 (Major late transcription factor 2) (Upstream transcription factor 2) Rattus norvegicus (Rat) lactation [GO:0007595]; lipid homeostasis [GO:0055088]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter by glucose [GO:0000432]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000432; GO:0000978; GO:0000981; GO:0003677; GO:0003690; GO:0003700; GO:0005634; GO:0006357; GO:0007595; GO:0042802; GO:0042803; GO:0043425; GO:0043565; GO:0044877; GO:0045893; GO:0045944; GO:0046982; GO:0055088; GO:1990837 9013 XM_044329065.1 13 18 3 4 148 NA NA NA NA NA NA 9014 XM_029329177.2 55 32 24 30 60 NA NA NA NA NA NA 9015 XM_029326516.2 2 11 1 11 29 NA NA NA NA NA NA 9016 XM_029332890.2 135 78 71 132 96 Q8K2J9 8.25e-80 BTB/POZ domain-containing protein 6 Mus musculus (Mouse) neurogenesis [GO:0022008] GO:0005829; GO:0022008 9017 XM_029351989.2 230 6 84 93 23 NA NA NA NA NA NA 9018 XM_029328897.2 143 112 80 96 326 NA NA NA NA NA NA 9019 XM_029328669.2 761 582 330 396 446 NA NA NA NA NA NA 9020 XR_003823719.2 0 0 18 0 6 NA NA NA NA NA NA 9021 XM_029332689.2 505 170 249 415 279 A4IHF8 1.39e-73 Protein DPCD Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA NA 9022 XM_044326768.1 56 64 62 29 156 P0CT39 1.56e-62 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 9023 XM_044323146.1 105 94 73 243 19 NA NA NA NA NA NA 9024 XM_029329014.2 338 274 435 488 457 Q9BUJ2 9.45e-130 Heterogeneous nuclear ribonucleoprotein U-like protein 1 (Adenovirus early region 1B-associated protein 5) (E1B-55 kDa-associated protein 5) (E1B-AP5) Homo sapiens (Human) response to virus [GO:0009615]; RNA processing [GO:0006396] GO:0003723; GO:0005634; GO:0005654; GO:0006396; GO:0009615; GO:0019899; GO:0045202; GO:1990904 9025 XM_029356289.2 0 0 1 0 653 NA NA NA NA NA NA 9026 XM_044309523.1 0 0 0 263 24 O55058 4.3e-35 EGF-containing fibulin-like extracellular matrix protein 2 (Fibulin-4) (FIBL-4) (Protein H411) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) aorta development [GO:0035904]; aorta smooth muscle tissue morphogenesis [GO:0060414]; elastic fiber assembly [GO:0048251]; negative regulation of vascular associated smooth muscle cell proliferation [GO:1904706]; positive regulation of aortic smooth muscle cell differentiation [GO:1904831]; positive regulation of collagen fibril organization [GO:1904028]; positive regulation of smooth muscle cell-matrix adhesion [GO:1905609]; regulation of collagen fibril organization [GO:1904026]; vascular associated smooth muscle cell development [GO:0097084] GO:0001527; GO:0005509; GO:0005576; GO:0005604; GO:0008201; GO:0031012; GO:0035904; GO:0042803; GO:0048251; GO:0060414; GO:0071953; GO:0097084; GO:1904026; GO:1904028; GO:1904706; GO:1904831; GO:1905609 9027 XM_044309523.1 0 0 0 263 24 O55058 4.72e-27 EGF-containing fibulin-like extracellular matrix protein 2 (Fibulin-4) (FIBL-4) (Protein H411) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) aorta development [GO:0035904]; aorta smooth muscle tissue morphogenesis [GO:0060414]; elastic fiber assembly [GO:0048251]; negative regulation of vascular associated smooth muscle cell proliferation [GO:1904706]; positive regulation of aortic smooth muscle cell differentiation [GO:1904831]; positive regulation of collagen fibril organization [GO:1904028]; positive regulation of smooth muscle cell-matrix adhesion [GO:1905609]; regulation of collagen fibril organization [GO:1904026]; vascular associated smooth muscle cell development [GO:0097084] GO:0001527; GO:0005509; GO:0005576; GO:0005604; GO:0008201; GO:0031012; GO:0035904; GO:0042803; GO:0048251; GO:0060414; GO:0071953; GO:0097084; GO:1904026; GO:1904028; GO:1904706; GO:1904831; GO:1905609 9028 XM_029331908.2 130 124 56 19 37 Q9BQS2 6.49e-55 Synaptotagmin-15 (Chr10Syt) (Synaptotagmin XV) (SytXV) Homo sapiens (Human) calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; vesicle-mediated transport [GO:0016192] GO:0000149; GO:0001786; GO:0005509; GO:0005544; GO:0005886; GO:0014059; GO:0016192; GO:0017156; GO:0017158; GO:0030276; GO:0070382; GO:0071277 9029 XM_044319522.1 147 13 47 260 126 NA NA NA NA NA NA 9030 XM_029351624.2 1350 614 454 766 650 Q96H20 6.51e-103 Vacuolar-sorting protein SNF8 (ELL-associated protein of 30 kDa) (ESCRT-II complex subunit VPS22) (hVps22) Homo sapiens (Human) early endosome to late endosome transport [GO:0045022]; endocytic recycling [GO:0032456]; localization [GO:0051179]; macroautophagy [GO:0016236]; membrane fission [GO:0090148]; multivesicular body assembly [GO:0036258]; multivesicular body sorting pathway [GO:0071985]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of gene expression [GO:0010628]; positive regulation of protein catabolic process [GO:0045732]; protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]; regulation of protein catabolic process [GO:0042176]; regulation of protein complex stability [GO:0061635]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of viral budding via host ESCRT complex [GO:1903772] GO:0000814; GO:0005634; GO:0005654; GO:0005667; GO:0005737; GO:0005829; GO:0005886; GO:0006357; GO:0008022; GO:0008289; GO:0010008; GO:0010628; GO:0016020; GO:0016236; GO:0016247; GO:0031902; GO:0032456; GO:0036258; GO:0042176; GO:0042803; GO:0043328; GO:0045022; GO:0045732; GO:0047485; GO:0048471; GO:0051179; GO:0055037; GO:0061635; GO:0070062; GO:0071985; GO:0090148; GO:1903543; GO:1903772 9031 XM_044321490.1 129 173 134 165 245 Q9C8G5 2.54e-53 CSC1-like protein ERD4 (Hyperosmolality-gated Ca2+ permeable channel 3.1) (AtOSCA3.1) (Protein EARLY-RESPONSIVE TO DEHYDRATION STRESS 4) Arabidopsis thaliana (Mouse-ear cress) NA GO:0000325; GO:0003729; GO:0005227; GO:0005634; GO:0005886; GO:0009506; GO:0009941 9032 XM_044320222.1 116 66 56 63 108 NA NA NA NA NA NA 9033 XR_006393093.1 81 8 15 2 51 NA NA NA NA NA NA 9034 XM_029336000.2 0 45 0 0 0 O75762 1.43e-99 Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation-sensitive protein p120) (p120) (Wasabi receptor) Homo sapiens (Human) calcium ion transmembrane transport [GO:0070588]; cell surface receptor signaling pathway [GO:0007166]; cellular calcium ion homeostasis [GO:0006874]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to organic substance [GO:0071310]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; ion transport [GO:0006811]; protein homotetramerization [GO:0051289]; response to cold [GO:0009409]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; sensory perception of pain [GO:0019233]; thermoception [GO:0050955] GO:0005262; GO:0005886; GO:0006811; GO:0006874; GO:0007166; GO:0009409; GO:0009410; GO:0010033; GO:0014070; GO:0015267; GO:0015278; GO:0019233; GO:0032421; GO:0042802; GO:0048265; GO:0050955; GO:0050966; GO:0050968; GO:0051289; GO:0070301; GO:0070588; GO:0071310; GO:0097604 9035 XM_029334636.2 0 0 144 37 162 Q60HE9 0 Lysosomal alpha-mannosidase (Laman) (EC 3.2.1.24) (Lysosomal acid alpha-mannosidase) (Mannosidase alpha class 2B member 1) (Mannosidase alpha-B) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) mannose metabolic process [GO:0006013] GO:0004559; GO:0005764; GO:0006013; GO:0030246; GO:0046872 9036 XM_044312360.1 55 0 0 41 198 Q27245 9.22e-134 Putative aminopeptidase W07G4.4 (EC 3.4.11.-) Caenorhabditis elegans proteolysis [GO:0006508] GO:0005737; GO:0006508; GO:0008233; GO:0030145; GO:0070006 9037 XR_003828265.2 18 11 0 12 12 NA NA NA NA NA NA 9038 XM_029344253.2 258 878 224 199 214 NA NA NA NA NA NA 9039 XM_029346975.2 512 342 481 839 701 Q15582 1.52e-51 Transforming growth factor-beta-induced protein ig-h3 (Beta ig-h3) (Kerato-epithelin) (RGD-containing collagen-associated protein) (RGD-CAP) Homo sapiens (Human) angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; cell population proliferation [GO:0008283]; chondrocyte differentiation [GO:0002062]; extracellular matrix organization [GO:0030198]; localization [GO:0051179]; negative regulation of cell adhesion [GO:0007162]; response to stimulus [GO:0050896]; visual perception [GO:0007601] GO:0001525; GO:0002062; GO:0005178; GO:0005201; GO:0005518; GO:0005576; GO:0005604; GO:0005615; GO:0005802; GO:0005886; GO:0007155; GO:0007162; GO:0007601; GO:0008283; GO:0030198; GO:0031012; GO:0042802; GO:0050839; GO:0050840; GO:0050896; GO:0051179; GO:0062023; GO:0070062 9040 XM_044326399.1 633 0 374 403 803 Q9Z2V9 3.26e-38 Cyclin-I Mus musculus (Mouse) mitotic cell cycle phase transition [GO:0044772]; regulation of cell cycle [GO:0051726]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079] GO:0000079; GO:0000307; GO:0005634; GO:0005737; GO:0016538; GO:0044772; GO:0051726 9041 XM_044322599.1 0 7 0 1 10 O43854 1.8e-24 EGF-like repeat and discoidin I-like domain-containing protein 3 (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1) Homo sapiens (Human) cell adhesion [GO:0007155]; positive regulation of cell-substrate adhesion [GO:0010811] GO:0005178; GO:0005509; GO:0007155; GO:0010811; GO:0062023; GO:0070062; GO:1903561 9042 XM_044322599.1 0 7 0 1 10 O43854 3.52e-23 EGF-like repeat and discoidin I-like domain-containing protein 3 (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1) Homo sapiens (Human) cell adhesion [GO:0007155]; positive regulation of cell-substrate adhesion [GO:0010811] GO:0005178; GO:0005509; GO:0007155; GO:0010811; GO:0062023; GO:0070062; GO:1903561 9043 XM_029338279.2 237 171 137 395 118 Q62763 0 Casein kinase I isoform gamma-3 (CKI-gamma 3) (EC 2.7.11.1) Rattus norvegicus (Rat) endocytosis [GO:0006897]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055] GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005886; GO:0006468; GO:0006897; GO:0007165; GO:0016055; GO:0018105; GO:0046777; GO:0090263; GO:0106310 9044 XM_029342103.2 587 562 330 502 490 O45870 3.59e-63 Putative neutral sphingomyelinase (EC 3.1.4.12) Caenorhabditis elegans ceramide biosynthetic process [GO:0046513]; sphingolipid catabolic process [GO:0030149]; sphingomyelin metabolic process [GO:0006684] GO:0004620; GO:0004767; GO:0005783; GO:0005901; GO:0006684; GO:0016020; GO:0030149; GO:0046513; GO:0046872; GO:0071944 9045 XR_006396653.1 17 0 56 2 156 NA NA NA NA NA NA 9046 XM_029342458.2 5 17 26 17 2 NA NA NA NA NA NA 9047 XM_044327800.1 11 0 0 0 0 B8VIU6 6.3e-60 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 9048 XM_029339573.2 901 457 835 922 1147 NA NA NA NA NA NA 9049 XR_006391393.1 559 380 283 376 468 NA NA NA NA NA NA 9050 XM_029339335.2 451 351 230 305 331 Q6PG95 6.74e-55 Protein cramped-like (Cramped chromatin regulator homolog 1) (Hematological and neurological expressed 1-like protein) Mus musculus (Mouse) pattern specification process [GO:0007389] GO:0003677; GO:0003682; GO:0005634; GO:0007389 9051 XM_029341000.2 1028 700 570 526 577 Q3B8H0 2.64e-34 Transmembrane protein 107 Xenopus laevis (African clawed frog) cell projection organization [GO:0030030] GO:0016020; GO:0030030 9052 XM_044327913.1 1321 862 842 1247 1495 Q7Z6E9 1.52e-80 E3 ubiquitin-protein ligase RBBP6 (EC 2.3.2.27) (Proliferation potential-related protein) (Protein P2P-R) (RING-type E3 ubiquitin transferase RBBP6) (Retinoblastoma-binding Q protein 1) (RBQ-1) (Retinoblastoma-binding protein 6) (p53-associated cellular protein of testis) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; embryonic organ development [GO:0048568]; in utero embryonic development [GO:0001701]; mRNA processing [GO:0006397]; multicellular organism growth [GO:0035264]; protein ubiquitination [GO:0016567]; regulation of DNA replication [GO:0006275]; somite development [GO:0061053]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0001701; GO:0003723; GO:0004842; GO:0005634; GO:0005694; GO:0005730; GO:0005815; GO:0005829; GO:0006260; GO:0006275; GO:0006397; GO:0006511; GO:0006974; GO:0008270; GO:0016567; GO:0016607; GO:0019901; GO:0032991; GO:0035264; GO:0048568; GO:0061053; GO:0061630 9053 XM_029330033.2 8 0 3 0 12 NA NA NA NA NA NA 9054 XR_006391740.1 56 52 31 36 0 NA NA NA NA NA NA 9055 XM_029345773.2 1100 1118 666 1036 755 Q9UHD2 2.47e-143 Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1) Homo sapiens (Human) activation of innate immune response [GO:0002218]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; dendritic cell proliferation [GO:0044565]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of gene expression [GO:0010629]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of macroautophagy [GO:0016239]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of xenophagy [GO:1904417]; protein phosphorylation [GO:0006468]; regulation of neuron death [GO:1901214]; regulation of type I interferon production [GO:0032479]; response to virus [GO:0009615]; type I interferon-mediated signaling pathway [GO:0060337] GO:0002218; GO:0003676; GO:0004672; GO:0004674; GO:0005524; GO:0005654; GO:0005737; GO:0005829; GO:0006468; GO:0006954; GO:0007249; GO:0009615; GO:0010629; GO:0016239; GO:0018105; GO:0018107; GO:0019903; GO:0032479; GO:0032481; GO:0032727; GO:0032728; GO:0033138; GO:0042802; GO:0043123; GO:0043231; GO:0044565; GO:0045087; GO:0045944; GO:0050830; GO:0051219; GO:0051607; GO:0060337; GO:0060340; GO:0106310; GO:1901214; GO:1902554; GO:1904417 9056 XM_029334415.2 533 69 236 84 632 Q9XSC3 0 WD repeat-containing protein 44 (Rab11-binding protein) (Rabphilin-11) Bos taurus (Bovine) NA GO:0005794; GO:0005829; GO:0010008; GO:0048471 9057 XM_044325098.1 15 0 1 0 8 NA NA NA NA NA NA 9058 XM_044312589.1 83 10 41 69 77 Q4R7T7 1.03e-177 Tubulin delta chain (Delta-tubulin) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) cell projection organization [GO:0030030]; microtubule-based process [GO:0007017]; positive regulation of smoothened signaling pathway [GO:0045880] GO:0005200; GO:0005525; GO:0005634; GO:0005737; GO:0005814; GO:0005874; GO:0005929; GO:0007017; GO:0030030; GO:0045880 9059 XM_044311383.1 2 0 14 13 0 Q95LR0 1.6e-56 Cilia- and flagella-associated protein 91 (CFAP91) (AMY-1-associating protein expressed in testis 1) (AAT-1) (MYCBP/AMY-1-associated testis-expressed protein 1) (Protein MAATS1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) axonemal central apparatus assembly [GO:1904158]; cell differentiation [GO:0030154]; cilium movement [GO:0003341]; spermatogenesis [GO:0007283] GO:0003341; GO:0005739; GO:0005930; GO:0007283; GO:0030154; GO:0031514; GO:1904158 9060 XM_044311383.1 2 0 14 13 0 Q95LR0 1.6e-56 Cilia- and flagella-associated protein 91 (CFAP91) (AMY-1-associating protein expressed in testis 1) (AAT-1) (MYCBP/AMY-1-associated testis-expressed protein 1) (Protein MAATS1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) axonemal central apparatus assembly [GO:1904158]; cell differentiation [GO:0030154]; cilium movement [GO:0003341]; spermatogenesis [GO:0007283] GO:0003341; GO:0005739; GO:0005930; GO:0007283; GO:0030154; GO:0031514; GO:1904158 9061 XM_029337059.2 62 177 345 223 667 Q8IVH2 2.49e-75 Forkhead box protein P4 (Fork head-related protein-like A) Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000785; GO:0000978; GO:0000981; GO:0001227; GO:0005634; GO:0006357; GO:0046872 9062 XM_044309678.1 84 12 34 108 276 NA NA NA NA NA NA 9063 XM_029357254.2 0 0 11 0 5 Q62407 3.58e-43 Striated muscle-specific serine/threonine-protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1) Mus musculus (Mouse) cardiac muscle cell development [GO:0055013]; circulatory system development [GO:0072359]; in utero embryonic development [GO:0001701]; muscle cell differentiation [GO:0042692]; protein phosphorylation [GO:0006468]; respiratory system development [GO:0060541] GO:0001701; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0006468; GO:0042692; GO:0055013; GO:0060541; GO:0072359; GO:0106310 9064 XM_029357254.2 0 0 11 0 5 Q62407 1.11e-27 Striated muscle-specific serine/threonine-protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1) Mus musculus (Mouse) cardiac muscle cell development [GO:0055013]; circulatory system development [GO:0072359]; in utero embryonic development [GO:0001701]; muscle cell differentiation [GO:0042692]; protein phosphorylation [GO:0006468]; respiratory system development [GO:0060541] GO:0001701; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0006468; GO:0042692; GO:0055013; GO:0060541; GO:0072359; GO:0106310 9065 XM_029329317.2 394 426 310 606 804 M0R2J8 0 Doublecortin domain-containing protein 1 (Doublecortin domain-containing 5 protein) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; intracellular signal transduction [GO:0035556]; regulation of mitotic cytokinesis [GO:1902412] GO:0005737; GO:0005874; GO:0007049; GO:0008017; GO:0030246; GO:0030496; GO:0035556; GO:0051301; GO:0072686; GO:0090543; GO:1902412 9066 XM_029329317.2 394 426 310 606 804 M0R2J8 1.29e-25 Doublecortin domain-containing protein 1 (Doublecortin domain-containing 5 protein) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; intracellular signal transduction [GO:0035556]; regulation of mitotic cytokinesis [GO:1902412] GO:0005737; GO:0005874; GO:0007049; GO:0008017; GO:0030246; GO:0030496; GO:0035556; GO:0051301; GO:0072686; GO:0090543; GO:1902412 9067 XM_029356338.2 221 93 14 0 0 P0CF65 2.39e-101 Protein cereblon Gallus gallus (Chicken) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567] GO:0005634; GO:0005737; GO:0016567; GO:0031464; GO:0043161; GO:0046872 9068 XM_044326414.1 3 6 11 9 26 NA NA NA NA NA NA 9069 XM_044319404.1 33 22 27 22 55 NA NA NA NA NA NA 9070 XM_029342690.2 23 2 1 14 6 NA NA NA NA NA NA 9071 XM_044310151.1 35 0 10 3 0 NA NA NA NA NA NA 9072 XM_029323801.2 57 65 0 160 66 Q7T2C4 1.15e-126 NA NA NA NA 9073 XM_029341145.2 2530 5222 2639 7413 5884 A4GTP4 7.99e-22 ETS domain-containing protein Elk-1 Rattus norvegicus (Rat) cell differentiation [GO:0030154]; cellular response to gamma radiation [GO:0071480]; cellular response to lipid [GO:0071396]; cellular response to testosterone stimulus [GO:0071394]; DNA-templated transcription [GO:0006351]; DNA-templated transcription elongation [GO:0006354]; gene expression [GO:0010467]; liver development [GO:0001889]; lung development [GO:0030324]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of neuron death [GO:1901216]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; response to fibroblast growth factor [GO:0071774]; response to light stimulus [GO:0009416] GO:0000976; GO:0000978; GO:0000981; GO:0001228; GO:0001889; GO:0003682; GO:0003690; GO:0003700; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0006351; GO:0006354; GO:0006355; GO:0006357; GO:0009416; GO:0010467; GO:0030154; GO:0030324; GO:0030374; GO:0030425; GO:0043025; GO:0043679; GO:0045893; GO:0045944; GO:0061629; GO:0071394; GO:0071396; GO:0071480; GO:0071774; GO:1901216; GO:1990837 9074 XM_044316181.1 169 73 40 95 106 Q13395 1.85e-36 Probable methyltransferase TARBP1 (EC 2.1.1.-) (TAR RNA-binding protein 1) (TAR RNA-binding protein of 185 kDa) (TRP-185) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357]; tRNA methylation [GO:0030488] GO:0003723; GO:0005634; GO:0006357; GO:0016423; GO:0030488 9075 XM_044316181.1 169 73 40 95 106 Q13395 2.92e-35 Probable methyltransferase TARBP1 (EC 2.1.1.-) (TAR RNA-binding protein 1) (TAR RNA-binding protein of 185 kDa) (TRP-185) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357]; tRNA methylation [GO:0030488] GO:0003723; GO:0005634; GO:0006357; GO:0016423; GO:0030488 9076 XM_029340323.2 114 12 69 99 167 NA NA NA NA NA NA 9077 XR_003824060.2 320 290 249 522 476 NA NA NA NA NA NA 9078 XM_044314871.1 279 140 119 315 318 Q5JPE7 0 BOS complex subunit NOMO2 (Nodal modulator 2) (pM5 protein 2) Homo sapiens (Human) NA GO:0005789; GO:0030246; GO:0032991; GO:0043022 9079 XR_006391582.1 0 80 0 379 0 NA NA NA NA NA NA 9080 XM_029339707.2 2502 3138 2523 1870 2082 Q5R4W3 9.5e-40 DNA polymerase epsilon subunit 3 (DNA polymerase II subunit 3) (DNA polymerase epsilon subunit p17) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) DNA-templated DNA replication [GO:0006261]; histone H3 acetylation [GO:0043966]; nucleosome assembly [GO:0006334]; regulation of DNA replication [GO:0006275] GO:0003677; GO:0006261; GO:0006275; GO:0006334; GO:0008622; GO:0043966; GO:0046982; GO:0140672 9081 XM_044315574.1 36 35 26 27 34 NA NA NA NA NA NA 9082 XR_006396425.1 7 0 0 0 0 NA NA NA NA NA NA 9083 XM_029340009.2 181 71 0 215 187 Q5ZLX5 6.76e-33 Zinc finger Ran-binding domain-containing protein 2 Gallus gallus (Chicken) RNA processing [GO:0006396] GO:0001530; GO:0003723; GO:0005634; GO:0006396; GO:0046872 9084 XM_044328265.1 131 134 83 107 97 P97739 3.32e-107 Endothelin-converting enzyme 1 (ECE-1) (EC 3.4.24.71) Cavia porcellus (Guinea pig) proteolysis [GO:0006508] GO:0004222; GO:0005886; GO:0006508; GO:0046872 9085 XM_044319696.1 57 42 62 0 0 Q3V050 1.31e-87 Multidrug and toxin extrusion protein 2 (MATE-2) (mMATE-2) (H(+)/organic cation antiporter kidney-specific) (Solute carrier family 47 member 2) Mus musculus (Mouse) organic cation transport [GO:0015695]; xenobiotic detoxification by transmembrane export across the plasma membrane [GO:1990961] GO:0005886; GO:0015101; GO:0015179; GO:0015297; GO:0015299; GO:0015695; GO:0016020; GO:0016323; GO:0016324; GO:0022857; GO:0042910; GO:0061459; GO:1990961 9086 XM_044315337.1 13 0 3 3 43 NA NA NA NA NA NA 9087 XM_044309339.1 0 0 0 0 7 NA NA NA NA NA NA 9088 XM_029336002.2 2763 2163 860 2224 2297 Q7XPW5 9.78e-108 Phosphomannomutase (OsPMM) (EC 5.4.2.8) Oryza sativa subsp. japonica (Rice) GDP-mannose biosynthetic process [GO:0009298]; mannose metabolic process [GO:0006013]; protein N-linked glycosylation [GO:0006487] GO:0004615; GO:0005829; GO:0006013; GO:0006487; GO:0009298; GO:0046872 9089 XM_029350476.2 18 8 6 3 4 Q04786 3.21e-176 Beta-hexosaminidase (EC 3.2.1.52) (Beta-N-acetylhexosaminidase) (Chitobiase) (N-acetyl-beta-glucosaminidase) Vibrio vulnificus chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272] GO:0000272; GO:0004563; GO:0006032; GO:0030247; GO:0102148 9090 XM_029342658.2 8 0 0 63 0 NA NA NA NA NA NA 9091 XM_029328673.2 765 1024 357 810 903 Q640I9 5.81e-171 Lysine-specific demethylase 2B (EC 1.14.11.27) (F-box and leucine-rich repeat protein 10) (F-box/LRR-repeat protein 10) (JmjC domain-containing histone demethylation protein 1B) ([Histone-H3]-lysine-36 demethylase 1B) Xenopus laevis (African clawed frog) chromatin organization [GO:0006325]; histone H3-K36 demethylation [GO:0070544] GO:0005634; GO:0005694; GO:0005730; GO:0006325; GO:0008270; GO:0019843; GO:0045322; GO:0051864; GO:0070544; GO:0140680 9092 XM_029328673.2 765 1024 357 810 903 Q640I9 2.69e-61 Lysine-specific demethylase 2B (EC 1.14.11.27) (F-box and leucine-rich repeat protein 10) (F-box/LRR-repeat protein 10) (JmjC domain-containing histone demethylation protein 1B) ([Histone-H3]-lysine-36 demethylase 1B) Xenopus laevis (African clawed frog) chromatin organization [GO:0006325]; histone H3-K36 demethylation [GO:0070544] GO:0005634; GO:0005694; GO:0005730; GO:0006325; GO:0008270; GO:0019843; GO:0045322; GO:0051864; GO:0070544; GO:0140680 9093 XM_044317512.1 20 6 35 3 50 NA NA NA NA NA NA 9094 XM_044318106.1 23 3 12 19 32 NA NA NA NA NA NA 9095 XR_006397689.1 11 13 187 0 1 NA NA NA NA NA NA 9096 XM_044322704.1 205 218 312 365 519 Q9NU22 0 Midasin (Dynein-related AAA-ATPase MDN1) (MIDAS-containing protein) Homo sapiens (Human) ribosomal large subunit assembly [GO:0000027]; ribosomal large subunit export from nucleus [GO:0000055] GO:0000027; GO:0000055; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005829; GO:0016020; GO:0016887; GO:0030687; GO:0045111 9097 XM_044322704.1 205 218 312 365 519 Q9NU22 3.53e-143 Midasin (Dynein-related AAA-ATPase MDN1) (MIDAS-containing protein) Homo sapiens (Human) ribosomal large subunit assembly [GO:0000027]; ribosomal large subunit export from nucleus [GO:0000055] GO:0000027; GO:0000055; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005829; GO:0016020; GO:0016887; GO:0030687; GO:0045111 9098 XM_044322704.1 205 218 312 365 519 Q9NU22 1e-121 Midasin (Dynein-related AAA-ATPase MDN1) (MIDAS-containing protein) Homo sapiens (Human) ribosomal large subunit assembly [GO:0000027]; ribosomal large subunit export from nucleus [GO:0000055] GO:0000027; GO:0000055; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005829; GO:0016020; GO:0016887; GO:0030687; GO:0045111 9099 XM_029355518.2 0 19 0 0 0 Q8NFF2 1.59e-116 Sodium/potassium/calcium exchanger 4 (Na(+)/K(+)/Ca(2+)-exchange protein 4) (Solute carrier family 24 member 4) Homo sapiens (Human) amelogenesis [GO:0097186]; calcium ion export across plasma membrane [GO:1990034]; calcium ion homeostasis [GO:0055074]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; cellular response to high light intensity [GO:0071486]; cone photoresponse recovery [GO:0036368]; detection of chemical stimulus involved in sensory perception of smell [GO:0050911]; drinking behavior [GO:0042756]; enamel mineralization [GO:0070166]; ion transport [GO:0006811]; membrane repolarization [GO:0086009]; negative regulation of calcium-mediated signaling [GO:0050849]; olfactory nerve maturation [GO:0021630]; phototransduction [GO:0007602]; positive regulation of gene expression [GO:0010628]; potassium ion transmembrane transport [GO:0071805]; regulation of eating behavior [GO:1903998]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; regulation of signaling receptor activity [GO:0010469]; response to high light intensity [GO:0009644]; response to melanocyte-stimulating hormone [GO:1990680]; response to odorant [GO:1990834]; sensory perception of smell [GO:0007608]; sodium ion transmembrane transport [GO:0035725] GO:0005262; GO:0005516; GO:0005737; GO:0005886; GO:0006811; GO:0006874; GO:0007602; GO:0007608; GO:0008273; GO:0008277; GO:0009644; GO:0010469; GO:0010628; GO:0015293; GO:0016020; GO:0016324; GO:0021630; GO:0031982; GO:0035725; GO:0036368; GO:0042756; GO:0048306; GO:0050849; GO:0050911; GO:0055074; GO:0070166; GO:0070588; GO:0071486; GO:0071805; GO:0086009; GO:0097186; GO:0098703; GO:0120199; GO:1903998; GO:1990034; GO:1990680; GO:1990834 9100 XM_029325626.2 74 51 23 57 129 NA NA NA NA NA NA 9101 XM_029331333.2 570 472 510 287 466 Q9YH18 5.99e-62 KH domain-containing RNA-binding protein QKI (Protein quaking) Gallus gallus (Chicken) long-chain fatty acid biosynthetic process [GO:0042759]; mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; myelination [GO:0042552]; positive regulation of gene expression [GO:0010628]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of translation [GO:0006417]; RNA splicing [GO:0008380]; spermatid development [GO:0007286]; vascular associated smooth muscle cell differentiation [GO:0035886]; vasculogenesis [GO:0001570] GO:0001570; GO:0003729; GO:0005634; GO:0005737; GO:0006397; GO:0006417; GO:0007286; GO:0008380; GO:0010628; GO:0017124; GO:0035886; GO:0042552; GO:0042759; GO:0045202; GO:0048024; GO:0051028 9102 XM_029341273.2 2115 1654 1091 1581 2469 Q58DA0 1.14e-118 26S proteasome non-ATPase regulatory subunit 4 (26S proteasome regulatory subunit RPN10) Bos taurus (Bovine) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] GO:0005634; GO:0005829; GO:0008540; GO:0022624; GO:0031593; GO:0043161 9103 XM_044320721.1 385 120 193 410 254 Q91Y77 4.27e-39 Monocarboxylate transporter 10 (MCT 10) (Aromatic amino acid transporter 1) (Solute carrier family 16 member 10) (T-type amino acid transporter 1) Rattus norvegicus (Rat) aromatic amino acid transport [GO:0015801]; thyroid hormone generation [GO:0006590]; thyroid hormone transport [GO:0070327]; thyroid-stimulating hormone secretion [GO:0070460] GO:0005302; GO:0005886; GO:0006590; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0070327; GO:0070460 9104 XM_044320721.1 385 120 193 410 254 Q91Y77 2.01e-26 Monocarboxylate transporter 10 (MCT 10) (Aromatic amino acid transporter 1) (Solute carrier family 16 member 10) (T-type amino acid transporter 1) Rattus norvegicus (Rat) aromatic amino acid transport [GO:0015801]; thyroid hormone generation [GO:0006590]; thyroid hormone transport [GO:0070327]; thyroid-stimulating hormone secretion [GO:0070460] GO:0005302; GO:0005886; GO:0006590; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0070327; GO:0070460 9105 XM_044314398.1 30 41 7 8 37 NA NA NA NA NA NA 9106 XM_029324625.2 0 0 0 0 74 NA NA NA NA NA NA 9107 XM_044328654.1 63 49 38 52 43 Q92820 5.23e-87 Gamma-glutamyl hydrolase (EC 3.4.19.9) (Conjugase) (GH) (Gamma-Glu-X carboxypeptidase) Homo sapiens (Human) tetrahydrofolylpolyglutamate metabolic process [GO:0046900] GO:0005576; GO:0005615; GO:0005634; GO:0005773; GO:0008238; GO:0008242; GO:0034722; GO:0035578; GO:0035580; GO:0042470; GO:0046900; GO:0070062; GO:1904724 9108 XM_044313366.1 4 0 15 0 6 Q09575 9.62e-33 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 9109 XM_044319530.1 11 28 0 6 0 NA NA NA NA NA NA 9110 XM_044307739.1 18 0 15 23 76 Q9U6Y6 1.44e-106 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 9111 XM_029348068.2 12 0 0 0 19 NA NA NA NA NA NA 9112 XM_029332309.2 1874 1539 1124 1601 1130 NA NA NA NA NA NA 9113 XM_044328548.1 204 80 35 113 40 Q6NVC5 0 Mitochondrial Rho GTPase 1-A (MIRO-1-A) (EC 3.6.5.-) (Ras homolog gene family member T1-A) Danio rerio (Zebrafish) (Brachydanio rerio) cellular homeostasis [GO:0019725]; mitochondrial outer membrane permeabilization [GO:0097345]; mitochondrion organization [GO:0007005]; mitochondrion transport along microtubule [GO:0047497]; regulation of mitochondrion organization [GO:0010821]; small GTPase mediated signal transduction [GO:0007264] GO:0003924; GO:0005509; GO:0005525; GO:0005739; GO:0005741; GO:0007005; GO:0007264; GO:0010821; GO:0019725; GO:0047497; GO:0097345 9114 XM_029337574.2 78 84 15 499 319 Q6GLK2 4.26e-31 Acyl-coenzyme A thioesterase THEM4 (Acyl-CoA thioesterase THEM4) (EC 3.1.2.2) (Thioesterase superfamily member 4) Xenopus laevis (African clawed frog) apoptotic process [GO:0006915]; fatty acid metabolic process [GO:0006631] GO:0005743; GO:0005758; GO:0006631; GO:0006915; GO:0016290; GO:0032587; GO:0102991 9115 XM_044319647.1 19 14 3 4 0 NA NA NA NA NA NA 9116 XM_029346743.2 59 20 15 27 55 NA NA NA NA NA NA 9117 XM_029354259.2 0 0 6 2 16 NA NA NA NA NA NA 9118 XR_006395781.1 829 625 287 535 576 Q96MG7 2.26e-36 Non-structural maintenance of chromosomes element 3 homolog (Non-SMC element 3 homolog) (Hepatocellular carcinoma-associated protein 4) (MAGE-G1 antigen) (Melanoma-associated antigen G1) (Necdin-like protein 2) Homo sapiens (Human) cellular response to hydroxyurea [GO:0072711]; cellular response to radiation [GO:0071478]; cellular response to UV [GO:0034644]; DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of protein ubiquitination [GO:0031398]; protein sumoylation [GO:0016925]; regulation of telomere maintenance [GO:0032204] GO:0000122; GO:0000724; GO:0000781; GO:0005634; GO:0005654; GO:0005737; GO:0006281; GO:0016925; GO:0030915; GO:0031398; GO:0032204; GO:0034644; GO:0046983; GO:0071478; GO:0072711 9119 XM_029358160.2 1293 916 710 855 899 Q8NBP5 3.54e-65 Major facilitator superfamily domain-containing protein 9 Homo sapiens (Human) NA GO:0016020; GO:0022857 9120 XM_044322633.1 18 0 15 14 12 NA NA NA NA NA NA 9121 XR_006394141.1 15 0 29 0 93 NA NA NA NA NA NA 9122 XM_044327557.1 1794 623 225 645 1738 NA NA NA NA NA NA 9123 XM_029334714.2 240 72 203 328 149 Q66JY2 5.92e-39 INO80 complex subunit D Mus musculus (Mouse) chromatin remodeling [GO:0006338]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of telomere maintenance in response to DNA damage [GO:1904507]; regulation of cell cycle [GO:0051726]; regulation of chromosome organization [GO:0033044]; regulation of DNA repair [GO:0006282]; regulation of DNA replication [GO:0006275]; regulation of DNA strand elongation [GO:0060382]; regulation of embryonic development [GO:0045995]; telomere maintenance [GO:0000723] GO:0000723; GO:0005634; GO:0006275; GO:0006281; GO:0006282; GO:0006310; GO:0006338; GO:0031011; GO:0033044; GO:0045739; GO:0045893; GO:0045995; GO:0051726; GO:0060382; GO:1904507 9124 XM_029332206.2 4 0 38 5 3 NA NA NA NA NA NA 9125 XM_044310848.1 0 89 0 0 0 Q99570 2.72e-36 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 9126 XM_044306849.1 0 19 0 3 44 A7SIM4 0 Hapless 2 (Generative cell specific 1) Nematostella vectensis (Starlet sea anemone) single fertilization [GO:0007338] GO:0005886; GO:0007338; GO:0008289 9127 XR_006392702.1 18 0 5 0 0 NA NA NA NA NA NA 9128 XM_029337919.2 15 1 0 0 0 NA NA NA NA NA NA 9129 XR_003828577.2 20 4 28 4 34 NA NA NA NA NA NA 9130 XM_029349872.2 222 116 116 242 163 Q6IRI9 2.5e-39 Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.-) (Dimethylaniline oxidase 2) (Pulmonary flavin-containing monooxygenase 2) (FMO 2) Rattus norvegicus (Rat) energy homeostasis [GO:0097009]; NADP metabolic process [GO:0006739]; NADPH oxidation [GO:0070995]; negative regulation of fatty acid oxidation [GO:0046322]; organic acid metabolic process [GO:0006082]; oxygen metabolic process [GO:0072592]; toxin metabolic process [GO:0009404]; xenobiotic metabolic process [GO:0006805] GO:0004497; GO:0004499; GO:0005789; GO:0006082; GO:0006739; GO:0006805; GO:0009404; GO:0016020; GO:0046322; GO:0047822; GO:0050660; GO:0050661; GO:0070995; GO:0072592; GO:0097009 9131 XM_029345450.2 12 0 15 0 0 P55112 1.4e-40 Zinc metalloproteinase nas-4 (EC 3.4.24.-) (Nematode astacin 4) Caenorhabditis elegans proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0006508; GO:0008270 9132 XM_029352029.2 230 135 53 134 126 Q08CH6 3.54e-72 Ciliogenesis-associated TTC17-interacting protein Danio rerio (Zebrafish) (Brachydanio rerio) actin filament polymerization [GO:0030041]; cilium assembly [GO:0060271]; cilium organization [GO:0044782]; determination of heart left/right asymmetry [GO:0061371] GO:0005634; GO:0005737; GO:0005886; GO:0015629; GO:0030041; GO:0044782; GO:0060271; GO:0061371 9133 XM_029339103.2 1 17 0 1 22 NA NA NA NA NA NA 9134 XM_044314256.1 8 5 0 7 0 P81274 5.19e-42 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 9135 XM_044314256.1 8 5 0 7 0 P81274 1.39e-34 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 9136 XM_044314256.1 8 5 0 7 0 P81274 4.34e-27 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 9137 XM_029335411.2 3400 3976 1280 3150 1364 NA NA NA NA NA NA 9138 XM_029337526.2 63 89 14 40 12 P9WM79 7.13e-79 Probable polyglutamine synthesis accessory protein Rv0574c Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) NA NA 9139 XM_029330670.2 1446 888 839 583 1093 Q9NXC2 2.43e-102 Glucose-fructose oxidoreductase domain-containing protein 1 (EC 1.-.-.-) Homo sapiens (Human) NA GO:0000166; GO:0005576; GO:0016491 9140 XM_029324443.2 171 81 0 293 214 Q96I24 2.63e-72 Far upstream element-binding protein 3 (FUSE-binding protein 3) Homo sapiens (Human) DNA-templated transcription [GO:0006351]; intracellular mRNA localization [GO:0008298]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression [GO:0010468] GO:0003697; GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0005737; GO:0005840; GO:0005844; GO:0006351; GO:0008298; GO:0010468; GO:0010628; GO:0016020; GO:0043025; GO:0043198; GO:0045893; GO:0045944 9141 XM_044326179.1 36 33 49 40 2 NA NA NA NA NA NA 9142 XR_006396436.1 4 36 1 5 18 NA NA NA NA NA NA 9143 XM_044307469.1 3 14 8 14 30 Q09575 4.09e-21 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 9144 XM_029353882.2 265 343 50 149 107 P82649 2.25e-85 28S ribosomal protein S22, mitochondrial (MRP-S22) (S22mt) Bos taurus (Bovine) mitochondrial translation [GO:0032543] GO:0003735; GO:0005743; GO:0005763; GO:0032543 9145 XM_044324447.1 29 405 879 823 2921 NA NA NA NA NA NA 9146 XM_029356342.2 13 370 2 8 8 Q8CIQ7 0 Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP) Mus musculus (Mouse) small GTPase mediated signal transduction [GO:0007264] GO:0005085; GO:0005096; GO:0005737; GO:0005829; GO:0005886; GO:0007264; GO:0017124; GO:0031267 9147 XM_029335490.2 820 975 663 1141 901 Q9H3E2 0 Sorting nexin-25 Homo sapiens (Human) negative regulation of pathway-restricted SMAD protein phosphorylation [GO:0060394]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; protein transport [GO:0015031]; receptor catabolic process [GO:0032801] GO:0005768; GO:0010008; GO:0015031; GO:0030512; GO:0032801; GO:0035091; GO:0043231; GO:0060394 9148 XM_029358181.2 0 0 0 31 17 E9PZZ1 4.26e-26 PR domain zinc finger protein 13 (EC 2.1.1.-) (PR domain-containing protein 13) Mus musculus (Mouse) GABAergic neuron differentiation [GO:0097154]; hypothalamus cell differentiation [GO:0021979]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of gene expression [GO:0010468] GO:0000122; GO:0003677; GO:0003682; GO:0005634; GO:0010468; GO:0021979; GO:0022008; GO:0042054; GO:0046872; GO:0061629; GO:0097154 9149 XM_029333899.2 649 357 387 751 275 Q9UHJ3 7.22e-58 Scm-like with four MBT domains protein 1 (hSFMBT) (Renal ubiquitous protein 1) Homo sapiens (Human) cell differentiation [GO:0030154]; chromatin organization [GO:0006325]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of muscle organ development [GO:0048635]; spermatogenesis [GO:0007283] GO:0003682; GO:0003714; GO:0005634; GO:0005654; GO:0006325; GO:0007283; GO:0030154; GO:0042393; GO:0045892; GO:0048635 9150 XM_029333899.2 649 357 387 751 275 Q9UHJ3 4.87e-32 Scm-like with four MBT domains protein 1 (hSFMBT) (Renal ubiquitous protein 1) Homo sapiens (Human) cell differentiation [GO:0030154]; chromatin organization [GO:0006325]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of muscle organ development [GO:0048635]; spermatogenesis [GO:0007283] GO:0003682; GO:0003714; GO:0005634; GO:0005654; GO:0006325; GO:0007283; GO:0030154; GO:0042393; GO:0045892; GO:0048635 9151 XM_044325719.1 6 7 0 5 14 NA NA NA NA NA NA 9152 XM_044322462.1 519 278 80 200 389 Q96AY4 5.22e-82 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9153 XM_044322462.1 519 278 80 200 389 Q96AY4 1.21e-80 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9154 XM_044322462.1 519 278 80 200 389 Q96AY4 5.44e-77 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9155 XM_044322462.1 519 278 80 200 389 Q96AY4 8.76e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9156 XM_044322462.1 519 278 80 200 389 Q96AY4 1.82e-62 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9157 XM_044322462.1 519 278 80 200 389 Q96AY4 1.13e-49 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9158 XM_044313221.1 9 13 5 3 15 Q3SZD5 6.49e-26 DDB1- and CUL4-associated factor 15 Bos taurus (Bovine) immune system process [GO:0002376]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of natural killer cell activation [GO:0032814] GO:0000209; GO:0002376; GO:0016567; GO:0032814; GO:0036094; GO:0046872; GO:0080008 9159 XM_044322783.1 25 23 7 0 5 Q94887 9.8e-30 Neurexin-4 (Neurexin IV) Drosophila melanogaster (Fruit fly) axon ensheathment [GO:0008366]; cell adhesion involved in heart morphogenesis [GO:0061343]; cell-cell junction organization [GO:0045216]; dorsal closure [GO:0007391]; establishment of glial blood-brain barrier [GO:0060857]; heart process [GO:0003015]; nerve maturation [GO:0021682]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]; synaptic target recognition [GO:0008039]; terminal button organization [GO:0072553] GO:0003015; GO:0005886; GO:0005919; GO:0007391; GO:0008039; GO:0008104; GO:0008366; GO:0019991; GO:0021682; GO:0035151; GO:0045202; GO:0045216; GO:0048786; GO:0060857; GO:0061343; GO:0072553; GO:0097105 9160 XM_029343495.2 652 214 108 177 113 NA NA NA NA NA NA 9161 XM_029337166.2 23 15 25 8 30 NA NA NA NA NA NA 9162 XM_029352448.2 53 3 12 57 53 Q9UGM3 1.39e-53 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 9163 XM_029352448.2 53 3 12 57 53 Q9UGM3 4.65e-51 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 9164 XM_029352448.2 53 3 12 57 53 Q9UGM3 6.17e-51 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 9165 XM_029352448.2 53 3 12 57 53 Q9UGM3 1.15e-50 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 9166 XM_029352448.2 53 3 12 57 53 Q9UGM3 1.41e-50 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 9167 XM_029352448.2 53 3 12 57 53 Q9UGM3 3.32e-50 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 9168 XM_029352448.2 53 3 12 57 53 Q9UGM3 4.06e-50 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 9169 XM_029352448.2 53 3 12 57 53 Q9UGM3 5.18e-50 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 9170 XM_029352448.2 53 3 12 57 53 Q9UGM3 6.85e-50 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 9171 XM_029352448.2 53 3 12 57 53 Q9UGM3 1.01e-49 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 9172 XM_029352448.2 53 3 12 57 53 Q9UGM3 4.34e-33 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 9173 XR_006393089.1 41 2 25 5 151 NA NA NA NA NA NA 9174 XM_044313766.1 1259 1000 1147 1099 1674 Q6UPE0 0 Choline dehydrogenase, mitochondrial (CDH) (CHD) (EC 1.1.99.1) Rattus norvegicus (Rat) glycine betaine biosynthetic process from choline [GO:0019285] GO:0005743; GO:0008812; GO:0016491; GO:0019285; GO:0050660 9175 XM_044325705.1 0 0 2 192 0 Q12789 7.4e-72 General transcription factor 3C polypeptide 1 (TF3C-alpha) (TFIIIC box B-binding subunit) (Transcription factor IIIC 220 kDa subunit) (TFIIIC 220 kDa subunit) (TFIIIC220) (Transcription factor IIIC subunit alpha) Homo sapiens (Human) 5S class rRNA transcription by RNA polymerase III [GO:0042791]; rRNA transcription [GO:0009303]; transcription by RNA polymerase III [GO:0006383]; transcription initiation at RNA polymerase III promoter [GO:0006384]; tRNA transcription [GO:0009304]; tRNA transcription by RNA polymerase III [GO:0042797] GO:0000127; GO:0000995; GO:0003677; GO:0005654; GO:0005730; GO:0006383; GO:0006384; GO:0009303; GO:0009304; GO:0016020; GO:0042791; GO:0042797; GO:1990904 9176 XM_044325705.1 0 0 2 192 0 Q12789 5.47e-45 General transcription factor 3C polypeptide 1 (TF3C-alpha) (TFIIIC box B-binding subunit) (Transcription factor IIIC 220 kDa subunit) (TFIIIC 220 kDa subunit) (TFIIIC220) (Transcription factor IIIC subunit alpha) Homo sapiens (Human) 5S class rRNA transcription by RNA polymerase III [GO:0042791]; rRNA transcription [GO:0009303]; transcription by RNA polymerase III [GO:0006383]; transcription initiation at RNA polymerase III promoter [GO:0006384]; tRNA transcription [GO:0009304]; tRNA transcription by RNA polymerase III [GO:0042797] GO:0000127; GO:0000995; GO:0003677; GO:0005654; GO:0005730; GO:0006383; GO:0006384; GO:0009303; GO:0009304; GO:0016020; GO:0042791; GO:0042797; GO:1990904 9177 XM_029327428.2 57 34 0 36 149 P63138 3.46e-69 Gamma-aminobutyric acid receptor subunit beta-2 (GABA(A) receptor subunit beta-2) Rattus norvegicus (Rat) cellular response to histamine [GO:0071420]; chemical synaptic transmission [GO:0007268]; chemical synaptic transmission, postsynaptic [GO:0099565]; chloride transmembrane transport [GO:1902476]; cochlea development [GO:0090102]; gamma-aminobutyric acid signaling pathway [GO:0007214]; inhibitory synapse assembly [GO:1904862]; inner ear receptor cell development [GO:0060119]; innervation [GO:0060384]; ion transmembrane transport [GO:0034220]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; nervous system process [GO:0050877]; neuron development [GO:0048666]; regulation of membrane potential [GO:0042391]; regulation of neuron apoptotic process [GO:0043523]; regulation of postsynaptic membrane potential [GO:0060078]; sensory perception of sound [GO:0007605]; signal transduction [GO:0007165]; synaptic transmission, GABAergic [GO:0051932] GO:0004890; GO:0005231; GO:0005237; GO:0005254; GO:0005829; GO:0005886; GO:0007165; GO:0007214; GO:0007268; GO:0007605; GO:0016020; GO:0022851; GO:0030594; GO:0030659; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0043523; GO:0043524; GO:0045202; GO:0048666; GO:0048787; GO:0050877; GO:0051932; GO:0060078; GO:0060119; GO:0060384; GO:0071420; GO:0090102; GO:0098978; GO:0098982; GO:0099507; GO:0099565; GO:0099634; GO:1901215; GO:1902476; GO:1902710; GO:1902711; GO:1904315; GO:1904862 9178 XM_044322066.1 81 64 0 63 0 Q7RTR2 3.2e-25 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 9179 XM_044322066.1 81 64 0 63 0 Q7RTR2 7.38e-23 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 9180 XR_006395757.1 1222 1009 731 1137 1069 NA NA NA NA NA NA 9181 XR_006393399.1 0 0 12 27 57 NA NA NA NA NA NA 9182 XM_044308743.1 25 1 1 23 0 NA NA NA NA NA NA 9183 XM_029324190.2 12 0 2 0 8 NA NA NA NA NA NA 9184 XM_029353835.2 101 1 43 0 129 NA NA NA NA NA NA 9185 XM_029330441.2 5588 2515 1733 2665 4198 NA NA NA NA NA NA 9186 XM_044314887.1 78 4 0 6 3 NA NA NA NA NA NA 9187 XM_029328796.2 184 66 72 168 406 Q14184 6.46e-95 Double C2-like domain-containing protein beta (Doc2-beta) Homo sapiens (Human) calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-dependent activation of synaptic vesicle fusion [GO:0099502]; exocytosis [GO:0006887]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of insulin secretion [GO:0032024]; positive regulation of vesicle fusion [GO:0031340]; protein localization [GO:0008104]; regulation of calcium ion-dependent exocytosis [GO:0017158]; spontaneous neurotransmitter secretion [GO:0061669] GO:0005509; GO:0005544; GO:0005737; GO:0005886; GO:0006887; GO:0008104; GO:0017158; GO:0019905; GO:0031340; GO:0032024; GO:0045202; GO:0045956; GO:0048791; GO:0061669; GO:0098793; GO:0099502 9188 XM_044322631.1 0 0 6 9 9 NA NA NA NA NA NA 9189 XM_029336418.2 466 386 382 664 912 Q149F3 0 Eukaryotic peptide chain release factor GTP-binding subunit ERF3B (Eukaryotic peptide chain release factor subunit 3b) (eRF3b) (G1 to S phase transition protein 2 homolog) Mus musculus (Mouse) cell cycle [GO:0007049]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; translation [GO:0006412] GO:0000184; GO:0003747; GO:0003924; GO:0005525; GO:0006412; GO:0007049; GO:0018444 9190 XM_044319393.1 34 30 14 6 16 NA NA NA NA NA NA 9191 XM_044314612.1 3320 1031 2683 1824 1117 NA NA NA NA NA NA 9192 XM_044312425.1 0 79 0 48 0 NA NA NA NA NA NA 9193 XM_044318022.1 60 7 2 37 77 NA NA NA NA NA NA 9194 XR_006396697.1 5 0 0 0 12 NA NA NA NA NA NA 9195 XM_029339477.2 20205 24068 15548 27095 22883 O00560 1.03e-106 Syntenin-1 (Melanoma differentiation-associated protein 9) (MDA-9) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18) (Scaffold protein Pbp1) (Syndecan-binding protein 1) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; chemical synaptic transmission [GO:0007268]; intracellular signal transduction [GO:0035556]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of receptor internalization [GO:0002091]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of extracellular exosome assembly [GO:1903553]; positive regulation of JNK cascade [GO:0046330]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; presynapse assembly [GO:0099054]; protein targeting to membrane [GO:0006612]; proteolysis [GO:0006508]; Ras protein signal transduction [GO:0007265]; regulation of mitotic cell cycle [GO:0007346]; substrate-dependent cell migration, cell extension [GO:0006930] GO:0000122; GO:0002091; GO:0004222; GO:0005109; GO:0005137; GO:0005546; GO:0005576; GO:0005615; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005789; GO:0005829; GO:0005856; GO:0005886; GO:0005895; GO:0005912; GO:0005925; GO:0006508; GO:0006612; GO:0006930; GO:0007265; GO:0007268; GO:0007346; GO:0008022; GO:0008093; GO:0008284; GO:0010718; GO:0010862; GO:0014069; GO:0016020; GO:0019838; GO:0030036; GO:0030307; GO:0030335; GO:0030511; GO:0031965; GO:0032435; GO:0035255; GO:0035556; GO:0035578; GO:0042043; GO:0042327; GO:0042470; GO:0042802; GO:0044877; GO:0045121; GO:0045545; GO:0046330; GO:0046875; GO:0046982; GO:0047485; GO:0050839; GO:0070062; GO:0072562; GO:0098793; GO:0099054; GO:1903543; GO:1903553; GO:1903561 9196 XM_044322796.1 0 0 0 0 41 NA NA NA NA NA NA 9197 XM_029344044.2 24 43 41 31 20 NA NA NA NA NA NA 9198 XR_006396614.1 124 316 194 136 149 NA NA NA NA NA NA 9199 XR_006393604.1 7 5 2 38 40 NA NA NA NA NA NA 9200 XM_029341845.2 467 337 339 416 568 Q6UXM1 3.67e-59 Leucine-rich repeats and immunoglobulin-like domains protein 3 (LIG-3) Homo sapiens (Human) otolith morphogenesis [GO:0032474] GO:0005615; GO:0005886; GO:0030659; GO:0031012; GO:0032474 9201 XR_006395885.1 11 0 10 0 0 NA NA NA NA NA NA 9202 XM_029333371.2 3550 4732 1343 3585 1776 NA NA NA NA NA NA 9203 XR_006393819.1 56 25 15 20 84 NA NA NA NA NA NA 9204 XM_029347391.2 38 17 10 18 21 Q58DT4 7.92e-69 Pyrroline-5-carboxylate reductase 1, mitochondrial (P5C reductase 1) (P5CR 1) (EC 1.5.1.2) Bos taurus (Bovine) cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; proline biosynthetic process [GO:0006561] GO:0004735; GO:0005739; GO:0006561; GO:0034599; GO:0055129 9205 XM_029334148.2 46 42 7 33 45 Q0VAW7 4.55e-72 Zinc finger protein 112 (Zfp-112) Mus musculus (Mouse) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 9206 XM_029334148.2 46 42 7 33 45 Q0VAW7 1.48e-60 Zinc finger protein 112 (Zfp-112) Mus musculus (Mouse) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 9207 XM_029334148.2 46 42 7 33 45 Q0VAW7 2.16e-49 Zinc finger protein 112 (Zfp-112) Mus musculus (Mouse) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 9208 XM_029334148.2 46 42 7 33 45 Q0VAW7 1.26e-46 Zinc finger protein 112 (Zfp-112) Mus musculus (Mouse) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 9209 XM_029334148.2 46 42 7 33 45 Q0VAW7 4.21e-30 Zinc finger protein 112 (Zfp-112) Mus musculus (Mouse) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 9210 XM_029330686.2 0 0 0 109 144 Q9Y6F7 8.13e-38 Testis-specific chromodomain protein Y 2 (EC 2.3.1.48) Homo sapiens (Human) spermatogenesis [GO:0007283] GO:0003714; GO:0004402; GO:0005634; GO:0007283 9211 XM_044327218.1 728 660 459 775 498 Q96AJ1 9.66e-122 Clusterin-associated protein 1 (Qilin) Homo sapiens (Human) axoneme assembly [GO:0035082]; cilium assembly [GO:0060271]; floor plate formation [GO:0021508]; heart looping [GO:0001947]; intraciliary anterograde transport [GO:0035720]; neural tube closure [GO:0001843]; smoothened signaling pathway [GO:0007224] GO:0001843; GO:0001947; GO:0005654; GO:0005813; GO:0005929; GO:0007224; GO:0021508; GO:0030991; GO:0030992; GO:0035082; GO:0035720; GO:0043231; GO:0060271; GO:0097542; GO:0097546 9212 XM_029350817.2 1638 1178 1088 2306 2089 A0A1U8QWA2 0 Glycine betaine reductase ATRR (Nonribosomal peptide synthetase-like protein ATRR) [Includes: Carboxylic acid reductase (EC 1.2.1.-); Aldehyde reductase (EC 1.1.1.-)] Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) metabolic process [GO:0008152] GO:0008152; GO:0016491; GO:0031177 9213 XM_029351884.2 250 207 165 241 336 NA NA NA NA NA NA 9214 XR_006397867.1 0 0 0 27 13 Q86U44 1.72e-145 N6-adenosine-methyltransferase catalytic subunit (EC 2.1.1.348) (Methyltransferase-like protein 3) (hMETTL3) (N6-adenosine-methyltransferase 70 kDa subunit) (MT-A70) Homo sapiens (Human) adenosine to inosine editing [GO:0006382]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; circadian rhythm [GO:0007623]; dosage compensation by inactivation of X chromosome [GO:0009048]; endothelial to hematopoietic transition [GO:0098508]; forebrain radial glial cell differentiation [GO:0021861]; gliogenesis [GO:0042063]; innate immune response [GO:0045087]; mRNA catabolic process [GO:0006402]; mRNA destabilization [GO:0061157]; mRNA methylation [GO:0080009]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; oogenesis [GO:0048477]; positive regulation of cap-independent translational initiation [GO:1903679]; positive regulation of translation [GO:0045727]; primary miRNA processing [GO:0031053]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of meiotic cell cycle [GO:0051445]; regulation of T cell differentiation [GO:0045580]; RNA methylation [GO:0001510]; spermatogenesis [GO:0007283]; stem cell population maintenance [GO:0019827] GO:0000398; GO:0001510; GO:0001734; GO:0003729; GO:0005634; GO:0005654; GO:0005737; GO:0006382; GO:0006397; GO:0006402; GO:0006974; GO:0007283; GO:0007623; GO:0008168; GO:0008173; GO:0009048; GO:0016422; GO:0016607; GO:0019827; GO:0021861; GO:0031053; GO:0034644; GO:0036396; GO:0042063; GO:0045087; GO:0045580; GO:0045727; GO:0045746; GO:0046982; GO:0048477; GO:0051445; GO:0060339; GO:0061157; GO:0080009; GO:0098508; GO:1902036; GO:1903679; GO:1904047 9215 XM_044308378.1 5024 1328 918 3726 3883 Q61838 2.19e-173 Pregnancy zone protein (Alpha-2-macroglobulin) (Alpha-2-M) [Cleaved into: Alpha-2-macroglobulin 165 kDa subunit; Alpha-2-macroglobulin 35 kDa subunit] Mus musculus (Mouse) embryo implantation [GO:0007566]; negative regulation of peptidase activity [GO:0010466] GO:0002020; GO:0004866; GO:0004867; GO:0005576; GO:0005615; GO:0007566; GO:0010466; GO:0044877; GO:0048403; GO:0048406; GO:0062023 9216 XM_044308378.1 5024 1328 918 3726 3883 Q61838 2.19e-173 Pregnancy zone protein (Alpha-2-macroglobulin) (Alpha-2-M) [Cleaved into: Alpha-2-macroglobulin 165 kDa subunit; Alpha-2-macroglobulin 35 kDa subunit] Mus musculus (Mouse) embryo implantation [GO:0007566]; negative regulation of peptidase activity [GO:0010466] GO:0002020; GO:0004866; GO:0004867; GO:0005576; GO:0005615; GO:0007566; GO:0010466; GO:0044877; GO:0048403; GO:0048406; GO:0062023 9217 XM_044318929.1 183 129 113 368 255 Q99961 1.62e-82 Endophilin-A2 (EEN fusion partner of MLL) (Endophilin-2) (Extra eleven-nineteen leukemia fusion gene protein) (EEN) (SH3 domain protein 2B) (SH3 domain-containing GRB2-like protein 1) Homo sapiens (Human) central nervous system development [GO:0007417]; signal transduction [GO:0007165]; synaptic vesicle uncoating [GO:0016191] GO:0002102; GO:0005737; GO:0005829; GO:0007165; GO:0007417; GO:0008289; GO:0016191; GO:0031901; GO:0042802; GO:0042995; GO:0045296; GO:0070161; GO:0098793; GO:0098978 9218 XM_044324287.1 0 27 0 0 0 Q76IC6 2.06e-53 Palmitoyltransferase ZDHHC23 (EC 2.3.1.225) (NNOS-interacting DHHC domain-containing protein with dendritic mRNA) (Zinc finger DHHC domain-containing protein 23) (DHHC-23) (zDHHC23) Rattus norvegicus (Rat) peptidyl-L-cysteine S-palmitoylation [GO:0018230]; protein localization to plasma membrane [GO:0072659]; protein palmitoylation [GO:0018345]; protein targeting to membrane [GO:0006612] GO:0000139; GO:0005783; GO:0005794; GO:0006612; GO:0018230; GO:0018345; GO:0019706; GO:0072659 9219 XM_044318121.1 299 76 217 250 269 E9Q236 0 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 9220 XM_044312996.1 20 34 2 34 34 NA NA NA NA NA NA 9221 XR_006391876.1 0 1 1 8 10 Q91XJ1 6.92e-21 Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197) [Cleaved into: Beclin-1-C 35 kDa; Beclin-1-C 37 kDa] Rattus norvegicus (Rat) aging [GO:0007568]; amyloid-beta metabolic process [GO:0050435]; apoptotic process [GO:0006915]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cell division [GO:0051301]; cellular response to aluminum ion [GO:0071275]; cellular response to amino acid starvation [GO:0034198]; cellular response to copper ion [GO:0071280]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucose starvation [GO:0042149]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to nitrogen starvation [GO:0006995]; defense response to virus [GO:0051607]; early endosome to late endosome transport [GO:0045022]; engulfment of apoptotic cell [GO:0043652]; late endosome to vacuole transport [GO:0045324]; lysosome organization [GO:0007040]; macroautophagy [GO:0016236]; mitophagy [GO:0000423]; mitotic metaphase plate congression [GO:0007080]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagosome assembly [GO:1902902]; negative regulation of autophagy [GO:0010507]; negative regulation of cell death [GO:0060548]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of lysosome organization [GO:1905672]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; neuron development [GO:0048666]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of attachment of mitotic spindle microtubules to kinetochore [GO:1902425]; positive regulation of autophagosome assembly [GO:2000786]; positive regulation of autophagy [GO:0010508]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; protein phosphorylation [GO:0006468]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of catalytic activity [GO:0050790]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241]; response to hypoxia [GO:0001666]; response to iron(II) ion [GO:0010040]; response to lead ion [GO:0010288]; response to mitochondrial depolarisation [GO:0098780]; response to nutrient levels [GO:0031667]; response to other organism [GO:0051707]; response to vitamin E [GO:0033197]; response to xenobiotic stimulus [GO:0009410]; selective autophagy [GO:0061912] GO:0000045; GO:0000407; GO:0000422; GO:0000423; GO:0001666; GO:0005634; GO:0005737; GO:0005768; GO:0005776; GO:0005783; GO:0005789; GO:0005802; GO:0005829; GO:0006468; GO:0006914; GO:0006915; GO:0006995; GO:0007040; GO:0007080; GO:0007568; GO:0008285; GO:0009410; GO:0010008; GO:0010040; GO:0010288; GO:0010506; GO:0010507; GO:0010508; GO:0010613; GO:0016236; GO:0016241; GO:0016604; GO:0019898; GO:0019901; GO:0030425; GO:0031410; GO:0031625; GO:0031667; GO:0031966; GO:0032465; GO:0032801; GO:0032991; GO:0033197; GO:0034198; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0042802; GO:0043066; GO:0043548; GO:0043652; GO:0045022; GO:0045324; GO:0045335; GO:0048666; GO:0050435; GO:0050790; GO:0051020; GO:0051301; GO:0051607; GO:0051707; GO:0060548; GO:0061912; GO:0070301; GO:0071275; GO:0071280; GO:0071364; GO:0097352; GO:0098780; GO:1902425; GO:1902902; GO:1905672; GO:2000378; GO:2000786; GO:2001244 9222 XM_029343193.2 414 135 38 271 153 Q9QYB2 3.04e-29 Dachshund homolog 1 (Dach1) Mus musculus (Mouse) development of primary female sexual characteristics [GO:0046545]; epithelial cell proliferation [GO:0050673]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation involved in contact inhibition [GO:0060244]; negative regulation of DNA biosynthetic process [GO:2000279]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of transcription by competitive promoter binding [GO:0010944]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355]; regulation of nuclear cell cycle DNA replication [GO:0033262]; regulation of transcription by RNA polymerase II [GO:0006357]; respiratory gaseous exchange by respiratory system [GO:0007585]; suckling behavior [GO:0001967]; type B pancreatic cell proliferation [GO:0044342] GO:0000122; GO:0000977; GO:0000978; GO:0000981; GO:0001227; GO:0001967; GO:0003700; GO:0005634; GO:0005654; GO:0005667; GO:0005737; GO:0005794; GO:0005829; GO:0006355; GO:0006357; GO:0007585; GO:0010944; GO:0016607; GO:0030336; GO:0033262; GO:0044342; GO:0045892; GO:0046545; GO:0048147; GO:0050673; GO:0060244; GO:2000279 9223 XM_029330707.2 106 73 60 109 68 P56377 6.05e-90 AP-1 complex subunit sigma-2 (Adaptor protein complex AP-1 subunit sigma-1B) (Adaptor-related protein complex 1 subunit sigma-1B) (Clathrin assembly protein complex 1 sigma-1B small chain) (Golgi adaptor HA1/AP1 adaptin sigma-1B subunit) (Sigma 1B subunit of AP-1 clathrin) (Sigma-adaptin 1B) (Sigma1B-adaptin) Homo sapiens (Human) intracellular protein transport [GO:0006886]; melanosome assembly [GO:1903232]; platelet dense granule organization [GO:0060155]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0005765; GO:0005769; GO:0005794; GO:0005829; GO:0005905; GO:0006886; GO:0016192; GO:0030119; GO:0030121; GO:0030659; GO:0032588; GO:0035615; GO:0043231; GO:0060155; GO:1903232 9224 XR_006394266.1 11 4 43 9 189 NA NA NA NA NA NA 9225 XM_029357095.2 0 0 61 129 115 NA NA NA NA NA NA 9226 XM_044316645.1 185 285 262 486 457 NA NA NA NA NA NA 9227 XM_044321472.1 88 152 125 129 92 Q6P1S4 0 Arginine--tRNA ligase, cytoplasmic (EC 6.1.1.19) (Arginyl-tRNA synthetase) (ArgRS) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) arginyl-tRNA aminoacylation [GO:0006420] GO:0004814; GO:0005524; GO:0005829; GO:0006420; GO:0017101 9228 XM_044308347.1 108 151 61 91 193 NA NA NA NA NA NA 9229 XM_044316088.1 4 4 0 0 24 A8MZ26 1.42e-51 EF-hand calcium-binding domain-containing protein 9 Homo sapiens (Human) flagellated sperm motility [GO:0030317]; sperm capacitation [GO:0048240]; spermatogenesis [GO:0007283] GO:0005509; GO:0005737; GO:0007283; GO:0030317; GO:0036128; GO:0048240; GO:0061891; GO:0097228 9230 XR_006397982.1 626 1077 600 848 1380 NA NA NA NA NA NA 9231 XM_029342331.2 575 179 113 943 1316 NA NA NA NA NA NA 9232 XM_044309330.1 0 0 0 6 0 NA NA NA NA NA NA 9233 XM_029331670.2 23 91 17 45 22 Q76L87 9.96e-33 Doublesex- and mab-3-related transcription factor A2 (Doublesex- and mab-3-related transcription factor 5) (Ola-DMRT5) Oryzias latipes (Japanese rice fish) (Japanese killifish) regulation of transcription by RNA polymerase II [GO:0006357]; sex differentiation [GO:0007548] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0007548; GO:0046872 9234 XR_006392432.1 48 34 23 64 56 NA NA NA NA NA NA 9235 XR_006394967.1 2 2 34 47 38 Q75N90 4.66e-44 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 9236 XR_006394967.1 2 2 34 47 38 Q75N90 1.05e-36 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 9237 XR_006394967.1 2 2 34 47 38 Q75N90 4.29e-28 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 9238 XR_006394967.1 2 2 34 47 38 Q75N90 9.73e-26 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 9239 XR_006394967.1 2 2 34 47 38 Q75N90 2.08e-24 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 9240 XR_006394967.1 2 2 34 47 38 Q75N90 4.1e-24 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 9241 XR_006394967.1 2 2 34 47 38 Q75N90 6.83e-23 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 9242 XR_006394967.1 2 2 34 47 38 Q75N90 2.42e-22 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 9243 XR_006394967.1 2 2 34 47 38 Q75N90 1.12e-21 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 9244 XR_006394967.1 2 2 34 47 38 Q75N90 1.55e-21 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 9245 XM_029345009.2 34 0 7 23 0 NA NA NA NA NA NA 9246 XM_044318662.1 183 128 99 180 0 O75899 9.76e-72 Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51) (HG20) Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway [GO:0007186]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; neuron-glial cell signaling [GO:0150099]; synaptic transmission, GABAergic [GO:0051932] GO:0004888; GO:0004965; GO:0005737; GO:0005886; GO:0007186; GO:0007193; GO:0007194; GO:0007214; GO:0007268; GO:0038039; GO:0043005; GO:0045211; GO:0046982; GO:0051932; GO:0150099; GO:1902710; GO:1902712 9247 XR_003825088.2 6 0 0 13 0 NA NA NA NA NA NA 9248 XM_029342107.2 0 20 0 0 19 NA NA NA NA NA NA 9249 XM_044307144.1 448 623 272 272 314 NA NA NA NA NA NA 9250 XR_006396302.1 1264 920 533 928 600 Q1PRL4 2.13e-37 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Gallus gallus (Chicken) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 9251 XM_029357435.2 162 159 140 179 337 NA NA NA NA NA NA 9252 XR_006391282.1 368 481 478 303 202 NA NA NA NA NA NA 9253 XM_029333801.2 101 0 0 47 27 Q8T882 1.02e-32 Tauropine dehydrogenase (TaDH) (EC 1.5.1.23) (NAD: tauropine oxidoreductase) Arabella iricolor (Opal worm) NA GO:0050325 9254 XM_029350165.2 0 0 25 60 124 O57525 4.41e-78 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Rana dybowskii (Dybovsky's frog) (Korean brown frog) steroid biosynthetic process [GO:0006694] GO:0004508; GO:0005506; GO:0006694; GO:0016020; GO:0020037; GO:0047442 9255 XR_006396858.1 18 0 11 0 6 NA NA NA NA NA NA 9256 XR_006398155.1 4 21 1 16 4 NA NA NA NA NA NA 9257 XR_006395462.1 12 2 2 12 15 NA NA NA NA NA NA 9258 XR_003824638.2 39 77 45 51 118 NA NA NA NA NA NA 9259 XM_029328725.2 2 4 29 26 23 NA NA NA NA NA NA 9260 XM_029328569.2 0 0 0 68 50 NA NA NA NA NA NA 9261 XM_044323896.1 0 5 0 7 4 NA NA NA NA NA NA 9262 XR_006395818.1 0 12 0 0 0 NA NA NA NA NA NA 9263 XM_044313048.1 52 45 15 76 122 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9264 XM_044313048.1 52 45 15 76 122 Q96AY4 1.53e-151 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9265 XM_044313048.1 52 45 15 76 122 Q96AY4 1.5e-117 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9266 XR_006392618.1 1 3 0 1 9 NA NA NA NA NA NA 9267 XR_006397538.1 49 159 28 83 62 NA NA NA NA NA NA 9268 XM_029348737.2 4067 3836 3468 4183 4656 P15651 0 Short-chain specific acyl-CoA dehydrogenase, mitochondrial (SCAD) (EC 1.3.8.1) (Butyryl-CoA dehydrogenase) Rattus norvegicus (Rat) butyrate catabolic process [GO:0046359]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; response to glucocorticoid [GO:0051384]; response to starvation [GO:0042594] GO:0000062; GO:0003995; GO:0004085; GO:0005739; GO:0005759; GO:0006635; GO:0016937; GO:0031966; GO:0033539; GO:0042594; GO:0042802; GO:0046359; GO:0050660; GO:0051384 9269 XM_044326321.1 146 0 136 64 448 B3EWZ6 2.76e-125 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 9270 XM_044326321.1 146 0 136 64 448 B3EWZ6 1.2e-122 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 9271 XM_044326321.1 146 0 136 64 448 B3EWZ6 2.63e-122 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 9272 XM_044326321.1 146 0 136 64 448 B3EWZ6 1.22e-118 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 9273 XM_044326321.1 146 0 136 64 448 B3EWZ6 3e-112 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 9274 XM_044326321.1 146 0 136 64 448 B3EWZ6 2.38e-110 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 9275 XM_044326321.1 146 0 136 64 448 B3EWZ6 7.11e-108 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 9276 XM_044326321.1 146 0 136 64 448 B3EWZ6 3.16e-106 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 9277 XM_044326321.1 146 0 136 64 448 B3EWZ6 8.46e-96 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 9278 XM_044326321.1 146 0 136 64 448 B3EWZ6 5.71e-93 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 9279 XM_044326321.1 146 0 136 64 448 B3EWZ6 3.51e-80 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 9280 XM_044326321.1 146 0 136 64 448 B3EWZ6 3.81e-79 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 9281 XM_044326321.1 146 0 136 64 448 B3EWZ6 1.05e-74 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 9282 XM_044326321.1 146 0 136 64 448 B3EWZ6 2.1e-74 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 9283 XM_044326321.1 146 0 136 64 448 B3EWZ6 2.01e-73 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 9284 XM_044326321.1 146 0 136 64 448 B3EWZ6 1.41e-70 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 9285 XM_044326321.1 146 0 136 64 448 B3EWZ6 3.41e-70 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 9286 XM_044326321.1 146 0 136 64 448 B3EWZ6 3.82e-63 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 9287 XM_044326321.1 146 0 136 64 448 B3EWZ6 1.68e-62 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 9288 XM_044326321.1 146 0 136 64 448 B3EWZ6 2.6e-46 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 9289 XM_044326321.1 146 0 136 64 448 B3EWZ6 3e-22 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 9290 XR_006395749.1 1 2 2 5 9 NA NA NA NA NA NA 9291 XM_029327346.2 11 7 7 8 17 NA NA NA NA NA NA 9292 XM_044315043.1 0 17 2 0 5 NA NA NA NA NA NA 9293 XM_029325472.2 5 0 0 1 8 NA NA NA NA NA NA 9294 XM_029349248.2 286 0 140 0 254 Q1LY77 2.48e-95 Histone-lysine N-methyltransferase SETD1B-A (EC 2.1.1.354) (SET domain-containing protein 1B-A) Danio rerio (Zebrafish) (Brachydanio rerio) chromatin organization [GO:0006325]; hematopoietic progenitor cell differentiation [GO:0002244]; histone H3-K4 methylation [GO:0051568] GO:0002244; GO:0003723; GO:0005694; GO:0006325; GO:0016607; GO:0042800; GO:0048188; GO:0051568 9295 XM_029349248.2 286 0 140 0 254 Q1LY77 1.03e-31 Histone-lysine N-methyltransferase SETD1B-A (EC 2.1.1.354) (SET domain-containing protein 1B-A) Danio rerio (Zebrafish) (Brachydanio rerio) chromatin organization [GO:0006325]; hematopoietic progenitor cell differentiation [GO:0002244]; histone H3-K4 methylation [GO:0051568] GO:0002244; GO:0003723; GO:0005694; GO:0006325; GO:0016607; GO:0042800; GO:0048188; GO:0051568 9296 XM_029356114.2 7 12 0 21 0 Q98982 3.88e-27 Substance-P receptor (SPR) (NK-1 receptor) (NK-1R) (Tachykinin receptor 1) Lithobates catesbeianus (American bullfrog) (Rana catesbeiana) NA GO:0004995; GO:0005886 9297 XM_044324278.1 18 27 34 32 86 NA NA NA NA NA NA 9298 XM_044315021.1 186 103 78 107 154 NA NA NA NA NA NA 9299 XR_003824415.2 25 0 0 0 0 NA NA NA NA NA NA 9300 XM_029343437.2 0 2 8 0 19 Q8CBH5 1.48e-40 Major facilitator superfamily domain-containing protein 6 (Macrophage MHC class I receptor 2) Mus musculus (Mouse) adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590] GO:0002250; GO:0005886; GO:0016020; GO:0032393; GO:0042288; GO:0042590 9301 XR_006395941.1 36 47 43 14 53 NA NA NA NA NA NA 9302 XM_044326209.1 0 25 10 2 35 NA NA NA NA NA NA 9303 XM_029344979.2 621 453 25 487 297 Q8CIE2 1.97e-139 Zinc finger MIZ domain-containing protein 2 (PIAS-like protein Zimp7) Mus musculus (Mouse) positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0005634; GO:0005654; GO:0005739; GO:0006357; GO:0008270; GO:0030374; GO:0043596; GO:0045944 9304 XM_029341265.2 5 0 0 34 0 O16025 2.53e-46 Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (AOS) (EC 4.2.1.-) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)] Plexaura homomalla (Black sea rod) arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; lipid oxidation [GO:0034440]; oxylipin biosynthetic process [GO:0031408] GO:0005506; GO:0005737; GO:0006633; GO:0009978; GO:0016020; GO:0019369; GO:0020037; GO:0031408; GO:0034440; GO:0047677 9305 XR_006394678.1 4 18 12 5 30 NA NA NA NA NA NA 9306 XR_006397517.1 51 13 37 19 25 NA NA NA NA NA NA 9307 XM_029332848.2 6 4 1 6 5 NA NA NA NA NA NA 9308 XM_044319266.1 158 63 53 286 171 NA NA NA NA NA NA 9309 XM_029340333.2 296 262 165 179 824 Q54H55 1.53e-40 FAD-linked oxidoreductase DDB_G0289697 (EC 1.-.-.-) Dictyostelium discoideum (Social amoeba) NA GO:0016491; GO:0071949 9310 XM_029357086.2 1302 1390 1465 1106 1288 Q8CIB6 1.93e-42 Transmembrane protein 230 Mus musculus (Mouse) synaptic vesicle transport [GO:0048489] GO:0005769; GO:0005770; GO:0005776; GO:0005783; GO:0005802; GO:0008021; GO:0012505; GO:0016020; GO:0048489; GO:0055037 9311 XR_003828586.2 54 0 20 0 0 NA NA NA NA NA NA 9312 XM_029324258.2 0 29 16 38 14 NA NA NA NA NA NA 9313 XM_029340090.2 43 29 23 49 41 Q96AY4 1.23e-45 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9314 XM_029344162.2 45 8 24 59 61 NA NA NA NA NA NA 9315 XM_044325708.1 0 247 146 437 5 Q12789 7.37e-72 General transcription factor 3C polypeptide 1 (TF3C-alpha) (TFIIIC box B-binding subunit) (Transcription factor IIIC 220 kDa subunit) (TFIIIC 220 kDa subunit) (TFIIIC220) (Transcription factor IIIC subunit alpha) Homo sapiens (Human) 5S class rRNA transcription by RNA polymerase III [GO:0042791]; rRNA transcription [GO:0009303]; transcription by RNA polymerase III [GO:0006383]; transcription initiation at RNA polymerase III promoter [GO:0006384]; tRNA transcription [GO:0009304]; tRNA transcription by RNA polymerase III [GO:0042797] GO:0000127; GO:0000995; GO:0003677; GO:0005654; GO:0005730; GO:0006383; GO:0006384; GO:0009303; GO:0009304; GO:0016020; GO:0042791; GO:0042797; GO:1990904 9316 XM_044325708.1 0 247 146 437 5 Q12789 5.74e-45 General transcription factor 3C polypeptide 1 (TF3C-alpha) (TFIIIC box B-binding subunit) (Transcription factor IIIC 220 kDa subunit) (TFIIIC 220 kDa subunit) (TFIIIC220) (Transcription factor IIIC subunit alpha) Homo sapiens (Human) 5S class rRNA transcription by RNA polymerase III [GO:0042791]; rRNA transcription [GO:0009303]; transcription by RNA polymerase III [GO:0006383]; transcription initiation at RNA polymerase III promoter [GO:0006384]; tRNA transcription [GO:0009304]; tRNA transcription by RNA polymerase III [GO:0042797] GO:0000127; GO:0000995; GO:0003677; GO:0005654; GO:0005730; GO:0006383; GO:0006384; GO:0009303; GO:0009304; GO:0016020; GO:0042791; GO:0042797; GO:1990904 9317 XM_029328933.2 0 54 0 0 4 Q8BLA8 1.3e-126 Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Wasabi receptor) Mus musculus (Mouse) calcium ion transmembrane import into cytosol [GO:0097553]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cell surface receptor signaling pathway [GO:0007166]; cellular calcium ion homeostasis [GO:0006874]; cellular response to carbon dioxide [GO:0071244]; cellular response to cold [GO:0070417]; cellular response to heat [GO:0034605]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to organic substance [GO:0071310]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; positive regulation of anion transport [GO:1903793]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of sensory perception of pain [GO:1904058]; protein homotetramerization [GO:0051289]; regulation of blood circulation [GO:1903522]; regulation of neuronal action potential [GO:0098908]; response to cold [GO:0009409]; response to hydrogen peroxide [GO:0042542]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; sensory perception of pain [GO:0019233]; thermoception [GO:0050955]; urinary bladder smooth muscle contraction [GO:0014832] GO:0005216; GO:0005245; GO:0005262; GO:0005886; GO:0006816; GO:0006874; GO:0007166; GO:0009409; GO:0009410; GO:0010033; GO:0014070; GO:0014832; GO:0015267; GO:0015278; GO:0016020; GO:0016324; GO:0019233; GO:0030424; GO:0032421; GO:0034605; GO:0035774; GO:0042542; GO:0042802; GO:0048265; GO:0050955; GO:0050966; GO:0050968; GO:0050974; GO:0051289; GO:0070301; GO:0070417; GO:0070588; GO:0071244; GO:0071310; GO:0097553; GO:0097604; GO:0098908; GO:1903522; GO:1903793; GO:1904058; GO:1990760 9318 XR_006391753.1 21 39 70 49 99 NA NA NA NA NA NA 9319 XM_044325888.1 69 18 36 64 19 Q9VKA4 6.5e-68 Probable G-protein coupled receptor CG31760 Drosophila melanogaster (Fruit fly) NA GO:0004930; GO:0005886 9320 XM_029323643.2 1430 1338 1030 1491 1252 Q5XHC1 4.5e-99 UPF0602 protein C4orf47 homolog Xenopus laevis (African clawed frog) NA GO:0005737; GO:0005813 9321 XM_044321134.1 454 227 287 259 773 NA NA NA NA NA NA 9322 XM_044311649.1 1752 1513 1684 2718 519 Q8R151 0 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 9323 XM_044311649.1 1752 1513 1684 2718 519 Q8R151 3.26e-115 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 9324 XM_044318937.1 381 7 121 34 327 NA NA NA NA NA NA 9325 XM_044314303.1 113 100 112 171 193 O08912 7.22e-158 Polypeptide N-acetylgalactosaminyltransferase 1 (EC 2.4.1.41) (Polypeptide GalNAc transferase 1) (GalNAc-T1) (pp-GaNTase 1) (Protein-UDP acetylgalactosaminyltransferase 1) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 1) [Cleaved into: Polypeptide N-acetylgalactosaminyltransferase 1 soluble form] Mus musculus (Mouse) protein O-linked glycosylation [GO:0006493]; protein O-linked glycosylation via serine [GO:0018242]; protein O-linked glycosylation via threonine [GO:0018243] GO:0004653; GO:0005576; GO:0005794; GO:0006493; GO:0018242; GO:0018243; GO:0030145; GO:0030246; GO:0032580; GO:0048471 9326 XR_003824288.2 8 0 15 0 6 NA NA NA NA NA NA 9327 XM_044314814.1 68 36 46 0 172 NA NA NA NA NA NA 9328 XR_006393622.1 140 701 209 176 440 NA NA NA NA NA NA 9329 XR_006397387.1 0 0 0 0 15 NA NA NA NA NA NA 9330 XM_029355928.2 147 59 111 106 207 NA NA NA NA NA NA 9331 XM_044307076.1 0 38 467 121 0 Q9BUD6 6.21e-32 Spondin-2 (Differentially expressed in cancerous and non-cancerous lung cells 1) (DIL-1) (Mindin) Homo sapiens (Human) cell adhesion [GO:0007155]; cellular response to lipopolysaccharide [GO:0071222]; defense response to fungus [GO:0050832]; defense response to virus [GO:0051607]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; mast cell mediated immunity [GO:0002448]; opsonization [GO:0008228]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of tumor necrosis factor production [GO:0032760] GO:0001530; GO:0002448; GO:0003823; GO:0007155; GO:0008228; GO:0031012; GO:0032755; GO:0032760; GO:0043152; GO:0045087; GO:0046872; GO:0050832; GO:0051607; GO:0060907; GO:0070062; GO:0071222 9332 XM_044307076.1 0 38 467 121 0 Q9BUD6 5.02e-22 Spondin-2 (Differentially expressed in cancerous and non-cancerous lung cells 1) (DIL-1) (Mindin) Homo sapiens (Human) cell adhesion [GO:0007155]; cellular response to lipopolysaccharide [GO:0071222]; defense response to fungus [GO:0050832]; defense response to virus [GO:0051607]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; mast cell mediated immunity [GO:0002448]; opsonization [GO:0008228]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of tumor necrosis factor production [GO:0032760] GO:0001530; GO:0002448; GO:0003823; GO:0007155; GO:0008228; GO:0031012; GO:0032755; GO:0032760; GO:0043152; GO:0045087; GO:0046872; GO:0050832; GO:0051607; GO:0060907; GO:0070062; GO:0071222 9333 XM_029346944.2 8 13 4 16 0 Q22875 6.15e-41 Leucine-rich repeat protein soc-2 (Suppressor of Clr protein 2) (Suppressor of activated let-60 Ras protein 8) Caenorhabditis elegans fibroblast growth factor receptor signaling pathway [GO:0008543]; muscle organ development [GO:0007517]; positive regulation of Ras protein signal transduction [GO:0046579]; regulation of cell projection organization [GO:0031344]; signal transduction [GO:0007165]; vulval development [GO:0040025] GO:0007165; GO:0007517; GO:0008543; GO:0031267; GO:0031344; GO:0040025; GO:0046579 9334 XM_044322896.1 168 44 93 0 102 NA NA NA NA NA NA 9335 XM_029340257.2 118 93 119 0 237 NA NA NA NA NA NA 9336 XR_006394568.1 0 92 25 31 56 Q9R1S3 6.86e-28 GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N) Mus musculus (Mouse) GPI anchor biosynthetic process [GO:0006506] GO:0005789; GO:0005829; GO:0005886; GO:0006506; GO:0016780; GO:0051377 9337 XR_006394568.1 0 92 25 31 56 Q9R1S3 6.86e-28 GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N) Mus musculus (Mouse) GPI anchor biosynthetic process [GO:0006506] GO:0005789; GO:0005829; GO:0005886; GO:0006506; GO:0016780; GO:0051377 9338 XM_044328213.1 18 0 0 0 0 NA NA NA NA NA NA 9339 XR_006395345.1 31 5 25 39 133 NA NA NA NA NA NA 9340 XM_029350365.2 0 24 0 37 0 NA NA NA NA NA NA 9341 XM_044327858.1 141 75 122 125 132 P20905 6.4e-23 5-hydroxytryptamine receptor 1 (5-HT receptor) (5HT-dro) (Serotonin receptor 1) Drosophila melanogaster (Fruit fly) adenylate cyclase-activating serotonin receptor signaling pathway [GO:0007192]; chemical synaptic transmission [GO:0007268]; courtship behavior [GO:0007619]; female mating behavior [GO:0060180]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; male courtship behavior, orientation prior to leg tapping and wing vibration [GO:0016543]; male courtship behavior, proboscis-mediated licking [GO:0016546]; male courtship behavior, veined wing vibration [GO:0016545]; male mating behavior [GO:0060179]; serotonin receptor signaling pathway [GO:0007210] GO:0004993; GO:0005886; GO:0007187; GO:0007192; GO:0007210; GO:0007268; GO:0007619; GO:0008227; GO:0016020; GO:0016543; GO:0016545; GO:0016546; GO:0030425; GO:0030594; GO:0045202; GO:0060179; GO:0060180 9342 XM_044324509.1 394 110 302 161 244 Q7Z4T9 0 Cilia- and flagella-associated protein 91 (CFAP91) (AMY-1-associating protein expressed in testis 1) (AAT-1) (MYCBP/AMY-1-associated testis-expressed protein 1) (Protein MAATS1) Homo sapiens (Human) axonemal central apparatus assembly [GO:1904158]; cell differentiation [GO:0030154]; cilium movement [GO:0003341]; spermatogenesis [GO:0007283] GO:0003341; GO:0005739; GO:0005930; GO:0007283; GO:0030154; GO:0031514; GO:1904158 9343 XM_029337879.2 0 7 4 8 17 NA NA NA NA NA NA 9344 XM_029351586.2 1461 1060 778 1301 1832 O88451 1.67e-72 Retinol dehydrogenase 7 (EC 1.1.1.105) (Cis-retinol/3alpha-hydroxysterol short-chain dehydrogenase isozyme 2) (Cis-retinol/androgen dehydrogenase type 2) (CRAD-2) Mus musculus (Mouse) retinol metabolic process [GO:0042572]; steroid metabolic process [GO:0008202] GO:0003824; GO:0004745; GO:0005783; GO:0008202; GO:0016491; GO:0042572; GO:0043231; GO:0047023; GO:0047044 9345 XM_044310449.1 13 2 10 12 3 NA NA NA NA NA NA 9346 XM_029351744.2 45 1530 75 366 266 NA NA NA NA NA NA 9347 XM_029334982.2 419 103 233 296 254 Q00808 1.79e-29 Vegetative incompatibility protein HET-E-1 Podospora anserina (Pleurage anserina) NA GO:0005525 9348 XM_029334982.2 419 103 233 296 254 Q00808 1.73e-26 Vegetative incompatibility protein HET-E-1 Podospora anserina (Pleurage anserina) NA GO:0005525 9349 XM_029334982.2 419 103 233 296 254 Q00808 4.93e-25 Vegetative incompatibility protein HET-E-1 Podospora anserina (Pleurage anserina) NA GO:0005525 9350 XM_029334982.2 419 103 233 296 254 Q00808 3.29e-22 Vegetative incompatibility protein HET-E-1 Podospora anserina (Pleurage anserina) NA GO:0005525 9351 XM_029338634.2 1965 1889 1249 1268 789 NA NA NA NA NA NA 9352 XM_044310459.1 1206 384 193 1334 393 NA NA NA NA NA NA 9353 XM_044313951.1 33 13 2 20 39 NA NA NA NA NA NA 9354 XM_029338354.2 6 3 5 5 1 NA NA NA NA NA NA 9355 XM_044310188.1 9 0 38 8 43 NA NA NA NA NA NA 9356 XM_044318187.1 23 17 13 22 0 NA NA NA NA NA NA 9357 XM_029349774.2 895 1540 1708 1018 2243 NA NA NA NA NA NA 9358 XR_006397913.1 27 3 5 10 10 NA NA NA NA NA NA 9359 XM_044310568.1 0 0 2 0 10 NA NA NA NA NA NA 9360 XM_044317525.1 152 23 83 29 87 NA NA NA NA NA NA 9361 XM_044314844.1 2 0 0 7 1 NA NA NA NA NA NA 9362 XM_044317206.1 552 331 258 586 574 Q921G8 0 Gamma-tubulin complex component 2 (GCP-2) Mus musculus (Mouse) brain development [GO:0007420]; cytoplasmic microtubule organization [GO:0031122]; meiotic cell cycle [GO:0051321]; microtubule nucleation [GO:0007020]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; spindle assembly [GO:0051225] GO:0000278; GO:0000922; GO:0000923; GO:0000930; GO:0001764; GO:0005654; GO:0005813; GO:0005815; GO:0005829; GO:0005874; GO:0007020; GO:0007420; GO:0008275; GO:0031122; GO:0043015; GO:0051225; GO:0051321 9363 XM_044317281.1 2247 1970 963 1797 1825 Q6Y685 1.32e-43 Transforming acidic coiled-coil-containing protein 1 Mus musculus (Mouse) cell division [GO:0051301]; cell population proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; interkinetic nuclear migration [GO:0022027]; microtubule cytoskeleton organization [GO:0000226]; mitotic spindle organization [GO:0007052]; neurogenesis [GO:0022008]; regulation of microtubule-based process [GO:0032886] GO:0000226; GO:0005634; GO:0005737; GO:0005815; GO:0005829; GO:0007052; GO:0008283; GO:0016922; GO:0019904; GO:0021987; GO:0022008; GO:0022027; GO:0030331; GO:0030374; GO:0030496; GO:0032886; GO:0035259; GO:0042974; GO:0042975; GO:0046965; GO:0046966; GO:0051301 9364 XM_029333009.2 11 7 0 0 10 NA NA NA NA NA NA 9365 XM_044319342.1 0 3 8 0 1 P30974 8.72e-33 Tachykinin-like peptides receptor 86C (NKD) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; inter-male aggressive behavior [GO:0002121]; neuropeptide signaling pathway [GO:0007218]; tachykinin receptor signaling pathway [GO:0007217] GO:0002121; GO:0004995; GO:0005886; GO:0007186; GO:0007217; GO:0007218; GO:0008188; GO:0016020 9366 XM_029323983.2 5585 5060 2372 2134 2339 Q27433 1.58e-119 Mechanosensory protein 2 Caenorhabditis elegans detection of mechanical stimulus involved in sensory perception of touch [GO:0050976]; mechanosensory behavior [GO:0007638]; positive regulation of detection of mechanical stimulus involved in sensory perception of touch [GO:1905789]; positive regulation of mechanosensory behavior [GO:1905792]; potassium ion transport [GO:0006813]; response to mechanical stimulus [GO:0009612] GO:0005272; GO:0005886; GO:0006813; GO:0007638; GO:0009612; GO:0015485; GO:0032589; GO:0043005; GO:0050976; GO:1905789; GO:1905792 9367 XM_029345170.2 15 0 6 15 71 Q3SZV5 7.68e-33 Proteasome maturation protein (Proteassemblin) Bos taurus (Bovine) proteasome assembly [GO:0043248] GO:0005634; GO:0005737; GO:0005783; GO:0005829; GO:0016020; GO:0043248 9368 XR_006394245.1 28 0 21 35 0 NA NA NA NA NA NA 9369 XM_029332978.2 22 0 124 77 0 Q9H0B8 5.54e-31 Cysteine-rich secretory protein LCCL domain-containing 2 (Cysteine-rich secretory protein 11) (CRISP-11) (LCCL domain-containing cysteine-rich secretory protein 2) Homo sapiens (Human) extracellular matrix organization [GO:0030198]; face morphogenesis [GO:0060325]; lung development [GO:0030324] GO:0005539; GO:0005576; GO:0005615; GO:0008201; GO:0030133; GO:0030198; GO:0030324; GO:0031012; GO:0034774; GO:0060325; GO:0070062; GO:1904813 9370 XM_029351474.2 208 308 290 286 357 NA NA NA NA NA NA 9371 XM_029352381.2 6 8 0 9 32 NA NA NA NA NA NA 9372 XR_006394525.1 3585 2986 1889 3091 2494 NA NA NA NA NA NA 9373 XR_006395215.1 34 46 0 0 0 NA NA NA NA NA NA 9374 XR_006393234.1 40 210 182 216 172 NA NA NA NA NA NA 9375 XM_029338528.2 590 682 460 472 493 NA NA NA NA NA NA 9376 XM_029357218.2 1277 1399 739 1726 1795 P49288 5.1e-24 Melatonin receptor type 1C (Mel-1C-R) (Mel1c receptor) (CKB) Gallus gallus (Chicken) G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of glucose import [GO:0046325]; negative regulation of glycolytic process [GO:0045820] GO:0004930; GO:0005654; GO:0005886; GO:0007186; GO:0008502; GO:0045820; GO:0046325; GO:1904408 9377 XM_029341280.2 2542 1665 1549 3316 1429 NA NA NA NA NA NA 9378 XR_006394490.1 21 3 0 5 5 NA NA NA NA NA NA 9379 XR_006396874.1 2 2 3 1 25 NA NA NA NA NA NA 9380 XM_044308308.1 230 569 630 575 461 Q54PI5 8.51e-41 Probable gluconokinase (EC 2.7.1.12) (Gluconate kinase) Dictyostelium discoideum (Social amoeba) D-gluconate catabolic process [GO:0046177]; phosphorylation [GO:0016310] GO:0005524; GO:0016310; GO:0046177; GO:0046316 9381 XM_029358373.2 37 2 35 32 39 Q7Z402 1.67e-86 Transmembrane channel-like protein 7 Homo sapiens (Human) NA GO:0005886; GO:0008381 9382 XM_044313789.1 24 18 33 43 46 B1AVY7 2.7e-69 Kinesin-like protein KIF16B Mus musculus (Mouse) cellular response to type II interferon [GO:0071346]; early endosome to late endosome transport [GO:0045022]; endoderm development [GO:0007492]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; formation of primary germ layer [GO:0001704]; Golgi to endosome transport [GO:0006895]; microtubule-based movement [GO:0007018]; receptor catabolic process [GO:0032801]; regulation of receptor recycling [GO:0001919] GO:0001704; GO:0001919; GO:0003777; GO:0005524; GO:0005547; GO:0005737; GO:0005768; GO:0005769; GO:0005819; GO:0005829; GO:0005871; GO:0005874; GO:0006895; GO:0007018; GO:0007173; GO:0007492; GO:0008017; GO:0008543; GO:0008574; GO:0016887; GO:0031267; GO:0031901; GO:0032266; GO:0032801; GO:0043325; GO:0045022; GO:0045335; GO:0071346; GO:0080025 9383 XM_044316183.1 449 285 294 434 448 Q69CM7 2.4e-99 MYCBP-associated protein (Organ of Corti membrane-associated protein of 106 kDa) Rattus norvegicus (Rat) cell differentiation [GO:0030154]; chemical synaptic transmission [GO:0007268]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283] GO:0005737; GO:0007268; GO:0007283; GO:0007605; GO:0019897; GO:0030154 9384 XM_044313601.1 1242 709 1291 1092 1176 Q7ZXY0 0 Inositol-3-phosphate synthase 1-A (IPS 1-A) (EC 5.5.1.4) (Myo-inositol 1-phosphate synthase A) (MI-1-P synthase A) (MIP synthase A) Xenopus laevis (African clawed frog) inositol biosynthetic process [GO:0006021]; phospholipid biosynthetic process [GO:0008654] GO:0004512; GO:0005737; GO:0006021; GO:0008654 9385 XM_044311358.1 17 0 6 9 0 Q7Z4T9 1.84e-31 Cilia- and flagella-associated protein 91 (CFAP91) (AMY-1-associating protein expressed in testis 1) (AAT-1) (MYCBP/AMY-1-associated testis-expressed protein 1) (Protein MAATS1) Homo sapiens (Human) axonemal central apparatus assembly [GO:1904158]; cell differentiation [GO:0030154]; cilium movement [GO:0003341]; spermatogenesis [GO:0007283] GO:0003341; GO:0005739; GO:0005930; GO:0007283; GO:0030154; GO:0031514; GO:1904158 9386 XR_006396569.1 131 84 69 154 114 NA NA NA NA NA NA 9387 XM_029329960.2 23 0 2 43 0 NA NA NA NA NA NA 9388 XM_044324995.1 48 16 14 39 25 Q96AY4 3.92e-66 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9389 XM_044324995.1 48 16 14 39 25 Q96AY4 4.81e-60 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9390 XM_044324995.1 48 16 14 39 25 Q96AY4 2.61e-58 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9391 XM_044324995.1 48 16 14 39 25 Q96AY4 1.36e-57 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9392 XM_044324995.1 48 16 14 39 25 Q96AY4 5.34e-55 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9393 XM_044324995.1 48 16 14 39 25 Q96AY4 1.61e-51 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9394 XM_044324995.1 48 16 14 39 25 Q96AY4 1.68e-49 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9395 XM_044324995.1 48 16 14 39 25 Q96AY4 3.94e-48 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9396 XM_044324995.1 48 16 14 39 25 Q96AY4 2.81e-47 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9397 XM_044324995.1 48 16 14 39 25 Q96AY4 5.99e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9398 XM_044324995.1 48 16 14 39 25 Q96AY4 4.1e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9399 XR_003826126.2 27 21 40 15 24 NA NA NA NA NA NA 9400 XM_044308336.1 14 20 8 11 7 Q6LAF1 3.25e-52 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 9401 XR_003827024.2 3 10 2 31 2 NA NA NA NA NA NA 9402 XM_044322022.1 1359 1069 807 1330 1499 A7SD85 0 Cell division cycle 5-related protein (Cdc5-like protein) Nematostella vectensis (Starlet sea anemone) cell cycle [GO:0007049]; DNA repair [GO:0006281]; mRNA splicing, via spliceosome [GO:0000398]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000398; GO:0000974; GO:0000977; GO:0000981; GO:0003723; GO:0005681; GO:0005737; GO:0006281; GO:0006357; GO:0007049 9403 XM_029349680.2 392 403 299 953 1149 Q03364 1.84e-92 Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) Xenopus laevis (African clawed frog) apoptotic process [GO:0006915]; positive regulation of cell population proliferation [GO:0008284] GO:0005007; GO:0005524; GO:0005794; GO:0005886; GO:0006915; GO:0008284; GO:0031410 9404 XM_044311114.1 22 4 21 47 9 Q09575 1.48e-40 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 9405 XM_044322314.1 551 568 281 596 461 NA NA NA NA NA NA 9406 XR_003825855.2 5652 2827 187 1928 884 NA NA NA NA NA NA 9407 XM_044310418.1 5 0 5 16 0 NA NA NA NA NA NA 9408 XM_044312974.1 183 115 271 192 260 NA NA NA NA NA NA 9409 XR_003825121.2 68 169 81 132 97 NA NA NA NA NA NA 9410 XM_044308604.1 589 271 312 294 331 Q96AY4 2.88e-108 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9411 XM_044308604.1 589 271 312 294 331 Q96AY4 6.48e-108 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9412 XM_044308604.1 589 271 312 294 331 Q96AY4 4.17e-107 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9413 XM_044308604.1 589 271 312 294 331 Q96AY4 1.59e-103 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9414 XM_044308604.1 589 271 312 294 331 Q96AY4 4.71e-98 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9415 XM_044308604.1 589 271 312 294 331 Q96AY4 4.78e-93 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9416 XM_044314730.1 383 211 0 0 0 Q7RTR2 1.3e-68 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 9417 XM_044314730.1 383 211 0 0 0 Q7RTR2 1.76e-68 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 9418 XM_044314730.1 383 211 0 0 0 Q7RTR2 2.21e-56 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 9419 XM_044314730.1 383 211 0 0 0 Q7RTR2 2.24e-43 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 9420 XR_006394874.1 1 6 0 0 0 NA NA NA NA NA NA 9421 XM_044317733.1 743 357 356 850 489 Q00968 9.95e-78 Pro-epidermal growth factor (EGF) [Cleaved into: Epidermal growth factor] Sus scrofa (Pig) epidermal growth factor receptor signaling pathway via MAPK cascade [GO:0038029]; positive regulation of DNA binding [GO:0043388]; positive regulation of DNA replication [GO:0045740]; regulation of receptor signaling pathway via JAK-STAT [GO:0046425] GO:0005509; GO:0005886; GO:0008083; GO:0038029; GO:0043388; GO:0045740; GO:0046425 9422 XM_044317733.1 743 357 356 850 489 Q00968 4.96e-42 Pro-epidermal growth factor (EGF) [Cleaved into: Epidermal growth factor] Sus scrofa (Pig) epidermal growth factor receptor signaling pathway via MAPK cascade [GO:0038029]; positive regulation of DNA binding [GO:0043388]; positive regulation of DNA replication [GO:0045740]; regulation of receptor signaling pathway via JAK-STAT [GO:0046425] GO:0005509; GO:0005886; GO:0008083; GO:0038029; GO:0043388; GO:0045740; GO:0046425 9423 XR_006391456.1 20 0 0 0 3 NA NA NA NA NA NA 9424 XR_006391731.1 121 155 84 72 152 Q5RHH4 0 Intraflagellar transport protein 172 homolog Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; intraciliary transport [GO:0042073]; photoreceptor cell maintenance [GO:0045494]; pronephros development [GO:0048793]; regulation of TOR signaling [GO:0032006]; retina development in camera-type eye [GO:0060041] GO:0005929; GO:0005930; GO:0030992; GO:0032006; GO:0036064; GO:0042073; GO:0045494; GO:0048793; GO:0060041; GO:0060271 9425 XR_006391731.1 121 155 84 72 152 Q5RHH4 0 Intraflagellar transport protein 172 homolog Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; intraciliary transport [GO:0042073]; photoreceptor cell maintenance [GO:0045494]; pronephros development [GO:0048793]; regulation of TOR signaling [GO:0032006]; retina development in camera-type eye [GO:0060041] GO:0005929; GO:0005930; GO:0030992; GO:0032006; GO:0036064; GO:0042073; GO:0045494; GO:0048793; GO:0060041; GO:0060271 9426 XR_006391731.1 121 155 84 72 152 Q5RHH4 3.88e-102 Intraflagellar transport protein 172 homolog Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; intraciliary transport [GO:0042073]; photoreceptor cell maintenance [GO:0045494]; pronephros development [GO:0048793]; regulation of TOR signaling [GO:0032006]; retina development in camera-type eye [GO:0060041] GO:0005929; GO:0005930; GO:0030992; GO:0032006; GO:0036064; GO:0042073; GO:0045494; GO:0048793; GO:0060041; GO:0060271 9427 XR_006391731.1 121 155 84 72 152 Q5RHH4 3.88e-102 Intraflagellar transport protein 172 homolog Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; intraciliary transport [GO:0042073]; photoreceptor cell maintenance [GO:0045494]; pronephros development [GO:0048793]; regulation of TOR signaling [GO:0032006]; retina development in camera-type eye [GO:0060041] GO:0005929; GO:0005930; GO:0030992; GO:0032006; GO:0036064; GO:0042073; GO:0045494; GO:0048793; GO:0060041; GO:0060271 9428 XR_006391731.1 121 155 84 72 152 Q5RHH4 3.88e-102 Intraflagellar transport protein 172 homolog Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; intraciliary transport [GO:0042073]; photoreceptor cell maintenance [GO:0045494]; pronephros development [GO:0048793]; regulation of TOR signaling [GO:0032006]; retina development in camera-type eye [GO:0060041] GO:0005929; GO:0005930; GO:0030992; GO:0032006; GO:0036064; GO:0042073; GO:0045494; GO:0048793; GO:0060041; GO:0060271 9429 XR_006391731.1 121 155 84 72 152 Q5RHH4 2.72e-91 Intraflagellar transport protein 172 homolog Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; intraciliary transport [GO:0042073]; photoreceptor cell maintenance [GO:0045494]; pronephros development [GO:0048793]; regulation of TOR signaling [GO:0032006]; retina development in camera-type eye [GO:0060041] GO:0005929; GO:0005930; GO:0030992; GO:0032006; GO:0036064; GO:0042073; GO:0045494; GO:0048793; GO:0060041; GO:0060271 9430 XR_006391731.1 121 155 84 72 152 Q5RHH4 2.72e-91 Intraflagellar transport protein 172 homolog Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; intraciliary transport [GO:0042073]; photoreceptor cell maintenance [GO:0045494]; pronephros development [GO:0048793]; regulation of TOR signaling [GO:0032006]; retina development in camera-type eye [GO:0060041] GO:0005929; GO:0005930; GO:0030992; GO:0032006; GO:0036064; GO:0042073; GO:0045494; GO:0048793; GO:0060041; GO:0060271 9431 XM_044324752.1 548 735 350 1441 1032 Q9SSA4 3.34e-26 NA NA NA NA 9432 XM_029355527.2 647 149 231 461 698 Q7ZWE3 3.57e-66 La-related protein 7 (La ribonucleoprotein domain family member 7) Danio rerio (Zebrafish) (Brachydanio rerio) box C/D RNA 3'-end processing [GO:0000494]; cardiac muscle tissue regeneration [GO:0061026]; cell differentiation [GO:0030154]; mRNA processing [GO:0006397]; positive regulation of protein localization to Cajal body [GO:1904871]; positive regulation of snRNA transcription by RNA polymerase II [GO:1905382]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of mRNA splicing, via spliceosome [GO:0048024]; RNA splicing [GO:0008380]; spermatogenesis [GO:0007283]; U6 2'-O-snRNA methylation [GO:1990438] GO:0000494; GO:0003723; GO:0005634; GO:0005654; GO:0006397; GO:0007283; GO:0008380; GO:0017070; GO:0030154; GO:0030532; GO:0048024; GO:0060043; GO:0061026; GO:0097322; GO:1904871; GO:1905382; GO:1990438; GO:1990904 9433 XM_044311439.1 1 0 74 61 5 NA NA NA NA NA NA 9434 XM_044307251.1 434 199 186 370 361 Q99807 9.43e-54 5-demethoxyubiquinone hydroxylase, mitochondrial (DMQ hydroxylase) (EC 1.14.99.60) (Timing protein clk-1 homolog) (Ubiquinone biosynthesis monooxygenase COQ7) Homo sapiens (Human) determination of adult lifespan [GO:0008340]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression [GO:0010468]; regulation of reactive oxygen species metabolic process [GO:2000377]; ubiquinone biosynthetic process [GO:0006744] GO:0000122; GO:0003682; GO:0005634; GO:0005694; GO:0005739; GO:0005743; GO:0006744; GO:0008340; GO:0008682; GO:0010468; GO:0016709; GO:0031314; GO:0045944; GO:0046872; GO:0110142; GO:2000377 9435 XM_044320893.1 5 4 10 9 14 NA NA NA NA NA NA 9436 XM_029346138.2 3192 2098 2187 4982 4174 Q6GNV7 9.04e-39 Solute carrier family 49 member 4 homolog (Disrupted in renal carcinoma protein 2 homolog) Xenopus laevis (African clawed frog) NA GO:0005765; GO:0022857 9437 XM_029346138.2 3192 2098 2187 4982 4174 Q6GNV7 2.44e-23 Solute carrier family 49 member 4 homolog (Disrupted in renal carcinoma protein 2 homolog) Xenopus laevis (African clawed frog) NA GO:0005765; GO:0022857 9438 XM_029358707.2 793 360 368 587 449 Q5U374 9.43e-104 Kelch-like protein 12 Danio rerio (Zebrafish) (Brachydanio rerio) anterior/posterior pattern specification [GO:0009952]; convergent extension involved in axis elongation [GO:0060028]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; protein monoubiquitination [GO:0006513]; Wnt signaling pathway [GO:0016055] GO:0006513; GO:0006888; GO:0009952; GO:0014029; GO:0014032; GO:0016055; GO:0030127; GO:0030134; GO:0031463; GO:0048208; GO:0060028 9439 XM_044309370.1 0 31 33 75 0 NA NA NA NA NA NA 9440 XM_029346490.2 233 149 69 176 177 Q9UKP4 0 A disintegrin and metalloproteinase with thrombospondin motifs 7 (ADAM-TS 7) (ADAM-TS7) (ADAMTS-7) (EC 3.4.24.-) (COMPase) Homo sapiens (Human) cellular response to BMP stimulus [GO:0071773]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; chondrocyte differentiation [GO:0002062]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; negative regulation of chondrocyte differentiation [GO:0032331]; ossification involved in bone maturation [GO:0043931]; proteoglycan metabolic process [GO:0006029]; proteolysis involved in protein catabolic process [GO:0051603] GO:0002062; GO:0004222; GO:0005576; GO:0005788; GO:0006029; GO:0008237; GO:0009986; GO:0030198; GO:0030199; GO:0031012; GO:0032331; GO:0043931; GO:0046872; GO:0051603; GO:0071347; GO:0071356; GO:0071773 9441 XM_029346490.2 233 149 69 176 177 Q9UKP4 1.08e-25 A disintegrin and metalloproteinase with thrombospondin motifs 7 (ADAM-TS 7) (ADAM-TS7) (ADAMTS-7) (EC 3.4.24.-) (COMPase) Homo sapiens (Human) cellular response to BMP stimulus [GO:0071773]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; chondrocyte differentiation [GO:0002062]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; negative regulation of chondrocyte differentiation [GO:0032331]; ossification involved in bone maturation [GO:0043931]; proteoglycan metabolic process [GO:0006029]; proteolysis involved in protein catabolic process [GO:0051603] GO:0002062; GO:0004222; GO:0005576; GO:0005788; GO:0006029; GO:0008237; GO:0009986; GO:0030198; GO:0030199; GO:0031012; GO:0032331; GO:0043931; GO:0046872; GO:0051603; GO:0071347; GO:0071356; GO:0071773 9442 XM_044311080.1 20 4 0 20 24 NA NA NA NA NA NA 9443 XM_029335508.2 1146 621 594 987 1054 G3X9Z4 5.13e-38 NA NA NA NA 9444 XM_029335508.2 1146 621 594 987 1054 G3X9Z4 1.22e-33 NA NA NA NA 9445 XM_044327899.1 0 10 0 0 0 NA NA NA NA NA NA 9446 XM_029342533.2 317 304 182 312 360 Q9DC33 1.8e-85 High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein HMGX1) (Inhibitor of BRAF35) (iBRAF) Mus musculus (Mouse) chromatin organization [GO:0006325]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of gene expression [GO:0010468] GO:0000122; GO:0003677; GO:0005634; GO:0006325; GO:0010468; GO:0033234; GO:0042802; GO:0045665 9447 XM_044315910.1 0 2 9 3 18 NA NA NA NA NA NA 9448 XM_029324142.2 517 345 281 353 480 Q64LD2 2.43e-85 WD repeat-containing protein 25 Homo sapiens (Human) NA NA 9449 XM_029333083.2 5 82 61 31 11 NA NA NA NA NA NA 9450 XM_044324979.1 5 6 1 0 3 Q80XJ3 1.37e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 9451 XM_044324979.1 5 6 1 0 3 Q80XJ3 1.51e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 9452 XM_044324979.1 5 6 1 0 3 Q80XJ3 5.32e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 9453 XM_044324979.1 5 6 1 0 3 Q80XJ3 2.88e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 9454 XM_044324979.1 5 6 1 0 3 Q80XJ3 7.3e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 9455 XM_044324979.1 5 6 1 0 3 Q80XJ3 4.73e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 9456 XM_044324979.1 5 6 1 0 3 Q80XJ3 1.24e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 9457 XM_044324979.1 5 6 1 0 3 Q80XJ3 2.78e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 9458 XM_044324979.1 5 6 1 0 3 Q80XJ3 6.84e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 9459 XM_044312127.1 8 0 2 0 1 NA NA NA NA NA NA 9460 XR_006393775.1 29 34 56 30 35 NA NA NA NA NA NA 9461 XM_044311935.1 17 25 32 103 61 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9462 XM_044311935.1 17 25 32 103 61 Q96AY4 4.4e-163 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9463 XM_044311935.1 17 25 32 103 61 Q96AY4 1.74e-106 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9464 XM_044311935.1 17 25 32 103 61 Q96AY4 2.01e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9465 XM_029336815.2 928 474 358 1314 625 Q9UKP5 2.77e-123 A disintegrin and metalloproteinase with thrombospondin motifs 6 (ADAM-TS 6) (ADAM-TS6) (ADAMTS-6) (EC 3.4.24.-) Homo sapiens (Human) aorta development [GO:0035904]; cardiac septum development [GO:0003279]; coronary vasculature development [GO:0060976]; extracellular matrix organization [GO:0030198]; kidney development [GO:0001822]; proteolysis [GO:0006508] GO:0001822; GO:0003279; GO:0004222; GO:0005576; GO:0006508; GO:0008237; GO:0030198; GO:0031012; GO:0035904; GO:0046872; GO:0060976 9466 XM_044316896.1 0 0 0 24 40 P16610 2.27e-32 Substance-K receptor (SKR) (NK-2 receptor) (NK-2R) (Neurokinin A receptor) (Tachykinin receptor 2) Rattus norvegicus (Rat) intestine smooth muscle contraction [GO:0014827]; negative regulation of luteinizing hormone secretion [GO:0033685]; operant conditioning [GO:0035106]; positive regulation of acetylcholine secretion, neurotransmission [GO:0014057]; positive regulation of flagellated sperm motility [GO:1902093]; positive regulation of ion transport [GO:0043270]; positive regulation of uterine smooth muscle contraction [GO:0070474]; positive regulation of vascular permeability [GO:0043117]; prolactin secretion [GO:0070459]; regulation of uterine smooth muscle contraction [GO:0070472]; response to electrical stimulus [GO:0051602] GO:0004995; GO:0005886; GO:0014057; GO:0014827; GO:0016020; GO:0016497; GO:0033685; GO:0035106; GO:0036126; GO:0043117; GO:0043270; GO:0051602; GO:0061827; GO:0070459; GO:0070472; GO:0070474; GO:0097225; GO:1902093 9467 XM_029324641.2 11 22 11 13 6 Q6GNS1 3.7e-30 Carbohydrate sulfotransferase 10 (EC 2.8.2.-) (HNK-1 sulfotransferase) (HNK-1ST) (HNK1ST) Xenopus laevis (African clawed frog) carbohydrate biosynthetic process [GO:0016051] GO:0000139; GO:0008146; GO:0016051 9468 XR_003824726.2 1166 1249 864 1221 1056 NA NA NA NA NA NA 9469 XR_006394668.1 43 19 21 36 61 Q9P2E2 2.02e-151 Kinesin-like protein KIF17 (KIF3-related motor protein) Homo sapiens (Human) anterograde dendritic transport of neurotransmitter receptor complex [GO:0098971]; cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] GO:0001750; GO:0001917; GO:0003777; GO:0005524; GO:0005815; GO:0005829; GO:0005871; GO:0005874; GO:0005929; GO:0005930; GO:0007018; GO:0008017; GO:0008574; GO:0015031; GO:0016192; GO:0016887; GO:0030030; GO:0032391; GO:0032839; GO:0036064; GO:0043005; GO:0098971; GO:1990075 9470 XM_029334593.2 0 0 0 0 76 Q9UKP5 2.05e-123 A disintegrin and metalloproteinase with thrombospondin motifs 6 (ADAM-TS 6) (ADAM-TS6) (ADAMTS-6) (EC 3.4.24.-) Homo sapiens (Human) aorta development [GO:0035904]; cardiac septum development [GO:0003279]; coronary vasculature development [GO:0060976]; extracellular matrix organization [GO:0030198]; kidney development [GO:0001822]; proteolysis [GO:0006508] GO:0001822; GO:0003279; GO:0004222; GO:0005576; GO:0006508; GO:0008237; GO:0030198; GO:0031012; GO:0035904; GO:0046872; GO:0060976 9471 XM_029351775.2 93 51 50 131 67 NA NA NA NA NA NA 9472 XM_029333460.2 227 152 85 93 339 P98192 3.56e-111 Dihydroxyacetone phosphate acyltransferase (DAP-AT) (DHAP-AT) (EC 2.3.1.42) (Acyl-CoA:dihydroxyacetonephosphateacyltransferase) (Glycerone-phosphate O-acyltransferase) Mus musculus (Mouse) cerebellum morphogenesis [GO:0021587]; ether lipid biosynthetic process [GO:0008611]; fatty acid metabolic process [GO:0006631]; glycerophospholipid metabolic process [GO:0006650]; membrane organization [GO:0061024]; myelination [GO:0042552]; paranodal junction assembly [GO:0030913]; phospholipid biosynthetic process [GO:0008654]; response to fatty acid [GO:0070542]; response to nutrient [GO:0007584]; response to starvation [GO:0042594]; response to xenobiotic stimulus [GO:0009410]; synapse assembly [GO:0007416] GO:0003824; GO:0005739; GO:0005777; GO:0005778; GO:0005782; GO:0006631; GO:0006650; GO:0007416; GO:0007584; GO:0008611; GO:0008654; GO:0009410; GO:0016287; GO:0021587; GO:0030913; GO:0031966; GO:0042552; GO:0042594; GO:0061024; GO:0070542 9473 XM_044327000.1 0 0 0 11 12 NA NA NA NA NA NA 9474 XM_029338246.2 86 29 62 72 100 NA NA NA NA NA NA 9475 XR_006392960.1 41 2 25 5 151 NA NA NA NA NA NA 9476 XM_029329370.2 468 342 195 376 276 NA NA NA NA NA NA 9477 XR_006397879.1 29 9 5 102 6 NA NA NA NA NA NA 9478 XM_044326721.1 1 0 0 81 0 NA NA NA NA NA NA 9479 XM_044316421.1 0 1 1 3 8 NA NA NA NA NA NA 9480 XR_006397680.1 221 241 372 471 367 NA NA NA NA NA NA 9481 XM_044321775.1 0 12 49 1 55 NA NA NA NA NA NA 9482 XM_044324829.1 947 1009 755 801 950 Q5ZJW4 4.98e-97 Vesicle-trafficking protein SEC22b (SEC22 vesicle-trafficking protein homolog B) Gallus gallus (Chicken) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; negative regulation of autophagosome assembly [GO:1902902]; positive regulation of protein catabolic process [GO:0045732]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; vesicle fusion with Golgi apparatus [GO:0048280] GO:0000139; GO:0005484; GO:0005789; GO:0005793; GO:0006888; GO:0006890; GO:0012507; GO:0015031; GO:0031201; GO:0033116; GO:0042470; GO:0045732; GO:0048280; GO:1902902 9483 XM_044318163.1 441 312 340 424 649 O42611 0 Protein HIRA (TUP1-like enhancer of split protein 1) Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) chromatin organization [GO:0006325]; DNA-templated transcription [GO:0006351]; regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006325; GO:0006351; GO:0006355 9484 XM_044318163.1 441 312 340 424 649 O42611 5.8e-66 Protein HIRA (TUP1-like enhancer of split protein 1) Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) chromatin organization [GO:0006325]; DNA-templated transcription [GO:0006351]; regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006325; GO:0006351; GO:0006355 9485 XM_044313268.1 924 199 354 448 244 Q8C033 9.47e-139 Rho guanine nucleotide exchange factor 10 Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; activation of GTPase activity [GO:0090630]; centrosome duplication [GO:0051298]; mitotic spindle assembly [GO:0090307]; myelination in peripheral nervous system [GO:0022011]; positive regulation of stress fiber assembly [GO:0051496] GO:0005085; GO:0005813; GO:0019894; GO:0022011; GO:0030036; GO:0051298; GO:0051496; GO:0090307; GO:0090630 9486 XM_044328652.1 66 375 39 54 48 Q5XI69 0 Probable ATP-dependent RNA helicase DHX40 (EC 3.6.4.13) (DEAH box protein 40) Rattus norvegicus (Rat) NA GO:0003723; GO:0003724; GO:0005524; GO:0016887 9487 XM_029346192.2 43 0 39 88 52 Q9I8C7 7.3e-91 Neuronal acetylcholine receptor subunit alpha-10 (Alpha 10 nAChR) (Nicotinic acetylcholine receptor subunit alpha-10) (NACHR alpha-10) Gallus gallus (Chicken) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; response to auditory stimulus [GO:0010996]; signal transduction [GO:0007165] GO:0004888; GO:0005231; GO:0005262; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0010996; GO:0022848; GO:0030594; GO:0034220; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051899; GO:1904315 9488 XM_044307881.1 22 8 107 17 81 NA NA NA NA NA NA 9489 XM_044316684.1 11 26 0 0 42 NA NA NA NA NA NA 9490 XM_044312317.1 25 0 0 34 0 NA NA NA NA NA NA 9491 XM_029344913.2 33 19 41 16 230 NA NA NA NA NA NA 9492 XM_029332258.2 102 69 71 143 53 Q9HCD5 4.95e-32 Nuclear receptor coactivator 5 (NCoA-5) (Coactivator independent of AF-2) (CIA) Homo sapiens (Human) glucose homeostasis [GO:0042593]; insulin receptor signaling pathway [GO:0008286]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of signal transduction [GO:0009966] GO:0000122; GO:0003682; GO:0003714; GO:0003723; GO:0005615; GO:0005654; GO:0008286; GO:0009966; GO:0015629; GO:0042593; GO:0046627 9493 XM_044319633.1 14 0 0 0 0 O94762 0 ATP-dependent DNA helicase Q5 (EC 3.6.4.12) (DNA helicase, RecQ-like type 5) (RecQ5) (RecQ protein-like 5) Homo sapiens (Human) cell division [GO:0051301]; cellular response to camptothecin [GO:0072757]; cellular response to ketone [GO:1901655]; cellular response to xenobiotic stimulus [GO:0071466]; chromosome separation [GO:0051304]; DNA duplex unwinding [GO:0032508]; DNA metabolic process [GO:0006259]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724]; mitotic cell cycle [GO:0000278]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; negative regulation of transcription elongation by RNA polymerase II [GO:0034244]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414] GO:0000278; GO:0000724; GO:0000993; GO:0003676; GO:0003678; GO:0005524; GO:0005634; GO:0005654; GO:0005694; GO:0005737; GO:0005829; GO:0006259; GO:0006260; GO:0006268; GO:0006281; GO:0006310; GO:0009378; GO:0016591; GO:0016887; GO:0032508; GO:0034244; GO:0042802; GO:0043138; GO:0051301; GO:0051304; GO:0071466; GO:0072757; GO:1901655; GO:1990414; GO:2000042 9494 XM_029336440.2 2595 2314 1478 2230 2208 P45985 9.14e-165 Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase 4) (MAPKK 4) (EC 2.7.12.2) (JNK-activating kinase 1) (MAPK/ERK kinase 4) (MEK 4) (SAPK/ERK kinase 1) (SEK1) (Stress-activated protein kinase kinase 1) (SAPK kinase 1) (SAPKK-1) (SAPKK1) (c-Jun N-terminal kinase kinase 1) (JNKK) Homo sapiens (Human) apoptotic process [GO:0006915]; cell growth involved in cardiac muscle cell development [GO:0061049]; cellular response to mechanical stimulus [GO:0071260]; cellular response to sorbitol [GO:0072709]; cellular senescence [GO:0090398]; Fc-epsilon receptor signaling pathway [GO:0038095]; JNK cascade [GO:0007254]; MAPK cascade [GO:0000165]; negative regulation of motor neuron apoptotic process [GO:2000672]; positive regulation of DNA replication [GO:0045740]; positive regulation of JNK cascade [GO:0046330]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]; response to wounding [GO:0009611]; signal transduction [GO:0007165] GO:0000165; GO:0001934; GO:0004672; GO:0004674; GO:0004708; GO:0004713; GO:0005524; GO:0005634; GO:0005829; GO:0006915; GO:0007165; GO:0007254; GO:0008545; GO:0009611; GO:0030424; GO:0032839; GO:0034393; GO:0038095; GO:0043204; GO:0043525; GO:0045740; GO:0046330; GO:0051770; GO:0060090; GO:0061049; GO:0071260; GO:0072709; GO:0090398; GO:0106310; GO:2000672 9495 XM_029338771.2 21 130 50 83 141 P42325 5.76e-110 Neurocalcin homolog (DrosNCa) Drosophila melanogaster (Fruit fly) negative regulation of neuronal signal transduction [GO:1902848]; positive regulation of circadian sleep/wake cycle, sleep [GO:0045938] GO:0005509; GO:0045938; GO:1902848 9496 XM_044308434.1 143 42 6 49 52 P69070 9.92e-57 Histone H2B Salmo trutta (Brown trout) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 9497 XM_029351836.2 1264 778 705 1105 1272 Q8CHW4 9.11e-155 Translation initiation factor eIF-2B subunit epsilon (eIF-2B GDP-GTP exchange factor subunit epsilon) Mus musculus (Mouse) aging [GO:0007568]; astrocyte development [GO:0014002]; astrocyte differentiation [GO:0048708]; hippocampus development [GO:0021766]; myelination [GO:0042552]; oligodendrocyte development [GO:0014003]; ovarian follicle development [GO:0001541]; positive regulation of apoptotic process [GO:0043065]; positive regulation of translation [GO:0045727]; positive regulation of translational initiation [GO:0045948]; response to endoplasmic reticulum stress [GO:0034976]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to lithium ion [GO:0010226]; response to peptide hormone [GO:0043434]; T cell receptor signaling pathway [GO:0050852]; translational initiation [GO:0006413] GO:0001541; GO:0003743; GO:0005085; GO:0005634; GO:0005737; GO:0005829; GO:0005851; GO:0006413; GO:0007568; GO:0009408; GO:0009749; GO:0010226; GO:0014002; GO:0014003; GO:0021766; GO:0031369; GO:0034976; GO:0042552; GO:0043065; GO:0043434; GO:0045727; GO:0045948; GO:0048708; GO:0050852 9498 XM_029355726.2 940 772 508 1061 944 Q9Z160 7.03e-165 Conserved oligomeric Golgi complex subunit 1 (COG complex subunit 1) (Component of oligomeric Golgi complex 1) (Low density lipoprotein receptor defect B-complementing protein) Mus musculus (Mouse) glycosylation [GO:0070085]; Golgi organization [GO:0007030]; protein transport [GO:0015031]; retrograde transport, vesicle recycling within Golgi [GO:0000301] GO:0000139; GO:0000301; GO:0005794; GO:0007030; GO:0015031; GO:0017119; GO:0070085 9499 XM_044308806.1 100 148 156 18 77 NA NA NA NA NA NA 9500 XM_029344070.2 373 163 38 195 102 NA NA NA NA NA NA 9501 XM_044310487.1 1 0 0 0 217 NA NA NA NA NA NA 9502 XM_029339287.2 116 0 0 0 248 Q9H6D7 1.61e-27 HAUS augmin-like complex subunit 4 Homo sapiens (Human) cell division [GO:0051301]; centrosome cycle [GO:0007098]; spindle assembly [GO:0051225] GO:0005813; GO:0005829; GO:0007098; GO:0051011; GO:0051225; GO:0051301; GO:0070652; GO:1990498 9503 XM_044307488.1 0 0 1 7 6 NA NA NA NA NA NA 9504 XM_044319242.1 68 93 0 2 48 NA NA NA NA NA NA 9505 XM_029351854.2 777 768 471 716 1016 NA NA NA NA NA NA 9506 XM_029338999.2 0 62 0 0 0 Q9D2K4 0 IQ domain-containing protein H Mus musculus (Mouse) NA NA 9507 XM_029329728.2 915 1024 580 574 1316 Q99685 1.66e-76 Monoglyceride lipase (MGL) (EC 3.1.1.23) (HU-K5) (Lysophospholipase homolog) (Lysophospholipase-like) (Monoacylglycerol lipase) (MAGL) Homo sapiens (Human) acylglycerol catabolic process [GO:0046464]; arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; inflammatory response [GO:0006954]; lipid metabolic process [GO:0006629]; monoacylglycerol catabolic process [GO:0052651]; regulation of endocannabinoid signaling pathway [GO:2000124]; regulation of inflammatory response [GO:0050727]; regulation of sensory perception of pain [GO:0051930]; regulation of signal transduction [GO:0009966]; triglyceride catabolic process [GO:0019433] GO:0004622; GO:0005654; GO:0005789; GO:0005829; GO:0005886; GO:0006629; GO:0006633; GO:0006954; GO:0009966; GO:0016020; GO:0016298; GO:0019369; GO:0019433; GO:0019898; GO:0042803; GO:0046464; GO:0047372; GO:0050727; GO:0051930; GO:0052651; GO:2000124 9508 XM_044317986.1 12 0 0 0 0 NA NA NA NA NA NA 9509 XM_044321173.1 0 6 0 4 6 NA NA NA NA NA NA 9510 XM_044308669.1 4 81 5 6 0 Q96DM1 6.65e-31 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 9511 XR_006397097.1 0 0 13 0 0 NA NA NA NA NA NA 9512 XM_029338278.2 1589 1526 941 1785 1760 Q62763 0 Casein kinase I isoform gamma-3 (CKI-gamma 3) (EC 2.7.11.1) Rattus norvegicus (Rat) endocytosis [GO:0006897]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055] GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005886; GO:0006468; GO:0006897; GO:0007165; GO:0016055; GO:0018105; GO:0046777; GO:0090263; GO:0106310 9513 XR_006393776.1 2 1 12 2 23 NA NA NA NA NA NA 9514 XM_029342838.2 0 0 0 0 89 P81439 2.33e-33 Equistatin (EI) (Cysteine proteinase inhibitor) Actinia equina (Beadlet anemone) negative regulation of peptidase activity [GO:0010466] GO:0004869; GO:0005576; GO:0010466 9515 XM_029342838.2 0 0 0 0 89 P81439 1.02e-32 Equistatin (EI) (Cysteine proteinase inhibitor) Actinia equina (Beadlet anemone) negative regulation of peptidase activity [GO:0010466] GO:0004869; GO:0005576; GO:0010466 9516 XM_029342838.2 0 0 0 0 89 P81439 2.04e-32 Equistatin (EI) (Cysteine proteinase inhibitor) Actinia equina (Beadlet anemone) negative regulation of peptidase activity [GO:0010466] GO:0004869; GO:0005576; GO:0010466 9517 XM_029342838.2 0 0 0 0 89 P81439 4.04e-32 Equistatin (EI) (Cysteine proteinase inhibitor) Actinia equina (Beadlet anemone) negative regulation of peptidase activity [GO:0010466] GO:0004869; GO:0005576; GO:0010466 9518 XM_029342838.2 0 0 0 0 89 P81439 3.39e-30 Equistatin (EI) (Cysteine proteinase inhibitor) Actinia equina (Beadlet anemone) negative regulation of peptidase activity [GO:0010466] GO:0004869; GO:0005576; GO:0010466 9519 XM_029342838.2 0 0 0 0 89 P81439 1.07e-28 Equistatin (EI) (Cysteine proteinase inhibitor) Actinia equina (Beadlet anemone) negative regulation of peptidase activity [GO:0010466] GO:0004869; GO:0005576; GO:0010466 9520 XM_029342838.2 0 0 0 0 89 P81439 8.32e-28 Equistatin (EI) (Cysteine proteinase inhibitor) Actinia equina (Beadlet anemone) negative regulation of peptidase activity [GO:0010466] GO:0004869; GO:0005576; GO:0010466 9521 XM_029342838.2 0 0 0 0 89 P81439 5.67e-27 Equistatin (EI) (Cysteine proteinase inhibitor) Actinia equina (Beadlet anemone) negative regulation of peptidase activity [GO:0010466] GO:0004869; GO:0005576; GO:0010466 9522 XM_029342838.2 0 0 0 0 89 P81439 1.99e-26 Equistatin (EI) (Cysteine proteinase inhibitor) Actinia equina (Beadlet anemone) negative regulation of peptidase activity [GO:0010466] GO:0004869; GO:0005576; GO:0010466 9523 XM_029342838.2 0 0 0 0 89 P81439 2.82e-22 Equistatin (EI) (Cysteine proteinase inhibitor) Actinia equina (Beadlet anemone) negative regulation of peptidase activity [GO:0010466] GO:0004869; GO:0005576; GO:0010466 9524 XM_029342838.2 0 0 0 0 89 P81439 2.44e-21 Equistatin (EI) (Cysteine proteinase inhibitor) Actinia equina (Beadlet anemone) negative regulation of peptidase activity [GO:0010466] GO:0004869; GO:0005576; GO:0010466 9525 XM_029342838.2 0 0 0 0 89 P81439 7.4e-21 Equistatin (EI) (Cysteine proteinase inhibitor) Actinia equina (Beadlet anemone) negative regulation of peptidase activity [GO:0010466] GO:0004869; GO:0005576; GO:0010466 9526 XM_044313588.1 22 4 0 0 0 NA NA NA NA NA NA 9527 XR_006396401.1 57 71 58 93 30 NA NA NA NA NA NA 9528 XM_029356305.2 600 228 152 519 531 L5KLU7 1.1e-46 NA NA NA NA 9529 XR_006396083.1 5 19 0 6 11 NA NA NA NA NA NA 9530 XM_044319725.1 0 0 296 0 243 Q9VS29 3.7e-28 Cell adhesion molecule Dscam2 (Down syndrome cell adhesion molecule-like protein Dscam2) Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; dendrite self-avoidance [GO:0070593]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron projection morphogenesis [GO:0048812] GO:0005886; GO:0007156; GO:0007411; GO:0030424; GO:0042802; GO:0048812; GO:0070593; GO:0098632 9531 XM_044319725.1 0 0 296 0 243 Q9VS29 7.34e-21 Cell adhesion molecule Dscam2 (Down syndrome cell adhesion molecule-like protein Dscam2) Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; dendrite self-avoidance [GO:0070593]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron projection morphogenesis [GO:0048812] GO:0005886; GO:0007156; GO:0007411; GO:0030424; GO:0042802; GO:0048812; GO:0070593; GO:0098632 9532 XR_003826686.2 37 66 56 42 82 NA NA NA NA NA NA 9533 XM_044313037.1 6 0 0 0 4 Q96AY4 7.17e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9534 XM_044313880.1 13 6 7 7 9 NA NA NA NA NA NA 9535 XM_029336579.2 0 54 0 0 0 Q66KD6 2.32e-52 Probable phosphatase phospho2 (EC 3.1.3.-) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0016791; GO:0046872 9536 XR_006395506.1 101 0 1 112 23 NA NA NA NA NA NA 9537 XM_029352090.2 172 58 7 63 88 NA NA NA NA NA NA 9538 XM_029337880.2 17 0 7 0 0 NA NA NA NA NA NA 9539 XR_003823979.2 5 0 0 11 85 NA NA NA NA NA NA 9540 XM_044312860.1 197 160 92 19 9 Q6AXS0 1.32e-98 Mitochondrial sodium/calcium exchanger protein (Na(+)/K(+)/Ca(2+)-exchange protein 6) (Sodium/calcium exchanger protein, mitochondrial) (Sodium/potassium/calcium exchanger 6) (Solute carrier family 24 member 6) (Solute carrier family 8 member B1) Rattus norvegicus (Rat) calcium export from the mitochondrion [GO:0099093]; calcium ion transmembrane transport [GO:0070588]; cation transport [GO:0006812]; cellular calcium ion homeostasis [GO:0006874]; glucose homeostasis [GO:0042593]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrial calcium ion transmembrane transport [GO:0006851]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of insulin secretion [GO:0050796]; regulation of lymphocyte chemotaxis [GO:1901623]; regulation of store-operated calcium entry [GO:2001256]; response to stimulus [GO:0050896]; sodium ion transmembrane transport [GO:0035725] GO:0005432; GO:0005739; GO:0005743; GO:0005886; GO:0006812; GO:0006851; GO:0006874; GO:0008324; GO:0016020; GO:0030061; GO:0031966; GO:0035725; GO:0042383; GO:0042593; GO:0042802; GO:0042803; GO:0050796; GO:0050896; GO:0051480; GO:0051560; GO:0070588; GO:0086038; GO:0099093; GO:1901623; GO:2001256 9541 XM_044317801.1 40 0 50 60 271 A0A0H2VDN9 1.19e-24 Secretory immunoglobulin A-binding protein EsiB Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) negative regulation of immune response [GO:0050777]; negative regulation of neutrophil activation [GO:1902564] GO:0009986; GO:0019862; GO:0046872; GO:0050777; GO:1902564 9542 XM_044317801.1 40 0 50 60 271 A0A0H2VDN9 1.69e-24 Secretory immunoglobulin A-binding protein EsiB Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) negative regulation of immune response [GO:0050777]; negative regulation of neutrophil activation [GO:1902564] GO:0009986; GO:0019862; GO:0046872; GO:0050777; GO:1902564 9543 XM_044317801.1 40 0 50 60 271 A0A0H2VDN9 5.93e-21 Secretory immunoglobulin A-binding protein EsiB Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) negative regulation of immune response [GO:0050777]; negative regulation of neutrophil activation [GO:1902564] GO:0009986; GO:0019862; GO:0046872; GO:0050777; GO:1902564 9544 XM_029344216.2 0 0 0 97 0 O70422 0 General transcription factor IIH subunit 4 (Basic transcription factor 2 52 kDa subunit) (BTF2 p52) (General transcription factor IIH polypeptide 4) (TFIIH basal transcription factor complex p52 subunit) Mus musculus (Mouse) nucleotide-excision repair [GO:0006289]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; transcription by RNA polymerase II [GO:0006366] GO:0000438; GO:0000439; GO:0001671; GO:0003690; GO:0005634; GO:0005669; GO:0005675; GO:0006289; GO:0006366; GO:0016251; GO:0016607; GO:0070816 9545 XM_044325269.1 0 8 0 3 18 P35555 1.52e-45 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 9546 XM_044325269.1 0 8 0 3 18 P35555 3.57e-44 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 9547 XM_044325269.1 0 8 0 3 18 P35555 2.2e-40 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 9548 XM_044325269.1 0 8 0 3 18 P35555 1.27e-34 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 9549 XM_044325269.1 0 8 0 3 18 P35555 1.86e-34 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 9550 XM_044325269.1 0 8 0 3 18 P35555 1.18e-31 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 9551 XM_044325269.1 0 8 0 3 18 P35555 1.79e-31 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 9552 XM_044325269.1 0 8 0 3 18 P35555 8.65e-27 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 9553 XM_044325269.1 0 8 0 3 18 P35555 6.62e-26 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 9554 XM_044325269.1 0 8 0 3 18 P35555 1.17e-25 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 9555 XM_044325269.1 0 8 0 3 18 P35555 1.36e-24 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 9556 XM_044325269.1 0 8 0 3 18 P35555 3.65e-24 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 9557 XM_044325269.1 0 8 0 3 18 P35555 7.75e-24 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 9558 XM_044325269.1 0 8 0 3 18 P35555 1.34e-23 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 9559 XM_044325269.1 0 8 0 3 18 P35555 3.15e-22 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 9560 XM_044325269.1 0 8 0 3 18 P35555 7.91e-22 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 9561 XR_006396438.1 96 25 34 43 26 NA NA NA NA NA NA 9562 XM_029345167.2 482 241 218 581 589 Q8IVH4 5.76e-139 Methylmalonic aciduria type A protein, mitochondrial (EC 3.6.-.-) Homo sapiens (Human) cobalamin metabolic process [GO:0009235] GO:0003924; GO:0005525; GO:0005737; GO:0005739; GO:0005759; GO:0005829; GO:0009235; GO:0042802; GO:0042803 9563 XM_029327037.2 162 108 112 189 137 P81139 3.24e-56 Pancreatic lipase-related protein 2 (PL-RP2) (Cytotoxic T lymphocyte lipase) (GPL) (Galactolipase) (EC 3.1.1.26) (Triacylglycerol lipase) (EC 3.1.1.3) Cavia porcellus (Guinea pig) galactolipid catabolic process [GO:0019376]; lipid metabolic process [GO:0006629]; phospholipid catabolic process [GO:0009395]; phospholipid metabolic process [GO:0006644]; triglyceride catabolic process [GO:0019433] GO:0004620; GO:0004806; GO:0005509; GO:0005615; GO:0006629; GO:0006644; GO:0009395; GO:0016020; GO:0019376; GO:0019433; GO:0031410; GO:0043005; GO:0047372; GO:0047714; GO:0102549 9564 XM_044316576.1 3 7 9 5 46 P79218 9.45e-41 Substance-K receptor (SKR) (NK-2 receptor) (NK-2R) (Neurokinin A receptor) (Tachykinin receptor 2) Oryctolagus cuniculus (Rabbit) positive regulation of flagellated sperm motility [GO:1902093]; regulation of uterine smooth muscle contraction [GO:0070472] GO:0004995; GO:0005886; GO:0061827; GO:0070472; GO:0097225; GO:1902093 9565 XM_044320261.1 378 166 216 300 345 Q7YQM4 5.04e-131 Transcriptional regulator ATRX (EC 3.6.4.12) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) Pan troglodytes (Chimpanzee) cellular response to hydroxyurea [GO:0072711]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; chromosome organization involved in meiotic cell cycle [GO:0070192]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA repair [GO:0006281]; forebrain development [GO:0030900]; meiotic spindle organization [GO:0000212]; multicellular organism growth [GO:0035264]; negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric [GO:1904908]; nucleosome assembly [GO:0006334]; positive regulation of nuclear cell cycle DNA replication [GO:0010571]; positive regulation of telomere maintenance [GO:0032206]; positive regulation of telomeric RNA transcription from RNA pol II promoter [GO:1901582]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic forelimb morphogenesis [GO:0035128]; protein localization to chromosome, telomeric region [GO:0070198]; replication fork processing [GO:0031297]; seminiferous tubule development [GO:0072520]; Sertoli cell development [GO:0060009]; spermatogenesis [GO:0007283]; subtelomeric heterochromatin formation [GO:0031509]; transcription by RNA polymerase II [GO:0006366] GO:0000212; GO:0000228; GO:0000779; GO:0000781; GO:0003682; GO:0004386; GO:0005524; GO:0005634; GO:0005721; GO:0006281; GO:0006325; GO:0006334; GO:0006338; GO:0006366; GO:0007283; GO:0010571; GO:0015616; GO:0016605; GO:0016887; GO:0030330; GO:0030900; GO:0031297; GO:0031490; GO:0031509; GO:0032206; GO:0035064; GO:0035128; GO:0035264; GO:0042393; GO:0045944; GO:0046872; GO:0060009; GO:0070087; GO:0070192; GO:0070198; GO:0072520; GO:0072711; GO:0099115; GO:0140658; GO:1901582; GO:1904908 9566 XM_044320261.1 378 166 216 300 345 Q7YQM4 2.05e-76 Transcriptional regulator ATRX (EC 3.6.4.12) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) Pan troglodytes (Chimpanzee) cellular response to hydroxyurea [GO:0072711]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; chromosome organization involved in meiotic cell cycle [GO:0070192]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA repair [GO:0006281]; forebrain development [GO:0030900]; meiotic spindle organization [GO:0000212]; multicellular organism growth [GO:0035264]; negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric [GO:1904908]; nucleosome assembly [GO:0006334]; positive regulation of nuclear cell cycle DNA replication [GO:0010571]; positive regulation of telomere maintenance [GO:0032206]; positive regulation of telomeric RNA transcription from RNA pol II promoter [GO:1901582]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic forelimb morphogenesis [GO:0035128]; protein localization to chromosome, telomeric region [GO:0070198]; replication fork processing [GO:0031297]; seminiferous tubule development [GO:0072520]; Sertoli cell development [GO:0060009]; spermatogenesis [GO:0007283]; subtelomeric heterochromatin formation [GO:0031509]; transcription by RNA polymerase II [GO:0006366] GO:0000212; GO:0000228; GO:0000779; GO:0000781; GO:0003682; GO:0004386; GO:0005524; GO:0005634; GO:0005721; GO:0006281; GO:0006325; GO:0006334; GO:0006338; GO:0006366; GO:0007283; GO:0010571; GO:0015616; GO:0016605; GO:0016887; GO:0030330; GO:0030900; GO:0031297; GO:0031490; GO:0031509; GO:0032206; GO:0035064; GO:0035128; GO:0035264; GO:0042393; GO:0045944; GO:0046872; GO:0060009; GO:0070087; GO:0070192; GO:0070198; GO:0072520; GO:0072711; GO:0099115; GO:0140658; GO:1901582; GO:1904908 9567 XM_044320261.1 378 166 216 300 345 Q7YQM4 2.65e-31 Transcriptional regulator ATRX (EC 3.6.4.12) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) Pan troglodytes (Chimpanzee) cellular response to hydroxyurea [GO:0072711]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; chromosome organization involved in meiotic cell cycle [GO:0070192]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA repair [GO:0006281]; forebrain development [GO:0030900]; meiotic spindle organization [GO:0000212]; multicellular organism growth [GO:0035264]; negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric [GO:1904908]; nucleosome assembly [GO:0006334]; positive regulation of nuclear cell cycle DNA replication [GO:0010571]; positive regulation of telomere maintenance [GO:0032206]; positive regulation of telomeric RNA transcription from RNA pol II promoter [GO:1901582]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic forelimb morphogenesis [GO:0035128]; protein localization to chromosome, telomeric region [GO:0070198]; replication fork processing [GO:0031297]; seminiferous tubule development [GO:0072520]; Sertoli cell development [GO:0060009]; spermatogenesis [GO:0007283]; subtelomeric heterochromatin formation [GO:0031509]; transcription by RNA polymerase II [GO:0006366] GO:0000212; GO:0000228; GO:0000779; GO:0000781; GO:0003682; GO:0004386; GO:0005524; GO:0005634; GO:0005721; GO:0006281; GO:0006325; GO:0006334; GO:0006338; GO:0006366; GO:0007283; GO:0010571; GO:0015616; GO:0016605; GO:0016887; GO:0030330; GO:0030900; GO:0031297; GO:0031490; GO:0031509; GO:0032206; GO:0035064; GO:0035128; GO:0035264; GO:0042393; GO:0045944; GO:0046872; GO:0060009; GO:0070087; GO:0070192; GO:0070198; GO:0072520; GO:0072711; GO:0099115; GO:0140658; GO:1901582; GO:1904908 9568 XM_044306841.1 17 33 10 7 7 NA NA NA NA NA NA 9569 XR_006395399.1 13 0 0 0 8 NA NA NA NA NA NA 9570 XR_003823943.2 1 6 1 4 2 NA NA NA NA NA NA 9571 XM_029336972.2 12 4 134 48 0 P51869 3.09e-106 Cytochrome P450 4F4 (CYPIVF4) (Leukotriene-B4 20-monooxygenase) (EC 1.14.14.94) Rattus norvegicus (Rat) arachidonic acid metabolic process [GO:0019369]; leukotriene B4 catabolic process [GO:0036101]; menaquinone catabolic process [GO:0042361]; omega-hydroxylase P450 pathway [GO:0097267]; phylloquinone catabolic process [GO:0042376]; prostaglandin catabolic process [GO:1905344] GO:0005506; GO:0005789; GO:0008391; GO:0019369; GO:0020037; GO:0036101; GO:0042361; GO:0042376; GO:0043231; GO:0050051; GO:0097267; GO:1905344 9572 XM_044328255.1 1968 1861 1861 1946 2380 Q6AYH6 5.06e-27 ER membrane protein complex subunit 10 Rattus norvegicus (Rat) angiogenesis [GO:0001525]; positive regulation of angiogenesis [GO:0045766]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of p38MAPK cascade [GO:1900745]; protein insertion into ER membrane by stop-transfer membrane-anchor sequence [GO:0045050]; tail-anchored membrane protein insertion into ER membrane [GO:0071816] GO:0001525; GO:0001938; GO:0005576; GO:0005789; GO:0010595; GO:0016020; GO:0045050; GO:0045766; GO:0071816; GO:0072546; GO:1900745 9573 XM_029343094.2 857 641 673 954 911 Q9XT06 0 T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha) Monodelphis domestica (Gray short-tailed opossum) protein folding [GO:0006457] GO:0005524; GO:0005815; GO:0005832; GO:0006457; GO:0016887; GO:0051082; GO:0140662 9574 XR_003824593.2 0 0 12 14 24 NA NA NA NA NA NA 9575 XM_044327016.1 0 0 0 0 90 NA NA NA NA NA NA 9576 XM_029331503.2 1249 919 886 1533 1130 Q13627 0 Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.11.23) (EC 2.7.12.1) (Dual specificity YAK1-related kinase) (HP86) (Protein kinase minibrain homolog) (MNBH) (hMNB) Homo sapiens (Human) amyloid-beta formation [GO:0034205]; circadian rhythm [GO:0007623]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of DNA methylation-dependent heterochromatin formation [GO:0090310]; negative regulation of microtubule polymerization [GO:0031115]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; nervous system development [GO:0007399]; peptidyl-serine autophosphorylation [GO:0036289]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of protein deacetylation [GO:0090312]; positive regulation of RNA splicing [GO:0033120]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468] GO:0003713; GO:0003779; GO:0004672; GO:0004674; GO:0004712; GO:0004713; GO:0004715; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005856; GO:0006468; GO:0007399; GO:0007623; GO:0008092; GO:0008353; GO:0015631; GO:0016607; GO:0018105; GO:0018107; GO:0018108; GO:0030424; GO:0030425; GO:0031115; GO:0033120; GO:0034205; GO:0036289; GO:0038083; GO:0042802; GO:0043518; GO:0043621; GO:0045893; GO:0046777; GO:0048025; GO:0048156; GO:0050321; GO:0090310; GO:0090312; GO:0106310; GO:0140857; GO:1990904 9577 XM_044315214.1 715 415 355 646 289 Q6NY52 1.85e-151 THO complex subunit 5 homolog Danio rerio (Zebrafish) (Brachydanio rerio) cell differentiation [GO:0030154]; mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; RNA splicing [GO:0008380] GO:0000445; GO:0003729; GO:0005737; GO:0006397; GO:0006406; GO:0008380; GO:0016607; GO:0030154; GO:0032786 9578 XM_029329392.2 203 627 433 672 434 NA NA NA NA NA NA 9579 XM_029349527.2 116 128 44 71 59 NA NA NA NA NA NA 9580 XM_044310933.1 9742 1960 8720 7596 7196 NA NA NA NA NA NA 9581 XM_029342047.2 363 202 243 185 146 Q9ULM6 0 CCR4-NOT transcription complex subunit 6 (EC 3.1.13.4) (CCR4 carbon catabolite repression 4-like) (Carbon catabolite repressor protein 4 homolog) (Cytoplasmic deadenylase) Homo sapiens (Human) exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; miRNA-mediated gene silencing [GO:0035195]; nuclear-transcribed mRNA catabolic process, no-go decay [GO:0070966]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytoplasmic mRNA processing body assembly [GO:0010606] GO:0000175; GO:0000289; GO:0003723; GO:0004532; GO:0004535; GO:0005634; GO:0005737; GO:0005829; GO:0008284; GO:0010606; GO:0016020; GO:0030014; GO:0030374; GO:0035195; GO:0043928; GO:0046872; GO:0070966 9582 XM_044311216.1 14 18 45 0 0 P46023 1.22e-107 G-protein coupled receptor GRL101 Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004930; GO:0005886 9583 XM_044312944.1 13 27 2 0 0 NA NA NA NA NA NA 9584 XM_029326203.1 7 114 0 0 262 NA NA NA NA NA NA 9585 XM_044328669.1 0 0 10 0 0 Q6V0K7 8.76e-50 Oncoprotein-induced transcript 3 protein (Liver-specific zona pellucida domain-containing protein) Rattus norvegicus (Rat) urate homeostasis [GO:1903118] GO:0005201; GO:0005509; GO:0005615; GO:0005635; GO:0009986; GO:1903118 9586 XM_029340185.2 849 635 745 565 379 A8DZE6 3.44e-59 Wilms tumor protein 1-interacting protein homolog (WT1-interacting protein homolog) Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; cloaca development [GO:0035844]; cytoskeleton organization [GO:0007010]; determination of heart left/right asymmetry [GO:0061371]; determination of left/right asymmetry in lateral mesoderm [GO:0003140]; establishment of mitotic spindle orientation [GO:0000132]; heart looping [GO:0001947]; negative regulation of hippo signaling [GO:0035331]; neural crest cell development [GO:0014032]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; regulation of cell morphogenesis [GO:0022604]; regulation of DNA-templated transcription [GO:0006355]; response to hypoxia [GO:0001666]; visceral serous pericardium development [GO:0061032] GO:0000132; GO:0000932; GO:0001666; GO:0001947; GO:0003140; GO:0003714; GO:0005634; GO:0005667; GO:0005912; GO:0006355; GO:0007010; GO:0014032; GO:0022604; GO:0035331; GO:0035844; GO:0036064; GO:0046872; GO:0060271; GO:0061032; GO:0061371; GO:2000637 9587 XM_029324754.2 6044 6144 3944 7693 6491 Q3T0T7 2.53e-95 GTP-binding protein SAR1b Bos taurus (Bovine) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; lipid homeostasis [GO:0055088]; lipoprotein transport [GO:0042953]; membrane organization [GO:0061024]; positive regulation of protein exit from endoplasmic reticulum [GO:0070863]; regulation of COPII vesicle coating [GO:0003400]; regulation of lipid transport [GO:0032368]; vesicle organization [GO:0016050] GO:0003400; GO:0003924; GO:0005525; GO:0005789; GO:0006886; GO:0006888; GO:0016050; GO:0030127; GO:0032368; GO:0032580; GO:0042953; GO:0046872; GO:0055088; GO:0061024; GO:0070863; GO:0070971 9588 XM_044326724.1 3 2 11 5 9 NA NA NA NA NA NA 9589 XM_029340039.2 500 36 82 494 513 F1QB81 1.29e-21 NA NA NA NA 9590 XM_044311937.1 0 0 0 7 1 NA NA NA NA NA NA 9591 XM_029329870.2 0 1115 0 3 0 P20072 4.24e-70 Annexin A7 (Annexin VII) (Annexin-7) (Synexin) Bos taurus (Bovine) NA GO:0005509; GO:0005544; GO:0005634; GO:0005737; GO:0042584 9592 XR_003828413.2 15 18 0 0 39 Q86UD5 9.6e-110 Sodium/hydrogen exchanger 9B2 (Na(+)/H(+) exchanger NHA2) (Na(+)/H(+) exchanger-like domain-containing protein 2) (NHE domain-containing protein 2) (Sodium/hydrogen exchanger-like domain-containing protein 2) (Solute carrier family 9 subfamily B member 2) Homo sapiens (Human) clathrin-dependent endocytosis [GO:0072583]; flagellated sperm motility [GO:0030317]; ion transmembrane transport [GO:0034220]; positive regulation of osteoclast development [GO:2001206]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; sodium ion transport [GO:0006814] GO:0005743; GO:0005886; GO:0006814; GO:0010008; GO:0010348; GO:0015385; GO:0016323; GO:0016324; GO:0030317; GO:0030672; GO:0031966; GO:0034220; GO:0042802; GO:0061178; GO:0072583; GO:0097228; GO:2001206 9593 XM_029328633.2 101 82 29 129 311 NA NA NA NA NA NA 9594 XM_029341057.2 1180 1476 1125 904 897 Q5BJW3 2.02e-54 Protein TEX261 Rattus norvegicus (Rat) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of apoptotic process [GO:0043065] GO:0000139; GO:0005789; GO:0006888; GO:0030134; GO:0043065; GO:0097020 9595 XM_029357766.2 9 8 32 82 61 P21728 8.37e-31 D(1A) dopamine receptor (Dopamine D1 receptor) Homo sapiens (Human) activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adult walking behavior [GO:0007628]; astrocyte development [GO:0014002]; behavioral fear response [GO:0001662]; behavioral response to cocaine [GO:0048148]; cellular response to catecholamine stimulus [GO:0071870]; cellular response to dopamine [GO:1903351]; cerebral cortex GABAergic interneuron migration [GO:0021853]; conditioned taste aversion [GO:0001661]; dentate gyrus development [GO:0021542]; dopamine metabolic process [GO:0042417]; dopamine receptor signaling pathway [GO:0007212]; dopamine transport [GO:0015872]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; glucose import [GO:0046323]; grooming behavior [GO:0007625]; habituation [GO:0046959]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; maternal behavior [GO:0042711]; mating behavior [GO:0007617]; memory [GO:0007613]; modification of postsynaptic structure [GO:0099010]; neuronal action potential [GO:0019228]; operant conditioning [GO:0035106]; peristalsis [GO:0030432]; phospholipase C-activating dopamine receptor signaling pathway [GO:0060158]; positive regulation of cell migration [GO:0030335]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transport [GO:0043268]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; prepulse inhibition [GO:0060134]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; protein import into nucleus [GO:0006606]; protein phosphorylation [GO:0006468]; regulation of dopamine metabolic process [GO:0042053]; regulation of dopamine uptake involved in synaptic transmission [GO:0051584]; regulation of protein phosphorylation [GO:0001932]; response to amphetamine [GO:0001975]; response to xenobiotic stimulus [GO:0009410]; sensitization [GO:0046960]; striatum development [GO:0021756]; synapse assembly [GO:0007416]; synaptic transmission, glutamatergic [GO:0035249]; temperature homeostasis [GO:0001659]; transmission of nerve impulse [GO:0019226]; vasodilation [GO:0042311]; visual learning [GO:0008542] GO:0001588; GO:0001659; GO:0001661; GO:0001662; GO:0001932; GO:0001975; GO:0004930; GO:0004952; GO:0005634; GO:0005789; GO:0005886; GO:0005929; GO:0006468; GO:0006606; GO:0007187; GO:0007189; GO:0007190; GO:0007191; GO:0007212; GO:0007416; GO:0007613; GO:0007617; GO:0007625; GO:0007628; GO:0008542; GO:0009410; GO:0010628; GO:0014002; GO:0015872; GO:0019226; GO:0019228; GO:0021542; GO:0021756; GO:0021853; GO:0030335; GO:0030432; GO:0035106; GO:0035240; GO:0035249; GO:0042053; GO:0042311; GO:0042417; GO:0042711; GO:0042734; GO:0043197; GO:0043268; GO:0045211; GO:0046323; GO:0046959; GO:0046960; GO:0048148; GO:0051281; GO:0051482; GO:0051584; GO:0051968; GO:0060134; GO:0060158; GO:0060170; GO:0060291; GO:0060292; GO:0071870; GO:0071880; GO:0097730; GO:0098978; GO:0098982; GO:0099010; GO:0099171; GO:1903351; GO:2001224 9596 XR_006393982.1 6 0 0 18 21 NA NA NA NA NA NA 9597 XM_044309247.1 89 213 72 75 194 Q91VS8 2e-154 FERM, ARHGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR) (FERM, RhoGEF and pleckstrin domain-containing protein 2) Mus musculus (Mouse) actin cytoskeleton reorganization [GO:0031532]; cell adhesion [GO:0007155]; hair cycle process [GO:0022405]; neuron remodeling [GO:0016322]; osteoclast differentiation [GO:0030316]; podosome assembly [GO:0071800]; Rac protein signal transduction [GO:0016601]; regulation of integrin activation [GO:0033623]; semaphorin-plexin signaling pathway [GO:0071526] GO:0005085; GO:0005737; GO:0005829; GO:0005856; GO:0007155; GO:0008092; GO:0016322; GO:0016601; GO:0022405; GO:0030316; GO:0031532; GO:0033623; GO:0071526; GO:0071800 9598 XM_044309247.1 89 213 72 75 194 Q91VS8 4.51e-68 FERM, ARHGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR) (FERM, RhoGEF and pleckstrin domain-containing protein 2) Mus musculus (Mouse) actin cytoskeleton reorganization [GO:0031532]; cell adhesion [GO:0007155]; hair cycle process [GO:0022405]; neuron remodeling [GO:0016322]; osteoclast differentiation [GO:0030316]; podosome assembly [GO:0071800]; Rac protein signal transduction [GO:0016601]; regulation of integrin activation [GO:0033623]; semaphorin-plexin signaling pathway [GO:0071526] GO:0005085; GO:0005737; GO:0005829; GO:0005856; GO:0007155; GO:0008092; GO:0016322; GO:0016601; GO:0022405; GO:0030316; GO:0031532; GO:0033623; GO:0071526; GO:0071800 9599 XM_029356174.2 28 15 0 36 0 NA NA NA NA NA NA 9600 XM_029346772.2 199 83 82 118 283 NA NA NA NA NA NA 9601 XM_044315469.1 70 5 62 7 336 NA NA NA NA NA NA 9602 XM_044317890.1 95 46 54 57 26 NA NA NA NA NA NA 9603 XR_003827072.2 417 246 191 457 362 NA NA NA NA NA NA 9604 XM_029335688.2 1486 1040 859 1491 1004 Q0KHQ5 7.33e-162 Serine/threonine-protein kinase Tao (EC 2.7.11.1) Drosophila melanogaster (Fruit fly) apoptotic process [GO:0006915]; central complex development [GO:0048036]; follicle cell of egg chamber development [GO:0030707]; intestinal stem cell homeostasis [GO:0036335]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; mushroom body development [GO:0016319]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of organ growth [GO:0046621]; negative regulation of synaptic assembly at neuromuscular junction [GO:0045886]; neuron projection morphogenesis [GO:0048812]; positive regulation of endocytosis [GO:0045807]; positive regulation of hippo signaling [GO:0035332]; protein phosphorylation [GO:0006468]; R8 cell fate commitment [GO:0007460]; regulation of MAPK cascade [GO:0043408]; response to cocaine [GO:0042220]; response to ethanol [GO:0045471]; response to nicotine [GO:0035094]; tissue homeostasis [GO:0001894] GO:0000165; GO:0001894; GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0005819; GO:0005874; GO:0005886; GO:0005938; GO:0006468; GO:0006915; GO:0007460; GO:0016020; GO:0016319; GO:0030424; GO:0030514; GO:0030707; GO:0035094; GO:0035332; GO:0035556; GO:0036335; GO:0042220; GO:0043204; GO:0043408; GO:0045178; GO:0045471; GO:0045807; GO:0045886; GO:0046621; GO:0048036; GO:0048812; GO:0106310 9605 XM_029335688.2 1486 1040 859 1491 1004 Q0KHQ5 6.17e-86 Serine/threonine-protein kinase Tao (EC 2.7.11.1) Drosophila melanogaster (Fruit fly) apoptotic process [GO:0006915]; central complex development [GO:0048036]; follicle cell of egg chamber development [GO:0030707]; intestinal stem cell homeostasis [GO:0036335]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; mushroom body development [GO:0016319]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of organ growth [GO:0046621]; negative regulation of synaptic assembly at neuromuscular junction [GO:0045886]; neuron projection morphogenesis [GO:0048812]; positive regulation of endocytosis [GO:0045807]; positive regulation of hippo signaling [GO:0035332]; protein phosphorylation [GO:0006468]; R8 cell fate commitment [GO:0007460]; regulation of MAPK cascade [GO:0043408]; response to cocaine [GO:0042220]; response to ethanol [GO:0045471]; response to nicotine [GO:0035094]; tissue homeostasis [GO:0001894] GO:0000165; GO:0001894; GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0005819; GO:0005874; GO:0005886; GO:0005938; GO:0006468; GO:0006915; GO:0007460; GO:0016020; GO:0016319; GO:0030424; GO:0030514; GO:0030707; GO:0035094; GO:0035332; GO:0035556; GO:0036335; GO:0042220; GO:0043204; GO:0043408; GO:0045178; GO:0045471; GO:0045807; GO:0045886; GO:0046621; GO:0048036; GO:0048812; GO:0106310 9606 XM_044325546.1 0 35 200 46 49 NA NA NA NA NA NA 9607 XM_029347106.2 2059 1713 859 2052 1382 Q14117 0 Dihydropyrimidinase (DHP) (DHPase) (EC 3.5.2.2) (Dihydropyrimidine amidohydrolase) (Hydantoinase) Homo sapiens (Human) CMP catabolic process [GO:0006248]; dCMP catabolic process [GO:0006249]; dUMP catabolic process [GO:0046079]; pyrimidine nucleobase catabolic process [GO:0006208]; thymine catabolic process [GO:0006210]; UMP catabolic process [GO:0046050]; uracil catabolic process [GO:0006212] GO:0004157; GO:0005829; GO:0006208; GO:0006210; GO:0006212; GO:0006248; GO:0006249; GO:0008270; GO:0042802; GO:0046050; GO:0046079; GO:0051219; GO:0070062 9608 XR_003824917.2 157 95 78 151 222 NA NA NA NA NA NA 9609 XM_029357893.2 6 72 40 167 82 NA NA NA NA NA NA 9610 XM_029349285.2 70 14 0 20 51 P57788 1.07e-42 Monocarboxylate transporter 4 (MCT 4) (Solute carrier family 16 member 3) Gallus gallus (Chicken) lactate transmembrane transport [GO:0035873]; pyruvate transmembrane transport [GO:1901475] GO:0005886; GO:0015650; GO:0016323; GO:0035873; GO:0050833; GO:1901475 9611 XR_006393555.1 9 4 19 12 25 NA NA NA NA NA NA 9612 XM_044313325.1 0 0 8 0 10 Q9EQD2 9.28e-44 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 9613 XM_044314286.1 36 8 22 17 27 Q3UQ28 3.16e-32 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 9614 XM_044314286.1 36 8 22 17 27 Q3UQ28 3.58e-28 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 9615 XM_029355135.2 5811 3646 3108 7994 5269 P18654 0 Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (p90RSK3) (MAP kinase-activated protein kinase 1b) (MAPK-activated protein kinase 1b) (MAPKAP kinase 1b) (MAPKAPK-1b) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) Mus musculus (Mouse) cell cycle [GO:0007049]; intracellular signal transduction [GO:0035556]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to lipopolysaccharide [GO:0032496]; toll-like receptor signaling pathway [GO:0002224] GO:0000287; GO:0002224; GO:0004674; GO:0004711; GO:0005524; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0007049; GO:0018105; GO:0019901; GO:0032496; GO:0035556; GO:0043027; GO:0043154; GO:0045944; GO:0106310 9616 XM_029352132.2 1631 1559 1210 1631 900 Q8N5I4 9.09e-84 Dehydrogenase/reductase SDR family member on chromosome X (EC 1.1.-.-) (DHRSXY) (Short chain dehydrogenase/reductase family 46C member 1) (Short chain dehydrogenase/reductase family 7C member 6) Homo sapiens (Human) positive regulation of autophagy [GO:0010508] GO:0005576; GO:0010508; GO:0016491 9617 XM_029358073.2 328 293 154 397 355 O75665 5.65e-48 Centriole and centriolar satellite protein OFD1 (Oral-facial-digital syndrome 1 protein) (Protein 71-7A) Homo sapiens (Human) cilium assembly [GO:0060271]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287] GO:0005576; GO:0005634; GO:0005813; GO:0005814; GO:0005829; GO:0005929; GO:0015630; GO:0016020; GO:0031514; GO:0034451; GO:0036064; GO:0042802; GO:0043014; GO:0043015; GO:0060271; GO:0060287 9618 XM_029332203.2 3237 1575 1827 2385 1978 A5A6P2 5.87e-140 Acid ceramidase (AC) (ACDase) (Acid CDase) (EC 3.5.1.23) (Acylsphingosine deacylase) (N-acylethanolamine hydrolase ASAH1) (EC 3.5.1.-) (N-acylsphingosine amidohydrolase) [Cleaved into: Acid ceramidase subunit alpha; Acid ceramidase subunit beta] Pan troglodytes (Chimpanzee) cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; ceramide catabolic process [GO:0046514]; fatty acid metabolic process [GO:0006631]; keratinocyte differentiation [GO:0030216]; regulation of programmed necrotic cell death [GO:0062098]; regulation of steroid biosynthetic process [GO:0050810]; sphingosine biosynthetic process [GO:0046512] GO:0005615; GO:0005764; GO:0006631; GO:0016810; GO:0017040; GO:0017064; GO:0030216; GO:0046512; GO:0046513; GO:0046514; GO:0050810; GO:0062098; GO:0071356; GO:0102121 9619 XM_044326324.1 98 57 20 336 102 NA NA NA NA NA NA 9620 XM_029354474.2 127 56 19 18 33 A4IGM4 4.26e-28 Hydroxysteroid 11-beta-dehydrogenase 1-like protein (EC 1.1.1.-) (11-beta-hydroxysteroid dehydrogenase type 3) (11-DH3) (11-beta-HSD3) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005576; GO:0016491 9621 XM_044327546.1 18 1 10 10 87 NA NA NA NA NA NA 9622 XM_044315033.1 41 0 31 41 155 NA NA NA NA NA NA 9623 XM_044325983.1 44 42 36 87 110 NA NA NA NA NA NA 9624 XM_029330362.2 920 945 484 970 1165 Q5ZKC1 0 Eukaryotic translation initiation factor 2A (eIF-2A) Gallus gallus (Chicken) regulation of translation [GO:0006417]; ribosome assembly [GO:0042255] GO:0000049; GO:0003729; GO:0003743; GO:0005737; GO:0005850; GO:0006417; GO:0022627; GO:0042255; GO:0043022 9625 XM_044311378.1 196 0 83 159 132 NA NA NA NA NA NA 9626 XM_029341564.2 639 556 298 580 1093 O43663 8.77e-109 Protein regulator of cytokinesis 1 Homo sapiens (Human) cell division [GO:0051301]; microtubule cytoskeleton organization [GO:0000226]; mitotic spindle elongation [GO:0000022]; mitotic spindle midzone assembly [GO:0051256]; positive regulation of cell population proliferation [GO:0008284]; regulation of cytokinesis [GO:0032465] GO:0000022; GO:0000226; GO:0000922; GO:0005634; GO:0005654; GO:0005694; GO:0005737; GO:0005819; GO:0005829; GO:0005876; GO:0005886; GO:0008017; GO:0008284; GO:0015630; GO:0019894; GO:0019901; GO:0030496; GO:0032465; GO:0042802; GO:0045171; GO:0051256; GO:0051301; GO:0070938; GO:1990023 9627 XM_029341895.2 75 185 55 148 154 B4DXR9 5.68e-38 Zinc finger protein 732 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0000978; GO:0000981; GO:0005634; GO:0006355; GO:0046872 9628 XM_029341895.2 75 185 55 148 154 B4DXR9 2.09e-36 Zinc finger protein 732 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0000978; GO:0000981; GO:0005634; GO:0006355; GO:0046872 9629 XM_029341895.2 75 185 55 148 154 B4DXR9 9.34e-30 Zinc finger protein 732 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0000978; GO:0000981; GO:0005634; GO:0006355; GO:0046872 9630 XM_029341895.2 75 185 55 148 154 B4DXR9 2.82e-28 Zinc finger protein 732 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0000978; GO:0000981; GO:0005634; GO:0006355; GO:0046872 9631 XM_029341895.2 75 185 55 148 154 B4DXR9 1.52e-22 Zinc finger protein 732 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0000978; GO:0000981; GO:0005634; GO:0006355; GO:0046872 9632 XM_029341895.2 75 185 55 148 154 B4DXR9 6.86e-21 Zinc finger protein 732 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0000978; GO:0000981; GO:0005634; GO:0006355; GO:0046872 9633 XM_044310157.1 110 58 90 23 33 Q96AY4 2.33e-99 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9634 XM_044310157.1 110 58 90 23 33 Q96AY4 4.24e-93 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9635 XM_044310157.1 110 58 90 23 33 Q96AY4 9.71e-93 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9636 XM_044310157.1 110 58 90 23 33 Q96AY4 1.54e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9637 XM_044310157.1 110 58 90 23 33 Q96AY4 1.08e-89 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9638 XM_044310157.1 110 58 90 23 33 Q96AY4 3.25e-85 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9639 XM_044310157.1 110 58 90 23 33 Q96AY4 4.93e-63 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9640 XM_044310157.1 110 58 90 23 33 Q96AY4 7.47e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9641 XM_044310157.1 110 58 90 23 33 Q96AY4 4.32e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9642 XM_044310157.1 110 58 90 23 33 Q96AY4 1.16e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9643 XR_006392181.1 48 12 73 98 90 NA NA NA NA NA NA 9644 XM_044324116.1 0 0 4 11 11 NA NA NA NA NA NA 9645 XM_044310465.1 34 0 0 67 0 NA NA NA NA NA NA 9646 XM_029350089.2 125 232 64 169 101 NA NA NA NA NA NA 9647 XM_044322867.1 1216 830 541 1481 896 Q9NZJ4 0 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 9648 XM_044322867.1 1216 830 541 1481 896 Q9NZJ4 1.01e-41 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 9649 XM_029347686.2 51 0 0 21 0 Q9EP89 4.67e-117 Serine beta-lactamase-like protein LACTB, mitochondrial (EC 3.4.-.-) Mus musculus (Mouse) lipid metabolic process [GO:0006629]; proteolysis [GO:0006508]; regulation of lipid metabolic process [GO:0019216] GO:0005739; GO:0005829; GO:0006508; GO:0006629; GO:0008233; GO:0019216; GO:0042802 9650 XM_044318743.1 104 64 22 45 129 Q76KP1 1.41e-63 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Homo sapiens (Human) NA GO:0008376; GO:0032580; GO:0033842 9651 XM_044318743.1 104 64 22 45 129 Q76KP1 3.58e-28 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Homo sapiens (Human) NA GO:0008376; GO:0032580; GO:0033842 9652 XR_006393107.1 7 13 13 9 22 Q6AYJ1 5.36e-124 ATP-dependent DNA helicase Q1 (EC 3.6.4.12) (DNA-dependent ATPase Q1) (RecQ protein-like 1) Rattus norvegicus (Rat) DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724] GO:0000724; GO:0003678; GO:0005524; GO:0005634; GO:0005694; GO:0005737; GO:0006268; GO:0006281; GO:0006310; GO:0009378; GO:0016887; GO:0032508; GO:0043138; GO:1990814 9653 XR_006393107.1 7 13 13 9 22 Q6AYJ1 5.36e-124 ATP-dependent DNA helicase Q1 (EC 3.6.4.12) (DNA-dependent ATPase Q1) (RecQ protein-like 1) Rattus norvegicus (Rat) DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724] GO:0000724; GO:0003678; GO:0005524; GO:0005634; GO:0005694; GO:0005737; GO:0006268; GO:0006281; GO:0006310; GO:0009378; GO:0016887; GO:0032508; GO:0043138; GO:1990814 9654 XM_029345197.2 2554 1823 2284 4332 2494 NA NA NA NA NA NA 9655 XR_003825891.2 58 3 59 30 270 NA NA NA NA NA NA 9656 XM_044318386.1 13 14 11 4 10 NA NA NA NA NA NA 9657 XM_044307255.1 48 4 3 25 0 NA NA NA NA NA NA 9658 XM_044326591.1 1126 883 370 1633 952 Q91285 2.28e-78 Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (PFR1) Pleurodeles waltl (Iberian ribbed newt) positive regulation of cell population proliferation [GO:0008284] GO:0005007; GO:0005524; GO:0005634; GO:0005829; GO:0005886; GO:0008284; GO:0031410 9659 XM_044307843.1 0 0 75 0 0 NA NA NA NA NA NA 9660 XM_029340555.2 4 14 0 4 2 NA NA NA NA NA NA 9661 XM_044315786.1 6 0 0 0 8 NA NA NA NA NA NA 9662 XM_044326938.1 200 72 93 0 264 NA NA NA NA NA NA 9663 XM_044314031.1 26 9 14 445 102 Q9BWT3 3.78e-147 Poly(A) polymerase gamma (PAP-gamma) (EC 2.7.7.19) (Neo-poly(A) polymerase) (Neo-PAP) (Polynucleotide adenylyltransferase gamma) (SRP RNA 3'-adenylating enzyme) (Signal recognition particle RNA-adenylating enzyme) (SRP RNA-adenylating enzyme) Homo sapiens (Human) mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631] GO:0003723; GO:0004652; GO:0005524; GO:0005634; GO:0005654; GO:0005829; GO:0006378; GO:0016020; GO:0016604; GO:0043631; GO:0046872 9664 XM_044314724.1 0 114 0 101 0 Q91VS8 1.11e-154 FERM, ARHGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR) (FERM, RhoGEF and pleckstrin domain-containing protein 2) Mus musculus (Mouse) actin cytoskeleton reorganization [GO:0031532]; cell adhesion [GO:0007155]; hair cycle process [GO:0022405]; neuron remodeling [GO:0016322]; osteoclast differentiation [GO:0030316]; podosome assembly [GO:0071800]; Rac protein signal transduction [GO:0016601]; regulation of integrin activation [GO:0033623]; semaphorin-plexin signaling pathway [GO:0071526] GO:0005085; GO:0005737; GO:0005829; GO:0005856; GO:0007155; GO:0008092; GO:0016322; GO:0016601; GO:0022405; GO:0030316; GO:0031532; GO:0033623; GO:0071526; GO:0071800 9665 XM_029356379.2 25 0 0 0 82 P04274 6.71e-26 Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor) Mesocricetus auratus (Golden hamster) activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; bone resorption [GO:0045453]; brown fat cell differentiation [GO:0050873]; cellular response to amyloid-beta [GO:1904646]; desensitization of G protein-coupled receptor signaling pathway by arrestin [GO:0002032]; diet induced thermogenesis [GO:0002024]; heat generation [GO:0031649]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of smooth muscle contraction [GO:0045986]; norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0002025]; positive regulation of AMPA receptor activity [GO:2000969]; positive regulation of autophagosome maturation [GO:1901098]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of lipophagy [GO:1904504]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mini excitatory postsynaptic potential [GO:0061885]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor-mediated endocytosis [GO:0006898]; regulation of sodium ion transport [GO:0002028]; response to cold [GO:0009409]; smooth muscle contraction [GO:0006939]; transcription by RNA polymerase II [GO:0006366] GO:0001540; GO:0002024; GO:0002025; GO:0002028; GO:0002032; GO:0004941; GO:0005634; GO:0005769; GO:0005794; GO:0006366; GO:0006898; GO:0006939; GO:0007189; GO:0007190; GO:0008179; GO:0009409; GO:0010739; GO:0015459; GO:0016324; GO:0030501; GO:0031649; GO:0040015; GO:0042803; GO:0043235; GO:0043410; GO:0044877; GO:0045453; GO:0045944; GO:0045986; GO:0050873; GO:0051380; GO:0061885; GO:0071902; GO:0098992; GO:0120162; GO:1901098; GO:1904504; GO:1904646; GO:2000969 9666 XM_044316838.1 9 10 13 34 17 NA NA NA NA NA NA 9667 XM_044311368.1 31 14 3 82 16 C3VPR6 2.97e-26 Protein NLRC5 Mus musculus (Mouse) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of type II interferon-mediated signaling pathway [GO:0060335]; regulation of kinase activity [GO:0043549]; response to bacterium [GO:0009617] GO:0000978; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0009617; GO:0032088; GO:0035556; GO:0043549; GO:0045087; GO:0045345; GO:0045944; GO:0051607; GO:0060335; GO:0060339; GO:0060340 9668 XR_003825200.2 11 0 14 8 18 NA NA NA NA NA NA 9669 XM_044308317.1 119 101 0 298 144 Q95YJ5 0 Thioredoxin domain-containing protein 3 homolog (Dynein intermediate chain 3) Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis) cell differentiation [GO:0030154]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside diphosphate phosphorylation [GO:0006165]; spermatogenesis [GO:0007283]; UTP biosynthetic process [GO:0006228] GO:0004550; GO:0006165; GO:0006183; GO:0006228; GO:0006241; GO:0007283; GO:0030154 9670 XM_044327634.1 14 32 2 19 0 NA NA NA NA NA NA 9671 XM_044319608.1 0 20 7 13 53 NA NA NA NA NA NA 9672 XR_006396496.1 8 2 0 4 36 NA NA NA NA NA NA 9673 XM_029325150.2 1405 800 662 1417 1207 Q07994 0 NADPH--cytochrome P450 reductase (CPR) (P450R) (EC 1.6.2.4) Musca domestica (House fly) NA GO:0003958; GO:0005789; GO:0010181; GO:0050660; GO:0050661 9674 XM_029334057.2 3819 8091 6398 6034 4508 NA NA NA NA NA NA 9675 XM_029352175.2 1336 1239 940 1807 2124 F1M5N7 0 Kinesin-like protein KIF21B Rattus norvegicus (Rat) brain development [GO:0007420]; corpus callosum development [GO:0022038]; microtubule-based movement [GO:0007018] GO:0003777; GO:0005524; GO:0005871; GO:0005874; GO:0007018; GO:0007420; GO:0008017; GO:0016887; GO:0022038; GO:0030425; GO:0030426; GO:0031410 9676 XM_029352175.2 1336 1239 940 1807 2124 F1M5N7 1.6e-93 Kinesin-like protein KIF21B Rattus norvegicus (Rat) brain development [GO:0007420]; corpus callosum development [GO:0022038]; microtubule-based movement [GO:0007018] GO:0003777; GO:0005524; GO:0005871; GO:0005874; GO:0007018; GO:0007420; GO:0008017; GO:0016887; GO:0022038; GO:0030425; GO:0030426; GO:0031410 9677 XM_029324103.2 225 63 217 11 1 NA NA NA NA NA NA 9678 XR_006393395.1 62 17 76 40 393 NA NA NA NA NA NA 9679 XR_006396868.1 0 3 15 9 7 NA NA NA NA NA NA 9680 XM_044319254.1 139 22 83 79 63 NA NA NA NA NA NA 9681 XM_044320875.1 0 659 188 443 48 NA NA NA NA NA NA 9682 XM_029328292.2 0 0 31 0 53 NA NA NA NA NA NA 9683 XM_044310815.1 96 74 20 79 80 P0CT39 5.41e-88 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 9684 XM_029326959.2 47 8 33 20 110 P48733 5.01e-24 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Bos taurus (Bovine) antibacterial innate immune response [GO:0140367]; defense response to Gram-negative bacterium [GO:0050829] GO:0000922; GO:0005201; GO:0005509; GO:0005576; GO:0005929; GO:0016020; GO:0016323; GO:0016324; GO:0031012; GO:0050829; GO:0060170; GO:0140367 9685 XM_029338262.2 14 0 140 19 4 NA NA NA NA NA NA 9686 XM_029336644.2 25 1 26 17 81 P48040 2.26e-33 Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor) Ovis aries (Sheep) NA GO:0005886; GO:0008502 9687 XM_029333226.2 0 0 0 9 0 O75899 1.42e-91 Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51) (HG20) Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway [GO:0007186]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; neuron-glial cell signaling [GO:0150099]; synaptic transmission, GABAergic [GO:0051932] GO:0004888; GO:0004965; GO:0005737; GO:0005886; GO:0007186; GO:0007193; GO:0007194; GO:0007214; GO:0007268; GO:0038039; GO:0043005; GO:0045211; GO:0046982; GO:0051932; GO:0150099; GO:1902710; GO:1902712 9688 XM_044327331.1 0 0 2 14 7 NA NA NA NA NA NA 9689 XM_044318377.1 1 11 6 10 49 B0BN95 1.79e-32 Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease) Rattus norvegicus (Rat) NA GO:0004518; GO:0005634; GO:0005737; GO:0046872 9690 XM_044309998.1 7 0 0 7 0 NA NA NA NA NA NA 9691 XM_044319601.1 23 6 22 33 9 NA NA NA NA NA NA 9692 XM_044311776.1 12 1 30 34 40 B8VIU6 1.1e-41 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 9693 XM_029344689.2 562 492 356 685 773 Q921N6 1.76e-174 Probable ATP-dependent RNA helicase DDX27 (EC 3.6.4.13) (DEAD box protein 27) Mus musculus (Mouse) rRNA processing [GO:0006364] GO:0003676; GO:0003724; GO:0005524; GO:0005694; GO:0005730; GO:0006364; GO:0016887 9694 XM_029335149.2 786 533 505 725 757 P0C8Z3 0 Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.4.19.12) (Deubiquitinating enzyme 22) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) Bos taurus (Bovine) cell cycle [GO:0007049]; chromatin organization [GO:0006325]; histone H3 acetylation [GO:0043966]; histone ubiquitination [GO:0016574]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; positive regulation of mitotic cell cycle [GO:0045931]; regulation of transcription by RNA polymerase II [GO:0006357]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000124; GO:0004843; GO:0005634; GO:0006325; GO:0006357; GO:0006511; GO:0007049; GO:0008270; GO:0010485; GO:0016574; GO:0019899; GO:0030374; GO:0035522; GO:0043966; GO:0045931 9695 XM_044327749.1 40 72 29 171 95 Q05609 2.92e-25 Serine/threonine-protein kinase CTR1 (EC 2.7.11.1) (Protein CONSTITUTIVE TRIPLE RESPONSE1) Arabidopsis thaliana (Mouse-ear cress) ethylene-activated signaling pathway [GO:0009873]; gibberellin biosynthetic process [GO:0009686]; negative regulation of ethylene-activated signaling pathway [GO:0010105]; protein autophosphorylation [GO:0046777]; regulation of post-embryonic root development [GO:2000069]; regulation of stem cell division [GO:2000035]; regulation of timing of transition from vegetative to reproductive phase [GO:0048510]; response to ethylene [GO:0009723]; response to fructose [GO:0009750]; response to hypoxia [GO:0001666]; response to sucrose [GO:0009744]; sugar mediated signaling pathway [GO:0010182] GO:0001666; GO:0004674; GO:0004712; GO:0005524; GO:0005789; GO:0009686; GO:0009723; GO:0009744; GO:0009750; GO:0009873; GO:0010105; GO:0010182; GO:0046777; GO:0048510; GO:0106310; GO:2000035; GO:2000069 9696 XM_029358100.2 336 438 295 261 226 B2RYR0 1.67e-34 E3 ubiquitin-protein ligase RNF168 (EC 2.3.2.27) (RING finger protein 168) (RING-type E3 ubiquitin transferase RNF168) Rattus norvegicus (Rat) cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; chromatin organization [GO:0006325]; double-strand break repair [GO:0006302]; histone H2A K63-linked ubiquitination [GO:0070535]; histone H2A monoubiquitination [GO:0035518]; histone H2A-K13 ubiquitination [GO:0036351]; histone H2A-K15 ubiquitination [GO:0036352]; isotype switching [GO:0045190]; negative regulation of transcription elongation by RNA polymerase II [GO:0034244]; positive regulation of DNA repair [GO:0045739]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; regulation of protein localization [GO:0032880]; response to ionizing radiation [GO:0010212]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000151; GO:0003682; GO:0004842; GO:0005634; GO:0006302; GO:0006325; GO:0006511; GO:0006974; GO:0010212; GO:0016567; GO:0031491; GO:0032880; GO:0032991; GO:0034244; GO:0034644; GO:0035518; GO:0035861; GO:0036351; GO:0036352; GO:0042393; GO:0043130; GO:0045190; GO:0045739; GO:0046872; GO:0070530; GO:0070534; GO:0070535; GO:1990391 9697 XM_029341921.2 89 97 28 89 63 P97677 1.02e-83 Delta-like protein 1 (Drosophila Delta homolog 1) (Delta1) Rattus norvegicus (Rat) astrocyte development [GO:0014002]; auditory receptor cell fate commitment [GO:0009912]; cell fate determination [GO:0001709]; cell-cell signaling [GO:0007267]; cerebellar molecular layer formation [GO:0021688]; cerebellar Purkinje cell layer structural organization [GO:0021693]; clathrin-dependent endocytosis [GO:0072583]; compartment pattern specification [GO:0007386]; determination of left/right symmetry [GO:0007368]; endothelial tip cell fate specification [GO:0097102]; energy homeostasis [GO:0097009]; heart looping [GO:0001947]; inhibition of neuroepithelial cell differentiation [GO:0002085]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear development [GO:0048839]; lateral inhibition [GO:0046331]; left/right axis specification [GO:0070986]; loop of Henle development [GO:0072070]; marginal zone B cell differentiation [GO:0002315]; myeloid cell differentiation [GO:0030099]; negative regulation of cardiac muscle cell differentiation [GO:2000726]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal cell differentiation [GO:0045605]; negative regulation of epithelial cell differentiation [GO:0030857]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of inner ear auditory receptor cell differentiation [GO:0045608]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of Notch signaling pathway [GO:0045746]; nephron development [GO:0072006]; nervous system development [GO:0007399]; neuroepithelial cell differentiation [GO:0060563]; neuron differentiation [GO:0030182]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; Notch signaling pathway involved in arterial endothelial cell fate commitment [GO:0060853]; organ growth [GO:0035265]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endocytosis [GO:0045807]; positive regulation of gene expression [GO:0010628]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of skeletal muscle tissue growth [GO:0048633]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proximal tubule development [GO:0072014]; proximal/distal pattern formation [GO:0009954]; regulation of blood pressure [GO:0008217]; regulation of cell adhesion [GO:0030155]; regulation of cell division [GO:0051302]; regulation of growth [GO:0040008]; regulation of neurogenesis [GO:0050767]; regulation of skeletal muscle tissue growth [GO:0048631]; regulation of somitogenesis [GO:0014807]; regulation of vascular endothelial growth factor signaling pathway [GO:1900746]; retina development in camera-type eye [GO:0060041]; retina morphogenesis in camera-type eye [GO:0060042]; skeletal muscle tissue growth [GO:0048630]; skin epidermis development [GO:0098773]; somite specification [GO:0001757]; somitogenesis [GO:0001756]; spinal cord development [GO:0021510]; type B pancreatic cell development [GO:0003323] GO:0001709; GO:0001756; GO:0001757; GO:0001947; GO:0002085; GO:0002315; GO:0003323; GO:0005112; GO:0005509; GO:0005886; GO:0005912; GO:0007219; GO:0007267; GO:0007368; GO:0007386; GO:0007399; GO:0008217; GO:0008284; GO:0008285; GO:0009912; GO:0009954; GO:0010628; GO:0014002; GO:0014807; GO:0016324; GO:0021510; GO:0021688; GO:0021693; GO:0030099; GO:0030155; GO:0030182; GO:0030857; GO:0030957; GO:0031410; GO:0032693; GO:0034351; GO:0035265; GO:0040008; GO:0042491; GO:0045121; GO:0045596; GO:0045605; GO:0045608; GO:0045638; GO:0045662; GO:0045665; GO:0045746; GO:0045747; GO:0045807; GO:0045944; GO:0046331; GO:0048018; GO:0048630; GO:0048631; GO:0048633; GO:0048665; GO:0048839; GO:0050767; GO:0051302; GO:0060041; GO:0060042; GO:0060563; GO:0060853; GO:0070986; GO:0072006; GO:0072014; GO:0072070; GO:0072583; GO:0097009; GO:0097102; GO:0097110; GO:0097150; GO:0098773; GO:1900746; GO:1903672; GO:2000726 9698 XR_006393522.1 85 67 36 170 77 NA NA NA NA NA NA 9699 XM_029327628.2 15 6 23 51 54 O60290 2.07e-61 Zinc finger protein 862 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006355; GO:0046872; GO:0046983 9700 XM_044328387.1 45 139 30 80 97 Q8K2J9 3.13e-78 BTB/POZ domain-containing protein 6 Mus musculus (Mouse) neurogenesis [GO:0022008] GO:0005829; GO:0022008 9701 XM_029348177.2 1298 493 224 358 90 O75581 0 Low-density lipoprotein receptor-related protein 6 (LRP-6) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; chemical synaptic transmission [GO:0007268]; dopaminergic neuron differentiation [GO:0071542]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001933; GO:0005041; GO:0005102; GO:0005109; GO:0005576; GO:0005783; GO:0005886; GO:0006469; GO:0007204; GO:0007268; GO:0009986; GO:0014029; GO:0014033; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0031410; GO:0031901; GO:0034392; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043434; GO:0044335; GO:0044340; GO:0045121; GO:0045202; GO:0045787; GO:0045893; GO:0045944; GO:0051091; GO:0060070; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072659; GO:0090118; GO:0090244; GO:0098609; GO:1904928; GO:1904948; GO:1904953; GO:1990851; GO:1990909 9702 XM_029348177.2 1298 493 224 358 90 O75581 8.71e-172 Low-density lipoprotein receptor-related protein 6 (LRP-6) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; chemical synaptic transmission [GO:0007268]; dopaminergic neuron differentiation [GO:0071542]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001933; GO:0005041; GO:0005102; GO:0005109; GO:0005576; GO:0005783; GO:0005886; GO:0006469; GO:0007204; GO:0007268; GO:0009986; GO:0014029; GO:0014033; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0031410; GO:0031901; GO:0034392; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043434; GO:0044335; GO:0044340; GO:0045121; GO:0045202; GO:0045787; GO:0045893; GO:0045944; GO:0051091; GO:0060070; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072659; GO:0090118; GO:0090244; GO:0098609; GO:1904928; GO:1904948; GO:1904953; GO:1990851; GO:1990909 9703 XM_029348177.2 1298 493 224 358 90 O75581 8.99e-89 Low-density lipoprotein receptor-related protein 6 (LRP-6) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; chemical synaptic transmission [GO:0007268]; dopaminergic neuron differentiation [GO:0071542]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001933; GO:0005041; GO:0005102; GO:0005109; GO:0005576; GO:0005783; GO:0005886; GO:0006469; GO:0007204; GO:0007268; GO:0009986; GO:0014029; GO:0014033; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0031410; GO:0031901; GO:0034392; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043434; GO:0044335; GO:0044340; GO:0045121; GO:0045202; GO:0045787; GO:0045893; GO:0045944; GO:0051091; GO:0060070; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072659; GO:0090118; GO:0090244; GO:0098609; GO:1904928; GO:1904948; GO:1904953; GO:1990851; GO:1990909 9704 XM_029349722.2 0 44 29 194 0 Q9J569 3.11e-25 Putative ankyrin repeat protein FPV162 Fowlpox virus (strain NVSL) (FPV) NA NA 9705 XM_044316285.1 81 5 52 20 99 NA NA NA NA NA NA 9706 XR_003824195.1 8 20 9 20 8 NA NA NA NA NA NA 9707 XM_029353312.2 6 0 0 13 7 P51954 7.45e-88 Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase 1) (NimA-related protein kinase 1) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; cilium assembly [GO:0060271]; kidney development [GO:0001822]; multicellular organism growth [GO:0035264]; protein phosphorylation [GO:0006468]; regulation of DNA damage checkpoint [GO:2000001]; response to ionizing radiation [GO:0010212]; spermatogenesis [GO:0007283] GO:0000242; GO:0001822; GO:0004672; GO:0004674; GO:0004713; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0005829; GO:0006468; GO:0006974; GO:0007049; GO:0007283; GO:0010212; GO:0016301; GO:0034451; GO:0035264; GO:0046872; GO:0051301; GO:0060271; GO:0071889; GO:0106310; GO:2000001 9708 XR_006392559.1 37 19 69 36 223 NA NA NA NA NA NA 9709 XM_029339714.2 427 503 293 344 346 Q3TXU5 3.83e-175 Deoxyhypusine synthase (DHS) (EC 2.5.1.46) Mus musculus (Mouse) glucose homeostasis [GO:0042593]; peptidyl-lysine modification to peptidyl-hypusine [GO:0008612]; positive regulation of T cell proliferation [GO:0042102]; spermidine catabolic process [GO:0046203]; spermidine metabolic process [GO:0008216] GO:0005737; GO:0008216; GO:0008612; GO:0034038; GO:0042102; GO:0042593; GO:0042802; GO:0046203 9710 XM_044319155.1 29 4 53 11 14 NA NA NA NA NA NA 9711 XM_044323173.1 6 10 7 24 8 NA NA NA NA NA NA 9712 XR_006393153.1 136 0 54 61 6 NA NA NA NA NA NA 9713 XM_029327972.2 18 0 3 4 16 Q96AY4 1.21e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9714 XM_044319023.1 1888 2330 2690 1631 1294 NA NA NA NA NA NA 9715 XM_029343255.2 6109 5762 3831 5572 7173 Q0MQI7 1.21e-119 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (EC 7.1.1.2) (NADH-ubiquinone oxidoreductase 24 kDa subunit) Pongo pygmaeus (Bornean orangutan) NA GO:0005743; GO:0008137; GO:0046872; GO:0051537; GO:0070469 9716 XR_006395955.1 148 83 54 67 119 NA NA NA NA NA NA 9717 XM_029355262.2 51 5 66 44 239 NA NA NA NA NA NA 9718 XM_029350564.2 1687 2219 1316 2254 1687 P69525 8.13e-78 Transmembrane protease serine 9 (EC 3.4.21.-) (Polyserase-I) (Polyserine protease 1) (Polyserase-1) [Cleaved into: Serase-1; Serase-2; Serase-3] Mus musculus (Mouse) plasminogen activation [GO:0031639]; proteolysis [GO:0006508] GO:0004252; GO:0005886; GO:0006508; GO:0008236; GO:0031639 9719 XM_029350564.2 1687 2219 1316 2254 1687 P69525 3.72e-37 Transmembrane protease serine 9 (EC 3.4.21.-) (Polyserase-I) (Polyserine protease 1) (Polyserase-1) [Cleaved into: Serase-1; Serase-2; Serase-3] Mus musculus (Mouse) plasminogen activation [GO:0031639]; proteolysis [GO:0006508] GO:0004252; GO:0005886; GO:0006508; GO:0008236; GO:0031639 9720 XM_029350564.2 1687 2219 1316 2254 1687 P69525 3.04e-35 Transmembrane protease serine 9 (EC 3.4.21.-) (Polyserase-I) (Polyserine protease 1) (Polyserase-1) [Cleaved into: Serase-1; Serase-2; Serase-3] Mus musculus (Mouse) plasminogen activation [GO:0031639]; proteolysis [GO:0006508] GO:0004252; GO:0005886; GO:0006508; GO:0008236; GO:0031639 9721 XM_029350564.2 1687 2219 1316 2254 1687 P69525 1.98e-34 Transmembrane protease serine 9 (EC 3.4.21.-) (Polyserase-I) (Polyserine protease 1) (Polyserase-1) [Cleaved into: Serase-1; Serase-2; Serase-3] Mus musculus (Mouse) plasminogen activation [GO:0031639]; proteolysis [GO:0006508] GO:0004252; GO:0005886; GO:0006508; GO:0008236; GO:0031639 9722 XM_029350564.2 1687 2219 1316 2254 1687 P69525 9.59e-33 Transmembrane protease serine 9 (EC 3.4.21.-) (Polyserase-I) (Polyserine protease 1) (Polyserase-1) [Cleaved into: Serase-1; Serase-2; Serase-3] Mus musculus (Mouse) plasminogen activation [GO:0031639]; proteolysis [GO:0006508] GO:0004252; GO:0005886; GO:0006508; GO:0008236; GO:0031639 9723 XM_029347405.2 267 154 182 205 266 Q06442 7.83e-85 Protein Wnt-5a Ambystoma mexicanum (Axolotl) anatomical structure development [GO:0048856]; Wnt signaling pathway [GO:0016055] GO:0005102; GO:0005576; GO:0016055; GO:0048856 9724 XM_044327808.1 104 131 127 229 306 NA NA NA NA NA NA 9725 XM_044314877.1 1144 402 7 418 607 NA NA NA NA NA NA 9726 XM_029345859.2 164 84 82 53 148 P79942 7.75e-74 Nocturnin (EC 3.1.3.-) (Carbon catabolite repression 4-like protein) (Rhythmic message 1) (RM1) Xenopus laevis (African clawed frog) circadian rhythm [GO:0007623]; NADP metabolic process [GO:0006739] GO:0004535; GO:0005634; GO:0005739; GO:0006739; GO:0007623; GO:0019178; GO:0046872; GO:0048471; GO:0102757 9727 XM_044314849.1 330 324 157 272 141 Q969V4 1.18e-140 Tektin-1 Homo sapiens (Human) cilium assembly [GO:0060271]; cilium movement involved in cell motility [GO:0060294] GO:0005634; GO:0005879; GO:0015630; GO:0031514; GO:0060271; GO:0060294 9728 XR_006395683.1 146 113 94 202 50 NA NA NA NA NA NA 9729 XM_044314083.1 0 2 0 0 55 NA NA NA NA NA NA 9730 XM_044325470.1 73 15 172 0 194 NA NA NA NA NA NA 9731 XM_029346271.2 1330 593 977 1668 1561 A3C6D7 6.35e-75 Actin-2 (EC 3.6.4.-) Oryza sativa subsp. japonica (Rice) NA GO:0005524; GO:0005737; GO:0005856; GO:0016787 9732 XM_044328251.1 35 2 36 7 128 NA NA NA NA NA NA 9733 XM_029331831.2 248 226 495 548 481 Q6GLJ6 1.42e-21 PDZ and LIM domain protein 3 Xenopus laevis (African clawed frog) NA GO:0030018; GO:0046872 9734 XM_029332993.2 0 0 22 0 0 Q3UZD5 1.63e-97 Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.361) (PR domain zinc finger protein 6) (PR domain-containing protein 6) (PR domain-containing protein in smooth muscle) Mus musculus (Mouse) chromatin organization [GO:0006325]; histone methylation [GO:0016571]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of smooth muscle cell differentiation [GO:0051151]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of gene expression [GO:0010468] GO:0000122; GO:0005634; GO:0006325; GO:0010468; GO:0016571; GO:0022008; GO:0042802; GO:0045892; GO:0046872; GO:0051151; GO:0140944 9735 XM_044316298.1 9 12 44 0 32 P0CT39 4.92e-87 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 9736 XM_044310372.1 52 2 37 33 141 NA NA NA NA NA NA 9737 XM_029340280.2 7 89 42 26 24 Q5RA50 9.87e-26 Protein FAM124A Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA NA 9738 XM_044308567.1 3 0 6 9 18 NA NA NA NA NA NA 9739 XM_044322050.1 0 38 43 0 7 Q8IS64 2.66e-158 Endothelin-converting enzyme homolog (ECE) (EC 3.4.24.-) Locusta migratoria (Migratory locust) proteolysis [GO:0006508] GO:0004175; GO:0004222; GO:0005886; GO:0006508; GO:0008270 9740 XM_029340625.2 228 0 0 383 437 Q7Z5V6 3.96e-68 Protein phosphatase 1 regulatory subunit 32 Homo sapiens (Human) NA GO:0005737; GO:0019902; GO:0036064 9741 XM_044309157.1 2 5 10 6 37 NA NA NA NA NA NA 9742 XM_044315754.1 0 0 35 0 54 NA NA NA NA NA NA 9743 XM_029334696.2 752 360 257 497 646 Q9R1S8 0 Calpain-7 (EC 3.4.22.-) (PalB homolog) (PalBH) Mus musculus (Mouse) positive regulation of epithelial cell migration [GO:0010634]; proteolysis [GO:0006508]; self proteolysis [GO:0097264] GO:0004175; GO:0004197; GO:0004198; GO:0005634; GO:0005813; GO:0005829; GO:0006508; GO:0010634; GO:0090541; GO:0097264 9744 XM_029325588.2 196 2 0 169 137 Q8AWB5 1.84e-101 Alpha-(1,3)-fucosyltransferase 10 (EC 2.4.1.-) (Fucosyltransferase X) (Fuc-TX) (FucT-X) (Galactoside 3-L-fucosyltransferase 10) (Fucosyltransferase 10) Gallus gallus (Chicken) protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0032580; GO:0046920 9745 XR_003827001.2 210 44 46 69 179 NA NA NA NA NA NA 9746 XR_003828621.2 20 7 0 5 6 NA NA NA NA NA NA 9747 XM_029326478.2 142 67 46 134 113 Q12893 2.45e-76 Transmembrane protein 115 (Placental protein 6) (Protein PL6) Homo sapiens (Human) negative regulation of cell population proliferation [GO:0008285]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] GO:0000139; GO:0005634; GO:0005794; GO:0006890; GO:0008285; GO:0015031; GO:0032580; GO:0042802 9748 XM_029331201.2 0 0 0 0 7 O62714 1.56e-96 Extracellular calcium-sensing receptor (CaSR) (Parathyroid cell calcium-sensing receptor) (PCaR1) Sus scrofa (Pig) cellular calcium ion homeostasis [GO:0006874]; detection of calcium ion [GO:0005513]; G protein-coupled receptor signaling pathway [GO:0007186]; regulation of calcium ion transport [GO:0051924] GO:0004930; GO:0005509; GO:0005513; GO:0005886; GO:0006874; GO:0007186; GO:0016597; GO:0042803; GO:0051924 9749 XM_029338678.2 168 95 67 57 241 Q91YL3 0 Uridine-cytidine kinase-like 1 (EC 2.7.1.48) Mus musculus (Mouse) phosphorylation [GO:0016310]; UMP salvage [GO:0044206] GO:0004849; GO:0005524; GO:0005634; GO:0005737; GO:0016310; GO:0044206 9750 XM_029340191.2 0 0 0 31 10 Q05096 0 Unconventional myosin-Ib (Myosin I alpha) (MMI-alpha) (MMIa) (Myosin heavy chain myr 1) Rattus norvegicus (Rat) actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; actin filament-based movement [GO:0030048]; nervous system development [GO:0007399]; post-Golgi vesicle-mediated transport [GO:0006892]; transferrin transport [GO:0033572]; vesicle transport along actin filament [GO:0030050] GO:0000146; GO:0003774; GO:0003779; GO:0005516; GO:0005524; GO:0005546; GO:0005547; GO:0005737; GO:0005769; GO:0005884; GO:0005886; GO:0005902; GO:0005903; GO:0006892; GO:0007015; GO:0007399; GO:0010008; GO:0015629; GO:0016459; GO:0030048; GO:0030050; GO:0030175; GO:0031982; GO:0032588; GO:0033572; GO:0045177; GO:0048471; GO:0051015; GO:0051017; GO:0071944 9751 XM_044322889.1 737 529 399 795 690 Q96GM5 0 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 (60 kDa BRG-1/Brm-associated factor subunit A) (BRG1-associated factor 60A) (BAF60A) (SWI/SNF complex 60 kDa subunit) Homo sapiens (Human) cellular response to fatty acid [GO:0071398]; chromatin remodeling [GO:0006338]; negative regulation of cell differentiation [GO:0045596]; nervous system development [GO:0007399]; nucleosome disassembly [GO:0006337]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of T cell differentiation [GO:0045582]; regulation of G0 to G1 transition [GO:0070316]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of nucleotide-excision repair [GO:2000819]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription initiation-coupled chromatin remodeling [GO:0045815] GO:0000776; GO:0000785; GO:0003682; GO:0003712; GO:0003713; GO:0005102; GO:0005634; GO:0005654; GO:0006337; GO:0006338; GO:0006357; GO:0007399; GO:0008284; GO:0016363; GO:0016514; GO:0016586; GO:0030071; GO:0035060; GO:0043231; GO:0045582; GO:0045596; GO:0045597; GO:0045663; GO:0045815; GO:0060090; GO:0070316; GO:0071398; GO:0071564; GO:0071565; GO:0140288; GO:1902459; GO:2000045; GO:2000781; GO:2000819 9752 XR_003826597.2 415 41 46 719 1 NA NA NA NA NA NA 9753 XM_029352298.2 1259 1830 1043 1237 734 O24466 6.74e-46 Ras-related protein RABE1a (AtRABE1a) (Ras-related protein Rab8B) (AtRab8B) Arabidopsis thaliana (Mouse-ear cress) protein secretion [GO:0009306]; regulation of exocytosis [GO:0017157]; vesicle docking involved in exocytosis [GO:0006904] GO:0000139; GO:0003924; GO:0005525; GO:0005886; GO:0006904; GO:0009306; GO:0017157; GO:0043231 9754 XM_029338454.2 0 0 0 0 8 Q1JQC1 4.73e-33 Major facilitator superfamily domain-containing protein 1 Bos taurus (Bovine) protein localization to lysosome [GO:0061462]; protein stabilization [GO:0050821] GO:0005764; GO:0005765; GO:0022857; GO:0042803; GO:0050821; GO:0061462 9755 XM_029338454.2 0 0 0 0 8 Q1JQC1 4.73e-33 Major facilitator superfamily domain-containing protein 1 Bos taurus (Bovine) protein localization to lysosome [GO:0061462]; protein stabilization [GO:0050821] GO:0005764; GO:0005765; GO:0022857; GO:0042803; GO:0050821; GO:0061462 9756 XM_029326860.2 167 0 120 0 348 F8J3H2 4.82e-23 NA NA NA NA 9757 XM_029347627.2 743 617 490 1169 752 NA NA NA NA NA NA 9758 XM_029350234.2 274 734 265 419 584 NA NA NA NA NA NA 9759 XM_044322386.1 11 8 28 18 22 NA NA NA NA NA NA 9760 XM_044321813.1 43 141 66 157 98 NA NA NA NA NA NA 9761 XM_029349422.2 1047 1549 838 948 725 Q9XVI9 4.16e-32 Myosin-2 essential light chain Caenorhabditis elegans mitotic cytokinesis [GO:0000281] GO:0000281; GO:0005509; GO:0005737; GO:0015629; GO:0016460 9762 XM_044308106.1 0 52 20 17 12 NA NA NA NA NA NA 9763 XR_006396605.1 19 37 35 63 37 NA NA NA NA NA NA 9764 XM_029348805.2 0 46 0 188 168 NA NA NA NA NA NA 9765 XR_003828261.2 4 4 6 11 13 Q8VD72 0 Tetratricopeptide repeat protein 8 (TPR repeat protein 8) (Bardet-Biedl syndrome 8 protein homolog) Mus musculus (Mouse) axon guidance [GO:0007411]; camera-type eye photoreceptor cell differentiation [GO:0060219]; cilium assembly [GO:0060271]; establishment of anatomical structure orientation [GO:0048560]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of planar polarity [GO:0001736]; fat cell differentiation [GO:0045444]; inner ear receptor cell stereocilium organization [GO:0060122]; multi-ciliated epithelial cell differentiation [GO:1903251]; multicellular organism growth [GO:0035264]; negative regulation of GTPase activity [GO:0034260]; non-motile cilium assembly [GO:1905515]; olfactory bulb development [GO:0021772]; protein localization to plasma membrane [GO:0072659]; protein transport [GO:0015031]; regulation of protein localization [GO:0032880]; regulation of stress fiber assembly [GO:0051492]; renal tubule development [GO:0061326]; sensory perception of smell [GO:0007608] GO:0001736; GO:0005737; GO:0005813; GO:0005814; GO:0005929; GO:0007411; GO:0007608; GO:0015031; GO:0016020; GO:0021772; GO:0032391; GO:0032880; GO:0034260; GO:0034464; GO:0035264; GO:0036064; GO:0045198; GO:0045444; GO:0048560; GO:0051492; GO:0060122; GO:0060170; GO:0060219; GO:0060271; GO:0061326; GO:0061629; GO:0072659; GO:0097730; GO:1903251; GO:1905515 9766 XM_044314179.1 20 16 4 0 16 NA NA NA NA NA NA 9767 XM_044315409.1 113 30 40 173 234 NA NA NA NA NA NA 9768 XM_029341651.2 41828 44730 7754 35728 10777 A8WG21 2.6e-23 Sorting nexin-10B Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; intracellular protein transport [GO:0006886]; vesicle organization [GO:0016050] GO:0005768; GO:0006886; GO:0010008; GO:0016050; GO:0060271; GO:1901981 9769 XM_044312413.1 67 26 3 0 9 NA NA NA NA NA NA 9770 XM_044327852.1 219 165 408 256 506 NA NA NA NA NA NA 9771 XM_029344642.2 0 0 0 12 0 Q5R5U3 4.84e-104 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 9772 XM_029344642.2 0 0 0 12 0 Q5R5U3 1.64e-99 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 9773 XM_029344642.2 0 0 0 12 0 Q5R5U3 2.66e-45 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 9774 XM_029344642.2 0 0 0 12 0 Q5R5U3 9.69e-32 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 9775 XM_044308655.1 824 273 204 457 806 Q95LI2 2.58e-30 Vitrin Bos taurus (Bovine) spinal cord development [GO:0021510] GO:0005576; GO:0021510 9776 XR_006396818.1 4 0 0 0 23 NA NA NA NA NA NA 9777 XM_044317939.1 34 78 23 18 19 Q8K430 8.95e-37 Kelch-like protein 17 (Actinfilin) Rattus norvegicus (Rat) actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; protein ubiquitination [GO:0016567]; regulation protein catabolic process at postsynapse [GO:0140252] GO:0007420; GO:0014069; GO:0015629; GO:0016567; GO:0030036; GO:0031208; GO:0032839; GO:0043025; GO:0051015; GO:0060090; GO:0098794; GO:0098978; GO:0140252 9778 XM_044310555.1 232 192 32 47 6 Q7RTR2 2.39e-36 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 9779 XM_044310555.1 232 192 32 47 6 Q7RTR2 9.36e-31 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 9780 XM_029332119.2 262 124 192 142 357 Q5SQN1 4.53e-34 Synaptosomal-associated protein 47 (SNAP-47) (Epididymis luminal protein 170) (Synaptosomal-associated 47 kDa protein) Homo sapiens (Human) exocytosis [GO:0006887]; synaptic vesicle fusion to presynaptic active zone membrane [GO:0031629]; synaptic vesicle priming [GO:0016082]; vesicle fusion [GO:0006906] GO:0005484; GO:0005886; GO:0006887; GO:0006906; GO:0012505; GO:0016082; GO:0019905; GO:0031201; GO:0031629; GO:0048471; GO:0098793 9781 XM_029357159.2 7 0 0 0 0 NA NA NA NA NA NA 9782 XM_044326599.1 66 16 33 72 0 NA NA NA NA NA NA 9783 XM_044315530.1 109 67 43 107 126 NA NA NA NA NA NA 9784 XM_029338417.2 1195 1360 772 882 1074 Q60482 3.49e-29 DNA-directed RNA polymerase III subunit RPC9 (RNA polymerase III subunit C9) (Calcitonin gene-related peptide-receptor component protein) (CGRP-RCP) (CGRP-receptor component protein) (CGRPRCP) Cavia porcellus (Guinea pig) transcription by RNA polymerase III [GO:0006383]; transcription initiation at RNA polymerase III promoter [GO:0006384] GO:0000166; GO:0003899; GO:0005666; GO:0005886; GO:0006383; GO:0006384; GO:0009360 9785 XM_029338339.2 5162 12534 3239 7578 2676 Q95KV7 8.74e-42 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (Cell death regulatory protein GRIM-19) (Complex I-B16.6) (CI-B16.6) (Gene associated with retinoic-interferon-induced mortality 19 protein) (GRIM-19) (NADH-ubiquinone oxidoreductase B16.6 subunit) Bos taurus (Bovine) apoptotic signaling pathway [GO:0097190]; cellular response to interferon-beta [GO:0035458]; cellular response to retinoic acid [GO:0071300]; extrinsic apoptotic signaling pathway [GO:0097191]; mitochondrial respiratory chain complex I assembly [GO:0032981]; negative regulation of cell growth [GO:0030308]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of protein catabolic process [GO:0045732]; protein insertion into mitochondrial inner membrane [GO:0045039]; reactive oxygen species metabolic process [GO:0072593] GO:0005654; GO:0005737; GO:0005739; GO:0005746; GO:0005747; GO:0008137; GO:0030308; GO:0032981; GO:0035458; GO:0043280; GO:0045039; GO:0045732; GO:0045892; GO:0071300; GO:0072593; GO:0097190; GO:0097191; GO:2001243 9786 XM_044310711.1 6 0 4 17 0 NA NA NA NA NA NA 9787 XM_029336338.2 4555 2470 1235 1935 1239 NA NA NA NA NA NA 9788 XM_029346539.2 45 0 14 39 26 P32297 2.09e-92 Neuronal acetylcholine receptor subunit alpha-3 Homo sapiens (Human) acetylcholine receptor signaling pathway [GO:0095500]; activation of transmembrane receptor protein tyrosine kinase activity [GO:0007171]; behavioral response to nicotine [GO:0035095]; chemical synaptic transmission [GO:0007268]; excitatory postsynaptic potential [GO:0060079]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; locomotory behavior [GO:0007626]; membrane depolarization [GO:0051899]; nervous system development [GO:0007399]; nervous system process [GO:0050877]; regulation of acetylcholine secretion, neurotransmission [GO:0014056]; regulation of dendrite morphogenesis [GO:0048814]; regulation of membrane potential [GO:0042391]; regulation of smooth muscle contraction [GO:0006940]; response to acetylcholine [GO:1905144]; signal transduction [GO:0007165]; synaptic transmission involved in micturition [GO:0060084]; synaptic transmission, cholinergic [GO:0007271] GO:0005231; GO:0005886; GO:0005892; GO:0006811; GO:0006940; GO:0007165; GO:0007171; GO:0007268; GO:0007271; GO:0007399; GO:0007626; GO:0014056; GO:0014069; GO:0015276; GO:0015464; GO:0016020; GO:0016607; GO:0022848; GO:0030425; GO:0030594; GO:0034220; GO:0035095; GO:0042166; GO:0042391; GO:0043005; GO:0043025; GO:0044853; GO:0045202; GO:0045211; GO:0048814; GO:0050877; GO:0051899; GO:0060079; GO:0060084; GO:0095500; GO:1904315; GO:1905144 9789 XM_029323461.2 256 0 200 159 0 A2RU49 9.36e-51 Hydroxylysine kinase (5-hydroxy-L-lysine kinase) (EC 2.7.1.81) (Aminoglycoside phosphotransferase domain-containing protein 1) Homo sapiens (Human) lysine catabolic process [GO:0006554]; phosphorylation [GO:0016310] GO:0005759; GO:0006554; GO:0016310; GO:0019202; GO:0047992 9790 XR_006393846.1 0 0 5 0 25 NA NA NA NA NA NA 9791 XM_044324621.1 2198 1237 1293 2186 1826 Q8BX90 7.13e-161 Fibronectin type-III domain-containing protein 3A Mus musculus (Mouse) cell-cell adhesion [GO:0098609]; fertilization [GO:0009566]; Sertoli cell development [GO:0060009]; spermatid development [GO:0007286] GO:0000139; GO:0001669; GO:0005737; GO:0005794; GO:0005829; GO:0007286; GO:0009566; GO:0012506; GO:0016020; GO:0031410; GO:0043231; GO:0060009; GO:0098609 9792 XM_044324621.1 2198 1237 1293 2186 1826 Q8BX90 7.06e-48 Fibronectin type-III domain-containing protein 3A Mus musculus (Mouse) cell-cell adhesion [GO:0098609]; fertilization [GO:0009566]; Sertoli cell development [GO:0060009]; spermatid development [GO:0007286] GO:0000139; GO:0001669; GO:0005737; GO:0005794; GO:0005829; GO:0007286; GO:0009566; GO:0012506; GO:0016020; GO:0031410; GO:0043231; GO:0060009; GO:0098609 9793 XM_044325515.1 197 180 224 193 1234 NA NA NA NA NA NA 9794 XM_029348420.2 146 217 197 212 271 A3KG59 1.31e-121 Xaa-Arg dipeptidase (EC 3.4.13.4) Mus musculus (Mouse) proteolysis [GO:0006508]; regulation of protein metabolic process [GO:0051246] GO:0004180; GO:0005654; GO:0006508; GO:0016805; GO:0042802; GO:0051246 9795 XM_029343810.2 1255 824 981 1286 1115 Q62739 7.56e-62 Rab-3A-interacting protein (Rab3A-interacting protein) (Rabin-3) (SSX2-interacting protein) Rattus norvegicus (Rat) exocytosis [GO:0006887]; negative regulation of filopodium assembly [GO:0051490]; protein targeting to membrane [GO:0006612] GO:0005085; GO:0005634; GO:0005829; GO:0005856; GO:0006612; GO:0006887; GO:0030027; GO:0048471; GO:0051020; GO:0051490; GO:0070319; GO:1990635 9796 XM_029344543.2 0 102 0 0 0 Q5M9N0 6.41e-29 Coiled-coil domain-containing protein 158 Homo sapiens (Human) NA NA 9797 XM_044310469.1 2 0 100 0 0 NA NA NA NA NA NA 9798 XM_029351728.2 0 0 0 1 36 NA NA NA NA NA NA 9799 XM_029336052.2 8 24 7 19 5 NA NA NA NA NA NA 9800 XM_044321419.1 55 1 27 0 19 NA NA NA NA NA NA 9801 XM_044327349.1 135 62 0 43 37 NA NA NA NA NA NA 9802 XM_029333943.2 51 13 45 42 32 NA NA NA NA NA NA 9803 XM_044311220.1 7 22 30 36 56 NA NA NA NA NA NA 9804 XM_029357582.2 127 15 11 0 11 Q8BTK5 6.68e-54 SET and MYND domain-containing protein 4 (EC 2.1.1.-) Mus musculus (Mouse) heart development [GO:0007507]; methylation [GO:0032259] GO:0005634; GO:0005737; GO:0007507; GO:0008168; GO:0032259; GO:0042826; GO:0046872 9805 XM_044323341.1 84 39 230 99 106 P55011 0 Solute carrier family 12 member 2 (Basolateral Na-K-Cl symporter) (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2) Homo sapiens (Human) aging [GO:0007568]; ammonium transmembrane transport [GO:0072488]; cell volume homeostasis [GO:0006884]; cellular chloride ion homeostasis [GO:0030644]; cellular potassium ion homeostasis [GO:0030007]; cellular response to chemokine [GO:1990869]; cellular response to potassium ion [GO:0035865]; cellular sodium ion homeostasis [GO:0006883]; chloride ion homeostasis [GO:0055064]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid signaling pathway [GO:0007214]; hyperosmotic response [GO:0006972]; inorganic anion import across plasma membrane [GO:0098658]; inorganic cation import across plasma membrane [GO:0098659]; ion transport [GO:0006811]; maintenance of blood-brain barrier [GO:0035633]; negative regulation of vascular wound healing [GO:0061044]; positive regulation of aspartate secretion [GO:1904450]; positive regulation of cell volume [GO:0045795]; potassium ion homeostasis [GO:0055075]; potassium ion import across plasma membrane [GO:1990573]; regulation of matrix metallopeptidase secretion [GO:1904464]; regulation of spontaneous synaptic transmission [GO:0150003]; sodium ion homeostasis [GO:0055078]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725]; T cell chemotaxis [GO:0010818]; transepithelial ammonium transport [GO:0070634]; transepithelial chloride transport [GO:0030321]; transport across blood-brain barrier [GO:0150104] GO:0005829; GO:0005886; GO:0006811; GO:0006883; GO:0006884; GO:0006972; GO:0007214; GO:0007568; GO:0008511; GO:0008519; GO:0009925; GO:0010818; GO:0015079; GO:0015377; GO:0015379; GO:0016020; GO:0016323; GO:0016324; GO:0016328; GO:0019901; GO:0030007; GO:0030321; GO:0030644; GO:0030659; GO:0031253; GO:0035633; GO:0035725; GO:0035865; GO:0042995; GO:0043005; GO:0043025; GO:0044297; GO:0044298; GO:0045795; GO:0046873; GO:0051087; GO:0051879; GO:0055064; GO:0055075; GO:0055078; GO:0061044; GO:0070062; GO:0070634; GO:0071944; GO:0072488; GO:0098658; GO:0098659; GO:0098719; GO:0150003; GO:0150104; GO:1902476; GO:1903561; GO:1904450; GO:1904464; GO:1990573; GO:1990869 9806 XM_029355350.2 1295 4042 1985 71 697 Q9QXS1 3.17e-52 Plectin (PCN) (PLTN) (Plectin-1) (Plectin-6) Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament organization [GO:0007015]; actomyosin contractile ring assembly actin filament organization [GO:2000689]; adherens junction organization [GO:0034332]; cardiac muscle cell development [GO:0055013]; cell morphogenesis [GO:0000902]; cell motility [GO:0048870]; cellular response to extracellular stimulus [GO:0031668]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrostatic pressure [GO:0071464]; cellular response to mechanical stimulus [GO:0071260]; establishment of skin barrier [GO:0061436]; fibroblast migration [GO:0010761]; gene expression [GO:0010467]; hemidesmosome assembly [GO:0031581]; intermediate filament cytoskeleton organization [GO:0045104]; intermediate filament organization [GO:0045109]; keratinocyte development [GO:0003334]; keratinocyte differentiation [GO:0030216]; leukocyte migration involved in immune response [GO:0002522]; mitochondrion morphogenesis [GO:0070584]; mitochondrion organization [GO:0007005]; multicellular organism growth [GO:0035264]; myelination in peripheral nervous system [GO:0022011]; myoblast differentiation [GO:0045445]; negative regulation of protein kinase activity [GO:0006469]; nucleus organization [GO:0006997]; peripheral nervous system myelin maintenance [GO:0032287]; protein localization [GO:0008104]; protein-containing complex organization [GO:0043933]; regulation of ATP citrate synthase activity [GO:2000983]; regulation of vascular permeability [GO:0043114]; respiratory electron transport chain [GO:0022904]; response to food [GO:0032094]; response to nutrient [GO:0007584]; sarcomere organization [GO:0045214]; skeletal muscle fiber development [GO:0048741]; skeletal muscle tissue development [GO:0007519]; skeletal myofibril assembly [GO:0014866]; skin development [GO:0043588]; T cell chemotaxis [GO:0010818]; tight junction organization [GO:0120193]; transmission of nerve impulse [GO:0019226]; wound healing [GO:0042060] GO:0000902; GO:0002162; GO:0002522; GO:0003334; GO:0003779; GO:0005198; GO:0005200; GO:0005737; GO:0005741; GO:0005829; GO:0005903; GO:0005925; GO:0006469; GO:0006997; GO:0007005; GO:0007015; GO:0007519; GO:0007584; GO:0008092; GO:0008104; GO:0008307; GO:0009925; GO:0010467; GO:0010761; GO:0010818; GO:0014866; GO:0016020; GO:0016324; GO:0016528; GO:0019226; GO:0022011; GO:0022904; GO:0030016; GO:0030018; GO:0030036; GO:0030056; GO:0030216; GO:0030424; GO:0030425; GO:0030506; GO:0031532; GO:0031581; GO:0031668; GO:0032094; GO:0032287; GO:0034332; GO:0035264; GO:0042060; GO:0042383; GO:0043114; GO:0043209; GO:0043292; GO:0043588; GO:0043621; GO:0043933; GO:0045104; GO:0045109; GO:0045111; GO:0045214; GO:0045445; GO:0047485; GO:0048471; GO:0048741; GO:0048870; GO:0051015; GO:0055013; GO:0061436; GO:0070584; GO:0071260; GO:0071464; GO:0071498; GO:0071944; GO:0120193; GO:2000689; GO:2000983 9807 XM_044320909.1 0 289 0 0 161 NA NA NA NA NA NA 9808 XM_044320088.1 100 44 59 271 94 NA NA NA NA NA NA 9809 XM_044319995.1 0 0 22 0 0 NA NA NA NA NA NA 9810 XM_029328445.2 373 192 126 298 253 Q5SVL6 8.16e-65 Rap1 GTPase-activating protein 2 (Rap1GAP2) (GTPase-activating Rap/Ran-GAP domain-like protein 4) Mus musculus (Mouse) activation of GTPase activity [GO:0090630]; negative regulation of neuron projection development [GO:0010977]; regulation of cell size [GO:0008361]; regulation of small GTPase mediated signal transduction [GO:0051056] GO:0005096; GO:0005737; GO:0005813; GO:0005829; GO:0005886; GO:0008361; GO:0010977; GO:0031965; GO:0043005; GO:0051056; GO:0090630 9811 XM_044321589.1 20 0 9 0 0 NA NA NA NA NA NA 9812 XR_006394158.1 6 0 0 3 16 NA NA NA NA NA NA 9813 XR_006395567.1 25 7 0 4 0 NA NA NA NA NA NA 9814 XM_044327497.1 130 58 91 89 87 Q9R1A8 0 E3 ubiquitin-protein ligase COP1 (EC 2.3.2.27) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1) (RING finger and WD repeat domain protein 2) (RING-type E3 ubiquitin transferase RFWD2) Mus musculus (Mouse) positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; response to ionizing radiation [GO:0010212] GO:0000139; GO:0010212; GO:0016607; GO:0031464; GO:0032436; GO:0043161; GO:0046872; GO:0061630 9815 XM_044316120.1 27 21 24 71 46 NA NA NA NA NA NA 9816 XM_029332991.2 55 57 30 94 129 NA NA NA NA NA NA 9817 XM_044316185.1 22 0 0 0 0 NA NA NA NA NA NA 9818 XR_006391930.1 354 285 339 797 411 NA NA NA NA NA NA 9819 XM_044320086.1 91 47 117 396 106 NA NA NA NA NA NA 9820 XM_029355164.2 9 0 0 16 9 NA NA NA NA NA NA 9821 XR_006395435.1 273 210 114 210 192 Q0EEE2 1.11e-31 Patched domain-containing protein 3 (RND-type protein RNDEu-3) Mus musculus (Mouse) NA GO:0005783; GO:0005789; GO:0005886; GO:0016020; GO:0097225 9822 XM_029342127.2 1778 2317 1750 1574 990 Q923G2 5.88e-85 DNA-directed RNA polymerases I, II, and III subunit RPABC3 (RNA polymerases I, II, and III subunit ABC3) (DNA-directed RNA polymerase II subunit H) (RPB17) (RPB8 homolog) Mus musculus (Mouse) transcription by RNA polymerase II [GO:0006366] GO:0003697; GO:0005634; GO:0005654; GO:0005665; GO:0005666; GO:0005736; GO:0006366; GO:0032993 9823 XM_029340613.2 86 0 56 76 311 NA NA NA NA NA NA 9824 XM_044319044.1 136 39 53 0 0 NA NA NA NA NA NA 9825 XM_044326661.1 5 9 33 34 52 P79385 1.42e-26 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (SED1) (Sperm surface protein SP47) (PP47) Sus scrofa (Pig) angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; single fertilization [GO:0007338] GO:0001525; GO:0002080; GO:0005576; GO:0007155; GO:0007338 9826 XM_029337002.2 7998 17290 10581 11174 6302 O95685 5.45e-26 Protein phosphatase 1 regulatory subunit 3D (Protein phosphatase 1 regulatory subunit 6) (PP1 subunit R6) (Protein phosphatase 1-binding subunit R6) Homo sapiens (Human) glycogen metabolic process [GO:0005977]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of glycogen catabolic process [GO:0005981] GO:0000164; GO:0004722; GO:0005977; GO:0005979; GO:0005981; GO:0008157; GO:0042587; GO:0043231; GO:2001069 9827 XM_029338059.2 0 0 144 0 0 Q8BUG5 1.61e-96 Calcyphosin-2 (Calcyphosine-2) Mus musculus (Mouse) NA GO:0005509 9828 XM_029327552.2 1150 1126 526 1119 997 NA NA NA NA NA NA 9829 XM_029335313.2 279 579 292 150 265 NA NA NA NA NA NA 9830 XM_044319625.1 2 0 10 4 7 NA NA NA NA NA NA 9831 XM_029329297.2 383 586 346 580 722 NA NA NA NA NA NA 9832 XR_003828298.2 1 1 0 8 0 NA NA NA NA NA NA 9833 XM_029335154.2 429 680 661 965 1161 NA NA NA NA NA NA 9834 XM_044309285.1 0 0 0 0 7 NA NA NA NA NA NA 9835 XM_044323133.1 1074 615 648 124 963 O70511 1.44e-75 Ankyrin-3 (ANK-3) (Ankyrin-G) Rattus norvegicus (Rat) anterograde axonal transport [GO:0008089]; axon development [GO:0061564]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; clustering of voltage-gated sodium channels [GO:0045162]; establishment of protein localization [GO:0045184]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in cell [GO:0032507]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of endocytosis [GO:0045806]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; regulation of protein targeting [GO:1903533]; response to immobilization stress [GO:0035902]; signal transduction [GO:0007165]; synapse organization [GO:0050808] GO:0000281; GO:0005200; GO:0005737; GO:0005764; GO:0005856; GO:0005886; GO:0007009; GO:0007165; GO:0007409; GO:0007411; GO:0007528; GO:0008089; GO:0008092; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014704; GO:0014731; GO:0016020; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030424; GO:0030425; GO:0030507; GO:0030674; GO:0030951; GO:0031594; GO:0032507; GO:0033268; GO:0033270; GO:0034112; GO:0035902; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045162; GO:0045184; GO:0045202; GO:0045211; GO:0045296; GO:0045806; GO:0045838; GO:0050808; GO:0061564; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:0140031; GO:1900827; GO:1901224; GO:1902260; GO:1903533; GO:1904115; GO:2000651; GO:2001259 9836 XM_044323133.1 1074 615 648 124 963 O70511 2.34e-51 Ankyrin-3 (ANK-3) (Ankyrin-G) Rattus norvegicus (Rat) anterograde axonal transport [GO:0008089]; axon development [GO:0061564]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; clustering of voltage-gated sodium channels [GO:0045162]; establishment of protein localization [GO:0045184]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in cell [GO:0032507]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of endocytosis [GO:0045806]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; regulation of protein targeting [GO:1903533]; response to immobilization stress [GO:0035902]; signal transduction [GO:0007165]; synapse organization [GO:0050808] GO:0000281; GO:0005200; GO:0005737; GO:0005764; GO:0005856; GO:0005886; GO:0007009; GO:0007165; GO:0007409; GO:0007411; GO:0007528; GO:0008089; GO:0008092; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014704; GO:0014731; GO:0016020; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030424; GO:0030425; GO:0030507; GO:0030674; GO:0030951; GO:0031594; GO:0032507; GO:0033268; GO:0033270; GO:0034112; GO:0035902; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045162; GO:0045184; GO:0045202; GO:0045211; GO:0045296; GO:0045806; GO:0045838; GO:0050808; GO:0061564; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:0140031; GO:1900827; GO:1901224; GO:1902260; GO:1903533; GO:1904115; GO:2000651; GO:2001259 9837 XM_044323133.1 1074 615 648 124 963 O70511 1.28e-27 Ankyrin-3 (ANK-3) (Ankyrin-G) Rattus norvegicus (Rat) anterograde axonal transport [GO:0008089]; axon development [GO:0061564]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; clustering of voltage-gated sodium channels [GO:0045162]; establishment of protein localization [GO:0045184]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in cell [GO:0032507]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of endocytosis [GO:0045806]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; regulation of protein targeting [GO:1903533]; response to immobilization stress [GO:0035902]; signal transduction [GO:0007165]; synapse organization [GO:0050808] GO:0000281; GO:0005200; GO:0005737; GO:0005764; GO:0005856; GO:0005886; GO:0007009; GO:0007165; GO:0007409; GO:0007411; GO:0007528; GO:0008089; GO:0008092; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014704; GO:0014731; GO:0016020; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030424; GO:0030425; GO:0030507; GO:0030674; GO:0030951; GO:0031594; GO:0032507; GO:0033268; GO:0033270; GO:0034112; GO:0035902; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045162; GO:0045184; GO:0045202; GO:0045211; GO:0045296; GO:0045806; GO:0045838; GO:0050808; GO:0061564; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:0140031; GO:1900827; GO:1901224; GO:1902260; GO:1903533; GO:1904115; GO:2000651; GO:2001259 9838 XM_044323133.1 1074 615 648 124 963 O70511 3.79e-26 Ankyrin-3 (ANK-3) (Ankyrin-G) Rattus norvegicus (Rat) anterograde axonal transport [GO:0008089]; axon development [GO:0061564]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; clustering of voltage-gated sodium channels [GO:0045162]; establishment of protein localization [GO:0045184]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in cell [GO:0032507]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of endocytosis [GO:0045806]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; regulation of protein targeting [GO:1903533]; response to immobilization stress [GO:0035902]; signal transduction [GO:0007165]; synapse organization [GO:0050808] GO:0000281; GO:0005200; GO:0005737; GO:0005764; GO:0005856; GO:0005886; GO:0007009; GO:0007165; GO:0007409; GO:0007411; GO:0007528; GO:0008089; GO:0008092; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014704; GO:0014731; GO:0016020; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030424; GO:0030425; GO:0030507; GO:0030674; GO:0030951; GO:0031594; GO:0032507; GO:0033268; GO:0033270; GO:0034112; GO:0035902; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045162; GO:0045184; GO:0045202; GO:0045211; GO:0045296; GO:0045806; GO:0045838; GO:0050808; GO:0061564; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:0140031; GO:1900827; GO:1901224; GO:1902260; GO:1903533; GO:1904115; GO:2000651; GO:2001259 9839 XM_029339908.2 29 23 0 0 4 Q6NN55 4e-93 Lysophospholipid acyltransferase 6 (LPLAT 6) (EC 2.3.1.-) (EC 2.3.1.23) (EC 2.3.1.n6) (EC 2.3.1.n7) (Membrane-bound acyltransferase 6) (MBOA 6) (Oysgedart) (Oys) Drosophila melanogaster (Fruit fly) germ cell migration [GO:0008354]; lipid modification [GO:0030258]; phospholipid metabolic process [GO:0006644]; plasma membrane organization [GO:0007009]; sperm individualization [GO:0007291] GO:0005783; GO:0006644; GO:0007009; GO:0007291; GO:0008354; GO:0016020; GO:0016746; GO:0030258; GO:0071617 9840 XM_029347921.2 183 58 169 110 256 NA NA NA NA NA NA 9841 XM_029329982.2 481 126 303 402 660 P0C218 2.77e-177 Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.15) (EC 3.6.4.13) (DEAD box protein 20) Danio rerio (Zebrafish) (Brachydanio rerio) spliceosomal snRNP assembly [GO:0000387] GO:0000387; GO:0003677; GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005829; GO:0016887; GO:0032797; GO:0034719 9842 XR_006397164.1 0 11 5 0 2 NA NA NA NA NA NA 9843 XR_006392008.1 45 63 122 23 9 NA NA NA NA NA NA 9844 XM_029350750.2 542 627 494 323 987 P92208 0 Stress-activated protein kinase JNK (dJNK) (EC 2.7.11.24) (Protein basket) Drosophila melanogaster (Fruit fly) antibacterial humoral response [GO:0019731]; axon extension [GO:0048675]; axon guidance [GO:0007411]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; chorion micropyle formation [GO:0046844]; collateral sprouting of injured axon [GO:0048674]; determination of digestive tract left/right asymmetry [GO:0071907]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal closure, spreading of leading edge cells [GO:0007395]; embryonic anterior midgut (ectodermal) morphogenesis [GO:0048615]; engulfment of apoptotic cell [GO:0043652]; follicle cell of egg chamber development [GO:0030707]; imaginal disc fusion, thorax closure [GO:0046529]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; JUN phosphorylation [GO:0007258]; long-term memory [GO:0007616]; melanization defense response [GO:0035006]; mushroom body development [GO:0016319]; neuron development [GO:0048666]; neuron projection morphogenesis [GO:0048812]; peptidoglycan recognition protein signaling pathway [GO:0061057]; positive regulation of autophagy [GO:0010508]; positive regulation of border follicle cell migration [GO:1903688]; positive regulation of cell death [GO:0010942]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron remodeling [GO:1904801]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; wound healing [GO:0042060]; wound healing, spreading of epidermal cells [GO:0035313] GO:0004672; GO:0004674; GO:0004705; GO:0004707; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006979; GO:0007254; GO:0007258; GO:0007391; GO:0007395; GO:0007411; GO:0007616; GO:0009408; GO:0010508; GO:0010628; GO:0010942; GO:0016319; GO:0019731; GO:0030424; GO:0030425; GO:0030707; GO:0033209; GO:0034599; GO:0034614; GO:0035006; GO:0035313; GO:0035556; GO:0042060; GO:0043652; GO:0046529; GO:0046843; GO:0046844; GO:0048010; GO:0048615; GO:0048666; GO:0048674; GO:0048675; GO:0048803; GO:0048812; GO:0061057; GO:0071243; GO:0071276; GO:0071907; GO:0106310; GO:1903688; GO:1904801 9845 XR_006394193.1 14 22 2 20 27 NA NA NA NA NA NA 9846 XM_029340914.2 0 0 60 0 0 B2RPY5 3.6e-21 G-protein coupled receptor 161 Mus musculus (Mouse) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:1901621] GO:0004930; GO:0005929; GO:0007186; GO:0007189; GO:0043005; GO:0055037; GO:0060170; GO:0097386; GO:1901621 9847 XM_029335556.2 710 1069 481 1052 653 A6QP70 5.82e-33 Beta-sarcoglycan (Beta-SG) Bos taurus (Bovine) muscle organ development [GO:0007517] GO:0005737; GO:0005856; GO:0007517; GO:0016012; GO:0042383 9848 XM_044318129.1 60 26 9 22 21 NA NA NA NA NA NA 9849 XR_006395161.1 44 36 10 91 88 Q4R1I4 5.57e-23 Melanopsin (Opsin-4) (amphi-MOP) Branchiostoma belcheri (Amphioxus) G protein-coupled receptor signaling pathway [GO:0007186]; phototransduction [GO:0007602]; visual perception [GO:0007601] GO:0005886; GO:0007186; GO:0007601; GO:0007602; GO:0008020; GO:0016020 9850 XR_006395161.1 44 36 10 91 88 Q4R1I4 5.57e-23 Melanopsin (Opsin-4) (amphi-MOP) Branchiostoma belcheri (Amphioxus) G protein-coupled receptor signaling pathway [GO:0007186]; phototransduction [GO:0007602]; visual perception [GO:0007601] GO:0005886; GO:0007186; GO:0007601; GO:0007602; GO:0008020; GO:0016020 9851 XR_006395161.1 44 36 10 91 88 Q4R1I4 5.57e-23 Melanopsin (Opsin-4) (amphi-MOP) Branchiostoma belcheri (Amphioxus) G protein-coupled receptor signaling pathway [GO:0007186]; phototransduction [GO:0007602]; visual perception [GO:0007601] GO:0005886; GO:0007186; GO:0007601; GO:0007602; GO:0008020; GO:0016020 9852 XR_006391815.1 15 0 16 0 74 NA NA NA NA NA NA 9853 XM_029345688.2 15 12 5 10 8 NA NA NA NA NA NA 9854 XM_029355865.2 7 8 8 6 43 P13608 9.75e-23 Aggrecan core protein (Cartilage-specific proteoglycan core protein) (CSPCP) Bos taurus (Bovine) cell adhesion [GO:0007155]; central nervous system development [GO:0007417]; skeletal system development [GO:0001501] GO:0001501; GO:0005509; GO:0005540; GO:0005576; GO:0007155; GO:0007417; GO:0030246; GO:0031012 9855 XM_044317614.1 25529 15077 11521 47294 43808 B8V7R6 0 Collagen alpha chain Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005201; GO:0005576; GO:0005581 9856 XM_029342419.2 349 181 0 308 0 P16157 2.48e-94 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 9857 XM_029342419.2 349 181 0 308 0 P16157 1.48e-86 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 9858 XM_029342419.2 349 181 0 308 0 P16157 4.16e-86 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 9859 XM_029342419.2 349 181 0 308 0 P16157 2.43e-65 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 9860 XR_006395702.1 53 5 80 19 194 NA NA NA NA NA NA 9861 XM_029344010.2 136 19 16 84 0 A1L1W9 3.27e-70 Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10) Danio rerio (Zebrafish) (Brachydanio rerio) aromatic amino acid transport [GO:0015801]; thyroid hormone transport [GO:0070327] GO:0005302; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0070327 9862 XM_029348334.2 263 317 177 217 465 NA NA NA NA NA NA 9863 XM_029349142.2 390 169 310 539 528 NA NA NA NA NA NA 9864 XR_003824047.2 117 57 27 28 58 NA NA NA NA NA NA 9865 XM_029347148.2 0 10 0 0 0 A0JPE1 2.98e-28 Divergent protein kinase domain 1B (Protein FAM69B) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005789 9866 XM_044318702.1 26 14 25 61 76 P0CI65 8.45e-47 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 9867 XM_044318702.1 26 14 25 61 76 P0CI65 7.22e-46 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 9868 XM_044318702.1 26 14 25 61 76 P0CI65 3.41e-38 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 9869 XM_029349339.2 216 78 195 244 181 NA NA NA NA NA NA 9870 XM_044318837.1 0 0 0 0 258 Q91Z40 2.8e-46 Guanylate-binding protein 7 (EC 3.6.5.-) (GTP-binding protein 7) (GBP-7) (Guanine nucleotide-binding protein 7) (Guanylate-binding protein 4-like) Mus musculus (Mouse) adhesion of symbiont to host [GO:0044406]; cellular response to interferon-beta [GO:0035458]; cellular response to type II interferon [GO:0071346]; defense response to Gram-positive bacterium [GO:0050830]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; negative regulation of cytokine production [GO:0001818]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of type I interferon production [GO:0032480]; negative regulation of type III interferon production [GO:0034345]; positive regulation of viral genome replication [GO:0045070]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122] GO:0001818; GO:0003924; GO:0005525; GO:0016020; GO:0020005; GO:0031410; GO:0032480; GO:0034345; GO:0035458; GO:0042832; GO:0043122; GO:0044406; GO:0045070; GO:0046426; GO:0050830; GO:0051607; GO:0071346 9871 XR_006394274.1 0 26 0 0 0 NA NA NA NA NA NA 9872 XM_029338290.2 698 543 324 1049 804 Q9DBN1 1.6e-50 Stimulated by retinoic acid gene 6 protein-like (STRA6-like protein) (Retinol-binding protein 4 receptor 2) (RBP4 receptor 2) Mus musculus (Mouse) establishment of localization in cell [GO:0051649]; retinol transport [GO:0034633]; vitamin A import into cell [GO:0071939] GO:0005886; GO:0034633; GO:0051649; GO:0071939 9873 XM_044319157.1 92 51 28 106 75 P0DX22 1.53e-55 NA NA NA NA 9874 XM_044310247.1 104 208 162 239 339 Q5F371 3.04e-31 Protein strawberry notch homolog 1 Gallus gallus (Chicken) regulation of DNA-templated transcription [GO:0006355]; regulation of response to stimulus [GO:0048583] GO:0005634; GO:0006355; GO:0031490; GO:0042393; GO:0048583 9875 XM_029349166.2 568 301 131 90 192 Q9CPV7 1.73e-98 Palmitoyltransferase ZDHHC6 (EC 2.3.1.225) (Stearoyltransferase ZDHHC6) (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 6) (DHHC-6) Mus musculus (Mouse) peptidyl-L-cysteine S-palmitoylation [GO:0018230]; positive regulation of mitochondrial fusion [GO:0010636]; protein palmitoylation [GO:0018345]; protein stearoylation [GO:0140438]; protein targeting to membrane [GO:0006612] GO:0005783; GO:0005789; GO:0005794; GO:0006612; GO:0010636; GO:0016409; GO:0018230; GO:0018345; GO:0019706; GO:0140438; GO:0140439 9876 XM_044318443.1 1559 1212 1089 1591 1601 A3KN83 1.01e-63 Protein strawberry notch homolog 1 (Monocyte protein 3) (MOP-3) Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355]; regulation of response to stimulus [GO:0048583] GO:0005634; GO:0006355; GO:0031490; GO:0042393; GO:0048583 9877 XM_044317913.1 87 88 52 61 63 Q09081 8.35e-65 Potassium voltage-gated channel subfamily A member 2 (KC22) (Voltage-gated potassium channel subunit Kv1.2) Oryctolagus cuniculus (Rabbit) neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233] GO:0005249; GO:0005251; GO:0005789; GO:0005886; GO:0008076; GO:0014059; GO:0019228; GO:0019233; GO:0021633; GO:0030027; GO:0030424; GO:0030425; GO:0031258; GO:0032809; GO:0033010; GO:0034765; GO:0042734; GO:0043194; GO:0043204; GO:0043679; GO:0044224; GO:0045188; GO:0051260; GO:0071805 9878 XM_044321170.1 0 0 4 10 53 NA NA NA NA NA NA 9879 XM_044314462.1 982 353 542 778 2282 NA NA NA NA NA NA 9880 XM_029327506.2 16 3 9 0 0 NA NA NA NA NA NA 9881 XM_029332979.2 109 60 0 176 64 Q9H0B8 3.73e-31 Cysteine-rich secretory protein LCCL domain-containing 2 (Cysteine-rich secretory protein 11) (CRISP-11) (LCCL domain-containing cysteine-rich secretory protein 2) Homo sapiens (Human) extracellular matrix organization [GO:0030198]; face morphogenesis [GO:0060325]; lung development [GO:0030324] GO:0005539; GO:0005576; GO:0005615; GO:0008201; GO:0030133; GO:0030198; GO:0030324; GO:0031012; GO:0034774; GO:0060325; GO:0070062; GO:1904813 9882 XR_006396548.1 2911 3837 2290 2589 1299 Q2KHS5 3.3e-95 2-acylglycerol O-acyltransferase 2-A (EC 2.3.1.22) (Acyl-CoA:monoacylglycerol acyltransferase 2-A) (MGAT2-A) (Monoacylglycerol O-acyltransferase 2-A) Xenopus laevis (African clawed frog) glycerol metabolic process [GO:0006071]; monoacylglycerol biosynthetic process [GO:0006640]; triglyceride biosynthetic process [GO:0019432] GO:0003846; GO:0005789; GO:0006071; GO:0006640; GO:0019432; GO:1990578 9883 XM_044325371.1 6 1 37 2 29 NA NA NA NA NA NA 9884 XM_044313816.1 9 4 0 1 0 NA NA NA NA NA NA 9885 XM_029340458.2 355 217 222 301 541 NA NA NA NA NA NA 9886 XM_029355720.2 1 4 6 4 4 Q09575 2.34e-27 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 9887 XM_029345034.2 625 404 453 639 614 NA NA NA NA NA NA 9888 XM_044307417.1 17 0 20 86 84 NA NA NA NA NA NA 9889 XM_029347137.2 78 1932 51 122 90 NA NA NA NA NA NA 9890 XM_029327287.2 91 39 78 117 424 O42406 1.7e-112 Homeobox protein SIX3 (CSIX3) (Sine oculis homeobox homolog 3) Gallus gallus (Chicken) apoptotic process involved in development [GO:1902742]; brain development [GO:0007420]; cell proliferation in forebrain [GO:0021846]; epithelial cell maturation [GO:0002070]; eye development [GO:0001654]; forebrain dorsal/ventral pattern formation [GO:0021798]; lens development in camera-type eye [GO:0002088]; lens fiber cell apoptotic process [GO:1990086]; lens fiber cell differentiation [GO:0070306]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of Wnt signaling pathway [GO:0030178]; neuroblast differentiation [GO:0014016]; neuroblast migration [GO:0097402]; optic vesicle morphogenesis [GO:0003404]; pituitary gland development [GO:0021983]; proximal/distal axis specification [GO:0009946]; regulation of cell cycle phase transition [GO:1901987]; regulation of cell population proliferation [GO:0042127]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neural retina development [GO:0061074]; regulation of neuroblast proliferation [GO:1902692]; regulation of transcription by RNA polymerase II [GO:0006357]; telencephalon development [GO:0021537]; telencephalon regionalization [GO:0021978] GO:0000978; GO:0000981; GO:0001228; GO:0001654; GO:0002070; GO:0002088; GO:0003404; GO:0003677; GO:0005634; GO:0005667; GO:0006357; GO:0007420; GO:0009946; GO:0014016; GO:0021537; GO:0021798; GO:0021846; GO:0021978; GO:0021983; GO:0030178; GO:0042127; GO:0045665; GO:0045892; GO:0061074; GO:0070306; GO:0097402; GO:1901987; GO:1902692; GO:1902742; GO:1990086; GO:2000177 9891 XR_006396732.1 110 21 23 20 47 NA NA NA NA NA NA 9892 XM_029330344.2 1216 1462 1574 1408 2246 Q924A2 1.68e-40 Protein capicua homolog Mus musculus (Mouse) brain development [GO:0007420]; learning [GO:0007612]; lung alveolus development [GO:0048286]; memory [GO:0007613]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357]; social behavior [GO:0035176]; transcription by RNA polymerase II [GO:0006366] GO:0000122; GO:0000977; GO:0000981; GO:0003682; GO:0005634; GO:0005654; GO:0006357; GO:0006366; GO:0007420; GO:0007612; GO:0007613; GO:0032991; GO:0035176; GO:0043231; GO:0045892; GO:0048286 9893 XM_029330344.2 1216 1462 1574 1408 2246 Q924A2 2.1e-21 Protein capicua homolog Mus musculus (Mouse) brain development [GO:0007420]; learning [GO:0007612]; lung alveolus development [GO:0048286]; memory [GO:0007613]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357]; social behavior [GO:0035176]; transcription by RNA polymerase II [GO:0006366] GO:0000122; GO:0000977; GO:0000981; GO:0003682; GO:0005634; GO:0005654; GO:0006357; GO:0006366; GO:0007420; GO:0007612; GO:0007613; GO:0032991; GO:0035176; GO:0043231; GO:0045892; GO:0048286 9894 XM_044316502.1 181 31 31 269 49 NA NA NA NA NA NA 9895 XM_044329075.1 6 0 10 3 0 NA NA NA NA NA NA 9896 XM_029331854.2 1954 1876 1214 2583 1042 O08653 2.26e-39 Telomerase protein component 1 (rTLP1) (Telomerase-associated protein 1) (Telomerase protein 1) (p230) (p240) (p80 telomerase homolog) Rattus norvegicus (Rat) RNA-templated DNA biosynthetic process [GO:0006278]; telomere maintenance via recombination [GO:0000722] GO:0000722; GO:0000781; GO:0002039; GO:0003723; GO:0005524; GO:0005697; GO:0005737; GO:0006278; GO:0016363; GO:0019899; GO:0070034; GO:1990904 9897 XM_044307745.1 1461 2207 567 1063 896 NA NA NA NA NA NA 9898 XM_044309229.1 155 80 174 168 238 NA NA NA NA NA NA 9899 XM_029339964.2 1496 1435 1743 1876 1588 P09041 0 Phosphoglycerate kinase 2 (EC 2.7.2.3) (Phosphoglycerate kinase, testis specific) Mus musculus (Mouse) flagellated sperm motility [GO:0030317]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; phosphorylation [GO:0016310] GO:0004618; GO:0005524; GO:0005829; GO:0005929; GO:0006094; GO:0006096; GO:0016310; GO:0030317; GO:0035686; GO:0043531 9900 XM_029338387.2 195 158 78 261 238 Q9EQ15 7.01e-82 Guanine nucleotide-binding protein subunit beta-like protein 1 (G protein subunit beta-like protein 1) (WD repeat-containing protein 14) (WD40 repeat-containing protein deleted in VCFS) (WDVCF) Mus musculus (Mouse) social behavior [GO:0035176] GO:0005737; GO:0035176 9901 XM_044325962.1 14 46 73 46 63 NA NA NA NA NA NA 9902 XM_029325494.2 151 42 28 144 124 NA NA NA NA NA NA 9903 XR_006394767.1 1034 576 288 431 374 NA NA NA NA NA NA 9904 XM_044311172.1 0 53 74 0 0 NA NA NA NA NA NA 9905 XM_029333485.2 1198 1093 830 1083 557 A7SAZ1 4.99e-46 UPF0669 protein v1g209471 Nematostella vectensis (Starlet sea anemone) NA GO:0005576 9906 XM_044309016.1 0 9 67 100 177 Q3UQ28 4.12e-30 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 9907 XM_044309016.1 0 9 67 100 177 Q3UQ28 7.95e-24 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 9908 XM_029323487.2 1328 816 433 1034 1180 P13686 2.23e-92 Tartrate-resistant acid phosphatase type 5 (TR-AP) (EC 3.1.3.2) (Tartrate-resistant acid ATPase) (TrATPase) (Type 5 acid phosphatase) Homo sapiens (Human) bone morphogenesis [GO:0060349]; bone resorption [GO:0045453]; defense response to Gram-positive bacterium [GO:0050830]; dephosphorylation [GO:0016311]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of superoxide anion generation [GO:0032929]; negative regulation of tumor necrosis factor production [GO:0032720]; nitric oxide biosynthetic process [GO:0006809]; response to cytokine [GO:0034097]; response to lipopolysaccharide [GO:0032496]; superoxide anion generation [GO:0042554] GO:0003993; GO:0005764; GO:0005829; GO:0006809; GO:0008198; GO:0008199; GO:0010936; GO:0016020; GO:0016311; GO:0032496; GO:0032691; GO:0032695; GO:0032720; GO:0032929; GO:0034097; GO:0042554; GO:0045019; GO:0045453; GO:0050728; GO:0050830; GO:0060349 9909 XM_044308566.1 54 39 74 77 127 NA NA NA NA NA NA 9910 XM_029341829.2 387 179 186 211 409 NA NA NA NA NA NA 9911 XM_044309169.1 263 363 140 589 498 NA NA NA NA NA NA 9912 XM_044319179.1 0 0 0 0 32 NA NA NA NA NA NA 9913 XR_006393232.1 138 144 141 197 284 NA NA NA NA NA NA 9914 XM_029347566.2 125 146 212 177 178 NA NA NA NA NA NA 9915 XM_044306863.1 20 0 5 4 106 B3EWY9 0 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 9916 XR_006396651.1 0 4 0 0 10 NA NA NA NA NA NA 9917 XM_029328347.2 42 7 28 28 44 NA NA NA NA NA NA 9918 XM_044328851.1 6 3 25 43 9 NA NA NA NA NA NA 9919 XM_044322939.1 16 0 20 0 16 NA NA NA NA NA NA 9920 XM_029337586.2 1070 779 501 756 775 A8WGF7 5.32e-151 Protein spinster homolog 1 (Spns1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) lipid transport [GO:0006869] GO:0005743; GO:0006869; GO:0022857 9921 XM_044317997.1 39 67 27 29 45 NA NA NA NA NA NA 9922 XM_029358021.2 1 3 0 15 19 P29029 3.51e-46 Endochitinase (EC 3.2.1.14) (Soluble cell wall protein 2) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) cell wall organization [GO:0071555]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]; septum digestion after cytokinesis [GO:0000920] GO:0000272; GO:0000324; GO:0000920; GO:0004568; GO:0005576; GO:0005635; GO:0005783; GO:0005935; GO:0006032; GO:0008061; GO:0008843; GO:0009277; GO:0071555 9923 XM_044320657.1 8 0 0 2 13 NA NA NA NA NA NA 9924 XM_044313779.1 822 994 686 918 814 Q05158 3.37e-27 Cysteine and glycine-rich protein 2 (Cysteine-rich protein 2) (CRP2) Coturnix japonica (Japanese quail) (Coturnix coturnix japonica) cell differentiation [GO:0030154] GO:0005634; GO:0008270; GO:0030154 9925 XM_029334619.2 304 242 195 254 342 Q148G4 1.95e-128 Deoxyribonuclease TATDN1 (EC 3.1.21.-) Bos taurus (Bovine) NA GO:0005654; GO:0008296; GO:0046872 9926 XM_029349906.1 415 345 240 394 472 Q8K4Y7 2.33e-126 Soluble calcium-activated nucleotidase 1 (SCAN-1) (EC 3.6.1.6) (Apyrase homolog) Rattus norvegicus (Rat) proteoglycan biosynthetic process [GO:0030166] GO:0004382; GO:0005509; GO:0005789; GO:0016020; GO:0030166; GO:0032580; GO:0042803; GO:0043262; GO:0045134 9927 XM_044324888.1 194 123 118 156 156 NA NA NA NA NA NA 9928 XM_029354528.2 148 65 60 72 105 NA NA NA NA NA NA 9929 XM_044322347.1 0 0 15 0 6 NA NA NA NA NA NA 9930 XM_044320206.1 37 71 38 5 0 NA NA NA NA NA NA 9931 XM_029352114.2 1292 913 967 990 920 Q5E9J9 1.35e-78 STE20-related kinase adapter protein alpha (STRAD alpha) (STE20-related adapter protein) Bos taurus (Bovine) activation of protein kinase activity [GO:0032147]; cell cycle [GO:0007049]; protein export from nucleus [GO:0006611]; protein phosphorylation [GO:0006468] GO:0004672; GO:0005524; GO:0005634; GO:0005737; GO:0006468; GO:0006611; GO:0007049; GO:0030295; GO:0032147; GO:0043539; GO:1902554 9932 XM_044315560.1 1784 1258 1220 2258 1907 Q4G0P3 0 Hydrocephalus-inducing protein homolog Homo sapiens (Human) axonemal central apparatus assembly [GO:1904158]; cilium movement [GO:0003341]; epithelial cell development [GO:0002064]; trachea development [GO:0060438]; ventricular system development [GO:0021591] GO:0002064; GO:0003341; GO:0005930; GO:0021591; GO:0060438; GO:1904158; GO:1990716; GO:1990718 9933 XM_044315560.1 1784 1258 1220 2258 1907 Q4G0P3 0 Hydrocephalus-inducing protein homolog Homo sapiens (Human) axonemal central apparatus assembly [GO:1904158]; cilium movement [GO:0003341]; epithelial cell development [GO:0002064]; trachea development [GO:0060438]; ventricular system development [GO:0021591] GO:0002064; GO:0003341; GO:0005930; GO:0021591; GO:0060438; GO:1904158; GO:1990716; GO:1990718 9934 XM_044315560.1 1784 1258 1220 2258 1907 Q4G0P3 7.6e-147 Hydrocephalus-inducing protein homolog Homo sapiens (Human) axonemal central apparatus assembly [GO:1904158]; cilium movement [GO:0003341]; epithelial cell development [GO:0002064]; trachea development [GO:0060438]; ventricular system development [GO:0021591] GO:0002064; GO:0003341; GO:0005930; GO:0021591; GO:0060438; GO:1904158; GO:1990716; GO:1990718 9935 XR_003827266.2 51 51 1123 1885 460 NA NA NA NA NA NA 9936 XM_029344190.2 100 202 87 419 606 NA NA NA NA NA NA 9937 XM_029341143.2 0 0 0 0 269 NA NA NA NA NA NA 9938 XM_044307759.1 60 80 54 101 112 NA NA NA NA NA NA 9939 XM_029357024.2 1651 2746 1416 3023 3534 Q64640 2.19e-142 Adenosine kinase (AK) (EC 2.7.1.20) (Adenosine 5'-phosphotransferase) Rattus norvegicus (Rat) adenosine metabolic process [GO:0046085]; AMP biosynthetic process [GO:0006167]; AMP salvage [GO:0044209]; circadian regulation of gene expression [GO:0032922]; dAMP salvage [GO:0106383]; dATP biosynthetic process [GO:0006175]; GMP salvage [GO:0032263]; phosphorylation [GO:0016310]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of T cell proliferation [GO:0042102]; purine nucleobase metabolic process [GO:0006144]; purine ribonucleoside salvage [GO:0006166]; type B pancreatic cell proliferation [GO:0044342] GO:0004001; GO:0004136; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006144; GO:0006166; GO:0006167; GO:0006175; GO:0010613; GO:0016310; GO:0032263; GO:0032922; GO:0042102; GO:0044209; GO:0044342; GO:0046085; GO:0046872; GO:0106383 9940 XM_044312720.1 7 0 1 43 1 NA NA NA NA NA NA 9941 XM_044311598.1 179 0 0 33 84 NA NA NA NA NA NA 9942 XM_044323883.1 55 16 53 49 156 NA NA NA NA NA NA 9943 XM_044328912.1 1419 1083 846 1058 1693 Q4U2V3 0 Cytosolic carboxypeptidase 1 (EC 3.4.17.-) (EC 3.4.17.24) (ATP/GTP-binding protein 1) (Protein deglutamylase CCP1) Danio rerio (Zebrafish) (Brachydanio rerio) C-terminal protein deglutamylation [GO:0035609]; cerebellar Purkinje cell differentiation [GO:0021702]; chordate embryonic development [GO:0043009]; eye photoreceptor cell differentiation [GO:0001754]; mitochondrion organization [GO:0007005]; neuromuscular process [GO:0050905]; olfactory bulb development [GO:0021772]; protein side chain deglutamylation [GO:0035610]; proteolysis [GO:0006508]; T cell differentiation in thymus [GO:0033077] GO:0001754; GO:0004181; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0006508; GO:0007005; GO:0008270; GO:0015631; GO:0021702; GO:0021772; GO:0033077; GO:0035609; GO:0035610; GO:0043009; GO:0050905 9944 XM_029346909.2 32 4 17 10 167 NA NA NA NA NA NA 9945 XR_006392623.1 43 38 5 32 40 NA NA NA NA NA NA 9946 XM_044314056.1 45 73 12 44 127 NA NA NA NA NA NA 9947 XM_029342198.2 4410 1513 747 2302 2494 Q64424 8.77e-79 Pancreatic lipase-related protein 2 (PL-RP2) (Cytotoxic T lymphocyte lipase) (Galactolipase) (EC 3.1.1.26) (Triacylglycerol lipase) (EC 3.1.1.3) Myocastor coypus (Coypu) (Nutria) galactolipid catabolic process [GO:0019376]; phosphatidylcholine catabolic process [GO:0034638]; phospholipid catabolic process [GO:0009395]; phospholipid metabolic process [GO:0006644]; triglyceride catabolic process [GO:0019433] GO:0004620; GO:0004806; GO:0005509; GO:0005615; GO:0006644; GO:0009395; GO:0016020; GO:0019376; GO:0019433; GO:0031410; GO:0034638; GO:0043005; GO:0047372; GO:0047714; GO:0102549 9948 XM_029326431.2 490 272 331 389 461 D3Z8N4 0 Kelch-like protein 20 Rattus norvegicus (Rat) Golgi to endosome transport [GO:0006895]; negative regulation of apoptotic process [GO:0043066]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K33-linked ubiquitination [GO:1990390]; protein transport [GO:0015031]; protein ubiquitination [GO:0016567] GO:0003779; GO:0004842; GO:0005737; GO:0005802; GO:0005829; GO:0006895; GO:0015031; GO:0016567; GO:0016605; GO:0019964; GO:0030424; GO:0030425; GO:0031463; GO:0043066; GO:0043161; GO:0048471; GO:1990390 9949 XM_044312990.1 30 13 1 3 10 Q6IQ73 7.33e-21 Charged multivesicular body protein 4c (Chromatin-modifying protein 4c) (CHMP4c) Danio rerio (Zebrafish) (Brachydanio rerio) abscission [GO:0009838]; cilium assembly [GO:0060271]; late endosome to vacuole transport via multivesicular body sorting pathway [GO:0032511]; mitotic cytokinesis checkpoint signaling [GO:0044878]; negative regulation of cytokinesis [GO:0032466]; protein transport [GO:0015031]; vesicle budding from membrane [GO:0006900] GO:0000815; GO:0005771; GO:0005829; GO:0006900; GO:0009838; GO:0009898; GO:0015031; GO:0031902; GO:0032466; GO:0032511; GO:0044878; GO:0060271 9950 XM_044324254.1 692 300 683 1528 930 P0C6B8 0 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 9951 XM_044324254.1 692 300 683 1528 930 P0C6B8 0 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 9952 XM_044324254.1 692 300 683 1528 930 P0C6B8 0 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 9953 XM_044324254.1 692 300 683 1528 930 P0C6B8 0 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 9954 XM_044324254.1 692 300 683 1528 930 P0C6B8 0 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 9955 XM_044324254.1 692 300 683 1528 930 P0C6B8 0 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 9956 XM_044324254.1 692 300 683 1528 930 P0C6B8 0 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 9957 XM_044324254.1 692 300 683 1528 930 P0C6B8 0 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 9958 XM_044324254.1 692 300 683 1528 930 P0C6B8 0 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 9959 XM_044324254.1 692 300 683 1528 930 P0C6B8 0 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 9960 XM_044324254.1 692 300 683 1528 930 P0C6B8 0 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 9961 XM_044324254.1 692 300 683 1528 930 P0C6B8 0 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 9962 XM_044324254.1 692 300 683 1528 930 P0C6B8 8.34e-180 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 9963 XM_044324254.1 692 300 683 1528 930 P0C6B8 2.2e-152 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 9964 XM_044324254.1 692 300 683 1528 930 P0C6B8 1.41e-71 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 9965 XM_029341327.2 540 250 312 512 463 Q8R418 4.56e-84 Endoribonuclease Dicer (EC 3.1.26.3) (Double-strand-specific ribonuclease mDCR-1) Mus musculus (Mouse) anatomical structure development [GO:0048856]; angiogenesis [GO:0001525]; apoptotic DNA fragmentation [GO:0006309]; branching morphogenesis of an epithelial tube [GO:0048754]; cardiac muscle cell development [GO:0055013]; cardiac neural crest cell development involved in outflow tract morphogenesis [GO:0061309]; cartilage development [GO:0051216]; cell population proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; defense response to virus [GO:0051607]; digestive tract development [GO:0048565]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; epidermis morphogenesis [GO:0048730]; ganglion development [GO:0061548]; gene expression [GO:0010467]; global gene silencing by mRNA cleavage [GO:0098795]; hair follicle cell proliferation [GO:0071335]; hair follicle development [GO:0001942]; hair follicle morphogenesis [GO:0031069]; inner ear receptor cell development [GO:0060119]; intestinal epithelial cell development [GO:0060576]; lung development [GO:0030324]; meiotic spindle organization [GO:0000212]; miRNA processing [GO:0035196]; mRNA stabilization [GO:0048255]; multicellular organism growth [GO:0035264]; myoblast differentiation involved in skeletal muscle regeneration [GO:0014835]; negative regulation of gene expression [GO:0010629]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of Schwann cell proliferation [GO:0010626]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of tumor necrosis factor production [GO:0032720]; nerve development [GO:0021675]; neuron projection morphogenesis [GO:0048812]; NIK/NF-kappaB signaling [GO:0038061]; olfactory bulb interneuron differentiation [GO:0021889]; pericentric heterochromatin formation [GO:0031508]; peripheral nervous system myelin formation [GO:0032290]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904906]; positive regulation of establishment of endothelial barrier [GO:1903142]; positive regulation of gene expression [GO:0010628]; positive regulation of hepatic stellate cell proliferation [GO:1904899]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of myelination [GO:0031643]; positive regulation of Schwann cell differentiation [GO:0014040]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; post-embryonic development [GO:0009791]; pre-miRNA processing [GO:0031054]; regulation of cell cycle [GO:0051726]; regulation of enamel mineralization [GO:0070173]; regulation of epithelial cell differentiation [GO:0030856]; regulation of gene expression [GO:0010468]; regulation of inflammatory response [GO:0050727]; regulation of miRNA metabolic process [GO:2000628]; regulation of muscle cell apoptotic process [GO:0010660]; regulation of myelination [GO:0031641]; regulation of neurogenesis [GO:0050767]; regulation of neuron differentiation [GO:0045664]; regulation of Notch signaling pathway [GO:0008593]; regulation of odontogenesis of dentin-containing tooth [GO:0042487]; regulation of oligodendrocyte differentiation [GO:0048713]; regulation of protein phosphorylation [GO:0001932]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of RNA metabolic process [GO:0051252]; regulation of stem cell differentiation [GO:2000736]; regulation of viral genome replication [GO:0045069]; reproductive structure development [GO:0048608]; RISC complex assembly [GO:0070922]; RNA phosphodiester bond hydrolysis [GO:0090501]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; RNA processing [GO:0006396]; RNA-mediated post-transcriptional gene silencing [GO:0035194]; rRNA processing [GO:0006364]; siRNA processing [GO:0030422]; spermatogonial cell division [GO:0007284]; spinal cord motor neuron differentiation [GO:0021522]; spindle assembly [GO:0051225]; spleen development [GO:0048536]; stem cell population maintenance [GO:0019827]; trophectodermal cell proliferation [GO:0001834]; zygote asymmetric cell division [GO:0010070] GO:0000122; GO:0000212; GO:0001525; GO:0001834; GO:0001932; GO:0001942; GO:0003677; GO:0003723; GO:0003725; GO:0004386; GO:0004521; GO:0004525; GO:0004530; GO:0005524; GO:0005634; GO:0005737; GO:0005783; GO:0005793; GO:0005829; GO:0006309; GO:0006364; GO:0006396; GO:0007284; GO:0008283; GO:0008593; GO:0009791; GO:0010070; GO:0010467; GO:0010468; GO:0010595; GO:0010626; GO:0010628; GO:0010629; GO:0010660; GO:0014040; GO:0014835; GO:0016442; GO:0019827; GO:0019904; GO:0021522; GO:0021675; GO:0021889; GO:0021987; GO:0030324; GO:0030326; GO:0030422; GO:0030424; GO:0030425; GO:0030426; GO:0030856; GO:0031054; GO:0031069; GO:0031508; GO:0031641; GO:0031643; GO:0032290; GO:0032720; GO:0032967; GO:0035116; GO:0035194; GO:0035196; GO:0035197; GO:0035198; GO:0035264; GO:0038061; GO:0042487; GO:0045069; GO:0045589; GO:0045664; GO:0045944; GO:0046872; GO:0048255; GO:0048471; GO:0048536; GO:0048565; GO:0048608; GO:0048713; GO:0048730; GO:0048754; GO:0048812; GO:0048856; GO:0050727; GO:0050767; GO:0051216; GO:0051225; GO:0051252; GO:0051607; GO:0051726; GO:0055013; GO:0060119; GO:0060253; GO:0060576; GO:0061309; GO:0061548; GO:0070062; GO:0070173; GO:0070578; GO:0070883; GO:0070922; GO:0071335; GO:0090501; GO:0090502; GO:0098795; GO:0098978; GO:0099092; GO:1903142; GO:1904899; GO:1904906; GO:1905564; GO:2000628; GO:2000630; GO:2000736 9966 XM_029341327.2 540 250 312 512 463 Q8R418 4.99e-58 Endoribonuclease Dicer (EC 3.1.26.3) (Double-strand-specific ribonuclease mDCR-1) Mus musculus (Mouse) anatomical structure development [GO:0048856]; angiogenesis [GO:0001525]; apoptotic DNA fragmentation [GO:0006309]; branching morphogenesis of an epithelial tube [GO:0048754]; cardiac muscle cell development [GO:0055013]; cardiac neural crest cell development involved in outflow tract morphogenesis [GO:0061309]; cartilage development [GO:0051216]; cell population proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; defense response to virus [GO:0051607]; digestive tract development [GO:0048565]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; epidermis morphogenesis [GO:0048730]; ganglion development [GO:0061548]; gene expression [GO:0010467]; global gene silencing by mRNA cleavage [GO:0098795]; hair follicle cell proliferation [GO:0071335]; hair follicle development [GO:0001942]; hair follicle morphogenesis [GO:0031069]; inner ear receptor cell development [GO:0060119]; intestinal epithelial cell development [GO:0060576]; lung development [GO:0030324]; meiotic spindle organization [GO:0000212]; miRNA processing [GO:0035196]; mRNA stabilization [GO:0048255]; multicellular organism growth [GO:0035264]; myoblast differentiation involved in skeletal muscle regeneration [GO:0014835]; negative regulation of gene expression [GO:0010629]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of Schwann cell proliferation [GO:0010626]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of tumor necrosis factor production [GO:0032720]; nerve development [GO:0021675]; neuron projection morphogenesis [GO:0048812]; NIK/NF-kappaB signaling [GO:0038061]; olfactory bulb interneuron differentiation [GO:0021889]; pericentric heterochromatin formation [GO:0031508]; peripheral nervous system myelin formation [GO:0032290]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904906]; positive regulation of establishment of endothelial barrier [GO:1903142]; positive regulation of gene expression [GO:0010628]; positive regulation of hepatic stellate cell proliferation [GO:1904899]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of myelination [GO:0031643]; positive regulation of Schwann cell differentiation [GO:0014040]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; post-embryonic development [GO:0009791]; pre-miRNA processing [GO:0031054]; regulation of cell cycle [GO:0051726]; regulation of enamel mineralization [GO:0070173]; regulation of epithelial cell differentiation [GO:0030856]; regulation of gene expression [GO:0010468]; regulation of inflammatory response [GO:0050727]; regulation of miRNA metabolic process [GO:2000628]; regulation of muscle cell apoptotic process [GO:0010660]; regulation of myelination [GO:0031641]; regulation of neurogenesis [GO:0050767]; regulation of neuron differentiation [GO:0045664]; regulation of Notch signaling pathway [GO:0008593]; regulation of odontogenesis of dentin-containing tooth [GO:0042487]; regulation of oligodendrocyte differentiation [GO:0048713]; regulation of protein phosphorylation [GO:0001932]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of RNA metabolic process [GO:0051252]; regulation of stem cell differentiation [GO:2000736]; regulation of viral genome replication [GO:0045069]; reproductive structure development [GO:0048608]; RISC complex assembly [GO:0070922]; RNA phosphodiester bond hydrolysis [GO:0090501]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; RNA processing [GO:0006396]; RNA-mediated post-transcriptional gene silencing [GO:0035194]; rRNA processing [GO:0006364]; siRNA processing [GO:0030422]; spermatogonial cell division [GO:0007284]; spinal cord motor neuron differentiation [GO:0021522]; spindle assembly [GO:0051225]; spleen development [GO:0048536]; stem cell population maintenance [GO:0019827]; trophectodermal cell proliferation [GO:0001834]; zygote asymmetric cell division [GO:0010070] GO:0000122; GO:0000212; GO:0001525; GO:0001834; GO:0001932; GO:0001942; GO:0003677; GO:0003723; GO:0003725; GO:0004386; GO:0004521; GO:0004525; GO:0004530; GO:0005524; GO:0005634; GO:0005737; GO:0005783; GO:0005793; GO:0005829; GO:0006309; GO:0006364; GO:0006396; GO:0007284; GO:0008283; GO:0008593; GO:0009791; GO:0010070; GO:0010467; GO:0010468; GO:0010595; GO:0010626; GO:0010628; GO:0010629; GO:0010660; GO:0014040; GO:0014835; GO:0016442; GO:0019827; GO:0019904; GO:0021522; GO:0021675; GO:0021889; GO:0021987; GO:0030324; GO:0030326; GO:0030422; GO:0030424; GO:0030425; GO:0030426; GO:0030856; GO:0031054; GO:0031069; GO:0031508; GO:0031641; GO:0031643; GO:0032290; GO:0032720; GO:0032967; GO:0035116; GO:0035194; GO:0035196; GO:0035197; GO:0035198; GO:0035264; GO:0038061; GO:0042487; GO:0045069; GO:0045589; GO:0045664; GO:0045944; GO:0046872; GO:0048255; GO:0048471; GO:0048536; GO:0048565; GO:0048608; GO:0048713; GO:0048730; GO:0048754; GO:0048812; GO:0048856; GO:0050727; GO:0050767; GO:0051216; GO:0051225; GO:0051252; GO:0051607; GO:0051726; GO:0055013; GO:0060119; GO:0060253; GO:0060576; GO:0061309; GO:0061548; GO:0070062; GO:0070173; GO:0070578; GO:0070883; GO:0070922; GO:0071335; GO:0090501; GO:0090502; GO:0098795; GO:0098978; GO:0099092; GO:1903142; GO:1904899; GO:1904906; GO:1905564; GO:2000628; GO:2000630; GO:2000736 9967 XM_044319223.1 1097 746 517 719 562 NA NA NA NA NA NA 9968 XR_006395160.1 3 9 11 15 11 NA NA NA NA NA NA 9969 XR_006397584.1 22 16 18 27 17 Q0VCA2 6.45e-30 Arrestin domain-containing protein 3 Bos taurus (Bovine) fat pad development [GO:0060613]; heat generation [GO:0031649]; negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071878]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of heat generation [GO:0031651]; negative regulation of locomotion involved in locomotory behavior [GO:0090327]; positive regulation of hippo signaling [GO:0035332]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein transport [GO:0015031]; skin development [GO:0043588] GO:0005737; GO:0005764; GO:0005768; GO:0005769; GO:0005886; GO:0015031; GO:0031649; GO:0031651; GO:0031699; GO:0035332; GO:0043588; GO:0051443; GO:0060613; GO:0071878; GO:0090327; GO:0120163 9970 XM_029338838.2 0 0 0 25 12 O75899 9.85e-139 Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51) (HG20) Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway [GO:0007186]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; neuron-glial cell signaling [GO:0150099]; synaptic transmission, GABAergic [GO:0051932] GO:0004888; GO:0004965; GO:0005737; GO:0005886; GO:0007186; GO:0007193; GO:0007194; GO:0007214; GO:0007268; GO:0038039; GO:0043005; GO:0045211; GO:0046982; GO:0051932; GO:0150099; GO:1902710; GO:1902712 9971 XR_006394377.1 156 125 119 110 245 NA NA NA NA NA NA 9972 XR_006398186.1 35 59 25 71 41 Q5RBG4 2.45e-171 Histone acetyltransferase KAT5 (EC 2.3.1.48) (60 kDa Tat-interactive protein) (Tip60) (Histone acetyltransferase HTATIP) (Lysine acetyltransferase 5) (Protein 2-hydroxyisobutyryltransferase KAT5) (EC 2.3.1.-) (Protein acetyltransferase KAT5) (EC 2.3.1.-) (Protein crotonyltransferase KAT5) (EC 2.3.1.-) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cellular response to DNA damage stimulus [GO:0006974]; cellular response to glucose starvation [GO:0042149]; chromatin organization [GO:0006325]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; establishment of mitotic spindle orientation [GO:0000132]; histone acetylation [GO:0016573]; innate immune response [GO:0045087]; lipid droplet disassembly [GO:1905691]; nucleotide-excision repair [GO:0006289]; peptidyl-lysine acetylation [GO:0018394]; positive regulation of attachment of mitotic spindle microtubules to kinetochore [GO:1902425]; positive regulation of autophagy [GO:0010508]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of mitotic sister chromatid segregation [GO:0062033]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of regulatory T cell differentiation [GO:0045591]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of triglyceride biosynthetic process [GO:0010867]; regulation of hematopoietic stem cell differentiation [GO:1902036]; spermatid development [GO:0007286] GO:0000132; GO:0000724; GO:0000776; GO:0000812; GO:0000922; GO:0003682; GO:0003713; GO:0004402; GO:0005634; GO:0005730; GO:0005737; GO:0006289; GO:0006302; GO:0006325; GO:0006974; GO:0006978; GO:0007286; GO:0010508; GO:0010867; GO:0016573; GO:0018394; GO:0032777; GO:0035267; GO:0042149; GO:0042753; GO:0043998; GO:0045087; GO:0045591; GO:0045663; GO:0045893; GO:0045944; GO:0046872; GO:0048471; GO:0061733; GO:0062033; GO:0106226; GO:0140064; GO:0140065; GO:1902036; GO:1902425; GO:1905168; GO:1905691 9973 XM_029327109.2 0 31 6 0 1 NA NA NA NA NA NA 9974 XM_029346858.2 29 174 209 0 276 Q8BWN8 2.32e-77 Peroxisomal succinyl-coenzyme A thioesterase (EC 3.1.2.3) (Acyl-coenzyme A thioesterase 4) (Acyl-CoA thioesterase 4) (PTE-2b) (Peroxisomal acyl coenzyme A thioester hydrolase Ib) (Peroxisomal long-chain acyl-CoA thioesterase Ib) (PTE-Ib) Mus musculus (Mouse) acyl-CoA metabolic process [GO:0006637]; dicarboxylic acid catabolic process [GO:0043649]; dicarboxylic acid metabolic process [GO:0043648]; fatty acid metabolic process [GO:0006631]; long-chain fatty acid metabolic process [GO:0001676]; saturated monocarboxylic acid metabolic process [GO:0032788]; short-chain fatty acid metabolic process [GO:0046459]; succinyl-CoA metabolic process [GO:0006104]; unsaturated monocarboxylic acid metabolic process [GO:0032789]; very long-chain fatty acid metabolic process [GO:0000038] GO:0000038; GO:0001676; GO:0004778; GO:0005777; GO:0006104; GO:0006631; GO:0006637; GO:0032788; GO:0032789; GO:0043648; GO:0043649; GO:0044466; GO:0046459; GO:0047617 9975 XR_006397207.1 0 0 0 14 0 NA NA NA NA NA NA 9976 XM_029326786.2 33 88 16 109 50 NA NA NA NA NA NA 9977 XM_044312191.1 21 38 13 37 103 Q9VBW3 6.27e-82 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 9978 XM_029341172.2 0 0 0 11 7 P48039 3.06e-25 Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor) Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; circadian rhythm [GO:0007623]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; mating behavior [GO:0007617] GO:0004930; GO:0005886; GO:0007186; GO:0007187; GO:0007193; GO:0007617; GO:0007623; GO:0008502; GO:0042562; GO:0043235; GO:0097159 9979 XM_029356833.2 1292 1347 830 1496 1398 NA NA NA NA NA NA 9980 XR_006391863.1 5 0 10 12 26 NA NA NA NA NA NA 9981 XR_003824108.2 189 160 125 257 235 NA NA NA NA NA NA 9982 XM_044308147.1 3 14 0 4 5 Q9SAL0 2.63e-81 E3 ubiquitin-protein ligase RGLG4 (EC 2.3.2.27) (RING domain ligase 4) Arabidopsis thaliana (Mouse-ear cress) defense response to bacterium [GO:0042742]; jasmonic acid mediated signaling pathway [GO:0009867]; protein K63-linked ubiquitination [GO:0070534]; response to wounding [GO:0009611] GO:0004842; GO:0005634; GO:0005737; GO:0005739; GO:0009611; GO:0009867; GO:0042742; GO:0046872; GO:0061630; GO:0070534 9983 XM_029325368.2 101 141 153 78 141 Q9Y226 1.7e-63 Solute carrier family 22 member 13 (Organic anion transporter 10) (OAT10) (Organic cation transporter-like 3) (ORCTL-3) (ORCTL3) Homo sapiens (Human) NAD biosynthesis via nicotinamide riboside salvage pathway [GO:0034356]; negative regulation of fatty acid metabolic process [GO:0045922]; nicotinate transport [GO:2001142]; positive regulation of T cell mediated cytotoxicity directed against tumor cell target [GO:0002854]; urate transport [GO:0015747] GO:0002854; GO:0005783; GO:0005794; GO:0005886; GO:0015143; GO:0015747; GO:0016324; GO:0034356; GO:0045922; GO:0070062; GO:0090416; GO:2001142 9984 XM_029325775.2 12 4 0 0 44 NA NA NA NA NA NA 9985 XM_029327774.2 126 77 0 352 103 NA NA NA NA NA NA 9986 XM_029329725.2 95 20 32 38 32 Q8N6U8 5.48e-30 G-protein coupled receptor 161 (G-protein coupled receptor RE2) Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:1901621] GO:0004930; GO:0005929; GO:0007186; GO:0007189; GO:0030666; GO:0043005; GO:0055037; GO:0060170; GO:0097386; GO:1901621 9987 XM_044315969.1 4 0 39 65 246 NA NA NA NA NA NA 9988 XR_006396502.1 276 283 168 195 214 NA NA NA NA NA NA 9989 XM_029332373.2 20 0 0 10 33 Q3V050 7.76e-73 Multidrug and toxin extrusion protein 2 (MATE-2) (mMATE-2) (H(+)/organic cation antiporter kidney-specific) (Solute carrier family 47 member 2) Mus musculus (Mouse) organic cation transport [GO:0015695]; xenobiotic detoxification by transmembrane export across the plasma membrane [GO:1990961] GO:0005886; GO:0015101; GO:0015179; GO:0015297; GO:0015299; GO:0015695; GO:0016020; GO:0016323; GO:0016324; GO:0022857; GO:0042910; GO:0061459; GO:1990961 9990 XM_029355748.2 212 47 91 62 80 P24044 1.09e-47 Calmodulin Plasmodium falciparum NA GO:0005509; GO:0005737; GO:0020007 9991 XM_044319091.1 135 22 39 102 44 Q6ZQ11 3.55e-180 Chondroitin sulfate synthase 1 (EC 2.4.1.175) (EC 2.4.1.226) (Chondroitin glucuronyltransferase 1) (Chondroitin synthase 1) (ChSy-1) (Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1) (N-acetylgalactosaminyltransferase 1) Mus musculus (Mouse) bone morphogenesis [GO:0060349]; cartilage development [GO:0051216]; chondrocyte development [GO:0002063]; chondroitin sulfate biosynthetic process [GO:0030206]; negative regulation of ossification [GO:0030279]; positive regulation of smoothened signaling pathway [GO:0045880]; proximal/distal pattern formation [GO:0009954]; response to nutrient levels [GO:0031667]; sulfation [GO:0051923] GO:0002063; GO:0005576; GO:0005794; GO:0008376; GO:0009954; GO:0016757; GO:0030206; GO:0030279; GO:0031667; GO:0032580; GO:0045880; GO:0046872; GO:0047238; GO:0050510; GO:0051216; GO:0051923; GO:0060349 9992 XM_029351412.2 4387 2788 2395 4578 3987 O60282 0 Kinesin heavy chain isoform 5C (EC 3.6.4.-) (Kinesin heavy chain neuron-specific 2) (Kinesin-1) Homo sapiens (Human) anterograde axonal protein transport [GO:0099641]; anterograde dendritic transport of neurotransmitter receptor complex [GO:0098971]; axon guidance [GO:0007411]; cytoskeleton-dependent intracellular transport [GO:0030705]; microtubule-based movement [GO:0007018]; motor neuron axon guidance [GO:0008045]; mRNA transport [GO:0051028]; organelle organization [GO:0006996]; synaptic vesicle transport [GO:0048489] GO:0003777; GO:0005524; GO:0005871; GO:0005874; GO:0006996; GO:0007018; GO:0007411; GO:0008017; GO:0008045; GO:0008574; GO:0016887; GO:0030705; GO:0032839; GO:0035253; GO:0043025; GO:0044295; GO:0048489; GO:0051028; GO:0098971; GO:0099641; GO:0150034; GO:1904115 9993 XM_044320994.1 78 8 0 58 71 NA NA NA NA NA NA 9994 XM_029348644.2 23 1 6 6 26 NA NA NA NA NA NA 9995 XM_029344908.2 854 781 475 1618 787 O62839 0 Catalase (EC 1.11.1.6) Sus scrofa (Pig) hydrogen peroxide catabolic process [GO:0042744]; positive regulation of cell division [GO:0051781]; response to hydrogen peroxide [GO:0042542] GO:0004096; GO:0005737; GO:0005739; GO:0005777; GO:0020037; GO:0042542; GO:0042744; GO:0046872; GO:0051781 9996 XM_044319448.1 11 5 35 9 54 NA NA NA NA NA NA 9997 XM_029334841.2 39 72 37 16 62 NA NA NA NA NA NA 9998 XM_029332038.2 74 772 72 80 77 Q8NFZ3 3.18e-83 Neuroligin-4, Y-linked (Neuroligin Y) Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; learning [GO:0007612]; modulation of chemical synaptic transmission [GO:0050804]; neuron cell-cell adhesion [GO:0007158]; postsynaptic membrane assembly [GO:0097104]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; social behavior [GO:0035176]; synaptic vesicle endocytosis [GO:0048488]; vocalization behavior [GO:0071625] GO:0005886; GO:0007158; GO:0007268; GO:0007612; GO:0009986; GO:0016020; GO:0035176; GO:0038023; GO:0042043; GO:0045202; GO:0048488; GO:0050804; GO:0050839; GO:0071625; GO:0097104; GO:0097105; GO:0097110; GO:0098793; GO:0098839; GO:0098983; GO:0098985; GO:0099054; GO:0099634 9999 XM_044322111.1 759 294 293 494 350 Q5RC70 9.8e-169 DnaJ homolog subfamily C member 11 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cristae formation [GO:0042407] GO:0001401; GO:0016607; GO:0042407; GO:0061617 10000 XM_029340965.2 170 18 28 415 253 Q9TRC7 0 Amiloride-sensitive amine oxidase [copper-containing] (DAO) (Diamine oxidase) (EC 1.4.3.22) (Amiloride-binding protein 1) (Amine oxidase copper domain-containing protein 1) (Histaminase) Sus scrofa (Pig) amine metabolic process [GO:0009308]; cellular response to azide [GO:0097185]; cellular response to copper ion [GO:0071280]; cellular response to copper ion starvation [GO:0035874]; cellular response to histamine [GO:0071420]; putrescine metabolic process [GO:0009445]; response to antibiotic [GO:0046677] GO:0005507; GO:0005509; GO:0005615; GO:0005886; GO:0005923; GO:0008131; GO:0008201; GO:0008270; GO:0009308; GO:0009445; GO:0035874; GO:0042803; GO:0044877; GO:0046677; GO:0048038; GO:0052597; GO:0052598; GO:0052599; GO:0052600; GO:0070062; GO:0071280; GO:0071420; GO:0097185 10001 XM_029343372.2 19 167 0 0 0 NA NA NA NA NA NA 10002 XM_029355543.2 19 26 28 87 59 NA NA NA NA NA NA 10003 XM_029351212.2 13 0 0 6 0 NA NA NA NA NA NA 10004 XR_006393724.1 6 12 0 11 15 NA NA NA NA NA NA 10005 XM_044322084.1 143 200 185 350 304 B1AJZ9 4.15e-28 Forkhead-associated domain-containing protein 1 (FHA domain-containing protein 1) Homo sapiens (Human) NA NA 10006 XM_044322084.1 143 200 185 350 304 B1AJZ9 2.04e-26 Forkhead-associated domain-containing protein 1 (FHA domain-containing protein 1) Homo sapiens (Human) NA NA 10007 XM_029349479.2 347 0 109 0 258 A0A0G2JDV3 1.01e-31 Guanylate-binding protein 6 (EC 3.6.5.-) (GTP-binding protein 6) (GBP-6) (Guanine nucleotide-binding protein 6) (Macrophage activation 2 like protein) Mus musculus (Mouse) adhesion of symbiont to host [GO:0044406]; cellular response to interferon-beta [GO:0035458]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; defense response to Gram-positive bacterium [GO:0050830]; defense response to protozoan [GO:0042832]; response to bacterium [GO:0009617] GO:0003924; GO:0005525; GO:0009617; GO:0020005; GO:0031410; GO:0035458; GO:0042832; GO:0044406; GO:0050830; GO:0071222; GO:0071346 10008 XM_029341810.2 81 58 53 34 23 NA NA NA NA NA NA 10009 XM_029338735.2 29 0 0 0 0 Q9BVH7 5.17e-24 Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 (EC 2.4.99.-) (GD1 alpha synthase) (GalNAc alpha-2,6-sialyltransferase V) (ST6GalNAc V) (ST6GalNAcV) (Sialyltransferase 7E) (SIAT7-E) Homo sapiens (Human) ganglioside biosynthetic process [GO:0001574]; glycosphingolipid biosynthetic process [GO:0006688]; oligosaccharide biosynthetic process [GO:0009312]; oligosaccharide metabolic process [GO:0009311]; protein glycosylation [GO:0006486] GO:0000139; GO:0001574; GO:0001665; GO:0006486; GO:0006688; GO:0008373; GO:0009311; GO:0009312 10010 XM_044308569.1 62 20 0 7 6 NA NA NA NA NA NA 10011 XM_044321893.1 818 534 330 565 705 NA NA NA NA NA NA 10012 XM_044312225.1 391 65 183 182 49 NA NA NA NA NA NA 10013 XM_029337676.2 364 8 150 35 0 Q9ESJ0 0 Exportin-4 (Exp4) Mus musculus (Mouse) positive regulation of protein export from nucleus [GO:0046827]; protein export from nucleus [GO:0006611] GO:0005049; GO:0005643; GO:0005654; GO:0005737; GO:0005829; GO:0006611; GO:0046827 10014 XR_006394573.1 69 107 16 33 27 NA NA NA NA NA NA 10015 XM_044310867.1 123 0 0 83 90 NA NA NA NA NA NA 10016 XM_029346079.2 1067 380 520 386 317 Q2TBG7 2.72e-37 Iron-sulfur cluster assembly 2 homolog, mitochondrial (HESB-like domain-containing protein 1) Bos taurus (Bovine) iron-sulfur cluster assembly [GO:0016226]; protein maturation by [4Fe-4S] cluster transfer [GO:0106035] GO:0005506; GO:0005739; GO:0016226; GO:0042802; GO:0051537; GO:0051539; GO:0106035 10017 XM_044319124.1 719 0 1296 0 0 NA NA NA NA NA NA 10018 XM_044315898.1 0 8 0 0 0 NA NA NA NA NA NA 10019 XR_006391548.1 28 3 50 3 108 NA NA NA NA NA NA 10020 XM_029344934.2 738 637 523 637 465 Q9Y315 7.51e-161 Deoxyribose-phosphate aldolase (DERA) (EC 4.1.2.4) (2-deoxy-D-ribose 5-phosphate aldolase) (Phosphodeoxyriboaldolase) (Deoxyriboaldolase) Homo sapiens (Human) carbohydrate catabolic process [GO:0016052]; deoxyribonucleoside catabolic process [GO:0046121]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]; pentose-phosphate shunt [GO:0006098] GO:0004139; GO:0005576; GO:0005654; GO:0005829; GO:0006098; GO:0009264; GO:0016052; GO:0034774; GO:0046121; GO:0046386; GO:1904813 10021 XM_029350346.2 129 90 90 96 324 NA NA NA NA NA NA 10022 XM_029327559.2 1 0 0 0 41 Q9JI67 1.92e-29 Beta-1,3-galactosyltransferase 5 (Beta-1,3-GalTase 5) (Beta3Gal-T5) (Beta3GalT5) (b3Gal-T5) (EC 2.4.1.-) (Beta-3-Gx-T5) (Stage-specific embryonic antigen 3 synthase) (SSEA-3 synthase) (UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 5) (UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 5) Mus musculus (Mouse) lipid metabolic process [GO:0006629]; protein glycosylation [GO:0006486]; response to bacterium [GO:0009617] GO:0000139; GO:0006486; GO:0006629; GO:0008194; GO:0008499; GO:0009617; GO:0016757 10023 XM_029324294.2 1 4 11 6 5 NA NA NA NA NA NA 10024 XM_029328908.2 286 93 48 0 0 NA NA NA NA NA NA 10025 XM_029348862.2 154 61 66 130 13 P31646 0 Sodium- and chloride-dependent GABA transporter 2 (GAT-2) (Solute carrier family 6 member 13) Rattus norvegicus (Rat) amino acid import across plasma membrane [GO:0089718]; creatine transmembrane transport [GO:0015881]; gamma-aminobutyric acid import [GO:0051939]; monocarboxylic acid transport [GO:0015718]; neurotransmitter transport [GO:0006836]; nitrogen compound transport [GO:0071705]; positive regulation of necrotic cell death [GO:0010940]; sodium ion transmembrane transport [GO:0035725]; taurine transport [GO:0015734] GO:0005283; GO:0005308; GO:0005332; GO:0005368; GO:0005369; GO:0005886; GO:0006836; GO:0008028; GO:0010940; GO:0015171; GO:0015185; GO:0015718; GO:0015734; GO:0015881; GO:0016323; GO:0035725; GO:0042165; GO:0043005; GO:0051939; GO:0071705; GO:0089718 10026 XM_044313364.1 15 11 590 23 132 NA NA NA NA NA NA 10027 XM_044322799.1 24 18 11 0 24 NA NA NA NA NA NA 10028 XM_044316229.1 128 158 47 63 90 Q96PM5 9.24e-56 RING finger and CHY zinc finger domain-containing protein 1 (EC 2.3.2.27) (Androgen receptor N-terminal-interacting protein) (CH-rich-interacting match with PLAG1) (E3 ubiquitin-protein ligase Pirh2) (RING finger protein 199) (RING-type E3 ubiquitin transferase RCHY1) (Zinc finger protein 363) (p53-induced RING-H2 protein) (hPirh2) Homo sapiens (Human) error-free translesion synthesis [GO:0070987]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; protein autoubiquitination [GO:0051865]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000151; GO:0002039; GO:0004842; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006511; GO:0008270; GO:0016567; GO:0016607; GO:0031398; GO:0032436; GO:0042803; GO:0043231; GO:0051865; GO:0061630; GO:0070987 10029 XR_006394294.1 39 8 39 8 45 NA NA NA NA NA NA 10030 XM_044309955.1 54 8 65 148 60 NA NA NA NA NA NA 10031 XM_029346179.2 353 1013 1885 3191 1012 Q94515 7.33e-123 Sphingolipid delta(4)-desaturase DES1 (EC 1.14.19.17) (Degenerative spermatocyte homolog 1) (DES-1) (Dihydroceramide desaturase-1) Drosophila melanogaster (Fruit fly) ceramide biosynthetic process [GO:0046513]; negative regulation of lipophagy [GO:1904503]; spermatogenesis [GO:0007283]; spindle assembly involved in male meiosis [GO:0007053] GO:0005739; GO:0005770; GO:0005783; GO:0005789; GO:0005886; GO:0007053; GO:0007283; GO:0016006; GO:0042284; GO:0046513; GO:0070938; GO:1904503 10032 XM_029347863.2 0 20 59 42 0 NA NA NA NA NA NA 10033 XM_029346109.2 10 1 4 0 0 P38571 1.5e-130 Lysosomal acid lipase/cholesteryl ester hydrolase (Acid cholesteryl ester hydrolase) (LAL) (EC 3.1.1.13) (Cholesteryl esterase) (Lipase A) (Sterol esterase) Homo sapiens (Human) cell morphogenesis [GO:0000902]; epithelial cell proliferation [GO:0050673]; homeostasis of number of cells within a tissue [GO:0048873]; inflammatory response [GO:0006954]; lipid catabolic process [GO:0016042]; low-density lipoprotein particle clearance [GO:0034383]; lung development [GO:0030324]; macrophage homeostasis [GO:0061519]; sterol metabolic process [GO:0016125]; tissue remodeling [GO:0048771] GO:0000902; GO:0001650; GO:0004771; GO:0005654; GO:0005764; GO:0005829; GO:0006954; GO:0016042; GO:0016125; GO:0016298; GO:0030324; GO:0034383; GO:0043202; GO:0043231; GO:0048771; GO:0048873; GO:0050673; GO:0061519 10034 XM_044319693.1 1 40 0 512 283 Q3V050 5.59e-88 Multidrug and toxin extrusion protein 2 (MATE-2) (mMATE-2) (H(+)/organic cation antiporter kidney-specific) (Solute carrier family 47 member 2) Mus musculus (Mouse) organic cation transport [GO:0015695]; xenobiotic detoxification by transmembrane export across the plasma membrane [GO:1990961] GO:0005886; GO:0015101; GO:0015179; GO:0015297; GO:0015299; GO:0015695; GO:0016020; GO:0016323; GO:0016324; GO:0022857; GO:0042910; GO:0061459; GO:1990961 10035 XM_044311245.1 1 2 1 7 0 NA NA NA NA NA NA 10036 XM_044308150.1 756 473 343 551 392 NA NA NA NA NA NA 10037 XM_044313249.1 161 579 681 786 794 Q5VV63 1.06e-124 Attractin-like protein 1 Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; G protein-coupled receptor signaling pathway [GO:0007186]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888] GO:0005604; GO:0007186; GO:0009887; GO:0009888; GO:0016020; GO:0016477; GO:0030246; GO:0034446 10038 XM_044313249.1 161 579 681 786 794 Q5VV63 1.06e-83 Attractin-like protein 1 Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; G protein-coupled receptor signaling pathway [GO:0007186]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888] GO:0005604; GO:0007186; GO:0009887; GO:0009888; GO:0016020; GO:0016477; GO:0030246; GO:0034446 10039 XM_044309921.1 6 0 19 4 245 NA NA NA NA NA NA 10040 XM_044310709.1 764 710 601 1361 324 O54991 9.88e-32 Contactin-associated protein 1 (Caspr) (Caspr1) (MHDNIV) (NCP1) (Neurexin IV) (Neurexin-4) (Paranodin) Mus musculus (Mouse) axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cytoskeleton organization [GO:0007010]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process [GO:0050905]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuronal action potential propagation [GO:0019227]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; postsynaptic density organization [GO:0097106]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; regulation of synapse maturation [GO:0090128] GO:0002175; GO:0005886; GO:0005918; GO:0007005; GO:0007010; GO:0007155; GO:0007409; GO:0016020; GO:0017124; GO:0019227; GO:0022010; GO:0022011; GO:0030424; GO:0030913; GO:0031175; GO:0033010; GO:0033270; GO:0042552; GO:0043209; GO:0048786; GO:0048812; GO:0050884; GO:0050885; GO:0050905; GO:0071205; GO:0090128; GO:0097106; GO:0098529; GO:0098978; GO:1990227 10041 XM_044306820.1 175 118 159 334 263 NA NA NA NA NA NA 10042 XM_044307799.1 0 0 36 0 0 Q7RTR2 1.1e-49 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 10043 XM_044307799.1 0 0 36 0 0 Q7RTR2 2.25e-49 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 10044 XM_044307799.1 0 0 36 0 0 Q7RTR2 1.58e-48 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 10045 XM_044307799.1 0 0 36 0 0 Q7RTR2 2.48e-45 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 10046 XM_044307799.1 0 0 36 0 0 Q7RTR2 5.18e-42 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 10047 XM_044307799.1 0 0 36 0 0 Q7RTR2 1.91e-36 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 10048 XM_044307799.1 0 0 36 0 0 Q7RTR2 3.25e-31 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 10049 XM_029357419.2 501 453 260 456 513 Q9D7A6 1.71e-28 Signal recognition particle 19 kDa protein (SRP19) Mus musculus (Mouse) SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition [GO:0006617] GO:0003723; GO:0005730; GO:0005786; GO:0005829; GO:0006617; GO:0008312; GO:0016604; GO:0043022; GO:0048500 10050 XM_029358311.2 0 0 0 35 0 Q9QYS2 0 Metabotropic glutamate receptor 3 (mGluR3) Mus musculus (Mouse) G protein-coupled glutamate receptor signaling pathway [GO:0007216]; gene expression [GO:0010467]; modulation of chemical synaptic transmission [GO:0050804]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; regulation of sensory perception of pain [GO:0051930]; regulation of synaptic transmission, glutamatergic [GO:0051966]; sensory perception of pain [GO:0019233]; synaptic transmission, glutamatergic [GO:0035249] GO:0001640; GO:0001641; GO:0005246; GO:0005886; GO:0007216; GO:0010467; GO:0014069; GO:0019233; GO:0030424; GO:0035249; GO:0042734; GO:0043005; GO:0043197; GO:0045211; GO:0048786; GO:0050804; GO:0051930; GO:0051966; GO:0097110; GO:0097449; GO:0098978; GO:0099170 10051 XR_006397799.1 56 0 112 48 176 NA NA NA NA NA NA 10052 XM_044324368.1 43 34 15 74 91 Q01433 0 AMP deaminase 2 (EC 3.5.4.6) (AMP deaminase isoform L) Homo sapiens (Human) AMP metabolic process [GO:0046033]; cyclic purine nucleotide metabolic process [GO:0052652]; energy homeostasis [GO:0097009]; IMP biosynthetic process [GO:0006188]; IMP salvage [GO:0032264] GO:0003876; GO:0005829; GO:0006188; GO:0032264; GO:0042802; GO:0046033; GO:0046872; GO:0052652; GO:0097009 10053 XM_029329804.2 245 161 165 252 470 Q8WV16 2.61e-39 DDB1- and CUL4-associated factor 4 (WD repeat-containing protein 21A) Homo sapiens (Human) protein ubiquitination [GO:0016567] GO:0005654; GO:0016567; GO:0080008 10054 XM_044307760.1 221 836 434 334 257 NA NA NA NA NA NA 10055 XM_029335660.2 67 3 9 39 23 B8VIU6 6.25e-23 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 10056 XM_044328067.1 6451 7372 3833 5238 4233 P40792 4.62e-114 Ras-related protein Rac1 Drosophila melanogaster (Fruit fly) actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; activation of protein kinase activity [GO:0032147]; axon extension [GO:0048675]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; axonal fasciculation [GO:0007413]; border follicle cell migration [GO:0007298]; cell competition in a multicellular organism [GO:0035212]; cell morphogenesis [GO:0000902]; cortical actin cytoskeleton organization [GO:0030866]; cortical cytoskeleton organization [GO:0030865]; dendrite development [GO:0016358]; determination of digestive tract left/right asymmetry [GO:0071907]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal closure, amnioserosa morphology change [GO:0046664]; dorsal closure, elongation of leading edge cells [GO:0007394]; dorsal closure, spreading of leading edge cells [GO:0007395]; embryonic anterior midgut (ectodermal) morphogenesis [GO:0048615]; encapsulation of foreign target [GO:0035010]; engulfment of apoptotic cell [GO:0043652]; establishment or maintenance of cell polarity [GO:0007163]; germ-band shortening [GO:0007390]; glial cell migration [GO:0008347]; head involution [GO:0008258]; hemocyte development [GO:0007516]; hemocyte migration [GO:0035099]; imaginal disc-derived wing hair site selection [GO:0035320]; immune response-regulating cell surface receptor signaling pathway involved in phagocytosis [GO:0002433]; JNK cascade [GO:0007254]; lamellipodium assembly [GO:0030032]; melanotic encapsulation of foreign target [GO:0035011]; memory [GO:0007613]; mesodermal cell migration [GO:0008078]; motor neuron axon guidance [GO:0008045]; muscle attachment [GO:0016203]; muscle cell development [GO:0055001]; myoblast fusion [GO:0007520]; myoblast proliferation [GO:0051450]; negative regulation of lamellipodium assembly [GO:0010593]; negative regulation of myotube cell migration [GO:0110125]; nephrocyte filtration [GO:0097206]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; open tracheal system development [GO:0007424]; peripheral nervous system development [GO:0007422]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669]; positive regulation of border follicle cell migration [GO:1903688]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of wound healing [GO:0090303]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of adherens junction organization [GO:1903391]; regulation of axonogenesis [GO:0050770]; regulation of cell shape [GO:0008360]; regulation of dendrite morphogenesis [GO:0048814]; regulation of locomotor rhythm [GO:1904059]; regulation of synapse assembly [GO:0051963]; regulation of synapse organization [GO:0050807]; response to wounding [GO:0009611]; rhabdomere development [GO:0042052]; salivary gland morphogenesis [GO:0007435]; sensory perception of touch [GO:0050975]; small GTPase mediated signal transduction [GO:0007264]; tracheal outgrowth, open tracheal system [GO:0007426]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; ventral cord development [GO:0007419] GO:0000902; GO:0001726; GO:0001954; GO:0002433; GO:0003924; GO:0005525; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0005938; GO:0007015; GO:0007163; GO:0007254; GO:0007264; GO:0007298; GO:0007390; GO:0007391; GO:0007394; GO:0007395; GO:0007411; GO:0007413; GO:0007419; GO:0007422; GO:0007424; GO:0007426; GO:0007435; GO:0007516; GO:0007520; GO:0007613; GO:0008045; GO:0008078; GO:0008258; GO:0008347; GO:0008360; GO:0009611; GO:0010593; GO:0016028; GO:0016199; GO:0016203; GO:0016358; GO:0019901; GO:0030032; GO:0030036; GO:0030865; GO:0030866; GO:0031175; GO:0031410; GO:0031532; GO:0032147; GO:0032794; GO:0032956; GO:0035010; GO:0035011; GO:0035099; GO:0035212; GO:0035320; GO:0042052; GO:0042995; GO:0043652; GO:0045773; GO:0046330; GO:0046664; GO:0046843; GO:0048010; GO:0048615; GO:0048675; GO:0048812; GO:0048814; GO:0050770; GO:0050807; GO:0050975; GO:0051017; GO:0051450; GO:0051491; GO:0051963; GO:0055001; GO:0071902; GO:0071907; GO:0090303; GO:0097206; GO:0110125; GO:1902669; GO:1903391; GO:1903688; GO:1904059 10057 XM_029348776.2 146 167 87 2058 119 Q9Y3E5 3.27e-55 Peptidyl-tRNA hydrolase 2, mitochondrial (PTH 2) (EC 3.1.1.29) (Bcl-2 inhibitor of transcription 1) Homo sapiens (Human) apoptotic process [GO:0006915]; negative regulation of anoikis [GO:2000811]; negative regulation of gene expression [GO:0010629]; positive regulation of anoikis [GO:2000210] GO:0004045; GO:0005739; GO:0005829; GO:0006915; GO:0010629; GO:0016020; GO:2000210; GO:2000811 10058 XM_044318359.1 125 5 63 200 18 NA NA NA NA NA NA 10059 XM_044310929.1 24 27 3 12 0 NA NA NA NA NA NA 10060 XM_029346678.2 4153 4032 2735 3593 3250 P28663 1.45e-125 Beta-soluble NSF attachment protein (SNAP-beta) (Brain protein I47) (N-ethylmaleimide-sensitive factor attachment protein beta) Mus musculus (Mouse) intracellular protein transport [GO:0006886]; protein-containing complex disassembly [GO:0032984]; regulation of ATP-dependent activity [GO:0043462]; regulation of receptor internalization [GO:0002090]; regulation of synaptic vesicle priming [GO:0010807]; SNARE complex disassembly [GO:0035494]; synaptic transmission, glutamatergic [GO:0035249]; synaptic vesicle endocytosis [GO:0048488] GO:0000149; GO:0002090; GO:0005483; GO:0006886; GO:0010807; GO:0019905; GO:0031201; GO:0032984; GO:0035249; GO:0035494; GO:0043209; GO:0043462; GO:0048488; GO:0048787; GO:0070044; GO:0098793; GO:0098794; GO:0098978 10061 XM_044315336.1 5 0 0 4 31 NA NA NA NA NA NA 10062 XM_029348553.2 0 39 0 36 0 Q9Z139 2.26e-123 Inactive tyrosine-protein kinase transmembrane receptor ROR1 (mROR1) (Neurotrophic tyrosine kinase, receptor-related 1) Mus musculus (Mouse) astrocyte development [GO:0014002]; inner ear development [GO:0048839]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of kinase activity [GO:0033674]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; sensory perception of sound [GO:0007605] GO:0001725; GO:0004714; GO:0005524; GO:0005737; GO:0005886; GO:0007605; GO:0009986; GO:0010976; GO:0014002; GO:0014068; GO:0017147; GO:0033674; GO:0042813; GO:0043123; GO:0043235; GO:0043679; GO:0048839; GO:0051092 10063 XM_029354241.2 13 1 1 5 71 NA NA NA NA NA NA 10064 XR_003822812.2 656 563 15 254 1 NA NA NA NA NA NA 10065 XM_029328478.2 464 257 205 235 356 Q53RE8 1.13e-48 Ankyrin repeat domain-containing protein 39 Homo sapiens (Human) protein K6-linked ubiquitination [GO:0085020] GO:0031436; GO:0070531; GO:0085020 10066 XM_029356997.2 53 14 14 198 1432 Q8C9W3 4.04e-97 A disintegrin and metalloproteinase with thrombospondin motifs 2 (ADAM-TS 2) (ADAM-TS2) (ADAMTS-2) (EC 3.4.24.14) (Procollagen I N-proteinase) (PC I-NP) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen N-endopeptidase) (pNPI) Mus musculus (Mouse) collagen catabolic process [GO:0030574]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; lung development [GO:0030324]; protein processing [GO:0016485]; skin development [GO:0043588]; spermatogenesis [GO:0007283] GO:0004222; GO:0005576; GO:0007283; GO:0008233; GO:0008270; GO:0016485; GO:0030198; GO:0030199; GO:0030324; GO:0030574; GO:0031012; GO:0043588; GO:0062023 10067 XM_029356997.2 53 14 14 198 1432 Q8C9W3 9.35e-43 A disintegrin and metalloproteinase with thrombospondin motifs 2 (ADAM-TS 2) (ADAM-TS2) (ADAMTS-2) (EC 3.4.24.14) (Procollagen I N-proteinase) (PC I-NP) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen N-endopeptidase) (pNPI) Mus musculus (Mouse) collagen catabolic process [GO:0030574]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; lung development [GO:0030324]; protein processing [GO:0016485]; skin development [GO:0043588]; spermatogenesis [GO:0007283] GO:0004222; GO:0005576; GO:0007283; GO:0008233; GO:0008270; GO:0016485; GO:0030198; GO:0030199; GO:0030324; GO:0030574; GO:0031012; GO:0043588; GO:0062023 10068 XM_029343981.2 0 0 196 0 340 B9EJ86 0 Oxysterol-binding protein-related protein 8 (ORP-8) (OSBP-related protein 8) Mus musculus (Mouse) activation of protein kinase B activity [GO:0032148]; fat cell differentiation [GO:0045444]; negative regulation of cell migration [GO:0030336]; negative regulation of sequestering of triglyceride [GO:0010891]; phospholipid transport [GO:0015914]; positive regulation of glucose import [GO:0046326]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of protein kinase B signaling [GO:0051897]; protein localization to nuclear pore [GO:0090204] GO:0001786; GO:0005783; GO:0005789; GO:0005829; GO:0010891; GO:0015248; GO:0015485; GO:0015914; GO:0016020; GO:0030336; GO:0031965; GO:0032148; GO:0032541; GO:0032934; GO:0043231; GO:0045444; GO:0046326; GO:0046628; GO:0051897; GO:0070273; GO:0090204; GO:0140343 10069 XM_029330092.2 36 162 49 41 35 NA NA NA NA NA NA 10070 XM_029344946.2 0 52 52 0 50 Q4G0X4 7.26e-32 BTB/POZ domain-containing protein KCTD21 (KCASH2 protein) (Potassium channel tetramerization domain-containing protein 21) Homo sapiens (Human) negative regulation of smoothened signaling pathway [GO:0045879]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0006511; GO:0016567; GO:0042802; GO:0042826; GO:0045879; GO:0051260; GO:0097602 10071 XM_044316374.1 908 929 1988 2251 1186 P98133 2.6e-170 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 10072 XM_044316374.1 908 929 1988 2251 1186 P98133 6.45e-168 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 10073 XM_044316374.1 908 929 1988 2251 1186 P98133 7.64e-130 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 10074 XM_044316374.1 908 929 1988 2251 1186 P98133 2.7e-126 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 10075 XM_044316374.1 908 929 1988 2251 1186 P98133 3.79e-96 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 10076 XM_044316374.1 908 929 1988 2251 1186 P98133 5.04e-92 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 10077 XM_044316374.1 908 929 1988 2251 1186 P98133 1.76e-64 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 10078 XM_044316374.1 908 929 1988 2251 1186 P98133 2.55e-41 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 10079 XM_044316374.1 908 929 1988 2251 1186 P98133 8.11e-31 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 10080 XM_044316374.1 908 929 1988 2251 1186 P98133 9.94e-30 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 10081 XM_044316374.1 908 929 1988 2251 1186 P98133 2.62e-24 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 10082 XM_044316374.1 908 929 1988 2251 1186 P98133 1.37e-23 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 10083 XR_003827813.2 37 35 46 40 69 NA NA NA NA NA NA 10084 XM_044312734.1 44 7 48 15 155 NA NA NA NA NA NA 10085 XM_044318944.1 603 263 230 134 317 P38935 0 DNA-binding protein SMUBP-2 (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent helicase IGHMBP2) (Glial factor 1) (GF-1) (Immunoglobulin mu-binding protein 2) Homo sapiens (Human) DNA duplex unwinding [GO:0032508]; RNA secondary structure unwinding [GO:0010501] GO:0000049; GO:0003677; GO:0003678; GO:0003697; GO:0003723; GO:0003727; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0008094; GO:0008134; GO:0008186; GO:0008270; GO:0010501; GO:0016020; GO:0016604; GO:0016887; GO:0030424; GO:0030426; GO:0032508; GO:0032574; GO:0036121; GO:0042802; GO:0043022; GO:0043139; GO:1990904 10086 XM_029356745.2 254 184 75 203 108 Q9Y4P3 4.83e-126 Transducin beta-like protein 2 (WS beta-transducin repeats protein) (WS-betaTRP) (Williams-Beuren syndrome chromosomal region 13 protein) Homo sapiens (Human) cellular response to glucose starvation [GO:0042149]; cellular response to hypoxia [GO:0071456]; endoplasmic reticulum unfolded protein response [GO:0030968] GO:0003723; GO:0005783; GO:0005789; GO:0019901; GO:0030968; GO:0031369; GO:0042149; GO:0051219; GO:0071456 10087 XR_006396631.1 91 15 27 55 0 NA NA NA NA NA NA 10088 XM_029346422.2 1439 916 669 804 267 P17706 8.72e-100 Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP) Homo sapiens (Human) B cell differentiation [GO:0030183]; erythrocyte differentiation [GO:0030218]; glucose homeostasis [GO:0042593]; insulin receptor recycling [GO:0038020]; insulin receptor signaling pathway [GO:0008286]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemotaxis [GO:0050922]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of inflammatory response [GO:0050728]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of interleukin-2-mediated signaling pathway [GO:1902206]; negative regulation of interleukin-4-mediated signaling pathway [GO:1902215]; negative regulation of interleukin-6-mediated signaling pathway [GO:0070104]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage colony-stimulating factor signaling pathway [GO:1902227]; negative regulation of macrophage differentiation [GO:0045650]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of positive thymic T cell selection [GO:1902233]; negative regulation of protein tyrosine kinase activity [GO:0061099]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; negative regulation of type II interferon-mediated signaling pathway [GO:0060336]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; peptidyl-tyrosine dephosphorylation [GO:0035335]; positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902237]; positive regulation of gluconeogenesis [GO:0045722]; positive regulation of PERK-mediated unfolded protein response [GO:1903899]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of type II interferon-mediated signaling pathway [GO:0060334]; T cell differentiation [GO:0030217] GO:0000122; GO:0004725; GO:0004726; GO:0005178; GO:0005634; GO:0005654; GO:0005737; GO:0005783; GO:0005793; GO:0005829; GO:0005886; GO:0008285; GO:0008286; GO:0010804; GO:0010888; GO:0019901; GO:0019905; GO:0030183; GO:0030217; GO:0030218; GO:0030971; GO:0031904; GO:0035335; GO:0038020; GO:0042059; GO:0042532; GO:0042593; GO:0045650; GO:0045722; GO:0046426; GO:0046627; GO:0050728; GO:0050860; GO:0050922; GO:0060334; GO:0060336; GO:0060339; GO:0061099; GO:0070104; GO:0070373; GO:0097677; GO:1902202; GO:1902206; GO:1902215; GO:1902227; GO:1902233; GO:1902237; GO:1903899; GO:2000587 10089 XM_044327053.1 0 25 18 0 124 NA NA NA NA NA NA 10090 XM_029357734.2 104 71 86 46 121 NA NA NA NA NA NA 10091 XM_029326346.2 17 0 36 5 74 NA NA NA NA NA NA 10092 XM_029358534.2 0 0 75 129 164 Q12830 2e-82 Nucleosome-remodeling factor subunit BPTF (Bromodomain and PHD finger-containing transcription factor) (Fetal Alz-50 clone 1 protein) (Fetal Alzheimer antigen) Homo sapiens (Human) anterior/posterior pattern specification [GO:0009952]; brain development [GO:0007420]; chromatin remodeling [GO:0006338]; embryonic placenta development [GO:0001892]; endoderm development [GO:0007492]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000785; GO:0000978; GO:0001892; GO:0005634; GO:0005654; GO:0005737; GO:0006338; GO:0006355; GO:0006357; GO:0007420; GO:0007492; GO:0009952; GO:0016589; GO:0035064; GO:0043565; GO:0045944; GO:0046872; GO:0070062; GO:1904949 10093 XM_029358534.2 0 0 75 129 164 Q12830 1.55e-63 Nucleosome-remodeling factor subunit BPTF (Bromodomain and PHD finger-containing transcription factor) (Fetal Alz-50 clone 1 protein) (Fetal Alzheimer antigen) Homo sapiens (Human) anterior/posterior pattern specification [GO:0009952]; brain development [GO:0007420]; chromatin remodeling [GO:0006338]; embryonic placenta development [GO:0001892]; endoderm development [GO:0007492]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000785; GO:0000978; GO:0001892; GO:0005634; GO:0005654; GO:0005737; GO:0006338; GO:0006355; GO:0006357; GO:0007420; GO:0007492; GO:0009952; GO:0016589; GO:0035064; GO:0043565; GO:0045944; GO:0046872; GO:0070062; GO:1904949 10094 XM_029358534.2 0 0 75 129 164 Q12830 1.33e-46 Nucleosome-remodeling factor subunit BPTF (Bromodomain and PHD finger-containing transcription factor) (Fetal Alz-50 clone 1 protein) (Fetal Alzheimer antigen) Homo sapiens (Human) anterior/posterior pattern specification [GO:0009952]; brain development [GO:0007420]; chromatin remodeling [GO:0006338]; embryonic placenta development [GO:0001892]; endoderm development [GO:0007492]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000785; GO:0000978; GO:0001892; GO:0005634; GO:0005654; GO:0005737; GO:0006338; GO:0006355; GO:0006357; GO:0007420; GO:0007492; GO:0009952; GO:0016589; GO:0035064; GO:0043565; GO:0045944; GO:0046872; GO:0070062; GO:1904949 10095 XM_029358534.2 0 0 75 129 164 Q12830 1.09e-24 Nucleosome-remodeling factor subunit BPTF (Bromodomain and PHD finger-containing transcription factor) (Fetal Alz-50 clone 1 protein) (Fetal Alzheimer antigen) Homo sapiens (Human) anterior/posterior pattern specification [GO:0009952]; brain development [GO:0007420]; chromatin remodeling [GO:0006338]; embryonic placenta development [GO:0001892]; endoderm development [GO:0007492]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000785; GO:0000978; GO:0001892; GO:0005634; GO:0005654; GO:0005737; GO:0006338; GO:0006355; GO:0006357; GO:0007420; GO:0007492; GO:0009952; GO:0016589; GO:0035064; GO:0043565; GO:0045944; GO:0046872; GO:0070062; GO:1904949 10096 XM_044325963.1 60 33 31 67 46 NA NA NA NA NA NA 10097 XM_029330216.2 0 0 0 0 21 A5D7U4 2.56e-49 Amiloride-sensitive sodium channel subunit beta (Beta-NaCH) (Epithelial Na(+) channel subunit beta) (Beta-ENaC) (Nonvoltage-gated sodium channel 1 subunit beta) (SCNEB) Bos taurus (Bovine) aldosterone metabolic process [GO:0032341]; artery smooth muscle contraction [GO:0014824]; cellular response to acidic pH [GO:0071468]; cellular response to aldosterone [GO:1904045]; cellular response to amiloride [GO:0036254]; cellular sodium ion homeostasis [GO:0006883]; epithelial fluid transport [GO:0042045]; erythrocyte homeostasis [GO:0034101]; gene expression [GO:0010467]; leukocyte activation involved in inflammatory response [GO:0002269]; mucus secretion [GO:0070254]; multicellular organism growth [GO:0035264]; multicellular organismal water homeostasis [GO:0050891]; neutrophil activation involved in immune response [GO:0002283]; neutrophil-mediated killing of bacterium [GO:0070944]; potassium ion homeostasis [GO:0055075]; response to food [GO:0032094]; response to xenobiotic stimulus [GO:0009410]; sensory perception of taste [GO:0050909]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725]; urea homeostasis [GO:0097274] GO:0002269; GO:0002283; GO:0005886; GO:0006883; GO:0009410; GO:0009897; GO:0010467; GO:0014824; GO:0015280; GO:0016324; GO:0030659; GO:0032094; GO:0032341; GO:0034101; GO:0034706; GO:0035264; GO:0035725; GO:0036254; GO:0042045; GO:0050699; GO:0050891; GO:0050909; GO:0055075; GO:0070062; GO:0070254; GO:0070944; GO:0071468; GO:0097274; GO:0098719; GO:1904045 10098 XR_006397767.1 9 0 0 68 25 NA NA NA NA NA NA 10099 XR_006392749.1 10 8 4 0 17 NA NA NA NA NA NA 10100 XR_006394033.1 69 5 22 25 14 NA NA NA NA NA NA 10101 XM_044319216.1 179 108 85 203 238 P0DX22 2.82e-54 NA NA NA NA 10102 XR_006393216.1 117 79 89 113 62 NA NA NA NA NA NA 10103 XM_044324703.1 11 43 67 11 5 Q05609 3.59e-24 Serine/threonine-protein kinase CTR1 (EC 2.7.11.1) (Protein CONSTITUTIVE TRIPLE RESPONSE1) Arabidopsis thaliana (Mouse-ear cress) ethylene-activated signaling pathway [GO:0009873]; gibberellin biosynthetic process [GO:0009686]; negative regulation of ethylene-activated signaling pathway [GO:0010105]; protein autophosphorylation [GO:0046777]; regulation of post-embryonic root development [GO:2000069]; regulation of stem cell division [GO:2000035]; regulation of timing of transition from vegetative to reproductive phase [GO:0048510]; response to ethylene [GO:0009723]; response to fructose [GO:0009750]; response to hypoxia [GO:0001666]; response to sucrose [GO:0009744]; sugar mediated signaling pathway [GO:0010182] GO:0001666; GO:0004674; GO:0004712; GO:0005524; GO:0005789; GO:0009686; GO:0009723; GO:0009744; GO:0009750; GO:0009873; GO:0010105; GO:0010182; GO:0046777; GO:0048510; GO:0106310; GO:2000035; GO:2000069 10104 XM_044319238.1 72 0 4 597 23 NA NA NA NA NA NA 10105 XM_044320420.1 211 116 79 28 230 NA NA NA NA NA NA 10106 XM_044316876.1 6 0 6 0 23 Q9JM13 2.48e-69 Rab5 GDP/GTP exchange factor (Rabex-5) Mus musculus (Mouse) dendritic transport [GO:0098935]; establishment of localization in cell [GO:0051649]; Kit signaling pathway [GO:0038109]; mast cell degranulation [GO:0043303]; mast cell migration [GO:0097531]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of Kit signaling pathway [GO:1900235]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of mast cell activation [GO:0033004]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; negative regulation of receptor-mediated endocytosis [GO:0048261]; protein phosphorylation [GO:0006468]; protein targeting to membrane [GO:0006612]; Ras protein signal transduction [GO:0007265]; receptor-mediated endocytosis [GO:0006898]; regulation of Fc receptor mediated stimulatory signaling pathway [GO:0060368] GO:0001933; GO:0002686; GO:0003677; GO:0005085; GO:0005730; GO:0005769; GO:0005829; GO:0006468; GO:0006612; GO:0006898; GO:0007265; GO:0008270; GO:0030139; GO:0030425; GO:0031267; GO:0031982; GO:0032715; GO:0032764; GO:0033004; GO:0038109; GO:0043303; GO:0043305; GO:0046580; GO:0048261; GO:0050728; GO:0051649; GO:0055037; GO:0060368; GO:0061630; GO:0097531; GO:0098935; GO:1900235 10107 XM_044327320.1 363 208 275 438 650 NA NA NA NA NA NA 10108 XR_006397294.1 102 197 115 124 150 NA NA NA NA NA NA 10109 XM_029327073.2 240 238 128 180 123 NA NA NA NA NA NA 10110 XM_029327072.2 654 557 526 840 1150 Q9UJZ1 1.01e-137 Stomatin-like protein 2, mitochondrial (SLP-2) (EPB72-like protein 2) (Paraprotein target 7) (Paratarg-7) Homo sapiens (Human) CD4-positive, alpha-beta T cell activation [GO:0035710]; cellular calcium ion homeostasis [GO:0006874]; lipid localization [GO:0010876]; mitochondrial protein processing [GO:0034982]; mitochondrion organization [GO:0007005]; positive regulation of interleukin-2 production [GO:0032743]; protein complex oligomerization [GO:0051259]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776]; stress-induced mitochondrial fusion [GO:1990046]; T cell receptor signaling pathway [GO:0050852] GO:0001772; GO:0005739; GO:0005743; GO:0005758; GO:0005886; GO:0006874; GO:0007005; GO:0010876; GO:0015629; GO:0032743; GO:0034982; GO:0035710; GO:0042608; GO:0042776; GO:0045121; GO:0050852; GO:0051020; GO:0051259; GO:1901612; GO:1990046 10111 XM_044328310.1 19 0 0 13 0 NA NA NA NA NA NA 10112 XM_044314948.1 0 0 0 12 1 NA NA NA NA NA NA 10113 XM_044309293.1 129 21 64 100 29 NA NA NA NA NA NA 10114 XM_029348828.2 1457 1817 1131 1099 1571 Q5M8F7 1.23e-39 Nuclear envelope phosphatase-regulatory subunit 1 (Transmembrane protein 188) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) lipid metabolic process [GO:0006629]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of triglyceride biosynthetic process [GO:0010867] GO:0005737; GO:0006629; GO:0010867; GO:0031965; GO:0035307; GO:0071595 10115 XR_006391968.1 0 12 3 12 1 NA NA NA NA NA NA 10116 XM_044317246.1 1017 322 196 160 101 NA NA NA NA NA NA 10117 XM_029345044.2 812 353 28 470 459 NA NA NA NA NA NA 10118 XR_006395007.1 97 47 73 18 222 NA NA NA NA NA NA 10119 XM_029347515.2 67 65 42 90 69 Q1ZZH1 1.55e-109 Metabotropic glutamate receptor 3 (mGluR3) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0004930; GO:0005886; GO:0008066 10120 XM_044322606.1 21 2 23 23 1 NA NA NA NA NA NA 10121 XR_006396230.1 72 128 46 95 40 Q6ZSS7 9.64e-66 Major facilitator superfamily domain-containing protein 6 (Macrophage MHC class I receptor 2 homolog) Homo sapiens (Human) antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590] GO:0005886; GO:0016020; GO:0042590 10122 XM_029345027.2 0 13 9 54 34 P56730 1.67e-41 Neurotrypsin (EC 3.4.21.-) (Leydin) (Motopsin) (Serine protease 12) Homo sapiens (Human) exocytosis [GO:0006887]; zymogen activation [GO:0031638] GO:0004252; GO:0005044; GO:0005886; GO:0006887; GO:0008236; GO:0030424; GO:0030425; GO:0031410; GO:0031638; GO:0043083; GO:0043195 10123 XM_029345027.2 0 13 9 54 34 P56730 4e-29 Neurotrypsin (EC 3.4.21.-) (Leydin) (Motopsin) (Serine protease 12) Homo sapiens (Human) exocytosis [GO:0006887]; zymogen activation [GO:0031638] GO:0004252; GO:0005044; GO:0005886; GO:0006887; GO:0008236; GO:0030424; GO:0030425; GO:0031410; GO:0031638; GO:0043083; GO:0043195 10124 XM_044317028.1 202 148 150 267 332 NA NA NA NA NA NA 10125 XM_029338540.2 0 74 239 315 139 Q9DDT2 3.69e-22 Phosphoinositide 3-kinase adapter protein 1 (B-cell adapter for phosphoinositide 3-kinase) (B-cell phosphoinositide 3-kinase adapter protein 1) Gallus gallus (Chicken) cellular response to insulin stimulus [GO:0032869]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; regulation of inflammatory response [GO:0050727]; regulation of kinase activity [GO:0043549]; regulation of phosphorylation [GO:0042325]; toll-like receptor 2 signaling pathway [GO:0034134]; toll-like receptor 4 signaling pathway [GO:0034142]; toll-like receptor 7 signaling pathway [GO:0034154]; toll-like receptor 9 signaling pathway [GO:0034162]; TOR signaling [GO:0031929] GO:0005102; GO:0005829; GO:0005886; GO:0014068; GO:0016020; GO:0031929; GO:0032869; GO:0034134; GO:0034142; GO:0034154; GO:0034162; GO:0036312; GO:0042325; GO:0043549; GO:0050727 10126 XM_044310243.1 12 4 0 0 0 Q5F371 1.28e-52 Protein strawberry notch homolog 1 Gallus gallus (Chicken) regulation of DNA-templated transcription [GO:0006355]; regulation of response to stimulus [GO:0048583] GO:0005634; GO:0006355; GO:0031490; GO:0042393; GO:0048583 10127 XM_044310243.1 12 4 0 0 0 Q5F371 1.28e-52 Protein strawberry notch homolog 1 Gallus gallus (Chicken) regulation of DNA-templated transcription [GO:0006355]; regulation of response to stimulus [GO:0048583] GO:0005634; GO:0006355; GO:0031490; GO:0042393; GO:0048583 10128 XM_044326870.1 324 625 506 756 768 NA NA NA NA NA NA 10129 XM_044318518.1 10 5 25 0 18 NA NA NA NA NA NA 10130 XM_029328685.2 0 78 75 0 0 NA NA NA NA NA NA 10131 XR_006397287.1 4 8 4 9 15 NA NA NA NA NA NA 10132 XM_044314134.1 0 0 0 0 31 NA NA NA NA NA NA 10133 XR_006394858.1 105 75 105 158 200 NA NA NA NA NA NA 10134 XM_044323491.1 1 37 0 0 40 Q96AY4 8.08e-115 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10135 XM_044323491.1 1 37 0 0 40 Q96AY4 4.29e-112 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10136 XM_044323491.1 1 37 0 0 40 Q96AY4 1.68e-96 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10137 XM_044323491.1 1 37 0 0 40 Q96AY4 2.47e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10138 XM_044323491.1 1 37 0 0 40 Q96AY4 3.81e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10139 XM_029342263.2 1271 1141 647 652 756 O00712 9.95e-96 Nuclear factor 1 B-type (NF1-B) (Nuclear factor 1/B) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/B) (NF-I/B) (NFI-B) (TGGCA-binding protein) Homo sapiens (Human) anterior commissure morphogenesis [GO:0021960]; brain development [GO:0007420]; cell differentiation involved in salivary gland development [GO:0060689]; chondrocyte differentiation [GO:0002062]; club cell differentiation [GO:0060486]; commissural neuron axon guidance [GO:0071679]; DNA replication [GO:0006260]; glandular epithelial cell differentiation [GO:0002067]; glial cell differentiation [GO:0010001]; hindbrain development [GO:0030902]; lung ciliated cell differentiation [GO:0061141]; negative regulation of DNA binding [GO:0043392]; negative regulation of epithelial cell proliferation involved in lung morphogenesis [GO:2000795]; negative regulation of mesenchymal cell proliferation involved in lung development [GO:2000791]; negative regulation of miRNA transcription [GO:1902894]; negative regulation of stem cell proliferation [GO:2000647]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; principal sensory nucleus of trigeminal nerve development [GO:0021740]; regulation of transcription by RNA polymerase II [GO:0006357]; response to bacterium [GO:0009617]; salivary gland cavitation [GO:0060662]; stem cell proliferation [GO:0072089]; type I pneumocyte differentiation [GO:0060509]; type II pneumocyte differentiation [GO:0060510] GO:0000122; GO:0000785; GO:0000978; GO:0000981; GO:0001228; GO:0001650; GO:0002062; GO:0002067; GO:0003677; GO:0005634; GO:0005654; GO:0006260; GO:0006357; GO:0007420; GO:0009617; GO:0010001; GO:0021740; GO:0021960; GO:0030902; GO:0043392; GO:0044300; GO:0045893; GO:0045944; GO:0060486; GO:0060509; GO:0060510; GO:0060662; GO:0060689; GO:0061141; GO:0071679; GO:0072089; GO:0140416; GO:1902894; GO:1990837; GO:2000647; GO:2000791; GO:2000795 10140 XM_029339779.2 1772 1821 1287 2739 2737 NA NA NA NA NA NA 10141 XM_044317933.1 2191 695 1044 1475 877 Q54TR1 6.42e-90 Counting factor associated protein D Dictyostelium discoideum (Social amoeba) immune response [GO:0006955]; negative regulation of asexual reproduction [GO:1903665]; positive regulation of chemorepellent activity [GO:1903669]; protein localization to plasma membrane [GO:0072659]; proteolysis involved in protein catabolic process [GO:0051603]; sorocarp morphogenesis [GO:0031288] GO:0004197; GO:0005576; GO:0005615; GO:0005764; GO:0006955; GO:0031288; GO:0031410; GO:0051603; GO:0072659; GO:1903665; GO:1903669 10142 XM_029339090.2 6 93 25 41 11 Q9CYL5 6.94e-39 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Mus musculus (Mouse) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070374 10143 XM_029339090.2 6 93 25 41 11 Q9CYL5 5.56e-35 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Mus musculus (Mouse) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070374 10144 XM_029341135.2 187 171 86 191 219 Q6IQ20 4.63e-125 N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D (N-acyl phosphatidylethanolamine phospholipase D) (NAPE-PLD) (NAPE-hydrolyzing phospholipase D) (EC 3.1.4.54) Homo sapiens (Human) host-mediated regulation of intestinal microbiota composition [GO:0048874]; N-acylethanolamine metabolic process [GO:0070291]; N-acylphosphatidylethanolamine metabolic process [GO:0070292]; phospholipid catabolic process [GO:0009395]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of inflammatory response [GO:0050729]; retinoid metabolic process [GO:0001523]; temperature homeostasis [GO:0001659] GO:0000139; GO:0001523; GO:0001659; GO:0005635; GO:0005654; GO:0005737; GO:0005769; GO:0005794; GO:0008270; GO:0009395; GO:0031901; GO:0032052; GO:0042622; GO:0042802; GO:0043227; GO:0048874; GO:0050729; GO:0070062; GO:0070290; GO:0070291; GO:0070292; GO:0090336; GO:0102200 10145 XM_044318452.1 1041 454 722 755 1193 Q964E3 0 Actin, cytoplasmic (EC 3.6.4.-) [Cleaved into: Actin, cytoplasmic, intermediate form] Biomphalaria alexandrina (Bloodfluke planorb) (Freshwater snail) NA GO:0005524; GO:0005737; GO:0005856; GO:0016787 10146 XM_044318452.1 1041 454 722 755 1193 Q964E3 5.56e-103 Actin, cytoplasmic (EC 3.6.4.-) [Cleaved into: Actin, cytoplasmic, intermediate form] Biomphalaria alexandrina (Bloodfluke planorb) (Freshwater snail) NA GO:0005524; GO:0005737; GO:0005856; GO:0016787 10147 XM_029336749.2 0 0 0 59 56 Q6UWE0 8.41e-138 E3 ubiquitin-protein ligase LRSAM1 (EC 2.3.2.27) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (RING-type E3 ubiquitin transferase LRSAM1) (Tsg101-associated ligase) (hTAL) Homo sapiens (Human) autophagy [GO:0006914]; negative regulation of endocytosis [GO:0045806]; positive regulation of autophagosome assembly [GO:2000786]; positive regulation of xenophagy [GO:1904417]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein polyubiquitination [GO:0000209]; ubiquitin-dependent endocytosis [GO:0070086]; viral budding [GO:0046755] GO:0000209; GO:0004842; GO:0005737; GO:0005829; GO:0006914; GO:0016020; GO:0030163; GO:0045806; GO:0046755; GO:0046872; GO:0051865; GO:0061630; GO:0070086; GO:1904417; GO:2000786 10148 XM_044325356.1 3 0 1 0 33 P48733 5.27e-30 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Bos taurus (Bovine) antibacterial innate immune response [GO:0140367]; defense response to Gram-negative bacterium [GO:0050829] GO:0000922; GO:0005201; GO:0005509; GO:0005576; GO:0005929; GO:0016020; GO:0016323; GO:0016324; GO:0031012; GO:0050829; GO:0060170; GO:0140367 10149 XM_044329266.1 4 348 19 7 661 NA NA NA NA NA NA 10150 XR_003823650.2 2 8 9 0 52 NA NA NA NA NA NA 10151 XM_029353097.2 28 18 2 14 113 Q96MB7 1.64e-44 Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease) Homo sapiens (Human) NA GO:0004518; GO:0005634; GO:0005829; GO:0005886; GO:0034451; GO:0046872 10152 XM_029353097.2 28 18 2 14 113 Q96MB7 1.64e-44 Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease) Homo sapiens (Human) NA GO:0004518; GO:0005634; GO:0005829; GO:0005886; GO:0034451; GO:0046872 10153 XR_006394900.1 2 0 1 7 16 NA NA NA NA NA NA 10154 XM_044323068.1 8 2 11 0 0 NA NA NA NA NA NA 10155 XM_044325842.1 0 0 154 261 203 NA NA NA NA NA NA 10156 XR_006395208.1 1 27 0 107 0 NA NA NA NA NA NA 10157 XR_006396339.1 60 0 101 0 88 NA NA NA NA NA NA 10158 XM_029340817.2 79 369 369 236 235 Q8K3C3 1.3e-66 Protein LZIC (Leucine zipper and CTNNBIP1 domain-containing protein) (Leucine zipper and ICAT homologous domain-containing protein) Mus musculus (Mouse) negative regulation of Wnt signaling pathway [GO:0030178] GO:0008013; GO:0030178 10159 XM_044328637.1 6 9 13 9 27 A0JC51 1.27e-81 Zinc finger protein ZIC 4 (XlZic4) (Zinc finger protein of the cerebellum 4) Xenopus laevis (African clawed frog) nervous system development [GO:0007399]; neural crest formation [GO:0014029] GO:0003677; GO:0005634; GO:0007399; GO:0014029; GO:0046872 10160 XM_029348955.2 4480 3956 2968 3850 2280 Q96DB2 3.51e-144 Histone deacetylase 11 (HD11) (EC 3.5.1.98) Homo sapiens (Human) chromatin organization [GO:0006325]; histone deacetylation [GO:0016575]; oligodendrocyte development [GO:0014003] GO:0000118; GO:0004407; GO:0005634; GO:0005886; GO:0006325; GO:0014003; GO:0016575; GO:0140297 10161 XM_029337885.2 251 33 96 38 301 NA NA NA NA NA NA 10162 XM_044313544.1 46 46 65 48 44 NA NA NA NA NA NA 10163 XR_006391585.1 63 31 22 0 52 NA NA NA NA NA NA 10164 XM_029346442.2 0 29 0 60 203 NA NA NA NA NA NA 10165 XM_029357444.2 28 69 101 44 13 O43196 0 MutS protein homolog 5 (hMSH5) Homo sapiens (Human) chiasma assembly [GO:0051026]; mismatch repair [GO:0006298] GO:0003690; GO:0005524; GO:0005634; GO:0006298; GO:0030983; GO:0051026; GO:0140664 10166 XR_006394048.1 394 65 231 274 388 NA NA NA NA NA NA 10167 XR_006393980.1 3 8 0 0 0 NA NA NA NA NA NA 10168 XM_029358634.2 0 9 27 16 21 Q9GZQ4 1.03e-21 Neuromedin-U receptor 2 (NMU-R2) (G-protein coupled receptor FM-4) (G-protein coupled receptor TGR-1) Homo sapiens (Human) arachidonic acid secretion [GO:0050482]; calcium ion transport [GO:0006816]; calcium-mediated signaling [GO:0019722]; cell-cell signaling [GO:0007267]; central nervous system development [GO:0007417]; feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; grooming behavior [GO:0007625]; inositol phosphate-mediated signaling [GO:0048016]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; reduction of food intake in response to dietary excess [GO:0002023]; regulation of sensory perception of pain [GO:0051930]; regulation of smooth muscle contraction [GO:0006940]; response to pain [GO:0048265] GO:0001607; GO:0002023; GO:0004930; GO:0005229; GO:0005525; GO:0005886; GO:0006816; GO:0006940; GO:0007186; GO:0007200; GO:0007204; GO:0007218; GO:0007267; GO:0007417; GO:0007625; GO:0007631; GO:0008188; GO:0016020; GO:0019722; GO:0042924; GO:0048016; GO:0048265; GO:0050482; GO:0051930 10169 XR_006391658.1 339 159 156 232 205 NA NA NA NA NA NA 10170 XM_029350638.2 883 1255 593 839 561 NA NA NA NA NA NA 10171 XM_029341181.2 0 42 0 0 13 Q91175 1.12e-42 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (MAR1) Oryzias latipes (Japanese rice fish) (Japanese killifish) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of vasoconstriction [GO:0045907] GO:0001996; GO:0004930; GO:0004937; GO:0005886; GO:0007200; GO:0007204; GO:0007267; GO:0043410; GO:0045907; GO:0071880 10172 XM_029348902.2 3067 1432 1520 2819 2714 O16025 0 Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (AOS) (EC 4.2.1.-) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)] Plexaura homomalla (Black sea rod) arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; lipid oxidation [GO:0034440]; oxylipin biosynthetic process [GO:0031408] GO:0005506; GO:0005737; GO:0006633; GO:0009978; GO:0016020; GO:0019369; GO:0020037; GO:0031408; GO:0034440; GO:0047677 10173 XR_006397490.1 4 0 0 4 18 NA NA NA NA NA NA 10174 XM_029353245.2 1418 1430 739 1016 478 NA NA NA NA NA NA 10175 XM_029354786.2 6 1 4 0 0 NA NA NA NA NA NA 10176 XM_029337300.2 26 25 40 82 58 Q8K2H6 2.98e-84 Anaphase-promoting complex subunit 10 (APC10) (Cyclosome subunit 10) Mus musculus (Mouse) anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell cycle [GO:0007049]; cell division [GO:0051301]; protein K11-linked ubiquitination [GO:0070979] GO:0005680; GO:0005737; GO:0007049; GO:0031145; GO:0051301; GO:0070979 10177 XR_006394777.1 1 0 1 0 10 NA NA NA NA NA NA 10178 XM_044309958.1 220 14 111 276 119 NA NA NA NA NA NA 10179 XR_006391939.1 70 29 73 28 93 NA NA NA NA NA NA 10180 XR_006391755.1 23 0 0 39 17 NA NA NA NA NA NA 10181 XM_044313976.1 0 1 3 0 6 NA NA NA NA NA NA 10182 XM_044318493.1 0 7 0 0 0 NA NA NA NA NA NA 10183 XR_003826792.2 18 3 5 6 25 NA NA NA NA NA NA 10184 XM_044321218.1 71 46 69 149 134 A6H603 6.33e-108 NACHT domain- and WD repeat-containing protein 1 Mus musculus (Mouse) negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of gene expression [GO:0010628] GO:0005524; GO:0005730; GO:0005829; GO:0010628; GO:0032088 10185 XM_044321765.1 0 44 28 73 26 Q91740 9.73e-22 Fibronectin (FN) Xenopus laevis (African clawed frog) acute-phase response [GO:0006953]; cell adhesion [GO:0007155]; regulation of cell shape [GO:0008360] GO:0005576; GO:0006953; GO:0007155; GO:0008201; GO:0008360 10186 XM_029331037.2 3658 2900 2282 6012 2299 Q6Q2B2 5.64e-60 Muscleblind-like protein 2a (Tmbnl2a) Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0003723; GO:0005634; GO:0005737; GO:0006397; GO:0008380; GO:0046872 10187 XM_044315366.1 11 0 0 0 0 NA NA NA NA NA NA 10188 XM_044329207.1 0 18 20 0 42 NA NA NA NA NA NA 10189 XM_029323623.2 112 20 0 56 39 NA NA NA NA NA NA 10190 XM_029334437.2 0 0 0 7 0 NA NA NA NA NA NA 10191 XM_029339186.2 268 17 198 341 356 NA NA NA NA NA NA 10192 XR_006392763.1 161 51 99 126 220 NA NA NA NA NA NA 10193 XM_029323870.2 0 0 0 0 25 NA NA NA NA NA NA 10194 XM_044326973.1 0 0 0 0 11 NA NA NA NA NA NA 10195 XM_029339429.2 0 14 0 159 80 Q7T163 0 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 10196 XM_029339429.2 0 14 0 159 80 Q7T163 3.18e-42 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 10197 XM_029339429.2 0 14 0 159 80 Q7T163 3.04e-33 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 10198 XM_029339429.2 0 14 0 159 80 Q7T163 1.83e-29 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 10199 XM_029339429.2 0 14 0 159 80 Q7T163 4.81e-27 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 10200 XM_029339429.2 0 14 0 159 80 Q7T163 9.88e-23 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 10201 XM_029356000.2 1957 1070 996 1867 1880 A2AWA9 0 Rab GTPase-activating protein 1 (GAP and centrosome-associated protein) (Rab6 GTPase-activating protein GAPCenA) Mus musculus (Mouse) activation of GTPase activity [GO:0090630]; cell cycle [GO:0007049]; regulation of GTPase activity [GO:0043087] GO:0005096; GO:0005815; GO:0005829; GO:0007049; GO:0031267; GO:0043087; GO:0090630 10202 XM_044317880.1 194 112 116 262 261 NA NA NA NA NA NA 10203 XM_029326403.2 15 14 9 11 14 NA NA NA NA NA NA 10204 XM_029336448.2 0 0 0 55 0 NA NA NA NA NA NA 10205 XM_029333321.2 386 188 218 299 192 Q12923 2.91e-57 Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1) (PTP-BAS) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (Protein-tyrosine phosphatase PTPL1) Homo sapiens (Human) cellular response to toxic substance [GO:0097237]; negative regulation of excitatory synapse assembly [GO:1904890]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066] GO:0001650; GO:0001933; GO:0004725; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0006470; GO:0014066; GO:0030027; GO:0035335; GO:0036312; GO:0043005; GO:0044297; GO:0070062; GO:0097237; GO:1904890 10206 XM_029333321.2 386 188 218 299 192 Q12923 1.77e-28 Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1) (PTP-BAS) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (Protein-tyrosine phosphatase PTPL1) Homo sapiens (Human) cellular response to toxic substance [GO:0097237]; negative regulation of excitatory synapse assembly [GO:1904890]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066] GO:0001650; GO:0001933; GO:0004725; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0006470; GO:0014066; GO:0030027; GO:0035335; GO:0036312; GO:0043005; GO:0044297; GO:0070062; GO:0097237; GO:1904890 10207 XM_044325462.1 3 641 0 0 2 Q3SZ45 3.92e-79 Stromal cell-derived factor 2 (SDF-2) Bos taurus (Bovine) NA GO:0005576 10208 XM_044308696.1 280 408 215 179 286 NA NA NA NA NA NA 10209 XM_044309465.1 1027 854 677 1382 1488 Q9JKL7 3.73e-38 Splicing regulatory glutamine/lysine-rich protein 1 (SR-related protein of 86 kDa) (Serine/arginine-rich-splicing regulatory protein 86) (SRrp86) (Splicing factor, arginine/serine-rich 12) Rattus norvegicus (Rat) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0003723; GO:0005654; GO:0005681; GO:0006397; GO:0008380 10210 XM_044322505.1 0 0 14 18 32 NA NA NA NA NA NA 10211 XM_029346972.2 0 38 0 30 0 Q6R520 6.9e-50 Calmodulin (CaM) Oreochromis mossambicus (Mozambique tilapia) (Tilapia mossambica) NA GO:0005509 10212 XM_029341587.2 0 0 37 208 31 A2AJN7 8.72e-177 Solute carrier family 4 member 11 (Sodium borate cotransporter 1) (NaBC1) Mus musculus (Mouse) bicarbonate transport [GO:0015701]; borate transport [GO:0046713]; cellular cation homeostasis [GO:0030003]; cellular hypotonic response [GO:0071476]; cellular response to oxidative stress [GO:0034599]; fluid transport [GO:0042044]; ion homeostasis [GO:0050801]; proton transmembrane transport [GO:1902600]; regulation of mesenchymal stem cell differentiation [GO:2000739]; regulation of mitochondrial membrane potential [GO:0051881]; sodium ion transport [GO:0006814]; transmembrane transport [GO:0055085] GO:0005272; GO:0005372; GO:0005452; GO:0005886; GO:0006814; GO:0012506; GO:0015078; GO:0015106; GO:0015252; GO:0015293; GO:0015701; GO:0016323; GO:0016324; GO:0022857; GO:0030003; GO:0034599; GO:0042044; GO:0046713; GO:0046715; GO:0046983; GO:0050801; GO:0051881; GO:0055085; GO:0071476; GO:1902600; GO:2000739 10213 XM_029337968.2 6344 5120 3446 4010 5253 O00339 1.3e-49 Matrilin-2 Homo sapiens (Human) extracellular matrix organization [GO:0030198] GO:0005201; GO:0005509; GO:0005576; GO:0030198; GO:0031012; GO:0062023; GO:0120216 10214 XM_029337968.2 6344 5120 3446 4010 5253 O00339 8.78e-40 Matrilin-2 Homo sapiens (Human) extracellular matrix organization [GO:0030198] GO:0005201; GO:0005509; GO:0005576; GO:0030198; GO:0031012; GO:0062023; GO:0120216 10215 XM_029337968.2 6344 5120 3446 4010 5253 O00339 7.63e-31 Matrilin-2 Homo sapiens (Human) extracellular matrix organization [GO:0030198] GO:0005201; GO:0005509; GO:0005576; GO:0030198; GO:0031012; GO:0062023; GO:0120216 10216 XM_029337968.2 6344 5120 3446 4010 5253 O00339 1.23e-30 Matrilin-2 Homo sapiens (Human) extracellular matrix organization [GO:0030198] GO:0005201; GO:0005509; GO:0005576; GO:0030198; GO:0031012; GO:0062023; GO:0120216 10217 XM_029337968.2 6344 5120 3446 4010 5253 O00339 3.55e-30 Matrilin-2 Homo sapiens (Human) extracellular matrix organization [GO:0030198] GO:0005201; GO:0005509; GO:0005576; GO:0030198; GO:0031012; GO:0062023; GO:0120216 10218 XM_029337968.2 6344 5120 3446 4010 5253 O00339 2.86e-22 Matrilin-2 Homo sapiens (Human) extracellular matrix organization [GO:0030198] GO:0005201; GO:0005509; GO:0005576; GO:0030198; GO:0031012; GO:0062023; GO:0120216 10219 XR_003825656.2 15 28 17 136 26 NA NA NA NA NA NA 10220 XM_044320695.1 0 0 5 1 8 NA NA NA NA NA NA 10221 XR_006398175.1 42 34 22 40 82 NA NA NA NA NA NA 10222 XR_006393494.1 47 88 59 114 107 NA NA NA NA NA NA 10223 XM_029335718.2 0 0 0 2 24 E7F7V7 4.99e-22 Galanin receptor 2b Danio rerio (Zebrafish) (Brachydanio rerio) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; neuropeptide signaling pathway [GO:0007218] GO:0004966; GO:0005886; GO:0007188; GO:0007218; GO:0008528 10224 XM_029356462.2 0 76 0 0 83 Q6DG32 9.16e-90 Solute carrier family 25 member 36-A Danio rerio (Zebrafish) (Brachydanio rerio) mitochondrial genome maintenance [GO:0000002]; pyrimidine nucleotide import into mitochondrion [GO:1990519] GO:0000002; GO:0005739; GO:0005743; GO:0015218; GO:1990519 10225 XM_029342403.2 353 272 169 402 348 Q0P4P2 2.48e-67 Fibrinogen C domain-containing protein 1 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0008061; GO:0016020; GO:0046872 10226 XM_044309810.1 0 0 35 0 141 P49013 8.24e-42 Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374 10227 XM_044309810.1 0 0 35 0 141 P49013 6.51e-40 Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374 10228 XM_044309810.1 0 0 35 0 141 P49013 4.92e-39 Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374 10229 XM_044309810.1 0 0 35 0 141 P49013 1.38e-36 Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374 10230 XM_044309810.1 0 0 35 0 141 P49013 2.07e-27 Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374 10231 XM_044309810.1 0 0 35 0 141 P49013 2.32e-26 Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374 10232 XR_006394872.1 66 96 11 89 63 NA NA NA NA NA NA 10233 XM_029329327.2 527 308 293 632 203 Q4R8N2 0 Protein lin-9 homolog Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) cell cycle [GO:0007049]; DNA biosynthetic process [GO:0071897]; DNA-templated transcription [GO:0006351] GO:0005654; GO:0006351; GO:0007049; GO:0017053; GO:0071897 10234 XR_003825665.2 380 459 188 1000 677 NA NA NA NA NA NA 10235 XR_006398135.1 0 10 0 0 0 NA NA NA NA NA NA 10236 XM_044322402.1 185 118 19 91 84 Q8VDU0 8.05e-28 G-protein-signaling modulator 2 (Pins homolog) Mus musculus (Mouse) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 10237 XM_044322402.1 185 118 19 91 84 Q8VDU0 2.02e-23 G-protein-signaling modulator 2 (Pins homolog) Mus musculus (Mouse) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 10238 XM_044320049.1 0 0 3 9 6 NA NA NA NA NA NA 10239 XM_029338966.2 0 0 0 71 0 Q7XJJ7 1.89e-93 Fatty acid amide hydrolase (AtFAAH) (EC 3.5.1.99) (N-acylethanolamine amidohydrolase) Arabidopsis thaliana (Mouse-ear cress) defense response to bacterium [GO:0042742]; lipid catabolic process [GO:0016042]; N-acylethanolamine metabolic process [GO:0070291] GO:0000325; GO:0005783; GO:0005789; GO:0005794; GO:0005886; GO:0009536; GO:0016020; GO:0016042; GO:0017064; GO:0042742; GO:0047412; GO:0070291 10240 XM_029339639.2 296 175 141 207 224 Q5ZLL8 6.77e-155 Glycerol-3-phosphate acyltransferase 3 (GPAT-3) (EC 2.3.1.15) (1-acyl-sn-glycerol-3-phosphate O-acyltransferase 10) (AGPAT 10) (1-acyl-sn-glycerol-3-phosphate O-acyltransferase 9) (1-AGP acyltransferase 9) (1-AGPAT 9) (EC 2.3.1.51) (Lysophosphatidic acid acyltransferase theta) (LPAAT-theta) Gallus gallus (Chicken) CDP-diacylglycerol biosynthetic process [GO:0016024]; triglyceride biosynthetic process [GO:0019432] GO:0003841; GO:0004366; GO:0005783; GO:0005789; GO:0016024; GO:0019432; GO:0102420 10241 XM_029335655.2 32285 41959 21946 31233 21602 P02362 1.73e-96 40S ribosomal protein S7 (40S ribosomal protein S8) Xenopus laevis (African clawed frog) translation [GO:0006412] GO:0003735; GO:0005840; GO:0006412; GO:1990904 10242 XM_044315891.1 29 0 3 37 14 NA NA NA NA NA NA 10243 XR_006394170.1 0 0 15 0 0 NA NA NA NA NA NA 10244 XR_003826584.2 9 1 14 3 72 NA NA NA NA NA NA 10245 XM_029338484.2 209 79 119 307 201 Q9VCA2 2.98e-100 Organic cation transporter protein Drosophila melanogaster (Fruit fly) apoptotic process [GO:0006915]; ion transport [GO:0006811] GO:0006811; GO:0006915; GO:0016020; GO:0022857 10246 XM_044315051.1 29 10 9 4 0 NA NA NA NA NA NA 10247 XR_006393044.1 0 0 0 112 23 NA NA NA NA NA NA 10248 XM_029337210.2 1309 1199 724 1301 1460 A1L2H9 2.03e-65 Replication protein A 32 kDa subunit-B (RP-A p32) (Replication factor A protein 2) (RF-A protein 2) (Replication protein A 34 kDa subunit) (RP-A p34) Xenopus laevis (African clawed frog) base-excision repair [GO:0006284]; DNA replication [GO:0006260]; DNA replication checkpoint signaling [GO:0000076]; double-strand break repair via homologous recombination [GO:0000724]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; protein localization to chromosome [GO:0034502]; regulation of DNA damage checkpoint [GO:2000001]; telomere maintenance [GO:0000723] GO:0000076; GO:0000723; GO:0000724; GO:0000785; GO:0003684; GO:0003697; GO:0005634; GO:0005662; GO:0006260; GO:0006284; GO:0006289; GO:0006298; GO:0016605; GO:0034502; GO:2000001 10249 XM_029335464.2 65 35 55 53 141 NA NA NA NA NA NA 10250 XR_006394578.1 21 24 14 13 26 Q9NBX4 3.02e-28 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 10251 XR_006394578.1 21 24 14 13 26 Q9NBX4 3.02e-28 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 10252 XM_029336062.2 11 29 3 7 49 Q708S7 3.74e-49 Acid-sensing ion channel 1A (ASIC1-A) (Acid-sensing ion channel 1.2-A) (Amiloride-sensitive cation channel 2-B, neuronal-A) (ZASIC1.2) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to pH [GO:0071467]; protein homotrimerization [GO:0070207]; sodium ion transmembrane transport [GO:0035725] GO:0005261; GO:0005886; GO:0015280; GO:0035725; GO:0044736; GO:0070207; GO:0071467 10253 XR_006393080.1 41 2 25 5 151 NA NA NA NA NA NA 10254 XM_029331043.2 15352 20928 11971 43868 25082 Q6Q2B2 1.47e-33 Muscleblind-like protein 2a (Tmbnl2a) Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0003723; GO:0005634; GO:0005737; GO:0006397; GO:0008380; GO:0046872 10255 XM_044319294.1 38 0 20 81 48 NA NA NA NA NA NA 10256 XR_006395823.1 0 20 11 0 53 NA NA NA NA NA NA 10257 XM_029347567.2 267 281 139 0 58 NA NA NA NA NA NA 10258 XR_006396050.1 706 60 165 213 381 NA NA NA NA NA NA 10259 XM_029345912.2 13 111 9 13 10 NA NA NA NA NA NA 10260 XR_006395238.1 0 43 19 0 69 NA NA NA NA NA NA 10261 XM_044307492.1 5 5 2 0 24 NA NA NA NA NA NA 10262 XM_029338042.2 104 0 408 2 683 Q9FN03 8.61e-44 Ultraviolet-B receptor UVR8 (Protein UV-B RESISTANCE 8) (RCC1 domain-containing protein UVR8) Arabidopsis thaliana (Mouse-ear cress) entrainment of circadian clock [GO:0009649]; response to UV [GO:0009411]; response to UV-B [GO:0010224] GO:0000785; GO:0003682; GO:0005085; GO:0005634; GO:0005829; GO:0009411; GO:0009536; GO:0009649; GO:0009881; GO:0010224; GO:0042802; GO:0042803 10263 XM_029338042.2 104 0 408 2 683 Q9FN03 8.63e-29 Ultraviolet-B receptor UVR8 (Protein UV-B RESISTANCE 8) (RCC1 domain-containing protein UVR8) Arabidopsis thaliana (Mouse-ear cress) entrainment of circadian clock [GO:0009649]; response to UV [GO:0009411]; response to UV-B [GO:0010224] GO:0000785; GO:0003682; GO:0005085; GO:0005634; GO:0005829; GO:0009411; GO:0009536; GO:0009649; GO:0009881; GO:0010224; GO:0042802; GO:0042803 10264 XM_029338042.2 104 0 408 2 683 Q9FN03 2.35e-22 Ultraviolet-B receptor UVR8 (Protein UV-B RESISTANCE 8) (RCC1 domain-containing protein UVR8) Arabidopsis thaliana (Mouse-ear cress) entrainment of circadian clock [GO:0009649]; response to UV [GO:0009411]; response to UV-B [GO:0010224] GO:0000785; GO:0003682; GO:0005085; GO:0005634; GO:0005829; GO:0009411; GO:0009536; GO:0009649; GO:0009881; GO:0010224; GO:0042802; GO:0042803 10265 XM_029354515.2 5 9 6 3 15 NA NA NA NA NA NA 10266 XM_029340454.2 0 0 72 0 0 Q80XJ3 5.33e-123 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 10267 XM_029340454.2 0 0 72 0 0 Q80XJ3 3.61e-79 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 10268 XM_029340454.2 0 0 72 0 0 Q80XJ3 2.77e-66 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 10269 XM_029353261.2 72 20 41 17 56 NA NA NA NA NA NA 10270 XM_029357864.2 178 61 105 107 131 P51028 9.75e-72 Protein Wnt-8a Danio rerio (Zebrafish) (Brachydanio rerio) anterior/posterior pattern specification [GO:0009952]; brain segmentation [GO:0035284]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation [GO:0060823]; cell fate commitment [GO:0045165]; cell migration involved in gastrulation [GO:0042074]; cell proliferation involved in pronephros development [GO:0039015]; central nervous system development [GO:0007417]; determination of dorsal identity [GO:0048263]; dorsal/ventral pattern formation [GO:0009953]; ectoderm development [GO:0007398]; embryonic axis specification [GO:0000578]; endoderm development [GO:0007492]; eye development [GO:0001654]; hindbrain development [GO:0030902]; mesoderm development [GO:0007498]; mesoderm formation [GO:0001707]; mesodermal cell fate commitment [GO:0001710]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; neural crest cell fate specification [GO:0014036]; neural plate anterior/posterior regionalization [GO:0021999]; neural plate pattern specification [GO:0060896]; neuron differentiation [GO:0030182]; notochord development [GO:0030903]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of fibroblast growth factor receptor signaling pathway [GO:0045743]; positive regulation of gene expression [GO:0010628]; post-anal tail morphogenesis [GO:0036342]; regulation of anterior head development [GO:2000742]; regulation of cell population proliferation [GO:0042127]; somitogenesis [GO:0001756]; Spemann organizer formation [GO:0060061]; spinal cord anterior/posterior patterning [GO:0021512]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in dorsal/ventral axis specification [GO:0044332] GO:0000578; GO:0001654; GO:0001707; GO:0001710; GO:0001756; GO:0005109; GO:0005125; GO:0005615; GO:0007398; GO:0007417; GO:0007492; GO:0007498; GO:0009952; GO:0009953; GO:0009986; GO:0010628; GO:0014036; GO:0016055; GO:0021512; GO:0021999; GO:0030182; GO:0030902; GO:0030903; GO:0035284; GO:0036342; GO:0039015; GO:0042074; GO:0042127; GO:0044332; GO:0045165; GO:0045743; GO:0048263; GO:0060061; GO:0060070; GO:0060823; GO:0060896; GO:0090090; GO:0090263; GO:0097189; GO:2000742 10271 XM_044317905.1 25 44 29 67 49 NA NA NA NA NA NA 10272 XM_044306742.1 0 20 3 7 50 H1AFJ5 1.32e-44 Amiloride-sensitive sodium channel subunit alpha (Alpha-NaCH) (Epithelial Na(+) channel subunit alpha) (Alpha-ENaC) (Nonvoltage-gated sodium channel 1 subunit alpha) (SCNEA) Neoceratodus forsteri (Australian lungfish) (Ceratodus forsteri) sodium ion transmembrane transport [GO:0035725] GO:0001669; GO:0005737; GO:0015280; GO:0016324; GO:0031514; GO:0034706; GO:0035725 10273 XM_029336715.2 942 873 634 1160 979 Q61382 4.52e-60 TNF receptor-associated factor 4 (EC 2.3.2.27) (Cysteine-rich motif associated to RING and Traf domains protein 1) Mus musculus (Mouse) activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; innate immune response [GO:0045087]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein kinase activity [GO:0045860]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; respiratory gaseous exchange by respiratory system [GO:0007585]; respiratory tube development [GO:0030323] GO:0001650; GO:0005164; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0005923; GO:0006915; GO:0007250; GO:0007585; GO:0008270; GO:0016740; GO:0019901; GO:0030323; GO:0031625; GO:0031996; GO:0042802; GO:0042981; GO:0043122; GO:0043161; GO:0045087; GO:0045860; GO:0046330; GO:0048471; GO:0050699 10274 XM_044320643.1 71 18 56 28 268 O02751 1.15e-25 Craniofacial development protein 2 (p97 bucentaur protein) Bos taurus (Bovine) chromatin remodeling [GO:0006338] GO:0003824; GO:0005634; GO:0005737; GO:0006338 10275 XM_029328584.2 8 0 0 0 0 P35348 3.71e-36 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) (Alpha-adrenergic receptor 1c) Homo sapiens (Human) activation of phospholipase C activity [GO:0007202]; adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; adult heart development [GO:0007512]; aging [GO:0007568]; apoptotic process [GO:0006915]; calcium ion transport into cytosol [GO:0060402]; cell growth involved in cardiac muscle cell development [GO:0061049]; cell-cell signaling [GO:0007267]; G protein-coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; micturition [GO:0060073]; multicellular organism aging [GO:0010259]; negative regulation of autophagy [GO:0010507]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure [GO:0001985]; negative regulation of Rho protein signal transduction [GO:0035024]; neuron-glial cell signaling [GO:0150099]; norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001994]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; pilomotor reflex [GO:0097195]; positive regulation of action potential [GO:0045760]; positive regulation of cardiac muscle contraction [GO:0060452]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; positive regulation of systemic arterial blood pressure [GO:0003084]; positive regulation of the force of heart contraction by epinephrine-norepinephrine [GO:0001997]; positive regulation of vasoconstriction [GO:0045907]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; response to hormone [GO:0009725]; response to xenobiotic stimulus [GO:0009410]; signal transduction [GO:0007165]; smooth muscle contraction [GO:0006939] GO:0000165; GO:0001985; GO:0001994; GO:0001996; GO:0001997; GO:0003084; GO:0004930; GO:0004937; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0005901; GO:0006915; GO:0006939; GO:0007165; GO:0007186; GO:0007200; GO:0007202; GO:0007204; GO:0007267; GO:0007512; GO:0007568; GO:0008285; GO:0009410; GO:0009725; GO:0010259; GO:0010507; GO:0010613; GO:0030018; GO:0030315; GO:0031965; GO:0032230; GO:0035024; GO:0035556; GO:0042734; GO:0043231; GO:0043410; GO:0045211; GO:0045760; GO:0045907; GO:0045987; GO:0046982; GO:0060073; GO:0060402; GO:0060452; GO:0061049; GO:0070374; GO:0071880; GO:0090037; GO:0097195; GO:0098691; GO:0098978; GO:0098982; GO:0099171; GO:0150099; GO:1903997 10276 XM_044321647.1 658 168 378 129 345 C6FG12 1.21e-30 Protein NLRC5 Ictalurus punctatus (Channel catfish) (Silurus punctatus) innate immune response [GO:0045087] GO:0005524; GO:0005737; GO:0045087 10277 XM_029348679.2 2969 2082 1876 3845 3542 O16118 0 Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Homarus americanus (American lobster) G protein-coupled receptor signaling pathway [GO:0007186] GO:0003924; GO:0005525; GO:0007186; GO:0031683; GO:0046872 10278 XM_044313542.1 7 118 0 15 53 NA NA NA NA NA NA 10279 XM_044309480.1 0 0 0 0 7 NA NA NA NA NA NA 10280 XM_044318796.1 386 283 211 282 520 Q08CX1 1.5e-65 Ras and EF-hand domain-containing protein Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0003924; GO:0005509; GO:0005525; GO:0048471 10281 XM_044318796.1 386 283 211 282 520 Q08CX1 4.63e-28 Ras and EF-hand domain-containing protein Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0003924; GO:0005509; GO:0005525; GO:0048471 10282 XM_029344706.2 9 1 7 0 1 Q6WQJ1 1.36e-147 Diacylglycerol lipase-alpha (DAGL-alpha) (DGL-alpha) (EC 3.1.1.116) (Neural stem cell-derived dendrite regulator) (Sn1-specific diacylglycerol lipase alpha) Mus musculus (Mouse) arachidonic acid metabolic process [GO:0019369]; diacylglycerol catabolic process [GO:0046340]; endocannabinoid signaling pathway [GO:0071926]; G protein-coupled glutamate receptor signaling pathway [GO:0007216]; lipid catabolic process [GO:0016042]; neuroblast proliferation [GO:0007405]; neurogenesis [GO:0022008]; neurotransmitter biosynthetic process [GO:0042136]; regulation of neuroinflammatory response [GO:0150077]; retrograde trans-synaptic signaling by endocannabinoid [GO:0098921] GO:0004465; GO:0004806; GO:0005737; GO:0005886; GO:0007216; GO:0007405; GO:0016042; GO:0016298; GO:0016787; GO:0019369; GO:0022008; GO:0031901; GO:0032590; GO:0032591; GO:0042136; GO:0043196; GO:0045211; GO:0046340; GO:0046872; GO:0071926; GO:0098839; GO:0098921; GO:0150077 10283 XM_044318249.1 106 133 122 189 228 P07314 1.16e-130 Glutathione hydrolase 1 proenzyme (EC 3.4.19.13) (Gamma-glutamyltransferase 1) (Gamma-glutamyltranspeptidase 1) (GGT 1) (EC 2.3.2.2) (Leukotriene-C4 hydrolase) (EC 3.4.19.14) (CD antigen CD224) [Cleaved into: Glutathione hydrolase 1 heavy chain; Glutathione hydrolase 1 light chain] Rattus norvegicus (Rat) aging [GO:0007568]; amino acid metabolic process [GO:0006520]; cellular response to oxidative stress [GO:0034599]; cysteine biosynthetic process [GO:0019344]; fatty acid metabolic process [GO:0006631]; glutamate metabolic process [GO:0006536]; glutathione biosynthetic process [GO:0006750]; glutathione catabolic process [GO:0006751]; hepatoblast differentiation [GO:0061017]; hepatocyte differentiation [GO:0070365]; leukotriene D4 biosynthetic process [GO:1901750]; leukotriene metabolic process [GO:0006691]; liver regeneration [GO:0097421]; peptide modification [GO:0031179]; proteolysis [GO:0006508]; regulation of immune system process [GO:0002682]; regulation of inflammatory response [GO:0050727]; response to alcohol [GO:0097305]; response to estradiol [GO:0032355]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]; spermatogenesis [GO:0007283]; zymogen activation [GO:0031638] GO:0000048; GO:0002682; GO:0002951; GO:0005615; GO:0005886; GO:0006508; GO:0006520; GO:0006536; GO:0006631; GO:0006691; GO:0006750; GO:0006751; GO:0007283; GO:0007568; GO:0016755; GO:0019344; GO:0031179; GO:0031638; GO:0031982; GO:0032355; GO:0032496; GO:0034599; GO:0034612; GO:0036374; GO:0050727; GO:0061017; GO:0070365; GO:0097305; GO:0097421; GO:0102953; GO:0103068; GO:1901750 10284 XM_029342746.2 163 206 29 165 268 NA NA NA NA NA NA 10285 XR_006396538.1 20 22 15 14 39 NA NA NA NA NA NA 10286 XM_044314211.1 275 524 430 909 1311 Q80XJ3 1.06e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 10287 XM_029357326.2 2280 1296 925 2703 2344 Q6VAB6 2.01e-85 Kinase suppressor of Ras 2 (hKSR2) (EC 2.7.11.1) Homo sapiens (Human) calcium-mediated signaling [GO:0019722]; positive regulation of cold-induced thermogenesis [GO:0120162]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; signal transduction [GO:0007165] GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006468; GO:0007165; GO:0007265; GO:0019722; GO:0046872; GO:0106310; GO:0120162 10288 XM_029357326.2 2280 1296 925 2703 2344 Q6VAB6 3.06e-22 Kinase suppressor of Ras 2 (hKSR2) (EC 2.7.11.1) Homo sapiens (Human) calcium-mediated signaling [GO:0019722]; positive regulation of cold-induced thermogenesis [GO:0120162]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; signal transduction [GO:0007165] GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006468; GO:0007165; GO:0007265; GO:0019722; GO:0046872; GO:0106310; GO:0120162 10289 XM_044329074.1 14 17 20 21 24 NA NA NA NA NA NA 10290 XR_003825122.2 13 32 0 17 9 NA NA NA NA NA NA 10291 XM_029356794.2 1117 1150 762 1251 1090 P28568 8.7e-120 Solute carrier family 2, facilitated glucose transporter member 3 (CEF-GT3) (Glucose transporter type 3) (GLUT-3) Gallus gallus (Chicken) dehydroascorbic acid transport [GO:0070837]; galactose transmembrane transport [GO:0015757]; glucose import [GO:0046323]; glucose transmembrane transport [GO:1904659]; monosaccharide transmembrane transport [GO:0015749] GO:0005354; GO:0005355; GO:0005536; GO:0005615; GO:0005886; GO:0015149; GO:0015749; GO:0015757; GO:0016020; GO:0042995; GO:0043204; GO:0046323; GO:0055056; GO:0070837; GO:1904659 10292 XM_029340565.2 186 142 159 208 223 Q9VH19 2.22e-160 Leishmanolysin-like peptidase (EC 3.4.24.-) (Invadolysin) Drosophila melanogaster (Fruit fly) brain development [GO:0007420]; cell adhesion [GO:0007155]; cell division [GO:0051301]; centrosome duplication [GO:0051298]; chromatin remodeling [GO:0006338]; electron transport chain [GO:0022900]; germ cell migration [GO:0008354]; gonad development [GO:0008406]; imaginal disc development [GO:0007444]; lipid storage [GO:0019915]; mitotic centrosome separation [GO:0007100]; mitotic chromosome condensation [GO:0007076]; mitotic spindle organization [GO:0007052]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; proteolysis [GO:0006508]; regulation of choline O-acetyltransferase activity [GO:1902769] GO:0004222; GO:0005737; GO:0006338; GO:0006508; GO:0007052; GO:0007076; GO:0007100; GO:0007155; GO:0007420; GO:0007444; GO:0008233; GO:0008354; GO:0008406; GO:0016020; GO:0019915; GO:0022900; GO:0045842; GO:0046872; GO:0051298; GO:0051301; GO:1902769 10293 XM_029350889.2 369 69 74 164 178 A6H603 1.6e-105 NACHT domain- and WD repeat-containing protein 1 Mus musculus (Mouse) negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of gene expression [GO:0010628] GO:0005524; GO:0005730; GO:0005829; GO:0010628; GO:0032088 10294 XM_044328462.1 212 66 231 77 213 Q3KP44 1e-40 Ankyrin repeat domain-containing protein 55 Homo sapiens (Human) NA NA 10295 XM_044328462.1 212 66 231 77 213 Q3KP44 1e-40 Ankyrin repeat domain-containing protein 55 Homo sapiens (Human) NA NA 10296 XR_003826736.2 61 109 43 101 57 NA NA NA NA NA NA 10297 XM_044320812.1 14 65 13 38 24 NA NA NA NA NA NA 10298 XM_044323841.1 110 44 60 292 119 B8V7S0 1.43e-58 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 10299 XR_003825204.2 578 764 440 580 680 NA NA NA NA NA NA 10300 XM_044316977.1 0 0 0 0 23 NA NA NA NA NA NA 10301 XM_044320378.1 63 80 14 148 907 Q14517 0 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 10302 XM_044320378.1 63 80 14 148 907 Q14517 6.55e-55 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 10303 XM_044320378.1 63 80 14 148 907 Q14517 1.08e-34 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 10304 XM_044318053.1 5 11 12 89 16 Q92752 8.8e-70 Tenascin-R (TN-R) (Janusin) (Restrictin) Homo sapiens (Human) associative learning [GO:0008306]; axon extension involved in regeneration [GO:0048677]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198]; locomotory exploration behavior [GO:0035641]; long-term synaptic potentiation [GO:0060291]; negative regulation of axon extension involved in regeneration [GO:0048692]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of neuron projection development [GO:0010977]; negative regulation of synaptic transmission [GO:0050805]; neuroblast migration [GO:0097402]; neuromuscular process controlling balance [GO:0050885]; neuron cell-cell adhesion [GO:0007158]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transmission of nerve impulse [GO:0051971]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of cell migration [GO:0030334]; synapse organization [GO:0050808]; synaptic transmission, glutamatergic [GO:0035249]; telencephalon cell migration [GO:0022029] GO:0005102; GO:0005576; GO:0005615; GO:0007155; GO:0007158; GO:0007411; GO:0008306; GO:0009986; GO:0010977; GO:0022029; GO:0022408; GO:0030155; GO:0030198; GO:0030334; GO:0035249; GO:0035641; GO:0045121; GO:0045595; GO:0048677; GO:0048692; GO:0050805; GO:0050808; GO:0050885; GO:0051968; GO:0051971; GO:0060291; GO:0062023; GO:0072534; GO:0090733; GO:0097402; GO:0098685; GO:0098978 10305 XR_003825435.2 21 45 10 7 32 NA NA NA NA NA NA 10306 XM_044328399.1 2 6 0 1 19 NA NA NA NA NA NA 10307 XM_044307174.1 18 47 30 72 46 NA NA NA NA NA NA 10308 XM_044316911.1 0 7 0 0 5 NA NA NA NA NA NA 10309 XR_006394993.1 214 158 79 111 113 NA NA NA NA NA NA 10310 XM_044314543.1 1065 812 459 2388 760 NA NA NA NA NA NA 10311 XR_006393596.1 442 388 100 204 204 NA NA NA NA NA NA 10312 XM_044309159.1 163 16 58 167 15 NA NA NA NA NA NA 10313 XM_029343902.2 0 0 0 0 7 Q96RW7 2.53e-70 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 10314 XM_029343902.2 0 0 0 0 7 Q96RW7 5.75e-66 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 10315 XM_029343902.2 0 0 0 0 7 Q96RW7 8.1e-65 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 10316 XM_029343902.2 0 0 0 0 7 Q96RW7 1.14e-63 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 10317 XM_029343902.2 0 0 0 0 7 Q96RW7 1.11e-62 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 10318 XM_029343902.2 0 0 0 0 7 Q96RW7 9.14e-52 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 10319 XM_029343902.2 0 0 0 0 7 Q96RW7 7.44e-49 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 10320 XM_029343902.2 0 0 0 0 7 Q96RW7 1.67e-48 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 10321 XM_044318428.1 1189 993 865 1575 1208 NA NA NA NA NA NA 10322 XM_044325321.1 85 44 44 45 197 NA NA NA NA NA NA 10323 XM_044317396.1 188 168 0 18 93 P83858 3.65e-28 Pyroglutamylated RF-amide peptide receptor (AQ27) (G-protein coupled receptor 103) (Orexigenic neuropeptide QRFP receptor) (SP9155) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:0097730 10324 XM_044315949.1 105 0 17 24 19 B8VIU6 8.86e-55 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 10325 XM_029336781.2 828 585 416 656 1058 Q5ZLM0 0 Parafibromin (Cell division cycle protein 73 homolog) Gallus gallus (Chicken) cell cycle [GO:0007049]; endodermal cell fate commitment [GO:0001711]; histone modification [GO:0016570]; mRNA polyadenylation [GO:0006378]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cell cycle G1/S phase transition [GO:1902808]; positive regulation of mRNA 3'-end processing [GO:0031442]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; positive regulation of Wnt signaling pathway [GO:0030177]; recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex [GO:0034402]; stem cell population maintenance [GO:0019827]; transcription elongation by RNA polymerase II promoter [GO:0006368] GO:0000122; GO:0000993; GO:0001711; GO:0005634; GO:0006368; GO:0006378; GO:0007049; GO:0008285; GO:0016570; GO:0016593; GO:0019827; GO:0030177; GO:0031442; GO:0032968; GO:0034402; GO:0045638; GO:1902808; GO:2000134 10326 XM_029333372.2 800 763 280 581 334 NA NA NA NA NA NA 10327 XR_003827674.2 35 30 72 36 317 NA NA NA NA NA NA 10328 XM_029341738.2 66 66 7 51 49 A0A0C2SRU0 2.72e-72 Decarboxylase iboD (EC 4.1.1.-) (Ibotenic acid biosynthesis cluster protein D) Amanita muscaria (strain Koide BX008) phospholipid biosynthetic process [GO:0008654] GO:0004609; GO:0008654 10329 XM_044318285.1 0 0 3 3 28 NA NA NA NA NA NA 10330 XM_029343280.2 74 76 39 39 97 Q5RCP7 0 Centrosomal protein of 76 kDa (Cep76) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) regulation of centriole replication [GO:0046599] GO:0005737; GO:0005814; GO:0046599 10331 XM_044310925.1 46 148 38 113 24 NA NA NA NA NA NA 10332 XM_044311880.1 28 20 23 18 55 NA NA NA NA NA NA 10333 XM_029324565.2 30 3 21 22 40 P04323 3.22e-86 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 10334 XR_006396043.1 180 215 197 281 215 NA NA NA NA NA NA 10335 XM_029352579.2 1327 1048 606 1471 2120 Q9LMI7 3.75e-102 Putative acyl-coenzyme A oxidase 3.2, peroxisomal (EC 1.3.3.6) Arabidopsis thaliana (Mouse-ear cress) fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; lipid homeostasis [GO:0055088] GO:0003997; GO:0005504; GO:0005777; GO:0033540; GO:0050660; GO:0055088; GO:0071949 10336 XM_029347228.2 48 8 28 5 101 NA NA NA NA NA NA 10337 XM_029340162.2 43 51 36 24 18 NA NA NA NA NA NA 10338 XM_029350153.2 2342 1958 1052 1586 1216 Q9WU20 0 Methylenetetrahydrofolate reductase (NADPH) (EC 1.5.1.53) Mus musculus (Mouse) heterochromatin organization [GO:0070828]; homocysteine metabolic process [GO:0050667]; methionine biosynthetic process [GO:0009086]; methionine metabolic process [GO:0006555]; neural tube closure [GO:0001843]; regulation of histone methylation [GO:0031060]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653] GO:0001843; GO:0004489; GO:0005829; GO:0006555; GO:0009086; GO:0031060; GO:0035999; GO:0044877; GO:0045202; GO:0046653; GO:0050660; GO:0050661; GO:0050667; GO:0070828; GO:0071949; GO:0072341; GO:0106313 10339 XM_044328743.1 70 146 36 50 100 NA NA NA NA NA NA 10340 XM_044307343.1 28 20 44 33 99 P70490 1.36e-21 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 10341 XM_029358226.2 339 376 178 364 60 NA NA NA NA NA NA 10342 XM_029350967.2 148 85 61 53 111 Q08CH3 6.41e-70 MPN domain-containing protein (EC 3.4.-.-) Danio rerio (Zebrafish) (Brachydanio rerio) chromatin remodeling [GO:0006338]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteolysis [GO:0006508] GO:0003713; GO:0006338; GO:0006508; GO:0008237; GO:0042393; GO:0045944; GO:0046872 10343 XM_029350967.2 148 85 61 53 111 Q08CH3 3.29e-38 MPN domain-containing protein (EC 3.4.-.-) Danio rerio (Zebrafish) (Brachydanio rerio) chromatin remodeling [GO:0006338]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteolysis [GO:0006508] GO:0003713; GO:0006338; GO:0006508; GO:0008237; GO:0042393; GO:0045944; GO:0046872 10344 XM_029348067.2 0 0 0 10 0 NA NA NA NA NA NA 10345 XR_006391512.1 1049 718 417 640 824 NA NA NA NA NA NA 10346 XM_029330227.2 2543 3702 1717 3393 2035 NA NA NA NA NA NA 10347 XM_044308153.1 460 621 200 390 387 P11182 3.54e-175 Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial (EC 2.3.1.168) (52 kDa mitochondrial autoantigen of primary biliary cirrhosis) (Branched chain 2-oxo-acid dehydrogenase complex component E2) (BCOADC-E2) (Branched-chain alpha-keto acid dehydrogenase complex component E2) (BCKAD-E2) (BCKADE2) (Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex) (Dihydrolipoamide branched chain transacylase) (Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase) Homo sapiens (Human) branched-chain amino acid catabolic process [GO:0009083] GO:0005737; GO:0005739; GO:0005759; GO:0005829; GO:0005947; GO:0009083; GO:0015630; GO:0016407; GO:0031405; GO:0031625; GO:0042645; GO:0043754 10348 XM_044314028.1 32 221 96 19 67 Q9BWT3 0 Poly(A) polymerase gamma (PAP-gamma) (EC 2.7.7.19) (Neo-poly(A) polymerase) (Neo-PAP) (Polynucleotide adenylyltransferase gamma) (SRP RNA 3'-adenylating enzyme) (Signal recognition particle RNA-adenylating enzyme) (SRP RNA-adenylating enzyme) Homo sapiens (Human) mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631] GO:0003723; GO:0004652; GO:0005524; GO:0005634; GO:0005654; GO:0005829; GO:0006378; GO:0016020; GO:0016604; GO:0043631; GO:0046872 10349 XM_044314925.1 127 0 0 0 0 Q2TBP0 9.57e-41 Proteasome subunit beta type-7 (EC 3.4.25.1) Bos taurus (Bovine) proteolysis involved in protein catabolic process [GO:0051603] GO:0004298; GO:0005634; GO:0005737; GO:0005839; GO:0019774; GO:0051603 10350 XM_044314925.1 127 0 0 0 0 Q2TBP0 9.57e-41 Proteasome subunit beta type-7 (EC 3.4.25.1) Bos taurus (Bovine) proteolysis involved in protein catabolic process [GO:0051603] GO:0004298; GO:0005634; GO:0005737; GO:0005839; GO:0019774; GO:0051603 10351 XM_029358583.2 1569 1362 821 1366 1835 C9J069 1.16e-29 Apical junction component 1 homolog Homo sapiens (Human) cell-cell junction organization [GO:0045216] GO:0005886; GO:0005912; GO:0005929; GO:0016324; GO:0043296; GO:0045216 10352 XM_044329081.1 62 31 134 118 110 NA NA NA NA NA NA 10353 XM_029327460.2 8075 9943 4552 7349 4669 O61231 4e-129 60S ribosomal protein L10 (QM protein homolog) (dQM) Drosophila melanogaster (Fruit fly) cytoplasmic translation [GO:0002181]; ribosomal large subunit assembly [GO:0000027] GO:0000027; GO:0002181; GO:0003735; GO:0005737; GO:0022625; GO:0022626; GO:0043025 10354 XM_029331580.2 36 0 0 28 49 Q5RAM2 7.94e-58 Estrogen-related receptor gamma (Estrogen receptor-related protein 3) (Nuclear receptor subfamily 3 group B member 3) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) regulation of DNA-templated transcription [GO:0006355]; retinoic acid receptor signaling pathway [GO:0048384] GO:0003707; GO:0004879; GO:0005496; GO:0005654; GO:0006355; GO:0008270; GO:0043565; GO:0048384 10355 XM_044308454.1 176 63 203 330 1167 NA NA NA NA NA NA 10356 XM_029341208.2 0 163 0 35 0 Q91175 8.24e-43 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (MAR1) Oryzias latipes (Japanese rice fish) (Japanese killifish) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of vasoconstriction [GO:0045907] GO:0001996; GO:0004930; GO:0004937; GO:0005886; GO:0007200; GO:0007204; GO:0007267; GO:0043410; GO:0045907; GO:0071880 10357 XM_029334214.2 366 281 269 255 166 B1H3D5 4.7e-25 Poly(U)-specific endoribonuclease (EC 4.6.1.-) (Protein endoU) (Uridylate-specific endoribonuclease) (XendoU) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0003723; GO:0004521; GO:0005634; GO:0016829; GO:0046872 10358 XM_029337317.2 372 307 296 239 419 Q0V9C9 1.63e-55 Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) innate immune response [GO:0045087]; regulation of oxidoreductase activity [GO:0051341]; regulation of protein complex stability [GO:0061635] GO:0005634; GO:0005737; GO:0005739; GO:0045087; GO:0051341; GO:0061635 10359 XM_029340415.2 6255 3978 3107 8350 4079 Q9NYT6 2.01e-40 Zinc finger protein 226 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 10360 XM_029340415.2 6255 3978 3107 8350 4079 Q9NYT6 4.51e-24 Zinc finger protein 226 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 10361 XM_029333531.2 1777 522 612 1742 767 E1C760 9.94e-118 UV-stimulated scaffold protein A Gallus gallus (Chicken) protein ubiquitination [GO:0016567]; response to UV [GO:0009411]; transcription-coupled nucleotide-excision repair [GO:0006283] GO:0000993; GO:0005694; GO:0006283; GO:0009411; GO:0016567 10362 XM_044320870.1 128 189 118 2686 432 Q96PM5 2.56e-28 RING finger and CHY zinc finger domain-containing protein 1 (EC 2.3.2.27) (Androgen receptor N-terminal-interacting protein) (CH-rich-interacting match with PLAG1) (E3 ubiquitin-protein ligase Pirh2) (RING finger protein 199) (RING-type E3 ubiquitin transferase RCHY1) (Zinc finger protein 363) (p53-induced RING-H2 protein) (hPirh2) Homo sapiens (Human) error-free translesion synthesis [GO:0070987]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; protein autoubiquitination [GO:0051865]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000151; GO:0002039; GO:0004842; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006511; GO:0008270; GO:0016567; GO:0016607; GO:0031398; GO:0032436; GO:0042803; GO:0043231; GO:0051865; GO:0061630; GO:0070987 10363 XM_029356828.2 50 4 6 140 25 NA NA NA NA NA NA 10364 XR_006392509.1 68 38 0 26 25 NA NA NA NA NA NA 10365 XM_044322984.1 3902 3620 1616 3045 2142 P0CZ23 1.12e-90 Acyl-coenzyme A oxidase 3, peroxisomal (AOX 3) (Acyl-CoA oxidase 3) (EC 1.3.3.6) (Medium-chain acyl-CoA oxidase) (AtCX3) Arabidopsis thaliana (Mouse-ear cress) fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; lipid homeostasis [GO:0055088]; medium-chain fatty acid metabolic process [GO:0051791] GO:0003997; GO:0005504; GO:0005576; GO:0005777; GO:0006635; GO:0033540; GO:0050660; GO:0051791; GO:0055088; GO:0071949 10366 XM_044312046.1 6 0 3 2 3 NA NA NA NA NA NA 10367 XM_044321758.1 9 0 0 0 0 NA NA NA NA NA NA 10368 XM_044328762.1 1090 1143 281 1855 1038 P12716 0 Actin, cytoplasmic (EC 3.6.4.-) [Cleaved into: Actin, cytoplasmic, intermediate form] Pisaster ochraceus (Ochre sea star) (Asterias ochracea) NA GO:0005524; GO:0005737; GO:0005856; GO:0016787 10369 XM_044318100.1 10 12 23 18 108 NA NA NA NA NA NA 10370 XM_044327583.1 28 108 20 34 19 A7YSY2 0 Ribosome biogenesis protein SPATA5L1 (EC 3.6.4.10) (Spermatogenesis-associated protein 5-like protein 1) Bos taurus (Bovine) ribosomal large subunit biogenesis [GO:0042273] GO:0005524; GO:0005634; GO:0005737; GO:0005819; GO:0016887; GO:0042273; GO:1990275 10371 XM_044310305.1 31 1 5 28 7 Q80XJ3 2.24e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 10372 XM_029324877.2 5067 2452 657 3758 2740 NA NA NA NA NA NA 10373 XM_029342460.2 15 0 0 0 19 NA NA NA NA NA NA 10374 XM_044325615.1 712 1070 1031 698 617 O43399 2.69e-21 Tumor protein D54 (hD54) (Tumor protein D52-like 2) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; regulation of cell population proliferation [GO:0042127] GO:0003723; GO:0005737; GO:0005975; GO:0042127; GO:0042803; GO:0048471 10375 XM_044315741.1 0 7 15 0 58 P49013 1.38e-68 Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374 10376 XM_044315741.1 0 7 15 0 58 P49013 1.23e-66 Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374 10377 XM_044315741.1 0 7 15 0 58 P49013 1.41e-55 Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374 10378 XM_044315741.1 0 7 15 0 58 P49013 2.23e-54 Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374 10379 XM_029330977.2 2370 1777 1883 2166 1941 Q9Y2L9 1.08e-55 Leucine-rich repeat and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1) (Neuronal protein 81) (NP81) Homo sapiens (Human) cellular response to chemokine [GO:1990869]; negative regulation of GTPase activity [GO:0034260]; negative regulation of T cell migration [GO:2000405] GO:0005737; GO:0034260; GO:1990869; GO:2000405 10380 XM_029330977.2 2370 1777 1883 2166 1941 Q9Y2L9 4.1e-32 Leucine-rich repeat and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1) (Neuronal protein 81) (NP81) Homo sapiens (Human) cellular response to chemokine [GO:1990869]; negative regulation of GTPase activity [GO:0034260]; negative regulation of T cell migration [GO:2000405] GO:0005737; GO:0034260; GO:1990869; GO:2000405 10381 XM_044312122.1 198 9 60 20 504 NA NA NA NA NA NA 10382 XM_044323192.1 53 17 57 100 159 P70490 8.31e-21 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 10383 XM_044326423.1 2 1 1 4 8 NA NA NA NA NA NA 10384 XM_044309999.1 7 0 0 15 34 NA NA NA NA NA NA 10385 XM_029351704.2 0 0 0 0 351 Q9H089 2.31e-171 Large subunit GTPase 1 homolog (hLsg1) (EC 3.6.1.-) Homo sapiens (Human) nuclear export [GO:0051168]; protein transport [GO:0015031]; ribosomal subunit export from nucleus [GO:0000054] GO:0000054; GO:0003924; GO:0005525; GO:0005654; GO:0005783; GO:0005829; GO:0015030; GO:0015031; GO:0016020; GO:0016604; GO:0051168 10386 XR_006393662.1 29 2 29 97 132 Q9NZJ4 2.59e-97 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 10387 XR_006393662.1 29 2 29 97 132 Q9NZJ4 3.32e-79 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 10388 XR_006393662.1 29 2 29 97 132 Q9NZJ4 3.32e-79 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 10389 XR_006393662.1 29 2 29 97 132 Q9NZJ4 3.32e-79 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 10390 XR_006393662.1 29 2 29 97 132 Q9NZJ4 1.7e-74 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 10391 XR_006393662.1 29 2 29 97 132 Q9NZJ4 1.7e-74 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 10392 XR_006393662.1 29 2 29 97 132 Q9NZJ4 5.63e-55 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 10393 XR_006393662.1 29 2 29 97 132 Q9NZJ4 3.69e-40 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 10394 XR_006393662.1 29 2 29 97 132 Q9NZJ4 5.36e-32 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 10395 XR_006393662.1 29 2 29 97 132 Q9NZJ4 5.36e-32 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 10396 XR_006393662.1 29 2 29 97 132 Q9NZJ4 1.14e-31 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 10397 XR_006393662.1 29 2 29 97 132 Q9NZJ4 1.14e-31 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 10398 XR_006393662.1 29 2 29 97 132 Q9NZJ4 2.56e-30 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 10399 XR_006393662.1 29 2 29 97 132 Q9NZJ4 2.07e-26 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 10400 XR_006393662.1 29 2 29 97 132 Q9NZJ4 2.07e-26 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 10401 XR_006393662.1 29 2 29 97 132 Q9NZJ4 1.21e-22 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 10402 XR_006393662.1 29 2 29 97 132 Q9NZJ4 1.99e-21 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 10403 XM_029349760.2 53 183 196 200 274 NA NA NA NA NA NA 10404 XM_044310743.1 73 30 17 82 4 NA NA NA NA NA NA 10405 XM_029327299.2 0 0 0 0 14 Q09575 2.29e-26 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 10406 XM_029352915.2 328 190 194 247 166 Q03393 6.82e-55 6-pyruvoyl tetrahydrobiopterin synthase (PTP synthase) (PTPS) (EC 4.2.3.12) Homo sapiens (Human) amino acid metabolic process [GO:0006520]; central nervous system development [GO:0007417]; tetrahydrobiopterin biosynthetic process [GO:0006729] GO:0003874; GO:0005737; GO:0005739; GO:0005829; GO:0006520; GO:0006729; GO:0007417; GO:0042802; GO:0046872 10407 XM_029344423.2 124 109 449 70 121 Q8VCH8 2.14e-75 UBX domain-containing protein 4 (Erasin) (UBX domain-containing protein 2) Mus musculus (Mouse) response to unfolded protein [GO:0006986]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0005635; GO:0005783; GO:0005789; GO:0005829; GO:0006986; GO:0030433 10408 XM_029342218.2 416 211 224 347 406 Q6NRG6 7.06e-149 Spindle assembly abnormal protein 6 homolog Xenopus laevis (African clawed frog) centriole replication [GO:0007099] GO:0005737; GO:0005814; GO:0007099; GO:0098536 10409 XM_044323207.1 0 0 7 25 2 NA NA NA NA NA NA 10410 XM_044320497.1 510 215 154 565 647 Q7RTR2 5.02e-68 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 10411 XM_044320497.1 510 215 154 565 647 Q7RTR2 1.36e-65 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 10412 XM_044320497.1 510 215 154 565 647 Q7RTR2 1.92e-57 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 10413 XM_044320497.1 510 215 154 565 647 Q7RTR2 1.29e-40 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 10414 XM_044320497.1 510 215 154 565 647 Q7RTR2 1.64e-28 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 10415 XR_006392734.1 95 25 14 14 2 NA NA NA NA NA NA 10416 XR_006395249.1 77 13 16 51 39 NA NA NA NA NA NA 10417 XR_006396448.1 192 58 159 223 209 NA NA NA NA NA NA 10418 XR_006392217.1 119 70 75 54 193 NA NA NA NA NA NA 10419 XR_006397203.1 0 0 6 0 4 NA NA NA NA NA NA 10420 XM_044309878.1 12 0 0 0 0 NA NA NA NA NA NA 10421 XM_044328488.1 694 483 442 174 1436 NA NA NA NA NA NA 10422 XM_029335595.2 927 407 365 2168 2804 NA NA NA NA NA NA 10423 XR_006392144.1 87 111 50 147 170 NA NA NA NA NA NA 10424 XM_029334391.2 339 398 192 333 228 NA NA NA NA NA NA 10425 XM_044318290.1 478 1219 663 1025 744 Q9Y5Z4 3.08e-25 Heme-binding protein 2 (Placental protein 23) (PP23) (Protein SOUL) Homo sapiens (Human) negative regulation of mitochondrial membrane potential [GO:0010917]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of necrotic cell death [GO:0010940] GO:0005576; GO:0005737; GO:0005739; GO:0010917; GO:0010940; GO:0020037; GO:0035578; GO:0035794; GO:0070062 10426 XM_044318290.1 478 1219 663 1025 744 Q9Y5Z4 5.22e-25 Heme-binding protein 2 (Placental protein 23) (PP23) (Protein SOUL) Homo sapiens (Human) negative regulation of mitochondrial membrane potential [GO:0010917]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of necrotic cell death [GO:0010940] GO:0005576; GO:0005737; GO:0005739; GO:0010917; GO:0010940; GO:0020037; GO:0035578; GO:0035794; GO:0070062 10427 XM_029356388.2 166 89 68 89 43 NA NA NA NA NA NA 10428 XM_044310703.1 67 43 32 85 132 NA NA NA NA NA NA 10429 XM_044311314.1 9 8 7 70 0 NA NA NA NA NA NA 10430 XM_044321584.1 22 5 29 8 109 NA NA NA NA NA NA 10431 XM_044327105.1 668 611 742 768 1325 B8RJM0 0 Uncharacterized skeletal organic matrix protein 3 (Uncharacterized SOMP-3) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 10432 XM_044317597.1 0 0 0 0 28 NA NA NA NA NA NA 10433 XR_006392503.1 19 0 24 4 0 NA NA NA NA NA NA 10434 XM_044319970.1 100 20 35 225 341 D3YXG0 0 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 10435 XM_044319970.1 100 20 35 225 341 D3YXG0 1.29e-151 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 10436 XM_044319970.1 100 20 35 225 341 D3YXG0 2.91e-141 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 10437 XM_044319970.1 100 20 35 225 341 D3YXG0 1.61e-126 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 10438 XM_044319970.1 100 20 35 225 341 D3YXG0 8.22e-97 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 10439 XM_044319970.1 100 20 35 225 341 D3YXG0 8.75e-92 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 10440 XM_044319970.1 100 20 35 225 341 D3YXG0 2.93e-89 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 10441 XM_044319970.1 100 20 35 225 341 D3YXG0 1.92e-88 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 10442 XM_044319970.1 100 20 35 225 341 D3YXG0 7.26e-84 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 10443 XM_044319970.1 100 20 35 225 341 D3YXG0 1.43e-81 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 10444 XM_044319970.1 100 20 35 225 341 D3YXG0 2.58e-81 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 10445 XM_044319970.1 100 20 35 225 341 D3YXG0 9.96e-30 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 10446 XM_044319970.1 100 20 35 225 341 D3YXG0 3.79e-26 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 10447 XM_029342509.2 97 24 41 49 101 NA NA NA NA NA NA 10448 XM_044323418.1 63 4 58 37 118 P35953 7.06e-34 Very low-density lipoprotein receptor (VLDL receptor) (VLDL-R) Oryctolagus cuniculus (Rabbit) cholesterol metabolic process [GO:0008203]; dendrite morphogenesis [GO:0048813]; glycoprotein transport [GO:0034436]; lipid transport [GO:0006869]; positive regulation of dendrite development [GO:1900006]; positive regulation of protein kinase activity [GO:0045860]; receptor-mediated endocytosis [GO:0006898]; ventral spinal cord development [GO:0021517]; very-low-density lipoprotein particle clearance [GO:0034447] GO:0005509; GO:0005905; GO:0006869; GO:0006898; GO:0008203; GO:0021517; GO:0030229; GO:0034185; GO:0034189; GO:0034361; GO:0034436; GO:0034447; GO:0038025; GO:0043235; GO:0045860; GO:0048306; GO:0048813; GO:1900006 10449 XM_044323418.1 63 4 58 37 118 P35953 2.24e-25 Very low-density lipoprotein receptor (VLDL receptor) (VLDL-R) Oryctolagus cuniculus (Rabbit) cholesterol metabolic process [GO:0008203]; dendrite morphogenesis [GO:0048813]; glycoprotein transport [GO:0034436]; lipid transport [GO:0006869]; positive regulation of dendrite development [GO:1900006]; positive regulation of protein kinase activity [GO:0045860]; receptor-mediated endocytosis [GO:0006898]; ventral spinal cord development [GO:0021517]; very-low-density lipoprotein particle clearance [GO:0034447] GO:0005509; GO:0005905; GO:0006869; GO:0006898; GO:0008203; GO:0021517; GO:0030229; GO:0034185; GO:0034189; GO:0034361; GO:0034436; GO:0034447; GO:0038025; GO:0043235; GO:0045860; GO:0048306; GO:0048813; GO:1900006 10450 XM_044323418.1 63 4 58 37 118 P35953 6.78e-25 Very low-density lipoprotein receptor (VLDL receptor) (VLDL-R) Oryctolagus cuniculus (Rabbit) cholesterol metabolic process [GO:0008203]; dendrite morphogenesis [GO:0048813]; glycoprotein transport [GO:0034436]; lipid transport [GO:0006869]; positive regulation of dendrite development [GO:1900006]; positive regulation of protein kinase activity [GO:0045860]; receptor-mediated endocytosis [GO:0006898]; ventral spinal cord development [GO:0021517]; very-low-density lipoprotein particle clearance [GO:0034447] GO:0005509; GO:0005905; GO:0006869; GO:0006898; GO:0008203; GO:0021517; GO:0030229; GO:0034185; GO:0034189; GO:0034361; GO:0034436; GO:0034447; GO:0038025; GO:0043235; GO:0045860; GO:0048306; GO:0048813; GO:1900006 10451 XM_029344296.2 722 767 553 643 751 Q15717 7.22e-60 ELAV-like protein 1 (Hu-antigen R) (HuR) Homo sapiens (Human) 3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA stabilization [GO:0048255]; negative regulation of miRNA-mediated gene silencing [GO:0060965]; positive regulation of translation [GO:0045727]; post-transcriptional gene silencing [GO:0016441]; protein homooligomerization [GO:0051260]; protein import into nucleus [GO:0006606]; regulation of stem cell population maintenance [GO:2000036] GO:0000932; GO:0003723; GO:0003725; GO:0003729; GO:0003730; GO:0005634; GO:0005654; GO:0005737; GO:0005783; GO:0005829; GO:0006606; GO:0010494; GO:0016020; GO:0016441; GO:0016528; GO:0019901; GO:0031410; GO:0035198; GO:0035925; GO:0042803; GO:0045727; GO:0048255; GO:0051260; GO:0060965; GO:0070935; GO:0098794; GO:0098978; GO:0106222; GO:1990904; GO:2000036 10452 XR_006395904.1 0 1 2 0 6 NA NA NA NA NA NA 10453 XR_006393854.1 100 99 64 171 159 NA NA NA NA NA NA 10454 XM_029333126.2 460 417 434 731 580 Q8IWG1 0 Dynein axonemal intermediate chain 3 (Testis development protein NYD-SP29) (WD repeat-containing protein 63) Homo sapiens (Human) cilium movement involved in cell motility [GO:0060294]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; negative regulation of cell migration [GO:0030336]; positive regulation of osteoblast differentiation [GO:0045669] GO:0005737; GO:0005858; GO:0007018; GO:0030336; GO:0034316; GO:0036156; GO:0036159; GO:0045503; GO:0045504; GO:0045669; GO:0060294; GO:0071933 10455 XM_029356223.2 32 29 42 37 86 NA NA NA NA NA NA 10456 XM_029347226.2 58 19 30 58 108 Q2KI24 9.39e-106 Methenyltetrahydrofolate synthase domain-containing protein Bos taurus (Bovine) NA GO:0003723; GO:0005737 10457 XM_044326282.1 120 30 114 71 401 NA NA NA NA NA NA 10458 XM_044322448.1 23 6 5 21 21 Q14833 1.04e-78 Metabotropic glutamate receptor 4 (mGluR4) Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway [GO:0007196]; chemical synaptic transmission [GO:0007268]; G protein-coupled glutamate receptor signaling pathway [GO:0007216]; neurotransmitter secretion [GO:0007269]; positive regulation of MAPK cascade [GO:0043410]; regulation of neuron apoptotic process [GO:0043523]; regulation of synaptic transmission, glutamatergic [GO:0051966] GO:0001640; GO:0004930; GO:0005886; GO:0007196; GO:0007216; GO:0007268; GO:0007269; GO:0008066; GO:0031410; GO:0043410; GO:0043523; GO:0051966; GO:0098793 10459 XR_003823893.2 71 75 66 225 112 NA NA NA NA NA NA 10460 XM_044312206.1 11 0 2 9 19 NA NA NA NA NA NA 10461 XM_029356228.2 5298 5436 4488 4667 2487 O08528 3.91e-111 Hexokinase-2 (EC 2.7.1.1) (Hexokinase type II) (HK II) Mus musculus (Mouse) apoptotic mitochondrial changes [GO:0008637]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; cellular response to leukemia inhibitory factor [GO:1990830]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]; lactation [GO:0007595]; maintenance of protein location in mitochondrion [GO:0072656]; negative regulation of mitochondrial membrane permeability [GO:0035795]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; positive regulation of angiogenesis [GO:0045766]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; regulation of glucose import [GO:0046324]; response to hypoxia [GO:0001666]; response to ischemia [GO:0002931] GO:0001666; GO:0001678; GO:0002931; GO:0004340; GO:0004396; GO:0005524; GO:0005536; GO:0005739; GO:0005741; GO:0005813; GO:0005829; GO:0005886; GO:0006002; GO:0006006; GO:0006096; GO:0007595; GO:0008637; GO:0008865; GO:0016529; GO:0035795; GO:0043231; GO:0045766; GO:0046324; GO:0046835; GO:0051156; GO:0072655; GO:0072656; GO:1904925; GO:1990830; GO:2000378 10462 XM_029356228.2 5298 5436 4488 4667 2487 O08528 1.68e-107 Hexokinase-2 (EC 2.7.1.1) (Hexokinase type II) (HK II) Mus musculus (Mouse) apoptotic mitochondrial changes [GO:0008637]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; cellular response to leukemia inhibitory factor [GO:1990830]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]; lactation [GO:0007595]; maintenance of protein location in mitochondrion [GO:0072656]; negative regulation of mitochondrial membrane permeability [GO:0035795]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; positive regulation of angiogenesis [GO:0045766]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; regulation of glucose import [GO:0046324]; response to hypoxia [GO:0001666]; response to ischemia [GO:0002931] GO:0001666; GO:0001678; GO:0002931; GO:0004340; GO:0004396; GO:0005524; GO:0005536; GO:0005739; GO:0005741; GO:0005813; GO:0005829; GO:0005886; GO:0006002; GO:0006006; GO:0006096; GO:0007595; GO:0008637; GO:0008865; GO:0016529; GO:0035795; GO:0043231; GO:0045766; GO:0046324; GO:0046835; GO:0051156; GO:0072655; GO:0072656; GO:1904925; GO:1990830; GO:2000378 10463 XM_044317333.1 11 22 2 13 6 NA NA NA NA NA NA 10464 XR_006391279.1 6 26 10 13 33 NA NA NA NA NA NA 10465 XR_006393849.1 0 8 5 0 11 NA NA NA NA NA NA 10466 XM_044317823.1 39 5 0 82 3 Q8BZ20 7.03e-61 Protein mono-ADP-ribosyltransferase PARP12 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 12) (ARTD12) (Poly [ADP-ribose] polymerase 12) (PARP-12) (Zinc finger CCCH domain-containing protein 1) Mus musculus (Mouse) protein auto-ADP-ribosylation [GO:0070213] GO:0003950; GO:0005634; GO:0016779; GO:0046872; GO:0070213; GO:0140803; GO:1990404 10467 XM_044326841.1 18 5 59 9 87 Q96RW7 2.87e-46 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 10468 XM_044326841.1 18 5 59 9 87 Q96RW7 6.25e-42 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 10469 XM_044326841.1 18 5 59 9 87 Q96RW7 1.31e-40 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 10470 XM_044326841.1 18 5 59 9 87 Q96RW7 7.92e-40 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 10471 XM_044326841.1 18 5 59 9 87 Q96RW7 2.49e-39 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 10472 XM_044326841.1 18 5 59 9 87 Q96RW7 2.83e-37 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 10473 XM_044326841.1 18 5 59 9 87 Q96RW7 7.79e-37 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 10474 XM_044326841.1 18 5 59 9 87 Q96RW7 5.22e-36 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 10475 XM_044326841.1 18 5 59 9 87 Q96RW7 2.46e-35 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 10476 XM_044326841.1 18 5 59 9 87 Q96RW7 4.49e-35 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 10477 XM_044326841.1 18 5 59 9 87 Q96RW7 5.57e-35 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 10478 XM_044326841.1 18 5 59 9 87 Q96RW7 2.26e-34 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 10479 XM_044326841.1 18 5 59 9 87 Q96RW7 2.8e-34 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 10480 XM_044326841.1 18 5 59 9 87 Q96RW7 7.59e-34 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 10481 XM_044326841.1 18 5 59 9 87 Q96RW7 2.39e-33 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 10482 XM_044326841.1 18 5 59 9 87 Q96RW7 1.06e-32 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 10483 XM_044326841.1 18 5 59 9 87 Q96RW7 1.77e-31 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 10484 XM_044326841.1 18 5 59 9 87 Q96RW7 6.1e-31 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 10485 XM_044326841.1 18 5 59 9 87 Q96RW7 1.17e-28 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 10486 XM_044326841.1 18 5 59 9 87 Q96RW7 6.7e-25 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 10487 XM_044317608.1 327 37 276 48 893 NA NA NA NA NA NA 10488 XM_044326769.1 0 0 11 0 10 NA NA NA NA NA NA 10489 XM_029336914.2 1126 698 0 814 981 Q765P7 7.13e-59 Protein MTSS 2 (Actin-bundling with BAIAP2 homology protein 1) (ABBA-1) (MTSS1-like protein) Homo sapiens (Human) activation of GTPase activity [GO:0090630]; cell projection assembly [GO:0030031]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; lamellipodium organization [GO:0097581]; membrane organization [GO:0061024]; plasma membrane organization [GO:0007009] GO:0003779; GO:0003785; GO:0005096; GO:0005543; GO:0005546; GO:0007009; GO:0009898; GO:0015629; GO:0030027; GO:0030031; GO:0030864; GO:0031267; GO:0032587; GO:0036120; GO:0061024; GO:0090630; GO:0097581 10490 XM_044323773.1 405 1117 319 1278 533 NA NA NA NA NA NA 10491 XM_044321178.1 282 192 69 79 208 Q80XJ3 2.55e-83 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 10492 XM_044321178.1 282 192 69 79 208 Q80XJ3 1.01e-79 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 10493 XM_044321178.1 282 192 69 79 208 Q80XJ3 1.21e-79 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 10494 XM_044321178.1 282 192 69 79 208 Q80XJ3 7.4e-79 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 10495 XM_044321178.1 282 192 69 79 208 Q80XJ3 3.03e-78 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 10496 XM_044321178.1 282 192 69 79 208 Q80XJ3 1.22e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 10497 XM_044321178.1 282 192 69 79 208 Q80XJ3 1.11e-71 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 10498 XM_044321178.1 282 192 69 79 208 Q80XJ3 2.52e-68 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 10499 XM_044321178.1 282 192 69 79 208 Q80XJ3 2.26e-65 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 10500 XM_044321178.1 282 192 69 79 208 Q80XJ3 3.64e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 10501 XM_029353946.2 460 99 179 209 394 Q96RR1 3.3e-173 Twinkle mtDNA helicase (EC 3.6.4.12) (Progressive external ophthalmoplegia 1 protein) (T7 gp4-like protein with intramitochondrial nucleoid localization) (T7-like mitochondrial DNA helicase) (Twinkle protein, mitochondrial) Homo sapiens (Human) cellular response to glucose stimulus [GO:0071333]; DNA unwinding involved in DNA replication [GO:0006268]; mitochondrial DNA replication [GO:0006264]; mitochondrial transcription [GO:0006390]; protein hexamerization [GO:0034214] GO:0002020; GO:0003678; GO:0003697; GO:0005524; GO:0005739; GO:0005759; GO:0006264; GO:0006268; GO:0006390; GO:0016887; GO:0034214; GO:0042645; GO:0042802; GO:0043139; GO:0071333 10502 XM_029348587.2 567 905 226 906 733 P24369 2.85e-75 Peptidyl-prolyl cis-trans isomerase B (PPIase B) (EC 5.2.1.8) (CYP-S1) (Cyclophilin B) (Rotamase B) (S-cyclophilin) (SCYLP) Mus musculus (Mouse) bone development [GO:0060348]; chaperone-mediated protein folding [GO:0061077]; neutrophil chemotaxis [GO:0030593]; positive regulation by host of viral genome replication [GO:0044829]; positive regulation by host of viral process [GO:0044794]; positive regulation of multicellular organism growth [GO:0040018]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821] GO:0000413; GO:0003755; GO:0005654; GO:0005737; GO:0005783; GO:0005788; GO:0005790; GO:0006457; GO:0016018; GO:0030593; GO:0032991; GO:0034663; GO:0040018; GO:0042470; GO:0043231; GO:0044794; GO:0044829; GO:0048471; GO:0050821; GO:0060348; GO:0061077; GO:0070063 10503 XM_044315435.1 198 87 279 243 374 Q8D3M4 9.41e-79 2-aminoethylphosphonate--pyruvate transaminase (EC 2.6.1.37) (2-aminoethylphosphonate aminotransferase) (AEP transaminase) (AEPT) Vibrio vulnificus (strain CMCP6) organic phosphonate catabolic process [GO:0019700] GO:0019700; GO:0047304 10504 XM_044311792.1 124 0 0 0 0 NA NA NA NA NA NA 10505 XM_029357641.2 450 162 162 107 318 NA NA NA NA NA NA 10506 XM_044325468.1 4 38 2 67 64 Q8BR76 3.44e-26 Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67) Mus musculus (Mouse) branching morphogenesis of an epithelial tube [GO:0048754]; cilium assembly [GO:0060271]; determination of left/right symmetry [GO:0007368]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; head development [GO:0060322]; heart development [GO:0007507]; kidney development [GO:0001822]; negative regulation of centrosome duplication [GO:0010826]; non-canonical Wnt signaling pathway [GO:0035567]; photoreceptor cell outer segment organization [GO:0035845]; positive regulation of ERAD pathway [GO:1904294]; positive regulation of non-motile cilium assembly [GO:1902857]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0001822; GO:0005789; GO:0005813; GO:0005886; GO:0005929; GO:0005930; GO:0007368; GO:0007507; GO:0010826; GO:0030433; GO:0030659; GO:0031005; GO:0035567; GO:0035845; GO:0035869; GO:0036038; GO:0048754; GO:0051082; GO:0051787; GO:0060170; GO:0060271; GO:0060322; GO:0060441; GO:1902857; GO:1904294 10507 XR_006392511.1 8 0 0 22 0 NA NA NA NA NA NA 10508 XR_006397102.1 14 6 12 14 61 NA NA NA NA NA NA 10509 XM_029326582.2 3116 1104 1323 1099 724 A0A2B4RP11 1.63e-141 NA NA NA NA 10510 XM_044306828.1 172 13 295 17 0 Q3B8R1 2.01e-78 Endoplasmic reticulum membrane-associated RNA degradation protein (ER membrane-associated RNA degradation protein) Rattus norvegicus (Rat) NA GO:0005789 10511 XM_044324839.1 701 92 904 117 5280 Q6LAF1 6.34e-45 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 10512 XM_044328791.1 0 21 5 2 7 NA NA NA NA NA NA 10513 XR_006397760.1 20 0 21 129 36 NA NA NA NA NA NA 10514 XM_029350217.2 235 70 0 334 13 Q9R0Z9 9.13e-161 Rho GTPase-activating protein 7 (Deleted in liver cancer 1 protein homolog) (DLC-1) (Rho-type GTPase-activating protein 7) (START domain-containing protein 12) (StARD12) (StAR-related lipid transfer protein 12) Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of phospholipase C activity [GO:0007202]; apoptotic process [GO:0006915]; cytoskeleton organization [GO:0007010]; focal adhesion assembly [GO:0048041]; forebrain development [GO:0030900]; heart morphogenesis [GO:0003007]; hindbrain morphogenesis [GO:0021575]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of stress fiber assembly [GO:0051497]; neural tube closure [GO:0001843]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; regulation of Rho protein signal transduction [GO:0035023]; signal transduction [GO:0007165] GO:0001725; GO:0001843; GO:0003007; GO:0005096; GO:0005634; GO:0005737; GO:0005829; GO:0005884; GO:0005901; GO:0005925; GO:0006915; GO:0006919; GO:0007010; GO:0007165; GO:0007202; GO:0008285; GO:0008289; GO:0008360; GO:0017166; GO:0021575; GO:0030036; GO:0030336; GO:0030864; GO:0030900; GO:0032587; GO:0032956; GO:0035023; GO:0035024; GO:0035307; GO:0042169; GO:0043274; GO:0045121; GO:0048041; GO:0051497; GO:0051895; GO:1900119 10515 XM_029350217.2 235 70 0 334 13 Q9R0Z9 5.05e-24 Rho GTPase-activating protein 7 (Deleted in liver cancer 1 protein homolog) (DLC-1) (Rho-type GTPase-activating protein 7) (START domain-containing protein 12) (StARD12) (StAR-related lipid transfer protein 12) Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of phospholipase C activity [GO:0007202]; apoptotic process [GO:0006915]; cytoskeleton organization [GO:0007010]; focal adhesion assembly [GO:0048041]; forebrain development [GO:0030900]; heart morphogenesis [GO:0003007]; hindbrain morphogenesis [GO:0021575]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of stress fiber assembly [GO:0051497]; neural tube closure [GO:0001843]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; regulation of Rho protein signal transduction [GO:0035023]; signal transduction [GO:0007165] GO:0001725; GO:0001843; GO:0003007; GO:0005096; GO:0005634; GO:0005737; GO:0005829; GO:0005884; GO:0005901; GO:0005925; GO:0006915; GO:0006919; GO:0007010; GO:0007165; GO:0007202; GO:0008285; GO:0008289; GO:0008360; GO:0017166; GO:0021575; GO:0030036; GO:0030336; GO:0030864; GO:0030900; GO:0032587; GO:0032956; GO:0035023; GO:0035024; GO:0035307; GO:0042169; GO:0043274; GO:0045121; GO:0048041; GO:0051497; GO:0051895; GO:1900119 10516 XM_029332414.2 55 15 1 31 10 NA NA NA NA NA NA 10517 XM_029329949.2 96 598 466 75 129 Q16445 5.72e-58 Gamma-aminobutyric acid receptor subunit alpha-6 (GABA(A) receptor subunit alpha-6) Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid signaling pathway [GO:0007214]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; regulation of postsynaptic membrane potential [GO:0060078]; signal transduction [GO:0007165]; synaptic transmission, GABAergic [GO:0051932] GO:0004890; GO:0005231; GO:0005237; GO:0005886; GO:0007165; GO:0007214; GO:0007268; GO:0008503; GO:0022851; GO:0030594; GO:0032590; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051932; GO:0060078; GO:0098794; GO:0099192; GO:1902476; GO:1902711; GO:1904315 10518 XM_029340412.2 14 0 0 12 11 Q6IPR3 9.59e-44 tRNA wybutosine-synthesizing protein 3 homolog (tRNA-yW-synthesizing protein 3) (EC 2.1.1.282) (tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase) Homo sapiens (Human) tRNA methylation [GO:0030488] GO:0005737; GO:0008175; GO:0030488 10519 XM_044315451.1 45 27 71 224 63 NA NA NA NA NA NA 10520 XR_006397777.1 14 4 3 44 3 NA NA NA NA NA NA 10521 XM_044308459.1 0 162 0 193 58 NA NA NA NA NA NA 10522 XM_044329044.1 24 5 7 1 8 NA NA NA NA NA NA 10523 XM_029342272.2 407 281 583 361 487 Q98TB4 1.3e-31 Growth/differentiation factor 8 (Myostatin) (MSTN) Oreochromis mossambicus (Mozambique tilapia) (Tilapia mossambica) NA GO:0005125; GO:0005615; GO:0008083 10524 XR_006396574.1 1002 638 295 526 603 Q9NYR8 9.94e-72 Retinol dehydrogenase 8 (EC 1.1.1.300) (Photoreceptor outer segment all-trans retinol dehydrogenase) (Short chain dehydrogenase/reductase family 28C member 2) Homo sapiens (Human) estrogen biosynthetic process [GO:0006703]; response to stimulus [GO:0050896]; retinol metabolic process [GO:0042572]; steroid biosynthetic process [GO:0006694]; visual perception [GO:0007601] GO:0004303; GO:0004745; GO:0005829; GO:0005886; GO:0006694; GO:0006703; GO:0007601; GO:0016491; GO:0042572; GO:0050896; GO:0052650 10525 XR_006396574.1 1002 638 295 526 603 Q9NYR8 1.81e-30 Retinol dehydrogenase 8 (EC 1.1.1.300) (Photoreceptor outer segment all-trans retinol dehydrogenase) (Short chain dehydrogenase/reductase family 28C member 2) Homo sapiens (Human) estrogen biosynthetic process [GO:0006703]; response to stimulus [GO:0050896]; retinol metabolic process [GO:0042572]; steroid biosynthetic process [GO:0006694]; visual perception [GO:0007601] GO:0004303; GO:0004745; GO:0005829; GO:0005886; GO:0006694; GO:0006703; GO:0007601; GO:0016491; GO:0042572; GO:0050896; GO:0052650 10526 XR_006396574.1 1002 638 295 526 603 Q9NYR8 1.81e-30 Retinol dehydrogenase 8 (EC 1.1.1.300) (Photoreceptor outer segment all-trans retinol dehydrogenase) (Short chain dehydrogenase/reductase family 28C member 2) Homo sapiens (Human) estrogen biosynthetic process [GO:0006703]; response to stimulus [GO:0050896]; retinol metabolic process [GO:0042572]; steroid biosynthetic process [GO:0006694]; visual perception [GO:0007601] GO:0004303; GO:0004745; GO:0005829; GO:0005886; GO:0006694; GO:0006703; GO:0007601; GO:0016491; GO:0042572; GO:0050896; GO:0052650 10527 XM_029347373.2 2431 1325 1314 2010 892 NA NA NA NA NA NA 10528 XM_044310484.1 566 142 199 482 381 NA NA NA NA NA NA 10529 XM_044327847.1 20 22 20 2 77 NA NA NA NA NA NA 10530 XM_029351105.2 332 0 137 232 481 NA NA NA NA NA NA 10531 XR_006397345.1 0 8 0 0 1 NA NA NA NA NA NA 10532 XM_029331610.2 919 863 656 951 758 Q5UE94 3.98e-121 TATA box-binding protein-like 2 (TBP-like 2) (TATA box-binding protein-related factor 3) (TBP-related factor 3) Xenopus laevis (African clawed frog) DNA-templated transcription [GO:0006351]; DNA-templated transcription initiation [GO:0006352]; embryo development ending in birth or egg hatching [GO:0009792]; gastrulation [GO:0007369]; transcription by RNA polymerase II [GO:0006366] GO:0003677; GO:0003700; GO:0005634; GO:0006351; GO:0006352; GO:0006366; GO:0007369; GO:0009792 10533 XM_029325828.2 1 0 8 0 12 NA NA NA NA NA NA 10534 XM_029352934.2 217 205 90 96 193 Q6NRW2 1.77e-31 Protein Spindly-B (Coiled-coil domain-containing protein 99-B) (Spindle apparatus coiled-coil domain-containing protein 1-B) Xenopus laevis (African clawed frog) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly checkpoint signaling [GO:0007094]; protein localization to kinetochore [GO:0034501] GO:0000132; GO:0000922; GO:0000940; GO:0005634; GO:0007080; GO:0007094; GO:0034501; GO:0043515; GO:0051301 10535 XM_029337893.2 14 1 2 6 16 NA NA NA NA NA NA 10536 XM_029332558.2 678 272 267 582 486 P42785 0 Lysosomal Pro-X carboxypeptidase (EC 3.4.16.2) (Angiotensinase C) (Lysosomal carboxypeptidase C) (Proline carboxypeptidase) (Prolylcarboxypeptidase) (PRCP) Homo sapiens (Human) angiogenesis involved in wound healing [GO:0060055]; energy homeostasis [GO:0097009]; glucose homeostasis [GO:0042593]; negative regulation of systemic arterial blood pressure [GO:0003085]; plasma kallikrein-kinin cascade [GO:0002353]; proteolysis [GO:0006508]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of reactive oxygen species metabolic process [GO:2000377]; regulation of thyroid hormone mediated signaling pathway [GO:0002155] GO:0002155; GO:0002353; GO:0003085; GO:0004185; GO:0005886; GO:0006508; GO:0008239; GO:0035577; GO:0042593; GO:0043231; GO:0043535; GO:0045178; GO:0060055; GO:0070062; GO:0097009; GO:0101003; GO:2000377 10537 XM_044325095.1 9 290 25 4 47 NA NA NA NA NA NA 10538 XM_044310777.1 41 37 48 15 0 NA NA NA NA NA NA 10539 XM_029347757.2 489 304 272 311 365 Q5REY7 1.3e-123 UBX domain-containing protein 7 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0016604; GO:0031625; GO:0034098; GO:0043130; GO:0061629 10540 XM_044313269.1 776 372 102 207 51 Q5ZMP6 0 AP-2 complex subunit mu (AP-2 mu chain) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (HA2 50 kDa subunit) (Mu2-adaptin) (Plasma membrane adaptor AP-2 50 kDa protein) Gallus gallus (Chicken) clathrin-dependent endocytosis [GO:0072583]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192] GO:0006886; GO:0006897; GO:0008289; GO:0016192; GO:0030122; GO:0031410; GO:0035615; GO:0072583 10541 XM_044309423.1 1735 230 358 3484 536 NA NA NA NA NA NA 10542 XM_029342953.2 0 0 7 0 4 Q94K49 2.4e-29 Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1 (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) epigenetic regulation of gene expression [GO:0040029] GO:0003682; GO:0004518; GO:0005634; GO:0035098; GO:0035102; GO:0040029; GO:0046872 10543 XM_044311036.1 22 14 18 14 75 NA NA NA NA NA NA 10544 XM_029349159.2 2120 2010 1520 1661 1478 Q1HQK0 1.34e-114 Adenylate kinase (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate kinase cytosolic and mitochondrial) (Adenylate monophosphate kinase) Aedes aegypti (Yellowfever mosquito) (Culex aegypti) ADP biosynthetic process [GO:0006172]; AMP metabolic process [GO:0046033]; ATP metabolic process [GO:0046034]; phosphorylation [GO:0016310] GO:0004017; GO:0005524; GO:0005758; GO:0005829; GO:0006172; GO:0016310; GO:0046033; GO:0046034 10545 XM_044322173.1 63 66 83 29 19 NA NA NA NA NA NA 10546 XM_029335216.2 254 335 238 0 257 Q61382 6.91e-35 TNF receptor-associated factor 4 (EC 2.3.2.27) (Cysteine-rich motif associated to RING and Traf domains protein 1) Mus musculus (Mouse) activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; innate immune response [GO:0045087]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein kinase activity [GO:0045860]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; respiratory gaseous exchange by respiratory system [GO:0007585]; respiratory tube development [GO:0030323] GO:0001650; GO:0005164; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0005923; GO:0006915; GO:0007250; GO:0007585; GO:0008270; GO:0016740; GO:0019901; GO:0030323; GO:0031625; GO:0031996; GO:0042802; GO:0042981; GO:0043122; GO:0043161; GO:0045087; GO:0045860; GO:0046330; GO:0048471; GO:0050699 10547 XM_029346373.2 498 395 237 647 499 Q5FYB0 2.1e-133 Arylsulfatase J (ASJ) (EC 3.1.6.-) Homo sapiens (Human) NA GO:0004065; GO:0005576; GO:0005788; GO:0015629; GO:0046872 10548 XM_044326480.1 7709 7652 3550 8286 5875 NA NA NA NA NA NA 10549 XR_006397661.1 147 339 92 173 269 NA NA NA NA NA NA 10550 XM_044323411.1 2 0 14 0 10 NA NA NA NA NA NA 10551 XM_029324038.2 0 26 3 8 0 Q99807 1.08e-55 5-demethoxyubiquinone hydroxylase, mitochondrial (DMQ hydroxylase) (EC 1.14.99.60) (Timing protein clk-1 homolog) (Ubiquinone biosynthesis monooxygenase COQ7) Homo sapiens (Human) determination of adult lifespan [GO:0008340]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression [GO:0010468]; regulation of reactive oxygen species metabolic process [GO:2000377]; ubiquinone biosynthetic process [GO:0006744] GO:0000122; GO:0003682; GO:0005634; GO:0005694; GO:0005739; GO:0005743; GO:0006744; GO:0008340; GO:0008682; GO:0010468; GO:0016709; GO:0031314; GO:0045944; GO:0046872; GO:0110142; GO:2000377 10552 XR_006395663.1 259 590 181 357 391 Q6NRK8 1.25e-29 Protein THEM6 Xenopus laevis (African clawed frog) NA GO:0005576 10553 XM_029340477.2 174 120 101 208 130 Q6P0D7 8.06e-96 MAGUK p55 subfamily member 7 (Protein humpback) Danio rerio (Zebrafish) (Brachydanio rerio) protein localization to adherens junction [GO:0071896] GO:0005886; GO:0005911; GO:0005912; GO:0005923; GO:0071896 10554 XM_029344615.2 3624 4102 2857 5128 3160 NA NA NA NA NA NA 10555 XM_029335780.2 7 5 13 10 5 NA NA NA NA NA NA 10556 XM_044306973.1 0 0 27 0 0 A6PWV5 3.01e-67 AT-rich interactive domain-containing protein 3C (ARID domain-containing protein 3C) Mus musculus (Mouse) positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0003677; GO:0003682; GO:0005634; GO:0005737; GO:0006357; GO:0045121; GO:0045944 10557 XM_044313095.1 0 155 0 0 0 NA NA NA NA NA NA 10558 XM_044324705.1 3 63 18 32 41 Q9VBW3 5.97e-86 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 10559 XM_029325229.2 0 0 0 0 7 NA NA NA NA NA NA 10560 XR_006394600.1 0 45 5 32 0 NA NA NA NA NA NA 10561 XM_044326111.1 0 0 1 0 13 P47970 2.39e-36 Neuronal pentraxin-2 (NP2) (Acrosomal pentaxin-like protein p50) (AM50) (Neuronal pentraxin II) (Apexin) (NP-II) Cavia porcellus (Guinea pig) NA GO:0043160; GO:0046872 10562 XM_044310362.1 33 27 9 32 66 G3V9H8 6.52e-71 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Rattus norvegicus (Rat) cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0007156; GO:0007158; GO:0007169; GO:0007399; GO:0009410; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030182; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0098797 10563 XM_029346219.2 511 532 353 525 565 Q3T178 2.69e-107 Vacuolar protein sorting-associated protein 28 homolog (ESCRT-I complex subunit VPS28) Bos taurus (Bovine) negative regulation of protein ubiquitination [GO:0031397]; protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] GO:0000813; GO:0005737; GO:0005886; GO:0031397; GO:0031902; GO:0043162; GO:0043328; GO:0044877 10564 XM_044313349.1 5 0 12 2 2 NA NA NA NA NA NA 10565 XM_044313527.1 18 80 64 9 55 A0A0C2SRU0 9.8e-79 Decarboxylase iboD (EC 4.1.1.-) (Ibotenic acid biosynthesis cluster protein D) Amanita muscaria (strain Koide BX008) phospholipid biosynthetic process [GO:0008654] GO:0004609; GO:0008654 10566 XM_044321692.1 288 251 0 790 180 Q63415 9.49e-112 Proprotein convertase subtilisin/kexin type 6 (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin-like proprotein convertase 4) (SPC4) (Subtilisin/kexin-like protease PACE4) Rattus norvegicus (Rat) determination of left/right symmetry [GO:0007368]; glycoprotein metabolic process [GO:0009100]; nerve growth factor production [GO:0032902]; peptide hormone processing [GO:0016486]; protein processing [GO:0016485]; secretion by cell [GO:0032940]; zygotic determination of anterior/posterior axis, embryo [GO:0007354] GO:0004175; GO:0004252; GO:0005615; GO:0007354; GO:0007368; GO:0008201; GO:0009100; GO:0009986; GO:0016020; GO:0016485; GO:0016486; GO:0032902; GO:0032940; GO:0048406; GO:0062023 10567 XM_044312906.1 130 87 13 55 24 P59046 1.76e-51 NACHT, LRR and PYD domains-containing protein 12 (Monarch-1) (PYRIN-containing APAF1-like protein 7) (Regulated by nitric oxide) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cellular response to cytokine stimulus [GO:0071345]; dendritic cell migration [GO:0036336]; ERK1 and ERK2 cascade [GO:0070371]; negative regulation of cytokine production [GO:0001818]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of signal transduction [GO:0009968]; negative regulation of Toll signaling pathway [GO:0045751]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of inflammatory response [GO:0050727]; regulation of interleukin-18 production [GO:0032661]; signal transduction [GO:0007165] GO:0001818; GO:0005524; GO:0005737; GO:0005829; GO:0006919; GO:0007165; GO:0008656; GO:0009968; GO:0031953; GO:0032088; GO:0032661; GO:0032692; GO:0032715; GO:0032731; GO:0036336; GO:0038061; GO:0043122; GO:0043124; GO:0043281; GO:0045345; GO:0045751; GO:0050727; GO:0050728; GO:0050729; GO:0070371; GO:0070373; GO:0071345; GO:1901223; GO:1901224 10568 XM_044312906.1 130 87 13 55 24 P59046 4.53e-28 NACHT, LRR and PYD domains-containing protein 12 (Monarch-1) (PYRIN-containing APAF1-like protein 7) (Regulated by nitric oxide) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cellular response to cytokine stimulus [GO:0071345]; dendritic cell migration [GO:0036336]; ERK1 and ERK2 cascade [GO:0070371]; negative regulation of cytokine production [GO:0001818]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of signal transduction [GO:0009968]; negative regulation of Toll signaling pathway [GO:0045751]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of inflammatory response [GO:0050727]; regulation of interleukin-18 production [GO:0032661]; signal transduction [GO:0007165] GO:0001818; GO:0005524; GO:0005737; GO:0005829; GO:0006919; GO:0007165; GO:0008656; GO:0009968; GO:0031953; GO:0032088; GO:0032661; GO:0032692; GO:0032715; GO:0032731; GO:0036336; GO:0038061; GO:0043122; GO:0043124; GO:0043281; GO:0045345; GO:0045751; GO:0050727; GO:0050728; GO:0050729; GO:0070371; GO:0070373; GO:0071345; GO:1901223; GO:1901224 10569 XM_044325453.1 98 87 39 122 53 P19217 2.68e-53 Sulfotransferase 1E1 (ST1E1) (EC 2.8.2.4) (Estrogen sulfotransferase) (Sulfotransferase, estrogen-preferring) Bos taurus (Bovine) estrogen metabolic process [GO:0008210]; sulfation [GO:0051923] GO:0004062; GO:0004304; GO:0005496; GO:0005737; GO:0005829; GO:0008146; GO:0008210; GO:0050294; GO:0051923 10570 XM_044317710.1 87 0 61 0 331 NA NA NA NA NA NA 10571 XM_044320227.1 2320 381 1511 2990 4189 NA NA NA NA NA NA 10572 XM_044327200.1 641 463 607 612 716 P27653 0 C-1-tetrahydrofolate synthase, cytoplasmic (C1-THF synthase) [Includes: Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9); Formyltetrahydrofolate synthetase (EC 6.3.4.3)] Rattus norvegicus (Rat) 10-formyltetrahydrofolate biosynthetic process [GO:0009257]; heart development [GO:0007507]; histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; methionine metabolic process [GO:0006555]; neural tube closure [GO:0001843]; neutrophil homeostasis [GO:0001780]; nucleotide metabolic process [GO:0009117]; one-carbon metabolic process [GO:0006730]; purine nucleotide biosynthetic process [GO:0006164]; purine ribonucleotide biosynthetic process [GO:0009152]; response to nitrogen dioxide [GO:0035713]; serine family amino acid biosynthetic process [GO:0009070]; serine family amino acid metabolic process [GO:0009069]; somite development [GO:0061053]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653]; transsulfuration [GO:0019346] GO:0000105; GO:0001780; GO:0001843; GO:0004329; GO:0004477; GO:0004486; GO:0004487; GO:0004488; GO:0005524; GO:0005737; GO:0005829; GO:0006164; GO:0006555; GO:0006730; GO:0007507; GO:0009069; GO:0009070; GO:0009086; GO:0009117; GO:0009152; GO:0009257; GO:0019346; GO:0035713; GO:0035999; GO:0046653; GO:0061053 10573 XM_029330006.2 0 3 0 13 24 Q9TTT5 7.77e-88 Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3) Oryctolagus cuniculus (Rabbit) protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0008076; GO:0030425; GO:0034765; GO:0042383; GO:0046872; GO:0051260 10574 XM_029338416.2 3268 2064 1718 3224 2683 P26818 0 Beta-adrenergic receptor kinase 2 (Beta-ARK-2) (EC 2.7.11.15) (G-protein-coupled receptor kinase 3) Bos taurus (Bovine) desensitization of G protein-coupled receptor signaling pathway [GO:0002029]; G protein-coupled receptor signaling pathway [GO:0007186]; protein phosphorylation [GO:0006468]; receptor internalization [GO:0031623]; regulation of signal transduction [GO:0009966] GO:0001664; GO:0002029; GO:0004672; GO:0004703; GO:0005524; GO:0006468; GO:0007186; GO:0009966; GO:0031623; GO:0042995; GO:0047696; GO:0098793; GO:0098794 10575 XM_044319739.1 4 12 17 13 10 NA NA NA NA NA NA 10576 XM_029341004.2 21 319 168 175 515 Q8K078 2.05e-119 Solute carrier organic anion transporter family member 4A1 (Organic anion-transporting polypeptide E) (OATP-E) (Sodium-independent organic anion transporter E) (Solute carrier family 21 member 12) Mus musculus (Mouse) sodium-independent organic anion transport [GO:0043252]; thyroid hormone metabolic process [GO:0042403] GO:0005886; GO:0008514; GO:0015132; GO:0015347; GO:0015349; GO:0042403; GO:0043252 10577 XM_044321790.1 0 0 193 554 385 Q66JY2 4.34e-39 INO80 complex subunit D Mus musculus (Mouse) chromatin remodeling [GO:0006338]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of telomere maintenance in response to DNA damage [GO:1904507]; regulation of cell cycle [GO:0051726]; regulation of chromosome organization [GO:0033044]; regulation of DNA repair [GO:0006282]; regulation of DNA replication [GO:0006275]; regulation of DNA strand elongation [GO:0060382]; regulation of embryonic development [GO:0045995]; telomere maintenance [GO:0000723] GO:0000723; GO:0005634; GO:0006275; GO:0006281; GO:0006282; GO:0006310; GO:0006338; GO:0031011; GO:0033044; GO:0045739; GO:0045893; GO:0045995; GO:0051726; GO:0060382; GO:1904507 10578 XM_029343584.2 208 307 99 102 158 NA NA NA NA NA NA 10579 XM_029351649.2 39 58 18 19 62 NA NA NA NA NA NA 10580 XM_029355014.2 15 4 0 1 18 NA NA NA NA NA NA 10581 XM_029330484.2 688 400 380 666 634 NA NA NA NA NA NA 10582 XM_029329329.2 31 16 34 74 57 NA NA NA NA NA NA 10583 XR_003827211.2 90 116 36 17 38 NA NA NA NA NA NA 10584 XM_044311761.1 33 38 23 8 31 B8VIU6 4.06e-42 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 10585 XM_044310842.1 0 0 4 6 18 O43854 2.18e-24 EGF-like repeat and discoidin I-like domain-containing protein 3 (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1) Homo sapiens (Human) cell adhesion [GO:0007155]; positive regulation of cell-substrate adhesion [GO:0010811] GO:0005178; GO:0005509; GO:0007155; GO:0010811; GO:0062023; GO:0070062; GO:1903561 10586 XM_044310842.1 0 0 4 6 18 O43854 7.44e-22 EGF-like repeat and discoidin I-like domain-containing protein 3 (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1) Homo sapiens (Human) cell adhesion [GO:0007155]; positive regulation of cell-substrate adhesion [GO:0010811] GO:0005178; GO:0005509; GO:0007155; GO:0010811; GO:0062023; GO:0070062; GO:1903561 10587 XM_029355159.2 1145 1089 652 1020 761 Q5ZMW3 6.44e-170 Apoptosis inhibitor 5 (API-5) Gallus gallus (Chicken) apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066] GO:0003723; GO:0005634; GO:0005737; GO:0006915; GO:0017134; GO:0043066 10588 XM_044318265.1 16 0 7 0 3 P31422 0 Metabotropic glutamate receptor 3 (mGluR3) Rattus norvegicus (Rat) G protein-coupled glutamate receptor signaling pathway [GO:0007216]; gene expression [GO:0010467]; modulation of chemical synaptic transmission [GO:0050804]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; regulation of synaptic transmission, glutamatergic [GO:0051966]; sensory perception of pain [GO:0019233] GO:0001640; GO:0001641; GO:0005246; GO:0005886; GO:0007216; GO:0010467; GO:0014069; GO:0019233; GO:0030424; GO:0042734; GO:0043005; GO:0043197; GO:0045211; GO:0050804; GO:0051966; GO:0097110; GO:0097449; GO:0098794; GO:0098978; GO:0099170 10589 XM_029333399.2 288 114 153 185 394 NA NA NA NA NA NA 10590 XR_003826187.2 504 404 221 464 766 NA NA NA NA NA NA 10591 XM_029355935.2 55 0 0 0 0 NA NA NA NA NA NA 10592 XM_029346131.2 2008 1309 1087 1842 1745 Q80U96 0 Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog) Rattus norvegicus (Rat) cellular response to salt [GO:1902075]; cellular response to triglyceride [GO:0071401]; mRNA transport [GO:0051028]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleocytoplasmic transport [GO:0006913]; protein export from nucleus [GO:0006611]; protein localization [GO:0008104]; protein localization to nucleus [GO:0034504]; regulation of centrosome duplication [GO:0010824]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]; regulation of protein catabolic process [GO:0042176]; regulation of protein export from nucleus [GO:0046825]; response to xenobiotic stimulus [GO:0009410]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; ribosomal subunit export from nucleus [GO:0000054]; ribosome biogenesis [GO:0042254] GO:0000054; GO:0000055; GO:0000056; GO:0000122; GO:0000776; GO:0003723; GO:0005049; GO:0005634; GO:0005642; GO:0005730; GO:0005737; GO:0006611; GO:0006913; GO:0008104; GO:0009410; GO:0010824; GO:0015030; GO:0019904; GO:0031267; GO:0032434; GO:0032991; GO:0034504; GO:0042176; GO:0042254; GO:0046825; GO:0051028; GO:0071401; GO:0140297; GO:1902075; GO:1990904 10593 XM_029331885.2 15 0 0 0 0 NA NA NA NA NA NA 10594 XM_044321185.1 12 9 11 7 35 F1PZV2 1.75e-31 Major facilitator superfamily domain-containing protein 12 Canis lupus familiaris (Dog) (Canis familiaris) carbohydrate transport [GO:0008643]; cysteine transmembrane transport [GO:1903712]; melanin biosynthetic process [GO:0042438]; organic substance transport [GO:0071702]; pigment metabolic process involved in pigmentation [GO:0043474]; regulation of melanin biosynthetic process [GO:0048021] GO:0005764; GO:0005765; GO:0005886; GO:0008643; GO:0015293; GO:0033162; GO:0033229; GO:0042438; GO:0043474; GO:0048021; GO:0071702; GO:1903712 10595 XM_044317730.1 5 0 5 2 64 NA NA NA NA NA NA 10596 XM_044325845.1 86 40 67 103 132 NA NA NA NA NA NA 10597 XR_006397079.1 55 11 11 79 11 NA NA NA NA NA NA 10598 XM_029330424.2 0 0 0 40 0 O43603 2.6e-28 Galanin receptor type 2 (GAL2-R) (GALR-2) Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell surface receptor signaling pathway [GO:0007166]; feeding behavior [GO:0007631]; galanin-activated signaling pathway [GO:0090663]; inositol phosphate metabolic process [GO:0043647]; learning or memory [GO:0007611]; muscle contraction [GO:0006936]; negative regulation of adenylate cyclase activity [GO:0007194]; neuron projection development [GO:0031175]; neuropeptide signaling pathway [GO:0007218]; phosphatidylinositol metabolic process [GO:0046488]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of large conductance calcium-activated potassium channel activity [GO:1902608]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0004966; GO:0005886; GO:0005929; GO:0006936; GO:0007166; GO:0007188; GO:0007189; GO:0007194; GO:0007200; GO:0007204; GO:0007218; GO:0007611; GO:0007631; GO:0008528; GO:0016020; GO:0017046; GO:0031175; GO:0042923; GO:0043647; GO:0045944; GO:0046488; GO:0090663; GO:1902608 10599 XM_029351633.2 198 132 106 264 331 NA NA NA NA NA NA 10600 XM_029331156.2 93 38 77 42 39 NA NA NA NA NA NA 10601 XR_006393244.1 39 48 110 17 33 NA NA NA NA NA NA 10602 XM_044314899.1 1480 423 374 1120 607 NA NA NA NA NA NA 10603 XR_006393769.1 0 0 0 0 10 NA NA NA NA NA NA 10604 XM_044316003.1 45 17 28 26 12 Q80XJ3 3.86e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 10605 XR_003825943.2 4 11 12 0 2 NA NA NA NA NA NA 10606 XR_006396047.1 56 100 77 262 111 Q7M3E1 4e-43 Chymotrypsin-C (EC 3.4.21.2) (bPTLP) Bos taurus (Bovine) proteolysis [GO:0006508] GO:0004252; GO:0005615; GO:0006508 10607 XM_029352142.1 155 330 428 653 441 Q9JJL4 3.66e-32 Rho-related GTP-binding protein RhoQ (Ras-like protein TC10) Rattus norvegicus (Rat) actin cytoskeleton organization [GO:0030036]; cellular response to insulin stimulus [GO:0032869]; cortical actin cytoskeleton organization [GO:0030866]; endocytosis [GO:0006897]; establishment or maintenance of cell polarity [GO:0007163]; GTP metabolic process [GO:0046039]; insulin receptor signaling pathway [GO:0008286]; negative regulation of protein localization to plasma membrane [GO:1903077]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of glucose import [GO:0046326]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; small GTPase mediated signal transduction [GO:0007264] GO:0003924; GO:0005522; GO:0005525; GO:0005737; GO:0005884; GO:0005886; GO:0006897; GO:0007163; GO:0007264; GO:0008286; GO:0008360; GO:0030036; GO:0030866; GO:0032427; GO:0032869; GO:0045121; GO:0045944; GO:0046039; GO:0046326; GO:0051491; GO:1903077 10608 XR_003823134.1 2 1 12 2 23 NA NA NA NA NA NA 10609 XM_029354016.2 5 4 0 30 28 Q9CYL5 2.55e-23 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Mus musculus (Mouse) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070374 10610 XM_029337945.2 16 44 41 219 146 NA NA NA NA NA NA 10611 XM_029349211.2 60 36 17 34 59 Q862Z3 2.05e-27 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Canis lupus familiaris (Dog) (Canis familiaris) antibacterial innate immune response [GO:0140367]; defense response to Gram-negative bacterium [GO:0050829]; neutrophil migration [GO:1990266] GO:0000922; GO:0005201; GO:0005509; GO:0005615; GO:0005929; GO:0009986; GO:0016020; GO:0016323; GO:0016324; GO:0050829; GO:0060170; GO:0140367; GO:1990266 10612 XM_044309095.1 219 82 157 9 284 Q14974 1.72e-94 Importin subunit beta-1 (Importin-90) (Karyopherin subunit beta-1) (Nuclear factor p97) (Pore targeting complex 97 kDa subunit) (PTAC97) Homo sapiens (Human) astral microtubule organization [GO:0030953]; establishment of mitotic spindle localization [GO:0040001]; establishment of protein localization [GO:0045184]; mitotic chromosome movement towards spindle pole [GO:0007079]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly [GO:0090307]; NLS-bearing protein import into nucleus [GO:0006607]; protein import into nucleus [GO:0006606]; Ran protein signal transduction [GO:0031291]; ribosomal protein import into nucleus [GO:0006610]; RNA import into nucleus [GO:0006404] GO:0003723; GO:0005576; GO:0005634; GO:0005635; GO:0005643; GO:0005654; GO:0005737; GO:0005829; GO:0006404; GO:0006606; GO:0006607; GO:0006610; GO:0007079; GO:0007080; GO:0008139; GO:0008270; GO:0010494; GO:0016020; GO:0019899; GO:0019904; GO:0030953; GO:0031267; GO:0031291; GO:0031965; GO:0035580; GO:0040001; GO:0042564; GO:0045184; GO:0051879; GO:0061608; GO:0061676; GO:0070062; GO:0071782; GO:0090307; GO:1904813 10613 XM_044307004.1 35 3 0 160 8 NA NA NA NA NA NA 10614 XM_029343432.2 1367 1243 690 1142 759 P52632 1.29e-109 Signal transducer and activator of transcription 5B Rattus norvegicus (Rat) activated T cell proliferation [GO:0050798]; acute-phase response [GO:0006953]; B cell differentiation [GO:0030183]; cell population proliferation [GO:0008283]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; cellular response to hormone stimulus [GO:0032870]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; development of secondary female sexual characteristics [GO:0046543]; development of secondary male sexual characteristics [GO:0046544]; erythrocyte differentiation [GO:0030218]; female pregnancy [GO:0007565]; gamma-delta T cell differentiation [GO:0042492]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; lactation [GO:0007595]; lipid storage [GO:0019915]; liver development [GO:0001889]; luteinization [GO:0001553]; lymphocyte differentiation [GO:0030098]; mast cell migration [GO:0097531]; mitotic cell cycle [GO:0000278]; myeloid cell apoptotic process [GO:0033028]; natural killer cell differentiation [GO:0001779]; natural killer cell mediated cytotoxicity [GO:0042267]; natural killer cell proliferation [GO:0001787]; negative regulation of apoptotic process [GO:0043066]; negative regulation of erythrocyte differentiation [GO:0045647]; negative regulation of myeloid cell apoptotic process [GO:0033033]; Peyer's patch development [GO:0048541]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of gamma-delta T cell differentiation [GO:0045588]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of lymphocyte differentiation [GO:0045621]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of natural killer cell differentiation [GO:0032825]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; progesterone metabolic process [GO:0042448]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of cell adhesion [GO:0030155]; regulation of cell population proliferation [GO:0042127]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell differentiation [GO:0030856]; regulation of multicellular organism growth [GO:0040014]; regulation of steroid metabolic process [GO:0019218]; regulation of transcription by RNA polymerase II [GO:0006357]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to interleukin-15 [GO:0070672]; response to interleukin-2 [GO:0070669]; response to interleukin-4 [GO:0070670]; response to lipopolysaccharide [GO:0032496]; response to peptide hormone [GO:0043434]; sex differentiation [GO:0007548]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; taurine metabolic process [GO:0019530]; transcription by RNA polymerase II [GO:0006366] GO:0000278; GO:0000978; GO:0000981; GO:0001228; GO:0001553; GO:0001666; GO:0001779; GO:0001787; GO:0001889; GO:0003677; GO:0003682; GO:0003690; GO:0003700; GO:0005634; GO:0005737; GO:0005829; GO:0006355; GO:0006357; GO:0006366; GO:0006952; GO:0006953; GO:0007259; GO:0007548; GO:0007565; GO:0007595; GO:0008283; GO:0008284; GO:0010628; GO:0014911; GO:0019218; GO:0019221; GO:0019530; GO:0019915; GO:0030098; GO:0030155; GO:0030183; GO:0030218; GO:0030856; GO:0032355; GO:0032496; GO:0032743; GO:0032819; GO:0032825; GO:0032870; GO:0033028; GO:0033033; GO:0033077; GO:0035259; GO:0040014; GO:0040018; GO:0042104; GO:0042127; GO:0042267; GO:0042448; GO:0042492; GO:0042802; GO:0042803; GO:0043029; GO:0043066; GO:0043434; GO:0043565; GO:0045471; GO:0045579; GO:0045588; GO:0045621; GO:0045647; GO:0045648; GO:0045931; GO:0045944; GO:0045954; GO:0046543; GO:0046544; GO:0046983; GO:0048541; GO:0048661; GO:0050729; GO:0050798; GO:0060397; GO:0070669; GO:0070670; GO:0070672; GO:0071363; GO:0071364; GO:0090271; GO:0097531; GO:0140297 10615 XM_044309942.1 269 27 16 297 297 P18433 6.72e-133 Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (EC 3.1.3.48) Homo sapiens (Human) insulin receptor signaling pathway [GO:0008286]; integrin-mediated signaling pathway [GO:0007229]; modulation of chemical synaptic transmission [GO:0050804]; protein dephosphorylation [GO:0006470]; protein phosphorylation [GO:0006468]; regulation of focal adhesion assembly [GO:0051893] GO:0004725; GO:0005001; GO:0005886; GO:0005925; GO:0006468; GO:0006470; GO:0007229; GO:0008286; GO:0016020; GO:0043235; GO:0050804; GO:0051893; GO:0070062; GO:0097060; GO:0098685 10616 XM_044322040.1 1153 746 543 885 1005 NA NA NA NA NA NA 10617 XM_029345864.2 27 84 79 159 19 Q8UW76 1.41e-102 T-box transcription factor TBX20 (T-box protein 20) (cTbx20) Gallus gallus (Chicken) aortic valve morphogenesis [GO:0003180]; atrial septum morphogenesis [GO:0060413]; atrioventricular canal development [GO:0036302]; blood circulation [GO:0008015]; branching involved in blood vessel morphogenesis [GO:0001569]; cardiac chamber formation [GO:0003207]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac right ventricle morphogenesis [GO:0003215]; cell fate specification [GO:0001708]; cell migration involved in heart development [GO:0060973]; cell proliferation involved in heart valve development [GO:2000793]; dorsal/ventral pattern formation [GO:0009953]; embryonic heart tube elongation [GO:0036306]; endocardial cushion formation [GO:0003272]; foramen ovale closure [GO:0035922]; heart looping [GO:0001947]; mesenchymal cell development [GO:0014031]; motor neuron migration [GO:0097475]; muscle contraction [GO:0006936]; negative regulation of gene expression [GO:0010629]; negative regulation of SMAD protein complex assembly [GO:0010991]; negative regulation of transcription by RNA polymerase II [GO:0000122]; outflow tract septum morphogenesis [GO:0003148]; pericardium morphogenesis [GO:0003344]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell migration [GO:0030335]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of gene expression [GO:0010628]; pulmonary valve formation [GO:0003193]; pulmonary vein morphogenesis [GO:0060577]; regulation of transcription by RNA polymerase II [GO:0006357]; tricuspid valve development [GO:0003175]; vasculogenesis [GO:0001570]; visceral motor neuron differentiation [GO:0021524] GO:0000122; GO:0000978; GO:0000981; GO:0001228; GO:0001569; GO:0001570; GO:0001708; GO:0001947; GO:0003148; GO:0003175; GO:0003180; GO:0003193; GO:0003207; GO:0003215; GO:0003272; GO:0003344; GO:0005634; GO:0005737; GO:0006357; GO:0006936; GO:0008015; GO:0009953; GO:0010628; GO:0010629; GO:0010718; GO:0010991; GO:0014031; GO:0021524; GO:0030335; GO:0030513; GO:0035922; GO:0036302; GO:0036306; GO:0055008; GO:0060045; GO:0060413; GO:0060577; GO:0060973; GO:0061629; GO:0097475; GO:2000793 10618 XM_029335557.2 1705 1133 1000 1227 1782 A6QP70 6.41e-31 Beta-sarcoglycan (Beta-SG) Bos taurus (Bovine) muscle organ development [GO:0007517] GO:0005737; GO:0005856; GO:0007517; GO:0016012; GO:0042383 10619 XM_044310762.1 16 5 5 0 15 NA NA NA NA NA NA 10620 XM_029334523.2 74 152 56 230 141 NA NA NA NA NA NA 10621 XM_044313492.1 0 0 0 9 0 NA NA NA NA NA NA 10622 XM_044319751.1 86 190 9 98 43 A5D9C6 9.28e-80 Repressor of RNA polymerase III transcription MAF1 homolog Bos taurus (Bovine) negative regulation of transcription by RNA polymerase III [GO:0016480] GO:0000994; GO:0005634; GO:0005737; GO:0016480 10623 XM_044324049.1 0 46 0 0 5 NA NA NA NA NA NA 10624 XM_044313445.1 0 0 3 4 24 NA NA NA NA NA NA 10625 XM_044315215.1 89 46 55 29 9 NA NA NA NA NA NA 10626 XM_044317660.1 7 3 14 0 9 NA NA NA NA NA NA 10627 XM_029335685.2 250 143 131 170 279 Q6BZW3 7.47e-32 Protein BTN1 Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica) L-arginine transmembrane transport [GO:1903826]; lysine transport [GO:0015819]; regulation of intracellular pH [GO:0051453] GO:0000324; GO:0005773; GO:0005774; GO:0015819; GO:0022857; GO:0051453; GO:1903826 10628 XM_029345560.2 939 1423 810 1289 3009 NA NA NA NA NA NA 10629 XM_029328059.2 2 0 2 128 14 NA NA NA NA NA NA 10630 XM_029340244.2 1624 1020 718 1344 1132 O15084 0 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A (PP6-ARS-A) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-A) (Ankyrin repeat domain-containing protein 28) (Phosphatase interactor targeting protein hnRNP K) (PITK) Homo sapiens (Human) NA GO:0005654; GO:0005829 10631 XR_006397737.1 110 58 84 147 130 NA NA NA NA NA NA 10632 XM_044314360.1 476 398 64 312 128 Q6ZUG5 9.83e-99 Uncharacterized protein FLJ43738 Homo sapiens (Human) NA NA 10633 XM_044307934.1 57 59 32 50 135 NA NA NA NA NA NA 10634 XM_044327920.1 34 95 144 1 120 P21956 1.76e-49 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (SED1) (Sperm surface protein SP47) (MP47) Mus musculus (Mouse) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0007155; GO:0007338; GO:0009897; GO:0043277; GO:0062023 10635 XM_044324362.1 25 274 46 629 317 NA NA NA NA NA NA 10636 XM_029341892.2 4597 6473 2679 7873 6543 Q02156 0 Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon) Homo sapiens (Human) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell-substrate adhesion [GO:0031589]; cellular response to ethanol [GO:0071361]; cellular response to hypoxia [GO:0071456]; cellular response to prostaglandin E stimulus [GO:0071380]; establishment of localization in cell [GO:0051649]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; insulin secretion [GO:0030073]; intracellular signal transduction [GO:0035556]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; locomotory exploration behavior [GO:0035641]; macrophage activation involved in immune response [GO:0002281]; MAPK cascade [GO:0000165]; mucus secretion [GO:0070254]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of sodium ion transmembrane transporter activity [GO:2000650]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of cellular glucuronidation [GO:2001031]; positive regulation of cytokinesis [GO:0032467]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of insulin secretion [GO:0032024]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mucus secretion [GO:0070257]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; response to morphine [GO:0043278]; signal transduction [GO:0007165]; synaptic transmission, GABAergic [GO:0051932]; TRAM-dependent toll-like receptor 4 signaling pathway [GO:0035669] GO:0000165; GO:0002281; GO:0003785; GO:0004672; GO:0004674; GO:0004697; GO:0004698; GO:0004699; GO:0005524; GO:0005634; GO:0005737; GO:0005739; GO:0005783; GO:0005794; GO:0005829; GO:0005886; GO:0006468; GO:0006915; GO:0007049; GO:0007165; GO:0008047; GO:0010634; GO:0010763; GO:0010811; GO:0018105; GO:0019899; GO:0030073; GO:0030546; GO:0030838; GO:0031397; GO:0031589; GO:0031663; GO:0032024; GO:0032230; GO:0032467; GO:0035276; GO:0035556; GO:0035641; GO:0035669; GO:0038096; GO:0043123; GO:0043231; GO:0043278; GO:0043410; GO:0045111; GO:0045202; GO:0046872; GO:0048471; GO:0050730; GO:0050996; GO:0051279; GO:0051301; GO:0051649; GO:0051932; GO:0061178; GO:0070254; GO:0070257; GO:0071361; GO:0071380; GO:0071456; GO:0071889; GO:0071944; GO:0090303; GO:0106310; GO:1903078; GO:2000650; GO:2001031 10637 XM_029338164.2 405 222 166 259 256 NA NA NA NA NA NA 10638 XM_029349812.2 267 166 102 140 222 Q9C5L3 7.31e-23 Putative glycerol-3-phosphate transporter 1 (G-3-P transporter 1) (Glycerol-3-phosphate permease 1) (AtG3Pp1) (G-3-P permease 1) (Protein PHOSPHATE STARVATION-INDUCED GENE 3) (AtPS3) Arabidopsis thaliana (Mouse-ear cress) carbohydrate transport [GO:0008643]; phosphate ion homeostasis [GO:0055062] GO:0008643; GO:0016020; GO:0022857; GO:0055062 10639 XM_044309727.1 424 365 222 741 1111 Q32PN7 1.19e-30 Cilium assembly protein DZIP1L (DAZ-interacting zinc finger protein 1-like) Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; regulation of protein localization [GO:0032880] GO:0005737; GO:0005814; GO:0032880; GO:0036064; GO:0046872; GO:0060271 10640 XM_044308165.1 11 0 6 0 0 NA NA NA NA NA NA 10641 XM_044311367.1 35 0 16 0 3 NA NA NA NA NA NA 10642 XM_029347256.2 7 0 5 14 33 NA NA NA NA NA NA 10643 XM_029342679.2 292 190 151 220 344 P48053 8.12e-172 Uncharacterized protein C05D11.1 Caenorhabditis elegans NA GO:0004222; GO:0046872 10644 XM_029348988.2 420 388 253 535 527 A7RKF6 0 RNA-splicing ligase RtcB homolog (EC 6.5.1.8) (3'-phosphate/5'-hydroxy nucleic acid ligase) Nematostella vectensis (Starlet sea anemone) tRNA exon ligation utilizing 2',3' cyclic phosphate of 5'-exon as source of linkage phosphate [GO:0000971] GO:0000971; GO:0003972; GO:0005525; GO:0005634; GO:0046872; GO:0072669 10645 XM_029357529.2 113 89 67 150 299 P0C6B8 0 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 10646 XM_029357529.2 113 89 67 150 299 P0C6B8 3.32e-53 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 10647 XM_029357529.2 113 89 67 150 299 P0C6B8 1.01e-51 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 10648 XM_029357529.2 113 89 67 150 299 P0C6B8 1.03e-49 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 10649 XM_029357529.2 113 89 67 150 299 P0C6B8 5.51e-47 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 10650 XM_029357529.2 113 89 67 150 299 P0C6B8 2.23e-42 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 10651 XM_029357529.2 113 89 67 150 299 P0C6B8 6.14e-41 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 10652 XM_029357529.2 113 89 67 150 299 P0C6B8 2.92e-40 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 10653 XM_029357529.2 113 89 67 150 299 P0C6B8 2.77e-39 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 10654 XM_029357529.2 113 89 67 150 299 P0C6B8 3.79e-39 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 10655 XM_029357529.2 113 89 67 150 299 P0C6B8 1.52e-37 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 10656 XM_029357529.2 113 89 67 150 299 P0C6B8 2.18e-37 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 10657 XM_029357529.2 113 89 67 150 299 P0C6B8 4.48e-36 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 10658 XM_029357529.2 113 89 67 150 299 P0C6B8 1.65e-35 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 10659 XM_029357529.2 113 89 67 150 299 P0C6B8 2.13e-34 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 10660 XM_029357529.2 113 89 67 150 299 P0C6B8 4.24e-34 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 10661 XM_029357529.2 113 89 67 150 299 P0C6B8 4.41e-30 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 10662 XM_029354028.2 16 0 32 16 60 P42291 7.96e-23 D(1C) dopamine receptor Xenopus laevis (African clawed frog) regulation of biological quality [GO:0065008] GO:0004930; GO:0005886; GO:0065008 10663 XM_044308635.1 12 12 40 0 0 A7SP74 2.58e-22 Proteasome assembly chaperone 3 Nematostella vectensis (Starlet sea anemone) proteasome assembly [GO:0043248] GO:0043248 10664 XM_044318971.1 96 315 102 176 269 Q3ZCC3 2.56e-112 TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6) Bos taurus (Bovine) activation of NF-kappaB-inducing kinase activity [GO:0007250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; bone resorption [GO:0045453]; cellular response to DNA damage stimulus [GO:0006974]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; in utero embryonic development [GO:0001701]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-17-mediated signaling pathway [GO:0097400]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin production [GO:0002637]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000122; GO:0001503; GO:0001701; GO:0001843; GO:0002637; GO:0002726; GO:0004842; GO:0005164; GO:0005634; GO:0005811; GO:0005829; GO:0005938; GO:0006974; GO:0007249; GO:0007250; GO:0008270; GO:0009898; GO:0019886; GO:0030316; GO:0031435; GO:0031624; GO:0031625; GO:0031663; GO:0031666; GO:0031996; GO:0032735; GO:0032743; GO:0032755; GO:0032813; GO:0033209; GO:0035631; GO:0042088; GO:0042102; GO:0042475; GO:0042802; GO:0042826; GO:0042981; GO:0043011; GO:0043122; GO:0043123; GO:0043422; GO:0043507; GO:0045453; GO:0045672; GO:0045944; GO:0046330; GO:0047485; GO:0048471; GO:0050852; GO:0051092; GO:0051865; GO:0061630; GO:0070498; GO:0070534; GO:0097400; GO:1901224; GO:1904996; GO:2000679 10665 XM_044307749.1 144 45 67 58 218 F6R2G2 5.08e-24 NLR family CARD domain-containing protein 4 (Ice protease-activating factor) (Ipaf) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) apoptotic process [GO:0006915]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; regulation of apoptotic process [GO:0042981] GO:0005524; GO:0005829; GO:0006915; GO:0006954; GO:0042981; GO:0045087 10666 XR_006391872.1 136 98 115 271 245 NA NA NA NA NA NA 10667 XM_029329215.2 2097 2108 1962 2575 2716 Q15059 1.32e-102 Bromodomain-containing protein 3 (RING3-like protein) Homo sapiens (Human) chromatin remodeling [GO:0006338]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000785; GO:0003682; GO:0005634; GO:0006338; GO:0006355; GO:0006357; GO:0070577 10668 XM_029329215.2 2097 2108 1962 2575 2716 Q15059 2.12e-40 Bromodomain-containing protein 3 (RING3-like protein) Homo sapiens (Human) chromatin remodeling [GO:0006338]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000785; GO:0003682; GO:0005634; GO:0006338; GO:0006355; GO:0006357; GO:0070577 10669 XM_029329215.2 2097 2108 1962 2575 2716 Q15059 4.33e-26 Bromodomain-containing protein 3 (RING3-like protein) Homo sapiens (Human) chromatin remodeling [GO:0006338]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000785; GO:0003682; GO:0005634; GO:0006338; GO:0006355; GO:0006357; GO:0070577 10670 XR_006397016.1 108 107 106 98 189 NA NA NA NA NA NA 10671 XM_044313579.1 25 164 15 36 8 NA NA NA NA NA NA 10672 XM_029323575.2 78 6 65 55 167 NA NA NA NA NA NA 10673 XM_044323808.1 67 28 53 29 306 D3Z2X2 1.31e-69 Dynein heavy chain domain-containing protein 1 (Coiled-coil domain-containing protein 35) (Dynein heavy chain domain 1-like protein) Mus musculus (Mouse) cilium movement [GO:0003341]; flagellated sperm motility [GO:0030317]; microtubule-based movement [GO:0007018]; sperm flagellum assembly [GO:0120316] GO:0003341; GO:0005524; GO:0007018; GO:0008569; GO:0030286; GO:0030317; GO:0036126; GO:0036156; GO:0045505; GO:0051959; GO:0120316 10674 XM_044315002.1 880 1110 1115 676 1288 NA NA NA NA NA NA 10675 XM_029339503.2 17 0 0 9 0 NA NA NA NA NA NA 10676 XM_029330975.2 370 391 337 629 320 Q9R022 4.97e-29 DnaJ homolog subfamily C member 12 (J domain-containing protein 1) Mus musculus (Mouse) NA GO:0005737 10677 XM_044316813.1 14 60 0 171 249 NA NA NA NA NA NA 10678 XM_044317899.1 3910 5424 2102 3688 2444 Q6DC64 3.88e-119 RNA N6-adenosine-methyltransferase mettl16 (Methyltransferase 10 domain-containing protein) (Methyltransferase-like protein 16) (N6-adenosine-methyltransferase METTL16) (EC 2.1.1.348) (U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase) (EC 2.1.1.346) Danio rerio (Zebrafish) (Brachydanio rerio) mRNA catabolic process [GO:0006402]; mRNA destabilization [GO:0061157]; mRNA methylation [GO:0080009]; post-transcriptional regulation of gene expression [GO:0010608]; regulation of mRNA splicing, via spliceosome [GO:0048024]; rRNA base methylation [GO:0070475]; S-adenosylmethionine biosynthetic process [GO:0006556]; snRNA (adenine-N6)-methylation [GO:0120049] GO:0001734; GO:0003723; GO:0005634; GO:0005737; GO:0006402; GO:0006556; GO:0010608; GO:0030629; GO:0035613; GO:0048024; GO:0052907; GO:0061157; GO:0070475; GO:0080009; GO:0120048; GO:0120049 10679 XM_029324681.2 2395 1991 1184 1862 1927 Q9Y2U5 1.44e-139 Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2) Homo sapiens (Human) cellular response to mechanical stimulus [GO:0071260]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468] GO:0004672; GO:0004674; GO:0004709; GO:0005524; GO:0005654; GO:0005737; GO:0005829; GO:0006468; GO:0019901; GO:0035556; GO:0046872; GO:0071260; GO:0106310 10680 XM_044320344.1 2187 1218 1135 2073 724 P22607 3.38e-99 Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333) Homo sapiens (Human) bone maturation [GO:0070977]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cell-cell signaling [GO:0007267]; chondrocyte differentiation [GO:0002062]; chondrocyte proliferation [GO:0035988]; endochondral bone growth [GO:0003416]; endochondral ossification [GO:0001958]; fibroblast growth factor receptor apoptotic signaling pathway [GO:1902178]; fibroblast growth factor receptor signaling pathway [GO:0008543]; MAPK cascade [GO:0000165]; negative regulation of developmental growth [GO:0048640]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein autophosphorylation [GO:0046777]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0000165; GO:0001501; GO:0001958; GO:0002062; GO:0003416; GO:0004713; GO:0004714; GO:0005007; GO:0005524; GO:0005576; GO:0005634; GO:0005783; GO:0005794; GO:0005886; GO:0007169; GO:0007267; GO:0008284; GO:0008543; GO:0009986; GO:0010518; GO:0017134; GO:0018108; GO:0030133; GO:0030282; GO:0033674; GO:0035988; GO:0042531; GO:0042802; GO:0043235; GO:0043410; GO:0043552; GO:0046777; GO:0048640; GO:0060349; GO:0070374; GO:0070977; GO:1902178 10681 XM_029351893.2 169 137 46 268 169 NA NA NA NA NA NA 10682 XM_029357417.2 507 274 350 531 728 Q5HZJ0 0 Ribonuclease 3 (EC 3.1.26.3) (Protein Drosha) (Ribonuclease III) (RNase III) Mus musculus (Mouse) defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; miRNA metabolic process [GO:0010586]; positive regulation of gene expression [GO:0010628]; pre-miRNA processing [GO:0031054]; primary miRNA processing [GO:0031053]; regulation of gene expression [GO:0010468]; regulation of inflammatory response [GO:0050727]; regulation of miRNA metabolic process [GO:2000628]; regulation of regulatory T cell differentiation [GO:0045589]; RNA processing [GO:0006396]; rRNA processing [GO:0006364] GO:0001530; GO:0003725; GO:0004521; GO:0004525; GO:0005634; GO:0005654; GO:0005730; GO:0005829; GO:0006364; GO:0006396; GO:0010468; GO:0010586; GO:0010628; GO:0014069; GO:0017151; GO:0031053; GO:0031054; GO:0042803; GO:0045589; GO:0046332; GO:0046872; GO:0050727; GO:0050829; GO:0050830; GO:0070412; GO:0070877; GO:0070878; GO:0098978; GO:2000628 10683 XM_029333908.2 5742 6034 3156 4614 3456 Q4R4J0 9.03e-62 Rho GDP-dissociation inhibitor 1 (Rho GDI 1) (Rho-GDI alpha) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526] GO:0005094; GO:0005096; GO:0005737; GO:0007266; GO:0071526 10684 XR_003824835.2 724 464 143 465 293 NA NA NA NA NA NA 10685 XR_006394140.1 10 0 3 2 41 NA NA NA NA NA NA 10686 XR_006393369.1 0 0 21 2 1 NA NA NA NA NA NA 10687 XM_044320937.1 779 890 528 1240 220 Q6ZWJ1 9.15e-74 Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (STX4-interacting protein) (Synip) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; cellular response to type II interferon [GO:0071346]; insulin receptor signaling pathway [GO:0008286]; positive regulation of cell cycle G1/S phase transition [GO:1902808]; positive regulation of keratinocyte proliferation [GO:0010838]; protein stabilization [GO:0050821]; protein targeting [GO:0006605]; regulation of glucose transmembrane transport [GO:0010827]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072] GO:0006605; GO:0006974; GO:0008286; GO:0010827; GO:0010838; GO:0019905; GO:0031410; GO:0045335; GO:0050821; GO:0061178; GO:0070062; GO:0071346; GO:0098685; GO:0099072; GO:1902808 10688 XM_044321240.1 16 0 0 0 17 NA NA NA NA NA NA 10689 XM_029355522.2 985 501 491 506 620 Q5PPZ9 2.23e-78 Rap1 GTPase-GDP dissociation stimulator 1-B (Rap1gds1-B protein) (RalB-binding protein B) (XsmgGDS-B) (smgGDS-B) Xenopus laevis (African clawed frog) positive regulation of GTPase activity [GO:0043547]; small GTPase mediated signal transduction [GO:0007264] GO:0005085; GO:0005096; GO:0005739; GO:0005783; GO:0005829; GO:0007264; GO:0031267; GO:0043547 10690 XM_029348421.2 38 45 0 320 65 NA NA NA NA NA NA 10691 XR_003823496.2 0 0 8 4 0 NA NA NA NA NA NA 10692 XR_006391754.1 40 61 31 36 10 NA NA NA NA NA NA 10693 XM_029357021.2 181 51 11 338 47 NA NA NA NA NA NA 10694 XR_003826093.2 107 126 106 142 134 NA NA NA NA NA NA 10695 XM_044315511.1 13 13 74 0 194 NA NA NA NA NA NA 10696 XR_006396362.1 48 36 37 35 23 NA NA NA NA NA NA 10697 XR_006395003.1 55 32 6 55 6 NA NA NA NA NA NA 10698 XM_029351481.2 0 0 0 12 7 NA NA NA NA NA NA 10699 XM_029334598.2 4536 2725 2521 4526 2682 Q8IUK5 4.15e-48 Plexin domain-containing protein 1 (Tumor endothelial marker 3) (Tumor endothelial marker 7) Homo sapiens (Human) angiogenesis [GO:0001525]; spinal cord development [GO:0021510] GO:0001525; GO:0005576; GO:0005615; GO:0005737; GO:0005886; GO:0005923; GO:0021510; GO:0030425; GO:0043025; GO:0043235 10700 XM_029325147.2 10 0 3 0 1 NA NA NA NA NA NA 10701 XM_029328809.2 64 208 183 98 239 Q8HZ69 9.07e-132 Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.-) (Dimethylaniline oxidase 2) (FMO 1B1) (Pulmonary flavin-containing monooxygenase 2) (FMO 2) Gorilla gorilla gorilla (Western lowland gorilla) NADPH oxidation [GO:0070995] GO:0004497; GO:0004499; GO:0005789; GO:0016020; GO:0047822; GO:0050660; GO:0050661; GO:0070995 10702 XM_044307444.1 0 0 5 0 18 NA NA NA NA NA NA 10703 XR_006393390.1 236 178 409 534 213 NA NA NA NA NA NA 10704 XM_044326077.1 2 8 0 6 10 NA NA NA NA NA NA 10705 XM_044310136.1 0 0 11 0 0 NA NA NA NA NA NA 10706 XR_003827423.2 11 0 16 5 6 Q09575 1.93e-39 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 10707 XM_044314374.1 0 7 0 3 0 NA NA NA NA NA NA 10708 XM_029332014.2 118 64 78 100 263 Q4R7T7 4.99e-21 Tubulin delta chain (Delta-tubulin) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) cell projection organization [GO:0030030]; microtubule-based process [GO:0007017]; positive regulation of smoothened signaling pathway [GO:0045880] GO:0005200; GO:0005525; GO:0005634; GO:0005737; GO:0005814; GO:0005874; GO:0005929; GO:0007017; GO:0030030; GO:0045880 10709 XM_044309007.1 0 25 0 0 51 NA NA NA NA NA NA 10710 XM_044311838.1 2 25 6 0 8 Q96AY4 6.86e-85 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10711 XM_044311838.1 2 25 6 0 8 Q96AY4 2.76e-80 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10712 XM_044311838.1 2 25 6 0 8 Q96AY4 4.53e-80 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10713 XM_044311838.1 2 25 6 0 8 Q96AY4 1.16e-78 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10714 XM_044311838.1 2 25 6 0 8 Q96AY4 9.85e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10715 XM_044311838.1 2 25 6 0 8 Q96AY4 7.93e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10716 XM_029330297.2 890 587 511 817 944 Q6P4S6 9e-165 Serine/threonine-protein kinase SIK3 (EC 2.7.11.1) (Salt-inducible kinase 3) (SIK-3) (Serine/threonine-protein kinase QSK) Mus musculus (Mouse) cartilage development involved in endochondral bone morphogenesis [GO:0060351]; endochondral ossification [GO:0001958]; intracellular signal transduction [GO:0035556]; limb morphogenesis [GO:0035108]; microtubule cytoskeleton organization [GO:0000226]; multicellular organism growth [GO:0035264]; positive regulation of TORC1 signaling [GO:1904263]; positive regulation of TORC2 signaling [GO:1904515]; protein phosphorylation [GO:0006468]; regulation of protein localization [GO:0032880]; skeletal system morphogenesis [GO:0048705] GO:0000226; GO:0000287; GO:0001958; GO:0004674; GO:0005524; GO:0005654; GO:0005737; GO:0006468; GO:0032880; GO:0035108; GO:0035264; GO:0035556; GO:0048705; GO:0050321; GO:0060351; GO:0106310; GO:1904263; GO:1904515 10717 XM_044322435.1 0 3 0 0 11 NA NA NA NA NA NA 10718 XM_029346548.2 371 216 0 0 54 Q1LZA0 5.02e-142 GPI mannosyltransferase 3 (EC 2.4.1.-) (GPI mannosyltransferase III) (GPI-MT-III) (Phosphatidylinositol-glycan biosynthesis class B protein) (PIG-B) Bos taurus (Bovine) GPI anchor biosynthetic process [GO:0006506] GO:0000026; GO:0000030; GO:0005789; GO:0006506 10719 XM_029343353.2 362 198 143 220 205 Q6P881 5.14e-44 Non-structural maintenance of chromosomes element 1 homolog (Non-SMC element 1 homolog) (EC 2.3.2.27) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) DNA recombination [GO:0006310]; DNA repair [GO:0006281]; positive regulation of response to DNA damage stimulus [GO:2001022] GO:0000781; GO:0005634; GO:0006281; GO:0006310; GO:0030915; GO:0046872; GO:0046983; GO:0061630; GO:2001022 10720 XM_044320254.1 479 481 296 467 704 Q9GMB8 4.95e-54 Serine--tRNA ligase, cytoplasmic (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase) Bos taurus (Bovine) cytoplasmic translation [GO:0002181]; negative regulation of angiogenesis [GO:0016525]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular endothelial growth factor production [GO:1904046]; selenocysteine incorporation [GO:0001514]; selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]; seryl-tRNA aminoacylation [GO:0006434] GO:0000049; GO:0000122; GO:0000978; GO:0001514; GO:0002181; GO:0004828; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006434; GO:0016525; GO:0019899; GO:0042803; GO:0097056; GO:0098619; GO:1904046 10721 XM_029330409.2 818 1277 422 493 797 NA NA NA NA NA NA 10722 XM_029328940.2 4072 3894 2855 5001 3365 Q7TN02 8.91e-22 Mediator of RNA polymerase II transcription subunit 26 (Cofactor required for Sp1 transcriptional activation subunit 7) (CRSP complex subunit 7) (Mediator complex subunit 26) Mus musculus (Mouse) positive regulation of gene expression [GO:0010628]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA polymerase II preinitiation complex assembly [GO:0051123] GO:0003712; GO:0005634; GO:0005654; GO:0006357; GO:0010628; GO:0016592; GO:0032968; GO:0051123; GO:0060261; GO:0070847 10723 XM_029329383.2 253 159 139 285 221 Q5QQ57 0 Xylosyltransferase 1 (EC 2.4.2.26) (Peptide O-xylosyltransferase 1) (Xylosyltransferase I) Pan troglodytes (Chimpanzee) chondroitin sulfate biosynthetic process [GO:0030206]; chondroitin sulfate proteoglycan biosynthetic process [GO:0050650]; embryonic skeletal system development [GO:0048706]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; ossification involved in bone maturation [GO:0043931]; proteoglycan biosynthetic process [GO:0030166] GO:0000137; GO:0000139; GO:0005615; GO:0015012; GO:0030158; GO:0030166; GO:0030206; GO:0043931; GO:0046872; GO:0048706; GO:0050650 10724 XM_044325489.1 0 15 1 28 2 Q6DIV6 8.06e-47 Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Solute carrier family 32 member 1) (Vesicular GABA transporter) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) beta-alanine transport [GO:0001762]; gamma-aminobutyric acid import [GO:0051939]; gamma-aminobutyric acid transport [GO:0015812]; glycine transport [GO:0015816]; neurotransmitter transport [GO:0006836] GO:0001762; GO:0006836; GO:0008021; GO:0015185; GO:0015187; GO:0015812; GO:0015816; GO:0030659; GO:0042995; GO:0051939; GO:0098793; GO:0140799; GO:0140800 10725 XM_044326064.1 2061 2943 1226 1930 1148 Q6NZW8 3.5e-118 ADP-ribosylation factor-like protein 8B-A Danio rerio (Zebrafish) (Brachydanio rerio) anterograde axonal transport [GO:0008089]; autophagosome-lysosome fusion [GO:0061909]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; late endosome to lysosome transport [GO:1902774]; lysosome localization [GO:0032418]; protein transport [GO:0015031] GO:0003924; GO:0005525; GO:0005764; GO:0005765; GO:0005819; GO:0007059; GO:0008089; GO:0015031; GO:0031902; GO:0032418; GO:0051301; GO:0061909; GO:1902774; GO:1904115 10726 XM_029344710.2 130 95 155 25 72 NA NA NA NA NA NA 10727 XM_044328244.1 1735 1882 1367 2531 1968 NA NA NA NA NA NA 10728 XM_029346444.2 103 0 0 262 0 Q6ZQ11 0 Chondroitin sulfate synthase 1 (EC 2.4.1.175) (EC 2.4.1.226) (Chondroitin glucuronyltransferase 1) (Chondroitin synthase 1) (ChSy-1) (Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1) (N-acetylgalactosaminyltransferase 1) Mus musculus (Mouse) bone morphogenesis [GO:0060349]; cartilage development [GO:0051216]; chondrocyte development [GO:0002063]; chondroitin sulfate biosynthetic process [GO:0030206]; negative regulation of ossification [GO:0030279]; positive regulation of smoothened signaling pathway [GO:0045880]; proximal/distal pattern formation [GO:0009954]; response to nutrient levels [GO:0031667]; sulfation [GO:0051923] GO:0002063; GO:0005576; GO:0005794; GO:0008376; GO:0009954; GO:0016757; GO:0030206; GO:0030279; GO:0031667; GO:0032580; GO:0045880; GO:0046872; GO:0047238; GO:0050510; GO:0051216; GO:0051923; GO:0060349 10729 XM_029354795.2 0 28 77 79 0 NA NA NA NA NA NA 10730 XM_044312170.1 0 14 21 0 0 NA NA NA NA NA NA 10731 XR_003827018.2 601 687 527 789 419 NA NA NA NA NA NA 10732 XM_044316742.1 0 5 0 14 0 NA NA NA NA NA NA 10733 XM_044323569.1 24 0 48 18 0 NA NA NA NA NA NA 10734 XM_044324336.1 2525 1734 805 2542 1297 Q8BXG3 4.52e-157 Intraflagellar transport protein 57 homolog (HIP1-interacting protein) Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cilium assembly [GO:0060271]; heart looping [GO:0001947]; intraciliary anterograde transport [GO:0035720]; intraciliary transport [GO:0042073]; keratinocyte proliferation [GO:0043616]; left/right pattern formation [GO:0060972]; motile cilium assembly [GO:0044458]; negative regulation of keratinocyte proliferation [GO:0010839]; neural tube closure [GO:0001843]; non-motile cilium assembly [GO:1905515]; regulation of apoptotic process [GO:0042981]; smoothened signaling pathway [GO:0007224] GO:0001843; GO:0001947; GO:0003677; GO:0005794; GO:0005813; GO:0005929; GO:0005930; GO:0006915; GO:0006919; GO:0007224; GO:0010839; GO:0030992; GO:0032391; GO:0035720; GO:0036064; GO:0042073; GO:0042981; GO:0043616; GO:0044292; GO:0044458; GO:0060271; GO:0060972; GO:0097546; GO:1905515 10735 XR_006397708.1 42 133 157 265 132 Q7RTR2 5.38e-36 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 10736 XR_006397708.1 42 133 157 265 132 Q7RTR2 7.4e-27 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 10737 XR_006397708.1 42 133 157 265 132 Q7RTR2 1.28e-21 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 10738 XR_006397708.1 42 133 157 265 132 Q7RTR2 2.58e-21 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 10739 XM_029343927.2 386 98 74 4 278 Q13360 7.56e-43 Zinc finger protein 177 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000977; GO:0000981; GO:0001227; GO:0005634; GO:0006357; GO:0046872; GO:0072562; GO:1990837 10740 XM_029343927.2 386 98 74 4 278 Q13360 1.93e-24 Zinc finger protein 177 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000977; GO:0000981; GO:0001227; GO:0005634; GO:0006357; GO:0046872; GO:0072562; GO:1990837 10741 XM_044324322.1 28 0 0 35 33 NA NA NA NA NA NA 10742 XM_044322101.1 1047 748 677 849 1216 P55112 1.3e-42 Zinc metalloproteinase nas-4 (EC 3.4.24.-) (Nematode astacin 4) Caenorhabditis elegans proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0006508; GO:0008270 10743 XM_044327599.1 80 28 165 192 196 Q96AY4 3.69e-95 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10744 XM_044327599.1 80 28 165 192 196 Q96AY4 3.35e-93 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10745 XM_044327599.1 80 28 165 192 196 Q96AY4 8.38e-93 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10746 XM_044327599.1 80 28 165 192 196 Q96AY4 5.68e-91 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10747 XM_044327599.1 80 28 165 192 196 Q96AY4 9.06e-91 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10748 XM_044327599.1 80 28 165 192 196 Q96AY4 7.3e-88 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10749 XM_044327599.1 80 28 165 192 196 Q96AY4 4.74e-87 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10750 XM_044327599.1 80 28 165 192 196 Q96AY4 5.79e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10751 XR_006392363.1 12 0 3 0 3 NA NA NA NA NA NA 10752 XM_029354446.2 63 488 24 131 151 NA NA NA NA NA NA 10753 XM_029334799.2 165 0 8 0 123 G3M4F8 9.63e-46 Octopamine receptor beta-2R (CsOA2B2) Chilo suppressalis (Asiatic rice borer moth) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cellular response to amine stimulus [GO:0071418]; octopamine signaling pathway [GO:0071927]; tyramine signaling pathway [GO:0071928] GO:0004989; GO:0005886; GO:0007189; GO:0008226; GO:0016020; GO:0071418; GO:0071927; GO:0071928 10754 XM_044318643.1 0 0 26 0 0 Q7TNH6 1.72e-44 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 10755 XM_044318643.1 0 0 26 0 0 Q7TNH6 1.59e-43 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 10756 XM_044318643.1 0 0 26 0 0 Q7TNH6 4.15e-38 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 10757 XM_029355715.1 8 0 0 5 9 NA NA NA NA NA NA 10758 XM_029335131.2 20 0 0 0 0 NA NA NA NA NA NA 10759 XM_044311167.1 291 78 28 32 72 Q9CUX1 8.88e-84 52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (THAP domain-containing protein 0) (THAP domain-containing protein 12) Mus musculus (Mouse) NA GO:0003677; GO:0005634; GO:0046872; GO:0046983 10760 XR_006395623.1 13 9 9 1 6 NA NA NA NA NA NA 10761 XM_029339392.2 1086 649 541 946 685 Q62165 1.42e-28 Dystroglycan 1 (Dystroglycan) (Dystrophin-associated glycoprotein 1) [Cleaved into: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta-DG)] Mus musculus (Mouse) aging [GO:0007568]; angiogenesis involved in wound healing [GO:0060055]; axon guidance [GO:0007411]; axon regeneration [GO:0031103]; basement membrane organization [GO:0071711]; branching involved in salivary gland morphogenesis [GO:0060445]; calcium-dependent cell-matrix adhesion [GO:0016340]; cellular response to cholesterol [GO:0071397]; cellular response to mechanical stimulus [GO:0071260]; commissural neuron axon guidance [GO:0071679]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; membrane protein ectodomain proteolysis [GO:0006509]; microtubule anchoring [GO:0034453]; morphogenesis of an epithelial sheet [GO:0002011]; morphogenesis of an epithelium [GO:0002009]; muscle attachment [GO:0016203]; myelination in peripheral nervous system [GO:0022011]; negative regulation of cell migration [GO:0030336]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase B signaling [GO:0051898]; nerve development [GO:0021675]; nerve maturation [GO:0021682]; positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of myelination [GO:0031643]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein kinase activity [GO:0045860]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gastrulation [GO:0010470]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of synapse organization [GO:0050807]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; response to peptide hormone [GO:0043434]; retrograde trans-synaptic signaling by trans-synaptic protein complex [GO:0098942]; Schwann cell development [GO:0014044]; skeletal muscle tissue regeneration [GO:0043403] GO:0001618; GO:0001954; GO:0002009; GO:0002011; GO:0002162; GO:0003779; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005634; GO:0005654; GO:0005737; GO:0005856; GO:0005886; GO:0005911; GO:0005912; GO:0005925; GO:0006509; GO:0007411; GO:0007568; GO:0008307; GO:0009897; GO:0010470; GO:0010717; GO:0014044; GO:0014894; GO:0015631; GO:0016010; GO:0016011; GO:0016020; GO:0016203; GO:0016323; GO:0016340; GO:0017166; GO:0021675; GO:0021682; GO:0022011; GO:0030027; GO:0030175; GO:0030336; GO:0031103; GO:0031643; GO:0033268; GO:0034399; GO:0034453; GO:0042169; GO:0042383; GO:0043034; GO:0043231; GO:0043236; GO:0043237; GO:0043403; GO:0043409; GO:0043434; GO:0044853; GO:0045121; GO:0045202; GO:0045211; GO:0045860; GO:0048714; GO:0050807; GO:0051393; GO:0051898; GO:0060055; GO:0060441; GO:0060445; GO:0070938; GO:0071260; GO:0071397; GO:0071679; GO:0071711; GO:0098696; GO:0098942; GO:0098978; GO:0098982; GO:0099524; GO:1904261 10762 XM_029339392.2 1086 649 541 946 685 Q62165 9.96e-21 Dystroglycan 1 (Dystroglycan) (Dystrophin-associated glycoprotein 1) [Cleaved into: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta-DG)] Mus musculus (Mouse) aging [GO:0007568]; angiogenesis involved in wound healing [GO:0060055]; axon guidance [GO:0007411]; axon regeneration [GO:0031103]; basement membrane organization [GO:0071711]; branching involved in salivary gland morphogenesis [GO:0060445]; calcium-dependent cell-matrix adhesion [GO:0016340]; cellular response to cholesterol [GO:0071397]; cellular response to mechanical stimulus [GO:0071260]; commissural neuron axon guidance [GO:0071679]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; membrane protein ectodomain proteolysis [GO:0006509]; microtubule anchoring [GO:0034453]; morphogenesis of an epithelial sheet [GO:0002011]; morphogenesis of an epithelium [GO:0002009]; muscle attachment [GO:0016203]; myelination in peripheral nervous system [GO:0022011]; negative regulation of cell migration [GO:0030336]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase B signaling [GO:0051898]; nerve development [GO:0021675]; nerve maturation [GO:0021682]; positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of myelination [GO:0031643]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein kinase activity [GO:0045860]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gastrulation [GO:0010470]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of synapse organization [GO:0050807]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; response to peptide hormone [GO:0043434]; retrograde trans-synaptic signaling by trans-synaptic protein complex [GO:0098942]; Schwann cell development [GO:0014044]; skeletal muscle tissue regeneration [GO:0043403] GO:0001618; GO:0001954; GO:0002009; GO:0002011; GO:0002162; GO:0003779; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005634; GO:0005654; GO:0005737; GO:0005856; GO:0005886; GO:0005911; GO:0005912; GO:0005925; GO:0006509; GO:0007411; GO:0007568; GO:0008307; GO:0009897; GO:0010470; GO:0010717; GO:0014044; GO:0014894; GO:0015631; GO:0016010; GO:0016011; GO:0016020; GO:0016203; GO:0016323; GO:0016340; GO:0017166; GO:0021675; GO:0021682; GO:0022011; GO:0030027; GO:0030175; GO:0030336; GO:0031103; GO:0031643; GO:0033268; GO:0034399; GO:0034453; GO:0042169; GO:0042383; GO:0043034; GO:0043231; GO:0043236; GO:0043237; GO:0043403; GO:0043409; GO:0043434; GO:0044853; GO:0045121; GO:0045202; GO:0045211; GO:0045860; GO:0048714; GO:0050807; GO:0051393; GO:0051898; GO:0060055; GO:0060441; GO:0060445; GO:0070938; GO:0071260; GO:0071397; GO:0071679; GO:0071711; GO:0098696; GO:0098942; GO:0098978; GO:0098982; GO:0099524; GO:1904261 10763 XM_044319518.1 49 10 10 23 59 NA NA NA NA NA NA 10764 XM_029341011.2 115 57 39 117 18 A6H603 1.01e-97 NACHT domain- and WD repeat-containing protein 1 Mus musculus (Mouse) negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of gene expression [GO:0010628] GO:0005524; GO:0005730; GO:0005829; GO:0010628; GO:0032088 10765 XM_029332853.2 610 444 179 550 84 P97767 8.56e-154 Eyes absent homolog 1 (EC 3.1.3.16) (EC 3.1.3.48) Mus musculus (Mouse) anatomical structure development [GO:0048856]; animal organ morphogenesis [GO:0009887]; aorta morphogenesis [GO:0035909]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chromatin organization [GO:0006325]; cochlea morphogenesis [GO:0090103]; double-strand break repair [GO:0006302]; embryonic skeletal system morphogenesis [GO:0048704]; epithelial cell proliferation [GO:0050673]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; inner ear morphogenesis [GO:0042472]; mesodermal cell fate specification [GO:0007501]; metanephros development [GO:0001656]; middle ear morphogenesis [GO:0042474]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; neuron fate specification [GO:0048665]; otic vesicle development [GO:0071599]; otic vesicle morphogenesis [GO:0071600]; outer ear morphogenesis [GO:0042473]; outflow tract morphogenesis [GO:0003151]; pattern specification process [GO:0007389]; pharyngeal system development [GO:0060037]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of secondary heart field cardioblast proliferation [GO:0072513]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein dephosphorylation [GO:0006470]; protein sumoylation [GO:0016925]; regulation of neuron differentiation [GO:0045664]; response to ionizing radiation [GO:0010212]; semicircular canal morphogenesis [GO:0048752]; striated muscle tissue development [GO:0014706]; ureteric bud development [GO:0001657] GO:0001656; GO:0001657; GO:0001658; GO:0003151; GO:0003723; GO:0004725; GO:0005634; GO:0005654; GO:0005737; GO:0006302; GO:0006325; GO:0006470; GO:0007389; GO:0007501; GO:0009887; GO:0010212; GO:0014706; GO:0016604; GO:0016925; GO:0017018; GO:0030154; GO:0032991; GO:0032993; GO:0035909; GO:0042472; GO:0042473; GO:0042474; GO:0045165; GO:0045664; GO:0045739; GO:0045893; GO:0045944; GO:0046872; GO:0048665; GO:0048704; GO:0048752; GO:0048856; GO:0050673; GO:0050679; GO:0060037; GO:0071599; GO:0071600; GO:0072513; GO:0090103; GO:0097192; GO:0140793; GO:2001240 10766 XR_003828191.2 21 66 38 99 89 P42586 1.1e-40 Homeobox protein Nkx-2.2 (Homeobox protein NK-2 homolog B) Mus musculus (Mouse) astrocyte differentiation [GO:0048708]; cell development [GO:0048468]; cell differentiation [GO:0030154]; digestive tract development [GO:0048565]; endocrine pancreas development [GO:0031018]; negative regulation of neuron differentiation [GO:0045665]; nervous system development [GO:0007399]; neuroendocrine cell differentiation [GO:0061101]; neuron differentiation [GO:0030182]; neuron fate specification [GO:0048665]; oligodendrocyte development [GO:0014003]; oligodendrocyte differentiation [GO:0048709]; optic nerve development [GO:0021554]; pancreatic A cell fate commitment [GO:0003326]; pancreatic PP cell fate commitment [GO:0003329]; positive regulation of epithelial cell differentiation [GO:0030858]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; response to glucose [GO:0009749]; response to progesterone [GO:0032570]; smoothened signaling pathway [GO:0007224]; spinal cord motor neuron differentiation [GO:0021522]; spinal cord oligodendrocyte cell differentiation [GO:0021529]; spinal cord oligodendrocyte cell fate specification [GO:0021530]; type B pancreatic cell development [GO:0003323]; type B pancreatic cell differentiation [GO:0003309]; type B pancreatic cell fate commitment [GO:0003327]; ventral spinal cord interneuron fate determination [GO:0060580] GO:0000978; GO:0000981; GO:0000987; GO:0001228; GO:0003309; GO:0003323; GO:0003326; GO:0003327; GO:0003329; GO:0003700; GO:0005634; GO:0006355; GO:0006357; GO:0007224; GO:0007399; GO:0009749; GO:0010628; GO:0014003; GO:0021522; GO:0021529; GO:0021530; GO:0021554; GO:0030154; GO:0030182; GO:0030858; GO:0031018; GO:0032570; GO:0043565; GO:0045665; GO:0045666; GO:0045944; GO:0048468; GO:0048565; GO:0048665; GO:0048708; GO:0048709; GO:0048714; GO:0060580; GO:0061101 10767 XM_029339818.2 488 500 440 426 242 NA NA NA NA NA NA 10768 XM_029335009.2 0 0 8 0 9 NA NA NA NA NA NA 10769 XR_006397552.1 26 10 0 0 19 NA NA NA NA NA NA 10770 XM_029336912.2 259 243 298 0 37 Q765P7 7.83e-59 Protein MTSS 2 (Actin-bundling with BAIAP2 homology protein 1) (ABBA-1) (MTSS1-like protein) Homo sapiens (Human) activation of GTPase activity [GO:0090630]; cell projection assembly [GO:0030031]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; lamellipodium organization [GO:0097581]; membrane organization [GO:0061024]; plasma membrane organization [GO:0007009] GO:0003779; GO:0003785; GO:0005096; GO:0005543; GO:0005546; GO:0007009; GO:0009898; GO:0015629; GO:0030027; GO:0030031; GO:0030864; GO:0031267; GO:0032587; GO:0036120; GO:0061024; GO:0090630; GO:0097581 10771 XM_044311431.1 0 0 131 10 0 NA NA NA NA NA NA 10772 XM_029336774.2 4 68 29 66 3 G5EDE1 2.85e-59 Zinc finger protein GFI1 homolog pag-3 (Pattern of reporter gene expression abnormal protein 3) (Transcription factor pag-3) Caenorhabditis elegans negative regulation of apoptotic process [GO:0043066]; negative regulation of insulin secretion [GO:0046676]; negative regulation of neurotransmitter secretion [GO:0046929]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuroblast fate specification [GO:0014018]; regulation of backward locomotion [GO:0043058]; regulation of forward locomotion [GO:0043059]; regulation of neuron differentiation [GO:0045664]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000978; GO:0001222; GO:0001227; GO:0003700; GO:0003714; GO:0005634; GO:0006357; GO:0014018; GO:0030424; GO:0043058; GO:0043059; GO:0043066; GO:0043204; GO:0045664; GO:0046676; GO:0046872; GO:0046929 10773 XM_029351343.2 8593 9066 5588 6920 6884 P62278 4.79e-98 40S ribosomal protein S13 Rattus norvegicus (Rat) negative regulation of RNA splicing [GO:0033119]; translation at postsynapse [GO:0140242]; translation at presynapse [GO:0140236] GO:0003729; GO:0003735; GO:0005634; GO:0005730; GO:0005840; GO:0014069; GO:0022626; GO:0022627; GO:0033119; GO:0045202; GO:0048027; GO:0070181; GO:0098793; GO:0098794; GO:0140236; GO:0140242; GO:1990932 10774 XR_006394965.1 4 5 3 3 7 NA NA NA NA NA NA 10775 XM_029352170.2 2722 2305 1109 2094 1613 NA NA NA NA NA NA 10776 XM_044325548.1 99 0 0 16 0 Q9NSN8 3.12e-80 Gamma-1-syntrophin (G1SYN) (Syntrophin-4) (SYN4) Homo sapiens (Human) cell communication [GO:0007154] GO:0003779; GO:0005198; GO:0005634; GO:0005737; GO:0005856; GO:0007154; GO:0008022; GO:0016010; GO:0016013; GO:0032587 10777 XR_006395763.1 34 24 70 110 177 NA NA NA NA NA NA 10778 XM_044311889.1 1 11 0 8 3 NA NA NA NA NA NA 10779 XM_044324391.1 186 0 0 0 0 P35658 1.44e-78 Nuclear pore complex protein Nup214 (214 kDa nucleoporin) (Nucleoporin Nup214) (Protein CAN) Homo sapiens (Human) mitotic cell cycle [GO:0000278]; mRNA export from nucleus [GO:0006406]; nucleocytoplasmic transport [GO:0006913]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; regulation of cell cycle [GO:0051726]; regulation of nucleocytoplasmic transport [GO:0046822]; RNA export from nucleus [GO:0006405] GO:0000278; GO:0005049; GO:0005635; GO:0005643; GO:0005654; GO:0005829; GO:0006405; GO:0006406; GO:0006606; GO:0006611; GO:0006913; GO:0008139; GO:0017056; GO:0046822; GO:0051726; GO:1990876 10780 XM_044324391.1 186 0 0 0 0 P35658 3.19e-33 Nuclear pore complex protein Nup214 (214 kDa nucleoporin) (Nucleoporin Nup214) (Protein CAN) Homo sapiens (Human) mitotic cell cycle [GO:0000278]; mRNA export from nucleus [GO:0006406]; nucleocytoplasmic transport [GO:0006913]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; regulation of cell cycle [GO:0051726]; regulation of nucleocytoplasmic transport [GO:0046822]; RNA export from nucleus [GO:0006405] GO:0000278; GO:0005049; GO:0005635; GO:0005643; GO:0005654; GO:0005829; GO:0006405; GO:0006406; GO:0006606; GO:0006611; GO:0006913; GO:0008139; GO:0017056; GO:0046822; GO:0051726; GO:1990876 10781 XR_006393974.1 132 69 34 96 56 NA NA NA NA NA NA 10782 XM_044308550.1 12 9 10 49 18 NA NA NA NA NA NA 10783 XM_029334995.2 0 34 33 0 53 NA NA NA NA NA NA 10784 XM_029338780.2 70 17 50 74 111 P58308 1.27e-23 Orexin receptor type 2 (Ox-2-R) (Ox2-R) (Ox2R) (Hypocretin receptor type 2) Mus musculus (Mouse) circadian sleep/wake cycle process [GO:0022410]; feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; locomotion [GO:0040011]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; regulation of circadian sleep/wake cycle, wakefulness [GO:0010840]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0004930; GO:0005886; GO:0007186; GO:0007200; GO:0007218; GO:0007631; GO:0010840; GO:0016499; GO:0017046; GO:0022410; GO:0040011; GO:0051480 10785 XM_044321592.1 381 26 588 156 62 Q4U0G1 3.31e-143 CLIP-associating protein 1-A (Cytoplasmic linker-associated protein 1-A) (XCLASP1) Xenopus laevis (African clawed frog) cell cycle [GO:0007049]; cell division [GO:0051301]; microtubule anchoring [GO:0034453]; microtubule nucleation [GO:0007020]; microtubule organizing center organization [GO:0031023]; regulation of cellular component organization [GO:0051128] GO:0000776; GO:0005794; GO:0005815; GO:0005819; GO:0005874; GO:0007020; GO:0007049; GO:0031023; GO:0034453; GO:0051128; GO:0051301 10786 XM_044321592.1 381 26 588 156 62 Q4U0G1 2.68e-85 CLIP-associating protein 1-A (Cytoplasmic linker-associated protein 1-A) (XCLASP1) Xenopus laevis (African clawed frog) cell cycle [GO:0007049]; cell division [GO:0051301]; microtubule anchoring [GO:0034453]; microtubule nucleation [GO:0007020]; microtubule organizing center organization [GO:0031023]; regulation of cellular component organization [GO:0051128] GO:0000776; GO:0005794; GO:0005815; GO:0005819; GO:0005874; GO:0007020; GO:0007049; GO:0031023; GO:0034453; GO:0051128; GO:0051301 10787 XM_044321592.1 381 26 588 156 62 Q4U0G1 3.44e-49 CLIP-associating protein 1-A (Cytoplasmic linker-associated protein 1-A) (XCLASP1) Xenopus laevis (African clawed frog) cell cycle [GO:0007049]; cell division [GO:0051301]; microtubule anchoring [GO:0034453]; microtubule nucleation [GO:0007020]; microtubule organizing center organization [GO:0031023]; regulation of cellular component organization [GO:0051128] GO:0000776; GO:0005794; GO:0005815; GO:0005819; GO:0005874; GO:0007020; GO:0007049; GO:0031023; GO:0034453; GO:0051128; GO:0051301 10788 XR_006395627.1 0 0 6 6 0 NA NA NA NA NA NA 10789 XM_029333020.2 405 668 0 0 0 Q01970 4.94e-109 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-3) (Phospholipase C-beta-3) (PLC-beta-3) Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186]; lipid catabolic process [GO:0016042]; phosphatidylinositol metabolic process [GO:0046488]; phosphatidylinositol-mediated signaling [GO:0048015]; regulation of systemic arterial blood pressure [GO:0003073] GO:0003073; GO:0004435; GO:0004629; GO:0005509; GO:0005516; GO:0005634; GO:0005829; GO:0007186; GO:0016020; GO:0016042; GO:0032991; GO:0045296; GO:0046488; GO:0048015; GO:0060090; GO:0099524; GO:0140677 10790 XM_029349160.2 8478 8231 9123 8943 5652 NA NA NA NA NA NA 10791 XM_044327170.1 82 0 28 0 0 NA NA NA NA NA NA 10792 XM_029344211.2 1562 748 670 1408 1314 E9Q8T7 0 Dynein axonemal heavy chain 1 (Axonemal beta dynein heavy chain 1) (Ciliary dynein heavy chain 1) (mDHC7) Mus musculus (Mouse) cilium movement [GO:0003341]; cilium movement involved in cell motility [GO:0060294]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; flagellated sperm motility [GO:0030317]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018]; sperm axoneme assembly [GO:0007288] GO:0003341; GO:0003351; GO:0003777; GO:0005524; GO:0005576; GO:0005874; GO:0005930; GO:0007018; GO:0007288; GO:0008569; GO:0030286; GO:0030317; GO:0036126; GO:0036156; GO:0036159; GO:0045505; GO:0051959; GO:0060294 10793 XM_029331296.2 1582 873 575 871 528 Q8C206 1.05e-31 G-protein coupled receptor 157 Mus musculus (Mouse) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; circadian behavior [GO:0048512]; G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; radial glial cell differentiation [GO:0060019] GO:0004930; GO:0005886; GO:0007166; GO:0007186; GO:0007189; GO:0048512; GO:0051482; GO:0060019; GO:0060170 10794 XM_044321576.1 68 91 79 42 265 NA NA NA NA NA NA 10795 XM_044325144.1 392 137 519 140 1435 NA NA NA NA NA NA 10796 XM_029341761.2 5 14 0 0 50 NA NA NA NA NA NA 10797 XM_029329326.2 361 247 383 177 523 Q4R8N2 0 Protein lin-9 homolog Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) cell cycle [GO:0007049]; DNA biosynthetic process [GO:0071897]; DNA-templated transcription [GO:0006351] GO:0005654; GO:0006351; GO:0007049; GO:0017053; GO:0071897 10798 XM_029331965.2 0 306 0 120 0 B3EWZ3 1.97e-105 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 10799 XM_029331965.2 0 306 0 120 0 B3EWZ3 7.17e-99 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 10800 XM_029331965.2 0 306 0 120 0 B3EWZ3 1.09e-96 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 10801 XM_029331965.2 0 306 0 120 0 B3EWZ3 3.7e-91 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 10802 XM_029331965.2 0 306 0 120 0 B3EWZ3 1.79e-88 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 10803 XM_029331965.2 0 306 0 120 0 B3EWZ3 3.99e-83 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 10804 XM_029331965.2 0 306 0 120 0 B3EWZ3 6.35e-71 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 10805 XM_029331965.2 0 306 0 120 0 B3EWZ3 1.8e-24 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 10806 XM_044311218.1 0 0 3 0 7 NA NA NA NA NA NA 10807 XR_003826534.2 96 32 18 56 100 NA NA NA NA NA NA 10808 XM_044325592.1 143 81 44 183 162 NA NA NA NA NA NA 10809 XM_029330757.2 838 520 439 402 724 Q91WE2 1.06e-24 PSME3-interacting protein (NEFA-interacting nuclear protein NIP30) (PA28G-interacting protein) Mus musculus (Mouse) negative regulation of proteasomal protein catabolic process [GO:1901799]; negative regulation of protein binding [GO:0032091] GO:0005634; GO:0032091; GO:1901799 10810 XM_044306904.1 48 13 50 56 58 NA NA NA NA NA NA 10811 XM_044320033.1 304 173 203 240 346 NA NA NA NA NA NA 10812 XM_044308088.1 176 0 0 0 27 Q92113 3.47e-136 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Squalus acanthias (Spiny dogfish) steroid biosynthetic process [GO:0006694] GO:0004508; GO:0005506; GO:0006694; GO:0016020; GO:0020037; GO:0047442 10813 XM_044317168.1 24 15 30 2 69 NA NA NA NA NA NA 10814 XM_044323511.1 145 70 116 91 37 NA NA NA NA NA NA 10815 XM_044306993.1 611 565 374 523 594 NA NA NA NA NA NA 10816 XM_044308884.1 338 108 268 255 322 NA NA NA NA NA NA 10817 XM_029349804.2 2 4 0 0 13 NA NA NA NA NA NA 10818 XM_044321245.1 758 441 351 719 647 Q69ZW3 1.54e-63 EH domain-binding protein 1 Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; endocytosis [GO:0006897]; protein transport [GO:0015031] GO:0005654; GO:0005768; GO:0005815; GO:0005829; GO:0005886; GO:0006897; GO:0015031; GO:0030036; GO:0031941 10819 XM_044321245.1 758 441 351 719 647 Q69ZW3 1.31e-30 EH domain-binding protein 1 Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; endocytosis [GO:0006897]; protein transport [GO:0015031] GO:0005654; GO:0005768; GO:0005815; GO:0005829; GO:0005886; GO:0006897; GO:0015031; GO:0030036; GO:0031941 10820 XM_044321245.1 758 441 351 719 647 Q69ZW3 4.31e-24 EH domain-binding protein 1 Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; endocytosis [GO:0006897]; protein transport [GO:0015031] GO:0005654; GO:0005768; GO:0005815; GO:0005829; GO:0005886; GO:0006897; GO:0015031; GO:0030036; GO:0031941 10821 XM_044313337.1 178 62 68 97 256 NA NA NA NA NA NA 10822 XM_029352622.2 610 557 379 500 408 Q9YGL3 3.41e-54 Nuclear receptor subfamily 2 group E member 1 (Nuclear receptor TLX) (Protein tailless homolog) (Tll) Oryzias latipes (Japanese rice fish) (Japanese killifish) anatomical structure development [GO:0048856]; cell differentiation [GO:0030154]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000978; GO:0004879; GO:0005634; GO:0006357; GO:0008270; GO:0030154; GO:0048856 10823 XM_044328170.1 0 670 0 0 0 NA NA NA NA NA NA 10824 XR_006392746.1 94 20 66 14 88 NA NA NA NA NA NA 10825 XR_003823482.2 1 7 0 0 12 NA NA NA NA NA NA 10826 XM_044307352.1 11 9 26 15 55 P0DP43 6.04e-35 Cation channel sperm-associated auxiliary subunit epsilon (CatSper-epsilon) (CatSperepsilon) (C1orf101-like protein) Mus musculus (Mouse) flagellated sperm motility [GO:0030317]; sperm capacitation [GO:0048240] GO:0030317; GO:0036128; GO:0048240; GO:0097228 10827 XM_044328812.1 5 0 13 0 25 NA NA NA NA NA NA 10828 XM_029350900.2 127 76 61 56 85 NA NA NA NA NA NA 10829 XM_044329106.1 4 0 18 0 18 NA NA NA NA NA NA 10830 XM_044316341.1 2 6 0 1 0 P81274 7.69e-23 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 10831 XM_029323578.2 229 80 63 158 437 NA NA NA NA NA NA 10832 XM_029338218.2 460 281 331 169 316 NA NA NA NA NA NA 10833 XM_029356209.2 9 9 13 4 41 NA NA NA NA NA NA 10834 XM_044307302.1 434 167 238 486 353 Q9QWW1 2.11e-76 Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up-regulated during seizure and LTP 2) (Vesl-2) Mus musculus (Mouse) behavioral response to cocaine [GO:0048148]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; G protein-coupled glutamate receptor signaling pathway [GO:0007216]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of interleukin-2 production [GO:0032703]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; regulation of store-operated calcium entry [GO:2001256]; sensory perception of sound [GO:0007605] GO:0003779; GO:0005737; GO:0005829; GO:0005886; GO:0007216; GO:0007605; GO:0008277; GO:0014069; GO:0019904; GO:0030160; GO:0030425; GO:0032426; GO:0032703; GO:0035254; GO:0035256; GO:0035584; GO:0042802; GO:0043025; GO:0043229; GO:0044877; GO:0045177; GO:0048148; GO:0070885; GO:0098978; GO:2001256 10835 XM_029333604.2 331 407 203 429 387 NA NA NA NA NA NA 10836 XM_029344524.2 25 1041 110 123 240 P30975 2.21e-29 Tachykinin-like peptides receptor 99D (Tachykinin-like receptor at 99D) (dTKR) Drosophila melanogaster (Fruit fly) detection of chemical stimulus involved in sensory perception of smell [GO:0050911]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; neuropeptide signaling pathway [GO:0007218]; olfactory behavior [GO:0042048]; positive regulation of sensory perception of pain [GO:1904058]; tachykinin receptor signaling pathway [GO:0007217] GO:0004995; GO:0005886; GO:0007186; GO:0007217; GO:0007218; GO:0008188; GO:0016020; GO:0042048; GO:0050805; GO:0050911; GO:1904058 10837 XR_006393719.1 3 9 0 0 1 NA NA NA NA NA NA 10838 XM_029331568.2 2918 2841 1685 3566 3655 Q9UGV2 1.46e-72 Protein NDRG3 (N-myc downstream-regulated gene 3 protein) Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of cell growth [GO:0030308]; signal transduction [GO:0007165]; spermatogenesis [GO:0007283] GO:0005737; GO:0007165; GO:0007283; GO:0030154; GO:0030308; GO:0070062 10839 XM_044314967.1 140 65 47 3 19 NA NA NA NA NA NA 10840 XM_044319055.1 440 174 157 305 351 O76082 2.9e-59 Organic cation/carnitine transporter 2 (High-affinity sodium-dependent carnitine cotransporter) (Solute carrier family 22 member 5) Homo sapiens (Human) (R)-carnitine transmembrane transport [GO:1902270]; (R)-carnitine transport [GO:1900749]; carnitine transmembrane transport [GO:1902603]; carnitine transport [GO:0015879]; positive regulation of intestinal epithelial structure maintenance [GO:0060731]; quaternary ammonium group transport [GO:0015697]; response to symbiotic bacterium [GO:0009609]; response to tumor necrosis factor [GO:0034612]; response to type II interferon [GO:0034341]; sodium ion transport [GO:0006814]; sodium-dependent organic cation transport [GO:0070715]; transport across blood-brain barrier [GO:0150104]; xenobiotic detoxification by transmembrane export across the plasma membrane [GO:1990961] GO:0005524; GO:0005737; GO:0005783; GO:0005829; GO:0005886; GO:0006814; GO:0009609; GO:0009925; GO:0015226; GO:0015293; GO:0015651; GO:0015697; GO:0015879; GO:0016324; GO:0030165; GO:0031526; GO:0034341; GO:0034612; GO:0042910; GO:0060731; GO:0070062; GO:0070715; GO:0150104; GO:1900749; GO:1901235; GO:1902270; GO:1902603; GO:1990961 10841 XR_003827267.2 46 5 88 46 315 NA NA NA NA NA NA 10842 XM_029332317.2 124 104 197 73 52 Q9D1Q1 3.7e-23 M-phase phosphoprotein 6 Mus musculus (Mouse) maturation of 5.8S rRNA [GO:0000460] GO:0000176; GO:0000178; GO:0000460; GO:0003723; GO:0005634; GO:0005654; GO:0005730; GO:0005829 10843 XM_029328521.2 240 448 0 103 369 Q8WTS1 3.92e-115 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 (EC 2.3.1.51) (Abhydrolase domain-containing protein 5) (Lipid droplet-binding protein CGI-58) Homo sapiens (Human) cell differentiation [GO:0030154]; fatty acid metabolic process [GO:0006631]; lipid homeostasis [GO:0055088]; negative regulation of sequestering of triglyceride [GO:0010891]; phosphatidic acid biosynthetic process [GO:0006654]; positive regulation of lipoprotein lipase activity [GO:0051006]; positive regulation of triglyceride catabolic process [GO:0010898] GO:0003841; GO:0005654; GO:0005739; GO:0005811; GO:0005829; GO:0006631; GO:0006654; GO:0010891; GO:0010898; GO:0030154; GO:0042171; GO:0043231; GO:0051006; GO:0055088 10844 XM_029328397.2 1115 1654 1030 1264 1209 NA NA NA NA NA NA 10845 XR_006392803.1 0 13 0 0 0 NA NA NA NA NA NA 10846 XM_044315783.1 2 0 80 0 9 NA NA NA NA NA NA 10847 XM_029328198.2 162 51 81 93 128 NA NA NA NA NA NA 10848 XM_044312942.1 4 141 325 26 155 Q9WVM6 4.96e-37 Tolloid-like protein 2 (EC 3.4.24.-) Mus musculus (Mouse) cell differentiation [GO:0030154]; dorsal/ventral pattern formation [GO:0009953]; negative regulation of skeletal muscle tissue growth [GO:0048632]; protein processing [GO:0016485] GO:0004222; GO:0005509; GO:0005615; GO:0008270; GO:0009953; GO:0016485; GO:0030154; GO:0048632 10849 XM_044312942.1 4 141 325 26 155 Q9WVM6 2.44e-30 Tolloid-like protein 2 (EC 3.4.24.-) Mus musculus (Mouse) cell differentiation [GO:0030154]; dorsal/ventral pattern formation [GO:0009953]; negative regulation of skeletal muscle tissue growth [GO:0048632]; protein processing [GO:0016485] GO:0004222; GO:0005509; GO:0005615; GO:0008270; GO:0009953; GO:0016485; GO:0030154; GO:0048632 10850 XM_044319102.1 0 0 248 0 113 NA NA NA NA NA NA 10851 XM_029345594.2 787 41 0 386 278 Q9N1R6 1.47e-116 b(0,+)-type amino acid transporter 1 (b(0,+)AT) (4F2-LC6) (Glycoprotein-associated amino acid transporter b0,+AT1) (Solute carrier family 7 member 9) Oryctolagus cuniculus (Rabbit) L-cystine transport [GO:0015811]; neutral amino acid transport [GO:0015804] GO:0005886; GO:0015175; GO:0015184; GO:0015804; GO:0015811; GO:0016020; GO:0016324; GO:0031526; GO:0042605 10852 XM_044312961.1 51 55 163 285 167 O70244 5.33e-48 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 10853 XM_044312961.1 51 55 163 285 167 O70244 1.55e-41 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 10854 XM_044312961.1 51 55 163 285 167 O70244 3.37e-41 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 10855 XM_044312961.1 51 55 163 285 167 O70244 1.19e-40 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 10856 XM_044312961.1 51 55 163 285 167 O70244 1.23e-34 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 10857 XM_044312961.1 51 55 163 285 167 O70244 5.77e-34 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 10858 XM_044312961.1 51 55 163 285 167 O70244 2.01e-32 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 10859 XM_044312961.1 51 55 163 285 167 O70244 4.02e-31 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 10860 XM_044312961.1 51 55 163 285 167 O70244 4.25e-27 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 10861 XM_044312961.1 51 55 163 285 167 O70244 5.08e-27 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 10862 XM_044312961.1 51 55 163 285 167 O70244 3.33e-24 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 10863 XM_044312961.1 51 55 163 285 167 O70244 5.92e-24 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 10864 XM_044312961.1 51 55 163 285 167 O70244 2.05e-23 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 10865 XM_044315095.1 0 65 17 96 60 NA NA NA NA NA NA 10866 XM_029331601.2 0 214 159 98 18 Q14644 0 Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein) Homo sapiens (Human) negative regulation of Ras protein signal transduction [GO:0046580]; regulation of GTPase activity [GO:0043087]; signal transduction [GO:0007165] GO:0005096; GO:0005829; GO:0007165; GO:0009898; GO:0015278; GO:0043087; GO:0046580; GO:0046872 10867 XM_044323759.1 5 9 10 59 39 NA NA NA NA NA NA 10868 XM_044309184.1 263 189 267 77 405 NA NA NA NA NA NA 10869 XR_006394507.1 0 5 0 0 6 NA NA NA NA NA NA 10870 XM_029345906.2 20 12 0 0 6 NA NA NA NA NA NA 10871 XR_006396397.1 1491 1164 926 2204 1925 P50258 0 Tubulin alpha-1A chain (EC 3.6.5.-) Physarum polycephalum (Slime mold) microtubule-based process [GO:0007017] GO:0005200; GO:0005525; GO:0005634; GO:0005737; GO:0005819; GO:0005874; GO:0007017; GO:0016787; GO:0046872 10872 XR_006396397.1 1491 1164 926 2204 1925 P50258 0 Tubulin alpha-1A chain (EC 3.6.5.-) Physarum polycephalum (Slime mold) microtubule-based process [GO:0007017] GO:0005200; GO:0005525; GO:0005634; GO:0005737; GO:0005819; GO:0005874; GO:0007017; GO:0016787; GO:0046872 10873 XM_044314153.1 98 55 47 0 0 NA NA NA NA NA NA 10874 XR_003826429.2 15 0 14 10 125 NA NA NA NA NA NA 10875 XM_044322474.1 63 16 0 64 0 C6KFA3 2.14e-36 Adhesion G-protein coupled receptor G6 (G-protein coupled receptor 126) [Cleaved into: ADGRG6 N-terminal fragment (ADGRG6-NTF); ADGRG6 C-terminal fragment (ADGRG6-CTF)] Danio rerio (Zebrafish) (Brachydanio rerio) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cAMP-mediated signaling [GO:0019933]; cell surface receptor signaling pathway [GO:0007166]; ear development [GO:0043583]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; heart trabecula formation [GO:0060347]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; myelination of posterior lateral line nerve axons [GO:0048932]; ossification [GO:0001503]; peripheral nervous system myelin formation [GO:0032290]; regulation of sprouting angiogenesis [GO:1903670]; Schwann cell differentiation [GO:0014037]; semicircular canal fusion [GO:0060879] GO:0001503; GO:0004930; GO:0005518; GO:0005886; GO:0007005; GO:0007166; GO:0007186; GO:0007189; GO:0007507; GO:0014037; GO:0019933; GO:0022011; GO:0032290; GO:0042552; GO:0043236; GO:0043583; GO:0048932; GO:0050840; GO:0060347; GO:0060879; GO:1903670 10876 XM_029330586.2 0 0 0 0 17 Q8VIG3 1.52e-60 Radial spoke head 1 homolog (Male meiotic metaphase chromosome-associated acidic protein) (Meichroacidin) (Testis-specific gene A2 protein) Mus musculus (Mouse) axoneme assembly [GO:0035082]; meiotic cell cycle [GO:0051321]; spermatid development [GO:0007286] GO:0000794; GO:0001520; GO:0005634; GO:0005737; GO:0005829; GO:0005929; GO:0007286; GO:0031514; GO:0035082; GO:0036126; GO:0051321; GO:0072687 10877 XM_044326239.1 528 206 223 667 452 Q1LXK4 0 Putative helicase mov-10-B.1 (EC 3.6.4.13) Danio rerio (Zebrafish) (Brachydanio rerio) miRNA-mediated gene silencing by mRNA destabilization [GO:0035279]; RNA-mediated post-transcriptional gene silencing [GO:0035194] GO:0000932; GO:0003723; GO:0003724; GO:0005524; GO:0005829; GO:0016887; GO:0035194; GO:0035279; GO:0043186 10878 XM_029351211.2 76 73 85 94 155 P09019 7.45e-25 Homeobox protein Hox-B5 (Xhox-1B) (XlHbox-4) Xenopus laevis (African clawed frog) NA GO:0000981; GO:0003677; GO:0005634 10879 XM_044318467.1 114 0 45 132 0 NA NA NA NA NA NA 10880 XM_029324017.2 186 361 133 320 281 NA NA NA NA NA NA 10881 XM_044328656.1 452 238 88 166 179 Q92820 7.7e-86 Gamma-glutamyl hydrolase (EC 3.4.19.9) (Conjugase) (GH) (Gamma-Glu-X carboxypeptidase) Homo sapiens (Human) tetrahydrofolylpolyglutamate metabolic process [GO:0046900] GO:0005576; GO:0005615; GO:0005634; GO:0005773; GO:0008238; GO:0008242; GO:0034722; GO:0035578; GO:0035580; GO:0042470; GO:0046900; GO:0070062; GO:1904724 10882 XM_029340255.2 34 0 7 8 10 NA NA NA NA NA NA 10883 XM_029350150.2 5447 4133 2661 4957 3942 Q5DTZ6 4.91e-48 RING finger protein 150 Mus musculus (Mouse) ubiquitin-dependent protein catabolic process [GO:0006511] GO:0005737; GO:0006511; GO:0016020; GO:0046872; GO:0061630 10884 XM_029337541.2 1416 1702 870 1320 759 Q9UBX3 8.21e-111 Mitochondrial dicarboxylate carrier (DIC) (Solute carrier family 25 member 10) Homo sapiens (Human) dicarboxylic acid transport [GO:0006835]; gluconeogenesis [GO:0006094]; ion transport [GO:0006811]; lipid transport [GO:0006869]; malate transmembrane transport [GO:0071423]; mitochondrial transport [GO:0006839]; oxaloacetate transport [GO:0015729]; phosphate ion transmembrane transport [GO:0035435]; succinate transmembrane transport [GO:0071422]; sulfate transport [GO:0008272]; sulfide oxidation, using sulfide:quinone oxidoreductase [GO:0070221]; thiosulfate transport [GO:0015709] GO:0005310; GO:0005634; GO:0005654; GO:0005739; GO:0005743; GO:0006094; GO:0006811; GO:0006835; GO:0006839; GO:0006869; GO:0008272; GO:0015114; GO:0015116; GO:0015117; GO:0015131; GO:0015140; GO:0015141; GO:0015297; GO:0015709; GO:0015729; GO:0022857; GO:0035435; GO:0070221; GO:0071422; GO:0071423 10885 XM_044312461.1 0 44 0 96 241 NA NA NA NA NA NA 10886 XM_029324554.2 49 39 43 36 183 NA NA NA NA NA NA 10887 XM_029348884.2 57 0 21 30 23 NA NA NA NA NA NA 10888 XM_029355251.2 0 325 169 385 350 Q9EQC4 8.84e-71 Elongation of very long chain fatty acids protein 4 (EC 2.3.1.199) (3-keto acyl-CoA synthase Elovl4) (ELOVL fatty acid elongase 4) (ELOVL FA elongase 4) (Very long chain 3-ketoacyl-CoA synthase 4) (Very long chain 3-oxoacyl-CoA synthase 4) Mus musculus (Mouse) fatty acid elongation, monounsaturated fatty acid [GO:0034625]; fatty acid elongation, polyunsaturated fatty acid [GO:0034626]; fatty acid elongation, saturated fatty acid [GO:0019367]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; sphingolipid biosynthetic process [GO:0030148]; unsaturated fatty acid biosynthetic process [GO:0006636]; very long-chain fatty acid biosynthetic process [GO:0042761] GO:0005783; GO:0005789; GO:0006636; GO:0009922; GO:0019367; GO:0030148; GO:0034625; GO:0034626; GO:0035338; GO:0042761; GO:0102756 10889 XM_029330759.2 143 187 151 187 150 NA NA NA NA NA NA 10890 XM_044325946.1 709 34 182 357 71 Q66GV0 1.81e-51 Protein Mpv17 Xenopus laevis (African clawed frog) NA GO:0005743 10891 XM_029348770.2 189 130 92 241 227 NA NA NA NA NA NA 10892 XM_029345631.2 2149 1707 808 1416 1225 P62311 6.36e-34 U6 snRNA-associated Sm-like protein LSm3 Mus musculus (Mouse) mRNA splicing, via spliceosome [GO:0000398]; P-body assembly [GO:0033962] GO:0000398; GO:0000932; GO:0003723; GO:0005634; GO:0005688; GO:0030629; GO:0033962; GO:0046540; GO:0071005; GO:0071011; GO:0071013; GO:0120115; GO:1990726 10893 XM_044320681.1 1 5 35 4 16 NA NA NA NA NA NA 10894 XM_029343445.2 256 384 102 159 125 NA NA NA NA NA NA 10895 XM_044308474.1 25 0 11 28 37 NA NA NA NA NA NA 10896 XM_029348912.2 1356 374 0 676 664 O16025 0 Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (AOS) (EC 4.2.1.-) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)] Plexaura homomalla (Black sea rod) arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; lipid oxidation [GO:0034440]; oxylipin biosynthetic process [GO:0031408] GO:0005506; GO:0005737; GO:0006633; GO:0009978; GO:0016020; GO:0019369; GO:0020037; GO:0031408; GO:0034440; GO:0047677 10897 XM_029326872.2 5417 4201 2999 4417 3356 E9PSK7 0 C-Jun-amino-terminal kinase-interacting protein 3 (JIP-3) (JNK-interacting protein 3) (JNK MAP kinase scaffold protein 3) Rattus norvegicus (Rat) anterograde axonal protein transport [GO:0099641]; axon development [GO:0061564]; axon guidance [GO:0007411]; axon regeneration [GO:0031103]; forebrain development [GO:0030900]; in utero embryonic development [GO:0001701]; JNK cascade [GO:0007254]; lung alveolus development [GO:0048286]; lung morphogenesis [GO:0060425]; negative regulation of apoptotic process [GO:0043066]; neuron projection development [GO:0031175]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neuron migration [GO:2001224]; post-embryonic development [GO:0009791]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; regulation of gene expression [GO:0010468]; regulation of JNK cascade [GO:0046328]; respiratory gaseous exchange by respiratory system [GO:0007585]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0001701; GO:0005078; GO:0005737; GO:0005790; GO:0005886; GO:0007254; GO:0007411; GO:0007585; GO:0008104; GO:0008432; GO:0009791; GO:0010468; GO:0016192; GO:0019894; GO:0030159; GO:0030424; GO:0030425; GO:0030426; GO:0030673; GO:0030900; GO:0031103; GO:0031175; GO:0031410; GO:0031434; GO:0031435; GO:0043005; GO:0043066; GO:0043507; GO:0044297; GO:0045666; GO:0046328; GO:0046330; GO:0048286; GO:0048471; GO:0050821; GO:0060425; GO:0061564; GO:0099641; GO:1904115; GO:2001224 10898 XM_044322854.1 9 28 22 15 20 Q6DKK2 1.64e-22 Tetratricopeptide repeat protein 19, mitochondrial (TPR repeat protein 19) Homo sapiens (Human) mitochondrial respiratory chain complex III assembly [GO:0034551]; mitotic cytokinesis [GO:0000281] GO:0000281; GO:0005739; GO:0005743; GO:0005813; GO:0030496; GO:0034551; GO:0070469 10899 XM_044308667.1 1 134 90 0 214 NA NA NA NA NA NA 10900 XM_044321741.1 117 115 63 36 159 NA NA NA NA NA NA 10901 XM_044323108.1 138 121 64 58 44 NA NA NA NA NA NA 10902 XM_029338919.2 0 8 0 0 10 NA NA NA NA NA NA 10903 XM_044325844.1 52 28 0 12 20 NA NA NA NA NA NA 10904 XM_044320228.1 2896 2136 2758 2974 3074 NA NA NA NA NA NA 10905 XM_029324041.2 847 1405 959 920 992 O08807 1.41e-131 Peroxiredoxin-4 (EC 1.11.1.24) (Antioxidant enzyme AOE372) (Peroxiredoxin IV) (Prx-IV) (Thioredoxin peroxidase AO372) (Thioredoxin-dependent peroxide reductase A0372) (Thioredoxin-dependent peroxiredoxin 4) Mus musculus (Mouse) cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; protein maturation by protein folding [GO:0022417]; reactive oxygen species metabolic process [GO:0072593]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283] GO:0005615; GO:0005737; GO:0005739; GO:0005783; GO:0005790; GO:0005829; GO:0006979; GO:0007283; GO:0008584; GO:0018401; GO:0022417; GO:0030198; GO:0042802; GO:0045454; GO:0060090; GO:0072593; GO:0140313; GO:0140824; GO:2000255 10906 XM_029347085.2 664 985 587 758 819 NA NA NA NA NA NA 10907 XR_003828643.2 210 154 164 303 292 NA NA NA NA NA NA 10908 XM_044314232.1 0 0 11 0 8 NA NA NA NA NA NA 10909 XM_044325487.1 0 0 0 85 0 Q6DIV6 3.52e-47 Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Solute carrier family 32 member 1) (Vesicular GABA transporter) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) beta-alanine transport [GO:0001762]; gamma-aminobutyric acid import [GO:0051939]; gamma-aminobutyric acid transport [GO:0015812]; glycine transport [GO:0015816]; neurotransmitter transport [GO:0006836] GO:0001762; GO:0006836; GO:0008021; GO:0015185; GO:0015187; GO:0015812; GO:0015816; GO:0030659; GO:0042995; GO:0051939; GO:0098793; GO:0140799; GO:0140800 10910 XR_006393583.1 605 672 387 6 53 NA NA NA NA NA NA 10911 XM_044309091.1 1757 1318 826 1116 1759 P70168 0 Importin subunit beta-1 (Karyopherin subunit beta-1) (Nuclear factor p97) (Pore targeting complex 97 kDa subunit) (PTAC97) (SCG) Mus musculus (Mouse) astral microtubule organization [GO:0030953]; establishment of mitotic spindle localization [GO:0040001]; establishment of protein localization [GO:0045184]; mitotic chromosome movement towards spindle pole [GO:0007079]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly [GO:0090307]; protein import into nucleus [GO:0006606]; Ran protein signal transduction [GO:0031291]; ribosomal protein import into nucleus [GO:0006610]; RNA import into nucleus [GO:0006404] GO:0005634; GO:0005635; GO:0005643; GO:0005654; GO:0005737; GO:0005829; GO:0006404; GO:0006606; GO:0006610; GO:0007079; GO:0007080; GO:0008139; GO:0010494; GO:0019894; GO:0019899; GO:0019904; GO:0030953; GO:0031267; GO:0031291; GO:0031965; GO:0032991; GO:0040001; GO:0042564; GO:0044877; GO:0045184; GO:0051879; GO:0061608; GO:0061676; GO:0071782; GO:0090307 10912 XM_029338668.2 9187 10373 8535 19094 11913 Q5F413 2.9e-51 Stromal membrane-associated protein 2 (Stromal membrane-associated protein 1-like) Gallus gallus (Chicken) NA GO:0005096; GO:0005737; GO:0046872 10913 XM_044317902.1 32 33 46 46 78 NA NA NA NA NA NA 10914 XM_044318885.1 7287 5924 3962 7363 6409 NA NA NA NA NA NA 10915 XM_044319806.1 0 26 0 24 0 P97292 4.3e-21 Histamine H2 receptor (H2R) (HH2R) (Gastric receptor I) Mus musculus (Mouse) chemical synaptic transmission [GO:0007268]; digestive tract development [GO:0048565]; epithelial cell morphogenesis [GO:0003382]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; gastric acid secretion [GO:0001696]; gastrin-induced gastric acid secretion [GO:0001698]; gland development [GO:0048732]; histamine-induced gastric acid secretion [GO:0001697]; memory [GO:0007613]; negative regulation of arachidonic acid secretion [GO:1900139]; positive regulation of vasoconstriction [GO:0045907]; regulation of synaptic plasticity [GO:0048167]; toxin transport [GO:1901998]; visual learning [GO:0008542] GO:0001696; GO:0001697; GO:0001698; GO:0003382; GO:0004969; GO:0004993; GO:0005886; GO:0007187; GO:0007268; GO:0007613; GO:0008542; GO:0016020; GO:0030425; GO:0030594; GO:0045202; GO:0045907; GO:0048167; GO:0048565; GO:0048732; GO:1900139; GO:1901363; GO:1901998 10916 XM_029346117.2 738 374 312 475 495 NA NA NA NA NA NA 10917 XM_044321379.1 98 173 122 119 228 NA NA NA NA NA NA 10918 XM_029335919.2 196 226 182 281 152 NA NA NA NA NA NA 10919 XM_029330722.2 659 619 508 673 889 B5X4H8 9.06e-96 Riboflavin transporter 2 (RFT2) Salmo salar (Atlantic salmon) NA GO:0005886; GO:0032217 10920 XM_029334348.2 32 60 34 101 134 NA NA NA NA NA NA 10921 XM_044318581.1 573 414 370 448 317 Q68F72 2.18e-84 Solute carrier family 15 member 4 Xenopus laevis (African clawed frog) dipeptide import across plasma membrane [GO:0140206]; innate immune response [GO:0045087]; mast cell homeostasis [GO:0033023]; peptidoglycan transport [GO:0015835]; positive regulation of innate immune response [GO:0045089]; positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [GO:0070430]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of toll-like receptor 7 signaling pathway [GO:0034157]; positive regulation of toll-like receptor 8 signaling pathway [GO:0034161]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; protein transport [GO:0015031]; regulation of isotype switching to IgG isotypes [GO:0048302]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424] GO:0005290; GO:0005765; GO:0015031; GO:0015333; GO:0015647; GO:0015835; GO:0031901; GO:0033023; GO:0034157; GO:0034161; GO:0034165; GO:0036020; GO:0045087; GO:0045089; GO:0048302; GO:0070424; GO:0070430; GO:0070434; GO:0071916; GO:0140206 10922 XM_044328117.1 15 5 12 1 0 NA NA NA NA NA NA 10923 XR_006396814.1 172 103 11 115 148 NA NA NA NA NA NA 10924 XM_029350672.2 423 3313 691 1990 882 Q08289 9.27e-125 Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2) (Lambert-Eaton myasthenic syndrome antigen B) (MYSB) Homo sapiens (Human) calcium ion import [GO:0070509]; chemical synaptic transmission [GO:0007268]; membrane depolarization during atrial cardiac muscle cell action potential [GO:0098912]; membrane depolarization during AV node cell action potential [GO:0086045]; neuromuscular junction development [GO:0007528]; positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel [GO:1904879]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of high voltage-gated calcium channel activity [GO:1901843]; protein localization to plasma membrane [GO:0072659]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of voltage-gated calcium channel activity [GO:1901385]; visual perception [GO:0007601] GO:0005245; GO:0005262; GO:0005886; GO:0005891; GO:0007268; GO:0007528; GO:0007601; GO:0051015; GO:0051928; GO:0070509; GO:0072659; GO:0086045; GO:0086091; GO:0098684; GO:0098793; GO:0098912; GO:0099626; GO:1901385; GO:1901843; GO:1904879; GO:1990454 10925 XM_044309196.1 281 422 62 326 101 Q14457 7.65e-138 Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197) [Cleaved into: Beclin-1-C 35 kDa; Beclin-1-C 37 kDa] Homo sapiens (Human) aging [GO:0007568]; amyloid-beta metabolic process [GO:0050435]; apoptotic process [GO:0006915]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cell division [GO:0051301]; cellular defense response [GO:0006968]; cellular response to aluminum ion [GO:0071275]; cellular response to amino acid starvation [GO:0034198]; cellular response to copper ion [GO:0071280]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucose starvation [GO:0042149]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to nitrogen starvation [GO:0006995]; defense response to virus [GO:0051607]; early endosome to late endosome transport [GO:0045022]; engulfment of apoptotic cell [GO:0043652]; late endosome to vacuole transport [GO:0045324]; lysosome organization [GO:0007040]; macroautophagy [GO:0016236]; mitophagy [GO:0000423]; mitotic metaphase plate congression [GO:0007080]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagosome assembly [GO:1902902]; negative regulation of cell death [GO:0060548]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of lysosome organization [GO:1905672]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; neuron development [GO:0048666]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of attachment of mitotic spindle microtubules to kinetochore [GO:1902425]; positive regulation of autophagosome assembly [GO:2000786]; positive regulation of autophagy [GO:0010508]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of catalytic activity [GO:0050790]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241]; response to hypoxia [GO:0001666]; response to iron(II) ion [GO:0010040]; response to lead ion [GO:0010288]; response to mitochondrial depolarisation [GO:0098780]; response to vitamin E [GO:0033197]; response to xenobiotic stimulus [GO:0009410]; selective autophagy [GO:0061912]; suppression by virus of host autophagy [GO:0039521] GO:0000045; GO:0000407; GO:0000422; GO:0000423; GO:0001666; GO:0005737; GO:0005768; GO:0005776; GO:0005783; GO:0005789; GO:0005802; GO:0005829; GO:0006468; GO:0006622; GO:0006914; GO:0006915; GO:0006968; GO:0006995; GO:0007040; GO:0007080; GO:0007568; GO:0008285; GO:0009410; GO:0010008; GO:0010040; GO:0010288; GO:0010506; GO:0010508; GO:0010613; GO:0014068; GO:0016236; GO:0016241; GO:0016604; GO:0019898; GO:0019901; GO:0030425; GO:0031625; GO:0031966; GO:0032465; GO:0032801; GO:0033197; GO:0034198; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0039521; GO:0042149; GO:0042802; GO:0043066; GO:0043548; GO:0043652; GO:0045022; GO:0045324; GO:0045335; GO:0048666; GO:0050435; GO:0050790; GO:0051020; GO:0051301; GO:0051607; GO:0060548; GO:0061912; GO:0070301; GO:0071275; GO:0071280; GO:0071364; GO:0097352; GO:0098780; GO:1902425; GO:1902902; GO:1905672; GO:2000378; GO:2000786; GO:2001244 10926 XM_029331125.2 9 1 17 28 34 Q9C0A0 1.66e-27 Contactin-associated protein-like 4 (Cell recognition molecule Caspr4) Homo sapiens (Human) cell adhesion [GO:0007155]; regulation of grooming behavior [GO:2000821]; regulation of synaptic transmission, dopaminergic [GO:0032225]; regulation of synaptic transmission, GABAergic [GO:0032228] GO:0007155; GO:0032225; GO:0032228; GO:0042734; GO:0042995; GO:2000821 10927 XR_006394350.1 30 56 0 10 9 A3KN83 0 Protein strawberry notch homolog 1 (Monocyte protein 3) (MOP-3) Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355]; regulation of response to stimulus [GO:0048583] GO:0005634; GO:0006355; GO:0031490; GO:0042393; GO:0048583 10928 XM_044308455.1 3994 1178 3233 892 2153 NA NA NA NA NA NA 10929 XM_029343288.2 13611 12411 13015 14878 16743 Q9EQS0 5.96e-152 Transaldolase (EC 2.2.1.2) Rattus norvegicus (Rat) carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glyceraldehyde-3-phosphate metabolic process [GO:0019682]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052] GO:0004801; GO:0005634; GO:0005737; GO:0005829; GO:0005975; GO:0006002; GO:0006098; GO:0009052; GO:0019682; GO:0030246; GO:0042802; GO:0043231; GO:0048029 10930 XM_029349497.2 3 14 8 9 5 NA NA NA NA NA NA 10931 XM_029353075.2 657 526 415 687 846 Q2HJF4 3.54e-96 Phenazine biosynthesis-like domain-containing protein (EC 5.1.-.-) Bos taurus (Bovine) biosynthetic process [GO:0009058]; maintenance of gastrointestinal epithelium [GO:0030277]; negative regulation of SMAD protein signal transduction [GO:0060392]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512] GO:0005737; GO:0009058; GO:0016853; GO:0030277; GO:0030512; GO:0042802; GO:0060392 10932 XM_029337966.2 909 479 632 995 1159 A2CI35 0 Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein kinase) (Dusty PK) (Receptor-interacting serine/threonine-protein kinase 5) Strongylocentrotus purpuratus (Purple sea urchin) cellular response to fibroblast growth factor stimulus [GO:0044344]; embryonic organ development [GO:0048568]; negative regulation of apoptotic process [GO:0043066]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast growth factor receptor signaling pathway [GO:0045743] GO:0004674; GO:0004712; GO:0004713; GO:0005524; GO:0005737; GO:0016323; GO:0016324; GO:0043066; GO:0044344; GO:0045743; GO:0048568; GO:0070161; GO:0070374; GO:0106310 10933 XR_006395919.1 9 107 18 52 30 NA NA NA NA NA NA 10934 XM_044325160.1 0 109 0 23 72 Q866A2 1.51e-81 Neuronal acetylcholine receptor subunit alpha-7 Macaca mulatta (Rhesus macaque) associative learning [GO:0008306]; B cell activation [GO:0042113]; behavioral response to ethanol [GO:0048149]; behavioral response to nicotine [GO:0035095]; calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; cognition [GO:0050890]; dendrite arborization [GO:0140059]; dendritic spine organization [GO:0097061]; endocytosis [GO:0006897]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; generation of ovulation cycle rhythm [GO:0060112]; ion transmembrane transport [GO:0034220]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of tumor necrosis factor production [GO:0032720]; nervous system process [GO:0050877]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of CoA-transferase activity [GO:1905920]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure [GO:0001988]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; regulation of amyloid fibril formation [GO:1905906]; regulation of membrane potential [GO:0042391]; regulation of neuron death [GO:1901214]; regulation of norepinephrine secretion [GO:0014061]; regulation of synaptic transmission, dopaminergic [GO:0032225]; response to amyloid-beta [GO:1904645]; response to cold [GO:0009409]; response to food [GO:0032094]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; sensory processing [GO:0050893]; short-term memory [GO:0007614]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271]; T cell activation [GO:0042110] GO:0001540; GO:0001666; GO:0001933; GO:0001988; GO:0005231; GO:0005886; GO:0005892; GO:0006816; GO:0006874; GO:0006897; GO:0007165; GO:0007268; GO:0007271; GO:0007614; GO:0008284; GO:0008306; GO:0009409; GO:0009897; GO:0014061; GO:0015464; GO:0015643; GO:0016324; GO:0017081; GO:0022848; GO:0030317; GO:0030594; GO:0030673; GO:0032094; GO:0032225; GO:0032691; GO:0032715; GO:0032720; GO:0033138; GO:0034220; GO:0035094; GO:0035095; GO:0042110; GO:0042113; GO:0042166; GO:0042391; GO:0042734; GO:0042803; GO:0043005; GO:0043410; GO:0045202; GO:0045766; GO:0048149; GO:0050728; GO:0050877; GO:0050890; GO:0050893; GO:0051649; GO:0060112; GO:0070374; GO:0097061; GO:0098839; GO:0098978; GO:0098981; GO:0140059; GO:1900273; GO:1901214; GO:1902004; GO:1904315; GO:1904645; GO:1905906; GO:1905920; GO:2000463 10935 XM_029331609.2 1649 518 579 1037 916 Q14644 0 Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein) Homo sapiens (Human) negative regulation of Ras protein signal transduction [GO:0046580]; regulation of GTPase activity [GO:0043087]; signal transduction [GO:0007165] GO:0005096; GO:0005829; GO:0007165; GO:0009898; GO:0015278; GO:0043087; GO:0046580; GO:0046872 10936 XM_044325215.1 2 30 0 0 8 NA NA NA NA NA NA 10937 XM_029324247.2 0 0 0 0 8 Q96MB7 8.63e-37 Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease) Homo sapiens (Human) NA GO:0004518; GO:0005634; GO:0005829; GO:0005886; GO:0034451; GO:0046872 10938 XM_029328535.2 26 27 23 0 74 P35061 4.64e-56 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 10939 XR_006394388.1 102 44 7 38 44 NA NA NA NA NA NA 10940 XM_029335184.2 2 14 2 42 52 NA NA NA NA NA NA 10941 XM_029332684.2 60 1 32 37 127 NA NA NA NA NA NA 10942 XM_029348088.2 12 0 116 0 289 Q3UQ28 2.13e-136 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 10943 XM_029329319.2 0 42 0 0 71 NA NA NA NA NA NA 10944 XM_044311024.1 10 0 8 98 45 NA NA NA NA NA NA 10945 XM_029333586.2 128 544 83 4 1282 Q76KP1 3.33e-75 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Homo sapiens (Human) NA GO:0008376; GO:0032580; GO:0033842 10946 XM_029333586.2 128 544 83 4 1282 Q76KP1 9.37e-37 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Homo sapiens (Human) NA GO:0008376; GO:0032580; GO:0033842 10947 XM_029340068.2 94 101 108 38 134 Q8WYR4 1.41e-52 Radial spoke head 1 homolog (Cancer/testis antigen 79) (CT79) (Male meiotic metaphase chromosome-associated acidic protein) (Meichroacidin) (Testis-specific gene A2 protein) Homo sapiens (Human) axoneme assembly [GO:0035082]; meiotic cell cycle [GO:0051321]; spermatid development [GO:0007286] GO:0000794; GO:0001520; GO:0005634; GO:0005829; GO:0007286; GO:0031514; GO:0035082; GO:0051321; GO:0072687 10948 XM_044320599.1 397 163 152 250 368 Q969S8 4.44e-92 Polyamine deacetylase HDAC10 (EC 3.5.1.48) (EC 3.5.1.62) (Histone deacetylase 10) (HD10) Homo sapiens (Human) chromatin organization [GO:0006325]; DNA repair [GO:0006281]; histone deacetylation [GO:0016575]; homologous recombination [GO:0035825]; macroautophagy [GO:0016236]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-lysine deacetylation [GO:0034983]; polyamine deacetylation [GO:0106047]; positive regulation of mismatch repair [GO:0032425]; protein deacetylation [GO:0006476]; regulation of DNA-templated transcription [GO:0006355]; spermidine deacetylation [GO:0106048] GO:0000118; GO:0000122; GO:0004407; GO:0005634; GO:0005654; GO:0005737; GO:0006281; GO:0006325; GO:0006355; GO:0006476; GO:0008270; GO:0016236; GO:0016575; GO:0019213; GO:0019899; GO:0032425; GO:0033558; GO:0034983; GO:0035825; GO:0042826; GO:0045892; GO:0047609; GO:0047611; GO:0106047; GO:0106048 10949 XM_029348339.2 5473 7173 3737 9712 8002 P30051 0 Transcriptional enhancer factor TEF-1 (NTEF-1) (Protein GT-IIC) (TEA domain family member 1) (TEAD-1) (Transcription factor 13) (TCF-13) Mus musculus (Mouse) cellular response to retinoic acid [GO:0071300]; embryonic heart tube morphogenesis [GO:0003143]; embryonic organ development [GO:0048568]; heart development [GO:0007507]; hippo signaling [GO:0035329]; lateral mesoderm development [GO:0048368]; notochord development [GO:0030903]; paraxial mesoderm development [GO:0048339]; positive regulation of cell growth [GO:0030307]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein-containing complex assembly [GO:0065003]; regulation of cell population proliferation [GO:0042127]; regulation of DNA-templated transcription [GO:0006355]; regulation of gene expression [GO:0010468]; regulation of transcription by RNA polymerase II [GO:0006357]; transition between fast and slow fiber [GO:0014883] GO:0000978; GO:0000981; GO:0003143; GO:0003700; GO:0005634; GO:0005654; GO:0005667; GO:0006355; GO:0006357; GO:0007507; GO:0010468; GO:0014883; GO:0030307; GO:0030903; GO:0035329; GO:0042127; GO:0045893; GO:0045944; GO:0048339; GO:0048368; GO:0048568; GO:0065003; GO:0071300; GO:0071902; GO:0140552; GO:1902459; GO:1902895; GO:1990837 10950 XM_044316800.1 10 0 21 29 5 NA NA NA NA NA NA 10951 XM_044327356.1 110 73 29 68 90 NA NA NA NA NA NA 10952 XR_006395894.1 397 2208 3724 7099 2286 NA NA NA NA NA NA 10953 XM_029356763.2 0 171 0 860 2096 NA NA NA NA NA NA 10954 XR_006393120.1 68 2676 362 1127 727 NA NA NA NA NA NA 10955 XM_044328402.1 851 400 328 631 694 Q8BVV7 2.9e-58 Centrosomal protein of 95 kDa (Cep95) (Coiled-coil domain-containing protein 45) Mus musculus (Mouse) NA GO:0000922; GO:0005737; GO:0005813 10956 XM_029341808.2 1293 1362 970 1085 790 Q5TFE4 5.71e-91 5'-nucleotidase domain-containing protein 1 (EC 3.1.3.-) Homo sapiens (Human) NA GO:0008253; GO:0046872 10957 XR_006397409.1 0 0 0 55 173 NA NA NA NA NA NA 10958 XM_029342164.2 68 44 44 149 198 Q96L93 1.61e-104 Kinesin-like protein KIF16B (Sorting nexin-23) Homo sapiens (Human) early endosome to late endosome transport [GO:0045022]; endoderm development [GO:0007492]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; formation of primary germ layer [GO:0001704]; Golgi to endosome transport [GO:0006895]; microtubule-based movement [GO:0007018]; receptor catabolic process [GO:0032801]; regulation of receptor recycling [GO:0001919] GO:0001704; GO:0001919; GO:0003777; GO:0005524; GO:0005547; GO:0005737; GO:0005768; GO:0005769; GO:0005819; GO:0005829; GO:0005871; GO:0005874; GO:0006895; GO:0007018; GO:0007173; GO:0007492; GO:0008017; GO:0008543; GO:0008574; GO:0016887; GO:0031901; GO:0032266; GO:0032801; GO:0043325; GO:0045022; GO:0080025 10959 XM_044308248.1 271 232 83 98 36 Q8CGZ0 1.88e-31 Calcium homeostasis endoplasmic reticulum protein (SR-related CTD-associated factor 6) Mus musculus (Mouse) cellular calcium ion homeostasis [GO:0006874]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; release of sequestered calcium ion into cytosol [GO:0051209]; RNA processing [GO:0006396] GO:0003723; GO:0005737; GO:0006396; GO:0006874; GO:0008285; GO:0033017; GO:0044325; GO:0048471; GO:0051209; GO:0070886 10960 XR_003827134.2 42 41 25 36 43 NA NA NA NA NA NA 10961 XR_003825004.2 30 22 13 46 31 NA NA NA NA NA NA 10962 XM_044322883.1 265 147 100 513 723 P02467 1.37e-62 Collagen alpha-2(I) chain (Alpha-2 type I collagen) Gallus gallus (Chicken) extracellular matrix organization [GO:0030198] GO:0005201; GO:0005583; GO:0005584; GO:0005615; GO:0030198; GO:0031012; GO:0046872 10963 XM_029343910.2 159 181 0 272 0 Q2PZL6 0 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 10964 XM_029343910.2 159 181 0 272 0 Q2PZL6 0 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 10965 XM_029343910.2 159 181 0 272 0 Q2PZL6 0 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 10966 XM_029343910.2 159 181 0 272 0 Q2PZL6 0 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 10967 XM_029343910.2 159 181 0 272 0 Q2PZL6 0 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 10968 XM_029343910.2 159 181 0 272 0 Q2PZL6 0 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 10969 XM_029343910.2 159 181 0 272 0 Q2PZL6 0 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 10970 XM_029343910.2 159 181 0 272 0 Q2PZL6 0 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 10971 XM_029343910.2 159 181 0 272 0 Q2PZL6 0 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 10972 XM_029337644.2 74 31 36 49 153 NA NA NA NA NA NA 10973 XR_006392224.1 0 23 22 0 71 NA NA NA NA NA NA 10974 XM_029349107.2 224 1 0 158 2 F6R2G2 5.57e-22 NLR family CARD domain-containing protein 4 (Ice protease-activating factor) (Ipaf) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) apoptotic process [GO:0006915]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; regulation of apoptotic process [GO:0042981] GO:0005524; GO:0005829; GO:0006915; GO:0006954; GO:0042981; GO:0045087 10975 XR_006396441.1 12 4 0 0 0 NA NA NA NA NA NA 10976 XM_044327258.1 10 21 5 11 10 Q96AY4 2.13e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10977 XM_029337548.2 2043 1534 1192 1846 1408 Q6P5D8 6e-82 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 (SMC hinge domain-containing protein 1) (EC 3.6.1.-) Mus musculus (Mouse) chromosome organization [GO:0051276]; dosage compensation by inactivation of X chromosome [GO:0009048]; double-strand break repair [GO:0006302]; inactivation of X chromosome by heterochromatin formation [GO:0060820]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; nose development [GO:0043584]; positive regulation of DNA repair [GO:0045739]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034] GO:0000781; GO:0001740; GO:0003677; GO:0005524; GO:0006302; GO:0009048; GO:0016887; GO:0035861; GO:0042803; GO:0043584; GO:0045739; GO:0051276; GO:0060820; GO:2000042; GO:2001034 10978 XM_029334376.2 0 0 0 0 331 NA NA NA NA NA NA 10979 XM_029352334.2 0 2 10 8 14 NA NA NA NA NA NA 10980 XM_044311382.1 28 23 7 0 0 Q95LR0 2.27e-69 Cilia- and flagella-associated protein 91 (CFAP91) (AMY-1-associating protein expressed in testis 1) (AAT-1) (MYCBP/AMY-1-associated testis-expressed protein 1) (Protein MAATS1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) axonemal central apparatus assembly [GO:1904158]; cell differentiation [GO:0030154]; cilium movement [GO:0003341]; spermatogenesis [GO:0007283] GO:0003341; GO:0005739; GO:0005930; GO:0007283; GO:0030154; GO:0031514; GO:1904158 10981 XM_044314203.1 1004 165 356 776 429 Q80XJ3 4.96e-88 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 10982 XM_044314203.1 1004 165 356 776 429 Q80XJ3 2.18e-84 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 10983 XM_044314203.1 1004 165 356 776 429 Q80XJ3 8.65e-82 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 10984 XM_044314203.1 1004 165 356 776 429 Q80XJ3 4.92e-81 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 10985 XM_044314203.1 1004 165 356 776 429 Q80XJ3 5.24e-79 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 10986 XM_044314203.1 1004 165 356 776 429 Q80XJ3 1.35e-76 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 10987 XM_044314203.1 1004 165 356 776 429 Q80XJ3 2.96e-72 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 10988 XM_044314203.1 1004 165 356 776 429 Q80XJ3 4.08e-52 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 10989 XM_044314203.1 1004 165 356 776 429 Q80XJ3 2.22e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 10990 XM_029347992.2 196 77 242 169 253 P0CI65 2.2e-48 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 10991 XM_029347992.2 196 77 242 169 253 P0CI65 3.02e-46 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 10992 XM_029347992.2 196 77 242 169 253 P0CI65 5.79e-46 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 10993 XM_029347992.2 196 77 242 169 253 P0CI65 5.57e-42 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 10994 XM_029347992.2 196 77 242 169 253 P0CI65 3.09e-34 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 10995 XM_029347992.2 196 77 242 169 253 P0CI65 6.89e-31 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 10996 XR_006391600.1 27 17 20 40 18 NA NA NA NA NA NA 10997 XM_029326862.2 88 42 0 0 106 B8EIZ7 2.9e-103 NA NA NA NA 10998 XR_006395141.1 25 0 40 184 95 NA NA NA NA NA NA 10999 XR_006397832.1 27 15 29 10 57 NA NA NA NA NA NA 11000 XM_029337483.2 814 1031 635 3787 2001 P16065 0 Speract receptor (EC 4.6.1.2) (Guanylate cyclase) Strongylocentrotus purpuratus (Purple sea urchin) cGMP biosynthetic process [GO:0006182]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]; receptor guanylyl cyclase signaling pathway [GO:0007168]; signal transduction [GO:0007165] GO:0001653; GO:0004383; GO:0004672; GO:0005524; GO:0005525; GO:0005886; GO:0006182; GO:0006468; GO:0007165; GO:0007168; GO:0035556 11001 XM_029347169.2 388 758 506 378 593 Q5EAE5 4.78e-52 Josephin-1 (EC 3.4.19.12) (Josephin domain-containing protein 1) Bos taurus (Bovine) protein deubiquitination [GO:0016579] GO:0004843; GO:0005737; GO:0005886; GO:0016579 11002 XM_044314426.1 31 3 14 40 47 NA NA NA NA NA NA 11003 XM_029328300.2 0 0 26 0 0 NA NA NA NA NA NA 11004 XM_029346062.2 0 0 9 0 0 Q8CFK2 3.67e-116 Transcription factor IIIB 90 kDa subunit (TFIIIB90) (mTFIIIB90) (B-related factor 1) (BRF-1) Mus musculus (Mouse) DNA-templated transcription initiation [GO:0006352]; positive regulation of transcription by RNA polymerase III [GO:0045945]; regulation of mRNA stability [GO:0043488]; transcription by RNA polymerase III [GO:0006383]; transcription preinitiation complex assembly [GO:0070897] GO:0000126; GO:0000995; GO:0001006; GO:0005634; GO:0006352; GO:0006383; GO:0017025; GO:0043488; GO:0045945; GO:0046872; GO:0070897; GO:0097550 11005 XM_029349367.2 278 104 98 138 250 Q6ITT3 1.78e-68 Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C (EC 2.4.1.145) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVc) (GnT-IVc) (N-acetylglucosaminyltransferase IVc) (UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVc) Sus scrofa (Pig) protein N-linked glycosylation [GO:0006487] GO:0000139; GO:0006487; GO:0008375; GO:0008454; GO:0046872 11006 XM_029343013.2 1194 811 662 1350 1199 Q6P2K6 0 Serine/threonine-protein phosphatase 4 regulatory subunit 3A (SMEK homolog 1) Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; gluconeogenesis [GO:0006094]; positive regulation of gluconeogenesis [GO:0045722]; protein dephosphorylation [GO:0006470] GO:0005634; GO:0005654; GO:0005737; GO:0005815; GO:0005829; GO:0006094; GO:0006470; GO:0006974; GO:0016607; GO:0030289; GO:0045722; GO:0072542 11007 XM_029346159.2 0 0 0 14 0 Q9EPI9 0 Potassium voltage-gated channel subfamily H member 5 (Ether-a-go-go potassium channel 2) (rEAG2) (Voltage-gated potassium channel subunit Kv10.2) Rattus norvegicus (Rat) potassium ion transmembrane transport [GO:0071805]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391] GO:0005249; GO:0005516; GO:0005886; GO:0009986; GO:0010389; GO:0034765; GO:0042391; GO:0044325; GO:0044877; GO:0071805 11008 XM_044325568.1 4 0 9 13 10 NA NA NA NA NA NA 11009 XM_044307519.1 26 0 3 3 12 O60290 1.36e-34 Zinc finger protein 862 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006355; GO:0046872; GO:0046983 11010 XM_044318433.1 0 0 9 0 7 NA NA NA NA NA NA 11011 XM_044323359.1 625 609 389 565 346 Q08CY9 1.11e-154 EGF domain-specific O-linked N-acetylglucosamine transferase (EC 2.4.1.255) (Extracellular O-linked N-acetylglucosamine transferase) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) protein O-linked glycosylation [GO:0006493] GO:0005788; GO:0006493; GO:0097363 11012 XR_006391873.1 94 32 52 59 70 NA NA NA NA NA NA 11013 XM_044318896.1 554 8 7 253 20 Q9ULJ7 8.98e-52 Ankyrin repeat domain-containing protein 50 Homo sapiens (Human) endocytic recycling [GO:0032456]; protein transport [GO:0015031] GO:0005768; GO:0015031; GO:0032456 11014 XM_044328464.1 8 32 249 10 59 NA NA NA NA NA NA 11015 XM_029348793.2 1245 614 556 1090 1126 NA NA NA NA NA NA 11016 XM_044308435.1 51 0 9 0 41 Q8CGF5 2.77e-54 TLC domain-containing protein 4 (Transmembrane protein 56) Mus musculus (Mouse) lipid homeostasis [GO:0055088] GO:0005783; GO:0016020; GO:0055088 11017 XM_029334698.2 317 167 132 248 163 NA NA NA NA NA NA 11018 XM_044313102.1 0 0 16 0 0 Q9CUX1 7.83e-29 52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (THAP domain-containing protein 0) (THAP domain-containing protein 12) Mus musculus (Mouse) NA GO:0003677; GO:0005634; GO:0046872; GO:0046983 11019 XM_044308491.1 27 0 17 4 5 O93403 5.35e-25 Carbohydrate sulfotransferase 3 (EC 2.8.2.17) (EC 2.8.2.21) (Chondroitin 6-O-sulfotransferase 1) (C6ST-1) (Nervous system involved sulfotransferase) Tetronarce californica (Pacific electric ray) (Torpedo californica) carbohydrate metabolic process [GO:0005975]; chondroitin sulfate biosynthetic process [GO:0030206] GO:0000139; GO:0005975; GO:0008459; GO:0030206 11020 XM_029333621.2 42 0 29 101 57 P16066 6.22e-66 Atrial natriuretic peptide receptor 1 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type A) (ANP-A) (ANPR-A) (NPR-A) (Guanylate cyclase A) (GC-A) Homo sapiens (Human) blood vessel diameter maintenance [GO:0097746]; body fluid secretion [GO:0007589]; cell surface receptor signaling pathway [GO:0007166]; cGMP biosynthetic process [GO:0006182]; cGMP-mediated signaling [GO:0019934]; dopamine metabolic process [GO:0042417]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell growth [GO:0030308]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of cGMP-mediated signaling [GO:0010753]; positive regulation of renal sodium excretion [GO:0035815]; positive regulation of urine volume [GO:0035810]; protein phosphorylation [GO:0006468]; receptor guanylyl cyclase signaling pathway [GO:0007168]; regulation of blood pressure [GO:0008217]; regulation of vascular permeability [GO:0043114]; signal transduction [GO:0007165] GO:0001653; GO:0004383; GO:0004672; GO:0005524; GO:0005525; GO:0005886; GO:0006182; GO:0006468; GO:0007165; GO:0007166; GO:0007168; GO:0007589; GO:0008217; GO:0008528; GO:0010753; GO:0016525; GO:0016941; GO:0017046; GO:0019934; GO:0030308; GO:0035810; GO:0035815; GO:0042417; GO:0042562; GO:0043114; GO:0043235; GO:0048662; GO:0097746; GO:1990620 11021 XM_044327592.1 3230 1450 1668 3266 4088 P46940 0 Ras GTPase-activating-like protein IQGAP1 (p195) Homo sapiens (Human) cell migration [GO:0016477]; cellular response to calcium ion [GO:0071277]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast migration [GO:0010761]; negative regulation of dephosphorylation [GO:0035305]; neuron projection extension [GO:1990138]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; podocyte development [GO:0072015]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein kinase activity [GO:0045860]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cytokine production [GO:0001817]; regulation of GTPase activity [GO:0043087]; regulation of mitotic cell cycle [GO:0007346]; signal transduction [GO:0007165] GO:0001726; GO:0001817; GO:0005078; GO:0005095; GO:0005096; GO:0005509; GO:0005516; GO:0005547; GO:0005634; GO:0005737; GO:0005829; GO:0005874; GO:0005884; GO:0005886; GO:0005925; GO:0007165; GO:0007173; GO:0007346; GO:0008543; GO:0010761; GO:0016323; GO:0016324; GO:0016328; GO:0016477; GO:0019901; GO:0019903; GO:0019904; GO:0030424; GO:0030426; GO:0030496; GO:0030667; GO:0030864; GO:0031234; GO:0031267; GO:0032956; GO:0035305; GO:0036057; GO:0036120; GO:0036464; GO:0043005; GO:0043087; GO:0043410; GO:0043539; GO:0044548; GO:0045296; GO:0045860; GO:0048008; GO:0051015; GO:0060090; GO:0070062; GO:0071277; GO:0071364; GO:0072015; GO:1990138; GO:1990904 11022 XM_029324203.2 991 961 600 768 918 Q8CBC7 5.15e-127 NA NA NA NA 11023 XM_044307980.1 61 99 17 44 6 NA NA NA NA NA NA 11024 XR_006392307.1 40 29 43 26 59 NA NA NA NA NA NA 11025 XM_044324072.1 18 26 125 0 129 NA NA NA NA NA NA 11026 XM_044319562.1 0 0 17 0 0 NA NA NA NA NA NA 11027 XM_029328734.2 593 232 467 557 523 P55937 9.9e-29 Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2) Mus musculus (Mouse) cell differentiation [GO:0030154]; spermatogenesis [GO:0007283] GO:0000139; GO:0005654; GO:0005730; GO:0005793; GO:0005794; GO:0005829; GO:0007283; GO:0030154; GO:0032580; GO:0090498 11028 XM_029338319.2 65 18 0 23 24 NA NA NA NA NA NA 11029 XM_029327430.2 1754 1168 1049 1109 1320 Q9P202 8.02e-34 Whirlin (Autosomal recessive deafness type 31 protein) Homo sapiens (Human) auditory receptor cell stereocilium organization [GO:0060088]; cerebellar Purkinje cell layer formation [GO:0021694]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; inner ear receptor cell differentiation [GO:0060113]; inner ear receptor cell stereocilium organization [GO:0060122]; paranodal junction maintenance [GO:1990227]; positive regulation of gene expression [GO:0010628]; retina homeostasis [GO:0001895]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605] GO:0001895; GO:0001917; GO:0002141; GO:0002142; GO:0005737; GO:0005884; GO:0005886; GO:0005929; GO:0007605; GO:0010628; GO:0021694; GO:0030426; GO:0032391; GO:0032420; GO:0032426; GO:0036064; GO:0042802; GO:0045184; GO:0045202; GO:0050910; GO:0050953; GO:0051649; GO:0060088; GO:0060113; GO:0060122; GO:1990075; GO:1990227; GO:1990696 11030 XM_029332103.2 457 357 287 265 387 NA NA NA NA NA NA 11031 XM_044328440.1 303 191 336 189 305 O88427 0 Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage-gated calcium channel subunit alpha Cav3.2) Mus musculus (Mouse) aldosterone biosynthetic process [GO:0032342]; calcium ion import [GO:0070509]; calcium ion transport [GO:0006816]; cortisol biosynthetic process [GO:0034651]; inorganic cation transmembrane transport [GO:0098662]; membrane depolarization during action potential [GO:0086010]; neuronal action potential [GO:0019228]; positive regulation of acrosome reaction [GO:2000344]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of cardiac muscle cell contraction [GO:0106134]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; sensory perception of pain [GO:0019233] GO:0001518; GO:0005244; GO:0005248; GO:0005634; GO:0005737; GO:0005886; GO:0005891; GO:0005901; GO:0006816; GO:0008332; GO:0016020; GO:0019228; GO:0019233; GO:0030425; GO:0032342; GO:0034651; GO:0034765; GO:0042383; GO:0042391; GO:0043005; GO:0043204; GO:0045211; GO:0045956; GO:0046872; GO:0048787; GO:0070509; GO:0086010; GO:0097110; GO:0098662; GO:0098978; GO:0106134; GO:2000344 11032 XM_044328440.1 303 191 336 189 305 O88427 2.16e-74 Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage-gated calcium channel subunit alpha Cav3.2) Mus musculus (Mouse) aldosterone biosynthetic process [GO:0032342]; calcium ion import [GO:0070509]; calcium ion transport [GO:0006816]; cortisol biosynthetic process [GO:0034651]; inorganic cation transmembrane transport [GO:0098662]; membrane depolarization during action potential [GO:0086010]; neuronal action potential [GO:0019228]; positive regulation of acrosome reaction [GO:2000344]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of cardiac muscle cell contraction [GO:0106134]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; sensory perception of pain [GO:0019233] GO:0001518; GO:0005244; GO:0005248; GO:0005634; GO:0005737; GO:0005886; GO:0005891; GO:0005901; GO:0006816; GO:0008332; GO:0016020; GO:0019228; GO:0019233; GO:0030425; GO:0032342; GO:0034651; GO:0034765; GO:0042383; GO:0042391; GO:0043005; GO:0043204; GO:0045211; GO:0045956; GO:0046872; GO:0048787; GO:0070509; GO:0086010; GO:0097110; GO:0098662; GO:0098978; GO:0106134; GO:2000344 11033 XM_044328861.1 8 0 0 0 1 NA NA NA NA NA NA 11034 XR_006392456.1 17 0 16 155 0 NA NA NA NA NA NA 11035 XR_006397172.1 0 0 0 0 113 NA NA NA NA NA NA 11036 XM_029330992.2 181 52 97 125 165 Q4KLY0 9.4e-57 Centrosomal protein of 63 kDa (Cep63) Rattus norvegicus (Rat) cell division [GO:0051301]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; de novo centriole assembly involved in multi-ciliated epithelial cell differentiation [GO:0098535]; DNA damage checkpoint signaling [GO:0000077]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; meiotic telomere clustering [GO:0045141]; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902254]; protein localization to centrosome [GO:0071539]; reciprocal meiotic recombination [GO:0007131]; signal transduction in response to DNA damage [GO:0042770]; spindle assembly [GO:0051225] GO:0000077; GO:0000922; GO:0005737; GO:0005813; GO:0005814; GO:0007099; GO:0007131; GO:0042770; GO:0045141; GO:0051225; GO:0051298; GO:0051301; GO:0071539; GO:0072332; GO:0098535; GO:1902254 11037 XR_006397170.1 51 27 30 34 127 NA NA NA NA NA NA 11038 XM_029330052.2 13 6 25 14 37 NA NA NA NA NA NA 11039 XM_029358751.2 389 189 219 320 433 D4AR77 1.45e-27 Uncharacterized secreted protein ARB_06907 Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton mentagrophytes) proteolysis [GO:0006508] GO:0005576; GO:0006508; GO:0008236 11040 XM_044328507.1 18 434 14 62 7 NA NA NA NA NA NA 11041 XM_029350859.2 518 169 137 499 206 P52569 4.69e-145 Cationic amino acid transporter 2 (CAT-2) (CAT2) (Low affinity cationic amino acid transporter 2) (Solute carrier family 7 member 2) Homo sapiens (Human) amino acid import across plasma membrane [GO:0089718]; amino acid transport [GO:0006865]; L-alpha-amino acid transmembrane transport [GO:1902475]; L-amino acid transport [GO:0015807]; L-arginine import across plasma membrane [GO:0097638]; L-arginine transmembrane transport [GO:1903826]; L-ornithine transmembrane transport [GO:1903352]; transport across blood-brain barrier [GO:0150104] GO:0000064; GO:0005886; GO:0006865; GO:0015171; GO:0015174; GO:0015179; GO:0015189; GO:0015807; GO:0030054; GO:0061459; GO:0089718; GO:0097638; GO:0150104; GO:1902475; GO:1903352; GO:1903826 11042 XM_029344268.2 0 0 0 0 10 NA NA NA NA NA NA 11043 XM_044325184.1 1069 736 146 900 915 Q32PZ3 0 Protein unc-45 homolog A (Unc-45A) (Smooth muscle cell-associated protein 1) (SMAP-1) Rattus norvegicus (Rat) cell differentiation [GO:0030154]; chaperone-mediated protein folding [GO:0061077]; muscle organ development [GO:0007517] GO:0005634; GO:0005737; GO:0007517; GO:0030154; GO:0048471; GO:0051879; GO:0061077 11044 XM_044327024.1 61 21 82 21 273 NA NA NA NA NA NA 11045 XM_029325141.2 0 118 0 0 0 Q8C206 3.93e-26 G-protein coupled receptor 157 Mus musculus (Mouse) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; circadian behavior [GO:0048512]; G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; radial glial cell differentiation [GO:0060019] GO:0004930; GO:0005886; GO:0007166; GO:0007186; GO:0007189; GO:0048512; GO:0051482; GO:0060019; GO:0060170 11046 XM_029341783.2 46 38 10 13 4 Q75ZP8 4.63e-116 Pyranose 2-oxidase (P2Ox) (POD) (POx) (PROD) (Pyranose oxidase) (EC 1.1.3.10) (FAD-oxidoreductase) (Glucose 2-oxidase) (Pyranose:oxygen 2-oxidoreductase) Lyophyllum shimeji (Hon-shimeji) (Tricholoma shimeji) NA GO:0050233; GO:0050660 11047 XM_044326117.1 59 13 9 21 204 NA NA NA NA NA NA 11048 XM_044316256.1 191 134 360 152 148 Q9H2W6 1.75e-30 39S ribosomal protein L46, mitochondrial (L46mt) (MRP-L46) (Mitochondrial large ribosomal subunit protein mL46) (P2ECSL) Homo sapiens (Human) mitochondrial translation [GO:0032543] GO:0003735; GO:0005654; GO:0005739; GO:0005743; GO:0005762; GO:0030054; GO:0032543 11049 XM_029356822.2 0 0 54 0 0 O54975 0 Xaa-Pro aminopeptidase 1 (EC 3.4.11.9) (Aminoacylproline aminopeptidase) (Cytosolic aminopeptidase P) (Soluble aminopeptidase P) (sAmp) (X-Pro aminopeptidase 1) (X-prolyl aminopeptidase 1, soluble) Rattus norvegicus (Rat) bradykinin catabolic process [GO:0010815]; proteolysis [GO:0006508] GO:0004177; GO:0005737; GO:0005829; GO:0006508; GO:0010815; GO:0030145; GO:0042803; GO:0070006 11050 XM_044307671.1 42 0 53 11 95 NA NA NA NA NA NA 11051 XM_044319812.1 0 2 0 3 46 Q2KHY5 4.02e-36 Fanconi anemia core complex-associated protein 24 (Fanconi anemia-associated protein of 24 kDa) Bos taurus (Bovine) interstrand cross-link repair [GO:0036297] GO:0000785; GO:0003677; GO:0003682; GO:0005654; GO:0036297; GO:0043240; GO:0071821 11052 XM_044310806.1 26 5 10 6 10 NA NA NA NA NA NA 11053 XM_044322972.1 19 1 5 8 10 P59083 1.77e-32 14 kDa phosphohistidine phosphatase (EC 3.9.1.3) (Phosphohistidine phosphatase 1) (PHPT1) (Protein histidine phosphatase) (PHP) Sus scrofa (Pig) peptidyl-histidine dephosphorylation [GO:0035971] GO:0005829; GO:0035971; GO:0101006 11054 XM_029334298.2 44 56 20 205 345 NA NA NA NA NA NA 11055 XM_044307798.1 139 0 0 19 110 Q7RTR2 1.18e-49 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11056 XM_044307798.1 139 0 0 19 110 Q7RTR2 2.42e-49 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11057 XM_044307798.1 139 0 0 19 110 Q7RTR2 1.69e-48 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11058 XM_044307798.1 139 0 0 19 110 Q7RTR2 2.64e-45 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11059 XM_044307798.1 139 0 0 19 110 Q7RTR2 5.5e-42 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11060 XM_044307798.1 139 0 0 19 110 Q7RTR2 2.02e-36 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11061 XM_044307798.1 139 0 0 19 110 Q7RTR2 3.41e-31 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11062 XM_044326547.1 96 42 146 129 429 NA NA NA NA NA NA 11063 XM_044322446.1 10 0 0 0 0 NA NA NA NA NA NA 11064 XM_044324855.1 25 172 461 417 23 Q58A42 8.02e-74 Protein DD3-3 Dictyostelium discoideum (Social amoeba) NA GO:0016020 11065 XM_029355811.1 729 1726 697 828 414 NA NA NA NA NA NA 11066 XM_044325457.1 41 16 27 24 49 Q21355 3.31e-25 Glutathione S-transferase 4 (EC 2.5.1.18) (CeGST1) (GST class-sigma) Caenorhabditis elegans glutathione metabolic process [GO:0006749] GO:0004364; GO:0006749; GO:0043292 11067 XM_044324203.1 35 47 17 45 137 NA NA NA NA NA NA 11068 XM_029324387.2 1606 2005 1527 3579 3325 NA NA NA NA NA NA 11069 XR_006391632.1 399 288 241 221 400 NA NA NA NA NA NA 11070 XM_029333725.2 0 0 0 0 11 NA NA NA NA NA NA 11071 XR_006394957.1 47 64 22 26 29 NA NA NA NA NA NA 11072 XM_029338086.2 217 519 206 590 669 Q9Y385 4.15e-84 Ubiquitin-conjugating enzyme E2 J1 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme J1) (Non-canonical ubiquitin-conjugating enzyme 1) (NCUBE-1) (Yeast ubiquitin-conjugating enzyme UBC6 homolog E) (HsUBC6e) Homo sapiens (Human) negative regulation of retrograde protein transport, ER to cytosol [GO:1904153]; protein N-linked glycosylation via asparagine [GO:0018279]; protein polyubiquitination [GO:0000209]; regulation of macrophage cytokine production [GO:0010935]; regulation of tumor necrosis factor production [GO:0032680]; spermatid development [GO:0007286]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0000209; GO:0005524; GO:0005634; GO:0005789; GO:0007286; GO:0010935; GO:0018279; GO:0030433; GO:0031625; GO:0032680; GO:0061631; GO:1904153 11073 XM_044308406.1 12 16 23 67 38 NA NA NA NA NA NA 11074 XR_006394657.1 23 0 0 0 28 NA NA NA NA NA NA 11075 XM_029323724.2 52 33 30 59 88 Q6DJM2 7.75e-95 Phosphatidate cytidylyltransferase, mitochondrial (EC 2.7.7.41) (CDP-diacylglycerol synthase) (CDP-DAG synthase) (Mitochondrial translocator assembly and maintenance protein 41 homolog) (TAM41) Xenopus laevis (African clawed frog) cardiolipin biosynthetic process [GO:0032049]; CDP-diacylglycerol biosynthetic process [GO:0016024] GO:0004605; GO:0005743; GO:0016024; GO:0019898; GO:0031314; GO:0032049 11076 XM_044311020.1 147 191 165 185 394 Q9UJG1 6.19e-48 Motile sperm domain-containing protein 1 Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000122; GO:0000139; GO:0005634; GO:0005737; GO:0005789; GO:0030154; GO:0045944; GO:0048471 11077 XM_044318877.1 243 0 0 0 424 NA NA NA NA NA NA 11078 XM_044320661.1 0 0 0 1 16 Q60847 5e-22 Collagen alpha-1(XII) chain Mus musculus (Mouse) cell adhesion [GO:0007155]; endodermal cell differentiation [GO:0035987] GO:0005595; GO:0005615; GO:0007155; GO:0035987; GO:0062023 11079 XM_044316199.1 28 47 63 54 245 NA NA NA NA NA NA 11080 XM_044306823.1 200 37 77 133 265 NA NA NA NA NA NA 11081 XM_029354487.2 33 118 90 32 33 Q7SYM0 9.68e-107 Uridine-cytidine kinase 2-A (UCK 2-A) (EC 2.7.1.48) (Cytidine monophosphokinase 2-A) (Uridine monophosphokinase 2-A) Danio rerio (Zebrafish) (Brachydanio rerio) CTP salvage [GO:0044211]; phosphorylation [GO:0016310]; UMP salvage [GO:0044206] GO:0004849; GO:0005524; GO:0005737; GO:0005829; GO:0016310; GO:0043771; GO:0044206; GO:0044211 11082 XM_029341436.2 47 0 12 136 145 NA NA NA NA NA NA 11083 XM_029337565.2 112 93 62 151 124 NA NA NA NA NA NA 11084 XM_044313987.1 318 270 161 237 431 NA NA NA NA NA NA 11085 XM_029346233.2 1034 597 726 845 1151 P27545 7.85e-64 Ceramide synthase 1 (CerS1) (Longevity assurance gene 1 protein homolog 1) (Protein UOG-1) (Sphingoid base N-stearoyltransferase CERS1) (EC 2.3.1.299) Mus musculus (Mouse) brain development [GO:0007420]; cellular response to dithiothreitol [GO:0072721]; cellular response to mycotoxin [GO:0036146]; cellular response to UV-A [GO:0071492]; cellular response to xenobiotic stimulus [GO:0071466]; ceramide biosynthetic process [GO:0046513]; negative regulation of glucose import [GO:0046325]; negative regulation of telomerase activity [GO:0051974]; positive regulation of mitophagy [GO:1901526]; sphingolipid biosynthetic process [GO:0030148] GO:0005783; GO:0005789; GO:0007420; GO:0016410; GO:0030148; GO:0036146; GO:0043231; GO:0046325; GO:0046513; GO:0050291; GO:0051974; GO:0071466; GO:0071492; GO:0072721; GO:1901526 11086 XM_044327820.1 9 5 0 8 4 NA NA NA NA NA NA 11087 XM_029331919.2 0 0 5 0 38 Q7LGC8 1.08e-28 Carbohydrate sulfotransferase 3 (EC 2.8.2.17) (EC 2.8.2.21) (Chondroitin 6-O-sulfotransferase 1) (C6ST-1) (Chondroitin 6-sulfotransferase) (C6ST) (Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 0) (GST-0) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; chondroitin sulfate biosynthetic process [GO:0030206]; N-acetylglucosamine metabolic process [GO:0006044]; sulfur compound metabolic process [GO:0006790]; T cell homeostasis [GO:0043029] GO:0000139; GO:0001517; GO:0005802; GO:0005975; GO:0006044; GO:0006790; GO:0008459; GO:0030206; GO:0043029; GO:0050698 11088 XM_044318430.1 18 7 17 117 42 NA NA NA NA NA NA 11089 XR_006395785.1 7 1 23 5 118 NA NA NA NA NA NA 11090 XM_044315078.1 34713 37744 14246 32370 21795 NA NA NA NA NA NA 11091 XM_044326180.1 8 0 0 0 0 NA NA NA NA NA NA 11092 XM_044317963.1 2717 1670 196 2197 671 NA NA NA NA NA NA 11093 XM_029329287.2 735 569 456 435 458 Q5I0C4 5.13e-41 Protein ABHD14A (EC 3.-.-.-) (Alpha/beta hydrolase domain-containing protein 14A) (Abhydrolase domain-containing protein 14A) Rattus norvegicus (Rat) NA GO:0005737; GO:0016020; GO:0016787 11094 XM_029338213.2 207 56 59 169 179 P42893 5.3e-121 Endothelin-converting enzyme 1 (ECE-1) (EC 3.4.24.71) Rattus norvegicus (Rat) apoptotic process [GO:0006915]; axonogenesis involved in innervation [GO:0060385]; blood vessel diameter maintenance [GO:0097746]; bradykinin catabolic process [GO:0010815]; calcitonin catabolic process [GO:0010816]; ear development [GO:0043583]; embryonic digit morphogenesis [GO:0042733]; embryonic heart tube development [GO:0035050]; endothelin maturation [GO:0034959]; gene expression [GO:0010467]; heart development [GO:0007507]; hormone catabolic process [GO:0042447]; neuron projection development [GO:0031175]; peptide hormone processing [GO:0016486]; pharyngeal system development [GO:0060037]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of receptor recycling [GO:0001921]; protein processing [GO:0016485]; regulation of blood pressure [GO:0008217]; regulation of ERK1 and ERK2 cascade [GO:0070372]; response to cadmium ion [GO:0046686]; response to hypoxia [GO:0001666]; response to muscle stretch [GO:0035994]; response to xenobiotic stimulus [GO:0009410]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; substance P catabolic process [GO:0010814]; sympathetic neuron axon guidance [GO:0097492] GO:0001666; GO:0001921; GO:0004175; GO:0004222; GO:0005768; GO:0005769; GO:0005886; GO:0006915; GO:0007507; GO:0008217; GO:0008270; GO:0009410; GO:0009897; GO:0010467; GO:0010613; GO:0010814; GO:0010815; GO:0010816; GO:0016020; GO:0016485; GO:0016486; GO:0030141; GO:0031175; GO:0031410; GO:0031982; GO:0033093; GO:0034959; GO:0035050; GO:0035994; GO:0042447; GO:0042733; GO:0042802; GO:0042803; GO:0043583; GO:0043950; GO:0045745; GO:0046686; GO:0048471; GO:0060037; GO:0060385; GO:0070372; GO:0097492; GO:0097746; GO:1902287 11095 XM_029348905.2 2745 2058 1684 3222 3705 Q29504 0 Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Ubiquitin-activating enzyme E1) Oryctolagus cuniculus (Rabbit) NA GO:0004839; GO:0005524; GO:0005634; GO:0005737; GO:0005739 11096 XM_029335423.2 0 0 0 14 0 NA NA NA NA NA NA 11097 XM_044325377.1 336 295 264 273 375 NA NA NA NA NA NA 11098 XR_006393983.1 868 1070 558 465 785 NA NA NA NA NA NA 11099 XM_029334824.2 462 803 580 453 487 P00918 8.32e-73 Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase C) (CAC) (Carbonic anhydrase II) (CA-II) (Cyanamide hydratase CA2) (EC 4.2.1.69) Homo sapiens (Human) angiotensin-activated signaling pathway [GO:0038166]; carbon dioxide transport [GO:0015670]; morphogenesis of an epithelium [GO:0002009]; neuron cellular homeostasis [GO:0070050]; one-carbon metabolic process [GO:0006730]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; secretion [GO:0046903] GO:0002009; GO:0004064; GO:0004089; GO:0005737; GO:0005829; GO:0005886; GO:0006730; GO:0008270; GO:0015670; GO:0016836; GO:0018820; GO:0032230; GO:0032849; GO:0038166; GO:0043209; GO:0044070; GO:0045177; GO:0046903; GO:0051453; GO:0070050; GO:0070062; GO:2001150; GO:2001225 11100 XM_044315747.1 0 37 0 0 0 A0A0R4IC37 0 Cleavage and polyadenylation specificity factor subunit 1 (Cleavage and polyadenylation specific factor 1) Danio rerio (Zebrafish) (Brachydanio rerio) definitive hemopoiesis [GO:0060216]; mRNA polyadenylation [GO:0006378]; retinal ganglion cell axon guidance [GO:0031290] GO:0003676; GO:0005634; GO:0005654; GO:0005847; GO:0006378; GO:0031290; GO:0060216 11101 XM_029339062.2 1692 891 880 1684 2490 Q9Z1G4 0 V-type proton ATPase 116 kDa subunit a 1 (V-ATPase 116 kDa subunit a 1) (Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit) (Vacuolar adenosine triphosphatase subunit Ac116) (Vacuolar proton pump subunit 1) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1) Mus musculus (Mouse) regulation of macroautophagy [GO:0016241]; synaptic vesicle lumen acidification [GO:0097401]; toxin transport [GO:1901998]; vacuolar acidification [GO:0007035] GO:0000220; GO:0005737; GO:0005794; GO:0005829; GO:0005886; GO:0007035; GO:0008021; GO:0016020; GO:0016241; GO:0016471; GO:0016607; GO:0030665; GO:0030672; GO:0042470; GO:0043229; GO:0043231; GO:0046961; GO:0048471; GO:0051117; GO:0097401; GO:1901998 11102 XR_006393967.1 0 0 0 0 18 NA NA NA NA NA NA 11103 XM_044323143.1 149 15 69 38 0 NA NA NA NA NA NA 11104 XR_006393001.1 41 2 25 5 151 NA NA NA NA NA NA 11105 XM_044328671.1 0 62 415 0 300 Q6V0K7 7.72e-50 Oncoprotein-induced transcript 3 protein (Liver-specific zona pellucida domain-containing protein) Rattus norvegicus (Rat) urate homeostasis [GO:1903118] GO:0005201; GO:0005509; GO:0005615; GO:0005635; GO:0009986; GO:1903118 11106 XM_029339339.2 2452 2273 1764 2242 1785 Q6P5I8 2.78e-75 Protein YIPF5 (YIP1 family member 5) Danio rerio (Zebrafish) (Brachydanio rerio) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; protein transport [GO:0015031]; regulation of ER to Golgi vesicle-mediated transport [GO:0060628]; vesicle fusion with Golgi apparatus [GO:0048280] GO:0005789; GO:0005802; GO:0006888; GO:0015031; GO:0048280; GO:0060628 11107 XM_029336650.2 694 361 160 460 332 NA NA NA NA NA NA 11108 XM_044312219.1 5 17 8 5 10 NA NA NA NA NA NA 11109 XM_044321896.1 46 0 5 0 34 Q9GZQ4 4.52e-22 Neuromedin-U receptor 2 (NMU-R2) (G-protein coupled receptor FM-4) (G-protein coupled receptor TGR-1) Homo sapiens (Human) arachidonic acid secretion [GO:0050482]; calcium ion transport [GO:0006816]; calcium-mediated signaling [GO:0019722]; cell-cell signaling [GO:0007267]; central nervous system development [GO:0007417]; feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; grooming behavior [GO:0007625]; inositol phosphate-mediated signaling [GO:0048016]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; reduction of food intake in response to dietary excess [GO:0002023]; regulation of sensory perception of pain [GO:0051930]; regulation of smooth muscle contraction [GO:0006940]; response to pain [GO:0048265] GO:0001607; GO:0002023; GO:0004930; GO:0005229; GO:0005525; GO:0005886; GO:0006816; GO:0006940; GO:0007186; GO:0007200; GO:0007204; GO:0007218; GO:0007267; GO:0007417; GO:0007625; GO:0007631; GO:0008188; GO:0016020; GO:0019722; GO:0042924; GO:0048016; GO:0048265; GO:0050482; GO:0051930 11110 XM_044320386.1 0 0 0 269 230 Q3UTQ8 2.16e-154 Cyclin-dependent kinase-like 5 (EC 2.7.11.22) Mus musculus (Mouse) modulation of chemical synaptic transmission [GO:0050804]; neuron migration [GO:0001764]; positive regulation of axon extension [GO:0045773]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of GTPase activity [GO:0043547]; protein autophosphorylation [GO:0046777]; protein localization to nucleus [GO:0034504]; protein phosphorylation [GO:0006468]; regulation of cilium assembly [GO:1902017]; regulation of dendrite development [GO:0050773]; regulation of postsynapse organization [GO:0099175] GO:0001764; GO:0004672; GO:0004693; GO:0005524; GO:0005634; GO:0005654; GO:0005813; GO:0006468; GO:0016301; GO:0031267; GO:0032587; GO:0032839; GO:0034504; GO:0036064; GO:0043547; GO:0044294; GO:0045202; GO:0045773; GO:0046777; GO:0048471; GO:0050773; GO:0050775; GO:0050804; GO:0060999; GO:0097542; GO:0098978; GO:0099092; GO:0099175; GO:0106310; GO:1902017 11111 XM_029348749.2 1227 663 673 798 839 A3KGZ2 6.88e-133 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2 (EC 1.14.11.-) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005506; GO:0016705; GO:0031418; GO:0051213 11112 XM_029338669.2 0 0 0 0 76 Q5F413 2.91e-51 Stromal membrane-associated protein 2 (Stromal membrane-associated protein 1-like) Gallus gallus (Chicken) NA GO:0005096; GO:0005737; GO:0046872 11113 XR_003828613.2 278 357 293 369 212 NA NA NA NA NA NA 11114 XM_044317130.1 7 14 0 472 32 NA NA NA NA NA NA 11115 XM_029351842.2 796 39 192 515 514 A5HUI5 0 Aminopeptidase A (AP-A) (APA) (EC 3.4.11.7) (Glutamyl aminopeptidase) (EAP) Gloydius brevicaudus (Korean slamosa snake) (Agkistrodon halys brevicaudus) proteolysis [GO:0006508] GO:0004177; GO:0005886; GO:0006508; GO:0008237; GO:0008270 11116 XM_044328506.1 28 44 83 55 5 Q8K2J9 1.26e-71 BTB/POZ domain-containing protein 6 Mus musculus (Mouse) neurogenesis [GO:0022008] GO:0005829; GO:0022008 11117 XM_029346864.2 2 0 17 2 19 NA NA NA NA NA NA 11118 XM_044324884.1 0 58 0 12 65 NA NA NA NA NA NA 11119 XM_044314875.1 26 61 54 93 82 B8VIU6 6.64e-56 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 11120 XM_044315529.1 121 144 28 0 261 NA NA NA NA NA NA 11121 XM_029358532.2 157 73 140 128 125 NA NA NA NA NA NA 11122 XM_029336973.2 251 390 820 460 266 NA NA NA NA NA NA 11123 XM_044327875.1 68 83 53 43 111 Q6PFL0 7.22e-33 Mediator of RNA polymerase II transcription subunit 27 (Cofactor required for Sp1 transcriptional activation subunit 8) (CRSP complex subunit 8) (Mediator complex subunit 27) Danio rerio (Zebrafish) (Brachydanio rerio) camera-type eye development [GO:0043010]; regulation of transcription by RNA polymerase II [GO:0006357]; retinal cone cell development [GO:0046549] GO:0003713; GO:0006357; GO:0016592; GO:0043010; GO:0046549 11124 XM_029335480.2 11748 9059 6910 9012 10303 Q6GLN5 4.73e-33 NEDD4 family-interacting protein 1 Xenopus laevis (African clawed frog) metal ion transport [GO:0030001]; vacuolar transport [GO:0007034] GO:0000139; GO:0007034; GO:0030001 11125 XM_044325283.1 124 160 243 65 0 Q01484 0 Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin) Homo sapiens (Human) atrial cardiac muscle cell action potential [GO:0086014]; atrial cardiac muscle cell to AV node cell communication [GO:0086066]; atrial septum development [GO:0003283]; cellular calcium ion homeostasis [GO:0006874]; endocytosis [GO:0006897]; membrane depolarization during SA node cell action potential [GO:0086046]; paranodal junction assembly [GO:0030913]; positive regulation of calcium ion transmembrane transporter activity [GO:1901021]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cation channel activity [GO:2001259]; positive regulation of gene expression [GO:0010628]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to endoplasmic reticulum [GO:0070972]; protein localization to M-band [GO:0036309]; protein localization to organelle [GO:0033365]; protein localization to plasma membrane [GO:0072659]; protein localization to T-tubule [GO:0036371]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; regulation of atrial cardiac muscle cell action potential [GO:0098910]; regulation of calcium ion transmembrane transporter activity [GO:1901019]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of heart rate [GO:0002027]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of protein stability [GO:0031647]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of SA node cell action potential [GO:0098907]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; response to methylmercury [GO:0051597]; SA node cell action potential [GO:0086015]; SA node cell to atrial cardiac muscle cell communication [GO:0086070]; sarcoplasmic reticulum calcium ion transport [GO:0070296]; T-tubule organization [GO:0033292]; ventricular cardiac muscle cell action potential [GO:0086005] GO:0002027; GO:0003283; GO:0005200; GO:0005739; GO:0005764; GO:0005769; GO:0005829; GO:0005856; GO:0005886; GO:0006874; GO:0006897; GO:0008093; GO:0008104; GO:0010628; GO:0010881; GO:0010882; GO:0014704; GO:0015031; GO:0016323; GO:0016324; GO:0019899; GO:0019901; GO:0030018; GO:0030315; GO:0030507; GO:0030674; GO:0030913; GO:0031430; GO:0031647; GO:0031672; GO:0033292; GO:0033365; GO:0034394; GO:0036309; GO:0036371; GO:0042383; GO:0043005; GO:0043034; GO:0043268; GO:0044325; GO:0045121; GO:0045211; GO:0050821; GO:0051117; GO:0051279; GO:0051597; GO:0051924; GO:0051928; GO:0055037; GO:0055117; GO:0060307; GO:0070296; GO:0070972; GO:0072659; GO:0086004; GO:0086005; GO:0086014; GO:0086015; GO:0086046; GO:0086066; GO:0086070; GO:0086091; GO:0098907; GO:0098910; GO:0140031; GO:1901018; GO:1901019; GO:1901021; GO:2001259 11126 XM_044325283.1 124 160 243 65 0 Q01484 1.17e-105 Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin) Homo sapiens (Human) atrial cardiac muscle cell action potential [GO:0086014]; atrial cardiac muscle cell to AV node cell communication [GO:0086066]; atrial septum development [GO:0003283]; cellular calcium ion homeostasis [GO:0006874]; endocytosis [GO:0006897]; membrane depolarization during SA node cell action potential [GO:0086046]; paranodal junction assembly [GO:0030913]; positive regulation of calcium ion transmembrane transporter activity [GO:1901021]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cation channel activity [GO:2001259]; positive regulation of gene expression [GO:0010628]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to endoplasmic reticulum [GO:0070972]; protein localization to M-band [GO:0036309]; protein localization to organelle [GO:0033365]; protein localization to plasma membrane [GO:0072659]; protein localization to T-tubule [GO:0036371]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; regulation of atrial cardiac muscle cell action potential [GO:0098910]; regulation of calcium ion transmembrane transporter activity [GO:1901019]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of heart rate [GO:0002027]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of protein stability [GO:0031647]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of SA node cell action potential [GO:0098907]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; response to methylmercury [GO:0051597]; SA node cell action potential [GO:0086015]; SA node cell to atrial cardiac muscle cell communication [GO:0086070]; sarcoplasmic reticulum calcium ion transport [GO:0070296]; T-tubule organization [GO:0033292]; ventricular cardiac muscle cell action potential [GO:0086005] GO:0002027; GO:0003283; GO:0005200; GO:0005739; GO:0005764; GO:0005769; GO:0005829; GO:0005856; GO:0005886; GO:0006874; GO:0006897; GO:0008093; GO:0008104; GO:0010628; GO:0010881; GO:0010882; GO:0014704; GO:0015031; GO:0016323; GO:0016324; GO:0019899; GO:0019901; GO:0030018; GO:0030315; GO:0030507; GO:0030674; GO:0030913; GO:0031430; GO:0031647; GO:0031672; GO:0033292; GO:0033365; GO:0034394; GO:0036309; GO:0036371; GO:0042383; GO:0043005; GO:0043034; GO:0043268; GO:0044325; GO:0045121; GO:0045211; GO:0050821; GO:0051117; GO:0051279; GO:0051597; GO:0051924; GO:0051928; GO:0055037; GO:0055117; GO:0060307; GO:0070296; GO:0070972; GO:0072659; GO:0086004; GO:0086005; GO:0086014; GO:0086015; GO:0086046; GO:0086066; GO:0086070; GO:0086091; GO:0098907; GO:0098910; GO:0140031; GO:1901018; GO:1901019; GO:1901021; GO:2001259 11127 XM_044325283.1 124 160 243 65 0 Q01484 1.1e-103 Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin) Homo sapiens (Human) atrial cardiac muscle cell action potential [GO:0086014]; atrial cardiac muscle cell to AV node cell communication [GO:0086066]; atrial septum development [GO:0003283]; cellular calcium ion homeostasis [GO:0006874]; endocytosis [GO:0006897]; membrane depolarization during SA node cell action potential [GO:0086046]; paranodal junction assembly [GO:0030913]; positive regulation of calcium ion transmembrane transporter activity [GO:1901021]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cation channel activity [GO:2001259]; positive regulation of gene expression [GO:0010628]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to endoplasmic reticulum [GO:0070972]; protein localization to M-band [GO:0036309]; protein localization to organelle [GO:0033365]; protein localization to plasma membrane [GO:0072659]; protein localization to T-tubule [GO:0036371]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; regulation of atrial cardiac muscle cell action potential [GO:0098910]; regulation of calcium ion transmembrane transporter activity [GO:1901019]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of heart rate [GO:0002027]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of protein stability [GO:0031647]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of SA node cell action potential [GO:0098907]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; response to methylmercury [GO:0051597]; SA node cell action potential [GO:0086015]; SA node cell to atrial cardiac muscle cell communication [GO:0086070]; sarcoplasmic reticulum calcium ion transport [GO:0070296]; T-tubule organization [GO:0033292]; ventricular cardiac muscle cell action potential [GO:0086005] GO:0002027; GO:0003283; GO:0005200; GO:0005739; GO:0005764; GO:0005769; GO:0005829; GO:0005856; GO:0005886; GO:0006874; GO:0006897; GO:0008093; GO:0008104; GO:0010628; GO:0010881; GO:0010882; GO:0014704; GO:0015031; GO:0016323; GO:0016324; GO:0019899; GO:0019901; GO:0030018; GO:0030315; GO:0030507; GO:0030674; GO:0030913; GO:0031430; GO:0031647; GO:0031672; GO:0033292; GO:0033365; GO:0034394; GO:0036309; GO:0036371; GO:0042383; GO:0043005; GO:0043034; GO:0043268; GO:0044325; GO:0045121; GO:0045211; GO:0050821; GO:0051117; GO:0051279; GO:0051597; GO:0051924; GO:0051928; GO:0055037; GO:0055117; GO:0060307; GO:0070296; GO:0070972; GO:0072659; GO:0086004; GO:0086005; GO:0086014; GO:0086015; GO:0086046; GO:0086066; GO:0086070; GO:0086091; GO:0098907; GO:0098910; GO:0140031; GO:1901018; GO:1901019; GO:1901021; GO:2001259 11128 XM_044325283.1 124 160 243 65 0 Q01484 1.64e-46 Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin) Homo sapiens (Human) atrial cardiac muscle cell action potential [GO:0086014]; atrial cardiac muscle cell to AV node cell communication [GO:0086066]; atrial septum development [GO:0003283]; cellular calcium ion homeostasis [GO:0006874]; endocytosis [GO:0006897]; membrane depolarization during SA node cell action potential [GO:0086046]; paranodal junction assembly [GO:0030913]; positive regulation of calcium ion transmembrane transporter activity [GO:1901021]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cation channel activity [GO:2001259]; positive regulation of gene expression [GO:0010628]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to endoplasmic reticulum [GO:0070972]; protein localization to M-band [GO:0036309]; protein localization to organelle [GO:0033365]; protein localization to plasma membrane [GO:0072659]; protein localization to T-tubule [GO:0036371]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; regulation of atrial cardiac muscle cell action potential [GO:0098910]; regulation of calcium ion transmembrane transporter activity [GO:1901019]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of heart rate [GO:0002027]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of protein stability [GO:0031647]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of SA node cell action potential [GO:0098907]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; response to methylmercury [GO:0051597]; SA node cell action potential [GO:0086015]; SA node cell to atrial cardiac muscle cell communication [GO:0086070]; sarcoplasmic reticulum calcium ion transport [GO:0070296]; T-tubule organization [GO:0033292]; ventricular cardiac muscle cell action potential [GO:0086005] GO:0002027; GO:0003283; GO:0005200; GO:0005739; GO:0005764; GO:0005769; GO:0005829; GO:0005856; GO:0005886; GO:0006874; GO:0006897; GO:0008093; GO:0008104; GO:0010628; GO:0010881; GO:0010882; GO:0014704; GO:0015031; GO:0016323; GO:0016324; GO:0019899; GO:0019901; GO:0030018; GO:0030315; GO:0030507; GO:0030674; GO:0030913; GO:0031430; GO:0031647; GO:0031672; GO:0033292; GO:0033365; GO:0034394; GO:0036309; GO:0036371; GO:0042383; GO:0043005; GO:0043034; GO:0043268; GO:0044325; GO:0045121; GO:0045211; GO:0050821; GO:0051117; GO:0051279; GO:0051597; GO:0051924; GO:0051928; GO:0055037; GO:0055117; GO:0060307; GO:0070296; GO:0070972; GO:0072659; GO:0086004; GO:0086005; GO:0086014; GO:0086015; GO:0086046; GO:0086066; GO:0086070; GO:0086091; GO:0098907; GO:0098910; GO:0140031; GO:1901018; GO:1901019; GO:1901021; GO:2001259 11129 XM_029327988.2 9 0 5 14 8 NA NA NA NA NA NA 11130 XM_044329197.1 221 149 143 192 165 NA NA NA NA NA NA 11131 XM_044322961.1 973 811 658 867 1082 NA NA NA NA NA NA 11132 XM_044322251.1 205 147 13 178 53 NA NA NA NA NA NA 11133 XM_044325995.1 49 63 0 32 0 A8E7N9 1.08e-39 Growth/differentiation factor 6-B (GDF-6-B) (Growth differentiation factor 6b) (Protein dynamo) Danio rerio (Zebrafish) (Brachydanio rerio) positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; SMAD protein signal transduction [GO:0060395] GO:0005125; GO:0005615; GO:0008083; GO:0010862; GO:0060395 11134 XM_044316386.1 326 181 172 326 486 Q15477 0 SKI2 subunit of superkiller complex protein (Helicase SKI2W) (Ski2) (EC 3.6.4.13) (Helicase-like protein) (HLP) Homo sapiens (Human) nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay [GO:0070478]; RNA catabolic process [GO:0006401] GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005829; GO:0006401; GO:0016887; GO:0055087; GO:0070478 11135 XM_029348093.2 0 39 0 23 11 O89103 3.03e-21 Complement component C1q receptor (C1q/MBL/SPA receptor) (C1qR(p)) (C1qRp) (Cell surface antigen AA4) (Complement component 1 q subcomponent receptor 1) (Lymphocyte antigen 68) (Ly-68) (CD antigen CD93) Mus musculus (Mouse) cell-cell adhesion [GO:0098609] GO:0001849; GO:0005509; GO:0005886; GO:0009986; GO:0030246; GO:0031410; GO:0098609 11136 XM_029344721.2 12 0 2 49 22 O43854 5.67e-48 EGF-like repeat and discoidin I-like domain-containing protein 3 (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1) Homo sapiens (Human) cell adhesion [GO:0007155]; positive regulation of cell-substrate adhesion [GO:0010811] GO:0005178; GO:0005509; GO:0007155; GO:0010811; GO:0062023; GO:0070062; GO:1903561 11137 XM_029344721.2 12 0 2 49 22 O43854 7.52e-45 EGF-like repeat and discoidin I-like domain-containing protein 3 (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1) Homo sapiens (Human) cell adhesion [GO:0007155]; positive regulation of cell-substrate adhesion [GO:0010811] GO:0005178; GO:0005509; GO:0007155; GO:0010811; GO:0062023; GO:0070062; GO:1903561 11138 XM_029344721.2 12 0 2 49 22 O43854 1.54e-29 EGF-like repeat and discoidin I-like domain-containing protein 3 (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1) Homo sapiens (Human) cell adhesion [GO:0007155]; positive regulation of cell-substrate adhesion [GO:0010811] GO:0005178; GO:0005509; GO:0007155; GO:0010811; GO:0062023; GO:0070062; GO:1903561 11139 XM_044310158.1 96 210 471 721 1548 Q9NZJ4 0 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 11140 XM_044310158.1 96 210 471 721 1548 Q9NZJ4 2.11e-31 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 11141 XM_029344274.2 11 30 13 32 55 NA NA NA NA NA NA 11142 XM_029352384.2 194 83 28 42 0 NA NA NA NA NA NA 11143 XR_006396428.1 211 222 185 229 680 NA NA NA NA NA NA 11144 XR_006396786.1 629 462 244 426 332 Q9VX10 1.16e-41 Putative sulfiredoxin (EC 1.8.98.2) Drosophila melanogaster (Fruit fly) cellular oxidant detoxification [GO:0098869]; cellular response to oxidative stress [GO:0034599] GO:0005524; GO:0005737; GO:0005829; GO:0032542; GO:0034599; GO:0098869 11145 XM_029341681.2 1871 1642 1164 1656 1281 Q8MJ44 0 cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11) Canis lupus familiaris (Dog) (Canis familiaris) cellular response to heat [GO:0034605]; protein kinase A signaling [GO:0010737]; protein phosphorylation [GO:0006468] GO:0001669; GO:0004674; GO:0004679; GO:0004691; GO:0005524; GO:0005634; GO:0005737; GO:0005739; GO:0005886; GO:0006468; GO:0010737; GO:0034237; GO:0034605; GO:0036126; GO:0048471; GO:0106310 11146 XM_044320219.1 1028 1126 411 656 588 NA NA NA NA NA NA 11147 XM_044309775.1 16 7 2 26 31 Q9VBW3 5.84e-60 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 11148 XM_029357504.2 660 0 0 491 531 P23824 2.9e-70 GATA-binding factor 2 (GATA-2) (Transcription factor NF-E1b) Gallus gallus (Chicken) cell fate commitment [GO:0045165]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of angiogenesis [GO:0045766]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000122; GO:0000978; GO:0000981; GO:0001223; GO:0005634; GO:0008270; GO:0045165; GO:0045766; GO:0045944; GO:1902895 11149 XM_044318087.1 0 0 0 2 42 NA NA NA NA NA NA 11150 XM_029356088.2 1 546 0 222 779 C8YR32 9.06e-81 Lipoxygenase homology domain-containing protein 1 Mus musculus (Mouse) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 11151 XM_029356088.2 1 546 0 222 779 C8YR32 6.69e-77 Lipoxygenase homology domain-containing protein 1 Mus musculus (Mouse) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 11152 XM_029356088.2 1 546 0 222 779 C8YR32 1.45e-72 Lipoxygenase homology domain-containing protein 1 Mus musculus (Mouse) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 11153 XM_029356088.2 1 546 0 222 779 C8YR32 4.79e-71 Lipoxygenase homology domain-containing protein 1 Mus musculus (Mouse) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 11154 XM_029356088.2 1 546 0 222 779 C8YR32 1.18e-69 Lipoxygenase homology domain-containing protein 1 Mus musculus (Mouse) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 11155 XM_029356088.2 1 546 0 222 779 C8YR32 6.66e-61 Lipoxygenase homology domain-containing protein 1 Mus musculus (Mouse) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 11156 XM_029356088.2 1 546 0 222 779 C8YR32 2.83e-60 Lipoxygenase homology domain-containing protein 1 Mus musculus (Mouse) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 11157 XM_029356088.2 1 546 0 222 779 C8YR32 1.09e-44 Lipoxygenase homology domain-containing protein 1 Mus musculus (Mouse) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 11158 XM_029356088.2 1 546 0 222 779 C8YR32 5.31e-44 Lipoxygenase homology domain-containing protein 1 Mus musculus (Mouse) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 11159 XM_029356088.2 1 546 0 222 779 C8YR32 6.77e-38 Lipoxygenase homology domain-containing protein 1 Mus musculus (Mouse) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 11160 XM_044315721.1 116 34 27 17 147 NA NA NA NA NA NA 11161 XM_044320777.1 18 18 32 0 16 B3EWZ5 5.78e-23 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 11162 XM_044320777.1 18 18 32 0 16 B3EWZ5 1.48e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 11163 XM_044320777.1 18 18 32 0 16 B3EWZ5 4.49e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 11164 XM_044320777.1 18 18 32 0 16 B3EWZ5 5.69e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 11165 XM_029343867.2 25 20 7 46 25 Q2KJC3 2.11e-150 Macrophage-expressed gene 1 protein (Macrophage gene 1 protein) (Mpg-1) (Perforin-2) (P-2) Bos taurus (Bovine) antibacterial innate immune response [GO:0140367]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; disruption by host of symbiont membrane [GO:0052337] GO:0030659; GO:0031410; GO:0042742; GO:0045335; GO:0050829; GO:0050830; GO:0052337; GO:0140367 11166 XM_044310766.1 0 2 0 16 27 NA NA NA NA NA NA 11167 XM_029332304.2 452 252 140 222 330 Q9NP78 0 ABC-type oligopeptide transporter ABCB9 (EC 7.4.2.6) (ATP-binding cassette sub-family B member 9) (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (hABCB9) (TAP-like protein) (TAPL) Homo sapiens (Human) antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; peptide metabolic process [GO:0006518]; peptide transport [GO:0015833]; protein transport [GO:0015031]; transmembrane transport [GO:0055085] GO:0005524; GO:0005764; GO:0005765; GO:0005789; GO:0006518; GO:0015031; GO:0015421; GO:0015433; GO:0015440; GO:0015833; GO:0016020; GO:0016887; GO:0019885; GO:0022857; GO:0042626; GO:0042803; GO:0042824; GO:0043231; GO:0046978; GO:0055085 11168 XM_044322294.1 12 7 4 1 0 NA NA NA NA NA NA 11169 XR_006392275.1 132 28 0 136 171 NA NA NA NA NA NA 11170 XM_029357929.2 107 0 53 139 60 NA NA NA NA NA NA 11171 XM_029333860.2 774 262 357 631 757 Q7TN88 1.01e-64 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 11172 XM_029333860.2 774 262 357 631 757 Q7TN88 2.4e-54 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 11173 XM_044312598.1 144 116 53 94 143 NA NA NA NA NA NA 11174 XM_044316611.1 1540 2287 1030 1729 1306 Q6VGS5 8.48e-67 Protein Daple (Coiled-coil domain-containing protein 88C) (Dvl-associating protein with a high frequency of leucine residues) Mus musculus (Mouse) apical constriction [GO:0003383]; cytoplasmic microtubule organization [GO:0031122]; cytoskeleton-dependent intracellular transport [GO:0030705]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-canonical Wnt signaling pathway [GO:0035567]; protein destabilization [GO:0031648]; regulation of protein phosphorylation [GO:0001932]; small GTPase mediated signal transduction [GO:0007264]; stress-activated protein kinase signaling cascade [GO:0031098] GO:0001932; GO:0001965; GO:0003383; GO:0005085; GO:0005109; GO:0005737; GO:0005813; GO:0005829; GO:0007264; GO:0008017; GO:0030054; GO:0030165; GO:0030705; GO:0031098; GO:0031122; GO:0031648; GO:0035567; GO:0042802; GO:0043621; GO:0051959; GO:0070161; GO:0090090 11175 XR_003828630.2 98 65 109 40 114 NA NA NA NA NA NA 11176 XM_029351493.2 111 97 11 63 10 NA NA NA NA NA NA 11177 XM_029327324.2 686 3194 1294 4117 3363 D9IQ16 3.97e-27 Galaxin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 11178 XM_029327324.2 686 3194 1294 4117 3363 D9IQ16 7.11e-22 Galaxin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 11179 XR_003825086.2 0 0 34 0 0 NA NA NA NA NA NA 11180 XM_044321163.1 162 94 26 59 53 NA NA NA NA NA NA 11181 XM_029352028.2 486 751 355 369 536 B3NDN0 9.98e-81 Kelch-like protein diablo Drosophila erecta (Fruit fly) negative regulation of synaptic assembly at neuromuscular junction [GO:0045886]; protein autoubiquitination [GO:0051865] GO:0003779; GO:0042803; GO:0045886; GO:0051865 11182 XM_029352028.2 486 751 355 369 536 B3NDN0 1.55e-26 Kelch-like protein diablo Drosophila erecta (Fruit fly) negative regulation of synaptic assembly at neuromuscular junction [GO:0045886]; protein autoubiquitination [GO:0051865] GO:0003779; GO:0042803; GO:0045886; GO:0051865 11183 XM_029335087.2 7 3 7 6 17 NA NA NA NA NA NA 11184 XR_003824466.2 3 0 69 57 11 NA NA NA NA NA NA 11185 XR_003828615.2 6 4 0 5 1 NA NA NA NA NA NA 11186 XM_044310857.1 1349 2012 1216 2438 315 Q7RTR2 2.09e-48 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11187 XM_044310857.1 1349 2012 1216 2438 315 Q7RTR2 8.5e-48 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11188 XM_044310857.1 1349 2012 1216 2438 315 Q7RTR2 1.71e-47 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11189 XM_044310857.1 1349 2012 1216 2438 315 Q7RTR2 1.11e-43 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11190 XM_044310857.1 1349 2012 1216 2438 315 Q7RTR2 6.02e-43 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11191 XM_044310857.1 1349 2012 1216 2438 315 Q7RTR2 4.66e-33 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11192 XM_044324585.1 0 0 0 1 58 NA NA NA NA NA NA 11193 XR_003822944.2 51 6 46 29 22 Q8VEJ1 2.82e-141 GPN-loop GTPase 2 (ATP-binding domain 1 family member B) Mus musculus (Mouse) NA GO:0003924; GO:0005525 11194 XM_029350514.2 3139 2559 1178 2391 2420 Q8VI63 1.51e-54 MOB kinase activator 2 (Mob2 homolog) (Mps one binder kinase activator-like 2) (Ovary-specific MOB-like protein) Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein phosphorylation [GO:0001934]; signal transduction [GO:0007165] GO:0001934; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0007165; GO:0010976; GO:0030036; GO:0030295; GO:0044306; GO:0046872; GO:0048471 11195 XM_029337719.2 20 13 44 7 0 NA NA NA NA NA NA 11196 XM_044319851.1 19 0 0 0 60 NA NA NA NA NA NA 11197 XR_006396623.1 0 0 20 0 0 NA NA NA NA NA NA 11198 XM_029327331.2 87 93 31 62 67 A6YP92 2.98e-34 Homeobox protein ARX (Aristaless-related homeobox) Rattus norvegicus (Rat) axon guidance [GO:0007411]; brain development [GO:0007420]; cell proliferation in forebrain [GO:0021846]; cerebral cortex GABAergic interneuron migration [GO:0021853]; cerebral cortex tangential migration [GO:0021800]; embryonic olfactory bulb interneuron precursor migration [GO:0021831]; enteric nervous system development [GO:0048484]; epithelial cell fate commitment [GO:0072148]; forebrain development [GO:0030900]; globus pallidus development [GO:0021759]; interneuron migration [GO:1904936]; lipid digestion [GO:0044241]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron development [GO:0048666]; neuron migration [GO:0001764]; olfactory bulb development [GO:0021772]; organ growth [GO:0035265]; positive regulation of gene expression [GO:0010628]; positive regulation of organ growth [GO:0046622]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell population proliferation [GO:0042127]; regulation of epithelial cell proliferation [GO:0050678]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000977; GO:0000978; GO:0000981; GO:0001227; GO:0001228; GO:0001764; GO:0003682; GO:0005634; GO:0006357; GO:0007411; GO:0007420; GO:0010628; GO:0021759; GO:0021772; GO:0021800; GO:0021831; GO:0021846; GO:0021853; GO:0030900; GO:0035265; GO:0042127; GO:0044241; GO:0045944; GO:0046622; GO:0048484; GO:0048666; GO:0050678; GO:0072148; GO:1904936; GO:1990837 11199 XM_044312462.1 4 16 26 17 14 NA NA NA NA NA NA 11200 XM_044326733.1 62 15 36 14 22 Q96AY4 2.02e-165 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11201 XM_044326733.1 62 15 36 14 22 Q96AY4 1.26e-157 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11202 XM_044326733.1 62 15 36 14 22 Q96AY4 1.42e-154 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11203 XM_044326733.1 62 15 36 14 22 Q96AY4 4.14e-149 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11204 XM_044326733.1 62 15 36 14 22 Q96AY4 1.92e-144 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11205 XM_044326733.1 62 15 36 14 22 Q96AY4 2.28e-135 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11206 XM_044326733.1 62 15 36 14 22 Q96AY4 1e-110 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11207 XM_044326733.1 62 15 36 14 22 Q96AY4 2.96e-62 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11208 XM_044326733.1 62 15 36 14 22 Q96AY4 1.3e-54 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11209 XM_044326733.1 62 15 36 14 22 Q96AY4 7.94e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11210 XM_029343711.2 86 10 18 45 234 NA NA NA NA NA NA 11211 XM_029334342.2 67 123 104 82 184 NA NA NA NA NA NA 11212 XR_003827898.2 23 7 0 0 0 NA NA NA NA NA NA 11213 XR_006392492.1 0 5 0 33 2 NA NA NA NA NA NA 11214 XM_044318263.1 0 106 6 0 0 P31422 0 Metabotropic glutamate receptor 3 (mGluR3) Rattus norvegicus (Rat) G protein-coupled glutamate receptor signaling pathway [GO:0007216]; gene expression [GO:0010467]; modulation of chemical synaptic transmission [GO:0050804]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; regulation of synaptic transmission, glutamatergic [GO:0051966]; sensory perception of pain [GO:0019233] GO:0001640; GO:0001641; GO:0005246; GO:0005886; GO:0007216; GO:0010467; GO:0014069; GO:0019233; GO:0030424; GO:0042734; GO:0043005; GO:0043197; GO:0045211; GO:0050804; GO:0051966; GO:0097110; GO:0097449; GO:0098794; GO:0098978; GO:0099170 11215 XM_029340355.2 303 146 145 290 182 Q08832 1.02e-84 Gamma-aminobutyric acid receptor subunit beta-like (GABA(A) receptor) Drosophila melanogaster (Fruit fly) chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165] GO:0004890; GO:0005231; GO:0005886; GO:0007165; GO:0007268; GO:0022851; GO:0030594; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:1902476; GO:1902711; GO:1904315 11216 XM_029332831.2 1106 732 395 669 589 O43709 9.1e-119 Probable 18S rRNA (guanine-N(7))-methyltransferase (EC 2.1.1.-) (Bud site selection protein 23 homolog) (Metastasis-related methyltransferase 1) (Williams-Beuren syndrome chromosomal region 22 protein) (rRNA methyltransferase and ribosome maturation factor) Homo sapiens (Human) chromatin organization [GO:0006325]; positive regulation of rRNA processing [GO:2000234]; rRNA (guanine-N7)-methylation [GO:0070476] GO:0003723; GO:0005634; GO:0005654; GO:0005730; GO:0006325; GO:0008168; GO:0016435; GO:0046982; GO:0048471; GO:0070476; GO:2000234 11217 XM_029339723.2 187 57 53 169 105 G5EDE1 6.66e-42 Zinc finger protein GFI1 homolog pag-3 (Pattern of reporter gene expression abnormal protein 3) (Transcription factor pag-3) Caenorhabditis elegans negative regulation of apoptotic process [GO:0043066]; negative regulation of insulin secretion [GO:0046676]; negative regulation of neurotransmitter secretion [GO:0046929]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuroblast fate specification [GO:0014018]; regulation of backward locomotion [GO:0043058]; regulation of forward locomotion [GO:0043059]; regulation of neuron differentiation [GO:0045664]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000978; GO:0001222; GO:0001227; GO:0003700; GO:0003714; GO:0005634; GO:0006357; GO:0014018; GO:0030424; GO:0043058; GO:0043059; GO:0043066; GO:0043204; GO:0045664; GO:0046676; GO:0046872; GO:0046929 11218 XM_044326315.1 3756 2628 3670 4164 3346 P62309 2.18e-37 Small nuclear ribonucleoprotein G (snRNP-G) (Sm protein G) (Sm-G) (SmG) Mus musculus (Mouse) mRNA splicing, via spliceosome [GO:0000398]; spliceosomal snRNP assembly [GO:0000387] GO:0000387; GO:0000398; GO:0003723; GO:0005634; GO:0005654; GO:0005681; GO:0005682; GO:0005683; GO:0005685; GO:0005686; GO:0005687; GO:0005689; GO:0005829; GO:0034709; GO:0034719; GO:0043186; GO:0046540; GO:0071004; GO:0071005; GO:0071007; GO:0071011; GO:0071013; GO:0097526; GO:1990446; GO:1990904 11219 XM_044312708.1 6 3 6 0 12 NA NA NA NA NA NA 11220 XM_029344280.2 3091 1824 1685 4260 3224 Q91W43 0 Glycine dehydrogenase (decarboxylating), mitochondrial (EC 1.4.4.2) (Glycine cleavage system P protein) (Glycine decarboxylase) (Glycine dehydrogenase (aminomethyl-transferring)) Mus musculus (Mouse) cellular response to leukemia inhibitory factor [GO:1990830]; glycine catabolic process [GO:0006546]; glycine decarboxylation via glycine cleavage system [GO:0019464]; protein-containing complex assembly [GO:0065003]; response to lipoic acid [GO:1903442]; response to methylamine [GO:0036255] GO:0004375; GO:0005654; GO:0005739; GO:0005886; GO:0005960; GO:0006546; GO:0016594; GO:0016829; GO:0019464; GO:0019899; GO:0030170; GO:0036255; GO:0042803; GO:0065003; GO:0070280; GO:1903442; GO:1990830 11221 XM_044311442.1 5 7 69 530 522 NA NA NA NA NA NA 11222 XM_044323828.1 2644 580 215 1450 1402 Q15434 4.19e-77 RNA-binding motif, single-stranded-interacting protein 2 (Suppressor of CDC2 with RNA-binding motif 3) Homo sapiens (Human) RNA processing [GO:0006396] GO:0003723; GO:0003730; GO:0005634; GO:0005829; GO:0006396; GO:0008143; GO:0008266; GO:1990904 11223 XR_006397475.1 16 0 1 1 14 NA NA NA NA NA NA 11224 XM_029335412.2 74 53 41 83 205 Q92890 9.98e-87 Ubiquitin recognition factor in ER-associated degradation protein 1 (Ubiquitin fusion degradation protein 1) (UB fusion protein 1) Homo sapiens (Human) ER-associated misfolded protein catabolic process [GO:0071712]; negative regulation of RIG-I signaling pathway [GO:0039536]; negative regulation of type I interferon production [GO:0032480]; retrograde protein transport, ER to cytosol [GO:0030970]; skeletal system development [GO:0001501]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0001501; GO:0004843; GO:0005634; GO:0005654; GO:0005829; GO:0006511; GO:0030433; GO:0030970; GO:0031593; GO:0032480; GO:0034098; GO:0036435; GO:0036501; GO:0039536; GO:0071712 11225 XR_006392179.1 1205 276 721 1750 1147 NA NA NA NA NA NA 11226 XM_029349828.2 6138 5222 4003 4587 3497 Q4R6K2 5.7e-48 Proton-coupled zinc antiporter SLC30A1 (Solute carrier family 30 member 1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) defense response to bacterium [GO:0042742]; zinc export across plasma membrane [GO:0140882]; zinc ion import into organelle [GO:0062111] GO:0005886; GO:0016323; GO:0030659; GO:0042742; GO:0046872; GO:0062111; GO:0140826; GO:0140882 11227 XM_029349828.2 6138 5222 4003 4587 3497 Q4R6K2 3.25e-23 Proton-coupled zinc antiporter SLC30A1 (Solute carrier family 30 member 1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) defense response to bacterium [GO:0042742]; zinc export across plasma membrane [GO:0140882]; zinc ion import into organelle [GO:0062111] GO:0005886; GO:0016323; GO:0030659; GO:0042742; GO:0046872; GO:0062111; GO:0140826; GO:0140882 11228 XM_029330714.2 252 453 284 632 732 Q9CQX2 3.92e-34 Cytochrome b5 type B (Cytochrome b5 outer mitochondrial membrane isoform) Mus musculus (Mouse) nitric oxide biosynthetic process [GO:0006809] GO:0005739; GO:0005741; GO:0005743; GO:0006809; GO:0008047; GO:0016020; GO:0020037; GO:0043231; GO:0046872; GO:0050421; GO:1903958 11229 XM_044312007.1 56 43 0 0 46 NA NA NA NA NA NA 11230 XM_029338631.2 1491 1651 1186 2366 1667 NA NA NA NA NA NA 11231 XM_044327140.1 379 240 0 71 20 B3EWZ3 0 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 11232 XM_044327140.1 379 240 0 71 20 B3EWZ3 2.16e-74 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 11233 XM_029341460.2 9 0 7 15 5 Q8IN35 5.3e-36 Neuropeptide SIFamide receptor Drosophila melanogaster (Fruit fly) determination of adult lifespan [GO:0008340]; G protein-coupled receptor signaling pathway [GO:0007186]; mating behavior, sex discrimination [GO:0048047]; neuropeptide signaling pathway [GO:0007218] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0008340; GO:0008528; GO:0016020; GO:0042277; GO:0048047 11234 XM_044322192.1 24 28 10 28 53 NA NA NA NA NA NA 11235 XM_029333223.2 0 1 0 32 0 O75899 1.23e-89 Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51) (HG20) Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway [GO:0007186]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; neuron-glial cell signaling [GO:0150099]; synaptic transmission, GABAergic [GO:0051932] GO:0004888; GO:0004965; GO:0005737; GO:0005886; GO:0007186; GO:0007193; GO:0007194; GO:0007214; GO:0007268; GO:0038039; GO:0043005; GO:0045211; GO:0046982; GO:0051932; GO:0150099; GO:1902710; GO:1902712 11236 XM_029337061.2 321 248 85 175 446 NA NA NA NA NA NA 11237 XM_044314014.1 15 70 8 73 39 NA NA NA NA NA NA 11238 XM_029342327.2 38 199 388 119 66 NA NA NA NA NA NA 11239 XM_044324331.1 689 816 444 766 1142 Q6DRG1 1.38e-56 RNA-binding protein 42 (RNA-binding motif protein 42) Danio rerio (Zebrafish) (Brachydanio rerio) lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003723; GO:0005634; GO:0005737; GO:1990904 11240 XM_029337382.2 4160 5072 1599 4266 2677 Q4PM12 4.92e-31 60S ribosomal protein L36 Ixodes scapularis (Black-legged tick) (Deer tick) translation [GO:0006412] GO:0003735; GO:0005829; GO:0005840; GO:0006412; GO:1990904 11241 XM_029337907.2 994 835 623 986 1113 Q8IUH3 3.24e-92 RNA-binding protein 45 (Developmentally-regulated RNA-binding protein 1) (RB-1) (RNA-binding motif protein 45) Homo sapiens (Human) cell differentiation [GO:0030154]; nervous system development [GO:0007399] GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0007399; GO:0030154; GO:0042802; GO:1990904 11242 XM_029347800.2 112 69 43 107 154 B8VIU6 2.53e-50 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 11243 XM_029353742.2 822 465 536 750 1761 NA NA NA NA NA NA 11244 XM_044324379.1 1625 1118 421 948 909 Q96ME1 2.8e-25 F-box/LRR-repeat protein 18 (F-box and leucine-rich repeat protein 18) Homo sapiens (Human) SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0005829; GO:0019005; GO:0031146 11245 XM_044328803.1 10 10 35 37 7 C3VPR6 1.43e-28 Protein NLRC5 Mus musculus (Mouse) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of type II interferon-mediated signaling pathway [GO:0060335]; regulation of kinase activity [GO:0043549]; response to bacterium [GO:0009617] GO:0000978; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0009617; GO:0032088; GO:0035556; GO:0043549; GO:0045087; GO:0045345; GO:0045944; GO:0051607; GO:0060335; GO:0060339; GO:0060340 11246 XM_029336960.2 318 201 149 280 243 Q8NA66 2.36e-32 Cyclic nucleotide-binding domain-containing protein 1 Homo sapiens (Human) NA NA 11247 XM_044312001.1 0 197 0 0 1 NA NA NA NA NA NA 11248 XM_044319390.1 199 339 332 241 64 NA NA NA NA NA NA 11249 XM_029357209.2 438 272 142 133 73 P00521 1.03e-25 Tyrosine-protein kinase transforming protein Abl (EC 2.7.10.2) (V-abl) Abelson murine leukemia virus NA GO:0004715; GO:0005524 11250 XM_029341313.2 36 28 65 66 46 NA NA NA NA NA NA 11251 XR_006392792.1 7 0 0 0 10 NA NA NA NA NA NA 11252 XM_044316562.1 27 0 31 21 104 NA NA NA NA NA NA 11253 XM_029336160.2 51 1 10 0 21 NA NA NA NA NA NA 11254 XM_029338785.2 449 329 236 550 265 P53461 3.48e-170 Actin, nonmuscle (EC 3.6.4.-) [Cleaved into: Actin, nonmuscle, intermediate form] Halocynthia roretzi (Sea squirt) (Cynthia roretzi) NA GO:0005524; GO:0005737; GO:0005856; GO:0016787 11255 XR_006396985.1 668 285 432 440 1122 NA NA NA NA NA NA 11256 XR_006394001.1 0 0 0 0 9 NA NA NA NA NA NA 11257 XM_044312394.1 188 203 692 380 113 NA NA NA NA NA NA 11258 XM_029342444.2 990 906 244 2705 2086 B9EJV3 6.39e-122 GREB1-like protein Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cardiac ventricle development [GO:0003231]; epithelial tube morphogenesis [GO:0060562]; kidney development [GO:0001822]; male genitalia development [GO:0030539]; mesonephric duct development [GO:0072177]; metanephros development [GO:0001656]; paramesonephric duct development [GO:0061205]; uterus development [GO:0060065] GO:0001656; GO:0001658; GO:0001822; GO:0003231; GO:0016020; GO:0030539; GO:0060065; GO:0060562; GO:0061205; GO:0072177 11259 XM_029342444.2 990 906 244 2705 2086 B9EJV3 7.41e-96 GREB1-like protein Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cardiac ventricle development [GO:0003231]; epithelial tube morphogenesis [GO:0060562]; kidney development [GO:0001822]; male genitalia development [GO:0030539]; mesonephric duct development [GO:0072177]; metanephros development [GO:0001656]; paramesonephric duct development [GO:0061205]; uterus development [GO:0060065] GO:0001656; GO:0001658; GO:0001822; GO:0003231; GO:0016020; GO:0030539; GO:0060065; GO:0060562; GO:0061205; GO:0072177 11260 XM_029342444.2 990 906 244 2705 2086 B9EJV3 8.16e-42 GREB1-like protein Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cardiac ventricle development [GO:0003231]; epithelial tube morphogenesis [GO:0060562]; kidney development [GO:0001822]; male genitalia development [GO:0030539]; mesonephric duct development [GO:0072177]; metanephros development [GO:0001656]; paramesonephric duct development [GO:0061205]; uterus development [GO:0060065] GO:0001656; GO:0001658; GO:0001822; GO:0003231; GO:0016020; GO:0030539; GO:0060065; GO:0060562; GO:0061205; GO:0072177 11261 XM_044318267.1 20 22 26 70 111 NA NA NA NA NA NA 11262 XM_029340751.2 595 755 398 1044 785 Q9QXT8 1.81e-61 Calsenilin (A-type potassium channel modulatory protein 3) (DRE-antagonist modulator) (DREAM) (Kv channel-interacting protein 3) (KChIP3) Mus musculus (Mouse) apoptotic process [GO:0006915]; behavioral response to pain [GO:0048266]; intracellular protein transport [GO:0006886]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; potassium ion transport [GO:0006813]; protein localization to plasma membrane [GO:0072659]; regulation of neuron apoptotic process [GO:0043523]; regulation of potassium ion transmembrane transport [GO:1901379]; response to magnesium ion [GO:0032026]; response to pain [GO:0048265]; sensory perception of pain [GO:0019233] GO:0000122; GO:0000287; GO:0000978; GO:0001046; GO:0001227; GO:0003677; GO:0005244; GO:0005267; GO:0005509; GO:0005634; GO:0005783; GO:0005794; GO:0005829; GO:0006813; GO:0006886; GO:0006915; GO:0008022; GO:0008076; GO:0015459; GO:0019233; GO:0030424; GO:0030425; GO:0032026; GO:0032993; GO:0043167; GO:0043523; GO:0043565; GO:0043679; GO:0044325; GO:0045892; GO:0048265; GO:0048266; GO:0048306; GO:0072659; GO:0140677; GO:1901379 11263 XR_006395344.1 5 9 0 0 0 NA NA NA NA NA NA 11264 XR_003825281.2 35 39 47 65 115 NA NA NA NA NA NA 11265 XM_029333436.2 1197 0 318 1510 0 P55115 9.64e-48 Zinc metalloproteinase nas-15 (EC 3.4.24.-) (Nematode astacin 15) Caenorhabditis elegans proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0006508; GO:0008270 11266 XM_029358709.2 15 1 0 6 0 NA NA NA NA NA NA 11267 XM_029332674.2 356 198 263 303 459 F1Q8J0 3.43e-45 RNA-binding region-containing protein 3 (RNA-binding protein 40) Danio rerio (Zebrafish) (Brachydanio rerio) digestive tract development [GO:0048565]; liver development [GO:0001889]; mRNA splicing, via spliceosome [GO:0000398]; pancreas development [GO:0031016] GO:0000398; GO:0001889; GO:0005689; GO:0030626; GO:0031016; GO:0048565; GO:0097157 11268 XM_029339630.2 794 715 414 614 342 Q8IUR5 0 Protein O-mannosyl-transferase TMTC1 (EC 2.4.1.109) (Transmembrane and TPR repeat-containing protein 1) Homo sapiens (Human) protein O-linked mannosylation [GO:0035269]; RNA processing [GO:0006396] GO:0000030; GO:0004169; GO:0005783; GO:0006396; GO:0016020; GO:0035269 11269 XM_044318224.1 590 479 153 520 237 Q8C1D8 1.17e-85 Protein IWS1 homolog (IWS1-like protein) Mus musculus (Mouse) mRNA processing [GO:0006397]; poly(A)+ mRNA export from nucleus [GO:0016973]; regulation of histone H3-K36 trimethylation [GO:2001253]; regulation of histone H4 acetylation [GO:0090239]; regulation of mRNA export from nucleus [GO:0010793]; regulation of mRNA processing [GO:0050684]; RNA splicing [GO:0008380] GO:0005634; GO:0005654; GO:0006397; GO:0008380; GO:0010793; GO:0016973; GO:0050684; GO:0090239; GO:2001253 11270 XM_029356442.2 0 44 48 0 123 P07584 2.33e-29 Astacin (EC 3.4.24.21) (Crayfish small molecule proteinase) Astacus astacus (Noble crayfish) (Astacus fluviatilis) cell adhesion [GO:0007155]; fertilization [GO:0009566]; negative regulation of binding of sperm to zona pellucida [GO:2000360]; positive regulation of protein processing [GO:0010954]; prevention of polyspermy [GO:0060468]; proteolysis [GO:0006508] GO:0004222; GO:0005737; GO:0005886; GO:0006508; GO:0007155; GO:0008233; GO:0008270; GO:0009566; GO:0010954; GO:0060468; GO:0060473; GO:0070001; GO:0070002; GO:2000360 11271 XM_044326669.1 1116 457 814 5163 7188 Q68FL4 0 Putative adenosylhomocysteinase 3 (AdoHcyase 3) (EC 3.13.2.1) (Long-IRBIT) (S-adenosyl-L-homocysteine hydrolase 3) (S-adenosylhomocysteine hydrolase-like protein 2) Mus musculus (Mouse) one-carbon metabolic process [GO:0006730]; S-adenosylmethionine cycle [GO:0033353] GO:0005783; GO:0005829; GO:0006730; GO:0016787; GO:0033353; GO:0043005; GO:0043231 11272 XM_029355121.2 0 0 7 8 65 NA NA NA NA NA NA 11273 XM_029323922.2 3 0 0 7 0 E7FAM5 2.12e-77 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 11274 XM_044323572.1 170 37 58 32 183 NA NA NA NA NA NA 11275 XM_029324758.2 189 0 0 50 147 Q9H0Z9 1.58e-31 RNA-binding protein 38 (CLL-associated antigen KW-5) (HSRNASEB) (RNA-binding motif protein 38) (RNA-binding region-containing protein 1) (ssDNA-binding protein SEB4) Homo sapiens (Human) 3'-UTR-mediated mRNA stabilization [GO:0070935]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; mRNA processing [GO:0006397]; mRNA stabilization [GO:0048255]; negative regulation of cell population proliferation [GO:0008285]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of cell cycle [GO:0051726]; regulation of myotube differentiation [GO:0010830]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380] GO:0000381; GO:0003723; GO:0003729; GO:0003730; GO:0005634; GO:0005829; GO:0006397; GO:0006977; GO:0006978; GO:0007049; GO:0008285; GO:0008380; GO:0010830; GO:0030154; GO:0043484; GO:0048255; GO:0051726; GO:0070935 11276 XM_029330530.2 778 285 505 342 509 Q863A0 8.26e-40 Complement C2 (EC 3.4.21.43) (C3/C5 convertase) [Cleaved into: Complement C2b fragment; Complement C2a fragment] Gorilla gorilla gorilla (Western lowland gorilla) complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; proteolysis [GO:0006508]; response to bacterium [GO:0009617] GO:0004252; GO:0005601; GO:0006508; GO:0006956; GO:0006958; GO:0009617; GO:0045087; GO:0046872 11277 XM_029353191.2 567 258 257 566 322 Q6NTR1 4.22e-149 eEF1A lysine and N-terminal methyltransferase (Methyltransferase-like protein 13) [Includes: eEF1A lysine methyltransferase (EC 2.1.1.-); eEF1A N-terminal methyltransferase (EC 2.1.1.-)] Xenopus laevis (African clawed frog) NA GO:0016279 11278 XM_029335231.2 492 273 464 322 856 Q8BGT5 5.01e-148 Alanine aminotransferase 2 (ALT2) (EC 2.6.1.2) (Glutamate pyruvate transaminase 2) (GPT 2) (Glutamic--alanine transaminase 2) (Glutamic--pyruvic transaminase 2) Mus musculus (Mouse) 2-oxoglutarate metabolic process [GO:0006103]; biosynthetic process [GO:0009058]; L-alanine catabolic process [GO:0042853]; L-alanine metabolic process [GO:0042851]; positive regulation of gluconeogenesis [GO:0045722] GO:0004021; GO:0005615; GO:0005739; GO:0006103; GO:0009058; GO:0030170; GO:0042851; GO:0042853; GO:0045722 11279 XM_029358462.2 29 0 0 0 27 P54131 1.8e-65 Neuronal acetylcholine receptor subunit alpha-7 Bos taurus (Bovine) calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; cognition [GO:0050890]; ion transmembrane transport [GO:0034220]; negative regulation of tumor necrosis factor production [GO:0032720]; nervous system process [GO:0050877]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAPK cascade [GO:0043410]; regulation of membrane potential [GO:0042391]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271] GO:0001540; GO:0001666; GO:0005231; GO:0005886; GO:0005892; GO:0006816; GO:0006874; GO:0007165; GO:0007268; GO:0007271; GO:0008284; GO:0015464; GO:0015643; GO:0017081; GO:0022848; GO:0030594; GO:0032720; GO:0034220; GO:0035094; GO:0042166; GO:0042391; GO:0042803; GO:0043005; GO:0043410; GO:0045202; GO:0045211; GO:0045766; GO:0050877; GO:0050890; GO:1904315 11280 XM_029348390.2 744 712 450 743 551 A4XU32 1.21e-58 Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase (HMG aldolase) (EC 4.1.3.17) (Oxaloacetate decarboxylase) (OAA decarboxylase) (EC 4.1.1.112) (Regulator of ribonuclease activity homolog) (RraA-like protein) Pseudomonas mendocina (strain ymp) regulation of RNA metabolic process [GO:0051252] GO:0008428; GO:0008948; GO:0046872; GO:0047443; GO:0051252 11281 XM_044316087.1 0 2 5 0 7 NA NA NA NA NA NA 11282 XM_044308057.1 290 608 862 469 356 P25439 0 ATP-dependent helicase brm (EC 3.6.4.12) (Homeotic gene regulator) (Protein brahma) Drosophila melanogaster (Fruit fly) axonogenesis [GO:0007409]; cell dedifferentiation [GO:0043697]; chromatin remodeling [GO:0006338]; dendrite guidance [GO:0070983]; dendrite morphogenesis [GO:0048813]; hemocyte proliferation [GO:0035172]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of neuroblast proliferation [GO:0007406]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of innate immune response [GO:0045088]; regulation of neuroblast proliferation [GO:1902692]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription initiation-coupled chromatin remodeling [GO:0045815]; ventral cord development [GO:0007419] GO:0001223; GO:0003677; GO:0004386; GO:0005524; GO:0005634; GO:0005700; GO:0006338; GO:0006357; GO:0007406; GO:0007409; GO:0007419; GO:0007474; GO:0008094; GO:0008586; GO:0008587; GO:0016887; GO:0035060; GO:0035172; GO:0036335; GO:0042393; GO:0043697; GO:0045088; GO:0045815; GO:0045893; GO:0045944; GO:0048813; GO:0070983; GO:0140297; GO:0140566; GO:0140658; GO:1902692; GO:2000134; GO:2000648 11283 XM_029350828.2 1043 1176 635 1057 980 P38024 6.4e-180 Multifunctional protein ADE2 [Includes: Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6) (SAICAR synthetase); Phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) (AIR carboxylase) (AIRC)] Gallus gallus (Chicken) 'de novo' IMP biosynthetic process [GO:0006189] GO:0004638; GO:0004639; GO:0005524; GO:0005829; GO:0006189; GO:0043727 11284 XR_003825176.2 52 27 27 84 15 NA NA NA NA NA NA 11285 XM_044314958.1 92 68 120 81 167 B8UU78 9.32e-118 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 11286 XM_044322225.1 2 29 14 87 80 NA NA NA NA NA NA 11287 XM_044313234.1 0 7 0 0 0 NA NA NA NA NA NA 11288 XM_044324706.1 4 8 4 11 34 NA NA NA NA NA NA 11289 XR_006391487.1 34 6 27 70 26 NA NA NA NA NA NA 11290 XM_029356291.2 12 1 53 0 57 NA NA NA NA NA NA 11291 XM_029338565.2 679 512 330 860 940 Q96EY7 5.34e-41 Pentatricopeptide repeat domain-containing protein 3, mitochondrial (28S ribosomal protein S39, mitochondrial) (MRP-S39) (Mitochondrial small ribosomal subunit protein mS39) (Transformation-related gene 15 protein) (TRG-15) Homo sapiens (Human) mitochondrial translation [GO:0032543]; regulation of translation [GO:0006417] GO:0003723; GO:0005654; GO:0005739; GO:0005743; GO:0005763; GO:0005829; GO:0005886; GO:0006417; GO:0019843; GO:0032543; GO:0043024 11292 XM_029347042.2 5858 3799 4602 6927 5733 Q92005 0 Elongation factor 1-alpha (EF-1-alpha) Danio rerio (Zebrafish) (Brachydanio rerio) translation [GO:0006412]; translational elongation [GO:0006414] GO:0003746; GO:0003924; GO:0005525; GO:0005737; GO:0006412; GO:0006414 11293 XR_006392575.1 26 12 29 36 32 NA NA NA NA NA NA 11294 XM_029343453.2 85 50 69 0 0 NA NA NA NA NA NA 11295 XM_044327767.1 4206 5266 1833 2052 1508 Q7Z7E8 3.22e-72 Ubiquitin-conjugating enzyme E2 Q1 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme Q1) (Protein NICE-5) (Ubiquitin carrier protein Q1) (Ubiquitin-protein ligase Q1) Homo sapiens (Human) embryo implantation [GO:0007566]; fertilization [GO:0009566]; mating behavior [GO:0007617]; prolactin secretion [GO:0070459]; protein polyubiquitination [GO:0000209]; reproductive system development [GO:0061458]; suckling behavior [GO:0001967] GO:0000209; GO:0001967; GO:0005524; GO:0005634; GO:0005829; GO:0007566; GO:0007617; GO:0009566; GO:0030175; GO:0061458; GO:0061631; GO:0070459 11296 XM_044316431.1 1 2 0 19 28 NA NA NA NA NA NA 11297 XM_029337046.2 1695 1058 1224 1638 1926 Q9C0G6 0 Dynein axonemal heavy chain 6 (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0045505; GO:0051959 11298 XM_044318120.1 121 54 100 113 96 NA NA NA NA NA NA 11299 XM_029339562.2 61 0 0 0 0 Q17RD7 4.96e-71 Synaptotagmin-16 (Chr14Syt) (Synaptotagmin 14-like protein) (Synaptotagmin XIV-related protein) Homo sapiens (Human) NA GO:0005543; GO:0042802 11300 XM_044327675.1 17 0 0 0 0 NA NA NA NA NA NA 11301 XM_044328607.1 309 312 172 293 387 Q5NVA9 1.04e-50 Crossover junction endonuclease EME1 (EC 3.1.22.-) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) DNA recombination [GO:0006310]; DNA repair [GO:0006281] GO:0003677; GO:0004519; GO:0005730; GO:0006281; GO:0006310; GO:0043596; GO:0046872; GO:0048476 11302 XM_029335646.2 35 154 55 60 83 Q8N8A2 3.48e-77 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (PP6-ARS-B) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-B) (Ankyrin repeat domain-containing protein 44) Homo sapiens (Human) NA NA 11303 XM_029335646.2 35 154 55 60 83 Q8N8A2 4.02e-70 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (PP6-ARS-B) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-B) (Ankyrin repeat domain-containing protein 44) Homo sapiens (Human) NA NA 11304 XM_029335646.2 35 154 55 60 83 Q8N8A2 1.19e-65 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (PP6-ARS-B) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-B) (Ankyrin repeat domain-containing protein 44) Homo sapiens (Human) NA NA 11305 XM_029335646.2 35 154 55 60 83 Q8N8A2 6.52e-42 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (PP6-ARS-B) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-B) (Ankyrin repeat domain-containing protein 44) Homo sapiens (Human) NA NA 11306 XM_044311170.1 111 31 0 284 493 NA NA NA NA NA NA 11307 XM_044320741.1 4 1 9 22 70 D3YXG0 1.03e-22 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 11308 XM_044320741.1 4 1 9 22 70 D3YXG0 1.38e-21 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 11309 XM_044310547.1 0 6 8 4 28 NA NA NA NA NA NA 11310 XM_044310902.1 0 6 0 7 0 NA NA NA NA NA NA 11311 XM_029327682.2 0 3 0 28 20 NA NA NA NA NA NA 11312 XM_029324911.2 424 1078 331 782 394 Q3UFF7 1.78e-34 Lysophospholipase-like protein 1 (EC 3.1.2.22) Mus musculus (Mouse) negative regulation of Golgi to plasma membrane protein transport [GO:0042997]; protein depalmitoylation [GO:0002084] GO:0002084; GO:0005737; GO:0005829; GO:0008474; GO:0042997 11313 XM_029327420.2 1145 377 188 321 281 Q9D7I5 4.56e-99 Phospholysine phosphohistidine inorganic pyrophosphate phosphatase (EC 3.1.3.-) (EC 3.6.1.1) Mus musculus (Mouse) dephosphorylation [GO:0016311]; phosphate-containing compound metabolic process [GO:0006796] GO:0004427; GO:0005634; GO:0005829; GO:0006796; GO:0016311; GO:0016607; GO:0016791; GO:0042803; GO:0046872 11314 XM_044323194.1 9 0 28 0 60 O73792 7.91e-53 Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1) Danio rerio (Zebrafish) (Brachydanio rerio) angiogenesis [GO:0001525]; blood vessel development [GO:0001568]; endothelial cell-cell adhesion [GO:0071603]; heart development [GO:0007507]; positive regulation of angiogenesis [GO:0045766]; positive regulation of kinase activity [GO:0033674]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculature development [GO:0001944] GO:0001525; GO:0001568; GO:0001944; GO:0004714; GO:0005524; GO:0005886; GO:0007169; GO:0007507; GO:0033674; GO:0043235; GO:0045766; GO:0071603 11315 XM_044321191.1 35 36 6 64 24 NA NA NA NA NA NA 11316 XM_029343983.2 52 22 83 29 118 Q96IK5 1.68e-105 Germ cell-less protein-like 1 (Spermatogenesis-associated protein 29) Homo sapiens (Human) germ cell development [GO:0007281]; spermatogenesis [GO:0007283] GO:0005634; GO:0007281; GO:0007283; GO:0016363; GO:0042802 11317 XR_006395906.1 208 48 283 72 978 NA NA NA NA NA NA 11318 XM_029353783.2 52 0 19 14 11 Q5PPZ5 7.36e-47 Bridging integrator 3 homolog Xenopus laevis (African clawed frog) actin cortical patch localization [GO:0051666]; division septum assembly [GO:0000917]; endocytosis [GO:0006897] GO:0000917; GO:0005737; GO:0005856; GO:0006897; GO:0051666 11319 XM_029335351.2 989 0 446 1191 831 D3Z902 3.85e-49 F-box/WD repeat-containing protein 7 Rattus norvegicus (Rat) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; lung development [GO:0030324]; negative regulation of gene expression [GO:0010629]; negative regulation of osteoclast development [GO:2001205]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; Notch signaling pathway [GO:0007219]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903378]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein destabilization [GO:0031648]; protein K63-linked ubiquitination [GO:0070534]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of cell migration involved in sprouting angiogenesis [GO:0090049]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; sister chromatid cohesion [GO:0007062]; ubiquitin recycling [GO:0010992]; vasculogenesis [GO:0001570] GO:0001570; GO:0005634; GO:0005694; GO:0005730; GO:0005737; GO:0005739; GO:0005783; GO:0005794; GO:0006281; GO:0006974; GO:0007062; GO:0007219; GO:0010629; GO:0010992; GO:0016567; GO:0019005; GO:0030324; GO:0030332; GO:0030674; GO:0031146; GO:0031398; GO:0031625; GO:0031648; GO:0042752; GO:0042802; GO:0043130; GO:0043161; GO:0045741; GO:0048471; GO:0048511; GO:0050816; GO:0050821; GO:0051443; GO:0070374; GO:0070534; GO:0090049; GO:0097027; GO:1901800; GO:1903026; GO:1903146; GO:1903378; GO:1903955; GO:1990452; GO:1990756; GO:2000060; GO:2001205 11320 XM_029335351.2 989 0 446 1191 831 D3Z902 1.29e-42 F-box/WD repeat-containing protein 7 Rattus norvegicus (Rat) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; lung development [GO:0030324]; negative regulation of gene expression [GO:0010629]; negative regulation of osteoclast development [GO:2001205]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; Notch signaling pathway [GO:0007219]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903378]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein destabilization [GO:0031648]; protein K63-linked ubiquitination [GO:0070534]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of cell migration involved in sprouting angiogenesis [GO:0090049]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; sister chromatid cohesion [GO:0007062]; ubiquitin recycling [GO:0010992]; vasculogenesis [GO:0001570] GO:0001570; GO:0005634; GO:0005694; GO:0005730; GO:0005737; GO:0005739; GO:0005783; GO:0005794; GO:0006281; GO:0006974; GO:0007062; GO:0007219; GO:0010629; GO:0010992; GO:0016567; GO:0019005; GO:0030324; GO:0030332; GO:0030674; GO:0031146; GO:0031398; GO:0031625; GO:0031648; GO:0042752; GO:0042802; GO:0043130; GO:0043161; GO:0045741; GO:0048471; GO:0048511; GO:0050816; GO:0050821; GO:0051443; GO:0070374; GO:0070534; GO:0090049; GO:0097027; GO:1901800; GO:1903026; GO:1903146; GO:1903378; GO:1903955; GO:1990452; GO:1990756; GO:2000060; GO:2001205 11321 XM_029335351.2 989 0 446 1191 831 D3Z902 1.58e-41 F-box/WD repeat-containing protein 7 Rattus norvegicus (Rat) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; lung development [GO:0030324]; negative regulation of gene expression [GO:0010629]; negative regulation of osteoclast development [GO:2001205]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; Notch signaling pathway [GO:0007219]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903378]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein destabilization [GO:0031648]; protein K63-linked ubiquitination [GO:0070534]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of cell migration involved in sprouting angiogenesis [GO:0090049]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; sister chromatid cohesion [GO:0007062]; ubiquitin recycling [GO:0010992]; vasculogenesis [GO:0001570] GO:0001570; GO:0005634; GO:0005694; GO:0005730; GO:0005737; GO:0005739; GO:0005783; GO:0005794; GO:0006281; GO:0006974; GO:0007062; GO:0007219; GO:0010629; GO:0010992; GO:0016567; GO:0019005; GO:0030324; GO:0030332; GO:0030674; GO:0031146; GO:0031398; GO:0031625; GO:0031648; GO:0042752; GO:0042802; GO:0043130; GO:0043161; GO:0045741; GO:0048471; GO:0048511; GO:0050816; GO:0050821; GO:0051443; GO:0070374; GO:0070534; GO:0090049; GO:0097027; GO:1901800; GO:1903026; GO:1903146; GO:1903378; GO:1903955; GO:1990452; GO:1990756; GO:2000060; GO:2001205 11322 XR_006393996.1 2838 1764 1357 4189 2501 P70191 1.96e-22 TNF receptor-associated factor 5 Mus musculus (Mouse) apoptotic process [GO:0006915]; interleukin-17-mediated signaling pathway [GO:0097400]; mRNA stabilization [GO:0048255]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of JNK cascade [GO:0046330]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; signal transduction [GO:0007165]; signal transduction involved in regulation of gene expression [GO:0023019]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0005164; GO:0005813; GO:0005829; GO:0006915; GO:0007165; GO:0008270; GO:0008284; GO:0009898; GO:0023019; GO:0031625; GO:0031996; GO:0033209; GO:0035631; GO:0042802; GO:0042981; GO:0043122; GO:0043123; GO:0046330; GO:0048255; GO:0051091; GO:0051092; GO:0070534; GO:0097400 11323 XM_029353263.2 12 0 0 14 0 NA NA NA NA NA NA 11324 XM_044311877.1 13 0 33 15 20 NA NA NA NA NA NA 11325 XM_029348149.2 2642 1814 1355 2455 2417 Q7ZU42 0 Obg-like ATPase 1 Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005524; GO:0005525; GO:0005730; GO:0005737; GO:0016887; GO:0043022; GO:0043023; GO:0046872 11326 XM_044312829.1 111 67 62 109 134 Q5R7P4 0 Beta-galactosidase (EC 3.2.1.23) (Acid beta-galactosidase) (Lactase) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) carbohydrate metabolic process [GO:0005975] GO:0004565; GO:0005764; GO:0005975 11327 XM_044321483.1 1871 2766 815 1339 600 NA NA NA NA NA NA 11328 XM_044307813.1 14 6 15 5 0 NA NA NA NA NA NA 11329 XM_029344260.2 138 57 76 58 177 NA NA NA NA NA NA 11330 XM_044311905.1 114 80 17 55 12 NA NA NA NA NA NA 11331 XR_006392604.1 49 0 3 0 31 NA NA NA NA NA NA 11332 XM_044313031.1 10 14 8 0 0 NA NA NA NA NA NA 11333 XM_044311157.1 13 5 21 11 18 NA NA NA NA NA NA 11334 XM_029344290.2 532 676 406 435 833 A7SN31 1.81e-136 S-methyl-5'-thioadenosine phosphorylase (EC 2.4.2.28) (5'-methylthioadenosine phosphorylase) (MTA phosphorylase) (MTAP) (MTAPase) Nematostella vectensis (Starlet sea anemone) L-methionine salvage from methylthioadenosine [GO:0019509]; purine ribonucleoside salvage [GO:0006166] GO:0005634; GO:0005829; GO:0006166; GO:0017061; GO:0019509 11335 XM_029343227.2 1087 2524 1635 1410 643 O35972 8.29e-32 39S ribosomal protein L23, mitochondrial (L23mt) (MRP-L23) (L23 mitochondrial-related protein) Mus musculus (Mouse) mitochondrial translation [GO:0032543]; translation [GO:0006412] GO:0001650; GO:0003735; GO:0005739; GO:0005743; GO:0005762; GO:0006412; GO:0032543 11336 XM_029340184.2 936 923 564 801 773 Q9BRF8 4.08e-92 Serine/threonine-protein phosphatase CPPED1 (EC 3.1.3.16) (Calcineurin-like phosphoesterase domain-containing protein 1) (Complete S-transactivated protein 1) Homo sapiens (Human) NA GO:0005576; GO:0005829; GO:0005886; GO:0017018; GO:0035578; GO:0046872 11337 XM_044312847.1 612 612 318 490 356 Q5RB83 2.1e-88 Phosphoserine phosphatase (PSP) (PSPase) (EC 3.1.3.3) (O-phosphoserine phosphohydrolase) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) L-serine biosynthetic process [GO:0006564]; L-serine metabolic process [GO:0006563] GO:0000287; GO:0005829; GO:0006563; GO:0006564; GO:0036424 11338 XM_044327870.1 1 0 9 5 11 NA NA NA NA NA NA 11339 XR_006391302.1 86 144 127 129 181 NA NA NA NA NA NA 11340 XM_029333894.2 31 62 17 14 49 NA NA NA NA NA NA 11341 XR_006392460.1 59 20 25 35 71 NA NA NA NA NA NA 11342 XM_044317387.1 0 0 37 0 0 NA NA NA NA NA NA 11343 XM_029351115.2 2 43 30 0 25 NA NA NA NA NA NA 11344 XM_044316309.1 33 0 0 0 2 NA NA NA NA NA NA 11345 XM_029346148.2 0 48 68 35 168 NA NA NA NA NA NA 11346 XM_044317326.1 716 280 333 282 1141 Q86AW9 7.8e-144 Guanine deaminase (Guanase) (Guanine aminase) (EC 3.5.4.3) (Guanine aminohydrolase) (GAH) Dictyostelium discoideum (Social amoeba) guanine catabolic process [GO:0006147]; guanine metabolic process [GO:0046098] GO:0005829; GO:0006147; GO:0008270; GO:0008892; GO:0019239; GO:0046098 11347 XR_006397663.1 45 11 10 38 73 NA NA NA NA NA NA 11348 XM_044321501.1 0 0 8 3 7 NA NA NA NA NA NA 11349 XR_006398173.1 466 339 380 623 616 F8W2M1 3.22e-38 E3 ubiquitin-protein ligase HACE1 (EC 2.3.2.26) (HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1) (HECT-type E3 ubiquitin transferase HACE1) Danio rerio (Zebrafish) (Brachydanio rerio) atrioventricular valve formation [GO:0003190]; cardiac ventricle morphogenesis [GO:0003208]; cell cycle [GO:0007049]; Golgi organization [GO:0007030]; heart looping [GO:0001947]; membrane fusion [GO:0061025]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of cell migration [GO:0030334]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000139; GO:0000209; GO:0001947; GO:0003190; GO:0003208; GO:0004842; GO:0005634; GO:0005737; GO:0005783; GO:0006511; GO:0007030; GO:0007049; GO:0016567; GO:0030334; GO:0031267; GO:0032580; GO:0043161; GO:0061025; GO:0061630; GO:0070936; GO:1903427 11350 XR_006398173.1 466 339 380 623 616 F8W2M1 3.22e-38 E3 ubiquitin-protein ligase HACE1 (EC 2.3.2.26) (HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1) (HECT-type E3 ubiquitin transferase HACE1) Danio rerio (Zebrafish) (Brachydanio rerio) atrioventricular valve formation [GO:0003190]; cardiac ventricle morphogenesis [GO:0003208]; cell cycle [GO:0007049]; Golgi organization [GO:0007030]; heart looping [GO:0001947]; membrane fusion [GO:0061025]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of cell migration [GO:0030334]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000139; GO:0000209; GO:0001947; GO:0003190; GO:0003208; GO:0004842; GO:0005634; GO:0005737; GO:0005783; GO:0006511; GO:0007030; GO:0007049; GO:0016567; GO:0030334; GO:0031267; GO:0032580; GO:0043161; GO:0061025; GO:0061630; GO:0070936; GO:1903427 11351 XM_044319785.1 0 71 13 562 0 Q9P2E3 0 NFX1-type zinc finger-containing protein 1 Homo sapiens (Human) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 11352 XM_044319785.1 0 71 13 562 0 Q9P2E3 3.02e-67 NFX1-type zinc finger-containing protein 1 Homo sapiens (Human) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 11353 XM_044316591.1 851 511 408 642 889 Q6PDG8 3.96e-157 Vacuolar fusion protein MON1 homolog A Mus musculus (Mouse) cellular iron ion homeostasis [GO:0006879]; establishment of localization in cell [GO:0051649]; protein secretion [GO:0009306]; protein targeting to vacuole [GO:0006623]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] GO:0005085; GO:0006623; GO:0006879; GO:0009306; GO:0015031; GO:0016192; GO:0035658; GO:0051649 11354 XR_003823533.2 0 0 0 1 8 NA NA NA NA NA NA 11355 XM_044326544.1 46 15 18 62 38 NA NA NA NA NA NA 11356 XM_044322055.1 0 5 18 0 0 Q5W041 6.27e-161 Armadillo repeat-containing protein 3 (Beta-catenin-like protein) (Cancer/testis antigen 81) (CT81) (KU-CT-1) Homo sapiens (Human) NA GO:0070062 11357 XM_044322055.1 0 5 18 0 0 Q5W041 5.52e-43 Armadillo repeat-containing protein 3 (Beta-catenin-like protein) (Cancer/testis antigen 81) (CT81) (KU-CT-1) Homo sapiens (Human) NA GO:0070062 11358 XM_029355864.2 16 47 6 45 14 P13608 3.23e-22 Aggrecan core protein (Cartilage-specific proteoglycan core protein) (CSPCP) Bos taurus (Bovine) cell adhesion [GO:0007155]; central nervous system development [GO:0007417]; skeletal system development [GO:0001501] GO:0001501; GO:0005509; GO:0005540; GO:0005576; GO:0007155; GO:0007417; GO:0030246; GO:0031012 11359 XR_006394846.1 11 0 8 7 9 NA NA NA NA NA NA 11360 XM_044315518.1 48 49 28 27 23 Q96AY4 7.47e-128 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11361 XM_044315518.1 48 49 28 27 23 Q96AY4 5.33e-123 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11362 XM_044315518.1 48 49 28 27 23 Q96AY4 1.08e-114 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11363 XM_044315518.1 48 49 28 27 23 Q96AY4 5.42e-93 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11364 XM_044315518.1 48 49 28 27 23 Q96AY4 2.05e-71 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11365 XM_044315518.1 48 49 28 27 23 Q96AY4 2.35e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11366 XM_044327474.1 1 3 26 24 1 NA NA NA NA NA NA 11367 XM_029341435.2 1220 976 1357 1022 675 NA NA NA NA NA NA 11368 XM_044322058.1 0 290 244 337 0 Q7RTR2 5.57e-66 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11369 XM_044322058.1 0 290 244 337 0 Q7RTR2 7.73e-65 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11370 XM_044322058.1 0 290 244 337 0 Q7RTR2 9.35e-41 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11371 XM_044322806.1 0 0 240 110 18 Q13591 1.5e-71 Semaphorin-5A (Semaphorin-F) (Sema F) Homo sapiens (Human) axon extension [GO:0048675]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell-cell signaling [GO:0007267]; diencephalon development [GO:0021536]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of cell adhesion [GO:0007162]; negative regulation of endothelial cell apoptotic process [GO:2000352]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; positive chemotaxis [GO:0050918]; positive regulation of actin filament depolymerization [GO:0030836]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein kinase B signaling [GO:0051897]; semaphorin-plexin signaling pathway [GO:0071526]; signal clustering [GO:1990256] GO:0001755; GO:0001938; GO:0002043; GO:0005886; GO:0007155; GO:0007162; GO:0007267; GO:0007399; GO:0007411; GO:0007413; GO:0016020; GO:0021536; GO:0030215; GO:0030335; GO:0030836; GO:0035373; GO:0043395; GO:0045499; GO:0045545; GO:0045766; GO:0048675; GO:0048842; GO:0048843; GO:0050918; GO:0051897; GO:0060326; GO:0070062; GO:0071526; GO:0090263; GO:1990256; GO:2000352; GO:2001028 11372 XM_029348114.2 390 458 122 282 319 Q9CXI3 2.46e-121 DBH-like monooxygenase protein 1 (EC 1.14.17.-) (DBH-related protein) (Monooxygenase X) Mus musculus (Mouse) dopamine catabolic process [GO:0042420]; norepinephrine biosynthetic process [GO:0042421]; octopamine biosynthetic process [GO:0006589] GO:0004500; GO:0005507; GO:0005615; GO:0005789; GO:0006589; GO:0030667; GO:0042420; GO:0042421 11373 XM_044312072.1 121 276 64 77 344 R1CW23 1.75e-109 Dimethylsulfonioproprionate lyase 7 (DMSP lyase 7) (EC 4.4.1.3) (Dimethylpropiothetin dethiomethylase 7) Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi) NA GO:0047869 11374 XM_029335393.2 714 556 432 733 672 Q04678 0 FACT complex subunit SSRP1 (Facilitates chromatin transcription complex subunit SSRP1) (Recombination signal sequence recognition protein 1) (Structure-specific recognition protein 1) (T160) Gallus gallus (Chicken) cellular component organization [GO:0016043]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; regulation of chromatin organization [GO:1902275] GO:0003677; GO:0005730; GO:0006260; GO:0006281; GO:0016043; GO:0031491; GO:0035101; GO:0042393; GO:1902275 11375 XM_044324282.1 1786 427 1832 1391 497 Q3SYW2 1.44e-62 Complement C2 (EC 3.4.21.43) (C3/C5 convertase) [Cleaved into: Complement C2b fragment; Complement C2a fragment] Bos taurus (Bovine) complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; proteolysis [GO:0006508]; response to bacterium [GO:0009617] GO:0004252; GO:0005601; GO:0006508; GO:0006956; GO:0006958; GO:0009617; GO:0045087; GO:0046872 11376 XM_044318194.1 244 150 249 164 829 B4E2M5 1.25e-25 Ankyrin repeat domain-containing protein 66 Homo sapiens (Human) NA NA 11377 XM_044323492.1 85 116 170 165 85 Q96AY4 3.91e-115 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11378 XM_044323492.1 85 116 170 165 85 Q96AY4 2.13e-112 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11379 XM_044323492.1 85 116 170 165 85 Q96AY4 9.8e-97 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11380 XM_044323492.1 85 116 170 165 85 Q96AY4 2.32e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11381 XM_044323492.1 85 116 170 165 85 Q96AY4 3.59e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11382 XM_029337500.2 604 391 347 792 1000 NA NA NA NA NA NA 11383 XM_029346603.2 119 217 17 96 72 NA NA NA NA NA NA 11384 XM_029348586.2 728 711 502 673 729 P59722 7.87e-71 Egl nine homolog 1 (EC 1.14.11.29) (Hypoxia-inducible factor prolyl hydroxylase 2) (HIF-PH2) (HIF-prolyl hydroxylase 2) (HPH-2) (Prolyl hydroxylase domain-containing protein 2) (PHD2) Rattus norvegicus (Rat) cardiac muscle tissue morphogenesis [GO:0055008]; cellular iron ion homeostasis [GO:0006879]; cellular oxygen homeostasis [GO:0032364]; cellular response to hypoxia [GO:0071456]; heart trabecula formation [GO:0060347]; labyrinthine layer development [GO:0060711]; negative regulation of CAMKK-AMPK signaling cascade [GO:1905290]; negative regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051344]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; positive regulation of apoptotic process [GO:0043065]; positive regulation of neuron death [GO:1901216]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of angiogenesis [GO:0045765]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of neuron death [GO:1901214]; regulation of postsynapse organization [GO:0099175]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation protein catabolic process at postsynapse [GO:0140252]; response to hypoxia [GO:0001666]; response to nitric oxide [GO:0071731]; ventricular septum morphogenesis [GO:0060412] GO:0001666; GO:0005634; GO:0005737; GO:0005829; GO:0006879; GO:0008198; GO:0014069; GO:0016706; GO:0018401; GO:0019899; GO:0031418; GO:0031543; GO:0031545; GO:0032364; GO:0043065; GO:0043433; GO:0045765; GO:0045944; GO:0051344; GO:0055008; GO:0060347; GO:0060412; GO:0060711; GO:0071456; GO:0071731; GO:0098978; GO:0099159; GO:0099175; GO:0099576; GO:0140252; GO:1901214; GO:1901216; GO:1905290 11385 XM_029344749.2 4234 3993 2445 3254 3109 Q0P5Y3 1.08e-34 Tubulin polymerization-promoting protein family member 2 Mus musculus (Mouse) cell differentiation [GO:0030154]; microtubule polymerization [GO:0046785]; positive regulation of protein polymerization [GO:0032273]; regulation of flagellated sperm motility [GO:1901317]; spermatogenesis [GO:0007283] GO:0005829; GO:0007283; GO:0015631; GO:0030154; GO:0032273; GO:0036126; GO:0046785; GO:1901317 11386 XM_029334760.2 5 0 0 62 71 NA NA NA NA NA NA 11387 XM_044322414.1 17 0 0 19 22 NA NA NA NA NA NA 11388 XM_029346230.2 13 0 8 4 40 Q9WTK8 1.19e-131 Meiotic recombination protein SPO11 (EC 5.6.2.2) Mus musculus (Mouse) double-strand break repair involved in meiotic recombination [GO:1990918]; homologous chromosome pairing at meiosis [GO:0007129]; male meiosis I [GO:0007141]; meiotic DNA double-strand break formation [GO:0042138]; meiotic DNA double-strand break processing [GO:0000706]; meiotic telomere clustering [GO:0045141]; oogenesis [GO:0048477]; ovarian follicle development [GO:0001541]; protein localization to chromosome [GO:0034502]; reciprocal meiotic recombination [GO:0007131]; spermatid development [GO:0007286]; synaptonemal complex assembly [GO:0007130] GO:0000228; GO:0000706; GO:0000781; GO:0001541; GO:0003677; GO:0003918; GO:0005524; GO:0005654; GO:0007129; GO:0007130; GO:0007131; GO:0007141; GO:0007286; GO:0016787; GO:0034502; GO:0042138; GO:0045141; GO:0046872; GO:0048477; GO:1990918 11389 XM_044321536.1 0 0 9 1 32 NA NA NA NA NA NA 11390 XR_003827915.1 29 34 56 30 35 NA NA NA NA NA NA 11391 XR_006394493.1 9 0 5 3 0 NA NA NA NA NA NA 11392 XM_029343209.2 9 21 106 0 57 Q9Z142 8.13e-63 Transmembrane protein 33 (Protein DB83) Rattus norvegicus (Rat) endoplasmic reticulum tubular network organization [GO:0071786]; innate immune response [GO:0045087]; membrane organization [GO:0061024]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of PERK-mediated unfolded protein response [GO:1903899]; regulation of endoplasmic reticulum tubular network organization [GO:1903371]; response to endoplasmic reticulum stress [GO:0034976] GO:0005635; GO:0005783; GO:0005789; GO:0034976; GO:0042470; GO:0045087; GO:0061024; GO:0071786; GO:1903371; GO:1903896; GO:1903899 11393 XM_029346066.2 313 187 183 500 347 NA NA NA NA NA NA 11394 XM_044323267.1 31 1 20 12 36 NA NA NA NA NA NA 11395 XM_044312121.1 5 0 13 0 0 NA NA NA NA NA NA 11396 XR_003825764.2 0 16 18 32 0 NA NA NA NA NA NA 11397 XM_029329148.2 5 0 212 1 0 Q12802 7.4e-82 A-kinase anchor protein 13 (AKAP-13) (AKAP-Lbc) (Breast cancer nuclear receptor-binding auxiliary protein) (Guanine nucleotide exchange factor Lbc) (Human thyroid-anchoring protein 31) (Lymphoid blast crisis oncogene) (LBC oncogene) (Non-oncogenic Rho GTPase-specific GTP exchange factor) (Protein kinase A-anchoring protein 13) (PRKA13) (p47) Homo sapiens (Human) adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process [GO:0086023]; adrenergic receptor signaling pathway [GO:0071875]; bone development [GO:0060348]; cardiac muscle cell differentiation [GO:0055007]; cell growth involved in cardiac muscle cell development [GO:0061049]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; nuclear export [GO:0051168]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Rho protein signal transduction [GO:0035025]; regulation of Rho protein signal transduction [GO:0035023]; regulation of sarcomere organization [GO:0060297]; regulation of small GTPase mediated signal transduction [GO:0051056] GO:0005078; GO:0005085; GO:0005634; GO:0005829; GO:0005938; GO:0007186; GO:0007507; GO:0016020; GO:0031267; GO:0035023; GO:0035025; GO:0043123; GO:0043406; GO:0046872; GO:0048471; GO:0051018; GO:0051056; GO:0051168; GO:0055007; GO:0060090; GO:0060297; GO:0060348; GO:0061049; GO:0071875; GO:0086023 11398 XM_044327569.1 180 112 200 328 246 B2RY50 5.07e-140 Outer dynein arm-docking complex subunit 2 (Armadillo repeat-containing protein 4) Mus musculus (Mouse) cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; outer dynein arm assembly [GO:0036158]; regulation of cilium beat frequency [GO:0003356]; ventricular system development [GO:0021591] GO:0003341; GO:0003356; GO:0005930; GO:0007368; GO:0007507; GO:0021591; GO:0036158; GO:0097546 11399 XM_029332208.2 0 27 36 0 1 NA NA NA NA NA NA 11400 XM_044314999.1 10 12 35 86 53 Q96LW4 5.48e-100 DNA-directed primase/polymerase protein (hPrimpol1) (EC 2.7.7.-) (Coiled-coil domain-containing protein 111) Homo sapiens (Human) error-prone translesion synthesis [GO:0042276]; mitochondrial DNA repair [GO:0043504]; mitochondrial DNA replication [GO:0006264]; R-loop processing [GO:0062176]; replication fork processing [GO:0031297]; response to UV [GO:0009411]; translesion synthesis [GO:0019985] GO:0000428; GO:0003682; GO:0003887; GO:0003896; GO:0005634; GO:0005657; GO:0005759; GO:0006264; GO:0008270; GO:0009411; GO:0019985; GO:0030145; GO:0031297; GO:0042276; GO:0043504; GO:0062176 11401 XM_029349589.2 0 0 44 128 0 NA NA NA NA NA NA 11402 XM_029329366.2 88 100 103 149 156 Q2S1V4 8.45e-179 Tryptophanase (EC 4.1.99.1) (L-tryptophan indole-lyase) (TNase) Salinibacter ruber (strain DSM 13855 / M31) NA GO:0009034 11403 XM_029349983.2 11 0 0 4 11 NA NA NA NA NA NA 11404 XM_029333689.2 78 149 50 94 27 O96952 2.14e-24 Thioredoxin (Trx) Geodia cydonium (Sponge) NA GO:0005737; GO:0015035 11405 XM_029345751.2 14505 15429 8900 13617 11836 P50395 1.73e-177 Rab GDP dissociation inhibitor beta (Rab GDI beta) (Guanosine diphosphate dissociation inhibitor 2) (GDI-2) Homo sapiens (Human) negative regulation of cilium assembly [GO:1902018]; negative regulation of protein localization to cilium [GO:1903565]; protein transport [GO:0015031]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192] GO:0003723; GO:0005093; GO:0005096; GO:0005576; GO:0005737; GO:0005794; GO:0005829; GO:0005925; GO:0007165; GO:0007264; GO:0015031; GO:0016020; GO:0016192; GO:0031267; GO:0031982; GO:0034774; GO:0035578; GO:0045202; GO:0070062; GO:1902018; GO:1903565 11406 XR_006394424.1 138 535 82 126 148 O75897 1.36e-51 Sulfotransferase 1C4 (ST1C4) (EC 2.8.2.1) (Sulfotransferase 1C2) (SULT1C#2) Homo sapiens (Human) 3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; doxorubicin metabolic process [GO:0044598]; ethanol catabolic process [GO:0006068]; flavonoid metabolic process [GO:0009812]; sulfation [GO:0051923]; xenobiotic metabolic process [GO:0006805] GO:0004062; GO:0005737; GO:0005829; GO:0006068; GO:0006805; GO:0008146; GO:0009812; GO:0044598; GO:0050427; GO:0051923 11407 XM_044328538.1 226 200 248 250 113 Q96KE9 7.72e-82 BTB/POZ domain-containing protein 6 (Lens BTB domain protein) Homo sapiens (Human) neurogenesis [GO:0022008] GO:0005829; GO:0022008 11408 XM_029348290.2 0 80 0 0 0 Q91WI7 4.12e-33 KICSTOR complex protein ITFG2 (Integrin-alpha FG-GAP repeat-containing protein 2) Mus musculus (Mouse) cellular response to amino acid starvation [GO:0034198]; cellular response to glucose starvation [GO:0042149]; germinal center B cell differentiation [GO:0002314]; negative regulation of TORC1 signaling [GO:1904262]; regulation of TOR signaling [GO:0032006] GO:0002314; GO:0005654; GO:0005765; GO:0005829; GO:0032006; GO:0034198; GO:0042149; GO:0140007; GO:1904262 11409 XM_029348290.2 0 80 0 0 0 Q91WI7 3.5e-23 KICSTOR complex protein ITFG2 (Integrin-alpha FG-GAP repeat-containing protein 2) Mus musculus (Mouse) cellular response to amino acid starvation [GO:0034198]; cellular response to glucose starvation [GO:0042149]; germinal center B cell differentiation [GO:0002314]; negative regulation of TORC1 signaling [GO:1904262]; regulation of TOR signaling [GO:0032006] GO:0002314; GO:0005654; GO:0005765; GO:0005829; GO:0032006; GO:0034198; GO:0042149; GO:0140007; GO:1904262 11410 XM_044324601.1 0 2 9 0 0 NA NA NA NA NA NA 11411 XM_044318006.1 85 0 0 12 27 NA NA NA NA NA NA 11412 XR_006392983.1 41 2 25 5 151 NA NA NA NA NA NA 11413 XR_006391455.1 11 9 34 12 18 NA NA NA NA NA NA 11414 XM_029337616.2 888 956 487 590 483 Q5R7X9 4.82e-144 Cell cycle checkpoint protein RAD1 (EC 3.1.11.2) (DNA repair exonuclease rad1 homolog) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cellular response to ionizing radiation [GO:0071479]; DNA damage checkpoint signaling [GO:0000077]; DNA repair [GO:0006281]; meiotic recombination checkpoint signaling [GO:0051598] GO:0000077; GO:0005654; GO:0005694; GO:0006281; GO:0008408; GO:0008853; GO:0051598; GO:0071479 11415 XM_044314337.1 0 0 0 0 7 P35061 4.97e-85 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 11416 XM_044328272.1 181 179 151 247 152 Q4G1G8 6.88e-21 Cholesterol 25-hydroxylase (EC 1.14.99.38) (Cholesterol 25-monooxygenase) Sus scrofa (Pig) B cell chemotaxis [GO:0035754]; cholesterol metabolic process [GO:0008203]; negative regulation of fusion of virus membrane with host plasma membrane [GO:1903914]; response to type I interferon [GO:0034340]; sterol biosynthetic process [GO:0016126] GO:0000254; GO:0001567; GO:0005506; GO:0005789; GO:0008203; GO:0008395; GO:0016020; GO:0016126; GO:0016491; GO:0034340; GO:0035754; GO:1903914 11417 XR_003824727.2 50 62 119 143 199 NA NA NA NA NA NA 11418 XM_029334071.2 0 0 0 198 0 NA NA NA NA NA NA 11419 XM_044307342.1 19 13 22 3 22 P70490 4.64e-23 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 11420 XM_029342404.2 22 54 37 71 36 P00774 7.23e-47 Chymotrypsin-like elastase family member 2A (EC 3.4.21.71) (Elastase-2) (Elastase-2A) Rattus norvegicus (Rat) insulin catabolic process [GO:1901143]; proteolysis [GO:0006508]; regulation of insulin secretion [GO:0050796]; regulation of platelet aggregation [GO:0090330]; response to insulin [GO:0032868] GO:0004175; GO:0004252; GO:0005576; GO:0005615; GO:0006508; GO:0017171; GO:0032868; GO:0036457; GO:0050796; GO:0090330; GO:1901143 11421 XM_044313120.1 9 29 15 61 63 NA NA NA NA NA NA 11422 XM_044320374.1 309 186 165 289 169 NA NA NA NA NA NA 11423 XM_044325474.1 50 0 25 0 18 Q80SY4 2.03e-49 E3 ubiquitin-protein ligase MIB1 (EC 2.3.2.27) (DAPK-interacting protein 1) (DIP-1) (Mind bomb homolog 1) (RING-type E3 ubiquitin transferase MIB1) Mus musculus (Mouse) blood vessel development [GO:0001568]; endocytosis [GO:0006897]; heart development [GO:0007507]; heart looping [GO:0001947]; in utero embryonic development [GO:0001701]; negative regulation of neuron differentiation [GO:0045665]; neural tube formation [GO:0001841]; neuron differentiation [GO:0030182]; Notch signaling pathway [GO:0007219]; positive regulation of endocytosis [GO:0045807]; protein ubiquitination [GO:0016567]; somitogenesis [GO:0001756]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0001568; GO:0001701; GO:0001756; GO:0001841; GO:0001947; GO:0004842; GO:0005737; GO:0005813; GO:0005886; GO:0006511; GO:0006897; GO:0007219; GO:0007507; GO:0008270; GO:0014069; GO:0016567; GO:0030182; GO:0031410; GO:0045665; GO:0045807 11424 XM_029357718.2 203 414 157 346 367 NA NA NA NA NA NA 11425 XR_006393784.1 2 7 2 9 4 NA NA NA NA NA NA 11426 XR_003825653.2 0 0 0 9 3 NA NA NA NA NA NA 11427 XM_029352753.2 0 368 0 0 510 NA NA NA NA NA NA 11428 XR_006392609.1 6 11 2 0 0 NA NA NA NA NA NA 11429 XR_006396094.1 6 5 1 2 86 NA NA NA NA NA NA 11430 XM_044308402.1 38 20 71 22 208 Q5VXU9 9.49e-24 Protein shortage in chiasmata 1 ortholog (EC 3.6.-.-) (Protein ZIP2 homolog) (MZIP2) Homo sapiens (Human) reciprocal meiotic recombination [GO:0007131]; resolution of meiotic recombination intermediates [GO:0000712]; synaptonemal complex assembly [GO:0007130] GO:0000712; GO:0000794; GO:0003697; GO:0005694; GO:0007130; GO:0007131; GO:0016887 11431 XM_029348137.2 0 0 0 0 49 P49338 2.86e-114 Protein Wnt-4 (XWnt-4) Xenopus laevis (African clawed frog) embryonic pattern specification [GO:0009880]; glomus development [GO:0072013]; nephrostome development [GO:0039018]; pronephric nephron tubule development [GO:0039020]; Wnt signaling pathway [GO:0016055] GO:0005102; GO:0005576; GO:0009880; GO:0016055; GO:0039018; GO:0039020; GO:0072013 11432 XM_029356017.2 85 39 64 56 74 NA NA NA NA NA NA 11433 XM_044317133.1 54 41 297 136 43 Q9DB41 6.31e-98 Mitochondrial glutamate carrier 2 (GC-2) (Glutamate/H(+) symporter 2) (Solute carrier family 25 member 18) Mus musculus (Mouse) aspartate transmembrane transport [GO:0015810]; L-glutamate transmembrane transport [GO:0015813]; malate-aspartate shuttle [GO:0043490] GO:0005280; GO:0005313; GO:0005743; GO:0015183; GO:0015810; GO:0015813; GO:0022857; GO:0043490 11434 XM_029341434.2 6 11 0 0 0 NA NA NA NA NA NA 11435 XM_044319807.1 109 0 160 37 273 P97292 6.32e-21 Histamine H2 receptor (H2R) (HH2R) (Gastric receptor I) Mus musculus (Mouse) chemical synaptic transmission [GO:0007268]; digestive tract development [GO:0048565]; epithelial cell morphogenesis [GO:0003382]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; gastric acid secretion [GO:0001696]; gastrin-induced gastric acid secretion [GO:0001698]; gland development [GO:0048732]; histamine-induced gastric acid secretion [GO:0001697]; memory [GO:0007613]; negative regulation of arachidonic acid secretion [GO:1900139]; positive regulation of vasoconstriction [GO:0045907]; regulation of synaptic plasticity [GO:0048167]; toxin transport [GO:1901998]; visual learning [GO:0008542] GO:0001696; GO:0001697; GO:0001698; GO:0003382; GO:0004969; GO:0004993; GO:0005886; GO:0007187; GO:0007268; GO:0007613; GO:0008542; GO:0016020; GO:0030425; GO:0030594; GO:0045202; GO:0045907; GO:0048167; GO:0048565; GO:0048732; GO:1900139; GO:1901363; GO:1901998 11436 XM_029339826.2 1460 1078 362 3554 5327 G8HTB6 1.12e-38 ZP domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 11437 XM_044323616.1 0 0 0 7 0 NA NA NA NA NA NA 11438 XM_029344146.2 419 172 256 367 417 Q38PU3 1.22e-84 Glutamate receptor ionotropic, kainate 2 (GluK2) (Glutamate receptor 6) (GluR-6) (GluR6) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) detection of cold stimulus involved in thermoception [GO:0120169] GO:0004970; GO:0005234; GO:0030424; GO:0043197; GO:0045211; GO:0120169 11439 XR_006391757.1 47 12 0 31 5 NA NA NA NA NA NA 11440 XM_029340582.2 392 289 292 179 135 NA NA NA NA NA NA 11441 XM_029344753.2 376 59 224 139 256 Q09225 2.03e-45 Nose resistant to fluoxetine protein 6 (Protein nrf-6) Caenorhabditis elegans lipid transport [GO:0006869] GO:0006869; GO:0008289; GO:0016020; GO:0016747 11442 XM_044308203.1 22 116 105 62 130 NA NA NA NA NA NA 11443 XR_006397465.1 0 0 0 4 9 NA NA NA NA NA NA 11444 XM_029334640.2 137 78 148 135 171 Q6R3M4 1.81e-107 DNA polymerase iota (EC 2.7.7.7) (Rad30 homolog B) Mus musculus (Mouse) cellular response to UV-C [GO:0071494]; DNA replication [GO:0006260]; translesion synthesis [GO:0019985] GO:0003684; GO:0003887; GO:0006260; GO:0016607; GO:0019985; GO:0036464; GO:0046872; GO:0071494 11445 XM_029346331.2 115 58 37 51 44 E7FAM5 2.27e-128 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 11446 XM_044311034.1 70 42 127 149 313 NA NA NA NA NA NA 11447 XM_029350116.2 0 83 21 0 89 NA NA NA NA NA NA 11448 XM_029331315.2 1212 1245 734 1493 1154 Q18969 4.44e-64 NA NA NA NA 11449 XM_044317978.1 666 455 191 620 1 Q9US12 3.53e-22 Putative zinc metalloproteinase C607.06c (EC 3.4.24.-) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) proteolysis [GO:0006508] GO:0005634; GO:0005829; GO:0006508; GO:0008237; GO:0030246; GO:0032153; GO:0046872 11450 XM_044329171.1 0 2 14 3 14 NA NA NA NA NA NA 11451 XM_029338986.2 18 10 6 4 1 NA NA NA NA NA NA 11452 XM_029349231.2 69 54 27 52 30 NA NA NA NA NA NA 11453 XM_044316449.1 11 0 0 0 13 NA NA NA NA NA NA 11454 XM_044327275.1 14 0 10 4 6 NA NA NA NA NA NA 11455 XR_006395853.1 14 14 14 7 35 NA NA NA NA NA NA 11456 XM_044326748.1 46 1 8 0 21 NA NA NA NA NA NA 11457 XM_029337159.2 13 23 10 38 18 Q9EP86 8.12e-22 Neuropeptide FF receptor 1 (G-protein coupled receptor 147) (RFamide-related peptide receptor OT7T022) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0005886; GO:0005929; GO:0007186; GO:0008188; GO:0042277 11458 XM_044309386.1 1921 1338 1079 961 529 NA NA NA NA NA NA 11459 XM_029324092.2 0 0 6 26 8 Q5M7N9 8.69e-80 Extended synaptotagmin-3 (E-Syt3) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) endoplasmic reticulum-plasma membrane tethering [GO:0061817]; lipid transport [GO:0006869] GO:0005789; GO:0005886; GO:0006869; GO:0008289; GO:0046872; GO:0061817; GO:0140268 11460 XM_044316831.1 10 13 26 0 177 NA NA NA NA NA NA 11461 XM_044325493.1 1 20 0 14 0 NA NA NA NA NA NA 11462 XM_044319424.1 4 10 15 6 20 NA NA NA NA NA NA 11463 XM_044323320.1 770 159 293 757 209 Q8R4B8 1.46e-35 NACHT, LRR and PYD domains-containing protein 3 (EC 3.6.4.-) (Cold autoinflammatory syndrome 1 protein homolog) (Cryopyrin) (Mast cell maturation-associated-inducible protein 1) (PYRIN-containing APAF1-like protein 1) Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptidoglycan [GO:0071224]; cellular response to virus [GO:0098586]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of biotic stimulus [GO:0009595]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; NLRP3 inflammasome complex assembly [GO:0044546]; osmosensory signaling pathway [GO:0007231]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-13 production [GO:0032736]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-5 production [GO:0032754]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T-helper 17 cell differentiation [GO:2000321]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type 2 immune response [GO:0002830]; protein homooligomerization [GO:0051260]; pyroptosis [GO:0070269]; regulation of inflammatory response [GO:0050727]; response to ethanol [GO:0045471]; response to organic cyclic compound [GO:0014070] GO:0000139; GO:0002221; GO:0002523; GO:0002526; GO:0002674; GO:0002720; GO:0002830; GO:0005524; GO:0005576; GO:0005634; GO:0005737; GO:0005739; GO:0005783; GO:0005815; GO:0005829; GO:0006919; GO:0006954; GO:0007231; GO:0009595; GO:0014070; GO:0016020; GO:0016887; GO:0031021; GO:0032088; GO:0032691; GO:0032731; GO:0032736; GO:0032753; GO:0032754; GO:0035591; GO:0042802; GO:0043280; GO:0043531; GO:0043565; GO:0044546; GO:0045087; GO:0045471; GO:0045630; GO:0045944; GO:0050727; GO:0050728; GO:0050729; GO:0050830; GO:0051092; GO:0051260; GO:0051607; GO:0061702; GO:0070269; GO:0070273; GO:0071222; GO:0071224; GO:0072559; GO:0098586; GO:0140297; GO:0140299; GO:1901223; GO:1901981; GO:2000321; GO:2000553 11464 XM_044319681.1 16 0 27 0 82 Q69Z28 2.57e-159 A disintegrin and metalloproteinase with thrombospondin motifs 16 (ADAM-TS 16) (ADAM-TS16) (ADAMTS-16) (EC 3.4.24.-) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; extracellular matrix organization [GO:0030198]; male gamete generation [GO:0048232]; proteolysis [GO:0006508]; regulation of cilium assembly [GO:1902017]; regulation of systemic arterial blood pressure [GO:0003073] GO:0001658; GO:0003073; GO:0004222; GO:0005576; GO:0006508; GO:0030198; GO:0031012; GO:0046872; GO:0048232; GO:1902017 11465 XM_044323009.1 8391 5252 5282 8812 8542 B8UU78 0 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 11466 XM_044323027.1 354 734 823 1431 1337 P02466 3.6e-46 Collagen alpha-2(I) chain (Alpha-2 type I collagen) Rattus norvegicus (Rat) blood vessel development [GO:0001568]; bone mineralization [GO:0030282]; cellular response to amino acid stimulus [GO:0071230]; cellular response to organic substance [GO:0071310]; cellular response to retinoic acid [GO:0071300]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; extracellular matrix assembly [GO:0085029]; extracellular matrix organization [GO:0030198]; protein heterotrimerization [GO:0070208]; regulation of blood pressure [GO:0008217]; response to norepinephrine [GO:0071873]; Rho protein signal transduction [GO:0007266]; skeletal system development [GO:0001501]; skin morphogenesis [GO:0043589]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001501; GO:0001568; GO:0002020; GO:0005201; GO:0005576; GO:0005581; GO:0005584; GO:0005615; GO:0007179; GO:0007266; GO:0008217; GO:0030198; GO:0030199; GO:0030282; GO:0030674; GO:0031012; GO:0032963; GO:0042802; GO:0043589; GO:0046332; GO:0046872; GO:0048407; GO:0062023; GO:0070208; GO:0071230; GO:0071300; GO:0071310; GO:0071873; GO:0085029; GO:0097067 11467 XM_029338396.2 511 468 344 496 274 Q6DRD9 1.86e-69 Protein ABHD11 (EC 3.-.-.-) (Alpha/beta hydrolase domain-containing protein 11) (Abhydrolase domain-containing protein 11) (Williams-Beuren syndrome chromosomal region 21 protein homolog) Danio rerio (Zebrafish) (Brachydanio rerio) cellular lipid metabolic process [GO:0044255] GO:0005739; GO:0016787; GO:0044255 11468 XM_029345883.2 114 167 94 93 28 NA NA NA NA NA NA 11469 XM_044323049.1 0 0 1 0 6 P54132 3.01e-27 RecQ-like DNA helicase BLM (EC 3.6.4.12) (Bloom syndrome protein) (DNA helicase, RecQ-like type 2) (RecQ2) (RecQ protein-like 3) Homo sapiens (Human) cellular response to camptothecin [GO:0072757]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hydroxyurea [GO:0072711]; cellular response to ionizing radiation [GO:0071479]; DNA double-strand break processing [GO:0000729]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724]; G-quadruplex DNA unwinding [GO:0044806]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; negative regulation of cell division [GO:0051782]; negative regulation of DNA recombination [GO:0045910]; positive regulation of DNA-templated transcription [GO:0045893]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of DNA-templated DNA replication [GO:0090329]; replication fork processing [GO:0031297]; replication fork protection [GO:0048478]; resolution of recombination intermediates [GO:0071139]; response to X-ray [GO:0010165]; t-circle formation [GO:0090656]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; telomeric D-loop disassembly [GO:0061820] GO:0000079; GO:0000228; GO:0000400; GO:0000403; GO:0000405; GO:0000723; GO:0000724; GO:0000729; GO:0000800; GO:0002039; GO:0003677; GO:0003678; GO:0003697; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0005657; GO:0005694; GO:0005730; GO:0005737; GO:0005829; GO:0006260; GO:0006268; GO:0006281; GO:0006310; GO:0006974; GO:0007095; GO:0008094; GO:0008270; GO:0009378; GO:0010165; GO:0016363; GO:0016605; GO:0016887; GO:0031297; GO:0031422; GO:0032201; GO:0032508; GO:0032991; GO:0042802; GO:0042803; GO:0043138; GO:0044806; GO:0045893; GO:0045910; GO:0048478; GO:0051259; GO:0051260; GO:0051782; GO:0051880; GO:0061749; GO:0061820; GO:0061821; GO:0061849; GO:0071139; GO:0071479; GO:0072711; GO:0072757; GO:0090329; GO:0090656; GO:0140677; GO:1905773; GO:1990814 11470 XM_044315918.1 38 0 63 10 90 NA NA NA NA NA NA 11471 XM_029328898.2 2260 3024 2506 2477 2417 NA NA NA NA NA NA 11472 XM_029330038.2 2324 1802 1288 2180 2315 Q2KIA5 0 Dynamin-1-like protein (EC 3.6.5.5) Bos taurus (Bovine) calcium ion transport [GO:0006816]; dynamin family protein polymerization involved in mitochondrial fission [GO:0003374]; endocytosis [GO:0006897]; heart contraction [GO:0060047]; intracellular distribution of mitochondria [GO:0048312]; membrane fusion [GO:0061025]; mitochondrial fission [GO:0000266]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; mitochondrial membrane fission [GO:0090149]; mitochondrion morphogenesis [GO:0070584]; mitocytosis [GO:0160040]; necroptotic process [GO:0070266]; peroxisome fission [GO:0016559]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of protein secretion [GO:0050714]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; protein complex oligomerization [GO:0051259]; protein localization to mitochondrion [GO:0070585]; regulation of ATP metabolic process [GO:1903578]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of gene expression [GO:0010468]; regulation of peroxisome organization [GO:1900063]; regulation of ubiquitin protein ligase activity [GO:1904666]; release of cytochrome c from mitochondria [GO:0001836]; rhythmic process [GO:0048511] GO:0000266; GO:0001836; GO:0003374; GO:0003924; GO:0005525; GO:0005737; GO:0005739; GO:0005741; GO:0005777; GO:0005783; GO:0005794; GO:0005829; GO:0005874; GO:0005903; GO:0005905; GO:0006816; GO:0006897; GO:0008017; GO:0008289; GO:0010468; GO:0016020; GO:0016559; GO:0030672; GO:0030742; GO:0031267; GO:0031625; GO:0032991; GO:0042802; GO:0042803; GO:0043653; GO:0048312; GO:0048471; GO:0048511; GO:0050714; GO:0051259; GO:0060047; GO:0061025; GO:0070266; GO:0070584; GO:0070585; GO:0090023; GO:0090141; GO:0090149; GO:0090200; GO:0099073; GO:0160040; GO:1900063; GO:1903146; GO:1903578; GO:1904666; GO:2001244 11473 XR_006395089.1 18 2 8 0 3 NA NA NA NA NA NA 11474 XM_029329379.2 324 232 119 714 430 NA NA NA NA NA NA 11475 XM_044328421.1 4 2 0 5 11 NA NA NA NA NA NA 11476 XM_029328455.2 709 308 223 443 358 NA NA NA NA NA NA 11477 XR_006395429.1 113 26 156 207 48 O82504 4.82e-25 RNA-dependent RNA polymerase 2 (AtRDRP2) (EC 2.7.7.48) (Protein SILENCING MOVEMENT DEFICIENT 1) (RNA-directed RNA polymerase 2) Arabidopsis thaliana (Mouse-ear cress) defense response to fungus [GO:0050832]; RNA biosynthetic process [GO:0032774]; RNA-templated transcription [GO:0001172]; siRNA processing [GO:0030422]; siRNA-mediated long-distance post-transcriptional gene silencing [GO:0010495] GO:0001172; GO:0003727; GO:0003968; GO:0005634; GO:0005654; GO:0005730; GO:0010495; GO:0030422; GO:0031380; GO:0032774; GO:0046872; GO:0050832; GO:0071667 11478 XM_044313420.1 4 0 0 2 8 NA NA NA NA NA NA 11479 XR_006397021.1 0 0 66 39 110 NA NA NA NA NA NA 11480 XM_029330106.2 528 141 119 270 173 A7WM73 1.15e-40 Beta-hexosaminidase 1 (EC 3.2.1.52) (Beta-GlcNAcase 1) (Beta-N-acetylhexosaminidase 1) (Beta-hexosaminidase 2) (AtHEX2) (N-acetyl-beta-glucosaminidase 1) Arabidopsis thaliana (Mouse-ear cress) carbohydrate metabolic process [GO:0005975]; glycosaminoglycan metabolic process [GO:0030203] GO:0000325; GO:0004563; GO:0005773; GO:0005975; GO:0015929; GO:0016020; GO:0030203; GO:0099503; GO:0102148 11481 XM_044312805.1 62 0 7 0 0 Q17RS7 1.55e-67 Flap endonuclease GEN homolog 1 (EC 3.1.-.-) Homo sapiens (Human) double-strand break repair via homologous recombination [GO:0000724]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; regulation of centrosome duplication [GO:0010824]; replication fork processing [GO:0031297]; resolution of mitotic recombination intermediates [GO:0071140]; resolution of recombination intermediates [GO:0071139] GO:0000287; GO:0000400; GO:0000724; GO:0005654; GO:0005813; GO:0008821; GO:0010824; GO:0017108; GO:0031297; GO:0042803; GO:0071139; GO:0071140; GO:0090267 11482 XR_006396730.1 4 11 3 36 23 NA NA NA NA NA NA 11483 XM_029327169.2 1241 778 470 736 444 P23359 2.57e-36 Bone morphogenetic protein 7 (BMP-7) (Osteogenic protein 1) (OP-1) Mus musculus (Mouse) allantois development [GO:1905069]; ameloblast differentiation [GO:0036305]; anatomical structure formation involved in morphogenesis [GO:0048646]; animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; BMP signaling pathway [GO:0030509]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle tissue development [GO:0048738]; cardiac septum morphogenesis [GO:0060411]; cartilage development [GO:0051216]; cell development [GO:0048468]; cell population proliferation [GO:0008283]; cellular response to BMP stimulus [GO:0071773]; chorio-allantoic fusion [GO:0060710]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic skeletal joint morphogenesis [GO:0060272]; endocardial cushion formation [GO:0003272]; epithelial cell differentiation [GO:0030855]; eye development [GO:0001654]; heart trabecula morphogenesis [GO:0061384]; hindbrain development [GO:0030902]; kidney development [GO:0001822]; mesenchymal cell apoptotic process involved in nephron morphogenesis [GO:1901145]; mesenchymal cell differentiation [GO:0048762]; mesenchyme development [GO:0060485]; mesoderm formation [GO:0001707]; metanephric mesenchymal cell proliferation involved in metanephros development [GO:0072136]; metanephric mesenchyme morphogenesis [GO:0072133]; monocyte aggregation [GO:0070487]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell death [GO:0060548]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of glomerular mesangial cell proliferation [GO:0072125]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis [GO:0072040]; negative regulation of mitotic nuclear division [GO:0045839]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of phosphorylation [GO:0042326]; negative regulation of prostatic bud formation [GO:0060686]; nephrogenic mesenchyme morphogenesis [GO:0072134]; neural fold elevation formation [GO:0021502]; neuron projection morphogenesis [GO:0048812]; odontogenesis of dentin-containing tooth [GO:0042475]; ossification [GO:0001503]; pattern specification process [GO:0007389]; pericardium morphogenesis [GO:0003344]; pharyngeal system development [GO:0060037]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone mineralization [GO:0030501]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis [GO:1905312]; positive regulation of cell death [GO:0010942]; positive regulation of dendrite development [GO:1900006]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial cell differentiation [GO:0030858]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of gene expression [GO:0010628]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of hyaluranon cable assembly [GO:1900106]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to nucleus [GO:0034504]; regulation of branching involved in prostate gland morphogenesis [GO:0060687]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of phosphorylation [GO:0042325]; response to estradiol [GO:0032355]; response to peptide hormone [GO:0043434]; response to vitamin D [GO:0033280]; salivary gland morphogenesis [GO:0007435]; SMAD protein signal transduction [GO:0060395]; steroid hormone mediated signaling pathway [GO:0043401]; tube morphogenesis [GO:0035239]; ureteric bud development [GO:0001657] GO:0001503; GO:0001654; GO:0001657; GO:0001707; GO:0001822; GO:0003272; GO:0003344; GO:0005125; GO:0005615; GO:0007389; GO:0007411; GO:0007435; GO:0008083; GO:0008201; GO:0008283; GO:0008285; GO:0009880; GO:0009887; GO:0010628; GO:0010718; GO:0010800; GO:0010862; GO:0010942; GO:0021502; GO:0030326; GO:0030501; GO:0030509; GO:0030855; GO:0030858; GO:0030902; GO:0031982; GO:0032355; GO:0033280; GO:0034116; GO:0034504; GO:0035239; GO:0036305; GO:0042325; GO:0042326; GO:0042475; GO:0043065; GO:0043401; GO:0043407; GO:0043434; GO:0045665; GO:0045666; GO:0045669; GO:0045746; GO:0045786; GO:0045839; GO:0045892; GO:0045893; GO:0045944; GO:0048468; GO:0048593; GO:0048596; GO:0048646; GO:0048738; GO:0048754; GO:0048762; GO:0048812; GO:0050768; GO:0051216; GO:0060037; GO:0060272; GO:0060391; GO:0060393; GO:0060395; GO:0060411; GO:0060445; GO:0060485; GO:0060548; GO:0060686; GO:0060687; GO:0060710; GO:0061384; GO:0062023; GO:0070487; GO:0070700; GO:0071773; GO:0072040; GO:0072125; GO:0072133; GO:0072134; GO:0072136; GO:0090336; GO:1900006; GO:1900106; GO:1901145; GO:1905069; GO:1905312 11484 XM_029356045.2 58 22 52 101 128 P04274 3.18e-21 Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor) Mesocricetus auratus (Golden hamster) activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; bone resorption [GO:0045453]; brown fat cell differentiation [GO:0050873]; cellular response to amyloid-beta [GO:1904646]; desensitization of G protein-coupled receptor signaling pathway by arrestin [GO:0002032]; diet induced thermogenesis [GO:0002024]; heat generation [GO:0031649]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of smooth muscle contraction [GO:0045986]; norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0002025]; positive regulation of AMPA receptor activity [GO:2000969]; positive regulation of autophagosome maturation [GO:1901098]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of lipophagy [GO:1904504]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mini excitatory postsynaptic potential [GO:0061885]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor-mediated endocytosis [GO:0006898]; regulation of sodium ion transport [GO:0002028]; response to cold [GO:0009409]; smooth muscle contraction [GO:0006939]; transcription by RNA polymerase II [GO:0006366] GO:0001540; GO:0002024; GO:0002025; GO:0002028; GO:0002032; GO:0004941; GO:0005634; GO:0005769; GO:0005794; GO:0006366; GO:0006898; GO:0006939; GO:0007189; GO:0007190; GO:0008179; GO:0009409; GO:0010739; GO:0015459; GO:0016324; GO:0030501; GO:0031649; GO:0040015; GO:0042803; GO:0043235; GO:0043410; GO:0044877; GO:0045453; GO:0045944; GO:0045986; GO:0050873; GO:0051380; GO:0061885; GO:0071902; GO:0098992; GO:0120162; GO:1901098; GO:1904504; GO:1904646; GO:2000969 11485 XR_006393874.1 112 36 53 15 50 NA NA NA NA NA NA 11486 XR_006393576.1 0 0 5 10 30 NA NA NA NA NA NA 11487 XM_044312190.1 10 0 0 52 67 NA NA NA NA NA NA 11488 XR_006396503.1 78 66 66 33 33 NA NA NA NA NA NA 11489 XM_044315116.1 4 9 38 2 179 Q9VBW3 7.48e-59 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 11490 XM_029327843.2 46 84 246 765 205 Q5ZL23 1.38e-66 Amyloid beta A4 precursor protein-binding family B member 1-interacting protein (APBB1-interacting protein 1) Gallus gallus (Chicken) signal transduction [GO:0007165] GO:0005829; GO:0005856; GO:0005886; GO:0007165 11491 XM_029336357.2 293 243 136 153 237 Q9CR48 1.2e-35 DNA damage-regulated autophagy modulator protein 2 (Transmembrane protein 77) Mus musculus (Mouse) apoptotic process [GO:0006915]; autophagy [GO:0006914]; photoreceptor cell maintenance [GO:0045494]; regulation of autophagy [GO:0010506]; visual perception [GO:0007601] GO:0001917; GO:0005737; GO:0005764; GO:0005765; GO:0005794; GO:0006914; GO:0006915; GO:0007601; GO:0010506; GO:0016324; GO:0043231; GO:0045494 11492 XM_029334045.2 21 56 14 18 51 Q00168 4.4e-59 Calcium/calmodulin-dependent protein kinase type II alpha chain (CaM-kinase II alpha chain) (EC 2.7.11.17) Drosophila melanogaster (Fruit fly) cellular response to starvation [GO:0009267]; chemical synaptic transmission [GO:0007268]; courtship behavior [GO:0007619]; learning or memory [GO:0007611]; long-term memory [GO:0007616]; male courtship behavior [GO:0008049]; negative regulation of cytokine production [GO:0001818]; negative regulation of lipid storage [GO:0010888]; neuromuscular junction development [GO:0007528]; peptidyl-threonine autophosphorylation [GO:1990443]; positive regulation of synaptic transmission, dopaminergic [GO:0032226]; protein phosphorylation [GO:0006468]; regulation of filopodium assembly [GO:0051489]; regulation of ovulation [GO:0060278]; regulation of synaptic assembly at neuromuscular junction [GO:0008582] GO:0001818; GO:0004674; GO:0004683; GO:0005516; GO:0005524; GO:0005737; GO:0006468; GO:0007268; GO:0007528; GO:0007611; GO:0007616; GO:0007619; GO:0008049; GO:0008582; GO:0009267; GO:0010888; GO:0030424; GO:0030425; GO:0032226; GO:0043005; GO:0045211; GO:0048786; GO:0051489; GO:0060278; GO:0106310; GO:1990443 11493 XR_006394057.1 386 234 0 19 438 NA NA NA NA NA NA 11494 XR_006395072.1 0 9 0 0 6 NA NA NA NA NA NA 11495 XM_044325809.1 20 0 6 108 21 NA NA NA NA NA NA 11496 XR_006395634.1 1015 1845 1415 867 2201 NA NA NA NA NA NA 11497 XM_044306886.1 8 0 0 0 16 Q9EQJ0 1.43e-126 Two pore calcium channel protein 1 (Voltage-dependent calcium channel protein TPC1) Mus musculus (Mouse) endocytosis involved in viral entry into host cell [GO:0075509]; positive regulation of autophagy [GO:0010508]; regulation of ion transmembrane transport [GO:0034765]; sodium ion transmembrane transport [GO:0035725] GO:0005244; GO:0005248; GO:0005765; GO:0010008; GO:0010508; GO:0015280; GO:0016020; GO:0019905; GO:0031901; GO:0034765; GO:0035725; GO:0036019; GO:0042802; GO:0042803; GO:0055038; GO:0072345; GO:0075509; GO:0080025; GO:0097682 11498 XM_044314896.1 0 1 171 2 28 Q9U6Y6 7.78e-111 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 11499 XM_044309776.1 349 475 545 435 734 NA NA NA NA NA NA 11500 XM_029337985.2 1459 738 1925 8640 4846 P57788 9.22e-36 Monocarboxylate transporter 4 (MCT 4) (Solute carrier family 16 member 3) Gallus gallus (Chicken) lactate transmembrane transport [GO:0035873]; pyruvate transmembrane transport [GO:1901475] GO:0005886; GO:0015650; GO:0016323; GO:0035873; GO:0050833; GO:1901475 11501 XM_029336767.2 837 554 426 341 315 Q8STF6 2.51e-43 Dystrophin-like protein 1 (Dyb-1-binding and CAPON-related protein) Caenorhabditis elegans locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; positive regulation of locomotion [GO:0040017]; regulation of oviposition [GO:0046662]; sarcomere organization [GO:0045214] GO:0007626; GO:0008307; GO:0016010; GO:0030235; GO:0030424; GO:0040017; GO:0045214; GO:0046662; GO:0046716; GO:0050998; GO:0055120 11502 XM_044314302.1 556 336 199 304 240 Q9BVL4 2.18e-165 Protein adenylyltransferase SelO, mitochondrial (EC 2.7.7.-) (EC 2.7.7.108) (Selenoprotein O) (SelO) Homo sapiens (Human) protein adenylylation [GO:0018117] GO:0005524; GO:0005694; GO:0005739; GO:0018117; GO:0046872; GO:0070733 11503 XM_044315765.1 5 5 5 25 9 NA NA NA NA NA NA 11504 XM_029324893.2 156 196 111 96 88 Q9C0H5 8.69e-153 Rho GTPase-activating protein 39 Homo sapiens (Human) postsynapse organization [GO:0099173]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] GO:0005096; GO:0005634; GO:0005737; GO:0005829; GO:0005856; GO:0007165; GO:0051056; GO:0098978; GO:0099173 11505 XM_029324893.2 156 196 111 96 88 Q9C0H5 2.2e-26 Rho GTPase-activating protein 39 Homo sapiens (Human) postsynapse organization [GO:0099173]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] GO:0005096; GO:0005634; GO:0005737; GO:0005829; GO:0005856; GO:0007165; GO:0051056; GO:0098978; GO:0099173 11506 XR_006397226.1 14 5 14 18 2 NA NA NA NA NA NA 11507 XR_003824589.2 126 84 139 112 80 NA NA NA NA NA NA 11508 XR_006394452.1 193 98 67 108 70 NA NA NA NA NA NA 11509 XM_044316697.1 196 98 131 87 0 NA NA NA NA NA NA 11510 XM_044314365.1 3 0 171 196 5 NA NA NA NA NA NA 11511 XR_003826866.2 15 0 17 3 68 NA NA NA NA NA NA 11512 XM_044318744.1 0 0 14 14 26 Q766D5 5.08e-61 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Mus musculus (Mouse) chondroitin sulfate biosynthetic process [GO:0030206] GO:0008376; GO:0030206; GO:0032580; GO:0033842; GO:0047238 11513 XM_044318744.1 0 0 14 14 26 Q766D5 1.95e-25 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Mus musculus (Mouse) chondroitin sulfate biosynthetic process [GO:0030206] GO:0008376; GO:0030206; GO:0032580; GO:0033842; GO:0047238 11514 XM_029347243.2 1507 1505 847 1212 711 Q792Q4 2.67e-52 Cysteine-rich PDZ-binding protein (Cysteine-rich interactor of PDZ three) (Cysteine-rich interactor of PDZ3) Rattus norvegicus (Rat) cytoplasmic microtubule organization [GO:0031122]; establishment of protein localization [GO:0045184]; protein localization to microtubule [GO:0035372]; regulation of postsynaptic density assembly [GO:0099151]; regulation of postsynaptic density protein 95 clustering [GO:1902897] GO:0005737; GO:0008017; GO:0014069; GO:0030165; GO:0030425; GO:0031122; GO:0035372; GO:0043025; GO:0043197; GO:0043198; GO:0044877; GO:0045184; GO:0097110; GO:0098978; GO:0099092; GO:0099151; GO:1902897 11515 XM_044328320.1 146 144 115 357 220 Q8BGA7 2.92e-37 Integrator complex subunit 15 Mus musculus (Mouse) NA GO:0032039 11516 XM_044321846.1 1402 700 892 767 1273 Q24799 1.79e-33 Myophilin Echinococcus granulosus (Hydatid tapeworm) NA NA 11517 XM_029354365.2 5 18 18 76 16 NA NA NA NA NA NA 11518 XM_044309265.1 4 0 0 0 67 NA NA NA NA NA NA 11519 XM_029354399.2 77 15 36 57 104 P10394 3.32e-60 Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 11520 XM_029341959.2 2075 1431 1070 2522 2368 Q5U3Q6 2.3e-86 Cdc42-interacting protein 4 homolog (Thyroid receptor-interacting protein 10 homolog) Danio rerio (Zebrafish) (Brachydanio rerio) endocytosis [GO:0006897]; signal transduction [GO:0007165] GO:0005764; GO:0005856; GO:0005886; GO:0005938; GO:0006897; GO:0007165; GO:0008289 11521 XM_044315299.1 56 17 27 52 38 NA NA NA NA NA NA 11522 XM_029330527.2 0 0 194 23 0 NA NA NA NA NA NA 11523 XM_029329626.2 4 0 0 34 0 NA NA NA NA NA NA 11524 XM_044325897.1 83 142 68 59 81 P39087 6.49e-85 Glutamate receptor ionotropic, kainate 2 (GluK2) (Glutamate receptor 6) (GluR-6) (GluR6) (Glutamate receptor beta-2) (GluR beta-2) Mus musculus (Mouse) behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; detection of cold stimulus involved in thermoception [GO:0120169]; excitatory postsynaptic potential [GO:0060079]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; modulation of excitatory postsynaptic potential [GO:0098815]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of membrane potential [GO:0042391]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249] GO:0000149; GO:0001662; GO:0004970; GO:0005234; GO:0005886; GO:0006874; GO:0007268; GO:0008066; GO:0008328; GO:0014069; GO:0015276; GO:0015277; GO:0016020; GO:0019228; GO:0030165; GO:0030424; GO:0030425; GO:0031624; GO:0031625; GO:0032839; GO:0032983; GO:0035249; GO:0038023; GO:0042391; GO:0042734; GO:0042802; GO:0043025; GO:0043113; GO:0043195; GO:0043204; GO:0043524; GO:0043525; GO:0045202; GO:0045211; GO:0046328; GO:0048169; GO:0048172; GO:0050804; GO:0050806; GO:0051402; GO:0051967; GO:0060079; GO:0060080; GO:0097110; GO:0097471; GO:0098686; GO:0098815; GO:0098978; GO:0099171; GO:0099507; GO:0120169; GO:1904315 11525 XM_044312090.1 16 0 0 24 0 Q99MW1 6.15e-30 Serine/threonine-protein kinase 31 (EC 2.7.11.1) Mus musculus (Mouse) protein phosphorylation [GO:0006468] GO:0001669; GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0006468; GO:0106310 11526 XM_029326326.2 7 19 0 21 10 Q9QZ85 7.38e-45 Interferon-inducible GTPase 1 (EC 3.6.5.-) Mus musculus (Mouse) cellular response to interferon-beta [GO:0035458]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; regulation of autophagy [GO:0010506]; response to bacterium [GO:0009617] GO:0003924; GO:0005525; GO:0005737; GO:0005789; GO:0006952; GO:0009617; GO:0010506; GO:0019003; GO:0019221; GO:0020005; GO:0031965; GO:0032580; GO:0035458; GO:0042802; GO:0042832; GO:0045087; GO:0050829 11527 XM_029329558.2 3 3 5 3 10 NA NA NA NA NA NA 11528 XM_044318552.1 0 0 0 0 6 Q15527 8.15e-29 Surfeit locus protein 2 (Surf-2) Homo sapiens (Human) NA GO:0005654; GO:0005730; GO:0005886; GO:0016607 11529 XM_044321908.1 695 594 647 985 694 Q9TZM3 6.99e-130 Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1) (Leucine-rich repeats, ras-like domain, kinase protein 1) (PARK8-related kinase) Caenorhabditis elegans axon extension involved in axon guidance [GO:0048846]; negative regulation of neuron death [GO:1901215]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; response to endoplasmic reticulum stress [GO:0034976]; response to oxidative stress [GO:0006979]; synaptic vesicle transport [GO:0048489] GO:0004674; GO:0005524; GO:0005525; GO:0005737; GO:0005794; GO:0006468; GO:0006979; GO:0008104; GO:0034976; GO:0043025; GO:0046872; GO:0048489; GO:0048846; GO:0106310; GO:1901215 11530 XM_044321908.1 695 594 647 985 694 Q9TZM3 2.29e-78 Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1) (Leucine-rich repeats, ras-like domain, kinase protein 1) (PARK8-related kinase) Caenorhabditis elegans axon extension involved in axon guidance [GO:0048846]; negative regulation of neuron death [GO:1901215]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; response to endoplasmic reticulum stress [GO:0034976]; response to oxidative stress [GO:0006979]; synaptic vesicle transport [GO:0048489] GO:0004674; GO:0005524; GO:0005525; GO:0005737; GO:0005794; GO:0006468; GO:0006979; GO:0008104; GO:0034976; GO:0043025; GO:0046872; GO:0048489; GO:0048846; GO:0106310; GO:1901215 11531 XM_029324873.2 123 53 57 103 142 NA NA NA NA NA NA 11532 XR_006393203.1 117 405 340 171 250 P55006 4.43e-75 Retinol dehydrogenase 7 (EC 1.1.1.105) (Retinol dehydrogenase 3) (Retinol dehydrogenase type III) (RODH III) Rattus norvegicus (Rat) retinol metabolic process [GO:0042572]; steroid metabolic process [GO:0008202] GO:0004745; GO:0005783; GO:0008202; GO:0016491; GO:0042572; GO:0043231 11533 XM_029354193.2 2 18 1 8 0 NA NA NA NA NA NA 11534 XR_006392141.1 0 2 10 0 14 NA NA NA NA NA NA 11535 XM_029337869.2 201 10 0 0 0 Q5FWR0 0 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.4.12) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) DNA double-strand break processing [GO:0000729] GO:0000729; GO:0003677; GO:0004386; GO:0005524; GO:0005634; GO:0016887; GO:0035861; GO:0043130; GO:0140658 11536 XR_006393745.1 79 51 66 10 79 NA NA NA NA NA NA 11537 XR_003827011.2 0 0 0 0 9 NA NA NA NA NA NA 11538 XM_044312365.1 71 57 29 34 6 NA NA NA NA NA NA 11539 XM_029345111.2 0 30 0 24 0 A2RRT9 1.15e-151 Cytochrome P450 4V2 (Docosahexaenoic acid omega-hydroxylase CYP4V2) (EC 1.14.14.79) (Long-chain fatty acid omega-monooxygenase) (EC 1.14.14.80) Rattus norvegicus (Rat) fatty acid omega-oxidation [GO:0010430] GO:0005506; GO:0005789; GO:0010430; GO:0020037; GO:0102033 11540 XR_006393687.1 69 109 31 380 239 NA NA NA NA NA NA 11541 XR_003822943.2 609 385 259 454 69 NA NA NA NA NA NA 11542 XM_029346690.2 772 0 250 170 393 A2AUY4 3.5e-99 Bromodomain adjacent to zinc finger domain protein 2B Mus musculus (Mouse) NA GO:0003677; GO:0005634; GO:0046872 11543 XM_029346690.2 772 0 250 170 393 A2AUY4 2e-59 Bromodomain adjacent to zinc finger domain protein 2B Mus musculus (Mouse) NA GO:0003677; GO:0005634; GO:0046872 11544 XR_006395098.1 39 6 6 47 46 NA NA NA NA NA NA 11545 XM_044323295.1 78 98 46 32 35 E9QAG8 2.62e-75 Zinc finger protein 431 (Zinc finger protein 932) Mus musculus (Mouse) cell differentiation [GO:0030154]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000978; GO:0000981; GO:0003682; GO:0005634; GO:0006357; GO:0030154; GO:0042826; GO:0043433; GO:0045668; GO:0046872 11546 XM_044323295.1 78 98 46 32 35 E9QAG8 4.48e-73 Zinc finger protein 431 (Zinc finger protein 932) Mus musculus (Mouse) cell differentiation [GO:0030154]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000978; GO:0000981; GO:0003682; GO:0005634; GO:0006357; GO:0030154; GO:0042826; GO:0043433; GO:0045668; GO:0046872 11547 XM_044323295.1 78 98 46 32 35 E9QAG8 2.02e-69 Zinc finger protein 431 (Zinc finger protein 932) Mus musculus (Mouse) cell differentiation [GO:0030154]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000978; GO:0000981; GO:0003682; GO:0005634; GO:0006357; GO:0030154; GO:0042826; GO:0043433; GO:0045668; GO:0046872 11548 XM_044323295.1 78 98 46 32 35 E9QAG8 3.5e-69 Zinc finger protein 431 (Zinc finger protein 932) Mus musculus (Mouse) cell differentiation [GO:0030154]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000978; GO:0000981; GO:0003682; GO:0005634; GO:0006357; GO:0030154; GO:0042826; GO:0043433; GO:0045668; GO:0046872 11549 XM_044323295.1 78 98 46 32 35 E9QAG8 1.73e-67 Zinc finger protein 431 (Zinc finger protein 932) Mus musculus (Mouse) cell differentiation [GO:0030154]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000978; GO:0000981; GO:0003682; GO:0005634; GO:0006357; GO:0030154; GO:0042826; GO:0043433; GO:0045668; GO:0046872 11550 XM_044323295.1 78 98 46 32 35 E9QAG8 1.84e-50 Zinc finger protein 431 (Zinc finger protein 932) Mus musculus (Mouse) cell differentiation [GO:0030154]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000978; GO:0000981; GO:0003682; GO:0005634; GO:0006357; GO:0030154; GO:0042826; GO:0043433; GO:0045668; GO:0046872 11551 XM_044328472.1 193 77 80 52 10 Q8R0H9 7.17e-88 ADP-ribosylation factor-binding protein GGA1 (Gamma-adaptin-related protein 1) (Golgi-localized, gamma ear-containing, ARF-binding protein 1) Mus musculus (Mouse) Golgi to plasma membrane protein transport [GO:0043001]; Golgi to plasma membrane transport [GO:0006893]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein catabolic process [GO:0030163]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998] GO:0005654; GO:0005769; GO:0005794; GO:0005802; GO:0005829; GO:0006886; GO:0006893; GO:0008104; GO:0030163; GO:0031267; GO:0031901; GO:0032991; GO:0034394; GO:0035091; GO:0042147; GO:0043001; GO:0043130; GO:0043231; GO:0045732; GO:1901998; GO:1903441 11552 XM_044328472.1 193 77 80 52 10 Q8R0H9 9.13e-33 ADP-ribosylation factor-binding protein GGA1 (Gamma-adaptin-related protein 1) (Golgi-localized, gamma ear-containing, ARF-binding protein 1) Mus musculus (Mouse) Golgi to plasma membrane protein transport [GO:0043001]; Golgi to plasma membrane transport [GO:0006893]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein catabolic process [GO:0030163]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998] GO:0005654; GO:0005769; GO:0005794; GO:0005802; GO:0005829; GO:0006886; GO:0006893; GO:0008104; GO:0030163; GO:0031267; GO:0031901; GO:0032991; GO:0034394; GO:0035091; GO:0042147; GO:0043001; GO:0043130; GO:0043231; GO:0045732; GO:1901998; GO:1903441 11553 XM_044321389.1 146 0 11 64 65 B8VIU6 8.55e-48 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 11554 XM_044313209.1 118 0 29 0 72 Q90511 6.2e-117 Translation initiation factor eIF-2B subunit beta (S20I15) (eIF-2B GDP-GTP exchange factor subunit beta) Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) central nervous system development [GO:0007417]; myelination [GO:0042552]; oligodendrocyte development [GO:0014003]; T cell receptor signaling pathway [GO:0050852]; translational initiation [GO:0006413] GO:0003743; GO:0005524; GO:0005525; GO:0005737; GO:0005851; GO:0006413; GO:0007417; GO:0014003; GO:0042552; GO:0050852 11555 XM_044313189.1 10 0 0 4 11 NA NA NA NA NA NA 11556 XM_029344287.2 1475 835 669 1074 1056 P51688 0 N-sulphoglucosamine sulphohydrolase (EC 3.10.1.1) (Sulfoglucosamine sulfamidase) (Sulphamidase) Homo sapiens (Human) glycosaminoglycan catabolic process [GO:0006027]; heparan sulfate proteoglycan catabolic process [GO:0030200] GO:0005539; GO:0005764; GO:0006027; GO:0008484; GO:0016250; GO:0030200; GO:0043202; GO:0046872; GO:0070062 11557 XM_044312686.1 0 0 0 72 0 NA NA NA NA NA NA 11558 XM_044320363.1 155 108 159 304 489 NA NA NA NA NA NA 11559 XM_044313909.1 0 14 0 0 0 NA NA NA NA NA NA 11560 XM_029347525.2 167 149 35 160 134 NA NA NA NA NA NA 11561 XM_029348725.2 123 68 75 128 200 NA NA NA NA NA NA 11562 XM_029352754.2 687 333 311 774 68 NA NA NA NA NA NA 11563 XM_029330706.2 65 190 161 154 193 P28347 5.12e-38 Transcriptional enhancer factor TEF-1 (NTEF-1) (Protein GT-IIC) (TEA domain family member 1) (TEAD-1) (Transcription factor 13) (TCF-13) Homo sapiens (Human) embryonic organ development [GO:0048568]; hippo signaling [GO:0035329]; positive regulation of cell growth [GO:0030307]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein-containing complex assembly [GO:0065003]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000785; GO:0000978; GO:0000981; GO:0003677; GO:0003700; GO:0005634; GO:0005654; GO:0005667; GO:0006357; GO:0030307; GO:0035329; GO:0045893; GO:0045944; GO:0048568; GO:0065003; GO:0140552; GO:1902895; GO:1990837 11564 XR_006395095.1 0 0 0 11 12 NA NA NA NA NA NA 11565 XM_029342972.2 1185 687 519 1686 1470 NA NA NA NA NA NA 11566 XR_003824529.2 82 32 6 14 73 NA NA NA NA NA NA 11567 XM_044309584.1 1 2 2 1 59 NA NA NA NA NA NA 11568 XR_006394827.1 269 231 112 193 260 NA NA NA NA NA NA 11569 XM_044313453.1 14 0 2 8 6 NA NA NA NA NA NA 11570 XM_029332049.2 0 69 0 0 0 Q8JIR0 1.5e-55 Polycomb complex protein BMI-1-A (Polycomb group RING finger protein 4-A) Danio rerio (Zebrafish) (Brachydanio rerio) cerebellum development [GO:0021549]; hematopoietic stem cell migration [GO:0035701]; histone H2A-K119 monoubiquitination [GO:0036353]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of transcription by RNA polymerase II [GO:0000122]; primitive hemopoiesis [GO:0060215] GO:0000122; GO:0021549; GO:0031519; GO:0035102; GO:0035701; GO:0036353; GO:0045814; GO:0046872; GO:0060215; GO:1990841 11571 XR_006396310.1 1459 1035 712 1228 1354 NA NA NA NA NA NA 11572 XM_029339988.2 419 209 187 227 266 Q8IZF0 0 Sodium leak channel NALCN (CanIon) (Sodium leak channel non-selective protein) (Voltage gated channel-like protein 1) Homo sapiens (Human) calcium ion transmembrane transport [GO:0070588]; ion transmembrane transport [GO:0034220]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; potassium ion transmembrane transport [GO:0071805]; regulation of ion transmembrane transport [GO:0034765]; regulation of resting membrane potential [GO:0060075]; sodium ion transmembrane transport [GO:0035725] GO:0005244; GO:0005248; GO:0005261; GO:0005272; GO:0005886; GO:0022840; GO:0032224; GO:0032230; GO:0034220; GO:0034765; GO:0035725; GO:0060075; GO:0070588; GO:0071805 11573 XM_044308278.1 42 25 11 14 86 NA NA NA NA NA NA 11574 XM_044309799.1 912 1098 579 1312 2312 NA NA NA NA NA NA 11575 XM_044328316.1 860 362 366 471 671 Q9Y383 9.82e-85 Putative RNA-binding protein Luc7-like 2 Homo sapiens (Human) mRNA splice site selection [GO:0006376] GO:0003723; GO:0003729; GO:0005685; GO:0006376; GO:0016607; GO:0019899; GO:0071004 11576 XM_029332415.2 403 423 276 489 762 O88576 1.88e-168 Sodium-dependent neutral amino acid transporter B(0)AT3 (Sodium- and chloride-dependent transporter XTRP2) (Solute carrier family 6 member 18) (System B(0) neutral amino acid transporter AT3) Mus musculus (Mouse) amino acid transmembrane transport [GO:0003333]; neurotransmitter transport [GO:0006836]; neutral amino acid transport [GO:0015804]; renal amino acid absorption [GO:1990297]; sodium ion transmembrane transport [GO:0035725] GO:0003333; GO:0005886; GO:0006836; GO:0015175; GO:0015804; GO:0016324; GO:0031526; GO:0035725; GO:0140931; GO:1990297 11577 XM_029348754.2 100 178 124 163 18 Q5SX19 6.42e-48 N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase (EC 3.5.1.89) (Phosphatidylinositol-glycan biosynthesis class L protein) (PIG-L) Mus musculus (Mouse) GPI anchor biosynthetic process [GO:0006506] GO:0000225; GO:0005783; GO:0005789; GO:0006506; GO:0016811 11578 XM_029348754.2 100 178 124 163 18 Q5SX19 6.42e-48 N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase (EC 3.5.1.89) (Phosphatidylinositol-glycan biosynthesis class L protein) (PIG-L) Mus musculus (Mouse) GPI anchor biosynthetic process [GO:0006506] GO:0000225; GO:0005783; GO:0005789; GO:0006506; GO:0016811 11579 XM_029328559.2 8636 8583 5218 8088 6306 F1MM41 1.74e-41 E3 ubiquitin-protein ligase ZNRF1 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase ZNRF1) (Zinc/RING finger protein 1) Bos taurus (Bovine) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K48-linked ubiquitination [GO:0070936] GO:0004842; GO:0005737; GO:0005764; GO:0005768; GO:0016020; GO:0030672; GO:0043161; GO:0043231; GO:0046872; GO:0061630; GO:0070936 11580 XM_044320326.1 28 0 13 0 102 NA NA NA NA NA NA 11581 XM_029339418.2 286 126 127 238 289 A7S641 0 Protein ST7 homolog Nematostella vectensis (Starlet sea anemone) NA GO:0016020 11582 XM_044325285.1 697 334 326 164 325 Q9UKV8 0 Protein argonaute-2 (Argonaute2) (hAgo2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (PAZ Piwi domain protein) (PPD) (Protein slicer) Homo sapiens (Human) miRNA metabolic process [GO:0010586]; miRNA processing [GO:0035196]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; miRNA-mediated gene silencing by mRNA destabilization [GO:0035279]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; negative regulation of translational initiation [GO:0045947]; positive regulation of angiogenesis [GO:0045766]; positive regulation of gene expression [GO:0010628]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of trophoblast cell migration [GO:1901165]; post-embryonic development [GO:0009791]; pre-miRNA processing [GO:0031054]; RISC complex assembly [GO:0070922]; RNA secondary structure unwinding [GO:0010501]; RNA-mediated gene silencing [GO:0031047]; RNA-mediated post-transcriptional gene silencing [GO:0035194]; siRNA processing [GO:0030422]; siRNA-mediated gene silencing by mRNA destabilization [GO:0090625]; translation [GO:0006412] GO:0000340; GO:0000932; GO:0000993; GO:0001046; GO:0003723; GO:0003725; GO:0003727; GO:0003743; GO:0004521; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005844; GO:0005845; GO:0006412; GO:0008022; GO:0009791; GO:0010501; GO:0010586; GO:0010628; GO:0016020; GO:0016442; GO:0030422; GO:0030425; GO:0031047; GO:0031054; GO:0035194; GO:0035196; GO:0035197; GO:0035198; GO:0035278; GO:0035279; GO:0036464; GO:0042985; GO:0045766; GO:0045944; GO:0045947; GO:0046872; GO:0060213; GO:0070062; GO:0070551; GO:0070578; GO:0070922; GO:0090624; GO:0090625; GO:0098808; GO:1900153; GO:1901165; GO:1990904 11583 XR_006397732.1 1 3 0 0 6 NA NA NA NA NA NA 11584 XM_044324678.1 44 68 68 115 183 NA NA NA NA NA NA 11585 XR_003823242.2 0 76 0 0 27 NA NA NA NA NA NA 11586 XM_044328445.1 14 0 174 619 22 NA NA NA NA NA NA 11587 XM_044315542.1 47 15 67 35 235 NA NA NA NA NA NA 11588 XR_003824401.2 168 398 256 717 498 NA NA NA NA NA NA 11589 XM_044313433.1 0 0 18 5 31 NA NA NA NA NA NA 11590 XM_029336728.2 1839 1413 971 2201 1358 P07942 2.48e-114 Laminin subunit beta-1 (Laminin B1 chain) (Laminin-1 subunit beta) (Laminin-10 subunit beta) (Laminin-12 subunit beta) (Laminin-2 subunit beta) (Laminin-6 subunit beta) (Laminin-8 subunit beta) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; basement membrane assembly [GO:0070831]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; endodermal cell differentiation [GO:0035987]; neuron projection development [GO:0031175]; neuronal-glial interaction involved in cerebral cortex radial glia guided migration [GO:0021812]; odontogenesis [GO:0042476]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of muscle cell differentiation [GO:0051149]; regulation of basement membrane organization [GO:0110011]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888] GO:0005178; GO:0005198; GO:0005201; GO:0005576; GO:0005604; GO:0005606; GO:0005607; GO:0005615; GO:0005788; GO:0007155; GO:0009887; GO:0009888; GO:0016477; GO:0021812; GO:0030335; GO:0031175; GO:0034446; GO:0035987; GO:0042476; GO:0043256; GO:0043257; GO:0043259; GO:0045785; GO:0048471; GO:0050679; GO:0051149; GO:0062023; GO:0070062; GO:0070831; GO:0098637; GO:0110011; GO:2001046 11591 XM_029336728.2 1839 1413 971 2201 1358 P07942 1.65e-22 Laminin subunit beta-1 (Laminin B1 chain) (Laminin-1 subunit beta) (Laminin-10 subunit beta) (Laminin-12 subunit beta) (Laminin-2 subunit beta) (Laminin-6 subunit beta) (Laminin-8 subunit beta) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; basement membrane assembly [GO:0070831]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; endodermal cell differentiation [GO:0035987]; neuron projection development [GO:0031175]; neuronal-glial interaction involved in cerebral cortex radial glia guided migration [GO:0021812]; odontogenesis [GO:0042476]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of muscle cell differentiation [GO:0051149]; regulation of basement membrane organization [GO:0110011]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888] GO:0005178; GO:0005198; GO:0005201; GO:0005576; GO:0005604; GO:0005606; GO:0005607; GO:0005615; GO:0005788; GO:0007155; GO:0009887; GO:0009888; GO:0016477; GO:0021812; GO:0030335; GO:0031175; GO:0034446; GO:0035987; GO:0042476; GO:0043256; GO:0043257; GO:0043259; GO:0045785; GO:0048471; GO:0050679; GO:0051149; GO:0062023; GO:0070062; GO:0070831; GO:0098637; GO:0110011; GO:2001046 11592 XM_029332834.2 222 96 180 176 189 Q6GQN8 6.9e-107 Enoyl-[acyl-carrier-protein] reductase, mitochondrial (EC 1.3.1.104) (2-enoyl thioester reductase) Danio rerio (Zebrafish) (Brachydanio rerio) fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631] GO:0005739; GO:0006631; GO:0006633; GO:0019166 11593 XM_029339827.2 4830 3690 3404 4523 3459 G8HTB6 2.19e-38 ZP domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 11594 XM_029334118.2 273 231 114 279 134 NA NA NA NA NA NA 11595 XR_006395041.1 40 0 36 2 88 NA NA NA NA NA NA 11596 XM_044310701.1 353 1001 144 39 91 NA NA NA NA NA NA 11597 XM_029358494.2 186 169 76 116 164 NA NA NA NA NA NA 11598 XM_044308704.1 97 200 37 105 26 NA NA NA NA NA NA 11599 XM_044316428.1 188 38 11 229 135 NA NA NA NA NA NA 11600 XM_044323961.1 8 4 16 0 28 NA NA NA NA NA NA 11601 XR_006395290.1 232 382 329 154 238 NA NA NA NA NA NA 11602 XM_029324891.2 60 59 67 81 196 Q5RGB8 7.35e-39 Kelch-like protein 26 Danio rerio (Zebrafish) (Brachydanio rerio) NA NA 11603 XM_044326882.1 0 30 20 23 56 NA NA NA NA NA NA 11604 XM_029332366.2 1015 437 365 729 599 NA NA NA NA NA NA 11605 XM_044311614.1 55 61 58 39 259 NA NA NA NA NA NA 11606 XR_006392476.1 33 4 34 27 131 NA NA NA NA NA NA 11607 XM_044308900.1 339 41 55 270 371 P35546 9.02e-84 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; anatomical structure morphogenesis [GO:0009653]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006919; GO:0007156; GO:0007158; GO:0007169; GO:0007399; GO:0009410; GO:0009653; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030182; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0098797; GO:2001241 11608 XM_029331307.2 7561 7272 6219 7123 5957 O15488 1.51e-95 Glycogenin-2 (GN-2) (GN2) (EC 2.4.1.186) Homo sapiens (Human) glycogen biosynthetic process [GO:0005978] GO:0005737; GO:0005829; GO:0005978; GO:0008466; GO:0016757; GO:0046872; GO:0102751 11609 XM_044321803.1 6 0 0 8 0 P48040 1.02e-24 Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor) Ovis aries (Sheep) NA GO:0005886; GO:0008502 11610 XM_029352207.2 22 15 20 47 109 Q09575 3.9e-35 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 11611 XR_006393344.1 0 0 2 15 2 NA NA NA NA NA NA 11612 XR_006396573.1 19 18 7 25 29 Q8K0U4 1.86e-119 Heat shock 70 kDa protein 12A Mus musculus (Mouse) NA GO:0005524; GO:0005634; GO:0005737 11613 XR_006394652.1 249 94 153 448 166 Q96AY4 1.11e-45 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11614 XR_006394652.1 249 94 153 448 166 Q96AY4 1.87e-45 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11615 XR_006394652.1 249 94 153 448 166 Q96AY4 3.17e-45 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11616 XR_006394652.1 249 94 153 448 166 Q96AY4 2.84e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11617 XR_006394652.1 249 94 153 448 166 Q96AY4 2.27e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11618 XR_006394652.1 249 94 153 448 166 Q96AY4 2.27e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11619 XR_006394652.1 249 94 153 448 166 Q96AY4 1.73e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11620 XR_006394652.1 249 94 153 448 166 Q96AY4 2.17e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11621 XR_006394652.1 249 94 153 448 166 Q96AY4 1.69e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11622 XR_006394652.1 249 94 153 448 166 Q96AY4 1.69e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11623 XR_006394652.1 249 94 153 448 166 Q96AY4 7.02e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11624 XR_006394652.1 249 94 153 448 166 Q96AY4 7.02e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11625 XR_006394652.1 249 94 153 448 166 Q96AY4 2.16e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11626 XM_029357384.2 149 138 82 215 282 Q1JQC6 1.64e-119 NAD-dependent protein lipoamidase sirtuin-4, mitochondrial (EC 2.3.1.-) (NAD-dependent ADP-ribosyltransferase sirtuin-4) (EC 2.4.2.-) (NAD-dependent protein biotinylase sirtuin-4) (EC 2.3.1.-) (NAD-dependent protein deacetylase sirtuin-4) (EC 2.3.1.286) (Regulatory protein SIR2 homolog 4) (SIR2-like protein 4) Bos taurus (Bovine) cellular response to DNA damage stimulus [GO:0006974]; glutamine metabolic process [GO:0006541]; negative regulation of fatty acid oxidation [GO:0046322]; negative regulation of insulin secretion [GO:0046676]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of lipid biosynthetic process [GO:0046889]; protein deacetylation [GO:0006476]; regulation of pyruvate dehydrogenase activity [GO:1904182]; tricarboxylic acid metabolic process [GO:0072350] GO:0003950; GO:0005739; GO:0005759; GO:0006476; GO:0006541; GO:0006974; GO:0008270; GO:0016779; GO:0019213; GO:0034979; GO:0034983; GO:0046322; GO:0046676; GO:0046889; GO:0070403; GO:0072350; GO:0106419; GO:0106420; GO:0140803; GO:1904182 11627 XM_044325698.1 12 12 4 0 6 NA NA NA NA NA NA 11628 XM_029336796.2 279 146 86 247 172 NA NA NA NA NA NA 11629 XM_044321677.1 2 88 0 18 0 Q8K3Z0 6.31e-35 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 11630 XM_029334461.2 385 206 223 342 439 Q63ZP1 2.08e-101 PHD finger protein 10 Xenopus laevis (African clawed frog) nervous system development [GO:0007399] GO:0007399; GO:0046872; GO:0071564 11631 XM_029342354.2 1203 729 502 658 624 P98156 7.3e-158 Very low-density lipoprotein receptor (VLDL receptor) (VLDL-R) Mus musculus (Mouse) cellular response to hypoxia [GO:0071456]; cholesterol metabolic process [GO:0008203]; dendrite morphogenesis [GO:0048813]; glycoprotein transport [GO:0034436]; lipid transport [GO:0006869]; positive regulation of dendrite development [GO:1900006]; positive regulation of protein kinase activity [GO:0045860]; receptor-mediated endocytosis [GO:0006898]; reelin-mediated signaling pathway [GO:0038026]; ventral spinal cord development [GO:0021517]; very-low-density lipoprotein particle clearance [GO:0034447] GO:0005509; GO:0005615; GO:0005634; GO:0005886; GO:0005905; GO:0006869; GO:0006898; GO:0008203; GO:0009986; GO:0016020; GO:0021517; GO:0030229; GO:0034185; GO:0034189; GO:0034361; GO:0034436; GO:0034447; GO:0038024; GO:0038025; GO:0038026; GO:0043235; GO:0045177; GO:0045860; GO:0048306; GO:0048471; GO:0048813; GO:0071456; GO:1900006 11632 XR_006393121.1 280 112 15 50 28 NA NA NA NA NA NA 11633 XR_006397582.1 22 1 16 0 25 NA NA NA NA NA NA 11634 XM_029325823.2 91 10 11 15 48 NA NA NA NA NA NA 11635 XM_029348077.2 85 140 118 124 182 Q3TBW2 3.37e-28 39S ribosomal protein L10, mitochondrial (L10mt) (MRP-L10) Mus musculus (Mouse) mitochondrial translation [GO:0032543]; translation [GO:0006412] GO:0003735; GO:0005654; GO:0005739; GO:0005743; GO:0005762; GO:0006412; GO:0015934; GO:0032543; GO:1990904 11636 XM_044317172.1 46 0 75 210 115 NA NA NA NA NA NA 11637 XM_029338524.2 13116 10873 5426 6764 5915 Q15370 1.1e-45 Elongin-B (EloB) (Elongin 18 kDa subunit) (RNA polymerase II transcription factor SIII subunit B) (SIII p18) (Transcription elongation factor B polypeptide 2) Homo sapiens (Human) positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein ubiquitination [GO:0016567]; protein-containing complex assembly [GO:0065003]; transcription elongation by RNA polymerase II promoter [GO:0006368]; transcription initiation at RNA polymerase II promoter [GO:0006367] GO:0001222; GO:0005654; GO:0005829; GO:0006367; GO:0006368; GO:0016567; GO:0030891; GO:0031462; GO:0031466; GO:0031625; GO:0032436; GO:0065003; GO:0070449 11638 XM_044325950.1 0 0 0 54 29 NA NA NA NA NA NA 11639 XM_029351006.2 5 0 16 22 0 Q96DM1 6.46e-47 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 11640 XM_029336543.2 4324 3447 1736 3023 2196 O14874 1.26e-133 [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial (EC 2.7.11.4) (Branched-chain alpha-ketoacid dehydrogenase kinase) (BCKD-kinase) (BCKDHKIN) Homo sapiens (Human) amino acid catabolic process [GO:0009063]; branched-chain amino acid catabolic process [GO:0009083]; negative regulation of cellular amino acid metabolic process [GO:0045763]; phosphorylation [GO:0016310]; protein phosphorylation [GO:0006468]; regulation of glucose metabolic process [GO:0010906] GO:0004674; GO:0004740; GO:0005524; GO:0005739; GO:0005759; GO:0005947; GO:0006468; GO:0009063; GO:0009083; GO:0010906; GO:0016301; GO:0016310; GO:0045763; GO:0047323 11641 XM_044319545.1 0 2 17 8 5 NA NA NA NA NA NA 11642 XM_044309313.1 18 1 6 0 3 NA NA NA NA NA NA 11643 XM_029357709.2 1449 1221 727 918 1323 E7FA21 1.3e-34 Guanine nucleotide exchange protein smcr8a (Smith-Magenis syndrome chromosomal region candidate gene 8 protein homolog A) Danio rerio (Zebrafish) (Brachydanio rerio) autophagy [GO:0006914]; regulation of response to stimulus [GO:0048583] GO:0005085; GO:0005096; GO:0005634; GO:0005737; GO:0006914; GO:0032045; GO:0048583 11644 XM_044325684.1 12 6 21 7 47 NA NA NA NA NA NA 11645 XM_044325300.1 23 2 36 78 59 NA NA NA NA NA NA 11646 XM_044322308.1 0 0 0 6 5 Q07497 8.37e-23 Ephrin type-B receptor 5 (EC 2.7.10.1) (EPH-like kinase 9) (EK9) (cEK9) Gallus gallus (Chicken) axon guidance [GO:0007411]; central nervous system projection neuron axonogenesis [GO:0021952]; positive regulation of kinase activity [GO:0033674]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0004714; GO:0005005; GO:0005524; GO:0005886; GO:0007169; GO:0007411; GO:0021952; GO:0033674; GO:0043005; GO:0043235 11647 XM_029327149.2 175 101 1 0 0 P43140 1.09e-28 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) Rattus norvegicus (Rat) activation of phospholipase C activity [GO:0007202]; adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; adrenergic receptor signaling pathway [GO:0071875]; adult heart development [GO:0007512]; aging [GO:0007568]; calcium ion transport into cytosol [GO:0060402]; cell growth involved in cardiac muscle cell development [GO:0061049]; cell-cell signaling [GO:0007267]; MAPK cascade [GO:0000165]; micturition [GO:0060073]; multicellular organism aging [GO:0010259]; negative regulation of autophagy [GO:0010507]; negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure [GO:0001985]; negative regulation of Rho protein signal transduction [GO:0035024]; neuron-glial cell signaling [GO:0150099]; norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001994]; organ growth [GO:0035265]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; pilomotor reflex [GO:0097195]; positive regulation of action potential [GO:0045760]; positive regulation of cardiac muscle contraction [GO:0060452]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of heart rate [GO:0010460]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; positive regulation of systemic arterial blood pressure [GO:0003084]; positive regulation of the force of heart contraction by epinephrine-norepinephrine [GO:0001997]; positive regulation of vasoconstriction [GO:0045907]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of blood pressure [GO:0008217]; response to hormone [GO:0009725]; response to xenobiotic stimulus [GO:0009410] GO:0000165; GO:0001985; GO:0001994; GO:0001996; GO:0001997; GO:0003084; GO:0004930; GO:0004937; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0005901; GO:0007200; GO:0007202; GO:0007204; GO:0007267; GO:0007512; GO:0007568; GO:0008217; GO:0009410; GO:0009725; GO:0010259; GO:0010460; GO:0010507; GO:0010613; GO:0016020; GO:0030018; GO:0030315; GO:0031965; GO:0032230; GO:0035024; GO:0035265; GO:0042734; GO:0043410; GO:0045211; GO:0045760; GO:0045907; GO:0045987; GO:0046982; GO:0060073; GO:0060402; GO:0060452; GO:0061049; GO:0070374; GO:0071875; GO:0071880; GO:0090037; GO:0097195; GO:0098691; GO:0098978; GO:0098982; GO:0099171; GO:0150099; GO:1903997 11648 XM_044315963.1 2 0 19 0 0 B8VIU6 6.54e-48 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 11649 XM_029330598.2 0 18 6 41 39 Q3MV19 5.87e-38 TNF receptor-associated factor 6-A (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6-A) Xenopus laevis (African clawed frog) activation of NF-kappaB-inducing kinase activity [GO:0007250]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122] GO:0004842; GO:0005164; GO:0005634; GO:0005811; GO:0005938; GO:0007250; GO:0008270; GO:0042981; GO:0043122; GO:0070534 11650 XM_044320065.1 78 41 75 59 33 NA NA NA NA NA NA 11651 XR_006391439.1 99 81 131 77 243 NA NA NA NA NA NA 11652 XM_029338911.2 34 124 8 27 71 Q9EQD2 2.37e-21 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 11653 XM_044308950.1 8 0 0 5 0 NA NA NA NA NA NA 11654 XR_006393483.1 0 0 0 5 6 NA NA NA NA NA NA 11655 XM_029340662.2 17 8 8 4 39 Q91822 1.77e-46 Serine/threonine-protein kinase pim-3 (EC 2.7.11.1) (Pim-1) Xenopus laevis (African clawed frog) apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; protein phosphorylation [GO:0006468] GO:0004674; GO:0005524; GO:0005737; GO:0006468; GO:0006915; GO:0043066; GO:0106310 11656 XM_044316756.1 122 112 68 96 102 Q9CR50 2.76e-55 RING finger and CHY zinc finger domain-containing protein 1 (EC 2.3.2.27) (Androgen receptor N-terminal-interacting protein) (CH-rich-interacting match with PLAG1) (E3 ubiquitin-protein ligase Pirh2) (RING-type E3 ubiquitin transferase RCHY1) (Zinc finger protein 363) Mus musculus (Mouse) positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; protein autoubiquitination [GO:0051865]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000151; GO:0002039; GO:0005102; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006511; GO:0008270; GO:0016567; GO:0016607; GO:0031398; GO:0032436; GO:0042803; GO:0043231; GO:0051865; GO:0061630 11657 XM_044317636.1 2295 1547 1033 1810 2764 Q5RHH4 0 Intraflagellar transport protein 172 homolog Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; intraciliary transport [GO:0042073]; photoreceptor cell maintenance [GO:0045494]; pronephros development [GO:0048793]; regulation of TOR signaling [GO:0032006]; retina development in camera-type eye [GO:0060041] GO:0005929; GO:0005930; GO:0030992; GO:0032006; GO:0036064; GO:0042073; GO:0045494; GO:0048793; GO:0060041; GO:0060271 11658 XM_044308100.1 72 60 131 122 120 B0CQN7 3.48e-31 NADH-cytochrome b5 reductase 1 (EC 1.6.2.2) (Microsomal cytochrome b reductase) Laccaria bicolor (strain S238N-H82 / ATCC MYA-4686) (Bicoloured deceiver) (Laccaria laccata var. bicolor) peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]; tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation [GO:0002926] GO:0002926; GO:0003954; GO:0004128; GO:0005741; GO:0016740; GO:0017183 11659 XM_044309304.1 4 0 14 0 10 NA NA NA NA NA NA 11660 XM_044310923.1 119 0 63 12 302 NA NA NA NA NA NA 11661 XM_044319452.1 624 387 569 681 583 NA NA NA NA NA NA 11662 XM_044329187.1 71 13 18 26 15 NA NA NA NA NA NA 11663 XM_029346719.2 10062 11699 4276 7495 2494 NA NA NA NA NA NA 11664 XM_044309956.1 182 104 112 173 145 Q99715 5.81e-47 Collagen alpha-1(XII) chain Homo sapiens (Human) cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; endodermal cell differentiation [GO:0035987] GO:0005576; GO:0005595; GO:0005615; GO:0005788; GO:0007155; GO:0030020; GO:0030199; GO:0035987; GO:0062023; GO:0070062; GO:1903561 11665 XM_044309956.1 182 104 112 173 145 Q99715 1.8e-21 Collagen alpha-1(XII) chain Homo sapiens (Human) cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; endodermal cell differentiation [GO:0035987] GO:0005576; GO:0005595; GO:0005615; GO:0005788; GO:0007155; GO:0030020; GO:0030199; GO:0035987; GO:0062023; GO:0070062; GO:1903561 11666 XM_029341676.2 366 93 118 192 107 NA NA NA NA NA NA 11667 XM_029331434.2 9 0 6 0 75 Q55FK2 6.3e-56 Ras-related protein Rab-6 Dictyostelium discoideum (Social amoeba) intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] GO:0003924; GO:0005525; GO:0005794; GO:0005811; GO:0005829; GO:0006886; GO:0006890; GO:0006891; GO:0012505; GO:0042147; GO:0140220 11668 XM_044323776.1 97 56 54 95 106 Q8N1F8 1.19e-47 Serine/threonine-protein kinase 11-interacting protein (LKB1-interacting protein 1) Homo sapiens (Human) protein localization [GO:0008104] GO:0005576; GO:0005737; GO:0005765; GO:0008104; GO:0019901; GO:0035578; GO:0043231 11669 XM_029325748.2 370 236 201 298 349 Q23915 1.63e-24 Probable serine/threonine-protein kinase kinX (EC 2.7.11.1) Dictyostelium discoideum (Social amoeba) protein phosphorylation [GO:0006468]; signal transduction [GO:0007165] GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0006468; GO:0007165; GO:0106310 11670 XM_044325848.1 32 8 48 16 124 NA NA NA NA NA NA 11671 XM_044310163.1 5 3 0 7 3 NA NA NA NA NA NA 11672 XM_029339159.2 111 96 62 0 760 A4QNE6 3.47e-163 Dynein axonemal assembly factor 10 (WD repeat-containing protein 92) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) apoptotic process [GO:0006915]; axonemal dynein complex assembly [GO:0070286] GO:0006915; GO:0070286; GO:0120293 11673 XM_029343335.2 373 162 27 253 111 NA NA NA NA NA NA 11674 XM_029346740.2 1205 719 589 1466 1330 NA NA NA NA NA NA 11675 XM_029329722.2 4069 3707 1724 4209 2660 Q68F50 1.24e-128 Twinfilin-1 Xenopus laevis (African clawed frog) negative regulation of actin filament polymerization [GO:0030837] GO:0003779; GO:0005737; GO:0005856; GO:0030837 11676 XM_044320561.1 0 0 84 0 0 NA NA NA NA NA NA 11677 XM_044320838.1 36 1 147 99 68 NA NA NA NA NA NA 11678 XR_003827206.2 0 0 29 35 0 NA NA NA NA NA NA 11679 XR_006393416.1 7 7 5 8 22 NA NA NA NA NA NA 11680 XM_044322649.1 4 14 1 10 8 NA NA NA NA NA NA 11681 XM_044319122.1 156 260 190 75 0 NA NA NA NA NA NA 11682 XR_003826466.2 64 0 4 49 2 NA NA NA NA NA NA 11683 XM_029352424.2 51 13 138 57 7 NA NA NA NA NA NA 11684 XM_029346584.2 7954 10918 10712 10732 9394 NA NA NA NA NA NA 11685 XM_029333441.2 0 0 0 27 0 NA NA NA NA NA NA 11686 XR_003827362.1 0 0 10 5 0 NA NA NA NA NA NA 11687 XM_029348167.2 0 9 9 27 0 Q6NW96 1.86e-79 Transcription factor Sp9 Danio rerio (Zebrafish) (Brachydanio rerio) embryonic limb morphogenesis [GO:0030326]; embryonic pectoral fin morphogenesis [GO:0035118]; positive regulation of fibroblast growth factor receptor signaling pathway [GO:0045743]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0030326; GO:0035118; GO:0045743; GO:0046872 11688 XM_029357178.2 565 524 344 468 282 Q9U6D3 1.41e-29 Calmodulin (CaM) Myxine glutinosa (Atlantic hagfish) NA GO:0005509 11689 XM_044309938.1 13 31 21 31 110 Q15485 2.69e-79 Ficolin-2 (37 kDa elastin-binding protein) (Collagen/fibrinogen domain-containing protein 2) (EBP-37) (Ficolin-B) (Ficolin-beta) (Hucolin) (L-ficolin) (Serum lectin p35) Homo sapiens (Human) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; positive regulation of opsonization [GO:1903028]; proteolysis [GO:0006508]; recognition of apoptotic cell [GO:0043654] GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005576; GO:0005581; GO:0005615; GO:0006508; GO:0008228; GO:0009897; GO:0042802; GO:0043394; GO:0043654; GO:0046872; GO:0048306; GO:0050829; GO:0050830; GO:0062023; GO:0070062; GO:0072562; GO:0097367; GO:1903028; GO:1905370; GO:2001065 11690 XM_044316054.1 215 81 97 3 1 NA NA NA NA NA NA 11691 XM_029337230.2 159 213 146 208 158 NA NA NA NA NA NA 11692 XM_029339810.2 34 24 50 30 17 Q4UMH6 4.7e-26 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 11693 XM_044308302.1 1944 2476 879 1246 1604 Q9EQJ0 1.07e-161 Two pore calcium channel protein 1 (Voltage-dependent calcium channel protein TPC1) Mus musculus (Mouse) endocytosis involved in viral entry into host cell [GO:0075509]; positive regulation of autophagy [GO:0010508]; regulation of ion transmembrane transport [GO:0034765]; sodium ion transmembrane transport [GO:0035725] GO:0005244; GO:0005248; GO:0005765; GO:0010008; GO:0010508; GO:0015280; GO:0016020; GO:0019905; GO:0031901; GO:0034765; GO:0035725; GO:0036019; GO:0042802; GO:0042803; GO:0055038; GO:0072345; GO:0075509; GO:0080025; GO:0097682 11694 XM_029351618.2 8 0 15 1 15 NA NA NA NA NA NA 11695 XM_029358026.2 208 191 243 173 94 P41164 5.67e-61 ETS translocation variant 1 (Ets-related protein 81) Mus musculus (Mouse) axon guidance [GO:0007411]; cell differentiation [GO:0030154]; mechanosensory behavior [GO:0007638]; muscle organ development [GO:0007517]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0001228; GO:0003700; GO:0005634; GO:0006357; GO:0007411; GO:0007517; GO:0007638; GO:0030154; GO:0045893; GO:0045944; GO:1990837 11696 XM_044327944.1 140 72 45 60 144 NA NA NA NA NA NA 11697 XR_003827170.2 0 0 11 0 6 Q4KM95 2.2e-42 Leucine-rich repeat-containing protein 42 Rattus norvegicus (Rat) NA NA 11698 XM_044316679.1 679 258 344 498 337 NA NA NA NA NA NA 11699 XM_029344257.2 121 215 100 216 255 NA NA NA NA NA NA 11700 XM_029334938.2 643 258 404 1068 677 A2AAY5 1.06e-34 SH3 and PX domain-containing protein 2B (Factor for adipocyte differentiation 49) (Tyrosine kinase substrate with four SH3 domains) Mus musculus (Mouse) adipose tissue development [GO:0060612]; bone development [GO:0060348]; cranial skeletal system development [GO:1904888]; extracellular matrix disassembly [GO:0022617]; eye development [GO:0001654]; heart development [GO:0007507]; osteoblast fate commitment [GO:0002051]; podosome assembly [GO:0071800]; positive regulation of adipose tissue development [GO:1904179]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of gene expression [GO:0010628]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of stress fiber assembly [GO:0051496]; protein localization to membrane [GO:0072657]; regulation of brood size [GO:0060378]; skeletal system development [GO:0001501]; skeletal system morphogenesis [GO:0048705]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801] GO:0001501; GO:0001654; GO:0002051; GO:0002102; GO:0005737; GO:0006801; GO:0007507; GO:0010314; GO:0010628; GO:0016176; GO:0022617; GO:0032266; GO:0040018; GO:0042169; GO:0042554; GO:0042995; GO:0045600; GO:0048705; GO:0051496; GO:0060348; GO:0060378; GO:0060612; GO:0070161; GO:0070273; GO:0071800; GO:0072657; GO:0080025; GO:1904179; GO:1904888 11701 XM_044324465.1 1996 0 0 392 582 NA NA NA NA NA NA 11702 XM_029335517.2 725 1477 284 948 305 Q07E02 6.86e-51 Caveolin-1 Ornithorhynchus anatinus (Duckbill platypus) caveola assembly [GO:0070836]; cell differentiation [GO:0030154]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of protein tyrosine kinase activity [GO:0061099]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; receptor internalization [GO:0031623]; regulation of cytosolic calcium ion concentration [GO:0051480]; T cell costimulation [GO:0031295] GO:0000139; GO:0001937; GO:0005768; GO:0005794; GO:0005886; GO:0005901; GO:0019901; GO:0030154; GO:0030512; GO:0031295; GO:0031410; GO:0031623; GO:0044325; GO:0045121; GO:0048471; GO:0051480; GO:0060090; GO:0061099; GO:0070836 11703 XR_003825390.2 343 362 358 613 902 NA NA NA NA NA NA 11704 XR_006393124.1 9 0 14 0 54 NA NA NA NA NA NA 11705 XM_044325560.1 33 0 0 9 25 NA NA NA NA NA NA 11706 XR_003825208.2 428 673 432 452 1244 NA NA NA NA NA NA 11707 XR_006394886.1 0 0 7 0 21 NA NA NA NA NA NA 11708 XM_044326702.1 184 117 13 62 46 NA NA NA NA NA NA 11709 XM_029327433.2 364 368 341 543 569 Q96IR7 2.1e-56 4-hydroxyphenylpyruvate dioxygenase-like protein (HPD-like protein) (EC 1.13.-.-) (Glyoxalase domain-containing protein 1) Homo sapiens (Human) aromatic amino acid metabolic process [GO:0009072] GO:0003868; GO:0005739; GO:0009072; GO:0046872 11710 XM_029345149.2 43 85 53 97 179 O54799 4.12e-24 Neuromedin-B receptor (NMB-R) (Neuromedin-B-preferring bombesin receptor) Mus musculus (Mouse) antiviral innate immune response [GO:0140374]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of interleukin-6 production [GO:0032715]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of osteoclast proliferation [GO:0090290]; positive regulation of respiratory gaseous exchange [GO:1903942]; sneeze reflex [GO:0160023] GO:0004930; GO:0004946; GO:0005829; GO:0005886; GO:0007186; GO:0008188; GO:0032715; GO:0032727; GO:0090290; GO:0140374; GO:0160023; GO:1903942 11711 XM_044310427.1 0 3 0 63 0 NA NA NA NA NA NA 11712 XM_029324147.2 8501 9297 5317 8914 9368 Q6NYB7 2.01e-124 Ras-related protein Rab-1A (EC 3.6.5.2) Rattus norvegicus (Rat) autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; cell migration [GO:0016477]; COPII-coated vesicle cargo loading [GO:0090110]; defense response to bacterium [GO:0042742]; endocytosis [GO:0006897]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; growth hormone secretion [GO:0030252]; intracellular protein transport [GO:0006886]; melanosome transport [GO:0032402]; positive regulation of glycoprotein metabolic process [GO:1903020]; positive regulation of interleukin-8 production [GO:0032757]; Rab protein signal transduction [GO:0032482]; substrate adhesion-dependent cell spreading [GO:0034446]; vesicle transport along microtubule [GO:0047496]; virion assembly [GO:0019068] GO:0000045; GO:0000139; GO:0003924; GO:0003925; GO:0005525; GO:0005769; GO:0005789; GO:0005794; GO:0005829; GO:0006886; GO:0006888; GO:0006897; GO:0006914; GO:0007030; GO:0012505; GO:0016477; GO:0019068; GO:0030252; GO:0032402; GO:0032482; GO:0032757; GO:0034446; GO:0042470; GO:0042742; GO:0043025; GO:0047496; GO:0090110; GO:0098793; GO:1903020 11713 XM_029343048.2 1 7 3 0 2 P22843 1.27e-47 Histone H3 Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 11714 XM_029327410.2 48 0 0 0 0 NA NA NA NA NA NA 11715 XM_044321772.1 0 31 0 1 0 NA NA NA NA NA NA 11716 XM_029327003.2 679 644 333 624 593 Q5E9B3 1.11e-169 Geranylgeranyl transferase type-2 subunit beta (EC 2.5.1.60) (Geranylgeranyl transferase type II subunit beta) (GGTase-II-beta) (Rab geranyl-geranyltransferase subunit beta) (Rab GG transferase beta) (Rab GGTase beta) (Rab geranylgeranyltransferase subunit beta) (Type II protein geranyl-geranyltransferase subunit beta) Bos taurus (Bovine) protein geranylgeranylation [GO:0018344]; protein prenylation [GO:0018342] GO:0004663; GO:0005968; GO:0008270; GO:0018342; GO:0018344; GO:0031267 11717 XM_029353934.2 49 0 0 0 0 D3Z5L6 3.16e-59 MFS-type transporter SLC18B1 (Solute carrier family 18 member B1) (Vesicular polyamine transporter) (VPAT) Mus musculus (Mouse) serotonin transport [GO:0006837]; serotonin uptake [GO:0051610]; spermidine transport [GO:0015848]; spermine transport [GO:0000296] GO:0000296; GO:0006837; GO:0015311; GO:0015312; GO:0015848; GO:0022857; GO:0030667; GO:0030672; GO:0051610 11718 XM_029334727.2 0 0 276 1 1525 Q01887 1.12e-113 Tyrosine-protein kinase RYK (EC 2.7.10.1) (Kinase VIK) (Met-related kinase) (NYK-R) Mus musculus (Mouse) axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cell proliferation in midbrain [GO:0033278]; chemorepulsion of axon [GO:0061643]; chemorepulsion of dopaminergic neuron axon [GO:0036518]; commissural neuron axon guidance [GO:0071679]; corpus callosum development [GO:0022038]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative chemotaxis [GO:0050919]; negative regulation of axon extension involved in axon guidance [GO:0048843]; neuron differentiation [GO:0030182]; neuron projection development [GO:0031175]; planar cell polarity pathway involved in axon guidance [GO:1904938]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; protein phosphorylation [GO:0006468]; skeletal system morphogenesis [GO:0048705]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953] GO:0004672; GO:0004888; GO:0005109; GO:0005524; GO:0005634; GO:0005737; GO:0005886; GO:0006468; GO:0007169; GO:0007409; GO:0007411; GO:0016020; GO:0016055; GO:0017147; GO:0022038; GO:0030182; GO:0031175; GO:0033278; GO:0033674; GO:0036518; GO:0042813; GO:0043235; GO:0043410; GO:0048705; GO:0048843; GO:0048846; GO:0050919; GO:0061643; GO:0071679; GO:1904938; GO:1904948; GO:1904953 11719 XM_029349706.2 1185 731 787 1267 1224 Q9ESE1 0 Lipopolysaccharide-responsive and beige-like anchor protein (Beige-like protein) Mus musculus (Mouse) cellular response to leukemia inhibitory factor [GO:1990830]; endosomal transport [GO:0016197]; mitophagy [GO:0000423]; protein localization [GO:0008104]; protein localization to phagophore assembly site [GO:0034497]; signal transduction [GO:0007165] GO:0000423; GO:0005764; GO:0005765; GO:0005783; GO:0005789; GO:0005802; GO:0005829; GO:0005886; GO:0007165; GO:0008104; GO:0016020; GO:0016197; GO:0019901; GO:0031410; GO:0034497; GO:0051018; GO:1990830 11720 XM_029349706.2 1185 731 787 1267 1224 Q9ESE1 0 Lipopolysaccharide-responsive and beige-like anchor protein (Beige-like protein) Mus musculus (Mouse) cellular response to leukemia inhibitory factor [GO:1990830]; endosomal transport [GO:0016197]; mitophagy [GO:0000423]; protein localization [GO:0008104]; protein localization to phagophore assembly site [GO:0034497]; signal transduction [GO:0007165] GO:0000423; GO:0005764; GO:0005765; GO:0005783; GO:0005789; GO:0005802; GO:0005829; GO:0005886; GO:0007165; GO:0008104; GO:0016020; GO:0016197; GO:0019901; GO:0031410; GO:0034497; GO:0051018; GO:1990830 11721 XM_029349706.2 1185 731 787 1267 1224 Q9ESE1 7.79e-65 Lipopolysaccharide-responsive and beige-like anchor protein (Beige-like protein) Mus musculus (Mouse) cellular response to leukemia inhibitory factor [GO:1990830]; endosomal transport [GO:0016197]; mitophagy [GO:0000423]; protein localization [GO:0008104]; protein localization to phagophore assembly site [GO:0034497]; signal transduction [GO:0007165] GO:0000423; GO:0005764; GO:0005765; GO:0005783; GO:0005789; GO:0005802; GO:0005829; GO:0005886; GO:0007165; GO:0008104; GO:0016020; GO:0016197; GO:0019901; GO:0031410; GO:0034497; GO:0051018; GO:1990830 11722 XR_006397284.1 0 38 0 0 4 NA NA NA NA NA NA 11723 XM_044307337.1 0 0 0 9 0 Q0V8S9 2.73e-25 Contactin-associated protein-like 5 (Cell recognition molecule Caspr5) Gallus gallus (Chicken) cell adhesion [GO:0007155] GO:0007155; GO:0016020 11724 XM_029357022.2 172 0 34 58 95 NA NA NA NA NA NA 11725 XM_044327795.1 1953 407 73 311 8 NA NA NA NA NA NA 11726 XM_029344087.2 293 15 11 22 247 NA NA NA NA NA NA 11727 XM_044329061.1 18 7 6 0 53 NA NA NA NA NA NA 11728 XM_029348243.2 114 172 5 156 76 NA NA NA NA NA NA 11729 XR_003825215.2 31 0 44 0 0 NA NA NA NA NA NA 11730 XM_044308286.1 31 0 12 4 7 Q07598 0 Sterol carrier protein 2 (SCP-2) (Acetyl-CoA C-myristoyltransferase) (EC 2.3.1.155) (Non-specific lipid-transfer protein) (NSL-TP) (Propanoyl-CoA C-acyltransferase) (EC 2.3.1.176) (SCP-2/3-oxoacyl-CoA thiolase) (SCP-2/thiolase) (EC 2.3.1.16) (SCP-chi) (SCPX) (Sterol carrier protein X) (SCP-X) Gallus gallus (Chicken) bile acid metabolic process [GO:0008206]; fatty acid beta-oxidation [GO:0006635]; lipid transport [GO:0006869]; positive regulation of intracellular cholesterol transport [GO:0032385] GO:0003988; GO:0005737; GO:0005739; GO:0005777; GO:0005782; GO:0005783; GO:0006635; GO:0006869; GO:0008206; GO:0008289; GO:0032385; GO:0033814; GO:0050632; GO:0050633; GO:0120019; GO:0120020 11731 XR_006391415.1 211 25 97 15 65 NA NA NA NA NA NA 11732 XM_044310811.1 0 0 5 0 8 NA NA NA NA NA NA 11733 XM_029349637.2 86 4 25 36 109 NA NA NA NA NA NA 11734 XR_006393830.1 1251 276 602 1035 2328 NA NA NA NA NA NA 11735 XM_029340758.2 95 0 0 52 36 P21674 1.03e-37 Follistatin (FS) (Activin-binding protein) Rattus norvegicus (Rat) ameloblast differentiation [GO:0036305]; BMP signaling pathway [GO:0030509]; cell differentiation [GO:0030154]; cellular response to growth factor stimulus [GO:0071363]; female gonad development [GO:0008585]; gamete generation [GO:0007276]; hair follicle morphogenesis [GO:0031069]; hematopoietic progenitor cell differentiation [GO:0002244]; keratinocyte proliferation [GO:0043616]; negative regulation of activin receptor signaling pathway [GO:0032926]; negative regulation of cell differentiation [GO:0045596]; negative regulation of epithelial cell differentiation [GO:0030857]; negative regulation of follicle-stimulating hormone secretion [GO:0046882]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis of dentin-containing tooth [GO:0042475]; pattern specification process [GO:0007389]; positive regulation of hair follicle development [GO:0051798]; regulation of BMP signaling pathway [GO:0030510]; response to organic cyclic compound [GO:0014070]; skeletal system development [GO:0001501] GO:0000122; GO:0001501; GO:0002244; GO:0005615; GO:0005634; GO:0005737; GO:0007276; GO:0007389; GO:0008585; GO:0014070; GO:0030154; GO:0030509; GO:0030510; GO:0030857; GO:0031069; GO:0032926; GO:0036305; GO:0038102; GO:0042475; GO:0043395; GO:0043616; GO:0045596; GO:0046882; GO:0048185; GO:0051798; GO:0071363 11736 XM_029333364.2 669 618 359 480 576 Q5PQQ9 2.94e-31 Centrosomal protein of 70 kDa (Cep70) Rattus norvegicus (Rat) cilium assembly [GO:0060271]; regulation of microtubule cytoskeleton organization [GO:0070507] GO:0005737; GO:0005813; GO:0042802; GO:0043015; GO:0060271; GO:0070507 11737 XM_029345603.2 695 996 233 669 871 Q8TEL6 5.06e-149 Short transient receptor potential channel 4-associated protein (Trp4-associated protein) (Trpc4-associated protein) (Protein TAP1) (TNF-receptor ubiquitous scaffolding/signaling protein) (Protein TRUSS) Homo sapiens (Human) calcium ion transmembrane transport [GO:0070588]; hair follicle maturation [GO:0048820]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent protein catabolic process via the C-end degron rule pathway [GO:0140627] GO:0005262; GO:0005886; GO:0006511; GO:0016567; GO:0019902; GO:0031464; GO:0048471; GO:0048820; GO:0070588; GO:0080008; GO:0140627; GO:1990756 11738 XM_029333289.2 77 0 66 61 50 Q8LHH9 7.89e-146 Probable RNA-dependent RNA polymerase SHL2 (EC 2.7.7.48) (Protein SHOOTLESS 2) Oryza sativa subsp. japonica (Rice) maintenance of shoot apical meristem identity [GO:0010492]; RNA-mediated post-transcriptional gene silencing [GO:0035194]; siRNA processing [GO:0030422] GO:0003723; GO:0003968; GO:0010492; GO:0030422; GO:0031380; GO:0035194 11739 XM_029346029.2 0 0 50 29 73 O75179 4.28e-90 Ankyrin repeat domain-containing protein 17 (Gene trap ankyrin repeat protein) (Serologically defined breast cancer antigen NY-BR-16) Homo sapiens (Human) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0016020; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 11740 XM_029346029.2 0 0 50 29 73 O75179 2.05e-84 Ankyrin repeat domain-containing protein 17 (Gene trap ankyrin repeat protein) (Serologically defined breast cancer antigen NY-BR-16) Homo sapiens (Human) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0016020; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 11741 XM_029346029.2 0 0 50 29 73 O75179 2.93e-69 Ankyrin repeat domain-containing protein 17 (Gene trap ankyrin repeat protein) (Serologically defined breast cancer antigen NY-BR-16) Homo sapiens (Human) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0016020; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 11742 XM_029346029.2 0 0 50 29 73 O75179 1.73e-64 Ankyrin repeat domain-containing protein 17 (Gene trap ankyrin repeat protein) (Serologically defined breast cancer antigen NY-BR-16) Homo sapiens (Human) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0016020; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 11743 XM_029346029.2 0 0 50 29 73 O75179 3.03e-62 Ankyrin repeat domain-containing protein 17 (Gene trap ankyrin repeat protein) (Serologically defined breast cancer antigen NY-BR-16) Homo sapiens (Human) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0016020; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 11744 XM_029346029.2 0 0 50 29 73 O75179 2.81e-58 Ankyrin repeat domain-containing protein 17 (Gene trap ankyrin repeat protein) (Serologically defined breast cancer antigen NY-BR-16) Homo sapiens (Human) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0016020; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 11745 XM_029346029.2 0 0 50 29 73 O75179 1.18e-35 Ankyrin repeat domain-containing protein 17 (Gene trap ankyrin repeat protein) (Serologically defined breast cancer antigen NY-BR-16) Homo sapiens (Human) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0016020; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 11746 XM_029339850.2 205 204 178 172 289 Q9UKD2 7.08e-87 mRNA turnover protein 4 homolog (Ribosome assembly factor MRTO4) Homo sapiens (Human) nuclear-transcribed mRNA catabolic process [GO:0000956]; ribosomal large subunit assembly [GO:0000027]; ribosomal large subunit biogenesis [GO:0042273]; rRNA processing [GO:0006364] GO:0000027; GO:0000956; GO:0003723; GO:0005730; GO:0005737; GO:0006364; GO:0030687; GO:0042273 11747 XR_006395029.1 68 111 121 37 142 NA NA NA NA NA NA 11748 XR_006391913.1 23 4 21 4 66 NA NA NA NA NA NA 11749 XM_044321255.1 797 743 913 676 646 NA NA NA NA NA NA 11750 XM_029330335.2 698 629 388 946 601 P07221 1.14e-57 Calsequestrin-1 (Aspartactin) (Calsequestrin, skeletal muscle isoform) (Laminin-binding protein) Oryctolagus cuniculus (Rabbit) positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of store-operated calcium channel activity [GO:1901341]; protein polymerization [GO:0051258]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; regulation of store-operated calcium entry [GO:2001256]; sarcomere organization [GO:0045214]; sequestering of metal ion [GO:0051238] GO:0000287; GO:0005509; GO:0005759; GO:0014809; GO:0016529; GO:0030955; GO:0033017; GO:0033018; GO:0042803; GO:0043167; GO:0045214; GO:0046872; GO:0051238; GO:0051258; GO:0051281; GO:1901341; GO:2001256 11751 XM_029349476.2 648 542 412 621 602 Q8BID8 2.74e-30 F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14) Mus musculus (Mouse) SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004842; GO:0005737; GO:0006511; GO:0019005; GO:0031146 11752 XM_029349476.2 648 542 412 621 602 Q8BID8 5.07e-26 F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14) Mus musculus (Mouse) SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004842; GO:0005737; GO:0006511; GO:0019005; GO:0031146 11753 XM_044317944.1 401 416 428 388 254 NA NA NA NA NA NA 11754 XM_029330576.2 479 323 315 463 594 P0DTA4 0 Propionyl-CoA carboxylase alpha chain, mitochondrial (PCCase subunit alpha) (EC 6.4.1.3) (Propanoyl-CoA:carbon dioxide ligase subunit alpha) Sus scrofa (Pig) short-chain fatty acid catabolic process [GO:0019626] GO:0004658; GO:0005524; GO:0005759; GO:0019626; GO:0046872 11755 XM_029347876.2 659 1526 1152 1368 863 NA NA NA NA NA NA 11756 XM_044319956.1 5 12 0 0 3 Q6LAF1 7.52e-49 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 11757 XM_029338769.2 3493 2660 1242 3486 2536 P42325 2.26e-116 Neurocalcin homolog (DrosNCa) Drosophila melanogaster (Fruit fly) negative regulation of neuronal signal transduction [GO:1902848]; positive regulation of circadian sleep/wake cycle, sleep [GO:0045938] GO:0005509; GO:0045938; GO:1902848 11758 XM_029331421.2 2006 1793 1134 1572 1554 Q64674 2.56e-131 Spermidine synthase (SPDSY) (EC 2.5.1.16) (Putrescine aminopropyltransferase) Mus musculus (Mouse) cellular response to leukemia inhibitory factor [GO:1990830]; polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295] GO:0004766; GO:0006596; GO:0008295; GO:0042802; GO:0042803; GO:1990830 11759 XM_029342087.2 172 160 65 199 178 P42893 0 Endothelin-converting enzyme 1 (ECE-1) (EC 3.4.24.71) Rattus norvegicus (Rat) apoptotic process [GO:0006915]; axonogenesis involved in innervation [GO:0060385]; blood vessel diameter maintenance [GO:0097746]; bradykinin catabolic process [GO:0010815]; calcitonin catabolic process [GO:0010816]; ear development [GO:0043583]; embryonic digit morphogenesis [GO:0042733]; embryonic heart tube development [GO:0035050]; endothelin maturation [GO:0034959]; gene expression [GO:0010467]; heart development [GO:0007507]; hormone catabolic process [GO:0042447]; neuron projection development [GO:0031175]; peptide hormone processing [GO:0016486]; pharyngeal system development [GO:0060037]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of receptor recycling [GO:0001921]; protein processing [GO:0016485]; regulation of blood pressure [GO:0008217]; regulation of ERK1 and ERK2 cascade [GO:0070372]; response to cadmium ion [GO:0046686]; response to hypoxia [GO:0001666]; response to muscle stretch [GO:0035994]; response to xenobiotic stimulus [GO:0009410]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; substance P catabolic process [GO:0010814]; sympathetic neuron axon guidance [GO:0097492] GO:0001666; GO:0001921; GO:0004175; GO:0004222; GO:0005768; GO:0005769; GO:0005886; GO:0006915; GO:0007507; GO:0008217; GO:0008270; GO:0009410; GO:0009897; GO:0010467; GO:0010613; GO:0010814; GO:0010815; GO:0010816; GO:0016020; GO:0016485; GO:0016486; GO:0030141; GO:0031175; GO:0031410; GO:0031982; GO:0033093; GO:0034959; GO:0035050; GO:0035994; GO:0042447; GO:0042733; GO:0042802; GO:0042803; GO:0043583; GO:0043950; GO:0045745; GO:0046686; GO:0048471; GO:0060037; GO:0060385; GO:0070372; GO:0097492; GO:0097746; GO:1902287 11760 XM_029336593.2 664 579 582 1426 1160 Q5XIN3 1.36e-51 TRAF3-interacting protein 1 (Intraflagellar transport protein 54 homolog) (Microtubule-interacting protein associated with TRAF3) (MIP-T3) Rattus norvegicus (Rat) cilium assembly [GO:0060271]; defense response to virus [GO:0051607]; embryonic camera-type eye development [GO:0031076]; embryonic digit morphogenesis [GO:0042733]; embryonic heart tube development [GO:0035050]; intraciliary transport [GO:0042073]; kidney development [GO:0001822]; morphogenesis of a polarized epithelium [GO:0001738]; negative regulation of defense response to virus [GO:0050687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:1901621]; negative regulation of type I interferon production [GO:0032480]; neural tube patterning [GO:0021532]; post-anal tail morphogenesis [GO:0036342]; regulation of microtubule cytoskeleton organization [GO:0070507]; smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] GO:0001738; GO:0001822; GO:0001933; GO:0005813; GO:0005929; GO:0005930; GO:0008017; GO:0021532; GO:0030992; GO:0031076; GO:0031333; GO:0032480; GO:0032688; GO:0035050; GO:0035869; GO:0036064; GO:0036342; GO:0042073; GO:0042733; GO:0050687; GO:0051607; GO:0060271; GO:0060831; GO:0070507; GO:0097542; GO:0097546; GO:1901621 11761 XM_029336593.2 664 579 582 1426 1160 Q5XIN3 7.06e-47 TRAF3-interacting protein 1 (Intraflagellar transport protein 54 homolog) (Microtubule-interacting protein associated with TRAF3) (MIP-T3) Rattus norvegicus (Rat) cilium assembly [GO:0060271]; defense response to virus [GO:0051607]; embryonic camera-type eye development [GO:0031076]; embryonic digit morphogenesis [GO:0042733]; embryonic heart tube development [GO:0035050]; intraciliary transport [GO:0042073]; kidney development [GO:0001822]; morphogenesis of a polarized epithelium [GO:0001738]; negative regulation of defense response to virus [GO:0050687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:1901621]; negative regulation of type I interferon production [GO:0032480]; neural tube patterning [GO:0021532]; post-anal tail morphogenesis [GO:0036342]; regulation of microtubule cytoskeleton organization [GO:0070507]; smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] GO:0001738; GO:0001822; GO:0001933; GO:0005813; GO:0005929; GO:0005930; GO:0008017; GO:0021532; GO:0030992; GO:0031076; GO:0031333; GO:0032480; GO:0032688; GO:0035050; GO:0035869; GO:0036064; GO:0036342; GO:0042073; GO:0042733; GO:0050687; GO:0051607; GO:0060271; GO:0060831; GO:0070507; GO:0097542; GO:0097546; GO:1901621 11762 XM_044313725.1 22 25 2 6 5 Q2KJC3 5.94e-148 Macrophage-expressed gene 1 protein (Macrophage gene 1 protein) (Mpg-1) (Perforin-2) (P-2) Bos taurus (Bovine) antibacterial innate immune response [GO:0140367]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; disruption by host of symbiont membrane [GO:0052337] GO:0030659; GO:0031410; GO:0042742; GO:0045335; GO:0050829; GO:0050830; GO:0052337; GO:0140367 11763 XM_029357835.2 41 41 36 15 160 Q5XXP2 6.85e-28 Melanopsin (Opsin-4) Phodopus sungorus (Striped hairy-footed hamster) (Djungarian hamster) hyaloid vascular plexus regression [GO:1990384]; optokinetic behavior [GO:0007634]; phototransduction [GO:0007602]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511]; visual perception [GO:0007601] GO:0005502; GO:0005886; GO:0007601; GO:0007602; GO:0007634; GO:0008020; GO:0016020; GO:0030424; GO:0030425; GO:0042752; GO:0043204; GO:0048511; GO:1990384 11764 XR_006393372.1 8 1 7 0 5 NA NA NA NA NA NA 11765 XM_029331078.2 6328 16587 6100 10234 3972 Q5I0R4 4.2e-88 Cilia- and flagella-associated protein 300 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737; GO:0005856; GO:0031514 11766 XM_044322361.1 199 68 99 165 277 Q7TN88 9.51e-56 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 11767 XM_044322361.1 199 68 99 165 277 Q7TN88 1.05e-52 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 11768 XM_044308819.1 164 132 310 130 184 NA NA NA NA NA NA 11769 XM_029330114.2 10 3 0 0 0 H1AFJ5 2.33e-45 Amiloride-sensitive sodium channel subunit alpha (Alpha-NaCH) (Epithelial Na(+) channel subunit alpha) (Alpha-ENaC) (Nonvoltage-gated sodium channel 1 subunit alpha) (SCNEA) Neoceratodus forsteri (Australian lungfish) (Ceratodus forsteri) sodium ion transmembrane transport [GO:0035725] GO:0001669; GO:0005737; GO:0015280; GO:0016324; GO:0031514; GO:0034706; GO:0035725 11770 XM_029334718.2 961 280 446 115 298 Q66JY2 8.15e-39 INO80 complex subunit D Mus musculus (Mouse) chromatin remodeling [GO:0006338]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of telomere maintenance in response to DNA damage [GO:1904507]; regulation of cell cycle [GO:0051726]; regulation of chromosome organization [GO:0033044]; regulation of DNA repair [GO:0006282]; regulation of DNA replication [GO:0006275]; regulation of DNA strand elongation [GO:0060382]; regulation of embryonic development [GO:0045995]; telomere maintenance [GO:0000723] GO:0000723; GO:0005634; GO:0006275; GO:0006281; GO:0006282; GO:0006310; GO:0006338; GO:0031011; GO:0033044; GO:0045739; GO:0045893; GO:0045995; GO:0051726; GO:0060382; GO:1904507 11771 XM_044314511.1 0 0 2 0 26 NA NA NA NA NA NA 11772 XM_044307274.1 263 155 227 185 166 NA NA NA NA NA NA 11773 XM_044306887.1 118 65 52 86 236 Q8BGE5 0 Fanconi anemia group M protein homolog (Protein FACM) (EC 3.6.4.13) (ATP-dependent RNA helicase FANCM) Mus musculus (Mouse) double-strand break repair via synthesis-dependent strand annealing [GO:0045003]; interstrand cross-link repair [GO:0036297]; positive regulation of protein monoubiquitination [GO:1902527]; replication fork processing [GO:0031297]; replication fork reversal [GO:0071932]; resolution of meiotic recombination intermediates [GO:0000712] GO:0000400; GO:0000712; GO:0000785; GO:0003682; GO:0003724; GO:0004518; GO:0005524; GO:0005654; GO:0009378; GO:0016887; GO:0031297; GO:0036297; GO:0043138; GO:0043240; GO:0045003; GO:0071821; GO:0071932; GO:1902527 11774 XM_044306887.1 118 65 52 86 236 Q8BGE5 6.31e-43 Fanconi anemia group M protein homolog (Protein FACM) (EC 3.6.4.13) (ATP-dependent RNA helicase FANCM) Mus musculus (Mouse) double-strand break repair via synthesis-dependent strand annealing [GO:0045003]; interstrand cross-link repair [GO:0036297]; positive regulation of protein monoubiquitination [GO:1902527]; replication fork processing [GO:0031297]; replication fork reversal [GO:0071932]; resolution of meiotic recombination intermediates [GO:0000712] GO:0000400; GO:0000712; GO:0000785; GO:0003682; GO:0003724; GO:0004518; GO:0005524; GO:0005654; GO:0009378; GO:0016887; GO:0031297; GO:0036297; GO:0043138; GO:0043240; GO:0045003; GO:0071821; GO:0071932; GO:1902527 11775 XR_006395018.1 100 318 112 296 249 NA NA NA NA NA NA 11776 XR_006395839.1 29 0 5 17 53 NA NA NA NA NA NA 11777 XM_044310518.1 97 77 79 123 53 NA NA NA NA NA NA 11778 XM_029345482.2 100 59 19 18 108 NA NA NA NA NA NA 11779 XM_029332235.2 1456 694 904 1083 2071 Q8R3S6 0 Exocyst complex component 1 (Exocyst complex component Sec3) Mus musculus (Mouse) embryo implantation [GO:0007566]; exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; membrane fission [GO:0090148]; mitotic cytokinesis [GO:0000281]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of protein secretion [GO:0050714]; protein transport [GO:0015031]; vesicle docking involved in exocytosis [GO:0006904]; vesicle tethering involved in exocytosis [GO:0090522] GO:0000145; GO:0000281; GO:0005546; GO:0005737; GO:0005886; GO:0006887; GO:0006893; GO:0006904; GO:0007566; GO:0015031; GO:0048015; GO:0048471; GO:0050714; GO:0090148; GO:0090522; GO:0090543; GO:0098592 11780 XM_044321229.1 66 69 36 95 196 Q7RTR2 4.02e-29 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11781 XM_044321229.1 66 69 36 95 196 Q7RTR2 7.42e-25 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11782 XM_044321229.1 66 69 36 95 196 Q7RTR2 2.06e-21 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11783 XM_029352417.2 0 26 0 168 7 A6H603 4.84e-92 NACHT domain- and WD repeat-containing protein 1 Mus musculus (Mouse) negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of gene expression [GO:0010628] GO:0005524; GO:0005730; GO:0005829; GO:0010628; GO:0032088 11784 XM_029323908.2 12514 9806 5815 8366 13158 Q27433 1.47e-109 Mechanosensory protein 2 Caenorhabditis elegans detection of mechanical stimulus involved in sensory perception of touch [GO:0050976]; mechanosensory behavior [GO:0007638]; positive regulation of detection of mechanical stimulus involved in sensory perception of touch [GO:1905789]; positive regulation of mechanosensory behavior [GO:1905792]; potassium ion transport [GO:0006813]; response to mechanical stimulus [GO:0009612] GO:0005272; GO:0005886; GO:0006813; GO:0007638; GO:0009612; GO:0015485; GO:0032589; GO:0043005; GO:0050976; GO:1905789; GO:1905792 11785 XM_044316376.1 0 0 14 0 0 NA NA NA NA NA NA 11786 XM_029355537.2 223 133 77 210 303 Q15542 0 Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100) Homo sapiens (Human) DNA-templated transcription initiation [GO:0006352]; histone H3 acetylation [GO:0043966]; monoubiquitinated histone deubiquitination [GO:0035521]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; mRNA transcription by RNA polymerase II [GO:0042789]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription initiation at RNA polymerase II promoter [GO:0006367] GO:0000785; GO:0005634; GO:0005654; GO:0005669; GO:0006282; GO:0006352; GO:0006357; GO:0006367; GO:0006468; GO:0015629; GO:0016251; GO:0033276; GO:0035521; GO:0035522; GO:0042789; GO:0042802; GO:0043966; GO:0045893; GO:0051123; GO:0060261 11787 XR_003826220.2 12 0 4 0 18 NA NA NA NA NA NA 11788 XM_029344193.2 4741 1719 1592 2023 1592 NA NA NA NA NA NA 11789 XR_006396141.1 0 3 3 18 12 NA NA NA NA NA NA 11790 XR_006394189.1 0 6 0 0 0 NA NA NA NA NA NA 11791 XR_006396490.1 0 0 0 9 0 NA NA NA NA NA NA 11792 XM_044320452.1 1566 1622 1060 1343 1724 Q7SXW4 6.77e-113 ER membrane protein complex subunit 3 (Protein pob) (Transmembrane protein 111) Danio rerio (Zebrafish) (Brachydanio rerio) photoreceptor cell maintenance [GO:0045494]; protein insertion into ER membrane by stop-transfer membrane-anchor sequence [GO:0045050]; retina development in camera-type eye [GO:0060041]; tail-anchored membrane protein insertion into ER membrane [GO:0071816] GO:0005789; GO:0005794; GO:0016020; GO:0030140; GO:0045050; GO:0045494; GO:0060041; GO:0071816; GO:0072546 11793 XM_029348748.2 1398 996 642 951 818 A0JPI9 3.21e-95 Leucine-rich repeat-containing protein 74A (Leucine-rich repeat-containing protein 74) Rattus norvegicus (Rat) NA NA 11794 XM_029358363.2 577 132 142 373 165 Q62824 0 Exocyst complex component 4 (Exocyst complex component Sec8) (rSec8) Rattus norvegicus (Rat) chemical synaptic transmission [GO:0007268]; establishment of cell polarity [GO:0030010]; exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; Golgi to transport vesicle transport [GO:0055108]; membrane biogenesis [GO:0044091]; oligodendrocyte differentiation [GO:0048709]; paraxial mesoderm formation [GO:0048341]; positive regulation of calcium-mediated signaling [GO:0050850]; protein targeting to membrane [GO:0006612]; regulation of protein transport [GO:0051223]; vesicle docking involved in exocytosis [GO:0006904]; vesicle targeting [GO:0006903]; vesicle tethering involved in exocytosis [GO:0090522] GO:0000145; GO:0005813; GO:0005902; GO:0006612; GO:0006887; GO:0006893; GO:0006903; GO:0006904; GO:0007268; GO:0008021; GO:0014069; GO:0016020; GO:0030010; GO:0030165; GO:0030425; GO:0030426; GO:0031252; GO:0031267; GO:0032584; GO:0032991; GO:0035255; GO:0035748; GO:0043005; GO:0043025; GO:0043198; GO:0043209; GO:0044091; GO:0044877; GO:0045202; GO:0047485; GO:0048341; GO:0048709; GO:0050850; GO:0051223; GO:0055108; GO:0090522; GO:0090543; GO:0098685; GO:0099092 11795 XM_029345986.2 1416 961 503 1579 1569 O55230 2.48e-67 DNA repair protein RAD51 homolog 4 (R51H3) (RAD51 homolog D) (RAD51-like protein 3) Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; chromosome organization [GO:0051276]; double-strand break repair via homologous recombination [GO:0000724]; interstrand cross-link repair [GO:0036297]; reciprocal meiotic recombination [GO:0007131]; regulation of cell cycle [GO:0051726]; strand invasion [GO:0042148]; telomere maintenance [GO:0000723]; telomere maintenance via recombination [GO:0000722] GO:0000400; GO:0000722; GO:0000723; GO:0000724; GO:0000781; GO:0003697; GO:0005524; GO:0005657; GO:0005813; GO:0006974; GO:0007131; GO:0008094; GO:0033063; GO:0036297; GO:0042148; GO:0043015; GO:0051276; GO:0051726; GO:0140664 11796 XM_044326900.1 12 43 9 30 75 NA NA NA NA NA NA 11797 XM_044319912.1 0 1 23 0 15 Q3V050 2.71e-73 Multidrug and toxin extrusion protein 2 (MATE-2) (mMATE-2) (H(+)/organic cation antiporter kidney-specific) (Solute carrier family 47 member 2) Mus musculus (Mouse) organic cation transport [GO:0015695]; xenobiotic detoxification by transmembrane export across the plasma membrane [GO:1990961] GO:0005886; GO:0015101; GO:0015179; GO:0015297; GO:0015299; GO:0015695; GO:0016020; GO:0016323; GO:0016324; GO:0022857; GO:0042910; GO:0061459; GO:1990961 11798 XM_029349815.2 260 282 178 208 257 Q08B12 9.83e-79 Cytoplasmic tRNA 2-thiolation protein 2-A Xenopus laevis (African clawed frog) protein urmylation [GO:0032447]; tRNA thio-modification [GO:0034227]; tRNA wobble uridine modification [GO:0002098] GO:0000049; GO:0002098; GO:0005829; GO:0016779; GO:0032447; GO:0034227 11799 XM_044309856.1 702 430 372 770 889 A2RT67 7.02e-104 DENN domain-containing protein 3 Mus musculus (Mouse) endosome to lysosome transport [GO:0008333]; protein catabolic process [GO:0030163]; regulation of Rab protein signal transduction [GO:0032483] GO:0005085; GO:0008333; GO:0030163; GO:0031410; GO:0032483 11800 XM_044324826.1 0 1 54 0 3 P84239 7.59e-95 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 11801 XM_044327624.1 153 86 42 77 125 Q8WV83 4.53e-109 Solute carrier family 35 member F5 (Hepatitis C virus NS5A-transactivated protein 3) (HCV NS5A-transactivated protein 3) Homo sapiens (Human) NA GO:0016020 11802 XM_029330389.2 50748 43718 33735 51035 39986 P18321 2.25e-79 Profilin Clypeaster japonicus (Sand dollar) regulation of cellular component biogenesis [GO:0044087] GO:0003779; GO:0005737; GO:0005856; GO:0044087 11803 XR_003826845.2 17 56 79 53 97 NA NA NA NA NA NA 11804 XM_044318680.1 38 77 0 131 95 Q6B858 1.59e-95 Fibronectin type 3 and ankyrin repeat domains protein 1 (GV14) Bos taurus (Bovine) positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of apoptotic process [GO:0042981] GO:0005634; GO:0005829; GO:0005929; GO:0036064; GO:0042981; GO:0045893; GO:0051091 11805 XM_029330134.2 356 197 307 484 488 Q8VHR5 3.34e-33 Transcriptional repressor p66-beta (GATA zinc finger domain-containing protein 2B) (p66/p68) Mus musculus (Mouse) chromatin remodeling [GO:0006338]; histone deacetylation [GO:0016575]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of cell fate specification [GO:0042659]; regulation of stem cell differentiation [GO:2000736] GO:0000122; GO:0000781; GO:0005634; GO:0005654; GO:0006338; GO:0008270; GO:0016575; GO:0016581; GO:0016607; GO:0042659; GO:0043565; GO:0045892; GO:0045893; GO:2000736 11806 XM_044311592.1 0 0 2 9 0 NA NA NA NA NA NA 11807 XM_029340287.2 665 400 374 647 702 O94880 1.45e-152 PHD finger protein 14 Homo sapiens (Human) germinal center B cell differentiation [GO:0002314]; lung alveolus development [GO:0048286]; mesenchymal cell proliferation [GO:0010463]; mesenchymal cell proliferation involved in lung development [GO:0060916]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of mesenchymal cell proliferation [GO:0072201]; negative regulation of mesenchymal cell proliferation involved in lung development [GO:2000791]; negative regulation of platelet-derived growth factor receptor-alpha signaling pathway [GO:2000584]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000785; GO:0002314; GO:0005634; GO:0005737; GO:0006357; GO:0008270; GO:0008285; GO:0010463; GO:0042393; GO:0048286; GO:0060916; GO:0070776; GO:0072201; GO:0140566; GO:2000584; GO:2000791 11808 XM_044324033.1 1495 797 634 1781 1512 B0R0T1 0 von Willebrand factor A domain-containing protein 8 Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005524; GO:0005737; GO:0005739; GO:0016887 11809 XM_029328343.2 202 142 71 185 200 F4HYF3 1.63e-78 Bifunctional D-cysteine desulfhydrase/1-aminocyclopropane-1-carboxylate deaminase, mitochondrial (EC 3.5.99.7) (EC 4.4.1.15) (1-aminocyclopropane-1-carboxylic acid deaminase 1) (AtACD1) (AtD-CDes1) (D-CDes1) (D-CDES) Arabidopsis thaliana (Mouse-ear cress) D-cysteine catabolic process [GO:0019447]; ethylene biosynthetic process [GO:0009693]; stress response to cadmium ion [GO:1990170] GO:0005634; GO:0005739; GO:0005829; GO:0009507; GO:0009693; GO:0016787; GO:0019148; GO:0019447; GO:0050897; GO:1990170 11810 XM_044323530.1 206 181 164 390 195 NA NA NA NA NA NA 11811 XM_029339653.2 699 1246 552 1979 671 A0A2B4SJA1 1.95e-103 NA NA NA NA 11812 XM_029357088.2 195 190 93 160 108 Q05B21 3.1e-122 Vesicular glutamate transporter 1 (VGluT1) (Solute carrier family 17 member 7) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) chloride transport [GO:0006821]; L-glutamate transmembrane transport [GO:0015813]; neurotransmitter transport [GO:0006836]; phosphate ion transport [GO:0006817]; potassium ion transport [GO:0006813]; sodium-dependent phosphate transport [GO:0044341] GO:0005254; GO:0005436; GO:0005886; GO:0006813; GO:0006817; GO:0006821; GO:0006836; GO:0015386; GO:0015813; GO:0030672; GO:0034707; GO:0043005; GO:0044341; GO:0140787; GO:0140788 11813 XM_029357088.2 195 190 93 160 108 Q05B21 7.5e-115 Vesicular glutamate transporter 1 (VGluT1) (Solute carrier family 17 member 7) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) chloride transport [GO:0006821]; L-glutamate transmembrane transport [GO:0015813]; neurotransmitter transport [GO:0006836]; phosphate ion transport [GO:0006817]; potassium ion transport [GO:0006813]; sodium-dependent phosphate transport [GO:0044341] GO:0005254; GO:0005436; GO:0005886; GO:0006813; GO:0006817; GO:0006821; GO:0006836; GO:0015386; GO:0015813; GO:0030672; GO:0034707; GO:0043005; GO:0044341; GO:0140787; GO:0140788 11814 XM_044318866.1 64 24 54 123 200 NA NA NA NA NA NA 11815 XM_044320356.1 2801 4039 2885 4029 2393 Q13501 1.31e-25 Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62) Homo sapiens (Human) aggrephagy [GO:0035973]; apoptotic process [GO:0006915]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; brown fat cell proliferation [GO:0070342]; cell differentiation [GO:0030154]; endosomal transport [GO:0016197]; endosome organization [GO:0007032]; energy homeostasis [GO:0097009]; immune system process [GO:0002376]; intracellular signal transduction [GO:0035556]; macroautophagy [GO:0016236]; mitophagy [GO:0000423]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pexophagy [GO:0000425]; positive regulation of apoptotic process [GO:0043065]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein localization to perinuclear region of cytoplasm [GO:1905719]; protein phosphorylation [GO:0006468]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mitochondrion organization [GO:0010821]; regulation of protein complex stability [GO:0061635]; regulation of Ras protein signal transduction [GO:0046578]; response to ischemia [GO:0002931]; response to mitochondrial depolarisation [GO:0098780]; selective autophagy [GO:0061912]; temperature homeostasis [GO:0001659]; transcription by RNA polymerase II [GO:0006366]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000122; GO:0000407; GO:0000422; GO:0000423; GO:0000425; GO:0000932; GO:0001659; GO:0001934; GO:0002376; GO:0002931; GO:0004674; GO:0005080; GO:0005654; GO:0005737; GO:0005739; GO:0005770; GO:0005776; GO:0005783; GO:0005829; GO:0006366; GO:0006468; GO:0006511; GO:0006606; GO:0006914; GO:0006915; GO:0007032; GO:0008104; GO:0008270; GO:0010821; GO:0016197; GO:0016234; GO:0016235; GO:0016236; GO:0016605; GO:0019899; GO:0019901; GO:0030017; GO:0030154; GO:0030674; GO:0030971; GO:0031397; GO:0031625; GO:0035255; GO:0035556; GO:0035973; GO:0042169; GO:0042802; GO:0043065; GO:0043122; GO:0043130; GO:0043231; GO:0044753; GO:0044754; GO:0044877; GO:0045944; GO:0046578; GO:0061635; GO:0061912; GO:0070062; GO:0070342; GO:0070530; GO:0097009; GO:0097225; GO:0097413; GO:0098780; GO:1900273; GO:1903078; GO:1905719 11816 XM_044326284.1 22 111 40 41 44 NA NA NA NA NA NA 11817 XM_044314554.1 129 245 30 51 28 Q80WG5 5.39e-68 Volume-regulated anion channel subunit LRRC8A (Leucine-rich repeat-containing protein 8A) (Protein ebouriffe) (ebo) Mus musculus (Mouse) anion transmembrane transport [GO:0098656]; anion transport [GO:0006820]; aspartate transmembrane transport [GO:0015810]; cell volume homeostasis [GO:0006884]; cellular glucose homeostasis [GO:0001678]; chloride transmembrane transport [GO:1902476]; cyclic-GMP-AMP transmembrane import across plasma membrane [GO:0140361]; positive regulation of insulin secretion [GO:0032024]; positive regulation of myoblast differentiation [GO:0045663]; pre-B cell differentiation [GO:0002329]; protein hexamerization [GO:0034214]; response to osmotic stress [GO:0006970]; spermatogenesis [GO:0007283]; taurine transport [GO:0015734] GO:0001678; GO:0002329; GO:0005225; GO:0005253; GO:0005765; GO:0005886; GO:0006820; GO:0006884; GO:0006970; GO:0007283; GO:0009986; GO:0015734; GO:0015810; GO:0016020; GO:0032024; GO:0034214; GO:0034702; GO:0042802; GO:0045663; GO:0098656; GO:0140360; GO:0140361; GO:1902476 11818 XR_006394184.1 83 14 2 0 0 NA NA NA NA NA NA 11819 XM_044325167.1 0 0 62 0 127 NA NA NA NA NA NA 11820 XM_029340587.2 859 374 397 643 732 Q16706 0 Alpha-mannosidase 2 (EC 3.2.1.114) (Golgi alpha-mannosidase II) (AMan II) (Man II) (Mannosidase alpha class 2A member 1) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase) Homo sapiens (Human) in utero embryonic development [GO:0001701]; liver development [GO:0001889]; lung alveolus development [GO:0048286]; mannose metabolic process [GO:0006013]; mitochondrion organization [GO:0007005]; N-glycan processing [GO:0006491]; positive regulation of neurogenesis [GO:0050769]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; respiratory gaseous exchange by respiratory system [GO:0007585]; retina morphogenesis in camera-type eye [GO:0060042]; vacuole organization [GO:0007033]; viral protein processing [GO:0019082] GO:0000139; GO:0001701; GO:0001889; GO:0004559; GO:0004572; GO:0005797; GO:0005801; GO:0006013; GO:0006486; GO:0006491; GO:0006517; GO:0007005; GO:0007033; GO:0007585; GO:0016020; GO:0016799; GO:0019082; GO:0030246; GO:0042803; GO:0046872; GO:0048286; GO:0050769; GO:0060042; GO:0070062 11821 XM_044311021.1 189 40 115 116 32 Q9UJG1 3.4e-48 Motile sperm domain-containing protein 1 Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000122; GO:0000139; GO:0005634; GO:0005737; GO:0005789; GO:0030154; GO:0045944; GO:0048471 11822 XR_003826356.2 14 5 7 2 4 NA NA NA NA NA NA 11823 XM_044312932.1 76 145 103 150 145 Q5RED7 7.96e-72 Acylglycerol kinase, mitochondrial (EC 2.7.1.107) (EC 2.7.1.138) (EC 2.7.1.94) (Multiple substrate lipid kinase) (MuLK) (Multi-substrate lipid kinase) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) ceramide biosynthetic process [GO:0046513]; glycerolipid metabolic process [GO:0046486]; protein insertion into mitochondrial inner membrane [GO:0045039] GO:0001729; GO:0004143; GO:0005524; GO:0005743; GO:0005758; GO:0031966; GO:0042721; GO:0045039; GO:0046486; GO:0046513; GO:0047620; GO:0102773 11824 XM_044328479.1 223 169 83 205 333 Q6P4S8 0 Integrator complex subunit 1 (Int1) Mus musculus (Mouse) blastocyst growth [GO:0001832]; inner cell mass cell proliferation [GO:0001833]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; snRNA processing [GO:0016180]; U2 snRNA 3'-end processing [GO:0034474] GO:0001832; GO:0001833; GO:0005634; GO:0016180; GO:0031965; GO:0032039; GO:0034474; GO:0043066; GO:0043154 11825 XR_006397868.1 0 95 49 0 127 Q86U44 3.79e-165 N6-adenosine-methyltransferase catalytic subunit (EC 2.1.1.348) (Methyltransferase-like protein 3) (hMETTL3) (N6-adenosine-methyltransferase 70 kDa subunit) (MT-A70) Homo sapiens (Human) adenosine to inosine editing [GO:0006382]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; circadian rhythm [GO:0007623]; dosage compensation by inactivation of X chromosome [GO:0009048]; endothelial to hematopoietic transition [GO:0098508]; forebrain radial glial cell differentiation [GO:0021861]; gliogenesis [GO:0042063]; innate immune response [GO:0045087]; mRNA catabolic process [GO:0006402]; mRNA destabilization [GO:0061157]; mRNA methylation [GO:0080009]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; oogenesis [GO:0048477]; positive regulation of cap-independent translational initiation [GO:1903679]; positive regulation of translation [GO:0045727]; primary miRNA processing [GO:0031053]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of meiotic cell cycle [GO:0051445]; regulation of T cell differentiation [GO:0045580]; RNA methylation [GO:0001510]; spermatogenesis [GO:0007283]; stem cell population maintenance [GO:0019827] GO:0000398; GO:0001510; GO:0001734; GO:0003729; GO:0005634; GO:0005654; GO:0005737; GO:0006382; GO:0006397; GO:0006402; GO:0006974; GO:0007283; GO:0007623; GO:0008168; GO:0008173; GO:0009048; GO:0016422; GO:0016607; GO:0019827; GO:0021861; GO:0031053; GO:0034644; GO:0036396; GO:0042063; GO:0045087; GO:0045580; GO:0045727; GO:0045746; GO:0046982; GO:0048477; GO:0051445; GO:0060339; GO:0061157; GO:0080009; GO:0098508; GO:1902036; GO:1903679; GO:1904047 11826 XM_044321566.1 107 81 58 177 63 Q96IZ5 2.08e-57 RNA-binding protein 41 (RNA-binding motif protein 41) Homo sapiens (Human) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0005689; GO:0030626; GO:0097157 11827 XM_044316301.1 8 0 7 1 0 NA NA NA NA NA NA 11828 XM_044315136.1 6337 1674 36 1681 11 NA NA NA NA NA NA 11829 XM_029342970.2 0 0 0 0 28 NA NA NA NA NA NA 11830 XM_029345499.2 592 127 296 282 212 Q08DY9 1.93e-32 Caspase-3 (CASP-3) (EC 3.4.22.56) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12] Bos taurus (Bovine) positive regulation of amyloid-beta formation [GO:1902004]; proteolysis [GO:0006508]; regulation of protein stability [GO:0031647] GO:0004175; GO:0005737; GO:0006508; GO:0031647; GO:0097153; GO:0097199; GO:0097200; GO:1902004 11831 XM_044319724.1 0 16 0 0 0 Q9VS29 5.39e-27 Cell adhesion molecule Dscam2 (Down syndrome cell adhesion molecule-like protein Dscam2) Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; dendrite self-avoidance [GO:0070593]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron projection morphogenesis [GO:0048812] GO:0005886; GO:0007156; GO:0007411; GO:0030424; GO:0042802; GO:0048812; GO:0070593; GO:0098632 11832 XM_044319724.1 0 16 0 0 0 Q9VS29 2.29e-22 Cell adhesion molecule Dscam2 (Down syndrome cell adhesion molecule-like protein Dscam2) Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; dendrite self-avoidance [GO:0070593]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron projection morphogenesis [GO:0048812] GO:0005886; GO:0007156; GO:0007411; GO:0030424; GO:0042802; GO:0048812; GO:0070593; GO:0098632 11833 XR_006396449.1 29 0 64 149 70 NA NA NA NA NA NA 11834 XR_003828400.2 2805 3340 2283 2568 2756 NA NA NA NA NA NA 11835 XR_003828176.1 4 4 0 1 41 NA NA NA NA NA NA 11836 XM_029355479.2 2327 1502 936 2330 1272 Q642M9 3.89e-100 Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) (D-xylose 1-dehydrogenase) (D-xylose-NADP dehydrogenase) (EC 1.1.1.179) (Dimeric dihydrodiol dehydrogenase) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0000166; GO:0047115; GO:0047837 11837 XM_029332359.2 1 4 2 0 7 NA NA NA NA NA NA 11838 XR_006397742.1 45 37 74 43 0 NA NA NA NA NA NA 11839 XM_029341807.2 0 0 0 167 0 A0JN80 0 DIS3-like exonuclease 1 (EC 3.1.13.-) Bos taurus (Bovine) rRNA catabolic process [GO:0016075] GO:0000175; GO:0000177; GO:0000178; GO:0003723; GO:0016075; GO:0031090 11840 XM_029331917.2 227 165 139 240 227 Q7T2Z5 1.8e-69 Netrin receptor UNC5C (Protein unc-5 homolog 3) (cUNC-5H3) (Protein unc-5 homolog C) Gallus gallus (Chicken) axon guidance [GO:0007411]; dorsal root ganglion development [GO:1990791] GO:0005042; GO:0005886; GO:0007411; GO:0009986; GO:0030027; GO:0030175; GO:0030425; GO:0030426; GO:0045202; GO:1990791 11841 XM_029344060.2 97 0 0 0 76 NA NA NA NA NA NA 11842 XM_029353496.2 5689 6322 3615 5511 2168 Q9GT45 1.19e-57 40S ribosomal protein S26 Anopheles gambiae (African malaria mosquito) cytoplasmic translation [GO:0002181] GO:0002181; GO:0003729; GO:0003735; GO:0022627; GO:0042788; GO:0098556 11843 XM_029346001.2 1101 583 425 790 905 O70546 0 Lysine-specific demethylase 6A (EC 1.14.11.68) (Histone demethylase UTX) (Ubiquitously transcribed TPR protein on the X chromosome) (Ubiquitously transcribed X chromosome tetratricopeptide repeat protein) ([histone H3]-trimethyl-L-lysine(27) demethylase 6A) Mus musculus (Mouse) cellular response to vitamin D [GO:0071305]; chromatin remodeling [GO:0006338]; circulatory system development [GO:0072359]; embryonic organ development [GO:0048568]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; histone H3-K27 demethylation [GO:0071557]; in utero embryonic development [GO:0001701]; mesodermal cell differentiation [GO:0048333]; multicellular organism growth [GO:0035264]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; notochord morphogenesis [GO:0048570]; positive regulation of cell size [GO:0045793]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression [GO:0010468]; respiratory system process [GO:0003016]; somite rostral/caudal axis specification [GO:0032525] GO:0000978; GO:0001701; GO:0001843; GO:0003007; GO:0003016; GO:0005634; GO:0005654; GO:0006338; GO:0007507; GO:0010468; GO:0010628; GO:0021915; GO:0031490; GO:0032525; GO:0035097; GO:0035264; GO:0042802; GO:0044666; GO:0045793; GO:0045944; GO:0046872; GO:0048333; GO:0048568; GO:0048570; GO:0071305; GO:0071557; GO:0071558; GO:0072359; GO:1903298; GO:1990841 11844 XM_029346001.2 1101 583 425 790 905 O70546 1.99e-132 Lysine-specific demethylase 6A (EC 1.14.11.68) (Histone demethylase UTX) (Ubiquitously transcribed TPR protein on the X chromosome) (Ubiquitously transcribed X chromosome tetratricopeptide repeat protein) ([histone H3]-trimethyl-L-lysine(27) demethylase 6A) Mus musculus (Mouse) cellular response to vitamin D [GO:0071305]; chromatin remodeling [GO:0006338]; circulatory system development [GO:0072359]; embryonic organ development [GO:0048568]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; histone H3-K27 demethylation [GO:0071557]; in utero embryonic development [GO:0001701]; mesodermal cell differentiation [GO:0048333]; multicellular organism growth [GO:0035264]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; notochord morphogenesis [GO:0048570]; positive regulation of cell size [GO:0045793]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression [GO:0010468]; respiratory system process [GO:0003016]; somite rostral/caudal axis specification [GO:0032525] GO:0000978; GO:0001701; GO:0001843; GO:0003007; GO:0003016; GO:0005634; GO:0005654; GO:0006338; GO:0007507; GO:0010468; GO:0010628; GO:0021915; GO:0031490; GO:0032525; GO:0035097; GO:0035264; GO:0042802; GO:0044666; GO:0045793; GO:0045944; GO:0046872; GO:0048333; GO:0048568; GO:0048570; GO:0071305; GO:0071557; GO:0071558; GO:0072359; GO:1903298; GO:1990841 11845 XM_029349011.2 648 584 447 961 850 NA NA NA NA NA NA 11846 XM_044329271.1 2042 1555 1527 2857 2355 NA NA NA NA NA NA 11847 XR_003826421.2 0 0 0 10 0 NA NA NA NA NA NA 11848 XM_044318723.1 271 93 109 229 34 NA NA NA NA NA NA 11849 XM_029358694.2 0 0 0 81 196 Q99L13 7.44e-124 3-hydroxyisobutyrate dehydrogenase, mitochondrial (HIBADH) (EC 1.1.1.31) Mus musculus (Mouse) valine catabolic process [GO:0006574] GO:0005739; GO:0006574; GO:0008442; GO:0016616; GO:0050661; GO:0051287 11850 XM_044306984.1 316 232 241 607 470 Q8IZC6 9.15e-35 Collagen alpha-1(XXVII) chain Homo sapiens (Human) extracellular matrix organization [GO:0030198]; growth plate cartilage chondrocyte development [GO:0003431] GO:0003431; GO:0005201; GO:0005576; GO:0005583; GO:0005615; GO:0005788; GO:0030020; GO:0030198; GO:0031012; GO:0046872; GO:0062023 11851 XR_006395672.1 537 283 105 45 29 NA NA NA NA NA NA 11852 XM_029330229.2 222 119 84 48 166 O18870 1.55e-22 Survival motor neuron protein Bos taurus (Bovine) DNA-templated transcription termination [GO:0006353]; nervous system development [GO:0007399]; spliceosomal snRNP assembly [GO:0000387] GO:0000387; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006353; GO:0007399; GO:0015030; GO:0030018; GO:0030424; GO:0032797; GO:0034719; GO:0036464; GO:0043005; GO:0043204; GO:0097504 11853 XM_029343341.2 4343 3699 2022 3576 2722 NA NA NA NA NA NA 11854 XM_029349846.2 194 738 442 780 443 NA NA NA NA NA NA 11855 XM_044325856.1 0 12 0 0 0 NA NA NA NA NA NA 11856 XR_003827213.1 6 22 2 26 16 NA NA NA NA NA NA 11857 XR_006395279.1 145 101 48 82 165 NA NA NA NA NA NA 11858 XM_029335935.2 30 16 25 44 111 NA NA NA NA NA NA 11859 XM_029357010.2 90 37 108 108 94 Q99829 7.06e-84 Copine-1 (Chromobindin 17) (Copine I) Homo sapiens (Human) cellular response to calcium ion [GO:0071277]; lipid metabolic process [GO:0006629]; negative regulation of DNA binding [GO:0043392]; negative regulation of gene expression [GO:0010629]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; neuron projection extension [GO:1990138]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; proteolysis [GO:0006508]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; vesicle-mediated transport [GO:0016192] GO:0001786; GO:0004175; GO:0005509; GO:0005544; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0006508; GO:0006629; GO:0010629; GO:0016020; GO:0016192; GO:0016235; GO:0031965; GO:0035577; GO:0042802; GO:0043122; GO:0043392; GO:0045666; GO:0051059; GO:0051897; GO:0070062; GO:0071277; GO:1901223; GO:1903265; GO:1990138 11860 XR_006393095.1 23 1 0 15 31 NA NA NA NA NA NA 11861 XM_044307367.1 692 0 699 345 123 P20072 5.04e-70 Annexin A7 (Annexin VII) (Annexin-7) (Synexin) Bos taurus (Bovine) NA GO:0005509; GO:0005544; GO:0005634; GO:0005737; GO:0042584 11862 XM_029347385.2 0 11 1 4 10 NA NA NA NA NA NA 11863 XM_029347903.2 420 876 507 1051 152 NA NA NA NA NA NA 11864 XM_044326804.1 0 32 0 91 0 NA NA NA NA NA NA 11865 XM_029329759.2 446 258 301 225 279 A0A0G2L7I0 4.02e-115 DNA-dependent metalloprotease SPRTN (EC 3.4.24.-) (Protein with SprT-like domain at the N terminus) (Spartan) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to DNA damage stimulus [GO:0006974]; protein autoprocessing [GO:0016540]; protein-DNA covalent cross-linking repair [GO:0106300]; proteolysis [GO:0006508] GO:0000785; GO:0003690; GO:0003697; GO:0004222; GO:0005634; GO:0006508; GO:0006974; GO:0016540; GO:0031593; GO:0046872; GO:0106300 11866 XM_029334502.2 1162 580 468 775 701 NA NA NA NA NA NA 11867 XR_006393794.1 29 34 56 30 35 NA NA NA NA NA NA 11868 XM_044320029.1 27 108 0 134 385 Q640F2 9.93e-59 SHC SH2 domain-binding protein 1 homolog B Xenopus laevis (African clawed frog) fibroblast growth factor receptor signaling pathway [GO:0008543]; regulation of neural precursor cell proliferation [GO:2000177] GO:0005737; GO:0005819; GO:0008543; GO:0030496; GO:2000177 11869 XM_044311292.1 12 15 25 7 17 P83852 3.02e-120 Carboxypeptidase D (EC 3.4.17.22) (CPD-2) (Metallocarboxypeptidase D) Lophonetta specularioides (Crested duck) (Anas specularioides) proteolysis [GO:0006508] GO:0004181; GO:0006508; GO:0008270; GO:0016020 11870 XM_044317112.1 0 0 1 8 0 NA NA NA NA NA NA 11871 XR_006396646.1 153 525 337 70 392 NA NA NA NA NA NA 11872 XM_044319028.1 3 16 7 24 0 Q9UHC6 6.39e-38 Contactin-associated protein-like 2 (Cell recognition molecule Caspr2) Homo sapiens (Human) adult behavior [GO:0030534]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell population proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; clustering of voltage-gated potassium channels [GO:0045163]; learning [GO:0007612]; limbic system development [GO:0021761]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuron recognition [GO:0008038]; positive regulation of gap junction assembly [GO:1903598]; protein localization to juxtaparanode region of axon [GO:0071205]; social behavior [GO:0035176]; striatum development [GO:0021756]; superior temporal gyrus development [GO:0071109]; thalamus development [GO:0021794]; transmission of nerve impulse [GO:0019226]; vocal learning [GO:0042297]; vocalization behavior [GO:0071625] GO:0005769; GO:0005794; GO:0007155; GO:0007420; GO:0007612; GO:0008038; GO:0008076; GO:0008283; GO:0009986; GO:0016020; GO:0019226; GO:0019899; GO:0021756; GO:0021761; GO:0021794; GO:0021987; GO:0030424; GO:0030425; GO:0030534; GO:0030673; GO:0031175; GO:0033010; GO:0035176; GO:0042297; GO:0043025; GO:0043204; GO:0044224; GO:0045163; GO:0048812; GO:0071109; GO:0071205; GO:0071625; GO:1903598 11873 XR_006392304.1 0 4 6 14 10 NA NA NA NA NA NA 11874 XM_029351329.2 1391 1285 802 1117 1324 Q9Z1N0 0 Peroxisomal acyl-coenzyme A oxidase 1 (AOX) (EC 1.3.3.6) (Palmitoyl-CoA oxidase) (Peroxisomal fatty acyl-CoA oxidase) (Straight-chain acyl-CoA oxidase) [Cleaved into: Peroxisomal acyl-CoA oxidase 1, A chain; Peroxisomal acyl-CoA oxidase 1, B chain; Peroxisomal acyl-CoA oxidase 1, C chain] Cavia porcellus (Guinea pig) fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; fatty acid oxidation [GO:0019395]; generation of precursor metabolites and energy [GO:0006091]; lipid metabolic process [GO:0006629]; prostaglandin metabolic process [GO:0006693] GO:0003997; GO:0005504; GO:0005777; GO:0006091; GO:0006629; GO:0006693; GO:0019395; GO:0033540; GO:0071949 11875 XM_029339013.2 1612 912 1163 1627 2391 Q32LQ4 0 Betaine--homocysteine S-methyltransferase 1 (EC 2.1.1.5) Danio rerio (Zebrafish) (Brachydanio rerio) amino-acid betaine catabolic process [GO:0006579]; digestive system development [GO:0055123]; L-methionine salvage [GO:0071267]; methionine biosynthetic process [GO:0009086]; methylation [GO:0032259]; type B pancreatic cell development [GO:0003323] GO:0003323; GO:0005829; GO:0006579; GO:0008270; GO:0009086; GO:0032259; GO:0047150; GO:0055123; GO:0071267 11876 XM_044323790.1 31 0 65 0 0 NA NA NA NA NA NA 11877 XM_044317163.1 37 0 0 0 0 P29119 6.57e-119 Furin-1 (EC 3.4.21.75) (Dibasic-processing enzyme) (Paired basic amino acid residue-cleaving enzyme) (PACE) Xenopus laevis (African clawed frog) positive regulation of transforming growth factor beta1 activation [GO:1901394]; proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0005794; GO:0005886; GO:0006508; GO:0010008; GO:0046872; GO:1901394 11878 XM_044308745.1 448 0 0 0 0 NA NA NA NA NA NA 11879 XM_044322488.1 249 36 21 0 28 NA NA NA NA NA NA 11880 XM_029342851.2 9 1 1 11 7 NA NA NA NA NA NA 11881 XR_006394287.1 92 37 106 109 111 NA NA NA NA NA NA 11882 XM_029338124.2 174 58 38 116 239 P08510 1.74e-87 Potassium voltage-gated channel protein Shaker (Protein minisleep) Drosophila melanogaster (Fruit fly) action potential [GO:0001508]; axon extension [GO:0048675]; behavioral response to ether [GO:0048150]; cellular response to dopamine [GO:1903351]; courtship behavior [GO:0007619]; detection of visible light [GO:0009584]; larval locomotory behavior [GO:0008345]; learning or memory [GO:0007611]; mating behavior, sex discrimination [GO:0048047]; positive regulation of circadian sleep/wake cycle, sleep [GO:0045938]; positive regulation of membrane potential [GO:0045838]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; proboscis extension reflex [GO:0007637]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; regulation of ion transmembrane transport [GO:0034765]; regulation of synaptic activity [GO:0060025]; sensory perception of taste [GO:0050909]; sleep [GO:0030431] GO:0001508; GO:0005249; GO:0005251; GO:0006813; GO:0007611; GO:0007619; GO:0007637; GO:0008076; GO:0008345; GO:0009584; GO:0016020; GO:0022843; GO:0030431; GO:0034765; GO:0045187; GO:0045838; GO:0045938; GO:0048047; GO:0048150; GO:0048675; GO:0050909; GO:0051260; GO:0060025; GO:0071805; GO:1903351 11883 XM_029339084.2 431 346 322 404 936 Q5T2R2 6.98e-125 All trans-polyprenyl-diphosphate synthase PDSS1 (All-trans-decaprenyl-diphosphate synthase subunit 1) (EC 2.5.1.91) (Decaprenyl pyrophosphate synthase subunit 1) (Decaprenyl-diphosphate synthase subunit 1) (Solanesyl-diphosphate synthase subunit 1) (Trans-prenyltransferase 1) (TPT 1) Homo sapiens (Human) isoprenoid biosynthetic process [GO:0008299]; ubiquinone biosynthetic process [GO:0006744] GO:0000010; GO:0004659; GO:0005759; GO:0006744; GO:0008299; GO:0046872; GO:0046982; GO:0052923; GO:0097269; GO:1990234 11884 XM_029329948.2 147 0 151 195 156 Q16445 7.48e-58 Gamma-aminobutyric acid receptor subunit alpha-6 (GABA(A) receptor subunit alpha-6) Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid signaling pathway [GO:0007214]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; regulation of postsynaptic membrane potential [GO:0060078]; signal transduction [GO:0007165]; synaptic transmission, GABAergic [GO:0051932] GO:0004890; GO:0005231; GO:0005237; GO:0005886; GO:0007165; GO:0007214; GO:0007268; GO:0008503; GO:0022851; GO:0030594; GO:0032590; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051932; GO:0060078; GO:0098794; GO:0099192; GO:1902476; GO:1902711; GO:1904315 11885 XM_029349200.2 918 1094 648 1819 1348 O95847 4.02e-127 Mitochondrial uncoupling protein 4 (UCP 4) (Solute carrier family 25 member 27) Homo sapiens (Human) response to cold [GO:0009409] GO:0005739; GO:0005743; GO:0009409; GO:0022857; GO:0031966 11886 XM_029328555.2 3672 5138 1523 5303 2208 Q8BUB6 3.71e-52 Uronyl 2-sulfotransferase (EC 2.8.2.-) Mus musculus (Mouse) establishment of cell polarity [GO:0030010]; regulation of axonogenesis [GO:0050770] GO:0000139; GO:0008146; GO:0030010; GO:0050770 11887 XM_029331255.2 926 1117 858 1211 483 Q9SMQ6 4.95e-47 Ras-related protein RABA4b (AtRABA4b) (Ras-related protein GB3) (AtGB3) (Ras-related protein Rab11G) (AtRab11G) Arabidopsis thaliana (Mouse-ear cress) cell wall biogenesis [GO:0042546]; endocytic recycling [GO:0032456]; protein transport [GO:0015031] GO:0003924; GO:0005525; GO:0005768; GO:0005794; GO:0005886; GO:0015031; GO:0019900; GO:0031901; GO:0032456; GO:0032588; GO:0035619; GO:0042546; GO:0090404 11888 XM_029331395.2 896 845 546 740 811 Q53FA7 1.4e-97 Quinone oxidoreductase PIG3 (EC 1.6.5.5) (NADPH:quinone reductase PIG3) (Tumor protein p53-inducible protein 3) (Protein PIG3) (p53-induced gene 3 protein) Homo sapiens (Human) NADP metabolic process [GO:0006739] GO:0003960; GO:0005829; GO:0006739; GO:0016651; GO:0042803; GO:0048038; GO:0070402 11889 XM_029332272.2 531 176 228 88 355 A5A779 1.01e-148 Geranylgeranyl transferase type-2 subunit alpha (EC 2.5.1.60) (Geranylgeranyl transferase type II subunit alpha) (Rab geranyl-geranyltransferase subunit alpha) (Rab GG transferase alpha) (Rab GGTase alpha) (Rab geranylgeranyltransferase subunit alpha) Sus scrofa (Pig) protein geranylgeranylation [GO:0018344] GO:0004663; GO:0005737; GO:0005968; GO:0008270; GO:0018344; GO:0031267 11890 XM_044311772.1 303 335 161 212 539 NA NA NA NA NA NA 11891 XM_044309903.1 343 228 399 203 300 NA NA NA NA NA NA 11892 XR_003824588.2 83 150 91 681 96 NA NA NA NA NA NA 11893 XM_029337414.2 269 264 306 495 250 Q9MYM7 1.38e-26 Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.86) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1) Pongo pygmaeus (Bornean orangutan) lipid metabolic process [GO:0006629]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0006629; GO:0047275 11894 XM_044322708.1 21 4 14 23 5 NA NA NA NA NA NA 11895 XM_044326506.1 2211 1365 917 2022 1391 Q96I99 7.29e-169 Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial (EC 6.2.1.4) (GTP-specific succinyl-CoA synthetase subunit beta) (G-SCS) (GTPSCS) (Succinyl-CoA synthetase beta-G chain) (SCS-betaG) Homo sapiens (Human) succinyl-CoA catabolic process [GO:1901289]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099] GO:0000287; GO:0004776; GO:0005524; GO:0005525; GO:0005739; GO:0005759; GO:0005886; GO:0006099; GO:0006104; GO:0042709; GO:0045244; GO:1901289 11896 XM_044327014.1 0 17 16 0 0 NA NA NA NA NA NA 11897 XM_029348075.2 2406 1929 1320 1611 1753 Q8CGS4 1.71e-80 Charged multivesicular body protein 3 (Chromatin-modifying protein 3) (Vacuolar protein sorting-associated protein 24) (rVps24p) Rattus norvegicus (Rat) autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; endosome to lysosome transport [GO:0008333]; endosome transport via multivesicular body sorting pathway [GO:0032509]; late endosome to lysosome transport [GO:1902774]; late endosome to vacuole transport [GO:0045324]; midbody abscission [GO:0061952]; mitotic metaphase plate congression [GO:0007080]; multivesicular body sorting pathway [GO:0071985]; multivesicular body-lysosome fusion [GO:0061763]; negative regulation of cell death [GO:0060548]; nuclear membrane reassembly [GO:0031468]; nucleus organization [GO:0006997]; plasma membrane repair [GO:0001778]; positive regulation of cytokinesis [GO:0032467]; protein polymerization [GO:0051258]; protein transport [GO:0015031]; regulation of centrosome duplication [GO:0010824]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of endosome size [GO:0051036]; regulation of mitotic spindle assembly [GO:1901673]; suppression of viral release by host [GO:0044790]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; viral budding from plasma membrane [GO:0046761]; viral budding via host ESCRT complex [GO:0039702]; viral release from host cell [GO:0019076] GO:0000421; GO:0000776; GO:0000815; GO:0001778; GO:0005546; GO:0005643; GO:0005765; GO:0005769; GO:0005770; GO:0005771; GO:0005828; GO:0005829; GO:0005886; GO:0006914; GO:0006997; GO:0007080; GO:0008333; GO:0010824; GO:0015031; GO:0019076; GO:0030496; GO:0031210; GO:0031410; GO:0031468; GO:0032467; GO:0032509; GO:0032585; GO:0039702; GO:0043162; GO:0044790; GO:0045324; GO:0046761; GO:0051036; GO:0051258; GO:0060548; GO:0061763; GO:0061952; GO:0071985; GO:0097352; GO:0140678; GO:1901673; GO:1902774; GO:1904930; GO:1990381; GO:2000641 11898 XM_044324483.1 78 74 69 61 86 NA NA NA NA NA NA 11899 XM_029324651.2 14 35 17 2 20 NA NA NA NA NA NA 11900 XM_029356603.2 93 92 85 140 195 NA NA NA NA NA NA 11901 XM_029352294.2 830 265 323 599 614 Q3V2A7 4.11e-26 Glutamine-rich protein 2 Mus musculus (Mouse) cell projection assembly [GO:0030031]; flagellated sperm motility [GO:0030317]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059] GO:0005634; GO:0005737; GO:0030031; GO:0030317; GO:0031965; GO:0036126; GO:2000059 11902 XM_044327838.1 0 0 6 0 0 NA NA NA NA NA NA 11903 XR_006394611.1 34 12 29 0 9 NA NA NA NA NA NA 11904 XM_029354572.2 66 145 120 82 88 NA NA NA NA NA NA 11905 XM_029348592.2 0 93 16 84 0 Q9DEY9 5.33e-177 RecQ-like DNA helicase BLM (EC 3.6.4.12) (Bloom syndrome protein homolog) (xBLM) (RecQ helicase homolog) Xenopus laevis (African clawed frog) DNA double-strand break processing [GO:0000729]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA replication [GO:0006260]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of DNA-templated DNA replication [GO:0090329] GO:0000400; GO:0000729; GO:0003677; GO:0003678; GO:0003697; GO:0005524; GO:0005634; GO:0006260; GO:0006310; GO:0008094; GO:0008270; GO:0009378; GO:0016887; GO:0032508; GO:0042803; GO:0043138; GO:0051259; GO:0051260; GO:0061749; GO:0090329 11906 XM_044318836.1 90 138 1 46 259 Q91Z40 7.97e-46 Guanylate-binding protein 7 (EC 3.6.5.-) (GTP-binding protein 7) (GBP-7) (Guanine nucleotide-binding protein 7) (Guanylate-binding protein 4-like) Mus musculus (Mouse) adhesion of symbiont to host [GO:0044406]; cellular response to interferon-beta [GO:0035458]; cellular response to type II interferon [GO:0071346]; defense response to Gram-positive bacterium [GO:0050830]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; negative regulation of cytokine production [GO:0001818]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of type I interferon production [GO:0032480]; negative regulation of type III interferon production [GO:0034345]; positive regulation of viral genome replication [GO:0045070]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122] GO:0001818; GO:0003924; GO:0005525; GO:0016020; GO:0020005; GO:0031410; GO:0032480; GO:0034345; GO:0035458; GO:0042832; GO:0043122; GO:0044406; GO:0045070; GO:0046426; GO:0050830; GO:0051607; GO:0071346 11907 XR_006397698.1 202 84 0 207 238 NA NA NA NA NA NA 11908 XR_006393700.1 61 48 20 53 34 Q06AB3 4.51e-30 Ubiquitin carboxyl-terminal hydrolase isozyme L3 (UCH-L3) (EC 3.4.19.12) (Ubiquitin thioesterase L3) Sus scrofa (Pig) protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004843; GO:0005737; GO:0006511; GO:0016579 11909 XM_029333310.2 1408 825 767 1057 1089 A3KQS4 5.66e-113 Ubiquitin carboxyl-terminal hydrolase MINDY-1 (EC 3.4.19.12) (Deubiquitinating enzyme MINDY-1) (Protein FAM63A) Danio rerio (Zebrafish) (Brachydanio rerio) proteolysis [GO:0006508] GO:0004843; GO:0006508; GO:0036435; GO:1990380 11910 XM_044320861.1 503 227 346 162 559 NA NA NA NA NA NA 11911 XM_029343577.2 35 407 0 293 682 P47862 1.2e-82 Aquaporin-3 (AQP-3) (31.4 kDa water channel protein) (Aquaglyceroporin-3) Rattus norvegicus (Rat) cellular response to hypoxia [GO:0071456]; cellular response to oxygen-glucose deprivation [GO:0090650]; establishment of localization in cell [GO:0051649]; glycerol transmembrane transport [GO:0015793]; odontogenesis [GO:0042476]; polyol transmembrane transport [GO:0015791]; positive regulation of immune system process [GO:0002684]; renal water absorption [GO:0070295]; response to retinoic acid [GO:0032526]; urea transport [GO:0015840]; water transport [GO:0006833] GO:0002684; GO:0005737; GO:0005886; GO:0005911; GO:0006833; GO:0015166; GO:0015204; GO:0015250; GO:0015254; GO:0015791; GO:0015793; GO:0015840; GO:0016323; GO:0032526; GO:0042476; GO:0042802; GO:0051649; GO:0070295; GO:0071456; GO:0090650 11912 XM_029348723.2 0 0 0 15 15 B0UY98 2.07e-22 NA NA NA NA 11913 XR_006393339.1 54 41 49 6 77 NA NA NA NA NA NA 11914 XM_044311975.1 0 37 0 0 0 NA NA NA NA NA NA 11915 XM_029352112.2 1335 760 727 1341 933 Q9CZV8 4.84e-171 F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like) Mus musculus (Mouse) behavioral fear response [GO:0001662]; regulation of protein catabolic process at presynapse, modulating synaptic transmission [GO:0099575]; regulation of synaptic vesicle exocytosis [GO:2000300]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0001662; GO:0005737; GO:0019005; GO:0031146; GO:0045202; GO:0098685; GO:0098793; GO:0098978; GO:0099575; GO:2000300 11916 XM_029334600.2 928 929 828 878 943 Q61753 2.12e-153 D-3-phosphoglycerate dehydrogenase (3-PGDH) (EC 1.1.1.95) (A10) Mus musculus (Mouse) G1 to G0 transition [GO:0070314]; gamma-aminobutyric acid metabolic process [GO:0009448]; glial cell development [GO:0021782]; glutamine metabolic process [GO:0006541]; glycine metabolic process [GO:0006544]; L-serine biosynthetic process [GO:0006564]; L-serine metabolic process [GO:0006563]; neural tube development [GO:0021915]; neurogenesis [GO:0022008]; neuron projection development [GO:0031175]; regulation of gene expression [GO:0010468]; spinal cord development [GO:0021510]; taurine metabolic process [GO:0019530]; threonine metabolic process [GO:0006566] GO:0004617; GO:0006541; GO:0006544; GO:0006563; GO:0006564; GO:0006566; GO:0009448; GO:0010468; GO:0019530; GO:0021510; GO:0021782; GO:0021915; GO:0022008; GO:0031175; GO:0043209; GO:0051287; GO:0070314 11917 XM_029336307.2 231 1005 0 0 714 NA NA NA NA NA NA 11918 XM_029342226.2 0 0 29 0 0 NA NA NA NA NA NA 11919 XM_029343326.2 2825 1108 49 1009 0 O97562 4.44e-113 Dicarboxylate carrier SLC25A8 (Mitochondrial uncoupling protein 2) (UCP 2) (Solute carrier family 25 member 8) Sus scrofa (Pig) adaptive thermogenesis [GO:1990845]; C4-dicarboxylate transport [GO:0015740]; cellular response to glucose stimulus [GO:0071333]; glutamine metabolic process [GO:0006541]; glycolytic process [GO:0006096]; macrophage differentiation [GO:0030225]; mitochondrial fission [GO:0000266]; mitochondrial transmembrane transport [GO:1990542]; mitochondrial transport [GO:0006839]; reactive oxygen species metabolic process [GO:0072593]; response to cold [GO:0009409] GO:0000266; GO:0005743; GO:0006096; GO:0006541; GO:0006839; GO:0008271; GO:0009409; GO:0015078; GO:0015131; GO:0015140; GO:0015183; GO:0015297; GO:0015740; GO:0017077; GO:0022857; GO:0030225; GO:0042803; GO:0071333; GO:0072593; GO:0140787; GO:1990542; GO:1990845 11920 XR_006394433.1 0 0 23 73 104 NA NA NA NA NA NA 11921 XM_029351408.2 1291 1249 898 1371 1283 Q5RCF3 0 Cullin-2 (CUL-2) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0005634; GO:0006511; GO:0016567; GO:0031461; GO:0031625 11922 XM_029346404.2 270 296 167 218 155 Q9SY73 1.4e-61 NADPH-dependent pterin aldehyde reductase (EC 1.1.1.-) Arabidopsis thaliana (Mouse-ear cress) folic acid-containing compound metabolic process [GO:0006760] GO:0005829; GO:0006760; GO:0016616 11923 XM_029345753.2 0 0 23 0 99 Q91035 1.17e-93 Sonic hedgehog protein (SHH) (EC 3.1.-.-) (Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains) (ShhNC) [Cleaved into: Sonic hedgehog protein N-product (ShhN) (Shh N-terminal processed signaling domains) (ShhNp)] Gallus gallus (Chicken) anterior/posterior pattern specification [GO:0009952]; apoptotic signaling pathway [GO:0097190]; cell fate determination [GO:0001709]; cell fate specification involved in pattern specification [GO:0060573]; cell-cell signaling [GO:0007267]; chondroblast differentiation [GO:0060591]; commissural neuron axon guidance [GO:0071679]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; fibroblast growth factor production [GO:0090269]; floor plate formation [GO:0021508]; growth plate cartilage chondrocyte growth [GO:0003430]; homeostasis of number of retina cells [GO:0048877]; intein-mediated protein splicing [GO:0016539]; negative regulation of apoptotic process [GO:0043066]; negative regulation of BMP signaling pathway [GO:0030514]; optic cup formation involved in camera-type eye development [GO:0003408]; optic nerve morphogenesis [GO:0021631]; polarity specification of anterior/posterior axis [GO:0009949]; polarity specification of dorsal/ventral axis [GO:0009951]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of cell morphogenesis involved in differentiation [GO:0010770]; positive regulation of gene expression [GO:0010628]; positive regulation of neural retina development [GO:0061075]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of smoothened signaling pathway [GO:0045880]; protein autoprocessing [GO:0016540]; proteoglycan biosynthetic process [GO:0030166]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; regulation of cell differentiation involved in tissue homeostasis [GO:0060786]; regulation of gene expression [GO:0010468]; regulation of neural precursor cell proliferation [GO:2000177]; response to retinoic acid [GO:0032526]; retina homeostasis [GO:0001895]; retinal pigment epithelium development [GO:0003406]; self proteolysis [GO:0097264]; signaling [GO:0023052]; spinal cord dorsal/ventral patterning [GO:0021513]; tissue development [GO:0009888] GO:0000139; GO:0001709; GO:0001895; GO:0003406; GO:0003408; GO:0003430; GO:0005509; GO:0005576; GO:0005615; GO:0005783; GO:0005789; GO:0005794; GO:0005886; GO:0007267; GO:0008233; GO:0008270; GO:0009880; GO:0009888; GO:0009949; GO:0009951; GO:0009952; GO:0010468; GO:0010628; GO:0010694; GO:0010770; GO:0016015; GO:0016539; GO:0016540; GO:0021508; GO:0021513; GO:0021631; GO:0023052; GO:0030166; GO:0030326; GO:0030514; GO:0032526; GO:0042733; GO:0043066; GO:0045669; GO:0045880; GO:0048877; GO:0060059; GO:0060573; GO:0060591; GO:0060785; GO:0060786; GO:0061075; GO:0071679; GO:0090269; GO:0097190; GO:0097264; GO:0140853; GO:2000177 11924 XM_044315395.1 6 1 1 16 26 B8VIU6 5.25e-38 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 11925 XM_044312659.1 45 264 58 146 166 NA NA NA NA NA NA 11926 XM_029333163.2 1850 2146 921 1710 991 Q5XIF3 1.34e-54 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (Complex I-18 kDa) (CI-18 kDa) (NADH-ubiquinone oxidoreductase 18 kDa subunit) Rattus norvegicus (Rat) adult behavior [GO:0030534]; adult walking behavior [GO:0007628]; brain development [GO:0007420]; cellular respiration [GO:0045333]; cellular response to oxygen levels [GO:0071453]; cognition [GO:0050890]; dopamine metabolic process [GO:0042417]; electron transport chain [GO:0022900]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; mitochondrial respiratory chain complex I assembly [GO:0032981]; neuron death [GO:0070997]; positive regulation of fibroblast proliferation [GO:0048146]; psychomotor behavior [GO:0036343]; reactive oxygen species metabolic process [GO:0072593]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of protein phosphorylation [GO:0001932]; respiratory electron transport chain [GO:0022904]; respiratory system process [GO:0003016]; response to cAMP [GO:0051591]; response to injury involved in regulation of muscle adaptation [GO:0014876]; sensory perception of sound [GO:0007605]; transmembrane transport [GO:0055085]; visual perception [GO:0007601] GO:0001932; GO:0003016; GO:0005739; GO:0005743; GO:0005747; GO:0006954; GO:0007420; GO:0007601; GO:0007605; GO:0007628; GO:0008137; GO:0014876; GO:0022900; GO:0022904; GO:0030534; GO:0032981; GO:0036343; GO:0042417; GO:0045087; GO:0045333; GO:0048146; GO:0050890; GO:0051591; GO:0051881; GO:0055085; GO:0070997; GO:0071453; GO:0072593 11927 XM_044327906.1 21 0 0 27 0 NA NA NA NA NA NA 11928 XM_029347832.2 165 61 85 124 237 NA NA NA NA NA NA 11929 XM_029342204.2 1522 924 710 1238 1519 Q6KC79 0 Nipped-B-like protein (Delangin) (SCC2 homolog) Homo sapiens (Human) brain development [GO:0007420]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to X-ray [GO:0071481]; cognition [GO:0050890]; developmental growth [GO:0048589]; digestive tract development [GO:0048565]; ear morphogenesis [GO:0042471]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic forelimb morphogenesis [GO:0035115]; embryonic viscerocranium morphogenesis [GO:0048703]; establishment of mitotic sister chromatid cohesion [GO:0034087]; establishment of protein localization to chromatin [GO:0071169]; external genitalia morphogenesis [GO:0035261]; eye morphogenesis [GO:0048592]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forelimb morphogenesis [GO:0035136]; gallbladder development [GO:0061010]; heart morphogenesis [GO:0003007]; maintenance of mitotic sister chromatid cohesion [GO:0034088]; metanephros development [GO:0001656]; mitotic cohesin loading [GO:0061780]; mitotic sister chromatid cohesion [GO:0007064]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; outflow tract morphogenesis [GO:0003151]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of neuron migration [GO:2001224]; positive regulation of ossification [GO:0045778]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization [GO:0008104]; regulation of developmental growth [GO:0048638]; regulation of embryonic development [GO:0045995]; regulation of hair cycle [GO:0042634]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414]; sensory perception of sound [GO:0007605]; somatic stem cell population maintenance [GO:0035019]; uterus morphogenesis [GO:0061038] GO:0000122; GO:0000785; GO:0001656; GO:0003007; GO:0003151; GO:0003682; GO:0005634; GO:0005654; GO:0005829; GO:0006974; GO:0007064; GO:0007420; GO:0007605; GO:0008022; GO:0008104; GO:0031065; GO:0032039; GO:0032116; GO:0034087; GO:0034088; GO:0035019; GO:0035115; GO:0035136; GO:0035261; GO:0036033; GO:0040018; GO:0042471; GO:0042634; GO:0042826; GO:0043231; GO:0045444; GO:0045778; GO:0045892; GO:0045944; GO:0045995; GO:0047485; GO:0048557; GO:0048565; GO:0048589; GO:0048592; GO:0048638; GO:0048703; GO:0050890; GO:0060325; GO:0061010; GO:0061038; GO:0061775; GO:0061780; GO:0070062; GO:0070087; GO:0071169; GO:0071481; GO:0090694; GO:1990414; GO:1990841; GO:2001224 11930 XM_044319967.1 0 46 8 129 4 NA NA NA NA NA NA 11931 XM_029338620.2 367 251 296 495 597 P21521 1.59e-123 Synaptotagmin 1 (p65) Drosophila melanogaster (Fruit fly) calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; chemical synaptic transmission [GO:0007268]; clathrin-dependent synaptic vesicle endocytosis [GO:0150007]; larval locomotory behavior [GO:0008345]; neurotransmitter secretion [GO:0007269]; positive regulation of vesicle fusion [GO:0031340]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of neuromuscular synaptic transmission [GO:1900073]; regulation of pole plasm oskar mRNA localization [GO:0007317]; regulation of synapse structure or activity [GO:0050803]; rhythmic synaptic transmission [GO:0060024]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle exocytosis [GO:0016079]; vesicle-mediated transport [GO:0016192] GO:0000149; GO:0001786; GO:0005509; GO:0005544; GO:0005886; GO:0007268; GO:0007269; GO:0007317; GO:0008021; GO:0008345; GO:0014059; GO:0016020; GO:0016079; GO:0016192; GO:0017156; GO:0017158; GO:0019905; GO:0030276; GO:0030424; GO:0030672; GO:0031045; GO:0031340; GO:0031594; GO:0042803; GO:0043195; GO:0048488; GO:0048791; GO:0050803; GO:0060024; GO:0070382; GO:0071277; GO:0150007; GO:1900073 11932 XM_029342100.2 180 148 81 99 124 Q8BGF9 2.13e-72 Solute carrier family 25 member 44 Mus musculus (Mouse) branched-chain amino acid catabolic process [GO:0009083]; branched-chain amino acid transport [GO:0015803]; regulation of cold-induced thermogenesis [GO:0120161] GO:0005739; GO:0005743; GO:0009083; GO:0015658; GO:0015803; GO:0120161 11933 XR_006391594.1 30 10 0 53 17 O89000 9.33e-23 Dihydropyrimidine dehydrogenase [NADP(+)] (DHPDHase) (DPD) (EC 1.3.1.2) (Dihydrothymine dehydrogenase) (Dihydrouracil dehydrogenase) Rattus norvegicus (Rat) aging [GO:0007568]; beta-alanine biosynthetic process [GO:0019483]; circadian rhythm [GO:0007623]; CMP catabolic process [GO:0006248]; dCMP catabolic process [GO:0006249]; dUMP catabolic process [GO:0046079]; purine nucleobase catabolic process [GO:0006145]; pyrimidine nucleobase catabolic process [GO:0006208]; response to glucocorticoid [GO:0051384]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]; response to xenobiotic stimulus [GO:0009410]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; UMP catabolic process [GO:0046050]; uracil catabolic process [GO:0006212]; uracil metabolic process [GO:0019860] GO:0002058; GO:0005506; GO:0005737; GO:0005829; GO:0006145; GO:0006208; GO:0006210; GO:0006212; GO:0006214; GO:0006248; GO:0006249; GO:0007568; GO:0007584; GO:0007623; GO:0009410; GO:0014070; GO:0017113; GO:0019483; GO:0019860; GO:0042802; GO:0042803; GO:0046050; GO:0046079; GO:0050661; GO:0051384; GO:0051536; GO:0051539; GO:0071949 11934 XR_006391594.1 30 10 0 53 17 O89000 9.33e-23 Dihydropyrimidine dehydrogenase [NADP(+)] (DHPDHase) (DPD) (EC 1.3.1.2) (Dihydrothymine dehydrogenase) (Dihydrouracil dehydrogenase) Rattus norvegicus (Rat) aging [GO:0007568]; beta-alanine biosynthetic process [GO:0019483]; circadian rhythm [GO:0007623]; CMP catabolic process [GO:0006248]; dCMP catabolic process [GO:0006249]; dUMP catabolic process [GO:0046079]; purine nucleobase catabolic process [GO:0006145]; pyrimidine nucleobase catabolic process [GO:0006208]; response to glucocorticoid [GO:0051384]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]; response to xenobiotic stimulus [GO:0009410]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; UMP catabolic process [GO:0046050]; uracil catabolic process [GO:0006212]; uracil metabolic process [GO:0019860] GO:0002058; GO:0005506; GO:0005737; GO:0005829; GO:0006145; GO:0006208; GO:0006210; GO:0006212; GO:0006214; GO:0006248; GO:0006249; GO:0007568; GO:0007584; GO:0007623; GO:0009410; GO:0014070; GO:0017113; GO:0019483; GO:0019860; GO:0042802; GO:0042803; GO:0046050; GO:0046079; GO:0050661; GO:0051384; GO:0051536; GO:0051539; GO:0071949 11935 XM_044309788.1 1 0 1 12 11 NA NA NA NA NA NA 11936 XM_029337965.2 1025 703 449 809 668 O94966 1.47e-118 Ubiquitin carboxyl-terminal hydrolase 19 (EC 3.4.19.12) (Deubiquitinating enzyme 19) (Ubiquitin thioesterase 19) (Ubiquitin-specific-processing protease 19) (Zinc finger MYND domain-containing protein 9) Homo sapiens (Human) negative regulation of skeletal muscle tissue development [GO:0048642]; positive regulation of cell cycle process [GO:0090068]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of cellular response to hypoxia [GO:1900037]; regulation of ERAD pathway [GO:1904292]; regulation of protein stability [GO:0031647]; response to endoplasmic reticulum stress [GO:0034976]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0004843; GO:0005789; GO:0005829; GO:0016579; GO:0030433; GO:0031647; GO:0034976; GO:0046872; GO:0048642; GO:0050821; GO:0051879; GO:0090068; GO:1900037; GO:1904292 11937 XM_029337965.2 1025 703 449 809 668 O94966 4.98e-55 Ubiquitin carboxyl-terminal hydrolase 19 (EC 3.4.19.12) (Deubiquitinating enzyme 19) (Ubiquitin thioesterase 19) (Ubiquitin-specific-processing protease 19) (Zinc finger MYND domain-containing protein 9) Homo sapiens (Human) negative regulation of skeletal muscle tissue development [GO:0048642]; positive regulation of cell cycle process [GO:0090068]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of cellular response to hypoxia [GO:1900037]; regulation of ERAD pathway [GO:1904292]; regulation of protein stability [GO:0031647]; response to endoplasmic reticulum stress [GO:0034976]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0004843; GO:0005789; GO:0005829; GO:0016579; GO:0030433; GO:0031647; GO:0034976; GO:0046872; GO:0048642; GO:0050821; GO:0051879; GO:0090068; GO:1900037; GO:1904292 11938 XM_029356331.2 45 31 6 17 12 NA NA NA NA NA NA 11939 XM_029343931.2 1799 738 835 1035 968 NA NA NA NA NA NA 11940 XM_044307458.1 14 1 37 7 27 NA NA NA NA NA NA 11941 XM_029328532.2 732 1182 569 1245 557 P68372 0 Tubulin beta-4B chain (Tubulin beta-2C chain) Mus musculus (Mouse) microtubule cytoskeleton organization [GO:0000226]; microtubule-based process [GO:0007017]; mitotic cell cycle [GO:0000278] GO:0000226; GO:0000278; GO:0003725; GO:0003924; GO:0005200; GO:0005525; GO:0005737; GO:0005874; GO:0007017; GO:0015630; GO:0043209; GO:0045171; GO:0045298; GO:0046872; GO:0072686 11942 XM_044314734.1 0 0 0 2 13 Q09575 4.74e-23 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 11943 XM_044323322.1 230 15 307 351 745 Q6P5F6 2.02e-43 Zinc transporter ZIP10 (Solute carrier family 39 member 10) (Zrt- and Irt-like protein 10) (ZIP-10) Mus musculus (Mouse) cellular zinc ion homeostasis [GO:0006882]; negative regulation of B cell apoptotic process [GO:0002903]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of B cell receptor signaling pathway [GO:0050861]; positive regulation of protein tyrosine phosphatase activity [GO:1903615]; zinc ion import across plasma membrane [GO:0071578] GO:0002903; GO:0005385; GO:0005886; GO:0006882; GO:0030890; GO:0050861; GO:0071578; GO:1903615 11944 XR_006397005.1 17 0 5 3 14 NA NA NA NA NA NA 11945 XM_029339180.2 191 219 122 173 151 Q8U3Y2 1.38e-78 Glyoxylate reductase (EC 1.1.1.26) Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) NA GO:0005737; GO:0047964; GO:0051287 11946 XR_006392115.1 1 1 10 1 34 NA NA NA NA NA NA 11947 XM_044322016.1 111 7 106 49 0 NA NA NA NA NA NA 11948 XM_044324521.1 10 0 0 1 3 NA NA NA NA NA NA 11949 XR_003825337.2 1181 934 548 734 1063 NA NA NA NA NA NA 11950 XM_044309359.1 169 89 108 358 0 Q5UPX0 7.91e-30 Putative ATP-dependent RNA helicase R290 (EC 3.6.4.13) Acanthamoeba polyphaga mimivirus (APMV) DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260] GO:0003676; GO:0003724; GO:0005524; GO:0006260; GO:0006281; GO:0006310; GO:0016887; GO:0043138 11951 XM_044319207.1 323 230 152 164 54 P0DX22 2.02e-56 NA NA NA NA 11952 XM_044322304.1 8 0 0 1 2 NA NA NA NA NA NA 11953 XM_044324303.1 9423 214 1867 13856 10949 P49961 1.22e-48 Ectonucleoside triphosphate diphosphohydrolase 1 (NTPDase 1) (EC 3.6.1.5) (Ecto-ATP diphosphohydrolase 1) (Ecto-ATPDase 1) (Ecto-ATPase 1) (Ecto-apyrase) (Lymphoid cell activation antigen) (CD antigen CD39) Homo sapiens (Human) blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; nucleoside diphosphate catabolic process [GO:0009134] GO:0004382; GO:0005524; GO:0005886; GO:0007155; GO:0007596; GO:0009134; GO:0016020; GO:0017110; GO:0045134; GO:0070062 11954 XM_044326770.1 0 0 0 4 35 NA NA NA NA NA NA 11955 XM_044307573.1 0 0 8 11 0 P0DP43 5.2e-38 Cation channel sperm-associated auxiliary subunit epsilon (CatSper-epsilon) (CatSperepsilon) (C1orf101-like protein) Mus musculus (Mouse) flagellated sperm motility [GO:0030317]; sperm capacitation [GO:0048240] GO:0030317; GO:0036128; GO:0048240; GO:0097228 11956 XR_006395104.1 56 14 20 36 72 Q76KP1 3.75e-61 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Homo sapiens (Human) NA GO:0008376; GO:0032580; GO:0033842 11957 XR_006395104.1 56 14 20 36 72 Q76KP1 1.65e-27 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Homo sapiens (Human) NA GO:0008376; GO:0032580; GO:0033842 11958 XM_044316705.1 0 0 140 0 25 NA NA NA NA NA NA 11959 XR_006395437.1 65 15 66 46 0 NA NA NA NA NA NA 11960 XR_006395949.1 13 8 13 5 21 NA NA NA NA NA NA 11961 XR_006395907.1 4158 2951 1758 2920 1466 NA NA NA NA NA NA 11962 XM_044325237.1 32 35 57 130 45 Q66I21 0 2-aminomuconic semialdehyde dehydrogenase (EC 1.2.1.32) (Aldehyde dehydrogenase family 8 member A1) Danio rerio (Zebrafish) (Brachydanio rerio) L-kynurenine catabolic process [GO:0097053]; liver development [GO:0001889]; retinoic acid metabolic process [GO:0042573] GO:0001758; GO:0001889; GO:0005737; GO:0016620; GO:0042573; GO:0047102; GO:0097053 11963 XM_044326987.1 5 0 1 47 28 NA NA NA NA NA NA 11964 XM_029356821.2 155 129 150 201 175 Q6P1B1 0 Xaa-Pro aminopeptidase 1 (EC 3.4.11.9) (Aminoacylproline aminopeptidase) (Cytosolic aminopeptidase P) (Soluble aminopeptidase P) (sAmp) (X-Pro aminopeptidase 1) (X-prolyl aminopeptidase 1, soluble) Mus musculus (Mouse) bradykinin catabolic process [GO:0010815]; proteolysis [GO:0006508] GO:0004177; GO:0005737; GO:0005829; GO:0006508; GO:0010815; GO:0030145; GO:0042803; GO:0070006 11965 XR_006396185.1 286 25 187 148 17 NA NA NA NA NA NA 11966 XM_044325584.1 171 193 239 427 311 NA NA NA NA NA NA 11967 XM_044326891.1 324 175 106 299 642 NA NA NA NA NA NA 11968 XM_029336562.2 0 15 29 0 18 Q29496 7.38e-97 Cytochrome P450 3A24 (EC 1.14.14.1) (CYPIIIA24) Ovis aries (Sheep) NA GO:0004497; GO:0005506; GO:0005789; GO:0020037; GO:0070330 11969 XM_029342066.2 18 7 52 56 43 P28047 1.11e-47 Protein Wnt-7b Mus musculus (Mouse) anatomical structure regression [GO:0060033]; angiogenesis [GO:0001525]; apoptotic process involved in blood vessel morphogenesis [GO:1902262]; canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; cell population proliferation [GO:0008283]; cell proliferation in forebrain [GO:0021846]; cellular oxygen homeostasis [GO:0032364]; central nervous system vasculogenesis [GO:0022009]; chemoattraction of dopaminergic neuron axon [GO:0036516]; chorio-allantoic fusion [GO:0060710]; developmental growth involved in morphogenesis [GO:0060560]; embryonic organ development [GO:0048568]; embryonic placenta morphogenesis [GO:0060669]; establishment or maintenance of polarity of embryonic epithelium [GO:0016332]; forebrain regionalization [GO:0021871]; homeostatic process [GO:0042592]; in utero embryonic development [GO:0001701]; inner medullary collecting duct development [GO:0072061]; lobar bronchus development [GO:0060482]; lung development [GO:0030324]; lung epithelium development [GO:0060428]; lung morphogenesis [GO:0060425]; lung-associated mesenchyme development [GO:0060484]; metanephric collecting duct development [GO:0072205]; metanephric epithelium development [GO:0072207]; metanephric loop of Henle development [GO:0072236]; metanephros morphogenesis [GO:0003338]; negative regulation of neurogenesis [GO:0050768]; negative regulation of smoothened signaling pathway [GO:0045879]; neuron differentiation [GO:0030182]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; odontogenesis of dentin-containing tooth [GO:0042475]; osteoblast differentiation [GO:0001649]; outer medullary collecting duct development [GO:0072060]; planar cell polarity pathway involved in axon guidance [GO:1904938]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of JNK cascade [GO:0046330]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell projection size [GO:0032536]; renal inner medulla development [GO:0072053]; renal outer medulla development [GO:0072054]; smooth muscle cell differentiation [GO:0051145]; stem cell development [GO:0048864]; synapse organization [GO:0050808]; trachea cartilage morphogenesis [GO:0060535]; vasculature development [GO:0001944]; Wnt signaling pathway [GO:0016055] GO:0001525; GO:0001649; GO:0001701; GO:0001944; GO:0003338; GO:0005109; GO:0005125; GO:0005615; GO:0005737; GO:0005788; GO:0005886; GO:0008283; GO:0008284; GO:0009986; GO:0010628; GO:0016055; GO:0016332; GO:0021846; GO:0021871; GO:0022009; GO:0030182; GO:0030324; GO:0031175; GO:0032364; GO:0032536; GO:0036516; GO:0042475; GO:0042592; GO:0045165; GO:0045669; GO:0045879; GO:0046330; GO:0048018; GO:0048568; GO:0048812; GO:0048864; GO:0050768; GO:0050808; GO:0051145; GO:0060033; GO:0060070; GO:0060425; GO:0060428; GO:0060482; GO:0060484; GO:0060535; GO:0060560; GO:0060669; GO:0060710; GO:0072053; GO:0072054; GO:0072060; GO:0072061; GO:0072205; GO:0072207; GO:0072236; GO:1902262; GO:1902379; GO:1904938 11970 XR_003823974.2 0 0 0 0 53 NA NA NA NA NA NA 11971 XM_029344304.2 0 8 0 0 0 O75762 3.12e-119 Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation-sensitive protein p120) (p120) (Wasabi receptor) Homo sapiens (Human) calcium ion transmembrane transport [GO:0070588]; cell surface receptor signaling pathway [GO:0007166]; cellular calcium ion homeostasis [GO:0006874]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to organic substance [GO:0071310]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; ion transport [GO:0006811]; protein homotetramerization [GO:0051289]; response to cold [GO:0009409]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; sensory perception of pain [GO:0019233]; thermoception [GO:0050955] GO:0005262; GO:0005886; GO:0006811; GO:0006874; GO:0007166; GO:0009409; GO:0009410; GO:0010033; GO:0014070; GO:0015267; GO:0015278; GO:0019233; GO:0032421; GO:0042802; GO:0048265; GO:0050955; GO:0050966; GO:0050968; GO:0051289; GO:0070301; GO:0070588; GO:0071310; GO:0097604 11972 XM_029350227.2 537 441 273 476 182 O43182 8.99e-58 Rho GTPase-activating protein 6 (Rho-type GTPase-activating protein 6) (Rho-type GTPase-activating protein RhoGAPX-1) Homo sapiens (Human) actin filament polymerization [GO:0030041]; activation of phospholipase C activity [GO:0007202]; focal adhesion assembly [GO:0048041]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of stress fiber assembly [GO:0051497]; positive regulation of GTPase activity [GO:0043547]; positive regulation of phospholipase activity [GO:0010518]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266] GO:0005096; GO:0005737; GO:0005829; GO:0005884; GO:0007202; GO:0007266; GO:0010518; GO:0015629; GO:0016004; GO:0017124; GO:0030041; GO:0043274; GO:0043547; GO:0048041; GO:0051056; GO:0051497; GO:0051895 11973 XM_044324677.1 5 4 8 1 18 NA NA NA NA NA NA 11974 XM_029335225.2 702 278 1051 4 790 Q6GM82 0 Alanine aminotransferase 2 (ALT2) (EC 2.6.1.2) (Glutamate pyruvate transaminase 2) (GPT 2) (Glutamic--alanine transaminase 2) (Glutamic--pyruvic transaminase 2) Xenopus laevis (African clawed frog) 2-oxoglutarate metabolic process [GO:0006103]; biosynthetic process [GO:0009058]; L-alanine catabolic process [GO:0042853]; L-alanine metabolic process [GO:0042851] GO:0004021; GO:0006103; GO:0009058; GO:0030170; GO:0042851; GO:0042853 11975 XM_044310680.1 914 650 555 903 993 Q6QI06 0 Rapamycin-insensitive companion of mTOR (AVO3 homolog) (mAVO3) (Protein pianissimo) Mus musculus (Mouse) actin cytoskeleton reorganization [GO:0031532]; cellular response to nutrient levels [GO:0031669]; cytoskeleton organization [GO:0007010]; embryo development ending in birth or egg hatching [GO:0009792]; negative regulation of apoptotic process [GO:0043066]; peptidyl-serine phosphorylation [GO:0018105]; phosphorylation [GO:0016310]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell growth [GO:0030307]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of TOR signaling [GO:0032008]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of establishment of cell polarity [GO:2000114]; regulation of gene expression [GO:0010468]; regulation of GTPase activity [GO:0043087]; regulation of inflammatory response [GO:0050727]; regulation of peptidyl-serine phosphorylation [GO:0033135]; regulation of phosphorylation [GO:0042325]; regulation of protein kinase B signaling [GO:0051896]; regulation of protein phosphorylation [GO:0001932]; TORC2 signaling [GO:0038203] GO:0001932; GO:0001938; GO:0007010; GO:0009792; GO:0010468; GO:0016310; GO:0018105; GO:0019901; GO:0030307; GO:0030838; GO:0031532; GO:0031669; GO:0031932; GO:0032008; GO:0032956; GO:0033135; GO:0038203; GO:0042325; GO:0043022; GO:0043066; GO:0043087; GO:0043539; GO:0050727; GO:0050731; GO:0051896; GO:0051897; GO:0060090; GO:2000114 11976 XM_029323474.1 46 65 157 12 174 NA NA NA NA NA NA 11977 XM_044326048.1 0 18 1 1 0 NA NA NA NA NA NA 11978 XR_003828421.2 59 40 18 56 12 NA NA NA NA NA NA 11979 XM_029333196.2 0 0 0 0 9 Q16281 6.36e-127 Cyclic nucleotide-gated cation channel alpha-3 (Cone photoreceptor cGMP-gated channel subunit alpha) (Cyclic nucleotide-gated channel alpha-3) (CNG channel alpha-3) (CNG-3) (CNG3) Homo sapiens (Human) cation transmembrane transport [GO:0098655]; cation transport [GO:0006812]; inorganic cation import across plasma membrane [GO:0098659]; response to cAMP [GO:0051591]; response to corticosteroid [GO:0031960]; response to magnesium ion [GO:0032026]; signal transduction [GO:0007165]; visual perception [GO:0007601] GO:0005222; GO:0005223; GO:0005737; GO:0005886; GO:0006812; GO:0007165; GO:0007601; GO:0008022; GO:0015276; GO:0017071; GO:0030425; GO:0030553; GO:0031960; GO:0032026; GO:0043194; GO:0043204; GO:0044877; GO:0051591; GO:0097386; GO:0098655; GO:0098659; GO:1902495 11980 XM_044322659.1 0 1 1 9 6 NA NA NA NA NA NA 11981 XM_044321539.1 0 6 0 0 0 NA NA NA NA NA NA 11982 XM_044317174.1 0 274 113 396 334 NA NA NA NA NA NA 11983 XM_029331112.2 990 718 532 718 792 Q8BVF7 7.16e-59 Gamma-secretase subunit APH-1A (APH-1a) (Aph-1alpha) Mus musculus (Mouse) amyloid precursor protein catabolic process [GO:0042987]; amyloid precursor protein metabolic process [GO:0042982]; amyloid-beta formation [GO:0034205]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; metanephros development [GO:0001656]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; positive regulation of catalytic activity [GO:0043085]; positive regulation of endopeptidase activity [GO:0010950]; protein processing [GO:0016485] GO:0001656; GO:0005739; GO:0005769; GO:0005783; GO:0005789; GO:0005794; GO:0005886; GO:0006509; GO:0007219; GO:0007220; GO:0008021; GO:0008233; GO:0010950; GO:0016020; GO:0016485; GO:0019899; GO:0030674; GO:0031293; GO:0032580; GO:0034205; GO:0042734; GO:0042982; GO:0042987; GO:0043085; GO:0061133; GO:0070765; GO:0097060 11984 XM_044317981.1 0 0 0 28 0 NA NA NA NA NA NA 11985 XM_044324733.1 11 0 0 0 5 NA NA NA NA NA NA 11986 XM_029354854.2 179 80 111 317 156 Q80XJ3 3.96e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 11987 XM_029334773.2 140 70 31 47 28 Q2YDF6 9.05e-58 28S ribosomal protein S35, mitochondrial (MRP-S35) (S35mt) (28S ribosomal protein S28, mitochondrial) (MRP-S28) (S28mt) Bos taurus (Bovine) mitochondrial translation [GO:0032543] GO:0003735; GO:0005743; GO:0005763; GO:0032543 11988 XM_044325736.1 333 311 414 251 213 Q9XT06 0 T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha) Monodelphis domestica (Gray short-tailed opossum) protein folding [GO:0006457] GO:0005524; GO:0005815; GO:0005832; GO:0006457; GO:0016887; GO:0051082; GO:0140662 11989 XM_044317543.1 1056 605 731 1488 1812 Q14690 0 Protein RRP5 homolog (NF-kappa-B-binding protein) (NFBP) (Programmed cell death protein 11) Homo sapiens (Human) rRNA processing [GO:0006364] GO:0003723; GO:0005634; GO:0005654; GO:0005730; GO:0005829; GO:0006364; GO:0032040; GO:0051059 11990 XR_003828205.2 66 8 54 45 29 NA NA NA NA NA NA 11991 XM_044319747.1 59 63 45 111 171 NA NA NA NA NA NA 11992 XM_044328918.1 192 167 26 23 89 Q28955 1.26e-65 Protein N-terminal asparagine amidohydrolase (EC 3.5.1.121) (Protein NH2-terminal asparagine amidohydrolase) (PNAA) (Protein NH2-terminal asparagine deamidase) (PNAD) (Protein N-terminal Asn amidase) (Protein NTN-amidase) Sus scrofa (Pig) adult locomotory behavior [GO:0008344]; memory [GO:0007613]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0005634; GO:0005737; GO:0006511; GO:0007613; GO:0008344; GO:0008418 11993 XM_029355557.2 66 15 15 12 75 NA NA NA NA NA NA 11994 XM_044320230.1 25 65 0 98 20 Q91Y77 3.65e-38 Monocarboxylate transporter 10 (MCT 10) (Aromatic amino acid transporter 1) (Solute carrier family 16 member 10) (T-type amino acid transporter 1) Rattus norvegicus (Rat) aromatic amino acid transport [GO:0015801]; thyroid hormone generation [GO:0006590]; thyroid hormone transport [GO:0070327]; thyroid-stimulating hormone secretion [GO:0070460] GO:0005302; GO:0005886; GO:0006590; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0070327; GO:0070460 11995 XM_044317619.1 445 432 34 963 341 Q5I020 1.25e-69 Proton-coupled zinc antiporter SLC30A8 (Solute carrier family 30 member 8) (Zinc transporter 8) (ZnT-8) Xenopus laevis (African clawed frog) zinc ion import into organelle [GO:0062111] GO:0005886; GO:0030658; GO:0030667; GO:0046872; GO:0062111; GO:0140826 11996 XM_044314609.1 37 36 24 79 59 Q7RTR2 6.27e-68 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11997 XM_044314609.1 37 36 24 79 59 Q7RTR2 1.95e-66 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11998 XM_044314609.1 37 36 24 79 59 Q7RTR2 1.21e-63 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11999 XM_044314609.1 37 36 24 79 59 Q7RTR2 1.56e-63 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12000 XM_044314609.1 37 36 24 79 59 Q7RTR2 7.11e-62 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12001 XM_044314609.1 37 36 24 79 59 Q7RTR2 2.31e-43 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12002 XM_044314609.1 37 36 24 79 59 Q7RTR2 3.51e-29 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12003 XM_029328217.2 788 1111 813 733 1399 G8HTB6 8.43e-49 ZP domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 12004 XM_029329017.2 97 37 76 200 98 NA NA NA NA NA NA 12005 XR_006392928.1 41 2 25 5 151 NA NA NA NA NA NA 12006 XR_006394051.1 16 28 16 36 5 NA NA NA NA NA NA 12007 XM_029342332.2 67 0 222 213 78 P50904 0 Ras GTPase-activating protein 1 (GAP) (GTPase-activating protein) (RasGAP) (Ras p21 protein activator) (p120GAP) Rattus norvegicus (Rat) actin cytoskeleton organization [GO:0030036]; activation of GTPase activity [GO:0090630]; blood vessel morphogenesis [GO:0048514]; cell adhesion [GO:0007155]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; male genitalia development [GO:0030539]; mitotic cytokinesis [GO:0000281]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of glucose import [GO:0046326]; positive regulation of GTPase activity [GO:0043547]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; regulation of actin filament polymerization [GO:0030833]; response to insulin [GO:0032868]; response to xenobiotic stimulus [GO:0009410]; signal transduction [GO:0007165]; vasculogenesis [GO:0001570] GO:0000281; GO:0001570; GO:0001726; GO:0001784; GO:0001934; GO:0001953; GO:0005096; GO:0005102; GO:0005161; GO:0005829; GO:0005886; GO:0007155; GO:0007162; GO:0007165; GO:0009410; GO:0016020; GO:0030036; GO:0030539; GO:0030833; GO:0030971; GO:0031965; GO:0032868; GO:0036120; GO:0043066; GO:0043422; GO:0043524; GO:0043547; GO:0044325; GO:0044344; GO:0044877; GO:0046326; GO:0048146; GO:0048514; GO:0050731; GO:0051020; GO:0071364; GO:0090630; GO:1990782 12008 XM_029339346.2 112 163 96 116 143 Q98SN7 2.74e-129 Protein Wnt-2b Gallus gallus (Chicken) camera-type eye photoreceptor cell differentiation [GO:0060219]; canonical Wnt signaling pathway [GO:0060070]; cell population proliferation [GO:0008283]; cornea development in camera-type eye [GO:0061303]; embryonic camera-type eye formation [GO:0060900]; embryonic forelimb morphogenesis [GO:0035115]; iris morphogenesis [GO:0061072]; lens development in camera-type eye [GO:0002088]; limb development [GO:0060173]; morphogenesis of an epithelial sheet [GO:0002011]; negative regulation of glial cell differentiation [GO:0045686]; negative regulation of neuron differentiation [GO:0045665]; neural retina development [GO:0003407]; neuron differentiation [GO:0030182]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of fibroblast growth factor receptor signaling pathway [GO:0045743]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of fibroblast growth factor production [GO:0090270]; retina layer formation [GO:0010842]; Wnt signaling pathway [GO:0016055] GO:0002011; GO:0002088; GO:0003407; GO:0005109; GO:0005576; GO:0008283; GO:0010842; GO:0016055; GO:0030182; GO:0035115; GO:0045665; GO:0045686; GO:0045743; GO:0060070; GO:0060173; GO:0060219; GO:0060828; GO:0060900; GO:0061072; GO:0061303; GO:0090270; GO:0090271 12009 XM_029336411.2 2997 1606 918 1390 810 NA NA NA NA NA NA 12010 XM_044310795.1 0 2 0 0 23 NA NA NA NA NA NA 12011 XR_006392662.1 97 39 79 103 213 NA NA NA NA NA NA 12012 XM_029348960.2 1468 1071 853 1707 1508 P46019 0 Phosphorylase b kinase regulatory subunit alpha, liver isoform (Phosphorylase kinase alpha L subunit) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; generation of precursor metabolites and energy [GO:0006091]; glycogen metabolic process [GO:0005977]; protein modification process [GO:0036211] GO:0004689; GO:0005516; GO:0005829; GO:0005886; GO:0005964; GO:0005975; GO:0005977; GO:0006091; GO:0036211 12013 XM_029344523.2 14 24 0 39 16 P49013 2.3e-29 Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374 12014 XM_029344523.2 14 24 0 39 16 P49013 1.03e-23 Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374 12015 XM_029325296.2 53 0 0 0 0 NA NA NA NA NA NA 12016 XM_044328159.1 32 17 7 0 6 NA NA NA NA NA NA 12017 XR_006395948.1 197 324 168 384 500 NA NA NA NA NA NA 12018 XM_044314537.1 2301 503 462 1509 894 NA NA NA NA NA NA 12019 XM_029355175.2 644 61 196 258 387 Q15256 6e-79 Receptor-type tyrosine-protein phosphatase R (R-PTP-R) (EC 3.1.3.48) (Ch-1PTPase) (NC-PTPCOM1) (Protein-tyrosine phosphatase PCPTP1) Homo sapiens (Human) ERBB2 signaling pathway [GO:0038128]; in utero embryonic development [GO:0001701]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; signal transduction [GO:0007165] GO:0001701; GO:0004725; GO:0005001; GO:0005615; GO:0005829; GO:0005886; GO:0006470; GO:0007165; GO:0010633; GO:0019901; GO:0030054; GO:0035335; GO:0038128; GO:0048471; GO:0070373 12020 XM_029339155.2 775 396 559 518 561 H3ZPL1 1.67e-52 Aromatic-amino-acid aminotransferase 1 (ARAT-I) (AROAT) (EC 2.6.1.57) Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C) biosynthetic process [GO:0009058] GO:0009058; GO:0030170; GO:0080130 12021 XM_044308912.1 393 52 65 0 612 NA NA NA NA NA NA 12022 XM_044320428.1 62 14 0 39 0 NA NA NA NA NA NA 12023 XR_006396342.1 248 633 120 288 485 NA NA NA NA NA NA 12024 XR_006396247.1 69 51 15 57 28 NA NA NA NA NA NA 12025 XM_044321258.1 1249 1236 897 1111 1116 Q9Y673 8.97e-127 Dolichyl-phosphate beta-glucosyltransferase (DolP-glucosyltransferase) (EC 2.4.1.117) (Asparagine-linked glycosylation protein 5 homolog) Homo sapiens (Human) determination of left/right symmetry [GO:0007368]; protein glycosylation [GO:0006486]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279] GO:0004576; GO:0004581; GO:0005789; GO:0006486; GO:0006487; GO:0007368; GO:0016020; GO:0018279 12026 XM_044312992.1 164 0 23 105 0 Q60997 9.52e-34 Deleted in malignant brain tumors 1 protein (Apactin) (CRP-ductin) (Glycoprotein 300) (gp300) (Hensin) (Mucin-like glycoprotein) (Muclin) (Vomeroglandin) (p80) Mus musculus (Mouse) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blastocyst development [GO:0001824]; columnar/cuboidal epithelial cell differentiation [GO:0002065]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterial lipoprotein [GO:0042494]; induction of bacterial agglutination [GO:0043152]; inner cell mass cell proliferation [GO:0001833]; positive regulation of epithelial cell differentiation [GO:0030858]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617] GO:0001530; GO:0001824; GO:0001833; GO:0002065; GO:0003677; GO:0005044; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0009617; GO:0015031; GO:0019898; GO:0030658; GO:0030670; GO:0030858; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0050829; GO:0050830; GO:0050840; GO:0061844; GO:0062023; GO:0070891; GO:1904399 12027 XM_044312992.1 164 0 23 105 0 Q60997 9.57e-30 Deleted in malignant brain tumors 1 protein (Apactin) (CRP-ductin) (Glycoprotein 300) (gp300) (Hensin) (Mucin-like glycoprotein) (Muclin) (Vomeroglandin) (p80) Mus musculus (Mouse) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blastocyst development [GO:0001824]; columnar/cuboidal epithelial cell differentiation [GO:0002065]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterial lipoprotein [GO:0042494]; induction of bacterial agglutination [GO:0043152]; inner cell mass cell proliferation [GO:0001833]; positive regulation of epithelial cell differentiation [GO:0030858]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617] GO:0001530; GO:0001824; GO:0001833; GO:0002065; GO:0003677; GO:0005044; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0009617; GO:0015031; GO:0019898; GO:0030658; GO:0030670; GO:0030858; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0050829; GO:0050830; GO:0050840; GO:0061844; GO:0062023; GO:0070891; GO:1904399 12028 XM_044312992.1 164 0 23 105 0 Q60997 1.99e-28 Deleted in malignant brain tumors 1 protein (Apactin) (CRP-ductin) (Glycoprotein 300) (gp300) (Hensin) (Mucin-like glycoprotein) (Muclin) (Vomeroglandin) (p80) Mus musculus (Mouse) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blastocyst development [GO:0001824]; columnar/cuboidal epithelial cell differentiation [GO:0002065]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterial lipoprotein [GO:0042494]; induction of bacterial agglutination [GO:0043152]; inner cell mass cell proliferation [GO:0001833]; positive regulation of epithelial cell differentiation [GO:0030858]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617] GO:0001530; GO:0001824; GO:0001833; GO:0002065; GO:0003677; GO:0005044; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0009617; GO:0015031; GO:0019898; GO:0030658; GO:0030670; GO:0030858; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0050829; GO:0050830; GO:0050840; GO:0061844; GO:0062023; GO:0070891; GO:1904399 12029 XM_044329241.1 0 39 77 50 39 NA NA NA NA NA NA 12030 XM_029346614.2 497 431 144 72 0 Q5R7H0 0 2-oxoadipate dehydrogenase complex component E1 (E1a) (OADC-E1) (OADH-E1) (EC 1.2.4.-) (2-oxoadipate dehydrogenase, mitochondrial) (Alpha-ketoadipate dehydrogenase) (Alpha-KADH-E1) (Dehydrogenase E1 and transketolase domain-containing protein 1) (Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) generation of precursor metabolites and energy [GO:0006091]; glycolytic process [GO:0006096]; tricarboxylic acid cycle [GO:0006099] GO:0004591; GO:0005739; GO:0005759; GO:0006091; GO:0006096; GO:0006099; GO:0030976 12031 XM_029330279.2 2582 1787 4505 3266 2885 Q9R0N3 1.66e-22 Synaptotagmin-11 (Synaptotagmin XI) (SytXI) Mus musculus (Mouse) autophagy [GO:0006914]; calcium ion regulated lysosome exocytosis [GO:1990927]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; establishment of vesicle localization [GO:0051650]; learning [GO:0007612]; memory [GO:0007613]; negative regulation of clathrin-coated pit assembly [GO:1905469]; negative regulation of clathrin-dependent endocytosis [GO:1900186]; negative regulation of cytokine production [GO:0001818]; negative regulation of dopamine secretion [GO:0033602]; negative regulation of endocytosis [GO:0045806]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of membrane invagination [GO:1905154]; negative regulation of microglial cell activation [GO:1903979]; negative regulation of phagocytosis [GO:0050765]; negative regulation of synaptic vesicle endocytosis [GO:1900243]; negative regulation of tumor necrosis factor production [GO:0032720]; plasma membrane repair [GO:0001778]; positive regulation of protein localization to phagocytic vesicle [GO:1905171]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of defense response to bacterium [GO:1900424]; regulation of dopamine secretion [GO:0014059]; regulation of phagosome maturation [GO:1905162]; regulation of synaptic vesicle endocytosis [GO:1900242]; response to wounding [GO:0009611]; vesicle fusion [GO:0006906]; vesicle-mediated transport [GO:0016192] GO:0000149; GO:0001778; GO:0001786; GO:0001818; GO:0001891; GO:0005509; GO:0005544; GO:0005737; GO:0005764; GO:0005765; GO:0005802; GO:0005886; GO:0006906; GO:0006914; GO:0007612; GO:0007613; GO:0009611; GO:0014059; GO:0014069; GO:0016192; GO:0017156; GO:0017158; GO:0030276; GO:0030424; GO:0030425; GO:0030665; GO:0030672; GO:0031369; GO:0031625; GO:0031982; GO:0032009; GO:0032715; GO:0032720; GO:0033602; GO:0042802; GO:0043005; GO:0043195; GO:0043197; GO:0043204; GO:0044297; GO:0045202; GO:0045335; GO:0045806; GO:0048471; GO:0048487; GO:0048787; GO:0050765; GO:0051650; GO:0055037; GO:0055038; GO:0060076; GO:0060077; GO:0070382; GO:0071277; GO:0098685; GO:0098691; GO:0098793; GO:0098794; GO:1900186; GO:1900242; GO:1900243; GO:1900424; GO:1903979; GO:1905154; GO:1905162; GO:1905171; GO:1905469; GO:1990927 12032 XM_029352425.2 92 90 0 21 215 NA NA NA NA NA NA 12033 XM_044315840.1 407 0 1615 114 10027 NA NA NA NA NA NA 12034 XM_029333026.2 616 677 658 830 924 Q5ZL21 1.18e-73 Cyanocobalamin reductase / alkylcobalamin dealkylase (Alkylcobalamin:glutathione S-alkyltransferase) (EC 2.5.1.151) (CblC) (Cyanocobalamin reductase (cyanide-eliminating)) (EC 1.16.1.6) (Methylmalonic aciduria and homocystinuria type C protein) (MMACHC) Gallus gallus (Chicken) cobalamin metabolic process [GO:0009235]; demethylation [GO:0070988]; glutathione metabolic process [GO:0006749] GO:0005737; GO:0005829; GO:0006749; GO:0009235; GO:0016491; GO:0016740; GO:0031419; GO:0032451; GO:0033787; GO:0043295; GO:0070988; GO:0071949 12035 XM_044319069.1 0 77 43 0 112 Q9VEU6 1.11e-110 Soluble guanylate cyclase 89Da (EC 4.6.1.2) Drosophila melanogaster (Fruit fly) cGMP-mediated signaling [GO:0019934]; nitric oxide-cGMP-mediated signaling pathway [GO:0038060]; response to hypoxia [GO:0001666]; response to oxygen levels [GO:0070482]; response to reactive oxygen species [GO:0000302] GO:0000302; GO:0001666; GO:0004383; GO:0005525; GO:0008074; GO:0019899; GO:0019934; GO:0020037; GO:0038060; GO:0046872; GO:0070482 12036 XM_044327019.1 210 33 112 168 211 NA NA NA NA NA NA 12037 XR_006395473.1 696 456 262 356 141 NA NA NA NA NA NA 12038 XM_029338512.2 11 24 31 28 33 O08658 1.28e-110 Nuclear pore complex protein Nup88 (88 kDa nucleoporin) (Nucleoporin Nup84) (Nucleoporin Nup88) Rattus norvegicus (Rat) mitotic cell cycle [GO:0000278]; mRNA export from nucleus [GO:0006406]; protein import into nucleus [GO:0006606]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056] GO:0000055; GO:0000056; GO:0000278; GO:0005635; GO:0005643; GO:0005654; GO:0006406; GO:0006606; GO:0017056 12039 XR_006392959.1 41 2 25 5 151 NA NA NA NA NA NA 12040 XM_044308193.1 0 277 0 0 0 Q9V9A7 2.65e-166 Probable methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCase subunit beta) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 2) (3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta) Drosophila melanogaster (Fruit fly) coenzyme A metabolic process [GO:0015936]; leucine catabolic process [GO:0006552]; regulation of eclosion [GO:0007563] GO:0004485; GO:0005524; GO:0005739; GO:0005759; GO:0006552; GO:0007563; GO:0015936; GO:1905202 12041 XR_006391358.1 11 14 0 3 21 NA NA NA NA NA NA 12042 XM_044324231.1 76 0 0 98 0 NA NA NA NA NA NA 12043 XM_044320274.1 277 46 415 170 463 Q8N2E2 2.63e-60 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 12044 XR_006392353.1 1 28 0 4 6 NA NA NA NA NA NA 12045 XM_029328600.2 104 0 0 0 64 Q6NYI0 2.23e-25 Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein Danio rerio (Zebrafish) (Brachydanio rerio) endoplasmic reticulum unfolded protein response [GO:0030968] GO:0016020; GO:0030968 12046 XR_006394555.1 2 0 1 2 15 NA NA NA NA NA NA 12047 XM_029329222.2 2724 2100 1240 2098 2403 Q5RDU7 5.2e-62 Protein yippee-like 5 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cell population proliferation [GO:0008283] GO:0000151; GO:0005634; GO:0005737; GO:0005815; GO:0008283; GO:0030496; GO:0046872; GO:0097431 12048 XM_044318028.1 16125 17173 8540 20237 10156 P20825 2.62e-91 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 12049 XM_029326896.2 1011 285 516 731 723 P70704 0 Phospholipid-transporting ATPase IA (EC 7.6.2.1) (ATPase class I type 8A member 1) (Chromaffin granule ATPase II) (P4-ATPase flippase complex alpha subunit ATP8A1) Mus musculus (Mouse) aminophospholipid translocation [GO:0140331]; learning [GO:0007612]; phospholipid translocation [GO:0045332]; positive regulation of cell migration [GO:0030335]; positive regulation of phospholipid translocation [GO:0061092] GO:0000287; GO:0005524; GO:0005783; GO:0005794; GO:0005802; GO:0005886; GO:0007612; GO:0016887; GO:0030335; GO:0030672; GO:0031090; GO:0031410; GO:0042584; GO:0043231; GO:0045202; GO:0045332; GO:0061092; GO:0090556; GO:0140326; GO:0140331; GO:0140346; GO:1990531 12050 XM_029326896.2 1011 285 516 731 723 P70704 1.6e-42 Phospholipid-transporting ATPase IA (EC 7.6.2.1) (ATPase class I type 8A member 1) (Chromaffin granule ATPase II) (P4-ATPase flippase complex alpha subunit ATP8A1) Mus musculus (Mouse) aminophospholipid translocation [GO:0140331]; learning [GO:0007612]; phospholipid translocation [GO:0045332]; positive regulation of cell migration [GO:0030335]; positive regulation of phospholipid translocation [GO:0061092] GO:0000287; GO:0005524; GO:0005783; GO:0005794; GO:0005802; GO:0005886; GO:0007612; GO:0016887; GO:0030335; GO:0030672; GO:0031090; GO:0031410; GO:0042584; GO:0043231; GO:0045202; GO:0045332; GO:0061092; GO:0090556; GO:0140326; GO:0140331; GO:0140346; GO:1990531 12051 XR_006391724.1 15 7 5 0 0 NA NA NA NA NA NA 12052 XM_029335599.2 476 570 304 402 0 O70521 3.96e-37 Regulator of G-protein signaling 19 (RGS19) (G-alpha-interacting protein) (GAIP) Rattus norvegicus (Rat) negative regulation of signal transduction [GO:0009968]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; response to ethanol [GO:0045471] GO:0000139; GO:0001965; GO:0005096; GO:0005737; GO:0005903; GO:0008277; GO:0009968; GO:0016020; GO:0030136; GO:0045121; GO:0045471 12053 XM_044316282.1 12 39 0 0 0 NA NA NA NA NA NA 12054 XR_006394589.1 24 0 0 4 0 NA NA NA NA NA NA 12055 XM_029350752.2 1070 761 489 1083 649 P92208 0 Stress-activated protein kinase JNK (dJNK) (EC 2.7.11.24) (Protein basket) Drosophila melanogaster (Fruit fly) antibacterial humoral response [GO:0019731]; axon extension [GO:0048675]; axon guidance [GO:0007411]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; chorion micropyle formation [GO:0046844]; collateral sprouting of injured axon [GO:0048674]; determination of digestive tract left/right asymmetry [GO:0071907]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal closure, spreading of leading edge cells [GO:0007395]; embryonic anterior midgut (ectodermal) morphogenesis [GO:0048615]; engulfment of apoptotic cell [GO:0043652]; follicle cell of egg chamber development [GO:0030707]; imaginal disc fusion, thorax closure [GO:0046529]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; JUN phosphorylation [GO:0007258]; long-term memory [GO:0007616]; melanization defense response [GO:0035006]; mushroom body development [GO:0016319]; neuron development [GO:0048666]; neuron projection morphogenesis [GO:0048812]; peptidoglycan recognition protein signaling pathway [GO:0061057]; positive regulation of autophagy [GO:0010508]; positive regulation of border follicle cell migration [GO:1903688]; positive regulation of cell death [GO:0010942]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron remodeling [GO:1904801]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; wound healing [GO:0042060]; wound healing, spreading of epidermal cells [GO:0035313] GO:0004672; GO:0004674; GO:0004705; GO:0004707; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006979; GO:0007254; GO:0007258; GO:0007391; GO:0007395; GO:0007411; GO:0007616; GO:0009408; GO:0010508; GO:0010628; GO:0010942; GO:0016319; GO:0019731; GO:0030424; GO:0030425; GO:0030707; GO:0033209; GO:0034599; GO:0034614; GO:0035006; GO:0035313; GO:0035556; GO:0042060; GO:0043652; GO:0046529; GO:0046843; GO:0046844; GO:0048010; GO:0048615; GO:0048666; GO:0048674; GO:0048675; GO:0048803; GO:0048812; GO:0061057; GO:0071243; GO:0071276; GO:0071907; GO:0106310; GO:1903688; GO:1904801 12056 XM_044308099.1 230 174 223 222 259 Q9Z1N2 1.83e-115 Origin recognition complex subunit 1 Mus musculus (Mouse) DNA replication [GO:0006260]; DNA replication initiation [GO:0006270]; mitotic DNA replication checkpoint signaling [GO:0033314]; positive regulation of G0 to G1 transition [GO:0070318]; positive regulation of smooth muscle cell proliferation [GO:0048661] GO:0000781; GO:0000808; GO:0003677; GO:0003682; GO:0003688; GO:0005524; GO:0005634; GO:0005654; GO:0005664; GO:0006260; GO:0006270; GO:0016887; GO:0033314; GO:0046872; GO:0048661; GO:0070318 12057 XM_044322132.1 547 599 374 526 413 NA NA NA NA NA NA 12058 XM_029351882.2 175 159 103 85 79 Q8C9X6 1.46e-119 Enhancer of polycomb homolog 1 Mus musculus (Mouse) double-strand break repair via homologous recombination [GO:0000724]; histone acetylation [GO:0016573]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of striated muscle cell differentiation [GO:0051155]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of chromatin organization [GO:1902275]; regulation of double-strand break repair [GO:2000779]; regulation of transcription by RNA polymerase II [GO:0006357]; sperm DNA condensation [GO:0035092]; spermatid development [GO:0007286] GO:0000122; GO:0000724; GO:0000786; GO:0005634; GO:0005654; GO:0005737; GO:0006357; GO:0007286; GO:0016573; GO:0031965; GO:0032777; GO:0035092; GO:0035267; GO:0042981; GO:0043231; GO:0043967; GO:0043968; GO:0045814; GO:0045892; GO:0045893; GO:0045944; GO:0051155; GO:0051726; GO:0140463; GO:0140767; GO:1902275; GO:1905168; GO:2000779 12059 XM_029357543.2 81 38 32 87 71 Q54IP4 5.93e-23 Dual specificity protein kinase shkB (EC 2.7.11.1) (SH2 domain-containing protein 2) (SH2 domain-containing protein B) Dictyostelium discoideum (Social amoeba) MAPK cascade [GO:0000165] GO:0000165; GO:0004674; GO:0004709; GO:0004713; GO:0005524; GO:0016020; GO:0106310 12060 XM_044321705.1 0 0 0 0 9 NA NA NA NA NA NA 12061 XM_029350402.2 1584 2481 1353 1560 1106 A7RZS0 4.17e-48 Biogenesis of lysosome-related organelles complex 1 subunit 2 (BLOC-1 subunit 2) Nematostella vectensis (Starlet sea anemone) endosomal transport [GO:0016197]; lysosome localization [GO:0032418] GO:0000930; GO:0005765; GO:0016197; GO:0031083; GO:0032418; GO:0043015; GO:0099078 12062 XM_044317671.1 26 0 10 45 7 Q5SPC5 0 Otoferlin (Fer-1-like protein 2) Danio rerio (Zebrafish) (Brachydanio rerio) neuromuscular process controlling balance [GO:0050885]; plasma membrane organization [GO:0007009]; response to auditory stimulus [GO:0010996]; sensory perception of sound [GO:0007605]; startle response [GO:0001964]; synaptic vesicle exocytosis [GO:0016079]; synaptic vesicle priming [GO:0016082] GO:0000139; GO:0001964; GO:0005509; GO:0005789; GO:0007009; GO:0007605; GO:0010996; GO:0016079; GO:0016082; GO:0016323; GO:0030672; GO:0035612; GO:0042995; GO:0048787; GO:0050885 12063 XM_044317671.1 26 0 10 45 7 Q5SPC5 2.22e-106 Otoferlin (Fer-1-like protein 2) Danio rerio (Zebrafish) (Brachydanio rerio) neuromuscular process controlling balance [GO:0050885]; plasma membrane organization [GO:0007009]; response to auditory stimulus [GO:0010996]; sensory perception of sound [GO:0007605]; startle response [GO:0001964]; synaptic vesicle exocytosis [GO:0016079]; synaptic vesicle priming [GO:0016082] GO:0000139; GO:0001964; GO:0005509; GO:0005789; GO:0007009; GO:0007605; GO:0010996; GO:0016079; GO:0016082; GO:0016323; GO:0030672; GO:0035612; GO:0042995; GO:0048787; GO:0050885 12064 XM_044317671.1 26 0 10 45 7 Q5SPC5 2.22e-106 Otoferlin (Fer-1-like protein 2) Danio rerio (Zebrafish) (Brachydanio rerio) neuromuscular process controlling balance [GO:0050885]; plasma membrane organization [GO:0007009]; response to auditory stimulus [GO:0010996]; sensory perception of sound [GO:0007605]; startle response [GO:0001964]; synaptic vesicle exocytosis [GO:0016079]; synaptic vesicle priming [GO:0016082] GO:0000139; GO:0001964; GO:0005509; GO:0005789; GO:0007009; GO:0007605; GO:0010996; GO:0016079; GO:0016082; GO:0016323; GO:0030672; GO:0035612; GO:0042995; GO:0048787; GO:0050885 12065 XR_006392752.1 2 11 14 0 0 NA NA NA NA NA NA 12066 XM_044325759.1 59 337 34 293 194 Q6CGG3 1.08e-33 FK506-binding protein 2 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica) chaperone-mediated protein folding [GO:0061077]; protein peptidyl-prolyl isomerization [GO:0000413] GO:0000413; GO:0003755; GO:0005783; GO:0061077 12067 XM_044309567.1 7 0 0 0 17 NA NA NA NA NA NA 12068 XM_044307546.1 52 14 24 18 67 O00463 1.11e-32 TNF receptor-associated factor 5 (RING finger protein 84) Homo sapiens (Human) apoptotic process [GO:0006915]; interleukin-17-mediated signaling pathway [GO:0097400]; mRNA stabilization [GO:0048255]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of JNK cascade [GO:0046330]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; signal transduction [GO:0007165]; signal transduction involved in regulation of gene expression [GO:0023019]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0005164; GO:0005813; GO:0005829; GO:0006915; GO:0007165; GO:0008270; GO:0008284; GO:0009898; GO:0023019; GO:0031625; GO:0031996; GO:0033209; GO:0035631; GO:0042802; GO:0042981; GO:0043122; GO:0043123; GO:0046330; GO:0048255; GO:0051091; GO:0051092; GO:0070534; GO:0097400 12069 XM_044325436.1 112 18 24 32 59 Q6QNK2 2.04e-63 Adhesion G-protein coupled receptor D1 (G-protein coupled receptor 133) (G-protein coupled receptor PGR25) Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0005654; GO:0005886; GO:0007166; GO:0007186; GO:0007189; GO:0016020 12070 XM_044323990.1 10 381 9 711 146 NA NA NA NA NA NA 12071 XM_044313862.1 3819 5338 2359 5495 6263 Q10567 0 AP-1 complex subunit beta-1 (Adaptor protein complex AP-1 subunit beta-1) (Adaptor-related protein complex 1 subunit beta-1) (Beta-1-adaptin) (Beta-adaptin 1) (Clathrin assembly protein complex 1 beta large chain) (Golgi adaptor HA1/AP1 adaptin beta subunit) Homo sapiens (Human) basolateral protein secretion [GO:0110010]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; intracellular protein transport [GO:0006886]; kidney development [GO:0001822]; melanosome assembly [GO:1903232]; platelet dense granule organization [GO:0060155]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0001822; GO:0005765; GO:0005769; GO:0005794; GO:0005829; GO:0006886; GO:0007368; GO:0007507; GO:0016192; GO:0019901; GO:0030121; GO:0030276; GO:0030659; GO:0032588; GO:0043231; GO:0060155; GO:0110010; GO:1903232 12072 XR_006391750.1 45 15 43 35 143 NA NA NA NA NA NA 12073 XM_029350679.2 255 16 56 10 61 Q9I8C7 7.12e-80 Neuronal acetylcholine receptor subunit alpha-10 (Alpha 10 nAChR) (Nicotinic acetylcholine receptor subunit alpha-10) (NACHR alpha-10) Gallus gallus (Chicken) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; response to auditory stimulus [GO:0010996]; signal transduction [GO:0007165] GO:0004888; GO:0005231; GO:0005262; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0010996; GO:0022848; GO:0030594; GO:0034220; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051899; GO:1904315 12074 XM_044316706.1 0 0 0 30 144 NA NA NA NA NA NA 12075 XM_029358096.2 1452 774 579 974 884 Q8CAL5 1.38e-33 Glypican-5 [Cleaved into: Secreted glypican-5] Mus musculus (Mouse) cell migration [GO:0016477]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; regulation of protein localization to membrane [GO:1905475] GO:0005615; GO:0005796; GO:0005886; GO:0009986; GO:0016477; GO:0062023; GO:0090263; GO:1905475 12076 XM_029338497.2 165 24 0 66 11 Q16932 3.41e-101 Syntaxin Aplysia californica (California sea hare) intracellular protein transport [GO:0006886]; neurotransmitter transport [GO:0006836]; vesicle-mediated transport [GO:0016192] GO:0005484; GO:0006836; GO:0006886; GO:0016020; GO:0016192 12077 XR_003823998.2 75 49 28 78 48 NA NA NA NA NA NA 12078 XM_044328635.1 34 0 34 0 189 NA NA NA NA NA NA 12079 XM_044323046.1 439 544 255 403 387 NA NA NA NA NA NA 12080 XM_029357009.2 258 195 123 163 239 Q8R2L5 2.53e-22 28S ribosomal protein S18c, mitochondrial (MRP-S18-c) (Mrps18-c) (S18mt-c) (28S ribosomal protein S18-1, mitochondrial) (MRP-S18-1) Mus musculus (Mouse) mitochondrial translation [GO:0032543] GO:0003735; GO:0005739; GO:0005743; GO:0005763; GO:0032543; GO:0070181 12081 XM_029336632.2 21 14 32 95 21 P08419 6.28e-57 Chymotrypsin-like elastase family member 2A (EC 3.4.21.71) (Elastase-2) (Elastase-2A) Sus scrofa (Pig) insulin catabolic process [GO:1901143]; proteolysis [GO:0006508]; regulation of insulin secretion [GO:0050796]; regulation of platelet aggregation [GO:0090330]; response to insulin [GO:0032868] GO:0004175; GO:0004252; GO:0005576; GO:0005615; GO:0006508; GO:0032868; GO:0050796; GO:0090330; GO:1901143 12082 XM_044308636.1 954 932 816 908 1748 Q66JF3 7.33e-152 MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (MAPK signal-integrating kinase 1) (Mnk1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) protein phosphorylation [GO:0006468]; regulation of translation [GO:0006417] GO:0004674; GO:0005524; GO:0006417; GO:0006468; GO:0046872; GO:0106310 12083 XR_006395158.1 33 4 6 44 13 NA NA NA NA NA NA 12084 XM_044328128.1 9 0 68 47 34 NA NA NA NA NA NA 12085 XM_029348913.2 105 100 290 233 425 O16025 0 Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (AOS) (EC 4.2.1.-) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)] Plexaura homomalla (Black sea rod) arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; lipid oxidation [GO:0034440]; oxylipin biosynthetic process [GO:0031408] GO:0005506; GO:0005737; GO:0006633; GO:0009978; GO:0016020; GO:0019369; GO:0020037; GO:0031408; GO:0034440; GO:0047677 12086 XM_029333349.2 3642 835 1374 3498 3232 Q26614 4.23e-140 Fibroblast growth factor receptor (SpFGFR) (EC 2.7.10.1) Strongylocentrotus purpuratus (Purple sea urchin) positive regulation of kinase activity [GO:0033674]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0004714; GO:0005007; GO:0005524; GO:0005886; GO:0007169; GO:0017134; GO:0033674; GO:0043235 12087 XR_006395466.1 10 1 48 6 133 NA NA NA NA NA NA 12088 XM_029330455.2 386 101 0 128 103 NA NA NA NA NA NA 12089 XM_029348160.2 1755 638 465 884 643 P56962 3.26e-42 Syntaxin-17 Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagosome membrane docking [GO:0016240]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum-Golgi intermediate compartment organization [GO:0097111]; exocytosis [GO:0006887]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886]; protein localization to phagophore assembly site [GO:0034497]; vesicle docking [GO:0048278]; vesicle fusion [GO:0006906] GO:0000149; GO:0000421; GO:0005484; GO:0005739; GO:0005776; GO:0005789; GO:0005793; GO:0005829; GO:0005886; GO:0006886; GO:0006887; GO:0006888; GO:0006906; GO:0007030; GO:0012505; GO:0012507; GO:0016020; GO:0016240; GO:0019901; GO:0019903; GO:0030134; GO:0030868; GO:0031201; GO:0033116; GO:0034497; GO:0044233; GO:0048278; GO:0097111; GO:0097352 12090 XM_029354058.2 40 0 15 25 76 P30834 1.67e-44 Cytolysin tenebrosin-B (DELTA-actitoxin) Actinia tenebrosa (Australian red waratah sea anemone) cation transport [GO:0006812]; cytolysis in another organism [GO:0051715]; pore complex assembly [GO:0046931] GO:0005576; GO:0006812; GO:0015267; GO:0042151; GO:0044218; GO:0046930; GO:0046931; GO:0051715; GO:0090729 12091 XM_044306949.1 25 0 48 1 50 NA NA NA NA NA NA 12092 XM_044325837.1 0 0 13 0 205 P51029 2.06e-71 Protein Wnt-8b Danio rerio (Zebrafish) (Brachydanio rerio) canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; commissural neuron axon guidance [GO:0071679]; embryonic pattern specification [GO:0009880]; eye development [GO:0001654]; eye field cell fate commitment involved in camera-type eye formation [GO:0060898]; forebrain development [GO:0030900]; forebrain neuron differentiation [GO:0021879]; hypothalamus development [GO:0021854]; negative regulation of anterior neural cell fate commitment of the neural plate by Wnt signaling pathway [GO:0022002]; neuron differentiation [GO:0030182]; otic placode formation [GO:0043049]; sensory epithelium regeneration [GO:0070654] GO:0001654; GO:0005109; GO:0005125; GO:0005615; GO:0009880; GO:0021854; GO:0021879; GO:0022002; GO:0030182; GO:0030900; GO:0043049; GO:0045165; GO:0060070; GO:0060898; GO:0070654; GO:0071679 12093 XM_029343543.2 803 658 363 644 541 A6H7B5 2.84e-167 COP9 signalosome complex subunit 3 (SGN3) (Signalosome subunit 3) Bos taurus (Bovine) in utero embryonic development [GO:0001701]; protein deneddylation [GO:0000338]; regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:1902162] GO:0000338; GO:0001701; GO:0005654; GO:0005829; GO:0008180; GO:0048471; GO:1902162 12094 XM_029341073.2 330 124 168 295 373 Q969H0 1.16e-58 F-box/WD repeat-containing protein 7 (Archipelago homolog) (hAgo) (F-box and WD-40 domain-containing protein 7) (F-box protein FBX30) (SEL-10) (hCdc4) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; DNA repair [GO:0006281]; lipid homeostasis [GO:0055088]; lung development [GO:0030324]; negative regulation of gene expression [GO:0010629]; negative regulation of hepatocyte proliferation [GO:2000346]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of osteoclast development [GO:2001205]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; negative regulation of SREBP signaling pathway [GO:2000639]; negative regulation of triglyceride biosynthetic process [GO:0010868]; Notch signaling pathway [GO:0007219]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903378]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein destabilization [GO:0031648]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of cell cycle G1/S phase transition [GO:1902806]; regulation of cell migration involved in sprouting angiogenesis [GO:0090049]; regulation of circadian rhythm [GO:0042752]; regulation of lipid storage [GO:0010883]; regulation of protein localization [GO:0032880]; rhythmic process [GO:0048511]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; sister chromatid cohesion [GO:0007062]; ubiquitin recycling [GO:0010992]; vasculature development [GO:0001944]; vasculogenesis [GO:0001570] GO:0001570; GO:0001944; GO:0005634; GO:0005654; GO:0005694; GO:0005730; GO:0005737; GO:0005739; GO:0005783; GO:0005794; GO:0005829; GO:0006281; GO:0006974; GO:0007062; GO:0007219; GO:0010629; GO:0010868; GO:0010883; GO:0010992; GO:0016567; GO:0019005; GO:0030324; GO:0030332; GO:0030674; GO:0031146; GO:0031398; GO:0031625; GO:0031648; GO:0032880; GO:0032991; GO:0034644; GO:0042752; GO:0042802; GO:0043130; GO:0043161; GO:0045741; GO:0045746; GO:0048471; GO:0048511; GO:0050816; GO:0050821; GO:0051443; GO:0055088; GO:0070374; GO:0090049; GO:0097027; GO:1901800; GO:1902806; GO:1903026; GO:1903146; GO:1903378; GO:1903955; GO:1990452; GO:2000060; GO:2000346; GO:2000639; GO:2001205 12095 XM_044327725.1 819 198 307 787 515 O08760 6.74e-103 N-glycosylase/DNA lyase [Includes: 8-oxoguanine DNA glycosylase (EC 3.2.2.-); DNA-(apurinic or apyrimidinic site) lyase (AP lyase) (EC 4.2.99.18)] Mus musculus (Mouse) acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of DNA-templated transcription [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]; response to xenobiotic stimulus [GO:0009410] GO:0000702; GO:0002526; GO:0003677; GO:0003684; GO:0005634; GO:0005654; GO:0005739; GO:0006281; GO:0006284; GO:0006285; GO:0006355; GO:0006974; GO:0006979; GO:0007568; GO:0008017; GO:0008534; GO:0009314; GO:0009410; GO:0009416; GO:0016363; GO:0016607; GO:0019104; GO:0032355; GO:0032357; GO:0032991; GO:0033683; GO:0034039; GO:0043066; GO:0045471; GO:0051593; GO:0071276; GO:0140078; GO:1901291 12096 XM_029349134.2 790 1095 496 653 501 Q7ZT46 6.37e-67 DNA replication complex GINS protein PSF2 (GINS complex subunit 2) Xenopus laevis (African clawed frog) DNA replication [GO:0006260]; DNA strand elongation involved in DNA replication [GO:0006271]; regulation of DNA-templated transcription elongation [GO:0032784] GO:0000811; GO:0003682; GO:0005634; GO:0005654; GO:0006260; GO:0006271; GO:0032784; GO:0071162 12097 XM_029355846.2 318 157 46 72 533 O00339 1.78e-72 Matrilin-2 Homo sapiens (Human) extracellular matrix organization [GO:0030198] GO:0005201; GO:0005509; GO:0005576; GO:0030198; GO:0031012; GO:0062023; GO:0120216 12098 XM_029355846.2 318 157 46 72 533 O00339 1.89e-36 Matrilin-2 Homo sapiens (Human) extracellular matrix organization [GO:0030198] GO:0005201; GO:0005509; GO:0005576; GO:0030198; GO:0031012; GO:0062023; GO:0120216 12099 XR_006391593.1 5664 6593 2746 4205 8517 NA NA NA NA NA NA 12100 XM_044322104.1 1728 1262 712 923 567 Q9UA35 2.17e-148 Solute carrier family 28 member 3 (Concentrative Na(+)-nucleoside cotransporter 3) (hfCNT) Eptatretus stoutii (Pacific hagfish) NA GO:0005337; GO:0005886; GO:0015293 12101 XM_029355925.2 79 107 48 57 193 Q8BWQ4 7.5e-98 Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 (EC 2.1.1.296) (Cap methyltransferase 2) (Cap2 2'O-ribose methyltransferase 2) (MTr2) (FtsJ methyltransferase domain-containing protein 1) Mus musculus (Mouse) 7-methylguanosine mRNA capping [GO:0006370]; cap1 mRNA methylation [GO:0097309]; cap2 mRNA methylation [GO:0097310] GO:0004483; GO:0005634; GO:0005737; GO:0006370; GO:0097309; GO:0097310 12102 XM_029330446.2 131 168 526 466 421 NA NA NA NA NA NA 12103 XM_044307707.1 6 1 11 31 144 NA NA NA NA NA NA 12104 XM_044316425.1 11 1 0 13 2 NA NA NA NA NA NA 12105 XR_006397699.1 0 29 170 0 57 NA NA NA NA NA NA 12106 XM_044326251.1 2 17 30 0 45 NA NA NA NA NA NA 12107 XM_029333318.2 0 0 48 0 164 Q12923 2.1e-57 Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1) (PTP-BAS) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (Protein-tyrosine phosphatase PTPL1) Homo sapiens (Human) cellular response to toxic substance [GO:0097237]; negative regulation of excitatory synapse assembly [GO:1904890]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066] GO:0001650; GO:0001933; GO:0004725; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0006470; GO:0014066; GO:0030027; GO:0035335; GO:0036312; GO:0043005; GO:0044297; GO:0070062; GO:0097237; GO:1904890 12108 XM_029333318.2 0 0 48 0 164 Q12923 1.77e-28 Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1) (PTP-BAS) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (Protein-tyrosine phosphatase PTPL1) Homo sapiens (Human) cellular response to toxic substance [GO:0097237]; negative regulation of excitatory synapse assembly [GO:1904890]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066] GO:0001650; GO:0001933; GO:0004725; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0006470; GO:0014066; GO:0030027; GO:0035335; GO:0036312; GO:0043005; GO:0044297; GO:0070062; GO:0097237; GO:1904890 12109 XM_029326318.2 1 39 66 23 31 NA NA NA NA NA NA 12110 XM_044324054.1 0 2 0 0 17 Q810D6 1.7e-32 Glutamate-rich WD repeat-containing protein 1 (Protein A301) Mus musculus (Mouse) DNA replication [GO:0006260]; nucleosome assembly [GO:0006334]; nucleosome disassembly [GO:0006337]; ribosome biogenesis [GO:0042254] GO:0003682; GO:0003688; GO:0005634; GO:0005654; GO:0005694; GO:0005730; GO:0005829; GO:0006260; GO:0006334; GO:0006337; GO:0032991; GO:0042254; GO:0042393 12111 XM_044324054.1 0 2 0 0 17 Q810D6 1.7e-32 Glutamate-rich WD repeat-containing protein 1 (Protein A301) Mus musculus (Mouse) DNA replication [GO:0006260]; nucleosome assembly [GO:0006334]; nucleosome disassembly [GO:0006337]; ribosome biogenesis [GO:0042254] GO:0003682; GO:0003688; GO:0005634; GO:0005654; GO:0005694; GO:0005730; GO:0005829; GO:0006260; GO:0006334; GO:0006337; GO:0032991; GO:0042254; GO:0042393 12112 XM_044327164.1 327 414 304 355 835 P46461 0 Vesicle-fusing ATPase 1 (EC 3.6.4.6) (N-ethylmaleimide-sensitive fusion protein 1) (NEM-sensitive fusion protein 1) (Protein comatose) (Vesicular-fusion protein NSF1) (dNsf-1) (NSF-1) Drosophila melanogaster (Fruit fly) autophagy [GO:0006914]; Golgi organization [GO:0007030]; Golgi to lysosome transport [GO:0090160]; Golgi to plasma membrane protein transport [GO:0043001]; intra-Golgi vesicle-mediated transport [GO:0006891]; neuromuscular synaptic transmission [GO:0007274]; neuron cellular homeostasis [GO:0070050]; neurotransmitter secretion [GO:0007269]; regulation of neuromuscular synaptic transmission [GO:1900073]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; SNARE complex disassembly [GO:0035494]; synaptic vesicle cycle [GO:0099504]; synaptic vesicle fusion to presynaptic active zone membrane [GO:0031629]; synaptic vesicle priming [GO:0016082] GO:0005524; GO:0005737; GO:0005795; GO:0006891; GO:0006914; GO:0007030; GO:0007269; GO:0007274; GO:0016082; GO:0016887; GO:0031594; GO:0031629; GO:0035494; GO:0043001; GO:0043195; GO:0046872; GO:0048172; GO:0070050; GO:0090160; GO:0098527; GO:0099504; GO:0099523; GO:1900073 12113 XM_029326716.2 84 37 63 108 157 D3YXG0 0 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 12114 XM_029326716.2 84 37 63 108 157 D3YXG0 2.77e-153 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 12115 XM_029326716.2 84 37 63 108 157 D3YXG0 1.4e-139 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 12116 XM_029326716.2 84 37 63 108 157 D3YXG0 5.52e-109 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 12117 XM_029326716.2 84 37 63 108 157 D3YXG0 1.45e-103 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 12118 XM_029326716.2 84 37 63 108 157 D3YXG0 5.58e-96 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 12119 XM_029326716.2 84 37 63 108 157 D3YXG0 3.45e-95 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 12120 XM_029326716.2 84 37 63 108 157 D3YXG0 3.75e-88 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 12121 XM_029326716.2 84 37 63 108 157 D3YXG0 1.73e-84 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 12122 XM_029326716.2 84 37 63 108 157 D3YXG0 8e-81 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 12123 XM_029326716.2 84 37 63 108 157 D3YXG0 5.34e-27 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 12124 XM_029326716.2 84 37 63 108 157 D3YXG0 2.19e-25 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 12125 XM_029326716.2 84 37 63 108 157 D3YXG0 5.33e-25 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 12126 XM_044326520.1 17 0 10 52 72 NA NA NA NA NA NA 12127 XM_029343091.2 78 86 55 143 42 NA NA NA NA NA NA 12128 XM_029342415.2 51 89 226 165 240 P16157 6.59e-94 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 12129 XM_029342415.2 51 89 226 165 240 P16157 3.24e-86 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 12130 XM_029342415.2 51 89 226 165 240 P16157 9.39e-86 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 12131 XM_044311961.1 4 7 1 12 2 NA NA NA NA NA NA 12132 XR_003828645.2 1 0 5 0 14 NA NA NA NA NA NA 12133 XM_029333765.2 1609 1362 846 1178 1065 Q6P819 0 CCR4-NOT transcription complex subunit 9 (Cell differentiation protein RQCD1 homolog) (Rcd-1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) mRNA catabolic process [GO:0006402]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; regulation of translation [GO:0006417]; RNA-mediated gene silencing [GO:0031047] GO:0000932; GO:0005634; GO:0006402; GO:0006417; GO:0030014; GO:0030374; GO:0031047; GO:0033147 12134 XM_029342760.2 144 17 70 96 90 Q9V9S7 7.91e-48 Rho GTPase-activating protein 100F (RhoGAP-100F) (Synapse defective protein 1 homolog) (Protein syd-1 homolog) Drosophila melanogaster (Fruit fly) activation of GTPase activity [GO:0090630]; axon extension involved in axon guidance [GO:0048846]; cell migration [GO:0016477]; cell projection organization [GO:0030030]; cytoskeletal matrix organization at active zone [GO:0048789]; maintenance of presynaptic active zone structure [GO:0048790]; presynaptic active zone organization [GO:1990709]; R7 cell development [GO:0045467]; regulation of Ras protein signal transduction [GO:0046578]; Rho protein signal transduction [GO:0007266]; synapse assembly [GO:0007416]; synaptic vesicle localization [GO:0097479] GO:0005096; GO:0007266; GO:0007416; GO:0016477; GO:0030030; GO:0031594; GO:0045467; GO:0046578; GO:0048786; GO:0048789; GO:0048790; GO:0048846; GO:0090630; GO:0097060; GO:0097479; GO:0098831; GO:1990709 12135 XM_029351396.2 0 0 0 64 42 A0A1L8F5J9 2.75e-51 Glutamate receptor ionotropic, NMDA 1 (GluN1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1) Xenopus laevis (African clawed frog) response to zinc ion [GO:0010043] GO:0004972; GO:0005886; GO:0010043; GO:0017146; GO:0045211; GO:0046872 12136 XM_044322798.1 507 809 522 203 297 NA NA NA NA NA NA 12137 XM_029330002.2 0 0 35 83 9 Q9TTT5 8.07e-91 Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3) Oryctolagus cuniculus (Rabbit) protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0008076; GO:0030425; GO:0034765; GO:0042383; GO:0046872; GO:0051260 12138 XM_029337599.2 0 1 33 16 20 NA NA NA NA NA NA 12139 XM_029343000.2 518 344 231 257 366 NA NA NA NA NA NA 12140 XM_044327611.1 600 448 172 496 503 Q9P203 3.64e-116 BTB/POZ domain-containing protein 7 Homo sapiens (Human) morphogenesis of a branching epithelium [GO:0061138]; regulation of branching involved in salivary gland morphogenesis [GO:0060693] GO:0005634; GO:0060693; GO:0061138 12141 XR_003824256.2 0 0 8 9 6 NA NA NA NA NA NA 12142 XM_029340995.2 49 4 37 83 84 NA NA NA NA NA NA 12143 XM_044319117.1 14 0 13 23 29 NA NA NA NA NA NA 12144 XM_029331336.2 144 117 106 185 186 Q642C0 9.05e-55 DnaJ homolog subfamily C member 8 Rattus norvegicus (Rat) NA GO:0005634; GO:0030544 12145 XM_029335902.2 948 993 450 835 542 Q9CYI0 4.45e-42 Protein Njmu-R1 Mus musculus (Mouse) intracellular protein transport [GO:0006886]; vesicle tethering to Golgi [GO:0099041] GO:0005802; GO:0006886; GO:0031410; GO:0099041 12146 XM_029344507.2 29 35 40 19 35 NA NA NA NA NA NA 12147 XM_044312491.1 306 319 249 285 211 Q5ZKE7 3.74e-49 UMP-CMP kinase (EC 2.7.4.14) (Deoxycytidylate kinase) (CK) (dCMP kinase) (Nucleoside-diphosphate kinase) (EC 2.7.4.6) (Uridine monophosphate/cytidine monophosphate kinase) (UMP/CMP kinase) (UMP/CMPK) Gallus gallus (Chicken) 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; CDP biosynthetic process [GO:0046705]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; UDP biosynthetic process [GO:0006225] GO:0004127; GO:0004550; GO:0005524; GO:0005634; GO:0005737; GO:0006165; GO:0006207; GO:0006225; GO:0009142; GO:0033862; GO:0036430; GO:0036431; GO:0046705 12148 XM_044327584.1 121 0 106 161 85 A7YSY2 0 Ribosome biogenesis protein SPATA5L1 (EC 3.6.4.10) (Spermatogenesis-associated protein 5-like protein 1) Bos taurus (Bovine) ribosomal large subunit biogenesis [GO:0042273] GO:0005524; GO:0005634; GO:0005737; GO:0005819; GO:0016887; GO:0042273; GO:1990275 12149 XM_044326746.1 0 8 0 88 44 Q9UTA8 2.61e-24 Uncharacterized methyltransferase-like C25B8.10 (EC 2.1.1.-) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) cellular detoxification [GO:1990748]; methylation [GO:0032259] GO:0005634; GO:0005829; GO:0008168; GO:0032259; GO:0046547; GO:1990748 12150 XM_044323216.1 0 0 12 3 65 NA NA NA NA NA NA 12151 XM_029343884.2 2552 2283 1391 1624 1814 Q6R1L1 3.14e-52 Transcription initiation factor TFIID subunit 7 Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) spermine transport [GO:0000296]; transcription initiation at RNA polymerase II promoter [GO:0006367] GO:0000296; GO:0005669; GO:0006367; GO:0071339 12152 XM_029353499.2 26819 9945 17989 18033 14267 P28648 5.21e-26 CD63 antigen (Mast cell antigen AD1) (CD antigen CD63) Rattus norvegicus (Rat) cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; endosome to melanosome transport [GO:0035646]; epithelial cell differentiation [GO:0030855]; negative regulation of epithelial cell migration [GO:0010633]; pigment cell differentiation [GO:0050931]; pigment granule maturation [GO:0048757]; pigmentation [GO:0043473]; positive regulation of cell adhesion [GO:0045785]; positive regulation of endocytosis [GO:0045807]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of receptor internalization [GO:0002092]; protein localization [GO:0008104]; protein transport [GO:0015031]; regulation of potassium ion transmembrane transport [GO:1901379]; regulation of vascular endothelial growth factor signaling pathway [GO:1900746] GO:0002092; GO:0005615; GO:0005737; GO:0005764; GO:0005765; GO:0005770; GO:0005886; GO:0007160; GO:0008104; GO:0009986; GO:0010008; GO:0010633; GO:0015031; GO:0016020; GO:0016477; GO:0030855; GO:0031902; GO:0031904; GO:0032585; GO:0032991; GO:0035646; GO:0042470; GO:0043473; GO:0044877; GO:0045785; GO:0045807; GO:0048757; GO:0050931; GO:0070062; GO:0097487; GO:1900746; GO:1901379; GO:2001046 12153 XM_029327523.2 0 0 2 11 0 NA NA NA NA NA NA 12154 XM_029355871.2 344 149 188 195 223 Q8BJ37 9.58e-151 Tyrosyl-DNA phosphodiesterase 1 (Tyr-DNA phosphodiesterase 1) (EC 3.1.4.-) (Protein expressed in male leptotene and zygotene spermatocytes 501) (MLZ-501) Mus musculus (Mouse) DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; single strand break repair [GO:0000012] GO:0000012; GO:0003690; GO:0003697; GO:0004527; GO:0005634; GO:0005654; GO:0005886; GO:0006281; GO:0006302; GO:0017005; GO:0043231 12155 XM_044321091.1 42 0 17 24 212 Q805E5 7.11e-78 Carbohydrate sulfotransferase 14 (EC 2.8.2.-) (Dermatan 4-sulfotransferase 1) (D4ST-1) (zD4ST-1) Danio rerio (Zebrafish) (Brachydanio rerio) carbohydrate biosynthetic process [GO:0016051]; dermatan sulfate proteoglycan metabolic process [GO:0050655] GO:0000139; GO:0001537; GO:0008146; GO:0016051; GO:0050655 12156 XR_006391940.1 169 67 78 121 213 NA NA NA NA NA NA 12157 XM_044323083.1 371 233 146 219 444 P0C7P0 2.31e-25 CDGSH iron-sulfur domain-containing protein 3, mitochondrial (MitoNEET-related protein 2) (Miner2) (Mitochondrial inner NEET protein) (MiNT) Homo sapiens (Human) protein maturation by [2Fe-2S] cluster transfer [GO:0106034] GO:0005739; GO:0046872; GO:0051537; GO:0106034 12158 XM_029353850.2 5345 5008 2511 3260 3011 Q7PVX8 8.31e-134 Probable actin-related protein 2/3 complex subunit 2 (Arp2/3 complex 34 kDa subunit) (p34-ARC) Anopheles gambiae (African malaria mosquito) actin filament polymerization [GO:0030041]; Arp2/3 complex-mediated actin nucleation [GO:0034314] GO:0005200; GO:0005737; GO:0005885; GO:0030041; GO:0034314; GO:0051015 12159 XM_029333404.2 148 127 250 183 994 NA NA NA NA NA NA 12160 XM_029343522.2 26 46 23 24 52 Q99315 1.12e-81 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 12161 XM_044316028.1 434 123 224 164 1073 Q54H55 3.14e-30 FAD-linked oxidoreductase DDB_G0289697 (EC 1.-.-.-) Dictyostelium discoideum (Social amoeba) NA GO:0016491; GO:0071949 12162 XM_044323401.1 0 11 116 202 19 NA NA NA NA NA NA 12163 XR_006392532.1 28 12 13 12 10 NA NA NA NA NA NA 12164 XM_029357594.2 162 123 99 35 66 NA NA NA NA NA NA 12165 XM_044309478.1 36 34 28 12 149 NA NA NA NA NA NA 12166 XM_029353602.2 49 3 20 10 52 NA NA NA NA NA NA 12167 XR_006393582.1 37 10 0 38 0 NA NA NA NA NA NA 12168 XR_006391359.1 15 7 0 27 31 NA NA NA NA NA NA 12169 XM_029350026.2 329 82 89 137 188 Q2ABP2 8.67e-49 Post-GPI attachment to proteins factor 2 (FGF receptor-activating protein 1) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) GPI anchor biosynthetic process [GO:0006506] GO:0000139; GO:0005789; GO:0006506 12170 XM_029331974.2 3061 2966 2417 2619 2741 Q15742 1.08e-21 NGFI-A-binding protein 2 (EGR-1-binding protein 2) (Melanoma-associated delayed early response protein) (Protein MADER) Homo sapiens (Human) endochondral ossification [GO:0001958]; myelination [GO:0042552]; negative regulation of transcription by RNA polymerase III [GO:0016480]; positive regulation of tau-protein kinase activity [GO:1902949]; regulation of DNA-templated transcription [GO:0006355]; regulation of epidermis development [GO:0045682]; Schwann cell differentiation [GO:0014037] GO:0001958; GO:0003712; GO:0003714; GO:0005634; GO:0005654; GO:0006355; GO:0014037; GO:0016480; GO:0042552; GO:0042802; GO:0045682; GO:1902949 12171 XM_029330931.2 235 59 56 105 157 NA NA NA NA NA NA 12172 XM_044313298.1 63 57 12 65 50 NA NA NA NA NA NA 12173 XR_003826161.2 17 0 14 4 12 NA NA NA NA NA NA 12174 XM_029346152.2 164 111 61 100 28 Q9EPI9 0 Potassium voltage-gated channel subfamily H member 5 (Ether-a-go-go potassium channel 2) (rEAG2) (Voltage-gated potassium channel subunit Kv10.2) Rattus norvegicus (Rat) potassium ion transmembrane transport [GO:0071805]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391] GO:0005249; GO:0005516; GO:0005886; GO:0009986; GO:0010389; GO:0034765; GO:0042391; GO:0044325; GO:0044877; GO:0071805 12175 XR_006392706.1 1150 247 102 2323 160 NA NA NA NA NA NA 12176 XM_029344902.2 4392 2797 2238 3070 3241 Q86WC4 1.41e-24 Osteopetrosis-associated transmembrane protein 1 (Chloride channel 7 beta subunit) Homo sapiens (Human) osteoclast differentiation [GO:0030316]; transepithelial chloride transport [GO:0030321] GO:0005765; GO:0005829; GO:0030316; GO:0030321; GO:0034707 12177 XM_029350372.2 3446 2219 2084 3140 1552 NA NA NA NA NA NA 12178 XM_029347536.2 253 212 122 322 331 NA NA NA NA NA NA 12179 XM_029333114.2 51 39 41 37 47 NA NA NA NA NA NA 12180 XM_044328148.1 0 0 134 38 0 O88974 1.05e-75 Histone-lysine N-methyltransferase SETDB1 (EC 2.1.1.366) (ERG-associated protein with SET domain) (ESET) (SET domain bifurcated 1) Mus musculus (Mouse) bone development [GO:0060348]; heterochromatin organization [GO:0070828]; histone H3-K9 methylation [GO:0051567]; inner cell mass cell proliferation [GO:0001833]; negative regulation of gene expression [GO:0010629]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA methylation-dependent heterochromatin formation [GO:0090309]; Ras protein signal transduction [GO:0007265] GO:0000122; GO:0001833; GO:0003677; GO:0003682; GO:0005634; GO:0005654; GO:0005694; GO:0005737; GO:0007265; GO:0008270; GO:0010629; GO:0018024; GO:0043231; GO:0045869; GO:0046974; GO:0051567; GO:0060348; GO:0070828; GO:0090309; GO:0140947; GO:0140948; GO:1990841 12181 XM_044328148.1 0 0 134 38 0 O88974 4.57e-46 Histone-lysine N-methyltransferase SETDB1 (EC 2.1.1.366) (ERG-associated protein with SET domain) (ESET) (SET domain bifurcated 1) Mus musculus (Mouse) bone development [GO:0060348]; heterochromatin organization [GO:0070828]; histone H3-K9 methylation [GO:0051567]; inner cell mass cell proliferation [GO:0001833]; negative regulation of gene expression [GO:0010629]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA methylation-dependent heterochromatin formation [GO:0090309]; Ras protein signal transduction [GO:0007265] GO:0000122; GO:0001833; GO:0003677; GO:0003682; GO:0005634; GO:0005654; GO:0005694; GO:0005737; GO:0007265; GO:0008270; GO:0010629; GO:0018024; GO:0043231; GO:0045869; GO:0046974; GO:0051567; GO:0060348; GO:0070828; GO:0090309; GO:0140947; GO:0140948; GO:1990841 12182 XM_044328148.1 0 0 134 38 0 O88974 4.06e-39 Histone-lysine N-methyltransferase SETDB1 (EC 2.1.1.366) (ERG-associated protein with SET domain) (ESET) (SET domain bifurcated 1) Mus musculus (Mouse) bone development [GO:0060348]; heterochromatin organization [GO:0070828]; histone H3-K9 methylation [GO:0051567]; inner cell mass cell proliferation [GO:0001833]; negative regulation of gene expression [GO:0010629]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA methylation-dependent heterochromatin formation [GO:0090309]; Ras protein signal transduction [GO:0007265] GO:0000122; GO:0001833; GO:0003677; GO:0003682; GO:0005634; GO:0005654; GO:0005694; GO:0005737; GO:0007265; GO:0008270; GO:0010629; GO:0018024; GO:0043231; GO:0045869; GO:0046974; GO:0051567; GO:0060348; GO:0070828; GO:0090309; GO:0140947; GO:0140948; GO:1990841 12183 XR_006393766.1 1 20 82 5 9 NA NA NA NA NA NA 12184 XM_029345001.2 1540 964 478 1476 1185 NA NA NA NA NA NA 12185 XM_029344214.2 1516 1319 869 1676 1550 Q9Z1Q9 0 Valine--tRNA ligase (EC 6.1.1.9) (Protein G7a) (Valyl-tRNA synthetase) (ValRS) Mus musculus (Mouse) valyl-tRNA aminoacylation [GO:0006438] GO:0002161; GO:0004832; GO:0005524; GO:0005739; GO:0005829; GO:0006438 12186 XM_029346158.2 81 72 56 43 179 Q9EPI9 0 Potassium voltage-gated channel subfamily H member 5 (Ether-a-go-go potassium channel 2) (rEAG2) (Voltage-gated potassium channel subunit Kv10.2) Rattus norvegicus (Rat) potassium ion transmembrane transport [GO:0071805]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391] GO:0005249; GO:0005516; GO:0005886; GO:0009986; GO:0010389; GO:0034765; GO:0042391; GO:0044325; GO:0044877; GO:0071805 12187 XM_044313049.1 5 0 4 0 10 NA NA NA NA NA NA 12188 XM_044318687.1 4249 7322 1462 6833 7828 A0A0R4IBK5 0 E3 ubiquitin-protein ligase rnf213-alpha (EC 2.3.2.27) (EC 3.6.4.-) (E3 ubiquitin-lipopolysaccharide ligase rnf213-alpha) (EC 2.3.2.-) (Mysterin-A) (Mysterin-alpha) (RING finger protein 213-A) (RING finger protein 213-alpha) Danio rerio (Zebrafish) (Brachydanio rerio) blood circulation [GO:0008015]; defense response to bacterium [GO:0042742]; immune system process [GO:0002376]; lipid droplet formation [GO:0140042]; lipid ubiquitination [GO:0120323]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein K63-linked ubiquitination [GO:0070534]; regulation of lipid metabolic process [GO:0019216]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]; xenophagy [GO:0098792] GO:0002040; GO:0002376; GO:0004842; GO:0005524; GO:0005730; GO:0005811; GO:0005829; GO:0006511; GO:0008015; GO:0016887; GO:0019216; GO:0042742; GO:0046872; GO:0061630; GO:0070534; GO:0098792; GO:0120323; GO:0140042; GO:2000051 12189 XM_044318687.1 4249 7322 1462 6833 7828 A0A0R4IBK5 1.35e-128 E3 ubiquitin-protein ligase rnf213-alpha (EC 2.3.2.27) (EC 3.6.4.-) (E3 ubiquitin-lipopolysaccharide ligase rnf213-alpha) (EC 2.3.2.-) (Mysterin-A) (Mysterin-alpha) (RING finger protein 213-A) (RING finger protein 213-alpha) Danio rerio (Zebrafish) (Brachydanio rerio) blood circulation [GO:0008015]; defense response to bacterium [GO:0042742]; immune system process [GO:0002376]; lipid droplet formation [GO:0140042]; lipid ubiquitination [GO:0120323]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein K63-linked ubiquitination [GO:0070534]; regulation of lipid metabolic process [GO:0019216]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]; xenophagy [GO:0098792] GO:0002040; GO:0002376; GO:0004842; GO:0005524; GO:0005730; GO:0005811; GO:0005829; GO:0006511; GO:0008015; GO:0016887; GO:0019216; GO:0042742; GO:0046872; GO:0061630; GO:0070534; GO:0098792; GO:0120323; GO:0140042; GO:2000051 12190 XM_044318687.1 4249 7322 1462 6833 7828 A0A0R4IBK5 6.38e-76 E3 ubiquitin-protein ligase rnf213-alpha (EC 2.3.2.27) (EC 3.6.4.-) (E3 ubiquitin-lipopolysaccharide ligase rnf213-alpha) (EC 2.3.2.-) (Mysterin-A) (Mysterin-alpha) (RING finger protein 213-A) (RING finger protein 213-alpha) Danio rerio (Zebrafish) (Brachydanio rerio) blood circulation [GO:0008015]; defense response to bacterium [GO:0042742]; immune system process [GO:0002376]; lipid droplet formation [GO:0140042]; lipid ubiquitination [GO:0120323]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein K63-linked ubiquitination [GO:0070534]; regulation of lipid metabolic process [GO:0019216]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]; xenophagy [GO:0098792] GO:0002040; GO:0002376; GO:0004842; GO:0005524; GO:0005730; GO:0005811; GO:0005829; GO:0006511; GO:0008015; GO:0016887; GO:0019216; GO:0042742; GO:0046872; GO:0061630; GO:0070534; GO:0098792; GO:0120323; GO:0140042; GO:2000051 12191 XM_044326909.1 8 3 10 0 3 NA NA NA NA NA NA 12192 XM_044328799.1 221 87 164 117 87 P09849 0 Lactase/phlorizin hydrolase (Lactase/glycosylceramidase) [Includes: Lactase (EC 3.2.1.108); Glycosylceramidase (EC 3.2.1.62) (Phlorizin hydrolase)] Oryctolagus cuniculus (Rabbit) cellobiose catabolic process [GO:2000892]; glycosylceramide catabolic process [GO:0046477]; lactose catabolic process [GO:0005990]; quercetin catabolic process [GO:1901733] GO:0000016; GO:0004336; GO:0004348; GO:0005990; GO:0008422; GO:0017042; GO:0042803; GO:0046477; GO:0080079; GO:0098591; GO:0140749; GO:1901733; GO:2000892 12193 XM_044328799.1 221 87 164 117 87 P09849 0 Lactase/phlorizin hydrolase (Lactase/glycosylceramidase) [Includes: Lactase (EC 3.2.1.108); Glycosylceramidase (EC 3.2.1.62) (Phlorizin hydrolase)] Oryctolagus cuniculus (Rabbit) cellobiose catabolic process [GO:2000892]; glycosylceramide catabolic process [GO:0046477]; lactose catabolic process [GO:0005990]; quercetin catabolic process [GO:1901733] GO:0000016; GO:0004336; GO:0004348; GO:0005990; GO:0008422; GO:0017042; GO:0042803; GO:0046477; GO:0080079; GO:0098591; GO:0140749; GO:1901733; GO:2000892 12194 XR_006394543.1 773 735 786 1749 1072 P70627 1.42e-114 Glutamate carboxypeptidase 2 (EC 3.4.17.21) (Folate hydrolase 1) (Folylpoly-gamma-glutamate carboxypeptidase) (FGCP) (Glutamate carboxypeptidase II) (GCPII) (Membrane glutamate carboxypeptidase) (mGCP) (N-acetylated-alpha-linked acidic dipeptidase I) (NAALADase I) (Prostate-specific membrane antigen homolog) (Pteroylpoly-gamma-glutamate carboxypeptidase) Rattus norvegicus (Rat) C-terminal protein deglutamylation [GO:0035609]; folic acid-containing compound metabolic process [GO:0006760]; positive regulation of apoptotic process [GO:0043065]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508] GO:0004180; GO:0004181; GO:0005886; GO:0006508; GO:0006760; GO:0008233; GO:0009986; GO:0016020; GO:0016805; GO:0030163; GO:0035609; GO:0043065; GO:0046872; GO:1904492; GO:1904493 12195 XM_029324987.2 209 305 127 249 358 NA NA NA NA NA NA 12196 XM_044326519.1 0 20 0 0 0 NA NA NA NA NA NA 12197 XM_044316647.1 56 34 34 22 64 P56718 4.56e-27 Orexin/Hypocretin receptor type 1 (Hypocretin receptor type 1) (Orexin receptor type 1) (Ox-1-R) (Ox1-R) (Ox1R) Rattus norvegicus (Rat) feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0004930; GO:0005886; GO:0007186; GO:0007218; GO:0007631; GO:0016499; GO:0017046; GO:0051480; GO:0070374 12198 XM_029343480.2 0 0 10 0 36 NA NA NA NA NA NA 12199 XM_029354759.2 769 828 631 828 1419 Q9EQC4 1.32e-72 Elongation of very long chain fatty acids protein 4 (EC 2.3.1.199) (3-keto acyl-CoA synthase Elovl4) (ELOVL fatty acid elongase 4) (ELOVL FA elongase 4) (Very long chain 3-ketoacyl-CoA synthase 4) (Very long chain 3-oxoacyl-CoA synthase 4) Mus musculus (Mouse) fatty acid elongation, monounsaturated fatty acid [GO:0034625]; fatty acid elongation, polyunsaturated fatty acid [GO:0034626]; fatty acid elongation, saturated fatty acid [GO:0019367]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; sphingolipid biosynthetic process [GO:0030148]; unsaturated fatty acid biosynthetic process [GO:0006636]; very long-chain fatty acid biosynthetic process [GO:0042761] GO:0005783; GO:0005789; GO:0006636; GO:0009922; GO:0019367; GO:0030148; GO:0034625; GO:0034626; GO:0035338; GO:0042761; GO:0102756 12200 XM_044323253.1 52 0 0 0 20 O73792 7.84e-53 Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1) Danio rerio (Zebrafish) (Brachydanio rerio) angiogenesis [GO:0001525]; blood vessel development [GO:0001568]; endothelial cell-cell adhesion [GO:0071603]; heart development [GO:0007507]; positive regulation of angiogenesis [GO:0045766]; positive regulation of kinase activity [GO:0033674]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculature development [GO:0001944] GO:0001525; GO:0001568; GO:0001944; GO:0004714; GO:0005524; GO:0005886; GO:0007169; GO:0007507; GO:0033674; GO:0043235; GO:0045766; GO:0071603 12201 XM_044326363.1 12 13 13 1 17 NA NA NA NA NA NA 12202 XM_029332431.2 111 27 14 57 32 NA NA NA NA NA NA 12203 XM_044327888.1 0 23 0 24 0 NA NA NA NA NA NA 12204 XM_029343264.2 229 84 77 165 229 Q96AN5 4.46e-44 Transmembrane protein 143 Homo sapiens (Human) NA GO:0005739; GO:0016020 12205 XM_029335607.2 327 161 150 299 250 NA NA NA NA NA NA 12206 XM_044307898.1 9 6 28 0 21 NA NA NA NA NA NA 12207 XM_044311716.1 0 0 23 0 0 A1L0Y2 1.47e-30 Neuralized-like protein 4 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737; GO:0005814 12208 XM_044311716.1 0 0 23 0 0 A1L0Y2 1.47e-30 Neuralized-like protein 4 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737; GO:0005814 12209 XM_044311716.1 0 0 23 0 0 A1L0Y2 5.6e-25 Neuralized-like protein 4 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737; GO:0005814 12210 XM_044311716.1 0 0 23 0 0 A1L0Y2 5.6e-25 Neuralized-like protein 4 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737; GO:0005814 12211 XM_044311716.1 0 0 23 0 0 A1L0Y2 1.89e-22 Neuralized-like protein 4 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737; GO:0005814 12212 XM_044311716.1 0 0 23 0 0 A1L0Y2 1.89e-22 Neuralized-like protein 4 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737; GO:0005814 12213 XM_044311716.1 0 0 23 0 0 A1L0Y2 4.74e-21 Neuralized-like protein 4 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737; GO:0005814 12214 XM_044311716.1 0 0 23 0 0 A1L0Y2 4.74e-21 Neuralized-like protein 4 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737; GO:0005814 12215 XR_003826554.2 4987 3547 3857 2100 2709 Q9DAJ5 5.82e-30 Dynein light chain roadblock-type 2 (Dynein light chain 2B, cytoplasmic) Mus musculus (Mouse) microtubule-based movement [GO:0007018] GO:0005737; GO:0005813; GO:0005868; GO:0005874; GO:0007018; GO:0045505 12216 XM_029331784.2 839 568 521 657 902 NA NA NA NA NA NA 12217 XM_044317233.1 438 258 200 445 176 Q94887 1.07e-32 Neurexin-4 (Neurexin IV) Drosophila melanogaster (Fruit fly) axon ensheathment [GO:0008366]; cell adhesion involved in heart morphogenesis [GO:0061343]; cell-cell junction organization [GO:0045216]; dorsal closure [GO:0007391]; establishment of glial blood-brain barrier [GO:0060857]; heart process [GO:0003015]; nerve maturation [GO:0021682]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]; synaptic target recognition [GO:0008039]; terminal button organization [GO:0072553] GO:0003015; GO:0005886; GO:0005919; GO:0007391; GO:0008039; GO:0008104; GO:0008366; GO:0019991; GO:0021682; GO:0035151; GO:0045202; GO:0045216; GO:0048786; GO:0060857; GO:0061343; GO:0072553; GO:0097105 12218 XR_003825283.2 8 2 10 0 30 NA NA NA NA NA NA 12219 XM_044324701.1 34 0 0 5 0 NA NA NA NA NA NA 12220 XM_029333998.2 0 0 23 2 6 NA NA NA NA NA NA 12221 XM_044323803.1 262 356 339 380 533 Q2EMV9 8.62e-148 Protein mono-ADP-ribosyltransferase PARP14 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (Collaborator of STAT6) (CoaSt6) (Poly [ADP-ribose] polymerase 14) (PARP-14) Mus musculus (Mouse) innate immune response [GO:0045087]; negative regulation of gene expression [GO:0010629]; negative regulation of type II interferon-mediated signaling pathway [GO:0060336]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; positive regulation of interleukin-4-mediated signaling pathway [GO:1902216]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein poly-ADP-ribosylation [GO:0070212] GO:0003714; GO:0003950; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0010629; GO:0016779; GO:0019899; GO:0042531; GO:0042532; GO:0045087; GO:0060336; GO:0070212; GO:0070403; GO:1902216; GO:1990404 12222 XM_029337531.2 23 38 130 37 93 Q9YHV3 5.57e-33 Noggin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cartilage development [GO:0051216]; cloaca development [GO:0035844]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic viscerocranium morphogenesis [GO:0048703]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell differentiation [GO:0045596]; osteoblast differentiation [GO:0001649]; pronephros development [GO:0048793] GO:0001649; GO:0005615; GO:0007368; GO:0009953; GO:0030514; GO:0035844; GO:0045596; GO:0048703; GO:0048793; GO:0051216 12223 XM_044321455.1 0 95 0 0 0 O43900 2.41e-130 Prickle planar cell polarity protein 3 (LIM domain only protein 6) (LMO-6) (Prickle-like protein 3) (Pk3) (Triple LIM domain protein 6) Homo sapiens (Human) cell projection organization [GO:0030030] GO:0005739; GO:0005886; GO:0008270; GO:0030030 12224 XM_044328899.1 6 0 0 0 0 Q7TN88 9.27e-92 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 12225 XM_044309611.1 8 4 2 4 9 NA NA NA NA NA NA 12226 XM_044322635.1 3 44 3 41 110 P0CT40 4.24e-64 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 12227 XM_044328079.1 0 0 0 0 6 Q3B8H3 4.48e-70 Transmembrane protein 11-B, mitochondrial Xenopus laevis (African clawed frog) mitochondrion organization [GO:0007005] GO:0005743; GO:0007005 12228 XM_044310609.1 2850 2231 1412 2200 2147 NA NA NA NA NA NA 12229 XM_044309932.1 305 159 203 309 562 Q8CE13 8.36e-26 Coiled-coil domain-containing protein 17 Mus musculus (Mouse) NA NA 12230 XM_029339145.2 11 0 42 0 0 NA NA NA NA NA NA 12231 XM_029339523.2 74 44 38 64 61 NA NA NA NA NA NA 12232 XM_044322309.1 59 48 25 51 63 NA NA NA NA NA NA 12233 XM_029355979.2 10 17 61 0 53 NA NA NA NA NA NA 12234 XM_044328382.1 56 0 8 7 11 NA NA NA NA NA NA 12235 XM_029341150.2 424 435 213 564 324 NA NA NA NA NA NA 12236 XM_044320919.1 0 0 0 7 66 Q9VBW3 4.97e-42 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 12237 XM_029350745.2 900 706 479 847 899 Q6PAV2 0 Probable E3 ubiquitin-protein ligase HERC4 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 4) (HECT-type E3 ubiquitin transferase HERC4) Mus musculus (Mouse) cell differentiation [GO:0030154]; negative regulation of smoothened signaling pathway [GO:0045879]; protein ubiquitination [GO:0016567]; spermatogenesis [GO:0007283]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0001650; GO:0004842; GO:0005737; GO:0005829; GO:0006511; GO:0007283; GO:0016567; GO:0030154; GO:0045879; GO:0061630 12238 XM_029349666.2 1756 1245 1268 1076 616 A7RFT2 3.4e-137 Cell division cycle protein 123 homolog Nematostella vectensis (Starlet sea anemone) cell cycle [GO:0007049]; cell division [GO:0051301] GO:0005737; GO:0007049; GO:0051301 12239 XR_006397275.1 0 0 15 10 14 Q80TR8 0 DDB1- and CUL4-associated factor 1 (Serine/threonine-protein kinase VPRBP) (EC 2.7.11.1) Mus musculus (Mouse) B cell differentiation [GO:0030183]; cell competition in a multicellular organism [GO:0035212]; chromatin organization [GO:0006325]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phosphorylation [GO:0016310]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; V(D)J recombination [GO:0033151] GO:0000122; GO:0001650; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0006325; GO:0008180; GO:0016310; GO:0016567; GO:0030183; GO:0030331; GO:0033151; GO:0035212; GO:0043687; GO:0080008; GO:0106310; GO:1990244 12240 XR_006397275.1 0 0 15 10 14 Q80TR8 2.87e-98 DDB1- and CUL4-associated factor 1 (Serine/threonine-protein kinase VPRBP) (EC 2.7.11.1) Mus musculus (Mouse) B cell differentiation [GO:0030183]; cell competition in a multicellular organism [GO:0035212]; chromatin organization [GO:0006325]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phosphorylation [GO:0016310]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; V(D)J recombination [GO:0033151] GO:0000122; GO:0001650; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0006325; GO:0008180; GO:0016310; GO:0016567; GO:0030183; GO:0030331; GO:0033151; GO:0035212; GO:0043687; GO:0080008; GO:0106310; GO:1990244 12241 XR_006393646.1 102 6476 14453 8092 5750 NA NA NA NA NA NA 12242 XM_029340550.2 1055 989 810 884 866 A0A452G813 6.86e-142 CSC1-like protein 1 (Transmembrane protein 63A) Capra hircus (Goat) regulation of cytokine production [GO:0001817]; regulation of mononuclear cell proliferation [GO:0032944]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of phagocytosis [GO:0050764] GO:0001817; GO:0003676; GO:0005227; GO:0005765; GO:0005886; GO:0032944; GO:0045428; GO:0050764; GO:1990760 12243 XM_029351660.2 82 86 66 125 117 Q7T312 8.42e-69 Coiled-coil domain-containing protein 25 Danio rerio (Zebrafish) (Brachydanio rerio) positive regulation of cell motility [GO:2000147] GO:0003677; GO:0005886; GO:0012505; GO:2000147 12244 XM_029356046.2 109 125 101 165 60 O73888 1.86e-34 Hematopoietic prostaglandin D synthase (H-PGDS) (EC 5.3.99.2) (GST class-sigma) (Glutathione S-transferase) (EC 2.5.1.18) (Glutathione-dependent PGD synthase) (Glutathione-requiring prostaglandin D synthase) (Prostaglandin-H2 D-isomerase) Gallus gallus (Chicken) glutathione metabolic process [GO:0006749]; prostaglandin biosynthetic process [GO:0001516]; prostaglandin metabolic process [GO:0006693] GO:0000287; GO:0001516; GO:0004364; GO:0004667; GO:0005509; GO:0005737; GO:0006693; GO:0006749 12245 XR_006396148.1 2401 1148 4271 2272 4564 Q9WU63 5.51e-31 Heme-binding protein 2 (Protein SOUL) Mus musculus (Mouse) negative regulation of mitochondrial membrane potential [GO:0010917]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of necrotic cell death [GO:0010940] GO:0005737; GO:0005739; GO:0010917; GO:0010940; GO:0020037; GO:0035794 12246 XR_006396148.1 2401 1148 4271 2272 4564 Q9WU63 9.55e-25 Heme-binding protein 2 (Protein SOUL) Mus musculus (Mouse) negative regulation of mitochondrial membrane potential [GO:0010917]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of necrotic cell death [GO:0010940] GO:0005737; GO:0005739; GO:0010917; GO:0010940; GO:0020037; GO:0035794 12247 XM_044319514.1 2 0 11 0 5 NA NA NA NA NA NA 12248 XM_044308273.1 342 113 124 79 99 Q5XGM3 4.6e-154 Betaine--homocysteine S-methyltransferase 1 (EC 2.1.1.5) Xenopus laevis (African clawed frog) amino-acid betaine catabolic process [GO:0006579]; methionine biosynthetic process [GO:0009086]; methylation [GO:0032259] GO:0005737; GO:0006579; GO:0008270; GO:0009086; GO:0032259; GO:0047150 12249 XM_044315556.1 5 5 1 16 21 NA NA NA NA NA NA 12250 XM_029355338.2 275 118 33 104 100 Q14AT5 0 Anoctamin-7 (New gene expressed in prostate homolog) (Transmembrane protein 16G) Mus musculus (Mouse) calcium activated galactosylceramide scrambling [GO:0061591]; calcium activated phosphatidylcholine scrambling [GO:0061590]; calcium activated phosphatidylserine scrambling [GO:0061589]; calcium activated phospholipid scrambling [GO:0061588]; chloride transmembrane transport [GO:1902476]; chloride transport [GO:0006821]; establishment of localization in cell [GO:0051649]; transmembrane transport [GO:0055085] GO:0005254; GO:0005783; GO:0005886; GO:0006821; GO:0017128; GO:0046983; GO:0051649; GO:0055085; GO:0061588; GO:0061589; GO:0061590; GO:0061591; GO:1902476 12251 XR_006394173.1 211 7 11 354 90 NA NA NA NA NA NA 12252 XM_029335886.2 45 39 32 45 0 Q07066 1.14e-36 Peroxisomal membrane protein 2 (22 kDa peroxisomal membrane protein) Rattus norvegicus (Rat) NA GO:0005737; GO:0005739; GO:0005777; GO:0005778; GO:0032991 12253 XM_029358756.2 853 478 629 1025 1218 NA NA NA NA NA NA 12254 XR_006394847.1 924 1191 798 1090 714 O93429 3e-57 Serotransferrin Paralichthys olivaceus (Bastard halibut) (Hippoglossus olivaceus) ion transport [GO:0006811]; iron ion homeostasis [GO:0055072] GO:0005615; GO:0006811; GO:0046872; GO:0055072 12255 XR_006394847.1 924 1191 798 1090 714 O93429 3e-57 Serotransferrin Paralichthys olivaceus (Bastard halibut) (Hippoglossus olivaceus) ion transport [GO:0006811]; iron ion homeostasis [GO:0055072] GO:0005615; GO:0006811; GO:0046872; GO:0055072 12256 XR_006394847.1 924 1191 798 1090 714 O93429 7.88e-37 Serotransferrin Paralichthys olivaceus (Bastard halibut) (Hippoglossus olivaceus) ion transport [GO:0006811]; iron ion homeostasis [GO:0055072] GO:0005615; GO:0006811; GO:0046872; GO:0055072 12257 XR_006394847.1 924 1191 798 1090 714 O93429 7.88e-37 Serotransferrin Paralichthys olivaceus (Bastard halibut) (Hippoglossus olivaceus) ion transport [GO:0006811]; iron ion homeostasis [GO:0055072] GO:0005615; GO:0006811; GO:0046872; GO:0055072 12258 XM_029330074.2 92 77 25 41 82 Q16445 1.23e-62 Gamma-aminobutyric acid receptor subunit alpha-6 (GABA(A) receptor subunit alpha-6) Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid signaling pathway [GO:0007214]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; regulation of postsynaptic membrane potential [GO:0060078]; signal transduction [GO:0007165]; synaptic transmission, GABAergic [GO:0051932] GO:0004890; GO:0005231; GO:0005237; GO:0005886; GO:0007165; GO:0007214; GO:0007268; GO:0008503; GO:0022851; GO:0030594; GO:0032590; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051932; GO:0060078; GO:0098794; GO:0099192; GO:1902476; GO:1902711; GO:1904315 12259 XM_044321147.1 0 0 0 0 83 Q9NYT0 1.29e-45 Pleckstrin-2 Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; intracellular signal transduction [GO:0035556]; positive regulation of plasma membrane bounded cell projection assembly [GO:0120034] GO:0005737; GO:0005856; GO:0005886; GO:0031258; GO:0031532; GO:0032266; GO:0035556; GO:0043325; GO:0080025; GO:0120034 12260 XR_006396024.1 414 169 179 269 373 Q23915 1.13e-22 Probable serine/threonine-protein kinase kinX (EC 2.7.11.1) Dictyostelium discoideum (Social amoeba) protein phosphorylation [GO:0006468]; signal transduction [GO:0007165] GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0006468; GO:0007165; GO:0106310 12261 XM_044309898.1 425 659 258 858 3095 NA NA NA NA NA NA 12262 XM_029351287.2 2523 1517 790 994 1426 Q0VCJ8 2.67e-89 Protein-L-histidine N-pros-methyltransferase (EC 2.1.1.-) (Methyltransferase-like protein 9) Bos taurus (Bovine) NA GO:0005739; GO:0005783; GO:0106370 12263 XM_044327757.1 3 17 15 20 23 NA NA NA NA NA NA 12264 XM_044310431.1 36 6 25 1 99 P06803 1.59e-51 Serine/threonine-protein kinase pim-1 (EC 2.7.11.1) Mus musculus (Mouse) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cellular detoxification [GO:1990748]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cardioblast proliferation [GO:1905062]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of transmembrane transporter activity [GO:0022898]; vitamin D receptor signaling pathway [GO:0070561] GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0005886; GO:0006468; GO:0006915; GO:0007049; GO:0022898; GO:0030145; GO:0043024; GO:0043066; GO:0043433; GO:0043539; GO:0045737; GO:0045893; GO:0046777; GO:0050821; GO:0060045; GO:0070561; GO:0071902; GO:0090336; GO:0106310; GO:1902033; GO:1905062; GO:1990748 12265 XR_006391577.1 39 2 16 12 66 NA NA NA NA NA NA 12266 XR_006395865.1 34 2 0 2 9 NA NA NA NA NA NA 12267 XM_029336680.2 952 577 643 1169 1057 NA NA NA NA NA NA 12268 XM_044323862.1 433 271 423 260 0 Q6NVY1 3.18e-143 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial (EC 3.1.2.4) (3-hydroxyisobutyryl-coenzyme A hydrolase) (HIB-CoA hydrolase) (HIBYL-CoA-H) Homo sapiens (Human) branched-chain amino acid catabolic process [GO:0009083]; valine catabolic process [GO:0006574] GO:0003860; GO:0005739; GO:0005759; GO:0006574; GO:0009083 12269 XM_029342541.2 0 12 0 0 14 Q9EQD2 1.72e-33 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 12270 XR_006394842.1 1 1 1 5 18 NA NA NA NA NA NA 12271 XM_044321853.1 535 319 347 404 634 NA NA NA NA NA NA 12272 XR_003824603.2 0 8 3 0 0 NA NA NA NA NA NA 12273 XM_044313718.1 13 0 0 1 14 Q9VBW3 2.14e-58 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 12274 XM_044314913.1 327 186 107 155 150 NA NA NA NA NA NA 12275 XM_044310698.1 153 0 85 211 3 B3EWZ8 1.2e-24 Ectin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 12276 XM_029341472.2 1500 1520 1530 1675 1598 Q5FVR2 7.21e-112 Thymidine phosphorylase (TP) (EC 2.4.2.4) (TdRPase) Rattus norvegicus (Rat) dTMP catabolic process [GO:0046074]; mitochondrial genome maintenance [GO:0000002]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside metabolic process [GO:0006213]; regulation of gastric motility [GO:1905333]; regulation of myelination [GO:0031641]; regulation of transmission of nerve impulse [GO:0051969] GO:0000002; GO:0004645; GO:0005829; GO:0006206; GO:0006213; GO:0009032; GO:0016154; GO:0031641; GO:0042803; GO:0046074; GO:0051969; GO:1905333 12277 XM_029356811.2 0 196 205 104 373 NA NA NA NA NA NA 12278 XR_006393649.1 51 444 732 274 193 NA NA NA NA NA NA 12279 XM_029328880.2 2725 2259 1854 2647 1308 A7MB63 2.44e-110 Cystinosin Bos taurus (Bovine) L-cystine transport [GO:0015811]; melanin biosynthetic process [GO:0042438]; protein transport [GO:0015031]; regulation of melanin biosynthetic process [GO:0048021] GO:0005765; GO:0005774; GO:0015031; GO:0015184; GO:0015295; GO:0015811; GO:0033162; GO:0042438; GO:0042470; GO:0048021 12280 XM_044314382.1 5 1 0 0 20 NA NA NA NA NA NA 12281 XM_044323497.1 88 250 34 383 86 NA NA NA NA NA NA 12282 XM_044321289.1 3614 2336 4430 2047 5750 P0CT39 1.3e-68 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 12283 XM_044309407.1 115 184 106 170 132 NA NA NA NA NA NA 12284 XM_044318196.1 7 6 182 5 71 NA NA NA NA NA NA 12285 XM_029357741.2 1588 758 1115 1111 1087 Q6GMK8 1.45e-173 Mannose-1-phosphate guanyltransferase alpha-A (EC 2.7.7.13) (GDP-mannose pyrophosphorylase A-A) (GTP-mannose-1-phosphate guanylyltransferase subunit alpha-A) Danio rerio (Zebrafish) (Brachydanio rerio) GDP-mannose biosynthetic process [GO:0009298] GO:0004475; GO:0005525; GO:0005737; GO:0009298 12286 XM_044318561.1 46 0 43 151 0 Q68F72 1.05e-82 Solute carrier family 15 member 4 Xenopus laevis (African clawed frog) dipeptide import across plasma membrane [GO:0140206]; innate immune response [GO:0045087]; mast cell homeostasis [GO:0033023]; peptidoglycan transport [GO:0015835]; positive regulation of innate immune response [GO:0045089]; positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [GO:0070430]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of toll-like receptor 7 signaling pathway [GO:0034157]; positive regulation of toll-like receptor 8 signaling pathway [GO:0034161]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; protein transport [GO:0015031]; regulation of isotype switching to IgG isotypes [GO:0048302]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424] GO:0005290; GO:0005765; GO:0015031; GO:0015333; GO:0015647; GO:0015835; GO:0031901; GO:0033023; GO:0034157; GO:0034161; GO:0034165; GO:0036020; GO:0045087; GO:0045089; GO:0048302; GO:0070424; GO:0070430; GO:0070434; GO:0071916; GO:0140206 12287 XM_029344529.2 10 0 0 5 11 NA NA NA NA NA NA 12288 XM_029324526.2 3657 3222 3634 4346 3222 Q0V9J5 1.2e-41 Probable RNA-binding protein EIF1AD (Eukaryotic translation initiation factor 1A domain-containing protein) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0003723; GO:0003743; GO:0005634 12289 XM_029346040.2 5 0 3 3 35 Q29RU2 1.13e-26 Oncoprotein-induced transcript 3 protein Bos taurus (Bovine) NA GO:0005509; GO:0005635 12290 XM_029346040.2 5 0 3 3 35 Q29RU2 9.28e-21 Oncoprotein-induced transcript 3 protein Bos taurus (Bovine) NA GO:0005509; GO:0005635 12291 XM_044325288.1 490 822 364 743 424 E1BKH1 0 EF-hand domain-containing protein 1 (Myoclonin-1) Bos taurus (Bovine) cerebral cortex cell migration [GO:0021795]; cilium-dependent cell motility [GO:0060285]; mitotic cytokinesis [GO:0000281]; mitotic spindle organization [GO:0007052]; regulation of cell division [GO:0051302] GO:0000281; GO:0000922; GO:0005509; GO:0005813; GO:0005879; GO:0005930; GO:0007052; GO:0021795; GO:0043014; GO:0051302; GO:0060285; GO:0072686 12292 XR_006391991.1 4 9 0 0 17 NA NA NA NA NA NA 12293 XM_044313827.1 10 34 279 211 94 NA NA NA NA NA NA 12294 XR_006394701.1 279 11 122 217 103 NA NA NA NA NA NA 12295 XR_006393990.1 0 7 0 4 2 NA NA NA NA NA NA 12296 XM_044312093.1 23 154 0 0 17 Q99MW1 6.41e-30 Serine/threonine-protein kinase 31 (EC 2.7.11.1) Mus musculus (Mouse) protein phosphorylation [GO:0006468] GO:0001669; GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0006468; GO:0106310 12297 XR_006394046.1 400 187 480 125 1256 NA NA NA NA NA NA 12298 XM_044323791.1 121 1 23 22 24 Q9VL06 5.9e-21 E3 ubiquitin-protein ligase Ufd4 (EC 2.3.2.26) (Ubiquitin fusion-degradation 4-like) Drosophila melanogaster (Fruit fly) anatomical structure development [GO:0048856]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000209; GO:0005634; GO:0006511; GO:0016607; GO:0032436; GO:0043161; GO:0046872; GO:0048856; GO:0061630; GO:0070373; GO:0070534 12299 XR_006393299.1 10 0 4 0 12 NA NA NA NA NA NA 12300 XM_044316517.1 36 26 45 70 178 P24524 2.02e-71 Glycine receptor subunit alpha-3 Rattus norvegicus (Rat) cellular response to amino acid stimulus [GO:0071230]; cellular response to ethanol [GO:0071361]; cellular response to zinc ion [GO:0071294]; chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; neuropeptide signaling pathway [GO:0007218]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; protein homooligomerization [GO:0051260]; regulation of membrane potential [GO:0042391]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amino acid [GO:0043200]; signal transduction [GO:0007165]; synaptic transmission, glycinergic [GO:0060012] GO:0004888; GO:0005231; GO:0005886; GO:0007165; GO:0007218; GO:0007268; GO:0016594; GO:0016934; GO:0016935; GO:0022852; GO:0030425; GO:0030594; GO:0034220; GO:0042391; GO:0042734; GO:0043005; GO:0043200; GO:0043204; GO:0045202; GO:0046872; GO:0050877; GO:0051260; GO:0060012; GO:0071230; GO:0071294; GO:0071361; GO:0098690; GO:0098793; GO:0098978; GO:0098982; GO:0099171; GO:0099634; GO:1902476; GO:1904315; GO:2000300 12301 XM_044316517.1 36 26 45 70 178 P24524 3.68e-68 Glycine receptor subunit alpha-3 Rattus norvegicus (Rat) cellular response to amino acid stimulus [GO:0071230]; cellular response to ethanol [GO:0071361]; cellular response to zinc ion [GO:0071294]; chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; neuropeptide signaling pathway [GO:0007218]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; protein homooligomerization [GO:0051260]; regulation of membrane potential [GO:0042391]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amino acid [GO:0043200]; signal transduction [GO:0007165]; synaptic transmission, glycinergic [GO:0060012] GO:0004888; GO:0005231; GO:0005886; GO:0007165; GO:0007218; GO:0007268; GO:0016594; GO:0016934; GO:0016935; GO:0022852; GO:0030425; GO:0030594; GO:0034220; GO:0042391; GO:0042734; GO:0043005; GO:0043200; GO:0043204; GO:0045202; GO:0046872; GO:0050877; GO:0051260; GO:0060012; GO:0071230; GO:0071294; GO:0071361; GO:0098690; GO:0098793; GO:0098978; GO:0098982; GO:0099171; GO:0099634; GO:1902476; GO:1904315; GO:2000300 12302 XM_029335478.2 211 114 182 120 209 NA NA NA NA NA NA 12303 XM_044318644.1 0 0 0 0 58 Q9BQS2 8.65e-35 Synaptotagmin-15 (Chr10Syt) (Synaptotagmin XV) (SytXV) Homo sapiens (Human) calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; vesicle-mediated transport [GO:0016192] GO:0000149; GO:0001786; GO:0005509; GO:0005544; GO:0005886; GO:0014059; GO:0016192; GO:0017156; GO:0017158; GO:0030276; GO:0070382; GO:0071277 12304 XR_006392014.1 41 2 0 71 42 NA NA NA NA NA NA 12305 XM_029334418.2 719 253 476 434 796 Q6DKN2 4.63e-34 Homeobox protein OTX2-B (xOTX2-B) (Orthodenticle 2-B) (Orthodenticle-A-like protein B) Xenopus laevis (African clawed frog) NA GO:0000981; GO:0003677; GO:0005634 12306 XM_029356663.2 46 5 7 24 20 NA NA NA NA NA NA 12307 XM_029328990.2 92 102 63 354 108 NA NA NA NA NA NA 12308 XM_044316964.1 348 184 61 148 155 NA NA NA NA NA NA 12309 XM_044319612.1 0 0 44 0 0 Q9DBQ7 1.89e-88 Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin-binding protein PACE-1) (SCY1-like protein 3) Mus musculus (Mouse) inflammatory response [GO:0006954]; neuron development [GO:0048666]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; spinal cord motor neuron differentiation [GO:0021522] GO:0000139; GO:0004672; GO:0005524; GO:0005737; GO:0005794; GO:0006468; GO:0006954; GO:0008104; GO:0021522; GO:0030027; GO:0042802; GO:0048666 12310 XM_044317160.1 1321 540 625 1753 927 O14841 0 5-oxoprolinase (EC 3.5.2.9) (5-oxo-L-prolinase) (5-OPase) (Pyroglutamase) Homo sapiens (Human) glutathione metabolic process [GO:0006749] GO:0005524; GO:0005829; GO:0006749; GO:0017168; GO:0042802 12311 XM_044310914.1 85 169 73 1 47 NA NA NA NA NA NA 12312 XM_029351663.2 0 0 52 0 34 Q9UJT9 1.08e-98 F-box/LRR-repeat protein 7 (F-box and leucine-rich repeat protein 7) (F-box protein FBL6/FBL7) Homo sapiens (Human) cell division [GO:0051301]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic cell cycle [GO:0000278]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000086; GO:0000151; GO:0000209; GO:0000278; GO:0005813; GO:0005829; GO:0006511; GO:0016567; GO:0019005; GO:0031146; GO:0051301 12313 XM_029340464.2 889 549 405 523 981 O13067 9.12e-122 Condensin complex subunit 2 (Barren homolog) (Chromosome assembly protein xCAP-H) (Chromosome-associated protein H) (Non-SMC condensin I complex subunit H) Xenopus laevis (African clawed frog) cell division [GO:0051301]; mitotic chromosome condensation [GO:0007076] GO:0000796; GO:0005634; GO:0005829; GO:0007076; GO:0051301 12314 XR_003828626.2 1 1 8 5 2 NA NA NA NA NA NA 12315 XM_029340278.2 0 0 18 88 30 Q5RA50 1.59e-26 Protein FAM124A Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA NA 12316 XM_029346065.2 463 592 251 507 415 NA NA NA NA NA NA 12317 XM_029331167.2 159 6 124 178 235 Q61212 9.85e-22 Neuropeptide Y receptor type 6 (NPY6-R) (Pancreatic polypeptide receptor 2) (PP2) Mus musculus (Mouse) NA GO:0001601; GO:0004983; GO:0005886; GO:0008188; GO:0042923; GO:0043005 12318 XM_044316220.1 1809 863 891 945 1597 A2RRV3 3.22e-48 Protein PAT1 homolog 1 (PAT1-like protein 1) (Protein PAT1 homolog b) (Pat1b) Danio rerio (Zebrafish) (Brachydanio rerio) deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; P-body assembly [GO:0033962] GO:0000290; GO:0000932; GO:0003723; GO:0016605; GO:0016607; GO:0033962 12319 XM_044317849.1 0 0 469 986 17 Q6NS15 5.22e-47 Mediator of RNA polymerase II transcription subunit 15 (Activator-recruited cofactor 105 kDa component) (ARC105) (xARC105) (Mediator complex subunit 15) Xenopus laevis (African clawed frog) positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0003712; GO:0005737; GO:0016592; GO:0045944 12320 XM_029337064.2 13 18 19 114 107 NA NA NA NA NA NA 12321 XM_029350194.2 0 96 182 82 0 NA NA NA NA NA NA 12322 XM_044319361.1 7 3 12 1 9 NA NA NA NA NA NA 12323 XM_029341278.2 0 0 0 6 0 NA NA NA NA NA NA 12324 XM_029356002.2 263 169 122 204 315 P82923 8.15e-74 28S ribosomal protein S2, mitochondrial (MRP-S2) (S2mt) Bos taurus (Bovine) mitochondrial ribosome assembly [GO:0061668]; mitochondrial translation [GO:0032543] GO:0003735; GO:0005743; GO:0005763; GO:0032543; GO:0061668 12325 XM_044307684.1 401 397 0 265 0 NA NA NA NA NA NA 12326 XM_029336681.2 2139 2359 1276 1985 1396 F1RWC3 3.94e-27 Cubilin (Intrinsic factor-cobalamin receptor) Sus scrofa (Pig) cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031] GO:0005509; GO:0005765; GO:0005768; GO:0005905; GO:0008203; GO:0015031; GO:0016324; GO:0031419 12327 XM_029336681.2 2139 2359 1276 1985 1396 F1RWC3 3.32e-25 Cubilin (Intrinsic factor-cobalamin receptor) Sus scrofa (Pig) cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031] GO:0005509; GO:0005765; GO:0005768; GO:0005905; GO:0008203; GO:0015031; GO:0016324; GO:0031419 12328 XM_029336681.2 2139 2359 1276 1985 1396 F1RWC3 1.85e-22 Cubilin (Intrinsic factor-cobalamin receptor) Sus scrofa (Pig) cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031] GO:0005509; GO:0005765; GO:0005768; GO:0005905; GO:0008203; GO:0015031; GO:0016324; GO:0031419 12329 XM_029336681.2 2139 2359 1276 1985 1396 F1RWC3 2.1e-21 Cubilin (Intrinsic factor-cobalamin receptor) Sus scrofa (Pig) cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031] GO:0005509; GO:0005765; GO:0005768; GO:0005905; GO:0008203; GO:0015031; GO:0016324; GO:0031419 12330 XM_044321926.1 2 6 8 1 5 NA NA NA NA NA NA 12331 XM_029357983.2 1672 1438 1382 1539 1752 Q8BWT1 2.42e-180 3-ketoacyl-CoA thiolase, mitochondrial (EC 2.3.1.16) (Acetyl-CoA acetyltransferase) (EC 2.3.1.9) (Acetyl-CoA acyltransferase) (Acyl-CoA hydrolase, mitochondrial) (EC 3.1.2.-, EC 3.1.2.1, EC 3.1.2.2) (Beta-ketothiolase) (Mitochondrial 3-oxoacyl-CoA thiolase) Mus musculus (Mouse) acetyl-CoA metabolic process [GO:0006084]; cellular response to hypoxia [GO:0071456]; fatty acid beta-oxidation [GO:0006635]; negative regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902109]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029] GO:0003985; GO:0003986; GO:0003988; GO:0005739; GO:0005743; GO:0005759; GO:0006084; GO:0006635; GO:0016290; GO:0047617; GO:0071456; GO:0102991; GO:1901029; GO:1902109 12332 XM_044318829.1 316 0 0 32 46 Q5R9T9 1.67e-47 Guanylate-binding protein 6 (EC 3.6.5.-) (GTP-binding protein 6) (GBP-6) (Guanine nucleotide-binding protein 6) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cellular response to type II interferon [GO:0071346]; defense response to bacterium [GO:0042742]; immune response [GO:0006955] GO:0003924; GO:0005525; GO:0006955; GO:0031410; GO:0042742; GO:0071346 12333 XM_029331230.2 0 0 7 3 0 NA NA NA NA NA NA 12334 XM_044327389.1 1252 779 739 1154 1225 P0CB49 5.95e-87 YLP motif-containing protein 1 (Nuclear protein ZAP3) Rattus norvegicus (Rat) DNA-templated transcription [GO:0006351]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of telomere maintenance [GO:0032204] GO:0000122; GO:0001227; GO:0005634; GO:0006351; GO:0016607; GO:0032204 12335 XM_044307786.1 1160 319 612 704 503 P47990 0 Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase) (XOR)] Gallus gallus (Chicken) urate biosynthetic process [GO:0034418]; xanthine catabolic process [GO:0009115] GO:0004854; GO:0004855; GO:0005506; GO:0005615; GO:0005777; GO:0005829; GO:0009115; GO:0016491; GO:0030151; GO:0034418; GO:0043546; GO:0050660; GO:0051537; GO:0070674; GO:0071949 12336 XR_006395692.1 0 4 0 97 9 NA NA NA NA NA NA 12337 XM_029328604.2 599 735 1 647 37 Q8R3F5 1.76e-64 Malonyl-CoA-acyl carrier protein transacylase, mitochondrial (MCT) (EC 2.3.1.39) (Mitochondrial malonyltransferase) ([Acyl-carrier-protein] malonyltransferase) Mus musculus (Mouse) fatty acid biosynthetic process [GO:0006633] GO:0004312; GO:0004314; GO:0005739; GO:0006633 12338 XM_029323641.2 1645 1625 1036 1300 749 Q5BJT4 1.63e-34 Thioredoxin domain-containing protein 15 Rattus norvegicus (Rat) cilium assembly [GO:0060271]; positive regulation of smoothened signaling pathway [GO:0045880] GO:0005929; GO:0045880; GO:0060170; GO:0060271 12339 XM_029332411.2 91 0 0 0 12 Q8CG07 3.82e-137 ATPase WRNIP1 (EC 3.6.1.-) (Werner helicase-interacting protein 1) Rattus norvegicus (Rat) DNA synthesis involved in DNA repair [GO:0000731]; DNA-templated DNA replication [GO:0006261]; innate immune response [GO:0045087]; regulation of DNA-templated DNA replication initiation [GO:0030174] GO:0000731; GO:0000781; GO:0003677; GO:0005524; GO:0005634; GO:0006261; GO:0008047; GO:0016887; GO:0017116; GO:0030174; GO:0042802; GO:0045087; GO:0046872; GO:0048471 12340 XM_044323448.1 131 83 104 111 81 A6QLE5 1.38e-36 NACHT, LRR and PYD domains-containing protein 3 (EC 3.6.4.-) Bos taurus (Bovine) detection of biotic stimulus [GO:0009595]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; NLRP3 inflammasome complex assembly [GO:0044546]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type 2 immune response [GO:0002830]; protein homooligomerization [GO:0051260]; regulation of inflammatory response [GO:0050727] GO:0002674; GO:0002830; GO:0005524; GO:0005576; GO:0005634; GO:0005737; GO:0005783; GO:0006954; GO:0009595; GO:0016020; GO:0016887; GO:0031021; GO:0032731; GO:0032753; GO:0035591; GO:0043280; GO:0043531; GO:0043565; GO:0044546; GO:0045087; GO:0045630; GO:0045944; GO:0050727; GO:0050729; GO:0051260; GO:0070273; GO:0072559; GO:0140297; GO:0140299; GO:1901223; GO:1901981; GO:2000553 12341 XM_029324915.2 0 0 28 6 0 NA NA NA NA NA NA 12342 XM_044323002.1 0 0 13 4 93 P10090 1.02e-162 Protein white (EC 7.6.2.-) (EC 7.6.2.6) (ATP-binding cassette transporter sub-family G member white) (Broad substrate specificity ATP-binding cassette transporter white) Drosophila melanogaster (Fruit fly) aminergic neurotransmitter loading into synaptic vesicle [GO:0015842]; biogenic amine biosynthetic process [GO:0042401]; cGMP transport [GO:0070731]; compound eye pigmentation [GO:0048072]; eye pigment metabolic process [GO:0042441]; eye pigment precursor transport [GO:0006856]; gravitaxis [GO:0042332]; guanine transport [GO:0015854]; histamine uptake [GO:0051615]; male courtship behavior [GO:0008049]; memory [GO:0007613]; ommochrome biosynthetic process [GO:0006727]; riboflavin transport [GO:0032218]; transmembrane transport [GO:0055085]; tryptophan transport [GO:0015827]; xanthine transport [GO:0042906] GO:0005275; GO:0005524; GO:0005886; GO:0006727; GO:0006856; GO:0007613; GO:0008049; GO:0008558; GO:0015196; GO:0015208; GO:0015827; GO:0015842; GO:0015854; GO:0016020; GO:0016887; GO:0022857; GO:0030659; GO:0031409; GO:0031410; GO:0032217; GO:0032218; GO:0042332; GO:0042401; GO:0042441; GO:0042626; GO:0042906; GO:0042907; GO:0048072; GO:0048770; GO:0051615; GO:0055085; GO:0070731; GO:0090741; GO:0098793; GO:1905948 12343 XR_006396634.1 0 6 0 0 0 NA NA NA NA NA NA 12344 XM_044316940.1 246 210 210 211 179 Q6NUD0 7.45e-57 Methylosome protein 50 (MEP-50) (WD repeat-containing protein 77) Xenopus laevis (African clawed frog) NA GO:0005829; GO:0034709; GO:0035097 12345 XM_044313873.1 0 0 0 79 50 Q9DBE9 2.27e-132 pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3 (EC 2.1.1.-) (Protein ftsJ homolog 3) (Putative rRNA methyltransferase 3) Mus musculus (Mouse) enzyme-directed rRNA 2'-O-methylation [GO:0000453]; maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000466]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; RNA methylation [GO:0001510]; rRNA methylation [GO:0031167] GO:0000453; GO:0000463; GO:0000466; GO:0001510; GO:0005654; GO:0005694; GO:0005730; GO:0008173; GO:0008650; GO:0016435; GO:0030687; GO:0030688; GO:0031167; GO:0062105 12346 XM_044313873.1 0 0 0 79 50 Q9DBE9 1.1e-41 pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3 (EC 2.1.1.-) (Protein ftsJ homolog 3) (Putative rRNA methyltransferase 3) Mus musculus (Mouse) enzyme-directed rRNA 2'-O-methylation [GO:0000453]; maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000466]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; RNA methylation [GO:0001510]; rRNA methylation [GO:0031167] GO:0000453; GO:0000463; GO:0000466; GO:0001510; GO:0005654; GO:0005694; GO:0005730; GO:0008173; GO:0008650; GO:0016435; GO:0030687; GO:0030688; GO:0031167; GO:0062105 12347 XM_029334368.2 384 469 172 250 286 NA NA NA NA NA NA 12348 XR_003827318.2 54 26 48 60 23 NA NA NA NA NA NA 12349 XM_044323349.1 14 0 0 0 0 Q9H9B1 1.08e-148 Histone-lysine N-methyltransferase EHMT1 (EC 2.1.1.-) (EC 2.1.1.367) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a-like protein 1) (GLP) (GLP1) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Lysine N-methyltransferase 1D) Homo sapiens (Human) chromatin organization [GO:0006325]; DNA methylation [GO:0006306]; facultative heterochromatin formation [GO:0140718]; histone H3-K9 methylation [GO:0051567]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-lysine dimethylation [GO:0018027]; peptidyl-lysine monomethylation [GO:0018026]; positive regulation of cold-induced thermogenesis [GO:0120162]; regulation of embryonic development [GO:0045995]; regulation of histone H3-K9 methylation [GO:0051570] GO:0000122; GO:0000785; GO:0001222; GO:0002039; GO:0005634; GO:0005654; GO:0006306; GO:0006325; GO:0008168; GO:0008270; GO:0016279; GO:0016604; GO:0018024; GO:0018026; GO:0018027; GO:0045892; GO:0045995; GO:0046974; GO:0046976; GO:0051567; GO:0051570; GO:0070742; GO:0120162; GO:0140718; GO:0140947 12350 XM_029338255.2 648 0 0 0 267 O15014 2.77e-22 Zinc finger protein 609 Homo sapiens (Human) muscle organ development [GO:0007517]; positive regulation of neuron migration [GO:2001224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of myoblast proliferation [GO:2000291]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0005634; GO:0005654; GO:0006357; GO:0007517; GO:0045944; GO:0046872; GO:1990841; GO:2000291; GO:2001224 12351 XM_029335168.2 105 69 61 88 109 NA NA NA NA NA NA 12352 XM_044307889.1 0 0 0 0 12 Q09575 7.35e-32 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 12353 XM_044307889.1 0 0 0 0 12 Q09575 7.35e-32 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 12354 XM_029339352.2 1956 1293 1147 2180 1671 Q14643 0 Inositol 1,4,5-trisphosphate receptor type 1 (IP3 receptor isoform 1) (IP3R 1) (InsP3R1) (Type 1 inositol 1,4,5-trisphosphate receptor) (Type 1 InsP3 receptor) Homo sapiens (Human) calcium ion transport [GO:0006816]; cell morphogenesis [GO:0000902]; endoplasmic reticulum calcium ion homeostasis [GO:0032469]; epithelial fluid transport [GO:0042045]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; ion channel modulating, G protein-coupled receptor signaling pathway [GO:0099105]; ligand-gated ion channel signaling pathway [GO:1990806]; negative regulation of calcium-mediated signaling [GO:0050849]; phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway [GO:0007207]; positive regulation of insulin secretion [GO:0032024]; post-embryonic development [GO:0009791]; regulation of autophagy [GO:0010506]; release of sequestered calcium ion into cytosol [GO:0051209]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; voluntary musculoskeletal movement [GO:0050882] GO:0000902; GO:0001666; GO:0005220; GO:0005509; GO:0005637; GO:0005730; GO:0005783; GO:0005789; GO:0005886; GO:0005955; GO:0006816; GO:0007165; GO:0007207; GO:0009791; GO:0010506; GO:0014069; GO:0015085; GO:0015278; GO:0016020; GO:0016529; GO:0019855; GO:0019904; GO:0030658; GO:0030659; GO:0030667; GO:0031088; GO:0031094; GO:0031095; GO:0032024; GO:0032469; GO:0035091; GO:0042045; GO:0048471; GO:0050849; GO:0050882; GO:0051209; GO:0070059; GO:0070679; GO:0098685; GO:0098695; GO:0099103; GO:0099105; GO:0099107; GO:1990806 12355 XM_029323997.2 1605 970 958 1050 1610 Q8N584 1.23e-139 Tetratricopeptide repeat protein 39C (TPR repeat protein 39C) Homo sapiens (Human) cilium assembly [GO:0060271]; otolith morphogenesis [GO:0032474] GO:0032474; GO:0060271 12356 XM_044320331.1 816 442 303 581 393 NA NA NA NA NA NA 12357 XM_029323658.2 0 0 12 17 37 Q2KIA4 1.14e-108 Stearoyl-CoA desaturase 5 (EC 1.14.19.1) (Acyl-CoA-desaturase 4) (Stearoyl-CoA 9-desaturase) Bos taurus (Bovine) monounsaturated fatty acid biosynthetic process [GO:1903966]; unsaturated fatty acid biosynthetic process [GO:0006636] GO:0004768; GO:0005506; GO:0005789; GO:0006636; GO:0016491; GO:1903966 12358 XM_044326372.1 73 18 126 244 144 NA NA NA NA NA NA 12359 XM_044325636.1 168 23 191 13 275 P70490 1.08e-21 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 12360 XM_044313534.1 38 47 2 19 8 NA NA NA NA NA NA 12361 XM_029358267.2 494 565 334 855 485 P58308 7.14e-22 Orexin receptor type 2 (Ox-2-R) (Ox2-R) (Ox2R) (Hypocretin receptor type 2) Mus musculus (Mouse) circadian sleep/wake cycle process [GO:0022410]; feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; locomotion [GO:0040011]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; regulation of circadian sleep/wake cycle, wakefulness [GO:0010840]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0004930; GO:0005886; GO:0007186; GO:0007200; GO:0007218; GO:0007631; GO:0010840; GO:0016499; GO:0017046; GO:0022410; GO:0040011; GO:0051480 12362 XR_006396223.1 3077 792 403 1513 851 NA NA NA NA NA NA 12363 XR_006392827.1 0 0 15 0 13 NA NA NA NA NA NA 12364 XM_044326513.1 0 0 29 0 11 F1QZ15 1.1e-39 EKC/KEOPS complex subunit TPRKB (PRPK-binding protein) (TP53RK-binding protein) Danio rerio (Zebrafish) (Brachydanio rerio) tRNA threonylcarbamoyladenosine modification [GO:0002949] GO:0000408; GO:0002949; GO:0005634; GO:0005737; GO:0005829 12365 XM_029338357.2 1447 727 804 1164 1511 Q9NQG7 5.55e-30 BLOC-3 complex member HPS4 (Hermansky-Pudlak syndrome 4 protein) (Light-ear protein homolog) Homo sapiens (Human) blood coagulation [GO:0007596]; hemostasis [GO:0007599]; intracellular transport [GO:0046907]; lysosome organization [GO:0007040]; melanocyte differentiation [GO:0030318]; melanosome assembly [GO:1903232]; platelet dense granule organization [GO:0060155]; positive regulation of eye pigmentation [GO:0048075]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein stabilization [GO:0050821]; protein targeting [GO:0006605]; vesicle-mediated transport [GO:0016192] GO:0005085; GO:0005737; GO:0005764; GO:0005765; GO:0005829; GO:0006605; GO:0007040; GO:0007596; GO:0007599; GO:0016020; GO:0016192; GO:0030318; GO:0031085; GO:0031267; GO:0031410; GO:0042470; GO:0042803; GO:0042827; GO:0046907; GO:0046983; GO:0048075; GO:0050821; GO:0060155; GO:1903232; GO:1903955 12366 XR_003823948.2 35 1 20 74 56 NA NA NA NA NA NA 12367 XM_029331362.2 573 364 342 393 615 A3KQ55 4.71e-79 7SK snRNA methylphosphate capping enzyme (MePCE) (EC 2.1.1.-) (Bicoid-interacting protein 3 homolog) (Bin3 homolog) (zBCDIN3) Danio rerio (Zebrafish) (Brachydanio rerio) positive regulation of protein localization to Cajal body [GO:1904871]; positive regulation of snRNA transcription by RNA polymerase II [GO:1905382]; RNA methylation [GO:0001510]; snRNA metabolic process [GO:0016073]; snRNA modification [GO:0040031] GO:0001510; GO:0005634; GO:0008171; GO:0008173; GO:0008757; GO:0016073; GO:0017069; GO:0040031; GO:1904871; GO:1905382; GO:1990276; GO:1990904 12368 XM_044316999.1 19 5 1 0 33 O57382 5.82e-67 Tolloid-like protein 2 (EC 3.4.24.-) (Metalloprotease xolloid) (Xenopus tolloid) Xenopus laevis (African clawed frog) cell differentiation [GO:0030154]; proteolysis [GO:0006508] GO:0004222; GO:0005509; GO:0005576; GO:0006508; GO:0008270; GO:0030154 12369 XM_044316999.1 19 5 1 0 33 O57382 2.4e-64 Tolloid-like protein 2 (EC 3.4.24.-) (Metalloprotease xolloid) (Xenopus tolloid) Xenopus laevis (African clawed frog) cell differentiation [GO:0030154]; proteolysis [GO:0006508] GO:0004222; GO:0005509; GO:0005576; GO:0006508; GO:0008270; GO:0030154 12370 XM_044316999.1 19 5 1 0 33 O57382 4.57e-33 Tolloid-like protein 2 (EC 3.4.24.-) (Metalloprotease xolloid) (Xenopus tolloid) Xenopus laevis (African clawed frog) cell differentiation [GO:0030154]; proteolysis [GO:0006508] GO:0004222; GO:0005509; GO:0005576; GO:0006508; GO:0008270; GO:0030154 12371 XM_044312958.1 40 15 12 8 12 Q96P20 1.72e-50 NACHT, LRR and PYD domains-containing protein 3 (EC 3.6.4.-) (Angiotensin/vasopressin receptor AII/AVP-like) (Caterpiller protein 1.1) (CLR1.1) (Cold-induced autoinflammatory syndrome 1 protein) (Cryopyrin) (PYRIN-containing APAF1-like protein 1) Homo sapiens (Human) apoptotic process [GO:0006915]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to virus [GO:0098586]; defense response [GO:0006952]; detection of biotic stimulus [GO:0009595]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; NLRP3 inflammasome complex assembly [GO:0044546]; osmosensory signaling pathway [GO:0007231]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type 2 immune response [GO:0002830]; protein homooligomerization [GO:0051260]; pyroptosis [GO:0070269]; regulation of inflammatory response [GO:0050727]; signal transduction [GO:0007165] GO:0000139; GO:0002221; GO:0002674; GO:0002830; GO:0005524; GO:0005576; GO:0005634; GO:0005737; GO:0005739; GO:0005783; GO:0005815; GO:0005829; GO:0006915; GO:0006952; GO:0006954; GO:0007165; GO:0007231; GO:0009595; GO:0016020; GO:0016887; GO:0031021; GO:0032088; GO:0032691; GO:0032731; GO:0032753; GO:0035591; GO:0042802; GO:0042834; GO:0043280; GO:0043531; GO:0043565; GO:0044546; GO:0045087; GO:0045630; GO:0045944; GO:0050727; GO:0050728; GO:0050729; GO:0051092; GO:0051260; GO:0070269; GO:0070273; GO:0071222; GO:0072559; GO:0098586; GO:0140297; GO:0140299; GO:1901223; GO:1901981; GO:2000553 12372 XM_044315387.1 69 63 34 69 47 NA NA NA NA NA NA 12373 XM_029332037.2 19 8 48 6 24 P50222 1.39e-26 Homeobox protein MOX-2 (Growth arrest-specific homeobox) (Mesenchyme homeobox 2) Homo sapiens (Human) angiogenesis [GO:0001525]; limb development [GO:0060173]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; roof of mouth development [GO:0060021]; skeletal muscle tissue development [GO:0007519]; somite development [GO:0061053]; somite specification [GO:0001757] GO:0000785; GO:0000978; GO:0000981; GO:0001228; GO:0001525; GO:0001757; GO:0003700; GO:0005634; GO:0005737; GO:0006357; GO:0007519; GO:0016607; GO:0043565; GO:0045944; GO:0060021; GO:0060173; GO:0061053; GO:0090051; GO:1990837 12374 XR_006391532.1 328 303 254 216 512 Q7RTR2 1.58e-54 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12375 XR_006391532.1 328 303 254 216 512 Q7RTR2 7.44e-54 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12376 XR_006391532.1 328 303 254 216 512 Q7RTR2 5.3e-48 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12377 XR_006391532.1 328 303 254 216 512 Q7RTR2 2.79e-31 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12378 XR_006391532.1 328 303 254 216 512 Q7RTR2 2.53e-27 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12379 XM_044311332.1 4 1 0 2 1277 B0S5N4 0 Plexin A3 Danio rerio (Zebrafish) (Brachydanio rerio) axon extension [GO:0048675]; branching morphogenesis of a nerve [GO:0048755]; embryonic skeletal joint morphogenesis [GO:0060272]; motor neuron axon guidance [GO:0008045]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of collateral sprouting in absence of injury [GO:0048696]; regulation of GTPase activity [GO:0043087]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287] GO:0002116; GO:0005886; GO:0007162; GO:0008045; GO:0008360; GO:0016020; GO:0017154; GO:0030334; GO:0042802; GO:0043087; GO:0048675; GO:0048696; GO:0048755; GO:0050772; GO:0060272; GO:1902287 12380 XM_044322537.1 240 60 88 39 342 NA NA NA NA NA NA 12381 XR_006393717.1 1344 1203 858 1160 1120 Q8CFE4 5.7e-159 SCY1-like protein 2 (Coated vesicle-associated kinase of 104 kDa) Mus musculus (Mouse) brain development [GO:0007420]; endosome to lysosome transport [GO:0008333]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; positive regulation of clathrin-dependent endocytosis [GO:2000370]; positive regulation of receptor internalization [GO:0002092]; protein phosphorylation [GO:0006468]; pyramidal neuron development [GO:0021860]; receptor internalization involved in canonical Wnt signaling pathway [GO:2000286] GO:0002092; GO:0004672; GO:0005102; GO:0005524; GO:0005794; GO:0006468; GO:0007420; GO:0008333; GO:0010008; GO:0021860; GO:0030136; GO:0090090; GO:2000286; GO:2000370 12382 XR_006393717.1 1344 1203 858 1160 1120 Q8CFE4 5.7e-159 SCY1-like protein 2 (Coated vesicle-associated kinase of 104 kDa) Mus musculus (Mouse) brain development [GO:0007420]; endosome to lysosome transport [GO:0008333]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; positive regulation of clathrin-dependent endocytosis [GO:2000370]; positive regulation of receptor internalization [GO:0002092]; protein phosphorylation [GO:0006468]; pyramidal neuron development [GO:0021860]; receptor internalization involved in canonical Wnt signaling pathway [GO:2000286] GO:0002092; GO:0004672; GO:0005102; GO:0005524; GO:0005794; GO:0006468; GO:0007420; GO:0008333; GO:0010008; GO:0021860; GO:0030136; GO:0090090; GO:2000286; GO:2000370 12383 XR_006393717.1 1344 1203 858 1160 1120 Q8CFE4 5.7e-159 SCY1-like protein 2 (Coated vesicle-associated kinase of 104 kDa) Mus musculus (Mouse) brain development [GO:0007420]; endosome to lysosome transport [GO:0008333]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; positive regulation of clathrin-dependent endocytosis [GO:2000370]; positive regulation of receptor internalization [GO:0002092]; protein phosphorylation [GO:0006468]; pyramidal neuron development [GO:0021860]; receptor internalization involved in canonical Wnt signaling pathway [GO:2000286] GO:0002092; GO:0004672; GO:0005102; GO:0005524; GO:0005794; GO:0006468; GO:0007420; GO:0008333; GO:0010008; GO:0021860; GO:0030136; GO:0090090; GO:2000286; GO:2000370 12384 XM_044313473.1 0 9 0 8 35 NA NA NA NA NA NA 12385 XM_044324386.1 180 96 122 58 42 NA NA NA NA NA NA 12386 XM_029325725.2 342 317 385 374 736 O22943 2.36e-89 Probable glycosyltransferase STELLO1 (EC 2.4.-.-) Arabidopsis thaliana (Mouse-ear cress) plant-type cell wall cellulose biosynthetic process [GO:0052324]; regulation of plant-type cell wall cellulose biosynthetic process [GO:2001009] GO:0000139; GO:0005768; GO:0005794; GO:0005802; GO:0016757; GO:0042802; GO:0052324; GO:2001009 12387 XR_003828335.2 45 81 347 49 36 NA NA NA NA NA NA 12388 XM_029353951.2 0 0 0 32 143 B3EWY8 0 Skeletal aspartic acid-rich protein 2 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 12389 XM_029340610.2 135 89 106 117 122 F1R332 2.26e-21 Galanin receptor 2a Danio rerio (Zebrafish) (Brachydanio rerio) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; neuropeptide signaling pathway [GO:0007218] GO:0004966; GO:0005886; GO:0007188; GO:0007218; GO:0008528 12390 XM_044325484.1 184 155 264 322 186 Q96D46 0 60S ribosomal export protein NMD3 (hNMD3) Homo sapiens (Human) positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to nucleolus [GO:1904751]; positive regulation of RNA biosynthetic process [GO:1902680]; protein transport [GO:0015031]; ribosomal large subunit export from nucleus [GO:0000055] GO:0000055; GO:0003723; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0015031; GO:0016020; GO:0030674; GO:0032092; GO:0043023; GO:1902680; GO:1904751 12391 XM_044321858.1 15 0 24 8 69 B3EWZ3 1.24e-54 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 12392 XM_044321858.1 15 0 24 8 69 B3EWZ3 5.62e-48 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 12393 XM_044321858.1 15 0 24 8 69 B3EWZ3 4.14e-47 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 12394 XM_044321858.1 15 0 24 8 69 B3EWZ3 2.6e-39 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 12395 XM_044321858.1 15 0 24 8 69 B3EWZ3 1.03e-27 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 12396 XM_029355702.2 2714 2410 1780 2939 2761 Q3T0K2 0 T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma) Bos taurus (Bovine) binding of sperm to zona pellucida [GO:0007339]; chaperone-mediated protein folding [GO:0061077]; pore complex assembly [GO:0046931]; positive regulation of establishment of protein localization to telomere [GO:1904851]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein folding [GO:0006457]; protein stabilization [GO:0050821]; toxin transport [GO:1901998] GO:0002199; GO:0005524; GO:0005832; GO:0005874; GO:0006457; GO:0007339; GO:0016887; GO:0032212; GO:0044297; GO:0046931; GO:0050821; GO:0051082; GO:0061077; GO:0140662; GO:1901998; GO:1904851 12397 XM_029326409.2 654 283 195 753 527 Q9P4X3 6.29e-170 Probable U3 small nucleolar RNA-associated protein 7 (U3 snoRNA-associated protein 7) (U three protein 7) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462] GO:0000462; GO:0005730; GO:0005732; GO:0030515; GO:0032040 12398 XM_029351081.2 59 0 46 7 148 NA NA NA NA NA NA 12399 XM_029333284.2 321 147 127 302 189 P24463 4.06e-54 Cytochrome P450 3A12 (EC 1.14.14.1) (CYPIIIA12) (Cytochrome P450-PBD-1) Canis lupus familiaris (Dog) (Canis familiaris) hormone metabolic process [GO:0042445]; organic hydroxy compound metabolic process [GO:1901615]; oxidative demethylation [GO:0070989]; progesterone metabolic process [GO:0042448]; steroid metabolic process [GO:0008202] GO:0004497; GO:0005506; GO:0005789; GO:0008202; GO:0008395; GO:0020037; GO:0042445; GO:0042448; GO:0050649; GO:0070330; GO:0070989; GO:1901615 12400 XR_006395637.1 1434 8 321 2071 603 NA NA NA NA NA NA 12401 XM_044322229.1 158 139 108 81 153 NA NA NA NA NA NA 12402 XM_044316781.1 941 314 314 233 376 P33731 5.44e-158 Signal recognition particle subunit SRP72 (SRP72) (Signal recognition particle 72 kDa protein) Canis lupus familiaris (Dog) (Canis familiaris) SRP-dependent cotranslational protein targeting to membrane [GO:0006614] GO:0005047; GO:0005783; GO:0005786; GO:0005829; GO:0006614; GO:0008312; GO:0030911; GO:0043022 12403 XM_044318767.1 19 87 85 54 36 NA NA NA NA NA NA 12404 XM_044311706.1 3 9 0 10 5 NA NA NA NA NA NA 12405 XM_029338088.2 260 184 195 153 202 Q9W770 9.58e-70 Spondin-1 (F-spondin) Gallus gallus (Chicken) cell adhesion [GO:0007155] GO:0005576; GO:0007155; GO:0031012; GO:0046872 12406 XM_029338088.2 260 184 195 153 202 Q9W770 7.97e-21 Spondin-1 (F-spondin) Gallus gallus (Chicken) cell adhesion [GO:0007155] GO:0005576; GO:0007155; GO:0031012; GO:0046872 12407 XM_029357745.2 378 311 200 325 380 Q5XI68 2.55e-55 Protein Dr1 (Down-regulator of transcription 1) (Negative cofactor 2-beta) (NC2-beta) (TATA-binding protein-associated phosphoprotein) Rattus norvegicus (Rat) chromatin remodeling [GO:0006338]; histone H3 acetylation [GO:0043966]; histone H3-K14 acetylation [GO:0044154]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell cycle [GO:0051726]; regulation of cell division [GO:0051302]; regulation of DNA-templated transcription [GO:0006355]; regulation of embryonic development [GO:0045995]; regulation of histone deacetylation [GO:0031063]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tubulin deacetylation [GO:0090043]; RNA polymerase II preinitiation complex assembly [GO:0051123] GO:0000122; GO:0001046; GO:0005634; GO:0006338; GO:0006355; GO:0006357; GO:0016251; GO:0017025; GO:0017054; GO:0031063; GO:0043966; GO:0044154; GO:0045944; GO:0045995; GO:0046982; GO:0051123; GO:0051302; GO:0051726; GO:0090043; GO:0090575; GO:0140672 12408 XR_006396063.1 1458 624 519 677 692 Q11126 2.63e-34 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3 (EC 2.4.1.65) (4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase) (EC 2.4.1.152) (Alpha-3-fucosyltransferase FUT3) (EC 2.4.1.-) (Blood group Lewis alpha-4-fucosyltransferase) (Lewis FT) (FUTB) (Fucosyltransferase 3) (Fucosyltransferase III) (FucT-III) Bos taurus (Bovine) fucosylation [GO:0036065]; lipid metabolic process [GO:0006629]; oligosaccharide metabolic process [GO:0009311]; positive regulation of cell-cell adhesion [GO:0022409]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127] GO:0006487; GO:0006493; GO:0006629; GO:0009311; GO:0017060; GO:0017083; GO:0022409; GO:0030334; GO:0032580; GO:0036065; GO:0042127; GO:0046920 12409 XR_006396063.1 1458 624 519 677 692 Q11126 2.63e-34 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3 (EC 2.4.1.65) (4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase) (EC 2.4.1.152) (Alpha-3-fucosyltransferase FUT3) (EC 2.4.1.-) (Blood group Lewis alpha-4-fucosyltransferase) (Lewis FT) (FUTB) (Fucosyltransferase 3) (Fucosyltransferase III) (FucT-III) Bos taurus (Bovine) fucosylation [GO:0036065]; lipid metabolic process [GO:0006629]; oligosaccharide metabolic process [GO:0009311]; positive regulation of cell-cell adhesion [GO:0022409]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127] GO:0006487; GO:0006493; GO:0006629; GO:0009311; GO:0017060; GO:0017083; GO:0022409; GO:0030334; GO:0032580; GO:0036065; GO:0042127; GO:0046920 12410 XM_044320455.1 3647 1661 1840 2779 2660 Q5RJF7 3.44e-103 Voltage-dependent calcium channel subunit alpha-2/delta-4 (Voltage-gated calcium channel subunit alpha-2/delta-4) [Cleaved into: Voltage-dependent calcium channel subunit alpha-2-4; Voltage-dependent calcium channel subunit delta-4] Mus musculus (Mouse) calcium ion transmembrane transport [GO:0070588]; detection of light stimulus involved in visual perception [GO:0050908]; regulation of ion transmembrane transport [GO:0034765] GO:0005245; GO:0005891; GO:0034765; GO:0046872; GO:0050908; GO:0070588 12411 XM_029323666.2 323 124 77 70 85 Q92038 2.99e-117 Acyl-CoA desaturase (EC 1.14.19.1) (Delta(9)-desaturase) (Delta-9 desaturase) (Fatty acid desaturase) (Stearoyl-CoA desaturase) Cyprinus carpio (Common carp) unsaturated fatty acid biosynthetic process [GO:0006636] GO:0004768; GO:0005506; GO:0005789; GO:0006636; GO:0016020; GO:0016491 12412 XM_029352806.2 1209 1105 446 1048 655 NA NA NA NA NA NA 12413 XM_044319387.1 24 29 5 16 23 NA NA NA NA NA NA 12414 XM_029337723.2 462 1007 283 552 993 NA NA NA NA NA NA 12415 XM_044327044.1 8 0 56 23 107 A4IGL7 7.85e-87 Peroxidasin (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0005576; GO:0005604; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0031012; GO:0042744; GO:0046872; GO:0051260; GO:0070207; GO:0070831; GO:0071711; GO:0140825 12416 XM_044321272.1 144 44 47 106 89 Q99M87 5.99e-122 DnaJ homolog subfamily A member 3, mitochondrial (DnaJ protein Tid-1) (mTid-1) (Tumorous imaginal discs protein Tid56 homolog) Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation-induced cell death of T cells [GO:0006924]; apoptotic process [GO:0006915]; cellular senescence [GO:0090398]; mitochondrial DNA replication [GO:0006264]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type II interferon-mediated signaling pathway [GO:0060336]; neuromuscular junction development [GO:0007528]; positive regulation of apoptotic process [GO:0043065]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of T cell proliferation [GO:0042102]; protein folding [GO:0006457]; protein stabilization [GO:0050821]; response to heat [GO:0009408]; response to type II interferon [GO:0034341]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; small GTPase mediated signal transduction [GO:0007264]; T cell differentiation in thymus [GO:0033077] GO:0000122; GO:0005133; GO:0005524; GO:0005634; GO:0005737; GO:0005739; GO:0005759; GO:0005829; GO:0005884; GO:0005886; GO:0006264; GO:0006457; GO:0006469; GO:0006915; GO:0006919; GO:0006924; GO:0007005; GO:0007264; GO:0007528; GO:0008285; GO:0009408; GO:0019897; GO:0019901; GO:0030544; GO:0030695; GO:0030971; GO:0031398; GO:0031594; GO:0032088; GO:0033077; GO:0034341; GO:0042102; GO:0042645; GO:0043065; GO:0043066; GO:0043069; GO:0043124; GO:0043154; GO:0043231; GO:0044877; GO:0045211; GO:0046872; GO:0050821; GO:0051059; GO:0051082; GO:0060336; GO:0061629; GO:0071340; GO:0090398; GO:0106137; GO:0140297 12417 XM_029330604.2 3 39 94 403 95 NA NA NA NA NA NA 12418 XM_029349687.2 0 0 1 0 13 P97363 4.89e-177 Serine palmitoyltransferase 2 (EC 2.3.1.50) (Long chain base biosynthesis protein 2) (LCB 2) (Long chain base biosynthesis protein 2a) (LCB2a) (Serine-palmitoyl-CoA transferase 2) (SPT 2) Mus musculus (Mouse) adipose tissue development [GO:0060612]; ceramide biosynthetic process [GO:0046513]; lipophagy [GO:0061724]; positive regulation of lipophagy [GO:1904504]; sphinganine biosynthetic process [GO:0046511]; sphingolipid biosynthetic process [GO:0030148]; sphingomyelin biosynthetic process [GO:0006686]; sphingosine biosynthetic process [GO:0046512] GO:0004758; GO:0005739; GO:0005789; GO:0006686; GO:0017059; GO:0030148; GO:0030170; GO:0046511; GO:0046512; GO:0046513; GO:0060612; GO:0061724; GO:1904504 12419 XR_003824643.2 187 168 91 181 70 NA NA NA NA NA NA 12420 XM_044310060.1 2 7 22 30 45 NA NA NA NA NA NA 12421 XM_029325275.2 508 426 299 451 514 NA NA NA NA NA NA 12422 XM_044315300.1 2896 1386 1196 2614 2199 Q9EQH2 0 Endoplasmic reticulum aminopeptidase 1 (EC 3.4.11.-) (ARTS-1) (Adipocyte-derived leucine aminopeptidase) (A-LAP) (Aminopeptidase PILS) (Puromycin-insensitive leucyl-specific aminopeptidase) (PILS-AP) (VEGF-induced aminopeptidase) Mus musculus (Mouse) adaptive immune response [GO:0002250]; membrane protein ectodomain proteolysis [GO:0006509]; peptide catabolic process [GO:0043171]; positive regulation of angiogenesis [GO:0045766]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; signal transduction [GO:0007165] GO:0002250; GO:0004175; GO:0004177; GO:0005138; GO:0005164; GO:0005576; GO:0005737; GO:0005788; GO:0005789; GO:0005886; GO:0006508; GO:0006509; GO:0007165; GO:0008217; GO:0008233; GO:0008235; GO:0008270; GO:0030163; GO:0042277; GO:0043171; GO:0043231; GO:0045766; GO:0070006 12423 XM_044315300.1 2896 1386 1196 2614 2199 Q9EQH2 7.93e-154 Endoplasmic reticulum aminopeptidase 1 (EC 3.4.11.-) (ARTS-1) (Adipocyte-derived leucine aminopeptidase) (A-LAP) (Aminopeptidase PILS) (Puromycin-insensitive leucyl-specific aminopeptidase) (PILS-AP) (VEGF-induced aminopeptidase) Mus musculus (Mouse) adaptive immune response [GO:0002250]; membrane protein ectodomain proteolysis [GO:0006509]; peptide catabolic process [GO:0043171]; positive regulation of angiogenesis [GO:0045766]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; signal transduction [GO:0007165] GO:0002250; GO:0004175; GO:0004177; GO:0005138; GO:0005164; GO:0005576; GO:0005737; GO:0005788; GO:0005789; GO:0005886; GO:0006508; GO:0006509; GO:0007165; GO:0008217; GO:0008233; GO:0008235; GO:0008270; GO:0030163; GO:0042277; GO:0043171; GO:0043231; GO:0045766; GO:0070006 12424 XM_029339994.2 1076 531 453 869 896 Q1LZF8 4.51e-25 Chloride channel CLIC-like protein 1 Bos taurus (Bovine) NA GO:0000139; GO:0005254; GO:0005783; GO:0005789; GO:0031965; GO:0034707; GO:0044233 12425 XM_029355581.2 533 673 16 566 161 Q5ZIJ9 9.26e-50 E3 ubiquitin-protein ligase MIB2 (EC 2.3.2.27) (Mind bomb homolog 2) (RING-type E3 ubiquitin transferase MIB2) Gallus gallus (Chicken) Notch signaling pathway [GO:0007219]; protein ubiquitination [GO:0016567] GO:0004842; GO:0005737; GO:0007219; GO:0008270; GO:0016567 12426 XM_044319936.1 197 394 207 693 280 Q68DA7 9.64e-70 Formin-1 (Limb deformity protein homolog) Homo sapiens (Human) actin nucleation [GO:0045010]; forelimb morphogenesis [GO:0035136]; gene expression [GO:0010467]; hindlimb morphogenesis [GO:0035137]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of actin nucleation [GO:0051127]; positive regulation of focal adhesion assembly [GO:0051894]; skeletal system morphogenesis [GO:0048705]; ureteric bud invasion [GO:0072092] GO:0003779; GO:0005634; GO:0005737; GO:0005789; GO:0005884; GO:0005886; GO:0005912; GO:0008017; GO:0010467; GO:0017124; GO:0030838; GO:0035136; GO:0035137; GO:0045010; GO:0048705; GO:0051127; GO:0051894; GO:0072092 12427 XM_044308424.1 600 189 517 1103 2333 Q54PI5 1.51e-39 Probable gluconokinase (EC 2.7.1.12) (Gluconate kinase) Dictyostelium discoideum (Social amoeba) D-gluconate catabolic process [GO:0046177]; phosphorylation [GO:0016310] GO:0005524; GO:0016310; GO:0046177; GO:0046316 12428 XM_044311120.1 38 694 20 86 36 NA NA NA NA NA NA 12429 XM_044324190.1 0 0 329 0 19 Q9UPU7 9.57e-51 TBC1 domain family member 2B Homo sapiens (Human) activation of GTPase activity [GO:0090630]; endocytosis [GO:0006897] GO:0005096; GO:0005769; GO:0005829; GO:0006897; GO:0090630 12430 XM_044318955.1 66 0 0 0 101 P39429 8.27e-25 TNF receptor-associated factor 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF2) (RING-type E3 ubiquitin transferase TRAF2) Mus musculus (Mouse) activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; cellular response to nitric oxide [GO:0071732]; interleukin-17-mediated signaling pathway [GO:0097400]; mRNA stabilization [GO:0048255]; negative regulation of apoptotic process [GO:0043066]; negative regulation of glial cell apoptotic process [GO:0034351]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein K63-linked ubiquitination [GO:0070534]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin production [GO:0002637]; regulation of JNK cascade [GO:0046328]; regulation of protein-containing complex assembly [GO:0043254]; signal transduction [GO:0007165]; signal transduction involved in regulation of gene expression [GO:0023019]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000151; GO:0002637; GO:0002726; GO:0002947; GO:0004842; GO:0005164; GO:0005174; GO:0005737; GO:0005829; GO:0005938; GO:0006915; GO:0007165; GO:0007250; GO:0008270; GO:0009898; GO:0012506; GO:0019899; GO:0019901; GO:0019903; GO:0023019; GO:0030163; GO:0030674; GO:0031435; GO:0031625; GO:0031996; GO:0032743; GO:0032991; GO:0033209; GO:0034351; GO:0035631; GO:0042802; GO:0042981; GO:0043066; GO:0043120; GO:0043122; GO:0043123; GO:0043254; GO:0043507; GO:0044877; GO:0045121; GO:0046328; GO:0046330; GO:0046625; GO:0048255; GO:0051091; GO:0051092; GO:0051865; GO:0065003; GO:0070534; GO:0071732; GO:0097057; GO:0097300; GO:0097400; GO:1903265; GO:1903721; GO:1990604; GO:2001238 12431 XM_044307870.1 180 155 52 112 114 NA NA NA NA NA NA 12432 XM_029336318.2 325 339 382 649 330 Q9NZV8 2.76e-98 Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2) Homo sapiens (Human) action potential [GO:0001508]; cellular response to hypoxia [GO:0071456]; chemical synaptic transmission [GO:0007268]; locomotor rhythm [GO:0045475]; neuronal action potential [GO:0019228]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233] GO:0001508; GO:0005249; GO:0005250; GO:0005886; GO:0007268; GO:0008076; GO:0014069; GO:0016020; GO:0019228; GO:0019233; GO:0032809; GO:0034765; GO:0043197; GO:0043204; GO:0044853; GO:0045211; GO:0045475; GO:0046872; GO:0051260; GO:0070161; GO:0071456; GO:0071805; GO:0098978; GO:0098982; GO:0099634; GO:1905030 12433 XR_006395092.1 23 0 0 181 16 NA NA NA NA NA NA 12434 XM_029344016.2 4290 4535 2842 5241 5177 P81117 1.88e-53 Nucleobindin-2 (DNA-binding protein NEFA) (Prepronesfatin) [Cleaved into: Nesfatin-1] Mus musculus (Mouse) cellular calcium ion homeostasis [GO:0006874]; insulin metabolic process [GO:1901142]; negative regulation of appetite [GO:0032099]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of glucagon secretion [GO:0070093]; negative regulation of insulin receptor signaling pathway [GO:0046627]; positive regulation of fatty acid oxidation [GO:0046321]; positive regulation of testosterone secretion [GO:2000845]; small GTPase mediated signal transduction [GO:0007264] GO:0001965; GO:0003677; GO:0005085; GO:0005164; GO:0005509; GO:0005615; GO:0005634; GO:0005640; GO:0005737; GO:0005783; GO:0005793; GO:0005794; GO:0005797; GO:0006874; GO:0007264; GO:0032099; GO:0043204; GO:0043951; GO:0045599; GO:0046321; GO:0046627; GO:0070093; GO:1901142; GO:2000845 12435 XR_006394288.1 0 0 6 24 0 NA NA NA NA NA NA 12436 XM_029348044.2 1151 856 737 1127 810 B2RW38 0 Cilia- and flagella-associated protein 58 Mus musculus (Mouse) cilium assembly [GO:0060271]; flagellated sperm motility [GO:0030317]; Notch signaling pathway [GO:0007219]; protein localization to motile cilium [GO:0120229]; sperm axoneme assembly [GO:0007288]; sperm flagellum assembly [GO:0120316]; sperm mitochondrial sheath assembly [GO:0120317] GO:0005737; GO:0005813; GO:0005856; GO:0007219; GO:0007288; GO:0030317; GO:0036126; GO:0060271; GO:0097225; GO:0120229; GO:0120316; GO:0120317 12437 XM_044310559.1 107 72 342 394 393 NA NA NA NA NA NA 12438 XM_029344769.2 493 401 352 562 591 Q28IV8 3.19e-65 Neuroguidin (EIF4E-binding protein) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) regulation of translation [GO:0006417] GO:0005634; GO:0005737; GO:0006417 12439 XM_029348363.2 94 29 0 67 18 Q99741 1.37e-133 Cell division control protein 6 homolog (CDC6-related protein) (Cdc18-related protein) (HsCdc18) (p62(cdc6)) (HsCDC6) Homo sapiens (Human) cell division [GO:0051301]; cellular response to angiotensin [GO:1904385]; cellular response to vasopressin [GO:1904117]; DNA replication checkpoint signaling [GO:0000076]; DNA replication initiation [GO:0006270]; mitotic cell cycle [GO:0000278]; mitotic DNA replication checkpoint signaling [GO:0033314]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; positive regulation of chromosome segregation [GO:0051984]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytokinesis [GO:0032467]; positive regulation of fibroblast proliferation [GO:0048146]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; traversing start control point of mitotic cell cycle [GO:0007089] GO:0000076; GO:0000079; GO:0000166; GO:0000278; GO:0000922; GO:0003688; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006270; GO:0007089; GO:0008156; GO:0008285; GO:0019900; GO:0030071; GO:0032467; GO:0033314; GO:0045171; GO:0045737; GO:0048146; GO:0051233; GO:0051301; GO:0051984; GO:0072686; GO:1904117; GO:1904385 12440 XM_044309577.1 0 8 3 17 0 NA NA NA NA NA NA 12441 XM_044319728.1 32 995 183 228 225 Q9VS29 3.18e-28 Cell adhesion molecule Dscam2 (Down syndrome cell adhesion molecule-like protein Dscam2) Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; dendrite self-avoidance [GO:0070593]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron projection morphogenesis [GO:0048812] GO:0005886; GO:0007156; GO:0007411; GO:0030424; GO:0042802; GO:0048812; GO:0070593; GO:0098632 12442 XM_044319728.1 32 995 183 228 225 Q9VS29 6.43e-21 Cell adhesion molecule Dscam2 (Down syndrome cell adhesion molecule-like protein Dscam2) Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; dendrite self-avoidance [GO:0070593]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron projection morphogenesis [GO:0048812] GO:0005886; GO:0007156; GO:0007411; GO:0030424; GO:0042802; GO:0048812; GO:0070593; GO:0098632 12443 XM_029353818.2 6542 4739 3138 7597 8274 NA NA NA NA NA NA 12444 XM_044320459.1 37 13 0 28 6 NA NA NA NA NA NA 12445 XR_006395867.1 8 4 1 0 1 NA NA NA NA NA NA 12446 XR_003824018.2 918 366 417 567 550 NA NA NA NA NA NA 12447 XM_044313005.1 0 0 8 0 12 NA NA NA NA NA NA 12448 XM_044310035.1 0 44 0 0 0 P70490 4.09e-52 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 12449 XM_044310035.1 0 44 0 0 0 P70490 4.54e-52 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 12450 XM_044310035.1 0 44 0 0 0 P70490 3.21e-51 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 12451 XM_044310035.1 0 44 0 0 0 P70490 3.47e-51 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 12452 XM_044310035.1 0 44 0 0 0 P70490 9.13e-51 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 12453 XM_044310035.1 0 44 0 0 0 P70490 1.06e-50 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 12454 XM_044310035.1 0 44 0 0 0 P70490 2.91e-50 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 12455 XM_044310035.1 0 44 0 0 0 P70490 5.76e-50 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 12456 XM_044310035.1 0 44 0 0 0 P70490 6.33e-50 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 12457 XM_044310035.1 0 44 0 0 0 P70490 9.99e-50 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 12458 XM_044310035.1 0 44 0 0 0 P70490 1.39e-49 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 12459 XM_044310035.1 0 44 0 0 0 P70490 1.89e-49 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 12460 XM_044310035.1 0 44 0 0 0 P70490 2.89e-49 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 12461 XM_044310035.1 0 44 0 0 0 P70490 3e-49 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 12462 XM_044310035.1 0 44 0 0 0 P70490 7.12e-49 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 12463 XM_044310035.1 0 44 0 0 0 P70490 7.98e-49 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 12464 XM_044310035.1 0 44 0 0 0 P70490 3.4e-48 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 12465 XM_029339087.2 568 353 470 1076 0 Q9CYL5 6.46e-39 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Mus musculus (Mouse) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070374 12466 XM_029339087.2 568 353 470 1076 0 Q9CYL5 5.18e-35 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Mus musculus (Mouse) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070374 12467 XR_006395513.1 45 11 0 2 9 NA NA NA NA NA NA 12468 XR_003825613.2 100 82 47 78 69 NA NA NA NA NA NA 12469 XM_044310499.1 8 18 10 11 2 NA NA NA NA NA NA 12470 XM_029357106.2 246 106 124 154 259 A0A2B4RNI3 1.12e-29 NA NA NA NA 12471 XM_029353823.2 443 649 203 848 254 NA NA NA NA NA NA 12472 XM_029341638.2 1525 969 699 1375 1170 Q8R2E9 8.24e-143 ERO1-like protein beta (ERO1-L-beta) (EC 1.8.4.-) (Endoplasmic reticulum oxidoreductase beta) (Endoplasmic reticulum oxidoreductin-1-like protein B) (Oxidoreductin-1-L-beta) Mus musculus (Mouse) cell redox homeostasis [GO:0045454]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; extracellular matrix organization [GO:0030198]; glucose homeostasis [GO:0042593]; insulin processing [GO:0030070]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; protein folding in endoplasmic reticulum [GO:0034975]; protein maturation by protein folding [GO:0022417] GO:0005788; GO:0005789; GO:0006888; GO:0015035; GO:0015036; GO:0016020; GO:0016972; GO:0018401; GO:0022417; GO:0030070; GO:0030198; GO:0034975; GO:0042593; GO:0045454; GO:0071949 12473 XM_044309274.1 57 0 55 6 146 NA NA NA NA NA NA 12474 XM_044318802.1 0 12 6 0 5 P04274 4.62e-25 Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor) Mesocricetus auratus (Golden hamster) activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; bone resorption [GO:0045453]; brown fat cell differentiation [GO:0050873]; cellular response to amyloid-beta [GO:1904646]; desensitization of G protein-coupled receptor signaling pathway by arrestin [GO:0002032]; diet induced thermogenesis [GO:0002024]; heat generation [GO:0031649]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of smooth muscle contraction [GO:0045986]; norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0002025]; positive regulation of AMPA receptor activity [GO:2000969]; positive regulation of autophagosome maturation [GO:1901098]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of lipophagy [GO:1904504]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mini excitatory postsynaptic potential [GO:0061885]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor-mediated endocytosis [GO:0006898]; regulation of sodium ion transport [GO:0002028]; response to cold [GO:0009409]; smooth muscle contraction [GO:0006939]; transcription by RNA polymerase II [GO:0006366] GO:0001540; GO:0002024; GO:0002025; GO:0002028; GO:0002032; GO:0004941; GO:0005634; GO:0005769; GO:0005794; GO:0006366; GO:0006898; GO:0006939; GO:0007189; GO:0007190; GO:0008179; GO:0009409; GO:0010739; GO:0015459; GO:0016324; GO:0030501; GO:0031649; GO:0040015; GO:0042803; GO:0043235; GO:0043410; GO:0044877; GO:0045453; GO:0045944; GO:0045986; GO:0050873; GO:0051380; GO:0061885; GO:0071902; GO:0098992; GO:0120162; GO:1901098; GO:1904504; GO:1904646; GO:2000969 12475 XM_044323798.1 0 0 6 0 17 NA NA NA NA NA NA 12476 XR_006392991.1 41 2 25 5 151 NA NA NA NA NA NA 12477 XM_029344771.2 10708 12322 8680 12079 16296 NA NA NA NA NA NA 12478 XR_006391840.1 7 0 4 16 3 NA NA NA NA NA NA 12479 XM_029325946.2 1906 1600 1582 1554 1770 O95147 1.3e-54 Dual specificity protein phosphatase 14 (EC 3.1.3.16) (EC 3.1.3.48) (MKP-1-like protein tyrosine phosphatase) (MKP-L) (Mitogen-activated protein kinase phosphatase 6) (MAP kinase phosphatase 6) (MKP-6) Homo sapiens (Human) protein dephosphorylation [GO:0006470] GO:0003723; GO:0004725; GO:0006470; GO:0017017; GO:0017018 12480 XM_029330541.2 0 0 19 158 52 Q96AY4 4.98e-81 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12481 XM_029330541.2 0 0 19 158 52 Q96AY4 7.3e-80 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12482 XM_029330541.2 0 0 19 158 52 Q96AY4 3.71e-77 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12483 XM_029330541.2 0 0 19 158 52 Q96AY4 1.54e-76 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12484 XM_029330541.2 0 0 19 158 52 Q96AY4 5.35e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12485 XR_006397710.1 175 47 183 63 488 NA NA NA NA NA NA 12486 XM_044310819.1 72 0 1 195 2 NA NA NA NA NA NA 12487 XM_029329615.2 183 166 102 257 97 Q05209 1.71e-74 Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (PTP-PEST) (Protein-tyrosine phosphatase G1) (PTPG1) Homo sapiens (Human) cellular response to epidermal growth factor stimulus [GO:0071364]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; tissue regeneration [GO:0042246] GO:0002102; GO:0004721; GO:0004725; GO:0004726; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005925; GO:0006470; GO:0017124; GO:0035335; GO:0042058; GO:0042246; GO:0042995; GO:0071364; GO:1901185; GO:2000587 12488 XM_029340551.2 158 423 86 185 128 Q59990 1.55e-28 Putative cytochrome P450 120 (EC 1.14.-.-) Synechocystis sp. (strain PCC 6803 / Kazusa) sterol metabolic process [GO:0016125] GO:0004497; GO:0005506; GO:0016125; GO:0016491; GO:0016705; GO:0020037 12489 XM_044307292.1 0 0 0 96 0 O54701 1.17e-149 Sodium/potassium/calcium exchanger 2 (Na(+)/K(+)/Ca(2+)-exchange protein 2) (Retinal cone Na-Ca+K exchanger) (Solute carrier family 24 member 2) Rattus norvegicus (Rat) calcium ion import [GO:0070509]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; cellular response to high light intensity [GO:0071486]; establishment of localization in cell [GO:0051649]; ion transmembrane transport [GO:0034220]; learning [GO:0007612]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; neuron cellular homeostasis [GO:0070050]; potassium ion transmembrane transport [GO:0071805]; protein-containing complex assembly [GO:0065003]; sodium ion transmembrane transport [GO:0035725] GO:0005262; GO:0005886; GO:0006816; GO:0006874; GO:0007612; GO:0007613; GO:0008273; GO:0015293; GO:0016020; GO:0034220; GO:0035725; GO:0051649; GO:0060291; GO:0060292; GO:0065003; GO:0070050; GO:0070509; GO:0070588; GO:0071486; GO:0071805; GO:0098703 12490 XM_029343625.2 0 6 0 19 9 NA NA NA NA NA NA 12491 XM_029353812.2 654 418 302 509 571 Q6PKC3 4.21e-62 Thioredoxin domain-containing protein 11 (EF-hand-binding protein 1) Homo sapiens (Human) NA GO:0005789 12492 XR_003825749.2 225 180 45 104 45 NA NA NA NA NA NA 12493 XR_006394468.1 42 34 22 27 10 NA NA NA NA NA NA 12494 XM_029337749.2 7 92 149 0 119 P13697 0 NADP-dependent malic enzyme (NADP-ME) (EC 1.1.1.40) (Malic enzyme 1) Rattus norvegicus (Rat) malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; NADP metabolic process [GO:0006739]; protein homotetramerization [GO:0051289]; pyruvate metabolic process [GO:0006090]; regulation of NADP metabolic process [GO:1902031]; response to hormone [GO:0009725] GO:0000287; GO:0004470; GO:0004471; GO:0004473; GO:0005737; GO:0005739; GO:0005829; GO:0006090; GO:0006108; GO:0006734; GO:0006739; GO:0008948; GO:0009725; GO:0030145; GO:0042802; GO:0050661; GO:0051287; GO:0051289; GO:1902031 12495 XM_044325492.1 44 15 20 49 47 P25291 2.02e-25 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 12496 XM_029341775.2 127 40 14 96 5 NA NA NA NA NA NA 12497 XM_044326313.1 22 11 8 52 11 P23511 6.45e-29 Nuclear transcription factor Y subunit alpha (CAAT box DNA-binding protein subunit A) (Nuclear transcription factor Y subunit A) (NF-YA) Homo sapiens (Human) histone H3-K4 trimethylation [GO:0080182]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of histone acetylation [GO:0035065]; regulation of transcription by RNA polymerase II [GO:0006357]; rhythmic process [GO:0048511]; transcription by RNA polymerase II [GO:0006366] GO:0000785; GO:0000978; GO:0000981; GO:0003677; GO:0003700; GO:0005634; GO:0005654; GO:0006355; GO:0006357; GO:0006366; GO:0016602; GO:0032993; GO:0035065; GO:0045893; GO:0045944; GO:0048511; GO:0080182; GO:0090575 12498 XM_044312381.1 11 2 3 0 29 NA NA NA NA NA NA 12499 XR_006393801.1 0 3 1 0 34 NA NA NA NA NA NA 12500 XM_044326419.1 25 11 31 34 100 NA NA NA NA NA NA 12501 XM_044314094.1 0 0 8 0 17 NA NA NA NA NA NA 12502 XM_044313471.1 49 8 7 7 119 NA NA NA NA NA NA 12503 XM_029339603.2 3644 2635 2139 3869 3334 Q6P2Q9 0 Pre-mRNA-processing-splicing factor 8 (220 kDa U5 snRNP-specific protein) (PRP8 homolog) (Splicing factor Prp8) (p220) Homo sapiens (Human) cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]; spliceosomal tri-snRNP complex assembly [GO:0000244] GO:0000244; GO:0000375; GO:0000398; GO:0003723; GO:0005634; GO:0005654; GO:0005682; GO:0006397; GO:0008380; GO:0016020; GO:0016607; GO:0017070; GO:0030619; GO:0030620; GO:0030623; GO:0046540; GO:0070530; GO:0071005; GO:0071006; GO:0071007; GO:0071013; GO:0071222; GO:0071356; GO:0097157 12504 XR_003826146.2 78 63 31 72 111 NA NA NA NA NA NA 12505 XM_044312827.1 44 15 22 11 35 Q925Q3 1.78e-97 Mitochondrial sodium/calcium exchanger protein (Na(+)/K(+)/Ca(2+)-exchange protein 6) (Sodium/calcium exchanger protein, mitochondrial) (Sodium/potassium/calcium exchanger 6) (Solute carrier family 24 member 6) (Solute carrier family 8 member B1) Mus musculus (Mouse) calcium export from the mitochondrion [GO:0099093]; calcium ion transmembrane transport [GO:0070588]; cation transport [GO:0006812]; cellular calcium ion homeostasis [GO:0006874]; glucose homeostasis [GO:0042593]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrial calcium ion transmembrane transport [GO:0006851]; regulation of cardiac muscle cell membrane potential [GO:0086036]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of insulin secretion [GO:0050796]; regulation of lymphocyte chemotaxis [GO:1901623]; regulation of store-operated calcium entry [GO:2001256]; response to stimulus [GO:0050896]; sodium ion transmembrane transport [GO:0035725] GO:0005432; GO:0005739; GO:0005743; GO:0005886; GO:0006812; GO:0006851; GO:0006874; GO:0008324; GO:0016020; GO:0030061; GO:0031966; GO:0035725; GO:0042383; GO:0042593; GO:0042802; GO:0042803; GO:0050796; GO:0050896; GO:0051480; GO:0051560; GO:0070588; GO:0086036; GO:0086038; GO:0099093; GO:1901623; GO:2001256 12506 XM_044318753.1 0 140 0 0 0 NA NA NA NA NA NA 12507 XM_044308791.1 0 8 0 0 17 NA NA NA NA NA NA 12508 XM_044320646.1 38 2 31 253 4 NA NA NA NA NA NA 12509 XM_044327287.1 10 62 24 81 41 NA NA NA NA NA NA 12510 XM_029338684.2 437 34 88 328 445 B3DL53 2.28e-47 Nucleoside diphosphate kinase 6 (NDK 6) (NDP kinase 6) (EC 2.7.4.6) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside diphosphate phosphorylation [GO:0006165]; UTP biosynthetic process [GO:0006228] GO:0004550; GO:0005524; GO:0006165; GO:0006183; GO:0006228; GO:0006241; GO:0046872 12511 XM_029329932.2 316 355 267 357 306 Q96AY4 2.99e-80 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12512 XM_029329932.2 316 355 267 357 306 Q96AY4 1.98e-78 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12513 XM_029329932.2 316 355 267 357 306 Q96AY4 1.99e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12514 XM_029329932.2 316 355 267 357 306 Q96AY4 3.15e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12515 XM_029329932.2 316 355 267 357 306 Q96AY4 9.85e-73 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12516 XM_029329932.2 316 355 267 357 306 Q96AY4 2.62e-70 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12517 XM_029329932.2 316 355 267 357 306 Q96AY4 4.88e-66 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12518 XM_029352261.2 7 16 18 37 37 NA NA NA NA NA NA 12519 XM_044321214.1 14 0 10 6 0 NA NA NA NA NA NA 12520 XR_006391629.1 148 47 106 0 167 NA NA NA NA NA NA 12521 XM_044320780.1 10 35 40 12 118 NA NA NA NA NA NA 12522 XM_029340200.2 230 146 195 164 344 NA NA NA NA NA NA 12523 XM_044314593.1 0 12 0 7 0 NA NA NA NA NA NA 12524 XM_029336630.2 310 464 355 325 244 Q86UW9 5.85e-84 Probable E3 ubiquitin-protein ligase DTX2 (EC 2.3.2.27) (Protein deltex-2) (Deltex2) (hDTX2) (RING finger protein 58) (RING-type E3 ubiquitin transferase DTX2) Homo sapiens (Human) Notch signaling pathway [GO:0007219]; protein ubiquitination [GO:0016567] GO:0005654; GO:0005737; GO:0007219; GO:0008270; GO:0016567; GO:0031965; GO:0061630 12525 XM_029336630.2 310 464 355 325 244 Q86UW9 4.35e-25 Probable E3 ubiquitin-protein ligase DTX2 (EC 2.3.2.27) (Protein deltex-2) (Deltex2) (hDTX2) (RING finger protein 58) (RING-type E3 ubiquitin transferase DTX2) Homo sapiens (Human) Notch signaling pathway [GO:0007219]; protein ubiquitination [GO:0016567] GO:0005654; GO:0005737; GO:0007219; GO:0008270; GO:0016567; GO:0031965; GO:0061630 12526 XM_044314022.1 6 4 0 0 28 NA NA NA NA NA NA 12527 XM_044319571.1 0 84 30 52 106 NA NA NA NA NA NA 12528 XM_029351620.2 17 19 15 5 77 NA NA NA NA NA NA 12529 XM_044325939.1 0 0 14 9 0 NA NA NA NA NA NA 12530 XM_044313407.1 77 14 34 9 155 NA NA NA NA NA NA 12531 XM_029335194.2 554 1074 496 354 483 Q9H6L4 1.9e-51 Armadillo repeat-containing protein 7 Homo sapiens (Human) NA NA 12532 XM_044323219.1 91 62 130 48 263 NA NA NA NA NA NA 12533 XM_029348581.2 14 0 28 11 6 NA NA NA NA NA NA 12534 XM_029329328.2 1392 1378 607 572 543 Q54JH4 3.42e-38 P2X receptor E (P2XE) Dictyostelium discoideum (Social amoeba) calcium ion transmembrane transport [GO:0070588]; cellular hypotonic response [GO:0071476]; ion transport [GO:0006811]; regulation of calcium-mediated signaling [GO:0050848] GO:0005524; GO:0006811; GO:0031164; GO:0035381; GO:0050848; GO:0070588; GO:0071476; GO:0140417 12535 XM_044314649.1 42 2 28 0 114 NA NA NA NA NA NA 12536 XR_006396762.1 71 176 87 160 126 NA NA NA NA NA NA 12537 XM_029347189.2 1617 647 608 1205 2006 Q60437 2.77e-21 Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI-associated protein 2) (BAI1-associated protein 2) (Insulin receptor substrate protein of 53 kDa) (IRSp53) (Insulin receptor substrate p53) (Insulin receptor tyrosine kinase 53 kDa substrate) (p58/p53) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) actin crosslink formation [GO:0051764]; actin filament bundle assembly [GO:0051017]; plasma membrane organization [GO:0007009]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; response to bacterium [GO:0009617] GO:0001726; GO:0005829; GO:0005856; GO:0007009; GO:0008360; GO:0009617; GO:0016020; GO:0030175; GO:0032956; GO:0051017; GO:0051764; GO:0070064 12538 XM_044328578.1 295 230 159 301 346 P51892 0 DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1) Xenopus laevis (African clawed frog) cell cycle [GO:0007049]; cell division [GO:0051301]; DNA biosynthetic process [GO:0071897]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260] GO:0003677; GO:0003910; GO:0005524; GO:0005634; GO:0006260; GO:0006281; GO:0006310; GO:0007049; GO:0046872; GO:0051301; GO:0071897 12539 XM_029331980.2 9 0 16 5 12 NA NA NA NA NA NA 12540 XM_044325972.1 764 797 741 1103 1120 NA NA NA NA NA NA 12541 XR_003823336.2 4 124 62 12 9 NA NA NA NA NA NA 12542 XM_044309467.1 1 1 0 41 0 Q9JKL7 3.48e-38 Splicing regulatory glutamine/lysine-rich protein 1 (SR-related protein of 86 kDa) (Serine/arginine-rich-splicing regulatory protein 86) (SRrp86) (Splicing factor, arginine/serine-rich 12) Rattus norvegicus (Rat) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0003723; GO:0005654; GO:0005681; GO:0006397; GO:0008380 12543 XM_029340111.2 1299 760 569 920 778 A6NCS4 1.13e-38 Homeobox protein Nkx-2.6 (Homeobox protein NK-2 homolog F) Homo sapiens (Human) atrial cardiac muscle cell development [GO:0055014]; cell differentiation [GO:0030154]; digestive tract development [GO:0048565]; embryonic heart tube development [GO:0035050]; epithelial cell apoptotic process [GO:1904019]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation [GO:0050673]; hypothalamus development [GO:0021854]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epithelial cell apoptotic process [GO:1904036]; pericardium development [GO:0060039]; pharyngeal system development [GO:0060037]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; tongue development [GO:0043586]; ventricular cardiac muscle cell development [GO:0055015] GO:0000785; GO:0000978; GO:0000981; GO:0001228; GO:0003700; GO:0005634; GO:0006357; GO:0008284; GO:0021854; GO:0030154; GO:0030855; GO:0035050; GO:0043066; GO:0043586; GO:0045944; GO:0048565; GO:0050673; GO:0050679; GO:0055014; GO:0055015; GO:0060037; GO:0060039; GO:1904019; GO:1904036 12544 XM_044316852.1 151 22 75 48 44 NA NA NA NA NA NA 12545 XM_029354012.2 1 12 18 42 3 NA NA NA NA NA NA 12546 XM_044309905.1 102 0 0 0 89 NA NA NA NA NA NA 12547 XM_029347714.2 188 67 76 93 156 Q800K6 1.37e-28 DNA topoisomerase 2-binding protein 1-A (Cut5 protein) (DNA topoisomerase II-binding protein 1-A) (TopBP1-A) (XtopBP) Xenopus laevis (African clawed frog) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA replication checkpoint signaling [GO:0000076]; DNA replication initiation [GO:0006270]; DNA replication preinitiation complex assembly [GO:0071163]; GINS complex assembly [GO:0071165]; positive regulation of chromatin binding [GO:0035563]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase activity [GO:0045860]; protein localization to chromatin [GO:0071168]; regulation of DNA-templated DNA replication initiation [GO:0030174] GO:0000076; GO:0000785; GO:0000922; GO:0003677; GO:0003682; GO:0005634; GO:0005737; GO:0005815; GO:0006270; GO:0006281; GO:0006974; GO:0019900; GO:0030174; GO:0033138; GO:0035563; GO:0045860; GO:0071163; GO:0071165; GO:0071168 12548 XM_029348856.2 728 261 723 786 76 O75081 4.11e-131 Protein CBFA2T3 (MTG8-related protein 2) (Myeloid translocation gene on chromosome 16 protein) (hMTG16) (Zinc finger MYND domain-containing protein 4) Homo sapiens (Human) granulocyte differentiation [GO:0030851]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of glycolytic process [GO:0045820]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; regulation of aerobic respiration [GO:1903715]; response to hypoxia [GO:0001666] GO:0000139; GO:0001666; GO:0003714; GO:0005634; GO:0005654; GO:0005730; GO:0008285; GO:0030851; GO:0032436; GO:0045820; GO:0045892; GO:0046872; GO:1903715 12549 XM_044326676.1 28 0 57 4 28 P04323 8.7e-62 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 12550 XM_029343493.2 570 189 184 235 289 A1DWM3 4.7e-30 Major facilitator superfamily domain-containing protein 6 (Macrophage MHC class I receptor 2 homolog) Sus scrofa (Pig) antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590] GO:0005886; GO:0016020; GO:0042590 12551 XM_044322897.1 47 12 48 2 80 NA NA NA NA NA NA 12552 XM_029357310.2 208 128 107 91 390 Q9UHJ6 6.13e-111 Sedoheptulokinase (SHK) (EC 2.7.1.14) (Carbohydrate kinase-like protein) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; cellular response to interleukin-13 [GO:0035963]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; glycerol metabolic process [GO:0006071]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; phosphorylation [GO:0016310]; regulation of inflammatory response [GO:0050727]; regulation of macrophage activation [GO:0043030] GO:0005524; GO:0005737; GO:0005829; GO:0005975; GO:0006071; GO:0006098; GO:0009052; GO:0016310; GO:0016773; GO:0035963; GO:0043030; GO:0050277; GO:0050727; GO:0071222; GO:0071353 12553 XM_044320330.1 0 0 0 12 0 NA NA NA NA NA NA 12554 XM_029339563.2 2024 2156 1036 1731 1300 Q17RD7 2.29e-75 Synaptotagmin-16 (Chr14Syt) (Synaptotagmin 14-like protein) (Synaptotagmin XIV-related protein) Homo sapiens (Human) NA GO:0005543; GO:0042802 12555 XM_044323101.1 305 161 155 471 669 O93484 1.58e-37 Collagen alpha-2(I) chain (Alpha-2 type I collagen) Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) NA GO:0005201; GO:0005576; GO:0005581; GO:0046872 12556 XR_006392710.1 0 12 0 0 2 NA NA NA NA NA NA 12557 XM_029342934.2 0 155 151 31 0 NA NA NA NA NA NA 12558 XM_029339216.2 801 601 212 442 353 Q5RDQ2 1.25e-162 Protein PALS1 (MAGUK p55 subfamily member 5) (Protein associated with Lin-7 1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) central nervous system neuron development [GO:0021954]; cerebral cortex development [GO:0021987]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015] GO:0005524; GO:0005794; GO:0005912; GO:0005923; GO:0016324; GO:0017015; GO:0021954; GO:0021987; GO:0030424; GO:0043204 12559 XR_003826449.2 21 19 56 55 103 NA NA NA NA NA NA 12560 XM_029329800.2 1110 425 622 1028 1439 Q9P2P6 4.56e-21 StAR-related lipid transfer protein 9 (START domain-containing protein 9) (StARD9) Homo sapiens (Human) microtubule-based movement [GO:0007018]; spindle assembly [GO:0051225] GO:0003777; GO:0005524; GO:0005634; GO:0005737; GO:0005814; GO:0007018; GO:0008017; GO:0008289; GO:0051225 12561 XM_029344527.2 252 196 0 68 159 Q568G4 3.63e-31 EF-hand calcium-binding domain-containing protein 11 Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005509 12562 XM_029348971.2 57 0 0 0 111 F1R8P4 4.05e-90 Glycine receptor subunit alpha-2 Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0004888; GO:0005254; GO:0016594; GO:0016933; GO:0022824; GO:0034707; GO:0042995; GO:0045211; GO:0046872 12563 XM_044321203.1 40 64 70 0 173 A6H603 9.83e-49 NACHT domain- and WD repeat-containing protein 1 Mus musculus (Mouse) negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of gene expression [GO:0010628] GO:0005524; GO:0005730; GO:0005829; GO:0010628; GO:0032088 12564 XM_044321203.1 40 64 70 0 173 A6H603 1.09e-34 NACHT domain- and WD repeat-containing protein 1 Mus musculus (Mouse) negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of gene expression [GO:0010628] GO:0005524; GO:0005730; GO:0005829; GO:0010628; GO:0032088 12565 XM_044316817.1 1583 912 1136 1690 1999 P38571 3.3e-131 Lysosomal acid lipase/cholesteryl ester hydrolase (Acid cholesteryl ester hydrolase) (LAL) (EC 3.1.1.13) (Cholesteryl esterase) (Lipase A) (Sterol esterase) Homo sapiens (Human) cell morphogenesis [GO:0000902]; epithelial cell proliferation [GO:0050673]; homeostasis of number of cells within a tissue [GO:0048873]; inflammatory response [GO:0006954]; lipid catabolic process [GO:0016042]; low-density lipoprotein particle clearance [GO:0034383]; lung development [GO:0030324]; macrophage homeostasis [GO:0061519]; sterol metabolic process [GO:0016125]; tissue remodeling [GO:0048771] GO:0000902; GO:0001650; GO:0004771; GO:0005654; GO:0005764; GO:0005829; GO:0006954; GO:0016042; GO:0016125; GO:0016298; GO:0030324; GO:0034383; GO:0043202; GO:0043231; GO:0048771; GO:0048873; GO:0050673; GO:0061519 12566 XM_029349322.2 1501 1343 990 1771 1919 Q13905 3.94e-110 Rap guanine nucleotide exchange factor 1 (CRK SH3-binding GNRP) (Guanine nucleotide-releasing factor 2) (Protein C3G) Homo sapiens (Human) cellular response to cAMP [GO:0071320]; cellular response to nerve growth factor stimulus [GO:1990090]; establishment of endothelial barrier [GO:0061028]; nerve growth factor signaling pathway [GO:0038180]; nervous system development [GO:0007399]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron projection development [GO:0010976]; Rap protein signal transduction [GO:0032486]; Ras protein signal transduction [GO:0007265]; regulation of cell junction assembly [GO:1901888]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0005085; GO:0005737; GO:0005769; GO:0005829; GO:0005886; GO:0007165; GO:0007169; GO:0007265; GO:0007399; GO:0010976; GO:0017124; GO:0032486; GO:0038180; GO:0043231; GO:0043547; GO:0061028; GO:0071320; GO:1901888; GO:1990090 12567 XM_044320024.1 703 490 593 714 758 Q9D0W5 5.76e-74 Peptidyl-prolyl cis-trans isomerase-like 1 (PPIase) (EC 5.2.1.8) (Rotamase PPIL1) Mus musculus (Mouse) embryonic brain development [GO:1990403]; mRNA splicing, via spliceosome [GO:0000398]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413] GO:0000398; GO:0000413; GO:0003755; GO:0005634; GO:0006457; GO:0016018; GO:0071007; GO:0071013; GO:0097718; GO:1990403 12568 XM_044314468.1 97 27 76 43 60 Q9VAC5 3.78e-39 ADAM 17-like protease (EC 3.4.24.-) Drosophila melanogaster (Fruit fly) membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; positive regulation of cell death [GO:0010942]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0004222; GO:0005886; GO:0006509; GO:0007219; GO:0007220; GO:0010942; GO:0016020; GO:0033209; GO:0040015; GO:0046872; GO:1903427 12569 XM_044321971.1 0 0 12 0 0 O75486 4.96e-64 Transcription initiation protein SPT3 homolog (SPT3-like protein) Homo sapiens (Human) histone acetylation [GO:0016573]; histone H3 acetylation [GO:0043966]; monoubiquitinated histone deubiquitination [GO:0035521]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA repair [GO:0006282]; regulation of DNA-templated transcription [GO:0006355]; regulation of RNA splicing [GO:0043484]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366] GO:0000124; GO:0003713; GO:0005634; GO:0005654; GO:0006282; GO:0006355; GO:0006357; GO:0006366; GO:0016573; GO:0033276; GO:0035521; GO:0035522; GO:0043484; GO:0043966; GO:0045893; GO:0046982 12570 XM_029331963.2 0 0 119 526 0 B3EWZ3 2.93e-103 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 12571 XM_029331963.2 0 0 119 526 0 B3EWZ3 3.4e-98 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 12572 XM_029331963.2 0 0 119 526 0 B3EWZ3 4.8e-96 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 12573 XM_029331963.2 0 0 119 526 0 B3EWZ3 1.77e-95 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 12574 XM_029331963.2 0 0 119 526 0 B3EWZ3 1.6e-94 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 12575 XM_029331963.2 0 0 119 526 0 B3EWZ3 1.14e-93 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 12576 XM_029331963.2 0 0 119 526 0 B3EWZ3 2.41e-87 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 12577 XM_029331963.2 0 0 119 526 0 B3EWZ3 1.83e-70 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 12578 XM_029331963.2 0 0 119 526 0 B3EWZ3 2.75e-24 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 12579 XM_029336261.2 44 21 33 56 53 O88854 6.5e-46 Galanin receptor type 2 (GAL2-R) (GALR-2) Mus musculus (Mouse) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; G protein-coupled receptor signaling pathway [GO:0007186]; galanin-activated signaling pathway [GO:0090663]; inositol phosphate metabolic process [GO:0043647]; negative regulation of adenylate cyclase activity [GO:0007194]; neuron projection development [GO:0031175]; neuropeptide signaling pathway [GO:0007218]; phosphatidylinositol metabolic process [GO:0046488]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of large conductance calcium-activated potassium channel activity [GO:1902608]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0004966; GO:0005886; GO:0005929; GO:0007186; GO:0007188; GO:0007189; GO:0007194; GO:0007200; GO:0007204; GO:0007218; GO:0008528; GO:0017046; GO:0031175; GO:0042923; GO:0043647; GO:0045944; GO:0046488; GO:0090663; GO:1902608 12580 XM_029330612.2 14 18 0 26 16 Q9QY96 2.03e-95 Extracellular calcium-sensing receptor (CaSR) (Parathyroid cell calcium-sensing receptor) (PCaR1) Mus musculus (Mouse) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; apoptotic process [GO:0006915]; bile acid secretion [GO:0032782]; branching morphogenesis of an epithelial tube [GO:0048754]; calcium ion import [GO:0070509]; cellular calcium ion homeostasis [GO:0006874]; cellular response to glucose stimulus [GO:0071333]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hypoxia [GO:0071456]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to peptide [GO:1901653]; cellular response to vitamin D [GO:0071305]; chloride transmembrane transport [GO:1902476]; detection of calcium ion [GO:0005513]; fat pad development [GO:0060613]; G protein-coupled receptor signaling pathway [GO:0007186]; JNK cascade [GO:0007254]; ossification [GO:0001503]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of ATP-dependent activity [GO:0032781]; positive regulation of calcium ion import [GO:0090280]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin secretion [GO:0032024]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of vasoconstriction [GO:0045907]; regulation of calcium ion transport [GO:0051924]; response to fibroblast growth factor [GO:0071774]; response to ischemia [GO:0002931]; vasodilation [GO:0042311] GO:0001503; GO:0002931; GO:0004930; GO:0005178; GO:0005509; GO:0005513; GO:0005634; GO:0005737; GO:0005886; GO:0006874; GO:0006915; GO:0007186; GO:0007193; GO:0007200; GO:0007254; GO:0008284; GO:0009986; GO:0010628; GO:0016020; GO:0016323; GO:0016324; GO:0016597; GO:0019901; GO:0030424; GO:0032024; GO:0032781; GO:0032782; GO:0035729; GO:0042311; GO:0042802; GO:0042803; GO:0043005; GO:0043025; GO:0043679; GO:0044325; GO:0045907; GO:0048754; GO:0050927; GO:0051924; GO:0060613; GO:0070374; GO:0070509; GO:0071305; GO:0071333; GO:0071404; GO:0071456; GO:0071774; GO:0090280; GO:1901653; GO:1902476 12581 XM_044317893.1 152 93 121 162 370 P22770 4.13e-65 Neuronal acetylcholine receptor subunit alpha-7 Gallus gallus (Chicken) calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; cognition [GO:0050890]; membrane depolarization [GO:0051899]; negative regulation of tumor necrosis factor production [GO:0032720]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAPK cascade [GO:0043410]; regulation of nitric oxide metabolic process [GO:0080164]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; signal transduction [GO:0007165] GO:0001540; GO:0001666; GO:0005737; GO:0005886; GO:0005892; GO:0006816; GO:0006874; GO:0007165; GO:0008284; GO:0015464; GO:0015643; GO:0017081; GO:0022848; GO:0030424; GO:0030425; GO:0032720; GO:0035094; GO:0042166; GO:0042803; GO:0043204; GO:0043410; GO:0045211; GO:0045766; GO:0050890; GO:0051899; GO:0080164 12582 XM_044324250.1 0 44 7 0 0 Q4R6I5 4.3e-27 Clathrin heavy chain linker domain-containing protein 1 Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA NA 12583 XM_044318213.1 0 4 10 3 0 NA NA NA NA NA NA 12584 XR_006393347.1 38 0 0 2 32 NA NA NA NA NA NA 12585 XM_029346760.2 54 240 50 320 312 NA NA NA NA NA NA 12586 XM_044312742.1 4300 3038 2062 5586 1571 NA NA NA NA NA NA 12587 XM_029335980.2 984 1032 228 858 1179 Q502L2 7.19e-76 Serine/threonine-protein phosphatase PGAM5, mitochondrial (EC 3.1.3.16) (Phosphoglycerate mutase family member 5) Danio rerio (Zebrafish) (Brachydanio rerio) peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of mitochondrial fission [GO:0090141]; programmed cell death [GO:0012501] GO:0004722; GO:0005739; GO:0005741; GO:0012501; GO:0017018; GO:0035970; GO:0090141 12588 XM_044328194.1 30 13 25 3 24 NA NA NA NA NA NA 12589 XM_029331527.2 98 162 89 120 203 Q8R123 2.25e-137 FAD synthase (EC 2.7.7.2) (FAD pyrophosphorylase) (FMN adenylyltransferase) (Flavin adenine dinucleotide synthase) [Includes: Molybdenum cofactor biosynthesis protein-like region; FAD synthase region] Mus musculus (Mouse) FAD biosynthetic process [GO:0006747] GO:0003919; GO:0005524; GO:0005829; GO:0005886; GO:0006747; GO:0042802 12590 XM_044315184.1 0 7 2 0 19 NA NA NA NA NA NA 12591 XM_029330035.2 7 9 0 4 19 NA NA NA NA NA NA 12592 XM_044313069.1 348 319 821 635 26 Q5U2V4 3.49e-173 Phospholipase B-like 1 (EC 3.1.1.-) (LAMA-like protein 1) (Lamina ancestor homolog 1) (Phospholipase B domain-containing protein 1) [Cleaved into: Phospholipase B-like 1 chain A; Phospholipase B-like 1 chain B; Phospholipase B-like 1 chain C] Rattus norvegicus (Rat) phospholipid catabolic process [GO:0009395] GO:0004620; GO:0005576; GO:0005615; GO:0005764; GO:0009395 12593 XR_003824214.2 442 311 342 391 512 NA NA NA NA NA NA 12594 XM_029344576.2 2228 1563 1185 2156 2662 Q924X7 8e-122 Serine/threonine-protein kinase 33 (EC 2.7.11.1) Mus musculus (Mouse) mitotic DNA damage checkpoint signaling [GO:0044773]; protein autophosphorylation [GO:0046777] GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0044773; GO:0046777; GO:0048471; GO:0106310 12595 XM_029357424.2 423 208 150 370 416 A5PJI7 1.47e-121 Translation initiation factor eIF-2B subunit gamma (eIF-2B GDP-GTP exchange factor subunit gamma) Bos taurus (Bovine) oligodendrocyte development [GO:0014003]; T cell receptor signaling pathway [GO:0050852]; translational initiation [GO:0006413] GO:0003743; GO:0005737; GO:0005851; GO:0006413; GO:0014003; GO:0016779; GO:0050852 12596 XR_006396607.1 0 10 1 6 59 NA NA NA NA NA NA 12597 XR_003825211.2 3 0 12 0 78 NA NA NA NA NA NA 12598 XM_044317832.1 23 3 9 25 30 NA NA NA NA NA NA 12599 XM_029324015.2 822 2392 545 1558 1356 NA NA NA NA NA NA 12600 XM_044317423.1 245 0 31 115 74 NA NA NA NA NA NA 12601 XM_029328842.2 3013 2506 1573 1597 1972 B2RYG1 1.17e-28 Protein FAM32A (Ovarian tumor associated gene 12) (OTAG-12) Rattus norvegicus (Rat) apoptotic process [GO:0006915]; cell cycle [GO:0007049] GO:0005730; GO:0006915; GO:0007049 12602 XM_029336221.2 1076 1128 983 1862 1115 P54417 1.36e-100 Glycine betaine transporter OpuD Bacillus subtilis (strain 168) glycine betaine transport [GO:0031460] GO:0005886; GO:0016020; GO:0022857; GO:0031460 12603 XM_029333786.2 16 0 79 45 85 Q6IR75 0 COP9 signalosome complex subunit 2 (Signalosome subunit 2) Xenopus laevis (African clawed frog) NA GO:0005737; GO:0008180 12604 XR_006392986.1 41 2 25 5 151 NA NA NA NA NA NA 12605 XR_003827429.2 85 105 77 60 152 NA NA NA NA NA NA 12606 XM_029336611.2 6324 6092 2826 4535 4363 Q15382 1.27e-80 GTP-binding protein Rheb (Ras homolog enriched in brain) Homo sapiens (Human) negative regulation of cold-induced thermogenesis [GO:0120163]; oligodendrocyte differentiation [GO:0048709]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of TOR signaling [GO:0032008]; regulation of cell cycle [GO:0051726]; regulation of macroautophagy [GO:0016241]; regulation of type B pancreatic cell development [GO:2000074]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264] GO:0000139; GO:0000287; GO:0003924; GO:0005525; GO:0005681; GO:0005765; GO:0005789; GO:0005829; GO:0005886; GO:0007165; GO:0007264; GO:0014069; GO:0016020; GO:0016241; GO:0019003; GO:0019901; GO:0032008; GO:0048709; GO:0048714; GO:0051726; GO:0070062; GO:0120163; GO:2000074 12607 XM_044322557.1 15 0 0 0 0 Q94887 1.62e-32 Neurexin-4 (Neurexin IV) Drosophila melanogaster (Fruit fly) axon ensheathment [GO:0008366]; cell adhesion involved in heart morphogenesis [GO:0061343]; cell-cell junction organization [GO:0045216]; dorsal closure [GO:0007391]; establishment of glial blood-brain barrier [GO:0060857]; heart process [GO:0003015]; nerve maturation [GO:0021682]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]; synaptic target recognition [GO:0008039]; terminal button organization [GO:0072553] GO:0003015; GO:0005886; GO:0005919; GO:0007391; GO:0008039; GO:0008104; GO:0008366; GO:0019991; GO:0021682; GO:0035151; GO:0045202; GO:0045216; GO:0048786; GO:0060857; GO:0061343; GO:0072553; GO:0097105 12608 XM_029356332.2 351 253 295 197 294 NA NA NA NA NA NA 12609 XM_044316746.1 4 0 9 0 1 P79218 2.36e-40 Substance-K receptor (SKR) (NK-2 receptor) (NK-2R) (Neurokinin A receptor) (Tachykinin receptor 2) Oryctolagus cuniculus (Rabbit) positive regulation of flagellated sperm motility [GO:1902093]; regulation of uterine smooth muscle contraction [GO:0070472] GO:0004995; GO:0005886; GO:0061827; GO:0070472; GO:0097225; GO:1902093 12610 XR_006394385.1 0 0 51 91 63 NA NA NA NA NA NA 12611 XM_029336739.2 1687 1238 748 1757 1489 Q9BZ72 0 Membrane-associated phosphatidylinositol transfer protein 2 (Phosphatidylinositol transfer protein, membrane-associated 2) (PITPnm 2) (Pyk2 N-terminal domain-interacting receptor 3) (NIR-3) Homo sapiens (Human) phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol-mediated signaling [GO:0048015] GO:0005509; GO:0005737; GO:0005829; GO:0006661; GO:0008525; GO:0008526; GO:0012505; GO:0016020; GO:0030971; GO:0031210; GO:0035091; GO:0048015 12612 XM_029336739.2 1687 1238 748 1757 1489 Q9BZ72 1.1e-110 Membrane-associated phosphatidylinositol transfer protein 2 (Phosphatidylinositol transfer protein, membrane-associated 2) (PITPnm 2) (Pyk2 N-terminal domain-interacting receptor 3) (NIR-3) Homo sapiens (Human) phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol-mediated signaling [GO:0048015] GO:0005509; GO:0005737; GO:0005829; GO:0006661; GO:0008525; GO:0008526; GO:0012505; GO:0016020; GO:0030971; GO:0031210; GO:0035091; GO:0048015 12613 XM_029332078.2 1 58 160 4 25 NA NA NA NA NA NA 12614 XM_044315813.1 7 5 0 32 11 P04323 5.3e-72 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 12615 XM_029351232.2 6 0 9 2 21 NA NA NA NA NA NA 12616 XM_044317140.1 0 0 45 0 86 NA NA NA NA NA NA 12617 XR_006397344.1 20 32 11 27 53 NA NA NA NA NA NA 12618 XR_003826647.2 66 60 124 59 178 NA NA NA NA NA NA 12619 XM_044317604.1 0 0 1 0 16 P15043 1.47e-42 ATP-dependent DNA helicase RecQ (EC 3.6.4.12) Escherichia coli (strain K12) cellular response to DNA damage stimulus [GO:0006974]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; SOS response [GO:0009432] GO:0003677; GO:0003678; GO:0005524; GO:0005694; GO:0005737; GO:0006260; GO:0006281; GO:0006310; GO:0006974; GO:0008094; GO:0008270; GO:0009378; GO:0009432; GO:0016887; GO:0017116; GO:0017117; GO:0030894; GO:0032508; GO:0043138; GO:0043590; GO:0046914 12620 XM_044317604.1 0 0 1 0 16 P15043 1.47e-42 ATP-dependent DNA helicase RecQ (EC 3.6.4.12) Escherichia coli (strain K12) cellular response to DNA damage stimulus [GO:0006974]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; SOS response [GO:0009432] GO:0003677; GO:0003678; GO:0005524; GO:0005694; GO:0005737; GO:0006260; GO:0006281; GO:0006310; GO:0006974; GO:0008094; GO:0008270; GO:0009378; GO:0009432; GO:0016887; GO:0017116; GO:0017117; GO:0030894; GO:0032508; GO:0043138; GO:0043590; GO:0046914 12621 XR_006397355.1 361 188 97 170 186 Q2TBK4 6.72e-24 HAUS augmin-like complex subunit 1 (Coiled-coil domain-containing protein 5) Bos taurus (Bovine) cell division [GO:0051301]; centrosome cycle [GO:0007098]; spindle assembly [GO:0051225] GO:0000922; GO:0005813; GO:0005829; GO:0007098; GO:0051225; GO:0051301; GO:0070652; GO:1990498 12622 XM_044316593.1 162 89 84 154 186 Q9BPX3 0 Condensin complex subunit 3 (Chromosome-associated protein G) (Condensin subunit CAP-G) (hCAP-G) (Melanoma antigen NY-MEL-3) (Non-SMC condensin I complex subunit G) (XCAP-G homolog) Homo sapiens (Human) cell division [GO:0051301]; mitotic chromosome condensation [GO:0007076]; positive regulation of chromosome condensation [GO:1905821]; positive regulation of chromosome segregation [GO:0051984]; positive regulation of chromosome separation [GO:1905820] GO:0000779; GO:0000793; GO:0000794; GO:0000796; GO:0005634; GO:0005737; GO:0005829; GO:0007076; GO:0016020; GO:0051301; GO:0051984; GO:1905820; GO:1905821 12623 XM_044308192.1 0 106 0 0 0 Q9V9A7 2.74e-166 Probable methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCase subunit beta) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 2) (3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta) Drosophila melanogaster (Fruit fly) coenzyme A metabolic process [GO:0015936]; leucine catabolic process [GO:0006552]; regulation of eclosion [GO:0007563] GO:0004485; GO:0005524; GO:0005739; GO:0005759; GO:0006552; GO:0007563; GO:0015936; GO:1905202 12624 XM_044311485.1 11 39 3 6 0 NA NA NA NA NA NA 12625 XM_044316704.1 0 0 24 0 0 NA NA NA NA NA NA 12626 XM_044316202.1 161 61 86 85 93 NA NA NA NA NA NA 12627 XM_029343424.2 10 1 10 47 47 Q09575 2.79e-36 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 12628 XM_044314012.1 6 1 0 1 12 NA NA NA NA NA NA 12629 XM_029331425.2 1016 652 583 406 1473 Q5RFT1 2.72e-49 Solute carrier family 35 member F6 (ANT2-binding protein) (ANT2BP) (Transport and Golgi organization 9 homolog) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; positive regulation of cell population proliferation [GO:0008284] GO:0005739; GO:0005765; GO:0008284; GO:0022857; GO:1901029 12630 XM_029330206.2 74 140 0 58 0 NA NA NA NA NA NA 12631 XM_044312796.1 35 1554 0 537 313 Q4KLE6 1.14e-74 N-terminal Xaa-Pro-Lys N-methyltransferase 1-B (EC 2.1.1.244) (Alpha N-terminal protein methyltransferase 1A-B) (Methyltransferase-like protein 11A-B) (X-Pro-Lys N-terminal protein methyltransferase 1A-B) (NTM1A-B) Xenopus laevis (African clawed frog) chromosome segregation [GO:0007059]; histone methylation [GO:0016571]; N-terminal peptidyl-glycine methylation [GO:0018013]; N-terminal peptidyl-proline dimethylation [GO:0018016]; N-terminal peptidyl-serine dimethylation [GO:0035572]; N-terminal peptidyl-serine trimethylation [GO:0035573]; spindle organization [GO:0007051] GO:0005634; GO:0007051; GO:0007059; GO:0008276; GO:0016571; GO:0018013; GO:0018016; GO:0035572; GO:0035573; GO:0042054; GO:0071885 12632 XM_044318572.1 93 89 13 84 0 Q68F72 4.88e-83 Solute carrier family 15 member 4 Xenopus laevis (African clawed frog) dipeptide import across plasma membrane [GO:0140206]; innate immune response [GO:0045087]; mast cell homeostasis [GO:0033023]; peptidoglycan transport [GO:0015835]; positive regulation of innate immune response [GO:0045089]; positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [GO:0070430]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of toll-like receptor 7 signaling pathway [GO:0034157]; positive regulation of toll-like receptor 8 signaling pathway [GO:0034161]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; protein transport [GO:0015031]; regulation of isotype switching to IgG isotypes [GO:0048302]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424] GO:0005290; GO:0005765; GO:0015031; GO:0015333; GO:0015647; GO:0015835; GO:0031901; GO:0033023; GO:0034157; GO:0034161; GO:0034165; GO:0036020; GO:0045087; GO:0045089; GO:0048302; GO:0070424; GO:0070430; GO:0070434; GO:0071916; GO:0140206 12633 XM_044310615.1 229 94 213 161 154 NA NA NA NA NA NA 12634 XR_003823312.2 13 0 0 0 10 NA NA NA NA NA NA 12635 XM_044307864.1 102 36 49 62 44 NA NA NA NA NA NA 12636 XR_006392389.1 523 296 535 831 884 Q5F364 0 Multidrug resistance-associated protein 1 (EC 7.6.2.2) (ATP-binding cassette sub-family C member 1) (Glutathione-S-conjugate-translocating ATPase ABCC1) (EC 7.6.2.3) (Leukotriene C(4) transporter) (LTC4 transporter) Gallus gallus (Chicken) glutathione transmembrane transport [GO:0034775]; lipid transport [GO:0006869]; transmembrane transport [GO:0055085]; xenobiotic transport [GO:0042908] GO:0005524; GO:0006869; GO:0008559; GO:0016020; GO:0016323; GO:0016887; GO:0034634; GO:0034775; GO:0042626; GO:0042908; GO:0055085 12637 XR_006392389.1 523 296 535 831 884 Q5F364 0 Multidrug resistance-associated protein 1 (EC 7.6.2.2) (ATP-binding cassette sub-family C member 1) (Glutathione-S-conjugate-translocating ATPase ABCC1) (EC 7.6.2.3) (Leukotriene C(4) transporter) (LTC4 transporter) Gallus gallus (Chicken) glutathione transmembrane transport [GO:0034775]; lipid transport [GO:0006869]; transmembrane transport [GO:0055085]; xenobiotic transport [GO:0042908] GO:0005524; GO:0006869; GO:0008559; GO:0016020; GO:0016323; GO:0016887; GO:0034634; GO:0034775; GO:0042626; GO:0042908; GO:0055085 12638 XM_044319779.1 299 236 363 246 423 Q5ZLC8 3.89e-27 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (PP6-ARS-C) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C) Gallus gallus (Chicken) protein localization to T-tubule [GO:0036371]; regulation of cardiac muscle contraction [GO:0055117] GO:0030315; GO:0036371; GO:0055117 12639 XM_029356128.2 72 321 22 236 45 NA NA NA NA NA NA 12640 XM_029340549.2 326 2920 366 931 228 Q90X67 6.65e-26 Suppressor of cytokine signaling 3 (SOCS-3) Gallus gallus (Chicken) intracellular signal transduction [GO:0035556]; negative regulation of signal transduction [GO:0009968]; phosphatidylinositol phosphate biosynthetic process [GO:0046854]; protein ubiquitination [GO:0016567] GO:0005942; GO:0009968; GO:0016567; GO:0035556; GO:0046854; GO:0046935 12641 XM_044309130.1 0 83 71 96 0 NA NA NA NA NA NA 12642 XM_029343352.2 326 240 131 382 212 Q8R3G1 2.72e-106 Nuclear inhibitor of protein phosphatase 1 (NIPP-1) (Protein phosphatase 1 regulatory inhibitor subunit 8) Mus musculus (Mouse) cell population proliferation [GO:0008283]; mRNA processing [GO:0006397]; negative regulation of protein dephosphorylation [GO:0035308]; RNA splicing [GO:0008380] GO:0003677; GO:0003729; GO:0004865; GO:0005654; GO:0005681; GO:0006397; GO:0008283; GO:0008380; GO:0016607; GO:0019888; GO:0035308; GO:0140678 12643 XM_044326247.1 6 10 8 3 24 NA NA NA NA NA NA 12644 XR_006391440.1 0 11 0 0 0 NA NA NA NA NA NA 12645 XM_044313632.1 402 109 134 174 267 Q6DG03 2.87e-50 Cyclin-D-binding Myb-like transcription factor 1 Danio rerio (Zebrafish) (Brachydanio rerio) cell cycle [GO:0007049]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000976; GO:0000978; GO:0000981; GO:0003700; GO:0005634; GO:0006355; GO:0006357; GO:0007049 12646 XM_044309408.1 0 0 0 0 7 NA NA NA NA NA NA 12647 XM_029339776.1 567 437 423 817 357 O35900 1.32e-54 U6 snRNA-associated Sm-like protein LSm2 (Protein G7b) (snRNP core Sm-like protein Sm-x5) Mus musculus (Mouse) mRNA catabolic process [GO:0006402]; mRNA splicing, via spliceosome [GO:0000398]; spliceosomal tri-snRNP complex assembly [GO:0000244] GO:0000244; GO:0000398; GO:0000932; GO:0003723; GO:0005634; GO:0005654; GO:0005688; GO:0005737; GO:0006402; GO:0019901; GO:0031267; GO:0046540; GO:0071005; GO:0071011; GO:0071013; GO:0120115; GO:1990726 12648 XM_029338618.2 543 284 385 475 600 Q5RCQ9 6.22e-32 Kelch-like protein 23 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA NA 12649 XM_029340790.2 7867 10354 4975 6790 5950 Q28IL6 1.96e-31 60S ribosomal protein L22 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) translation [GO:0006412] GO:0003735; GO:0005737; GO:0005840; GO:0006412; GO:1990904 12650 XM_029348046.2 204 114 45 537 0 A8MU46 6.94e-26 Smoothelin-like protein 1 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; muscle organ morphogenesis [GO:0048644]; negative regulation of DNA-templated transcription [GO:0045892]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of vasoconstriction [GO:0045907]; response to activity [GO:0014823]; response to xenobiotic stimulus [GO:0009410]; vasoconstriction [GO:0042310] GO:0005516; GO:0005523; GO:0005634; GO:0005737; GO:0005815; GO:0008157; GO:0009410; GO:0014823; GO:0018105; GO:0030036; GO:0031430; GO:0031674; GO:0031941; GO:0042310; GO:0043292; GO:0043621; GO:0045892; GO:0045907; GO:0048644; GO:0051401; GO:0097718 12651 XM_044319515.1 21 0 7 3 55 NA NA NA NA NA NA 12652 XM_044310145.1 116 274 73 30 143 Q96MB7 5.17e-63 Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease) Homo sapiens (Human) NA GO:0004518; GO:0005634; GO:0005829; GO:0005886; GO:0034451; GO:0046872 12653 XM_044311756.1 0 24 37 4 0 A8WG43 3.6e-36 Coiled-coil domain-containing protein 89 (Bc8 orange-interacting protein) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005634; GO:0005737 12654 XM_029356886.2 10 0 0 0 2 P61752 4.49e-30 Histamine H2 receptor (H2R) (HH2R) (Gastric receptor I) Pongo pygmaeus (Bornean orangutan) gastric acid secretion [GO:0001696]; positive regulation of vasoconstriction [GO:0045907] GO:0001696; GO:0004969; GO:0005886; GO:0045907 12655 XM_029342919.2 864 852 682 801 948 Q6NUQ1 5.44e-158 RAD50-interacting protein 1 (RAD50 interactor 1) (HsRINT-1) (RINT-1) Homo sapiens (Human) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; protein transport [GO:0015031]; regulation of ER to Golgi vesicle-mediated transport [GO:0060628]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] GO:0005783; GO:0005789; GO:0005829; GO:0006888; GO:0006890; GO:0007095; GO:0015031; GO:0060628; GO:0070939 12656 XM_029330263.2 2564 3529 4248 6904 3639 O70597 6.06e-24 Peroxisomal membrane protein 11A (28 kDa peroxisomal integral membrane protein) (PMP28) (Peroxin-11A) (Peroxisomal biogenesis factor 11A) (Peroxisomal coatomer receptor) (Peroxisomal membrane protein 26) (Pmp26p) (Protein PEX11 homolog alpha) (PEX11-alpha) (RnPEX11p) Rattus norvegicus (Rat) brown fat cell differentiation [GO:0050873]; peroxisome fission [GO:0016559]; peroxisome membrane biogenesis [GO:0016557]; peroxisome organization [GO:0007031]; regulation of peroxisome size [GO:0044375]; signal transduction [GO:0007165] GO:0005777; GO:0005778; GO:0007031; GO:0007165; GO:0016557; GO:0016559; GO:0032991; GO:0042803; GO:0044375; GO:0050873 12657 XM_044317761.1 0 13 0 0 0 O43435 3.09e-101 T-box transcription factor TBX1 (T-box protein 1) (Testis-specific T-box protein) Homo sapiens (Human) angiogenesis [GO:0001525]; anterior/posterior pattern specification [GO:0009952]; aorta morphogenesis [GO:0035909]; artery morphogenesis [GO:0048844]; blood vessel development [GO:0001568]; blood vessel morphogenesis [GO:0048514]; cell fate specification [GO:0001708]; cell population proliferation [GO:0008283]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to retinoic acid [GO:0071300]; cochlea morphogenesis [GO:0090103]; coronary artery morphogenesis [GO:0060982]; determination of left/right symmetry [GO:0007368]; ear morphogenesis [GO:0042471]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic viscerocranium morphogenesis [GO:0048703]; enamel mineralization [GO:0070166]; epithelial cell differentiation [GO:0030855]; face morphogenesis [GO:0060325]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; inner ear morphogenesis [GO:0042472]; lymph vessel development [GO:0001945]; mesenchymal cell apoptotic process [GO:0097152]; mesoderm development [GO:0007498]; middle ear morphogenesis [GO:0042474]; muscle cell fate commitment [GO:0042693]; muscle organ development [GO:0007517]; muscle organ morphogenesis [GO:0048644]; muscle tissue morphogenesis [GO:0060415]; negative regulation of cell differentiation [GO:0045596]; negative regulation of mesenchymal cell apoptotic process [GO:2001054]; neural crest cell migration [GO:0001755]; odontogenesis of dentin-containing tooth [GO:0042475]; outer ear morphogenesis [GO:0042473]; outflow tract morphogenesis [GO:0003151]; outflow tract septum morphogenesis [GO:0003148]; parathyroid gland development [GO:0060017]; pattern specification process [GO:0007389]; pharyngeal system development [GO:0060037]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of tongue muscle cell differentiation [GO:2001037]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of animal organ morphogenesis [GO:2000027]; regulation of transcription by RNA polymerase II [GO:0006357]; retinoic acid receptor signaling pathway [GO:0048384]; semicircular canal morphogenesis [GO:0048752]; sensory perception of sound [GO:0007605]; social behavior [GO:0035176]; soft palate development [GO:0060023]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; tongue morphogenesis [GO:0043587]; vagus nerve morphogenesis [GO:0021644] GO:0000785; GO:0000978; GO:0000981; GO:0001525; GO:0001568; GO:0001708; GO:0001755; GO:0001934; GO:0001945; GO:0002053; GO:0003007; GO:0003148; GO:0003151; GO:0003677; GO:0005634; GO:0006357; GO:0007368; GO:0007389; GO:0007498; GO:0007507; GO:0007517; GO:0007605; GO:0008283; GO:0008284; GO:0009952; GO:0021644; GO:0030855; GO:0030878; GO:0035176; GO:0035909; GO:0042471; GO:0042472; GO:0042473; GO:0042474; GO:0042475; GO:0042693; GO:0042803; GO:0043410; GO:0043565; GO:0043587; GO:0044344; GO:0045596; GO:0045893; GO:0045944; GO:0046983; GO:0048384; GO:0048514; GO:0048538; GO:0048644; GO:0048701; GO:0048703; GO:0048752; GO:0048844; GO:0050679; GO:0060017; GO:0060023; GO:0060037; GO:0060325; GO:0060415; GO:0060982; GO:0070166; GO:0071300; GO:0090103; GO:0097152; GO:1990837; GO:2000027; GO:2001037; GO:2001054 12658 XM_029352033.2 0 0 14 0 0 NA NA NA NA NA NA 12659 XM_044327724.1 240 283 272 554 530 Q5ZHV5 2.23e-129 2-oxoglutarate and iron-dependent oxygenase JMJD4 (EC 1.14.11.-) (JmjC domain-containing protein 4) (Jumonji domain-containing protein 4) (Lysyl-hydroxylase JMJD4) Gallus gallus (Chicken) negative regulation of gene expression [GO:0010629]; positive regulation of translational termination [GO:0045905]; protein hydroxylation [GO:0018126] GO:0005634; GO:0005737; GO:0010629; GO:0016706; GO:0018126; GO:0043565; GO:0045905; GO:0046872; GO:0106156 12660 XM_044307752.1 0 0 18 0 0 Q6R5J2 0 Protein dispatched homolog 1 (Protein chameleon) Danio rerio (Zebrafish) (Brachydanio rerio) adenohypophysis development [GO:0021984]; animal organ morphogenesis [GO:0009887]; anterior/posterior pattern specification [GO:0009952]; blood circulation [GO:0008015]; embryonic cranial skeleton morphogenesis [GO:0048701]; inner ear development [GO:0048839]; muscle cell fate specification [GO:0042694]; retinal ganglion cell axon guidance [GO:0031290]; skeletal muscle tissue development [GO:0007519]; smoothened signaling pathway [GO:0007224]; transmembrane transport [GO:0055085] GO:0007224; GO:0007519; GO:0008015; GO:0009887; GO:0009952; GO:0016020; GO:0021984; GO:0022857; GO:0031290; GO:0042694; GO:0048701; GO:0048839; GO:0055085; GO:1904680 12661 XM_044308253.1 0 1 2 2 13 NA NA NA NA NA NA 12662 XM_044319368.1 10 8 2 8 9 Q8BSL4 2e-76 Heparan sulfate glucosamine 3-O-sulfotransferase 5 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5) (Heparan sulfate 3-O-sulfotransferase 5) Mus musculus (Mouse) heparan sulfate proteoglycan biosynthetic process [GO:0015012]; heparan sulfate proteoglycan biosynthetic process, enzymatic modification [GO:0015015]; negative regulation of coagulation [GO:0050819]; protein sulfation [GO:0006477]; regulation of viral entry into host cell [GO:0046596] GO:0000139; GO:0006477; GO:0008467; GO:0015012; GO:0015015; GO:0046596; GO:0050819 12663 XM_044322785.1 126 47 91 169 210 P78357 6.95e-29 Contactin-associated protein 1 (Caspr) (Caspr1) (Neurexin IV) (Neurexin-4) (p190) Homo sapiens (Human) axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cytoskeleton organization [GO:0007010]; mitochondrion organization [GO:0007005]; myelination in peripheral nervous system [GO:0022011]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; neuron projection morphogenesis [GO:0048812]; neuronal action potential propagation [GO:0019227]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; postsynaptic density organization [GO:0097106]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; regulation of synapse maturation [GO:0090128]; signal transduction [GO:0007165] GO:0002175; GO:0005886; GO:0007005; GO:0007010; GO:0007155; GO:0007165; GO:0007409; GO:0016020; GO:0017124; GO:0019227; GO:0022010; GO:0022011; GO:0030913; GO:0033010; GO:0033270; GO:0038023; GO:0048786; GO:0048812; GO:0050884; GO:0050885; GO:0071205; GO:0090128; GO:0097106; GO:0098529; GO:0098978; GO:1990227 12664 XM_044310978.1 0 0 0 0 6 NA NA NA NA NA NA 12665 XM_044313955.1 5 14 21 0 64 NA NA NA NA NA NA 12666 XM_044328493.1 0 50 0 0 0 Q8CEE6 4.73e-116 PAS domain-containing serine/threonine-protein kinase (PAS-kinase) (PASKIN) (EC 2.7.11.1) Mus musculus (Mouse) energy homeostasis [GO:0097009]; intracellular signal transduction [GO:0035556]; negative regulation of glycogen biosynthetic process [GO:0045719]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of glucagon secretion [GO:0070092]; regulation of respiratory gaseous exchange [GO:0043576] GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006468; GO:0035091; GO:0035556; GO:0043576; GO:0045719; GO:0046777; GO:0070092; GO:0097009; GO:0106310 12667 XM_044328493.1 0 50 0 0 0 Q8CEE6 2.87e-63 PAS domain-containing serine/threonine-protein kinase (PAS-kinase) (PASKIN) (EC 2.7.11.1) Mus musculus (Mouse) energy homeostasis [GO:0097009]; intracellular signal transduction [GO:0035556]; negative regulation of glycogen biosynthetic process [GO:0045719]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of glucagon secretion [GO:0070092]; regulation of respiratory gaseous exchange [GO:0043576] GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006468; GO:0035091; GO:0035556; GO:0043576; GO:0045719; GO:0046777; GO:0070092; GO:0097009; GO:0106310 12668 XM_044311572.1 24 24 4 0 17 NA NA NA NA NA NA 12669 XM_029355678.2 315 397 328 544 117 Q5VW36 0 Focadhesin Homo sapiens (Human) regulation of post-transcriptional gene silencing [GO:0060147] GO:0005925; GO:0016020; GO:0060147 12670 XM_029324874.2 1497 1029 594 874 850 Q5PQ53 1.37e-41 Peflin (PEF protein with a long N-terminal hydrophobic domain) (Penta-EF hand domain-containing protein 1) Xenopus laevis (African clawed frog) COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; positive regulation of protein monoubiquitination [GO:1902527] GO:0005509; GO:0005783; GO:0006888; GO:0014029; GO:0014032; GO:0030127; GO:0031463; GO:0048208; GO:1902527; GO:1990756 12671 XR_006395469.1 1253 2423 2362 2283 6216 NA NA NA NA NA NA 12672 XR_006394823.1 0 0 7 3 5 NA NA NA NA NA NA 12673 XM_044327394.1 3 5 0 0 11 NA NA NA NA NA NA 12674 XM_029350618.2 2 0 0 0 9 Q09575 9.58e-50 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 12675 XM_044318908.1 642 42 682 203 2069 NA NA NA NA NA NA 12676 XM_029339064.2 368 252 143 212 1300 Q9Z1G4 0 V-type proton ATPase 116 kDa subunit a 1 (V-ATPase 116 kDa subunit a 1) (Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit) (Vacuolar adenosine triphosphatase subunit Ac116) (Vacuolar proton pump subunit 1) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1) Mus musculus (Mouse) regulation of macroautophagy [GO:0016241]; synaptic vesicle lumen acidification [GO:0097401]; toxin transport [GO:1901998]; vacuolar acidification [GO:0007035] GO:0000220; GO:0005737; GO:0005794; GO:0005829; GO:0005886; GO:0007035; GO:0008021; GO:0016020; GO:0016241; GO:0016471; GO:0016607; GO:0030665; GO:0030672; GO:0042470; GO:0043229; GO:0043231; GO:0046961; GO:0048471; GO:0051117; GO:0097401; GO:1901998 12677 XM_044309626.1 30 29 45 109 189 NA NA NA NA NA NA 12678 XM_044323587.1 372 607 377 731 147 Q96DM1 4.91e-44 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 12679 XM_029345791.2 584 709 430 811 517 Q7A5L8 2e-35 L-threonine dehydratase catabolic TdcB (EC 4.3.1.19) (Threonine deaminase) Staphylococcus aureus (strain N315) L-threonine catabolic process to propionate [GO:0070689] GO:0000166; GO:0004794; GO:0030170; GO:0070689 12680 XM_044316767.1 283 207 100 136 64 NA NA NA NA NA NA 12681 XM_029332933.1 1544 1947 711 1852 1077 P92177 2.45e-96 14-3-3 protein epsilon (Suppressor of Ras1 3-9) Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; cytoplasmic sequestering of transcription factor [GO:0042994]; determination of adult lifespan [GO:0008340]; DNA damage checkpoint signaling [GO:0000077]; germarium-derived oocyte fate determination [GO:0007294]; microtubule sliding [GO:0051012]; negative regulation of neuron projection arborization [GO:0150013]; oocyte microtubule cytoskeleton polarization [GO:0008103]; pole cell migration [GO:0007280]; positive regulation of growth [GO:0045927]; positive regulation of hippo signaling [GO:0035332]; positive regulation of Ras protein signal transduction [GO:0046579]; R8 cell fate commitment [GO:0007460]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of mitotic nuclear division [GO:0007088]; response to UV [GO:0009411]; signal transduction [GO:0007165]; wing disc dorsal/ventral pattern formation [GO:0048190] GO:0000077; GO:0001223; GO:0005634; GO:0005654; GO:0005694; GO:0005737; GO:0005813; GO:0005829; GO:0005886; GO:0007088; GO:0007165; GO:0007280; GO:0007294; GO:0007346; GO:0007411; GO:0007460; GO:0008103; GO:0008340; GO:0009411; GO:0035332; GO:0040008; GO:0042994; GO:0045172; GO:0045927; GO:0046579; GO:0046982; GO:0048190; GO:0050815; GO:0051012; GO:0150013 12682 XR_003826541.2 3 0 0 0 11 NA NA NA NA NA NA 12683 XM_044313114.1 226 213 135 211 219 Q8R1F9 1.17e-65 Ribonuclease P protein subunit p40 (RNaseP protein p40) Mus musculus (Mouse) endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000447]; endonucleolytic cleavage involved in tRNA processing [GO:1905267]; tRNA 5'-leader removal [GO:0001682] GO:0000172; GO:0000447; GO:0001682; GO:0004526; GO:0005655; GO:0030681; GO:0033204; GO:1905267 12684 XM_029348865.2 0 0 0 0 14 P31646 0 Sodium- and chloride-dependent GABA transporter 2 (GAT-2) (Solute carrier family 6 member 13) Rattus norvegicus (Rat) amino acid import across plasma membrane [GO:0089718]; creatine transmembrane transport [GO:0015881]; gamma-aminobutyric acid import [GO:0051939]; monocarboxylic acid transport [GO:0015718]; neurotransmitter transport [GO:0006836]; nitrogen compound transport [GO:0071705]; positive regulation of necrotic cell death [GO:0010940]; sodium ion transmembrane transport [GO:0035725]; taurine transport [GO:0015734] GO:0005283; GO:0005308; GO:0005332; GO:0005368; GO:0005369; GO:0005886; GO:0006836; GO:0008028; GO:0010940; GO:0015171; GO:0015185; GO:0015718; GO:0015734; GO:0015881; GO:0016323; GO:0035725; GO:0042165; GO:0043005; GO:0051939; GO:0071705; GO:0089718 12685 XM_044323317.1 104 34 34 14 98 Q7RTR2 5.66e-32 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12686 XM_044313535.1 0 0 0 13 0 NA NA NA NA NA NA 12687 XM_044306928.1 335 201 0 346 478 Q8IVE3 0 Pleckstrin homology domain-containing family H member 2 Homo sapiens (Human) negative regulation of actin filament depolymerization [GO:0030835] GO:0003779; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0016604; GO:0030027; GO:0030835; GO:0030864 12688 XM_044327891.1 0 0 11 2 0 NA NA NA NA NA NA 12689 XM_044321885.1 755 400 757 751 765 Q6DV01 9.48e-83 Pre-mRNA-splicing factor syf2 Gekko japonicus (Schlegel's Japanese gecko) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0005634; GO:0071007 12690 XM_044306783.1 23 36 219 145 156 NA NA NA NA NA NA 12691 XM_029340194.2 189 0 174 202 177 P46735 0 Unconventional myosin-Ib (MIH-L) (Myosin I alpha) (MMI-alpha) (MMIa) Mus musculus (Mouse) actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; actin filament-based movement [GO:0030048]; post-Golgi vesicle-mediated transport [GO:0006892]; transferrin transport [GO:0033572]; vesicle transport along actin filament [GO:0030050] GO:0000146; GO:0003774; GO:0003779; GO:0005516; GO:0005524; GO:0005546; GO:0005547; GO:0005737; GO:0005769; GO:0005884; GO:0005886; GO:0005902; GO:0005903; GO:0006892; GO:0007015; GO:0010008; GO:0015629; GO:0016459; GO:0030048; GO:0030050; GO:0030175; GO:0031982; GO:0032588; GO:0033572; GO:0045177; GO:0048471; GO:0051015; GO:0051017; GO:0071944 12692 XM_044326713.1 199 172 87 242 123 B8VIW9 0 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 12693 XM_044322956.1 1040 1700 1051 1061 2720 D3YXS5 0 Kinesin-like protein KIF28 (Kinesin family member 28) (Kinesin-like protein 6) Mus musculus (Mouse) microtubule-based movement [GO:0007018]; mitochondrion organization [GO:0007005]; organelle transport along microtubule [GO:0072384] GO:0003777; GO:0005524; GO:0005871; GO:0005874; GO:0007005; GO:0007018; GO:0008017; GO:0016887; GO:0031966; GO:0072384 12694 XM_044325567.1 16 455 16 15 18 NA NA NA NA NA NA 12695 XM_029324897.2 2 1 13 1 21 B8VIU6 2.64e-59 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 12696 XM_044308258.1 1 16 15 59 25 Q9M2U3 1.05e-28 Protein ALP1-like (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) NA GO:0000118; GO:0004518; GO:0046872 12697 XR_006398040.1 29 61 169 11 14 NA NA NA NA NA NA 12698 XM_044328285.1 50 36 0 64 0 NA NA NA NA NA NA 12699 XM_029346923.2 632 361 286 542 541 Q7L5D6 2.55e-97 Golgi to ER traffic protein 4 homolog (Conserved edge-expressed protein) (Transmembrane domain recognition complex 35 kDa subunit) (TRC35) Homo sapiens (Human) cytoplasmic sequestering of protein [GO:0051220]; maintenance of unfolded protein involved in ERAD pathway [GO:1904378]; post-translational protein targeting to endoplasmic reticulum membrane [GO:0006620]; protein insertion into ER membrane [GO:0045048]; regulation of protein stability [GO:0031647]; tail-anchored membrane protein insertion into ER membrane [GO:0071816]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0005654; GO:0005694; GO:0005730; GO:0005737; GO:0005829; GO:0006511; GO:0006620; GO:0031647; GO:0045048; GO:0051087; GO:0051220; GO:0071816; GO:0071818; GO:1904378 12700 XM_044307252.1 179 411 336 260 706 Q99807 3.77e-55 5-demethoxyubiquinone hydroxylase, mitochondrial (DMQ hydroxylase) (EC 1.14.99.60) (Timing protein clk-1 homolog) (Ubiquinone biosynthesis monooxygenase COQ7) Homo sapiens (Human) determination of adult lifespan [GO:0008340]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression [GO:0010468]; regulation of reactive oxygen species metabolic process [GO:2000377]; ubiquinone biosynthetic process [GO:0006744] GO:0000122; GO:0003682; GO:0005634; GO:0005694; GO:0005739; GO:0005743; GO:0006744; GO:0008340; GO:0008682; GO:0010468; GO:0016709; GO:0031314; GO:0045944; GO:0046872; GO:0110142; GO:2000377 12701 XM_044319748.1 64 7 0 0 1 NA NA NA NA NA NA 12702 XM_044316631.1 156 6 68 284 165 NA NA NA NA NA NA 12703 XM_029347847.2 5 2 0 17 8 Q9CUX1 4.38e-25 52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (THAP domain-containing protein 0) (THAP domain-containing protein 12) Mus musculus (Mouse) NA GO:0003677; GO:0005634; GO:0046872; GO:0046983 12704 XM_029342813.2 12 3 21 62 43 NA NA NA NA NA NA 12705 XM_029344631.2 108 61 333 130 139 NA NA NA NA NA NA 12706 XM_044325261.1 1700 1361 874 1012 903 NA NA NA NA NA NA 12707 XM_044317645.1 0 0 0 0 40 Q66PG1 2.65e-41 Xylosyl- and glucuronyltransferase LARGE2s (EC 2.4.-.-) (Glycosyltransferase-like 1B) (LARGE xylosyl- and glucuronyltransferase 2) [Includes: Alpha-1,3-xylosyltransferase LARGE2 (EC 2.4.2.-); Beta-1,3-glucuronyltransferase LARGE2 (EC 2.4.1.-)] Danio rerio (Zebrafish) (Brachydanio rerio) protein glycosylation [GO:0006486]; protein O-linked mannosylation [GO:0035269] GO:0000139; GO:0005794; GO:0006486; GO:0015020; GO:0035269; GO:0042285; GO:0046872 12708 XM_044315644.1 0 128 0 15 15 Q27889 3.48e-70 Serine/threonine-protein phosphatase 2B catalytic subunit 2 (EC 3.1.3.16) (Calmodulin-dependent calcineurin A2 subunit) Drosophila melanogaster (Fruit fly) calcineurin-mediated signaling [GO:0097720]; female meiotic nuclear division [GO:0007143]; meiotic cell cycle [GO:0051321]; protein dephosphorylation [GO:0006470]; regulation of embryonic development [GO:0045995]; sleep [GO:0030431]; wing disc development [GO:0035220] GO:0004722; GO:0004723; GO:0005516; GO:0005737; GO:0005955; GO:0006470; GO:0007143; GO:0017018; GO:0030431; GO:0033192; GO:0035220; GO:0045995; GO:0046872; GO:0051321; GO:0097720 12709 XM_029327028.2 186 0 80 186 0 Q8TDB6 4.82e-27 E3 ubiquitin-protein ligase DTX3L (EC 2.3.2.27) (B-lymphoma- and BAL-associated protein) (Protein deltex-3-like) (RING-type E3 ubiquitin transferase DTX3L) (Rhysin-2) (Rhysin2) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; defense response to virus [GO:0051607]; DNA damage checkpoint signaling [GO:0000077]; double-strand break repair [GO:0006302]; endosome to lysosome transport [GO:0008333]; histone H2A ubiquitination [GO:0033522]; histone H2B ubiquitination [GO:0033523]; histone monoubiquitination [GO:0010390]; innate immune response [GO:0045087]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; Notch signaling pathway [GO:0007219]; positive regulation of chromatin binding [GO:0035563]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of receptor catabolic process [GO:2000646]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein transport [GO:0015031]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000077; GO:0002230; GO:0004842; GO:0004857; GO:0005634; GO:0005654; GO:0005737; GO:0005764; GO:0005765; GO:0005829; GO:0006302; GO:0006325; GO:0006511; GO:0006974; GO:0007219; GO:0008333; GO:0010390; GO:0015031; GO:0016567; GO:0019899; GO:0031901; GO:0032092; GO:0032991; GO:0033522; GO:0033523; GO:0035563; GO:0042393; GO:0044389; GO:0045087; GO:0045893; GO:0046872; GO:0051444; GO:0051607; GO:0051865; GO:0061630; GO:0070936; GO:0097677; GO:0140768; GO:1900182; GO:1902966; GO:2000646 12710 XM_029335840.2 1001 387 426 688 504 Q6NV34 8.27e-89 Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] (EC 1.3.1.124) (2,4-dienoyl-CoA reductase 2) Danio rerio (Zebrafish) (Brachydanio rerio) fatty acid catabolic process [GO:0009062]; fatty acid metabolic process [GO:0006631] GO:0005777; GO:0006631; GO:0008670; GO:0009062; GO:0016628 12711 XR_006393250.1 0 0 0 57 10 NA NA NA NA NA NA 12712 XM_029336213.2 4998 4719 3031 4521 2590 NA NA NA NA NA NA 12713 XM_029333499.2 3 147 96 275 126 Q1PSW8 5.97e-24 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (mLin41) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Mus musculus (Mouse) 3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to organic substance [GO:0071310]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA processing [GO:0035196]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; post-transcriptional regulation of gene expression [GO:0010608]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein metabolic process [GO:0051246]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0001843; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0010608; GO:0017148; GO:0021915; GO:0030371; GO:0035196; GO:0035198; GO:0035278; GO:0043161; GO:0051246; GO:0051865; GO:0060964; GO:0061158; GO:0061630; GO:0071310; GO:0072089; GO:2000177; GO:2000637 12714 XM_029336557.2 110 74 197 186 113 Q29496 3.99e-105 Cytochrome P450 3A24 (EC 1.14.14.1) (CYPIIIA24) Ovis aries (Sheep) NA GO:0004497; GO:0005506; GO:0005789; GO:0020037; GO:0070330 12715 XM_044312777.1 12 12 0 18 43 NA NA NA NA NA NA 12716 XM_044308218.1 300 110 111 151 72 P58307 3.85e-28 Orexin/Hypocretin receptor type 1 (Hypocretin receptor type 1) (Orexin receptor type 1) (Ox-1-R) (Ox1-R) (Ox1R) Mus musculus (Mouse) feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0004930; GO:0005886; GO:0007186; GO:0007218; GO:0007631; GO:0016499; GO:0017046; GO:0051480; GO:0070374 12717 XM_044317799.1 1854 884 698 1342 621 Q5QNQ6 5.66e-155 Oxysterol-binding protein 2 Mus musculus (Mouse) spermatid development [GO:0007286] GO:0005829; GO:0005886; GO:0007286; GO:0015248; GO:0015485; GO:0016020; GO:0032934; GO:0043231; GO:0097038; GO:0097440 12718 XM_044317799.1 1854 884 698 1342 621 Q5QNQ6 3.3e-76 Oxysterol-binding protein 2 Mus musculus (Mouse) spermatid development [GO:0007286] GO:0005829; GO:0005886; GO:0007286; GO:0015248; GO:0015485; GO:0016020; GO:0032934; GO:0043231; GO:0097038; GO:0097440 12719 XM_044328391.1 0 0 0 0 15 Q99315 3.75e-88 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 12720 XM_044313496.1 29 5 1 6 10 P07911 1.14e-50 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Homo sapiens (Human) antibacterial innate immune response [GO:0140367]; apoptotic signaling pathway [GO:0097190]; autophagy [GO:0006914]; cellular calcium ion homeostasis [GO:0006874]; cellular chloride ion homeostasis [GO:0030644]; cellular defense response [GO:0006968]; cellular phosphate ion homeostasis [GO:0030643]; cellular response to unfolded protein [GO:0034620]; cellular sodium ion homeostasis [GO:0006883]; chaperone-mediated protein folding [GO:0061077]; citric acid secretion [GO:0046720]; collecting duct development [GO:0072044]; connective tissue replacement [GO:0097709]; creatinine homeostasis [GO:0097273]; defense response to Gram-negative bacterium [GO:0050829]; endoplasmic reticulum organization [GO:0007029]; glomerular filtration [GO:0003094]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; juxtaglomerular apparatus development [GO:0072051]; leukocyte cell-cell adhesion [GO:0007159]; lipid metabolic process [GO:0006629]; metanephric ascending thin limb development [GO:0072218]; metanephric distal convoluted tubule development [GO:0072221]; metanephric thick ascending limb development [GO:0072233]; micturition [GO:0060073]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell population proliferation [GO:0008285]; neutrophil migration [GO:1990266]; organ or tissue specific immune response [GO:0002251]; peptidyl-threonine phosphorylation [GO:0018107]; potassium ion homeostasis [GO:0055075]; protein localization to vacuole [GO:0072665]; protein transport into plasma membrane raft [GO:0044861]; regulation of blood pressure [GO:0008217]; regulation of protein transport [GO:0051223]; regulation of urine volume [GO:0035809]; renal sodium ion absorption [GO:0070294]; renal urate salt excretion [GO:0097744]; renal water homeostasis [GO:0003091]; response to lipopolysaccharide [GO:0032496]; response to water deprivation [GO:0009414]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; ubiquitin-dependent ERAD pathway [GO:0030433]; urate transport [GO:0015747]; urea transmembrane transport [GO:0071918] GO:0000922; GO:0002251; GO:0003091; GO:0003094; GO:0005201; GO:0005509; GO:0005615; GO:0005783; GO:0005796; GO:0005929; GO:0006629; GO:0006874; GO:0006883; GO:0006914; GO:0006954; GO:0006968; GO:0007029; GO:0007157; GO:0007159; GO:0008217; GO:0008285; GO:0008380; GO:0009410; GO:0009414; GO:0009986; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0018107; GO:0019864; GO:0019898; GO:0030433; GO:0030643; GO:0030644; GO:0032496; GO:0033209; GO:0033555; GO:0034620; GO:0035809; GO:0044861; GO:0046720; GO:0050829; GO:0051223; GO:0055075; GO:0060073; GO:0060170; GO:0061077; GO:0070062; GO:0070294; GO:0071918; GO:0072044; GO:0072051; GO:0072218; GO:0072221; GO:0072233; GO:0072665; GO:0097190; GO:0097273; GO:0097709; GO:0097744; GO:0140367; GO:1990266 12721 XM_029346355.2 161 22 54 30 206 NA NA NA NA NA NA 12722 XM_044311364.1 77 40 19 79 19 P59046 2.74e-38 NACHT, LRR and PYD domains-containing protein 12 (Monarch-1) (PYRIN-containing APAF1-like protein 7) (Regulated by nitric oxide) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cellular response to cytokine stimulus [GO:0071345]; dendritic cell migration [GO:0036336]; ERK1 and ERK2 cascade [GO:0070371]; negative regulation of cytokine production [GO:0001818]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of signal transduction [GO:0009968]; negative regulation of Toll signaling pathway [GO:0045751]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of inflammatory response [GO:0050727]; regulation of interleukin-18 production [GO:0032661]; signal transduction [GO:0007165] GO:0001818; GO:0005524; GO:0005737; GO:0005829; GO:0006919; GO:0007165; GO:0008656; GO:0009968; GO:0031953; GO:0032088; GO:0032661; GO:0032692; GO:0032715; GO:0032731; GO:0036336; GO:0038061; GO:0043122; GO:0043124; GO:0043281; GO:0045345; GO:0045751; GO:0050727; GO:0050728; GO:0050729; GO:0070371; GO:0070373; GO:0071345; GO:1901223; GO:1901224 12723 XM_044310582.1 123 29 47 22 114 NA NA NA NA NA NA 12724 XM_029355349.2 4375 15 157 6806 3922 Q9QXS1 2.23e-52 Plectin (PCN) (PLTN) (Plectin-1) (Plectin-6) Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament organization [GO:0007015]; actomyosin contractile ring assembly actin filament organization [GO:2000689]; adherens junction organization [GO:0034332]; cardiac muscle cell development [GO:0055013]; cell morphogenesis [GO:0000902]; cell motility [GO:0048870]; cellular response to extracellular stimulus [GO:0031668]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrostatic pressure [GO:0071464]; cellular response to mechanical stimulus [GO:0071260]; establishment of skin barrier [GO:0061436]; fibroblast migration [GO:0010761]; gene expression [GO:0010467]; hemidesmosome assembly [GO:0031581]; intermediate filament cytoskeleton organization [GO:0045104]; intermediate filament organization [GO:0045109]; keratinocyte development [GO:0003334]; keratinocyte differentiation [GO:0030216]; leukocyte migration involved in immune response [GO:0002522]; mitochondrion morphogenesis [GO:0070584]; mitochondrion organization [GO:0007005]; multicellular organism growth [GO:0035264]; myelination in peripheral nervous system [GO:0022011]; myoblast differentiation [GO:0045445]; negative regulation of protein kinase activity [GO:0006469]; nucleus organization [GO:0006997]; peripheral nervous system myelin maintenance [GO:0032287]; protein localization [GO:0008104]; protein-containing complex organization [GO:0043933]; regulation of ATP citrate synthase activity [GO:2000983]; regulation of vascular permeability [GO:0043114]; respiratory electron transport chain [GO:0022904]; response to food [GO:0032094]; response to nutrient [GO:0007584]; sarcomere organization [GO:0045214]; skeletal muscle fiber development [GO:0048741]; skeletal muscle tissue development [GO:0007519]; skeletal myofibril assembly [GO:0014866]; skin development [GO:0043588]; T cell chemotaxis [GO:0010818]; tight junction organization [GO:0120193]; transmission of nerve impulse [GO:0019226]; wound healing [GO:0042060] GO:0000902; GO:0002162; GO:0002522; GO:0003334; GO:0003779; GO:0005198; GO:0005200; GO:0005737; GO:0005741; GO:0005829; GO:0005903; GO:0005925; GO:0006469; GO:0006997; GO:0007005; GO:0007015; GO:0007519; GO:0007584; GO:0008092; GO:0008104; GO:0008307; GO:0009925; GO:0010467; GO:0010761; GO:0010818; GO:0014866; GO:0016020; GO:0016324; GO:0016528; GO:0019226; GO:0022011; GO:0022904; GO:0030016; GO:0030018; GO:0030036; GO:0030056; GO:0030216; GO:0030424; GO:0030425; GO:0030506; GO:0031532; GO:0031581; GO:0031668; GO:0032094; GO:0032287; GO:0034332; GO:0035264; GO:0042060; GO:0042383; GO:0043114; GO:0043209; GO:0043292; GO:0043588; GO:0043621; GO:0043933; GO:0045104; GO:0045109; GO:0045111; GO:0045214; GO:0045445; GO:0047485; GO:0048471; GO:0048741; GO:0048870; GO:0051015; GO:0055013; GO:0061436; GO:0070584; GO:0071260; GO:0071464; GO:0071498; GO:0071944; GO:0120193; GO:2000689; GO:2000983 12725 XM_044325434.1 53 38 81 116 181 E1BB03 1.55e-143 DNA annealing helicase and endonuclease ZRANB3 (Annealing helicase 2) (AH2) (Zinc finger Ran-binding domain-containing protein 3) [Includes: DNA annealing helicase ZRANB3 (EC 3.6.4.-); Endonuclease ZRANB3 (EC 3.1.-.-)] Bos taurus (Bovine) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA rewinding [GO:0036292]; negative regulation of DNA recombination [GO:0045910]; replication fork processing [GO:0031297]; replication fork protection [GO:0048478]; response to UV [GO:0009411] GO:0004386; GO:0004520; GO:0005524; GO:0006281; GO:0006974; GO:0009411; GO:0031297; GO:0036292; GO:0036310; GO:0043596; GO:0045910; GO:0046872; GO:0048478; GO:0070530; GO:0140658 12726 XM_044325434.1 53 38 81 116 181 E1BB03 1.41e-46 DNA annealing helicase and endonuclease ZRANB3 (Annealing helicase 2) (AH2) (Zinc finger Ran-binding domain-containing protein 3) [Includes: DNA annealing helicase ZRANB3 (EC 3.6.4.-); Endonuclease ZRANB3 (EC 3.1.-.-)] Bos taurus (Bovine) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA rewinding [GO:0036292]; negative regulation of DNA recombination [GO:0045910]; replication fork processing [GO:0031297]; replication fork protection [GO:0048478]; response to UV [GO:0009411] GO:0004386; GO:0004520; GO:0005524; GO:0006281; GO:0006974; GO:0009411; GO:0031297; GO:0036292; GO:0036310; GO:0043596; GO:0045910; GO:0046872; GO:0048478; GO:0070530; GO:0140658 12727 XM_029333274.2 4449 3151 1714 3897 4325 O57478 0 Ferrochelatase, mitochondrial (EC 4.98.1.1) (Heme synthase) (Protoheme ferro-lyase) Xenopus laevis (African clawed frog) heme biosynthetic process [GO:0006783] GO:0004325; GO:0005743; GO:0006783; GO:0046872; GO:0051537 12728 XM_044311081.1 20 4 0 20 24 NA NA NA NA NA NA 12729 XM_029350739.2 16 20 5 26 8 NA NA NA NA NA NA 12730 XM_044324366.1 17 24 38 50 73 NA NA NA NA NA NA 12731 XM_044321231.1 633 553 403 526 634 O15067 0 Phosphoribosylformylglycinamidine synthase (FGAM synthase) (FGAMS) (EC 6.3.5.3) (Formylglycinamide ribonucleotide amidotransferase) (FGAR amidotransferase) (FGAR-AT) (Formylglycinamide ribotide amidotransferase) (Phosphoribosylformylglycineamide amidotransferase) Homo sapiens (Human) 'de novo' AMP biosynthetic process [GO:0044208]; 'de novo' IMP biosynthetic process [GO:0006189]; 'de novo' XMP biosynthetic process [GO:0097294]; anterior head development [GO:0097065]; glutamine metabolic process [GO:0006541]; GMP biosynthetic process [GO:0006177]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to xenobiotic stimulus [GO:0009410] GO:0004642; GO:0005524; GO:0005829; GO:0006177; GO:0006189; GO:0006541; GO:0009168; GO:0009410; GO:0044208; GO:0046872; GO:0070062; GO:0097065; GO:0097294 12732 XM_044315855.1 19 15 11 15 0 NA NA NA NA NA NA 12733 XM_029337258.2 239 528 320 292 391 A7M7B9 3.46e-101 Endonuclease III-like protein 1 (EC 3.2.2.-) (EC 4.2.99.18) (Bifunctional DNA N-glycosylase/DNA-(apurinic or apyrimidinic site) lyase) (DNA glycosylase/AP lyase) Gallus gallus (Chicken) base-excision repair, AP site formation [GO:0006285]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296] GO:0000703; GO:0003677; GO:0003906; GO:0005634; GO:0005739; GO:0006285; GO:0006296; GO:0046872; GO:0051539; GO:0140078 12734 XM_044328820.1 6 4 8 0 4 NA NA NA NA NA NA 12735 XM_029333482.2 110 10 231 294 115 NA NA NA NA NA NA 12736 XM_044315407.1 13 16 17 22 25 NA NA NA NA NA NA 12737 XM_044322191.1 510 116 592 78 1610 O46560 1.02e-101 Pyridoxal kinase (EC 2.7.1.35) (Pyridoxine kinase) Sus scrofa (Pig) phosphorylation [GO:0016310]; pyridoxal 5'-phosphate salvage [GO:0009443] GO:0005524; GO:0005829; GO:0008478; GO:0009443; GO:0016310; GO:0046872 12738 XM_044324661.1 14 26 52 57 39 NA NA NA NA NA NA 12739 XR_003822877.2 14 5 0 4 4 NA NA NA NA NA NA 12740 XM_044313802.1 69 77 32 14 35 B9IUR6 4.68e-53 2-aminoethylphosphonate--pyruvate transaminase (EC 2.6.1.37) (2-aminoethylphosphonate aminotransferase) (AEP transaminase) (AEPT) Bacillus cereus (strain Q1) organic phosphonate catabolic process [GO:0019700] GO:0019700; GO:0047304 12741 XM_044319476.1 115 42 82 67 150 P0CI65 1.95e-42 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 12742 XM_044319476.1 115 42 82 67 150 P0CI65 2.23e-39 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 12743 XM_044319476.1 115 42 82 67 150 P0CI65 1.81e-36 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 12744 XM_029328513.2 22 0 2 2 4 Q2QEI3 4.82e-50 Type I iodothyronine deiodinase (EC 1.21.99.4) (5DI) (DIOI) (Type 1 DI) (Type-I 5'-deiodinase) Xenopus laevis (African clawed frog) hormone biosynthetic process [GO:0042446] GO:0004800; GO:0005789; GO:0042446 12745 XM_029339785.2 1424 1673 914 984 851 O95295 2.38e-36 SNARE-associated protein Snapin (Biogenesis of lysosome-related organelles complex 1 subunit 7) (BLOC-1 subunit 7) (Synaptosomal-associated protein 25-binding protein) (SNAP-associated protein) Homo sapiens (Human) anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; autophagosome maturation [GO:0097352]; endosome to lysosome transport [GO:0008333]; intracellular protein transport [GO:0006886]; late endosome to lysosome transport [GO:1902774]; lysosomal lumen acidification [GO:0007042]; lysosome localization [GO:0032418]; lysosome organization [GO:0007040]; melanosome organization [GO:0032438]; negative regulation of neuron projection development [GO:0010977]; neuron cellular homeostasis [GO:0070050]; neuron projection development [GO:0031175]; neurotransmitter secretion [GO:0007269]; organelle transport along microtubule [GO:0072384]; positive regulation of late endosome to lysosome transport [GO:1902824]; protein maturation [GO:0051604]; protein-containing complex localization [GO:0031503]; regulation of endosome size [GO:0051036]; regulation of lysosome size [GO:0062196]; regulation of protein binding [GO:0043393]; regulation of synaptic vesicle exocytosis [GO:2000300]; retrograde axonal transport [GO:0008090]; synaptic vesicle exocytosis [GO:0016079]; synaptic vesicle fusion to presynaptic active zone membrane [GO:0031629]; synaptic vesicle maturation [GO:0016188]; synaptic vesicle transport [GO:0048489]; terminal button organization [GO:0072553] GO:0000139; GO:0000149; GO:0001669; GO:0002177; GO:0005829; GO:0006886; GO:0007040; GO:0007042; GO:0007269; GO:0008021; GO:0008089; GO:0008090; GO:0008333; GO:0010977; GO:0016079; GO:0016188; GO:0030141; GO:0030672; GO:0031083; GO:0031175; GO:0031503; GO:0031629; GO:0032418; GO:0032438; GO:0043393; GO:0045202; GO:0048471; GO:0048489; GO:0048490; GO:0051036; GO:0051604; GO:0062196; GO:0070050; GO:0072384; GO:0072553; GO:0097352; GO:0098574; GO:0099078; GO:1902774; GO:1902824; GO:1904115; GO:2000300 12746 XR_006393474.1 37 5 0 20 20 P49013 4.34e-55 Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374 12747 XR_006393474.1 37 5 0 20 20 P49013 8.28e-54 Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374 12748 XR_006393474.1 37 5 0 20 20 P49013 2.94e-49 Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374 12749 XR_006393474.1 37 5 0 20 20 P49013 5.28e-39 Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374 12750 XR_006393474.1 37 5 0 20 20 P49013 2.45e-37 Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374 12751 XR_006393474.1 37 5 0 20 20 P49013 3.6e-27 Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374 12752 XM_044327973.1 26 0 0 0 0 NA NA NA NA NA NA 12753 XR_006395071.1 80 52 28 133 86 Q8BID8 1.69e-25 F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14) Mus musculus (Mouse) SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004842; GO:0005737; GO:0006511; GO:0019005; GO:0031146 12754 XM_044316566.1 0 0 7 0 0 NA NA NA NA NA NA 12755 XM_029334530.2 1885 378 563 1009 1094 E1C1L6 6.75e-107 Ectonucleoside triphosphate diphosphohydrolase 5 (NTPDase 5) (EC 3.6.1.6) (Guanosine-diphosphatase ENTPD5) (GDPase ENTPD5) (Uridine-diphosphatase ENTPD5) (UDPase ENTPD5) Gallus gallus (Chicken) 'de novo' post-translational protein folding [GO:0051084]; nucleoside diphosphate catabolic process [GO:0009134]; protein N-linked glycosylation [GO:0006487]; UDP catabolic process [GO:0006256]; UDP-glucose metabolic process [GO:0006011] GO:0004382; GO:0005576; GO:0005783; GO:0006011; GO:0006256; GO:0006487; GO:0009134; GO:0016020; GO:0017110; GO:0036384; GO:0043262; GO:0045134; GO:0051084; GO:1990003 12756 XR_006394711.1 17 101 27 47 26 NA NA NA NA NA NA 12757 XM_044320850.1 783 349 274 842 242 Q6DFH9 3.08e-103 60S ribosome subunit biogenesis protein NIP7 homolog Xenopus laevis (African clawed frog) ribosome assembly [GO:0042255] GO:0003723; GO:0005654; GO:0005730; GO:0042255 12758 XM_029338367.2 4 10 0 11 5 NA NA NA NA NA NA 12759 XM_044326703.1 862 147 132 915 477 NA NA NA NA NA NA 12760 XM_029329165.2 809 477 318 545 519 Q9Y6K8 2.88e-114 Adenylate kinase isoenzyme 5 (AK 5) (EC 2.7.4.3) (EC 2.7.4.6) (ATP-AMP transphosphorylase 5) Homo sapiens (Human) ADP biosynthetic process [GO:0006172]; ATP metabolic process [GO:0046034]; dADP biosynthetic process [GO:0006173]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; pyrimidine ribonucleotide biosynthetic process [GO:0009220] GO:0004017; GO:0004550; GO:0005524; GO:0005737; GO:0005829; GO:0006165; GO:0006172; GO:0006173; GO:0009142; GO:0009220; GO:0034451; GO:0046034 12761 XM_029329165.2 809 477 318 545 519 Q9Y6K8 3.52e-54 Adenylate kinase isoenzyme 5 (AK 5) (EC 2.7.4.3) (EC 2.7.4.6) (ATP-AMP transphosphorylase 5) Homo sapiens (Human) ADP biosynthetic process [GO:0006172]; ATP metabolic process [GO:0046034]; dADP biosynthetic process [GO:0006173]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; pyrimidine ribonucleotide biosynthetic process [GO:0009220] GO:0004017; GO:0004550; GO:0005524; GO:0005737; GO:0005829; GO:0006165; GO:0006172; GO:0006173; GO:0009142; GO:0009220; GO:0034451; GO:0046034 12762 XM_029329165.2 809 477 318 545 519 Q9Y6K8 4.58e-52 Adenylate kinase isoenzyme 5 (AK 5) (EC 2.7.4.3) (EC 2.7.4.6) (ATP-AMP transphosphorylase 5) Homo sapiens (Human) ADP biosynthetic process [GO:0006172]; ATP metabolic process [GO:0046034]; dADP biosynthetic process [GO:0006173]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; pyrimidine ribonucleotide biosynthetic process [GO:0009220] GO:0004017; GO:0004550; GO:0005524; GO:0005737; GO:0005829; GO:0006165; GO:0006172; GO:0006173; GO:0009142; GO:0009220; GO:0034451; GO:0046034 12763 XR_006393194.1 287 216 507 458 1013 NA NA NA NA NA NA 12764 XR_006394004.1 39 14 7 40 4 NA NA NA NA NA NA 12765 XM_044328259.1 0 141 0 52 32 D3ZKU7 3.46e-33 Biogenesis of lysosome-related organelles complex 1 subunit 1 (BLOC-1 subunit 1) Rattus norvegicus (Rat) aerobic respiration [GO:0009060]; anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; endosomal transport [GO:0016197]; lysosome localization [GO:0032418]; neuron projection development [GO:0031175]; peptidyl-lysine acetylation [GO:0018394] GO:0005758; GO:0005759; GO:0005765; GO:0005769; GO:0005829; GO:0008089; GO:0009060; GO:0016197; GO:0018394; GO:0031083; GO:0031175; GO:0032418; GO:0048490; GO:0099078; GO:1904115 12766 XM_044319486.1 628 605 1340 1551 2672 Q7Z494 1.22e-46 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 12767 XM_044319486.1 628 605 1340 1551 2672 Q7Z494 1.95e-43 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 12768 XM_044319486.1 628 605 1340 1551 2672 Q7Z494 7.25e-42 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 12769 XM_044319486.1 628 605 1340 1551 2672 Q7Z494 3.96e-38 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 12770 XM_029328402.2 308 0 125 190 135 Q0VFE3 1.67e-76 Post-GPI attachment to proteins factor 3 (PER1-like domain-containing protein 1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) GPI anchor biosynthetic process [GO:0006506]; GPI anchor metabolic process [GO:0006505] GO:0000139; GO:0005789; GO:0006505; GO:0006506; GO:0016788 12771 XM_029353447.2 0 5 0 10 4 NA NA NA NA NA NA 12772 XM_029341173.2 0 28 0 0 0 NA NA NA NA NA NA 12773 XM_029337706.2 0 22 8 8 10 Q9GRC0 8.73e-74 Serine/threonine-protein kinase mos (EC 2.7.11.1) (Oocyte maturation factor mos) Patiria pectinifera (Starfish) (Asterina pectinifera) female gamete generation [GO:0007292]; female meiosis II [GO:0007147]; negative regulation of mitotic cell cycle [GO:0045930]; protein phosphorylation [GO:0006468] GO:0004709; GO:0005524; GO:0006468; GO:0007147; GO:0007292; GO:0045930; GO:0106310 12774 XM_044316654.1 167 85 173 85 120 P11617 5.18e-22 Adenosine receptor A2a Canis lupus familiaris (Dog) (Canis familiaris) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; apoptotic signaling pathway [GO:0097190]; eating behavior [GO:0042755]; G protein-coupled adenosine receptor signaling pathway [GO:0001973]; G protein-coupled receptor signaling pathway [GO:0007186]; inhibitory postsynaptic potential [GO:0060080]; locomotory behavior [GO:0007626]; negative regulation of alpha-beta T cell activation [GO:0046636]; negative regulation of inflammatory response [GO:0050728]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; response to amphetamine [GO:0001975]; response to inorganic substance [GO:0010035]; response to purine-containing compound [GO:0014074]; synaptic transmission, dopaminergic [GO:0001963] GO:0001609; GO:0001963; GO:0001973; GO:0001975; GO:0004930; GO:0005886; GO:0007186; GO:0007189; GO:0007626; GO:0008289; GO:0010035; GO:0014074; GO:0019899; GO:0032230; GO:0042755; GO:0042802; GO:0046636; GO:0050728; GO:0060080; GO:0097190; GO:0098794; GO:2001235 12775 XM_029358394.2 25 102 77 0 0 NA NA NA NA NA NA 12776 XR_006395689.1 86 168 104 85 127 NA NA NA NA NA NA 12777 XM_044317334.1 1071 1779 367 1784 627 NA NA NA NA NA NA 12778 XM_044324183.1 0 0 0 0 17 NA NA NA NA NA NA 12779 XM_029355689.2 104 35 64 280 217 Q0IH87 4.67e-56 Paired box protein Pax-3-B (xPax3-B) (Paired-domain transcription factor Pax3-B) Xenopus laevis (African clawed frog) fibroblast growth factor receptor signaling pathway [GO:0008543]; hatching gland development [GO:0048785]; nervous system development [GO:0007399]; neural crest cell fate commitment [GO:0014034]; neural crest formation [GO:0014029]; positive regulation of DNA-templated transcription [GO:0045893]; Wnt signaling pathway [GO:0016055] GO:0000981; GO:0003677; GO:0005634; GO:0007399; GO:0008543; GO:0014029; GO:0014034; GO:0016055; GO:0045893; GO:0048785 12780 XR_003822750.2 146 84 79 106 151 NA NA NA NA NA NA 12781 XM_029335377.2 10 17 6 21 0 NA NA NA NA NA NA 12782 XM_044312911.1 46 33 38 25 30 NA NA NA NA NA NA 12783 XM_044321760.1 123 1 0 72 106 Q91740 1.26e-21 Fibronectin (FN) Xenopus laevis (African clawed frog) acute-phase response [GO:0006953]; cell adhesion [GO:0007155]; regulation of cell shape [GO:0008360] GO:0005576; GO:0006953; GO:0007155; GO:0008201; GO:0008360 12784 XM_029344005.2 1502 1918 1170 1136 1673 Q8NFH4 1.01e-92 Nucleoporin Nup37 (p37) (Nup107-160 subcomplex subunit Nup37) Homo sapiens (Human) cell division [GO:0051301]; chromosome segregation [GO:0007059]; mRNA transport [GO:0051028]; nucleocytoplasmic transport [GO:0006913]; protein transport [GO:0015031] GO:0000776; GO:0005634; GO:0005635; GO:0005643; GO:0005654; GO:0005829; GO:0006913; GO:0007059; GO:0015031; GO:0031080; GO:0051028; GO:0051301 12785 XM_044314589.1 52 48 44 66 229 NA NA NA NA NA NA 12786 XM_029330225.2 135 270 190 166 191 Q5EB68 2.37e-79 Adenylate kinase isoenzyme 6 (AK6) (EC 2.7.4.3) (Coilin-interacting nuclear ATPase protein) (Dual activity adenylate kinase/ATPase) (AK/ATPase) Rattus norvegicus (Rat) phosphorylation [GO:0016310] GO:0004017; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0015030; GO:0016310; GO:0016887 12787 XR_006392787.1 19 0 2 0 0 NA NA NA NA NA NA 12788 XM_029337650.2 44 0 0 41 205 E7F5E1 6.93e-97 Centrosomal protein of 162 kDa (Cep162) Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; heart looping [GO:0001947] GO:0001947; GO:0005813; GO:0005814; GO:0005879; GO:0060271 12789 XM_029341881.2 3787 1153 575 1571 1370 A0A0G2K1Q8 0 Phospholipid-transporting ATPase ABCA3 (EC 7.6.2.1) (ATP-binding cassette sub-family A member 3) (Xenobiotic-transporting ATPase ABCA3) (EC 7.6.2.2) [Cleaved into: 150 Kda mature form] Rattus norvegicus (Rat) lipid transport [GO:0006869]; lung development [GO:0030324]; organelle assembly [GO:0070925]; phosphatidylcholine metabolic process [GO:0046470]; phosphatidylglycerol metabolic process [GO:0046471]; phospholipid homeostasis [GO:0055091]; phospholipid transport [GO:0015914]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of phospholipid efflux [GO:1902995]; positive regulation of phospholipid transport [GO:2001140]; positive regulation of protein homooligomerization [GO:0032464]; regulation of lipid biosynthetic process [GO:0046890]; regulation of lipid transport [GO:0032368]; regulation of phosphatidylcholine metabolic process [GO:0150172]; response to glucocorticoid [GO:0051384]; surfactant homeostasis [GO:0043129]; xenobiotic export from cell [GO:0046618]; xenobiotic transmembrane transport [GO:0006855]; xenobiotic transport [GO:0042908] GO:0005319; GO:0005524; GO:0005765; GO:0005770; GO:0005886; GO:0006855; GO:0006869; GO:0008559; GO:0010875; GO:0015914; GO:0016887; GO:0030324; GO:0030659; GO:0032368; GO:0032464; GO:0032585; GO:0042599; GO:0042626; GO:0042908; GO:0043129; GO:0043231; GO:0046470; GO:0046471; GO:0046618; GO:0046890; GO:0051384; GO:0055091; GO:0070925; GO:0097208; GO:0097232; GO:0097233; GO:0120019; GO:0140345; GO:0150172; GO:1902995; GO:2001140 12790 XM_029341881.2 3787 1153 575 1571 1370 A0A0G2K1Q8 4.27e-120 Phospholipid-transporting ATPase ABCA3 (EC 7.6.2.1) (ATP-binding cassette sub-family A member 3) (Xenobiotic-transporting ATPase ABCA3) (EC 7.6.2.2) [Cleaved into: 150 Kda mature form] Rattus norvegicus (Rat) lipid transport [GO:0006869]; lung development [GO:0030324]; organelle assembly [GO:0070925]; phosphatidylcholine metabolic process [GO:0046470]; phosphatidylglycerol metabolic process [GO:0046471]; phospholipid homeostasis [GO:0055091]; phospholipid transport [GO:0015914]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of phospholipid efflux [GO:1902995]; positive regulation of phospholipid transport [GO:2001140]; positive regulation of protein homooligomerization [GO:0032464]; regulation of lipid biosynthetic process [GO:0046890]; regulation of lipid transport [GO:0032368]; regulation of phosphatidylcholine metabolic process [GO:0150172]; response to glucocorticoid [GO:0051384]; surfactant homeostasis [GO:0043129]; xenobiotic export from cell [GO:0046618]; xenobiotic transmembrane transport [GO:0006855]; xenobiotic transport [GO:0042908] GO:0005319; GO:0005524; GO:0005765; GO:0005770; GO:0005886; GO:0006855; GO:0006869; GO:0008559; GO:0010875; GO:0015914; GO:0016887; GO:0030324; GO:0030659; GO:0032368; GO:0032464; GO:0032585; GO:0042599; GO:0042626; GO:0042908; GO:0043129; GO:0043231; GO:0046470; GO:0046471; GO:0046618; GO:0046890; GO:0051384; GO:0055091; GO:0070925; GO:0097208; GO:0097232; GO:0097233; GO:0120019; GO:0140345; GO:0150172; GO:1902995; GO:2001140 12791 XM_029341881.2 3787 1153 575 1571 1370 A0A0G2K1Q8 2.26e-48 Phospholipid-transporting ATPase ABCA3 (EC 7.6.2.1) (ATP-binding cassette sub-family A member 3) (Xenobiotic-transporting ATPase ABCA3) (EC 7.6.2.2) [Cleaved into: 150 Kda mature form] Rattus norvegicus (Rat) lipid transport [GO:0006869]; lung development [GO:0030324]; organelle assembly [GO:0070925]; phosphatidylcholine metabolic process [GO:0046470]; phosphatidylglycerol metabolic process [GO:0046471]; phospholipid homeostasis [GO:0055091]; phospholipid transport [GO:0015914]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of phospholipid efflux [GO:1902995]; positive regulation of phospholipid transport [GO:2001140]; positive regulation of protein homooligomerization [GO:0032464]; regulation of lipid biosynthetic process [GO:0046890]; regulation of lipid transport [GO:0032368]; regulation of phosphatidylcholine metabolic process [GO:0150172]; response to glucocorticoid [GO:0051384]; surfactant homeostasis [GO:0043129]; xenobiotic export from cell [GO:0046618]; xenobiotic transmembrane transport [GO:0006855]; xenobiotic transport [GO:0042908] GO:0005319; GO:0005524; GO:0005765; GO:0005770; GO:0005886; GO:0006855; GO:0006869; GO:0008559; GO:0010875; GO:0015914; GO:0016887; GO:0030324; GO:0030659; GO:0032368; GO:0032464; GO:0032585; GO:0042599; GO:0042626; GO:0042908; GO:0043129; GO:0043231; GO:0046470; GO:0046471; GO:0046618; GO:0046890; GO:0051384; GO:0055091; GO:0070925; GO:0097208; GO:0097232; GO:0097233; GO:0120019; GO:0140345; GO:0150172; GO:1902995; GO:2001140 12792 XM_029341881.2 3787 1153 575 1571 1370 A0A0G2K1Q8 2.8e-43 Phospholipid-transporting ATPase ABCA3 (EC 7.6.2.1) (ATP-binding cassette sub-family A member 3) (Xenobiotic-transporting ATPase ABCA3) (EC 7.6.2.2) [Cleaved into: 150 Kda mature form] Rattus norvegicus (Rat) lipid transport [GO:0006869]; lung development [GO:0030324]; organelle assembly [GO:0070925]; phosphatidylcholine metabolic process [GO:0046470]; phosphatidylglycerol metabolic process [GO:0046471]; phospholipid homeostasis [GO:0055091]; phospholipid transport [GO:0015914]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of phospholipid efflux [GO:1902995]; positive regulation of phospholipid transport [GO:2001140]; positive regulation of protein homooligomerization [GO:0032464]; regulation of lipid biosynthetic process [GO:0046890]; regulation of lipid transport [GO:0032368]; regulation of phosphatidylcholine metabolic process [GO:0150172]; response to glucocorticoid [GO:0051384]; surfactant homeostasis [GO:0043129]; xenobiotic export from cell [GO:0046618]; xenobiotic transmembrane transport [GO:0006855]; xenobiotic transport [GO:0042908] GO:0005319; GO:0005524; GO:0005765; GO:0005770; GO:0005886; GO:0006855; GO:0006869; GO:0008559; GO:0010875; GO:0015914; GO:0016887; GO:0030324; GO:0030659; GO:0032368; GO:0032464; GO:0032585; GO:0042599; GO:0042626; GO:0042908; GO:0043129; GO:0043231; GO:0046470; GO:0046471; GO:0046618; GO:0046890; GO:0051384; GO:0055091; GO:0070925; GO:0097208; GO:0097232; GO:0097233; GO:0120019; GO:0140345; GO:0150172; GO:1902995; GO:2001140 12793 XM_029342500.2 321 176 198 264 199 NA NA NA NA NA NA 12794 XM_044317966.1 191 2 26 0 0 NA NA NA NA NA NA 12795 XM_029337125.2 101 235 148 83 112 NA NA NA NA NA NA 12796 XM_029323834.2 2415 1746 1312 1672 1891 D3ZWZ9 2.84e-125 Protein GPR107 Rattus norvegicus (Rat) clathrin-dependent endocytosis [GO:0072583] GO:0005654; GO:0005769; GO:0005794; GO:0005886; GO:0016020; GO:0030136; GO:0032050; GO:0072583 12797 XR_006395081.1 67 34 108 35 143 NA NA NA NA NA NA 12798 XM_029337121.2 20 0 0 18 0 Q5F2F2 1.35e-61 Protein ABHD15 (Alpha/beta hydrolase domain-containing protein 15) (Abhydrolase domain-containing protein 15) Mus musculus (Mouse) cellular lipid metabolic process [GO:0044255] GO:0005576; GO:0034338; GO:0044255; GO:0047372 12799 XM_044307167.1 75 68 134 98 98 Q5RA17 5.8e-45 Ribosomal RNA-processing protein 7 homolog A (Gastric cancer antigen Zg14 homolog) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cilium disassembly [GO:0061523]; ribosome biogenesis [GO:0042254]; rRNA processing [GO:0006364] GO:0003723; GO:0005730; GO:0005737; GO:0005813; GO:0005929; GO:0006364; GO:0042254; GO:0061523 12800 XM_029347702.2 74 12 0 12 33 Q9CPR1 4.72e-34 RWD domain-containing protein 4 Mus musculus (Mouse) NA NA 12801 XM_029343136.2 793 471 459 523 566 Q9CZB9 8.4e-30 Transmembrane protein 128 Mus musculus (Mouse) NA GO:0016020 12802 XM_029323937.2 851 534 374 810 821 Q3UCV8 1.3e-53 Ubiquitin thioesterase otulin (EC 3.4.19.12) (Deubiquitinating enzyme otulin) (OTU domain-containing deubiquitinase with linear linkage specificity) (Ubiquitin thioesterase Gumby) Mus musculus (Mouse) innate immune response [GO:0045087]; negative regulation of inflammatory response [GO:0050728]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; protein linear deubiquitination [GO:1990108]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; sprouting angiogenesis [GO:0002040]; Wnt signaling pathway [GO:0016055] GO:0002040; GO:0004843; GO:0005737; GO:0008234; GO:0010803; GO:0016055; GO:0032088; GO:0045087; GO:0050728; GO:0060828; GO:0070431; GO:1990108 12803 XM_044314495.1 24 11 12 22 98 P46023 1.32e-104 G-protein coupled receptor GRL101 Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004930; GO:0005886 12804 XM_029339111.2 458 531 550 281 1053 Q3TZ87 1.19e-22 E3 ubiquitin-protein ligase MARCHF9 (EC 2.3.2.27) (Membrane-associated RING finger protein 9) (Membrane-associated RING-CH protein IX) (MARCH-IX) (RING-type E3 ubiquitin transferase MARCHF9) Mus musculus (Mouse) NA GO:0000139; GO:0004842; GO:0005765; GO:0005795; GO:0005802; GO:0008270 12805 XM_029344880.2 809 613 269 747 142 Q8R5F3 1.45e-59 ADP-ribose glycohydrolase OARD1 (O-acetyl-ADP-ribose deacetylase 1) (EC 3.5.1.-) (Terminal ADP-ribose protein glycohydrolase 1) ([Protein ADP-ribosylglutamate] hydrolase OARD1) (EC 3.2.2.-) Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; peptidyl-glutamate ADP-deribosylation [GO:0140291]; protein de-ADP-ribosylation [GO:0051725]; purine nucleoside metabolic process [GO:0042278] GO:0001883; GO:0005654; GO:0005730; GO:0006974; GO:0042278; GO:0051725; GO:0061463; GO:0090734; GO:0140291; GO:0140293 12806 XM_044314128.1 75 17 13 124 12 NA NA NA NA NA NA 12807 XM_044321525.1 110 5 22 0 56 NA NA NA NA NA NA 12808 XM_029323613.2 383 337 225 365 433 B2GUY0 0 Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC 3.2.1.113) (ER alpha-1,2-mannosidase) (ER mannosidase 1) (ERMan1) (Mannosidase alpha class 1B member 1) Rattus norvegicus (Rat) carbohydrate metabolic process [GO:0005975]; endoplasmic reticulum mannose trimming [GO:1904380]; mannose trimming involved in glycoprotein ERAD pathway [GO:1904382]; N-glycan processing [GO:0006491]; protein alpha-1,2-demannosylation [GO:0036508]; protein glycosylation [GO:0006486]; trimming of terminal mannose on B branch [GO:0036509]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0004571; GO:0005509; GO:0005783; GO:0005789; GO:0005975; GO:0006486; GO:0006491; GO:0016020; GO:0030433; GO:0031410; GO:0036508; GO:0036509; GO:0044322; GO:1904380; GO:1904382 12809 XR_003827328.2 234 247 144 287 179 NA NA NA NA NA NA 12810 XM_029338899.2 38 370 282 424 697 Q7XJJ7 1.43e-93 Fatty acid amide hydrolase (AtFAAH) (EC 3.5.1.99) (N-acylethanolamine amidohydrolase) Arabidopsis thaliana (Mouse-ear cress) defense response to bacterium [GO:0042742]; lipid catabolic process [GO:0016042]; N-acylethanolamine metabolic process [GO:0070291] GO:0000325; GO:0005783; GO:0005789; GO:0005794; GO:0005886; GO:0009536; GO:0016020; GO:0016042; GO:0017064; GO:0042742; GO:0047412; GO:0070291 12811 XR_006394161.1 6 33 0 2 26 NA NA NA NA NA NA 12812 XM_029343430.2 4 0 4 0 23 NA NA NA NA NA NA 12813 XM_044322706.1 46 45 35 36 41 Q80XJ3 1.83e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 12814 XM_044322706.1 46 45 35 36 41 Q80XJ3 1.81e-71 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 12815 XM_044322706.1 46 45 35 36 41 Q80XJ3 3.46e-69 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 12816 XM_044322706.1 46 45 35 36 41 Q80XJ3 5.52e-68 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 12817 XM_044322706.1 46 45 35 36 41 Q80XJ3 4.28e-65 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 12818 XM_044322706.1 46 45 35 36 41 Q80XJ3 5.05e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 12819 XM_044322706.1 46 45 35 36 41 Q80XJ3 4.59e-58 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 12820 XM_044322706.1 46 45 35 36 41 Q80XJ3 3.04e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 12821 XM_044322706.1 46 45 35 36 41 Q80XJ3 3.59e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 12822 XM_029358702.2 234 149 189 146 258 Q3UJP5 1.82e-45 Cilia- and flagella-associated protein 418 Mus musculus (Mouse) photoreceptor cell morphogenesis [GO:0008594] GO:0001917; GO:0005737; GO:0005829; GO:0005886; GO:0008594; GO:0030054; GO:0097546 12823 XM_029337488.2 0 0 0 0 62 O09118 0 Netrin-1 Mus musculus (Mouse) animal organ morphogenesis [GO:0009887]; anterior/posterior axon guidance [GO:0033564]; apoptotic process [GO:0006915]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; B cell mediated immunity [GO:0019724]; B cell proliferation [GO:0042100]; Cdc42 protein signal transduction [GO:0032488]; cell population proliferation [GO:0008283]; cell-cell adhesion [GO:0098609]; chemorepulsion of axon [GO:0061643]; dendrite development [GO:0016358]; glial cell proliferation [GO:0014009]; inner ear morphogenesis [GO:0042472]; mammary gland development [GO:0030879]; mammary gland duct morphogenesis [GO:0060603]; motor neuron axon guidance [GO:0008045]; motor neuron migration [GO:0097475]; negative regulation of axon extension [GO:0030517]; neuron migration [GO:0001764]; nuclear migration [GO:0007097]; positive regulation of axon extension [GO:0045773]; positive regulation of cell motility [GO:2000147]; positive regulation of glial cell proliferation [GO:0060252]; Ras protein signal transduction [GO:0007265]; regulation of cell migration [GO:0030334]; regulation of glial cell migration [GO:1903975]; regulation of synapse assembly [GO:0051963]; substrate-dependent cell migration, cell extension [GO:0006930]; T cell mediated immunity [GO:0002456]; tissue development [GO:0009888] GO:0001764; GO:0002456; GO:0005125; GO:0005576; GO:0005604; GO:0005654; GO:0005737; GO:0005829; GO:0006915; GO:0006930; GO:0007097; GO:0007265; GO:0007409; GO:0007411; GO:0008045; GO:0008283; GO:0009887; GO:0009888; GO:0014009; GO:0015629; GO:0016358; GO:0019724; GO:0030334; GO:0030517; GO:0030879; GO:0031012; GO:0032488; GO:0033564; GO:0042100; GO:0042472; GO:0045773; GO:0051963; GO:0060252; GO:0060603; GO:0061643; GO:0062023; GO:0071944; GO:0097475; GO:0098609; GO:1903975; GO:2000147 12824 XM_029347719.2 137 75 60 84 146 NA NA NA NA NA NA 12825 XM_044320504.1 1479 4335 1472 5471 3224 Q9Y2U8 5.46e-74 Inner nuclear membrane protein Man1 (LEM domain-containing protein 3) Homo sapiens (Human) negative regulation of activin receptor signaling pathway [GO:0032926]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear envelope organization [GO:0006998] GO:0005637; GO:0006998; GO:0016020; GO:0030512; GO:0030514; GO:0031490; GO:0031965; GO:0032926 12826 XR_006395899.1 1 0 0 7 0 NA NA NA NA NA NA 12827 XR_006397829.1 31 88 49 68 74 NA NA NA NA NA NA 12828 XR_006396826.1 99 204 57 62 127 NA NA NA NA NA NA 12829 XM_029358287.2 20 5 5 13 20 NA NA NA NA NA NA 12830 XM_044318201.1 449 157 219 403 513 Q05895 2.75e-109 Thrombospondin-3 Mus musculus (Mouse) bone trabecula formation [GO:0060346]; cell adhesion [GO:0007155]; growth plate cartilage development [GO:0003417]; ossification involved in bone maturation [GO:0043931] GO:0003417; GO:0005509; GO:0005576; GO:0007155; GO:0008201; GO:0043931; GO:0048471; GO:0060346; GO:0062023 12831 XM_044311666.1 121 229 148 130 601 Q921Y2 3.65e-70 U3 small nucleolar ribonucleoprotein protein IMP3 (U3 snoRNP protein IMP3) Mus musculus (Mouse) ribosomal small subunit biogenesis [GO:0042274]; rRNA processing [GO:0006364] GO:0003735; GO:0005634; GO:0005654; GO:0005730; GO:0006364; GO:0015935; GO:0019843; GO:0030515; GO:0030684; GO:0032040; GO:0034457; GO:0042274 12832 XM_029352472.2 12 14 21 18 18 Q3V2A7 1.42e-34 Glutamine-rich protein 2 Mus musculus (Mouse) cell projection assembly [GO:0030031]; flagellated sperm motility [GO:0030317]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059] GO:0005634; GO:0005737; GO:0030031; GO:0030317; GO:0031965; GO:0036126; GO:2000059 12833 XM_029329845.2 44 45 40 40 78 NA NA NA NA NA NA 12834 XM_044324676.1 6810 3483 3671 7758 5625 P47791 0 Glutathione reductase, mitochondrial (GR) (GRase) (EC 1.8.1.7) Mus musculus (Mouse) cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glutathione metabolic process [GO:0006749]; spermatogenesis [GO:0007283] GO:0004362; GO:0005739; GO:0005829; GO:0006749; GO:0007283; GO:0009897; GO:0034599; GO:0042802; GO:0043295; GO:0045454; GO:0050660; GO:0050661 12835 XM_029344622.2 116 86 105 300 139 NA NA NA NA NA NA 12836 XM_044316718.1 0 47 89 0 0 P14207 1.56e-35 Folate receptor beta (FR-beta) (Folate receptor 2) (Folate receptor, fetal/placental) (Placental folate-binding protein) (FBP) Homo sapiens (Human) cell adhesion [GO:0007155]; folic acid transport [GO:0015884]; fusion of sperm to egg plasma membrane involved in single fertilization [GO:0007342]; inflammatory response [GO:0006954]; positive regulation of cell population proliferation [GO:0008284]; sperm-egg recognition [GO:0035036] GO:0005542; GO:0005576; GO:0005886; GO:0006954; GO:0007155; GO:0007342; GO:0008284; GO:0009897; GO:0009986; GO:0015884; GO:0035036; GO:0038023; GO:0061714 12837 XM_029358120.2 40 17 14 33 37 NA NA NA NA NA NA 12838 XM_029330253.2 1389 1581 886 1423 1084 Q9NXJ5 1.06e-51 Pyroglutamyl-peptidase 1 (EC 3.4.19.3) (5-oxoprolyl-peptidase) (Pyroglutamyl aminopeptidase I) (PAP-I) (Pyroglutamyl-peptidase I) (PGP-I) (Pyrrolidone-carboxylate peptidase) Homo sapiens (Human) protein catabolic process [GO:0030163]; proteolysis [GO:0006508] GO:0005829; GO:0006508; GO:0016920; GO:0030163 12839 XM_044319152.1 594 119 108 675 372 NA NA NA NA NA NA 12840 XM_029345665.2 2608 2243 1306 2122 2000 P70618 0 Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC 2.7.11.24) (CRK1) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; bone development [GO:0060348]; cartilage condensation [GO:0001502]; cell morphogenesis [GO:0000902]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to ionizing radiation [GO:0071479]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to lipoteichoic acid [GO:0071223]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to UV-B [GO:0071493]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular response to virus [GO:0098586]; chondrocyte differentiation [GO:0002062]; DNA damage checkpoint signaling [GO:0000077]; fatty acid oxidation [GO:0019395]; glucose import [GO:0046323]; glucose metabolic process [GO:0006006]; intracellular signal transduction [GO:0035556]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of hippo signaling [GO:0035331]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; p38MAPK cascade [GO:0038066]; peptidyl-serine phosphorylation [GO:0018105]; placenta development [GO:0001890]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cyclase activity [GO:0031281]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose import [GO:0046326]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of myotube differentiation [GO:0010831]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cytokine production involved in inflammatory response [GO:1900015]; regulation of DNA-templated transcription [GO:0006355]; regulation of ossification [GO:0030278]; regulation of synaptic membrane adhesion [GO:0099179]; regulation of transcription by RNA polymerase II [GO:0006357]; response to dietary excess [GO:0002021]; response to glucose [GO:0009749]; response to insulin [GO:0032868]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to muscle stretch [GO:0035994]; signal transduction in response to DNA damage [GO:0042770]; skeletal muscle tissue development [GO:0007519]; stem cell differentiation [GO:0048863]; stress-activated MAPK cascade [GO:0051403]; stress-induced premature senescence [GO:0090400]; striated muscle cell differentiation [GO:0051146]; transcription by RNA polymerase II [GO:0006366]; transmembrane receptor protein serine/threonine kinase signaling pathway [GO:0007178]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] GO:0000077; GO:0000165; GO:0000902; GO:0000922; GO:0001502; GO:0001525; GO:0001649; GO:0001890; GO:0002021; GO:0002062; GO:0004672; GO:0004674; GO:0004707; GO:0005524; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0006006; GO:0006355; GO:0006357; GO:0006366; GO:0006468; GO:0006915; GO:0006974; GO:0007178; GO:0007519; GO:0008022; GO:0009749; GO:0010628; GO:0010831; GO:0016301; GO:0018105; GO:0019211; GO:0019395; GO:0019899; GO:0019903; GO:0030278; GO:0030316; GO:0031281; GO:0031663; GO:0032495; GO:0032496; GO:0032735; GO:0032868; GO:0035331; GO:0035556; GO:0035924; GO:0035994; GO:0038066; GO:0042307; GO:0042770; GO:0045648; GO:0045663; GO:0045944; GO:0046323; GO:0046326; GO:0046777; GO:0048010; GO:0048273; GO:0048863; GO:0051146; GO:0051403; GO:0051525; GO:0060045; GO:0060348; GO:0071222; GO:0071223; GO:0071356; GO:0071479; GO:0071493; GO:0090090; GO:0090336; GO:0090400; GO:0098586; GO:0098978; GO:0099179; GO:0106310; GO:0140537; GO:1900015; GO:1901741; GO:2000379 12841 XM_044318904.1 0 80 0 0 0 Q5RD26 8.22e-45 Heterogeneous nuclear ribonucleoprotein H2 (hnRNP H2) (Heterogeneous nuclear ribonucleoprotein H') (hnRNP H') [Cleaved into: Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed] Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003723; GO:0005654; GO:1990904 12842 XM_029345106.2 32 25 99 59 139 Q9DBW0 1.87e-142 Cytochrome P450 4V2 (Docosahexaenoic acid omega-hydroxylase CYP4V2) (EC 1.14.14.79) (Long-chain fatty acid omega-monooxygenase) (EC 1.14.14.80) Mus musculus (Mouse) fatty acid omega-oxidation [GO:0010430] GO:0005506; GO:0005789; GO:0010430; GO:0020037; GO:0102033 12843 XM_044327907.1 76 11 21 164 300 P21956 2.27e-49 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (SED1) (Sperm surface protein SP47) (MP47) Mus musculus (Mouse) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0007155; GO:0007338; GO:0009897; GO:0043277; GO:0062023 12844 XM_029358164.2 122 27 55 97 81 NA NA NA NA NA NA 12845 XM_044311667.1 219 244 156 228 176 Q6BN80 3.78e-21 Diphthine methyl ester synthase (EC 2.1.1.314) (Diphthamide biosynthesis methyltransferase) Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii) methylation [GO:0032259]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183] GO:0004164; GO:0005737; GO:0017183; GO:0032259 12846 XM_044311667.1 219 244 156 228 176 Q6BN80 3.78e-21 Diphthine methyl ester synthase (EC 2.1.1.314) (Diphthamide biosynthesis methyltransferase) Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii) methylation [GO:0032259]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183] GO:0004164; GO:0005737; GO:0017183; GO:0032259 12847 XM_044315304.1 0 0 0 0 21 Q66H56 4.74e-55 TELO2-interacting protein 2 Rattus norvegicus (Rat) NA GO:0005654; GO:0005813; GO:0005829; GO:0070209; GO:0110078 12848 XM_029350651.2 278 295 157 430 383 P29120 0 Neuroendocrine convertase 1 (NEC 1) (EC 3.4.21.93) (Prohormone convertase 1) (Proprotein convertase 1) (PC1) Homo sapiens (Human) cell-cell signaling [GO:0007267]; insulin processing [GO:0030070]; neurogenesis [GO:0022008]; pancreas development [GO:0031016]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; pituitary gland development [GO:0021983]; positive regulation of protein secretion [GO:0050714]; protein autoprocessing [GO:0016540]; protein processing [GO:0016485]; proteolysis [GO:0006508]; response to axon injury [GO:0048678]; response to calcium ion [GO:0051592]; response to chlorate [GO:0010157]; response to fatty acid [GO:0070542]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; response to morphine [GO:0043278]; response to nutrient levels [GO:0031667]; response to peptide hormone [GO:0043434]; response to xenobiotic stimulus [GO:0009410] GO:0004252; GO:0005615; GO:0005791; GO:0005802; GO:0006508; GO:0007267; GO:0009410; GO:0009749; GO:0010157; GO:0016020; GO:0016485; GO:0016486; GO:0016540; GO:0021983; GO:0022008; GO:0030070; GO:0030133; GO:0030425; GO:0031016; GO:0031667; GO:0032496; GO:0034774; GO:0042802; GO:0043005; GO:0043043; GO:0043204; GO:0043278; GO:0043434; GO:0043679; GO:0048471; GO:0048678; GO:0050714; GO:0051384; GO:0051592; GO:0070542; GO:0070555 12849 XM_029349394.2 182 95 75 78 187 F1R8P4 4.62e-79 Glycine receptor subunit alpha-2 Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0004888; GO:0005254; GO:0016594; GO:0016933; GO:0022824; GO:0034707; GO:0042995; GO:0045211; GO:0046872 12850 XM_029340481.2 802 1122 443 1128 916 Q3TUL7 6.16e-74 DDB1- and CUL4-associated factor 17 Mus musculus (Mouse) protein ubiquitination [GO:0016567] GO:0005654; GO:0005730; GO:0005829; GO:0016020; GO:0016567; GO:0080008 12851 XR_003824667.2 38 26 0 9 64 NA NA NA NA NA NA 12852 XM_029342664.2 33 17 8 31 74 Q9QXW2 7.15e-37 F-box/WD repeat-containing protein 5 (F-box and WD-40 domain-containing protein 5) Mus musculus (Mouse) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of centrosome duplication [GO:0010824]; regulation of mitotic nuclear division [GO:0007088]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0005737; GO:0007088; GO:0010824; GO:0016567; GO:0019005; GO:0019901; GO:0031146; GO:0043161; GO:0080008 12853 XM_029342664.2 33 17 8 31 74 Q9QXW2 6.35e-31 F-box/WD repeat-containing protein 5 (F-box and WD-40 domain-containing protein 5) Mus musculus (Mouse) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of centrosome duplication [GO:0010824]; regulation of mitotic nuclear division [GO:0007088]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0005737; GO:0007088; GO:0010824; GO:0016567; GO:0019005; GO:0019901; GO:0031146; GO:0043161; GO:0080008 12854 XM_044326131.1 52 15 152 89 471 NA NA NA NA NA NA 12855 XM_029358425.2 2207 1780 1319 3241 3277 A1L1W9 6.87e-59 Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10) Danio rerio (Zebrafish) (Brachydanio rerio) aromatic amino acid transport [GO:0015801]; thyroid hormone transport [GO:0070327] GO:0005302; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0070327 12856 XM_044316034.1 1097 501 115 562 58 Q08DY9 9.1e-36 Caspase-3 (CASP-3) (EC 3.4.22.56) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12] Bos taurus (Bovine) positive regulation of amyloid-beta formation [GO:1902004]; proteolysis [GO:0006508]; regulation of protein stability [GO:0031647] GO:0004175; GO:0005737; GO:0006508; GO:0031647; GO:0097153; GO:0097199; GO:0097200; GO:1902004 12857 XM_044317053.1 100 79 44 0 59 Q96D71 1.1e-25 RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1) Homo sapiens (Human) endocytosis [GO:0006897]; endosomal transport [GO:0016197] GO:0005509; GO:0005829; GO:0005886; GO:0005905; GO:0006897; GO:0016197; GO:0017124 12858 XR_003825539.2 78 182 105 46 108 NA NA NA NA NA NA 12859 XM_029354783.2 3052 2726 2311 1845 670 Q8VCM4 1.89e-80 Lipoyltransferase 1, mitochondrial (EC 2.3.1.-) (Lipoate biosynthesis protein) (Lipoate-protein ligase) (Lipoyl ligase) Mus musculus (Mouse) protein lipoylation [GO:0009249] GO:0005737; GO:0005739; GO:0009249; GO:0017118 12860 XM_029334978.2 4128 4078 2334 6245 4166 P83852 2.58e-132 Carboxypeptidase D (EC 3.4.17.22) (CPD-2) (Metallocarboxypeptidase D) Lophonetta specularioides (Crested duck) (Anas specularioides) proteolysis [GO:0006508] GO:0004181; GO:0006508; GO:0008270; GO:0016020 12861 XM_029346343.2 267 271 239 147 146 Q9GZZ6 1.45e-74 Neuronal acetylcholine receptor subunit alpha-10 (Nicotinic acetylcholine receptor subunit alpha-10) (NACHR alpha-10) Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; inner ear morphogenesis [GO:0042472]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; nervous system process [GO:0050877]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; regulation of cell population proliferation [GO:0042127]; regulation of membrane potential [GO:0042391]; response to auditory stimulus [GO:0010996]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271] GO:0004888; GO:0005102; GO:0005231; GO:0005262; GO:0005886; GO:0005892; GO:0007165; GO:0007204; GO:0007268; GO:0007271; GO:0010996; GO:0016020; GO:0022848; GO:0030424; GO:0030594; GO:0034220; GO:0042127; GO:0042391; GO:0042472; GO:0043005; GO:0043204; GO:0045202; GO:0050877; GO:0050910; GO:0051899; GO:0070373; GO:0098981; GO:0099634; GO:1904315 12862 XM_029323587.2 0 0 0 0 298 Q9I8E6 0 Coatomer subunit gamma-2 (Gamma-2-coat protein) (Gamma-2-COP) Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0005198; GO:0006886; GO:0016192; GO:0030126 12863 XM_044310778.1 166 319 4 66 40 NA NA NA NA NA NA 12864 XR_006392465.1 1764 1087 272 301 745 NA NA NA NA NA NA 12865 XM_044316845.1 0 0 0 95 20 NA NA NA NA NA NA 12866 XM_029351023.2 99 262 371 151 437 NA NA NA NA NA NA 12867 XM_044324972.1 633 383 321 707 862 P10079 8.71e-85 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 12868 XM_044324972.1 633 383 321 707 862 P10079 2.24e-82 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 12869 XM_044324972.1 633 383 321 707 862 P10079 1.37e-79 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 12870 XM_044324972.1 633 383 321 707 862 P10079 9.57e-73 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 12871 XM_044324972.1 633 383 321 707 862 P10079 1.1e-72 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 12872 XM_044324972.1 633 383 321 707 862 P10079 3.41e-71 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 12873 XM_044324972.1 633 383 321 707 862 P10079 4.45e-67 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 12874 XM_044324972.1 633 383 321 707 862 P10079 1.96e-65 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 12875 XM_044324972.1 633 383 321 707 862 P10079 1.06e-58 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 12876 XM_044324972.1 633 383 321 707 862 P10079 1.09e-58 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 12877 XM_044324972.1 633 383 321 707 862 P10079 2.51e-57 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 12878 XM_044324972.1 633 383 321 707 862 P10079 5.58e-56 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 12879 XM_044324972.1 633 383 321 707 862 P10079 2.23e-52 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 12880 XM_044324972.1 633 383 321 707 862 P10079 7.36e-36 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 12881 XM_029330548.2 913 546 538 513 729 P50613 1.29e-174 Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein kinase) (p39 Mo15) (CDK-activating kinase 1) (Cell division protein kinase 7) (Serine/threonine-protein kinase 1) (TFIIH basal transcription factor complex kinase subunit) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; DNA repair [GO:0006281]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of cell cycle [GO:0051726]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription initiation at RNA polymerase II promoter [GO:0006367] GO:0000079; GO:0000439; GO:0001650; GO:0001673; GO:0004672; GO:0004674; GO:0004693; GO:0005524; GO:0005634; GO:0005654; GO:0005675; GO:0005737; GO:0005829; GO:0005886; GO:0006281; GO:0006366; GO:0006367; GO:0006468; GO:0007049; GO:0008022; GO:0008094; GO:0008353; GO:0019907; GO:0042795; GO:0045944; GO:0048471; GO:0050821; GO:0051301; GO:0051726; GO:0070516; GO:0070816; GO:0070985; GO:0106310; GO:2000045 12882 XM_044319543.1 18 0 0 0 0 NA NA NA NA NA NA 12883 XM_044317441.1 0 3 0 0 34 O62852 5.41e-60 Short transient receptor potential channel 5 (Rtrp5) (TrpC5) (Capacitative calcium entry channel 2) (CCE2) Oryctolagus cuniculus (Rabbit) neuron apoptotic process [GO:0051402]; phosphatidylserine exposure on apoptotic cell surface [GO:0070782] GO:0005262; GO:0005886; GO:0034704; GO:0051402; GO:0070679; GO:0070782 12884 XM_044328849.1 4 9 13 18 23 NA NA NA NA NA NA 12885 XM_029340195.2 150 207 207 183 376 P46735 0 Unconventional myosin-Ib (MIH-L) (Myosin I alpha) (MMI-alpha) (MMIa) Mus musculus (Mouse) actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; actin filament-based movement [GO:0030048]; post-Golgi vesicle-mediated transport [GO:0006892]; transferrin transport [GO:0033572]; vesicle transport along actin filament [GO:0030050] GO:0000146; GO:0003774; GO:0003779; GO:0005516; GO:0005524; GO:0005546; GO:0005547; GO:0005737; GO:0005769; GO:0005884; GO:0005886; GO:0005902; GO:0005903; GO:0006892; GO:0007015; GO:0010008; GO:0015629; GO:0016459; GO:0030048; GO:0030050; GO:0030175; GO:0031982; GO:0032588; GO:0033572; GO:0045177; GO:0048471; GO:0051015; GO:0051017; GO:0071944 12886 XM_029350029.2 34 8 25 46 39 P56706 2.81e-100 Protein Wnt-7b Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; cellular oxygen homeostasis [GO:0032364]; cellular response to retinoic acid [GO:0071300]; central nervous system vasculogenesis [GO:0022009]; chorio-allantoic fusion [GO:0060710]; developmental growth involved in morphogenesis [GO:0060560]; embryonic organ development [GO:0048568]; embryonic placenta morphogenesis [GO:0060669]; establishment or maintenance of polarity of embryonic epithelium [GO:0016332]; fibroblast proliferation [GO:0048144]; forebrain regionalization [GO:0021871]; homeostatic process [GO:0042592]; in utero embryonic development [GO:0001701]; inner medullary collecting duct development [GO:0072061]; lens fiber cell development [GO:0070307]; lobar bronchus development [GO:0060482]; lung development [GO:0030324]; lung epithelium development [GO:0060428]; lung morphogenesis [GO:0060425]; mammary gland epithelium development [GO:0061180]; metanephric collecting duct development [GO:0072205]; metanephric epithelium development [GO:0072207]; metanephric loop of Henle development [GO:0072236]; metanephros morphogenesis [GO:0003338]; neuron differentiation [GO:0030182]; neuron projection morphogenesis [GO:0048812]; outer medullary collecting duct development [GO:0072060]; positive regulation of JNK cascade [GO:0046330]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell projection size [GO:0032536]; renal inner medulla development [GO:0072053]; renal outer medulla development [GO:0072054]; response to glucocorticoid [GO:0051384]; stem cell proliferation [GO:0072089]; synapse organization [GO:0050808]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055] GO:0001701; GO:0003338; GO:0005109; GO:0005125; GO:0005576; GO:0005615; GO:0005788; GO:0005796; GO:0005886; GO:0016055; GO:0016332; GO:0021871; GO:0022009; GO:0030182; GO:0030324; GO:0030666; GO:0032364; GO:0032536; GO:0042592; GO:0045165; GO:0045669; GO:0046330; GO:0048018; GO:0048144; GO:0048568; GO:0048812; GO:0050808; GO:0051384; GO:0060070; GO:0060425; GO:0060428; GO:0060482; GO:0060535; GO:0060560; GO:0060669; GO:0060710; GO:0061180; GO:0070062; GO:0070307; GO:0071300; GO:0072053; GO:0072054; GO:0072060; GO:0072061; GO:0072089; GO:0072205; GO:0072207; GO:0072236 12887 XM_044314668.1 46 34 13 109 232 NA NA NA NA NA NA 12888 XR_006394265.1 11 4 43 9 189 NA NA NA NA NA NA 12889 XM_044328785.1 0 0 0 0 14 NA NA NA NA NA NA 12890 XM_029352454.2 238 0 81 52 96 Q6IMK3 2.09e-95 DnaJ homolog subfamily C member 27 (Rab and DnaJ domain-containing protein) Danio rerio (Zebrafish) (Brachydanio rerio) intracellular protein transport [GO:0006886] GO:0003924; GO:0005525; GO:0005634; GO:0006886 12891 XM_044318426.1 59 13 78 24 280 NA NA NA NA NA NA 12892 XM_029336836.2 152 51 31 89 52 O42409 1.33e-95 Zinc finger protein Gfi-1b (Growth factor-independent protein 1B) Gallus gallus (Chicken) chromatin organization [GO:0006325]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001227; GO:0005654; GO:0006325; GO:0006357; GO:0046872 12893 XM_029336836.2 152 51 31 89 52 O42409 1.36e-21 Zinc finger protein Gfi-1b (Growth factor-independent protein 1B) Gallus gallus (Chicken) chromatin organization [GO:0006325]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001227; GO:0005654; GO:0006325; GO:0006357; GO:0046872 12894 XM_029353470.2 223 65 56 206 404 Q3THE2 6.45e-69 Myosin regulatory light chain 12B (Myosin regulatory light chain 2-B, smooth muscle isoform) (Myosin regulatory light chain 20 kDa) (MLC20) (Myosin regulatory light chain MRLC2) Mus musculus (Mouse) regulation of cell shape [GO:0008360] GO:0001725; GO:0005509; GO:0005737; GO:0005903; GO:0005938; GO:0008360; GO:0016460; GO:0030016; GO:0030018; GO:0032036; GO:0032991; GO:0045177 12895 XM_044312209.1 15 0 0 21 9 Q80XJ3 3.32e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 12896 XM_044317200.1 0 1 0 39 0 B8JKV0 1.34e-47 Protein AMN1 homolog Mus musculus (Mouse) cobalamin transport [GO:0015889]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0015889; GO:0019005; GO:0031146; GO:0031528; GO:0038024 12897 XM_029335453.2 2215 2586 1357 2484 2409 NA NA NA NA NA NA 12898 XM_029345348.2 5 0 1 4 15 Q9EQD2 2.21e-28 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 12899 XM_044317969.1 60 12 0 17 0 NA NA NA NA NA NA 12900 XM_029334633.2 0 0 94 263 0 Q69Z28 6.88e-107 A disintegrin and metalloproteinase with thrombospondin motifs 16 (ADAM-TS 16) (ADAM-TS16) (ADAMTS-16) (EC 3.4.24.-) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; extracellular matrix organization [GO:0030198]; male gamete generation [GO:0048232]; proteolysis [GO:0006508]; regulation of cilium assembly [GO:1902017]; regulation of systemic arterial blood pressure [GO:0003073] GO:0001658; GO:0003073; GO:0004222; GO:0005576; GO:0006508; GO:0030198; GO:0031012; GO:0046872; GO:0048232; GO:1902017 12901 XM_029342068.2 0 16 9 30 25 NA NA NA NA NA NA 12902 XM_029357079.2 766 706 504 925 847 A8K8P3 1.85e-94 Protein SFI1 homolog (hSFI1) Homo sapiens (Human) NA GO:0005814; GO:0005829; GO:0019902 12903 XM_029334142.2 68 140 30 303 339 NA NA NA NA NA NA 12904 XM_044322353.1 87 63 41 17 46 NA NA NA NA NA NA 12905 XM_044314791.1 19 5 6 2 73 NA NA NA NA NA NA 12906 XM_044312608.1 1293 304 2084 735 5505 P15043 3.29e-22 ATP-dependent DNA helicase RecQ (EC 3.6.4.12) Escherichia coli (strain K12) cellular response to DNA damage stimulus [GO:0006974]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; SOS response [GO:0009432] GO:0003677; GO:0003678; GO:0005524; GO:0005694; GO:0005737; GO:0006260; GO:0006281; GO:0006310; GO:0006974; GO:0008094; GO:0008270; GO:0009378; GO:0009432; GO:0016887; GO:0017116; GO:0017117; GO:0030894; GO:0032508; GO:0043138; GO:0043590; GO:0046914 12907 XM_029330514.2 24 50 172 150 80 NA NA NA NA NA NA 12908 XM_044318361.1 2036 1137 1235 2123 2014 Q28WQ1 0 Kinesin-like protein unc-104 Drosophila pseudoobscura pseudoobscura (Fruit fly) synaptic vesicle transport [GO:0048489]; vesicle transport along microtubule [GO:0047496] GO:0003777; GO:0005524; GO:0005737; GO:0005874; GO:0005875; GO:0008017; GO:0047496; GO:0048489 12909 XM_044318361.1 2036 1137 1235 2123 2014 Q28WQ1 2.79e-22 Kinesin-like protein unc-104 Drosophila pseudoobscura pseudoobscura (Fruit fly) synaptic vesicle transport [GO:0048489]; vesicle transport along microtubule [GO:0047496] GO:0003777; GO:0005524; GO:0005737; GO:0005874; GO:0005875; GO:0008017; GO:0047496; GO:0048489 12910 XM_044311241.1 3 0 20 0 176 NA NA NA NA NA NA 12911 XM_044311992.1 5 8 10 5 21 NA NA NA NA NA NA 12912 XM_044319529.1 4 19 3 17 21 NA NA NA NA NA NA 12913 XR_006394280.1 1 5 0 13 5 NA NA NA NA NA NA 12914 XM_044314425.1 11 0 0 11 5 Q96AY4 9.37e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12915 XM_029337221.2 209 148 101 192 162 Q9H7B4 3.99e-79 Histone-lysine N-methyltransferase SMYD3 (EC 2.1.1.354) (SET and MYND domain-containing protein 3) (Zinc finger MYND domain-containing protein 1) Homo sapiens (Human) cellular response to dexamethasone stimulus [GO:0071549]; establishment of protein localization [GO:0045184]; histone lysine methylation [GO:0034968]; myotube cell development [GO:0014904]; negative regulation of protein kinase activity [GO:0006469]; nucleosome assembly [GO:0006334]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000978; GO:0000993; GO:0001162; GO:0005634; GO:0005654; GO:0005829; GO:0006334; GO:0006469; GO:0014904; GO:0018024; GO:0033138; GO:0034968; GO:0042800; GO:0045184; GO:0045944; GO:0046872; GO:0071549 12916 XM_029344480.2 89 164 83 89 68 NA NA NA NA NA NA 12917 XM_044328494.1 216 0 49 98 127 Q8CEE6 3.97e-116 PAS domain-containing serine/threonine-protein kinase (PAS-kinase) (PASKIN) (EC 2.7.11.1) Mus musculus (Mouse) energy homeostasis [GO:0097009]; intracellular signal transduction [GO:0035556]; negative regulation of glycogen biosynthetic process [GO:0045719]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of glucagon secretion [GO:0070092]; regulation of respiratory gaseous exchange [GO:0043576] GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006468; GO:0035091; GO:0035556; GO:0043576; GO:0045719; GO:0046777; GO:0070092; GO:0097009; GO:0106310 12918 XM_044328494.1 216 0 49 98 127 Q8CEE6 2.93e-63 PAS domain-containing serine/threonine-protein kinase (PAS-kinase) (PASKIN) (EC 2.7.11.1) Mus musculus (Mouse) energy homeostasis [GO:0097009]; intracellular signal transduction [GO:0035556]; negative regulation of glycogen biosynthetic process [GO:0045719]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of glucagon secretion [GO:0070092]; regulation of respiratory gaseous exchange [GO:0043576] GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006468; GO:0035091; GO:0035556; GO:0043576; GO:0045719; GO:0046777; GO:0070092; GO:0097009; GO:0106310 12919 XM_044307094.1 16 0 0 0 0 A5PJU6 2.83e-43 Hydroxylysine kinase (5-hydroxy-L-lysine kinase) (EC 2.7.1.81) (Aminoglycoside phosphotransferase domain-containing protein 1) Bos taurus (Bovine) phosphorylation [GO:0016310] GO:0005737; GO:0016310; GO:0019202; GO:0047992 12920 XM_044319297.1 53 15 11 104 49 NA NA NA NA NA NA 12921 XM_029356844.2 0 0 14 1 14 NA NA NA NA NA NA 12922 XM_044315094.1 0 32 0 0 76 NA NA NA NA NA NA 12923 XM_029345471.2 984 1310 607 980 1069 Q5E9X1 2.09e-72 Nuclear transcription factor Y subunit gamma (CAAT box DNA-binding protein subunit C) (Nuclear transcription factor Y subunit C) (NF-YC) Bos taurus (Bovine) histone H3-K4 trimethylation [GO:0080182]; regulation of DNA-templated transcription [GO:0006355]; regulation of histone acetylation [GO:0035065] GO:0000978; GO:0001228; GO:0005634; GO:0005654; GO:0006355; GO:0016602; GO:0032993; GO:0035065; GO:0046982; GO:0080182 12924 XM_044310745.1 52 0 0 0 26 NA NA NA NA NA NA 12925 XM_029346077.2 1091 22 774 73 1036 NA NA NA NA NA NA 12926 XM_029350840.2 3808 3011 2763 3580 4186 O55029 0 Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP) (p102) Mus musculus (Mouse) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; toxin transport [GO:1901998] GO:0000139; GO:0005080; GO:0005198; GO:0005794; GO:0005829; GO:0006886; GO:0006888; GO:0006890; GO:0006891; GO:0030126; GO:1901998 12927 XM_044315956.1 0 0 4 2 11 NA NA NA NA NA NA 12928 XM_029356116.2 6 33 30 37 28 Q9Y5X5 1.91e-33 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (G-protein coupled receptor HLWAR77) (Neuropeptide G-protein coupled receptor) Homo sapiens (Human) detection of abiotic stimulus [GO:0009582]; G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0009582; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 12929 XM_044317646.1 107 35 20 26 120 Q66PG1 7.87e-37 Xylosyl- and glucuronyltransferase LARGE2s (EC 2.4.-.-) (Glycosyltransferase-like 1B) (LARGE xylosyl- and glucuronyltransferase 2) [Includes: Alpha-1,3-xylosyltransferase LARGE2 (EC 2.4.2.-); Beta-1,3-glucuronyltransferase LARGE2 (EC 2.4.1.-)] Danio rerio (Zebrafish) (Brachydanio rerio) protein glycosylation [GO:0006486]; protein O-linked mannosylation [GO:0035269] GO:0000139; GO:0005794; GO:0006486; GO:0015020; GO:0035269; GO:0042285; GO:0046872 12930 XM_029327386.2 3363 4349 2694 4343 3257 Q9UPW0 1.68e-59 Forkhead box protein J3 Homo sapiens (Human) cell differentiation [GO:0030154]; male meiosis I [GO:0007141]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283] GO:0000785; GO:0000978; GO:0000981; GO:0001228; GO:0005634; GO:0006357; GO:0007141; GO:0007283; GO:0030154; GO:0043565; GO:0045944; GO:1990837 12931 XM_029354505.2 6 0 0 15 0 NA NA NA NA NA NA 12932 XR_006391472.1 1 103 1 137 1 Q9Y573 2.45e-41 Actin-binding protein IPP (Intracisternal A particle-promoted polypeptide) (IPP) (Kelch-like protein 27) Homo sapiens (Human) NA GO:0003779; GO:0005737; GO:0015629 12933 XM_029346417.2 6393 14254 9811 15295 17548 Q8BH04 0 Phosphoenolpyruvate carboxykinase [GTP], mitochondrial (PEPCK-M) (EC 4.1.1.32) Mus musculus (Mouse) cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; gluconeogenesis [GO:0006094]; glycerol biosynthetic process from pyruvate [GO:0046327]; hepatocyte differentiation [GO:0070365]; NADH oxidation [GO:0006116]; oxaloacetate metabolic process [GO:0006107]; positive regulation of insulin secretion [GO:0032024]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; response to lipid [GO:0033993]; response to starvation [GO:0042594] GO:0004611; GO:0004613; GO:0005525; GO:0005739; GO:0005759; GO:0005829; GO:0006090; GO:0006094; GO:0006107; GO:0006116; GO:0019543; GO:0030145; GO:0032024; GO:0032869; GO:0033993; GO:0042594; GO:0046327; GO:0070365; GO:0071333; GO:0071549 12934 XM_029334527.2 0 17 32 179 106 NA NA NA NA NA NA 12935 XM_044328909.1 2395 1199 750 2062 1679 Q6NYU2 5.57e-133 Probable helicase with zinc finger domain (EC 3.6.4.-) Danio rerio (Zebrafish) (Brachydanio rerio) RNA-mediated post-transcriptional gene silencing [GO:0035194] GO:0003677; GO:0003700; GO:0003723; GO:0004386; GO:0005524; GO:0005634; GO:0005829; GO:0016787; GO:0035194; GO:0043186; GO:0046872 12936 XM_029348003.2 92 5 51 92 21 NA NA NA NA NA NA 12937 XR_003823469.2 11 0 2 22 13 NA NA NA NA NA NA 12938 XM_044317951.1 26 2 23 12 7 Q09575 2.06e-32 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 12939 XM_044311326.1 6 0 10 9 8 NA NA NA NA NA NA 12940 XM_029326859.2 62 278 31 229 104 F8J3H2 7.65e-23 NA NA NA NA 12941 XM_044316191.1 17 0 4 0 6 NA NA NA NA NA NA 12942 XM_044315923.1 0 0 11 0 0 NA NA NA NA NA NA 12943 XM_044311864.1 0 96 3 1 0 NA NA NA NA NA NA 12944 XM_029340388.2 0 218 960 1403 1327 E9QAT4 1.15e-45 Protein transport protein Sec16A (SEC16 homolog A) (p250) Mus musculus (Mouse) autophagy [GO:0006914]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; Golgi to plasma membrane transport [GO:0006893]; protein exit from endoplasmic reticulum [GO:0032527]; protein localization to endoplasmic reticulum exit site [GO:0070973]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; response to endoplasmic reticulum stress [GO:0034976] GO:0000139; GO:0005789; GO:0005829; GO:0006888; GO:0006893; GO:0006914; GO:0007029; GO:0007030; GO:0012507; GO:0031090; GO:0032527; GO:0034976; GO:0048208; GO:0048471; GO:0050821; GO:0070971; GO:0070973; GO:0072659 12945 XM_029337668.2 92 30 32 59 61 Q8BH18 7.96e-136 Transmembrane protein 117 Mus musculus (Mouse) intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059] GO:0005783; GO:0005886; GO:0070059 12946 XM_029337668.2 92 30 32 59 61 Q8BH18 6.6e-126 Transmembrane protein 117 Mus musculus (Mouse) intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059] GO:0005783; GO:0005886; GO:0070059 12947 XR_006394830.1 9 0 22 37 0 NA NA NA NA NA NA 12948 XM_044308039.1 18 41 27 1 100 NA NA NA NA NA NA 12949 XM_029328530.2 106 78 10 60 37 P85108 0 Tubulin beta-2A chain Rattus norvegicus (Rat) cerebral cortex development [GO:0021987]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764] GO:0000226; GO:0000278; GO:0001764; GO:0003924; GO:0005200; GO:0005525; GO:0005737; GO:0005874; GO:0021987; GO:0045171; GO:0046872; GO:0072686 12950 XM_044308098.1 4026 2096 2077 4083 3862 P41233 0 Phospholipid-transporting ATPase ABCA1 (EC 7.6.2.1) (ATP-binding cassette sub-family A member 1) (ATP-binding cassette transporter 1) (ABC-1) (ATP-binding cassette 1) Mus musculus (Mouse) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to retinoic acid [GO:0071300]; cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; cholesterol transport [GO:0030301]; endosomal transport [GO:0016197]; establishment of localization in cell [GO:0051649]; export across plasma membrane [GO:0140115]; G protein-coupled receptor signaling pathway [GO:0007186]; high-density lipoprotein particle assembly [GO:0034380]; intracellular cholesterol transport [GO:0032367]; lipid transport [GO:0006869]; lipoprotein biosynthetic process [GO:0042158]; lipoprotein metabolic process [GO:0042157]; lysosome organization [GO:0007040]; peptide secretion [GO:0002790]; phagocytosis, engulfment [GO:0006911]; phospholipid efflux [GO:0033700]; phospholipid homeostasis [GO:0055091]; phospholipid translocation [GO:0045332]; phospholipid transport [GO:0015914]; platelet dense granule organization [GO:0060155]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of high-density lipoprotein particle assembly [GO:0090108]; protein lipidation [GO:0006497]; protein secretion [GO:0009306]; protein transmembrane transport [GO:0071806]; regulation of Cdc42 protein signal transduction [GO:0032489]; response to laminar fluid shear stress [GO:0034616]; reverse cholesterol transport [GO:0043691]; signal release [GO:0023061] GO:0002790; GO:0005102; GO:0005319; GO:0005524; GO:0005548; GO:0005768; GO:0005794; GO:0005886; GO:0006497; GO:0006869; GO:0006911; GO:0007040; GO:0007186; GO:0007189; GO:0008035; GO:0008203; GO:0008320; GO:0009306; GO:0009897; GO:0009986; GO:0010875; GO:0015914; GO:0016020; GO:0016197; GO:0016323; GO:0016887; GO:0019905; GO:0023061; GO:0030139; GO:0030301; GO:0031210; GO:0031267; GO:0032367; GO:0032489; GO:0033344; GO:0033700; GO:0034185; GO:0034186; GO:0034188; GO:0034380; GO:0034616; GO:0042157; GO:0042158; GO:0042626; GO:0042632; GO:0043231; GO:0043691; GO:0045121; GO:0045332; GO:0045335; GO:0046623; GO:0048471; GO:0051117; GO:0051649; GO:0055091; GO:0060155; GO:0071222; GO:0071300; GO:0071806; GO:0090108; GO:0090554; GO:0090556; GO:0097708; GO:0120020; GO:0140115; GO:0140328; GO:0140359 12951 XM_044317866.1 14 0 33 49 107 Q8CG08 2.64e-44 Collagen triple helix repeat-containing protein 1 Rattus norvegicus (Rat) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005581; GO:0005615; GO:0005737; GO:0016477; GO:0016528; GO:0017147; GO:0031012; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0090090; GO:0090103; GO:0090177 12952 XM_029335964.2 326 680 292 305 384 Q9JL56 2.2e-46 Glycerophosphodiester phosphodiesterase 1 (Glycerophosphoinositol glycerophosphodiesterase GDE1) (EC 3.1.4.44) (Lysophospholipase D GDE1) (EC 3.1.4.-) (Membrane-interacting protein of RGS16) Mus musculus (Mouse) ethanolamine metabolic process [GO:0006580]; G protein-coupled receptor signaling pathway [GO:0007186]; N-acylethanolamine metabolic process [GO:0070291]; phospholipid metabolic process [GO:0006644] GO:0004622; GO:0005886; GO:0006580; GO:0006644; GO:0007186; GO:0008081; GO:0008889; GO:0016020; GO:0030659; GO:0046872; GO:0047395; GO:0070291 12953 XM_029353811.2 63 33 24 53 37 NA NA NA NA NA NA 12954 XM_029344634.2 50 35 39 50 74 Q5R5U3 8.16e-103 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 12955 XM_029344634.2 50 35 39 50 74 Q5R5U3 2.4e-98 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 12956 XM_029344634.2 50 35 39 50 74 Q5R5U3 4.1e-45 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 12957 XM_029344634.2 50 35 39 50 74 Q5R5U3 1.31e-31 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 12958 XM_029335376.2 143 60 90 155 190 NA NA NA NA NA NA 12959 XM_044327423.1 103 0 79 250 690 P50130 3.62e-38 D(1A) dopamine receptor (Dopamine D1 receptor) Sus scrofa (Pig) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; vasodilation [GO:0042311] GO:0004930; GO:0004952; GO:0005789; GO:0005886; GO:0007189; GO:0042311; GO:0043197 12960 XM_029335900.2 1503 1198 704 1044 1144 Q6P1M3 0 LLGL scribble cell polarity complex component 2 (HGL) (Lethal(2) giant larvae protein homolog 2) Homo sapiens (Human) cell division [GO:0051301]; cortical actin cytoskeleton organization [GO:0030866]; establishment of spindle orientation [GO:0051294]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; exocytosis [GO:0006887]; leucine transport [GO:0015820]; regulation of establishment or maintenance of cell polarity [GO:0032878]; regulation of Notch signaling pathway [GO:0008593]; regulation of protein secretion [GO:0050708] GO:0005096; GO:0005737; GO:0005829; GO:0005886; GO:0005912; GO:0006887; GO:0008593; GO:0015820; GO:0030165; GO:0030864; GO:0030866; GO:0032878; GO:0043231; GO:0045159; GO:0045197; GO:0050708; GO:0051294; GO:0051301 12961 XM_029352811.2 383 181 6 392 356 NA NA NA NA NA NA 12962 XM_029346705.2 535 563 314 432 249 NA NA NA NA NA NA 12963 XM_044319371.1 179 15 122 28 338 NA NA NA NA NA NA 12964 XM_029340786.2 341 363 972 520 323 NA NA NA NA NA NA 12965 XM_029325745.2 13 0 0 0 57 NA NA NA NA NA NA 12966 XM_029345472.2 42 175 107 293 0 Q5NU32 7.04e-85 Amine oxidase [flavin-containing] A (EC 1.4.3.21) (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A) Equus caballus (Horse) catecholamine metabolic process [GO:0006584]; neurotransmitter catabolic process [GO:0042135] GO:0005739; GO:0005741; GO:0006584; GO:0008131; GO:0042135; GO:0050660; GO:0052595; GO:0052596; GO:0097621 12967 XM_029326880.2 0 0 16 0 2 Q3V2Q8 6.41e-47 NEDD4-binding protein 2-like 1 Mus musculus (Mouse) NA NA 12968 XR_006395508.1 163 106 25 74 8 NA NA NA NA NA NA 12969 XM_044313622.1 3509 1596 1515 2510 2893 Q7SYM0 5.33e-102 Uridine-cytidine kinase 2-A (UCK 2-A) (EC 2.7.1.48) (Cytidine monophosphokinase 2-A) (Uridine monophosphokinase 2-A) Danio rerio (Zebrafish) (Brachydanio rerio) CTP salvage [GO:0044211]; phosphorylation [GO:0016310]; UMP salvage [GO:0044206] GO:0004849; GO:0005524; GO:0005737; GO:0005829; GO:0016310; GO:0043771; GO:0044206; GO:0044211 12970 XR_003828594.2 19 4 10 4 3 NA NA NA NA NA NA 12971 XR_006396330.1 930 633 496 603 774 A7RWD2 7.35e-70 Probable cytosolic iron-sulfur protein assembly protein CIAO1 homolog Nematostella vectensis (Starlet sea anemone) iron-sulfur cluster assembly [GO:0016226] GO:0016226; GO:0097361 12972 XM_029337606.2 249 198 115 209 258 NA NA NA NA NA NA 12973 XM_044328123.1 2078 1566 1086 1993 1703 C3YWU0 0 Alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucoside fucohydrolase) Branchiostoma floridae (Florida lancelet) (Amphioxus) fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139] GO:0004560; GO:0005576; GO:0005764; GO:0006004; GO:0016139 12974 XM_029343494.2 2228 1936 1167 1843 1441 Q2KJ46 0 26S proteasome non-ATPase regulatory subunit 3 (26S proteasome regulatory subunit RPN3) Bos taurus (Bovine) regulation of protein catabolic process [GO:0042176]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0006511; GO:0008541; GO:0022624; GO:0030234; GO:0042176 12975 XR_006392585.1 3 2 7 10 0 NA NA NA NA NA NA 12976 XR_006397532.1 2 21 3 0 15 NA NA NA NA NA NA 12977 XM_044317505.1 19 18 24 8 122 B8VIU6 1.36e-36 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 12978 XM_029343146.2 908 810 173 670 1114 Q9VPD3 1.01e-134 Phosphatidylserine synthase (EC 2.7.8.29) Drosophila melanogaster (Fruit fly) phosphatidylserine biosynthetic process [GO:0006659] GO:0005789; GO:0006659; GO:0012505; GO:0016780; GO:0106245; GO:0106258 12979 XM_044314820.1 0 6 0 0 0 NA NA NA NA NA NA 12980 XM_029329583.2 23 12 35 15 12 A4IGL7 3.68e-98 Peroxidasin (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0005576; GO:0005604; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0031012; GO:0042744; GO:0046872; GO:0051260; GO:0070207; GO:0070831; GO:0071711; GO:0140825 12981 XR_006393042.1 321 155 148 105 127 P16157 2.9e-76 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 12982 XR_006393042.1 321 155 148 105 127 P16157 1.22e-65 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 12983 XR_006393042.1 321 155 148 105 127 P16157 9.91e-50 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 12984 XM_029356095.2 8 9 32 4 12 Q8IWB6 8.21e-26 Inactive serine/threonine-protein kinase TEX14 (Protein kinase-like protein SgK307) (Sugen kinase 307) (Testis-expressed sequence 14) (Testis-expressed sequence 14 protein) Homo sapiens (Human) attachment of spindle microtubules to kinetochore [GO:0008608]; cell division [GO:0051301]; cellular response to leukemia inhibitory factor [GO:1990830]; intercellular bridge organization [GO:0043063]; male meiotic nuclear division [GO:0007140]; mitotic sister chromatid separation [GO:0051306]; mitotic spindle assembly checkpoint signaling [GO:0007094]; negative regulation of cytokinesis [GO:0032466]; negative regulation of protein binding [GO:0032091]; protein phosphorylation [GO:0006468] GO:0000776; GO:0004672; GO:0005524; GO:0005737; GO:0006468; GO:0007094; GO:0007140; GO:0008608; GO:0019901; GO:0030496; GO:0032091; GO:0032466; GO:0043063; GO:0045171; GO:0051301; GO:0051306; GO:0070062; GO:1990830 12985 XM_044309051.1 20 46 15 17 18 A1KZ92 5.18e-30 Probable oxidoreductase PXDNL (EC 1.-.-.-) (Cardiac peroxidase) (Inactive peroxidasin-like protein) (Polysomal ribonuclease 1) (PRM1) (Vascular peroxidase 2) Homo sapiens (Human) hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979] GO:0004519; GO:0004601; GO:0005615; GO:0005783; GO:0005886; GO:0006979; GO:0020037; GO:0042744; GO:0046872; GO:0140825 12986 XM_044309051.1 20 46 15 17 18 A1KZ92 1.65e-22 Probable oxidoreductase PXDNL (EC 1.-.-.-) (Cardiac peroxidase) (Inactive peroxidasin-like protein) (Polysomal ribonuclease 1) (PRM1) (Vascular peroxidase 2) Homo sapiens (Human) hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979] GO:0004519; GO:0004601; GO:0005615; GO:0005783; GO:0005886; GO:0006979; GO:0020037; GO:0042744; GO:0046872; GO:0140825 12987 XM_044328700.1 0 42 0 0 2 NA NA NA NA NA NA 12988 XM_029334901.2 69 13 37 53 53 NA NA NA NA NA NA 12989 XM_029332131.2 139 154 124 140 328 Q96P65 4.17e-23 Pyroglutamylated RF-amide peptide receptor (AQ27) (G-protein coupled receptor 103) (Orexigenic neuropeptide QRFP receptor) (SP9155) Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:0016020 12990 XR_006397865.1 46 30 0 16 39 Q86U44 1.89e-174 N6-adenosine-methyltransferase catalytic subunit (EC 2.1.1.348) (Methyltransferase-like protein 3) (hMETTL3) (N6-adenosine-methyltransferase 70 kDa subunit) (MT-A70) Homo sapiens (Human) adenosine to inosine editing [GO:0006382]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; circadian rhythm [GO:0007623]; dosage compensation by inactivation of X chromosome [GO:0009048]; endothelial to hematopoietic transition [GO:0098508]; forebrain radial glial cell differentiation [GO:0021861]; gliogenesis [GO:0042063]; innate immune response [GO:0045087]; mRNA catabolic process [GO:0006402]; mRNA destabilization [GO:0061157]; mRNA methylation [GO:0080009]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; oogenesis [GO:0048477]; positive regulation of cap-independent translational initiation [GO:1903679]; positive regulation of translation [GO:0045727]; primary miRNA processing [GO:0031053]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of meiotic cell cycle [GO:0051445]; regulation of T cell differentiation [GO:0045580]; RNA methylation [GO:0001510]; spermatogenesis [GO:0007283]; stem cell population maintenance [GO:0019827] GO:0000398; GO:0001510; GO:0001734; GO:0003729; GO:0005634; GO:0005654; GO:0005737; GO:0006382; GO:0006397; GO:0006402; GO:0006974; GO:0007283; GO:0007623; GO:0008168; GO:0008173; GO:0009048; GO:0016422; GO:0016607; GO:0019827; GO:0021861; GO:0031053; GO:0034644; GO:0036396; GO:0042063; GO:0045087; GO:0045580; GO:0045727; GO:0045746; GO:0046982; GO:0048477; GO:0051445; GO:0060339; GO:0061157; GO:0080009; GO:0098508; GO:1902036; GO:1903679; GO:1904047 12991 XM_044321700.1 619 268 211 0 180 B6CHA3 0 E3 ubiquitin-protein ligase UHRF1 (EC 2.3.2.27) (Nuclear zinc finger protein Np95) (XNp95) (RING-type E3 ubiquitin transferase UHRF1) (Ubiquitin-like PHD and RING finger domain-containing protein 1) (Ubiquitin-like-containing PHD and RING finger domains protein 1) Xenopus laevis (African clawed frog) cell cycle [GO:0007049]; chromatin organization [GO:0006325]; histone ubiquitination [GO:0016574]; maintenance of DNA methylation [GO:0010216]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein autoubiquitination [GO:0051865]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000122; GO:0000785; GO:0000791; GO:0000792; GO:0004842; GO:0005634; GO:0005657; GO:0006325; GO:0006511; GO:0007049; GO:0008270; GO:0010216; GO:0016574; GO:0035064; GO:0042393; GO:0044729; GO:0051865 12992 XM_029331717.2 340 73 126 16 0 Q5T1B0 4.68e-143 Axonemal dynein light chain domain-containing protein 1 Homo sapiens (Human) NA NA 12993 XM_029344975.2 96 1 80 0 16 Q8CIE2 9.93e-140 Zinc finger MIZ domain-containing protein 2 (PIAS-like protein Zimp7) Mus musculus (Mouse) positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0005634; GO:0005654; GO:0005739; GO:0006357; GO:0008270; GO:0030374; GO:0043596; GO:0045944 12994 XM_029327316.2 0 0 1 32 0 NA NA NA NA NA NA 12995 XM_044312511.1 9 1 19 91 2 NA NA NA NA NA NA 12996 XM_029347411.2 0 8 0 0 4 P70031 1.29e-33 Cholecystokinin receptor (CCK-XLR) Xenopus laevis (African clawed frog) NA GO:0004930; GO:0005886 12997 XM_044328930.1 13 24 0 0 48 NA NA NA NA NA NA 12998 XR_006392966.1 41 2 25 5 151 NA NA NA NA NA NA 12999 XM_044307972.1 5 22 21 68 11 O43422 6.21e-73 52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (Death-associated protein 4) (THAP domain-containing protein 0) (THAP domain-containing protein 12) Homo sapiens (Human) negative regulation of cell population proliferation [GO:0008285]; signal transduction [GO:0007165] GO:0003677; GO:0005634; GO:0007165; GO:0008285; GO:0046872; GO:0046983 13000 XM_029336364.2 242 336 135 367 404 NA NA NA NA NA NA 13001 XM_044328617.1 86 423 316 693 1129 A0A0R4IBK5 0 E3 ubiquitin-protein ligase rnf213-alpha (EC 2.3.2.27) (EC 3.6.4.-) (E3 ubiquitin-lipopolysaccharide ligase rnf213-alpha) (EC 2.3.2.-) (Mysterin-A) (Mysterin-alpha) (RING finger protein 213-A) (RING finger protein 213-alpha) Danio rerio (Zebrafish) (Brachydanio rerio) blood circulation [GO:0008015]; defense response to bacterium [GO:0042742]; immune system process [GO:0002376]; lipid droplet formation [GO:0140042]; lipid ubiquitination [GO:0120323]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein K63-linked ubiquitination [GO:0070534]; regulation of lipid metabolic process [GO:0019216]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]; xenophagy [GO:0098792] GO:0002040; GO:0002376; GO:0004842; GO:0005524; GO:0005730; GO:0005811; GO:0005829; GO:0006511; GO:0008015; GO:0016887; GO:0019216; GO:0042742; GO:0046872; GO:0061630; GO:0070534; GO:0098792; GO:0120323; GO:0140042; GO:2000051 13002 XM_044328617.1 86 423 316 693 1129 A0A0R4IBK5 3.03e-88 E3 ubiquitin-protein ligase rnf213-alpha (EC 2.3.2.27) (EC 3.6.4.-) (E3 ubiquitin-lipopolysaccharide ligase rnf213-alpha) (EC 2.3.2.-) (Mysterin-A) (Mysterin-alpha) (RING finger protein 213-A) (RING finger protein 213-alpha) Danio rerio (Zebrafish) (Brachydanio rerio) blood circulation [GO:0008015]; defense response to bacterium [GO:0042742]; immune system process [GO:0002376]; lipid droplet formation [GO:0140042]; lipid ubiquitination [GO:0120323]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein K63-linked ubiquitination [GO:0070534]; regulation of lipid metabolic process [GO:0019216]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]; xenophagy [GO:0098792] GO:0002040; GO:0002376; GO:0004842; GO:0005524; GO:0005730; GO:0005811; GO:0005829; GO:0006511; GO:0008015; GO:0016887; GO:0019216; GO:0042742; GO:0046872; GO:0061630; GO:0070534; GO:0098792; GO:0120323; GO:0140042; GO:2000051 13003 XM_044308461.1 0 0 61 120 75 NA NA NA NA NA NA 13004 XR_006396456.1 1 24 14 3 8 NA NA NA NA NA NA 13005 XM_029333330.2 1415 670 563 1026 966 Q8BP78 3.71e-77 Protein FRA10AC1 homolog Mus musculus (Mouse) dephosphorylation [GO:0016311] GO:0005634; GO:0016311; GO:0016791 13006 XM_044314946.1 14 25 0 12 5 NA NA NA NA NA NA 13007 XR_006395296.1 134 65 25 0 7 Q5BIM1 9.69e-53 Tripartite motif-containing protein 45 Bos taurus (Bovine) bone development [GO:0060348]; positive regulation of DNA-templated transcription [GO:0045893] GO:0000785; GO:0004842; GO:0005654; GO:0005829; GO:0008270; GO:0045171; GO:0045893; GO:0060348 13008 XM_029332362.2 406 199 240 245 525 Q587J7 3.77e-80 Putative ATP-dependent RNA helicase TDRD12 (EC 3.6.4.13) (ES cell-associated transcript 8 protein) (Tudor domain-containing protein 12) Homo sapiens (Human) cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; fertilization [GO:0009566]; male meiotic nuclear division [GO:0007140]; piRNA processing [GO:0034587]; RNA-mediated gene silencing [GO:0031047]; spermatogenesis [GO:0007283] GO:0003676; GO:0003724; GO:0005524; GO:0007140; GO:0007283; GO:0009566; GO:0016887; GO:0030154; GO:0031047; GO:0034587; GO:0043046; GO:1990923 13009 XM_044318217.1 3 17 0 20 11 NA NA NA NA NA NA 13010 XM_029328140.2 1792 1593 1058 1783 1815 Q148D5 0 Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial (EC 6.2.1.5) (ATP-specific succinyl-CoA synthetase subunit beta) (A-SCS) (Succinyl-CoA synthetase beta-A chain) (SCS-betaA) Bos taurus (Bovine) tricarboxylic acid cycle [GO:0006099] GO:0000287; GO:0004775; GO:0005524; GO:0005739; GO:0006099 13011 XM_044322613.1 1827 2011 1081 1609 1414 Q3SYV5 5.54e-58 Tetraspanin-33 (Tspan-33) Bos taurus (Bovine) NA GO:0005737; GO:0005886; GO:0005912 13012 XM_044328641.1 0 0 0 1 9 NA NA NA NA NA NA 13013 XM_029356411.2 7 9 7 18 5 NA NA NA NA NA NA 13014 XM_029328877.2 9710 8880 5669 8731 9435 Q3ZBG9 1.4e-104 Phospholipid scramblase 2 (PL scramblase 2) (Ca(2+)-dependent phospholipid scramblase 2) Bos taurus (Bovine) plasma membrane phospholipid scrambling [GO:0017121] GO:0005886; GO:0017121; GO:0017128; GO:0046872 13015 XR_006395742.1 178 151 100 189 64 NA NA NA NA NA NA 13016 XM_029324307.2 4611 2772 1723 10694 5496 NA NA NA NA NA NA 13017 XM_029335375.2 243 312 171 180 141 NA NA NA NA NA NA 13018 XM_029339833.2 198 223 76 181 202 NA NA NA NA NA NA 13019 XM_029327535.2 0 13 8 0 0 NA NA NA NA NA NA 13020 XM_029337556.2 1111 877 643 1026 904 Q04336 0 Uncharacterized protein YMR196W Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) oligosaccharide metabolic process [GO:0009311] GO:0004573; GO:0005737; GO:0009311 13021 XM_029358637.2 263 93 85 55 95 NA NA NA NA NA NA 13022 XM_029357921.2 0 12 13 16 319 Q91VN6 0 Probable ATP-dependent RNA helicase DDX41 (EC 3.6.4.13) (DEAD box protein 41) Mus musculus (Mouse) cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to interferon-beta [GO:0035458]; defense response to virus [GO:0051607]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000398; GO:0003677; GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005681; GO:0005783; GO:0008283; GO:0016887; GO:0030154; GO:0035458; GO:0045944; GO:0046872; GO:0051607; GO:0071013 13023 XR_006393336.1 157 214 225 173 213 NA NA NA NA NA NA 13024 XM_029349431.2 0 0 21 0 10 NA NA NA NA NA NA 13025 XM_044323548.1 215 371 233 158 208 NA NA NA NA NA NA 13026 XM_044307187.1 364 314 117 452 231 P51006 2.46e-130 Poly(A) polymerase type 3 (PAP) (EC 2.7.7.19) (Polynucleotide adenylyltransferase) Xenopus laevis (African clawed frog) mRNA processing [GO:0006397]; RNA polyadenylation [GO:0043631] GO:0003723; GO:0004652; GO:0005524; GO:0005634; GO:0006397; GO:0043631; GO:0046872 13027 XM_044310128.1 255 198 220 350 169 NA NA NA NA NA NA 13028 XR_006394808.1 3 0 2 4 7 NA NA NA NA NA NA 13029 XM_044323529.1 92 0 0 110 166 Q9HAC7 1.89e-165 Succinate--hydroxymethylglutarate CoA-transferase (EC 2.8.3.13) (Dermal papilla-derived protein 13) (SuccinylCoA:glutarate-CoA transferase) Homo sapiens (Human) NA GO:0005739; GO:0047369 13030 XM_029341636.2 185 62 107 98 150 Q8N5C6 0 S1 RNA-binding domain-containing protein 1 Homo sapiens (Human) nucleobase-containing compound metabolic process [GO:0006139]; translation [GO:0006412] GO:0003729; GO:0003735; GO:0006139; GO:0006412 13031 XM_044322526.1 7 76 13 98 50 NA NA NA NA NA NA 13032 XM_044315150.1 13 1 16 0 90 NA NA NA NA NA NA 13033 XM_029334585.2 0 0 9 8 18 NA NA NA NA NA NA 13034 XM_029331762.2 1022 784 777 1090 1213 NA NA NA NA NA NA 13035 XM_044313054.1 49 44 17 60 121 Q96AY4 1.78e-84 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13036 XM_044313054.1 49 44 17 60 121 Q96AY4 9.1e-81 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13037 XM_044313054.1 49 44 17 60 121 Q96AY4 9.46e-80 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13038 XM_044313054.1 49 44 17 60 121 Q96AY4 6.76e-79 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13039 XM_044313054.1 49 44 17 60 121 Q96AY4 5.31e-76 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13040 XM_044313054.1 49 44 17 60 121 Q96AY4 1.51e-73 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13041 XM_044313054.1 49 44 17 60 121 Q96AY4 5.48e-65 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13042 XR_006394264.1 11 4 43 9 189 NA NA NA NA NA NA 13043 XM_044321965.1 105 0 19 10 0 Q9HF54 1.87e-30 GTP-binding protein RHO1 Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii) actin filament organization [GO:0007015]; cortical cytoskeleton organization [GO:0030865]; establishment or maintenance of cell polarity [GO:0007163]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; small GTPase mediated signal transduction [GO:0007264] GO:0003924; GO:0005525; GO:0005856; GO:0005886; GO:0005938; GO:0007015; GO:0007163; GO:0007264; GO:0008360; GO:0019901; GO:0030865; GO:0031410; GO:0032956; GO:0042995 13044 XM_044321965.1 105 0 19 10 0 Q9HF54 1.87e-30 GTP-binding protein RHO1 Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii) actin filament organization [GO:0007015]; cortical cytoskeleton organization [GO:0030865]; establishment or maintenance of cell polarity [GO:0007163]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; small GTPase mediated signal transduction [GO:0007264] GO:0003924; GO:0005525; GO:0005856; GO:0005886; GO:0005938; GO:0007015; GO:0007163; GO:0007264; GO:0008360; GO:0019901; GO:0030865; GO:0031410; GO:0032956; GO:0042995 13045 XR_006397717.1 0 1 9 0 0 NA NA NA NA NA NA 13046 XM_044320449.1 260 6 12 103 79 NA NA NA NA NA NA 13047 XR_003827119.2 467 218 167 225 79 NA NA NA NA NA NA 13048 XM_044317091.1 2 16 1 5 10 Q9N126 1.14e-51 Retinol dehydrogenase 8 (EC 1.1.1.300) (Photoreceptor outer segment all-trans retinol dehydrogenase) Bos taurus (Bovine) estrogen biosynthetic process [GO:0006703]; response to stimulus [GO:0050896]; retinol metabolic process [GO:0042572]; visual perception [GO:0007601] GO:0004303; GO:0004745; GO:0005829; GO:0006703; GO:0007601; GO:0016491; GO:0042572; GO:0042622; GO:0050896; GO:0052650 13049 XM_029343779.2 8084 6789 4539 6711 6750 G3XCN6 8.84e-99 Glycine betaine/proline betaine transporter BetS Rhizobium meliloti (Ensifer meliloti) (Sinorhizobium meliloti) amino acid transport [GO:0006865]; sodium ion transport [GO:0006814] GO:0005886; GO:0006814; GO:0006865; GO:0022857 13050 XM_044319036.1 694 465 403 612 777 Q9Z277 3.16e-32 Tyrosine-protein kinase BAZ1B (EC 2.7.10.2) (Bromodomain adjacent to zinc finger domain protein 1B) (Williams syndrome transcription factor homolog) (Williams-Beuren syndrome chromosomal region 9 protein homolog) Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of mitotic chromosome condensation [GO:1905213]; positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription by RNA polymerase III [GO:0045945]; post-translational protein modification [GO:0043687]; regulation of response to DNA damage stimulus [GO:2001020] GO:0000793; GO:0004713; GO:0005524; GO:0005634; GO:0005654; GO:0005721; GO:0005730; GO:0006325; GO:0006338; GO:0006974; GO:0035066; GO:0035173; GO:0042393; GO:0043596; GO:0043687; GO:0045943; GO:0045944; GO:0045945; GO:0046872; GO:0090535; GO:0110016; GO:0140801; GO:1905213; GO:2001020 13051 XM_029341981.2 190 0 512 302 81 Q9CYL5 5.67e-33 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Mus musculus (Mouse) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070374 13052 XM_029341981.2 190 0 512 302 81 Q9CYL5 1.7e-23 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Mus musculus (Mouse) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070374 13053 XM_029337183.2 58 83 0 160 57 NA NA NA NA NA NA 13054 XM_044323981.1 151 572 112 225 239 P35546 3.08e-81 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; anatomical structure morphogenesis [GO:0009653]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006919; GO:0007156; GO:0007158; GO:0007169; GO:0007399; GO:0009410; GO:0009653; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030182; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0098797; GO:2001241 13055 XM_029343219.2 961 635 325 629 456 NA NA NA NA NA NA 13056 XM_029336881.2 1548 1005 760 1395 930 A4FU69 1.33e-123 EF-hand calcium-binding domain-containing protein 5 Homo sapiens (Human) NA GO:0005509 13057 XM_029336881.2 1548 1005 760 1395 930 A4FU69 2.9e-43 EF-hand calcium-binding domain-containing protein 5 Homo sapiens (Human) NA GO:0005509 13058 XM_044314098.1 83 63 68 206 145 Q94K49 6.99e-44 Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1 (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) epigenetic regulation of gene expression [GO:0040029] GO:0003682; GO:0004518; GO:0005634; GO:0035098; GO:0035102; GO:0040029; GO:0046872 13059 XM_029355991.2 316 35 6 238 104 NA NA NA NA NA NA 13060 XM_044328379.1 21 0 17 0 1 NA NA NA NA NA NA 13061 XM_029330406.2 200 175 79 61 43 NA NA NA NA NA NA 13062 XR_006391275.1 860 393 529 1022 926 Q9NZJ4 0 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 13063 XR_006391275.1 860 393 529 1022 926 Q9NZJ4 0 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 13064 XR_006391275.1 860 393 529 1022 926 Q9NZJ4 4.6e-47 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 13065 XR_006391275.1 860 393 529 1022 926 Q9NZJ4 3.55e-43 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 13066 XR_006391275.1 860 393 529 1022 926 Q9NZJ4 2.32e-40 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 13067 XR_006391275.1 860 393 529 1022 926 Q9NZJ4 2.32e-34 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 13068 XM_044314441.1 1130 304 244 732 121 P59046 8.7e-42 NACHT, LRR and PYD domains-containing protein 12 (Monarch-1) (PYRIN-containing APAF1-like protein 7) (Regulated by nitric oxide) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cellular response to cytokine stimulus [GO:0071345]; dendritic cell migration [GO:0036336]; ERK1 and ERK2 cascade [GO:0070371]; negative regulation of cytokine production [GO:0001818]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of signal transduction [GO:0009968]; negative regulation of Toll signaling pathway [GO:0045751]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of inflammatory response [GO:0050727]; regulation of interleukin-18 production [GO:0032661]; signal transduction [GO:0007165] GO:0001818; GO:0005524; GO:0005737; GO:0005829; GO:0006919; GO:0007165; GO:0008656; GO:0009968; GO:0031953; GO:0032088; GO:0032661; GO:0032692; GO:0032715; GO:0032731; GO:0036336; GO:0038061; GO:0043122; GO:0043124; GO:0043281; GO:0045345; GO:0045751; GO:0050727; GO:0050728; GO:0050729; GO:0070371; GO:0070373; GO:0071345; GO:1901223; GO:1901224 13069 XR_006396549.1 56 104 31 23 67 NA NA NA NA NA NA 13070 XM_029338972.2 19 100 0 55 54 NA NA NA NA NA NA 13071 XR_006398026.1 6 0 10 5 28 NA NA NA NA NA NA 13072 XR_006398029.1 0 0 0 0 62 NA NA NA NA NA NA 13073 XM_029358178.2 186 305 32 133 116 Q14149 5.8e-177 MORC family CW-type zinc finger protein 3 (Nuclear matrix protein 2) (Zinc finger CW-type coiled-coil domain protein 3) Homo sapiens (Human) innate immune response [GO:0045087]; maintenance of protein location in nucleus [GO:0051457]; negative regulation of fibroblast proliferation [GO:0048147]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cellular senescence [GO:2000774]; post-embryonic development [GO:0009791]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821] GO:0003723; GO:0005634; GO:0005654; GO:0005694; GO:0006468; GO:0008270; GO:0009791; GO:0016363; GO:0016605; GO:0016887; GO:0018105; GO:0035064; GO:0045087; GO:0048147; GO:0050821; GO:0051457; GO:2000774 13074 XM_044328907.1 38 32 46 80 19 O14649 8.15e-36 Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1) (Two pore K(+) channel KT3.1) Homo sapiens (Human) brain development [GO:0007420]; cellular response to hypoxia [GO:0071456]; cellular response to zinc ion [GO:0071294]; chemical synaptic transmission [GO:0007268]; cochlea development [GO:0090102]; ion transmembrane transport [GO:0034220]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; positive regulation of voltage-gated potassium channel activity [GO:1903818]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of resting membrane potential [GO:0060075]; response to xenobiotic stimulus [GO:0009410]; stabilization of membrane potential [GO:0030322] GO:0005216; GO:0005252; GO:0005267; GO:0005886; GO:0006813; GO:0007268; GO:0007420; GO:0008022; GO:0009410; GO:0015271; GO:0022841; GO:0030322; GO:0034220; GO:0044548; GO:0045202; GO:0051481; GO:0060075; GO:0071294; GO:0071456; GO:0071805; GO:0090102; GO:1903818 13075 XM_029331249.2 14 40 13 20 5 Q8GW72 6.34e-32 Alpha-L-fucosidase 1 (EC 3.2.1.51) (Alpha-1,3/4-fucosidase) (AtFUC1) (Alpha-L-fucoside fucohydrolase) Arabidopsis thaliana (Mouse-ear cress) fucose metabolic process [GO:0006004]; glycoprotein catabolic process [GO:0006516]; glycoside catabolic process [GO:0016139] GO:0000325; GO:0004560; GO:0005764; GO:0006004; GO:0006516; GO:0016139; GO:0048046; GO:0099503 13076 XM_029336919.2 143 60 31 114 66 NA NA NA NA NA NA 13077 XM_029328863.2 4139 3957 3096 3809 4240 P18433 9.63e-170 Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (EC 3.1.3.48) Homo sapiens (Human) insulin receptor signaling pathway [GO:0008286]; integrin-mediated signaling pathway [GO:0007229]; modulation of chemical synaptic transmission [GO:0050804]; protein dephosphorylation [GO:0006470]; protein phosphorylation [GO:0006468]; regulation of focal adhesion assembly [GO:0051893] GO:0004725; GO:0005001; GO:0005886; GO:0005925; GO:0006468; GO:0006470; GO:0007229; GO:0008286; GO:0016020; GO:0043235; GO:0050804; GO:0051893; GO:0070062; GO:0097060; GO:0098685 13078 XR_006392822.1 1 0 0 0 7 NA NA NA NA NA NA 13079 XM_029341005.2 178 207 385 259 162 NA NA NA NA NA NA 13080 XM_044328648.1 804 883 693 684 762 Q962X9 2.66e-93 Protein BUD31 homolog (Protein G10 homolog) Branchiostoma belcheri (Amphioxus) NA GO:0005634 13081 XM_044308903.1 14 0 0 3 0 NA NA NA NA NA NA 13082 XM_029335179.2 172 242 95 208 119 NA NA NA NA NA NA 13083 XM_044321903.1 1112 231 735 866 900 Q9ULI1 4.49e-68 NACHT and WD repeat domain-containing protein 2 (Leucine-rich repeat and WD repeat-containing protein KIAA1239) Homo sapiens (Human) NA NA 13084 XM_029358042.2 112 72 98 138 0 Q91WD4 3.16e-100 UPF0415 protein C7orf25 homolog Mus musculus (Mouse) NA NA 13085 XM_029346102.2 1994 1965 1210 1449 1751 NA NA NA NA NA NA 13086 XM_029347995.2 6 0 5 7 21 NA NA NA NA NA NA 13087 XM_044314240.1 0 37 0 0 0 NA NA NA NA NA NA 13088 XM_044308073.1 0 102 56 0 0 Q8IV61 1.25e-134 Ras guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1) Homo sapiens (Human) MAPK cascade [GO:0000165]; positive regulation of GTPase activity [GO:0043547]; Ras protein signal transduction [GO:0007265]; small GTPase mediated signal transduction [GO:0007264] GO:0000165; GO:0005085; GO:0005096; GO:0005509; GO:0005886; GO:0007264; GO:0007265; GO:0019900; GO:0019992; GO:0031267; GO:0032045; GO:0043547; GO:0048471 13089 XR_006391744.1 3 0 10 14 90 NA NA NA NA NA NA 13090 XM_044323429.1 160 141 167 220 1101 NA NA NA NA NA NA 13091 XM_044315376.1 0 0 0 0 8 Q09575 1.58e-27 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 13092 XM_029340187.2 0 0 11 4 0 NA NA NA NA NA NA 13093 XM_029339647.2 324 234 138 369 265 P29348 1.25e-84 Guanine nucleotide-binding protein G(t) subunit alpha-3 (Gustducin alpha-3 chain) Rattus norvegicus (Rat) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; G protein-coupled receptor signaling pathway [GO:0007186]; response to nicotine [GO:0035094]; sensory perception of bitter taste [GO:0050913]; sensory perception of sweet taste [GO:0050916]; sensory perception of taste [GO:0050909]; sensory perception of umami taste [GO:0050917]; visual perception [GO:0007601] GO:0001580; GO:0001664; GO:0001669; GO:0001750; GO:0001917; GO:0003924; GO:0005525; GO:0005737; GO:0005834; GO:0005886; GO:0005930; GO:0007186; GO:0007188; GO:0007601; GO:0016324; GO:0031683; GO:0032991; GO:0035094; GO:0046872; GO:0050909; GO:0050913; GO:0050916; GO:0050917 13094 XM_044320124.1 25 9 13 26 27 NA NA NA NA NA NA 13095 XM_029329839.2 10 1 0 0 2 Q4I963 1.57e-22 Cofilin (Actin-depolymerizing factor 1) Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1) (Wheat head blight fungus) (Fusarium graminearum) actin filament depolymerization [GO:0030042]; cell cycle [GO:0007049]; cell division [GO:0051301] GO:0003779; GO:0005737; GO:0007049; GO:0015629; GO:0016363; GO:0030042; GO:0051301 13096 XR_006395453.1 915 919 537 995 995 NA NA NA NA NA NA 13097 XM_044321260.1 11 0 15 4 52 NA NA NA NA NA NA 13098 XM_044327895.1 38 75 52 153 67 NA NA NA NA NA NA 13099 XM_029342200.2 927 389 338 398 469 A7YWD2 0 Importin-13 (Imp13) Bos taurus (Bovine) protein import into nucleus [GO:0006606] GO:0005634; GO:0005737; GO:0006606; GO:0031267 13100 XM_029339516.2 1013 81 25 25 22 NA NA NA NA NA NA 13101 XM_029357784.2 5 7 7 7 24 P16066 0 Atrial natriuretic peptide receptor 1 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type A) (ANP-A) (ANPR-A) (NPR-A) (Guanylate cyclase A) (GC-A) Homo sapiens (Human) blood vessel diameter maintenance [GO:0097746]; body fluid secretion [GO:0007589]; cell surface receptor signaling pathway [GO:0007166]; cGMP biosynthetic process [GO:0006182]; cGMP-mediated signaling [GO:0019934]; dopamine metabolic process [GO:0042417]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell growth [GO:0030308]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of cGMP-mediated signaling [GO:0010753]; positive regulation of renal sodium excretion [GO:0035815]; positive regulation of urine volume [GO:0035810]; protein phosphorylation [GO:0006468]; receptor guanylyl cyclase signaling pathway [GO:0007168]; regulation of blood pressure [GO:0008217]; regulation of vascular permeability [GO:0043114]; signal transduction [GO:0007165] GO:0001653; GO:0004383; GO:0004672; GO:0005524; GO:0005525; GO:0005886; GO:0006182; GO:0006468; GO:0007165; GO:0007166; GO:0007168; GO:0007589; GO:0008217; GO:0008528; GO:0010753; GO:0016525; GO:0016941; GO:0017046; GO:0019934; GO:0030308; GO:0035810; GO:0035815; GO:0042417; GO:0042562; GO:0043114; GO:0043235; GO:0048662; GO:0097746; GO:1990620 13102 XM_029341809.2 72 64 46 70 94 NA NA NA NA NA NA 13103 XM_029356199.2 20 3 5 2 22 Q96A58 1.41e-36 Ras-related and estrogen-regulated growth inhibitor (EC 3.6.5.2) Homo sapiens (Human) negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; Ras protein signal transduction [GO:0007265]; response to hormone [GO:0009725]; small GTPase mediated signal transduction [GO:0007264] GO:0001650; GO:0003924; GO:0003925; GO:0005525; GO:0005634; GO:0005654; GO:0005829; GO:0005886; GO:0007264; GO:0007265; GO:0008285; GO:0009725; GO:0019003; GO:0030308; GO:0030331 13104 XM_044320415.1 0 51 0 0 0 NA NA NA NA NA NA 13105 XM_029324945.2 7 0 0 0 24 NA NA NA NA NA NA 13106 XR_006395378.1 42 53 47 317 106 NA NA NA NA NA NA 13107 XR_003824359.2 563 311 143 367 200 NA NA NA NA NA NA 13108 XM_044307162.1 434 208 304 472 592 Q7RTR2 6.96e-35 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 13109 XM_044307162.1 434 208 304 472 592 Q7RTR2 2.12e-30 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 13110 XM_044307162.1 434 208 304 472 592 Q7RTR2 1.3e-28 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 13111 XM_044307162.1 434 208 304 472 592 Q7RTR2 2.24e-27 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 13112 XM_044307162.1 434 208 304 472 592 Q7RTR2 4.48e-25 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 13113 XR_006392128.1 10 0 0 0 14 NA NA NA NA NA NA 13114 XM_029330000.2 0 7 0 0 0 Q9TTT5 1.59e-89 Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3) Oryctolagus cuniculus (Rabbit) protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0008076; GO:0030425; GO:0034765; GO:0042383; GO:0046872; GO:0051260 13115 XM_044319492.1 6 8 9 0 7 NA NA NA NA NA NA 13116 XM_044323837.1 59 33 28 30 31 NA NA NA NA NA NA 13117 XM_029341697.2 14 8 10 17 0 Q921Y2 5.78e-72 U3 small nucleolar ribonucleoprotein protein IMP3 (U3 snoRNP protein IMP3) Mus musculus (Mouse) ribosomal small subunit biogenesis [GO:0042274]; rRNA processing [GO:0006364] GO:0003735; GO:0005634; GO:0005654; GO:0005730; GO:0006364; GO:0015935; GO:0019843; GO:0030515; GO:0030684; GO:0032040; GO:0034457; GO:0042274 13118 XM_029356758.2 46 0 0 0 0 Q8NHP1 3.52e-88 Aflatoxin B1 aldehyde reductase member 4 (EC 1.-.-.-) (AFB1 aldehyde reductase 3) (AFB1-AR 3) (Aldoketoreductase 7-like) Homo sapiens (Human) NA GO:0004033; GO:0005737; GO:0005829; GO:0070062 13119 XM_029356758.2 46 0 0 0 0 Q8NHP1 2.62e-46 Aflatoxin B1 aldehyde reductase member 4 (EC 1.-.-.-) (AFB1 aldehyde reductase 3) (AFB1-AR 3) (Aldoketoreductase 7-like) Homo sapiens (Human) NA GO:0004033; GO:0005737; GO:0005829; GO:0070062 13120 XM_044323996.1 27 274 42 0 14 NA NA NA NA NA NA 13121 XM_029356253.2 133 86 66 102 177 NA NA NA NA NA NA 13122 XM_044317892.1 42 10 62 14 107 NA NA NA NA NA NA 13123 XM_029355439.2 3563 2496 1526 2234 1570 P62494 2.29e-88 Ras-related protein Rab-11A (Rab-11) (EC 3.6.5.2) (24KG) Rattus norvegicus (Rat) amyloid-beta clearance by transcytosis [GO:0150093]; astral microtubule organization [GO:0030953]; establishment of protein localization to membrane [GO:0090150]; establishment of protein localization to organelle [GO:0072594]; establishment of vesicle localization [GO:0051650]; exocytosis [GO:0006887]; exosomal secretion [GO:1990182]; intracellular cholesterol transport [GO:0032367]; melanosome transport [GO:0032402]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly [GO:0090307]; multivesicular body assembly [GO:0036258]; neuron projection development [GO:0031175]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; positive regulation of axon extension [GO:0045773]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; regulation of cytokinesis [GO:0032465]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multivesicular body size [GO:0010796]; regulation of protein transport [GO:0051223]; regulation of vesicle-mediated transport [GO:0060627]; vesicle-mediated transport [GO:0016192]; vesicle-mediated transport in synapse [GO:0099003] GO:0000922; GO:0003924; GO:0003925; GO:0005525; GO:0005737; GO:0005768; GO:0005771; GO:0005794; GO:0005802; GO:0005813; GO:0005814; GO:0005829; GO:0006887; GO:0007080; GO:0008017; GO:0010634; GO:0010796; GO:0010971; GO:0016020; GO:0016192; GO:0030133; GO:0030424; GO:0030953; GO:0031175; GO:0031410; GO:0031489; GO:0031982; GO:0032154; GO:0032367; GO:0032402; GO:0032465; GO:0032991; GO:0034394; GO:0036258; GO:0045335; GO:0045773; GO:0048169; GO:0048471; GO:0051223; GO:0051650; GO:0055037; GO:0055038; GO:0060627; GO:0070062; GO:0072594; GO:0072659; GO:0090150; GO:0090307; GO:0098685; GO:0098837; GO:0098887; GO:0098978; GO:0099003; GO:0150093; GO:1903078; GO:1990182 13124 XM_029335628.2 714 587 376 1105 1255 Q8N6T3 1.07e-70 ADP-ribosylation factor GTPase-activating protein 1 (ARF GAP 1) (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase-activating protein) Homo sapiens (Human) protein transport [GO:0015031]; regulation of ARF protein signal transduction [GO:0032012]; regulation of endocytosis [GO:0030100]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0005096; GO:0005829; GO:0015031; GO:0016192; GO:0030100; GO:0032012; GO:0045202; GO:0046872 13125 XM_029335673.2 204 97 113 162 224 P59913 4.3e-97 Protein-L-isoaspartate O-methyltransferase domain-containing protein 1 Mus musculus (Mouse) NA GO:0004719; GO:0005737; GO:0016020 13126 XR_006394366.1 28 0 4 0 20 NA NA NA NA NA NA 13127 XM_029358658.2 0 0 0 6 0 NA NA NA NA NA NA 13128 XM_029355294.2 9441 11898 5885 7988 7233 Q8JGR4 7.64e-56 60S ribosomal protein L24 Danio rerio (Zebrafish) (Brachydanio rerio) chordate embryonic development [GO:0043009]; cytoplasmic translation [GO:0002181] GO:0002181; GO:0003729; GO:0003735; GO:0022625; GO:0043009 13129 XR_006396504.1 24 53 48 47 676 NA NA NA NA NA NA 13130 XR_003827988.2 66 15 30 35 59 NA NA NA NA NA NA 13131 XR_006391569.1 9 11 2 2 11 NA NA NA NA NA NA 13132 XM_029349382.2 365 196 265 442 364 Q05973 0 Sodium channel protein 1 brain (Sodium channel protein I brain) Heterololigo bleekeri (Spear squid) (Loligo bleekeri) regulation of ion transmembrane transport [GO:0034765] GO:0001518; GO:0005244; GO:0005248; GO:0034765 13133 XM_029333268.2 0 0 6 0 12 NA NA NA NA NA NA 13134 XM_029332389.2 632 651 501 614 608 A7S6Y0 1.9e-71 Protein SYS1 homolog Nematostella vectensis (Starlet sea anemone) Golgi to endosome transport [GO:0006895]; Golgi to plasma membrane protein transport [GO:0043001]; protein localization to Golgi apparatus [GO:0034067] GO:0000139; GO:0005802; GO:0005829; GO:0006895; GO:0034067; GO:0043001 13135 XR_003824076.2 10 9 6 19 0 NA NA NA NA NA NA 13136 XR_003824586.2 101 49 59 33 60 NA NA NA NA NA NA 13137 XR_006394065.1 34 3 18 8 9 NA NA NA NA NA NA 13138 XM_029336263.2 18 1 16 5 22 NA NA NA NA NA NA 13139 XM_044326465.1 43 79 20 92 84 Q6P7Q4 2.26e-64 Lactoylglutathione lyase (EC 4.4.1.5) (Aldoketomutase) (Glyoxalase I) (Glx I) (Ketone-aldehyde mutase) (Methylglyoxalase) (S-D-lactoylglutathione methylglyoxal lyase) Rattus norvegicus (Rat) carbohydrate metabolic process [GO:0005975]; glutathione metabolic process [GO:0006749]; methylglyoxal metabolic process [GO:0009438]; negative regulation of apoptotic process [GO:0043066]; osteoclast differentiation [GO:0030316]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0004462; GO:0005654; GO:0005829; GO:0005886; GO:0005975; GO:0006357; GO:0006749; GO:0008270; GO:0009438; GO:0030316; GO:0043066 13140 XM_044324949.1 56 0 48 24 176 NA NA NA NA NA NA 13141 XM_029342763.2 119 0 147 116 72 P48547 1.44e-89 Potassium voltage-gated channel subfamily C member 1 (NGK2) (Voltage-gated potassium channel subunit Kv3.1) (Voltage-gated potassium channel subunit Kv4) Homo sapiens (Human) cellular response to xenobiotic stimulus [GO:0071466]; cerebellum development [GO:0021549]; corpus callosum development [GO:0022038]; globus pallidus development [GO:0021759]; optic nerve development [GO:0021554]; positive regulation of voltage-gated potassium channel activity [GO:1903818]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; protein tetramerization [GO:0051262]; response to amine [GO:0014075]; response to auditory stimulus [GO:0010996]; response to fibroblast growth factor [GO:0071774]; response to light intensity [GO:0009642]; response to nerve growth factor [GO:1990089]; response to potassium ion [GO:0035864]; response to toxic substance [GO:0009636] GO:0005249; GO:0005251; GO:0005886; GO:0006813; GO:0008076; GO:0009636; GO:0009642; GO:0009986; GO:0010996; GO:0014075; GO:0016020; GO:0019894; GO:0021549; GO:0021554; GO:0021759; GO:0022038; GO:0030424; GO:0030673; GO:0032590; GO:0032809; GO:0035864; GO:0042734; GO:0044305; GO:0044325; GO:0045211; GO:0051260; GO:0051262; GO:0071466; GO:0071774; GO:0071805; GO:0099508; GO:1903818; GO:1990089 13142 XM_029339141.2 245 102 162 301 29 Q568B7 1.94e-153 Glycosyltransferase-like domain-containing protein 1 Danio rerio (Zebrafish) (Brachydanio rerio) central nervous system development [GO:0007417] GO:0007417; GO:0016757 13143 XM_044328860.1 0 0 0 26 2 NA NA NA NA NA NA 13144 XM_044325253.1 125 243 187 3 151 NA NA NA NA NA NA 13145 XM_044309841.1 9 11 41 17 9 NA NA NA NA NA NA 13146 XM_044319233.1 90 25 58 34 56 Q6GNV7 4.04e-83 Solute carrier family 49 member 4 homolog (Disrupted in renal carcinoma protein 2 homolog) Xenopus laevis (African clawed frog) NA GO:0005765; GO:0022857 13147 XR_006391971.1 162 11 4 200 234 NA NA NA NA NA NA 13148 XM_029332277.2 348 224 218 309 308 O00750 0 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (PI3K-C2-beta) (PtdIns-3-kinase C2 subunit beta) (EC 2.7.1.137) (EC 2.7.1.154) (C2-PI3K) (Phosphoinositide 3-kinase-C2-beta) Homo sapiens (Human) autophagosome organization [GO:1905037]; cell migration [GO:0016477]; cellular response to starvation [GO:0009267]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol phosphate biosynthetic process [GO:0046854]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; phosphatidylinositol-mediated signaling [GO:0048015]; protein kinase B signaling [GO:0043491] GO:0001727; GO:0005524; GO:0005654; GO:0005737; GO:0005783; GO:0005829; GO:0005886; GO:0005942; GO:0009267; GO:0014065; GO:0016020; GO:0016303; GO:0016477; GO:0030139; GO:0035005; GO:0035091; GO:0036092; GO:0043231; GO:0043491; GO:0046854; GO:0048015; GO:0052742; GO:1905037 13149 XM_044326847.1 0 4 38 14 20 NA NA NA NA NA NA 13150 XM_044326997.1 912 549 480 879 827 Q3UQ28 2.3e-27 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 13151 XM_044326997.1 912 549 480 879 827 Q3UQ28 2.3e-27 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 13152 XM_044320035.1 131 0 100 33 0 Q5U243 2.34e-137 CAP-Gly domain-containing linker protein 3 (Cytoplasmic linker protein 170-related 59 kDa protein) (CLIP-170-related 59 kDa protein) (CLIPR-59) Xenopus laevis (African clawed frog) NA GO:0005795 13153 XR_006394135.1 0 20 0 36 19 NA NA NA NA NA NA 13154 XR_006391492.1 3 284 1 0 1 NA NA NA NA NA NA 13155 XM_029357780.2 10 79 0 39 8 NA NA NA NA NA NA 13156 XM_044322920.1 161 101 146 171 181 Q9Y5W9 5.56e-24 Sorting nexin-11 Homo sapiens (Human) intracellular protein transport [GO:0006886]; vesicle organization [GO:0016050] GO:0005768; GO:0006886; GO:0016020; GO:0016050; GO:1901981 13157 XM_029349411.2 0 2 6 0 12 NA NA NA NA NA NA 13158 XM_029330306.2 238 79 86 189 167 NA NA NA NA NA NA 13159 XM_044317716.1 5795 4526 7827 5969 6993 Q9H4G4 1.79e-25 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Homo sapiens (Human) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070062; GO:0070374 13160 XM_044307151.1 373 52 212 241 383 Q9UHC1 1.54e-88 DNA mismatch repair protein Mlh3 (MutL protein homolog 3) Homo sapiens (Human) female meiosis I [GO:0007144]; male meiotic nuclear division [GO:0007140]; mismatch repair [GO:0006298]; protein localization [GO:0008104]; reciprocal meiotic recombination [GO:0007131]; synaptonemal complex assembly [GO:0007130] GO:0000795; GO:0001673; GO:0003682; GO:0003696; GO:0005524; GO:0005634; GO:0005654; GO:0005712; GO:0006298; GO:0007130; GO:0007131; GO:0007140; GO:0007144; GO:0008104; GO:0016887; GO:0019237; GO:0030983; GO:0032300; GO:0140664 13161 XM_044307151.1 373 52 212 241 383 Q9UHC1 6.6e-57 DNA mismatch repair protein Mlh3 (MutL protein homolog 3) Homo sapiens (Human) female meiosis I [GO:0007144]; male meiotic nuclear division [GO:0007140]; mismatch repair [GO:0006298]; protein localization [GO:0008104]; reciprocal meiotic recombination [GO:0007131]; synaptonemal complex assembly [GO:0007130] GO:0000795; GO:0001673; GO:0003682; GO:0003696; GO:0005524; GO:0005634; GO:0005654; GO:0005712; GO:0006298; GO:0007130; GO:0007131; GO:0007140; GO:0007144; GO:0008104; GO:0016887; GO:0019237; GO:0030983; GO:0032300; GO:0140664 13162 XM_029340617.2 6989 5499 4418 7083 6676 P82471 0 Guanine nucleotide-binding protein G(q) subunit alpha (Guanine nucleotide-binding protein alpha-q) Rattus norvegicus (Rat) action potential [GO:0001508]; activation of phospholipase C activity [GO:0007202]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cranial skeletal system development [GO:1904888]; developmental pigmentation [GO:0048066]; embryonic digit morphogenesis [GO:0042733]; endothelin receptor signaling pathway [GO:0086100]; forebrain neuron development [GO:0021884]; G protein-coupled receptor signaling pathway [GO:0007186]; glutamate receptor signaling pathway [GO:0007215]; heart development [GO:0007507]; ion channel modulating, G protein-coupled receptor signaling pathway [GO:0099105]; ligand-gated ion channel signaling pathway [GO:1990806]; maternal behavior [GO:0042711]; multicellular organism aging [GO:0010259]; negative regulation of apoptotic process [GO:0043066]; negative regulation of potassium ion transport [GO:0043267]; negative regulation of protein kinase activity [GO:0006469]; neuron remodeling [GO:0016322]; phospholipase C-activating dopamine receptor signaling pathway [GO:0060158]; phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway [GO:0007207]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of insulin secretion [GO:0032024]; positive regulation of smooth muscle cell proliferation [GO:0048661]; post-embryonic development [GO:0009791]; protein stabilization [GO:0050821]; regulation of blood pressure [GO:0008217]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of melanocyte differentiation [GO:0045634]; regulation of platelet activation [GO:0010543]; skeletal system development [GO:0001501] GO:0001501; GO:0001508; GO:0001664; GO:0003924; GO:0003925; GO:0005096; GO:0005246; GO:0005525; GO:0005794; GO:0005829; GO:0005834; GO:0005886; GO:0005901; GO:0006469; GO:0007186; GO:0007188; GO:0007189; GO:0007200; GO:0007202; GO:0007207; GO:0007215; GO:0007507; GO:0008217; GO:0009791; GO:0010259; GO:0010543; GO:0016004; GO:0016020; GO:0016322; GO:0021884; GO:0030425; GO:0031683; GO:0031965; GO:0032024; GO:0042711; GO:0042733; GO:0043066; GO:0043267; GO:0044297; GO:0044877; GO:0045202; GO:0045634; GO:0046872; GO:0047391; GO:0048066; GO:0048661; GO:0050821; GO:0060158; GO:0060828; GO:0086100; GO:0099103; GO:0099105; GO:0099107; GO:1904888; GO:1990806 13163 XM_029332419.2 117 134 146 82 319 NA NA NA NA NA NA 13164 XM_044318110.1 167 80 85 92 108 NA NA NA NA NA NA 13165 XM_029333818.2 0 58 0 0 0 P97363 0 Serine palmitoyltransferase 2 (EC 2.3.1.50) (Long chain base biosynthesis protein 2) (LCB 2) (Long chain base biosynthesis protein 2a) (LCB2a) (Serine-palmitoyl-CoA transferase 2) (SPT 2) Mus musculus (Mouse) adipose tissue development [GO:0060612]; ceramide biosynthetic process [GO:0046513]; lipophagy [GO:0061724]; positive regulation of lipophagy [GO:1904504]; sphinganine biosynthetic process [GO:0046511]; sphingolipid biosynthetic process [GO:0030148]; sphingomyelin biosynthetic process [GO:0006686]; sphingosine biosynthetic process [GO:0046512] GO:0004758; GO:0005739; GO:0005789; GO:0006686; GO:0017059; GO:0030148; GO:0030170; GO:0046511; GO:0046512; GO:0046513; GO:0060612; GO:0061724; GO:1904504 13166 XM_044319318.1 0 0 1 9 8 P30974 6.98e-33 Tachykinin-like peptides receptor 86C (NKD) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; inter-male aggressive behavior [GO:0002121]; neuropeptide signaling pathway [GO:0007218]; tachykinin receptor signaling pathway [GO:0007217] GO:0002121; GO:0004995; GO:0005886; GO:0007186; GO:0007217; GO:0007218; GO:0008188; GO:0016020 13167 XM_029333665.2 32 0 0 0 0 A0JPI9 2.77e-49 Leucine-rich repeat-containing protein 74A (Leucine-rich repeat-containing protein 74) Rattus norvegicus (Rat) NA NA 13168 XM_044323602.1 104 8 44 33 74 B8JK39 1.15e-103 Integrin alpha-9 Mus musculus (Mouse) cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; neutrophil chemotaxis [GO:0030593]; wound healing [GO:0042060] GO:0005178; GO:0005518; GO:0007155; GO:0007160; GO:0007229; GO:0008305; GO:0009897; GO:0009925; GO:0016020; GO:0030593; GO:0033627; GO:0034679; GO:0042060; GO:0043236; GO:0046872; GO:0050900; GO:0098609 13169 XM_044309881.1 7 6 3 0 0 Q09575 2.42e-22 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 13170 XM_029335962.2 157 163 108 137 87 Q28GJ2 4.36e-106 Ester hydrolase C11orf54 homolog (EC 3.1.-.-) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005634; GO:0016787; GO:0046872 13171 XM_029326836.2 442 515 250 314 450 D3YXG0 3.71e-84 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 13172 XM_029326836.2 442 515 250 314 450 D3YXG0 8.79e-72 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 13173 XM_044310517.1 34 4 27 57 51 NA NA NA NA NA NA 13174 XM_029352104.2 192 77 97 327 219 Q8BHA0 6.87e-38 INO80 complex subunit C Mus musculus (Mouse) chromatin remodeling [GO:0006338]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of telomere maintenance in response to DNA damage [GO:1904507]; regulation of cell cycle [GO:0051726]; regulation of chromosome organization [GO:0033044]; regulation of DNA repair [GO:0006282]; regulation of DNA replication [GO:0006275]; regulation of DNA strand elongation [GO:0060382]; regulation of embryonic development [GO:0045995]; telomere maintenance [GO:0000723] GO:0000723; GO:0006275; GO:0006281; GO:0006282; GO:0006310; GO:0006338; GO:0031011; GO:0033044; GO:0045739; GO:0045893; GO:0045995; GO:0051726; GO:0060382; GO:0071339; GO:1904507 13175 XM_029338393.2 1510 1920 1217 969 923 NA NA NA NA NA NA 13176 XM_029351880.2 608 509 273 749 522 Q18120 1.55e-25 TWiK family of potassium channels protein 18 Caenorhabditis elegans locomotion [GO:0040011]; muscle contraction [GO:0006936]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; stabilization of membrane potential [GO:0030322] GO:0005886; GO:0006813; GO:0006936; GO:0015271; GO:0016020; GO:0022841; GO:0030322; GO:0040011; GO:0071805 13177 XM_029342765.2 68 0 0 3 37 P17972 3.41e-114 Potassium voltage-gated channel protein Shaw (Shaw2) Drosophila melanogaster (Fruit fly) potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765]; sleep [GO:0030431] GO:0005249; GO:0005251; GO:0005886; GO:0006813; GO:0008076; GO:0016020; GO:0022843; GO:0030424; GO:0030431; GO:0032590; GO:0032809; GO:0034765; GO:0051260; GO:0071805 13178 XM_044308842.1 0 0 0 11 0 NA NA NA NA NA NA 13179 XM_029323981.2 1604 1324 893 1262 1289 O55236 0 mRNA-capping enzyme (HCE) (MCE1) [Includes: mRNA 5'-triphosphate monophosphatase (EC 3.6.1.74) (mRNA 5'-phosphatase); mRNA guanylyltransferase (EC 2.7.7.50) (GTP--RNA guanylyltransferase) (GTase)] Mus musculus (Mouse) 7-methylguanosine mRNA capping [GO:0006370]; protein dephosphorylation [GO:0006470]; RNA processing [GO:0006396] GO:0004484; GO:0004651; GO:0005524; GO:0005525; GO:0005634; GO:0006370; GO:0006396; GO:0006470; GO:0008138; GO:0008192; GO:0050355; GO:0140818 13180 XM_029343917.2 48 0 6 28 102 NA NA NA NA NA NA 13181 XM_044308754.1 4 0 0 10 68 NA NA NA NA NA NA 13182 XM_029351294.2 1524 1156 949 1374 1011 Q5ZJ75 7.59e-172 Sodium/hydrogen exchanger 8 (Na(+)/H(+) exchanger 8) (NHE-8) (Solute carrier family 9 member 8) Gallus gallus (Chicken) potassium ion transmembrane transport [GO:0071805]; regulation of intracellular pH [GO:0051453] GO:0000139; GO:0015385; GO:0015386; GO:0051453; GO:0071805 13183 XM_044321370.1 3 0 2 5 9 NA NA NA NA NA NA 13184 XM_044315551.1 36 38 35 15 122 NA NA NA NA NA NA 13185 XR_006392186.1 15 0 57 36 0 NA NA NA NA NA NA 13186 XM_029337702.2 603 427 439 362 418 Q5R9B8 7.44e-105 DDB1- and CUL4-associated factor 6 (IQ motif and WD repeat-containing protein 1) (Nuclear receptor interaction protein) (NRIP) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) protein ubiquitination [GO:0016567] GO:0005634; GO:0016567; GO:0080008 13187 XM_029337702.2 603 427 439 362 418 Q5R9B8 3.96e-58 DDB1- and CUL4-associated factor 6 (IQ motif and WD repeat-containing protein 1) (Nuclear receptor interaction protein) (NRIP) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) protein ubiquitination [GO:0016567] GO:0005634; GO:0016567; GO:0080008 13188 XM_029333136.2 838 317 378 566 522 Q96S53 7.2e-84 Dual specificity testis-specific protein kinase 2 (EC 2.7.12.1) (Testicular protein kinase 2) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; focal adhesion assembly [GO:0048041]; protein phosphorylation [GO:0006468]; spermatogenesis [GO:0007283] GO:0004672; GO:0004674; GO:0004712; GO:0004713; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0006468; GO:0007283; GO:0016604; GO:0030036; GO:0046872; GO:0048041; GO:0106310 13189 XM_029350890.2 3000 2134 1523 2757 2354 O60879 1.27e-101 Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) Homo sapiens (Human) actin filament polymerization [GO:0030041]; female gamete generation [GO:0007292]; oogenesis [GO:0048477] GO:0003779; GO:0005102; GO:0005730; GO:0005769; GO:0005783; GO:0005829; GO:0005884; GO:0007292; GO:0030041; GO:0031267; GO:0043231; GO:0048477 13190 XM_029350890.2 3000 2134 1523 2757 2354 O60879 7.98e-97 Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) Homo sapiens (Human) actin filament polymerization [GO:0030041]; female gamete generation [GO:0007292]; oogenesis [GO:0048477] GO:0003779; GO:0005102; GO:0005730; GO:0005769; GO:0005783; GO:0005829; GO:0005884; GO:0007292; GO:0030041; GO:0031267; GO:0043231; GO:0048477 13191 XM_029324016.2 994 3964 778 2638 1522 NA NA NA NA NA NA 13192 XM_044310828.1 11 3 13 11 8 Q91ZV2 7.39e-24 Discoidin, CUB and LCCL domain-containing protein 2 (Endothelial and smooth muscle cell-derived neuropilin-like protein) Rattus norvegicus (Rat) negative regulation of cell growth [GO:0030308]; wound healing [GO:0042060] GO:0005886; GO:0009986; GO:0030308; GO:0038023; GO:0042060 13193 XM_044311787.1 12 0 6 0 20 NA NA NA NA NA NA 13194 XM_044312327.1 1 11 0 24 9 NA NA NA NA NA NA 13195 XR_003823828.2 0 7 0 0 0 NA NA NA NA NA NA 13196 XM_029341488.2 3723 2851 2099 4174 3469 Q8VCD6 6.66e-56 Receptor expression-enhancing protein 2 Mus musculus (Mouse) endoplasmic reticulum tubular network organization [GO:0071786]; protein transport into membrane raft [GO:0032596]; regulation of intracellular transport [GO:0032386]; sensory perception of bitter taste [GO:0050913]; sensory perception of sweet taste [GO:0050916] GO:0005783; GO:0005789; GO:0005881; GO:0005886; GO:0008017; GO:0016020; GO:0031883; GO:0032386; GO:0032596; GO:0050913; GO:0050916; GO:0071782; GO:0071786 13197 XM_029337843.2 2 6 4 3 8 Q32PP9 2.78e-24 Transcription factor Sox-14 Danio rerio (Zebrafish) (Brachydanio rerio) anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; hypothalamus development [GO:0021854]; regulation of DNA-templated transcription [GO:0006355] GO:0000978; GO:0000981; GO:0005634; GO:0006355; GO:0009653; GO:0021854; GO:0030154 13198 XM_044320306.1 245 219 57 239 71 Q9TU53 4.7e-88 Cubilin Canis lupus familiaris (Dog) (Canis familiaris) cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031] GO:0005509; GO:0005765; GO:0005768; GO:0005905; GO:0008203; GO:0015031; GO:0016324; GO:0031419; GO:0031526; GO:0043235 13199 XM_044320306.1 245 219 57 239 71 Q9TU53 6.1e-80 Cubilin Canis lupus familiaris (Dog) (Canis familiaris) cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031] GO:0005509; GO:0005765; GO:0005768; GO:0005905; GO:0008203; GO:0015031; GO:0016324; GO:0031419; GO:0031526; GO:0043235 13200 XM_044320306.1 245 219 57 239 71 Q9TU53 3.91e-74 Cubilin Canis lupus familiaris (Dog) (Canis familiaris) cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031] GO:0005509; GO:0005765; GO:0005768; GO:0005905; GO:0008203; GO:0015031; GO:0016324; GO:0031419; GO:0031526; GO:0043235 13201 XM_044320306.1 245 219 57 239 71 Q9TU53 1.03e-67 Cubilin Canis lupus familiaris (Dog) (Canis familiaris) cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031] GO:0005509; GO:0005765; GO:0005768; GO:0005905; GO:0008203; GO:0015031; GO:0016324; GO:0031419; GO:0031526; GO:0043235 13202 XM_044320306.1 245 219 57 239 71 Q9TU53 7.15e-58 Cubilin Canis lupus familiaris (Dog) (Canis familiaris) cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031] GO:0005509; GO:0005765; GO:0005768; GO:0005905; GO:0008203; GO:0015031; GO:0016324; GO:0031419; GO:0031526; GO:0043235 13203 XM_044320306.1 245 219 57 239 71 Q9TU53 4.9e-40 Cubilin Canis lupus familiaris (Dog) (Canis familiaris) cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031] GO:0005509; GO:0005765; GO:0005768; GO:0005905; GO:0008203; GO:0015031; GO:0016324; GO:0031419; GO:0031526; GO:0043235 13204 XM_029332977.2 61 15 0 0 201 Q9H0B8 6.16e-31 Cysteine-rich secretory protein LCCL domain-containing 2 (Cysteine-rich secretory protein 11) (CRISP-11) (LCCL domain-containing cysteine-rich secretory protein 2) Homo sapiens (Human) extracellular matrix organization [GO:0030198]; face morphogenesis [GO:0060325]; lung development [GO:0030324] GO:0005539; GO:0005576; GO:0005615; GO:0008201; GO:0030133; GO:0030198; GO:0030324; GO:0031012; GO:0034774; GO:0060325; GO:0070062; GO:1904813 13205 XM_044323703.1 0 0 0 0 6 NA NA NA NA NA NA 13206 XM_029338066.2 98 139 92 91 117 NA NA NA NA NA NA 13207 XM_029337253.2 0 146 59 31 2 NA NA NA NA NA NA 13208 XM_044322686.1 11097 9651 6657 11990 9007 Q5XFX0 7.62e-38 Transgelin-2 Rattus norvegicus (Rat) epithelial cell differentiation [GO:0030855] GO:0005856; GO:0030855 13209 XM_044322686.1 11097 9651 6657 11990 9007 Q5XFX0 2.5e-22 Transgelin-2 Rattus norvegicus (Rat) epithelial cell differentiation [GO:0030855] GO:0005856; GO:0030855 13210 XM_029340224.2 112 116 35 63 79 NA NA NA NA NA NA 13211 XM_029340409.2 371 462 233 245 269 Q6IPR3 3.78e-62 tRNA wybutosine-synthesizing protein 3 homolog (tRNA-yW-synthesizing protein 3) (EC 2.1.1.282) (tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase) Homo sapiens (Human) tRNA methylation [GO:0030488] GO:0005737; GO:0008175; GO:0030488 13212 XM_029345493.2 3776 3916 2511 2764 2914 Q5XGU5 1.18e-26 DnaJ homolog subfamily B member 6-B Xenopus laevis (African clawed frog) chaperone-mediated protein folding [GO:0061077] GO:0005634; GO:0030544; GO:0048471; GO:0051082; GO:0061077 13213 XR_003824325.2 57 67 32 51 30 NA NA NA NA NA NA 13214 XM_044313206.1 0 93 121 204 77 NA NA NA NA NA NA 13215 XM_044315025.1 104 0 85 169 508 O57321 1.53e-129 Excitatory amino acid transporter 1 (SEAAT1) (Sodium-dependent glutamate/aspartate transporter) (GLAST) Ambystoma tigrinum (Eastern tiger salamander) chloride transmembrane transport [GO:1902476]; D-aspartate import across plasma membrane [GO:0070779]; L-aspartate import across plasma membrane [GO:0140009]; L-glutamate import across plasma membrane [GO:0098712]; potassium ion transmembrane transport [GO:0071805] GO:0005314; GO:0005886; GO:0015501; GO:0046872; GO:0070779; GO:0071805; GO:0098712; GO:0140009; GO:1902476 13216 XM_044324930.1 0 0 0 7 178 NA NA NA NA NA NA 13217 XM_029356443.2 5320 5402 2766 5196 5608 P11024 0 NAD(P) transhydrogenase, mitochondrial (EC 7.1.1.1) (Nicotinamide nucleotide transhydrogenase) (Pyridine nucleotide transhydrogenase) Bos taurus (Bovine) NADPH regeneration [GO:0006740]; proton transmembrane transport [GO:1902600]; reactive oxygen species metabolic process [GO:0072593] GO:0005743; GO:0006740; GO:0008746; GO:0050661; GO:0051287; GO:0072593; GO:1902600 13218 XM_029339796.2 0 0 45 0 0 Q0VGW6 0 Solute carrier family 12 member 9 (Cation-chloride cotransporter-interacting protein 1) Xenopus laevis (African clawed frog) NA GO:0005886; GO:0015377 13219 XR_006394301.1 42 13 69 34 80 NA NA NA NA NA NA 13220 XM_029343607.2 2 8 18 1 3 NA NA NA NA NA NA 13221 XM_029326892.2 2006 2099 1318 1636 1348 NA NA NA NA NA NA 13222 XM_029346340.2 8 0 86 67 29 Q3MHQ0 1.16e-46 Harmonin (Usher syndrome type-1C protein homolog) Bos taurus (Bovine) brush border assembly [GO:1904970]; cell differentiation [GO:0030154]; protein localization to microvillus [GO:1904106]; regulation of microvillus length [GO:0032532]; sensory perception of sound [GO:0007605] GO:0005829; GO:0005856; GO:0005902; GO:0005903; GO:0007605; GO:0030154; GO:0032532; GO:1904106; GO:1904970 13223 XM_044328699.1 86 77 84 122 133 NA NA NA NA NA NA 13224 XM_029333729.2 3299 1659 1491 2087 1034 Q9D8Z1 9.05e-77 Activating signal cointegrator 1 complex subunit 1 (ASC-1 complex subunit p50) (Trip4 complex subunit p50) Mus musculus (Mouse) DNA repair [GO:0006281]; regulation of DNA-templated transcription [GO:0006355] GO:0003723; GO:0005634; GO:0005667; GO:0006281; GO:0006355; GO:0016607; GO:0031594; GO:1990391 13225 XR_006395116.1 556 679 372 400 354 NA NA NA NA NA NA 13226 XM_044315421.1 0 50 31 0 30 NA NA NA NA NA NA 13227 XM_044321948.1 0 0 94 26 6 NA NA NA NA NA NA 13228 XM_044307019.1 7 4 0 5 11 NA NA NA NA NA NA 13229 XM_029328322.2 0 29 0 136 0 NA NA NA NA NA NA 13230 XM_029337694.2 965 486 493 829 681 NA NA NA NA NA NA 13231 XM_044321005.1 167 125 59 23 39 NA NA NA NA NA NA 13232 XM_029336420.2 312 308 113 369 385 Q8C2A2 2.92e-21 tRNA-splicing endonuclease subunit Sen54 (tRNA-intron endonuclease Sen54) Mus musculus (Mouse) mRNA processing [GO:0006397]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]; tRNA-type intron splice site recognition and cleavage [GO:0000379] GO:0000214; GO:0000379; GO:0005730; GO:0006388; GO:0006397 13233 XM_044327621.1 159 127 60 149 112 NA NA NA NA NA NA 13234 XM_044312993.1 0 21 114 99 157 Q60997 6.35e-34 Deleted in malignant brain tumors 1 protein (Apactin) (CRP-ductin) (Glycoprotein 300) (gp300) (Hensin) (Mucin-like glycoprotein) (Muclin) (Vomeroglandin) (p80) Mus musculus (Mouse) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blastocyst development [GO:0001824]; columnar/cuboidal epithelial cell differentiation [GO:0002065]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterial lipoprotein [GO:0042494]; induction of bacterial agglutination [GO:0043152]; inner cell mass cell proliferation [GO:0001833]; positive regulation of epithelial cell differentiation [GO:0030858]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617] GO:0001530; GO:0001824; GO:0001833; GO:0002065; GO:0003677; GO:0005044; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0009617; GO:0015031; GO:0019898; GO:0030658; GO:0030670; GO:0030858; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0050829; GO:0050830; GO:0050840; GO:0061844; GO:0062023; GO:0070891; GO:1904399 13235 XM_044312993.1 0 21 114 99 157 Q60997 9.57e-30 Deleted in malignant brain tumors 1 protein (Apactin) (CRP-ductin) (Glycoprotein 300) (gp300) (Hensin) (Mucin-like glycoprotein) (Muclin) (Vomeroglandin) (p80) Mus musculus (Mouse) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blastocyst development [GO:0001824]; columnar/cuboidal epithelial cell differentiation [GO:0002065]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterial lipoprotein [GO:0042494]; induction of bacterial agglutination [GO:0043152]; inner cell mass cell proliferation [GO:0001833]; positive regulation of epithelial cell differentiation [GO:0030858]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617] GO:0001530; GO:0001824; GO:0001833; GO:0002065; GO:0003677; GO:0005044; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0009617; GO:0015031; GO:0019898; GO:0030658; GO:0030670; GO:0030858; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0050829; GO:0050830; GO:0050840; GO:0061844; GO:0062023; GO:0070891; GO:1904399 13236 XM_044312993.1 0 21 114 99 157 Q60997 2e-28 Deleted in malignant brain tumors 1 protein (Apactin) (CRP-ductin) (Glycoprotein 300) (gp300) (Hensin) (Mucin-like glycoprotein) (Muclin) (Vomeroglandin) (p80) Mus musculus (Mouse) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blastocyst development [GO:0001824]; columnar/cuboidal epithelial cell differentiation [GO:0002065]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterial lipoprotein [GO:0042494]; induction of bacterial agglutination [GO:0043152]; inner cell mass cell proliferation [GO:0001833]; positive regulation of epithelial cell differentiation [GO:0030858]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617] GO:0001530; GO:0001824; GO:0001833; GO:0002065; GO:0003677; GO:0005044; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0009617; GO:0015031; GO:0019898; GO:0030658; GO:0030670; GO:0030858; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0050829; GO:0050830; GO:0050840; GO:0061844; GO:0062023; GO:0070891; GO:1904399 13237 XM_029341920.2 110 355 28 686 44 P97677 5.36e-84 Delta-like protein 1 (Drosophila Delta homolog 1) (Delta1) Rattus norvegicus (Rat) astrocyte development [GO:0014002]; auditory receptor cell fate commitment [GO:0009912]; cell fate determination [GO:0001709]; cell-cell signaling [GO:0007267]; cerebellar molecular layer formation [GO:0021688]; cerebellar Purkinje cell layer structural organization [GO:0021693]; clathrin-dependent endocytosis [GO:0072583]; compartment pattern specification [GO:0007386]; determination of left/right symmetry [GO:0007368]; endothelial tip cell fate specification [GO:0097102]; energy homeostasis [GO:0097009]; heart looping [GO:0001947]; inhibition of neuroepithelial cell differentiation [GO:0002085]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear development [GO:0048839]; lateral inhibition [GO:0046331]; left/right axis specification [GO:0070986]; loop of Henle development [GO:0072070]; marginal zone B cell differentiation [GO:0002315]; myeloid cell differentiation [GO:0030099]; negative regulation of cardiac muscle cell differentiation [GO:2000726]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal cell differentiation [GO:0045605]; negative regulation of epithelial cell differentiation [GO:0030857]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of inner ear auditory receptor cell differentiation [GO:0045608]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of Notch signaling pathway [GO:0045746]; nephron development [GO:0072006]; nervous system development [GO:0007399]; neuroepithelial cell differentiation [GO:0060563]; neuron differentiation [GO:0030182]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; Notch signaling pathway involved in arterial endothelial cell fate commitment [GO:0060853]; organ growth [GO:0035265]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endocytosis [GO:0045807]; positive regulation of gene expression [GO:0010628]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of skeletal muscle tissue growth [GO:0048633]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proximal tubule development [GO:0072014]; proximal/distal pattern formation [GO:0009954]; regulation of blood pressure [GO:0008217]; regulation of cell adhesion [GO:0030155]; regulation of cell division [GO:0051302]; regulation of growth [GO:0040008]; regulation of neurogenesis [GO:0050767]; regulation of skeletal muscle tissue growth [GO:0048631]; regulation of somitogenesis [GO:0014807]; regulation of vascular endothelial growth factor signaling pathway [GO:1900746]; retina development in camera-type eye [GO:0060041]; retina morphogenesis in camera-type eye [GO:0060042]; skeletal muscle tissue growth [GO:0048630]; skin epidermis development [GO:0098773]; somite specification [GO:0001757]; somitogenesis [GO:0001756]; spinal cord development [GO:0021510]; type B pancreatic cell development [GO:0003323] GO:0001709; GO:0001756; GO:0001757; GO:0001947; GO:0002085; GO:0002315; GO:0003323; GO:0005112; GO:0005509; GO:0005886; GO:0005912; GO:0007219; GO:0007267; GO:0007368; GO:0007386; GO:0007399; GO:0008217; GO:0008284; GO:0008285; GO:0009912; GO:0009954; GO:0010628; GO:0014002; GO:0014807; GO:0016324; GO:0021510; GO:0021688; GO:0021693; GO:0030099; GO:0030155; GO:0030182; GO:0030857; GO:0030957; GO:0031410; GO:0032693; GO:0034351; GO:0035265; GO:0040008; GO:0042491; GO:0045121; GO:0045596; GO:0045605; GO:0045608; GO:0045638; GO:0045662; GO:0045665; GO:0045746; GO:0045747; GO:0045807; GO:0045944; GO:0046331; GO:0048018; GO:0048630; GO:0048631; GO:0048633; GO:0048665; GO:0048839; GO:0050767; GO:0051302; GO:0060041; GO:0060042; GO:0060563; GO:0060853; GO:0070986; GO:0072006; GO:0072014; GO:0072070; GO:0072583; GO:0097009; GO:0097102; GO:0097110; GO:0097150; GO:0098773; GO:1900746; GO:1903672; GO:2000726 13238 XM_029346308.2 59 97 0 0 33 Q6L9W6 1.11e-48 Beta-1,4-N-acetylgalactosaminyltransferase 3 (B4GalNAcT3) (Beta4GalNAc-T3) (Beta4GalNAcT3) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase III) (N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 2) (NGalNAc-T2) Homo sapiens (Human) NA GO:0005794; GO:0008376; GO:0032580; GO:0033842; GO:0043231 13239 XM_044311701.1 53898 48666 29526 37684 28055 Q6PH57 0 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1) Danio rerio (Zebrafish) (Brachydanio rerio) G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of neutrophil migration [GO:1902624]; posterior lateral line neuromast primordium migration [GO:0048920] GO:0005737; GO:0005834; GO:0007186; GO:0030159; GO:0048920; GO:1902624 13240 XR_006395370.1 19 13 0 150 38 NA NA NA NA NA NA 13241 XM_044309970.1 18 18 39 17 21 NA NA NA NA NA NA 13242 XM_029355440.2 1337 622 145 1142 1077 NA NA NA NA NA NA 13243 XM_044320739.1 3 12 43 19 20 Q99315 5.15e-72 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 13244 XM_029339564.2 0 81 44 67 43 Q17RD7 3.39e-71 Synaptotagmin-16 (Chr14Syt) (Synaptotagmin 14-like protein) (Synaptotagmin XIV-related protein) Homo sapiens (Human) NA GO:0005543; GO:0042802 13245 XM_029357542.2 65 51 24 77 85 O75899 2.55e-116 Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51) (HG20) Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway [GO:0007186]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; neuron-glial cell signaling [GO:0150099]; synaptic transmission, GABAergic [GO:0051932] GO:0004888; GO:0004965; GO:0005737; GO:0005886; GO:0007186; GO:0007193; GO:0007194; GO:0007214; GO:0007268; GO:0038039; GO:0043005; GO:0045211; GO:0046982; GO:0051932; GO:0150099; GO:1902710; GO:1902712 13246 XM_029334139.2 4959 5316 4154 6295 6965 Q14444 1.22e-31 Caprin-1 (Cell cycle-associated protein 1) (Cytoplasmic activation- and proliferation-associated protein 1) (GPI-anchored membrane protein 1) (GPI-anchored protein p137) (GPI-p137) (p137GPI) (Membrane component chromosome 11 surface marker 1) (RNA granule protein 105) Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of translation [GO:0017148]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of dendritic spine morphogenesis [GO:0061003] GO:0000932; GO:0003723; GO:0005737; GO:0005829; GO:0010494; GO:0016020; GO:0017148; GO:0030027; GO:0030154; GO:0030425; GO:0031252; GO:0050775; GO:0061003; GO:0098794; GO:0098978 13247 XM_029327038.2 7 5 0 23 0 P81139 3.16e-56 Pancreatic lipase-related protein 2 (PL-RP2) (Cytotoxic T lymphocyte lipase) (GPL) (Galactolipase) (EC 3.1.1.26) (Triacylglycerol lipase) (EC 3.1.1.3) Cavia porcellus (Guinea pig) galactolipid catabolic process [GO:0019376]; lipid metabolic process [GO:0006629]; phospholipid catabolic process [GO:0009395]; phospholipid metabolic process [GO:0006644]; triglyceride catabolic process [GO:0019433] GO:0004620; GO:0004806; GO:0005509; GO:0005615; GO:0006629; GO:0006644; GO:0009395; GO:0016020; GO:0019376; GO:0019433; GO:0031410; GO:0043005; GO:0047372; GO:0047714; GO:0102549 13248 XM_029349603.2 615 1234 414 690 982 NA NA NA NA NA NA 13249 XM_044326511.1 465 451 211 349 312 F1QZ15 5.04e-41 EKC/KEOPS complex subunit TPRKB (PRPK-binding protein) (TP53RK-binding protein) Danio rerio (Zebrafish) (Brachydanio rerio) tRNA threonylcarbamoyladenosine modification [GO:0002949] GO:0000408; GO:0002949; GO:0005634; GO:0005737; GO:0005829 13250 XM_044328811.1 10 4 6 17 0 NA NA NA NA NA NA 13251 XM_044309139.1 680 0 43 0 289 NA NA NA NA NA NA 13252 XM_029353063.2 555 82 98 622 282 NA NA NA NA NA NA 13253 XR_003826878.2 186 35 153 74 550 NA NA NA NA NA NA 13254 XM_044327782.1 8 3 8 18 7 NA NA NA NA NA NA 13255 XM_044326602.1 0 314 7 0 34 NA NA NA NA NA NA 13256 XM_044317757.1 476 191 319 428 552 F1LXF1 2.88e-145 Breakpoint cluster region protein (EC 2.7.11.1) Rattus norvegicus (Rat) actin cytoskeleton organization [GO:0030036]; activation of GTPase activity [GO:0090630]; brain development [GO:0007420]; cell migration [GO:0016477]; cellular response to lipopolysaccharide [GO:0071222]; definitive hemopoiesis [GO:0060216]; establishment of localization in cell [GO:0051649]; focal adhesion assembly [GO:0048041]; homeostasis of number of cells [GO:0048872]; inner ear morphogenesis [GO:0042472]; intracellular protein transmembrane transport [GO:0065002]; keratinocyte differentiation [GO:0030216]; macrophage migration [GO:1905517]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of blood vessel remodeling [GO:0060313]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular extravasation [GO:0002692]; negative regulation of inflammatory response [GO:0050728]; negative regulation of macrophage migration [GO:1905522]; negative regulation of neutrophil degranulation [GO:0043314]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of respiratory burst [GO:0060268]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of phagocytosis [GO:0050766]; protein autophosphorylation [GO:0046777]; regulation of cell cycle [GO:0051726]; regulation of nitrogen compound metabolic process [GO:0051171]; regulation of Rho protein signal transduction [GO:0035023]; regulation of vascular permeability [GO:0043114]; renal system process [GO:0003014]; response to lipopolysaccharide [GO:0032496]; small GTPase mediated signal transduction [GO:0007264] GO:0002692; GO:0003014; GO:0004674; GO:0005085; GO:0005096; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006909; GO:0007264; GO:0007420; GO:0014069; GO:0016020; GO:0016477; GO:0019899; GO:0030036; GO:0030216; GO:0030336; GO:0030424; GO:0032496; GO:0032991; GO:0035023; GO:0042472; GO:0043114; GO:0043197; GO:0043312; GO:0043314; GO:0046777; GO:0048008; GO:0048041; GO:0048872; GO:0050728; GO:0050766; GO:0050804; GO:0050885; GO:0051171; GO:0051649; GO:0051726; GO:0060216; GO:0060268; GO:0060313; GO:0065002; GO:0071222; GO:0090630; GO:0098685; GO:0098978; GO:0099092; GO:0106310; GO:1905517; GO:1905522; GO:2000378 13257 XR_006397899.1 6 0 0 0 0 NA NA NA NA NA NA 13258 XM_044322695.1 328 196 205 1119 382 Q6RI86 1.33e-93 Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Wasabi receptor) Rattus norvegicus (Rat) calcium ion transmembrane import into cytosol [GO:0097553]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cell surface receptor signaling pathway [GO:0007166]; cellular calcium ion homeostasis [GO:0006874]; cellular response to caffeine [GO:0071313]; cellular response to carbon dioxide [GO:0071244]; cellular response to cold [GO:0070417]; cellular response to heat [GO:0034605]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to organic substance [GO:0071310]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; ion transmembrane transport [GO:0034220]; positive regulation of anion transport [GO:1903793]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of sensory perception of pain [GO:1904058]; protein homotetramerization [GO:0051289]; regulation of blood circulation [GO:1903522]; regulation of neuronal action potential [GO:0098908]; response to cold [GO:0009409]; response to hydrogen peroxide [GO:0042542]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; sensory perception of pain [GO:0019233]; thermoception [GO:0050955]; transmembrane transport [GO:0055085]; urinary bladder smooth muscle contraction [GO:0014832] GO:0005216; GO:0005245; GO:0005262; GO:0005886; GO:0006816; GO:0006874; GO:0007166; GO:0009409; GO:0009410; GO:0010033; GO:0014070; GO:0014832; GO:0015267; GO:0015278; GO:0016324; GO:0019233; GO:0030424; GO:0032421; GO:0034220; GO:0034605; GO:0035774; GO:0042542; GO:0042802; GO:0048265; GO:0050955; GO:0050966; GO:0050968; GO:0050974; GO:0051289; GO:0055085; GO:0070301; GO:0070417; GO:0070588; GO:0071244; GO:0071310; GO:0071313; GO:0097553; GO:0097604; GO:0098908; GO:1903522; GO:1903793; GO:1904058; GO:1990760 13259 XM_044322695.1 328 196 205 1119 382 Q6RI86 3.76e-84 Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Wasabi receptor) Rattus norvegicus (Rat) calcium ion transmembrane import into cytosol [GO:0097553]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cell surface receptor signaling pathway [GO:0007166]; cellular calcium ion homeostasis [GO:0006874]; cellular response to caffeine [GO:0071313]; cellular response to carbon dioxide [GO:0071244]; cellular response to cold [GO:0070417]; cellular response to heat [GO:0034605]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to organic substance [GO:0071310]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; ion transmembrane transport [GO:0034220]; positive regulation of anion transport [GO:1903793]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of sensory perception of pain [GO:1904058]; protein homotetramerization [GO:0051289]; regulation of blood circulation [GO:1903522]; regulation of neuronal action potential [GO:0098908]; response to cold [GO:0009409]; response to hydrogen peroxide [GO:0042542]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; sensory perception of pain [GO:0019233]; thermoception [GO:0050955]; transmembrane transport [GO:0055085]; urinary bladder smooth muscle contraction [GO:0014832] GO:0005216; GO:0005245; GO:0005262; GO:0005886; GO:0006816; GO:0006874; GO:0007166; GO:0009409; GO:0009410; GO:0010033; GO:0014070; GO:0014832; GO:0015267; GO:0015278; GO:0016324; GO:0019233; GO:0030424; GO:0032421; GO:0034220; GO:0034605; GO:0035774; GO:0042542; GO:0042802; GO:0048265; GO:0050955; GO:0050966; GO:0050968; GO:0050974; GO:0051289; GO:0055085; GO:0070301; GO:0070417; GO:0070588; GO:0071244; GO:0071310; GO:0071313; GO:0097553; GO:0097604; GO:0098908; GO:1903522; GO:1903793; GO:1904058; GO:1990760 13260 XM_044326190.1 10 3 22 0 36 P10079 7.11e-70 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13261 XM_044326190.1 10 3 22 0 36 P10079 3.15e-68 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13262 XM_044326190.1 10 3 22 0 36 P10079 2.45e-67 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13263 XM_044326190.1 10 3 22 0 36 P10079 5.99e-63 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13264 XM_044326190.1 10 3 22 0 36 P10079 3.71e-55 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13265 XM_044326190.1 10 3 22 0 36 P10079 2.99e-50 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13266 XM_044326190.1 10 3 22 0 36 P10079 1.57e-39 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13267 XM_044308699.1 28 26 0 0 49 NA NA NA NA NA NA 13268 XM_029329757.2 574 904 989 408 22 P42335 4.93e-122 Inositol-trisphosphate 3-kinase B (EC 2.7.1.127) (Inositol 1,4,5-trisphosphate 3-kinase B) (IP3 3-kinase B) (IP3K B) (InsP 3-kinase B) Rattus norvegicus (Rat) cell surface receptor signaling pathway [GO:0007166]; cellular response to calcium ion [GO:0071277]; common myeloid progenitor cell proliferation [GO:0035726]; inositol phosphate biosynthetic process [GO:0032958]; inositol trisphosphate metabolic process [GO:0032957]; MAPK cascade [GO:0000165]; myeloid cell homeostasis [GO:0002262]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of neutrophil apoptotic process [GO:0033030]; phosphatidylinositol phosphate biosynthetic process [GO:0046854]; phosphorylation [GO:0016310]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of Ras protein signal transduction [GO:0046579]; positive thymic T cell selection [GO:0045059]; regulation of protein phosphorylation [GO:0001932]; T cell differentiation [GO:0030217]; thymic T cell selection [GO:0045061] GO:0000165; GO:0000828; GO:0001932; GO:0002262; GO:0005516; GO:0005524; GO:0005634; GO:0005737; GO:0005783; GO:0005829; GO:0005856; GO:0007166; GO:0008440; GO:0016020; GO:0016301; GO:0016310; GO:0030217; GO:0032957; GO:0032958; GO:0033030; GO:0035726; GO:0045059; GO:0045061; GO:0045638; GO:0046579; GO:0046638; GO:0046854; GO:0071277 13269 XM_044313171.1 255 130 70 152 203 Q19269 2.09e-45 Zinc metalloproteinase nas-14 (EC 3.4.24.-) (Nematode astacin 14) Caenorhabditis elegans proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0006508; GO:0008270 13270 XM_044313171.1 255 130 70 152 203 Q19269 6.55e-26 Zinc metalloproteinase nas-14 (EC 3.4.24.-) (Nematode astacin 14) Caenorhabditis elegans proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0006508; GO:0008270 13271 XM_029330044.2 0 0 0 0 68 O67554 2.35e-38 Putative L-lysine 2,3-aminomutase aq_1632 (LAM) (EC 5.4.3.-) Aquifex aeolicus (strain VF5) NA GO:0016853; GO:0046872; GO:0051539 13272 XM_029328356.2 0 0 25 0 0 B0JZG0 0 Solute carrier family 23 member 2 (Na(+)/L-ascorbic acid transporter 2) (Sodium-dependent vitamin C transporter 2) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) sodium ion transport [GO:0006814] GO:0006814; GO:0015229; GO:0015293; GO:0098590 13273 XM_044311912.1 0 2 2 0 42 NA NA NA NA NA NA 13274 XM_029330701.2 146 0 0 0 9 P29119 6.97e-119 Furin-1 (EC 3.4.21.75) (Dibasic-processing enzyme) (Paired basic amino acid residue-cleaving enzyme) (PACE) Xenopus laevis (African clawed frog) positive regulation of transforming growth factor beta1 activation [GO:1901394]; proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0005794; GO:0005886; GO:0006508; GO:0010008; GO:0046872; GO:1901394 13275 XM_044325658.1 0 0 39 0 68 Q3MIE0 6.6e-112 Enoyl-CoA hydratase domain-containing protein 3, mitochondrial Rattus norvegicus (Rat) fatty acid metabolic process [GO:0006631]; positive regulation of cellular response to insulin stimulus [GO:1900078] GO:0004300; GO:0005739; GO:0006631; GO:0016836; GO:1900078 13276 XM_044308259.1 37 14 27 54 54 NA NA NA NA NA NA 13277 XM_044309861.1 50 0 31 23 248 NA NA NA NA NA NA 13278 XR_006391947.1 229 118 146 176 241 Q3UQ28 3.72e-26 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 13279 XR_006391947.1 229 118 146 176 241 Q3UQ28 3.72e-26 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 13280 XR_006391947.1 229 118 146 176 241 Q3UQ28 3.39e-24 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 13281 XR_006391947.1 229 118 146 176 241 Q3UQ28 3.39e-24 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 13282 XM_044323358.1 0 0 0 46 0 Q5RA50 1.85e-26 Protein FAM124A Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA NA 13283 XR_006391883.1 19 30 68 65 108 Q9N2I7 8.46e-24 Dipeptidyl peptidase 4 (EC 3.4.14.5) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (CD antigen CD26) [Cleaved into: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)] Felis catus (Cat) (Felis silvestris catus) cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; T cell costimulation [GO:0031295] GO:0002020; GO:0004177; GO:0004252; GO:0005102; GO:0005576; GO:0005886; GO:0006508; GO:0007155; GO:0008239; GO:0008284; GO:0009986; GO:0010716; GO:0016324; GO:0030027; GO:0030139; GO:0031258; GO:0031295; GO:0042803; GO:0043542; GO:0045121; GO:0070161 13284 XR_006391883.1 19 30 68 65 108 Q9N2I7 8.46e-24 Dipeptidyl peptidase 4 (EC 3.4.14.5) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (CD antigen CD26) [Cleaved into: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)] Felis catus (Cat) (Felis silvestris catus) cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; T cell costimulation [GO:0031295] GO:0002020; GO:0004177; GO:0004252; GO:0005102; GO:0005576; GO:0005886; GO:0006508; GO:0007155; GO:0008239; GO:0008284; GO:0009986; GO:0010716; GO:0016324; GO:0030027; GO:0030139; GO:0031258; GO:0031295; GO:0042803; GO:0043542; GO:0045121; GO:0070161 13285 XR_006396219.1 25 128 63 46 173 NA NA NA NA NA NA 13286 XM_029338562.2 698 843 377 652 637 Q9D6J3 7.19e-81 Splicing factor YJU2 (Coiled-coil domain-containing protein 94) Mus musculus (Mouse) generation of catalytic spliceosome for first transesterification step [GO:0000349]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; RNA splicing [GO:0008380] GO:0000349; GO:0008380; GO:0043518; GO:0046872; GO:0071006 13287 XM_029345422.2 8942 8742 3526 6404 4896 Q99828 3.22e-47 Calcium and integrin-binding protein 1 (CIB) (Calcium- and integrin-binding protein) (CIBP) (Calmyrin) (DNA-PKcs-interacting protein) (Kinase-interacting protein) (KIP) (SNK-interacting protein 2-28) (SIP2-28) Homo sapiens (Human) angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell adhesion [GO:0007155]; cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to growth factor stimulus [GO:0071363]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to tumor necrosis factor [GO:0071356]; cytoplasmic microtubule organization [GO:0031122]; double-strand break repair [GO:0006302]; endomitotic cell cycle [GO:0007113]; extrinsic apoptotic signaling pathway [GO:0097191]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of megakaryocyte differentiation [GO:0045653]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; platelet formation [GO:0030220]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of male germ cell proliferation [GO:2000256]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of cell division [GO:0051302]; regulation of cell population proliferation [GO:0042127]; response to ischemia [GO:0002931]; spermatid development [GO:0007286]; thrombopoietin-mediated signaling pathway [GO:0038163] GO:0000287; GO:0001525; GO:0001933; GO:0001934; GO:0001954; GO:0002931; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005783; GO:0005794; GO:0005813; GO:0005886; GO:0006302; GO:0006915; GO:0006974; GO:0007026; GO:0007113; GO:0007155; GO:0007286; GO:0008284; GO:0008285; GO:0008427; GO:0010977; GO:0016020; GO:0016324; GO:0030027; GO:0030220; GO:0030291; GO:0030307; GO:0030335; GO:0030424; GO:0030426; GO:0031122; GO:0031267; GO:0031982; GO:0032433; GO:0032587; GO:0033630; GO:0038163; GO:0042127; GO:0042383; GO:0043005; GO:0043025; GO:0043066; GO:0043085; GO:0043204; GO:0043495; GO:0044325; GO:0045653; GO:0048471; GO:0051092; GO:0051301; GO:0051302; GO:0051898; GO:0070062; GO:0070374; GO:0070886; GO:0071356; GO:0071363; GO:0071902; GO:0071944; GO:0090050; GO:0090314; GO:0097191; GO:1900026; GO:1903078; GO:1990090; GO:2000256 13288 XR_003828317.2 307 224 141 324 424 NA NA NA NA NA NA 13289 XR_006394715.1 5 91 26 1 0 NA NA NA NA NA NA 13290 XM_029330505.2 8 4 6 16 8 P25931 2.09e-29 RYamide receptor (Neuropeptide Y-like receptor) (NPY-R) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218] GO:0001653; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0016020 13291 XM_029354286.2 0 20 47 35 27 NA NA NA NA NA NA 13292 XM_029350801.2 37 0 0 12 0 O16025 0 Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (AOS) (EC 4.2.1.-) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)] Plexaura homomalla (Black sea rod) arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; lipid oxidation [GO:0034440]; oxylipin biosynthetic process [GO:0031408] GO:0005506; GO:0005737; GO:0006633; GO:0009978; GO:0016020; GO:0019369; GO:0020037; GO:0031408; GO:0034440; GO:0047677 13293 XM_044326710.1 14 10 17 24 27 NA NA NA NA NA NA 13294 XM_044325088.1 0 0 0 0 20 NA NA NA NA NA NA 13295 XM_029337298.2 1626 1101 620 767 947 Q9BWJ5 2.89e-43 Splicing factor 3B subunit 5 (SF3b5) (Pre-mRNA-splicing factor SF3b 10 kDa subunit) Homo sapiens (Human) histone H3 acetylation [GO:0043966]; monoubiquitinated histone deubiquitination [GO:0035521]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA repair [GO:0006282]; regulation of RNA splicing [GO:0043484]; U2-type prespliceosome assembly [GO:1903241] GO:0000124; GO:0000398; GO:0003723; GO:0005634; GO:0005654; GO:0005681; GO:0005684; GO:0005686; GO:0005689; GO:0006282; GO:0035521; GO:0035522; GO:0043484; GO:0043966; GO:0045893; GO:0071005; GO:0071011; GO:1903241; GO:1990935 13296 XM_029342943.2 12937 12329 14163 7943 9174 Q640V2 3.32e-131 E3 ubiquitin-protein ligase RMND5A (EC 2.3.2.27) (Protein RMD5 homolog A) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209] GO:0000151; GO:0000209; GO:0004842; GO:0005634; GO:0005654; GO:0005737; GO:0043161; GO:0046872; GO:0061630 13297 XM_044308379.1 154 0 214 258 2 Q9UJX3 1.5e-112 Anaphase-promoting complex subunit 7 (APC7) (Cyclosome subunit 7) Homo sapiens (Human) anaphase-promoting complex-dependent catabolic process [GO:0031145]; brain development [GO:0007420]; cell division [GO:0051301]; metaphase/anaphase transition of mitotic cell cycle [GO:0007091]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; protein K11-linked ubiquitination [GO:0070979]; protein ubiquitination [GO:0016567]; regulation of meiotic cell cycle [GO:0051445]; regulation of mitotic cell cycle [GO:0007346] GO:0000792; GO:0005634; GO:0005654; GO:0005680; GO:0005737; GO:0005819; GO:0005829; GO:0007091; GO:0007346; GO:0007420; GO:0015630; GO:0016567; GO:0019903; GO:0031145; GO:0045842; GO:0051301; GO:0051445; GO:0070979; GO:0140767 13298 XR_006397676.1 31 39 30 954 51 NA NA NA NA NA NA 13299 XR_006392450.1 34 37 39 49 58 NA NA NA NA NA NA 13300 XM_029355458.2 2092 1065 928 1274 1377 Q6NUP7 0 Serine/threonine-protein phosphatase 4 regulatory subunit 4 Homo sapiens (Human) blastocyst hatching [GO:0001835]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; regulation of protein serine/threonine phosphatase activity [GO:0080163] GO:0001835; GO:0005737; GO:0005829; GO:0008287; GO:0019888; GO:0032515; GO:0080163 13301 XM_044329059.1 138 205 147 286 505 NA NA NA NA NA NA 13302 XM_029351519.2 0 0 0 276 0 Q05BQ1 2.98e-48 Protein turtle homolog A (Dendrite arborization and synapse maturation protein 1) (Immunoglobulin superfamily member 9A) (IgSF9A) Mus musculus (Mouse) cell-cell adhesion [GO:0098609]; dendrite development [GO:0016358]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; regulation of synapse organization [GO:0050807] GO:0005886; GO:0007156; GO:0016358; GO:0030424; GO:0030425; GO:0050807; GO:0060077; GO:0098609; GO:0098632 13303 XM_029344491.2 488 429 442 215 533 A6N6J5 0 WD repeat-containing protein 35 (Naofen) Rattus norvegicus (Rat) cellular response to glucose stimulus [GO:0071333]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to xenobiotic stimulus [GO:0071466]; cilium assembly [GO:0060271]; intraciliary retrograde transport [GO:0035721]; intraciliary transport [GO:0042073]; liver regeneration [GO:0097421]; negative regulation of gene expression [GO:0010629]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vasoconstriction [GO:0045907]; protein localization to cilium [GO:0061512]; response to lipopolysaccharide [GO:0032496]; response to toxic substance [GO:0009636] GO:0005737; GO:0005813; GO:0005930; GO:0009636; GO:0010629; GO:0030991; GO:0032496; GO:0035721; GO:0036064; GO:0042073; GO:0043065; GO:0043280; GO:0045019; GO:0045907; GO:0060271; GO:0061512; GO:0071333; GO:0071356; GO:0071466; GO:0090200; GO:0097421; GO:1990830 13304 XM_044320688.1 7 15 26 19 61 NA NA NA NA NA NA 13305 XR_006396880.1 6 8 0 0 0 NA NA NA NA NA NA 13306 XR_006397705.1 39 29 19 26 43 NA NA NA NA NA NA 13307 XM_029345020.2 4 17 0 6 0 A0JPI9 6.86e-48 Leucine-rich repeat-containing protein 74A (Leucine-rich repeat-containing protein 74) Rattus norvegicus (Rat) NA NA 13308 XM_029337299.2 7370 6590 4885 5719 2546 Q9DCM4 1.36e-52 Dynein axonemal light chain 4 Mus musculus (Mouse) microtubule-based process [GO:0007017] GO:0005737; GO:0005874; GO:0005929; GO:0007017; GO:0030286; GO:0042802 13309 XM_029348400.2 77 15 0 29 0 NA NA NA NA NA NA 13310 XM_044319401.1 37 0 1 8 5 NA NA NA NA NA NA 13311 XM_029352331.2 665 355 375 494 451 Q92609 1.79e-120 TBC1 domain family member 5 Homo sapiens (Human) activation of GTPase activity [GO:0090630]; autophagy [GO:0006914]; macroautophagy [GO:0016236]; positive regulation of receptor internalization [GO:0002092]; protein transport [GO:0015031]; response to starvation [GO:0042594]; retrograde transport, endosome to Golgi [GO:0042147] GO:0002092; GO:0005096; GO:0005776; GO:0005794; GO:0005829; GO:0006914; GO:0010008; GO:0015031; GO:0016236; GO:0030904; GO:0035612; GO:0042147; GO:0042594; GO:0043231; GO:0044877; GO:0090630; GO:1905394 13312 XR_003824847.2 65 28 55 58 209 NA NA NA NA NA NA 13313 XR_006396536.1 352 305 296 374 407 Q14409 0 Glycerol kinase 3 (GK 3) (Glycerokinase 3) (EC 2.7.1.30) (ATP:glycerol 3-phosphotransferase 3) (Glycerol kinase 3 pseudogene) (Glycerol kinase, testis specific 1) Homo sapiens (Human) glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate biosynthetic process [GO:0046167]; phosphorylation [GO:0016310]; triglyceride metabolic process [GO:0006641] GO:0004370; GO:0005524; GO:0005739; GO:0005741; GO:0006071; GO:0006641; GO:0016310; GO:0016773; GO:0019563; GO:0046167 13314 XM_044309301.1 30 29 24 14 88 NA NA NA NA NA NA 13315 XM_044320954.1 68 5 0 12 134 O00370 3.46e-36 LINE-1 retrotransposable element ORF2 protein (ORF2p) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)] Homo sapiens (Human) DNA recombination [GO:0006310]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; reverse transcription involved in RNA-mediated transposition [GO:0032199]; transposition, RNA-mediated [GO:0032197] GO:0003723; GO:0003964; GO:0006310; GO:0009036; GO:0032197; GO:0032199; GO:0046872; GO:0090305 13316 XR_006395802.1 6 2 3 1 3 NA NA NA NA NA NA 13317 XM_029324557.1 422 0 189 228 420 P22933 5.03e-30 Gamma-aminobutyric acid receptor subunit delta (GABA(A) receptor subunit delta) Mus musculus (Mouse) chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165] GO:0004890; GO:0005231; GO:0005254; GO:0005886; GO:0007165; GO:0007268; GO:0030424; GO:0030425; GO:0030594; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0043025; GO:0045202; GO:0045211; GO:0050877; GO:0098978; GO:0098982; GO:1902476; GO:1902711; GO:1904315 13318 XR_006396857.1 793 1236 442 769 199 NA NA NA NA NA NA 13319 XM_029358122.2 1793 1300 1299 1314 1267 P56222 9.25e-88 POU domain, class 3, transcription factor 2 (Brain-specific homeobox/POU domain protein 2) (Brain-2) (Brn-2) (Nervous system-specific octamer-binding transcription factor N-Oct-3) (Octamer-binding protein 7) (Oct-7) (Octamer-binding transcription factor 7) (OTF-7) Rattus norvegicus (Rat) astrocyte development [GO:0014002]; cellular response to organic substance [GO:0071310]; cerebral cortex radially oriented cell migration [GO:0021799]; epidermis development [GO:0008544]; forebrain astrocyte development [GO:0021897]; forebrain ventricular zone progenitor cell division [GO:0021869]; hypothalamus cell differentiation [GO:0021979]; myelination in peripheral nervous system [GO:0022011]; negative regulation of gene expression [GO:0010629]; nervous system development [GO:0007399]; neuroendocrine cell differentiation [GO:0061101]; neurohypophysis development [GO:0021985]; neuron development [GO:0048666]; neuron differentiation [GO:0030182]; neuron fate commitment [GO:0048663]; neuron fate specification [GO:0048665]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of axonogenesis [GO:0050770]; regulation of cell differentiation [GO:0045595]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; Schwann cell development [GO:0014044] GO:0000978; GO:0000981; GO:0001228; GO:0003677; GO:0003700; GO:0005634; GO:0005667; GO:0006355; GO:0006357; GO:0007399; GO:0008284; GO:0008544; GO:0010629; GO:0014002; GO:0014044; GO:0021799; GO:0021869; GO:0021897; GO:0021979; GO:0021985; GO:0022011; GO:0030182; GO:0040018; GO:0042802; GO:0043565; GO:0045595; GO:0045944; GO:0048663; GO:0048665; GO:0048666; GO:0050770; GO:0061101; GO:0071310; GO:0071837; GO:1990837 13320 XM_029324591.2 8 6 4 24 33 NA NA NA NA NA NA 13321 XM_029349302.2 67 186 0 175 18 P04274 4.35e-24 Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor) Mesocricetus auratus (Golden hamster) activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; bone resorption [GO:0045453]; brown fat cell differentiation [GO:0050873]; cellular response to amyloid-beta [GO:1904646]; desensitization of G protein-coupled receptor signaling pathway by arrestin [GO:0002032]; diet induced thermogenesis [GO:0002024]; heat generation [GO:0031649]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of smooth muscle contraction [GO:0045986]; norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0002025]; positive regulation of AMPA receptor activity [GO:2000969]; positive regulation of autophagosome maturation [GO:1901098]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of lipophagy [GO:1904504]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mini excitatory postsynaptic potential [GO:0061885]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor-mediated endocytosis [GO:0006898]; regulation of sodium ion transport [GO:0002028]; response to cold [GO:0009409]; smooth muscle contraction [GO:0006939]; transcription by RNA polymerase II [GO:0006366] GO:0001540; GO:0002024; GO:0002025; GO:0002028; GO:0002032; GO:0004941; GO:0005634; GO:0005769; GO:0005794; GO:0006366; GO:0006898; GO:0006939; GO:0007189; GO:0007190; GO:0008179; GO:0009409; GO:0010739; GO:0015459; GO:0016324; GO:0030501; GO:0031649; GO:0040015; GO:0042803; GO:0043235; GO:0043410; GO:0044877; GO:0045453; GO:0045944; GO:0045986; GO:0050873; GO:0051380; GO:0061885; GO:0071902; GO:0098992; GO:0120162; GO:1901098; GO:1904504; GO:1904646; GO:2000969 13322 XM_044325311.1 80 37 414 41 358 Q04786 7.42e-116 Beta-hexosaminidase (EC 3.2.1.52) (Beta-N-acetylhexosaminidase) (Chitobiase) (N-acetyl-beta-glucosaminidase) Vibrio vulnificus chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272] GO:0000272; GO:0004563; GO:0006032; GO:0030247; GO:0102148 13323 XM_029336323.2 11 0 0 39 7 NA NA NA NA NA NA 13324 XM_029338334.2 18692 14944 8263 17372 15990 Q90705 0 Elongation factor 2 (EF-2) Gallus gallus (Chicken) translational elongation [GO:0006414] GO:0003746; GO:0003924; GO:0005525; GO:0005737; GO:0006414; GO:0043022; GO:1990904 13325 XM_029344490.2 7589 9996 4218 6304 6083 A0A1D8PDZ1 1.19e-37 60S ribosomal protein L34-B Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) ribosome biogenesis [GO:0042254]; translation [GO:0006412] GO:0003735; GO:0006412; GO:0022625; GO:0042254 13326 XM_044314633.1 176 45 103 187 86 NA NA NA NA NA NA 13327 XM_029341163.2 993 1659 464 1687 1936 NA NA NA NA NA NA 13328 XM_029346939.2 737 701 374 925 833 Q6DBY0 0 Nuclear pore complex protein Nup85 (85 kDa nucleoporin) (Nucleoporin Nup85) (Pericentrin-1) Danio rerio (Zebrafish) (Brachydanio rerio) mRNA export from nucleus [GO:0006406]; nephron development [GO:0072006]; positive regulation of DNA-templated transcription [GO:0045893]; protein import into nucleus [GO:0006606] GO:0006406; GO:0006606; GO:0017056; GO:0031080; GO:0031965; GO:0045893; GO:0072006 13329 XM_044308835.1 47 0 14 52 11 Q9H5F2 2.09e-25 Uncharacterized protein CFAP68 (cilia and flagella associated protein 68) Homo sapiens (Human) NA GO:0005654 13330 XM_029351463.2 17 62 188 0 217 NA NA NA NA NA NA 13331 XM_044329194.1 161 12 59 132 0 NA NA NA NA NA NA 13332 XM_044321869.1 4 2 1 1 10 Q6RI86 6.78e-98 Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Wasabi receptor) Rattus norvegicus (Rat) calcium ion transmembrane import into cytosol [GO:0097553]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cell surface receptor signaling pathway [GO:0007166]; cellular calcium ion homeostasis [GO:0006874]; cellular response to caffeine [GO:0071313]; cellular response to carbon dioxide [GO:0071244]; cellular response to cold [GO:0070417]; cellular response to heat [GO:0034605]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to organic substance [GO:0071310]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; ion transmembrane transport [GO:0034220]; positive regulation of anion transport [GO:1903793]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of sensory perception of pain [GO:1904058]; protein homotetramerization [GO:0051289]; regulation of blood circulation [GO:1903522]; regulation of neuronal action potential [GO:0098908]; response to cold [GO:0009409]; response to hydrogen peroxide [GO:0042542]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; sensory perception of pain [GO:0019233]; thermoception [GO:0050955]; transmembrane transport [GO:0055085]; urinary bladder smooth muscle contraction [GO:0014832] GO:0005216; GO:0005245; GO:0005262; GO:0005886; GO:0006816; GO:0006874; GO:0007166; GO:0009409; GO:0009410; GO:0010033; GO:0014070; GO:0014832; GO:0015267; GO:0015278; GO:0016324; GO:0019233; GO:0030424; GO:0032421; GO:0034220; GO:0034605; GO:0035774; GO:0042542; GO:0042802; GO:0048265; GO:0050955; GO:0050966; GO:0050968; GO:0050974; GO:0051289; GO:0055085; GO:0070301; GO:0070417; GO:0070588; GO:0071244; GO:0071310; GO:0071313; GO:0097553; GO:0097604; GO:0098908; GO:1903522; GO:1903793; GO:1904058; GO:1990760 13333 XM_029350333.2 229 206 152 164 292 NA NA NA NA NA NA 13334 XM_044322433.1 0 105 1 1 0 NA NA NA NA NA NA 13335 XM_029350168.2 330 356 295 131 383 NA NA NA NA NA NA 13336 XM_029350872.2 28 0 0 0 29 NA NA NA NA NA NA 13337 XM_029348995.2 7 0 165 314 90 P25931 9.84e-24 RYamide receptor (Neuropeptide Y-like receptor) (NPY-R) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218] GO:0001653; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0016020 13338 XR_006392921.1 41 2 25 5 151 NA NA NA NA NA NA 13339 XM_044313538.1 0 0 0 0 58 Q0R4F1 4.01e-38 ATP-dependent DNA helicase PIF1 (EC 3.6.4.12) (DNA repair and recombination helicase PIF1) Xenopus laevis (African clawed frog) DNA recombination [GO:0006310]; DNA repair [GO:0006281]; mitochondrial genome maintenance [GO:0000002]; telomere maintenance [GO:0000723] GO:0000002; GO:0000723; GO:0003677; GO:0005524; GO:0005634; GO:0005739; GO:0006281; GO:0006310; GO:0016887; GO:0043139 13340 XM_044321776.1 372 0 0 230 65 NA NA NA NA NA NA 13341 XM_029329010.2 401 142 265 235 493 Q92889 0 DNA repair endonuclease XPF (EC 3.1.-.-) (DNA excision repair protein ERCC-4) (DNA repair protein complementing XP-F cells) (Xeroderma pigmentosum group F-complementing protein) Homo sapiens (Human) cellular response to UV [GO:0034644]; DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of double-stranded telomeric DNA binding [GO:1905768]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of telomere maintenance [GO:0032205]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair involved in interstrand cross-link repair [GO:1901255]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; regulation of autophagy [GO:0010506]; resolution of meiotic recombination intermediates [GO:0000712]; response to UV [GO:0009411]; telomere maintenance [GO:0000723]; telomeric DNA-containing double minutes formation [GO:0061819]; UV protection [GO:0009650] GO:0000014; GO:0000109; GO:0000110; GO:0000712; GO:0000723; GO:0000724; GO:0000781; GO:0001094; GO:0003684; GO:0003697; GO:0004520; GO:0005634; GO:0005654; GO:0006281; GO:0006289; GO:0006295; GO:0006296; GO:0006303; GO:0008022; GO:0009411; GO:0009650; GO:0010506; GO:0032205; GO:0034644; GO:0042802; GO:0047485; GO:0061819; GO:0070522; GO:1901255; GO:1904357; GO:1905765; GO:1905768; GO:1990841 13342 XM_029323599.2 206 139 61 240 15 Q86XL3 2.12e-66 Ankyrin repeat and LEM domain-containing protein 2 (LEM domain-containing protein 4) Homo sapiens (Human) cell division [GO:0051301]; central nervous system development [GO:0007417]; mitotic nuclear membrane reassembly [GO:0007084]; negative regulation of apoptotic process [GO:0043066]; negative regulation of phosphorylation [GO:0042326]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of catalytic activity [GO:0050790] GO:0005783; GO:0005789; GO:0007084; GO:0007417; GO:0016020; GO:0019888; GO:0035307; GO:0042326; GO:0043066; GO:0050790; GO:0051301; GO:0051721 13343 XM_044326698.1 101 7 42 27 77 NA NA NA NA NA NA 13344 XM_029327153.2 652 1098 313 461 374 Q5ZKJ0 0 Lipid scramblase CLPTM1L (Cisplatin resistance-related protein 9) (CRR9p) (Cleft lip and palate transmembrane protein 1-like protein) (CLPTM1-like protein) Gallus gallus (Chicken) apoptotic process [GO:0006915] GO:0005789; GO:0006915; GO:0012505; GO:0016020; GO:0017128 13345 XM_029356108.2 232 84 23 34 237 NA NA NA NA NA NA 13346 XM_029331535.2 26 4 42 77 41 NA NA NA NA NA NA 13347 XR_006391967.1 0 31 9 32 2 NA NA NA NA NA NA 13348 XM_029347120.2 195 160 79 299 445 NA NA NA NA NA NA 13349 XM_029356138.2 407 420 364 405 471 Q969W1 5.06e-91 Palmitoyltransferase ZDHHC16 (EC 2.3.1.225) (Abl-philin 2) (Zinc finger DHHC domain-containing protein 16) (DHHC-16) Homo sapiens (Human) apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; eye development [GO:0001654]; heart development [GO:0007507]; protein palmitoylation [GO:0018345]; telencephalon development [GO:0021537] GO:0001654; GO:0005789; GO:0005794; GO:0006915; GO:0006974; GO:0007507; GO:0016409; GO:0018345; GO:0019706; GO:0021537 13350 XM_029332273.2 51 33 0 115 0 A5A779 6.03e-119 Geranylgeranyl transferase type-2 subunit alpha (EC 2.5.1.60) (Geranylgeranyl transferase type II subunit alpha) (Rab geranyl-geranyltransferase subunit alpha) (Rab GG transferase alpha) (Rab GGTase alpha) (Rab geranylgeranyltransferase subunit alpha) Sus scrofa (Pig) protein geranylgeranylation [GO:0018344] GO:0004663; GO:0005737; GO:0005968; GO:0008270; GO:0018344; GO:0031267 13351 XM_044322844.1 58 97 89 136 138 NA NA NA NA NA NA 13352 XM_044322709.1 7 8 6 2 31 NA NA NA NA NA NA 13353 XM_029355167.2 2399 4167 2368 3356 3222 B5X4E0 5.24e-100 Calumenin-B Salmo salar (Atlantic salmon) NA GO:0005509; GO:0005576; GO:0005789; GO:0005794; GO:0033018; GO:0042470 13354 XM_029356243.2 2215 5941 13711 5200 397 NA NA NA NA NA NA 13355 XM_029330311.2 827 790 641 889 1008 Q6P825 2.24e-119 Mitochondrial import receptor subunit TOM40 homolog (Translocase of outer membrane 40 kDa subunit homolog) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) ion transport [GO:0006811]; protein import into mitochondrial matrix [GO:0030150]; protein targeting to mitochondrion [GO:0006626] GO:0005741; GO:0006626; GO:0006811; GO:0008320; GO:0015288; GO:0030150; GO:0046930 13356 XM_029345360.2 3973 4252 2646 2739 2039 NA NA NA NA NA NA 13357 XM_044314503.1 452 309 337 1114 1167 NA NA NA NA NA NA 13358 XM_044306975.1 249 0 153 0 342 A6PWV5 3.11e-67 AT-rich interactive domain-containing protein 3C (ARID domain-containing protein 3C) Mus musculus (Mouse) positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0003677; GO:0003682; GO:0005634; GO:0005737; GO:0006357; GO:0045121; GO:0045944 13359 XM_029348147.2 1093 638 390 773 892 Q6ZMI0 1.69e-158 Protein phosphatase 1 regulatory subunit 21 (Coiled-coil domain-containing protein 128) (KLRAQ motif-containing protein 1) Homo sapiens (Human) NA GO:0005769; GO:0016020 13360 XM_029327323.2 654 478 254 454 411 Q8CI04 0 Conserved oligomeric Golgi complex subunit 3 (COG complex subunit 3) (Component of oligomeric Golgi complex 3) Mus musculus (Mouse) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; glycosylation [GO:0070085]; Golgi organization [GO:0007030]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; protein glycosylation [GO:0006486]; protein localization to organelle [GO:0033365]; protein stabilization [GO:0050821]; retrograde transport, vesicle recycling within Golgi [GO:0000301]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] GO:0000301; GO:0005794; GO:0005801; GO:0005829; GO:0005886; GO:0006486; GO:0006886; GO:0006888; GO:0006890; GO:0006891; GO:0007030; GO:0017119; GO:0032580; GO:0033365; GO:0050821; GO:0070085 13361 XM_029348341.2 776 478 391 904 296 Q1JQA7 4.14e-42 Fructose-2,6-bisphosphatase TIGAR (EC 3.1.3.46) (TP53-induced glycolysis and apoptosis regulator) (TP53-induced glycolysis regulatory phosphatase) Bos taurus (Bovine) cardiac muscle cell apoptotic process [GO:0010659]; cellular response to cobalt ion [GO:0071279]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hypoxia [GO:0071456]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose 2,6-bisphosphate metabolic process [GO:0006003]; glucose catabolic process to lactate via pyruvate [GO:0019661]; glycolytic process [GO:0006096]; intestinal epithelial cell development [GO:0060576]; mitophagy [GO:0000423]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of glycolytic process [GO:0045820]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuron death [GO:1901215]; negative regulation of programmed cell death [GO:0043069]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of DNA repair [GO:0045739]; positive regulation of hexokinase activity [GO:1903301]; reactive oxygen species metabolic process [GO:0072593]; regulation of pentose-phosphate shunt [GO:0043456]; regulation of response to DNA damage checkpoint signaling [GO:1902153]; response to gamma radiation [GO:0010332]; response to ischemia [GO:0002931]; response to xenobiotic stimulus [GO:0009410] GO:0000423; GO:0002931; GO:0004083; GO:0004331; GO:0005634; GO:0005737; GO:0005739; GO:0005741; GO:0005829; GO:0006003; GO:0006096; GO:0006974; GO:0009410; GO:0010332; GO:0010659; GO:0010666; GO:0019661; GO:0030388; GO:0043069; GO:0043456; GO:0045739; GO:0045820; GO:0060576; GO:0071279; GO:0071456; GO:0072593; GO:1901215; GO:1901525; GO:1902153; GO:1903301; GO:1904024; GO:2000378 13362 XM_029333809.2 3713 3162 1665 2252 1317 NA NA NA NA NA NA 13363 XM_029353950.2 277 147 145 328 98 B3EWY8 0 Skeletal aspartic acid-rich protein 2 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 13364 XR_006393537.1 24 10 26 0 92 NA NA NA NA NA NA 13365 XM_029358154.2 784 431 378 572 290 Q810A5 9.29e-42 Microtubule-associated tyrosine carboxypeptidase (EC 3.4.17.17) Mus musculus (Mouse) brain development [GO:0007420]; proteolysis [GO:0006508] GO:0004181; GO:0005737; GO:0005874; GO:0006508; GO:0007420; GO:0046872; GO:0106423 13366 XM_044314766.1 0 0 0 0 12 NA NA NA NA NA NA 13367 XM_029355600.2 52 40 91 93 127 NA NA NA NA NA NA 13368 XM_029342195.2 1461 1141 578 1643 705 NA NA NA NA NA NA 13369 XM_029353005.2 30 26 25 0 13 NA NA NA NA NA NA 13370 XM_044319985.1 358 15 52 127 204 NA NA NA NA NA NA 13371 XR_006394605.1 1 0 0 13 6 NA NA NA NA NA NA 13372 XM_029332797.2 22 49 46 68 94 Q9CZS3 1.71e-26 Centrosomal protein 20 (FGFR1OP N-terminal-like protein) (FOP-related protein of 20 kDa) (LisH domain-containing protein FOPNL) Mus musculus (Mouse) cilium assembly [GO:0060271]; microtubule anchoring [GO:0034453] GO:0005654; GO:0005737; GO:0005813; GO:0005814; GO:0031514; GO:0034451; GO:0034453; GO:0036064; GO:0042802; GO:0060271 13373 XM_029332797.2 22 49 46 68 94 Q9CZS3 1.71e-26 Centrosomal protein 20 (FGFR1OP N-terminal-like protein) (FOP-related protein of 20 kDa) (LisH domain-containing protein FOPNL) Mus musculus (Mouse) cilium assembly [GO:0060271]; microtubule anchoring [GO:0034453] GO:0005654; GO:0005737; GO:0005813; GO:0005814; GO:0031514; GO:0034451; GO:0034453; GO:0036064; GO:0042802; GO:0060271 13374 XM_029333217.2 15654 13184 7835 10369 9673 Q9JHJ0 7.09e-69 Tropomodulin-3 (Ubiquitous tropomodulin) (U-Tmod) Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; erythrocyte development [GO:0048821]; mitotic cell cycle phase transition [GO:0044772]; muscle contraction [GO:0006936]; myofibril assembly [GO:0030239]; pointed-end actin filament capping [GO:0051694]; positive regulation of mitotic cell cycle phase transition [GO:1901992] GO:0001726; GO:0003779; GO:0005523; GO:0005856; GO:0005865; GO:0006936; GO:0007015; GO:0030016; GO:0030027; GO:0030036; GO:0030239; GO:0031941; GO:0044772; GO:0048821; GO:0051011; GO:0051694; GO:1901992 13375 XM_029357628.2 1331 1775 1086 1584 894 NA NA NA NA NA NA 13376 XM_044319978.1 2216 1239 1579 2599 2580 Q6YHK3 0 CD109 antigen (150 kDa TGF-beta-1-binding protein) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7) (Platelet-specific Gov antigen) (p180) (r150) (CD antigen CD109) Homo sapiens (Human) hair follicle development [GO:0001942]; keratinocyte proliferation [GO:0043616]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of peptidase activity [GO:0010466]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of stem cell proliferation [GO:2000647]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of wound healing [GO:0061045]; osteoclast fusion [GO:0072675]; protein phosphorylation [GO:0006468]; regulation of keratinocyte differentiation [GO:0045616]; stem cell proliferation [GO:0072089] GO:0001933; GO:0001942; GO:0004867; GO:0005576; GO:0005615; GO:0005829; GO:0005886; GO:0006468; GO:0009986; GO:0010466; GO:0010839; GO:0030512; GO:0031092; GO:0043616; GO:0045616; GO:0050431; GO:0061045; GO:0072089; GO:0072675; GO:2000647 13377 XR_006394776.1 62 72 32 285 85 NA NA NA NA NA NA 13378 XR_006391867.1 55 218 125 174 54 NA NA NA NA NA NA 13379 XM_044325054.1 33 61 9 0 103 NA NA NA NA NA NA 13380 XM_029336108.2 767 328 454 572 540 O75600 1.47e-172 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial (AKB ligase) (EC 2.3.1.29) (Aminoacetone synthase) (Glycine acetyltransferase) Homo sapiens (Human) amino acid metabolic process [GO:0006520]; biosynthetic process [GO:0009058]; threonine catabolic process [GO:0006567] GO:0005634; GO:0005654; GO:0005739; GO:0005743; GO:0006520; GO:0006567; GO:0008890; GO:0009058; GO:0016607; GO:0030170 13381 XM_029346537.2 0 0 0 0 54 P32297 2.9e-92 Neuronal acetylcholine receptor subunit alpha-3 Homo sapiens (Human) acetylcholine receptor signaling pathway [GO:0095500]; activation of transmembrane receptor protein tyrosine kinase activity [GO:0007171]; behavioral response to nicotine [GO:0035095]; chemical synaptic transmission [GO:0007268]; excitatory postsynaptic potential [GO:0060079]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; locomotory behavior [GO:0007626]; membrane depolarization [GO:0051899]; nervous system development [GO:0007399]; nervous system process [GO:0050877]; regulation of acetylcholine secretion, neurotransmission [GO:0014056]; regulation of dendrite morphogenesis [GO:0048814]; regulation of membrane potential [GO:0042391]; regulation of smooth muscle contraction [GO:0006940]; response to acetylcholine [GO:1905144]; signal transduction [GO:0007165]; synaptic transmission involved in micturition [GO:0060084]; synaptic transmission, cholinergic [GO:0007271] GO:0005231; GO:0005886; GO:0005892; GO:0006811; GO:0006940; GO:0007165; GO:0007171; GO:0007268; GO:0007271; GO:0007399; GO:0007626; GO:0014056; GO:0014069; GO:0015276; GO:0015464; GO:0016020; GO:0016607; GO:0022848; GO:0030425; GO:0030594; GO:0034220; GO:0035095; GO:0042166; GO:0042391; GO:0043005; GO:0043025; GO:0044853; GO:0045202; GO:0045211; GO:0048814; GO:0050877; GO:0051899; GO:0060079; GO:0060084; GO:0095500; GO:1904315; GO:1905144 13382 XM_044321491.1 499 158 127 442 306 Q8VHQ9 1.19e-111 Acyl-coenzyme A thioesterase 11 (Acyl-CoA thioesterase 11) (EC 3.1.2.-) (Acyl-CoA thioester hydrolase 11) (Adipose-associated thioesterase) (Brown fat-inducible thioesterase) (BFIT) (Palmitoyl-coenzyme A thioesterase) (EC 3.1.2.2) Mus musculus (Mouse) acyl-CoA metabolic process [GO:0006637]; fatty acid metabolic process [GO:0006631]; intracellular signal transduction [GO:0035556]; negative regulation of cold-induced thermogenesis [GO:0120163]; response to cold [GO:0009409]; response to temperature stimulus [GO:0009266] GO:0005737; GO:0005759; GO:0005829; GO:0006631; GO:0006637; GO:0009266; GO:0009409; GO:0016290; GO:0035556; GO:0036042; GO:0047617; GO:0052816; GO:0102991; GO:0120163 13383 XM_044328542.1 384 118 234 172 337 Q6EE22 0 RING finger protein unkempt homolog (Zinc finger CCCH domain-containing protein 5) Canis lupus familiaris (Dog) (Canis familiaris) cell morphogenesis involved in neuron differentiation [GO:0048667]; regulation of translation [GO:0006417] GO:0005737; GO:0006417; GO:0046872; GO:0048667; GO:1990715 13384 XM_029333577.2 6 2 2 7 2 NA NA NA NA NA NA 13385 XM_029349866.2 14 36 78 33 29 P50211 1.79e-121 Insulin gene enhancer protein ISL-1 (Islet-1) Gallus gallus (Chicken) atrial septum morphogenesis [GO:0060413]; axonogenesis [GO:0007409]; canonical Wnt signaling pathway [GO:0060070]; cardiac cell fate determination [GO:0060913]; cardiac muscle cell myoblast differentiation [GO:0060379]; cardiac right ventricle morphogenesis [GO:0003215]; cell population proliferation [GO:0008283]; endocardial cushion morphogenesis [GO:0003203]; heart development [GO:0007507]; innervation [GO:0060384]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural crest cell migration [GO:0001755]; neuron fate specification [GO:0048665]; outflow tract septum morphogenesis [GO:0003148]; pancreas development [GO:0031016]; peripheral nervous system neuron axonogenesis [GO:0048936]; pharyngeal system development [GO:0060037]; pituitary gland development [GO:0021983]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA binding [GO:0043388]; positive regulation of granulocyte colony-stimulating factor production [GO:0071657]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of histone acetylation [GO:0035066]; positive regulation of insulin secretion [GO:0032024]; positive regulation of interleukin-1 alpha production [GO:0032730]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type II interferon production [GO:0032729]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of secondary heart field cardioblast proliferation [GO:0003266]; regulation of transcription by RNA polymerase II [GO:0006357]; retinal ganglion cell axon guidance [GO:0031290]; secondary heart field specification [GO:0003139]; sensory system development [GO:0048880]; sinoatrial node cell development [GO:0060931]; spinal cord motor neuron cell fate specification [GO:0021520]; transcription by RNA polymerase II [GO:0006366]; trigeminal nerve development [GO:0021559]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; visceral motor neuron differentiation [GO:0021524] GO:0000122; GO:0000785; GO:0000978; GO:0000981; GO:0000987; GO:0001228; GO:0001755; GO:0003139; GO:0003148; GO:0003203; GO:0003215; GO:0003266; GO:0005634; GO:0006357; GO:0006366; GO:0007409; GO:0007507; GO:0008283; GO:0008284; GO:0010575; GO:0021520; GO:0021524; GO:0021559; GO:0021983; GO:0031016; GO:0031290; GO:0032024; GO:0032725; GO:0032729; GO:0032730; GO:0032731; GO:0032735; GO:0032755; GO:0032760; GO:0035066; GO:0042531; GO:0043388; GO:0043425; GO:0043524; GO:0045597; GO:0045665; GO:0045766; GO:0045892; GO:0045944; GO:0046872; GO:0048665; GO:0048880; GO:0048936; GO:0050728; GO:0055010; GO:0060037; GO:0060070; GO:0060379; GO:0060384; GO:0060413; GO:0060913; GO:0060931; GO:0061629; GO:0071657; GO:0086091; GO:0090090; GO:1990841 13386 XM_029332035.2 137 36 14 106 82 P32442 6.08e-29 Homeobox protein MOX-1 (Mesenchyme homeobox 1) Mus musculus (Mouse) hematopoietic stem cell differentiation [GO:0060218]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; sclerotome development [GO:0061056]; somite development [GO:0061053]; somite specification [GO:0001757] GO:0000978; GO:0000981; GO:0001228; GO:0001757; GO:0003682; GO:0003700; GO:0005634; GO:0005737; GO:0006357; GO:0043565; GO:0045944; GO:0060218; GO:0061053; GO:0061056; GO:0071837; GO:1990837 13387 XM_044308739.1 12 0 15 17 12 NA NA NA NA NA NA 13388 XM_029341099.2 6 28 0 54 37 Q969Q5 9.79e-69 Ras-related protein Rab-24 Homo sapiens (Human) autophagy [GO:0006914]; intracellular protein transport [GO:0006886] GO:0003924; GO:0005525; GO:0005768; GO:0005776; GO:0005829; GO:0005886; GO:0006886; GO:0006914; GO:0012505; GO:0030139; GO:0030667 13389 XR_006394673.1 12 5 15 7 36 NA NA NA NA NA NA 13390 XM_029327525.2 6331 8687 3203 1380 1482 NA NA NA NA NA NA 13391 XM_029350670.2 564 326 1636 96 1902 P54288 1.31e-124 Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2) Oryctolagus cuniculus (Rabbit) calcium ion import [GO:0070509]; chemical synaptic transmission [GO:0007268]; membrane depolarization during atrial cardiac muscle cell action potential [GO:0098912]; positive regulation of calcium ion transport [GO:0051928]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ion transmembrane transport [GO:0034765]; visual perception [GO:0007601] GO:0007268; GO:0007601; GO:0008331; GO:0034765; GO:0051015; GO:0051928; GO:0070509; GO:0086056; GO:0086091; GO:0098684; GO:0098793; GO:0098912; GO:0099626; GO:1990454 13392 XR_006392862.1 107 5 8 4 14 NA NA NA NA NA NA 13393 XM_029349169.2 0 0 118 54 73 Q9CPV7 2.05e-97 Palmitoyltransferase ZDHHC6 (EC 2.3.1.225) (Stearoyltransferase ZDHHC6) (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 6) (DHHC-6) Mus musculus (Mouse) peptidyl-L-cysteine S-palmitoylation [GO:0018230]; positive regulation of mitochondrial fusion [GO:0010636]; protein palmitoylation [GO:0018345]; protein stearoylation [GO:0140438]; protein targeting to membrane [GO:0006612] GO:0005783; GO:0005789; GO:0005794; GO:0006612; GO:0010636; GO:0016409; GO:0018230; GO:0018345; GO:0019706; GO:0140438; GO:0140439 13394 XM_029335164.2 165 158 151 254 255 A2A870 2.94e-65 Fas-binding factor 1 (FBF-1) Mus musculus (Mouse) apical junction assembly [GO:0043297]; cilium assembly [GO:0060271]; establishment of epithelial cell polarity [GO:0090162] GO:0000922; GO:0005737; GO:0005813; GO:0005814; GO:0036064; GO:0043296; GO:0043297; GO:0045095; GO:0060271; GO:0090162; GO:0097539 13395 XM_044316849.1 105 135 19 61 40 NA NA NA NA NA NA 13396 XM_044326500.1 20 17 20 24 113 NA NA NA NA NA NA 13397 XM_044323466.1 17 1 1 15 6 Q96AY4 1.82e-123 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13398 XM_044323466.1 17 1 1 15 6 Q96AY4 7.28e-81 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13399 XM_044323466.1 17 1 1 15 6 Q96AY4 1.32e-76 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13400 XM_044323466.1 17 1 1 15 6 Q96AY4 1.11e-66 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13401 XM_029335826.2 30 4 0 2 3 Q708S4 8.96e-36 Acid-sensing ion channel 4-A (ASIC4-A) (Acid-sensing ion channel 4.1) (Amiloride-sensitive cation channel 4-A) (ZASIC4.1) Danio rerio (Zebrafish) (Brachydanio rerio) sodium ion transmembrane transport [GO:0035725] GO:0005248; GO:0005261; GO:0005886; GO:0015280; GO:0035725; GO:0045177 13402 XM_029356214.2 961 549 507 512 666 NA NA NA NA NA NA 13403 XM_044320962.1 198 163 75 279 185 NA NA NA NA NA NA 13404 XR_006393261.1 208 3 161 178 353 NA NA NA NA NA NA 13405 XM_044328531.1 46 7 0 0 0 Q8H1F7 3.07e-24 Isopentenyl phosphate kinase (AtIPK) (IPK) (EC 2.7.4.26) Arabidopsis thaliana (Mouse-ear cress) phosphorylation [GO:0016310]; terpenoid biosynthetic process [GO:0016114] GO:0005524; GO:0005829; GO:0016114; GO:0016301; GO:0016310; GO:0102043 13406 XR_003825554.2 450 81 488 64 56 NA NA NA NA NA NA 13407 XM_029349454.2 40 34 58 21 129 P54833 1.74e-21 Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor) Canis lupus familiaris (Dog) (Canis familiaris) activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; desensitization of G protein-coupled receptor signaling pathway by arrestin [GO:0002032]; negative regulation of smooth muscle contraction [GO:0045986]; norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0002025]; positive regulation of autophagosome maturation [GO:1901098]; positive regulation of lipophagy [GO:1904504]; positive regulation of MAPK cascade [GO:0043410]; receptor-mediated endocytosis [GO:0006898] GO:0002025; GO:0002032; GO:0004930; GO:0004941; GO:0005769; GO:0005794; GO:0005886; GO:0006898; GO:0007190; GO:0042803; GO:0043235; GO:0043410; GO:0045986; GO:0051380; GO:0071880; GO:1901098; GO:1904504 13408 XM_029347804.2 1497 3815 635 1941 1437 P56965 9.35e-69 N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (DDAH-1) (Dimethylarginine dimethylaminohydrolase 1) (EC 3.5.3.18) (DDAHI) (Dimethylargininase-1) Bos taurus (Bovine) arginine catabolic process [GO:0006527]; arginine metabolic process [GO:0006525]; citrulline metabolic process [GO:0000052]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cellular response to hypoxia [GO:1900038]; negative regulation of vascular permeability [GO:0043116]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; protein nitrosylation [GO:0017014]; regulation of systemic arterial blood pressure [GO:0003073] GO:0000052; GO:0003073; GO:0006525; GO:0006527; GO:0006809; GO:0008270; GO:0008285; GO:0016403; GO:0016597; GO:0017014; GO:0043116; GO:0045429; GO:1900038 13409 XM_044317741.1 73 37 0 696 922 P81628 1.97e-34 Endoplasmic reticulum resident protein 29 (ERp29) Gallus gallus (Chicken) protein secretion [GO:0009306] GO:0005783; GO:0005788; GO:0009306 13410 XM_044317290.1 8 13 5 0 64 NA NA NA NA NA NA 13411 XM_029342791.2 5 0 15 10 46 NA NA NA NA NA NA 13412 XM_029338335.2 90 99 53 149 71 E7FAM5 8.73e-138 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 13413 XM_029327126.2 85 784 52 791 585 P18130 9.27e-30 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) Bos taurus (Bovine) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of vasoconstriction [GO:0045907]; regulation of cardiac muscle contraction [GO:0055117] GO:0001996; GO:0004930; GO:0004937; GO:0005634; GO:0005737; GO:0005886; GO:0005901; GO:0007200; GO:0007204; GO:0007267; GO:0031965; GO:0043410; GO:0045907; GO:0046982; GO:0055117; GO:0071880 13414 XM_044322105.1 104 571 920 1822 4235 Q9UA35 4.82e-149 Solute carrier family 28 member 3 (Concentrative Na(+)-nucleoside cotransporter 3) (hfCNT) Eptatretus stoutii (Pacific hagfish) NA GO:0005337; GO:0005886; GO:0015293 13415 XM_044307750.1 311 201 151 156 263 Q92733 6.52e-25 Proline-rich protein PRCC (Papillary renal cell carcinoma translocation-associated gene protein) Homo sapiens (Human) cell cycle [GO:0007049]; regulation of cell cycle [GO:0051726] GO:0005634; GO:0005654; GO:0007049; GO:0016607; GO:0051726 13416 XM_044320067.1 270 38 48 97 106 Q0EEE2 1.24e-70 Patched domain-containing protein 3 (RND-type protein RNDEu-3) Mus musculus (Mouse) NA GO:0005783; GO:0005789; GO:0005886; GO:0016020; GO:0097225 13417 XM_029339182.2 167 212 207 190 131 NA NA NA NA NA NA 13418 XM_029337561.2 1 9 0 0 0 NA NA NA NA NA NA 13419 XM_044318713.1 51 48 51 93 179 Q6UXZ4 1.2e-36 Netrin receptor UNC5D (Protein unc-5 homolog 4) (Protein unc-5 homolog D) Homo sapiens (Human) apoptotic process [GO:0006915]; axon guidance [GO:0007411]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; pyramidal neuron differentiation [GO:0021859]; regulation of neuron migration [GO:2001222] GO:0005042; GO:0005886; GO:0006915; GO:0007411; GO:0009986; GO:0021859; GO:0098742; GO:2001222 13420 XM_044318713.1 51 48 51 93 179 Q6UXZ4 5.62e-21 Netrin receptor UNC5D (Protein unc-5 homolog 4) (Protein unc-5 homolog D) Homo sapiens (Human) apoptotic process [GO:0006915]; axon guidance [GO:0007411]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; pyramidal neuron differentiation [GO:0021859]; regulation of neuron migration [GO:2001222] GO:0005042; GO:0005886; GO:0006915; GO:0007411; GO:0009986; GO:0021859; GO:0098742; GO:2001222 13421 XM_044316551.1 0 160 196 48 95 NA NA NA NA NA NA 13422 XM_044312615.1 42 5 49 24 115 NA NA NA NA NA NA 13423 XM_044316186.1 639 178 101 91 303 NA NA NA NA NA NA 13424 XM_044325067.1 0 63 0 0 1 NA NA NA NA NA NA 13425 XM_044323056.1 139 135 159 246 184 Q08DY9 2.1e-38 Caspase-3 (CASP-3) (EC 3.4.22.56) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12] Bos taurus (Bovine) positive regulation of amyloid-beta formation [GO:1902004]; proteolysis [GO:0006508]; regulation of protein stability [GO:0031647] GO:0004175; GO:0005737; GO:0006508; GO:0031647; GO:0097153; GO:0097199; GO:0097200; GO:1902004 13426 XM_044312157.1 0 7 3 1 22 NA NA NA NA NA NA 13427 XM_044314538.1 182 243 31 444 214 NA NA NA NA NA NA 13428 XM_029341529.2 135 225 244 0 1435 NA NA NA NA NA NA 13429 XM_029342335.2 399 352 213 357 310 NA NA NA NA NA NA 13430 XM_044316498.1 841 2034 2084 1779 2386 Q9H4G4 1.27e-28 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Homo sapiens (Human) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070062; GO:0070374 13431 XM_044316498.1 841 2034 2084 1779 2386 Q9H4G4 2.68e-28 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Homo sapiens (Human) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070062; GO:0070374 13432 XM_044308689.1 410 115 31 307 80 Q96DM1 1.27e-61 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 13433 XM_029335210.2 66 36 82 45 107 Q63244 5.53e-36 Forkhead box protein Q1 (HNF-3/forkhead-like protein 1) (HFH-1) (Hepatocyte nuclear factor 3 forkhead homolog 1) Rattus norvegicus (Rat) anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; hair follicle morphogenesis [GO:0031069]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000978; GO:0000981; GO:0001227; GO:0005634; GO:0006357; GO:0009653; GO:0030154; GO:0031069; GO:0043524; GO:1990837 13434 XR_006391834.1 14 4 17 1 8 NA NA NA NA NA NA 13435 XM_029340139.2 0 34 0 0 28 Q96E11 9.9e-37 Ribosome-recycling factor, mitochondrial (RRF) (Ribosome-releasing factor, mitochondrial) Homo sapiens (Human) ribosome disassembly [GO:0032790]; translation [GO:0006412] GO:0005739; GO:0005759; GO:0006412; GO:0032790; GO:0043023 13436 XM_029324025.2 3 2 2 1 18 NA NA NA NA NA NA 13437 XM_029352675.2 0 21 6 12 0 P49183 1.45e-66 Deoxyribonuclease-1 (EC 3.1.21.1) (Deoxyribonuclease I) (DNase I) Mus musculus (Mouse) apoptotic process [GO:0006915]; DNA catabolic process [GO:0006308]; DNA catabolic process, endonucleolytic [GO:0000737]; neutrophil activation involved in immune response [GO:0002283]; regulation of acute inflammatory response [GO:0002673]; regulation of neutrophil mediated cytotoxicity [GO:0070948] GO:0000737; GO:0002283; GO:0002673; GO:0003677; GO:0003779; GO:0004530; GO:0004536; GO:0005576; GO:0005634; GO:0005635; GO:0006308; GO:0006915; GO:0042588; GO:0070948 13438 XM_044318099.1 6 10 1 0 37 NA NA NA NA NA NA 13439 XR_006395486.1 2 6 10 0 2 NA NA NA NA NA NA 13440 XM_029335060.2 297 268 182 696 244 P97698 5.08e-157 Smoothened homolog (SMO) Rattus norvegicus (Rat) alpha-tubulin acetylation [GO:0071929]; anterior/posterior pattern specification [GO:0009952]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; atrial septum morphogenesis [GO:0060413]; axon extension involved in axon guidance [GO:0048846]; cell development [GO:0048468]; cell fate specification [GO:0001708]; cell population proliferation [GO:0008283]; cellular response to cholesterol [GO:0071397]; central nervous system development [GO:0007417]; central nervous system neuron differentiation [GO:0021953]; cerebellar cortex morphogenesis [GO:0021696]; cerebral cortex development [GO:0021987]; commissural neuron axon guidance [GO:0071679]; contact inhibition [GO:0060242]; dentate gyrus development [GO:0021542]; determination of left/right asymmetry in lateral mesoderm [GO:0003140]; determination of left/right symmetry [GO:0007368]; developmental growth [GO:0048589]; digestive tract development [GO:0048565]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral neural tube patterning [GO:0021904]; dorsal/ventral pattern formation [GO:0009953]; embryonic organ development [GO:0048568]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation [GO:0050673]; epithelial-mesenchymal cell signaling [GO:0060684]; facial nerve development [GO:0021561]; forebrain morphogenesis [GO:0048853]; hair follicle development [GO:0001942]; hair follicle morphogenesis [GO:0031069]; heart looping [GO:0001947]; heart morphogenesis [GO:0003007]; homeostasis of number of cells within a tissue [GO:0048873]; in utero embryonic development [GO:0001701]; left/right axis specification [GO:0070986]; mammary gland epithelial cell differentiation [GO:0060644]; mesenchymal to epithelial transition [GO:0060231]; mesenchymal to epithelial transition involved in metanephric renal vesicle formation [GO:0072285]; midgut development [GO:0007494]; multicellular organism growth [GO:0035264]; myoblast migration [GO:0051451]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of epithelial cell differentiation [GO:0030857]; negative regulation of gene expression [GO:0010629]; negative regulation of hair follicle development [GO:0051799]; negative regulation of hepatocyte proliferation [GO:2000346]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural crest cell migration [GO:0001755]; neuroblast proliferation [GO:0007405]; neuron projection regeneration [GO:0031102]; odontogenesis of dentin-containing tooth [GO:0042475]; ossification [GO:0001503]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; pancreas morphogenesis [GO:0061113]; pattern specification process [GO:0007389]; positive regulation of autophagy [GO:0010508]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of gene expression [GO:0010628]; positive regulation of hepatic stellate cell activation [GO:2000491]; positive regulation of hh target transcription factor activity [GO:0007228]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of organ growth [GO:0046622]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; protein import into nucleus [GO:0006606]; protein localization to nucleus [GO:0034504]; protein stabilization [GO:0050821]; regulation of gene expression [GO:0010468]; regulation of heart morphogenesis [GO:2000826]; regulation of somatic stem cell population maintenance [GO:1904672]; regulation of stem cell population maintenance [GO:2000036]; response to organic substance [GO:0010033]; response to wounding [GO:0009611]; skeletal muscle fiber development [GO:0048741]; smooth muscle tissue development [GO:0048745]; smoothened signaling pathway [GO:0007224]; smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation [GO:0021938]; smoothened signaling pathway involved in ventral spinal cord patterning [GO:0021910]; somite development [GO:0061053]; spermatogenesis [GO:0007283]; thalamus development [GO:0021794]; type B pancreatic cell development [GO:0003323]; vasculogenesis [GO:0001570]; ventral midline determination [GO:0007371] GO:0000122; GO:0001503; GO:0001570; GO:0001649; GO:0001701; GO:0001708; GO:0001755; GO:0001942; GO:0001947; GO:0002052; GO:0002053; GO:0003007; GO:0003140; GO:0003323; GO:0004930; GO:0005113; GO:0005634; GO:0005737; GO:0005814; GO:0005886; GO:0005929; GO:0006606; GO:0006915; GO:0007224; GO:0007228; GO:0007283; GO:0007368; GO:0007371; GO:0007389; GO:0007405; GO:0007417; GO:0007494; GO:0008283; GO:0008284; GO:0009611; GO:0009952; GO:0009953; GO:0010033; GO:0010468; GO:0010508; GO:0010628; GO:0010629; GO:0014069; GO:0016020; GO:0021542; GO:0021561; GO:0021696; GO:0021794; GO:0021904; GO:0021910; GO:0021938; GO:0021953; GO:0021987; GO:0030335; GO:0030425; GO:0030855; GO:0030857; GO:0031069; GO:0031102; GO:0033687; GO:0034504; GO:0035264; GO:0040018; GO:0042307; GO:0042475; GO:0043025; GO:0043066; GO:0043231; GO:0043392; GO:0043524; GO:0044294; GO:0044295; GO:0045880; GO:0045892; GO:0045893; GO:0045944; GO:0046622; GO:0048143; GO:0048468; GO:0048565; GO:0048568; GO:0048589; GO:0048741; GO:0048745; GO:0048846; GO:0048853; GO:0048873; GO:0050673; GO:0050679; GO:0050821; GO:0051451; GO:0051799; GO:0060170; GO:0060231; GO:0060242; GO:0060413; GO:0060644; GO:0060684; GO:0061053; GO:0061113; GO:0070986; GO:0071397; GO:0071542; GO:0071679; GO:0071929; GO:0072285; GO:0090190; GO:0097731; GO:1901215; GO:1904672; GO:1904754; GO:2000036; GO:2000179; GO:2000346; GO:2000491; GO:2000826 13441 XR_006392007.1 468 47 329 33 14 NA NA NA NA NA NA 13442 XM_029345818.2 716 399 637 378 958 Q5IS99 2.98e-44 Caspase-3 (CASP-3) (EC 3.4.22.56) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12] Saimiri boliviensis boliviensis (Bolivian squirrel monkey) cellular response to staurosporine [GO:0072734]; erythrocyte differentiation [GO:0030218]; intracellular signal transduction [GO:0035556]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of amyloid-beta formation [GO:1902004]; proteolysis [GO:0006508]; regulation of protein stability [GO:0031647] GO:0004175; GO:0005634; GO:0005829; GO:0006508; GO:0030218; GO:0031647; GO:0035556; GO:0048011; GO:0072734; GO:0097153; GO:0097199; GO:0097200; GO:1902004 13443 XM_044315743.1 0 99 0 0 0 O43854 4.68e-50 EGF-like repeat and discoidin I-like domain-containing protein 3 (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1) Homo sapiens (Human) cell adhesion [GO:0007155]; positive regulation of cell-substrate adhesion [GO:0010811] GO:0005178; GO:0005509; GO:0007155; GO:0010811; GO:0062023; GO:0070062; GO:1903561 13444 XM_044315743.1 0 99 0 0 0 O43854 1.06e-49 EGF-like repeat and discoidin I-like domain-containing protein 3 (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1) Homo sapiens (Human) cell adhesion [GO:0007155]; positive regulation of cell-substrate adhesion [GO:0010811] GO:0005178; GO:0005509; GO:0007155; GO:0010811; GO:0062023; GO:0070062; GO:1903561 13445 XM_044315743.1 0 99 0 0 0 O43854 1.06e-49 EGF-like repeat and discoidin I-like domain-containing protein 3 (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1) Homo sapiens (Human) cell adhesion [GO:0007155]; positive regulation of cell-substrate adhesion [GO:0010811] GO:0005178; GO:0005509; GO:0007155; GO:0010811; GO:0062023; GO:0070062; GO:1903561 13446 XM_044315743.1 0 99 0 0 0 O43854 1.06e-49 EGF-like repeat and discoidin I-like domain-containing protein 3 (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1) Homo sapiens (Human) cell adhesion [GO:0007155]; positive regulation of cell-substrate adhesion [GO:0010811] GO:0005178; GO:0005509; GO:0007155; GO:0010811; GO:0062023; GO:0070062; GO:1903561 13447 XM_044315743.1 0 99 0 0 0 O43854 2.73e-49 EGF-like repeat and discoidin I-like domain-containing protein 3 (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1) Homo sapiens (Human) cell adhesion [GO:0007155]; positive regulation of cell-substrate adhesion [GO:0010811] GO:0005178; GO:0005509; GO:0007155; GO:0010811; GO:0062023; GO:0070062; GO:1903561 13448 XM_044315743.1 0 99 0 0 0 O43854 3.08e-49 EGF-like repeat and discoidin I-like domain-containing protein 3 (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1) Homo sapiens (Human) cell adhesion [GO:0007155]; positive regulation of cell-substrate adhesion [GO:0010811] GO:0005178; GO:0005509; GO:0007155; GO:0010811; GO:0062023; GO:0070062; GO:1903561 13449 XM_044315743.1 0 99 0 0 0 O43854 1.27e-48 EGF-like repeat and discoidin I-like domain-containing protein 3 (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1) Homo sapiens (Human) cell adhesion [GO:0007155]; positive regulation of cell-substrate adhesion [GO:0010811] GO:0005178; GO:0005509; GO:0007155; GO:0010811; GO:0062023; GO:0070062; GO:1903561 13450 XM_044315743.1 0 99 0 0 0 O43854 2.92e-21 EGF-like repeat and discoidin I-like domain-containing protein 3 (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1) Homo sapiens (Human) cell adhesion [GO:0007155]; positive regulation of cell-substrate adhesion [GO:0010811] GO:0005178; GO:0005509; GO:0007155; GO:0010811; GO:0062023; GO:0070062; GO:1903561 13451 XM_029334501.2 187 0 372 559 474 NA NA NA NA NA NA 13452 XM_044325868.1 205 107 187 259 299 NA NA NA NA NA NA 13453 XM_044311944.1 411 180 171 412 192 Q76KP1 2.62e-71 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Homo sapiens (Human) NA GO:0008376; GO:0032580; GO:0033842 13454 XM_044311944.1 411 180 171 412 192 Q76KP1 1.04e-31 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Homo sapiens (Human) NA GO:0008376; GO:0032580; GO:0033842 13455 XM_044308426.1 122 158 97 122 117 NA NA NA NA NA NA 13456 XR_003827626.1 2 7 2 9 4 NA NA NA NA NA NA 13457 XM_029336460.2 831 688 494 796 776 B2RXZ1 3.12e-84 Poly(A)-specific ribonuclease PNLDC1 (EC 3.1.13.4) (PARN-like domain-containing protein 1) (Poly(A)-specific ribonuclease domain-containing protein 1) Mus musculus (Mouse) blastocyst formation [GO:0001825]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; piRNA processing [GO:0034587]; spermatogenesis [GO:0007283] GO:0000175; GO:0000184; GO:0000289; GO:0001825; GO:0003723; GO:0004535; GO:0005737; GO:0005783; GO:0005789; GO:0007283; GO:0034587; GO:0046872 13458 XM_044313651.1 38 120 19 112 79 Q924C1 2.42e-57 Exportin-5 (Exp5) (Ran-binding protein 21) Mus musculus (Mouse) positive regulation of post-transcriptional gene silencing by RNA [GO:1900370]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; RNA export from nucleus [GO:0006405] GO:0000049; GO:0003723; GO:0003729; GO:0005049; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006405; GO:0006611; GO:0016442; GO:0031267; GO:0035281; GO:0042565; GO:0070883; GO:1900370; GO:1905172 13459 XM_029330391.2 339 111 73 325 529 Q5U239 1.05e-125 Transmembrane protein 145 Xenopus laevis (African clawed frog) G protein-coupled receptor signaling pathway [GO:0007186]; response to pheromone [GO:0019236] GO:0007186; GO:0016020; GO:0019236 13460 XR_006397711.1 63 98 46 65 9 NA NA NA NA NA NA 13461 XM_029334996.2 36 17 6 251 91 NA NA NA NA NA NA 13462 XM_044313767.1 3 0 0 1 16 NA NA NA NA NA NA 13463 XM_029326929.2 185 205 0 119 289 Q90268 2.79e-58 Paired box protein Pax-2a (No isthmus protein) (Pax[Zf-b]) Danio rerio (Zebrafish) (Brachydanio rerio) anatomical structure development [GO:0048856]; anterior/posterior pattern specification [GO:0009952]; anterior/posterior pattern specification involved in pronephros development [GO:0034672]; cell fate specification [GO:0001708]; cerebellum development [GO:0021549]; cerebellum formation [GO:0021588]; cilium assembly [GO:0060271]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic pattern specification [GO:0009880]; hindbrain development [GO:0030902]; inner ear receptor cell differentiation [GO:0060113]; kidney development [GO:0001822]; locus ceruleus development [GO:0021703]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; nervous system development [GO:0007399]; otic placode formation [GO:0043049]; peripheral nervous system development [GO:0007422]; pronephric glomerulus morphogenesis [GO:0035775]; pronephros development [GO:0048793]; pronephros morphogenesis [GO:0072114]; regulation of transcription by RNA polymerase II [GO:0006357]; thyroid gland development [GO:0030878]; vestibular receptor cell development [GO:0060118] GO:0000978; GO:0000981; GO:0001708; GO:0001822; GO:0003677; GO:0003700; GO:0005634; GO:0006357; GO:0007399; GO:0007422; GO:0009880; GO:0009952; GO:0021549; GO:0021588; GO:0021703; GO:0030878; GO:0030901; GO:0030902; GO:0030917; GO:0034672; GO:0035775; GO:0043049; GO:0043565; GO:0048596; GO:0048793; GO:0048856; GO:0060113; GO:0060118; GO:0060271; GO:0072114 13464 XR_006395490.1 6 23 7 31 39 NA NA NA NA NA NA 13465 XR_006391498.1 5 126 51 217 40 NA NA NA NA NA NA 13466 XM_029348610.2 425 103 243 549 558 NA NA NA NA NA NA 13467 XM_044314297.1 2 26 7 4 26 NA NA NA NA NA NA 13468 XM_044322741.1 2 0 0 36 9 NA NA NA NA NA NA 13469 XM_044312717.1 1162 1221 1026 1496 1587 NA NA NA NA NA NA 13470 XM_044321884.1 430 253 159 359 423 A7SPW6 6.2e-100 Elongation factor Ts, mitochondrial (EF-Ts) (EF-TsMt) Nematostella vectensis (Starlet sea anemone) mitochondrial translational elongation [GO:0070125]; translational elongation [GO:0006414] GO:0003746; GO:0005759; GO:0006414; GO:0070125 13471 XM_044314697.1 9 28 5 36 45 Q7TSF2 3.59e-114 Vesicular glutamate transporter 3 (VGluT3) (Solute carrier family 17 member 8) Rattus norvegicus (Rat) anion transport [GO:0006820]; brain development [GO:0007420]; cochlea development [GO:0090102]; L-glutamate import [GO:0051938]; L-glutamate transmembrane transport [GO:0015813]; neural retina development [GO:0003407]; neurotransmitter loading into synaptic vesicle [GO:0098700]; phosphate ion homeostasis [GO:0055062]; positive regulation of glutamate uptake involved in transmission of nerve impulse [GO:0051951]; regulation of acetylcholine uptake [GO:0051631]; regulation of synapse structure or activity [GO:0050803]; sensory perception of sound [GO:0007605]; sodium-dependent phosphate transport [GO:0044341]; synaptic transmission, glutamatergic [GO:0035249] GO:0003407; GO:0005254; GO:0005313; GO:0005326; GO:0005436; GO:0005737; GO:0005771; GO:0005886; GO:0006820; GO:0007420; GO:0007605; GO:0008021; GO:0015813; GO:0016020; GO:0022857; GO:0030425; GO:0030672; GO:0031410; GO:0034707; GO:0035249; GO:0043025; GO:0043204; GO:0043679; GO:0044341; GO:0045202; GO:0050803; GO:0051631; GO:0051938; GO:0051951; GO:0055062; GO:0060076; GO:0090102; GO:0097440; GO:0097441; GO:0097451; GO:0098700; GO:0140788; GO:1990030 13472 XM_044318595.1 952 812 714 898 1007 Q3UR70 0 Transforming growth factor-beta receptor-associated protein 1 (TGF-beta receptor-associated protein 1) (TRAP-1) (TRAP1) Mus musculus (Mouse) autophagy [GO:0006914]; endosomal vesicle fusion [GO:0034058]; endosome to lysosome transport [GO:0008333]; intracellular protein transport [GO:0006886]; regulation of DNA-templated transcription [GO:0006355]; signal transduction [GO:0007165] GO:0005160; GO:0005737; GO:0005769; GO:0006355; GO:0006886; GO:0006914; GO:0007165; GO:0008333; GO:0016020; GO:0033263; GO:0034058; GO:0043231; GO:0046332 13473 XR_003826702.2 79 80 49 44 136 NA NA NA NA NA NA 13474 XM_044319221.1 1804 953 799 1117 907 Q503Z8 7.58e-47 NA NA NA NA 13475 XM_044311438.1 54 3 40 9 8 NA NA NA NA NA NA 13476 XM_044311997.1 8 0 0 3 0 NA NA NA NA NA NA 13477 XR_006395552.1 212 262 200 270 267 NA NA NA NA NA NA 13478 XM_029357368.2 1151 595 1193 871 755 NA NA NA NA NA NA 13479 XM_029337390.2 2213 716 668 895 1043 Q16959 0 Dynein intermediate chain 2, ciliary Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina) NA GO:0005737; GO:0005874; GO:0005929; GO:0030286 13480 XR_006393062.1 41 2 25 5 151 NA NA NA NA NA NA 13481 XM_029335472.2 137 199 102 79 44 NA NA NA NA NA NA 13482 XR_006398122.1 894 1326 935 776 552 NA NA NA NA NA NA 13483 XM_029356137.2 41 30 6 51 165 NA NA NA NA NA NA 13484 XM_029333296.2 85 0 34 22 96 Q96AY4 3.74e-138 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13485 XM_029333296.2 85 0 34 22 96 Q96AY4 3.48e-130 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13486 XM_029333296.2 85 0 34 22 96 Q96AY4 7e-107 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13487 XM_029333296.2 85 0 34 22 96 Q96AY4 1.1e-69 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13488 XM_029333296.2 85 0 34 22 96 Q96AY4 1.31e-37 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13489 XM_029333296.2 85 0 34 22 96 Q96AY4 6.12e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13490 XM_029344906.2 253 91 35 208 206 Q9Y5X5 7.88e-23 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (G-protein coupled receptor HLWAR77) (Neuropeptide G-protein coupled receptor) Homo sapiens (Human) detection of abiotic stimulus [GO:0009582]; G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0009582; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 13491 XM_044317534.1 0 0 2 0 8 NA NA NA NA NA NA 13492 XM_044315232.1 3677 3223 2532 2247 3278 Q567Y6 2.7e-62 Intraflagellar transport protein 22 homolog (Rab-like protein 5) Danio rerio (Zebrafish) (Brachydanio rerio) intracellular protein transport [GO:0006886] GO:0003924; GO:0005525; GO:0006886; GO:0012505; GO:0030992 13493 XR_006396272.1 177 278 237 153 348 NA NA NA NA NA NA 13494 XM_044309526.1 184 72 0 0 227 P35556 6.6e-29 Fibrillin-2 [Cleaved into: Placensin] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030023; GO:0030326; GO:0030501; GO:0031012; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 13495 XM_044309526.1 184 72 0 0 227 P35556 5.36e-25 Fibrillin-2 [Cleaved into: Placensin] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030023; GO:0030326; GO:0030501; GO:0031012; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 13496 XM_044309526.1 184 72 0 0 227 P35556 3.92e-24 Fibrillin-2 [Cleaved into: Placensin] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030023; GO:0030326; GO:0030501; GO:0031012; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 13497 XM_044324461.1 46 30 16 129 89 NA NA NA NA NA NA 13498 XM_029331842.2 265 56 41 201 205 Q5RJA1 0 DNA-binding protein RFX6 (Regulatory factor X 6) Danio rerio (Zebrafish) (Brachydanio rerio) endocrine pancreas development [GO:0031018]; glucose homeostasis [GO:0042593]; pancreatic A cell differentiation [GO:0003310]; pancreatic D cell differentiation [GO:0003311]; pancreatic epsilon cell differentiation [GO:0090104]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of insulin secretion [GO:0050796]; regulation of transcription by RNA polymerase II [GO:0006357]; type B pancreatic cell differentiation [GO:0003309] GO:0000976; GO:0000978; GO:0000981; GO:0003309; GO:0003310; GO:0003311; GO:0005634; GO:0006357; GO:0031018; GO:0035774; GO:0042593; GO:0045893; GO:0045944; GO:0050796; GO:0090104 13499 XM_029332699.2 5823 6925 4608 6244 6686 Q8R1V4 6.64e-115 Transmembrane emp24 domain-containing protein 4 (Endoplasmic reticulum stress-response protein 25) (ERS25) (p24 family protein alpha-3) (p24alpha3) (p26) Mus musculus (Mouse) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886] GO:0005783; GO:0005789; GO:0005793; GO:0005794; GO:0006886; GO:0006888; GO:0007030; GO:0030134 13500 XM_044312334.1 0 1 0 0 9 NA NA NA NA NA NA 13501 XM_029356336.2 100 0 212 61 70 Q68EH9 5.67e-121 Protein cereblon (zcrbn) Danio rerio (Zebrafish) (Brachydanio rerio) cell population proliferation [GO:0008283]; embryonic pectoral fin morphogenesis [GO:0035118]; fin development [GO:0033333]; limb development [GO:0060173]; otic vesicle development [GO:0071599]; otic vesicle morphogenesis [GO:0071600]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567] GO:0000151; GO:0005634; GO:0005737; GO:0008283; GO:0016567; GO:0031464; GO:0033333; GO:0035118; GO:0043161; GO:0046872; GO:0060173; GO:0071599; GO:0071600 13502 XM_044323947.1 79 257 125 195 213 Q9CXI3 4.71e-128 DBH-like monooxygenase protein 1 (EC 1.14.17.-) (DBH-related protein) (Monooxygenase X) Mus musculus (Mouse) dopamine catabolic process [GO:0042420]; norepinephrine biosynthetic process [GO:0042421]; octopamine biosynthetic process [GO:0006589] GO:0004500; GO:0005507; GO:0005615; GO:0005789; GO:0006589; GO:0030667; GO:0042420; GO:0042421 13503 XM_044315044.1 0 0 0 0 11 NA NA NA NA NA NA 13504 XR_006395246.1 33 21 14 26 63 NA NA NA NA NA NA 13505 XM_044326883.1 0 6 0 0 0 NA NA NA NA NA NA 13506 XM_029339876.2 2381 2071 1438 1786 1699 Q78KK3 1.71e-75 Solute carrier family 22 member 18 (Imprinted multi-membrane-spanning polyspecific transporter-related protein 1) (Multi-membrane-spanning polyspecific transporter) (Organic cation transporter-like protein 2) (ORCTL-2) Mus musculus (Mouse) anion transport [GO:0006820]; xenobiotic detoxification by transmembrane export across the plasma membrane [GO:1990961]; xenobiotic transport [GO:0042908] GO:0005635; GO:0005737; GO:0005886; GO:0006820; GO:0008514; GO:0015293; GO:0016324; GO:0031625; GO:0042908; GO:1990961 13507 XM_029338554.2 77 99 28 28 161 NA NA NA NA NA NA 13508 XM_044311130.1 10 0 0 10 0 Q09575 3.28e-46 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 13509 XM_044322226.1 80 10 57 144 385 NA NA NA NA NA NA 13510 XM_044323622.1 2 0 4 17 21 A0A1B0GUU1 6.47e-27 Uncharacterized protein C17orf113 Homo sapiens (Human) NA NA 13511 XM_029343393.2 434 168 48 325 354 NA NA NA NA NA NA 13512 XM_044313700.1 107 21 53 41 112 NA NA NA NA NA NA 13513 XM_044327658.1 118 70 71 312 291 Q96AY4 7.53e-180 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13514 XM_044327658.1 118 70 71 312 291 Q96AY4 1.36e-167 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13515 XM_044327658.1 118 70 71 312 291 Q96AY4 1.19e-129 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13516 XM_029358251.2 0 42 7 0 0 NA NA NA NA NA NA 13517 XM_029328661.2 1342 1244 1206 1393 2115 Q11126 2.84e-43 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3 (EC 2.4.1.65) (4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase) (EC 2.4.1.152) (Alpha-3-fucosyltransferase FUT3) (EC 2.4.1.-) (Blood group Lewis alpha-4-fucosyltransferase) (Lewis FT) (FUTB) (Fucosyltransferase 3) (Fucosyltransferase III) (FucT-III) Bos taurus (Bovine) fucosylation [GO:0036065]; lipid metabolic process [GO:0006629]; oligosaccharide metabolic process [GO:0009311]; positive regulation of cell-cell adhesion [GO:0022409]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127] GO:0006487; GO:0006493; GO:0006629; GO:0009311; GO:0017060; GO:0017083; GO:0022409; GO:0030334; GO:0032580; GO:0036065; GO:0042127; GO:0046920 13518 XM_044309544.1 102 31 86 44 223 NA NA NA NA NA NA 13519 XM_044324799.1 18 18 30 16 64 NA NA NA NA NA NA 13520 XM_044329198.1 1230 844 916 1835 1378 Q8TDJ6 0 DmX-like protein 2 (Rabconnectin-3) Homo sapiens (Human) vacuolar acidification [GO:0007035] GO:0005615; GO:0007035; GO:0008021; GO:0030672; GO:0031267; GO:0043291; GO:0098992 13521 XM_044308275.1 6425 5474 3514 4412 2687 Q6P8Y1 2.24e-64 Calcyphosin-like protein Mus musculus (Mouse) NA GO:0005509; GO:0005737 13522 XM_044307103.1 6 0 0 0 0 Q58DM8 1.56e-122 Enoyl-CoA hydratase, mitochondrial (mECH) (mECH1) (EC 4.2.1.17) (EC 5.3.3.8) (Enoyl-CoA hydratase 1) (ECHS1) (Short-chain enoyl-CoA hydratase) (SCEH) Bos taurus (Bovine) fatty acid beta-oxidation [GO:0006635] GO:0004165; GO:0004300; GO:0005739; GO:0005759; GO:0006635; GO:0043956; GO:0120092 13523 XR_003825711.2 173 96 91 179 414 NA NA NA NA NA NA 13524 XM_044320341.1 0 0 0 289 21 P16157 2.45e-94 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 13525 XM_044320341.1 0 0 0 289 21 P16157 1.55e-88 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 13526 XM_029350148.2 2312 2009 2766 3569 3576 Q9UHB7 3.19e-47 AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31 protein) (Protein AF-5q31) (Major CDK9 elongation factor-associated protein) Homo sapiens (Human) regulation of gene expression [GO:0010468]; spermatid development [GO:0007286] GO:0000791; GO:0001650; GO:0005654; GO:0007286; GO:0008023; GO:0010468; GO:0032783 13527 XM_029351210.2 131 0 0 10 5 NA NA NA NA NA NA 13528 XM_029327407.2 595 379 178 494 401 NA NA NA NA NA NA 13529 XM_029348522.2 30 0 14 0 18 NA NA NA NA NA NA 13530 XM_044315006.1 3 0 0 0 7 NA NA NA NA NA NA 13531 XM_029327031.2 0 0 0 0 188 Q8R4K8 0 Pappalysin-1 (EC 3.4.24.79) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase) (Pregnancy-associated plasma protein A) (PAPP-A) Mus musculus (Mouse) cell surface receptor signaling pathway [GO:0007166]; female pregnancy [GO:0007565]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to dexamethasone [GO:0071548]; response to follicle-stimulating hormone [GO:0032354] GO:0004175; GO:0004222; GO:0005576; GO:0005615; GO:0006508; GO:0007166; GO:0007565; GO:0008237; GO:0030163; GO:0032354; GO:0046872; GO:0071548 13532 XM_029344261.2 37 10 39 4 39 Q6AZN6 0 Phosphatidylinositol 3-kinase catalytic subunit type 3 (PI3-kinase type 3) (PI3K type 3) (PtdIns-3-kinase type 3) (EC 2.7.1.137) (Phosphoinositide-3-kinase class 3) Xenopus laevis (African clawed frog) autophagy [GO:0006914]; cell cycle [GO:0007049]; cell division [GO:0051301]; phosphatidylinositol-mediated signaling [GO:0048015]; phosphorylation [GO:0016310]; regulation of cytokinesis [GO:0032465] GO:0005524; GO:0006914; GO:0007049; GO:0016303; GO:0016310; GO:0030496; GO:0032465; GO:0048015; GO:0051301 13533 XR_006396599.1 468 558 253 597 538 NA NA NA NA NA NA 13534 XM_044311480.1 224 109 83 257 312 NA NA NA NA NA NA 13535 XM_044315554.1 56 60 52 97 94 NA NA NA NA NA NA 13536 XM_044316190.1 0 0 7 10 0 NA NA NA NA NA NA 13537 XR_006392444.1 276 278 66 185 59 Q99570 1.17e-23 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 13538 XM_029357018.2 304 204 227 351 0 NA NA NA NA NA NA 13539 XM_044307287.1 0 6 0 0 0 D2IYS2 8.96e-65 Tyrosine-protein kinase receptor torso (EC 2.7.10.1) Bombyx mori (Silk moth) NA GO:0004714; GO:0005524; GO:0005886; GO:0046872 13540 XR_006397271.1 66 21 48 30 11 NA NA NA NA NA NA 13541 XM_029337335.2 632 578 540 1032 1618 O42115 1.61e-28 Aristaless-related homeobox protein (ARX) Danio rerio (Zebrafish) (Brachydanio rerio) enteric nervous system development [GO:0048484]; neuron development [GO:0048666]; pancreatic A cell development [GO:0003322]; regulation of transcription by RNA polymerase II [GO:0006357]; subthalamus development [GO:0021539]; telencephalon development [GO:0021537]; thalamus development [GO:0021794] GO:0000977; GO:0000981; GO:0003322; GO:0005634; GO:0006357; GO:0021537; GO:0021539; GO:0021794; GO:0048484; GO:0048666 13542 XM_029331719.2 82 94 43 30 29 NA NA NA NA NA NA 13543 XM_029340106.2 738 462 433 915 454 O74212 4.15e-142 Acyl-lipid (8-3)-desaturase (EC 1.14.19.30) (Delta(5) fatty acid desaturase) (Delta-5 fatty acid desaturase) Mortierella alpina (Oleaginous fungus) (Mortierella renispora) fatty acid biosynthetic process [GO:0006633] GO:0006633; GO:0016020; GO:0020037; GO:0046872; GO:0102866 13544 XR_003824218.2 12 27 9 2 0 NA NA NA NA NA NA 13545 XM_029345607.2 609 1039 669 592 258 O14662 3.44e-87 Syntaxin-16 (Syn16) Homo sapiens (Human) endocytic recycling [GO:0032456]; intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]; vesicle docking [GO:0048278]; vesicle fusion [GO:0006906] GO:0000139; GO:0000149; GO:0005484; GO:0005737; GO:0005794; GO:0005802; GO:0005829; GO:0005925; GO:0006886; GO:0006906; GO:0012505; GO:0016020; GO:0019905; GO:0030672; GO:0031201; GO:0031985; GO:0032456; GO:0032588; GO:0042147; GO:0043231; GO:0048278; GO:0048471 13546 XM_044316844.1 190 119 0 172 161 NA NA NA NA NA NA 13547 XM_029326972.2 6 5 0 3 0 NA NA NA NA NA NA 13548 XM_044309712.1 15 39 6 0 4 NA NA NA NA NA NA 13549 XM_044317002.1 31 1 11 0 27 NA NA NA NA NA NA 13550 XM_029356175.2 4833 5528 3416 4662 3488 P50538 3.69e-21 Max dimerization protein 1 (Max dimerizer 1) (Protein MAD) Mus musculus (Mouse) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000785; GO:0000978; GO:0000981; GO:0001227; GO:0005654; GO:0005739; GO:0005829; GO:0006357; GO:0046983; GO:0070443 13551 XM_029355146.2 17 0 0 0 0 NA NA NA NA NA NA 13552 XM_044324977.1 33 30 6 62 102 NA NA NA NA NA NA 13553 XM_044321573.1 1412 1808 332 1138 1723 NA NA NA NA NA NA 13554 XM_044322465.1 201 77 65 116 45 Q96AY4 4.87e-82 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13555 XM_044322465.1 201 77 65 116 45 Q96AY4 1.14e-80 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13556 XM_044322465.1 201 77 65 116 45 Q96AY4 5.11e-77 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13557 XM_044322465.1 201 77 65 116 45 Q96AY4 8.27e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13558 XM_044322465.1 201 77 65 116 45 Q96AY4 1.73e-62 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13559 XM_044322465.1 201 77 65 116 45 Q96AY4 1.08e-49 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13560 XM_029329464.2 0 0 0 225 136 Q13118 1.23e-58 Krueppel-like factor 10 (EGR-alpha) (Transforming growth factor-beta-inducible early growth response protein 1) (TGFB-inducible early growth response protein 1) (TIEG-1) Homo sapiens (Human) bone mineralization [GO:0030282]; cell-cell signaling [GO:0007267]; cellular response to starvation [GO:0009267]; circadian rhythm [GO:0007623]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of circadian rhythm [GO:0042752]; regulation of transcription by RNA polymerase II [GO:0006357]; somatic stem cell population maintenance [GO:0035019] GO:0000122; GO:0000785; GO:0000978; GO:0000981; GO:0001046; GO:0001228; GO:0003700; GO:0005634; GO:0006357; GO:0007267; GO:0007623; GO:0008285; GO:0009267; GO:0030282; GO:0035019; GO:0042752; GO:0045672; GO:0045892; GO:0045944; GO:0046872; GO:1990837 13561 XM_029353932.2 133 0 0 0 0 D3Z5L6 3.14e-59 MFS-type transporter SLC18B1 (Solute carrier family 18 member B1) (Vesicular polyamine transporter) (VPAT) Mus musculus (Mouse) serotonin transport [GO:0006837]; serotonin uptake [GO:0051610]; spermidine transport [GO:0015848]; spermine transport [GO:0000296] GO:0000296; GO:0006837; GO:0015311; GO:0015312; GO:0015848; GO:0022857; GO:0030667; GO:0030672; GO:0051610 13562 XM_044325094.1 56 104 74 359 228 NA NA NA NA NA NA 13563 XM_029347597.2 32 10 24 46 51 NA NA NA NA NA NA 13564 XM_044309483.1 4 8 6 4 32 NA NA NA NA NA NA 13565 XM_029341756.2 131 129 111 62 88 Q6GPE5 2.25e-142 Protein fem-1 homolog B (FEM1b) (FEM1-beta) Xenopus laevis (African clawed frog) apoptotic process [GO:0006915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of DNA damage checkpoint [GO:2000001]; ubiquitin-dependent protein catabolic process via the C-end degron rule pathway [GO:0140627] GO:0005634; GO:0005737; GO:0006915; GO:0016567; GO:0031462; GO:0043161; GO:0140627; GO:1990756; GO:2000001 13566 XM_029338034.2 388 601 412 361 352 NA NA NA NA NA NA 13567 XR_006393342.1 29 5 17 25 6 NA NA NA NA NA NA 13568 XM_029343149.2 453 513 460 405 698 NA NA NA NA NA NA 13569 XM_044320117.1 297 222 333 313 535 Q6Y5D8 7.46e-51 Rho GTPase-activating protein 10 (PH and SH3 domain-containing rhoGAP protein) (PS-GAP) (PSGAP) (Rho-type GTPase-activating protein 10) Mus musculus (Mouse) cytoskeleton organization [GO:0007010]; negative regulation of apoptotic process [GO:0043066]; signal transduction [GO:0007165] GO:0005096; GO:0005829; GO:0005886; GO:0007010; GO:0007165; GO:0043066; GO:0048471 13570 XR_006391310.1 2 0 0 0 12 NA NA NA NA NA NA 13571 XM_029333853.2 56 0 87 158 0 Q8K4J6 1.92e-25 Myocardin-related transcription factor A (MRTF-A) (Basic SAP coiled-coil transcription activator) (MKL/myocardin-like protein 1) (Megakaryoblastic leukemia 1 protein homolog) (Megakaryocytic acute leukemia protein homolog) Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; forebrain development [GO:0030900]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; smooth muscle cell differentiation [GO:0051145]; wound healing, spreading of cells [GO:0044319] GO:0000976; GO:0001764; GO:0003700; GO:0003713; GO:0003779; GO:0003785; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006357; GO:0030036; GO:0030900; GO:0031175; GO:0043154; GO:0043522; GO:0044319; GO:0045893; GO:0045944; GO:0051145; GO:0060090; GO:1902895; GO:2001234 13572 XM_044310272.1 97 34 65 33 29 NA NA NA NA NA NA 13573 XM_029338332.2 20 12 3 36 19 NA NA NA NA NA NA 13574 XM_044329127.1 19 8 10 61 8 Q8BJQ2 7.07e-46 Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.4.19.12) (Deubiquitinating enzyme 1) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) [Cleaved into: Ubiquitin carboxyl-terminal hydrolase 1, N-terminal fragment] Mus musculus (Mouse) DNA repair [GO:0006281]; monoubiquitinated protein deubiquitination [GO:0035520]; protein deubiquitination [GO:0016579]; regulation of DNA repair [GO:0006282]; response to UV [GO:0009411]; skeletal system development [GO:0001501]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0001501; GO:0004197; GO:0004843; GO:0005634; GO:0005654; GO:0005829; GO:0006281; GO:0006282; GO:0006511; GO:0008233; GO:0009411; GO:0016579; GO:0035520 13575 XR_003825422.2 13 3 68 1 3 NA NA NA NA NA NA 13576 XR_006397826.1 1 20 17 2 28 NA NA NA NA NA NA 13577 XM_044313807.1 67 13 15 56 30 Q8D3M4 1.74e-95 2-aminoethylphosphonate--pyruvate transaminase (EC 2.6.1.37) (2-aminoethylphosphonate aminotransferase) (AEP transaminase) (AEPT) Vibrio vulnificus (strain CMCP6) organic phosphonate catabolic process [GO:0019700] GO:0019700; GO:0047304 13578 XM_029358607.2 9 55 12 13 11 P35067 4.28e-59 Histone H2B Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 13579 XM_044326910.1 819 816 560 70 0 NA NA NA NA NA NA 13580 XM_029342538.2 257 231 249 153 105 NA NA NA NA NA NA 13581 XM_044320150.1 32 7 11 29 6 P70531 6.15e-128 Eukaryotic elongation factor 2 kinase (eEF-2 kinase) (eEF-2K) (EC 2.7.11.20) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase) Rattus norvegicus (Rat) cellular response to anoxia [GO:0071454]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to insulin stimulus [GO:0032869]; negative regulation of apoptotic process [GO:0043066]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of endocytosis [GO:0045807]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; regulation of protein autophosphorylation [GO:0031952]; regulation of translation at postsynapse [GO:0140245]; response to ischemia [GO:0002931]; response to prolactin [GO:1990637] GO:0002931; GO:0004674; GO:0004686; GO:0005509; GO:0005516; GO:0005524; GO:0014069; GO:0031952; GO:0032869; GO:0043066; GO:0043197; GO:0045182; GO:0045807; GO:0046777; GO:0051965; GO:0061003; GO:0071277; GO:0071320; GO:0071454; GO:0098978; GO:0140245; GO:1990416; GO:1990637 13582 XM_044320150.1 32 7 11 29 6 P70531 1.6e-42 Eukaryotic elongation factor 2 kinase (eEF-2 kinase) (eEF-2K) (EC 2.7.11.20) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase) Rattus norvegicus (Rat) cellular response to anoxia [GO:0071454]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to insulin stimulus [GO:0032869]; negative regulation of apoptotic process [GO:0043066]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of endocytosis [GO:0045807]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; regulation of protein autophosphorylation [GO:0031952]; regulation of translation at postsynapse [GO:0140245]; response to ischemia [GO:0002931]; response to prolactin [GO:1990637] GO:0002931; GO:0004674; GO:0004686; GO:0005509; GO:0005516; GO:0005524; GO:0014069; GO:0031952; GO:0032869; GO:0043066; GO:0043197; GO:0045182; GO:0045807; GO:0046777; GO:0051965; GO:0061003; GO:0071277; GO:0071320; GO:0071454; GO:0098978; GO:0140245; GO:1990416; GO:1990637 13583 XM_044313550.1 93 54 15 53 95 Q0R4F1 1.97e-38 ATP-dependent DNA helicase PIF1 (EC 3.6.4.12) (DNA repair and recombination helicase PIF1) Xenopus laevis (African clawed frog) DNA recombination [GO:0006310]; DNA repair [GO:0006281]; mitochondrial genome maintenance [GO:0000002]; telomere maintenance [GO:0000723] GO:0000002; GO:0000723; GO:0003677; GO:0005524; GO:0005634; GO:0005739; GO:0006281; GO:0006310; GO:0016887; GO:0043139 13584 XM_029325534.2 1391 1136 650 1441 1347 Q5R9I6 0 26S proteasome non-ATPase regulatory subunit 2 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) regulation of protein catabolic process [GO:0042176] GO:0005838; GO:0022624; GO:0030234; GO:0042176 13585 XM_044315097.1 1183 613 546 1046 797 O60308 0 Centrosomal protein of 104 kDa (Cep104) Homo sapiens (Human) NA GO:0000922; GO:0005737; GO:0005814; GO:0005929; GO:0016594; GO:0016595; GO:0016596 13586 XM_029351746.2 0 0 0 0 51 NA NA NA NA NA NA 13587 XM_044311562.1 0 3 13 5 36 NA NA NA NA NA NA 13588 XM_029338139.2 112 49 28 71 89 NA NA NA NA NA NA 13589 XM_044314125.1 31 2 0 49 39 NA NA NA NA NA NA 13590 XM_029332869.2 184 99 93 64 292 NA NA NA NA NA NA 13591 XM_029331537.2 490 258 229 199 821 NA NA NA NA NA NA 13592 XM_044321188.1 0 4 7 1 4 NA NA NA NA NA NA 13593 XM_044325057.1 45 15 0 0 66 NA NA NA NA NA NA 13594 XM_044313490.1 60 2 24 17 38 NA NA NA NA NA NA 13595 XM_029328786.2 176 104 171 163 245 Q3B7D3 1.59e-33 Tectonic-2 Rattus norvegicus (Rat) cilium assembly [GO:0060271]; protein localization to ciliary transition zone [GO:1904491]; smoothened signaling pathway [GO:0007224] GO:0005737; GO:0005856; GO:0007224; GO:0016020; GO:0035869; GO:0036038; GO:0060271; GO:1904491 13596 XM_029337898.2 0 105 0 130 246 NA NA NA NA NA NA 13597 XM_029335772.2 239 103 75 137 171 O88451 1.55e-78 Retinol dehydrogenase 7 (EC 1.1.1.105) (Cis-retinol/3alpha-hydroxysterol short-chain dehydrogenase isozyme 2) (Cis-retinol/androgen dehydrogenase type 2) (CRAD-2) Mus musculus (Mouse) retinol metabolic process [GO:0042572]; steroid metabolic process [GO:0008202] GO:0003824; GO:0004745; GO:0005783; GO:0008202; GO:0016491; GO:0042572; GO:0043231; GO:0047023; GO:0047044 13598 XM_029356123.2 1274 1134 1115 1351 1831 NA NA NA NA NA NA 13599 XM_029331516.2 656 194 222 385 400 O15315 1.11e-121 DNA repair protein RAD51 homolog 2 (R51H2) (RAD51 homolog B) (Rad51B) (RAD51-like protein 1) Homo sapiens (Human) blastocyst growth [GO:0001832]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; reciprocal meiotic recombination [GO:0007131]; somite development [GO:0061053] GO:0000724; GO:0001832; GO:0003677; GO:0003690; GO:0003697; GO:0005524; GO:0005634; GO:0005654; GO:0005657; GO:0006281; GO:0006310; GO:0007131; GO:0008094; GO:0008284; GO:0010971; GO:0033063; GO:0061053; GO:0140664 13600 XM_029327147.2 174 0 0 0 0 P43140 2e-28 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) Rattus norvegicus (Rat) activation of phospholipase C activity [GO:0007202]; adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; adrenergic receptor signaling pathway [GO:0071875]; adult heart development [GO:0007512]; aging [GO:0007568]; calcium ion transport into cytosol [GO:0060402]; cell growth involved in cardiac muscle cell development [GO:0061049]; cell-cell signaling [GO:0007267]; MAPK cascade [GO:0000165]; micturition [GO:0060073]; multicellular organism aging [GO:0010259]; negative regulation of autophagy [GO:0010507]; negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure [GO:0001985]; negative regulation of Rho protein signal transduction [GO:0035024]; neuron-glial cell signaling [GO:0150099]; norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001994]; organ growth [GO:0035265]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; pilomotor reflex [GO:0097195]; positive regulation of action potential [GO:0045760]; positive regulation of cardiac muscle contraction [GO:0060452]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of heart rate [GO:0010460]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; positive regulation of systemic arterial blood pressure [GO:0003084]; positive regulation of the force of heart contraction by epinephrine-norepinephrine [GO:0001997]; positive regulation of vasoconstriction [GO:0045907]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of blood pressure [GO:0008217]; response to hormone [GO:0009725]; response to xenobiotic stimulus [GO:0009410] GO:0000165; GO:0001985; GO:0001994; GO:0001996; GO:0001997; GO:0003084; GO:0004930; GO:0004937; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0005901; GO:0007200; GO:0007202; GO:0007204; GO:0007267; GO:0007512; GO:0007568; GO:0008217; GO:0009410; GO:0009725; GO:0010259; GO:0010460; GO:0010507; GO:0010613; GO:0016020; GO:0030018; GO:0030315; GO:0031965; GO:0032230; GO:0035024; GO:0035265; GO:0042734; GO:0043410; GO:0045211; GO:0045760; GO:0045907; GO:0045987; GO:0046982; GO:0060073; GO:0060402; GO:0060452; GO:0061049; GO:0070374; GO:0071875; GO:0071880; GO:0090037; GO:0097195; GO:0098691; GO:0098978; GO:0098982; GO:0099171; GO:0150099; GO:1903997 13601 XR_006391601.1 58 14 49 49 133 P48547 4.07e-77 Potassium voltage-gated channel subfamily C member 1 (NGK2) (Voltage-gated potassium channel subunit Kv3.1) (Voltage-gated potassium channel subunit Kv4) Homo sapiens (Human) cellular response to xenobiotic stimulus [GO:0071466]; cerebellum development [GO:0021549]; corpus callosum development [GO:0022038]; globus pallidus development [GO:0021759]; optic nerve development [GO:0021554]; positive regulation of voltage-gated potassium channel activity [GO:1903818]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; protein tetramerization [GO:0051262]; response to amine [GO:0014075]; response to auditory stimulus [GO:0010996]; response to fibroblast growth factor [GO:0071774]; response to light intensity [GO:0009642]; response to nerve growth factor [GO:1990089]; response to potassium ion [GO:0035864]; response to toxic substance [GO:0009636] GO:0005249; GO:0005251; GO:0005886; GO:0006813; GO:0008076; GO:0009636; GO:0009642; GO:0009986; GO:0010996; GO:0014075; GO:0016020; GO:0019894; GO:0021549; GO:0021554; GO:0021759; GO:0022038; GO:0030424; GO:0030673; GO:0032590; GO:0032809; GO:0035864; GO:0042734; GO:0044305; GO:0044325; GO:0045211; GO:0051260; GO:0051262; GO:0071466; GO:0071774; GO:0071805; GO:0099508; GO:1903818; GO:1990089 13602 XM_029357048.2 2852 3056 1270 3246 2132 P48734 5.07e-148 Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase) Bos taurus (Bovine) apoptotic process [GO:0006915]; cell division [GO:0051301]; epithelial cell differentiation [GO:0030855]; fibroblast proliferation [GO:0048144]; G2/M transition of mitotic cell cycle [GO:0000086]; Golgi disassembly [GO:0090166]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; negative regulation of apoptotic process [GO:0043066]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of mitochondrial ATP synthesis coupled electron transport [GO:1905448]; positive regulation of protein localization to nucleus [GO:1900182]; protein localization to kinetochore [GO:0034501]; protein phosphorylation [GO:0006468]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511] GO:0000086; GO:0003682; GO:0004674; GO:0004693; GO:0005524; GO:0005634; GO:0005654; GO:0005759; GO:0005813; GO:0005829; GO:0005876; GO:0006468; GO:0006915; GO:0007095; GO:0008353; GO:0010971; GO:0018105; GO:0018107; GO:0030332; GO:0030496; GO:0030544; GO:0030855; GO:0034501; GO:0035173; GO:0042752; GO:0043066; GO:0048144; GO:0048511; GO:0051301; GO:0072686; GO:0090166; GO:0097125; GO:0106310; GO:1900182; GO:1905448 13603 XM_044321085.1 0 0 51 0 0 Q9NZJ4 0 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 13604 XM_044311656.1 28 7 45 1 0 B8VIU6 2.75e-63 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 13605 XM_029336971.2 144 325 154 856 673 P51869 6.95e-107 Cytochrome P450 4F4 (CYPIVF4) (Leukotriene-B4 20-monooxygenase) (EC 1.14.14.94) Rattus norvegicus (Rat) arachidonic acid metabolic process [GO:0019369]; leukotriene B4 catabolic process [GO:0036101]; menaquinone catabolic process [GO:0042361]; omega-hydroxylase P450 pathway [GO:0097267]; phylloquinone catabolic process [GO:0042376]; prostaglandin catabolic process [GO:1905344] GO:0005506; GO:0005789; GO:0008391; GO:0019369; GO:0020037; GO:0036101; GO:0042361; GO:0042376; GO:0043231; GO:0050051; GO:0097267; GO:1905344 13606 XM_044320104.1 24 10 1 6 24 NA NA NA NA NA NA 13607 XM_029345252.2 2696 5380 3280 2325 1805 NA NA NA NA NA NA 13608 XM_029342550.2 0 32 0 0 0 Q9D0B6 1.44e-45 Protein PBDC1 (Polysaccharide biosynthesis domain-containing protein 1) Mus musculus (Mouse) NA NA 13609 XM_029327713.2 2898 1908 1405 2400 2689 Q641Y2 0 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (EC 7.1.1.2) (Complex I-49kD) (CI-49kD) (NADH-ubiquinone oxidoreductase 49 kDa subunit) Rattus norvegicus (Rat) cellular response to oxygen levels [GO:0071453]; gliogenesis [GO:0042063]; mitochondrial ATP synthesis coupled electron transport [GO:0042775]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrial respiratory chain complex I assembly [GO:0032981]; neural precursor cell proliferation [GO:0061351]; neurogenesis [GO:0022008]; response to oxidative stress [GO:0006979] GO:0005654; GO:0005743; GO:0005747; GO:0006120; GO:0006979; GO:0008137; GO:0019826; GO:0022008; GO:0031625; GO:0032981; GO:0042063; GO:0042775; GO:0046872; GO:0048038; GO:0051287; GO:0051539; GO:0061351; GO:0071453 13610 XR_006397561.1 157 0 116 34 355 NA NA NA NA NA NA 13611 XR_006393505.1 31 22 11 30 4 NA NA NA NA NA NA 13612 XM_029356337.2 529 298 231 506 435 Q68EH9 2.6e-125 Protein cereblon (zcrbn) Danio rerio (Zebrafish) (Brachydanio rerio) cell population proliferation [GO:0008283]; embryonic pectoral fin morphogenesis [GO:0035118]; fin development [GO:0033333]; limb development [GO:0060173]; otic vesicle development [GO:0071599]; otic vesicle morphogenesis [GO:0071600]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567] GO:0000151; GO:0005634; GO:0005737; GO:0008283; GO:0016567; GO:0031464; GO:0033333; GO:0035118; GO:0043161; GO:0046872; GO:0060173; GO:0071599; GO:0071600 13613 XM_029330105.2 468 212 244 522 420 Q8C079 0 Striatin-interacting protein 1 (Protein FAM40A) Mus musculus (Mouse) cortical actin cytoskeleton organization [GO:0030866]; cytoskeleton organization [GO:0007010]; regulation of cell morphogenesis [GO:0022604] GO:0005634; GO:0005829; GO:0007010; GO:0019901; GO:0022604; GO:0030866; GO:0031267 13614 XM_029355759.2 28 16 5 33 7 Q8N539 2.03e-67 Fibrinogen C domain-containing protein 1 Homo sapiens (Human) cell adhesion [GO:0007155] GO:0005102; GO:0005615; GO:0007155; GO:0008061; GO:0016020; GO:0046872; GO:0062023 13615 XM_029356818.2 56 156 53 75 242 Q9JHA8 5.11e-61 von Willebrand factor A domain-containing protein 7 (Protein G7c) Mus musculus (Mouse) NA GO:0005576 13616 XR_003826616.2 29 72 44 31 84 NA NA NA NA NA NA 13617 XM_044312817.1 100 96 35 145 110 NA NA NA NA NA NA 13618 XM_029356707.2 230 313 251 112 352 NA NA NA NA NA NA 13619 XM_044319017.1 0 0 63 0 58 Q09328 5.3e-124 Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (EC 2.4.1.155) (Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase V) (GlcNAc-T V) (GNT-V) (Mannoside acetylglucosaminyltransferase 5) (N-acetylglucosaminyl-transferase V) [Cleaved into: Secreted alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (Secreted beta-1,6-N-acetylglucosaminyltransferase V) (Secreted GNT-V)] Homo sapiens (Human) negative regulation of protein tyrosine phosphatase activity [GO:1903614]; positive regulation of cell migration [GO:0030335]; positive regulation of receptor signaling pathway via STAT [GO:1904894]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279]; viral protein processing [GO:0019082] GO:0000139; GO:0004864; GO:0005794; GO:0006487; GO:0016020; GO:0018279; GO:0019082; GO:0030144; GO:0030145; GO:0030335; GO:0070062; GO:1903614; GO:1904894 13620 XR_003827340.2 274 147 94 66 37 Q9NS73 1.4e-42 MAP3K12-binding inhibitory protein 1 (MAPK upstream kinase-binding inhibitory protein) (MUK-binding inhibitory protein) Homo sapiens (Human) histone H3 acetylation [GO:0043966]; histone H3-K14 acetylation [GO:0044154]; positive regulation of gene expression [GO:0010628]; positive regulation of JNK cascade [GO:0046330]; regulation of cell cycle [GO:0051726]; regulation of cell division [GO:0051302]; regulation of DNA-templated transcription [GO:0006355]; regulation of embryonic development [GO:0045995]; regulation of histone deacetylation [GO:0031063]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tubulin deacetylation [GO:0090043] GO:0004860; GO:0005654; GO:0005730; GO:0005829; GO:0006355; GO:0006357; GO:0010628; GO:0031063; GO:0042802; GO:0043966; GO:0044154; GO:0045995; GO:0046330; GO:0051302; GO:0051726; GO:0072686; GO:0090043; GO:0140672 13621 XM_029332915.2 15 27 20 23 40 NA NA NA NA NA NA 13622 XM_044311055.1 43 59 15 29 15 P16157 1.09e-84 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 13623 XM_044311055.1 43 59 15 29 15 P16157 4.89e-76 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 13624 XM_044311055.1 43 59 15 29 15 P16157 6.38e-71 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 13625 XM_044311055.1 43 59 15 29 15 P16157 2.14e-68 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 13626 XM_044311055.1 43 59 15 29 15 P16157 7.65e-64 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 13627 XM_029342920.2 583 568 353 696 481 Q9Z2G9 4.09e-23 Oxidoreductase HTATIP2 (EC 1.1.1.-) Mus musculus (Mouse) angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; import into nucleus [GO:0051170]; positive regulation of programmed cell death [GO:0043068]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein autophosphorylation [GO:0046777]; regulation of angiogenesis [GO:0045765] GO:0001525; GO:0004674; GO:0005635; GO:0005737; GO:0005829; GO:0006915; GO:0016620; GO:0030154; GO:0043068; GO:0045765; GO:0045944; GO:0046777; GO:0051170; GO:0051287 13628 XM_044309974.1 479 387 381 375 584 Q15386 0 Ubiquitin-protein ligase E3C (EC 2.3.2.26) (HECT-type ubiquitin transferase E3C) (Homologous to E6AP carboxyl terminus homologous protein 2) (HectH2) (RTA-associated ubiquitin ligase) (RAUL) Homo sapiens (Human) protein K29-linked ubiquitination [GO:0035519]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000209; GO:0000502; GO:0006511; GO:0035519; GO:0061630; GO:0070936 13629 XR_006393276.1 518 2798 1126 1276 1721 NA NA NA NA NA NA 13630 XM_029334798.2 14 0 0 0 10 G3M4F8 9.66e-46 Octopamine receptor beta-2R (CsOA2B2) Chilo suppressalis (Asiatic rice borer moth) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cellular response to amine stimulus [GO:0071418]; octopamine signaling pathway [GO:0071927]; tyramine signaling pathway [GO:0071928] GO:0004989; GO:0005886; GO:0007189; GO:0008226; GO:0016020; GO:0071418; GO:0071927; GO:0071928 13631 XR_006393541.1 46 8 59 4 195 NA NA NA NA NA NA 13632 XM_044310303.1 1209 227 47 98 861 Q95SX7 4.66e-38 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 13633 XR_003824996.2 12 0 0 2 5 NA NA NA NA NA NA 13634 XM_029347166.2 142 146 80 74 388 NA NA NA NA NA NA 13635 XM_029343474.2 3 19 0 0 0 P05689 5.57e-132 Cathepsin Z (EC 3.4.18.1) Bos taurus (Bovine) proteolysis involved in protein catabolic process [GO:0051603] GO:0004197; GO:0005615; GO:0005764; GO:0051603 13636 XM_044324466.1 681 98 53 87 42 NA NA NA NA NA NA 13637 XM_029349892.2 3415 1794 1377 3357 1690 Q9HBR0 1.06e-93 Putative sodium-coupled neutral amino acid transporter 10 (Solute carrier family 38 member 10) Homo sapiens (Human) amino acid transmembrane transport [GO:0003333]; bone development [GO:0060348]; sodium ion transport [GO:0006814] GO:0003333; GO:0005794; GO:0006814; GO:0015179; GO:0016020; GO:0060348 13638 XM_029333146.2 897 930 474 699 387 Q5W8I8 1.72e-124 Vesicular glutamate transporter 2.1 (Protein blumenkohl) (Solute carrier family 17 member 6-B) (Vesicular glutamate transporter 2-A) Danio rerio (Zebrafish) (Brachydanio rerio) anion transport [GO:0006820]; chemical synaptic transmission [GO:0007268]; L-glutamate import [GO:0051938]; L-glutamate transmembrane transport [GO:0015813]; neurotransmitter loading into synaptic vesicle [GO:0098700]; phosphate ion homeostasis [GO:0055062]; phosphate ion transport [GO:0006817]; regulation of synapse structure or activity [GO:0050803]; response to stimulus [GO:0050896]; sodium-dependent phosphate transport [GO:0044341]; synaptic transmission, glutamatergic [GO:0035249]; visual perception [GO:0007601] GO:0005254; GO:0005313; GO:0005326; GO:0005436; GO:0005886; GO:0006817; GO:0006820; GO:0007268; GO:0007601; GO:0008021; GO:0015386; GO:0015813; GO:0016020; GO:0022857; GO:0030672; GO:0034707; GO:0035249; GO:0043005; GO:0044341; GO:0050803; GO:0050896; GO:0051938; GO:0055062; GO:0060076; GO:0098700; GO:0140788 13639 XM_029355570.2 2557 1793 1223 1214 1121 Q6IV57 2.6e-36 RING finger protein 141 Rattus norvegicus (Rat) protein autoubiquitination [GO:0051865]; regulation of DNA-templated transcription [GO:0006355] GO:0004842; GO:0006355; GO:0016020; GO:0046872; GO:0051865 13640 XM_029345624.2 22 0 18 47 58 NA NA NA NA NA NA 13641 XM_044319493.1 1 13 10 45 36 NA NA NA NA NA NA 13642 XM_029328586.2 0 13 0 0 0 P35348 3.38e-36 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) (Alpha-adrenergic receptor 1c) Homo sapiens (Human) activation of phospholipase C activity [GO:0007202]; adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; adult heart development [GO:0007512]; aging [GO:0007568]; apoptotic process [GO:0006915]; calcium ion transport into cytosol [GO:0060402]; cell growth involved in cardiac muscle cell development [GO:0061049]; cell-cell signaling [GO:0007267]; G protein-coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; micturition [GO:0060073]; multicellular organism aging [GO:0010259]; negative regulation of autophagy [GO:0010507]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure [GO:0001985]; negative regulation of Rho protein signal transduction [GO:0035024]; neuron-glial cell signaling [GO:0150099]; norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001994]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; pilomotor reflex [GO:0097195]; positive regulation of action potential [GO:0045760]; positive regulation of cardiac muscle contraction [GO:0060452]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; positive regulation of systemic arterial blood pressure [GO:0003084]; positive regulation of the force of heart contraction by epinephrine-norepinephrine [GO:0001997]; positive regulation of vasoconstriction [GO:0045907]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; response to hormone [GO:0009725]; response to xenobiotic stimulus [GO:0009410]; signal transduction [GO:0007165]; smooth muscle contraction [GO:0006939] GO:0000165; GO:0001985; GO:0001994; GO:0001996; GO:0001997; GO:0003084; GO:0004930; GO:0004937; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0005901; GO:0006915; GO:0006939; GO:0007165; GO:0007186; GO:0007200; GO:0007202; GO:0007204; GO:0007267; GO:0007512; GO:0007568; GO:0008285; GO:0009410; GO:0009725; GO:0010259; GO:0010507; GO:0010613; GO:0030018; GO:0030315; GO:0031965; GO:0032230; GO:0035024; GO:0035556; GO:0042734; GO:0043231; GO:0043410; GO:0045211; GO:0045760; GO:0045907; GO:0045987; GO:0046982; GO:0060073; GO:0060402; GO:0060452; GO:0061049; GO:0070374; GO:0071880; GO:0090037; GO:0097195; GO:0098691; GO:0098978; GO:0098982; GO:0099171; GO:0150099; GO:1903997 13643 XR_006396739.1 44 0 0 0 33 NA NA NA NA NA NA 13644 XM_044310885.1 36 15 51 67 128 Q96PB1 3.18e-123 N-acetylneuraminate 9-O-acetyltransferase (EC 2.3.1.45) (CAS1 domain-containing protein 1) (Sialate O-acetyltransferase) (SOAT) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975] GO:0000139; GO:0005975; GO:0047186 13645 XM_029327431.2 34355 25911 10421 17342 15701 Q3ZCF5 0 Ornithine aminotransferase, mitochondrial (EC 2.6.1.13) (Ornithine--oxo-acid aminotransferase) Bos taurus (Bovine) L-proline biosynthetic process [GO:0055129] GO:0004587; GO:0005759; GO:0030170; GO:0042802; GO:0050155; GO:0055129 13646 XM_044318424.1 33 224 97 50 72 NA NA NA NA NA NA 13647 XM_029328229.2 124 117 117 113 358 E7FAM5 5.4e-32 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 13648 XM_044318718.1 334 519 431 493 394 NA NA NA NA NA NA 13649 XM_044322123.1 265 589 177 262 320 Q6NRS1 5.25e-121 Inhibitor of Bruton tyrosine kinase (IBtk) Xenopus laevis (African clawed frog) NA GO:0005737; GO:0016020 13650 XM_044322123.1 265 589 177 262 320 Q6NRS1 1.42e-75 Inhibitor of Bruton tyrosine kinase (IBtk) Xenopus laevis (African clawed frog) NA GO:0005737; GO:0016020 13651 XM_029358688.2 3111 3259 1975 3420 3494 P83038 0 Histone deacetylase 4 (HD4) (EC 3.5.1.98) Gallus gallus (Chicken) B cell activation [GO:0042113]; B cell differentiation [GO:0030183]; chromatin organization [GO:0006325]; histone deacetylation [GO:0016575]; histone H4 deacetylation [GO:0070933]; inflammatory response [GO:0006954]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of striated muscle tissue development [GO:0045843]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399] GO:0000118; GO:0000122; GO:0004407; GO:0005737; GO:0006325; GO:0006954; GO:0007399; GO:0016575; GO:0030183; GO:0042113; GO:0045843; GO:0045892; GO:0046872; GO:0070933; GO:0140297 13652 XM_044325960.1 25 6 46 22 41 NA NA NA NA NA NA 13653 XM_029341645.2 239 262 167 241 361 Q9H7Z3 2.32e-159 Nuclear exosome regulator NRDE2 (Protein NRDE2 homolog) Homo sapiens (Human) cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; mitotic cell cycle [GO:0000278]; mRNA processing [GO:0006397]; negative regulation of RNA catabolic process [GO:1902369]; positive regulation of RNA export from nucleus [GO:0046833]; RNA splicing [GO:0008380]; RNA-mediated post-transcriptional gene silencing [GO:0035194] GO:0000278; GO:0005634; GO:0005654; GO:0005730; GO:0006397; GO:0006974; GO:0008380; GO:0016607; GO:0035194; GO:0046833; GO:0051301; GO:1902369 13654 XM_044313068.1 110 84 12 39 38 Q80XJ3 2.37e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 13655 XM_029343005.2 206 310 253 463 334 O88874 2.24e-98 Cyclin-K Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; in utero embryonic development [GO:0001701]; negative regulation by host of viral genome replication [GO:0044828]; negative regulation of stem cell differentiation [GO:2000737]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues [GO:2001165]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; regulation of signal transduction [GO:0009966]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366] GO:0001701; GO:0002944; GO:0002945; GO:0004693; GO:0005634; GO:0005654; GO:0006357; GO:0006366; GO:0006974; GO:0007049; GO:0008024; GO:0008353; GO:0009966; GO:0016538; GO:0019901; GO:0032786; GO:0032968; GO:0044828; GO:0051301; GO:0061575; GO:0070816; GO:2000737; GO:2001165 13656 XM_029350735.2 2520 4227 4298 4972 6730 NA NA NA NA NA NA 13657 XM_029330383.2 684 391 381 446 389 Q86BN8 2.23e-59 Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 (EC 3.1.3.27) (PTEN-like phosphatase) (PTEN-like protein) (Protein-tyrosine phosphatase mitochondrial 1-like protein) (EC 3.1.3.16, EC 3.1.3.48) Drosophila melanogaster (Fruit fly) dephosphorylation [GO:0016311]; liquid clearance, open tracheal system [GO:0035002]; phosphatidylglycerol biosynthetic process [GO:0006655]; protein dephosphorylation [GO:0006470] GO:0004439; GO:0004725; GO:0005739; GO:0005743; GO:0006470; GO:0006655; GO:0008138; GO:0008962; GO:0016311; GO:0017018; GO:0035002 13658 XM_044311385.1 128 94 47 123 15 Q9H5F2 6.36e-26 Uncharacterized protein CFAP68 (cilia and flagella associated protein 68) Homo sapiens (Human) NA GO:0005654 13659 XM_044317303.1 276 183 90 176 194 NA NA NA NA NA NA 13660 XM_044316139.1 11 16 35 50 48 Q87PP5 1.12e-93 Glycine betaine/proline/choline/ectoine transporter VP1456 Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) amino acid transport [GO:0006865] GO:0005886; GO:0006865; GO:0022857 13661 XM_029340358.2 1777 1183 910 2157 2074 Q6P9Q6 1.12e-87 FK506-binding protein 15 (FKBP-15) (133 kDa FK506-binding protein) (133 kDa FKBP) (FKBP-133) (WASP and FKBP-like) (WAFL) Mus musculus (Mouse) endocytosis [GO:0006897] GO:0003779; GO:0005768; GO:0005769; GO:0006897; GO:0015629; GO:0016020; GO:0030424; GO:0030426 13662 XM_029340358.2 1777 1183 910 2157 2074 Q6P9Q6 1.09e-46 FK506-binding protein 15 (FKBP-15) (133 kDa FK506-binding protein) (133 kDa FKBP) (FKBP-133) (WASP and FKBP-like) (WAFL) Mus musculus (Mouse) endocytosis [GO:0006897] GO:0003779; GO:0005768; GO:0005769; GO:0006897; GO:0015629; GO:0016020; GO:0030424; GO:0030426 13663 XM_029347195.2 16 30 64 27 40 Q8NB46 5.58e-24 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (PP6-ARS-C) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C) (Ankyrin repeat domain-containing protein 52) Homo sapiens (Human) NA NA 13664 XM_029352918.2 261 285 174 285 207 Q4V8D7 1.29e-130 Protein FAM221A Rattus norvegicus (Rat) NA NA 13665 XM_029344425.2 960 765 196 614 970 Q8VCH8 1.37e-75 UBX domain-containing protein 4 (Erasin) (UBX domain-containing protein 2) Mus musculus (Mouse) response to unfolded protein [GO:0006986]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0005635; GO:0005783; GO:0005789; GO:0005829; GO:0006986; GO:0030433 13666 XM_029356452.2 0 2 28 2 61 NA NA NA NA NA NA 13667 XR_006393683.1 44 0 0 11 6 NA NA NA NA NA NA 13668 XM_029346898.2 65 0 0 35 227 A8KBE0 6.7e-72 Oxidation resistance protein 1 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005739 13669 XM_029348248.2 1370 1507 794 1245 990 Q5XJ36 1e-54 Parkinson disease protein 7 homolog (Maillard deglycase) (Parkinsonism-associated deglycase) (Protein DJ-1zDJ-1) (zDJ-1) (Protein/nucleic acid deglycase DJ-1) (EC 3.1.2.-, EC 3.5.1.-, EC 3.5.1.124) Danio rerio (Zebrafish) (Brachydanio rerio) autophagy [GO:0006914]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to oxidative stress [GO:0034599]; DNA repair [GO:0006281]; glucose homeostasis [GO:0042593]; glycolate biosynthetic process [GO:0046295]; glyoxal metabolic process [GO:1903189]; guanine deglycation [GO:0106044]; guanine deglycation, glyoxal removal [GO:0106046]; guanine deglycation, methylglyoxal removal [GO:0106045]; inflammatory response [GO:0006954]; insulin secretion [GO:0030073]; negative regulation of cell death [GO:0060548]; negative regulation of neuron death [GO:1901215]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; positive regulation of oxidative phosphorylation uncoupler activity [GO:2000277]; protein deglycosylation [GO:0006517]; protein stabilization [GO:0050821]; proteolysis [GO:0006508]; regulation of neuron apoptotic process [GO:0043523]; response to oxidative stress [GO:0006979]; single fertilization [GO:0007338] GO:0003729; GO:0005634; GO:0005737; GO:0005739; GO:0005783; GO:0005886; GO:0006281; GO:0006508; GO:0006517; GO:0006914; GO:0006954; GO:0006979; GO:0007338; GO:0008233; GO:0016684; GO:0030073; GO:0034599; GO:0042593; GO:0042803; GO:0043523; GO:0045121; GO:0046295; GO:0050821; GO:0060548; GO:0070301; GO:0106044; GO:0106045; GO:0106046; GO:1901215; GO:1903189; GO:1903427; GO:1990422; GO:2000277 13670 XR_006391659.1 29 14 10 0 0 NA NA NA NA NA NA 13671 XM_029332310.2 531 344 348 562 705 P68827 4.18e-121 N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase (EC 3.1.4.45) (Mannose 6-phosphate-uncovering enzyme) (Phosphodiester alpha-GlcNAcase) Bos taurus (Bovine) protein glycosylation [GO:0006486]; secretion of lysosomal enzymes [GO:0033299] GO:0003944; GO:0006486; GO:0032580; GO:0033299 13672 XR_006395937.1 78 96 41 121 131 NA NA NA NA NA NA 13673 XM_029343440.2 2063 1355 887 2244 1746 Q99NH0 0 Ankyrin repeat domain-containing protein 17 (Ankyrin repeat domain-containing protein FOE) (Gene trap ankyrin repeat protein) Mus musculus (Mouse) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; endoderm development [GO:0007492]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0007492; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 13674 XM_029343440.2 2063 1355 887 2244 1746 Q99NH0 0 Ankyrin repeat domain-containing protein 17 (Ankyrin repeat domain-containing protein FOE) (Gene trap ankyrin repeat protein) Mus musculus (Mouse) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; endoderm development [GO:0007492]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0007492; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 13675 XM_029343440.2 2063 1355 887 2244 1746 Q99NH0 1.42e-51 Ankyrin repeat domain-containing protein 17 (Ankyrin repeat domain-containing protein FOE) (Gene trap ankyrin repeat protein) Mus musculus (Mouse) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; endoderm development [GO:0007492]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0007492; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 13676 XM_029343440.2 2063 1355 887 2244 1746 Q99NH0 3.01e-51 Ankyrin repeat domain-containing protein 17 (Ankyrin repeat domain-containing protein FOE) (Gene trap ankyrin repeat protein) Mus musculus (Mouse) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; endoderm development [GO:0007492]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0007492; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 13677 XM_029343440.2 2063 1355 887 2244 1746 Q99NH0 1.05e-49 Ankyrin repeat domain-containing protein 17 (Ankyrin repeat domain-containing protein FOE) (Gene trap ankyrin repeat protein) Mus musculus (Mouse) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; endoderm development [GO:0007492]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0007492; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 13678 XM_029343440.2 2063 1355 887 2244 1746 Q99NH0 3.47e-43 Ankyrin repeat domain-containing protein 17 (Ankyrin repeat domain-containing protein FOE) (Gene trap ankyrin repeat protein) Mus musculus (Mouse) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; endoderm development [GO:0007492]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0007492; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 13679 XM_029343440.2 2063 1355 887 2244 1746 Q99NH0 5.47e-43 Ankyrin repeat domain-containing protein 17 (Ankyrin repeat domain-containing protein FOE) (Gene trap ankyrin repeat protein) Mus musculus (Mouse) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; endoderm development [GO:0007492]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0007492; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 13680 XM_029343440.2 2063 1355 887 2244 1746 Q99NH0 1.07e-42 Ankyrin repeat domain-containing protein 17 (Ankyrin repeat domain-containing protein FOE) (Gene trap ankyrin repeat protein) Mus musculus (Mouse) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; endoderm development [GO:0007492]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0007492; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 13681 XM_029343440.2 2063 1355 887 2244 1746 Q99NH0 9.89e-40 Ankyrin repeat domain-containing protein 17 (Ankyrin repeat domain-containing protein FOE) (Gene trap ankyrin repeat protein) Mus musculus (Mouse) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; endoderm development [GO:0007492]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0007492; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 13682 XM_029343440.2 2063 1355 887 2244 1746 Q99NH0 1.96e-38 Ankyrin repeat domain-containing protein 17 (Ankyrin repeat domain-containing protein FOE) (Gene trap ankyrin repeat protein) Mus musculus (Mouse) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; endoderm development [GO:0007492]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0007492; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 13683 XM_029343440.2 2063 1355 887 2244 1746 Q99NH0 4.61e-34 Ankyrin repeat domain-containing protein 17 (Ankyrin repeat domain-containing protein FOE) (Gene trap ankyrin repeat protein) Mus musculus (Mouse) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; endoderm development [GO:0007492]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0007492; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 13684 XM_029343440.2 2063 1355 887 2244 1746 Q99NH0 7.2e-34 Ankyrin repeat domain-containing protein 17 (Ankyrin repeat domain-containing protein FOE) (Gene trap ankyrin repeat protein) Mus musculus (Mouse) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; endoderm development [GO:0007492]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0007492; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 13685 XM_029343440.2 2063 1355 887 2244 1746 Q99NH0 2.16e-31 Ankyrin repeat domain-containing protein 17 (Ankyrin repeat domain-containing protein FOE) (Gene trap ankyrin repeat protein) Mus musculus (Mouse) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; endoderm development [GO:0007492]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0007492; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 13686 XM_029343440.2 2063 1355 887 2244 1746 Q99NH0 1.8e-23 Ankyrin repeat domain-containing protein 17 (Ankyrin repeat domain-containing protein FOE) (Gene trap ankyrin repeat protein) Mus musculus (Mouse) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; endoderm development [GO:0007492]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0007492; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 13687 XM_044306907.1 72 0 21 83 0 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 13688 XM_044306907.1 72 0 21 83 0 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 13689 XM_044306907.1 72 0 21 83 0 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 13690 XM_044306907.1 72 0 21 83 0 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 13691 XM_044306907.1 72 0 21 83 0 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 13692 XM_044306907.1 72 0 21 83 0 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 13693 XM_044306907.1 72 0 21 83 0 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 13694 XM_044306907.1 72 0 21 83 0 P07207 2.47e-173 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 13695 XM_044306907.1 72 0 21 83 0 P07207 2.28e-136 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 13696 XM_029337888.2 9782 5559 3392 3971 1707 NA NA NA NA NA NA 13697 XM_044313090.1 0 0 66 137 0 NA NA NA NA NA NA 13698 XM_044310948.1 29 14 36 90 12 NA NA NA NA NA NA 13699 XM_044309746.1 5 0 19 1 29 NA NA NA NA NA NA 13700 XR_003825565.2 7481 9515 2838 7811 4931 NA NA NA NA NA NA 13701 XM_029351381.2 11 52 31 91 58 NA NA NA NA NA NA 13702 XM_044317697.1 0 0 2 27 14 Q5F2F2 3.61e-30 Protein ABHD15 (Alpha/beta hydrolase domain-containing protein 15) (Abhydrolase domain-containing protein 15) Mus musculus (Mouse) cellular lipid metabolic process [GO:0044255] GO:0005576; GO:0034338; GO:0044255; GO:0047372 13703 XM_044319471.1 1 48 26 164 174 Q7TNH6 3.38e-39 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 13704 XM_044319471.1 1 48 26 164 174 Q7TNH6 1.03e-36 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 13705 XM_044319471.1 1 48 26 164 174 Q7TNH6 3.88e-32 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 13706 XM_044319471.1 1 48 26 164 174 Q7TNH6 1.01e-31 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 13707 XM_044319471.1 1 48 26 164 174 Q7TNH6 2.2e-31 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 13708 XM_044319471.1 1 48 26 164 174 Q7TNH6 9.46e-21 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 13709 XM_044314662.1 1 0 6 5 0 NA NA NA NA NA NA 13710 XM_044313532.1 1869 910 768 1380 1491 NA NA NA NA NA NA 13711 XM_029350962.2 165 93 67 140 123 NA NA NA NA NA NA 13712 XR_003824255.2 4644 2892 3729 6019 4952 NA NA NA NA NA NA 13713 XM_044327849.1 668 636 92 301 435 NA NA NA NA NA NA 13714 XR_006393988.1 152 67 68 112 35 NA NA NA NA NA NA 13715 XM_029345356.2 50 75 59 64 175 E7FAM5 6.61e-39 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 13716 XM_029342651.2 1825 1276 854 1732 1101 Q8BKF1 0 DNA-directed RNA polymerase, mitochondrial (MtRPOL) (EC 2.7.7.6) Mus musculus (Mouse) mitochondrial transcription [GO:0006390]; transcription initiation at mitochondrial promoter [GO:0006391] GO:0000175; GO:0001018; GO:0003896; GO:0003899; GO:0005739; GO:0005759; GO:0006390; GO:0006391; GO:0032991; GO:0034245; GO:0042645; GO:0043565 13717 XM_029347083.2 410 229 220 220 173 Q6P6X9 7.5e-70 Nucleoporin NUP35 (35 kDa nucleoporin) (Nuclear pore complex protein Nup53) (Nucleoporin NUP53) Danio rerio (Zebrafish) (Brachydanio rerio) mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; nuclear pore organization [GO:0006999] GO:0003676; GO:0005543; GO:0006607; GO:0006999; GO:0017056; GO:0031965; GO:0044613; GO:0044615; GO:0051028 13718 XM_044324226.1 29 17 170 28 522 Q9VBW3 6.37e-82 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 13719 XM_044307089.1 10 3 8 5 22 Q9C907 3.73e-69 Glycerophosphodiester phosphodiesterase GDPD5 (EC 3.1.4.46) (Glycerophosphodiester phosphodiesterase 5) (ATGDPD5) Arabidopsis thaliana (Mouse-ear cress) glycerol metabolic process [GO:0006071]; lipid metabolic process [GO:0006629] GO:0000325; GO:0005576; GO:0005829; GO:0006071; GO:0006629; GO:0008889 13720 XR_003824537.2 1083 1169 308 557 307 NA NA NA NA NA NA 13721 XM_044327303.1 0 0 0 7 0 NA NA NA NA NA NA 13722 XR_006396243.1 5 4 28 24 28 NA NA NA NA NA NA 13723 XM_044313027.1 1 1 2 11 24 Q8T0Q4 1.68e-22 NA NA NA NA 13724 XR_003825041.2 369 836 702 428 450 NA NA NA NA NA NA 13725 XM_029328452.2 452 584 597 1137 0 Q63665 2.77e-60 Upstream stimulatory factor 2 (Major late transcription factor 2) (Upstream transcription factor 2) Rattus norvegicus (Rat) lactation [GO:0007595]; lipid homeostasis [GO:0055088]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter by glucose [GO:0000432]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000432; GO:0000978; GO:0000981; GO:0003677; GO:0003690; GO:0003700; GO:0005634; GO:0006357; GO:0007595; GO:0042802; GO:0042803; GO:0043425; GO:0043565; GO:0044877; GO:0045893; GO:0045944; GO:0046982; GO:0055088; GO:1990837 13726 XR_006396545.1 3 0 12 8 47 NA NA NA NA NA NA 13727 XM_044313652.1 71 34 89 25 0 Q924C1 3.8e-58 Exportin-5 (Exp5) (Ran-binding protein 21) Mus musculus (Mouse) positive regulation of post-transcriptional gene silencing by RNA [GO:1900370]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; RNA export from nucleus [GO:0006405] GO:0000049; GO:0003723; GO:0003729; GO:0005049; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006405; GO:0006611; GO:0016442; GO:0031267; GO:0035281; GO:0042565; GO:0070883; GO:1900370; GO:1905172 13728 XR_006398049.1 0 0 0 2 14 NA NA NA NA NA NA 13729 XM_029334869.2 0 0 0 22 7 NA NA NA NA NA NA 13730 XM_029339604.2 675 647 1307 608 406 NA NA NA NA NA NA 13731 XR_006394882.1 29 0 0 0 0 NA NA NA NA NA NA 13732 XM_044325894.1 34 25 17 22 47 P48058 7.58e-93 Glutamate receptor 4 (GluR-4) (GluR4) (AMPA-selective glutamate receptor 4) (GluR-D) (Glutamate receptor ionotropic, AMPA 4) (GluA4) Homo sapiens (Human) glutamate receptor signaling pathway [GO:0007215]; negative regulation of smooth muscle cell apoptotic process [GO:0034392] GO:0001540; GO:0004970; GO:0004971; GO:0005886; GO:0007215; GO:0015276; GO:0030666; GO:0032281; GO:0034392; GO:0038023; GO:0043025; GO:0043197; GO:0045211; GO:0099507; GO:1903561 13733 XM_029357105.2 564 367 232 246 314 A0A2B4RNI3 2.93e-30 NA NA NA NA 13734 XM_044308376.1 0 0 0 209 0 Q9UJX3 2.65e-121 Anaphase-promoting complex subunit 7 (APC7) (Cyclosome subunit 7) Homo sapiens (Human) anaphase-promoting complex-dependent catabolic process [GO:0031145]; brain development [GO:0007420]; cell division [GO:0051301]; metaphase/anaphase transition of mitotic cell cycle [GO:0007091]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; protein K11-linked ubiquitination [GO:0070979]; protein ubiquitination [GO:0016567]; regulation of meiotic cell cycle [GO:0051445]; regulation of mitotic cell cycle [GO:0007346] GO:0000792; GO:0005634; GO:0005654; GO:0005680; GO:0005737; GO:0005819; GO:0005829; GO:0007091; GO:0007346; GO:0007420; GO:0015630; GO:0016567; GO:0019903; GO:0031145; GO:0045842; GO:0051301; GO:0051445; GO:0070979; GO:0140767 13735 XM_029328668.2 0 0 64 52 12 NA NA NA NA NA NA 13736 XM_029354639.2 287 154 115 190 308 NA NA NA NA NA NA 13737 XM_044316868.1 39 11 86 16 83 Q96A58 3.27e-35 Ras-related and estrogen-regulated growth inhibitor (EC 3.6.5.2) Homo sapiens (Human) negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; Ras protein signal transduction [GO:0007265]; response to hormone [GO:0009725]; small GTPase mediated signal transduction [GO:0007264] GO:0001650; GO:0003924; GO:0003925; GO:0005525; GO:0005634; GO:0005654; GO:0005829; GO:0005886; GO:0007264; GO:0007265; GO:0008285; GO:0009725; GO:0019003; GO:0030308; GO:0030331 13738 XM_029332923.2 730 439 392 660 497 Q8JHJ2 0 ATP-dependent RNA helicase DDX55 (EC 3.6.4.13) (DEAD box protein 55) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0003723; GO:0003724; GO:0005524; GO:0005730; GO:0016887 13739 XM_044327145.1 397 50 370 81 493 NA NA NA NA NA NA 13740 XM_044310199.1 139 67 183 179 948 NA NA NA NA NA NA 13741 XM_044317338.1 40 23 42 19 43 Q95SX7 9.6e-24 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 13742 XM_044312879.1 7 4 10 29 0 NA NA NA NA NA NA 13743 XM_029328873.2 0 65 0 41 0 Q28DB0 1.42e-159 Tetratricopeptide repeat protein 39B (TPR repeat protein 39B) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) lipid metabolic process [GO:0006629] GO:0006629 13744 XM_044317413.1 77 12 32 64 340 NA NA NA NA NA NA 13745 XR_006398115.1 0 6 2 0 15 NA NA NA NA NA NA 13746 XM_044322670.1 8 5 0 11 3 NA NA NA NA NA NA 13747 XM_044309740.1 17 2 7 1 38 NA NA NA NA NA NA 13748 XM_044310124.1 0 0 0 229 87 NA NA NA NA NA NA 13749 XM_044318039.1 0 8 92 4 4 NA NA NA NA NA NA 13750 XM_044314499.1 0 0 0 0 20 P35067 3.99e-85 Histone H2B Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 13751 XM_029354738.2 0 0 76 0 64 P0CT39 5.02e-79 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 13752 XR_003825051.2 30 0 65 41 101 NA NA NA NA NA NA 13753 XM_044312837.1 143 113 77 168 164 P54644 5.22e-66 RAC family serine/threonine-protein kinase homolog (EC 2.7.11.1) Dictyostelium discoideum (Social amoeba) bleb assembly [GO:0032060]; chemotaxis to cAMP [GO:0043327]; culmination involved in sorocarp development [GO:0031154]; establishment of cell polarity [GO:0030010]; establishment or maintenance of cell polarity [GO:0007163]; intracellular signal transduction [GO:0035556]; macropinocytosis [GO:0044351]; maintenance of cell polarity [GO:0030011]; mitotic cytokinesis [GO:0000281]; myosin II filament assembly [GO:0031036]; negative regulation of phagocytosis [GO:0050765]; negative regulation of Ras protein signal transduction [GO:0046580]; peptidyl-serine phosphorylation [GO:0018105]; phagosome maturation [GO:0090382]; phosphatidylinositol-mediated signaling [GO:0048015]; polyphosphate-mediated signaling [GO:0110094]; positive regulation of chemorepellent activity [GO:1903669]; positive regulation of macropinocytosis [GO:1905303]; protein phosphorylation [GO:0006468]; pseudopodium assembly [GO:0031269]; regulation of cell migration [GO:0030334]; regulation of chemotaxis [GO:0050920]; response to differentiation-inducing factor 1 [GO:1903013]; response to hydrogen peroxide [GO:0042542] GO:0000281; GO:0004674; GO:0004691; GO:0005524; GO:0005547; GO:0005829; GO:0005886; GO:0005938; GO:0006468; GO:0007163; GO:0018105; GO:0019887; GO:0030010; GO:0030011; GO:0030295; GO:0030334; GO:0031036; GO:0031154; GO:0031252; GO:0031269; GO:0032060; GO:0035556; GO:0042542; GO:0043327; GO:0044351; GO:0046580; GO:0048015; GO:0050765; GO:0050920; GO:0090382; GO:0106310; GO:0110094; GO:1903013; GO:1903669; GO:1905303 13754 XM_029339627.2 379 104 109 177 180 Q8VCK5 5.93e-134 Kelch-like protein 20 (Kelch-like ECT2-interacting protein) Mus musculus (Mouse) Golgi to endosome transport [GO:0006895]; negative regulation of apoptotic process [GO:0043066]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K33-linked ubiquitination [GO:1990390]; protein transport [GO:0015031]; protein ubiquitination [GO:0016567] GO:0003779; GO:0004842; GO:0005737; GO:0005794; GO:0005802; GO:0005829; GO:0006895; GO:0015031; GO:0016567; GO:0016605; GO:0019964; GO:0030424; GO:0030425; GO:0031463; GO:0043066; GO:0043161; GO:0048471; GO:1990390 13755 XM_029341555.2 224 93 70 224 256 NA NA NA NA NA NA 13756 XM_029351494.2 0 0 0 16 22 NA NA NA NA NA NA 13757 XM_029334474.2 0 71 0 189 0 NA NA NA NA NA NA 13758 XR_006396199.1 0 18 2 104 126 NA NA NA NA NA NA 13759 XM_044310204.1 0 0 9 2 0 NA NA NA NA NA NA 13760 XM_044315160.1 0 0 0 123 0 P20664 1.4e-159 DNA primase small subunit (EC 2.7.7.102) (DNA primase 49 kDa subunit) (p49) Mus musculus (Mouse) DNA replication initiation [GO:0006270]; DNA replication, synthesis of RNA primer [GO:0006269] GO:0000287; GO:0003896; GO:0005658; GO:0006269; GO:0006270; GO:0008270; GO:0032553 13761 XM_044319298.1 91 0 26 0 0 Q8R4K8 0 Pappalysin-1 (EC 3.4.24.79) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase) (Pregnancy-associated plasma protein A) (PAPP-A) Mus musculus (Mouse) cell surface receptor signaling pathway [GO:0007166]; female pregnancy [GO:0007565]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to dexamethasone [GO:0071548]; response to follicle-stimulating hormone [GO:0032354] GO:0004175; GO:0004222; GO:0005576; GO:0005615; GO:0006508; GO:0007166; GO:0007565; GO:0008237; GO:0030163; GO:0032354; GO:0046872; GO:0071548 13762 XM_029351954.2 1437 1112 617 1280 1059 Q2M2T6 8.17e-34 PAT complex subunit Asterix (Protein WDR83OS homolog) (Protein associated with the ER translocon of 10kDa) (PAT-10) (PAT10) Bos taurus (Bovine) protein insertion into ER membrane [GO:0045048] GO:0005789; GO:0044183; GO:0045048 13763 XM_044320899.1 1388 1844 1086 4746 6486 Q9K7A0 1.88e-29 Probable cysteine desulfurase (EC 2.8.1.7) Halalkalibacterium halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) (Bacillus halodurans) cysteine metabolic process [GO:0006534] GO:0006534; GO:0030170; GO:0031071 13764 XM_044307010.1 26 6 2 5 11 Q8K3Z0 2.03e-29 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 13765 XM_044325601.1 0 3 0 6 0 NA NA NA NA NA NA 13766 XM_044310967.1 24 5 47 9 107 NA NA NA NA NA NA 13767 XM_044308541.1 37 13 0 121 0 NA NA NA NA NA NA 13768 XM_029356964.2 1225 0 0 0 0 Q6NZW8 7.37e-118 ADP-ribosylation factor-like protein 8B-A Danio rerio (Zebrafish) (Brachydanio rerio) anterograde axonal transport [GO:0008089]; autophagosome-lysosome fusion [GO:0061909]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; late endosome to lysosome transport [GO:1902774]; lysosome localization [GO:0032418]; protein transport [GO:0015031] GO:0003924; GO:0005525; GO:0005764; GO:0005765; GO:0005819; GO:0007059; GO:0008089; GO:0015031; GO:0031902; GO:0032418; GO:0051301; GO:0061909; GO:1902774; GO:1904115 13769 XM_044308823.1 7 0 0 0 0 NA NA NA NA NA NA 13770 XM_029333062.2 154 227 181 178 230 Q6UXP7 2.16e-60 Protein FAM151B Homo sapiens (Human) NA GO:0005615 13771 XM_044324501.1 9 0 1 0 0 NA NA NA NA NA NA 13772 XM_044309352.1 12 20 20 2 0 NA NA NA NA NA NA 13773 XM_029356932.2 727 345 327 509 472 Q5R8V9 1.81e-35 Zinc finger C3HC-type protein 1 (Nuclear-interacting partner of ALK) (Nuclear-interacting partner of anaplastic lymphoma kinase) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cell cycle [GO:0007049]; cell division [GO:0051301]; protein ubiquitination [GO:0016567] GO:0005634; GO:0007049; GO:0008270; GO:0016567; GO:0051301 13774 XM_044322323.1 88 79 26 117 41 NA NA NA NA NA NA 13775 XM_044311872.1 0 0 0 0 32 NA NA NA NA NA NA 13776 XR_006392177.1 8 2 2 22 8 NA NA NA NA NA NA 13777 XM_044324045.1 15 0 0 131 53 D3ZZL9 5.72e-90 GRIP and coiled-coil domain-containing protein 2 (185 kDa Golgi coiled-coil protein) Rattus norvegicus (Rat) Golgi ribbon formation [GO:0090161]; late endosome to Golgi transport [GO:0034499]; microtubule anchoring [GO:0034453]; microtubule organizing center organization [GO:0031023]; protein localization to Golgi apparatus [GO:0034067]; protein targeting to lysosome [GO:0006622]; recycling endosome to Golgi transport [GO:0071955]; regulation of protein exit from endoplasmic reticulum [GO:0070861]; retrograde transport, endosome to Golgi [GO:0042147] GO:0005794; GO:0005802; GO:0005829; GO:0006622; GO:0016020; GO:0031023; GO:0034067; GO:0034453; GO:0034499; GO:0042147; GO:0042802; GO:0070861; GO:0071955; GO:0090161 13778 XM_029336257.2 161 10 32 67 149 NA NA NA NA NA NA 13779 XM_044329180.1 0 0 0 0 40 NA NA NA NA NA NA 13780 XR_006393842.1 567 77 666 191 2950 NA NA NA NA NA NA 13781 XR_006393546.1 85 0 0 0 6 NA NA NA NA NA NA 13782 XM_044311722.1 48 95 55 32 59 NA NA NA NA NA NA 13783 XM_029334027.2 74 124 158 51 158 Q54CI5 2.19e-25 DPH4 homolog (DnaJ homolog subfamily C member 24) Dictyostelium discoideum (Social amoeba) peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]; tRNA wobble uridine modification [GO:0002098] GO:0001671; GO:0002098; GO:0005634; GO:0005829; GO:0017183; GO:0046872 13784 XM_029343605.2 51 45 30 64 97 NA NA NA NA NA NA 13785 XM_029349619.2 7 0 15 65 4 Q09575 4.84e-29 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 13786 XM_029342605.2 111 46 47 142 32 Q9VBW3 3.64e-85 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 13787 XM_044324764.1 0 23 0 66 5 Q96RW7 3.82e-52 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 13788 XM_044324764.1 0 23 0 66 5 Q96RW7 1.85e-43 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 13789 XM_044324764.1 0 23 0 66 5 Q96RW7 1.08e-42 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 13790 XM_044324764.1 0 23 0 66 5 Q96RW7 1.86e-39 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 13791 XM_044324764.1 0 23 0 66 5 Q96RW7 2.16e-37 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 13792 XM_044324764.1 0 23 0 66 5 Q96RW7 6.86e-36 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 13793 XM_044324764.1 0 23 0 66 5 Q96RW7 3.11e-35 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 13794 XM_044324764.1 0 23 0 66 5 Q96RW7 1.64e-32 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 13795 XM_044324764.1 0 23 0 66 5 Q96RW7 7.6e-32 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 13796 XM_044324764.1 0 23 0 66 5 Q96RW7 4.13e-26 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 13797 XM_044324764.1 0 23 0 66 5 Q96RW7 4.2e-26 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 13798 XM_044310149.1 61 2 8 14 272 NA NA NA NA NA NA 13799 XM_044324436.1 115 88 25 96 161 NA NA NA NA NA NA 13800 XM_029335285.2 62 49 47 155 210 Q92051 6.51e-53 Carbonic anhydrase (EC 4.2.1.1) (Carbonate dehydratase) Danio rerio (Zebrafish) (Brachydanio rerio) carbon dioxide transport [GO:0015670]; hypotonic salinity response [GO:0042539]; one-carbon metabolic process [GO:0006730] GO:0004089; GO:0005737; GO:0006730; GO:0008270; GO:0015670; GO:0016836; GO:0042539 13801 XM_044327167.1 647 224 249 454 82 NA NA NA NA NA NA 13802 XM_029340958.2 1931 1110 798 1759 1494 Q6Y7W6 1.48e-24 GRB10-interacting GYF protein 2 (PERQ amino acid-rich with GYF domain-containing protein 2) (Trinucleotide repeat-containing gene 15 protein) Homo sapiens (Human) adult locomotory behavior [GO:0008344]; feeding behavior [GO:0007631]; homeostasis of number of cells within a tissue [GO:0048873]; insulin-like growth factor receptor signaling pathway [GO:0048009]; mitotic G1 DNA damage checkpoint signaling [GO:0031571]; mRNA destabilization [GO:0061157]; multicellular organism growth [GO:0035264]; musculoskeletal movement [GO:0050881]; negative regulation of translation [GO:0017148]; neuromuscular process controlling balance [GO:0050885]; post-embryonic development [GO:0009791]; post-transcriptional gene silencing [GO:0016441]; protein metabolic process [GO:0019538]; spinal cord motor neuron differentiation [GO:0021522] GO:0003723; GO:0005768; GO:0005783; GO:0005794; GO:0005829; GO:0007631; GO:0008344; GO:0009791; GO:0010494; GO:0016020; GO:0016441; GO:0017148; GO:0019538; GO:0021522; GO:0031571; GO:0031982; GO:0032991; GO:0035264; GO:0043204; GO:0045296; GO:0048009; GO:0048873; GO:0050881; GO:0050885; GO:0061157; GO:0070064; GO:1990635 13803 XM_029340958.2 1931 1110 798 1759 1494 Q6Y7W6 2.43e-23 GRB10-interacting GYF protein 2 (PERQ amino acid-rich with GYF domain-containing protein 2) (Trinucleotide repeat-containing gene 15 protein) Homo sapiens (Human) adult locomotory behavior [GO:0008344]; feeding behavior [GO:0007631]; homeostasis of number of cells within a tissue [GO:0048873]; insulin-like growth factor receptor signaling pathway [GO:0048009]; mitotic G1 DNA damage checkpoint signaling [GO:0031571]; mRNA destabilization [GO:0061157]; multicellular organism growth [GO:0035264]; musculoskeletal movement [GO:0050881]; negative regulation of translation [GO:0017148]; neuromuscular process controlling balance [GO:0050885]; post-embryonic development [GO:0009791]; post-transcriptional gene silencing [GO:0016441]; protein metabolic process [GO:0019538]; spinal cord motor neuron differentiation [GO:0021522] GO:0003723; GO:0005768; GO:0005783; GO:0005794; GO:0005829; GO:0007631; GO:0008344; GO:0009791; GO:0010494; GO:0016020; GO:0016441; GO:0017148; GO:0019538; GO:0021522; GO:0031571; GO:0031982; GO:0032991; GO:0035264; GO:0043204; GO:0045296; GO:0048009; GO:0048873; GO:0050881; GO:0050885; GO:0061157; GO:0070064; GO:1990635 13804 XM_044313043.1 163 140 137 5 32 Q28EX9 1.05e-125 Ubiquitin-like domain-containing CTD phosphatase 1 (EC 3.1.3.16) (Nuclear proteasome inhibitor UBLCP1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005634; GO:0017018 13805 XM_029344878.2 3157 3031 1666 2371 2767 O88413 7.75e-136 Tubby-related protein 3 (Tubby-like protein 3) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; bone development [GO:0060348]; brain development [GO:0007420]; bronchus morphogenesis [GO:0060434]; central nervous system neuron differentiation [GO:0021953]; dorsal/ventral neural tube patterning [GO:0021904]; embryonic camera-type eye development [GO:0031076]; embryonic digit morphogenesis [GO:0042733]; embryonic neurocranium morphogenesis [GO:0048702]; ganglion development [GO:0061548]; limb development [GO:0060173]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:1901621]; negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning [GO:0021914]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; neural tube formation [GO:0001841]; protein localization to cilium [GO:0061512]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; regulation of smoothened signaling pathway [GO:0008589]; smoothened signaling pathway [GO:0007224]; smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] GO:0001664; GO:0001841; GO:0001843; GO:0005576; GO:0005634; GO:0005654; GO:0005730; GO:0005886; GO:0005929; GO:0005930; GO:0007224; GO:0007420; GO:0008277; GO:0008589; GO:0009952; GO:0019899; GO:0021904; GO:0021914; GO:0021915; GO:0021953; GO:0031076; GO:0035091; GO:0042733; GO:0044877; GO:0045879; GO:0048702; GO:0060173; GO:0060348; GO:0060434; GO:0060831; GO:0061512; GO:0061548; GO:0097546; GO:0097731; GO:0120160; GO:1901621 13806 XM_029327456.2 1724 1511 942 1660 1517 F1SS88 0 Cilia- and flagella-associated protein 52 (WD repeat-containing protein 16) Sus scrofa (Pig) cilium assembly [GO:0060271]; establishment of left/right asymmetry [GO:0061966]; flagellated sperm motility [GO:0030317] GO:0005879; GO:0005930; GO:0030317; GO:0060271; GO:0061966; GO:0097729 13807 XM_044318507.1 259 396 14 677 652 Q924L9 4.73e-144 Folylpolyglutamate synthase, mitochondrial (EC 6.3.2.17) (Folylpoly-gamma-glutamate synthetase) (FPGS) (Tetrahydrofolate synthase) (Tetrahydrofolylpolyglutamate synthase) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) one-carbon metabolic process [GO:0006730] GO:0004326; GO:0005524; GO:0005743; GO:0005759; GO:0006730; GO:0046872 13808 XM_044323877.1 3 0 0 8 22 NA NA NA NA NA NA 13809 XM_029335029.2 404 451 202 319 577 NA NA NA NA NA NA 13810 XM_044307891.1 1216 1443 850 1172 1121 Q6DIP8 2.02e-95 Cotranscriptional regulator FAM172A homolog (Protein FAM172A) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0005634; GO:0005737; GO:0006397; GO:0008380 13811 XM_044314548.1 0 0 1 2 7 Q8IWT6 6.67e-73 Volume-regulated anion channel subunit LRRC8A (Leucine-rich repeat-containing protein 8A) (HsLRRC8A) (Swelling protein 1) Homo sapiens (Human) anion transmembrane transport [GO:0098656]; anion transport [GO:0006820]; aspartate transmembrane transport [GO:0015810]; cell volume homeostasis [GO:0006884]; cellular glucose homeostasis [GO:0001678]; chloride transmembrane transport [GO:1902476]; cyclic-GMP-AMP transmembrane import across plasma membrane [GO:0140361]; positive regulation of insulin secretion [GO:0032024]; positive regulation of myoblast differentiation [GO:0045663]; pre-B cell differentiation [GO:0002329]; protein hexamerization [GO:0034214]; response to osmotic stress [GO:0006970]; spermatogenesis [GO:0007283]; taurine transport [GO:0015734] GO:0001678; GO:0002329; GO:0005225; GO:0005765; GO:0005886; GO:0006820; GO:0006884; GO:0006970; GO:0007283; GO:0009986; GO:0015734; GO:0015810; GO:0016020; GO:0032024; GO:0034214; GO:0034702; GO:0042802; GO:0045663; GO:0098656; GO:0140360; GO:0140361; GO:1902476 13812 XR_006395869.1 54 20 22 57 48 NA NA NA NA NA NA 13813 XR_006395317.1 107 141 57 298 133 P35858 2.07e-26 Insulin-like growth factor-binding protein complex acid labile subunit (ALS) Homo sapiens (Human) cell adhesion [GO:0007155]; signal transduction [GO:0007165] GO:0005520; GO:0005576; GO:0005615; GO:0007155; GO:0007165; GO:0031012; GO:0042567; GO:0070062 13814 XR_006395317.1 107 141 57 298 133 P35858 3.56e-22 Insulin-like growth factor-binding protein complex acid labile subunit (ALS) Homo sapiens (Human) cell adhesion [GO:0007155]; signal transduction [GO:0007165] GO:0005520; GO:0005576; GO:0005615; GO:0007155; GO:0007165; GO:0031012; GO:0042567; GO:0070062 13815 XM_044316352.1 16 12 8 4 23 NA NA NA NA NA NA 13816 XR_006393471.1 0 0 0 0 7 NA NA NA NA NA NA 13817 XM_044319047.1 0 0 96 0 0 NA NA NA NA NA NA 13818 XM_044325289.1 687 557 289 549 574 P49760 4.68e-164 Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2) Homo sapiens (Human) negative regulation of gluconeogenesis [GO:0045721]; peptidyl-tyrosine phosphorylation [GO:0018108]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of RNA splicing [GO:0043484]; response to ionizing radiation [GO:0010212] GO:0004674; GO:0004712; GO:0004713; GO:0005524; GO:0005634; GO:0005654; GO:0006468; GO:0010212; GO:0016604; GO:0016607; GO:0018108; GO:0042802; GO:0043484; GO:0045721; GO:0046777; GO:0106310 13819 XM_029335686.2 9 5 4 7 4 NA NA NA NA NA NA 13820 XM_044323285.1 9875 11072 6278 10080 6005 NA NA NA NA NA NA 13821 XM_029331921.2 1212 596 522 875 948 Q5F362 7.06e-99 Cell cycle control protein 50A (P4-ATPase flippase complex beta subunit TMEM30A) (Transmembrane protein 30A) Gallus gallus (Chicken) phospholipid translocation [GO:0045332] GO:0001750; GO:0001917; GO:0005783; GO:0005794; GO:0005886; GO:0016324; GO:0030658; GO:0045332; GO:1990531 13822 XM_029352620.2 53 112 0 56 45 NA NA NA NA NA NA 13823 XM_029358017.2 710 649 323 598 489 NA NA NA NA NA NA 13824 XM_029340091.2 650 593 464 870 859 Q12874 0 Splicing factor 3A subunit 3 (SF3a60) (Spliceosome-associated protein 61) (SAP 61) Homo sapiens (Human) mRNA 3'-splice site recognition [GO:0000389]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing, via transesterification reactions [GO:0000375]; U2-type prespliceosome assembly [GO:1903241] GO:0000375; GO:0000389; GO:0000398; GO:0003723; GO:0005634; GO:0005654; GO:0005681; GO:0005684; GO:0005686; GO:0006397; GO:0008270; GO:0016607; GO:0071005; GO:0071013; GO:1903241 13825 XR_006393898.1 41 2 25 5 151 NA NA NA NA NA NA 13826 XM_029348804.2 519 480 346 390 351 NA NA NA NA NA NA 13827 XM_029335212.2 59 43 32 33 52 Q9NPC2 8.07e-30 Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3) (Two pore potassium channel KT3.2) (Two pore K(+) channel KT3.2) Homo sapiens (Human) potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; stabilization of membrane potential [GO:0030322] GO:0005267; GO:0005886; GO:0006813; GO:0008021; GO:0015271; GO:0022841; GO:0030322; GO:0071805; GO:1990573 13828 XM_029340468.2 524 422 324 441 550 Q62070 3.32e-85 Serine/threonine-protein kinase pim-2 (EC 2.7.11.1) Mus musculus (Mouse) apoptotic mitochondrial changes [GO:0008637]; apoptotic process [GO:0006915]; G1/S transition of mitotic cell cycle [GO:0000082]; macroautophagy [GO:0016236]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein binding [GO:0032091]; positive regulation of autophagy [GO:0010508]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of mitotic cell cycle [GO:0007346] GO:0000082; GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0006468; GO:0006915; GO:0007346; GO:0008285; GO:0008637; GO:0010508; GO:0016236; GO:0016239; GO:0032091; GO:0043066; GO:0043123; GO:0045893; GO:0046777; GO:0050821; GO:0106310 13829 XR_006391499.1 55 49 4 19 27 NA NA NA NA NA NA 13830 XM_044322078.1 67 0 11 5 0 Q8IZH2 0 5'-3' exoribonuclease 1 (EC 3.1.13.-) (Strand-exchange protein 1 homolog) Homo sapiens (Human) cellular response to cycloheximide [GO:0071409]; cellular response to puromycin [GO:1905795]; histone mRNA catabolic process [GO:0071044]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of translation [GO:0017148]; nuclear mRNA surveillance [GO:0071028]; nuclear-transcribed mRNA catabolic process [GO:0000956]; response to testosterone [GO:0033574]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; rRNA catabolic process [GO:0016075] GO:0000932; GO:0000956; GO:0002151; GO:0003723; GO:0004534; GO:0005634; GO:0005829; GO:0005886; GO:0016020; GO:0016075; GO:0017148; GO:0030425; GO:0032211; GO:0033574; GO:0043025; GO:0045202; GO:0051880; GO:0070034; GO:0071028; GO:0071044; GO:0071409; GO:0090503; GO:1905795 13831 XR_006392957.1 41 2 25 5 151 NA NA NA NA NA NA 13832 XM_029333626.2 0 107 0 112 29 P16066 3.59e-67 Atrial natriuretic peptide receptor 1 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type A) (ANP-A) (ANPR-A) (NPR-A) (Guanylate cyclase A) (GC-A) Homo sapiens (Human) blood vessel diameter maintenance [GO:0097746]; body fluid secretion [GO:0007589]; cell surface receptor signaling pathway [GO:0007166]; cGMP biosynthetic process [GO:0006182]; cGMP-mediated signaling [GO:0019934]; dopamine metabolic process [GO:0042417]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell growth [GO:0030308]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of cGMP-mediated signaling [GO:0010753]; positive regulation of renal sodium excretion [GO:0035815]; positive regulation of urine volume [GO:0035810]; protein phosphorylation [GO:0006468]; receptor guanylyl cyclase signaling pathway [GO:0007168]; regulation of blood pressure [GO:0008217]; regulation of vascular permeability [GO:0043114]; signal transduction [GO:0007165] GO:0001653; GO:0004383; GO:0004672; GO:0005524; GO:0005525; GO:0005886; GO:0006182; GO:0006468; GO:0007165; GO:0007166; GO:0007168; GO:0007589; GO:0008217; GO:0008528; GO:0010753; GO:0016525; GO:0016941; GO:0017046; GO:0019934; GO:0030308; GO:0035810; GO:0035815; GO:0042417; GO:0042562; GO:0043114; GO:0043235; GO:0048662; GO:0097746; GO:1990620 13833 XM_029328969.2 419 385 191 258 12 P02594 5.63e-42 Calmodulin (CaM) Electrophorus electricus (Electric eel) (Gymnotus electricus) NA GO:0005509 13834 XM_044307536.1 37 102 225 261 183 Q1PSW8 1.43e-24 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (mLin41) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Mus musculus (Mouse) 3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to organic substance [GO:0071310]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA processing [GO:0035196]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; post-transcriptional regulation of gene expression [GO:0010608]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein metabolic process [GO:0051246]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0001843; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0010608; GO:0017148; GO:0021915; GO:0030371; GO:0035196; GO:0035198; GO:0035278; GO:0043161; GO:0051246; GO:0051865; GO:0060964; GO:0061158; GO:0061630; GO:0071310; GO:0072089; GO:2000177; GO:2000637 13835 XM_029357595.2 2010 1718 1195 2494 2585 Q8R4S6 2.16e-31 Aryl hydrocarbon receptor (Ah receptor) (AhR) Mus musculus castaneus (Southeastern Asian house mouse) cell cycle [GO:0007049]; cellular response to 3-methylcholanthrene [GO:1904682]; circadian regulation of gene expression [GO:0032922]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of T cell mediated immune response to tumor cell [GO:0002841]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of adaptive immune response [GO:0002819]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; response to xenobiotic stimulus [GO:0009410]; transcription by RNA polymerase II [GO:0006366] GO:0000976; GO:0002819; GO:0002841; GO:0004879; GO:0005634; GO:0005737; GO:0006355; GO:0006357; GO:0006366; GO:0007049; GO:0009410; GO:0032922; GO:0034751; GO:0034753; GO:0042803; GO:0045892; GO:0045944; GO:0046982; GO:0070888; GO:1904682; GO:1990837 13836 XM_044309172.1 5 38 4 9 7 NA NA NA NA NA NA 13837 XM_044312784.1 394 213 75 243 379 NA NA NA NA NA NA 13838 XM_029342857.2 159 155 149 162 184 NA NA NA NA NA NA 13839 XM_044316041.1 720 421 321 707 908 NA NA NA NA NA NA 13840 XM_029331687.2 248 143 114 32 168 NA NA NA NA NA NA 13841 XM_029333877.2 30 30 20 26 24 NA NA NA NA NA NA 13842 XR_006393619.1 16 42 33 11 32 NA NA NA NA NA NA 13843 XM_044314594.1 62 42 50 96 105 Q6IQE9 3.79e-85 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6 (EC 1.14.11.-) (Alkylated DNA repair protein alkB homolog 6) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005634; GO:0005737; GO:0046872; GO:0051213 13844 XM_044315728.1 83 60 69 38 107 NA NA NA NA NA NA 13845 XM_044318710.1 358 609 120 186 209 NA NA NA NA NA NA 13846 XM_029338259.2 598 560 403 355 331 Q68CL5 7.02e-69 Tubulin polyglutamylase complex subunit 2 (PGs2) Homo sapiens (Human) protein polyglutamylation [GO:0018095] GO:0005737; GO:0005815; GO:0005874; GO:0018095 13847 XM_029333688.2 39 0 0 39 79 O96952 2.43e-24 Thioredoxin (Trx) Geodia cydonium (Sponge) NA GO:0005737; GO:0015035 13848 XM_044309303.1 2 4 27 17 49 NA NA NA NA NA NA 13849 XM_029337014.2 88 0 0 42 142 NA NA NA NA NA NA 13850 XM_044320685.1 10 0 0 0 57 A2AJ76 1.8e-30 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 13851 XM_029324706.2 72 19 20 42 2 P48630 6.08e-115 Omega-6 fatty acid desaturase, endoplasmic reticulum isozyme 1 (EC 1.14.19.-) Glycine max (Soybean) (Glycine hispida) unsaturated fatty acid biosynthetic process [GO:0006636] GO:0005789; GO:0006636; GO:0016491 13852 XM_029349565.2 275 438 696 851 880 Q9VBW3 1.71e-80 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 13853 XM_044325335.1 14 6 4 19 0 A6QLU6 8.13e-53 Adhesion G-protein coupled receptor D1 (G-protein coupled receptor 133) Bos taurus (Bovine) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0005886; GO:0007166; GO:0007186; GO:0007189 13854 XM_029332111.2 647 237 273 669 380 P56192 0 Methionine--tRNA ligase, cytoplasmic (EC 6.1.1.10) (Methionyl-tRNA synthetase) (MetRS) Homo sapiens (Human) cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; methionyl-tRNA aminoacylation [GO:0006431]; positive regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901838]; rRNA transcription [GO:0009303]; tRNA aminoacylation for protein translation [GO:0006418] GO:0000049; GO:0004825; GO:0005524; GO:0005730; GO:0005737; GO:0005829; GO:0006418; GO:0006431; GO:0009303; GO:0016020; GO:0017101; GO:0036120; GO:0070062; GO:0071364; GO:1901838 13855 XM_044308914.1 12 7 7 7 68 NA NA NA NA NA NA 13856 XR_003827281.2 936 1 8 33 53 NA NA NA NA NA NA 13857 XM_044310194.1 21 0 0 17 17 P10394 2.37e-31 Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 13858 XM_029355392.2 14 0 0 28 2 NA NA NA NA NA NA 13859 XM_044320148.1 0 65 29 16 28 P07992 5.13e-68 DNA excision repair protein ERCC-1 Homo sapiens (Human) cell population proliferation [GO:0008283]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; embryonic organ development [GO:0048568]; interstrand cross-link repair [GO:0036297]; isotype switching [GO:0045190]; male gonad development [GO:0008584]; meiotic mismatch repair [GO:0000710]; mitotic recombination [GO:0006312]; multicellular organism aging [GO:0010259]; multicellular organism growth [GO:0035264]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of telomere maintenance [GO:0032205]; nucleotide-excision repair [GO:0006289]; oogenesis [GO:0048477]; positive regulation of t-circle formation [GO:1904431]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; post-embryonic hemopoiesis [GO:0035166]; pyrimidine dimer repair by nucleotide-excision repair [GO:0000720]; replicative senescence [GO:0090399]; response to cadmium ion [GO:0046686]; response to immobilization stress [GO:0035902]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to sucrose [GO:0009744]; response to X-ray [GO:0010165]; spermatogenesis [GO:0007283]; syncytium formation [GO:0006949]; t-circle formation [GO:0090656]; telomeric DNA-containing double minutes formation [GO:0061819]; UV protection [GO:0009650]; UV-damage excision repair [GO:0070914] GO:0000109; GO:0000110; GO:0000710; GO:0000720; GO:0000781; GO:0001094; GO:0003684; GO:0003697; GO:0005654; GO:0005737; GO:0006281; GO:0006289; GO:0006303; GO:0006312; GO:0006949; GO:0006979; GO:0007283; GO:0007584; GO:0008022; GO:0008283; GO:0008584; GO:0009650; GO:0009744; GO:0010165; GO:0010259; GO:0019904; GO:0032205; GO:0035166; GO:0035264; GO:0035902; GO:0036297; GO:0045190; GO:0046686; GO:0048477; GO:0048568; GO:0060261; GO:0061819; GO:0070522; GO:0070914; GO:0090399; GO:0090656; GO:1904431; GO:1905765; GO:1990841 13860 XM_044320148.1 0 65 29 16 28 P07992 5.13e-68 DNA excision repair protein ERCC-1 Homo sapiens (Human) cell population proliferation [GO:0008283]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; embryonic organ development [GO:0048568]; interstrand cross-link repair [GO:0036297]; isotype switching [GO:0045190]; male gonad development [GO:0008584]; meiotic mismatch repair [GO:0000710]; mitotic recombination [GO:0006312]; multicellular organism aging [GO:0010259]; multicellular organism growth [GO:0035264]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of telomere maintenance [GO:0032205]; nucleotide-excision repair [GO:0006289]; oogenesis [GO:0048477]; positive regulation of t-circle formation [GO:1904431]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; post-embryonic hemopoiesis [GO:0035166]; pyrimidine dimer repair by nucleotide-excision repair [GO:0000720]; replicative senescence [GO:0090399]; response to cadmium ion [GO:0046686]; response to immobilization stress [GO:0035902]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to sucrose [GO:0009744]; response to X-ray [GO:0010165]; spermatogenesis [GO:0007283]; syncytium formation [GO:0006949]; t-circle formation [GO:0090656]; telomeric DNA-containing double minutes formation [GO:0061819]; UV protection [GO:0009650]; UV-damage excision repair [GO:0070914] GO:0000109; GO:0000110; GO:0000710; GO:0000720; GO:0000781; GO:0001094; GO:0003684; GO:0003697; GO:0005654; GO:0005737; GO:0006281; GO:0006289; GO:0006303; GO:0006312; GO:0006949; GO:0006979; GO:0007283; GO:0007584; GO:0008022; GO:0008283; GO:0008584; GO:0009650; GO:0009744; GO:0010165; GO:0010259; GO:0019904; GO:0032205; GO:0035166; GO:0035264; GO:0035902; GO:0036297; GO:0045190; GO:0046686; GO:0048477; GO:0048568; GO:0060261; GO:0061819; GO:0070522; GO:0070914; GO:0090399; GO:0090656; GO:1904431; GO:1905765; GO:1990841 13861 XM_044315576.1 11 25 3 4 3 NA NA NA NA NA NA 13862 XM_044314206.1 0 6 22 14 24 NA NA NA NA NA NA 13863 XM_044317581.1 12 0 1 0 0 NA NA NA NA NA NA 13864 XM_029358316.2 1171 955 744 1187 701 Q6DJ06 5.17e-54 LIM domain transcription factor LMO4.2 (LIM domain only protein 4.2) (LMO-4.2) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell differentiation [GO:0030154]; gastrulation [GO:0007369]; mesoderm development [GO:0007498]; negative regulation of neuron differentiation [GO:0045665]; nervous system development [GO:0007399]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0003712; GO:0007369; GO:0007399; GO:0007498; GO:0030154; GO:0045665; GO:0045944; GO:0046872 13865 XM_044315381.1 117 4 25 10 477 NA NA NA NA NA NA 13866 XM_029327160.2 252 115 90 95 223 O60268 7.63e-21 Uncharacterized protein KIAA0513 Homo sapiens (Human) NA GO:0005737 13867 XM_044314402.1 191 9 71 307 167 P70195 4.03e-86 Proteasome subunit beta type-7 (EC 3.4.25.1) (Macropain chain Z) (Multicatalytic endopeptidase complex chain Z) (Proteasome subunit Z) Mus musculus (Mouse) proteasomal protein catabolic process [GO:0010498] GO:0000502; GO:0004175; GO:0004298; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005839; GO:0010498; GO:0016604; GO:0019774 13868 XM_044314402.1 191 9 71 307 167 P70195 4.03e-86 Proteasome subunit beta type-7 (EC 3.4.25.1) (Macropain chain Z) (Multicatalytic endopeptidase complex chain Z) (Proteasome subunit Z) Mus musculus (Mouse) proteasomal protein catabolic process [GO:0010498] GO:0000502; GO:0004175; GO:0004298; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005839; GO:0010498; GO:0016604; GO:0019774 13869 XM_044314402.1 191 9 71 307 167 P70195 4.03e-86 Proteasome subunit beta type-7 (EC 3.4.25.1) (Macropain chain Z) (Multicatalytic endopeptidase complex chain Z) (Proteasome subunit Z) Mus musculus (Mouse) proteasomal protein catabolic process [GO:0010498] GO:0000502; GO:0004175; GO:0004298; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005839; GO:0010498; GO:0016604; GO:0019774 13870 XM_044307712.1 0 0 0 26 103 NA NA NA NA NA NA 13871 XR_006393906.1 41 2 25 5 151 NA NA NA NA NA NA 13872 XM_029333006.2 30 20 12 27 10 NA NA NA NA NA NA 13873 XM_044320669.1 116 5 38 10 238 P35556 2.91e-66 Fibrillin-2 [Cleaved into: Placensin] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030023; GO:0030326; GO:0030501; GO:0031012; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 13874 XM_044320669.1 116 5 38 10 238 P35556 1.6e-51 Fibrillin-2 [Cleaved into: Placensin] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030023; GO:0030326; GO:0030501; GO:0031012; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 13875 XM_044320669.1 116 5 38 10 238 P35556 1.47e-41 Fibrillin-2 [Cleaved into: Placensin] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030023; GO:0030326; GO:0030501; GO:0031012; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 13876 XM_044320669.1 116 5 38 10 238 P35556 5.76e-40 Fibrillin-2 [Cleaved into: Placensin] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030023; GO:0030326; GO:0030501; GO:0031012; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 13877 XM_044320669.1 116 5 38 10 238 P35556 5.94e-37 Fibrillin-2 [Cleaved into: Placensin] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030023; GO:0030326; GO:0030501; GO:0031012; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 13878 XM_044320669.1 116 5 38 10 238 P35556 1.86e-32 Fibrillin-2 [Cleaved into: Placensin] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030023; GO:0030326; GO:0030501; GO:0031012; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 13879 XM_044320669.1 116 5 38 10 238 P35556 4.67e-31 Fibrillin-2 [Cleaved into: Placensin] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030023; GO:0030326; GO:0030501; GO:0031012; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 13880 XM_044320669.1 116 5 38 10 238 P35556 8.81e-31 Fibrillin-2 [Cleaved into: Placensin] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030023; GO:0030326; GO:0030501; GO:0031012; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 13881 XM_044320669.1 116 5 38 10 238 P35556 5.57e-30 Fibrillin-2 [Cleaved into: Placensin] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030023; GO:0030326; GO:0030501; GO:0031012; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 13882 XM_044320669.1 116 5 38 10 238 P35556 1.51e-28 Fibrillin-2 [Cleaved into: Placensin] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030023; GO:0030326; GO:0030501; GO:0031012; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 13883 XM_044320669.1 116 5 38 10 238 P35556 1.75e-28 Fibrillin-2 [Cleaved into: Placensin] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030023; GO:0030326; GO:0030501; GO:0031012; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 13884 XM_044320669.1 116 5 38 10 238 P35556 1.43e-25 Fibrillin-2 [Cleaved into: Placensin] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030023; GO:0030326; GO:0030501; GO:0031012; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 13885 XM_044320669.1 116 5 38 10 238 P35556 5.52e-25 Fibrillin-2 [Cleaved into: Placensin] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030023; GO:0030326; GO:0030501; GO:0031012; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 13886 XM_044320669.1 116 5 38 10 238 P35556 2.9e-23 Fibrillin-2 [Cleaved into: Placensin] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030023; GO:0030326; GO:0030501; GO:0031012; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 13887 XM_029335741.2 0 60 15 127 0 Q2KIP6 4.26e-23 Kappa-type opioid receptor (K-OR-1) (KOR-1) Bos taurus (Bovine) adenylate cyclase-inhibiting opioid receptor signaling pathway [GO:0031635]; defense response to virus [GO:0051607]; G protein-coupled opioid receptor signaling pathway [GO:0038003]; immune response [GO:0006955]; locomotory behavior [GO:0007626]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; regulation of saliva secretion [GO:0046877]; sensory perception of pain [GO:0019233] GO:0004930; GO:0004985; GO:0005654; GO:0005829; GO:0005886; GO:0006955; GO:0007200; GO:0007218; GO:0007626; GO:0016020; GO:0019233; GO:0031635; GO:0038003; GO:0038048; GO:0042277; GO:0042923; GO:0043005; GO:0046877; GO:0051607 13888 XM_044326977.1 273 175 108 222 137 Q28107 1.97e-24 Coagulation factor V (Activated protein C cofactor) [Cleaved into: Coagulation factor V heavy chain; Coagulation factor V light chain] Bos taurus (Bovine) blood circulation [GO:0008015]; blood coagulation [GO:0007596] GO:0005507; GO:0005576; GO:0007596; GO:0008015; GO:0031091 13889 XM_029343029.2 1616 1570 936 1537 1957 Q28IH8 8.14e-24 Cilia- and flagella-associated protein 36 (Coiled-coil domain-containing protein 104) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005634; GO:0005737; GO:0031514 13890 XM_044314207.1 140 152 148 292 281 Q96AY4 4.97e-168 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13891 XM_044314207.1 140 152 148 292 281 Q96AY4 5.95e-153 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13892 XM_044314207.1 140 152 148 292 281 Q96AY4 1.16e-133 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13893 XM_044314207.1 140 152 148 292 281 Q96AY4 7.1e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13894 XR_006393255.1 149 114 67 137 128 NA NA NA NA NA NA 13895 XM_029358321.2 426 387 415 779 411 NA NA NA NA NA NA 13896 XM_044311802.1 159 2278 1471 1355 1822 NA NA NA NA NA NA 13897 XM_029327230.2 9 16 12 10 15 NA NA NA NA NA NA 13898 XM_044327650.1 0 1 5 8 208 NA NA NA NA NA NA 13899 XM_029335890.2 809 415 483 725 887 P97275 0 Alkyldihydroxyacetonephosphate synthase, peroxisomal (Alkyl-DHAP synthase) (EC 2.5.1.26) (Alkylglycerone-phosphate synthase) Cavia porcellus (Guinea pig) ether lipid biosynthetic process [GO:0008611] GO:0005730; GO:0005777; GO:0005778; GO:0008609; GO:0008611; GO:0071949 13900 XM_044325201.1 0 0 10 0 222 NA NA NA NA NA NA 13901 XM_029334627.2 306 166 190 221 275 NA NA NA NA NA NA 13902 XM_029351063.2 326 56 70 228 259 Q61072 2.39e-60 Disintegrin and metalloproteinase domain-containing protein 9 (ADAM 9) (EC 3.4.24.-) (Meltrin-gamma) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) Mus musculus (Mouse) amyloid precursor protein catabolic process [GO:0042987]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell migration [GO:0016477]; cell-cell adhesion mediated by integrin [GO:0033631]; cell-matrix adhesion [GO:0007160]; cellular response to lipopolysaccharide [GO:0071222]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; monocyte activation [GO:0042117]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of macrophage fusion [GO:0034241]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of protein secretion [GO:0050714]; protein processing [GO:0016485]; response to calcium ion [GO:0051592]; response to glucocorticoid [GO:0051384]; response to hydrogen peroxide [GO:0042542]; response to manganese ion [GO:0010042]; response to tumor necrosis factor [GO:0034612]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0004222; GO:0005080; GO:0005178; GO:0005518; GO:0005615; GO:0005737; GO:0005886; GO:0006509; GO:0007155; GO:0007160; GO:0007179; GO:0008237; GO:0009897; GO:0009986; GO:0010042; GO:0016323; GO:0016477; GO:0016485; GO:0017124; GO:0030335; GO:0031293; GO:0033627; GO:0033630; GO:0033631; GO:0034241; GO:0034612; GO:0042117; GO:0042542; GO:0042987; GO:0043236; GO:0043406; GO:0046872; GO:0050714; GO:0051044; GO:0051384; GO:0051549; GO:0051592; GO:0071222; GO:1902945 13903 XM_044309045.1 77 16 87 49 63 Q9Z2I4 1.26e-31 Roundabout homolog 3 (Retinoblastoma-inhibiting gene 1 protein) (Rig-1) Mus musculus (Mouse) axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; neuron migration [GO:0001764] GO:0001764; GO:0005886; GO:0007411; GO:0016199; GO:0030424 13904 XM_044309045.1 77 16 87 49 63 Q9Z2I4 9.24e-24 Roundabout homolog 3 (Retinoblastoma-inhibiting gene 1 protein) (Rig-1) Mus musculus (Mouse) axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; neuron migration [GO:0001764] GO:0001764; GO:0005886; GO:0007411; GO:0016199; GO:0030424 13905 XM_044309045.1 77 16 87 49 63 Q9Z2I4 1.05e-21 Roundabout homolog 3 (Retinoblastoma-inhibiting gene 1 protein) (Rig-1) Mus musculus (Mouse) axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; neuron migration [GO:0001764] GO:0001764; GO:0005886; GO:0007411; GO:0016199; GO:0030424 13906 XR_006396443.1 165 82 116 107 233 NA NA NA NA NA NA 13907 XM_029356187.2 47 0 0 11 32 P19019 7.02e-61 Gamma-aminobutyric acid receptor subunit beta-3 (GABA(A) receptor subunit beta-3) Gallus gallus (Chicken) chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid signaling pathway [GO:0007214]; inhibitory synapse assembly [GO:1904862]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165] GO:0004890; GO:0005231; GO:0005886; GO:0007165; GO:0007214; GO:0007268; GO:0022851; GO:0030594; GO:0030659; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:1902476; GO:1902711; GO:1904315; GO:1904862 13908 XM_044311857.1 15 0 0 0 0 NA NA NA NA NA NA 13909 XR_006394428.1 9 8 0 11 10 NA NA NA NA NA NA 13910 XM_044324570.1 9 0 11 10 7 NA NA NA NA NA NA 13911 XM_029329099.2 598 220 206 288 103 Q96242 4.59e-29 Allene oxide synthase, chloroplastic (EC 4.2.1.92) (Cytochrome P450 74A) (Hydroperoxide dehydrase) Arabidopsis thaliana (Mouse-ear cress) defense response [GO:0006952]; defense response to fungus [GO:0050832]; epoxygenase P450 pathway [GO:0019373]; fatty acid biosynthetic process [GO:0006633]; jasmonic acid biosynthetic process [GO:0009695]; oxylipin biosynthetic process [GO:0031408]; oxylipin metabolic process [GO:0031407]; response to fungus [GO:0009620]; response to jasmonic acid [GO:0009753]; response to wounding [GO:0009611]; sterol metabolic process [GO:0016125] GO:0004497; GO:0005506; GO:0005739; GO:0006633; GO:0006952; GO:0009507; GO:0009534; GO:0009535; GO:0009536; GO:0009579; GO:0009611; GO:0009620; GO:0009695; GO:0009753; GO:0009941; GO:0009978; GO:0010287; GO:0016125; GO:0016491; GO:0016705; GO:0019373; GO:0019825; GO:0020037; GO:0031407; GO:0031408; GO:0050832 13912 XM_044306934.1 2 0 7 0 14 NA NA NA NA NA NA 13913 XM_029350693.2 198 97 15 130 117 NA NA NA NA NA NA 13914 XM_029345942.2 46 59 11 0 0 NA NA NA NA NA NA 13915 XM_029331533.2 0 39 0 0 60 NA NA NA NA NA NA 13916 XR_006392546.1 0 2 2 0 10 NA NA NA NA NA NA 13917 XM_044322699.1 62 44 169 42 225 NA NA NA NA NA NA 13918 XM_044320022.1 0 1 0 4 10 NA NA NA NA NA NA 13919 XM_044322542.1 27 0 178 76 21 NA NA NA NA NA NA 13920 XM_044313804.1 0 15 0 0 22 NA NA NA NA NA NA 13921 XM_044328550.1 155 52 116 162 200 Q9CYU6 6.08e-47 Diphthine methyltransferase (EC 3.1.1.97) (Diphthamide biosynthesis protein 7) (DPH7) (WD repeat-containing protein 85) Mus musculus (Mouse) peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183] GO:0005737; GO:0017183; GO:0061685 13922 XM_044319557.1 6 0 0 0 39 NA NA NA NA NA NA 13923 XM_044317224.1 36 137 72 145 55 O35231 9.97e-176 Kinesin-like protein KIFC3 Mus musculus (Mouse) epithelial cell-cell adhesion [GO:0090136]; Golgi organization [GO:0007030]; microtubule-based movement [GO:0007018]; microtubule-based process [GO:0007017]; zonula adherens maintenance [GO:0045218] GO:0005524; GO:0005794; GO:0005813; GO:0005871; GO:0005874; GO:0005915; GO:0007017; GO:0007018; GO:0007030; GO:0008017; GO:0008569; GO:0015630; GO:0030659; GO:0042802; GO:0045218; GO:0090136 13924 XM_029348083.2 223 165 94 276 359 NA NA NA NA NA NA 13925 XM_029355875.2 5027 4467 3166 5218 5639 Q9NQC3 2.07e-38 Reticulon-4 (Foocen) (Neurite outgrowth inhibitor) (Nogo protein) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5) Homo sapiens (Human) apoptotic process [GO:0006915]; axonal fasciculation [GO:0007413]; blastocyst formation [GO:0001825]; brain development [GO:0007420]; cardiac epithelial to mesenchymal transition [GO:0060317]; cell adhesion involved in sprouting angiogenesis [GO:0120078]; cell migration involved in vasculogenesis [GO:0035441]; cellular response to hypoxia [GO:0071456]; cellular sphingolipid homeostasis [GO:0090156]; central nervous system vasculogenesis [GO:0022009]; cerebral cortex radial glia-guided migration [GO:0021801]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum tubular network formation [GO:0071787]; endoplasmic reticulum tubular network membrane organization [GO:1990809]; endoplasmic reticulum tubular network organization [GO:0071786]; leukocyte migration involved in inflammatory response [GO:0002523]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of axon extension [GO:0030517]; negative regulation of cell growth [GO:0030308]; negative regulation of vasculogenesis [GO:2001213]; neuron differentiation [GO:0030182]; nuclear pore complex assembly [GO:0051292]; positive regulation of angiogenesis [GO:0045766]; positive regulation of artery morphogenesis [GO:1905653]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of ERBB3 signaling pathway [GO:1905580]; positive regulation of hepatocyte proliferation [GO:2000347]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of macrophage migration [GO:1905523]; positive regulation of mammary gland epithelial cell proliferation [GO:0033601]; positive regulation of neutrophil migration [GO:1902624]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to endoplasmic reticulum [GO:1905552]; positive regulation of Rac protein signal transduction [GO:0035022]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; protein localization to lysosome [GO:0061462]; protein stabilization [GO:0050821]; regulation of apoptotic process [GO:0042981]; regulation of branching morphogenesis of a nerve [GO:2000172]; regulation of cell migration [GO:0030334] GO:0001825; GO:0002523; GO:0003723; GO:0005635; GO:0005783; GO:0005789; GO:0005886; GO:0006915; GO:0007029; GO:0007413; GO:0007420; GO:0010634; GO:0014069; GO:0021801; GO:0022009; GO:0030054; GO:0030182; GO:0030308; GO:0030334; GO:0030517; GO:0031625; GO:0033601; GO:0034165; GO:0035022; GO:0035441; GO:0042803; GO:0042981; GO:0043005; GO:0045296; GO:0045766; GO:0046872; GO:0050804; GO:0050821; GO:0051292; GO:0051897; GO:0060317; GO:0060907; GO:0061462; GO:0070161; GO:0071456; GO:0071782; GO:0071786; GO:0071787; GO:0090156; GO:0098826; GO:0098978; GO:0120078; GO:1902430; GO:1902624; GO:1905523; GO:1905552; GO:1905580; GO:1905653; GO:1990809; GO:2000172; GO:2000347; GO:2001213 13926 XM_029339695.2 2098 2050 1392 1644 1782 NA NA NA NA NA NA 13927 XM_029324120.2 1090 297 589 358 404 NA NA NA NA NA NA 13928 XM_029339460.2 783 1220 607 1544 1286 D3Z8N4 3.79e-42 Kelch-like protein 20 Rattus norvegicus (Rat) Golgi to endosome transport [GO:0006895]; negative regulation of apoptotic process [GO:0043066]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K33-linked ubiquitination [GO:1990390]; protein transport [GO:0015031]; protein ubiquitination [GO:0016567] GO:0003779; GO:0004842; GO:0005737; GO:0005802; GO:0005829; GO:0006895; GO:0015031; GO:0016567; GO:0016605; GO:0019964; GO:0030424; GO:0030425; GO:0031463; GO:0043066; GO:0043161; GO:0048471; GO:1990390 13929 XM_029344625.2 290 193 18 192 163 NA NA NA NA NA NA 13930 XM_029351087.2 74 50 31 75 12 NA NA NA NA NA NA 13931 XM_044321105.1 1398 1143 663 1299 1083 Q8C6G8 0 WD repeat-containing protein 26 Mus musculus (Mouse) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] GO:0000151; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005829; GO:0034657; GO:0043161 13932 XM_029329265.2 0 0 0 22 0 P18130 7.37e-48 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) Bos taurus (Bovine) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of vasoconstriction [GO:0045907]; regulation of cardiac muscle contraction [GO:0055117] GO:0001996; GO:0004930; GO:0004937; GO:0005634; GO:0005737; GO:0005886; GO:0005901; GO:0007200; GO:0007204; GO:0007267; GO:0031965; GO:0043410; GO:0045907; GO:0046982; GO:0055117; GO:0071880 13933 XM_029355397.2 627 488 329 956 608 P57076 1.49e-128 Cilia- and flagella-associated protein 298 (Protein kurly homolog) Homo sapiens (Human) cilium assembly [GO:0060271]; regulation of cilium movement [GO:0003352] GO:0003352; GO:0005634; GO:0005829; GO:0005856; GO:0005929; GO:0060271 13934 XM_044324788.1 201 233 125 230 124 P35546 6.07e-82 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; anatomical structure morphogenesis [GO:0009653]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006919; GO:0007156; GO:0007158; GO:0007169; GO:0007399; GO:0009410; GO:0009653; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030182; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0098797; GO:2001241 13935 XM_029346878.2 16 0 26 9 99 NA NA NA NA NA NA 13936 XM_029349809.2 0 220 4 82 491 Q58A42 9e-93 Protein DD3-3 Dictyostelium discoideum (Social amoeba) NA GO:0016020 13937 XM_029349809.2 0 220 4 82 491 Q58A42 9e-93 Protein DD3-3 Dictyostelium discoideum (Social amoeba) NA GO:0016020 13938 XM_029351397.2 0 0 47 0 0 A0A1L8F5J9 2.8e-51 Glutamate receptor ionotropic, NMDA 1 (GluN1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1) Xenopus laevis (African clawed frog) response to zinc ion [GO:0010043] GO:0004972; GO:0005886; GO:0010043; GO:0017146; GO:0045211; GO:0046872 13939 XR_006393885.1 41 2 25 5 151 NA NA NA NA NA NA 13940 XM_044326570.1 49 46 61 61 131 Q9BXT6 5.34e-103 RNA helicase Mov10l1 (EC 3.6.4.13) (Moloney leukemia virus 10-like protein 1) (MOV10-like protein 1) Homo sapiens (Human) DNA methylation involved in gamete generation [GO:0043046]; germ cell development [GO:0007281]; male meiosis I [GO:0007141]; piRNA processing [GO:0034587]; RNA-mediated post-transcriptional gene silencing [GO:0035194]; spermatogenesis [GO:0007283] GO:0000287; GO:0003723; GO:0003724; GO:0005524; GO:0005829; GO:0007141; GO:0007281; GO:0007283; GO:0016887; GO:0034587; GO:0035194; GO:0043046; GO:0043186; GO:0071546 13941 XR_006393386.1 599 373 681 759 386 NA NA NA NA NA NA 13942 XM_044308326.1 515 309 223 304 645 B3DMA2 0 Acyl-CoA dehydrogenase family member 11 (ACAD-11) (EC 1.3.8.-) Rattus norvegicus (Rat) fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539] GO:0003995; GO:0004466; GO:0005634; GO:0005737; GO:0005739; GO:0005777; GO:0017099; GO:0031966; GO:0033539; GO:0050660; GO:0070991 13943 XM_044324772.1 80 48 6 65 0 NA NA NA NA NA NA 13944 XM_029332891.2 562 717 186 446 392 NA NA NA NA NA NA 13945 XR_006397074.1 226 121 48 81 598 NA NA NA NA NA NA 13946 XM_044322908.1 1503 525 713 752 786 Q9VLC0 1.47e-168 Vacuolar protein sorting-associated protein 54 (Protein scattered) Drosophila melanogaster (Fruit fly) acrosome assembly [GO:0001675]; endocytic recycling [GO:0032456]; Golgi to vacuole transport [GO:0006896]; protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147]; sperm individualization [GO:0007291]; spermatid nucleus elongation [GO:0007290] GO:0000138; GO:0000938; GO:0001675; GO:0005794; GO:0005829; GO:0006896; GO:0007290; GO:0007291; GO:0015031; GO:0019905; GO:0032456; GO:0042147 13947 XM_029338482.2 905 1055 1332 3141 1106 Q5TCZ1 1.28e-50 SH3 and PX domain-containing protein 2A (Adapter protein TKS5) (Five SH3 domain-containing protein) (SH3 multiple domains protein 1) (Tyrosine kinase substrate with five SH3 domains) Homo sapiens (Human) in utero embryonic development [GO:0001701]; osteoclast fusion [GO:0072675]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801] GO:0001701; GO:0002020; GO:0002102; GO:0005546; GO:0005737; GO:0005829; GO:0006801; GO:0010314; GO:0016176; GO:0032266; GO:0042554; GO:0042995; GO:0043325; GO:0070161; GO:0070273; GO:0072675 13948 XM_029334513.2 66 20 0 8 1 NA NA NA NA NA NA 13949 XM_029337357.2 76880 96149 69343 67968 49986 NA NA NA NA NA NA 13950 XR_006391619.1 0 0 6 0 0 NA NA NA NA NA NA 13951 XM_044327088.1 1087 875 32 1301 1580 Q75N90 8.63e-54 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 13952 XM_044327088.1 1087 875 32 1301 1580 Q75N90 6.74e-46 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 13953 XM_044327088.1 1087 875 32 1301 1580 Q75N90 9.58e-46 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 13954 XM_044327088.1 1087 875 32 1301 1580 Q75N90 1.35e-44 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 13955 XM_044327088.1 1087 875 32 1301 1580 Q75N90 6.19e-44 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 13956 XM_044327088.1 1087 875 32 1301 1580 Q75N90 3.09e-36 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 13957 XM_044327088.1 1087 875 32 1301 1580 Q75N90 4.69e-34 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 13958 XM_044327088.1 1087 875 32 1301 1580 Q75N90 2.95e-32 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 13959 XM_044327088.1 1087 875 32 1301 1580 Q75N90 4.36e-31 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 13960 XM_044327088.1 1087 875 32 1301 1580 Q75N90 1.6e-29 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 13961 XM_044327088.1 1087 875 32 1301 1580 Q75N90 5.35e-29 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 13962 XM_044327088.1 1087 875 32 1301 1580 Q75N90 7.12e-29 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 13963 XM_044327088.1 1087 875 32 1301 1580 Q75N90 6.33e-27 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 13964 XM_044327088.1 1087 875 32 1301 1580 Q75N90 1.74e-26 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 13965 XM_044327088.1 1087 875 32 1301 1580 Q75N90 1.55e-25 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 13966 XM_044327088.1 1087 875 32 1301 1580 Q75N90 1.85e-25 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 13967 XM_044327088.1 1087 875 32 1301 1580 Q75N90 1.39e-21 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 13968 XM_044327088.1 1087 875 32 1301 1580 Q75N90 3.55e-21 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 13969 XM_044327092.1 73 30 44 95 82 P48416 4.32e-74 Cytochrome P450 10 (EC 1.14.-.-) (CYPX) Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004497; GO:0005506; GO:0016705; GO:0020037 13970 XM_044321404.1 1 17 0 1 7 NA NA NA NA NA NA 13971 XM_029352259.2 3273 3960 1419 1689 1216 NA NA NA NA NA NA 13972 XM_029344017.2 49 526 218 271 264 P81117 2.75e-54 Nucleobindin-2 (DNA-binding protein NEFA) (Prepronesfatin) [Cleaved into: Nesfatin-1] Mus musculus (Mouse) cellular calcium ion homeostasis [GO:0006874]; insulin metabolic process [GO:1901142]; negative regulation of appetite [GO:0032099]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of glucagon secretion [GO:0070093]; negative regulation of insulin receptor signaling pathway [GO:0046627]; positive regulation of fatty acid oxidation [GO:0046321]; positive regulation of testosterone secretion [GO:2000845]; small GTPase mediated signal transduction [GO:0007264] GO:0001965; GO:0003677; GO:0005085; GO:0005164; GO:0005509; GO:0005615; GO:0005634; GO:0005640; GO:0005737; GO:0005783; GO:0005793; GO:0005794; GO:0005797; GO:0006874; GO:0007264; GO:0032099; GO:0043204; GO:0043951; GO:0045599; GO:0046321; GO:0046627; GO:0070093; GO:1901142; GO:2000845 13973 XR_006394832.1 0 3 3 1 14 NA NA NA NA NA NA 13974 XM_029335165.2 544 286 196 452 314 A2A870 2e-65 Fas-binding factor 1 (FBF-1) Mus musculus (Mouse) apical junction assembly [GO:0043297]; cilium assembly [GO:0060271]; establishment of epithelial cell polarity [GO:0090162] GO:0000922; GO:0005737; GO:0005813; GO:0005814; GO:0036064; GO:0043296; GO:0043297; GO:0045095; GO:0060271; GO:0090162; GO:0097539 13975 XM_029335679.2 30 60 30 30 7 P07314 1.56e-135 Glutathione hydrolase 1 proenzyme (EC 3.4.19.13) (Gamma-glutamyltransferase 1) (Gamma-glutamyltranspeptidase 1) (GGT 1) (EC 2.3.2.2) (Leukotriene-C4 hydrolase) (EC 3.4.19.14) (CD antigen CD224) [Cleaved into: Glutathione hydrolase 1 heavy chain; Glutathione hydrolase 1 light chain] Rattus norvegicus (Rat) aging [GO:0007568]; amino acid metabolic process [GO:0006520]; cellular response to oxidative stress [GO:0034599]; cysteine biosynthetic process [GO:0019344]; fatty acid metabolic process [GO:0006631]; glutamate metabolic process [GO:0006536]; glutathione biosynthetic process [GO:0006750]; glutathione catabolic process [GO:0006751]; hepatoblast differentiation [GO:0061017]; hepatocyte differentiation [GO:0070365]; leukotriene D4 biosynthetic process [GO:1901750]; leukotriene metabolic process [GO:0006691]; liver regeneration [GO:0097421]; peptide modification [GO:0031179]; proteolysis [GO:0006508]; regulation of immune system process [GO:0002682]; regulation of inflammatory response [GO:0050727]; response to alcohol [GO:0097305]; response to estradiol [GO:0032355]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]; spermatogenesis [GO:0007283]; zymogen activation [GO:0031638] GO:0000048; GO:0002682; GO:0002951; GO:0005615; GO:0005886; GO:0006508; GO:0006520; GO:0006536; GO:0006631; GO:0006691; GO:0006750; GO:0006751; GO:0007283; GO:0007568; GO:0016755; GO:0019344; GO:0031179; GO:0031638; GO:0031982; GO:0032355; GO:0032496; GO:0034599; GO:0034612; GO:0036374; GO:0050727; GO:0061017; GO:0070365; GO:0097305; GO:0097421; GO:0102953; GO:0103068; GO:1901750 13976 XM_044327597.1 625 426 414 497 570 Q27HK4 2.62e-78 Metaxin-1 (Mitochondrial outer membrane import complex protein 1) Sus scrofa (Pig) mitochondrion organization [GO:0007005]; protein transport [GO:0015031] GO:0001401; GO:0005737; GO:0007005; GO:0015031 13977 XM_029355406.2 0 0 11 0 0 Q05793 0 Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG) [Cleaved into: Endorepellin; LG3 peptide] Mus musculus (Mouse) angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; brain development [GO:0007420]; cardiac muscle tissue development [GO:0048738]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; chondrocyte differentiation [GO:0002062]; embryonic skeletal system morphogenesis [GO:0048704]; endochondral ossification [GO:0001958]; extracellular matrix organization [GO:0030198]; negative regulation of amyloid fibril formation [GO:1905907]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell death [GO:0060548]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of endothelial cell proliferation [GO:0001938]; protein localization [GO:0008104]; receptor-mediated endocytosis [GO:0006898]; smoothened signaling pathway [GO:0007224]; tissue development [GO:0009888] GO:0001525; GO:0001938; GO:0001958; GO:0002020; GO:0002062; GO:0005509; GO:0005576; GO:0005604; GO:0005796; GO:0006898; GO:0007162; GO:0007224; GO:0007420; GO:0008022; GO:0008104; GO:0008285; GO:0009887; GO:0009888; GO:0030198; GO:0031012; GO:0048704; GO:0048738; GO:0060351; GO:0060548; GO:0062023; GO:0070052; GO:1905907 13978 XM_029355406.2 0 0 11 0 0 Q05793 0 Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG) [Cleaved into: Endorepellin; LG3 peptide] Mus musculus (Mouse) angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; brain development [GO:0007420]; cardiac muscle tissue development [GO:0048738]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; chondrocyte differentiation [GO:0002062]; embryonic skeletal system morphogenesis [GO:0048704]; endochondral ossification [GO:0001958]; extracellular matrix organization [GO:0030198]; negative regulation of amyloid fibril formation [GO:1905907]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell death [GO:0060548]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of endothelial cell proliferation [GO:0001938]; protein localization [GO:0008104]; receptor-mediated endocytosis [GO:0006898]; smoothened signaling pathway [GO:0007224]; tissue development [GO:0009888] GO:0001525; GO:0001938; GO:0001958; GO:0002020; GO:0002062; GO:0005509; GO:0005576; GO:0005604; GO:0005796; GO:0006898; GO:0007162; GO:0007224; GO:0007420; GO:0008022; GO:0008104; GO:0008285; GO:0009887; GO:0009888; GO:0030198; GO:0031012; GO:0048704; GO:0048738; GO:0060351; GO:0060548; GO:0062023; GO:0070052; GO:1905907 13979 XM_029355406.2 0 0 11 0 0 Q05793 0 Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG) [Cleaved into: Endorepellin; LG3 peptide] Mus musculus (Mouse) angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; brain development [GO:0007420]; cardiac muscle tissue development [GO:0048738]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; chondrocyte differentiation [GO:0002062]; embryonic skeletal system morphogenesis [GO:0048704]; endochondral ossification [GO:0001958]; extracellular matrix organization [GO:0030198]; negative regulation of amyloid fibril formation [GO:1905907]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell death [GO:0060548]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of endothelial cell proliferation [GO:0001938]; protein localization [GO:0008104]; receptor-mediated endocytosis [GO:0006898]; smoothened signaling pathway [GO:0007224]; tissue development [GO:0009888] GO:0001525; GO:0001938; GO:0001958; GO:0002020; GO:0002062; GO:0005509; GO:0005576; GO:0005604; GO:0005796; GO:0006898; GO:0007162; GO:0007224; GO:0007420; GO:0008022; GO:0008104; GO:0008285; GO:0009887; GO:0009888; GO:0030198; GO:0031012; GO:0048704; GO:0048738; GO:0060351; GO:0060548; GO:0062023; GO:0070052; GO:1905907 13980 XM_029355406.2 0 0 11 0 0 Q05793 7.18e-128 Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG) [Cleaved into: Endorepellin; LG3 peptide] Mus musculus (Mouse) angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; brain development [GO:0007420]; cardiac muscle tissue development [GO:0048738]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; chondrocyte differentiation [GO:0002062]; embryonic skeletal system morphogenesis [GO:0048704]; endochondral ossification [GO:0001958]; extracellular matrix organization [GO:0030198]; negative regulation of amyloid fibril formation [GO:1905907]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell death [GO:0060548]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of endothelial cell proliferation [GO:0001938]; protein localization [GO:0008104]; receptor-mediated endocytosis [GO:0006898]; smoothened signaling pathway [GO:0007224]; tissue development [GO:0009888] GO:0001525; GO:0001938; GO:0001958; GO:0002020; GO:0002062; GO:0005509; GO:0005576; GO:0005604; GO:0005796; GO:0006898; GO:0007162; GO:0007224; GO:0007420; GO:0008022; GO:0008104; GO:0008285; GO:0009887; GO:0009888; GO:0030198; GO:0031012; GO:0048704; GO:0048738; GO:0060351; GO:0060548; GO:0062023; GO:0070052; GO:1905907 13981 XM_029355406.2 0 0 11 0 0 Q05793 9.06e-60 Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG) [Cleaved into: Endorepellin; LG3 peptide] Mus musculus (Mouse) angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; brain development [GO:0007420]; cardiac muscle tissue development [GO:0048738]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; chondrocyte differentiation [GO:0002062]; embryonic skeletal system morphogenesis [GO:0048704]; endochondral ossification [GO:0001958]; extracellular matrix organization [GO:0030198]; negative regulation of amyloid fibril formation [GO:1905907]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell death [GO:0060548]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of endothelial cell proliferation [GO:0001938]; protein localization [GO:0008104]; receptor-mediated endocytosis [GO:0006898]; smoothened signaling pathway [GO:0007224]; tissue development [GO:0009888] GO:0001525; GO:0001938; GO:0001958; GO:0002020; GO:0002062; GO:0005509; GO:0005576; GO:0005604; GO:0005796; GO:0006898; GO:0007162; GO:0007224; GO:0007420; GO:0008022; GO:0008104; GO:0008285; GO:0009887; GO:0009888; GO:0030198; GO:0031012; GO:0048704; GO:0048738; GO:0060351; GO:0060548; GO:0062023; GO:0070052; GO:1905907 13982 XM_029355406.2 0 0 11 0 0 Q05793 4.02e-51 Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG) [Cleaved into: Endorepellin; LG3 peptide] Mus musculus (Mouse) angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; brain development [GO:0007420]; cardiac muscle tissue development [GO:0048738]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; chondrocyte differentiation [GO:0002062]; embryonic skeletal system morphogenesis [GO:0048704]; endochondral ossification [GO:0001958]; extracellular matrix organization [GO:0030198]; negative regulation of amyloid fibril formation [GO:1905907]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell death [GO:0060548]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of endothelial cell proliferation [GO:0001938]; protein localization [GO:0008104]; receptor-mediated endocytosis [GO:0006898]; smoothened signaling pathway [GO:0007224]; tissue development [GO:0009888] GO:0001525; GO:0001938; GO:0001958; GO:0002020; GO:0002062; GO:0005509; GO:0005576; GO:0005604; GO:0005796; GO:0006898; GO:0007162; GO:0007224; GO:0007420; GO:0008022; GO:0008104; GO:0008285; GO:0009887; GO:0009888; GO:0030198; GO:0031012; GO:0048704; GO:0048738; GO:0060351; GO:0060548; GO:0062023; GO:0070052; GO:1905907 13983 XM_029355406.2 0 0 11 0 0 Q05793 7.09e-43 Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG) [Cleaved into: Endorepellin; LG3 peptide] Mus musculus (Mouse) angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; brain development [GO:0007420]; cardiac muscle tissue development [GO:0048738]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; chondrocyte differentiation [GO:0002062]; embryonic skeletal system morphogenesis [GO:0048704]; endochondral ossification [GO:0001958]; extracellular matrix organization [GO:0030198]; negative regulation of amyloid fibril formation [GO:1905907]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell death [GO:0060548]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of endothelial cell proliferation [GO:0001938]; protein localization [GO:0008104]; receptor-mediated endocytosis [GO:0006898]; smoothened signaling pathway [GO:0007224]; tissue development [GO:0009888] GO:0001525; GO:0001938; GO:0001958; GO:0002020; GO:0002062; GO:0005509; GO:0005576; GO:0005604; GO:0005796; GO:0006898; GO:0007162; GO:0007224; GO:0007420; GO:0008022; GO:0008104; GO:0008285; GO:0009887; GO:0009888; GO:0030198; GO:0031012; GO:0048704; GO:0048738; GO:0060351; GO:0060548; GO:0062023; GO:0070052; GO:1905907 13984 XM_029355406.2 0 0 11 0 0 Q05793 7.09e-43 Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG) [Cleaved into: Endorepellin; LG3 peptide] Mus musculus (Mouse) angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; brain development [GO:0007420]; cardiac muscle tissue development [GO:0048738]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; chondrocyte differentiation [GO:0002062]; embryonic skeletal system morphogenesis [GO:0048704]; endochondral ossification [GO:0001958]; extracellular matrix organization [GO:0030198]; negative regulation of amyloid fibril formation [GO:1905907]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell death [GO:0060548]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of endothelial cell proliferation [GO:0001938]; protein localization [GO:0008104]; receptor-mediated endocytosis [GO:0006898]; smoothened signaling pathway [GO:0007224]; tissue development [GO:0009888] GO:0001525; GO:0001938; GO:0001958; GO:0002020; GO:0002062; GO:0005509; GO:0005576; GO:0005604; GO:0005796; GO:0006898; GO:0007162; GO:0007224; GO:0007420; GO:0008022; GO:0008104; GO:0008285; GO:0009887; GO:0009888; GO:0030198; GO:0031012; GO:0048704; GO:0048738; GO:0060351; GO:0060548; GO:0062023; GO:0070052; GO:1905907 13985 XM_029355406.2 0 0 11 0 0 Q05793 5.06e-33 Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG) [Cleaved into: Endorepellin; LG3 peptide] Mus musculus (Mouse) angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; brain development [GO:0007420]; cardiac muscle tissue development [GO:0048738]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; chondrocyte differentiation [GO:0002062]; embryonic skeletal system morphogenesis [GO:0048704]; endochondral ossification [GO:0001958]; extracellular matrix organization [GO:0030198]; negative regulation of amyloid fibril formation [GO:1905907]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell death [GO:0060548]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of endothelial cell proliferation [GO:0001938]; protein localization [GO:0008104]; receptor-mediated endocytosis [GO:0006898]; smoothened signaling pathway [GO:0007224]; tissue development [GO:0009888] GO:0001525; GO:0001938; GO:0001958; GO:0002020; GO:0002062; GO:0005509; GO:0005576; GO:0005604; GO:0005796; GO:0006898; GO:0007162; GO:0007224; GO:0007420; GO:0008022; GO:0008104; GO:0008285; GO:0009887; GO:0009888; GO:0030198; GO:0031012; GO:0048704; GO:0048738; GO:0060351; GO:0060548; GO:0062023; GO:0070052; GO:1905907 13986 XM_044318272.1 452 918 255 726 558 NA NA NA NA NA NA 13987 XM_029330809.2 1321 1207 730 1318 483 NA NA NA NA NA NA 13988 XM_029336698.2 31 9 24 27 56 NA NA NA NA NA NA 13989 XM_029357611.2 775 1403 864 1140 704 NA NA NA NA NA NA 13990 XM_044310504.1 0 6 7 4 33 Q96PD2 2.13e-23 Discoidin, CUB and LCCL domain-containing protein 2 (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1) (Endothelial and smooth muscle cell-derived neuropilin-like protein) Homo sapiens (Human) intracellular receptor signaling pathway [GO:0030522]; negative regulation of cell growth [GO:0030308]; wound healing [GO:0042060] GO:0005886; GO:0009986; GO:0030308; GO:0030522; GO:0038023; GO:0042060 13991 XM_044311753.1 0 0 6 8 0 NA NA NA NA NA NA 13992 XM_044323148.1 32 75 7 4 39 Q96IR2 0 Zinc finger protein 845 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 13993 XM_044323148.1 32 75 7 4 39 Q96IR2 0 Zinc finger protein 845 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 13994 XM_044323148.1 32 75 7 4 39 Q96IR2 0 Zinc finger protein 845 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 13995 XM_044323148.1 32 75 7 4 39 Q96IR2 6.77e-147 Zinc finger protein 845 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 13996 XM_044323148.1 32 75 7 4 39 Q96IR2 1.12e-137 Zinc finger protein 845 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 13997 XM_044323148.1 32 75 7 4 39 Q96IR2 3.65e-100 Zinc finger protein 845 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 13998 XM_044316535.1 40 2 2 0 14 Q13114 2.4e-65 TNF receptor-associated factor 3 (EC 2.3.2.27) (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein 1) (LAP1) (RING-type E3 ubiquitin transferase TRAF3) Homo sapiens (Human) apoptotic process [GO:0006915]; defense response to virus [GO:0051607]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of JNK cascade [GO:0046330]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of cytokine production [GO:0001817]; regulation of defense response to virus [GO:0050688]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of interferon-beta production [GO:0032648]; regulation of proteolysis [GO:0030162]; signal transduction [GO:0007165]; Toll signaling pathway [GO:0008063]; toll-like receptor signaling pathway [GO:0002224]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; type I interferon-mediated signaling pathway [GO:0060337] GO:0000151; GO:0001817; GO:0002224; GO:0004842; GO:0005164; GO:0005739; GO:0005768; GO:0005829; GO:0006915; GO:0007165; GO:0008063; GO:0008270; GO:0009898; GO:0019901; GO:0019903; GO:0030162; GO:0031625; GO:0031996; GO:0032088; GO:0032648; GO:0033209; GO:0035631; GO:0035666; GO:0042802; GO:0042981; GO:0043122; GO:0046330; GO:0050688; GO:0051607; GO:0060337; GO:0070534; GO:1902554 13999 XM_044310168.1 16 12 40 16 16 NA NA NA NA NA NA 14000 XM_044318009.1 25 0 0 5 0 NA NA NA NA NA NA 14001 XR_006392582.1 111 1 282 6 1 NA NA NA NA NA NA 14002 XM_044321612.1 1396 584 802 343 958 Q288C4 3.65e-37 NACHT, LRR and PYD domains-containing protein 9 Bos taurus (Bovine) inflammatory response [GO:0006954]; innate immune response [GO:0045087] GO:0005524; GO:0006954; GO:0045087; GO:0061702 14003 XM_029347521.2 680 374 437 402 661 NA NA NA NA NA NA 14004 XR_006392927.1 41 2 25 5 151 NA NA NA NA NA NA 14005 XM_029330683.2 8006 8322 5456 7065 3953 Q641G7 1.84e-106 Actin-related protein 2/3 complex subunit 4 Xenopus laevis (African clawed frog) actin filament polymerization [GO:0030041]; Arp2/3 complex-mediated actin nucleation [GO:0034314] GO:0003779; GO:0005634; GO:0005737; GO:0005885; GO:0030041; GO:0034314; GO:0035861; GO:0042995 14006 XM_044314078.1 16 0 7 0 0 NA NA NA NA NA NA 14007 XR_006397390.1 35 75 43 68 43 Q8R431 8.96e-58 Monoglyceride lipase (MGL) (EC 3.1.1.23) (Monoacylglycerol lipase) (MAGL) Rattus norvegicus (Rat) acylglycerol catabolic process [GO:0046464]; arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; long-term synaptic depression [GO:0060292]; monoacylglycerol catabolic process [GO:0052651]; positive regulation of vasoconstriction [GO:0045907]; regulation of axon extension [GO:0030516]; regulation of endocannabinoid signaling pathway [GO:2000124]; regulation of inflammatory response [GO:0050727]; regulation of sensory perception of pain [GO:0051930]; regulation of signal transduction [GO:0009966]; triglyceride catabolic process [GO:0019433] GO:0005811; GO:0005829; GO:0006633; GO:0009966; GO:0016020; GO:0016298; GO:0016787; GO:0019369; GO:0019433; GO:0019898; GO:0030424; GO:0030516; GO:0042803; GO:0043196; GO:0045202; GO:0045907; GO:0046464; GO:0047372; GO:0050727; GO:0051930; GO:0052651; GO:0060292; GO:2000124 14008 XR_006397390.1 35 75 43 68 43 Q8R431 8.96e-58 Monoglyceride lipase (MGL) (EC 3.1.1.23) (Monoacylglycerol lipase) (MAGL) Rattus norvegicus (Rat) acylglycerol catabolic process [GO:0046464]; arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; long-term synaptic depression [GO:0060292]; monoacylglycerol catabolic process [GO:0052651]; positive regulation of vasoconstriction [GO:0045907]; regulation of axon extension [GO:0030516]; regulation of endocannabinoid signaling pathway [GO:2000124]; regulation of inflammatory response [GO:0050727]; regulation of sensory perception of pain [GO:0051930]; regulation of signal transduction [GO:0009966]; triglyceride catabolic process [GO:0019433] GO:0005811; GO:0005829; GO:0006633; GO:0009966; GO:0016020; GO:0016298; GO:0016787; GO:0019369; GO:0019433; GO:0019898; GO:0030424; GO:0030516; GO:0042803; GO:0043196; GO:0045202; GO:0045907; GO:0046464; GO:0047372; GO:0050727; GO:0051930; GO:0052651; GO:0060292; GO:2000124 14009 XM_044327914.1 0 0 0 0 7 NA NA NA NA NA NA 14010 XM_029338366.2 0 84 39 0 67 Q9NQG7 5.72e-30 BLOC-3 complex member HPS4 (Hermansky-Pudlak syndrome 4 protein) (Light-ear protein homolog) Homo sapiens (Human) blood coagulation [GO:0007596]; hemostasis [GO:0007599]; intracellular transport [GO:0046907]; lysosome organization [GO:0007040]; melanocyte differentiation [GO:0030318]; melanosome assembly [GO:1903232]; platelet dense granule organization [GO:0060155]; positive regulation of eye pigmentation [GO:0048075]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein stabilization [GO:0050821]; protein targeting [GO:0006605]; vesicle-mediated transport [GO:0016192] GO:0005085; GO:0005737; GO:0005764; GO:0005765; GO:0005829; GO:0006605; GO:0007040; GO:0007596; GO:0007599; GO:0016020; GO:0016192; GO:0030318; GO:0031085; GO:0031267; GO:0031410; GO:0042470; GO:0042803; GO:0042827; GO:0046907; GO:0046983; GO:0048075; GO:0050821; GO:0060155; GO:1903232; GO:1903955 14011 XR_003827301.1 0 12 2 0 3 NA NA NA NA NA NA 14012 XM_029344125.2 1147 950 766 951 520 Q9QYU4 2.21e-94 Ketimine reductase mu-crystallin (EC 1.5.1.25) (CDK108) (NADP-regulated thyroid-hormone-binding protein) Rattus norvegicus (Rat) mitochondrial transport [GO:0006839]; negative regulation of transcription by RNA polymerase II [GO:0000122]; response to hormone [GO:0009725]; response to vitamin D [GO:0033280]; sensory perception of sound [GO:0007605]; thyroid hormone metabolic process [GO:0042403]; thyroid hormone transport [GO:0070327] GO:0000122; GO:0003714; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0006839; GO:0007605; GO:0009725; GO:0033280; GO:0042403; GO:0042562; GO:0042803; GO:0047127; GO:0050661; GO:0070324; GO:0070327 14013 XM_044320283.1 69 66 101 132 87 P10079 9.22e-107 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 14014 XM_044320283.1 69 66 101 132 87 P10079 1.39e-100 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 14015 XM_044320283.1 69 66 101 132 87 P10079 2.45e-40 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 14016 XM_044319972.1 89 83 165 208 103 P18665 7.3e-51 39S ribosomal protein L3, mitochondrial (L3mt) (MRP-L3) Rattus norvegicus (Rat) translation [GO:0006412] GO:0003735; GO:0005739; GO:0005762; GO:0006412 14017 XR_006396554.1 542 206 187 252 297 Q61382 5.6e-46 TNF receptor-associated factor 4 (EC 2.3.2.27) (Cysteine-rich motif associated to RING and Traf domains protein 1) Mus musculus (Mouse) activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; innate immune response [GO:0045087]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein kinase activity [GO:0045860]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; respiratory gaseous exchange by respiratory system [GO:0007585]; respiratory tube development [GO:0030323] GO:0001650; GO:0005164; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0005923; GO:0006915; GO:0007250; GO:0007585; GO:0008270; GO:0016740; GO:0019901; GO:0030323; GO:0031625; GO:0031996; GO:0042802; GO:0042981; GO:0043122; GO:0043161; GO:0045087; GO:0045860; GO:0046330; GO:0048471; GO:0050699 14018 XM_029342904.2 231 112 181 274 593 P21328 8.17e-27 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 14019 XM_029342904.2 231 112 181 274 593 P21328 8.17e-27 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 14020 XM_044321764.1 741 720 579 0 54 O57656 6.31e-117 Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic (GPD-C) (GPDH-C) (EC 1.1.1.8) Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate catabolic process [GO:0046168] GO:0005975; GO:0009331; GO:0042803; GO:0046168; GO:0047952; GO:0051287 14021 XM_044307967.1 0 0 2 0 13 NA NA NA NA NA NA 14022 XM_044318540.1 0 12 16 0 13 O75899 1.5e-88 Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51) (HG20) Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway [GO:0007186]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; neuron-glial cell signaling [GO:0150099]; synaptic transmission, GABAergic [GO:0051932] GO:0004888; GO:0004965; GO:0005737; GO:0005886; GO:0007186; GO:0007193; GO:0007194; GO:0007214; GO:0007268; GO:0038039; GO:0043005; GO:0045211; GO:0046982; GO:0051932; GO:0150099; GO:1902710; GO:1902712 14023 XM_029323552.2 0 0 0 6 0 NA NA NA NA NA NA 14024 XM_029358151.2 2631 1277 1417 2214 1896 Q8BYR2 0 Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) Mus musculus (Mouse) cell division [GO:0051301]; cytoplasmic sequestering of protein [GO:0051220]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; hippo signaling [GO:0035329]; hormone-mediated signaling pathway [GO:0009755]; inner cell mass cell fate commitment [GO:0001827]; inner cell mass cellular morphogenesis [GO:0001828]; intracellular signal transduction [GO:0035556]; keratinocyte differentiation [GO:0030216]; mammary gland epithelial cell differentiation [GO:0060644]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of protein localization to nucleus [GO:1900181]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of apoptotic process [GO:0043065]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; regulation of actin filament polymerization [GO:0030833]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of organ growth [GO:0046620]; regulation of protein-containing complex assembly [GO:0043254]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; regulation of ubiquitin-dependent protein catabolic process [GO:2000058]; sister chromatid segregation [GO:0000819] GO:0000082; GO:0000086; GO:0000287; GO:0000819; GO:0000922; GO:0001827; GO:0001828; GO:0004674; GO:0005524; GO:0005737; GO:0005815; GO:0006468; GO:0008104; GO:0009755; GO:0017015; GO:0018105; GO:0019901; GO:0030216; GO:0030331; GO:0030496; GO:0030833; GO:0033138; GO:0033146; GO:0035329; GO:0035556; GO:0043065; GO:0043254; GO:0045736; GO:0046620; GO:0051220; GO:0051301; GO:0060644; GO:0090090; GO:0106310; GO:1900181; GO:2000058 14025 XM_044310612.1 2031 1430 1360 889 630 P31836 3.56e-42 Neural cell adhesion molecule 1 (N-CAM-1) (NCAM-1) Bos taurus (Bovine) axon guidance [GO:0007411]; dendrite self-avoidance [GO:0070593]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005886; GO:0007156; GO:0007411; GO:0030424; GO:0070593; GO:0098632 14026 XM_029347181.2 1236 1536 1221 1275 1323 Q08DM7 2.16e-129 Neuronal-specific septin-3 Bos taurus (Bovine) cytoskeleton-dependent cytokinesis [GO:0061640] GO:0003924; GO:0005525; GO:0005940; GO:0015630; GO:0031105; GO:0032153; GO:0043005; GO:0060090; GO:0061640; GO:0098793; GO:0099569 14027 XM_029326060.2 0 0 0 0 14 P47739 6.16e-139 Aldehyde dehydrogenase, dimeric NADP-preferring (EC 1.2.1.5) (Aldehyde dehydrogenase 4) (Aldehyde dehydrogenase family 3 member A1) (Dioxin-inducible aldehyde dehydrogenase 3) Mus musculus (Mouse) cellular aldehyde metabolic process [GO:0006081]; lipid metabolic process [GO:0006629]; positive regulation of cell population proliferation [GO:0008284]; response to cAMP [GO:0051591]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to organic cyclic compound [GO:0014070]; response to xenobiotic stimulus [GO:0009410] GO:0001666; GO:0004028; GO:0004029; GO:0005737; GO:0005783; GO:0005829; GO:0005886; GO:0006081; GO:0006629; GO:0008106; GO:0008284; GO:0009410; GO:0014070; GO:0016020; GO:0016620; GO:0018479; GO:0051384; GO:0051591 14028 XR_003824818.2 1 0 0 17 15 NA NA NA NA NA NA 14029 XM_029339945.2 3216 3046 1691 2714 2613 P58374 2.3e-59 60S ribosomal protein L30 Branchiostoma belcheri (Amphioxus) NA GO:0003723; GO:0003735; GO:0022625 14030 XR_006395556.1 8 0 0 2 4 Q9UBN7 1.29e-73 Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-) Homo sapiens (Human) aggresome assembly [GO:0070842]; autophagy [GO:0006914]; axonal transport of mitochondrion [GO:0019896]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to misfolded protein [GO:0071218]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to topologically incorrect protein [GO:0035967]; cilium assembly [GO:0060271]; cilium disassembly [GO:0061523]; collateral sprouting [GO:0048668]; dendritic spine morphogenesis [GO:0060997]; epigenetic regulation of gene expression [GO:0040029]; histone deacetylation [GO:0016575]; Hsp90 deacetylation [GO:0070846]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of protein-containing complex disassembly [GO:0043242]; negative regulation of proteolysis [GO:0045861]; negative regulation of transcription by RNA polymerase II [GO:0000122]; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:0061734]; peptidyl-lysine deacetylation [GO:0034983]; polyubiquitinated misfolded protein transport [GO:0070845]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of hydrogen peroxide-mediated programmed cell death [GO:1901300]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of tubulin deacetylation [GO:0090044]; protein deacetylation [GO:0006476]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; protein-containing complex disassembly [GO:0032984]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of autophagy [GO:0010506]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of establishment of protein localization [GO:0070201]; regulation of fat cell differentiation [GO:0045598]; regulation of macroautophagy [GO:0016241]; regulation of microtubule-based movement [GO:0060632]; regulation of protein stability [GO:0031647]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]; response to dexamethasone [GO:0071548]; response to growth factor [GO:0070848]; response to immobilization stress [GO:0035902]; response to misfolded protein [GO:0051788]; tubulin deacetylation [GO:0090042]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] GO:0000118; GO:0000122; GO:0000209; GO:0000978; GO:0001222; GO:0001975; GO:0003779; GO:0004407; GO:0005634; GO:0005654; GO:0005737; GO:0005771; GO:0005813; GO:0005829; GO:0005874; GO:0005875; GO:0005901; GO:0006476; GO:0006515; GO:0006886; GO:0006914; GO:0007026; GO:0008013; GO:0008017; GO:0008270; GO:0010506; GO:0010634; GO:0010727; GO:0016234; GO:0016235; GO:0016241; GO:0016575; GO:0019896; GO:0019899; GO:0030424; GO:0030425; GO:0031252; GO:0031333; GO:0031593; GO:0031625; GO:0031647; GO:0031648; GO:0032418; GO:0032984; GO:0033138; GO:0033558; GO:0034983; GO:0035902; GO:0035967; GO:0036064; GO:0040029; GO:0042826; GO:0042903; GO:0043014; GO:0043130; GO:0043162; GO:0043204; GO:0043242; GO:0045598; GO:0045861; GO:0045892; GO:0048156; GO:0048471; GO:0048487; GO:0048668; GO:0048843; GO:0050775; GO:0051354; GO:0051412; GO:0051787; GO:0051788; GO:0051879; GO:0051968; GO:0060271; GO:0060632; GO:0060765; GO:0060997; GO:0061523; GO:0061734; GO:0070201; GO:0070301; GO:0070840; GO:0070842; GO:0070845; GO:0070846; GO:0070848; GO:0071218; GO:0071374; GO:0071548; GO:0090042; GO:0090044; GO:1901300; GO:1901984; GO:1903146; GO:1903223; GO:1904056; GO:1904115; GO:2000273 14031 XR_006395556.1 8 0 0 2 4 Q9UBN7 1.03e-67 Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-) Homo sapiens (Human) aggresome assembly [GO:0070842]; autophagy [GO:0006914]; axonal transport of mitochondrion [GO:0019896]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to misfolded protein [GO:0071218]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to topologically incorrect protein [GO:0035967]; cilium assembly [GO:0060271]; cilium disassembly [GO:0061523]; collateral sprouting [GO:0048668]; dendritic spine morphogenesis [GO:0060997]; epigenetic regulation of gene expression [GO:0040029]; histone deacetylation [GO:0016575]; Hsp90 deacetylation [GO:0070846]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of protein-containing complex disassembly [GO:0043242]; negative regulation of proteolysis [GO:0045861]; negative regulation of transcription by RNA polymerase II [GO:0000122]; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:0061734]; peptidyl-lysine deacetylation [GO:0034983]; polyubiquitinated misfolded protein transport [GO:0070845]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of hydrogen peroxide-mediated programmed cell death [GO:1901300]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of tubulin deacetylation [GO:0090044]; protein deacetylation [GO:0006476]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; protein-containing complex disassembly [GO:0032984]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of autophagy [GO:0010506]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of establishment of protein localization [GO:0070201]; regulation of fat cell differentiation [GO:0045598]; regulation of macroautophagy [GO:0016241]; regulation of microtubule-based movement [GO:0060632]; regulation of protein stability [GO:0031647]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]; response to dexamethasone [GO:0071548]; response to growth factor [GO:0070848]; response to immobilization stress [GO:0035902]; response to misfolded protein [GO:0051788]; tubulin deacetylation [GO:0090042]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] GO:0000118; GO:0000122; GO:0000209; GO:0000978; GO:0001222; GO:0001975; GO:0003779; GO:0004407; GO:0005634; GO:0005654; GO:0005737; GO:0005771; GO:0005813; GO:0005829; GO:0005874; GO:0005875; GO:0005901; GO:0006476; GO:0006515; GO:0006886; GO:0006914; GO:0007026; GO:0008013; GO:0008017; GO:0008270; GO:0010506; GO:0010634; GO:0010727; GO:0016234; GO:0016235; GO:0016241; GO:0016575; GO:0019896; GO:0019899; GO:0030424; GO:0030425; GO:0031252; GO:0031333; GO:0031593; GO:0031625; GO:0031647; GO:0031648; GO:0032418; GO:0032984; GO:0033138; GO:0033558; GO:0034983; GO:0035902; GO:0035967; GO:0036064; GO:0040029; GO:0042826; GO:0042903; GO:0043014; GO:0043130; GO:0043162; GO:0043204; GO:0043242; GO:0045598; GO:0045861; GO:0045892; GO:0048156; GO:0048471; GO:0048487; GO:0048668; GO:0048843; GO:0050775; GO:0051354; GO:0051412; GO:0051787; GO:0051788; GO:0051879; GO:0051968; GO:0060271; GO:0060632; GO:0060765; GO:0060997; GO:0061523; GO:0061734; GO:0070201; GO:0070301; GO:0070840; GO:0070842; GO:0070845; GO:0070846; GO:0070848; GO:0071218; GO:0071374; GO:0071548; GO:0090042; GO:0090044; GO:1901300; GO:1901984; GO:1903146; GO:1903223; GO:1904056; GO:1904115; GO:2000273 14032 XM_044321454.1 10 11 48 42 130 O43900 5.18e-127 Prickle planar cell polarity protein 3 (LIM domain only protein 6) (LMO-6) (Prickle-like protein 3) (Pk3) (Triple LIM domain protein 6) Homo sapiens (Human) cell projection organization [GO:0030030] GO:0005739; GO:0005886; GO:0008270; GO:0030030 14033 XM_029330748.2 350 302 113 235 269 F1NPG5 1.17e-26 Centromere protein T (CENP-T) Gallus gallus (Chicken) cell division [GO:0051301]; chromosome segregation [GO:0007059]; kinetochore assembly [GO:0051382]; mitotic cell cycle [GO:0000278] GO:0000278; GO:0000776; GO:0003677; GO:0005634; GO:0007059; GO:0046982; GO:0051301; GO:0051382 14034 XM_044326461.1 513 401 447 442 244 NA NA NA NA NA NA 14035 XR_006396851.1 0 0 29 78 35 NA NA NA NA NA NA 14036 XM_044308898.1 27 70 79 86 250 P54763 1.08e-83 Ephrin type-B receptor 2 (EC 2.7.10.1) (Neural kinase) (Nuk receptor tyrosine kinase) (Tyrosine-protein kinase receptor EPH-3) (Tyrosine-protein kinase receptor SEK-3) [Cleaved into: EphB2/CTF1; EphB2/CTF2] Mus musculus (Mouse) angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; axonogenesis [GO:0007409]; B cell activation [GO:0042113]; camera-type eye morphogenesis [GO:0048593]; cell morphogenesis [GO:0000902]; cellular response to amyloid-beta [GO:1904646]; cellular response to lipopolysaccharide [GO:0071222]; central nervous system projection neuron axonogenesis [GO:0021952]; commissural neuron axon guidance [GO:0071679]; corpus callosum development [GO:0022038]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; ephrin receptor signaling pathway [GO:0048013]; hindbrain tangential cell migration [GO:0021934]; inner ear morphogenesis [GO:0042472]; learning [GO:0007612]; learning or memory [GO:0007611]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of NMDA glutamate receptor activity [GO:1904782]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; neuron projection retraction [GO:0106028]; optic nerve morphogenesis [GO:0021631]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphorylation [GO:0016310]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell migration [GO:0030335]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of gene expression [GO:0010628]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of kinase activity [GO:0033674]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of tumor necrosis factor production [GO:0032760]; postsynaptic membrane assembly [GO:0097104]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of behavioral fear response [GO:2000822]; regulation of blood coagulation [GO:0030193]; regulation of body fluid levels [GO:0050878]; regulation of filopodium assembly [GO:0051489]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of receptor signaling pathway via JAK-STAT [GO:0046425]; regulation of synapse assembly [GO:0051963]; regulation of T-helper 17 type immune response [GO:2000316]; retinal ganglion cell axon guidance [GO:0031290]; roof of mouth development [GO:0060021]; tight junction assembly [GO:0120192]; trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission [GO:0099557]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; urogenital system development [GO:0001655]; vesicle-mediated intercellular transport [GO:0110077] GO:0000902; GO:0001525; GO:0001540; GO:0001655; GO:0001933; GO:0002639; GO:0004713; GO:0004714; GO:0005003; GO:0005005; GO:0005102; GO:0005524; GO:0005654; GO:0005794; GO:0005886; GO:0006468; GO:0006469; GO:0007162; GO:0007169; GO:0007409; GO:0007411; GO:0007413; GO:0007611; GO:0007612; GO:0008046; GO:0009887; GO:0009986; GO:0010628; GO:0016310; GO:0018108; GO:0021631; GO:0021934; GO:0021952; GO:0022038; GO:0030193; GO:0030335; GO:0030424; GO:0030425; GO:0030890; GO:0031290; GO:0031915; GO:0032760; GO:0033674; GO:0038023; GO:0042113; GO:0042472; GO:0042734; GO:0042802; GO:0043005; GO:0043025; GO:0043197; GO:0043235; GO:0044877; GO:0045202; GO:0045211; GO:0046425; GO:0046580; GO:0048013; GO:0048168; GO:0048170; GO:0048593; GO:0050770; GO:0050771; GO:0050878; GO:0051489; GO:0051963; GO:0051965; GO:0060021; GO:0060996; GO:0060997; GO:0061003; GO:0070373; GO:0071222; GO:0071679; GO:0097104; GO:0098686; GO:0098794; GO:0098978; GO:0099557; GO:0106028; GO:0110077; GO:0120192; GO:1900016; GO:1900273; GO:1903078; GO:1904646; GO:1904782; GO:1904783; GO:2000010; GO:2000316; GO:2000822 14037 XM_044311910.1 1 19 2 2 18 Q9UR07 4.49e-22 Transposon Tf2-11 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 14038 XM_029335821.2 665 299 314 714 911 Q17QF0 0 Alanine--glyoxylate aminotransferase 2, mitochondrial (AGT 2) (EC 2.6.1.44) ((R)-3-amino-2-methylpropionate--pyruvate transaminase) (EC 2.6.1.40) (Beta-ALAAT II) (Beta-alanine-pyruvate aminotransferase) (D-AIBAT) Bos taurus (Bovine) glyoxylate catabolic process [GO:0009436]; L-alanine catabolic process, by transamination [GO:0019481] GO:0005739; GO:0008453; GO:0009436; GO:0019481; GO:0030170; GO:0047305 14039 XM_029323855.2 819 724 474 520 602 Q566X8 1.25e-33 Diencephalon/mesencephalon homeobox protein 1-B Danio rerio (Zebrafish) (Brachydanio rerio) midbrain development [GO:0030901]; regulation of cell cycle [GO:0051726]; regulation of mitotic cell cycle [GO:0007346]; regulation of neural retina development [GO:0061074]; regulation of neurogenesis [GO:0050767]; regulation of transcription by RNA polymerase II [GO:0006357]; retina development in camera-type eye [GO:0060041] GO:0000977; GO:0000981; GO:0005634; GO:0006357; GO:0007346; GO:0030901; GO:0050767; GO:0051726; GO:0060041; GO:0061074 14040 XM_029351014.2 52 0 32 126 22 Q5R9E1 6.91e-102 Hydroxymethylglutaryl-CoA lyase, mitochondrial (HL) (HMG-CoA lyase) (EC 4.1.3.4) (3-hydroxy-3-methylglutarate-CoA lyase) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) ketone body biosynthetic process [GO:0046951] GO:0004419; GO:0005759; GO:0005777; GO:0046872; GO:0046951 14041 XM_029351014.2 52 0 32 126 22 Q5R9E1 6.91e-102 Hydroxymethylglutaryl-CoA lyase, mitochondrial (HL) (HMG-CoA lyase) (EC 4.1.3.4) (3-hydroxy-3-methylglutarate-CoA lyase) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) ketone body biosynthetic process [GO:0046951] GO:0004419; GO:0005759; GO:0005777; GO:0046872; GO:0046951 14042 XM_029356324.2 329 172 184 360 316 Q80T91 0 Multiple epidermal growth factor-like domains protein 11 (Multiple EGF-like domains protein 11) Mus musculus (Mouse) homotypic cell-cell adhesion [GO:0034109]; retina layer formation [GO:0010842] GO:0010842; GO:0016323; GO:0034109 14043 XM_044313196.1 5 0 2 6 1 NA NA NA NA NA NA 14044 XM_044307770.1 12 1 5 11 161 NA NA NA NA NA NA 14045 XM_029335633.2 75 8 40 57 93 NA NA NA NA NA NA 14046 XM_029331242.2 603 121 280 513 1029 Q924D0 1.91e-97 Reticulon-4-interacting protein 1, mitochondrial (NOGO-interacting mitochondrial protein) Mus musculus (Mouse) nervous system development [GO:0007399]; regulation of dendrite development [GO:0050773] GO:0005739; GO:0005741; GO:0007399; GO:0008270; GO:0016491; GO:0050773 14047 XR_006397329.1 585 947 22 470 310 NA NA NA NA NA NA 14048 XM_029351070.2 0 46 0 30 0 Q9N126 3.5e-63 Retinol dehydrogenase 8 (EC 1.1.1.300) (Photoreceptor outer segment all-trans retinol dehydrogenase) Bos taurus (Bovine) estrogen biosynthetic process [GO:0006703]; response to stimulus [GO:0050896]; retinol metabolic process [GO:0042572]; visual perception [GO:0007601] GO:0004303; GO:0004745; GO:0005829; GO:0006703; GO:0007601; GO:0016491; GO:0042572; GO:0042622; GO:0050896; GO:0052650 14049 XM_044314884.1 43 159 147 113 91 NA NA NA NA NA NA 14050 XM_044312441.1 2 0 13 0 0 NA NA NA NA NA NA 14051 XR_003824891.2 229 393 313 449 199 NA NA NA NA NA NA 14052 XM_044313034.1 4 0 6 4 12 Q96AY4 8.05e-106 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14053 XM_044313034.1 4 0 6 4 12 Q96AY4 1e-104 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14054 XM_044313034.1 4 0 6 4 12 Q96AY4 6.9e-99 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14055 XM_044313034.1 4 0 6 4 12 Q96AY4 1.41e-94 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14056 XM_044313034.1 4 0 6 4 12 Q96AY4 4.89e-94 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14057 XM_044313034.1 4 0 6 4 12 Q96AY4 2.46e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14058 XR_006397762.1 474 388 428 1 65 NA NA NA NA NA NA 14059 XM_044322753.1 17 337 233 95 81 NA NA NA NA NA NA 14060 XM_044307882.1 0 0 6 9 12 NA NA NA NA NA NA 14061 XM_044325235.1 101 76 436 1544 1372 Q9R1D7 0 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) protein transport [GO:0015031]; regulation of ARF protein signal transduction [GO:0032012] GO:0005085; GO:0005793; GO:0005794; GO:0005811; GO:0008289; GO:0015031; GO:0016020; GO:0032012 14062 XM_044325235.1 101 76 436 1544 1372 Q9R1D7 1.96e-89 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) protein transport [GO:0015031]; regulation of ARF protein signal transduction [GO:0032012] GO:0005085; GO:0005793; GO:0005794; GO:0005811; GO:0008289; GO:0015031; GO:0016020; GO:0032012 14063 XR_006396378.1 25 0 0 59 97 NA NA NA NA NA NA 14064 XR_006397236.1 12 234 0 5 4 NA NA NA NA NA NA 14065 XM_044316927.1 1016 658 625 1416 999 P70428 0 Exostosin-2 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Multiple exostoses protein 2 homolog) Mus musculus (Mouse) cellular polysaccharide biosynthetic process [GO:0033692]; cellular response to fibroblast growth factor stimulus [GO:0044344]; chondrocyte differentiation [GO:0002062]; endochondral bone morphogenesis [GO:0060350]; fluid transport [GO:0042044]; gene expression [GO:0010467]; glycosaminoglycan biosynthetic process [GO:0006024]; heart contraction [GO:0060047]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0015014]; heparin biosynthetic process [GO:0030210]; mesoderm formation [GO:0001707]; multicellular organismal water homeostasis [GO:0050891]; ossification [GO:0001503]; protein N-linked glycosylation [GO:0006487]; regulation of blood pressure [GO:0008217]; sodium ion homeostasis [GO:0055078]; sulfation [GO:0051923]; vasodilation [GO:0042311] GO:0000139; GO:0001503; GO:0001707; GO:0002062; GO:0005783; GO:0005789; GO:0005794; GO:0006024; GO:0006487; GO:0008217; GO:0008375; GO:0010467; GO:0015012; GO:0015014; GO:0015020; GO:0016757; GO:0030210; GO:0033692; GO:0042044; GO:0042311; GO:0042328; GO:0042803; GO:0043541; GO:0044344; GO:0046872; GO:0046982; GO:0050508; GO:0050509; GO:0050891; GO:0051923; GO:0055078; GO:0060047; GO:0060350 14066 XM_029346119.2 62 72 24 53 8 Q60452 0 General transcription and DNA repair factor IIH helicase subunit XPD (TFIIH subunit XPD) (EC 3.6.4.12) (CXPD) (DNA excision repair protein ERCC-2) (DNA repair protein complementing XP-D cells) (Xeroderma pigmentosum group D-complementing protein) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) apoptotic process [GO:0006915]; chromosome segregation [GO:0007059]; hair cell differentiation [GO:0035315]; nucleotide-excision repair [GO:0006289]; regulation of mitotic cell cycle phase transition [GO:1901990]; response to oxidative stress [GO:0006979]; transcription by RNA polymerase II [GO:0006366]; transcription-coupled nucleotide-excision repair [GO:0006283] GO:0003677; GO:0005524; GO:0005634; GO:0005675; GO:0005737; GO:0005819; GO:0006283; GO:0006289; GO:0006366; GO:0006915; GO:0006979; GO:0007059; GO:0008022; GO:0016887; GO:0035315; GO:0043139; GO:0046872; GO:0047485; GO:0051539; GO:0070516; GO:0071817; GO:1901990 14067 XM_044318593.1 618 450 347 387 970 Q9D6Y9 0 1,4-alpha-glucan-branching enzyme (EC 2.4.1.18) (Brancher enzyme) (Glycogen-branching enzyme) Mus musculus (Mouse) carbohydrate metabolic process [GO:0005975]; glycogen biosynthetic process [GO:0005978]; negative regulation of neuron apoptotic process [GO:0043524] GO:0003844; GO:0004553; GO:0005737; GO:0005829; GO:0005975; GO:0005978; GO:0030246; GO:0043169; GO:0043524; GO:0102752 14068 XM_029350554.2 118 97 50 70 63 Q8BKW4 1.41e-117 rRNA N6-adenosine-methyltransferase ZCCHC4 (EC 2.1.1.-) (Zinc finger CCHC domain-containing protein 4) Mus musculus (Mouse) positive regulation of translation [GO:0045727]; rRNA methylation [GO:0031167] GO:0003676; GO:0005730; GO:0005737; GO:0008270; GO:0008988; GO:0031167; GO:0045727; GO:1904047 14069 XM_029351316.2 568 549 238 253 280 Q9QZ85 1.65e-39 Interferon-inducible GTPase 1 (EC 3.6.5.-) Mus musculus (Mouse) cellular response to interferon-beta [GO:0035458]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; regulation of autophagy [GO:0010506]; response to bacterium [GO:0009617] GO:0003924; GO:0005525; GO:0005737; GO:0005789; GO:0006952; GO:0009617; GO:0010506; GO:0019003; GO:0019221; GO:0020005; GO:0031965; GO:0032580; GO:0035458; GO:0042802; GO:0042832; GO:0045087; GO:0050829 14070 XR_006396830.1 25 52 29 51 46 NA NA NA NA NA NA 14071 XR_006396240.1 0 10 0 57 37 NA NA NA NA NA NA 14072 XM_044321570.1 391 168 127 241 181 A0A1D3PCM3 1.54e-128 Serine O-succinyltransferase (SST) (EC 2.3.1.-) Emericella nidulans (Aspergillus nidulans) cysteine biosynthetic process [GO:0019344] GO:0005739; GO:0016747; GO:0019344 14073 XM_044311927.1 14 0 34 13 47 NA NA NA NA NA NA 14074 XM_044312328.1 35 346 5 135 113 NA NA NA NA NA NA 14075 XM_044318864.1 2904 1949 1915 2793 2424 P97393 0 Rho GTPase-activating protein 5 (Rho-type GTPase-activating protein 5) (p190-B) Mus musculus (Mouse) cell migration [GO:0016477]; epithelial cell migration [GO:0010631]; mammary gland development [GO:0030879]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of mesenchymal cell proliferation [GO:0002053]; regulation of cell size [GO:0008361]; Rho protein signal transduction [GO:0007266] GO:0002053; GO:0003924; GO:0005096; GO:0005525; GO:0005783; GO:0005829; GO:0005886; GO:0007266; GO:0008361; GO:0010631; GO:0010634; GO:0016477; GO:0030879; GO:0042169 14076 XM_044318864.1 2904 1949 1915 2793 2424 P97393 1.82e-35 Rho GTPase-activating protein 5 (Rho-type GTPase-activating protein 5) (p190-B) Mus musculus (Mouse) cell migration [GO:0016477]; epithelial cell migration [GO:0010631]; mammary gland development [GO:0030879]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of mesenchymal cell proliferation [GO:0002053]; regulation of cell size [GO:0008361]; Rho protein signal transduction [GO:0007266] GO:0002053; GO:0003924; GO:0005096; GO:0005525; GO:0005783; GO:0005829; GO:0005886; GO:0007266; GO:0008361; GO:0010631; GO:0010634; GO:0016477; GO:0030879; GO:0042169 14077 XM_029335116.2 1901 1663 1034 1703 1750 Q5SRX1 5.11e-112 TOM1-like protein 2 (Target of Myb-like protein 2) Mus musculus (Mouse) negative regulation of mitotic nuclear division [GO:0045839]; protein transport [GO:0015031]; signal transduction [GO:0007165] GO:0005768; GO:0007165; GO:0015031; GO:0016020; GO:0019901; GO:0030276; GO:0035091; GO:0043130; GO:0045839 14078 XR_006396146.1 39 20 38 36 59 NA NA NA NA NA NA 14079 XM_044313310.1 58 0 60 10 266 NA NA NA NA NA NA 14080 XM_044327830.1 27 24 12 7 21 O60290 1.03e-24 Zinc finger protein 862 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006355; GO:0046872; GO:0046983 14081 XM_029329908.2 1998 1883 755 1424 1586 Q99JI4 0 26S proteasome non-ATPase regulatory subunit 6 (26S proteasome regulatory subunit RPN7) (26S proteasome regulatory subunit S10) (p42A) Mus musculus (Mouse) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] GO:0000502; GO:0005838; GO:0022624; GO:0043161 14082 XM_029351905.2 0 0 0 248 0 Q9H892 9.96e-65 Tetratricopeptide repeat protein 12 (TPR repeat protein 12) Homo sapiens (Human) axonemal dynein complex assembly [GO:0070286]; sperm axoneme assembly [GO:0007288] GO:0005737; GO:0005813; GO:0007288; GO:0070286 14083 XM_044327484.1 2687 606 291 2086 481 Q96DM1 1.2e-62 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 14084 XM_044319123.1 43 25 65 275 221 NA NA NA NA NA NA 14085 XR_006397301.1 7 16 60 158 60 NA NA NA NA NA NA 14086 XR_003827544.2 5 1 7 6 0 NA NA NA NA NA NA 14087 XM_029336010.2 180 137 142 181 141 Q01528 2.13e-23 Hemagglutinin/amebocyte aggregation factor (18K-LAF) Limulus polyphemus (Atlantic horseshoe crab) NA GO:0005576 14088 XM_044316741.1 17 0 12 0 7 NA NA NA NA NA NA 14089 XM_044316696.1 20 0 39 0 10 NA NA NA NA NA NA 14090 XM_044326094.1 0 0 0 0 18 NA NA NA NA NA NA 14091 XM_029346091.2 1897 924 527 1950 1724 NA NA NA NA NA NA 14092 XM_029336479.2 0 61 42 0 0 Q26486 5.69e-33 46 kDa FK506-binding nuclear protein (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Spodoptera frugiperda (Fall armyworm) NA GO:0003677; GO:0003755; GO:0005634 14093 XR_006397594.1 490 444 273 408 431 NA NA NA NA NA NA 14094 XM_029356500.2 0 144 301 73 333 P52275 0 Tubulin beta-2 chain (Beta-2-tubulin) Caenorhabditis elegans meiotic spindle organization [GO:0000212]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278] GO:0000212; GO:0000226; GO:0000278; GO:0003924; GO:0005200; GO:0005525; GO:0005737; GO:0005874; GO:0005876; GO:0045298; GO:0046872 14095 XR_006392675.1 3 0 0 1 66 NA NA NA NA NA NA 14096 XR_003824524.2 1102 510 319 694 1098 NA NA NA NA NA NA 14097 XM_044329120.1 0 0 80 220 39 NA NA NA NA NA NA 14098 XM_044313175.1 1924 1485 962 2409 2604 P50532 0 Structural maintenance of chromosomes protein 4 (SMC protein 4) (SMC-4) (Chromosome assembly protein XCAP-C) (Chromosome-associated protein C) Xenopus laevis (African clawed frog) cell division [GO:0051301]; mitotic chromosome condensation [GO:0007076] GO:0005524; GO:0005634; GO:0005694; GO:0005829; GO:0007076; GO:0016887; GO:0051301 14099 XM_029347576.2 539 782 1345 1457 917 Q9CQ61 1.07e-78 Protein unc-50 homolog (Periodontal ligament-specific protein 22) (PDLs22) Mus musculus (Mouse) protein localization to cell surface [GO:0034394] GO:0000139; GO:0003723; GO:0005637; GO:0005794; GO:0034394 14100 XM_029349193.2 1 14 1 9 6 NA NA NA NA NA NA 14101 XM_044309759.1 139 32 75 81 264 NA NA NA NA NA NA 14102 XM_044328011.1 0 165 111 207 0 B2RS91 3.58e-133 RNA polymerase I-specific transcription initiation factor RRN3 Mus musculus (Mouse) cytoplasm organization [GO:0007028]; DNA-templated transcription initiation [GO:0006352]; fibroblast proliferation [GO:0048144]; homeostasis of number of cells [GO:0048872]; in utero embryonic development [GO:0001701]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902254]; nucleolus organization [GO:0007000]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of neuron projection development [GO:0010976]; regulation of DNA-templated transcription initiation [GO:2000142]; ribosome biogenesis [GO:0042254]; transcription initiation at RNA polymerase I promoter [GO:0006361] GO:0001042; GO:0001164; GO:0001181; GO:0001701; GO:0005634; GO:0005730; GO:0006352; GO:0006361; GO:0007000; GO:0007028; GO:0010976; GO:0042254; GO:0045893; GO:0048144; GO:0048872; GO:0070063; GO:0072332; GO:1902254; GO:2000142 14103 XM_029358166.2 1059 8 0 0 0 O00628 1.27e-127 Peroxisomal targeting signal 2 receptor (PTS2 receptor) (Peroxin-7) Homo sapiens (Human) endochondral ossification [GO:0001958]; ether lipid biosynthetic process [GO:0008611]; fatty acid beta-oxidation [GO:0006635]; neuron migration [GO:0001764]; peroxisome organization [GO:0007031]; protein import into peroxisome matrix [GO:0016558] GO:0001764; GO:0001958; GO:0005053; GO:0005777; GO:0005778; GO:0005782; GO:0005829; GO:0006635; GO:0007031; GO:0008611; GO:0016558; GO:0019899; GO:0042803 14104 XM_029351521.2 1072 677 817 1358 1279 Q05BQ1 2.97e-44 Protein turtle homolog A (Dendrite arborization and synapse maturation protein 1) (Immunoglobulin superfamily member 9A) (IgSF9A) Mus musculus (Mouse) cell-cell adhesion [GO:0098609]; dendrite development [GO:0016358]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; regulation of synapse organization [GO:0050807] GO:0005886; GO:0007156; GO:0016358; GO:0030424; GO:0030425; GO:0050807; GO:0060077; GO:0098609; GO:0098632 14105 XM_029330082.2 1104 538 371 726 765 Q80TM9 2.35e-71 Nischarin (Imidazoline receptor 1) (I-1) (IR1) (Imidazoline receptor I-1-like protein) (Imidazoline-1 receptor) (I1R) Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; apoptotic process [GO:0006915]; glucose metabolic process [GO:0006006]; negative regulation of cell migration [GO:0030336]; norepinephrine secretion [GO:0048243]; Rac protein signal transduction [GO:0016601]; regulation of blood pressure [GO:0008217]; regulation of synaptic transmission, GABAergic [GO:0032228] GO:0005178; GO:0005654; GO:0005737; GO:0005769; GO:0005829; GO:0005886; GO:0006006; GO:0006915; GO:0008217; GO:0015630; GO:0016601; GO:0019901; GO:0030036; GO:0030336; GO:0032228; GO:0035091; GO:0042802; GO:0043231; GO:0045171; GO:0048243; GO:0055037 14106 XM_029330082.2 1104 538 371 726 765 Q80TM9 8.85e-24 Nischarin (Imidazoline receptor 1) (I-1) (IR1) (Imidazoline receptor I-1-like protein) (Imidazoline-1 receptor) (I1R) Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; apoptotic process [GO:0006915]; glucose metabolic process [GO:0006006]; negative regulation of cell migration [GO:0030336]; norepinephrine secretion [GO:0048243]; Rac protein signal transduction [GO:0016601]; regulation of blood pressure [GO:0008217]; regulation of synaptic transmission, GABAergic [GO:0032228] GO:0005178; GO:0005654; GO:0005737; GO:0005769; GO:0005829; GO:0005886; GO:0006006; GO:0006915; GO:0008217; GO:0015630; GO:0016601; GO:0019901; GO:0030036; GO:0030336; GO:0032228; GO:0035091; GO:0042802; GO:0043231; GO:0045171; GO:0048243; GO:0055037 14107 XM_044315700.1 812 478 547 857 878 NA NA NA NA NA NA 14108 XM_029334006.2 400 432 307 515 388 Q5R7P7 7.96e-59 Transcription initiation factor TFIID subunit 9B Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) DNA-templated transcription initiation [GO:0006352]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cell growth [GO:0030307]; protein stabilization [GO:0050821] GO:0000122; GO:0003677; GO:0005669; GO:0006352; GO:0030307; GO:0033276; GO:0043066; GO:0046982; GO:0050821 14109 XM_029333335.2 198 88 61 60 125 Q8TEB9 4.65e-64 Rhomboid-related protein 4 (RRP4) (EC 3.4.21.105) (Rhomboid domain-containing protein 1) (Rhomboid-like protein 4) Homo sapiens (Human) apoptotic process [GO:0006915]; cellular response to unfolded protein [GO:0034620]; cellular response to UV [GO:0034644]; ERAD pathway [GO:0036503]; membrane protein intracellular domain proteolysis [GO:0031293]; membrane protein proteolysis [GO:0033619]; membrane protein proteolysis involved in retrograde protein transport, ER to cytosol [GO:1904211]; negative regulation of apoptotic process [GO:0043066]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein processing [GO:0010954]; positive regulation of secretion [GO:0051047]; post-translational protein modification [GO:0043687]; spermatid differentiation [GO:0048515] GO:0004175; GO:0004252; GO:0005783; GO:0005789; GO:0006915; GO:0010954; GO:0031293; GO:0031966; GO:0033619; GO:0034620; GO:0034644; GO:0036503; GO:0043066; GO:0043687; GO:0044322; GO:0045732; GO:0048515; GO:0051047; GO:1904211 14110 XM_029355561.2 40 0 36 13 169 O42574 3.69e-29 Beta-1 adrenergic receptor (Beta-1 adrenoreceptor) (Beta-1 adrenoceptor) (x-BETA1AR) Xenopus laevis (African clawed frog) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; positive regulation of GTPase activity [GO:0043547]; positive regulation of heart contraction [GO:0045823] GO:0004940; GO:0005085; GO:0005769; GO:0005886; GO:0043547; GO:0045823; GO:0071880 14111 XR_006394506.1 82 37 28 123 89 NA NA NA NA NA NA 14112 XM_029327753.1 1539 20 800 60 160 NA NA NA NA NA NA 14113 XM_044310661.1 3 1 7 6 22 O00370 3.08e-22 LINE-1 retrotransposable element ORF2 protein (ORF2p) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)] Homo sapiens (Human) DNA recombination [GO:0006310]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; reverse transcription involved in RNA-mediated transposition [GO:0032199]; transposition, RNA-mediated [GO:0032197] GO:0003723; GO:0003964; GO:0006310; GO:0009036; GO:0032197; GO:0032199; GO:0046872; GO:0090305 14114 XM_044310754.1 0 0 0 0 9 NA NA NA NA NA NA 14115 XM_044315507.1 0 4 0 6 1 NA NA NA NA NA NA 14116 XR_006397753.1 678 351 446 419 1138 NA NA NA NA NA NA 14117 XR_006393608.1 145 70 56 54 194 NA NA NA NA NA NA 14118 XM_044311549.1 9 0 0 0 0 NA NA NA NA NA NA 14119 XM_044314595.1 150 78 60 115 140 Q5U374 7.53e-54 Kelch-like protein 12 Danio rerio (Zebrafish) (Brachydanio rerio) anterior/posterior pattern specification [GO:0009952]; convergent extension involved in axis elongation [GO:0060028]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; protein monoubiquitination [GO:0006513]; Wnt signaling pathway [GO:0016055] GO:0006513; GO:0006888; GO:0009952; GO:0014029; GO:0014032; GO:0016055; GO:0030127; GO:0030134; GO:0031463; GO:0048208; GO:0060028 14120 XR_006397101.1 21 1 22 0 48 NA NA NA NA NA NA 14121 XM_044327553.1 1994 223 836 168 3072 NA NA NA NA NA NA 14122 XM_044319677.1 78 0 0 0 77 Q69Z28 4.21e-159 A disintegrin and metalloproteinase with thrombospondin motifs 16 (ADAM-TS 16) (ADAM-TS16) (ADAMTS-16) (EC 3.4.24.-) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; extracellular matrix organization [GO:0030198]; male gamete generation [GO:0048232]; proteolysis [GO:0006508]; regulation of cilium assembly [GO:1902017]; regulation of systemic arterial blood pressure [GO:0003073] GO:0001658; GO:0003073; GO:0004222; GO:0005576; GO:0006508; GO:0030198; GO:0031012; GO:0046872; GO:0048232; GO:1902017 14123 XM_029343245.2 5031 3677 1840 3505 3186 P60924 2.7e-31 DAP3-binding cell death enhancer 1 (DAP3-binding cell death enhancer 1, long form) (DELE1(L)) (Death ligand signal enhancer) [Cleaved into: DAP3-binding cell death enhancer 1 short form (DELE1(S)) (S-DELE1)] Rattus norvegicus (Rat) extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; HRI-mediated signaling [GO:0140468]; integrated stress response signaling [GO:0140467]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281] GO:0005739; GO:0005743; GO:0005829; GO:0008625; GO:0043281; GO:0043539; GO:0140467; GO:0140468 14124 XM_044308488.1 306 248 66 123 84 O13148 1.03e-26 Ephrin type-A receptor 4a (EC 2.7.10.1) (EPH-like kinase 2) (Tyrosine-protein kinase receptor ZEK2) Danio rerio (Zebrafish) (Brachydanio rerio) anterior/posterior pattern specification [GO:0009952]; axon guidance [GO:0007411]; cell-cell recognition [GO:0009988]; forebrain development [GO:0030900]; negative regulation of axon extension [GO:0030517]; negative regulation of collateral sprouting of intact axon in response to injury [GO:0048685]; optic vesicle morphogenesis [GO:0003404]; positive regulation of kinase activity [GO:0033674]; regulation of myelination [GO:0031641]; rhombomere boundary formation [GO:0021654]; somite development [GO:0061053]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0003404; GO:0004714; GO:0005005; GO:0005524; GO:0005769; GO:0005886; GO:0007169; GO:0007411; GO:0009952; GO:0009988; GO:0021654; GO:0030517; GO:0030900; GO:0031641; GO:0033674; GO:0043005; GO:0043197; GO:0043235; GO:0048685; GO:0061053 14125 XM_029344031.2 12 6 0 2 8 NA NA NA NA NA NA 14126 XM_044327720.1 15 54 53 0 10 NA NA NA NA NA NA 14127 XM_029335922.2 86 101 107 114 141 Q2XWK0 7.74e-117 Synaptic vesicle 2-related protein (SV2-related protein) Xenopus laevis (African clawed frog) NA GO:0022857; GO:0030672 14128 XM_044321740.1 0 125 35 0 483 NA NA NA NA NA NA 14129 XM_044320600.1 2 0 0 0 18 NA NA NA NA NA NA 14130 XR_006394723.1 8 0 0 3 0 NA NA NA NA NA NA 14131 XM_044327693.1 11 11 0 0 14 NA NA NA NA NA NA 14132 XM_029338810.2 234 0 0 68 170 Q96QT6 4.08e-73 PHD finger protein 12 (PHD factor 1) (Pf1) Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0001222; GO:0003714; GO:0005634; GO:0005654; GO:0006357; GO:0016580; GO:0017053; GO:0035091; GO:0045892; GO:0046872; GO:0070822 14133 XM_029338810.2 234 0 0 68 170 Q96QT6 1.34e-48 PHD finger protein 12 (PHD factor 1) (Pf1) Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0001222; GO:0003714; GO:0005634; GO:0005654; GO:0006357; GO:0016580; GO:0017053; GO:0035091; GO:0045892; GO:0046872; GO:0070822 14134 XM_044317769.1 0 85 150 316 409 P67999 0 Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA) Rattus norvegicus (Rat) aging [GO:0007568]; apoptotic process [GO:0006915]; behavioral fear response [GO:0001662]; cell migration [GO:0016477]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to growth factor stimulus [GO:0071363]; cellular response to hormone stimulus [GO:0032870]; cellular response to insulin stimulus [GO:0032869]; cellular response to organic cyclic compound [GO:0071407]; cellular response to type II interferon [GO:0071346]; G1/S transition of mitotic cell cycle [GO:0000082]; germ cell development [GO:0007281]; long-chain fatty acid import into cell [GO:0044539]; long-term memory [GO:0007616]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of insulin receptor signaling pathway [GO:0046627]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of skeletal muscle tissue growth [GO:0048633]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of translation [GO:0045727]; positive regulation of translational initiation [GO:0045948]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; regulation of glucose import [GO:0046324]; response to amino acid [GO:0043200]; response to electrical stimulus involved in regulation of muscle adaptation [GO:0014878]; response to ethanol [GO:0045471]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to insulin [GO:0032868]; response to leucine [GO:0043201]; response to lipopolysaccharide [GO:0032496]; response to mechanical stimulus [GO:0009612]; response to nutrient [GO:0007584]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to testosterone [GO:0033574]; response to toxic substance [GO:0009636]; response to tumor necrosis factor [GO:0034612]; response to wounding [GO:0009611]; response to xenobiotic stimulus [GO:0009410]; skeletal muscle atrophy [GO:0014732]; skeletal muscle contraction [GO:0003009]; TOR signaling [GO:0031929] GO:0000082; GO:0001662; GO:0003009; GO:0004672; GO:0004674; GO:0004711; GO:0004712; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005741; GO:0005829; GO:0006468; GO:0006915; GO:0007281; GO:0007568; GO:0007584; GO:0007616; GO:0009408; GO:0009410; GO:0009611; GO:0009612; GO:0009636; GO:0009749; GO:0009986; GO:0010033; GO:0010243; GO:0014070; GO:0014732; GO:0014878; GO:0014911; GO:0016477; GO:0018105; GO:0030165; GO:0031667; GO:0031929; GO:0032496; GO:0032868; GO:0032869; GO:0032870; GO:0033574; GO:0033762; GO:0034612; GO:0042277; GO:0042802; GO:0043005; GO:0043066; GO:0043200; GO:0043201; GO:0043434; GO:0043491; GO:0044539; GO:0045202; GO:0045471; GO:0045727; GO:0045931; GO:0045948; GO:0046324; GO:0046627; GO:0048471; GO:0048633; GO:0048661; GO:0050804; GO:0051384; GO:0051721; GO:0071346; GO:0071363; GO:0071407; GO:0071549; GO:0098794; GO:0098978; GO:0106310; GO:2001237 14135 XM_029342429.2 0 1136 843 887 60 Q5AF03 1.37e-29 Glyoxalase 3 (EC 4.2.1.130) (Glutathione-independent glyoxalase) Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243] GO:0005737; GO:0019172; GO:0019243; GO:0030445; GO:0030446; GO:0062040 14136 XM_029355743.2 31 12 12 20 13 NA NA NA NA NA NA 14137 XM_044328955.1 0 4 18 14 82 NA NA NA NA NA NA 14138 XM_029334654.2 138 80 0 317 214 Q69Z28 9.78e-107 A disintegrin and metalloproteinase with thrombospondin motifs 16 (ADAM-TS 16) (ADAM-TS16) (ADAMTS-16) (EC 3.4.24.-) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; extracellular matrix organization [GO:0030198]; male gamete generation [GO:0048232]; proteolysis [GO:0006508]; regulation of cilium assembly [GO:1902017]; regulation of systemic arterial blood pressure [GO:0003073] GO:0001658; GO:0003073; GO:0004222; GO:0005576; GO:0006508; GO:0030198; GO:0031012; GO:0046872; GO:0048232; GO:1902017 14139 XM_029346698.2 6082 6294 3821 6381 4536 Q13873 6.09e-89 Bone morphogenetic protein receptor type-2 (BMP type-2 receptor) (BMPR-2) (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II) Homo sapiens (Human) anterior/posterior pattern specification [GO:0009952]; aortic valve development [GO:0003176]; artery development [GO:0060840]; atrial septum morphogenesis [GO:0060413]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; BMP signaling pathway [GO:0030509]; cellular response to BMP stimulus [GO:0071773]; cellular response to growth factor stimulus [GO:0071363]; cellular response to starvation [GO:0009267]; chondrocyte development [GO:0002063]; endocardial cushion development [GO:0003197]; endochondral bone morphogenesis [GO:0060350]; endothelial cell apoptotic process [GO:0072577]; endothelial cell proliferation [GO:0001935]; limb development [GO:0060173]; lung alveolus development [GO:0048286]; lymphangiogenesis [GO:0001946]; lymphatic endothelial cell differentiation [GO:0060836]; maternal placenta development [GO:0001893]; mesoderm formation [GO:0001707]; mitral valve morphogenesis [GO:0003183]; negative regulation of cell growth [GO:0030308]; negative regulation of cell proliferation involved in heart valve morphogenesis [GO:0003252]; negative regulation of chondrocyte proliferation [GO:1902731]; negative regulation of DNA biosynthetic process [GO:2000279]; negative regulation of muscle cell differentiation [GO:0051148]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of systemic arterial blood pressure [GO:0003085]; negative regulation of vasoconstriction [GO:0045906]; osteoblast differentiation [GO:0001649]; outflow tract morphogenesis [GO:0003151]; outflow tract septum morphogenesis [GO:0003148]; pharyngeal arch artery morphogenesis [GO:0061626]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cartilage development [GO:0061036]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of gene expression [GO:0010628]; positive regulation of ossification [GO:0045778]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein phosphorylation [GO:0006468]; proteoglycan biosynthetic process [GO:0030166]; pulmonary valve development [GO:0003177]; regulation of cell population proliferation [GO:0042127]; regulation of lung blood pressure [GO:0014916]; retina vasculature development in camera-type eye [GO:0061298]; semi-lunar valve development [GO:1905314]; transmembrane receptor protein serine/threonine kinase signaling pathway [GO:0007178]; tricuspid valve morphogenesis [GO:0003186]; venous blood vessel development [GO:0060841]; ventricular septum morphogenesis [GO:0060412] GO:0001568; GO:0001649; GO:0001707; GO:0001893; GO:0001935; GO:0001938; GO:0001946; GO:0001974; GO:0002063; GO:0003085; GO:0003148; GO:0003151; GO:0003176; GO:0003177; GO:0003183; GO:0003186; GO:0003197; GO:0003252; GO:0004674; GO:0005024; GO:0005524; GO:0005615; GO:0005654; GO:0005886; GO:0005905; GO:0005912; GO:0006468; GO:0007178; GO:0009267; GO:0009952; GO:0009986; GO:0010595; GO:0010628; GO:0010634; GO:0010862; GO:0014069; GO:0014916; GO:0016362; GO:0019211; GO:0030166; GO:0030308; GO:0030424; GO:0030425; GO:0030501; GO:0030509; GO:0030513; GO:0030546; GO:0036122; GO:0042127; GO:0043235; GO:0043539; GO:0044297; GO:0045296; GO:0045669; GO:0045778; GO:0045906; GO:0045944; GO:0046872; GO:0048286; GO:0048662; GO:0048842; GO:0051148; GO:0060173; GO:0060350; GO:0060391; GO:0060412; GO:0060413; GO:0060836; GO:0060840; GO:0060841; GO:0061036; GO:0061298; GO:0061626; GO:0071363; GO:0071773; GO:0072577; GO:0098821; GO:0140537; GO:1902731; GO:1905314; GO:1990782; GO:2000279 14140 XM_029344776.2 27 9 14 17 13 Q5SVZ6 5.06e-21 Zinc finger MYM-type protein 1 Homo sapiens (Human) NA GO:0005634; GO:0008270; GO:0046983 14141 XM_029344776.2 27 9 14 17 13 Q5SVZ6 5.06e-21 Zinc finger MYM-type protein 1 Homo sapiens (Human) NA GO:0005634; GO:0008270; GO:0046983 14142 XM_029333891.2 252 113 72 262 119 NA NA NA NA NA NA 14143 XM_044307013.1 87 72 59 114 128 Q96L93 2.69e-122 Kinesin-like protein KIF16B (Sorting nexin-23) Homo sapiens (Human) early endosome to late endosome transport [GO:0045022]; endoderm development [GO:0007492]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; formation of primary germ layer [GO:0001704]; Golgi to endosome transport [GO:0006895]; microtubule-based movement [GO:0007018]; receptor catabolic process [GO:0032801]; regulation of receptor recycling [GO:0001919] GO:0001704; GO:0001919; GO:0003777; GO:0005524; GO:0005547; GO:0005737; GO:0005768; GO:0005769; GO:0005819; GO:0005829; GO:0005871; GO:0005874; GO:0006895; GO:0007018; GO:0007173; GO:0007492; GO:0008017; GO:0008543; GO:0008574; GO:0016887; GO:0031901; GO:0032266; GO:0032801; GO:0043325; GO:0045022; GO:0080025 14144 XM_029332918.2 26 8 14 12 46 Q91175 1.07e-22 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (MAR1) Oryzias latipes (Japanese rice fish) (Japanese killifish) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of vasoconstriction [GO:0045907] GO:0001996; GO:0004930; GO:0004937; GO:0005886; GO:0007200; GO:0007204; GO:0007267; GO:0043410; GO:0045907; GO:0071880 14145 XM_029355412.2 50 41 27 12 34 NA NA NA NA NA NA 14146 XM_044320372.1 17 18 20 27 20 NA NA NA NA NA NA 14147 XM_044322183.1 956 1049 368 607 518 NA NA NA NA NA NA 14148 XM_044311315.1 63 0 10 0 9 NA NA NA NA NA NA 14149 XM_029328807.2 0 0 0 28 24 NA NA NA NA NA NA 14150 XM_029332829.2 3913 2749 2028 4952 5075 D3ZFD0 0 Unconventional myosin-XVIIIa Rattus norvegicus (Rat) actomyosin structure organization [GO:0031032]; asymmetric Golgi ribbon formation [GO:0090164]; cell migration [GO:0016477]; cellular response to type II interferon [GO:0071346]; Golgi organization [GO:0007030]; Golgi ribbon formation [GO:0090161]; Golgi vesicle budding [GO:0048194]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; negative regulation of apoptotic process [GO:0043066]; positive regulation of opsonization [GO:1903028]; positive regulation of protein secretion [GO:0050714]; regulation of macrophage activation [GO:0043030] GO:0000139; GO:0003774; GO:0005524; GO:0005802; GO:0005856; GO:0005903; GO:0007030; GO:0007249; GO:0016460; GO:0016477; GO:0031032; GO:0032982; GO:0042641; GO:0043030; GO:0043066; GO:0043531; GO:0045335; GO:0048194; GO:0050714; GO:0051015; GO:0071346; GO:0090161; GO:0090164; GO:1903028 14151 XR_003823827.2 59 32 44 26 119 NA NA NA NA NA NA 14152 XR_003826910.2 223 97 62 86 105 NA NA NA NA NA NA 14153 XM_044319692.1 217 189 275 122 559 Q3V050 1.43e-87 Multidrug and toxin extrusion protein 2 (MATE-2) (mMATE-2) (H(+)/organic cation antiporter kidney-specific) (Solute carrier family 47 member 2) Mus musculus (Mouse) organic cation transport [GO:0015695]; xenobiotic detoxification by transmembrane export across the plasma membrane [GO:1990961] GO:0005886; GO:0015101; GO:0015179; GO:0015297; GO:0015299; GO:0015695; GO:0016020; GO:0016323; GO:0016324; GO:0022857; GO:0042910; GO:0061459; GO:1990961 14154 XM_044313426.1 441 137 36 0 94 Q5JL96 5.26e-30 Probable E3 ubiquitin-protein ligase RZFP34 (EC 2.3.2.27) (OsRFP1) (RING zinc-finger protein 34) (OsRZFP34) Oryza sativa subsp. japonica (Rice) protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0005634; GO:0006511; GO:0008270; GO:0016567; GO:0061630 14155 XM_029355595.2 448 2003 1064 493 399 A7SPE8 1.29e-34 Biogenesis of lysosome-related organelles complex 1 subunit 5 (BLOC-1 subunit 5) (Protein Muted homolog) Nematostella vectensis (Starlet sea anemone) NA GO:0030133; GO:0031083 14156 XM_029343877.2 953 738 498 965 978 Q5THR3 8.35e-168 EF-hand calcium-binding domain-containing protein 6 (CAP-binding protein complex-interacting protein 1) (DJ-1-binding protein) (DJBP) Homo sapiens (Human) NA GO:0005509; GO:0005654; GO:0005737; GO:0005856; GO:0042995 14157 XR_003823646.2 47 35 10 50 8 NA NA NA NA NA NA 14158 XR_006395292.1 33 21 21 43 100 NA NA NA NA NA NA 14159 XM_029349924.2 2891 2823 1584 2848 3062 P54359 0 Septin-2 Drosophila melanogaster (Fruit fly) cellularization [GO:0007349]; cytoskeleton-dependent cytokinesis [GO:0061640]; growth of a germarium-derived egg chamber [GO:0007295]; imaginal disc development [GO:0007444]; regulation of cell cycle [GO:0051726] GO:0003924; GO:0005525; GO:0005819; GO:0005940; GO:0007295; GO:0007349; GO:0007444; GO:0015630; GO:0031105; GO:0032153; GO:0042803; GO:0051726; GO:0060090; GO:0061640 14160 XM_029356121.2 0 0 0 29 0 NA NA NA NA NA NA 14161 XM_044322026.1 26 11 21 43 21 P09487 5.33e-136 Alkaline phosphatase, tissue-nonspecific isozyme (AP-TNAP) (TNAP) (TNSALP) (EC 3.1.3.1) (Alkaline phosphatase liver/bone/kidney isozyme) (Phosphoamidase) (Phosphocreatine phosphatase) (EC 3.9.1.1) Bos taurus (Bovine) biomineral tissue development [GO:0031214]; bone mineralization [GO:0030282]; calcium ion homeostasis [GO:0055074]; cellular homeostasis [GO:0019725]; cellular response to organic cyclic compound [GO:0071407]; dephosphorylation [GO:0016311]; developmental process involved in reproduction [GO:0003006]; endochondral ossification [GO:0001958]; multicellular organism aging [GO:0010259]; phosphate ion homeostasis [GO:0055062]; positive regulation of cold-induced thermogenesis [GO:0120162]; pyridoxal phosphate metabolic process [GO:0042822]; response to antibiotic [GO:0046677]; response to sodium phosphate [GO:1904383]; response to vitamin B6 [GO:0034516]; response to vitamin D [GO:0033280] GO:0001958; GO:0003006; GO:0004035; GO:0004427; GO:0005509; GO:0005758; GO:0005886; GO:0010259; GO:0016311; GO:0016462; GO:0016887; GO:0019725; GO:0030282; GO:0031012; GO:0031214; GO:0031966; GO:0033280; GO:0033883; GO:0034516; GO:0042822; GO:0043262; GO:0046677; GO:0050187; GO:0052732; GO:0055062; GO:0055074; GO:0065010; GO:0071407; GO:0120162; GO:1904383 14162 XM_029353897.2 801 795 1074 1427 1472 NA NA NA NA NA NA 14163 XM_044316891.1 112 139 145 106 154 NA NA NA NA NA NA 14164 XM_029333857.2 440 519 338 476 434 Q6P8E9 4.03e-65 NHP2-like protein 1 (High mobility group-like nuclear protein 2 homolog 1) (U4/U6.U5 small nuclear ribonucleoprotein SNU13) (U4/U6.U5 tri-snRNP 15.5 kDa protein) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) mRNA splicing, via spliceosome [GO:0000398]; ribosome biogenesis [GO:0042254] GO:0000398; GO:0005634; GO:0005690; GO:0005730; GO:0030622; GO:0042254; GO:0046540; GO:0071005 14165 XM_044328893.1 24 0 0 15 8 NA NA NA NA NA NA 14166 XM_044308327.1 41 493 24 34 150 NA NA NA NA NA NA 14167 XM_044311702.1 8522 8815 1288 4460 11231 P10160 1.53e-69 Eukaryotic translation initiation factor 5A-1 (eIF-5A-1) (eIF-5A1) (Eukaryotic initiation factor 5A isoform 1) (eIF-5A) (eIF-4D) Oryctolagus cuniculus (Rabbit) positive regulation of translation [GO:0045727]; positive regulation of translational elongation [GO:0045901]; positive regulation of translational termination [GO:0045905] GO:0003723; GO:0003746; GO:0005634; GO:0005789; GO:0043022; GO:0045727; GO:0045901; GO:0045905 14168 XM_029335004.2 59 23 33 181 183 Q92626 5.79e-84 Peroxidasin homolog (EC 1.11.2.-) (Melanoma-associated antigen MG50) (Peroxidasin 1) (hsPxd01) (Vascular peroxidase 1) (p53-responsive gene 2 protein) [Cleaved into: PXDN active fragment] Homo sapiens (Human) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; immune response [GO:0006955]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005152; GO:0005201; GO:0005576; GO:0005604; GO:0005615; GO:0005783; GO:0006955; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070062; GO:0070207; GO:0070831; GO:0071711; GO:0140825 14169 XM_044327038.1 1 0 5 229 124 NA NA NA NA NA NA 14170 XM_029343339.2 13 6 16 6 31 NA NA NA NA NA NA 14171 XM_029355484.2 50 14 35 41 58 Q6ZTW0 6.46e-30 Tubulin polyglutamylase complex subunit 1 (PGs1) Homo sapiens (Human) adult behavior [GO:0030534]; chemical synaptic transmission [GO:0007268]; protein polyglutamylation [GO:0018095]; sperm axoneme assembly [GO:0007288]; vesicle localization [GO:0051648] GO:0005737; GO:0005813; GO:0005874; GO:0007268; GO:0007288; GO:0008017; GO:0018095; GO:0030424; GO:0030425; GO:0030534; GO:0031514; GO:0045202; GO:0051648; GO:0070740 14172 XM_029338462.2 127 87 73 79 118 Q9D995 7.3e-36 Cyclin N-terminal domain-containing protein 1 Mus musculus (Mouse) reciprocal meiotic recombination [GO:0007131]; regulation of meiotic cell cycle [GO:0051445]; spermatogenesis [GO:0007283] GO:0005634; GO:0005694; GO:0005737; GO:0007131; GO:0007283; GO:0035861; GO:0051445 14173 XR_006394782.1 22 4 9 7 0 NA NA NA NA NA NA 14174 XM_029323982.2 134 14 33 47 0 O55236 0 mRNA-capping enzyme (HCE) (MCE1) [Includes: mRNA 5'-triphosphate monophosphatase (EC 3.6.1.74) (mRNA 5'-phosphatase); mRNA guanylyltransferase (EC 2.7.7.50) (GTP--RNA guanylyltransferase) (GTase)] Mus musculus (Mouse) 7-methylguanosine mRNA capping [GO:0006370]; protein dephosphorylation [GO:0006470]; RNA processing [GO:0006396] GO:0004484; GO:0004651; GO:0005524; GO:0005525; GO:0005634; GO:0006370; GO:0006396; GO:0006470; GO:0008138; GO:0008192; GO:0050355; GO:0140818 14175 XM_029358205.2 418 438 327 463 442 NA NA NA NA NA NA 14176 XM_044318645.1 225 129 101 151 141 Q5T7P8 5.57e-53 Synaptotagmin-6 (Synaptotagmin VI) (SytVI) Homo sapiens (Human) acrosomal vesicle exocytosis [GO:0060478]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; vesicle-mediated transport [GO:0016192] GO:0000149; GO:0001786; GO:0005509; GO:0005829; GO:0005886; GO:0014059; GO:0016020; GO:0016192; GO:0017156; GO:0017158; GO:0019898; GO:0019905; GO:0030276; GO:0030672; GO:0042803; GO:0060478; GO:0070382; GO:0071277; GO:0097038 14177 XM_029340405.2 490 418 257 623 374 Q5ZKN1 2.14e-174 Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 9) Gallus gallus (Chicken) positive regulation of protein localization to chromatin [GO:0120187]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; protein phosphorylation [GO:0006468]; transcription by RNA polymerase II [GO:0006366] GO:0004674; GO:0004693; GO:0005524; GO:0005634; GO:0006366; GO:0006468; GO:0008353; GO:0016592; GO:0032968; GO:0045944; GO:0070691; GO:0106310; GO:0120187 14178 XM_029336990.2 122 90 20 84 59 NA NA NA NA NA NA 14179 XM_029329860.2 203 1 96 488 223 P20072 1.23e-70 Annexin A7 (Annexin VII) (Annexin-7) (Synexin) Bos taurus (Bovine) NA GO:0005509; GO:0005544; GO:0005634; GO:0005737; GO:0042584 14180 XM_029338573.2 0 8 0 0 13 NA NA NA NA NA NA 14181 XM_044312836.1 1433 1137 981 803 1397 Q6PD24 1.21e-162 Ankyrin repeat domain-containing protein 13D Mus musculus (Mouse) negative regulation of receptor internalization [GO:0002091] GO:0002091; GO:0005737; GO:0005770; GO:0005886; GO:0048471; GO:0140036 14182 XM_029336429.2 27 39 144 40 108 Q5ZHN3 0 WD repeat domain phosphoinositide-interacting protein 2 (WIPI-2) Gallus gallus (Chicken) autophagosome assembly [GO:0000045]; autophagy of mitochondrion [GO:0000422]; autophagy of nucleus [GO:0044804]; cellular response to starvation [GO:0009267]; protein lipidation [GO:0006497]; protein localization to phagophore assembly site [GO:0034497] GO:0000045; GO:0000422; GO:0005829; GO:0006497; GO:0009267; GO:0019898; GO:0032266; GO:0034045; GO:0034497; GO:0044804; GO:0080025 14183 XM_044307037.1 176 337 183 630 123 Q7RTR2 6.77e-74 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 14184 XM_044307037.1 176 337 183 630 123 Q7RTR2 7.48e-74 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 14185 XM_044307037.1 176 337 183 630 123 Q7RTR2 2.2e-72 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 14186 XM_044307037.1 176 337 183 630 123 Q7RTR2 2.51e-70 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 14187 XM_044307037.1 176 337 183 630 123 Q7RTR2 1.14e-68 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 14188 XM_044307037.1 176 337 183 630 123 Q7RTR2 7.26e-68 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 14189 XM_044307037.1 176 337 183 630 123 Q7RTR2 1.83e-65 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 14190 XM_044307037.1 176 337 183 630 123 Q7RTR2 2.87e-56 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 14191 XM_044307037.1 176 337 183 630 123 Q7RTR2 8.9e-49 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 14192 XM_029348263.2 1092 1037 420 1154 1288 Q6P877 1.55e-57 Proteasomal ubiquitin receptor ADRM1 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) proteasome assembly [GO:0043248] GO:0000502; GO:0005634; GO:0005737; GO:0043248; GO:0061133 14193 XM_029348263.2 1092 1037 420 1154 1288 Q6P877 1.42e-30 Proteasomal ubiquitin receptor ADRM1 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) proteasome assembly [GO:0043248] GO:0000502; GO:0005634; GO:0005737; GO:0043248; GO:0061133 14194 XM_044316407.1 772 957 281 504 1064 O60502 3.95e-24 Protein O-GlcNAcase (OGA) (EC 3.2.1.169) (Beta-N-acetylglucosaminidase) (Beta-N-acetylhexosaminidase) (Beta-hexosaminidase) (Meningioma-expressed antigen 5) (N-acetyl-beta-D-glucosaminidase) (N-acetyl-beta-glucosaminidase) (Nuclear cytoplasmic O-GlcNAcase and acetyltransferase) (NCOAT) Homo sapiens (Human) glycoprotein catabolic process [GO:0006516]; glycoprotein metabolic process [GO:0009100]; N-acetylglucosamine metabolic process [GO:0006044]; protein deglycosylation [GO:0006517]; protein O-linked glycosylation [GO:0006493] GO:0004415; GO:0005634; GO:0005829; GO:0006044; GO:0006493; GO:0006516; GO:0006517; GO:0009100; GO:0016020; GO:0016231; GO:0042802; GO:0102166; GO:0102167; GO:0102571 14195 XM_044307226.1 69 21 119 23 49 NA NA NA NA NA NA 14196 XM_044308979.1 800 419 371 763 1057 Q96AY4 9.85e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14197 XM_044308979.1 800 419 371 763 1057 Q96AY4 1.46e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14198 XM_044308979.1 800 419 371 763 1057 Q96AY4 2.08e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14199 XM_044308979.1 800 419 371 763 1057 Q96AY4 2.53e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14200 XM_044308979.1 800 419 371 763 1057 Q96AY4 1.13e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14201 XM_044308979.1 800 419 371 763 1057 Q96AY4 2.12e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14202 XM_044308979.1 800 419 371 763 1057 Q96AY4 2.51e-37 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14203 XM_044308979.1 800 419 371 763 1057 Q96AY4 2.31e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14204 XM_044308979.1 800 419 371 763 1057 Q96AY4 2.51e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14205 XM_044308979.1 800 419 371 763 1057 Q96AY4 1.22e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14206 XM_044308979.1 800 419 371 763 1057 Q96AY4 1.59e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14207 XM_044308979.1 800 419 371 763 1057 Q96AY4 1.87e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14208 XM_044308979.1 800 419 371 763 1057 Q96AY4 3.37e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14209 XM_044308979.1 800 419 371 763 1057 Q96AY4 5.08e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14210 XM_044320499.1 3300 848 1674 963 709 D3ZGB1 7.9e-33 Nuclear factor of activated T-cells 5 (NF-AT5) (T-cell transcription factor NFAT5) Rattus norvegicus (Rat) calcineurin-NFAT signaling cascade [GO:0033173]; cellular response to cytokine stimulus [GO:0071345]; cellular response to DNA damage stimulus [GO:0006974]; positive regulation of gene expression [GO:0010628]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R-loop processing [GO:0062176]; regulation of calcineurin-NFAT signaling cascade [GO:0070884]; regulation of transcription by RNA polymerase II [GO:0006357]; response to osmotic stress [GO:0006970] GO:0000978; GO:0000981; GO:0001228; GO:0003677; GO:0003682; GO:0005634; GO:0005654; GO:0005667; GO:0005694; GO:0005737; GO:0005829; GO:0006357; GO:0006970; GO:0006974; GO:0010628; GO:0033173; GO:0045944; GO:0062176; GO:0070884; GO:0071345; GO:1901224; GO:1904996; GO:1990837 14211 XM_044318393.1 19 18 30 10 16 NA NA NA NA NA NA 14212 XM_044312350.1 1 0 9 0 44 Q61830 2.77e-86 Macrophage mannose receptor 1 (MMR) (CD antigen CD206) Mus musculus (Mouse) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 14213 XM_044312350.1 1 0 9 0 44 Q61830 6e-85 Macrophage mannose receptor 1 (MMR) (CD antigen CD206) Mus musculus (Mouse) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 14214 XM_044312350.1 1 0 9 0 44 Q61830 6.58e-62 Macrophage mannose receptor 1 (MMR) (CD antigen CD206) Mus musculus (Mouse) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 14215 XM_044312350.1 1 0 9 0 44 Q61830 4.03e-38 Macrophage mannose receptor 1 (MMR) (CD antigen CD206) Mus musculus (Mouse) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 14216 XM_044324740.1 108 6 41 54 20 Q9UBM8 9.74e-25 Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C (EC 2.4.1.145) (N-acetylglucosaminyltransferase IV homolog) (hGnT-IV-H) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVc) (GlcNAc-T IVc) (GnT-IVc) (N-acetylglucosaminyltransferase IVc) (UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVc) Homo sapiens (Human) protein N-linked glycosylation [GO:0006487]; viral protein processing [GO:0019082] GO:0000139; GO:0006487; GO:0008375; GO:0008454; GO:0019082; GO:0046872 14217 XM_029352943.2 0 0 0 7 0 NA NA NA NA NA NA 14218 XM_029349309.2 257 127 95 12 250 NA NA NA NA NA NA 14219 XM_044326193.1 83 1 34 20 67 Q09575 2.05e-39 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 14220 XM_044309692.1 187 129 0 4 32 NA NA NA NA NA NA 14221 XM_044326272.1 0 0 0 0 10 O93530 5.59e-48 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN (Focus-forming activity 1) (FFA-1) (Werner syndrome protein homolog) [Includes: 3'-5' exonuclease (EC 3.1.-.-); ATP-dependent helicase (EC 3.6.4.12)] Xenopus laevis (African clawed frog) DNA metabolic process [GO:0006259]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260] GO:0000287; GO:0003677; GO:0005524; GO:0005654; GO:0005730; GO:0006259; GO:0006260; GO:0006281; GO:0006310; GO:0008408; GO:0016887; GO:0030145; GO:0043138 14222 XM_044312573.1 6 3 1 3 0 NA NA NA NA NA NA 14223 XR_006398103.1 80 38 16 22 63 NA NA NA NA NA NA 14224 XM_044311337.1 13 0 13 0 8 O75051 0 Plexin-A2 (Semaphorin receptor OCT) Homo sapiens (Human) centrosome localization [GO:0051642]; cerebellar granule cell precursor tangential migration [GO:0021935]; limb bud formation [GO:0060174]; negative regulation of cell adhesion [GO:0007162]; neural tube development [GO:0021915]; pharyngeal system development [GO:0060037]; positive regulation of axonogenesis [GO:0050772]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; somitogenesis [GO:0001756] GO:0001756; GO:0002116; GO:0005886; GO:0007162; GO:0008360; GO:0017154; GO:0021915; GO:0021935; GO:0030334; GO:0042802; GO:0043087; GO:0050772; GO:0051642; GO:0060037; GO:0060174; GO:0071526; GO:1902287 14225 XM_029344151.2 4548 5426 4541 3840 2216 P50408 3.25e-56 V-type proton ATPase subunit F (V-ATPase subunit F) (V-ATPase 14 kDa subunit) (Vacuolar proton pump subunit F) Rattus norvegicus (Rat) synaptic vesicle lumen acidification [GO:0097401] GO:0000221; GO:0016020; GO:0016471; GO:0030665; GO:0033176; GO:0046961; GO:0097401; GO:0098850; GO:1902495; GO:1904949 14226 XM_029355848.2 356 524 417 358 199 NA NA NA NA NA NA 14227 XM_029348659.2 54 33 47 27 57 E7FAM5 1.06e-81 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 14228 XR_003822952.2 92 484 66 100 148 Q8VXZ0 2.61e-43 Nudix hydrolase 20, chloroplastic (AtNUDT20) (EC 3.6.1.-) Arabidopsis thaliana (Mouse-ear cress) NA GO:0009507; GO:0044715; GO:0046872 14229 XM_044328585.1 0 0 0 1 26 Q94K49 7.54e-25 Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1 (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) epigenetic regulation of gene expression [GO:0040029] GO:0003682; GO:0004518; GO:0005634; GO:0035098; GO:0035102; GO:0040029; GO:0046872 14230 XM_029333245.2 0 0 0 496 0 NA NA NA NA NA NA 14231 XM_044315777.1 34 9 22 17 18 Q8BKW4 1.63e-117 rRNA N6-adenosine-methyltransferase ZCCHC4 (EC 2.1.1.-) (Zinc finger CCHC domain-containing protein 4) Mus musculus (Mouse) positive regulation of translation [GO:0045727]; rRNA methylation [GO:0031167] GO:0003676; GO:0005730; GO:0005737; GO:0008270; GO:0008988; GO:0031167; GO:0045727; GO:1904047 14232 XR_006392897.1 41 2 25 5 151 NA NA NA NA NA NA 14233 XM_029358119.2 12 24 5 17 11 NA NA NA NA NA NA 14234 XM_029330825.2 0 0 23 0 0 Q8IW92 1.36e-130 Beta-galactosidase-1-like protein 2 (EC 3.2.1.-) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975] GO:0004565; GO:0005576; GO:0005764; GO:0005773; GO:0005975 14235 XM_044320470.1 22 15 33 0 33 NA NA NA NA NA NA 14236 XM_044324071.1 33 66 56 105 84 NA NA NA NA NA NA 14237 XM_029350154.2 1331 626 665 937 1023 NA NA NA NA NA NA 14238 XM_044323013.1 574 0 0 0 0 Q5XJ85 4.04e-27 Myeloid differentiation primary response protein MyD88 Danio rerio (Zebrafish) (Brachydanio rerio) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; monocyte activation [GO:0042117]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; neutrophil activation involved in immune response [GO:0002283]; neutrophil chemotaxis [GO:0030593]; positive regulation of hematopoietic progenitor cell differentiation [GO:1901534]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of hematopoietic progenitor cell differentiation [GO:1901532]; response to molecule of bacterial origin [GO:0002237]; Toll signaling pathway [GO:0008063] GO:0002218; GO:0002237; GO:0002283; GO:0002755; GO:0005737; GO:0005886; GO:0006954; GO:0008063; GO:0030593; GO:0035325; GO:0042117; GO:0042742; GO:0043123; GO:0045087; GO:0050830; GO:0070976; GO:1901532; GO:1901534 14239 XR_006397253.1 6 16 1 0 18 NA NA NA NA NA NA 14240 XM_044314567.1 1 0 0 2 15 NA NA NA NA NA NA 14241 XM_044326525.1 3312 2277 1632 3487 2499 Q3SZ71 0 Mitochondrial-processing peptidase subunit beta (EC 3.4.24.64) (Beta-MPP) Bos taurus (Bovine) proteolysis [GO:0006508] GO:0004222; GO:0005759; GO:0006508; GO:0046872 14242 XM_044325459.1 43 14 53 22 79 NA NA NA NA NA NA 14243 XM_029348474.2 542 552 638 535 517 Q8BZM0 7.74e-40 Kelch-like protein 12 (CUL3-interacting protein 1) Mus musculus (Mouse) COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; protein monoubiquitination [GO:0006513]; Wnt signaling pathway [GO:0016055] GO:0006513; GO:0006888; GO:0014029; GO:0014032; GO:0016055; GO:0030127; GO:0030134; GO:0031463; GO:0034451; GO:0042802; GO:0043231; GO:0048208 14244 XM_029332677.2 748 1690 390 1233 2320 O17185 2.33e-38 Two pore potassium channel protein sup-9 (Suppressor of unc-93 protein 9) (n2P38) Caenorhabditis elegans potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of muscle contraction [GO:0006937]; stabilization of membrane potential [GO:0030322] GO:0005267; GO:0005886; GO:0006813; GO:0006937; GO:0015271; GO:0022841; GO:0030322; GO:0036195; GO:0055120; GO:0071805 14245 XM_029337721.2 37 91 19 0 0 Q7ZVM9 3.04e-24 RecQ-mediated genome instability protein 1 Danio rerio (Zebrafish) (Brachydanio rerio) DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; resolution of meiotic recombination intermediates [GO:0000712] GO:0000166; GO:0000712; GO:0000724; GO:0006260; GO:0016604; GO:0031422 14246 XM_029334282.2 399 336 491 535 223 NA NA NA NA NA NA 14247 XM_044320289.1 162 74 0 0 0 Q29611 1.13e-118 Battenin (Protein CLN3) Canis lupus familiaris (Dog) (Canis familiaris) amyloid precursor protein catabolic process [GO:0042987]; autophagosome-lysosome fusion [GO:0061909]; cellular water homeostasis [GO:0009992]; glycerophospholipid biosynthetic process [GO:0046474]; glycolipid transport [GO:0046836]; Golgi to lysosome transport [GO:0090160]; L-arginine transmembrane transport [GO:1903826]; learning or memory [GO:0007611]; lysosomal lumen acidification [GO:0007042]; lysosomal lumen pH elevation [GO:0035752]; lysosomal protein catabolic process [GO:1905146]; negative regulation of apoptotic process [GO:0043066]; phagosome-lysosome docking [GO:0090384]; phagosome-lysosome fusion [GO:0090385]; plasma membrane raft organization [GO:0044857]; positive regulation of caveolin-mediated endocytosis [GO:2001288]; positive regulation of Golgi to plasma membrane protein transport [GO:0042998]; positive regulation of pinocytosis [GO:0048549]; receptor-mediated endocytosis [GO:0006898]; regulation of arginine biosynthetic process [GO:1900079]; regulation of autophagosome maturation [GO:1901096]; regulation of cellular response to osmotic stress [GO:0106049]; regulation of cytoskeleton organization [GO:0051493]; regulation of fibroblast migration [GO:0010762]; regulation of modification of synaptic structure [GO:1905244]; regulation of phagosome maturation [GO:1905162]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of protein processing [GO:0070613]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic transmission, GABAergic [GO:0032228]; regulation of synaptic transmission, glutamatergic [GO:0051966]; renal potassium excretion [GO:0036359]; vesicle transport along microtubule [GO:0047496] GO:0000139; GO:0005634; GO:0005737; GO:0005764; GO:0005765; GO:0005769; GO:0005770; GO:0005783; GO:0005789; GO:0005794; GO:0005795; GO:0005802; GO:0005829; GO:0005886; GO:0005901; GO:0006898; GO:0007042; GO:0007611; GO:0008021; GO:0009992; GO:0010762; GO:0016020; GO:0031901; GO:0032228; GO:0035752; GO:0036359; GO:0042987; GO:0042998; GO:0043005; GO:0043066; GO:0044754; GO:0044857; GO:0045121; GO:0046474; GO:0046836; GO:0047496; GO:0048172; GO:0048549; GO:0051493; GO:0051861; GO:0051966; GO:0055037; GO:0061909; GO:0070613; GO:0090160; GO:0090384; GO:0090385; GO:0106049; GO:0120146; GO:1900079; GO:1901096; GO:1903076; GO:1903826; GO:1905146; GO:1905162; GO:1905244; GO:2001288 14248 XM_044323543.1 23 3 2 21 39 NA NA NA NA NA NA 14249 XM_029346183.2 750 948 536 317 400 NA NA NA NA NA NA 14250 XM_044323161.1 17 0 1 0 0 Q96AY4 9.22e-52 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14251 XM_044323161.1 17 0 1 0 0 Q96AY4 1.39e-47 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14252 XM_044323161.1 17 0 1 0 0 Q96AY4 1.24e-45 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14253 XM_044323161.1 17 0 1 0 0 Q96AY4 1.48e-45 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14254 XM_044323161.1 17 0 1 0 0 Q96AY4 7.64e-45 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14255 XM_044323161.1 17 0 1 0 0 Q96AY4 9.99e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14256 XM_044323161.1 17 0 1 0 0 Q96AY4 1.18e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14257 XM_044323161.1 17 0 1 0 0 Q96AY4 2.9e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14258 XM_044323161.1 17 0 1 0 0 Q96AY4 1.23e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14259 XM_044323161.1 17 0 1 0 0 Q96AY4 5.91e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14260 XM_044323161.1 17 0 1 0 0 Q96AY4 1.54e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14261 XM_044323161.1 17 0 1 0 0 Q96AY4 1.88e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14262 XM_029353509.2 89 100 32 37 44 A2VDD2 5.44e-30 Dynein light chain Tctex-type 5-B (Tctex1 domain-containing protein 1-B) Xenopus laevis (African clawed frog) NA NA 14263 XM_029355915.2 0 271 226 49 45 C9D7C2 0 Voltage-dependent calcium channel type A subunit alpha-1 (Cacophony protein) Apis mellifera (Honeybee) regulation of ion transmembrane transport [GO:0034765] GO:0005245; GO:0005509; GO:0005891; GO:0034765 14264 XM_029333990.2 175 43 177 212 263 NA NA NA NA NA NA 14265 XM_044309207.1 49 0 0 87 255 NA NA NA NA NA NA 14266 XM_029334536.2 11 32 13 19 12 NA NA NA NA NA NA 14267 XM_029339963.2 2536 1738 1137 1666 2270 O35704 1.33e-169 Serine palmitoyltransferase 1 (EC 2.3.1.50) (Long chain base biosynthesis protein 1) (LCB 1) (Serine-palmitoyl-CoA transferase 1) (SPT 1) (SPT1) Mus musculus (Mouse) ceramide biosynthetic process [GO:0046513]; lipophagy [GO:0061724]; positive regulation of lipophagy [GO:1904504]; regulation of fat cell apoptotic process [GO:1904649]; sphinganine biosynthetic process [GO:0046511]; sphingolipid biosynthetic process [GO:0030148]; sphingolipid metabolic process [GO:0006665]; sphingomyelin biosynthetic process [GO:0006686]; sphingosine biosynthetic process [GO:0046512] GO:0004758; GO:0005783; GO:0005789; GO:0006665; GO:0006686; GO:0017059; GO:0030148; GO:0030170; GO:0035339; GO:0046511; GO:0046512; GO:0046513; GO:0061724; GO:1904504; GO:1904649 14268 XM_044326780.1 30 2 12 0 49 NA NA NA NA NA NA 14269 XM_029342217.2 554 291 384 727 1076 Q05D32 4.86e-113 CTD small phosphatase-like protein 2 (CTDSP-like 2) (EC 3.1.3.-) Homo sapiens (Human) negative regulation of BMP signaling pathway [GO:0030514]; positive regulation of protein export from nucleus [GO:0046827]; protein dephosphorylation [GO:0006470]; protein export from nucleus [GO:0006611] GO:0004721; GO:0005654; GO:0006470; GO:0006611; GO:0008420; GO:0030514; GO:0046827 14270 XR_006396197.1 20 35 32 51 60 NA NA NA NA NA NA 14271 XM_044313200.1 34 27 26 15 18 NA NA NA NA NA NA 14272 XM_029335341.2 1452 1196 449 899 659 NA NA NA NA NA NA 14273 XM_044315868.1 6 0 6 41 49 NA NA NA NA NA NA 14274 XM_044309400.1 4 1 6 11 10 NA NA NA NA NA NA 14275 XM_044312960.1 40 18 0 2 2 Q8K3Z0 3.08e-35 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 14276 XM_044320486.1 296 313 147 311 237 NA NA NA NA NA NA 14277 XR_006395744.1 43 68 3 13 21 NA NA NA NA NA NA 14278 XR_003826723.2 558 540 453 714 778 Q0IJ33 8.97e-144 E3 ubiquitin-protein ligase TM129 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TM129) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) response to unfolded protein [GO:0006986] GO:0005789; GO:0006986; GO:0046872; GO:0061630 14279 XM_029350134.2 1102 964 456 610 548 NA NA NA NA NA NA 14280 XM_044317114.1 79 83 82 26 151 NA NA NA NA NA NA 14281 XM_029329115.2 1159 620 535 978 881 L0N7N1 0 Kinesin-like protein KIF14 Mus musculus (Mouse) activation of protein kinase activity [GO:0032147]; cell division [GO:0051301]; cell proliferation in forebrain [GO:0021846]; cerebellar cortex development [GO:0021695]; cerebellar granular layer structural organization [GO:0021685]; cerebellar Purkinje cell layer structural organization [GO:0021693]; cerebral cortex development [GO:0021987]; establishment of protein localization [GO:0045184]; hippocampus development [GO:0021766]; microtubule-based movement [GO:0007018]; mitotic metaphase plate congression [GO:0007080]; negative regulation of apoptotic process [GO:0043066]; negative regulation of integrin activation [GO:0033624]; negative regulation of neuron apoptotic process [GO:0043524]; olfactory bulb development [GO:0021772]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokinesis [GO:0032467]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of cell adhesion [GO:0030155]; regulation of cell growth [GO:0001558]; regulation of cell maturation [GO:1903429]; regulation of cell migration [GO:0030334]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of myelination [GO:0031641]; regulation of neuron apoptotic process [GO:0043523]; regulation of Rap protein signal transduction [GO:0032487]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; substrate adhesion-dependent cell spreading [GO:0034446] GO:0001558; GO:0003777; GO:0005524; GO:0005634; GO:0005829; GO:0005871; GO:0005874; GO:0005886; GO:0007018; GO:0007080; GO:0008017; GO:0008284; GO:0008574; GO:0010389; GO:0015631; GO:0016020; GO:0016887; GO:0019901; GO:0021685; GO:0021693; GO:0021695; GO:0021766; GO:0021772; GO:0021846; GO:0021987; GO:0030155; GO:0030165; GO:0030334; GO:0030496; GO:0031146; GO:0031641; GO:0032147; GO:0032467; GO:0032487; GO:0033624; GO:0034446; GO:0043066; GO:0043161; GO:0043523; GO:0043524; GO:0045184; GO:0051233; GO:0051301; GO:0090543; GO:1903429; GO:2000045 14282 XM_044307021.1 118 62 30 63 167 Q7RTR2 1.62e-53 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 14283 XM_044307021.1 118 62 30 63 167 Q7RTR2 9.88e-51 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 14284 XM_044307021.1 118 62 30 63 167 Q7RTR2 6.09e-49 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 14285 XM_044307021.1 118 62 30 63 167 Q7RTR2 5.71e-48 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 14286 XM_029350593.2 43 21 13 25 104 Q4KM95 8.85e-42 Leucine-rich repeat-containing protein 42 Rattus norvegicus (Rat) NA NA 14287 XR_003827176.2 76 76 133 159 187 NA NA NA NA NA NA 14288 XM_029358305.2 109 106 84 188 128 Q6DJ06 5.84e-54 LIM domain transcription factor LMO4.2 (LIM domain only protein 4.2) (LMO-4.2) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell differentiation [GO:0030154]; gastrulation [GO:0007369]; mesoderm development [GO:0007498]; negative regulation of neuron differentiation [GO:0045665]; nervous system development [GO:0007399]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0003712; GO:0007369; GO:0007399; GO:0007498; GO:0030154; GO:0045665; GO:0045944; GO:0046872 14289 XM_044327833.1 50 8 0 6 0 NA NA NA NA NA NA 14290 XR_006394320.1 32 29 47 66 33 NA NA NA NA NA NA 14291 XM_044311631.1 23 1 4 0 56 NA NA NA NA NA NA 14292 XR_006395981.1 18 13 31 8 95 NA NA NA NA NA NA 14293 XM_029327938.2 33 13 10 0 14 NA NA NA NA NA NA 14294 XM_044307153.1 2115 1556 788 1576 1035 I3LHK5 5.73e-136 Actin-related protein 10 Sus scrofa (Pig) microtubule-based movement [GO:0007018]; retrograde axonal transport of mitochondrion [GO:0098958] GO:0005869; GO:0007018; GO:0098958; GO:1904115 14295 XM_044329314.1 748 999 519 459 852 Q91ZI0 3.06e-64 Cadherin EGF LAG seven-pass G-type receptor 3 Mus musculus (Mouse) axonal fasciculation [GO:0007413]; cell-cell adhesion [GO:0098609]; cilium assembly [GO:0060271]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; planar cell polarity pathway involved in axon guidance [GO:1904938]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] GO:0001932; GO:0004930; GO:0005509; GO:0005886; GO:0007156; GO:0007413; GO:0032880; GO:0036514; GO:0036515; GO:0060271; GO:0097475; GO:0098609; GO:1904938 14296 XM_044329314.1 748 999 519 459 852 Q91ZI0 4.27e-46 Cadherin EGF LAG seven-pass G-type receptor 3 Mus musculus (Mouse) axonal fasciculation [GO:0007413]; cell-cell adhesion [GO:0098609]; cilium assembly [GO:0060271]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; planar cell polarity pathway involved in axon guidance [GO:1904938]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] GO:0001932; GO:0004930; GO:0005509; GO:0005886; GO:0007156; GO:0007413; GO:0032880; GO:0036514; GO:0036515; GO:0060271; GO:0097475; GO:0098609; GO:1904938 14297 XM_044329314.1 748 999 519 459 852 Q91ZI0 2.27e-37 Cadherin EGF LAG seven-pass G-type receptor 3 Mus musculus (Mouse) axonal fasciculation [GO:0007413]; cell-cell adhesion [GO:0098609]; cilium assembly [GO:0060271]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; planar cell polarity pathway involved in axon guidance [GO:1904938]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] GO:0001932; GO:0004930; GO:0005509; GO:0005886; GO:0007156; GO:0007413; GO:0032880; GO:0036514; GO:0036515; GO:0060271; GO:0097475; GO:0098609; GO:1904938 14298 XR_006394516.1 708 437 290 336 351 P25291 1.36e-21 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 14299 XM_029334126.2 805 435 436 451 475 Q96P53 5.16e-159 WD repeat and FYVE domain-containing protein 2 (Propeller-FYVE protein) (Prof) (WD40- and FYVE domain-containing protein 2) (Zinc finger FYVE domain-containing protein 22) Homo sapiens (Human) positive regulation of fat cell differentiation [GO:0045600]; positive regulation of protein phosphorylation [GO:0001934] GO:0001934; GO:0005769; GO:0031982; GO:0043231; GO:0045600; GO:0046872 14300 XM_029344071.2 21 0 51 144 5 NA NA NA NA NA NA 14301 XM_044314138.1 0 0 162 0 0 NA NA NA NA NA NA 14302 XM_044321423.1 34 9 4 13 30 Q91ZI0 2.57e-65 Cadherin EGF LAG seven-pass G-type receptor 3 Mus musculus (Mouse) axonal fasciculation [GO:0007413]; cell-cell adhesion [GO:0098609]; cilium assembly [GO:0060271]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; planar cell polarity pathway involved in axon guidance [GO:1904938]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] GO:0001932; GO:0004930; GO:0005509; GO:0005886; GO:0007156; GO:0007413; GO:0032880; GO:0036514; GO:0036515; GO:0060271; GO:0097475; GO:0098609; GO:1904938 14303 XM_044321423.1 34 9 4 13 30 Q91ZI0 2.43e-45 Cadherin EGF LAG seven-pass G-type receptor 3 Mus musculus (Mouse) axonal fasciculation [GO:0007413]; cell-cell adhesion [GO:0098609]; cilium assembly [GO:0060271]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; planar cell polarity pathway involved in axon guidance [GO:1904938]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] GO:0001932; GO:0004930; GO:0005509; GO:0005886; GO:0007156; GO:0007413; GO:0032880; GO:0036514; GO:0036515; GO:0060271; GO:0097475; GO:0098609; GO:1904938 14304 XM_044321423.1 34 9 4 13 30 Q91ZI0 6.1e-38 Cadherin EGF LAG seven-pass G-type receptor 3 Mus musculus (Mouse) axonal fasciculation [GO:0007413]; cell-cell adhesion [GO:0098609]; cilium assembly [GO:0060271]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; planar cell polarity pathway involved in axon guidance [GO:1904938]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] GO:0001932; GO:0004930; GO:0005509; GO:0005886; GO:0007156; GO:0007413; GO:0032880; GO:0036514; GO:0036515; GO:0060271; GO:0097475; GO:0098609; GO:1904938 14305 XR_006391369.1 1881 1642 1190 2152 1707 A8TX70 8.54e-21 Collagen alpha-5(VI) chain (Collagen alpha-1(XXIX) chain) (von Willebrand factor A domain-containing protein 4) Homo sapiens (Human) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030020; GO:0030198; GO:0062023 14306 XM_044313994.1 306 85 168 68 576 P11369 9.02e-29 LINE-1 retrotransposable element ORF2 protein (ORF2p) (Long interspersed element-1) (L1) (Retrovirus-related Pol polyprotein LINE-1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)] Mus musculus (Mouse) DNA recombination [GO:0006310] GO:0003964; GO:0004519; GO:0006310; GO:0046872 14307 XM_029329207.2 222 91 76 187 239 NA NA NA NA NA NA 14308 XM_044328218.1 80 135 33 58 51 NA NA NA NA NA NA 14309 XM_029342451.2 325 340 202 206 296 Q6IRT3 1.17e-33 PCNA-interacting partner (PARI) (PARP-1 binding protein) (PARP1-binding protein) (PARPBP) Mus musculus (Mouse) DNA repair [GO:0006281]; negative regulation of double-strand break repair via homologous recombination [GO:2000042] GO:0000785; GO:0003677; GO:0005654; GO:0005737; GO:0006281; GO:2000042 14310 XR_006395805.1 0 0 0 19 0 NA NA NA NA NA NA 14311 XM_044311991.1 68 40 0 38 66 NA NA NA NA NA NA 14312 XM_029341050.2 133 85 92 115 153 NA NA NA NA NA NA 14313 XM_044321922.1 0 53 0 0 0 Q8IRC7 8.68e-77 LIM/homeobox protein Awh (Protein arrowhead) Drosophila melanogaster (Fruit fly) compound eye development [GO:0048749]; imaginal disc development [GO:0007444]; neuron differentiation [GO:0030182]; regulation of DNA-templated transcription [GO:0006355]; regulation of gene expression [GO:0010468]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000977; GO:0000981; GO:0003700; GO:0005634; GO:0006355; GO:0006357; GO:0007444; GO:0010468; GO:0030182; GO:0046872; GO:0048749 14314 XM_044317869.1 1 0 0 46 30 Q96CG8 4.55e-40 Collagen triple helix repeat-containing protein 1 Homo sapiens (Human) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005576; GO:0005581; GO:0005615; GO:0016477; GO:0016528; GO:0017147; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0062023; GO:0090090; GO:0090103; GO:0090177 14315 XM_029331483.2 0 0 189 666 60 Q6PDQ2 0 Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC 3.6.4.12) Mus musculus (Mouse) chromatin remodeling [GO:0006338]; histone deacetylation [GO:0016575]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of cell fate specification [GO:0042659]; regulation of stem cell differentiation [GO:2000736]; regulation of synapse assembly [GO:0051963]; terminal button organization [GO:0072553] GO:0000122; GO:0000781; GO:0000785; GO:0001221; GO:0003677; GO:0003682; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0006338; GO:0010629; GO:0016575; GO:0016581; GO:0016887; GO:0032991; GO:0032993; GO:0042393; GO:0042659; GO:0042826; GO:0045892; GO:0045893; GO:0046872; GO:0051963; GO:0061629; GO:0072553; GO:0090575; GO:0140297; GO:0140658; GO:0150048; GO:2000736 14316 XM_029331483.2 0 0 189 666 60 Q6PDQ2 6.27e-80 Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC 3.6.4.12) Mus musculus (Mouse) chromatin remodeling [GO:0006338]; histone deacetylation [GO:0016575]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of cell fate specification [GO:0042659]; regulation of stem cell differentiation [GO:2000736]; regulation of synapse assembly [GO:0051963]; terminal button organization [GO:0072553] GO:0000122; GO:0000781; GO:0000785; GO:0001221; GO:0003677; GO:0003682; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0006338; GO:0010629; GO:0016575; GO:0016581; GO:0016887; GO:0032991; GO:0032993; GO:0042393; GO:0042659; GO:0042826; GO:0045892; GO:0045893; GO:0046872; GO:0051963; GO:0061629; GO:0072553; GO:0090575; GO:0140297; GO:0140658; GO:0150048; GO:2000736 14317 XR_006397714.1 0 21 24 0 43 NA NA NA NA NA NA 14318 XM_029356319.2 49 51 0 0 0 NA NA NA NA NA NA 14319 XM_044316990.1 0 0 0 24 29 NA NA NA NA NA NA 14320 XM_044307574.1 3416 4218 3930 5034 3427 Q8BN59 3.71e-36 La-related protein 6 (Acheron) (Achn) (La ribonucleoprotein domain family member 6) Mus musculus (Mouse) positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of mRNA binding [GO:1902416]; positive regulation of translation [GO:0045727]; RNA processing [GO:0006396] GO:0003723; GO:0003729; GO:0005634; GO:0005737; GO:0005844; GO:0006396; GO:0017022; GO:0032967; GO:0035613; GO:0045727; GO:0048027; GO:1902416; GO:1990825; GO:1990904 14321 XM_029331379.2 154 112 78 151 206 NA NA NA NA NA NA 14322 XM_029349462.2 7 4 0 0 9 NA NA NA NA NA NA 14323 XM_044319070.1 0 71 21 10 22 Q9VEU6 2.69e-110 Soluble guanylate cyclase 89Da (EC 4.6.1.2) Drosophila melanogaster (Fruit fly) cGMP-mediated signaling [GO:0019934]; nitric oxide-cGMP-mediated signaling pathway [GO:0038060]; response to hypoxia [GO:0001666]; response to oxygen levels [GO:0070482]; response to reactive oxygen species [GO:0000302] GO:0000302; GO:0001666; GO:0004383; GO:0005525; GO:0008074; GO:0019899; GO:0019934; GO:0020037; GO:0038060; GO:0046872; GO:0070482 14324 XM_029334414.2 579 724 243 740 170 NA NA NA NA NA NA 14325 XM_029344515.2 84 19 34 68 67 NA NA NA NA NA NA 14326 XM_044320317.1 0 40 0 0 5 NA NA NA NA NA NA 14327 XM_029323716.2 61 0 173 14 14 P25931 5.02e-28 RYamide receptor (Neuropeptide Y-like receptor) (NPY-R) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218] GO:0001653; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0016020 14328 XM_029333921.2 269 343 112 320 229 NA NA NA NA NA NA 14329 XM_029338003.2 265 420 86 259 202 NA NA NA NA NA NA 14330 XM_029344562.2 56 0 186 60 108 Q91VL8 7.17e-33 Telomeric repeat-binding factor 2-interacting protein 1 (TERF2-interacting telomeric protein 1) (TRF2-interacting telomeric protein 1) (Repressor/activator protein 1 homolog) (RAP1 homolog) Mus musculus (Mouse) negative regulation of DNA recombination at telomere [GO:0048239]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of telomere maintenance [GO:0032205]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein acetylation [GO:1901985]; positive regulation of telomere maintenance [GO:0032206]; protein localization to chromosome, telomeric region [GO:0070198]; regulation of DNA-templated transcription [GO:0006355]; regulation of double-strand break repair via homologous recombination [GO:0010569]; regulation of telomere maintenance [GO:0032204]; telomere capping [GO:0016233]; telomere maintenance [GO:0000723]; telomere maintenance via telomere lengthening [GO:0010833] GO:0000723; GO:0000781; GO:0000783; GO:0001673; GO:0001933; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006355; GO:0010569; GO:0010833; GO:0016233; GO:0016604; GO:0019902; GO:0032204; GO:0032205; GO:0032206; GO:0033138; GO:0042162; GO:0043123; GO:0048239; GO:0051092; GO:0070187; GO:0070198; GO:0098505; GO:1901224; GO:1901985 14331 XR_006397492.1 58 24 56 21 10 Q6IQ20 3.1e-95 N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D (N-acyl phosphatidylethanolamine phospholipase D) (NAPE-PLD) (NAPE-hydrolyzing phospholipase D) (EC 3.1.4.54) Homo sapiens (Human) host-mediated regulation of intestinal microbiota composition [GO:0048874]; N-acylethanolamine metabolic process [GO:0070291]; N-acylphosphatidylethanolamine metabolic process [GO:0070292]; phospholipid catabolic process [GO:0009395]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of inflammatory response [GO:0050729]; retinoid metabolic process [GO:0001523]; temperature homeostasis [GO:0001659] GO:0000139; GO:0001523; GO:0001659; GO:0005635; GO:0005654; GO:0005737; GO:0005769; GO:0005794; GO:0008270; GO:0009395; GO:0031901; GO:0032052; GO:0042622; GO:0042802; GO:0043227; GO:0048874; GO:0050729; GO:0070062; GO:0070290; GO:0070291; GO:0070292; GO:0090336; GO:0102200 14332 XR_006397492.1 58 24 56 21 10 Q6IQ20 3.1e-95 N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D (N-acyl phosphatidylethanolamine phospholipase D) (NAPE-PLD) (NAPE-hydrolyzing phospholipase D) (EC 3.1.4.54) Homo sapiens (Human) host-mediated regulation of intestinal microbiota composition [GO:0048874]; N-acylethanolamine metabolic process [GO:0070291]; N-acylphosphatidylethanolamine metabolic process [GO:0070292]; phospholipid catabolic process [GO:0009395]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of inflammatory response [GO:0050729]; retinoid metabolic process [GO:0001523]; temperature homeostasis [GO:0001659] GO:0000139; GO:0001523; GO:0001659; GO:0005635; GO:0005654; GO:0005737; GO:0005769; GO:0005794; GO:0008270; GO:0009395; GO:0031901; GO:0032052; GO:0042622; GO:0042802; GO:0043227; GO:0048874; GO:0050729; GO:0070062; GO:0070290; GO:0070291; GO:0070292; GO:0090336; GO:0102200 14333 XM_044318988.1 40 102 30 135 54 P70196 1.29e-75 TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6) Mus musculus (Mouse) activation of NF-kappaB-inducing kinase activity [GO:0007250]; activation of protein kinase activity [GO:0032147]; animal organ morphogenesis [GO:0009887]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; bone remodeling [GO:0046849]; bone resorption [GO:0045453]; cell development [GO:0048468]; cellular response to cytokine stimulus [GO:0071345]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-17-mediated signaling pathway [GO:0097400]; JNK cascade [GO:0007254]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin production [GO:0002637]; response to interleukin-1 [GO:0070555]; signal transduction [GO:0007165]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000122; GO:0000209; GO:0001503; GO:0001701; GO:0001843; GO:0002637; GO:0002726; GO:0004842; GO:0005164; GO:0005634; GO:0005737; GO:0005811; GO:0005829; GO:0005886; GO:0005938; GO:0006955; GO:0006974; GO:0007165; GO:0007249; GO:0007250; GO:0007254; GO:0008270; GO:0009887; GO:0009898; GO:0016567; GO:0019221; GO:0019886; GO:0019901; GO:0030316; GO:0031435; GO:0031624; GO:0031625; GO:0031663; GO:0031666; GO:0031996; GO:0032147; GO:0032735; GO:0032743; GO:0032755; GO:0032813; GO:0032991; GO:0033209; GO:0035631; GO:0042088; GO:0042102; GO:0042475; GO:0042802; GO:0042826; GO:0042981; GO:0043011; GO:0043122; GO:0043123; GO:0043422; GO:0043507; GO:0045453; GO:0045672; GO:0045892; GO:0045944; GO:0046330; GO:0046849; GO:0047485; GO:0048468; GO:0048471; GO:0048661; GO:0050852; GO:0051091; GO:0051092; GO:0051865; GO:0061630; GO:0070498; GO:0070534; GO:0070555; GO:0071222; GO:0071345; GO:0097400; GO:1901224; GO:1904996; GO:2000679 14334 XM_044316618.1 7 0 4 0 4 P0CT40 1.87e-81 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 14335 XR_006395060.1 5 0 3 0 13 NA NA NA NA NA NA 14336 XR_006392773.1 66 50 108 53 145 NA NA NA NA NA NA 14337 XM_029323970.2 3 6 0 0 10 O93530 6.59e-47 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN (Focus-forming activity 1) (FFA-1) (Werner syndrome protein homolog) [Includes: 3'-5' exonuclease (EC 3.1.-.-); ATP-dependent helicase (EC 3.6.4.12)] Xenopus laevis (African clawed frog) DNA metabolic process [GO:0006259]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260] GO:0000287; GO:0003677; GO:0005524; GO:0005654; GO:0005730; GO:0006259; GO:0006260; GO:0006281; GO:0006310; GO:0008408; GO:0016887; GO:0030145; GO:0043138 14338 XM_029339933.2 899 197 367 288 445 A0JM56 0 Leucine-rich repeat-containing protein 9 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737 14339 XM_029340034.2 5634 3436 2647 3877 1911 Q6LAF1 3.08e-50 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 14340 XM_044308774.1 25 0 14 23 28 NA NA NA NA NA NA 14341 XM_029327976.2 13 0 0 4 5 NA NA NA NA NA NA 14342 XM_044310110.1 138 109 223 0 126 NA NA NA NA NA NA 14343 XM_029354782.2 570 275 140 538 539 Q58EK3 1.84e-65 PI-PLC X domain-containing protein 3 Danio rerio (Zebrafish) (Brachydanio rerio) lipid catabolic process [GO:0016042]; signal transduction [GO:0007165] GO:0007165; GO:0008081; GO:0016042; GO:0045202 14344 XM_029350721.2 0 63 0 76 91 NA NA NA NA NA NA 14345 XM_044311829.1 126 20 45 53 20 NA NA NA NA NA NA 14346 XM_044309515.1 31 23 35 18 183 NA NA NA NA NA NA 14347 XM_044328125.1 615 584 465 520 330 C3YWU0 0 Alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucoside fucohydrolase) Branchiostoma floridae (Florida lancelet) (Amphioxus) fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139] GO:0004560; GO:0005576; GO:0005764; GO:0006004; GO:0016139 14348 XM_029355741.2 54 62 29 120 138 NA NA NA NA NA NA 14349 XM_029339258.2 0 0 183 548 213 Q9Y5B9 0 FACT complex subunit SPT16 (Chromatin-specific transcription elongation factor 140 kDa subunit) (FACT 140 kDa subunit) (FACTp140) (Facilitates chromatin transcription complex subunit SPT16) (hSPT16) Homo sapiens (Human) DNA repair [GO:0006281]; DNA replication [GO:0006260]; nucleosome assembly [GO:0006334]; nucleosome disassembly [GO:0006337]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; transcription by RNA polymerase II [GO:0006366]; transcription elongation by RNA polymerase II promoter [GO:0006368] GO:0003723; GO:0005634; GO:0005654; GO:0006260; GO:0006281; GO:0006334; GO:0006337; GO:0006366; GO:0006368; GO:0031491; GO:0032786; GO:0035101 14350 XR_003822816.2 191 38 37 26 91 NA NA NA NA NA NA 14351 XM_029339910.2 33 5 52 31 67 Q3T1J2 5.32e-98 Lysophospholipid acyltransferase 2 (LPLAT 2) (EC 2.3.1.-) (1-acylglycerophosphate O-acyltransferase) (EC 2.3.1.51) (1-acylglycerophosphocholine O-acyltransferase) (EC 2.3.1.23) (1-acylglycerophosphoethanolamine O-acyltransferase) (EC 2.3.1.n7) (Lysophosphatidic acid acyltransferase) (LPAAT) (Lyso-PA acyltransferase) (Lysophosphatidylcholine acyltransferase) (LPCAT) (Lyso-PC acyltransferase) (Lysophosphatidylcholine acyltransferase 4) (Lyso-PC acyltransferase 4) (Lysophosphatidylethanolamine acyltransferase) (LPEAT) (Lyso-PE acyltransferase) (Membrane-bound O-acyltransferase domain-containing protein 2) (O-acyltransferase domain-containing protein 2) Rattus norvegicus (Rat) lipid modification [GO:0030258]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; phosphatidylserine acyl-chain remodeling [GO:0036150]; phospholipid biosynthetic process [GO:0008654]; regulation of chondrocyte differentiation [GO:0032330] GO:0003841; GO:0005789; GO:0008654; GO:0016020; GO:0016746; GO:0030258; GO:0032330; GO:0036150; GO:0036151; GO:0036152; GO:0047184; GO:0106262; GO:0106263 14352 XM_029328543.2 1676 1163 1471 1678 1564 E6ZIJ1 1.18e-103 RanBP-type and C3HC4-type zinc finger-containing protein 1 (EC 2.3.2.31) (Heme-oxidized IRP2 ubiquitin ligase 1 homolog) (HOIL-1) (Heme-oxidized IRP2 ubiquitin transferase 1 homolog) Dicentrarchus labrax (European seabass) (Morone labrax) defense response to bacterium [GO:0042742]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein linear polyubiquitination [GO:0097039] GO:0016740; GO:0042742; GO:0043123; GO:0043130; GO:0046872; GO:0071797; GO:0097039 14353 XM_044319682.1 38 0 163 0 134 P48416 1.06e-73 Cytochrome P450 10 (EC 1.14.-.-) (CYPX) Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004497; GO:0005506; GO:0016705; GO:0020037 14354 XM_044319682.1 38 0 163 0 134 P48416 1.06e-73 Cytochrome P450 10 (EC 1.14.-.-) (CYPX) Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004497; GO:0005506; GO:0016705; GO:0020037 14355 XM_029332123.2 964 597 500 919 809 Q5F485 0 ATP-dependent RNA helicase DDX42 (EC 3.6.4.13) (DEAD box protein 42) Gallus gallus (Chicken) protein localization [GO:0008104]; regulation of apoptotic process [GO:0042981] GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005737; GO:0008104; GO:0016887; GO:0042981 14356 XR_006393088.1 41 2 25 5 151 NA NA NA NA NA NA 14357 XM_044319635.1 0 104 0 0 17 O94762 0 ATP-dependent DNA helicase Q5 (EC 3.6.4.12) (DNA helicase, RecQ-like type 5) (RecQ5) (RecQ protein-like 5) Homo sapiens (Human) cell division [GO:0051301]; cellular response to camptothecin [GO:0072757]; cellular response to ketone [GO:1901655]; cellular response to xenobiotic stimulus [GO:0071466]; chromosome separation [GO:0051304]; DNA duplex unwinding [GO:0032508]; DNA metabolic process [GO:0006259]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724]; mitotic cell cycle [GO:0000278]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; negative regulation of transcription elongation by RNA polymerase II [GO:0034244]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414] GO:0000278; GO:0000724; GO:0000993; GO:0003676; GO:0003678; GO:0005524; GO:0005634; GO:0005654; GO:0005694; GO:0005737; GO:0005829; GO:0006259; GO:0006260; GO:0006268; GO:0006281; GO:0006310; GO:0009378; GO:0016591; GO:0016887; GO:0032508; GO:0034244; GO:0042802; GO:0043138; GO:0051301; GO:0051304; GO:0071466; GO:0072757; GO:1901655; GO:1990414; GO:2000042 14358 XM_029351979.2 74 168 71 91 121 E9PZZ1 2.45e-37 PR domain zinc finger protein 13 (EC 2.1.1.-) (PR domain-containing protein 13) Mus musculus (Mouse) GABAergic neuron differentiation [GO:0097154]; hypothalamus cell differentiation [GO:0021979]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of gene expression [GO:0010468] GO:0000122; GO:0003677; GO:0003682; GO:0005634; GO:0010468; GO:0021979; GO:0022008; GO:0042054; GO:0046872; GO:0061629; GO:0097154 14359 XM_029352970.2 447 456 435 297 316 NA NA NA NA NA NA 14360 XM_044314127.1 75 17 13 124 12 NA NA NA NA NA NA 14361 XM_029348654.2 0 0 9 0 2 NA NA NA NA NA NA 14362 XR_006394470.1 20 0 0 2 2 NA NA NA NA NA NA 14363 XR_003822799.2 145 127 199 127 105 NA NA NA NA NA NA 14364 XM_044312714.1 232 380 33 274 75 NA NA NA NA NA NA 14365 XM_044324059.1 36 0 0 32 349 NA NA NA NA NA NA 14366 XM_029325533.2 150 57 101 393 237 NA NA NA NA NA NA 14367 XM_029349037.2 66 7 11 30 116 NA NA NA NA NA NA 14368 XM_044311783.1 66 236 37 107 153 NA NA NA NA NA NA 14369 XR_003825979.2 38 17 38 19 62 NA NA NA NA NA NA 14370 XM_044318223.1 1026 648 372 687 787 Q8K2L8 8.23e-126 Trafficking protein particle complex subunit 12 (Tetratricopeptide repeat protein 15) (TPR repeat protein 15) Mus musculus (Mouse) COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; metaphase plate congression [GO:0051310]; positive regulation of protein localization to kinetochore [GO:1905342]; regulation of kinetochore assembly [GO:0090234]; vesicle tethering [GO:0099022] GO:0000776; GO:0005634; GO:0005654; GO:0005737; GO:0005793; GO:0005794; GO:0006888; GO:0007030; GO:0030008; GO:0048208; GO:0048471; GO:0051310; GO:0090234; GO:0099022; GO:1905342; GO:1990072 14371 XM_044325259.1 118 89 11 129 22 Q14DL3 7.46e-49 Leucine-rich repeat and IQ domain-containing protein 3 (Leucine-rich repeat-containing protein 44) Mus musculus (Mouse) NA NA 14372 XM_029343253.2 75 52 64 58 162 P54278 0 Mismatch repair endonuclease PMS2 (EC 3.1.-.-) (DNA mismatch repair protein PMS2) (PMS1 protein homolog 2) Homo sapiens (Human) mismatch repair [GO:0006298]; response to xenobiotic stimulus [GO:0009410]; somatic hypermutation of immunoglobulin genes [GO:0016446] GO:0003677; GO:0004519; GO:0005524; GO:0005634; GO:0005654; GO:0005829; GO:0005886; GO:0006298; GO:0009410; GO:0016446; GO:0016887; GO:0032138; GO:0032300; GO:0032389; GO:0036464; GO:0140664 14373 XM_044310324.1 18 28 0 1 75 NA NA NA NA NA NA 14374 XM_044326735.1 89 103 8 64 7 NA NA NA NA NA NA 14375 XR_006397715.1 0 0 0 7 0 Q9JI78 5.3e-174 Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase (PNGase) (mPNGase) (EC 3.5.1.52) (N-glycanase 1) (Peptide:N-glycanase) Mus musculus (Mouse) ER-associated misfolded protein catabolic process [GO:0071712]; glycoprotein catabolic process [GO:0006516]; protein deglycosylation [GO:0006517]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515] GO:0000224; GO:0005634; GO:0005737; GO:0005829; GO:0006515; GO:0006516; GO:0006517; GO:0046872; GO:0062023; GO:0071712 14376 XM_029327891.2 0 0 268 202 96 Q4R630 4.9e-82 Kinetochore protein NDC80 homolog (Kinetochore protein Hec1) (Kinetochore-associated protein 2) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) attachment of mitotic spindle microtubules to kinetochore [GO:0051315]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; metaphase plate congression [GO:0051310]; mitotic spindle organization [GO:0007052]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267] GO:0000776; GO:0005634; GO:0007052; GO:0007059; GO:0031262; GO:0051301; GO:0051310; GO:0051315; GO:0090267; GO:0140483 14377 XM_044310346.1 40 24 364 312 1380 NA NA NA NA NA NA 14378 XM_029328960.2 562 522 247 435 743 O88696 1.51e-106 ATP-dependent Clp protease proteolytic subunit, mitochondrial (EC 3.4.21.92) (Endopeptidase Clp) Mus musculus (Mouse) membrane protein proteolysis [GO:0033619]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603] GO:0004175; GO:0004176; GO:0004252; GO:0005739; GO:0005759; GO:0006508; GO:0006515; GO:0009368; GO:0033619; GO:0042802; GO:0051117; GO:0051603 14379 XR_003826862.2 42 4 33 67 30 NA NA NA NA NA NA 14380 XM_029340835.2 44 0 0 0 0 Q864U6 3.66e-31 UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1 (Beta-1,3-GalNAc-T1) (EC 2.4.1.79) (Beta-1,3-galactosyltransferase 3) (Beta-1,3-GalTase 3) (Beta3Gal-T3) (Beta3GalT3) (b3Gal-T3) (Beta-3-Gx-T3) (Galactosylgalactosylglucosylceramide beta-D-acetyl-galactosaminyltransferase) (Globoside synthase) (UDP-N-acetylgalactosamine:globotriaosylceramide beta-1,3-N-acetylgalactosaminyltransferase) Sus scrofa (Pig) lipid metabolic process [GO:0006629]; oligosaccharide biosynthetic process [GO:0009312]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0006629; GO:0008194; GO:0008499; GO:0009312; GO:0016757; GO:0047273 14381 XM_044324119.1 61 49 18 34 19 NA NA NA NA NA NA 14382 XM_029330903.2 11 11 0 2 12 NA NA NA NA NA NA 14383 XM_044324334.1 53 35 49 98 53 G8HTB6 7.39e-44 ZP domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 14384 XR_003828596.2 23 0 4 1 75 NA NA NA NA NA NA 14385 XM_029346231.2 1290 822 1168 1243 636 NA NA NA NA NA NA 14386 XR_006394916.1 0 0 0 6 0 NA NA NA NA NA NA 14387 XM_029332587.2 295 194 192 168 447 NA NA NA NA NA NA 14388 XM_029340882.2 133 113 80 95 76 NA NA NA NA NA NA 14389 XM_029346520.2 42 11 48 7 146 Q9I8C7 7.98e-80 Neuronal acetylcholine receptor subunit alpha-10 (Alpha 10 nAChR) (Nicotinic acetylcholine receptor subunit alpha-10) (NACHR alpha-10) Gallus gallus (Chicken) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; response to auditory stimulus [GO:0010996]; signal transduction [GO:0007165] GO:0004888; GO:0005231; GO:0005262; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0010996; GO:0022848; GO:0030594; GO:0034220; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051899; GO:1904315 14390 XM_029346558.2 2410 1085 998 2083 1869 Q2PPJ7 0 Ral GTPase-activating protein subunit alpha-2 (250 kDa substrate of Akt) (AS250) (p220) Homo sapiens (Human) activation of GTPase activity [GO:0090630]; regulation of small GTPase mediated signal transduction [GO:0051056] GO:0005096; GO:0005615; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0046982; GO:0051056; GO:0090630 14391 XM_029346558.2 2410 1085 998 2083 1869 Q2PPJ7 8.86e-111 Ral GTPase-activating protein subunit alpha-2 (250 kDa substrate of Akt) (AS250) (p220) Homo sapiens (Human) activation of GTPase activity [GO:0090630]; regulation of small GTPase mediated signal transduction [GO:0051056] GO:0005096; GO:0005615; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0046982; GO:0051056; GO:0090630 14392 XM_044315465.1 3 0 0 6 4 NA NA NA NA NA NA 14393 XM_044318705.1 11 24 36 119 34 NA NA NA NA NA NA 14394 XM_044315468.1 7 0 0 0 0 NA NA NA NA NA NA 14395 XM_029347360.2 2234 1489 1488 2702 1920 Q0KL02 0 Triple functional domain protein (EC 2.7.11.1) Mus musculus (Mouse) axon guidance [GO:0007411]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of fat cell differentiation [GO:0045599]; neuron projection morphogenesis [GO:0048812]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; protein phosphorylation [GO:0006468] GO:0004674; GO:0005085; GO:0005524; GO:0005737; GO:0005769; GO:0006468; GO:0007411; GO:0019898; GO:0019899; GO:0042995; GO:0045599; GO:0048786; GO:0048812; GO:0050804; GO:0098685; GO:0098794; GO:0098978; GO:0099170; GO:0106310 14396 XM_029347360.2 2234 1489 1488 2702 1920 Q0KL02 6.53e-85 Triple functional domain protein (EC 2.7.11.1) Mus musculus (Mouse) axon guidance [GO:0007411]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of fat cell differentiation [GO:0045599]; neuron projection morphogenesis [GO:0048812]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; protein phosphorylation [GO:0006468] GO:0004674; GO:0005085; GO:0005524; GO:0005737; GO:0005769; GO:0006468; GO:0007411; GO:0019898; GO:0019899; GO:0042995; GO:0045599; GO:0048786; GO:0048812; GO:0050804; GO:0098685; GO:0098794; GO:0098978; GO:0099170; GO:0106310 14397 XM_029347360.2 2234 1489 1488 2702 1920 Q0KL02 6.92e-65 Triple functional domain protein (EC 2.7.11.1) Mus musculus (Mouse) axon guidance [GO:0007411]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of fat cell differentiation [GO:0045599]; neuron projection morphogenesis [GO:0048812]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; protein phosphorylation [GO:0006468] GO:0004674; GO:0005085; GO:0005524; GO:0005737; GO:0005769; GO:0006468; GO:0007411; GO:0019898; GO:0019899; GO:0042995; GO:0045599; GO:0048786; GO:0048812; GO:0050804; GO:0098685; GO:0098794; GO:0098978; GO:0099170; GO:0106310 14398 XM_029347360.2 2234 1489 1488 2702 1920 Q0KL02 1.21e-56 Triple functional domain protein (EC 2.7.11.1) Mus musculus (Mouse) axon guidance [GO:0007411]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of fat cell differentiation [GO:0045599]; neuron projection morphogenesis [GO:0048812]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; protein phosphorylation [GO:0006468] GO:0004674; GO:0005085; GO:0005524; GO:0005737; GO:0005769; GO:0006468; GO:0007411; GO:0019898; GO:0019899; GO:0042995; GO:0045599; GO:0048786; GO:0048812; GO:0050804; GO:0098685; GO:0098794; GO:0098978; GO:0099170; GO:0106310 14399 XM_029347360.2 2234 1489 1488 2702 1920 Q0KL02 2.97e-52 Triple functional domain protein (EC 2.7.11.1) Mus musculus (Mouse) axon guidance [GO:0007411]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of fat cell differentiation [GO:0045599]; neuron projection morphogenesis [GO:0048812]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; protein phosphorylation [GO:0006468] GO:0004674; GO:0005085; GO:0005524; GO:0005737; GO:0005769; GO:0006468; GO:0007411; GO:0019898; GO:0019899; GO:0042995; GO:0045599; GO:0048786; GO:0048812; GO:0050804; GO:0098685; GO:0098794; GO:0098978; GO:0099170; GO:0106310 14400 XM_029330819.2 2 0 0 1 10 NA NA NA NA NA NA 14401 XM_044324962.1 6 6 11 9 27 Q80XJ3 6.91e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 14402 XM_044324962.1 6 6 11 9 27 Q80XJ3 1.16e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 14403 XM_044324962.1 6 6 11 9 27 Q80XJ3 1.29e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 14404 XM_044324962.1 6 6 11 9 27 Q80XJ3 2.2e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 14405 XM_044324962.1 6 6 11 9 27 Q80XJ3 1.51e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 14406 XM_044324962.1 6 6 11 9 27 Q80XJ3 8.46e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 14407 XM_044324962.1 6 6 11 9 27 Q80XJ3 1.04e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 14408 XM_044324962.1 6 6 11 9 27 Q80XJ3 5.93e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 14409 XM_044324962.1 6 6 11 9 27 Q80XJ3 6.75e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 14410 XM_044324962.1 6 6 11 9 27 Q80XJ3 9.16e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 14411 XM_044324962.1 6 6 11 9 27 Q80XJ3 1.67e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 14412 XM_044324962.1 6 6 11 9 27 Q80XJ3 3.58e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 14413 XM_044324962.1 6 6 11 9 27 Q80XJ3 5.04e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 14414 XM_044313084.1 70 14 19 110 23 NA NA NA NA NA NA 14415 XM_029349851.2 610 458 395 383 302 A4QND0 1.18e-24 Ubiquitin-like protein 4A Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) tail-anchored membrane protein insertion into ER membrane [GO:0071816] GO:0005634; GO:0005829; GO:0071816; GO:0071818 14416 XM_044326323.1 0 65 0 0 16 B3EWZ6 1.12e-88 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 14417 XM_044326323.1 0 65 0 0 16 B3EWZ6 9.52e-87 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 14418 XM_044326323.1 0 65 0 0 16 B3EWZ6 9.55e-85 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 14419 XM_044326323.1 0 65 0 0 16 B3EWZ6 5.41e-81 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 14420 XM_044326323.1 0 65 0 0 16 B3EWZ6 1.41e-80 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 14421 XM_044326323.1 0 65 0 0 16 B3EWZ6 8.05e-76 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 14422 XM_044326323.1 0 65 0 0 16 B3EWZ6 8.2e-76 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 14423 XM_044326323.1 0 65 0 0 16 B3EWZ6 1.74e-75 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 14424 XM_044326323.1 0 65 0 0 16 B3EWZ6 4.59e-74 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 14425 XM_044326323.1 0 65 0 0 16 B3EWZ6 9.98e-73 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 14426 XM_044326323.1 0 65 0 0 16 B3EWZ6 2.64e-71 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 14427 XM_044326323.1 0 65 0 0 16 B3EWZ6 7.33e-68 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 14428 XM_044326323.1 0 65 0 0 16 B3EWZ6 1.12e-67 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 14429 XM_044326323.1 0 65 0 0 16 B3EWZ6 4.15e-65 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 14430 XM_044326323.1 0 65 0 0 16 B3EWZ6 1.93e-63 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 14431 XM_044326323.1 0 65 0 0 16 B3EWZ6 9.46e-61 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 14432 XM_044326323.1 0 65 0 0 16 B3EWZ6 3.81e-54 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 14433 XM_044326323.1 0 65 0 0 16 B3EWZ6 1.11e-51 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 14434 XM_044326323.1 0 65 0 0 16 B3EWZ6 1.59e-51 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 14435 XM_044326323.1 0 65 0 0 16 B3EWZ6 1.7e-51 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 14436 XM_044326323.1 0 65 0 0 16 B3EWZ6 5.65e-51 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 14437 XM_044326323.1 0 65 0 0 16 B3EWZ6 1.63e-50 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 14438 XM_044326323.1 0 65 0 0 16 B3EWZ6 1.22e-46 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 14439 XM_044326323.1 0 65 0 0 16 B3EWZ6 7.12e-43 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 14440 XM_044326323.1 0 65 0 0 16 B3EWZ6 3.49e-30 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 14441 XM_044326323.1 0 65 0 0 16 B3EWZ6 3.86e-27 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 14442 XR_003828351.1 5 0 0 9 18 NA NA NA NA NA NA 14443 XM_029346193.2 20 42 40 5 8 P07098 6.17e-135 Gastric triacylglycerol lipase (GL) (Gastric lipase) (EC 3.1.1.3) Homo sapiens (Human) lipid catabolic process [GO:0016042]; malate metabolic process [GO:0006108]; triglyceride metabolic process [GO:0006641] GO:0004806; GO:0005576; GO:0005739; GO:0006108; GO:0006641; GO:0008289; GO:0016042; GO:0016615; GO:0043231 14444 XM_029329012.2 86 49 38 85 95 F4JG10 4.12e-65 Endo-1,4-beta-xylanase 3 (AtXyn3) (Xylan endohydrolase 3) (Xylanase 3) (EC 3.2.1.8) Arabidopsis thaliana (Mouse-ear cress) xylan catabolic process [GO:0045493] GO:0031176; GO:0045493; GO:0110165 14445 XM_029329018.2 755 607 300 650 533 Q96KB5 7.8e-85 Lymphokine-activated killer T-cell-originated protein kinase (EC 2.7.12.2) (Cancer/testis antigen 84) (CT84) (MAPKK-like protein kinase) (Nori-3) (PDZ-binding kinase) (Spermatogenesis-related protein kinase) (SPK) (T-LAK cell-originated protein kinase) Homo sapiens (Human) cellular response to UV [GO:0034644]; mitotic cell cycle [GO:0000278]; negative regulation of inflammatory response [GO:0050728]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of stress-activated MAPK cascade [GO:0032873]; p38MAPK cascade [GO:0038066]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of mitotic DNA damage checkpoint [GO:1904291]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] GO:0000278; GO:0001933; GO:0004674; GO:0004706; GO:0004708; GO:0004713; GO:0005524; GO:0005634; GO:0018105; GO:0032435; GO:0032873; GO:0034644; GO:0038066; GO:0043161; GO:0050728; GO:0106310; GO:1904291 14446 XM_029355778.2 73 0 63 26 12 Q8CJ69 2.18e-97 BMP-binding endothelial regulator protein (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2) Mus musculus (Mouse) blood vessel development [GO:0001568]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; BMP signaling pathway [GO:0030509]; common-partner SMAD protein phosphorylation [GO:0007182]; endothelial cell activation [GO:0042118]; inner ear development [GO:0048839]; negative regulation of BMP signaling pathway [GO:0030514]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of sprouting angiogenesis [GO:1903672]; regulation of angiogenesis [GO:0045765]; regulation of endothelial cell migration [GO:0010594]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization [GO:0032880]; ureteric bud development [GO:0001657] GO:0001568; GO:0001657; GO:0002043; GO:0005576; GO:0005615; GO:0007182; GO:0010594; GO:0030509; GO:0030514; GO:0031012; GO:0032880; GO:0042118; GO:0045765; GO:0048839; GO:0060393; GO:0062023; GO:0070374; GO:1903672 14447 XM_029342587.2 354 112 18 133 130 Q8BH70 1.69e-117 F-box/LRR-repeat protein 4 (F-box and leucine-rich repeat protein 4) Mus musculus (Mouse) autophagy of mitochondrion [GO:0000422]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0000422; GO:0005758; GO:0016607; GO:0019005; GO:0031146 14448 XM_044326354.1 3 1 2 3 33 Q9M2U3 5.28e-27 Protein ALP1-like (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) NA GO:0000118; GO:0004518; GO:0046872 14449 XM_029336498.2 423 818 495 558 575 NA NA NA NA NA NA 14450 XM_029352163.2 645 1413 426 991 121 NA NA NA NA NA NA 14451 XM_029355057.2 447 300 86 216 157 NA NA NA NA NA NA 14452 XM_029323495.2 0 0 0 0 116 O46564 1.89e-25 Bone morphogenetic protein 2 (BMP-2) Oryctolagus cuniculus (Rabbit) BMP signaling pathway [GO:0030509]; BMP signaling pathway involved in heart induction [GO:0003130]; cardiac epithelial to mesenchymal transition [GO:0060317]; cardiocyte differentiation [GO:0035051]; cartilage development [GO:0051216]; epithelial to mesenchymal transition [GO:0001837]; mesenchymal cell differentiation [GO:0048762]; negative regulation of cardiac muscle cell differentiation [GO:2000726]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of Wnt signaling pathway involved in heart development [GO:0003308]; osteoblast differentiation [GO:0001649]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone mineralization [GO:0030501]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of cartilage development [GO:0061036]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ossification [GO:0045778]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of phosphatase activity [GO:0010922]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; SMAD protein signal transduction [GO:0060395]; telencephalon development [GO:0021537] GO:0000122; GO:0001649; GO:0001837; GO:0001934; GO:0001938; GO:0003130; GO:0003308; GO:0005125; GO:0005615; GO:0008083; GO:0008285; GO:0009986; GO:0010862; GO:0010922; GO:0019211; GO:0021537; GO:0030501; GO:0030509; GO:0035051; GO:0043065; GO:0045778; GO:0045786; GO:0045892; GO:0045944; GO:0046332; GO:0048762; GO:0051216; GO:0060317; GO:0060389; GO:0060395; GO:0061036; GO:0070700; GO:1900159; GO:2000726 14453 XM_029347823.2 2652 2024 2284 2643 2419 Q14642 3.85e-117 Inositol polyphosphate-5-phosphatase A (EC 3.1.3.56) (43 kDa inositol polyphosphate 5-phosphatase) (Type I inositol 1,4,5-trisphosphate 5-phosphatase) (5PTase) Homo sapiens (Human) inositol phosphate dephosphorylation [GO:0046855]; inositol phosphate metabolic process [GO:0043647]; inositol phosphate-mediated signaling [GO:0048016]; negative regulation of neuron death [GO:1901215]; phosphatidylinositol dephosphorylation [GO:0046856] GO:0004445; GO:0005886; GO:0016020; GO:0030425; GO:0042731; GO:0043647; GO:0046855; GO:0046856; GO:0048016; GO:0052658; GO:0052659; GO:1901215 14454 XM_044324950.1 1485 708 204 1061 389 NA NA NA NA NA NA 14455 XM_029325140.2 4456 3220 2574 4277 4390 Q92903 5.09e-146 Phosphatidate cytidylyltransferase 1 (EC 2.7.7.41) (CDP-DAG synthase 1) (CDP-DG synthase 1) (CDP-diacylglycerol synthase 1) (CDS 1) (CDP-diglyceride pyrophosphorylase 1) (CDP-diglyceride synthase 1) (CTP:phosphatidate cytidylyltransferase 1) Homo sapiens (Human) CDP-diacylglycerol biosynthetic process [GO:0016024]; lipid droplet formation [GO:0140042]; phosphatidylinositol biosynthetic process [GO:0006661]; phototransduction [GO:0007602]; positive regulation of fat cell differentiation [GO:0045600]; signal transduction [GO:0007165] GO:0004142; GO:0004605; GO:0005783; GO:0005789; GO:0006661; GO:0007165; GO:0007602; GO:0016020; GO:0016024; GO:0045600; GO:0140042 14456 XM_029339105.2 165 67 34 200 88 Q9NVV4 2.64e-42 Poly(A) RNA polymerase, mitochondrial (PAP) (EC 2.7.7.19) (PAP-associated domain-containing protein 1) (Polynucleotide adenylyltransferase) (Terminal uridylyltransferase 1) (TUTase 1) (mtPAP) Homo sapiens (Human) histone mRNA catabolic process [GO:0071044]; mRNA polyadenylation [GO:0006378]; RNA 3'-end processing [GO:0031123] GO:0000287; GO:0002134; GO:0003723; GO:0004652; GO:0005524; GO:0005654; GO:0005739; GO:0006378; GO:0016779; GO:0030145; GO:0031123; GO:0042802; GO:0042803; GO:0043231; GO:0071044; GO:1990817 14457 XM_029323883.2 2360 773 2955 2329 1937 Q5BK09 1.01e-22 DNA damage-regulated autophagy modulator protein 2 (Transmembrane protein 77) Rattus norvegicus (Rat) apoptotic process [GO:0006915]; autophagy [GO:0006914]; photoreceptor cell maintenance [GO:0045494]; regulation of autophagy [GO:0010506]; visual perception [GO:0007601] GO:0001917; GO:0005737; GO:0005764; GO:0005765; GO:0005794; GO:0006914; GO:0006915; GO:0007601; GO:0010506; GO:0016324; GO:0045494 14458 XM_044328229.1 242 255 72 35 123 Q9BX70 4.71e-71 BTB/POZ domain-containing protein 2 Homo sapiens (Human) neurogenesis [GO:0022008] GO:0000932; GO:0005829; GO:0022008 14459 XM_044328944.1 29 42 7 29 47 Q61184 8.67e-37 Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor) Mus musculus (Mouse) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; circadian rhythm [GO:0007623]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of insulin secretion [GO:0046676] GO:0004930; GO:0005886; GO:0007186; GO:0007193; GO:0007623; GO:0008502; GO:0042562; GO:0043025; GO:0043235; GO:0046676; GO:0097159 14460 XM_044313639.1 17 10 3 0 0 Q6DG03 6.86e-31 Cyclin-D-binding Myb-like transcription factor 1 Danio rerio (Zebrafish) (Brachydanio rerio) cell cycle [GO:0007049]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000976; GO:0000978; GO:0000981; GO:0003700; GO:0005634; GO:0006355; GO:0006357; GO:0007049 14461 XM_044314140.1 1 0 0 30 4 NA NA NA NA NA NA 14462 XM_029330961.2 0 0 0 8 76 D3ZZL9 8.62e-90 GRIP and coiled-coil domain-containing protein 2 (185 kDa Golgi coiled-coil protein) Rattus norvegicus (Rat) Golgi ribbon formation [GO:0090161]; late endosome to Golgi transport [GO:0034499]; microtubule anchoring [GO:0034453]; microtubule organizing center organization [GO:0031023]; protein localization to Golgi apparatus [GO:0034067]; protein targeting to lysosome [GO:0006622]; recycling endosome to Golgi transport [GO:0071955]; regulation of protein exit from endoplasmic reticulum [GO:0070861]; retrograde transport, endosome to Golgi [GO:0042147] GO:0005794; GO:0005802; GO:0005829; GO:0006622; GO:0016020; GO:0031023; GO:0034067; GO:0034453; GO:0034499; GO:0042147; GO:0042802; GO:0070861; GO:0071955; GO:0090161 14463 XM_044314141.1 105 65 25 39 111 P14381 2.63e-62 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 14464 XM_044314183.1 7 3 13 12 0 NA NA NA NA NA NA 14465 XM_044307735.1 2507 1204 1043 2816 1972 Q96L93 0 Kinesin-like protein KIF16B (Sorting nexin-23) Homo sapiens (Human) early endosome to late endosome transport [GO:0045022]; endoderm development [GO:0007492]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; formation of primary germ layer [GO:0001704]; Golgi to endosome transport [GO:0006895]; microtubule-based movement [GO:0007018]; receptor catabolic process [GO:0032801]; regulation of receptor recycling [GO:0001919] GO:0001704; GO:0001919; GO:0003777; GO:0005524; GO:0005547; GO:0005737; GO:0005768; GO:0005769; GO:0005819; GO:0005829; GO:0005871; GO:0005874; GO:0006895; GO:0007018; GO:0007173; GO:0007492; GO:0008017; GO:0008543; GO:0008574; GO:0016887; GO:0031901; GO:0032266; GO:0032801; GO:0043325; GO:0045022; GO:0080025 14466 XM_044307735.1 2507 1204 1043 2816 1972 Q96L93 5.91e-30 Kinesin-like protein KIF16B (Sorting nexin-23) Homo sapiens (Human) early endosome to late endosome transport [GO:0045022]; endoderm development [GO:0007492]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; formation of primary germ layer [GO:0001704]; Golgi to endosome transport [GO:0006895]; microtubule-based movement [GO:0007018]; receptor catabolic process [GO:0032801]; regulation of receptor recycling [GO:0001919] GO:0001704; GO:0001919; GO:0003777; GO:0005524; GO:0005547; GO:0005737; GO:0005768; GO:0005769; GO:0005819; GO:0005829; GO:0005871; GO:0005874; GO:0006895; GO:0007018; GO:0007173; GO:0007492; GO:0008017; GO:0008543; GO:0008574; GO:0016887; GO:0031901; GO:0032266; GO:0032801; GO:0043325; GO:0045022; GO:0080025 14467 XM_044322940.1 183 74 25 129 114 NA NA NA NA NA NA 14468 XM_044323999.1 233 45 0 127 33 NA NA NA NA NA NA 14469 XM_044325115.1 12 0 0 0 0 NA NA NA NA NA NA 14470 XM_029331065.2 1940 1057 1033 1426 2397 A7SFP1 0 Leucine-rich repeat protein soc-2 homolog Nematostella vectensis (Starlet sea anemone) positive regulation of Ras protein signal transduction [GO:0046579]; signal transduction [GO:0007165] GO:0007165; GO:0046579 14471 XM_044314404.1 120 0 0 81 34 Q99436 3.26e-35 Proteasome subunit beta type-7 (EC 3.4.25.1) (Macropain chain Z) (Multicatalytic endopeptidase complex chain Z) (Proteasome subunit Z) Homo sapiens (Human) proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] GO:0000502; GO:0004175; GO:0004298; GO:0005576; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005839; GO:0010498; GO:0016604; GO:0019774; GO:0034774; GO:0043161; GO:1904813 14472 XR_006396609.1 278 127 184 97 134 NA NA NA NA NA NA 14473 XM_029345043.2 923 374 0 972 289 NA NA NA NA NA NA 14474 XM_044325266.1 4 10 14 13 37 P10665 3.04e-44 Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (p90-RSK) Xenopus laevis (African clawed frog) intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468] GO:0000287; GO:0004674; GO:0005524; GO:0006468; GO:0035556; GO:0106310 14475 XM_029354600.2 1249 811 617 882 1013 D3YZP9 1.46e-86 Coiled-coil domain-containing protein 6 Mus musculus (Mouse) NA GO:0005829; GO:0005856; GO:0017124; GO:0042802 14476 XM_044320941.1 1804 1969 1167 1852 1754 NA NA NA NA NA NA 14477 XM_044323860.1 2 95 0 9 246 NA NA NA NA NA NA 14478 XM_029336246.2 151 123 196 220 584 Q6NUT3 8.58e-24 Major facilitator superfamily domain-containing protein 12 Homo sapiens (Human) carbohydrate transport [GO:0008643]; cysteine transmembrane transport [GO:1903712]; melanin biosynthetic process [GO:0042438]; negative regulation of melanin biosynthetic process [GO:0048022]; organic substance transport [GO:0071702]; pigment metabolic process involved in pigmentation [GO:0043474]; regulation of melanin biosynthetic process [GO:0048021] GO:0005764; GO:0005765; GO:0005770; GO:0005886; GO:0008643; GO:0015293; GO:0033162; GO:0033229; GO:0042438; GO:0042470; GO:0043474; GO:0048021; GO:0048022; GO:0071702; GO:1903712 14479 XM_044307247.1 20 2 29 59 10 Q92820 4.17e-91 Gamma-glutamyl hydrolase (EC 3.4.19.9) (Conjugase) (GH) (Gamma-Glu-X carboxypeptidase) Homo sapiens (Human) tetrahydrofolylpolyglutamate metabolic process [GO:0046900] GO:0005576; GO:0005615; GO:0005634; GO:0005773; GO:0008238; GO:0008242; GO:0034722; GO:0035578; GO:0035580; GO:0042470; GO:0046900; GO:0070062; GO:1904724 14480 XM_029325781.2 0 33 0 49 38 NA NA NA NA NA NA 14481 XM_044310129.1 47 0 0 0 0 NA NA NA NA NA NA 14482 XM_044317530.1 59 0 72 72 112 NA NA NA NA NA NA 14483 XM_029351656.2 9 0 0 0 0 P12256 1.8e-37 Penicillin acylase (EC 3.5.1.11) (Penicillin V amidase) (PVA) Lysinibacillus sphaericus (Bacillus sphaericus) response to antibiotic [GO:0046677] GO:0008953; GO:0046677 14484 XM_044317314.1 23 0 3 0 0 NA NA NA NA NA NA 14485 XM_044320553.1 625 445 228 264 198 NA NA NA NA NA NA 14486 XR_006395755.1 346 526 334 282 475 NA NA NA NA NA NA 14487 XM_029332720.2 1437 1744 1426 938 1185 Q9NUN7 1.21e-63 Alkaline ceramidase 3 (AlkCDase 3) (Alkaline CDase 3) (EC 3.5.1.-) (EC 3.5.1.23) (Alkaline dihydroceramidase SB89) (Alkaline phytoceramidase) (aPHC) Homo sapiens (Human) ceramide catabolic process [GO:0046514]; inflammatory response [GO:0006954]; myelination [GO:0042552]; phytosphingosine biosynthetic process [GO:0071602]; positive regulation of cell population proliferation [GO:0008284]; regulation of programmed cell death [GO:0043067]; sphingolipid biosynthetic process [GO:0030148]; sphingosine biosynthetic process [GO:0046512] GO:0000139; GO:0005509; GO:0005789; GO:0006954; GO:0008270; GO:0008284; GO:0016020; GO:0017040; GO:0030148; GO:0042552; GO:0043067; GO:0046512; GO:0046514; GO:0070774; GO:0071602; GO:0071633; GO:0102121 14488 XR_003824590.2 4 0 13 6 0 NA NA NA NA NA NA 14489 XM_029355873.2 7 0 3 58 48 Q96L50 8e-57 Leucine-rich repeat protein 1 (4-1BB-mediated-signaling molecule) (4-1BBlrr) (LRR-repeat protein 1) (LRR-1) (Peptidylprolyl isomerase-like 5) Homo sapiens (Human) protein ubiquitination [GO:0016567] GO:0005634; GO:0005829; GO:0016567 14490 XM_044319887.1 6140 8921 3210 4412 4392 Q9QZ85 2.89e-48 Interferon-inducible GTPase 1 (EC 3.6.5.-) Mus musculus (Mouse) cellular response to interferon-beta [GO:0035458]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; regulation of autophagy [GO:0010506]; response to bacterium [GO:0009617] GO:0003924; GO:0005525; GO:0005737; GO:0005789; GO:0006952; GO:0009617; GO:0010506; GO:0019003; GO:0019221; GO:0020005; GO:0031965; GO:0032580; GO:0035458; GO:0042802; GO:0042832; GO:0045087; GO:0050829 14491 XM_029356171.2 23 28 37 35 28 Q96A58 1.73e-37 Ras-related and estrogen-regulated growth inhibitor (EC 3.6.5.2) Homo sapiens (Human) negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; Ras protein signal transduction [GO:0007265]; response to hormone [GO:0009725]; small GTPase mediated signal transduction [GO:0007264] GO:0001650; GO:0003924; GO:0003925; GO:0005525; GO:0005634; GO:0005654; GO:0005829; GO:0005886; GO:0007264; GO:0007265; GO:0008285; GO:0009725; GO:0019003; GO:0030308; GO:0030331 14492 XM_029352404.2 209 20 36 122 212 Q9H267 1.39e-148 Vacuolar protein sorting-associated protein 33B (hVPS33B) Homo sapiens (Human) collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; endosome organization [GO:0007032]; intracellular protein transport [GO:0006886]; intracellular transport [GO:0046907]; lysosome localization [GO:0032418]; megakaryocyte development [GO:0035855]; melanosome localization [GO:0032400]; membrane fusion [GO:0061025]; peptidyl-lysine hydroxylation [GO:0017185]; phagosome-lysosome fusion [GO:0090385]; platelet alpha granule organization [GO:0070889]; protein transport [GO:0015031]; regulation of platelet aggregation [GO:0090330]; vesicle-mediated transport [GO:0016192] GO:0005737; GO:0005764; GO:0005765; GO:0005768; GO:0005770; GO:0005773; GO:0005794; GO:0005829; GO:0006886; GO:0007032; GO:0010008; GO:0015031; GO:0016192; GO:0017185; GO:0030136; GO:0030199; GO:0030897; GO:0031091; GO:0031901; GO:0031902; GO:0032400; GO:0032418; GO:0032963; GO:0033263; GO:0035855; GO:0044877; GO:0046907; GO:0048471; GO:0055037; GO:0061025; GO:0070889; GO:0090330; GO:0090385; GO:0099023 14493 XM_044312492.1 620 677 398 796 631 Q3MSQ8 9.55e-164 Probable ATP-dependent RNA helicase DDX4 (EC 3.6.4.13) (DEAD box protein 4) (Vasa homolog) Pelophylax lessonae (Pool frog) (Rana lessonae) DNA methylation involved in gamete generation [GO:0043046]; male meiosis I [GO:0007141]; male meiotic nuclear division [GO:0007140]; negative regulation of transposition [GO:0010529]; oogenesis [GO:0048477]; piRNA processing [GO:0034587]; spermatogenesis [GO:0007283] GO:0003676; GO:0003724; GO:0005524; GO:0007140; GO:0007141; GO:0007283; GO:0010529; GO:0016887; GO:0034587; GO:0043046; GO:0048477; GO:0071546; GO:0071547 14494 XM_044310349.1 3 1 1 0 6 NA NA NA NA NA NA 14495 XR_006396684.1 15 107 12 122 39 Q96DM1 2.96e-38 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 14496 XM_029340109.2 340 481 78 380 393 NA NA NA NA NA NA 14497 XR_003825634.2 27 50 30 1 60 NA NA NA NA NA NA 14498 XM_044315326.1 243 307 210 194 537 NA NA NA NA NA NA 14499 XM_044322182.1 3 14 0 14 3 Q96DM1 1.82e-51 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 14500 XM_044322182.1 3 14 0 14 3 Q96DM1 1.82e-51 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 14501 XR_006396039.1 15 8 9 14 79 NA NA NA NA NA NA 14502 XM_029335665.2 17 5 0 10 16 NA NA NA NA NA NA 14503 XM_029331147.2 775 466 430 510 574 Q8WXA3 6.55e-166 RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related) Homo sapiens (Human) regulation of endocytosis [GO:0030100] GO:0005634; GO:0005737; GO:0005768; GO:0017124; GO:0030100; GO:0046872 14504 XR_006394851.1 361 278 219 296 477 Q9WU01 1.89e-63 KH domain-containing, RNA-binding, signal transduction-associated protein 2 (Sam68-like mammalian protein 1) (SLM-1) (mSLM-1) Mus musculus (Mouse) mRNA processing [GO:0006397]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of mRNA splicing, via spliceosome [GO:0048024] GO:0000381; GO:0003729; GO:0005634; GO:0006397; GO:0008143; GO:0008266; GO:0017124; GO:0042169; GO:0048024 14505 XR_006396862.1 12 31 38 100 4 NA NA NA NA NA NA 14506 XM_044307428.1 531 199 1 349 70 Q9NR09 3.37e-176 Baculoviral IAP repeat-containing protein 6 (EC 2.3.2.27) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (RING-type E3 ubiquitin transferase BIRC6) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON) Homo sapiens (Human) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell population proliferation [GO:0008283]; labyrinthine layer development [GO:0060711]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of peptidase activity [GO:0010466]; positive regulation of cell population proliferation [GO:0008284]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell population proliferation [GO:0042127]; regulation of cytokinesis [GO:0032465]; regulation of endopeptidase activity [GO:0052548]; spongiotrophoblast layer development [GO:0060712] GO:0000922; GO:0004842; GO:0004869; GO:0005634; GO:0005768; GO:0005802; GO:0005815; GO:0005829; GO:0006468; GO:0006915; GO:0007049; GO:0008283; GO:0008284; GO:0010466; GO:0016020; GO:0016567; GO:0030496; GO:0032465; GO:0042127; GO:0043066; GO:0051301; GO:0052548; GO:0060711; GO:0060712; GO:0061631; GO:0090543; GO:2001237 14507 XM_044307428.1 531 199 1 349 70 Q9NR09 3.91e-91 Baculoviral IAP repeat-containing protein 6 (EC 2.3.2.27) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (RING-type E3 ubiquitin transferase BIRC6) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON) Homo sapiens (Human) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell population proliferation [GO:0008283]; labyrinthine layer development [GO:0060711]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of peptidase activity [GO:0010466]; positive regulation of cell population proliferation [GO:0008284]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell population proliferation [GO:0042127]; regulation of cytokinesis [GO:0032465]; regulation of endopeptidase activity [GO:0052548]; spongiotrophoblast layer development [GO:0060712] GO:0000922; GO:0004842; GO:0004869; GO:0005634; GO:0005768; GO:0005802; GO:0005815; GO:0005829; GO:0006468; GO:0006915; GO:0007049; GO:0008283; GO:0008284; GO:0010466; GO:0016020; GO:0016567; GO:0030496; GO:0032465; GO:0042127; GO:0043066; GO:0051301; GO:0052548; GO:0060711; GO:0060712; GO:0061631; GO:0090543; GO:2001237 14508 XM_044307428.1 531 199 1 349 70 Q9NR09 5.05e-73 Baculoviral IAP repeat-containing protein 6 (EC 2.3.2.27) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (RING-type E3 ubiquitin transferase BIRC6) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON) Homo sapiens (Human) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell population proliferation [GO:0008283]; labyrinthine layer development [GO:0060711]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of peptidase activity [GO:0010466]; positive regulation of cell population proliferation [GO:0008284]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell population proliferation [GO:0042127]; regulation of cytokinesis [GO:0032465]; regulation of endopeptidase activity [GO:0052548]; spongiotrophoblast layer development [GO:0060712] GO:0000922; GO:0004842; GO:0004869; GO:0005634; GO:0005768; GO:0005802; GO:0005815; GO:0005829; GO:0006468; GO:0006915; GO:0007049; GO:0008283; GO:0008284; GO:0010466; GO:0016020; GO:0016567; GO:0030496; GO:0032465; GO:0042127; GO:0043066; GO:0051301; GO:0052548; GO:0060711; GO:0060712; GO:0061631; GO:0090543; GO:2001237 14509 XM_044307428.1 531 199 1 349 70 Q9NR09 1.09e-56 Baculoviral IAP repeat-containing protein 6 (EC 2.3.2.27) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (RING-type E3 ubiquitin transferase BIRC6) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON) Homo sapiens (Human) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell population proliferation [GO:0008283]; labyrinthine layer development [GO:0060711]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of peptidase activity [GO:0010466]; positive regulation of cell population proliferation [GO:0008284]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell population proliferation [GO:0042127]; regulation of cytokinesis [GO:0032465]; regulation of endopeptidase activity [GO:0052548]; spongiotrophoblast layer development [GO:0060712] GO:0000922; GO:0004842; GO:0004869; GO:0005634; GO:0005768; GO:0005802; GO:0005815; GO:0005829; GO:0006468; GO:0006915; GO:0007049; GO:0008283; GO:0008284; GO:0010466; GO:0016020; GO:0016567; GO:0030496; GO:0032465; GO:0042127; GO:0043066; GO:0051301; GO:0052548; GO:0060711; GO:0060712; GO:0061631; GO:0090543; GO:2001237 14510 XM_044307428.1 531 199 1 349 70 Q9NR09 2.28e-33 Baculoviral IAP repeat-containing protein 6 (EC 2.3.2.27) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (RING-type E3 ubiquitin transferase BIRC6) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON) Homo sapiens (Human) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell population proliferation [GO:0008283]; labyrinthine layer development [GO:0060711]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of peptidase activity [GO:0010466]; positive regulation of cell population proliferation [GO:0008284]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell population proliferation [GO:0042127]; regulation of cytokinesis [GO:0032465]; regulation of endopeptidase activity [GO:0052548]; spongiotrophoblast layer development [GO:0060712] GO:0000922; GO:0004842; GO:0004869; GO:0005634; GO:0005768; GO:0005802; GO:0005815; GO:0005829; GO:0006468; GO:0006915; GO:0007049; GO:0008283; GO:0008284; GO:0010466; GO:0016020; GO:0016567; GO:0030496; GO:0032465; GO:0042127; GO:0043066; GO:0051301; GO:0052548; GO:0060711; GO:0060712; GO:0061631; GO:0090543; GO:2001237 14511 XM_044307428.1 531 199 1 349 70 Q9NR09 5.78e-32 Baculoviral IAP repeat-containing protein 6 (EC 2.3.2.27) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (RING-type E3 ubiquitin transferase BIRC6) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON) Homo sapiens (Human) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell population proliferation [GO:0008283]; labyrinthine layer development [GO:0060711]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of peptidase activity [GO:0010466]; positive regulation of cell population proliferation [GO:0008284]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell population proliferation [GO:0042127]; regulation of cytokinesis [GO:0032465]; regulation of endopeptidase activity [GO:0052548]; spongiotrophoblast layer development [GO:0060712] GO:0000922; GO:0004842; GO:0004869; GO:0005634; GO:0005768; GO:0005802; GO:0005815; GO:0005829; GO:0006468; GO:0006915; GO:0007049; GO:0008283; GO:0008284; GO:0010466; GO:0016020; GO:0016567; GO:0030496; GO:0032465; GO:0042127; GO:0043066; GO:0051301; GO:0052548; GO:0060711; GO:0060712; GO:0061631; GO:0090543; GO:2001237 14512 XM_044317214.1 206 111 119 261 154 P33268 1.55e-97 Cytochrome P450 3A8 (EC 1.14.14.1) (CYPIIIA8) (Cytochrome P-450-MK2) (Cytochrome P450-MKNF2) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0004497; GO:0005506; GO:0005789; GO:0020037; GO:0070330 14513 XM_044308803.1 26 0 46 0 38 NA NA NA NA NA NA 14514 XM_044318961.1 134 54 142 142 121 NA NA NA NA NA NA 14515 XM_044318488.1 43 37 34 449 61 NA NA NA NA NA NA 14516 XM_044328679.1 9 0 3 0 0 NA NA NA NA NA NA 14517 XM_044327994.1 368 455 270 372 298 Q0VCN3 4.5e-70 Intraflagellar transport protein 27 homolog (IFT27) (Putative GTP-binding protein RAY-like) (Rab-like protein 4) Bos taurus (Bovine) cell differentiation [GO:0030154]; intracellular protein transport [GO:0006886]; intraciliary transport [GO:0042073]; kidney development [GO:0001822]; smoothened signaling pathway [GO:0007224]; spermatogenesis [GO:0007283]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0001822; GO:0003924; GO:0005525; GO:0005737; GO:0005794; GO:0005929; GO:0006886; GO:0007224; GO:0007283; GO:0016192; GO:0030154; GO:0030992; GO:0036126; GO:0042073 14518 XR_006393241.1 7 12 53 19 47 NA NA NA NA NA NA 14519 XM_029337114.2 0 178 60 35 0 A2RV80 4.43e-70 GRAM domain-containing protein 4 Xenopus laevis (African clawed frog) apoptotic process [GO:0006915] GO:0005789; GO:0006915; GO:0031966 14520 XM_029332776.2 78 80 50 27 47 NA NA NA NA NA NA 14521 XM_044317467.1 7 0 0 23 41 NA NA NA NA NA NA 14522 XM_029345804.2 345 0 10 0 499 NA NA NA NA NA NA 14523 XM_029334639.2 203 374 143 795 287 A7RHG8 1.09e-153 Ribosome biogenesis protein WDR12 homolog Nematostella vectensis (Starlet sea anemone) rRNA processing [GO:0006364] GO:0005654; GO:0005730; GO:0006364 14524 XM_044316210.1 361 130 102 140 303 NA NA NA NA NA NA 14525 XM_044318241.1 95 59 49 168 88 Q9HAR2 3.98e-68 Adhesion G protein-coupled receptor L3 (Calcium-independent alpha-latrotoxin receptor 3) (CIRL-3) (Latrophilin-3) (Lectomedin-3) Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; brain development [GO:0007420]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; G protein-coupled receptor signaling pathway [GO:0007186]; neuron migration [GO:0001764]; synapse assembly [GO:0007416] GO:0001764; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007166; GO:0007186; GO:0007189; GO:0007416; GO:0007420; GO:0016020; GO:0030246; GO:0030424; GO:0098742; GO:0098978 14526 XM_029336501.2 0 40 3 4 0 P12256 5.06e-43 Penicillin acylase (EC 3.5.1.11) (Penicillin V amidase) (PVA) Lysinibacillus sphaericus (Bacillus sphaericus) response to antibiotic [GO:0046677] GO:0008953; GO:0046677 14527 XM_029338862.2 623 565 313 620 468 Q56A55 0 Mitochondrial potassium channel ATP-binding subunit (ATP-binding cassette sub-family B member 8, mitochondrial) (ABCB8) (Mitochondrial sulfonylurea-receptor) (MITOSUR) Danio rerio (Zebrafish) (Brachydanio rerio) potassium ion transmembrane transport [GO:0071805] GO:0005524; GO:0005739; GO:0005743; GO:0016887; GO:0062157; GO:0071805; GO:0140359 14528 XM_044325332.1 31 16 15 20 16 A6QLU6 7.13e-61 Adhesion G-protein coupled receptor D1 (G-protein coupled receptor 133) Bos taurus (Bovine) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0005886; GO:0007166; GO:0007186; GO:0007189 14529 XM_029327336.2 229 213 147 253 70 NA NA NA NA NA NA 14530 XM_029356008.2 23 52 95 137 135 Q14DL3 1.39e-48 Leucine-rich repeat and IQ domain-containing protein 3 (Leucine-rich repeat-containing protein 44) Mus musculus (Mouse) NA NA 14531 XM_029344722.2 376 115 107 177 0 Q5R2J4 7.28e-76 Protein APCDD1 (Adenomatosis polyposis coli down-regulated 1 protein homolog) (PsAPCDD1) Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis) negative regulation of Wnt signaling pathway [GO:0030178]; Wnt signaling pathway [GO:0016055] GO:0005615; GO:0005886; GO:0016055; GO:0017147; GO:0030178 14532 XM_029342844.2 35 22 43 27 222 G5E8K5 8.1e-80 Ankyrin-3 (ANK-3) (Ankyrin-G) Mus musculus (Mouse) anterograde axonal transport [GO:0008089]; axon development [GO:0061564]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; clustering of voltage-gated sodium channels [GO:0045162]; establishment of protein localization [GO:0045184]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in cell [GO:0032507]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of endocytosis [GO:0045806]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of action potential [GO:0045760]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; regulation of protein targeting [GO:1903533]; signal transduction [GO:0007165]; synapse organization [GO:0050808] GO:0000281; GO:0005200; GO:0005737; GO:0005764; GO:0005886; GO:0005923; GO:0007009; GO:0007165; GO:0007409; GO:0007411; GO:0007528; GO:0008089; GO:0008092; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014069; GO:0014704; GO:0014731; GO:0016020; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030424; GO:0030425; GO:0030507; GO:0030674; GO:0030951; GO:0031594; GO:0032507; GO:0033268; GO:0033270; GO:0034112; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045162; GO:0045184; GO:0045202; GO:0045211; GO:0045296; GO:0045760; GO:0045806; GO:0045838; GO:0050808; GO:0061564; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:0140031; GO:1900827; GO:1901224; GO:1902260; GO:1903533; GO:1904115; GO:2000651; GO:2001259 14533 XM_029342844.2 35 22 43 27 222 G5E8K5 8.65e-74 Ankyrin-3 (ANK-3) (Ankyrin-G) Mus musculus (Mouse) anterograde axonal transport [GO:0008089]; axon development [GO:0061564]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; clustering of voltage-gated sodium channels [GO:0045162]; establishment of protein localization [GO:0045184]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in cell [GO:0032507]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of endocytosis [GO:0045806]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of action potential [GO:0045760]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; regulation of protein targeting [GO:1903533]; signal transduction [GO:0007165]; synapse organization [GO:0050808] GO:0000281; GO:0005200; GO:0005737; GO:0005764; GO:0005886; GO:0005923; GO:0007009; GO:0007165; GO:0007409; GO:0007411; GO:0007528; GO:0008089; GO:0008092; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014069; GO:0014704; GO:0014731; GO:0016020; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030424; GO:0030425; GO:0030507; GO:0030674; GO:0030951; GO:0031594; GO:0032507; GO:0033268; GO:0033270; GO:0034112; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045162; GO:0045184; GO:0045202; GO:0045211; GO:0045296; GO:0045760; GO:0045806; GO:0045838; GO:0050808; GO:0061564; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:0140031; GO:1900827; GO:1901224; GO:1902260; GO:1903533; GO:1904115; GO:2000651; GO:2001259 14534 XM_029342844.2 35 22 43 27 222 G5E8K5 1.28e-73 Ankyrin-3 (ANK-3) (Ankyrin-G) Mus musculus (Mouse) anterograde axonal transport [GO:0008089]; axon development [GO:0061564]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; clustering of voltage-gated sodium channels [GO:0045162]; establishment of protein localization [GO:0045184]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in cell [GO:0032507]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of endocytosis [GO:0045806]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of action potential [GO:0045760]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; regulation of protein targeting [GO:1903533]; signal transduction [GO:0007165]; synapse organization [GO:0050808] GO:0000281; GO:0005200; GO:0005737; GO:0005764; GO:0005886; GO:0005923; GO:0007009; GO:0007165; GO:0007409; GO:0007411; GO:0007528; GO:0008089; GO:0008092; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014069; GO:0014704; GO:0014731; GO:0016020; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030424; GO:0030425; GO:0030507; GO:0030674; GO:0030951; GO:0031594; GO:0032507; GO:0033268; GO:0033270; GO:0034112; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045162; GO:0045184; GO:0045202; GO:0045211; GO:0045296; GO:0045760; GO:0045806; GO:0045838; GO:0050808; GO:0061564; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:0140031; GO:1900827; GO:1901224; GO:1902260; GO:1903533; GO:1904115; GO:2000651; GO:2001259 14535 XM_029342844.2 35 22 43 27 222 G5E8K5 6.07e-64 Ankyrin-3 (ANK-3) (Ankyrin-G) Mus musculus (Mouse) anterograde axonal transport [GO:0008089]; axon development [GO:0061564]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; clustering of voltage-gated sodium channels [GO:0045162]; establishment of protein localization [GO:0045184]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in cell [GO:0032507]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of endocytosis [GO:0045806]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of action potential [GO:0045760]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; regulation of protein targeting [GO:1903533]; signal transduction [GO:0007165]; synapse organization [GO:0050808] GO:0000281; GO:0005200; GO:0005737; GO:0005764; GO:0005886; GO:0005923; GO:0007009; GO:0007165; GO:0007409; GO:0007411; GO:0007528; GO:0008089; GO:0008092; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014069; GO:0014704; GO:0014731; GO:0016020; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030424; GO:0030425; GO:0030507; GO:0030674; GO:0030951; GO:0031594; GO:0032507; GO:0033268; GO:0033270; GO:0034112; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045162; GO:0045184; GO:0045202; GO:0045211; GO:0045296; GO:0045760; GO:0045806; GO:0045838; GO:0050808; GO:0061564; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:0140031; GO:1900827; GO:1901224; GO:1902260; GO:1903533; GO:1904115; GO:2000651; GO:2001259 14536 XM_029342844.2 35 22 43 27 222 G5E8K5 1.02e-60 Ankyrin-3 (ANK-3) (Ankyrin-G) Mus musculus (Mouse) anterograde axonal transport [GO:0008089]; axon development [GO:0061564]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; clustering of voltage-gated sodium channels [GO:0045162]; establishment of protein localization [GO:0045184]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in cell [GO:0032507]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of endocytosis [GO:0045806]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of action potential [GO:0045760]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; regulation of protein targeting [GO:1903533]; signal transduction [GO:0007165]; synapse organization [GO:0050808] GO:0000281; GO:0005200; GO:0005737; GO:0005764; GO:0005886; GO:0005923; GO:0007009; GO:0007165; GO:0007409; GO:0007411; GO:0007528; GO:0008089; GO:0008092; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014069; GO:0014704; GO:0014731; GO:0016020; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030424; GO:0030425; GO:0030507; GO:0030674; GO:0030951; GO:0031594; GO:0032507; GO:0033268; GO:0033270; GO:0034112; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045162; GO:0045184; GO:0045202; GO:0045211; GO:0045296; GO:0045760; GO:0045806; GO:0045838; GO:0050808; GO:0061564; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:0140031; GO:1900827; GO:1901224; GO:1902260; GO:1903533; GO:1904115; GO:2000651; GO:2001259 14537 XM_029342844.2 35 22 43 27 222 G5E8K5 2.45e-55 Ankyrin-3 (ANK-3) (Ankyrin-G) Mus musculus (Mouse) anterograde axonal transport [GO:0008089]; axon development [GO:0061564]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; clustering of voltage-gated sodium channels [GO:0045162]; establishment of protein localization [GO:0045184]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in cell [GO:0032507]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of endocytosis [GO:0045806]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of action potential [GO:0045760]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; regulation of protein targeting [GO:1903533]; signal transduction [GO:0007165]; synapse organization [GO:0050808] GO:0000281; GO:0005200; GO:0005737; GO:0005764; GO:0005886; GO:0005923; GO:0007009; GO:0007165; GO:0007409; GO:0007411; GO:0007528; GO:0008089; GO:0008092; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014069; GO:0014704; GO:0014731; GO:0016020; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030424; GO:0030425; GO:0030507; GO:0030674; GO:0030951; GO:0031594; GO:0032507; GO:0033268; GO:0033270; GO:0034112; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045162; GO:0045184; GO:0045202; GO:0045211; GO:0045296; GO:0045760; GO:0045806; GO:0045838; GO:0050808; GO:0061564; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:0140031; GO:1900827; GO:1901224; GO:1902260; GO:1903533; GO:1904115; GO:2000651; GO:2001259 14538 XM_044326203.1 102 32 43 216 83 NA NA NA NA NA NA 14539 XM_029342497.2 0 0 0 64 0 NA NA NA NA NA NA 14540 XM_044309674.1 172 51 167 142 123 Q55E58 5.28e-22 Probable serine/threonine-protein kinase pats1 (EC 2.7.11.1) (Protein associated with the transduction of signal 1) Dictyostelium discoideum (Social amoeba) cheating during chimeric sorocarp development [GO:0099139]; mitotic cytokinesis [GO:0000281]; phosphatidylinositol dephosphorylation [GO:0046856]; protein phosphorylation [GO:0006468] GO:0000281; GO:0004438; GO:0004674; GO:0004721; GO:0005524; GO:0005525; GO:0005829; GO:0006468; GO:0042641; GO:0046856; GO:0099139; GO:0106310 14541 XR_006392098.1 128 88 125 0 0 NA NA NA NA NA NA 14542 XR_006397831.1 0 53 15 48 149 NA NA NA NA NA NA 14543 XM_044306881.1 16 4 1 15 4 NA NA NA NA NA NA 14544 XM_044317953.1 28 7 39 158 87 Q9SZJ2 1.77e-36 Glycine-rich domain-containing protein 2 (AtGRDP2) Arabidopsis thaliana (Mouse-ear cress) auxin-activated signaling pathway [GO:0009734]; cellular response to osmotic stress [GO:0071470]; regulation of auxin mediated signaling pathway [GO:0010928]; regulation of photoperiodism, flowering [GO:2000028] GO:0009734; GO:0010928; GO:0071470; GO:2000028 14545 XM_044307039.1 157 64 89 66 82 Q5DU56 1.77e-37 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 14546 XM_044307039.1 157 64 89 66 82 Q5DU56 6.02e-34 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 14547 XM_044307039.1 157 64 89 66 82 Q5DU56 6.17e-34 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 14548 XM_044307039.1 157 64 89 66 82 Q5DU56 6.48e-28 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 14549 XM_044307039.1 157 64 89 66 82 Q5DU56 2.12e-22 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 14550 XM_044307039.1 157 64 89 66 82 Q5DU56 2.37e-22 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 14551 XM_029345520.2 337 67 178 196 440 Q9UJ83 0 2-hydroxyacyl-CoA lyase 1 (EC 4.1.2.63) (2-hydroxyphytanoyl-CoA lyase) (2-HPCL) (Phytanoyl-CoA 2-hydroxylase 2) Homo sapiens (Human) fatty acid alpha-oxidation [GO:0001561]; fatty acid metabolic process [GO:0006631]; methyl-branched fatty acid metabolic process [GO:0097089]; phytanic acid metabolic process [GO:1903512]; protein targeting to peroxisome [GO:0006625] GO:0000287; GO:0001561; GO:0005524; GO:0005654; GO:0005777; GO:0005782; GO:0005829; GO:0006625; GO:0006631; GO:0016830; GO:0030976; GO:0042802; GO:0043231; GO:0097089; GO:0106360; GO:0106376; GO:1903512 14552 XM_029344571.2 51 91 95 36 24 NA NA NA NA NA NA 14553 XM_044309889.1 0 4 2 0 8 NA NA NA NA NA NA 14554 XM_044327323.1 24 52 6 5 13 Q94K49 3.81e-31 Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1 (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) epigenetic regulation of gene expression [GO:0040029] GO:0003682; GO:0004518; GO:0005634; GO:0035098; GO:0035102; GO:0040029; GO:0046872 14555 XM_029331969.2 236 138 283 787 648 D3YXG0 3.51e-102 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 14556 XM_029331969.2 236 138 283 787 648 D3YXG0 4.34e-101 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 14557 XM_029331969.2 236 138 283 787 648 D3YXG0 7.72e-97 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 14558 XM_029331969.2 236 138 283 787 648 D3YXG0 7.25e-92 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 14559 XM_029331969.2 236 138 283 787 648 D3YXG0 4.89e-90 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 14560 XM_029331969.2 236 138 283 787 648 D3YXG0 1.68e-86 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 14561 XM_029331969.2 236 138 283 787 648 D3YXG0 3.75e-71 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 14562 XM_029331969.2 236 138 283 787 648 D3YXG0 6.03e-61 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 14563 XM_029331969.2 236 138 283 787 648 D3YXG0 1.37e-39 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 14564 XM_029331969.2 236 138 283 787 648 D3YXG0 2.39e-39 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 14565 XM_029331565.2 988 634 220 474 204 NA NA NA NA NA NA 14566 XM_029350794.1 733 543 451 582 306 Q640F2 6.99e-79 SHC SH2 domain-binding protein 1 homolog B Xenopus laevis (African clawed frog) fibroblast growth factor receptor signaling pathway [GO:0008543]; regulation of neural precursor cell proliferation [GO:2000177] GO:0005737; GO:0005819; GO:0008543; GO:0030496; GO:2000177 14567 XM_029335751.2 0 0 0 0 24 O43603 4.93e-21 Galanin receptor type 2 (GAL2-R) (GALR-2) Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell surface receptor signaling pathway [GO:0007166]; feeding behavior [GO:0007631]; galanin-activated signaling pathway [GO:0090663]; inositol phosphate metabolic process [GO:0043647]; learning or memory [GO:0007611]; muscle contraction [GO:0006936]; negative regulation of adenylate cyclase activity [GO:0007194]; neuron projection development [GO:0031175]; neuropeptide signaling pathway [GO:0007218]; phosphatidylinositol metabolic process [GO:0046488]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of large conductance calcium-activated potassium channel activity [GO:1902608]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0004966; GO:0005886; GO:0005929; GO:0006936; GO:0007166; GO:0007188; GO:0007189; GO:0007194; GO:0007200; GO:0007204; GO:0007218; GO:0007611; GO:0007631; GO:0008528; GO:0016020; GO:0017046; GO:0031175; GO:0042923; GO:0043647; GO:0045944; GO:0046488; GO:0090663; GO:1902608 14568 XM_044319611.1 0 0 0 0 9 B0BN95 1.02e-24 Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease) Rattus norvegicus (Rat) NA GO:0004518; GO:0005634; GO:0005737; GO:0046872 14569 XM_044324456.1 0 181 181 0 0 NA NA NA NA NA NA 14570 XM_044320360.1 0 0 0 17 27 NA NA NA NA NA NA 14571 XM_029333682.2 418 297 239 313 417 NA NA NA NA NA NA 14572 XM_044327734.1 3 10 18 48 15 NA NA NA NA NA NA 14573 XR_006396810.1 265 142 113 252 89 Q8CJG0 0 Protein argonaute-2 (Argonaute2) (mAgo2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (Piwi/argonaute family protein meIF2C2) (Protein slicer) Mus musculus (Mouse) cell differentiation [GO:0030154]; miRNA metabolic process [GO:0010586]; miRNA processing [GO:0035196]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; miRNA-mediated gene silencing by mRNA destabilization [GO:0035279]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; negative regulation of translational initiation [GO:0045947]; positive regulation of angiogenesis [GO:0045766]; positive regulation of gene expression [GO:0010628]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of trophoblast cell migration [GO:1901165]; post-embryonic development [GO:0009791]; pre-miRNA processing [GO:0031054]; RISC complex assembly [GO:0070922]; RNA secondary structure unwinding [GO:0010501]; RNA-mediated gene silencing [GO:0031047]; siRNA processing [GO:0030422]; siRNA-mediated gene silencing by mRNA destabilization [GO:0090625] GO:0000340; GO:0000932; GO:0000993; GO:0001046; GO:0003723; GO:0003725; GO:0003727; GO:0003729; GO:0004521; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0005844; GO:0005845; GO:0008022; GO:0009791; GO:0010501; GO:0010586; GO:0010628; GO:0016442; GO:0030154; GO:0030422; GO:0030425; GO:0031047; GO:0031054; GO:0035196; GO:0035197; GO:0035198; GO:0035278; GO:0035279; GO:0036464; GO:0042985; GO:0045766; GO:0045944; GO:0045947; GO:0046872; GO:0060213; GO:0070062; GO:0070551; GO:0070578; GO:0070922; GO:0090624; GO:0090625; GO:0098808; GO:1900153; GO:1901165; GO:1990904 14574 XR_006397155.1 0 0 0 16 5 NA NA NA NA NA NA 14575 XM_044325391.1 0 0 0 86 172 Q5R971 3.75e-158 Delta-aminolevulinic acid dehydratase (ALADH) (EC 4.2.1.24) (Porphobilinogen synthase) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782] GO:0004655; GO:0006782; GO:0006783; GO:0008270 14576 XM_044311637.1 0 0 0 11 2 NA NA NA NA NA NA 14577 XM_029336519.2 57 14 34 90 92 NA NA NA NA NA NA 14578 XM_044315772.1 149 7 0 38 18 NA NA NA NA NA NA 14579 XM_044307524.1 5572 3724 2788 4935 4595 Q13308 4.81e-162 Inactive tyrosine-protein kinase 7 (Colon carcinoma kinase 4) (CCK-4) (Protein-tyrosine kinase 7) (Pseudo tyrosine kinase receptor 7) (Tyrosine-protein kinase-like 7) Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; axis elongation [GO:0003401]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to retinoic acid [GO:0071300]; cochlea morphogenesis [GO:0090103]; convergent extension [GO:0060026]; coronary vasculature development [GO:0060976]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of planar polarity [GO:0001736]; kidney development [GO:0001822]; lung-associated mesenchyme development [GO:0060484]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of neuron projection development [GO:0010976]; protein phosphorylation [GO:0006468]; regulation of canonical Wnt signaling pathway [GO:0060828]; signal transduction [GO:0007165]; ventricular septum development [GO:0003281]; wound healing [GO:0042060] GO:0001736; GO:0001822; GO:0003281; GO:0003401; GO:0004672; GO:0005524; GO:0005886; GO:0005911; GO:0005925; GO:0006468; GO:0007155; GO:0007165; GO:0010976; GO:0016477; GO:0031532; GO:0042060; GO:0045198; GO:0050839; GO:0060026; GO:0060484; GO:0060828; GO:0060976; GO:0071300; GO:0090103; GO:0090179; GO:0090263; GO:1904929 14580 XM_044307524.1 5572 3724 2788 4935 4595 Q13308 1.14e-80 Inactive tyrosine-protein kinase 7 (Colon carcinoma kinase 4) (CCK-4) (Protein-tyrosine kinase 7) (Pseudo tyrosine kinase receptor 7) (Tyrosine-protein kinase-like 7) Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; axis elongation [GO:0003401]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to retinoic acid [GO:0071300]; cochlea morphogenesis [GO:0090103]; convergent extension [GO:0060026]; coronary vasculature development [GO:0060976]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of planar polarity [GO:0001736]; kidney development [GO:0001822]; lung-associated mesenchyme development [GO:0060484]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of neuron projection development [GO:0010976]; protein phosphorylation [GO:0006468]; regulation of canonical Wnt signaling pathway [GO:0060828]; signal transduction [GO:0007165]; ventricular septum development [GO:0003281]; wound healing [GO:0042060] GO:0001736; GO:0001822; GO:0003281; GO:0003401; GO:0004672; GO:0005524; GO:0005886; GO:0005911; GO:0005925; GO:0006468; GO:0007155; GO:0007165; GO:0010976; GO:0016477; GO:0031532; GO:0042060; GO:0045198; GO:0050839; GO:0060026; GO:0060484; GO:0060828; GO:0060976; GO:0071300; GO:0090103; GO:0090179; GO:0090263; GO:1904929 14581 XM_029335044.2 0 78 0 35 138 NA NA NA NA NA NA 14582 XM_029323550.2 1465 514 517 1135 1464 Q80TT2 1.08e-156 BAI1-associated protein 3 (BAP3) (Brain-specific angiogenesis inhibitor I-associated protein 3) (Baiap3) Mus musculus (Mouse) dense core granule maturation [GO:1990502]; exocytosis [GO:0006887]; G protein-coupled receptor signaling pathway [GO:0007186]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of neurotransmitter secretion [GO:0001956]; regulation of behavior [GO:0050795]; regulation of dense core granule exocytosis [GO:1905413]; regulation of synaptic transmission, GABAergic [GO:0032228]; retrograde transport, endosome to Golgi [GO:0042147] GO:0000149; GO:0001956; GO:0005509; GO:0005543; GO:0005829; GO:0005886; GO:0006887; GO:0007186; GO:0019905; GO:0031902; GO:0032228; GO:0032588; GO:0035774; GO:0042147; GO:0050795; GO:0050804; GO:0055038; GO:0098793; GO:0098982; GO:0099503; GO:1905413; GO:1990502 14583 XR_003825490.2 90 11 27 103 11 NA NA NA NA NA NA 14584 XM_029358720.2 129 36 0 130 181 Q9GYZ0 0 Kinesin-like protein KIF15 (Kinesin-related protein KRP180) Strongylocentrotus purpuratus (Purple sea urchin) microtubule-based movement [GO:0007018]; regulation of mitotic spindle assembly [GO:1901673] GO:0003777; GO:0005524; GO:0005737; GO:0005819; GO:0005871; GO:0005874; GO:0007018; GO:0008017; GO:0016887; GO:1901673 14585 XM_044319154.1 261 30 23 98 71 NA NA NA NA NA NA 14586 XM_029329288.2 1587 812 688 1559 1003 Q9I9H8 0 Apoptotic protease-activating factor 1 (APAF-1) Danio rerio (Zebrafish) (Brachydanio rerio) anatomical structure development [GO:0048856]; apoptotic signaling pathway [GO:0097190]; regulation of apoptotic process [GO:0042981] GO:0005524; GO:0042981; GO:0043293; GO:0043531; GO:0048856; GO:0097190 14587 XM_029343120.2 28 42 0 0 0 Q9Z351 4.01e-56 Potassium voltage-gated channel subfamily KQT member 2 (KQT-like 2) (Potassium channel subunit alpha KvLQT2) (Voltage-gated potassium channel subunit Kv7.2) Mus musculus (Mouse) potassium ion transmembrane transport [GO:0071805]; regulation of ion transmembrane transport [GO:0034765]; transmission of nerve impulse [GO:0019226] GO:0005244; GO:0005249; GO:0005251; GO:0005516; GO:0005886; GO:0008076; GO:0009986; GO:0016020; GO:0019226; GO:0030506; GO:0032991; GO:0033268; GO:0034765; GO:0043194; GO:0047485; GO:0071805 14588 XM_029330293.2 40 15 12 18 3 Q9VBW3 2.42e-62 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 14589 XR_006394326.1 78 0 0 0 0 NA NA NA NA NA NA 14590 XM_029329577.2 0 40 0 52 23 A4IGL7 3.84e-89 Peroxidasin (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0005576; GO:0005604; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0031012; GO:0042744; GO:0046872; GO:0051260; GO:0070207; GO:0070831; GO:0071711; GO:0140825 14591 XM_044317032.1 677 237 145 320 58 A5PK71 2.08e-118 Parkin coregulated gene protein Bos taurus (Bovine) negative regulation of cell death [GO:0060548]; protein localization [GO:0008104]; spermatid development [GO:0007286] GO:0001664; GO:0002177; GO:0003779; GO:0005829; GO:0005879; GO:0007286; GO:0008104; GO:0030544; GO:0031625; GO:0031982; GO:0043005; GO:0043014; GO:0044297; GO:0048487; GO:0051087; GO:0051879; GO:0060548; GO:0097225 14592 XM_029333928.2 3047 2570 1629 3208 3300 Q8N8S7 8.02e-45 Protein enabled homolog Homo sapiens (Human) actin polymerization or depolymerization [GO:0008154]; actin polymerization-dependent cell motility [GO:0070358]; axon guidance [GO:0007411] GO:0003779; GO:0005522; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0007411; GO:0008154; GO:0017124; GO:0030027; GO:0030054; GO:0030175; GO:0045202; GO:0050699; GO:0070358 14593 XM_044311037.1 11 22 7 16 39 NA NA NA NA NA NA 14594 XM_029344899.2 21 18 9 128 79 NA NA NA NA NA NA 14595 XM_029340231.2 158 195 67 112 326 F6NXI9 2.14e-118 NA NA NA NA 14596 XM_044309253.1 16 0 3 4 9 NA NA NA NA NA NA 14597 XM_044320480.1 1 2 8 2 0 NA NA NA NA NA NA 14598 XM_029358368.2 132 0 47 96 115 Q28G26 0 Phosphatidylinositol 4-kinase type 2-beta (EC 2.7.1.67) (Phosphatidylinositol 4-kinase type II-beta) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) phosphatidylinositol phosphate biosynthetic process [GO:0046854]; phosphorylation [GO:0016310] GO:0000139; GO:0004430; GO:0005524; GO:0005789; GO:0005829; GO:0005886; GO:0016310; GO:0031901; GO:0046854 14599 XM_044324693.1 381 1767 961 5368 5094 D3YXG0 3.16e-45 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 14600 XM_044324693.1 381 1767 961 5368 5094 D3YXG0 4.91e-43 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 14601 XM_044324693.1 381 1767 961 5368 5094 D3YXG0 3.65e-42 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 14602 XM_044324693.1 381 1767 961 5368 5094 D3YXG0 1.31e-39 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 14603 XM_044324693.1 381 1767 961 5368 5094 D3YXG0 5.97e-39 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 14604 XM_044324693.1 381 1767 961 5368 5094 D3YXG0 1.35e-38 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 14605 XM_044324693.1 381 1767 961 5368 5094 D3YXG0 1.62e-38 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 14606 XM_044324693.1 381 1767 961 5368 5094 D3YXG0 1.55e-37 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 14607 XM_044324693.1 381 1767 961 5368 5094 D3YXG0 1.78e-37 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 14608 XM_044324693.1 381 1767 961 5368 5094 D3YXG0 5.58e-36 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 14609 XM_044324693.1 381 1767 961 5368 5094 D3YXG0 3.5e-35 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 14610 XM_044324693.1 381 1767 961 5368 5094 D3YXG0 7.31e-35 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 14611 XM_044324693.1 381 1767 961 5368 5094 D3YXG0 4.13e-34 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 14612 XM_044324693.1 381 1767 961 5368 5094 D3YXG0 4.5e-25 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 14613 XM_044320947.1 24 56 68 129 71 NA NA NA NA NA NA 14614 XM_044321709.1 0 0 0 54 0 A4D0V7 9.65e-99 Cadherin-like and PC-esterase domain-containing protein 1 Homo sapiens (Human) NA GO:0005783 14615 XM_044321310.1 14 7 30 28 44 NA NA NA NA NA NA 14616 XM_044321769.1 0 96 71 0 0 Q91740 1.11e-21 Fibronectin (FN) Xenopus laevis (African clawed frog) acute-phase response [GO:0006953]; cell adhesion [GO:0007155]; regulation of cell shape [GO:0008360] GO:0005576; GO:0006953; GO:0007155; GO:0008201; GO:0008360 14617 XM_044316721.1 261 646 389 295 11 P14207 7.05e-36 Folate receptor beta (FR-beta) (Folate receptor 2) (Folate receptor, fetal/placental) (Placental folate-binding protein) (FBP) Homo sapiens (Human) cell adhesion [GO:0007155]; folic acid transport [GO:0015884]; fusion of sperm to egg plasma membrane involved in single fertilization [GO:0007342]; inflammatory response [GO:0006954]; positive regulation of cell population proliferation [GO:0008284]; sperm-egg recognition [GO:0035036] GO:0005542; GO:0005576; GO:0005886; GO:0006954; GO:0007155; GO:0007342; GO:0008284; GO:0009897; GO:0009986; GO:0015884; GO:0035036; GO:0038023; GO:0061714 14618 XM_044318697.1 0 95 0 0 0 NA NA NA NA NA NA 14619 XM_029345455.2 1296 1463 560 1908 1795 Q9UG63 0 ATP-binding cassette sub-family F member 2 (Iron-inhibited ABC transporter 2) Homo sapiens (Human) NA GO:0005524; GO:0016020; GO:0016887 14620 XM_029345060.2 64 0 0 0 0 NA NA NA NA NA NA 14621 XM_044306827.1 376 163 88 171 516 Q3B8R1 3.58e-78 Endoplasmic reticulum membrane-associated RNA degradation protein (ER membrane-associated RNA degradation protein) Rattus norvegicus (Rat) NA GO:0005789 14622 XM_044317592.1 15 7 0 116 0 Q96AY4 2.27e-67 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14623 XM_044317592.1 15 7 0 116 0 Q96AY4 1.16e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14624 XM_044317592.1 15 7 0 116 0 Q96AY4 2.96e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14625 XM_044317592.1 15 7 0 116 0 Q96AY4 8.48e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14626 XM_044317592.1 15 7 0 116 0 Q96AY4 1.01e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14627 XM_044317592.1 15 7 0 116 0 Q96AY4 1.13e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14628 XM_044317592.1 15 7 0 116 0 Q96AY4 4.46e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14629 XM_044317592.1 15 7 0 116 0 Q96AY4 2.11e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14630 XM_044317592.1 15 7 0 116 0 Q96AY4 2.17e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14631 XM_044315424.1 280 34 31 113 65 NA NA NA NA NA NA 14632 XM_029331273.2 520 428 283 301 497 Q9BWD1 3.68e-163 Acetyl-CoA acetyltransferase, cytosolic (EC 2.3.1.9) (Acetyl-CoA transferase-like protein) (Cytosolic acetoacetyl-CoA thiolase) Homo sapiens (Human) fatty acid beta-oxidation [GO:0006635]; lipid metabolic process [GO:0006629] GO:0003985; GO:0005737; GO:0005739; GO:0005829; GO:0006629; GO:0006635; GO:0070062 14633 XR_006394658.1 33 0 7 22 80 NA NA NA NA NA NA 14634 XM_044308429.1 0 0 12 0 33 NA NA NA NA NA NA 14635 XM_029344041.2 0 0 0 0 37 NA NA NA NA NA NA 14636 XR_006391813.1 196 95 192 99 528 NA NA NA NA NA NA 14637 XM_029338131.2 677 601 147 533 682 Q5RBN8 1.67e-101 Protein lin-54 homolog Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cell cycle [GO:0007049] GO:0003677; GO:0005634; GO:0007049; GO:0046872 14638 XM_029332791.2 488 276 379 468 193 NA NA NA NA NA NA 14639 XM_044316823.1 865 469 369 547 447 Q14166 9.86e-180 Tubulin--tyrosine ligase-like protein 12 (Inactive tubulin--tyrosine ligase-like protein 12) Homo sapiens (Human) innate immune response [GO:0045087]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; protein modification process [GO:0036211]; regulation of mitotic cell cycle [GO:0007346] GO:0005524; GO:0005634; GO:0005737; GO:0005815; GO:0005819; GO:0007346; GO:0015631; GO:0030496; GO:0036211; GO:0045087; GO:0060339; GO:1990889 14640 XR_006395150.1 46 14 7 0 37 NA NA NA NA NA NA 14641 XM_029350723.2 0 11 0 0 0 NA NA NA NA NA NA 14642 XM_029349521.2 6523 6419 4605 8502 6857 NA NA NA NA NA NA 14643 XM_029334721.2 60 0 0 41 25 P62997 1.07e-45 Transformer-2 protein homolog beta (TRA-2 beta) (TRA2-beta) (RA301) (Splicing factor, arginine/serine-rich 10) (Transformer-2 protein homolog B) Rattus norvegicus (Rat) cellular response to glucose stimulus [GO:0071333]; cerebral cortex regionalization [GO:0021796]; embryonic brain development [GO:1990403]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of RNA splicing [GO:0043484]; response to reactive oxygen species [GO:0000302] GO:0000302; GO:0000381; GO:0000398; GO:0001673; GO:0003723; GO:0003729; GO:0005634; GO:0005637; GO:0005681; GO:0019904; GO:0021796; GO:0032991; GO:0036002; GO:0042802; GO:0043484; GO:0048026; GO:0048471; GO:0071333; GO:1990403 14644 XM_029342312.2 19 13 2 13 10 NA NA NA NA NA NA 14645 XM_044316543.1 5 7 3 12 1 Q09575 2.46e-37 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 14646 XR_006392005.1 25 64 95 215 53 NA NA NA NA NA NA 14647 XR_006393455.1 0 0 0 8 0 NA NA NA NA NA NA 14648 XM_029346685.2 1007 169 232 811 683 NA NA NA NA NA NA 14649 XM_044316128.1 116 39 37 45 40 NA NA NA NA NA NA 14650 XM_044309008.1 165 0 24 37 78 NA NA NA NA NA NA 14651 XM_044318654.1 121 0 76 0 67 O75899 1.01e-71 Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51) (HG20) Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway [GO:0007186]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; neuron-glial cell signaling [GO:0150099]; synaptic transmission, GABAergic [GO:0051932] GO:0004888; GO:0004965; GO:0005737; GO:0005886; GO:0007186; GO:0007193; GO:0007194; GO:0007214; GO:0007268; GO:0038039; GO:0043005; GO:0045211; GO:0046982; GO:0051932; GO:0150099; GO:1902710; GO:1902712 14652 XM_044320800.1 1908 7950 367 1565 740 NA NA NA NA NA NA 14653 XM_044314102.1 158 89 73 95 88 Q9WTK3 1.88e-94 Glycosylphosphatidylinositol anchor attachment 1 protein (GPI anchor attachment protein 1) (GAA1 protein homolog) (mGAA1) Mus musculus (Mouse) attachment of GPI anchor to protein [GO:0016255]; GPI anchor biosynthetic process [GO:0006506]; protein-containing complex assembly [GO:0065003] GO:0003923; GO:0005739; GO:0005783; GO:0005813; GO:0005829; GO:0005886; GO:0006506; GO:0016020; GO:0016255; GO:0034235; GO:0042765; GO:0065003 14654 XM_029330369.2 28 0 13 32 153 O42357 1.04e-24 Retinal homeobox protein Rx2 Danio rerio (Zebrafish) (Brachydanio rerio) camera-type eye photoreceptor cell differentiation [GO:0060219]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0045944; GO:0060219 14655 XR_003824846.2 12 1 4 7 0 NA NA NA NA NA NA 14656 XR_006398181.1 1535 1250 679 457 1065 NA NA NA NA NA NA 14657 XM_044306914.1 0 3 5 10 5 NA NA NA NA NA NA 14658 XM_029350812.2 80 134 77 161 139 Q91175 4.76e-37 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (MAR1) Oryzias latipes (Japanese rice fish) (Japanese killifish) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of vasoconstriction [GO:0045907] GO:0001996; GO:0004930; GO:0004937; GO:0005886; GO:0007200; GO:0007204; GO:0007267; GO:0043410; GO:0045907; GO:0071880 14659 XM_029333815.2 1010 865 500 818 1032 D3YXG0 9.44e-44 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 14660 XM_029333815.2 1010 865 500 818 1032 D3YXG0 4.56e-40 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 14661 XM_029333815.2 1010 865 500 818 1032 D3YXG0 2.6e-39 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 14662 XM_029355342.2 423 934 63 244 80 NA NA NA NA NA NA 14663 XM_044327012.1 93 0 0 0 0 NA NA NA NA NA NA 14664 XM_029354150.2 0 0 16 0 0 Q6DHN0 9.26e-31 Transmembrane protein 53 Danio rerio (Zebrafish) (Brachydanio rerio) negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of ossification [GO:0030279]; negative regulation of osteoblast differentiation [GO:0045668]; regulation of nucleocytoplasmic transport [GO:0046822] GO:0005640; GO:0030279; GO:0030514; GO:0031965; GO:0045668; GO:0046822 14665 XR_003824963.2 23 3 44 0 0 NA NA NA NA NA NA 14666 XR_006391352.1 217 156 383 771 501 NA NA NA NA NA NA 14667 XR_006393696.1 23 53 57 54 62 NA NA NA NA NA NA 14668 XM_029348371.2 1596 1583 1131 1605 2372 Q9DGQ7 5.98e-125 Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37) Tetraodon fluviatilis (Green pufferfish) (Chelonodon fluviatilis) NA GO:0005737; GO:0019901 14669 XR_006391683.1 282 141 224 261 137 NA NA NA NA NA NA 14670 XM_029328774.2 78 51 87 100 190 P51471 1.3e-26 Blue-sensitive opsin (Blue photoreceptor pigment) (RH2 opsin) Anolis carolinensis (Green anole) (American chameleon) absorption of visible light [GO:0016038]; cellular response to light stimulus [GO:0071482]; G protein-coupled receptor signaling pathway [GO:0007186]; light absorption [GO:0016037]; phototransduction [GO:0007602]; visual perception [GO:0007601] GO:0001750; GO:0005886; GO:0007186; GO:0007601; GO:0007602; GO:0008020; GO:0016037; GO:0016038; GO:0071482 14671 XM_029350464.2 0 0 45 119 38 Q9H0Z9 3.13e-29 RNA-binding protein 38 (CLL-associated antigen KW-5) (HSRNASEB) (RNA-binding motif protein 38) (RNA-binding region-containing protein 1) (ssDNA-binding protein SEB4) Homo sapiens (Human) 3'-UTR-mediated mRNA stabilization [GO:0070935]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; mRNA processing [GO:0006397]; mRNA stabilization [GO:0048255]; negative regulation of cell population proliferation [GO:0008285]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of cell cycle [GO:0051726]; regulation of myotube differentiation [GO:0010830]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380] GO:0000381; GO:0003723; GO:0003729; GO:0003730; GO:0005634; GO:0005829; GO:0006397; GO:0006977; GO:0006978; GO:0007049; GO:0008285; GO:0008380; GO:0010830; GO:0030154; GO:0043484; GO:0048255; GO:0051726; GO:0070935 14672 XR_006392964.1 41 2 25 5 151 NA NA NA NA NA NA 14673 XM_044328932.1 4903 2706 2425 5194 5151 C3YWU0 0 Alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucoside fucohydrolase) Branchiostoma floridae (Florida lancelet) (Amphioxus) fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139] GO:0004560; GO:0005576; GO:0005764; GO:0006004; GO:0016139 14674 XM_044310126.1 0 9 0 0 0 NA NA NA NA NA NA 14675 XM_044321239.1 12 13 14 5 19 Q09575 1.67e-29 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 14676 XM_029338370.2 197 341 362 0 0 Q80U12 0 Small G protein signaling modulator 2 (RUN and TBC1 domain-containing protein 1) Mus musculus (Mouse) activation of GTPase activity [GO:0090630]; late endosome to Golgi transport [GO:0034499]; positive regulation of GTPase activity [GO:0043547] GO:0005096; GO:0005737; GO:0031267; GO:0034499; GO:0042470; GO:0043547; GO:0090630 14677 XM_029339895.2 552 474 405 653 0 A8MW92 1.96e-30 PHD finger protein 20-like protein 1 Homo sapiens (Human) histone acetylation [GO:0016573]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein catabolic process [GO:0042177]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0005634; GO:0006357; GO:0016573; GO:0032435; GO:0042177; GO:0044545; GO:0046872; GO:0140034 14678 XM_029339895.2 552 474 405 653 0 A8MW92 3.93e-24 PHD finger protein 20-like protein 1 Homo sapiens (Human) histone acetylation [GO:0016573]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein catabolic process [GO:0042177]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0005634; GO:0006357; GO:0016573; GO:0032435; GO:0042177; GO:0044545; GO:0046872; GO:0140034 14679 XM_044328317.1 135 127 62 57 101 Q9Y383 4.39e-63 Putative RNA-binding protein Luc7-like 2 Homo sapiens (Human) mRNA splice site selection [GO:0006376] GO:0003723; GO:0003729; GO:0005685; GO:0006376; GO:0016607; GO:0019899; GO:0071004 14680 XM_044328317.1 135 127 62 57 101 Q9Y383 4.39e-63 Putative RNA-binding protein Luc7-like 2 Homo sapiens (Human) mRNA splice site selection [GO:0006376] GO:0003723; GO:0003729; GO:0005685; GO:0006376; GO:0016607; GO:0019899; GO:0071004 14681 XM_044328317.1 135 127 62 57 101 Q9Y383 4.39e-63 Putative RNA-binding protein Luc7-like 2 Homo sapiens (Human) mRNA splice site selection [GO:0006376] GO:0003723; GO:0003729; GO:0005685; GO:0006376; GO:0016607; GO:0019899; GO:0071004 14682 XM_029342691.2 330 385 297 395 522 Q9Z321 0 DNA topoisomerase 3-beta-1 (EC 5.6.2.1) (DNA topoisomerase III beta-1) Mus musculus (Mouse) chromosome segregation [GO:0007059]; DNA topological change [GO:0006265] GO:0000793; GO:0003677; GO:0003916; GO:0003917; GO:0005634; GO:0006265; GO:0007059; GO:0140225 14683 XM_029348374.2 25 12 22 47 74 NA NA NA NA NA NA 14684 XR_006393860.1 0 0 0 0 18 NA NA NA NA NA NA 14685 XM_029333615.2 859 784 376 600 284 A2VE55 5.49e-128 UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter (Solute carrier family 35 member D2) Bos taurus (Bovine) carbohydrate transport [GO:0008643] GO:0000139; GO:0005461; GO:0005462; GO:0005463; GO:0005794; GO:0008643; GO:0015297 14686 XM_044317399.1 0 36 0 2 280 F1MNN4 5.17e-68 F-box/WD repeat-containing protein 7 (F-box and WD-40 domain-containing protein 7) Bos taurus (Bovine) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; lung development [GO:0030324]; negative regulation of gene expression [GO:0010629]; negative regulation of osteoclast development [GO:2001205]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; Notch signaling pathway [GO:0007219]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903378]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein destabilization [GO:0031648]; protein K63-linked ubiquitination [GO:0070534]; protein stabilization [GO:0050821]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of cell migration involved in sprouting angiogenesis [GO:0090049]; regulation of circadian rhythm [GO:0042752]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; sister chromatid cohesion [GO:0007062]; vasculogenesis [GO:0001570] GO:0001570; GO:0005654; GO:0005694; GO:0005730; GO:0005739; GO:0005783; GO:0006281; GO:0006886; GO:0006888; GO:0006890; GO:0006891; GO:0006974; GO:0007062; GO:0007219; GO:0010629; GO:0019005; GO:0030126; GO:0030324; GO:0030332; GO:0031146; GO:0031625; GO:0031648; GO:0042752; GO:0042802; GO:0045741; GO:0048471; GO:0050816; GO:0050821; GO:0051443; GO:0070374; GO:0070534; GO:0090049; GO:0097027; GO:1901800; GO:1903026; GO:1903146; GO:1903378; GO:1903955; GO:1990452; GO:1990756; GO:2000060; GO:2001205 14687 XM_044314680.1 0 121 0 0 0 NA NA NA NA NA NA 14688 XR_006396679.1 0 0 16 0 0 NA NA NA NA NA NA 14689 XR_006394180.1 0 0 39 61 70 NA NA NA NA NA NA 14690 XM_029350713.2 372 29 221 98 578 A0A096X8J7 0 NA NA NA NA 14691 XM_044327493.1 1179 350 557 204 156 NA NA NA NA NA NA 14692 XM_044308719.1 0 42 0 0 0 NA NA NA NA NA NA 14693 XM_044316555.1 0 0 0 0 6 NA NA NA NA NA NA 14694 XR_006392448.1 91 17 86 91 57 NA NA NA NA NA NA 14695 XM_044319897.1 81 21 104 61 113 Q54PH5 7.5e-62 Pre-mRNA-splicing factor cwc2 Dictyostelium discoideum (Social amoeba) mRNA cis splicing, via spliceosome [GO:0045292]; positive regulation of cell cycle [GO:0045787]; positive regulation of RNA splicing [GO:0033120]; spliceosomal snRNP assembly [GO:0000387] GO:0000387; GO:0000974; GO:0005634; GO:0005681; GO:0017070; GO:0033120; GO:0036002; GO:0045292; GO:0045787; GO:0046872; GO:0071006; GO:0071007 14696 XM_029338377.2 110 42 14 74 14 NA NA NA NA NA NA 14697 XM_044324248.1 0 3 0 47 28 O35923 3.56e-129 Breast cancer type 2 susceptibility protein homolog (Fanconi anemia group D1 protein homolog) Rattus norvegicus (Rat) brain development [GO:0007420]; cell population proliferation [GO:0008283]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to ionizing radiation [GO:0071479]; cellular senescence [GO:0090398]; centrosome duplication [GO:0051298]; chordate embryonic development [GO:0043009]; chromosome organization [GO:0051276]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; establishment of protein localization to telomere [GO:0070200]; female gonad development [GO:0008585]; hematopoietic stem cell proliferation [GO:0071425]; hemopoiesis [GO:0030097]; histone H3 acetylation [GO:0043966]; histone H4 acetylation [GO:0043967]; homologous chromosome orientation involved in meiotic metaphase I plate congression [GO:0031619]; inner cell mass cell proliferation [GO:0001833]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; male meiosis I [GO:0007141]; mammary gland development [GO:0030879]; mitotic recombination-dependent replication fork processing [GO:1990426]; multicellular organism growth [GO:0035264]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; nucleotide-excision repair [GO:0006289]; oocyte maturation [GO:0001556]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mitotic cell cycle [GO:0045931]; regulation of cytokinesis [GO:0032465]; regulation of DNA-templated transcription [GO:0006355]; replication fork protection [GO:0048478]; response to estradiol [GO:0032355]; response to gamma radiation [GO:0010332]; response to nutrient [GO:0007584]; response to UV-C [GO:0010225]; response to X-ray [GO:0010165]; spermatogenesis [GO:0007283]; stem cell proliferation [GO:0072089]; telomere maintenance via recombination [GO:0000722] GO:0000152; GO:0000722; GO:0000724; GO:0000781; GO:0000800; GO:0001556; GO:0001833; GO:0002020; GO:0003697; GO:0005634; GO:0005694; GO:0005737; GO:0005813; GO:0006289; GO:0006302; GO:0006310; GO:0006355; GO:0006974; GO:0006978; GO:0007141; GO:0007283; GO:0007420; GO:0007584; GO:0008022; GO:0008283; GO:0008585; GO:0008630; GO:0010165; GO:0010225; GO:0010332; GO:0010484; GO:0010485; GO:0030097; GO:0030141; GO:0030879; GO:0031619; GO:0032355; GO:0032465; GO:0032991; GO:0033593; GO:0033600; GO:0035264; GO:0042771; GO:0042802; GO:0043009; GO:0043015; GO:0043966; GO:0043967; GO:0045893; GO:0045931; GO:0048478; GO:0051276; GO:0051298; GO:0070200; GO:0071425; GO:0071479; GO:0072089; GO:0090398; GO:1990391; GO:1990426 14698 XM_029337318.2 125 155 0 223 151 Q1LZI2 3.61e-67 Putative thiamine transporter SLC35F3 (Solute carrier family 35 member F3) Mus musculus (Mouse) thiamine transport [GO:0015888] GO:0015888; GO:0016020 14699 XM_044318282.1 2 0 4 7 34 NA NA NA NA NA NA 14700 XM_044322306.1 50 18 21 37 20 Q07496 1.21e-22 Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) (cEK8) Gallus gallus (Chicken) axon guidance [GO:0007411]; cell adhesion [GO:0007155]; fasciculation of sensory neuron axon [GO:0097155]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of kinase activity [GO:0033674]; positive regulation of Rho guanyl-nucleotide exchange factor activity [GO:2001108]; protein autophosphorylation [GO:0046777]; regulation of GTPase activity [GO:0043087]; segmentation [GO:0035282]; somitogenesis [GO:0001756]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0001756; GO:0004672; GO:0004714; GO:0005004; GO:0005005; GO:0005524; GO:0005737; GO:0005886; GO:0007155; GO:0007169; GO:0007411; GO:0018108; GO:0031901; GO:0033674; GO:0035282; GO:0043005; GO:0043087; GO:0043197; GO:0043235; GO:0046777; GO:0097155; GO:0097161; GO:2001108 14701 XM_029325995.2 213 0 59 2 120 NA NA NA NA NA NA 14702 XM_044324877.1 9 9 5 17 0 NA NA NA NA NA NA 14703 XM_044323559.1 1483 1355 671 1189 1783 NA NA NA NA NA NA 14704 XR_006391626.1 423 250 165 1665 898 NA NA NA NA NA NA 14705 XM_029347274.2 162 118 131 225 243 Q9TXH9 1.22e-36 UBX domain-containing protein 1 Caenorhabditis elegans cell differentiation [GO:0030154]; masculinization of hermaphroditic germ-line [GO:0042006]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein K48-linked deubiquitination [GO:1903094]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of protein catabolic process [GO:0045732]; spermatogenesis [GO:0007283] GO:0005634; GO:0005737; GO:0007283; GO:0030154; GO:0031397; GO:0032435; GO:0036435; GO:0042006; GO:0045732; GO:0048471; GO:1903094 14706 XM_029331263.2 0 21 13 0 99 NA NA NA NA NA NA 14707 XM_044309787.1 0 0 18 0 9 NA NA NA NA NA NA 14708 XM_029336583.2 1176 1260 792 1424 972 Q8R1X6 7.38e-53 Spartin Mus musculus (Mouse) abscission [GO:0009838]; adipose tissue development [GO:0060612]; BMP signaling pathway [GO:0030509]; cell division [GO:0051301]; collateral sprouting in absence of injury [GO:0048669]; lipid droplet organization [GO:0034389]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of collateral sprouting in absence of injury [GO:0048698]; neuromuscular process [GO:0050905]; regulation of mitochondrial membrane potential [GO:0051881] GO:0005737; GO:0005741; GO:0005811; GO:0005829; GO:0005886; GO:0009838; GO:0030496; GO:0030509; GO:0030514; GO:0031625; GO:0034389; GO:0045202; GO:0048669; GO:0048698; GO:0050905; GO:0051301; GO:0051881; GO:0060612 14709 XM_029331412.2 1183 1181 729 1004 1104 Q8BWD8 0 Cyclin-dependent kinase 19 (EC 2.7.11.22) (CDC2-related protein kinase 6) (Cell division cycle 2-like protein kinase 6) (Cell division protein kinase 19) Mus musculus (Mouse) cellular response to lipopolysaccharide [GO:0071222]; positive regulation of apoptotic process [GO:0043065]; positive regulation of inflammatory response [GO:0050729]; protein phosphorylation [GO:0006468] GO:0004693; GO:0005524; GO:0005634; GO:0005654; GO:0005829; GO:0006468; GO:0016592; GO:0043065; GO:0048471; GO:0050729; GO:0071222; GO:0106310 14710 XM_029343818.2 73 51 191 26 262 Q8BZL4 1.45e-24 G-protein coupled receptor 22 Mus musculus (Mouse) cell projection organization [GO:0030030]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0005886; GO:0007186; GO:0030030; GO:0042277 14711 XM_029355419.2 1339 2198 733 844 716 Q3MHX1 1.09e-64 COMM domain-containing protein 7 Bos taurus (Bovine) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0031410; GO:0032088; GO:0033209; GO:0045892; GO:0051059 14712 XM_029341442.2 347 305 93 329 614 Q6NUT3 4.38e-79 Major facilitator superfamily domain-containing protein 12 Homo sapiens (Human) carbohydrate transport [GO:0008643]; cysteine transmembrane transport [GO:1903712]; melanin biosynthetic process [GO:0042438]; negative regulation of melanin biosynthetic process [GO:0048022]; organic substance transport [GO:0071702]; pigment metabolic process involved in pigmentation [GO:0043474]; regulation of melanin biosynthetic process [GO:0048021] GO:0005764; GO:0005765; GO:0005770; GO:0005886; GO:0008643; GO:0015293; GO:0033162; GO:0033229; GO:0042438; GO:0042470; GO:0043474; GO:0048021; GO:0048022; GO:0071702; GO:1903712 14713 XM_029345030.2 470 365 317 510 953 NA NA NA NA NA NA 14714 XM_029335986.2 584 460 522 659 644 P85037 3.05e-125 Forkhead box protein K1 (Myocyte nuclear factor) (MNF) Homo sapiens (Human) canonical glycolysis [GO:0061621]; cell differentiation [GO:0030154]; cellular glucose homeostasis [GO:0001678]; muscle organ development [GO:0007517]; negative regulation of autophagy [GO:0010507]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of glucose metabolic process [GO:0010906]; regulation of transcription by RNA polymerase II [GO:0006357]; response to starvation [GO:0042594] GO:0000785; GO:0000976; GO:0000978; GO:0000981; GO:0001227; GO:0001678; GO:0003700; GO:0005634; GO:0005654; GO:0005737; GO:0006357; GO:0007517; GO:0010507; GO:0010906; GO:0030154; GO:0042594; GO:0045892; GO:0045893; GO:0061621; GO:0071889; GO:1990837 14715 XM_044317118.1 0 10 0 19 51 NA NA NA NA NA NA 14716 XR_006395636.1 0 0 11 0 8 NA NA NA NA NA NA 14717 XM_044328554.1 19 15 25 16 0 Q8K2J9 1.96e-74 BTB/POZ domain-containing protein 6 Mus musculus (Mouse) neurogenesis [GO:0022008] GO:0005829; GO:0022008 14718 XM_044308977.1 361 132 198 183 489 NA NA NA NA NA NA 14719 XM_044322329.1 0 1 7 9 4 NA NA NA NA NA NA 14720 XM_044322070.1 1 0 5 0 18 NA NA NA NA NA NA 14721 XM_044318808.1 0 0 0 23 133 B3EWY9 0 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 14722 XM_044318808.1 0 0 0 23 133 B3EWY9 0 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 14723 XM_044318808.1 0 0 0 23 133 B3EWY9 2.16e-34 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 14724 XM_044318808.1 0 0 0 23 133 B3EWY9 5.19e-33 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 14725 XM_044315428.1 29 47 11 68 25 NA NA NA NA NA NA 14726 XR_006395684.1 25 2 6 9 6 NA NA NA NA NA NA 14727 XM_029356230.2 794 925 656 330 1098 Q91W97 2.71e-111 Hexokinase HKDC1 (EC 2.7.1.1) (Hexokinase domain-containing protein 1) Mus musculus (Mouse) carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; glucose 6-phosphate metabolic process [GO:0051156]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096] GO:0001678; GO:0001917; GO:0004340; GO:0005524; GO:0005536; GO:0005737; GO:0005739; GO:0005829; GO:0006006; GO:0006096; GO:0008865; GO:0031966; GO:0046835; GO:0051156 14728 XM_029356230.2 794 925 656 330 1098 Q91W97 8.22e-102 Hexokinase HKDC1 (EC 2.7.1.1) (Hexokinase domain-containing protein 1) Mus musculus (Mouse) carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; glucose 6-phosphate metabolic process [GO:0051156]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096] GO:0001678; GO:0001917; GO:0004340; GO:0005524; GO:0005536; GO:0005737; GO:0005739; GO:0005829; GO:0006006; GO:0006096; GO:0008865; GO:0031966; GO:0046835; GO:0051156 14729 XM_029349610.2 41 0 0 9 0 NA NA NA NA NA NA 14730 XM_044329280.1 50 32 52 32 158 NA NA NA NA NA NA 14731 XM_044312923.1 942 1509 440 1193 5 O09167 7.33e-34 60S ribosomal protein L21 Mus musculus (Mouse) cytoplasmic translation [GO:0002181] GO:0002181; GO:0003735; GO:0005737; GO:0005783; GO:0005829; GO:0005840; GO:0022625; GO:0022626; GO:0045202; GO:0098794 14732 XR_003826164.2 0 0 0 14 11 NA NA NA NA NA NA 14733 XM_029342191.2 888 1070 354 27 608 Q5VTB9 5.43e-58 E3 ubiquitin-protein ligase RNF220 (EC 2.3.2.27) (RING finger protein 220) (RING-type E3 ubiquitin transferase RNF220) Homo sapiens (Human) dorsal/ventral neural tube patterning [GO:0021904]; noradrenergic neuron development [GO:0003358]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; protein autoubiquitination [GO:0051865]; protein monoubiquitination [GO:0006513]; protein ubiquitination [GO:0016567]; regulation of transcription regulatory region DNA binding [GO:2000677] GO:0003358; GO:0004842; GO:0005634; GO:0005652; GO:0005737; GO:0006513; GO:0008013; GO:0016567; GO:0021904; GO:0032991; GO:0046872; GO:0051091; GO:0051865; GO:0061630; GO:0090263; GO:2000677 14734 XM_029323966.2 13 20 0 17 17 NA NA NA NA NA NA 14735 XM_044308736.1 566 41 52 351 190 NA NA NA NA NA NA 14736 XM_029330237.2 0 187 420 530 618 Q03164 3.82e-123 Histone-lysine N-methyltransferase 2A (Lysine N-methyltransferase 2A) (EC 2.1.1.364) (ALL-1) (CXXC-type zinc finger protein 7) (Cysteine methyltransferase KMT2A) (EC 2.1.1.-) (Myeloid/lymphoid or mixed-lineage leukemia) (Myeloid/lymphoid or mixed-lineage leukemia protein 1) (Trithorax-like protein) (Zinc finger protein HRX) [Cleaved into: MLL cleavage product N320 (N-terminal cleavage product of 320 kDa) (p320); MLL cleavage product C180 (C-terminal cleavage product of 180 kDa) (p180)] Homo sapiens (Human) anterior/posterior pattern specification [GO:0009952]; apoptotic process [GO:0006915]; circadian regulation of gene expression [GO:0032922]; definitive hemopoiesis [GO:0060216]; DNA methylation [GO:0006306]; embryonic hemopoiesis [GO:0035162]; exploration behavior [GO:0035640]; fibroblast proliferation [GO:0048144]; histone H3-K4 dimethylation [GO:0044648]; histone H3-K4 methylation [GO:0051568]; histone H3-K4 monomethylation [GO:0097692]; histone H3-K4 trimethylation [GO:0080182]; histone modification [GO:0016570]; homeostasis of number of cells within a tissue [GO:0048873]; membrane depolarization [GO:0051899]; negative regulation of DNA methylation [GO:1905642]; negative regulation of fibroblast proliferation [GO:0048147]; peptidyl-lysine monomethylation [GO:0018026]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transporter activity [GO:0032411]; post-embryonic development [GO:0009791]; protein-containing complex assembly [GO:0065003]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; response to potassium ion [GO:0035864]; spleen development [GO:0048536]; T-helper 2 cell differentiation [GO:0045064]; transcription initiation-coupled chromatin remodeling [GO:0045815]; visual learning [GO:0008542] GO:0003680; GO:0003682; GO:0005634; GO:0005654; GO:0005829; GO:0006306; GO:0006915; GO:0008270; GO:0008542; GO:0009791; GO:0009952; GO:0016570; GO:0018026; GO:0032411; GO:0032922; GO:0035097; GO:0035162; GO:0035640; GO:0035864; GO:0042800; GO:0042802; GO:0042803; GO:0044648; GO:0045064; GO:0045322; GO:0045815; GO:0045893; GO:0045944; GO:0048144; GO:0048147; GO:0048172; GO:0048536; GO:0048873; GO:0051568; GO:0051899; GO:0060216; GO:0065003; GO:0070577; GO:0071339; GO:0080182; GO:0097692; GO:0106363; GO:0140945; GO:1905642 14737 XM_029330237.2 0 187 420 530 618 Q03164 1.64e-100 Histone-lysine N-methyltransferase 2A (Lysine N-methyltransferase 2A) (EC 2.1.1.364) (ALL-1) (CXXC-type zinc finger protein 7) (Cysteine methyltransferase KMT2A) (EC 2.1.1.-) (Myeloid/lymphoid or mixed-lineage leukemia) (Myeloid/lymphoid or mixed-lineage leukemia protein 1) (Trithorax-like protein) (Zinc finger protein HRX) [Cleaved into: MLL cleavage product N320 (N-terminal cleavage product of 320 kDa) (p320); MLL cleavage product C180 (C-terminal cleavage product of 180 kDa) (p180)] Homo sapiens (Human) anterior/posterior pattern specification [GO:0009952]; apoptotic process [GO:0006915]; circadian regulation of gene expression [GO:0032922]; definitive hemopoiesis [GO:0060216]; DNA methylation [GO:0006306]; embryonic hemopoiesis [GO:0035162]; exploration behavior [GO:0035640]; fibroblast proliferation [GO:0048144]; histone H3-K4 dimethylation [GO:0044648]; histone H3-K4 methylation [GO:0051568]; histone H3-K4 monomethylation [GO:0097692]; histone H3-K4 trimethylation [GO:0080182]; histone modification [GO:0016570]; homeostasis of number of cells within a tissue [GO:0048873]; membrane depolarization [GO:0051899]; negative regulation of DNA methylation [GO:1905642]; negative regulation of fibroblast proliferation [GO:0048147]; peptidyl-lysine monomethylation [GO:0018026]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transporter activity [GO:0032411]; post-embryonic development [GO:0009791]; protein-containing complex assembly [GO:0065003]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; response to potassium ion [GO:0035864]; spleen development [GO:0048536]; T-helper 2 cell differentiation [GO:0045064]; transcription initiation-coupled chromatin remodeling [GO:0045815]; visual learning [GO:0008542] GO:0003680; GO:0003682; GO:0005634; GO:0005654; GO:0005829; GO:0006306; GO:0006915; GO:0008270; GO:0008542; GO:0009791; GO:0009952; GO:0016570; GO:0018026; GO:0032411; GO:0032922; GO:0035097; GO:0035162; GO:0035640; GO:0035864; GO:0042800; GO:0042802; GO:0042803; GO:0044648; GO:0045064; GO:0045322; GO:0045815; GO:0045893; GO:0045944; GO:0048144; GO:0048147; GO:0048172; GO:0048536; GO:0048873; GO:0051568; GO:0051899; GO:0060216; GO:0065003; GO:0070577; GO:0071339; GO:0080182; GO:0097692; GO:0106363; GO:0140945; GO:1905642 14738 XR_006391289.1 43 6 10 2 7 NA NA NA NA NA NA 14739 XM_044319741.1 21 64 8 139 0 NA NA NA NA NA NA 14740 XM_044309596.1 542 276 282 529 594 Q9P2K1 0 Coiled-coil and C2 domain-containing protein 2A Homo sapiens (Human) axoneme assembly [GO:0035082]; camera-type eye development [GO:0043010]; cilium assembly [GO:0060271]; determination of left/right symmetry [GO:0007368]; embryonic brain development [GO:1990403]; heart development [GO:0007507]; kidney development [GO:0001822]; motile cilium assembly [GO:0044458]; neural tube closure [GO:0001843]; non-motile cilium assembly [GO:1905515]; protein localization to ciliary transition zone [GO:1904491]; smoothened signaling pathway [GO:0007224] GO:0001822; GO:0001843; GO:0005829; GO:0005856; GO:0007224; GO:0007368; GO:0007507; GO:0035082; GO:0035869; GO:0036038; GO:0043010; GO:0044458; GO:0060271; GO:1904491; GO:1905515; GO:1990403 14741 XM_044314719.1 3212 3244 2644 39 2350 NA NA NA NA NA NA 14742 XM_029323642.2 172 293 729 88 451 Q5BJT4 3.12e-34 Thioredoxin domain-containing protein 15 Rattus norvegicus (Rat) cilium assembly [GO:0060271]; positive regulation of smoothened signaling pathway [GO:0045880] GO:0005929; GO:0045880; GO:0060170; GO:0060271 14743 XM_029342980.2 538 309 204 219 276 Q9DAC7 4.2e-21 Tetratricopeptide repeat protein 32 (TPR repeat protein 32) Mus musculus (Mouse) NA NA 14744 XM_029340657.2 58 18 21 18 45 NA NA NA NA NA NA 14745 XM_044328537.1 84 114 102 88 121 Q64077 9.47e-22 Substance-K receptor (SKR) (NK-2 receptor) (NK-2R) (Neurokinin A receptor) (Tachykinin receptor 2) Cavia porcellus (Guinea pig) positive regulation of flagellated sperm motility [GO:1902093]; regulation of uterine smooth muscle contraction [GO:0070472] GO:0004995; GO:0005886; GO:0061827; GO:0070472; GO:0097225; GO:1902093 14746 XM_044320146.1 21 9 0 0 5 NA NA NA NA NA NA 14747 XM_044320700.1 0 0 4 0 13 Q14766 5.5e-55 Latent-transforming growth factor beta-binding protein 1 (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1) Homo sapiens (Human) regulation of transforming growth factor beta activation [GO:1901388]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0005024; GO:0005509; GO:0005576; GO:0005788; GO:0031012; GO:0032991; GO:0035583; GO:0050431; GO:0050436; GO:0062023; GO:1901388 14748 XM_044320700.1 0 0 4 0 13 Q14766 3.6e-50 Latent-transforming growth factor beta-binding protein 1 (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1) Homo sapiens (Human) regulation of transforming growth factor beta activation [GO:1901388]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0005024; GO:0005509; GO:0005576; GO:0005788; GO:0031012; GO:0032991; GO:0035583; GO:0050431; GO:0050436; GO:0062023; GO:1901388 14749 XM_044320700.1 0 0 4 0 13 Q14766 3.71e-50 Latent-transforming growth factor beta-binding protein 1 (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1) Homo sapiens (Human) regulation of transforming growth factor beta activation [GO:1901388]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0005024; GO:0005509; GO:0005576; GO:0005788; GO:0031012; GO:0032991; GO:0035583; GO:0050431; GO:0050436; GO:0062023; GO:1901388 14750 XM_044320700.1 0 0 4 0 13 Q14766 9.57e-42 Latent-transforming growth factor beta-binding protein 1 (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1) Homo sapiens (Human) regulation of transforming growth factor beta activation [GO:1901388]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0005024; GO:0005509; GO:0005576; GO:0005788; GO:0031012; GO:0032991; GO:0035583; GO:0050431; GO:0050436; GO:0062023; GO:1901388 14751 XM_044326800.1 31 4 8 41 44 NA NA NA NA NA NA 14752 XM_029329690.2 1209 648 507 941 781 Q9UNH7 8.27e-33 Sorting nexin-6 (TRAF4-associated factor 2) [Cleaved into: Sorting nexin-6, N-terminally processed] Homo sapiens (Human) cellular response to amyloid-beta [GO:1904646]; intracellular protein transport [GO:0006886]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; regulation of macroautophagy [GO:0016241]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; retrograde transport, endosome to Golgi [GO:0042147] GO:0005634; GO:0005737; GO:0005764; GO:0005768; GO:0005829; GO:0006886; GO:0007175; GO:0016241; GO:0030512; GO:0030904; GO:0030905; GO:0031901; GO:0034452; GO:0034713; GO:0035091; GO:0042147; GO:0042803; GO:0043524; GO:0045892; GO:0097422; GO:0098978; GO:0099072; GO:1904646 14753 XR_006397504.1 140 597 118 497 180 NA NA NA NA NA NA 14754 XM_044326917.1 39 7 0 29 53 NA NA NA NA NA NA 14755 XM_029334459.2 10 59 27 53 46 Q26636 4.44e-121 Cathepsin L (EC 3.4.22.15) [Cleaved into: Cathepsin L heavy chain; Cathepsin L light chain] Sarcophaga peregrina (Flesh fly) (Boettcherisca peregrina) cell differentiation [GO:0030154]; proteolysis [GO:0006508] GO:0004197; GO:0005764; GO:0006508; GO:0030154 14756 XM_044324523.1 2472 1859 1230 1965 2041 A7MBP4 3.4e-124 Intraflagellar transport protein 46 homolog Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; determination of ventral identity [GO:0048264]; intraciliary transport [GO:0042073]; pronephros development [GO:0048793]; retina development in camera-type eye [GO:0060041] GO:0005737; GO:0005813; GO:0030992; GO:0031514; GO:0036064; GO:0042073; GO:0048264; GO:0048793; GO:0060041; GO:0060271 14757 XM_044317657.1 220 156 144 11 195 Q9Y4P3 2.18e-122 Transducin beta-like protein 2 (WS beta-transducin repeats protein) (WS-betaTRP) (Williams-Beuren syndrome chromosomal region 13 protein) Homo sapiens (Human) cellular response to glucose starvation [GO:0042149]; cellular response to hypoxia [GO:0071456]; endoplasmic reticulum unfolded protein response [GO:0030968] GO:0003723; GO:0005783; GO:0005789; GO:0019901; GO:0030968; GO:0031369; GO:0042149; GO:0051219; GO:0071456 14758 XM_029337126.2 122 371 111 186 184 NA NA NA NA NA NA 14759 XM_044327826.1 0 0 8 15 12 NA NA NA NA NA NA 14760 XM_044318580.1 13 3 15 21 109 Q68F72 6.51e-31 Solute carrier family 15 member 4 Xenopus laevis (African clawed frog) dipeptide import across plasma membrane [GO:0140206]; innate immune response [GO:0045087]; mast cell homeostasis [GO:0033023]; peptidoglycan transport [GO:0015835]; positive regulation of innate immune response [GO:0045089]; positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [GO:0070430]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of toll-like receptor 7 signaling pathway [GO:0034157]; positive regulation of toll-like receptor 8 signaling pathway [GO:0034161]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; protein transport [GO:0015031]; regulation of isotype switching to IgG isotypes [GO:0048302]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424] GO:0005290; GO:0005765; GO:0015031; GO:0015333; GO:0015647; GO:0015835; GO:0031901; GO:0033023; GO:0034157; GO:0034161; GO:0034165; GO:0036020; GO:0045087; GO:0045089; GO:0048302; GO:0070424; GO:0070430; GO:0070434; GO:0071916; GO:0140206 14761 XM_044318266.1 375 217 168 75 90 P31422 0 Metabotropic glutamate receptor 3 (mGluR3) Rattus norvegicus (Rat) G protein-coupled glutamate receptor signaling pathway [GO:0007216]; gene expression [GO:0010467]; modulation of chemical synaptic transmission [GO:0050804]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; regulation of synaptic transmission, glutamatergic [GO:0051966]; sensory perception of pain [GO:0019233] GO:0001640; GO:0001641; GO:0005246; GO:0005886; GO:0007216; GO:0010467; GO:0014069; GO:0019233; GO:0030424; GO:0042734; GO:0043005; GO:0043197; GO:0045211; GO:0050804; GO:0051966; GO:0097110; GO:0097449; GO:0098794; GO:0098978; GO:0099170 14762 XM_044319825.1 0 26 4 0 27 A8DZE6 7.21e-58 Wilms tumor protein 1-interacting protein homolog (WT1-interacting protein homolog) Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; cloaca development [GO:0035844]; cytoskeleton organization [GO:0007010]; determination of heart left/right asymmetry [GO:0061371]; determination of left/right asymmetry in lateral mesoderm [GO:0003140]; establishment of mitotic spindle orientation [GO:0000132]; heart looping [GO:0001947]; negative regulation of hippo signaling [GO:0035331]; neural crest cell development [GO:0014032]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; regulation of cell morphogenesis [GO:0022604]; regulation of DNA-templated transcription [GO:0006355]; response to hypoxia [GO:0001666]; visceral serous pericardium development [GO:0061032] GO:0000132; GO:0000932; GO:0001666; GO:0001947; GO:0003140; GO:0003714; GO:0005634; GO:0005667; GO:0005912; GO:0006355; GO:0007010; GO:0014032; GO:0022604; GO:0035331; GO:0035844; GO:0036064; GO:0046872; GO:0060271; GO:0061032; GO:0061371; GO:2000637 14763 XM_029340366.2 37 19 41 12 102 Q9Z0H0 1.59e-45 Cell division cycle 7-related protein kinase (CDC7-related kinase) (muCdc7) (EC 2.7.11.1) Mus musculus (Mouse) cell cycle phase transition [GO:0044770]; cell division [GO:0051301]; double-strand break repair via break-induced replication [GO:0000727]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of nuclear cell cycle DNA replication [GO:0010571]; signal transduction [GO:0007165] GO:0000727; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0007165; GO:0008284; GO:0010571; GO:0010971; GO:0016301; GO:0018105; GO:0044770; GO:0045171; GO:0046872; GO:0051301; GO:0072686; GO:0106310 14764 XM_029340366.2 37 19 41 12 102 Q9Z0H0 6.41e-35 Cell division cycle 7-related protein kinase (CDC7-related kinase) (muCdc7) (EC 2.7.11.1) Mus musculus (Mouse) cell cycle phase transition [GO:0044770]; cell division [GO:0051301]; double-strand break repair via break-induced replication [GO:0000727]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of nuclear cell cycle DNA replication [GO:0010571]; signal transduction [GO:0007165] GO:0000727; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0007165; GO:0008284; GO:0010571; GO:0010971; GO:0016301; GO:0018105; GO:0044770; GO:0045171; GO:0046872; GO:0051301; GO:0072686; GO:0106310 14765 XM_044320830.1 61 49 25 19 9 NA NA NA NA NA NA 14766 XM_044325886.1 65 158 74 95 160 Q16820 9.06e-35 Meprin A subunit beta (EC 3.4.24.63) (Endopeptidase-2) (Meprin B) (N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta) (PABA peptide hydrolase) (PPH beta) Homo sapiens (Human) inflammatory response [GO:0006954]; proteolysis [GO:0006508]; toxin transport [GO:1901998] GO:0004222; GO:0005576; GO:0005886; GO:0006508; GO:0006954; GO:0008270; GO:0017090; GO:0042802; GO:1901998 14767 XR_006391696.1 0 0 0 8 12 NA NA NA NA NA NA 14768 XM_044328280.1 0 4 0 8 0 NA NA NA NA NA NA 14769 XM_044314391.1 129 36 43 48 15 NA NA NA NA NA NA 14770 XM_044325052.1 95 129 52 110 46 NA NA NA NA NA NA 14771 XM_029335050.2 1930 1548 1072 1214 894 NA NA NA NA NA NA 14772 XM_044316398.1 53 34 33 8 46 Q9M2U3 1.28e-24 Protein ALP1-like (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) NA GO:0000118; GO:0004518; GO:0046872 14773 XM_029349831.2 2150 5050 1869 3561 1032 NA NA NA NA NA NA 14774 XM_029332952.2 0 248 73 280 188 NA NA NA NA NA NA 14775 XM_029324317.2 335 159 84 147 189 Q08BB2 1.36e-136 N-fatty-acyl-amino acid synthase/hydrolase PM20D1.2 (EC 3.5.1.114) (EC 3.5.1.14) (Peptidase M20 domain-containing protein 1.2) Danio rerio (Zebrafish) (Brachydanio rerio) adaptive thermogenesis [GO:1990845]; amide biosynthetic process [GO:0043604]; amide catabolic process [GO:0043605]; amino acid metabolic process [GO:0006520]; cellular lipid metabolic process [GO:0044255]; energy homeostasis [GO:0097009]; fatty acid metabolic process [GO:0006631]; nitrogen compound metabolic process [GO:0006807]; proteolysis [GO:0006508]; regulation of oxidative phosphorylation uncoupler activity [GO:2000275]; respiratory electron transport chain [GO:0022904] GO:0004046; GO:0004181; GO:0005615; GO:0006508; GO:0006520; GO:0006631; GO:0006807; GO:0016811; GO:0016829; GO:0022904; GO:0043604; GO:0043605; GO:0044255; GO:0046872; GO:0097009; GO:1990845; GO:2000275 14776 XM_044311669.1 13 20 17 23 19 Q7RTR2 3.34e-39 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 14777 XM_029355422.2 0 3 7 1 0 NA NA NA NA NA NA 14778 XM_029348294.2 33 44 20 89 114 Q0IHA2 1.61e-54 Elongator complex protein 6 (Protein TMEM103) Xenopus laevis (African clawed frog) positive regulation of cell migration [GO:0030335]; tRNA wobble uridine modification [GO:0002098] GO:0002098; GO:0030335; GO:0033588 14779 XR_003825863.2 275 769 390 321 93 NA NA NA NA NA NA 14780 XM_029338325.2 429 204 241 587 687 Q6TFL3 0 Coiled-coil domain-containing protein 171 Homo sapiens (Human) NA NA 14781 XM_044324164.1 27 5 3 21 73 Q8TE60 1.98e-88 A disintegrin and metalloproteinase with thrombospondin motifs 18 (ADAM-TS 18) (ADAM-TS18) (ADAMTS-18) (EC 3.4.24.-) Homo sapiens (Human) extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; negative regulation of platelet aggregation [GO:0090331]; proteolysis [GO:0006508] GO:0001654; GO:0004222; GO:0005576; GO:0006508; GO:0030198; GO:0031012; GO:0046872; GO:0090331 14782 XM_044324164.1 27 5 3 21 73 Q8TE60 1.89e-21 A disintegrin and metalloproteinase with thrombospondin motifs 18 (ADAM-TS 18) (ADAM-TS18) (ADAMTS-18) (EC 3.4.24.-) Homo sapiens (Human) extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; negative regulation of platelet aggregation [GO:0090331]; proteolysis [GO:0006508] GO:0001654; GO:0004222; GO:0005576; GO:0006508; GO:0030198; GO:0031012; GO:0046872; GO:0090331 14783 XM_044321288.1 1049 1 0 935 231 Q7RTR2 5.61e-39 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 14784 XM_044321288.1 1049 1 0 935 231 Q7RTR2 8.61e-36 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 14785 XM_044321288.1 1049 1 0 935 231 Q7RTR2 5.21e-32 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 14786 XM_044321288.1 1049 1 0 935 231 Q7RTR2 3.33e-30 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 14787 XM_044321288.1 1049 1 0 935 231 Q7RTR2 4.74e-29 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 14788 XM_029353237.2 1751 1416 1184 1474 1143 Q4QRK0 0 Methionine aminopeptidase 1 (MAP 1) (MetAP 1) (EC 3.4.11.18) (Peptidase M 1) Danio rerio (Zebrafish) (Brachydanio rerio) protein initiator methionine removal involved in protein maturation [GO:0035551] GO:0005829; GO:0035551; GO:0046872; GO:0070006 14789 XR_006394270.1 11 4 43 9 189 NA NA NA NA NA NA 14790 XM_044308014.1 0 0 94 47 1 NA NA NA NA NA NA 14791 XM_029352216.2 36 80 48 39 41 NA NA NA NA NA NA 14792 XR_006396799.1 0 0 0 1 13 NA NA NA NA NA NA 14793 XM_029357327.2 397 833 397 574 518 Q6VAB6 1.68e-85 Kinase suppressor of Ras 2 (hKSR2) (EC 2.7.11.1) Homo sapiens (Human) calcium-mediated signaling [GO:0019722]; positive regulation of cold-induced thermogenesis [GO:0120162]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; signal transduction [GO:0007165] GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006468; GO:0007165; GO:0007265; GO:0019722; GO:0046872; GO:0106310; GO:0120162 14794 XM_029357327.2 397 833 397 574 518 Q6VAB6 3.06e-22 Kinase suppressor of Ras 2 (hKSR2) (EC 2.7.11.1) Homo sapiens (Human) calcium-mediated signaling [GO:0019722]; positive regulation of cold-induced thermogenesis [GO:0120162]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; signal transduction [GO:0007165] GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006468; GO:0007165; GO:0007265; GO:0019722; GO:0046872; GO:0106310; GO:0120162 14795 XM_044325630.1 15 0 6 0 10 NA NA NA NA NA NA 14796 XM_044322865.1 0 207 124 167 0 NA NA NA NA NA NA 14797 XM_029328574.2 0 125 45 0 0 NA NA NA NA NA NA 14798 XR_006395479.1 443 276 238 441 423 NA NA NA NA NA NA 14799 XM_044318599.1 44 4 8 47 21 A0JM23 1.71e-50 Nephrocystin-3 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cilium assembly [GO:0060271]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; Wnt signaling pathway [GO:0016055] GO:0005929; GO:0016055; GO:0060271; GO:0090090; GO:2000095 14800 XM_044318599.1 44 4 8 47 21 A0JM23 1.85e-47 Nephrocystin-3 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cilium assembly [GO:0060271]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; Wnt signaling pathway [GO:0016055] GO:0005929; GO:0016055; GO:0060271; GO:0090090; GO:2000095 14801 XM_044318599.1 44 4 8 47 21 A0JM23 1.83e-44 Nephrocystin-3 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cilium assembly [GO:0060271]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; Wnt signaling pathway [GO:0016055] GO:0005929; GO:0016055; GO:0060271; GO:0090090; GO:2000095 14802 XM_044318599.1 44 4 8 47 21 A0JM23 2.62e-43 Nephrocystin-3 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cilium assembly [GO:0060271]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; Wnt signaling pathway [GO:0016055] GO:0005929; GO:0016055; GO:0060271; GO:0090090; GO:2000095 14803 XM_044318599.1 44 4 8 47 21 A0JM23 6.58e-37 Nephrocystin-3 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cilium assembly [GO:0060271]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; Wnt signaling pathway [GO:0016055] GO:0005929; GO:0016055; GO:0060271; GO:0090090; GO:2000095 14804 XM_044321232.1 130 135 50 75 131 NA NA NA NA NA NA 14805 XM_044320375.1 0 10 0 1 9 NA NA NA NA NA NA 14806 XM_044327544.1 654 49 21 161 78 NA NA NA NA NA NA 14807 XM_029330661.2 226 105 118 158 334 NA NA NA NA NA NA 14808 XM_029346597.2 75 89 54 72 147 NA NA NA NA NA NA 14809 XM_044325757.1 106 58 0 114 276 NA NA NA NA NA NA 14810 XM_029340308.2 613 545 437 464 723 NA NA NA NA NA NA 14811 XM_044325976.1 135 227 0 0 27 NA NA NA NA NA NA 14812 XM_044327851.1 214 54 84 218 111 NA NA NA NA NA NA 14813 XR_006391853.1 0 25 0 0 0 NA NA NA NA NA NA 14814 XM_044323515.1 213 50 262 257 433 NA NA NA NA NA NA 14815 XM_029329135.2 5155 3395 3300 3824 2268 NA NA NA NA NA NA 14816 XM_029337523.2 1609 1341 984 1168 969 Q9NZS9 2.37e-68 Bifunctional apoptosis regulator (RING finger protein 47) Homo sapiens (Human) apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000209; GO:0005783; GO:0005789; GO:0005886; GO:0006511; GO:0006915; GO:0016020; GO:0030674; GO:0043066; GO:0043161; GO:0046872; GO:0051865; GO:0061630; GO:0070534; GO:0070936; GO:0089720; GO:1903895 14817 XM_029346273.2 1223 961 658 1063 1175 Q6P632 8.47e-96 N-alpha-acetyltransferase 20 (EC 2.3.1.254) (Methionine N-acetyltransferase) (N-acetyltransferase 5) (N-terminal acetyltransferase B complex catalytic subunit NAA20) (N-terminal acetyltransferase B complex catalytic subunit NAT5) (NatB complex subunit NAT5) (NatB catalytic subunit) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) N-terminal peptidyl-aspartic acid acetylation [GO:0017190]; N-terminal peptidyl-glutamic acid acetylation [GO:0018002]; N-terminal peptidyl-glutamine acetylation [GO:0017192]; N-terminal protein amino acid acetylation [GO:0006474] GO:0005634; GO:0005737; GO:0006474; GO:0016747; GO:0017190; GO:0017192; GO:0018002 14818 XM_029339558.2 226 235 130 146 163 NA NA NA NA NA NA 14819 XM_029335579.2 0 0 29 9 19 NA NA NA NA NA NA 14820 XM_029334545.2 3093 4280 3496 4247 4362 P61244 4.28e-46 Protein max (Class D basic helix-loop-helix protein 4) (bHLHd4) (Myc-associated factor X) Homo sapiens (Human) cellular response to peptide hormone stimulus [GO:0071375]; cellular response to starvation [GO:0009267]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron apoptotic process [GO:0051402]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein-containing complex assembly [GO:0065003]; regulation of transcription by RNA polymerase II [GO:0006357]; response to axon injury [GO:0048678]; response to insulin [GO:0032868]; retina development in camera-type eye [GO:0060041] GO:0000122; GO:0000785; GO:0000981; GO:0001227; GO:0003676; GO:0003677; GO:0003700; GO:0005634; GO:0005654; GO:0005737; GO:0006357; GO:0009267; GO:0010629; GO:0016605; GO:0030425; GO:0032868; GO:0032993; GO:0042802; GO:0044877; GO:0045893; GO:0045944; GO:0046983; GO:0048678; GO:0051402; GO:0060041; GO:0065003; GO:0070443; GO:0070888; GO:0071339; GO:0071375; GO:0071943; GO:0090575; GO:0140297; GO:1990837 14821 XM_044321533.1 149 62 62 53 110 NA NA NA NA NA NA 14822 XM_029328791.2 1909 1354 673 1131 876 NA NA NA NA NA NA 14823 XR_006398126.1 8 3 4 20 21 NA NA NA NA NA NA 14824 XM_044325079.1 0 16 3 1 25 NA NA NA NA NA NA 14825 XR_003825065.2 0 16 12 0 18 NA NA NA NA NA NA 14826 XM_044309496.1 14 7 28 6 0 NA NA NA NA NA NA 14827 XM_029323884.2 153 238 152 277 277 P13913 5.59e-32 Arylamine N-acetyltransferase, pineal gland isozyme NAT-10 (Arylamine acetylase) (EC 2.3.1.5) Gallus gallus (Chicken) NA GO:0004060 14828 XM_044312801.1 0 0 57 0 0 P45954 0 Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial (SBCAD) (EC 1.3.8.5) (2-methyl branched chain acyl-CoA dehydrogenase) (2-MEBCAD) (2-methylbutyryl-coenzyme A dehydrogenase) (2-methylbutyryl-CoA dehydrogenase) Homo sapiens (Human) fatty acid metabolic process [GO:0006631]; isoleucine catabolic process [GO:0006550] GO:0003853; GO:0003995; GO:0005739; GO:0005759; GO:0006550; GO:0006631; GO:0016937; GO:0042802; GO:0050660; GO:0102035 14829 XM_044326299.1 63 16 44 42 104 NA NA NA NA NA NA 14830 XM_044315408.1 11 3 0 0 11 NA NA NA NA NA NA 14831 XM_044313283.1 7 0 27 10 27 NA NA NA NA NA NA 14832 XM_029343887.2 221 213 326 824 568 Q6DHN0 8.47e-23 Transmembrane protein 53 Danio rerio (Zebrafish) (Brachydanio rerio) negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of ossification [GO:0030279]; negative regulation of osteoblast differentiation [GO:0045668]; regulation of nucleocytoplasmic transport [GO:0046822] GO:0005640; GO:0030279; GO:0030514; GO:0031965; GO:0045668; GO:0046822 14833 XM_044325387.1 468 499 783 753 103 Q9CYF5 3.84e-81 RCC1-like G exchanging factor-like protein (RCC1-like) (Williams-Beuren syndrome chromosomal region 16 protein homolog) Mus musculus (Mouse) mitochondrial fusion [GO:0008053]; positive regulation of mitochondrial translation [GO:0070131] GO:0005085; GO:0005739; GO:0005743; GO:0008053; GO:0019843; GO:0031966; GO:0070131 14834 XM_029342728.2 193 205 79 902 382 Q6ZNA5 6.19e-36 Ferric-chelate reductase 1 (EC 1.-.-.-) (Stromal cell-derived receptor 2) (SDR-2) Homo sapiens (Human) cellular iron ion homeostasis [GO:0006879] GO:0006879; GO:0016020; GO:0016722; GO:0046872 14835 XM_044309979.1 0 1 5 4 14 NA NA NA NA NA NA 14836 XR_006395428.1 17 13 1 34 5 NA NA NA NA NA NA 14837 XM_029352656.2 263 201 147 201 168 NA NA NA NA NA NA 14838 XM_029333308.2 826 754 323 1653 0 A0A1D5NSM8 4.51e-37 NA NA NA NA 14839 XM_044318307.1 114 17 0 12 0 Q9CUX1 4.46e-45 52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (THAP domain-containing protein 0) (THAP domain-containing protein 12) Mus musculus (Mouse) NA GO:0003677; GO:0005634; GO:0046872; GO:0046983 14840 XM_044325668.1 61 0 0 10 0 NA NA NA NA NA NA 14841 XM_029343460.2 1 7 0 0 0 NA NA NA NA NA NA 14842 XM_029358040.2 103 277 44 846 499 P31646 0 Sodium- and chloride-dependent GABA transporter 2 (GAT-2) (Solute carrier family 6 member 13) Rattus norvegicus (Rat) amino acid import across plasma membrane [GO:0089718]; creatine transmembrane transport [GO:0015881]; gamma-aminobutyric acid import [GO:0051939]; monocarboxylic acid transport [GO:0015718]; neurotransmitter transport [GO:0006836]; nitrogen compound transport [GO:0071705]; positive regulation of necrotic cell death [GO:0010940]; sodium ion transmembrane transport [GO:0035725]; taurine transport [GO:0015734] GO:0005283; GO:0005308; GO:0005332; GO:0005368; GO:0005369; GO:0005886; GO:0006836; GO:0008028; GO:0010940; GO:0015171; GO:0015185; GO:0015718; GO:0015734; GO:0015881; GO:0016323; GO:0035725; GO:0042165; GO:0043005; GO:0051939; GO:0071705; GO:0089718 14843 XM_029338580.2 122 0 0 0 24 Q13976 0 cGMP-dependent protein kinase 1 (cGK 1) (cGK1) (EC 2.7.11.12) (cGMP-dependent protein kinase I) (cGKI) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cGMP-mediated signaling [GO:0019934]; collateral sprouting [GO:0048668]; dendrite development [GO:0016358]; forebrain development [GO:0030900]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; negative regulation of vascular associated smooth muscle cell proliferation [GO:1904706]; neuron migration [GO:0001764]; protein phosphorylation [GO:0006468]; regulation of GTPase activity [GO:0043087]; relaxation of vascular associated smooth muscle [GO:0060087]; signal transduction [GO:0007165] GO:0001764; GO:0004672; GO:0004692; GO:0005246; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005886; GO:0006468; GO:0007165; GO:0016358; GO:0019934; GO:0030036; GO:0030553; GO:0030900; GO:0042802; GO:0043087; GO:0048668; GO:0060087; GO:0090331; GO:0106310; GO:1904706; GO:1904753 14844 XM_044322619.1 0 0 0 183 1 NA NA NA NA NA NA 14845 XM_029345512.2 114 97 27 73 75 NA NA NA NA NA NA 14846 XM_044325992.1 613 725 401 111 25 NA NA NA NA NA NA 14847 XM_029338714.2 0 0 0 0 34 NA NA NA NA NA NA 14848 XM_044327646.1 56 26 13 8 46 Q9H9S5 7.56e-142 Ribitol 5-phosphate transferase FKRP (EC 2.7.8.-) (Fukutin-related protein) (Ribitol-5-phosphate transferase) Homo sapiens (Human) protein O-linked mannosylation [GO:0035269]; protein processing [GO:0016485]; protein tetramerization [GO:0051262] GO:0000139; GO:0002162; GO:0005615; GO:0005654; GO:0005791; GO:0005794; GO:0005829; GO:0016485; GO:0016780; GO:0035269; GO:0042383; GO:0042802; GO:0046872; GO:0051262 14849 XM_029355878.2 256 28 55 78 85 NA NA NA NA NA NA 14850 XM_044321112.1 0 0 0 16 0 Q9R0N9 2.1e-34 Synaptotagmin-9 (Synaptotagmin IX) (SytIX) (Synaptotagmin V) Mus musculus (Mouse) calcium-dependent activation of synaptic vesicle fusion [GO:0099502]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of insulin secretion [GO:0050796]; vesicle-mediated transport [GO:0016192] GO:0000149; GO:0001786; GO:0005509; GO:0005544; GO:0005546; GO:0005886; GO:0014059; GO:0016192; GO:0017156; GO:0017158; GO:0019905; GO:0030141; GO:0030276; GO:0030667; GO:0030672; GO:0031045; GO:0042802; GO:0045956; GO:0050796; GO:0070382; GO:0071277; GO:0098686; GO:0099502 14851 XM_029339004.2 1605 812 539 842 643 A6NJI9 4.06e-26 Leucine-rich repeat-containing protein 72 Homo sapiens (Human) NA NA 14852 XM_044320414.1 34 0 0 0 0 NA NA NA NA NA NA 14853 XM_044312723.1 116 4 8 37 227 NA NA NA NA NA NA 14854 XM_029329243.2 153 122 149 174 168 P15206 4.73e-109 G2/mitotic-specific cyclin-B Marthasterias glacialis (Spiny starfish) cell division [GO:0051301]; mitotic cell cycle phase transition [GO:0044772] GO:0016538; GO:0044772; GO:0051301 14855 XM_044324431.1 42 24 0 17 22 NA NA NA NA NA NA 14856 XM_044319094.1 220 176 91 264 191 O62852 3.08e-96 Short transient receptor potential channel 5 (Rtrp5) (TrpC5) (Capacitative calcium entry channel 2) (CCE2) Oryctolagus cuniculus (Rabbit) neuron apoptotic process [GO:0051402]; phosphatidylserine exposure on apoptotic cell surface [GO:0070782] GO:0005262; GO:0005886; GO:0034704; GO:0051402; GO:0070679; GO:0070782 14857 XM_044310794.1 14 0 0 8 0 NA NA NA NA NA NA 14858 XM_029354135.2 3081 2504 1617 3186 2756 P23787 0 Transitional endoplasmic reticulum ATPase (TER ATPase) (EC 3.6.4.6) (15S Mg(2+)-ATPase p97 subunit) (p97) (Valosin-containing protein) (VCP) Xenopus laevis (African clawed frog) autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; interstrand cross-link repair [GO:0036297]; macroautophagy [GO:0016236]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of protein localization to chromatin [GO:1905634]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0000785; GO:0005524; GO:0005634; GO:0005737; GO:0005783; GO:0005829; GO:0006281; GO:0006302; GO:0006914; GO:0006974; GO:0008289; GO:0010494; GO:0010498; GO:0016236; GO:0016567; GO:0016887; GO:0019985; GO:0030433; GO:0032510; GO:0034605; GO:0035617; GO:0035861; GO:0036297; GO:0036503; GO:0042802; GO:0043161; GO:0044877; GO:0061857; GO:0097352; GO:1903843; GO:1905634 14859 XM_029341610.2 19422 13094 6094 15272 15029 A6QLI0 2.83e-22 Mammalian ependymin-related protein 1 (MERP-1) Bos taurus (Bovine) cell-matrix adhesion [GO:0007160]; myofibroblast contraction [GO:1990764] GO:0005509; GO:0005543; GO:0005576; GO:0005764; GO:0007160; GO:0042802; GO:0043202; GO:1905573; GO:1990764 14860 XR_006396676.1 0 26 0 14 12 NA NA NA NA NA NA 14861 XM_044326903.1 5 0 1 2 46 NA NA NA NA NA NA 14862 XR_006391618.1 11 0 0 0 23 P79384 0 Propionyl-CoA carboxylase beta chain, mitochondrial (PCCase subunit beta) (EC 6.4.1.3) (Propanoyl-CoA:carbon dioxide ligase subunit beta) Sus scrofa (Pig) short-chain fatty acid catabolic process [GO:0019626] GO:0004658; GO:0005524; GO:0005739; GO:0005759; GO:0019626 14863 XM_044313429.1 0 0 7 0 5 NA NA NA NA NA NA 14864 XM_044328713.1 110 69 70 74 174 NA NA NA NA NA NA 14865 XM_029325248.2 2 1 0 0 22 NA NA NA NA NA NA 14866 XM_044311929.1 17 0 0 1 22 Q96RW7 1.13e-33 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 14867 XM_044311929.1 17 0 0 1 22 Q96RW7 1.36e-30 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 14868 XM_044311929.1 17 0 0 1 22 Q96RW7 8.08e-28 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 14869 XM_044311929.1 17 0 0 1 22 Q96RW7 1.77e-27 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 14870 XM_044311929.1 17 0 0 1 22 Q96RW7 2.33e-27 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 14871 XM_044311929.1 17 0 0 1 22 Q96RW7 1.87e-25 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 14872 XM_044311929.1 17 0 0 1 22 Q96RW7 2.06e-25 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 14873 XM_044311929.1 17 0 0 1 22 Q96RW7 7.06e-24 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 14874 XM_044311929.1 17 0 0 1 22 Q96RW7 4.91e-23 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 14875 XM_044311929.1 17 0 0 1 22 Q96RW7 1.26e-22 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 14876 XM_044311929.1 17 0 0 1 22 Q96RW7 7.6e-22 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 14877 XM_044311929.1 17 0 0 1 22 Q96RW7 1.21e-21 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 14878 XM_044311929.1 17 0 0 1 22 Q96RW7 1.67e-21 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 14879 XM_044311929.1 17 0 0 1 22 Q96RW7 2.26e-21 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 14880 XM_044311929.1 17 0 0 1 22 Q96RW7 4.57e-21 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 14881 XM_044311929.1 17 0 0 1 22 Q96RW7 5.99e-21 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 14882 XM_044311929.1 17 0 0 1 22 Q96RW7 7.93e-21 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 14883 XM_029347462.2 22 7 11 5 10 NA NA NA NA NA NA 14884 XM_044307334.1 10 71 184 12 35 NA NA NA NA NA NA 14885 XM_044312620.1 43 45 11 80 49 NA NA NA NA NA NA 14886 XM_029347237.2 1774 1864 1484 911 586 NA NA NA NA NA NA 14887 XR_006394934.1 26 382 30 58 51 NA NA NA NA NA NA 14888 XM_029352044.2 126 114 83 100 56 NA NA NA NA NA NA 14889 XM_029353941.2 264 177 260 439 476 Q9H0J4 1.65e-41 Glutamine-rich protein 2 Homo sapiens (Human) cell projection assembly [GO:0030031]; flagellated sperm motility [GO:0030317]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059] GO:0005737; GO:0030031; GO:0030317; GO:0031965; GO:0036126; GO:2000059 14890 XM_029344305.2 30329 34711 35016 34740 13205 NA NA NA NA NA NA 14891 XM_044309345.1 11 11 2 21 21 NA NA NA NA NA NA 14892 XM_029357813.2 2424 1913 1667 1472 1970 Q3URY6 1.46e-117 Armadillo repeat-containing protein 2 Mus musculus (Mouse) cilium organization [GO:0044782]; sperm axoneme assembly [GO:0007288] GO:0007288; GO:0044782 14893 XR_003828628.2 1613 2161 1331 1439 889 NA NA NA NA NA NA 14894 XR_003826867.2 31 15 24 155 151 NA NA NA NA NA NA 14895 XM_044318348.1 105 48 6 1 66 NA NA NA NA NA NA 14896 XM_044315003.1 0 3 3 14 20 NA NA NA NA NA NA 14897 XR_006393525.1 15 15 0 5 2 NA NA NA NA NA NA 14898 XM_044329282.1 65 69 55 91 141 Q5VQ09 2.73e-34 Kinesin-like protein KIN-UB (Protein ARMADILLO REPEAT KINESIN2) Oryza sativa subsp. japonica (Rice) cytoskeleton-dependent intracellular transport [GO:0030705]; microtubule-based movement [GO:0007018] GO:0003777; GO:0005524; GO:0005737; GO:0005871; GO:0005874; GO:0007018; GO:0008017; GO:0008574; GO:0016887; GO:0030705 14899 XR_006395287.1 147 27 41 62 133 NA NA NA NA NA NA 14900 XM_044307535.1 0 0 0 33 66 Q1PSW8 1.57e-24 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (mLin41) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Mus musculus (Mouse) 3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to organic substance [GO:0071310]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA processing [GO:0035196]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; post-transcriptional regulation of gene expression [GO:0010608]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein metabolic process [GO:0051246]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0001843; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0010608; GO:0017148; GO:0021915; GO:0030371; GO:0035196; GO:0035198; GO:0035278; GO:0043161; GO:0051246; GO:0051865; GO:0060964; GO:0061158; GO:0061630; GO:0071310; GO:0072089; GO:2000177; GO:2000637 14901 XM_044318228.1 10 0 0 0 11 NA NA NA NA NA NA 14902 XM_029344877.2 649 343 259 707 679 NA NA NA NA NA NA 14903 XM_029344974.2 84 77 390 140 419 Q8NF64 7.15e-140 Zinc finger MIZ domain-containing protein 2 (PIAS-like protein Zimp7) Homo sapiens (Human) positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0005634; GO:0005654; GO:0005739; GO:0006357; GO:0008270; GO:0030374; GO:0043596; GO:0045944 14904 XM_029334073.2 16 63 0 0 0 Q7TQI7 0 Ankyrin repeat and BTB/POZ domain-containing protein 2 Mus musculus (Mouse) cellular response to toxic substance [GO:0097237] GO:0046982; GO:0097237 14905 XM_029338186.2 1033 543 423 851 831 O00423 9.32e-149 Echinoderm microtubule-associated protein-like 1 (EMAP-1) (HuEMAP-1) Homo sapiens (Human) brain development [GO:0007420]; hematopoietic progenitor cell differentiation [GO:0002244]; microtubule cytoskeleton organization [GO:0000226]; mitotic spindle organization [GO:0007052]; neuroblast proliferation [GO:0007405] GO:0000226; GO:0002244; GO:0005509; GO:0005829; GO:0005874; GO:0005875; GO:0007052; GO:0007405; GO:0007420; GO:0008017; GO:0015631; GO:0048471; GO:0097431; GO:1990023 14906 XM_029348030.2 2841 2287 1651 2156 1254 Q9D428 3.92e-48 Golgin subfamily A member 7B Mus musculus (Mouse) peptidyl-L-cysteine S-palmitoylation [GO:0018230]; protein targeting to membrane [GO:0006612] GO:0000139; GO:0002178; GO:0005886; GO:0006612; GO:0018230; GO:0019899 14907 XM_044309174.1 50 47 22 78 23 NA NA NA NA NA NA 14908 XM_029326395.2 241 435 293 383 368 Q6DC58 2.87e-24 Transmembrane protein 223 Danio rerio (Zebrafish) (Brachydanio rerio) mitochondrial cytochrome c oxidase assembly [GO:0033617]; nervous system development [GO:0007399] GO:0005739; GO:0005743; GO:0007399; GO:0033617; GO:0097177 14909 XM_029349594.2 4 0 0 11 6 Q09081 2.48e-73 Potassium voltage-gated channel subfamily A member 2 (KC22) (Voltage-gated potassium channel subunit Kv1.2) Oryctolagus cuniculus (Rabbit) neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233] GO:0005249; GO:0005251; GO:0005789; GO:0005886; GO:0008076; GO:0014059; GO:0019228; GO:0019233; GO:0021633; GO:0030027; GO:0030424; GO:0030425; GO:0031258; GO:0032809; GO:0033010; GO:0034765; GO:0042734; GO:0043194; GO:0043204; GO:0043679; GO:0044224; GO:0045188; GO:0051260; GO:0071805 14910 XM_044306748.1 2755 2617 1428 2271 1885 P61023 2.03e-70 Calcineurin B homologous protein 1 (Calcineurin B-like protein) (Calcium-binding protein CHP) (Calcium-binding protein p22) (EF-hand calcium-binding domain-containing protein p22) Rattus norvegicus (Rat) cellular response to acidic pH [GO:0071468]; cytoplasmic microtubule organization [GO:0031122]; membrane docking [GO:0022406]; membrane fusion [GO:0061025]; membrane organization [GO:0061024]; microtubule bundle formation [GO:0001578]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of phosphatase activity [GO:0010923]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of protein import into nucleus [GO:0042308]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of phospholipid biosynthetic process [GO:0071073]; positive regulation of protein glycosylation [GO:0060050]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein transport [GO:0051222]; positive regulation of sodium:proton antiporter activity [GO:0032417]; protein complex oligomerization [GO:0051259]; protein export from nucleus [GO:0006611]; protein stabilization [GO:0050821]; proton transmembrane transport [GO:1902600]; regulation of intracellular pH [GO:0051453]; regulation of neuron death [GO:1901214]; sodium ion transmembrane transport [GO:0035725]; vesicle fusion [GO:0006906]; vesicle targeting [GO:0006903] GO:0000139; GO:0001578; GO:0001933; GO:0004860; GO:0005509; GO:0005634; GO:0005737; GO:0005783; GO:0005793; GO:0005829; GO:0005886; GO:0006469; GO:0006611; GO:0006903; GO:0006906; GO:0008017; GO:0008047; GO:0010923; GO:0015385; GO:0015630; GO:0019900; GO:0022406; GO:0030133; GO:0031122; GO:0031397; GO:0031953; GO:0032088; GO:0032417; GO:0035725; GO:0042308; GO:0045121; GO:0048306; GO:0050821; GO:0051222; GO:0051259; GO:0051453; GO:0060050; GO:0061024; GO:0061025; GO:0070885; GO:0071073; GO:0071468; GO:0090314; GO:1901214; GO:1902600; GO:1990351 14911 XM_029333880.2 1814 1562 1677 1881 1966 F8WK50 0 NA NA NA NA 14912 XM_029335610.2 135 87 90 81 183 Q99575 6.86e-136 Ribonucleases P/MRP protein subunit POP1 (hPOP1) Homo sapiens (Human) RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; tRNA 5'-leader removal [GO:0001682]; tRNA catabolic process [GO:0016078]; tRNA processing [GO:0008033] GO:0000172; GO:0001682; GO:0003723; GO:0004526; GO:0005615; GO:0005654; GO:0005655; GO:0005730; GO:0008033; GO:0016078; GO:0030681; GO:0033204; GO:0090502 14913 XM_029357589.2 105 258 194 192 159 NA NA NA NA NA NA 14914 XM_044318362.1 108 135 155 18 254 NA NA NA NA NA NA 14915 XM_029350492.2 508 0 235 389 377 Q5C9Z4 6.93e-159 Nucleolar MIF4G domain-containing protein 1 (SGD1 homolog) Homo sapiens (Human) hair follicle maturation [GO:0048820]; ribosomal small subunit biogenesis [GO:0042274] GO:0003723; GO:0005730; GO:0042274; GO:0048820 14916 XM_029348090.2 3582 1475 1791 4367 3517 P98064 8.11e-148 Mannan-binding lectin serine protease 1 (EC 3.4.21.-) (Complement factor MASP-3) (Complement-activating component of Ra-reactive factor) (Mannose-binding lectin-associated serine protease 1) (MASP-1) (Mannose-binding protein-associated serine protease) (Ra-reactive factor serine protease p100) (RaRF) (Serine protease 5) [Cleaved into: Mannan-binding lectin serine protease 1 heavy chain; Mannan-binding lectin serine protease 1 light chain] Mus musculus (Mouse) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation, lectin pathway [GO:0001867]; negative regulation of complement activation [GO:0045916]; positive regulation of opsonization [GO:1903028]; proteolysis [GO:0006508] GO:0001867; GO:0002752; GO:0004252; GO:0005509; GO:0005615; GO:0005654; GO:0005829; GO:0006508; GO:0008233; GO:0042802; GO:0042803; GO:0045916; GO:0048306; GO:1903028; GO:1905370 14917 XM_029349620.2 12 13 1 10 32 NA NA NA NA NA NA 14918 XM_044324795.1 269 158 250 414 126 P35546 5e-81 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; anatomical structure morphogenesis [GO:0009653]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006919; GO:0007156; GO:0007158; GO:0007169; GO:0007399; GO:0009410; GO:0009653; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030182; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0098797; GO:2001241 14919 XR_006396937.1 163 107 147 124 212 NA NA NA NA NA NA 14920 XM_029333412.2 100 43 57 29 0 Q6PEM8 6.87e-44 Proton-coupled folate transporter (Heme carrier protein 1) (PCFT/HCP1) (Solute carrier family 46 member 1) Mus musculus (Mouse) folate import across plasma membrane [GO:1904447]; folate transmembrane transport [GO:0098838]; folic acid transport [GO:0015884]; heme transport [GO:0015886]; proton transmembrane transport [GO:1902600]; transmembrane transport [GO:0055085] GO:0005542; GO:0005737; GO:0005768; GO:0005886; GO:0008517; GO:0010008; GO:0015078; GO:0015232; GO:0015293; GO:0015350; GO:0015884; GO:0015886; GO:0016020; GO:0016323; GO:0016324; GO:0022857; GO:0031526; GO:0055085; GO:0098838; GO:0140211; GO:1902600; GO:1904447 14921 XR_003823276.2 1 20 82 5 9 NA NA NA NA NA NA 14922 XM_029330076.2 79 65 0 12 21 Q14155 2.89e-154 Rho guanine nucleotide exchange factor 7 (Beta-Pix) (COOL-1) (PAK-interacting exchange factor beta) (p85) Homo sapiens (Human) ephrin receptor signaling pathway [GO:0048013]; focal adhesion assembly [GO:0048041]; Golgi organization [GO:0007030]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; negative regulation of microtubule nucleation [GO:1905833]; nervous system development [GO:0007399]; positive regulation of apoptotic process [GO:0043065]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of GTPase activity [GO:0043547]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of GTP binding [GO:1904424]; signal transduction [GO:0007165] GO:0001726; GO:0005085; GO:0005737; GO:0005813; GO:0005829; GO:0005925; GO:0005938; GO:0007030; GO:0007165; GO:0007399; GO:0010763; GO:0019901; GO:0030027; GO:0030032; GO:0032991; GO:0035556; GO:0043005; GO:0043015; GO:0043025; GO:0043065; GO:0043547; GO:0048013; GO:0048041; GO:0097431; GO:0098794; GO:1900026; GO:1904424; GO:1905833; GO:2000394 14923 XM_029334731.2 219 242 164 327 251 NA NA NA NA NA NA 14924 XM_029337067.2 698 321 302 778 898 Q9EPW2 7.51e-42 Krueppel-like factor 15 (Cardiovascular Krueppel-like factor) Mus musculus (Mouse) cardiac muscle hypertrophy in response to stress [GO:0014898]; cellular glucose homeostasis [GO:0001678]; cellular response to peptide [GO:1901653]; glial cell differentiation [GO:0010001]; negative regulation of peptidyl-lysine acetylation [GO:2000757]; podocyte differentiation [GO:0072112]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of glucose import [GO:0046326]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression [GO:0010468]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of Wnt signaling pathway [GO:0030111]; response to insulin [GO:0032868] GO:0000976; GO:0000977; GO:0000978; GO:0000981; GO:0001228; GO:0001678; GO:0003677; GO:0003700; GO:0005634; GO:0005654; GO:0006357; GO:0010001; GO:0010468; GO:0014898; GO:0016607; GO:0030111; GO:0032868; GO:0043231; GO:0045893; GO:0045944; GO:0046326; GO:0046872; GO:0072112; GO:1901653; GO:1990837; GO:2000757 14925 XM_044312221.1 76 34 49 56 85 NA NA NA NA NA NA 14926 XM_044324488.1 0 0 8 1 15 NA NA NA NA NA NA 14927 XM_044325491.1 0 21 51 54 0 NA NA NA NA NA NA 14928 XM_044326830.1 17 39 35 36 48 NA NA NA NA NA NA 14929 XM_044318234.1 22 4 17 17 17 Q9C040 8.64e-77 Tripartite motif-containing protein 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRIM2) (RING finger protein 86) (RING-type E3 ubiquitin transferase TRIM2) Homo sapiens (Human) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; regulation of neuron apoptotic process [GO:0043523] GO:0000209; GO:0004842; GO:0005737; GO:0008270; GO:0043161; GO:0043523; GO:0061630 14930 XM_044318234.1 22 4 17 17 17 Q9C040 9.01e-23 Tripartite motif-containing protein 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRIM2) (RING finger protein 86) (RING-type E3 ubiquitin transferase TRIM2) Homo sapiens (Human) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; regulation of neuron apoptotic process [GO:0043523] GO:0000209; GO:0004842; GO:0005737; GO:0008270; GO:0043161; GO:0043523; GO:0061630 14931 XM_029343723.2 7 0 13 11 3 NA NA NA NA NA NA 14932 XM_029343925.2 33 65 0 192 209 E7F654 1.12e-64 NA NA NA NA 14933 XM_044312905.1 16 37 73 55 46 Q9WVM6 6.32e-33 Tolloid-like protein 2 (EC 3.4.24.-) Mus musculus (Mouse) cell differentiation [GO:0030154]; dorsal/ventral pattern formation [GO:0009953]; negative regulation of skeletal muscle tissue growth [GO:0048632]; protein processing [GO:0016485] GO:0004222; GO:0005509; GO:0005615; GO:0008270; GO:0009953; GO:0016485; GO:0030154; GO:0048632 14934 XM_044312905.1 16 37 73 55 46 Q9WVM6 6.94e-28 Tolloid-like protein 2 (EC 3.4.24.-) Mus musculus (Mouse) cell differentiation [GO:0030154]; dorsal/ventral pattern formation [GO:0009953]; negative regulation of skeletal muscle tissue growth [GO:0048632]; protein processing [GO:0016485] GO:0004222; GO:0005509; GO:0005615; GO:0008270; GO:0009953; GO:0016485; GO:0030154; GO:0048632 14935 XR_006391934.1 72 0 0 78 18 NA NA NA NA NA NA 14936 XM_029345169.2 2326 2229 2443 2928 3311 Q8N695 3.52e-132 Sodium-coupled monocarboxylate transporter 1 (Apical iodide transporter) (Electrogenic sodium monocarboxylate cotransporter) (Sodium iodide-related cotransporter) (Solute carrier family 5 member 8) Homo sapiens (Human) apoptotic process [GO:0006915]; ion transport [GO:0006811]; NAD biosynthesis via nicotinamide riboside salvage pathway [GO:0034356]; propanoate transport [GO:0015730]; sodium ion transport [GO:0006814] GO:0005343; GO:0005886; GO:0006811; GO:0006814; GO:0006915; GO:0008028; GO:0015129; GO:0015293; GO:0015552; GO:0015730; GO:0016324; GO:0022803; GO:0034356; GO:0070062; GO:0140161 14937 XM_029333128.2 2048 919 1299 954 1209 Q9EPB1 1.95e-153 Dipeptidyl peptidase 2 (EC 3.4.14.2) (Dipeptidyl aminopeptidase II) (Dipeptidyl peptidase 7) (Dipeptidyl peptidase II) (DPP II) (Quiescent cell proline dipeptidase) Rattus norvegicus (Rat) lysosomal protein catabolic process [GO:1905146]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508] GO:0004177; GO:0005576; GO:0005764; GO:0005829; GO:0006508; GO:0008236; GO:0008239; GO:0030163; GO:0031410; GO:0031982; GO:1905146 14938 XM_029329412.2 167 48 19 200 195 B5DF45 1.79e-100 TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6) Rattus norvegicus (Rat) activation of NF-kappaB-inducing kinase activity [GO:0007250]; activation of protein kinase activity [GO:0032147]; animal organ morphogenesis [GO:0009887]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; bone remodeling [GO:0046849]; bone resorption [GO:0045453]; cell development [GO:0048468]; cellular response to cytokine stimulus [GO:0071345]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-17-mediated signaling pathway [GO:0097400]; JNK cascade [GO:0007254]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin production [GO:0002637]; response to interleukin-1 [GO:0070555]; response to ischemia [GO:0002931]; signal transduction [GO:0007165]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000122; GO:0000209; GO:0001503; GO:0001701; GO:0001843; GO:0002637; GO:0002726; GO:0002931; GO:0004842; GO:0005164; GO:0005634; GO:0005737; GO:0005811; GO:0005829; GO:0005886; GO:0005938; GO:0006955; GO:0006974; GO:0007165; GO:0007249; GO:0007250; GO:0007254; GO:0008270; GO:0009887; GO:0009898; GO:0016567; GO:0019221; GO:0019886; GO:0019901; GO:0030316; GO:0031435; GO:0031624; GO:0031625; GO:0031666; GO:0031996; GO:0032147; GO:0032735; GO:0032743; GO:0032755; GO:0032813; GO:0032991; GO:0033209; GO:0035631; GO:0042088; GO:0042102; GO:0042475; GO:0042802; GO:0042826; GO:0042981; GO:0043011; GO:0043122; GO:0043123; GO:0043422; GO:0043507; GO:0045453; GO:0045672; GO:0045892; GO:0045944; GO:0046330; GO:0046849; GO:0047485; GO:0048468; GO:0048471; GO:0048661; GO:0050852; GO:0051091; GO:0051092; GO:0051865; GO:0061630; GO:0070498; GO:0070534; GO:0070555; GO:0071222; GO:0071345; GO:0097400; GO:1901224; GO:1904996; GO:2000679 14939 XM_044313057.1 136 0 18 0 0 O43603 2.15e-21 Galanin receptor type 2 (GAL2-R) (GALR-2) Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell surface receptor signaling pathway [GO:0007166]; feeding behavior [GO:0007631]; galanin-activated signaling pathway [GO:0090663]; inositol phosphate metabolic process [GO:0043647]; learning or memory [GO:0007611]; muscle contraction [GO:0006936]; negative regulation of adenylate cyclase activity [GO:0007194]; neuron projection development [GO:0031175]; neuropeptide signaling pathway [GO:0007218]; phosphatidylinositol metabolic process [GO:0046488]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of large conductance calcium-activated potassium channel activity [GO:1902608]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0004966; GO:0005886; GO:0005929; GO:0006936; GO:0007166; GO:0007188; GO:0007189; GO:0007194; GO:0007200; GO:0007204; GO:0007218; GO:0007611; GO:0007631; GO:0008528; GO:0016020; GO:0017046; GO:0031175; GO:0042923; GO:0043647; GO:0045944; GO:0046488; GO:0090663; GO:1902608 14940 XM_044315693.1 148 151 68 40 109 NA NA NA NA NA NA 14941 XM_029337562.2 10 0 0 4 1 NA NA NA NA NA NA 14942 XM_029355798.2 86 53 32 17 42 NA NA NA NA NA NA 14943 XM_029338140.2 10 15 6 27 27 Q14112 1.09e-27 Nidogen-2 (NID-2) (Osteonidogen) Homo sapiens (Human) basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160] GO:0005201; GO:0005509; GO:0005518; GO:0005576; GO:0005604; GO:0005615; GO:0005886; GO:0007155; GO:0007160; GO:0062023; GO:0070062; GO:0071711 14944 XM_029336901.2 409 331 285 320 207 NA NA NA NA NA NA 14945 XM_044309323.1 57 1 91 51 292 NA NA NA NA NA NA 14946 XR_003828445.2 3648 2713 2391 3342 3982 NA NA NA NA NA NA 14947 XM_044310742.1 58 1 0 1 76 NA NA NA NA NA NA 14948 XM_029353922.2 67 34 28 115 140 Q29611 1.37e-35 Battenin (Protein CLN3) Canis lupus familiaris (Dog) (Canis familiaris) amyloid precursor protein catabolic process [GO:0042987]; autophagosome-lysosome fusion [GO:0061909]; cellular water homeostasis [GO:0009992]; glycerophospholipid biosynthetic process [GO:0046474]; glycolipid transport [GO:0046836]; Golgi to lysosome transport [GO:0090160]; L-arginine transmembrane transport [GO:1903826]; learning or memory [GO:0007611]; lysosomal lumen acidification [GO:0007042]; lysosomal lumen pH elevation [GO:0035752]; lysosomal protein catabolic process [GO:1905146]; negative regulation of apoptotic process [GO:0043066]; phagosome-lysosome docking [GO:0090384]; phagosome-lysosome fusion [GO:0090385]; plasma membrane raft organization [GO:0044857]; positive regulation of caveolin-mediated endocytosis [GO:2001288]; positive regulation of Golgi to plasma membrane protein transport [GO:0042998]; positive regulation of pinocytosis [GO:0048549]; receptor-mediated endocytosis [GO:0006898]; regulation of arginine biosynthetic process [GO:1900079]; regulation of autophagosome maturation [GO:1901096]; regulation of cellular response to osmotic stress [GO:0106049]; regulation of cytoskeleton organization [GO:0051493]; regulation of fibroblast migration [GO:0010762]; regulation of modification of synaptic structure [GO:1905244]; regulation of phagosome maturation [GO:1905162]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of protein processing [GO:0070613]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic transmission, GABAergic [GO:0032228]; regulation of synaptic transmission, glutamatergic [GO:0051966]; renal potassium excretion [GO:0036359]; vesicle transport along microtubule [GO:0047496] GO:0000139; GO:0005634; GO:0005737; GO:0005764; GO:0005765; GO:0005769; GO:0005770; GO:0005783; GO:0005789; GO:0005794; GO:0005795; GO:0005802; GO:0005829; GO:0005886; GO:0005901; GO:0006898; GO:0007042; GO:0007611; GO:0008021; GO:0009992; GO:0010762; GO:0016020; GO:0031901; GO:0032228; GO:0035752; GO:0036359; GO:0042987; GO:0042998; GO:0043005; GO:0043066; GO:0044754; GO:0044857; GO:0045121; GO:0046474; GO:0046836; GO:0047496; GO:0048172; GO:0048549; GO:0051493; GO:0051861; GO:0051966; GO:0055037; GO:0061909; GO:0070613; GO:0090160; GO:0090384; GO:0090385; GO:0106049; GO:0120146; GO:1900079; GO:1901096; GO:1903076; GO:1903826; GO:1905146; GO:1905162; GO:1905244; GO:2001288 14949 XM_029357501.2 104 0 0 0 0 P23824 7.18e-70 GATA-binding factor 2 (GATA-2) (Transcription factor NF-E1b) Gallus gallus (Chicken) cell fate commitment [GO:0045165]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of angiogenesis [GO:0045766]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000122; GO:0000978; GO:0000981; GO:0001223; GO:0005634; GO:0008270; GO:0045165; GO:0045766; GO:0045944; GO:1902895 14950 XM_029346493.2 543 484 252 818 52 Q9CS00 0 Splicing factor Cactin Mus musculus (Mouse) cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; innate immune response [GO:0045087]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339] GO:0000398; GO:0001933; GO:0005634; GO:0005654; GO:0005681; GO:0005737; GO:0005829; GO:0016607; GO:0031665; GO:0032088; GO:0032688; GO:0032717; GO:0032720; GO:0034122; GO:0043124; GO:0045087; GO:0045292; GO:0045824; GO:0060339; GO:0071013; GO:0071222; GO:0071347; GO:0071356 14951 XR_006396881.1 3 19 0 5 27 NA NA NA NA NA NA 14952 XM_044312853.1 238 59 94 225 198 A4IF93 8.22e-152 TBCC domain-containing protein 1 Bos taurus (Bovine) maintenance of centrosome location [GO:0051661]; maintenance of Golgi location [GO:0051684]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360] GO:0005737; GO:0008360; GO:0030334; GO:0031616; GO:0051661; GO:0051684 14953 XM_029344008.2 14436 21699 10731 14221 11834 P47830 2.87e-64 60S ribosomal protein L27a (L22) Xenopus laevis (African clawed frog) translation [GO:0006412] GO:0003735; GO:0005737; GO:0006412; GO:0015934 14954 XM_044318436.1 174 34 235 60 1049 NA NA NA NA NA NA 14955 XM_029346242.2 314 136 91 104 308 P61593 2.49e-45 Microcephalin Pan troglodytes (Chimpanzee) cerebral cortex development [GO:0021987]; mitotic cell cycle [GO:0000278] GO:0000278; GO:0005737; GO:0005815; GO:0021987 14956 XM_044321793.1 39 72 293 221 17 Q66IB8 5.96e-43 UPF0538 protein C2orf76 homolog Danio rerio (Zebrafish) (Brachydanio rerio) NA NA 14957 XM_029349805.2 161 53 66 98 61 NA NA NA NA NA NA 14958 XM_029342499.2 11 0 3 33 18 P55023 9.43e-23 Tyrosinase (EC 1.14.18.1) (Monophenol monooxygenase) Streptomyces lincolnensis melanin biosynthetic process [GO:0042438] GO:0004503; GO:0042438; GO:0046872 14959 XM_044308961.1 0 148 0 8 2 NA NA NA NA NA NA 14960 XM_044311818.1 8 0 15 13 20 Q9M2U3 4.28e-41 Protein ALP1-like (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) NA GO:0000118; GO:0004518; GO:0046872 14961 XM_044322411.1 233 247 221 215 93 Q5RFP4 1.9e-52 Zinc finger protein OZF (Only zinc finger protein) (Zinc finger protein 146) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 14962 XM_044322411.1 233 247 221 215 93 Q5RFP4 2.17e-44 Zinc finger protein OZF (Only zinc finger protein) (Zinc finger protein 146) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 14963 XR_006394437.1 353 198 107 486 188 NA NA NA NA NA NA 14964 XM_044308365.1 22 13 11 37 8 NA NA NA NA NA NA 14965 XM_029349232.2 11480 17548 6202 14375 12311 Q9R1S4 1.81e-25 X-box-binding protein 1 (Hepatocarcinogenesis-related transcription factor) (HTF) [Cleaved into: X-box-binding protein 1, cytoplasmic form; X-box-binding protein 1, luminal form] Rattus norvegicus (Rat) adipose tissue development [GO:0060612]; angiogenesis [GO:0001525]; cellular response to amino acid stimulus [GO:0071230]; cellular response to antibiotic [GO:0071236]; cellular response to fluid shear stress [GO:0071498]; cellular response to fructose stimulus [GO:0071332]; cellular response to glucose starvation [GO:0042149]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-4 [GO:0071353]; cellular response to laminar fluid shear stress [GO:0071499]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient [GO:0031670]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular triglyceride homeostasis [GO:0035356]; cholesterol homeostasis [GO:0042632]; DNA-templated transcription [GO:0006351]; endoplasmic reticulum unfolded protein response [GO:0030968]; endothelial cell proliferation [GO:0001935]; epithelial cell maturation [GO:0002070]; epithelial cell maturation involved in salivary gland development [GO:0060691]; exocrine pancreas development [GO:0031017]; fatty acid homeostasis [GO:0055089]; glandular epithelial cell maturation [GO:0002071]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; liver development [GO:0001889]; muscle organ development [GO:0007517]; negative regulation of apoptotic process [GO:0043066]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of myotube differentiation [GO:0010832]; neuron development [GO:0048666]; positive regulation of angiogenesis [GO:0045766]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of hepatocyte proliferation [GO:2000347]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of lactation [GO:1903489]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of plasma cell differentiation [GO:1900100]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response [GO:0006990]; positive regulation of vascular wound healing [GO:0035470]; protein destabilization [GO:0031648]; regulation of autophagy [GO:0010506]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; response to electrical stimulus [GO:0051602]; response to endoplasmic reticulum stress [GO:0034976]; response to insulin-like growth factor stimulus [GO:1990418]; response to xenobiotic stimulus [GO:0009410]; serotonin secretion, neurotransmission [GO:0060096]; sterol homeostasis [GO:0055092]; transcription by RNA polymerase II [GO:0006366]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000976; GO:0000977; GO:0000978; GO:0000981; GO:0000987; GO:0001525; GO:0001889; GO:0001935; GO:0002070; GO:0002071; GO:0002639; GO:0003677; GO:0003700; GO:0005634; GO:0005737; GO:0005783; GO:0005789; GO:0006351; GO:0006355; GO:0006357; GO:0006366; GO:0006511; GO:0006990; GO:0007517; GO:0008284; GO:0009410; GO:0010506; GO:0010832; GO:0030335; GO:0030968; GO:0031017; GO:0031490; GO:0031648; GO:0031670; GO:0032755; GO:0032869; GO:0034976; GO:0035356; GO:0035470; GO:0035924; GO:0036312; GO:0042149; GO:0042632; GO:0042802; GO:0042826; GO:0043066; GO:0043565; GO:0044389; GO:0045348; GO:0045579; GO:0045582; GO:0045600; GO:0045766; GO:0045944; GO:0046982; GO:0048666; GO:0051602; GO:0055089; GO:0055092; GO:0060096; GO:0060612; GO:0060691; GO:0070059; GO:0071222; GO:0071230; GO:0071236; GO:0071332; GO:0071333; GO:0071353; GO:0071375; GO:0071498; GO:0071499; GO:0090575; GO:0098793; GO:1900100; GO:1900103; GO:1902236; GO:1903489; GO:1990418; GO:1990830; GO:1990837; GO:2000347 14966 XM_029357237.2 46 24 36 17 6 NA NA NA NA NA NA 14967 XR_006398139.1 34 31 13 64 46 NA NA NA NA NA NA 14968 XM_029331520.2 164 91 98 150 143 Q9D565 0 WD repeat-containing protein 64 Mus musculus (Mouse) NA NA 14969 XR_006396392.1 4 0 9 47 12 NA NA NA NA NA NA 14970 XM_029332567.2 691 582 459 461 396 O95671 1.36e-67 Probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein [Includes: dTTP/UTP pyrophosphatase (dTTPase/UTPase) (EC 3.6.1.9) (Nucleoside triphosphate pyrophosphatase) (Nucleotide pyrophosphatase) (Nucleotide PPase); N-acetylserotonin O-methyltransferase-like protein (ASMTL) (EC 2.1.1.-)] Homo sapiens (Human) methylation [GO:0032259]; nucleotide metabolic process [GO:0009117] GO:0005829; GO:0008171; GO:0009117; GO:0032259; GO:0036218; GO:0036221; GO:0047429 14971 XM_029352412.2 505 350 544 617 1139 Q2T9I5 1.39e-21 RNA-binding protein 26 (RNA-binding motif protein 26) Xenopus laevis (African clawed frog) mRNA processing [GO:0006397] GO:0003723; GO:0005634; GO:0006397; GO:0046872 14972 XM_029352815.2 1 12 0 1 8 Q09575 1.59e-55 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 14973 XR_006392399.1 10 16 13 5 20 NA NA NA NA NA NA 14974 XM_044321462.1 648 0 318 50 486 Q0P4F7 0 Medium-chain acyl-CoA ligase ACSF2, mitochondrial (EC 6.2.1.2) Danio rerio (Zebrafish) (Brachydanio rerio) fatty acid metabolic process [GO:0006631] GO:0005524; GO:0005739; GO:0006631; GO:0031956; GO:0047760 14975 XR_006392975.1 41 2 25 5 151 NA NA NA NA NA NA 14976 XM_044322061.1 0 37 50 0 0 Q7RTR2 5.28e-66 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 14977 XM_044322061.1 0 37 50 0 0 Q7RTR2 7.33e-65 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 14978 XM_044322061.1 0 37 50 0 0 Q7RTR2 8.94e-41 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 14979 XM_029346474.2 86 72 56 55 97 NA NA NA NA NA NA 14980 XM_044320312.1 38 48 24 4 0 O70244 6.96e-70 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 14981 XM_044320312.1 38 48 24 4 0 O70244 7.72e-66 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 14982 XM_044320312.1 38 48 24 4 0 O70244 3.03e-63 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 14983 XM_044320312.1 38 48 24 4 0 O70244 7.76e-61 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 14984 XM_044320312.1 38 48 24 4 0 O70244 2.6e-59 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 14985 XM_044320312.1 38 48 24 4 0 O70244 9.17e-55 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 14986 XM_044320312.1 38 48 24 4 0 O70244 3.35e-50 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 14987 XM_044320312.1 38 48 24 4 0 O70244 4.4e-48 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 14988 XM_044320312.1 38 48 24 4 0 O70244 7.66e-47 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 14989 XM_044322974.1 72 16 144 97 98 Q9H3L0 2.19e-68 Cobalamin trafficking protein CblD (CblD) (Methylmalonic aciduria and homocystinuria type D protein, mitochondrial) Homo sapiens (Human) cobalamin metabolic process [GO:0009235] GO:0005737; GO:0005739; GO:0005829; GO:0009235 14990 XM_029334111.2 0 50 0 14 0 A6H8T2 9.52e-77 Dynein axonemal intermediate chain 7 Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005930; GO:0008017; GO:0048487 14991 XM_029334111.2 0 50 0 14 0 A6H8T2 4.93e-36 Dynein axonemal intermediate chain 7 Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005930; GO:0008017; GO:0048487 14992 XM_044315426.1 35 0 6 88 22 NA NA NA NA NA NA 14993 XR_006391461.1 15 0 11 10 10 NA NA NA NA NA NA 14994 XM_044327064.1 1204 597 611 949 969 B2GUB3 3.84e-178 Tubulin tyrosine ligase 3 (EC 6.3.2.-) (Tubulin--tyrosine ligase protein 3) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) protein polyglycylation [GO:0018094] GO:0005524; GO:0005737; GO:0005874; GO:0018094; GO:0031514; GO:0046872; GO:0070736 14995 XR_003825654.2 118 149 28 186 87 NA NA NA NA NA NA 14996 XM_044314868.1 52 24 22 171 66 NA NA NA NA NA NA 14997 XM_029336568.2 33 113 0 91 0 P63079 3.08e-82 Gamma-aminobutyric acid receptor subunit beta-3 (GABA(A) receptor subunit beta-3) Rattus norvegicus (Rat) brain development [GO:0007420]; cellular response to histamine [GO:0071420]; cellular response to zinc ion [GO:0071294]; cerebellum development [GO:0021549]; chemical synaptic transmission [GO:0007268]; chemical synaptic transmission, postsynaptic [GO:0099565]; chloride transmembrane transport [GO:1902476]; circadian sleep/wake cycle, REM sleep [GO:0042747]; cochlea development [GO:0090102]; exploration behavior [GO:0035640]; gamma-aminobutyric acid signaling pathway [GO:0007214]; hard palate development [GO:0060022]; inhibitory postsynaptic potential [GO:0060080]; inhibitory synapse assembly [GO:1904862]; inner ear receptor cell development [GO:0060119]; innervation [GO:0060384]; ion transmembrane transport [GO:0034220]; learning [GO:0007612]; memory [GO:0007613]; motor behavior [GO:0061744]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; nervous system development [GO:0007399]; nervous system process [GO:0050877]; neuron development [GO:0048666]; regulation of membrane potential [GO:0042391]; regulation of neuron apoptotic process [GO:0043523]; regulation of postsynaptic membrane potential [GO:0060078]; reproductive behavior [GO:0019098]; response to anesthetic [GO:0072347]; response to xenobiotic stimulus [GO:0009410]; roof of mouth development [GO:0060021]; sensory perception of sound [GO:0007605]; signal transduction [GO:0007165]; social behavior [GO:0035176]; synaptic transmission, GABAergic [GO:0051932] GO:0004890; GO:0005216; GO:0005231; GO:0005254; GO:0005886; GO:0007165; GO:0007214; GO:0007268; GO:0007399; GO:0007420; GO:0007605; GO:0007612; GO:0007613; GO:0009410; GO:0009986; GO:0019098; GO:0021549; GO:0022851; GO:0030594; GO:0030659; GO:0034220; GO:0034707; GO:0035176; GO:0035612; GO:0035640; GO:0042391; GO:0042747; GO:0042802; GO:0043005; GO:0043195; GO:0043523; GO:0043524; GO:0045202; GO:0045211; GO:0048666; GO:0050877; GO:0051932; GO:0060021; GO:0060022; GO:0060077; GO:0060078; GO:0060080; GO:0060119; GO:0060384; GO:0061744; GO:0071294; GO:0071420; GO:0072347; GO:0090102; GO:0098982; GO:0099565; GO:0099634; GO:1901215; GO:1902476; GO:1902711; GO:1904315; GO:1904862 14998 XM_029350575.2 0 86 108 0 0 Q1ZZH1 4.64e-171 Metabotropic glutamate receptor 3 (mGluR3) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0004930; GO:0005886; GO:0008066 14999 XM_044317294.1 616 497 585 440 840 Q155U0 0 Vacuolar protein sorting-associated protein 51 homolog (Protein fat-free) Danio rerio (Zebrafish) (Brachydanio rerio) endocytic recycling [GO:0032456]; Golgi organization [GO:0007030]; Golgi vesicle transport [GO:0048193]; lipid digestion [GO:0044241]; lipid transport [GO:0006869]; lysosomal transport [GO:0007041]; protein transport [GO:0015031]; regulation of phospholipase activity [GO:0010517]; retrograde transport, endosome to Golgi [GO:0042147] GO:0000938; GO:0005829; GO:0006869; GO:0007030; GO:0007041; GO:0010517; GO:0015031; GO:0016020; GO:0031267; GO:0032456; GO:0042147; GO:0044241; GO:0048193; GO:0055037; GO:1990745 15000 XR_006395816.1 31 30 14 29 30 NA NA NA NA NA NA 15001 XM_044316381.1 0 0 11 8 1 NA NA NA NA NA NA 15002 XR_006393926.1 22 52 5 92 47 NA NA NA NA NA NA 15003 XM_029348825.2 471 337 291 386 505 D4A615 1e-98 Tonsoku-like protein (Inhibitor of kappa B-related protein) (I-kappa-B-related protein) (IkappaBR) (NF-kappa-B inhibitor-like protein 2) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2) Rattus norvegicus (Rat) double-strand break repair via homologous recombination [GO:0000724]; replication fork processing [GO:0031297] GO:0000724; GO:0005662; GO:0005737; GO:0016604; GO:0031297; GO:0035101; GO:0035861; GO:0042393; GO:0042555; GO:0043596; GO:0140566 15004 XM_029348825.2 471 337 291 386 505 D4A615 1.19e-60 Tonsoku-like protein (Inhibitor of kappa B-related protein) (I-kappa-B-related protein) (IkappaBR) (NF-kappa-B inhibitor-like protein 2) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2) Rattus norvegicus (Rat) double-strand break repair via homologous recombination [GO:0000724]; replication fork processing [GO:0031297] GO:0000724; GO:0005662; GO:0005737; GO:0016604; GO:0031297; GO:0035101; GO:0035861; GO:0042393; GO:0042555; GO:0043596; GO:0140566 15005 XM_029335613.2 75 88 51 89 88 NA NA NA NA NA NA 15006 XR_006391665.1 45 14 5 12 13 NA NA NA NA NA NA 15007 XR_006393425.1 66 15 28 100 19 NA NA NA NA NA NA 15008 XM_029339294.2 0 18 42 0 0 NA NA NA NA NA NA 15009 XM_044317340.1 242 81 11 367 177 NA NA NA NA NA NA 15010 XM_029350306.2 1453 1183 863 1089 1100 Q9P278 3.78e-96 Folliculin-interacting protein 2 (FNIP1-like protein) (O6-methylguanine-induced apoptosis 1 protein) Homo sapiens (Human) intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein-containing complex assembly [GO:0031334]; protein phosphorylation [GO:0006468]; regulation of protein phosphorylation [GO:0001932] GO:0000122; GO:0001932; GO:0005737; GO:0005765; GO:0005829; GO:0006468; GO:0008630; GO:0031334; GO:0033138; GO:0034451; GO:0042030; GO:0051087 15011 XM_029350306.2 1453 1183 863 1089 1100 Q9P278 9.64e-29 Folliculin-interacting protein 2 (FNIP1-like protein) (O6-methylguanine-induced apoptosis 1 protein) Homo sapiens (Human) intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein-containing complex assembly [GO:0031334]; protein phosphorylation [GO:0006468]; regulation of protein phosphorylation [GO:0001932] GO:0000122; GO:0001932; GO:0005737; GO:0005765; GO:0005829; GO:0006468; GO:0008630; GO:0031334; GO:0033138; GO:0034451; GO:0042030; GO:0051087 15012 XM_044325325.1 20 0 0 0 10 NA NA NA NA NA NA 15013 XM_044310150.1 164 79 167 174 254 NA NA NA NA NA NA 15014 XM_044311651.1 411 211 95 337 266 P05132 0 cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11) Mus musculus (Mouse) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cellular response to cold [GO:0070417]; cellular response to glucose stimulus [GO:0071333]; cellular response to heat [GO:0034605]; cellular response to parathyroid hormone stimulus [GO:0071374]; mesoderm formation [GO:0001707]; modulation of chemical synaptic transmission [GO:0050804]; mRNA processing [GO:0006397]; negative regulation of meiotic cell cycle [GO:0051447]; negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:1901621]; neural tube closure [GO:0001843]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of insulin secretion [GO:0032024]; positive regulation of protein export from nucleus [GO:0046827]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; protein autophosphorylation [GO:0046777]; protein export from nucleus [GO:0006611]; protein kinase A signaling [GO:0010737]; protein localization to lipid droplet [GO:1990044]; protein phosphorylation [GO:0006468]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of cell cycle [GO:0051726]; regulation of cellular respiration [GO:0043457]; regulation of osteoblast differentiation [GO:0045667]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of protein processing [GO:0070613]; regulation of synaptic transmission, glutamatergic [GO:0051966]; sperm capacitation [GO:0048240]; spontaneous exocytosis of neurotransmitter [GO:0048792] GO:0000287; GO:0001669; GO:0001707; GO:0001843; GO:0004672; GO:0004674; GO:0004679; GO:0004691; GO:0004712; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005794; GO:0005813; GO:0005829; GO:0005886; GO:0005930; GO:0005952; GO:0006397; GO:0006468; GO:0006611; GO:0007189; GO:0008284; GO:0010737; GO:0016020; GO:0016607; GO:0018105; GO:0018107; GO:0019901; GO:0019904; GO:0030145; GO:0031267; GO:0031588; GO:0031594; GO:0031625; GO:0032024; GO:0032991; GO:0034237; GO:0034605; GO:0036126; GO:0043005; GO:0043197; GO:0043457; GO:0044853; GO:0044877; GO:0045667; GO:0046777; GO:0046827; GO:0048240; GO:0048471; GO:0048792; GO:0050804; GO:0051447; GO:0051726; GO:0051966; GO:0061136; GO:0070417; GO:0070613; GO:0071333; GO:0071374; GO:0097225; GO:0097546; GO:0098793; GO:0098794; GO:0098978; GO:0099170; GO:0106310; GO:1901621; GO:1990044; GO:2000810 15015 XR_006393631.1 78 16 46 115 68 NA NA NA NA NA NA 15016 XM_029338747.2 9 2 20 9 24 E7FAM5 8.12e-76 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 15017 XM_044309178.1 57 12 9 61 42 NA NA NA NA NA NA 15018 XM_044323635.1 33 0 0 1 0 NA NA NA NA NA NA 15019 XM_044310751.1 17 0 14 5 121 NA NA NA NA NA NA 15020 XM_044310575.1 0 0 0 1 57 NA NA NA NA NA NA 15021 XM_044322698.1 801 538 448 1071 975 A0A0G2JEB6 0 Cilia and flagella-associated protein 47 Mus musculus (Mouse) sperm axoneme assembly [GO:0007288] GO:0005737; GO:0005856; GO:0007288; GO:0097224 15022 XM_029342582.2 142 38 49 97 187 NA NA NA NA NA NA 15023 XM_029333864.2 71 120 13 168 40 Q6P1R4 9.22e-164 tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like (EC 1.3.1.88) (tRNA-dihydrouridine synthase 1-like) Homo sapiens (Human) tRNA dihydrouridine synthesis [GO:0002943] GO:0002943; GO:0017150; GO:0050660 15024 XM_044319604.1 0 0 0 2 20 Q09575 6.33e-44 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 15025 XM_044324384.1 0 0 0 22 44 NA NA NA NA NA NA 15026 XM_029343821.2 65 71 64 41 0 NA NA NA NA NA NA 15027 XM_044323338.1 97 105 100 132 153 Q9H9B1 5.03e-149 Histone-lysine N-methyltransferase EHMT1 (EC 2.1.1.-) (EC 2.1.1.367) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a-like protein 1) (GLP) (GLP1) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Lysine N-methyltransferase 1D) Homo sapiens (Human) chromatin organization [GO:0006325]; DNA methylation [GO:0006306]; facultative heterochromatin formation [GO:0140718]; histone H3-K9 methylation [GO:0051567]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-lysine dimethylation [GO:0018027]; peptidyl-lysine monomethylation [GO:0018026]; positive regulation of cold-induced thermogenesis [GO:0120162]; regulation of embryonic development [GO:0045995]; regulation of histone H3-K9 methylation [GO:0051570] GO:0000122; GO:0000785; GO:0001222; GO:0002039; GO:0005634; GO:0005654; GO:0006306; GO:0006325; GO:0008168; GO:0008270; GO:0016279; GO:0016604; GO:0018024; GO:0018026; GO:0018027; GO:0045892; GO:0045995; GO:0046974; GO:0046976; GO:0051567; GO:0051570; GO:0070742; GO:0120162; GO:0140718; GO:0140947 15028 XM_029346514.2 0 0 0 205 97 Q9PTS8 2.57e-93 Neuronal acetylcholine receptor subunit alpha-9 (Nicotinic acetylcholine receptor subunit alpha-9) (NACHR alpha-9) Gallus gallus (Chicken) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; regulation of nitric oxide metabolic process [GO:0080164]; response to auditory stimulus [GO:0010996]; signal transduction [GO:0007165] GO:0004888; GO:0005231; GO:0005262; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0010996; GO:0022848; GO:0030594; GO:0034220; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051899; GO:0080164; GO:1904315 15029 XM_029331343.2 29 5 0 78 46 P52569 2.07e-123 Cationic amino acid transporter 2 (CAT-2) (CAT2) (Low affinity cationic amino acid transporter 2) (Solute carrier family 7 member 2) Homo sapiens (Human) amino acid import across plasma membrane [GO:0089718]; amino acid transport [GO:0006865]; L-alpha-amino acid transmembrane transport [GO:1902475]; L-amino acid transport [GO:0015807]; L-arginine import across plasma membrane [GO:0097638]; L-arginine transmembrane transport [GO:1903826]; L-ornithine transmembrane transport [GO:1903352]; transport across blood-brain barrier [GO:0150104] GO:0000064; GO:0005886; GO:0006865; GO:0015171; GO:0015174; GO:0015179; GO:0015189; GO:0015807; GO:0030054; GO:0061459; GO:0089718; GO:0097638; GO:0150104; GO:1902475; GO:1903352; GO:1903826 15030 XM_029355444.2 5 9 7 3 5 NA NA NA NA NA NA 15031 XM_044306838.1 0 0 2 41 0 NA NA NA NA NA NA 15032 XM_044324575.1 43 355 86 658 189 NA NA NA NA NA NA 15033 XM_044314393.1 12 0 5 0 0 NA NA NA NA NA NA 15034 XR_006396191.1 34 0 0 89 43 Q9XTG7 1.1e-22 Serine/threonine-protein kinase akt-2 (EC 2.7.11.1) (Protein kinase B akt-2) (PKB akt-2) Caenorhabditis elegans determination of adult lifespan [GO:0008340]; innate immune response [GO:0045087]; insulin receptor signaling pathway [GO:0008286]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; protein phosphorylation [GO:0006468]; regulation of gene expression [GO:0010468]; regulation of synaptic assembly at neuromuscular junction [GO:0008582] GO:0004672; GO:0004674; GO:0005524; GO:0005547; GO:0006468; GO:0008286; GO:0008340; GO:0008582; GO:0010468; GO:0018105; GO:0018107; GO:0035556; GO:0045087; GO:0046872; GO:0106310; GO:1902911 15035 XM_029356504.2 17 43 9 5 15 NA NA NA NA NA NA 15036 XM_044321763.1 808 642 0 492 8 O57656 1.05e-111 Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic (GPD-C) (GPDH-C) (EC 1.1.1.8) Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate catabolic process [GO:0046168] GO:0005975; GO:0009331; GO:0042803; GO:0046168; GO:0047952; GO:0051287 15037 XM_044309931.1 1 7 1 4 9 NA NA NA NA NA NA 15038 XM_029324812.2 83 116 96 28 32 Q6P606 1.67e-27 LysM and putative peptidoglycan-binding domain-containing protein 4 Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0016020 15039 XM_044307570.1 0 141 0 55 23 P22027 7.68e-31 ATP synthase subunit s, mitochondrial (ATP synthase-coupling factor B) (FB) (Distal membrane arm assembly complex 2-like protein) (Mitochondrial ATP synthase regulatory component factor B) Bos taurus (Bovine) ATP biosynthetic process [GO:0006754]; proton transmembrane transport [GO:1902600] GO:0005737; GO:0005743; GO:0006754; GO:0045263; GO:0046872; GO:1902600 15040 XM_029354476.2 205 33 111 122 216 Q6AX80 3.61e-83 Bis(5'-adenosyl)-triphosphatase enpp4 (EC 3.6.1.29) (AP3A hydrolase) (AP3Aase) (Ectonucleotide pyrophosphatase/phosphodiesterase family member 4) (E-NPP 4) (NPP-4) Xenopus laevis (African clawed frog) blood coagulation [GO:0007596] GO:0005886; GO:0007596; GO:0046872; GO:0047710 15041 XM_044314825.1 10 287 585 248 0 NA NA NA NA NA NA 15042 XM_044313025.1 9 25 21 0 0 Q2KIP6 8.56e-23 Kappa-type opioid receptor (K-OR-1) (KOR-1) Bos taurus (Bovine) adenylate cyclase-inhibiting opioid receptor signaling pathway [GO:0031635]; defense response to virus [GO:0051607]; G protein-coupled opioid receptor signaling pathway [GO:0038003]; immune response [GO:0006955]; locomotory behavior [GO:0007626]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; regulation of saliva secretion [GO:0046877]; sensory perception of pain [GO:0019233] GO:0004930; GO:0004985; GO:0005654; GO:0005829; GO:0005886; GO:0006955; GO:0007200; GO:0007218; GO:0007626; GO:0016020; GO:0019233; GO:0031635; GO:0038003; GO:0038048; GO:0042277; GO:0042923; GO:0043005; GO:0046877; GO:0051607 15043 XR_006392876.1 41 2 25 5 151 NA NA NA NA NA NA 15044 XR_006392209.1 13 0 0 4 0 NA NA NA NA NA NA 15045 XM_029343629.2 2358 1455 2264 3866 3379 Q91Z40 2.51e-46 Guanylate-binding protein 7 (EC 3.6.5.-) (GTP-binding protein 7) (GBP-7) (Guanine nucleotide-binding protein 7) (Guanylate-binding protein 4-like) Mus musculus (Mouse) adhesion of symbiont to host [GO:0044406]; cellular response to interferon-beta [GO:0035458]; cellular response to type II interferon [GO:0071346]; defense response to Gram-positive bacterium [GO:0050830]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; negative regulation of cytokine production [GO:0001818]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of type I interferon production [GO:0032480]; negative regulation of type III interferon production [GO:0034345]; positive regulation of viral genome replication [GO:0045070]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122] GO:0001818; GO:0003924; GO:0005525; GO:0016020; GO:0020005; GO:0031410; GO:0032480; GO:0034345; GO:0035458; GO:0042832; GO:0043122; GO:0044406; GO:0045070; GO:0046426; GO:0050830; GO:0051607; GO:0071346 15046 XM_044318504.1 150 195 114 3 152 B2RYF1 3.42e-141 Protein phosphatase 1 regulatory subunit 37 (Leucine-rich repeat-containing protein 68) Rattus norvegicus (Rat) NA GO:0004864 15047 XM_029330084.2 0 0 47 48 160 Q14155 3.71e-155 Rho guanine nucleotide exchange factor 7 (Beta-Pix) (COOL-1) (PAK-interacting exchange factor beta) (p85) Homo sapiens (Human) ephrin receptor signaling pathway [GO:0048013]; focal adhesion assembly [GO:0048041]; Golgi organization [GO:0007030]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; negative regulation of microtubule nucleation [GO:1905833]; nervous system development [GO:0007399]; positive regulation of apoptotic process [GO:0043065]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of GTPase activity [GO:0043547]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of GTP binding [GO:1904424]; signal transduction [GO:0007165] GO:0001726; GO:0005085; GO:0005737; GO:0005813; GO:0005829; GO:0005925; GO:0005938; GO:0007030; GO:0007165; GO:0007399; GO:0010763; GO:0019901; GO:0030027; GO:0030032; GO:0032991; GO:0035556; GO:0043005; GO:0043015; GO:0043025; GO:0043065; GO:0043547; GO:0048013; GO:0048041; GO:0097431; GO:0098794; GO:1900026; GO:1904424; GO:1905833; GO:2000394 15048 XM_044316943.1 9 0 2 1 73 NA NA NA NA NA NA 15049 XR_003826916.2 0 0 38 39 48 Q9CPV7 1.05e-91 Palmitoyltransferase ZDHHC6 (EC 2.3.1.225) (Stearoyltransferase ZDHHC6) (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 6) (DHHC-6) Mus musculus (Mouse) peptidyl-L-cysteine S-palmitoylation [GO:0018230]; positive regulation of mitochondrial fusion [GO:0010636]; protein palmitoylation [GO:0018345]; protein stearoylation [GO:0140438]; protein targeting to membrane [GO:0006612] GO:0005783; GO:0005789; GO:0005794; GO:0006612; GO:0010636; GO:0016409; GO:0018230; GO:0018345; GO:0019706; GO:0140438; GO:0140439 15050 XR_006394177.1 10 0 10 0 33 NA NA NA NA NA NA 15051 XM_029346823.2 1565 1233 1135 1844 1671 Q9I7T7 2.09e-68 La-related protein Larp4B (La ribonucleoprotein domain family member Larp4B) Drosophila melanogaster (Fruit fly) negative regulation of cell growth [GO:0030308]; negative regulation of translation [GO:0017148]; positive regulation of translation [GO:0045727] GO:0003723; GO:0003730; GO:0005829; GO:0010494; GO:0017148; GO:0030308; GO:0045727 15052 XR_006397400.1 52 11 80 77 111 NA NA NA NA NA NA 15053 XM_044311103.1 0 0 0 0 19 NA NA NA NA NA NA 15054 XM_029338266.2 93 7 28 105 41 Q9EPX2 1.07e-53 Papilin Mus musculus (Mouse) extracellular matrix organization [GO:0030198]; negative regulation of peptidase activity [GO:0010466] GO:0004222; GO:0004867; GO:0005576; GO:0005604; GO:0010466; GO:0030198; GO:0031012; GO:0062023 15055 XM_029329073.2 53 69 22 61 23 P41240 5.16e-134 Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase CYL) Homo sapiens (Human) adaptive immune response [GO:0002250]; adherens junction organization [GO:0034332]; brain development [GO:0007420]; cellular response to peptide hormone stimulus [GO:0071375]; negative regulation of bone resorption [GO:0045779]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of Golgi to plasma membrane protein transport [GO:0042997]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of kinase activity [GO:0033673]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of phagocytosis [GO:0050765]; oligodendrocyte differentiation [GO:0048709]; positive regulation of MAP kinase activity [GO:0043406]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of Fc receptor mediated stimulatory signaling pathway [GO:0060368]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852] GO:0002250; GO:0004713; GO:0004715; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0005911; GO:0006468; GO:0007420; GO:0008022; GO:0008285; GO:0010989; GO:0019903; GO:0031295; GO:0032715; GO:0033673; GO:0034236; GO:0034332; GO:0042802; GO:0042997; GO:0043406; GO:0045121; GO:0045779; GO:0046777; GO:0046872; GO:0048709; GO:0050765; GO:0050852; GO:0060368; GO:0070062; GO:0070064; GO:0070373; GO:0071375; GO:1990782 15056 XM_029329073.2 53 69 22 61 23 P41240 5.16e-134 Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase CYL) Homo sapiens (Human) adaptive immune response [GO:0002250]; adherens junction organization [GO:0034332]; brain development [GO:0007420]; cellular response to peptide hormone stimulus [GO:0071375]; negative regulation of bone resorption [GO:0045779]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of Golgi to plasma membrane protein transport [GO:0042997]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of kinase activity [GO:0033673]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of phagocytosis [GO:0050765]; oligodendrocyte differentiation [GO:0048709]; positive regulation of MAP kinase activity [GO:0043406]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of Fc receptor mediated stimulatory signaling pathway [GO:0060368]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852] GO:0002250; GO:0004713; GO:0004715; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0005911; GO:0006468; GO:0007420; GO:0008022; GO:0008285; GO:0010989; GO:0019903; GO:0031295; GO:0032715; GO:0033673; GO:0034236; GO:0034332; GO:0042802; GO:0042997; GO:0043406; GO:0045121; GO:0045779; GO:0046777; GO:0046872; GO:0048709; GO:0050765; GO:0050852; GO:0060368; GO:0070062; GO:0070064; GO:0070373; GO:0071375; GO:1990782 15057 XM_044321640.1 104 97 294 14 53 P49914 9.37e-69 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) (5,10-methenyl-tetrahydrofolate synthetase) (MTHFS) (Methenyl-THF synthetase) Homo sapiens (Human) folic acid catabolic process [GO:0046657]; folic acid metabolic process [GO:0046655]; folic acid-containing compound biosynthetic process [GO:0009396]; formate metabolic process [GO:0015942]; glutamate metabolic process [GO:0006536]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653] GO:0005524; GO:0005542; GO:0005737; GO:0005739; GO:0005759; GO:0005829; GO:0006536; GO:0009396; GO:0015942; GO:0030272; GO:0035999; GO:0046653; GO:0046655; GO:0046657; GO:0046872 15058 XM_029342142.2 614 380 360 952 722 O97827 1.55e-46 Adhesion G protein-coupled receptor L3 (Latrophilin-3) Bos taurus (Bovine) cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; neuron migration [GO:0001764]; signal transduction [GO:0007165]; synapse assembly [GO:0007416] GO:0001764; GO:0004930; GO:0005509; GO:0005615; GO:0005886; GO:0005911; GO:0007165; GO:0007166; GO:0007416; GO:0030246; GO:0030424; GO:0098742 15059 XM_044328605.1 38 72 41 12 92 P08478 1.92e-114 Peptidyl-glycine alpha-amidating monooxygenase A (PAM-A) (Peptide C-terminal alpha-amidating enzyme I) (AE-I) (Peptidyl-glycine alpha-amidating monooxygenase I) [Includes: Peptidylglycine alpha-hydroxylating monooxygenase A (PHM-A) (EC 1.14.17.3); Peptidyl-alpha-hydroxyglycine alpha-amidating lyase A (EC 4.3.2.5) (Peptidylamidoglycolate lyase-A) (PAL-A)] Xenopus laevis (African clawed frog) peptide metabolic process [GO:0006518] GO:0004504; GO:0004598; GO:0005507; GO:0006518; GO:0030658 15060 XM_044313238.1 23 0 1 0 0 NA NA NA NA NA NA 15061 XM_044323278.1 0 6 4 37 0 NA NA NA NA NA NA 15062 XM_029328753.2 1096 834 553 994 1107 Q8IZ69 1.59e-144 tRNA (uracil-5-)-methyltransferase homolog A (EC 2.1.1.35) (mRNA (uracil-5-)-methyltransferase TRMT2A) (EC 2.1.1.-) Homo sapiens (Human) mRNA processing [GO:0006397] GO:0003723; GO:0005829; GO:0006397; GO:0008169; GO:0030697 15063 XM_029340048.2 166 0 54 41 160 F1QB81 1.36e-21 NA NA NA NA 15064 XM_029345521.2 128 39 31 57 92 Q9SE95 1.59e-26 FH protein interacting protein FIP2 (BTB/POZ domain-containing protein At5g55000) Arabidopsis thaliana (Mouse-ear cress) protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567] GO:0016567; GO:0051260 15065 XR_006393802.1 0 8 0 0 2 NA NA NA NA NA NA 15066 XM_044314086.1 98 121 67 121 276 NA NA NA NA NA NA 15067 XM_029334503.2 85 35 26 60 52 Q6DKN2 3.05e-28 Homeobox protein OTX2-B (xOTX2-B) (Orthodenticle 2-B) (Orthodenticle-A-like protein B) Xenopus laevis (African clawed frog) NA GO:0000981; GO:0003677; GO:0005634 15068 XM_044318167.1 754 720 538 716 753 NA NA NA NA NA NA 15069 XM_029328967.2 300 225 119 131 174 P24044 2.52e-21 Calmodulin Plasmodium falciparum NA GO:0005509; GO:0005737; GO:0020007 15070 XM_044308223.1 651 474 453 753 1018 NA NA NA NA NA NA 15071 XM_029344661.2 2885 5115 3529 2532 1641 Q29036 1.26e-52 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 (Oligosaccharyl transferase subunit DAD1) (Defender against cell death 1) (DAD-1) Sus scrofa (Pig) apoptotic process [GO:0006915]; blastocyst development [GO:0001824]; negative regulation of apoptotic process [GO:0043066]; protein glycosylation [GO:0006486]; protein N-linked glycosylation [GO:0006487]; regulation of protein stability [GO:0031647] GO:0001824; GO:0006486; GO:0006487; GO:0006915; GO:0008047; GO:0008250; GO:0031647; GO:0043066 15072 XM_029328065.2 0 0 0 0 25 NA NA NA NA NA NA 15073 XM_029326581.2 2 9 13 19 35 P0CT39 3.84e-41 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 15074 XM_029326581.2 2 9 13 19 35 P0CT39 3.84e-41 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 15075 XM_044317483.1 0 0 0 341 0 Q13114 2.64e-99 TNF receptor-associated factor 3 (EC 2.3.2.27) (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein 1) (LAP1) (RING-type E3 ubiquitin transferase TRAF3) Homo sapiens (Human) apoptotic process [GO:0006915]; defense response to virus [GO:0051607]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of JNK cascade [GO:0046330]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of cytokine production [GO:0001817]; regulation of defense response to virus [GO:0050688]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of interferon-beta production [GO:0032648]; regulation of proteolysis [GO:0030162]; signal transduction [GO:0007165]; Toll signaling pathway [GO:0008063]; toll-like receptor signaling pathway [GO:0002224]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; type I interferon-mediated signaling pathway [GO:0060337] GO:0000151; GO:0001817; GO:0002224; GO:0004842; GO:0005164; GO:0005739; GO:0005768; GO:0005829; GO:0006915; GO:0007165; GO:0008063; GO:0008270; GO:0009898; GO:0019901; GO:0019903; GO:0030162; GO:0031625; GO:0031996; GO:0032088; GO:0032648; GO:0033209; GO:0035631; GO:0035666; GO:0042802; GO:0042981; GO:0043122; GO:0046330; GO:0050688; GO:0051607; GO:0060337; GO:0070534; GO:1902554 15076 XM_044328844.1 0 0 0 39 0 Q9CL21 9.55e-25 ATP-dependent DNA helicase RecQ (EC 3.6.4.12) Pasteurella multocida (strain Pm70) DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; SOS response [GO:0009432] GO:0003677; GO:0005524; GO:0006260; GO:0006281; GO:0006310; GO:0009432; GO:0016887; GO:0043138 15077 XM_044309887.1 47 112 12 120 98 NA NA NA NA NA NA 15078 XM_029327743.2 3 12 2 5 15 NA NA NA NA NA NA 15079 XM_044320335.1 15 1 7 23 10 Q90268 2.89e-61 Paired box protein Pax-2a (No isthmus protein) (Pax[Zf-b]) Danio rerio (Zebrafish) (Brachydanio rerio) anatomical structure development [GO:0048856]; anterior/posterior pattern specification [GO:0009952]; anterior/posterior pattern specification involved in pronephros development [GO:0034672]; cell fate specification [GO:0001708]; cerebellum development [GO:0021549]; cerebellum formation [GO:0021588]; cilium assembly [GO:0060271]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic pattern specification [GO:0009880]; hindbrain development [GO:0030902]; inner ear receptor cell differentiation [GO:0060113]; kidney development [GO:0001822]; locus ceruleus development [GO:0021703]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; nervous system development [GO:0007399]; otic placode formation [GO:0043049]; peripheral nervous system development [GO:0007422]; pronephric glomerulus morphogenesis [GO:0035775]; pronephros development [GO:0048793]; pronephros morphogenesis [GO:0072114]; regulation of transcription by RNA polymerase II [GO:0006357]; thyroid gland development [GO:0030878]; vestibular receptor cell development [GO:0060118] GO:0000978; GO:0000981; GO:0001708; GO:0001822; GO:0003677; GO:0003700; GO:0005634; GO:0006357; GO:0007399; GO:0007422; GO:0009880; GO:0009952; GO:0021549; GO:0021588; GO:0021703; GO:0030878; GO:0030901; GO:0030902; GO:0030917; GO:0034672; GO:0035775; GO:0043049; GO:0043565; GO:0048596; GO:0048793; GO:0048856; GO:0060113; GO:0060118; GO:0060271; GO:0072114 15080 XM_044307617.1 18 109 41 68 351 NA NA NA NA NA NA 15081 XM_029356233.2 1071 801 880 813 1591 NA NA NA NA NA NA 15082 XM_029345012.2 168 136 96 174 184 P70627 8.55e-161 Glutamate carboxypeptidase 2 (EC 3.4.17.21) (Folate hydrolase 1) (Folylpoly-gamma-glutamate carboxypeptidase) (FGCP) (Glutamate carboxypeptidase II) (GCPII) (Membrane glutamate carboxypeptidase) (mGCP) (N-acetylated-alpha-linked acidic dipeptidase I) (NAALADase I) (Prostate-specific membrane antigen homolog) (Pteroylpoly-gamma-glutamate carboxypeptidase) Rattus norvegicus (Rat) C-terminal protein deglutamylation [GO:0035609]; folic acid-containing compound metabolic process [GO:0006760]; positive regulation of apoptotic process [GO:0043065]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508] GO:0004180; GO:0004181; GO:0005886; GO:0006508; GO:0006760; GO:0008233; GO:0009986; GO:0016020; GO:0016805; GO:0030163; GO:0035609; GO:0043065; GO:0046872; GO:1904492; GO:1904493 15083 XM_044310229.1 0 0 6 0 0 NA NA NA NA NA NA 15084 XM_029346013.2 0 277 0 294 452 Q9VBW3 4.63e-82 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 15085 XM_029355876.2 808 657 428 807 510 Q5E951 3.33e-74 Tubulin-folding cofactor B (Cytoskeleton-associated protein 1) (Cytoskeleton-associated protein CKAPI) (Tubulin-specific chaperone B) Bos taurus (Bovine) cell differentiation [GO:0030154]; nervous system development [GO:0007399] GO:0005737; GO:0005829; GO:0005874; GO:0007399; GO:0030154 15086 XM_044319878.1 0 116 49 16 66 Q9QZ85 1.75e-50 Interferon-inducible GTPase 1 (EC 3.6.5.-) Mus musculus (Mouse) cellular response to interferon-beta [GO:0035458]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; regulation of autophagy [GO:0010506]; response to bacterium [GO:0009617] GO:0003924; GO:0005525; GO:0005737; GO:0005789; GO:0006952; GO:0009617; GO:0010506; GO:0019003; GO:0019221; GO:0020005; GO:0031965; GO:0032580; GO:0035458; GO:0042802; GO:0042832; GO:0045087; GO:0050829 15087 XM_044324196.1 151 0 0 0 8 Q14409 0 Glycerol kinase 3 (GK 3) (Glycerokinase 3) (EC 2.7.1.30) (ATP:glycerol 3-phosphotransferase 3) (Glycerol kinase 3 pseudogene) (Glycerol kinase, testis specific 1) Homo sapiens (Human) glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate biosynthetic process [GO:0046167]; phosphorylation [GO:0016310]; triglyceride metabolic process [GO:0006641] GO:0004370; GO:0005524; GO:0005739; GO:0005741; GO:0006071; GO:0006641; GO:0016310; GO:0016773; GO:0019563; GO:0046167 15088 XM_029339410.2 917 482 647 1410 1440 P21359 0 Neurofibromin (Neurofibromatosis-related protein NF-1) [Cleaved into: Neurofibromin truncated] Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; adrenal gland development [GO:0030325]; amygdala development [GO:0021764]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; brain development [GO:0007420]; camera-type eye morphogenesis [GO:0048593]; cell communication [GO:0007154]; cellular response to heat [GO:0034605]; cerebral cortex development [GO:0021987]; cognition [GO:0050890]; collagen fibril organization [GO:0030199]; endothelial cell proliferation [GO:0001935]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; fibroblast proliferation [GO:0048144]; forebrain astrocyte development [GO:0021897]; forebrain morphogenesis [GO:0048853]; gamma-aminobutyric acid secretion, neurotransmission [GO:0061534]; glutamate secretion, neurotransmission [GO:0061535]; hair follicle maturation [GO:0048820]; heart development [GO:0007507]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; mast cell apoptotic process [GO:0033024]; mast cell proliferation [GO:0070662]; metanephros development [GO:0001656]; myelination in peripheral nervous system [GO:0022011]; myeloid leukocyte migration [GO:0097529]; negative regulation of angiogenesis [GO:0016525]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of mast cell proliferation [GO:0070667]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of neurotransmitter secretion [GO:0046929]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of protein import into nucleus [GO:0042308]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of Rac protein signal transduction [GO:0035021]; negative regulation of Schwann cell migration [GO:1900148]; negative regulation of Schwann cell proliferation [GO:0010626]; negative regulation of stem cell proliferation [GO:2000647]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; neural tube development [GO:0021915]; neuroblast proliferation [GO:0007405]; neuron apoptotic process [GO:0051402]; observational learning [GO:0098597]; oligodendrocyte differentiation [GO:0048709]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; pigmentation [GO:0043473]; positive regulation of adenylate cyclase activity [GO:0045762]; positive regulation of apoptotic process [GO:0043065]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of GTPase activity [GO:0043547]; positive regulation of mast cell apoptotic process [GO:0033027]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of vascular associated smooth muscle cell proliferation [GO:1904707]; protein import into nucleus [GO:0006606]; Rac protein signal transduction [GO:0016601]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of bone resorption [GO:0045124]; regulation of cell-matrix adhesion [GO:0001952]; regulation of gene expression [GO:0010468]; regulation of glial cell differentiation [GO:0045685]; regulation of GTPase activity [GO:0043087]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of long-term synaptic potentiation [GO:1900271]; regulation of postsynapse organization [GO:0099175]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to hypoxia [GO:0001666]; Schwann cell development [GO:0014044]; Schwann cell migration [GO:0036135]; Schwann cell proliferation [GO:0014010]; skeletal muscle tissue development [GO:0007519]; smooth muscle tissue development [GO:0048745]; spinal cord development [GO:0021510]; stem cell proliferation [GO:0072089]; sympathetic nervous system development [GO:0048485]; vascular associated smooth muscle cell migration [GO:1904738]; vascular associated smooth muscle cell proliferation [GO:1990874]; visual learning [GO:0008542]; wound healing [GO:0042060] GO:0000165; GO:0001525; GO:0001649; GO:0001656; GO:0001666; GO:0001889; GO:0001935; GO:0001937; GO:0001938; GO:0001952; GO:0001953; GO:0002686; GO:0005096; GO:0005634; GO:0005730; GO:0005737; GO:0005829; GO:0005886; GO:0006469; GO:0006606; GO:0007154; GO:0007265; GO:0007405; GO:0007406; GO:0007420; GO:0007422; GO:0007507; GO:0007519; GO:0008429; GO:0008542; GO:0008625; GO:0010468; GO:0010626; GO:0014010; GO:0014044; GO:0014065; GO:0016020; GO:0016525; GO:0016601; GO:0021510; GO:0021764; GO:0021897; GO:0021915; GO:0021987; GO:0022011; GO:0030036; GO:0030198; GO:0030199; GO:0030316; GO:0030325; GO:0030336; GO:0030424; GO:0030425; GO:0031210; GO:0032228; GO:0033024; GO:0033027; GO:0034605; GO:0035021; GO:0036135; GO:0042060; GO:0042308; GO:0043065; GO:0043087; GO:0043407; GO:0043409; GO:0043473; GO:0043525; GO:0043535; GO:0043547; GO:0045124; GO:0045671; GO:0045685; GO:0045762; GO:0045765; GO:0046929; GO:0048144; GO:0048147; GO:0048169; GO:0048485; GO:0048593; GO:0048709; GO:0048712; GO:0048715; GO:0048745; GO:0048820; GO:0048844; GO:0048853; GO:0050890; GO:0051402; GO:0061534; GO:0061535; GO:0070662; GO:0070667; GO:0072089; GO:0097192; GO:0097529; GO:0098597; GO:0098793; GO:0098978; GO:0099175; GO:1900148; GO:1900271; GO:1904707; GO:1904738; GO:1904753; GO:1990874; GO:2000647; GO:2001241 15089 XM_029353937.2 0 34 16 181 160 D4A9K4 4.44e-54 MFS-type transporter SLC18B1 (Solute carrier family 18 member B1) (Vesicular polyamine transporter) (VPAT) Rattus norvegicus (Rat) serotonin transport [GO:0006837]; serotonin uptake [GO:0051610]; spermidine transport [GO:0015848]; spermine transport [GO:0000296] GO:0000296; GO:0006837; GO:0015311; GO:0015312; GO:0015848; GO:0022857; GO:0030667; GO:0030672; GO:0051610 15090 XM_044323396.1 133 60 201 55 427 Q5U5D4 0 GATOR complex protein MIOS-A Xenopus laevis (African clawed frog) NA GO:0005765 15091 XM_044316808.1 0 0 1 16 0 NA NA NA NA NA NA 15092 XM_029333307.2 0 0 57 0 28 A0A1D5NSM8 1.42e-36 NA NA NA NA 15093 XM_029348437.2 585 505 231 344 443 NA NA NA NA NA NA 15094 XM_044313615.1 129 39 65 28 31 Q6DG03 5.31e-50 Cyclin-D-binding Myb-like transcription factor 1 Danio rerio (Zebrafish) (Brachydanio rerio) cell cycle [GO:0007049]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000976; GO:0000978; GO:0000981; GO:0003700; GO:0005634; GO:0006355; GO:0006357; GO:0007049 15095 XM_029329677.2 811 615 641 803 817 Q8VEL2 1.02e-154 Myotubularin-related protein 14 (EC 3.1.3.-) (mJumpy) Mus musculus (Mouse) dephosphorylation [GO:0016311] GO:0001726; GO:0004438; GO:0016311; GO:0048471 15096 XM_029339435.2 290 98 117 269 160 P19801 4.66e-142 Amiloride-sensitive amine oxidase [copper-containing] (DAO) (Diamine oxidase) (EC 1.4.3.22) (Amiloride-binding protein 1) (Amine oxidase copper domain-containing protein 1) (Histaminase) (Kidney amine oxidase) (KAO) Homo sapiens (Human) amine metabolic process [GO:0009308]; cellular response to azide [GO:0097185]; cellular response to copper ion [GO:0071280]; cellular response to copper ion starvation [GO:0035874]; cellular response to heparin [GO:0071504]; cellular response to histamine [GO:0071420]; putrescine metabolic process [GO:0009445]; response to antibiotic [GO:0046677] GO:0005507; GO:0005509; GO:0005576; GO:0005615; GO:0005777; GO:0005886; GO:0005923; GO:0008131; GO:0008201; GO:0008270; GO:0009308; GO:0009445; GO:0035580; GO:0035874; GO:0042803; GO:0044877; GO:0046677; GO:0048038; GO:0052597; GO:0052598; GO:0052599; GO:0052600; GO:0070062; GO:0071280; GO:0071420; GO:0071504; GO:0097185 15097 XM_044325282.1 3097 3150 22 3406 763 Q01484 0 Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin) Homo sapiens (Human) atrial cardiac muscle cell action potential [GO:0086014]; atrial cardiac muscle cell to AV node cell communication [GO:0086066]; atrial septum development [GO:0003283]; cellular calcium ion homeostasis [GO:0006874]; endocytosis [GO:0006897]; membrane depolarization during SA node cell action potential [GO:0086046]; paranodal junction assembly [GO:0030913]; positive regulation of calcium ion transmembrane transporter activity [GO:1901021]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cation channel activity [GO:2001259]; positive regulation of gene expression [GO:0010628]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to endoplasmic reticulum [GO:0070972]; protein localization to M-band [GO:0036309]; protein localization to organelle [GO:0033365]; protein localization to plasma membrane [GO:0072659]; protein localization to T-tubule [GO:0036371]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; regulation of atrial cardiac muscle cell action potential [GO:0098910]; regulation of calcium ion transmembrane transporter activity [GO:1901019]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of heart rate [GO:0002027]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of protein stability [GO:0031647]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of SA node cell action potential [GO:0098907]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; response to methylmercury [GO:0051597]; SA node cell action potential [GO:0086015]; SA node cell to atrial cardiac muscle cell communication [GO:0086070]; sarcoplasmic reticulum calcium ion transport [GO:0070296]; T-tubule organization [GO:0033292]; ventricular cardiac muscle cell action potential [GO:0086005] GO:0002027; GO:0003283; GO:0005200; GO:0005739; GO:0005764; GO:0005769; GO:0005829; GO:0005856; GO:0005886; GO:0006874; GO:0006897; GO:0008093; GO:0008104; GO:0010628; GO:0010881; GO:0010882; GO:0014704; GO:0015031; GO:0016323; GO:0016324; GO:0019899; GO:0019901; GO:0030018; GO:0030315; GO:0030507; GO:0030674; GO:0030913; GO:0031430; GO:0031647; GO:0031672; GO:0033292; GO:0033365; GO:0034394; GO:0036309; GO:0036371; GO:0042383; GO:0043005; GO:0043034; GO:0043268; GO:0044325; GO:0045121; GO:0045211; GO:0050821; GO:0051117; GO:0051279; GO:0051597; GO:0051924; GO:0051928; GO:0055037; GO:0055117; GO:0060307; GO:0070296; GO:0070972; GO:0072659; GO:0086004; GO:0086005; GO:0086014; GO:0086015; GO:0086046; GO:0086066; GO:0086070; GO:0086091; GO:0098907; GO:0098910; GO:0140031; GO:1901018; GO:1901019; GO:1901021; GO:2001259 15098 XM_044325282.1 3097 3150 22 3406 763 Q01484 1.2e-105 Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin) Homo sapiens (Human) atrial cardiac muscle cell action potential [GO:0086014]; atrial cardiac muscle cell to AV node cell communication [GO:0086066]; atrial septum development [GO:0003283]; cellular calcium ion homeostasis [GO:0006874]; endocytosis [GO:0006897]; membrane depolarization during SA node cell action potential [GO:0086046]; paranodal junction assembly [GO:0030913]; positive regulation of calcium ion transmembrane transporter activity [GO:1901021]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cation channel activity [GO:2001259]; positive regulation of gene expression [GO:0010628]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to endoplasmic reticulum [GO:0070972]; protein localization to M-band [GO:0036309]; protein localization to organelle [GO:0033365]; protein localization to plasma membrane [GO:0072659]; protein localization to T-tubule [GO:0036371]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; regulation of atrial cardiac muscle cell action potential [GO:0098910]; regulation of calcium ion transmembrane transporter activity [GO:1901019]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of heart rate [GO:0002027]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of protein stability [GO:0031647]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of SA node cell action potential [GO:0098907]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; response to methylmercury [GO:0051597]; SA node cell action potential [GO:0086015]; SA node cell to atrial cardiac muscle cell communication [GO:0086070]; sarcoplasmic reticulum calcium ion transport [GO:0070296]; T-tubule organization [GO:0033292]; ventricular cardiac muscle cell action potential [GO:0086005] GO:0002027; GO:0003283; GO:0005200; GO:0005739; GO:0005764; GO:0005769; GO:0005829; GO:0005856; GO:0005886; GO:0006874; GO:0006897; GO:0008093; GO:0008104; GO:0010628; GO:0010881; GO:0010882; GO:0014704; GO:0015031; GO:0016323; GO:0016324; GO:0019899; GO:0019901; GO:0030018; GO:0030315; GO:0030507; GO:0030674; GO:0030913; GO:0031430; GO:0031647; GO:0031672; GO:0033292; GO:0033365; GO:0034394; GO:0036309; GO:0036371; GO:0042383; GO:0043005; GO:0043034; GO:0043268; GO:0044325; GO:0045121; GO:0045211; GO:0050821; GO:0051117; GO:0051279; GO:0051597; GO:0051924; GO:0051928; GO:0055037; GO:0055117; GO:0060307; GO:0070296; GO:0070972; GO:0072659; GO:0086004; GO:0086005; GO:0086014; GO:0086015; GO:0086046; GO:0086066; GO:0086070; GO:0086091; GO:0098907; GO:0098910; GO:0140031; GO:1901018; GO:1901019; GO:1901021; GO:2001259 15099 XM_044325282.1 3097 3150 22 3406 763 Q01484 1.32e-103 Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin) Homo sapiens (Human) atrial cardiac muscle cell action potential [GO:0086014]; atrial cardiac muscle cell to AV node cell communication [GO:0086066]; atrial septum development [GO:0003283]; cellular calcium ion homeostasis [GO:0006874]; endocytosis [GO:0006897]; membrane depolarization during SA node cell action potential [GO:0086046]; paranodal junction assembly [GO:0030913]; positive regulation of calcium ion transmembrane transporter activity [GO:1901021]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cation channel activity [GO:2001259]; positive regulation of gene expression [GO:0010628]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to endoplasmic reticulum [GO:0070972]; protein localization to M-band [GO:0036309]; protein localization to organelle [GO:0033365]; protein localization to plasma membrane [GO:0072659]; protein localization to T-tubule [GO:0036371]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; regulation of atrial cardiac muscle cell action potential [GO:0098910]; regulation of calcium ion transmembrane transporter activity [GO:1901019]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of heart rate [GO:0002027]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of protein stability [GO:0031647]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of SA node cell action potential [GO:0098907]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; response to methylmercury [GO:0051597]; SA node cell action potential [GO:0086015]; SA node cell to atrial cardiac muscle cell communication [GO:0086070]; sarcoplasmic reticulum calcium ion transport [GO:0070296]; T-tubule organization [GO:0033292]; ventricular cardiac muscle cell action potential [GO:0086005] GO:0002027; GO:0003283; GO:0005200; GO:0005739; GO:0005764; GO:0005769; GO:0005829; GO:0005856; GO:0005886; GO:0006874; GO:0006897; GO:0008093; GO:0008104; GO:0010628; GO:0010881; GO:0010882; GO:0014704; GO:0015031; GO:0016323; GO:0016324; GO:0019899; GO:0019901; GO:0030018; GO:0030315; GO:0030507; GO:0030674; GO:0030913; GO:0031430; GO:0031647; GO:0031672; GO:0033292; GO:0033365; GO:0034394; GO:0036309; GO:0036371; GO:0042383; GO:0043005; GO:0043034; GO:0043268; GO:0044325; GO:0045121; GO:0045211; GO:0050821; GO:0051117; GO:0051279; GO:0051597; GO:0051924; GO:0051928; GO:0055037; GO:0055117; GO:0060307; GO:0070296; GO:0070972; GO:0072659; GO:0086004; GO:0086005; GO:0086014; GO:0086015; GO:0086046; GO:0086066; GO:0086070; GO:0086091; GO:0098907; GO:0098910; GO:0140031; GO:1901018; GO:1901019; GO:1901021; GO:2001259 15100 XM_044314395.1 7 0 0 0 0 NA NA NA NA NA NA 15101 XM_029355833.2 454 628 163 262 452 I0IUP3 0 DNA helicase MCM8 (EC 3.6.4.12) (Minichromosome maintenance 8) Gallus gallus (Chicken) cellular response to DNA damage stimulus [GO:0006974]; DNA duplex unwinding [GO:0032508]; double-strand break repair via homologous recombination [GO:0000724] GO:0000724; GO:0003697; GO:0004386; GO:0005524; GO:0005634; GO:0006974; GO:0016887; GO:0032508; GO:0042555; GO:0097362 15102 XM_044321840.1 0 0 0 0 51 O95260 5.11e-123 Arginyl-tRNA--protein transferase 1 (Arginyltransferase 1) (R-transferase 1) (EC 2.3.2.8) (Arginine-tRNA--protein transferase 1) Homo sapiens (Human) proteasomal protein catabolic process [GO:0010498]; protein arginylation [GO:0016598] GO:0004057; GO:0005634; GO:0005737; GO:0010498; GO:0016598 15103 XR_006396683.1 3752 5029 2821 5553 2938 NA NA NA NA NA NA 15104 XR_006396706.1 0 0 0 42 0 NA NA NA NA NA NA 15105 XM_044321551.1 163 170 140 187 178 NA NA NA NA NA NA 15106 XM_044317316.1 69 727 9 1196 687 A0A2B4SES9 7.01e-83 NA NA NA NA 15107 XR_006396674.1 23 0 0 0 55 NA NA NA NA NA NA 15108 XM_044321973.1 132 53 0 121 51 O75486 8.66e-73 Transcription initiation protein SPT3 homolog (SPT3-like protein) Homo sapiens (Human) histone acetylation [GO:0016573]; histone H3 acetylation [GO:0043966]; monoubiquitinated histone deubiquitination [GO:0035521]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA repair [GO:0006282]; regulation of DNA-templated transcription [GO:0006355]; regulation of RNA splicing [GO:0043484]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366] GO:0000124; GO:0003713; GO:0005634; GO:0005654; GO:0006282; GO:0006355; GO:0006357; GO:0006366; GO:0016573; GO:0033276; GO:0035521; GO:0035522; GO:0043484; GO:0043966; GO:0045893; GO:0046982 15109 XM_029344845.2 107 88 49 157 113 Q6DIV6 1.05e-70 Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Solute carrier family 32 member 1) (Vesicular GABA transporter) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) beta-alanine transport [GO:0001762]; gamma-aminobutyric acid import [GO:0051939]; gamma-aminobutyric acid transport [GO:0015812]; glycine transport [GO:0015816]; neurotransmitter transport [GO:0006836] GO:0001762; GO:0006836; GO:0008021; GO:0015185; GO:0015187; GO:0015812; GO:0015816; GO:0030659; GO:0042995; GO:0051939; GO:0098793; GO:0140799; GO:0140800 15110 XM_029347617.2 132 6 41 94 133 Q8IS64 8.59e-149 Endothelin-converting enzyme homolog (ECE) (EC 3.4.24.-) Locusta migratoria (Migratory locust) proteolysis [GO:0006508] GO:0004175; GO:0004222; GO:0005886; GO:0006508; GO:0008270 15111 XM_029344942.2 48 46 46 37 54 NA NA NA NA NA NA 15112 XR_006397017.1 381 34 75 288 399 NA NA NA NA NA NA 15113 XR_003826754.2 25 10 4 8 13 NA NA NA NA NA NA 15114 XM_044308794.1 2962 2895 1250 2341 2319 Q8WW35 1.07e-46 Dynein light chain Tctex-type protein 2B (Tctex1 domain-containing protein 2) Homo sapiens (Human) cilium assembly [GO:0060271]; intraciliary retrograde transport [GO:0035721]; microtubule-based movement [GO:0007018]; regulation of cilium assembly [GO:1902017]; regulation of intraciliary retrograde transport [GO:1905799] GO:0005737; GO:0005868; GO:0005929; GO:0007018; GO:0035721; GO:0045505; GO:0060271; GO:0120293; GO:1902017; GO:1905799 15115 XM_044318600.1 430 239 206 289 333 Q9VXT2 1.69e-87 DnaJ homolog subfamily C member 25 homolog Drosophila melanogaster (Fruit fly) protein folding [GO:0006457] GO:0005789; GO:0006457; GO:0012505 15116 XM_044321042.1 111 0 12 69 25 C3ZQF9 5.65e-30 QRFP-like peptide receptor Branchiostoma floridae (Florida lancelet) (Amphioxus) cellular response to peptide [GO:1901653]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:1901653 15117 XR_006393832.1 17 69 22 15 73 NA NA NA NA NA NA 15118 XM_044323647.1 14 0 21 0 0 NA NA NA NA NA NA 15119 XM_044316933.1 114 45 60 43 167 NA NA NA NA NA NA 15120 XM_029335260.2 512 179 538 939 683 Q9PVY8 6.38e-57 Forkhead box protein C2-B (FoxC2-B) (FoxC2b) (Fork head domain-related protein 4') (FD-4') (xFD-4') (xFD4 B) Xenopus laevis (African clawed frog) mesoderm development [GO:0007498]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355] GO:0003677; GO:0003700; GO:0005634; GO:0006355; GO:0007498; GO:0043565; GO:0045893; GO:0045944; GO:1990841 15121 XM_029358155.2 1170 942 755 866 795 Q8NFH3 1.27e-88 Nucleoporin Nup43 (Nup107-160 subcomplex subunit Nup43) (p42) Homo sapiens (Human) cell division [GO:0051301]; chromosome segregation [GO:0007059]; mRNA transport [GO:0051028]; nucleocytoplasmic transport [GO:0006913]; protein transport [GO:0015031] GO:0000776; GO:0005635; GO:0005643; GO:0005654; GO:0005829; GO:0006913; GO:0007059; GO:0015031; GO:0016607; GO:0031080; GO:0051028; GO:0051301 15122 XM_044318933.1 2347 1314 1490 1964 2184 Q63569 0 26S proteasome regulatory subunit 6A (26S proteasome AAA-ATPase subunit RPT5) (Proteasome 26S subunit ATPase 3) (Spermatogenic cell/sperm-associated Tat-binding protein homolog SATA) (Tat-binding protein 1) (TBP-1) Rattus norvegicus (Rat) blastocyst development [GO:0001824]; modulation by host of viral transcription [GO:0043921]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] GO:0000502; GO:0000932; GO:0001824; GO:0005524; GO:0005634; GO:0005737; GO:0008540; GO:0016887; GO:0022624; GO:0036402; GO:0042802; GO:0043161; GO:0043921; GO:0045944; GO:0048471 15123 XM_044319291.1 21 12 16 14 99 NA NA NA NA NA NA 15124 XM_044322467.1 195 292 1 141 165 Q96AY4 1.76e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15125 XM_044322467.1 195 292 1 141 165 Q96AY4 4.6e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15126 XM_044322467.1 195 292 1 141 165 Q96AY4 8.04e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15127 XM_044319689.1 0 68 70 0 21 NA NA NA NA NA NA 15128 XR_006392173.1 0 16 13 10 6 NA NA NA NA NA NA 15129 XR_006392194.1 0 9 4 0 0 NA NA NA NA NA NA 15130 XM_044313479.1 0 0 0 8 41 NA NA NA NA NA NA 15131 XM_044322289.1 0 0 5 5 7 NA NA NA NA NA NA 15132 XR_006396040.1 433 764 648 805 252 NA NA NA NA NA NA 15133 XR_003823833.2 12 20 0 8 25 NA NA NA NA NA NA 15134 XM_029339301.2 36 33 10 19 72 Q8TA86 2.03e-60 Retinitis pigmentosa 9 protein (Pim-1-associated protein) (PAP-1) Homo sapiens (Human) cognition [GO:0050890]; RNA splicing [GO:0008380] GO:0003723; GO:0005634; GO:0005785; GO:0008380; GO:0046872; GO:0050890 15135 XM_044313711.1 926 610 241 180 158 NA NA NA NA NA NA 15136 XR_006395845.1 51 91 55 21 80 NA NA NA NA NA NA 15137 XM_044314686.1 542 528 315 382 828 Q1L8X9 6.6e-72 Vesicular glutamate transporter 3 (VGluT3) (Solute carrier family 17 member 8) Danio rerio (Zebrafish) (Brachydanio rerio) anion transport [GO:0006820]; equilibrioception [GO:0050957]; L-glutamate import [GO:0051938]; L-glutamate transmembrane transport [GO:0015813]; neurotransmitter loading into synaptic vesicle [GO:0098700]; phosphate ion homeostasis [GO:0055062]; positive regulation of glutamate uptake involved in transmission of nerve impulse [GO:0051951]; regulation of acetylcholine uptake [GO:0051631]; regulation of synapse structure or activity [GO:0050803]; sodium-dependent phosphate transport [GO:0044341]; synaptic transmission, glutamatergic [GO:0035249]; vestibular reflex [GO:0060005] GO:0005254; GO:0005313; GO:0005326; GO:0005436; GO:0005886; GO:0006820; GO:0015813; GO:0016020; GO:0022857; GO:0030672; GO:0034707; GO:0035249; GO:0043005; GO:0044341; GO:0050803; GO:0050957; GO:0051631; GO:0051938; GO:0051951; GO:0055062; GO:0060005; GO:0060076; GO:0098700; GO:0140788 15138 XM_044314686.1 542 528 315 382 828 Q1L8X9 1.7e-22 Vesicular glutamate transporter 3 (VGluT3) (Solute carrier family 17 member 8) Danio rerio (Zebrafish) (Brachydanio rerio) anion transport [GO:0006820]; equilibrioception [GO:0050957]; L-glutamate import [GO:0051938]; L-glutamate transmembrane transport [GO:0015813]; neurotransmitter loading into synaptic vesicle [GO:0098700]; phosphate ion homeostasis [GO:0055062]; positive regulation of glutamate uptake involved in transmission of nerve impulse [GO:0051951]; regulation of acetylcholine uptake [GO:0051631]; regulation of synapse structure or activity [GO:0050803]; sodium-dependent phosphate transport [GO:0044341]; synaptic transmission, glutamatergic [GO:0035249]; vestibular reflex [GO:0060005] GO:0005254; GO:0005313; GO:0005326; GO:0005436; GO:0005886; GO:0006820; GO:0015813; GO:0016020; GO:0022857; GO:0030672; GO:0034707; GO:0035249; GO:0043005; GO:0044341; GO:0050803; GO:0050957; GO:0051631; GO:0051938; GO:0051951; GO:0055062; GO:0060005; GO:0060076; GO:0098700; GO:0140788 15139 XM_044307534.1 0 58 0 0 0 NA NA NA NA NA NA 15140 XR_006394157.1 8 0 0 5 0 NA NA NA NA NA NA 15141 XM_044307598.1 8 0 0 2 5 B8VIU6 4.7e-46 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 15142 XM_044311478.1 6 4 6 9 6 NA NA NA NA NA NA 15143 XM_029340378.2 37 59 51 21 273 NA NA NA NA NA NA 15144 XR_006397132.1 16 0 2 7 11 NA NA NA NA NA NA 15145 XR_006395214.1 1 16 20 7 10 NA NA NA NA NA NA 15146 XM_029340008.2 438 400 358 309 185 Q5ZLX5 4.34e-56 Zinc finger Ran-binding domain-containing protein 2 Gallus gallus (Chicken) RNA processing [GO:0006396] GO:0001530; GO:0003723; GO:0005634; GO:0006396; GO:0046872 15147 XM_029330807.2 3238 2881 2260 1975 1736 NA NA NA NA NA NA 15148 XM_029330023.2 2114 2910 1872 1861 1737 P62321 2.64e-36 Small nuclear ribonucleoprotein F (snRNP-F) (Sm protein F) (Sm-F) (SmF) Xenopus laevis (African clawed frog) mRNA splicing, via spliceosome [GO:0000398]; spliceosomal snRNP assembly [GO:0000387] GO:0000387; GO:0000398; GO:0003723; GO:0005634; GO:0005685; GO:0005687; GO:0005829; GO:0034709; GO:0034715; GO:0034719; GO:0046540; GO:0071005; GO:0071007 15149 XM_029350726.2 75 53 81 79 95 NA NA NA NA NA NA 15150 XM_044315816.1 88 79 72 140 192 P31649 3.73e-158 Sodium- and chloride-dependent GABA transporter 2 (GAT-2) (Sodium- and chloride-dependent GABA transporter 3) (GAT-3) (Solute carrier family 6 member 13) Mus musculus (Mouse) amino acid import across plasma membrane [GO:0089718]; creatine transmembrane transport [GO:0015881]; gamma-aminobutyric acid import [GO:0051939]; monocarboxylic acid transport [GO:0015718]; neurotransmitter transport [GO:0006836]; nitrogen compound transport [GO:0071705]; positive regulation of necrotic cell death [GO:0010940]; sodium ion transmembrane transport [GO:0035725]; taurine transport [GO:0015734] GO:0005283; GO:0005308; GO:0005332; GO:0005368; GO:0005369; GO:0005886; GO:0006836; GO:0008028; GO:0010940; GO:0015171; GO:0015185; GO:0015718; GO:0015734; GO:0015881; GO:0016323; GO:0035725; GO:0042165; GO:0043005; GO:0051939; GO:0071705; GO:0089718 15151 XM_044319819.1 668 400 498 740 929 B8V7Q1 0 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 15152 XR_006397514.1 2950 1513 1745 4648 3081 NA NA NA NA NA NA 15153 XR_006397524.1 4 1 0 0 16 NA NA NA NA NA NA 15154 XM_029325351.2 0 6 0 0 0 NA NA NA NA NA NA 15155 XM_044318178.1 446 767 188 278 468 Q1T7B9 3.31e-25 Centromere protein M (CENP-M) Gallus gallus (Chicken) NA GO:0000775; GO:0005634 15156 XM_029354766.2 7 3 0 11 6 Q8QGQ6 3.35e-40 Circadian locomoter output cycles protein kaput Gallus gallus (Chicken) cellular response to DNA damage stimulus [GO:0006974]; circadian regulation of gene expression [GO:0032922]; protein acetylation [GO:0006473]; regulation of transcription by RNA polymerase II [GO:0006357]; response to redox state [GO:0051775] GO:0000978; GO:0000981; GO:0003677; GO:0005634; GO:0005829; GO:0006357; GO:0006473; GO:0006974; GO:0032922; GO:0046983; GO:0051775; GO:0070888; GO:1990513 15157 XR_003827161.2 29 14 19 12 41 NA NA NA NA NA NA 15158 XM_029346708.2 1156 1123 759 659 960 NA NA NA NA NA NA 15159 XM_044318875.1 203 145 343 721 593 Q9BSW2 2.66e-54 EF-hand calcium-binding domain-containing protein 4B (Calcium release-activated calcium channel regulator 2A) (CRAC channel regulator 2A) (Calcium release-activated channel regulator 2A) (Ras-related protein Rab-46) Homo sapiens (Human) activation of store-operated calcium channel activity [GO:0032237]; endosomal transport [GO:0016197]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of JNK cascade [GO:0046330]; response to histamine [GO:0034776]; store-operated calcium entry [GO:0002115]; T-helper 1 cell differentiation [GO:0045063] GO:0000139; GO:0001772; GO:0002115; GO:0003924; GO:0005509; GO:0005525; GO:0005576; GO:0005737; GO:0005815; GO:0005886; GO:0016020; GO:0016197; GO:0031982; GO:0032237; GO:0032588; GO:0033093; GO:0034776; GO:0035580; GO:0045063; GO:0046330; GO:0051928 15160 XR_003824107.2 491 498 459 218 248 NA NA NA NA NA NA 15161 XR_006391588.1 59 53 10 39 102 NA NA NA NA NA NA 15162 XM_029339565.2 353 380 255 375 377 Q0V9S9 0 Dynein regulatory complex subunit 7 (Coiled-coil domain-containing protein 135) (Coiled-coil domain-containing protein lobo homolog) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) flagellated sperm motility [GO:0030317]; sperm axoneme assembly [GO:0007288]; spermatogenesis [GO:0007283] GO:0005737; GO:0005856; GO:0007283; GO:0007288; GO:0030317; GO:0031514 15163 XM_029331137.2 4 0 15 3 32 P78357 7.88e-32 Contactin-associated protein 1 (Caspr) (Caspr1) (Neurexin IV) (Neurexin-4) (p190) Homo sapiens (Human) axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cytoskeleton organization [GO:0007010]; mitochondrion organization [GO:0007005]; myelination in peripheral nervous system [GO:0022011]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; neuron projection morphogenesis [GO:0048812]; neuronal action potential propagation [GO:0019227]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; postsynaptic density organization [GO:0097106]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; regulation of synapse maturation [GO:0090128]; signal transduction [GO:0007165] GO:0002175; GO:0005886; GO:0007005; GO:0007010; GO:0007155; GO:0007165; GO:0007409; GO:0016020; GO:0017124; GO:0019227; GO:0022010; GO:0022011; GO:0030913; GO:0033010; GO:0033270; GO:0038023; GO:0048786; GO:0048812; GO:0050884; GO:0050885; GO:0071205; GO:0090128; GO:0097106; GO:0098529; GO:0098978; GO:1990227 15164 XM_044316207.1 7 0 93 31 52 NA NA NA NA NA NA 15165 XM_029330020.2 411 499 297 280 438 Q9NPL8 3.94e-25 Complex I assembly factor TIMMDC1, mitochondrial (Protein M5-14) (Translocase of inner mitochondrial membrane domain-containing protein 1) (TIMM domain containing-protein 1) Homo sapiens (Human) NA GO:0005654; GO:0005739; GO:0005743 15166 XM_044327466.1 3 4 4 28 25 NA NA NA NA NA NA 15167 XM_044307685.1 379 120 102 194 127 NA NA NA NA NA NA 15168 XR_006392278.1 19 16 25 0 16 NA NA NA NA NA NA 15169 XM_029345182.2 2134 1231 1703 1100 1679 Q99P75 2.82e-68 Ras-related protein Rab-9A Rattus norvegicus (Rat) negative regulation by host of symbiont catalytic activity [GO:0052403]; positive regulation of exocytosis [GO:0045921]; protein transport [GO:0015031]; Rab protein signal transduction [GO:0032482]; regulation of protein localization [GO:0032880]; retrograde transport, endosome to Golgi [GO:0042147] GO:0000139; GO:0003924; GO:0005525; GO:0005764; GO:0005770; GO:0005789; GO:0005829; GO:0005886; GO:0015031; GO:0019003; GO:0030659; GO:0030670; GO:0032482; GO:0032880; GO:0042147; GO:0042470; GO:0042802; GO:0045335; GO:0045921; GO:0052403 15170 XR_006393728.1 21 0 20 19 25 NA NA NA NA NA NA 15171 XM_044328403.1 0 0 0 0 9 Q8BVV7 2.44e-58 Centrosomal protein of 95 kDa (Cep95) (Coiled-coil domain-containing protein 45) Mus musculus (Mouse) NA GO:0000922; GO:0005737; GO:0005813 15172 XM_044318982.1 67 16 87 12 28 B6CJY5 1.02e-79 TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6) Macaca mulatta (Rhesus macaque) activation of NF-kappaB-inducing kinase activity [GO:0007250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; bone resorption [GO:0045453]; cellular response to DNA damage stimulus [GO:0006974]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; in utero embryonic development [GO:0001701]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-17-mediated signaling pathway [GO:0097400]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin production [GO:0002637]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000122; GO:0001503; GO:0001701; GO:0001843; GO:0002637; GO:0002726; GO:0004842; GO:0005164; GO:0005634; GO:0005811; GO:0005829; GO:0005938; GO:0006974; GO:0007249; GO:0007250; GO:0008270; GO:0009898; GO:0019886; GO:0030316; GO:0031435; GO:0031624; GO:0031625; GO:0031663; GO:0031666; GO:0031996; GO:0032735; GO:0032743; GO:0032755; GO:0032813; GO:0033209; GO:0035631; GO:0042088; GO:0042102; GO:0042475; GO:0042802; GO:0042826; GO:0042981; GO:0043011; GO:0043122; GO:0043123; GO:0043422; GO:0043507; GO:0045453; GO:0045672; GO:0045944; GO:0046330; GO:0047485; GO:0048471; GO:0050852; GO:0051092; GO:0051865; GO:0061630; GO:0070498; GO:0070534; GO:0097400; GO:1901224; GO:1904996; GO:2000679 15173 XM_029333387.2 0 351 0 329 300 Q5EBF1 0 Cytosolic purine 5'-nucleotidase (EC 3.1.3.5) (EC 3.1.3.99) (Cytosolic nucleoside phosphotransferase 5'N) (EC 2.7.1.77) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) dGMP metabolic process [GO:0046054]; GMP metabolic process [GO:0046037]; IMP metabolic process [GO:0046040] GO:0005524; GO:0005829; GO:0008253; GO:0042802; GO:0046037; GO:0046040; GO:0046054; GO:0046872; GO:0050146; GO:0050483; GO:0050484; GO:0106411 15174 XM_029335096.2 47569 118662 59173 45571 34872 B4PEU8 4.53e-109 40S ribosomal protein S9 Drosophila yakuba (Fruit fly) translation [GO:0006412] GO:0000228; GO:0003735; GO:0005730; GO:0006412; GO:0015935; GO:0019843; GO:0022626 15175 XM_029348597.2 12 0 182 5 0 Q5RE70 0 Integrator complex subunit 3 (Int3) (SOSS complex subunit A) (Sensor of single-strand DNA complex subunit A) (SOSS-A) (Sensor of ssDNA subunit A) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; mitotic G2/M transition checkpoint [GO:0044818]; response to ionizing radiation [GO:0010212] GO:0005634; GO:0005737; GO:0006281; GO:0006974; GO:0010212; GO:0044818; GO:0070876 15176 XR_006392351.1 24 0 22 51 16 P0C0R5 2.85e-133 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) Rattus norvegicus (Rat) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006623; GO:0010506; GO:0015630; GO:0016236; GO:0016241; GO:0030242; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 15177 XR_006392351.1 24 0 22 51 16 P0C0R5 4.66e-79 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) Rattus norvegicus (Rat) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006623; GO:0010506; GO:0015630; GO:0016236; GO:0016241; GO:0030242; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 15178 XR_006392351.1 24 0 22 51 16 P0C0R5 4.66e-79 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) Rattus norvegicus (Rat) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006623; GO:0010506; GO:0015630; GO:0016236; GO:0016241; GO:0030242; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 15179 XR_006392351.1 24 0 22 51 16 P0C0R5 4.66e-79 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) Rattus norvegicus (Rat) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006623; GO:0010506; GO:0015630; GO:0016236; GO:0016241; GO:0030242; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 15180 XM_044325611.1 59 0 15 0 29 NA NA NA NA NA NA 15181 XM_044326507.1 297 227 112 457 269 O15427 6.95e-31 Monocarboxylate transporter 4 (MCT 4) (Solute carrier family 16 member 3) Homo sapiens (Human) lactate transmembrane transport [GO:0035873]; monocarboxylic acid transport [GO:0015718]; plasma membrane lactate transport [GO:0035879]; protein catabolic process [GO:0030163]; pyruvate catabolic process [GO:0042867]; pyruvate transmembrane transport [GO:1901475] GO:0003723; GO:0005886; GO:0008028; GO:0015650; GO:0015718; GO:0016020; GO:0016323; GO:0016324; GO:0016328; GO:0030163; GO:0031965; GO:0035873; GO:0035879; GO:0042867; GO:0045202; GO:0050833; GO:0098688; GO:0098839; GO:1901475 15182 XM_029356719.2 0 0 158 68 0 Q58DG1 1.38e-144 MYG1 exonuclease (EC 3.1.-.-) Bos taurus (Bovine) locomotory exploration behavior [GO:0035641] GO:0004518; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005739; GO:0005759; GO:0035641 15183 XM_029327573.2 86 103 68 112 175 NA NA NA NA NA NA 15184 XM_029341848.2 10553 12274 7803 12084 7015 B0VYY5 6.54e-45 Cytochrome c oxidase subunit 5A, mitochondrial (Cytochrome c oxidase polypeptide Va) Notamacropus parma (Parma wallaby) (Macropus parma) mitochondrial electron transport, cytochrome c to oxygen [GO:0006123] GO:0005751; GO:0006123; GO:0046872 15185 XM_044317987.1 19 14 30 33 27 NA NA NA NA NA NA 15186 XM_029341675.2 463 60 72 279 229 F1NWE3 3.94e-143 Receptor-type tyrosine-protein phosphatase S (R-PTP-S) (EC 3.1.3.48) (Chick receptor tyrosine phosphatase alpha) (CRYP alpha) (CRYPalpha) Gallus gallus (Chicken) negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; synaptic membrane adhesion [GO:0099560] GO:0004725; GO:0005886; GO:0006470; GO:0008201; GO:0030424; GO:0030426; GO:0030517; GO:0030672; GO:0035335; GO:0042803; GO:0043204; GO:0043395; GO:0048671; GO:0048681; GO:0061000; GO:0098839; GO:0099560 15187 XR_006395835.1 0 0 12 0 15 NA NA NA NA NA NA 15188 XM_044308340.1 311 47 91 172 179 P0C5Y8 0 Alsin (Amyotrophic lateral sclerosis 2 protein homolog) Rattus norvegicus (Rat) axonogenesis [GO:0007409]; behavioral fear response [GO:0001662]; cell death [GO:0008219]; endosomal transport [GO:0016197]; endosome organization [GO:0007032]; in utero embryonic development [GO:0001701]; locomotory behavior [GO:0007626]; lysosomal transport [GO:0007041]; neuromuscular junction development [GO:0007528]; neuron projection morphogenesis [GO:0048812]; positive regulation of GTPase activity [GO:0043547]; positive regulation of protein kinase activity [GO:0045860]; protein homooligomerization [GO:0051260]; protein localization [GO:0008104]; Rac protein signal transduction [GO:0016601]; receptor recycling [GO:0001881]; regulation of endosome size [GO:0051036]; regulation of GTPase activity [GO:0043087]; response to oxidative stress [GO:0006979]; synaptic transmission, glutamatergic [GO:0035249]; vesicle organization [GO:0016050] GO:0001662; GO:0001701; GO:0001726; GO:0001881; GO:0005085; GO:0005096; GO:0005634; GO:0005737; GO:0005769; GO:0005813; GO:0005829; GO:0006979; GO:0007032; GO:0007041; GO:0007409; GO:0007528; GO:0007626; GO:0008104; GO:0008219; GO:0014069; GO:0016020; GO:0016050; GO:0016197; GO:0016601; GO:0030027; GO:0030424; GO:0030425; GO:0030426; GO:0031267; GO:0031982; GO:0032991; GO:0035249; GO:0042802; GO:0042803; GO:0043005; GO:0043025; GO:0043087; GO:0043197; GO:0043231; GO:0043539; GO:0043547; GO:0045202; GO:0045860; GO:0048812; GO:0051036; GO:0051260 15189 XM_044308340.1 311 47 91 172 179 P0C5Y8 2.34e-27 Alsin (Amyotrophic lateral sclerosis 2 protein homolog) Rattus norvegicus (Rat) axonogenesis [GO:0007409]; behavioral fear response [GO:0001662]; cell death [GO:0008219]; endosomal transport [GO:0016197]; endosome organization [GO:0007032]; in utero embryonic development [GO:0001701]; locomotory behavior [GO:0007626]; lysosomal transport [GO:0007041]; neuromuscular junction development [GO:0007528]; neuron projection morphogenesis [GO:0048812]; positive regulation of GTPase activity [GO:0043547]; positive regulation of protein kinase activity [GO:0045860]; protein homooligomerization [GO:0051260]; protein localization [GO:0008104]; Rac protein signal transduction [GO:0016601]; receptor recycling [GO:0001881]; regulation of endosome size [GO:0051036]; regulation of GTPase activity [GO:0043087]; response to oxidative stress [GO:0006979]; synaptic transmission, glutamatergic [GO:0035249]; vesicle organization [GO:0016050] GO:0001662; GO:0001701; GO:0001726; GO:0001881; GO:0005085; GO:0005096; GO:0005634; GO:0005737; GO:0005769; GO:0005813; GO:0005829; GO:0006979; GO:0007032; GO:0007041; GO:0007409; GO:0007528; GO:0007626; GO:0008104; GO:0008219; GO:0014069; GO:0016020; GO:0016050; GO:0016197; GO:0016601; GO:0030027; GO:0030424; GO:0030425; GO:0030426; GO:0031267; GO:0031982; GO:0032991; GO:0035249; GO:0042802; GO:0042803; GO:0043005; GO:0043025; GO:0043087; GO:0043197; GO:0043231; GO:0043539; GO:0043547; GO:0045202; GO:0045860; GO:0048812; GO:0051036; GO:0051260 15190 XR_003825248.2 55 10 40 0 261 NA NA NA NA NA NA 15191 XM_029335994.2 545 397 199 304 217 Q4R8G6 5.62e-117 Meiosis-specific with OB domain-containing protein (EC 3.1.-.-) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) double-strand break repair via homologous recombination [GO:0000724]; female meiosis I [GO:0007144]; fertilization [GO:0009566]; homologous chromosome pairing at meiosis [GO:0007129]; male meiotic nuclear division [GO:0007140]; resolution of meiotic recombination intermediates [GO:0000712] GO:0000712; GO:0000724; GO:0003682; GO:0003697; GO:0005634; GO:0005694; GO:0005737; GO:0007129; GO:0007140; GO:0007144; GO:0008310; GO:0009566 15192 XM_044310223.1 46 10 84 15 158 NA NA NA NA NA NA 15193 XM_029326871.2 731 1185 706 1129 740 A4FV08 1.86e-154 Glucosamine-6-phosphate isomerase 1 (EC 3.5.99.6) (Glucosamine-6-phosphate deaminase 1) (GNPDA 1) (GlcN6P deaminase 1) (Oscillin) Bos taurus (Bovine) carbohydrate metabolic process [GO:0005975]; generation of precursor metabolites and energy [GO:0006091]; glucosamine catabolic process [GO:0006043]; N-acetylglucosamine catabolic process [GO:0006046]; N-acetylneuraminate catabolic process [GO:0019262]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048] GO:0004342; GO:0005737; GO:0005975; GO:0006043; GO:0006046; GO:0006048; GO:0006091; GO:0016853; GO:0019262; GO:0042802 15194 XM_044314657.1 7 1 7 18 2 NA NA NA NA NA NA 15195 XM_029352600.2 8 0 5 4 40 NA NA NA NA NA NA 15196 XM_044322201.1 0 0 35 0 9 Q7LL04 1e-32 UPF0676 protein C1494.01 Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) NA GO:0005634; GO:0005829 15197 XM_044318161.1 44 19 21 23 63 NA NA NA NA NA NA 15198 XM_044306754.1 54 172 126 165 124 NA NA NA NA NA NA 15199 XR_006396992.1 1 18 1 0 76 NA NA NA NA NA NA 15200 XM_029334746.2 4867 6567 4328 8841 5607 P79145 7.59e-33 cAMP-responsive element modulator Canis lupus familiaris (Dog) (Canis familiaris) regulation of transcription by RNA polymerase II [GO:0006357]; response to stimulus [GO:0050896] GO:0000978; GO:0000981; GO:0001227; GO:0005667; GO:0006357; GO:0050896; GO:1990589 15201 XM_044314464.1 249 7 0 0 0 NA NA NA NA NA NA 15202 XM_044321631.1 76 24 18 42 120 P49914 2.9e-56 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) (5,10-methenyl-tetrahydrofolate synthetase) (MTHFS) (Methenyl-THF synthetase) Homo sapiens (Human) folic acid catabolic process [GO:0046657]; folic acid metabolic process [GO:0046655]; folic acid-containing compound biosynthetic process [GO:0009396]; formate metabolic process [GO:0015942]; glutamate metabolic process [GO:0006536]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653] GO:0005524; GO:0005542; GO:0005737; GO:0005739; GO:0005759; GO:0005829; GO:0006536; GO:0009396; GO:0015942; GO:0030272; GO:0035999; GO:0046653; GO:0046655; GO:0046657; GO:0046872 15203 XM_029358573.2 42 0 197 155 212 Q9R088 7.22e-63 Thymidine kinase 2, mitochondrial (EC 2.7.1.21) (2'-deoxyuridine kinase TK2) (EC 2.7.1.74) (Deoxycytidine kinase TK2) (EC 2.7.1.-) (Mt-TK) Mus musculus (Mouse) deoxycytidine metabolic process [GO:0046092]; deoxyribonucleotide metabolic process [GO:0009262]; DNA biosynthetic process [GO:0071897]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA replication [GO:0006264]; phosphorylation [GO:0016310]; thymidine metabolic process [GO:0046104] GO:0004137; GO:0004797; GO:0005524; GO:0005737; GO:0005739; GO:0005743; GO:0006264; GO:0009262; GO:0016310; GO:0019136; GO:0032042; GO:0046092; GO:0046104; GO:0071897 15204 XM_044313793.1 0 10 3 4 3 NA NA NA NA NA NA 15205 XM_029333054.2 24 14 35 32 71 Q2T9T9 7.81e-55 F-box/WD repeat-containing protein 9 (F-box and WD-40 domain-containing protein 9) Bos taurus (Bovine) NA NA 15206 XM_029331365.2 568 968 773 540 315 Q6P1S2 2.39e-26 Protein C3orf33 (Protein AC3-33) Homo sapiens (Human) negative regulation of ERK1 and ERK2 cascade [GO:0070373]; regulation of DNA-binding transcription factor activity [GO:0051090] GO:0005615; GO:0016020; GO:0051090; GO:0070373 15207 XM_029341253.2 258 140 130 81 136 Q804R0 1.29e-33 Transcription factor LBX2 (Ladybird homeobox 2) (Ladybird homeobox protein homolog 2) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic axis specification [GO:0000578]; muscle cell development [GO:0055001]; muscle cell differentiation [GO:0042692]; positive regulation of convergent extension involved in gastrulation [GO:1904105]; positive regulation of non-canonical Wnt signaling pathway [GO:2000052]; posterior lateral line neuromast deposition [GO:0048922]; posterior lateral line neuromast primordium migration [GO:0048920]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000578; GO:0000981; GO:0005634; GO:0006357; GO:0042692; GO:0048920; GO:0048922; GO:0055001; GO:0060828; GO:1904105; GO:1990837; GO:2000052 15208 XM_044326015.1 0 17 0 70 0 Q01484 0 Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin) Homo sapiens (Human) atrial cardiac muscle cell action potential [GO:0086014]; atrial cardiac muscle cell to AV node cell communication [GO:0086066]; atrial septum development [GO:0003283]; cellular calcium ion homeostasis [GO:0006874]; endocytosis [GO:0006897]; membrane depolarization during SA node cell action potential [GO:0086046]; paranodal junction assembly [GO:0030913]; positive regulation of calcium ion transmembrane transporter activity [GO:1901021]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cation channel activity [GO:2001259]; positive regulation of gene expression [GO:0010628]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to endoplasmic reticulum [GO:0070972]; protein localization to M-band [GO:0036309]; protein localization to organelle [GO:0033365]; protein localization to plasma membrane [GO:0072659]; protein localization to T-tubule [GO:0036371]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; regulation of atrial cardiac muscle cell action potential [GO:0098910]; regulation of calcium ion transmembrane transporter activity [GO:1901019]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of heart rate [GO:0002027]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of protein stability [GO:0031647]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of SA node cell action potential [GO:0098907]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; response to methylmercury [GO:0051597]; SA node cell action potential [GO:0086015]; SA node cell to atrial cardiac muscle cell communication [GO:0086070]; sarcoplasmic reticulum calcium ion transport [GO:0070296]; T-tubule organization [GO:0033292]; ventricular cardiac muscle cell action potential [GO:0086005] GO:0002027; GO:0003283; GO:0005200; GO:0005739; GO:0005764; GO:0005769; GO:0005829; GO:0005856; GO:0005886; GO:0006874; GO:0006897; GO:0008093; GO:0008104; GO:0010628; GO:0010881; GO:0010882; GO:0014704; GO:0015031; GO:0016323; GO:0016324; GO:0019899; GO:0019901; GO:0030018; GO:0030315; GO:0030507; GO:0030674; GO:0030913; GO:0031430; GO:0031647; GO:0031672; GO:0033292; GO:0033365; GO:0034394; GO:0036309; GO:0036371; GO:0042383; GO:0043005; GO:0043034; GO:0043268; GO:0044325; GO:0045121; GO:0045211; GO:0050821; GO:0051117; GO:0051279; GO:0051597; GO:0051924; GO:0051928; GO:0055037; GO:0055117; GO:0060307; GO:0070296; GO:0070972; GO:0072659; GO:0086004; GO:0086005; GO:0086014; GO:0086015; GO:0086046; GO:0086066; GO:0086070; GO:0086091; GO:0098907; GO:0098910; GO:0140031; GO:1901018; GO:1901019; GO:1901021; GO:2001259 15209 XM_044326015.1 0 17 0 70 0 Q01484 1.19e-105 Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin) Homo sapiens (Human) atrial cardiac muscle cell action potential [GO:0086014]; atrial cardiac muscle cell to AV node cell communication [GO:0086066]; atrial septum development [GO:0003283]; cellular calcium ion homeostasis [GO:0006874]; endocytosis [GO:0006897]; membrane depolarization during SA node cell action potential [GO:0086046]; paranodal junction assembly [GO:0030913]; positive regulation of calcium ion transmembrane transporter activity [GO:1901021]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cation channel activity [GO:2001259]; positive regulation of gene expression [GO:0010628]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to endoplasmic reticulum [GO:0070972]; protein localization to M-band [GO:0036309]; protein localization to organelle [GO:0033365]; protein localization to plasma membrane [GO:0072659]; protein localization to T-tubule [GO:0036371]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; regulation of atrial cardiac muscle cell action potential [GO:0098910]; regulation of calcium ion transmembrane transporter activity [GO:1901019]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of heart rate [GO:0002027]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of protein stability [GO:0031647]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of SA node cell action potential [GO:0098907]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; response to methylmercury [GO:0051597]; SA node cell action potential [GO:0086015]; SA node cell to atrial cardiac muscle cell communication [GO:0086070]; sarcoplasmic reticulum calcium ion transport [GO:0070296]; T-tubule organization [GO:0033292]; ventricular cardiac muscle cell action potential [GO:0086005] GO:0002027; GO:0003283; GO:0005200; GO:0005739; GO:0005764; GO:0005769; GO:0005829; GO:0005856; GO:0005886; GO:0006874; GO:0006897; GO:0008093; GO:0008104; GO:0010628; GO:0010881; GO:0010882; GO:0014704; GO:0015031; GO:0016323; GO:0016324; GO:0019899; GO:0019901; GO:0030018; GO:0030315; GO:0030507; GO:0030674; GO:0030913; GO:0031430; GO:0031647; GO:0031672; GO:0033292; GO:0033365; GO:0034394; GO:0036309; GO:0036371; GO:0042383; GO:0043005; GO:0043034; GO:0043268; GO:0044325; GO:0045121; GO:0045211; GO:0050821; GO:0051117; GO:0051279; GO:0051597; GO:0051924; GO:0051928; GO:0055037; GO:0055117; GO:0060307; GO:0070296; GO:0070972; GO:0072659; GO:0086004; GO:0086005; GO:0086014; GO:0086015; GO:0086046; GO:0086066; GO:0086070; GO:0086091; GO:0098907; GO:0098910; GO:0140031; GO:1901018; GO:1901019; GO:1901021; GO:2001259 15210 XM_044326015.1 0 17 0 70 0 Q01484 1.12e-103 Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin) Homo sapiens (Human) atrial cardiac muscle cell action potential [GO:0086014]; atrial cardiac muscle cell to AV node cell communication [GO:0086066]; atrial septum development [GO:0003283]; cellular calcium ion homeostasis [GO:0006874]; endocytosis [GO:0006897]; membrane depolarization during SA node cell action potential [GO:0086046]; paranodal junction assembly [GO:0030913]; positive regulation of calcium ion transmembrane transporter activity [GO:1901021]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cation channel activity [GO:2001259]; positive regulation of gene expression [GO:0010628]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to endoplasmic reticulum [GO:0070972]; protein localization to M-band [GO:0036309]; protein localization to organelle [GO:0033365]; protein localization to plasma membrane [GO:0072659]; protein localization to T-tubule [GO:0036371]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; regulation of atrial cardiac muscle cell action potential [GO:0098910]; regulation of calcium ion transmembrane transporter activity [GO:1901019]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of heart rate [GO:0002027]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of protein stability [GO:0031647]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of SA node cell action potential [GO:0098907]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; response to methylmercury [GO:0051597]; SA node cell action potential [GO:0086015]; SA node cell to atrial cardiac muscle cell communication [GO:0086070]; sarcoplasmic reticulum calcium ion transport [GO:0070296]; T-tubule organization [GO:0033292]; ventricular cardiac muscle cell action potential [GO:0086005] GO:0002027; GO:0003283; GO:0005200; GO:0005739; GO:0005764; GO:0005769; GO:0005829; GO:0005856; GO:0005886; GO:0006874; GO:0006897; GO:0008093; GO:0008104; GO:0010628; GO:0010881; GO:0010882; GO:0014704; GO:0015031; GO:0016323; GO:0016324; GO:0019899; GO:0019901; GO:0030018; GO:0030315; GO:0030507; GO:0030674; GO:0030913; GO:0031430; GO:0031647; GO:0031672; GO:0033292; GO:0033365; GO:0034394; GO:0036309; GO:0036371; GO:0042383; GO:0043005; GO:0043034; GO:0043268; GO:0044325; GO:0045121; GO:0045211; GO:0050821; GO:0051117; GO:0051279; GO:0051597; GO:0051924; GO:0051928; GO:0055037; GO:0055117; GO:0060307; GO:0070296; GO:0070972; GO:0072659; GO:0086004; GO:0086005; GO:0086014; GO:0086015; GO:0086046; GO:0086066; GO:0086070; GO:0086091; GO:0098907; GO:0098910; GO:0140031; GO:1901018; GO:1901019; GO:1901021; GO:2001259 15211 XM_044326015.1 0 17 0 70 0 Q01484 1.65e-46 Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin) Homo sapiens (Human) atrial cardiac muscle cell action potential [GO:0086014]; atrial cardiac muscle cell to AV node cell communication [GO:0086066]; atrial septum development [GO:0003283]; cellular calcium ion homeostasis [GO:0006874]; endocytosis [GO:0006897]; membrane depolarization during SA node cell action potential [GO:0086046]; paranodal junction assembly [GO:0030913]; positive regulation of calcium ion transmembrane transporter activity [GO:1901021]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cation channel activity [GO:2001259]; positive regulation of gene expression [GO:0010628]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to endoplasmic reticulum [GO:0070972]; protein localization to M-band [GO:0036309]; protein localization to organelle [GO:0033365]; protein localization to plasma membrane [GO:0072659]; protein localization to T-tubule [GO:0036371]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; regulation of atrial cardiac muscle cell action potential [GO:0098910]; regulation of calcium ion transmembrane transporter activity [GO:1901019]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of heart rate [GO:0002027]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of protein stability [GO:0031647]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of SA node cell action potential [GO:0098907]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; response to methylmercury [GO:0051597]; SA node cell action potential [GO:0086015]; SA node cell to atrial cardiac muscle cell communication [GO:0086070]; sarcoplasmic reticulum calcium ion transport [GO:0070296]; T-tubule organization [GO:0033292]; ventricular cardiac muscle cell action potential [GO:0086005] GO:0002027; GO:0003283; GO:0005200; GO:0005739; GO:0005764; GO:0005769; GO:0005829; GO:0005856; GO:0005886; GO:0006874; GO:0006897; GO:0008093; GO:0008104; GO:0010628; GO:0010881; GO:0010882; GO:0014704; GO:0015031; GO:0016323; GO:0016324; GO:0019899; GO:0019901; GO:0030018; GO:0030315; GO:0030507; GO:0030674; GO:0030913; GO:0031430; GO:0031647; GO:0031672; GO:0033292; GO:0033365; GO:0034394; GO:0036309; GO:0036371; GO:0042383; GO:0043005; GO:0043034; GO:0043268; GO:0044325; GO:0045121; GO:0045211; GO:0050821; GO:0051117; GO:0051279; GO:0051597; GO:0051924; GO:0051928; GO:0055037; GO:0055117; GO:0060307; GO:0070296; GO:0070972; GO:0072659; GO:0086004; GO:0086005; GO:0086014; GO:0086015; GO:0086046; GO:0086066; GO:0086070; GO:0086091; GO:0098907; GO:0098910; GO:0140031; GO:1901018; GO:1901019; GO:1901021; GO:2001259 15212 XM_029348051.2 319 960 464 296 130 NA NA NA NA NA NA 15213 XM_044307863.1 0 0 0 66 0 Q92113 5.75e-142 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Squalus acanthias (Spiny dogfish) steroid biosynthetic process [GO:0006694] GO:0004508; GO:0005506; GO:0006694; GO:0016020; GO:0020037; GO:0047442 15214 XM_029327829.2 14 61 29 1141 787 Q5ZL23 2.38e-66 Amyloid beta A4 precursor protein-binding family B member 1-interacting protein (APBB1-interacting protein 1) Gallus gallus (Chicken) signal transduction [GO:0007165] GO:0005829; GO:0005856; GO:0005886; GO:0007165 15215 XM_029332728.2 2393 3614 1695 1960 1267 Q8R0X2 7.15e-67 CDK2-associated and cullin domain-containing protein 1 Mus musculus (Mouse) G1/S transition of mitotic cell cycle [GO:0000082]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of protein kinase activity [GO:0045860]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000082; GO:0006511; GO:0008284; GO:0019901; GO:0031625; GO:0045860 15216 XM_029344271.2 1390 1212 903 1168 815 Q3UK78 6.02e-53 Polycomb group RING finger protein 5 (RING finger protein 159) Mus musculus (Mouse) histone H2A-K119 monoubiquitination [GO:0036353]; inactivation of X chromosome by genomic imprinting [GO:0060819]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0005634; GO:0005654; GO:0005794; GO:0005813; GO:0006357; GO:0031519; GO:0035102; GO:0036353; GO:0045944; GO:0046872; GO:0060819 15217 XM_029346701.2 469 307 129 220 363 P43450 3.1e-168 Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) Carassius auratus (Goldfish) cell cycle [GO:0007049]; cell division [GO:0051301]; protein phosphorylation [GO:0006468] GO:0004693; GO:0005524; GO:0006468; GO:0007049; GO:0051301; GO:0097472; GO:0106310 15218 XM_044314504.1 294 77 102 34 160 Q9CUX1 1.9e-47 52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (THAP domain-containing protein 0) (THAP domain-containing protein 12) Mus musculus (Mouse) NA GO:0003677; GO:0005634; GO:0046872; GO:0046983 15219 XM_044327623.1 14 5 2 0 7 Q5R6J3 5.28e-109 Solute carrier family 35 member F5 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0016020 15220 XM_044309778.1 30 52 45 35 42 NA NA NA NA NA NA 15221 XM_029343103.2 8614 8158 3981 4727 7088 P46222 4.03e-104 60S ribosomal protein L11 Drosophila melanogaster (Fruit fly) cytoplasmic translation [GO:0002181] GO:0002181; GO:0003723; GO:0003735; GO:0005730; GO:0005737; GO:0019843; GO:0022625; GO:0022626 15222 XR_006391888.1 2 9 0 17 10 NA NA NA NA NA NA 15223 XM_044319150.1 87 24 81 82 33 NA NA NA NA NA NA 15224 XR_006398191.1 0 9 0 11 12 NA NA NA NA NA NA 15225 XM_044323578.1 386 322 523 318 707 NA NA NA NA NA NA 15226 XM_029347777.2 767 216 383 11 182 Q15643 2.06e-38 Thyroid receptor-interacting protein 11 (TR-interacting protein 11) (TRIP-11) (Clonal evolution-related gene on chromosome 14 protein) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) Homo sapiens (Human) cartilage development [GO:0051216]; chondrocyte differentiation involved in endochondral bone morphogenesis [GO:0003413]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; Golgi ribbon formation [GO:0090161]; inner ear receptor cell stereocilium organization [GO:0060122]; protein glycosylation [GO:0006486]; transcription by RNA polymerase II [GO:0006366]; ventricular septum development [GO:0003281]; vesicle tethering to Golgi [GO:0099041] GO:0000139; GO:0002079; GO:0002081; GO:0003281; GO:0003413; GO:0003713; GO:0005654; GO:0005793; GO:0005794; GO:0005801; GO:0005856; GO:0006366; GO:0006486; GO:0006888; GO:0007030; GO:0016607; GO:0030133; GO:0031267; GO:0033116; GO:0051216; GO:0060122; GO:0090161; GO:0099041 15227 XM_044324400.1 0 0 24 0 0 P35546 1.54e-52 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; anatomical structure morphogenesis [GO:0009653]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006919; GO:0007156; GO:0007158; GO:0007169; GO:0007399; GO:0009410; GO:0009653; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030182; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0098797; GO:2001241 15228 XM_044324400.1 0 0 24 0 0 P35546 1.54e-52 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; anatomical structure morphogenesis [GO:0009653]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006919; GO:0007156; GO:0007158; GO:0007169; GO:0007399; GO:0009410; GO:0009653; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030182; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0098797; GO:2001241 15229 XM_044315144.1 16 6 0 0 2 NA NA NA NA NA NA 15230 XM_044328827.1 0 5 0 0 20 NA NA NA NA NA NA 15231 XM_029341308.2 0 118 156 498 112 Q91YJ5 5.6e-165 Translation initiation factor IF-2, mitochondrial (IF-2(Mt)) (IF-2Mt) (IF2(mt)) Mus musculus (Mouse) mitochondrial translational initiation [GO:0070124]; ribosome disassembly [GO:0032790]; translational initiation [GO:0006413] GO:0003743; GO:0003924; GO:0005525; GO:0005654; GO:0005737; GO:0005739; GO:0006413; GO:0008135; GO:0032790; GO:0043024; GO:0070124 15232 XM_044318772.1 33 26 25 0 17 NA NA NA NA NA NA 15233 XM_044324769.1 34 120 122 397 121 P35546 1.44e-80 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; anatomical structure morphogenesis [GO:0009653]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006919; GO:0007156; GO:0007158; GO:0007169; GO:0007399; GO:0009410; GO:0009653; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030182; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0098797; GO:2001241 15234 XM_029335930.2 43 0 0 27 0 Q2XWK0 1.17e-99 Synaptic vesicle 2-related protein (SV2-related protein) Xenopus laevis (African clawed frog) NA GO:0022857; GO:0030672 15235 XM_029357869.2 842 766 530 832 649 NA NA NA NA NA NA 15236 XR_003828067.2 0 32 24 22 30 NA NA NA NA NA NA 15237 XM_044321598.1 28 14 12 24 14 NA NA NA NA NA NA 15238 XM_029324287.2 54 59 49 59 39 NA NA NA NA NA NA 15239 XM_044313251.1 88 0 0 0 89 Q04637 6.87e-177 Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G 1) (eIF-4G1) (p220) Homo sapiens (Human) behavioral fear response [GO:0001662]; cap-dependent translational initiation [GO:0002191]; cellular macromolecule biosynthetic process [GO:0034645]; cellular response to nutrient levels [GO:0031669]; energy homeostasis [GO:0097009]; lung development [GO:0030324]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of autophagy [GO:0010507]; negative regulation of neuron death [GO:1901215]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; neuron differentiation [GO:0030182]; positive regulation of cell death [GO:0010942]; positive regulation of cell growth [GO:0030307]; positive regulation of eukaryotic translation initiation factor 4F complex assembly [GO:1905537]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of mRNA cap binding [GO:1905612]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of translation in response to endoplasmic reticulum stress [GO:0036493]; regulation of cellular response to stress [GO:0080135]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of polysome binding [GO:1905696]; regulation of presynapse assembly [GO:1905606]; regulation of translational initiation [GO:0006446]; response to ethanol [GO:0045471]; translation [GO:0006412]; translational initiation [GO:0006413] GO:0001662; GO:0002191; GO:0003723; GO:0003729; GO:0003743; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0005844; GO:0006412; GO:0006413; GO:0006446; GO:0008135; GO:0008190; GO:0010494; GO:0010507; GO:0010801; GO:0010942; GO:0016020; GO:0016281; GO:0030182; GO:0030307; GO:0030324; GO:0031369; GO:0031669; GO:0033138; GO:0034645; GO:0035278; GO:0036493; GO:0042802; GO:0045471; GO:0045666; GO:0051247; GO:0060090; GO:0060964; GO:0080135; GO:0097009; GO:0098794; GO:1900087; GO:1901215; GO:1905537; GO:1905606; GO:1905612; GO:1905696 15240 XM_029344020.2 0 804 429 340 227 P28648 1.82e-25 CD63 antigen (Mast cell antigen AD1) (CD antigen CD63) Rattus norvegicus (Rat) cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; endosome to melanosome transport [GO:0035646]; epithelial cell differentiation [GO:0030855]; negative regulation of epithelial cell migration [GO:0010633]; pigment cell differentiation [GO:0050931]; pigment granule maturation [GO:0048757]; pigmentation [GO:0043473]; positive regulation of cell adhesion [GO:0045785]; positive regulation of endocytosis [GO:0045807]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of receptor internalization [GO:0002092]; protein localization [GO:0008104]; protein transport [GO:0015031]; regulation of potassium ion transmembrane transport [GO:1901379]; regulation of vascular endothelial growth factor signaling pathway [GO:1900746] GO:0002092; GO:0005615; GO:0005737; GO:0005764; GO:0005765; GO:0005770; GO:0005886; GO:0007160; GO:0008104; GO:0009986; GO:0010008; GO:0010633; GO:0015031; GO:0016020; GO:0016477; GO:0030855; GO:0031902; GO:0031904; GO:0032585; GO:0032991; GO:0035646; GO:0042470; GO:0043473; GO:0044877; GO:0045785; GO:0045807; GO:0048757; GO:0050931; GO:0070062; GO:0097487; GO:1900746; GO:1901379; GO:2001046 15241 XM_044322863.1 383 231 375 337 417 A0A0R4IXF6 0 Histone acetyltransferase KAT2A (EC 2.3.1.48) (Histone glutaryltransferase KAT2A) (EC 2.3.1.-) (Histone succinyltransferase KAT2A) (EC 2.3.1.-) (Lysine acetyltransferase 2A) Danio rerio (Zebrafish) (Brachydanio rerio) bone morphogenesis [GO:0060349]; chromatin remodeling [GO:0006338]; heart development [GO:0007507]; histone H3 acetylation [GO:0043966]; histone H3-K14 acetylation [GO:0044154]; histone succinylation [GO:0106077]; internal peptidyl-lysine acetylation [GO:0018393]; limb development [GO:0060173]; long-term memory [GO:0007616]; peptidyl-lysine glutarylation [GO:0106227]; positive regulation of cytokine production [GO:0001819]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of bone development [GO:1903010]; regulation of cartilage development [GO:0061035]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of synaptic plasticity [GO:0048167]; regulation of T cell activation [GO:0050863] GO:0000123; GO:0001819; GO:0003682; GO:0003713; GO:0004402; GO:0005634; GO:0005737; GO:0005813; GO:0006338; GO:0007507; GO:0007616; GO:0010484; GO:0018393; GO:0043966; GO:0043992; GO:0044154; GO:0045589; GO:0045893; GO:0045944; GO:0048167; GO:0050863; GO:0060173; GO:0060349; GO:0061035; GO:0061733; GO:0106077; GO:0106078; GO:0106227; GO:0106229; GO:0140672; GO:1903010 15242 XM_044325304.1 14 7 9 231 177 Q27084 7.8e-81 Tachylectin-2 (Lectin L10c) Tachypleus tridentatus (Japanese horseshoe crab) innate immune response [GO:0045087] GO:0005576; GO:0030246; GO:0045087 15243 XM_044325304.1 14 7 9 231 177 Q27084 5.6e-66 Tachylectin-2 (Lectin L10c) Tachypleus tridentatus (Japanese horseshoe crab) innate immune response [GO:0045087] GO:0005576; GO:0030246; GO:0045087 15244 XM_029330117.2 174 317 135 795 163 Q14155 3.42e-126 Rho guanine nucleotide exchange factor 7 (Beta-Pix) (COOL-1) (PAK-interacting exchange factor beta) (p85) Homo sapiens (Human) ephrin receptor signaling pathway [GO:0048013]; focal adhesion assembly [GO:0048041]; Golgi organization [GO:0007030]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; negative regulation of microtubule nucleation [GO:1905833]; nervous system development [GO:0007399]; positive regulation of apoptotic process [GO:0043065]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of GTPase activity [GO:0043547]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of GTP binding [GO:1904424]; signal transduction [GO:0007165] GO:0001726; GO:0005085; GO:0005737; GO:0005813; GO:0005829; GO:0005925; GO:0005938; GO:0007030; GO:0007165; GO:0007399; GO:0010763; GO:0019901; GO:0030027; GO:0030032; GO:0032991; GO:0035556; GO:0043005; GO:0043015; GO:0043025; GO:0043065; GO:0043547; GO:0048013; GO:0048041; GO:0097431; GO:0098794; GO:1900026; GO:1904424; GO:1905833; GO:2000394 15245 XM_044329164.1 434 44 0 111 487 NA NA NA NA NA NA 15246 XM_029355994.2 134 58 32 119 123 A9CMA6 6.63e-23 Transmembrane protein 163 (Synaptic vesicle membrane protein of 31 kDa) Rattus norvegicus (Rat) zinc ion import into synaptic vesicle [GO:0099180] GO:0005886; GO:0008270; GO:0016020; GO:0030672; GO:0031901; GO:0097708; GO:0099180 15247 XM_044308120.1 273 401 250 454 553 F1MBP6 4.23e-40 Kelch-like protein 3 Bos taurus (Bovine) distal tubule morphogenesis [GO:0072156]; gene expression [GO:0010467]; ion homeostasis [GO:0050801]; potassium ion homeostasis [GO:0055075]; protein K48-linked ubiquitination [GO:0070936]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; renal sodium ion absorption [GO:0070294]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0003779; GO:0005829; GO:0005856; GO:0006468; GO:0006511; GO:0010467; GO:0016567; GO:0031463; GO:0050801; GO:0055075; GO:0070294; GO:0070936; GO:0072156; GO:0097602 15248 XM_029331005.2 3197 2194 1778 3571 3076 Q9NZN5 1.22e-85 Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF) Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266] GO:0001664; GO:0005085; GO:0005096; GO:0005737; GO:0005829; GO:0007186; GO:0007266; GO:0016020; GO:0051056; GO:0070062 15249 XM_029331005.2 3197 2194 1778 3571 3076 Q9NZN5 2.1e-35 Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF) Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266] GO:0001664; GO:0005085; GO:0005096; GO:0005737; GO:0005829; GO:0007186; GO:0007266; GO:0016020; GO:0051056; GO:0070062 15250 XM_029331005.2 3197 2194 1778 3571 3076 Q9NZN5 3.87e-21 Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF) Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266] GO:0001664; GO:0005085; GO:0005096; GO:0005737; GO:0005829; GO:0007186; GO:0007266; GO:0016020; GO:0051056; GO:0070062 15251 XM_044313598.1 47 19 16 22 24 NA NA NA NA NA NA 15252 XM_029356872.2 8 4 0 0 0 NA NA NA NA NA NA 15253 XM_044318624.1 5 4 6 5 36 O00468 3.22e-23 Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment (C90); Agrin C-terminal 22 kDa fragment (C22)] Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; clustering of voltage-gated sodium channels [GO:0045162]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; neuromuscular junction development [GO:0007528]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of synaptic assembly at neuromuscular junction [GO:0045887]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor clustering [GO:0043113]; signal transduction [GO:0007165]; synapse organization [GO:0050808]; tissue development [GO:0009888] GO:0002162; GO:0005200; GO:0005509; GO:0005576; GO:0005604; GO:0005796; GO:0005886; GO:0007165; GO:0007213; GO:0007528; GO:0009887; GO:0009888; GO:0033691; GO:0035374; GO:0043113; GO:0043202; GO:0043236; GO:0043395; GO:0043547; GO:0045162; GO:0045202; GO:0045887; GO:0045944; GO:0050808; GO:0051491; GO:0062023; GO:0070062 15254 XR_006393733.1 40 14 64 18 130 NA NA NA NA NA NA 15255 XR_006395335.1 163 2 125 24 561 NA NA NA NA NA NA 15256 XM_029347100.2 0 13 26 20 36 NA NA NA NA NA NA 15257 XR_003826321.2 20 0 2 7 4 NA NA NA NA NA NA 15258 XM_029350800.2 0 0 0 0 139 O16025 0 Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (AOS) (EC 4.2.1.-) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)] Plexaura homomalla (Black sea rod) arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; lipid oxidation [GO:0034440]; oxylipin biosynthetic process [GO:0031408] GO:0005506; GO:0005737; GO:0006633; GO:0009978; GO:0016020; GO:0019369; GO:0020037; GO:0031408; GO:0034440; GO:0047677 15259 XM_044309822.1 465 449 125 254 337 NA NA NA NA NA NA 15260 XM_029346384.2 32 5 12 20 80 NA NA NA NA NA NA 15261 XM_044312199.1 721 75 715 108 1677 NA NA NA NA NA NA 15262 XM_044329135.1 126 106 116 64 57 NA NA NA NA NA NA 15263 XM_029332639.2 248717 224283 189499 204178 123130 P26632 4.14e-52 Early growth response protein 1 (EGR-1) (Zinc finger protein Krox-24) Danio rerio (Zebrafish) (Brachydanio rerio) camera-type eye development [GO:0043010]; circadian regulation of gene expression [GO:0032922]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; embryonic viscerocranium morphogenesis [GO:0048703]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005737; GO:0006357; GO:0008270; GO:0010385; GO:0032922; GO:0043010; GO:0043565; GO:0044729; GO:0045893; GO:0045944; GO:0048703; GO:0060059; GO:1990841 15264 XM_044327607.1 0 31 2 0 4 NA NA NA NA NA NA 15265 XM_044323486.1 97 71 187 0 65 B7WFQ1 0 Uncharacterized skeletal organic matrix protein 2 (Uncharacterized SOMP-2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 15266 XM_029358144.2 648 1363 426 674 171 NA NA NA NA NA NA 15267 XM_029324580.2 1569 1903 1190 1945 2401 Q9Z2Z6 1.04e-134 Mitochondrial carnitine/acylcarnitine carrier protein (Carnitine/acylcarnitine translocase) (CAC) (CACT) (mCAC) (Solute carrier family 25 member 20) Mus musculus (Mouse) carnitine transmembrane transport [GO:1902603]; in utero embryonic development [GO:0001701]; lipid transport [GO:0006869]; mitochondrial transport [GO:0006839] GO:0001701; GO:0005739; GO:0005740; GO:0005743; GO:0005829; GO:0006839; GO:0006869; GO:0015227; GO:0022857; GO:1902603 15268 XR_006392060.1 10 0 5 0 3 NA NA NA NA NA NA 15269 XR_006396265.1 2100 23 13 644 13 NA NA NA NA NA NA 15270 XM_044321049.1 0 41 0 0 26 NA NA NA NA NA NA 15271 XM_044310865.1 0 135 187 1 47 NA NA NA NA NA NA 15272 XM_044315383.1 9 15 26 119 98 NA NA NA NA NA NA 15273 XM_029354845.2 385 589 410 453 266 NA NA NA NA NA NA 15274 XM_029346731.2 0 0 0 135 41 NA NA NA NA NA NA 15275 XR_003825038.2 4 0 8 3 3 NA NA NA NA NA NA 15276 XM_029355828.2 1477 735 686 1311 1059 Q5T3U5 0 ATP-binding cassette sub-family C member 10 (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 7) Homo sapiens (Human) leukotriene metabolic process [GO:0006691]; leukotriene transport [GO:0071716]; lipid transport [GO:0006869]; transmembrane transport [GO:0055085] GO:0005524; GO:0005765; GO:0005886; GO:0006691; GO:0006869; GO:0008559; GO:0009925; GO:0015431; GO:0016020; GO:0016323; GO:0016887; GO:0042626; GO:0043225; GO:0055085; GO:0071716; GO:0140359 15277 XM_029334702.2 1846 879 860 1104 2017 Q4G005 0 General transcription and DNA repair factor IIH helicase subunit XPB (TFIIH subunit XPB) (EC 3.6.4.12) (DNA excision repair protein ERCC-3) Rattus norvegicus (Rat) apoptotic process [GO:0006915]; DNA repair [GO:0006281]; DNA topological change [GO:0006265]; embryonic organ development [GO:0048568]; hair cell differentiation [GO:0035315]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; positive regulation of apoptotic process [GO:0043065]; protein localization [GO:0008104]; regulation of mitotic cell cycle phase transition [GO:1901990]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]; response to UV [GO:0009411]; transcription by RNA polymerase II [GO:0006366]; transcription elongation by RNA polymerase I [GO:0006362]; transcription initiation at RNA polymerase II promoter [GO:0006367]; transcription-coupled nucleotide-excision repair [GO:0006283]; UV protection [GO:0009650] GO:0000112; GO:0000439; GO:0000717; GO:0001666; GO:0003677; GO:0005524; GO:0005634; GO:0005669; GO:0005675; GO:0006265; GO:0006281; GO:0006283; GO:0006289; GO:0006362; GO:0006366; GO:0006367; GO:0006915; GO:0006979; GO:0008022; GO:0008104; GO:0009411; GO:0009650; GO:0016887; GO:0033683; GO:0035315; GO:0043065; GO:0043138; GO:0047485; GO:0048568; GO:0097550; GO:1901990; GO:1990841 15278 XM_029330136.2 170 0 187 0 88 Q8VHR5 3.4e-33 Transcriptional repressor p66-beta (GATA zinc finger domain-containing protein 2B) (p66/p68) Mus musculus (Mouse) chromatin remodeling [GO:0006338]; histone deacetylation [GO:0016575]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of cell fate specification [GO:0042659]; regulation of stem cell differentiation [GO:2000736] GO:0000122; GO:0000781; GO:0005634; GO:0005654; GO:0006338; GO:0008270; GO:0016575; GO:0016581; GO:0016607; GO:0042659; GO:0043565; GO:0045892; GO:0045893; GO:2000736 15279 XM_029324825.2 411 499 288 490 389 NA NA NA NA NA NA 15280 XM_044324034.1 95 0 24 107 60 B0R0T1 0 von Willebrand factor A domain-containing protein 8 Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005524; GO:0005737; GO:0005739; GO:0016887 15281 XM_044321036.1 9 0 0 0 30 A2AJ76 1.43e-35 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 15282 XM_044321036.1 9 0 0 0 30 A2AJ76 1.44e-24 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 15283 XM_044321036.1 9 0 0 0 30 A2AJ76 4.62e-24 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 15284 XM_044321036.1 9 0 0 0 30 A2AJ76 5.32e-22 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 15285 XM_044321036.1 9 0 0 0 30 A2AJ76 3.3e-21 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 15286 XM_029347621.2 78 65 413 0 5 NA NA NA NA NA NA 15287 XM_029352306.2 23 52 26 38 24 NA NA NA NA NA NA 15288 XM_044316939.1 74 33 12 23 5 Q4R4S5 3.02e-101 Lysosomal acid lipase/cholesteryl ester hydrolase (Acid cholesteryl ester hydrolase) (LAL) (EC 3.1.1.13) (Cholesteryl esterase) (Lipase A) (Sterol esterase) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) lipid catabolic process [GO:0016042] GO:0004771; GO:0005764; GO:0016042 15289 XR_003825661.2 8 14 1 4 21 NA NA NA NA NA NA 15290 XM_029324136.2 45 14 27 27 123 NA NA NA NA NA NA 15291 XM_044324207.1 72 7 32 81 65 Q8C206 9.56e-26 G-protein coupled receptor 157 Mus musculus (Mouse) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; circadian behavior [GO:0048512]; G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; radial glial cell differentiation [GO:0060019] GO:0004930; GO:0005886; GO:0007166; GO:0007186; GO:0007189; GO:0048512; GO:0051482; GO:0060019; GO:0060170 15292 XR_006392742.1 478 293 4 215 251 NA NA NA NA NA NA 15293 XM_029354925.2 97 158 37 19 269 NA NA NA NA NA NA 15294 XM_044324062.1 7 23 91 64 297 NA NA NA NA NA NA 15295 XM_044307234.1 11 15 10 4 13 Q7M456 7.2e-33 Ribonuclease Oy (RNase Oy) (EC 3.1.27.-) Crassostrea gigas (Pacific oyster) (Crassostrea angulata) NA GO:0003723; GO:0005576; GO:0033897 15296 XM_029346791.2 419 327 314 1 1 NA NA NA NA NA NA 15297 XM_029343169.2 41 3 18 31 4 NA NA NA NA NA NA 15298 XM_029344064.2 712 977 364 707 560 Q9D5E4 0 Dynein regulatory complex subunit 3 (Leucine-rich repeat-containing protein 48) Mus musculus (Mouse) NA GO:0005737; GO:0005929; GO:0005930; GO:0036126 15299 XR_006391364.1 340 71 118 394 230 O94779 1e-30 Contactin-5 (Neural recognition molecule NB-2) (hNB-2) Homo sapiens (Human) axon guidance [GO:0007411]; brain development [GO:0007420]; cell-cell adhesion [GO:0098609]; presynapse assembly [GO:0099054]; sensory perception of sound [GO:0007605] GO:0005576; GO:0005886; GO:0007411; GO:0007420; GO:0007605; GO:0030424; GO:0042734; GO:0098609; GO:0098632; GO:0098982; GO:0099054 15300 XM_029342558.2 561 191 329 614 641 NA NA NA NA NA NA 15301 XM_044308763.1 438 397 435 666 519 Q0KIA2 1.14e-53 PP2C-like domain-containing protein CG9801 Drosophila melanogaster (Fruit fly) NA NA 15302 XR_003823162.2 0 6 0 1 26 NA NA NA NA NA NA 15303 XR_006396417.1 1170 810 668 1060 1150 Q80ZF8 4.83e-34 Adhesion G protein-coupled receptor B3 (Brain-specific angiogenesis inhibitor 3) Mus musculus (Mouse) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; maintenance of synapse structure [GO:0099558]; motor learning [GO:0061743]; myoblast fusion [GO:0007520]; negative regulation of angiogenesis [GO:0016525]; neuron remodeling [GO:0016322]; positive regulation of synapse assembly [GO:0051965]; regulation of dendrite morphogenesis [GO:0048814]; regulation of synapse maturation [GO:0090128]; regulation of synapse pruning [GO:1905806] GO:0004930; GO:0005096; GO:0005886; GO:0007166; GO:0007189; GO:0007520; GO:0016322; GO:0016525; GO:0043083; GO:0048814; GO:0051965; GO:0061743; GO:0090128; GO:0098794; GO:0098839; GO:0099558; GO:0150053; GO:1905806 15304 XR_006396417.1 1170 810 668 1060 1150 Q80ZF8 4.83e-34 Adhesion G protein-coupled receptor B3 (Brain-specific angiogenesis inhibitor 3) Mus musculus (Mouse) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; maintenance of synapse structure [GO:0099558]; motor learning [GO:0061743]; myoblast fusion [GO:0007520]; negative regulation of angiogenesis [GO:0016525]; neuron remodeling [GO:0016322]; positive regulation of synapse assembly [GO:0051965]; regulation of dendrite morphogenesis [GO:0048814]; regulation of synapse maturation [GO:0090128]; regulation of synapse pruning [GO:1905806] GO:0004930; GO:0005096; GO:0005886; GO:0007166; GO:0007189; GO:0007520; GO:0016322; GO:0016525; GO:0043083; GO:0048814; GO:0051965; GO:0061743; GO:0090128; GO:0098794; GO:0098839; GO:0099558; GO:0150053; GO:1905806 15305 XM_029349933.2 21 15 26 28 36 P12276 0 Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Acyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)] Gallus gallus (Chicken) fatty acid biosynthetic process [GO:0006633]; lactate metabolic process [GO:0006089]; positive regulation of appetite [GO:0032100] GO:0003697; GO:0004312; GO:0004313; GO:0004314; GO:0004315; GO:0004316; GO:0004317; GO:0004320; GO:0005737; GO:0006089; GO:0006633; GO:0008659; GO:0008693; GO:0016295; GO:0016296; GO:0031177; GO:0032100; GO:0047117; GO:0047451 15306 XM_029349933.2 21 15 26 28 36 P12276 0 Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Acyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)] Gallus gallus (Chicken) fatty acid biosynthetic process [GO:0006633]; lactate metabolic process [GO:0006089]; positive regulation of appetite [GO:0032100] GO:0003697; GO:0004312; GO:0004313; GO:0004314; GO:0004315; GO:0004316; GO:0004317; GO:0004320; GO:0005737; GO:0006089; GO:0006633; GO:0008659; GO:0008693; GO:0016295; GO:0016296; GO:0031177; GO:0032100; GO:0047117; GO:0047451 15307 XM_029350517.2 69 47 96 78 171 NA NA NA NA NA NA 15308 XR_006395251.1 301 136 250 90 326 NA NA NA NA NA NA 15309 XR_003823486.2 13 38 21 0 0 NA NA NA NA NA NA 15310 XM_029332633.2 0 0 0 0 97 Q99K74 4.93e-85 Mediator of RNA polymerase II transcription subunit 24 (Mediator complex subunit 24) (Thyroid hormone receptor-associated protein 4) (Thyroid hormone receptor-associated protein complex 100 kDa component) (Trap100) (mTRAP100) Mus musculus (Mouse) positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; protein ubiquitination [GO:0016567]; RNA polymerase II preinitiation complex assembly [GO:0051123]; somatic stem cell population maintenance [GO:0035019]; transcription by RNA polymerase II [GO:0006366] GO:0000151; GO:0003712; GO:0003713; GO:0004402; GO:0005634; GO:0005654; GO:0006366; GO:0016567; GO:0016592; GO:0032968; GO:0035019; GO:0044877; GO:0045893; GO:0046966; GO:0051123; GO:0060261; GO:0061630; GO:0070847 15311 XM_029330097.2 18 4 21 5 36 NA NA NA NA NA NA 15312 XR_006391533.1 106 0 10 0 26 NA NA NA NA NA NA 15313 XR_003827853.2 1365 1344 926 1136 698 NA NA NA NA NA NA 15314 XM_029343953.2 83 25 95 58 317 NA NA NA NA NA NA 15315 XM_029358526.2 1042 1050 523 1079 892 Q5R754 4.42e-161 Cyclin-dependent kinase-like 2 (EC 2.7.11.22) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) protein phosphorylation [GO:0006468] GO:0004693; GO:0005524; GO:0005634; GO:0005737; GO:0006468; GO:0106310 15316 XM_029331380.2 0 37 0 0 0 NA NA NA NA NA NA 15317 XM_029332804.2 196 102 102 330 153 NA NA NA NA NA NA 15318 XM_044327692.1 522 160 347 417 803 NA NA NA NA NA NA 15319 XR_006397241.1 52 0 0 0 0 NA NA NA NA NA NA 15320 XM_029347660.2 11 244 66 242 0 NA NA NA NA NA NA 15321 XM_044309769.1 1078 693 543 808 1079 O35594 0 Intraflagellar transport protein 81 homolog (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1) Mus musculus (Mouse) cilium assembly [GO:0060271]; intraciliary anterograde transport [GO:0035720]; intraciliary transport [GO:0042073]; intraciliary transport involved in cilium assembly [GO:0035735]; regulation of smoothened signaling pathway [GO:0008589]; sperm flagellum assembly [GO:0120316]; spermatogenesis [GO:0007283] GO:0005737; GO:0005813; GO:0005814; GO:0005929; GO:0007283; GO:0008589; GO:0015631; GO:0030992; GO:0035720; GO:0035735; GO:0036064; GO:0042073; GO:0060271; GO:0097225; GO:0097228; GO:0120316 15322 XM_044309838.1 0 149 763 374 0 Q29RU2 4.4e-60 Oncoprotein-induced transcript 3 protein Bos taurus (Bovine) NA GO:0005509; GO:0005635 15323 XM_029349398.2 3327 4482 2779 2723 2012 Q5XJK1 9.35e-28 Short coiled-coil protein B Danio rerio (Zebrafish) (Brachydanio rerio) positive regulation of macroautophagy [GO:0016239]; regulation of protein complex stability [GO:0061635] GO:0000139; GO:0005829; GO:0016239; GO:0061635 15324 XM_029332885.2 152 103 56 100 318 O75419 1.22e-171 Cell division control protein 45 homolog (PORC-PI-1) Homo sapiens (Human) DNA replication checkpoint signaling [GO:0000076]; DNA replication initiation [GO:0006270]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via break-induced replication [GO:0000727]; mitotic DNA replication preinitiation complex assembly [GO:1902977] GO:0000076; GO:0000727; GO:0003682; GO:0003688; GO:0003697; GO:0005634; GO:0005654; GO:0005813; GO:0006268; GO:0006270; GO:0031261; GO:0036064; GO:0071162; GO:1902977 15325 XM_044315373.1 11 0 4 8 0 NA NA NA NA NA NA 15326 XM_029358257.2 6 12 161 37 221 NA NA NA NA NA NA 15327 XR_006396772.1 51 444 732 274 193 NA NA NA NA NA NA 15328 XM_044321001.1 249 0 132 0 0 A2ASQ1 5.9e-22 Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment (C90); Agrin C-terminal 22 kDa fragment (C22)] Mus musculus (Mouse) animal organ morphogenesis [GO:0009887]; cell differentiation [GO:0030154]; chemical synaptic transmission [GO:0007268]; motor neuron apoptotic process [GO:0097049]; negative regulation of P-type sodium:potassium-exchanging transporter activity [GO:1903407]; negative regulation of sodium ion export across plasma membrane [GO:1903277]; neuromuscular junction development [GO:0007528]; neurotransmitter receptor metabolic process [GO:0045213]; plasma membrane organization [GO:0007009]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of motor neuron apoptotic process [GO:2000673]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein binding [GO:0032092]; positive regulation of protein geranylgeranylation [GO:2000541]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of synaptic assembly at neuromuscular junction [GO:0045887]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor clustering [GO:0043113]; regulation of axon guidance [GO:1902667]; regulation of cardiac muscle cell membrane potential [GO:0086036]; regulation of cardiac muscle contraction [GO:0055117]; regulation of GTPase activity [GO:0043087]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of protein phosphorylation [GO:0001932]; regulation of synapse organization [GO:0050807]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse assembly [GO:0007416]; tissue development [GO:0009888] GO:0001932; GO:0001934; GO:0002162; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005796; GO:0007009; GO:0007268; GO:0007416; GO:0007528; GO:0009887; GO:0009888; GO:0009986; GO:0030154; GO:0030548; GO:0032092; GO:0033691; GO:0035374; GO:0036122; GO:0042030; GO:0042383; GO:0043083; GO:0043087; GO:0043113; GO:0043395; GO:0043547; GO:0044295; GO:0044325; GO:0045202; GO:0045213; GO:0045887; GO:0045944; GO:0050431; GO:0050731; GO:0050807; GO:0051491; GO:0055117; GO:0061098; GO:0062023; GO:0070507; GO:0071340; GO:0086036; GO:0097049; GO:0098978; GO:1902667; GO:1903277; GO:1903407; GO:2000541; GO:2000673 15329 XM_044310884.1 9 4 6 6 3 NA NA NA NA NA NA 15330 XM_029324079.2 392 518 366 456 384 Q6DGW9 7.76e-87 Calcium load-activated calcium channel (CLAC channel) (GEL complex subunit TMCO1) (Transmembrane and coiled-coil domain-containing protein 1) Danio rerio (Zebrafish) (Brachydanio rerio) calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; endoplasmic reticulum calcium ion homeostasis [GO:0032469]; ER overload response [GO:0006983] GO:0000139; GO:0005262; GO:0005737; GO:0005783; GO:0005789; GO:0006874; GO:0006983; GO:0032469; GO:0043022; GO:0070588 15331 XM_029351505.2 2604 2013 1998 3817 3014 P48999 4.06e-105 Polyunsaturated fatty acid 5-lipoxygenase (EC 1.13.11.-) (Arachidonate 5-lipoxygenase) (5-LO) (5-lipoxygenase) (EC 1.13.11.34) Mus musculus (Mouse) acute inflammatory response [GO:0002526]; arachidonic acid metabolic process [GO:0019369]; dendritic cell migration [GO:0036336]; glucose homeostasis [GO:0042593]; hepoxilin biosynthetic process [GO:0051122]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; leukocyte chemotaxis involved in inflammatory response [GO:0002232]; leukocyte migration involved in inflammatory response [GO:0002523]; leukotriene A4 biosynthetic process [GO:1901753]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; leukotriene production involved in inflammatory response [GO:0002540]; linoleic acid metabolic process [GO:0043651]; lipid oxidation [GO:0034440]; lipoxin biosynthetic process [GO:2001301]; lipoxygenase pathway [GO:0019372]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of inflammatory response [GO:0050728]; negative regulation of response to endoplasmic reticulum stress [GO:1903573]; negative regulation of sprouting angiogenesis [GO:1903671]; negative regulation of vascular wound healing [GO:0061044]; negative regulation of wound healing [GO:0061045]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cytochrome-c oxidase activity [GO:1904960]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of vasoconstriction [GO:0045907]; regulation of cellular response to oxidative stress [GO:1900407]; regulation of cytokine production involved in inflammatory response [GO:1900015]; regulation of fat cell differentiation [GO:0045598]; regulation of inflammatory response [GO:0050727]; regulation of inflammatory response to wounding [GO:0106014]; regulation of insulin secretion [GO:0050796]; regulation of reactive oxygen species biosynthetic process [GO:1903426]; sensory perception of pain [GO:0019233] GO:0001937; GO:0002232; GO:0002523; GO:0002526; GO:0002540; GO:0004051; GO:0004052; GO:0005506; GO:0005634; GO:0005635; GO:0005641; GO:0005654; GO:0005737; GO:0005829; GO:0006691; GO:0006954; GO:0006959; GO:0016363; GO:0016525; GO:0016702; GO:0016787; GO:0019233; GO:0019369; GO:0019370; GO:0019372; GO:0030425; GO:0030501; GO:0031965; GO:0034440; GO:0036336; GO:0036403; GO:0042383; GO:0042593; GO:0043651; GO:0045598; GO:0045907; GO:0048471; GO:0050727; GO:0050728; GO:0050796; GO:0051122; GO:0061044; GO:0061045; GO:0106014; GO:1900015; GO:1900407; GO:1901753; GO:1903426; GO:1903573; GO:1903671; GO:1904960; GO:1904999; GO:2001301 15332 XM_044326107.1 0 0 17 0 9 P04323 3.9e-76 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 15333 XM_044309449.1 2230 1480 676 1458 439 NA NA NA NA NA NA 15334 XM_044313055.1 10 4 17 22 0 O43603 4.8e-21 Galanin receptor type 2 (GAL2-R) (GALR-2) Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell surface receptor signaling pathway [GO:0007166]; feeding behavior [GO:0007631]; galanin-activated signaling pathway [GO:0090663]; inositol phosphate metabolic process [GO:0043647]; learning or memory [GO:0007611]; muscle contraction [GO:0006936]; negative regulation of adenylate cyclase activity [GO:0007194]; neuron projection development [GO:0031175]; neuropeptide signaling pathway [GO:0007218]; phosphatidylinositol metabolic process [GO:0046488]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of large conductance calcium-activated potassium channel activity [GO:1902608]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0004966; GO:0005886; GO:0005929; GO:0006936; GO:0007166; GO:0007188; GO:0007189; GO:0007194; GO:0007200; GO:0007204; GO:0007218; GO:0007611; GO:0007631; GO:0008528; GO:0016020; GO:0017046; GO:0031175; GO:0042923; GO:0043647; GO:0045944; GO:0046488; GO:0090663; GO:1902608 15335 XM_044311261.1 41 17 36 41 19 NA NA NA NA NA NA 15336 XM_029355673.2 51 152 88 25 47 NA NA NA NA NA NA 15337 XM_044322091.1 51 0 70 0 452 Q07494 4.65e-27 Ephrin type-B receptor 1 (EC 2.7.10.1) (EPH-like kinase 6) (EK6) (cEK6) (Tyrosine-protein kinase receptor EPH-2) Gallus gallus (Chicken) axon guidance [GO:0007411]; cell chemotaxis [GO:0060326]; cell-substrate adhesion [GO:0031589]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; ephrin receptor signaling pathway [GO:0048013]; establishment of cell polarity [GO:0030010]; positive regulation of kinase activity [GO:0033674]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0004714; GO:0005005; GO:0005524; GO:0005886; GO:0007169; GO:0007411; GO:0030010; GO:0030425; GO:0031589; GO:0031901; GO:0033674; GO:0043005; GO:0043235; GO:0046328; GO:0046777; GO:0048013; GO:0051965; GO:0060326; GO:0060996; GO:0060997; GO:0070372 15338 XM_044317366.1 1134 1248 0 444 800 Q96AY4 3.94e-115 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15339 XM_044317366.1 1134 1248 0 444 800 Q96AY4 4.08e-114 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15340 XM_044317366.1 1134 1248 0 444 800 Q96AY4 1.15e-113 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15341 XM_044317366.1 1134 1248 0 444 800 Q96AY4 3.47e-84 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15342 XM_044317366.1 1134 1248 0 444 800 Q96AY4 3.38e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15343 XM_029324519.2 193 157 47 131 121 NA NA NA NA NA NA 15344 XM_044317285.1 491 344 268 476 299 Q9CXR1 9.49e-77 Dehydrogenase/reductase SDR family member 7 (EC 1.1.1.-) (Retinal short-chain dehydrogenase/reductase 4) (retSDR4) (Short chain dehydrogenase/reductase family 34C member 1) (Protein SDR34C1) Mus musculus (Mouse) NA GO:0004090; GO:0005789; GO:0016616; GO:0052650 15345 XM_029330103.2 113 101 52 126 192 P20241 2.65e-110 Neuroglian Drosophila melanogaster (Fruit fly) axon ensheathment [GO:0008366]; axon extension [GO:0048675]; axonogenesis [GO:0007409]; cell adhesion involved in heart morphogenesis [GO:0061343]; cell-cell adhesion [GO:0098609]; central complex development [GO:0048036]; dendrite morphogenesis [GO:0048813]; establishment of glial blood-brain barrier [GO:0060857]; female courtship behavior [GO:0008050]; imaginal disc morphogenesis [GO:0007560]; male courtship behavior [GO:0008049]; melanotic encapsulation of foreign target [GO:0035011]; motor neuron axon guidance [GO:0008045]; mushroom body development [GO:0016319]; nerve maturation [GO:0021682]; neuron cell-cell adhesion [GO:0007158]; photoreceptor cell axon guidance [GO:0072499]; regulation of female receptivity [GO:0045924]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]; synapse organization [GO:0050808] GO:0005509; GO:0005886; GO:0005918; GO:0005919; GO:0005923; GO:0007158; GO:0007409; GO:0007560; GO:0008045; GO:0008049; GO:0008050; GO:0008366; GO:0016020; GO:0016319; GO:0019991; GO:0021682; GO:0030175; GO:0030424; GO:0030425; GO:0035011; GO:0035151; GO:0043025; GO:0045924; GO:0048036; GO:0048675; GO:0048813; GO:0050808; GO:0050839; GO:0060857; GO:0061343; GO:0072499; GO:0098609 15346 XR_006398021.1 9 136 136 2 56 NA NA NA NA NA NA 15347 XM_044320336.1 14 14 6 0 11 Q566X8 4.16e-23 Diencephalon/mesencephalon homeobox protein 1-B Danio rerio (Zebrafish) (Brachydanio rerio) midbrain development [GO:0030901]; regulation of cell cycle [GO:0051726]; regulation of mitotic cell cycle [GO:0007346]; regulation of neural retina development [GO:0061074]; regulation of neurogenesis [GO:0050767]; regulation of transcription by RNA polymerase II [GO:0006357]; retina development in camera-type eye [GO:0060041] GO:0000977; GO:0000981; GO:0005634; GO:0006357; GO:0007346; GO:0030901; GO:0050767; GO:0051726; GO:0060041; GO:0061074 15348 XM_029345946.2 320 227 129 173 307 P34144 1.18e-34 Rho-related protein rac1A Dictyostelium discoideum (Social amoeba) actin filament organization [GO:0007015]; cortical cytoskeleton organization [GO:0030865]; engulfment of apoptotic cell [GO:0043652]; establishment or maintenance of cell polarity [GO:0007163]; mitotic cytokinesis [GO:0000281]; positive regulation of actin filament polymerization [GO:0030838]; Rac protein signal transduction [GO:0016601]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of mitotic cytokinesis [GO:1902412] GO:0000281; GO:0001891; GO:0003924; GO:0005525; GO:0005811; GO:0005856; GO:0005886; GO:0005938; GO:0007015; GO:0007163; GO:0008360; GO:0016601; GO:0019901; GO:0030838; GO:0030865; GO:0031254; GO:0031410; GO:0032956; GO:0042995; GO:0043652; GO:0045335; GO:0048471; GO:1902412; GO:1904269; GO:2000145 15349 XM_044315057.1 386 373 204 344 255 Q5QJC4 3.72e-126 DNA cross-link repair 1A protein (Beta-lactamase MBLAC2) (EC 3.5.2.6) (SNM1 homolog A) (chSNM1A) Gallus gallus (Chicken) double-strand break repair via nonhomologous end joining [GO:0006303]; interstrand cross-link repair [GO:0036297]; protection from non-homologous end joining at telomere [GO:0031848] GO:0003684; GO:0005654; GO:0006303; GO:0008800; GO:0031848; GO:0035312; GO:0036297; GO:0046872 15350 XM_029357116.2 1035 599 544 770 896 A6H7I8 2.41e-164 TBC1 domain family member 14 Bos taurus (Bovine) activation of GTPase activity [GO:0090630]; negative regulation of autophagy [GO:0010507]; recycling endosome to Golgi transport [GO:0071955]; regulation of autophagosome assembly [GO:2000785] GO:0005096; GO:0005654; GO:0005776; GO:0005794; GO:0005829; GO:0010507; GO:0019901; GO:0055037; GO:0071955; GO:0090630; GO:2000785 15351 XM_029344033.2 1669 1672 1201 1054 1386 Q9VFC8 0 Glycogen [starch] synthase (EC 2.4.1.11) (Glycogen synthase) Drosophila melanogaster (Fruit fly) cellular response to starvation [GO:0009267]; cellular response to sucrose stimulus [GO:0071329]; glycogen biosynthetic process [GO:0005978]; glycogen metabolic process [GO:0005977]; glycophagy [GO:0061723]; positive regulation of glycogen catabolic process [GO:0045819]; response to sucrose [GO:0009744] GO:0004373; GO:0005737; GO:0005776; GO:0005977; GO:0005978; GO:0009267; GO:0009744; GO:0031410; GO:0045819; GO:0061723; GO:0071329 15352 XM_044321914.1 3388 2147 1315 2513 2819 O94827 1.57e-85 Pleckstrin homology domain-containing family G member 5 (PH domain-containing family G member 5) (Guanine nucleotide exchange factor 720) (GEF720) Homo sapiens (Human) endothelial cell chemotaxis [GO:0035767]; endothelial cell migration [GO:0043542]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266] GO:0005085; GO:0005737; GO:0005829; GO:0005886; GO:0005911; GO:0007266; GO:0030027; GO:0030139; GO:0030424; GO:0035767; GO:0043123; GO:0043542; GO:0048471; GO:0051056 15353 XM_044326382.1 715 381 422 760 1174 P07942 0 Laminin subunit beta-1 (Laminin B1 chain) (Laminin-1 subunit beta) (Laminin-10 subunit beta) (Laminin-12 subunit beta) (Laminin-2 subunit beta) (Laminin-6 subunit beta) (Laminin-8 subunit beta) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; basement membrane assembly [GO:0070831]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; endodermal cell differentiation [GO:0035987]; neuron projection development [GO:0031175]; neuronal-glial interaction involved in cerebral cortex radial glia guided migration [GO:0021812]; odontogenesis [GO:0042476]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of muscle cell differentiation [GO:0051149]; regulation of basement membrane organization [GO:0110011]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888] GO:0005178; GO:0005198; GO:0005201; GO:0005576; GO:0005604; GO:0005606; GO:0005607; GO:0005615; GO:0005788; GO:0007155; GO:0009887; GO:0009888; GO:0016477; GO:0021812; GO:0030335; GO:0031175; GO:0034446; GO:0035987; GO:0042476; GO:0043256; GO:0043257; GO:0043259; GO:0045785; GO:0048471; GO:0050679; GO:0051149; GO:0062023; GO:0070062; GO:0070831; GO:0098637; GO:0110011; GO:2001046 15354 XM_029358732.2 910 878 397 7 564 Q80UJ7 0 Rab3 GTPase-activating protein catalytic subunit (RAB3 GTPase-activating protein 130 kDa subunit) (Rab3-GAP p130) (Rab3-GAP) Mus musculus (Mouse) brain development [GO:0007420]; camera-type eye development [GO:0043010]; establishment of protein localization to endoplasmic reticulum membrane [GO:0097051]; excitatory postsynaptic potential [GO:0060079]; face morphogenesis [GO:0060325]; hypothalamus development [GO:0021854]; lipid droplet organization [GO:0034389]; positive regulation of autophagosome assembly [GO:2000786]; positive regulation of endoplasmic reticulum tubular network organization [GO:1903373]; positive regulation of gene expression [GO:0010628]; positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization [GO:0061646]; positive regulation of GTPase activity [GO:0043547]; positive regulation of protein lipidation [GO:1903061]; protein stabilization [GO:0050821]; regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903233]; regulation of GTPase activity [GO:0043087]; regulation of Rab protein signal transduction [GO:0032483]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic vesicle priming [GO:0010807]; synaptic vesicle transport [GO:0048489] GO:0005085; GO:0005096; GO:0005737; GO:0005794; GO:0005811; GO:0007420; GO:0010628; GO:0010807; GO:0021854; GO:0031267; GO:0032483; GO:0032991; GO:0034389; GO:0043010; GO:0043087; GO:0043547; GO:0048172; GO:0048489; GO:0050821; GO:0060076; GO:0060079; GO:0060325; GO:0061646; GO:0071782; GO:0097051; GO:0098794; GO:1903061; GO:1903233; GO:1903373; GO:2000786 15355 XM_029358732.2 910 878 397 7 564 Q80UJ7 4.67e-54 Rab3 GTPase-activating protein catalytic subunit (RAB3 GTPase-activating protein 130 kDa subunit) (Rab3-GAP p130) (Rab3-GAP) Mus musculus (Mouse) brain development [GO:0007420]; camera-type eye development [GO:0043010]; establishment of protein localization to endoplasmic reticulum membrane [GO:0097051]; excitatory postsynaptic potential [GO:0060079]; face morphogenesis [GO:0060325]; hypothalamus development [GO:0021854]; lipid droplet organization [GO:0034389]; positive regulation of autophagosome assembly [GO:2000786]; positive regulation of endoplasmic reticulum tubular network organization [GO:1903373]; positive regulation of gene expression [GO:0010628]; positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization [GO:0061646]; positive regulation of GTPase activity [GO:0043547]; positive regulation of protein lipidation [GO:1903061]; protein stabilization [GO:0050821]; regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903233]; regulation of GTPase activity [GO:0043087]; regulation of Rab protein signal transduction [GO:0032483]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic vesicle priming [GO:0010807]; synaptic vesicle transport [GO:0048489] GO:0005085; GO:0005096; GO:0005737; GO:0005794; GO:0005811; GO:0007420; GO:0010628; GO:0010807; GO:0021854; GO:0031267; GO:0032483; GO:0032991; GO:0034389; GO:0043010; GO:0043087; GO:0043547; GO:0048172; GO:0048489; GO:0050821; GO:0060076; GO:0060079; GO:0060325; GO:0061646; GO:0071782; GO:0097051; GO:0098794; GO:1903061; GO:1903233; GO:1903373; GO:2000786 15356 XR_006394716.1 275 1434 496 114 185 NA NA NA NA NA NA 15357 XM_044308837.1 64 27 9 95 1 Q4R5Y0 3.32e-35 Uncharacterized protein CFAP68 (cilia and flagella associated protein 68) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0005634 15358 XR_006396122.1 10 1 0 0 0 NA NA NA NA NA NA 15359 XM_044322171.1 962 577 426 1066 767 A8JF70 6.7e-56 Outer dynein arm protein 1 (Docking complex component 2) Chlamydomonas reinhardtii (Chlamydomonas smithii) cilium movement involved in cell motility [GO:0060294]; outer dynein arm assembly [GO:0036158] GO:0036157; GO:0036158; GO:0060294 15360 XR_006394744.1 706 1034 285 562 378 NA NA NA NA NA NA 15361 XM_044316663.1 13 0 0 0 0 NA NA NA NA NA NA 15362 XM_029338628.2 202 66 142 0 47 NA NA NA NA NA NA 15363 XM_044320829.1 87 98 79 76 80 NA NA NA NA NA NA 15364 XM_029340177.2 605 194 293 360 323 Q6PJI9 0 GATOR complex protein WDR59 (WD repeat-containing protein 59) Homo sapiens (Human) cellular response to amino acid starvation [GO:0034198]; negative regulation of TORC1 signaling [GO:1904262]; positive regulation of TOR signaling [GO:0032008]; positive regulation of TORC1 signaling [GO:1904263] GO:0005765; GO:0005774; GO:0032008; GO:0034198; GO:0035591; GO:0035859; GO:0061700; GO:1904262; GO:1904263 15365 XM_029344759.2 899 661 644 692 639 NA NA NA NA NA NA 15366 XM_044326888.1 100 8 123 8 121 NA NA NA NA NA NA 15367 XR_003824026.2 70 57 39 109 78 NA NA NA NA NA NA 15368 XM_044315771.1 20 0 15 0 3 NA NA NA NA NA NA 15369 XM_044317350.1 75 516 331 684 1231 NA NA NA NA NA NA 15370 XM_029358280.2 0 99 0 102 0 Q21279 1.64e-101 Probable tubulin polyglutamylase ttll-15 (EC 6.-.-.-) (Tubulin--tyrosine ligase-like protein 15) Caenorhabditis elegans oviposition [GO:0018991]; protein modification process [GO:0036211] GO:0005524; GO:0016874; GO:0018991; GO:0036211 15371 XM_044309271.1 5 11 3 26 5 NA NA NA NA NA NA 15372 XM_029345397.2 2861 2366 1651 1922 1147 Q8CAI1 4.02e-24 Coiled-coil domain-containing protein 142 Mus musculus (Mouse) NA NA 15373 XM_029332607.2 393 205 142 333 101 O95671 8.5e-67 Probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein [Includes: dTTP/UTP pyrophosphatase (dTTPase/UTPase) (EC 3.6.1.9) (Nucleoside triphosphate pyrophosphatase) (Nucleotide pyrophosphatase) (Nucleotide PPase); N-acetylserotonin O-methyltransferase-like protein (ASMTL) (EC 2.1.1.-)] Homo sapiens (Human) methylation [GO:0032259]; nucleotide metabolic process [GO:0009117] GO:0005829; GO:0008171; GO:0009117; GO:0032259; GO:0036218; GO:0036221; GO:0047429 15374 XM_044317758.1 66 52 44 89 132 NA NA NA NA NA NA 15375 XM_029335368.2 1674 2420 1282 1956 1405 Q6PBN2 2.06e-84 Axin interactor, dorsalization-associated protein (Axin interaction partner and dorsalization antagonist) Danio rerio (Zebrafish) (Brachydanio rerio) determination of ventral identity [GO:0048264]; dorsal/ventral pattern formation [GO:0009953]; negative regulation of determination of dorsal identity [GO:2000016]; negative regulation of JNK cascade [GO:0046329]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of protein-containing complex assembly [GO:0031333] GO:0009953; GO:0016020; GO:0031333; GO:0035091; GO:0043508; GO:0046329; GO:0048264; GO:2000016 15376 XM_044328030.1 477 259 218 457 454 O97902 0 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein) (ADP-ribosylation factor-directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (DEF-1) (Differentiation-enhancing factor 1) (PIP2-dependent ARF1 GAP) Bos taurus (Bovine) cilium assembly [GO:0060271]; positive regulation of GTPase activity [GO:0043547]; positive regulation of membrane tubulation [GO:1903527] GO:0002102; GO:0005096; GO:0005737; GO:0016020; GO:0043547; GO:0046872; GO:0060271; GO:1903527 15377 XM_044321420.1 54 17 28 12 55 Q91ZI0 1.22e-64 Cadherin EGF LAG seven-pass G-type receptor 3 Mus musculus (Mouse) axonal fasciculation [GO:0007413]; cell-cell adhesion [GO:0098609]; cilium assembly [GO:0060271]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; planar cell polarity pathway involved in axon guidance [GO:1904938]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] GO:0001932; GO:0004930; GO:0005509; GO:0005886; GO:0007156; GO:0007413; GO:0032880; GO:0036514; GO:0036515; GO:0060271; GO:0097475; GO:0098609; GO:1904938 15378 XM_044321420.1 54 17 28 12 55 Q91ZI0 6.05e-45 Cadherin EGF LAG seven-pass G-type receptor 3 Mus musculus (Mouse) axonal fasciculation [GO:0007413]; cell-cell adhesion [GO:0098609]; cilium assembly [GO:0060271]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; planar cell polarity pathway involved in axon guidance [GO:1904938]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] GO:0001932; GO:0004930; GO:0005509; GO:0005886; GO:0007156; GO:0007413; GO:0032880; GO:0036514; GO:0036515; GO:0060271; GO:0097475; GO:0098609; GO:1904938 15379 XM_044321420.1 54 17 28 12 55 Q91ZI0 1.41e-37 Cadherin EGF LAG seven-pass G-type receptor 3 Mus musculus (Mouse) axonal fasciculation [GO:0007413]; cell-cell adhesion [GO:0098609]; cilium assembly [GO:0060271]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; planar cell polarity pathway involved in axon guidance [GO:1904938]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] GO:0001932; GO:0004930; GO:0005509; GO:0005886; GO:0007156; GO:0007413; GO:0032880; GO:0036514; GO:0036515; GO:0060271; GO:0097475; GO:0098609; GO:1904938 15380 XM_044321420.1 54 17 28 12 55 Q91ZI0 8.91e-33 Cadherin EGF LAG seven-pass G-type receptor 3 Mus musculus (Mouse) axonal fasciculation [GO:0007413]; cell-cell adhesion [GO:0098609]; cilium assembly [GO:0060271]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; planar cell polarity pathway involved in axon guidance [GO:1904938]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] GO:0001932; GO:0004930; GO:0005509; GO:0005886; GO:0007156; GO:0007413; GO:0032880; GO:0036514; GO:0036515; GO:0060271; GO:0097475; GO:0098609; GO:1904938 15381 XR_006395487.1 14 2 0 0 0 NA NA NA NA NA NA 15382 XM_029338602.2 576 470 216 332 250 Q925C0 4.6e-48 Synaptotagmin-9 (Synaptotagmin 5) (Synaptotagmin IX) (SytIX) (Synaptotagmin V) Rattus norvegicus (Rat) calcium-dependent activation of synaptic vesicle fusion [GO:0099502]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; detection of calcium ion [GO:0005513]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of insulin secretion [GO:0050796]; vesicle-mediated transport [GO:0016192] GO:0000149; GO:0001786; GO:0005509; GO:0005513; GO:0005544; GO:0005546; GO:0005886; GO:0014059; GO:0016192; GO:0017156; GO:0017158; GO:0019905; GO:0030141; GO:0030276; GO:0030667; GO:0030672; GO:0031045; GO:0042802; GO:0045956; GO:0050796; GO:0070382; GO:0071277; GO:0098686; GO:0099502 15383 XM_029334036.2 808 1168 499 458 475 Q7ZT47 3.32e-84 DNA replication complex GINS protein PSF1 (GINS complex subunit 1) Xenopus laevis (African clawed frog) DNA replication [GO:0006260] GO:0000811; GO:0003682; GO:0006260; GO:0071162 15384 XM_044321226.1 189 156 11 186 150 Q969U6 5.72e-36 F-box/WD repeat-containing protein 5 (F-box and WD-40 domain-containing protein 5) Homo sapiens (Human) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of centrosome duplication [GO:0010824]; regulation of mitotic nuclear division [GO:0007088]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0005737; GO:0005829; GO:0007088; GO:0010824; GO:0016567; GO:0019005; GO:0019901; GO:0031146; GO:0043161; GO:0080008 15385 XM_044321226.1 189 156 11 186 150 Q969U6 6.43e-34 F-box/WD repeat-containing protein 5 (F-box and WD-40 domain-containing protein 5) Homo sapiens (Human) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of centrosome duplication [GO:0010824]; regulation of mitotic nuclear division [GO:0007088]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0005737; GO:0005829; GO:0007088; GO:0010824; GO:0016567; GO:0019005; GO:0019901; GO:0031146; GO:0043161; GO:0080008 15386 XM_029348583.2 0 0 0 7 3 Q7LHG5 4.67e-60 Transposon Ty3-I Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-2 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p52 (IN); Integrase p49 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 15387 XM_029330363.2 1027 628 636 850 818 Q60525 2.09e-123 Telomerase Cajal body protein 1 (Guanine nucleotide-binding protein beta 5) (WD repeat-containing protein 79) (WD40 repeat-containing protein antisense to TP53 gene homolog) Mesocricetus auratus (Golden hamster) Cajal body organization [GO:0030576]; DNA repair [GO:0006281]; positive regulation of DNA repair [GO:0045739]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; positive regulation of establishment of protein localization to telomere [GO:1904851]; positive regulation of telomerase activity [GO:0051973]; protein localization to Cajal body [GO:1904867]; RNA folding [GO:0034337]; scaRNA localization to Cajal body [GO:0090666]; telomerase RNA localization to Cajal body [GO:0090671]; telomere formation via telomerase [GO:0032203]; telomere maintenance via telomerase [GO:0007004] GO:0000781; GO:0003723; GO:0005697; GO:0005829; GO:0006281; GO:0007004; GO:0015030; GO:0030576; GO:0031625; GO:0032203; GO:0034337; GO:0035861; GO:0042393; GO:0042802; GO:0044877; GO:0045739; GO:0051087; GO:0051973; GO:0070034; GO:0090666; GO:0090671; GO:1904851; GO:1904867; GO:1905168; GO:2000781; GO:2001034 15388 XM_029342099.2 124 49 46 18 131 NA NA NA NA NA NA 15389 XM_029354013.2 43 31 8 23 22 Q9CYL5 4.2e-23 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Mus musculus (Mouse) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070374 15390 XM_029334764.2 6589 4693 3853 8731 7376 Q761V0 7.84e-175 Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5) Mus musculus (Mouse) glycine import across plasma membrane [GO:1903804]; glycine transport [GO:0015816]; neurotransmitter reuptake [GO:0098810]; neurotransmitter uptake [GO:0001504]; sodium ion transmembrane transport [GO:0035725]; synaptic transmission, glycinergic [GO:0060012] GO:0001504; GO:0005768; GO:0005886; GO:0015187; GO:0015375; GO:0015816; GO:0031045; GO:0035725; GO:0042734; GO:0046872; GO:0060012; GO:0098690; GO:0098810; GO:1903804 15391 XM_044316454.1 149 0 186 51 286 NA NA NA NA NA NA 15392 XM_044316866.1 23 7 16 0 30 NA NA NA NA NA NA 15393 XR_006396744.1 42 9 35 11 56 NA NA NA NA NA NA 15394 XM_029343125.2 1013 252 705 914 1706 Q61824 1.15e-128 Disintegrin and metalloproteinase domain-containing protein 12 (ADAM 12) (EC 3.4.24.-) (Meltrin-alpha) Mus musculus (Mouse) cell adhesion [GO:0007155]; positive regulation of angiogenesis [GO:0045766]; proteolysis [GO:0006508] GO:0004222; GO:0005654; GO:0005886; GO:0006508; GO:0007155; GO:0017124; GO:0045766; GO:0046872 15395 XM_044318981.1 0 0 0 11 0 P70196 2.84e-108 TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6) Mus musculus (Mouse) activation of NF-kappaB-inducing kinase activity [GO:0007250]; activation of protein kinase activity [GO:0032147]; animal organ morphogenesis [GO:0009887]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; bone remodeling [GO:0046849]; bone resorption [GO:0045453]; cell development [GO:0048468]; cellular response to cytokine stimulus [GO:0071345]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-17-mediated signaling pathway [GO:0097400]; JNK cascade [GO:0007254]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin production [GO:0002637]; response to interleukin-1 [GO:0070555]; signal transduction [GO:0007165]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000122; GO:0000209; GO:0001503; GO:0001701; GO:0001843; GO:0002637; GO:0002726; GO:0004842; GO:0005164; GO:0005634; GO:0005737; GO:0005811; GO:0005829; GO:0005886; GO:0005938; GO:0006955; GO:0006974; GO:0007165; GO:0007249; GO:0007250; GO:0007254; GO:0008270; GO:0009887; GO:0009898; GO:0016567; GO:0019221; GO:0019886; GO:0019901; GO:0030316; GO:0031435; GO:0031624; GO:0031625; GO:0031663; GO:0031666; GO:0031996; GO:0032147; GO:0032735; GO:0032743; GO:0032755; GO:0032813; GO:0032991; GO:0033209; GO:0035631; GO:0042088; GO:0042102; GO:0042475; GO:0042802; GO:0042826; GO:0042981; GO:0043011; GO:0043122; GO:0043123; GO:0043422; GO:0043507; GO:0045453; GO:0045672; GO:0045892; GO:0045944; GO:0046330; GO:0046849; GO:0047485; GO:0048468; GO:0048471; GO:0048661; GO:0050852; GO:0051091; GO:0051092; GO:0051865; GO:0061630; GO:0070498; GO:0070534; GO:0070555; GO:0071222; GO:0071345; GO:0097400; GO:1901224; GO:1904996; GO:2000679 15396 XR_006391829.1 81 158 74 96 188 NA NA NA NA NA NA 15397 XM_029329418.2 4772 3389 2087 3479 3453 Q5PYH7 0 Disks large homolog 2 (Postsynaptic density protein 93) (PSD-93) Danio rerio (Zebrafish) (Brachydanio rerio) cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; synapse organization [GO:0050808] GO:0007268; GO:0016323; GO:0030054; GO:0030424; GO:0031594; GO:0043005; GO:0043113; GO:0043204; GO:0045197; GO:0050808; GO:0097120; GO:0098609; GO:0098839 15398 XR_006392349.1 16 10 79 39 41 NA NA NA NA NA NA 15399 XM_029350510.2 889 321 150 699 688 NA NA NA NA NA NA 15400 XM_044329218.1 0 0 0 0 34 NA NA NA NA NA NA 15401 XM_029343932.2 0 14 111 16 143 NA NA NA NA NA NA 15402 XM_029338017.2 1331 1138 607 1057 1325 P41565 2.4e-133 Isocitrate dehydrogenase [NAD] subunit gamma 1, mitochondrial (Isocitric dehydrogenase subunit gamma) (NAD(+)-specific ICDH subunit gamma) Rattus norvegicus (Rat) 2-oxoglutarate metabolic process [GO:0006103]; isocitrate metabolic process [GO:0006102]; NADH metabolic process [GO:0006734]; negative regulation of growth [GO:0045926]; tricarboxylic acid cycle [GO:0006099] GO:0000287; GO:0004449; GO:0005524; GO:0005739; GO:0005962; GO:0006099; GO:0006102; GO:0006103; GO:0006734; GO:0045926; GO:0051287 15403 XM_029329737.2 406 281 178 373 351 Q9VY28 1.77e-32 Probable 28S ribosomal protein S25, mitochondrial (MRP-S25) (S25mt) Drosophila melanogaster (Fruit fly) mitochondrial translation [GO:0032543] GO:0003735; GO:0005739; GO:0005763; GO:0032543 15404 XM_029347289.2 152 22 39 166 53 NA NA NA NA NA NA 15405 XM_029356317.2 508 502 297 644 366 Q2KHY7 2.46e-40 Tetratricopeptide repeat protein 23 (TPR repeat protein 23) Bos taurus (Bovine) positive regulation of smoothened signaling pathway [GO:0045880] GO:0005929; GO:0045880 15406 XM_029338052.2 61 0 0 0 0 Q91WC1 1.58e-41 Protection of telomeres protein 1 (mPot1) (POT1-like telomere end-binding protein) Mus musculus (Mouse) chromosome organization [GO:0051276]; DNA duplex unwinding [GO:0032508]; establishment of protein localization to telomere [GO:0070200]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; positive regulation of DNA helicase activity [GO:1905776]; positive regulation of DNA strand elongation [GO:0060383]; positive regulation of helicase activity [GO:0051096]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere maintenance [GO:0032206]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of DNA helicase activity [GO:1905774]; regulation of double-strand break repair via nonhomologous end joining [GO:2001032]; regulation of telomere maintenance via telomerase [GO:0032210]; telomere assembly [GO:0032202]; telomere capping [GO:0016233]; telomere maintenance via telomerase [GO:0007004]; telomeric D-loop disassembly [GO:0061820] GO:0000781; GO:0000783; GO:0005654; GO:0007004; GO:0010521; GO:0016233; GO:0017151; GO:0032202; GO:0032206; GO:0032210; GO:0032211; GO:0032212; GO:0032508; GO:0042162; GO:0043047; GO:0051096; GO:0051276; GO:0051973; GO:0051974; GO:0060383; GO:0061820; GO:0061821; GO:0070187; GO:0070200; GO:0098505; GO:1905773; GO:1905774; GO:1905776; GO:1990955; GO:2001032 15407 XM_029354871.2 6 19 9 2 31 NA NA NA NA NA NA 15408 XM_029323976.2 0 0 342 0 487 Q9JK72 2.09e-99 Copper chaperone for superoxide dismutase (Superoxide dismutase copper chaperone) Rattus norvegicus (Rat) positive regulation of oxidoreductase activity [GO:0051353]; removal of superoxide radicals [GO:0019430] GO:0005507; GO:0005634; GO:0005737; GO:0016532; GO:0019430; GO:0019899; GO:0051353 15409 XM_029351438.2 1486 953 884 1475 1063 Q8C0V0 0 Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (Tousled-like kinase 1) Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; chromosome segregation [GO:0007059]; intracellular protein transport [GO:0006886]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; protein phosphorylation [GO:0006468]; regulation of chromatin organization [GO:1902275] GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0006325; GO:0006468; GO:0006886; GO:0006974; GO:0007059; GO:0018105; GO:0035556; GO:0106310; GO:1902275 15410 XM_029357779.2 68 75 6 67 2 NA NA NA NA NA NA 15411 XR_006393429.1 19 4 4 8 15 NA NA NA NA NA NA 15412 XM_029357494.2 151 62 98 99 140 Q5U374 1.71e-89 Kelch-like protein 12 Danio rerio (Zebrafish) (Brachydanio rerio) anterior/posterior pattern specification [GO:0009952]; convergent extension involved in axis elongation [GO:0060028]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; protein monoubiquitination [GO:0006513]; Wnt signaling pathway [GO:0016055] GO:0006513; GO:0006888; GO:0009952; GO:0014029; GO:0014032; GO:0016055; GO:0030127; GO:0030134; GO:0031463; GO:0048208; GO:0060028 15413 XR_006393718.1 0 2 4 0 17 NA NA NA NA NA NA 15414 XM_044319236.1 0 530 0 0 0 NA NA NA NA NA NA 15415 XM_029340210.2 1 0 2 13 44 NA NA NA NA NA NA 15416 XM_044309014.1 0 0 0 0 7 NA NA NA NA NA NA 15417 XM_044326613.1 3212 4109 1881 2520 2328 P21266 3.2e-81 Glutathione S-transferase Mu 3 (EC 2.5.1.18) (GST class-mu 3) (GSTM3-3) (hGSTM3-3) Homo sapiens (Human) cellular detoxification of nitrogen compound [GO:0070458]; establishment of blood-nerve barrier [GO:0008065]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; response to estrogen [GO:0043627]; xenobiotic catabolic process [GO:0042178] GO:0004364; GO:0005634; GO:0005737; GO:0005829; GO:0006749; GO:0008065; GO:0018916; GO:0019899; GO:0035686; GO:0042178; GO:0042802; GO:0042803; GO:0043295; GO:0043627; GO:0045171; GO:0070062; GO:0070458 15418 XM_029339224.2 108 275 127 523 287 NA NA NA NA NA NA 15419 XM_029343047.2 992 571 401 519 553 Q9SK39 1.41e-27 Probable steroid-binding protein 3 (AtMP3) (Membrane-associated progesterone-binding protein 2) (AtMAPR2) Arabidopsis thaliana (Mouse-ear cress) NA GO:0005496; GO:0005634; GO:0005773; GO:0005829; GO:0012505; GO:0016020 15420 XM_044324898.1 208 119 96 144 185 Q3T1G7 0 Conserved oligomeric Golgi complex subunit 7 (COG complex subunit 7) (Component of oligomeric Golgi complex 7) Rattus norvegicus (Rat) glycosylation [GO:0070085]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886]; protein glycosylation [GO:0006486]; protein localization to Golgi apparatus [GO:0034067]; protein localization to organelle [GO:0033365]; protein stabilization [GO:0050821]; retrograde transport, vesicle recycling within Golgi [GO:0000301]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] GO:0000139; GO:0000301; GO:0005730; GO:0006486; GO:0006886; GO:0006890; GO:0007030; GO:0017119; GO:0033365; GO:0034067; GO:0050821; GO:0070085 15421 XM_029324943.2 9 0 5 1 16 NA NA NA NA NA NA 15422 XR_006392305.1 20 27 0 6 14 NA NA NA NA NA NA 15423 XM_029351231.2 13 46 19 46 44 C0H692 3.25e-47 Small cysteine-rich protein 3 (Amil-SCRiP3) (SCRiP3) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0042151; GO:0090729 15424 XM_044309337.1 21 14 4 19 41 NA NA NA NA NA NA 15425 XM_044322322.1 8 0 13 0 19 NA NA NA NA NA NA 15426 XM_044312460.1 940 0 479 0 0 NA NA NA NA NA NA 15427 XM_044320575.1 65 7 0 0 29 NA NA NA NA NA NA 15428 XR_006397424.1 0 12 14 35 0 NA NA NA NA NA NA 15429 XM_029340624.2 861 669 386 337 331 Q7Z5V6 2.53e-68 Protein phosphatase 1 regulatory subunit 32 Homo sapiens (Human) NA GO:0005737; GO:0019902; GO:0036064 15430 XR_003827401.2 53 37 245 31 240 NA NA NA NA NA NA 15431 XM_029352881.2 0 107 0 0 182 P46869 3.42e-59 Kinesin-like protein FLA10 (Protein KHP1) Chlamydomonas reinhardtii (Chlamydomonas smithii) intraciliary anterograde transport [GO:0035720]; motile cilium assembly [GO:0044458] GO:0003777; GO:0005524; GO:0005874; GO:0005929; GO:0008017; GO:0031514; GO:0035720; GO:0036064; GO:0044458; GO:0097014 15432 XM_044328052.1 264 5201 134 760 3561 NA NA NA NA NA NA 15433 XM_044320280.1 1106 483 503 1520 1591 Q91821 0 Maternal embryonic leucine zipper kinase (MELK) (EC 2.7.11.1) (Protein kinase Eg3) (pEg3 kinase) Xenopus laevis (African clawed frog) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell population proliferation [GO:0008283]; hemopoiesis [GO:0030097]; neural precursor cell proliferation [GO:0061351]; positive regulation of apoptotic process [GO:0043065]; protein autophosphorylation [GO:0046777] GO:0004674; GO:0004715; GO:0005509; GO:0005524; GO:0005886; GO:0005938; GO:0006915; GO:0007049; GO:0008283; GO:0008289; GO:0030097; GO:0043065; GO:0046777; GO:0061351; GO:0106310 15434 XM_029358458.2 0 0 0 36 148 P54131 2.93e-66 Neuronal acetylcholine receptor subunit alpha-7 Bos taurus (Bovine) calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; cognition [GO:0050890]; ion transmembrane transport [GO:0034220]; negative regulation of tumor necrosis factor production [GO:0032720]; nervous system process [GO:0050877]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAPK cascade [GO:0043410]; regulation of membrane potential [GO:0042391]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271] GO:0001540; GO:0001666; GO:0005231; GO:0005886; GO:0005892; GO:0006816; GO:0006874; GO:0007165; GO:0007268; GO:0007271; GO:0008284; GO:0015464; GO:0015643; GO:0017081; GO:0022848; GO:0030594; GO:0032720; GO:0034220; GO:0035094; GO:0042166; GO:0042391; GO:0042803; GO:0043005; GO:0043410; GO:0045202; GO:0045211; GO:0045766; GO:0050877; GO:0050890; GO:1904315 15435 XM_029348732.2 40 20 7 49 4 NA NA NA NA NA NA 15436 XM_044312250.1 23 0 4 0 0 NA NA NA NA NA NA 15437 XM_044317466.1 132 33 87 71 72 Q5BJQ7 2.62e-69 Transcriptional adapter 1 (Transcriptional adapter 1-like protein) Rattus norvegicus (Rat) histone H3 acetylation [GO:0043966]; monoubiquitinated histone deubiquitination [GO:0035521]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000124; GO:0003713; GO:0005634; GO:0005654; GO:0005829; GO:0005925; GO:0006357; GO:0035521; GO:0035522; GO:0043966 15438 XM_029344364.2 0 0 0 0 336 Q5XJ85 5.99e-27 Myeloid differentiation primary response protein MyD88 Danio rerio (Zebrafish) (Brachydanio rerio) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; monocyte activation [GO:0042117]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; neutrophil activation involved in immune response [GO:0002283]; neutrophil chemotaxis [GO:0030593]; positive regulation of hematopoietic progenitor cell differentiation [GO:1901534]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of hematopoietic progenitor cell differentiation [GO:1901532]; response to molecule of bacterial origin [GO:0002237]; Toll signaling pathway [GO:0008063] GO:0002218; GO:0002237; GO:0002283; GO:0002755; GO:0005737; GO:0005886; GO:0006954; GO:0008063; GO:0030593; GO:0035325; GO:0042117; GO:0042742; GO:0043123; GO:0045087; GO:0050830; GO:0070976; GO:1901532; GO:1901534 15439 XM_029333159.2 57 9 72 35 200 NA NA NA NA NA NA 15440 XM_044323184.1 2165 580 1267 890 631 Q0P4C4 1.36e-68 Dephospho-CoA kinase domain-containing protein Danio rerio (Zebrafish) (Brachydanio rerio) coenzyme A biosynthetic process [GO:0015937] GO:0004140; GO:0005524; GO:0015937 15441 XM_044315944.1 116 91 125 118 151 NA NA NA NA NA NA 15442 XM_029344577.2 1169 915 998 1335 1023 Q5R7E3 1.9e-64 Heme oxygenase 1 (HO-1) (EC 1.14.14.18) [Cleaved into: Heme oxygenase 1 soluble form] Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) apoptotic process [GO:0006915]; heme oxidation [GO:0006788] GO:0004392; GO:0005789; GO:0006788; GO:0006915; GO:0046872 15443 XM_044310537.1 3 4 4 2 19 NA NA NA NA NA NA 15444 XR_006394066.1 47 70 30 19 22 NA NA NA NA NA NA 15445 XM_029343581.2 855 817 117 601 706 Q8R2N1 9.88e-85 Aquaporin-3 (AQP-3) (Aquaglyceroporin-3) Mus musculus (Mouse) cellular response to hypoxia [GO:0071456]; cellular response to oxygen-glucose deprivation [GO:0090650]; establishment of localization in cell [GO:0051649]; glycerol transmembrane transport [GO:0015793]; odontogenesis [GO:0042476]; polyol transmembrane transport [GO:0015791]; positive regulation of immune system process [GO:0002684]; renal water absorption [GO:0070295]; response to retinoic acid [GO:0032526]; urea transport [GO:0015840]; water transport [GO:0006833] GO:0002684; GO:0005654; GO:0005737; GO:0005886; GO:0005911; GO:0006833; GO:0015166; GO:0015204; GO:0015250; GO:0015254; GO:0015791; GO:0015793; GO:0015840; GO:0016323; GO:0032526; GO:0042476; GO:0042802; GO:0051649; GO:0070295; GO:0071456; GO:0090650 15446 XM_029342610.2 59 69 21 77 77 Q9VBW3 3.4e-87 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 15447 XM_044327489.1 43 0 4 3 0 NA NA NA NA NA NA 15448 XM_044328447.1 38 57 9 0 150 NA NA NA NA NA NA 15449 XR_006397153.1 5 3 12 25 31 NA NA NA NA NA NA 15450 XM_029351076.2 20 6 0 15 54 NA NA NA NA NA NA 15451 XM_029349002.2 0 4 19 6 2 NA NA NA NA NA NA 15452 XM_029343572.2 0 30 0 32 49 A0A1L8F5J9 4.59e-57 Glutamate receptor ionotropic, NMDA 1 (GluN1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1) Xenopus laevis (African clawed frog) response to zinc ion [GO:0010043] GO:0004972; GO:0005886; GO:0010043; GO:0017146; GO:0045211; GO:0046872 15453 XR_003827229.2 43 51 43 55 35 NA NA NA NA NA NA 15454 XM_044328359.1 216 0 21 128 71 E1BYJ2 0 DNA mismatch repair protein Msh6 Gallus gallus (Chicken) mismatch repair [GO:0006298]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; negative regulation of DNA endoreduplication [GO:0032876]; positive regulation of B cell proliferation [GO:0030890] GO:0003690; GO:0005524; GO:0005634; GO:0006298; GO:0007095; GO:0030890; GO:0030983; GO:0032301; GO:0032876; GO:0140664 15455 XM_029329889.2 194 152 95 169 153 NA NA NA NA NA NA 15456 XM_029326646.2 18 18 110 39 127 NA NA NA NA NA NA 15457 XM_044316807.1 26 16 0 1 74 NA NA NA NA NA NA 15458 XR_006392482.1 345 447 307 446 497 O00505 1.51e-176 Importin subunit alpha-4 (Importin alpha Q2) (Qip2) (Karyopherin subunit alpha-3) (SRP1-gamma) Homo sapiens (Human) NLS-bearing protein import into nucleus [GO:0006607]; protein import into nucleus [GO:0006606]; protein-containing complex assembly [GO:0065003]; viral entry into host cell [GO:0046718]; viral penetration into host nucleus [GO:0075732] GO:0005634; GO:0005643; GO:0005654; GO:0005829; GO:0006606; GO:0006607; GO:0008022; GO:0008139; GO:0042564; GO:0043657; GO:0046718; GO:0061608; GO:0065003; GO:0075732 15459 XM_029342902.2 2197 2350 1408 1203 1151 Q7ZYZ7 1.47e-71 Polycomb group RING finger protein 1 Danio rerio (Zebrafish) (Brachydanio rerio) aging [GO:0007568]; developmental growth [GO:0048589]; histone H2A-K119 monoubiquitination [GO:0036353]; negative regulation of transcription by RNA polymerase II [GO:0000122] GO:0000122; GO:0007568; GO:0031519; GO:0035102; GO:0036353; GO:0046872; GO:0048589; GO:1990841 15460 XM_029349534.2 0 33 0 0 0 A7SXG9 7.33e-38 Nematocyst expressed protein 8 (NEP-8) (NEP8) Nematostella vectensis (Starlet sea anemone) NA GO:0005576; GO:0042151; GO:0090729 15461 XM_044322399.1 561 476 32 208 200 Q96AY4 5.46e-94 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15462 XM_044322399.1 561 476 32 208 200 Q96AY4 2.25e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15463 XM_044322399.1 561 476 32 208 200 Q96AY4 2.51e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15464 XM_044322399.1 561 476 32 208 200 Q96AY4 2.03e-83 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15465 XM_044322399.1 561 476 32 208 200 Q96AY4 3.87e-83 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15466 XM_044322399.1 561 476 32 208 200 Q96AY4 8.94e-82 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15467 XM_044322399.1 561 476 32 208 200 Q96AY4 1.94e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15468 XR_006391514.1 0 10 1 17 4 NA NA NA NA NA NA 15469 XR_006397476.1 34 24 4 40 32 NA NA NA NA NA NA 15470 XM_029344644.2 65 13 11 54 47 Q6ZSS7 8.16e-43 Major facilitator superfamily domain-containing protein 6 (Macrophage MHC class I receptor 2 homolog) Homo sapiens (Human) antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590] GO:0005886; GO:0016020; GO:0042590 15471 XM_029344644.2 65 13 11 54 47 Q6ZSS7 4.99e-26 Major facilitator superfamily domain-containing protein 6 (Macrophage MHC class I receptor 2 homolog) Homo sapiens (Human) antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590] GO:0005886; GO:0016020; GO:0042590 15472 XM_044309332.1 0 4 13 9 0 NA NA NA NA NA NA 15473 XM_029339766.2 44674 41780 26168 42896 13492 Q4I963 1.65e-27 Cofilin (Actin-depolymerizing factor 1) Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1) (Wheat head blight fungus) (Fusarium graminearum) actin filament depolymerization [GO:0030042]; cell cycle [GO:0007049]; cell division [GO:0051301] GO:0003779; GO:0005737; GO:0007049; GO:0015629; GO:0016363; GO:0030042; GO:0051301 15474 XM_044308055.1 62 0 0 141 143 NA NA NA NA NA NA 15475 XR_006396734.1 0 0 15 0 0 NA NA NA NA NA NA 15476 XM_044311954.1 105 20 13 0 510 NA NA NA NA NA NA 15477 XM_044315098.1 87 426 109 333 483 Q8BH74 0 Nuclear pore complex protein Nup107 (107 kDa nucleoporin) (Nucleoporin Nup107) Mus musculus (Mouse) female gonad development [GO:0008585]; mRNA export from nucleus [GO:0006406]; nephron development [GO:0072006]; nuclear pore complex assembly [GO:0051292]; nucleocytoplasmic transport [GO:0006913]; post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000973]; protein import into nucleus [GO:0006606] GO:0000776; GO:0000973; GO:0005635; GO:0005643; GO:0006406; GO:0006606; GO:0006913; GO:0008585; GO:0017056; GO:0031080; GO:0031965; GO:0034399; GO:0051292; GO:0072006 15478 XM_029333402.2 49 26 4 43 29 O76093 1.68e-29 Fibroblast growth factor 18 (FGF-18) (zFGF5) Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell-cell signaling [GO:0007267]; chondrocyte development [GO:0002063]; endochondral ossification [GO:0001958]; ERK1 and ERK2 cascade [GO:0070371]; fibroblast growth factor receptor signaling pathway [GO:0008543]; intramembranous ossification [GO:0001957]; lung development [GO:0030324]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of cell migration [GO:0030334]; signal transduction [GO:0007165]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] GO:0001525; GO:0001934; GO:0001957; GO:0001958; GO:0002063; GO:0005104; GO:0005105; GO:0005111; GO:0005576; GO:0005615; GO:0005730; GO:0005737; GO:0007165; GO:0007267; GO:0008083; GO:0008283; GO:0008284; GO:0008543; GO:0009653; GO:0009887; GO:0010628; GO:0030154; GO:0030324; GO:0030334; GO:0030949; GO:0032332; GO:0043406; GO:0043536; GO:0045766; GO:0048010; GO:0070371; GO:0070374; GO:2000546 15479 XM_029324164.2 370 245 118 155 218 NA NA NA NA NA NA 15480 XM_029345398.2 1826 1362 878 1381 1182 Q6PF69 0 Major vault protein (MVP) Xenopus laevis (African clawed frog) NA GO:0005634; GO:0005737; GO:1990904 15481 XM_044322429.1 0 0 115 77 129 NA NA NA NA NA NA 15482 XM_029356167.2 0 251 236 0 191 Q9EPE9 0 Endoplasmic reticulum transmembrane helix translocase (EC 7.4.2.-) (Endoplasmic reticulum P5A-ATPase) Mus musculus (Mouse) cellular calcium ion homeostasis [GO:0006874]; extraction of mislocalized protein from ER membrane [GO:0140569]; protein transport [GO:0015031]; transmembrane transport [GO:0055085] GO:0005524; GO:0005789; GO:0006874; GO:0015031; GO:0015662; GO:0016020; GO:0016887; GO:0019829; GO:0046872; GO:0055085; GO:0140567; GO:0140569 15483 XM_029347610.2 847 460 330 624 677 Q95JN5 0 Polyamine-transporting ATPase 13A3 (ATPase family homolog up-regulated in senescence cells 1) (Putrescine transporting ATPase) (EC 7.6.2.16) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0005524; GO:0015594; GO:0016887; GO:0019829; GO:0031901; GO:0031902; GO:0046872; GO:0055038; GO:0140358 15484 XR_006393415.1 577 741 418 680 413 NA NA NA NA NA NA 15485 XM_044314793.1 72 139 677 18 1037 NA NA NA NA NA NA 15486 XM_029347211.2 277 178 167 278 180 A8MT70 2.63e-21 Zinc finger B-box domain-containing protein 1 Homo sapiens (Human) cilium movement [GO:0003341] GO:0003341; GO:0031514; GO:0046872 15487 XM_044324206.1 0 0 17 48 0 Q8C206 6.09e-26 G-protein coupled receptor 157 Mus musculus (Mouse) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; circadian behavior [GO:0048512]; G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; radial glial cell differentiation [GO:0060019] GO:0004930; GO:0005886; GO:0007166; GO:0007186; GO:0007189; GO:0048512; GO:0051482; GO:0060019; GO:0060170 15488 XM_029333732.2 93 0 0 0 0 Q6RT24 1.21e-114 Centromere-associated protein E (Centromere protein E) (CENP-E) (Kinesin superfamily protein 10) (KIF10) (Motor domain of KIF10) Mus musculus (Mouse) attachment of mitotic spindle microtubules to kinetochore [GO:0051315]; attachment of spindle microtubules to kinetochore [GO:0008608]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; establishment of protein localization [GO:0045184]; kinetochore assembly [GO:0051382]; lateral attachment of mitotic spindle microtubules to kinetochore [GO:0099607]; metaphase plate congression [GO:0051310]; microtubule plus-end directed mitotic chromosome migration [GO:0099606]; microtubule-based movement [GO:0007018]; mitotic cell cycle [GO:0000278]; mitotic chromosome movement towards spindle pole [GO:0007079]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly checkpoint signaling [GO:0007094]; mitotic spindle organization [GO:0007052]; positive regulation of attachment of spindle microtubules to kinetochore [GO:0051987]; positive regulation of chromosome segregation [GO:0051984]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; positive regulation of protein kinase activity [GO:0045860]; regulation of developmental process [GO:0050793]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of mitotic nuclear division [GO:0007088]; regulation of protein stability [GO:0031647]; spindle assembly involved in female meiosis I [GO:0007057] GO:0000278; GO:0000775; GO:0000776; GO:0000779; GO:0000940; GO:0003777; GO:0005524; GO:0005634; GO:0005694; GO:0005737; GO:0005828; GO:0005874; GO:0007018; GO:0007052; GO:0007057; GO:0007059; GO:0007079; GO:0007080; GO:0007088; GO:0007094; GO:0008017; GO:0008574; GO:0008608; GO:0015630; GO:0019901; GO:0030071; GO:0030496; GO:0031647; GO:0043231; GO:0043515; GO:0045171; GO:0045184; GO:0045842; GO:0045860; GO:0050793; GO:0051233; GO:0051301; GO:0051310; GO:0051315; GO:0051382; GO:0051984; GO:0051987; GO:0072686; GO:0099606; GO:0099607; GO:1990023 15489 XM_029343105.2 76 91 74 83 138 O34383 2.02e-26 Uncharacterized sodium-dependent transporter YocR Bacillus subtilis (strain 168) NA GO:0005886; GO:0015293 15490 XM_044316194.1 46 53 45 156 90 NA NA NA NA NA NA 15491 XM_044308152.1 96 139 20 85 45 NA NA NA NA NA NA 15492 XM_029343271.2 390 112 104 263 226 Q503Z8 1.48e-43 NA NA NA NA 15493 XM_029330817.2 0 0 0 0 19 A5D6U8 5.25e-77 Acid phosphatase type 7 (EC 3.1.3.2) (Purple acid phosphatase long form) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0003993; GO:0005576; GO:0046872 15494 XM_029344822.2 230 176 124 126 115 Q8C172 5.81e-76 Ceramide synthase 6 (CerS6) (EC 2.3.1.-) (LAG1 longevity assurance homolog 6) (Sphingoid base N-palmitoyltransferase CERS6) (EC 2.3.1.291) Mus musculus (Mouse) ceramide biosynthetic process [GO:0046513]; inflammatory response [GO:0006954]; sphingolipid biosynthetic process [GO:0030148] GO:0003677; GO:0005783; GO:0005789; GO:0006954; GO:0016410; GO:0030148; GO:0046513; GO:0050291 15495 XM_029334167.2 868 593 367 817 687 Q4R899 2.52e-31 Lamin tail domain-containing protein 1 (Intermediate filament tail domain-containing protein 1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0005882 15496 XM_044324955.1 57 10 6 41 20 NA NA NA NA NA NA 15497 XM_044313635.1 73 54 28 44 44 NA NA NA NA NA NA 15498 XM_044320103.1 96 607 94 400 552 NA NA NA NA NA NA 15499 XR_006393161.1 38 31 33 52 2 NA NA NA NA NA NA 15500 XM_029354438.2 14 1 3 4 40 NA NA NA NA NA NA 15501 XR_006395974.1 192 414 429 354 286 NA NA NA NA NA NA 15502 XM_044321083.1 1428 786 558 694 557 A7RIT9 2.82e-116 3-hydroxyanthranilate 3,4-dioxygenase (EC 1.13.11.6) (3-hydroxyanthranilate oxygenase) (3-HAO) (3-hydroxyanthranilic acid dioxygenase) (HAD) Nematostella vectensis (Starlet sea anemone) 'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; anthranilate metabolic process [GO:0043420]; quinolinate biosynthetic process [GO:0019805]; quinolinate metabolic process [GO:0046874]; tryptophan catabolic process [GO:0006569] GO:0000334; GO:0005737; GO:0006569; GO:0008198; GO:0019805; GO:0034354; GO:0043420; GO:0046874 15503 XM_029327685.2 17 7 17 7 36 NA NA NA NA NA NA 15504 XM_044312324.1 4 1 49 22 2 NA NA NA NA NA NA 15505 XR_006393713.1 28 0 8 18 28 NA NA NA NA NA NA 15506 XR_003824828.2 1 18 36 33 68 NA NA NA NA NA NA 15507 XM_044316651.1 3155 492 348 1016 1834 NA NA NA NA NA NA 15508 XM_029353493.2 22 0 44 0 19 NA NA NA NA NA NA 15509 XM_029340041.2 4213 7704 2773 5471 1837 O35738 6.01e-45 Krueppel-like factor 12 (Transcriptional repressor AP-2rep) Mus musculus (Mouse) negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000977; GO:0000978; GO:0000981; GO:0001227; GO:0003677; GO:0003700; GO:0005654; GO:0005829; GO:0006355; GO:0006357; GO:0045944; GO:0046872; GO:1990837 15510 XM_029357857.2 0 1133 386 597 441 Q8N0W3 0 L-fucose kinase (Fucokinase) (EC 2.7.1.52) Homo sapiens (Human) carbohydrate phosphorylation [GO:0046835]; GDP-L-fucose salvage [GO:0042352]; response to dopamine [GO:1903350] GO:0005524; GO:0005829; GO:0042352; GO:0046835; GO:0050201; GO:1903350 15511 XM_044316222.1 1915 949 905 2948 1412 P40818 1.61e-131 Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.4.19.12) (Deubiquitinating enzyme 8) (Ubiquitin isopeptidase Y) (hUBPy) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) Homo sapiens (Human) cellular response to dexamethasone stimulus [GO:0071549]; cellular response to nerve growth factor stimulus [GO:1990090]; endosome organization [GO:0007032]; mitotic cytokinesis [GO:0000281]; negative regulation of lysosomal protein catabolic process [GO:1905166]; positive regulation of amyloid fibril formation [GO:1905908]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; Ras protein signal transduction [GO:0007265]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein stability [GO:0031647]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000281; GO:0004197; GO:0004843; GO:0005634; GO:0005737; GO:0005769; GO:0005829; GO:0006511; GO:0007032; GO:0007265; GO:0014069; GO:0016579; GO:0017124; GO:0019897; GO:0030496; GO:0031313; GO:0031647; GO:0032880; GO:0043197; GO:0045296; GO:0070536; GO:0071108; GO:0071549; GO:0090263; GO:0098978; GO:0099576; GO:1905166; GO:1905908; GO:1990090 15512 XM_029342543.2 32 0 0 12 0 Q9EQD2 1.55e-33 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 15513 XM_044315573.1 2 0 8 6 2 NA NA NA NA NA NA 15514 XM_029330068.2 0 13 7 18 15 NA NA NA NA NA NA 15515 XM_044326741.1 265 84 148 93 131 NA NA NA NA NA NA 15516 XM_044307224.1 781 492 374 966 757 NA NA NA NA NA NA 15517 XM_044308215.1 25 0 0 0 0 B1AS42 8.99e-71 NADH-cytochrome b5 reductase-like (EC 1.6.2.2) Mus musculus (Mouse) NA GO:0004128; GO:0005654 15518 XM_044326344.1 1112 674 424 283 349 Q0KHY3 1.51e-87 Protein mesh Drosophila melanogaster (Fruit fly) cell-matrix adhesion [GO:0007160]; smooth septate junction assembly [GO:0090528] GO:0005615; GO:0005920; GO:0007160; GO:0016327; GO:0090528 15519 XM_029345162.2 1724 1090 1065 2386 1957 P29145 7.42e-175 PC3-like endoprotease variant B (EC 3.4.21.-) (SPC3) Hydra vulgaris (Hydra) (Hydra attenuata) proteolysis [GO:0006508] GO:0004252; GO:0006508 15520 XM_044325308.1 1261 1519 707 1110 844 Q4V7N4 3.85e-44 Translation machinery-associated protein 16 Xenopus laevis (African clawed frog) ribosomal large subunit biogenesis [GO:0042273] GO:0005634; GO:0042273; GO:1990275 15521 XM_029343360.2 124 6 15 194 67 Q95029 1.45e-90 Cathepsin L (EC 3.4.22.15) (Cysteine proteinase 1) [Cleaved into: Cathepsin L heavy chain; Cathepsin L light chain] Drosophila melanogaster (Fruit fly) digestion [GO:0007586]; immune response [GO:0006955]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603] GO:0004197; GO:0005615; GO:0005764; GO:0006508; GO:0006955; GO:0007586; GO:0008233; GO:0008234; GO:0045169; GO:0051603 15522 XR_006395643.1 1033 625 819 1559 621 NA NA NA NA NA NA 15523 XM_029341833.2 14 1 4 9 16 NA NA NA NA NA NA 15524 XM_029349878.2 19 22 20 33 75 P79218 3.36e-28 Substance-K receptor (SKR) (NK-2 receptor) (NK-2R) (Neurokinin A receptor) (Tachykinin receptor 2) Oryctolagus cuniculus (Rabbit) positive regulation of flagellated sperm motility [GO:1902093]; regulation of uterine smooth muscle contraction [GO:0070472] GO:0004995; GO:0005886; GO:0061827; GO:0070472; GO:0097225; GO:1902093 15525 XM_029341877.2 304 108 609 199 2115 NA NA NA NA NA NA 15526 XM_044326328.1 200 130 35 223 139 NA NA NA NA NA NA 15527 XR_006391864.1 0 16 5 5 0 NA NA NA NA NA NA 15528 XR_006396103.1 113 11 0 0 20 NA NA NA NA NA NA 15529 XM_044324374.1 0 0 0 6 17 NA NA NA NA NA NA 15530 XM_044328021.1 148 113 72 121 259 Q96FG2 4.33e-81 ELMO domain-containing protein 3 (RNA-binding motif and ELMO domain-containing protein 1) (RNA-binding motif protein 29) (RNA-binding protein 29) Homo sapiens (Human) NA GO:0005737; GO:0005856; GO:0005886; GO:0032420; GO:0060091 15531 XM_029329522.2 0 56 111 44 25 O70521 1.2e-31 Regulator of G-protein signaling 19 (RGS19) (G-alpha-interacting protein) (GAIP) Rattus norvegicus (Rat) negative regulation of signal transduction [GO:0009968]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; response to ethanol [GO:0045471] GO:0000139; GO:0001965; GO:0005096; GO:0005737; GO:0005903; GO:0008277; GO:0009968; GO:0016020; GO:0030136; GO:0045121; GO:0045471 15532 XM_044313498.1 52 10 34 8 0 NA NA NA NA NA NA 15533 XM_029339542.2 16 0 0 0 0 Q9CUX1 1.56e-33 52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (THAP domain-containing protein 0) (THAP domain-containing protein 12) Mus musculus (Mouse) NA GO:0003677; GO:0005634; GO:0046872; GO:0046983 15534 XM_029335768.2 94 150 0 351 62 Q9JME2 1.11e-49 Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4S-1) (C4ST-1) (C4ST1) Mus musculus (Mouse) apoptotic process [GO:0006915]; carbohydrate biosynthetic process [GO:0016051]; cartilage development [GO:0051216]; chondrocyte development [GO:0002063]; chondroitin sulfate biosynthetic process [GO:0030206]; chondroitin sulfate metabolic process [GO:0030204]; developmental growth [GO:0048589]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; embryonic viscerocranium morphogenesis [GO:0048703]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; polysaccharide localization [GO:0033037]; post-anal tail morphogenesis [GO:0036342]; post-embryonic development [GO:0009791]; proteoglycan biosynthetic process [GO:0030166]; regulation of cell population proliferation [GO:0042127]; respiratory gaseous exchange by respiratory system [GO:0007585]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0000139; GO:0001537; GO:0001701; GO:0002063; GO:0006915; GO:0007179; GO:0007585; GO:0008146; GO:0009791; GO:0016051; GO:0030166; GO:0030204; GO:0030206; GO:0030326; GO:0030512; GO:0033037; GO:0036342; GO:0042127; GO:0042733; GO:0043066; GO:0047756; GO:0048589; GO:0048703; GO:0048704; GO:0050659; GO:0051216 15535 XM_029347709.2 1366 1936 1558 1118 1214 P62074 3.71e-37 Mitochondrial import inner membrane translocase subunit Tim10 Rattus norvegicus (Rat) protein insertion into mitochondrial inner membrane [GO:0045039] GO:0005743; GO:0005758; GO:0032977; GO:0042719; GO:0042721; GO:0042803; GO:0045039; GO:0046872; GO:0051087 15536 XM_029351640.2 116 62 141 16 63 Q9UJT9 4.45e-99 F-box/LRR-repeat protein 7 (F-box and leucine-rich repeat protein 7) (F-box protein FBL6/FBL7) Homo sapiens (Human) cell division [GO:0051301]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic cell cycle [GO:0000278]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000086; GO:0000151; GO:0000209; GO:0000278; GO:0005813; GO:0005829; GO:0006511; GO:0016567; GO:0019005; GO:0031146; GO:0051301 15537 XM_029355499.2 141 136 76 224 6 Q9JJZ8 1.02e-139 Cyclic nucleotide-gated cation channel alpha-3 (Cone photoreceptor cGMP-gated channel subunit alpha) (Cyclic nucleotide-gated channel alpha-3) (CNG channel alpha-3) (CNG-3) (CNG3) Mus musculus (Mouse) cation transmembrane transport [GO:0098655]; cation transport [GO:0006812]; inorganic cation import across plasma membrane [GO:0098659]; ion transmembrane transport [GO:0034220]; response to cAMP [GO:0051591]; response to magnesium ion [GO:0032026]; retinal cone cell development [GO:0046549]; visual perception [GO:0007601] GO:0001750; GO:0005221; GO:0005222; GO:0005223; GO:0005737; GO:0005886; GO:0006812; GO:0007601; GO:0008022; GO:0017071; GO:0030425; GO:0030553; GO:0032026; GO:0034220; GO:0043025; GO:0043194; GO:0043204; GO:0044877; GO:0046549; GO:0051591; GO:0097386; GO:0098655; GO:0098659; GO:0120199; GO:1902495 15538 XR_006394710.1 1 16 0 5 9 NA NA NA NA NA NA 15539 XM_029337155.2 2186 1785 1525 1804 1795 Q5NC83 3.03e-30 Spermatogenesis-associated protein 48 (Post-meiotic spermatogenesis protein 1) Mus musculus (Mouse) cell differentiation [GO:0030154]; spermatogenesis [GO:0007283] GO:0007283; GO:0030154 15540 XM_044315378.1 5 0 25 2 38 NA NA NA NA NA NA 15541 XM_029355710.2 130 0 6 0 203 Q5XGE2 4.46e-140 U3 small nucleolar RNA-associated protein 15 homolog Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) rRNA processing [GO:0006364] GO:0005730; GO:0006364 15542 XM_029329841.2 5770 5212 3951 4399 3735 Q9TT38 2.19e-178 Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase); Lysophospholipase (EC 3.1.1.5)] Oryctolagus cuniculus (Rabbit) arachidonic acid metabolic process [GO:0019369]; glycerol metabolic process [GO:0006071]; leukotriene biosynthetic process [GO:0019370]; monoacylglycerol biosynthetic process [GO:0006640]; phosphatidylcholine catabolic process [GO:0034638]; phosphatidylglycerol catabolic process [GO:0034478]; prostaglandin biosynthetic process [GO:0001516] GO:0000139; GO:0001516; GO:0004622; GO:0005509; GO:0005544; GO:0005635; GO:0005737; GO:0006071; GO:0006640; GO:0008374; GO:0010314; GO:0019369; GO:0019370; GO:0032266; GO:0034478; GO:0034638; GO:0047498; GO:0047499; GO:0070273; GO:0102545; GO:1902387 15543 XM_029331373.2 444 388 272 537 552 Q96NI8 1.13e-56 Zinc finger protein 570 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 15544 XM_029331373.2 444 388 272 537 552 Q96NI8 6.92e-50 Zinc finger protein 570 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 15545 XM_029331373.2 444 388 272 537 552 Q96NI8 2.74e-48 Zinc finger protein 570 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 15546 XM_029331373.2 444 388 272 537 552 Q96NI8 2.27e-44 Zinc finger protein 570 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 15547 XM_029331373.2 444 388 272 537 552 Q96NI8 5.74e-39 Zinc finger protein 570 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 15548 XM_029358668.2 307 172 356 422 477 B3EWZ3 5.59e-131 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 15549 XM_029358668.2 307 172 356 422 477 B3EWZ3 4.4e-107 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 15550 XM_029358668.2 307 172 356 422 477 B3EWZ3 2.79e-101 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 15551 XM_029358668.2 307 172 356 422 477 B3EWZ3 5.29e-87 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 15552 XM_044321131.1 0 14 4 0 0 M9NDE3 2.13e-23 Protein bark beetle (Protein anakonda) Drosophila melanogaster (Fruit fly) cell-cell junction maintenance [GO:0045217]; liquid clearance, open tracheal system [GO:0035002]; regulation of tube length, open tracheal system [GO:0035159]; response to endoplasmic reticulum stress [GO:0034976]; tricellular tight junction assembly [GO:1904274] GO:0005044; GO:0005912; GO:0005918; GO:0005923; GO:0016328; GO:0030246; GO:0034976; GO:0035002; GO:0035159; GO:0045217; GO:0061689; GO:1904274 15553 XM_029346160.2 0 59 0 10 0 Q9EPI9 0 Potassium voltage-gated channel subfamily H member 5 (Ether-a-go-go potassium channel 2) (rEAG2) (Voltage-gated potassium channel subunit Kv10.2) Rattus norvegicus (Rat) potassium ion transmembrane transport [GO:0071805]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391] GO:0005249; GO:0005516; GO:0005886; GO:0009986; GO:0010389; GO:0034765; GO:0042391; GO:0044325; GO:0044877; GO:0071805 15554 XM_029338321.2 45 8 6 0 37 P35061 3.69e-56 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 15555 XM_044320180.1 202 159 60 57 47 NA NA NA NA NA NA 15556 XM_044320532.1 0 0 0 0 14 A0A1L8FZ98 1.37e-65 Peroxisome biogenesis factor 2 (EC 2.3.2.27) (EC 2.3.2.36) (Peroxin-2) Xenopus laevis (African clawed frog) pexophagy [GO:0000425]; protein import into peroxisome matrix, receptor recycling [GO:0016562]; response to amino acid starvation [GO:1990928] GO:0000425; GO:0005778; GO:0016562; GO:0046872; GO:0061630; GO:1990928 15557 XM_044314996.1 0 0 2 1 28 NA NA NA NA NA NA 15558 XM_044325910.1 4 85 17 12 22 NA NA NA NA NA NA 15559 XM_044314304.1 57 84 78 59 115 Q5U2T8 1.47e-63 Corepressor interacting with RBPJ 1 (CBF1-interacting corepressor) Rattus norvegicus (Rat) in utero embryonic development [GO:0001701]; mRNA processing [GO:0006397]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; RNA splicing [GO:0008380] GO:0000122; GO:0001701; GO:0003714; GO:0005634; GO:0005737; GO:0005813; GO:0006397; GO:0008380; GO:0016607; GO:0019901; GO:0032991; GO:0042826; GO:0044877; GO:0045892 15560 XM_029326879.2 57 23 0 18 15 Q3V2Q8 6.45e-47 NEDD4-binding protein 2-like 1 Mus musculus (Mouse) NA NA 15561 XM_029354103.2 0 22 0 0 81 Q91175 8.33e-48 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (MAR1) Oryzias latipes (Japanese rice fish) (Japanese killifish) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of vasoconstriction [GO:0045907] GO:0001996; GO:0004930; GO:0004937; GO:0005886; GO:0007200; GO:0007204; GO:0007267; GO:0043410; GO:0045907; GO:0071880 15562 XM_044319252.1 0 403 0 136 0 NA NA NA NA NA NA 15563 XM_044326055.1 522 511 0 742 968 NA NA NA NA NA NA 15564 XM_044307853.1 7 7 10 25 18 NA NA NA NA NA NA 15565 XM_044328405.1 6 0 0 0 20 NA NA NA NA NA NA 15566 XM_029355098.2 53 67 51 115 60 NA NA NA NA NA NA 15567 XM_029358063.2 2887 2079 1699 2680 2727 P41252 0 Isoleucine--tRNA ligase, cytoplasmic (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IRS) (IleRS) Homo sapiens (Human) isoleucyl-tRNA aminoacylation [GO:0006428]; osteoblast differentiation [GO:0001649]; tRNA aminoacylation for protein translation [GO:0006418] GO:0000049; GO:0001649; GO:0002161; GO:0004822; GO:0005524; GO:0005654; GO:0005737; GO:0005829; GO:0006418; GO:0006428; GO:0016020; GO:0017101; GO:0051020; GO:0070062 15568 XM_044325446.1 83 73 31 56 51 Q9CWY4 2.11e-21 Gem-associated protein 7 (Gemin-7) Mus musculus (Mouse) spliceosomal snRNP assembly [GO:0000387] GO:0000387; GO:0005654; GO:0005737; GO:0005829; GO:0016604; GO:0032797; GO:0034719; GO:0097504; GO:0120114 15569 XM_044312646.1 205 188 95 149 361 NA NA NA NA NA NA 15570 XM_044319759.1 120 166 5 161 145 Q6PFY8 8.02e-42 Tripartite motif-containing protein 45 Mus musculus (Mouse) bone development [GO:0060348]; positive regulation of DNA-templated transcription [GO:0045893] GO:0000785; GO:0004842; GO:0005654; GO:0005829; GO:0008270; GO:0045171; GO:0045893; GO:0060348 15571 XM_029349835.2 1750 3376 1527 3963 3696 NA NA NA NA NA NA 15572 XM_029338871.2 2908 2124 1303 2180 2121 Q8IVB5 9.22e-131 LIX1-like protein Homo sapiens (Human) autophagosome maturation [GO:0097352] GO:0005737; GO:0097352 15573 XR_006392386.1 79 114 108 9 55 NA NA NA NA NA NA 15574 XM_044315879.1 6 29 79 0 33 NA NA NA NA NA NA 15575 XM_029329910.2 926 650 543 752 403 B8VIU6 5.46e-154 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 15576 XM_029326527.2 8 0 0 0 0 P19217 6.84e-51 Sulfotransferase 1E1 (ST1E1) (EC 2.8.2.4) (Estrogen sulfotransferase) (Sulfotransferase, estrogen-preferring) Bos taurus (Bovine) estrogen metabolic process [GO:0008210]; sulfation [GO:0051923] GO:0004062; GO:0004304; GO:0005496; GO:0005737; GO:0005829; GO:0008146; GO:0008210; GO:0050294; GO:0051923 15577 XM_044324481.1 89 145 61 70 46 Q96AY4 9.81e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15578 XM_044324481.1 89 145 61 70 46 Q96AY4 1.26e-71 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15579 XM_044324481.1 89 145 61 70 46 Q96AY4 6.53e-71 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15580 XM_044324481.1 89 145 61 70 46 Q96AY4 8.82e-71 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15581 XM_044324481.1 89 145 61 70 46 Q96AY4 1.14e-63 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15582 XM_044324481.1 89 145 61 70 46 Q96AY4 8.82e-62 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15583 XM_044324481.1 89 145 61 70 46 Q96AY4 1.46e-61 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15584 XM_044324481.1 89 145 61 70 46 Q96AY4 9.21e-56 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15585 XM_044324481.1 89 145 61 70 46 Q96AY4 4.6e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15586 XM_029346851.2 9 4 6 14 12 NA NA NA NA NA NA 15587 XM_044324956.1 35 19 13 68 47 Q96AY4 7.8e-163 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15588 XM_044324956.1 35 19 13 68 47 Q96AY4 5.85e-161 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15589 XM_044324956.1 35 19 13 68 47 Q96AY4 1e-147 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15590 XM_044324956.1 35 19 13 68 47 Q96AY4 3.04e-108 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15591 XM_044324956.1 35 19 13 68 47 Q96AY4 7.54e-104 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15592 XM_044324956.1 35 19 13 68 47 Q96AY4 6.81e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15593 XM_044322680.1 360 182 385 307 816 Q6PQD5 0 Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated homolog) (A-T mutated homolog) Sus scrofa (Pig) cellular response to DNA damage stimulus [GO:0006974]; DNA damage checkpoint signaling [GO:0000077]; DNA repair [GO:0006281]; histone mRNA catabolic process [GO:0071044]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; mitotic spindle assembly checkpoint signaling [GO:0007094]; negative regulation of TORC1 signaling [GO:1904262]; peptidyl-serine phosphorylation [GO:0018105]; pexophagy [GO:0000425]; pre-B cell allelic exclusion [GO:0002331]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; response to ionizing radiation [GO:0010212]; signal transduction in response to DNA damage [GO:0042770]; telomere maintenance [GO:0000723]; translation [GO:0006412] GO:0000077; GO:0000425; GO:0000723; GO:0002331; GO:0003677; GO:0003735; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005782; GO:0005813; GO:0005840; GO:0006281; GO:0006412; GO:0006468; GO:0006974; GO:0007094; GO:0008630; GO:0010212; GO:0016303; GO:0018105; GO:0031410; GO:0042770; GO:0046777; GO:0047485; GO:0071044; GO:0106310; GO:1904262 15594 XM_044312694.1 27 35 51 71 64 NA NA NA NA NA NA 15595 XR_006398070.1 1 2 10 10 18 NA NA NA NA NA NA 15596 XM_029332418.2 972 1148 759 928 1429 NA NA NA NA NA NA 15597 XM_029356692.2 2703 4400 1633 4323 3903 Q8BTK5 6.02e-51 SET and MYND domain-containing protein 4 (EC 2.1.1.-) Mus musculus (Mouse) heart development [GO:0007507]; methylation [GO:0032259] GO:0005634; GO:0005737; GO:0007507; GO:0008168; GO:0032259; GO:0042826; GO:0046872 15598 XM_044311721.1 26 39 537 93 619 NA NA NA NA NA NA 15599 XM_029353727.2 488 246 328 330 296 Q8BTQ0 8.76e-46 Polycomb group RING finger protein 3 (RING finger protein 3A) Mus musculus (Mouse) histone H2A-K119 monoubiquitination [GO:0036353]; inactivation of X chromosome by genomic imprinting [GO:0060819]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0005634; GO:0005654; GO:0006357; GO:0031519; GO:0035102; GO:0036353; GO:0046872; GO:0060819 15600 XR_006395381.1 15 5 13 11 23 NA NA NA NA NA NA 15601 XM_044307165.1 161 161 274 169 913 NA NA NA NA NA NA 15602 XM_029352625.2 99 186 113 314 108 NA NA NA NA NA NA 15603 XR_006396533.1 2494 4011 1908 6070 3317 NA NA NA NA NA NA 15604 XM_029337554.2 806 444 169 667 747 Q13247 7.47e-47 Serine/arginine-rich splicing factor 6 (Pre-mRNA-splicing factor SRP55) (Splicing factor, arginine/serine-rich 6) Homo sapiens (Human) alternative mRNA splicing, via spliceosome [GO:0000380]; mRNA splice site selection [GO:0006376]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of cell death [GO:0060548]; negative regulation of keratinocyte differentiation [GO:0045617]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of type B pancreatic cell apoptotic process [GO:2000675]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of keratinocyte proliferation [GO:0010837]; regulation of wound healing [GO:0061041]; response to insulin [GO:0032868] GO:0000380; GO:0000381; GO:0000398; GO:0003723; GO:0003729; GO:0005654; GO:0006376; GO:0010837; GO:0016607; GO:0032868; GO:0036002; GO:0045617; GO:0048025; GO:0060501; GO:0060548; GO:0061041; GO:2000675 15605 XR_006396001.1 2 9 13 7 24 NA NA NA NA NA NA 15606 XM_029355621.2 899 397 440 417 769 NA NA NA NA NA NA 15607 XM_029347938.2 333 417 119 395 86 NA NA NA NA NA NA 15608 XM_044326220.1 26 11 31 61 95 NA NA NA NA NA NA 15609 XM_044324047.1 855 0 470 9 508 D3ZZL9 9.65e-90 GRIP and coiled-coil domain-containing protein 2 (185 kDa Golgi coiled-coil protein) Rattus norvegicus (Rat) Golgi ribbon formation [GO:0090161]; late endosome to Golgi transport [GO:0034499]; microtubule anchoring [GO:0034453]; microtubule organizing center organization [GO:0031023]; protein localization to Golgi apparatus [GO:0034067]; protein targeting to lysosome [GO:0006622]; recycling endosome to Golgi transport [GO:0071955]; regulation of protein exit from endoplasmic reticulum [GO:0070861]; retrograde transport, endosome to Golgi [GO:0042147] GO:0005794; GO:0005802; GO:0005829; GO:0006622; GO:0016020; GO:0031023; GO:0034067; GO:0034453; GO:0034499; GO:0042147; GO:0042802; GO:0070861; GO:0071955; GO:0090161 15610 XM_044316522.1 0 0 10 0 0 NA NA NA NA NA NA 15611 XM_029347766.2 1 1 0 26 11 NA NA NA NA NA NA 15612 XM_029329070.2 1158 835 983 1054 803 NA NA NA NA NA NA 15613 XM_029339355.2 203 151 88 153 135 Q08BL7 2.39e-113 Glycerate kinase (EC 2.7.1.31) Danio rerio (Zebrafish) (Brachydanio rerio) protein phosphorylation [GO:0006468] GO:0005524; GO:0005737; GO:0006468; GO:0008887 15614 XM_044326442.1 5 26 45 0 4 NA NA NA NA NA NA 15615 XM_044321284.1 196 53 76 70 148 Q7RTR2 7.67e-41 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 15616 XM_044321284.1 196 53 76 70 148 Q7RTR2 1.84e-30 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 15617 XM_044321284.1 196 53 76 70 148 Q7RTR2 9.52e-29 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 15618 XM_044308994.1 327 122 115 198 144 NA NA NA NA NA NA 15619 XM_044306876.1 0 0 90 0 193 Q15858 0 Sodium channel protein type 9 subunit alpha (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1) (PN1) (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) Homo sapiens (Human) behavioral response to formalin induced pain [GO:0061368]; circadian rhythm [GO:0007623]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; inflammatory response [GO:0006954]; membrane depolarization during action potential [GO:0086010]; negative regulation of action potential [GO:0045759]; neuronal action potential [GO:0019228]; post-embryonic development [GO:0009791]; regulation of ion transmembrane transport [GO:0034765]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to toxic substance [GO:0009636]; sensory perception of pain [GO:0019233]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814] GO:0001518; GO:0005244; GO:0005248; GO:0005886; GO:0006814; GO:0006954; GO:0007623; GO:0009408; GO:0009409; GO:0009636; GO:0009791; GO:0019228; GO:0019233; GO:0030424; GO:0031402; GO:0034765; GO:0035725; GO:0045759; GO:0050965; GO:0050974; GO:0061368; GO:0086010 15620 XM_044306876.1 0 0 90 0 193 Q15858 1.52e-67 Sodium channel protein type 9 subunit alpha (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1) (PN1) (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) Homo sapiens (Human) behavioral response to formalin induced pain [GO:0061368]; circadian rhythm [GO:0007623]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; inflammatory response [GO:0006954]; membrane depolarization during action potential [GO:0086010]; negative regulation of action potential [GO:0045759]; neuronal action potential [GO:0019228]; post-embryonic development [GO:0009791]; regulation of ion transmembrane transport [GO:0034765]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to toxic substance [GO:0009636]; sensory perception of pain [GO:0019233]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814] GO:0001518; GO:0005244; GO:0005248; GO:0005886; GO:0006814; GO:0006954; GO:0007623; GO:0009408; GO:0009409; GO:0009636; GO:0009791; GO:0019228; GO:0019233; GO:0030424; GO:0031402; GO:0034765; GO:0035725; GO:0045759; GO:0050965; GO:0050974; GO:0061368; GO:0086010 15621 XM_044319947.1 7806 7617 5673 7192 8222 P11833 0 Tubulin beta chain (Beta-tubulin) Paracentrotus lividus (Common sea urchin) microtubule-based process [GO:0007017] GO:0003924; GO:0005200; GO:0005525; GO:0005737; GO:0005874; GO:0007017; GO:0046872 15622 XM_029339326.2 0 0 18 39 0 NA NA NA NA NA NA 15623 XM_044321609.1 6010 8169 3806 4693 5095 NA NA NA NA NA NA 15624 XM_029353611.2 1565 1240 1803 1692 2437 Q08BW0 8.99e-100 OTU domain-containing protein 5-A (EC 3.4.19.12) (Deubiquitinating enzyme A) (DUBA) Danio rerio (Zebrafish) (Brachydanio rerio) protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; response to lipopolysaccharide [GO:0032496] GO:0004843; GO:0016579; GO:0032496; GO:0061578; GO:0070536; GO:0071108 15625 XR_006397886.1 285 39 129 168 170 Q9BLG4 1.15e-43 Ammonium transporter 1 Dictyostelium discoideum (Social amoeba) ammonium transmembrane transport [GO:0072488]; asexual reproduction [GO:0019954]; positive regulation of aggregate size involved in sorocarp development [GO:0031159]; secretion [GO:0046903]; sporulation resulting in formation of a cellular spore [GO:0030435] GO:0000421; GO:0005774; GO:0005886; GO:0008519; GO:0019954; GO:0030435; GO:0030670; GO:0031159; GO:0036020; GO:0046903; GO:0072488; GO:0140220 15626 XR_006397778.1 139 33 75 176 35 NA NA NA NA NA NA 15627 XM_029330334.2 917 844 615 1207 1525 Q6GPD0 6.63e-161 Rho GTPase-activating protein 32 (Rho-type GTPase-activating protein 32) (Rho/Cdc42/Rac GTPase-activating protein RICS) Xenopus laevis (African clawed frog) signal transduction [GO:0007165] GO:0005096; GO:0005737; GO:0005886; GO:0007165; GO:0014069; GO:1901981 15628 XM_044328802.1 44 7 44 30 95 Q96DM1 1.83e-32 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 15629 XM_044316924.1 1275 5998 988 2420 1303 NA NA NA NA NA NA 15630 XM_029348355.2 16 5 4 16 80 NA NA NA NA NA NA 15631 XM_029341535.2 53 80 5 87 30 Q5ZML9 2.86e-140 Actin-histidine N-methyltransferase (EC 2.1.1.85) (Protein-L-histidine N-tele-methyltransferase) (SET domain-containing protein 3) Gallus gallus (Chicken) actin modification [GO:0030047]; peptidyl-histidine methylation [GO:0018021]; peptidyl-lysine dimethylation [GO:0018027]; peptidyl-lysine monomethylation [GO:0018026]; peptidyl-lysine trimethylation [GO:0018023]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0003713; GO:0003779; GO:0005737; GO:0016279; GO:0018021; GO:0018023; GO:0018026; GO:0018027; GO:0018064; GO:0030047; GO:0042800; GO:0045893; GO:0045944; GO:0046975 15632 XM_044329038.1 21 25 40 3 36 NA NA NA NA NA NA 15633 XM_029357871.2 475 162 187 404 265 A8KBE0 1.94e-34 Oxidation resistance protein 1 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005739 15634 XM_044313890.1 20 2 30 25 22 NA NA NA NA NA NA 15635 XR_006393114.1 207 211 134 198 172 NA NA NA NA NA NA 15636 XM_044317304.1 135 41 22 140 0 A0A2B4SES9 4.26e-95 NA NA NA NA 15637 XM_044313168.1 1 7 0 0 14 NA NA NA NA NA NA 15638 XM_044307848.1 73 44 78 122 55 NA NA NA NA NA NA 15639 XM_029327295.2 105 495 358 725 299 NA NA NA NA NA NA 15640 XM_044314175.1 0 13 3 12 67 Q9VBW3 3.52e-83 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 15641 XM_029330472.2 3211 2858 1565 2739 2816 Q9D0R2 0 Threonine--tRNA ligase 1, cytoplasmic (EC 6.1.1.3) (Threonine--tRNA ligase, cytoplasmic) (Threonyl-tRNA synthetase) (ThrRS) (Threonyl-tRNA synthetase 1) Mus musculus (Mouse) threonyl-tRNA aminoacylation [GO:0006435] GO:0004829; GO:0005524; GO:0005737; GO:0006435; GO:0008270; GO:0042802 15642 XM_029338897.2 13 125 19 26 17 NA NA NA NA NA NA 15643 XM_044312920.1 53 39 61 129 150 P15374 4.45e-90 Ubiquitin carboxyl-terminal hydrolase isozyme L3 (UCH-L3) (EC 3.4.19.12) (Ubiquitin thioesterase L3) Homo sapiens (Human) post-translational protein modification [GO:0043687]; protein catabolic process [GO:0030163]; protein deubiquitination [GO:0016579]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004843; GO:0005654; GO:0005737; GO:0005829; GO:0006511; GO:0008233; GO:0016567; GO:0016579; GO:0019784; GO:0030163; GO:0043130; GO:0043687 15644 XM_044320824.1 113 0 36 0 9 NA NA NA NA NA NA 15645 XR_003828553.2 4 2 12 4 22 NA NA NA NA NA NA 15646 XM_044315952.1 1216 606 93 415 526 NA NA NA NA NA NA 15647 XM_044325714.1 111 561 73 504 393 Q9UJT0 0 Tubulin epsilon chain (Epsilon-tubulin) Homo sapiens (Human) centrosome cycle [GO:0007098]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278] GO:0000226; GO:0000242; GO:0000278; GO:0005200; GO:0005525; GO:0005737; GO:0005874; GO:0007098 15648 XM_044316643.1 45 22 0 6 4 P30937 2.29e-21 Somatostatin receptor type 4 (SS-4-R) (SS4-R) (SS4R) Rattus norvegicus (Rat) cell migration [GO:0016477]; cellular response to glucocorticoid stimulus [GO:0071385]; forebrain development [GO:0030900]; negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0106072]; neuropeptide signaling pathway [GO:0007218]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0004930; GO:0004994; GO:0005737; GO:0005886; GO:0007218; GO:0016477; GO:0030900; GO:0042277; GO:0042923; GO:0043005; GO:0070374; GO:0071385; GO:0090238; GO:0106072 15649 XM_044316568.1 3 0 5 0 34 NA NA NA NA NA NA 15650 XR_003823020.2 3 7 14 11 16 NA NA NA NA NA NA 15651 XM_029357793.2 49 77 0 0 0 Q9EQD2 5.81e-46 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 15652 XM_029339221.2 290 59 35 251 129 NA NA NA NA NA NA 15653 XM_029329209.2 165 99 126 383 196 NA NA NA NA NA NA 15654 XM_044325801.1 0 1 0 0 28 NA NA NA NA NA NA 15655 XM_029345651.2 66 88 70 48 295 NA NA NA NA NA NA 15656 XM_044315221.1 4 89 157 304 368 NA NA NA NA NA NA 15657 XM_044315402.1 3 1 0 0 6 Q8I7P9 1.58e-27 Retrovirus-related Pol polyprotein from transposon opus [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508]; transposition, DNA-mediated [GO:0006313] GO:0003676; GO:0003887; GO:0003964; GO:0004519; GO:0005634; GO:0006313; GO:0006508; GO:0008233; GO:0015074; GO:0042575 15658 XR_006392994.1 41 2 25 5 151 NA NA NA NA NA NA 15659 XR_006395351.1 537 316 220 344 197 P41386 3.44e-89 Tubulin beta chain (Beta-tubulin) Haliotis discus (Abalone) (Nordotis discus) microtubule-based process [GO:0007017] GO:0003924; GO:0005200; GO:0005525; GO:0005737; GO:0005874; GO:0007017 15660 XM_044323858.1 40 7 17 10 30 Q8K2X2 2.12e-54 RNA-binding protein 48 Mus musculus (Mouse) NA GO:0003723; GO:0005654 15661 XM_044323363.1 209 98 119 193 269 B4F769 0 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.4.-) (HepA-related protein) (Sucrose nonfermenting protein 2-like 1) Rattus norvegicus (Rat) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; regulation of transcription by RNA polymerase II [GO:0006357]; replication fork processing [GO:0031297]; replication fork protection [GO:0048478] GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0005662; GO:0006281; GO:0006303; GO:0006357; GO:0006974; GO:0008094; GO:0016787; GO:0031297; GO:0035861; GO:0036310; GO:0043596; GO:0048478; GO:0140658 15662 XR_006397707.1 691 581 797 560 228 NA NA NA NA NA NA 15663 XR_006394688.1 66 0 27 32 74 NA NA NA NA NA NA 15664 XR_006393868.1 67 57 94 0 128 NA NA NA NA NA NA 15665 XM_029340372.2 0 32 211 253 44 NA NA NA NA NA NA 15666 XM_044325030.1 0 4 109 0 9 NA NA NA NA NA NA 15667 XM_029332126.2 11 0 0 0 0 O15178 1.19e-118 T-box transcription factor T (Brachyury protein) (Protein T) Homo sapiens (Human) anterior/posterior axis specification, embryo [GO:0008595]; cardiac muscle cell myoblast differentiation [GO:0060379]; cell fate specification [GO:0001708]; heart morphogenesis [GO:0003007]; mesoderm development [GO:0007498]; mesoderm formation [GO:0001707]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; primitive streak formation [GO:0090009]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; somitogenesis [GO:0001756] GO:0000122; GO:0000785; GO:0000978; GO:0000981; GO:0001707; GO:0001708; GO:0001756; GO:0003007; GO:0003700; GO:0005634; GO:0005654; GO:0006357; GO:0007165; GO:0007498; GO:0008595; GO:0043433; GO:0045944; GO:0060379; GO:0061629; GO:0090009; GO:1990837 15668 XR_003828189.2 0 7 0 0 0 Q6ZTW0 9.06e-30 Tubulin polyglutamylase complex subunit 1 (PGs1) Homo sapiens (Human) adult behavior [GO:0030534]; chemical synaptic transmission [GO:0007268]; protein polyglutamylation [GO:0018095]; sperm axoneme assembly [GO:0007288]; vesicle localization [GO:0051648] GO:0005737; GO:0005813; GO:0005874; GO:0007268; GO:0007288; GO:0008017; GO:0018095; GO:0030424; GO:0030425; GO:0030534; GO:0031514; GO:0045202; GO:0051648; GO:0070740 15669 XM_044316347.1 0 0 7 24 17 Q6AZB8 2.31e-29 Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0004518; GO:0005634; GO:0005737; GO:0046872 15670 XM_029350939.2 149 186 123 214 255 Q9U3S9 1.22e-52 Zinc metalloproteinase nas-6 (EC 3.4.24.-) (Nematode astacin 6) Caenorhabditis elegans pharyngeal pumping [GO:0043050]; pharynx development [GO:0060465]; proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0006508; GO:0008270; GO:0043050; GO:0060465 15671 XR_006395430.1 0 0 29 49 80 NA NA NA NA NA NA 15672 XM_044322479.1 6 11 29 8 32 NA NA NA NA NA NA 15673 XM_044317400.1 9 0 0 1 12 NA NA NA NA NA NA 15674 XM_044328739.1 83 6 10 14 13 Q96AY4 6.02e-45 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15675 XM_044328739.1 83 6 10 14 13 Q96AY4 2.91e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15676 XM_044328739.1 83 6 10 14 13 Q96AY4 3.44e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15677 XM_044328739.1 83 6 10 14 13 Q96AY4 5.03e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15678 XM_044328739.1 83 6 10 14 13 Q96AY4 2.24e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15679 XM_044328739.1 83 6 10 14 13 Q96AY4 4.39e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15680 XM_029341533.2 1404 968 1255 1719 1326 E7FDB3 1.03e-21 Nanos homolog 1 Danio rerio (Zebrafish) (Brachydanio rerio) negative regulation of translation [GO:0017148]; oogenesis [GO:0048477] GO:0003729; GO:0005737; GO:0008270; GO:0017148; GO:0030371; GO:0048471; GO:0048477; GO:0060293 15681 XM_044309055.1 210 169 79 164 159 NA NA NA NA NA NA 15682 XR_003822769.2 2244 2679 2368 1989 1796 NA NA NA NA NA NA 15683 XM_029335570.2 2125 3990 1811 6627 5891 P55006 1.62e-77 Retinol dehydrogenase 7 (EC 1.1.1.105) (Retinol dehydrogenase 3) (Retinol dehydrogenase type III) (RODH III) Rattus norvegicus (Rat) retinol metabolic process [GO:0042572]; steroid metabolic process [GO:0008202] GO:0004745; GO:0005783; GO:0008202; GO:0016491; GO:0042572; GO:0043231 15684 XM_044309268.1 147 129 26 44 23 NA NA NA NA NA NA 15685 XR_006393254.1 86 7 10 8 22 NA NA NA NA NA NA 15686 XM_044319863.1 26 27 20 19 198 NA NA NA NA NA NA 15687 XM_029357286.2 2017 764 1618 2562 1520 P31646 2.27e-120 Sodium- and chloride-dependent GABA transporter 2 (GAT-2) (Solute carrier family 6 member 13) Rattus norvegicus (Rat) amino acid import across plasma membrane [GO:0089718]; creatine transmembrane transport [GO:0015881]; gamma-aminobutyric acid import [GO:0051939]; monocarboxylic acid transport [GO:0015718]; neurotransmitter transport [GO:0006836]; nitrogen compound transport [GO:0071705]; positive regulation of necrotic cell death [GO:0010940]; sodium ion transmembrane transport [GO:0035725]; taurine transport [GO:0015734] GO:0005283; GO:0005308; GO:0005332; GO:0005368; GO:0005369; GO:0005886; GO:0006836; GO:0008028; GO:0010940; GO:0015171; GO:0015185; GO:0015718; GO:0015734; GO:0015881; GO:0016323; GO:0035725; GO:0042165; GO:0043005; GO:0051939; GO:0071705; GO:0089718 15688 XM_029331093.2 776 728 378 719 745 P70032 0 Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Plx1) (Polo-like kinase 1) (PLK-1) Xenopus laevis (African clawed frog) centrosome cycle [GO:0007098]; G2/M transition of mitotic cell cycle [GO:0000086]; microtubule bundle formation [GO:0001578]; mitotic cell cycle [GO:0000278]; mitotic cytokinesis [GO:0000281]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oocyte maturation [GO:0001556]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; protein localization to chromatin [GO:0071168]; protein phosphorylation [GO:0006468] GO:0000086; GO:0000122; GO:0000278; GO:0000281; GO:0000776; GO:0001556; GO:0001578; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005819; GO:0006468; GO:0007095; GO:0007098; GO:0008017; GO:0019901; GO:0030496; GO:0043066; GO:0051233; GO:0071168; GO:0106310; GO:1904668 15689 XR_006394981.1 170 256 0 185 91 NA NA NA NA NA NA 15690 XM_029328415.2 479 632 486 575 930 A3KP77 1.4e-75 Oxidoreductase NAD-binding domain-containing protein 1 (EC 1.-.-.-) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0016491 15691 XM_044306824.1 1808 1600 1185 2751 2336 Q6ZPV2 0 Chromatin-remodeling ATPase INO80 (EC 3.6.4.-) (DNA helicase-related INO80 complex homolog 1) (DNA helicase-related protein INO80) Mus musculus (Mouse) cell division [GO:0051301]; cellular response to ionizing radiation [GO:0071479]; cellular response to UV [GO:0034644]; chromatin remodeling [GO:0006338]; DNA repair [GO:0006281]; DNA-templated transcription [GO:0006351]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; mitotic sister chromatid segregation [GO:0000070]; positive regulation of cell growth [GO:0030307]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of nuclear cell cycle DNA replication [GO:0010571]; positive regulation of telomere maintenance in response to DNA damage [GO:1904507]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell cycle [GO:0051726]; regulation of chromosome organization [GO:0033044]; regulation of DNA repair [GO:0006282]; regulation of DNA replication [GO:0006275]; regulation of DNA strand elongation [GO:0060382]; regulation of embryonic development [GO:0045995]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of transcription from RNA polymerase II promoter in response to stress [GO:0043618]; spindle assembly [GO:0051225]; telomere maintenance [GO:0000723]; UV-damage excision repair [GO:0070914] GO:0000070; GO:0000723; GO:0000724; GO:0003677; GO:0003779; GO:0005524; GO:0005634; GO:0005654; GO:0005819; GO:0005829; GO:0005874; GO:0006275; GO:0006281; GO:0006282; GO:0006302; GO:0006338; GO:0006351; GO:0008094; GO:0010571; GO:0016604; GO:0016887; GO:0030307; GO:0031011; GO:0033044; GO:0034644; GO:0042393; GO:0043014; GO:0043618; GO:0045739; GO:0045893; GO:0045944; GO:0045995; GO:0051225; GO:0051301; GO:0051726; GO:0060382; GO:0070914; GO:0071479; GO:0140658; GO:1904507; GO:2000045 15692 XM_044306824.1 1808 1600 1185 2751 2336 Q6ZPV2 9.62e-113 Chromatin-remodeling ATPase INO80 (EC 3.6.4.-) (DNA helicase-related INO80 complex homolog 1) (DNA helicase-related protein INO80) Mus musculus (Mouse) cell division [GO:0051301]; cellular response to ionizing radiation [GO:0071479]; cellular response to UV [GO:0034644]; chromatin remodeling [GO:0006338]; DNA repair [GO:0006281]; DNA-templated transcription [GO:0006351]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; mitotic sister chromatid segregation [GO:0000070]; positive regulation of cell growth [GO:0030307]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of nuclear cell cycle DNA replication [GO:0010571]; positive regulation of telomere maintenance in response to DNA damage [GO:1904507]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell cycle [GO:0051726]; regulation of chromosome organization [GO:0033044]; regulation of DNA repair [GO:0006282]; regulation of DNA replication [GO:0006275]; regulation of DNA strand elongation [GO:0060382]; regulation of embryonic development [GO:0045995]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of transcription from RNA polymerase II promoter in response to stress [GO:0043618]; spindle assembly [GO:0051225]; telomere maintenance [GO:0000723]; UV-damage excision repair [GO:0070914] GO:0000070; GO:0000723; GO:0000724; GO:0003677; GO:0003779; GO:0005524; GO:0005634; GO:0005654; GO:0005819; GO:0005829; GO:0005874; GO:0006275; GO:0006281; GO:0006282; GO:0006302; GO:0006338; GO:0006351; GO:0008094; GO:0010571; GO:0016604; GO:0016887; GO:0030307; GO:0031011; GO:0033044; GO:0034644; GO:0042393; GO:0043014; GO:0043618; GO:0045739; GO:0045893; GO:0045944; GO:0045995; GO:0051225; GO:0051301; GO:0051726; GO:0060382; GO:0070914; GO:0071479; GO:0140658; GO:1904507; GO:2000045 15693 XM_044306931.1 2 0 12 7 13 NA NA NA NA NA NA 15694 XR_006396601.1 44 39 29 45 89 NA NA NA NA NA NA 15695 XM_044314080.1 35 28 16 16 41 NA NA NA NA NA NA 15696 XM_044319703.1 24 20 19 19 28 E7FAM5 1.02e-90 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 15697 XM_044307503.1 355 1024 771 1953 667 Q6DFF6 2.02e-28 Kelch-like protein 20 Xenopus laevis (African clawed frog) Golgi to endosome transport [GO:0006895]; negative regulation of apoptotic process [GO:0043066]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K33-linked ubiquitination [GO:1990390]; protein transport [GO:0015031]; protein ubiquitination [GO:0016567] GO:0004842; GO:0005737; GO:0005802; GO:0005829; GO:0006895; GO:0015031; GO:0016567; GO:0016605; GO:0019964; GO:0031463; GO:0043066; GO:0043161; GO:0048471; GO:1990390 15698 XM_029347238.2 1523 1409 689 1348 1225 P35286 2.03e-74 Ras-related protein Rab-13 Rattus norvegicus (Rat) bicellular tight junction assembly [GO:0070830]; cellular response to insulin stimulus [GO:0032869]; cortical actin cytoskeleton organization [GO:0030866]; endocytic recycling [GO:0032456]; endosomal transport [GO:0016197]; endothelial cell chemotaxis [GO:0035767]; establishment of Sertoli cell barrier [GO:0097368]; glucose homeostasis [GO:0042593]; Golgi vesicle fusion to target membrane [GO:0048210]; neuron projection development [GO:0031175]; positive regulation of glucose import [GO:0046326]; protein kinase A signaling [GO:0010737]; protein localization to cell leading edge [GO:1902463]; protein localization to plasma membrane [GO:0072659]; protein secretion [GO:0009306]; regulation of exocytosis [GO:0017157]; trans-Golgi network to recycling endosome transport [GO:0044795]; vesicle docking involved in exocytosis [GO:0006904] GO:0003924; GO:0005525; GO:0005768; GO:0005794; GO:0005802; GO:0005886; GO:0005911; GO:0005923; GO:0006904; GO:0008021; GO:0009306; GO:0010737; GO:0016197; GO:0016328; GO:0017157; GO:0030027; GO:0030139; GO:0030140; GO:0030659; GO:0030866; GO:0031175; GO:0031410; GO:0032456; GO:0032593; GO:0032869; GO:0034236; GO:0035767; GO:0042593; GO:0043005; GO:0043231; GO:0044795; GO:0046326; GO:0048210; GO:0055037; GO:0055038; GO:0070830; GO:0072659; GO:0097368; GO:1902463 15699 XM_029349526.2 29 31 30 63 27 Q9Y394 7.03e-73 Dehydrogenase/reductase SDR family member 7 (EC 1.1.1.-) (Retinal short-chain dehydrogenase/reductase 4) (retSDR4) (Short chain dehydrogenase/reductase family 34C member 1) (Protein SDR34C1) Homo sapiens (Human) NA GO:0004090; GO:0005789; GO:0016020; GO:0016616; GO:0052650 15700 XM_044308504.1 1215 148 319 58 336 NA NA NA NA NA NA 15701 XM_044307815.1 0 34 18 5 8 NA NA NA NA NA NA 15702 XM_029346370.2 2114 2301 1023 2161 486 NA NA NA NA NA NA 15703 XM_029329353.2 125 0 0 345 560 O08873 8.83e-159 MAP kinase-activating death domain protein (Rab3 GDP/GTP exchange factor) (RabGEF) (Rab3 GDP/GTP exchange protein) (RabGEP) Rattus norvegicus (Rat) anterograde synaptic vesicle transport [GO:0048490]; execution phase of apoptosis [GO:0097194]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of growth hormone secretion [GO:0060125]; negative regulation of pancreatic amylase secretion [GO:1902277]; positive regulation of MAPK cascade [GO:0043410]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of extrinsic apoptotic signaling pathway [GO:2001236]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of Rab protein signal transduction [GO:0032483] GO:0005085; GO:0005634; GO:0005829; GO:0005886; GO:0008021; GO:0016020; GO:0030424; GO:0032483; GO:0042981; GO:0043410; GO:0045202; GO:0048490; GO:0051726; GO:0060125; GO:0097194; GO:1902041; GO:1902277; GO:1904115; GO:2001234; GO:2001236 15704 XM_029329353.2 125 0 0 345 560 O08873 1.25e-123 MAP kinase-activating death domain protein (Rab3 GDP/GTP exchange factor) (RabGEF) (Rab3 GDP/GTP exchange protein) (RabGEP) Rattus norvegicus (Rat) anterograde synaptic vesicle transport [GO:0048490]; execution phase of apoptosis [GO:0097194]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of growth hormone secretion [GO:0060125]; negative regulation of pancreatic amylase secretion [GO:1902277]; positive regulation of MAPK cascade [GO:0043410]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of extrinsic apoptotic signaling pathway [GO:2001236]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of Rab protein signal transduction [GO:0032483] GO:0005085; GO:0005634; GO:0005829; GO:0005886; GO:0008021; GO:0016020; GO:0030424; GO:0032483; GO:0042981; GO:0043410; GO:0045202; GO:0048490; GO:0051726; GO:0060125; GO:0097194; GO:1902041; GO:1902277; GO:1904115; GO:2001234; GO:2001236 15705 XM_044326349.1 1488 2826 1693 1448 109 R1CW23 1.57e-109 Dimethylsulfonioproprionate lyase 7 (DMSP lyase 7) (EC 4.4.1.3) (Dimethylpropiothetin dethiomethylase 7) Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi) NA GO:0047869 15706 XM_029349109.2 877 396 517 882 461 Q16698 2.19e-130 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial (EC 1.3.1.124) (2,4-dienoyl-CoA reductase [NADPH]) (4-enoyl-CoA reductase [NADPH]) (Short chain dehydrogenase/reductase family 18C member 1) Homo sapiens (Human) fatty acid beta-oxidation [GO:0006635]; positive regulation of cold-induced thermogenesis [GO:0120162] GO:0005634; GO:0005654; GO:0005739; GO:0005759; GO:0005829; GO:0006635; GO:0008670; GO:0042802; GO:0070402; GO:0120162; GO:1902494 15707 XM_044322248.1 58 0 35 80 0 Q9NR16 8.84e-67 Scavenger receptor cysteine-rich type 1 protein M160 (CD163 antigen-like 1) (CD antigen CD163b) Homo sapiens (Human) NA GO:0005044; GO:0005576; GO:0009897 15708 XM_044322248.1 58 0 35 80 0 Q9NR16 2.13e-55 Scavenger receptor cysteine-rich type 1 protein M160 (CD163 antigen-like 1) (CD antigen CD163b) Homo sapiens (Human) NA GO:0005044; GO:0005576; GO:0009897 15709 XM_044322248.1 58 0 35 80 0 Q9NR16 4.38e-49 Scavenger receptor cysteine-rich type 1 protein M160 (CD163 antigen-like 1) (CD antigen CD163b) Homo sapiens (Human) NA GO:0005044; GO:0005576; GO:0009897 15710 XM_044322248.1 58 0 35 80 0 Q9NR16 1.62e-34 Scavenger receptor cysteine-rich type 1 protein M160 (CD163 antigen-like 1) (CD antigen CD163b) Homo sapiens (Human) NA GO:0005044; GO:0005576; GO:0009897 15711 XM_044322248.1 58 0 35 80 0 Q9NR16 1.88e-27 Scavenger receptor cysteine-rich type 1 protein M160 (CD163 antigen-like 1) (CD antigen CD163b) Homo sapiens (Human) NA GO:0005044; GO:0005576; GO:0009897 15712 XR_003825698.2 188 78 84 161 122 NA NA NA NA NA NA 15713 XM_044325364.1 31 0 0 9 5 NA NA NA NA NA NA 15714 XR_006391839.1 48 0 42 20 0 NA NA NA NA NA NA 15715 XM_029350435.2 185 78 51 242 75 NA NA NA NA NA NA 15716 XR_006397269.1 10 6 13 3 4 NA NA NA NA NA NA 15717 XM_029346611.2 35 13 50 45 65 P13608 4.39e-25 Aggrecan core protein (Cartilage-specific proteoglycan core protein) (CSPCP) Bos taurus (Bovine) cell adhesion [GO:0007155]; central nervous system development [GO:0007417]; skeletal system development [GO:0001501] GO:0001501; GO:0005509; GO:0005540; GO:0005576; GO:0007155; GO:0007417; GO:0030246; GO:0031012 15718 XM_029353242.2 274 107 0 0 42 Q680A5 2.85e-100 Ribose-phosphate pyrophosphokinase 4 (EC 2.7.6.1) (Phosphoribosyl pyrophosphate synthase 4) Arabidopsis thaliana (Mouse-ear cress) 5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; phosphorylation [GO:0016310]; purine nucleotide biosynthetic process [GO:0006164] GO:0000287; GO:0002189; GO:0004749; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006015; GO:0006164; GO:0009506; GO:0016301; GO:0016310 15719 XR_006392896.1 41 2 25 5 151 NA NA NA NA NA NA 15720 XM_029324981.2 0 28 0 42 0 NA NA NA NA NA NA 15721 XM_044328564.1 28 0 16 5 31 NA NA NA NA NA NA 15722 XM_044307706.1 0 11 1 0 4 Q6ITT3 3.19e-61 Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C (EC 2.4.1.145) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVc) (GnT-IVc) (N-acetylglucosaminyltransferase IVc) (UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVc) Sus scrofa (Pig) protein N-linked glycosylation [GO:0006487] GO:0000139; GO:0006487; GO:0008375; GO:0008454; GO:0046872 15723 XM_029329988.2 532 420 211 395 504 Q66KD5 4.31e-65 Inhibitor of growth protein 3 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) chromatin organization [GO:0006325]; histone modification [GO:0016570] GO:0000812; GO:0006325; GO:0016570; GO:0046872 15724 XM_029329988.2 532 420 211 395 504 Q66KD5 1.22e-35 Inhibitor of growth protein 3 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) chromatin organization [GO:0006325]; histone modification [GO:0016570] GO:0000812; GO:0006325; GO:0016570; GO:0046872 15725 XM_044313948.1 63 0 80 115 261 A2AIV2 0 Protein virilizer homolog Mus musculus (Mouse) mRNA alternative polyadenylation [GO:0110104]; mRNA methylation [GO:0080009]; mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006397; GO:0008380; GO:0016604; GO:0016607; GO:0036396; GO:0080009; GO:0110104 15726 XM_044313948.1 63 0 80 115 261 A2AIV2 9.91e-26 Protein virilizer homolog Mus musculus (Mouse) mRNA alternative polyadenylation [GO:0110104]; mRNA methylation [GO:0080009]; mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006397; GO:0008380; GO:0016604; GO:0016607; GO:0036396; GO:0080009; GO:0110104 15727 XM_044322278.1 950 717 501 712 701 O70475 0 UDP-glucose 6-dehydrogenase (UDP-Glc dehydrogenase) (UDP-GlcDH) (UDPGDH) (EC 1.1.1.22) Mus musculus (Mouse) carbohydrate metabolic process [GO:0005975]; chondroitin sulfate biosynthetic process [GO:0030206]; gastrulation with mouth forming second [GO:0001702]; glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; neuron development [GO:0048666]; protein hexamerization [GO:0034214]; UDP-glucuronate biosynthetic process [GO:0006065] GO:0001702; GO:0003979; GO:0005634; GO:0005654; GO:0005829; GO:0005975; GO:0006024; GO:0006065; GO:0015012; GO:0030206; GO:0034214; GO:0042802; GO:0048666; GO:0051287 15728 XM_029355774.2 49 2 24 15 6 NA NA NA NA NA NA 15729 XM_044321578.1 24 4 2 0 0 Q4UMH6 8.16e-25 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 15730 XM_044321578.1 24 4 2 0 0 Q4UMH6 7.44e-23 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 15731 XM_044316745.1 9 35 21 55 0 NA NA NA NA NA NA 15732 XM_044327464.1 502 373 360 363 493 E7F6T8 5.29e-49 Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.4.19.12) (Deubiquitinating enzyme 37) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37) Danio rerio (Zebrafish) (Brachydanio rerio) cell division [GO:0051301]; central nervous system morphogenesis [GO:0021551]; cranial skeletal system development [GO:1904888]; G1/S transition of mitotic cell cycle [GO:0000082]; protein deubiquitination [GO:0016579]; protein K11-linked deubiquitination [GO:0035871]; protein K48-linked deubiquitination [GO:0071108]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000082; GO:0004197; GO:0004843; GO:0005634; GO:0005829; GO:0006511; GO:0016579; GO:0021551; GO:0035871; GO:0051301; GO:0071108; GO:1904888 15733 XM_044326285.1 6 0 0 0 17 NA NA NA NA NA NA 15734 XM_044315657.1 23 2 4 40 7 NA NA NA NA NA NA 15735 XM_044311508.1 0 0 16 8 1 NA NA NA NA NA NA 15736 XM_044311454.1 1 0 36 34 3 NA NA NA NA NA NA 15737 XM_029348115.2 2070 2020 1835 2732 2915 NA NA NA NA NA NA 15738 XM_029330609.2 152 2 26 3 86 NA NA NA NA NA NA 15739 XM_029346773.2 196 151 35 100 138 Q8C9V1 6.52e-32 Carabin (TBC1 domain family member 10C) Mus musculus (Mouse) activation of GTPase activity [GO:0090630]; B cell activation [GO:0042113]; calcineurin-NFAT signaling cascade [GO:0033173]; ERK1 and ERK2 cascade [GO:0070371]; negative regulation of B cell activation [GO:0050869]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; retrograde transport, endosome to Golgi [GO:0042147] GO:0005096; GO:0005829; GO:0005886; GO:0031527; GO:0033173; GO:0042113; GO:0042147; GO:0050869; GO:0070371; GO:0070373; GO:0070885; GO:0090630 15740 XM_044322427.1 19 10 1 9 5 NA NA NA NA NA NA 15741 XM_029330331.2 326 232 267 147 200 NA NA NA NA NA NA 15742 XM_044325154.1 178 225 45 192 52 P70085 2.7e-95 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Oryzias latipes (Japanese rice fish) (Japanese killifish) hormone biosynthetic process [GO:0042446]; progesterone metabolic process [GO:0042448]; steroid biosynthetic process [GO:0006694] GO:0004508; GO:0005506; GO:0006694; GO:0016020; GO:0020037; GO:0042446; GO:0042448; GO:0047442 15743 XM_029357073.2 122 24 39 46 158 P97931 1.47e-108 Uracil-DNA glycosylase (UDG) (EC 3.2.2.27) Mus musculus (Mouse) base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]; DNA repair [GO:0006281]; isotype switching [GO:0045190]; negative regulation of apoptotic process [GO:0043066]; somatic hypermutation of immunoglobulin genes [GO:0016446]; somatic recombination of immunoglobulin gene segments [GO:0016447] GO:0003684; GO:0004844; GO:0005634; GO:0005654; GO:0005739; GO:0006281; GO:0006284; GO:0016446; GO:0016447; GO:0043024; GO:0043066; GO:0045190; GO:0097510 15744 XM_029358747.2 363 248 216 260 488 NA NA NA NA NA NA 15745 XR_006392678.1 48 10 34 16 141 NA NA NA NA NA NA 15746 XM_029343536.2 684 456 883 883 1188 A1A5F2 0 HEAT repeat-containing protein 5B Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) protein transport [GO:0015031] GO:0015031; GO:0030136 15747 XM_044321992.1 24 10 16 5 57 A2VDD2 2.51e-24 Dynein light chain Tctex-type 5-B (Tctex1 domain-containing protein 1-B) Xenopus laevis (African clawed frog) NA NA 15748 XR_006392160.1 91 140 42 4 273 NA NA NA NA NA NA 15749 XM_029332953.2 61 9 0 39 44 NA NA NA NA NA NA 15750 XM_029350584.2 60 115 69 99 80 Q298P4 0 cGMP-specific 3',5'-cyclic phosphodiesterase (EC 3.1.4.35) Drosophila pseudoobscura pseudoobscura (Fruit fly) cGMP metabolic process [GO:0046068]; signal transduction [GO:0007165] GO:0005886; GO:0007165; GO:0016020; GO:0046068; GO:0046872; GO:0047555 15751 XM_044307161.1 23 30 37 10 36 Q91ZQ5 1.24e-99 Retinoid isomerohydrolase (EC 3.1.1.64) (All-trans-retinyl-palmitate hydrolase) (Lutein isomerase) (Meso-zeaxanthin isomerase) (EC 5.3.3.22) (Retinal pigment epithelium-specific 65 kDa protein) (Retinol isomerase) Mus musculus (Mouse) cellular response to electrical stimulus [GO:0071257]; circadian rhythm [GO:0007623]; detection of light stimulus involved in visual perception [GO:0050908]; insulin receptor signaling pathway [GO:0008286]; neural retina development [GO:0003407]; regulation of gene expression [GO:0010468]; retina development in camera-type eye [GO:0060041]; retina homeostasis [GO:0001895]; retina morphogenesis in camera-type eye [GO:0060042]; retinal metabolic process [GO:0042574]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; visual perception [GO:0007601]; zeaxanthin biosynthetic process [GO:1901827] GO:0001523; GO:0001786; GO:0001895; GO:0003407; GO:0005634; GO:0005737; GO:0005789; GO:0005886; GO:0007601; GO:0007623; GO:0008286; GO:0010468; GO:0016020; GO:0016702; GO:0016853; GO:0031210; GO:0042572; GO:0042574; GO:0044297; GO:0046872; GO:0050251; GO:0050908; GO:0052884; GO:0052885; GO:0060041; GO:0060042; GO:0071257; GO:1901612; GO:1901827 15752 XM_044321809.1 6 0 1 10 84 NA NA NA NA NA NA 15753 XR_003822740.2 7 0 0 0 0 Q2VPA6 0 Helicase POLQ-like (EC 3.6.4.12) (Mus308-like helicase) (POLQ-like helicase) Mus musculus (Mouse) DNA double-strand break processing involved in repair via single-strand annealing [GO:0010792]; DNA metabolic process [GO:0006259]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via synthesis-dependent strand annealing [GO:0045003]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; rRNA processing [GO:0006364] GO:0000724; GO:0003677; GO:0005524; GO:0005634; GO:0006259; GO:0006364; GO:0010792; GO:0016887; GO:0017116; GO:0017117; GO:0045003; GO:0090734; GO:0097681; GO:1905168; GO:1990518 15754 XM_029331376.2 7 20 20 12 14 Q7TN88 1.91e-55 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 15755 XM_029331376.2 7 20 20 12 14 Q7TN88 5.37e-52 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 15756 XM_029337835.2 0 0 0 0 31 Q8BLA8 2.93e-93 Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Wasabi receptor) Mus musculus (Mouse) calcium ion transmembrane import into cytosol [GO:0097553]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cell surface receptor signaling pathway [GO:0007166]; cellular calcium ion homeostasis [GO:0006874]; cellular response to carbon dioxide [GO:0071244]; cellular response to cold [GO:0070417]; cellular response to heat [GO:0034605]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to organic substance [GO:0071310]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; positive regulation of anion transport [GO:1903793]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of sensory perception of pain [GO:1904058]; protein homotetramerization [GO:0051289]; regulation of blood circulation [GO:1903522]; regulation of neuronal action potential [GO:0098908]; response to cold [GO:0009409]; response to hydrogen peroxide [GO:0042542]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; sensory perception of pain [GO:0019233]; thermoception [GO:0050955]; urinary bladder smooth muscle contraction [GO:0014832] GO:0005216; GO:0005245; GO:0005262; GO:0005886; GO:0006816; GO:0006874; GO:0007166; GO:0009409; GO:0009410; GO:0010033; GO:0014070; GO:0014832; GO:0015267; GO:0015278; GO:0016020; GO:0016324; GO:0019233; GO:0030424; GO:0032421; GO:0034605; GO:0035774; GO:0042542; GO:0042802; GO:0048265; GO:0050955; GO:0050966; GO:0050968; GO:0050974; GO:0051289; GO:0070301; GO:0070417; GO:0070588; GO:0071244; GO:0071310; GO:0097553; GO:0097604; GO:0098908; GO:1903522; GO:1903793; GO:1904058; GO:1990760 15757 XM_044326184.1 34 26 65 94 210 P46461 1.41e-87 Vesicle-fusing ATPase 1 (EC 3.6.4.6) (N-ethylmaleimide-sensitive fusion protein 1) (NEM-sensitive fusion protein 1) (Protein comatose) (Vesicular-fusion protein NSF1) (dNsf-1) (NSF-1) Drosophila melanogaster (Fruit fly) autophagy [GO:0006914]; Golgi organization [GO:0007030]; Golgi to lysosome transport [GO:0090160]; Golgi to plasma membrane protein transport [GO:0043001]; intra-Golgi vesicle-mediated transport [GO:0006891]; neuromuscular synaptic transmission [GO:0007274]; neuron cellular homeostasis [GO:0070050]; neurotransmitter secretion [GO:0007269]; regulation of neuromuscular synaptic transmission [GO:1900073]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; SNARE complex disassembly [GO:0035494]; synaptic vesicle cycle [GO:0099504]; synaptic vesicle fusion to presynaptic active zone membrane [GO:0031629]; synaptic vesicle priming [GO:0016082] GO:0005524; GO:0005737; GO:0005795; GO:0006891; GO:0006914; GO:0007030; GO:0007269; GO:0007274; GO:0016082; GO:0016887; GO:0031594; GO:0031629; GO:0035494; GO:0043001; GO:0043195; GO:0046872; GO:0048172; GO:0070050; GO:0090160; GO:0098527; GO:0099504; GO:0099523; GO:1900073 15758 XM_044309101.1 370 480 396 632 1388 Q14974 1.46e-167 Importin subunit beta-1 (Importin-90) (Karyopherin subunit beta-1) (Nuclear factor p97) (Pore targeting complex 97 kDa subunit) (PTAC97) Homo sapiens (Human) astral microtubule organization [GO:0030953]; establishment of mitotic spindle localization [GO:0040001]; establishment of protein localization [GO:0045184]; mitotic chromosome movement towards spindle pole [GO:0007079]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly [GO:0090307]; NLS-bearing protein import into nucleus [GO:0006607]; protein import into nucleus [GO:0006606]; Ran protein signal transduction [GO:0031291]; ribosomal protein import into nucleus [GO:0006610]; RNA import into nucleus [GO:0006404] GO:0003723; GO:0005576; GO:0005634; GO:0005635; GO:0005643; GO:0005654; GO:0005737; GO:0005829; GO:0006404; GO:0006606; GO:0006607; GO:0006610; GO:0007079; GO:0007080; GO:0008139; GO:0008270; GO:0010494; GO:0016020; GO:0019899; GO:0019904; GO:0030953; GO:0031267; GO:0031291; GO:0031965; GO:0035580; GO:0040001; GO:0042564; GO:0045184; GO:0051879; GO:0061608; GO:0061676; GO:0070062; GO:0071782; GO:0090307; GO:1904813 15759 XM_029335669.2 2348 3102 1604 1625 1139 Q8TDN4 3.54e-70 CDK5 and ABL1 enzyme substrate 1 (Interactor with CDK3 1) (Ik3-1) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; nervous system development [GO:0007399]; regulation of cell cycle [GO:0051726] GO:0005634; GO:0005829; GO:0007049; GO:0007399; GO:0051301; GO:0051726 15760 XM_029356650.2 16461 25646 19021 17459 11186 A8YXY3 6.37e-47 Selenoprotein F Bos taurus (Bovine) NA GO:0005788; GO:0016491 15761 XM_029358655.2 95 0 0 24 0 Q71B07 0 Probable C-mannosyltransferase DPY19L3 (EC 2.4.1.-) (Dpy-19-like protein 3) (Protein dpy-19 homolog 3) Mus musculus (Mouse) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan [GO:0018406] GO:0000030; GO:0005637; GO:0018406 15762 XM_029351542.2 1432 885 641 690 370 O00255 2.41e-120 Menin Homo sapiens (Human) brain development [GO:0007420]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to glucose stimulus [GO:0071333]; cellular response to peptide hormone stimulus [GO:0071375]; chromatin organization [GO:0006325]; decidualization [GO:0046697]; DNA repair [GO:0006281]; histone H3-K4 methylation [GO:0051568]; MAPK cascade [GO:0000165]; mitotic cell cycle [GO:0000278]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell cycle G1/S phase transition [GO:1902807]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of JNK cascade [GO:0046329]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; osteoblast development [GO:0002076]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of type B pancreatic cell proliferation [GO:0061469]; response to gamma radiation [GO:0010332]; response to transforming growth factor beta [GO:0071559]; response to UV [GO:0009411]; T-helper 2 cell differentiation [GO:0045064]; type B pancreatic cell differentiation [GO:0003309] GO:0000122; GO:0000165; GO:0000278; GO:0000400; GO:0000403; GO:0000781; GO:0000785; GO:0000976; GO:0001933; GO:0002076; GO:0003309; GO:0003682; GO:0003690; GO:0005634; GO:0005654; GO:0005737; GO:0005788; GO:0005829; GO:0006281; GO:0006325; GO:0006357; GO:0006974; GO:0007420; GO:0008285; GO:0009411; GO:0010332; GO:0010812; GO:0016363; GO:0017053; GO:0030511; GO:0030674; GO:0032154; GO:0032925; GO:0032991; GO:0035097; GO:0043433; GO:0044665; GO:0045064; GO:0045668; GO:0045736; GO:0045786; GO:0045892; GO:0045944; GO:0046329; GO:0046697; GO:0047485; GO:0050680; GO:0051219; GO:0051568; GO:0051974; GO:0061469; GO:0070412; GO:0071333; GO:0071339; GO:0071375; GO:0071559; GO:1902807 15763 XM_029341599.2 2655 2097 1404 1864 1419 Q6P2Y1 1.26e-126 RNA polymerase II-associated factor 1 homolog Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) histone modification [GO:0016570]; negative regulation of transcription by RNA polymerase II [GO:0000122]; transcription elongation by RNA polymerase II promoter [GO:0006368] GO:0000122; GO:0000993; GO:0006368; GO:0016570; GO:0016593 15764 XM_044328659.1 34 2 51 9 141 Q5HZL1 1.75e-90 ERI1 exoribonuclease 2 (EC 3.1.-.-) (Exonuclease domain-containing protein 1) Xenopus laevis (African clawed frog) NA GO:0003676; GO:0004527; GO:0008270 15765 XM_044308551.1 125 83 81 150 113 Q19425 6.81e-131 Sodium-coupled neutral amino acid transporter 9 homolog Caenorhabditis elegans amino acid transmembrane transport [GO:0003333] GO:0003333; GO:0005765; GO:0015179; GO:0031902; GO:0046872 15766 XM_029337294.2 1562 1292 917 1471 1707 Q9D8W5 0 26S proteasome non-ATPase regulatory subunit 12 (26S proteasome regulatory subunit RPN5) (26S proteasome regulatory subunit p55) Mus musculus (Mouse) NA GO:0000502; GO:0005737; GO:0005838; GO:0008541; GO:0022624 15767 XM_029340204.2 209 130 85 216 119 NA NA NA NA NA NA 15768 XR_006396616.1 0 0 16 3 1 NA NA NA NA NA NA 15769 XM_029323475.2 784 789 785 1102 1390 Q86W92 1.22e-103 Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2) Homo sapiens (Human) cell adhesion [GO:0007155]; neuromuscular junction development [GO:0007528]; synapse organization [GO:0050808] GO:0005829; GO:0005886; GO:0005925; GO:0007155; GO:0007528; GO:0045296; GO:0048786; GO:0050808 15770 XM_029323475.2 784 789 785 1102 1390 Q86W92 1.56e-27 Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2) Homo sapiens (Human) cell adhesion [GO:0007155]; neuromuscular junction development [GO:0007528]; synapse organization [GO:0050808] GO:0005829; GO:0005886; GO:0005925; GO:0007155; GO:0007528; GO:0045296; GO:0048786; GO:0050808 15771 XM_044329007.1 81 81 44 106 50 E3SCZ8 3.78e-37 Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) Cavia porcellus (Guinea pig) apoptotic process [GO:0006915]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; meiosis I [GO:0007127]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of apoptotic process [GO:0043066]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of peptidase activity [GO:0010466]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; regulation of mitotic cell cycle [GO:0007346]; regulation of type B pancreatic cell proliferation [GO:0061469]; sensory perception of sound [GO:0007605] GO:0000226; GO:0000775; GO:0000776; GO:0004869; GO:0005634; GO:0005737; GO:0005874; GO:0006915; GO:0007059; GO:0007127; GO:0007346; GO:0007605; GO:0010466; GO:0030496; GO:0043066; GO:0043524; GO:0046872; GO:0051233; GO:0051301; GO:0061178; GO:0061469 15772 XM_029350254.2 0 36 29 25 63 NA NA NA NA NA NA 15773 XM_029346016.2 0 1552 632 0 810 Q9I8X3 4.06e-72 Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) Danio rerio (Zebrafish) (Brachydanio rerio) apoptotic process [GO:0006915]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; regulation of hematopoietic stem cell differentiation [GO:1902036]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0004714; GO:0005007; GO:0005524; GO:0005886; GO:0006915; GO:0007169; GO:0008284; GO:0017134; GO:0033674; GO:0043235; GO:0043410; GO:1902036 15774 XR_003825488.2 31 28 36 44 55 NA NA NA NA NA NA 15775 XM_029338886.2 510 252 520 859 66 NA NA NA NA NA NA 15776 XM_029332808.2 218 134 49 0 0 NA NA NA NA NA NA 15777 XM_029353041.2 62 15 26 26 20 NA NA NA NA NA NA 15778 XR_006392500.1 178 200 180 21 757 NA NA NA NA NA NA 15779 XR_006396218.1 37 8 25 107 12 P10090 4.25e-157 Protein white (EC 7.6.2.-) (EC 7.6.2.6) (ATP-binding cassette transporter sub-family G member white) (Broad substrate specificity ATP-binding cassette transporter white) Drosophila melanogaster (Fruit fly) aminergic neurotransmitter loading into synaptic vesicle [GO:0015842]; biogenic amine biosynthetic process [GO:0042401]; cGMP transport [GO:0070731]; compound eye pigmentation [GO:0048072]; eye pigment metabolic process [GO:0042441]; eye pigment precursor transport [GO:0006856]; gravitaxis [GO:0042332]; guanine transport [GO:0015854]; histamine uptake [GO:0051615]; male courtship behavior [GO:0008049]; memory [GO:0007613]; ommochrome biosynthetic process [GO:0006727]; riboflavin transport [GO:0032218]; transmembrane transport [GO:0055085]; tryptophan transport [GO:0015827]; xanthine transport [GO:0042906] GO:0005275; GO:0005524; GO:0005886; GO:0006727; GO:0006856; GO:0007613; GO:0008049; GO:0008558; GO:0015196; GO:0015208; GO:0015827; GO:0015842; GO:0015854; GO:0016020; GO:0016887; GO:0022857; GO:0030659; GO:0031409; GO:0031410; GO:0032217; GO:0032218; GO:0042332; GO:0042401; GO:0042441; GO:0042626; GO:0042906; GO:0042907; GO:0048072; GO:0048770; GO:0051615; GO:0055085; GO:0070731; GO:0090741; GO:0098793; GO:1905948 15780 XM_029346115.2 0 0 199 0 124 Q3UJK4 0 GTP-binding protein 2 (GTP-binding-like protein 2) Mus musculus (Mouse) nuclear-transcribed mRNA catabolic process, no-go decay [GO:0070966]; rescue of stalled ribosome [GO:0072344]; translational elongation [GO:0006414] GO:0003746; GO:0003924; GO:0005525; GO:0006414; GO:0042802; GO:0070966; GO:0072344 15781 XM_044325089.1 0 0 0 0 7 Q55GU0 1.15e-24 Probable serine/threonine-protein kinase DDB_G0267514 (EC 2.7.11.1) Dictyostelium discoideum (Social amoeba) protein phosphorylation [GO:0006468]; signal transduction [GO:0007165] GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0006468; GO:0007165; GO:0106310 15782 XM_044315496.1 931 1730 1188 1481 949 NA NA NA NA NA NA 15783 XM_029341542.2 306 210 142 197 227 NA NA NA NA NA NA 15784 XR_006395036.1 0 0 0 5 45 NA NA NA NA NA NA 15785 XM_029355510.2 13 0 46 23 42 NA NA NA NA NA NA 15786 XM_044317374.1 0 0 0 0 23 Q7Z020 3.45e-134 Transient receptor potential cation channel subfamily A member 1 (dTRPA1) (Ankyrin-like with transmembrane domains protein 1) (dANKTM1) Drosophila melanogaster (Fruit fly) calcium ion transport [GO:0006816]; cation transport [GO:0006812]; cellular response to heat [GO:0034605]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; detection of temperature stimulus involved in thermoception [GO:0050960]; mechanosensory behavior [GO:0007638]; negative phototaxis [GO:0046957]; neuronal signal transduction [GO:0023041]; phototransduction [GO:0007602]; positive regulation of calcium-mediated signaling [GO:0050850]; response to heat [GO:0009408]; response to light stimulus [GO:0009416]; temperature compensation of the circadian clock [GO:0010378]; thermosensory behavior [GO:0040040]; thermotaxis [GO:0043052] GO:0001580; GO:0005261; GO:0005262; GO:0005886; GO:0006812; GO:0006816; GO:0007602; GO:0007638; GO:0009408; GO:0009416; GO:0010378; GO:0015276; GO:0016020; GO:0023041; GO:0034605; GO:0034703; GO:0040040; GO:0043052; GO:0046957; GO:0050850; GO:0050960; GO:0050965; GO:0050968; GO:0097604 15787 XM_044307553.1 4 7 17 13 0 NA NA NA NA NA NA 15788 XM_044324492.1 24 21 43 56 87 Q7PCJ9 1.89e-37 Thialysine N-epsilon-acetyltransferase (EC 2.3.1.-) (Diamine acetyltransferase 2) (EC 2.3.1.57) (Spermidine/spermine N(1)-acetyltransferase 2) (SSAT-2) Sus scrofa (Pig) spermidine acetylation [GO:0032918] GO:0004145; GO:0005737; GO:0008080; GO:0019809; GO:0032918 15789 XM_029341264.2 1 0 0 4 31 O16025 3.23e-46 Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (AOS) (EC 4.2.1.-) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)] Plexaura homomalla (Black sea rod) arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; lipid oxidation [GO:0034440]; oxylipin biosynthetic process [GO:0031408] GO:0005506; GO:0005737; GO:0006633; GO:0009978; GO:0016020; GO:0019369; GO:0020037; GO:0031408; GO:0034440; GO:0047677 15790 XM_029347081.2 123 143 67 139 181 NA NA NA NA NA NA 15791 XM_044308894.1 0 0 0 0 33 Q12955 7.06e-92 Ankyrin-3 (ANK-3) (Ankyrin-G) Homo sapiens (Human) axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165] GO:0000281; GO:0005200; GO:0005764; GO:0005783; GO:0005794; GO:0005829; GO:0005886; GO:0007009; GO:0007165; GO:0007409; GO:0007528; GO:0008092; GO:0008093; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014704; GO:0014731; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030425; GO:0030507; GO:0030674; GO:0031594; GO:0033268; GO:0034112; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045184; GO:0045211; GO:0045296; GO:0045838; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:1900827; GO:1902260; GO:2000651; GO:2001259 15792 XM_044308894.1 0 0 0 0 33 Q12955 9.5e-77 Ankyrin-3 (ANK-3) (Ankyrin-G) Homo sapiens (Human) axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165] GO:0000281; GO:0005200; GO:0005764; GO:0005783; GO:0005794; GO:0005829; GO:0005886; GO:0007009; GO:0007165; GO:0007409; GO:0007528; GO:0008092; GO:0008093; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014704; GO:0014731; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030425; GO:0030507; GO:0030674; GO:0031594; GO:0033268; GO:0034112; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045184; GO:0045211; GO:0045296; GO:0045838; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:1900827; GO:1902260; GO:2000651; GO:2001259 15793 XM_044308894.1 0 0 0 0 33 Q12955 2.73e-76 Ankyrin-3 (ANK-3) (Ankyrin-G) Homo sapiens (Human) axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165] GO:0000281; GO:0005200; GO:0005764; GO:0005783; GO:0005794; GO:0005829; GO:0005886; GO:0007009; GO:0007165; GO:0007409; GO:0007528; GO:0008092; GO:0008093; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014704; GO:0014731; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030425; GO:0030507; GO:0030674; GO:0031594; GO:0033268; GO:0034112; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045184; GO:0045211; GO:0045296; GO:0045838; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:1900827; GO:1902260; GO:2000651; GO:2001259 15794 XM_044308894.1 0 0 0 0 33 Q12955 9.16e-63 Ankyrin-3 (ANK-3) (Ankyrin-G) Homo sapiens (Human) axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165] GO:0000281; GO:0005200; GO:0005764; GO:0005783; GO:0005794; GO:0005829; GO:0005886; GO:0007009; GO:0007165; GO:0007409; GO:0007528; GO:0008092; GO:0008093; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014704; GO:0014731; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030425; GO:0030507; GO:0030674; GO:0031594; GO:0033268; GO:0034112; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045184; GO:0045211; GO:0045296; GO:0045838; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:1900827; GO:1902260; GO:2000651; GO:2001259 15795 XM_044308894.1 0 0 0 0 33 Q12955 1.5e-41 Ankyrin-3 (ANK-3) (Ankyrin-G) Homo sapiens (Human) axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165] GO:0000281; GO:0005200; GO:0005764; GO:0005783; GO:0005794; GO:0005829; GO:0005886; GO:0007009; GO:0007165; GO:0007409; GO:0007528; GO:0008092; GO:0008093; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014704; GO:0014731; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030425; GO:0030507; GO:0030674; GO:0031594; GO:0033268; GO:0034112; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045184; GO:0045211; GO:0045296; GO:0045838; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:1900827; GO:1902260; GO:2000651; GO:2001259 15796 XM_044315524.1 0 0 8 53 0 NA NA NA NA NA NA 15797 XM_044319007.1 17 13 4 0 0 Q9CZX5 1.57e-27 PIN2/TERF1-interacting telomerase inhibitor 1 (67-11-3 protein) (LPTS1) (Liver-related putative tumor suppressor) (Pin2-interacting protein X1) (TRF1-interacting protein 1) Mus musculus (Mouse) mitotic metaphase plate congression [GO:0007080]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; positive regulation of protein localization to nucleolus [GO:1904751]; positive regulation of telomeric DNA binding [GO:1904744]; protein localization to chromosome, telomeric region [GO:0070198]; protein localization to nucleolus [GO:1902570]; regulation of protein stability [GO:0031647]; ribosomal small subunit biogenesis [GO:0042274]; telomere maintenance via telomerase [GO:0007004] GO:0000228; GO:0000776; GO:0000781; GO:0005654; GO:0005730; GO:0005739; GO:0005819; GO:0007004; GO:0007080; GO:0010521; GO:0010972; GO:0031397; GO:0031647; GO:0032211; GO:0042274; GO:0044877; GO:0051974; GO:0070034; GO:0070198; GO:1902570; GO:1904744; GO:1904751 15798 XR_006395383.1 23 66 60 97 79 NA NA NA NA NA NA 15799 XM_044327696.1 6 20 0 15 80 NA NA NA NA NA NA 15800 XM_044309559.1 0 16 0 0 31 NA NA NA NA NA NA 15801 XM_044318651.1 21 36 21 27 48 Q9UBS5 3.37e-30 Gamma-aminobutyric acid type B receptor subunit 1 (GABA-B receptor 1) (GABA-B-R1) (GABA-BR1) (GABABR1) (Gb1) Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of dopamine secretion [GO:0033602]; negative regulation of epinephrine secretion [GO:0032811]; negative regulation of gamma-aminobutyric acid secretion [GO:0014053]; negative regulation of synaptic transmission [GO:0050805]; neuron-glial cell signaling [GO:0150099]; osteoblast differentiation [GO:0001649]; positive regulation of glutamate secretion [GO:0014049]; positive regulation of growth hormone secretion [GO:0060124]; response to ethanol [GO:0045471]; response to nicotine [GO:0035094]; synaptic transmission, GABAergic [GO:0051932] GO:0001649; GO:0004888; GO:0004965; GO:0005615; GO:0005789; GO:0005886; GO:0007193; GO:0007194; GO:0007214; GO:0008021; GO:0008285; GO:0014049; GO:0014053; GO:0030673; GO:0031966; GO:0032811; GO:0033602; GO:0035094; GO:0038039; GO:0042734; GO:0043025; GO:0043197; GO:0043198; GO:0045121; GO:0045211; GO:0045471; GO:0046982; GO:0050805; GO:0051932; GO:0060124; GO:0098685; GO:0098978; GO:0098982; GO:0099579; GO:0150047; GO:0150099; GO:1902712; GO:1990430 15802 XR_006392276.1 226 54 165 72 321 NA NA NA NA NA NA 15803 XM_029329655.2 868 512 535 684 952 Q5XPI3 1.04e-159 E3 ubiquitin-protein ligase RNF123 (EC 2.3.2.27) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123) (RING-type E3 ubiquitin transferase RNF123) Mus musculus (Mouse) proteolysis involved in protein catabolic process [GO:0051603] GO:0004842; GO:0005737; GO:0005829; GO:0031965; GO:0046872; GO:0051603 15804 XM_029329655.2 868 512 535 684 952 Q5XPI3 1.15e-130 E3 ubiquitin-protein ligase RNF123 (EC 2.3.2.27) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123) (RING-type E3 ubiquitin transferase RNF123) Mus musculus (Mouse) proteolysis involved in protein catabolic process [GO:0051603] GO:0004842; GO:0005737; GO:0005829; GO:0031965; GO:0046872; GO:0051603 15805 XM_044318641.1 256 124 69 224 243 Q7TNH6 3.57e-44 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 15806 XM_044318641.1 256 124 69 224 243 Q7TNH6 3.25e-43 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 15807 XM_044318641.1 256 124 69 224 243 Q7TNH6 7.86e-38 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 15808 XM_044325121.1 22 2 2 0 36 NA NA NA NA NA NA 15809 XM_044309884.1 0 18 7 19 32 Q7LHG5 1.26e-71 Transposon Ty3-I Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-2 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p52 (IN); Integrase p49 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 15810 XM_029344731.2 1222 568 608 1003 764 NA NA NA NA NA NA 15811 XR_006393219.1 349 553 788 79 46 NA NA NA NA NA NA 15812 XM_029336539.2 627 759 572 1143 1301 P30531 3.98e-152 Sodium- and chloride-dependent GABA transporter 1 (GAT-1) (Solute carrier family 6 member 1) Homo sapiens (Human) associative learning [GO:0008306]; chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid import [GO:0051939]; gamma-aminobutyric acid reuptake [GO:0051936]; inorganic anion import across plasma membrane [GO:0098658]; memory [GO:0007613]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; positive regulation of gamma-aminobutyric acid secretion [GO:0014054]; response to calcium ion [GO:0051592]; response to cocaine [GO:0042220]; response to estradiol [GO:0032355]; response to inorganic substance [GO:0010035]; response to lead ion [GO:0010288]; response to purine-containing compound [GO:0014074]; response to sucrose [GO:0009744]; response to toxic substance [GO:0009636]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725]; synapse organization [GO:0050808]; transport across blood-brain barrier [GO:0150104] GO:0005332; GO:0005886; GO:0007268; GO:0007613; GO:0008306; GO:0009636; GO:0009744; GO:0009986; GO:0010035; GO:0010288; GO:0014054; GO:0014074; GO:0015185; GO:0015378; GO:0016020; GO:0030424; GO:0032229; GO:0032355; GO:0035725; GO:0042220; GO:0042734; GO:0042802; GO:0043005; GO:0043025; GO:0045211; GO:0046872; GO:0050808; GO:0051592; GO:0051936; GO:0051939; GO:0098658; GO:0098719; GO:0098982; GO:0150104; GO:1902476 15813 XM_044328179.1 199 11 121 118 226 Q6GMF8 2.96e-156 Inactive rhomboid protein 1 (iRhom1) (Rhomboid family member 1) Danio rerio (Zebrafish) (Brachydanio rerio) cell migration [GO:0016477]; cell population proliferation [GO:0008283]; negative regulation of protein secretion [GO:0050709]; protein transport [GO:0015031]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of protein secretion [GO:0050708] GO:0000139; GO:0005789; GO:0008283; GO:0015031; GO:0016477; GO:0019838; GO:0042058; GO:0050708; GO:0050709; GO:0061136 15814 XM_044325670.1 4 24 53 34 44 NA NA NA NA NA NA 15815 XM_029358268.2 205 171 125 166 252 Q7TN88 6.52e-58 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 15816 XM_029358268.2 205 171 125 166 252 Q7TN88 2.04e-39 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 15817 XM_029346617.2 1870 1819 1172 2012 2676 Q4R8N7 0 Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0005634; GO:0120293 15818 XM_029346617.2 1870 1819 1172 2012 2676 Q4R8N7 9.6e-26 Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0005634; GO:0120293 15819 XM_029346617.2 1870 1819 1172 2012 2676 Q4R8N7 7.58e-24 Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0005634; GO:0120293 15820 XR_006396440.1 38 49 10 66 0 NA NA NA NA NA NA 15821 XR_006396186.1 411 286 572 679 470 NA NA NA NA NA NA 15822 XR_006396241.1 47 0 31 0 0 NA NA NA NA NA NA 15823 XM_029349385.2 143 458 103 161 280 Q9CZ04 1.49e-67 COP9 signalosome complex subunit 7a (SGN7a) (Signalosome subunit 7a) (JAB1-containing signalosome subunit 7a) Mus musculus (Mouse) COP9 signalosome assembly [GO:0010387]; protein deneddylation [GO:0000338] GO:0000338; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0008180; GO:0010387 15824 XM_029349247.2 603 479 186 598 422 Q1LY77 2.48e-95 Histone-lysine N-methyltransferase SETD1B-A (EC 2.1.1.354) (SET domain-containing protein 1B-A) Danio rerio (Zebrafish) (Brachydanio rerio) chromatin organization [GO:0006325]; hematopoietic progenitor cell differentiation [GO:0002244]; histone H3-K4 methylation [GO:0051568] GO:0002244; GO:0003723; GO:0005694; GO:0006325; GO:0016607; GO:0042800; GO:0048188; GO:0051568 15825 XM_029349247.2 603 479 186 598 422 Q1LY77 1.03e-31 Histone-lysine N-methyltransferase SETD1B-A (EC 2.1.1.354) (SET domain-containing protein 1B-A) Danio rerio (Zebrafish) (Brachydanio rerio) chromatin organization [GO:0006325]; hematopoietic progenitor cell differentiation [GO:0002244]; histone H3-K4 methylation [GO:0051568] GO:0002244; GO:0003723; GO:0005694; GO:0006325; GO:0016607; GO:0042800; GO:0048188; GO:0051568 15826 XM_029340539.2 615 206 285 469 423 Q8WUF5 4.98e-64 RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (NFkB-interacting protein 1) (PPP1R13B-like protein) Homo sapiens (Human) apoptotic process [GO:0006915]; cardiac muscle contraction [GO:0060048]; cardiac right ventricle morphogenesis [GO:0003215]; embryonic camera-type eye development [GO:0031076]; hair cycle [GO:0042633]; multicellular organism growth [GO:0035264]; multicellular organismal homeostasis [GO:0048871]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cell differentiation [GO:0045597]; post-embryonic development [GO:0009791]; regulation of transcription by RNA polymerase II [GO:0006357]; ventricular cardiac muscle tissue development [GO:0003229] GO:0000122; GO:0003215; GO:0003229; GO:0003714; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0006915; GO:0009791; GO:0030054; GO:0031076; GO:0035264; GO:0042633; GO:0042802; GO:0045171; GO:0045296; GO:0045597; GO:0048871; GO:0060048 15827 XM_044308355.1 24 0 2 0 1 NA NA NA NA NA NA 15828 XM_029342054.2 1 2 1574 1 0 Q60520 0 Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a) Mus musculus (Mouse) activation of innate immune response [GO:0002218]; aging [GO:0007568]; cellular response to dopamine [GO:1903351]; cellular response to glucose stimulus [GO:0071333]; cerebral cortex neuron differentiation [GO:0021895]; DNA replication [GO:0006260]; hematopoietic progenitor cell differentiation [GO:0002244]; histone deacetylation [GO:0016575]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell migration [GO:0030336]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of histone H3-K27 acetylation [GO:1901675]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of stem cell population maintenance [GO:1902455]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of heterochromatin formation [GO:0031453]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deacetylation [GO:0006476]; protein localization [GO:0008104]; regulation of axon extension [GO:0030516]; regulation of DNA-templated transcription [GO:0006355]; regulation of hormone levels [GO:0010817]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to methylglyoxal [GO:0051595]; response to organonitrogen compound [GO:0010243]; rhythmic process [GO:0048511] GO:0000118; GO:0000122; GO:0000776; GO:0000785; GO:0001701; GO:0002218; GO:0002230; GO:0002244; GO:0003677; GO:0003682; GO:0003713; GO:0003714; GO:0003723; GO:0005634; GO:0005654; GO:0005667; GO:0005730; GO:0006260; GO:0006355; GO:0006476; GO:0007568; GO:0008104; GO:0010243; GO:0010817; GO:0010971; GO:0016575; GO:0016580; GO:0017053; GO:0021895; GO:0030336; GO:0030512; GO:0030516; GO:0031453; GO:0032991; GO:0042754; GO:0043066; GO:0043619; GO:0044877; GO:0045666; GO:0045892; GO:0045944; GO:0048511; GO:0051595; GO:0061629; GO:0071333; GO:0140416; GO:1900181; GO:1901675; GO:1902455; GO:1902459; GO:1903351; GO:2000678 15829 XM_029342054.2 1 2 1574 1 0 Q60520 8.97e-39 Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a) Mus musculus (Mouse) activation of innate immune response [GO:0002218]; aging [GO:0007568]; cellular response to dopamine [GO:1903351]; cellular response to glucose stimulus [GO:0071333]; cerebral cortex neuron differentiation [GO:0021895]; DNA replication [GO:0006260]; hematopoietic progenitor cell differentiation [GO:0002244]; histone deacetylation [GO:0016575]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell migration [GO:0030336]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of histone H3-K27 acetylation [GO:1901675]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of stem cell population maintenance [GO:1902455]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of heterochromatin formation [GO:0031453]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deacetylation [GO:0006476]; protein localization [GO:0008104]; regulation of axon extension [GO:0030516]; regulation of DNA-templated transcription [GO:0006355]; regulation of hormone levels [GO:0010817]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to methylglyoxal [GO:0051595]; response to organonitrogen compound [GO:0010243]; rhythmic process [GO:0048511] GO:0000118; GO:0000122; GO:0000776; GO:0000785; GO:0001701; GO:0002218; GO:0002230; GO:0002244; GO:0003677; GO:0003682; GO:0003713; GO:0003714; GO:0003723; GO:0005634; GO:0005654; GO:0005667; GO:0005730; GO:0006260; GO:0006355; GO:0006476; GO:0007568; GO:0008104; GO:0010243; GO:0010817; GO:0010971; GO:0016575; GO:0016580; GO:0017053; GO:0021895; GO:0030336; GO:0030512; GO:0030516; GO:0031453; GO:0032991; GO:0042754; GO:0043066; GO:0043619; GO:0044877; GO:0045666; GO:0045892; GO:0045944; GO:0048511; GO:0051595; GO:0061629; GO:0071333; GO:0140416; GO:1900181; GO:1901675; GO:1902455; GO:1902459; GO:1903351; GO:2000678 15830 XM_029345461.2 912 679 539 765 804 Q5E9X1 1.69e-71 Nuclear transcription factor Y subunit gamma (CAAT box DNA-binding protein subunit C) (Nuclear transcription factor Y subunit C) (NF-YC) Bos taurus (Bovine) histone H3-K4 trimethylation [GO:0080182]; regulation of DNA-templated transcription [GO:0006355]; regulation of histone acetylation [GO:0035065] GO:0000978; GO:0001228; GO:0005634; GO:0005654; GO:0006355; GO:0016602; GO:0032993; GO:0035065; GO:0046982; GO:0080182 15831 XM_044317599.1 30 60 43 57 127 NA NA NA NA NA NA 15832 XM_029342424.2 768 877 477 902 729 A7SWH1 0 Pescadillo homolog Nematostella vectensis (Starlet sea anemone) maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000466]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463] GO:0000463; GO:0000466; GO:0003723; GO:0005654; GO:0030687; GO:0043021; GO:0070545 15833 XM_044319614.1 162 110 53 142 162 Q9DBQ7 4.26e-68 Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin-binding protein PACE-1) (SCY1-like protein 3) Mus musculus (Mouse) inflammatory response [GO:0006954]; neuron development [GO:0048666]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; spinal cord motor neuron differentiation [GO:0021522] GO:0000139; GO:0004672; GO:0005524; GO:0005737; GO:0005794; GO:0006468; GO:0006954; GO:0008104; GO:0021522; GO:0030027; GO:0042802; GO:0048666 15834 XM_029332538.2 899 1935 1367 837 778 NA NA NA NA NA NA 15835 XM_029351832.2 383 300 177 446 84 P23508 3.62e-95 Colorectal mutant cancer protein (Protein MCC) Homo sapiens (Human) establishment of protein localization [GO:0045184]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of epithelial cell proliferation [GO:0050680]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055] GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0007165; GO:0010633; GO:0016055; GO:0030027; GO:0036464; GO:0038023; GO:0045184; GO:0050680; GO:0090090 15836 XM_044327480.1 0 0 0 21 16 NA NA NA NA NA NA 15837 XR_006394724.1 17 9 3 49 47 NA NA NA NA NA NA 15838 XM_044316098.1 281 107 106 207 73 Q0P5F0 5.48e-89 Lysosomal acid phosphatase (LAP) (EC 3.1.3.2) Bos taurus (Bovine) dephosphorylation [GO:0016311]; lysosome organization [GO:0007040] GO:0003993; GO:0005764; GO:0005765; GO:0007040; GO:0016311; GO:0016791; GO:0043202 15839 XM_044314007.1 5 1 1 4 6 NA NA NA NA NA NA 15840 XM_044316895.1 60 0 0 53 53 P07314 3.35e-110 Glutathione hydrolase 1 proenzyme (EC 3.4.19.13) (Gamma-glutamyltransferase 1) (Gamma-glutamyltranspeptidase 1) (GGT 1) (EC 2.3.2.2) (Leukotriene-C4 hydrolase) (EC 3.4.19.14) (CD antigen CD224) [Cleaved into: Glutathione hydrolase 1 heavy chain; Glutathione hydrolase 1 light chain] Rattus norvegicus (Rat) aging [GO:0007568]; amino acid metabolic process [GO:0006520]; cellular response to oxidative stress [GO:0034599]; cysteine biosynthetic process [GO:0019344]; fatty acid metabolic process [GO:0006631]; glutamate metabolic process [GO:0006536]; glutathione biosynthetic process [GO:0006750]; glutathione catabolic process [GO:0006751]; hepatoblast differentiation [GO:0061017]; hepatocyte differentiation [GO:0070365]; leukotriene D4 biosynthetic process [GO:1901750]; leukotriene metabolic process [GO:0006691]; liver regeneration [GO:0097421]; peptide modification [GO:0031179]; proteolysis [GO:0006508]; regulation of immune system process [GO:0002682]; regulation of inflammatory response [GO:0050727]; response to alcohol [GO:0097305]; response to estradiol [GO:0032355]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]; spermatogenesis [GO:0007283]; zymogen activation [GO:0031638] GO:0000048; GO:0002682; GO:0002951; GO:0005615; GO:0005886; GO:0006508; GO:0006520; GO:0006536; GO:0006631; GO:0006691; GO:0006750; GO:0006751; GO:0007283; GO:0007568; GO:0016755; GO:0019344; GO:0031179; GO:0031638; GO:0031982; GO:0032355; GO:0032496; GO:0034599; GO:0034612; GO:0036374; GO:0050727; GO:0061017; GO:0070365; GO:0097305; GO:0097421; GO:0102953; GO:0103068; GO:1901750 15841 XM_029341883.2 35 1146 2156 3732 4882 A0A0G2K1Q8 0 Phospholipid-transporting ATPase ABCA3 (EC 7.6.2.1) (ATP-binding cassette sub-family A member 3) (Xenobiotic-transporting ATPase ABCA3) (EC 7.6.2.2) [Cleaved into: 150 Kda mature form] Rattus norvegicus (Rat) lipid transport [GO:0006869]; lung development [GO:0030324]; organelle assembly [GO:0070925]; phosphatidylcholine metabolic process [GO:0046470]; phosphatidylglycerol metabolic process [GO:0046471]; phospholipid homeostasis [GO:0055091]; phospholipid transport [GO:0015914]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of phospholipid efflux [GO:1902995]; positive regulation of phospholipid transport [GO:2001140]; positive regulation of protein homooligomerization [GO:0032464]; regulation of lipid biosynthetic process [GO:0046890]; regulation of lipid transport [GO:0032368]; regulation of phosphatidylcholine metabolic process [GO:0150172]; response to glucocorticoid [GO:0051384]; surfactant homeostasis [GO:0043129]; xenobiotic export from cell [GO:0046618]; xenobiotic transmembrane transport [GO:0006855]; xenobiotic transport [GO:0042908] GO:0005319; GO:0005524; GO:0005765; GO:0005770; GO:0005886; GO:0006855; GO:0006869; GO:0008559; GO:0010875; GO:0015914; GO:0016887; GO:0030324; GO:0030659; GO:0032368; GO:0032464; GO:0032585; GO:0042599; GO:0042626; GO:0042908; GO:0043129; GO:0043231; GO:0046470; GO:0046471; GO:0046618; GO:0046890; GO:0051384; GO:0055091; GO:0070925; GO:0097208; GO:0097232; GO:0097233; GO:0120019; GO:0140345; GO:0150172; GO:1902995; GO:2001140 15842 XM_029341883.2 35 1146 2156 3732 4882 A0A0G2K1Q8 1.47e-120 Phospholipid-transporting ATPase ABCA3 (EC 7.6.2.1) (ATP-binding cassette sub-family A member 3) (Xenobiotic-transporting ATPase ABCA3) (EC 7.6.2.2) [Cleaved into: 150 Kda mature form] Rattus norvegicus (Rat) lipid transport [GO:0006869]; lung development [GO:0030324]; organelle assembly [GO:0070925]; phosphatidylcholine metabolic process [GO:0046470]; phosphatidylglycerol metabolic process [GO:0046471]; phospholipid homeostasis [GO:0055091]; phospholipid transport [GO:0015914]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of phospholipid efflux [GO:1902995]; positive regulation of phospholipid transport [GO:2001140]; positive regulation of protein homooligomerization [GO:0032464]; regulation of lipid biosynthetic process [GO:0046890]; regulation of lipid transport [GO:0032368]; regulation of phosphatidylcholine metabolic process [GO:0150172]; response to glucocorticoid [GO:0051384]; surfactant homeostasis [GO:0043129]; xenobiotic export from cell [GO:0046618]; xenobiotic transmembrane transport [GO:0006855]; xenobiotic transport [GO:0042908] GO:0005319; GO:0005524; GO:0005765; GO:0005770; GO:0005886; GO:0006855; GO:0006869; GO:0008559; GO:0010875; GO:0015914; GO:0016887; GO:0030324; GO:0030659; GO:0032368; GO:0032464; GO:0032585; GO:0042599; GO:0042626; GO:0042908; GO:0043129; GO:0043231; GO:0046470; GO:0046471; GO:0046618; GO:0046890; GO:0051384; GO:0055091; GO:0070925; GO:0097208; GO:0097232; GO:0097233; GO:0120019; GO:0140345; GO:0150172; GO:1902995; GO:2001140 15843 XM_029341883.2 35 1146 2156 3732 4882 A0A0G2K1Q8 1.33e-48 Phospholipid-transporting ATPase ABCA3 (EC 7.6.2.1) (ATP-binding cassette sub-family A member 3) (Xenobiotic-transporting ATPase ABCA3) (EC 7.6.2.2) [Cleaved into: 150 Kda mature form] Rattus norvegicus (Rat) lipid transport [GO:0006869]; lung development [GO:0030324]; organelle assembly [GO:0070925]; phosphatidylcholine metabolic process [GO:0046470]; phosphatidylglycerol metabolic process [GO:0046471]; phospholipid homeostasis [GO:0055091]; phospholipid transport [GO:0015914]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of phospholipid efflux [GO:1902995]; positive regulation of phospholipid transport [GO:2001140]; positive regulation of protein homooligomerization [GO:0032464]; regulation of lipid biosynthetic process [GO:0046890]; regulation of lipid transport [GO:0032368]; regulation of phosphatidylcholine metabolic process [GO:0150172]; response to glucocorticoid [GO:0051384]; surfactant homeostasis [GO:0043129]; xenobiotic export from cell [GO:0046618]; xenobiotic transmembrane transport [GO:0006855]; xenobiotic transport [GO:0042908] GO:0005319; GO:0005524; GO:0005765; GO:0005770; GO:0005886; GO:0006855; GO:0006869; GO:0008559; GO:0010875; GO:0015914; GO:0016887; GO:0030324; GO:0030659; GO:0032368; GO:0032464; GO:0032585; GO:0042599; GO:0042626; GO:0042908; GO:0043129; GO:0043231; GO:0046470; GO:0046471; GO:0046618; GO:0046890; GO:0051384; GO:0055091; GO:0070925; GO:0097208; GO:0097232; GO:0097233; GO:0120019; GO:0140345; GO:0150172; GO:1902995; GO:2001140 15844 XM_029341883.2 35 1146 2156 3732 4882 A0A0G2K1Q8 1.83e-43 Phospholipid-transporting ATPase ABCA3 (EC 7.6.2.1) (ATP-binding cassette sub-family A member 3) (Xenobiotic-transporting ATPase ABCA3) (EC 7.6.2.2) [Cleaved into: 150 Kda mature form] Rattus norvegicus (Rat) lipid transport [GO:0006869]; lung development [GO:0030324]; organelle assembly [GO:0070925]; phosphatidylcholine metabolic process [GO:0046470]; phosphatidylglycerol metabolic process [GO:0046471]; phospholipid homeostasis [GO:0055091]; phospholipid transport [GO:0015914]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of phospholipid efflux [GO:1902995]; positive regulation of phospholipid transport [GO:2001140]; positive regulation of protein homooligomerization [GO:0032464]; regulation of lipid biosynthetic process [GO:0046890]; regulation of lipid transport [GO:0032368]; regulation of phosphatidylcholine metabolic process [GO:0150172]; response to glucocorticoid [GO:0051384]; surfactant homeostasis [GO:0043129]; xenobiotic export from cell [GO:0046618]; xenobiotic transmembrane transport [GO:0006855]; xenobiotic transport [GO:0042908] GO:0005319; GO:0005524; GO:0005765; GO:0005770; GO:0005886; GO:0006855; GO:0006869; GO:0008559; GO:0010875; GO:0015914; GO:0016887; GO:0030324; GO:0030659; GO:0032368; GO:0032464; GO:0032585; GO:0042599; GO:0042626; GO:0042908; GO:0043129; GO:0043231; GO:0046470; GO:0046471; GO:0046618; GO:0046890; GO:0051384; GO:0055091; GO:0070925; GO:0097208; GO:0097232; GO:0097233; GO:0120019; GO:0140345; GO:0150172; GO:1902995; GO:2001140 15845 XM_044328410.1 330 56 91 228 234 P70490 1.67e-39 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 15846 XM_044313840.1 0 0 0 0 8 NA NA NA NA NA NA 15847 XM_029352477.2 307 588 568 286 228 NA NA NA NA NA NA 15848 XM_044322126.1 100 51 22 48 33 Q5ZIJ0 7.28e-63 BUD13 homolog Gallus gallus (Chicken) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0005634; GO:0005684; GO:0070274; GO:0071005 15849 XM_029347631.2 1590 1051 228 857 624 NA NA NA NA NA NA 15850 XM_044316505.1 51 9 0 5 3 NA NA NA NA NA NA 15851 XM_029355957.2 2652 3070 1837 1357 518 Q5R971 2.62e-158 Delta-aminolevulinic acid dehydratase (ALADH) (EC 4.2.1.24) (Porphobilinogen synthase) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782] GO:0004655; GO:0006782; GO:0006783; GO:0008270 15852 XM_029349899.2 19302 21071 10552 16776 10439 Q4GXG7 8.02e-76 60S ribosomal protein L18 Timarcha balearica translation [GO:0006412] GO:0003735; GO:0005737; GO:0005840; GO:0006412; GO:1990904 15853 XR_006391389.1 4 74 0 0 0 NA NA NA NA NA NA 15854 XM_044315411.1 9 9 19 15 11 NA NA NA NA NA NA 15855 XM_029344437.2 736 560 389 367 177 NA NA NA NA NA NA 15856 XM_029346741.2 17 21 39 36 146 NA NA NA NA NA NA 15857 XM_044309037.1 6 0 0 6 5 NA NA NA NA NA NA 15858 XM_029342326.2 494 2870 1616 1139 275 NA NA NA NA NA NA 15859 XM_029334379.2 2506 1023 3 344 2641 B3EWY9 4.51e-41 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 15860 XM_029334379.2 2506 1023 3 344 2641 B3EWY9 1.26e-33 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 15861 XR_006392909.1 41 2 25 5 151 NA NA NA NA NA NA 15862 XR_006397268.1 106 239 182 89 168 NA NA NA NA NA NA 15863 XR_003827378.2 4024 4050 1467 2148 1716 NA NA NA NA NA NA 15864 XM_044322660.1 5 9 7 20 11 Q09575 9.62e-23 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 15865 XM_029353612.2 51 36 37 47 62 O95084 2.92e-37 Serine protease 23 (EC 3.4.21.-) (Putative secreted protein Zsig13) Homo sapiens (Human) proteolysis [GO:0006508] GO:0004252; GO:0005634; GO:0005788; GO:0006508; GO:0070062 15866 XM_044316965.1 1053 1114 483 877 1021 NA NA NA NA NA NA 15867 XM_029346341.2 118 208 135 201 112 Q07263 1.2e-87 Neuronal acetylcholine receptor subunit alpha-3 Bos taurus (Bovine) behavioral response to nicotine [GO:0035095]; chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; nervous system development [GO:0007399]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165]; synaptic transmission involved in micturition [GO:0060084] GO:0005231; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0007399; GO:0015464; GO:0022848; GO:0030594; GO:0034220; GO:0035095; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0060084; GO:1904315 15868 XR_006396852.1 17 0 0 51 42 NA NA NA NA NA NA 15869 XM_029332799.2 0 0 2 126 441 NA NA NA NA NA NA 15870 XM_044322991.1 814 426 476 586 671 Q9P0U3 5.2e-79 Sentrin-specific protease 1 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP1) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic signaling pathway [GO:0097190]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein desumoylation [GO:0016926]; protein sumoylation [GO:0016925]; proteolysis [GO:0006508] GO:0004175; GO:0005634; GO:0005654; GO:0005737; GO:0005925; GO:0006508; GO:0006919; GO:0016925; GO:0016926; GO:0016929; GO:0031965; GO:0045944; GO:0070139; GO:0097190 15871 XM_029335567.2 1062 948 710 610 1043 Q7ZVK4 5.93e-144 Vacuolar protein-sorting-associated protein 36 (ESCRT-II complex subunit VPS36) Danio rerio (Zebrafish) (Brachydanio rerio) anatomical structure development [GO:0048856]; protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328] GO:0000814; GO:0005768; GO:0031902; GO:0032266; GO:0043130; GO:0043328; GO:0048856 15872 XR_006392908.1 41 2 25 5 151 NA NA NA NA NA NA 15873 XM_044328018.1 1 0 1 11 10 Q6AYJ1 8.76e-41 ATP-dependent DNA helicase Q1 (EC 3.6.4.12) (DNA-dependent ATPase Q1) (RecQ protein-like 1) Rattus norvegicus (Rat) DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724] GO:0000724; GO:0003678; GO:0005524; GO:0005634; GO:0005694; GO:0005737; GO:0006268; GO:0006281; GO:0006310; GO:0009378; GO:0016887; GO:0032508; GO:0043138; GO:1990814 15874 XR_003824703.2 0 0 0 0 7 NA NA NA NA NA NA 15875 XM_029328942.2 129 172 190 182 195 Q921H9 6.15e-41 Cytochrome c oxidase assembly factor 7 (Beta-lactamase hcp-like protein) (Respiratory chain assembly factor 1) (Sel1 repeat-containing protein 1) Mus musculus (Mouse) NA GO:0005654; GO:0005739; GO:0005758 15876 XM_044322601.1 0 17 14 0 10 Q58L91 2.27e-28 Venom prothrombin activator oscutarin-C non-catalytic subunit (vPA) (Venom coagulation factor Va-like protein) [Cleaved into: Oscutarin-C non-catalytic subunit heavy chain; Oscutarin-C non-catalytic subunit light chain] Oxyuranus scutellatus (Coastal taipan) envenomation resulting in positive regulation of blood coagulation in another organism [GO:0044469]; positive regulation of blood coagulation in another organism [GO:0035807]; positive regulation of peptidase activity [GO:0010952] GO:0005507; GO:0005576; GO:0010952; GO:0016504; GO:0032991; GO:0035807; GO:0044469; GO:0090729 15877 XM_044311211.1 70 0 0 0 20 NA NA NA NA NA NA 15878 XM_029336250.2 0 0 13 20 77 F1PZV2 5.06e-21 Major facilitator superfamily domain-containing protein 12 Canis lupus familiaris (Dog) (Canis familiaris) carbohydrate transport [GO:0008643]; cysteine transmembrane transport [GO:1903712]; melanin biosynthetic process [GO:0042438]; organic substance transport [GO:0071702]; pigment metabolic process involved in pigmentation [GO:0043474]; regulation of melanin biosynthetic process [GO:0048021] GO:0005764; GO:0005765; GO:0005886; GO:0008643; GO:0015293; GO:0033162; GO:0033229; GO:0042438; GO:0043474; GO:0048021; GO:0071702; GO:1903712 15879 XM_044327644.1 431 542 121 311 326 NA NA NA NA NA NA 15880 XM_044325824.1 0 26 0 0 5 NA NA NA NA NA NA 15881 XM_044310294.1 1211 338 350 1564 1357 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15882 XM_044310294.1 1211 338 350 1564 1357 Q96AY4 2.09e-171 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15883 XM_044310294.1 1211 338 350 1564 1357 Q96AY4 5.67e-171 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15884 XM_044310294.1 1211 338 350 1564 1357 Q96AY4 8.55e-156 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15885 XM_044310294.1 1211 338 350 1564 1357 Q96AY4 2.51e-133 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15886 XM_044310294.1 1211 338 350 1564 1357 Q96AY4 1.12e-125 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15887 XM_044310294.1 1211 338 350 1564 1357 Q96AY4 2.38e-115 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15888 XM_029342260.2 2813 2715 1652 3419 2962 O00712 2.18e-96 Nuclear factor 1 B-type (NF1-B) (Nuclear factor 1/B) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/B) (NF-I/B) (NFI-B) (TGGCA-binding protein) Homo sapiens (Human) anterior commissure morphogenesis [GO:0021960]; brain development [GO:0007420]; cell differentiation involved in salivary gland development [GO:0060689]; chondrocyte differentiation [GO:0002062]; club cell differentiation [GO:0060486]; commissural neuron axon guidance [GO:0071679]; DNA replication [GO:0006260]; glandular epithelial cell differentiation [GO:0002067]; glial cell differentiation [GO:0010001]; hindbrain development [GO:0030902]; lung ciliated cell differentiation [GO:0061141]; negative regulation of DNA binding [GO:0043392]; negative regulation of epithelial cell proliferation involved in lung morphogenesis [GO:2000795]; negative regulation of mesenchymal cell proliferation involved in lung development [GO:2000791]; negative regulation of miRNA transcription [GO:1902894]; negative regulation of stem cell proliferation [GO:2000647]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; principal sensory nucleus of trigeminal nerve development [GO:0021740]; regulation of transcription by RNA polymerase II [GO:0006357]; response to bacterium [GO:0009617]; salivary gland cavitation [GO:0060662]; stem cell proliferation [GO:0072089]; type I pneumocyte differentiation [GO:0060509]; type II pneumocyte differentiation [GO:0060510] GO:0000122; GO:0000785; GO:0000978; GO:0000981; GO:0001228; GO:0001650; GO:0002062; GO:0002067; GO:0003677; GO:0005634; GO:0005654; GO:0006260; GO:0006357; GO:0007420; GO:0009617; GO:0010001; GO:0021740; GO:0021960; GO:0030902; GO:0043392; GO:0044300; GO:0045893; GO:0045944; GO:0060486; GO:0060509; GO:0060510; GO:0060662; GO:0060689; GO:0061141; GO:0071679; GO:0072089; GO:0140416; GO:1902894; GO:1990837; GO:2000647; GO:2000791; GO:2000795 15889 XR_006396279.1 32 75 27 16 74 NA NA NA NA NA NA 15890 XM_029325131.2 108 63 56 62 57 NA NA NA NA NA NA 15891 XM_044318905.1 23 16 65 73 160 NA NA NA NA NA NA 15892 XM_044308502.1 163 74 52 64 70 E7FAM5 1.48e-55 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 15893 XM_044308502.1 163 74 52 64 70 E7FAM5 1.69e-55 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 15894 XM_044322305.1 2 3 16 0 10 NA NA NA NA NA NA 15895 XM_029325672.2 0 1 0 1 31 NA NA NA NA NA NA 15896 XM_044310781.1 27 81 58 152 120 NA NA NA NA NA NA 15897 XM_029355917.2 402 261 144 193 256 Q8JGM4 1.31e-116 Sulfhydryl oxidase 1 (EC 1.8.3.2) (Quiescin Q6) Gallus gallus (Chicken) protein folding [GO:0006457] GO:0000139; GO:0003756; GO:0005615; GO:0006457; GO:0016971 15898 XM_029352749.2 733 1039 448 1435 728 Q27958 9.67e-155 DNA polymerase beta (EC 2.7.7.7) (EC 4.2.99.-) Bos taurus (Bovine) base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; DNA-templated DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303] GO:0003677; GO:0003887; GO:0005634; GO:0005737; GO:0006261; GO:0006284; GO:0006303; GO:0006974; GO:0016829; GO:0046872 15899 XM_029356120.2 13887 17053 12408 11233 8835 Q802G6 2.83e-38 Methionine-R-sulfoxide reductase B1-A (MsrB) (MsrB1-A) (EC 1.8.4.12) (EC 1.8.4.14) (Selenoprotein X-A) (SePR) (SelX-A) Danio rerio (Zebrafish) (Brachydanio rerio) actin filament polymerization [GO:0030041]; innate immune response [GO:0045087]; protein repair [GO:0030091] GO:0003779; GO:0005634; GO:0005737; GO:0005856; GO:0030041; GO:0030091; GO:0033743; GO:0033745; GO:0045087; GO:0046872; GO:0070191 15900 XR_003826506.2 35 46 132 24 135 Q86WA9 1.86e-53 Sodium-independent sulfate anion transporter (Solute carrier family 26 member 11) Homo sapiens (Human) ion transport [GO:0006811]; sulfate transport [GO:0008272] GO:0005654; GO:0005765; GO:0005783; GO:0005794; GO:0005886; GO:0006811; GO:0008271; GO:0008272; GO:0008509; GO:0015116; GO:0016020; GO:0043231; GO:0070062 15901 XR_003826506.2 35 46 132 24 135 Q86WA9 1.86e-53 Sodium-independent sulfate anion transporter (Solute carrier family 26 member 11) Homo sapiens (Human) ion transport [GO:0006811]; sulfate transport [GO:0008272] GO:0005654; GO:0005765; GO:0005783; GO:0005794; GO:0005886; GO:0006811; GO:0008271; GO:0008272; GO:0008509; GO:0015116; GO:0016020; GO:0043231; GO:0070062 15902 XM_029333463.2 440 408 424 270 364 Q9Y256 8.99e-71 CAAX prenyl protease 2 (EC 3.4.-.-) (Farnesylated proteins-converting enzyme 2) (FACE-2) (Prenyl protein-specific endoprotease 2) (RCE1 homolog) (hRCE1) Homo sapiens (Human) CAAX-box protein processing [GO:0071586]; MAPK cascade [GO:0000165]; protein prenylation [GO:0018342] GO:0000165; GO:0004175; GO:0004197; GO:0004222; GO:0005789; GO:0005829; GO:0005886; GO:0008238; GO:0016020; GO:0018342; GO:0071586 15903 XM_029339846.2 1389 1362 521 1847 1182 Q2VJ60 2.22e-156 E3 ubiquitin-protein ligase RNF19A (EC 2.3.2.31) (Double ring-finger protein) (Dorfin) (RING finger protein 19A) Sus scrofa (Pig) positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000151; GO:0000209; GO:0005737; GO:0005815; GO:0006511; GO:0016020; GO:0031624; GO:0032436; GO:0046872; GO:0061630; GO:0098686; GO:0098794; GO:0098978; GO:0099576 15904 XM_044316096.1 1302 190 1403 1262 565 NA NA NA NA NA NA 15905 XM_044310513.1 75 24 47 84 24 Q7RTR2 2.74e-63 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 15906 XM_044310513.1 75 24 47 84 24 Q7RTR2 3.48e-58 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 15907 XM_044310513.1 75 24 47 84 24 Q7RTR2 1.94e-42 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 15908 XM_044310513.1 75 24 47 84 24 Q7RTR2 3.22e-37 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 15909 XM_044328870.1 11 5 6 12 0 Q96AY4 1.12e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15910 XM_029336867.2 187 51 93 85 75 NA NA NA NA NA NA 15911 XM_044308926.1 35 188 57 28 686 NA NA NA NA NA NA 15912 XM_029357334.2 86 143 38 137 27 P22770 3.39e-72 Neuronal acetylcholine receptor subunit alpha-7 Gallus gallus (Chicken) calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; cognition [GO:0050890]; membrane depolarization [GO:0051899]; negative regulation of tumor necrosis factor production [GO:0032720]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAPK cascade [GO:0043410]; regulation of nitric oxide metabolic process [GO:0080164]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; signal transduction [GO:0007165] GO:0001540; GO:0001666; GO:0005737; GO:0005886; GO:0005892; GO:0006816; GO:0006874; GO:0007165; GO:0008284; GO:0015464; GO:0015643; GO:0017081; GO:0022848; GO:0030424; GO:0030425; GO:0032720; GO:0035094; GO:0042166; GO:0042803; GO:0043204; GO:0043410; GO:0045211; GO:0045766; GO:0050890; GO:0051899; GO:0080164 15913 XM_029354676.2 2545 2238 826 1469 949 O15992 0 Arginine kinase (AK) (EC 2.7.3.3) Anthopleura japonica (Sea anemone) phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310] GO:0004054; GO:0004111; GO:0005524; GO:0016310; GO:0046314 15914 XM_044306772.1 30 23 38 89 165 H1AFJ5 1.26e-38 Amiloride-sensitive sodium channel subunit alpha (Alpha-NaCH) (Epithelial Na(+) channel subunit alpha) (Alpha-ENaC) (Nonvoltage-gated sodium channel 1 subunit alpha) (SCNEA) Neoceratodus forsteri (Australian lungfish) (Ceratodus forsteri) sodium ion transmembrane transport [GO:0035725] GO:0001669; GO:0005737; GO:0015280; GO:0016324; GO:0031514; GO:0034706; GO:0035725 15915 XR_006396847.1 695 808 501 884 127 NA NA NA NA NA NA 15916 XM_029328854.2 16 0 0 0 0 Q68CZ6 1.75e-61 HAUS augmin-like complex subunit 3 Homo sapiens (Human) cell division [GO:0051301]; centrosome cycle [GO:0007098]; spindle assembly [GO:0051225] GO:0005813; GO:0005829; GO:0007098; GO:0051225; GO:0051301; GO:0070652; GO:0072686; GO:1990498 15917 XM_044307927.1 1700 21 943 1560 2202 A0A0R4IBK5 1.6e-122 E3 ubiquitin-protein ligase rnf213-alpha (EC 2.3.2.27) (EC 3.6.4.-) (E3 ubiquitin-lipopolysaccharide ligase rnf213-alpha) (EC 2.3.2.-) (Mysterin-A) (Mysterin-alpha) (RING finger protein 213-A) (RING finger protein 213-alpha) Danio rerio (Zebrafish) (Brachydanio rerio) blood circulation [GO:0008015]; defense response to bacterium [GO:0042742]; immune system process [GO:0002376]; lipid droplet formation [GO:0140042]; lipid ubiquitination [GO:0120323]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein K63-linked ubiquitination [GO:0070534]; regulation of lipid metabolic process [GO:0019216]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]; xenophagy [GO:0098792] GO:0002040; GO:0002376; GO:0004842; GO:0005524; GO:0005730; GO:0005811; GO:0005829; GO:0006511; GO:0008015; GO:0016887; GO:0019216; GO:0042742; GO:0046872; GO:0061630; GO:0070534; GO:0098792; GO:0120323; GO:0140042; GO:2000051 15918 XM_044316004.1 28 0 0 34 0 NA NA NA NA NA NA 15919 XM_044314170.1 187 64 202 73 133 Q96RW7 1.23e-25 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 15920 XM_044314170.1 187 64 202 73 133 Q96RW7 1.72e-24 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 15921 XR_006391313.1 1382 795 595 1334 909 NA NA NA NA NA NA 15922 XM_044309732.1 0 0 8 6 5 O88572 2.37e-158 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 15923 XM_044309732.1 0 0 8 6 5 O88572 7.98e-139 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 15924 XM_044309732.1 0 0 8 6 5 O88572 2.5e-130 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 15925 XM_044323053.1 693 336 171 443 698 NA NA NA NA NA NA 15926 XM_044327537.1 0 0 0 0 22 P27467 1.36e-108 Protein Wnt-3a Mus musculus (Mouse) animal organ morphogenesis [GO:0009887]; anterior/posterior pattern specification [GO:0009952]; axis elongation involved in somitogenesis [GO:0090245]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; B cell proliferation [GO:0042100]; BMP signaling pathway [GO:0030509]; calcium ion transmembrane transport via low voltage-gated calcium channel [GO:0090676]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment [GO:0061317]; cardiac muscle cell fate commitment [GO:0060923]; cell fate commitment [GO:0045165]; cell population proliferation [GO:0008283]; cell proliferation in forebrain [GO:0021846]; cell proliferation in midbrain [GO:0033278]; cell-cell signaling [GO:0007267]; COP9 signalosome assembly [GO:0010387]; determination of left/right symmetry [GO:0007368]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral neural tube patterning [GO:0021904]; extracellular matrix organization [GO:0030198]; fat cell differentiation [GO:0045444]; heart looping [GO:0001947]; hemopoiesis [GO:0030097]; hippocampus development [GO:0021766]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; mammary gland development [GO:0030879]; mesoderm development [GO:0007498]; midbrain development [GO:0030901]; modulation of chemical synaptic transmission [GO:0050804]; myoblast differentiation [GO:0045445]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of dopaminergic neuron differentiation [GO:1904339]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of heart induction by canonical Wnt signaling pathway [GO:0003136]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron death [GO:1901215]; negative regulation of neuron projection development [GO:0010977]; neurogenesis [GO:0022008]; neuron differentiation [GO:0030182]; osteoblast differentiation [GO:0001649]; paraxial mesodermal cell fate commitment [GO:0048343]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation [GO:2000081]; positive regulation of cardiac muscle cell differentiation [GO:2000727]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell-cell adhesion mediated by cadherin [GO:2000049]; positive regulation of collateral sprouting in absence of injury [GO:0048697]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of dermatome development [GO:0061184]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of hepatocyte proliferation [GO:2000347]; positive regulation of mesodermal cell fate specification [GO:0048337]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein binding [GO:0032092]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor internalization [GO:0002092]; positive regulation of skeletal muscle tissue development [GO:0048643]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; protein localization [GO:0008104]; regulation of axonogenesis [GO:0050770]; regulation of cell differentiation [GO:0045595]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of postsynapse to nucleus signaling pathway [GO:1905539]; regulation of presynapse assembly [GO:1905606]; regulation of RNA biosynthetic process [GO:2001141]; regulation of synapse organization [GO:0050807]; secondary palate development [GO:0062009]; signal transduction [GO:0007165]; skeletal muscle cell differentiation [GO:0035914]; somatic stem cell division [GO:0048103]; somitogenesis [GO:0001756]; spinal cord association neuron differentiation [GO:0021527]; transcription by RNA polymerase II [GO:0006366]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874] GO:0001649; GO:0001701; GO:0001756; GO:0001819; GO:0001934; GO:0001947; GO:0002092; GO:0003136; GO:0003713; GO:0005102; GO:0005109; GO:0005125; GO:0005576; GO:0005615; GO:0005788; GO:0006366; GO:0007165; GO:0007267; GO:0007368; GO:0007409; GO:0007411; GO:0007498; GO:0008104; GO:0008283; GO:0008284; GO:0009887; GO:0009952; GO:0009986; GO:0010387; GO:0010628; GO:0010977; GO:0016055; GO:0019904; GO:0021527; GO:0021766; GO:0021846; GO:0021874; GO:0021904; GO:0022008; GO:0030097; GO:0030168; GO:0030182; GO:0030198; GO:0030509; GO:0030879; GO:0030890; GO:0030901; GO:0032092; GO:0033138; GO:0033278; GO:0035914; GO:0036342; GO:0039706; GO:0042100; GO:0042472; GO:0042802; GO:0043280; GO:0045165; GO:0045202; GO:0045444; GO:0045445; GO:0045595; GO:0045599; GO:0045860; GO:0045893; GO:0045944; GO:0048018; GO:0048103; GO:0048337; GO:0048343; GO:0048643; GO:0048697; GO:0048843; GO:0050768; GO:0050770; GO:0050804; GO:0050807; GO:0051091; GO:0060070; GO:0060923; GO:0061098; GO:0061184; GO:0061317; GO:0062009; GO:0070507; GO:0070527; GO:0071542; GO:0090245; GO:0090263; GO:0090676; GO:0098978; GO:1901215; GO:1903078; GO:1904339; GO:1905539; GO:1905606; GO:1990851; GO:1990909; GO:2000049; GO:2000081; GO:2000179; GO:2000347; GO:2000727; GO:2001141 15927 XR_006397938.1 681 863 425 603 749 Q8NBN7 1.81e-42 Retinol dehydrogenase 13 (EC 1.1.1.300) (Short chain dehydrogenase/reductase family 7C member 3) Homo sapiens (Human) eye photoreceptor cell development [GO:0042462]; response to high light intensity [GO:0009644]; retina layer formation [GO:0010842]; retinal metabolic process [GO:0042574] GO:0005743; GO:0009644; GO:0010842; GO:0042462; GO:0042574; GO:0052650 15928 XM_044328712.1 0 0 3 8 5 NA NA NA NA NA NA 15929 XM_029356688.2 191 137 75 89 135 Q9SR22 8.23e-65 Pectin acetylesterase 5 (EC 3.1.1.-) Arabidopsis thaliana (Mouse-ear cress) cell wall organization [GO:0071555] GO:0005576; GO:0009505; GO:0052793; GO:0071555 15930 XR_006391421.1 4 0 5 0 8 NA NA NA NA NA NA 15931 XM_044313686.1 5 0 0 1 11 Q09575 3.79e-41 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 15932 XM_044316490.1 27 0 1 28 49 NA NA NA NA NA NA 15933 XM_029343994.2 603 540 544 614 700 Q91584 3.03e-71 ELAV-like protein 3 (Protein ElrC) Xenopus laevis (African clawed frog) cell differentiation [GO:0030154]; nervous system development [GO:0007399] GO:0003723; GO:0007399; GO:0030154; GO:1990904 15934 XM_044326852.1 0 18 2 7 32 NA NA NA NA NA NA 15935 XM_044328214.1 193 204 90 164 144 NA NA NA NA NA NA 15936 XR_006395659.1 3201 1772 1594 1194 2280 NA NA NA NA NA NA 15937 XM_029330666.2 390 453 564 649 813 NA NA NA NA NA NA 15938 XM_029333451.2 2463 1667 1492 2354 2610 Q8IWV8 0 E3 ubiquitin-protein ligase UBR2 (EC 2.3.2.27) (N-recognin-2) (RING-type E3 ubiquitin transferase UBR2) (Ubiquitin-protein ligase E3-alpha-2) (Ubiquitin-protein ligase E3-alpha-II) Homo sapiens (Human) cellular response to leucine [GO:0071233]; heterochromatin formation [GO:0031507]; histone H2A ubiquitination [GO:0033522]; male meiosis I [GO:0007141]; male meiotic nuclear division [GO:0007140]; negative regulation of TOR signaling [GO:0032007]; negative regulation of transposition [GO:0010529]; protein ubiquitination [GO:0016567]; reciprocal meiotic recombination [GO:0007131]; spermatogenesis [GO:0007283]; ubiquitin-dependent protein catabolic process via the N-end rule pathway [GO:0071596] GO:0000151; GO:0000785; GO:0005634; GO:0005737; GO:0005829; GO:0007131; GO:0007140; GO:0007141; GO:0007283; GO:0008270; GO:0010529; GO:0016567; GO:0031507; GO:0032007; GO:0033522; GO:0061630; GO:0070728; GO:0071233; GO:0071596 15939 XM_029336330.2 9 0 0 0 0 Q5BK48 7.6e-102 Tetratricopeptide repeat protein 5 (TPR repeat protein 5) (Stress-responsive activator of p300) (Protein Strap) Rattus norvegicus (Rat) cellular response to DNA damage stimulus [GO:0006974]; cellular response to starvation [GO:0009267]; DNA repair [GO:0006281]; positive regulation of mRNA catabolic process [GO:0061014]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0003677; GO:0003682; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005759; GO:0005829; GO:0006281; GO:0006974; GO:0009267; GO:0031410; GO:0043022; GO:0045944; GO:0061014 15940 XM_044326899.1 3647 1068 1275 1962 772 NA NA NA NA NA NA 15941 XM_029339019.2 77 16 61 155 52 NA NA NA NA NA NA 15942 XM_044320494.1 0 0 0 0 46 NA NA NA NA NA NA 15943 XR_006396789.1 26 33 3 8 4 NA NA NA NA NA NA 15944 XM_029355063.2 786 504 340 1159 646 Q96CN9 4.37e-81 GRIP and coiled-coil domain-containing protein 1 (Golgi coiled-coil protein 1) Homo sapiens (Human) NA GO:0000138; GO:0000139; GO:0005794; GO:0005829; GO:0031267 15945 XM_044309966.1 6 4 0 24 7 NA NA NA NA NA NA 15946 XM_044322891.1 1530 496 386 497 561 NA NA NA NA NA NA 15947 XM_044322394.1 0 0 88 76 238 Q96AY4 6.14e-94 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15948 XM_044322394.1 0 0 88 76 238 Q96AY4 2.51e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15949 XM_044322394.1 0 0 88 76 238 Q96AY4 2.81e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15950 XM_044322394.1 0 0 88 76 238 Q96AY4 2.24e-83 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15951 XM_044322394.1 0 0 88 76 238 Q96AY4 4.26e-83 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15952 XM_044322394.1 0 0 88 76 238 Q96AY4 9.83e-82 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15953 XM_044322394.1 0 0 88 76 238 Q96AY4 2.05e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15954 XR_006393675.1 1379 74 2080 116 4384 NA NA NA NA NA NA 15955 XM_029339570.2 22 2 2 0 50 Q09575 3.22e-69 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 15956 XM_029344833.2 989 2105 866 591 885 NA NA NA NA NA NA 15957 XR_006393914.1 41 2 25 5 151 NA NA NA NA NA NA 15958 XM_029330051.2 76 215 104 262 110 NA NA NA NA NA NA 15959 XM_029341178.2 55 93 75 191 108 NA NA NA NA NA NA 15960 XM_029345802.2 4 221 6 157 333 NA NA NA NA NA NA 15961 XM_044321958.1 205 99 74 151 80 Q8BHB0 4.67e-26 Nucleotide-binding oligomerization domain-containing protein 1 (Caspase recruitment domain-containing protein 4) Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cellular response to muramyl dipeptide [GO:0071225]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; ERK1 and ERK2 cascade [GO:0070371]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of cell death [GO:0010942]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of xenophagy [GO:1904417]; regulation of apoptotic process [GO:0042981]; stress-activated MAPK cascade [GO:0051403]; xenophagy [GO:0098792] GO:0002221; GO:0002606; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006915; GO:0006919; GO:0007249; GO:0007254; GO:0010942; GO:0016045; GO:0016323; GO:0016324; GO:0032731; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0035556; GO:0038187; GO:0042742; GO:0042802; GO:0042803; GO:0042981; GO:0043123; GO:0043280; GO:0044877; GO:0045087; GO:0045335; GO:0046330; GO:0050700; GO:0050830; GO:0051000; GO:0051092; GO:0051403; GO:0060907; GO:0070371; GO:0070374; GO:0071225; GO:0098792; GO:1901224; GO:1904417 15962 XM_029350816.2 81 72 11 0 35 Q6GMK0 4.46e-153 Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B (EC 2.4.1.145) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVb) (GlcNAc-T IVb) (GnT-IVb) (N-acetylglucosaminyltransferase IVb) (UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVb) Danio rerio (Zebrafish) (Brachydanio rerio) protein glycosylation [GO:0006486]; protein N-linked glycosylation [GO:0006487] GO:0000139; GO:0005783; GO:0005793; GO:0005795; GO:0006486; GO:0006487; GO:0008375; GO:0008454; GO:0046872 15963 XM_029344839.2 134 0 198 203 0 Q9H3L0 2.86e-69 Cobalamin trafficking protein CblD (CblD) (Methylmalonic aciduria and homocystinuria type D protein, mitochondrial) Homo sapiens (Human) cobalamin metabolic process [GO:0009235] GO:0005737; GO:0005739; GO:0005829; GO:0009235 15964 XR_006395501.1 73 9 9 35 34 NA NA NA NA NA NA 15965 XM_044326273.1 122 116 1457 120 117 Q96MB7 1.86e-33 Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease) Homo sapiens (Human) NA GO:0004518; GO:0005634; GO:0005829; GO:0005886; GO:0034451; GO:0046872 15966 XM_044324139.1 0 0 0 28 0 NA NA NA NA NA NA 15967 XM_044314486.1 0 0 0 75 25 NA NA NA NA NA NA 15968 XM_044324095.1 0 7 0 10 8 NA NA NA NA NA NA 15969 XM_029336016.2 332 380 371 571 190 Q7Z2H8 4.85e-24 Proton-coupled amino acid transporter 1 (Proton/amino acid transporter 1) (hPAT1) (Solute carrier family 36 member 1) Homo sapiens (Human) alanine transport [GO:0032328]; amino acid import across plasma membrane [GO:0089718]; amino acid transmembrane transport [GO:0003333]; amino acid transport [GO:0006865]; glycine transport [GO:0015816]; ion transport [GO:0006811]; L-alanine transport [GO:0015808]; proline transmembrane transport [GO:0035524]; proline transport [GO:0015824]; proton transmembrane transport [GO:1902600]; taurine transport [GO:0015734] GO:0003333; GO:0005280; GO:0005297; GO:0005368; GO:0005765; GO:0005783; GO:0005886; GO:0006811; GO:0006865; GO:0015171; GO:0015179; GO:0015180; GO:0015187; GO:0015193; GO:0015734; GO:0015808; GO:0015816; GO:0015824; GO:0016324; GO:0022858; GO:0032328; GO:0035524; GO:0089718; GO:1902600 15970 XM_029334911.2 291 132 496 490 971 NA NA NA NA NA NA 15971 XM_029353601.2 47 1 0 0 2 NA NA NA NA NA NA 15972 XM_029353966.2 767 568 391 626 594 NA NA NA NA NA NA 15973 XM_044325994.1 27 35 15 46 4 P49219 8.88e-25 Melatonin receptor type 1C (Mel-1C-R) (Mel1c (alpha) receptor) (Mel1c receptor) Xenopus laevis (African clawed frog) NA GO:0005886; GO:0008502 15974 XM_029332299.2 99 0 0 73 40 Q66JZ4 5.23e-65 T-cell activation inhibitor, mitochondrial (Tolerance associated gene-1 protein) (TOAG-1) Mus musculus (Mouse) NA GO:0005739 15975 XR_006397771.1 0 0 0 0 32 NA NA NA NA NA NA 15976 XM_029349326.2 29 0 0 6 9 Q9Y222 3.59e-130 Cyclin-D-binding Myb-like transcription factor 1 (hDMTF1) (Cyclin-D-interacting Myb-like protein 1) (hDMP1) Homo sapiens (Human) cell cycle [GO:0007049]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000976; GO:0000978; GO:0000981; GO:0001228; GO:0003700; GO:0005634; GO:0005654; GO:0005829; GO:0006355; GO:0006357; GO:0007049 15977 XR_003827425.2 67 66 75 51 6 NA NA NA NA NA NA 15978 XM_044322650.1 0 0 0 4 6 Q09575 3.89e-33 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 15979 XR_006395524.1 40 0 0 41 0 NA NA NA NA NA NA 15980 XR_006392003.1 30 1 0 0 28 NA NA NA NA NA NA 15981 XM_044321530.1 43 114 36 52 290 NA NA NA NA NA NA 15982 XM_029349086.2 2842 1521 905 2148 1077 F8W2M8 0 Tripeptidyl-peptidase 1 (TPP-1) (EC 3.4.14.9) (Tripeptidyl aminopeptidase) (Tripeptidyl-peptidase I) (TPP-I) Danio rerio (Zebrafish) (Brachydanio rerio) central nervous system development [GO:0007417]; locomotory behavior [GO:0007626]; neurogenesis [GO:0022008]; proteolysis [GO:0006508] GO:0004175; GO:0004252; GO:0005764; GO:0006508; GO:0007417; GO:0007626; GO:0008240; GO:0022008; GO:0046872 15983 XM_029331217.2 2433 1786 859 1909 1282 NA NA NA NA NA NA 15984 XM_029352409.2 48 17 74 98 127 Q0D2E8 4.98e-168 Protein RFT1 homolog Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) carbohydrate transport [GO:0008643]; dolichol-linked oligosaccharide biosynthetic process [GO:0006488] GO:0006488; GO:0008643; GO:0016020 15985 XM_044307307.1 1311 199 835 170 1313 E9PSU6 0 Pecanex-like protein 1 (Pecanex 1) (Pecanex homolog protein 1) Rattus norvegicus (Rat) NA GO:0016020 15986 XM_044307307.1 1311 199 835 170 1313 E9PSU6 1.1e-28 Pecanex-like protein 1 (Pecanex 1) (Pecanex homolog protein 1) Rattus norvegicus (Rat) NA GO:0016020 15987 XM_044307307.1 1311 199 835 170 1313 E9PSU6 4.07e-21 Pecanex-like protein 1 (Pecanex 1) (Pecanex homolog protein 1) Rattus norvegicus (Rat) NA GO:0016020 15988 XM_044310053.1 26 1 5 10 39 NA NA NA NA NA NA 15989 XM_029357192.2 1495 1445 1102 1769 2134 Q9H867 3.48e-55 Protein N-lysine methyltransferase METTL21D (EC 2.1.1.-) (Methyltransferase-like protein 21D) (VCP lysine methyltransferase) (VCP-KMT) (Valosin-containing protein lysine methyltransferase) Homo sapiens (Human) negative regulation of ATP-dependent activity [GO:0032780]; peptidyl-lysine methylation [GO:0018022]; peptidyl-lysine trimethylation [GO:0018023]; protein methylation [GO:0006479] GO:0005737; GO:0005829; GO:0006479; GO:0016279; GO:0018022; GO:0018023; GO:0018024; GO:0032780; GO:0032991; GO:0051117 15990 XM_029336013.2 1398 936 789 1196 1123 Q6Q0C0 0 E3 ubiquitin-protein ligase TRAF7 (EC 2.3.2.27) (RING finger and WD repeat-containing protein 1) (RING finger protein 119) (RING-type E3 ubiquitin transferase TRAF7) (TNF receptor-associated factor 7) Homo sapiens (Human) apoptotic process [GO:0006915]; Notch signaling pathway [GO:0007219]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of MAPK cascade [GO:0043410]; protein ubiquitination [GO:0016567]; regulation of ERK1 and ERK2 cascade [GO:0070372]; ribosomal large subunit assembly [GO:0000027] GO:0000027; GO:0000151; GO:0004842; GO:0005730; GO:0005886; GO:0006915; GO:0007219; GO:0008270; GO:0016567; GO:0031410; GO:0043231; GO:0043410; GO:0070372; GO:2001235 15991 XM_044312240.1 0 0 0 2 12 NA NA NA NA NA NA 15992 XM_029339297.2 464 583 248 300 537 NA NA NA NA NA NA 15993 XM_029340855.2 370 186 274 388 491 Q9CYC3 5.3e-80 Transmembrane protein 39A Mus musculus (Mouse) autophagy [GO:0006914]; negative regulation of autophagosome assembly [GO:1902902]; negative regulation of autophagosome maturation [GO:1901097]; positive regulation of viral genome replication [GO:0045070] GO:0005789; GO:0006914; GO:0016020; GO:0045070; GO:1901097; GO:1902902 15994 XM_044323668.1 15 0 4 0 4 NA NA NA NA NA NA 15995 XM_029333356.2 526 557 140 1172 1168 NA NA NA NA NA NA 15996 XM_029355544.2 1130 810 666 828 680 NA NA NA NA NA NA 15997 XM_029335119.2 12 7 28 27 16 Q20191 4.09e-44 Zinc metalloproteinase nas-13 (EC 3.4.24.-) (Nematode astacin 13) Caenorhabditis elegans proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0006508; GO:0008270 15998 XM_029349068.2 0 41 0 0 0 NA NA NA NA NA NA 15999 XM_029338401.2 1115 263 827 683 621 Q96NN9 2.59e-162 Apoptosis-inducing factor 3 (EC 1.-.-.-) (Apoptosis-inducing factor-like protein) Homo sapiens (Human) execution phase of apoptosis [GO:0097194] GO:0005737; GO:0005739; GO:0005743; GO:0005783; GO:0005829; GO:0016651; GO:0046872; GO:0050660; GO:0051537; GO:0097194 16000 XM_029358391.2 1029 1899 1330 1766 1919 Q9VYY9 5.33e-127 Ecotropic viral integration site 5 ortholog Drosophila melanogaster (Fruit fly) activation of GTPase activity [GO:0090630]; regulation of cell migration [GO:0030334]; regulation of GTPase activity [GO:0043087]; regulation of protein localization [GO:0032880] GO:0005096; GO:0005737; GO:0005768; GO:0005794; GO:0030334; GO:0031267; GO:0031982; GO:0032880; GO:0043087; GO:0090630 16001 XM_044315729.1 0 0 2 0 11 NA NA NA NA NA NA 16002 XM_029345867.2 270 683 172 317 62 NA NA NA NA NA NA 16003 XM_029345300.2 75 103 91 46 249 NA NA NA NA NA NA 16004 XM_029356702.2 272 141 95 183 169 Q9WUV0 9.95e-150 Origin recognition complex subunit 5 Mus musculus (Mouse) DNA replication [GO:0006260]; DNA replication initiation [GO:0006270]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0000808; GO:0003688; GO:0005524; GO:0005654; GO:0005664; GO:0005829; GO:0006260; GO:0006270; GO:0006275 16005 XM_029353963.2 1413 2263 969 1369 906 Q8TCF1 4.14e-53 AN1-type zinc finger protein 1 (Zinc finger AN1-type-containing protein 1) Homo sapiens (Human) cellular response to arsenite ion [GO:1903843]; positive regulation of intracellular protein transport [GO:0090316]; stress granule disassembly [GO:0035617] GO:0005737; GO:0008270; GO:0010494; GO:0035617; GO:0070628; GO:0090316; GO:1903843 16006 XM_029358102.2 0 5 21 0 0 Q9EQD2 1.36e-26 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 16007 XM_044312479.1 526 315 446 618 619 Q9NZM1 0 Myoferlin (Fer-1-like protein 3) Homo sapiens (Human) blood circulation [GO:0008015]; membrane fusion [GO:0061025]; muscle contraction [GO:0006936]; plasma membrane organization [GO:0007009]; plasma membrane repair [GO:0001778]; T-tubule organization [GO:0033292] GO:0001778; GO:0005543; GO:0005635; GO:0005886; GO:0005901; GO:0006936; GO:0007009; GO:0008015; GO:0030659; GO:0031410; GO:0031965; GO:0033292; GO:0043231; GO:0046872; GO:0061025; GO:0070062 16008 XR_003824630.2 93 160 50 72 51 NA NA NA NA NA NA 16009 XM_029346164.2 175 83 123 119 149 Q6GPU3 1.58e-125 Denticleless protein homolog B Xenopus laevis (African clawed frog) cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; regulation of cell cycle [GO:0051726]; response to UV [GO:0009411]; rhythmic process [GO:0048511]; translesion synthesis [GO:0019985]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000209; GO:0005634; GO:0005694; GO:0005737; GO:0005813; GO:0006260; GO:0006511; GO:0006513; GO:0006974; GO:0007095; GO:0009411; GO:0019985; GO:0031464; GO:0031465; GO:0048511; GO:0051726 16010 XM_044329222.1 124 95 62 80 82 NA NA NA NA NA NA 16011 XM_029328965.2 233 242 115 100 400 Q9D2E2 3.45e-97 Target of EGR1 protein 1 Mus musculus (Mouse) RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; snRNA 3'-end processing [GO:0034472] GO:0000175; GO:0003723; GO:0004535; GO:0005654; GO:0005730; GO:0005737; GO:0015030; GO:0016604; GO:0016607; GO:0017069; GO:0034472; GO:0046872; GO:0090503 16012 XR_006394654.1 0 3 24 21 7 NA NA NA NA NA NA 16013 XM_044329109.1 0 50 15 18 17 Q61184 7.72e-37 Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor) Mus musculus (Mouse) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; circadian rhythm [GO:0007623]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of insulin secretion [GO:0046676] GO:0004930; GO:0005886; GO:0007186; GO:0007193; GO:0007623; GO:0008502; GO:0042562; GO:0043025; GO:0043235; GO:0046676; GO:0097159 16014 XR_006391306.1 37 0 0 0 5 NA NA NA NA NA NA 16015 XM_044326839.1 17 30 15 49 19 NA NA NA NA NA NA 16016 XM_029347650.2 110 98 114 5 87 NA NA NA NA NA NA 16017 XM_044323926.1 480 521 645 271 561 O95263 0 High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B (HsPDE8B) (EC 3.1.4.53) (Cell proliferation-inducing gene 22 protein) Homo sapiens (Human) behavioral fear response [GO:0001662]; cAMP catabolic process [GO:0006198]; negative regulation of steroid hormone biosynthetic process [GO:0090032]; neuromuscular process controlling balance [GO:0050885]; operant conditioning [GO:0035106]; signal transduction [GO:0007165]; visual learning [GO:0008542] GO:0001662; GO:0004114; GO:0004115; GO:0005829; GO:0006198; GO:0007165; GO:0008542; GO:0035106; GO:0046872; GO:0050885; GO:0090032 16018 XM_029347255.2 0 0 0 0 15 NA NA NA NA NA NA 16019 XM_029334645.2 3647 2302 1593 2956 3027 Q7ZVY5 0 Citrate synthase, mitochondrial (EC 2.3.3.1) (Citrate (Si)-synthase) Danio rerio (Zebrafish) (Brachydanio rerio) carbohydrate metabolic process [GO:0005975]; citrate metabolic process [GO:0006101]; response to activity [GO:0014823]; tricarboxylic acid cycle [GO:0006099] GO:0004108; GO:0005759; GO:0005975; GO:0006099; GO:0006101; GO:0014823 16020 XR_003828622.2 2 5 10 2 14 NA NA NA NA NA NA 16021 XR_006397160.1 242 208 84 175 265 NA NA NA NA NA NA 16022 XM_029324749.2 339 192 407 163 286 Q54RA4 6.42e-55 Probable iron/ascorbate oxidoreductase DDB_G0283291 (EC 1.14.-.-) Dictyostelium discoideum (Social amoeba) NA GO:0046872; GO:0051213 16023 XM_029341969.2 272 208 136 185 212 Q4KMD3 1.22e-51 U11/U12 small nuclear ribonucleoprotein 35 kDa protein (U11/U12 snRNP 35 kDa protein) (U1 snRNP-binding protein homolog) Danio rerio (Zebrafish) (Brachydanio rerio) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0003729; GO:0005689; GO:0017069 16024 XR_006397573.1 195 34 157 84 81 NA NA NA NA NA NA 16025 XM_044328559.1 253 120 49 204 132 NA NA NA NA NA NA 16026 XM_044312076.1 23 0 8 0 0 NA NA NA NA NA NA 16027 XM_029346470.2 324 519 356 479 414 Q14549 1.92e-34 Homeobox protein GBX-1 (Gastrulation and brain-specific homeobox protein 1) Homo sapiens (Human) adult walking behavior [GO:0007628]; neuron fate commitment [GO:0048663]; proprioception [GO:0019230]; regulation of nervous system development [GO:0051960]; regulation of transcription by RNA polymerase II [GO:0006357]; sensory neuron axon guidance [GO:0097374]; spinal cord motor neuron differentiation [GO:0021522] GO:0000785; GO:0000977; GO:0000981; GO:0005634; GO:0006357; GO:0007628; GO:0019230; GO:0021522; GO:0048663; GO:0051960; GO:0097374 16028 XM_044311489.1 6 0 10 0 4 NA NA NA NA NA NA 16029 XM_029342907.2 68 27 24 0 53 Q8BTQ0 7.64e-88 Polycomb group RING finger protein 3 (RING finger protein 3A) Mus musculus (Mouse) histone H2A-K119 monoubiquitination [GO:0036353]; inactivation of X chromosome by genomic imprinting [GO:0060819]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0005634; GO:0005654; GO:0006357; GO:0031519; GO:0035102; GO:0036353; GO:0046872; GO:0060819 16030 XM_029349298.2 60 53 23 78 41 P04274 7.95e-24 Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor) Mesocricetus auratus (Golden hamster) activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; bone resorption [GO:0045453]; brown fat cell differentiation [GO:0050873]; cellular response to amyloid-beta [GO:1904646]; desensitization of G protein-coupled receptor signaling pathway by arrestin [GO:0002032]; diet induced thermogenesis [GO:0002024]; heat generation [GO:0031649]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of smooth muscle contraction [GO:0045986]; norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0002025]; positive regulation of AMPA receptor activity [GO:2000969]; positive regulation of autophagosome maturation [GO:1901098]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of lipophagy [GO:1904504]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mini excitatory postsynaptic potential [GO:0061885]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor-mediated endocytosis [GO:0006898]; regulation of sodium ion transport [GO:0002028]; response to cold [GO:0009409]; smooth muscle contraction [GO:0006939]; transcription by RNA polymerase II [GO:0006366] GO:0001540; GO:0002024; GO:0002025; GO:0002028; GO:0002032; GO:0004941; GO:0005634; GO:0005769; GO:0005794; GO:0006366; GO:0006898; GO:0006939; GO:0007189; GO:0007190; GO:0008179; GO:0009409; GO:0010739; GO:0015459; GO:0016324; GO:0030501; GO:0031649; GO:0040015; GO:0042803; GO:0043235; GO:0043410; GO:0044877; GO:0045453; GO:0045944; GO:0045986; GO:0050873; GO:0051380; GO:0061885; GO:0071902; GO:0098992; GO:0120162; GO:1901098; GO:1904504; GO:1904646; GO:2000969 16031 XR_006391388.1 41 17 0 0 14 NA NA NA NA NA NA 16032 XM_029351743.2 415 385 701 200 220 NA NA NA NA NA NA 16033 XM_044312919.1 165 273 56 57 135 P15374 9.05e-92 Ubiquitin carboxyl-terminal hydrolase isozyme L3 (UCH-L3) (EC 3.4.19.12) (Ubiquitin thioesterase L3) Homo sapiens (Human) post-translational protein modification [GO:0043687]; protein catabolic process [GO:0030163]; protein deubiquitination [GO:0016579]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004843; GO:0005654; GO:0005737; GO:0005829; GO:0006511; GO:0008233; GO:0016567; GO:0016579; GO:0019784; GO:0030163; GO:0043130; GO:0043687 16034 XM_029325900.2 2262 2917 1240 2907 1742 NA NA NA NA NA NA 16035 XM_029358493.2 4282 28 8 21 26 Q6AYC8 1.25e-36 SH2 domain-containing protein 4A Rattus norvegicus (Rat) NA GO:0005737; GO:0005829; GO:0019902 16036 XR_006392264.1 316 0 0 0 0 NA NA NA NA NA NA 16037 XM_029357158.2 38 16 38 24 79 A6NJT0 5.5e-26 Homeobox protein unc-4 homolog (Homeobox protein Uncx4.1) Homo sapiens (Human) cartilage condensation [GO:0001502]; common myeloid progenitor cell proliferation [GO:0035726]; dorsal spinal cord development [GO:0021516]; olfactory bulb interneuron differentiation [GO:0021889]; pattern specification process [GO:0007389]; regulation of cell differentiation [GO:0045595]; regulation of gene expression [GO:0010468] GO:0000785; GO:0000981; GO:0001502; GO:0005634; GO:0007389; GO:0010468; GO:0021516; GO:0021889; GO:0035726; GO:0045595; GO:1990837 16038 XM_029333413.2 103 149 182 162 160 Q6PEM8 4.47e-44 Proton-coupled folate transporter (Heme carrier protein 1) (PCFT/HCP1) (Solute carrier family 46 member 1) Mus musculus (Mouse) folate import across plasma membrane [GO:1904447]; folate transmembrane transport [GO:0098838]; folic acid transport [GO:0015884]; heme transport [GO:0015886]; proton transmembrane transport [GO:1902600]; transmembrane transport [GO:0055085] GO:0005542; GO:0005737; GO:0005768; GO:0005886; GO:0008517; GO:0010008; GO:0015078; GO:0015232; GO:0015293; GO:0015350; GO:0015884; GO:0015886; GO:0016020; GO:0016323; GO:0016324; GO:0022857; GO:0031526; GO:0055085; GO:0098838; GO:0140211; GO:1902600; GO:1904447 16039 XM_029327946.2 183 137 0 225 420 Q96T23 2.42e-36 Remodeling and spacing factor 1 (Rsf-1) (HBV pX-associated protein 8) (Hepatitis B virus X-associated protein) (p325 subunit of RSF chromatin-remodeling complex) Homo sapiens (Human) chromatin remodeling [GO:0006338]; DNA-templated transcription initiation [GO:0006352]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-templated transcription [GO:0045892]; nucleosome assembly [GO:0006334]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of viral transcription [GO:0050434]; regulation of DNA-templated transcription [GO:0006355] GO:0003712; GO:0005634; GO:0005654; GO:0006334; GO:0006338; GO:0006352; GO:0006355; GO:0031213; GO:0042393; GO:0043392; GO:0045892; GO:0045893; GO:0045944; GO:0046872; GO:0050434; GO:0140751 16040 XM_029327946.2 183 137 0 225 420 Q96T23 2.68e-27 Remodeling and spacing factor 1 (Rsf-1) (HBV pX-associated protein 8) (Hepatitis B virus X-associated protein) (p325 subunit of RSF chromatin-remodeling complex) Homo sapiens (Human) chromatin remodeling [GO:0006338]; DNA-templated transcription initiation [GO:0006352]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-templated transcription [GO:0045892]; nucleosome assembly [GO:0006334]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of viral transcription [GO:0050434]; regulation of DNA-templated transcription [GO:0006355] GO:0003712; GO:0005634; GO:0005654; GO:0006334; GO:0006338; GO:0006352; GO:0006355; GO:0031213; GO:0042393; GO:0043392; GO:0045892; GO:0045893; GO:0045944; GO:0046872; GO:0050434; GO:0140751 16041 XR_006394878.1 72 48 110 117 70 NA NA NA NA NA NA 16042 XM_044323140.1 96 296 113 114 18 Q99570 9.22e-29 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 16043 XM_029334439.2 51 33 56 93 78 NA NA NA NA NA NA 16044 XM_044316204.1 39 0 251 394 0 NA NA NA NA NA NA 16045 XM_029342029.2 701 107 192 224 276 Q9EQS9 2.44e-90 Immunoglobulin superfamily DCC subclass member 4 (Neighbor of punc e11) (Protein DDM36) Mus musculus (Mouse) cell-cell adhesion [GO:0098609] GO:0005886; GO:0098609 16046 XM_044323868.1 59 0 0 80 0 NA NA NA NA NA NA 16047 XM_029336339.2 1136 1434 513 936 774 NA NA NA NA NA NA 16048 XM_044320334.1 853 69 576 127 1683 C0H693 1.27e-22 Small cysteine-rich protein 1 1 (Mcap-SCRiP1a) (SCRiP1a) Montipora capitata (Rice coral) NA GO:0005576; GO:0042151; GO:0090729 16049 XM_044309820.1 119 21 171 99 502 NA NA NA NA NA NA 16050 XM_029345188.2 1090 1342 911 1110 1062 Q9UKJ5 1.05e-51 Cysteine-rich hydrophobic domain-containing protein 2 (BrX-like translocated in leukemia) Homo sapiens (Human) NA GO:0005794; GO:0005798; GO:0005886; GO:0043231 16051 XM_044326964.1 7 0 0 0 0 NA NA NA NA NA NA 16052 XM_029339307.2 32 32 93 1 87 Q94BV5 1.37e-49 Flavin-containing monooxygenase FMO GS-OX-like 4 (EC 1.8.-.-) (Flavin-monooxygenase glucosinolate S-oxygenase-like 4) Arabidopsis thaliana (Mouse-ear cress) NA GO:0000325; GO:0004499; GO:0050660; GO:0050661 16053 XR_003824483.2 0 7 0 16 0 NA NA NA NA NA NA 16054 XM_029324023.2 424 388 482 648 642 Q7ZXV8 3.24e-49 BUB3-interacting and GLEBS motif-containing protein ZNF207 (BuGZ) (xBuGZ) (Zinc finger protein 207) Xenopus laevis (African clawed frog) attachment of spindle microtubules to kinetochore [GO:0008608]; cell division [GO:0051301]; microtubule bundle formation [GO:0001578]; microtubule polymerization [GO:0046785]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly [GO:0090307]; mitotic spindle assembly checkpoint signaling [GO:0007094]; protein stabilization [GO:0050821]; regulation of chromosome segregation [GO:0051983] GO:0000070; GO:0000776; GO:0001578; GO:0005634; GO:0005737; GO:0005819; GO:0005874; GO:0007094; GO:0008017; GO:0008608; GO:0046785; GO:0046872; GO:0050821; GO:0051301; GO:0051983; GO:0090307; GO:1990047 16055 XM_044316932.1 0 0 0 0 13 NA NA NA NA NA NA 16056 XM_029328777.2 0 0 0 0 6 Q5XXP2 6.36e-29 Melanopsin (Opsin-4) Phodopus sungorus (Striped hairy-footed hamster) (Djungarian hamster) hyaloid vascular plexus regression [GO:1990384]; optokinetic behavior [GO:0007634]; phototransduction [GO:0007602]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511]; visual perception [GO:0007601] GO:0005502; GO:0005886; GO:0007601; GO:0007602; GO:0007634; GO:0008020; GO:0016020; GO:0030424; GO:0030425; GO:0042752; GO:0043204; GO:0048511; GO:1990384 16057 XM_044306778.1 66 27 39 11 209 P0DP43 1.15e-37 Cation channel sperm-associated auxiliary subunit epsilon (CatSper-epsilon) (CatSperepsilon) (C1orf101-like protein) Mus musculus (Mouse) flagellated sperm motility [GO:0030317]; sperm capacitation [GO:0048240] GO:0030317; GO:0036128; GO:0048240; GO:0097228 16058 XM_029334771.2 405 868 168 461 400 Q4R4S5 4.09e-100 Lysosomal acid lipase/cholesteryl ester hydrolase (Acid cholesteryl ester hydrolase) (LAL) (EC 3.1.1.13) (Cholesteryl esterase) (Lipase A) (Sterol esterase) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) lipid catabolic process [GO:0016042] GO:0004771; GO:0005764; GO:0016042 16059 XM_029330542.2 2708 1903 1492 2574 2368 NA NA NA NA NA NA 16060 XM_044306942.1 31 41 11 24 20 Q92752 6.81e-27 Tenascin-R (TN-R) (Janusin) (Restrictin) Homo sapiens (Human) associative learning [GO:0008306]; axon extension involved in regeneration [GO:0048677]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198]; locomotory exploration behavior [GO:0035641]; long-term synaptic potentiation [GO:0060291]; negative regulation of axon extension involved in regeneration [GO:0048692]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of neuron projection development [GO:0010977]; negative regulation of synaptic transmission [GO:0050805]; neuroblast migration [GO:0097402]; neuromuscular process controlling balance [GO:0050885]; neuron cell-cell adhesion [GO:0007158]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transmission of nerve impulse [GO:0051971]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of cell migration [GO:0030334]; synapse organization [GO:0050808]; synaptic transmission, glutamatergic [GO:0035249]; telencephalon cell migration [GO:0022029] GO:0005102; GO:0005576; GO:0005615; GO:0007155; GO:0007158; GO:0007411; GO:0008306; GO:0009986; GO:0010977; GO:0022029; GO:0022408; GO:0030155; GO:0030198; GO:0030334; GO:0035249; GO:0035641; GO:0045121; GO:0045595; GO:0048677; GO:0048692; GO:0050805; GO:0050808; GO:0050885; GO:0051968; GO:0051971; GO:0060291; GO:0062023; GO:0072534; GO:0090733; GO:0097402; GO:0098685; GO:0098978 16061 XM_029355729.2 2031 1262 753 1328 1360 NA NA NA NA NA NA 16062 XR_006392970.1 71 1 3 1 338 NA NA NA NA NA NA 16063 XM_044328169.1 9 33 24 32 13 Q8TD57 8.03e-69 Dynein axonemal heavy chain 3 (Axonemal beta dynein heavy chain 3) (HsADHC3) (Ciliary dynein heavy chain 3) (Dnahc3-b) Homo sapiens (Human) cilium-dependent cell motility [GO:0060285]; microtubule-based movement [GO:0007018] GO:0003777; GO:0005524; GO:0005858; GO:0005874; GO:0007018; GO:0008569; GO:0030286; GO:0045505; GO:0051959; GO:0060285; GO:0097729 16064 XM_029346088.2 0 0 0 0 29 Q3MIT2 9.67e-103 tRNA pseudouridine synthase Pus10 (Hup10) (EC 5.4.99.25) (Coiled-coil domain-containing protein 139) (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA pseudouridylate synthase) (tRNA-uridine isomerase) Homo sapiens (Human) primary miRNA processing [GO:0031053]; tRNA pseudouridine synthesis [GO:0031119] GO:0005634; GO:0005737; GO:0005739; GO:0009982; GO:0031053; GO:0031119; GO:0046872; GO:0070878; GO:0106029 16065 XM_044322178.1 395 312 127 242 206 Q8K4H1 2.89e-66 Kynurenine formamidase (KFA) (KFase) (EC 3.5.1.9) (Arylformamidase) (N-formylkynurenine formamidase) (FKF) Mus musculus (Mouse) 'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; tryptophan catabolic process to kynurenine [GO:0019441] GO:0004061; GO:0005634; GO:0005737; GO:0005829; GO:0019441; GO:0034354 16066 XM_029357205.2 2 15 10 11 11 NA NA NA NA NA NA 16067 XM_029342239.2 1727 1577 721 1268 866 O88898 1.93e-57 Tumor protein 63 (p63) (Transformation-related protein 63) (TP63) (Tumor protein p73-like) (p73L) Mus musculus (Mouse) anatomical structure formation involved in morphogenesis [GO:0048646]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular senescence [GO:0090398]; chromatin remodeling [GO:0006338]; cloacal septation [GO:0060197]; cranial skeletal system development [GO:1904888]; ectoderm and mesoderm interaction [GO:0007499]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; epidermal cell differentiation [GO:0009913]; epidermal cell division [GO:0010481]; epidermis development [GO:0008544]; epithelial cell development [GO:0002064]; epithelial cell differentiation [GO:0030855]; establishment of planar polarity [GO:0001736]; establishment of skin barrier [GO:0061436]; female genitalia morphogenesis [GO:0048807]; hair follicle development [GO:0001942]; hair follicle morphogenesis [GO:0031069]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; keratinocyte differentiation [GO:0030216]; keratinocyte proliferation [GO:0043616]; morphogenesis of a polarized epithelium [GO:0001738]; multicellular organism aging [GO:0010259]; negative regulation of cellular senescence [GO:2000773]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of keratinocyte differentiation [GO:0045617]; negative regulation of mesoderm development [GO:2000381]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron apoptotic process [GO:0051402]; Notch signaling pathway [GO:0007219]; odontogenesis of dentin-containing tooth [GO:0042475]; pattern specification process [GO:0007389]; polarized epithelial cell differentiation [GO:0030859]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cell cycle G1/S phase transition [GO:1902808]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of fibroblast apoptotic process [GO:2000271]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of somatic stem cell population maintenance [GO:1904674]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; prostate gland development [GO:0030850]; prostatic bud formation [GO:0060513]; protein tetramerization [GO:0051262]; proximal/distal pattern formation [GO:0009954]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of epidermal cell division [GO:0010482]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal system development [GO:0001501]; skin epidermis development [GO:0098773]; skin morphogenesis [GO:0043589]; spermatogenesis [GO:0007283]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; stem cell differentiation [GO:0048863]; stem cell proliferation [GO:0072089]; sympathetic nervous system development [GO:0048485]; transcription by RNA polymerase II [GO:0006366] GO:0000122; GO:0000785; GO:0000977; GO:0000978; GO:0000981; GO:0001228; GO:0001501; GO:0001736; GO:0001738; GO:0001942; GO:0002039; GO:0002064; GO:0003677; GO:0003682; GO:0003684; GO:0003690; GO:0003700; GO:0005634; GO:0005654; GO:0005737; GO:0005791; GO:0006338; GO:0006357; GO:0006366; GO:0006915; GO:0006974; GO:0007219; GO:0007283; GO:0007389; GO:0007499; GO:0008284; GO:0008544; GO:0009887; GO:0009913; GO:0009954; GO:0010259; GO:0010481; GO:0010482; GO:0010838; GO:0019904; GO:0030216; GO:0030326; GO:0030425; GO:0030850; GO:0030855; GO:0030859; GO:0031069; GO:0032991; GO:0033147; GO:0035115; GO:0035116; GO:0036342; GO:0042475; GO:0042771; GO:0042802; GO:0043005; GO:0043281; GO:0043565; GO:0043589; GO:0043616; GO:0045617; GO:0045669; GO:0045747; GO:0045892; GO:0045893; GO:0045944; GO:0046872; GO:0048485; GO:0048646; GO:0048807; GO:0048863; GO:0050699; GO:0051262; GO:0051402; GO:0060197; GO:0060513; GO:0060529; GO:0061436; GO:0072089; GO:0090398; GO:0097371; GO:0098773; GO:1902808; GO:1904674; GO:1904888; GO:2000271; GO:2000381; GO:2000648; GO:2000773; GO:2001235 16068 XR_006397467.1 3 0 8 0 54 NA NA NA NA NA NA 16069 XM_044325975.1 11 17 0 14 13 P22756 1.36e-70 Glutamate receptor ionotropic, kainate 1 (GluK1) (Glutamate receptor 5) (GluR-5) (GluR5) Rattus norvegicus (Rat) adult behavior [GO:0030534]; behavioral response to pain [GO:0048266]; chemical synaptic transmission [GO:0007268]; establishment of localization in cell [GO:0051649]; excitatory postsynaptic potential [GO:0060079]; gamma-aminobutyric acid secretion [GO:0014051]; inhibitory postsynaptic potential [GO:0060080]; ionotropic glutamate receptor signaling pathway [GO:0035235]; membrane depolarization [GO:0051899]; modulation of chemical synaptic transmission [GO:0050804]; modulation of excitatory postsynaptic potential [GO:0098815]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of gamma-aminobutyric acid secretion [GO:0014054]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; potassium ion transmembrane transport [GO:0071805]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of membrane potential [GO:0042391]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; sodium ion transmembrane transport [GO:0035725]; synaptic transmission, GABAergic [GO:0051932]; synaptic transmission, glutamatergic [GO:0035249] GO:0000149; GO:0004970; GO:0005234; GO:0005313; GO:0005886; GO:0007268; GO:0007399; GO:0008066; GO:0008328; GO:0014051; GO:0014054; GO:0014069; GO:0015276; GO:0015277; GO:0016020; GO:0016595; GO:0030425; GO:0030534; GO:0032229; GO:0032230; GO:0032983; GO:0035235; GO:0035249; GO:0035725; GO:0038023; GO:0042391; GO:0042734; GO:0042802; GO:0043025; GO:0043195; GO:0043235; GO:0045202; GO:0045211; GO:0048167; GO:0048172; GO:0048266; GO:0050804; GO:0051649; GO:0051899; GO:0051932; GO:0051967; GO:0060079; GO:0060080; GO:0071805; GO:0097110; GO:0098815; GO:0098978; GO:0099171; GO:0099507; GO:1904315 16070 XM_029356387.2 136 170 64 37 33 Q99MB5 9.26e-53 LIM domain only protein 3 (LMO-3) (Neuronal-specific transcription factor DAT1) Rattus norvegicus (Rat) negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of T cell homeostatic proliferation [GO:0046013] GO:0000122; GO:0003713; GO:0005634; GO:0045944; GO:0046013; GO:0046872; GO:0140297 16071 XM_044310285.1 0 0 11 8 3 NA NA NA NA NA NA 16072 XR_006393633.1 21 5 17 42 65 NA NA NA NA NA NA 16073 XM_044327835.1 11 0 0 0 0 NA NA NA NA NA NA 16074 XR_006394623.1 633 617 354 441 554 Q8IY21 0 Probable ATP-dependent RNA helicase DDX60 (EC 3.6.4.13) (DEAD box protein 60) Homo sapiens (Human) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; response to virus [GO:0009615] GO:0003690; GO:0003724; GO:0003725; GO:0003727; GO:0005524; GO:0005737; GO:0005829; GO:0009615; GO:0016887; GO:0045087; GO:0045111; GO:0051607; GO:1900245; GO:1900246 16075 XM_044320311.1 0 0 47 0 0 Q9JLB4 1.89e-70 Cubilin (Intrinsic factor-cobalamin receptor) Mus musculus (Mouse) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006898; GO:0007584; GO:0008203; GO:0009617; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 16076 XM_044320311.1 0 0 47 0 0 Q9JLB4 1.43e-59 Cubilin (Intrinsic factor-cobalamin receptor) Mus musculus (Mouse) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006898; GO:0007584; GO:0008203; GO:0009617; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 16077 XM_044320311.1 0 0 47 0 0 Q9JLB4 2.23e-58 Cubilin (Intrinsic factor-cobalamin receptor) Mus musculus (Mouse) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006898; GO:0007584; GO:0008203; GO:0009617; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 16078 XM_044320311.1 0 0 47 0 0 Q9JLB4 1.48e-56 Cubilin (Intrinsic factor-cobalamin receptor) Mus musculus (Mouse) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006898; GO:0007584; GO:0008203; GO:0009617; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 16079 XM_044320311.1 0 0 47 0 0 Q9JLB4 1.2e-53 Cubilin (Intrinsic factor-cobalamin receptor) Mus musculus (Mouse) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006898; GO:0007584; GO:0008203; GO:0009617; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 16080 XM_044320311.1 0 0 47 0 0 Q9JLB4 9.04e-48 Cubilin (Intrinsic factor-cobalamin receptor) Mus musculus (Mouse) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006898; GO:0007584; GO:0008203; GO:0009617; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 16081 XM_044320311.1 0 0 47 0 0 Q9JLB4 1.38e-47 Cubilin (Intrinsic factor-cobalamin receptor) Mus musculus (Mouse) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006898; GO:0007584; GO:0008203; GO:0009617; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 16082 XM_044327485.1 8995 9014 7932 10815 6643 Q9D1Q6 6.78e-141 Endoplasmic reticulum resident protein 44 (ER protein 44) (ERp44) (Thioredoxin domain-containing protein 4) Mus musculus (Mouse) glycoprotein metabolic process [GO:0009100]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976]; response to unfolded protein [GO:0006986] GO:0003756; GO:0005788; GO:0005789; GO:0005793; GO:0006457; GO:0006986; GO:0009100; GO:0009986; GO:0034976 16083 XM_029340641.2 18 9 5 24 41 NA NA NA NA NA NA 16084 XM_044312859.1 23 0 27 28 9 O88451 7.05e-82 Retinol dehydrogenase 7 (EC 1.1.1.105) (Cis-retinol/3alpha-hydroxysterol short-chain dehydrogenase isozyme 2) (Cis-retinol/androgen dehydrogenase type 2) (CRAD-2) Mus musculus (Mouse) retinol metabolic process [GO:0042572]; steroid metabolic process [GO:0008202] GO:0003824; GO:0004745; GO:0005783; GO:0008202; GO:0016491; GO:0042572; GO:0043231; GO:0047023; GO:0047044 16085 XR_006394384.1 0 99 0 19 23 NA NA NA NA NA NA 16086 XM_044313217.1 54 60 15 58 158 NA NA NA NA NA NA 16087 XM_044311874.1 21 12 22 39 45 NA NA NA NA NA NA 16088 XR_006394403.1 11 0 0 0 9 NA NA NA NA NA NA 16089 XM_044325294.1 23 259 232 173 354 NA NA NA NA NA NA 16090 XM_044327982.1 27 0 46 6 30 NA NA NA NA NA NA 16091 XM_044308728.1 4 8 17 16 84 NA NA NA NA NA NA 16092 XR_006397283.1 78 38 24 62 65 NA NA NA NA NA NA 16093 XM_029339356.2 409 0 0 265 816 Q0P4F7 0 Medium-chain acyl-CoA ligase ACSF2, mitochondrial (EC 6.2.1.2) Danio rerio (Zebrafish) (Brachydanio rerio) fatty acid metabolic process [GO:0006631] GO:0005524; GO:0005739; GO:0006631; GO:0031956; GO:0047760 16094 XM_029336351.2 0 26 0 169 0 NA NA NA NA NA NA 16095 XM_029337262.2 5989 6990 4029 9719 11945 O18728 3.59e-113 Fascin-2 (Retinal fascin) Bos taurus (Bovine) actin cytoskeleton organization [GO:0030036]; actin filament bundle assembly [GO:0051017]; cell migration [GO:0016477]; establishment or maintenance of cell polarity [GO:0007163]; eye photoreceptor cell development [GO:0042462] GO:0003779; GO:0005737; GO:0007163; GO:0015629; GO:0016477; GO:0030036; GO:0030674; GO:0032420; GO:0042462; GO:0051015; GO:0051017 16096 XM_029341905.2 63 60 43 53 96 NA NA NA NA NA NA 16097 XR_006394103.1 160 95 171 145 493 NA NA NA NA NA NA 16098 XM_044326580.1 1 0 0 15 1 NA NA NA NA NA NA 16099 XM_029342423.2 109 34 96 77 135 Q8HZ57 3.15e-34 Coiled-coil alpha-helical rod protein 1 (Alpha-helical coiled-coil rod protein) Pan paniscus (Pygmy chimpanzee) (Bonobo) cell differentiation [GO:0030154] GO:0005634; GO:0005737; GO:0005814; GO:0030154 16100 XM_044329050.1 2547 1085 1347 1538 1735 NA NA NA NA NA NA 16101 XM_029345155.2 1202 1763 295 330 716 Q5ZL74 2.78e-90 Vesicle-associated membrane protein 7 (Synaptobrevin-like protein 1) Gallus gallus (Chicken) calcium-ion regulated exocytosis [GO:0017156]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endosome to lysosome transport [GO:0008333]; eosinophil degranulation [GO:0043308]; exocytosis [GO:0006887]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; protein transport [GO:0015031]; vesicle fusion [GO:0006906]; vesicle-mediated transport [GO:0016192] GO:0000149; GO:0005484; GO:0005765; GO:0005789; GO:0005794; GO:0006887; GO:0006888; GO:0006906; GO:0006911; GO:0008333; GO:0015031; GO:0016192; GO:0017156; GO:0030658; GO:0030670; GO:0031201; GO:0031902; GO:0043005; GO:0043308; GO:0043312; GO:0045202; GO:0045335 16102 XM_044318758.1 2150 1207 551 2836 408 P52826 0 Carnitine O-acetyltransferase (Carnitine acetylase) (EC 2.3.1.137) (EC 2.3.1.7) (Carnitine acetyltransferase) (CAT) (CrAT) Columba livia (Rock dove) carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; medium-chain fatty acid metabolic process [GO:0051791]; short-chain fatty acid metabolic process [GO:0046459] GO:0003997; GO:0004092; GO:0005743; GO:0005777; GO:0005783; GO:0008458; GO:0019254; GO:0033540; GO:0046459; GO:0051791 16103 XM_029330679.2 4679 7172 3261 5337 4522 Q9DAN9 1.64e-27 Sperm axonemal maintenance protein CFAP97D1 (CFAP97 domain-containing protein 1) Mus musculus (Mouse) sperm axoneme assembly [GO:0007288] GO:0007288 16104 XM_044323519.1 27 31 29 17 16 Q3MQ06 6.34e-102 Autophagy protein 5 Rattus norvegicus (Rat) aggrephagy [GO:0035973]; antigen processing and presentation of endogenous antigen [GO:0019883]; apoptotic process [GO:0006915]; autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; autophagy of nucleus [GO:0044804]; blood vessel remodeling [GO:0001974]; C-terminal protein lipidation [GO:0006501]; cardiac muscle cell apoptotic process [GO:0010659]; cellular response to nitrogen starvation [GO:0006995]; cellular response to nitrosative stress [GO:0071500]; cellular response to starvation [GO:0009267]; chaperone-mediated autophagy [GO:0061684]; establishment of localization in cell [GO:0051649]; heart contraction [GO:0060047]; macroautophagy [GO:0016236]; mucus secretion [GO:0070254]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of cell death [GO:0060548]; negative regulation of defense response to virus [GO:0050687]; negative regulation of histone H4-K16 acetylation [GO:2000619]; negative regulation of innate immune response [GO:0045824]; negative regulation of phagocytosis [GO:0050765]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of type I interferon production [GO:0032480]; negative stranded viral RNA replication [GO:0039689]; negative thymic T cell selection [GO:0045060]; otolith development [GO:0048840]; positive regulation of mucus secretion [GO:0070257]; positive regulation of viral translation [GO:1904973]; post-translational protein modification [GO:0043687]; protein lipidation [GO:0006497]; protein lipidation involved in autophagosome assembly [GO:0061739]; protein ubiquitination [GO:0016567]; regulation of autophagosome maturation [GO:1901096]; regulation of cilium assembly [GO:1902017]; regulation of cytokine production involved in immune response [GO:0002718]; regulation of reactive oxygen species metabolic process [GO:2000377]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; response to fluoride [GO:1902617]; response to fungus [GO:0009620]; response to iron(II) ion [GO:0010040]; response to xenobiotic stimulus [GO:0009410]; vasodilation [GO:0042311]; ventricular cardiac muscle cell development [GO:0055015] GO:0000045; GO:0000422; GO:0001974; GO:0002718; GO:0005737; GO:0005776; GO:0005930; GO:0006497; GO:0006501; GO:0006914; GO:0006915; GO:0006995; GO:0009267; GO:0009410; GO:0009620; GO:0010040; GO:0010659; GO:0010667; GO:0016020; GO:0016236; GO:0016567; GO:0019883; GO:0030424; GO:0031397; GO:0032480; GO:0032991; GO:0034045; GO:0034274; GO:0035973; GO:0039689; GO:0042311; GO:0043066; GO:0043687; GO:0044233; GO:0044804; GO:0045060; GO:0045824; GO:0048840; GO:0050687; GO:0050765; GO:0051279; GO:0051649; GO:0055015; GO:0060047; GO:0060548; GO:0061684; GO:0061739; GO:0070254; GO:0070257; GO:0071500; GO:1901096; GO:1902017; GO:1902617; GO:1904973; GO:1990234; GO:2000377; GO:2000378; GO:2000619 16105 XM_029338268.2 1161 746 655 1249 1130 A7E2V4 5.22e-37 Zinc finger SWIM domain-containing protein 8 Homo sapiens (Human) positive regulation of miRNA catabolic process [GO:2000627]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567] GO:0005829; GO:0008270; GO:0016567; GO:0031462; GO:0031463; GO:0043161; GO:1990756; GO:2000627 16106 XM_044307809.1 56 37 0 0 13 NA NA NA NA NA NA 16107 XM_029331248.2 53 0 0 22 4 Q96D71 1.09e-25 RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1) Homo sapiens (Human) endocytosis [GO:0006897]; endosomal transport [GO:0016197] GO:0005509; GO:0005829; GO:0005886; GO:0005905; GO:0006897; GO:0016197; GO:0017124 16108 XM_029340769.2 576 242 47 159 40 NA NA NA NA NA NA 16109 XM_029347630.2 1867 2454 1845 1407 1232 B3CRZ0 5.85e-33 50S ribosomal protein L20 Orientia tsutsugamushi (strain Ikeda) (Rickettsia tsutsugamushi) ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412] GO:0000027; GO:0003735; GO:0005840; GO:0006412; GO:0019843; GO:1990904 16110 XM_029347533.2 377 351 240 365 655 NA NA NA NA NA NA 16111 XM_044326412.1 448 408 289 481 541 A6QP15 0 Hydroxyacid-oxoacid transhydrogenase, mitochondrial (HOT) (EC 1.1.99.24) (Alcohol dehydrogenase iron-containing protein 1) (ADHFe1) Bos taurus (Bovine) glutamate catabolic process via 2-oxoglutarate [GO:0006539]; lipid metabolic process [GO:0006629] GO:0004022; GO:0005739; GO:0006539; GO:0006629; GO:0046872; GO:0047988 16112 XM_044321384.1 783 147 9 590 284 Q2PZL6 0 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 16113 XM_044321384.1 783 147 9 590 284 Q2PZL6 0 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 16114 XM_044321384.1 783 147 9 590 284 Q2PZL6 0 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 16115 XM_044321384.1 783 147 9 590 284 Q2PZL6 0 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 16116 XM_044321384.1 783 147 9 590 284 Q2PZL6 0 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 16117 XM_044321384.1 783 147 9 590 284 Q2PZL6 0 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 16118 XM_044321384.1 783 147 9 590 284 Q2PZL6 0 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 16119 XM_044321384.1 783 147 9 590 284 Q2PZL6 0 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 16120 XM_044321384.1 783 147 9 590 284 Q2PZL6 0 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 16121 XM_029345005.2 111 72 66 73 142 NA NA NA NA NA NA 16122 XM_029357289.1 14833 14350 10752 14910 10033 P62268 5.74e-94 40S ribosomal protein S23 Rattus norvegicus (Rat) cytoplasmic translation [GO:0002181]; maintenance of translational fidelity [GO:1990145]; stress granule assembly [GO:0034063]; translation [GO:0006412] GO:0002181; GO:0003735; GO:0005791; GO:0005840; GO:0006412; GO:0015935; GO:0022626; GO:0022627; GO:0034063; GO:0042788; GO:0045182; GO:0045202; GO:1990145 16123 XM_044307203.1 308 194 122 141 212 Q63HM2 0 Pecanex-like protein 4 (Hepatitis C virus F protein-binding protein 2) (HCV F protein-binding protein 2) (Pecanex homolog protein 4) Homo sapiens (Human) NA GO:0016020 16124 XM_044309018.1 6 5 21 6 29 Q99315 1.75e-64 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 16125 XR_006396923.1 0 0 2 14 31 NA NA NA NA NA NA 16126 XM_044324526.1 69 90 77 43 70 NA NA NA NA NA NA 16127 XM_044306974.1 119 0 0 108 0 A6PWV5 3.29e-67 AT-rich interactive domain-containing protein 3C (ARID domain-containing protein 3C) Mus musculus (Mouse) positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0003677; GO:0003682; GO:0005634; GO:0005737; GO:0006357; GO:0045121; GO:0045944 16128 XR_006395864.1 768 382 382 490 465 NA NA NA NA NA NA 16129 XR_006394199.1 550 119 47 235 332 P21127 1.01e-23 Cyclin-dependent kinase 11B (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 1) (CLK-1) (Cell division protein kinase 11B) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L1) (p58 CLK-1) Homo sapiens (Human) apoptotic process [GO:0006915]; mitotic cell cycle [GO:0000278]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell growth [GO:0001558]; regulation of centrosome cycle [GO:0046605]; regulation of DNA-templated transcription [GO:0006355]; regulation of mitotic cell cycle [GO:0007346]; regulation of mRNA processing [GO:0050684]; regulation of RNA splicing [GO:0043484] GO:0000278; GO:0000307; GO:0001558; GO:0003723; GO:0004672; GO:0004674; GO:0004693; GO:0005524; GO:0005634; GO:0005737; GO:0006355; GO:0006468; GO:0006915; GO:0007346; GO:0042981; GO:0043484; GO:0046605; GO:0050684; GO:0051726; GO:0106310 16130 XM_029330374.2 5492 4243 2741 6929 7112 P45953 0 Very long-chain specific acyl-CoA dehydrogenase, mitochondrial (VLCAD) (EC 1.3.8.9) Rattus norvegicus (Rat) epithelial cell differentiation [GO:0030855]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; fatty acid catabolic process [GO:0009062]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of fatty acid oxidation [GO:0046322]; regulation of cholesterol metabolic process [GO:0090181]; response to cold [GO:0009409]; temperature homeostasis [GO:0001659] GO:0000062; GO:0001659; GO:0003995; GO:0004466; GO:0005739; GO:0005743; GO:0006635; GO:0009062; GO:0009409; GO:0017099; GO:0030855; GO:0031314; GO:0031966; GO:0033539; GO:0042645; GO:0042802; GO:0045717; GO:0046322; GO:0050660; GO:0090181 16131 XM_044315988.1 0 0 74 0 0 A3KN83 0 Protein strawberry notch homolog 1 (Monocyte protein 3) (MOP-3) Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355]; regulation of response to stimulus [GO:0048583] GO:0005634; GO:0006355; GO:0031490; GO:0042393; GO:0048583 16132 XM_029351350.2 31 36 0 0 0 Q6NS23 2.61e-136 tRNA (guanine(10)-N2)-methyltransferase homolog (EC 2.1.1.-) (tRNA guanosine-2'-O-methyltransferase TRM11 homolog) Xenopus laevis (African clawed frog) RNA methylation [GO:0001510]; tRNA processing [GO:0008033] GO:0000049; GO:0001510; GO:0008033; GO:0008168 16133 XM_029325985.2 16 4 14 62 27 Q80XJ3 7.93e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 16134 XM_029338563.2 1889 2035 1416 1596 1848 Q5ZL33 1.09e-142 Serine-threonine kinase receptor-associated protein Gallus gallus (Chicken) alternative mRNA splicing, via spliceosome [GO:0000380]; maintenance of gastrointestinal epithelium [GO:0030277]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron differentiation [GO:0030182]; spliceosomal snRNP assembly [GO:0000387] GO:0000122; GO:0000380; GO:0000387; GO:0003729; GO:0004857; GO:0005102; GO:0005634; GO:0005829; GO:0030182; GO:0030277; GO:0030512; GO:0032797; GO:0034719; GO:0140416; GO:1990447 16135 XM_029331722.2 1482 1138 660 1199 1013 P18850 1.32e-22 Cyclic AMP-dependent transcription factor ATF-6 alpha (cAMP-dependent transcription factor ATF-6 alpha) (Activating transcription factor 6 alpha) (ATF6-alpha) [Cleaved into: Processed cyclic AMP-dependent transcription factor ATF-6 alpha] Homo sapiens (Human) ATF6-mediated unfolded protein response [GO:0036500]; endoplasmic reticulum unfolded protein response [GO:0030968]; ERAD pathway [GO:0036503]; eye development [GO:0001654]; positive regulation of apoptotic process [GO:0043065]; positive regulation of ATF6-mediated unfolded protein response [GO:1903893]; positive regulation of autophagy [GO:0010508]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; protein folding [GO:0006457]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; visual perception [GO:0007601] GO:0000139; GO:0000785; GO:0000976; GO:0000977; GO:0000978; GO:0000981; GO:0001228; GO:0001654; GO:0003700; GO:0005634; GO:0005635; GO:0005654; GO:0005783; GO:0005789; GO:0005794; GO:0005829; GO:0006357; GO:0006457; GO:0007165; GO:0007601; GO:0010508; GO:0016020; GO:0030968; GO:0031625; GO:0036500; GO:0036503; GO:0042802; GO:0043065; GO:0043565; GO:0045944; GO:0046982; GO:0090575; GO:1903893; GO:1990440; GO:1990837 16136 XM_029336967.2 675 313 275 578 501 NA NA NA NA NA NA 16137 XM_044322398.1 330 92 94 257 153 Q96AY4 5.49e-94 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16138 XM_044322398.1 330 92 94 257 153 Q96AY4 2.27e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16139 XM_044322398.1 330 92 94 257 153 Q96AY4 2.53e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16140 XM_044322398.1 330 92 94 257 153 Q96AY4 2.04e-83 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16141 XM_044322398.1 330 92 94 257 153 Q96AY4 3.89e-83 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16142 XM_044322398.1 330 92 94 257 153 Q96AY4 8.99e-82 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16143 XM_044322398.1 330 92 94 257 153 Q96AY4 1.94e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16144 XM_044313888.1 7 2 3 0 12 NA NA NA NA NA NA 16145 XM_044318389.1 25 3 40 11 4 NA NA NA NA NA NA 16146 XM_044317864.1 0 0 28 45 140 NA NA NA NA NA NA 16147 XM_044320462.1 821 910 608 955 875 Q04656 0 Copper-transporting ATPase 1 (EC 7.2.2.8) (Copper pump 1) (Menkes disease-associated protein) Homo sapiens (Human) blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cartilage development [GO:0051216]; catecholamine metabolic process [GO:0006584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amino acid stimulus [GO:0071230]; cellular response to antibiotic [GO:0071236]; cellular response to cadmium ion [GO:0071276]; cellular response to cobalt ion [GO:0071279]; cellular response to copper ion [GO:0071280]; cellular response to hypoxia [GO:0071456]; cellular response to iron ion [GO:0071281]; cellular response to lead ion [GO:0071284]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; central nervous system neuron development [GO:0021954]; cerebellar Purkinje cell differentiation [GO:0021702]; collagen fibril organization [GO:0030199]; copper ion export [GO:0060003]; copper ion homeostasis [GO:0055070]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; detoxification of copper ion [GO:0010273]; dopamine metabolic process [GO:0042417]; elastic fiber assembly [GO:0048251]; elastin biosynthetic process [GO:0051542]; epinephrine metabolic process [GO:0042414]; extracellular matrix organization [GO:0030198]; female pregnancy [GO:0007565]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; lactation [GO:0007595]; liver development [GO:0001889]; locomotory behavior [GO:0007626]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; negative regulation of iron ion transmembrane transport [GO:0034760]; neuron projection morphogenesis [GO:0048812]; norepinephrine metabolic process [GO:0042415]; peptidyl-lysine modification [GO:0018205]; pigmentation [GO:0043473]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell size [GO:0045793]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of response to wounding [GO:1903036]; positive regulation of tyrosinase activity [GO:0032773]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; pyramidal neuron development [GO:0021860]; regulation of cytochrome-c oxidase activity [GO:1904959]; regulation of gene expression [GO:0010468]; regulation of oxidative phosphorylation [GO:0002082]; removal of superoxide radicals [GO:0019430]; response to iron(III) ion [GO:0010041]; response to manganese ion [GO:0010042]; response to zinc ion [GO:0010043]; serotonin metabolic process [GO:0042428]; skin development [GO:0043588]; T-helper cell differentiation [GO:0042093]; tryptophan metabolic process [GO:0006568] GO:0001568; GO:0001701; GO:0001889; GO:0001974; GO:0002082; GO:0005375; GO:0005507; GO:0005524; GO:0005634; GO:0005770; GO:0005783; GO:0005794; GO:0005802; GO:0005829; GO:0005886; GO:0005902; GO:0006568; GO:0006584; GO:0006825; GO:0006878; GO:0007005; GO:0007565; GO:0007595; GO:0007626; GO:0010041; GO:0010042; GO:0010043; GO:0010273; GO:0010468; GO:0010592; GO:0014069; GO:0015677; GO:0016020; GO:0016323; GO:0016324; GO:0016532; GO:0016887; GO:0018205; GO:0019430; GO:0021702; GO:0021860; GO:0021954; GO:0030140; GO:0030141; GO:0030198; GO:0030199; GO:0030424; GO:0030425; GO:0030670; GO:0031069; GO:0031252; GO:0031267; GO:0031526; GO:0031901; GO:0032588; GO:0032767; GO:0032773; GO:0033162; GO:0034760; GO:0036120; GO:0042093; GO:0042414; GO:0042415; GO:0042417; GO:0042428; GO:0043005; GO:0043025; GO:0043085; GO:0043204; GO:0043473; GO:0043588; GO:0043682; GO:0045121; GO:0045793; GO:0048023; GO:0048251; GO:0048286; GO:0048471; GO:0048812; GO:0050679; GO:0051087; GO:0051216; GO:0051542; GO:0055070; GO:0060003; GO:0071230; GO:0071236; GO:0071276; GO:0071279; GO:0071280; GO:0071281; GO:0071284; GO:0071456; GO:0140581; GO:1903036; GO:1903136; GO:1904754; GO:1904959 16148 XM_044320462.1 821 910 608 955 875 Q04656 1.68e-47 Copper-transporting ATPase 1 (EC 7.2.2.8) (Copper pump 1) (Menkes disease-associated protein) Homo sapiens (Human) blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cartilage development [GO:0051216]; catecholamine metabolic process [GO:0006584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amino acid stimulus [GO:0071230]; cellular response to antibiotic [GO:0071236]; cellular response to cadmium ion [GO:0071276]; cellular response to cobalt ion [GO:0071279]; cellular response to copper ion [GO:0071280]; cellular response to hypoxia [GO:0071456]; cellular response to iron ion [GO:0071281]; cellular response to lead ion [GO:0071284]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; central nervous system neuron development [GO:0021954]; cerebellar Purkinje cell differentiation [GO:0021702]; collagen fibril organization [GO:0030199]; copper ion export [GO:0060003]; copper ion homeostasis [GO:0055070]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; detoxification of copper ion [GO:0010273]; dopamine metabolic process [GO:0042417]; elastic fiber assembly [GO:0048251]; elastin biosynthetic process [GO:0051542]; epinephrine metabolic process [GO:0042414]; extracellular matrix organization [GO:0030198]; female pregnancy [GO:0007565]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; lactation [GO:0007595]; liver development [GO:0001889]; locomotory behavior [GO:0007626]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; negative regulation of iron ion transmembrane transport [GO:0034760]; neuron projection morphogenesis [GO:0048812]; norepinephrine metabolic process [GO:0042415]; peptidyl-lysine modification [GO:0018205]; pigmentation [GO:0043473]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell size [GO:0045793]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of response to wounding [GO:1903036]; positive regulation of tyrosinase activity [GO:0032773]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; pyramidal neuron development [GO:0021860]; regulation of cytochrome-c oxidase activity [GO:1904959]; regulation of gene expression [GO:0010468]; regulation of oxidative phosphorylation [GO:0002082]; removal of superoxide radicals [GO:0019430]; response to iron(III) ion [GO:0010041]; response to manganese ion [GO:0010042]; response to zinc ion [GO:0010043]; serotonin metabolic process [GO:0042428]; skin development [GO:0043588]; T-helper cell differentiation [GO:0042093]; tryptophan metabolic process [GO:0006568] GO:0001568; GO:0001701; GO:0001889; GO:0001974; GO:0002082; GO:0005375; GO:0005507; GO:0005524; GO:0005634; GO:0005770; GO:0005783; GO:0005794; GO:0005802; GO:0005829; GO:0005886; GO:0005902; GO:0006568; GO:0006584; GO:0006825; GO:0006878; GO:0007005; GO:0007565; GO:0007595; GO:0007626; GO:0010041; GO:0010042; GO:0010043; GO:0010273; GO:0010468; GO:0010592; GO:0014069; GO:0015677; GO:0016020; GO:0016323; GO:0016324; GO:0016532; GO:0016887; GO:0018205; GO:0019430; GO:0021702; GO:0021860; GO:0021954; GO:0030140; GO:0030141; GO:0030198; GO:0030199; GO:0030424; GO:0030425; GO:0030670; GO:0031069; GO:0031252; GO:0031267; GO:0031526; GO:0031901; GO:0032588; GO:0032767; GO:0032773; GO:0033162; GO:0034760; GO:0036120; GO:0042093; GO:0042414; GO:0042415; GO:0042417; GO:0042428; GO:0043005; GO:0043025; GO:0043085; GO:0043204; GO:0043473; GO:0043588; GO:0043682; GO:0045121; GO:0045793; GO:0048023; GO:0048251; GO:0048286; GO:0048471; GO:0048812; GO:0050679; GO:0051087; GO:0051216; GO:0051542; GO:0055070; GO:0060003; GO:0071230; GO:0071236; GO:0071276; GO:0071279; GO:0071280; GO:0071281; GO:0071284; GO:0071456; GO:0140581; GO:1903036; GO:1903136; GO:1904754; GO:1904959 16149 XM_044320462.1 821 910 608 955 875 Q04656 4.62e-44 Copper-transporting ATPase 1 (EC 7.2.2.8) (Copper pump 1) (Menkes disease-associated protein) Homo sapiens (Human) blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cartilage development [GO:0051216]; catecholamine metabolic process [GO:0006584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amino acid stimulus [GO:0071230]; cellular response to antibiotic [GO:0071236]; cellular response to cadmium ion [GO:0071276]; cellular response to cobalt ion [GO:0071279]; cellular response to copper ion [GO:0071280]; cellular response to hypoxia [GO:0071456]; cellular response to iron ion [GO:0071281]; cellular response to lead ion [GO:0071284]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; central nervous system neuron development [GO:0021954]; cerebellar Purkinje cell differentiation [GO:0021702]; collagen fibril organization [GO:0030199]; copper ion export [GO:0060003]; copper ion homeostasis [GO:0055070]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; detoxification of copper ion [GO:0010273]; dopamine metabolic process [GO:0042417]; elastic fiber assembly [GO:0048251]; elastin biosynthetic process [GO:0051542]; epinephrine metabolic process [GO:0042414]; extracellular matrix organization [GO:0030198]; female pregnancy [GO:0007565]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; lactation [GO:0007595]; liver development [GO:0001889]; locomotory behavior [GO:0007626]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; negative regulation of iron ion transmembrane transport [GO:0034760]; neuron projection morphogenesis [GO:0048812]; norepinephrine metabolic process [GO:0042415]; peptidyl-lysine modification [GO:0018205]; pigmentation [GO:0043473]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell size [GO:0045793]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of response to wounding [GO:1903036]; positive regulation of tyrosinase activity [GO:0032773]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; pyramidal neuron development [GO:0021860]; regulation of cytochrome-c oxidase activity [GO:1904959]; regulation of gene expression [GO:0010468]; regulation of oxidative phosphorylation [GO:0002082]; removal of superoxide radicals [GO:0019430]; response to iron(III) ion [GO:0010041]; response to manganese ion [GO:0010042]; response to zinc ion [GO:0010043]; serotonin metabolic process [GO:0042428]; skin development [GO:0043588]; T-helper cell differentiation [GO:0042093]; tryptophan metabolic process [GO:0006568] GO:0001568; GO:0001701; GO:0001889; GO:0001974; GO:0002082; GO:0005375; GO:0005507; GO:0005524; GO:0005634; GO:0005770; GO:0005783; GO:0005794; GO:0005802; GO:0005829; GO:0005886; GO:0005902; GO:0006568; GO:0006584; GO:0006825; GO:0006878; GO:0007005; GO:0007565; GO:0007595; GO:0007626; GO:0010041; GO:0010042; GO:0010043; GO:0010273; GO:0010468; GO:0010592; GO:0014069; GO:0015677; GO:0016020; GO:0016323; GO:0016324; GO:0016532; GO:0016887; GO:0018205; GO:0019430; GO:0021702; GO:0021860; GO:0021954; GO:0030140; GO:0030141; GO:0030198; GO:0030199; GO:0030424; GO:0030425; GO:0030670; GO:0031069; GO:0031252; GO:0031267; GO:0031526; GO:0031901; GO:0032588; GO:0032767; GO:0032773; GO:0033162; GO:0034760; GO:0036120; GO:0042093; GO:0042414; GO:0042415; GO:0042417; GO:0042428; GO:0043005; GO:0043025; GO:0043085; GO:0043204; GO:0043473; GO:0043588; GO:0043682; GO:0045121; GO:0045793; GO:0048023; GO:0048251; GO:0048286; GO:0048471; GO:0048812; GO:0050679; GO:0051087; GO:0051216; GO:0051542; GO:0055070; GO:0060003; GO:0071230; GO:0071236; GO:0071276; GO:0071279; GO:0071280; GO:0071281; GO:0071284; GO:0071456; GO:0140581; GO:1903036; GO:1903136; GO:1904754; GO:1904959 16150 XM_044320462.1 821 910 608 955 875 Q04656 3.22e-42 Copper-transporting ATPase 1 (EC 7.2.2.8) (Copper pump 1) (Menkes disease-associated protein) Homo sapiens (Human) blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cartilage development [GO:0051216]; catecholamine metabolic process [GO:0006584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amino acid stimulus [GO:0071230]; cellular response to antibiotic [GO:0071236]; cellular response to cadmium ion [GO:0071276]; cellular response to cobalt ion [GO:0071279]; cellular response to copper ion [GO:0071280]; cellular response to hypoxia [GO:0071456]; cellular response to iron ion [GO:0071281]; cellular response to lead ion [GO:0071284]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; central nervous system neuron development [GO:0021954]; cerebellar Purkinje cell differentiation [GO:0021702]; collagen fibril organization [GO:0030199]; copper ion export [GO:0060003]; copper ion homeostasis [GO:0055070]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; detoxification of copper ion [GO:0010273]; dopamine metabolic process [GO:0042417]; elastic fiber assembly [GO:0048251]; elastin biosynthetic process [GO:0051542]; epinephrine metabolic process [GO:0042414]; extracellular matrix organization [GO:0030198]; female pregnancy [GO:0007565]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; lactation [GO:0007595]; liver development [GO:0001889]; locomotory behavior [GO:0007626]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; negative regulation of iron ion transmembrane transport [GO:0034760]; neuron projection morphogenesis [GO:0048812]; norepinephrine metabolic process [GO:0042415]; peptidyl-lysine modification [GO:0018205]; pigmentation [GO:0043473]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell size [GO:0045793]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of response to wounding [GO:1903036]; positive regulation of tyrosinase activity [GO:0032773]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; pyramidal neuron development [GO:0021860]; regulation of cytochrome-c oxidase activity [GO:1904959]; regulation of gene expression [GO:0010468]; regulation of oxidative phosphorylation [GO:0002082]; removal of superoxide radicals [GO:0019430]; response to iron(III) ion [GO:0010041]; response to manganese ion [GO:0010042]; response to zinc ion [GO:0010043]; serotonin metabolic process [GO:0042428]; skin development [GO:0043588]; T-helper cell differentiation [GO:0042093]; tryptophan metabolic process [GO:0006568] GO:0001568; GO:0001701; GO:0001889; GO:0001974; GO:0002082; GO:0005375; GO:0005507; GO:0005524; GO:0005634; GO:0005770; GO:0005783; GO:0005794; GO:0005802; GO:0005829; GO:0005886; GO:0005902; GO:0006568; GO:0006584; GO:0006825; GO:0006878; GO:0007005; GO:0007565; GO:0007595; GO:0007626; GO:0010041; GO:0010042; GO:0010043; GO:0010273; GO:0010468; GO:0010592; GO:0014069; GO:0015677; GO:0016020; GO:0016323; GO:0016324; GO:0016532; GO:0016887; GO:0018205; GO:0019430; GO:0021702; GO:0021860; GO:0021954; GO:0030140; GO:0030141; GO:0030198; GO:0030199; GO:0030424; GO:0030425; GO:0030670; GO:0031069; GO:0031252; GO:0031267; GO:0031526; GO:0031901; GO:0032588; GO:0032767; GO:0032773; GO:0033162; GO:0034760; GO:0036120; GO:0042093; GO:0042414; GO:0042415; GO:0042417; GO:0042428; GO:0043005; GO:0043025; GO:0043085; GO:0043204; GO:0043473; GO:0043588; GO:0043682; GO:0045121; GO:0045793; GO:0048023; GO:0048251; GO:0048286; GO:0048471; GO:0048812; GO:0050679; GO:0051087; GO:0051216; GO:0051542; GO:0055070; GO:0060003; GO:0071230; GO:0071236; GO:0071276; GO:0071279; GO:0071280; GO:0071281; GO:0071284; GO:0071456; GO:0140581; GO:1903036; GO:1903136; GO:1904754; GO:1904959 16151 XM_044320462.1 821 910 608 955 875 Q04656 3.68e-32 Copper-transporting ATPase 1 (EC 7.2.2.8) (Copper pump 1) (Menkes disease-associated protein) Homo sapiens (Human) blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cartilage development [GO:0051216]; catecholamine metabolic process [GO:0006584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amino acid stimulus [GO:0071230]; cellular response to antibiotic [GO:0071236]; cellular response to cadmium ion [GO:0071276]; cellular response to cobalt ion [GO:0071279]; cellular response to copper ion [GO:0071280]; cellular response to hypoxia [GO:0071456]; cellular response to iron ion [GO:0071281]; cellular response to lead ion [GO:0071284]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; central nervous system neuron development [GO:0021954]; cerebellar Purkinje cell differentiation [GO:0021702]; collagen fibril organization [GO:0030199]; copper ion export [GO:0060003]; copper ion homeostasis [GO:0055070]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; detoxification of copper ion [GO:0010273]; dopamine metabolic process [GO:0042417]; elastic fiber assembly [GO:0048251]; elastin biosynthetic process [GO:0051542]; epinephrine metabolic process [GO:0042414]; extracellular matrix organization [GO:0030198]; female pregnancy [GO:0007565]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; lactation [GO:0007595]; liver development [GO:0001889]; locomotory behavior [GO:0007626]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; negative regulation of iron ion transmembrane transport [GO:0034760]; neuron projection morphogenesis [GO:0048812]; norepinephrine metabolic process [GO:0042415]; peptidyl-lysine modification [GO:0018205]; pigmentation [GO:0043473]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell size [GO:0045793]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of response to wounding [GO:1903036]; positive regulation of tyrosinase activity [GO:0032773]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; pyramidal neuron development [GO:0021860]; regulation of cytochrome-c oxidase activity [GO:1904959]; regulation of gene expression [GO:0010468]; regulation of oxidative phosphorylation [GO:0002082]; removal of superoxide radicals [GO:0019430]; response to iron(III) ion [GO:0010041]; response to manganese ion [GO:0010042]; response to zinc ion [GO:0010043]; serotonin metabolic process [GO:0042428]; skin development [GO:0043588]; T-helper cell differentiation [GO:0042093]; tryptophan metabolic process [GO:0006568] GO:0001568; GO:0001701; GO:0001889; GO:0001974; GO:0002082; GO:0005375; GO:0005507; GO:0005524; GO:0005634; GO:0005770; GO:0005783; GO:0005794; GO:0005802; GO:0005829; GO:0005886; GO:0005902; GO:0006568; GO:0006584; GO:0006825; GO:0006878; GO:0007005; GO:0007565; GO:0007595; GO:0007626; GO:0010041; GO:0010042; GO:0010043; GO:0010273; GO:0010468; GO:0010592; GO:0014069; GO:0015677; GO:0016020; GO:0016323; GO:0016324; GO:0016532; GO:0016887; GO:0018205; GO:0019430; GO:0021702; GO:0021860; GO:0021954; GO:0030140; GO:0030141; GO:0030198; GO:0030199; GO:0030424; GO:0030425; GO:0030670; GO:0031069; GO:0031252; GO:0031267; GO:0031526; GO:0031901; GO:0032588; GO:0032767; GO:0032773; GO:0033162; GO:0034760; GO:0036120; GO:0042093; GO:0042414; GO:0042415; GO:0042417; GO:0042428; GO:0043005; GO:0043025; GO:0043085; GO:0043204; GO:0043473; GO:0043588; GO:0043682; GO:0045121; GO:0045793; GO:0048023; GO:0048251; GO:0048286; GO:0048471; GO:0048812; GO:0050679; GO:0051087; GO:0051216; GO:0051542; GO:0055070; GO:0060003; GO:0071230; GO:0071236; GO:0071276; GO:0071279; GO:0071280; GO:0071281; GO:0071284; GO:0071456; GO:0140581; GO:1903036; GO:1903136; GO:1904754; GO:1904959 16152 XM_029333156.2 138 60 51 85 173 NA NA NA NA NA NA 16153 XM_044317307.1 12 14 4 30 3 A0A2B4SJA1 7.06e-110 NA NA NA NA 16154 XM_029338240.2 297 91 235 212 407 NA NA NA NA NA NA 16155 XM_044313941.1 29 0 23 1 27 B8VIU6 8.8e-61 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 16156 XR_003827581.2 0 763 0 0 13 NA NA NA NA NA NA 16157 XM_029353022.2 6688 4708 3021 4886 1635 Q6IQE0 9.84e-130 Poly(U)-binding-splicing factor PUF60-B Danio rerio (Zebrafish) (Brachydanio rerio) alternative mRNA splicing, via spliceosome [GO:0000380]; apoptotic process [GO:0006915]; mRNA splice site selection [GO:0006376]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381] GO:0000380; GO:0000381; GO:0003677; GO:0003723; GO:0005634; GO:0006376; GO:0006915; GO:1990904 16158 XM_044307299.1 14 4 12 5 50 NA NA NA NA NA NA 16159 XM_044311694.1 321 1125 442 1833 0 Q96T58 3.57e-62 Msx2-interacting protein (SMART/HDAC1-associated repressor protein) (SPEN homolog) Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of neurogenesis [GO:0050769]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0003677; GO:0003714; GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0006357; GO:0007219; GO:0017053; GO:0045892; GO:0050769; GO:0061629; GO:0070062 16160 XM_044311694.1 321 1125 442 1833 0 Q96T58 3.57e-59 Msx2-interacting protein (SMART/HDAC1-associated repressor protein) (SPEN homolog) Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of neurogenesis [GO:0050769]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0003677; GO:0003714; GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0006357; GO:0007219; GO:0017053; GO:0045892; GO:0050769; GO:0061629; GO:0070062 16161 XM_044311694.1 321 1125 442 1833 0 Q96T58 3.29e-35 Msx2-interacting protein (SMART/HDAC1-associated repressor protein) (SPEN homolog) Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of neurogenesis [GO:0050769]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0003677; GO:0003714; GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0006357; GO:0007219; GO:0017053; GO:0045892; GO:0050769; GO:0061629; GO:0070062 16162 XR_006394492.1 266 19 206 197 11 NA NA NA NA NA NA 16163 XM_029338793.2 345 293 214 330 458 Q6P616 9.23e-168 Pre-mRNA-splicing factor RBM22 (RNA-binding motif protein 22) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) mRNA cis splicing, via spliceosome [GO:0045292]; positive regulation of RNA splicing [GO:0033120] GO:0005634; GO:0005681; GO:0005737; GO:0017070; GO:0033120; GO:0036002; GO:0045292; GO:0046872 16164 XR_003823137.2 26 0 2 0 23 NA NA NA NA NA NA 16165 XR_006392705.1 59 40 40 23 21 NA NA NA NA NA NA 16166 XM_044309341.1 76 0 0 0 68 NA NA NA NA NA NA 16167 XR_006392455.1 373 125 227 268 440 Q99570 2.6e-82 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 16168 XR_006392455.1 373 125 227 268 440 Q99570 2.6e-82 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 16169 XM_044328178.1 110 180 35 119 37 Q6GMF8 2.19e-151 Inactive rhomboid protein 1 (iRhom1) (Rhomboid family member 1) Danio rerio (Zebrafish) (Brachydanio rerio) cell migration [GO:0016477]; cell population proliferation [GO:0008283]; negative regulation of protein secretion [GO:0050709]; protein transport [GO:0015031]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of protein secretion [GO:0050708] GO:0000139; GO:0005789; GO:0008283; GO:0015031; GO:0016477; GO:0019838; GO:0042058; GO:0050708; GO:0050709; GO:0061136 16170 XM_029352514.2 139 89 50 187 109 Q96AY4 2.66e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16171 XM_029352817.2 145 276 75 148 643 NA NA NA NA NA NA 16172 XM_029330774.2 314 264 193 245 295 Q08E31 1.07e-25 Calcium-responsive transactivator (SS18-like protein 1) Bos taurus (Bovine) chromatin organization [GO:0006325]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000776; GO:0003713; GO:0005634; GO:0006325; GO:0045893; GO:0045944; GO:0050775 16173 XM_044319172.1 170 148 77 345 107 O88917 4.21e-49 Adhesion G protein-coupled receptor L1 (Calcium-independent alpha-latrotoxin receptor 1) (CIRL-1) (Latrophilin-1) Rattus norvegicus (Rat) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; brain development [GO:0007420]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell surface receptor signaling pathway [GO:0007166]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synapse maturation [GO:0090129] GO:0004930; GO:0005886; GO:0007157; GO:0007166; GO:0007189; GO:0007420; GO:0014069; GO:0015643; GO:0016524; GO:0030246; GO:0030424; GO:0030426; GO:0035584; GO:0042734; GO:0043005; GO:0045202; GO:0050839; GO:0051965; GO:0090129; GO:0098978 16174 XM_029331409.2 801 356 561 1214 566 NA NA NA NA NA NA 16175 XM_029332635.2 756 422 343 390 291 Q9R1W3 1.46e-94 E3 ubiquitin-protein ligase RNF103 (EC 2.3.2.27) (KF-1) (mKF-1) (RING finger protein 103) (RING-type E3 ubiquitin transferase RNF103) (Zinc finger protein 103) (Zfp-103) Mus musculus (Mouse) protein ubiquitination [GO:0016567]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0004842; GO:0005783; GO:0005789; GO:0016567; GO:0030433; GO:0046872 16176 XM_029345888.2 5341 4689 3570 3941 2788 Q8HXQ3 6.42e-67 Superoxide dismutase [Cu-Zn] (EC 1.15.1.1) Hylobates lar (Common gibbon) (White-handed gibbon) auditory receptor cell stereocilium organization [GO:0060088]; cellular iron ion homeostasis [GO:0006879]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of MAPK cascade [GO:0043410]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular associated smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226] GO:0000303; GO:0001541; GO:0001819; GO:0001895; GO:0002262; GO:0004784; GO:0005507; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0006749; GO:0006801; GO:0006879; GO:0007283; GO:0007566; GO:0007605; GO:0007626; GO:0008217; GO:0008270; GO:0009408; GO:0010033; GO:0019226; GO:0019430; GO:0030346; GO:0031410; GO:0032287; GO:0032839; GO:0032991; GO:0040014; GO:0042542; GO:0043025; GO:0043085; GO:0043410; GO:0043524; GO:0045471; GO:0045541; GO:0045859; GO:0046716; GO:0048678; GO:0050665; GO:0051087; GO:0051881; GO:0060047; GO:0060052; GO:0060087; GO:0060088; GO:0072593 16177 XM_044325151.1 0 0 0 45 0 Q86YA3 0 Protein ZGRF1 (GRF-type zinc finger domain-containing protein 1) Homo sapiens (Human) replication fork reversal [GO:0071932] GO:0003723; GO:0004386; GO:0005737; GO:0008270; GO:0016020; GO:0017108; GO:0071932 16178 XM_029342311.2 117 34 29 50 58 Q03357 2.08e-39 Homeobox protein MSH-A Danio rerio (Zebrafish) (Brachydanio rerio) embryonic morphogenesis [GO:0048598]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000977; GO:0000981; GO:0005634; GO:0006357; GO:0048598 16179 XM_044310542.1 10 3 0 6 30 NA NA NA NA NA NA 16180 XM_044327730.1 0 0 41 5 4 NA NA NA NA NA NA 16181 XM_044327962.1 659 386 632 721 964 Q9C0G6 0 Dynein axonemal heavy chain 6 (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0045505; GO:0051959 16182 XR_003822929.2 0 0 0 0 7 NA NA NA NA NA NA 16183 XM_029343571.2 13 15 9 0 11 NA NA NA NA NA NA 16184 XM_044309186.1 737 93 873 20 119 NA NA NA NA NA NA 16185 XM_044316031.1 124 26 55 1 31 NA NA NA NA NA NA 16186 XM_044310915.1 0 0 0 7 0 Q09575 1.07e-37 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 16187 XM_029342167.2 397 153 171 307 308 NA NA NA NA NA NA 16188 XM_044312638.1 0 2 16 1 0 NA NA NA NA NA NA 16189 XM_029347914.2 141 102 79 79 139 Q4L235 0 Beta-alanine-activating enzyme (EC 6.2.1.-) (Acyl-CoA synthetase family member 4) (Protein NRPS998) Homo sapiens (Human) amino acid activation for nonribosomal peptide biosynthetic process [GO:0043041]; beta-alanine metabolic process [GO:0019482]; fatty acid metabolic process [GO:0006631] GO:0005524; GO:0006631; GO:0016878; GO:0019482; GO:0043041 16190 XR_006395677.1 47 51 57 33 58 NA NA NA NA NA NA 16191 XM_044328136.1 150 184 120 354 230 NA NA NA NA NA NA 16192 XM_029345129.2 54 14 0 0 0 NA NA NA NA NA NA 16193 XR_006393189.1 0 0 18 0 42 NA NA NA NA NA NA 16194 XM_044327483.1 213 192 351 876 271 Q7RTR2 4.11e-35 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16195 XM_044327483.1 213 192 351 876 271 Q7RTR2 1.16e-29 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16196 XM_029344411.2 7789 5594 3472 6192 6094 O75746 0 Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial (Araceli hiperlarga) (Aralar) (Aralar1) (Mitochondrial aspartate glutamate carrier 1) (Solute carrier family 25 member 12) Homo sapiens (Human) aspartate family amino acid metabolic process [GO:0009066]; aspartate transmembrane transport [GO:0015810]; gluconeogenesis [GO:0006094]; glutamate biosynthetic process [GO:0006537]; L-glutamate transmembrane transport [GO:0015813]; malate-aspartate shuttle [GO:0043490]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of myelination [GO:0031643]; response to calcium ion [GO:0051592] GO:0000514; GO:0000515; GO:0005313; GO:0005509; GO:0005739; GO:0005743; GO:0006094; GO:0006537; GO:0009066; GO:0010907; GO:0015172; GO:0015183; GO:0015810; GO:0015813; GO:0016020; GO:0022857; GO:0031643; GO:0042802; GO:0043490; GO:0051592; GO:1904024; GO:2001171 16197 XM_029358259.2 1247 1054 765 1312 1376 NA NA NA NA NA NA 16198 XM_029340545.2 267 122 140 293 261 Q5RKZ7 1.78e-177 Molybdenum cofactor biosynthesis protein 1 [Includes: GTP 3',8-cyclase (EC 4.1.99.22) (Molybdenum cofactor biosynthesis protein A); Cyclic pyranopterin monophosphate synthase (EC 4.6.1.17) (Molybdenum cofactor biosynthesis protein C)] Mus musculus (Mouse) Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdopterin cofactor biosynthetic process [GO:0032324] GO:0005525; GO:0005829; GO:0006777; GO:0019008; GO:0032324; GO:0046872; GO:0051539; GO:0061798; GO:0061799 16199 XM_044326709.1 819 440 352 561 514 Q6PDC8 9.06e-70 Major facilitator superfamily domain-containing protein 4A (Major facilitator superfamily domain-containing protein 4) Mus musculus (Mouse) NA GO:0005355; GO:0016020 16200 XM_044326709.1 819 440 352 561 514 Q6PDC8 3.45e-43 Major facilitator superfamily domain-containing protein 4A (Major facilitator superfamily domain-containing protein 4) Mus musculus (Mouse) NA GO:0005355; GO:0016020 16201 XM_029350993.2 287 140 133 205 222 Q9P2G9 3.09e-180 Kelch-like protein 8 Homo sapiens (Human) protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0005654; GO:0006511; GO:0016567; GO:0031463 16202 XM_029350993.2 287 140 133 205 222 Q9P2G9 2.08e-28 Kelch-like protein 8 Homo sapiens (Human) protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0005654; GO:0006511; GO:0016567; GO:0031463 16203 XR_006395968.1 151 50 28 89 101 NA NA NA NA NA NA 16204 XM_029351883.2 38 55 29 50 18 Q5XJY4 1.17e-57 Presenilins-associated rhomboid-like protein, mitochondrial (EC 3.4.21.105) (Mitochondrial intramembrane-cleaving protease PARL) [Cleaved into: P-beta (Pbeta)] Mus musculus (Mouse) membrane protein proteolysis [GO:0033619]; mitochondrial fusion [GO:0008053]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; proteolysis [GO:0006508]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of mitochondrion organization [GO:0010821]; regulation of protein targeting to mitochondrion [GO:1903214]; regulation of proteolysis [GO:0030162]; regulation of reactive oxygen species metabolic process [GO:2000377]; signal peptide processing [GO:0006465] GO:0004175; GO:0004252; GO:0005634; GO:0005739; GO:0005743; GO:0006465; GO:0006508; GO:0008053; GO:0010821; GO:0030162; GO:0033619; GO:0090201; GO:1903146; GO:1903214; GO:2000377; GO:2001243 16205 XM_044322772.1 0 1 32 25 35 Q8IYE1 1.76e-55 Coiled-coil domain-containing protein 13 Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; cytoplasmic microtubule organization [GO:0031122]; non-motile cilium assembly [GO:1905515] GO:0005654; GO:0005813; GO:0005829; GO:0006974; GO:0031122; GO:0034451; GO:0042995; GO:1905515 16206 XM_044322772.1 0 1 32 25 35 Q8IYE1 4.38e-25 Coiled-coil domain-containing protein 13 Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; cytoplasmic microtubule organization [GO:0031122]; non-motile cilium assembly [GO:1905515] GO:0005654; GO:0005813; GO:0005829; GO:0006974; GO:0031122; GO:0034451; GO:0042995; GO:1905515 16207 XM_029352873.2 8 7 6 25 7 NA NA NA NA NA NA 16208 XM_044317713.1 0 0 97 0 0 NA NA NA NA NA NA 16209 XM_029346839.2 279 118 243 244 368 P0C5Y8 0 Alsin (Amyotrophic lateral sclerosis 2 protein homolog) Rattus norvegicus (Rat) axonogenesis [GO:0007409]; behavioral fear response [GO:0001662]; cell death [GO:0008219]; endosomal transport [GO:0016197]; endosome organization [GO:0007032]; in utero embryonic development [GO:0001701]; locomotory behavior [GO:0007626]; lysosomal transport [GO:0007041]; neuromuscular junction development [GO:0007528]; neuron projection morphogenesis [GO:0048812]; positive regulation of GTPase activity [GO:0043547]; positive regulation of protein kinase activity [GO:0045860]; protein homooligomerization [GO:0051260]; protein localization [GO:0008104]; Rac protein signal transduction [GO:0016601]; receptor recycling [GO:0001881]; regulation of endosome size [GO:0051036]; regulation of GTPase activity [GO:0043087]; response to oxidative stress [GO:0006979]; synaptic transmission, glutamatergic [GO:0035249]; vesicle organization [GO:0016050] GO:0001662; GO:0001701; GO:0001726; GO:0001881; GO:0005085; GO:0005096; GO:0005634; GO:0005737; GO:0005769; GO:0005813; GO:0005829; GO:0006979; GO:0007032; GO:0007041; GO:0007409; GO:0007528; GO:0007626; GO:0008104; GO:0008219; GO:0014069; GO:0016020; GO:0016050; GO:0016197; GO:0016601; GO:0030027; GO:0030424; GO:0030425; GO:0030426; GO:0031267; GO:0031982; GO:0032991; GO:0035249; GO:0042802; GO:0042803; GO:0043005; GO:0043025; GO:0043087; GO:0043197; GO:0043231; GO:0043539; GO:0043547; GO:0045202; GO:0045860; GO:0048812; GO:0051036; GO:0051260 16210 XM_029346839.2 279 118 243 244 368 P0C5Y8 1.57e-26 Alsin (Amyotrophic lateral sclerosis 2 protein homolog) Rattus norvegicus (Rat) axonogenesis [GO:0007409]; behavioral fear response [GO:0001662]; cell death [GO:0008219]; endosomal transport [GO:0016197]; endosome organization [GO:0007032]; in utero embryonic development [GO:0001701]; locomotory behavior [GO:0007626]; lysosomal transport [GO:0007041]; neuromuscular junction development [GO:0007528]; neuron projection morphogenesis [GO:0048812]; positive regulation of GTPase activity [GO:0043547]; positive regulation of protein kinase activity [GO:0045860]; protein homooligomerization [GO:0051260]; protein localization [GO:0008104]; Rac protein signal transduction [GO:0016601]; receptor recycling [GO:0001881]; regulation of endosome size [GO:0051036]; regulation of GTPase activity [GO:0043087]; response to oxidative stress [GO:0006979]; synaptic transmission, glutamatergic [GO:0035249]; vesicle organization [GO:0016050] GO:0001662; GO:0001701; GO:0001726; GO:0001881; GO:0005085; GO:0005096; GO:0005634; GO:0005737; GO:0005769; GO:0005813; GO:0005829; GO:0006979; GO:0007032; GO:0007041; GO:0007409; GO:0007528; GO:0007626; GO:0008104; GO:0008219; GO:0014069; GO:0016020; GO:0016050; GO:0016197; GO:0016601; GO:0030027; GO:0030424; GO:0030425; GO:0030426; GO:0031267; GO:0031982; GO:0032991; GO:0035249; GO:0042802; GO:0042803; GO:0043005; GO:0043025; GO:0043087; GO:0043197; GO:0043231; GO:0043539; GO:0043547; GO:0045202; GO:0045860; GO:0048812; GO:0051036; GO:0051260 16211 XM_044322733.1 84 38 146 80 627 NA NA NA NA NA NA 16212 XM_044308183.1 434 250 396 45 0 Q9V9A7 2.69e-163 Probable methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCase subunit beta) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 2) (3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta) Drosophila melanogaster (Fruit fly) coenzyme A metabolic process [GO:0015936]; leucine catabolic process [GO:0006552]; regulation of eclosion [GO:0007563] GO:0004485; GO:0005524; GO:0005739; GO:0005759; GO:0006552; GO:0007563; GO:0015936; GO:1905202 16213 XM_044326993.1 9814 5228 3017 4381 5184 Q99523 3.52e-134 Sortilin (100 kDa NT receptor) (Glycoprotein 95) (Gp95) (Neurotensin receptor 3) (NT3) (NTR3) Homo sapiens (Human) endocytosis [GO:0006897]; endosome to lysosome transport [GO:0008333]; endosome transport via multivesicular body sorting pathway [GO:0032509]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; G protein-coupled receptor signaling pathway [GO:0007186]; glucose import [GO:0046323]; Golgi to endosome transport [GO:0006895]; Golgi to lysosome transport [GO:0090160]; maintenance of synapse structure [GO:0099558]; myotube differentiation [GO:0014902]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of lipoprotein lipase activity [GO:0051005]; neuropeptide signaling pathway [GO:0007218]; neurotrophin TRK receptor signaling pathway [GO:0048011]; ossification [GO:0001503]; plasma membrane to endosome transport [GO:0048227]; post-Golgi vesicle-mediated transport [GO:0006892]; protein targeting to lysosome [GO:0006622]; regulation of gene expression [GO:0010468]; response to insulin [GO:0032868]; vesicle organization [GO:0016050] GO:0001503; GO:0005764; GO:0005765; GO:0005769; GO:0005789; GO:0005794; GO:0005829; GO:0005886; GO:0005905; GO:0006622; GO:0006892; GO:0006895; GO:0006897; GO:0007186; GO:0007218; GO:0008333; GO:0008625; GO:0009986; GO:0010008; GO:0010465; GO:0010468; GO:0014902; GO:0016020; GO:0016050; GO:0019899; GO:0030136; GO:0030140; GO:0030379; GO:0031410; GO:0031965; GO:0032509; GO:0032580; GO:0032868; GO:0045599; GO:0046323; GO:0048011; GO:0048227; GO:0048406; GO:0048471; GO:0051005; GO:0090160; GO:0099558; GO:0150053; GO:1905394 16214 XM_044320234.1 8 14 0 0 5 NA NA NA NA NA NA 16215 XM_029332433.2 329 244 126 203 187 Q6DHL5 2.68e-78 Leucine-rich repeat-containing protein 57 Danio rerio (Zebrafish) (Brachydanio rerio) NA NA 16216 XM_044320630.1 509 19 52 42 11 NA NA NA NA NA NA 16217 XM_029341063.2 2530 2409 1430 1518 897 NA NA NA NA NA NA 16218 XM_029346423.2 1206 885 1090 1196 1703 P17706 5.29e-86 Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP) Homo sapiens (Human) B cell differentiation [GO:0030183]; erythrocyte differentiation [GO:0030218]; glucose homeostasis [GO:0042593]; insulin receptor recycling [GO:0038020]; insulin receptor signaling pathway [GO:0008286]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemotaxis [GO:0050922]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of inflammatory response [GO:0050728]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of interleukin-2-mediated signaling pathway [GO:1902206]; negative regulation of interleukin-4-mediated signaling pathway [GO:1902215]; negative regulation of interleukin-6-mediated signaling pathway [GO:0070104]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage colony-stimulating factor signaling pathway [GO:1902227]; negative regulation of macrophage differentiation [GO:0045650]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of positive thymic T cell selection [GO:1902233]; negative regulation of protein tyrosine kinase activity [GO:0061099]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; negative regulation of type II interferon-mediated signaling pathway [GO:0060336]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; peptidyl-tyrosine dephosphorylation [GO:0035335]; positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902237]; positive regulation of gluconeogenesis [GO:0045722]; positive regulation of PERK-mediated unfolded protein response [GO:1903899]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of type II interferon-mediated signaling pathway [GO:0060334]; T cell differentiation [GO:0030217] GO:0000122; GO:0004725; GO:0004726; GO:0005178; GO:0005634; GO:0005654; GO:0005737; GO:0005783; GO:0005793; GO:0005829; GO:0005886; GO:0008285; GO:0008286; GO:0010804; GO:0010888; GO:0019901; GO:0019905; GO:0030183; GO:0030217; GO:0030218; GO:0030971; GO:0031904; GO:0035335; GO:0038020; GO:0042059; GO:0042532; GO:0042593; GO:0045650; GO:0045722; GO:0046426; GO:0046627; GO:0050728; GO:0050860; GO:0050922; GO:0060334; GO:0060336; GO:0060339; GO:0061099; GO:0070104; GO:0070373; GO:0097677; GO:1902202; GO:1902206; GO:1902215; GO:1902227; GO:1902233; GO:1902237; GO:1903899; GO:2000587 16219 XM_029347174.2 288 269 276 592 392 A8IW99 2.22e-50 Mitochondrial cardiolipin hydrolase (EC 3.1.-.-) (Phospholipase D6 homolog) (PLD 6) Chlamydomonas reinhardtii (Chlamydomonas smithii) lipid catabolic process [GO:0016042]; meiotic cell cycle [GO:0051321] GO:0004519; GO:0005741; GO:0016042; GO:0046872; GO:0051321 16220 XM_029339646.2 2741 2174 1282 2402 2192 Q5ZJK8 0 T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) Gallus gallus (Chicken) protein folding [GO:0006457] GO:0005524; GO:0005832; GO:0006457; GO:0016887; GO:0051082; GO:0140662 16221 XM_029325529.2 5 12 4 1 4 NA NA NA NA NA NA 16222 XM_044307722.1 57 41 162 442 229 O42115 1.69e-28 Aristaless-related homeobox protein (ARX) Danio rerio (Zebrafish) (Brachydanio rerio) enteric nervous system development [GO:0048484]; neuron development [GO:0048666]; pancreatic A cell development [GO:0003322]; regulation of transcription by RNA polymerase II [GO:0006357]; subthalamus development [GO:0021539]; telencephalon development [GO:0021537]; thalamus development [GO:0021794] GO:0000977; GO:0000981; GO:0003322; GO:0005634; GO:0006357; GO:0021537; GO:0021539; GO:0021794; GO:0048484; GO:0048666 16223 XM_044318324.1 24 0 11 0 0 NA NA NA NA NA NA 16224 XM_044327728.1 433 479 255 424 285 Q7ZUZ0 3.5e-53 COP9 signalosome complex subunit 8 (Signalosome subunit 8) Danio rerio (Zebrafish) (Brachydanio rerio) COP9 signalosome assembly [GO:0010387]; protein deneddylation [GO:0000338] GO:0000338; GO:0005737; GO:0008180; GO:0010387 16225 XR_006393004.1 41 2 25 5 151 NA NA NA NA NA NA 16226 XR_006397837.1 551 629 433 527 296 NA NA NA NA NA NA 16227 XR_006392760.1 12 4 20 0 21 NA NA NA NA NA NA 16228 XM_044325884.1 85 41 286 234 135 Q9EPH8 6.62e-170 Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1) Rattus norvegicus (Rat) CRD-mediated mRNA stabilization [GO:0070934]; mRNA processing [GO:0006397]; negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900152]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cytoplasmic translation [GO:2000767]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of viral genome replication [GO:0045070]; RNA splicing [GO:0008380]; RNA-mediated gene silencing [GO:0031047] GO:0000184; GO:0003723; GO:0003729; GO:0003730; GO:0005634; GO:0005737; GO:0005829; GO:0006397; GO:0008022; GO:0008143; GO:0008266; GO:0008380; GO:0010494; GO:0030027; GO:0030425; GO:0031047; GO:0031252; GO:0036464; GO:0045070; GO:0045202; GO:0060213; GO:0070934; GO:0071013; GO:0106002; GO:1900152; GO:1900153; GO:1990124; GO:1990904; GO:2000623; GO:2000767 16229 XM_044325884.1 85 41 286 234 135 Q9EPH8 1.02e-28 Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1) Rattus norvegicus (Rat) CRD-mediated mRNA stabilization [GO:0070934]; mRNA processing [GO:0006397]; negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900152]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cytoplasmic translation [GO:2000767]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of viral genome replication [GO:0045070]; RNA splicing [GO:0008380]; RNA-mediated gene silencing [GO:0031047] GO:0000184; GO:0003723; GO:0003729; GO:0003730; GO:0005634; GO:0005737; GO:0005829; GO:0006397; GO:0008022; GO:0008143; GO:0008266; GO:0008380; GO:0010494; GO:0030027; GO:0030425; GO:0031047; GO:0031252; GO:0036464; GO:0045070; GO:0045202; GO:0060213; GO:0070934; GO:0071013; GO:0106002; GO:1900152; GO:1900153; GO:1990124; GO:1990904; GO:2000623; GO:2000767 16230 XM_044325884.1 85 41 286 234 135 Q9EPH8 5.31e-28 Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1) Rattus norvegicus (Rat) CRD-mediated mRNA stabilization [GO:0070934]; mRNA processing [GO:0006397]; negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900152]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cytoplasmic translation [GO:2000767]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of viral genome replication [GO:0045070]; RNA splicing [GO:0008380]; RNA-mediated gene silencing [GO:0031047] GO:0000184; GO:0003723; GO:0003729; GO:0003730; GO:0005634; GO:0005737; GO:0005829; GO:0006397; GO:0008022; GO:0008143; GO:0008266; GO:0008380; GO:0010494; GO:0030027; GO:0030425; GO:0031047; GO:0031252; GO:0036464; GO:0045070; GO:0045202; GO:0060213; GO:0070934; GO:0071013; GO:0106002; GO:1900152; GO:1900153; GO:1990124; GO:1990904; GO:2000623; GO:2000767 16231 XM_044311739.1 16 0 2 0 1 NA NA NA NA NA NA 16232 XM_029344309.2 3 0 15 3 0 Q7Z020 4.05e-129 Transient receptor potential cation channel subfamily A member 1 (dTRPA1) (Ankyrin-like with transmembrane domains protein 1) (dANKTM1) Drosophila melanogaster (Fruit fly) calcium ion transport [GO:0006816]; cation transport [GO:0006812]; cellular response to heat [GO:0034605]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; detection of temperature stimulus involved in thermoception [GO:0050960]; mechanosensory behavior [GO:0007638]; negative phototaxis [GO:0046957]; neuronal signal transduction [GO:0023041]; phototransduction [GO:0007602]; positive regulation of calcium-mediated signaling [GO:0050850]; response to heat [GO:0009408]; response to light stimulus [GO:0009416]; temperature compensation of the circadian clock [GO:0010378]; thermosensory behavior [GO:0040040]; thermotaxis [GO:0043052] GO:0001580; GO:0005261; GO:0005262; GO:0005886; GO:0006812; GO:0006816; GO:0007602; GO:0007638; GO:0009408; GO:0009416; GO:0010378; GO:0015276; GO:0016020; GO:0023041; GO:0034605; GO:0034703; GO:0040040; GO:0043052; GO:0046957; GO:0050850; GO:0050960; GO:0050965; GO:0050968; GO:0097604 16233 XM_044308492.1 43 35 75 162 34 O93403 2e-23 Carbohydrate sulfotransferase 3 (EC 2.8.2.17) (EC 2.8.2.21) (Chondroitin 6-O-sulfotransferase 1) (C6ST-1) (Nervous system involved sulfotransferase) Tetronarce californica (Pacific electric ray) (Torpedo californica) carbohydrate metabolic process [GO:0005975]; chondroitin sulfate biosynthetic process [GO:0030206] GO:0000139; GO:0005975; GO:0008459; GO:0030206 16234 XM_044319108.1 236 148 85 402 180 NA NA NA NA NA NA 16235 XM_029331197.2 45 6 40 75 22 Q805E5 1.01e-34 Carbohydrate sulfotransferase 14 (EC 2.8.2.-) (Dermatan 4-sulfotransferase 1) (D4ST-1) (zD4ST-1) Danio rerio (Zebrafish) (Brachydanio rerio) carbohydrate biosynthetic process [GO:0016051]; dermatan sulfate proteoglycan metabolic process [GO:0050655] GO:0000139; GO:0001537; GO:0008146; GO:0016051; GO:0050655 16236 XM_044316772.1 97 2 17 7 38 NA NA NA NA NA NA 16237 XM_029340687.2 101 96 72 120 222 Q9UNP9 7.64e-156 Peptidyl-prolyl cis-trans isomerase E (PPIase E) (EC 5.2.1.8) (Cyclophilin E) (Cyclophilin-33) (Rotamase E) Homo sapiens (Human) mRNA splicing, via spliceosome [GO:0000398]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; regulation of DNA-templated transcription [GO:0006355] GO:0000398; GO:0000413; GO:0003723; GO:0003729; GO:0003755; GO:0005576; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006355; GO:0006457; GO:0008143; GO:0016018; GO:0016607; GO:0034774; GO:0045070; GO:0071007; GO:0071013; GO:1904813 16238 XM_044319710.1 148 0 0 997 0 Q54H46 1.89e-24 Probable serine/threonine-protein kinase drkA (EC 2.7.11.1) (Receptor-like kinase 1) (Receptor-like kinase A) (Vesicle-associated receptor tyrosine kinase-like protein 1) Dictyostelium discoideum (Social amoeba) receptor signaling pathway via STAT [GO:0097696]; signal transduction [GO:0007165] GO:0004672; GO:0004674; GO:0004713; GO:0005524; GO:0005737; GO:0007165; GO:0016020; GO:0097677; GO:0097696; GO:0106310 16239 XR_006391479.1 394 274 193 402 462 NA NA NA NA NA NA 16240 XM_044310239.1 18 15 2 27 162 O60290 1.99e-67 Zinc finger protein 862 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006355; GO:0046872; GO:0046983 16241 XR_006395458.1 724 791 431 440 427 NA NA NA NA NA NA 16242 XM_029350674.2 369 197 498 477 566 P54288 9.93e-125 Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2) Oryctolagus cuniculus (Rabbit) calcium ion import [GO:0070509]; chemical synaptic transmission [GO:0007268]; membrane depolarization during atrial cardiac muscle cell action potential [GO:0098912]; positive regulation of calcium ion transport [GO:0051928]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ion transmembrane transport [GO:0034765]; visual perception [GO:0007601] GO:0007268; GO:0007601; GO:0008331; GO:0034765; GO:0051015; GO:0051928; GO:0070509; GO:0086056; GO:0086091; GO:0098684; GO:0098793; GO:0098912; GO:0099626; GO:1990454 16243 XM_044325153.1 112 101 62 46 34 P70085 6.35e-96 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Oryzias latipes (Japanese rice fish) (Japanese killifish) hormone biosynthetic process [GO:0042446]; progesterone metabolic process [GO:0042448]; steroid biosynthetic process [GO:0006694] GO:0004508; GO:0005506; GO:0006694; GO:0016020; GO:0020037; GO:0042446; GO:0042448; GO:0047442 16244 XM_044317040.1 0 0 53 177 342 Q6GQB5 3.28e-32 Akirin-2 (XAkirin2) Xenopus laevis (African clawed frog) neurogenesis [GO:0022008]; protein transport [GO:0015031] GO:0005634; GO:0015031; GO:0022008; GO:0030674 16245 XM_029355041.2 1668 2057 1475 1625 1772 B5X4E0 2.83e-72 Calumenin-B Salmo salar (Atlantic salmon) NA GO:0005509; GO:0005576; GO:0005789; GO:0005794; GO:0033018; GO:0042470 16246 XR_003823037.2 49 33 20 77 70 NA NA NA NA NA NA 16247 XM_044316081.1 0 0 67 0 0 O60290 1.38e-67 Zinc finger protein 862 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006355; GO:0046872; GO:0046983 16248 XM_029339550.2 909 948 677 999 581 NA NA NA NA NA NA 16249 XM_029349633.2 33 75 1 0 1 NA NA NA NA NA NA 16250 XM_029358598.2 8 5 0 7 3 Q5R6P5 4.42e-33 Mediator of RNA polymerase II transcription subunit 10 (Mediator complex subunit 10) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) regulation of transcription by RNA polymerase II [GO:0006357] GO:0003712; GO:0005654; GO:0006357; GO:0016592; GO:0070847 16251 XM_044325331.1 499 361 447 343 593 Q9HAR2 1.14e-55 Adhesion G protein-coupled receptor L3 (Calcium-independent alpha-latrotoxin receptor 3) (CIRL-3) (Latrophilin-3) (Lectomedin-3) Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; brain development [GO:0007420]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; G protein-coupled receptor signaling pathway [GO:0007186]; neuron migration [GO:0001764]; synapse assembly [GO:0007416] GO:0001764; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007166; GO:0007186; GO:0007189; GO:0007416; GO:0007420; GO:0016020; GO:0030246; GO:0030424; GO:0098742; GO:0098978 16252 XR_006393702.1 160 74 82 137 179 NA NA NA NA NA NA 16253 XM_029333709.2 165 84 57 113 81 Q3TUU5 4.69e-47 Testis-expressed protein 30 Mus musculus (Mouse) NA NA 16254 XM_044327223.1 1023 576 624 1064 1152 Q9NRC6 0 Spectrin beta chain, non-erythrocytic 5 (Beta-V spectrin) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; actin filament capping [GO:0051693]; Golgi organization [GO:0007030]; lysosomal transport [GO:0007041] GO:0002046; GO:0003779; GO:0005737; GO:0005829; GO:0005875; GO:0007030; GO:0007041; GO:0008022; GO:0008091; GO:0016020; GO:0019894; GO:0030036; GO:0030507; GO:0032029; GO:0032391; GO:0034452; GO:0042802; GO:0043621; GO:0045179; GO:0045505; GO:0051015; GO:0051693; GO:0097381 16255 XM_044327223.1 1023 576 624 1064 1152 Q9NRC6 9.01e-118 Spectrin beta chain, non-erythrocytic 5 (Beta-V spectrin) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; actin filament capping [GO:0051693]; Golgi organization [GO:0007030]; lysosomal transport [GO:0007041] GO:0002046; GO:0003779; GO:0005737; GO:0005829; GO:0005875; GO:0007030; GO:0007041; GO:0008022; GO:0008091; GO:0016020; GO:0019894; GO:0030036; GO:0030507; GO:0032029; GO:0032391; GO:0034452; GO:0042802; GO:0043621; GO:0045179; GO:0045505; GO:0051015; GO:0051693; GO:0097381 16256 XM_044327223.1 1023 576 624 1064 1152 Q9NRC6 6.23e-99 Spectrin beta chain, non-erythrocytic 5 (Beta-V spectrin) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; actin filament capping [GO:0051693]; Golgi organization [GO:0007030]; lysosomal transport [GO:0007041] GO:0002046; GO:0003779; GO:0005737; GO:0005829; GO:0005875; GO:0007030; GO:0007041; GO:0008022; GO:0008091; GO:0016020; GO:0019894; GO:0030036; GO:0030507; GO:0032029; GO:0032391; GO:0034452; GO:0042802; GO:0043621; GO:0045179; GO:0045505; GO:0051015; GO:0051693; GO:0097381 16257 XM_044327223.1 1023 576 624 1064 1152 Q9NRC6 2.97e-28 Spectrin beta chain, non-erythrocytic 5 (Beta-V spectrin) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; actin filament capping [GO:0051693]; Golgi organization [GO:0007030]; lysosomal transport [GO:0007041] GO:0002046; GO:0003779; GO:0005737; GO:0005829; GO:0005875; GO:0007030; GO:0007041; GO:0008022; GO:0008091; GO:0016020; GO:0019894; GO:0030036; GO:0030507; GO:0032029; GO:0032391; GO:0034452; GO:0042802; GO:0043621; GO:0045179; GO:0045505; GO:0051015; GO:0051693; GO:0097381 16258 XM_029341991.2 0 0 0 76 153 Q5TYP4 1.07e-103 Uncharacterized protein C1orf112 homolog Danio rerio (Zebrafish) (Brachydanio rerio) NA NA 16259 XM_029332381.2 79 18 61 36 108 P78357 1.14e-59 Contactin-associated protein 1 (Caspr) (Caspr1) (Neurexin IV) (Neurexin-4) (p190) Homo sapiens (Human) axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cytoskeleton organization [GO:0007010]; mitochondrion organization [GO:0007005]; myelination in peripheral nervous system [GO:0022011]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; neuron projection morphogenesis [GO:0048812]; neuronal action potential propagation [GO:0019227]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; postsynaptic density organization [GO:0097106]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; regulation of synapse maturation [GO:0090128]; signal transduction [GO:0007165] GO:0002175; GO:0005886; GO:0007005; GO:0007010; GO:0007155; GO:0007165; GO:0007409; GO:0016020; GO:0017124; GO:0019227; GO:0022010; GO:0022011; GO:0030913; GO:0033010; GO:0033270; GO:0038023; GO:0048786; GO:0048812; GO:0050884; GO:0050885; GO:0071205; GO:0090128; GO:0097106; GO:0098529; GO:0098978; GO:1990227 16260 XM_044308170.1 4212 3293 2635 4763 4640 P95329 1.13e-178 Malate synthase (EC 2.3.3.9) Myxococcus xanthus (strain DK1622) glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099] GO:0004474; GO:0005737; GO:0006097; GO:0006099 16261 XM_029343396.2 3847 7090 2531 4996 5450 Q503V9 1.65e-84 Uridylate-specific endoribonuclease B (EC 4.6.1.-) (Protein endoU-B) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0003723; GO:0004521; GO:0016829; GO:0046872 16262 XM_044312908.1 18 28 11 42 26 NA NA NA NA NA NA 16263 XM_044319206.1 49 0 35 0 31 NA NA NA NA NA NA 16264 XM_029330077.2 435 385 191 633 138 NA NA NA NA NA NA 16265 XM_044309354.1 88 131 70 38 146 NA NA NA NA NA NA 16266 XM_044319750.1 141 433 127 269 356 Q54VV7 4.29e-24 Probable serine/threonine-protein kinase DDB_G0280111 (EC 2.7.11.1) Dictyostelium discoideum (Social amoeba) protein phosphorylation [GO:0006468] GO:0004674; GO:0005524; GO:0005543; GO:0005737; GO:0006468; GO:0106310 16267 XM_044329338.1 99 69 159 281 259 P58027 3.9e-111 Amine oxidase [flavin-containing] A (EC 1.4.3.21) (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A) Canis lupus familiaris (Dog) (Canis familiaris) catecholamine metabolic process [GO:0006584]; neurotransmitter catabolic process [GO:0042135] GO:0005739; GO:0005741; GO:0006584; GO:0008131; GO:0042135; GO:0050660; GO:0052595; GO:0052596; GO:0097621 16268 XM_044329338.1 99 69 159 281 259 P58027 3.9e-111 Amine oxidase [flavin-containing] A (EC 1.4.3.21) (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A) Canis lupus familiaris (Dog) (Canis familiaris) catecholamine metabolic process [GO:0006584]; neurotransmitter catabolic process [GO:0042135] GO:0005739; GO:0005741; GO:0006584; GO:0008131; GO:0042135; GO:0050660; GO:0052595; GO:0052596; GO:0097621 16269 XM_029338892.2 56 0 122 0 229 Q5RAS8 8.76e-30 Transmembrane protein 199 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cellular iron ion homeostasis [GO:0006879]; cellular response to increased oxygen levels [GO:0036295]; lysosomal lumen acidification [GO:0007042]; lysosomal protein catabolic process [GO:1905146]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072] GO:0005764; GO:0005783; GO:0005789; GO:0006879; GO:0007042; GO:0016471; GO:0030663; GO:0033116; GO:0036295; GO:0070072; GO:1905146 16270 XM_044322567.1 221 367 8 311 0 Q5BK60 1.89e-26 Kelch-like protein 38 Rattus norvegicus (Rat) NA NA 16271 XM_029349797.2 509 546 791 1038 383 NA NA NA NA NA NA 16272 XM_044323413.1 18 0 0 0 0 NA NA NA NA NA NA 16273 XM_029335104.2 0 29 0 0 83 NA NA NA NA NA NA 16274 XM_029339867.2 6067 5363 2813 4826 3034 Q5RBM1 1.19e-133 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit) (Ribophorin II) (RPN-II) (Ribophorin-2) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) protein N-linked glycosylation [GO:0006487] GO:0006487; GO:0008250 16275 XM_044317808.1 1172 1324 255 808 573 Q5U4U5 9.12e-35 Mitochondrial import inner membrane translocase subunit Tim22 Xenopus laevis (African clawed frog) protein insertion into mitochondrial inner membrane [GO:0045039] GO:0042721; GO:0045039 16276 XR_006392396.1 125 31 52 65 82 NA NA NA NA NA NA 16277 XM_029331509.2 388 652 354 729 491 NA NA NA NA NA NA 16278 XM_044307311.1 12 64 0 99 35 NA NA NA NA NA NA 16279 XM_029353190.2 5832 5150 3951 8936 10481 Q5TCZ1 3.2e-48 SH3 and PX domain-containing protein 2A (Adapter protein TKS5) (Five SH3 domain-containing protein) (SH3 multiple domains protein 1) (Tyrosine kinase substrate with five SH3 domains) Homo sapiens (Human) in utero embryonic development [GO:0001701]; osteoclast fusion [GO:0072675]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801] GO:0001701; GO:0002020; GO:0002102; GO:0005546; GO:0005737; GO:0005829; GO:0006801; GO:0010314; GO:0016176; GO:0032266; GO:0042554; GO:0042995; GO:0043325; GO:0070161; GO:0070273; GO:0072675 16280 XM_029353931.2 86 68 27 30 125 D3Z5L6 4.34e-64 MFS-type transporter SLC18B1 (Solute carrier family 18 member B1) (Vesicular polyamine transporter) (VPAT) Mus musculus (Mouse) serotonin transport [GO:0006837]; serotonin uptake [GO:0051610]; spermidine transport [GO:0015848]; spermine transport [GO:0000296] GO:0000296; GO:0006837; GO:0015311; GO:0015312; GO:0015848; GO:0022857; GO:0030667; GO:0030672; GO:0051610 16281 XM_029356714.2 10762 9121 5983 9409 8652 Q6QEF8 8.5e-143 Coronin-6 (Coronin-like protein E) (Clipin-E) Homo sapiens (Human) actin filament organization [GO:0007015]; cell migration [GO:0016477] GO:0007015; GO:0016477; GO:0051015 16282 XM_029358540.2 73 48 34 51 110 Q55DL2 1.75e-48 Histidine protein methyltransferase 1 homolog (EC 2.1.1.85) (Protein METTL18 homolog) Dictyostelium discoideum (Social amoeba) peptidyl-histidine methylation, to form tele-methylhistidine [GO:0042038]; peptidyl-lysine monomethylation [GO:0018026] GO:0005730; GO:0005829; GO:0018026; GO:0018064; GO:0042038 16283 XM_044317241.1 49 26 25 51 245 NA NA NA NA NA NA 16284 XM_044326204.1 59 41 67 115 191 NA NA NA NA NA NA 16285 XM_029333648.1 362 142 237 353 371 Q6PAY8 8.88e-141 Hydroxysteroid dehydrogenase-like protein 2 (EC 1.-.-.-) Xenopus laevis (African clawed frog) NA GO:0005777; GO:0016491 16286 XM_029336356.2 384 249 313 281 98 Q9CR48 1.56e-35 DNA damage-regulated autophagy modulator protein 2 (Transmembrane protein 77) Mus musculus (Mouse) apoptotic process [GO:0006915]; autophagy [GO:0006914]; photoreceptor cell maintenance [GO:0045494]; regulation of autophagy [GO:0010506]; visual perception [GO:0007601] GO:0001917; GO:0005737; GO:0005764; GO:0005765; GO:0005794; GO:0006914; GO:0006915; GO:0007601; GO:0010506; GO:0016324; GO:0043231; GO:0045494 16287 XM_029349408.2 0 40 29 6 0 NA NA NA NA NA NA 16288 XM_029350257.2 46 0 0 0 0 NA NA NA NA NA NA 16289 XM_029335704.2 94 68 92 58 99 Q4R7T7 1.37e-175 Tubulin delta chain (Delta-tubulin) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) cell projection organization [GO:0030030]; microtubule-based process [GO:0007017]; positive regulation of smoothened signaling pathway [GO:0045880] GO:0005200; GO:0005525; GO:0005634; GO:0005737; GO:0005814; GO:0005874; GO:0005929; GO:0007017; GO:0030030; GO:0045880 16290 XM_044307632.1 13 0 8 7 101 Q0V8S9 5.75e-22 Contactin-associated protein-like 5 (Cell recognition molecule Caspr5) Gallus gallus (Chicken) cell adhesion [GO:0007155] GO:0007155; GO:0016020 16291 XM_044308540.1 0 10 0 2 0 Q9DBN1 9.24e-29 Stimulated by retinoic acid gene 6 protein-like (STRA6-like protein) (Retinol-binding protein 4 receptor 2) (RBP4 receptor 2) Mus musculus (Mouse) establishment of localization in cell [GO:0051649]; retinol transport [GO:0034633]; vitamin A import into cell [GO:0071939] GO:0005886; GO:0034633; GO:0051649; GO:0071939 16292 XM_029358434.2 0 29 0 20 0 Q708S6 8.77e-41 Acid-sensing ion channel 1C (ASIC1-C) (Acid-sensing ion channel 1.3-C) (Amiloride-sensitive cation channel 2-C, neuronal-C) (ZASIC1.3) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to pH [GO:0071467]; protein homotrimerization [GO:0070207]; sodium ion transmembrane transport [GO:0035725] GO:0005261; GO:0005886; GO:0015280; GO:0035725; GO:0044736; GO:0070207; GO:0071467 16293 XM_029341800.2 3125 2107 1568 2554 2486 Q04721 0 Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation (N2ECD); Notch 2 intracellular domain (N2ICD)] Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; atrial septum morphogenesis [GO:0060413]; atrioventricular node development [GO:0003162]; axon guidance [GO:0007411]; BMP signaling pathway [GO:0030509]; bone remodeling [GO:0046849]; cell fate determination [GO:0001709]; cellular response to tumor cell [GO:0071228]; cholangiocyte proliferation [GO:1990705]; ciliary body morphogenesis [GO:0061073]; defense response to bacterium [GO:0042742]; embryonic limb morphogenesis [GO:0030326]; glomerular capillary formation [GO:0072104]; heart looping [GO:0001947]; hemopoiesis [GO:0030097]; hepatocyte proliferation [GO:0072574]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; intrahepatic bile duct development [GO:0035622]; left/right axis specification [GO:0070986]; marginal zone B cell differentiation [GO:0002315]; morphogenesis of an epithelial sheet [GO:0002011]; multicellular organism growth [GO:0035264]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; placenta blood vessel development [GO:0060674]; podocyte development [GO:0072015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of Ras protein signal transduction [GO:0046579]; proximal tubule development [GO:0072014]; pulmonary valve morphogenesis [GO:0003184]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of osteoclast development [GO:2001204]; wound healing [GO:0042060] GO:0000122; GO:0000139; GO:0001701; GO:0001709; GO:0001947; GO:0002011; GO:0002315; GO:0002437; GO:0003162; GO:0003184; GO:0005509; GO:0005576; GO:0005634; GO:0005654; GO:0005789; GO:0005886; GO:0005929; GO:0006915; GO:0006959; GO:0007219; GO:0007399; GO:0007411; GO:0009887; GO:0009986; GO:0010629; GO:0010838; GO:0016020; GO:0019899; GO:0030097; GO:0030326; GO:0030509; GO:0030513; GO:0035264; GO:0035622; GO:0038023; GO:0042060; GO:0042742; GO:0043011; GO:0043065; GO:0043066; GO:0043235; GO:0045672; GO:0046579; GO:0046849; GO:0051059; GO:0060413; GO:0060674; GO:0061073; GO:0061314; GO:0070374; GO:0070986; GO:0071228; GO:0072014; GO:0072015; GO:0072104; GO:0072574; GO:1990705; GO:2000249; GO:2001204 16294 XM_029341800.2 3125 2107 1568 2554 2486 Q04721 0 Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation (N2ECD); Notch 2 intracellular domain (N2ICD)] Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; atrial septum morphogenesis [GO:0060413]; atrioventricular node development [GO:0003162]; axon guidance [GO:0007411]; BMP signaling pathway [GO:0030509]; bone remodeling [GO:0046849]; cell fate determination [GO:0001709]; cellular response to tumor cell [GO:0071228]; cholangiocyte proliferation [GO:1990705]; ciliary body morphogenesis [GO:0061073]; defense response to bacterium [GO:0042742]; embryonic limb morphogenesis [GO:0030326]; glomerular capillary formation [GO:0072104]; heart looping [GO:0001947]; hemopoiesis [GO:0030097]; hepatocyte proliferation [GO:0072574]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; intrahepatic bile duct development [GO:0035622]; left/right axis specification [GO:0070986]; marginal zone B cell differentiation [GO:0002315]; morphogenesis of an epithelial sheet [GO:0002011]; multicellular organism growth [GO:0035264]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; placenta blood vessel development [GO:0060674]; podocyte development [GO:0072015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of Ras protein signal transduction [GO:0046579]; proximal tubule development [GO:0072014]; pulmonary valve morphogenesis [GO:0003184]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of osteoclast development [GO:2001204]; wound healing [GO:0042060] GO:0000122; GO:0000139; GO:0001701; GO:0001709; GO:0001947; GO:0002011; GO:0002315; GO:0002437; GO:0003162; GO:0003184; GO:0005509; GO:0005576; GO:0005634; GO:0005654; GO:0005789; GO:0005886; GO:0005929; GO:0006915; GO:0006959; GO:0007219; GO:0007399; GO:0007411; GO:0009887; GO:0009986; GO:0010629; GO:0010838; GO:0016020; GO:0019899; GO:0030097; GO:0030326; GO:0030509; GO:0030513; GO:0035264; GO:0035622; GO:0038023; GO:0042060; GO:0042742; GO:0043011; GO:0043065; GO:0043066; GO:0043235; GO:0045672; GO:0046579; GO:0046849; GO:0051059; GO:0060413; GO:0060674; GO:0061073; GO:0061314; GO:0070374; GO:0070986; GO:0071228; GO:0072014; GO:0072015; GO:0072104; GO:0072574; GO:1990705; GO:2000249; GO:2001204 16295 XM_029341800.2 3125 2107 1568 2554 2486 Q04721 0 Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation (N2ECD); Notch 2 intracellular domain (N2ICD)] Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; atrial septum morphogenesis [GO:0060413]; atrioventricular node development [GO:0003162]; axon guidance [GO:0007411]; BMP signaling pathway [GO:0030509]; bone remodeling [GO:0046849]; cell fate determination [GO:0001709]; cellular response to tumor cell [GO:0071228]; cholangiocyte proliferation [GO:1990705]; ciliary body morphogenesis [GO:0061073]; defense response to bacterium [GO:0042742]; embryonic limb morphogenesis [GO:0030326]; glomerular capillary formation [GO:0072104]; heart looping [GO:0001947]; hemopoiesis [GO:0030097]; hepatocyte proliferation [GO:0072574]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; intrahepatic bile duct development [GO:0035622]; left/right axis specification [GO:0070986]; marginal zone B cell differentiation [GO:0002315]; morphogenesis of an epithelial sheet [GO:0002011]; multicellular organism growth [GO:0035264]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; placenta blood vessel development [GO:0060674]; podocyte development [GO:0072015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of Ras protein signal transduction [GO:0046579]; proximal tubule development [GO:0072014]; pulmonary valve morphogenesis [GO:0003184]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of osteoclast development [GO:2001204]; wound healing [GO:0042060] GO:0000122; GO:0000139; GO:0001701; GO:0001709; GO:0001947; GO:0002011; GO:0002315; GO:0002437; GO:0003162; GO:0003184; GO:0005509; GO:0005576; GO:0005634; GO:0005654; GO:0005789; GO:0005886; GO:0005929; GO:0006915; GO:0006959; GO:0007219; GO:0007399; GO:0007411; GO:0009887; GO:0009986; GO:0010629; GO:0010838; GO:0016020; GO:0019899; GO:0030097; GO:0030326; GO:0030509; GO:0030513; GO:0035264; GO:0035622; GO:0038023; GO:0042060; GO:0042742; GO:0043011; GO:0043065; GO:0043066; GO:0043235; GO:0045672; GO:0046579; GO:0046849; GO:0051059; GO:0060413; GO:0060674; GO:0061073; GO:0061314; GO:0070374; GO:0070986; GO:0071228; GO:0072014; GO:0072015; GO:0072104; GO:0072574; GO:1990705; GO:2000249; GO:2001204 16296 XM_044309566.1 532 537 415 688 717 NA NA NA NA NA NA 16297 XM_044322422.1 0 0 21 65 0 Q8R512 5e-80 UBX domain-containing protein 11 (Socius) (UBX domain-containing protein 5) Rattus norvegicus (Rat) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] GO:0005737; GO:0005856; GO:0043130; GO:0043161 16298 XM_044311507.1 1 0 0 6 0 NA NA NA NA NA NA 16299 XM_029337525.2 293 259 134 327 341 P9WM79 2.86e-79 Probable polyglutamine synthesis accessory protein Rv0574c Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) NA NA 16300 XM_029348124.2 9 71 218 0 943 NA NA NA NA NA NA 16301 XM_029333342.2 997 678 127 1142 1079 Q8WVS4 7.12e-115 Cytoplasmic dynein 2 intermediate chain 1 (Dynein 2 intermediate chain 1) (WD repeat-containing protein 60) Homo sapiens (Human) cilium assembly [GO:0060271]; embryonic skeletal system morphogenesis [GO:0048704]; intraciliary retrograde transport [GO:0035721]; intraciliary transport [GO:0042073]; microtubule-based movement [GO:0007018] GO:0000242; GO:0005615; GO:0005813; GO:0005868; GO:0005929; GO:0007018; GO:0035721; GO:0042073; GO:0045503; GO:0045504; GO:0048704; GO:0060271; GO:0097014; GO:0097542; GO:0097546 16302 XM_029354906.2 367 83 90 189 152 Q7ZWN0 5.53e-175 Lipase maturation factor 2 Xenopus laevis (African clawed frog) protein maturation [GO:0051604] GO:0005789; GO:0051604 16303 XM_044315324.1 26 36 19 9 1 NA NA NA NA NA NA 16304 XM_029358395.2 21 0 2 0 1 NA NA NA NA NA NA 16305 XR_006391859.1 0 4 0 19 6 NA NA NA NA NA NA 16306 XM_029357347.2 41 0 26 66 12 NA NA NA NA NA NA 16307 XM_029356795.2 155 213 119 72 272 Q6P3S6 7.88e-79 F-box only protein 42 (Just one F-box and Kelch domain-containing protein) Homo sapiens (Human) NA GO:0019005; GO:1990756 16308 XM_044308610.1 487 405 278 441 431 Q641A1 1.36e-64 Poly(A) RNA polymerase GLD2-A (EC 2.7.7.19) (PAP-associated domain-containing protein 4-A) Xenopus laevis (African clawed frog) mRNA processing [GO:0006397]; negative regulation of miRNA catabolic process [GO:2000626]; oogenesis [GO:0048477]; RNA polyadenylation [GO:0043631]; RNA stabilization [GO:0043489] GO:0004652; GO:0005524; GO:0005737; GO:0006397; GO:0034062; GO:0043489; GO:0043631; GO:0046872; GO:0048477; GO:0070566; GO:2000626 16309 XM_044310154.1 29 41 61 25 26 NA NA NA NA NA NA 16310 XM_029346245.2 192 34 38 160 189 NA NA NA NA NA NA 16311 XM_029344632.2 5548 2793 1097 4297 1209 NA NA NA NA NA NA 16312 XM_044307695.1 71 60 48 119 43 Q9MYM7 3.7e-29 Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.86) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1) Pongo pygmaeus (Bornean orangutan) lipid metabolic process [GO:0006629]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0006629; GO:0047275 16313 XM_029332637.2 105528 63486 55581 56934 19097 P26632 1.1e-51 Early growth response protein 1 (EGR-1) (Zinc finger protein Krox-24) Danio rerio (Zebrafish) (Brachydanio rerio) camera-type eye development [GO:0043010]; circadian regulation of gene expression [GO:0032922]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; embryonic viscerocranium morphogenesis [GO:0048703]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005737; GO:0006357; GO:0008270; GO:0010385; GO:0032922; GO:0043010; GO:0043565; GO:0044729; GO:0045893; GO:0045944; GO:0048703; GO:0060059; GO:1990841 16314 XM_044308469.1 214 389 249 206 344 Q4R3J0 7.11e-65 RNA 3'-terminal phosphate cyclase (RNA cyclase) (RNA-3'-phosphate cyclase) (EC 6.5.1.4) (RNA terminal phosphate cyclase domain-containing protein 1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) RNA processing [GO:0006396] GO:0003963; GO:0005524; GO:0005654; GO:0006396 16315 XR_006393950.1 47 42 13 11 19 NA NA NA NA NA NA 16316 XM_044309181.1 10 30 13 26 13 NA NA NA NA NA NA 16317 XM_044314173.1 191 134 145 12 121 Q91287 2.64e-76 Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (PFR3) Pleurodeles waltl (Iberian ribbed newt) apoptotic process [GO:0006915]; positive regulation of cell population proliferation [GO:0008284] GO:0005007; GO:0005524; GO:0005886; GO:0006915; GO:0008284 16318 XM_044314173.1 191 134 145 12 121 Q91287 7.99e-38 Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (PFR3) Pleurodeles waltl (Iberian ribbed newt) apoptotic process [GO:0006915]; positive regulation of cell population proliferation [GO:0008284] GO:0005007; GO:0005524; GO:0005886; GO:0006915; GO:0008284 16319 XM_029333334.2 118 0 0 298 253 Q6UW02 9.03e-79 Cytochrome P450 20A1 (EC 1.14.-.-) Homo sapiens (Human) NA GO:0004497; GO:0005506; GO:0016020; GO:0016705; GO:0020037 16320 XM_044313511.1 0 3 53 5 27 A0A0C2SRU0 4.52e-80 Decarboxylase iboD (EC 4.1.1.-) (Ibotenic acid biosynthesis cluster protein D) Amanita muscaria (strain Koide BX008) phospholipid biosynthetic process [GO:0008654] GO:0004609; GO:0008654 16321 XR_003827324.2 11 2 0 6 0 NA NA NA NA NA NA 16322 XM_044311461.1 10 0 13 0 0 D3ZS74 8.72e-69 Metalloendopeptidase OMA1, mitochondrial (EC 3.4.24.-) (Overlapping with the m-AAA protease 1 homolog) Rattus norvegicus (Rat) cristae formation [GO:0042407]; diet induced thermogenesis [GO:0002024]; energy homeostasis [GO:0097009]; glucose metabolic process [GO:0006006]; HRI-mediated signaling [GO:0140468]; integrated stress response signaling [GO:0140467]; lipid metabolic process [GO:0006629]; mitochondrial protein processing [GO:0034982]; mitochondrial respiratory chain complex assembly [GO:0033108]; mitochondrion organization [GO:0007005]; negative regulation of mitochondrial fusion [GO:0010637]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cold-induced thermogenesis [GO:0120162]; protein autoprocessing [GO:0016540]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of cristae formation [GO:1903850]; zymogen activation [GO:0031638] GO:0002024; GO:0004222; GO:0005739; GO:0005743; GO:0006006; GO:0006515; GO:0006629; GO:0007005; GO:0008289; GO:0010637; GO:0016020; GO:0016540; GO:0031638; GO:0031966; GO:0033108; GO:0034982; GO:0042407; GO:0043065; GO:0046872; GO:0051603; GO:0097009; GO:0120162; GO:0140467; GO:0140468; GO:1903850 16323 XM_044319469.1 465 413 323 306 577 Q2KHY5 2.18e-21 Fanconi anemia core complex-associated protein 24 (Fanconi anemia-associated protein of 24 kDa) Bos taurus (Bovine) interstrand cross-link repair [GO:0036297] GO:0000785; GO:0003677; GO:0003682; GO:0005654; GO:0036297; GO:0043240; GO:0071821 16324 XM_029357907.2 616 117 64 69 28 NA NA NA NA NA NA 16325 XM_044310295.1 1310 1680 1183 1483 1073 Q17CS8 4.18e-128 Kynurenine aminotransferase (EC 2.6.1.-) (EC 2.6.1.63) (EC 2.6.1.7) (AeKAT) Aedes aegypti (Yellowfever mosquito) (Culex aegypti) biosynthetic process [GO:0009058]; L-kynurenine catabolic process [GO:0097053] GO:0005739; GO:0009058; GO:0016212; GO:0030170; GO:0047315; GO:0097053 16326 XM_044322575.1 98 115 192 0 0 Q7RTR2 4.39e-62 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16327 XM_044322575.1 98 115 192 0 0 Q7RTR2 2.07e-59 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16328 XM_044322575.1 98 115 192 0 0 Q7RTR2 3.86e-56 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16329 XM_044322575.1 98 115 192 0 0 Q7RTR2 2.92e-38 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16330 XM_044317007.1 519 276 161 314 222 Q8C206 3e-32 G-protein coupled receptor 157 Mus musculus (Mouse) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; circadian behavior [GO:0048512]; G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; radial glial cell differentiation [GO:0060019] GO:0004930; GO:0005886; GO:0007166; GO:0007186; GO:0007189; GO:0048512; GO:0051482; GO:0060019; GO:0060170 16331 XR_003825775.2 42 2 27 5 209 NA NA NA NA NA NA 16332 XM_044314869.1 23 21 4 10 14 NA NA NA NA NA NA 16333 XM_044314092.1 14 0 16 5 73 NA NA NA NA NA NA 16334 XR_006395460.1 95 76 16 81 52 NA NA NA NA NA NA 16335 XM_044328771.1 0 0 0 2 6 NA NA NA NA NA NA 16336 XM_044325221.1 35 28 35 50 33 P47972 1.22e-25 Neuronal pentraxin-2 (NP2) (Neuronal pentraxin II) (NP-II) Homo sapiens (Human) associative learning [GO:0008306]; chemical synaptic transmission [GO:0007268]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962] GO:0005576; GO:0007268; GO:0008306; GO:0030246; GO:0046872; GO:0098962; GO:0098978 16337 XM_029330267.2 700 473 439 366 662 NA NA NA NA NA NA 16338 XR_006393003.1 41 2 25 5 151 NA NA NA NA NA NA 16339 XM_029339283.2 148 298 134 649 52 NA NA NA NA NA NA 16340 XM_044321890.1 4024 4903 1903 3815 3395 Q9C102 0 Glutamate synthase [NADH] (EC 1.4.1.14) (Glutamine-oxoglutarate aminotransferase) (GOGAT) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) ammonia assimilation cycle [GO:0019676]; glutamate biosynthetic process [GO:0006537]; L-glutamate biosynthetic process [GO:0097054] GO:0005506; GO:0005739; GO:0005829; GO:0006537; GO:0010181; GO:0015930; GO:0016040; GO:0016491; GO:0019676; GO:0050660; GO:0051538; GO:0097054 16341 XM_044321890.1 4024 4903 1903 3815 3395 Q9C102 5.6e-158 Glutamate synthase [NADH] (EC 1.4.1.14) (Glutamine-oxoglutarate aminotransferase) (GOGAT) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) ammonia assimilation cycle [GO:0019676]; glutamate biosynthetic process [GO:0006537]; L-glutamate biosynthetic process [GO:0097054] GO:0005506; GO:0005739; GO:0005829; GO:0006537; GO:0010181; GO:0015930; GO:0016040; GO:0016491; GO:0019676; GO:0050660; GO:0051538; GO:0097054 16342 XM_029336599.2 25 28 10 27 19 P19579 7.87e-30 Capsule biosynthesis protein CapA Bacillus anthracis capsule polysaccharide biosynthetic process [GO:0045227] GO:0005886; GO:0045227 16343 XM_029340870.2 858 268 169 255 622 P43247 0 DNA mismatch repair protein Msh2 (MutS protein homolog 2) Mus musculus (Mouse) B cell differentiation [GO:0030183]; B cell mediated immunity [GO:0019724]; cellular response to DNA damage stimulus [GO:0006974]; determination of adult lifespan [GO:0008340]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; germ cell development [GO:0007281]; in utero embryonic development [GO:0001701]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; isotype switching [GO:0045190]; maintenance of DNA repeat elements [GO:0043570]; male gonad development [GO:0008584]; mismatch repair [GO:0006298]; mitotic intra-S DNA damage checkpoint signaling [GO:0031573]; mitotic recombination [GO:0006312]; negative regulation of DNA recombination [GO:0045910]; negative regulation of neuron apoptotic process [GO:0043524]; oxidative phosphorylation [GO:0006119]; positive regulation of helicase activity [GO:0051096]; positive regulation of isotype switching to IgA isotypes [GO:0048298]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; postreplication repair [GO:0006301]; protein localization to chromatin [GO:0071168]; regulation of cell cycle [GO:0051726]; response to UV-B [GO:0010224]; response to X-ray [GO:0010165]; somatic hypermutation of immunoglobulin genes [GO:0016446]; somatic recombination of immunoglobulin gene segments [GO:0016447]; somatic recombination of immunoglobulin genes involved in immune response [GO:0002204] GO:0000287; GO:0000400; GO:0001701; GO:0002204; GO:0003677; GO:0003682; GO:0003684; GO:0003690; GO:0003697; GO:0005524; GO:0005634; GO:0005654; GO:0005694; GO:0006119; GO:0006281; GO:0006298; GO:0006301; GO:0006302; GO:0006312; GO:0006974; GO:0007281; GO:0008022; GO:0008094; GO:0008340; GO:0008584; GO:0008630; GO:0010165; GO:0010224; GO:0016446; GO:0016447; GO:0016887; GO:0019237; GO:0019724; GO:0019899; GO:0019901; GO:0030183; GO:0030983; GO:0031573; GO:0032137; GO:0032139; GO:0032142; GO:0032143; GO:0032181; GO:0032301; GO:0032302; GO:0032357; GO:0032405; GO:0042771; GO:0042803; GO:0043524; GO:0043531; GO:0043570; GO:0045190; GO:0045910; GO:0048298; GO:0048304; GO:0051096; GO:0051726; GO:0071168; GO:0140664 16344 XM_044321509.1 315 129 99 148 188 Q8TEA7 0 TBC domain-containing protein kinase-like protein Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; activation of GTPase activity [GO:0090630]; cell population proliferation [GO:0008283]; regulation of TOR signaling [GO:0032006] GO:0004672; GO:0005096; GO:0005524; GO:0005737; GO:0008283; GO:0030036; GO:0030496; GO:0032006; GO:0072686; GO:0090630 16345 XM_044313876.1 36 31 28 23 72 Q80XJ3 2.55e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 16346 XM_029342929.2 221 66 95 133 210 NA NA NA NA NA NA 16347 XM_044311250.1 8 0 7 1 55 A2AJ76 5.73e-27 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 16348 XM_044311250.1 8 0 7 1 55 A2AJ76 9.2e-25 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 16349 XM_044311250.1 8 0 7 1 55 A2AJ76 1.28e-22 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 16350 XM_044311250.1 8 0 7 1 55 A2AJ76 2.95e-22 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 16351 XM_044311250.1 8 0 7 1 55 A2AJ76 3.67e-22 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 16352 XM_044311250.1 8 0 7 1 55 A2AJ76 5.86e-21 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 16353 XM_044315748.1 874 624 480 976 1445 A0A0R4IC37 0 Cleavage and polyadenylation specificity factor subunit 1 (Cleavage and polyadenylation specific factor 1) Danio rerio (Zebrafish) (Brachydanio rerio) definitive hemopoiesis [GO:0060216]; mRNA polyadenylation [GO:0006378]; retinal ganglion cell axon guidance [GO:0031290] GO:0003676; GO:0005634; GO:0005654; GO:0005847; GO:0006378; GO:0031290; GO:0060216 16354 XM_029343912.2 77 38 78 51 189 Q9EQD2 2.06e-37 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 16355 XM_029325024.2 407 264 287 369 316 Q99JY4 5.12e-101 TraB domain-containing protein Mus musculus (Mouse) NA NA 16356 XM_029335859.2 1038 1262 808 894 597 Q9HA64 4.64e-130 Ketosamine-3-kinase (EC 2.7.1.172) (Fructosamine-3-kinase-related protein) (FN3K-RP) (FN3K-related protein) (Protein-psicosamine 3-kinase FN3KRP) (EC 2.7.1.-) Homo sapiens (Human) phosphorylation [GO:0016310]; post-translational protein modification [GO:0043687] GO:0005524; GO:0005829; GO:0016301; GO:0016310; GO:0043687; GO:0102193 16357 XM_044325415.1 270 112 115 646 475 NA NA NA NA NA NA 16358 XM_044314973.1 14 12 18 2 17 NA NA NA NA NA NA 16359 XR_006396521.1 5 5 14 9 75 NA NA NA NA NA NA 16360 XM_029336304.2 1931 4023 2545 2187 2087 Q8BJ56 7.19e-63 Patatin-like phospholipase domain-containing protein 2 (EC 3.1.1.3) (Adipose triglyceride lipase) (Calcium-independent phospholipase A2-zeta) (iPLA2-zeta) (EC 3.1.1.4) (Desnutrin) Mus musculus (Mouse) cellular lipid catabolic process [GO:0044242]; diacylglycerol biosynthetic process [GO:0006651]; lipid droplet disassembly [GO:1905691]; lipid droplet organization [GO:0034389]; lipid homeostasis [GO:0055088]; lipid storage [GO:0019915]; negative regulation of sequestering of triglyceride [GO:0010891]; positive regulation of triglyceride catabolic process [GO:0010898]; triglyceride catabolic process [GO:0019433] GO:0004623; GO:0004806; GO:0005654; GO:0005737; GO:0005811; GO:0005829; GO:0005886; GO:0006651; GO:0010891; GO:0010898; GO:0016020; GO:0016411; GO:0019433; GO:0019915; GO:0034389; GO:0044242; GO:0050253; GO:0051264; GO:0051265; GO:0055088; GO:1905691 16361 XM_044316914.1 93 129 176 404 408 Q6DIR8 0 Paladin Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005829 16362 XM_044322563.1 168 62 27 185 34 NA NA NA NA NA NA 16363 XM_044317886.1 145 544 12 3 47 Q9CWQ2 1.07e-29 Zinc finger SWIM domain-containing protein 7 (SWIM domain-containing and Srs2-interacting protein 1 homolog) Mus musculus (Mouse) double-strand break repair via homologous recombination [GO:0000724]; protein stabilization [GO:0050821] GO:0000724; GO:0005634; GO:0008270; GO:0050821; GO:0097196 16364 XM_044313472.1 171 176 76 198 103 NA NA NA NA NA NA 16365 XM_029344417.2 371 289 181 368 342 A8QMS7 6.61e-36 Myeloid differentiation primary response protein MyD88 Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) inflammatory response [GO:0006954]; innate immune response [GO:0045087]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123] GO:0002755; GO:0005737; GO:0006954; GO:0043123; GO:0045087; GO:0070976 16366 XM_029354879.2 55 626 0 110 0 NA NA NA NA NA NA 16367 XM_044326353.1 2 1 7 0 1 O62809 6.21e-30 Orexin receptor type 2 (Ox-2-R) (Ox2-R) (Ox2R) (Hypocretin receptor type 2) Sus scrofa (Pig) circadian sleep/wake cycle process [GO:0022410]; feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; locomotion [GO:0040011]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; regulation of circadian sleep/wake cycle, wakefulness [GO:0010840]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0004930; GO:0005886; GO:0007186; GO:0007200; GO:0007218; GO:0007631; GO:0010840; GO:0016499; GO:0022410; GO:0040011; GO:0051480 16368 XM_044309802.1 7 10 15 20 7 NA NA NA NA NA NA 16369 XM_029345440.2 0 0 0 14 0 P55112 2.1e-40 Zinc metalloproteinase nas-4 (EC 3.4.24.-) (Nematode astacin 4) Caenorhabditis elegans proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0006508; GO:0008270 16370 XM_044319178.1 842 493 302 706 419 A6QLU6 2.8e-64 Adhesion G-protein coupled receptor D1 (G-protein coupled receptor 133) Bos taurus (Bovine) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0005886; GO:0007166; GO:0007186; GO:0007189 16371 XM_029337536.2 0 0 35 18 177 Q9YHV3 1.89e-33 Noggin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cartilage development [GO:0051216]; cloaca development [GO:0035844]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic viscerocranium morphogenesis [GO:0048703]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell differentiation [GO:0045596]; osteoblast differentiation [GO:0001649]; pronephros development [GO:0048793] GO:0001649; GO:0005615; GO:0007368; GO:0009953; GO:0030514; GO:0035844; GO:0045596; GO:0048703; GO:0048793; GO:0051216 16372 XM_029350991.2 10050 7197 4689 7973 7416 NA NA NA NA NA NA 16373 XM_044325225.1 8 3 0 3 0 NA NA NA NA NA NA 16374 XR_006394603.1 195 177 66 73 137 NA NA NA NA NA NA 16375 XM_044328380.1 0 0 0 37 2 NA NA NA NA NA NA 16376 XM_044308391.1 184 54 289 13 909 NA NA NA NA NA NA 16377 XM_029344169.2 3840 1789 1480 3450 2247 Q58D55 0 Beta-galactosidase (EC 3.2.1.23) (Acid beta-galactosidase) (Lactase) Bos taurus (Bovine) carbohydrate metabolic process [GO:0005975] GO:0004565; GO:0005764; GO:0005975 16378 XR_006392162.1 2 2 10 93 47 NA NA NA NA NA NA 16379 XM_029350103.2 1015 759 228 836 655 O95551 1.69e-72 Tyrosyl-DNA phosphodiesterase 2 (Tyr-DNA phosphodiesterase 2) (hTDP2) (EC 3.1.4.-) (5'-tyrosyl-DNA phosphodiesterase) (5'-Tyr-DNA phosphodiesterase) (ETS1-associated protein 2) (ETS1-associated protein II) (EAPII) (TRAF and TNF receptor-associated protein) (Tyrosyl-RNA phosphodiesterase) (VPg unlinkase) Homo sapiens (Human) cell surface receptor signaling pathway [GO:0007166]; double-strand break repair [GO:0006302]; neuron development [GO:0048666] GO:0000287; GO:0003697; GO:0003714; GO:0004518; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0006302; GO:0007166; GO:0016235; GO:0016604; GO:0016605; GO:0030145; GO:0036317; GO:0048666; GO:0070260 16380 XR_006391992.1 18 0 23 10 24 NA NA NA NA NA NA 16381 XR_006392469.1 3 5 0 0 41 NA NA NA NA NA NA 16382 XM_029344683.2 0 252 0 57 0 Q9CYL5 1.92e-24 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Mus musculus (Mouse) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070374 16383 XM_044317076.1 0 2 0 0 17 P10079 1.69e-96 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 16384 XM_044317076.1 0 2 0 0 17 P10079 1.64e-95 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 16385 XM_044317076.1 0 2 0 0 17 P10079 3.48e-95 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 16386 XM_044317076.1 0 2 0 0 17 P10079 8.54e-84 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 16387 XM_044317076.1 0 2 0 0 17 P10079 3.23e-83 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 16388 XM_044317076.1 0 2 0 0 17 P10079 1.04e-69 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 16389 XM_044317076.1 0 2 0 0 17 P10079 2.89e-65 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 16390 XR_006392431.1 2 0 6 1 12 NA NA NA NA NA NA 16391 XM_029335990.2 137 59 26 118 36 P49815 0 Tuberin (Tuberous sclerosis 2 protein) Homo sapiens (Human) anoikis [GO:0043276]; endocytosis [GO:0006897]; heart development [GO:0007507]; insulin-like growth factor receptor signaling pathway [GO:0048009]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of mitophagy [GO:1901525]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of Wnt signaling pathway [GO:0030178]; neural tube closure [GO:0001843]; positive chemotaxis [GO:0050918]; positive regulation of GTPase activity [GO:0043547]; positive regulation of macroautophagy [GO:0016239]; protein import into nucleus [GO:0006606]; protein kinase B signaling [GO:0043491]; protein localization [GO:0008104]; regulation of cell cycle [GO:0051726]; regulation of endocytosis [GO:0030100]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of small GTPase mediated signal transduction [GO:0051056]; vesicle-mediated transport [GO:0016192] GO:0001843; GO:0005096; GO:0005634; GO:0005737; GO:0005764; GO:0005794; GO:0005829; GO:0006469; GO:0006606; GO:0006897; GO:0007507; GO:0008104; GO:0008285; GO:0014067; GO:0014069; GO:0016020; GO:0016192; GO:0016239; GO:0019902; GO:0030100; GO:0030178; GO:0031267; GO:0032007; GO:0033596; GO:0042803; GO:0043276; GO:0043491; GO:0043547; GO:0046626; GO:0046627; GO:0048009; GO:0048471; GO:0050918; GO:0051056; GO:0051726; GO:0051879; GO:0051898; GO:1901525 16392 XM_029335990.2 137 59 26 118 36 P49815 4.48e-83 Tuberin (Tuberous sclerosis 2 protein) Homo sapiens (Human) anoikis [GO:0043276]; endocytosis [GO:0006897]; heart development [GO:0007507]; insulin-like growth factor receptor signaling pathway [GO:0048009]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of mitophagy [GO:1901525]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of Wnt signaling pathway [GO:0030178]; neural tube closure [GO:0001843]; positive chemotaxis [GO:0050918]; positive regulation of GTPase activity [GO:0043547]; positive regulation of macroautophagy [GO:0016239]; protein import into nucleus [GO:0006606]; protein kinase B signaling [GO:0043491]; protein localization [GO:0008104]; regulation of cell cycle [GO:0051726]; regulation of endocytosis [GO:0030100]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of small GTPase mediated signal transduction [GO:0051056]; vesicle-mediated transport [GO:0016192] GO:0001843; GO:0005096; GO:0005634; GO:0005737; GO:0005764; GO:0005794; GO:0005829; GO:0006469; GO:0006606; GO:0006897; GO:0007507; GO:0008104; GO:0008285; GO:0014067; GO:0014069; GO:0016020; GO:0016192; GO:0016239; GO:0019902; GO:0030100; GO:0030178; GO:0031267; GO:0032007; GO:0033596; GO:0042803; GO:0043276; GO:0043491; GO:0043547; GO:0046626; GO:0046627; GO:0048009; GO:0048471; GO:0050918; GO:0051056; GO:0051726; GO:0051879; GO:0051898; GO:1901525 16393 XM_029344222.2 1841 1474 640 1046 935 P42700 0 RNA-binding protein RO60 (60 kDa SS-A/Ro ribonucleoprotein) (60 kDa Ro protein) (60 kDa ribonucleoprotein Ro) (RoRNP) (TROVE domain family member 2) Xenopus laevis (African clawed frog) cell projection organization [GO:0030030] GO:0005737; GO:0030030; GO:0034336; GO:0046872; GO:1990904 16394 XM_044308992.1 0 4 2 9 0 NA NA NA NA NA NA 16395 XR_003827691.2 139 195 142 172 122 NA NA NA NA NA NA 16396 XM_029326531.2 164 28 27 68 76 NA NA NA NA NA NA 16397 XM_044307824.1 3 0 6 170 3 NA NA NA NA NA NA 16398 XM_044309614.1 8 0 1 0 0 NA NA NA NA NA NA 16399 XM_044311747.1 13 14 10 11 32 Q96AY4 1.04e-103 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16400 XM_044311747.1 13 14 10 11 32 Q96AY4 1.87e-99 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16401 XM_044311747.1 13 14 10 11 32 Q96AY4 9.11e-97 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16402 XM_044311747.1 13 14 10 11 32 Q96AY4 6.87e-91 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16403 XM_044311747.1 13 14 10 11 32 Q96AY4 6.36e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16404 XM_029328310.2 158 12 26 81 97 NA NA NA NA NA NA 16405 XM_029339260.2 592 459 258 689 714 Q68F38 0 Protein VAC14 homolog Xenopus laevis (African clawed frog) phosphatidylinositol biosynthetic process [GO:0006661] GO:0005783; GO:0006661; GO:0010008; GO:0070772 16406 XR_006396415.1 31 27 5 52 9 NA NA NA NA NA NA 16407 XR_006393571.1 7 1 26 0 40 NA NA NA NA NA NA 16408 XM_044319631.1 17 1 21 9 20 NA NA NA NA NA NA 16409 XM_029332057.2 145 43 32 0 141 P52624 1.54e-88 Uridine phosphorylase 1 (UPase 1) (UrdPase 1) (EC 2.4.2.3) Mus musculus (Mouse) cellular response to glucose starvation [GO:0042149]; CMP catabolic process [GO:0006248]; dCMP catabolic process [GO:0006249]; dTMP catabolic process [GO:0046074]; dUMP catabolic process [GO:0046079]; pyrimidine nucleotide metabolic process [GO:0006220]; UMP catabolic process [GO:0046050]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]; uridine metabolic process [GO:0046108] GO:0004850; GO:0005654; GO:0005829; GO:0006218; GO:0006220; GO:0006248; GO:0006249; GO:0009032; GO:0042149; GO:0042802; GO:0044206; GO:0046050; GO:0046074; GO:0046079; GO:0046108; GO:0047847 16410 XM_044312629.1 2 6 15 0 41 NA NA NA NA NA NA 16411 XM_044314506.1 12 6 0 6 2 NA NA NA NA NA NA 16412 XM_029347542.2 26 0 0 69 0 NA NA NA NA NA NA 16413 XM_044324654.1 4448 4345 3644 4144 4419 P08775 0 DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit) Mus musculus (Mouse) cellular response to oxygen levels [GO:0071453]; DNA-templated transcription termination [GO:0006353]; positive regulation of RNA splicing [GO:0033120]; response to organic cyclic compound [GO:0014070]; transcription by RNA polymerase II [GO:0006366] GO:0000791; GO:0000974; GO:0001046; GO:0003677; GO:0003899; GO:0005634; GO:0005654; GO:0005665; GO:0005737; GO:0006353; GO:0006366; GO:0008022; GO:0014070; GO:0019900; GO:0031625; GO:0033120; GO:0046872; GO:0071453; GO:1990841 16414 XM_029332971.2 2299 2753 1713 2910 1543 B0YN54 8.95e-51 Glycolipid transfer protein (GLTP) Pan troglodytes (Chimpanzee) ceramide transport [GO:0035627]; intermembrane lipid transfer [GO:0120009] GO:0005829; GO:0035627; GO:0120009; GO:1902387; GO:1902388 16415 XM_044318613.1 57 75 66 68 130 Q92990 5.67e-53 Glomulin (FK506-binding protein-associated protein) (FAP) (FKBP-associated protein) Homo sapiens (Human) cell surface receptor signaling pathway [GO:0007166]; epigenetic regulation of gene expression [GO:0040029]; muscle cell differentiation [GO:0042692]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of T cell proliferation [GO:0042130]; neural tube closure [GO:0001843]; positive regulation of cytokine production [GO:0001819]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of phosphorylation [GO:0042327]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]; vasculogenesis [GO:0001570] GO:0001570; GO:0001819; GO:0001843; GO:0005102; GO:0005171; GO:0005737; GO:0007166; GO:0008285; GO:0031461; GO:0031462; GO:0031463; GO:0031464; GO:0031625; GO:0032434; GO:0032743; GO:0040029; GO:0042130; GO:0042327; GO:0042692; GO:0055105 16416 XM_044313659.1 70 15 0 109 112 NA NA NA NA NA NA 16417 XM_029323545.2 2866 2359 2457 4321 2925 Q969T9 2.17e-21 WW domain-binding protein 2 (WBP-2) Homo sapiens (Human) cellular response to estrogen stimulus [GO:0071391]; establishment of protein localization to chromatin [GO:0071169]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of histone H3-K14 acetylation [GO:0071442]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of transcription by RNA polymerase II [GO:0045944]; progesterone receptor signaling pathway [GO:0050847]; response to estrogen [GO:0043627]; response to progesterone [GO:0032570]; transcription initiation-coupled chromatin remodeling [GO:0045815] GO:0000785; GO:0000978; GO:0003713; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0030331; GO:0031490; GO:0032570; GO:0033148; GO:0043627; GO:0045815; GO:0045893; GO:0045944; GO:0050847; GO:0071169; GO:0071391; GO:0071442 16418 XM_029357077.2 417 222 288 248 337 NA NA NA NA NA NA 16419 XM_044326610.1 1726 973 841 1436 1423 A6H690 0 IQ and AAA domain-containing protein 1-like (Protein IQCA1P1) Mus musculus (Mouse) NA GO:0005524; GO:0016887 16420 XM_029350650.2 740 631 444 790 1080 Q8WU90 4.41e-71 Zinc finger CCCH domain-containing protein 15 (DRG family-regulatory protein 1) (Likely ortholog of mouse immediate early response erythropoietin 4) Homo sapiens (Human) cytokine-mediated signaling pathway [GO:0019221]; cytoplasmic translation [GO:0002181]; positive regulation of GTPase activity [GO:0043547] GO:0002181; GO:0003723; GO:0005634; GO:0005829; GO:0019221; GO:0043547; GO:0045296; GO:0046872 16421 XM_029342471.2 24 134 78 282 171 NA NA NA NA NA NA 16422 XM_029335699.2 5 8 5 7 1 NA NA NA NA NA NA 16423 XR_006391294.1 22 32 52 34 13 NA NA NA NA NA NA 16424 XM_029326377.2 72 63 159 195 192 NA NA NA NA NA NA 16425 XM_044321022.1 482 252 239 388 400 Q8N806 3.2e-117 Putative E3 ubiquitin-protein ligase UBR7 (EC 2.3.2.27) (N-recognin-7) (RING-type E3 ubiquitin transferase UBR7) Homo sapiens (Human) NA GO:0008270; GO:0061630 16426 XM_044308997.1 34 10 50 174 37 NA NA NA NA NA NA 16427 XM_044325108.1 13 25 13 12 0 NA NA NA NA NA NA 16428 XM_044312419.1 16 11 0 9 0 NA NA NA NA NA NA 16429 XM_044316289.1 257 252 152 247 623 Q9H857 8.27e-48 5'-nucleotidase domain-containing protein 2 (EC 3.1.3.-) Homo sapiens (Human) NA GO:0008253; GO:0046872 16430 XM_044316289.1 257 252 152 247 623 Q9H857 3.71e-43 5'-nucleotidase domain-containing protein 2 (EC 3.1.3.-) Homo sapiens (Human) NA GO:0008253; GO:0046872 16431 XM_044314759.1 23 7 6 0 81 Q9Z2V5 4.9e-30 Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Histone deacetylase mHDA2) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-) Mus musculus (Mouse) aggresome assembly [GO:0070842]; axonal transport of mitochondrion [GO:0019896]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to misfolded protein [GO:0071218]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to topologically incorrect protein [GO:0035967]; cilium disassembly [GO:0061523]; collateral sprouting [GO:0048668]; dendritic spine morphogenesis [GO:0060997]; epigenetic regulation of gene expression [GO:0040029]; histone deacetylation [GO:0016575]; Hsp90 deacetylation [GO:0070846]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; mitochondrion localization [GO:0051646]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of protein-containing complex disassembly [GO:0043242]; negative regulation of proteolysis [GO:0045861]; negative regulation of transcription by RNA polymerase II [GO:0000122]; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:0061734]; peptidyl-lysine deacetylation [GO:0034983]; polyubiquitinated misfolded protein transport [GO:0070845]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of hydrogen peroxide-mediated programmed cell death [GO:1901300]; positive regulation of mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of tubulin deacetylation [GO:0090044]; protein deacetylation [GO:0006476]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; protein-containing complex disassembly [GO:0032984]; regulation of establishment of protein localization [GO:0070201]; regulation of fat cell differentiation [GO:0045598]; regulation of macroautophagy [GO:0016241]; regulation of mitochondrion organization [GO:0010821]; regulation of protein stability [GO:0031647]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]; response to dexamethasone [GO:0071548]; response to growth factor [GO:0070848]; response to immobilization stress [GO:0035902]; response to misfolded protein [GO:0051788]; tubulin deacetylation [GO:0090042]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] GO:0000118; GO:0000122; GO:0000209; GO:0000978; GO:0001222; GO:0001975; GO:0003779; GO:0004407; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0005829; GO:0005874; GO:0005875; GO:0005901; GO:0006476; GO:0006511; GO:0006515; GO:0006886; GO:0007026; GO:0008013; GO:0008017; GO:0008270; GO:0010634; GO:0010821; GO:0015630; GO:0016234; GO:0016235; GO:0016241; GO:0016575; GO:0019896; GO:0030424; GO:0030425; GO:0031252; GO:0031333; GO:0031593; GO:0031625; GO:0031647; GO:0031648; GO:0032418; GO:0032984; GO:0032991; GO:0033138; GO:0033558; GO:0034983; GO:0035902; GO:0035967; GO:0036064; GO:0040029; GO:0042826; GO:0042903; GO:0043005; GO:0043014; GO:0043025; GO:0043130; GO:0043162; GO:0043204; GO:0043242; GO:0045598; GO:0045861; GO:0048156; GO:0048471; GO:0048487; GO:0048668; GO:0048843; GO:0050775; GO:0051412; GO:0051646; GO:0051787; GO:0051788; GO:0051879; GO:0051968; GO:0060997; GO:0061523; GO:0061734; GO:0070201; GO:0070301; GO:0070840; GO:0070842; GO:0070845; GO:0070846; GO:0070848; GO:0071218; GO:0071374; GO:0071548; GO:0090042; GO:0090044; GO:0098779; GO:1901300; GO:1901984; GO:1903223; GO:1904056; GO:1904115; GO:2000273 16432 XM_044314759.1 23 7 6 0 81 Q9Z2V5 4.9e-30 Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Histone deacetylase mHDA2) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-) Mus musculus (Mouse) aggresome assembly [GO:0070842]; axonal transport of mitochondrion [GO:0019896]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to misfolded protein [GO:0071218]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to topologically incorrect protein [GO:0035967]; cilium disassembly [GO:0061523]; collateral sprouting [GO:0048668]; dendritic spine morphogenesis [GO:0060997]; epigenetic regulation of gene expression [GO:0040029]; histone deacetylation [GO:0016575]; Hsp90 deacetylation [GO:0070846]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; mitochondrion localization [GO:0051646]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of protein-containing complex disassembly [GO:0043242]; negative regulation of proteolysis [GO:0045861]; negative regulation of transcription by RNA polymerase II [GO:0000122]; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:0061734]; peptidyl-lysine deacetylation [GO:0034983]; polyubiquitinated misfolded protein transport [GO:0070845]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of hydrogen peroxide-mediated programmed cell death [GO:1901300]; positive regulation of mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of tubulin deacetylation [GO:0090044]; protein deacetylation [GO:0006476]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; protein-containing complex disassembly [GO:0032984]; regulation of establishment of protein localization [GO:0070201]; regulation of fat cell differentiation [GO:0045598]; regulation of macroautophagy [GO:0016241]; regulation of mitochondrion organization [GO:0010821]; regulation of protein stability [GO:0031647]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]; response to dexamethasone [GO:0071548]; response to growth factor [GO:0070848]; response to immobilization stress [GO:0035902]; response to misfolded protein [GO:0051788]; tubulin deacetylation [GO:0090042]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] GO:0000118; GO:0000122; GO:0000209; GO:0000978; GO:0001222; GO:0001975; GO:0003779; GO:0004407; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0005829; GO:0005874; GO:0005875; GO:0005901; GO:0006476; GO:0006511; GO:0006515; GO:0006886; GO:0007026; GO:0008013; GO:0008017; GO:0008270; GO:0010634; GO:0010821; GO:0015630; GO:0016234; GO:0016235; GO:0016241; GO:0016575; GO:0019896; GO:0030424; GO:0030425; GO:0031252; GO:0031333; GO:0031593; GO:0031625; GO:0031647; GO:0031648; GO:0032418; GO:0032984; GO:0032991; GO:0033138; GO:0033558; GO:0034983; GO:0035902; GO:0035967; GO:0036064; GO:0040029; GO:0042826; GO:0042903; GO:0043005; GO:0043014; GO:0043025; GO:0043130; GO:0043162; GO:0043204; GO:0043242; GO:0045598; GO:0045861; GO:0048156; GO:0048471; GO:0048487; GO:0048668; GO:0048843; GO:0050775; GO:0051412; GO:0051646; GO:0051787; GO:0051788; GO:0051879; GO:0051968; GO:0060997; GO:0061523; GO:0061734; GO:0070201; GO:0070301; GO:0070840; GO:0070842; GO:0070845; GO:0070846; GO:0070848; GO:0071218; GO:0071374; GO:0071548; GO:0090042; GO:0090044; GO:0098779; GO:1901300; GO:1901984; GO:1903223; GO:1904056; GO:1904115; GO:2000273 16433 XM_029345937.2 55 55 29 24 88 NA NA NA NA NA NA 16434 XM_044321703.1 59 0 0 0 0 B6CHA3 0 E3 ubiquitin-protein ligase UHRF1 (EC 2.3.2.27) (Nuclear zinc finger protein Np95) (XNp95) (RING-type E3 ubiquitin transferase UHRF1) (Ubiquitin-like PHD and RING finger domain-containing protein 1) (Ubiquitin-like-containing PHD and RING finger domains protein 1) Xenopus laevis (African clawed frog) cell cycle [GO:0007049]; chromatin organization [GO:0006325]; histone ubiquitination [GO:0016574]; maintenance of DNA methylation [GO:0010216]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein autoubiquitination [GO:0051865]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000122; GO:0000785; GO:0000791; GO:0000792; GO:0004842; GO:0005634; GO:0005657; GO:0006325; GO:0006511; GO:0007049; GO:0008270; GO:0010216; GO:0016574; GO:0035064; GO:0042393; GO:0044729; GO:0051865 16435 XR_003824723.2 280 303 0 27 177 NA NA NA NA NA NA 16436 XM_044322926.1 11 32 0 6 14 NA NA NA NA NA NA 16437 XR_006396482.1 0 0 0 0 29 NA NA NA NA NA NA 16438 XM_044310780.1 24 22 10 0 5 NA NA NA NA NA NA 16439 XM_029338094.2 216 303 97 169 143 NA NA NA NA NA NA 16440 XM_029340038.2 4148 3944 1621 3492 1547 P03967 1.51e-33 Ras-like protein rasD (EC 3.6.5.2) (Transforming protein p23 homolog) Dictyostelium discoideum (Social amoeba) adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway [GO:0140582]; chemotaxis [GO:0006935]; MAPK cascade [GO:0000165]; mitotic cytokinesis [GO:0000281]; phototaxis [GO:0042331]; Ras protein signal transduction [GO:0007265]; response to bacterium [GO:0009617]; thermotaxis [GO:0043052] GO:0000165; GO:0000281; GO:0003924; GO:0003925; GO:0004860; GO:0005525; GO:0005811; GO:0005829; GO:0005886; GO:0006935; GO:0007265; GO:0009617; GO:0019003; GO:0019887; GO:0042331; GO:0043052; GO:0140582 16441 XM_029351342.2 288 160 119 101 219 Q4KLT0 8.64e-56 E3 ubiquitin-protein ligase RNF217 (EC 2.3.2.31) (RING finger protein 217) Xenopus laevis (African clawed frog) NA GO:0004842; GO:0005737; GO:0016020; GO:0046872 16442 XM_044320945.1 741 1087 537 849 476 Q6DMN8 1.09e-56 Spermatogenesis-associated protein 4 Pan troglodytes (Chimpanzee) regulation of cytoskeleton organization [GO:0051493] GO:0005634; GO:0005930; GO:0008017; GO:0051493 16443 XM_044313887.1 43 0 75 2 3 NA NA NA NA NA NA 16444 XM_029342959.2 584 162 322 266 209 G5EBQ8 2.6e-113 Chitin synthase chs-2 (EC 2.4.1.16) (Chitin-UDP acetyl-glucosaminyl transferase chs-2) Caenorhabditis elegans cell wall chitin biosynthetic process [GO:0006038]; chitin biosynthetic process [GO:0006031]; positive regulation of nematode larval development [GO:0061063] GO:0004100; GO:0005886; GO:0006031; GO:0006038; GO:0030428; GO:0061063; GO:0071944 16445 XM_044324659.1 1004 390 287 1108 0 Q63406 4.98e-148 Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2-transforming sequence-like protein) (OST oncogene) Rattus norvegicus (Rat) positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of catalytic activity [GO:0050790]; Rho protein signal transduction [GO:0007266] GO:0005085; GO:0005545; GO:0005737; GO:0005886; GO:0007266; GO:0016020; GO:0019898; GO:0030027; GO:0035025; GO:0035091; GO:0045944; GO:0050790 16446 XM_044315048.1 6 28 6 0 4 NA NA NA NA NA NA 16447 XM_029339101.2 16 11 29 10 18 NA NA NA NA NA NA 16448 XR_003824437.2 317 120 140 388 345 NA NA NA NA NA NA 16449 XM_044310878.1 107 27 12 34 0 Q3UQ28 2.68e-32 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 16450 XM_044310878.1 107 27 12 34 0 Q3UQ28 4.29e-29 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 16451 XM_029332711.2 60 74 11 74 11 Q2KJ63 1.97e-63 Plasma kallikrein (EC 3.4.21.34) (Fletcher factor) (Kininogenin) (Plasma prekallikrein) [Cleaved into: Plasma kallikrein heavy chain; Plasma kallikrein light chain] Bos taurus (Bovine) blood coagulation [GO:0007596]; fibrinolysis [GO:0042730]; inflammatory response [GO:0006954]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919] GO:0004252; GO:0005615; GO:0006954; GO:0007596; GO:0031639; GO:0042730; GO:0042803; GO:0051919 16452 XM_029332987.2 1 0 0 14 5 NA NA NA NA NA NA 16453 XM_029346721.2 0 0 36 0 17 P49183 2.97e-78 Deoxyribonuclease-1 (EC 3.1.21.1) (Deoxyribonuclease I) (DNase I) Mus musculus (Mouse) apoptotic process [GO:0006915]; DNA catabolic process [GO:0006308]; DNA catabolic process, endonucleolytic [GO:0000737]; neutrophil activation involved in immune response [GO:0002283]; regulation of acute inflammatory response [GO:0002673]; regulation of neutrophil mediated cytotoxicity [GO:0070948] GO:0000737; GO:0002283; GO:0002673; GO:0003677; GO:0003779; GO:0004530; GO:0004536; GO:0005576; GO:0005634; GO:0005635; GO:0006308; GO:0006915; GO:0042588; GO:0070948 16454 XM_029330867.2 1417 1504 1351 1943 1534 Q10472 6.51e-153 Polypeptide N-acetylgalactosaminyltransferase 1 (EC 2.4.1.41) (Polypeptide GalNAc transferase 1) (GalNAc-T1) (pp-GaNTase 1) (Protein-UDP acetylgalactosaminyltransferase 1) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 1) [Cleaved into: Polypeptide N-acetylgalactosaminyltransferase 1 soluble form] Homo sapiens (Human) O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493]; protein O-linked glycosylation via serine [GO:0018242]; protein O-linked glycosylation via threonine [GO:0018243]; viral protein processing [GO:0019082] GO:0000139; GO:0004653; GO:0005576; GO:0005789; GO:0006493; GO:0016020; GO:0016266; GO:0018242; GO:0018243; GO:0019082; GO:0030145; GO:0030246; GO:0032580; GO:0033116; GO:0048471 16455 XM_044329188.1 47 31 10 8 43 NA NA NA NA NA NA 16456 XM_029344492.2 260 211 140 700 404 A6N6J5 0 WD repeat-containing protein 35 (Naofen) Rattus norvegicus (Rat) cellular response to glucose stimulus [GO:0071333]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to xenobiotic stimulus [GO:0071466]; cilium assembly [GO:0060271]; intraciliary retrograde transport [GO:0035721]; intraciliary transport [GO:0042073]; liver regeneration [GO:0097421]; negative regulation of gene expression [GO:0010629]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vasoconstriction [GO:0045907]; protein localization to cilium [GO:0061512]; response to lipopolysaccharide [GO:0032496]; response to toxic substance [GO:0009636] GO:0005737; GO:0005813; GO:0005930; GO:0009636; GO:0010629; GO:0030991; GO:0032496; GO:0035721; GO:0036064; GO:0042073; GO:0043065; GO:0043280; GO:0045019; GO:0045907; GO:0060271; GO:0061512; GO:0071333; GO:0071356; GO:0071466; GO:0090200; GO:0097421; GO:1990830 16457 XM_044307602.1 83 22 56 203 156 NA NA NA NA NA NA 16458 XM_029342147.2 300 200 108 162 162 NA NA NA NA NA NA 16459 XM_044321496.1 0 310 64 115 52 Q01804 3.47e-71 OTU domain-containing protein 4 (EC 3.4.19.12) (HIV-1-induced protein HIN-1) Homo sapiens (Human) innate immune response [GO:0045087]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; positive regulation of DNA demethylation [GO:1901537]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; regulation of protein K48-linked deubiquitination [GO:1903093] GO:0003723; GO:0004843; GO:0005634; GO:0005829; GO:0016579; GO:0034122; GO:0045087; GO:0060090; GO:0061578; GO:0070536; GO:0071108; GO:1901537; GO:1903093; GO:2000660 16460 XM_044306769.1 39 6 57 38 78 Q7RTR2 1.33e-35 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16461 XM_044306769.1 39 6 57 38 78 Q7RTR2 4.21e-33 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16462 XM_044306769.1 39 6 57 38 78 Q7RTR2 4.04e-32 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16463 XM_044306769.1 39 6 57 38 78 Q7RTR2 4.48e-31 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16464 XM_044306769.1 39 6 57 38 78 Q7RTR2 7.29e-31 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16465 XM_044306769.1 39 6 57 38 78 Q7RTR2 2.65e-23 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16466 XR_006397820.1 55 4 13 16 25 NA NA NA NA NA NA 16467 XM_044326731.1 17 39 0 45 4 Q8VEG4 4.85e-47 Exonuclease 3'-5' domain-containing protein 2 (EC 3.1.11.1) (3'-5' exoribonuclease EXD2) (EC 3.1.13.-) (Exonuclease 3'-5' domain-like-containing protein 2) Mus musculus (Mouse) DNA double-strand break processing [GO:0000729]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; replication fork processing [GO:0031297] GO:0000175; GO:0000287; GO:0000724; GO:0000729; GO:0003676; GO:0005634; GO:0005737; GO:0005739; GO:0005741; GO:0005759; GO:0006302; GO:0008296; GO:0008310; GO:0008408; GO:0008852; GO:0030145; GO:0031297; GO:0042803; GO:0045111; GO:0090305; GO:0090734 16468 XM_044326731.1 17 39 0 45 4 Q8VEG4 1.99e-30 Exonuclease 3'-5' domain-containing protein 2 (EC 3.1.11.1) (3'-5' exoribonuclease EXD2) (EC 3.1.13.-) (Exonuclease 3'-5' domain-like-containing protein 2) Mus musculus (Mouse) DNA double-strand break processing [GO:0000729]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; replication fork processing [GO:0031297] GO:0000175; GO:0000287; GO:0000724; GO:0000729; GO:0003676; GO:0005634; GO:0005737; GO:0005739; GO:0005741; GO:0005759; GO:0006302; GO:0008296; GO:0008310; GO:0008408; GO:0008852; GO:0030145; GO:0031297; GO:0042803; GO:0045111; GO:0090305; GO:0090734 16469 XM_029333929.2 1035 914 347 557 715 O94889 6.78e-74 Kelch-like protein 18 Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; positive regulation of mitotic cell cycle phase transition [GO:1901992]; protein ubiquitination [GO:0016567] GO:0007049; GO:0016567; GO:0051301; GO:1901992 16470 XM_044328158.1 5 0 0 8 7 NA NA NA NA NA NA 16471 XM_029355403.2 65 42 33 59 70 NA NA NA NA NA NA 16472 XM_029351787.2 0 4 19 40 0 NA NA NA NA NA NA 16473 XM_044313442.1 78 26 102 80 98 NA NA NA NA NA NA 16474 XM_029335934.2 65 12 10 43 77 NA NA NA NA NA NA 16475 XR_003826883.2 36 34 53 89 56 NA NA NA NA NA NA 16476 XM_044310892.1 0 18 7 6 6 NA NA NA NA NA NA 16477 XM_029329740.2 382 330 195 463 420 NA NA NA NA NA NA 16478 XM_044310379.1 0 4 0 8 5 NA NA NA NA NA NA 16479 XR_006397407.1 0 13 26 11 3 NA NA NA NA NA NA 16480 XM_044307276.1 550 485 418 1042 832 NA NA NA NA NA NA 16481 XM_029337182.2 1184 1581 833 1648 967 NA NA NA NA NA NA 16482 XR_006393170.1 428 394 82 211 30 NA NA NA NA NA NA 16483 XR_006394248.1 23 11 20 83 27 NA NA NA NA NA NA 16484 XM_044321761.1 4778 2379 2880 4253 2649 O57656 8.59e-122 Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic (GPD-C) (GPDH-C) (EC 1.1.1.8) Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate catabolic process [GO:0046168] GO:0005975; GO:0009331; GO:0042803; GO:0046168; GO:0047952; GO:0051287 16485 XM_044314196.1 53 82 403 289 230 NA NA NA NA NA NA 16486 XR_006392916.1 41 2 25 5 151 NA NA NA NA NA NA 16487 XM_029339652.2 1012 785 501 658 390 Q9R0D8 3.53e-82 WD repeat-containing protein 54 Mus musculus (Mouse) negative regulation of receptor internalization [GO:0002091]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of MAPK cascade [GO:0043408] GO:0002091; GO:0031982; GO:0042058; GO:0042803; GO:0043408 16488 XM_029351299.2 829 616 445 1039 974 Q6NXR0 1.01e-59 Interferon-inducible GTPase 5 (EC 3.6.5.-) (Immunity-related GTPase cinema 1) Homo sapiens (Human) cellular response to interferon-beta [GO:0035458]; defense response [GO:0006952] GO:0003924; GO:0005525; GO:0005789; GO:0006952; GO:0035458 16489 XM_029337661.2 83 0 0 31 69 O88871 9.92e-118 Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51) Rattus norvegicus (Rat) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; gamma-aminobutyric acid signaling pathway [GO:0007214]; neuron-glial cell signaling [GO:0150099]; synaptic transmission, GABAergic [GO:0051932] GO:0004888; GO:0004965; GO:0005737; GO:0005886; GO:0007193; GO:0007214; GO:0016020; GO:0030425; GO:0038039; GO:0042734; GO:0043005; GO:0043204; GO:0045211; GO:0046982; GO:0051932; GO:0098978; GO:0098982; GO:0150099; GO:1902710; GO:1902712 16490 XR_006397044.1 0 0 18 8 0 NA NA NA NA NA NA 16491 XR_006394539.1 32 72 55 105 174 NA NA NA NA NA NA 16492 XM_029344191.2 88 242 63 81 61 NA NA NA NA NA NA 16493 XM_029348043.2 308 268 347 287 422 O43156 5.25e-169 TELO2-interacting protein 1 homolog (Protein SMG10) Homo sapiens (Human) chromatin remodeling [GO:0006338]; positive regulation of DNA damage checkpoint [GO:2000003]; protein stabilization [GO:0050821]; regulation of TOR signaling [GO:0032006] GO:0005634; GO:0005737; GO:0006338; GO:0031931; GO:0031932; GO:0032006; GO:0050821; GO:0070209; GO:0110078; GO:2000003 16494 XR_003826810.2 0 0 2 5 7 NA NA NA NA NA NA 16495 XM_029329506.2 833 378 308 664 710 Q9V727 7.63e-34 Polycomb protein Asx (Additional sex combs) Drosophila melanogaster (Fruit fly) animal organ morphogenesis [GO:0009887]; antennal development [GO:0007469]; anterior/posterior axis specification [GO:0009948]; apposition of dorsal and ventral imaginal disc-derived wing surfaces [GO:0007475]; cell fate determination [GO:0001709]; chromatin organization [GO:0006325]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression [GO:0010468]; regulation of transcription by RNA polymerase II [GO:0006357]; sex comb development [GO:0045498]; syncytial blastoderm mitotic cell cycle [GO:0035186] GO:0000785; GO:0001709; GO:0003677; GO:0003682; GO:0005634; GO:0006325; GO:0006357; GO:0007469; GO:0007475; GO:0009887; GO:0009948; GO:0010468; GO:0035186; GO:0035517; GO:0035522; GO:0035800; GO:0045498; GO:0045892; GO:0045893; GO:0045944; GO:0046872 16496 XM_044318964.1 0 107 0 0 114 NA NA NA NA NA NA 16497 XM_029337607.2 1315 1271 846 833 2236 Q91XE9 2.36e-39 Cyclic AMP-responsive element-binding protein 3-like protein 3 (cAMP-responsive element-binding protein 3-like protein 3) (Transcription factor CREB-H) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3-like protein 3] Mus musculus (Mouse) positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; regulation of transcription by RNA polymerase II [GO:0006357]; response to unfolded protein [GO:0006986] GO:0000976; GO:0000977; GO:0000978; GO:0000981; GO:0001228; GO:0005634; GO:0005654; GO:0005783; GO:0005789; GO:0005829; GO:0006357; GO:0006986; GO:0016020; GO:0042802; GO:0042803; GO:0045944; GO:0046982; GO:1990440 16498 XM_044316247.1 2342 1619 1467 2346 2175 Q9HAU5 0 Regulator of nonsense transcripts 2 (Up-frameshift suppressor 2 homolog) (hUpf2) Homo sapiens (Human) animal organ regeneration [GO:0031100]; liver development [GO:0001889]; mRNA export from nucleus [GO:0006406]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184] GO:0000184; GO:0001889; GO:0003723; GO:0005634; GO:0005737; GO:0005829; GO:0005844; GO:0006406; GO:0031100; GO:0035145; GO:0036464; GO:0042162; GO:0048471; GO:0060090 16499 XM_029331358.2 1318 952 660 1103 897 Q8BH01 1.38e-128 Transmembrane and coiled-coil domain-containing protein 3 Mus musculus (Mouse) NA GO:0015386; GO:0016020 16500 XM_044308606.1 129 25 282 138 0 Q96AY4 1.26e-110 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16501 XM_044308606.1 129 25 282 138 0 Q96AY4 1.63e-108 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16502 XM_044308606.1 129 25 282 138 0 Q96AY4 1.62e-104 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16503 XM_044308606.1 129 25 282 138 0 Q96AY4 2.75e-100 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16504 XM_044308606.1 129 25 282 138 0 Q96AY4 6.21e-98 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16505 XM_044308606.1 129 25 282 138 0 Q96AY4 2.61e-84 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16506 XM_044308606.1 129 25 282 138 0 Q96AY4 3.8e-70 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16507 XM_029334010.2 0 16 0 6 32 NA NA NA NA NA NA 16508 XM_044318980.1 345 476 311 243 26 P70196 2.4e-112 TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6) Mus musculus (Mouse) activation of NF-kappaB-inducing kinase activity [GO:0007250]; activation of protein kinase activity [GO:0032147]; animal organ morphogenesis [GO:0009887]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; bone remodeling [GO:0046849]; bone resorption [GO:0045453]; cell development [GO:0048468]; cellular response to cytokine stimulus [GO:0071345]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-17-mediated signaling pathway [GO:0097400]; JNK cascade [GO:0007254]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin production [GO:0002637]; response to interleukin-1 [GO:0070555]; signal transduction [GO:0007165]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000122; GO:0000209; GO:0001503; GO:0001701; GO:0001843; GO:0002637; GO:0002726; GO:0004842; GO:0005164; GO:0005634; GO:0005737; GO:0005811; GO:0005829; GO:0005886; GO:0005938; GO:0006955; GO:0006974; GO:0007165; GO:0007249; GO:0007250; GO:0007254; GO:0008270; GO:0009887; GO:0009898; GO:0016567; GO:0019221; GO:0019886; GO:0019901; GO:0030316; GO:0031435; GO:0031624; GO:0031625; GO:0031663; GO:0031666; GO:0031996; GO:0032147; GO:0032735; GO:0032743; GO:0032755; GO:0032813; GO:0032991; GO:0033209; GO:0035631; GO:0042088; GO:0042102; GO:0042475; GO:0042802; GO:0042826; GO:0042981; GO:0043011; GO:0043122; GO:0043123; GO:0043422; GO:0043507; GO:0045453; GO:0045672; GO:0045892; GO:0045944; GO:0046330; GO:0046849; GO:0047485; GO:0048468; GO:0048471; GO:0048661; GO:0050852; GO:0051091; GO:0051092; GO:0051865; GO:0061630; GO:0070498; GO:0070534; GO:0070555; GO:0071222; GO:0071345; GO:0097400; GO:1901224; GO:1904996; GO:2000679 16509 XM_029350615.2 353 1402 289 1608 719 NA NA NA NA NA NA 16510 XM_029335265.2 1179 954 882 1380 1630 Q61235 1.1e-144 Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin-3) (SNT3) (Syntrophin-like) (SNTL) Mus musculus (Mouse) NA GO:0003779; GO:0005198; GO:0005516; GO:0005654; GO:0005737; GO:0005794; GO:0005874; GO:0005886; GO:0016010; GO:0030658; GO:0032991; GO:0045202; GO:0070161 16511 XM_044322445.1 32 21 10 90 5 Q38PU2 5.83e-84 Glutamate receptor ionotropic, kainate 3 (GluK3) (Glutamate receptor 7) (GluR-7) (GluR7) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) G protein-coupled glutamate receptor signaling pathway [GO:0007216] GO:0001640; GO:0004970; GO:0007216; GO:0015277; GO:0043197; GO:0045211; GO:0098978; GO:0099507 16512 XM_029336937.2 890 501 451 420 539 Q80XJ3 2.38e-76 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 16513 XM_029336937.2 890 501 451 420 539 Q80XJ3 4.08e-73 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 16514 XM_029336937.2 890 501 451 420 539 Q80XJ3 1.11e-70 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 16515 XM_029336937.2 890 501 451 420 539 Q80XJ3 4.33e-70 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 16516 XM_029336937.2 890 501 451 420 539 Q80XJ3 1.71e-69 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 16517 XM_029336937.2 890 501 451 420 539 Q80XJ3 1.07e-68 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 16518 XM_029336937.2 890 501 451 420 539 Q80XJ3 1.37e-63 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 16519 XM_029336937.2 890 501 451 420 539 Q80XJ3 2.23e-57 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 16520 XM_029336937.2 890 501 451 420 539 Q80XJ3 5.36e-50 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 16521 XM_029336937.2 890 501 451 420 539 Q80XJ3 2.3e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 16522 XM_044309652.1 456 400 418 312 165 A0A3M6TIF0 0 NA NA NA NA 16523 XM_029334749.2 240 7 339 245 97 NA NA NA NA NA NA 16524 XM_029344242.2 22 106 3 15 55 Q4R863 4.17e-87 Protein-tyrosine sulfotransferase 2 (EC 2.8.2.20) (Tyrosylprotein sulfotransferase 2) (TPST-2) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) peptidyl-tyrosine sulfation [GO:0006478] GO:0000139; GO:0006478; GO:0008476 16525 XR_006392237.1 59 73 69 112 34 NA NA NA NA NA NA 16526 XM_029334234.2 29 3 7 7 21 Q9TXJ8 1.58e-48 Putative ATP-dependent DNA helicase Q1 (EC 3.6.4.12) Caenorhabditis elegans DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724] GO:0000724; GO:0003676; GO:0005524; GO:0005634; GO:0005694; GO:0005737; GO:0006268; GO:0006281; GO:0006310; GO:0009378; GO:0016887; GO:0032508; GO:0043138 16527 XM_029334152.2 810 663 239 427 239 NA NA NA NA NA NA 16528 XM_029348002.2 0 382 383 0 110 NA NA NA NA NA NA 16529 XM_044320171.1 709 818 292 672 244 Q5DTN8 9.24e-50 Janus kinase and microtubule-interacting protein 3 (Neuroendocrine long coiled-coil protein 2) Mus musculus (Mouse) NA GO:0005794; GO:0008017; GO:0019900 16530 XM_044315828.1 21 8 52 6 103 NA NA NA NA NA NA 16531 XM_044307044.1 1595 0 0 0 0 O75445 6.5e-115 Usherin (Usher syndrome type IIa protein) (Usher syndrome type-2A protein) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear receptor cell differentiation [GO:0060113]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0001917; GO:0002141; GO:0002142; GO:0005518; GO:0005576; GO:0005604; GO:0005737; GO:0007601; GO:0007605; GO:0009887; GO:0009888; GO:0016324; GO:0016477; GO:0017022; GO:0032391; GO:0032421; GO:0034446; GO:0035315; GO:0036064; GO:0042491; GO:0042802; GO:0045184; GO:0045494; GO:0048496; GO:0050896; GO:0050953; GO:0051649; GO:0060113; GO:0060171; GO:1990075; GO:1990696 16532 XM_029329119.2 4 4 0 6 3 NA NA NA NA NA NA 16533 XM_044308201.1 1121 644 410 1198 1090 Q9UBC2 1.14e-160 Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) Homo sapiens (Human) endocytosis [GO:0006897]; endosomal transport [GO:0016197] GO:0005509; GO:0005634; GO:0005829; GO:0005886; GO:0006897; GO:0016020; GO:0016197; GO:0030132; GO:0045296 16534 XM_029340860.2 10558 6268 2937 11530 4859 Q01196 8.13e-80 Runt-related transcription factor 1 (Acute myeloid leukemia 1 protein) (Core-binding factor subunit alpha-2) (CBF-alpha-2) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEA2-alpha B) (PEBP2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit) Homo sapiens (Human) cardiac muscle tissue regeneration [GO:0061026]; chondrocyte differentiation [GO:0002062]; hematopoietic stem cell proliferation [GO:0071425]; hemopoiesis [GO:0030097]; myeloid cell differentiation [GO:0030099]; myeloid leukocyte differentiation [GO:0002573]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron differentiation [GO:0030182]; ossification [GO:0001503]; peripheral nervous system neuron development [GO:0048935]; positive regulation of angiogenesis [GO:0045766]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extracellular matrix organization [GO:1903055]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of cell differentiation [GO:0045595]; regulation of connective tissue replacement [GO:1905203]; regulation of plasminogen activation [GO:0010755]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000785; GO:0000976; GO:0000977; GO:0000978; GO:0000981; GO:0001222; GO:0001223; GO:0001228; GO:0001503; GO:0002062; GO:0002573; GO:0003677; GO:0003700; GO:0005509; GO:0005524; GO:0005634; GO:0005654; GO:0006357; GO:0010755; GO:0016513; GO:0030097; GO:0030099; GO:0030182; GO:0030853; GO:0030854; GO:0032743; GO:0032967; GO:0042803; GO:0043231; GO:0043371; GO:0043378; GO:0045595; GO:0045766; GO:0045893; GO:0045944; GO:0046982; GO:0048935; GO:0060043; GO:0061026; GO:0071425; GO:0140297; GO:1903055; GO:1905203 16535 XR_006395388.1 0 40 8 15 21 NA NA NA NA NA NA 16536 XM_029338968.2 14 6 30 21 46 P10079 1.6e-45 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 16537 XM_029338968.2 14 6 30 21 46 P10079 1.6e-45 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 16538 XM_029338968.2 14 6 30 21 46 P10079 1.23e-42 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 16539 XM_029338968.2 14 6 30 21 46 P10079 1.23e-42 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 16540 XM_029338968.2 14 6 30 21 46 P10079 1.43e-42 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 16541 XM_029338968.2 14 6 30 21 46 P10079 5.98e-42 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 16542 XM_029338968.2 14 6 30 21 46 P10079 5.98e-42 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 16543 XM_029338968.2 14 6 30 21 46 P10079 1.92e-38 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 16544 XM_029338968.2 14 6 30 21 46 P10079 5.92e-38 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 16545 XM_029338968.2 14 6 30 21 46 P10079 1.72e-36 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 16546 XM_029338968.2 14 6 30 21 46 P10079 1.72e-36 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 16547 XM_029338968.2 14 6 30 21 46 P10079 3.56e-34 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 16548 XM_029338968.2 14 6 30 21 46 P10079 2.28e-21 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 16549 XM_044323609.1 7 0 3 0 9 NA NA NA NA NA NA 16550 XM_044307310.1 1507 452 607 1015 1130 NA NA NA NA NA NA 16551 XM_029347835.2 318 159 151 220 223 Q9UIF7 3.97e-130 Adenine DNA glycosylase (EC 3.2.2.31) (MutY homolog) (hMYH) Homo sapiens (Human) base-excision repair [GO:0006284]; depurination [GO:0045007]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]; negative regulation of necroptotic process [GO:0060546] GO:0000701; GO:0005634; GO:0005654; GO:0005739; GO:0006281; GO:0006284; GO:0006298; GO:0019104; GO:0032357; GO:0032407; GO:0034039; GO:0035485; GO:0045007; GO:0046872; GO:0051539; GO:0060546 16552 XM_029347114.2 98 81 78 99 80 Q12955 1.21e-103 Ankyrin-3 (ANK-3) (Ankyrin-G) Homo sapiens (Human) axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165] GO:0000281; GO:0005200; GO:0005764; GO:0005783; GO:0005794; GO:0005829; GO:0005886; GO:0007009; GO:0007165; GO:0007409; GO:0007528; GO:0008092; GO:0008093; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014704; GO:0014731; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030425; GO:0030507; GO:0030674; GO:0031594; GO:0033268; GO:0034112; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045184; GO:0045211; GO:0045296; GO:0045838; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:1900827; GO:1902260; GO:2000651; GO:2001259 16553 XM_029347114.2 98 81 78 99 80 Q12955 3.09e-100 Ankyrin-3 (ANK-3) (Ankyrin-G) Homo sapiens (Human) axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165] GO:0000281; GO:0005200; GO:0005764; GO:0005783; GO:0005794; GO:0005829; GO:0005886; GO:0007009; GO:0007165; GO:0007409; GO:0007528; GO:0008092; GO:0008093; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014704; GO:0014731; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030425; GO:0030507; GO:0030674; GO:0031594; GO:0033268; GO:0034112; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045184; GO:0045211; GO:0045296; GO:0045838; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:1900827; GO:1902260; GO:2000651; GO:2001259 16554 XM_029347114.2 98 81 78 99 80 Q12955 6.22e-90 Ankyrin-3 (ANK-3) (Ankyrin-G) Homo sapiens (Human) axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165] GO:0000281; GO:0005200; GO:0005764; GO:0005783; GO:0005794; GO:0005829; GO:0005886; GO:0007009; GO:0007165; GO:0007409; GO:0007528; GO:0008092; GO:0008093; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014704; GO:0014731; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030425; GO:0030507; GO:0030674; GO:0031594; GO:0033268; GO:0034112; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045184; GO:0045211; GO:0045296; GO:0045838; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:1900827; GO:1902260; GO:2000651; GO:2001259 16555 XM_029347114.2 98 81 78 99 80 Q12955 1.73e-47 Ankyrin-3 (ANK-3) (Ankyrin-G) Homo sapiens (Human) axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165] GO:0000281; GO:0005200; GO:0005764; GO:0005783; GO:0005794; GO:0005829; GO:0005886; GO:0007009; GO:0007165; GO:0007409; GO:0007528; GO:0008092; GO:0008093; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014704; GO:0014731; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030425; GO:0030507; GO:0030674; GO:0031594; GO:0033268; GO:0034112; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045184; GO:0045211; GO:0045296; GO:0045838; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:1900827; GO:1902260; GO:2000651; GO:2001259 16556 XM_044314809.1 4 32 16 0 6 NA NA NA NA NA NA 16557 XM_029350235.2 234 156 87 332 238 Q6UX65 1.87e-34 DNA damage-regulated autophagy modulator protein 2 (Transmembrane protein 77) Homo sapiens (Human) apoptotic process [GO:0006915]; autophagy [GO:0006914]; photoreceptor cell maintenance [GO:0045494]; regulation of autophagy [GO:0010506]; visual perception [GO:0007601] GO:0001917; GO:0005737; GO:0005764; GO:0005765; GO:0005794; GO:0006914; GO:0006915; GO:0007601; GO:0010506; GO:0016324; GO:0043231; GO:0045494 16558 XM_044310014.1 1571 0 0 1 0 P70490 2.61e-52 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 16559 XM_044310014.1 1571 0 0 1 0 P70490 3.64e-52 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 16560 XM_044310014.1 1571 0 0 1 0 P70490 4.12e-52 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 16561 XM_044310014.1 1571 0 0 1 0 P70490 3.27e-51 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 16562 XM_044310014.1 1571 0 0 1 0 P70490 3.43e-51 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 16563 XM_044310014.1 1571 0 0 1 0 P70490 9.84e-51 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 16564 XM_044310014.1 1571 0 0 1 0 P70490 2.52e-50 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 16565 XM_044310014.1 1571 0 0 1 0 P70490 3.05e-50 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 16566 XM_044310014.1 1571 0 0 1 0 P70490 5.98e-50 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 16567 XM_044310014.1 1571 0 0 1 0 P70490 6.15e-50 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 16568 XM_044310014.1 1571 0 0 1 0 P70490 8.91e-50 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 16569 XM_044310014.1 1571 0 0 1 0 P70490 1.4e-49 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 16570 XM_044310014.1 1571 0 0 1 0 P70490 1.85e-49 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 16571 XM_044310014.1 1571 0 0 1 0 P70490 2.81e-49 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 16572 XM_044310014.1 1571 0 0 1 0 P70490 2.97e-49 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 16573 XM_044310014.1 1571 0 0 1 0 P70490 6.72e-49 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 16574 XM_044310014.1 1571 0 0 1 0 P70490 7.97e-49 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 16575 XM_044310014.1 1571 0 0 1 0 P70490 1.29e-48 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 16576 XM_044310014.1 1571 0 0 1 0 P70490 3.6e-48 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 16577 XM_044310014.1 1571 0 0 1 0 P70490 1.12e-46 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 16578 XM_044309607.1 11 41 27 17 60 NA NA NA NA NA NA 16579 XR_003827483.2 111 55 81 53 188 NA NA NA NA NA NA 16580 XM_029325133.2 4781 8584 2446 4727 3434 Q9Y6P5 8.41e-138 Sestrin-1 (EC 1.11.1.-) (p53-regulated protein PA26) Homo sapiens (Human) cellular oxidant detoxification [GO:0098869]; cellular response to amino acid starvation [GO:0034198]; cellular response to glucose starvation [GO:0042149]; cellular response to leucine [GO:0071233]; cellular response to leucine starvation [GO:1990253]; negative regulation of TORC1 signaling [GO:1904262]; positive regulation of macroautophagy [GO:0016239]; reactive oxygen species metabolic process [GO:0072593]; regulation of response to reactive oxygen species [GO:1901031] GO:0001650; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0016239; GO:0016684; GO:0034198; GO:0042149; GO:0070728; GO:0071233; GO:0072593; GO:0098869; GO:1901031; GO:1904262; GO:1990253 16581 XM_029343966.2 1262 1105 49 96 192 Q9DE27 0 RuvB-like 2 (EC 3.6.4.12) (Reptin) Xenopus laevis (African clawed frog) DNA recombination [GO:0006310]; DNA repair [GO:0006281] GO:0000812; GO:0004386; GO:0005524; GO:0006281; GO:0006310; GO:0008094; GO:0016887; GO:0071339; GO:0120293 16582 XM_044306986.1 12 4 11 0 77 NA NA NA NA NA NA 16583 XM_044319811.1 15 29 43 17 142 Q2KHY5 2.24e-36 Fanconi anemia core complex-associated protein 24 (Fanconi anemia-associated protein of 24 kDa) Bos taurus (Bovine) interstrand cross-link repair [GO:0036297] GO:0000785; GO:0003677; GO:0003682; GO:0005654; GO:0036297; GO:0043240; GO:0071821 16584 XM_044327054.1 20 32 35 37 25 Q9NSA2 1.21e-63 Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) Homo sapiens (Human) potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005250; GO:0005886; GO:0008076; GO:0014069; GO:0016020; GO:0034765; GO:0043025; GO:0043197; GO:0045211; GO:0046872; GO:0051260; GO:0071805 16585 XM_044312497.1 550 86 14 209 185 Q92997 3.39e-146 Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; intracellular signal transduction [GO:0035556]; non-canonical Wnt signaling pathway [GO:0035567]; non-canonical Wnt signaling pathway via JNK cascade [GO:0038031]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of GTPase activity [GO:0043547]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein stabilization [GO:0050821]; regulation of protein localization [GO:0032880]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0000785; GO:0001934; GO:0002020; GO:0005102; GO:0005109; GO:0005829; GO:0008013; GO:0031267; GO:0032880; GO:0035556; GO:0035567; GO:0038031; GO:0043507; GO:0043547; GO:0045893; GO:0045944; GO:0050821; GO:0060070; GO:0060071; GO:0090179; GO:0150012 16586 XR_006395316.1 2863 1881 2282 2068 1774 NA NA NA NA NA NA 16587 XR_006395821.1 1 5 0 0 35 NA NA NA NA NA NA 16588 XM_044316613.1 293 242 207 384 539 NA NA NA NA NA NA 16589 XM_029333935.2 110 103 126 39 150 NA NA NA NA NA NA 16590 XR_003826296.2 121 42 35 9 139 NA NA NA NA NA NA 16591 XM_029333907.2 517 615 402 995 651 Q9Y519 1.32e-144 Transmembrane protein 184B (Putative MAPK-activating protein FM08) Homo sapiens (Human) NA GO:0016020 16592 XM_044320697.1 0 3 1 0 23 NA NA NA NA NA NA 16593 XR_003826881.2 0 165 21 49 0 Q96DB2 4.57e-126 Histone deacetylase 11 (HD11) (EC 3.5.1.98) Homo sapiens (Human) chromatin organization [GO:0006325]; histone deacetylation [GO:0016575]; oligodendrocyte development [GO:0014003] GO:0000118; GO:0004407; GO:0005634; GO:0005886; GO:0006325; GO:0014003; GO:0016575; GO:0140297 16594 XR_003828425.2 8 18 13 11 17 NA NA NA NA NA NA 16595 XM_029339820.2 652 320 246 543 657 Q96MD2 5.68e-127 KICSTOR subunit 2 (KICSTOR complex protein C12orf66) Homo sapiens (Human) cellular response to amino acid starvation [GO:0034198]; cellular response to glucose starvation [GO:0042149]; negative regulation of TORC1 signaling [GO:1904262]; protein localization to lysosome [GO:0061462] GO:0005764; GO:0005765; GO:0034198; GO:0042149; GO:0045171; GO:0061462; GO:0140007; GO:1904262 16596 XM_044309346.1 24 8 45 30 39 NA NA NA NA NA NA 16597 XM_044309365.1 1 0 0 2 6 NA NA NA NA NA NA 16598 XM_044325055.1 0 10 0 0 0 P27643 3.91e-36 Stage V sporulation protein K Bacillus subtilis (strain 168) sporulation resulting in formation of a cellular spore [GO:0030435] GO:0005524; GO:0016887; GO:0030435 16599 XM_044323356.1 127 47 95 69 132 Q5REV5 0 Acyl-coenzyme A synthetase ACSM3, mitochondrial (EC 6.2.1.2) (Acyl-CoA synthetase medium-chain family member 3) (Butyrate--CoA ligase 3) (Butyryl-coenzyme A synthetase 3) (Middle-chain acyl-CoA synthetase 3) (Propionate--CoA ligase) (EC 6.2.1.17) (Protein SA homolog) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) fatty acid biosynthetic process [GO:0006633] GO:0005524; GO:0005739; GO:0005759; GO:0006633; GO:0018729; GO:0043759; GO:0046872; GO:0047760; GO:0050218 16600 XM_044321860.1 41 241 100 227 0 Q8BMK0 8.5e-36 Centrosomal protein of 85 kDa (Cep85) (Coiled-coil domain-containing protein 21) Mus musculus (Mouse) chromosome segregation [GO:0007059]; negative regulation of protein kinase activity [GO:0006469]; neuron migration [GO:0001764]; regulation of mitotic centrosome separation [GO:0046602] GO:0000242; GO:0000922; GO:0001764; GO:0005730; GO:0005794; GO:0005813; GO:0005829; GO:0006469; GO:0007059; GO:0046602 16601 XR_006395374.1 119 40 50 87 141 NA NA NA NA NA NA 16602 XM_029341942.2 96 51 88 75 189 Q7ZVH1 5.77e-30 Membrane progestin receptor gamma-A (mPR gamma-A) (Progestin and adipoQ receptor family member V-A) Danio rerio (Zebrafish) (Brachydanio rerio) oogenesis [GO:0048477] GO:0005496; GO:0016020; GO:0038023; GO:0048477 16603 XM_029334384.2 4033 4484 948 5012 3716 Q96HN2 0 Adenosylhomocysteinase 3 (AdoHcyase 3) (EC 3.13.2.1) (IP(3)Rs binding protein released with IP(3) 2) (IRBIT2) (Long-IRBIT) (S-adenosyl-L-homocysteine hydrolase 3) (S-adenosylhomocysteine hydrolase-like protein 2) Homo sapiens (Human) one-carbon metabolic process [GO:0006730]; S-adenosylmethionine cycle [GO:0033353] GO:0005783; GO:0005829; GO:0006730; GO:0016787; GO:0033353; GO:0043005 16604 XM_044327118.1 103 11 100 99 363 P48416 7.43e-80 Cytochrome P450 10 (EC 1.14.-.-) (CYPX) Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004497; GO:0005506; GO:0016705; GO:0020037 16605 XR_003828215.2 34 11 11 1 20 NA NA NA NA NA NA 16606 XM_044320998.1 52 243 37 39 83 NA NA NA NA NA NA 16607 XM_029348017.2 4189 3152 3909 3091 2162 Q8TF32 2.09e-66 Zinc finger protein 431 Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355] GO:0000122; GO:0000978; GO:0000981; GO:0003682; GO:0005634; GO:0006355; GO:0030154; GO:0043433; GO:0046872 16608 XM_029348017.2 4189 3152 3909 3091 2162 Q8TF32 1.12e-63 Zinc finger protein 431 Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355] GO:0000122; GO:0000978; GO:0000981; GO:0003682; GO:0005634; GO:0006355; GO:0030154; GO:0043433; GO:0046872 16609 XM_029348017.2 4189 3152 3909 3091 2162 Q8TF32 1.66e-62 Zinc finger protein 431 Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355] GO:0000122; GO:0000978; GO:0000981; GO:0003682; GO:0005634; GO:0006355; GO:0030154; GO:0043433; GO:0046872 16610 XM_029348017.2 4189 3152 3909 3091 2162 Q8TF32 1.55e-60 Zinc finger protein 431 Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355] GO:0000122; GO:0000978; GO:0000981; GO:0003682; GO:0005634; GO:0006355; GO:0030154; GO:0043433; GO:0046872 16611 XM_029348017.2 4189 3152 3909 3091 2162 Q8TF32 8.84e-56 Zinc finger protein 431 Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355] GO:0000122; GO:0000978; GO:0000981; GO:0003682; GO:0005634; GO:0006355; GO:0030154; GO:0043433; GO:0046872 16612 XM_029348017.2 4189 3152 3909 3091 2162 Q8TF32 1.09e-49 Zinc finger protein 431 Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355] GO:0000122; GO:0000978; GO:0000981; GO:0003682; GO:0005634; GO:0006355; GO:0030154; GO:0043433; GO:0046872 16613 XM_029348017.2 4189 3152 3909 3091 2162 Q8TF32 4.27e-40 Zinc finger protein 431 Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355] GO:0000122; GO:0000978; GO:0000981; GO:0003682; GO:0005634; GO:0006355; GO:0030154; GO:0043433; GO:0046872 16614 XM_029348017.2 4189 3152 3909 3091 2162 Q8TF32 6.25e-35 Zinc finger protein 431 Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355] GO:0000122; GO:0000978; GO:0000981; GO:0003682; GO:0005634; GO:0006355; GO:0030154; GO:0043433; GO:0046872 16615 XM_029348017.2 4189 3152 3909 3091 2162 Q8TF32 1.79e-28 Zinc finger protein 431 Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355] GO:0000122; GO:0000978; GO:0000981; GO:0003682; GO:0005634; GO:0006355; GO:0030154; GO:0043433; GO:0046872 16616 XM_044321875.1 0 0 0 1 42 Q93Z30 5.95e-27 NA NA NA NA 16617 XM_029334431.2 3 0 20 13 3 NA NA NA NA NA NA 16618 XM_044319861.1 658 138 399 403 495 NA NA NA NA NA NA 16619 XM_044316678.1 1215 1285 985 1543 1583 A6H5Z3 0 Exocyst complex component 6B (Exocyst complex component Sec15B) (SEC15-like protein 2) Mus musculus (Mouse) exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; intracellular protein transport [GO:0006886]; membrane fission [GO:0090148]; mitotic cytokinesis [GO:0000281]; vesicle docking involved in exocytosis [GO:0006904]; vesicle tethering involved in exocytosis [GO:0090522] GO:0000145; GO:0000281; GO:0006886; GO:0006887; GO:0006893; GO:0006904; GO:0090148; GO:0090522 16620 XR_006392156.1 268 27 160 357 641 NA NA NA NA NA NA 16621 XR_006391858.1 8 0 3 13 0 NA NA NA NA NA NA 16622 XR_006396411.1 0 0 20 0 50 NA NA NA NA NA NA 16623 XM_044315096.1 35 0 64 55 0 NA NA NA NA NA NA 16624 XM_029329072.2 10287 9194 6165 8288 7797 P41240 7.55e-168 Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase CYL) Homo sapiens (Human) adaptive immune response [GO:0002250]; adherens junction organization [GO:0034332]; brain development [GO:0007420]; cellular response to peptide hormone stimulus [GO:0071375]; negative regulation of bone resorption [GO:0045779]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of Golgi to plasma membrane protein transport [GO:0042997]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of kinase activity [GO:0033673]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of phagocytosis [GO:0050765]; oligodendrocyte differentiation [GO:0048709]; positive regulation of MAP kinase activity [GO:0043406]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of Fc receptor mediated stimulatory signaling pathway [GO:0060368]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852] GO:0002250; GO:0004713; GO:0004715; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0005911; GO:0006468; GO:0007420; GO:0008022; GO:0008285; GO:0010989; GO:0019903; GO:0031295; GO:0032715; GO:0033673; GO:0034236; GO:0034332; GO:0042802; GO:0042997; GO:0043406; GO:0045121; GO:0045779; GO:0046777; GO:0046872; GO:0048709; GO:0050765; GO:0050852; GO:0060368; GO:0070062; GO:0070064; GO:0070373; GO:0071375; GO:1990782 16625 XR_006396539.1 15 2 8 0 0 NA NA NA NA NA NA 16626 XM_029353579.2 477 315 139 509 511 P22083 1.83e-42 Alpha-(1,3)-fucosyltransferase 4 (4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase) (EC 2.4.1.152) (ELAM-1 ligand fucosyltransferase) (Fucosyltransferase 4) (Fucosyltransferase IV) (Fuc-TIV) (FucT-IV) (Galactoside 3-L-fucosyltransferase) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; fucosylation [GO:0036065]; glycosphingolipid biosynthetic process [GO:0006688]; inflammatory response [GO:0006954]; L-fucose catabolic process [GO:0042355]; lymphocyte migration into lymph node [GO:0097022]; oligosaccharide biosynthetic process [GO:0009312]; oligosaccharide metabolic process [GO:0009311]; positive regulation of leukocyte tethering or rolling [GO:1903238]; positive regulation of neutrophil migration [GO:1902624]; protein glycosylation [GO:0006486]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493]; regulation of leukocyte cell-cell adhesion [GO:1903037] GO:0000139; GO:0005794; GO:0005802; GO:0005975; GO:0006486; GO:0006487; GO:0006493; GO:0006688; GO:0006954; GO:0008417; GO:0009311; GO:0009312; GO:0009986; GO:0016020; GO:0017083; GO:0032580; GO:0036065; GO:0042355; GO:0046920; GO:0071944; GO:0097022; GO:1902624; GO:1903037; GO:1903238 16627 XR_003824981.2 589 544 337 406 461 NA NA NA NA NA NA 16628 XM_029343564.2 1351 1043 916 1523 1560 NA NA NA NA NA NA 16629 XM_029329456.2 100 0 40 54 536 Q13823 0 Nucleolar GTP-binding protein 2 (Autoantigen NGP-1) Homo sapiens (Human) ribosome biogenesis [GO:0042254] GO:0003723; GO:0003924; GO:0005525; GO:0005634; GO:0005730; GO:0016020; GO:0042254 16630 XR_006394138.1 41 2 25 5 151 NA NA NA NA NA NA 16631 XM_044323272.1 412 71 346 597 1116 NA NA NA NA NA NA 16632 XM_029357268.2 89 169 127 258 262 NA NA NA NA NA NA 16633 XR_006395293.1 79 53 34 15 34 Q9UHC6 6e-80 Contactin-associated protein-like 2 (Cell recognition molecule Caspr2) Homo sapiens (Human) adult behavior [GO:0030534]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell population proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; clustering of voltage-gated potassium channels [GO:0045163]; learning [GO:0007612]; limbic system development [GO:0021761]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuron recognition [GO:0008038]; positive regulation of gap junction assembly [GO:1903598]; protein localization to juxtaparanode region of axon [GO:0071205]; social behavior [GO:0035176]; striatum development [GO:0021756]; superior temporal gyrus development [GO:0071109]; thalamus development [GO:0021794]; transmission of nerve impulse [GO:0019226]; vocal learning [GO:0042297]; vocalization behavior [GO:0071625] GO:0005769; GO:0005794; GO:0007155; GO:0007420; GO:0007612; GO:0008038; GO:0008076; GO:0008283; GO:0009986; GO:0016020; GO:0019226; GO:0019899; GO:0021756; GO:0021761; GO:0021794; GO:0021987; GO:0030424; GO:0030425; GO:0030534; GO:0030673; GO:0031175; GO:0033010; GO:0035176; GO:0042297; GO:0043025; GO:0043204; GO:0044224; GO:0045163; GO:0048812; GO:0071109; GO:0071205; GO:0071625; GO:1903598 16634 XM_029342608.2 317 56 258 954 653 Q9VBW3 4.35e-85 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 16635 XM_044315506.1 1 1 9 0 7 NA NA NA NA NA NA 16636 XM_044309258.1 2 4 64 85 43 NA NA NA NA NA NA 16637 XM_029335058.2 128 74 45 108 164 Q4R7I0 1.13e-26 Centrosomal protein of 44 kDa (Cep44) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) centriole replication [GO:0007099]; centriole-centriole cohesion [GO:0010457]; centrosome cycle [GO:0007098] GO:0000922; GO:0005737; GO:0005813; GO:0005814; GO:0007098; GO:0007099; GO:0008017; GO:0010457; GO:0030496 16638 XR_006397846.1 62 0 0 0 126 NA NA NA NA NA NA 16639 XM_044312236.1 2 0 7 4 10 NA NA NA NA NA NA 16640 XM_029349895.2 2185 1300 1003 2276 1467 Q6S5C2 3.7e-61 N-acetylglucosamine-1-phosphotransferase subunit gamma (GlcNAc-1-phosphotransferase subunit gamma) (M6PR domain-containing protein 1) (UDP-N-acetylglucosamine-1-phosphotransferase subunit gamma) Mus musculus (Mouse) carbohydrate phosphorylation [GO:0046835] GO:0000139; GO:0003976; GO:0005576; GO:0005794; GO:0016020; GO:0042803; GO:0043231; GO:0046835; GO:0070622 16641 XM_044308004.1 4 4 3 14 24 NA NA NA NA NA NA 16642 XM_044314032.1 134 185 56 120 182 NA NA NA NA NA NA 16643 XM_044323310.1 98 26 23 22 63 P16157 9.99e-78 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 16644 XM_044323310.1 98 26 23 22 63 P16157 1.01e-61 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 16645 XM_044323310.1 98 26 23 22 63 P16157 4.01e-57 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 16646 XM_044323310.1 98 26 23 22 63 P16157 1.78e-51 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 16647 XM_044323310.1 98 26 23 22 63 P16157 1.44e-45 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 16648 XM_044325528.1 392 182 142 201 371 NA NA NA NA NA NA 16649 XM_029351480.2 49 23 21 53 21 Q2YDN1 2.19e-29 G protein-coupled receptor 161 Bos taurus (Bovine) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:1901621] GO:0004930; GO:0005929; GO:0007186; GO:0007189; GO:0055037; GO:0060170; GO:1901621 16650 XM_044327491.1 594 243 444 392 91 NA NA NA NA NA NA 16651 XM_044308388.1 570 466 563 334 117 Q8IVB4 0 Sodium/hydrogen exchanger 9 (Na(+)/H(+) exchanger 9) (NHE-9) (Solute carrier family 9 member 9) Homo sapiens (Human) defense response to bacterium [GO:0042742]; ion transport [GO:0006811]; phagosome maturation [GO:0090382]; potassium ion transmembrane transport [GO:0071805]; regulation of intracellular pH [GO:0051453]; sodium ion import across plasma membrane [GO:0098719] GO:0005769; GO:0005886; GO:0006811; GO:0015385; GO:0015386; GO:0030670; GO:0031902; GO:0032009; GO:0042742; GO:0051453; GO:0055037; GO:0055038; GO:0071805; GO:0090382; GO:0098719 16652 XM_044323157.1 1 0 7 8 0 Q96NI8 2.93e-64 Zinc finger protein 570 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 16653 XM_044323157.1 1 0 7 8 0 Q96NI8 9.41e-63 Zinc finger protein 570 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 16654 XM_044323157.1 1 0 7 8 0 Q96NI8 8.01e-60 Zinc finger protein 570 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 16655 XM_044323157.1 1 0 7 8 0 Q96NI8 5.5e-58 Zinc finger protein 570 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 16656 XM_044323157.1 1 0 7 8 0 Q96NI8 9.29e-56 Zinc finger protein 570 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 16657 XM_044323157.1 1 0 7 8 0 Q96NI8 6.48e-50 Zinc finger protein 570 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 16658 XM_044323157.1 1 0 7 8 0 Q96NI8 3.63e-37 Zinc finger protein 570 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 16659 XM_029355948.2 401 0 75 62 358 Q26626 0 Kinesin-associated protein 3 (SpKAP115) Strongylocentrotus purpuratus (Purple sea urchin) cilium organization [GO:0044782]; microtubule-based movement [GO:0007018]; microtubule-based process [GO:0007017] GO:0005930; GO:0007017; GO:0007018; GO:0016939; GO:0019894; GO:0035869; GO:0044782 16660 XM_029347084.2 0 204 73 91 209 Q6P6X9 2.25e-69 Nucleoporin NUP35 (35 kDa nucleoporin) (Nuclear pore complex protein Nup53) (Nucleoporin NUP53) Danio rerio (Zebrafish) (Brachydanio rerio) mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; nuclear pore organization [GO:0006999] GO:0003676; GO:0005543; GO:0006607; GO:0006999; GO:0017056; GO:0031965; GO:0044613; GO:0044615; GO:0051028 16661 XM_044310880.1 13 4 18 22 18 NA NA NA NA NA NA 16662 XM_029338814.2 1648 1517 989 1198 851 Q5R8R4 2.16e-175 CWF19-like protein 1 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA NA 16663 XM_044321611.1 183 32 43 11 82 E9Q5R7 4.95e-48 NACHT, LRR and PYD domains-containing protein 12 (Monarch-1) (PYRIN-containing APAF1-like protein 7) (PYPAF7) Mus musculus (Mouse) cellular response to cytokine stimulus [GO:0071345]; dendritic cell migration [GO:0036336]; ERK1 and ERK2 cascade [GO:0070371]; negative regulation of cytokine production [GO:0001818]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of signal transduction [GO:0009968]; negative regulation of Toll signaling pathway [GO:0045751]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of inflammatory response [GO:0050727] GO:0001818; GO:0005524; GO:0005737; GO:0009968; GO:0031953; GO:0032088; GO:0032692; GO:0032715; GO:0036336; GO:0038061; GO:0043122; GO:0043124; GO:0043281; GO:0045345; GO:0045751; GO:0050727; GO:0050728; GO:0070371; GO:0070373; GO:0071345; GO:1901223; GO:1901224 16664 XR_006394300.1 2 0 1 1 33 NA NA NA NA NA NA 16665 XM_044326326.1 38 21 17 26 43 NA NA NA NA NA NA 16666 XM_029349310.2 0 0 0 28 0 NA NA NA NA NA NA 16667 XM_029338541.2 0 0 0 14 43 NA NA NA NA NA NA 16668 XM_044313220.1 120 67 139 171 171 Q9JME2 6.54e-49 Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4S-1) (C4ST-1) (C4ST1) Mus musculus (Mouse) apoptotic process [GO:0006915]; carbohydrate biosynthetic process [GO:0016051]; cartilage development [GO:0051216]; chondrocyte development [GO:0002063]; chondroitin sulfate biosynthetic process [GO:0030206]; chondroitin sulfate metabolic process [GO:0030204]; developmental growth [GO:0048589]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; embryonic viscerocranium morphogenesis [GO:0048703]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; polysaccharide localization [GO:0033037]; post-anal tail morphogenesis [GO:0036342]; post-embryonic development [GO:0009791]; proteoglycan biosynthetic process [GO:0030166]; regulation of cell population proliferation [GO:0042127]; respiratory gaseous exchange by respiratory system [GO:0007585]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0000139; GO:0001537; GO:0001701; GO:0002063; GO:0006915; GO:0007179; GO:0007585; GO:0008146; GO:0009791; GO:0016051; GO:0030166; GO:0030204; GO:0030206; GO:0030326; GO:0030512; GO:0033037; GO:0036342; GO:0042127; GO:0042733; GO:0043066; GO:0047756; GO:0048589; GO:0048703; GO:0048704; GO:0050659; GO:0051216 16669 XM_029324763.2 0 0 0 0 10 Q14246 2.86e-24 Adhesion G protein-coupled receptor E1 (EGF-like module receptor 1) (EGF-like module-containing mucin-like hormone receptor-like 1) (EMR1 hormone receptor) Homo sapiens (Human) adaptive immune response [GO:0002250]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0002250; GO:0004930; GO:0005509; GO:0005886; GO:0007155; GO:0007166; GO:0007186; GO:0007189; GO:0009897 16670 XM_029324763.2 0 0 0 0 10 Q14246 5.82e-21 Adhesion G protein-coupled receptor E1 (EGF-like module receptor 1) (EGF-like module-containing mucin-like hormone receptor-like 1) (EMR1 hormone receptor) Homo sapiens (Human) adaptive immune response [GO:0002250]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0002250; GO:0004930; GO:0005509; GO:0005886; GO:0007155; GO:0007166; GO:0007186; GO:0007189; GO:0009897 16671 XM_029338198.2 7421 8157 6832 8703 6227 Q96C19 4.48e-53 EF-hand domain-containing protein D2 (Swiprosin-1) Homo sapiens (Human) NA GO:0005509; GO:0045121; GO:0045296 16672 XR_006396041.1 327 222 41 15 62 NA NA NA NA NA NA 16673 XM_044306852.1 212 373 434 688 416 NA NA NA NA NA NA 16674 XM_044315538.1 1749 110 1757 343 9979 NA NA NA NA NA NA 16675 XR_006396293.1 10 84 59 133 97 NA NA NA NA NA NA 16676 XM_029336126.2 2372 1329 2017 2317 2335 Q8BHL3 4.29e-115 TBC1 domain family member 10B (Protein wz3-85) Mus musculus (Mouse) activation of GTPase activity [GO:0090630]; regulation of GTPase activity [GO:0043087]; retrograde transport, endosome to Golgi [GO:0042147] GO:0005096; GO:0005829; GO:0005886; GO:0042147; GO:0043087; GO:0090630 16677 XM_029346815.2 37 4 17 95 24 NA NA NA NA NA NA 16678 XM_044318512.1 328 255 171 169 243 B2RYF1 1.01e-136 Protein phosphatase 1 regulatory subunit 37 (Leucine-rich repeat-containing protein 68) Rattus norvegicus (Rat) NA GO:0004864 16679 XM_044315836.1 204 20 6 30 192 Q99315 4.17e-92 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 16680 XM_029333650.2 294 305 166 282 215 Q1T7B7 1.19e-23 Centromere protein P (CENP-P) Gallus gallus (Chicken) CENP-A containing chromatin assembly [GO:0034080] GO:0000775; GO:0005634; GO:0034080 16681 XR_006393934.1 1069 948 11524 1041 1492 NA NA NA NA NA NA 16682 XM_044325574.1 0 0 24 0 0 NA NA NA NA NA NA 16683 XM_029331924.2 2671 3259 1937 3896 3130 Q58D84 6.21e-69 Follistatin-related protein 1 (Follistatin-like protein 1) Bos taurus (Bovine) cell differentiation [GO:0030154]; endothelial cell differentiation [GO:0045446]; endothelial cell migration [GO:0043542]; negative regulation of apoptotic process [GO:0043066]; regulation of BMP signaling pathway [GO:0030510] GO:0005509; GO:0005576; GO:0008201; GO:0030154; GO:0030510; GO:0043066; GO:0043542; GO:0045446 16684 XM_029349189.2 10 0 4 5 20 NA NA NA NA NA NA 16685 XM_044322898.1 0 1 18 0 220 NA NA NA NA NA NA 16686 XM_029327714.2 8 5 0 0 0 NA NA NA NA NA NA 16687 XM_044325641.1 0 25 10 7 22 NA NA NA NA NA NA 16688 XM_029333374.2 2129 5273 227 3274 1850 NA NA NA NA NA NA 16689 XM_044315110.1 7 2 5 0 0 NA NA NA NA NA NA 16690 XM_029356578.2 1274 827 513 892 481 Q08CH8 3.49e-116 Zinc finger TRAF-type-containing protein 1 (Cysteine and histidine-rich protein 1) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0046872; GO:0048471 16691 XR_003824261.2 5 2 7 5 3 NA NA NA NA NA NA 16692 XM_044314455.1 133 2708 3362 175 4766 P34334 1.6e-51 60S ribosomal protein L21 Caenorhabditis elegans translation [GO:0006412] GO:0003735; GO:0006412; GO:0022625 16693 XM_044311169.1 178 295 299 72 695 Q9M2U3 2.74e-30 Protein ALP1-like (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) NA GO:0000118; GO:0004518; GO:0046872 16694 XM_044316923.1 2514 1659 913 2199 2090 Q01617 2.89e-38 Protein couch potato Drosophila melanogaster (Fruit fly) chemical synaptic transmission [GO:0007268]; dormancy process [GO:0022611]; regulation of hemocyte proliferation [GO:0035206] GO:0003729; GO:0005634; GO:0007268; GO:0022611; GO:0035206; GO:0045202 16695 XM_029334154.2 94 58 45 119 86 Q96Q27 5.55e-63 Ankyrin repeat and SOCS box protein 2 (ASB-2) Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; cardiac muscle cell development [GO:0055013]; cardiac muscle cell differentiation [GO:0055007]; dendritic cell migration [GO:0036336]; heart looping [GO:0001947]; intracellular signal transduction [GO:0035556]; podosome assembly [GO:0071800]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; signal transduction [GO:0007165]; skeletal muscle atrophy [GO:0014732]; skeletal muscle cell differentiation [GO:0035914]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000151; GO:0001947; GO:0005829; GO:0005856; GO:0006511; GO:0007165; GO:0014732; GO:0016567; GO:0030018; GO:0031532; GO:0035556; GO:0035914; GO:0036336; GO:0043161; GO:0055007; GO:0055013; GO:0071800; GO:0097602 16696 XM_044318952.1 11 10 18 28 27 Q2S1V4 1.2e-164 Tryptophanase (EC 4.1.99.1) (L-tryptophan indole-lyase) (TNase) Salinibacter ruber (strain DSM 13855 / M31) NA GO:0009034 16697 XM_029347839.2 172 62 28 0 350 Q6GM44 1e-116 E3 ubiquitin-protein ligase MARCHF5 (EC 2.3.2.27) (Membrane-associated RING finger protein 5) (Membrane-associated RING-CH protein V) (MARCH-V) (RING-type E3 ubiquitin transferase MARCHF5) Xenopus laevis (African clawed frog) protein autoubiquitination [GO:0051865]; regulation of mitochondrial fission [GO:0090140] GO:0005741; GO:0005783; GO:0005789; GO:0008270; GO:0051865; GO:0061630; GO:0090140 16698 XM_044325737.1 449 310 274 387 393 Q95K09 1.06e-109 Gamma-tubulin complex component 5 (GCP-5) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) microtubule nucleation [GO:0007020] GO:0000922; GO:0000931; GO:0005813; GO:0005829; GO:0005874; GO:0007020; GO:0008017; GO:0043015 16699 XM_029350376.2 0 0 6 0 0 Q24488 1.83e-82 Tyrosine-protein kinase transmembrane receptor Ror (dRor) (EC 2.7.10.1) Drosophila melanogaster (Fruit fly) central nervous system development [GO:0007417]; positive regulation of kinase activity [GO:0033674]; positive regulation of neuron projection development [GO:0010976]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0004713; GO:0004714; GO:0005524; GO:0005886; GO:0006468; GO:0007169; GO:0007417; GO:0010976; GO:0014068; GO:0016020; GO:0017147; GO:0033674; GO:0043235 16700 XM_044310411.1 1 183 3 22 201 NA NA NA NA NA NA 16701 XR_006396746.1 45 27 21 3 34 NA NA NA NA NA NA 16702 XM_029345877.2 0 22 0 0 22 Q9I9K7 2.2e-116 T-box transcription factor TBX20 (T-box protein 20) (H15-related T-box transcription factor hrT) Danio rerio (Zebrafish) (Brachydanio rerio) angiogenesis [GO:0001525]; blood vessel development [GO:0001568]; cardiac muscle cell proliferation [GO:0060038]; cell fate specification [GO:0001708]; cloaca development [GO:0035844]; embryonic heart tube development [GO:0035050]; embryonic hemopoiesis [GO:0035162]; heart development [GO:0007507]; heart looping [GO:0001947]; heart rudiment development [GO:0003313]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of transcription by RNA polymerase II [GO:0006357]; vasculogenesis [GO:0001570] GO:0000978; GO:0000981; GO:0001525; GO:0001568; GO:0001570; GO:0001708; GO:0001947; GO:0003313; GO:0005634; GO:0006357; GO:0007507; GO:0035050; GO:0035162; GO:0035844; GO:0045892; GO:0045893; GO:0060038; GO:0060043 16703 XM_044329303.1 15 0 25 0 15 Q9BQP7 7.48e-38 Mitochondrial genome maintenance exonuclease 1 (EC 3.1.-.-) Homo sapiens (Human) mitochondrial DNA repair [GO:0043504]; mitochondrial DNA replication [GO:0006264]; mitochondrial genome maintenance [GO:0000002] GO:0000002; GO:0005739; GO:0006264; GO:0008297; GO:0043504 16704 XM_044321486.1 0 1037 42 0 0 Q01804 1.65e-71 OTU domain-containing protein 4 (EC 3.4.19.12) (HIV-1-induced protein HIN-1) Homo sapiens (Human) innate immune response [GO:0045087]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; positive regulation of DNA demethylation [GO:1901537]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; regulation of protein K48-linked deubiquitination [GO:1903093] GO:0003723; GO:0004843; GO:0005634; GO:0005829; GO:0016579; GO:0034122; GO:0045087; GO:0060090; GO:0061578; GO:0070536; GO:0071108; GO:1901537; GO:1903093; GO:2000660 16705 XM_044318730.1 167 64 16 153 33 Q8BFR2 1.65e-56 Follistatin-related protein 5 (Follistatin-like protein 5) (m-D/Bsp120I 1-2) Mus musculus (Mouse) cell differentiation [GO:0030154] GO:0005509; GO:0005576; GO:0030154 16706 XM_044318730.1 167 64 16 153 33 Q8BFR2 2.78e-22 Follistatin-related protein 5 (Follistatin-like protein 5) (m-D/Bsp120I 1-2) Mus musculus (Mouse) cell differentiation [GO:0030154] GO:0005509; GO:0005576; GO:0030154 16707 XM_029333214.2 69 82 43 125 217 NA NA NA NA NA NA 16708 XR_006396447.1 3 0 8 20 21 O60290 7.89e-27 Zinc finger protein 862 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006355; GO:0046872; GO:0046983 16709 XR_006397346.1 9 0 8 12 0 NA NA NA NA NA NA 16710 XM_029347231.2 1510 1552 878 1566 1532 Q9VT65 2.37e-173 Calpain-B (EC 3.4.22.-) (Calcium-activated neutral proteinase B) (CANP B) [Cleaved into: Calpain-B catalytic subunit 1; Calpain-B catalytic subunit 2] Drosophila melanogaster (Fruit fly) border follicle cell migration [GO:0007298]; neuron remodeling [GO:0016322]; protein autoprocessing [GO:0016540]; proteolysis [GO:0006508] GO:0004198; GO:0005509; GO:0005737; GO:0006508; GO:0007298; GO:0016020; GO:0016322; GO:0016540 16711 XM_029352956.2 2243 2400 2545 2254 2669 Q803Z2 2.27e-71 Protein YIPF3 (YIP1 family member 3) Danio rerio (Zebrafish) (Brachydanio rerio) cell differentiation [GO:0030154] GO:0005794; GO:0005886; GO:0030154 16712 XM_029352442.2 214 85 100 154 313 Q9Y672 4.87e-123 Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase (EC 2.4.1.267) (Asparagine-linked glycosylation protein 6 homolog) (Dol-P-Glc:Man(9)GlcNAc(2)-PP-Dol alpha-1,3-glucosyltransferase) (Dolichyl-P-Glc:Man9GlcNAc2-PP-dolichyl glucosyltransferase) Homo sapiens (Human) dolichol-linked oligosaccharide biosynthetic process [GO:0006488]; oligosaccharide-lipid intermediate biosynthetic process [GO:0006490]; protein N-linked glycosylation [GO:0006487] GO:0004583; GO:0005789; GO:0006487; GO:0006488; GO:0006490; GO:0016020; GO:0042281; GO:0046527 16713 XM_044313539.1 6 3 0 2 46 NA NA NA NA NA NA 16714 XM_044317586.1 3 3 2 13 50 NA NA NA NA NA NA 16715 XR_003826025.1 1 0 11 6 1 NA NA NA NA NA NA 16716 XM_044319220.1 11 13 22 19 35 O62852 3.22e-92 Short transient receptor potential channel 5 (Rtrp5) (TrpC5) (Capacitative calcium entry channel 2) (CCE2) Oryctolagus cuniculus (Rabbit) neuron apoptotic process [GO:0051402]; phosphatidylserine exposure on apoptotic cell surface [GO:0070782] GO:0005262; GO:0005886; GO:0034704; GO:0051402; GO:0070679; GO:0070782 16717 XR_006394852.1 15 20 65 50 33 NA NA NA NA NA NA 16718 XM_044323556.1 7 98 17 3 1 NA NA NA NA NA NA 16719 XM_029345789.2 225 0 112 8 131 NA NA NA NA NA NA 16720 XM_029332066.2 564 467 189 497 464 NA NA NA NA NA NA 16721 XM_044310206.1 0 1 0 20 13 NA NA NA NA NA NA 16722 XR_006393195.1 81 7 0 8 26 NA NA NA NA NA NA 16723 XM_029332368.2 2118 1408 906 1714 1877 F1QXM5 0 Probable D-lactate dehydrogenase, mitochondrial (DLD) (Lactate dehydrogenase D) (EC 1.1.2.4) Danio rerio (Zebrafish) (Brachydanio rerio) lactate catabolic process [GO:1903457] GO:0004458; GO:0005739; GO:0008720; GO:0050660; GO:0071949; GO:1903457 16724 XM_029324842.2 28 24 26 20 269 NA NA NA NA NA NA 16725 XM_029347116.2 0 13 2 5 7 NA NA NA NA NA NA 16726 XR_006395484.1 51 99 23 28 31 NA NA NA NA NA NA 16727 XM_044317682.1 395 339 297 221 296 NA NA NA NA NA NA 16728 XM_044326070.1 8261 6636 6918 3763 7966 P23574 2.15e-36 Gamma-aminobutyric acid receptor subunit gamma-1 (GABA(A) receptor subunit gamma-1) Rattus norvegicus (Rat) chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid signaling pathway [GO:0007214]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; regulation of postsynaptic membrane potential [GO:0060078]; signal transduction [GO:0007165]; synaptic transmission, GABAergic [GO:0051932] GO:0004890; GO:0005231; GO:0005237; GO:0005886; GO:0007165; GO:0007214; GO:0007268; GO:0016020; GO:0022851; GO:0030594; GO:0032590; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0043235; GO:0045202; GO:0045211; GO:0050811; GO:0050877; GO:0051932; GO:0060078; GO:0098794; GO:1902476; GO:1902711; GO:1904315 16729 XM_044316326.1 0 8 0 0 0 P51144 7.35e-41 Substance-K receptor (SKR) (NK-2 receptor) (NK-2R) (Neurokinin A receptor) (Tachykinin receptor 2) Mesocricetus auratus (Golden hamster) positive regulation of flagellated sperm motility [GO:1902093]; regulation of uterine smooth muscle contraction [GO:0070472] GO:0004995; GO:0005886; GO:0061827; GO:0070472; GO:0097225; GO:1902093 16730 XR_006394344.1 15 0 4 5 18 NA NA NA NA NA NA 16731 XM_044321907.1 2 1 7 8 17 NA NA NA NA NA NA 16732 XM_029332276.2 57 59 49 0 0 Q6NRS2 4.12e-95 Solute carrier family 66 member 2 (PQ-loop repeat-containing protein 1) Xenopus laevis (African clawed frog) NA GO:0016020 16733 XM_044318072.1 23 0 2 0 0 NA NA NA NA NA NA 16734 XM_029347249.2 158 244 94 162 77 NA NA NA NA NA NA 16735 XM_044324050.1 73 36 69 75 172 NA NA NA NA NA NA 16736 XM_029348709.2 2419 1371 1361 1742 1491 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16737 XM_029355237.2 3958 2738 1844 3100 3143 Q6DCZ9 3.29e-93 NEDD8-conjugating enzyme Ubc12 (EC 2.3.2.34) (NEDD8 carrier protein) (Ubiquitin-conjugating enzyme E2 M) Xenopus laevis (African clawed frog) protein modification process [GO:0036211]; protein neddylation [GO:0045116] GO:0004842; GO:0005524; GO:0019788; GO:0036211; GO:0045116; GO:0061654 16738 XM_044328066.1 128 28 23 149 127 P51892 0 DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1) Xenopus laevis (African clawed frog) cell cycle [GO:0007049]; cell division [GO:0051301]; DNA biosynthetic process [GO:0071897]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260] GO:0003677; GO:0003910; GO:0005524; GO:0005634; GO:0006260; GO:0006281; GO:0006310; GO:0007049; GO:0046872; GO:0051301; GO:0071897 16739 XM_044326491.1 14 0 14 3 15 NA NA NA NA NA NA 16740 XR_006395006.1 1 3 12 21 25 NA NA NA NA NA NA 16741 XM_029348859.2 200 198 252 119 133 O75081 4.78e-131 Protein CBFA2T3 (MTG8-related protein 2) (Myeloid translocation gene on chromosome 16 protein) (hMTG16) (Zinc finger MYND domain-containing protein 4) Homo sapiens (Human) granulocyte differentiation [GO:0030851]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of glycolytic process [GO:0045820]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; regulation of aerobic respiration [GO:1903715]; response to hypoxia [GO:0001666] GO:0000139; GO:0001666; GO:0003714; GO:0005634; GO:0005654; GO:0005730; GO:0008285; GO:0030851; GO:0032436; GO:0045820; GO:0045892; GO:0046872; GO:1903715 16742 XM_044316212.1 59 104 77 51 114 NA NA NA NA NA NA 16743 XM_044315833.1 420 506 398 429 611 NA NA NA NA NA NA 16744 XM_029327629.2 13 0 0 0 8 Q9M2U3 3.17e-26 Protein ALP1-like (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) NA GO:0000118; GO:0004518; GO:0046872 16745 XM_044321318.1 137 45 106 83 308 P46023 1.18e-102 G-protein coupled receptor GRL101 Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004930; GO:0005886 16746 XM_044321768.1 2450 1891 1205 2522 1973 A7T1N0 0 Transient receptor potential cation channel subfamily M member-like 2 (nvTRPM2) Nematostella vectensis (Starlet sea anemone) calcium ion transmembrane transport [GO:0070588]; cation transmembrane transport [GO:0098655]; sodium ion transmembrane transport [GO:0035725] GO:0005261; GO:0005886; GO:0015280; GO:0035725; GO:0046872; GO:0047631; GO:0070588; GO:0098655; GO:0099604 16747 XM_029337704.2 46 0 36 0 64 Q9GRC0 3e-76 Serine/threonine-protein kinase mos (EC 2.7.11.1) (Oocyte maturation factor mos) Patiria pectinifera (Starfish) (Asterina pectinifera) female gamete generation [GO:0007292]; female meiosis II [GO:0007147]; negative regulation of mitotic cell cycle [GO:0045930]; protein phosphorylation [GO:0006468] GO:0004709; GO:0005524; GO:0006468; GO:0007147; GO:0007292; GO:0045930; GO:0106310 16748 XM_029351259.2 9407 6513 4568 9834 9026 Q8VDJ3 0 Vigilin (High density lipoprotein-binding protein) (HDL-binding protein) Mus musculus (Mouse) cholesterol metabolic process [GO:0008203]; lipid transport [GO:0006869] GO:0003729; GO:0005634; GO:0005737; GO:0005829; GO:0005844; GO:0006869; GO:0008203; GO:0034364 16749 XM_044316773.1 13 3 8 3 135 NA NA NA NA NA NA 16750 XR_006393113.1 100 27 41 55 238 NA NA NA NA NA NA 16751 XM_044311371.1 28 42 21 52 35 C3VPR6 3.18e-26 Protein NLRC5 Mus musculus (Mouse) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of type II interferon-mediated signaling pathway [GO:0060335]; regulation of kinase activity [GO:0043549]; response to bacterium [GO:0009617] GO:0000978; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0009617; GO:0032088; GO:0035556; GO:0043549; GO:0045087; GO:0045345; GO:0045944; GO:0051607; GO:0060335; GO:0060339; GO:0060340 16752 XM_029339382.2 55392 65590 65241 139829 77571 NA NA NA NA NA NA 16753 XM_029342300.2 859 383 0 0 847 Q5F364 0 Multidrug resistance-associated protein 1 (EC 7.6.2.2) (ATP-binding cassette sub-family C member 1) (Glutathione-S-conjugate-translocating ATPase ABCC1) (EC 7.6.2.3) (Leukotriene C(4) transporter) (LTC4 transporter) Gallus gallus (Chicken) glutathione transmembrane transport [GO:0034775]; lipid transport [GO:0006869]; transmembrane transport [GO:0055085]; xenobiotic transport [GO:0042908] GO:0005524; GO:0006869; GO:0008559; GO:0016020; GO:0016323; GO:0016887; GO:0034634; GO:0034775; GO:0042626; GO:0042908; GO:0055085 16754 XM_044313927.1 415 291 93 0 25 NA NA NA NA NA NA 16755 XM_044321995.1 0 0 0 6 0 A2VDD2 8.75e-24 Dynein light chain Tctex-type 5-B (Tctex1 domain-containing protein 1-B) Xenopus laevis (African clawed frog) NA NA 16756 XM_044328020.1 63 0 12 0 5 Q96FG2 3.87e-71 ELMO domain-containing protein 3 (RNA-binding motif and ELMO domain-containing protein 1) (RNA-binding motif protein 29) (RNA-binding protein 29) Homo sapiens (Human) NA GO:0005737; GO:0005856; GO:0005886; GO:0032420; GO:0060091 16757 XM_029347033.2 37 32 46 61 87 NA NA NA NA NA NA 16758 XR_006391670.1 0 0 93 19 52 NA NA NA NA NA NA 16759 XM_029323993.2 805 623 578 756 820 Q28HF8 4.51e-127 Sodium/bile acid cotransporter 7 (Na(+)/bile acid cotransporter 7) (Solute carrier family 10 member 7) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) sodium ion transport [GO:0006814] GO:0000139; GO:0005789; GO:0005886; GO:0006814; GO:0015293 16760 XM_044320509.1 491 329 321 1335 1366 Q7RTR2 7.46e-47 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16761 XM_044320509.1 491 329 321 1335 1366 Q7RTR2 3.41e-42 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16762 XM_044320509.1 491 329 321 1335 1366 Q7RTR2 8.06e-42 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16763 XM_044320509.1 491 329 321 1335 1366 Q7RTR2 2.44e-40 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16764 XM_044320509.1 491 329 321 1335 1366 Q7RTR2 3.58e-37 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16765 XM_044320509.1 491 329 321 1335 1366 Q7RTR2 1.46e-26 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16766 XM_029330538.2 4510 4696 2810 4751 4796 Q5RKI1 0 Eukaryotic initiation factor 4A-II (eIF-4A-II) (eIF4A-II) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-2) Rattus norvegicus (Rat) cellular response to leukemia inhibitory factor [GO:1990830]; cytoplasmic translational initiation [GO:0002183]; negative regulation of RNA-dependent RNA polymerase activity [GO:1900260] GO:0002183; GO:0003723; GO:0003724; GO:0003743; GO:0005524; GO:0016887; GO:0048471; GO:1900260; GO:1990830 16767 XM_044311531.1 1 0 4 0 7 NA NA NA NA NA NA 16768 XM_029336625.2 128 134 81 129 112 Q6AY46 1.12e-108 tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A (EC 2.1.1.220) (mRNA methyladenosine-N(1)-methyltransferase catalytic subunit TRMT61A) (EC 2.1.1.-) (tRNA(m1A58)-methyltransferase subunit TRMT61A) (tRNA(m1A58)MTase subunit TRMT61A) Rattus norvegicus (Rat) mRNA methylation [GO:0080009]; tRNA methylation [GO:0030488] GO:0005634; GO:0016429; GO:0030488; GO:0031515; GO:0061953; GO:0080009 16769 XM_044318134.1 1 13 0 9 4 NA NA NA NA NA NA 16770 XM_029340969.2 2366 891 536 8492 3603 NA NA NA NA NA NA 16771 XM_044323941.1 635 483 366 281 435 NA NA NA NA NA NA 16772 XM_044312842.1 77 93 65 52 148 NA NA NA NA NA NA 16773 XM_029330393.2 1495 839 644 1111 797 Q5JVF3 0 PCI domain-containing protein 2 (CSN12-like protein) Homo sapiens (Human) heterochromatin organization [GO:0070828]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lymphoid progenitor cell differentiation [GO:1905457]; negative regulation of transcription initiation by RNA polymerase II [GO:0060633]; poly(A)+ mRNA export from nucleus [GO:0016973]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000973]; protein transport [GO:0015031]; regulation of mRNA stability [GO:0043488]; spleen development [GO:0048536]; transcription elongation by RNA polymerase II promoter [GO:0006368] GO:0000973; GO:0003690; GO:0003723; GO:0005634; GO:0005737; GO:0006368; GO:0015031; GO:0016973; GO:0043066; GO:0043488; GO:0044615; GO:0045579; GO:0045893; GO:0048536; GO:0060633; GO:0070390; GO:0070828; GO:0090267; GO:1905457; GO:2000117 16774 XM_029340606.2 0 11 108 91 70 NA NA NA NA NA NA 16775 XM_029324472.2 533 465 245 586 413 Q96ES7 1.33e-122 SAGA-associated factor 29 (Coiled-coil domain-containing protein 101) (SAGA complex-associated factor 29) Homo sapiens (Human) chromatin organization [GO:0006325]; establishment of protein localization to chromatin [GO:0071169]; histone acetylation [GO:0016573]; histone H3 acetylation [GO:0043966]; histone H3-K14 acetylation [GO:0044154]; monoubiquitinated histone deubiquitination [GO:0035521]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of cell cycle [GO:0051726]; regulation of cell division [GO:0051302]; regulation of DNA repair [GO:0006282]; regulation of DNA-templated transcription [GO:0006355]; regulation of embryonic development [GO:0045995]; regulation of histone deacetylation [GO:0031063]; regulation of RNA splicing [GO:0043484]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tubulin deacetylation [GO:0090043] GO:0000124; GO:0005634; GO:0006282; GO:0006325; GO:0006355; GO:0006357; GO:0016573; GO:0031063; GO:0035064; GO:0035521; GO:0035522; GO:0043484; GO:0043966; GO:0044154; GO:0045893; GO:0045995; GO:0051302; GO:0051726; GO:0070461; GO:0071169; GO:0072686; GO:0090043; GO:0140672 16776 XM_044325353.1 5 0 18 0 57 P48733 5.2e-28 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Bos taurus (Bovine) antibacterial innate immune response [GO:0140367]; defense response to Gram-negative bacterium [GO:0050829] GO:0000922; GO:0005201; GO:0005509; GO:0005576; GO:0005929; GO:0016020; GO:0016323; GO:0016324; GO:0031012; GO:0050829; GO:0060170; GO:0140367 16777 XM_029330699.2 328 251 157 88 92 O61585 0 Katanin p80 WD40 repeat-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin) Strongylocentrotus purpuratus (Purple sea urchin) cell cycle [GO:0007049]; cell division [GO:0051301]; microtubule depolymerization [GO:0007019]; microtubule severing [GO:0051013] GO:0000922; GO:0005737; GO:0005813; GO:0005819; GO:0005874; GO:0007019; GO:0007049; GO:0008017; GO:0008352; GO:0051013; GO:0051301 16778 XM_044317402.1 2190 2554 2111 3162 1090 NA NA NA NA NA NA 16779 XM_044321888.1 644 428 401 937 892 F1NTD6 0 Activating signal cointegrator 1 complex subunit 3 (EC 3.6.4.12) Gallus gallus (Chicken) cell population proliferation [GO:0008283]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA duplex unwinding [GO:0032508]; rescue of stalled ribosome [GO:0072344]; ribosome-associated ubiquitin-dependent protein catabolic process [GO:1990116] GO:0003676; GO:0005524; GO:0005634; GO:0005829; GO:0006307; GO:0008283; GO:0016607; GO:0016887; GO:0032508; GO:0043138; GO:0072344; GO:0099053; GO:1990116; GO:1990391 16780 XM_029353942.2 73 0 0 0 20 Q9H0J4 8.47e-43 Glutamine-rich protein 2 Homo sapiens (Human) cell projection assembly [GO:0030031]; flagellated sperm motility [GO:0030317]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059] GO:0005737; GO:0030031; GO:0030317; GO:0031965; GO:0036126; GO:2000059 16781 XM_029344853.2 918 854 508 1227 804 Q5U5D4 0 GATOR complex protein MIOS-A Xenopus laevis (African clawed frog) NA GO:0005765 16782 XM_029340622.2 7081 8114 6043 8896 9697 Q28XE2 3.47e-49 Acidic leucine-rich nuclear phosphoprotein 32 family member A Drosophila pseudoobscura pseudoobscura (Fruit fly) nucleocytoplasmic transport [GO:0006913] GO:0005634; GO:0005737; GO:0005783; GO:0006913; GO:0048471 16783 XM_029341335.2 356 178 212 546 583 NA NA NA NA NA NA 16784 XM_044322181.1 90 7 82 147 37 NA NA NA NA NA NA 16785 XM_044314810.1 0 0 0 0 109 NA NA NA NA NA NA 16786 XM_029341080.2 219 189 72 192 108 S4R2K0 2.57e-43 Peptide deformylase, mitochondrial (EC 3.5.1.88) (Polypeptide deformylase) Mus musculus (Mouse) co-translational protein modification [GO:0043686]; N-terminal protein amino acid modification [GO:0031365]; peptidyl-methionine modification [GO:0018206]; positive regulation of cell population proliferation [GO:0008284]; translation [GO:0006412] GO:0005739; GO:0006412; GO:0008284; GO:0018206; GO:0031365; GO:0042586; GO:0043686; GO:0046872 16787 XR_006396838.1 0 163 0 30 45 NA NA NA NA NA NA 16788 XM_029340015.2 299 183 146 390 347 Q6DRJ4 4.72e-125 Protein KRI1 homolog Danio rerio (Zebrafish) (Brachydanio rerio) definitive hemopoiesis [GO:0060216]; endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000447]; ribosome biogenesis [GO:0042254] GO:0000447; GO:0005730; GO:0030686; GO:0042254; GO:0060216 16789 XR_003828271.2 119 39 62 149 256 NA NA NA NA NA NA 16790 XM_044322923.1 297 155 113 153 90 NA NA NA NA NA NA 16791 XM_044322603.1 9 0 11 0 0 NA NA NA NA NA NA 16792 XM_044307411.1 141 43 108 92 130 NA NA NA NA NA NA 16793 XM_044314247.1 231 104 77 110 56 NA NA NA NA NA NA 16794 XM_044328498.1 862 527 765 1268 1466 Q9BYK8 6.56e-168 Helicase with zinc finger domain 2 (ATP-dependent helicase PRIC285) (Helicase with zinc finger 2, transcriptional coactivator) (PPAR-alpha-interacting complex protein 285) (PPAR-gamma DNA-binding domain-interacting protein 1) (PDIP1) (PPAR-gamma DBD-interacting protein 1) (Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein) (EC 3.6.4.-) Homo sapiens (Human) nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000184; GO:0003677; GO:0003723; GO:0003724; GO:0004540; GO:0005524; GO:0005654; GO:0005737; GO:0016020; GO:0030374; GO:0045944; GO:0046872 16795 XM_044328498.1 862 527 765 1268 1466 Q9BYK8 4.51e-104 Helicase with zinc finger domain 2 (ATP-dependent helicase PRIC285) (Helicase with zinc finger 2, transcriptional coactivator) (PPAR-alpha-interacting complex protein 285) (PPAR-gamma DNA-binding domain-interacting protein 1) (PDIP1) (PPAR-gamma DBD-interacting protein 1) (Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein) (EC 3.6.4.-) Homo sapiens (Human) nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000184; GO:0003677; GO:0003723; GO:0003724; GO:0004540; GO:0005524; GO:0005654; GO:0005737; GO:0016020; GO:0030374; GO:0045944; GO:0046872 16796 XM_044328498.1 862 527 765 1268 1466 Q9BYK8 7.34e-27 Helicase with zinc finger domain 2 (ATP-dependent helicase PRIC285) (Helicase with zinc finger 2, transcriptional coactivator) (PPAR-alpha-interacting complex protein 285) (PPAR-gamma DNA-binding domain-interacting protein 1) (PDIP1) (PPAR-gamma DBD-interacting protein 1) (Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein) (EC 3.6.4.-) Homo sapiens (Human) nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000184; GO:0003677; GO:0003723; GO:0003724; GO:0004540; GO:0005524; GO:0005654; GO:0005737; GO:0016020; GO:0030374; GO:0045944; GO:0046872 16797 XM_029353921.2 203 189 179 261 216 Q9Z1Z3 3.19e-94 Epsin-2 (EPS-15-interacting protein 2) Rattus norvegicus (Rat) embryonic organ development [GO:0048568]; endocytosis [GO:0006897]; in utero embryonic development [GO:0001701]; negative regulation of sprouting angiogenesis [GO:1903671]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; Notch signaling pathway [GO:0007219]; positive regulation of Notch signaling pathway [GO:0045747]; regulation of endocytosis [GO:0030100] GO:0001701; GO:0005543; GO:0005768; GO:0005886; GO:0006897; GO:0007219; GO:0030100; GO:0030125; GO:0030128; GO:0030276; GO:0030948; GO:0045747; GO:0048568; GO:1903671 16798 XM_029336915.2 1212 911 939 1046 1313 Q6P9S0 4.19e-59 Protein MTSS 2 (MTSS1-like protein) Mus musculus (Mouse) activation of GTPase activity [GO:0090630]; cell projection assembly [GO:0030031]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; lamellipodium organization [GO:0097581]; membrane organization [GO:0061024]; plasma membrane organization [GO:0007009] GO:0001726; GO:0003779; GO:0003785; GO:0005096; GO:0005543; GO:0005546; GO:0005886; GO:0007009; GO:0009898; GO:0015629; GO:0030027; GO:0030031; GO:0030864; GO:0031267; GO:0032587; GO:0036120; GO:0061024; GO:0090630; GO:0097581 16799 XM_044325587.1 816 623 706 958 1176 P78536 4.56e-24 Disintegrin and metalloproteinase domain-containing protein 17 (ADAM 17) (EC 3.4.24.86) (Snake venom-like protease) (TNF-alpha convertase) (TNF-alpha-converting enzyme) (CD antigen CD156b) Homo sapiens (Human) amyloid precursor protein catabolic process [GO:0042987]; B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; protein processing [GO:0016485]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; response to xenobiotic stimulus [GO:0009410]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; wound healing, spreading of epidermal cells [GO:0035313] GO:0000139; GO:0001666; GO:0001934; GO:0002446; GO:0002467; GO:0002690; GO:0004175; GO:0004222; GO:0005112; GO:0005138; GO:0005178; GO:0005737; GO:0005788; GO:0005829; GO:0005886; GO:0006508; GO:0006509; GO:0007155; GO:0007173; GO:0007219; GO:0007220; GO:0008233; GO:0008237; GO:0008284; GO:0009410; GO:0009986; GO:0010820; GO:0015629; GO:0016020; GO:0016324; GO:0016485; GO:0017124; GO:0030165; GO:0030183; GO:0030307; GO:0030335; GO:0030511; GO:0030512; GO:0032496; GO:0032722; GO:0033025; GO:0033077; GO:0033627; GO:0035313; GO:0035624; GO:0042987; GO:0043536; GO:0045121; GO:0045737; GO:0045741; GO:0046872; GO:0048536; GO:0048870; GO:0050830; GO:0071403; GO:0120163; GO:1900087; GO:1902945; GO:1903265; GO:1905564 16800 XR_006397739.1 56 117 25 55 92 NA NA NA NA NA NA 16801 XM_029332185.2 4 18 0 19 8 NA NA NA NA NA NA 16802 XM_029339775.2 4892 8029 4030 6508 2572 P18421 1.25e-116 Proteasome subunit beta type-1 (Macropain subunit C5) (Multicatalytic endopeptidase complex subunit C5) (Proteasome component C5) (Proteasome gamma chain) Rattus norvegicus (Rat) proteasomal protein catabolic process [GO:0010498] GO:0000502; GO:0005634; GO:0005737; GO:0005839; GO:0010498; GO:0019774 16803 XM_044311357.1 5 0 16 1 6 NA NA NA NA NA NA 16804 XM_029339763.2 435 491 277 180 111 NA NA NA NA NA NA 16805 XM_044323551.1 446 299 221 360 291 Q95LZ5 3.68e-110 Tetratricopeptide repeat protein 16 (TPR repeat protein 16) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA NA 16806 XM_044310985.1 1 52 17 13 2246 Q8CG08 8.75e-34 Collagen triple helix repeat-containing protein 1 Rattus norvegicus (Rat) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005581; GO:0005615; GO:0005737; GO:0016477; GO:0016528; GO:0017147; GO:0031012; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0090090; GO:0090103; GO:0090177 16807 XM_044324101.1 24 0 16 21 4 NA NA NA NA NA NA 16808 XM_044309858.1 465 311 140 247 441 NA NA NA NA NA NA 16809 XR_003823643.2 57 55 40 60 277 NA NA NA NA NA NA 16810 XM_029355898.2 122 819 153 360 230 Q80TE0 0 RNA polymerase II-associated protein 1 Mus musculus (Mouse) transcription by RNA polymerase II [GO:0006366] GO:0000428; GO:0003677; GO:0005634; GO:0006366; GO:0016779; GO:0030880 16811 XM_044323867.1 315 236 56 49 95 NA NA NA NA NA NA 16812 XM_029333183.2 3126 2896 1779 2115 2258 NA NA NA NA NA NA 16813 XM_044315170.1 148 141 0 0 151 P97321 7.27e-35 Prolyl endopeptidase FAP (EC 3.4.21.26) (Dipeptidyl peptidase FAP) (EC 3.4.14.5) (Fibroblast activation protein alpha) (FAPalpha) (Gelatine degradation protease FAP) (EC 3.4.21.-) (Integral membrane serine protease) (Post-proline cleaving enzyme) (Serine integral membrane protease) (SIMP) (Surface-expressed protease) (Seprase) [Cleaved into: Antiplasmin-cleaving enzyme FAP, soluble form (APCE) (EC 3.4.14.5) (EC 3.4.21.-) (EC 3.4.21.26)] Mus musculus (Mouse) angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; melanocyte apoptotic process [GO:1902362]; melanocyte proliferation [GO:0097325]; negative regulation of cell proliferation involved in contact inhibition [GO:0060244]; negative regulation of extracellular matrix disassembly [GO:0010716]; negative regulation of extracellular matrix organization [GO:1903054]; positive regulation of execution phase of apoptosis [GO:1900119]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of cell cycle [GO:0051726]; regulation of collagen catabolic process [GO:0010710] GO:0001525; GO:0002020; GO:0004175; GO:0004252; GO:0005178; GO:0005615; GO:0005886; GO:0006508; GO:0007155; GO:0008233; GO:0008236; GO:0008239; GO:0009986; GO:0010710; GO:0010716; GO:0030027; GO:0031258; GO:0032587; GO:0042802; GO:0042803; GO:0043542; GO:0045177; GO:0045178; GO:0051603; GO:0051726; GO:0060244; GO:0070161; GO:0097325; GO:1900119; GO:1902362; GO:1903054; GO:1905368 16814 XM_044315170.1 148 141 0 0 151 P97321 7.27e-35 Prolyl endopeptidase FAP (EC 3.4.21.26) (Dipeptidyl peptidase FAP) (EC 3.4.14.5) (Fibroblast activation protein alpha) (FAPalpha) (Gelatine degradation protease FAP) (EC 3.4.21.-) (Integral membrane serine protease) (Post-proline cleaving enzyme) (Serine integral membrane protease) (SIMP) (Surface-expressed protease) (Seprase) [Cleaved into: Antiplasmin-cleaving enzyme FAP, soluble form (APCE) (EC 3.4.14.5) (EC 3.4.21.-) (EC 3.4.21.26)] Mus musculus (Mouse) angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; melanocyte apoptotic process [GO:1902362]; melanocyte proliferation [GO:0097325]; negative regulation of cell proliferation involved in contact inhibition [GO:0060244]; negative regulation of extracellular matrix disassembly [GO:0010716]; negative regulation of extracellular matrix organization [GO:1903054]; positive regulation of execution phase of apoptosis [GO:1900119]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of cell cycle [GO:0051726]; regulation of collagen catabolic process [GO:0010710] GO:0001525; GO:0002020; GO:0004175; GO:0004252; GO:0005178; GO:0005615; GO:0005886; GO:0006508; GO:0007155; GO:0008233; GO:0008236; GO:0008239; GO:0009986; GO:0010710; GO:0010716; GO:0030027; GO:0031258; GO:0032587; GO:0042802; GO:0042803; GO:0043542; GO:0045177; GO:0045178; GO:0051603; GO:0051726; GO:0060244; GO:0070161; GO:0097325; GO:1900119; GO:1902362; GO:1903054; GO:1905368 16815 XM_044315170.1 148 141 0 0 151 P97321 7.27e-35 Prolyl endopeptidase FAP (EC 3.4.21.26) (Dipeptidyl peptidase FAP) (EC 3.4.14.5) (Fibroblast activation protein alpha) (FAPalpha) (Gelatine degradation protease FAP) (EC 3.4.21.-) (Integral membrane serine protease) (Post-proline cleaving enzyme) (Serine integral membrane protease) (SIMP) (Surface-expressed protease) (Seprase) [Cleaved into: Antiplasmin-cleaving enzyme FAP, soluble form (APCE) (EC 3.4.14.5) (EC 3.4.21.-) (EC 3.4.21.26)] Mus musculus (Mouse) angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; melanocyte apoptotic process [GO:1902362]; melanocyte proliferation [GO:0097325]; negative regulation of cell proliferation involved in contact inhibition [GO:0060244]; negative regulation of extracellular matrix disassembly [GO:0010716]; negative regulation of extracellular matrix organization [GO:1903054]; positive regulation of execution phase of apoptosis [GO:1900119]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of cell cycle [GO:0051726]; regulation of collagen catabolic process [GO:0010710] GO:0001525; GO:0002020; GO:0004175; GO:0004252; GO:0005178; GO:0005615; GO:0005886; GO:0006508; GO:0007155; GO:0008233; GO:0008236; GO:0008239; GO:0009986; GO:0010710; GO:0010716; GO:0030027; GO:0031258; GO:0032587; GO:0042802; GO:0042803; GO:0043542; GO:0045177; GO:0045178; GO:0051603; GO:0051726; GO:0060244; GO:0070161; GO:0097325; GO:1900119; GO:1902362; GO:1903054; GO:1905368 16816 XM_029334341.2 1141 254 657 1179 256 E9PUQ8 0 Diacylglycerol kinase delta (DAG kinase delta) (EC 2.7.1.107) Mus musculus (Mouse) diacylglycerol metabolic process [GO:0046339]; endocytosis [GO:0006897]; intracellular signal transduction [GO:0035556]; lipid phosphorylation [GO:0046834]; negative regulation of protein kinase C signaling [GO:0090038]; phosphatidic acid biosynthetic process [GO:0006654]; positive regulation of clathrin-dependent endocytosis [GO:2000370]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; protein transport [GO:0015031]; response to organic substance [GO:0010033] GO:0004143; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0005905; GO:0006654; GO:0006897; GO:0007205; GO:0010033; GO:0015031; GO:0019900; GO:0031410; GO:0035556; GO:0042802; GO:0042803; GO:0045742; GO:0046339; GO:0046834; GO:0046872; GO:0046982; GO:0090038; GO:2000370 16817 XR_006396902.1 41 25 0 22 32 NA NA NA NA NA NA 16818 XM_044312353.1 67 1 15 19 55 NA NA NA NA NA NA 16819 XM_044319209.1 1745 952 570 1610 2012 Q5R481 4.8e-156 Septin-7 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cell division [GO:0051301]; cilium assembly [GO:0060271]; regulation of embryonic cell shape [GO:0016476]; spermatogenesis [GO:0007283] GO:0000776; GO:0005525; GO:0005819; GO:0005930; GO:0007049; GO:0007283; GO:0016476; GO:0030154; GO:0030496; GO:0031105; GO:0031514; GO:0032154; GO:0051301; GO:0060271 16820 XM_044316597.1 0 2 0 18 0 NA NA NA NA NA NA 16821 XM_029338833.2 1658 1290 824 1332 1896 Q9UMS4 0 Pre-mRNA-processing factor 19 (EC 2.3.2.27) (Nuclear matrix protein 200) (PRP19/PSO4 homolog) (hPso4) (RING-type E3 ubiquitin transferase PRP19) (Senescence evasion factor) Homo sapiens (Human) DNA damage checkpoint signaling [GO:0000077]; double-strand break repair via nonhomologous end joining [GO:0006303]; lipid biosynthetic process [GO:0008610]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of neuron differentiation [GO:0045666]; proteasomal protein catabolic process [GO:0010498]; protein K63-linked ubiquitination [GO:0070534]; protein localization [GO:0008104]; protein polyubiquitination [GO:0000209]; spliceosomal complex assembly [GO:0000245]; spliceosomal tri-snRNP complex assembly [GO:0000244] GO:0000077; GO:0000209; GO:0000244; GO:0000245; GO:0000398; GO:0000974; GO:0004842; GO:0005634; GO:0005654; GO:0005681; GO:0005737; GO:0005811; GO:0005819; GO:0006303; GO:0008104; GO:0008610; GO:0010498; GO:0016020; GO:0016607; GO:0034450; GO:0035861; GO:0042802; GO:0045666; GO:0048026; GO:0048711; GO:0061630; GO:0070534; GO:0071006; GO:0071007; GO:0071013 16822 XM_044315769.1 308 173 75 205 77 Q96AY4 8.54e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16823 XM_044315769.1 308 173 75 205 77 Q96AY4 1.21e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16824 XM_044315769.1 308 173 75 205 77 Q96AY4 1.62e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16825 XM_044315769.1 308 173 75 205 77 Q96AY4 2.36e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16826 XM_044315769.1 308 173 75 205 77 Q96AY4 2.37e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16827 XM_044315769.1 308 173 75 205 77 Q96AY4 3.26e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16828 XM_044315769.1 308 173 75 205 77 Q96AY4 4.02e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16829 XM_044315769.1 308 173 75 205 77 Q96AY4 4.8e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16830 XM_044329079.1 1430 862 763 1709 1374 Q9BXF3 2.62e-51 Chromatin remodeling regulator CECR2 (Cat eye syndrome critical region protein 2) Homo sapiens (Human) apoptotic DNA fragmentation [GO:0006309]; chromatin remodeling [GO:0006338]; cochlea development [GO:0090102]; cytoskeleton organization [GO:0007010]; cytoskeleton-dependent cytokinesis [GO:0061640]; execution phase of apoptosis [GO:0097194]; inner ear receptor cell stereocilium organization [GO:0060122]; neural fold formation [GO:0001842]; neural tube closure [GO:0001843]; single fertilization [GO:0007338]; vesicle-mediated transport [GO:0016192] GO:0000791; GO:0001842; GO:0001843; GO:0005634; GO:0006309; GO:0006338; GO:0007010; GO:0007338; GO:0016192; GO:0060122; GO:0061640; GO:0090102; GO:0090537; GO:0097194; GO:0140658 16831 XM_044329079.1 1430 862 763 1709 1374 Q9BXF3 2.94e-32 Chromatin remodeling regulator CECR2 (Cat eye syndrome critical region protein 2) Homo sapiens (Human) apoptotic DNA fragmentation [GO:0006309]; chromatin remodeling [GO:0006338]; cochlea development [GO:0090102]; cytoskeleton organization [GO:0007010]; cytoskeleton-dependent cytokinesis [GO:0061640]; execution phase of apoptosis [GO:0097194]; inner ear receptor cell stereocilium organization [GO:0060122]; neural fold formation [GO:0001842]; neural tube closure [GO:0001843]; single fertilization [GO:0007338]; vesicle-mediated transport [GO:0016192] GO:0000791; GO:0001842; GO:0001843; GO:0005634; GO:0006309; GO:0006338; GO:0007010; GO:0007338; GO:0016192; GO:0060122; GO:0061640; GO:0090102; GO:0090537; GO:0097194; GO:0140658 16832 XM_044312264.1 20 55 11 31 14 NA NA NA NA NA NA 16833 XM_029355538.2 289 0 198 66 128 NA NA NA NA NA NA 16834 XM_044310627.1 10725 12118 7016 18110 21156 P13607 0 Sodium/potassium-transporting ATPase subunit alpha (Na(+)/K(+) ATPase alpha subunit) (EC 7.2.2.13) (Sodium pump subunit alpha) Drosophila melanogaster (Fruit fly) adult locomotory behavior [GO:0008344]; cation transport [GO:0006812]; cellular potassium ion homeostasis [GO:0030007]; cellular sodium ion homeostasis [GO:0006883]; chemical synaptic transmission [GO:0007268]; determination of adult lifespan [GO:0008340]; jump response [GO:0007630]; locomotory behavior [GO:0007626]; neuromuscular process [GO:0050905]; potassium ion import across plasma membrane [GO:1990573]; proton transmembrane transport [GO:1902600]; regulation of tube diameter, open tracheal system [GO:0035158]; regulation of tube length, open tracheal system [GO:0035159]; response to mechanical stimulus [GO:0009612]; response to temperature stimulus [GO:0009266]; sensory perception of sound [GO:0007605]; septate junction assembly [GO:0019991]; sodium ion export across plasma membrane [GO:0036376]; synaptic assembly at neuromuscular junction [GO:0051124]; tissue homeostasis [GO:0001894]; trachea morphogenesis [GO:0060439] GO:0001894; GO:0005391; GO:0005524; GO:0005634; GO:0005737; GO:0005886; GO:0005890; GO:0005918; GO:0006812; GO:0006883; GO:0007268; GO:0007605; GO:0007626; GO:0007630; GO:0008340; GO:0008344; GO:0009266; GO:0009612; GO:0016323; GO:0016887; GO:0019829; GO:0019991; GO:0030007; GO:0035158; GO:0035159; GO:0036376; GO:0045202; GO:0050905; GO:0051124; GO:0060439; GO:1902600; GO:1990573 16835 XM_029349001.2 16 17 12 72 44 NA NA NA NA NA NA 16836 XM_029342645.2 153 68 148 73 156 Q8VY74 5.11e-21 U11/U12 small nuclear ribonucleoprotein 35 kDa protein (U11/U12 snRNP 35 kDa protein) (U11/U12-35K) Arabidopsis thaliana (Mouse-ear cress) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0003729; GO:0005634; GO:0005689; GO:0016607; GO:0017069; GO:0034693 16837 XM_029334842.2 43 20 36 40 70 NA NA NA NA NA NA 16838 XM_029335777.2 9 13 17 18 74 NA NA NA NA NA NA 16839 XM_029327231.2 290 0 101 0 0 Q6ZQR2 4.94e-33 Cilia- and flagella-associated protein 77 Homo sapiens (Human) NA GO:0005929 16840 XM_044311178.1 3 0 20 3 0 NA NA NA NA NA NA 16841 XM_044324633.1 0 0 0 0 6 NA NA NA NA NA NA 16842 XM_044319038.1 199 141 85 145 255 Q91X20 7.42e-137 Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2-like protein) Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; histone H3-K4 methylation [GO:0051568]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to estrogen [GO:0043627]; transcription initiation-coupled chromatin remodeling [GO:0045815] GO:0000791; GO:0000976; GO:0005634; GO:0005654; GO:0006974; GO:0008013; GO:0008284; GO:0035097; GO:0043627; GO:0044665; GO:0044666; GO:0045815; GO:0045944; GO:0046872; GO:0048188; GO:0051568; GO:0071339 16843 XM_044313723.1 0 90 17 70 38 Q2KJC3 3.83e-152 Macrophage-expressed gene 1 protein (Macrophage gene 1 protein) (Mpg-1) (Perforin-2) (P-2) Bos taurus (Bovine) antibacterial innate immune response [GO:0140367]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; disruption by host of symbiont membrane [GO:0052337] GO:0030659; GO:0031410; GO:0042742; GO:0045335; GO:0050829; GO:0050830; GO:0052337; GO:0140367 16844 XM_044309848.1 0 4 5 18 6 Q12933 5.1e-61 TNF receptor-associated factor 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF2) (RING-type E3 ubiquitin transferase TRAF2) (Tumor necrosis factor type 2 receptor-associated protein 3) Homo sapiens (Human) activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular response to nitric oxide [GO:0071732]; interleukin-17-mediated signaling pathway [GO:0097400]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; mRNA stabilization [GO:0048255]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron death [GO:1901215]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein K63-linked ubiquitination [GO:0070534]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin production [GO:0002637]; regulation of protein-containing complex assembly [GO:0043254]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; signal transduction involved in regulation of gene expression [GO:0023019]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000151; GO:0002637; GO:0002726; GO:0002947; GO:0004842; GO:0005164; GO:0005174; GO:0005654; GO:0005829; GO:0005938; GO:0007165; GO:0007250; GO:0008270; GO:0009898; GO:0012506; GO:0019899; GO:0019901; GO:0019903; GO:0023019; GO:0030163; GO:0030674; GO:0031435; GO:0031625; GO:0031996; GO:0032743; GO:0033209; GO:0034351; GO:0034976; GO:0035631; GO:0042802; GO:0042981; GO:0043120; GO:0043122; GO:0043123; GO:0043254; GO:0043507; GO:0044877; GO:0045121; GO:0046330; GO:0046625; GO:0048255; GO:0051091; GO:0051092; GO:0051865; GO:0065003; GO:0070059; GO:0070534; GO:0071732; GO:0097057; GO:0097300; GO:0097400; GO:1901215; GO:1903265; GO:1903721; GO:1990604; GO:2001238 16845 XM_029349733.2 161 157 102 196 0 Q6PBT5 1.2e-151 Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 (EC 1.8.1.-) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005634; GO:0016491; GO:0030017; GO:0050660 16846 XM_029340411.2 0 0 0 25 0 Q6IPR3 6.07e-44 tRNA wybutosine-synthesizing protein 3 homolog (tRNA-yW-synthesizing protein 3) (EC 2.1.1.282) (tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase) Homo sapiens (Human) tRNA methylation [GO:0030488] GO:0005737; GO:0008175; GO:0030488 16847 XR_003824169.2 266 167 183 231 305 NA NA NA NA NA NA 16848 XM_029339625.2 54 135 108 169 40 Q9Y394 1.37e-85 Dehydrogenase/reductase SDR family member 7 (EC 1.1.1.-) (Retinal short-chain dehydrogenase/reductase 4) (retSDR4) (Short chain dehydrogenase/reductase family 34C member 1) (Protein SDR34C1) Homo sapiens (Human) NA GO:0004090; GO:0005789; GO:0016020; GO:0016616; GO:0052650 16849 XM_029353527.2 10834 11321 6681 14454 3845 Q5BK63 7.52e-112 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (Complex I-39kD) (CI-39kD) (NADH-ubiquinone oxidoreductase 39 kDa subunit) (Sperm flagella protein 3) Rattus norvegicus (Rat) circadian rhythm [GO:0007623]; mitochondrial respiratory chain complex I assembly [GO:0032981]; response to glucose [GO:0009749]; ubiquinone-6 biosynthetic process [GO:1901006] GO:0003954; GO:0005739; GO:0005743; GO:0005747; GO:0005759; GO:0007623; GO:0009749; GO:0031966; GO:0032981; GO:0044877; GO:1901006 16850 XM_029331298.2 111 109 100 95 55 Q9CXC3 1.85e-51 Mitochondrial genome maintenance exonuclease 1 (EC 3.1.-.-) Mus musculus (Mouse) mitochondrial DNA repair [GO:0043504]; mitochondrial DNA replication [GO:0006264]; mitochondrial genome maintenance [GO:0000002] GO:0000002; GO:0005739; GO:0006264; GO:0008297; GO:0043504 16851 XM_029343191.2 404 410 232 540 844 NA NA NA NA NA NA 16852 XM_029335157.2 190 125 127 101 1178 Q96B70 1.26e-24 Leukocyte receptor cluster member 9 Homo sapiens (Human) NA GO:0046872 16853 XR_006396753.1 18 3 2 51 25 NA NA NA NA NA NA 16854 XM_029342130.2 350 611 249 1158 649 NA NA NA NA NA NA 16855 XM_029339672.2 0 74 0 12 148 P20483 1.11e-52 M-phase inducer phosphatase (EC 3.1.3.48) (Cdc25-like protein) (Protein string) Drosophila melanogaster (Fruit fly) cell division [GO:0051301]; centriole replication [GO:0007099]; G2/M transition of mitotic cell cycle [GO:0000086]; gastrulation [GO:0007369]; Golgi organization [GO:0007030]; histoblast morphogenesis [GO:0007488]; negative regulation of cell size [GO:0045792]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of G2/MI transition of meiotic cell cycle [GO:0110032]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of mitotic cell cycle, embryonic [GO:0045977]; protein dephosphorylation [GO:0006470]; regulation of mitotic cell cycle [GO:0007346] GO:0000086; GO:0004725; GO:0005634; GO:0005694; GO:0005737; GO:0006470; GO:0007030; GO:0007099; GO:0007346; GO:0007369; GO:0007488; GO:0008284; GO:0010971; GO:0045792; GO:0045931; GO:0045977; GO:0051301; GO:0110032 16856 XR_006397116.1 11 9 23 45 7 NA NA NA NA NA NA 16857 XM_044319913.1 2 5 7 3 3 NA NA NA NA NA NA 16858 XM_029331323.2 368 689 338 713 462 O95935 7.86e-94 T-box transcription factor TBX18 (T-box protein 18) Homo sapiens (Human) cell fate specification [GO:0001708]; cochlea morphogenesis [GO:0090103]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation [GO:0060829]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of SA node cell action potential [GO:0098907]; regulation of transcription by RNA polymerase II [GO:0006357]; sinoatrial node cell development [GO:0060931]; sinoatrial node cell fate commitment [GO:0060930]; sinoatrial node development [GO:0003163]; smooth muscle cell differentiation [GO:0051145]; somitogenesis [GO:0001756]; ureter development [GO:0072189] GO:0000785; GO:0000976; GO:0000978; GO:0000981; GO:0001227; GO:0001708; GO:0001756; GO:0003163; GO:0005634; GO:0005654; GO:0006357; GO:0016331; GO:0042803; GO:0045893; GO:0051145; GO:0060829; GO:0060930; GO:0060931; GO:0072189; GO:0090103; GO:0090571; GO:0098907; GO:1990837 16859 XM_044328649.1 8 15 32 22 31 Q8VCK5 1.01e-163 Kelch-like protein 20 (Kelch-like ECT2-interacting protein) Mus musculus (Mouse) Golgi to endosome transport [GO:0006895]; negative regulation of apoptotic process [GO:0043066]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K33-linked ubiquitination [GO:1990390]; protein transport [GO:0015031]; protein ubiquitination [GO:0016567] GO:0003779; GO:0004842; GO:0005737; GO:0005794; GO:0005802; GO:0005829; GO:0006895; GO:0015031; GO:0016567; GO:0016605; GO:0019964; GO:0030424; GO:0030425; GO:0031463; GO:0043066; GO:0043161; GO:0048471; GO:1990390 16860 XM_044320251.1 126 0 89 0 117 NA NA NA NA NA NA 16861 XM_044328875.1 25 6 13 21 124 NA NA NA NA NA NA 16862 XM_029337739.2 2440 1559 820 1572 1429 Q9ULV1 6.39e-175 Frizzled-4 (Fz-4) (hFz4) (FzE4) (CD antigen CD344) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to retinoic acid [GO:0071300]; cerebellum vasculature morphogenesis [GO:0061301]; extracellular matrix-cell signaling [GO:0035426]; locomotion involved in locomotory behavior [GO:0031987]; negative regulation of cell-substrate adhesion [GO:0010812]; neuron differentiation [GO:0030182]; non-canonical Wnt signaling pathway [GO:0035567]; Norrin signaling pathway [GO:0110135]; positive regulation of cell migration [GO:0030335]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of neuron projection arborization [GO:0150012]; progesterone secretion [GO:0042701]; regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030947]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; retinal blood vessel morphogenesis [GO:0061304]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; vasculogenesis [GO:0001570]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway, calcium modulating pathway [GO:0007223] GO:0001540; GO:0001570; GO:0004896; GO:0004930; GO:0005615; GO:0005886; GO:0005911; GO:0007223; GO:0007605; GO:0009986; GO:0010812; GO:0016055; GO:0017147; GO:0019955; GO:0030165; GO:0030182; GO:0030335; GO:0030425; GO:0030669; GO:0030947; GO:0031625; GO:0031987; GO:0034446; GO:0035426; GO:0035567; GO:0038023; GO:0042701; GO:0042803; GO:0042813; GO:0043507; GO:0044877; GO:0045893; GO:0046982; GO:0050775; GO:0051091; GO:0060070; GO:0061299; GO:0061301; GO:0061304; GO:0071300; GO:0098978; GO:0110135; GO:0150012; GO:1990830 16863 XM_044307873.1 2348 2045 793 2389 2060 Q4PM12 2.21e-31 60S ribosomal protein L36 Ixodes scapularis (Black-legged tick) (Deer tick) translation [GO:0006412] GO:0003735; GO:0005829; GO:0005840; GO:0006412; GO:1990904 16864 XM_029324523.2 169 116 114 247 149 Q9Y3B7 1.38e-44 39S ribosomal protein L11, mitochondrial (L11mt) (MRP-L11) (Mitochondrial large ribosomal subunit protein uL11m) Homo sapiens (Human) mitochondrial translation [GO:0032543]; translation [GO:0006412] GO:0003723; GO:0003735; GO:0005739; GO:0005743; GO:0005761; GO:0005762; GO:0006412; GO:0015934; GO:0032543; GO:0070180 16865 XM_044323033.1 0 49 44 26 0 NA NA NA NA NA NA 16866 XM_029358282.2 33 1 156 0 38 Q21279 7.52e-102 Probable tubulin polyglutamylase ttll-15 (EC 6.-.-.-) (Tubulin--tyrosine ligase-like protein 15) Caenorhabditis elegans oviposition [GO:0018991]; protein modification process [GO:0036211] GO:0005524; GO:0016874; GO:0018991; GO:0036211 16867 XR_003824905.2 0 0 10 0 0 NA NA NA NA NA NA 16868 XR_006396626.1 10 4 121 9 6 NA NA NA NA NA NA 16869 XR_006391898.1 3 9 13 17 81 NA NA NA NA NA NA 16870 XR_006392122.1 0 53 6 0 9 NA NA NA NA NA NA 16871 XM_029349360.2 262 92 220 461 672 O60341 0 Lysine-specific histone demethylase 1A (EC 1.14.99.66) (BRAF35-HDAC complex protein BHC110) (Flavin-containing amine oxidase domain-containing protein 2) ([histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A) Homo sapiens (Human) alternative mRNA splicing, via spliceosome [GO:0000380]; cellular response to cAMP [GO:0071320]; cellular response to gamma radiation [GO:0071480]; cellular response to UV [GO:0034644]; cerebral cortex development [GO:0021987]; DNA repair-dependent chromatin remodeling [GO:0140861]; guanine metabolic process [GO:0046098]; histone H3-K4 demethylation [GO:0034720]; muscle cell development [GO:0055001]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone H3-K9 methylation [GO:0051573]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of protein binding [GO:0032091]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron maturation [GO:0042551]; positive regulation of cell size [GO:0045793]; positive regulation of chromatin binding [GO:0035563]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein demethylation [GO:0006482]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of DNA methylation-dependent heterochromatin formation [GO:0090308]; regulation of double-strand break repair via homologous recombination [GO:0010569]; regulation of protein localization [GO:0032880]; regulation of transcription by RNA polymerase II [GO:0006357]; response to fungicide [GO:0060992] GO:0000122; GO:0000380; GO:0000781; GO:0000785; GO:0002039; GO:0002052; GO:0003682; GO:0005634; GO:0005654; GO:0005667; GO:0006357; GO:0006482; GO:0010569; GO:0010976; GO:0016491; GO:0019899; GO:0021987; GO:0030374; GO:0031398; GO:0032091; GO:0032451; GO:0032452; GO:0032453; GO:0032454; GO:0032880; GO:0032991; GO:0034644; GO:0034720; GO:0035563; GO:0042551; GO:0043392; GO:0043426; GO:0043433; GO:0043518; GO:0045793; GO:0045892; GO:0045944; GO:0046098; GO:0050660; GO:0050681; GO:0051091; GO:0051572; GO:0051573; GO:0055001; GO:0060765; GO:0060992; GO:0061629; GO:0061752; GO:0071320; GO:0071480; GO:0090308; GO:0120162; GO:0140297; GO:0140682; GO:0140861; GO:1902166; GO:1990391; GO:1990841; GO:2000179; GO:2000648 16872 XM_029333603.2 458 0 235 536 565 A0JPI9 1.73e-72 Leucine-rich repeat-containing protein 74A (Leucine-rich repeat-containing protein 74) Rattus norvegicus (Rat) NA NA 16873 XM_044328963.1 5 9 25 8 30 P63018 0 Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) Rattus norvegicus (Rat) aging [GO:0007568]; ATP metabolic process [GO:0046034]; axo-dendritic transport [GO:0008088]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; cerebellum development [GO:0021549]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein folding [GO:0061077]; clathrin coat disassembly [GO:0072318]; estrous cycle [GO:0044849]; forebrain development [GO:0030900]; G1/S transition of mitotic cell cycle [GO:0000082]; kidney development [GO:0001822]; late endosomal microautophagy [GO:0061738]; maintenance of postsynaptic specialization structure [GO:0098880]; modulation by host of viral process [GO:0044788]; mRNA processing [GO:0006397]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of supramolecular fiber organization [GO:1902904]; positive regulation by host of viral genome replication [GO:0044829]; positive regulation of catalytic activity [GO:0043085]; positive regulation of gene expression [GO:0010628]; positive regulation of lysosomal membrane permeability [GO:0097214]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein refolding [GO:1904592]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein autophosphorylation [GO:0046777]; protein folding [GO:0006457]; protein import into nucleus [GO:0006606]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; protein transmembrane import into intracellular organelle [GO:0044743]; protein-containing complex disassembly [GO:0032984]; regulation of cell cycle [GO:0051726]; regulation of postsynapse organization [GO:0099175]; regulation of protein complex stability [GO:0061635]; regulation of protein stability [GO:0031647]; response to activity [GO:0014823]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to nickel cation [GO:0010045]; response to odorant [GO:1990834]; response to progesterone [GO:0032570]; response to starvation [GO:0042594]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; sensory perception of smell [GO:0007608]; skeletal muscle tissue development [GO:0007519]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192] GO:0000082; GO:0000974; GO:0001664; GO:0001786; GO:0001822; GO:0001916; GO:0001917; GO:0003723; GO:0005102; GO:0005524; GO:0005634; GO:0005681; GO:0005730; GO:0005737; GO:0005764; GO:0005765; GO:0005770; GO:0005776; GO:0005829; GO:0005874; GO:0005882; GO:0005886; GO:0006397; GO:0006457; GO:0006606; GO:0007519; GO:0007568; GO:0007608; GO:0008021; GO:0008088; GO:0008380; GO:0009408; GO:0009410; GO:0009986; GO:0010045; GO:0010628; GO:0010667; GO:0014069; GO:0014823; GO:0016191; GO:0016192; GO:0016887; GO:0019899; GO:0021549; GO:0030424; GO:0030425; GO:0030674; GO:0030900; GO:0031072; GO:0031625; GO:0031647; GO:0031686; GO:0032279; GO:0032355; GO:0032570; GO:0032984; GO:0032991; GO:0034605; GO:0034620; GO:0042026; GO:0042277; GO:0042470; GO:0042594; GO:0043005; GO:0043025; GO:0043085; GO:0043195; GO:0043197; GO:0043198; GO:0043202; GO:0043204; GO:0043531; GO:0044183; GO:0044309; GO:0044743; GO:0044788; GO:0044829; GO:0044849; GO:0045121; GO:0045471; GO:0045862; GO:0045892; GO:0046034; GO:0046777; GO:0048026; GO:0048471; GO:0050766; GO:0051082; GO:0051085; GO:0051087; GO:0051726; GO:0051787; GO:0055131; GO:0061077; GO:0061635; GO:0061684; GO:0061738; GO:0061740; GO:0070062; GO:0071276; GO:0072318; GO:0097214; GO:0098684; GO:0098690; GO:0098793; GO:0098794; GO:0098880; GO:0098978; GO:0099175; GO:0099523; GO:0099524; GO:0099634; GO:0101031; GO:0140545; GO:0140662; GO:1902904; GO:1903206; GO:1904592; GO:1904593; GO:1904764; GO:1990124; GO:1990832; GO:1990833; GO:1990834; GO:1990836; GO:1990904 16874 XM_029335217.2 124 40 73 11 198 Q61382 1.56e-25 TNF receptor-associated factor 4 (EC 2.3.2.27) (Cysteine-rich motif associated to RING and Traf domains protein 1) Mus musculus (Mouse) activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; innate immune response [GO:0045087]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein kinase activity [GO:0045860]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; respiratory gaseous exchange by respiratory system [GO:0007585]; respiratory tube development [GO:0030323] GO:0001650; GO:0005164; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0005923; GO:0006915; GO:0007250; GO:0007585; GO:0008270; GO:0016740; GO:0019901; GO:0030323; GO:0031625; GO:0031996; GO:0042802; GO:0042981; GO:0043122; GO:0043161; GO:0045087; GO:0045860; GO:0046330; GO:0048471; GO:0050699 16875 XM_029342351.2 810 827 381 820 490 NA NA NA NA NA NA 16876 XM_044323080.1 65 0 137 43 469 NA NA NA NA NA NA 16877 XR_003826622.2 498 352 406 394 505 NA NA NA NA NA NA 16878 XM_029335373.2 2904 3828 2487 2701 2295 Q93104 3.66e-46 Enhancer of rudimentary homolog Aedes aegypti (Yellowfever mosquito) (Culex aegypti) cell cycle [GO:0007049] GO:0007049 16879 XM_044319472.1 9 29 16 107 231 P46825 5.76e-28 Kinesin light chain (KLC) Doryteuthis pealeii (Longfin inshore squid) (Loligo pealeii) NA GO:0005737; GO:0005871; GO:0005874 16880 XR_006393366.1 0 0 32 4 0 NA NA NA NA NA NA 16881 XM_044325653.1 35 12 0 32 120 NA NA NA NA NA NA 16882 XM_044322790.1 0 0 0 0 26 NA NA NA NA NA NA 16883 XR_006396372.1 5646 3122 1911 2506 1666 NA NA NA NA NA NA 16884 XM_044314214.1 0 0 0 0 8 NA NA NA NA NA NA 16885 XM_044319795.1 438 306 235 521 774 Q8TEX9 0 Importin-4 (Imp4) (Importin-4b) (Imp4b) (Ran-binding protein 4) (RanBP4) Homo sapiens (Human) protein import into nucleus [GO:0006606]; protein localization to nucleus [GO:0034504] GO:0000785; GO:0005634; GO:0005737; GO:0006606; GO:0008139; GO:0016020; GO:0031267; GO:0032991; GO:0034504; GO:0061608 16886 XM_044327935.1 87 87 13 363 820 NA NA NA NA NA NA 16887 XM_029338723.2 319 138 92 202 208 NA NA NA NA NA NA 16888 XM_044308132.1 9 10 5 27 47 NA NA NA NA NA NA 16889 XM_029331099.2 488 93 158 399 370 Q8CFX1 0 GDH/6PGL endoplasmic bifunctional protein [Includes: Hexose-6-phosphate dehydrogenase (Glucose 1-dehydrogenase) (EC 1.1.1.47) (Glucose-6-phosphate dehydrogenase) (EC 1.1.1.363); 6-phosphogluconolactonase (6PGL) (EC 3.1.1.31)] Mus musculus (Mouse) carbohydrate metabolic process [GO:0005975]; glucose metabolic process [GO:0006006]; NADP metabolic process [GO:0006739]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, oxidative branch [GO:0009051]; regulation of cortisol biosynthetic process [GO:2000064] GO:0004345; GO:0005737; GO:0005739; GO:0005783; GO:0005788; GO:0005975; GO:0006006; GO:0006098; GO:0006739; GO:0009051; GO:0016529; GO:0017057; GO:0030246; GO:0043231; GO:0047934; GO:0047935; GO:0047936; GO:0050661; GO:2000064 16890 XM_044317703.1 250 288 202 334 318 Q9HC77 8.06e-33 Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1) Homo sapiens (Human) astral microtubule nucleation [GO:0030954]; cell division [GO:0051301]; centriole elongation [GO:0061511]; centriole replication [GO:0007099]; cilium assembly [GO:0060271]; microtubule nucleation [GO:0007020]; microtubule polymerization [GO:0046785]; motile cilium assembly [GO:0044458]; non-motile cilium assembly [GO:1905515]; positive regulation of centriole elongation [GO:1903724]; positive regulation of centriole replication [GO:0046601]; positive regulation of establishment of protein localization [GO:1904951]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of non-motile cilium assembly [GO:1902857]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of spindle assembly [GO:1905832]; regulation of centriole replication [GO:0046599]; regulation of mitotic spindle organization [GO:0060236]; smoothened signaling pathway [GO:0007224] GO:0003713; GO:0005634; GO:0005737; GO:0005813; GO:0005814; GO:0005829; GO:0005874; GO:0007020; GO:0007099; GO:0007224; GO:0008275; GO:0015631; GO:0019901; GO:0019904; GO:0030954; GO:0036064; GO:0042802; GO:0043015; GO:0044458; GO:0046427; GO:0046599; GO:0046601; GO:0046785; GO:0051301; GO:0060236; GO:0060271; GO:0061511; GO:0120099; GO:1900087; GO:1902857; GO:1903724; GO:1904951; GO:1905515; GO:1905832 16891 XM_029347880.2 8465 6818 4182 6687 5878 P49596 9.37e-137 Probable protein phosphatase 2C T23F11.1 (PP2C) (EC 3.1.3.16) Caenorhabditis elegans negative regulation of axon extension [GO:0030517]; positive regulation of synapse assembly [GO:0051965]; protein dephosphorylation [GO:0006470] GO:0006470; GO:0017018; GO:0030517; GO:0031625; GO:0046872; GO:0048786; GO:0051965 16892 XR_003825762.2 0 28 0 29 17 NA NA NA NA NA NA 16893 XM_029346359.2 59 93 90 118 146 NA NA NA NA NA NA 16894 XM_029352394.2 1801 1937 1642 2048 2780 A7RSH7 2.11e-31 Eukaryotic translation initiation factor 3 subunit J (eIF3j) Nematostella vectensis (Starlet sea anemone) formation of cytoplasmic translation initiation complex [GO:0001732] GO:0001732; GO:0003743; GO:0005852; GO:0016282; GO:0033290 16895 XM_044315536.1 169 49 61 0 1 NA NA NA NA NA NA 16896 XM_044318487.1 1144 1591 654 575 805 NA NA NA NA NA NA 16897 XM_044313261.1 291 264 3 0 83 A2AP18 0 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-eta-2) (Phosphoinositide phospholipase C-like 4) (PLC-L4) (Phospholipase C-like protein 4) (Phospholipase C-eta-2) (PLC-eta2) Mus musculus (Mouse) lipid catabolic process [GO:0016042]; phosphatidylinositol metabolic process [GO:0046488]; phosphatidylinositol-mediated signaling [GO:0048015] GO:0004435; GO:0004629; GO:0005509; GO:0005737; GO:0005886; GO:0016042; GO:0046488; GO:0048015 16898 XM_044309286.1 199 29 69 78 262 NA NA NA NA NA NA 16899 XM_029339893.2 103 0 227 168 943 A2VE56 3.85e-32 PHD finger protein 20-like protein 1 Bos taurus (Bovine) histone acetylation [GO:0016573]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0005634; GO:0006357; GO:0016573; GO:0044545 16900 XM_044308373.1 1824 1579 1074 1664 1801 A0JPE9 3.73e-170 Putative glycerol kinase 5 (GK 5) (Glycerokinase 5) (EC 2.7.1.30) (ATP:glycerol 3-phosphotransferase 5) Danio rerio (Zebrafish) (Brachydanio rerio) glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate biosynthetic process [GO:0046167]; phosphorylation [GO:0016310]; triglyceride metabolic process [GO:0006641] GO:0004370; GO:0005524; GO:0005739; GO:0006071; GO:0006641; GO:0016310; GO:0019563; GO:0046167 16901 XR_006392459.1 217 147 47 140 106 NA NA NA NA NA NA 16902 XM_029336673.2 254 106 121 172 261 Q5VXM1 2.84e-23 CUB domain-containing protein 2 Homo sapiens (Human) NA GO:0005576 16903 XM_044326775.1 201 148 183 163 312 NA NA NA NA NA NA 16904 XM_029331859.2 259 137 170 155 222 A1L2T6 4.07e-32 Zinc finger CCHC domain-containing protein 7 (TRAMP-like complex RNA-binding factor ZCCHC7) Xenopus laevis (African clawed frog) NA GO:0003676; GO:0005730; GO:0008270 16905 XM_029339864.2 49 6 2 16 24 NA NA NA NA NA NA 16906 XM_044324917.1 87 46 75 0 208 Q9UQ26 2.29e-63 Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2) (Rab-3-interacting protein 3) Homo sapiens (Human) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-ion regulated exocytosis [GO:0017156]; cell differentiation [GO:0030154]; insulin secretion [GO:0030073]; intracellular protein transport [GO:0006886]; positive regulation of dendrite extension [GO:1903861]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of synaptic transmission [GO:0050806]; regulation of exocytosis [GO:0017157]; regulation of membrane potential [GO:0042391]; regulation of synaptic plasticity [GO:0048167]; spontaneous neurotransmitter secretion [GO:0061669] GO:0006886; GO:0007188; GO:0017156; GO:0017157; GO:0030073; GO:0030154; GO:0031267; GO:0042391; GO:0042734; GO:0042995; GO:0044325; GO:0046872; GO:0048167; GO:0048786; GO:0048788; GO:0048791; GO:0050806; GO:0061669; GO:0070062; GO:0097151; GO:1903861; GO:2000463 16907 XM_044324917.1 87 46 75 0 208 Q9UQ26 1.36e-30 Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2) (Rab-3-interacting protein 3) Homo sapiens (Human) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-ion regulated exocytosis [GO:0017156]; cell differentiation [GO:0030154]; insulin secretion [GO:0030073]; intracellular protein transport [GO:0006886]; positive regulation of dendrite extension [GO:1903861]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of synaptic transmission [GO:0050806]; regulation of exocytosis [GO:0017157]; regulation of membrane potential [GO:0042391]; regulation of synaptic plasticity [GO:0048167]; spontaneous neurotransmitter secretion [GO:0061669] GO:0006886; GO:0007188; GO:0017156; GO:0017157; GO:0030073; GO:0030154; GO:0031267; GO:0042391; GO:0042734; GO:0042995; GO:0044325; GO:0046872; GO:0048167; GO:0048786; GO:0048788; GO:0048791; GO:0050806; GO:0061669; GO:0070062; GO:0097151; GO:1903861; GO:2000463 16908 XM_029349419.2 10298 8256 4368 7549 6329 P21251 9.23e-54 Calmodulin (CaM) Stichopus japonicus (Sea cucumber) NA GO:0005509 16909 XM_029349419.2 10298 8256 4368 7549 6329 P21251 7.97e-41 Calmodulin (CaM) Stichopus japonicus (Sea cucumber) NA GO:0005509 16910 XM_029349419.2 10298 8256 4368 7549 6329 P21251 4.5e-28 Calmodulin (CaM) Stichopus japonicus (Sea cucumber) NA GO:0005509 16911 XR_006397996.1 49 0 34 0 0 NA NA NA NA NA NA 16912 XR_006396108.1 0 0 78 0 0 NA NA NA NA NA NA 16913 XM_044324671.1 24 0 24 0 0 Q3UES3 9.12e-21 Poly [ADP-ribose] polymerase tankyrase-2 (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 6) (ARTD6) (Protein poly-ADP-ribosyltransferase tankyrase-2) (EC 2.4.2.-) (TNKS-2) (TRF1-interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase II) (Tankyrase-2) (TANK2) Mus musculus (Mouse) multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomere capping [GO:1904355]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; regulation of multicellular organism growth [GO:0040014]; telomere maintenance [GO:0000723]; Wnt signaling pathway [GO:0016055] GO:0000139; GO:0000209; GO:0000242; GO:0000723; GO:0000781; GO:0003950; GO:0005634; GO:0005635; GO:0005737; GO:0016055; GO:0016779; GO:0019899; GO:0035264; GO:0040014; GO:0046872; GO:0047485; GO:0048471; GO:0070198; GO:0070212; GO:0070213; GO:0090263; GO:1904355; GO:1904357; GO:1990404 16914 XM_044328822.1 8 1 0 0 0 NA NA NA NA NA NA 16915 XM_044310069.1 3 2 0 9 3 Q09575 1.72e-37 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 16916 XM_029354354.2 432 689 478 1294 1616 Q12986 0 Transcriptional repressor NF-X1 (EC 2.3.2.-) (Nuclear transcription factor, X box-binding protein 1) Homo sapiens (Human) inflammatory response [GO:0006954]; negative regulation of MHC class II biosynthetic process [GO:0045347]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein autoubiquitination [GO:0051865]; protein ubiquitination [GO:0016567]; regulation of DNA-templated transcription [GO:0006355]; transcription by RNA polymerase II [GO:0006366] GO:0000122; GO:0000785; GO:0000977; GO:0000981; GO:0001227; GO:0003723; GO:0005634; GO:0005654; GO:0005730; GO:0005829; GO:0005886; GO:0006355; GO:0006366; GO:0006954; GO:0008270; GO:0016567; GO:0045347; GO:0051865; GO:0061630 16917 XM_044319052.1 13 5 9 5 17 Q96DM1 1.56e-32 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 16918 XM_029353042.2 8 21 1 26 2 F1R332 1.12e-24 Galanin receptor 2a Danio rerio (Zebrafish) (Brachydanio rerio) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; neuropeptide signaling pathway [GO:0007218] GO:0004966; GO:0005886; GO:0007188; GO:0007218; GO:0008528 16919 XM_029335908.2 84 69 25 9 31 Q05B50 3.85e-65 Probable tRNA(His) guanylyltransferase (EC 2.7.7.79) (tRNA-histidine guanylyltransferase) Bos taurus (Bovine) protein homotetramerization [GO:0051289]; response to oxidative stress [GO:0006979]; stress-induced mitochondrial fusion [GO:1990046]; tRNA modification [GO:0006400]; tRNA processing [GO:0008033] GO:0000287; GO:0005085; GO:0005524; GO:0005525; GO:0005739; GO:0006400; GO:0006979; GO:0008033; GO:0008193; GO:0042802; GO:0051289; GO:1990046; GO:1990234 16920 XM_029328989.2 4 0 0 10 16 NA NA NA NA NA NA 16921 XM_029343940.2 0 52 44 48 0 NA NA NA NA NA NA 16922 XR_006396735.1 0 29 0 0 0 NA NA NA NA NA NA 16923 XM_029326878.2 0 0 102 315 123 Q86UW6 1.93e-49 NEDD4-binding protein 2 (N4BP2) (EC 3.-.-.-) (BCL-3-binding protein) Homo sapiens (Human) NA GO:0004519; GO:0004520; GO:0005524; GO:0005829; GO:0043130; GO:0046404 16924 XM_029326878.2 0 0 102 315 123 Q86UW6 4.29e-39 NEDD4-binding protein 2 (N4BP2) (EC 3.-.-.-) (BCL-3-binding protein) Homo sapiens (Human) NA GO:0004519; GO:0004520; GO:0005524; GO:0005829; GO:0043130; GO:0046404 16925 XM_044311532.1 35 33 26 11 266 Q9TXJ8 1.39e-37 Putative ATP-dependent DNA helicase Q1 (EC 3.6.4.12) Caenorhabditis elegans DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724] GO:0000724; GO:0003676; GO:0005524; GO:0005634; GO:0005694; GO:0005737; GO:0006268; GO:0006281; GO:0006310; GO:0009378; GO:0016887; GO:0032508; GO:0043138 16926 XM_029327254.2 314 204 251 94 393 B0S5Y3 7.9e-89 Solute carrier family 52, riboflavin transporter, member 3-A (Riboflavin transporter 2-A) (RFT2-A) Danio rerio (Zebrafish) (Brachydanio rerio) riboflavin transport [GO:0032218] GO:0005886; GO:0032217; GO:0032218 16927 XM_029343242.2 1553 1288 580 1092 1011 P53992 0 Protein transport protein Sec24C (SEC24-related protein C) Homo sapiens (Human) COPII-coated vesicle cargo loading [GO:0090110]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; in utero embryonic development [GO:0001701]; intracellular protein transport [GO:0006886] GO:0000149; GO:0001701; GO:0005789; GO:0005829; GO:0006886; GO:0006888; GO:0008270; GO:0012507; GO:0030127; GO:0070971; GO:0090110 16928 XM_044314152.1 299 246 236 225 320 Q63055 5.53e-81 ADP-ribosylation factor-related protein 1 (ARF-related protein 1) (ARP) Rattus norvegicus (Rat) gastrulation [GO:0007369]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; protein localization to Golgi apparatus [GO:0034067]; retrograde transport, endosome to Golgi [GO:0042147] GO:0003924; GO:0005525; GO:0005794; GO:0005802; GO:0005829; GO:0006886; GO:0007369; GO:0016020; GO:0034067; GO:0042147; GO:0043001 16929 XM_044322694.1 137 116 202 119 95 A2AV25 2.28e-59 Fibrinogen C domain-containing protein 1 Mus musculus (Mouse) cell adhesion [GO:0007155] GO:0005102; GO:0005615; GO:0007155; GO:0008061; GO:0016020; GO:0046872; GO:0062023 16930 XM_044322694.1 137 116 202 119 95 A2AV25 2.67e-56 Fibrinogen C domain-containing protein 1 Mus musculus (Mouse) cell adhesion [GO:0007155] GO:0005102; GO:0005615; GO:0007155; GO:0008061; GO:0016020; GO:0046872; GO:0062023 16931 XM_044315705.1 0 0 171 2 0 NA NA NA NA NA NA 16932 XR_006391497.1 0 0 0 0 6 NA NA NA NA NA NA 16933 XM_044310894.1 66 8 23 42 27 Q3UQ28 6.2e-30 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 16934 XM_044310894.1 66 8 23 42 27 Q3UQ28 4.99e-28 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 16935 XM_044310894.1 66 8 23 42 27 Q3UQ28 7.64e-27 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 16936 XM_044310894.1 66 8 23 42 27 Q3UQ28 8.39e-26 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 16937 XR_006395688.1 83 126 127 105 80 NA NA NA NA NA NA 16938 XR_006396233.1 233 11 61 114 63 NA NA NA NA NA NA 16939 XM_044314008.1 9 7 0 0 5 NA NA NA NA NA NA 16940 XM_044314105.1 63 24 40 47 40 Q80XJ3 2.13e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 16941 XM_029348146.2 363 249 219 347 390 Q8CI75 0 DIS3-like exonuclease 2 (EC 3.1.13.-) Mus musculus (Mouse) cell division [GO:0051301]; miRNA catabolic process [GO:0010587]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid separation [GO:0051306]; mRNA catabolic process [GO:0006402]; negative regulation of cell population proliferation [GO:0008285]; nuclear-transcribed mRNA catabolic process, exonucleolytic [GO:0000291]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; polyuridylation-dependent mRNA catabolic process [GO:1990074]; stem cell population maintenance [GO:0019827] GO:0000175; GO:0000178; GO:0000278; GO:0000287; GO:0000291; GO:0000932; GO:0004540; GO:0005737; GO:0006402; GO:0008266; GO:0008285; GO:0010587; GO:0019827; GO:0034427; GO:0051301; GO:0051306; GO:1990074 16942 XM_044319762.1 637 132 206 211 103 Q6J2U6 9.79e-57 E3 ubiquitin-protein ligase RNF114 (EC 2.3.2.27) (RING finger protein 114) (RING-type E3 ubiquitin transferase RNF114) (Zinc finger protein 313) Rattus norvegicus (Rat) cell differentiation [GO:0030154]; protein polyubiquitination [GO:0000209]; spermatogenesis [GO:0007283]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000209; GO:0005634; GO:0005737; GO:0006511; GO:0007283; GO:0030154; GO:0046872; GO:0061630 16943 XM_029345890.2 82 128 171 143 216 NA NA NA NA NA NA 16944 XM_029331092.2 6 10 0 0 0 A7SEP9 2.07e-33 U1 small nuclear ribonucleoprotein C (U1 snRNP C) (U1-C) (U1C) Nematostella vectensis (Starlet sea anemone) mRNA 5'-splice site recognition [GO:0000395]; spliceosomal snRNP assembly [GO:0000387] GO:0000243; GO:0000387; GO:0000395; GO:0003729; GO:0005685; GO:0008270; GO:0030619; GO:0030627; GO:0071004 16945 XR_006396710.1 0 3 0 0 9 NA NA NA NA NA NA 16946 XM_044317786.1 1190 1254 753 1007 1424 P55809 0 Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial (SCOT) (EC 2.8.3.5) (3-oxoacid CoA-transferase 1) (Somatic-type succinyl-CoA:3-oxoacid CoA-transferase) (SCOT-s) (Succinyl-CoA:3-oxoacid CoA transferase) Homo sapiens (Human) adipose tissue development [GO:0060612]; brain development [GO:0007420]; cellular ketone body metabolic process [GO:0046950]; heart development [GO:0007507]; ketone body catabolic process [GO:0046952]; ketone catabolic process [GO:0042182]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; response to activity [GO:0014823]; response to ethanol [GO:0045471]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; response to starvation [GO:0042594]; response to xenobiotic stimulus [GO:0009410] GO:0005739; GO:0005759; GO:0007420; GO:0007507; GO:0007584; GO:0008260; GO:0008410; GO:0009410; GO:0009725; GO:0014823; GO:0035774; GO:0042182; GO:0042594; GO:0042802; GO:0045471; GO:0046950; GO:0046952; GO:0060612 16947 XM_044317786.1 1190 1254 753 1007 1424 P55809 1.06e-26 Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial (SCOT) (EC 2.8.3.5) (3-oxoacid CoA-transferase 1) (Somatic-type succinyl-CoA:3-oxoacid CoA-transferase) (SCOT-s) (Succinyl-CoA:3-oxoacid CoA transferase) Homo sapiens (Human) adipose tissue development [GO:0060612]; brain development [GO:0007420]; cellular ketone body metabolic process [GO:0046950]; heart development [GO:0007507]; ketone body catabolic process [GO:0046952]; ketone catabolic process [GO:0042182]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; response to activity [GO:0014823]; response to ethanol [GO:0045471]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; response to starvation [GO:0042594]; response to xenobiotic stimulus [GO:0009410] GO:0005739; GO:0005759; GO:0007420; GO:0007507; GO:0007584; GO:0008260; GO:0008410; GO:0009410; GO:0009725; GO:0014823; GO:0035774; GO:0042182; GO:0042594; GO:0042802; GO:0045471; GO:0046950; GO:0046952; GO:0060612 16948 XM_029336504.2 77 22 66 65 98 NA NA NA NA NA NA 16949 XM_029324870.2 48 0 168 0 185 Q14671 0 Pumilio homolog 1 (HsPUM) (Pumilio-1) Homo sapiens (Human) adult locomotory behavior [GO:0008344]; miRNA processing [GO:0035196]; mRNA destabilization [GO:0061157]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; positive regulation of RIG-I signaling pathway [GO:1900246]; post-transcriptional gene silencing [GO:0016441]; post-transcriptional regulation of gene expression [GO:0010608]; regulation of cell cycle [GO:0051726]; regulation of chromosome segregation [GO:0051983]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of mRNA stability [GO:0043488]; spermatogenesis [GO:0007283]; stem cell differentiation [GO:0048863] GO:0000932; GO:0003723; GO:0003729; GO:0003730; GO:0005654; GO:0005737; GO:0005829; GO:0007283; GO:0008344; GO:0010494; GO:0010608; GO:0016441; GO:0035196; GO:0035198; GO:0043488; GO:0048863; GO:0051726; GO:0051983; GO:0060964; GO:0061157; GO:1900246; GO:2000637 16950 XM_029324870.2 48 0 168 0 185 Q14671 3.08e-27 Pumilio homolog 1 (HsPUM) (Pumilio-1) Homo sapiens (Human) adult locomotory behavior [GO:0008344]; miRNA processing [GO:0035196]; mRNA destabilization [GO:0061157]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; positive regulation of RIG-I signaling pathway [GO:1900246]; post-transcriptional gene silencing [GO:0016441]; post-transcriptional regulation of gene expression [GO:0010608]; regulation of cell cycle [GO:0051726]; regulation of chromosome segregation [GO:0051983]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of mRNA stability [GO:0043488]; spermatogenesis [GO:0007283]; stem cell differentiation [GO:0048863] GO:0000932; GO:0003723; GO:0003729; GO:0003730; GO:0005654; GO:0005737; GO:0005829; GO:0007283; GO:0008344; GO:0010494; GO:0010608; GO:0016441; GO:0035196; GO:0035198; GO:0043488; GO:0048863; GO:0051726; GO:0051983; GO:0060964; GO:0061157; GO:1900246; GO:2000637 16951 XM_029345207.2 74 49 33 39 51 NA NA NA NA NA NA 16952 XM_029346195.2 25 0 0 0 0 Q9I8C7 8.36e-89 Neuronal acetylcholine receptor subunit alpha-10 (Alpha 10 nAChR) (Nicotinic acetylcholine receptor subunit alpha-10) (NACHR alpha-10) Gallus gallus (Chicken) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; response to auditory stimulus [GO:0010996]; signal transduction [GO:0007165] GO:0004888; GO:0005231; GO:0005262; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0010996; GO:0022848; GO:0030594; GO:0034220; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051899; GO:1904315 16953 XM_029347180.2 15 36 7 61 49 A4QNG3 6.27e-25 Transcription factor Sox-14 (SRY (sex determining region Y)-box 14) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399] GO:0000122; GO:0005634; GO:0007399; GO:0043565; GO:0045892 16954 XM_029328144.2 27 14 40 64 74 NA NA NA NA NA NA 16955 XM_044328790.1 6 0 0 0 0 Q86WA9 3.19e-48 Sodium-independent sulfate anion transporter (Solute carrier family 26 member 11) Homo sapiens (Human) ion transport [GO:0006811]; sulfate transport [GO:0008272] GO:0005654; GO:0005765; GO:0005783; GO:0005794; GO:0005886; GO:0006811; GO:0008271; GO:0008272; GO:0008509; GO:0015116; GO:0016020; GO:0043231; GO:0070062 16956 XM_044320392.1 16 11 14 70 57 NA NA NA NA NA NA 16957 XR_006393628.1 65 28 160 0 348 NA NA NA NA NA NA 16958 XM_029344691.2 158 255 0 218 128 Q9Y4D2 1.58e-143 Diacylglycerol lipase-alpha (DAGL-alpha) (DGL-alpha) (EC 3.1.1.116) (Neural stem cell-derived dendrite regulator) (Sn1-specific diacylglycerol lipase alpha) Homo sapiens (Human) arachidonic acid metabolic process [GO:0019369]; diacylglycerol catabolic process [GO:0046340]; endocannabinoid signaling pathway [GO:0071926]; G protein-coupled glutamate receptor signaling pathway [GO:0007216]; lipid catabolic process [GO:0016042]; neuroblast proliferation [GO:0007405]; neurogenesis [GO:0022008]; neurotransmitter biosynthetic process [GO:0042136]; regulation of neuroinflammatory response [GO:0150077]; retrograde trans-synaptic signaling by endocannabinoid [GO:0098921] GO:0004465; GO:0004806; GO:0005737; GO:0005886; GO:0007216; GO:0007405; GO:0016042; GO:0016298; GO:0019369; GO:0022008; GO:0031901; GO:0032590; GO:0032591; GO:0042136; GO:0043196; GO:0045211; GO:0046340; GO:0046872; GO:0047372; GO:0071926; GO:0098839; GO:0098921; GO:0150077 16959 XM_044326237.1 11 2 0 6 17 NA NA NA NA NA NA 16960 XM_044309548.1 48 2 17 21 7 NA NA NA NA NA NA 16961 XR_006393236.1 5 31 4 0 6 NA NA NA NA NA NA 16962 XM_044306915.1 0 12 30 48 23 NA NA NA NA NA NA 16963 XM_044311856.1 270 78 126 129 371 A1L3G4 4e-28 Transmembrane protein 241 Xenopus laevis (African clawed frog) NA GO:0016020 16964 XM_029334463.2 0 208 0 0 0 P54366 1.28e-31 Homeobox protein goosecoid Drosophila melanogaster (Fruit fly) negative regulation of DNA-templated transcription [GO:0045892]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000977; GO:0000981; GO:0001227; GO:0005634; GO:0006357; GO:0042803; GO:0045892; GO:0046982 16965 XM_029327158.2 74 225 75 178 171 Q9CYL5 3.28e-26 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Mus musculus (Mouse) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070374 16966 XM_029323412.2 1182 1183 936 1176 1058 Q96EZ8 2.78e-134 Microspherule protein 1 (58 kDa microspherule protein) (Cell cycle-regulated factor p78) (INO80 complex subunit J) (MCRS2) Homo sapiens (Human) chromatin remodeling [GO:0006338]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of protein localization to nucleolus [GO:1904751]; positive regulation of telomere maintenance in response to DNA damage [GO:1904507]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein modification process [GO:0036211]; regulation of cell cycle [GO:0051726]; regulation of chromosome organization [GO:0033044]; regulation of DNA repair [GO:0006282]; regulation of DNA replication [GO:0006275]; regulation of DNA strand elongation [GO:0060382]; regulation of dosage compensation by inactivation of X chromosome [GO:1900095]; regulation of embryonic development [GO:0045995]; telomere maintenance [GO:0000723] GO:0000123; GO:0000723; GO:0002151; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005783; GO:0005844; GO:0006275; GO:0006281; GO:0006282; GO:0006310; GO:0006338; GO:0008266; GO:0010521; GO:0030425; GO:0031011; GO:0033044; GO:0034046; GO:0036211; GO:0043204; GO:0043981; GO:0043982; GO:0043984; GO:0044545; GO:0045739; GO:0045893; GO:0045944; GO:0045995; GO:0051571; GO:0051726; GO:0051974; GO:0060382; GO:0071339; GO:1900095; GO:1904357; GO:1904507; GO:1904751 16967 XM_044320345.1 1884 1322 1039 2085 1820 P22607 3.23e-99 Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333) Homo sapiens (Human) bone maturation [GO:0070977]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cell-cell signaling [GO:0007267]; chondrocyte differentiation [GO:0002062]; chondrocyte proliferation [GO:0035988]; endochondral bone growth [GO:0003416]; endochondral ossification [GO:0001958]; fibroblast growth factor receptor apoptotic signaling pathway [GO:1902178]; fibroblast growth factor receptor signaling pathway [GO:0008543]; MAPK cascade [GO:0000165]; negative regulation of developmental growth [GO:0048640]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein autophosphorylation [GO:0046777]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0000165; GO:0001501; GO:0001958; GO:0002062; GO:0003416; GO:0004713; GO:0004714; GO:0005007; GO:0005524; GO:0005576; GO:0005634; GO:0005783; GO:0005794; GO:0005886; GO:0007169; GO:0007267; GO:0008284; GO:0008543; GO:0009986; GO:0010518; GO:0017134; GO:0018108; GO:0030133; GO:0030282; GO:0033674; GO:0035988; GO:0042531; GO:0042802; GO:0043235; GO:0043410; GO:0043552; GO:0046777; GO:0048640; GO:0060349; GO:0070374; GO:0070977; GO:1902178 16968 XM_044312700.1 143 43 27 41 76 NA NA NA NA NA NA 16969 XM_029330488.2 820 716 428 651 550 Q9H7P6 4.78e-24 Multivesicular body subunit 12B (ESCRT-I complex subunit MVB12B) (Protein FAM125B) Homo sapiens (Human) membrane fission [GO:0090148]; multivesicular body assembly [GO:0036258]; protein transport [GO:0015031]; protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; viral budding [GO:0046755]; virus maturation [GO:0019075] GO:0000813; GO:0005634; GO:0005769; GO:0005770; GO:0005829; GO:0005886; GO:0008289; GO:0010008; GO:0015031; GO:0019075; GO:0031902; GO:0031982; GO:0036258; GO:0042058; GO:0043162; GO:0043328; GO:0046755; GO:0070062; GO:0090148 16970 XR_006397946.1 211 56 52 150 138 NA NA NA NA NA NA 16971 XM_029342846.2 405 367 680 442 149 P16444 9.55e-128 Dipeptidase 1 (EC 3.4.13.19) (Beta-lactamase) (EC 3.5.2.6) (Dehydropeptidase-I) (Microsomal dipeptidase) (Renal dipeptidase) (hRDP) Homo sapiens (Human) antibiotic metabolic process [GO:0016999]; cellular response to calcium ion [GO:0071277]; cellular response to nitric oxide [GO:0071732]; cellular response to xenobiotic stimulus [GO:0071466]; glutathione catabolic process [GO:0006751]; glutathione metabolic process [GO:0006749]; homocysteine metabolic process [GO:0050667]; inflammatory response [GO:0006954]; lactam catabolic process [GO:0072340]; leukotriene D4 catabolic process [GO:1901749]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell migration [GO:0030336]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; neutrophil chemotaxis [GO:0030593]; proteolysis [GO:0006508] GO:0005615; GO:0005654; GO:0005886; GO:0006508; GO:0006749; GO:0006751; GO:0006954; GO:0008235; GO:0008270; GO:0008800; GO:0016324; GO:0016805; GO:0016999; GO:0030054; GO:0030336; GO:0030593; GO:0031528; GO:0034235; GO:0043027; GO:0043066; GO:0043154; GO:0045177; GO:0050667; GO:0070062; GO:0070573; GO:0071277; GO:0071466; GO:0071732; GO:0072340; GO:0072341; GO:1901749 16972 XM_029323419.2 3130 2231 1811 2475 2469 P35991 2.61e-177 Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell progenitor kinase) (BPK) (Bruton tyrosine kinase) (Kinase EMB) Mus musculus (Mouse) apoptotic process [GO:0006915]; B cell affinity maturation [GO:0002344]; B cell receptor signaling pathway [GO:0050853]; cell maturation [GO:0048469]; cellular response to interleukin-7 [GO:0098761]; cellular response to molecule of fungal origin [GO:0071226]; cellular response to reactive oxygen species [GO:0034614]; eosinophil homeostasis [GO:1990959]; histamine secretion by mast cell [GO:0002553]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; monocyte proliferation [GO:0061516]; negative regulation of B cell activation [GO:0050869]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cytokine production [GO:0001818]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of leukocyte proliferation [GO:0070664]; neutrophil homeostasis [GO:0001780]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-17A production [GO:0150153]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of NLRP3 inflammasome complex assembly [GO:1900227]; positive regulation of phagocytosis [GO:0050766]; positive regulation of synoviocyte proliferation [GO:1901647]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type III hypersensitivity [GO:0001805]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; proteoglycan catabolic process [GO:0030167]; response to lipopolysaccharide [GO:0032496]; response to organic substance [GO:0010033] GO:0001780; GO:0001805; GO:0001812; GO:0001818; GO:0002344; GO:0002553; GO:0002639; GO:0004713; GO:0004715; GO:0005524; GO:0005547; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0006468; GO:0006915; GO:0007249; GO:0010033; GO:0016004; GO:0018108; GO:0030167; GO:0030889; GO:0030890; GO:0031410; GO:0032496; GO:0032693; GO:0032755; GO:0032760; GO:0034614; GO:0035556; GO:0038083; GO:0042802; GO:0043274; GO:0045087; GO:0045121; GO:0046777; GO:0046872; GO:0048469; GO:0048471; GO:0050729; GO:0050766; GO:0050853; GO:0050869; GO:0061516; GO:0070664; GO:0071226; GO:0098761; GO:0150153; GO:1900227; GO:1901647; GO:1990959 16973 XM_029339731.2 154 172 155 209 256 Q6GLQ4 1.17e-25 Serine/threonine-protein phosphatase 1 regulatory subunit 10 Xenopus laevis (African clawed frog) NA GO:0004864; GO:0005634; GO:0046872 16974 XM_029339731.2 154 172 155 209 256 Q6GLQ4 2.57e-25 Serine/threonine-protein phosphatase 1 regulatory subunit 10 Xenopus laevis (African clawed frog) NA GO:0004864; GO:0005634; GO:0046872 16975 XM_029333298.2 0 122 330 11 2732 Q96AY4 3.79e-138 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16976 XM_029333298.2 0 122 330 11 2732 Q96AY4 4.27e-130 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16977 XM_029333298.2 0 122 330 11 2732 Q96AY4 9.1e-107 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16978 XM_029333298.2 0 122 330 11 2732 Q96AY4 1.21e-69 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16979 XM_029333298.2 0 122 330 11 2732 Q96AY4 1.23e-37 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16980 XM_029333298.2 0 122 330 11 2732 Q96AY4 6.55e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16981 XM_044321464.1 822 466 498 643 920 Q60649 0 Caseinolytic peptidase B protein homolog (EC 3.6.1.-) (Suppressor of potassium transport defect 3) Mus musculus (Mouse) antiviral innate immune response [GO:0140374]; cellular response to heat [GO:0034605]; granulocyte differentiation [GO:0030851]; RIG-I signaling pathway [GO:0039529] GO:0005524; GO:0005737; GO:0005739; GO:0005758; GO:0016887; GO:0030851; GO:0034605; GO:0039529; GO:0140374; GO:0140545 16982 XM_029335507.2 166 180 46 95 63 P83852 1.61e-150 Carboxypeptidase D (EC 3.4.17.22) (CPD-2) (Metallocarboxypeptidase D) Lophonetta specularioides (Crested duck) (Anas specularioides) proteolysis [GO:0006508] GO:0004181; GO:0006508; GO:0008270; GO:0016020 16983 XM_029338466.2 16595 19166 11731 13680 8132 A1DPK7 1.64e-88 Actin-related protein 2/3 complex subunit 3-A Xenopus laevis (African clawed frog) Arp2/3 complex-mediated actin nucleation [GO:0034314]; regulation of actin filament polymerization [GO:0030833] GO:0003779; GO:0005634; GO:0005737; GO:0005885; GO:0030833; GO:0034314; GO:0035861; GO:0042995 16984 XM_029349293.2 7 2 0 0 17 NA NA NA NA NA NA 16985 XR_006394373.1 7 0 33 36 30 NA NA NA NA NA NA 16986 XM_044314677.1 16 14 2 33 2 NA NA NA NA NA NA 16987 XM_044314551.1 1 11 2 0 38 Q8IWT6 5.05e-75 Volume-regulated anion channel subunit LRRC8A (Leucine-rich repeat-containing protein 8A) (HsLRRC8A) (Swelling protein 1) Homo sapiens (Human) anion transmembrane transport [GO:0098656]; anion transport [GO:0006820]; aspartate transmembrane transport [GO:0015810]; cell volume homeostasis [GO:0006884]; cellular glucose homeostasis [GO:0001678]; chloride transmembrane transport [GO:1902476]; cyclic-GMP-AMP transmembrane import across plasma membrane [GO:0140361]; positive regulation of insulin secretion [GO:0032024]; positive regulation of myoblast differentiation [GO:0045663]; pre-B cell differentiation [GO:0002329]; protein hexamerization [GO:0034214]; response to osmotic stress [GO:0006970]; spermatogenesis [GO:0007283]; taurine transport [GO:0015734] GO:0001678; GO:0002329; GO:0005225; GO:0005765; GO:0005886; GO:0006820; GO:0006884; GO:0006970; GO:0007283; GO:0009986; GO:0015734; GO:0015810; GO:0016020; GO:0032024; GO:0034214; GO:0034702; GO:0042802; GO:0045663; GO:0098656; GO:0140360; GO:0140361; GO:1902476 16988 XM_044315498.1 0 0 1 12 6 Q8I7P9 7.39e-39 Retrovirus-related Pol polyprotein from transposon opus [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508]; transposition, DNA-mediated [GO:0006313] GO:0003676; GO:0003887; GO:0003964; GO:0004519; GO:0005634; GO:0006313; GO:0006508; GO:0008233; GO:0015074; GO:0042575 16989 XM_044325617.1 26 34 31 25 61 NA NA NA NA NA NA 16990 XM_044307035.1 16 7 43 26 65 NA NA NA NA NA NA 16991 XM_044312405.1 223 141 352 135 664 NA NA NA NA NA NA 16992 XR_006392832.1 2281 1542 821 1685 263 NA NA NA NA NA NA 16993 XR_006396811.1 110 356 390 311 136 NA NA NA NA NA NA 16994 XM_029328495.2 12 5 14 17 55 NA NA NA NA NA NA 16995 XM_029340273.2 8 7 33 18 0 Q5RA50 3.31e-25 Protein FAM124A Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA NA 16996 XM_029328577.2 7 0 5 14 40 P35348 5.25e-36 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) (Alpha-adrenergic receptor 1c) Homo sapiens (Human) activation of phospholipase C activity [GO:0007202]; adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; adult heart development [GO:0007512]; aging [GO:0007568]; apoptotic process [GO:0006915]; calcium ion transport into cytosol [GO:0060402]; cell growth involved in cardiac muscle cell development [GO:0061049]; cell-cell signaling [GO:0007267]; G protein-coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; micturition [GO:0060073]; multicellular organism aging [GO:0010259]; negative regulation of autophagy [GO:0010507]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure [GO:0001985]; negative regulation of Rho protein signal transduction [GO:0035024]; neuron-glial cell signaling [GO:0150099]; norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001994]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; pilomotor reflex [GO:0097195]; positive regulation of action potential [GO:0045760]; positive regulation of cardiac muscle contraction [GO:0060452]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; positive regulation of systemic arterial blood pressure [GO:0003084]; positive regulation of the force of heart contraction by epinephrine-norepinephrine [GO:0001997]; positive regulation of vasoconstriction [GO:0045907]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; response to hormone [GO:0009725]; response to xenobiotic stimulus [GO:0009410]; signal transduction [GO:0007165]; smooth muscle contraction [GO:0006939] GO:0000165; GO:0001985; GO:0001994; GO:0001996; GO:0001997; GO:0003084; GO:0004930; GO:0004937; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0005901; GO:0006915; GO:0006939; GO:0007165; GO:0007186; GO:0007200; GO:0007202; GO:0007204; GO:0007267; GO:0007512; GO:0007568; GO:0008285; GO:0009410; GO:0009725; GO:0010259; GO:0010507; GO:0010613; GO:0030018; GO:0030315; GO:0031965; GO:0032230; GO:0035024; GO:0035556; GO:0042734; GO:0043231; GO:0043410; GO:0045211; GO:0045760; GO:0045907; GO:0045987; GO:0046982; GO:0060073; GO:0060402; GO:0060452; GO:0061049; GO:0070374; GO:0071880; GO:0090037; GO:0097195; GO:0098691; GO:0098978; GO:0098982; GO:0099171; GO:0150099; GO:1903997 16997 XM_044325497.1 142 30 49 68 92 P07911 1.83e-29 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Homo sapiens (Human) antibacterial innate immune response [GO:0140367]; apoptotic signaling pathway [GO:0097190]; autophagy [GO:0006914]; cellular calcium ion homeostasis [GO:0006874]; cellular chloride ion homeostasis [GO:0030644]; cellular defense response [GO:0006968]; cellular phosphate ion homeostasis [GO:0030643]; cellular response to unfolded protein [GO:0034620]; cellular sodium ion homeostasis [GO:0006883]; chaperone-mediated protein folding [GO:0061077]; citric acid secretion [GO:0046720]; collecting duct development [GO:0072044]; connective tissue replacement [GO:0097709]; creatinine homeostasis [GO:0097273]; defense response to Gram-negative bacterium [GO:0050829]; endoplasmic reticulum organization [GO:0007029]; glomerular filtration [GO:0003094]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; juxtaglomerular apparatus development [GO:0072051]; leukocyte cell-cell adhesion [GO:0007159]; lipid metabolic process [GO:0006629]; metanephric ascending thin limb development [GO:0072218]; metanephric distal convoluted tubule development [GO:0072221]; metanephric thick ascending limb development [GO:0072233]; micturition [GO:0060073]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell population proliferation [GO:0008285]; neutrophil migration [GO:1990266]; organ or tissue specific immune response [GO:0002251]; peptidyl-threonine phosphorylation [GO:0018107]; potassium ion homeostasis [GO:0055075]; protein localization to vacuole [GO:0072665]; protein transport into plasma membrane raft [GO:0044861]; regulation of blood pressure [GO:0008217]; regulation of protein transport [GO:0051223]; regulation of urine volume [GO:0035809]; renal sodium ion absorption [GO:0070294]; renal urate salt excretion [GO:0097744]; renal water homeostasis [GO:0003091]; response to lipopolysaccharide [GO:0032496]; response to water deprivation [GO:0009414]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; ubiquitin-dependent ERAD pathway [GO:0030433]; urate transport [GO:0015747]; urea transmembrane transport [GO:0071918] GO:0000922; GO:0002251; GO:0003091; GO:0003094; GO:0005201; GO:0005509; GO:0005615; GO:0005783; GO:0005796; GO:0005929; GO:0006629; GO:0006874; GO:0006883; GO:0006914; GO:0006954; GO:0006968; GO:0007029; GO:0007157; GO:0007159; GO:0008217; GO:0008285; GO:0008380; GO:0009410; GO:0009414; GO:0009986; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0018107; GO:0019864; GO:0019898; GO:0030433; GO:0030643; GO:0030644; GO:0032496; GO:0033209; GO:0033555; GO:0034620; GO:0035809; GO:0044861; GO:0046720; GO:0050829; GO:0051223; GO:0055075; GO:0060073; GO:0060170; GO:0061077; GO:0070062; GO:0070294; GO:0071918; GO:0072044; GO:0072051; GO:0072218; GO:0072221; GO:0072233; GO:0072665; GO:0097190; GO:0097273; GO:0097709; GO:0097744; GO:0140367; GO:1990266 16998 XM_044319327.1 6 0 1 0 0 NA NA NA NA NA NA 16999 XM_029343340.2 34 46 6 42 33 NA NA NA NA NA NA 17000 XR_006393721.1 0 35 4 57 99 NA NA NA NA NA NA 17001 XM_044310115.1 38 404 5 11 168 NA NA NA NA NA NA 17002 XM_044318609.1 13786 12278 4970 21341 9725 NA NA NA NA NA NA 17003 XM_044312914.1 3 1 3 32 15 P59046 3.22e-36 NACHT, LRR and PYD domains-containing protein 12 (Monarch-1) (PYRIN-containing APAF1-like protein 7) (Regulated by nitric oxide) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cellular response to cytokine stimulus [GO:0071345]; dendritic cell migration [GO:0036336]; ERK1 and ERK2 cascade [GO:0070371]; negative regulation of cytokine production [GO:0001818]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of signal transduction [GO:0009968]; negative regulation of Toll signaling pathway [GO:0045751]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of inflammatory response [GO:0050727]; regulation of interleukin-18 production [GO:0032661]; signal transduction [GO:0007165] GO:0001818; GO:0005524; GO:0005737; GO:0005829; GO:0006919; GO:0007165; GO:0008656; GO:0009968; GO:0031953; GO:0032088; GO:0032661; GO:0032692; GO:0032715; GO:0032731; GO:0036336; GO:0038061; GO:0043122; GO:0043124; GO:0043281; GO:0045345; GO:0045751; GO:0050727; GO:0050728; GO:0050729; GO:0070371; GO:0070373; GO:0071345; GO:1901223; GO:1901224 17004 XM_029335277.2 137 161 100 201 261 Q7ZXT3 4.34e-100 Enhancer of mRNA-decapping protein 4 Xenopus laevis (African clawed frog) deadenylation-independent decapping of nuclear-transcribed mRNA [GO:0031087] GO:0000932; GO:0005634; GO:0031087 17005 XM_029335277.2 137 161 100 201 261 Q7ZXT3 7.83e-63 Enhancer of mRNA-decapping protein 4 Xenopus laevis (African clawed frog) deadenylation-independent decapping of nuclear-transcribed mRNA [GO:0031087] GO:0000932; GO:0005634; GO:0031087 17006 XM_044314229.1 271 141 101 188 129 Q7TSV4 6.86e-113 Phosphopentomutase (EC 5.4.2.7) (Glucose phosphomutase 2) (Phosphodeoxyribomutase) (Phosphoglucomutase-1) (Phosphoglucomutase-2) (PGM 2) (EC 5.4.2.2) Mus musculus (Mouse) glucose metabolic process [GO:0006006]; glycogen catabolic process [GO:0005980]; purine ribonucleoside salvage [GO:0006166] GO:0000287; GO:0004614; GO:0005829; GO:0005980; GO:0006006; GO:0006166; GO:0008973 17007 XM_044318166.1 972 556 513 702 837 Q8BHY8 9.25e-164 Sorting nexin-14 Mus musculus (Mouse) autophagosome maturation [GO:0097352]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; protein transport [GO:0015031] GO:0005764; GO:0005765; GO:0005770; GO:0005829; GO:0015031; GO:0030425; GO:0031902; GO:0035091; GO:0043231; GO:0045202; GO:0080025; GO:0097352; GO:0098794; GO:0099170 17008 XM_044317746.1 12 85 87 0 119 Q8MJU1 3.03e-33 Caspase-3 (CASP-3) (EC 3.4.22.56) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12] Felis catus (Cat) (Felis silvestris catus) apoptotic process [GO:0006915]; erythrocyte differentiation [GO:0030218]; keratinocyte differentiation [GO:0030216]; neuron differentiation [GO:0030182]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; proteolysis [GO:0006508]; regulation of protein stability [GO:0031647] GO:0004175; GO:0005737; GO:0006508; GO:0006915; GO:0030182; GO:0030216; GO:0030218; GO:0031647; GO:0043065; GO:0097153; GO:0097199; GO:0097200; GO:1902004 17009 XM_029348863.2 0 0 124 126 218 P31646 0 Sodium- and chloride-dependent GABA transporter 2 (GAT-2) (Solute carrier family 6 member 13) Rattus norvegicus (Rat) amino acid import across plasma membrane [GO:0089718]; creatine transmembrane transport [GO:0015881]; gamma-aminobutyric acid import [GO:0051939]; monocarboxylic acid transport [GO:0015718]; neurotransmitter transport [GO:0006836]; nitrogen compound transport [GO:0071705]; positive regulation of necrotic cell death [GO:0010940]; sodium ion transmembrane transport [GO:0035725]; taurine transport [GO:0015734] GO:0005283; GO:0005308; GO:0005332; GO:0005368; GO:0005369; GO:0005886; GO:0006836; GO:0008028; GO:0010940; GO:0015171; GO:0015185; GO:0015718; GO:0015734; GO:0015881; GO:0016323; GO:0035725; GO:0042165; GO:0043005; GO:0051939; GO:0071705; GO:0089718 17010 XR_006396720.1 171 87 80 147 121 NA NA NA NA NA NA 17011 XR_003826689.2 910 267 353 292 202 NA NA NA NA NA NA 17012 XM_029349847.2 396 219 225 359 358 NA NA NA NA NA NA 17013 XM_044325254.1 1 4 47 0 69 P19493 3.54e-84 Glutamate receptor 4 (GluR-4) (GluR4) (AMPA-selective glutamate receptor 4) (GluR-D) (Glutamate receptor ionotropic, AMPA 4) (GluA4) Rattus norvegicus (Rat) chemical synaptic transmission [GO:0007268]; chemical synaptic transmission, postsynaptic [GO:0099565]; ion transmembrane transport [GO:0034220]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; regulation of postsynaptic membrane potential [GO:0060078]; regulation of synapse structure or activity [GO:0050803]; response to fungicide [GO:0060992] GO:0004970; GO:0004971; GO:0005886; GO:0007268; GO:0008328; GO:0014069; GO:0015276; GO:0030425; GO:0032281; GO:0032983; GO:0034220; GO:0034392; GO:0038023; GO:0042802; GO:0043025; GO:0043195; GO:0043197; GO:0045202; GO:0048787; GO:0050803; GO:0050804; GO:0051968; GO:0060078; GO:0060992; GO:0098839; GO:0098978; GO:0099507; GO:0099565; GO:1904315 17014 XM_029354846.2 268 51 92 104 266 NA NA NA NA NA NA 17015 XM_044324789.1 359 890 403 629 417 G3V9H8 9.59e-82 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Rattus norvegicus (Rat) cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0007156; GO:0007158; GO:0007169; GO:0007399; GO:0009410; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030182; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0098797 17016 XM_029347407.2 5 22 0 0 10 P70031 4.32e-34 Cholecystokinin receptor (CCK-XLR) Xenopus laevis (African clawed frog) NA GO:0004930; GO:0005886 17017 XR_006393240.1 30 22 0 47 125 NA NA NA NA NA NA 17018 XM_029344310.2 0 0 0 0 52 Q7Z020 8.03e-129 Transient receptor potential cation channel subfamily A member 1 (dTRPA1) (Ankyrin-like with transmembrane domains protein 1) (dANKTM1) Drosophila melanogaster (Fruit fly) calcium ion transport [GO:0006816]; cation transport [GO:0006812]; cellular response to heat [GO:0034605]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; detection of temperature stimulus involved in thermoception [GO:0050960]; mechanosensory behavior [GO:0007638]; negative phototaxis [GO:0046957]; neuronal signal transduction [GO:0023041]; phototransduction [GO:0007602]; positive regulation of calcium-mediated signaling [GO:0050850]; response to heat [GO:0009408]; response to light stimulus [GO:0009416]; temperature compensation of the circadian clock [GO:0010378]; thermosensory behavior [GO:0040040]; thermotaxis [GO:0043052] GO:0001580; GO:0005261; GO:0005262; GO:0005886; GO:0006812; GO:0006816; GO:0007602; GO:0007638; GO:0009408; GO:0009416; GO:0010378; GO:0015276; GO:0016020; GO:0023041; GO:0034605; GO:0034703; GO:0040040; GO:0043052; GO:0046957; GO:0050850; GO:0050960; GO:0050965; GO:0050968; GO:0097604 17019 XM_044324298.1 0 0 0 54 42 NA NA NA NA NA NA 17020 XM_029348190.2 405 216 254 492 492 Q6ZU80 2.86e-31 Centrosomal protein of 128 kDa (Cep128) Homo sapiens (Human) protein localization [GO:0008104] GO:0000922; GO:0005737; GO:0005813; GO:0005814; GO:0008104; GO:0120103 17021 XM_029347548.2 0 0 197 503 965 Q86IC9 5.94e-49 Probable caffeoyl-CoA O-methyltransferase 1 (EC 2.1.1.104) (O-methyltransferase 5) Dictyostelium discoideum (Social amoeba) methylation [GO:0032259] GO:0008757; GO:0032259; GO:0042409; GO:0046872 17022 XM_029323799.2 1057 0 585 652 182 Q7T2C4 3.26e-129 NA NA NA NA 17023 XM_029351083.2 0 0 0 68 17 NA NA NA NA NA NA 17024 XM_044314652.1 30 26 53 102 89 NA NA NA NA NA NA 17025 XM_029334124.2 415 280 214 401 616 NA NA NA NA NA NA 17026 XM_044314577.1 0 26 0 35 45 Q5M7N9 4.76e-76 Extended synaptotagmin-3 (E-Syt3) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) endoplasmic reticulum-plasma membrane tethering [GO:0061817]; lipid transport [GO:0006869] GO:0005789; GO:0005886; GO:0006869; GO:0008289; GO:0046872; GO:0061817; GO:0140268 17027 XM_029327670.2 44 139 165 156 131 Q495W5 1.19e-109 Alpha-(1,3)-fucosyltransferase 11 (EC 2.4.1.-) (Fucosyltransferase XI) (Fuc-TXI) (FucT-XI) (Galactoside 3-L-fucosyltransferase 11) (Fucosyltransferase 11) Homo sapiens (Human) fucosylation [GO:0036065]; N-glycan fucosylation [GO:0036071]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0008417; GO:0032580; GO:0036065; GO:0036071; GO:0046920 17028 XM_029357918.2 73 62 51 60 85 NA NA NA NA NA NA 17029 XM_044312562.1 6 0 0 20 14 NA NA NA NA NA NA 17030 XM_044321618.1 207 98 225 0 404 Q3URQ0 4.07e-58 Testis-expressed protein 10 Mus musculus (Mouse) NA GO:0005634; GO:0005654; GO:0005730; GO:0005739; GO:0071339 17031 XM_029351450.2 913 1061 338 1392 1170 Q9UIK4 1.87e-104 Death-associated protein kinase 2 (DAP kinase 2) (EC 2.7.11.1) (DAP-kinase-related protein 1) (DRP-1) Homo sapiens (Human) anoikis [GO:0043276]; apoptotic process [GO:0006915]; intracellular signal transduction [GO:0035556]; positive regulation of apoptotic process [GO:0043065]; positive regulation of eosinophil chemotaxis [GO:2000424]; positive regulation of neutrophil chemotaxis [GO:0090023]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of autophagy [GO:0010506]; regulation of intrinsic apoptotic signaling pathway [GO:2001242] GO:0004674; GO:0005516; GO:0005524; GO:0005634; GO:0005737; GO:0005794; GO:0006468; GO:0006915; GO:0010506; GO:0031410; GO:0034423; GO:0035556; GO:0042802; GO:0042981; GO:0043065; GO:0043231; GO:0043276; GO:0046777; GO:0090023; GO:0106310; GO:2000424; GO:2001242 17032 XR_006394885.1 537 75 308 325 231 NA NA NA NA NA NA 17033 XM_029324558.2 2544 3472 1209 2285 2505 NA NA NA NA NA NA 17034 XM_044321350.1 27 10 13 7 68 NA NA NA NA NA NA 17035 XM_044311274.1 114 10 0 0 36 F1R4Y7 3.93e-66 Centrosomal protein of 83 kDa (Cep83) (Coiled-coil domain-containing protein 41) Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; establishment of centrosome localization [GO:0051660] GO:0005737; GO:0005814; GO:0051660; GO:0060271; GO:0097539 17036 XM_044326236.1 25 68 18 88 62 NA NA NA NA NA NA 17037 XM_029334971.2 1870 2506 778 1104 1009 A7RM20 0 Eukaryotic translation initiation factor 3 subunit I (eIF3i) Nematostella vectensis (Starlet sea anemone) cytoplasmic translational initiation [GO:0002183]; formation of cytoplasmic translation initiation complex [GO:0001732] GO:0001732; GO:0002183; GO:0003723; GO:0003743; GO:0016282; GO:0033290; GO:0071541 17038 XM_044324409.1 586 520 220 283 571 Q8C206 4.01e-34 G-protein coupled receptor 157 Mus musculus (Mouse) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; circadian behavior [GO:0048512]; G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; radial glial cell differentiation [GO:0060019] GO:0004930; GO:0005886; GO:0007166; GO:0007186; GO:0007189; GO:0048512; GO:0051482; GO:0060019; GO:0060170 17039 XM_044314075.1 176 59 50 61 75 NA NA NA NA NA NA 17040 XM_029355016.2 10 15 2 12 4 NA NA NA NA NA NA 17041 XM_029323483.2 126 132 132 143 183 P34695 1.86e-34 Transcription factor IIIA (TFIIIA) Lithobates pipiens (Northern leopard frog) (Rana pipiens) ribosomal large subunit biogenesis [GO:0042273] GO:0003677; GO:0003723; GO:0005634; GO:0042273; GO:0046872 17042 XR_003827037.2 814 1503 1295 1428 1974 NA NA NA NA NA NA 17043 XM_029328029.2 2421 2000 1898 2529 2815 Q5RA77 0 Coatomer subunit delta (Archain) (Delta-coat protein) (Delta-COP) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) establishment of localization in cell [GO:0051649]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] GO:0000139; GO:0006890; GO:0015031; GO:0030126; GO:0051649 17044 XM_044327160.1 588 665 334 371 678 P13676 0 Acylamino-acid-releasing enzyme (AARE) (EC 3.4.19.1) (Acyl-peptide hydrolase) (APH) (Acylaminoacyl-peptidase) Rattus norvegicus (Rat) amyloid-beta metabolic process [GO:0050435]; proteolysis [GO:0006508] GO:0004252; GO:0005737; GO:0006508; GO:0008242; GO:0042802; GO:0050435 17045 XR_006391805.1 10 0 0 2 0 NA NA NA NA NA NA 17046 XM_029336591.2 303 232 144 114 418 Q5XIN3 2.04e-51 TRAF3-interacting protein 1 (Intraflagellar transport protein 54 homolog) (Microtubule-interacting protein associated with TRAF3) (MIP-T3) Rattus norvegicus (Rat) cilium assembly [GO:0060271]; defense response to virus [GO:0051607]; embryonic camera-type eye development [GO:0031076]; embryonic digit morphogenesis [GO:0042733]; embryonic heart tube development [GO:0035050]; intraciliary transport [GO:0042073]; kidney development [GO:0001822]; morphogenesis of a polarized epithelium [GO:0001738]; negative regulation of defense response to virus [GO:0050687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:1901621]; negative regulation of type I interferon production [GO:0032480]; neural tube patterning [GO:0021532]; post-anal tail morphogenesis [GO:0036342]; regulation of microtubule cytoskeleton organization [GO:0070507]; smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] GO:0001738; GO:0001822; GO:0001933; GO:0005813; GO:0005929; GO:0005930; GO:0008017; GO:0021532; GO:0030992; GO:0031076; GO:0031333; GO:0032480; GO:0032688; GO:0035050; GO:0035869; GO:0036064; GO:0036342; GO:0042073; GO:0042733; GO:0050687; GO:0051607; GO:0060271; GO:0060831; GO:0070507; GO:0097542; GO:0097546; GO:1901621 17047 XM_029336591.2 303 232 144 114 418 Q5XIN3 6.81e-47 TRAF3-interacting protein 1 (Intraflagellar transport protein 54 homolog) (Microtubule-interacting protein associated with TRAF3) (MIP-T3) Rattus norvegicus (Rat) cilium assembly [GO:0060271]; defense response to virus [GO:0051607]; embryonic camera-type eye development [GO:0031076]; embryonic digit morphogenesis [GO:0042733]; embryonic heart tube development [GO:0035050]; intraciliary transport [GO:0042073]; kidney development [GO:0001822]; morphogenesis of a polarized epithelium [GO:0001738]; negative regulation of defense response to virus [GO:0050687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:1901621]; negative regulation of type I interferon production [GO:0032480]; neural tube patterning [GO:0021532]; post-anal tail morphogenesis [GO:0036342]; regulation of microtubule cytoskeleton organization [GO:0070507]; smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] GO:0001738; GO:0001822; GO:0001933; GO:0005813; GO:0005929; GO:0005930; GO:0008017; GO:0021532; GO:0030992; GO:0031076; GO:0031333; GO:0032480; GO:0032688; GO:0035050; GO:0035869; GO:0036064; GO:0036342; GO:0042073; GO:0042733; GO:0050687; GO:0051607; GO:0060271; GO:0060831; GO:0070507; GO:0097542; GO:0097546; GO:1901621 17048 XM_029328002.2 9 2 16 0 8 Q5SUE8 1.39e-25 Ankyrin repeat domain-containing protein 40 Mus musculus (Mouse) NA NA 17049 XM_029339543.2 202 89 94 65 207 Q8BFQ2 1.72e-42 Transmembrane protein 229B Mus musculus (Mouse) macrophage activation [GO:0042116]; response to bacterium [GO:0009617] GO:0009617; GO:0016020; GO:0042116 17050 XM_029345466.2 219 6 248 31 533 Q8N2E2 2e-39 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 17051 XM_029345466.2 219 6 248 31 533 Q8N2E2 1.2e-37 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 17052 XM_029345466.2 219 6 248 31 533 Q8N2E2 2.11e-36 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 17053 XM_029345466.2 219 6 248 31 533 Q8N2E2 6.56e-35 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 17054 XM_029345466.2 219 6 248 31 533 Q8N2E2 7.6e-32 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 17055 XM_029345466.2 219 6 248 31 533 Q8N2E2 5.4e-25 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 17056 XM_044319098.1 19 2 45 15 181 Q94887 3.53e-35 Neurexin-4 (Neurexin IV) Drosophila melanogaster (Fruit fly) axon ensheathment [GO:0008366]; cell adhesion involved in heart morphogenesis [GO:0061343]; cell-cell junction organization [GO:0045216]; dorsal closure [GO:0007391]; establishment of glial blood-brain barrier [GO:0060857]; heart process [GO:0003015]; nerve maturation [GO:0021682]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]; synaptic target recognition [GO:0008039]; terminal button organization [GO:0072553] GO:0003015; GO:0005886; GO:0005919; GO:0007391; GO:0008039; GO:0008104; GO:0008366; GO:0019991; GO:0021682; GO:0035151; GO:0045202; GO:0045216; GO:0048786; GO:0060857; GO:0061343; GO:0072553; GO:0097105 17057 XM_044323007.1 122 156 146 0 212 Q9LHQ6 8.81e-56 Organic cation/carnitine transporter 4 (AtOCT4) Arabidopsis thaliana (Mouse-ear cress) cellular response to water deprivation [GO:0042631]; ion transport [GO:0006811] GO:0005524; GO:0006811; GO:0009535; GO:0009705; GO:0022857; GO:0042631 17058 XR_006392150.1 12 11 7 14 23 NA NA NA NA NA NA 17059 XM_029341148.2 84 215 69 197 194 P41969 4.87e-21 ETS domain-containing protein Elk-1 Mus musculus (Mouse) cell differentiation [GO:0030154]; cellular response to gamma radiation [GO:0071480]; cellular response to lipid [GO:0071396]; cellular response to testosterone stimulus [GO:0071394]; gene expression [GO:0010467]; liver development [GO:0001889]; lung development [GO:0030324]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of neuron death [GO:1901216]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; response to fibroblast growth factor [GO:0071774]; response to light stimulus [GO:0009416] GO:0000976; GO:0000978; GO:0000981; GO:0001228; GO:0001889; GO:0003682; GO:0003690; GO:0003700; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0006355; GO:0006357; GO:0009416; GO:0010467; GO:0030154; GO:0030324; GO:0030374; GO:0030425; GO:0043025; GO:0043679; GO:0045893; GO:0045944; GO:0061629; GO:0071394; GO:0071396; GO:0071480; GO:0071774; GO:1901216; GO:1990837 17060 XM_029335571.2 0 13 58 28 0 P55006 4.99e-77 Retinol dehydrogenase 7 (EC 1.1.1.105) (Retinol dehydrogenase 3) (Retinol dehydrogenase type III) (RODH III) Rattus norvegicus (Rat) retinol metabolic process [GO:0042572]; steroid metabolic process [GO:0008202] GO:0004745; GO:0005783; GO:0008202; GO:0016491; GO:0042572; GO:0043231 17061 XM_029358599.2 1476 1067 723 1463 1001 O95995 0 Dynein regulatory complex subunit 4 (Growth arrest-specific protein 11) (GAS-11) (Growth arrest-specific protein 8) (GAS-8) Homo sapiens (Human) axoneme assembly [GO:0035082]; brain development [GO:0007420]; cilium movement involved in cell motility [GO:0060294]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of protein localization to cilium [GO:1903566]; positive regulation of smoothened signaling pathway [GO:0045880]; protein localization [GO:0008104]; regulation of microtubule binding [GO:1904526] GO:0003351; GO:0005576; GO:0005794; GO:0005829; GO:0005874; GO:0005886; GO:0005929; GO:0005930; GO:0007368; GO:0007420; GO:0008017; GO:0008104; GO:0008285; GO:0030317; GO:0031267; GO:0031514; GO:0035082; GO:0036064; GO:0036126; GO:0045880; GO:0051649; GO:0060294; GO:1903566; GO:1904526 17062 XM_044328793.1 5 12 13 24 31 E9Q236 0 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 17063 XM_044328793.1 5 12 13 24 31 E9Q236 2.32e-154 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 17064 XM_029346844.2 641 431 249 385 258 Q8R5L3 0 Vam6/Vps39-like protein Mus musculus (Mouse) autophagosome-lysosome fusion [GO:0061909]; autophagy [GO:0006914]; endocytic recycling [GO:0032456]; endosomal vesicle fusion [GO:0034058]; endosome to lysosome transport [GO:0008333]; intracellular protein transport [GO:0006886]; late endosome to lysosome transport [GO:1902774] GO:0005737; GO:0005765; GO:0005770; GO:0006886; GO:0006914; GO:0008333; GO:0016020; GO:0030897; GO:0031902; GO:0032456; GO:0034058; GO:0061909; GO:1902501; GO:1902774 17065 XM_029334388.2 1456 1677 888 1226 1214 NA NA NA NA NA NA 17066 XM_044320897.1 6815 3976 2383 4403 2544 P11884 0 Aldehyde dehydrogenase, mitochondrial (EC 1.2.1.3) (ALDH class 2) (ALDH-E2) (ALDH1) Rattus norvegicus (Rat) acetaldehyde metabolic process [GO:0006117]; aldehyde catabolic process [GO:0046185]; apoptotic mitochondrial changes [GO:0008637]; behavioral response to ethanol [GO:0048149]; cellular detoxification of aldehyde [GO:0110095]; cellular response to fatty acid [GO:0071398]; cellular response to hormone stimulus [GO:0032870]; cellular response to resveratrol [GO:1904639]; ethanol catabolic process [GO:0006068]; ethanol metabolic process [GO:0006067]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; liver development [GO:0001889]; negative regulation of apoptotic process [GO:0043066]; regulation of dopamine biosynthetic process [GO:1903179]; regulation of inflammatory response [GO:0050727]; regulation of reactive oxygen species metabolic process [GO:2000377]; regulation of response to oxidative stress [GO:1902882]; regulation of serotonin biosynthetic process [GO:1905627]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to organic cyclic compound [GO:0014070]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574] GO:0001889; GO:0002931; GO:0004029; GO:0005739; GO:0005759; GO:0006067; GO:0006068; GO:0006117; GO:0008631; GO:0008637; GO:0008957; GO:0009408; GO:0014070; GO:0018547; GO:0032355; GO:0032496; GO:0032570; GO:0032870; GO:0033574; GO:0035094; GO:0042802; GO:0043066; GO:0043878; GO:0045471; GO:0046185; GO:0048149; GO:0050727; GO:0052689; GO:0055093; GO:0070404; GO:0071398; GO:0110095; GO:1902882; GO:1903179; GO:1904639; GO:1905627; GO:2000377 17067 XM_029334475.2 366 5 642 61 1 Q8R4G6 1.19e-178 Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (EC 2.4.1.155) (Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase) (GlcNAc-T V) (GNT-V) (Mannoside acetylglucosaminyltransferase 5) (N-acetylglucosaminyl-transferase V) [Cleaved into: Secreted alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (Secreted beta-1,6-N-acetylglucosaminyltransferase V) (Secreted GNT-V)] Mus musculus (Mouse) negative regulation of protein tyrosine phosphatase activity [GO:1903614]; positive regulation of cell migration [GO:0030335]; positive regulation of receptor signaling pathway via STAT [GO:1904894]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279] GO:0000139; GO:0004864; GO:0005576; GO:0005794; GO:0006487; GO:0008375; GO:0016020; GO:0016757; GO:0018279; GO:0030144; GO:0030145; GO:0030335; GO:0043204; GO:1903614; GO:1904894 17068 XM_029334475.2 366 5 642 61 1 Q8R4G6 2.48e-29 Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (EC 2.4.1.155) (Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase) (GlcNAc-T V) (GNT-V) (Mannoside acetylglucosaminyltransferase 5) (N-acetylglucosaminyl-transferase V) [Cleaved into: Secreted alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (Secreted beta-1,6-N-acetylglucosaminyltransferase V) (Secreted GNT-V)] Mus musculus (Mouse) negative regulation of protein tyrosine phosphatase activity [GO:1903614]; positive regulation of cell migration [GO:0030335]; positive regulation of receptor signaling pathway via STAT [GO:1904894]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279] GO:0000139; GO:0004864; GO:0005576; GO:0005794; GO:0006487; GO:0008375; GO:0016020; GO:0016757; GO:0018279; GO:0030144; GO:0030145; GO:0030335; GO:0043204; GO:1903614; GO:1904894 17069 XM_044312568.1 203 27 14 192 28 Q5XFW6 2.34e-112 WD repeat-containing protein 6 Rattus norvegicus (Rat) G1 to G0 transition [GO:0070314]; insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009]; negative regulation of autophagy [GO:0010507]; negative regulation of cell population proliferation [GO:0008285]; tRNA methylation [GO:0030488] GO:0005737; GO:0008285; GO:0008286; GO:0010507; GO:0030488; GO:0032991; GO:0043560; GO:0048009; GO:0070314 17070 XM_029335297.2 5 224 528 504 0 NA NA NA NA NA NA 17071 XM_029347723.2 306 489 103 879 76 Q96CG8 6.35e-36 Collagen triple helix repeat-containing protein 1 Homo sapiens (Human) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005576; GO:0005581; GO:0005615; GO:0016477; GO:0016528; GO:0017147; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0062023; GO:0090090; GO:0090103; GO:0090177 17072 XM_044327222.1 7743 8221 3678 6374 4657 P31674 4.83e-46 40S ribosomal protein S15 Oryza sativa subsp. japonica (Rice) ribosomal small subunit assembly [GO:0000028]; translation [GO:0006412] GO:0000028; GO:0003723; GO:0003735; GO:0006412; GO:0022627 17073 XM_044316983.1 166 143 110 66 83 NA NA NA NA NA NA 17074 XM_044312754.1 0 0 4 26 31 NA NA NA NA NA NA 17075 XM_029342040.2 23 44 482 98 0 Q90683 1.17e-35 Transcription factor 4 (TCF-4) (Class A helix-loop-helix transcription factor GE2) Gallus gallus (Chicken) positive regulation of neuron differentiation [GO:0045666]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005667; GO:0006357; GO:0045666; GO:0046982; GO:0070888 17076 XM_044314447.1 102 68 0 0 100 Q5RED7 7.66e-70 Acylglycerol kinase, mitochondrial (EC 2.7.1.107) (EC 2.7.1.138) (EC 2.7.1.94) (Multiple substrate lipid kinase) (MuLK) (Multi-substrate lipid kinase) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) ceramide biosynthetic process [GO:0046513]; glycerolipid metabolic process [GO:0046486]; protein insertion into mitochondrial inner membrane [GO:0045039] GO:0001729; GO:0004143; GO:0005524; GO:0005743; GO:0005758; GO:0031966; GO:0042721; GO:0045039; GO:0046486; GO:0046513; GO:0047620; GO:0102773 17077 XR_006393731.1 0 0 0 16 0 NA NA NA NA NA NA 17078 XR_006392505.1 66 44 14 10 21 NA NA NA NA NA NA 17079 XR_003825453.2 112 60 64 4 269 NA NA NA NA NA NA 17080 XM_029326411.2 1 42 44 17 6 NA NA NA NA NA NA 17081 XM_044328189.1 337 56 195 370 129 P48547 1.2e-115 Potassium voltage-gated channel subfamily C member 1 (NGK2) (Voltage-gated potassium channel subunit Kv3.1) (Voltage-gated potassium channel subunit Kv4) Homo sapiens (Human) cellular response to xenobiotic stimulus [GO:0071466]; cerebellum development [GO:0021549]; corpus callosum development [GO:0022038]; globus pallidus development [GO:0021759]; optic nerve development [GO:0021554]; positive regulation of voltage-gated potassium channel activity [GO:1903818]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; protein tetramerization [GO:0051262]; response to amine [GO:0014075]; response to auditory stimulus [GO:0010996]; response to fibroblast growth factor [GO:0071774]; response to light intensity [GO:0009642]; response to nerve growth factor [GO:1990089]; response to potassium ion [GO:0035864]; response to toxic substance [GO:0009636] GO:0005249; GO:0005251; GO:0005886; GO:0006813; GO:0008076; GO:0009636; GO:0009642; GO:0009986; GO:0010996; GO:0014075; GO:0016020; GO:0019894; GO:0021549; GO:0021554; GO:0021759; GO:0022038; GO:0030424; GO:0030673; GO:0032590; GO:0032809; GO:0035864; GO:0042734; GO:0044305; GO:0044325; GO:0045211; GO:0051260; GO:0051262; GO:0071466; GO:0071774; GO:0071805; GO:0099508; GO:1903818; GO:1990089 17082 XM_044328568.1 0 0 14 0 0 NA NA NA NA NA NA 17083 XM_044312437.1 177 142 14 6 15 NA NA NA NA NA NA 17084 XM_044309377.1 0 8 0 2 1 NA NA NA NA NA NA 17085 XM_029337074.2 121 317 60 194 513 NA NA NA NA NA NA 17086 XM_029335329.2 237 53 161 112 248 NA NA NA NA NA NA 17087 XM_029330531.2 274 454 313 675 212 NA NA NA NA NA NA 17088 XM_044306833.1 36 0 0 36 0 NA NA NA NA NA NA 17089 XR_006397031.1 118 12 21 412 55 NA NA NA NA NA NA 17090 XR_003825566.2 350 30 454 460 156 NA NA NA NA NA NA 17091 XM_029330741.2 1 0 12 0 41 Q98T88 1.36e-28 Twisted gastrulation protein homolog 1-A Xenopus laevis (African clawed frog) NA GO:0005576 17092 XM_029343662.2 93 58 164 85 55 Q05360 2.76e-168 Protein white Lucilia cuprina (Green bottle fly) (Australian sheep blowfly) NA GO:0005524; GO:0016020; GO:0016887; GO:0031409; GO:0140359 17093 XR_006391442.1 11 0 0 0 4 NA NA NA NA NA NA 17094 XM_029335266.2 716 430 260 538 555 Q90WU3 0 ATP-dependent RNA helicase DDX1 (EC 3.6.4.13) (DEAD box protein 1) Gallus gallus (Chicken) DNA duplex unwinding [GO:0032508]; double-strand break repair [GO:0006302]; mRNA processing [GO:0006397]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388] GO:0003677; GO:0003682; GO:0003712; GO:0003724; GO:0004518; GO:0004527; GO:0005524; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0006302; GO:0006388; GO:0006397; GO:0008143; GO:0016887; GO:0032508; GO:0033677; GO:0072669 17095 XM_029332573.2 174 244 146 242 161 NA NA NA NA NA NA 17096 XM_029333833.2 286 139 199 238 308 NA NA NA NA NA NA 17097 XM_029328390.2 15758 13575 7669 11220 12694 NA NA NA NA NA NA 17098 XM_029349397.2 135 117 60 104 159 Q498J9 3.4e-54 Metallo-beta-lactamase domain-containing protein 1 (EC 3.1.27.-) (Endoribonuclease MBLAC1) Xenopus laevis (African clawed frog) histone mRNA metabolic process [GO:0008334]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087] GO:0004521; GO:0005634; GO:0005737; GO:0005829; GO:0008334; GO:0046872; GO:1900087 17099 XM_029331597.2 1652 688 789 1541 1219 NA NA NA NA NA NA 17100 XM_044328085.1 63 99 34 113 30 NA NA NA NA NA NA 17101 XM_044308643.1 1871 1421 1149 2326 3293 Q2KHZ9 0 Glutaryl-CoA dehydrogenase, mitochondrial (GCD) (EC 1.3.8.6) Bos taurus (Bovine) fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; fatty-acyl-CoA biosynthetic process [GO:0046949]; tryptophan metabolic process [GO:0006568] GO:0000062; GO:0004361; GO:0005759; GO:0006568; GO:0033539; GO:0046949; GO:0050660 17102 XM_044310900.1 0 0 14 6 9 NA NA NA NA NA NA 17103 XR_006395310.1 3168 3637 4204 5122 3803 NA NA NA NA NA NA 17104 XM_044313559.1 0 0 54 0 0 Q6DJM7 1.16e-140 Cyclin-dependent kinase 14 (EC 2.7.11.22) (Cell division protein kinase 14) Xenopus laevis (African clawed frog) cell division [GO:0051301]; G2/M transition of mitotic cell cycle [GO:0000086]; protein phosphorylation [GO:0006468]; regulation of canonical Wnt signaling pathway [GO:0060828]; Wnt signaling pathway [GO:0016055] GO:0000086; GO:0000308; GO:0004693; GO:0005524; GO:0005886; GO:0006468; GO:0016055; GO:0051301; GO:0060828; GO:0106310 17105 XM_029351914.2 198 143 101 132 144 NA NA NA NA NA NA 17106 XR_006397750.1 5 26 23 2 66 NA NA NA NA NA NA 17107 XR_003823844.2 1 26 33 18 12 NA NA NA NA NA NA 17108 XM_029340288.2 306 165 86 200 346 Q9UKJ3 7.31e-42 G patch domain-containing protein 8 Homo sapiens (Human) NA GO:0003723; GO:0005634; GO:0046872 17109 XM_044324503.1 1536 765 795 1045 924 Q92551 1.48e-98 Inositol hexakisphosphate kinase 1 (InsP6 kinase 1) (EC 2.7.4.21) (Inositol hexaphosphate kinase 1) Homo sapiens (Human) inositol phosphate biosynthetic process [GO:0032958]; inositol phosphate metabolic process [GO:0043647]; negative regulation of cold-induced thermogenesis [GO:0120163]; phosphatidylinositol phosphate biosynthetic process [GO:0046854]; phosphorylation [GO:0016310] GO:0000827; GO:0000828; GO:0000829; GO:0000832; GO:0001650; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0016301; GO:0016310; GO:0032958; GO:0043647; GO:0046854; GO:0052723; GO:0052724; GO:0052836; GO:0052839; GO:0120163 17110 XM_044309424.1 191 297 418 423 357 Q6AXK4 2.42e-39 BRISC and BRCA1-A complex member 1 (Mediator of RAP80 interactions and targeting subunit of 40 kDa) (New component of the BRCA1-A complex) Danio rerio (Zebrafish) (Brachydanio rerio) cell division [GO:0051301]; chromatin organization [GO:0006325]; double-strand break repair [GO:0006302]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; positive regulation of DNA repair [GO:0045739]; protein K63-linked deubiquitination [GO:0070536]; response to ionizing radiation [GO:0010212] GO:0005634; GO:0005737; GO:0006302; GO:0006325; GO:0007095; GO:0010212; GO:0016604; GO:0045739; GO:0051301; GO:0070531; GO:0070536; GO:0070552 17111 XM_044309811.1 1030 309 407 1087 1000 Q3UHC7 2.68e-144 Disabled homolog 2-interacting protein (DAB2-interacting protein) (ASK-interacting protein 1) (DOC-2/DAB-2 interactive protein) Mus musculus (Mouse) angiogenesis [GO:0001525]; cell cycle [GO:0007049]; cell motility involved in cerebral cortex radial glia guided migration [GO:0021814]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; I-kappaB phosphorylation [GO:0007252]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; layer formation in cerebral cortex [GO:0021819]; negative regulation of angiogenesis [GO:0016525]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of G0 to G1 transition [GO:0070317]; negative regulation of GTPase activity [GO:0034260]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of phosphatidylinositol 3-kinase activity [GO:0043553]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of Ras protein signal transduction [GO:0046580]; negative regulation of toll-like receptor 4 signaling pathway [GO:0034144]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; negative regulation of vascular endothelial growth factor signaling pathway [GO:1900747]; neuron projection morphogenesis [GO:0048812]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of dendrite development [GO:1900006]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron migration [GO:2001224]; positive regulation of neuron projection development [GO:0010976]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of protein-containing complex assembly [GO:0031334]; positive regulation of synapse maturation [GO:0090129]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein catabolic process [GO:0030163]; regulation of cell cycle [GO:0051726]; regulation of GTPase activity [GO:0043087]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of p38MAPK cascade [GO:1900744]; regulation of protein-containing complex assembly [GO:0043254]; response to unfolded protein [GO:0006986]; tube formation [GO:0035148]; vascular endothelial growth factor receptor-2 signaling pathway [GO:0036324] GO:0000122; GO:0001525; GO:0001933; GO:0005096; GO:0005123; GO:0005737; GO:0005886; GO:0006954; GO:0006986; GO:0007049; GO:0007252; GO:0008285; GO:0008625; GO:0010596; GO:0010633; GO:0010719; GO:0010976; GO:0014067; GO:0016525; GO:0017124; GO:0019900; GO:0019901; GO:0021814; GO:0021819; GO:0030139; GO:0030163; GO:0030308; GO:0030424; GO:0030425; GO:0030948; GO:0031334; GO:0031434; GO:0031435; GO:0032088; GO:0032266; GO:0032809; GO:0034144; GO:0034260; GO:0035148; GO:0035591; GO:0035924; GO:0036312; GO:0036324; GO:0042059; GO:0042177; GO:0042802; GO:0042803; GO:0043025; GO:0043065; GO:0043087; GO:0043122; GO:0043124; GO:0043184; GO:0043254; GO:0043407; GO:0043410; GO:0043507; GO:0043539; GO:0043548; GO:0043553; GO:0044300; GO:0044301; GO:0044877; GO:0045087; GO:0045732; GO:0045892; GO:0045944; GO:0046330; GO:0046580; GO:0047485; GO:0048147; GO:0048812; GO:0050679; GO:0050680; GO:0051721; GO:0051726; GO:0070059; GO:0070273; GO:0070317; GO:0070373; GO:0071222; GO:0071347; GO:0071356; GO:0071364; GO:0071889; GO:0071901; GO:0071902; GO:0090090; GO:0090129; GO:1900006; GO:1900744; GO:1900747; GO:1901800; GO:1990032; GO:1990597; GO:2001224; GO:2001235 17112 XM_029331856.2 909 912 626 1036 1021 Q60HE6 0 Double-strand break repair protein MRE11 (EC 3.1.-.-) (Double-strand break repair protein MRE11A) (Meiotic recombination 11 homolog A) (MRE11 homolog A) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) cellular response to DNA damage stimulus [GO:0006974]; DNA strand resection involved in replication fork processing [GO:0110025]; double-strand break repair via homologous recombination [GO:0000724]; meiotic cell cycle [GO:0051321] GO:0000724; GO:0000781; GO:0004520; GO:0005657; GO:0006974; GO:0008296; GO:0008409; GO:0030145; GO:0030870; GO:0035861; GO:0051321; GO:0110025 17113 XM_044322620.1 143 50 50 85 73 Q6AZW2 2.01e-90 Aldo-keto reductase family 1 member A1-A (Alcohol dehydrogenase [NADP(+)] A) (EC 1.1.1.2) (Aldehyde reductase-A) Danio rerio (Zebrafish) (Brachydanio rerio) aldehyde catabolic process [GO:0046185]; cellular detoxification of aldehyde [GO:0110095] GO:0004032; GO:0005829; GO:0016324; GO:0046185; GO:0110095 17114 XM_044329137.1 280 257 53 67 304 P21265 0 Adenylosuccinate lyase (ADSL) (ASL) (EC 4.3.2.2) (Adenylosuccinase) (ASase) Gallus gallus (Chicken) 'de novo' AMP biosynthetic process [GO:0044208]; 'de novo' IMP biosynthetic process [GO:0006189]; 'de novo' XMP biosynthetic process [GO:0097294]; AMP salvage [GO:0044209]; GMP biosynthetic process [GO:0006177] GO:0004018; GO:0005829; GO:0006177; GO:0006189; GO:0032991; GO:0042802; GO:0044208; GO:0044209; GO:0070626; GO:0097294 17115 XM_044323039.1 36 12 44 48 45 Q6P1L5 7.93e-26 Protein FAM117B (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 13 protein) Homo sapiens (Human) NA NA 17116 XM_044325996.1 709 411 331 447 1020 Q924S5 0 Lon protease homolog, mitochondrial (EC 3.4.21.53) (Lon protease-like protein) (LONP) (Mitochondrial ATP-dependent protease Lon) (Serine protease 15) Rattus norvegicus (Rat) aging [GO:0007568]; cellular response to oxidative stress [GO:0034599]; chaperone-mediated protein complex assembly [GO:0051131]; mitochondrion organization [GO:0007005]; negative regulation of insulin receptor signaling pathway [GO:0046627]; oxidation-dependent protein catabolic process [GO:0070407]; protein catabolic process [GO:0030163]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; protein-containing complex assembly [GO:0065003]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; response to aluminum ion [GO:0010044]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666] GO:0001018; GO:0001666; GO:0003697; GO:0003727; GO:0004176; GO:0004252; GO:0005524; GO:0005654; GO:0005739; GO:0005759; GO:0005829; GO:0006508; GO:0006515; GO:0007005; GO:0007568; GO:0009725; GO:0010044; GO:0016887; GO:0030163; GO:0034599; GO:0042645; GO:0042731; GO:0042802; GO:0043531; GO:0043560; GO:0043565; GO:0046627; GO:0050730; GO:0051131; GO:0051603; GO:0051880; GO:0065003; GO:0070182; GO:0070407 17117 XM_029337830.2 143 0 0 766 214 O75762 1.24e-95 Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation-sensitive protein p120) (p120) (Wasabi receptor) Homo sapiens (Human) calcium ion transmembrane transport [GO:0070588]; cell surface receptor signaling pathway [GO:0007166]; cellular calcium ion homeostasis [GO:0006874]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to organic substance [GO:0071310]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; ion transport [GO:0006811]; protein homotetramerization [GO:0051289]; response to cold [GO:0009409]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; sensory perception of pain [GO:0019233]; thermoception [GO:0050955] GO:0005262; GO:0005886; GO:0006811; GO:0006874; GO:0007166; GO:0009409; GO:0009410; GO:0010033; GO:0014070; GO:0015267; GO:0015278; GO:0019233; GO:0032421; GO:0042802; GO:0048265; GO:0050955; GO:0050966; GO:0050968; GO:0051289; GO:0070301; GO:0070588; GO:0071310; GO:0097604 17118 XR_006396074.1 0 0 0 9 0 NA NA NA NA NA NA 17119 XM_029336145.2 278 202 123 676 162 P61460 0 GATOR complex protein DEPDC5 (DEP domain-containing protein 5) Mus musculus (Mouse) cellular response to amino acid starvation [GO:0034198]; intracellular signal transduction [GO:0035556]; negative regulation of TOR signaling [GO:0032007]; negative regulation of TORC1 signaling [GO:1904262]; positive regulation of autophagy [GO:0010508] GO:0005096; GO:0005764; GO:0005765; GO:0005829; GO:0010508; GO:0031463; GO:0032007; GO:0034198; GO:0035556; GO:0044877; GO:0048471; GO:1904262; GO:1990130 17120 XM_029336145.2 278 202 123 676 162 P61460 4.79e-53 GATOR complex protein DEPDC5 (DEP domain-containing protein 5) Mus musculus (Mouse) cellular response to amino acid starvation [GO:0034198]; intracellular signal transduction [GO:0035556]; negative regulation of TOR signaling [GO:0032007]; negative regulation of TORC1 signaling [GO:1904262]; positive regulation of autophagy [GO:0010508] GO:0005096; GO:0005764; GO:0005765; GO:0005829; GO:0010508; GO:0031463; GO:0032007; GO:0034198; GO:0035556; GO:0044877; GO:0048471; GO:1904262; GO:1990130 17121 XR_006395026.1 0 0 8 0 0 NA NA NA NA NA NA 17122 XM_044311484.1 12 1 0 0 8 NA NA NA NA NA NA 17123 XR_003823645.2 0 0 12 0 20 NA NA NA NA NA NA 17124 XM_029349833.2 207 58 164 102 470 Q8NBL1 7.91e-168 Protein O-glucosyltransferase 1 (EC 2.4.1.376) (CAP10-like 46 kDa protein) (hCLP46) (KTEL motif-containing protein 1) (Myelodysplastic syndromes relative protein) (O-glucosyltransferase Rumi homolog) (hRumi) (Protein O-xylosyltransferase POGLUT1) (EC 2.4.2.63) Homo sapiens (Human) axial mesoderm development [GO:0048318]; circulatory system development [GO:0072359]; gastrulation [GO:0007369]; muscle tissue development [GO:0060537]; paraxial mesoderm development [GO:0048339]; positive regulation of Notch signaling pathway [GO:0045747]; protein O-linked glycosylation [GO:0006493]; protein O-linked glycosylation via serine [GO:0018242]; regulation of gastrulation [GO:0010470]; somitogenesis [GO:0001756] GO:0001756; GO:0005783; GO:0005788; GO:0006493; GO:0007369; GO:0010470; GO:0012505; GO:0018242; GO:0035251; GO:0035252; GO:0045747; GO:0046527; GO:0048318; GO:0048339; GO:0060537; GO:0072359; GO:0140561; GO:0140562 17125 XM_029342449.2 226 95 47 131 230 NA NA NA NA NA NA 17126 XM_029334369.2 124 159 558 409 5 NA NA NA NA NA NA 17127 XM_044325634.1 1569 906 735 1647 605 P98133 5.86e-97 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 17128 XM_044325634.1 1569 906 735 1647 605 P98133 4.37e-95 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 17129 XM_044325634.1 1569 906 735 1647 605 P98133 3.65e-93 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 17130 XM_044325634.1 1569 906 735 1647 605 P98133 3.79e-91 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 17131 XM_044325634.1 1569 906 735 1647 605 P98133 1.81e-90 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 17132 XM_044325634.1 1569 906 735 1647 605 P98133 2.75e-84 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 17133 XM_044325634.1 1569 906 735 1647 605 P98133 5.64e-82 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 17134 XM_044325634.1 1569 906 735 1647 605 P98133 2.48e-76 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 17135 XM_044325634.1 1569 906 735 1647 605 P98133 5.89e-70 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 17136 XM_044325634.1 1569 906 735 1647 605 P98133 2.77e-47 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 17137 XM_044325634.1 1569 906 735 1647 605 P98133 1.65e-23 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 17138 XM_044315505.1 2 0 17 0 14 NA NA NA NA NA NA 17139 XM_029347110.2 5 44 119 9 22 NA NA NA NA NA NA 17140 XM_029356662.2 694 623 322 390 533 NA NA NA NA NA NA 17141 XM_029325503.2 563 199 438 485 402 Q9VWN9 1.14e-163 Zinc finger SWIM domain-containing protein 8 homolog (Protein dorado) Drosophila melanogaster (Fruit fly) positive regulation of miRNA catabolic process [GO:2000627]; protein ubiquitination [GO:0016567] GO:0008270; GO:0016567; GO:0031462; GO:1990756; GO:2000627 17142 XM_029325503.2 563 199 438 485 402 Q9VWN9 5.02e-63 Zinc finger SWIM domain-containing protein 8 homolog (Protein dorado) Drosophila melanogaster (Fruit fly) positive regulation of miRNA catabolic process [GO:2000627]; protein ubiquitination [GO:0016567] GO:0008270; GO:0016567; GO:0031462; GO:1990756; GO:2000627 17143 XM_029325503.2 563 199 438 485 402 Q9VWN9 1.52e-52 Zinc finger SWIM domain-containing protein 8 homolog (Protein dorado) Drosophila melanogaster (Fruit fly) positive regulation of miRNA catabolic process [GO:2000627]; protein ubiquitination [GO:0016567] GO:0008270; GO:0016567; GO:0031462; GO:1990756; GO:2000627 17144 XM_029325503.2 563 199 438 485 402 Q9VWN9 1.35e-46 Zinc finger SWIM domain-containing protein 8 homolog (Protein dorado) Drosophila melanogaster (Fruit fly) positive regulation of miRNA catabolic process [GO:2000627]; protein ubiquitination [GO:0016567] GO:0008270; GO:0016567; GO:0031462; GO:1990756; GO:2000627 17145 XM_029335519.2 882 175 335 834 713 Q61035 0 Histidine--tRNA ligase, cytoplasmic (EC 6.1.1.21) (Histidyl-tRNA synthetase) (HisRS) Mus musculus (Mouse) histidyl-tRNA aminoacylation [GO:0006427]; mitochondrial translation [GO:0032543] GO:0004821; GO:0005524; GO:0005737; GO:0005739; GO:0005829; GO:0006427; GO:0032543; GO:0042802; GO:0042803 17146 XM_044306967.1 5 8 2 2 1 NA NA NA NA NA NA 17147 XR_006397499.1 337 274 235 376 292 NA NA NA NA NA NA 17148 XM_044320060.1 828 1081 512 558 179 Q4G0X4 5.57e-22 BTB/POZ domain-containing protein KCTD21 (KCASH2 protein) (Potassium channel tetramerization domain-containing protein 21) Homo sapiens (Human) negative regulation of smoothened signaling pathway [GO:0045879]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0006511; GO:0016567; GO:0042802; GO:0042826; GO:0045879; GO:0051260; GO:0097602 17149 XM_044320060.1 828 1081 512 558 179 Q4G0X4 3.94e-21 BTB/POZ domain-containing protein KCTD21 (KCASH2 protein) (Potassium channel tetramerization domain-containing protein 21) Homo sapiens (Human) negative regulation of smoothened signaling pathway [GO:0045879]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0006511; GO:0016567; GO:0042802; GO:0042826; GO:0045879; GO:0051260; GO:0097602 17150 XM_044328024.1 9 200 0 63 18 NA NA NA NA NA NA 17151 XM_029345950.2 1156 643 102 511 258 Q91175 5.19e-38 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (MAR1) Oryzias latipes (Japanese rice fish) (Japanese killifish) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of vasoconstriction [GO:0045907] GO:0001996; GO:0004930; GO:0004937; GO:0005886; GO:0007200; GO:0007204; GO:0007267; GO:0043410; GO:0045907; GO:0071880 17152 XM_029341297.2 186 317 95 283 228 NA NA NA NA NA NA 17153 XM_044307468.1 22 61 7 19 32 NA NA NA NA NA NA 17154 XR_006395897.1 21 57 59 26 65 NA NA NA NA NA NA 17155 XM_029329147.2 488 483 39 491 1191 Q12802 5.43e-82 A-kinase anchor protein 13 (AKAP-13) (AKAP-Lbc) (Breast cancer nuclear receptor-binding auxiliary protein) (Guanine nucleotide exchange factor Lbc) (Human thyroid-anchoring protein 31) (Lymphoid blast crisis oncogene) (LBC oncogene) (Non-oncogenic Rho GTPase-specific GTP exchange factor) (Protein kinase A-anchoring protein 13) (PRKA13) (p47) Homo sapiens (Human) adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process [GO:0086023]; adrenergic receptor signaling pathway [GO:0071875]; bone development [GO:0060348]; cardiac muscle cell differentiation [GO:0055007]; cell growth involved in cardiac muscle cell development [GO:0061049]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; nuclear export [GO:0051168]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Rho protein signal transduction [GO:0035025]; regulation of Rho protein signal transduction [GO:0035023]; regulation of sarcomere organization [GO:0060297]; regulation of small GTPase mediated signal transduction [GO:0051056] GO:0005078; GO:0005085; GO:0005634; GO:0005829; GO:0005938; GO:0007186; GO:0007507; GO:0016020; GO:0031267; GO:0035023; GO:0035025; GO:0043123; GO:0043406; GO:0046872; GO:0048471; GO:0051018; GO:0051056; GO:0051168; GO:0055007; GO:0060090; GO:0060297; GO:0060348; GO:0061049; GO:0071875; GO:0086023 17156 XM_044320993.1 0 0 43 0 0 NA NA NA NA NA NA 17157 XR_006394260.1 11 4 43 9 189 NA NA NA NA NA NA 17158 XM_044308826.1 34 0 0 1 43 NA NA NA NA NA NA 17159 XM_029334894.2 116 75 120 129 174 NA NA NA NA NA NA 17160 XM_029329360.2 202 273 107 106 148 NA NA NA NA NA NA 17161 XM_044313181.1 32 83 30 41 2 NA NA NA NA NA NA 17162 XM_029338969.2 40 107 22 141 46 P10079 3.17e-51 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 17163 XM_029338969.2 40 107 22 141 46 P10079 6.74e-48 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 17164 XM_029338969.2 40 107 22 141 46 P10079 3e-47 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 17165 XM_029338969.2 40 107 22 141 46 P10079 1.03e-46 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 17166 XM_029338969.2 40 107 22 141 46 P10079 1.07e-42 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 17167 XM_029338969.2 40 107 22 141 46 P10079 7.14e-42 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 17168 XM_029338969.2 40 107 22 141 46 P10079 2.19e-41 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 17169 XM_029338969.2 40 107 22 141 46 P10079 1.25e-40 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 17170 XM_029338969.2 40 107 22 141 46 P10079 8.57e-39 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 17171 XM_029338969.2 40 107 22 141 46 P10079 3.95e-34 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 17172 XM_044321315.1 15 30 68 0 134 Q80TR4 1.05e-22 Slit homolog 1 protein (Slit-1) Mus musculus (Mouse) axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; dorsal/ventral axon guidance [GO:0033563]; motor neuron axon guidance [GO:0008045]; negative chemotaxis [GO:0050919]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of synapse assembly [GO:0051964]; neuron projection morphogenesis [GO:0048812]; nuclear migration [GO:0007097]; olfactory bulb development [GO:0021772]; retinal ganglion cell axon guidance [GO:0031290]; spinal cord development [GO:0021510]; tangential migration from the subventricular zone to the olfactory bulb [GO:0022028]; telencephalon cell migration [GO:0022029] GO:0005102; GO:0005509; GO:0005615; GO:0005886; GO:0007097; GO:0007409; GO:0007411; GO:0008045; GO:0008201; GO:0021510; GO:0021772; GO:0022028; GO:0022029; GO:0031290; GO:0033563; GO:0043395; GO:0048495; GO:0048812; GO:0048843; GO:0048846; GO:0050919; GO:0051964 17173 XM_044321408.1 1015 646 719 887 613 Q2M389 0 WASH complex subunit 4 (Strumpellin and WASH-interacting protein) (SWIP) (WASH complex subunit SWIP) Homo sapiens (Human) endosomal transport [GO:0016197]; endosome organization [GO:0007032]; nuclear envelope budding [GO:0140591]; protein transport [GO:0015031]; regulation of Arp2/3 complex-mediated actin nucleation [GO:0034315] GO:0005654; GO:0005768; GO:0007032; GO:0015031; GO:0016197; GO:0031901; GO:0034315; GO:0071203; GO:0140591 17174 XR_006391669.1 235 118 0 37 96 NA NA NA NA NA NA 17175 XR_006393924.1 12 0 14 0 73 NA NA NA NA NA NA 17176 XM_029344223.2 357 212 205 269 211 Q8WY64 6.17e-43 E3 ubiquitin-protein ligase MYLIP (EC 2.3.2.27) (Inducible degrader of the LDL-receptor) (Idol) (Myosin regulatory light chain interacting protein) (MIR) (RING-type E3 ubiquitin transferase MYLIP) Homo sapiens (Human) cholesterol homeostasis [GO:0042632]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of neuron projection development [GO:0010977]; nervous system development [GO:0007399]; positive regulation of protein catabolic process [GO:0045732]; protein destabilization [GO:0031648]; protein ubiquitination [GO:0016567]; regulation of low-density lipoprotein particle receptor catabolic process [GO:0032803]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004842; GO:0005829; GO:0005856; GO:0005886; GO:0006511; GO:0007399; GO:0008092; GO:0010977; GO:0010989; GO:0016567; GO:0031648; GO:0032803; GO:0042632; GO:0045732; GO:0046872; GO:0061630 17177 XM_044324508.1 11 0 0 167 0 Q7Z4T9 0 Cilia- and flagella-associated protein 91 (CFAP91) (AMY-1-associating protein expressed in testis 1) (AAT-1) (MYCBP/AMY-1-associated testis-expressed protein 1) (Protein MAATS1) Homo sapiens (Human) axonemal central apparatus assembly [GO:1904158]; cell differentiation [GO:0030154]; cilium movement [GO:0003341]; spermatogenesis [GO:0007283] GO:0003341; GO:0005739; GO:0005930; GO:0007283; GO:0030154; GO:0031514; GO:1904158 17178 XM_044313703.1 0 0 0 59 0 Q9W735 1.41e-86 Prominin-1-A (Prominin-like protein 1) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005783; GO:0005793; GO:0005886; GO:0005902; GO:0005929; GO:0009986; GO:0015485; GO:0016324; GO:0031528; GO:0071914 17179 XM_029344288.2 3150 2799 2106 1687 1918 Q96LT7 1.35e-68 Guanine nucleotide exchange factor C9orf72 Homo sapiens (Human) autophagy [GO:0006914]; axon extension [GO:0048675]; endocytosis [GO:0006897]; late endosome to lysosome transport [GO:1902774]; negative regulation of exocytosis [GO:0045920]; negative regulation of GTP binding [GO:1904425]; negative regulation of immune response [GO:0050777]; negative regulation of protein phosphorylation [GO:0001933]; positive regulation of GTPase activity [GO:0043547]; positive regulation of macroautophagy [GO:0016239]; regulation of actin filament organization [GO:0110053]; regulation of autophagosome assembly [GO:2000785]; regulation of autophagy [GO:0010506]; regulation of protein localization [GO:0032880]; regulation of TORC1 signaling [GO:1903432]; stress granule assembly [GO:0034063] GO:0000932; GO:0001933; GO:0005085; GO:0005615; GO:0005634; GO:0005737; GO:0005764; GO:0005768; GO:0005776; GO:0005829; GO:0006897; GO:0006914; GO:0010494; GO:0010506; GO:0016239; GO:0030425; GO:0031267; GO:0031965; GO:0032045; GO:0032880; GO:0034063; GO:0043204; GO:0043231; GO:0043547; GO:0044295; GO:0044304; GO:0045920; GO:0048675; GO:0050777; GO:0090543; GO:0098793; GO:0098794; GO:0110053; GO:1902774; GO:1903432; GO:1904425; GO:2000785 17180 XM_029336089.2 201 214 296 346 167 NA NA NA NA NA NA 17181 XR_006393223.1 634 383 474 794 1461 NA NA NA NA NA NA 17182 XM_029356287.2 19555 22044 15524 18202 23490 Q3T0B7 1.09e-34 40S ribosomal protein S27-like Bos taurus (Bovine) ribosomal small subunit assembly [GO:0000028]; translation [GO:0006412] GO:0000028; GO:0003723; GO:0003735; GO:0006412; GO:0022627; GO:0046872 17183 XM_029350197.2 21 18 18 19 0 NA NA NA NA NA NA 17184 XM_044320078.1 37 19 9 38 14 Q8N2E2 1.11e-56 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 17185 XM_029329995.2 177 110 468 157 234 NA NA NA NA NA NA 17186 XM_044313831.1 0 3 2 6 9 NA NA NA NA NA NA 17187 XM_029355908.2 543 328 399 531 318 O00534 5.23e-130 von Willebrand factor A domain-containing protein 5A (Breast cancer suppressor candidate 1) (BCSC-1) (Loss of heterozygosity 11 chromosomal region 2 gene A protein) Homo sapiens (Human) NA GO:0005654 17188 XM_044325380.1 0 12 54 0 44 O88943 6.85e-73 Potassium voltage-gated channel subfamily KQT member 2 (KQT-like 2) (Potassium channel subunit alpha KvLQT2) (Voltage-gated potassium channel subunit Kv7.2) Rattus norvegicus (Rat) ion transmembrane transport [GO:0034220]; membrane hyperpolarization [GO:0060081]; potassium ion transmembrane transport [GO:0071805]; regulation of ion transmembrane transport [GO:0034765]; transmission of nerve impulse [GO:0019226] GO:0005244; GO:0005249; GO:0005251; GO:0005516; GO:0005886; GO:0008076; GO:0009986; GO:0016020; GO:0019226; GO:0030506; GO:0032991; GO:0033268; GO:0034220; GO:0034765; GO:0043194; GO:0047485; GO:0060081; GO:0071805 17189 XM_029352853.2 4 0 6 9 14 NA NA NA NA NA NA 17190 XM_029345213.2 2197 1920 1384 2669 2922 Q8QZV1 2.43e-128 High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (EC 3.1.4.35) Rattus norvegicus (Rat) cGMP catabolic process [GO:0046069]; cGMP metabolic process [GO:0046068]; cGMP-mediated signaling [GO:0019934]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165] GO:0004114; GO:0005654; GO:0005783; GO:0005794; GO:0005829; GO:0007165; GO:0010613; GO:0019934; GO:0032587; GO:0042383; GO:0043204; GO:0046068; GO:0046069; GO:0046872; GO:0047555; GO:0048471 17191 XM_044325418.1 73 122 22 22 27 NA NA NA NA NA NA 17192 XM_044329138.1 257 124 228 330 477 P21265 0 Adenylosuccinate lyase (ADSL) (ASL) (EC 4.3.2.2) (Adenylosuccinase) (ASase) Gallus gallus (Chicken) 'de novo' AMP biosynthetic process [GO:0044208]; 'de novo' IMP biosynthetic process [GO:0006189]; 'de novo' XMP biosynthetic process [GO:0097294]; AMP salvage [GO:0044209]; GMP biosynthetic process [GO:0006177] GO:0004018; GO:0005829; GO:0006177; GO:0006189; GO:0032991; GO:0042802; GO:0044208; GO:0044209; GO:0070626; GO:0097294 17193 XM_044314038.1 47 20 39 44 75 NA NA NA NA NA NA 17194 XM_029332844.2 81 71 30 87 93 NA NA NA NA NA NA 17195 XM_029329678.2 71 16 50 85 34 NA NA NA NA NA NA 17196 XM_044317431.1 87 2 45 40 118 Q90805 1.46e-52 Cyclic nucleotide-gated channel cone photoreceptor subunit alpha (CNG channel 1) (CNG-1) (CNG1) Gallus gallus (Chicken) cation transmembrane transport [GO:0098655]; response to stimulus [GO:0050896]; visual perception [GO:0007601] GO:0005222; GO:0005223; GO:0005886; GO:0007601; GO:0017071; GO:0030552; GO:0030553; GO:0044877; GO:0050896; GO:0098655 17197 XM_044317431.1 87 2 45 40 118 Q90805 3.28e-37 Cyclic nucleotide-gated channel cone photoreceptor subunit alpha (CNG channel 1) (CNG-1) (CNG1) Gallus gallus (Chicken) cation transmembrane transport [GO:0098655]; response to stimulus [GO:0050896]; visual perception [GO:0007601] GO:0005222; GO:0005223; GO:0005886; GO:0007601; GO:0017071; GO:0030552; GO:0030553; GO:0044877; GO:0050896; GO:0098655 17198 XM_044316626.1 626 57 78 416 670 Q8RWL6 5.9e-29 Serine/threonine-protein kinase STY17 (EC 2.7.11.1) (Serine/threonine/tyrosine-protein kinase 17) Arabidopsis thaliana (Mouse-ear cress) chloroplast organization [GO:0009658]; protein phosphorylation [GO:0006468] GO:0004674; GO:0004712; GO:0005524; GO:0005829; GO:0006468; GO:0009658; GO:0106310 17199 XM_044316626.1 626 57 78 416 670 Q8RWL6 8.61e-29 Serine/threonine-protein kinase STY17 (EC 2.7.11.1) (Serine/threonine/tyrosine-protein kinase 17) Arabidopsis thaliana (Mouse-ear cress) chloroplast organization [GO:0009658]; protein phosphorylation [GO:0006468] GO:0004674; GO:0004712; GO:0005524; GO:0005829; GO:0006468; GO:0009658; GO:0106310 17200 XM_044323441.1 437 293 162 307 263 P41976 4.55e-92 Superoxide dismutase [Mn], mitochondrial (EC 1.15.1.1) Bos taurus (Bovine) cellular response to oxidative stress [GO:0034599]; regulation of transcription by RNA polymerase II [GO:0006357]; superoxide metabolic process [GO:0006801] GO:0004784; GO:0005739; GO:0005759; GO:0006357; GO:0006801; GO:0030145; GO:0034599 17201 XM_044328118.1 3 0 5 0 13 NA NA NA NA NA NA 17202 XM_044316048.1 5 0 7 0 8 NA NA NA NA NA NA 17203 XM_044322387.1 0 79 0 8 0 P0DH96 6.53e-25 Calmodulin-4 (CaM-4) Arabidopsis thaliana (Mouse-ear cress) NA GO:0005509 17204 XM_044325855.1 0 61 0 0 0 NA NA NA NA NA NA 17205 XM_044316652.1 59697 19882 5278 25612 37418 NA NA NA NA NA NA 17206 XM_029332646.2 1308 1566 1442 2417 2048 NA NA NA NA NA NA 17207 XR_003826271.2 3 4 3 14 9 NA NA NA NA NA NA 17208 XM_044310549.1 198 73 29 88 43 NA NA NA NA NA NA 17209 XM_044309036.1 196 13 121 16 0 Q4R642 1.45e-149 Dynein regulatory complex subunit 5 (T-complex-associated testis-expressed protein 1) (Tcte-1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) flagellated sperm motility [GO:0030317] GO:0005737; GO:0005856; GO:0030317; GO:0036126 17210 XM_029338420.2 83 0 276 84 48 Q0E908 5.58e-39 Hillarin (D-Hillarin) (D-hil) Drosophila melanogaster (Fruit fly) NA GO:0005938; GO:0032154; GO:0046872 17211 XM_044312628.1 253 178 235 116 486 Q9D071 1.31e-158 MMS19 nucleotide excision repair protein homolog (MET18 homolog) (MMS19-like protein) Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; chromosome segregation [GO:0007059]; DNA metabolic process [GO:0006259]; DNA repair [GO:0006281]; iron-sulfur cluster assembly [GO:0016226]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; protein maturation by iron-sulfur cluster transfer [GO:0097428] GO:0003713; GO:0005634; GO:0005654; GO:0005737; GO:0005819; GO:0005829; GO:0006259; GO:0006281; GO:0006974; GO:0007059; GO:0016226; GO:0019899; GO:0030331; GO:0045893; GO:0071817; GO:0097361; GO:0097428; GO:1905168 17212 XM_044309991.1 8 0 44 56 0 NA NA NA NA NA NA 17213 XM_044318233.1 47 26 19 48 59 E7FAM5 4.83e-90 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 17214 XR_006394096.1 76 41 117 129 213 NA NA NA NA NA NA 17215 XM_029338122.2 27 55 45 13 70 NA NA NA NA NA NA 17216 XM_029344966.2 1765 1823 785 1227 1075 Q62862 0 Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase 5) (MAPKK 5) (EC 2.7.12.2) (MAPK/ERK kinase 5) (MEK 5) Rattus norvegicus (Rat) cellular response to growth factor stimulus [GO:0071363]; ERK5 cascade [GO:0070375]; heart development [GO:0007507]; insulin-like growth factor receptor signaling pathway [GO:0048009]; MAPK cascade [GO:0000165]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000342]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of response to cytokine stimulus [GO:0060761]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cell growth [GO:0030307]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein phosphorylation [GO:0006468] GO:0000122; GO:0000165; GO:0004672; GO:0004707; GO:0004708; GO:0004713; GO:0005524; GO:0005634; GO:0005819; GO:0005829; GO:0006468; GO:0007507; GO:0016020; GO:0030307; GO:0032088; GO:0032717; GO:0034115; GO:0043154; GO:0043406; GO:0043539; GO:0045944; GO:0046872; GO:0048009; GO:0050679; GO:0051247; GO:0060761; GO:0070375; GO:0071363; GO:0090051; GO:0106310; GO:2000342; GO:2001240 17217 XM_044320143.1 1 0 0 0 6 NA NA NA NA NA NA 17218 XR_006393284.1 0 6 0 0 0 NA NA NA NA NA NA 17219 XM_044327229.1 2217 2226 1266 2359 2868 Q9JJP9 7.4e-72 Ubiquilin-1 (Protein linking IAP with cytoskeleton 1) (PLIC-1) Rattus norvegicus (Rat) aggrephagy [GO:0035973]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; cellular response to hypoxia [GO:0071456]; macroautophagy [GO:0016236]; negative regulation of store-operated calcium channel activity [GO:1901340]; negative regulation of toll-like receptor 3 signaling pathway [GO:0034140]; positive regulation of ER-associated ubiquitin-dependent protein catabolic process [GO:1903071]; positive regulation of protein ubiquitination [GO:0031398]; regulation of macroautophagy [GO:0016241]; regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902175]; regulation of protein ubiquitination [GO:0031396]; response to endoplasmic reticulum stress [GO:0034976]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000045; GO:0000502; GO:0005634; GO:0005737; GO:0005776; GO:0005783; GO:0005829; GO:0005886; GO:0006511; GO:0016235; GO:0016236; GO:0016241; GO:0019900; GO:0019904; GO:0030433; GO:0031396; GO:0031398; GO:0031410; GO:0031593; GO:0034140; GO:0034976; GO:0035973; GO:0042802; GO:0048471; GO:0071456; GO:0097352; GO:1901340; GO:1902175; GO:1903071 17220 XM_029325499.2 3 6 5 2 16 NA NA NA NA NA NA 17221 XM_029327368.2 1517 1784 1269 1721 1645 P83686 1.37e-118 NADH-cytochrome b5 reductase 3 (B5R) (Cytochrome b5 reductase) (EC 1.6.2.2) (Diaphorase-1) Sus scrofa (Pig) cholesterol biosynthetic process [GO:0006695] GO:0004128; GO:0005741; GO:0005789; GO:0006695; GO:0050660; GO:0071949 17222 XM_044308288.1 19 4 19 36 28 NA NA NA NA NA NA 17223 XM_029348018.2 308 190 76 247 219 NA NA NA NA NA NA 17224 XM_029337187.2 33 62 91 172 234 NA NA NA NA NA NA 17225 XM_044319602.1 12 5 4 43 32 NA NA NA NA NA NA 17226 XM_029329751.2 404 137 6 61 170 NA NA NA NA NA NA 17227 XM_029338812.2 2448 926 701 2145 1328 B3EX01 2.75e-82 CUB domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 17228 XM_029338812.2 2448 926 701 2145 1328 B3EX01 4.36e-76 CUB domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 17229 XM_044313104.1 0 18 0 0 16 NA NA NA NA NA NA 17230 XM_044320421.1 0 0 0 120 0 NA NA NA NA NA NA 17231 XM_044320586.1 502 112 0 0 0 NA NA NA NA NA NA 17232 XM_029345884.2 28 143 101 161 7 NA NA NA NA NA NA 17233 XM_029336664.2 11 13 3 7 3 NA NA NA NA NA NA 17234 XM_044314044.1 15 23 1 2 5 NA NA NA NA NA NA 17235 XM_044312709.1 65 52 31 75 30 NA NA NA NA NA NA 17236 XM_044327091.1 338 187 196 214 159 P48416 2.58e-77 Cytochrome P450 10 (EC 1.14.-.-) (CYPX) Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004497; GO:0005506; GO:0016705; GO:0020037 17237 XM_044306927.1 753 298 421 586 374 Q8IVE3 0 Pleckstrin homology domain-containing family H member 2 Homo sapiens (Human) negative regulation of actin filament depolymerization [GO:0030835] GO:0003779; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0016604; GO:0030027; GO:0030835; GO:0030864 17238 XM_029343187.2 17 98 40 114 75 NA NA NA NA NA NA 17239 XM_044322174.1 52 197 146 461 487 NA NA NA NA NA NA 17240 XR_006395192.1 9 0 18 3 1 NA NA NA NA NA NA 17241 XM_029340103.2 133 118 34 68 23 Q05688 1.04e-73 Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Bos taurus (Bovine) cellular response to glucose stimulus [GO:0071333]; glucose homeostasis [GO:0042593]; insulin-like growth factor receptor signaling pathway [GO:0048009]; negative regulation of apoptotic process [GO:0043066]; negative regulation of MAPK cascade [GO:0043409]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; protein autophosphorylation [GO:0046777]; regulation of JNK cascade [GO:0046328]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0004713; GO:0004714; GO:0005009; GO:0005010; GO:0005198; GO:0005520; GO:0005524; GO:0005737; GO:0005886; GO:0005899; GO:0007169; GO:0014068; GO:0030424; GO:0033674; GO:0042593; GO:0043066; GO:0043235; GO:0043409; GO:0043410; GO:0043548; GO:0043560; GO:0046328; GO:0046777; GO:0048009; GO:0051897; GO:0071333 17242 XR_003825218.2 6 0 5 4 0 NA NA NA NA NA NA 17243 XM_044315322.1 30 20 26 186 112 NA NA NA NA NA NA 17244 XM_044327002.1 312 163 182 282 326 NA NA NA NA NA NA 17245 XM_044326558.1 0 27 0 0 0 NA NA NA NA NA NA 17246 XM_044312288.1 0 0 52 0 0 Q9U6Y6 2.64e-109 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 17247 XM_044324459.1 29 0 31 0 29 NA NA NA NA NA NA 17248 XM_029346886.2 2582 2393 1860 2701 2729 Q9UMY4 2.84e-69 Sorting nexin-12 Homo sapiens (Human) endocytic recycling [GO:0032456]; late endosome to Golgi transport [GO:0034499]; negative regulation of early endosome to late endosome transport [GO:2000642]; negative regulation of gene expression [GO:0010629]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein processing [GO:0010955]; negative regulation of protein transport [GO:0051224]; protein transport [GO:0015031]; regulation of endocytosis [GO:0030100] GO:0005769; GO:0010629; GO:0010955; GO:0015031; GO:0019899; GO:0030100; GO:0030904; GO:0031901; GO:0032266; GO:0032456; GO:0034499; GO:0035091; GO:0042177; GO:0051224; GO:2000642 17249 XR_006397989.1 609 602 361 584 596 NA NA NA NA NA NA 17250 XM_029337302.2 510 520 457 850 670 NA NA NA NA NA NA 17251 XM_029352769.2 20 0 5 7 0 NA NA NA NA NA NA 17252 XM_029342869.2 10 0 3 0 29 NA NA NA NA NA NA 17253 XR_006394302.1 11 125 55 57 6 NA NA NA NA NA NA 17254 XM_029342770.2 0 0 0 0 35 Q9GZV8 1.82e-137 PR domain zinc finger protein 14 (EC 2.1.1.-) (PR domain-containing protein 14) Homo sapiens (Human) cell fate specification [GO:0001708]; cell morphogenesis [GO:0000902]; embryo implantation [GO:0007566]; fertilization [GO:0009566]; fibroblast growth factor receptor signaling pathway [GO:0008543]; germ cell development [GO:0007281]; germ-line stem cell population maintenance [GO:0030718]; histone H3-R26 methylation [GO:0034972]; homeostasis of number of cells within a tissue [GO:0048873]; inactivation of paternal X chromosome [GO:0060817]; inner cell mass cell fate commitment [GO:0001827]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of flagellated sperm motility [GO:1902093]; positive regulation of stem cell population maintenance [GO:1902459]; regulation of DNA methylation [GO:0044030]; regulation of gene expression [GO:0010468]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000902; GO:0000977; GO:0001708; GO:0001827; GO:0003723; GO:0005634; GO:0005654; GO:0006357; GO:0007281; GO:0007566; GO:0008168; GO:0008543; GO:0009566; GO:0010468; GO:0030718; GO:0031490; GO:0034972; GO:0040037; GO:0044030; GO:0046872; GO:0048873; GO:0060817; GO:1902093; GO:1902459 17255 XM_029335888.2 1065 1124 844 908 881 Q8BHA3 3.04e-59 D-aminoacyl-tRNA deacylase 2 (EC 3.1.1.96) (Animalia-specific tRNA deacylase) (ATD) (D-tyrosyl-tRNA deacylase 2) (L-alanyl-tRNA deacylase) Mus musculus (Mouse) aminoacyl-tRNA metabolism involved in translational fidelity [GO:0106074]; tRNA metabolic process [GO:0006399] GO:0000049; GO:0005737; GO:0006399; GO:0051500; GO:0106074; GO:0106105 17256 XM_029346535.2 117 0 0 53 314 P32297 7.23e-93 Neuronal acetylcholine receptor subunit alpha-3 Homo sapiens (Human) acetylcholine receptor signaling pathway [GO:0095500]; activation of transmembrane receptor protein tyrosine kinase activity [GO:0007171]; behavioral response to nicotine [GO:0035095]; chemical synaptic transmission [GO:0007268]; excitatory postsynaptic potential [GO:0060079]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; locomotory behavior [GO:0007626]; membrane depolarization [GO:0051899]; nervous system development [GO:0007399]; nervous system process [GO:0050877]; regulation of acetylcholine secretion, neurotransmission [GO:0014056]; regulation of dendrite morphogenesis [GO:0048814]; regulation of membrane potential [GO:0042391]; regulation of smooth muscle contraction [GO:0006940]; response to acetylcholine [GO:1905144]; signal transduction [GO:0007165]; synaptic transmission involved in micturition [GO:0060084]; synaptic transmission, cholinergic [GO:0007271] GO:0005231; GO:0005886; GO:0005892; GO:0006811; GO:0006940; GO:0007165; GO:0007171; GO:0007268; GO:0007271; GO:0007399; GO:0007626; GO:0014056; GO:0014069; GO:0015276; GO:0015464; GO:0016020; GO:0016607; GO:0022848; GO:0030425; GO:0030594; GO:0034220; GO:0035095; GO:0042166; GO:0042391; GO:0043005; GO:0043025; GO:0044853; GO:0045202; GO:0045211; GO:0048814; GO:0050877; GO:0051899; GO:0060079; GO:0060084; GO:0095500; GO:1904315; GO:1905144 17257 XM_044319673.1 78 107 23 46 59 A0A2B4RNI3 2.19e-25 NA NA NA NA 17258 XM_044312286.1 2 0 1 8 8 Q5R5U3 1.98e-103 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 17259 XM_044312286.1 2 0 1 8 8 Q5R5U3 2.71e-102 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 17260 XM_044312286.1 2 0 1 8 8 Q5R5U3 4.79e-101 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 17261 XM_044312286.1 2 0 1 8 8 Q5R5U3 4.54e-100 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 17262 XM_044312286.1 2 0 1 8 8 Q5R5U3 3.58e-99 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 17263 XM_044312286.1 2 0 1 8 8 Q5R5U3 6.5e-98 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 17264 XM_044312286.1 2 0 1 8 8 Q5R5U3 1.2e-97 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 17265 XM_044312286.1 2 0 1 8 8 Q5R5U3 4.32e-97 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 17266 XM_044312286.1 2 0 1 8 8 Q5R5U3 6.98e-97 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 17267 XM_044312286.1 2 0 1 8 8 Q5R5U3 6.72e-94 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 17268 XM_044312286.1 2 0 1 8 8 Q5R5U3 2.38e-88 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 17269 XM_044312286.1 2 0 1 8 8 Q5R5U3 3.54e-74 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 17270 XM_044312286.1 2 0 1 8 8 Q5R5U3 2.66e-42 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 17271 XM_044310864.1 68 0 2 73 2 NA NA NA NA NA NA 17272 XR_006394687.1 0 16 0 133 288 NA NA NA NA NA NA 17273 XR_006393478.1 13 0 0 0 0 NA NA NA NA NA NA 17274 XR_006392895.1 41 2 25 5 151 NA NA NA NA NA NA 17275 XM_029352684.2 1516 1152 1003 1116 1146 NA NA NA NA NA NA 17276 XR_003822982.2 0 0 7 7 6 NA NA NA NA NA NA 17277 XM_029344076.2 14 0 0 0 7 NA NA NA NA NA NA 17278 XM_029356620.2 54 104 74 40 25 NA NA NA NA NA NA 17279 XM_029356813.2 3448 3030 2003 2881 3247 P60517 4.6e-75 Gamma-aminobutyric acid receptor-associated protein (GABA(A) receptor-associated protein) Rattus norvegicus (Rat) autophagosome assembly [GO:0000045]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; macroautophagy [GO:0016236]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein K48-linked ubiquitination [GO:1902524]; protein transport [GO:0015031]; regulation of Rac protein signal transduction [GO:0035020] GO:0000045; GO:0000139; GO:0000226; GO:0000421; GO:0000422; GO:0005764; GO:0005776; GO:0005790; GO:0005794; GO:0005829; GO:0005874; GO:0005875; GO:0005886; GO:0005930; GO:0006995; GO:0008017; GO:0008625; GO:0015031; GO:0015629; GO:0016236; GO:0031410; GO:0031625; GO:0032436; GO:0035020; GO:0044297; GO:0048471; GO:0048487; GO:0050811; GO:0097225; GO:1902524 17280 XM_029341323.2 165 179 103 108 260 Q7TMF2 3.6e-87 3'-5' exoribonuclease 1 (EC 3.1.-.-) (3'-5' exonuclease ERI1) (Eri-1 homolog) (Histone mRNA 3'-exonuclease 1) Mus musculus (Mouse) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; RNA-mediated gene silencing [GO:0031047]; rRNA 3'-end processing [GO:0031125] GO:0000175; GO:0000467; GO:0005634; GO:0005730; GO:0005737; GO:0008408; GO:0019843; GO:0031047; GO:0031125; GO:0043022; GO:0046872; GO:0071204; GO:0071207 17281 XM_044320348.1 8 52 0 103 110 NA NA NA NA NA NA 17282 XM_029348376.2 509 314 214 356 498 Q9CXX9 4.75e-39 CUE domain-containing protein 2 Mus musculus (Mouse) negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of macrophage cytokine production [GO:0010936] GO:0005654; GO:0005829; GO:0010936; GO:0031965; GO:0043130; GO:1900016 17283 XM_029330337.2 1222 674 981 1598 688 Q6W2J9 6.47e-42 BCL-6 corepressor (BCoR) Homo sapiens (Human) blastocyst hatching [GO:0001835]; chromatin remodeling [GO:0006338]; heart development [GO:0007507]; negative regulation of bone mineralization [GO:0030502]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of histone H3-K36 methylation [GO:0000415]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of tooth mineralization [GO:0070171]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; protein ubiquitination [GO:0016567]; roof of mouth development [GO:0060021]; specification of axis polarity [GO:0065001] GO:0000122; GO:0000415; GO:0000976; GO:0000977; GO:0001835; GO:0003714; GO:0005634; GO:0005654; GO:0006338; GO:0007507; GO:0016567; GO:0030502; GO:0031072; GO:0042476; GO:0042826; GO:0045892; GO:0051572; GO:0060021; GO:0065001; GO:0070171; GO:0140261; GO:0140297 17284 XM_044317029.1 0 6 0 7 15 NA NA NA NA NA NA 17285 XM_044328099.1 228 200 48 182 228 Q8NI77 7.94e-168 Kinesin-like protein KIF18A (Marrow stromal KIF18A) (MS-KIF18A) Homo sapiens (Human) cellular response to estradiol stimulus [GO:0071392]; male meiotic nuclear division [GO:0007140]; microtubule depolymerization [GO:0007019]; microtubule-based movement [GO:0007018]; mitotic metaphase plate congression [GO:0007080]; mitotic sister chromatid segregation [GO:0000070]; protein transport [GO:0015031]; regulation of microtubule cytoskeleton organization [GO:0070507]; seminiferous tubule development [GO:0072520] GO:0000070; GO:0000776; GO:0001726; GO:0003777; GO:0003779; GO:0005524; GO:0005634; GO:0005737; GO:0005815; GO:0005828; GO:0005829; GO:0005871; GO:0005874; GO:0005901; GO:0007018; GO:0007019; GO:0007080; GO:0007140; GO:0008017; GO:0008574; GO:0015031; GO:0015630; GO:0016887; GO:0051010; GO:0061673; GO:0070463; GO:0070507; GO:0071392; GO:0072520; GO:1990023 17286 XM_029333438.2 325 0 0 0 243 P55115 9.81e-48 Zinc metalloproteinase nas-15 (EC 3.4.24.-) (Nematode astacin 15) Caenorhabditis elegans proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0006508; GO:0008270 17287 XM_044326004.1 0 45 67 6 3 NA NA NA NA NA NA 17288 XM_029348250.2 3753 4053 2460 2486 2492 NA NA NA NA NA NA 17289 XM_044323611.1 0 36 13 0 0 NA NA NA NA NA NA 17290 XM_044318007.1 7036 8738 5433 6087 3409 Q5XIP1 0 Protein pelota homolog (EC 3.1.-.-) Rattus norvegicus (Rat) cell cycle [GO:0007049]; cell division [GO:0051301]; chromosome organization [GO:0051276]; endoderm development [GO:0007492]; inner cell mass cell proliferation [GO:0001833]; mesenchymal to epithelial transition [GO:0060231]; nonfunctional rRNA decay [GO:0070651]; nuclear-transcribed mRNA catabolic process, no-go decay [GO:0070966]; nuclear-transcribed mRNA catabolic process, non-stop decay [GO:0070481]; positive regulation of BMP signaling pathway [GO:0030513]; regulation of translation [GO:0006417]; ribosome disassembly [GO:0032790]; RNA surveillance [GO:0071025]; stem cell population maintenance [GO:0019827] GO:0001833; GO:0004519; GO:0005634; GO:0005737; GO:0006417; GO:0007049; GO:0007492; GO:0019827; GO:0030513; GO:0032790; GO:0046872; GO:0051276; GO:0051301; GO:0060231; GO:0070481; GO:0070651; GO:0070966; GO:0071025 17291 XM_029342602.2 0 0 0 175 0 Q9VBW3 3.64e-85 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 17292 XM_044324634.1 101 52 93 54 139 NA NA NA NA NA NA 17293 XM_044311498.1 0 0 0 0 29 NA NA NA NA NA NA 17294 XM_029330230.2 8 75 13 60 101 O18870 1.53e-22 Survival motor neuron protein Bos taurus (Bovine) DNA-templated transcription termination [GO:0006353]; nervous system development [GO:0007399]; spliceosomal snRNP assembly [GO:0000387] GO:0000387; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006353; GO:0007399; GO:0015030; GO:0030018; GO:0030424; GO:0032797; GO:0034719; GO:0036464; GO:0043005; GO:0043204; GO:0097504 17295 XM_044307485.1 2419 1072 1390 3088 2433 O75445 0 Usherin (Usher syndrome type IIa protein) (Usher syndrome type-2A protein) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear receptor cell differentiation [GO:0060113]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0001917; GO:0002141; GO:0002142; GO:0005518; GO:0005576; GO:0005604; GO:0005737; GO:0007601; GO:0007605; GO:0009887; GO:0009888; GO:0016324; GO:0016477; GO:0017022; GO:0032391; GO:0032421; GO:0034446; GO:0035315; GO:0036064; GO:0042491; GO:0042802; GO:0045184; GO:0045494; GO:0048496; GO:0050896; GO:0050953; GO:0051649; GO:0060113; GO:0060171; GO:1990075; GO:1990696 17296 XR_006397976.1 0 0 10 5 0 NA NA NA NA NA NA 17297 XR_006394897.1 9 0 0 0 1 NA NA NA NA NA NA 17298 XM_029347014.2 2 20 17 1 27 B0WC46 1.66e-87 Facilitated trehalose transporter Tret1 Culex quinquefasciatus (Southern house mosquito) (Culex pungens) trehalose transport [GO:0015771] GO:0005886; GO:0015574; GO:0015771; GO:0051119 17299 XR_006391647.1 2088 7366 2513 5417 6518 NA NA NA NA NA NA 17300 XM_029330614.2 32 13 21 34 36 Q06725 3.1e-85 Nuclear receptor subfamily 2 group F member 1-A (COUP transcription factor 1-A) (COUP-TFalpha-A) (zCOUP-TFI) (Seven-up related 44) (Svp[44]) (zSvp[44]) (Steroid receptor homolog SVP 44) Danio rerio (Zebrafish) (Brachydanio rerio) anatomical structure development [GO:0048856]; atrial cardiac muscle cell differentiation [GO:0055011]; cardiac atrium morphogenesis [GO:0003209]; cardiac muscle tissue development [GO:0048738]; cell differentiation [GO:0030154]; endothelial cell proliferation [GO:0001935]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; vasculature development [GO:0001944] GO:0000122; GO:0000978; GO:0001935; GO:0001944; GO:0003209; GO:0004879; GO:0005634; GO:0006357; GO:0008270; GO:0030154; GO:0045944; GO:0048738; GO:0048856; GO:0055011 17301 XM_029349546.2 13033 17414 6452 9177 7574 O35587 2.24e-83 Transmembrane emp24 domain-containing protein 10 (Protein TMED10) (21 kDa transmembrane-trafficking protein) (Integral membrane protein p23) (Transmembrane protein Tmp21) (p24 family protein delta-1) (p24delta1) Mesocricetus auratus (Golden hamster) COPI-coated vesicle budding [GO:0035964]; cytosol to ERGIC protein transport [GO:0106273]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886]; negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902960]; positive regulation of interleukin-1 production [GO:0032732]; positive regulation of protein secretion [GO:0050714]; protein localization to ERGIC [GO:0106272]; regulated exocytosis [GO:0045055]; regulation of amyloid-beta formation [GO:1902003]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] GO:0000139; GO:0005789; GO:0005793; GO:0005886; GO:0006886; GO:0006890; GO:0007030; GO:0008320; GO:0019905; GO:0030137; GO:0030140; GO:0030658; GO:0032732; GO:0033116; GO:0035964; GO:0042470; GO:0042589; GO:0045055; GO:0050714; GO:0070765; GO:0106272; GO:0106273; GO:1902003; GO:1902960 17302 XM_029331452.2 153 459 251 701 545 J7GQ11 6.83e-70 L-tyrosine decarboxylase (TDC) (EC 4.1.1.25) Levilactobacillus brevis (Lactobacillus brevis) carboxylic acid metabolic process [GO:0019752] GO:0004837; GO:0019752; GO:0030170; GO:0036468 17303 XM_029342738.2 135 94 61 110 13 Q6ZNA5 4.82e-36 Ferric-chelate reductase 1 (EC 1.-.-.-) (Stromal cell-derived receptor 2) (SDR-2) Homo sapiens (Human) cellular iron ion homeostasis [GO:0006879] GO:0006879; GO:0016020; GO:0016722; GO:0046872 17304 XM_029341623.2 876 550 330 567 357 Q9NW38 5.3e-116 E3 ubiquitin-protein ligase FANCL (EC 2.3.2.27) (Fanconi anemia group L protein) (Fanconi anemia-associated polypeptide of 43 kDa) (FAAP43) (RING-type E3 ubiquitin transferase FANCL) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; gamete generation [GO:0007276]; interstrand cross-link repair [GO:0036297]; protein monoubiquitination [GO:0006513]; regulation of cell population proliferation [GO:0042127] GO:0000785; GO:0004842; GO:0005634; GO:0005635; GO:0005654; GO:0005737; GO:0006281; GO:0006513; GO:0006974; GO:0007276; GO:0016604; GO:0031625; GO:0036297; GO:0042127; GO:0043231; GO:0043240; GO:0046872; GO:0061630 17305 XM_029351253.2 10910 16470 7342 11343 10529 Q8CFN2 9.4e-120 Cell division control protein 42 homolog (EC 3.6.5.2) Rattus norvegicus (Rat) actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; cardiac conduction system development [GO:0003161]; cardiac neural crest cell migration involved in outflow tract morphogenesis [GO:0003253]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cellular response to type II interferon [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; embryonic heart tube development [GO:0035050]; endocytosis [GO:0006897]; endothelin receptor signaling pathway involved in heart process [GO:0086101]; establishment of cell polarity [GO:0030010]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment of localization in cell [GO:0051649]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; establishment or maintenance of cell polarity [GO:0007163]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; modification of synaptic structure [GO:0099563]; negative regulation of protein-containing complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; nucleus localization [GO:0051647]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pinocytosis [GO:0048549]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of exocytosis [GO:0017157]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of postsynapse organization [GO:0099175]; regulation of protein binding [GO:0043393]; regulation of stress fiber assembly [GO:0051492]; response to glucose [GO:0009749]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; viral RNA genome replication [GO:0039694] GO:0000139; GO:0000322; GO:0002040; GO:0003161; GO:0003253; GO:0003924; GO:0003925; GO:0005525; GO:0005737; GO:0005815; GO:0005829; GO:0005886; GO:0005911; GO:0006468; GO:0006897; GO:0006911; GO:0007015; GO:0007030; GO:0007088; GO:0007097; GO:0007163; GO:0007229; GO:0008104; GO:0009749; GO:0010591; GO:0010592; GO:0016020; GO:0017119; GO:0017157; GO:0019901; GO:0030010; GO:0030036; GO:0030141; GO:0030175; GO:0030307; GO:0030335; GO:0030496; GO:0030742; GO:0031252; GO:0031256; GO:0031258; GO:0031274; GO:0031333; GO:0031435; GO:0031996; GO:0032427; GO:0032467; GO:0032488; GO:0032991; GO:0034191; GO:0034329; GO:0034332; GO:0035050; GO:0035088; GO:0036336; GO:0036464; GO:0038189; GO:0039694; GO:0042802; GO:0042995; GO:0043005; GO:0043025; GO:0043085; GO:0043197; GO:0043393; GO:0043410; GO:0043525; GO:0043552; GO:0045177; GO:0045198; GO:0045335; GO:0045740; GO:0046330; GO:0046847; GO:0048549; GO:0048664; GO:0051233; GO:0051489; GO:0051491; GO:0051492; GO:0051496; GO:0051647; GO:0051649; GO:0051683; GO:0051835; GO:0051988; GO:0060047; GO:0060501; GO:0060661; GO:0060997; GO:0061630; GO:0071346; GO:0071944; GO:0072384; GO:0072686; GO:0086101; GO:0090135; GO:0090316; GO:0098685; GO:0098978; GO:0099159; GO:0099175; GO:0099563; GO:1900026; GO:2000251 17306 XM_029341482.2 3185 2828 2405 2962 4008 Q6INE3 2.79e-67 Toll-interacting protein B Xenopus laevis (African clawed frog) autophagy [GO:0006914]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; phosphorylation [GO:0016310] GO:0005737; GO:0006914; GO:0006954; GO:0016310; GO:0043130; GO:0045087 17307 XM_029337304.2 74 43 37 32 10 B4E2M5 3.69e-31 Ankyrin repeat domain-containing protein 66 Homo sapiens (Human) NA NA 17308 XM_029328171.2 1456 653 861 1317 1087 NA NA NA NA NA NA 17309 XM_029334997.2 12356 9764 3387 8123 2633 NA NA NA NA NA NA 17310 XM_044320448.1 892 930 486 666 441 Q56P28 1.38e-32 PRA1 family protein 3 (ADP-ribosylation factor-like protein 6-interacting protein 5) (ARL-6-interacting protein 5) (Aip-5) Sus scrofa (Pig) L-glutamate transmembrane transport [GO:0015813]; negative regulation of L-glutamate import across plasma membrane [GO:0002037]; negative regulation of transport [GO:0051051] GO:0002037; GO:0005789; GO:0005856; GO:0005886; GO:0015813; GO:0016020; GO:0051051 17311 XM_044319270.1 331 249 44 139 86 NA NA NA NA NA NA 17312 XM_044320827.1 27 40 223 21 62 NA NA NA NA NA NA 17313 XR_003824794.2 5 9 31 24 15 NA NA NA NA NA NA 17314 XM_029336559.2 1076 680 1802 2221 1898 Q29496 1.57e-107 Cytochrome P450 3A24 (EC 1.14.14.1) (CYPIIIA24) Ovis aries (Sheep) NA GO:0004497; GO:0005506; GO:0005789; GO:0020037; GO:0070330 17315 XR_003828619.2 180 102 85 378 184 NA NA NA NA NA NA 17316 XM_029329015.2 226 145 200 268 325 Q9Y573 3.91e-153 Actin-binding protein IPP (Intracisternal A particle-promoted polypeptide) (IPP) (Kelch-like protein 27) Homo sapiens (Human) NA GO:0003779; GO:0005737; GO:0015629 17317 XR_003828612.2 13 10 12 19 9 NA NA NA NA NA NA 17318 XM_044323817.1 0 0 26 0 0 NA NA NA NA NA NA 17319 XR_003827985.2 0 0 0 6497 1929 NA NA NA NA NA NA 17320 XR_006392417.1 11 0 0 3 0 NA NA NA NA NA NA 17321 XM_029341927.2 0 0 0 31 0 P97677 5.45e-84 Delta-like protein 1 (Drosophila Delta homolog 1) (Delta1) Rattus norvegicus (Rat) astrocyte development [GO:0014002]; auditory receptor cell fate commitment [GO:0009912]; cell fate determination [GO:0001709]; cell-cell signaling [GO:0007267]; cerebellar molecular layer formation [GO:0021688]; cerebellar Purkinje cell layer structural organization [GO:0021693]; clathrin-dependent endocytosis [GO:0072583]; compartment pattern specification [GO:0007386]; determination of left/right symmetry [GO:0007368]; endothelial tip cell fate specification [GO:0097102]; energy homeostasis [GO:0097009]; heart looping [GO:0001947]; inhibition of neuroepithelial cell differentiation [GO:0002085]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear development [GO:0048839]; lateral inhibition [GO:0046331]; left/right axis specification [GO:0070986]; loop of Henle development [GO:0072070]; marginal zone B cell differentiation [GO:0002315]; myeloid cell differentiation [GO:0030099]; negative regulation of cardiac muscle cell differentiation [GO:2000726]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal cell differentiation [GO:0045605]; negative regulation of epithelial cell differentiation [GO:0030857]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of inner ear auditory receptor cell differentiation [GO:0045608]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of Notch signaling pathway [GO:0045746]; nephron development [GO:0072006]; nervous system development [GO:0007399]; neuroepithelial cell differentiation [GO:0060563]; neuron differentiation [GO:0030182]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; Notch signaling pathway involved in arterial endothelial cell fate commitment [GO:0060853]; organ growth [GO:0035265]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endocytosis [GO:0045807]; positive regulation of gene expression [GO:0010628]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of skeletal muscle tissue growth [GO:0048633]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proximal tubule development [GO:0072014]; proximal/distal pattern formation [GO:0009954]; regulation of blood pressure [GO:0008217]; regulation of cell adhesion [GO:0030155]; regulation of cell division [GO:0051302]; regulation of growth [GO:0040008]; regulation of neurogenesis [GO:0050767]; regulation of skeletal muscle tissue growth [GO:0048631]; regulation of somitogenesis [GO:0014807]; regulation of vascular endothelial growth factor signaling pathway [GO:1900746]; retina development in camera-type eye [GO:0060041]; retina morphogenesis in camera-type eye [GO:0060042]; skeletal muscle tissue growth [GO:0048630]; skin epidermis development [GO:0098773]; somite specification [GO:0001757]; somitogenesis [GO:0001756]; spinal cord development [GO:0021510]; type B pancreatic cell development [GO:0003323] GO:0001709; GO:0001756; GO:0001757; GO:0001947; GO:0002085; GO:0002315; GO:0003323; GO:0005112; GO:0005509; GO:0005886; GO:0005912; GO:0007219; GO:0007267; GO:0007368; GO:0007386; GO:0007399; GO:0008217; GO:0008284; GO:0008285; GO:0009912; GO:0009954; GO:0010628; GO:0014002; GO:0014807; GO:0016324; GO:0021510; GO:0021688; GO:0021693; GO:0030099; GO:0030155; GO:0030182; GO:0030857; GO:0030957; GO:0031410; GO:0032693; GO:0034351; GO:0035265; GO:0040008; GO:0042491; GO:0045121; GO:0045596; GO:0045605; GO:0045608; GO:0045638; GO:0045662; GO:0045665; GO:0045746; GO:0045747; GO:0045807; GO:0045944; GO:0046331; GO:0048018; GO:0048630; GO:0048631; GO:0048633; GO:0048665; GO:0048839; GO:0050767; GO:0051302; GO:0060041; GO:0060042; GO:0060563; GO:0060853; GO:0070986; GO:0072006; GO:0072014; GO:0072070; GO:0072583; GO:0097009; GO:0097102; GO:0097110; GO:0097150; GO:0098773; GO:1900746; GO:1903672; GO:2000726 17322 XR_006394753.1 9 3 5 0 26 NA NA NA NA NA NA 17323 XR_006396467.1 29 7 19 57 141 NA NA NA NA NA NA 17324 XM_029336343.2 1017 927 531 815 698 NA NA NA NA NA NA 17325 XM_044313560.1 538 355 253 429 373 Q6ZTW0 3.61e-30 Tubulin polyglutamylase complex subunit 1 (PGs1) Homo sapiens (Human) adult behavior [GO:0030534]; chemical synaptic transmission [GO:0007268]; protein polyglutamylation [GO:0018095]; sperm axoneme assembly [GO:0007288]; vesicle localization [GO:0051648] GO:0005737; GO:0005813; GO:0005874; GO:0007268; GO:0007288; GO:0008017; GO:0018095; GO:0030424; GO:0030425; GO:0030534; GO:0031514; GO:0045202; GO:0051648; GO:0070740 17326 XR_006393433.1 3 49 10 20 49 NA NA NA NA NA NA 17327 XM_029330523.2 2538 1661 1214 1882 2322 Q9Z1K5 0 E3 ubiquitin-protein ligase ARIH1 (EC 2.3.2.31) (Protein ariadne-1 homolog) (ARI-1) (RING-type E3 ubiquitin transferase ARIH1) (UbcH7-binding protein) (UbcM4-interacting protein 77) (Ubiquitin-conjugating enzyme E2-binding protein 1) Mus musculus (Mouse) positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000151; GO:0000209; GO:0004842; GO:0005634; GO:0005654; GO:0005737; GO:0006511; GO:0008270; GO:0015030; GO:0016567; GO:0016604; GO:0019005; GO:0031462; GO:0031463; GO:0031464; GO:0031624; GO:0031625; GO:0032436; GO:0061630; GO:0097413 17328 XM_029331607.2 23 53 14 9 55 Q96FW1 2.18e-96 Ubiquitin thioesterase OTUB1 (EC 3.4.19.12) (Deubiquitinating enzyme OTUB1) (OTU domain-containing ubiquitin aldehyde-binding protein 1) (Otubain-1) (hOTU1) (Ubiquitin-specific-processing protease OTUB1) Homo sapiens (Human) adaptive immune response [GO:0002250]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; negative regulation of double-strand break repair [GO:2000780]; negative regulation of histone H2A K63-linked ubiquitination [GO:1901315]; protein K48-linked deubiquitination [GO:0071108] GO:0002250; GO:0004843; GO:0005634; GO:0005654; GO:0005829; GO:0006281; GO:0006974; GO:0019784; GO:0031625; GO:0043130; GO:0070062; GO:0071108; GO:1901315; GO:2000780 17329 XM_044309369.1 15 0 31 0 94 NA NA NA NA NA NA 17330 XM_044323324.1 192 294 455 437 555 Q6P5F6 1.25e-43 Zinc transporter ZIP10 (Solute carrier family 39 member 10) (Zrt- and Irt-like protein 10) (ZIP-10) Mus musculus (Mouse) cellular zinc ion homeostasis [GO:0006882]; negative regulation of B cell apoptotic process [GO:0002903]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of B cell receptor signaling pathway [GO:0050861]; positive regulation of protein tyrosine phosphatase activity [GO:1903615]; zinc ion import across plasma membrane [GO:0071578] GO:0002903; GO:0005385; GO:0005886; GO:0006882; GO:0030890; GO:0050861; GO:0071578; GO:1903615 17331 XM_044326991.1 10 13 0 0 4 NA NA NA NA NA NA 17332 XM_044322205.1 375 185 182 0 145 Q5F499 0 Dynamin-like 120 kDa protein, mitochondrial (EC 3.6.5.5) (Optic atrophy protein 1 homolog) [Cleaved into: Dynamin-like 120 kDa protein, form S1] Gallus gallus (Chicken) apoptotic process [GO:0006915]; GTP metabolic process [GO:0046039]; membrane tubulation [GO:0097749]; mitochondrial fusion [GO:0008053] GO:0003924; GO:0005525; GO:0005737; GO:0005743; GO:0005758; GO:0005874; GO:0006915; GO:0008017; GO:0008053; GO:0016020; GO:0031966; GO:0046039; GO:0070300; GO:0097749; GO:1901612 17333 XR_006393708.1 18 5 1 15 5 NA NA NA NA NA NA 17334 XM_029352051.2 8 0 5 0 0 Q9HC58 7.65e-73 Sodium/potassium/calcium exchanger 3 (Na(+)/K(+)/Ca(2+)-exchange protein 3) (Solute carrier family 24 member 3) Homo sapiens (Human) bone mineralization [GO:0030282]; calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; ion transport [GO:0006811]; negative regulation of gene expression [GO:0010629]; positive regulation of gene expression [GO:0010628]; potassium ion transmembrane transport [GO:0071805]; sodium ion transmembrane transport [GO:0035725]; transport across blood-brain barrier [GO:0150104] GO:0005262; GO:0005886; GO:0006811; GO:0006874; GO:0008273; GO:0010628; GO:0010629; GO:0015293; GO:0030282; GO:0035725; GO:0070588; GO:0071805; GO:0071944; GO:0150104 17335 XM_029352051.2 8 0 5 0 0 Q9HC58 2.1e-60 Sodium/potassium/calcium exchanger 3 (Na(+)/K(+)/Ca(2+)-exchange protein 3) (Solute carrier family 24 member 3) Homo sapiens (Human) bone mineralization [GO:0030282]; calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; ion transport [GO:0006811]; negative regulation of gene expression [GO:0010629]; positive regulation of gene expression [GO:0010628]; potassium ion transmembrane transport [GO:0071805]; sodium ion transmembrane transport [GO:0035725]; transport across blood-brain barrier [GO:0150104] GO:0005262; GO:0005886; GO:0006811; GO:0006874; GO:0008273; GO:0010628; GO:0010629; GO:0015293; GO:0030282; GO:0035725; GO:0070588; GO:0071805; GO:0071944; GO:0150104 17336 XM_029348186.2 59 0 0 0 22 Q6P7A2 0 Ubiquitin conjugation factor E4 A (EC 2.3.2.27) (RING-type E3 ubiquitin transferase E4 A) Rattus norvegicus (Rat) protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0000151; GO:0000209; GO:0005634; GO:0005737; GO:0016567; GO:0030433; GO:0034450; GO:0061630 17337 XM_029349312.2 1329 389 285 258 0 Q15075 3.4e-50 Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2) Homo sapiens (Human) chemical synaptic transmission, postsynaptic [GO:0099565]; early endosome to late endosome transport [GO:0045022]; endocytosis [GO:0006897]; modulation by host of viral process [GO:0044788]; synaptic vesicle to endosome fusion [GO:0016189]; vesicle fusion [GO:0006906] GO:0005516; GO:0005545; GO:0005737; GO:0005769; GO:0005829; GO:0005969; GO:0006897; GO:0006906; GO:0008270; GO:0016020; GO:0016189; GO:0019897; GO:0030742; GO:0031901; GO:0042803; GO:0044308; GO:0044788; GO:0045022; GO:0070062; GO:0098685; GO:0098794; GO:0098978; GO:0099565 17338 XM_029335486.2 3062 4279 2982 2228 2414 NA NA NA NA NA NA 17339 XM_044320536.1 0 69 0 83 41 A0A1L8FZ98 8.29e-66 Peroxisome biogenesis factor 2 (EC 2.3.2.27) (EC 2.3.2.36) (Peroxin-2) Xenopus laevis (African clawed frog) pexophagy [GO:0000425]; protein import into peroxisome matrix, receptor recycling [GO:0016562]; response to amino acid starvation [GO:1990928] GO:0000425; GO:0005778; GO:0016562; GO:0046872; GO:0061630; GO:1990928 17340 XM_044329286.1 1 4 8 11 15 NA NA NA NA NA NA 17341 XM_044322118.1 191 153 153 295 453 Q8CBF3 1.34e-157 Ephrin type-B receptor 1 (EC 2.7.10.1) Mus musculus (Mouse) angiogenesis [GO:0001525]; axon guidance [GO:0007411]; camera-type eye morphogenesis [GO:0048593]; cell chemotaxis [GO:0060326]; cell-substrate adhesion [GO:0031589]; central nervous system projection neuron axonogenesis [GO:0021952]; cranial nerve development [GO:0021545]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; ephrin receptor signaling pathway [GO:0048013]; establishment of cell polarity [GO:0030010]; hindbrain tangential cell migration [GO:0021934]; immunological synapse formation [GO:0001771]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of satellite cell differentiation [GO:1902725]; negative regulation of skeletal muscle satellite cell proliferation [GO:1902723]; neural precursor cell proliferation [GO:0061351]; neurogenesis [GO:0022008]; optic nerve morphogenesis [GO:0021631]; positive regulation of kinase activity [GO:0033674]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of neuron death [GO:1901214]; retinal ganglion cell axon guidance [GO:0031290]; skeletal muscle satellite cell activation [GO:0014719]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0001525; GO:0001771; GO:0004713; GO:0004714; GO:0005005; GO:0005524; GO:0005737; GO:0005783; GO:0005829; GO:0005886; GO:0007169; GO:0007411; GO:0008046; GO:0014719; GO:0016020; GO:0021545; GO:0021631; GO:0021934; GO:0021952; GO:0022008; GO:0030010; GO:0030424; GO:0030425; GO:0031290; GO:0031589; GO:0031901; GO:0032433; GO:0033674; GO:0043005; GO:0043235; GO:0044877; GO:0045121; GO:0046328; GO:0046777; GO:0048013; GO:0048593; GO:0050804; GO:0050965; GO:0051965; GO:0060326; GO:0060996; GO:0060997; GO:0061351; GO:0070372; GO:0098978; GO:1901214; GO:1902723; GO:1902725 17342 XM_044326776.1 17 0 15 14 2 NA NA NA NA NA NA 17343 XM_044322001.1 0 295 14 59 156 A2VDD2 2.01e-22 Dynein light chain Tctex-type 5-B (Tctex1 domain-containing protein 1-B) Xenopus laevis (African clawed frog) NA NA 17344 XM_029334460.2 191 111 57 199 214 P09875 5.08e-95 UDP-glucuronosyltransferase 2B1 (UDPGT 2B1) (UGT2B1) (EC 2.4.1.17) (UDPGTr-2) Rattus norvegicus (Rat) biphenyl catabolic process [GO:0070980]; cellular glucuronidation [GO:0052695]; cellular response to ethanol [GO:0071361]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to growth hormone stimulus [GO:0071378]; cellular response to testosterone stimulus [GO:0071394]; estrogen metabolic process [GO:0008210]; protein glucuronidation [GO:0018411]; protein O-glucuronidation [GO:0018412]; response to lipopolysaccharide [GO:0032496]; xenobiotic metabolic process [GO:0006805] GO:0005789; GO:0006805; GO:0008210; GO:0015020; GO:0018411; GO:0018412; GO:0032496; GO:0043231; GO:0052695; GO:0070980; GO:0071361; GO:0071378; GO:0071385; GO:0071394 17345 XM_044326312.1 3800 3019 2725 4035 4048 Q9Y297 0 F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit) Homo sapiens (Human) branching involved in mammary gland duct morphogenesis [GO:0060444]; cellular response to organic cyclic compound [GO:0071407]; mammary gland epithelial cell proliferation [GO:0033598]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of smoothened signaling pathway [GO:0045879]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of proteolysis [GO:0045862]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein dephosphorylation [GO:0006470]; protein destabilization [GO:0031648]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of cell cycle [GO:0051726]; regulation of circadian rhythm [GO:0042752]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of proteasomal protein catabolic process [GO:0061136]; rhythmic process [GO:0048511]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; signal transduction [GO:0007165]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt signaling pathway [GO:0016055] GO:0000209; GO:0005654; GO:0005829; GO:0006470; GO:0006511; GO:0007165; GO:0008013; GO:0016055; GO:0016567; GO:0016874; GO:0019005; GO:0031146; GO:0031648; GO:0033598; GO:0042752; GO:0042753; GO:0043122; GO:0043161; GO:0043433; GO:0045309; GO:0045862; GO:0045879; GO:0045892; GO:0045893; GO:0046983; GO:0048511; GO:0051726; GO:0060444; GO:0060828; GO:0061136; GO:0061630; GO:0070936; GO:0071407; GO:1904668; GO:1990756; GO:1990757 17346 XR_006397146.1 15 1 3 0 36 NA NA NA NA NA NA 17347 XM_029337793.2 0 15 0 6 0 B3EWY9 5.88e-28 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 17348 XM_029337793.2 0 15 0 6 0 B3EWY9 8.24e-24 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 17349 XM_044315961.1 93 12 33 12 107 NA NA NA NA NA NA 17350 XR_006396459.1 16 12 3 26 18 NA NA NA NA NA NA 17351 XM_029334827.2 124 32 53 35 51 NA NA NA NA NA NA 17352 XM_044319432.1 0 3 23 3 0 Q94K49 1.64e-24 Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1 (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) epigenetic regulation of gene expression [GO:0040029] GO:0003682; GO:0004518; GO:0005634; GO:0035098; GO:0035102; GO:0040029; GO:0046872 17353 XM_044329108.1 76 145 186 201 177 NA NA NA NA NA NA 17354 XM_044328294.1 79 20 93 104 215 NA NA NA NA NA NA 17355 XM_044325262.1 424 412 243 520 295 Q9UK61 1e-23 Protein TASOR (CTCL tumor antigen se89-1) (Retinoblastoma-associated protein RAP140) (Transgene activation suppressor protein) Homo sapiens (Human) anterior/posterior axis specification, embryo [GO:0008595]; mesodermal to mesenchymal transition involved in gastrulation [GO:0060809]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; positive regulation of DNA methylation-dependent heterochromatin formation [GO:0090309]; protein localization to heterochromatin [GO:0097355] GO:0000792; GO:0003682; GO:0003723; GO:0005654; GO:0008595; GO:0045814; GO:0045869; GO:0060809; GO:0090309; GO:0097355 17356 XR_006396225.1 2951 326 264 1437 483 NA NA NA NA NA NA 17357 XM_029328644.2 0 53 67 67 40 Q62687 2.64e-153 Sodium-dependent neutral amino acid transporter B(0)AT3 (Renal osmotic stress-induced Na-Cl organic solute cotransporter) (ROSIT) (Sodium- and chloride-dependent transporter XTRP2) (Solute carrier family 6 member 18) (System B(0) neutral amino acid transporter AT3) Rattus norvegicus (Rat) amino acid transmembrane transport [GO:0003333]; hyperosmotic response [GO:0006972]; neurotransmitter transport [GO:0006836]; neutral amino acid transport [GO:0015804]; renal amino acid absorption [GO:1990297]; response to osmotic stress [GO:0006970]; sodium ion transmembrane transport [GO:0035725] GO:0003333; GO:0005886; GO:0006836; GO:0006970; GO:0006972; GO:0015175; GO:0015804; GO:0016324; GO:0031526; GO:0035725; GO:0140931; GO:1990297 17358 XM_029333106.2 556 374 226 479 363 Q8WYR4 4.1e-71 Radial spoke head 1 homolog (Cancer/testis antigen 79) (CT79) (Male meiotic metaphase chromosome-associated acidic protein) (Meichroacidin) (Testis-specific gene A2 protein) Homo sapiens (Human) axoneme assembly [GO:0035082]; meiotic cell cycle [GO:0051321]; spermatid development [GO:0007286] GO:0000794; GO:0001520; GO:0005634; GO:0005829; GO:0007286; GO:0031514; GO:0035082; GO:0051321; GO:0072687 17359 XM_044322824.1 146 98 87 208 88 G1TFM5 8.91e-128 NA NA NA NA 17360 XM_029329118.2 39 1 21 36 20 NA NA NA NA NA NA 17361 XM_029332866.2 196 188 0 200 0 NA NA NA NA NA NA 17362 XM_029342126.2 22 639 0 1 335 Q14692 0 Ribosome biogenesis protein BMS1 homolog (Ribosome assembly protein BMS1 homolog) Homo sapiens (Human) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000479]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462] GO:0000462; GO:0000479; GO:0003723; GO:0003924; GO:0005524; GO:0005525; GO:0005654; GO:0005694; GO:0005730; GO:0030686; GO:0034511 17363 XM_029342126.2 22 639 0 1 335 Q14692 1.03e-73 Ribosome biogenesis protein BMS1 homolog (Ribosome assembly protein BMS1 homolog) Homo sapiens (Human) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000479]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462] GO:0000462; GO:0000479; GO:0003723; GO:0003924; GO:0005524; GO:0005525; GO:0005654; GO:0005694; GO:0005730; GO:0030686; GO:0034511 17364 XM_029342126.2 22 639 0 1 335 Q14692 3.14e-41 Ribosome biogenesis protein BMS1 homolog (Ribosome assembly protein BMS1 homolog) Homo sapiens (Human) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000479]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462] GO:0000462; GO:0000479; GO:0003723; GO:0003924; GO:0005524; GO:0005525; GO:0005654; GO:0005694; GO:0005730; GO:0030686; GO:0034511 17365 XM_044308177.1 13 1 4 7 14 Q9M2U3 1.31e-24 Protein ALP1-like (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) NA GO:0000118; GO:0004518; GO:0046872 17366 XR_006391547.1 29 0 17 25 0 NA NA NA NA NA NA 17367 XM_044314108.1 487 506 580 403 357 Q9NX74 1.86e-160 tRNA-dihydrouridine(20) synthase [NAD(P)+]-like (EC 1.3.1.91) (Dihydrouridine synthase 2) (Up-regulated in lung cancer protein 8) (URLC8) (tRNA-dihydrouridine synthase 2-like) (hDUS2) Homo sapiens (Human) negative regulation of cell death [GO:0060548]; tRNA dihydrouridine synthesis [GO:0002943] GO:0000049; GO:0002943; GO:0003725; GO:0004860; GO:0005737; GO:0005783; GO:0005829; GO:0010181; GO:0017150; GO:0050660; GO:0060548; GO:0070402; GO:0102264 17368 XM_029343355.2 1941 2008 1207 2291 1213 Q9UIF3 7.85e-139 Tektin-2 (Tektin-t) (Testicular tektin) (Testicular tektin B1-like protein) (TEKTB1) (Tektin-B1) Homo sapiens (Human) cilium assembly [GO:0060271]; cilium movement involved in cell motility [GO:0060294]; flagellated sperm motility [GO:0030317]; inner dynein arm assembly [GO:0036159] GO:0005634; GO:0005815; GO:0005879; GO:0015630; GO:0030317; GO:0031514; GO:0036159; GO:0060271; GO:0060294 17369 XM_044319755.1 190 165 214 125 184 Q5BIM1 2.35e-52 Tripartite motif-containing protein 45 Bos taurus (Bovine) bone development [GO:0060348]; positive regulation of DNA-templated transcription [GO:0045893] GO:0000785; GO:0004842; GO:0005654; GO:0005829; GO:0008270; GO:0045171; GO:0045893; GO:0060348 17370 XM_044318269.1 24 17 15 74 50 NA NA NA NA NA NA 17371 XM_044328890.1 10 2 10 3 40 NA NA NA NA NA NA 17372 XM_029338894.2 110 255 0 0 184 Q9NUD9 1.77e-73 GPI mannosyltransferase 2 (EC 2.4.1.-) (GPI mannosyltransferase II) (GPI-MT-II) (Phosphatidylinositol-glycan biosynthesis class V protein) (PIG-V) Homo sapiens (Human) GPI anchor biosynthetic process [GO:0006506]; preassembly of GPI anchor in ER membrane [GO:0016254] GO:0000009; GO:0000030; GO:0004376; GO:0005789; GO:0006506; GO:0016020; GO:0016254; GO:0031501 17373 XR_003825092.2 13 18 30 17 86 NA NA NA NA NA NA 17374 XM_044321756.1 0 19 0 0 0 NA NA NA NA NA NA 17375 XM_044315960.1 4 1 0 0 7 NA NA NA NA NA NA 17376 XM_044315962.1 0 59 0 18 72 B8VIU6 6.4e-48 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 17377 XM_029336761.2 21 20 44 23 35 D3Z5L6 3.04e-60 MFS-type transporter SLC18B1 (Solute carrier family 18 member B1) (Vesicular polyamine transporter) (VPAT) Mus musculus (Mouse) serotonin transport [GO:0006837]; serotonin uptake [GO:0051610]; spermidine transport [GO:0015848]; spermine transport [GO:0000296] GO:0000296; GO:0006837; GO:0015311; GO:0015312; GO:0015848; GO:0022857; GO:0030667; GO:0030672; GO:0051610 17378 XM_029328867.2 134 77 73 18 380 Q3ZBG9 2.75e-97 Phospholipid scramblase 2 (PL scramblase 2) (Ca(2+)-dependent phospholipid scramblase 2) Bos taurus (Bovine) plasma membrane phospholipid scrambling [GO:0017121] GO:0005886; GO:0017121; GO:0017128; GO:0046872 17379 XM_044323928.1 7 5 5 0 2 Q91ZV3 1.57e-22 Discoidin, CUB and LCCL domain-containing protein 2 (Endothelial and smooth muscle cell-derived neuropilin-like protein) Mus musculus (Mouse) negative regulation of cell growth [GO:0030308]; wound healing [GO:0042060] GO:0005886; GO:0009986; GO:0030308; GO:0038023; GO:0042060 17380 XM_044311338.1 37 15 14 17 9 NA NA NA NA NA NA 17381 XM_044318661.1 0 81 0 190 0 O75899 9.91e-72 Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51) (HG20) Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway [GO:0007186]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; neuron-glial cell signaling [GO:0150099]; synaptic transmission, GABAergic [GO:0051932] GO:0004888; GO:0004965; GO:0005737; GO:0005886; GO:0007186; GO:0007193; GO:0007194; GO:0007214; GO:0007268; GO:0038039; GO:0043005; GO:0045211; GO:0046982; GO:0051932; GO:0150099; GO:1902710; GO:1902712 17382 XM_029329201.2 641 486 347 545 753 Q8NEF3 1.43e-81 Coiled-coil domain-containing protein 112 (Mutated in bladder cancer protein 1) Homo sapiens (Human) NA GO:0005737; GO:0034451 17383 XM_029358060.2 49 0 19 11 80 NA NA NA NA NA NA 17384 XM_044318819.1 7030 5026 6 1513 149 Q8IVV2 8.69e-102 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 17385 XM_044318819.1 7030 5026 6 1513 149 Q8IVV2 1.45e-99 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 17386 XM_044318819.1 7030 5026 6 1513 149 Q8IVV2 2.06e-98 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 17387 XM_044318819.1 7030 5026 6 1513 149 Q8IVV2 1.14e-95 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 17388 XM_044318819.1 7030 5026 6 1513 149 Q8IVV2 5.74e-88 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 17389 XM_044318819.1 7030 5026 6 1513 149 Q8IVV2 3.01e-82 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 17390 XM_044318819.1 7030 5026 6 1513 149 Q8IVV2 4.11e-80 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 17391 XM_044318819.1 7030 5026 6 1513 149 Q8IVV2 5.35e-73 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 17392 XM_044317812.1 1073 1015 680 622 668 A7STV9 1.33e-90 Structure-specific endonuclease subunit SLX1 homolog (EC 3.1.-.-) Nematostella vectensis (Starlet sea anemone) double-strand break repair via homologous recombination [GO:0000724] GO:0000724; GO:0008821; GO:0017108; GO:0033557; GO:0046872 17393 XR_006396530.1 30 13 0 20 26 NA NA NA NA NA NA 17394 XM_029344756.2 0 0 0 18 0 P56718 3.12e-27 Orexin/Hypocretin receptor type 1 (Hypocretin receptor type 1) (Orexin receptor type 1) (Ox-1-R) (Ox1-R) (Ox1R) Rattus norvegicus (Rat) feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0004930; GO:0005886; GO:0007186; GO:0007218; GO:0007631; GO:0016499; GO:0017046; GO:0051480; GO:0070374 17395 XM_029332618.2 3622 1754 1428 1725 1506 P53634 8.9e-176 Dipeptidyl peptidase 1 (EC 3.4.14.1) (Cathepsin C) (Cathepsin J) (Dipeptidyl peptidase I) (DPP-I) (DPPI) (Dipeptidyl transferase) [Cleaved into: Dipeptidyl peptidase 1 exclusion domain chain (Dipeptidyl peptidase I exclusion domain chain); Dipeptidyl peptidase 1 heavy chain (Dipeptidyl peptidase I heavy chain); Dipeptidyl peptidase 1 light chain (Dipeptidyl peptidase I light chain)] Homo sapiens (Human) aging [GO:0007568]; immune response [GO:0006955]; negative regulation of myelination [GO:0031642]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of proteolysis involved in protein catabolic process [GO:1903052]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; response to organic substance [GO:0010033]; T cell mediated cytotoxicity [GO:0001913] GO:0001913; GO:0004197; GO:0004252; GO:0005576; GO:0005615; GO:0005654; GO:0005764; GO:0005788; GO:0005794; GO:0005813; GO:0006508; GO:0006955; GO:0007568; GO:0008234; GO:0008239; GO:0010033; GO:0016020; GO:0016505; GO:0019902; GO:0030134; GO:0031404; GO:0031642; GO:0033116; GO:0035578; GO:0042802; GO:0043231; GO:0043621; GO:0051087; GO:0051603; GO:0062023; GO:0070062; GO:1903052; GO:1903980; GO:2001235 17396 XM_044317183.1 822 1134 969 1395 1189 Q6AYK5 4.1e-56 Cell growth-regulating nucleolar protein Rattus norvegicus (Rat) erythrocyte development [GO:0048821]; innate immune response [GO:0045087]; negative regulation of innate immune response [GO:0045824]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of phagocytosis [GO:0050766]; positive regulation of transcription by RNA polymerase I [GO:0045943]; rRNA processing [GO:0006364] GO:0000122; GO:0001750; GO:0003677; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0006364; GO:0042802; GO:0045087; GO:0045824; GO:0045943; GO:0046872; GO:0048821; GO:0050766; GO:0140297; GO:0140416 17397 XM_029324248.2 0 96 153 37 35 Q5PQ23 1.01e-83 Outer dense fiber protein 2 (Cenexin) (Outer dense fiber of sperm tails protein 2) Xenopus laevis (African clawed frog) cell differentiation [GO:0030154]; spermatogenesis [GO:0007283] GO:0000922; GO:0005737; GO:0005814; GO:0005874; GO:0007283; GO:0030154; GO:0036126 17398 XR_003827172.2 8 1 0 3 4 NA NA NA NA NA NA 17399 XM_029330112.2 0 360 0 0 0 Q14155 3.06e-126 Rho guanine nucleotide exchange factor 7 (Beta-Pix) (COOL-1) (PAK-interacting exchange factor beta) (p85) Homo sapiens (Human) ephrin receptor signaling pathway [GO:0048013]; focal adhesion assembly [GO:0048041]; Golgi organization [GO:0007030]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; negative regulation of microtubule nucleation [GO:1905833]; nervous system development [GO:0007399]; positive regulation of apoptotic process [GO:0043065]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of GTPase activity [GO:0043547]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of GTP binding [GO:1904424]; signal transduction [GO:0007165] GO:0001726; GO:0005085; GO:0005737; GO:0005813; GO:0005829; GO:0005925; GO:0005938; GO:0007030; GO:0007165; GO:0007399; GO:0010763; GO:0019901; GO:0030027; GO:0030032; GO:0032991; GO:0035556; GO:0043005; GO:0043015; GO:0043025; GO:0043065; GO:0043547; GO:0048013; GO:0048041; GO:0097431; GO:0098794; GO:1900026; GO:1904424; GO:1905833; GO:2000394 17400 XM_044313456.1 0 0 0 0 9 NA NA NA NA NA NA 17401 XM_029343458.2 6 9 0 0 0 NA NA NA NA NA NA 17402 XM_029348541.2 2198 1922 1126 1855 1139 P25324 2.59e-52 Thiosulfate sulfurtransferase (EC 2.8.1.1) (Rhodanese) Gallus gallus (Chicken) rRNA import into mitochondrion [GO:0035928]; rRNA transport [GO:0051029]; transsulfuration [GO:0019346] GO:0004792; GO:0005739; GO:0005759; GO:0008097; GO:0019346; GO:0035928; GO:0051029 17403 XM_044312548.1 0 44 0 0 0 Q8K3P0 3e-72 Short-chain dehydrogenase/reductase family 9C member 7 (EC 1.1.1.-) (Orphan short-chain dehydrogenase/reductase) (SDR-O) (RDH-S) Mus musculus (Mouse) retinol metabolic process [GO:0042572]; steroid metabolic process [GO:0008202] GO:0004745; GO:0005737; GO:0008202; GO:0016491; GO:0042572; GO:0043231 17404 XM_029339394.2 41 0 0 0 0 Q9SVG0 2.62e-63 Amino acid transporter AVT3C (AtAvt3C) (Aromatic and neutral amino acid transporter-like protein 2) Arabidopsis thaliana (Mouse-ear cress) amino acid transmembrane transport [GO:0003333]; neutral amino acid transport [GO:0015804] GO:0003333; GO:0005774; GO:0015175; GO:0015179; GO:0015804 17405 XM_044328541.1 66 90 102 42 0 A0NLY7 6.01e-25 Isatin hydrolase (EC 3.5.2.20) (Isatin amidohydrolase) (Isatin hydrolase isoform b) (IH-b) Roseibium aggregatum (strain ATCC 25650 / DSM 13394 / JCM 20685 / NBRC 16684 / NCIMB 2208 / IAM 12614 / B1) (Stappia aggregata) tryptophan catabolic process to kynurenine [GO:0019441] GO:0004061; GO:0016812; GO:0019441; GO:0030145 17406 XM_029334478.2 0 299 0 464 1109 Q8R4G6 0 Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (EC 2.4.1.155) (Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase) (GlcNAc-T V) (GNT-V) (Mannoside acetylglucosaminyltransferase 5) (N-acetylglucosaminyl-transferase V) [Cleaved into: Secreted alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (Secreted beta-1,6-N-acetylglucosaminyltransferase V) (Secreted GNT-V)] Mus musculus (Mouse) negative regulation of protein tyrosine phosphatase activity [GO:1903614]; positive regulation of cell migration [GO:0030335]; positive regulation of receptor signaling pathway via STAT [GO:1904894]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279] GO:0000139; GO:0004864; GO:0005576; GO:0005794; GO:0006487; GO:0008375; GO:0016020; GO:0016757; GO:0018279; GO:0030144; GO:0030145; GO:0030335; GO:0043204; GO:1903614; GO:1904894 17407 XM_029357258.2 0 86 0 0 145 NA NA NA NA NA NA 17408 XM_044314145.1 73 31 31 32 65 NA NA NA NA NA NA 17409 XM_044319370.1 46 83 105 117 117 Q7Z494 2.6e-49 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 17410 XM_044319370.1 46 83 105 117 117 Q7Z494 1.87e-39 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 17411 XM_044319370.1 46 83 105 117 117 Q7Z494 2.87e-37 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 17412 XM_029340130.2 2849 1964 1613 1733 899 Q9CVD2 3.84e-73 Ataxin-3 (EC 3.4.19.12) (Machado-Joseph disease protein 1 homolog) Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; cellular response to heat [GO:0034605]; cellular response to misfolded protein [GO:0071218]; exploration behavior [GO:0035640]; histone modification [GO:0016570]; intermediate filament cytoskeleton organization [GO:0045104]; microtubule cytoskeleton organization [GO:0000226]; monoubiquitinated protein deubiquitination [GO:0035520]; positive regulation of ERAD pathway [GO:1904294]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; protein localization to cytosolic proteasome complex involved in ERAD pathway [GO:1904379]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; regulation of cell-substrate adhesion [GO:0010810]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000226; GO:0000977; GO:0001222; GO:0004407; GO:0004843; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005759; GO:0005789; GO:0005829; GO:0005886; GO:0006511; GO:0006515; GO:0010810; GO:0016570; GO:0016579; GO:0030036; GO:0031625; GO:0031966; GO:0034605; GO:0035520; GO:0035640; GO:0042405; GO:0042802; GO:0042826; GO:0043161; GO:0045104; GO:0051117; GO:0061578; GO:0070536; GO:0071108; GO:0071218; GO:1904294; GO:1904379; GO:1990380 17413 XM_029332187.2 1769 1076 1009 1460 1709 Q6PFD9 0 Nuclear pore complex protein Nup98-Nup96 (EC 3.4.21.-) [Cleaved into: Nuclear pore complex protein Nup98 (98 kDa nucleoporin) (Nucleoporin Nup98) (Nup98); Nuclear pore complex protein Nup96 (96 kDa nucleoporin) (Nucleoporin Nup96) (Nup96)] Mus musculus (Mouse) mRNA transport [GO:0051028]; nuclear pore complex assembly [GO:0051292]; nucleocytoplasmic transport [GO:0006913]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508] GO:0000776; GO:0003713; GO:0003729; GO:0005634; GO:0005635; GO:0005643; GO:0005654; GO:0006508; GO:0006606; GO:0006913; GO:0008139; GO:0008236; GO:0016604; GO:0017056; GO:0031080; GO:0031965; GO:0034399; GO:0042277; GO:0042405; GO:0044615; GO:0048026; GO:0051028; GO:0051292; GO:1990841; GO:1990904 17414 XM_029332187.2 1769 1076 1009 1460 1709 Q6PFD9 3.89e-23 Nuclear pore complex protein Nup98-Nup96 (EC 3.4.21.-) [Cleaved into: Nuclear pore complex protein Nup98 (98 kDa nucleoporin) (Nucleoporin Nup98) (Nup98); Nuclear pore complex protein Nup96 (96 kDa nucleoporin) (Nucleoporin Nup96) (Nup96)] Mus musculus (Mouse) mRNA transport [GO:0051028]; nuclear pore complex assembly [GO:0051292]; nucleocytoplasmic transport [GO:0006913]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508] GO:0000776; GO:0003713; GO:0003729; GO:0005634; GO:0005635; GO:0005643; GO:0005654; GO:0006508; GO:0006606; GO:0006913; GO:0008139; GO:0008236; GO:0016604; GO:0017056; GO:0031080; GO:0031965; GO:0034399; GO:0042277; GO:0042405; GO:0044615; GO:0048026; GO:0051028; GO:0051292; GO:1990841; GO:1990904 17415 XM_044325420.1 193 15 0 34 0 NA NA NA NA NA NA 17416 XR_006395859.1 31 9 61 161 60 NA NA NA NA NA NA 17417 XM_029329862.2 414 47 365 454 374 P20072 1.09e-70 Annexin A7 (Annexin VII) (Annexin-7) (Synexin) Bos taurus (Bovine) NA GO:0005509; GO:0005544; GO:0005634; GO:0005737; GO:0042584 17418 XM_044328619.1 225 208 337 118 137 Q80VW5 1.01e-106 Whirlin Mus musculus (Mouse) auditory receptor cell stereocilium organization [GO:0060088]; cerebellar Purkinje cell layer formation [GO:0021694]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; inner ear receptor cell differentiation [GO:0060113]; inner ear receptor cell stereocilium organization [GO:0060122]; paranodal junction maintenance [GO:1990227]; positive regulation of gene expression [GO:0010628]; retina homeostasis [GO:0001895]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605] GO:0001895; GO:0001917; GO:0002141; GO:0002142; GO:0005737; GO:0005829; GO:0005884; GO:0005886; GO:0005929; GO:0007605; GO:0010628; GO:0016020; GO:0019904; GO:0021694; GO:0030426; GO:0032391; GO:0032420; GO:0032421; GO:0032426; GO:0036064; GO:0042802; GO:0043005; GO:0043025; GO:0043198; GO:0044303; GO:0045184; GO:0048471; GO:0050910; GO:0050953; GO:0051649; GO:0060088; GO:0060113; GO:0060122; GO:0097440; GO:0098793; GO:0098794; GO:1990075; GO:1990227; GO:1990696 17419 XM_029338060.2 858 531 246 441 755 Q8BUG5 2.48e-96 Calcyphosin-2 (Calcyphosine-2) Mus musculus (Mouse) NA GO:0005509 17420 XM_044312331.1 3 41 49 78 55 NA NA NA NA NA NA 17421 XM_029351252.2 1494 1684 733 1028 480 NA NA NA NA NA NA 17422 XM_029335403.2 894 1392 727 927 409 NA NA NA NA NA NA 17423 XM_044308648.1 0 0 0 46 0 NA NA NA NA NA NA 17424 XM_029335425.2 90 133 28 45 82 NA NA NA NA NA NA 17425 XM_029332926.2 5181 4882 3049 5600 5405 P92177 7.26e-93 14-3-3 protein epsilon (Suppressor of Ras1 3-9) Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; cytoplasmic sequestering of transcription factor [GO:0042994]; determination of adult lifespan [GO:0008340]; DNA damage checkpoint signaling [GO:0000077]; germarium-derived oocyte fate determination [GO:0007294]; microtubule sliding [GO:0051012]; negative regulation of neuron projection arborization [GO:0150013]; oocyte microtubule cytoskeleton polarization [GO:0008103]; pole cell migration [GO:0007280]; positive regulation of growth [GO:0045927]; positive regulation of hippo signaling [GO:0035332]; positive regulation of Ras protein signal transduction [GO:0046579]; R8 cell fate commitment [GO:0007460]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of mitotic nuclear division [GO:0007088]; response to UV [GO:0009411]; signal transduction [GO:0007165]; wing disc dorsal/ventral pattern formation [GO:0048190] GO:0000077; GO:0001223; GO:0005634; GO:0005654; GO:0005694; GO:0005737; GO:0005813; GO:0005829; GO:0005886; GO:0007088; GO:0007165; GO:0007280; GO:0007294; GO:0007346; GO:0007411; GO:0007460; GO:0008103; GO:0008340; GO:0009411; GO:0035332; GO:0040008; GO:0042994; GO:0045172; GO:0045927; GO:0046579; GO:0046982; GO:0048190; GO:0050815; GO:0051012; GO:0150013 17426 XM_044327155.1 34 36 47 31 46 B8VIW9 6.8e-80 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 17427 XM_044327155.1 34 36 47 31 46 B8VIW9 6.8e-80 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 17428 XM_044327155.1 34 36 47 31 46 B8VIW9 4.34e-25 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 17429 XM_029352094.2 0 13 1 0 37 Q7RTR2 7.39e-39 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 17430 XR_003824599.2 40 25 46 38 146 NA NA NA NA NA NA 17431 XM_029332832.2 1251 1069 704 983 1023 Q8NE09 9.97e-96 Regulator of G-protein signaling 22 (RGS22) Homo sapiens (Human) negative regulation of signal transduction [GO:0009968] GO:0001650; GO:0001965; GO:0005634; GO:0005737; GO:0005829; GO:0009968; GO:0015629 17432 XM_044324123.1 0 0 3 3 11 NA NA NA NA NA NA 17433 XM_029340952.2 154 46 193 43 916 Q5XI32 1.69e-164 F-actin-capping protein subunit beta (CapZ beta) Rattus norvegicus (Rat) actin polymerization or depolymerization [GO:0008154]; barbed-end actin filament capping [GO:0051016]; cell morphogenesis [GO:0000902]; cell projection organization [GO:0030030]; cytoskeleton organization [GO:0007010]; lamellipodium assembly [GO:0030032]; muscle cell development [GO:0055001]; negative regulation of filopodium assembly [GO:0051490]; regulation of cell morphogenesis [GO:0022604]; regulation of lamellipodium assembly [GO:0010591] GO:0000902; GO:0003779; GO:0005903; GO:0007010; GO:0008154; GO:0008290; GO:0010591; GO:0014069; GO:0016020; GO:0022604; GO:0030017; GO:0030027; GO:0030030; GO:0030032; GO:0030863; GO:0032279; GO:0043025; GO:0043197; GO:0051015; GO:0051016; GO:0051490; GO:0055001; GO:0071203; GO:0097224; GO:0098685; GO:0098686 17434 XR_003827595.2 93 17 14 63 88 NA NA NA NA NA NA 17435 XM_029346755.2 1098 1446 1332 1461 435 NA NA NA NA NA NA 17436 XM_044321668.1 31 0 9 53 6 Q8K3Z0 5.81e-29 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 17437 XM_029325886.2 804 1114 11 1440 675 NA NA NA NA NA NA 17438 XM_029333043.2 0 8 0 0 0 Q8NE22 4.18e-43 SET domain-containing protein 9 (EC 2.1.1.-) Homo sapiens (Human) methylation [GO:0032259]; regulation of signal transduction by p53 class mediator [GO:1901796] GO:0005654; GO:0016278; GO:0032259; GO:1901796 17439 XM_044307541.1 6 0 0 8 6 NA NA NA NA NA NA 17440 XM_044310674.1 8 2 6 9 27 NA NA NA NA NA NA 17441 XR_006396003.1 913 946 553 851 737 Q7LL04 1.19e-27 UPF0676 protein C1494.01 Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) NA GO:0005634; GO:0005829 17442 XR_006396003.1 913 946 553 851 737 Q7LL04 1.19e-27 UPF0676 protein C1494.01 Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) NA GO:0005634; GO:0005829 17443 XM_029339853.2 44624 88697 75862 21639 51325 P36241 1.35e-76 60S ribosomal protein L19 Drosophila melanogaster (Fruit fly) cytoplasmic translation [GO:0002181] GO:0002181; GO:0003723; GO:0003735; GO:0022625; GO:0022626 17444 XR_006394565.1 241 183 282 410 296 NA NA NA NA NA NA 17445 XM_029344823.2 3776 1770 2247 2072 2164 Q9CZQ9 0 Bardet-Biedl syndrome 5 protein homolog Mus musculus (Mouse) cilium assembly [GO:0060271]; intracellular transport [GO:0046907]; protein transport [GO:0015031] GO:0005929; GO:0005930; GO:0015031; GO:0032266; GO:0034451; GO:0034464; GO:0036064; GO:0046907; GO:0060170; GO:0060271; GO:0061629 17446 XM_029324593.2 667 538 327 469 430 Q9V0D5 3.9e-70 Malate dehydrogenase (EC 1.1.1.37) Pyrococcus abyssi (strain GE5 / Orsay) tricarboxylic acid cycle [GO:0006099] GO:0005737; GO:0006099; GO:0030060 17447 XR_006391845.1 0 0 26 0 0 NA NA NA NA NA NA 17448 XM_029346024.2 626 396 309 518 615 Q80Z96 1.4e-127 Vang-like protein 1 (Loop-tail protein 2) (Van Gogh-like protein 1) Mus musculus (Mouse) pigmentation [GO:0043473] GO:0005886; GO:0016020; GO:0016328; GO:0043473 17449 XM_044326647.1 0 41 0 82 0 Q91ZV7 8.13e-54 Plexin domain-containing protein 1 (Tumor endothelial marker 7) Mus musculus (Mouse) spinal cord development [GO:0021510] GO:0005737; GO:0005886; GO:0005923; GO:0021510; GO:0030425; GO:0043025; GO:0043235 17450 XM_029334428.2 719 523 681 918 965 NA NA NA NA NA NA 17451 XR_006392903.1 41 2 25 5 151 NA NA NA NA NA NA 17452 XR_006393090.1 7 3 4 0 76 NA NA NA NA NA NA 17453 XM_029336859.2 3529 4603 2564 2422 1211 B5X5D0 3.6e-25 Piercer of microtubule wall 1 protein (Pierce1) (UPF0691 protein C9orf116 homolog) Salmo salar (Atlantic salmon) axoneme assembly [GO:0035082]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; establishment of left/right asymmetry [GO:0061966] GO:0003341; GO:0005634; GO:0005737; GO:0005879; GO:0007368; GO:0035082; GO:0061966 17454 XM_029333782.2 0 0 0 46 0 Q7TN88 3.3e-68 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 17455 XM_029333782.2 0 0 0 46 0 Q7TN88 3.22e-49 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 17456 XM_044313118.1 53 59 19 60 60 Q6H601 3.99e-23 DEAD-box ATP-dependent RNA helicase 22 (EC 3.6.4.13) Oryza sativa subsp. japonica (Rice) NA GO:0003723; GO:0003724; GO:0005524; GO:0016887 17457 XM_044326937.1 117 34 75 14 305 NA NA NA NA NA NA 17458 XM_044327328.1 38 22 37 95 125 Q8BIK4 2.8e-63 Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin-1) (Zizimin-1) Mus musculus (Mouse) positive regulation of GTPase activity [GO:0043547]; small GTPase mediated signal transduction [GO:0007264] GO:0005085; GO:0007264; GO:0012505; GO:0016020; GO:0031267; GO:0043547 17459 XM_029346897.2 0 92 79 507 51 A8KBE0 1.29e-86 Oxidation resistance protein 1 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005739 17460 XM_044307694.1 210 383 244 387 380 Q6DC77 1.27e-50 Membrane progestin receptor gamma-B (mPR gamma-B) (Progestin and adipoQ receptor family member V-B) Danio rerio (Zebrafish) (Brachydanio rerio) oogenesis [GO:0048477] GO:0005496; GO:0016020; GO:0038023; GO:0048477 17461 XM_044307658.1 7 2 2 8 7 NA NA NA NA NA NA 17462 XM_029354140.2 3907 3661 1244 3104 2385 A7RX69 5.09e-136 Metalloprotease TIKI homolog (EC 3.4.-.-) Nematostella vectensis (Starlet sea anemone) negative regulation of Wnt signaling pathway [GO:0030178]; proteolysis [GO:0006508] GO:0004222; GO:0006508; GO:0016020; GO:0030178; GO:0046872 17463 XR_006391910.1 2 0 1 0 15 NA NA NA NA NA NA 17464 XM_044313797.1 0 0 51 0 0 Q7RTR2 1.12e-72 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 17465 XM_044313797.1 0 0 51 0 0 Q7RTR2 1.75e-66 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 17466 XM_044313797.1 0 0 51 0 0 Q7RTR2 8.19e-66 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 17467 XM_044313797.1 0 0 51 0 0 Q7RTR2 5.3e-63 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 17468 XM_044313797.1 0 0 51 0 0 Q7RTR2 5.58e-55 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 17469 XM_029351325.2 19 69 58 0 217 Q6P0I8 3.56e-58 Exosome complex component MTR3 (Exosome component 6) (mRNA transport regulator 3 homolog) Danio rerio (Zebrafish) (Brachydanio rerio) nuclear mRNA surveillance [GO:0071028]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; U4 snRNA 3'-end processing [GO:0034475] GO:0000176; GO:0000177; GO:0000178; GO:0003723; GO:0005730; GO:0006364; GO:0016075; GO:0034427; GO:0034475; GO:0071028; GO:0071051 17470 XM_044317509.1 0 13 0 0 5 Q16515 2.56e-43 Acid-sensing ion channel 2 (ASIC2) (Amiloride-sensitive brain sodium channel) (Amiloride-sensitive cation channel 1, neuronal) (Amiloride-sensitive cation channel neuronal 1) (Brain sodium channel 1) (BNC1) (BNaC1) (Mammalian degenerin homolog) (MDEG) Homo sapiens (Human) central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; establishment of localization in cell [GO:0051649]; inorganic cation transmembrane transport [GO:0098662]; negative regulation of apoptotic process [GO:0043066]; peripheral nervous system development [GO:0007422]; phototransduction [GO:0007602]; positive regulation of synapse assembly [GO:0051965]; protein localization to synapse [GO:0035418]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback [GO:0003026]; regulation of vasoconstriction [GO:0019229]; response to acidic pH [GO:0010447]; sensory perception of sound [GO:0007605]; sensory perception of sour taste [GO:0050915]; sodium ion transmembrane transport [GO:0035725]; synapse assembly [GO:0007416] GO:0003026; GO:0005886; GO:0007268; GO:0007416; GO:0007417; GO:0007422; GO:0007602; GO:0007605; GO:0010447; GO:0015280; GO:0019229; GO:0022839; GO:0034765; GO:0035418; GO:0035725; GO:0042391; GO:0043025; GO:0043066; GO:0043197; GO:0050915; GO:0050974; GO:0051649; GO:0051965; GO:0098662 17471 XM_029355776.2 279 367 270 175 266 Q8CJ69 2.53e-94 BMP-binding endothelial regulator protein (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2) Mus musculus (Mouse) blood vessel development [GO:0001568]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; BMP signaling pathway [GO:0030509]; common-partner SMAD protein phosphorylation [GO:0007182]; endothelial cell activation [GO:0042118]; inner ear development [GO:0048839]; negative regulation of BMP signaling pathway [GO:0030514]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of sprouting angiogenesis [GO:1903672]; regulation of angiogenesis [GO:0045765]; regulation of endothelial cell migration [GO:0010594]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization [GO:0032880]; ureteric bud development [GO:0001657] GO:0001568; GO:0001657; GO:0002043; GO:0005576; GO:0005615; GO:0007182; GO:0010594; GO:0030509; GO:0030514; GO:0031012; GO:0032880; GO:0042118; GO:0045765; GO:0048839; GO:0060393; GO:0062023; GO:0070374; GO:1903672 17472 XM_029348430.2 109 93 43 82 93 NA NA NA NA NA NA 17473 XM_044313771.1 71 26 12 14 7 Q567B1 4.47e-79 Ubiquitin thioesterase OTU1 (EC 3.4.19.12) Danio rerio (Zebrafish) (Brachydanio rerio) endoplasmic reticulum unfolded protein response [GO:0030968]; macroautophagy [GO:0016236]; protein deubiquitination [GO:0016579]; protein K11-linked deubiquitination [GO:0035871]; protein K27-linked deubiquitination [GO:1990167]; protein K29-linked deubiquitination [GO:0035523]; protein K33-linked deubiquitination [GO:1990168]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0004843; GO:0005737; GO:0016236; GO:0016579; GO:0030433; GO:0030968; GO:0035523; GO:0035871; GO:0046872; GO:0070536; GO:0071108; GO:1990167; GO:1990168 17474 XM_044316043.1 19 25 19 25 56 NA NA NA NA NA NA 17475 XM_029332875.2 1851 1652 1227 1856 1449 Q62985 3.59e-45 SH2B adapter protein 1 (FceRI gamma-chain-interacting protein SH2-B) (SH2 domain-containing protein 1B) (SH2-B PH domain-containing signaling mediator 1) Rattus norvegicus (Rat) intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of SMAD protein signal transduction [GO:0060391]; regulation of DNA biosynthetic process [GO:2000278] GO:0005068; GO:0005634; GO:0005737; GO:0005886; GO:0030032; GO:0035556; GO:0045840; GO:0060391; GO:2000278 17476 XM_029358528.2 1207 1025 699 913 791 Q8N264 6.2e-109 Rho GTPase-activating protein 24 (Filamin-A-associated RhoGAP) (FilGAP) (RAC1- and CDC42-specific GTPase-activating protein of 72 kDa) (RC-GAP72) (Rho-type GTPase-activating protein 24) (RhoGAP of 73 kDa) (Sarcoma antigen NY-SAR-88) (p73RhoGAP) Homo sapiens (Human) activation of GTPase activity [GO:0090630]; angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; negative regulation of Rac protein signal transduction [GO:0035021]; negative regulation of ruffle assembly [GO:1900028]; signal transduction [GO:0007165]; wound healing, spreading of epidermal cells [GO:0035313] GO:0001525; GO:0005096; GO:0005737; GO:0005856; GO:0005912; GO:0005925; GO:0007165; GO:0030154; GO:0035021; GO:0035313; GO:0042995; GO:0090630; GO:1900028 17477 XM_029332040.2 1615 1642 1130 2131 1209 NA NA NA NA NA NA 17478 XM_044312846.1 9 6 22 237 0 NA NA NA NA NA NA 17479 XR_003822949.2 27 49 37 27 13 NA NA NA NA NA NA 17480 XR_006397117.1 15 0 15 2 27 NA NA NA NA NA NA 17481 XM_044315699.1 0 0 37 10 16 NA NA NA NA NA NA 17482 XM_044324684.1 217 51 78 383 376 Q8C0W1 1.55e-61 Ankyrin repeat and MYND domain-containing protein 1 Mus musculus (Mouse) NA GO:0046872 17483 XR_003828548.2 305 234 252 186 152 NA NA NA NA NA NA 17484 XM_029327721.2 91 34 38 87 51 NA NA NA NA NA NA 17485 XM_044321368.1 488 300 306 451 620 NA NA NA NA NA NA 17486 XM_029340997.2 54 8 0 23 0 Q8K078 3.9e-117 Solute carrier organic anion transporter family member 4A1 (Organic anion-transporting polypeptide E) (OATP-E) (Sodium-independent organic anion transporter E) (Solute carrier family 21 member 12) Mus musculus (Mouse) sodium-independent organic anion transport [GO:0043252]; thyroid hormone metabolic process [GO:0042403] GO:0005886; GO:0008514; GO:0015132; GO:0015347; GO:0015349; GO:0042403; GO:0043252 17487 XM_029336922.2 13 4 14 8 21 NA NA NA NA NA NA 17488 XR_006393239.1 60 181 186 167 64 NA NA NA NA NA NA 17489 XM_044323309.1 131 139 87 90 170 P16157 1.97e-57 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 17490 XM_044323309.1 131 139 87 90 170 P16157 1.36e-51 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 17491 XM_044323309.1 131 139 87 90 170 P16157 1.47e-45 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 17492 XM_044323309.1 131 139 87 90 170 P16157 8.01e-31 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 17493 XM_044323309.1 131 139 87 90 170 P16157 9.99e-26 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 17494 XR_003824280.2 79 61 38 140 272 NA NA NA NA NA NA 17495 XM_044320011.1 681 462 376 949 485 P54886 0 Delta-1-pyrroline-5-carboxylate synthase (P5CS) (Aldehyde dehydrogenase family 18 member A1) [Includes: Glutamate 5-kinase (GK) (EC 2.7.2.11) (Gamma-glutamyl kinase); Gamma-glutamyl phosphate reductase (GPR) (EC 1.2.1.41) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase)] Homo sapiens (Human) citrulline biosynthetic process [GO:0019240]; glutamate metabolic process [GO:0006536]; L-proline biosynthetic process [GO:0055129]; ornithine biosynthetic process [GO:0006592]; phosphorylation [GO:0016310]; proline biosynthetic process [GO:0006561] GO:0003723; GO:0004349; GO:0004350; GO:0005524; GO:0005739; GO:0005743; GO:0006536; GO:0006561; GO:0006592; GO:0016310; GO:0019240; GO:0042802; GO:0055129 17496 XM_044329244.1 0 0 0 0 45 P50748 0 Kinetochore-associated protein 1 (Rough deal homolog) (HsROD) (Rod) (hRod) Homo sapiens (Human) cell division [GO:0051301]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint signaling [GO:0007094]; protein localization to kinetochore involved in kinetochore assembly [GO:1903394]; protein-containing complex assembly [GO:0065003]; regulation of exit from mitosis [GO:0007096] GO:0000070; GO:0000922; GO:0005634; GO:0005737; GO:0005828; GO:0005829; GO:0005886; GO:0007094; GO:0007096; GO:0015629; GO:0031267; GO:0051301; GO:0065003; GO:1903394; GO:1990423 17497 XM_044318532.1 0 28 13 83 24 A0A974CYQ5 2.04e-107 NA NA NA NA 17498 XM_029340609.2 13 7 11 18 34 NA NA NA NA NA NA 17499 XM_029332788.2 17 10 33 33 50 Q16820 3.45e-44 Meprin A subunit beta (EC 3.4.24.63) (Endopeptidase-2) (Meprin B) (N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta) (PABA peptide hydrolase) (PPH beta) Homo sapiens (Human) inflammatory response [GO:0006954]; proteolysis [GO:0006508]; toxin transport [GO:1901998] GO:0004222; GO:0005576; GO:0005886; GO:0006508; GO:0006954; GO:0008270; GO:0017090; GO:0042802; GO:1901998 17500 XM_029338128.2 962 0 0 0 238 P08510 7.69e-88 Potassium voltage-gated channel protein Shaker (Protein minisleep) Drosophila melanogaster (Fruit fly) action potential [GO:0001508]; axon extension [GO:0048675]; behavioral response to ether [GO:0048150]; cellular response to dopamine [GO:1903351]; courtship behavior [GO:0007619]; detection of visible light [GO:0009584]; larval locomotory behavior [GO:0008345]; learning or memory [GO:0007611]; mating behavior, sex discrimination [GO:0048047]; positive regulation of circadian sleep/wake cycle, sleep [GO:0045938]; positive regulation of membrane potential [GO:0045838]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; proboscis extension reflex [GO:0007637]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; regulation of ion transmembrane transport [GO:0034765]; regulation of synaptic activity [GO:0060025]; sensory perception of taste [GO:0050909]; sleep [GO:0030431] GO:0001508; GO:0005249; GO:0005251; GO:0006813; GO:0007611; GO:0007619; GO:0007637; GO:0008076; GO:0008345; GO:0009584; GO:0016020; GO:0022843; GO:0030431; GO:0034765; GO:0045187; GO:0045838; GO:0045938; GO:0048047; GO:0048150; GO:0048675; GO:0050909; GO:0051260; GO:0060025; GO:0071805; GO:1903351 17501 XM_029357057.2 18 0 15 2 67 NA NA NA NA NA NA 17502 XM_029336733.2 20 110 79 87 152 NA NA NA NA NA NA 17503 XM_044318659.1 0 0 0 31 0 O75899 9.99e-72 Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51) (HG20) Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway [GO:0007186]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; neuron-glial cell signaling [GO:0150099]; synaptic transmission, GABAergic [GO:0051932] GO:0004888; GO:0004965; GO:0005737; GO:0005886; GO:0007186; GO:0007193; GO:0007194; GO:0007214; GO:0007268; GO:0038039; GO:0043005; GO:0045211; GO:0046982; GO:0051932; GO:0150099; GO:1902710; GO:1902712 17504 XM_044323052.1 97 170 230 342 42 Q08DY9 2.58e-40 Caspase-3 (CASP-3) (EC 3.4.22.56) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12] Bos taurus (Bovine) positive regulation of amyloid-beta formation [GO:1902004]; proteolysis [GO:0006508]; regulation of protein stability [GO:0031647] GO:0004175; GO:0005737; GO:0006508; GO:0031647; GO:0097153; GO:0097199; GO:0097200; GO:1902004 17505 XM_029332893.2 1021 663 542 650 778 Q9W704 5.27e-39 RPA-interacting protein A (RPA-interacting protein alpha) (XRIPalpha) Xenopus laevis (African clawed frog) NA GO:0005634; GO:0046872 17506 XM_029351963.2 28407 25103 17680 25519 16538 P29773 1.31e-36 Protein C-ets-2 Lytechinus variegatus (Green sea urchin) (Echinus variegatus) regulation of transcription by RNA polymerase II [GO:0006357] GO:0003700; GO:0005634; GO:0006357; GO:0043565 17507 XM_044307030.1 0 0 1 3 12 NA NA NA NA NA NA 17508 XM_044317492.1 25 30 31 11 33 NA NA NA NA NA NA 17509 XM_044328653.1 155 83 324 345 131 Q92820 1.43e-89 Gamma-glutamyl hydrolase (EC 3.4.19.9) (Conjugase) (GH) (Gamma-Glu-X carboxypeptidase) Homo sapiens (Human) tetrahydrofolylpolyglutamate metabolic process [GO:0046900] GO:0005576; GO:0005615; GO:0005634; GO:0005773; GO:0008238; GO:0008242; GO:0034722; GO:0035578; GO:0035580; GO:0042470; GO:0046900; GO:0070062; GO:1904724 17510 XM_029332664.2 1168 599 525 1087 1364 O93309 0 Structural maintenance of chromosomes protein 3 (SMC protein 3) (SMC-3) Xenopus laevis (African clawed frog) cell division [GO:0051301]; chromosome organization [GO:0051276]; DNA repair [GO:0006281]; meiotic cell cycle [GO:0051321]; regulation of DNA replication [GO:0006275] GO:0000775; GO:0000785; GO:0005524; GO:0005634; GO:0006275; GO:0006281; GO:0016887; GO:0030893; GO:0051276; GO:0051301; GO:0051321 17511 XM_029328617.2 15 11 10 26 25 NA NA NA NA NA NA 17512 XM_044312594.1 0 0 10 0 1 NA NA NA NA NA NA 17513 XM_044326460.1 712 647 355 758 458 Q28FE4 5.61e-94 MORN repeat-containing protein 5 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA NA 17514 XM_029340976.2 77 68 114 87 160 NA NA NA NA NA NA 17515 XM_044324557.1 0 0 0 50 0 H1AFJ5 3.02e-39 Amiloride-sensitive sodium channel subunit alpha (Alpha-NaCH) (Epithelial Na(+) channel subunit alpha) (Alpha-ENaC) (Nonvoltage-gated sodium channel 1 subunit alpha) (SCNEA) Neoceratodus forsteri (Australian lungfish) (Ceratodus forsteri) sodium ion transmembrane transport [GO:0035725] GO:0001669; GO:0005737; GO:0015280; GO:0016324; GO:0031514; GO:0034706; GO:0035725 17516 XM_029328865.2 420 408 280 123 325 Q8NI36 0 WD repeat-containing protein 36 (T-cell activation WD repeat-containing protein) (TA-WDRP) Homo sapiens (Human) response to stimulus [GO:0050896]; rRNA processing [GO:0006364]; visual perception [GO:0007601] GO:0003723; GO:0005654; GO:0005730; GO:0006364; GO:0007601; GO:0032040; GO:0034388; GO:0050896 17517 XM_029350455.2 461 182 39 385 289 Q5R7J8 3.44e-70 Protein tyrosine phosphatase type IVA 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cell cycle [GO:0007049]; protein dephosphorylation [GO:0006470] GO:0004725; GO:0005634; GO:0005769; GO:0005783; GO:0005819; GO:0005886; GO:0006470; GO:0007049; GO:0008138 17518 XR_006395654.1 68 3 32 19 202 NA NA NA NA NA NA 17519 XM_029334519.2 3905 3286 1858 3275 2668 Q6NVP8 1.74e-179 Alpha-(1,6)-fucosyltransferase (Alpha1-6FucT) (EC 2.4.1.68) (GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase) (GDP-fucose--glycoprotein fucosyltransferase) (Glycoprotein 6-alpha-L-fucosyltransferase) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) GDP-L-fucose metabolic process [GO:0046368]; protein N-linked glycosylation via asparagine [GO:0018279] GO:0008424; GO:0017124; GO:0018279; GO:0032580; GO:0046368 17520 XM_044309430.1 15 0 6 4 1 NA NA NA NA NA NA 17521 XM_044306740.1 789 427 633 1672 1765 NA NA NA NA NA NA 17522 XM_044307513.1 6 179 182 338 272 Q61382 1.69e-22 TNF receptor-associated factor 4 (EC 2.3.2.27) (Cysteine-rich motif associated to RING and Traf domains protein 1) Mus musculus (Mouse) activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; innate immune response [GO:0045087]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein kinase activity [GO:0045860]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; respiratory gaseous exchange by respiratory system [GO:0007585]; respiratory tube development [GO:0030323] GO:0001650; GO:0005164; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0005923; GO:0006915; GO:0007250; GO:0007585; GO:0008270; GO:0016740; GO:0019901; GO:0030323; GO:0031625; GO:0031996; GO:0042802; GO:0042981; GO:0043122; GO:0043161; GO:0045087; GO:0045860; GO:0046330; GO:0048471; GO:0050699 17523 XM_044320782.1 3 14 3 1 6 Q80XJ3 3.15e-71 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 17524 XM_044320782.1 3 14 3 1 6 Q80XJ3 4.15e-69 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 17525 XM_044320782.1 3 14 3 1 6 Q80XJ3 1.15e-68 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 17526 XM_044320782.1 3 14 3 1 6 Q80XJ3 1.53e-68 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 17527 XM_044320782.1 3 14 3 1 6 Q80XJ3 6.29e-67 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 17528 XM_044320782.1 3 14 3 1 6 Q80XJ3 2.52e-60 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 17529 XM_044320782.1 3 14 3 1 6 Q80XJ3 5.23e-60 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 17530 XM_044320782.1 3 14 3 1 6 Q80XJ3 1.1e-58 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 17531 XM_044320782.1 3 14 3 1 6 Q80XJ3 3.69e-50 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 17532 XM_044320782.1 3 14 3 1 6 Q80XJ3 2.63e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 17533 XM_044308135.1 410 0 339 481 399 Q4GZT4 0 Broad substrate specificity ATP-binding cassette transporter ABCG2 (EC 7.6.2.2) (ATP-binding cassette sub-family G member 2) (Urate exporter) (CD antigen CD338) Bos taurus (Bovine) biotin transport [GO:0015878]; lipid transport [GO:0006869]; renal urate salt excretion [GO:0097744]; riboflavin transport [GO:0032218]; transmembrane transport [GO:0055085] GO:0005524; GO:0005886; GO:0006869; GO:0008559; GO:0015143; GO:0015225; GO:0015562; GO:0015878; GO:0016020; GO:0016324; GO:0031526; GO:0031966; GO:0032217; GO:0032218; GO:0042626; GO:0045121; GO:0055085; GO:0097744 17534 XM_029342678.2 0 24 6 0 0 Q8TDX7 3.26e-176 Serine/threonine-protein kinase Nek7 (EC 2.7.11.1) (Never in mitosis A-related kinase 7) (NimA-related protein kinase 7) Homo sapiens (Human) cellular response to potassium ion [GO:0035865]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of NLRP3 inflammasome complex assembly [GO:1900227]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein phosphorylation [GO:0006468]; regulation of mitotic cell cycle [GO:0007346]; spindle assembly [GO:0051225] GO:0000922; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005815; GO:0005874; GO:0006468; GO:0007346; GO:0018105; GO:0032212; GO:0035865; GO:0046872; GO:0051225; GO:0051973; GO:0106310; GO:0140677; GO:1900227; GO:1904355 17535 XR_006391301.1 85 43 102 136 108 NA NA NA NA NA NA 17536 XM_044321373.1 0 3 16 39 20 NA NA NA NA NA NA 17537 XM_029328268.2 0 0 15 33 16 Q5ZJP7 4.58e-28 BTB/POZ domain-containing protein KCTD7 Gallus gallus (Chicken) membrane hyperpolarization [GO:0060081]; positive regulation of transporter activity [GO:0032411]; protein homooligomerization [GO:0051260] GO:0005829; GO:0005886; GO:0032411; GO:0051260; GO:0060081 17538 XR_006394695.1 12 7 0 24 1 NA NA NA NA NA NA 17539 XM_029328785.2 547 359 326 606 394 NA NA NA NA NA NA 17540 XM_044323978.1 8 55 74 132 86 NA NA NA NA NA NA 17541 XM_044323222.1 613 294 264 419 648 Q6AY70 2.76e-50 KAT8 regulatory NSL complex subunit 2 (NSL complex protein NSL2) (Non-specific lethal 2 homolog) Rattus norvegicus (Rat) chromatin organization [GO:0006325]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; positive regulation of histone H3-K4 methylation [GO:0051571]; regulation of dosage compensation by inactivation of X chromosome [GO:1900095] GO:0000123; GO:0005634; GO:0006325; GO:0043981; GO:0043982; GO:0043984; GO:0044545; GO:0051571; GO:1900095 17542 XM_029339343.2 374 230 253 267 411 Q07DZ7 5.37e-52 Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein) Ornithorhynchus anatinus (Duckbill platypus) cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; male meiotic nuclear division [GO:0007140]; piRNA processing [GO:0034587]; spermatogenesis [GO:0007283] GO:0007140; GO:0007283; GO:0030154; GO:0034587; GO:0043046; GO:0071546 17543 XM_044322739.1 4 1116 6 11 1195 NA NA NA NA NA NA 17544 XM_029346385.2 386 540 170 245 128 A0JN95 9.79e-75 12S rRNA N4-methylcytidine methyltransferase (12S rRNA m4C methyltransferase) (EC 2.1.1.-) (Methyltransferase 5 domain-containing protein 1) (Methyltransferase-like protein 15) Bos taurus (Bovine) rRNA base methylation [GO:0070475] GO:0005759; GO:0070475; GO:0071424 17545 XM_044326844.1 359 160 246 323 138 NA NA NA NA NA NA 17546 XM_044308888.1 0 0 0 6 1 NA NA NA NA NA NA 17547 XR_006395902.1 0 0 3 0 422 NA NA NA NA NA NA 17548 XM_044320602.1 89 0 26 0 172 Q9Z2V5 8.66e-114 Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Histone deacetylase mHDA2) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-) Mus musculus (Mouse) aggresome assembly [GO:0070842]; axonal transport of mitochondrion [GO:0019896]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to misfolded protein [GO:0071218]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to topologically incorrect protein [GO:0035967]; cilium disassembly [GO:0061523]; collateral sprouting [GO:0048668]; dendritic spine morphogenesis [GO:0060997]; epigenetic regulation of gene expression [GO:0040029]; histone deacetylation [GO:0016575]; Hsp90 deacetylation [GO:0070846]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; mitochondrion localization [GO:0051646]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of protein-containing complex disassembly [GO:0043242]; negative regulation of proteolysis [GO:0045861]; negative regulation of transcription by RNA polymerase II [GO:0000122]; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:0061734]; peptidyl-lysine deacetylation [GO:0034983]; polyubiquitinated misfolded protein transport [GO:0070845]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of hydrogen peroxide-mediated programmed cell death [GO:1901300]; positive regulation of mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of tubulin deacetylation [GO:0090044]; protein deacetylation [GO:0006476]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; protein-containing complex disassembly [GO:0032984]; regulation of establishment of protein localization [GO:0070201]; regulation of fat cell differentiation [GO:0045598]; regulation of macroautophagy [GO:0016241]; regulation of mitochondrion organization [GO:0010821]; regulation of protein stability [GO:0031647]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]; response to dexamethasone [GO:0071548]; response to growth factor [GO:0070848]; response to immobilization stress [GO:0035902]; response to misfolded protein [GO:0051788]; tubulin deacetylation [GO:0090042]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] GO:0000118; GO:0000122; GO:0000209; GO:0000978; GO:0001222; GO:0001975; GO:0003779; GO:0004407; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0005829; GO:0005874; GO:0005875; GO:0005901; GO:0006476; GO:0006511; GO:0006515; GO:0006886; GO:0007026; GO:0008013; GO:0008017; GO:0008270; GO:0010634; GO:0010821; GO:0015630; GO:0016234; GO:0016235; GO:0016241; GO:0016575; GO:0019896; GO:0030424; GO:0030425; GO:0031252; GO:0031333; GO:0031593; GO:0031625; GO:0031647; GO:0031648; GO:0032418; GO:0032984; GO:0032991; GO:0033138; GO:0033558; GO:0034983; GO:0035902; GO:0035967; GO:0036064; GO:0040029; GO:0042826; GO:0042903; GO:0043005; GO:0043014; GO:0043025; GO:0043130; GO:0043162; GO:0043204; GO:0043242; GO:0045598; GO:0045861; GO:0048156; GO:0048471; GO:0048487; GO:0048668; GO:0048843; GO:0050775; GO:0051412; GO:0051646; GO:0051787; GO:0051788; GO:0051879; GO:0051968; GO:0060997; GO:0061523; GO:0061734; GO:0070201; GO:0070301; GO:0070840; GO:0070842; GO:0070845; GO:0070846; GO:0070848; GO:0071218; GO:0071374; GO:0071548; GO:0090042; GO:0090044; GO:0098779; GO:1901300; GO:1901984; GO:1903223; GO:1904056; GO:1904115; GO:2000273 17549 XM_044320602.1 89 0 26 0 172 Q9Z2V5 3.53e-104 Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Histone deacetylase mHDA2) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-) Mus musculus (Mouse) aggresome assembly [GO:0070842]; axonal transport of mitochondrion [GO:0019896]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to misfolded protein [GO:0071218]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to topologically incorrect protein [GO:0035967]; cilium disassembly [GO:0061523]; collateral sprouting [GO:0048668]; dendritic spine morphogenesis [GO:0060997]; epigenetic regulation of gene expression [GO:0040029]; histone deacetylation [GO:0016575]; Hsp90 deacetylation [GO:0070846]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; mitochondrion localization [GO:0051646]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of protein-containing complex disassembly [GO:0043242]; negative regulation of proteolysis [GO:0045861]; negative regulation of transcription by RNA polymerase II [GO:0000122]; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:0061734]; peptidyl-lysine deacetylation [GO:0034983]; polyubiquitinated misfolded protein transport [GO:0070845]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of hydrogen peroxide-mediated programmed cell death [GO:1901300]; positive regulation of mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of tubulin deacetylation [GO:0090044]; protein deacetylation [GO:0006476]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; protein-containing complex disassembly [GO:0032984]; regulation of establishment of protein localization [GO:0070201]; regulation of fat cell differentiation [GO:0045598]; regulation of macroautophagy [GO:0016241]; regulation of mitochondrion organization [GO:0010821]; regulation of protein stability [GO:0031647]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]; response to dexamethasone [GO:0071548]; response to growth factor [GO:0070848]; response to immobilization stress [GO:0035902]; response to misfolded protein [GO:0051788]; tubulin deacetylation [GO:0090042]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] GO:0000118; GO:0000122; GO:0000209; GO:0000978; GO:0001222; GO:0001975; GO:0003779; GO:0004407; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0005829; GO:0005874; GO:0005875; GO:0005901; GO:0006476; GO:0006511; GO:0006515; GO:0006886; GO:0007026; GO:0008013; GO:0008017; GO:0008270; GO:0010634; GO:0010821; GO:0015630; GO:0016234; GO:0016235; GO:0016241; GO:0016575; GO:0019896; GO:0030424; GO:0030425; GO:0031252; GO:0031333; GO:0031593; GO:0031625; GO:0031647; GO:0031648; GO:0032418; GO:0032984; GO:0032991; GO:0033138; GO:0033558; GO:0034983; GO:0035902; GO:0035967; GO:0036064; GO:0040029; GO:0042826; GO:0042903; GO:0043005; GO:0043014; GO:0043025; GO:0043130; GO:0043162; GO:0043204; GO:0043242; GO:0045598; GO:0045861; GO:0048156; GO:0048471; GO:0048487; GO:0048668; GO:0048843; GO:0050775; GO:0051412; GO:0051646; GO:0051787; GO:0051788; GO:0051879; GO:0051968; GO:0060997; GO:0061523; GO:0061734; GO:0070201; GO:0070301; GO:0070840; GO:0070842; GO:0070845; GO:0070846; GO:0070848; GO:0071218; GO:0071374; GO:0071548; GO:0090042; GO:0090044; GO:0098779; GO:1901300; GO:1901984; GO:1903223; GO:1904056; GO:1904115; GO:2000273 17550 XM_044316390.1 1028 1079 697 1243 1370 NA NA NA NA NA NA 17551 XM_029337545.2 564 108 671 639 343 Q9UIC8 1.23e-114 Leucine carboxyl methyltransferase 1 (EC 2.1.1.233) (Protein-leucine O-methyltransferase) ([Phosphatase 2A protein]-leucine-carboxy methyltransferase 1) Homo sapiens (Human) C-terminal protein methylation [GO:0006481]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of protein-containing complex assembly [GO:0031333]; protein methylation [GO:0006479]; protein modification process [GO:0036211]; regulation of apoptotic process [GO:0042981]; regulation of glucose metabolic process [GO:0010906]; regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090266] GO:0000086; GO:0003880; GO:0005654; GO:0005829; GO:0006479; GO:0006481; GO:0008757; GO:0010906; GO:0018423; GO:0031333; GO:0036211; GO:0042981; GO:0090266 17552 XM_044318002.1 4 23 2 0 2 NA NA NA NA NA NA 17553 XM_044313837.1 36 0 1 21 8 NA NA NA NA NA NA 17554 XM_044321493.1 17 59 5 202 186 Q01804 3.63e-71 OTU domain-containing protein 4 (EC 3.4.19.12) (HIV-1-induced protein HIN-1) Homo sapiens (Human) innate immune response [GO:0045087]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; positive regulation of DNA demethylation [GO:1901537]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; regulation of protein K48-linked deubiquitination [GO:1903093] GO:0003723; GO:0004843; GO:0005634; GO:0005829; GO:0016579; GO:0034122; GO:0045087; GO:0060090; GO:0061578; GO:0070536; GO:0071108; GO:1901537; GO:1903093; GO:2000660 17555 XM_029335993.2 785 501 613 567 457 NA NA NA NA NA NA 17556 XM_029333868.2 1926 1222 870 1211 1301 NA NA NA NA NA NA 17557 XR_003825652.2 810 283 280 1127 527 NA NA NA NA NA NA 17558 XM_044327438.1 2172 1379 1340 2057 1609 NA NA NA NA NA NA 17559 XM_044327752.1 137 83 153 197 402 Q05609 6.55e-27 Serine/threonine-protein kinase CTR1 (EC 2.7.11.1) (Protein CONSTITUTIVE TRIPLE RESPONSE1) Arabidopsis thaliana (Mouse-ear cress) ethylene-activated signaling pathway [GO:0009873]; gibberellin biosynthetic process [GO:0009686]; negative regulation of ethylene-activated signaling pathway [GO:0010105]; protein autophosphorylation [GO:0046777]; regulation of post-embryonic root development [GO:2000069]; regulation of stem cell division [GO:2000035]; regulation of timing of transition from vegetative to reproductive phase [GO:0048510]; response to ethylene [GO:0009723]; response to fructose [GO:0009750]; response to hypoxia [GO:0001666]; response to sucrose [GO:0009744]; sugar mediated signaling pathway [GO:0010182] GO:0001666; GO:0004674; GO:0004712; GO:0005524; GO:0005789; GO:0009686; GO:0009723; GO:0009744; GO:0009750; GO:0009873; GO:0010105; GO:0010182; GO:0046777; GO:0048510; GO:0106310; GO:2000035; GO:2000069 17560 XM_044328873.1 84 552 13 24 20 NA NA NA NA NA NA 17561 XM_029338426.2 47 444 56 87 0 P48727 0 Serine/threonine-protein phosphatase PP1-beta (EC 3.1.3.16) (CeGLC-7-beta) (Glc seven-like phosphatase 2) Caenorhabditis elegans cell division [GO:0051301]; chromatin organization [GO:0006325]; meiotic cell cycle [GO:0051321]; peptidyl-serine dephosphorylation [GO:0070262] GO:0004722; GO:0005634; GO:0005694; GO:0005737; GO:0006325; GO:0017018; GO:0031965; GO:0046872; GO:0051301; GO:0051321; GO:0070262 17562 XM_029334047.2 878 584 361 737 652 Q3B752 2.76e-67 Thymidylate kinase (EC 2.7.4.9) (dTMP kinase) Danio rerio (Zebrafish) (Brachydanio rerio) dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]; phosphorylation [GO:0016310] GO:0004550; GO:0004798; GO:0005524; GO:0005634; GO:0005737; GO:0005739; GO:0006227; GO:0006233; GO:0006235; GO:0009041; GO:0016310 17563 XM_029323663.2 2454 1878 1729 3488 915 Q2KIA4 2.8e-117 Stearoyl-CoA desaturase 5 (EC 1.14.19.1) (Acyl-CoA-desaturase 4) (Stearoyl-CoA 9-desaturase) Bos taurus (Bovine) monounsaturated fatty acid biosynthetic process [GO:1903966]; unsaturated fatty acid biosynthetic process [GO:0006636] GO:0004768; GO:0005506; GO:0005789; GO:0006636; GO:0016491; GO:1903966 17564 XM_029348707.2 2101 1332 873 1042 863 NA NA NA NA NA NA 17565 XR_006396324.1 705 1847 1547 576 1193 NA NA NA NA NA NA 17566 XR_006397195.1 36 10 29 8 30 NA NA NA NA NA NA 17567 XR_006394649.1 84 42 206 173 31 NA NA NA NA NA NA 17568 XR_006395438.1 1871 1387 894 1777 1550 Q5SQX6 0 Cytoplasmic FMR1-interacting protein 2 (p53-inducible protein 121) Mus musculus (Mouse) activation of cysteine-type endopeptidase activity [GO:0097202]; apoptotic process [GO:0006915]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; dendrite extension [GO:0097484]; neuron projection development [GO:0031175]; positive regulation of neurotrophin TRK receptor signaling pathway [GO:0051388]; positive regulation of proteolysis [GO:0045862]; regulation of actin filament polymerization [GO:0030833] GO:0000902; GO:0005634; GO:0005737; GO:0006915; GO:0030833; GO:0031175; GO:0031209; GO:0031267; GO:0043005; GO:0045202; GO:0045862; GO:0048471; GO:0051388; GO:0097202; GO:0097484; GO:0098609 17569 XR_006395438.1 1871 1387 894 1777 1550 Q5SQX6 7.62e-147 Cytoplasmic FMR1-interacting protein 2 (p53-inducible protein 121) Mus musculus (Mouse) activation of cysteine-type endopeptidase activity [GO:0097202]; apoptotic process [GO:0006915]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; dendrite extension [GO:0097484]; neuron projection development [GO:0031175]; positive regulation of neurotrophin TRK receptor signaling pathway [GO:0051388]; positive regulation of proteolysis [GO:0045862]; regulation of actin filament polymerization [GO:0030833] GO:0000902; GO:0005634; GO:0005737; GO:0006915; GO:0030833; GO:0031175; GO:0031209; GO:0031267; GO:0043005; GO:0045202; GO:0045862; GO:0048471; GO:0051388; GO:0097202; GO:0097484; GO:0098609 17570 XR_006392933.1 41 2 25 5 151 NA NA NA NA NA NA 17571 XM_044329022.1 924 287 508 1111 447 Q3UR85 5.42e-131 Myelin regulatory factor (EC 3.4.-.-) (Myelin gene regulatory factor) [Cleaved into: Myelin regulatory factor, N-terminal; Myelin regulatory factor, C-terminal] Mus musculus (Mouse) central nervous system myelin maintenance [GO:0032286]; central nervous system myelination [GO:0022010]; oligodendrocyte development [GO:0014003]; oligodendrocyte differentiation [GO:0048709]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of myelination [GO:0031643]; protein autoprocessing [GO:0016540]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000981; GO:0003677; GO:0003700; GO:0005634; GO:0005654; GO:0005737; GO:0005789; GO:0005794; GO:0005829; GO:0006357; GO:0008233; GO:0014003; GO:0016540; GO:0022010; GO:0031643; GO:0032286; GO:0042802; GO:0043565; GO:0045893; GO:0048709 17572 XM_029356239.2 672 799 494 599 1073 Q3ZBL9 2.24e-55 Cyclin-H Bos taurus (Bovine) cell cycle [GO:0007049]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366] GO:0000079; GO:0005634; GO:0005675; GO:0006357; GO:0006366; GO:0007049; GO:0016538; GO:0070816; GO:0070985 17573 XR_003823273.2 242 15 349 11 658 NA NA NA NA NA NA 17574 XR_003825657.2 195 210 142 209 266 NA NA NA NA NA NA 17575 XM_029356292.2 0 0 0 139 347 O16025 8.55e-35 Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (AOS) (EC 4.2.1.-) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)] Plexaura homomalla (Black sea rod) arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; lipid oxidation [GO:0034440]; oxylipin biosynthetic process [GO:0031408] GO:0005506; GO:0005737; GO:0006633; GO:0009978; GO:0016020; GO:0019369; GO:0020037; GO:0031408; GO:0034440; GO:0047677 17576 XM_029324305.2 1848 1629 1163 2188 1430 Q32NR4 8.2e-93 Tetratricopeptide repeat protein 29 (TPR repeat protein 29) Xenopus laevis (African clawed frog) cilium movement [GO:0003341] GO:0003341; GO:0005737; GO:0005856; GO:0036126 17577 XM_029334138.2 1784 1567 852 2216 2445 Q29RP8 1.26e-106 Histone-lysine N-methyltransferase KMT5B (Lysine-specific methyltransferase 5B) (Suppressor of variegation 4-20 homolog 1) (Su(var)4-20 homolog 1) (Suv4-20h1) ([histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B) (EC 2.1.1.362) ([histone H4]-lysine20 N-methyltransferase KMT5B) (EC 2.1.1.361) Bos taurus (Bovine) chromatin organization [GO:0006325]; DNA repair [GO:0006281]; histone H4-K20 dimethylation [GO:0034772]; histone H4-K20 trimethylation [GO:0034773]; muscle organ development [GO:0007517]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; positive regulation of isotype switching [GO:0045830] GO:0003682; GO:0005634; GO:0005694; GO:0006281; GO:0006325; GO:0007517; GO:0018024; GO:0034772; GO:0034773; GO:0042799; GO:0045830; GO:0046872; GO:0140941; GO:0140944; GO:1904047; GO:2001034 17578 XM_044313070.1 981 0 408 386 222 Q5U2V4 3.5e-173 Phospholipase B-like 1 (EC 3.1.1.-) (LAMA-like protein 1) (Lamina ancestor homolog 1) (Phospholipase B domain-containing protein 1) [Cleaved into: Phospholipase B-like 1 chain A; Phospholipase B-like 1 chain B; Phospholipase B-like 1 chain C] Rattus norvegicus (Rat) phospholipid catabolic process [GO:0009395] GO:0004620; GO:0005576; GO:0005615; GO:0005764; GO:0009395 17579 XM_044309992.1 10 3 0 4 47 NA NA NA NA NA NA 17580 XM_029341930.2 39 0 22 0 10 P97677 7.55e-84 Delta-like protein 1 (Drosophila Delta homolog 1) (Delta1) Rattus norvegicus (Rat) astrocyte development [GO:0014002]; auditory receptor cell fate commitment [GO:0009912]; cell fate determination [GO:0001709]; cell-cell signaling [GO:0007267]; cerebellar molecular layer formation [GO:0021688]; cerebellar Purkinje cell layer structural organization [GO:0021693]; clathrin-dependent endocytosis [GO:0072583]; compartment pattern specification [GO:0007386]; determination of left/right symmetry [GO:0007368]; endothelial tip cell fate specification [GO:0097102]; energy homeostasis [GO:0097009]; heart looping [GO:0001947]; inhibition of neuroepithelial cell differentiation [GO:0002085]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear development [GO:0048839]; lateral inhibition [GO:0046331]; left/right axis specification [GO:0070986]; loop of Henle development [GO:0072070]; marginal zone B cell differentiation [GO:0002315]; myeloid cell differentiation [GO:0030099]; negative regulation of cardiac muscle cell differentiation [GO:2000726]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal cell differentiation [GO:0045605]; negative regulation of epithelial cell differentiation [GO:0030857]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of inner ear auditory receptor cell differentiation [GO:0045608]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of Notch signaling pathway [GO:0045746]; nephron development [GO:0072006]; nervous system development [GO:0007399]; neuroepithelial cell differentiation [GO:0060563]; neuron differentiation [GO:0030182]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; Notch signaling pathway involved in arterial endothelial cell fate commitment [GO:0060853]; organ growth [GO:0035265]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endocytosis [GO:0045807]; positive regulation of gene expression [GO:0010628]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of skeletal muscle tissue growth [GO:0048633]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proximal tubule development [GO:0072014]; proximal/distal pattern formation [GO:0009954]; regulation of blood pressure [GO:0008217]; regulation of cell adhesion [GO:0030155]; regulation of cell division [GO:0051302]; regulation of growth [GO:0040008]; regulation of neurogenesis [GO:0050767]; regulation of skeletal muscle tissue growth [GO:0048631]; regulation of somitogenesis [GO:0014807]; regulation of vascular endothelial growth factor signaling pathway [GO:1900746]; retina development in camera-type eye [GO:0060041]; retina morphogenesis in camera-type eye [GO:0060042]; skeletal muscle tissue growth [GO:0048630]; skin epidermis development [GO:0098773]; somite specification [GO:0001757]; somitogenesis [GO:0001756]; spinal cord development [GO:0021510]; type B pancreatic cell development [GO:0003323] GO:0001709; GO:0001756; GO:0001757; GO:0001947; GO:0002085; GO:0002315; GO:0003323; GO:0005112; GO:0005509; GO:0005886; GO:0005912; GO:0007219; GO:0007267; GO:0007368; GO:0007386; GO:0007399; GO:0008217; GO:0008284; GO:0008285; GO:0009912; GO:0009954; GO:0010628; GO:0014002; GO:0014807; GO:0016324; GO:0021510; GO:0021688; GO:0021693; GO:0030099; GO:0030155; GO:0030182; GO:0030857; GO:0030957; GO:0031410; GO:0032693; GO:0034351; GO:0035265; GO:0040008; GO:0042491; GO:0045121; GO:0045596; GO:0045605; GO:0045608; GO:0045638; GO:0045662; GO:0045665; GO:0045746; GO:0045747; GO:0045807; GO:0045944; GO:0046331; GO:0048018; GO:0048630; GO:0048631; GO:0048633; GO:0048665; GO:0048839; GO:0050767; GO:0051302; GO:0060041; GO:0060042; GO:0060563; GO:0060853; GO:0070986; GO:0072006; GO:0072014; GO:0072070; GO:0072583; GO:0097009; GO:0097102; GO:0097110; GO:0097150; GO:0098773; GO:1900746; GO:1903672; GO:2000726 17581 XM_044327977.1 23 0 11 5 41 NA NA NA NA NA NA 17582 XM_044324753.1 622 284 183 478 482 P83436 0 Conserved oligomeric Golgi complex subunit 7 (COG complex subunit 7) (Component of oligomeric Golgi complex 7) Homo sapiens (Human) glycosylation [GO:0070085]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886]; protein glycosylation [GO:0006486]; protein localization to Golgi apparatus [GO:0034067]; protein localization to organelle [GO:0033365]; protein stabilization [GO:0050821]; retrograde transport, vesicle recycling within Golgi [GO:0000301]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] GO:0000139; GO:0000301; GO:0005730; GO:0005794; GO:0006486; GO:0006886; GO:0006890; GO:0007030; GO:0017119; GO:0032588; GO:0033365; GO:0034067; GO:0043231; GO:0050821; GO:0070085 17583 XM_029323447.2 59 109 184 72 137 Q8CHN8 1.79e-36 Mannan-binding lectin serine protease 1 (EC 3.4.21.-) (Complement factor MASP-3) (Complement-activating component of Ra-reactive factor) (Mannose-binding lectin-associated serine protease 1) (MASP-1) (Mannose-binding protein-associated serine protease) (Ra-reactive factor serine protease p100) (RaRF) (Serine protease 5) [Cleaved into: Mannan-binding lectin serine protease 1 heavy chain; Mannan-binding lectin serine protease 1 light chain] Rattus norvegicus (Rat) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; positive regulation of opsonization [GO:1903028]; proteolysis [GO:0006508] GO:0001867; GO:0002752; GO:0004252; GO:0005509; GO:0005615; GO:0006508; GO:0006956; GO:0008233; GO:0042803; GO:0048306; GO:1903028; GO:1905370 17584 XM_029335228.2 143 246 0 159 0 Q6GM82 2.57e-176 Alanine aminotransferase 2 (ALT2) (EC 2.6.1.2) (Glutamate pyruvate transaminase 2) (GPT 2) (Glutamic--alanine transaminase 2) (Glutamic--pyruvic transaminase 2) Xenopus laevis (African clawed frog) 2-oxoglutarate metabolic process [GO:0006103]; biosynthetic process [GO:0009058]; L-alanine catabolic process [GO:0042853]; L-alanine metabolic process [GO:0042851] GO:0004021; GO:0006103; GO:0009058; GO:0030170; GO:0042851; GO:0042853 17585 XM_044316205.1 14 24 49 38 33 NA NA NA NA NA NA 17586 XM_044319753.1 2864 2375 1332 1868 1693 A5D9C6 2.31e-74 Repressor of RNA polymerase III transcription MAF1 homolog Bos taurus (Bovine) negative regulation of transcription by RNA polymerase III [GO:0016480] GO:0000994; GO:0005634; GO:0005737; GO:0016480 17587 XM_044310586.1 6 0 0 1 1 NA NA NA NA NA NA 17588 XM_044322767.1 11689 7345 4938 10652 3339 Q3TZZ7 1.52e-120 Extended synaptotagmin-2 (E-Syt2) Mus musculus (Mouse) endocytosis [GO:0006897]; endoplasmic reticulum-plasma membrane tethering [GO:0061817]; lipid transport [GO:0006869] GO:0005509; GO:0005544; GO:0005789; GO:0005829; GO:0005886; GO:0006869; GO:0006897; GO:0008429; GO:0031210; GO:0031234; GO:0035091; GO:0042802; GO:0044232; GO:0061817; GO:0140268 17589 XM_044322767.1 11689 7345 4938 10652 3339 Q3TZZ7 6.1e-30 Extended synaptotagmin-2 (E-Syt2) Mus musculus (Mouse) endocytosis [GO:0006897]; endoplasmic reticulum-plasma membrane tethering [GO:0061817]; lipid transport [GO:0006869] GO:0005509; GO:0005544; GO:0005789; GO:0005829; GO:0005886; GO:0006869; GO:0006897; GO:0008429; GO:0031210; GO:0031234; GO:0035091; GO:0042802; GO:0044232; GO:0061817; GO:0140268 17590 XM_044323329.1 220 131 122 377 504 Q9HAR2 2.04e-77 Adhesion G protein-coupled receptor L3 (Calcium-independent alpha-latrotoxin receptor 3) (CIRL-3) (Latrophilin-3) (Lectomedin-3) Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; brain development [GO:0007420]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; G protein-coupled receptor signaling pathway [GO:0007186]; neuron migration [GO:0001764]; synapse assembly [GO:0007416] GO:0001764; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007166; GO:0007186; GO:0007189; GO:0007416; GO:0007420; GO:0016020; GO:0030246; GO:0030424; GO:0098742; GO:0098978 17591 XM_029331462.2 114 80 106 199 60 NA NA NA NA NA NA 17592 XM_029348561.2 72 41 8 34 102 Q96RW7 2.62e-21 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 17593 XM_029348168.2 0 0 19 96 0 Q6NW96 2.27e-79 Transcription factor Sp9 Danio rerio (Zebrafish) (Brachydanio rerio) embryonic limb morphogenesis [GO:0030326]; embryonic pectoral fin morphogenesis [GO:0035118]; positive regulation of fibroblast growth factor receptor signaling pathway [GO:0045743]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0030326; GO:0035118; GO:0045743; GO:0046872 17594 XM_029338575.2 66 125 141 176 216 NA NA NA NA NA NA 17595 XM_029331614.2 0 0 0 0 18 NA NA NA NA NA NA 17596 XM_029351295.2 459 301 414 572 506 Q9QZ85 2.05e-51 Interferon-inducible GTPase 1 (EC 3.6.5.-) Mus musculus (Mouse) cellular response to interferon-beta [GO:0035458]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; regulation of autophagy [GO:0010506]; response to bacterium [GO:0009617] GO:0003924; GO:0005525; GO:0005737; GO:0005789; GO:0006952; GO:0009617; GO:0010506; GO:0019003; GO:0019221; GO:0020005; GO:0031965; GO:0032580; GO:0035458; GO:0042802; GO:0042832; GO:0045087; GO:0050829 17597 XM_044315311.1 19 0 0 0 7 NA NA NA NA NA NA 17598 XM_044311002.1 26 28 11 12 57 NA NA NA NA NA NA 17599 XM_044325807.1 6 1 1 33 12 NA NA NA NA NA NA 17600 XM_029335310.2 1279 1289 724 621 1137 NA NA NA NA NA NA 17601 XM_029352564.2 992 933 424 762 1065 Q6DDF0 0 WD repeat-containing protein 37 Xenopus laevis (African clawed frog) NA GO:0005634; GO:0005737 17602 XM_029351683.2 14 0 8 11 0 NA NA NA NA NA NA 17603 XM_044314923.1 53 0 0 0 0 Q2TBP0 6.26e-42 Proteasome subunit beta type-7 (EC 3.4.25.1) Bos taurus (Bovine) proteolysis involved in protein catabolic process [GO:0051603] GO:0004298; GO:0005634; GO:0005737; GO:0005839; GO:0019774; GO:0051603 17604 XM_044314923.1 53 0 0 0 0 Q2TBP0 6.26e-42 Proteasome subunit beta type-7 (EC 3.4.25.1) Bos taurus (Bovine) proteolysis involved in protein catabolic process [GO:0051603] GO:0004298; GO:0005634; GO:0005737; GO:0005839; GO:0019774; GO:0051603 17605 XM_029342108.2 8 2 10 30 12 B8V7S0 2.57e-54 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 17606 XM_044322148.1 85 16 0 63 0 Q9DCC4 8.22e-75 Pyrroline-5-carboxylate reductase 3 (P5C reductase 3) (P5CR 3) (EC 1.5.1.2) (Pyrroline-5-carboxylate reductase-like protein) Mus musculus (Mouse) cytidine deamination [GO:0009972]; L-proline biosynthetic process [GO:0055129] GO:0004126; GO:0004735; GO:0005829; GO:0009972; GO:0045171; GO:0055129; GO:0072686 17607 XM_044325146.1 380 152 155 128 283 NA NA NA NA NA NA 17608 XM_029343938.2 139 0 60 110 198 NA NA NA NA NA NA 17609 XM_044328708.1 229 208 41 271 95 B5X4E0 1.35e-39 Calumenin-B Salmo salar (Atlantic salmon) NA GO:0005509; GO:0005576; GO:0005789; GO:0005794; GO:0033018; GO:0042470 17610 XR_006397754.1 211 196 133 262 337 Q0R4F1 1.3e-26 ATP-dependent DNA helicase PIF1 (EC 3.6.4.12) (DNA repair and recombination helicase PIF1) Xenopus laevis (African clawed frog) DNA recombination [GO:0006310]; DNA repair [GO:0006281]; mitochondrial genome maintenance [GO:0000002]; telomere maintenance [GO:0000723] GO:0000002; GO:0000723; GO:0003677; GO:0005524; GO:0005634; GO:0005739; GO:0006281; GO:0006310; GO:0016887; GO:0043139 17611 XM_044320236.1 6 0 0 0 36 P17892 8.11e-50 Pancreatic lipase-related protein 2 (PL-RP2) (Cytotoxic T lymphocyte lipase) (Galactolipase) (EC 3.1.1.26) (Triacylglycerol lipase) (EC 3.1.1.3) Mus musculus (Mouse) cellular defense response [GO:0006968]; galactolipid catabolic process [GO:0019376]; intestinal lipid catabolic process [GO:0044258]; lipid catabolic process [GO:0016042]; phosphatidylcholine catabolic process [GO:0034638]; phospholipid catabolic process [GO:0009395]; phospholipid metabolic process [GO:0006644]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433] GO:0004620; GO:0004806; GO:0005509; GO:0005615; GO:0006644; GO:0006968; GO:0009395; GO:0009617; GO:0016042; GO:0016298; GO:0019376; GO:0019433; GO:0034638; GO:0042589; GO:0043005; GO:0044258; GO:0047372; GO:0047714; GO:0102549 17612 XR_006393200.1 22 8 2 11 21 NA NA NA NA NA NA 17613 XM_044318762.1 125 0 34 146 118 P52826 0 Carnitine O-acetyltransferase (Carnitine acetylase) (EC 2.3.1.137) (EC 2.3.1.7) (Carnitine acetyltransferase) (CAT) (CrAT) Columba livia (Rock dove) carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; medium-chain fatty acid metabolic process [GO:0051791]; short-chain fatty acid metabolic process [GO:0046459] GO:0003997; GO:0004092; GO:0005743; GO:0005777; GO:0005783; GO:0008458; GO:0019254; GO:0033540; GO:0046459; GO:0051791 17614 XM_044320398.1 106 81 107 258 191 NA NA NA NA NA NA 17615 XM_044307239.1 27 16 27 45 30 NA NA NA NA NA NA 17616 XM_029342544.2 25 99 12 62 40 Q9EQD2 1.8e-33 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 17617 XM_029327035.2 203 201 108 125 220 Q01664 3.36e-29 Transcription factor AP-4 (Activating enhancer-binding protein 4) (Class C basic helix-loop-helix protein 41) (bHLHc41) Homo sapiens (Human) cellular response to dexamethasone stimulus [GO:0071549]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of DNA-templated transcription [GO:0045893]; protein-containing complex assembly [GO:0065003]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000785; GO:0000976; GO:0000978; GO:0000981; GO:0001228; GO:0003677; GO:0005634; GO:0005654; GO:0005739; GO:0006357; GO:0006978; GO:0008285; GO:0010629; GO:0017053; GO:0042803; GO:0042826; GO:0043065; GO:0043392; GO:0043565; GO:0043922; GO:0043923; GO:0045736; GO:0045892; GO:0045893; GO:0065003; GO:0070888; GO:0071549; GO:1901990; GO:1990837; GO:2001269 17618 XM_029349426.2 3 3 0 24 20 P20420 5.97e-64 Neuronal acetylcholine receptor subunit alpha-5 Rattus norvegicus (Rat) behavioral response to nicotine [GO:0035095]; cellular response to nicotine [GO:0071316]; chemical synaptic transmission [GO:0007268]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; hippocampus development [GO:0021766]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system process [GO:0050877]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of membrane potential [GO:0042391]; regulation of neuronal action potential [GO:0098908]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to nicotine [GO:0035094]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271] GO:0005231; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0007271; GO:0015464; GO:0021766; GO:0022848; GO:0030425; GO:0030594; GO:0034220; GO:0035094; GO:0035095; GO:0042166; GO:0042391; GO:0043005; GO:0043025; GO:0044877; GO:0045202; GO:0045211; GO:0050877; GO:0050966; GO:0051899; GO:0071316; GO:0098691; GO:0098793; GO:0098908; GO:0099171; GO:1904315; GO:2000300 17619 XR_006396964.1 668 2572 789 4037 1318 B8UU74 1.14e-47 Uncharacterized skeletal organic matrix protein 4 (Uncharacterized SOMP-4) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 17620 XR_006396964.1 668 2572 789 4037 1318 B8UU74 1.14e-47 Uncharacterized skeletal organic matrix protein 4 (Uncharacterized SOMP-4) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 17621 XM_044311481.1 9 1 13 54 1 NA NA NA NA NA NA 17622 XM_029331795.2 454 393 220 255 405 O02776 0 Poly(ADP-ribose) glycohydrolase (EC 3.2.1.143) Bos taurus (Bovine) ATP generation from poly-ADP-D-ribose [GO:1990966]; carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide-sugar metabolic process [GO:0009225]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056] GO:0004649; GO:0005634; GO:0005737; GO:0005975; GO:0006282; GO:0006974; GO:0009225; GO:0031056; GO:1990966 17623 XM_044307061.1 845 592 495 871 763 Q9QYE6 6.22e-116 Golgin subfamily A member 5 (Golgin-84) (Protein Ret-II) (Protein Sumiko) Mus musculus (Mouse) Golgi organization [GO:0007030]; Golgi vesicle transport [GO:0048193]; retrograde transport, vesicle recycling within Golgi [GO:0000301] GO:0000137; GO:0000138; GO:0000139; GO:0000301; GO:0005794; GO:0005797; GO:0005801; GO:0007030; GO:0016020; GO:0030663; GO:0030674; GO:0031267; GO:0031985; GO:0042803; GO:0048193 17624 XM_029328737.2 208 626 191 146 11 Q55FU9 6.09e-36 Ras-related protein Rab-24 Dictyostelium discoideum (Social amoeba) autophagy [GO:0006914]; intracellular protein transport [GO:0006886] GO:0003924; GO:0005525; GO:0005768; GO:0005776; GO:0005783; GO:0005793; GO:0005794; GO:0006886; GO:0006914; GO:0012505; GO:0016020; GO:0030139 17625 XM_044307929.1 126 70 78 312 483 NA NA NA NA NA NA 17626 XR_006393202.1 12 3 5 11 11 NA NA NA NA NA NA 17627 XM_029334436.2 4 0 11 4 13 Q09575 2.78e-30 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 17628 XM_044326057.1 1298 297 779 1164 1110 P98088 3.16e-112 Mucin-5AC (MUC-5AC) (Gastric mucin) (Major airway glycoprotein) (Mucin-5 subtype AC, tracheobronchial) (Tracheobronchial mucin) (TBM) Homo sapiens (Human) phosphatidylinositol-mediated signaling [GO:0048015] GO:0005201; GO:0005615; GO:0005737; GO:0005796; GO:0005886; GO:0031012; GO:0048015; GO:0070062; GO:0070701 17629 XM_044326057.1 1298 297 779 1164 1110 P98088 3.73e-21 Mucin-5AC (MUC-5AC) (Gastric mucin) (Major airway glycoprotein) (Mucin-5 subtype AC, tracheobronchial) (Tracheobronchial mucin) (TBM) Homo sapiens (Human) phosphatidylinositol-mediated signaling [GO:0048015] GO:0005201; GO:0005615; GO:0005737; GO:0005796; GO:0005886; GO:0031012; GO:0048015; GO:0070062; GO:0070701 17630 XM_044312380.1 0 61 90 6 36 NA NA NA NA NA NA 17631 XM_044320043.1 1676 1841 1172 2396 1116 B8EIZ7 1.06e-162 NA NA NA NA 17632 XM_044307185.1 0 0 0 11 0 Q8BGY6 2.74e-21 Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase (EC 2.4.1.206) (Lactotriaosylceramide synthase) (Lc(3)Cer synthase) (Lc3 synthase) (UDP-GlcNAc:beta-Gal beta-1,3-N-acetylglucosaminyltransferase 5) (BGnT-5) (Beta-1,3-Gn-T5) (Beta-1,3-N-acetylglucosaminyltransferase 5) (Beta3Gn-T5) Mus musculus (Mouse) brain development [GO:0007420]; central nervous system development [GO:0007417]; protein glycosylation [GO:0006486]; sphingolipid biosynthetic process [GO:0030148] GO:0000139; GO:0006486; GO:0007417; GO:0007420; GO:0008457; GO:0016757; GO:0030148; GO:0047256 17633 XM_044320810.1 0 52 6 220 73 NA NA NA NA NA NA 17634 XM_029328870.2 703 440 391 547 461 Q9H3R0 1.1e-156 Lysine-specific demethylase 4C (EC 1.14.11.66) (Gene amplified in squamous cell carcinoma 1 protein) (GASC-1 protein) (JmjC domain-containing histone demethylation protein 3C) (Jumonji domain-containing protein 2C) ([histone H3]-trimethyl-L-lysine(9) demethylase 4C) Homo sapiens (Human) blastocyst formation [GO:0001825]; chromatin remodeling [GO:0006338]; histone H3-K9 demethylation [GO:0033169]; positive regulation of cell population proliferation [GO:0008284]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of stem cell differentiation [GO:2000736]; regulation of transcription by RNA polymerase II [GO:0006357]; stem cell population maintenance [GO:0019827] GO:0000785; GO:0001825; GO:0005634; GO:0005654; GO:0005721; GO:0006338; GO:0006357; GO:0008270; GO:0008284; GO:0019827; GO:0019899; GO:0032452; GO:0032454; GO:0033169; GO:0050681; GO:0051864; GO:0060765; GO:0140684; GO:2000736 17635 XM_029328870.2 703 440 391 547 461 Q9H3R0 3.65e-74 Lysine-specific demethylase 4C (EC 1.14.11.66) (Gene amplified in squamous cell carcinoma 1 protein) (GASC-1 protein) (JmjC domain-containing histone demethylation protein 3C) (Jumonji domain-containing protein 2C) ([histone H3]-trimethyl-L-lysine(9) demethylase 4C) Homo sapiens (Human) blastocyst formation [GO:0001825]; chromatin remodeling [GO:0006338]; histone H3-K9 demethylation [GO:0033169]; positive regulation of cell population proliferation [GO:0008284]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of stem cell differentiation [GO:2000736]; regulation of transcription by RNA polymerase II [GO:0006357]; stem cell population maintenance [GO:0019827] GO:0000785; GO:0001825; GO:0005634; GO:0005654; GO:0005721; GO:0006338; GO:0006357; GO:0008270; GO:0008284; GO:0019827; GO:0019899; GO:0032452; GO:0032454; GO:0033169; GO:0050681; GO:0051864; GO:0060765; GO:0140684; GO:2000736 17636 XM_029337279.2 139 81 64 39 483 A6NFN3 3.02e-36 RNA binding protein fox-1 homolog 3 (Fox-1 homolog C) (Neuronal nuclei antigen) (NeuN antigen) Homo sapiens (Human) mRNA processing [GO:0006397]; nervous system development [GO:0007399]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380] GO:0000381; GO:0003729; GO:0005634; GO:0005737; GO:0006397; GO:0007399; GO:0008380 17637 XM_029341854.2 2831 1359 1391 1237 1967 NA NA NA NA NA NA 17638 XR_006396387.1 44 16 113 41 611 NA NA NA NA NA NA 17639 XM_029357454.2 2622 2239 1779 1719 1670 NA NA NA NA NA NA 17640 XM_044316223.1 15 37 4 22 18 NA NA NA NA NA NA 17641 XM_029353892.2 276 240 177 261 212 NA NA NA NA NA NA 17642 XM_044322121.1 54 0 10 75 44 Q8IYF3 1.74e-133 Testis-expressed protein 11 (Protein ZIP4 homolog) (ZIP4H) Homo sapiens (Human) apoptotic process [GO:0006915]; chiasma assembly [GO:0051026]; ectopic germ cell programmed cell death [GO:0035234]; fertilization [GO:0009566]; male gonad development [GO:0008584]; male meiosis chromosome segregation [GO:0007060]; meiotic gene conversion [GO:0006311]; negative regulation of apoptotic process [GO:0043066]; negative regulation of developmental process [GO:0051093]; negative regulation of reproductive process [GO:2000242]; reciprocal meiotic recombination [GO:0007131]; resolution of meiotic recombination intermediates [GO:0000712]; synaptonemal complex assembly [GO:0007130] GO:0000712; GO:0000801; GO:0005694; GO:0006311; GO:0006915; GO:0007060; GO:0007130; GO:0007131; GO:0008584; GO:0009566; GO:0035234; GO:0043066; GO:0051026; GO:0051093; GO:2000242 17643 XM_029339764.2 611 330 203 710 195 Q861W0 2.49e-28 NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like protein) (I-kappa-B-like protein) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1) Pan troglodytes (Chimpanzee) cellular response to lipopolysaccharide [GO:0071222]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; negative regulation of tumor necrosis factor production [GO:0032720] GO:0005634; GO:0007249; GO:0031665; GO:0032088; GO:0032720; GO:0034122; GO:0071222 17644 XM_029348942.2 103 69 23 54 63 O54852 3.75e-100 Potassium voltage-gated channel subfamily H member 7 (Ether-a-go-go-related gene potassium channel 3) (ERG-3) (Eag-related protein 3) (Ether-a-go-go-related protein 3) (Voltage-gated potassium channel subunit Kv11.3) Rattus norvegicus (Rat) circadian rhythm [GO:0007623]; membrane repolarization during action potential [GO:0086011]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391] GO:0005242; GO:0005249; GO:0005267; GO:0005886; GO:0006813; GO:0007623; GO:0034765; GO:0042391; GO:0044877; GO:0071805; GO:0086011 17645 XR_006397756.1 43 18 88 63 156 NA NA NA NA NA NA 17646 XM_029327994.2 0 1524 0 0 0 NA NA NA NA NA NA 17647 XM_029331640.2 0 6 1 6 3 NA NA NA NA NA NA 17648 XR_006392923.1 41 2 25 5 151 NA NA NA NA NA NA 17649 XM_044325628.1 495 293 301 388 619 A9UMG5 2.46e-78 Protein IMPACT-B (Imprinted and ancient gene protein homolog B) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cellular response to acidic pH [GO:0071468]; cellular response to amino acid starvation [GO:0034198]; cellular response to benomyl [GO:0072755]; cellular response to glucose starvation [GO:0042149]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to leucine starvation [GO:1990253]; cellular response to UV-C [GO:0071494]; GCN2-mediated signaling [GO:0140469]; negative regulation of cell death [GO:0060548]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; neuron projection extension [GO:1990138]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of translational initiation in response to starvation [GO:0071264] GO:0000122; GO:0001933; GO:0005737; GO:0005844; GO:0031333; GO:0031953; GO:0034198; GO:0042149; GO:0045666; GO:0060548; GO:0070301; GO:0071264; GO:0071468; GO:0071494; GO:0072755; GO:0097201; GO:0140469; GO:1990138; GO:1990253 17650 XM_029339142.2 0 6 0 0 0 Q9VXN0 1.27e-91 Glycosyltransferase-like domain-containing protein 1-like Drosophila melanogaster (Fruit fly) NA GO:0016757 17651 XM_044312011.1 131 26 130 209 75 Q95LR0 1.17e-33 Cilia- and flagella-associated protein 91 (CFAP91) (AMY-1-associating protein expressed in testis 1) (AAT-1) (MYCBP/AMY-1-associated testis-expressed protein 1) (Protein MAATS1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) axonemal central apparatus assembly [GO:1904158]; cell differentiation [GO:0030154]; cilium movement [GO:0003341]; spermatogenesis [GO:0007283] GO:0003341; GO:0005739; GO:0005930; GO:0007283; GO:0030154; GO:0031514; GO:1904158 17652 XM_044312011.1 131 26 130 209 75 Q95LR0 1.17e-33 Cilia- and flagella-associated protein 91 (CFAP91) (AMY-1-associating protein expressed in testis 1) (AAT-1) (MYCBP/AMY-1-associated testis-expressed protein 1) (Protein MAATS1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) axonemal central apparatus assembly [GO:1904158]; cell differentiation [GO:0030154]; cilium movement [GO:0003341]; spermatogenesis [GO:0007283] GO:0003341; GO:0005739; GO:0005930; GO:0007283; GO:0030154; GO:0031514; GO:1904158 17653 XM_029347711.2 648 2211 576 1814 1000 NA NA NA NA NA NA 17654 XM_029351460.2 247 202 50 0 0 NA NA NA NA NA NA 17655 XM_044315182.1 320 178 32 443 97 NA NA NA NA NA NA 17656 XM_029358149.2 10 29 2 12 8 NA NA NA NA NA NA 17657 XM_044310240.1 0 0 14 16 44 NA NA NA NA NA NA 17658 XM_044324852.1 58 17 62 6 143 NA NA NA NA NA NA 17659 XR_006395497.1 34 15 26 15 0 NA NA NA NA NA NA 17660 XM_029353092.2 765 418 362 445 628 NA NA NA NA NA NA 17661 XM_029349013.2 0 96 76 194 494 P58307 1.93e-31 Orexin/Hypocretin receptor type 1 (Hypocretin receptor type 1) (Orexin receptor type 1) (Ox-1-R) (Ox1-R) (Ox1R) Mus musculus (Mouse) feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0004930; GO:0005886; GO:0007186; GO:0007218; GO:0007631; GO:0016499; GO:0017046; GO:0051480; GO:0070374 17662 XM_044324604.1 2 10 4 3 28 NA NA NA NA NA NA 17663 XM_029336839.2 28 6 0 9 26 O42409 9.37e-96 Zinc finger protein Gfi-1b (Growth factor-independent protein 1B) Gallus gallus (Chicken) chromatin organization [GO:0006325]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001227; GO:0005654; GO:0006325; GO:0006357; GO:0046872 17664 XM_029336839.2 28 6 0 9 26 O42409 1.41e-21 Zinc finger protein Gfi-1b (Growth factor-independent protein 1B) Gallus gallus (Chicken) chromatin organization [GO:0006325]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001227; GO:0005654; GO:0006325; GO:0006357; GO:0046872 17665 XM_029350502.2 157 0 99 167 88 NA NA NA NA NA NA 17666 XM_044319855.1 341 307 0 352 158 Q8MIQ9 4.66e-125 P protein (Melanocyte-specific transporter protein) (Pink-eyed dilution protein homolog) Sus scrofa (Pig) lysosomal lumen pH elevation [GO:0035752]; melanin biosynthetic process [GO:0042438]; melanin biosynthetic process from tyrosine [GO:0006583]; melanocyte differentiation [GO:0030318] GO:0006583; GO:0030318; GO:0033162; GO:0035752; GO:0042438; GO:0061778 17667 XM_029331998.2 0 3 0 36 0 NA NA NA NA NA NA 17668 XM_029352411.2 791 941 528 1176 599 Q5RHX6 6.39e-87 DCN1-like protein 4 (DCNL4) (DCUN1 domain-containing protein 4) (Defective in cullin neddylation protein 1-like protein 4) Danio rerio (Zebrafish) (Brachydanio rerio) positive regulation of protein neddylation [GO:2000436]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein neddylation [GO:0045116] GO:0000151; GO:0005634; GO:0031624; GO:0032182; GO:0045116; GO:0051443; GO:0097602; GO:2000436 17669 XM_044320955.1 735 31 31 165 939 Q9JMJ2 3.53e-83 F-box/WD repeat-containing protein 4 (F-box and WD-40 domain-containing protein 4) (Protein hagoromo) Mus musculus (Mouse) cartilage development [GO:0051216]; embryonic digit morphogenesis [GO:0042733]; limb development [GO:0060173]; positive regulation of mesenchymal cell proliferation [GO:0002053]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; Wnt signaling pathway [GO:0016055] GO:0002053; GO:0016055; GO:0019005; GO:0031146; GO:0042733; GO:0051216; GO:0060173 17670 XM_029349844.2 305 161 149 188 376 Q0VA04 3.69e-97 Nonsense-mediated mRNA decay factor SMG8 (Protein smg-8 homolog) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of protein kinase activity [GO:0045859] GO:0000184; GO:0045859 17671 XM_029349844.2 305 161 149 188 376 Q0VA04 4.38e-31 Nonsense-mediated mRNA decay factor SMG8 (Protein smg-8 homolog) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of protein kinase activity [GO:0045859] GO:0000184; GO:0045859 17672 XM_029334885.2 85 0 0 97 98 O42574 5.84e-24 Beta-1 adrenergic receptor (Beta-1 adrenoreceptor) (Beta-1 adrenoceptor) (x-BETA1AR) Xenopus laevis (African clawed frog) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; positive regulation of GTPase activity [GO:0043547]; positive regulation of heart contraction [GO:0045823] GO:0004940; GO:0005085; GO:0005769; GO:0005886; GO:0043547; GO:0045823; GO:0071880 17673 XM_044316951.1 42 0 29 0 31 G3M4F8 1.07e-45 Octopamine receptor beta-2R (CsOA2B2) Chilo suppressalis (Asiatic rice borer moth) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cellular response to amine stimulus [GO:0071418]; octopamine signaling pathway [GO:0071927]; tyramine signaling pathway [GO:0071928] GO:0004989; GO:0005886; GO:0007189; GO:0008226; GO:0016020; GO:0071418; GO:0071927; GO:0071928 17674 XM_044327585.1 25 58 28 0 161 A7YSY2 0 Ribosome biogenesis protein SPATA5L1 (EC 3.6.4.10) (Spermatogenesis-associated protein 5-like protein 1) Bos taurus (Bovine) ribosomal large subunit biogenesis [GO:0042273] GO:0005524; GO:0005634; GO:0005737; GO:0005819; GO:0016887; GO:0042273; GO:1990275 17675 XR_006394089.1 34 21 49 9 67 NA NA NA NA NA NA 17676 XR_006393998.1 540 265 142 431 854 A3KN83 0 Protein strawberry notch homolog 1 (Monocyte protein 3) (MOP-3) Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355]; regulation of response to stimulus [GO:0048583] GO:0005634; GO:0006355; GO:0031490; GO:0042393; GO:0048583 17677 XR_006393998.1 540 265 142 431 854 A3KN83 0 Protein strawberry notch homolog 1 (Monocyte protein 3) (MOP-3) Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355]; regulation of response to stimulus [GO:0048583] GO:0005634; GO:0006355; GO:0031490; GO:0042393; GO:0048583 17678 XR_006393998.1 540 265 142 431 854 A3KN83 0 Protein strawberry notch homolog 1 (Monocyte protein 3) (MOP-3) Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355]; regulation of response to stimulus [GO:0048583] GO:0005634; GO:0006355; GO:0031490; GO:0042393; GO:0048583 17679 XM_044310236.1 130 47 85 163 192 NA NA NA NA NA NA 17680 XM_029327401.2 532 411 201 340 238 Q96LK0 1.19e-34 Centrosomal protein of 19 kDa (Cep19) Homo sapiens (Human) cilium assembly [GO:0060271]; microtubule anchoring at centrosome [GO:0034454]; vesicle targeting, trans-Golgi to periciliary membrane compartment [GO:0097712] GO:0000922; GO:0005654; GO:0005737; GO:0005813; GO:0005814; GO:0005929; GO:0034454; GO:0036064; GO:0060271; GO:0097712 17681 XM_029354182.2 0 0 26 0 0 Q29599 7.77e-41 2'-5'-oligoadenylate synthase 1 ((2-5')oligo(A) synthase 1) (2-5A synthase 1) (EC 2.7.7.84) (p42 OAS) Sus scrofa (Pig) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; regulation of ribonuclease activity [GO:0060700] GO:0001730; GO:0003725; GO:0005524; GO:0005576; GO:0005654; GO:0005737; GO:0005739; GO:0005783; GO:0005829; GO:0016020; GO:0045071; GO:0045087; GO:0046872; GO:0051607; GO:0060700 17682 XR_006391605.1 90 122 64 103 224 NA NA NA NA NA NA 17683 XR_006398058.1 0 0 0 33 0 NA NA NA NA NA NA 17684 XM_029358038.2 3397 1977 1189 2860 4872 P31646 0 Sodium- and chloride-dependent GABA transporter 2 (GAT-2) (Solute carrier family 6 member 13) Rattus norvegicus (Rat) amino acid import across plasma membrane [GO:0089718]; creatine transmembrane transport [GO:0015881]; gamma-aminobutyric acid import [GO:0051939]; monocarboxylic acid transport [GO:0015718]; neurotransmitter transport [GO:0006836]; nitrogen compound transport [GO:0071705]; positive regulation of necrotic cell death [GO:0010940]; sodium ion transmembrane transport [GO:0035725]; taurine transport [GO:0015734] GO:0005283; GO:0005308; GO:0005332; GO:0005368; GO:0005369; GO:0005886; GO:0006836; GO:0008028; GO:0010940; GO:0015171; GO:0015185; GO:0015718; GO:0015734; GO:0015881; GO:0016323; GO:0035725; GO:0042165; GO:0043005; GO:0051939; GO:0071705; GO:0089718 17685 XM_029332900.2 918 54 597 970 0 NA NA NA NA NA NA 17686 XM_044318578.1 51 0 57 14 0 NA NA NA NA NA NA 17687 XM_044316683.1 236 259 73 453 152 NA NA NA NA NA NA 17688 XM_029357023.2 6465 6349 5209 6679 4721 D3Z3C6 2.06e-86 AN1-type zinc finger protein 4 (AN1-type zinc finger and ubiquitin domain-containing protein-like 1) Mus musculus (Mouse) NA GO:0008270 17689 XM_029357023.2 6465 6349 5209 6679 4721 D3Z3C6 2.98e-26 AN1-type zinc finger protein 4 (AN1-type zinc finger and ubiquitin domain-containing protein-like 1) Mus musculus (Mouse) NA GO:0008270 17690 XR_003827178.2 15 43 15 56 32 NA NA NA NA NA NA 17691 XM_029344620.2 813 1080 599 1379 677 Q9MYU8 1.26e-97 Band 4.1-like protein 5 (Erythrocyte membrane protein band 4.1-like 5) Canis lupus familiaris (Dog) (Canis familiaris) actomyosin structure organization [GO:0031032] GO:0001917; GO:0005737; GO:0005856; GO:0005886; GO:0005912; GO:0008092; GO:0031032 17692 XR_003825859.2 2 0 33 1 28 NA NA NA NA NA NA 17693 XM_029346304.2 0 0 3 0 108 Q6L8S8 1.84e-57 Beta-1,4-N-acetylgalactosaminyltransferase 3 (Beta4GalNAc-T3) (Beta4GalNAcT3) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase III) (N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 2) (NGalNAc-T2) Mus musculus (Mouse) chondroitin sulfate biosynthetic process [GO:0030206] GO:0005794; GO:0008376; GO:0030206; GO:0032580; GO:0033842; GO:0043231; GO:0047238 17694 XM_044328145.1 25 5 8 5 52 NA NA NA NA NA NA 17695 XM_044308115.1 99 113 71 60 114 O00471 1.03e-61 Exocyst complex component 5 (Exocyst complex component Sec10) (hSec10) Homo sapiens (Human) epithelial cell apoptotic process [GO:1904019]; establishment of planar polarity [GO:0001736]; exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; membrane fission [GO:0090148]; mitotic cytokinesis [GO:0000281]; non-motile cilium assembly [GO:1905515]; post-Golgi vesicle-mediated transport [GO:0006892]; protein localization to plasma membrane [GO:0072659]; protein transport [GO:0015031]; vesicle docking involved in exocytosis [GO:0006904]; vesicle tethering involved in exocytosis [GO:0090522] GO:0000145; GO:0000281; GO:0001736; GO:0005737; GO:0005829; GO:0006887; GO:0006892; GO:0006893; GO:0006904; GO:0015031; GO:0030496; GO:0031267; GO:0047485; GO:0072659; GO:0090148; GO:0090522; GO:1904019; GO:1905515 17696 XM_029357164.2 0 0 17 0 0 NA NA NA NA NA NA 17697 XM_044307595.1 473 222 1621 135 691 NA NA NA NA NA NA 17698 XM_029355482.2 576 400 449 1093 509 O54928 1.52e-55 Suppressor of cytokine signaling 5 (SOCS-5) (Cytokine-inducible SH2-containing protein 5) Mus musculus (Mouse) cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cytokine-mediated signaling pathway [GO:0019221]; epidermal growth factor receptor signaling pathway [GO:0007173]; intracellular signal transduction [GO:0035556]; negative regulation of endothelial cell activation [GO:1904988]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of signal transduction [GO:0009968]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; phosphatidylinositol phosphate biosynthetic process [GO:0046854]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of T-helper 1 cell differentiation [GO:0045627]; protein ubiquitination [GO:0016567]; receptor signaling pathway via JAK-STAT [GO:0007259]; vascular endothelial cell response to fluid shear stress [GO:0097699] GO:0005154; GO:0005737; GO:0005942; GO:0007173; GO:0007175; GO:0007259; GO:0009968; GO:0016567; GO:0019210; GO:0019221; GO:0030971; GO:0032436; GO:0032715; GO:0035556; GO:0045627; GO:0045629; GO:0046854; GO:0046935; GO:0050728; GO:0071404; GO:0071638; GO:0097699; GO:1904988 17699 XM_029348844.2 67 93 90 67 105 NA NA NA NA NA NA 17700 XM_044318614.1 0 1 2 11 7 NA NA NA NA NA NA 17701 XR_006392317.1 3 1 4 30 0 NA NA NA NA NA NA 17702 XM_044319379.1 10 6 2 7 0 NA NA NA NA NA NA 17703 XM_029357214.2 740 512 378 471 530 Q9HCJ3 3.38e-44 Ribonucleoprotein PTB-binding 2 (Protein raver-2) Homo sapiens (Human) regulation of alternative mRNA splicing, via spliceosome [GO:0000381] GO:0000381; GO:0003723; GO:0003729; GO:0005634; GO:0005737 17704 XM_029351275.2 2387 2266 1372 2087 2399 Q4R4R0 0 26S proteasome regulatory subunit 7 (26S proteasome AAA-ATPase subunit RPT1) (Proteasome 26S subunit ATPase 2) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000502; GO:0000932; GO:0005524; GO:0005634; GO:0005829; GO:0006511; GO:0016887; GO:0022624; GO:0036402 17705 XM_029348527.2 0 494 0 0 0 P00521 3.68e-27 Tyrosine-protein kinase transforming protein Abl (EC 2.7.10.2) (V-abl) Abelson murine leukemia virus NA GO:0004715; GO:0005524 17706 XM_029349961.2 2861 1868 1641 2922 2649 O00409 3.85e-48 Forkhead box protein N3 (Checkpoint suppressor 1) Homo sapiens (Human) craniofacial suture morphogenesis [GO:0097094]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; negative regulation of DNA-templated transcription [GO:0045892]; regulation of DNA-templated transcription [GO:0006355] GO:0000785; GO:0000981; GO:0000987; GO:0003700; GO:0005634; GO:0006355; GO:0007095; GO:0008022; GO:0045892; GO:0097094 17707 XM_044317705.1 364 389 356 405 345 NA NA NA NA NA NA 17708 XR_003824871.2 26 15 15 17 16 NA NA NA NA NA NA 17709 XR_006392489.1 338 110 100 157 361 NA NA NA NA NA NA 17710 XM_044310001.1 0 0 14 1 0 NA NA NA NA NA NA 17711 XM_044308205.1 817 1021 541 931 1011 NA NA NA NA NA NA 17712 XM_029339965.2 5 1 7 0 0 NA NA NA NA NA NA 17713 XM_029330298.2 235 167 160 169 298 Q5ZLS8 1.39e-103 Integrator complex subunit 10 (Int10) Gallus gallus (Chicken) snRNA processing [GO:0016180] GO:0016180; GO:0032039 17714 XM_029358603.2 629 59 256 442 503 Q8TF05 1.31e-107 Serine/threonine-protein phosphatase 4 regulatory subunit 1 Homo sapiens (Human) protein dephosphorylation [GO:0006470]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165] GO:0006468; GO:0006470; GO:0007165; GO:0019888; GO:0030289 17715 XM_029358603.2 629 59 256 442 503 Q8TF05 1.18e-92 Serine/threonine-protein phosphatase 4 regulatory subunit 1 Homo sapiens (Human) protein dephosphorylation [GO:0006470]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165] GO:0006468; GO:0006470; GO:0007165; GO:0019888; GO:0030289 17716 XM_044315544.1 161 10 103 68 9 NA NA NA NA NA NA 17717 XM_044319373.1 19 25 62 224 38 NA NA NA NA NA NA 17718 XR_003822925.2 414 220 93 349 163 NA NA NA NA NA NA 17719 XR_006392613.1 15 3 0 12 0 NA NA NA NA NA NA 17720 XM_044311329.1 7 2 15 10 14 NA NA NA NA NA NA 17721 XR_003827494.2 53 21 2 6 18 NA NA NA NA NA NA 17722 XM_029343510.2 146 111 24 66 82 Q8CBH5 6.34e-73 Major facilitator superfamily domain-containing protein 6 (Macrophage MHC class I receptor 2) Mus musculus (Mouse) adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590] GO:0002250; GO:0005886; GO:0016020; GO:0032393; GO:0042288; GO:0042590 17723 XM_029343510.2 146 111 24 66 82 Q8CBH5 8.46e-62 Major facilitator superfamily domain-containing protein 6 (Macrophage MHC class I receptor 2) Mus musculus (Mouse) adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590] GO:0002250; GO:0005886; GO:0016020; GO:0032393; GO:0042288; GO:0042590 17724 XR_006394176.1 41 106 0 22 15 NA NA NA NA NA NA 17725 XR_003827029.2 10 11 8 10 12 NA NA NA NA NA NA 17726 XM_029344038.2 10 40 0 63 0 NA NA NA NA NA NA 17727 XM_044328475.1 13 0 0 0 9 O42127 1.47e-58 Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) Xenopus laevis (African clawed frog) apoptotic process [GO:0006915]; positive regulation of cell population proliferation [GO:0008284] GO:0005007; GO:0005524; GO:0005886; GO:0006915; GO:0008284 17728 XM_044321818.1 0 0 3 3 6 P49288 6.11e-23 Melatonin receptor type 1C (Mel-1C-R) (Mel1c receptor) (CKB) Gallus gallus (Chicken) G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of glucose import [GO:0046325]; negative regulation of glycolytic process [GO:0045820] GO:0004930; GO:0005654; GO:0005886; GO:0007186; GO:0008502; GO:0045820; GO:0046325; GO:1904408 17729 XM_044316540.1 37 18 75 117 265 Q8BP78 3.29e-70 Protein FRA10AC1 homolog Mus musculus (Mouse) dephosphorylation [GO:0016311] GO:0005634; GO:0016311; GO:0016791 17730 XM_029333461.2 1 0 0 45 7 P98192 5.93e-105 Dihydroxyacetone phosphate acyltransferase (DAP-AT) (DHAP-AT) (EC 2.3.1.42) (Acyl-CoA:dihydroxyacetonephosphateacyltransferase) (Glycerone-phosphate O-acyltransferase) Mus musculus (Mouse) cerebellum morphogenesis [GO:0021587]; ether lipid biosynthetic process [GO:0008611]; fatty acid metabolic process [GO:0006631]; glycerophospholipid metabolic process [GO:0006650]; membrane organization [GO:0061024]; myelination [GO:0042552]; paranodal junction assembly [GO:0030913]; phospholipid biosynthetic process [GO:0008654]; response to fatty acid [GO:0070542]; response to nutrient [GO:0007584]; response to starvation [GO:0042594]; response to xenobiotic stimulus [GO:0009410]; synapse assembly [GO:0007416] GO:0003824; GO:0005739; GO:0005777; GO:0005778; GO:0005782; GO:0006631; GO:0006650; GO:0007416; GO:0007584; GO:0008611; GO:0008654; GO:0009410; GO:0016287; GO:0021587; GO:0030913; GO:0031966; GO:0042552; GO:0042594; GO:0061024; GO:0070542 17731 XM_029357881.2 49 19 34 0 0 Q8BGC1 3.35e-60 UPF0489 protein C5orf22 homolog Mus musculus (Mouse) NA NA 17732 XM_029328901.2 45 0 34 0 11 Q9Y547 2.56e-27 Intraflagellar transport protein 25 homolog (Heat shock protein beta-11) (Hspb11) (Placental protein 25) (PP25) Homo sapiens (Human) cell differentiation [GO:0030154]; cilium assembly [GO:0060271]; heart development [GO:0007507]; intraciliary anterograde transport [GO:0035720]; kidney development [GO:0001822]; left/right axis specification [GO:0070986]; lung development [GO:0030324]; protein transport [GO:0015031]; skeletal system development [GO:0001501]; smoothened signaling pathway [GO:0007224]; spermatogenesis [GO:0007283] GO:0001501; GO:0001822; GO:0005813; GO:0005929; GO:0007224; GO:0007283; GO:0007507; GO:0015031; GO:0030154; GO:0030324; GO:0030992; GO:0035720; GO:0046872; GO:0060271; GO:0070986; GO:0097542 17733 XM_029358564.2 46 20 0 1 61 NA NA NA NA NA NA 17734 XM_044322683.1 0 4 6 37 3 NA NA NA NA NA NA 17735 XR_006397692.1 2494 2677 1354 1825 1200 Q9JI78 5.34e-92 Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase (PNGase) (mPNGase) (EC 3.5.1.52) (N-glycanase 1) (Peptide:N-glycanase) Mus musculus (Mouse) ER-associated misfolded protein catabolic process [GO:0071712]; glycoprotein catabolic process [GO:0006516]; protein deglycosylation [GO:0006517]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515] GO:0000224; GO:0005634; GO:0005737; GO:0005829; GO:0006515; GO:0006516; GO:0006517; GO:0046872; GO:0062023; GO:0071712 17736 XR_006397692.1 2494 2677 1354 1825 1200 Q9JI78 5.34e-92 Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase (PNGase) (mPNGase) (EC 3.5.1.52) (N-glycanase 1) (Peptide:N-glycanase) Mus musculus (Mouse) ER-associated misfolded protein catabolic process [GO:0071712]; glycoprotein catabolic process [GO:0006516]; protein deglycosylation [GO:0006517]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515] GO:0000224; GO:0005634; GO:0005737; GO:0005829; GO:0006515; GO:0006516; GO:0006517; GO:0046872; GO:0062023; GO:0071712 17737 XR_003825442.2 502 451 356 286 467 NA NA NA NA NA NA 17738 XM_029356130.2 35 2 5 16 139 Q9VCA2 7.81e-59 Organic cation transporter protein Drosophila melanogaster (Fruit fly) apoptotic process [GO:0006915]; ion transport [GO:0006811] GO:0006811; GO:0006915; GO:0016020; GO:0022857 17739 XR_006394045.1 49 41 25 22 63 NA NA NA NA NA NA 17740 XM_029357982.2 143 107 36 93 149 Q4V8B8 9.39e-122 tRNA wybutosine-synthesizing protein 2 homolog (tRNA-yW-synthesizing protein 2) (EC 2.5.1.114) (tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase) Rattus norvegicus (Rat) tRNA methylation [GO:0030488] GO:0005737; GO:0008175; GO:0030488; GO:0102522 17741 XM_044317541.1 105 50 107 49 83 NA NA NA NA NA NA 17742 XR_003826102.2 1 0 0 1 11 NA NA NA NA NA NA 17743 XM_044308444.1 72 41 3 259 0 NA NA NA NA NA NA 17744 XM_044315763.1 91 38 69 103 596 Q15485 2.99e-66 Ficolin-2 (37 kDa elastin-binding protein) (Collagen/fibrinogen domain-containing protein 2) (EBP-37) (Ficolin-B) (Ficolin-beta) (Hucolin) (L-ficolin) (Serum lectin p35) Homo sapiens (Human) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; positive regulation of opsonization [GO:1903028]; proteolysis [GO:0006508]; recognition of apoptotic cell [GO:0043654] GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005576; GO:0005581; GO:0005615; GO:0006508; GO:0008228; GO:0009897; GO:0042802; GO:0043394; GO:0043654; GO:0046872; GO:0048306; GO:0050829; GO:0050830; GO:0062023; GO:0070062; GO:0072562; GO:0097367; GO:1903028; GO:1905370; GO:2001065 17745 XM_044325406.1 0 19 0 14 101 P14740 9.37e-155 Dipeptidyl peptidase 4 (EC 3.4.14.5) (Bile canaliculus domain-specific membrane glycoprotein) (Dipeptidyl peptidase IV) (DPP IV) (GP110 glycoprotein) (T-cell activation antigen CD26) (CD antigen CD26) [Cleaved into: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form); Dipeptidyl peptidase 4 60 kDa soluble form (Dipeptidyl peptidase IV 60 kDa soluble form)] Rattus norvegicus (Rat) B-1a B cell differentiation [GO:0002337]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; establishment of localization [GO:0051234]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; negative regulation of neutrophil chemotaxis [GO:0090024]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of natural killer cell mediated immunity [GO:0002717]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of T cell mediated immunity [GO:0002709]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295] GO:0001618; GO:0001662; GO:0001666; GO:0002020; GO:0002337; GO:0002709; GO:0002717; GO:0004177; GO:0004252; GO:0005102; GO:0005518; GO:0005576; GO:0005783; GO:0005794; GO:0005886; GO:0006508; GO:0007155; GO:0008236; GO:0008239; GO:0008284; GO:0009986; GO:0010716; GO:0016324; GO:0030027; GO:0030139; GO:0030163; GO:0031258; GO:0031295; GO:0033632; GO:0035641; GO:0036343; GO:0042110; GO:0042277; GO:0042802; GO:0042803; GO:0043542; GO:0045121; GO:0045499; GO:0046581; GO:0051234; GO:0090024 17746 XM_044314148.1 0 0 0 83 52 NA NA NA NA NA NA 17747 XM_044309637.1 251 476 103 152 115 NA NA NA NA NA NA 17748 XM_044328702.1 16 22 37 12 63 NA NA NA NA NA NA 17749 XM_044318694.1 185 223 283 271 682 Q7Z494 4.84e-51 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 17750 XM_044318694.1 185 223 283 271 682 Q7Z494 2.07e-50 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 17751 XM_044318694.1 185 223 283 271 682 Q7Z494 6.76e-45 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 17752 XM_044318694.1 185 223 283 271 682 Q7Z494 2.35e-44 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 17753 XR_006394559.1 37 5 47 29 9 NA NA NA NA NA NA 17754 XM_044313505.1 0 0 0 74 0 Q9D051 0 Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (PDHE1-B) (EC 1.2.4.1) Mus musculus (Mouse) acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; tricarboxylic acid cycle [GO:0006099] GO:0004739; GO:0005654; GO:0005739; GO:0005967; GO:0006006; GO:0006086; GO:0006099; GO:0034604; GO:0045240; GO:0045254; GO:1902493; GO:1902494 17755 XM_029325273.2 7071 8675 3465 6337 5768 G1T1F0 1.72e-74 NA NA NA NA 17756 XM_029347701.2 291 242 258 236 315 Q569B7 7.15e-53 RWD domain-containing protein 4 Rattus norvegicus (Rat) NA NA 17757 XM_044314113.1 2 19 0 0 6 NA NA NA NA NA NA 17758 XM_044322585.1 22 0 5 0 55 NA NA NA NA NA NA 17759 XM_044323654.1 15 4 12 2 4 NA NA NA NA NA NA 17760 XM_044317901.1 89 31 41 82 188 NA NA NA NA NA NA 17761 XM_044308593.1 9 0 0 3 2 NA NA NA NA NA NA 17762 XM_029336660.2 1 0 18 0 23 NA NA NA NA NA NA 17763 XM_044306850.1 0 58 25 0 46 NA NA NA NA NA NA 17764 XM_029333015.2 2598 2894 1656 2726 2234 Q90384 6.38e-101 Peroxiredoxin (EC 1.11.1.24) (Animal blastomere protein, 25 kDa) (ABP-25) (Thioredoxin peroxidase) (Thioredoxin-dependent peroxide reductase) (Thioredoxin-dependent peroxiredoxin) Cynops pyrrhogaster (Japanese fire-bellied newt) (Molge pyrrhogaster) NA GO:0140824 17765 XM_029348411.2 2436 2595 2135 2363 2746 Q99KW9 1.54e-96 T-cell immunomodulatory protein (Protein TIP) (Integrin-alpha FG-GAP repeat-containing protein 1) (Linkin) Mus musculus (Mouse) NA GO:0005576; GO:0005886 17766 XM_029349130.2 349 82 210 318 205 Q6NRC9 0 Leucine-rich repeat and coiled-coil domain-containing protein 1 Xenopus laevis (African clawed frog) cell cycle [GO:0007049]; cell division [GO:0051301] GO:0005737; GO:0005814; GO:0007049; GO:0051301 17767 XM_029338855.2 65 27 25 15 47 Q8VBT2 1.81e-75 L-serine dehydratase/L-threonine deaminase (SDH) (EC 4.3.1.17) (L-serine deaminase) (L-threonine dehydratase) (TDH) (EC 4.3.1.19) Mus musculus (Mouse) gluconeogenesis [GO:0006094]; isoleucine biosynthetic process [GO:0009097]; L-serine catabolic process [GO:0006565]; lipid metabolic process [GO:0006629]; protein-containing complex assembly [GO:0065003]; pyruvate biosynthetic process [GO:0042866]; threonine catabolic process [GO:0006567] GO:0003941; GO:0004794; GO:0005739; GO:0005829; GO:0006094; GO:0006565; GO:0006567; GO:0006629; GO:0009097; GO:0030170; GO:0042803; GO:0042866; GO:0065003 17768 XM_029327074.2 2114 2409 1703 1586 1113 Q9Y5U9 8.82e-27 Immediate early response 3-interacting protein 1 Homo sapiens (Human) brain development [GO:0007420]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; organ growth [GO:0035265]; positive regulation of extracellular matrix constituent secretion [GO:0003331]; positive regulation of protein secretion [GO:0050714]; protein transport [GO:0015031]; regulation of fibroblast apoptotic process [GO:2000269] GO:0000139; GO:0003331; GO:0005783; GO:0005789; GO:0005794; GO:0006888; GO:0007420; GO:0015031; GO:0016020; GO:0030134; GO:0035265; GO:0050714; GO:2000269 17769 XM_044328061.1 452 338 272 425 612 O97902 0 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein) (ADP-ribosylation factor-directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (DEF-1) (Differentiation-enhancing factor 1) (PIP2-dependent ARF1 GAP) Bos taurus (Bovine) cilium assembly [GO:0060271]; positive regulation of GTPase activity [GO:0043547]; positive regulation of membrane tubulation [GO:1903527] GO:0002102; GO:0005096; GO:0005737; GO:0016020; GO:0043547; GO:0046872; GO:0060271; GO:1903527 17770 XM_029328905.2 0 0 0 11 0 Q0R4F1 0 ATP-dependent DNA helicase PIF1 (EC 3.6.4.12) (DNA repair and recombination helicase PIF1) Xenopus laevis (African clawed frog) DNA recombination [GO:0006310]; DNA repair [GO:0006281]; mitochondrial genome maintenance [GO:0000002]; telomere maintenance [GO:0000723] GO:0000002; GO:0000723; GO:0003677; GO:0005524; GO:0005634; GO:0005739; GO:0006281; GO:0006310; GO:0016887; GO:0043139 17771 XM_029345067.2 348 177 169 228 343 Q9QXM0 1.13e-89 Monoacylglycerol lipase ABHD2 (EC 3.1.1.23) (2-arachidonoylglycerol hydrolase) (Abhydrolase domain-containing protein 2) (Acetylesterase) (EC 3.1.1.6) (Lung alpha/beta hydrolase 2) (MmLABH2) (Triacylglycerol lipase) (EC 3.1.1.79) Mus musculus (Mouse) acrosome reaction [GO:0007340]; acylglycerol catabolic process [GO:0046464]; cellular lipid metabolic process [GO:0044255]; medium-chain fatty acid biosynthetic process [GO:0051792]; medium-chain fatty acid catabolic process [GO:0051793]; negative regulation of smooth muscle cell migration [GO:0014912]; response to progesterone [GO:0032570]; response to wounding [GO:0009611]; smooth muscle cell migration [GO:0014909]; sperm capacitation [GO:0048240]; steroid hormone mediated signaling pathway [GO:0043401] GO:0001669; GO:0002080; GO:0003707; GO:0004806; GO:0007340; GO:0008126; GO:0009611; GO:0014909; GO:0014912; GO:0032570; GO:0033878; GO:0034338; GO:0036126; GO:0042562; GO:0043401; GO:0044255; GO:0046464; GO:0047372; GO:0048240; GO:0051792; GO:0051793; GO:0097524 17772 XM_044313371.1 273 176 132 262 449 Q93YS4 8.71e-71 ABC transporter G family member 22 (ABC transporter ABCG.22) (AtABCG22) (White-brown complex homolog protein 23) (AtWBC23) Arabidopsis thaliana (Mouse-ear cress) response to water deprivation [GO:0009414]; transmembrane transport [GO:0055085]; transpiration [GO:0010148] GO:0005524; GO:0009414; GO:0010148; GO:0016020; GO:0016887; GO:0042626; GO:0055085; GO:0140359 17773 XM_044313371.1 273 176 132 262 449 Q93YS4 6.15e-42 ABC transporter G family member 22 (ABC transporter ABCG.22) (AtABCG22) (White-brown complex homolog protein 23) (AtWBC23) Arabidopsis thaliana (Mouse-ear cress) response to water deprivation [GO:0009414]; transmembrane transport [GO:0055085]; transpiration [GO:0010148] GO:0005524; GO:0009414; GO:0010148; GO:0016020; GO:0016887; GO:0042626; GO:0055085; GO:0140359 17774 XM_029333924.2 303 15 256 257 182 Q4R979 3.16e-21 RNA-binding protein 4 (RNA-binding motif protein 4) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) cap-independent translational initiation [GO:0002190]; circadian regulation of gene expression [GO:0032922]; circadian regulation of translation [GO:0097167]; enteroendocrine cell differentiation [GO:0035883]; entrainment of circadian clock by photoperiod [GO:0043153]; insulin secretion involved in cellular response to glucose stimulus [GO:0035773]; IRES-dependent translational initiation of linear mRNA [GO:0002192]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; mRNA processing [GO:0006397]; negative regulation of translation [GO:0017148]; negative regulation of translation in response to stress [GO:0032055]; negative regulation of translational initiation [GO:0045947]; pancreas development [GO:0031016]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of translation [GO:0045727]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of nucleocytoplasmic transport [GO:0046822]; response to arsenic-containing substance [GO:0046685]; RNA splicing [GO:0008380] GO:0000381; GO:0002190; GO:0002192; GO:0003723; GO:0003729; GO:0003730; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0006397; GO:0008270; GO:0008380; GO:0010494; GO:0016607; GO:0017148; GO:0030332; GO:0031016; GO:0032055; GO:0032922; GO:0035198; GO:0035278; GO:0035773; GO:0035883; GO:0036002; GO:0043153; GO:0045727; GO:0045947; GO:0046626; GO:0046685; GO:0046822; GO:0048471; GO:0051149; GO:0097157; GO:0097158; GO:0097167 17775 XM_044316259.1 2 0 6 0 0 NA NA NA NA NA NA 17776 XR_006392950.1 41 2 25 5 151 NA NA NA NA NA NA 17777 XM_029334732.2 0 4 0 0 114 NA NA NA NA NA NA 17778 XM_029328878.2 173 88 110 136 141 NA NA NA NA NA NA 17779 XM_044320291.1 311 197 168 173 313 NA NA NA NA NA NA 17780 XM_029356272.2 1001 568 661 1037 722 NA NA NA NA NA NA 17781 XM_044307756.1 410 392 288 535 358 Q3MIT2 8.79e-113 tRNA pseudouridine synthase Pus10 (Hup10) (EC 5.4.99.25) (Coiled-coil domain-containing protein 139) (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA pseudouridylate synthase) (tRNA-uridine isomerase) Homo sapiens (Human) primary miRNA processing [GO:0031053]; tRNA pseudouridine synthesis [GO:0031119] GO:0005634; GO:0005737; GO:0005739; GO:0009982; GO:0031053; GO:0031119; GO:0046872; GO:0070878; GO:0106029 17782 XM_044321469.1 317 96 60 188 154 A0A1D3PCM3 1.32e-135 Serine O-succinyltransferase (SST) (EC 2.3.1.-) Emericella nidulans (Aspergillus nidulans) cysteine biosynthetic process [GO:0019344] GO:0005739; GO:0016747; GO:0019344 17783 XM_044315243.1 37 142 38 32 114 NA NA NA NA NA NA 17784 XM_029324097.2 13 0 0 35 0 NA NA NA NA NA NA 17785 XM_029356178.2 39 60 64 43 98 Q6PIJ6 5.27e-109 F-box only protein 38 Homo sapiens (Human) adaptive immune response [GO:0002250]; positive regulation of neuron projection development [GO:0010976]; positive regulation of T cell mediated immune response to tumor cell [GO:0002842]; protein K48-linked ubiquitination [GO:0070936]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0002250; GO:0002842; GO:0005634; GO:0005737; GO:0005829; GO:0010976; GO:0019005; GO:0031146; GO:0070936 17786 XM_029356178.2 39 60 64 43 98 Q6PIJ6 5.87e-31 F-box only protein 38 Homo sapiens (Human) adaptive immune response [GO:0002250]; positive regulation of neuron projection development [GO:0010976]; positive regulation of T cell mediated immune response to tumor cell [GO:0002842]; protein K48-linked ubiquitination [GO:0070936]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0002250; GO:0002842; GO:0005634; GO:0005737; GO:0005829; GO:0010976; GO:0019005; GO:0031146; GO:0070936 17787 XM_044323997.1 350 212 180 1023 1008 NA NA NA NA NA NA 17788 XM_044308076.1 6 14 12 11 27 NA NA NA NA NA NA 17789 XM_029355573.2 318 208 237 356 561 Q6Y1H2 7.43e-83 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 (EC 4.2.1.134) (3-hydroxyacyl-CoA dehydratase 2) (HACD2) (Protein-tyrosine phosphatase-like member B) Homo sapiens (Human) fatty acid elongation [GO:0030497]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; sphingolipid biosynthetic process [GO:0030148]; very long-chain fatty acid biosynthetic process [GO:0042761] GO:0005783; GO:0005789; GO:0018812; GO:0019899; GO:0030148; GO:0030497; GO:0035338; GO:0042761; GO:0080023; GO:0102158; GO:0102343; GO:0102344; GO:0102345 17790 XM_029358148.2 243 212 0 330 328 NA NA NA NA NA NA 17791 XM_029327591.2 3975 2143 1547 2216 1280 Q5U4C9 0 Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1) Mus musculus (Mouse) intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of glycogen biosynthetic process [GO:0045725]; protein phosphorylation [GO:0006468]; smoothened signaling pathway [GO:0007224] GO:0000151; GO:0000287; GO:0004674; GO:0004712; GO:0004713; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0006468; GO:0007224; GO:0018105; GO:0018107; GO:0018108; GO:0030145; GO:0042771; GO:0045725; GO:0070885; GO:0106310; GO:1990904 17792 XM_044311112.1 0 9 7 0 6 NA NA NA NA NA NA 17793 XR_003825158.2 62 22 6 26 40 NA NA NA NA NA NA 17794 XM_029338700.2 18 24 0 56 61 NA NA NA NA NA NA 17795 XR_003822867.2 103 0 7 10 0 NA NA NA NA NA NA 17796 XM_044325713.1 899 1499 785 1317 1146 Q9R283 8.58e-30 Short transient receptor potential channel 2 (TrpC2) (Transient receptor protein 2) (TRP-2) (rTrp2) Rattus norvegicus (Rat) acrosome reaction [GO:0007340]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; female courtship behavior [GO:0008050]; inter-male aggressive behavior [GO:0002121]; mating behavior, sex discrimination [GO:0048047]; negative regulation of male mating behavior [GO:1902436]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to pheromone [GO:0019236]; single fertilization [GO:0007338]; single strand break repair [GO:0000012]; territorial aggressive behavior [GO:0002124] GO:0000012; GO:0000139; GO:0002121; GO:0002124; GO:0003684; GO:0005635; GO:0005789; GO:0005886; GO:0006816; GO:0007204; GO:0007338; GO:0007340; GO:0008050; GO:0010468; GO:0012505; GO:0015279; GO:0019236; GO:0019992; GO:0032590; GO:0034703; GO:0048047; GO:0051480; GO:0070588; GO:0070679; GO:1902436 17797 XR_003824509.2 0 0 0 0 251 NA NA NA NA NA NA 17798 XM_029338661.2 187 161 297 160 181 P56434 7.09e-39 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6 (EC 2.4.1.152) (Fucosyltransferase 6) (Fucosyltransferase VI) (Fuc-TVI) (FucT-VI) (Galactoside 3-L-fucosyltransferase) Pan troglodytes (Chimpanzee) fucosylation [GO:0036065]; glycosphingolipid biosynthetic process [GO:0006688]; N-glycan fucosylation [GO:0036071]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493] GO:0005576; GO:0005794; GO:0006487; GO:0006493; GO:0006688; GO:0017083; GO:0032580; GO:0036065; GO:0036071; GO:0046920 17799 XM_029327562.2 4 1 0 30 0 NA NA NA NA NA NA 17800 XM_044311287.1 33 19 61 107 66 B8V7S0 1.18e-58 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 17801 XR_006397477.1 0 102 110 74 85 NA NA NA NA NA NA 17802 XM_029349996.2 13 6 6 1 39 NA NA NA NA NA NA 17803 XM_029345931.2 194 23 6 31 65 Q95JD5 6.35e-54 Sulfotransferase 1B1 (ST1B1) (cSULT1B1) (EC 2.8.2.1) (Sulfotransferase family cytosolic 1B member 1) Canis lupus familiaris (Dog) (Canis familiaris) 3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; epithelial cell differentiation [GO:0030855]; ethanol catabolic process [GO:0006068]; flavonoid metabolic process [GO:0009812]; sulfation [GO:0051923]; thyroid hormone metabolic process [GO:0042403]; xenobiotic metabolic process [GO:0006805] GO:0004062; GO:0005737; GO:0006068; GO:0006805; GO:0008146; GO:0009812; GO:0030855; GO:0042403; GO:0050427; GO:0051923 17804 XM_044314606.1 107 55 14 47 19 NA NA NA NA NA NA 17805 XR_006394877.1 115 3 66 145 97 NA NA NA NA NA NA 17806 XM_044314613.1 2 6 3 0 6 NA NA NA NA NA NA 17807 XM_044320332.1 51 21 47 173 49 NA NA NA NA NA NA 17808 XR_006392416.1 0 6 3 8 1 NA NA NA NA NA NA 17809 XM_044306801.1 459 1121 220 360 433 E0W1I1 1.76e-73 Serine/threonine-protein kinase Pink1, mitochondrial (EC 2.7.11.1) (PTEN-induced putative kinase 1) Pediculus humanus subsp. corporis (Body louse) autophagy [GO:0006914]; protein phosphorylation [GO:0006468] GO:0004672; GO:0004674; GO:0005524; GO:0005741; GO:0005743; GO:0005829; GO:0006468; GO:0006914; GO:0046872 17810 XM_044310912.1 0 0 22 1 0 NA NA NA NA NA NA 17811 XM_029329909.2 129 45 7 201 49 B8VIU6 6.65e-92 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 17812 XM_029323438.2 473 486 190 349 351 P30520 0 Adenylosuccinate synthetase isozyme 2 (AMPSase 2) (AdSS 2) (EC 6.3.4.4) (Adenylosuccinate synthetase, acidic isozyme) (Adenylosuccinate synthetase, liver isozyme) (L-type adenylosuccinate synthetase) (IMP--aspartate ligase 2) Homo sapiens (Human) 'de novo' AMP biosynthetic process [GO:0044208]; AMP biosynthetic process [GO:0006167]; aspartate metabolic process [GO:0006531]; cellular response to electrical stimulus [GO:0071257]; immune system process [GO:0002376]; IMP metabolic process [GO:0046040]; response to ammonium ion [GO:0060359]; response to purine-containing compound [GO:0014074] GO:0000287; GO:0002376; GO:0004019; GO:0005525; GO:0005737; GO:0005739; GO:0005829; GO:0006167; GO:0006531; GO:0014074; GO:0042301; GO:0044208; GO:0046040; GO:0060359; GO:0070062; GO:0071257 17813 XM_029330207.2 0 78 88 159 0 Q9TU19 9.57e-121 Nephrocystin-1 Canis lupus familiaris (Dog) (Canis familiaris) cell differentiation [GO:0030154]; cell projection organization [GO:0030030]; protein localization involved in establishment of planar polarity [GO:0090251]; spermatogenesis [GO:0007283] GO:0005737; GO:0005856; GO:0005911; GO:0005912; GO:0005923; GO:0005929; GO:0007283; GO:0030030; GO:0030154; GO:0090251 17814 XM_044328709.1 23 74 49 9 23 Q9BX70 1.53e-73 BTB/POZ domain-containing protein 2 Homo sapiens (Human) neurogenesis [GO:0022008] GO:0000932; GO:0005829; GO:0022008 17815 XM_029355747.2 201 65 127 173 236 P24507 9.91e-39 Synaptotagmin-C (Synaptic vesicle protein O-p65-C) Diplobatis ommata (Ocellated electric ray) (Discopyge ommata) NA GO:0030672; GO:0046872 17816 XM_029355886.2 64 18 107 22 252 NA NA NA NA NA NA 17817 XM_044310269.1 322 153 93 113 178 NA NA NA NA NA NA 17818 XM_029338920.2 198 103 85 137 227 NA NA NA NA NA NA 17819 XR_006391477.1 0 14 0 3 0 NA NA NA NA NA NA 17820 XM_044328043.1 0 0 8 0 5 NA NA NA NA NA NA 17821 XM_044318458.1 0 18 6 6 21 NA NA NA NA NA NA 17822 XM_029333613.2 337 504 460 367 411 Q9D903 2.21e-50 Probable rRNA-processing protein EBP2 Mus musculus (Mouse) ribosomal large subunit biogenesis [GO:0042273]; rRNA processing [GO:0006364] GO:0005694; GO:0005730; GO:0006364; GO:0030687; GO:0034399; GO:0042273 17823 XM_029328881.2 1059 516 687 923 1672 Q0P5N6 7.26e-45 ADP-ribosylation factor-like protein 16 Homo sapiens (Human) NA GO:0003924; GO:0005525; GO:0005737 17824 XM_044328502.1 23 8 34 42 48 NA NA NA NA NA NA 17825 XM_044324555.1 3 0 1 5 55 NA NA NA NA NA NA 17826 XM_044322009.1 14623 10326 6211 13662 5571 Q01196 2.02e-80 Runt-related transcription factor 1 (Acute myeloid leukemia 1 protein) (Core-binding factor subunit alpha-2) (CBF-alpha-2) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEA2-alpha B) (PEBP2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit) Homo sapiens (Human) cardiac muscle tissue regeneration [GO:0061026]; chondrocyte differentiation [GO:0002062]; hematopoietic stem cell proliferation [GO:0071425]; hemopoiesis [GO:0030097]; myeloid cell differentiation [GO:0030099]; myeloid leukocyte differentiation [GO:0002573]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron differentiation [GO:0030182]; ossification [GO:0001503]; peripheral nervous system neuron development [GO:0048935]; positive regulation of angiogenesis [GO:0045766]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extracellular matrix organization [GO:1903055]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of cell differentiation [GO:0045595]; regulation of connective tissue replacement [GO:1905203]; regulation of plasminogen activation [GO:0010755]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000785; GO:0000976; GO:0000977; GO:0000978; GO:0000981; GO:0001222; GO:0001223; GO:0001228; GO:0001503; GO:0002062; GO:0002573; GO:0003677; GO:0003700; GO:0005509; GO:0005524; GO:0005634; GO:0005654; GO:0006357; GO:0010755; GO:0016513; GO:0030097; GO:0030099; GO:0030182; GO:0030853; GO:0030854; GO:0032743; GO:0032967; GO:0042803; GO:0043231; GO:0043371; GO:0043378; GO:0045595; GO:0045766; GO:0045893; GO:0045944; GO:0046982; GO:0048935; GO:0060043; GO:0061026; GO:0071425; GO:0140297; GO:1903055; GO:1905203 17827 XM_044311160.1 49 15 67 28 73 NA NA NA NA NA NA 17828 XM_044323698.1 11 17 40 5 6 NA NA NA NA NA NA 17829 XM_029324218.2 2361 3094 2216 2312 1407 Q5R628 5.43e-47 U6 snRNA-associated Sm-like protein LSm5 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0003723; GO:0005634; GO:0046540; GO:0071005; GO:0120115 17830 XM_029354607.2 1338 1017 976 2293 1846 NA NA NA NA NA NA 17831 XM_044324382.1 113 16 24 0 0 NA NA NA NA NA NA 17832 XM_044319691.1 257 255 448 343 252 E7FAM5 2.29e-78 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 17833 XM_044321320.1 5 0 0 2 46 Q7TN88 5.51e-73 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 17834 XM_044321320.1 5 0 0 2 46 Q7TN88 1.12e-51 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 17835 XM_044328448.1 6 1 0 4 4 NA NA NA NA NA NA 17836 XM_044323630.1 0 0 0 68 72 NA NA NA NA NA NA 17837 XM_029346064.2 720 500 266 604 108 NA NA NA NA NA NA 17838 XM_044318642.1 0 3 0 7 0 Q7TNH6 1.99e-44 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 17839 XM_044318642.1 0 3 0 7 0 Q7TNH6 1.83e-43 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 17840 XM_044318642.1 0 3 0 7 0 Q7TNH6 4.7e-38 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 17841 XM_044308968.1 0 0 11 4 22 NA NA NA NA NA NA 17842 XR_006392775.1 7 21 19 9 26 NA NA NA NA NA NA 17843 XM_029355293.2 1908 1627 1778 1719 1989 O43741 1.35e-57 5'-AMP-activated protein kinase subunit beta-2 (AMPK subunit beta-2) Homo sapiens (Human) cellular response to nutrient levels [GO:0031669]; fatty acid biosynthetic process [GO:0006633]; positive regulation of cold-induced thermogenesis [GO:0120162]; signal transduction [GO:0007165] GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006633; GO:0007165; GO:0019901; GO:0031588; GO:0031669; GO:0120162 17844 XM_044309262.1 3955 2628 2286 5552 3570 NA NA NA NA NA NA 17845 XM_029337511.2 2516 586 1641 1775 716 Q6P963 8.81e-111 Hydroxyacylglutathione hydrolase, mitochondrial (EC 3.1.2.6) (Glyoxalase II) (Glx II) Danio rerio (Zebrafish) (Brachydanio rerio) glutathione metabolic process [GO:0006749]; methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243] GO:0004416; GO:0005739; GO:0005759; GO:0006749; GO:0019243; GO:0046872 17846 XM_044324936.1 93 27 20 7 53 P35409 1.87e-135 Probable glycoprotein hormone G-protein coupled receptor Anthopleura elegantissima (Green aggregating anemone) (Actinia elegantissima) NA GO:0004930; GO:0005886; GO:0016500 17847 XM_044324936.1 93 27 20 7 53 P35409 3.79e-32 Probable glycoprotein hormone G-protein coupled receptor Anthopleura elegantissima (Green aggregating anemone) (Actinia elegantissima) NA GO:0004930; GO:0005886; GO:0016500 17848 XR_003827939.2 35 0 51 0 0 NA NA NA NA NA NA 17849 XM_044325846.1 0 13 2 0 3 NA NA NA NA NA NA 17850 XM_044325539.1 0 1 18 0 68 Q3UQI9 1.17e-131 Probable ubiquitin carboxyl-terminal hydrolase MINDY-4 (EC 3.4.19.12) (Probable deubiquitinating enzyme MINDY-4) Mus musculus (Mouse) protein K48-linked deubiquitination [GO:0071108] GO:0004843; GO:0071108; GO:1990380 17851 XM_029337376.2 228 188 185 261 220 Q5BJQ5 1.75e-40 GTP-binding protein Rit2 (EC 3.6.5.2) Rattus norvegicus (Rat) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; intracellular signal transduction [GO:0035556]; maintenance of protein location in cell [GO:0032507]; negative regulation of neuron projection development [GO:0010977]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron projection development [GO:0010976]; positive regulation of transcription by RNA polymerase II [GO:0045944]; Ras protein signal transduction [GO:0007265]; regulation of calcium-mediated signaling [GO:0050848]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of endocytosis [GO:0030100]; regulation of protein phosphorylation [GO:0001932] GO:0001932; GO:0003682; GO:0003924; GO:0003925; GO:0005516; GO:0005525; GO:0005634; GO:0005654; GO:0005737; GO:0005794; GO:0005829; GO:0005886; GO:0007189; GO:0007265; GO:0010976; GO:0010977; GO:0019003; GO:0030100; GO:0030215; GO:0032489; GO:0032507; GO:0035556; GO:0043005; GO:0043410; GO:0044297; GO:0045121; GO:0045944; GO:0050848; GO:0097447 17852 XR_003825484.2 186 131 137 150 183 NA NA NA NA NA NA 17853 XM_029354963.2 391 278 338 337 121 NA NA NA NA NA NA 17854 XM_029354161.2 16 10 78 55 57 NA NA NA NA NA NA 17855 XR_006396971.1 4 39 32 27 0 NA NA NA NA NA NA 17856 XR_006398067.1 152 66 116 190 201 NA NA NA NA NA NA 17857 XM_044311463.1 0 86 0 0 0 Q3SZN3 2.03e-36 Metalloendopeptidase OMA1, mitochondrial (EC 3.4.24.-) (Overlapping with the m-AAA protease 1 homolog) Bos taurus (Bovine) diet induced thermogenesis [GO:0002024]; energy homeostasis [GO:0097009]; glucose metabolic process [GO:0006006]; HRI-mediated signaling [GO:0140468]; integrated stress response signaling [GO:0140467]; lipid metabolic process [GO:0006629]; mitochondrial protein processing [GO:0034982]; mitochondrial respiratory chain complex assembly [GO:0033108]; negative regulation of mitochondrial fusion [GO:0010637]; positive regulation of apoptotic process [GO:0043065]; protein autoprocessing [GO:0016540]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of cristae formation [GO:1903850]; zymogen activation [GO:0031638] GO:0002024; GO:0004222; GO:0005743; GO:0006006; GO:0006515; GO:0006629; GO:0008289; GO:0010637; GO:0016020; GO:0016540; GO:0031638; GO:0031966; GO:0033108; GO:0034982; GO:0043065; GO:0046872; GO:0051603; GO:0097009; GO:0140467; GO:0140468; GO:1903850 17858 XM_044311463.1 0 86 0 0 0 Q3SZN3 2.03e-36 Metalloendopeptidase OMA1, mitochondrial (EC 3.4.24.-) (Overlapping with the m-AAA protease 1 homolog) Bos taurus (Bovine) diet induced thermogenesis [GO:0002024]; energy homeostasis [GO:0097009]; glucose metabolic process [GO:0006006]; HRI-mediated signaling [GO:0140468]; integrated stress response signaling [GO:0140467]; lipid metabolic process [GO:0006629]; mitochondrial protein processing [GO:0034982]; mitochondrial respiratory chain complex assembly [GO:0033108]; negative regulation of mitochondrial fusion [GO:0010637]; positive regulation of apoptotic process [GO:0043065]; protein autoprocessing [GO:0016540]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of cristae formation [GO:1903850]; zymogen activation [GO:0031638] GO:0002024; GO:0004222; GO:0005743; GO:0006006; GO:0006515; GO:0006629; GO:0008289; GO:0010637; GO:0016020; GO:0016540; GO:0031638; GO:0031966; GO:0033108; GO:0034982; GO:0043065; GO:0046872; GO:0051603; GO:0097009; GO:0140467; GO:0140468; GO:1903850 17859 XM_029351626.2 369 694 423 640 630 NA NA NA NA NA NA 17860 XM_029356573.2 110 9 27 81 27 NA NA NA NA NA NA 17861 XM_029350048.2 1199 839 529 505 243 NA NA NA NA NA NA 17862 XM_029358229.2 52 16 12 48 39 P15388 4.29e-98 Potassium voltage-gated channel subfamily C member 1 (NGK2) (Voltage-gated potassium channel subunit Kv3.1) (Voltage-gated potassium channel subunit Kv4) Mus musculus (Mouse) cellular response to xenobiotic stimulus [GO:0071466]; cerebellum development [GO:0021549]; corpus callosum development [GO:0022038]; globus pallidus development [GO:0021759]; optic nerve development [GO:0021554]; positive regulation of ion transmembrane transport [GO:0034767]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of voltage-gated potassium channel activity [GO:1903818]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; protein tetramerization [GO:0051262]; regulation of ion transmembrane transport [GO:0034765]; regulation of potassium ion transmembrane transport [GO:1901379]; response to amine [GO:0014075]; response to auditory stimulus [GO:0010996]; response to fibroblast growth factor [GO:0071774]; response to light intensity [GO:0009642]; response to nerve growth factor [GO:1990089]; response to potassium ion [GO:0035864]; response to toxic substance [GO:0009636] GO:0005249; GO:0005251; GO:0008076; GO:0009636; GO:0009642; GO:0009986; GO:0010996; GO:0014075; GO:0016020; GO:0019894; GO:0021549; GO:0021554; GO:0021759; GO:0022038; GO:0030424; GO:0030425; GO:0030673; GO:0032589; GO:0032590; GO:0032809; GO:0034765; GO:0034767; GO:0035864; GO:0042734; GO:0043025; GO:0044305; GO:0044325; GO:0045211; GO:0051260; GO:0051262; GO:0071466; GO:0071774; GO:0071805; GO:0099508; GO:1901379; GO:1901381; GO:1903818; GO:1990089 17863 XM_029350756.2 0 21 0 31 52 P51029 5.8e-71 Protein Wnt-8b Danio rerio (Zebrafish) (Brachydanio rerio) canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; commissural neuron axon guidance [GO:0071679]; embryonic pattern specification [GO:0009880]; eye development [GO:0001654]; eye field cell fate commitment involved in camera-type eye formation [GO:0060898]; forebrain development [GO:0030900]; forebrain neuron differentiation [GO:0021879]; hypothalamus development [GO:0021854]; negative regulation of anterior neural cell fate commitment of the neural plate by Wnt signaling pathway [GO:0022002]; neuron differentiation [GO:0030182]; otic placode formation [GO:0043049]; sensory epithelium regeneration [GO:0070654] GO:0001654; GO:0005109; GO:0005125; GO:0005615; GO:0009880; GO:0021854; GO:0021879; GO:0022002; GO:0030182; GO:0030900; GO:0043049; GO:0045165; GO:0060070; GO:0060898; GO:0070654; GO:0071679 17864 XR_006393500.1 321 157 49 312 482 NA NA NA NA NA NA 17865 XM_029355348.2 298 169 167 227 316 NA NA NA NA NA NA 17866 XM_029346961.2 56 47 36 40 105 P84239 6.54e-92 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 17867 XM_029338283.2 71 10 53 24 20 Q9FL28 3.93e-26 LRR receptor-like serine/threonine-protein kinase FLS2 (EC 2.7.11.1) (Protein FLAGELLIN-SENSING 2) (Protein FLAGELLIN-SENSITIVE 2) Arabidopsis thaliana (Mouse-ear cress) defense response by callose deposition in cell wall [GO:0052544]; defense response to bacterium [GO:0042742]; detection of bacterium [GO:0016045]; protein phosphorylation [GO:0006468]; receptor-mediated endocytosis [GO:0006898]; regulation of anion channel activity [GO:0010359] GO:0004675; GO:0005524; GO:0005768; GO:0005886; GO:0006468; GO:0006898; GO:0010008; GO:0010359; GO:0012505; GO:0016020; GO:0016045; GO:0042742; GO:0042802; GO:0052544; GO:0106310 17868 XM_029355763.2 0 1 6 0 18 NA NA NA NA NA NA 17869 XR_006395523.1 912 898 428 375 193 NA NA NA NA NA NA 17870 XM_029327066.2 117 0 58 0 0 Q7TN31 4.76e-60 Angiogenic factor with G patch and FHA domains 1 (Angiogenic factor VG5Q) (mVG5Q) Mus musculus (Mouse) angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; positive regulation of angiogenesis [GO:0045766]; positive regulation of endothelial cell proliferation [GO:0001938] GO:0001525; GO:0001938; GO:0003676; GO:0005576; GO:0005737; GO:0007155; GO:0030154; GO:0045766; GO:0048471 17871 XM_029356880.2 10 41 16 55 2 NA NA NA NA NA NA 17872 XM_044314446.1 394 267 213 236 348 Q5RED7 8.32e-79 Acylglycerol kinase, mitochondrial (EC 2.7.1.107) (EC 2.7.1.138) (EC 2.7.1.94) (Multiple substrate lipid kinase) (MuLK) (Multi-substrate lipid kinase) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) ceramide biosynthetic process [GO:0046513]; glycerolipid metabolic process [GO:0046486]; protein insertion into mitochondrial inner membrane [GO:0045039] GO:0001729; GO:0004143; GO:0005524; GO:0005743; GO:0005758; GO:0031966; GO:0042721; GO:0045039; GO:0046486; GO:0046513; GO:0047620; GO:0102773 17873 XM_044318190.1 0 2 7 27 0 NA NA NA NA NA NA 17874 XM_029358593.2 1337 1124 676 1131 1055 Q5R4A0 0 NEDD8-activating enzyme E1 catalytic subunit (EC 6.2.1.64) (NEDD8-activating enzyme E1C) (Ubiquitin-activating enzyme E1C) (Ubiquitin-like modifier-activating enzyme 3) (Ubiquitin-activating enzyme 3) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) endomitotic cell cycle [GO:0007113]; protein neddylation [GO:0045116]; regulation of cell cycle [GO:0051726] GO:0005524; GO:0005634; GO:0007113; GO:0019781; GO:0032991; GO:0042802; GO:0045116; GO:0046982; GO:0051726 17875 XM_029340765.2 0 0 0 40 0 NA NA NA NA NA NA 17876 XM_029358515.2 2156 1725 1301 3726 3628 NA NA NA NA NA NA 17877 XM_029349773.2 1106 2437 1879 25 0 NA NA NA NA NA NA 17878 XM_029331423.2 1813 1428 827 1088 1034 O43447 2.16e-98 Peptidyl-prolyl cis-trans isomerase H (PPIase H) (EC 5.2.1.8) (Rotamase H) (Small nuclear ribonucleoprotein particle-specific cyclophilin H) (CypH) (U-snRNP-associated cyclophilin SnuCyp-20) (USA-CYP) Homo sapiens (Human) mRNA splicing, via spliceosome [GO:0000398]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein-containing complex assembly [GO:0065003] GO:0000398; GO:0000413; GO:0003755; GO:0005654; GO:0005681; GO:0005737; GO:0005829; GO:0006457; GO:0016018; GO:0016607; GO:0043021; GO:0043231; GO:0045070; GO:0046540; GO:0065003; GO:0071001 17879 XM_029348015.2 991 835 771 1704 1053 Q76KP1 3.11e-61 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Homo sapiens (Human) NA GO:0008376; GO:0032580; GO:0033842 17880 XM_029348015.2 991 835 771 1704 1053 Q76KP1 2.18e-25 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Homo sapiens (Human) NA GO:0008376; GO:0032580; GO:0033842 17881 XM_044323421.1 72 1850 72 857 568 NA NA NA NA NA NA 17882 XM_029357773.2 25 14 10 11 24 P18841 1.35e-28 Alpha-1B adrenergic receptor (Alpha-1B adrenoreceptor) (Alpha-1B adrenoceptor) Mesocricetus auratus (Golden hamster) positive regulation of MAPK cascade [GO:0043410]; regulation of cardiac muscle contraction [GO:0055117]; regulation of vasoconstriction [GO:0019229] GO:0004937; GO:0005634; GO:0005737; GO:0005886; GO:0005901; GO:0019229; GO:0031965; GO:0043410; GO:0046982; GO:0055117 17883 XM_044307777.1 304 222 116 315 209 NA NA NA NA NA NA 17884 XM_029353458.2 0 9 0 0 0 NA NA NA NA NA NA 17885 XM_029326828.2 395 321 246 337 647 NA NA NA NA NA NA 17886 XM_029341091.2 3269 3538 1620 1920 2124 Q969Q5 1.2e-76 Ras-related protein Rab-24 Homo sapiens (Human) autophagy [GO:0006914]; intracellular protein transport [GO:0006886] GO:0003924; GO:0005525; GO:0005768; GO:0005776; GO:0005829; GO:0005886; GO:0006886; GO:0006914; GO:0012505; GO:0030139; GO:0030667 17887 XM_044309924.1 27 3 49 30 494 P14381 5.29e-46 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 17888 XM_044311268.1 0 0 0 0 6 P34456 1.51e-23 Uncharacterized protein F54H12.2 Caenorhabditis elegans deoxyribonucleotide biosynthetic process [GO:0009263] GO:0004748; GO:0005829; GO:0009263 17889 XM_044318820.1 2094 18 2464 6008 3519 Q8IVV2 7.49e-102 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 17890 XM_044318820.1 2094 18 2464 6008 3519 Q8IVV2 1.16e-99 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 17891 XM_044318820.1 2094 18 2464 6008 3519 Q8IVV2 1.97e-98 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 17892 XM_044318820.1 2094 18 2464 6008 3519 Q8IVV2 1.11e-95 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 17893 XM_044318820.1 2094 18 2464 6008 3519 Q8IVV2 4.71e-88 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 17894 XM_044318820.1 2094 18 2464 6008 3519 Q8IVV2 2.42e-82 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 17895 XM_044318820.1 2094 18 2464 6008 3519 Q8IVV2 3.93e-80 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 17896 XM_044318820.1 2094 18 2464 6008 3519 Q8IVV2 5.22e-73 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 17897 XM_029354483.2 135 82 142 161 173 Q5I597 4.35e-127 Betaine--homocysteine S-methyltransferase 1 (EC 2.1.1.5) Bos taurus (Bovine) amino-acid betaine catabolic process [GO:0006579]; L-methionine salvage [GO:0071267]; methionine biosynthetic process [GO:0009086]; methylation [GO:0032259] GO:0005634; GO:0005829; GO:0006579; GO:0008270; GO:0009086; GO:0032259; GO:0047150; GO:0071267 17898 XM_044324274.1 20 11 7 8 16 NA NA NA NA NA NA 17899 XR_006393224.1 156 16 71 84 70 Q21565 3.82e-89 Putative ammonium transporter 3 Caenorhabditis elegans ammonium homeostasis [GO:0097272]; ammonium transmembrane transport [GO:0072488] GO:0005886; GO:0008519; GO:0072488; GO:0097272 17900 XR_006393224.1 156 16 71 84 70 Q21565 3.82e-89 Putative ammonium transporter 3 Caenorhabditis elegans ammonium homeostasis [GO:0097272]; ammonium transmembrane transport [GO:0072488] GO:0005886; GO:0008519; GO:0072488; GO:0097272 17901 XM_044322167.1 436 201 192 260 204 Q80W54 0 CAAX prenyl protease 1 homolog (EC 3.4.24.84) (Farnesylated proteins-converting enzyme 1) (FACE-1) (Prenyl protein-specific endoprotease 1) (Zinc metalloproteinase Ste24 homolog) Mus musculus (Mouse) adult walking behavior [GO:0007628]; bone mineralization [GO:0030282]; CAAX-box protein processing [GO:0071586]; calcium ion import into sarcoplasmic reticulum [GO:1990036]; CAMKK-AMPK signaling cascade [GO:0061762]; cardiac conduction [GO:0061337]; cardiac muscle cell development [GO:0055013]; cardiac ventricle development [GO:0003231]; cellular lipid metabolic process [GO:0044255]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; chromatin organization [GO:0006325]; chromosome organization [GO:0051276]; determination of adult lifespan [GO:0008340]; DNA repair [GO:0006281]; epidermis development [GO:0008544]; growth plate cartilage development [GO:0003417]; hair follicle development [GO:0001942]; heart morphogenesis [GO:0003007]; histone H2B acetylation [GO:0043969]; histone H2B-K5 acetylation [GO:0043979]; hypomethylation of CpG island [GO:0044029]; inflammatory cell apoptotic process [GO:0006925]; kidney morphogenesis [GO:0060993]; liver development [GO:0001889]; maintenance of rDNA [GO:0043007]; multicellular organism growth [GO:0035264]; negative regulation of gene expression [GO:0010629]; negative regulation of miRNA maturation [GO:1903799]; neuromuscular process [GO:0050905]; nuclear envelope organization [GO:0006998]; nucleus organization [GO:0006997]; positive regulation of gene expression [GO:0010628]; prenylated protein catabolic process [GO:0030327]; protein processing [GO:0016485]; regulation of autophagy [GO:0010506]; regulation of blood circulation [GO:1903522]; regulation of bone mineralization [GO:0030500]; regulation of cell shape [GO:0008360]; regulation of cellular senescence [GO:2000772]; regulation of defense response to virus [GO:0050688]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of DNA methylation [GO:0044030]; regulation of DNA-templated transcription [GO:0006355]; regulation of fibroblast proliferation [GO:0048145]; regulation of glucose metabolic process [GO:0010906]; regulation of heart contraction [GO:0008016]; regulation of histone H4 acetylation [GO:0090239]; regulation of histone H4-K16 acetylation [GO:2000618]; regulation of hormone metabolic process [GO:0032350]; regulation of lipid metabolic process [GO:0019216]; regulation of mitotic cell cycle [GO:0007346]; regulation of mitotic cell cycle DNA replication [GO:1903463]; regulation of multicellular organism growth [GO:0040014]; regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903025]; regulation of stress-activated protein kinase signaling cascade [GO:0070302]; regulation of termination of RNA polymerase I transcription [GO:2000730]; regulation of TOR signaling [GO:0032006]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; response to DNA damage checkpoint signaling [GO:0072423]; thymus development [GO:0048538]; ventricular cardiac muscle tissue development [GO:0003229] GO:0001889; GO:0001942; GO:0003007; GO:0003229; GO:0003231; GO:0003417; GO:0003690; GO:0004175; GO:0004222; GO:0005635; GO:0005637; GO:0005789; GO:0006281; GO:0006325; GO:0006355; GO:0006925; GO:0006974; GO:0006997; GO:0006998; GO:0007346; GO:0007628; GO:0008016; GO:0008340; GO:0008360; GO:0008544; GO:0010506; GO:0010628; GO:0010629; GO:0010906; GO:0016020; GO:0016485; GO:0019216; GO:0030282; GO:0030327; GO:0030500; GO:0032006; GO:0032350; GO:0032991; GO:0035264; GO:0040014; GO:0043007; GO:0043516; GO:0043969; GO:0043979; GO:0044029; GO:0044030; GO:0044255; GO:0046872; GO:0048145; GO:0048538; GO:0050688; GO:0050905; GO:0051276; GO:0055013; GO:0060307; GO:0060993; GO:0061337; GO:0061762; GO:0070302; GO:0071480; GO:0071586; GO:0072423; GO:0090239; GO:1903025; GO:1903463; GO:1903522; GO:1903799; GO:1990036; GO:2000618; GO:2000730; GO:2000772 17902 XM_044328871.1 1618 843 537 1010 1360 Q8VHK2 4.99e-81 Caskin-1 (CASK-interacting protein 1) Rattus norvegicus (Rat) signal transduction [GO:0007165] GO:0005737; GO:0007165; GO:0016020; GO:0019904; GO:0042802 17903 XM_044328871.1 1618 843 537 1010 1360 Q8VHK2 2.66e-23 Caskin-1 (CASK-interacting protein 1) Rattus norvegicus (Rat) signal transduction [GO:0007165] GO:0005737; GO:0007165; GO:0016020; GO:0019904; GO:0042802 17904 XM_044316675.1 73 12 45 176 0 Q8R3B7 1.14e-57 Bromodomain-containing protein 8 Mus musculus (Mouse) cellular response to thyroid hormone stimulus [GO:0097067]; chromatin organization [GO:0006325]; histone acetylation [GO:0016573]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of double-strand break repair [GO:2000779] GO:0000786; GO:0000812; GO:0005654; GO:0005739; GO:0006325; GO:0016573; GO:0030374; GO:0035267; GO:0042981; GO:0043967; GO:0043968; GO:0045893; GO:0045944; GO:0046966; GO:0051726; GO:0097067; GO:1905168; GO:2000779 17905 XM_044316675.1 73 12 45 176 0 Q8R3B7 1.36e-38 Bromodomain-containing protein 8 Mus musculus (Mouse) cellular response to thyroid hormone stimulus [GO:0097067]; chromatin organization [GO:0006325]; histone acetylation [GO:0016573]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of double-strand break repair [GO:2000779] GO:0000786; GO:0000812; GO:0005654; GO:0005739; GO:0006325; GO:0016573; GO:0030374; GO:0035267; GO:0042981; GO:0043967; GO:0043968; GO:0045893; GO:0045944; GO:0046966; GO:0051726; GO:0097067; GO:1905168; GO:2000779 17906 XM_044322458.1 0 5 9 0 83 Q96AY4 2.49e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17907 XM_044322458.1 0 5 9 0 83 Q96AY4 2.69e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17908 XM_044322458.1 0 5 9 0 83 Q96AY4 1.7e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17909 XM_044322458.1 0 5 9 0 83 Q96AY4 2.61e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17910 XM_044322458.1 0 5 9 0 83 Q96AY4 7.28e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17911 XM_044322458.1 0 5 9 0 83 Q96AY4 5.12e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17912 XM_044322458.1 0 5 9 0 83 Q96AY4 2.07e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17913 XM_044322458.1 0 5 9 0 83 Q96AY4 2.66e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17914 XM_044322458.1 0 5 9 0 83 Q96AY4 5.26e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17915 XM_044322458.1 0 5 9 0 83 Q96AY4 2.62e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17916 XM_044322458.1 0 5 9 0 83 Q96AY4 9.42e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17917 XM_044313833.1 7 6 15 10 5 NA NA NA NA NA NA 17918 XM_044315673.1 9 26 0 9 0 Q94K49 2.02e-22 Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1 (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) epigenetic regulation of gene expression [GO:0040029] GO:0003682; GO:0004518; GO:0005634; GO:0035098; GO:0035102; GO:0040029; GO:0046872 17919 XM_029332564.2 338 585 538 202 441 Q8WXW3 0 Progesterone-induced-blocking factor 1 (PIBF) (Centrosomal protein of 90 kDa) (CEP90) Homo sapiens (Human) activation of Janus kinase activity [GO:0042976]; cilium assembly [GO:0060271]; immune system process [GO:0002376]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly [GO:0090307]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of natural killer cell activation [GO:0032815]; negative regulation of prostaglandin biosynthetic process [GO:0031393]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; non-motile cilium assembly [GO:1905515]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein localization to centrosome [GO:0071539] GO:0002376; GO:0005136; GO:0005615; GO:0005634; GO:0005737; GO:0005813; GO:0007080; GO:0031393; GO:0032695; GO:0032733; GO:0032815; GO:0034451; GO:0042531; GO:0042532; GO:0042976; GO:0060271; GO:0071539; GO:0090307; GO:1905515 17920 XM_029343090.2 148 143 322 69 130 E1BKH1 0 EF-hand domain-containing protein 1 (Myoclonin-1) Bos taurus (Bovine) cerebral cortex cell migration [GO:0021795]; cilium-dependent cell motility [GO:0060285]; mitotic cytokinesis [GO:0000281]; mitotic spindle organization [GO:0007052]; regulation of cell division [GO:0051302] GO:0000281; GO:0000922; GO:0005509; GO:0005813; GO:0005879; GO:0005930; GO:0007052; GO:0021795; GO:0043014; GO:0051302; GO:0060285; GO:0072686 17921 XM_029337887.2 74 14 20 58 64 NA NA NA NA NA NA 17922 XM_044323332.1 77 10 81 107 131 Q9H9B1 5.52e-147 Histone-lysine N-methyltransferase EHMT1 (EC 2.1.1.-) (EC 2.1.1.367) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a-like protein 1) (GLP) (GLP1) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Lysine N-methyltransferase 1D) Homo sapiens (Human) chromatin organization [GO:0006325]; DNA methylation [GO:0006306]; facultative heterochromatin formation [GO:0140718]; histone H3-K9 methylation [GO:0051567]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-lysine dimethylation [GO:0018027]; peptidyl-lysine monomethylation [GO:0018026]; positive regulation of cold-induced thermogenesis [GO:0120162]; regulation of embryonic development [GO:0045995]; regulation of histone H3-K9 methylation [GO:0051570] GO:0000122; GO:0000785; GO:0001222; GO:0002039; GO:0005634; GO:0005654; GO:0006306; GO:0006325; GO:0008168; GO:0008270; GO:0016279; GO:0016604; GO:0018024; GO:0018026; GO:0018027; GO:0045892; GO:0045995; GO:0046974; GO:0046976; GO:0051567; GO:0051570; GO:0070742; GO:0120162; GO:0140718; GO:0140947 17923 XM_044314035.1 1 0 0 0 7 NA NA NA NA NA NA 17924 XM_044328915.1 1313 759 750 1127 1210 A6NCI4 0 von Willebrand factor A domain-containing protein 3A Homo sapiens (Human) NA GO:0005576 17925 XM_044315149.1 17 12 20 13 55 NA NA NA NA NA NA 17926 XM_044310216.1 24 0 2 0 94 Q9Y2J2 7.11e-24 Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (Erythrocyte membrane protein band 4.1-like 3) [Cleaved into: Band 4.1-like protein 3, N-terminally processed] Homo sapiens (Human) actomyosin structure organization [GO:0031032]; apoptotic process [GO:0006915]; cortical actin cytoskeleton organization [GO:0030866]; cortical cytoskeleton organization [GO:0030865]; myelin maintenance [GO:0043217]; neuron projection morphogenesis [GO:0048812]; paranodal junction assembly [GO:0030913]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; protein localization to plasma membrane [GO:0072659]; regulation of cell shape [GO:0008360] GO:0002175; GO:0003779; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0005911; GO:0006915; GO:0008360; GO:0030054; GO:0030865; GO:0030866; GO:0030913; GO:0031032; GO:0033270; GO:0043217; GO:0044224; GO:0048812; GO:0071205; GO:0072659; GO:0106006 17927 XM_044310216.1 24 0 2 0 94 Q9Y2J2 7.11e-24 Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (Erythrocyte membrane protein band 4.1-like 3) [Cleaved into: Band 4.1-like protein 3, N-terminally processed] Homo sapiens (Human) actomyosin structure organization [GO:0031032]; apoptotic process [GO:0006915]; cortical actin cytoskeleton organization [GO:0030866]; cortical cytoskeleton organization [GO:0030865]; myelin maintenance [GO:0043217]; neuron projection morphogenesis [GO:0048812]; paranodal junction assembly [GO:0030913]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; protein localization to plasma membrane [GO:0072659]; regulation of cell shape [GO:0008360] GO:0002175; GO:0003779; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0005911; GO:0006915; GO:0008360; GO:0030054; GO:0030865; GO:0030866; GO:0030913; GO:0031032; GO:0033270; GO:0043217; GO:0044224; GO:0048812; GO:0071205; GO:0072659; GO:0106006 17928 XM_029332384.2 0 0 0 176 0 P78357 1.08e-59 Contactin-associated protein 1 (Caspr) (Caspr1) (Neurexin IV) (Neurexin-4) (p190) Homo sapiens (Human) axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cytoskeleton organization [GO:0007010]; mitochondrion organization [GO:0007005]; myelination in peripheral nervous system [GO:0022011]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; neuron projection morphogenesis [GO:0048812]; neuronal action potential propagation [GO:0019227]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; postsynaptic density organization [GO:0097106]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; regulation of synapse maturation [GO:0090128]; signal transduction [GO:0007165] GO:0002175; GO:0005886; GO:0007005; GO:0007010; GO:0007155; GO:0007165; GO:0007409; GO:0016020; GO:0017124; GO:0019227; GO:0022010; GO:0022011; GO:0030913; GO:0033010; GO:0033270; GO:0038023; GO:0048786; GO:0048812; GO:0050884; GO:0050885; GO:0071205; GO:0090128; GO:0097106; GO:0098529; GO:0098978; GO:1990227 17929 XM_044311127.1 49 78 189 75 164 NA NA NA NA NA NA 17930 XM_029324250.2 852 654 503 789 997 Q5ZKK5 7.39e-158 Outer dense fiber protein 2 (Cenexin) (Outer dense fiber of sperm tails protein 2) Gallus gallus (Chicken) cell differentiation [GO:0030154]; regulation of cilium assembly [GO:1902017]; spermatogenesis [GO:0007283] GO:0000922; GO:0005737; GO:0005813; GO:0005814; GO:0005874; GO:0007283; GO:0030154; GO:0036126; GO:1902017 17931 XM_029358228.2 38 74 33 145 125 NA NA NA NA NA NA 17932 XM_044325949.1 955 759 626 818 640 NA NA NA NA NA NA 17933 XR_006397088.1 151 127 56 56 104 NA NA NA NA NA NA 17934 XR_006394650.1 27 0 7 25 32 NA NA NA NA NA NA 17935 XR_003823160.2 1 3 6 0 28 NA NA NA NA NA NA 17936 XM_044314041.1 15 50 60 23 135 NA NA NA NA NA NA 17937 XM_044327881.1 17 9 33 26 34 P08953 1.05e-60 Protein toll Drosophila melanogaster (Fruit fly) antifungal innate immune response [GO:0061760]; cell adhesion [GO:0007155]; cell competition in a multicellular organism [GO:0035212]; defense response to Gram-positive bacterium [GO:0050830]; defense response to oomycetes [GO:0002229]; detection of virus [GO:0009597]; dorsal/ventral axis specification [GO:0009950]; heart development [GO:0007507]; innate immune response [GO:0045087]; larval somatic muscle development [GO:0007526]; negative regulation of cell growth [GO:0030308]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of multicellular organism growth [GO:0040015]; positive regulation of antifungal peptide production [GO:0002804]; positive regulation of antimicrobial peptide production [GO:0002225]; positive regulation of hemocyte proliferation [GO:0035208]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of embryonic pattern specification [GO:1902875]; response to tumor cell [GO:0002347]; response to wounding [GO:0009611]; synapse assembly [GO:0007416]; synaptic target inhibition [GO:0016201]; Toll signaling pathway [GO:0008063]; toll-like receptor signaling pathway [GO:0002224] GO:0002224; GO:0002225; GO:0002229; GO:0002347; GO:0002804; GO:0004888; GO:0004896; GO:0005769; GO:0005886; GO:0007155; GO:0007416; GO:0007507; GO:0007526; GO:0008063; GO:0009597; GO:0009611; GO:0009897; GO:0009950; GO:0009986; GO:0016201; GO:0019955; GO:0030308; GO:0032154; GO:0035208; GO:0035212; GO:0038023; GO:0040015; GO:0042802; GO:0045087; GO:0045944; GO:0046627; GO:0046790; GO:0050135; GO:0050830; GO:0061760; GO:0061809; GO:0070976; GO:1902875 17938 XR_003828486.2 2 4 4 5 7 NA NA NA NA NA NA 17939 XM_044315180.1 676 649 533 1303 318 NA NA NA NA NA NA 17940 XM_044321065.1 957 1232 648 651 293 P28304 5.68e-62 Quinone oxidoreductase 1 (EC 1.6.5.5) (NADPH:quinone reductase 1) (Zeta-crystallin homolog protein) Escherichia coli (strain K12) NA GO:0003960; GO:0005829; GO:0008270; GO:0016651; GO:0070402 17941 XM_044328260.1 3831 2578 2082 3350 3063 P18484 0 AP-2 complex subunit alpha-2 (100 kDa coated vesicle protein C) (Adaptor protein complex AP-2 subunit alpha-2) (Adaptor-related protein complex 2 subunit alpha-2) (Alpha-adaptin C) (Alpha2-adaptin) (Clathrin assembly protein complex 2 alpha-C large chain) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit) Rattus norvegicus (Rat) clathrin-dependent endocytosis [GO:0072583]; intracellular protein transport [GO:0006886] GO:0005886; GO:0006886; GO:0008021; GO:0019900; GO:0019901; GO:0019904; GO:0030117; GO:0030122; GO:0031410; GO:0035091; GO:0035615; GO:0044877; GO:0072583; GO:0097718; GO:0120283; GO:0140312 17942 XM_029339309.2 204 18 0 41 10 NA NA NA NA NA NA 17943 XM_029352128.2 2534 3095 1739 2877 1841 Q6DHR8 1.93e-51 Dehydrodolichyl diphosphate synthase complex subunit nus1 (EC 2.5.1.87) (Di-trans,poly-cis-decaprenylcistransferase) (Nogo-B receptor) (NgBR) (Nuclear undecaprenyl pyrophosphate synthase 1 homolog) Danio rerio (Zebrafish) (Brachydanio rerio) dolichol biosynthetic process [GO:0019408]; protein glycosylation [GO:0006486]; sprouting angiogenesis [GO:0002040] GO:0002040; GO:0005789; GO:0006486; GO:0016765; GO:0019408; GO:1904423 17944 XM_029331029.2 120 19 25 51 13 NA NA NA NA NA NA 17945 XR_003824491.2 1777 1830 1111 1913 2082 NA NA NA NA NA NA 17946 XM_044310323.1 13 0 1 0 35 NA NA NA NA NA NA 17947 XM_044323351.1 6 1 1 29 30 NA NA NA NA NA NA 17948 XM_044328736.1 0 21 10 6 0 Q96AY4 2.2e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17949 XM_044328736.1 0 21 10 6 0 Q96AY4 2.54e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17950 XM_044328736.1 0 21 10 6 0 Q96AY4 4.65e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17951 XM_044328736.1 0 21 10 6 0 Q96AY4 5.9e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17952 XM_044328736.1 0 21 10 6 0 Q96AY4 1.38e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17953 XM_044328736.1 0 21 10 6 0 Q96AY4 7.83e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17954 XM_029334740.2 6 13 6 13 8 Q5M8E6 3.56e-117 tRNA N(3)-methylcytidine methyltransferase METTL2 (EC 2.1.1.-) (Methyltransferase-like protein 2) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) tRNA methylation [GO:0030488] GO:0005737; GO:0016427; GO:0030488 17955 XM_044315915.1 0 0 0 2 6 NA NA NA NA NA NA 17956 XM_044326594.1 0 1 9 0 2 NA NA NA NA NA NA 17957 XR_003824896.2 368 177 110 281 303 NA NA NA NA NA NA 17958 XM_044307500.1 14 10 17 5 34 NA NA NA NA NA NA 17959 XR_006392914.1 41 2 25 5 151 NA NA NA NA NA NA 17960 XR_006396269.1 256 132 156 141 416 NA NA NA NA NA NA 17961 XM_029346983.2 95 36 15 17 5 NA NA NA NA NA NA 17962 XM_044317295.1 653 386 137 255 0 Q155U0 0 Vacuolar protein sorting-associated protein 51 homolog (Protein fat-free) Danio rerio (Zebrafish) (Brachydanio rerio) endocytic recycling [GO:0032456]; Golgi organization [GO:0007030]; Golgi vesicle transport [GO:0048193]; lipid digestion [GO:0044241]; lipid transport [GO:0006869]; lysosomal transport [GO:0007041]; protein transport [GO:0015031]; regulation of phospholipase activity [GO:0010517]; retrograde transport, endosome to Golgi [GO:0042147] GO:0000938; GO:0005829; GO:0006869; GO:0007030; GO:0007041; GO:0010517; GO:0015031; GO:0016020; GO:0031267; GO:0032456; GO:0042147; GO:0044241; GO:0048193; GO:0055037; GO:1990745 17963 XM_044329330.1 189 198 274 286 534 Q7TN88 2.86e-73 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 17964 XM_044329330.1 189 198 274 286 534 Q7TN88 8.23e-51 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 17965 XM_029333131.2 5 10 22 2 36 Q3B8D7 2.37e-22 Dynein light chain Tctex-type 5-A (Tctex1 domain-containing protein 1-A) Xenopus laevis (African clawed frog) NA NA 17966 XM_029336969.2 347 151 112 232 355 O23300 3.83e-21 Enoyl-CoA delta isomerase 3 (EC 5.3.3.8) (3-hydroxyacyl-CoA dehydratase 1) (Delta(3),Delta(2)-enoyl CoA isomerase 3) (AtECI3) Arabidopsis thaliana (Mouse-ear cress) fatty acid beta-oxidation [GO:0006635]; fatty acid catabolic process [GO:0009062] GO:0004165; GO:0005634; GO:0005829; GO:0006635; GO:0009062 17967 XM_029341247.2 409 303 131 349 207 Q8JI28 4.35e-33 Tolloid-like protein 1 (EC 3.4.24.-) (Metalloprotease xolloid-like) (Xenopus tolloid-like protein 1) (Xlr) Xenopus laevis (African clawed frog) cell differentiation [GO:0030154]; proteolysis [GO:0006508] GO:0004222; GO:0005509; GO:0005576; GO:0006508; GO:0008270; GO:0030154 17968 XM_029341247.2 409 303 131 349 207 Q8JI28 3.26e-26 Tolloid-like protein 1 (EC 3.4.24.-) (Metalloprotease xolloid-like) (Xenopus tolloid-like protein 1) (Xlr) Xenopus laevis (African clawed frog) cell differentiation [GO:0030154]; proteolysis [GO:0006508] GO:0004222; GO:0005509; GO:0005576; GO:0006508; GO:0008270; GO:0030154 17969 XR_003827432.2 30 1 17 13 111 NA NA NA NA NA NA 17970 XM_044325625.1 7 0 0 0 72 Q9HAR2 9.78e-59 Adhesion G protein-coupled receptor L3 (Calcium-independent alpha-latrotoxin receptor 3) (CIRL-3) (Latrophilin-3) (Lectomedin-3) Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; brain development [GO:0007420]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; G protein-coupled receptor signaling pathway [GO:0007186]; neuron migration [GO:0001764]; synapse assembly [GO:0007416] GO:0001764; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007166; GO:0007186; GO:0007189; GO:0007416; GO:0007420; GO:0016020; GO:0030246; GO:0030424; GO:0098742; GO:0098978 17971 XM_029351601.2 357 544 98 1735 1839 P07700 1.08e-22 Beta-1 adrenergic receptor (Beta-1 adrenoreceptor) (Beta-1 adrenoceptor) (Beta-T) Meleagris gallopavo (Wild turkey) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; positive regulation of GTPase activity [GO:0043547]; positive regulation of heart contraction [GO:0045823]; regulation of circadian sleep/wake cycle, sleep [GO:0045187] GO:0004940; GO:0005085; GO:0005769; GO:0005886; GO:0016020; GO:0042802; GO:0043547; GO:0045187; GO:0045823; GO:0071880 17972 XM_044323605.1 0 0 0 13 17 NA NA NA NA NA NA 17973 XM_029341614.2 2568 2428 1810 2965 2352 Q5PRF9 1.55e-73 Protein Smaug homolog 2 (Smaug 2) (hSmaug2) (Sterile alpha motif domain-containing protein 4B) (SAM domain-containing protein 4B) Homo sapiens (Human) nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289] GO:0000289; GO:0000932; GO:0003723; GO:0003729; GO:0005634; GO:0005829; GO:0030371 17974 XR_006396214.1 47 13 18 38 0 NA NA NA NA NA NA 17975 XM_029337875.2 6880 7443 3168 7699 3607 P78417 1.61e-51 Glutathione S-transferase omega-1 (GSTO-1) (EC 2.5.1.18) (Glutathione S-transferase omega 1-1) (GSTO 1-1) (Glutathione-dependent dehydroascorbate reductase) (EC 1.8.5.1) (Monomethylarsonic acid reductase) (MMA(V) reductase) (EC 1.20.4.2) (S-(Phenacyl)glutathione reductase) (SPG-R) Homo sapiens (Human) cellular response to arsenic-containing substance [GO:0071243]; glutathione metabolic process [GO:0006749]; L-ascorbic acid metabolic process [GO:0019852]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014810]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; xenobiotic catabolic process [GO:0042178] GO:0004364; GO:0005737; GO:0005829; GO:0006749; GO:0010880; GO:0010881; GO:0014810; GO:0016491; GO:0019852; GO:0042178; GO:0045174; GO:0050610; GO:0060315; GO:0060316; GO:0070062; GO:0071243 17976 XM_029337216.2 896 547 321 557 728 Q8IV35 2.68e-99 WD repeat-containing protein 49 Homo sapiens (Human) NA NA 17977 XR_006395455.1 195 20 123 43 932 NA NA NA NA NA NA 17978 XR_006393018.1 142 0 166 143 21 NA NA NA NA NA NA 17979 XM_029336605.2 95 0 0 195 304 Q641E3 1.12e-24 Acyl-CoA-binding domain-containing protein 5 Xenopus laevis (African clawed frog) autophagy of peroxisome [GO:0030242] GO:0000062; GO:0005778; GO:0030242 17980 XM_044325480.1 99 60 171 423 420 NA NA NA NA NA NA 17981 XM_044322569.1 0 0 0 359 525 P49916 0 DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3) Homo sapiens (Human) base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cell cycle [GO:0007049]; cell division [GO:0051301]; DNA biosynthetic process [GO:0071897]; DNA ligation [GO:0006266]; double-strand break repair [GO:0006302]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; double-strand break repair via homologous recombination [GO:0000724]; lagging strand elongation [GO:0006273]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of mitochondrial DNA replication [GO:0090298] GO:0000724; GO:0003677; GO:0003909; GO:0003910; GO:0005524; GO:0005634; GO:0005654; GO:0005739; GO:0006266; GO:0006273; GO:0006287; GO:0006288; GO:0006302; GO:0007005; GO:0007049; GO:0008270; GO:0043504; GO:0051301; GO:0070421; GO:0071897; GO:0090298; GO:0097681 17982 XM_044324225.1 172 41 49 119 175 Q9VBW3 8.61e-82 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 17983 XR_003824802.2 43 91 131 117 163 NA NA NA NA NA NA 17984 XM_044310786.1 7 5 9 39 202 NA NA NA NA NA NA 17985 XM_044317815.1 155 54 110 48 40 Q11126 4.24e-41 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3 (EC 2.4.1.65) (4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase) (EC 2.4.1.152) (Alpha-3-fucosyltransferase FUT3) (EC 2.4.1.-) (Blood group Lewis alpha-4-fucosyltransferase) (Lewis FT) (FUTB) (Fucosyltransferase 3) (Fucosyltransferase III) (FucT-III) Bos taurus (Bovine) fucosylation [GO:0036065]; lipid metabolic process [GO:0006629]; oligosaccharide metabolic process [GO:0009311]; positive regulation of cell-cell adhesion [GO:0022409]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127] GO:0006487; GO:0006493; GO:0006629; GO:0009311; GO:0017060; GO:0017083; GO:0022409; GO:0030334; GO:0032580; GO:0036065; GO:0042127; GO:0046920 17986 XM_029329617.2 1099 754 662 827 823 B5KFL3 7.26e-50 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 (EC 5.2.1.8) (Parvulin-14) (Par14) (Peptidyl-prolyl cis-trans isomerase Pin4) (PPIase Pin4) (Rotamase Pin4) Taeniopygia guttata (Zebra finch) (Poephila guttata) rRNA processing [GO:0006364] GO:0003677; GO:0003755; GO:0005730; GO:0005737; GO:0005819; GO:0006364 17987 XM_029357471.2 96 161 174 447 576 B0BNE2 3.52e-117 DNA-directed RNA polymerases I, II, and III subunit RPABC1 (RNA polymerases I, II, and III subunit ABC1) (DNA-directed RNA polymerase II subunit E) (RPB5 homolog) Rattus norvegicus (Rat) transcription by RNA polymerase II [GO:0006366] GO:0003677; GO:0003899; GO:0005634; GO:0005665; GO:0005666; GO:0005736; GO:0006366; GO:1990062 17988 XM_029330684.2 438 497 307 393 365 P0C7T6 8.68e-31 Ataxin-1-like (Brother of ataxin-1) Mus musculus (Mouse) anatomical structure development [GO:0048856]; brain development [GO:0007420]; extracellular matrix organization [GO:0030198]; learning [GO:0007612]; lung alveolus development [GO:0048286]; memory [GO:0007613]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; regulation of DNA-templated transcription [GO:0006355]; social behavior [GO:0035176]; transcription by RNA polymerase II [GO:0006366] GO:0000122; GO:0003677; GO:0003723; GO:0005634; GO:0005654; GO:0005730; GO:0006355; GO:0006366; GO:0007420; GO:0007612; GO:0007613; GO:0030198; GO:0030425; GO:0035176; GO:0048286; GO:0048856; GO:1902035 17989 XM_044327572.1 80 123 62 91 125 Q8NEV4 0 Myosin-IIIa (EC 2.7.11.1) Homo sapiens (Human) cochlea morphogenesis [GO:0090103]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of filopodium assembly [GO:0051491]; protein autophosphorylation [GO:0046777]; regulation of actin filament length [GO:0030832]; response to stimulus [GO:0050896]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] GO:0000146; GO:0001917; GO:0003779; GO:0004672; GO:0004674; GO:0005516; GO:0005524; GO:0005737; GO:0007601; GO:0007605; GO:0016459; GO:0018105; GO:0030175; GO:0030832; GO:0031941; GO:0032426; GO:0032433; GO:0043531; GO:0046777; GO:0050896; GO:0051491; GO:0060002; GO:0090103; GO:0106310 17990 XM_044327276.1 21 4 0 0 0 NA NA NA NA NA NA 17991 XM_029357122.2 1935 904 825 1826 2071 Q5XH95 0 Calcium-binding mitochondrial carrier protein SCaMC-2 (Small calcium-binding mitochondrial carrier protein 2) (Solute carrier family 25 member 25) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) transmembrane transport [GO:0055085] GO:0005509; GO:0005743; GO:0055085 17992 XM_029356172.2 268 150 138 167 142 NA NA NA NA NA NA 17993 XM_029355777.2 536 381 303 674 373 Q8CJ69 1.09e-95 BMP-binding endothelial regulator protein (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2) Mus musculus (Mouse) blood vessel development [GO:0001568]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; BMP signaling pathway [GO:0030509]; common-partner SMAD protein phosphorylation [GO:0007182]; endothelial cell activation [GO:0042118]; inner ear development [GO:0048839]; negative regulation of BMP signaling pathway [GO:0030514]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of sprouting angiogenesis [GO:1903672]; regulation of angiogenesis [GO:0045765]; regulation of endothelial cell migration [GO:0010594]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization [GO:0032880]; ureteric bud development [GO:0001657] GO:0001568; GO:0001657; GO:0002043; GO:0005576; GO:0005615; GO:0007182; GO:0010594; GO:0030509; GO:0030514; GO:0031012; GO:0032880; GO:0042118; GO:0045765; GO:0048839; GO:0060393; GO:0062023; GO:0070374; GO:1903672 17994 XM_029340841.2 3868 2429 2193 4491 4991 Q8TE73 0 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5) Homo sapiens (Human) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0005524; GO:0005576; GO:0005737; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 17995 XR_006396473.1 6 86 0 100 55 NA NA NA NA NA NA 17996 XR_006395707.1 74 12 38 20 17 A1L1W9 9.46e-37 Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10) Danio rerio (Zebrafish) (Brachydanio rerio) aromatic amino acid transport [GO:0015801]; thyroid hormone transport [GO:0070327] GO:0005302; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0070327 17997 XM_029328318.2 47 51 56 93 3 NA NA NA NA NA NA 17998 XM_044306943.1 9 9 21 0 0 Q96PD2 2.05e-22 Discoidin, CUB and LCCL domain-containing protein 2 (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1) (Endothelial and smooth muscle cell-derived neuropilin-like protein) Homo sapiens (Human) intracellular receptor signaling pathway [GO:0030522]; negative regulation of cell growth [GO:0030308]; wound healing [GO:0042060] GO:0005886; GO:0009986; GO:0030308; GO:0030522; GO:0038023; GO:0042060 17999 XM_029351161.2 14 0 9 0 58 NA NA NA NA NA NA 18000 XM_044323433.1 3 19 52 37 74 NA NA NA NA NA NA 18001 XR_006392259.1 0 5 19 5 55 NA NA NA NA NA NA 18002 XM_029340254.2 0 31 21 0 0 NA NA NA NA NA NA 18003 XM_044311759.1 0 6 17 4 1 NA NA NA NA NA NA 18004 XM_029339058.2 0 0 27 35 20 Q13889 1.21e-103 General transcription factor IIH subunit 3 (Basic transcription factor 2 34 kDa subunit) (BTF2 p34) (General transcription factor IIH polypeptide 3) (TFIIH basal transcription factor complex p34 subunit) Homo sapiens (Human) DNA repair [GO:0006281]; nucleotide-excision repair [GO:0006289]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; transcription by RNA polymerase II [GO:0006366] GO:0000438; GO:0000439; GO:0005634; GO:0005654; GO:0005669; GO:0005675; GO:0006281; GO:0006289; GO:0006366; GO:0016251; GO:0046872; GO:0047485; GO:0070816; GO:0097550 18005 XR_006394398.1 31 0 0 0 27 NA NA NA NA NA NA 18006 XR_006395016.1 29 36 31 30 30 NA NA NA NA NA NA 18007 XR_003826422.2 0 0 0 11 0 NA NA NA NA NA NA 18008 XM_029343939.2 0 0 0 46 86 NA NA NA NA NA NA 18009 XM_029335999.2 286 155 60 345 362 O75762 4.14e-99 Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation-sensitive protein p120) (p120) (Wasabi receptor) Homo sapiens (Human) calcium ion transmembrane transport [GO:0070588]; cell surface receptor signaling pathway [GO:0007166]; cellular calcium ion homeostasis [GO:0006874]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to organic substance [GO:0071310]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; ion transport [GO:0006811]; protein homotetramerization [GO:0051289]; response to cold [GO:0009409]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; sensory perception of pain [GO:0019233]; thermoception [GO:0050955] GO:0005262; GO:0005886; GO:0006811; GO:0006874; GO:0007166; GO:0009409; GO:0009410; GO:0010033; GO:0014070; GO:0015267; GO:0015278; GO:0019233; GO:0032421; GO:0042802; GO:0048265; GO:0050955; GO:0050966; GO:0050968; GO:0051289; GO:0070301; GO:0070588; GO:0071310; GO:0097604 18010 XM_029333152.2 1154 977 536 1128 1146 Q5W8I8 2.18e-126 Vesicular glutamate transporter 2.1 (Protein blumenkohl) (Solute carrier family 17 member 6-B) (Vesicular glutamate transporter 2-A) Danio rerio (Zebrafish) (Brachydanio rerio) anion transport [GO:0006820]; chemical synaptic transmission [GO:0007268]; L-glutamate import [GO:0051938]; L-glutamate transmembrane transport [GO:0015813]; neurotransmitter loading into synaptic vesicle [GO:0098700]; phosphate ion homeostasis [GO:0055062]; phosphate ion transport [GO:0006817]; regulation of synapse structure or activity [GO:0050803]; response to stimulus [GO:0050896]; sodium-dependent phosphate transport [GO:0044341]; synaptic transmission, glutamatergic [GO:0035249]; visual perception [GO:0007601] GO:0005254; GO:0005313; GO:0005326; GO:0005436; GO:0005886; GO:0006817; GO:0006820; GO:0007268; GO:0007601; GO:0008021; GO:0015386; GO:0015813; GO:0016020; GO:0022857; GO:0030672; GO:0034707; GO:0035249; GO:0043005; GO:0044341; GO:0050803; GO:0050896; GO:0051938; GO:0055062; GO:0060076; GO:0098700; GO:0140788 18011 XM_029355054.2 1546 1989 944 1798 1863 P35486 3.03e-162 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial (EC 1.2.4.1) (PDHE1-A type I) Mus musculus (Mouse) acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; tricarboxylic acid cycle [GO:0006099] GO:0004738; GO:0004739; GO:0005730; GO:0005739; GO:0005967; GO:0006006; GO:0006086; GO:0006099; GO:0034604; GO:0043209; GO:0045254; GO:1902494 18012 XM_029344866.2 1065 6 52 976 837 D3ZTD8 1.28e-83 Semaphorin-5A (Semaphorin-F) (Sema F) Rattus norvegicus (Rat) axon extension [GO:0048675]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; cell chemotaxis [GO:0060326]; detection of light stimulus involved in visual perception [GO:0050908]; diencephalon development [GO:0021536]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of cell adhesion [GO:0007162]; negative regulation of endothelial cell apoptotic process [GO:2000352]; neural crest cell migration [GO:0001755]; neuron projection extension [GO:1990138]; neuron projection guidance [GO:0097485]; positive chemotaxis [GO:0050918]; positive regulation of actin filament depolymerization [GO:0030836]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein kinase B signaling [GO:0051897]; semaphorin-plexin signaling pathway [GO:0071526]; signal clustering [GO:1990256] GO:0001569; GO:0001755; GO:0001938; GO:0002043; GO:0007162; GO:0007411; GO:0007413; GO:0008046; GO:0016020; GO:0021536; GO:0030215; GO:0030335; GO:0030836; GO:0035373; GO:0043395; GO:0045499; GO:0045545; GO:0045766; GO:0048675; GO:0048754; GO:0048842; GO:0048843; GO:0050908; GO:0050918; GO:0051897; GO:0060326; GO:0071526; GO:0090263; GO:0097485; GO:1990138; GO:1990256; GO:2000352; GO:2001028 18013 XM_029343967.2 526 476 406 496 572 NA NA NA NA NA NA 18014 XM_044323987.1 0 0 100 44 48 NA NA NA NA NA NA 18015 XM_044315519.1 7 21 11 1 32 NA NA NA NA NA NA 18016 XM_029342077.2 2975 2216 2042 2370 2518 P20072 3.73e-118 Annexin A7 (Annexin VII) (Annexin-7) (Synexin) Bos taurus (Bovine) NA GO:0005509; GO:0005544; GO:0005634; GO:0005737; GO:0042584 18017 XM_044307102.1 22 0 8 16 0 Q58DM8 4.83e-128 Enoyl-CoA hydratase, mitochondrial (mECH) (mECH1) (EC 4.2.1.17) (EC 5.3.3.8) (Enoyl-CoA hydratase 1) (ECHS1) (Short-chain enoyl-CoA hydratase) (SCEH) Bos taurus (Bovine) fatty acid beta-oxidation [GO:0006635] GO:0004165; GO:0004300; GO:0005739; GO:0005759; GO:0006635; GO:0043956; GO:0120092 18018 XR_006395946.1 122 174 60 196 218 P09487 1.1e-144 Alkaline phosphatase, tissue-nonspecific isozyme (AP-TNAP) (TNAP) (TNSALP) (EC 3.1.3.1) (Alkaline phosphatase liver/bone/kidney isozyme) (Phosphoamidase) (Phosphocreatine phosphatase) (EC 3.9.1.1) Bos taurus (Bovine) biomineral tissue development [GO:0031214]; bone mineralization [GO:0030282]; calcium ion homeostasis [GO:0055074]; cellular homeostasis [GO:0019725]; cellular response to organic cyclic compound [GO:0071407]; dephosphorylation [GO:0016311]; developmental process involved in reproduction [GO:0003006]; endochondral ossification [GO:0001958]; multicellular organism aging [GO:0010259]; phosphate ion homeostasis [GO:0055062]; positive regulation of cold-induced thermogenesis [GO:0120162]; pyridoxal phosphate metabolic process [GO:0042822]; response to antibiotic [GO:0046677]; response to sodium phosphate [GO:1904383]; response to vitamin B6 [GO:0034516]; response to vitamin D [GO:0033280] GO:0001958; GO:0003006; GO:0004035; GO:0004427; GO:0005509; GO:0005758; GO:0005886; GO:0010259; GO:0016311; GO:0016462; GO:0016887; GO:0019725; GO:0030282; GO:0031012; GO:0031214; GO:0031966; GO:0033280; GO:0033883; GO:0034516; GO:0042822; GO:0043262; GO:0046677; GO:0050187; GO:0052732; GO:0055062; GO:0055074; GO:0065010; GO:0071407; GO:0120162; GO:1904383 18019 XM_044315604.1 0 0 11 6 7 P04323 5.9e-26 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 18020 XM_044323305.1 0 0 48 13 4 NA NA NA NA NA NA 18021 XR_003826735.2 0 49 6 7 45 NA NA NA NA NA NA 18022 XM_044325033.1 1 0 0 16 62 NA NA NA NA NA NA 18023 XM_029336281.2 23 45 20 25 48 Q9NSA2 1.63e-84 Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) Homo sapiens (Human) potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005250; GO:0005886; GO:0008076; GO:0014069; GO:0016020; GO:0034765; GO:0043025; GO:0043197; GO:0045211; GO:0046872; GO:0051260; GO:0071805 18024 XM_029323909.2 237 189 165 302 319 NA NA NA NA NA NA 18025 XR_003823818.2 7 244 0 291 228 NA NA NA NA NA NA 18026 XM_029338097.2 94 249 118 198 569 NA NA NA NA NA NA 18027 XR_006394940.1 200 305 37 114 49 NA NA NA NA NA NA 18028 XR_006396212.1 0 20 0 0 44 NA NA NA NA NA NA 18029 XM_044309909.1 1 30 1 0 73 NA NA NA NA NA NA 18030 XM_029327543.2 1766 1336 1051 1514 1414 Q14790 2.65e-48 Caspase-8 (CASP-8) (EC 3.4.22.61) (Apoptotic cysteine protease) (Apoptotic protease Mch-5) (CAP4) (FADD-homologous ICE/ced-3-like protease) (FADD-like ICE) (FLICE) (ICE-like apoptotic protease 5) (MORT1-associated ced-3 homolog) (MACH) [Cleaved into: Caspase-8 subunit p18; Caspase-8 subunit p10] Homo sapiens (Human) activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; B cell activation [GO:0042113]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; execution phase of apoptosis [GO:0097194]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; heart development [GO:0007507]; macrophage differentiation [GO:0030225]; natural killer cell activation [GO:0030101]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of necroptotic process [GO:0060546]; positive regulation of apoptotic process [GO:0043065]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of neuron death [GO:1901216]; positive regulation of proteolysis [GO:0045862]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; pyroptosis [GO:0070269]; regulation of cytokine production [GO:0001817]; regulation of innate immune response [GO:0045088]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to antibiotic [GO:0046677]; response to cobalt ion [GO:0032025]; response to cold [GO:0009409]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]; self proteolysis [GO:0097264]; syncytiotrophoblast cell differentiation involved in labyrinthine layer development [GO:0060715]; T cell activation [GO:0042110]; TRAIL-activated apoptotic signaling pathway [GO:0036462] GO:0001525; GO:0001817; GO:0004197; GO:0005123; GO:0005164; GO:0005654; GO:0005737; GO:0005739; GO:0005741; GO:0005829; GO:0005856; GO:0006508; GO:0006915; GO:0006919; GO:0007507; GO:0008233; GO:0008234; GO:0008303; GO:0008625; GO:0009409; GO:0010803; GO:0030101; GO:0030225; GO:0031264; GO:0031265; GO:0031625; GO:0032025; GO:0032355; GO:0032496; GO:0032731; GO:0032991; GO:0034612; GO:0035877; GO:0036462; GO:0042110; GO:0042113; GO:0042802; GO:0043005; GO:0043065; GO:0043123; GO:0043124; GO:0044297; GO:0044877; GO:0045088; GO:0045121; GO:0045471; GO:0045651; GO:0045862; GO:0046677; GO:0051603; GO:0060546; GO:0060715; GO:0070269; GO:0071260; GO:0071407; GO:0097110; GO:0097153; GO:0097190; GO:0097191; GO:0097194; GO:0097199; GO:0097200; GO:0097202; GO:0097264; GO:0097342; GO:1901216 18031 XM_044306790.1 0 0 0 0 15 NA NA NA NA NA NA 18032 XM_044321089.1 162 47 14 66 69 Q9NZJ4 0 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 18033 XM_029340878.2 2170 1668 1171 1481 1899 Q66IV6 3.77e-65 Charged multivesicular body protein 2b-B (Chromatin-modifying protein 2b-B) (CHMP2b-B) Xenopus laevis (African clawed frog) protein transport [GO:0015031]; vacuolar transport [GO:0007034] GO:0005829; GO:0007034; GO:0015031; GO:0031902 18034 XM_044319484.1 378 148 78 395 207 A0JM23 1.17e-49 Nephrocystin-3 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cilium assembly [GO:0060271]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; Wnt signaling pathway [GO:0016055] GO:0005929; GO:0016055; GO:0060271; GO:0090090; GO:2000095 18035 XM_044319484.1 378 148 78 395 207 A0JM23 1.16e-48 Nephrocystin-3 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cilium assembly [GO:0060271]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; Wnt signaling pathway [GO:0016055] GO:0005929; GO:0016055; GO:0060271; GO:0090090; GO:2000095 18036 XM_044319484.1 378 148 78 395 207 A0JM23 2.1e-41 Nephrocystin-3 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cilium assembly [GO:0060271]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; Wnt signaling pathway [GO:0016055] GO:0005929; GO:0016055; GO:0060271; GO:0090090; GO:2000095 18037 XM_044322902.1 297 108 13 78 117 Q95SX7 6.78e-26 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 18038 XM_029357240.2 54 72 37 47 63 NA NA NA NA NA NA 18039 XM_044315479.1 0 1 0 213 0 NA NA NA NA NA NA 18040 XR_006396999.1 13 0 0 0 64 NA NA NA NA NA NA 18041 XM_044307257.1 8 0 1 0 4 NA NA NA NA NA NA 18042 XM_029343147.2 690 340 207 623 510 A7S4N4 9.88e-128 Probable serine incorporator Nematostella vectensis (Starlet sea anemone) phospholipid biosynthetic process [GO:0008654] GO:0005789; GO:0008654; GO:0016020 18043 XR_006395940.1 7 0 6 0 6 NA NA NA NA NA NA 18044 XM_044316452.1 26 38 12 25 47 NA NA NA NA NA NA 18045 XM_029355267.2 0 0 0 0 42 Q9EQC4 7.38e-65 Elongation of very long chain fatty acids protein 4 (EC 2.3.1.199) (3-keto acyl-CoA synthase Elovl4) (ELOVL fatty acid elongase 4) (ELOVL FA elongase 4) (Very long chain 3-ketoacyl-CoA synthase 4) (Very long chain 3-oxoacyl-CoA synthase 4) Mus musculus (Mouse) fatty acid elongation, monounsaturated fatty acid [GO:0034625]; fatty acid elongation, polyunsaturated fatty acid [GO:0034626]; fatty acid elongation, saturated fatty acid [GO:0019367]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; sphingolipid biosynthetic process [GO:0030148]; unsaturated fatty acid biosynthetic process [GO:0006636]; very long-chain fatty acid biosynthetic process [GO:0042761] GO:0005783; GO:0005789; GO:0006636; GO:0009922; GO:0019367; GO:0030148; GO:0034625; GO:0034626; GO:0035338; GO:0042761; GO:0102756 18046 XM_044308431.1 225 89 171 617 257 P10586 1.78e-28 Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) (Leukocyte common antigen related) (LAR) Homo sapiens (Human) cell adhesion [GO:0007155]; cell migration [GO:0016477]; negative regulation of receptor binding [GO:1900121]; neuron projection regeneration [GO:0031102]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of axon regeneration [GO:0048679]; synaptic membrane adhesion [GO:0099560]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185] GO:0004725; GO:0005001; GO:0005886; GO:0006470; GO:0007155; GO:0007185; GO:0008201; GO:0016477; GO:0031102; GO:0035335; GO:0035373; GO:0043005; GO:0043025; GO:0044877; GO:0048679; GO:0050839; GO:0070062; GO:0099560; GO:1900121 18047 XM_044308431.1 225 89 171 617 257 P10586 1.68e-22 Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) (Leukocyte common antigen related) (LAR) Homo sapiens (Human) cell adhesion [GO:0007155]; cell migration [GO:0016477]; negative regulation of receptor binding [GO:1900121]; neuron projection regeneration [GO:0031102]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of axon regeneration [GO:0048679]; synaptic membrane adhesion [GO:0099560]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185] GO:0004725; GO:0005001; GO:0005886; GO:0006470; GO:0007155; GO:0007185; GO:0008201; GO:0016477; GO:0031102; GO:0035335; GO:0035373; GO:0043005; GO:0043025; GO:0044877; GO:0048679; GO:0050839; GO:0070062; GO:0099560; GO:1900121 18048 XM_029334039.2 209 153 90 227 146 Q81E85 3.31e-34 DEAD-box ATP-dependent RNA helicase CshC (EC 3.6.4.13) Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711) ribosomal large subunit assembly [GO:0000027] GO:0000027; GO:0003723; GO:0003724; GO:0005524; GO:0005829; GO:0016887; GO:0033592 18049 XM_029324263.2 326 261 233 419 373 Q91YU8 4.2e-109 Suppressor of SWI4 1 homolog (Ssf-1) (Peter Pan homolog) Mus musculus (Mouse) regulation of cell growth by extracellular stimulus [GO:0001560]; ribosomal large subunit assembly [GO:0000027]; rRNA processing [GO:0006364] GO:0000027; GO:0001560; GO:0005634; GO:0005730; GO:0006364; GO:0019843; GO:0030687 18050 XM_029338586.2 281 137 34 466 275 Q13976 0 cGMP-dependent protein kinase 1 (cGK 1) (cGK1) (EC 2.7.11.12) (cGMP-dependent protein kinase I) (cGKI) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cGMP-mediated signaling [GO:0019934]; collateral sprouting [GO:0048668]; dendrite development [GO:0016358]; forebrain development [GO:0030900]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; negative regulation of vascular associated smooth muscle cell proliferation [GO:1904706]; neuron migration [GO:0001764]; protein phosphorylation [GO:0006468]; regulation of GTPase activity [GO:0043087]; relaxation of vascular associated smooth muscle [GO:0060087]; signal transduction [GO:0007165] GO:0001764; GO:0004672; GO:0004692; GO:0005246; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005886; GO:0006468; GO:0007165; GO:0016358; GO:0019934; GO:0030036; GO:0030553; GO:0030900; GO:0042802; GO:0043087; GO:0048668; GO:0060087; GO:0090331; GO:0106310; GO:1904706; GO:1904753 18051 XM_029350046.2 359 330 23 171 95 Q90ZC7 0 Calcium-activated potassium channel subunit alpha-1 (BK channel) (BKCA alpha) (Calcium-activated potassium channel, subfamily M subunit alpha-1) (K(VCA)alpha) (KCa1.1) (Maxi K channel) (MaxiK) (Slo-alpha) (Slo1) (Slowpoke homolog) (Slo homolog) (xSlo) Xenopus laevis (African clawed frog) regulation of ion transmembrane transport [GO:0034765] GO:0005244; GO:0005267; GO:0016020; GO:0034765; GO:0046872 18052 XM_029343511.2 63 51 35 21 64 NA NA NA NA NA NA 18053 XM_044314119.1 295 256 180 318 387 Q9QUR6 2.78e-59 Prolyl endopeptidase (PE) (EC 3.4.21.26) (Post-proline cleaving enzyme) Mus musculus (Mouse) protein catabolic process [GO:0030163]; protein metabolic process [GO:0019538]; proteolysis [GO:0006508] GO:0004175; GO:0004252; GO:0005634; GO:0005737; GO:0005829; GO:0006508; GO:0019538; GO:0030163; GO:0042277; GO:0070012 18054 XM_044329275.1 0 7 0 0 0 NA NA NA NA NA NA 18055 XR_006392816.1 72 225 335 291 873 NA NA NA NA NA NA 18056 XM_044325012.1 11 0 0 15 0 P04323 3.92e-64 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 18057 XR_006391612.1 3438 2678 1397 3701 3726 Q0EEE2 7.78e-30 Patched domain-containing protein 3 (RND-type protein RNDEu-3) Mus musculus (Mouse) NA GO:0005783; GO:0005789; GO:0005886; GO:0016020; GO:0097225 18058 XM_029333778.2 0 54 0 324 643 Q7TN88 2.87e-68 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 18059 XM_029333778.2 0 54 0 324 643 Q7TN88 2.86e-49 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 18060 XM_044328523.1 15 0 11 8 29 Q9YHV3 3.45e-33 Noggin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cartilage development [GO:0051216]; cloaca development [GO:0035844]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic viscerocranium morphogenesis [GO:0048703]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell differentiation [GO:0045596]; osteoblast differentiation [GO:0001649]; pronephros development [GO:0048793] GO:0001649; GO:0005615; GO:0007368; GO:0009953; GO:0030514; GO:0035844; GO:0045596; GO:0048703; GO:0048793; GO:0051216 18061 XM_044321912.1 0 0 0 0 81 Q8IRC7 6.62e-77 LIM/homeobox protein Awh (Protein arrowhead) Drosophila melanogaster (Fruit fly) compound eye development [GO:0048749]; imaginal disc development [GO:0007444]; neuron differentiation [GO:0030182]; regulation of DNA-templated transcription [GO:0006355]; regulation of gene expression [GO:0010468]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000977; GO:0000981; GO:0003700; GO:0005634; GO:0006355; GO:0006357; GO:0007444; GO:0010468; GO:0030182; GO:0046872; GO:0048749 18062 XM_029330246.2 828 271 14 179 534 Q03164 3.8e-123 Histone-lysine N-methyltransferase 2A (Lysine N-methyltransferase 2A) (EC 2.1.1.364) (ALL-1) (CXXC-type zinc finger protein 7) (Cysteine methyltransferase KMT2A) (EC 2.1.1.-) (Myeloid/lymphoid or mixed-lineage leukemia) (Myeloid/lymphoid or mixed-lineage leukemia protein 1) (Trithorax-like protein) (Zinc finger protein HRX) [Cleaved into: MLL cleavage product N320 (N-terminal cleavage product of 320 kDa) (p320); MLL cleavage product C180 (C-terminal cleavage product of 180 kDa) (p180)] Homo sapiens (Human) anterior/posterior pattern specification [GO:0009952]; apoptotic process [GO:0006915]; circadian regulation of gene expression [GO:0032922]; definitive hemopoiesis [GO:0060216]; DNA methylation [GO:0006306]; embryonic hemopoiesis [GO:0035162]; exploration behavior [GO:0035640]; fibroblast proliferation [GO:0048144]; histone H3-K4 dimethylation [GO:0044648]; histone H3-K4 methylation [GO:0051568]; histone H3-K4 monomethylation [GO:0097692]; histone H3-K4 trimethylation [GO:0080182]; histone modification [GO:0016570]; homeostasis of number of cells within a tissue [GO:0048873]; membrane depolarization [GO:0051899]; negative regulation of DNA methylation [GO:1905642]; negative regulation of fibroblast proliferation [GO:0048147]; peptidyl-lysine monomethylation [GO:0018026]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transporter activity [GO:0032411]; post-embryonic development [GO:0009791]; protein-containing complex assembly [GO:0065003]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; response to potassium ion [GO:0035864]; spleen development [GO:0048536]; T-helper 2 cell differentiation [GO:0045064]; transcription initiation-coupled chromatin remodeling [GO:0045815]; visual learning [GO:0008542] GO:0003680; GO:0003682; GO:0005634; GO:0005654; GO:0005829; GO:0006306; GO:0006915; GO:0008270; GO:0008542; GO:0009791; GO:0009952; GO:0016570; GO:0018026; GO:0032411; GO:0032922; GO:0035097; GO:0035162; GO:0035640; GO:0035864; GO:0042800; GO:0042802; GO:0042803; GO:0044648; GO:0045064; GO:0045322; GO:0045815; GO:0045893; GO:0045944; GO:0048144; GO:0048147; GO:0048172; GO:0048536; GO:0048873; GO:0051568; GO:0051899; GO:0060216; GO:0065003; GO:0070577; GO:0071339; GO:0080182; GO:0097692; GO:0106363; GO:0140945; GO:1905642 18063 XM_029330246.2 828 271 14 179 534 Q03164 1.63e-100 Histone-lysine N-methyltransferase 2A (Lysine N-methyltransferase 2A) (EC 2.1.1.364) (ALL-1) (CXXC-type zinc finger protein 7) (Cysteine methyltransferase KMT2A) (EC 2.1.1.-) (Myeloid/lymphoid or mixed-lineage leukemia) (Myeloid/lymphoid or mixed-lineage leukemia protein 1) (Trithorax-like protein) (Zinc finger protein HRX) [Cleaved into: MLL cleavage product N320 (N-terminal cleavage product of 320 kDa) (p320); MLL cleavage product C180 (C-terminal cleavage product of 180 kDa) (p180)] Homo sapiens (Human) anterior/posterior pattern specification [GO:0009952]; apoptotic process [GO:0006915]; circadian regulation of gene expression [GO:0032922]; definitive hemopoiesis [GO:0060216]; DNA methylation [GO:0006306]; embryonic hemopoiesis [GO:0035162]; exploration behavior [GO:0035640]; fibroblast proliferation [GO:0048144]; histone H3-K4 dimethylation [GO:0044648]; histone H3-K4 methylation [GO:0051568]; histone H3-K4 monomethylation [GO:0097692]; histone H3-K4 trimethylation [GO:0080182]; histone modification [GO:0016570]; homeostasis of number of cells within a tissue [GO:0048873]; membrane depolarization [GO:0051899]; negative regulation of DNA methylation [GO:1905642]; negative regulation of fibroblast proliferation [GO:0048147]; peptidyl-lysine monomethylation [GO:0018026]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transporter activity [GO:0032411]; post-embryonic development [GO:0009791]; protein-containing complex assembly [GO:0065003]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; response to potassium ion [GO:0035864]; spleen development [GO:0048536]; T-helper 2 cell differentiation [GO:0045064]; transcription initiation-coupled chromatin remodeling [GO:0045815]; visual learning [GO:0008542] GO:0003680; GO:0003682; GO:0005634; GO:0005654; GO:0005829; GO:0006306; GO:0006915; GO:0008270; GO:0008542; GO:0009791; GO:0009952; GO:0016570; GO:0018026; GO:0032411; GO:0032922; GO:0035097; GO:0035162; GO:0035640; GO:0035864; GO:0042800; GO:0042802; GO:0042803; GO:0044648; GO:0045064; GO:0045322; GO:0045815; GO:0045893; GO:0045944; GO:0048144; GO:0048147; GO:0048172; GO:0048536; GO:0048873; GO:0051568; GO:0051899; GO:0060216; GO:0065003; GO:0070577; GO:0071339; GO:0080182; GO:0097692; GO:0106363; GO:0140945; GO:1905642 18064 XM_044309764.1 1 12 2 6 24 NA NA NA NA NA NA 18065 XR_006397249.1 90 527 31 49 56 NA NA NA NA NA NA 18066 XM_044313764.1 122 137 171 116 188 NA NA NA NA NA NA 18067 XM_044323945.1 546 620 282 360 218 A2A3L6 5.93e-57 Tetratricopeptide repeat protein 24 (TPR repeat protein 24) Homo sapiens (Human) NA NA 18068 XR_006395204.1 27 3 50 12 49 NA NA NA NA NA NA 18069 XM_044327495.1 0 1417 465 157 1772 NA NA NA NA NA NA 18070 XR_003825616.2 72 47 31 33 52 NA NA NA NA NA NA 18071 XM_044310719.1 0 0 0 9 0 NA NA NA NA NA NA 18072 XM_044319485.1 4234 1371 1882 4466 6834 NA NA NA NA NA NA 18073 XR_006394462.1 329 173 127 338 441 NA NA NA NA NA NA 18074 XM_044317088.1 216 9 256 217 203 Q9N126 8.04e-54 Retinol dehydrogenase 8 (EC 1.1.1.300) (Photoreceptor outer segment all-trans retinol dehydrogenase) Bos taurus (Bovine) estrogen biosynthetic process [GO:0006703]; response to stimulus [GO:0050896]; retinol metabolic process [GO:0042572]; visual perception [GO:0007601] GO:0004303; GO:0004745; GO:0005829; GO:0006703; GO:0007601; GO:0016491; GO:0042572; GO:0042622; GO:0050896; GO:0052650 18075 XM_044327930.1 1155 1005 893 1276 2548 Q9Y2E4 0 Disco-interacting protein 2 homolog C (DIP2 homolog C) Homo sapiens (Human) NA NA 18076 XM_044317641.1 86 167 19 318 399 Q8CG45 2.84e-110 Aflatoxin B1 aldehyde reductase member 2 (rAFAR2) (EC 1.1.1.n11) (Succinic semialdehyde reductase) (SSA reductase) Rattus norvegicus (Rat) daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; lipid metabolic process [GO:0006629] GO:0004032; GO:0004033; GO:0005635; GO:0005737; GO:0005739; GO:0005794; GO:0005795; GO:0006629; GO:0019119; GO:0044597; GO:0044598 18077 XM_029325474.2 511 371 224 370 347 A0JM24 1.68e-48 NADP-dependent oxidoreductase domain-containing protein 1 (EC 1.-.-.-) (Pyrroline-5-carboxylate reductase-like protein C14orf148 homolog) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0016491 18078 XM_044310696.1 123 0 39 311 0 B3EWZ8 9.69e-24 Ectin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 18079 XM_044324299.1 392 543 350 469 658 Q5QD04 1.28e-21 Trace amine-associated receptor 9 (TaR-9) (Trace amine receptor 9) (mTaar9) Mus musculus (Mouse) NA GO:0001594; GO:0005886 18080 XM_029328619.2 221 89 100 111 169 Q1WK23 1.15e-38 Serine protease 23 (EC 3.4.21.-) Macaca mulatta (Rhesus macaque) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 18081 XR_003825487.2 12 40 9 7 42 NA NA NA NA NA NA 18082 XM_029341045.2 175 154 76 145 122 Q8VCK5 7.45e-44 Kelch-like protein 20 (Kelch-like ECT2-interacting protein) Mus musculus (Mouse) Golgi to endosome transport [GO:0006895]; negative regulation of apoptotic process [GO:0043066]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K33-linked ubiquitination [GO:1990390]; protein transport [GO:0015031]; protein ubiquitination [GO:0016567] GO:0003779; GO:0004842; GO:0005737; GO:0005794; GO:0005802; GO:0005829; GO:0006895; GO:0015031; GO:0016567; GO:0016605; GO:0019964; GO:0030424; GO:0030425; GO:0031463; GO:0043066; GO:0043161; GO:0048471; GO:1990390 18083 XM_044308381.1 0 0 0 0 20 NA NA NA NA NA NA 18084 XM_044329003.1 0 0 58 0 345 NA NA NA NA NA NA 18085 XM_044308415.1 66 60 57 87 205 NA NA NA NA NA NA 18086 XM_029347061.2 0 0 0 0 186 P42893 1.61e-156 Endothelin-converting enzyme 1 (ECE-1) (EC 3.4.24.71) Rattus norvegicus (Rat) apoptotic process [GO:0006915]; axonogenesis involved in innervation [GO:0060385]; blood vessel diameter maintenance [GO:0097746]; bradykinin catabolic process [GO:0010815]; calcitonin catabolic process [GO:0010816]; ear development [GO:0043583]; embryonic digit morphogenesis [GO:0042733]; embryonic heart tube development [GO:0035050]; endothelin maturation [GO:0034959]; gene expression [GO:0010467]; heart development [GO:0007507]; hormone catabolic process [GO:0042447]; neuron projection development [GO:0031175]; peptide hormone processing [GO:0016486]; pharyngeal system development [GO:0060037]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of receptor recycling [GO:0001921]; protein processing [GO:0016485]; regulation of blood pressure [GO:0008217]; regulation of ERK1 and ERK2 cascade [GO:0070372]; response to cadmium ion [GO:0046686]; response to hypoxia [GO:0001666]; response to muscle stretch [GO:0035994]; response to xenobiotic stimulus [GO:0009410]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; substance P catabolic process [GO:0010814]; sympathetic neuron axon guidance [GO:0097492] GO:0001666; GO:0001921; GO:0004175; GO:0004222; GO:0005768; GO:0005769; GO:0005886; GO:0006915; GO:0007507; GO:0008217; GO:0008270; GO:0009410; GO:0009897; GO:0010467; GO:0010613; GO:0010814; GO:0010815; GO:0010816; GO:0016020; GO:0016485; GO:0016486; GO:0030141; GO:0031175; GO:0031410; GO:0031982; GO:0033093; GO:0034959; GO:0035050; GO:0035994; GO:0042447; GO:0042733; GO:0042802; GO:0042803; GO:0043583; GO:0043950; GO:0045745; GO:0046686; GO:0048471; GO:0060037; GO:0060385; GO:0070372; GO:0097492; GO:0097746; GO:1902287 18087 XM_044318000.1 231 212 165 208 244 Q6AZN4 1.23e-50 39S ribosomal protein L15, mitochondrial (L15mt) (MRP-L15) Xenopus laevis (African clawed frog) translation [GO:0006412] GO:0003735; GO:0005762; GO:0006412 18088 XR_003824368.2 53 50 74 66 51 NA NA NA NA NA NA 18089 XR_006396213.1 0 12 17 2 1 NA NA NA NA NA NA 18090 XM_044318798.1 50 2 21 55 61 P17124 2.81e-21 Histamine H2 receptor (H2R) (HH2R) (Gastric receptor I) Canis lupus familiaris (Dog) (Canis familiaris) chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; gastric acid secretion [GO:0001696]; positive regulation of vasoconstriction [GO:0045907] GO:0001696; GO:0004969; GO:0004993; GO:0005886; GO:0007187; GO:0007268; GO:0030425; GO:0030594; GO:0045202; GO:0045907 18091 XR_006393083.1 41 2 25 5 151 NA NA NA NA NA NA 18092 XM_044323908.1 0 3 4 27 6 P07911 2.24e-47 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Homo sapiens (Human) antibacterial innate immune response [GO:0140367]; apoptotic signaling pathway [GO:0097190]; autophagy [GO:0006914]; cellular calcium ion homeostasis [GO:0006874]; cellular chloride ion homeostasis [GO:0030644]; cellular defense response [GO:0006968]; cellular phosphate ion homeostasis [GO:0030643]; cellular response to unfolded protein [GO:0034620]; cellular sodium ion homeostasis [GO:0006883]; chaperone-mediated protein folding [GO:0061077]; citric acid secretion [GO:0046720]; collecting duct development [GO:0072044]; connective tissue replacement [GO:0097709]; creatinine homeostasis [GO:0097273]; defense response to Gram-negative bacterium [GO:0050829]; endoplasmic reticulum organization [GO:0007029]; glomerular filtration [GO:0003094]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; juxtaglomerular apparatus development [GO:0072051]; leukocyte cell-cell adhesion [GO:0007159]; lipid metabolic process [GO:0006629]; metanephric ascending thin limb development [GO:0072218]; metanephric distal convoluted tubule development [GO:0072221]; metanephric thick ascending limb development [GO:0072233]; micturition [GO:0060073]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell population proliferation [GO:0008285]; neutrophil migration [GO:1990266]; organ or tissue specific immune response [GO:0002251]; peptidyl-threonine phosphorylation [GO:0018107]; potassium ion homeostasis [GO:0055075]; protein localization to vacuole [GO:0072665]; protein transport into plasma membrane raft [GO:0044861]; regulation of blood pressure [GO:0008217]; regulation of protein transport [GO:0051223]; regulation of urine volume [GO:0035809]; renal sodium ion absorption [GO:0070294]; renal urate salt excretion [GO:0097744]; renal water homeostasis [GO:0003091]; response to lipopolysaccharide [GO:0032496]; response to water deprivation [GO:0009414]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; ubiquitin-dependent ERAD pathway [GO:0030433]; urate transport [GO:0015747]; urea transmembrane transport [GO:0071918] GO:0000922; GO:0002251; GO:0003091; GO:0003094; GO:0005201; GO:0005509; GO:0005615; GO:0005783; GO:0005796; GO:0005929; GO:0006629; GO:0006874; GO:0006883; GO:0006914; GO:0006954; GO:0006968; GO:0007029; GO:0007157; GO:0007159; GO:0008217; GO:0008285; GO:0008380; GO:0009410; GO:0009414; GO:0009986; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0018107; GO:0019864; GO:0019898; GO:0030433; GO:0030643; GO:0030644; GO:0032496; GO:0033209; GO:0033555; GO:0034620; GO:0035809; GO:0044861; GO:0046720; GO:0050829; GO:0051223; GO:0055075; GO:0060073; GO:0060170; GO:0061077; GO:0070062; GO:0070294; GO:0071918; GO:0072044; GO:0072051; GO:0072218; GO:0072221; GO:0072233; GO:0072665; GO:0097190; GO:0097273; GO:0097709; GO:0097744; GO:0140367; GO:1990266 18093 XR_003826787.2 108 181 59 117 48 NA NA NA NA NA NA 18094 XR_006396763.1 3 0 9 54 28 NA NA NA NA NA NA 18095 XM_044327860.1 3 0 48 21 8 Q94K49 1.35e-26 Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1 (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) epigenetic regulation of gene expression [GO:0040029] GO:0003682; GO:0004518; GO:0005634; GO:0035098; GO:0035102; GO:0040029; GO:0046872 18096 XM_029337315.2 790 84 265 168 290 F1R8P4 8.71e-52 Glycine receptor subunit alpha-2 Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0004888; GO:0005254; GO:0016594; GO:0016933; GO:0022824; GO:0034707; GO:0042995; GO:0045211; GO:0046872 18097 XM_044317792.1 39 11 52 32 24 NA NA NA NA NA NA 18098 XM_044315749.1 10 0 3 2 0 NA NA NA NA NA NA 18099 XM_044323927.1 29 19 11 9 12 Q91ZV3 2.11e-23 Discoidin, CUB and LCCL domain-containing protein 2 (Endothelial and smooth muscle cell-derived neuropilin-like protein) Mus musculus (Mouse) negative regulation of cell growth [GO:0030308]; wound healing [GO:0042060] GO:0005886; GO:0009986; GO:0030308; GO:0038023; GO:0042060 18100 XM_044320281.1 100 831 504 876 868 P10079 2.93e-115 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 18101 XM_044320281.1 100 831 504 876 868 P10079 1.34e-113 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 18102 XM_044320281.1 100 831 504 876 868 P10079 4.7e-111 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 18103 XM_044320281.1 100 831 504 876 868 P10079 1.56e-104 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 18104 XM_044320281.1 100 831 504 876 868 P10079 9.5e-52 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 18105 XM_044328478.1 906 565 622 1121 1216 NA NA NA NA NA NA 18106 XM_029337689.2 0 73 36 61 134 NA NA NA NA NA NA 18107 XR_006396299.1 0 0 0 80 48 NA NA NA NA NA NA 18108 XM_044318286.1 71 2 42 2 361 Q99715 3.5e-24 Collagen alpha-1(XII) chain Homo sapiens (Human) cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; endodermal cell differentiation [GO:0035987] GO:0005576; GO:0005595; GO:0005615; GO:0005788; GO:0007155; GO:0030020; GO:0030199; GO:0035987; GO:0062023; GO:0070062; GO:1903561 18109 XM_044318286.1 71 2 42 2 361 Q99715 1.06e-21 Collagen alpha-1(XII) chain Homo sapiens (Human) cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; endodermal cell differentiation [GO:0035987] GO:0005576; GO:0005595; GO:0005615; GO:0005788; GO:0007155; GO:0030020; GO:0030199; GO:0035987; GO:0062023; GO:0070062; GO:1903561 18110 XM_044327846.1 5 0 18 6 67 NA NA NA NA NA NA 18111 XM_029335791.2 60 224 0 116 0 NA NA NA NA NA NA 18112 XR_003824987.2 0 0 12 2 50 NA NA NA NA NA NA 18113 XM_044309553.1 2206 1469 1272 2153 2115 Q921M4 3.44e-55 Golgin subfamily A member 2 (130 kDa cis-Golgi matrix protein) (GM130) Mus musculus (Mouse) asymmetric cell division [GO:0008356]; axonogenesis [GO:0007409]; centrosome cycle [GO:0007098]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi disassembly [GO:0090166]; Golgi localization [GO:0051645]; Golgi organization [GO:0007030]; Golgi ribbon formation [GO:0090161]; meiotic spindle assembly [GO:0090306]; microtubule nucleation [GO:0007020]; mitotic spindle assembly [GO:0090307]; negative regulation of autophagy [GO:0010507]; negative regulation of protein binding [GO:0032091]; positive regulation of axonogenesis [GO:0050772]; positive regulation of protein glycosylation [GO:0060050]; protein glycosylation [GO:0006486]; protein homotetramerization [GO:0051289]; protein transport [GO:0015031]; spindle assembly [GO:0051225] GO:0000137; GO:0000139; GO:0000922; GO:0005737; GO:0005794; GO:0005801; GO:0005874; GO:0006486; GO:0006888; GO:0007020; GO:0007030; GO:0007098; GO:0007409; GO:0008017; GO:0008356; GO:0010507; GO:0015031; GO:0019901; GO:0019905; GO:0030134; GO:0032091; GO:0032580; GO:0032991; GO:0033116; GO:0042802; GO:0043025; GO:0044877; GO:0048471; GO:0050772; GO:0051225; GO:0051289; GO:0051645; GO:0060050; GO:0061676; GO:0072686; GO:0090161; GO:0090166; GO:0090306; GO:0090307 18114 XR_006395165.1 16 6 16 52 25 NA NA NA NA NA NA 18115 XM_029336772.2 0 219 102 116 0 G5EDE1 1.28e-59 Zinc finger protein GFI1 homolog pag-3 (Pattern of reporter gene expression abnormal protein 3) (Transcription factor pag-3) Caenorhabditis elegans negative regulation of apoptotic process [GO:0043066]; negative regulation of insulin secretion [GO:0046676]; negative regulation of neurotransmitter secretion [GO:0046929]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuroblast fate specification [GO:0014018]; regulation of backward locomotion [GO:0043058]; regulation of forward locomotion [GO:0043059]; regulation of neuron differentiation [GO:0045664]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000978; GO:0001222; GO:0001227; GO:0003700; GO:0003714; GO:0005634; GO:0006357; GO:0014018; GO:0030424; GO:0043058; GO:0043059; GO:0043066; GO:0043204; GO:0045664; GO:0046676; GO:0046872; GO:0046929 18116 XM_029328245.2 19 1 6 0 33 P48039 9.31e-23 Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor) Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; circadian rhythm [GO:0007623]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; mating behavior [GO:0007617] GO:0004930; GO:0005886; GO:0007186; GO:0007187; GO:0007193; GO:0007617; GO:0007623; GO:0008502; GO:0042562; GO:0043235; GO:0097159 18117 XM_029345059.2 217 0 61 44 12 NA NA NA NA NA NA 18118 XM_029328159.2 1869 1080 1081 1269 1409 NA NA NA NA NA NA 18119 XM_044314976.1 536 405 499 525 494 P51163 1.3e-44 Uroporphyrinogen-III synthase (UROIIIS) (UROS) (EC 4.2.1.75) (Hydroxymethylbilane hydrolyase [cyclizing]) (Uroporphyrinogen-III cosynthase) Mus musculus (Mouse) cellular response to amine stimulus [GO:0071418]; cellular response to arsenic-containing substance [GO:0071243]; heme biosynthetic process [GO:0006783]; porphyrin-containing compound biosynthetic process [GO:0006779]; protoporphyrinogen IX biosynthetic process [GO:0006782]; response to antibiotic [GO:0046677]; response to platinum ion [GO:0070541]; uroporphyrinogen III biosynthetic process [GO:0006780] GO:0004852; GO:0005542; GO:0005739; GO:0005829; GO:0006779; GO:0006780; GO:0006782; GO:0006783; GO:0046677; GO:0070541; GO:0071243; GO:0071418 18120 XM_044309949.1 508 296 280 418 522 P18433 1.23e-133 Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (EC 3.1.3.48) Homo sapiens (Human) insulin receptor signaling pathway [GO:0008286]; integrin-mediated signaling pathway [GO:0007229]; modulation of chemical synaptic transmission [GO:0050804]; protein dephosphorylation [GO:0006470]; protein phosphorylation [GO:0006468]; regulation of focal adhesion assembly [GO:0051893] GO:0004725; GO:0005001; GO:0005886; GO:0005925; GO:0006468; GO:0006470; GO:0007229; GO:0008286; GO:0016020; GO:0043235; GO:0050804; GO:0051893; GO:0070062; GO:0097060; GO:0098685 18121 XM_029329042.2 0 0 0 76 0 O95801 2.59e-79 Tetratricopeptide repeat protein 4 (TPR repeat protein 4) Homo sapiens (Human) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; protein folding [GO:0006457] GO:0005634; GO:0005654; GO:0005737; GO:0006457; GO:0030544; GO:0045087; GO:0051607; GO:0051879 18122 XM_044322797.1 530 345 727 463 877 NA NA NA NA NA NA 18123 XM_029331564.2 1988 1303 1499 1620 2283 NA NA NA NA NA NA 18124 XM_029347251.2 3573 3394 4741 12694 6544 O35920 0 Calpain-9 (EC 3.4.22.-) (Digestive tract-specific calpain) (New calpain 4) (nCL-4) Rattus norvegicus (Rat) proteolysis [GO:0006508] GO:0004198; GO:0005509; GO:0005737; GO:0006508 18125 XR_006397911.1 28 82 23 88 69 NA NA NA NA NA NA 18126 XR_006397063.1 47 39 0 0 0 NA NA NA NA NA NA 18127 XM_029353477.2 774 456 463 587 342 A0A3L7I2I8 2.3e-149 85/88 kDa calcium-independent phospholipase A2 (CaI-PLA2) (EC 3.1.1.4) (2-lysophosphatidylcholine acylhydrolase) (EC 3.1.1.5) (Group VI phospholipase A2) (GVI PLA2) (Intracellular membrane-associated calcium-independent phospholipase A2 beta) (iPLA2-beta) (PLA2G6) (Palmitoyl-CoA hydrolase) (EC 3.1.2.2) (Patatin-like phospholipase domain-containing protein 9) (PNPLA9) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) antibacterial humoral response [GO:0019731]; cardiolipin acyl-chain remodeling [GO:0035965]; cardiolipin biosynthetic process [GO:0032049]; phosphatidic acid metabolic process [GO:0046473]; phosphatidylcholine catabolic process [GO:0034638]; phosphatidylethanolamine catabolic process [GO:0046338]; platelet activating factor metabolic process [GO:0046469]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774] GO:0003847; GO:0004622; GO:0005615; GO:0005739; GO:0005829; GO:0005886; GO:0016290; GO:0017171; GO:0019731; GO:0031143; GO:0032049; GO:0034451; GO:0034638; GO:0035774; GO:0035965; GO:0042802; GO:0046338; GO:0046469; GO:0046473; GO:0047499; GO:0102545; GO:0102991 18128 XM_044312539.1 0 5 7 4 27 Q96AY4 8.37e-154 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18129 XM_044312539.1 0 5 7 4 27 Q96AY4 3.56e-118 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18130 XM_044312539.1 0 5 7 4 27 Q96AY4 1.96e-116 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18131 XM_044312539.1 0 5 7 4 27 Q96AY4 6.33e-116 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18132 XM_044312539.1 0 5 7 4 27 Q96AY4 6.18e-104 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18133 XM_044310557.1 5 15 42 6 174 Q9VBW3 1.37e-61 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 18134 XM_044324061.1 106 166 39 91 31 NA NA NA NA NA NA 18135 XR_006397156.1 0 0 6 0 5 NA NA NA NA NA NA 18136 XM_044309445.1 211 224 198 227 283 O00602 2.55e-71 Ficolin-1 (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin-alpha) (M-ficolin) Homo sapiens (Human) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation, lectin pathway [GO:0001867]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of viral entry into host cell [GO:0046597]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of opsonization [GO:1903028]; protein localization to cell surface [GO:0034394]; proteolysis [GO:0006508]; recognition of apoptotic cell [GO:0043654] GO:0001664; GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005576; GO:0005581; GO:0005615; GO:0006508; GO:0007186; GO:0009897; GO:0030246; GO:0031232; GO:0032757; GO:0033691; GO:0034394; GO:0034774; GO:0038187; GO:0043654; GO:0046597; GO:0046872; GO:0062023; GO:0097367; GO:1903028; GO:1904813; GO:1905370 18137 XM_044317756.1 526 192 423 527 266 Q92051 2.02e-49 Carbonic anhydrase (EC 4.2.1.1) (Carbonate dehydratase) Danio rerio (Zebrafish) (Brachydanio rerio) carbon dioxide transport [GO:0015670]; hypotonic salinity response [GO:0042539]; one-carbon metabolic process [GO:0006730] GO:0004089; GO:0005737; GO:0006730; GO:0008270; GO:0015670; GO:0016836; GO:0042539 18138 XM_044307705.1 194 59 63 170 208 B3EX02 7.24e-128 MAM and fibronectin type III domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 18139 XM_044307705.1 194 59 63 170 208 B3EX02 2.45e-123 MAM and fibronectin type III domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 18140 XM_044315186.1 46 0 121 460 0 NA NA NA NA NA NA 18141 XM_044306846.1 0 0 0 79 15 Q8CCP0 0 Ribosome quality control complex subunit NEMF (Nuclear export mediator factor) (Serologically defined colon cancer antigen 1 homolog) Mus musculus (Mouse) CAT tailing [GO:0140708]; nuclear export [GO:0051168]; protein-containing complex assembly [GO:0065003]; rescue of stalled ribosome [GO:0072344]; ribosome-associated ubiquitin-dependent protein catabolic process [GO:1990116] GO:0000049; GO:0005634; GO:0005829; GO:0043023; GO:0051168; GO:0065003; GO:0072344; GO:0140708; GO:1990112; GO:1990116 18142 XM_044306846.1 0 0 0 79 15 Q8CCP0 4.93e-33 Ribosome quality control complex subunit NEMF (Nuclear export mediator factor) (Serologically defined colon cancer antigen 1 homolog) Mus musculus (Mouse) CAT tailing [GO:0140708]; nuclear export [GO:0051168]; protein-containing complex assembly [GO:0065003]; rescue of stalled ribosome [GO:0072344]; ribosome-associated ubiquitin-dependent protein catabolic process [GO:1990116] GO:0000049; GO:0005634; GO:0005829; GO:0043023; GO:0051168; GO:0065003; GO:0072344; GO:0140708; GO:1990112; GO:1990116 18143 XM_029341309.2 946 374 320 189 708 P46198 5.87e-165 Translation initiation factor IF-2, mitochondrial (IF-2(Mt)) (IF-2Mt) (IF2(mt)) Bos taurus (Bovine) mitochondrial translational initiation [GO:0070124]; ribosome disassembly [GO:0032790]; translational initiation [GO:0006413] GO:0003743; GO:0003924; GO:0005525; GO:0005654; GO:0005737; GO:0005739; GO:0005759; GO:0006413; GO:0008135; GO:0032790; GO:0043024; GO:0070124 18144 XR_006393159.1 21 1 7 3 16 NA NA NA NA NA NA 18145 XM_044314901.1 33 2 6 17 22 Q9DBN1 3.06e-37 Stimulated by retinoic acid gene 6 protein-like (STRA6-like protein) (Retinol-binding protein 4 receptor 2) (RBP4 receptor 2) Mus musculus (Mouse) establishment of localization in cell [GO:0051649]; retinol transport [GO:0034633]; vitamin A import into cell [GO:0071939] GO:0005886; GO:0034633; GO:0051649; GO:0071939 18146 XM_029348025.2 785 1928 876 1373 961 P77475 6.02e-26 Fructose-1-phosphate phosphatase YqaB (EC 3.1.3.-) (Fructose-1-phosphatase) Escherichia coli (strain K12) NA GO:0000287; GO:0008801; GO:0016791; GO:0050308 18147 XM_029358620.2 1157 340 311 1004 653 Q3UGY8 0 Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (ARFGEF family member 3) Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; regulation of ARF protein signal transduction [GO:0032012] GO:0005085; GO:0005794; GO:0030036; GO:0030658; GO:0032012 18148 XM_029358620.2 1157 340 311 1004 653 Q3UGY8 1.18e-75 Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (ARFGEF family member 3) Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; regulation of ARF protein signal transduction [GO:0032012] GO:0005085; GO:0005794; GO:0030036; GO:0030658; GO:0032012 18149 XM_044311128.1 117 0 22 5 28 NA NA NA NA NA NA 18150 XM_044328705.1 636 397 416 248 882 Q0P5X1 2.35e-56 Leucine-rich repeat and IQ domain-containing protein 1 Mus musculus (Mouse) NA GO:0005737; GO:0019901 18151 XM_044314219.1 0 9 0 0 0 NA NA NA NA NA NA 18152 XM_029353192.2 27 4 0 37 116 Q6NTR1 9.15e-121 eEF1A lysine and N-terminal methyltransferase (Methyltransferase-like protein 13) [Includes: eEF1A lysine methyltransferase (EC 2.1.1.-); eEF1A N-terminal methyltransferase (EC 2.1.1.-)] Xenopus laevis (African clawed frog) NA GO:0016279 18153 XM_044328100.1 136 0 0 4 0 NA NA NA NA NA NA 18154 XR_006392762.1 16 7 18 4 0 NA NA NA NA NA NA 18155 XM_044324279.1 35 43 43 37 79 Q5PQJ7 3.75e-90 Tubulin-specific chaperone cofactor E-like protein (Leucine-rich repeat-containing protein 35) Rattus norvegicus (Rat) microtubule cytoskeleton organization [GO:0000226]; post-chaperonin tubulin folding pathway [GO:0007023]; tubulin complex assembly [GO:0007021] GO:0000226; GO:0005737; GO:0005856; GO:0007021; GO:0007023; GO:0043014 18156 XM_044313788.1 9 2 1 0 0 NA NA NA NA NA NA 18157 XR_006396170.1 56 1 34 16 146 NA NA NA NA NA NA 18158 XM_029323852.2 70 47 62 70 120 Q566X8 1.6e-26 Diencephalon/mesencephalon homeobox protein 1-B Danio rerio (Zebrafish) (Brachydanio rerio) midbrain development [GO:0030901]; regulation of cell cycle [GO:0051726]; regulation of mitotic cell cycle [GO:0007346]; regulation of neural retina development [GO:0061074]; regulation of neurogenesis [GO:0050767]; regulation of transcription by RNA polymerase II [GO:0006357]; retina development in camera-type eye [GO:0060041] GO:0000977; GO:0000981; GO:0005634; GO:0006357; GO:0007346; GO:0030901; GO:0050767; GO:0051726; GO:0060041; GO:0061074 18159 XM_044328549.1 7 17 19 19 18 NA NA NA NA NA NA 18160 XM_029348073.2 4050 2953 1898 3313 4416 P00504 4.21e-160 Aspartate aminotransferase, cytoplasmic (cAspAT) (EC 2.6.1.1) (EC 2.6.1.3) (Cysteine aminotransferase, cytoplasmic) (Cysteine transaminase, cytoplasmic) (cCAT) (Glutamate oxaloacetate transaminase 1) (Transaminase A) Gallus gallus (Chicken) 2-oxoglutarate metabolic process [GO:0006103]; aspartate biosynthetic process [GO:0006532]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular response to insulin stimulus [GO:0032869]; fatty acid homeostasis [GO:0055089]; gluconeogenesis [GO:0006094]; glutamate catabolic process to 2-oxoglutarate [GO:0019551]; glutamate catabolic process to aspartate [GO:0019550]; glutamate metabolic process [GO:0006536]; glycerol biosynthetic process [GO:0006114]; Notch signaling pathway [GO:0007219]; oxaloacetate metabolic process [GO:0006107]; response to glucocorticoid [GO:0051384] GO:0004069; GO:0004609; GO:0005654; GO:0005829; GO:0006094; GO:0006103; GO:0006107; GO:0006114; GO:0006531; GO:0006532; GO:0006533; GO:0006536; GO:0007219; GO:0019550; GO:0019551; GO:0030170; GO:0032869; GO:0047801; GO:0051384; GO:0055089 18161 XM_044325984.1 0 0 26 13 186 NA NA NA NA NA NA 18162 XM_044323312.1 910 471 457 513 1147 P16157 5.64e-96 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 18163 XM_044323312.1 910 471 457 513 1147 P16157 1.17e-94 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 18164 XM_044323312.1 910 471 457 513 1147 P16157 3.23e-90 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 18165 XM_044323312.1 910 471 457 513 1147 P16157 8.23e-80 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 18166 XM_044323312.1 910 471 457 513 1147 P16157 5.11e-77 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 18167 XM_044323312.1 910 471 457 513 1147 P16157 5.43e-69 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 18168 XM_044323312.1 910 471 457 513 1147 P16157 7.24e-67 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 18169 XM_044323312.1 910 471 457 513 1147 P16157 2.51e-62 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 18170 XM_044323312.1 910 471 457 513 1147 P16157 1.12e-31 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 18171 XM_044323312.1 910 471 457 513 1147 P16157 6.06e-31 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 18172 XM_029339528.2 16 0 0 1 0 G3M4F8 1.42e-23 Octopamine receptor beta-2R (CsOA2B2) Chilo suppressalis (Asiatic rice borer moth) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cellular response to amine stimulus [GO:0071418]; octopamine signaling pathway [GO:0071927]; tyramine signaling pathway [GO:0071928] GO:0004989; GO:0005886; GO:0007189; GO:0008226; GO:0016020; GO:0071418; GO:0071927; GO:0071928 18173 XM_029331594.2 0 16 0 0 0 Q803U7 4.33e-97 Exonuclease 1 (EC 3.1.-.-) (Exonuclease I) Danio rerio (Zebrafish) (Brachydanio rerio) DNA recombination [GO:0006310]; mismatch repair [GO:0006298] GO:0003677; GO:0005634; GO:0006298; GO:0006310; GO:0017108; GO:0035312; GO:0045145; GO:0046872; GO:0048256 18174 XM_029349351.2 4 2 22 7 10 P06603 0 Tubulin alpha-1 chain (EC 3.6.5.-) Drosophila melanogaster (Fruit fly) lysosome localization [GO:0032418]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278] GO:0000226; GO:0000235; GO:0000278; GO:0005200; GO:0005525; GO:0005634; GO:0005737; GO:0005813; GO:0005819; GO:0005874; GO:0016787; GO:0032418; GO:0046872; GO:0048471 18175 XM_044316605.1 22 8 8 21 25 NA NA NA NA NA NA 18176 XR_006397657.1 0 0 6 0 0 NA NA NA NA NA NA 18177 XM_029357315.2 19555 25531 9658 12795 8733 P17078 4.51e-41 60S ribosomal protein L35 Rattus norvegicus (Rat) cellular response to UV-B [GO:0071493]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; translation [GO:0006412] GO:0000463; GO:0003729; GO:0003735; GO:0006412; GO:0022625; GO:0022626; GO:0043021; GO:0045202; GO:0071493 18178 XR_003825650.2 1320 1639 535 521 993 NA NA NA NA NA NA 18179 XM_029341464.2 44 0 57 0 128 Q9EQD2 1.97e-25 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 18180 XM_029327844.2 527 445 316 498 662 NA NA NA NA NA NA 18181 XR_006394047.1 246 145 151 84 220 NA NA NA NA NA NA 18182 XM_044316871.1 4 20 8 13 9 NA NA NA NA NA NA 18183 XM_029357624.2 762 394 525 801 731 Q8WWZ7 0 Cholesterol transporter ABCA5 (EC 7.6.2.-) (ATP-binding cassette sub-family A member 5) Homo sapiens (Human) cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; high-density lipoprotein particle remodeling [GO:0034375]; lipid transport [GO:0006869]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; positive regulation of reverse cholesterol transport [GO:1903064]; regulation of cholesterol efflux [GO:0010874]; reverse cholesterol transport [GO:0043691] GO:0000139; GO:0005319; GO:0005524; GO:0005764; GO:0005765; GO:0005770; GO:0005794; GO:0005886; GO:0006869; GO:0008203; GO:0010745; GO:0010874; GO:0016887; GO:0031902; GO:0033344; GO:0034375; GO:0042626; GO:0042632; GO:0043231; GO:0043691; GO:0140359; GO:1903064 18184 XM_029357624.2 762 394 525 801 731 Q8WWZ7 6.59e-45 Cholesterol transporter ABCA5 (EC 7.6.2.-) (ATP-binding cassette sub-family A member 5) Homo sapiens (Human) cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; high-density lipoprotein particle remodeling [GO:0034375]; lipid transport [GO:0006869]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; positive regulation of reverse cholesterol transport [GO:1903064]; regulation of cholesterol efflux [GO:0010874]; reverse cholesterol transport [GO:0043691] GO:0000139; GO:0005319; GO:0005524; GO:0005764; GO:0005765; GO:0005770; GO:0005794; GO:0005886; GO:0006869; GO:0008203; GO:0010745; GO:0010874; GO:0016887; GO:0031902; GO:0033344; GO:0034375; GO:0042626; GO:0042632; GO:0043231; GO:0043691; GO:0140359; GO:1903064 18185 XM_044322918.1 17 56 18 0 199 Q91398 1.32e-130 Casein kinase II subunit beta (CK II beta) Danio rerio (Zebrafish) (Brachydanio rerio) regulation of protein serine/threonine phosphatase activity [GO:0080163]; Wnt signaling pathway [GO:0016055] GO:0005737; GO:0005956; GO:0016055; GO:0019887; GO:0046872; GO:0080163 18186 XM_029337601.2 511 0 502 1232 766 NA NA NA NA NA NA 18187 XM_044312926.1 0 0 14 66 0 F8W2M8 1.78e-175 Tripeptidyl-peptidase 1 (TPP-1) (EC 3.4.14.9) (Tripeptidyl aminopeptidase) (Tripeptidyl-peptidase I) (TPP-I) Danio rerio (Zebrafish) (Brachydanio rerio) central nervous system development [GO:0007417]; locomotory behavior [GO:0007626]; neurogenesis [GO:0022008]; proteolysis [GO:0006508] GO:0004175; GO:0004252; GO:0005764; GO:0006508; GO:0007417; GO:0007626; GO:0008240; GO:0022008; GO:0046872 18188 XM_029334421.2 0 0 0 84 0 Q91981 1.69e-32 Homeobox protein OTX2 (zOTX2) (Orthodenticle homolog 2) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to alcohol [GO:0097306]; cerebellum development [GO:0021549]; hindbrain development [GO:0030902]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; regulation of transcription by RNA polymerase II [GO:0006357]; retinal pigment epithelium development [GO:0003406] GO:0000978; GO:0000981; GO:0003406; GO:0005634; GO:0006357; GO:0021549; GO:0030901; GO:0030902; GO:0030917; GO:0097306 18189 XM_029358617.2 6460 5236 3963 6553 4090 D3ZDI6 2.07e-116 E3 ubiquitin-protein ligase MYLIP (EC 2.3.2.27) (Inducible degrader of the LDL-receptor) (Idol) (Myosin regulatory light chain interacting protein) (MIR) (RING-type E3 ubiquitin transferase MYLIP) Rattus norvegicus (Rat) cholesterol homeostasis [GO:0042632]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of neuron projection development [GO:0010977]; nervous system development [GO:0007399]; positive regulation of protein catabolic process [GO:0045732]; protein destabilization [GO:0031648]; protein ubiquitination [GO:0016567]; regulation of low-density lipoprotein particle receptor catabolic process [GO:0032803]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004842; GO:0005737; GO:0005856; GO:0005886; GO:0006511; GO:0007399; GO:0008092; GO:0010977; GO:0010989; GO:0016567; GO:0031648; GO:0032803; GO:0042632; GO:0045732; GO:0046872; GO:0061630 18190 XM_029337152.2 21380 8994 6820 12488 10169 NA NA NA NA NA NA 18191 XM_044306918.1 8 0 5 0 0 NA NA NA NA NA NA 18192 XM_044321415.1 19 37 27 34 26 O57525 1.35e-78 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Rana dybowskii (Dybovsky's frog) (Korean brown frog) steroid biosynthetic process [GO:0006694] GO:0004508; GO:0005506; GO:0006694; GO:0016020; GO:0020037; GO:0047442 18193 XR_006395327.1 0 0 0 172 97 NA NA NA NA NA NA 18194 XM_029324638.2 542 375 287 415 439 Q6ZV70 8.39e-112 LanC-like protein 3 Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; peptide modification [GO:0031179] GO:0005886; GO:0005975; GO:0031179 18195 XM_044318456.1 50 21 57 26 55 E7FAM5 6.88e-90 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 18196 XM_044318456.1 50 21 57 26 55 E7FAM5 2.3e-80 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 18197 XM_044318456.1 50 21 57 26 55 E7FAM5 6.4e-32 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 18198 XM_044318456.1 50 21 57 26 55 E7FAM5 3.41e-31 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 18199 XM_044318456.1 50 21 57 26 55 E7FAM5 9.29e-29 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 18200 XR_006396061.1 24 13 0 21 27 NA NA NA NA NA NA 18201 XM_044319277.1 13 6 18 20 68 Q7Z442 2.12e-71 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Homo sapiens (Human) detection of mechanical stimulus [GO:0050982] GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 18202 XM_044319277.1 13 6 18 20 68 Q7Z442 4.29e-48 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Homo sapiens (Human) detection of mechanical stimulus [GO:0050982] GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 18203 XM_029351137.2 473 354 413 461 647 Q9Z2Z3 2.97e-22 Peroxisomal membrane protein PEX14 (PTS1 receptor-docking protein) (Peroxin-14) (Peroxisomal membrane anchor protein PEX14) Cricetulus longicaudatus (Long-tailed dwarf hamster) (Chinese hamster) negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA-templated transcription [GO:0045892]; protein import into peroxisome matrix [GO:0016558]; protein import into peroxisome matrix, docking [GO:0016560] GO:0003714; GO:0005777; GO:0005778; GO:0008320; GO:0016558; GO:0016560; GO:0030674; GO:0042802; GO:0043433; GO:0045892; GO:0047485 18204 XM_029338728.2 41 16 61 48 83 NA NA NA NA NA NA 18205 XM_029333143.2 1526 1535 985 1209 1325 Q3C1E9 5.06e-74 Histone chaperone ASF1 (Anti-silencing function protein 1 homolog) Gallus gallus (Chicken) DNA replication-dependent chromatin assembly [GO:0006335] GO:0005634; GO:0006335; GO:0042393 18206 XM_029327569.2 73 75 27 71 31 NA NA NA NA NA NA 18207 XR_003823594.2 34 209 0 0 0 NA NA NA NA NA NA 18208 XM_029358621.2 18299 13780 11287 17671 17734 NA NA NA NA NA NA 18209 XM_044326433.1 65 0 44 5 162 NA NA NA NA NA NA 18210 XM_044308974.1 263 124 33 117 189 NA NA NA NA NA NA 18211 XR_006392502.1 84 6 27 106 67 NA NA NA NA NA NA 18212 XM_029331314.2 395 361 203 204 41 Q8BGK5 9.79e-100 Solute carrier family 35 member F1 Mus musculus (Mouse) NA GO:0016020; GO:0022857 18213 XR_003825171.2 254 209 156 255 336 NA NA NA NA NA NA 18214 XM_029332334.2 0 7 0 0 0 NA NA NA NA NA NA 18215 XR_006394732.1 20 0 19 17 22 NA NA NA NA NA NA 18216 XM_029348312.2 0 0 10 0 17 NA NA NA NA NA NA 18217 XM_029333132.2 299 127 266 257 400 A2VDD2 2.41e-21 Dynein light chain Tctex-type 5-B (Tctex1 domain-containing protein 1-B) Xenopus laevis (African clawed frog) NA NA 18218 XM_029333206.2 34 0 0 0 61 A0A1L8GWK2 8.67e-159 NA NA NA NA 18219 XR_006394358.1 7 5 39 2 11 NA NA NA NA NA NA 18220 XR_006393388.1 1 0 10 6 0 NA NA NA NA NA NA 18221 XM_029331304.2 1121 676 564 730 497 Q6DGL2 7.13e-45 NF-kappa-B inhibitor-interacting Ras-like protein 2 (I-kappa-B-interacting Ras-like protein 2) (Kappa B-Ras protein 2) (KappaB-Ras2) Danio rerio (Zebrafish) (Brachydanio rerio) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; Ral protein signal transduction [GO:0032484]; surfactant homeostasis [GO:0043129] GO:0003924; GO:0005525; GO:0005737; GO:0007249; GO:0032484; GO:0032794; GO:0043129 18222 XM_044316169.1 0 0 0 7 0 NA NA NA NA NA NA 18223 XR_003825160.2 0 0 150 48 449 NA NA NA NA NA NA 18224 XM_044315796.1 0 0 0 18 8 NA NA NA NA NA NA 18225 XM_029338035.2 22 12 11 21 55 NA NA NA NA NA NA 18226 XM_044308173.1 233 231 169 97 145 NA NA NA NA NA NA 18227 XM_044321437.1 80 6 35 63 49 NA NA NA NA NA NA 18228 XM_029357339.2 2 0 0 173 0 P22770 1.79e-72 Neuronal acetylcholine receptor subunit alpha-7 Gallus gallus (Chicken) calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; cognition [GO:0050890]; membrane depolarization [GO:0051899]; negative regulation of tumor necrosis factor production [GO:0032720]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAPK cascade [GO:0043410]; regulation of nitric oxide metabolic process [GO:0080164]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; signal transduction [GO:0007165] GO:0001540; GO:0001666; GO:0005737; GO:0005886; GO:0005892; GO:0006816; GO:0006874; GO:0007165; GO:0008284; GO:0015464; GO:0015643; GO:0017081; GO:0022848; GO:0030424; GO:0030425; GO:0032720; GO:0035094; GO:0042166; GO:0042803; GO:0043204; GO:0043410; GO:0045211; GO:0045766; GO:0050890; GO:0051899; GO:0080164 18229 XR_003822978.2 0 13 11 2 14 NA NA NA NA NA NA 18230 XM_029358464.2 0 0 0 40 0 P54131 1.27e-65 Neuronal acetylcholine receptor subunit alpha-7 Bos taurus (Bovine) calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; cognition [GO:0050890]; ion transmembrane transport [GO:0034220]; negative regulation of tumor necrosis factor production [GO:0032720]; nervous system process [GO:0050877]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAPK cascade [GO:0043410]; regulation of membrane potential [GO:0042391]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271] GO:0001540; GO:0001666; GO:0005231; GO:0005886; GO:0005892; GO:0006816; GO:0006874; GO:0007165; GO:0007268; GO:0007271; GO:0008284; GO:0015464; GO:0015643; GO:0017081; GO:0022848; GO:0030594; GO:0032720; GO:0034220; GO:0035094; GO:0042166; GO:0042391; GO:0042803; GO:0043005; GO:0043410; GO:0045202; GO:0045211; GO:0045766; GO:0050877; GO:0050890; GO:1904315 18231 XM_044326723.1 2 16 7 1 9 NA NA NA NA NA NA 18232 XM_029346207.2 24 37 16 48 39 Q10717 8.9e-76 Cysteine proteinase 2 (EC 3.4.22.-) Zea mays (Maize) aging [GO:0007568]; proteolysis involved in protein catabolic process [GO:0051603] GO:0004197; GO:0005615; GO:0005764; GO:0007568; GO:0051603 18233 XR_006396298.1 81 76 43 96 8 NA NA NA NA NA NA 18234 XM_044308815.1 0 41 282 130 482 Q8BLN6 0 Protein unc-80 homolog (mUNC-80) Mus musculus (Mouse) cation homeostasis [GO:0055080] GO:0005261; GO:0005886; GO:0030424; GO:0030425; GO:0034703; GO:0034706; GO:0055080 18235 XM_044308815.1 0 41 282 130 482 Q8BLN6 2.69e-41 Protein unc-80 homolog (mUNC-80) Mus musculus (Mouse) cation homeostasis [GO:0055080] GO:0005261; GO:0005886; GO:0030424; GO:0030425; GO:0034703; GO:0034706; GO:0055080 18236 XM_044308815.1 0 41 282 130 482 Q8BLN6 1.88e-29 Protein unc-80 homolog (mUNC-80) Mus musculus (Mouse) cation homeostasis [GO:0055080] GO:0005261; GO:0005886; GO:0030424; GO:0030425; GO:0034703; GO:0034706; GO:0055080 18237 XM_029358210.2 4 5 13 0 57 NA NA NA NA NA NA 18238 XM_029337715.2 2593 1860 1643 2690 2064 Q5ZMJ9 4.09e-45 Serine/arginine repetitive matrix protein 1 Gallus gallus (Chicken) mRNA processing [GO:0006397]; regulation of mRNA splicing, via spliceosome [GO:0048024]; RNA splicing [GO:0008380] GO:0005681; GO:0006397; GO:0008380; GO:0048024 18239 XM_029352307.2 1 255 1 1 115 NA NA NA NA NA NA 18240 XM_044309042.1 11 52 4 56 74 NA NA NA NA NA NA 18241 XM_044313637.1 129 0 38 0 139 NA NA NA NA NA NA 18242 XM_029333518.2 9 51 29 5 70 B8VIU6 1.69e-56 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 18243 XM_044321271.1 99 19 40 211 128 NA NA NA NA NA NA 18244 XM_044307071.1 9 46 0 2 5 NA NA NA NA NA NA 18245 XR_003825559.2 0 0 0 0 6 NA NA NA NA NA NA 18246 XM_044306805.1 734 460 242 416 374 NA NA NA NA NA NA 18247 XM_029343296.2 78 0 0 0 0 Q15329 7.23e-93 Transcription factor E2F5 (E2F-5) Homo sapiens (Human) cell projection organization [GO:0030030]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000785; GO:0000978; GO:0000981; GO:0001216; GO:0001650; GO:0003700; GO:0005654; GO:0005730; GO:0006357; GO:0030030; GO:0043231; GO:0046983; GO:0090575 18248 XM_029357052.2 601 703 239 308 359 Q8CGF6 2.3e-101 WD repeat-containing protein 47 (Neuronal enriched MAP interacting protein) (Nemitin) Mus musculus (Mouse) adult locomotory behavior [GO:0008344]; anterior commissure morphogenesis [GO:0021960]; autophagy [GO:0006914]; brain development [GO:0007420]; cerebral cortex development [GO:0021987]; cerebral cortex radial glia-guided migration [GO:0021801]; corpus callosum development [GO:0022038]; detection of hot stimulus involved in thermoception [GO:0120168]; locomotory behavior [GO:0007626]; microtubule cytoskeleton organization [GO:0000226]; motor behavior [GO:0061744]; negative regulation of microtubule depolymerization [GO:0007026]; neural precursor cell proliferation [GO:0061351]; neuron projection development [GO:0031175]; neuronal stem cell population maintenance [GO:0097150] GO:0000226; GO:0005737; GO:0005874; GO:0006914; GO:0007026; GO:0007420; GO:0007626; GO:0008344; GO:0021801; GO:0021960; GO:0021987; GO:0022038; GO:0030424; GO:0030425; GO:0030426; GO:0031175; GO:0043005; GO:0043025; GO:0044877; GO:0047485; GO:0061351; GO:0061744; GO:0097150; GO:0120168 18249 XM_029357052.2 601 703 239 308 359 Q8CGF6 1.24e-52 WD repeat-containing protein 47 (Neuronal enriched MAP interacting protein) (Nemitin) Mus musculus (Mouse) adult locomotory behavior [GO:0008344]; anterior commissure morphogenesis [GO:0021960]; autophagy [GO:0006914]; brain development [GO:0007420]; cerebral cortex development [GO:0021987]; cerebral cortex radial glia-guided migration [GO:0021801]; corpus callosum development [GO:0022038]; detection of hot stimulus involved in thermoception [GO:0120168]; locomotory behavior [GO:0007626]; microtubule cytoskeleton organization [GO:0000226]; motor behavior [GO:0061744]; negative regulation of microtubule depolymerization [GO:0007026]; neural precursor cell proliferation [GO:0061351]; neuron projection development [GO:0031175]; neuronal stem cell population maintenance [GO:0097150] GO:0000226; GO:0005737; GO:0005874; GO:0006914; GO:0007026; GO:0007420; GO:0007626; GO:0008344; GO:0021801; GO:0021960; GO:0021987; GO:0022038; GO:0030424; GO:0030425; GO:0030426; GO:0031175; GO:0043005; GO:0043025; GO:0044877; GO:0047485; GO:0061351; GO:0061744; GO:0097150; GO:0120168 18250 XM_044319251.1 0 323 0 274 1147 NA NA NA NA NA NA 18251 XR_006396647.1 54 107 55 45 91 NA NA NA NA NA NA 18252 XM_029341672.2 48 20 87 0 36 F1NWE3 5.98e-143 Receptor-type tyrosine-protein phosphatase S (R-PTP-S) (EC 3.1.3.48) (Chick receptor tyrosine phosphatase alpha) (CRYP alpha) (CRYPalpha) Gallus gallus (Chicken) negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; synaptic membrane adhesion [GO:0099560] GO:0004725; GO:0005886; GO:0006470; GO:0008201; GO:0030424; GO:0030426; GO:0030517; GO:0030672; GO:0035335; GO:0042803; GO:0043204; GO:0043395; GO:0048671; GO:0048681; GO:0061000; GO:0098839; GO:0099560 18253 XM_029358145.2 0 0 216 96 54 NA NA NA NA NA NA 18254 XM_044316336.1 123 32 47 40 127 NA NA NA NA NA NA 18255 XM_029357538.2 524 605 257 593 387 Q9WV04 0 Kinesin-like protein KIF9 Mus musculus (Mouse) extracellular matrix disassembly [GO:0022617]; microtubule-based movement [GO:0007018]; organelle disassembly [GO:1903008]; regulation of flagellated sperm motility [GO:1901317]; regulation of podosome assembly [GO:0071801] GO:0002102; GO:0003777; GO:0005524; GO:0005829; GO:0005871; GO:0005874; GO:0007018; GO:0008017; GO:0016887; GO:0022617; GO:0031982; GO:0036126; GO:0042802; GO:0071801; GO:1901317; GO:1903008 18256 XM_029349813.2 2759 2583 1950 2440 1893 A7S1L6 5.5e-175 GDP-fucose transporter 1 (Solute carrier family 35 member C1 homolog) Nematostella vectensis (Starlet sea anemone) carbohydrate transport [GO:0008643]; GDP-fucose import into Golgi lumen [GO:0036085]; protein O-linked fucosylation [GO:0036066] GO:0000139; GO:0005457; GO:0005794; GO:0008643; GO:0015297; GO:0036066; GO:0036085 18257 XM_029332005.2 756 789 513 989 1212 Q9BUQ8 0 Probable ATP-dependent RNA helicase DDX23 (EC 3.6.4.13) (100 kDa U5 snRNP-specific protein) (DEAD box protein 23) (PRP28 homolog) (U5-100kD) Homo sapiens (Human) cis assembly of pre-catalytic spliceosome [GO:0000354]; mRNA splicing, via spliceosome [GO:0000398]; R-loop processing [GO:0062176]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375] GO:0000354; GO:0000375; GO:0000398; GO:0000785; GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005654; GO:0005682; GO:0005730; GO:0008380; GO:0016887; GO:0046540; GO:0062176; GO:0070062; GO:0071013 18258 XR_006397205.1 10 18 3 2 24 B8VIU6 1.98e-30 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 18259 XM_029331126.2 51 17 5 39 0 Q9CPW0 8.13e-40 Contactin-associated protein-like 2 (Cell recognition molecule Caspr2) Mus musculus (Mouse) action potential initiation [GO:0099610]; adult behavior [GO:0030534]; associative learning [GO:0008306]; axonogenesis [GO:0007409]; behavioral response to pain [GO:0048266]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell population proliferation [GO:0008283]; central nervous system myelination [GO:0022010]; cerebellar Purkinje cell layer morphogenesis [GO:0021692]; cerebellum development [GO:0021549]; chemical synaptic transmission [GO:0007268]; circadian sleep/wake cycle [GO:0042745]; clustering of voltage-gated potassium channels [GO:0045163]; dendrite arborization [GO:0140059]; dendritic spine development [GO:0060996]; dendritic spine maintenance [GO:0097062]; dendritic spine organization [GO:0097061]; embryonic brain development [GO:1990403]; ERK1 and ERK2 cascade [GO:0070371]; excitatory chemical synaptic transmission [GO:0098976]; excitatory postsynaptic potential [GO:0060079]; excitatory synapse assembly [GO:1904861]; fat cell differentiation [GO:0045444]; gene expression [GO:0010467]; glial cell proliferation [GO:0014009]; glutamatergic neuron differentiation [GO:1905962]; grooming behavior [GO:0007625]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; inhibitory chemical synaptic transmission [GO:0098977]; inhibitory synapse assembly [GO:1904862]; intracellular signal transduction [GO:0035556]; learning [GO:0007612]; limbic system development [GO:0021761]; locomotor rhythm [GO:0045475]; locomotory behavior [GO:0007626]; maintenance of synapse structure [GO:0099558]; mitochondrion organization [GO:0007005]; motor behavior [GO:0061744]; multicellular organism growth [GO:0035264]; myelination [GO:0042552]; negative regulation of neuronal action potential [GO:1904456]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; neural precursor cell proliferation [GO:0061351]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process [GO:0050905]; neuromuscular process controlling posture [GO:0050884]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuron recognition [GO:0008038]; neuronal action potential [GO:0019228]; positive regulation of gap junction assembly [GO:1903598]; positive regulation of neuronal action potential [GO:1904457]; postsynaptic density organization [GO:0097106]; protein kinase B signaling [GO:0043491]; protein localization [GO:0008104]; protein localization to juxtaparanode region of axon [GO:0071205]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; response to dietary excess [GO:0002021]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to interleukin-17 [GO:0097396]; response to light intensity [GO:0009642]; response to mechanical stimulus [GO:0009612]; response to metformin [GO:1901558]; response to odorant [GO:1990834]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; rhythmic behavior [GO:0007622]; social behavior [GO:0035176]; TOR signaling [GO:0031929]; transmission of nerve impulse [GO:0019226]; vocal learning [GO:0042297]; vocalization behavior [GO:0071625]; walking behavior [GO:0090659] GO:0000902; GO:0001701; GO:0002021; GO:0005769; GO:0005794; GO:0006954; GO:0007005; GO:0007155; GO:0007268; GO:0007409; GO:0007612; GO:0007622; GO:0007625; GO:0007626; GO:0008038; GO:0008076; GO:0008104; GO:0008283; GO:0008306; GO:0009408; GO:0009410; GO:0009612; GO:0009642; GO:0009725; GO:0009986; GO:0010033; GO:0010467; GO:0014009; GO:0016020; GO:0019226; GO:0019228; GO:0019899; GO:0021549; GO:0021692; GO:0021761; GO:0022010; GO:0030165; GO:0030424; GO:0030425; GO:0030534; GO:0030673; GO:0031175; GO:0031929; GO:0032229; GO:0033010; GO:0035176; GO:0035264; GO:0035556; GO:0042297; GO:0042552; GO:0042734; GO:0042745; GO:0043005; GO:0043025; GO:0043194; GO:0043491; GO:0044224; GO:0044309; GO:0044853; GO:0045163; GO:0045202; GO:0045444; GO:0045475; GO:0048265; GO:0048266; GO:0048787; GO:0048812; GO:0050884; GO:0050905; GO:0060076; GO:0060079; GO:0060996; GO:0061351; GO:0061744; GO:0070371; GO:0071205; GO:0071625; GO:0090659; GO:0097061; GO:0097062; GO:0097106; GO:0097396; GO:0098529; GO:0098793; GO:0098794; GO:0098976; GO:0098977; GO:0098978; GO:0098982; GO:0099072; GO:0099558; GO:0099610; GO:0140059; GO:0150048; GO:1901558; GO:1903598; GO:1904456; GO:1904457; GO:1904861; GO:1904862; GO:1905962; GO:1990403; GO:1990834 18260 XM_029352751.2 1079 530 486 591 572 A7SG48 1.29e-39 UPF0728 protein v1g117062 Nematostella vectensis (Starlet sea anemone) NA NA 18261 XM_029351153.2 118 85 109 546 109 Q80T21 2.08e-117 ADAMTS-like protein 4 (ADAMTSL-4) (Thrombospondin repeat-containing protein 1) Mus musculus (Mouse) apoptotic process [GO:0006915]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; pigment cell development [GO:0070285]; positive regulation of apoptotic process [GO:0043065] GO:0002020; GO:0002064; GO:0005576; GO:0005614; GO:0006915; GO:0030198; GO:0031012; GO:0042802; GO:0043065; GO:0070285 18262 XM_044323022.1 3264 659 308 3685 2396 P02466 4.61e-46 Collagen alpha-2(I) chain (Alpha-2 type I collagen) Rattus norvegicus (Rat) blood vessel development [GO:0001568]; bone mineralization [GO:0030282]; cellular response to amino acid stimulus [GO:0071230]; cellular response to organic substance [GO:0071310]; cellular response to retinoic acid [GO:0071300]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; extracellular matrix assembly [GO:0085029]; extracellular matrix organization [GO:0030198]; protein heterotrimerization [GO:0070208]; regulation of blood pressure [GO:0008217]; response to norepinephrine [GO:0071873]; Rho protein signal transduction [GO:0007266]; skeletal system development [GO:0001501]; skin morphogenesis [GO:0043589]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001501; GO:0001568; GO:0002020; GO:0005201; GO:0005576; GO:0005581; GO:0005584; GO:0005615; GO:0007179; GO:0007266; GO:0008217; GO:0030198; GO:0030199; GO:0030282; GO:0030674; GO:0031012; GO:0032963; GO:0042802; GO:0043589; GO:0046332; GO:0046872; GO:0048407; GO:0062023; GO:0070208; GO:0071230; GO:0071300; GO:0071310; GO:0071873; GO:0085029; GO:0097067 18263 XR_006394434.1 153 68 2 96 21 NA NA NA NA NA NA 18264 XM_044306854.1 4 7 0 0 0 NA NA NA NA NA NA 18265 XM_044316022.1 45 287 45 173 78 NA NA NA NA NA NA 18266 XM_044321186.1 1100 1854 706 683 2239 NA NA NA NA NA NA 18267 XM_029351873.2 39 0 25 4 2 Q56X76 7.01e-59 DEAD-box ATP-dependent RNA helicase 39 (EC 3.6.4.13) Arabidopsis thaliana (Mouse-ear cress) chloroplast rRNA processing [GO:1901259]; mitochondrial large ribosomal subunit assembly [GO:1902775]; ribulose bisphosphate carboxylase complex assembly [GO:0110102] GO:0003724; GO:0003729; GO:0005524; GO:0005739; GO:0009507; GO:0016887; GO:0070180; GO:0110102; GO:1901259; GO:1902775 18268 XM_029349319.2 908 413 518 819 794 NA NA NA NA NA NA 18269 XM_029325360.2 9 0 0 0 0 NA NA NA NA NA NA 18270 XM_029346527.2 325 286 29 21 0 Q9I8C7 2.66e-93 Neuronal acetylcholine receptor subunit alpha-10 (Alpha 10 nAChR) (Nicotinic acetylcholine receptor subunit alpha-10) (NACHR alpha-10) Gallus gallus (Chicken) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; response to auditory stimulus [GO:0010996]; signal transduction [GO:0007165] GO:0004888; GO:0005231; GO:0005262; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0010996; GO:0022848; GO:0030594; GO:0034220; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051899; GO:1904315 18271 XM_044310535.1 297 223 31 38 179 NA NA NA NA NA NA 18272 XM_044316843.1 0 0 0 0 19 NA NA NA NA NA NA 18273 XM_044317877.1 1312 546 517 582 884 B0JZ65 3.92e-55 Leucine-rich repeat and WD repeat-containing protein 1 (ORC-associated protein) (ORCA) (Origin recognition complex-associated protein) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) chromatin organization [GO:0006325]; DNA replication [GO:0006260]; establishment of protein localization to chromatin [GO:0071169] GO:0000776; GO:0000781; GO:0003682; GO:0005634; GO:0005664; GO:0005721; GO:0005737; GO:0005815; GO:0006260; GO:0006325; GO:0008327; GO:0035064; GO:0071169 18274 XM_044312994.1 0 39 240 0 304 Q60997 7.39e-34 Deleted in malignant brain tumors 1 protein (Apactin) (CRP-ductin) (Glycoprotein 300) (gp300) (Hensin) (Mucin-like glycoprotein) (Muclin) (Vomeroglandin) (p80) Mus musculus (Mouse) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blastocyst development [GO:0001824]; columnar/cuboidal epithelial cell differentiation [GO:0002065]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterial lipoprotein [GO:0042494]; induction of bacterial agglutination [GO:0043152]; inner cell mass cell proliferation [GO:0001833]; positive regulation of epithelial cell differentiation [GO:0030858]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617] GO:0001530; GO:0001824; GO:0001833; GO:0002065; GO:0003677; GO:0005044; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0009617; GO:0015031; GO:0019898; GO:0030658; GO:0030670; GO:0030858; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0050829; GO:0050830; GO:0050840; GO:0061844; GO:0062023; GO:0070891; GO:1904399 18275 XM_044312994.1 0 39 240 0 304 Q60997 1.22e-29 Deleted in malignant brain tumors 1 protein (Apactin) (CRP-ductin) (Glycoprotein 300) (gp300) (Hensin) (Mucin-like glycoprotein) (Muclin) (Vomeroglandin) (p80) Mus musculus (Mouse) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blastocyst development [GO:0001824]; columnar/cuboidal epithelial cell differentiation [GO:0002065]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterial lipoprotein [GO:0042494]; induction of bacterial agglutination [GO:0043152]; inner cell mass cell proliferation [GO:0001833]; positive regulation of epithelial cell differentiation [GO:0030858]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617] GO:0001530; GO:0001824; GO:0001833; GO:0002065; GO:0003677; GO:0005044; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0009617; GO:0015031; GO:0019898; GO:0030658; GO:0030670; GO:0030858; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0050829; GO:0050830; GO:0050840; GO:0061844; GO:0062023; GO:0070891; GO:1904399 18276 XM_044312994.1 0 39 240 0 304 Q60997 2.56e-28 Deleted in malignant brain tumors 1 protein (Apactin) (CRP-ductin) (Glycoprotein 300) (gp300) (Hensin) (Mucin-like glycoprotein) (Muclin) (Vomeroglandin) (p80) Mus musculus (Mouse) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blastocyst development [GO:0001824]; columnar/cuboidal epithelial cell differentiation [GO:0002065]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterial lipoprotein [GO:0042494]; induction of bacterial agglutination [GO:0043152]; inner cell mass cell proliferation [GO:0001833]; positive regulation of epithelial cell differentiation [GO:0030858]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617] GO:0001530; GO:0001824; GO:0001833; GO:0002065; GO:0003677; GO:0005044; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0009617; GO:0015031; GO:0019898; GO:0030658; GO:0030670; GO:0030858; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0050829; GO:0050830; GO:0050840; GO:0061844; GO:0062023; GO:0070891; GO:1904399 18277 XM_044316867.1 111 139 13 145 69 Q7ZWG6 2.59e-44 Proton-coupled folate transporter (Solute carrier family 46 member 1) Danio rerio (Zebrafish) (Brachydanio rerio) transmembrane transport [GO:0055085] GO:0005542; GO:0005768; GO:0005886; GO:0010008; GO:0015293; GO:0015350; GO:0016020; GO:0016323; GO:0016324; GO:0022857; GO:0055085 18278 XM_029332072.2 0 148 0 193 0 Q7T3E6 2.29e-52 Polycomb complex protein BMI-1-B (Polycomb group RING finger protein 4-B) Danio rerio (Zebrafish) (Brachydanio rerio) cerebellum development [GO:0021549]; histone H2A-K119 monoubiquitination [GO:0036353]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of transcription by RNA polymerase II [GO:0000122] GO:0000122; GO:0021549; GO:0031519; GO:0035102; GO:0036353; GO:0045814; GO:0046872; GO:1990841 18279 XM_029350050.2 0 0 0 0 86 NA NA NA NA NA NA 18280 XR_006391500.1 0 8 7 4 6 NA NA NA NA NA NA 18281 XM_029338456.2 1961 1499 1110 1357 872 Q7K556 1.87e-156 TRPL translocation defect protein 14 Drosophila melanogaster (Fruit fly) photoreceptor cell maintenance [GO:0045494]; protein transport [GO:0015031] GO:0005525; GO:0005829; GO:0015031; GO:0035091; GO:0045494; GO:0070300 18282 XM_044318706.1 22 19 22 57 22 NA NA NA NA NA NA 18283 XM_029355757.2 300 333 189 136 149 Q6DRM0 2.72e-21 Guided entry of tail-anchored proteins factor 1 (Tail-anchored protein insertion receptor WRB) (Tryptophan-rich basic protein) Danio rerio (Zebrafish) (Brachydanio rerio) heart development [GO:0007507]; response to auditory stimulus [GO:0010996]; retina development in camera-type eye [GO:0060041]; sensory perception of sound [GO:0007605]; startle response [GO:0001964]; tail-anchored membrane protein insertion into ER membrane [GO:0071816] GO:0001964; GO:0005783; GO:0005789; GO:0007507; GO:0007605; GO:0010996; GO:0060041; GO:0071816 18284 XM_029337882.2 307 245 226 339 183 Q8IYJ2 4.42e-24 Uncharacterized protein C10orf67, mitochondrial Homo sapiens (Human) NA GO:0005739 18285 XM_029337316.2 4983 4177 1887 4462 3845 P23004 2.78e-89 Cytochrome b-c1 complex subunit 2, mitochondrial (Complex III subunit 2) (Core protein II) (Ubiquinol-cytochrome-c reductase complex core protein 2) Bos taurus (Bovine) proteolysis [GO:0006508] GO:0004222; GO:0005739; GO:0005743; GO:0006508; GO:0046872; GO:0070469 18286 XM_044315061.1 0 27 58 0 0 NA NA NA NA NA NA 18287 XR_006394819.1 0 0 0 10 0 NA NA NA NA NA NA 18288 XM_029342864.2 203 134 179 284 339 NA NA NA NA NA NA 18289 XM_044309962.1 1 0 0 6 0 NA NA NA NA NA NA 18290 XM_029336981.2 1298 1777 1071 855 580 NA NA NA NA NA NA 18291 XM_029350322.2 72 11 0 92 35 NA NA NA NA NA NA 18292 XM_044318237.1 151 56 53 157 115 E7FAM5 3.38e-80 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 18293 XM_044314400.1 328 60 104 293 232 Q96AY4 5.3e-128 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18294 XM_044314400.1 328 60 104 293 232 Q96AY4 6.58e-116 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18295 XM_044314400.1 328 60 104 293 232 Q96AY4 6.58e-115 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18296 XM_044314400.1 328 60 104 293 232 Q96AY4 2.33e-113 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18297 XM_044314400.1 328 60 104 293 232 Q96AY4 5.64e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18298 XM_044325363.1 535 321 208 315 484 NA NA NA NA NA NA 18299 XR_006395690.1 3332 2353 2202 3454 2292 NA NA NA NA NA NA 18300 XM_044313244.1 314 105 172 93 405 NA NA NA NA NA NA 18301 XM_029353825.2 25 38 18 26 10 Q766D5 3.82e-75 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Mus musculus (Mouse) chondroitin sulfate biosynthetic process [GO:0030206] GO:0008376; GO:0030206; GO:0032580; GO:0033842; GO:0047238 18302 XM_029356963.2 2940 4580 2300 2988 2688 Q6NZW8 1.06e-117 ADP-ribosylation factor-like protein 8B-A Danio rerio (Zebrafish) (Brachydanio rerio) anterograde axonal transport [GO:0008089]; autophagosome-lysosome fusion [GO:0061909]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; late endosome to lysosome transport [GO:1902774]; lysosome localization [GO:0032418]; protein transport [GO:0015031] GO:0003924; GO:0005525; GO:0005764; GO:0005765; GO:0005819; GO:0007059; GO:0008089; GO:0015031; GO:0031902; GO:0032418; GO:0051301; GO:0061909; GO:1902774; GO:1904115 18303 XM_029324740.2 637 444 486 621 651 Q91437 0 CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)] Squalus acanthias (Spiny dogfish) 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; glutamine metabolic process [GO:0006541] GO:0004070; GO:0004088; GO:0004151; GO:0005524; GO:0005634; GO:0005737; GO:0006207; GO:0006541; GO:0008270; GO:0016597; GO:0044205 18304 XM_029333823.2 229 195 124 182 180 NA NA NA NA NA NA 18305 XM_044322814.1 0 24 275 0 24 D3ZTD8 5.92e-77 Semaphorin-5A (Semaphorin-F) (Sema F) Rattus norvegicus (Rat) axon extension [GO:0048675]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; cell chemotaxis [GO:0060326]; detection of light stimulus involved in visual perception [GO:0050908]; diencephalon development [GO:0021536]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of cell adhesion [GO:0007162]; negative regulation of endothelial cell apoptotic process [GO:2000352]; neural crest cell migration [GO:0001755]; neuron projection extension [GO:1990138]; neuron projection guidance [GO:0097485]; positive chemotaxis [GO:0050918]; positive regulation of actin filament depolymerization [GO:0030836]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein kinase B signaling [GO:0051897]; semaphorin-plexin signaling pathway [GO:0071526]; signal clustering [GO:1990256] GO:0001569; GO:0001755; GO:0001938; GO:0002043; GO:0007162; GO:0007411; GO:0007413; GO:0008046; GO:0016020; GO:0021536; GO:0030215; GO:0030335; GO:0030836; GO:0035373; GO:0043395; GO:0045499; GO:0045545; GO:0045766; GO:0048675; GO:0048754; GO:0048842; GO:0048843; GO:0050908; GO:0050918; GO:0051897; GO:0060326; GO:0071526; GO:0090263; GO:0097485; GO:1990138; GO:1990256; GO:2000352; GO:2001028 18306 XM_029356837.2 29 3 24 30 27 NA NA NA NA NA NA 18307 XM_029352314.2 1118 1225 560 1164 1058 NA NA NA NA NA NA 18308 XR_006393273.1 4 41 20 24 26 NA NA NA NA NA NA 18309 XM_044323784.1 24 17 14 14 68 NA NA NA NA NA NA 18310 XM_044310581.1 16 0 1 0 3 P0CT40 3.3e-76 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 18311 XM_029323484.2 748 371 431 656 851 P0C6B8 5.66e-23 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 18312 XM_044321338.1 11 27 208 32 381 P46023 2.04e-101 G-protein coupled receptor GRL101 Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004930; GO:0005886 18313 XR_003825508.2 0 1 3 6 5 NA NA NA NA NA NA 18314 XR_006398167.1 0 13 8 8 19 NA NA NA NA NA NA 18315 XM_029353822.2 772 464 386 464 770 NA NA NA NA NA NA 18316 XM_029329966.2 28 5 10 12 24 NA NA NA NA NA NA 18317 XM_029337701.2 1900 1295 630 1191 597 Q8VZI2 8.38e-75 DUF21 domain-containing protein At4g33700 (CBS domain-containing protein CBSDUF6) Arabidopsis thaliana (Mouse-ear cress) magnesium ion homeostasis [GO:0010960] GO:0005886; GO:0010960; GO:0043231 18318 XR_006392610.1 6 0 0 14 2 NA NA NA NA NA NA 18319 XR_006391703.1 0 0 6 5 0 Q9UBR1 0 Beta-ureidopropionase (EC 3.5.1.6) (BUP-1) (Beta-alanine synthase) (N-carbamoyl-beta-alanine amidohydrolase) Homo sapiens (Human) beta-alanine biosynthetic process via 3-ureidopropionate [GO:0033396]; CMP catabolic process [GO:0006248]; dCMP catabolic process [GO:0006249]; dUMP catabolic process [GO:0046079]; in utero embryonic development [GO:0001701]; liver development [GO:0001889]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; pyrimidine nucleoside catabolic process [GO:0046135]; UMP catabolic process [GO:0046050] GO:0001701; GO:0001889; GO:0003837; GO:0005829; GO:0006248; GO:0006249; GO:0016811; GO:0033396; GO:0042803; GO:0046050; GO:0046079; GO:0046135; GO:0051260; GO:0051289; GO:0070062 18320 XR_006397072.1 226 155 138 134 319 NA NA NA NA NA NA 18321 XM_029338154.2 1079 605 626 951 893 Q3UY96 0 Cilia- and flagella-associated protein 74 Mus musculus (Mouse) axoneme assembly [GO:0035082] GO:0005930; GO:0035082 18322 XM_044312237.1 0 0 11 6 27 NA NA NA NA NA NA 18323 XM_029349956.2 1114 971 493 1111 1281 Q55DA0 5.08e-39 ABC transporter G family member 22 (ABC transporter ABCG.22) Dictyostelium discoideum (Social amoeba) aggregation involved in sorocarp development [GO:0031152]; cell motility [GO:0048870]; sorocarp morphogenesis [GO:0031288]; transmembrane transport [GO:0055085] GO:0005524; GO:0016020; GO:0016887; GO:0031152; GO:0031288; GO:0042626; GO:0048870; GO:0055085; GO:0140359 18324 XM_029325132.2 43 54 21 35 14 A7S8T5 1.67e-174 Coiled-coil domain-containing protein 42 homolog Nematostella vectensis (Starlet sea anemone) NA NA 18325 XR_006392466.1 10 19 6 19 0 NA NA NA NA NA NA 18326 XM_044316816.1 19 8 0 31 2 NA NA NA NA NA NA 18327 XM_044312885.1 48 16 4 145 49 NA NA NA NA NA NA 18328 XM_029343312.2 0 0 0 8 14 Q8BFQ2 1.73e-29 Transmembrane protein 229B Mus musculus (Mouse) macrophage activation [GO:0042116]; response to bacterium [GO:0009617] GO:0009617; GO:0016020; GO:0042116 18329 XM_044317804.1 145 109 94 337 259 O95294 0 RasGAP-activating-like protein 1 (RAS protein activator like 1) (Ras GTPase-activating-like protein) Homo sapiens (Human) cell differentiation [GO:0030154]; cellular response to calcium ion [GO:0071277]; intracellular signal transduction [GO:0035556]; negative regulation of Ras protein signal transduction [GO:0046580]; positive regulation of dendrite extension [GO:1903861]; regulation of GTPase activity [GO:0043087]; signal transduction [GO:0007165] GO:0005096; GO:0005543; GO:0005829; GO:0007165; GO:0030154; GO:0035556; GO:0043087; GO:0046580; GO:0046872; GO:0071277; GO:1903861 18330 XM_044308586.1 447 197 198 152 279 Q14678 1.88e-53 KN motif and ankyrin repeat domain-containing protein 1 (Ankyrin repeat domain-containing protein 15) (Kidney ankyrin repeat-containing protein) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cell population proliferation [GO:0008283]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of cell migration [GO:0030336]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lamellipodium morphogenesis [GO:2000393]; negative regulation of neuron projection development [GO:0010977]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of ruffle assembly [GO:1900028]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025]; podocyte cell migration [GO:0090521]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Wnt signaling pathway [GO:0030177]; positive regulation of wound healing [GO:0090303]; regulation of establishment of cell polarity [GO:2000114]; regulation of Rho protein signal transduction [GO:0035023] GO:0005634; GO:0005737; GO:0005856; GO:0005886; GO:0008013; GO:0008283; GO:0010977; GO:0030036; GO:0030177; GO:0030336; GO:0030837; GO:0032587; GO:0035023; GO:0035024; GO:0046627; GO:0090263; GO:0090303; GO:0090521; GO:1900025; GO:1900028; GO:2000114; GO:2000393 18331 XM_029338148.2 258 302 0 172 43 Q8CBF3 0 Ephrin type-B receptor 1 (EC 2.7.10.1) Mus musculus (Mouse) angiogenesis [GO:0001525]; axon guidance [GO:0007411]; camera-type eye morphogenesis [GO:0048593]; cell chemotaxis [GO:0060326]; cell-substrate adhesion [GO:0031589]; central nervous system projection neuron axonogenesis [GO:0021952]; cranial nerve development [GO:0021545]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; ephrin receptor signaling pathway [GO:0048013]; establishment of cell polarity [GO:0030010]; hindbrain tangential cell migration [GO:0021934]; immunological synapse formation [GO:0001771]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of satellite cell differentiation [GO:1902725]; negative regulation of skeletal muscle satellite cell proliferation [GO:1902723]; neural precursor cell proliferation [GO:0061351]; neurogenesis [GO:0022008]; optic nerve morphogenesis [GO:0021631]; positive regulation of kinase activity [GO:0033674]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of neuron death [GO:1901214]; retinal ganglion cell axon guidance [GO:0031290]; skeletal muscle satellite cell activation [GO:0014719]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0001525; GO:0001771; GO:0004713; GO:0004714; GO:0005005; GO:0005524; GO:0005737; GO:0005783; GO:0005829; GO:0005886; GO:0007169; GO:0007411; GO:0008046; GO:0014719; GO:0016020; GO:0021545; GO:0021631; GO:0021934; GO:0021952; GO:0022008; GO:0030010; GO:0030424; GO:0030425; GO:0031290; GO:0031589; GO:0031901; GO:0032433; GO:0033674; GO:0043005; GO:0043235; GO:0044877; GO:0045121; GO:0046328; GO:0046777; GO:0048013; GO:0048593; GO:0050804; GO:0050965; GO:0051965; GO:0060326; GO:0060996; GO:0060997; GO:0061351; GO:0070372; GO:0098978; GO:1901214; GO:1902723; GO:1902725 18332 XM_044317115.1 0 0 9 0 5 NA NA NA NA NA NA 18333 XR_006396863.1 561 138 151 231 160 Q04786 6.82e-146 Beta-hexosaminidase (EC 3.2.1.52) (Beta-N-acetylhexosaminidase) (Chitobiase) (N-acetyl-beta-glucosaminidase) Vibrio vulnificus chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272] GO:0000272; GO:0004563; GO:0006032; GO:0030247; GO:0102148 18334 XR_006396863.1 561 138 151 231 160 Q04786 6.82e-146 Beta-hexosaminidase (EC 3.2.1.52) (Beta-N-acetylhexosaminidase) (Chitobiase) (N-acetyl-beta-glucosaminidase) Vibrio vulnificus chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272] GO:0000272; GO:0004563; GO:0006032; GO:0030247; GO:0102148 18335 XM_044328147.1 317 111 150 451 847 O88974 6.47e-76 Histone-lysine N-methyltransferase SETDB1 (EC 2.1.1.366) (ERG-associated protein with SET domain) (ESET) (SET domain bifurcated 1) Mus musculus (Mouse) bone development [GO:0060348]; heterochromatin organization [GO:0070828]; histone H3-K9 methylation [GO:0051567]; inner cell mass cell proliferation [GO:0001833]; negative regulation of gene expression [GO:0010629]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA methylation-dependent heterochromatin formation [GO:0090309]; Ras protein signal transduction [GO:0007265] GO:0000122; GO:0001833; GO:0003677; GO:0003682; GO:0005634; GO:0005654; GO:0005694; GO:0005737; GO:0007265; GO:0008270; GO:0010629; GO:0018024; GO:0043231; GO:0045869; GO:0046974; GO:0051567; GO:0060348; GO:0070828; GO:0090309; GO:0140947; GO:0140948; GO:1990841 18336 XM_044328147.1 317 111 150 451 847 O88974 2.05e-44 Histone-lysine N-methyltransferase SETDB1 (EC 2.1.1.366) (ERG-associated protein with SET domain) (ESET) (SET domain bifurcated 1) Mus musculus (Mouse) bone development [GO:0060348]; heterochromatin organization [GO:0070828]; histone H3-K9 methylation [GO:0051567]; inner cell mass cell proliferation [GO:0001833]; negative regulation of gene expression [GO:0010629]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA methylation-dependent heterochromatin formation [GO:0090309]; Ras protein signal transduction [GO:0007265] GO:0000122; GO:0001833; GO:0003677; GO:0003682; GO:0005634; GO:0005654; GO:0005694; GO:0005737; GO:0007265; GO:0008270; GO:0010629; GO:0018024; GO:0043231; GO:0045869; GO:0046974; GO:0051567; GO:0060348; GO:0070828; GO:0090309; GO:0140947; GO:0140948; GO:1990841 18337 XM_044328147.1 317 111 150 451 847 O88974 4.07e-39 Histone-lysine N-methyltransferase SETDB1 (EC 2.1.1.366) (ERG-associated protein with SET domain) (ESET) (SET domain bifurcated 1) Mus musculus (Mouse) bone development [GO:0060348]; heterochromatin organization [GO:0070828]; histone H3-K9 methylation [GO:0051567]; inner cell mass cell proliferation [GO:0001833]; negative regulation of gene expression [GO:0010629]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA methylation-dependent heterochromatin formation [GO:0090309]; Ras protein signal transduction [GO:0007265] GO:0000122; GO:0001833; GO:0003677; GO:0003682; GO:0005634; GO:0005654; GO:0005694; GO:0005737; GO:0007265; GO:0008270; GO:0010629; GO:0018024; GO:0043231; GO:0045869; GO:0046974; GO:0051567; GO:0060348; GO:0070828; GO:0090309; GO:0140947; GO:0140948; GO:1990841 18338 XM_029341160.2 0 10 0 0 0 NA NA NA NA NA NA 18339 XM_029333543.2 961 1012 719 1395 1053 Q8NBN7 8.99e-100 Retinol dehydrogenase 13 (EC 1.1.1.300) (Short chain dehydrogenase/reductase family 7C member 3) Homo sapiens (Human) eye photoreceptor cell development [GO:0042462]; response to high light intensity [GO:0009644]; retina layer formation [GO:0010842]; retinal metabolic process [GO:0042574] GO:0005743; GO:0009644; GO:0010842; GO:0042462; GO:0042574; GO:0052650 18340 XM_029334512.2 826 220 225 389 176 NA NA NA NA NA NA 18341 XM_029352558.2 31 61 16 61 9 Q28I29 1.4e-45 tRNA-uridine aminocarboxypropyltransferase 1 (EC 2.5.1.25) (DTW domain-containing protein 1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) tRNA modification [GO:0006400] GO:0005634; GO:0006400; GO:0016432 18342 XM_044313159.1 5 19 2 0 18 O02824 9.91e-32 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) Oryctolagus cuniculus (Rabbit) adult heart development [GO:0007512]; cell growth involved in cardiac muscle cell development [GO:0061049]; MAPK cascade [GO:0000165]; multicellular organism aging [GO:0010259]; negative regulation of autophagy [GO:0010507]; negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure [GO:0001985]; neuron-glial cell signaling [GO:0150099]; norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001994]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; pilomotor reflex [GO:0097195]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of the force of heart contraction by epinephrine-norepinephrine [GO:0001997]; regulation of cardiac muscle contraction [GO:0055117]; regulation of vasoconstriction [GO:0019229] GO:0000165; GO:0001985; GO:0001994; GO:0001996; GO:0001997; GO:0004937; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0005901; GO:0007200; GO:0007512; GO:0010259; GO:0010507; GO:0010613; GO:0019229; GO:0031965; GO:0043410; GO:0045987; GO:0046982; GO:0055117; GO:0061049; GO:0097195; GO:0150099; GO:1903997 18343 XM_044316585.1 436 196 275 397 410 NA NA NA NA NA NA 18344 XM_044329217.1 57 0 17 1 2 NA NA NA NA NA NA 18345 XR_006397258.1 8 60 12 15 24 NA NA NA NA NA NA 18346 XM_029329245.2 89 57 51 107 94 Q5R621 7.17e-131 Heparan sulfate 2-O-sulfotransferase 1 (2-O-sulfotransferase) (2OST) (EC 2.8.2.-) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) gene expression [GO:0010467]; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0015014]; heparin metabolic process [GO:0030202]; ureteric bud formation [GO:0060676] GO:0000139; GO:0004394; GO:0010467; GO:0015014; GO:0030202; GO:0060676 18347 XM_044328029.1 7 12 14 20 15 NA NA NA NA NA NA 18348 XM_044308020.1 7 13 5 11 16 Q9Y5Q9 5.29e-22 General transcription factor 3C polypeptide 3 (Transcription factor IIIC 102 kDa subunit) (TFIIIC 102 kDa subunit) (TFIIIC102) (Transcription factor IIIC subunit gamma) (TF3C-gamma) Homo sapiens (Human) 5S class rRNA transcription by RNA polymerase III [GO:0042791]; transcription by RNA polymerase III [GO:0006383]; tRNA transcription by RNA polymerase III [GO:0042797] GO:0000127; GO:0000995; GO:0003677; GO:0005654; GO:0005730; GO:0006383; GO:0031965; GO:0042791; GO:0042797 18349 XM_029329212.2 2664 2376 985 2949 2120 Q15059 2.19e-102 Bromodomain-containing protein 3 (RING3-like protein) Homo sapiens (Human) chromatin remodeling [GO:0006338]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000785; GO:0003682; GO:0005634; GO:0006338; GO:0006355; GO:0006357; GO:0070577 18350 XM_029329212.2 2664 2376 985 2949 2120 Q15059 2.67e-40 Bromodomain-containing protein 3 (RING3-like protein) Homo sapiens (Human) chromatin remodeling [GO:0006338]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000785; GO:0003682; GO:0005634; GO:0006338; GO:0006355; GO:0006357; GO:0070577 18351 XM_029329212.2 2664 2376 985 2949 2120 Q15059 4.75e-26 Bromodomain-containing protein 3 (RING3-like protein) Homo sapiens (Human) chromatin remodeling [GO:0006338]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000785; GO:0003682; GO:0005634; GO:0006338; GO:0006355; GO:0006357; GO:0070577 18352 XR_006393437.1 53 16 67 51 17 Q924C1 9.99e-55 Exportin-5 (Exp5) (Ran-binding protein 21) Mus musculus (Mouse) positive regulation of post-transcriptional gene silencing by RNA [GO:1900370]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; RNA export from nucleus [GO:0006405] GO:0000049; GO:0003723; GO:0003729; GO:0005049; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006405; GO:0006611; GO:0016442; GO:0031267; GO:0035281; GO:0042565; GO:0070883; GO:1900370; GO:1905172 18353 XM_029336968.2 445 418 363 303 437 Q54S12 1.16e-65 Transmembrane protein 104 homolog Dictyostelium discoideum (Social amoeba) NA GO:0016020 18354 XM_044321857.1 0 0 0 0 39 B3EWZ3 3.15e-72 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 18355 XM_044321857.1 0 0 0 0 39 B3EWZ3 1.72e-62 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 18356 XM_044321857.1 0 0 0 0 39 B3EWZ3 2.14e-40 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 18357 XM_029351606.2 21 21 6 6 40 NA NA NA NA NA NA 18358 XM_029336409.2 206 51 43 181 79 NA NA NA NA NA NA 18359 XM_044321630.1 207 0 123 66 88 P49914 2.14e-50 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) (5,10-methenyl-tetrahydrofolate synthetase) (MTHFS) (Methenyl-THF synthetase) Homo sapiens (Human) folic acid catabolic process [GO:0046657]; folic acid metabolic process [GO:0046655]; folic acid-containing compound biosynthetic process [GO:0009396]; formate metabolic process [GO:0015942]; glutamate metabolic process [GO:0006536]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653] GO:0005524; GO:0005542; GO:0005737; GO:0005739; GO:0005759; GO:0005829; GO:0006536; GO:0009396; GO:0015942; GO:0030272; GO:0035999; GO:0046653; GO:0046655; GO:0046657; GO:0046872 18360 XR_006394942.1 605 503 184 388 257 NA NA NA NA NA NA 18361 XM_044326454.1 18 6 13 5 42 NA NA NA NA NA NA 18362 XM_029340374.2 112 250 0 6 65 NA NA NA NA NA NA 18363 XR_006392744.1 26 5 11 22 17 NA NA NA NA NA NA 18364 XM_029333234.2 1698 478 822 1788 1337 Q92859 4.95e-127 Neogenin (Immunoglobulin superfamily DCC subclass member 2) Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; iron ion homeostasis [GO:0055072]; neuron migration [GO:0001764] GO:0001764; GO:0005654; GO:0005794; GO:0005886; GO:0007155; GO:0007411; GO:0009986; GO:0039706; GO:0044295; GO:0055072; GO:0098609; GO:0098797 18365 XM_029346118.2 2522 3208 1766 3554 1172 Q60452 0 General transcription and DNA repair factor IIH helicase subunit XPD (TFIIH subunit XPD) (EC 3.6.4.12) (CXPD) (DNA excision repair protein ERCC-2) (DNA repair protein complementing XP-D cells) (Xeroderma pigmentosum group D-complementing protein) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) apoptotic process [GO:0006915]; chromosome segregation [GO:0007059]; hair cell differentiation [GO:0035315]; nucleotide-excision repair [GO:0006289]; regulation of mitotic cell cycle phase transition [GO:1901990]; response to oxidative stress [GO:0006979]; transcription by RNA polymerase II [GO:0006366]; transcription-coupled nucleotide-excision repair [GO:0006283] GO:0003677; GO:0005524; GO:0005634; GO:0005675; GO:0005737; GO:0005819; GO:0006283; GO:0006289; GO:0006366; GO:0006915; GO:0006979; GO:0007059; GO:0008022; GO:0016887; GO:0035315; GO:0043139; GO:0046872; GO:0047485; GO:0051539; GO:0070516; GO:0071817; GO:1901990 18366 XM_044316406.1 0 24 3 5 28 NA NA NA NA NA NA 18367 XM_029353631.2 65 63 34 63 49 NA NA NA NA NA NA 18368 XM_029356799.2 153 368 95 222 396 Q13003 8.14e-81 Glutamate receptor ionotropic, kainate 3 (GluK3) (Excitatory amino acid receptor 5) (EAA5) (Glutamate receptor 7) (GluR-7) (GluR7) Homo sapiens (Human) G protein-coupled glutamate receptor signaling pathway [GO:0007216]; glutamate receptor signaling pathway [GO:0007215]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; regulation of membrane potential [GO:0042391]; synaptic transmission, glutamatergic [GO:0035249] GO:0001640; GO:0004970; GO:0005886; GO:0007215; GO:0007216; GO:0008066; GO:0015276; GO:0015277; GO:0030424; GO:0030425; GO:0032839; GO:0032983; GO:0035249; GO:0038023; GO:0042391; GO:0042734; GO:0043195; GO:0043204; GO:0045211; GO:0050804; GO:0051967; GO:0098978; GO:0099507; GO:1904315 18369 XM_029349976.2 44 31 41 18 8 NA NA NA NA NA NA 18370 XM_044325964.1 27 15 0 0 53 NA NA NA NA NA NA 18371 XM_044325159.1 7 1 1 0 11 NA NA NA NA NA NA 18372 XM_044326448.1 25 22 23 34 57 NA NA NA NA NA NA 18373 XM_044324714.1 13576 9672 7574 12294 6528 NA NA NA NA NA NA 18374 XM_044316820.1 123 0 2 79 4 NA NA NA NA NA NA 18375 XM_044327117.1 163 102 191 149 855 A4GTP4 1.39e-23 ETS domain-containing protein Elk-1 Rattus norvegicus (Rat) cell differentiation [GO:0030154]; cellular response to gamma radiation [GO:0071480]; cellular response to lipid [GO:0071396]; cellular response to testosterone stimulus [GO:0071394]; DNA-templated transcription [GO:0006351]; DNA-templated transcription elongation [GO:0006354]; gene expression [GO:0010467]; liver development [GO:0001889]; lung development [GO:0030324]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of neuron death [GO:1901216]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; response to fibroblast growth factor [GO:0071774]; response to light stimulus [GO:0009416] GO:0000976; GO:0000978; GO:0000981; GO:0001228; GO:0001889; GO:0003682; GO:0003690; GO:0003700; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0006351; GO:0006354; GO:0006355; GO:0006357; GO:0009416; GO:0010467; GO:0030154; GO:0030324; GO:0030374; GO:0030425; GO:0043025; GO:0043679; GO:0045893; GO:0045944; GO:0061629; GO:0071394; GO:0071396; GO:0071480; GO:0071774; GO:1901216; GO:1990837 18376 XM_029335632.2 8556 6864 5500 6402 4548 Q5R5U1 8.45e-106 Ras-related protein Rab-10 (EC 3.6.5.2) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) antigen processing and presentation [GO:0019882]; axonogenesis [GO:0007409]; cellular response to insulin stimulus [GO:0032869]; endoplasmic reticulum tubular network organization [GO:0071786]; endosomal transport [GO:0016197]; establishment of neuroblast polarity [GO:0045200]; establishment of protein localization to endoplasmic reticulum membrane [GO:0097051]; Golgi to plasma membrane protein transport [GO:0043001]; Golgi to plasma membrane transport [GO:0006893]; polarized epithelial cell differentiation [GO:0030859]; protein localization to basolateral plasma membrane [GO:1903361]; protein localization to plasma membrane [GO:0072659]; regulated exocytosis [GO:0045055]; vesicle-mediated transport [GO:0016192] GO:0003925; GO:0005525; GO:0005768; GO:0005789; GO:0005794; GO:0005802; GO:0005886; GO:0005929; GO:0006893; GO:0007409; GO:0016192; GO:0016197; GO:0019003; GO:0019882; GO:0030670; GO:0030859; GO:0031489; GO:0032593; GO:0032869; GO:0043001; GO:0045055; GO:0045200; GO:0048471; GO:0055037; GO:0055038; GO:0070382; GO:0071782; GO:0071786; GO:0072659; GO:0097051; GO:1903361 18377 XM_029344542.2 0 0 0 0 37 Q5M9N0 7.34e-29 Coiled-coil domain-containing protein 158 Homo sapiens (Human) NA NA 18378 XM_044314396.1 98 178 8 84 19 NA NA NA NA NA NA 18379 XM_029329680.2 436 263 225 214 338 NA NA NA NA NA NA 18380 XM_044317054.1 0 0 0 0 93 Q96D71 1.09e-25 RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1) Homo sapiens (Human) endocytosis [GO:0006897]; endosomal transport [GO:0016197] GO:0005509; GO:0005829; GO:0005886; GO:0005905; GO:0006897; GO:0016197; GO:0017124 18381 XM_029327291.2 543 702 445 426 574 D3ZTX0 2.81e-37 Transmembrane emp24 domain-containing protein 7 (p24 family protein gamma-3) (p24gamma3) (p27) Rattus norvegicus (Rat) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886] GO:0005783; GO:0005789; GO:0005793; GO:0005794; GO:0006886; GO:0006888; GO:0007030; GO:0012507; GO:0030134; GO:0030663; GO:0033116 18382 XM_029327224.2 1117 906 504 750 653 Q9UNL4 4.34e-96 Inhibitor of growth protein 4 (p29ING4) Homo sapiens (Human) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; DNA replication-dependent chromatin disassembly [GO:0140889]; histone H4-K12 acetylation [GO:0043983]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; histone modification [GO:0016570]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of growth [GO:0045926]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:1902164]; protein acetylation [GO:0006473]; regulation of cell cycle [GO:0051726]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cell growth [GO:0001558]; regulation of DNA biosynthetic process [GO:2000278]; regulation of DNA-templated transcription [GO:0006355] GO:0000123; GO:0001558; GO:0003676; GO:0003713; GO:0005634; GO:0005654; GO:0005829; GO:0006355; GO:0006473; GO:0006915; GO:0007049; GO:0008285; GO:0016570; GO:0035064; GO:0043065; GO:0043981; GO:0043982; GO:0043983; GO:0045111; GO:0045892; GO:0045926; GO:0046872; GO:0051726; GO:0140889; GO:1902164; GO:1902749; GO:2000278 18383 XM_044324908.1 156 333 0 74 344 Q9UQ26 2.52e-63 Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2) (Rab-3-interacting protein 3) Homo sapiens (Human) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-ion regulated exocytosis [GO:0017156]; cell differentiation [GO:0030154]; insulin secretion [GO:0030073]; intracellular protein transport [GO:0006886]; positive regulation of dendrite extension [GO:1903861]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of synaptic transmission [GO:0050806]; regulation of exocytosis [GO:0017157]; regulation of membrane potential [GO:0042391]; regulation of synaptic plasticity [GO:0048167]; spontaneous neurotransmitter secretion [GO:0061669] GO:0006886; GO:0007188; GO:0017156; GO:0017157; GO:0030073; GO:0030154; GO:0031267; GO:0042391; GO:0042734; GO:0042995; GO:0044325; GO:0046872; GO:0048167; GO:0048786; GO:0048788; GO:0048791; GO:0050806; GO:0061669; GO:0070062; GO:0097151; GO:1903861; GO:2000463 18384 XM_044324908.1 156 333 0 74 344 Q9UQ26 1.58e-30 Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2) (Rab-3-interacting protein 3) Homo sapiens (Human) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-ion regulated exocytosis [GO:0017156]; cell differentiation [GO:0030154]; insulin secretion [GO:0030073]; intracellular protein transport [GO:0006886]; positive regulation of dendrite extension [GO:1903861]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of synaptic transmission [GO:0050806]; regulation of exocytosis [GO:0017157]; regulation of membrane potential [GO:0042391]; regulation of synaptic plasticity [GO:0048167]; spontaneous neurotransmitter secretion [GO:0061669] GO:0006886; GO:0007188; GO:0017156; GO:0017157; GO:0030073; GO:0030154; GO:0031267; GO:0042391; GO:0042734; GO:0042995; GO:0044325; GO:0046872; GO:0048167; GO:0048786; GO:0048788; GO:0048791; GO:0050806; GO:0061669; GO:0070062; GO:0097151; GO:1903861; GO:2000463 18385 XM_029356535.2 638 43 71 7 62 Q96CG8 1.51e-43 Collagen triple helix repeat-containing protein 1 Homo sapiens (Human) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005576; GO:0005581; GO:0005615; GO:0016477; GO:0016528; GO:0017147; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0062023; GO:0090090; GO:0090103; GO:0090177 18386 XM_029325903.2 678 285 397 878 575 NA NA NA NA NA NA 18387 XM_044314980.1 10 2 0 0 13 NA NA NA NA NA NA 18388 XM_044329237.1 0 34 0 158 0 NA NA NA NA NA NA 18389 XM_044315714.1 328 174 246 422 231 Q80XJ3 1.82e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 18390 XM_044315714.1 328 174 246 422 231 Q80XJ3 8.18e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 18391 XM_044315714.1 328 174 246 422 231 Q80XJ3 1.19e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 18392 XM_044315714.1 328 174 246 422 231 Q80XJ3 2.15e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 18393 XM_044315714.1 328 174 246 422 231 Q80XJ3 7.04e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 18394 XM_044315714.1 328 174 246 422 231 Q80XJ3 3.24e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 18395 XM_044315714.1 328 174 246 422 231 Q80XJ3 1.47e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 18396 XM_044315714.1 328 174 246 422 231 Q80XJ3 1.59e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 18397 XM_044315714.1 328 174 246 422 231 Q80XJ3 7.05e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 18398 XM_044315714.1 328 174 246 422 231 Q80XJ3 1.33e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 18399 XM_044315714.1 328 174 246 422 231 Q80XJ3 1.5e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 18400 XM_044315714.1 328 174 246 422 231 Q80XJ3 6.2e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 18401 XM_044315714.1 328 174 246 422 231 Q80XJ3 1.62e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 18402 XM_044315714.1 328 174 246 422 231 Q80XJ3 2.93e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 18403 XM_044315714.1 328 174 246 422 231 Q80XJ3 1.44e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 18404 XM_044322494.1 18421 22380 6602 10812 3298 NA NA NA NA NA NA 18405 XR_006397933.1 0 6 0 0 6 NA NA NA NA NA NA 18406 XM_029346588.2 955 676 421 1027 574 Q3TJZ6 2.8e-81 Protein FAM98A Mus musculus (Mouse) lysosome localization [GO:0032418]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of ruffle assembly [GO:1900029]; protein methylation [GO:0006479] GO:0006479; GO:0008276; GO:0008284; GO:0010628; GO:0032418; GO:0072669; GO:1900029 18407 XM_044307349.1 30 3 32 10 147 NA NA NA NA NA NA 18408 XM_029350432.2 117 60 71 93 139 NA NA NA NA NA NA 18409 XM_044327216.1 718 442 825 786 908 P00734 8.72e-56 Prothrombin (EC 3.4.21.5) (Coagulation factor II) [Cleaved into: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain] Homo sapiens (Human) acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, common pathway [GO:0072377]; cell surface receptor signaling pathway [GO:0007166]; cytolysis by host of symbiont cells [GO:0051838]; fibrinolysis [GO:0042730]; ion channel modulating, G protein-coupled receptor signaling pathway [GO:0099105]; ligand-gated ion channel signaling pathway [GO:1990806]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of blood coagulation [GO:0030195]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil-mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of insulin secretion [GO:0032024]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of cytosolic calcium ion concentration [GO:0051480]; response to wounding [GO:0009611]; zymogen activation [GO:0031638] GO:0001530; GO:0001934; GO:0004252; GO:0005096; GO:0005102; GO:0005246; GO:0005509; GO:0005576; GO:0005615; GO:0005788; GO:0005796; GO:0005886; GO:0006508; GO:0006953; GO:0007166; GO:0007596; GO:0008083; GO:0008201; GO:0008284; GO:0008360; GO:0009611; GO:0010544; GO:0014068; GO:0016004; GO:0030168; GO:0030193; GO:0030194; GO:0030195; GO:0030307; GO:0031638; GO:0032024; GO:0032967; GO:0042730; GO:0043539; GO:0045861; GO:0046427; GO:0048712; GO:0051281; GO:0051480; GO:0051838; GO:0051918; GO:0061844; GO:0062023; GO:0070053; GO:0070062; GO:0070945; GO:0072377; GO:0072562; GO:0090218; GO:0099103; GO:0099105; GO:0099107; GO:1900016; GO:1900182; GO:1900738; GO:1905370; GO:1990806; GO:2000379 18410 XM_029335409.2 3444 3314 1660 2950 2157 Q9HAT8 1.43e-148 E3 ubiquitin-protein ligase pellino homolog 2 (Pellino-2) (EC 2.3.2.27) (RING-type E3 ubiquitin transferase pellino homolog 2) Homo sapiens (Human) positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein phosphorylation [GO:0001934]; protein polyubiquitination [GO:0000209]; regulation of Toll signaling pathway [GO:0008592] GO:0000209; GO:0001934; GO:0005829; GO:0008592; GO:0034450; GO:0043123; GO:0043410; GO:0061630 18411 XM_044316159.1 14 0 0 0 0 P47990 4.32e-113 Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase) (XOR)] Gallus gallus (Chicken) urate biosynthetic process [GO:0034418]; xanthine catabolic process [GO:0009115] GO:0004854; GO:0004855; GO:0005506; GO:0005615; GO:0005777; GO:0005829; GO:0009115; GO:0016491; GO:0030151; GO:0034418; GO:0043546; GO:0050660; GO:0051537; GO:0070674; GO:0071949 18412 XM_029339613.2 376 601 261 493 323 NA NA NA NA NA NA 18413 XM_044310085.1 16 12 7 26 25 NA NA NA NA NA NA 18414 XR_006391938.1 14 5 5 14 21 NA NA NA NA NA NA 18415 XM_029343952.2 19 2 17 19 30 NA NA NA NA NA NA 18416 XM_044320053.1 0 0 0 3 53 NA NA NA NA NA NA 18417 XM_029345895.2 0 66 0 0 223 Q059U7 2.34e-158 Protein inturned (Inturned planar cell polarity effector homolog) (PDZ domain-containing protein 6) Mus musculus (Mouse) cell division [GO:0051301]; cilium assembly [GO:0060271]; embryonic digit morphogenesis [GO:0042733]; establishment of planar polarity [GO:0001736]; hair follicle morphogenesis [GO:0031069]; intraciliary transport [GO:0042073]; keratinocyte differentiation [GO:0030216]; limb development [GO:0060173]; motile cilium assembly [GO:0044458]; negative regulation of cell division [GO:0051782]; negative regulation of keratinocyte proliferation [GO:0010839]; nervous system development [GO:0007399]; neural tube development [GO:0021915]; non-motile cilium assembly [GO:1905515]; positive regulation of smoothened signaling pathway [GO:0045880]; protein localization to organelle [GO:0033365]; regulation of cilium assembly [GO:1902017]; regulation of ossification [GO:0030278]; regulation of smoothened signaling pathway [GO:0008589]; roof of mouth development [GO:0060021]; smoothened signaling pathway [GO:0007224]; spinal cord dorsal/ventral patterning [GO:0021513]; tongue morphogenesis [GO:0043587]; vesicle-mediated transport [GO:0016192] GO:0001736; GO:0005737; GO:0005814; GO:0005929; GO:0007224; GO:0007399; GO:0008589; GO:0009986; GO:0010839; GO:0016192; GO:0021513; GO:0021915; GO:0030216; GO:0030278; GO:0031069; GO:0031514; GO:0033365; GO:0035869; GO:0036064; GO:0042073; GO:0042733; GO:0043587; GO:0044458; GO:0045880; GO:0051301; GO:0051782; GO:0060021; GO:0060173; GO:0060271; GO:1902017; GO:1905515 18418 XR_003828355.2 136 121 41 53 171 NA NA NA NA NA NA 18419 XM_029349274.2 196 151 145 196 325 Q6GNL4 4.32e-72 Ciliogenesis and planar polarity effector 2 (REM2- and Rab-like small GTPase 1) Xenopus laevis (African clawed frog) cilium assembly [GO:0060271]; exocytosis [GO:0006887]; neural tube closure [GO:0001843]; protein localization [GO:0008104]; protein transport [GO:0015031]; regulation of exocytosis [GO:0017157]; regulation of vesicle fusion [GO:0031338] GO:0001843; GO:0003924; GO:0005525; GO:0005737; GO:0006887; GO:0008104; GO:0015031; GO:0017157; GO:0031338; GO:0036064; GO:0060271 18420 XM_029330085.2 323 317 306 308 474 Q6AYB3 8.67e-124 Pre-mRNA-splicing factor ISY1 homolog Rattus norvegicus (Rat) generation of catalytic spliceosome for second transesterification step [GO:0000350]; mRNA 3'-splice site recognition [GO:0000389]; mRNA splicing, via spliceosome [GO:0000398] GO:0000350; GO:0000389; GO:0000398; GO:0000974; GO:0005634; GO:0071006; GO:0071013; GO:0071014; GO:0071020 18421 XM_044308620.1 46 6 0 0 0 NA NA NA NA NA NA 18422 XM_044324840.1 0 5 0 1 11 NA NA NA NA NA NA 18423 XM_044324762.1 2298 1292 922 1902 1473 Q96RW7 3.91e-63 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 18424 XM_044324762.1 2298 1292 922 1902 1473 Q96RW7 4.62e-54 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 18425 XM_044324762.1 2298 1292 922 1902 1473 Q96RW7 7.88e-54 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 18426 XM_044324762.1 2298 1292 922 1902 1473 Q96RW7 1.9e-52 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 18427 XM_044324762.1 2298 1292 922 1902 1473 Q96RW7 7.8e-52 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 18428 XM_044324762.1 2298 1292 922 1902 1473 Q96RW7 3.97e-49 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 18429 XM_044324762.1 2298 1292 922 1902 1473 Q96RW7 2.2e-47 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 18430 XM_044324762.1 2298 1292 922 1902 1473 Q96RW7 1.41e-46 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 18431 XM_044324762.1 2298 1292 922 1902 1473 Q96RW7 3.56e-44 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 18432 XM_044324762.1 2298 1292 922 1902 1473 Q96RW7 4.15e-41 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 18433 XM_044324762.1 2298 1292 922 1902 1473 Q96RW7 1.35e-39 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 18434 XM_044324762.1 2298 1292 922 1902 1473 Q96RW7 3.2e-35 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 18435 XM_029348151.2 125 51 38 96 90 E2QSX5 2.07e-53 Intraflagellar transport protein 43 homolog Canis lupus familiaris (Dog) (Canis familiaris) cilium assembly [GO:0060271]; intraciliary retrograde transport [GO:0035721] GO:0005737; GO:0005856; GO:0005929; GO:0030991; GO:0035721; GO:0060271 18436 XR_006394521.1 47 17 7 42 61 NA NA NA NA NA NA 18437 XM_029358594.2 145 162 142 126 74 Q08BG1 9.01e-89 Transmembrane protein with metallophosphoesterase domain (EC 3.1.-.-) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0016020; GO:0016787; GO:0046872 18438 XM_029340156.2 318 123 152 58 48 P97292 3.84e-21 Histamine H2 receptor (H2R) (HH2R) (Gastric receptor I) Mus musculus (Mouse) chemical synaptic transmission [GO:0007268]; digestive tract development [GO:0048565]; epithelial cell morphogenesis [GO:0003382]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; gastric acid secretion [GO:0001696]; gastrin-induced gastric acid secretion [GO:0001698]; gland development [GO:0048732]; histamine-induced gastric acid secretion [GO:0001697]; memory [GO:0007613]; negative regulation of arachidonic acid secretion [GO:1900139]; positive regulation of vasoconstriction [GO:0045907]; regulation of synaptic plasticity [GO:0048167]; toxin transport [GO:1901998]; visual learning [GO:0008542] GO:0001696; GO:0001697; GO:0001698; GO:0003382; GO:0004969; GO:0004993; GO:0005886; GO:0007187; GO:0007268; GO:0007613; GO:0008542; GO:0016020; GO:0030425; GO:0030594; GO:0045202; GO:0045907; GO:0048167; GO:0048565; GO:0048732; GO:1900139; GO:1901363; GO:1901998 18439 XM_044326074.1 36 9 31 7 19 NA NA NA NA NA NA 18440 XM_029342262.2 0 356 0 6 1582 O00712 1.23e-96 Nuclear factor 1 B-type (NF1-B) (Nuclear factor 1/B) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/B) (NF-I/B) (NFI-B) (TGGCA-binding protein) Homo sapiens (Human) anterior commissure morphogenesis [GO:0021960]; brain development [GO:0007420]; cell differentiation involved in salivary gland development [GO:0060689]; chondrocyte differentiation [GO:0002062]; club cell differentiation [GO:0060486]; commissural neuron axon guidance [GO:0071679]; DNA replication [GO:0006260]; glandular epithelial cell differentiation [GO:0002067]; glial cell differentiation [GO:0010001]; hindbrain development [GO:0030902]; lung ciliated cell differentiation [GO:0061141]; negative regulation of DNA binding [GO:0043392]; negative regulation of epithelial cell proliferation involved in lung morphogenesis [GO:2000795]; negative regulation of mesenchymal cell proliferation involved in lung development [GO:2000791]; negative regulation of miRNA transcription [GO:1902894]; negative regulation of stem cell proliferation [GO:2000647]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; principal sensory nucleus of trigeminal nerve development [GO:0021740]; regulation of transcription by RNA polymerase II [GO:0006357]; response to bacterium [GO:0009617]; salivary gland cavitation [GO:0060662]; stem cell proliferation [GO:0072089]; type I pneumocyte differentiation [GO:0060509]; type II pneumocyte differentiation [GO:0060510] GO:0000122; GO:0000785; GO:0000978; GO:0000981; GO:0001228; GO:0001650; GO:0002062; GO:0002067; GO:0003677; GO:0005634; GO:0005654; GO:0006260; GO:0006357; GO:0007420; GO:0009617; GO:0010001; GO:0021740; GO:0021960; GO:0030902; GO:0043392; GO:0044300; GO:0045893; GO:0045944; GO:0060486; GO:0060509; GO:0060510; GO:0060662; GO:0060689; GO:0061141; GO:0071679; GO:0072089; GO:0140416; GO:1902894; GO:1990837; GO:2000647; GO:2000791; GO:2000795 18441 XM_044319513.1 440 373 411 525 803 Q91Z40 8.13e-42 Guanylate-binding protein 7 (EC 3.6.5.-) (GTP-binding protein 7) (GBP-7) (Guanine nucleotide-binding protein 7) (Guanylate-binding protein 4-like) Mus musculus (Mouse) adhesion of symbiont to host [GO:0044406]; cellular response to interferon-beta [GO:0035458]; cellular response to type II interferon [GO:0071346]; defense response to Gram-positive bacterium [GO:0050830]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; negative regulation of cytokine production [GO:0001818]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of type I interferon production [GO:0032480]; negative regulation of type III interferon production [GO:0034345]; positive regulation of viral genome replication [GO:0045070]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122] GO:0001818; GO:0003924; GO:0005525; GO:0016020; GO:0020005; GO:0031410; GO:0032480; GO:0034345; GO:0035458; GO:0042832; GO:0043122; GO:0044406; GO:0045070; GO:0046426; GO:0050830; GO:0051607; GO:0071346 18442 XM_029336661.2 8 52 0 0 23 NA NA NA NA NA NA 18443 XM_044306813.1 1828 429 485 1894 376 Q9W7R4 9.12e-23 Teneurin-3 (Ten-3) (Protein Odd Oz/ten-m homolog 3) (Tenascin-M3) (Ten-m3) (Teneurin transmembrane protein 3) Danio rerio (Zebrafish) (Brachydanio rerio) dendrite guidance [GO:0070983]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron development [GO:0048666]; positive regulation of neuron projection development [GO:0010976]; regulation of homophilic cell adhesion [GO:1903385]; retinal ganglion cell axon guidance [GO:0031290]; signal transduction [GO:0007165]; visual perception [GO:0007601] GO:0005886; GO:0007156; GO:0007157; GO:0007165; GO:0007601; GO:0010976; GO:0016020; GO:0030424; GO:0031290; GO:0042803; GO:0043005; GO:0046982; GO:0048666; GO:0050839; GO:0070983; GO:1903385 18444 XM_029347394.2 9 2 13 12 44 P25931 7.52e-24 RYamide receptor (Neuropeptide Y-like receptor) (NPY-R) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218] GO:0001653; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0016020 18445 XM_029349202.2 21 55 33 20 46 NA NA NA NA NA NA 18446 XR_006392076.1 100 157 446 575 535 NA NA NA NA NA NA 18447 XM_044312799.1 57 90 57 419 0 NA NA NA NA NA NA 18448 XM_044313597.1 96 169 87 399 236 NA NA NA NA NA NA 18449 XM_044307650.1 0 0 144 68 37 Q03146 1.07e-99 Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (Protein-tyrosine kinase MPK-6) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a) Mus musculus (Mouse) axon development [GO:0061564]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell population proliferation [GO:0008283]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; ear development [GO:0043583]; embryo implantation [GO:0007566]; lactation [GO:0007595]; mammary gland alveolus development [GO:0060749]; negative regulation of cell population proliferation [GO:0008285]; neuron projection extension [GO:1990138]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of kinase activity [GO:0033674]; protein autophosphorylation [GO:0046777]; regulation of cell growth [GO:0001558]; regulation of cell-matrix adhesion [GO:0001952]; regulation of extracellular matrix disassembly [GO:0010715]; smooth muscle cell migration [GO:0014909]; smooth muscle cell-matrix adhesion [GO:0061302]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing, spreading of cells [GO:0044319] GO:0001558; GO:0001952; GO:0004714; GO:0005518; GO:0005524; GO:0005737; GO:0005886; GO:0005903; GO:0007169; GO:0007566; GO:0007595; GO:0008283; GO:0008285; GO:0010715; GO:0014909; GO:0016323; GO:0018108; GO:0033674; GO:0038062; GO:0038063; GO:0038083; GO:0043235; GO:0043583; GO:0044319; GO:0046777; GO:0046872; GO:0060444; GO:0060749; GO:0061302; GO:0061564; GO:1990138 18450 XM_044307650.1 0 0 144 68 37 Q03146 1.25e-26 Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (Protein-tyrosine kinase MPK-6) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a) Mus musculus (Mouse) axon development [GO:0061564]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell population proliferation [GO:0008283]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; ear development [GO:0043583]; embryo implantation [GO:0007566]; lactation [GO:0007595]; mammary gland alveolus development [GO:0060749]; negative regulation of cell population proliferation [GO:0008285]; neuron projection extension [GO:1990138]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of kinase activity [GO:0033674]; protein autophosphorylation [GO:0046777]; regulation of cell growth [GO:0001558]; regulation of cell-matrix adhesion [GO:0001952]; regulation of extracellular matrix disassembly [GO:0010715]; smooth muscle cell migration [GO:0014909]; smooth muscle cell-matrix adhesion [GO:0061302]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing, spreading of cells [GO:0044319] GO:0001558; GO:0001952; GO:0004714; GO:0005518; GO:0005524; GO:0005737; GO:0005886; GO:0005903; GO:0007169; GO:0007566; GO:0007595; GO:0008283; GO:0008285; GO:0010715; GO:0014909; GO:0016323; GO:0018108; GO:0033674; GO:0038062; GO:0038063; GO:0038083; GO:0043235; GO:0043583; GO:0044319; GO:0046777; GO:0046872; GO:0060444; GO:0060749; GO:0061302; GO:0061564; GO:1990138 18451 XM_029339686.2 862 511 389 769 648 Q4KM92 4.45e-96 Pseudouridylate synthase 1 homolog (EC 5.4.99.-) (tRNA pseudouridine synthase 1) (EC 5.4.99.12) (tRNA pseudouridine(38-40) synthase) (tRNA pseudouridylate synthase I) (tRNA-uridine isomerase I) Rattus norvegicus (Rat) mRNA processing [GO:0006397]; mRNA pseudouridine synthesis [GO:1990481]; positive regulation of transcription by RNA polymerase II [GO:0045944]; RNA splicing [GO:0008380]; tRNA pseudouridine synthesis [GO:0031119] GO:0000049; GO:0002153; GO:0003682; GO:0005634; GO:0005667; GO:0005730; GO:0005737; GO:0005739; GO:0006397; GO:0008380; GO:0009982; GO:0030374; GO:0031119; GO:0045944; GO:0106029; GO:1990481 18452 XM_029329466.2 838 324 223 301 319 Q13118 1.01e-58 Krueppel-like factor 10 (EGR-alpha) (Transforming growth factor-beta-inducible early growth response protein 1) (TGFB-inducible early growth response protein 1) (TIEG-1) Homo sapiens (Human) bone mineralization [GO:0030282]; cell-cell signaling [GO:0007267]; cellular response to starvation [GO:0009267]; circadian rhythm [GO:0007623]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of circadian rhythm [GO:0042752]; regulation of transcription by RNA polymerase II [GO:0006357]; somatic stem cell population maintenance [GO:0035019] GO:0000122; GO:0000785; GO:0000978; GO:0000981; GO:0001046; GO:0001228; GO:0003700; GO:0005634; GO:0006357; GO:0007267; GO:0007623; GO:0008285; GO:0009267; GO:0030282; GO:0035019; GO:0042752; GO:0045672; GO:0045892; GO:0045944; GO:0046872; GO:1990837 18453 XR_003823487.2 65 9 69 21 133 NA NA NA NA NA NA 18454 XM_029333903.2 153 109 159 96 312 A7SE07 6.37e-137 Cytosolic Fe-S cluster assembly factor NUBP2 homolog Nematostella vectensis (Starlet sea anemone) iron-sulfur cluster assembly [GO:0016226] GO:0005524; GO:0005829; GO:0016226; GO:0046872; GO:0051536; GO:0051539; GO:0140663 18455 XR_006393655.1 0 0 12 0 12 NA NA NA NA NA NA 18456 XM_044317751.1 30 45 5 80 20 P53667 1.83e-109 LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; axon extension [GO:0048675]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; nervous system development [GO:0007399]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of axon extension [GO:0045773]; positive regulation of stress fiber assembly [GO:0051496]; protein phosphorylation [GO:0006468]; Rho protein signal transduction [GO:0007266]; signal transduction [GO:0007165]; stress fiber assembly [GO:0043149] GO:0001673; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0005856; GO:0005925; GO:0006468; GO:0007165; GO:0007266; GO:0007399; GO:0016020; GO:0016607; GO:0030027; GO:0030036; GO:0031072; GO:0032233; GO:0038096; GO:0043005; GO:0043149; GO:0045773; GO:0046872; GO:0048675; GO:0051444; GO:0051496; GO:0106310 18457 XM_044310166.1 0 4 0 2 13 P0CT39 1.66e-78 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 18458 XM_044325399.1 15 36 20 17 61 NA NA NA NA NA NA 18459 XM_029335577.2 573 350 254 396 414 Q7ZV34 1.15e-75 Malignant T-cell-amplified sequence 1 (MCT-1) Danio rerio (Zebrafish) (Brachydanio rerio) cell cycle [GO:0007049]; formation of translation preinitiation complex [GO:0001731] GO:0001731; GO:0003723; GO:0005737; GO:0007049 18460 XM_029343123.2 456 415 211 479 575 Q5R941 4.82e-41 Peptidyl-prolyl cis-trans isomerase FKBP14 (PPIase FKBP14) (EC 5.2.1.8) (FK506-binding protein 14) (FKBP-14) (Rotamase) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003755; GO:0005509; GO:0005788 18461 XM_029342438.2 206 111 57 251 144 Q5SSZ7 2.51e-94 E3 ubiquitin-protein ligase ZNRF3 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase ZNRF3) (Zinc/RING finger protein 3) Mus musculus (Mouse) limb development [GO:0060173]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of Wnt signaling pathway [GO:0030178]; protein ubiquitination [GO:0016567]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; stem cell proliferation [GO:0072089]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt receptor catabolic process [GO:0038018]; Wnt signaling pathway [GO:0016055] GO:0004842; GO:0005109; GO:0005886; GO:0006511; GO:0016055; GO:0016567; GO:0030178; GO:0038018; GO:0046872; GO:0060173; GO:0060828; GO:0061630; GO:0072089; GO:0090090; GO:2000051; GO:2000095 18462 XR_006395379.1 0 0 7 0 0 NA NA NA NA NA NA 18463 XM_029350395.2 1558 931 619 1069 1137 B1AVH7 7.74e-142 TBC1 domain family member 2A Mus musculus (Mouse) activation of GTPase activity [GO:0090630]; positive regulation of GTPase activity [GO:0043547] GO:0005096; GO:0005654; GO:0005829; GO:0005886; GO:0030054; GO:0031410; GO:0043547; GO:0045296; GO:0070161; GO:0090630 18464 XM_044322712.1 4 0 9 0 14 Q9NU22 0 Midasin (Dynein-related AAA-ATPase MDN1) (MIDAS-containing protein) Homo sapiens (Human) ribosomal large subunit assembly [GO:0000027]; ribosomal large subunit export from nucleus [GO:0000055] GO:0000027; GO:0000055; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005829; GO:0016020; GO:0016887; GO:0030687; GO:0045111 18465 XM_044322712.1 4 0 9 0 14 Q9NU22 4.95e-48 Midasin (Dynein-related AAA-ATPase MDN1) (MIDAS-containing protein) Homo sapiens (Human) ribosomal large subunit assembly [GO:0000027]; ribosomal large subunit export from nucleus [GO:0000055] GO:0000027; GO:0000055; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005829; GO:0016020; GO:0016887; GO:0030687; GO:0045111 18466 XM_029332647.2 34 27 9 17 38 NA NA NA NA NA NA 18467 XM_044316794.1 0 2 7 4 41 NA NA NA NA NA NA 18468 XM_044327814.1 41 0 0 42 47 NA NA NA NA NA NA 18469 XR_006396867.1 35 15 4 23 26 NA NA NA NA NA NA 18470 XM_044312268.1 92 3 81 28 121 NA NA NA NA NA NA 18471 XM_029340612.2 104 0 443 2 1093 NA NA NA NA NA NA 18472 XR_006396236.1 3048 2716 1588 2781 4075 NA NA NA NA NA NA 18473 XM_029346328.2 0 1 1 0 11 NA NA NA NA NA NA 18474 XM_044328098.1 50 91 112 73 130 Q8NI77 5.69e-168 Kinesin-like protein KIF18A (Marrow stromal KIF18A) (MS-KIF18A) Homo sapiens (Human) cellular response to estradiol stimulus [GO:0071392]; male meiotic nuclear division [GO:0007140]; microtubule depolymerization [GO:0007019]; microtubule-based movement [GO:0007018]; mitotic metaphase plate congression [GO:0007080]; mitotic sister chromatid segregation [GO:0000070]; protein transport [GO:0015031]; regulation of microtubule cytoskeleton organization [GO:0070507]; seminiferous tubule development [GO:0072520] GO:0000070; GO:0000776; GO:0001726; GO:0003777; GO:0003779; GO:0005524; GO:0005634; GO:0005737; GO:0005815; GO:0005828; GO:0005829; GO:0005871; GO:0005874; GO:0005901; GO:0007018; GO:0007019; GO:0007080; GO:0007140; GO:0008017; GO:0008574; GO:0015031; GO:0015630; GO:0016887; GO:0051010; GO:0061673; GO:0070463; GO:0070507; GO:0071392; GO:0072520; GO:1990023 18475 XM_044308309.1 250 513 664 248 188 P30937 1.52e-21 Somatostatin receptor type 4 (SS-4-R) (SS4-R) (SS4R) Rattus norvegicus (Rat) cell migration [GO:0016477]; cellular response to glucocorticoid stimulus [GO:0071385]; forebrain development [GO:0030900]; negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0106072]; neuropeptide signaling pathway [GO:0007218]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0004930; GO:0004994; GO:0005737; GO:0005886; GO:0007218; GO:0016477; GO:0030900; GO:0042277; GO:0042923; GO:0043005; GO:0070374; GO:0071385; GO:0090238; GO:0106072 18476 XM_029349328.2 171 177 0 190 92 Q9Y6A2 1.26e-86 Cholesterol 24-hydroxylase (CH24H) (EC 1.14.14.25) (Cholesterol 24-monooxygenase) (Cholesterol 24S-hydroxylase) (Cytochrome P450 46A1) Homo sapiens (Human) bile acid biosynthetic process [GO:0006699]; cholesterol catabolic process [GO:0006707]; nervous system development [GO:0007399]; progesterone metabolic process [GO:0042448]; protein localization to membrane raft [GO:1903044]; regulation of long-term synaptic potentiation [GO:1900271]; sterol metabolic process [GO:0016125]; xenobiotic metabolic process [GO:0006805] GO:0005506; GO:0005783; GO:0005789; GO:0006699; GO:0006707; GO:0006805; GO:0007399; GO:0008395; GO:0016125; GO:0020037; GO:0030425; GO:0033781; GO:0042448; GO:0062184; GO:0098793; GO:0098794; GO:1900271; GO:1903044 18477 XM_044306839.1 121 29 42 439 141 NA NA NA NA NA NA 18478 XM_029356247.2 691 453 335 556 710 Q96DP5 1.06e-49 Methionyl-tRNA formyltransferase, mitochondrial (MtFMT) (EC 2.1.2.9) Homo sapiens (Human) conversion of methionyl-tRNA to N-formyl-methionyl-tRNA [GO:0071951] GO:0004479; GO:0005739; GO:0071951 18479 XM_044317500.1 7 0 0 0 0 NA NA NA NA NA NA 18480 XM_029344596.2 6000 12075 9936 2928 4683 P48758 4.19e-119 Carbonyl reductase [NADPH] 1 (EC 1.1.1.184) (15-hydroxyprostaglandin dehydrogenase [NADP(+)]) (EC 1.1.1.196, EC 1.1.1.197) (20-beta-hydroxysteroid dehydrogenase) (Alcohol dehydrogenase [NAD(P)+] CBR1) (EC 1.1.1.71) (NADPH-dependent carbonyl reductase 1) (Prostaglandin 9-ketoreductase) (PG-9-KR) (Prostaglandin-E(2) 9-reductase) (EC 1.1.1.189) Mus musculus (Mouse) glucocorticoid metabolic process [GO:0008211]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; vitamin K metabolic process [GO:0042373]; xenobiotic metabolic process [GO:0006805] GO:0004090; GO:0005634; GO:0005737; GO:0005886; GO:0005902; GO:0006805; GO:0008106; GO:0008211; GO:0016491; GO:0016616; GO:0016655; GO:0035003; GO:0042373; GO:0043231; GO:0047020; GO:0047021; GO:0050221; GO:2000379 18481 XM_029342854.2 224 112 46 206 313 O88351 2.08e-151 Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) (IKK-B) (IKK-beta) (IkBKB) (EC 2.7.11.10) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB) (Serine/threonine protein kinase IKBKB) (EC 2.7.11.1) Mus musculus (Mouse) B cell homeostasis [GO:0001782]; cellular response to tumor necrosis factor [GO:0071356]; cortical actin cytoskeleton organization [GO:0030866]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; I-kappaB phosphorylation [GO:0007252]; interleukin-1-mediated signaling pathway [GO:0070498]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; neuron projection development [GO:0031175]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of sodium ion transport [GO:0010765]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; protein phosphorylation [GO:0006468]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of phosphorylation [GO:0042325]; response to cholecystokinin [GO:0061847]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0001782; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006468; GO:0007249; GO:0007252; GO:0008284; GO:0008384; GO:0008385; GO:0009898; GO:0010765; GO:0010976; GO:0018105; GO:0019901; GO:0019903; GO:0030866; GO:0031175; GO:0033209; GO:0035509; GO:0035631; GO:0042325; GO:0042802; GO:0042803; GO:0043123; GO:0043231; GO:0044877; GO:0045121; GO:0045944; GO:0046982; GO:0051092; GO:0061847; GO:0070498; GO:0071356; GO:0072659; GO:0097110; GO:0106310; GO:1901216; GO:1903140; GO:1903347; GO:1990459; GO:2001259 18482 XM_029350186.2 824 869 431 583 534 P29341 1.17e-24 Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1) Mus musculus (Mouse) CRD-mediated mRNA stabilization [GO:0070934]; mRNA processing [GO:0006397]; negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900152]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cytoplasmic translation [GO:2000767]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; RNA splicing [GO:0008380]; RNA-mediated gene silencing [GO:0031047] GO:0000184; GO:0003723; GO:0003729; GO:0003730; GO:0005634; GO:0005737; GO:0005829; GO:0006397; GO:0008022; GO:0008143; GO:0008266; GO:0008380; GO:0010494; GO:0030027; GO:0030425; GO:0031047; GO:0031252; GO:0036464; GO:0045202; GO:0060213; GO:0070934; GO:0071013; GO:0106002; GO:1900152; GO:1900153; GO:1990124; GO:1990904; GO:2000623; GO:2000767 18483 XM_044308028.1 261 34 59 177 71 B3EWZ3 1.51e-92 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 18484 XM_044308028.1 261 34 59 177 71 B3EWZ3 4.88e-85 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 18485 XM_044308028.1 261 34 59 177 71 B3EWZ3 3.19e-68 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 18486 XM_044308028.1 261 34 59 177 71 B3EWZ3 2.36e-67 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 18487 XM_044308028.1 261 34 59 177 71 B3EWZ3 1.17e-65 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 18488 XM_044308028.1 261 34 59 177 71 B3EWZ3 7.83e-65 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 18489 XM_044308028.1 261 34 59 177 71 B3EWZ3 2.55e-58 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 18490 XM_044308028.1 261 34 59 177 71 B3EWZ3 9.34e-30 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 18491 XM_044319125.1 205 323 0 412 489 NA NA NA NA NA NA 18492 XM_029328237.2 53 0 0 21 0 Q5UNS8 2.18e-26 Uncharacterized protein R665 Acanthamoeba polyphaga mimivirus (APMV) NA NA 18493 XM_029330629.2 39 33 70 61 45 NA NA NA NA NA NA 18494 XM_044322795.1 0 7 6 0 1 NA NA NA NA NA NA 18495 XM_044314510.1 2 303 35 1 455 NA NA NA NA NA NA 18496 XM_029323569.2 0 0 81 284 446 Q5ZII3 2.9e-48 Transmembrane protein adipocyte-associated 1 homolog (Integral membrane protein GPR175) Gallus gallus (Chicken) G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0005886; GO:0007186 18497 XM_044325290.1 0 67 84 43 94 Q6NN55 4.33e-88 Lysophospholipid acyltransferase 6 (LPLAT 6) (EC 2.3.1.-) (EC 2.3.1.23) (EC 2.3.1.n6) (EC 2.3.1.n7) (Membrane-bound acyltransferase 6) (MBOA 6) (Oysgedart) (Oys) Drosophila melanogaster (Fruit fly) germ cell migration [GO:0008354]; lipid modification [GO:0030258]; phospholipid metabolic process [GO:0006644]; plasma membrane organization [GO:0007009]; sperm individualization [GO:0007291] GO:0005783; GO:0006644; GO:0007009; GO:0007291; GO:0008354; GO:0016020; GO:0016746; GO:0030258; GO:0071617 18498 XM_044316103.1 30 95 60 83 195 Q96AY4 8.61e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18499 XM_044316103.1 30 95 60 83 195 Q96AY4 1.16e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18500 XM_044316103.1 30 95 60 83 195 Q96AY4 2.72e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18501 XM_044316103.1 30 95 60 83 195 Q96AY4 1.64e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18502 XM_044316103.1 30 95 60 83 195 Q96AY4 2.15e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18503 XM_029350708.2 1742 2450 1252 3308 2779 A0A096X8J7 0 NA NA NA NA 18504 XM_029338254.2 1298 421 1606 923 1130 O15014 2.74e-22 Zinc finger protein 609 Homo sapiens (Human) muscle organ development [GO:0007517]; positive regulation of neuron migration [GO:2001224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of myoblast proliferation [GO:2000291]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0005634; GO:0005654; GO:0006357; GO:0007517; GO:0045944; GO:0046872; GO:1990841; GO:2000291; GO:2001224 18505 XM_029350400.2 1744 1646 926 2254 1908 Q3B8Q1 3.15e-175 Nucleolar RNA helicase 2 (EC 3.6.4.13) (DEAD box protein 21) (Gu-alpha) (Nucleolar RNA helicase Gu) (Nucleolar RNA helicase II) (RH II/Gu) Rattus norvegicus (Rat) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myeloid dendritic cell cytokine production [GO:0002735]; positive regulation of transcription by RNA polymerase III [GO:0045945]; R-loop processing [GO:0062176]; response to exogenous dsRNA [GO:0043330]; response to virus [GO:0009615]; rRNA processing [GO:0006364]; transcription by RNA polymerase II [GO:0006366] GO:0002735; GO:0003723; GO:0003724; GO:0003725; GO:0005524; GO:0005654; GO:0005730; GO:0005739; GO:0005829; GO:0006364; GO:0006366; GO:0009615; GO:0016887; GO:0019843; GO:0030515; GO:0035198; GO:0042802; GO:0043123; GO:0043330; GO:0045087; GO:0045945; GO:0051607; GO:0062176; GO:0097322; GO:0110016 18506 XM_029331077.2 1225 755 609 1005 1059 Q9U5N1 1.14e-178 V-type proton ATPase subunit C (V-ATPase subunit C) (Vacuolar proton pump subunit C) Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm) NA GO:0033180; GO:0046961 18507 XM_044315928.1 23 3 6 6 7 NA NA NA NA NA NA 18508 XM_029348143.2 3422 3307 1840 2936 3060 P43646 5.8e-46 Caltractin (Centrin) Tetraselmis striata (Green microalga) cell cycle [GO:0007049]; cell division [GO:0051301] GO:0005509; GO:0005815; GO:0007049; GO:0051301 18509 XM_029348245.2 1443 1996 541 96 730 P53111 4.94e-37 NADPH-dependent aldehyde reductase ARI1 (EC 1.1.1.-) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) NA GO:0004090; GO:0005634; GO:0005737; GO:0016491; GO:0016616 18510 XR_006394651.1 3 0 0 8 4 NA NA NA NA NA NA 18511 XM_044317675.1 358 150 177 154 144 Q6GQN5 8.54e-83 Protein phosphatase 1 regulatory subunit 42 (Leucine-rich repeat-containing protein 67) Danio rerio (Zebrafish) (Brachydanio rerio) positive regulation of protein dephosphorylation [GO:0035307] GO:0000164; GO:0002177; GO:0003779; GO:0004865; GO:0005813; GO:0005815; GO:0015630; GO:0015631; GO:0035307; GO:0070840 18512 XM_044325926.1 2892 1843 1731 2677 2767 Q8TDM6 3.9e-108 Disks large homolog 5 (Discs large protein P-dlg) (Placenta and prostate DLG) Homo sapiens (Human) apical protein localization [GO:0045176]; cell-cell adhesion [GO:0098609]; epithelial to mesenchymal transition [GO:0001837]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; intracellular signal transduction [GO:0035556]; maintenance of cell polarity [GO:0030011]; metanephric collecting duct development [GO:0072205]; midbrain development [GO:0030901]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of hippo signaling [GO:0035331]; negative regulation of T cell proliferation [GO:0042130]; neuroepithelial cell differentiation [GO:0060563]; polarized epithelial cell differentiation [GO:0030859]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of hippo signaling [GO:0035332]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of synapse assembly [GO:0051965]; postsynapse organization [GO:0099173]; protein localization to adherens junction [GO:0071896]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; signal transduction [GO:0007165]; zonula adherens assembly [GO:0045186] GO:0001837; GO:0005737; GO:0005886; GO:0005912; GO:0007165; GO:0008013; GO:0008092; GO:0008285; GO:0014069; GO:0030011; GO:0030054; GO:0030159; GO:0030336; GO:0030859; GO:0030901; GO:0035331; GO:0035332; GO:0035556; GO:0036064; GO:0042130; GO:0042981; GO:0045176; GO:0045186; GO:0045197; GO:0045880; GO:0051965; GO:0060441; GO:0060563; GO:0060999; GO:0065003; GO:0071896; GO:0072205; GO:0098609; GO:0098978; GO:0099173 18513 XM_044325926.1 2892 1843 1731 2677 2767 Q8TDM6 3.4e-57 Disks large homolog 5 (Discs large protein P-dlg) (Placenta and prostate DLG) Homo sapiens (Human) apical protein localization [GO:0045176]; cell-cell adhesion [GO:0098609]; epithelial to mesenchymal transition [GO:0001837]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; intracellular signal transduction [GO:0035556]; maintenance of cell polarity [GO:0030011]; metanephric collecting duct development [GO:0072205]; midbrain development [GO:0030901]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of hippo signaling [GO:0035331]; negative regulation of T cell proliferation [GO:0042130]; neuroepithelial cell differentiation [GO:0060563]; polarized epithelial cell differentiation [GO:0030859]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of hippo signaling [GO:0035332]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of synapse assembly [GO:0051965]; postsynapse organization [GO:0099173]; protein localization to adherens junction [GO:0071896]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; signal transduction [GO:0007165]; zonula adherens assembly [GO:0045186] GO:0001837; GO:0005737; GO:0005886; GO:0005912; GO:0007165; GO:0008013; GO:0008092; GO:0008285; GO:0014069; GO:0030011; GO:0030054; GO:0030159; GO:0030336; GO:0030859; GO:0030901; GO:0035331; GO:0035332; GO:0035556; GO:0036064; GO:0042130; GO:0042981; GO:0045176; GO:0045186; GO:0045197; GO:0045880; GO:0051965; GO:0060441; GO:0060563; GO:0060999; GO:0065003; GO:0071896; GO:0072205; GO:0098609; GO:0098978; GO:0099173 18514 XM_029356852.2 19 0 0 23 19 NA NA NA NA NA NA 18515 XM_029355693.2 138 0 0 0 65 Q24322 1.93e-53 Semaphorin-1A (Semaphorin-I) (Sema I) Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; dendrite morphogenesis [GO:0048813]; motor neuron axon guidance [GO:0008045]; negative chemotaxis [GO:0050919]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of cell size [GO:0045792]; positive regulation of cell migration [GO:0030335]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in regulation of photoreceptor cell axon guidance [GO:2000305]; synapse assembly [GO:0007416]; synaptic target recognition [GO:0008039] GO:0005615; GO:0005886; GO:0007411; GO:0007416; GO:0008039; GO:0008045; GO:0008201; GO:0016020; GO:0016199; GO:0030215; GO:0030335; GO:0045499; GO:0045792; GO:0048813; GO:0048843; GO:0050919; GO:0071526; GO:2000305 18516 XR_006394948.1 288 216 238 151 351 NA NA NA NA NA NA 18517 XM_029350399.2 1062 1437 935 1328 1788 Q3B8Q1 1.54e-175 Nucleolar RNA helicase 2 (EC 3.6.4.13) (DEAD box protein 21) (Gu-alpha) (Nucleolar RNA helicase Gu) (Nucleolar RNA helicase II) (RH II/Gu) Rattus norvegicus (Rat) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myeloid dendritic cell cytokine production [GO:0002735]; positive regulation of transcription by RNA polymerase III [GO:0045945]; R-loop processing [GO:0062176]; response to exogenous dsRNA [GO:0043330]; response to virus [GO:0009615]; rRNA processing [GO:0006364]; transcription by RNA polymerase II [GO:0006366] GO:0002735; GO:0003723; GO:0003724; GO:0003725; GO:0005524; GO:0005654; GO:0005730; GO:0005739; GO:0005829; GO:0006364; GO:0006366; GO:0009615; GO:0016887; GO:0019843; GO:0030515; GO:0035198; GO:0042802; GO:0043123; GO:0043330; GO:0045087; GO:0045945; GO:0051607; GO:0062176; GO:0097322; GO:0110016 18518 XM_044314509.1 0 0 9 0 14 NA NA NA NA NA NA 18519 XM_044310314.1 0 5 0 2 7 Q96AY4 1.27e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18520 XM_044315313.1 1130 516 423 233 787 NA NA NA NA NA NA 18521 XR_006396364.1 0 0 0 21 0 NA NA NA NA NA NA 18522 XR_006393486.1 44 56 18 65 49 NA NA NA NA NA NA 18523 XM_044313585.1 0 5 5 7 0 NA NA NA NA NA NA 18524 XM_029326899.2 657 885 340 607 657 Q6DGG0 9.97e-135 Peptidyl-prolyl cis-trans isomerase D (PPIase D) (EC 5.2.1.8) (40 kDa peptidyl-prolyl cis-trans isomerase) (Cyclophilin-40) (CYP-40) (Rotamase D) Rattus norvegicus (Rat) apoptotic process [GO:0006915]; cellular response to UV-A [GO:0071492]; chaperone-mediated protein folding [GO:0061077]; lipid droplet organization [GO:0034389]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein transport [GO:0015031]; protein-containing complex assembly [GO:0065003]; regulation of mitochondrial membrane potential [GO:0051881]; response to oxidative stress [GO:0006979] GO:0000122; GO:0000413; GO:0003755; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005739; GO:0006457; GO:0006915; GO:0006979; GO:0008134; GO:0015031; GO:0016018; GO:0019899; GO:0030331; GO:0030544; GO:0031072; GO:0034389; GO:0043065; GO:0043066; GO:0045070; GO:0050714; GO:0051879; GO:0051881; GO:0061077; GO:0065003; GO:0071492 18525 XM_029341907.2 70 35 25 3 0 P79385 9.51e-24 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (SED1) (Sperm surface protein SP47) (PP47) Sus scrofa (Pig) angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; single fertilization [GO:0007338] GO:0001525; GO:0002080; GO:0005576; GO:0007155; GO:0007338 18526 XM_044313254.1 147 86 40 56 200 P79218 1.6e-31 Substance-K receptor (SKR) (NK-2 receptor) (NK-2R) (Neurokinin A receptor) (Tachykinin receptor 2) Oryctolagus cuniculus (Rabbit) positive regulation of flagellated sperm motility [GO:1902093]; regulation of uterine smooth muscle contraction [GO:0070472] GO:0004995; GO:0005886; GO:0061827; GO:0070472; GO:0097225; GO:1902093 18527 XM_044314834.1 0 167 156 68 0 NA NA NA NA NA NA 18528 XM_029330320.2 7505 4734 4462 5605 5954 Q62829 0 Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (Beta-PAK) (p21-activated kinase 3) (PAK-3) (p65-PAK) Rattus norvegicus (Rat) axonogenesis [GO:0007409]; cellular response to organic cyclic compound [GO:0071407]; dendrite development [GO:0016358]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; intracellular signal transduction [GO:0035556]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of neuron apoptotic process [GO:0043525]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin filament polymerization [GO:0030833]; regulation of axonogenesis [GO:0050770]; regulation of MAPK cascade [GO:0043408]; regulation of neuron projection development [GO:0010975]; regulation of postsynapse organization [GO:0099175] GO:0004672; GO:0004674; GO:0004708; GO:0005524; GO:0005737; GO:0005768; GO:0006468; GO:0007409; GO:0010763; GO:0010975; GO:0014069; GO:0016358; GO:0017124; GO:0030833; GO:0031267; GO:0032956; GO:0035556; GO:0043408; GO:0043525; GO:0046872; GO:0050770; GO:0051020; GO:0060996; GO:0060997; GO:0061003; GO:0071407; GO:0098978; GO:0099175; GO:0106310; GO:2000573 18529 XR_006397528.1 0 0 0 59 120 NA NA NA NA NA NA 18530 XM_029333038.2 159 122 64 142 175 O60235 1.3e-60 Transmembrane protease serine 11D (EC 3.4.21.-) (Airway trypsin-like protease) [Cleaved into: Transmembrane protease serine 11D non-catalytic chain; Transmembrane protease serine 11D catalytic chain] Homo sapiens (Human) proteolysis [GO:0006508]; respiratory gaseous exchange by respiratory system [GO:0007585] GO:0004252; GO:0005576; GO:0005886; GO:0006508; GO:0007585; GO:0008233; GO:0070062 18531 XR_006392887.1 41 2 25 5 151 NA NA NA NA NA NA 18532 XM_044312312.1 21 14 0 11 1 NA NA NA NA NA NA 18533 XR_003826221.2 56 20 39 0 20 NA NA NA NA NA NA 18534 XM_029358741.2 842 829 582 610 500 Q5NCX5 4.1e-24 Neuralized-like protein 4 Mus musculus (Mouse) NA GO:0005737; GO:0005814; GO:0061630 18535 XM_029358741.2 842 829 582 610 500 Q5NCX5 2.87e-22 Neuralized-like protein 4 Mus musculus (Mouse) NA GO:0005737; GO:0005814; GO:0061630 18536 XM_044328019.1 1727 881 505 1088 1144 Q8WVB3 2.01e-99 Hexosaminidase D (EC 3.2.1.52) (Beta-N-acetylhexosaminidase) (Beta-hexosaminidase D) (Hexosaminidase domain-containing protein) (N-acetyl-beta-galactosaminidase) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975] GO:0004563; GO:0005634; GO:0005737; GO:0005975; GO:0015929; GO:0102148; GO:1903561 18537 XM_044310888.1 3 0 6 1 5 NA NA NA NA NA NA 18538 XM_044316921.1 585 1061 231 366 330 P28019 7.85e-55 Dihydrofolate reductase (EC 1.5.1.3) Aedes albopictus (Asian tiger mosquito) (Stegomyia albopicta) glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654] GO:0004146; GO:0006545; GO:0006730; GO:0046654; GO:0050661 18539 XM_029356675.2 1519 1946 731 1725 980 NA NA NA NA NA NA 18540 XR_003825913.2 5 10 4 7 26 NA NA NA NA NA NA 18541 XM_029327370.2 8047 9996 6060 7554 5621 Q7T2B9 4.17e-38 Myotrophin Danio rerio (Zebrafish) (Brachydanio rerio) regulation of barbed-end actin filament capping [GO:2000812] GO:0005634; GO:0005737; GO:0048471; GO:2000812 18542 XM_044322758.1 783 854 0 413 602 NA NA NA NA NA NA 18543 XM_029356456.2 960 407 333 746 871 Q64380 0 Sarcosine dehydrogenase, mitochondrial (SarDH) (EC 1.5.8.3) Rattus norvegicus (Rat) choline catabolic process [GO:0042426]; glycine biosynthetic process [GO:0006545]; sarcosine catabolic process [GO:1901053]; tetrahydrofolate interconversion [GO:0035999] GO:0005542; GO:0005737; GO:0005739; GO:0005759; GO:0006545; GO:0008480; GO:0016491; GO:0035999; GO:0042426; GO:0050660; GO:1901053 18544 XR_006393298.1 13 1 0 0 0 NA NA NA NA NA NA 18545 XM_044311824.1 1029 522 469 488 700 P82251 3.01e-76 b(0,+)-type amino acid transporter 1 (b(0,+)AT1) (Glycoprotein-associated amino acid transporter b0,+AT1) (Solute carrier family 7 member 9) Homo sapiens (Human) L-cystine transport [GO:0015811]; neutral amino acid transport [GO:0015804]; protein-containing complex assembly [GO:0065003] GO:0005886; GO:0015175; GO:0015179; GO:0015184; GO:0015804; GO:0015811; GO:0016324; GO:0031526; GO:0042605; GO:0065003 18546 XM_044309278.1 0 0 0 0 30 NA NA NA NA NA NA 18547 XM_044325198.1 883 710 721 1880 1098 NA NA NA NA NA NA 18548 XM_044320839.1 22 30 0 0 16 NA NA NA NA NA NA 18549 XM_044321400.1 139 79 185 165 142 NA NA NA NA NA NA 18550 XM_029334853.2 1002 633 493 1188 876 Q5BK18 0 Cytosolic iron-sulfur assembly component 3 (Cytosolic Fe-S cluster assembly factor NARFL) (Iron-only hydrogenase-like protein 1) (IOP1) (Nuclear prelamin A recognition factor-like protein) Rattus norvegicus (Rat) cellular oxygen homeostasis [GO:0032364]; hematopoietic progenitor cell differentiation [GO:0002244]; iron-sulfur cluster assembly [GO:0016226]; regulation of gene expression [GO:0010468]; response to hypoxia [GO:0001666] GO:0001666; GO:0002244; GO:0010468; GO:0016226; GO:0032364; GO:0046872; GO:0051539; GO:0097361 18551 XM_044321980.1 89 130 86 285 12 Q7TS68 1.47e-139 tRNA (cytosine(72)-C(5))-methyltransferase NSUN6 (EC 2.1.1.-) (NOL1/NOP2/Sun domain family member 6) Mus musculus (Mouse) RNA methylation [GO:0001510]; tRNA C5-cytosine methylation [GO:0002946]; tRNA methylation [GO:0030488] GO:0000049; GO:0001510; GO:0002946; GO:0005654; GO:0005737; GO:0016428; GO:0030488 18552 XR_006396460.1 8 2 0 2 6 NA NA NA NA NA NA 18553 XM_029352673.2 47 0 50 68 23 P49183 2.08e-66 Deoxyribonuclease-1 (EC 3.1.21.1) (Deoxyribonuclease I) (DNase I) Mus musculus (Mouse) apoptotic process [GO:0006915]; DNA catabolic process [GO:0006308]; DNA catabolic process, endonucleolytic [GO:0000737]; neutrophil activation involved in immune response [GO:0002283]; regulation of acute inflammatory response [GO:0002673]; regulation of neutrophil mediated cytotoxicity [GO:0070948] GO:0000737; GO:0002283; GO:0002673; GO:0003677; GO:0003779; GO:0004530; GO:0004536; GO:0005576; GO:0005634; GO:0005635; GO:0006308; GO:0006915; GO:0042588; GO:0070948 18554 XM_044319984.1 181 18 28 67 22 Q9ULJ7 1.41e-49 Ankyrin repeat domain-containing protein 50 Homo sapiens (Human) endocytic recycling [GO:0032456]; protein transport [GO:0015031] GO:0005768; GO:0015031; GO:0032456 18555 XM_044321175.1 501 893 723 358 967 Q9VBW3 3.61e-59 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 18556 XM_044314233.1 6 15 17 13 42 NA NA NA NA NA NA 18557 XR_006398180.1 6 0 0 1 14 NA NA NA NA NA NA 18558 XM_029338449.2 58 34 44 80 35 O43435 2.38e-100 T-box transcription factor TBX1 (T-box protein 1) (Testis-specific T-box protein) Homo sapiens (Human) angiogenesis [GO:0001525]; anterior/posterior pattern specification [GO:0009952]; aorta morphogenesis [GO:0035909]; artery morphogenesis [GO:0048844]; blood vessel development [GO:0001568]; blood vessel morphogenesis [GO:0048514]; cell fate specification [GO:0001708]; cell population proliferation [GO:0008283]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to retinoic acid [GO:0071300]; cochlea morphogenesis [GO:0090103]; coronary artery morphogenesis [GO:0060982]; determination of left/right symmetry [GO:0007368]; ear morphogenesis [GO:0042471]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic viscerocranium morphogenesis [GO:0048703]; enamel mineralization [GO:0070166]; epithelial cell differentiation [GO:0030855]; face morphogenesis [GO:0060325]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; inner ear morphogenesis [GO:0042472]; lymph vessel development [GO:0001945]; mesenchymal cell apoptotic process [GO:0097152]; mesoderm development [GO:0007498]; middle ear morphogenesis [GO:0042474]; muscle cell fate commitment [GO:0042693]; muscle organ development [GO:0007517]; muscle organ morphogenesis [GO:0048644]; muscle tissue morphogenesis [GO:0060415]; negative regulation of cell differentiation [GO:0045596]; negative regulation of mesenchymal cell apoptotic process [GO:2001054]; neural crest cell migration [GO:0001755]; odontogenesis of dentin-containing tooth [GO:0042475]; outer ear morphogenesis [GO:0042473]; outflow tract morphogenesis [GO:0003151]; outflow tract septum morphogenesis [GO:0003148]; parathyroid gland development [GO:0060017]; pattern specification process [GO:0007389]; pharyngeal system development [GO:0060037]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of tongue muscle cell differentiation [GO:2001037]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of animal organ morphogenesis [GO:2000027]; regulation of transcription by RNA polymerase II [GO:0006357]; retinoic acid receptor signaling pathway [GO:0048384]; semicircular canal morphogenesis [GO:0048752]; sensory perception of sound [GO:0007605]; social behavior [GO:0035176]; soft palate development [GO:0060023]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; tongue morphogenesis [GO:0043587]; vagus nerve morphogenesis [GO:0021644] GO:0000785; GO:0000978; GO:0000981; GO:0001525; GO:0001568; GO:0001708; GO:0001755; GO:0001934; GO:0001945; GO:0002053; GO:0003007; GO:0003148; GO:0003151; GO:0003677; GO:0005634; GO:0006357; GO:0007368; GO:0007389; GO:0007498; GO:0007507; GO:0007517; GO:0007605; GO:0008283; GO:0008284; GO:0009952; GO:0021644; GO:0030855; GO:0030878; GO:0035176; GO:0035909; GO:0042471; GO:0042472; GO:0042473; GO:0042474; GO:0042475; GO:0042693; GO:0042803; GO:0043410; GO:0043565; GO:0043587; GO:0044344; GO:0045596; GO:0045893; GO:0045944; GO:0046983; GO:0048384; GO:0048514; GO:0048538; GO:0048644; GO:0048701; GO:0048703; GO:0048752; GO:0048844; GO:0050679; GO:0060017; GO:0060023; GO:0060037; GO:0060325; GO:0060415; GO:0060982; GO:0070166; GO:0071300; GO:0090103; GO:0097152; GO:1990837; GO:2000027; GO:2001037; GO:2001054 18559 XM_029334565.2 20 0 4 8 13 NA NA NA NA NA NA 18560 XM_044315252.1 3 0 0 0 11 NA NA NA NA NA NA 18561 XM_044319717.1 219 0 0 0 0 NA NA NA NA NA NA 18562 XM_029349402.2 0 0 16 0 70 NA NA NA NA NA NA 18563 XM_044327586.1 425 135 4 10 521 O14672 5.23e-94 Disintegrin and metalloproteinase domain-containing protein 10 (ADAM 10) (EC 3.4.24.81) (CDw156) (Kuzbanian protein homolog) (Mammalian disintegrin-metalloprotease) (CD antigen CD156c) Homo sapiens (Human) adherens junction organization [GO:0034332]; amyloid precursor protein catabolic process [GO:0042987]; cell-cell signaling [GO:0007267]; cochlea development [GO:0090102]; constitutive protein ectodomain proteolysis [GO:0051089]; epidermal growth factor receptor ligand maturation [GO:0038004]; extracellular matrix disassembly [GO:0022617]; in utero embryonic development [GO:0001701]; integrin-mediated signaling pathway [GO:0007229]; membrane protein ectodomain proteolysis [GO:0006509]; monocyte activation [GO:0042117]; negative regulation of cell adhesion [GO:0007162]; negative regulation of gene expression [GO:0010629]; Notch signaling pathway [GO:0007219]; pore complex assembly [GO:0046931]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of T cell chemotaxis [GO:0010820]; postsynapse organization [GO:0099173]; protein catabolic process at postsynapse [GO:0140249]; protein phosphorylation [GO:0006468]; protein processing [GO:0016485]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of Notch signaling pathway [GO:0008593]; regulation of postsynapse organization [GO:0099175]; regulation of vasculature development [GO:1901342]; response to tumor necrosis factor [GO:0034612]; toxin transport [GO:1901998] GO:0000139; GO:0001701; GO:0004175; GO:0004222; GO:0005102; GO:0005178; GO:0005634; GO:0005737; GO:0005788; GO:0005794; GO:0005798; GO:0005886; GO:0005912; GO:0005925; GO:0006468; GO:0006509; GO:0007162; GO:0007219; GO:0007229; GO:0007267; GO:0008237; GO:0008284; GO:0008593; GO:0009986; GO:0010629; GO:0010820; GO:0014069; GO:0016020; GO:0016485; GO:0017124; GO:0019901; GO:0022617; GO:0030136; GO:0030307; GO:0030335; GO:0030424; GO:0030425; GO:0034332; GO:0034612; GO:0035579; GO:0038004; GO:0042117; GO:0042803; GO:0042987; GO:0043231; GO:0046872; GO:0046930; GO:0046931; GO:0051089; GO:0060090; GO:0070062; GO:0070573; GO:0070821; GO:0090102; GO:0097038; GO:0097060; GO:0097197; GO:0098696; GO:0098978; GO:0099173; GO:0099175; GO:0140249; GO:1901342; GO:1901998; GO:1902945 18564 XM_029332358.2 24 21 31 26 16 NA NA NA NA NA NA 18565 XM_029335459.2 288 364 105 180 285 Q9UGM6 1e-109 Tryptophan--tRNA ligase, mitochondrial (EC 6.1.1.2) ((Mt)TrpRS) (Tryptophanyl-tRNA synthetase) (TrpRS) Homo sapiens (Human) mitochondrial tryptophanyl-tRNA aminoacylation [GO:0070183]; positive regulation of angiogenesis [GO:0045766]; tRNA aminoacylation for protein translation [GO:0006418]; tryptophanyl-tRNA aminoacylation [GO:0006436]; vasculogenesis [GO:0001570] GO:0001570; GO:0004830; GO:0005524; GO:0005654; GO:0005739; GO:0005759; GO:0005886; GO:0006418; GO:0006436; GO:0045766; GO:0070183 18566 XM_029332559.2 1356 713 673 1027 945 Q99M87 3.48e-128 DnaJ homolog subfamily A member 3, mitochondrial (DnaJ protein Tid-1) (mTid-1) (Tumorous imaginal discs protein Tid56 homolog) Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation-induced cell death of T cells [GO:0006924]; apoptotic process [GO:0006915]; cellular senescence [GO:0090398]; mitochondrial DNA replication [GO:0006264]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type II interferon-mediated signaling pathway [GO:0060336]; neuromuscular junction development [GO:0007528]; positive regulation of apoptotic process [GO:0043065]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of T cell proliferation [GO:0042102]; protein folding [GO:0006457]; protein stabilization [GO:0050821]; response to heat [GO:0009408]; response to type II interferon [GO:0034341]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; small GTPase mediated signal transduction [GO:0007264]; T cell differentiation in thymus [GO:0033077] GO:0000122; GO:0005133; GO:0005524; GO:0005634; GO:0005737; GO:0005739; GO:0005759; GO:0005829; GO:0005884; GO:0005886; GO:0006264; GO:0006457; GO:0006469; GO:0006915; GO:0006919; GO:0006924; GO:0007005; GO:0007264; GO:0007528; GO:0008285; GO:0009408; GO:0019897; GO:0019901; GO:0030544; GO:0030695; GO:0030971; GO:0031398; GO:0031594; GO:0032088; GO:0033077; GO:0034341; GO:0042102; GO:0042645; GO:0043065; GO:0043066; GO:0043069; GO:0043124; GO:0043154; GO:0043231; GO:0044877; GO:0045211; GO:0046872; GO:0050821; GO:0051059; GO:0051082; GO:0060336; GO:0061629; GO:0071340; GO:0090398; GO:0106137; GO:0140297 18567 XM_029348129.2 84 67 61 88 101 Q66GQ5 2.4e-116 Protein REDUCED WALL ACETYLATION 3 (EC 2.3.1.-) Arabidopsis thaliana (Mouse-ear cress) carbohydrate metabolic process [GO:0005975]; plant-type secondary cell wall biogenesis [GO:0009834]; xylan acetylation [GO:1990937]; xylan biosynthetic process [GO:0045492]; xylan metabolic process [GO:0045491]; xyloglucan metabolic process [GO:0010411] GO:0000139; GO:0005794; GO:0005975; GO:0009834; GO:0010411; GO:0016407; GO:0016491; GO:0045491; GO:0045492; GO:1990937 18568 XM_029342461.2 29 5 7 7 0 Q8SX37 2.89e-27 CDP-diacylglycerol--inositol 3-phosphatidyltransferase (CDIPT) (EC 2.7.8.11) (Phosphatidylinositol synthase) Drosophila melanogaster (Fruit fly) basement membrane organization [GO:0071711]; phosphatidylinositol biosynthetic process [GO:0006661]; phototransduction [GO:0007602] GO:0003881; GO:0005794; GO:0006661; GO:0007602; GO:0016324; GO:0016328; GO:0046872; GO:0071711 18569 XM_044321171.1 44 6 0 3 0 NA NA NA NA NA NA 18570 XM_044323334.1 0 0 85 0 0 Q9H9B1 2.75e-147 Histone-lysine N-methyltransferase EHMT1 (EC 2.1.1.-) (EC 2.1.1.367) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a-like protein 1) (GLP) (GLP1) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Lysine N-methyltransferase 1D) Homo sapiens (Human) chromatin organization [GO:0006325]; DNA methylation [GO:0006306]; facultative heterochromatin formation [GO:0140718]; histone H3-K9 methylation [GO:0051567]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-lysine dimethylation [GO:0018027]; peptidyl-lysine monomethylation [GO:0018026]; positive regulation of cold-induced thermogenesis [GO:0120162]; regulation of embryonic development [GO:0045995]; regulation of histone H3-K9 methylation [GO:0051570] GO:0000122; GO:0000785; GO:0001222; GO:0002039; GO:0005634; GO:0005654; GO:0006306; GO:0006325; GO:0008168; GO:0008270; GO:0016279; GO:0016604; GO:0018024; GO:0018026; GO:0018027; GO:0045892; GO:0045995; GO:0046974; GO:0046976; GO:0051567; GO:0051570; GO:0070742; GO:0120162; GO:0140718; GO:0140947 18571 XM_044322580.1 26 2 157 115 34 P0C0R5 9.43e-32 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) Rattus norvegicus (Rat) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006623; GO:0010506; GO:0015630; GO:0016236; GO:0016241; GO:0030242; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 18572 XM_044322580.1 26 2 157 115 34 P0C0R5 9.43e-32 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) Rattus norvegicus (Rat) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006623; GO:0010506; GO:0015630; GO:0016236; GO:0016241; GO:0030242; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 18573 XM_044322580.1 26 2 157 115 34 P0C0R5 9.43e-32 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) Rattus norvegicus (Rat) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006623; GO:0010506; GO:0015630; GO:0016236; GO:0016241; GO:0030242; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 18574 XM_029357584.2 0 0 0 90 69 Q8BTK5 6.22e-54 SET and MYND domain-containing protein 4 (EC 2.1.1.-) Mus musculus (Mouse) heart development [GO:0007507]; methylation [GO:0032259] GO:0005634; GO:0005737; GO:0007507; GO:0008168; GO:0032259; GO:0042826; GO:0046872 18575 XM_029327536.2 13 0 4 0 0 NA NA NA NA NA NA 18576 XM_044327507.1 232 159 176 263 334 Q3V1V3 1.18e-96 ESF1 homolog (ABT1-associated protein) Mus musculus (Mouse) rRNA processing [GO:0006364] GO:0003723; GO:0005654; GO:0005730; GO:0006364 18577 XM_044318579.1 69 49 36 238 409 Q68F72 2.86e-79 Solute carrier family 15 member 4 Xenopus laevis (African clawed frog) dipeptide import across plasma membrane [GO:0140206]; innate immune response [GO:0045087]; mast cell homeostasis [GO:0033023]; peptidoglycan transport [GO:0015835]; positive regulation of innate immune response [GO:0045089]; positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [GO:0070430]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of toll-like receptor 7 signaling pathway [GO:0034157]; positive regulation of toll-like receptor 8 signaling pathway [GO:0034161]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; protein transport [GO:0015031]; regulation of isotype switching to IgG isotypes [GO:0048302]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424] GO:0005290; GO:0005765; GO:0015031; GO:0015333; GO:0015647; GO:0015835; GO:0031901; GO:0033023; GO:0034157; GO:0034161; GO:0034165; GO:0036020; GO:0045087; GO:0045089; GO:0048302; GO:0070424; GO:0070430; GO:0070434; GO:0071916; GO:0140206 18578 XM_044327959.1 7 2 10 1 8 NA NA NA NA NA NA 18579 XM_044322870.1 161 93 98 121 124 Q9Y4D8 1.19e-40 Probable E3 ubiquitin-protein ligase HECTD4 (EC 2.3.2.26) (HECT domain-containing protein 4) (HECT-type E3 ubiquitin transferase HECTD4) Homo sapiens (Human) glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006] GO:0004842; GO:0006006; GO:0016020; GO:0042593 18580 XM_044321159.1 69 118 48 60 44 NA NA NA NA NA NA 18581 XM_044323678.1 820 597 3 7 955 Q80YS9 2.97e-55 Serine/threonine kinase-like domain-containing protein STKLD1 (Serine/threonine kinase-like domain-containing protein 1) (Sugen kinase 071) Mus musculus (Mouse) protein phosphorylation [GO:0006468] GO:0004674; GO:0005524; GO:0006468 18582 XM_029353292.2 15 2 6 4 51 NA NA NA NA NA NA 18583 XM_044315682.1 42 50 33 42 47 NA NA NA NA NA NA 18584 XM_044319685.1 0 113 64 0 0 NA NA NA NA NA NA 18585 XM_044317788.1 251 0 0 42 0 P55809 0 Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial (SCOT) (EC 2.8.3.5) (3-oxoacid CoA-transferase 1) (Somatic-type succinyl-CoA:3-oxoacid CoA-transferase) (SCOT-s) (Succinyl-CoA:3-oxoacid CoA transferase) Homo sapiens (Human) adipose tissue development [GO:0060612]; brain development [GO:0007420]; cellular ketone body metabolic process [GO:0046950]; heart development [GO:0007507]; ketone body catabolic process [GO:0046952]; ketone catabolic process [GO:0042182]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; response to activity [GO:0014823]; response to ethanol [GO:0045471]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; response to starvation [GO:0042594]; response to xenobiotic stimulus [GO:0009410] GO:0005739; GO:0005759; GO:0007420; GO:0007507; GO:0007584; GO:0008260; GO:0008410; GO:0009410; GO:0009725; GO:0014823; GO:0035774; GO:0042182; GO:0042594; GO:0042802; GO:0045471; GO:0046950; GO:0046952; GO:0060612 18586 XM_044317788.1 251 0 0 42 0 P55809 1.41e-26 Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial (SCOT) (EC 2.8.3.5) (3-oxoacid CoA-transferase 1) (Somatic-type succinyl-CoA:3-oxoacid CoA-transferase) (SCOT-s) (Succinyl-CoA:3-oxoacid CoA transferase) Homo sapiens (Human) adipose tissue development [GO:0060612]; brain development [GO:0007420]; cellular ketone body metabolic process [GO:0046950]; heart development [GO:0007507]; ketone body catabolic process [GO:0046952]; ketone catabolic process [GO:0042182]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; response to activity [GO:0014823]; response to ethanol [GO:0045471]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; response to starvation [GO:0042594]; response to xenobiotic stimulus [GO:0009410] GO:0005739; GO:0005759; GO:0007420; GO:0007507; GO:0007584; GO:0008260; GO:0008410; GO:0009410; GO:0009725; GO:0014823; GO:0035774; GO:0042182; GO:0042594; GO:0042802; GO:0045471; GO:0046950; GO:0046952; GO:0060612 18587 XM_029348086.2 95 38 32 124 49 Q708S4 2.05e-46 Acid-sensing ion channel 4-A (ASIC4-A) (Acid-sensing ion channel 4.1) (Amiloride-sensitive cation channel 4-A) (ZASIC4.1) Danio rerio (Zebrafish) (Brachydanio rerio) sodium ion transmembrane transport [GO:0035725] GO:0005248; GO:0005261; GO:0005886; GO:0015280; GO:0035725; GO:0045177 18588 XM_029334420.2 96 0 17 28 151 Q91981 1.62e-32 Homeobox protein OTX2 (zOTX2) (Orthodenticle homolog 2) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to alcohol [GO:0097306]; cerebellum development [GO:0021549]; hindbrain development [GO:0030902]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; regulation of transcription by RNA polymerase II [GO:0006357]; retinal pigment epithelium development [GO:0003406] GO:0000978; GO:0000981; GO:0003406; GO:0005634; GO:0006357; GO:0021549; GO:0030901; GO:0030902; GO:0030917; GO:0097306 18589 XM_044309183.1 228 159 163 180 175 F1PZV2 2.55e-123 Major facilitator superfamily domain-containing protein 12 Canis lupus familiaris (Dog) (Canis familiaris) carbohydrate transport [GO:0008643]; cysteine transmembrane transport [GO:1903712]; melanin biosynthetic process [GO:0042438]; organic substance transport [GO:0071702]; pigment metabolic process involved in pigmentation [GO:0043474]; regulation of melanin biosynthetic process [GO:0048021] GO:0005764; GO:0005765; GO:0005886; GO:0008643; GO:0015293; GO:0033162; GO:0033229; GO:0042438; GO:0043474; GO:0048021; GO:0071702; GO:1903712 18590 XM_029340719.2 690 1650 684 821 449 Q3UZD5 2.33e-35 Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.361) (PR domain zinc finger protein 6) (PR domain-containing protein 6) (PR domain-containing protein in smooth muscle) Mus musculus (Mouse) chromatin organization [GO:0006325]; histone methylation [GO:0016571]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of smooth muscle cell differentiation [GO:0051151]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of gene expression [GO:0010468] GO:0000122; GO:0005634; GO:0006325; GO:0010468; GO:0016571; GO:0022008; GO:0042802; GO:0045892; GO:0046872; GO:0051151; GO:0140944 18591 XM_029340319.2 930 1021 493 501 625 Q9NS86 3.21e-136 LanC-like protein 2 (Testis-specific adriamycin sensitivity protein) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; negative regulation of DNA-templated transcription [GO:0045892]; peptide modification [GO:0031179]; positive regulation of abscisic acid-activated signaling pathway [GO:0009789] GO:0005524; GO:0005525; GO:0005634; GO:0005654; GO:0005829; GO:0005886; GO:0005975; GO:0009789; GO:0010314; GO:0030864; GO:0031179; GO:0032266; GO:0045892; GO:0070273 18592 XM_044309863.1 36 0 41 14 186 NA NA NA NA NA NA 18593 XM_044316310.1 11 23 20 3 62 NA NA NA NA NA NA 18594 XM_044320370.1 0 22 40 14 1 NA NA NA NA NA NA 18595 XM_029348517.2 0 38 16 62 41 D3YXG0 1.22e-24 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 18596 XM_029348517.2 0 38 16 62 41 D3YXG0 9.82e-22 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 18597 XM_029341763.2 7 0 0 8 0 NA NA NA NA NA NA 18598 XM_029350387.2 276 208 96 98 171 NA NA NA NA NA NA 18599 XM_044319582.1 8 25 5 0 0 Q64287 1.73e-30 Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific interferon regulatory factor) (LSIRF) (NF-EM5) (PU.1 interaction partner) (Transcriptional activator PIP) Mus musculus (Mouse) defense response to protozoan [GO:0042832]; histone H3 acetylation [GO:0043966]; histone H4 acetylation [GO:0043967]; immune system process [GO:0002376]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of DNA binding [GO:0043388]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-13 production [GO:0032736]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; T-helper 17 cell lineage commitment [GO:0072540] GO:0000786; GO:0000978; GO:0000981; GO:0000987; GO:0001228; GO:0002376; GO:0003700; GO:0003713; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0032733; GO:0032736; GO:0032743; GO:0032753; GO:0034122; GO:0042832; GO:0043011; GO:0043388; GO:0043565; GO:0043966; GO:0043967; GO:0045893; GO:0045944; GO:0072540; GO:0120162; GO:1990837 18600 XM_044311286.1 5 6 6 19 13 NA NA NA NA NA NA 18601 XM_029356460.2 4805 2710 2996 2228 1601 Q96CQ1 2.32e-91 Solute carrier family 25 member 36 Homo sapiens (Human) mitochondrial genome maintenance [GO:0000002]; mitochondrion organization [GO:0007005]; pyrimidine nucleotide import into mitochondrion [GO:1990519]; pyrimidine nucleotide transport [GO:0006864]; regulation of mitochondrial membrane potential [GO:0051881] GO:0000002; GO:0005739; GO:0005743; GO:0006864; GO:0007005; GO:0015218; GO:0051881; GO:1990519 18602 XR_006394694.1 2 1 2 10 2 NA NA NA NA NA NA 18603 XM_044321550.1 1 8 0 10 4 NA NA NA NA NA NA 18604 XM_029343300.2 0 24 0 13 0 Q8NCQ5 4.22e-43 F-box only protein 15 Homo sapiens (Human) NA GO:0005829; GO:0019005 18605 XM_044322938.1 586 290 340 460 744 NA NA NA NA NA NA 18606 XR_006396143.1 330 203 127 300 438 D8VNS8 2.86e-62 Ryncolin-2 Cerberus rynchops (Dog-faced water snake) NA GO:0005576; GO:0090729 18607 XR_006396143.1 330 203 127 300 438 D8VNS8 7.32e-61 Ryncolin-2 Cerberus rynchops (Dog-faced water snake) NA GO:0005576; GO:0090729 18608 XR_006393510.1 40 34 51 71 48 NA NA NA NA NA NA 18609 XM_029327715.2 309 573 312 182 408 Q96MB7 3.57e-36 Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease) Homo sapiens (Human) NA GO:0004518; GO:0005634; GO:0005829; GO:0005886; GO:0034451; GO:0046872 18610 XR_006395014.1 11 0 12 9 3 NA NA NA NA NA NA 18611 XR_003824405.2 78 3 0 8 12 NA NA NA NA NA NA 18612 XM_044323026.1 8227 1744 5021 8695 10702 P02466 3.75e-46 Collagen alpha-2(I) chain (Alpha-2 type I collagen) Rattus norvegicus (Rat) blood vessel development [GO:0001568]; bone mineralization [GO:0030282]; cellular response to amino acid stimulus [GO:0071230]; cellular response to organic substance [GO:0071310]; cellular response to retinoic acid [GO:0071300]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; extracellular matrix assembly [GO:0085029]; extracellular matrix organization [GO:0030198]; protein heterotrimerization [GO:0070208]; regulation of blood pressure [GO:0008217]; response to norepinephrine [GO:0071873]; Rho protein signal transduction [GO:0007266]; skeletal system development [GO:0001501]; skin morphogenesis [GO:0043589]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001501; GO:0001568; GO:0002020; GO:0005201; GO:0005576; GO:0005581; GO:0005584; GO:0005615; GO:0007179; GO:0007266; GO:0008217; GO:0030198; GO:0030199; GO:0030282; GO:0030674; GO:0031012; GO:0032963; GO:0042802; GO:0043589; GO:0046332; GO:0046872; GO:0048407; GO:0062023; GO:0070208; GO:0071230; GO:0071300; GO:0071310; GO:0071873; GO:0085029; GO:0097067 18613 XM_029355731.2 59 44 15 6 10 Q9D668 1.5e-35 Arrestin domain-containing protein 2 Mus musculus (Mouse) protein transport [GO:0015031] GO:0005737; GO:0005886; GO:0015031; GO:0031410 18614 XM_044329317.1 0 0 2 0 32 NA NA NA NA NA NA 18615 XR_003828547.2 408 376 194 204 182 NA NA NA NA NA NA 18616 XM_044324162.1 2707 1658 1511 2979 3032 Q9HCK4 1.17e-50 Roundabout homolog 2 Homo sapiens (Human) aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; apoptotic process involved in luteolysis [GO:0061364]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; brain development [GO:0007420]; cell-cell adhesion [GO:0098609]; cellular response to hormone stimulus [GO:0032870]; central nervous system development [GO:0007417]; endocardial cushion formation [GO:0003272]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; metanephros development [GO:0001656]; negative regulation of negative chemotaxis [GO:0050925]; negative regulation of synapse assembly [GO:0051964]; olfactory bulb interneuron development [GO:0021891]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; pulmonary valve morphogenesis [GO:0003184]; retinal ganglion cell axon guidance [GO:0031290]; ureteric bud development [GO:0001657]; ventricular septum morphogenesis [GO:0060412] GO:0001656; GO:0001657; GO:0003148; GO:0003180; GO:0003184; GO:0003272; GO:0005886; GO:0007156; GO:0007411; GO:0007417; GO:0007420; GO:0008046; GO:0009986; GO:0016199; GO:0021891; GO:0030424; GO:0030673; GO:0031290; GO:0032870; GO:0035481; GO:0035904; GO:0042802; GO:0050772; GO:0050925; GO:0051964; GO:0060412; GO:0061364; GO:0070062; GO:0098609; GO:0098632 18617 XM_044324162.1 2707 1658 1511 2979 3032 Q9HCK4 2.34e-50 Roundabout homolog 2 Homo sapiens (Human) aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; apoptotic process involved in luteolysis [GO:0061364]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; brain development [GO:0007420]; cell-cell adhesion [GO:0098609]; cellular response to hormone stimulus [GO:0032870]; central nervous system development [GO:0007417]; endocardial cushion formation [GO:0003272]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; metanephros development [GO:0001656]; negative regulation of negative chemotaxis [GO:0050925]; negative regulation of synapse assembly [GO:0051964]; olfactory bulb interneuron development [GO:0021891]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; pulmonary valve morphogenesis [GO:0003184]; retinal ganglion cell axon guidance [GO:0031290]; ureteric bud development [GO:0001657]; ventricular septum morphogenesis [GO:0060412] GO:0001656; GO:0001657; GO:0003148; GO:0003180; GO:0003184; GO:0003272; GO:0005886; GO:0007156; GO:0007411; GO:0007417; GO:0007420; GO:0008046; GO:0009986; GO:0016199; GO:0021891; GO:0030424; GO:0030673; GO:0031290; GO:0032870; GO:0035481; GO:0035904; GO:0042802; GO:0050772; GO:0050925; GO:0051964; GO:0060412; GO:0061364; GO:0070062; GO:0098609; GO:0098632 18618 XM_029345830.2 14 0 0 33 11 B2GUB3 3.86e-178 Tubulin tyrosine ligase 3 (EC 6.3.2.-) (Tubulin--tyrosine ligase protein 3) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) protein polyglycylation [GO:0018094] GO:0005524; GO:0005737; GO:0005874; GO:0018094; GO:0031514; GO:0046872; GO:0070736 18619 XM_029337377.2 85 17 0 0 0 Q5BJQ5 4.37e-38 GTP-binding protein Rit2 (EC 3.6.5.2) Rattus norvegicus (Rat) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; intracellular signal transduction [GO:0035556]; maintenance of protein location in cell [GO:0032507]; negative regulation of neuron projection development [GO:0010977]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron projection development [GO:0010976]; positive regulation of transcription by RNA polymerase II [GO:0045944]; Ras protein signal transduction [GO:0007265]; regulation of calcium-mediated signaling [GO:0050848]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of endocytosis [GO:0030100]; regulation of protein phosphorylation [GO:0001932] GO:0001932; GO:0003682; GO:0003924; GO:0003925; GO:0005516; GO:0005525; GO:0005634; GO:0005654; GO:0005737; GO:0005794; GO:0005829; GO:0005886; GO:0007189; GO:0007265; GO:0010976; GO:0010977; GO:0019003; GO:0030100; GO:0030215; GO:0032489; GO:0032507; GO:0035556; GO:0043005; GO:0043410; GO:0044297; GO:0045121; GO:0045944; GO:0050848; GO:0097447 18620 XM_029348091.2 60 553 22 99 650 P98064 4.71e-147 Mannan-binding lectin serine protease 1 (EC 3.4.21.-) (Complement factor MASP-3) (Complement-activating component of Ra-reactive factor) (Mannose-binding lectin-associated serine protease 1) (MASP-1) (Mannose-binding protein-associated serine protease) (Ra-reactive factor serine protease p100) (RaRF) (Serine protease 5) [Cleaved into: Mannan-binding lectin serine protease 1 heavy chain; Mannan-binding lectin serine protease 1 light chain] Mus musculus (Mouse) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation, lectin pathway [GO:0001867]; negative regulation of complement activation [GO:0045916]; positive regulation of opsonization [GO:1903028]; proteolysis [GO:0006508] GO:0001867; GO:0002752; GO:0004252; GO:0005509; GO:0005615; GO:0005654; GO:0005829; GO:0006508; GO:0008233; GO:0042802; GO:0042803; GO:0045916; GO:0048306; GO:1903028; GO:1905370 18621 XM_044315846.1 10 0 0 0 1 NA NA NA NA NA NA 18622 XR_006394426.1 2 11 13 3 1 NA NA NA NA NA NA 18623 XM_029349541.2 0 0 42 0 0 Q4U4D2 3.49e-46 Melanopsin (Opsin-4) Podarcis siculus (Italian wall lizard) phototransduction [GO:0007602]; visual perception [GO:0007601] GO:0004930; GO:0005886; GO:0007601; GO:0007602; GO:0009881 18624 XM_029355246.2 577 14 4 11 12 Q9EQC4 9.1e-71 Elongation of very long chain fatty acids protein 4 (EC 2.3.1.199) (3-keto acyl-CoA synthase Elovl4) (ELOVL fatty acid elongase 4) (ELOVL FA elongase 4) (Very long chain 3-ketoacyl-CoA synthase 4) (Very long chain 3-oxoacyl-CoA synthase 4) Mus musculus (Mouse) fatty acid elongation, monounsaturated fatty acid [GO:0034625]; fatty acid elongation, polyunsaturated fatty acid [GO:0034626]; fatty acid elongation, saturated fatty acid [GO:0019367]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; sphingolipid biosynthetic process [GO:0030148]; unsaturated fatty acid biosynthetic process [GO:0006636]; very long-chain fatty acid biosynthetic process [GO:0042761] GO:0005783; GO:0005789; GO:0006636; GO:0009922; GO:0019367; GO:0030148; GO:0034625; GO:0034626; GO:0035338; GO:0042761; GO:0102756 18625 XM_029358628.2 1344 499 403 840 602 Q5FW05 0 Cytoplasmic tRNA 2-thiolation protein 1 (EC 2.7.7.-) (ATP-binding domain-containing protein 3) (Cytoplasmic tRNA adenylyltransferase 1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) protein urmylation [GO:0032447]; tRNA thio-modification [GO:0034227]; tRNA wobble uridine modification [GO:0002098] GO:0000049; GO:0002098; GO:0005829; GO:0016779; GO:0032447; GO:0034227 18626 XM_029325589.2 15 1 987 0 47 NA NA NA NA NA NA 18627 XR_006392572.1 0 0 8 0 0 Q8CJH3 4.07e-58 Plexin-B1 Mus musculus (Mouse) inhibitory synapse assembly [GO:1904862]; negative regulation of cell adhesion [GO:0007162]; negative regulation of osteoblast proliferation [GO:0033689]; neuron projection morphogenesis [GO:0048812]; ossification involved in bone maturation [GO:0043931]; positive regulation of axonogenesis [GO:0050772]; positive regulation of GTPase activity [GO:0043547]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of cytoskeleton organization [GO:0051493]; regulation of GTPase activity [GO:0043087]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis [GO:1900220] GO:0002116; GO:0005886; GO:0007162; GO:0008360; GO:0014068; GO:0017154; GO:0030334; GO:0032794; GO:0033689; GO:0043087; GO:0043547; GO:0043931; GO:0048812; GO:0050772; GO:0051493; GO:0071526; GO:1900220; GO:1902287; GO:1904862 18628 XR_006392572.1 0 0 8 0 0 Q8CJH3 4.07e-58 Plexin-B1 Mus musculus (Mouse) inhibitory synapse assembly [GO:1904862]; negative regulation of cell adhesion [GO:0007162]; negative regulation of osteoblast proliferation [GO:0033689]; neuron projection morphogenesis [GO:0048812]; ossification involved in bone maturation [GO:0043931]; positive regulation of axonogenesis [GO:0050772]; positive regulation of GTPase activity [GO:0043547]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of cytoskeleton organization [GO:0051493]; regulation of GTPase activity [GO:0043087]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis [GO:1900220] GO:0002116; GO:0005886; GO:0007162; GO:0008360; GO:0014068; GO:0017154; GO:0030334; GO:0032794; GO:0033689; GO:0043087; GO:0043547; GO:0043931; GO:0048812; GO:0050772; GO:0051493; GO:0071526; GO:1900220; GO:1902287; GO:1904862 18629 XR_006392572.1 0 0 8 0 0 Q8CJH3 4.07e-58 Plexin-B1 Mus musculus (Mouse) inhibitory synapse assembly [GO:1904862]; negative regulation of cell adhesion [GO:0007162]; negative regulation of osteoblast proliferation [GO:0033689]; neuron projection morphogenesis [GO:0048812]; ossification involved in bone maturation [GO:0043931]; positive regulation of axonogenesis [GO:0050772]; positive regulation of GTPase activity [GO:0043547]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of cytoskeleton organization [GO:0051493]; regulation of GTPase activity [GO:0043087]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis [GO:1900220] GO:0002116; GO:0005886; GO:0007162; GO:0008360; GO:0014068; GO:0017154; GO:0030334; GO:0032794; GO:0033689; GO:0043087; GO:0043547; GO:0043931; GO:0048812; GO:0050772; GO:0051493; GO:0071526; GO:1900220; GO:1902287; GO:1904862 18630 XR_006392572.1 0 0 8 0 0 Q8CJH3 4.07e-58 Plexin-B1 Mus musculus (Mouse) inhibitory synapse assembly [GO:1904862]; negative regulation of cell adhesion [GO:0007162]; negative regulation of osteoblast proliferation [GO:0033689]; neuron projection morphogenesis [GO:0048812]; ossification involved in bone maturation [GO:0043931]; positive regulation of axonogenesis [GO:0050772]; positive regulation of GTPase activity [GO:0043547]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of cytoskeleton organization [GO:0051493]; regulation of GTPase activity [GO:0043087]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis [GO:1900220] GO:0002116; GO:0005886; GO:0007162; GO:0008360; GO:0014068; GO:0017154; GO:0030334; GO:0032794; GO:0033689; GO:0043087; GO:0043547; GO:0043931; GO:0048812; GO:0050772; GO:0051493; GO:0071526; GO:1900220; GO:1902287; GO:1904862 18631 XR_006396929.1 0 11 0 12 3 NA NA NA NA NA NA 18632 XM_029344325.2 1775 1756 1183 1973 2066 O54774 0 AP-3 complex subunit delta-1 (AP-3 complex subunit delta) (Adaptor-related protein complex 3 subunit delta-1) (Delta-adaptin) (mBLVR1) Mus musculus (Mouse) anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; antigen processing and presentation [GO:0019882]; antigen processing and presentation, exogenous lipid antigen via MHC class Ib [GO:0048007]; clathrin-coated vesicle cargo loading, AP-3-mediated [GO:0035654]; endosome to melanosome transport [GO:0035646]; Golgi to vacuole transport [GO:0006896]; intracellular protein transport [GO:0006886]; intracellular transport [GO:0046907]; melanosome assembly [GO:1903232]; neurotransmitter receptor transport, postsynaptic endosome to lysosome [GO:0098943]; platelet dense granule organization [GO:0060155]; positive regulation of NK T cell differentiation [GO:0051138]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to membrane [GO:0072657]; protein localization to organelle [GO:0033365]; protein targeting to vacuole [GO:0006623]; regulation of sequestering of zinc ion [GO:0061088]; synaptic vesicle budding from endosome [GO:0016182]; synaptic vesicle coating [GO:0016183]; synaptic vesicle membrane organization [GO:0048499]; synaptic vesicle recycling [GO:0036465]; vesicle-mediated transport [GO:0016192]; vesicle-mediated transport in synapse [GO:0099003]; zinc ion transport [GO:0006829] GO:0000139; GO:0005769; GO:0005802; GO:0006623; GO:0006829; GO:0006886; GO:0006896; GO:0008089; GO:0010008; GO:0016182; GO:0016183; GO:0016192; GO:0019882; GO:0030123; GO:0030424; GO:0033365; GO:0035646; GO:0035654; GO:0036465; GO:0043195; GO:0045944; GO:0046907; GO:0048007; GO:0048490; GO:0048499; GO:0051138; GO:0060155; GO:0061088; GO:0072657; GO:0098793; GO:0098794; GO:0098830; GO:0098943; GO:0098978; GO:0099003; GO:1903232; GO:1904115 18633 XM_029344325.2 1775 1756 1183 1973 2066 O54774 1.05e-61 AP-3 complex subunit delta-1 (AP-3 complex subunit delta) (Adaptor-related protein complex 3 subunit delta-1) (Delta-adaptin) (mBLVR1) Mus musculus (Mouse) anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; antigen processing and presentation [GO:0019882]; antigen processing and presentation, exogenous lipid antigen via MHC class Ib [GO:0048007]; clathrin-coated vesicle cargo loading, AP-3-mediated [GO:0035654]; endosome to melanosome transport [GO:0035646]; Golgi to vacuole transport [GO:0006896]; intracellular protein transport [GO:0006886]; intracellular transport [GO:0046907]; melanosome assembly [GO:1903232]; neurotransmitter receptor transport, postsynaptic endosome to lysosome [GO:0098943]; platelet dense granule organization [GO:0060155]; positive regulation of NK T cell differentiation [GO:0051138]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to membrane [GO:0072657]; protein localization to organelle [GO:0033365]; protein targeting to vacuole [GO:0006623]; regulation of sequestering of zinc ion [GO:0061088]; synaptic vesicle budding from endosome [GO:0016182]; synaptic vesicle coating [GO:0016183]; synaptic vesicle membrane organization [GO:0048499]; synaptic vesicle recycling [GO:0036465]; vesicle-mediated transport [GO:0016192]; vesicle-mediated transport in synapse [GO:0099003]; zinc ion transport [GO:0006829] GO:0000139; GO:0005769; GO:0005802; GO:0006623; GO:0006829; GO:0006886; GO:0006896; GO:0008089; GO:0010008; GO:0016182; GO:0016183; GO:0016192; GO:0019882; GO:0030123; GO:0030424; GO:0033365; GO:0035646; GO:0035654; GO:0036465; GO:0043195; GO:0045944; GO:0046907; GO:0048007; GO:0048490; GO:0048499; GO:0051138; GO:0060155; GO:0061088; GO:0072657; GO:0098793; GO:0098794; GO:0098830; GO:0098943; GO:0098978; GO:0099003; GO:1903232; GO:1904115 18634 XM_029358370.2 246 263 84 535 325 NA NA NA NA NA NA 18635 XM_044321219.1 5 10 26 12 2 NA NA NA NA NA NA 18636 XM_029350465.2 492 337 124 685 469 Q9H0Z9 2.65e-29 RNA-binding protein 38 (CLL-associated antigen KW-5) (HSRNASEB) (RNA-binding motif protein 38) (RNA-binding region-containing protein 1) (ssDNA-binding protein SEB4) Homo sapiens (Human) 3'-UTR-mediated mRNA stabilization [GO:0070935]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; mRNA processing [GO:0006397]; mRNA stabilization [GO:0048255]; negative regulation of cell population proliferation [GO:0008285]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of cell cycle [GO:0051726]; regulation of myotube differentiation [GO:0010830]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380] GO:0000381; GO:0003723; GO:0003729; GO:0003730; GO:0005634; GO:0005829; GO:0006397; GO:0006977; GO:0006978; GO:0007049; GO:0008285; GO:0008380; GO:0010830; GO:0030154; GO:0043484; GO:0048255; GO:0051726; GO:0070935 18637 XM_029342942.2 2 13 11 9 50 NA NA NA NA NA NA 18638 XM_029350330.2 25 8 468 30 120 NA NA NA NA NA NA 18639 XM_029347657.2 0 0 0 0 15 Q0EEE2 1.85e-68 Patched domain-containing protein 3 (RND-type protein RNDEu-3) Mus musculus (Mouse) NA GO:0005783; GO:0005789; GO:0005886; GO:0016020; GO:0097225 18640 XM_044312220.1 719 580 252 629 908 NA NA NA NA NA NA 18641 XM_044324484.1 10 0 2 13 0 Q9D994 8.83e-58 WD repeat-containing protein 38 Mus musculus (Mouse) hematopoietic progenitor cell differentiation [GO:0002244] GO:0002244 18642 XM_029344806.2 52 41 28 8 13 Q76DT2 1.07e-68 DELTA-thalatoxin-Avl2a (DELTA-TATX-Avl2a) (Toxin AvTX-60A) (Av60A) Actineria villosa (Okinawan sea anemone) hemolysis in another organism [GO:0044179] GO:0005576; GO:0042151; GO:0044179; GO:0090729 18643 XM_029353046.2 53 0 35 44 121 Q9CS74 3.17e-152 Protein ecdysoneless homolog Mus musculus (Mouse) fibroblast proliferation [GO:0048144]; mRNA processing [GO:0006397]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; RNA splicing [GO:0008380] GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006397; GO:0008380; GO:0035035; GO:0045944; GO:0048144; GO:2000045 18644 XM_044314912.1 0 17 0 0 0 NA NA NA NA NA NA 18645 XR_006392480.1 37 30 43 15 54 NA NA NA NA NA NA 18646 XM_029328676.2 31 46 18 12 123 Q640I9 2.37e-109 Lysine-specific demethylase 2B (EC 1.14.11.27) (F-box and leucine-rich repeat protein 10) (F-box/LRR-repeat protein 10) (JmjC domain-containing histone demethylation protein 1B) ([Histone-H3]-lysine-36 demethylase 1B) Xenopus laevis (African clawed frog) chromatin organization [GO:0006325]; histone H3-K36 demethylation [GO:0070544] GO:0005634; GO:0005694; GO:0005730; GO:0006325; GO:0008270; GO:0019843; GO:0045322; GO:0051864; GO:0070544; GO:0140680 18647 XM_029328676.2 31 46 18 12 123 Q640I9 4.61e-61 Lysine-specific demethylase 2B (EC 1.14.11.27) (F-box and leucine-rich repeat protein 10) (F-box/LRR-repeat protein 10) (JmjC domain-containing histone demethylation protein 1B) ([Histone-H3]-lysine-36 demethylase 1B) Xenopus laevis (African clawed frog) chromatin organization [GO:0006325]; histone H3-K36 demethylation [GO:0070544] GO:0005634; GO:0005694; GO:0005730; GO:0006325; GO:0008270; GO:0019843; GO:0045322; GO:0051864; GO:0070544; GO:0140680 18648 XR_006391457.1 101 0 1 106 17 NA NA NA NA NA NA 18649 XM_029337481.2 186 332 56 289 146 P16065 0 Speract receptor (EC 4.6.1.2) (Guanylate cyclase) Strongylocentrotus purpuratus (Purple sea urchin) cGMP biosynthetic process [GO:0006182]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]; receptor guanylyl cyclase signaling pathway [GO:0007168]; signal transduction [GO:0007165] GO:0001653; GO:0004383; GO:0004672; GO:0005524; GO:0005525; GO:0005886; GO:0006182; GO:0006468; GO:0007165; GO:0007168; GO:0035556 18650 XM_044320860.1 636 225 253 505 765 A0JM13 0 C2 domain-containing protein 3 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) centriole elongation [GO:0061511]; non-motile cilium assembly [GO:1905515]; protein localization to centrosome [GO:0071539] GO:0005737; GO:0005814; GO:0005929; GO:0034451; GO:0061511; GO:0071539; GO:1905515 18651 XM_044323361.1 467 221 321 1133 1086 Q8C6K9 1.1e-60 Collagen alpha-6(VI) chain Mus musculus (Mouse) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 18652 XM_044323361.1 467 221 321 1133 1086 Q8C6K9 4.68e-28 Collagen alpha-6(VI) chain Mus musculus (Mouse) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 18653 XM_029341923.2 448 20 538 261 775 P97677 5.77e-84 Delta-like protein 1 (Drosophila Delta homolog 1) (Delta1) Rattus norvegicus (Rat) astrocyte development [GO:0014002]; auditory receptor cell fate commitment [GO:0009912]; cell fate determination [GO:0001709]; cell-cell signaling [GO:0007267]; cerebellar molecular layer formation [GO:0021688]; cerebellar Purkinje cell layer structural organization [GO:0021693]; clathrin-dependent endocytosis [GO:0072583]; compartment pattern specification [GO:0007386]; determination of left/right symmetry [GO:0007368]; endothelial tip cell fate specification [GO:0097102]; energy homeostasis [GO:0097009]; heart looping [GO:0001947]; inhibition of neuroepithelial cell differentiation [GO:0002085]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear development [GO:0048839]; lateral inhibition [GO:0046331]; left/right axis specification [GO:0070986]; loop of Henle development [GO:0072070]; marginal zone B cell differentiation [GO:0002315]; myeloid cell differentiation [GO:0030099]; negative regulation of cardiac muscle cell differentiation [GO:2000726]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal cell differentiation [GO:0045605]; negative regulation of epithelial cell differentiation [GO:0030857]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of inner ear auditory receptor cell differentiation [GO:0045608]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of Notch signaling pathway [GO:0045746]; nephron development [GO:0072006]; nervous system development [GO:0007399]; neuroepithelial cell differentiation [GO:0060563]; neuron differentiation [GO:0030182]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; Notch signaling pathway involved in arterial endothelial cell fate commitment [GO:0060853]; organ growth [GO:0035265]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endocytosis [GO:0045807]; positive regulation of gene expression [GO:0010628]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of skeletal muscle tissue growth [GO:0048633]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proximal tubule development [GO:0072014]; proximal/distal pattern formation [GO:0009954]; regulation of blood pressure [GO:0008217]; regulation of cell adhesion [GO:0030155]; regulation of cell division [GO:0051302]; regulation of growth [GO:0040008]; regulation of neurogenesis [GO:0050767]; regulation of skeletal muscle tissue growth [GO:0048631]; regulation of somitogenesis [GO:0014807]; regulation of vascular endothelial growth factor signaling pathway [GO:1900746]; retina development in camera-type eye [GO:0060041]; retina morphogenesis in camera-type eye [GO:0060042]; skeletal muscle tissue growth [GO:0048630]; skin epidermis development [GO:0098773]; somite specification [GO:0001757]; somitogenesis [GO:0001756]; spinal cord development [GO:0021510]; type B pancreatic cell development [GO:0003323] GO:0001709; GO:0001756; GO:0001757; GO:0001947; GO:0002085; GO:0002315; GO:0003323; GO:0005112; GO:0005509; GO:0005886; GO:0005912; GO:0007219; GO:0007267; GO:0007368; GO:0007386; GO:0007399; GO:0008217; GO:0008284; GO:0008285; GO:0009912; GO:0009954; GO:0010628; GO:0014002; GO:0014807; GO:0016324; GO:0021510; GO:0021688; GO:0021693; GO:0030099; GO:0030155; GO:0030182; GO:0030857; GO:0030957; GO:0031410; GO:0032693; GO:0034351; GO:0035265; GO:0040008; GO:0042491; GO:0045121; GO:0045596; GO:0045605; GO:0045608; GO:0045638; GO:0045662; GO:0045665; GO:0045746; GO:0045747; GO:0045807; GO:0045944; GO:0046331; GO:0048018; GO:0048630; GO:0048631; GO:0048633; GO:0048665; GO:0048839; GO:0050767; GO:0051302; GO:0060041; GO:0060042; GO:0060563; GO:0060853; GO:0070986; GO:0072006; GO:0072014; GO:0072070; GO:0072583; GO:0097009; GO:0097102; GO:0097110; GO:0097150; GO:0098773; GO:1900746; GO:1903672; GO:2000726 18654 XM_044308352.1 101 17 7 198 0 NA NA NA NA NA NA 18655 XM_044326918.1 0 1 23 2 2 NA NA NA NA NA NA 18656 XM_044326739.1 148 0 55 86 0 NA NA NA NA NA NA 18657 XM_029356643.2 32 4 18 0 1 NA NA NA NA NA NA 18658 XM_044308081.1 0 0 0 0 11 Q92113 6.02e-135 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Squalus acanthias (Spiny dogfish) steroid biosynthetic process [GO:0006694] GO:0004508; GO:0005506; GO:0006694; GO:0016020; GO:0020037; GO:0047442 18659 XM_029358250.2 0 0 0 18 0 NA NA NA NA NA NA 18660 XR_006396064.1 44 24 10 0 0 NA NA NA NA NA NA 18661 XM_044319335.1 1159 1305 925 1309 805 Q8VXZ0 1.53e-52 Nudix hydrolase 20, chloroplastic (AtNUDT20) (EC 3.6.1.-) Arabidopsis thaliana (Mouse-ear cress) NA GO:0009507; GO:0044715; GO:0046872 18662 XM_044328026.1 53 61 38 37 13 Q8K2J9 1.16e-76 BTB/POZ domain-containing protein 6 Mus musculus (Mouse) neurogenesis [GO:0022008] GO:0005829; GO:0022008 18663 XM_029331555.2 13359 9854 4432 6961 4511 NA NA NA NA NA NA 18664 XM_029352297.2 58 32 22 41 54 Q9D1I6 1.47e-26 39S ribosomal protein L14, mitochondrial (L14mt) (MRP-L14) Mus musculus (Mouse) mitochondrial translation [GO:0032543] GO:0003735; GO:0005739; GO:0005743; GO:0005762; GO:0032543 18665 XM_044327270.1 207 43 100 46 34 NA NA NA NA NA NA 18666 XM_044323953.1 2492 2341 1083 4018 2876 Q9CPW5 6.3e-56 Translocon-associated protein subunit beta (TRAP-beta) (Signal sequence receptor subunit beta) (SSR-beta) Mus musculus (Mouse) in utero embryonic development [GO:0001701] GO:0001701; GO:0005789 18667 XM_044322627.1 0 4 7 0 21 NA NA NA NA NA NA 18668 XM_029328541.2 3144 3048 1751 2662 2586 Q5R605 1.65e-67 Charged multivesicular body protein 1a (Chromatin-modifying protein 1a) (CHMP1a) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) autophagosome maturation [GO:0097352]; endosome to lysosome transport [GO:0008333]; late endosome to lysosome transport [GO:1902774]; membrane fission [GO:0090148]; midbody abscission [GO:0061952]; mitotic metaphase plate congression [GO:0007080]; negative regulation of cell death [GO:0060548]; nuclear membrane reassembly [GO:0031468]; plasma membrane repair [GO:0001778]; protein transport [GO:0015031]; regulation of mitotic spindle assembly [GO:1901673]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; viral budding from plasma membrane [GO:0046761]; viral budding via host ESCRT complex [GO:0039702] GO:0000776; GO:0001778; GO:0005643; GO:0005765; GO:0005828; GO:0007080; GO:0008333; GO:0015031; GO:0016363; GO:0030496; GO:0031468; GO:0032585; GO:0039702; GO:0043162; GO:0046761; GO:0060548; GO:0061952; GO:0090148; GO:0097352; GO:1901673; GO:1902774; GO:1904930 18669 XM_044322158.1 123 14 122 160 108 NA NA NA NA NA NA 18670 XM_044312016.1 98 1 55 7 86 NA NA NA NA NA NA 18671 XM_029331966.2 0 0 147 0 426 B3EWZ3 8.72e-100 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 18672 XM_029331966.2 0 0 147 0 426 B3EWZ3 1.2e-99 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 18673 XM_029331966.2 0 0 147 0 426 B3EWZ3 2.06e-97 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 18674 XM_029331966.2 0 0 147 0 426 B3EWZ3 2.09e-90 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 18675 XM_029331966.2 0 0 147 0 426 B3EWZ3 1.36e-80 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 18676 XM_029331966.2 0 0 147 0 426 B3EWZ3 2.07e-71 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 18677 XM_029331966.2 0 0 147 0 426 B3EWZ3 1.11e-24 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 18678 XM_029348255.2 206 64 198 155 124 NA NA NA NA NA NA 18679 XM_029324748.2 82 55 38 61 104 NA NA NA NA NA NA 18680 XM_029323980.2 1466 1072 453 1186 1421 NA NA NA NA NA NA 18681 XM_044308320.1 257 142 127 291 163 Q9NUV9 2.95e-22 GTPase IMAP family member 4 (Immunity-associated nucleotide 1 protein) (IAN-1) (hIAN1) (Immunity-associated protein 4) Homo sapiens (Human) NA GO:0005525; GO:0005829; GO:0043231 18682 XM_029344506.2 11 10 0 30 3 P48442 2.59e-44 Extracellular calcium-sensing receptor (CaSR) (Parathyroid cell calcium-sensing receptor) (PCaR1) (RaKCaR) Rattus norvegicus (Rat) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; apoptotic process [GO:0006915]; bile acid secretion [GO:0032782]; branching morphogenesis of an epithelial tube [GO:0048754]; calcium ion import [GO:0070509]; cellular calcium ion homeostasis [GO:0006874]; cellular response to glucose stimulus [GO:0071333]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hypoxia [GO:0071456]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to peptide [GO:1901653]; cellular response to vitamin D [GO:0071305]; chloride transmembrane transport [GO:1902476]; detection of calcium ion [GO:0005513]; fat pad development [GO:0060613]; G protein-coupled receptor signaling pathway [GO:0007186]; JNK cascade [GO:0007254]; ossification [GO:0001503]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of ATP-dependent activity [GO:0032781]; positive regulation of calcium ion import [GO:0090280]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin secretion [GO:0032024]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of vasoconstriction [GO:0045907]; regulation of calcium ion transport [GO:0051924]; response to calcium ion [GO:0051592]; response to fibroblast growth factor [GO:0071774]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to organic cyclic compound [GO:0014070]; vasodilation [GO:0042311] GO:0001503; GO:0002931; GO:0004930; GO:0005178; GO:0005509; GO:0005513; GO:0005634; GO:0005737; GO:0005886; GO:0006874; GO:0006915; GO:0007186; GO:0007193; GO:0007200; GO:0007254; GO:0008284; GO:0009986; GO:0010038; GO:0010628; GO:0014070; GO:0016020; GO:0016323; GO:0016324; GO:0016597; GO:0019901; GO:0030424; GO:0032024; GO:0032781; GO:0032782; GO:0035729; GO:0042311; GO:0042803; GO:0043005; GO:0043025; GO:0043679; GO:0044325; GO:0045907; GO:0048754; GO:0050927; GO:0051592; GO:0051924; GO:0060613; GO:0070374; GO:0070509; GO:0071305; GO:0071333; GO:0071404; GO:0071456; GO:0071774; GO:0090280; GO:1901653; GO:1902476 18683 XM_044327647.1 6 0 2 14 0 NA NA NA NA NA NA 18684 XM_044309145.1 19 7 25 7 0 Q99741 1.16e-132 Cell division control protein 6 homolog (CDC6-related protein) (Cdc18-related protein) (HsCdc18) (p62(cdc6)) (HsCDC6) Homo sapiens (Human) cell division [GO:0051301]; cellular response to angiotensin [GO:1904385]; cellular response to vasopressin [GO:1904117]; DNA replication checkpoint signaling [GO:0000076]; DNA replication initiation [GO:0006270]; mitotic cell cycle [GO:0000278]; mitotic DNA replication checkpoint signaling [GO:0033314]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; positive regulation of chromosome segregation [GO:0051984]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytokinesis [GO:0032467]; positive regulation of fibroblast proliferation [GO:0048146]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; traversing start control point of mitotic cell cycle [GO:0007089] GO:0000076; GO:0000079; GO:0000166; GO:0000278; GO:0000922; GO:0003688; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006270; GO:0007089; GO:0008156; GO:0008285; GO:0019900; GO:0030071; GO:0032467; GO:0033314; GO:0045171; GO:0045737; GO:0048146; GO:0051233; GO:0051301; GO:0051984; GO:0072686; GO:1904117; GO:1904385 18685 XM_044319963.1 0 24 0 64 110 NA NA NA NA NA NA 18686 XR_006396608.1 1 0 41 1 128 NA NA NA NA NA NA 18687 XM_044318107.1 5 45 95 28 119 NA NA NA NA NA NA 18688 XM_029351270.2 1541 959 1063 2600 2749 P55012 0 Solute carrier family 12 member 2 (Basolateral Na-K-Cl symporter) (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2) Mus musculus (Mouse) ammonium transmembrane transport [GO:0072488]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell volume homeostasis [GO:0006884]; cellular chloride ion homeostasis [GO:0030644]; cellular potassium ion homeostasis [GO:0030007]; cellular response to chemokine [GO:1990869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to potassium ion [GO:0035865]; cellular sodium ion homeostasis [GO:0006883]; chloride ion homeostasis [GO:0055064]; chloride transmembrane transport [GO:1902476]; chloride transport [GO:0006821]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; gamma-aminobutyric acid signaling pathway [GO:0007214]; hyperosmotic response [GO:0006972]; inorganic anion import across plasma membrane [GO:0098658]; inorganic cation import across plasma membrane [GO:0098659]; maintenance of blood-brain barrier [GO:0035633]; mammary duct terminal end bud growth [GO:0060763]; multicellular organism growth [GO:0035264]; negative regulation of vascular wound healing [GO:0061044]; positive regulation of aspartate secretion [GO:1904450]; positive regulation of cell volume [GO:0045795]; potassium ion homeostasis [GO:0055075]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transport [GO:0006813]; regulation of matrix metallopeptidase secretion [GO:1904464]; regulation of spontaneous synaptic transmission [GO:0150003]; sodium ion homeostasis [GO:0055078]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814]; T cell chemotaxis [GO:0010818]; transepithelial ammonium transport [GO:0070634]; transepithelial chloride transport [GO:0030321] GO:0005829; GO:0005886; GO:0006813; GO:0006814; GO:0006821; GO:0006883; GO:0006884; GO:0006972; GO:0007214; GO:0008511; GO:0008519; GO:0009925; GO:0010818; GO:0015079; GO:0015377; GO:0015379; GO:0016323; GO:0016324; GO:0016328; GO:0019901; GO:0030007; GO:0030321; GO:0030644; GO:0030659; GO:0035264; GO:0035633; GO:0035725; GO:0035865; GO:0042995; GO:0043005; GO:0043025; GO:0044297; GO:0045795; GO:0046873; GO:0050910; GO:0051087; GO:0051879; GO:0055064; GO:0055075; GO:0055078; GO:0060444; GO:0060763; GO:0061044; GO:0070634; GO:0071222; GO:0071944; GO:0072488; GO:0098658; GO:0098659; GO:0098719; GO:0150003; GO:1902476; GO:1904450; GO:1904464; GO:1990573; GO:1990869 18689 XM_029337069.2 45 0 0 67 33 NA NA NA NA NA NA 18690 XM_029356269.2 217 192 120 210 314 P22045 8.73e-44 9,11-endoperoxide prostaglandin H2 reductase (EC 1.1.1.-) (Prostaglandin F2-alpha synthase) Leishmania major prostaglandin biosynthetic process [GO:0001516] GO:0000166; GO:0001516; GO:0005737; GO:0036130 18691 XR_006392430.1 15 0 16 28 23 NA NA NA NA NA NA 18692 XR_006396768.1 38 3 24 3 72 NA NA NA NA NA NA 18693 XM_044309547.1 0 0 1 1 29 NA NA NA NA NA NA 18694 XM_029339684.2 2484 1476 1503 2098 1971 NA NA NA NA NA NA 18695 XM_044326510.1 114 62 100 199 208 B8VIU6 8.29e-78 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 18696 XR_006392603.1 22 31 84 33 132 NA NA NA NA NA NA 18697 XM_044318124.1 98250 59018 21954 51533 25050 NA NA NA NA NA NA 18698 XM_029355553.2 48 2 0 144 114 NA NA NA NA NA NA 18699 XM_029356422.2 67 21 11 0 0 NA NA NA NA NA NA 18700 XM_029323730.2 674 373 406 546 757 Q7Z3F1 3.77e-89 Integral membrane protein GPR155 (G-protein coupled receptor PGR22) Homo sapiens (Human) cognition [GO:0050890]; intracellular signal transduction [GO:0035556]; transmembrane transport [GO:0055085] GO:0016020; GO:0035556; GO:0050890; GO:0055085; GO:0070062 18701 XM_029323730.2 674 373 406 546 757 Q7Z3F1 4.37e-23 Integral membrane protein GPR155 (G-protein coupled receptor PGR22) Homo sapiens (Human) cognition [GO:0050890]; intracellular signal transduction [GO:0035556]; transmembrane transport [GO:0055085] GO:0016020; GO:0035556; GO:0050890; GO:0055085; GO:0070062 18702 XM_029331056.2 154 102 0 62 0 Q7SY75 1.05e-62 Neurocalcin-delta Xenopus laevis (African clawed frog) NA GO:0005509 18703 XM_029324855.2 17 23 0 24 15 P10394 3.11e-68 Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 18704 XM_029340351.2 53 131 63 66 62 Q27312 1.4e-45 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase (EC 3.2.2.6) (2'-phospho-ADP-ribosyl cyclase) (2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase) (EC 2.4.99.20) (2'-phospho-cyclic-ADP-ribose transferase) (ADP-ribosyl cyclase) (ADPRC) (ADRC) (NAD glycohydrolase) (NAD(+) nucleosidase) (NADase) Aplysia kurodai (Kuroda's sea hare) single fertilization [GO:0007338] GO:0007338; GO:0016020; GO:0016740; GO:0031410; GO:0050135; GO:0061809 18705 XR_003828281.2 4 0 0 1 10 NA NA NA NA NA NA 18706 XM_029336465.2 93 31 30 63 87 Q866A2 2.19e-88 Neuronal acetylcholine receptor subunit alpha-7 Macaca mulatta (Rhesus macaque) associative learning [GO:0008306]; B cell activation [GO:0042113]; behavioral response to ethanol [GO:0048149]; behavioral response to nicotine [GO:0035095]; calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; cognition [GO:0050890]; dendrite arborization [GO:0140059]; dendritic spine organization [GO:0097061]; endocytosis [GO:0006897]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; generation of ovulation cycle rhythm [GO:0060112]; ion transmembrane transport [GO:0034220]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of tumor necrosis factor production [GO:0032720]; nervous system process [GO:0050877]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of CoA-transferase activity [GO:1905920]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure [GO:0001988]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; regulation of amyloid fibril formation [GO:1905906]; regulation of membrane potential [GO:0042391]; regulation of neuron death [GO:1901214]; regulation of norepinephrine secretion [GO:0014061]; regulation of synaptic transmission, dopaminergic [GO:0032225]; response to amyloid-beta [GO:1904645]; response to cold [GO:0009409]; response to food [GO:0032094]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; sensory processing [GO:0050893]; short-term memory [GO:0007614]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271]; T cell activation [GO:0042110] GO:0001540; GO:0001666; GO:0001933; GO:0001988; GO:0005231; GO:0005886; GO:0005892; GO:0006816; GO:0006874; GO:0006897; GO:0007165; GO:0007268; GO:0007271; GO:0007614; GO:0008284; GO:0008306; GO:0009409; GO:0009897; GO:0014061; GO:0015464; GO:0015643; GO:0016324; GO:0017081; GO:0022848; GO:0030317; GO:0030594; GO:0030673; GO:0032094; GO:0032225; GO:0032691; GO:0032715; GO:0032720; GO:0033138; GO:0034220; GO:0035094; GO:0035095; GO:0042110; GO:0042113; GO:0042166; GO:0042391; GO:0042734; GO:0042803; GO:0043005; GO:0043410; GO:0045202; GO:0045766; GO:0048149; GO:0050728; GO:0050877; GO:0050890; GO:0050893; GO:0051649; GO:0060112; GO:0070374; GO:0097061; GO:0098839; GO:0098978; GO:0098981; GO:0140059; GO:1900273; GO:1901214; GO:1902004; GO:1904315; GO:1904645; GO:1905906; GO:1905920; GO:2000463 18707 XM_044320037.1 48 11 227 23 114 Q8BXN7 1.2e-77 Protein phosphatase 1K, mitochondrial (EC 3.1.3.16) (Protein phosphatase 2C isoform kappa) (PP2C-kappa) Mus musculus (Mouse) peptidyl-threonine dephosphorylation [GO:0035970] GO:0004722; GO:0005739; GO:0005759; GO:0017018; GO:0035970; GO:0046872 18708 XR_003826741.2 12 0 0 0 0 NA NA NA NA NA NA 18709 XM_029346729.2 5 6 0 10 9 NA NA NA NA NA NA 18710 XM_029349641.2 197 217 172 2 11 O57321 2.23e-133 Excitatory amino acid transporter 1 (SEAAT1) (Sodium-dependent glutamate/aspartate transporter) (GLAST) Ambystoma tigrinum (Eastern tiger salamander) chloride transmembrane transport [GO:1902476]; D-aspartate import across plasma membrane [GO:0070779]; L-aspartate import across plasma membrane [GO:0140009]; L-glutamate import across plasma membrane [GO:0098712]; potassium ion transmembrane transport [GO:0071805] GO:0005314; GO:0005886; GO:0015501; GO:0046872; GO:0070779; GO:0071805; GO:0098712; GO:0140009; GO:1902476 18711 XR_006393021.1 32 0 1 0 0 NA NA NA NA NA NA 18712 XM_029351798.2 1798 3597 888 1248 1067 P54106 2.36e-38 Methylosome subunit pICln (Chloride conductance regulatory protein ICln) (I(Cln)) Xenopus laevis (African clawed frog) cell volume homeostasis [GO:0006884]; chloride transport [GO:0006821]; spliceosomal snRNP assembly [GO:0000387] GO:0000387; GO:0005634; GO:0005829; GO:0005856; GO:0005886; GO:0006821; GO:0006884; GO:0034709; GO:0034715 18713 XM_029352705.2 255 227 154 173 357 Q6AXX1 6.38e-24 Schlafen-like protein 1 Rattus norvegicus (Rat) NA GO:0005524 18714 XR_006395676.1 124 6 83 178 130 NA NA NA NA NA NA 18715 XM_044315245.1 53 12 60 27 66 NA NA NA NA NA NA 18716 XM_044320016.1 576 805 391 465 484 Q9V6Y3 4.12e-29 Probable 28S ribosomal protein S16, mitochondrial (MRP-S16) (S16mt) Drosophila melanogaster (Fruit fly) mitochondrial translation [GO:0032543] GO:0003735; GO:0005763; GO:0015935; GO:0032543 18717 XM_029332412.2 1092 1660 1130 696 1113 P54357 3.32e-35 Myosin-2 essential light chain (Myosin II essential light chain) (Non-muscle myosin essential light chain) Drosophila melanogaster (Fruit fly) actin filament-based movement [GO:0030048] GO:0005509; GO:0005829; GO:0016460; GO:0017022; GO:0030048; GO:0031475; GO:0031476; GO:0031477; GO:0032036 18718 XM_029336532.2 0 15 2 7 0 P12256 9.01e-41 Penicillin acylase (EC 3.5.1.11) (Penicillin V amidase) (PVA) Lysinibacillus sphaericus (Bacillus sphaericus) response to antibiotic [GO:0046677] GO:0008953; GO:0046677 18719 XM_029337578.2 1535 1802 1230 1437 1370 B6ZLK2 0 Chromodomain-helicase-DNA-binding protein 1 (CHD-1) (EC 3.6.4.12) (ATP-dependent helicase CHD1) Gallus gallus (Chicken) chromatin remodeling [GO:0006338]; nucleosome organization [GO:0034728]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000775; GO:0000785; GO:0003677; GO:0003682; GO:0004386; GO:0005524; GO:0005634; GO:0006338; GO:0006357; GO:0016887; GO:0034728; GO:0042393; GO:0140658 18720 XM_029337578.2 1535 1802 1230 1437 1370 B6ZLK2 1.46e-27 Chromodomain-helicase-DNA-binding protein 1 (CHD-1) (EC 3.6.4.12) (ATP-dependent helicase CHD1) Gallus gallus (Chicken) chromatin remodeling [GO:0006338]; nucleosome organization [GO:0034728]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000775; GO:0000785; GO:0003677; GO:0003682; GO:0004386; GO:0005524; GO:0005634; GO:0006338; GO:0006357; GO:0016887; GO:0034728; GO:0042393; GO:0140658 18721 XM_029334487.2 100 149 512 751 293 Q9CXL1 8.47e-37 Transmembrane protein 50A (Small membrane protein 1) Mus musculus (Mouse) late endosome to vacuole transport via multivesicular body sorting pathway [GO:0032511] GO:0005737; GO:0005783; GO:0016020; GO:0032511; GO:0043025; GO:0097386 18722 XR_006391494.1 108 76 1 90 46 NA NA NA NA NA NA 18723 XR_006392437.1 9 53 4 4 154 NA NA NA NA NA NA 18724 XM_044325912.1 0 261 198 150 0 NA NA NA NA NA NA 18725 XM_029335554.2 219 638 292 181 310 NA NA NA NA NA NA 18726 XM_029351566.2 72 6 0 8 0 Q5EAR5 3.77e-68 tRNA 2'-phosphotransferase 1 (EC 2.7.1.160) Danio rerio (Zebrafish) (Brachydanio rerio) tRNA processing [GO:0008033]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388] GO:0000215; GO:0006388; GO:0008033 18727 XM_044308460.1 19 71 18 22 18 NA NA NA NA NA NA 18728 XM_044322565.1 35 0 0 21 0 NA NA NA NA NA NA 18729 XM_029352423.2 1541 1519 625 3006 2351 NA NA NA NA NA NA 18730 XM_044315907.1 49 50 28 44 44 NA NA NA NA NA NA 18731 XM_029334481.2 130 5 18 188 113 Q3U9N9 4.78e-51 Monocarboxylate transporter 10 (MCT 10) (Aromatic amino acid transporter 1) (Solute carrier family 16 member 10) (T-type amino acid transporter 1) Mus musculus (Mouse) aromatic amino acid transport [GO:0015801]; thyroid hormone generation [GO:0006590]; thyroid hormone transport [GO:0070327]; thyroid-stimulating hormone secretion [GO:0070460] GO:0005302; GO:0005886; GO:0006590; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0030054; GO:0043231; GO:0070327; GO:0070460 18732 XM_044324227.1 34 15 110 26 199 NA NA NA NA NA NA 18733 XM_029340472.2 40 32 69 146 63 Q15811 3.85e-23 Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17) Homo sapiens (Human) clathrin-dependent synaptic vesicle endocytosis [GO:0150007]; endocytosis [GO:0006897]; endosomal transport [GO:0016197]; exocytosis [GO:0006887]; intracellular signal transduction [GO:0035556]; protein localization [GO:0008104]; protein transport [GO:0015031]; regulation of small GTPase mediated signal transduction [GO:0051056] GO:0005085; GO:0005509; GO:0005635; GO:0005737; GO:0005829; GO:0005886; GO:0005905; GO:0006887; GO:0006897; GO:0008104; GO:0015031; GO:0016197; GO:0030027; GO:0035556; GO:0043005; GO:0051056; GO:0055037; GO:0060090; GO:0070064; GO:0098793; GO:0150007 18734 XM_044327300.1 28 95 70 99 4 NA NA NA NA NA NA 18735 XM_044307702.1 1980 2056 720 1416 594 NA NA NA NA NA NA 18736 XM_029328743.2 129 195 66 125 254 O18835 0 Beta-glucuronidase (EC 3.2.1.31) Canis lupus familiaris (Dog) (Canis familiaris) carbohydrate metabolic process [GO:0005975] GO:0004566; GO:0005764; GO:0005975 18737 XM_044329219.1 70 24 84 48 44 NA NA NA NA NA NA 18738 XM_029333812.2 18725 17139 14793 18463 15937 Q5BL41 0 Actin-related protein 2 (Actin-like protein 2) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) Arp2/3 complex-mediated actin nucleation [GO:0034314]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0003779; GO:0005524; GO:0005634; GO:0005737; GO:0005885; GO:0034314; GO:0035861; GO:0042995; GO:0045944; GO:1905168 18739 XM_044308781.1 148 65 37 41 46 P15388 1.39e-99 Potassium voltage-gated channel subfamily C member 1 (NGK2) (Voltage-gated potassium channel subunit Kv3.1) (Voltage-gated potassium channel subunit Kv4) Mus musculus (Mouse) cellular response to xenobiotic stimulus [GO:0071466]; cerebellum development [GO:0021549]; corpus callosum development [GO:0022038]; globus pallidus development [GO:0021759]; optic nerve development [GO:0021554]; positive regulation of ion transmembrane transport [GO:0034767]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of voltage-gated potassium channel activity [GO:1903818]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; protein tetramerization [GO:0051262]; regulation of ion transmembrane transport [GO:0034765]; regulation of potassium ion transmembrane transport [GO:1901379]; response to amine [GO:0014075]; response to auditory stimulus [GO:0010996]; response to fibroblast growth factor [GO:0071774]; response to light intensity [GO:0009642]; response to nerve growth factor [GO:1990089]; response to potassium ion [GO:0035864]; response to toxic substance [GO:0009636] GO:0005249; GO:0005251; GO:0008076; GO:0009636; GO:0009642; GO:0009986; GO:0010996; GO:0014075; GO:0016020; GO:0019894; GO:0021549; GO:0021554; GO:0021759; GO:0022038; GO:0030424; GO:0030425; GO:0030673; GO:0032589; GO:0032590; GO:0032809; GO:0034765; GO:0034767; GO:0035864; GO:0042734; GO:0043025; GO:0044305; GO:0044325; GO:0045211; GO:0051260; GO:0051262; GO:0071466; GO:0071774; GO:0071805; GO:0099508; GO:1901379; GO:1901381; GO:1903818; GO:1990089 18740 XM_029339208.2 21238 11915 11644 26079 22197 P00920 6.39e-50 Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase II) (CA-II) Mus musculus (Mouse) angiotensin-activated signaling pathway [GO:0038166]; carbon dioxide transport [GO:0015670]; morphogenesis of an epithelium [GO:0002009]; neuron cellular homeostasis [GO:0070050]; one-carbon metabolic process [GO:0006730]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; regulation of pH [GO:0006885]; secretion [GO:0046903] GO:0002009; GO:0004064; GO:0004089; GO:0005615; GO:0005737; GO:0005829; GO:0005886; GO:0005902; GO:0006730; GO:0006885; GO:0008270; GO:0015670; GO:0016323; GO:0016836; GO:0030424; GO:0032230; GO:0032849; GO:0038166; GO:0043209; GO:0044070; GO:0045177; GO:0045672; GO:0045780; GO:0046903; GO:0051453; GO:0070050; GO:2001150; GO:2001225 18741 XM_029339208.2 21238 11915 11644 26079 22197 P00920 5.03e-47 Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase II) (CA-II) Mus musculus (Mouse) angiotensin-activated signaling pathway [GO:0038166]; carbon dioxide transport [GO:0015670]; morphogenesis of an epithelium [GO:0002009]; neuron cellular homeostasis [GO:0070050]; one-carbon metabolic process [GO:0006730]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; regulation of pH [GO:0006885]; secretion [GO:0046903] GO:0002009; GO:0004064; GO:0004089; GO:0005615; GO:0005737; GO:0005829; GO:0005886; GO:0005902; GO:0006730; GO:0006885; GO:0008270; GO:0015670; GO:0016323; GO:0016836; GO:0030424; GO:0032230; GO:0032849; GO:0038166; GO:0043209; GO:0044070; GO:0045177; GO:0045672; GO:0045780; GO:0046903; GO:0051453; GO:0070050; GO:2001150; GO:2001225 18742 XM_044322553.1 0 11 0 0 12 NA NA NA NA NA NA 18743 XR_006393127.1 7 2 5 0 0 NA NA NA NA NA NA 18744 XM_029357036.2 528 520 201 507 223 Q502W6 2.65e-22 von Willebrand factor A domain-containing protein 3B (VWA domain-containing protein 3B) Homo sapiens (Human) NA GO:0005654; GO:0005829 18745 XM_029333341.2 3642 2741 1283 2845 2244 Q498D6 7.36e-113 Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen CD334) Rattus norvegicus (Rat) alveolar secondary septum development [GO:0061144]; cell migration [GO:0016477]; cholesterol homeostasis [GO:0042632]; fibroblast growth factor receptor signaling pathway [GO:0008543]; glucose homeostasis [GO:0042593]; lung development [GO:0030324]; negative regulation of fibroblast growth factor production [GO:0090272]; negative regulation of gene expression [GO:0010629]; organ induction [GO:0001759]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphate ion homeostasis [GO:0055062]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of parathyroid hormone secretion [GO:2000830]; positive regulation of proteolysis [GO:0045862]; protein autophosphorylation [GO:0046777]; regulation of bile acid biosynthetic process [GO:0070857]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of lipid metabolic process [GO:0019216]; regulation of phosphate transport [GO:0010966]; regulation of phosphorus metabolic process [GO:0051174]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vitamin D3 metabolic process [GO:0070640] GO:0001759; GO:0004714; GO:0005007; GO:0005524; GO:0005768; GO:0005783; GO:0005794; GO:0005886; GO:0005911; GO:0007169; GO:0008201; GO:0008284; GO:0008543; GO:0010628; GO:0010629; GO:0010715; GO:0010966; GO:0016477; GO:0017134; GO:0018108; GO:0019216; GO:0030133; GO:0030324; GO:0033674; GO:0042593; GO:0042632; GO:0043085; GO:0043235; GO:0045862; GO:0046777; GO:0051174; GO:0055062; GO:0061144; GO:0070374; GO:0070640; GO:0070857; GO:0090272; GO:2000573; GO:2000830 18746 XM_044327589.1 281 164 22 50 1 NA NA NA NA NA NA 18747 XM_044322023.1 663 294 237 336 0 C5H5C4 2.56e-80 Palmitoleoyl-protein carboxylesterase notum1a (EC 3.1.1.98) Danio rerio (Zebrafish) (Brachydanio rerio) anterior/posterior pattern specification [GO:0009952]; GPI anchor release [GO:0006507]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of Wnt signaling pathway [GO:0030178]; neural tube patterning [GO:0021532]; protein depalmitoleylation [GO:1990697]; Wnt signaling pathway [GO:0016055] GO:0005576; GO:0006507; GO:0009952; GO:0016055; GO:0021532; GO:0030178; GO:0090090; GO:1990697; GO:1990699 18748 XM_029327461.2 2450 1510 754 1238 3528 O61231 2.51e-129 60S ribosomal protein L10 (QM protein homolog) (dQM) Drosophila melanogaster (Fruit fly) cytoplasmic translation [GO:0002181]; ribosomal large subunit assembly [GO:0000027] GO:0000027; GO:0002181; GO:0003735; GO:0005737; GO:0022625; GO:0022626; GO:0043025 18749 XM_029338001.2 62 68 129 71 179 NA NA NA NA NA NA 18750 XM_029329009.2 1169 1151 635 761 734 Q9Y4Z0 2.09e-53 U6 snRNA-associated Sm-like protein LSm4 (Glycine-rich protein) (GRP) Homo sapiens (Human) mRNA splicing, via spliceosome [GO:0000398]; nuclear-transcribed mRNA catabolic process [GO:0000956]; P-body assembly [GO:0033962]; RNA splicing [GO:0008380]; spliceosomal snRNP assembly [GO:0000387] GO:0000387; GO:0000398; GO:0000932; GO:0000956; GO:0003723; GO:0005634; GO:0005654; GO:0005688; GO:0005829; GO:0008380; GO:0016020; GO:0017070; GO:0032991; GO:0033962; GO:0042731; GO:0046540; GO:0071005; GO:0097526; GO:0120115 18751 XM_029337401.2 493 579 230 399 242 Q6GQ82 1.11e-174 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 Xenopus laevis (African clawed frog) chromatin remodeling [GO:0006338]; nervous system development [GO:0007399] GO:0000228; GO:0003677; GO:0006338; GO:0007399; GO:0070603 18752 XM_044316588.1 7041 7393 3437 6491 3949 P13619 1.22e-35 ATP synthase F(0) complex subunit B1, mitochondrial (ATP synthase peripheral stalk-membrane subunit b) (ATP synthase subunit b) (ATPase subunit b) Bos taurus (Bovine) proton motive force-driven ATP synthesis [GO:0015986] GO:0000276; GO:0005753; GO:0015078; GO:0015986 18753 XM_044327936.1 101 184 135 447 374 NA NA NA NA NA NA 18754 XM_029328449.2 434 785 26 417 358 Q63665 2.82e-60 Upstream stimulatory factor 2 (Major late transcription factor 2) (Upstream transcription factor 2) Rattus norvegicus (Rat) lactation [GO:0007595]; lipid homeostasis [GO:0055088]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter by glucose [GO:0000432]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000432; GO:0000978; GO:0000981; GO:0003677; GO:0003690; GO:0003700; GO:0005634; GO:0006357; GO:0007595; GO:0042802; GO:0042803; GO:0043425; GO:0043565; GO:0044877; GO:0045893; GO:0045944; GO:0046982; GO:0055088; GO:1990837 18755 XM_044313202.1 0 2 1 3 8 NA NA NA NA NA NA 18756 XM_029342769.2 5384 4740 3030 4280 3964 Q9UNH5 0 Dual specificity protein phosphatase CDC14A (EC 3.1.3.16) (EC 3.1.3.48) (CDC14 cell division cycle 14 homolog A) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; cilium assembly [GO:0060271]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of cytokinesis [GO:0032467]; protein dephosphorylation [GO:0006470]; regulation of exit from mitosis [GO:0007096]; sensory perception of sound [GO:0007605] GO:0000226; GO:0000922; GO:0004722; GO:0004725; GO:0005654; GO:0005730; GO:0005737; GO:0005813; GO:0005829; GO:0006470; GO:0007049; GO:0007096; GO:0007605; GO:0008138; GO:0016604; GO:0017018; GO:0032426; GO:0032467; GO:0051301; GO:0060091; GO:0060271; GO:0072686; GO:1902636 18757 XM_044325410.1 33 0 0 0 0 Q9DBN1 2.84e-29 Stimulated by retinoic acid gene 6 protein-like (STRA6-like protein) (Retinol-binding protein 4 receptor 2) (RBP4 receptor 2) Mus musculus (Mouse) establishment of localization in cell [GO:0051649]; retinol transport [GO:0034633]; vitamin A import into cell [GO:0071939] GO:0005886; GO:0034633; GO:0051649; GO:0071939 18758 XM_044308377.1 340 213 0 0 557 Q9UJX3 1.76e-121 Anaphase-promoting complex subunit 7 (APC7) (Cyclosome subunit 7) Homo sapiens (Human) anaphase-promoting complex-dependent catabolic process [GO:0031145]; brain development [GO:0007420]; cell division [GO:0051301]; metaphase/anaphase transition of mitotic cell cycle [GO:0007091]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; protein K11-linked ubiquitination [GO:0070979]; protein ubiquitination [GO:0016567]; regulation of meiotic cell cycle [GO:0051445]; regulation of mitotic cell cycle [GO:0007346] GO:0000792; GO:0005634; GO:0005654; GO:0005680; GO:0005737; GO:0005819; GO:0005829; GO:0007091; GO:0007346; GO:0007420; GO:0015630; GO:0016567; GO:0019903; GO:0031145; GO:0045842; GO:0051301; GO:0051445; GO:0070979; GO:0140767 18759 XM_044316635.1 176 0 22 145 89 NA NA NA NA NA NA 18760 XM_044309069.1 87 272 74 333 653 Q9N2I7 2.22e-33 Dipeptidyl peptidase 4 (EC 3.4.14.5) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (CD antigen CD26) [Cleaved into: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)] Felis catus (Cat) (Felis silvestris catus) cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; T cell costimulation [GO:0031295] GO:0002020; GO:0004177; GO:0004252; GO:0005102; GO:0005576; GO:0005886; GO:0006508; GO:0007155; GO:0008239; GO:0008284; GO:0009986; GO:0010716; GO:0016324; GO:0030027; GO:0030139; GO:0031258; GO:0031295; GO:0042803; GO:0043542; GO:0045121; GO:0070161 18761 XM_029323668.2 24 0 0 0 0 Q9C0B7 3.87e-132 Transport and Golgi organization protein 6 homolog (Transmembrane and coiled-coil domain-containing protein 7) Homo sapiens (Human) protein secretion [GO:0009306] GO:0009306; GO:0016020 18762 XM_029349491.2 842 420 393 441 230 Q6IRB2 7.11e-38 Transcription factor HES-1-A (Hairy and enhancer of split 1-A) (Protein hairy-1) (Xhairy-1) (Xhairy1) (Xlh1) Xenopus laevis (African clawed frog) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of muscle organ development [GO:0048635]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219] GO:0000122; GO:0005634; GO:0007219; GO:0043425; GO:0043565; GO:0045892; GO:0046982; GO:0048635 18763 XM_044317376.1 210 87 65 176 502 Q7Z020 2.62e-136 Transient receptor potential cation channel subfamily A member 1 (dTRPA1) (Ankyrin-like with transmembrane domains protein 1) (dANKTM1) Drosophila melanogaster (Fruit fly) calcium ion transport [GO:0006816]; cation transport [GO:0006812]; cellular response to heat [GO:0034605]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; detection of temperature stimulus involved in thermoception [GO:0050960]; mechanosensory behavior [GO:0007638]; negative phototaxis [GO:0046957]; neuronal signal transduction [GO:0023041]; phototransduction [GO:0007602]; positive regulation of calcium-mediated signaling [GO:0050850]; response to heat [GO:0009408]; response to light stimulus [GO:0009416]; temperature compensation of the circadian clock [GO:0010378]; thermosensory behavior [GO:0040040]; thermotaxis [GO:0043052] GO:0001580; GO:0005261; GO:0005262; GO:0005886; GO:0006812; GO:0006816; GO:0007602; GO:0007638; GO:0009408; GO:0009416; GO:0010378; GO:0015276; GO:0016020; GO:0023041; GO:0034605; GO:0034703; GO:0040040; GO:0043052; GO:0046957; GO:0050850; GO:0050960; GO:0050965; GO:0050968; GO:0097604 18764 XR_006392324.1 68 14 93 14 173 NA NA NA NA NA NA 18765 XM_044314971.1 0 3 0 26 8 NA NA NA NA NA NA 18766 XM_029334562.2 51 40 39 57 36 Q9BRF8 1.37e-38 Serine/threonine-protein phosphatase CPPED1 (EC 3.1.3.16) (Calcineurin-like phosphoesterase domain-containing protein 1) (Complete S-transactivated protein 1) Homo sapiens (Human) NA GO:0005576; GO:0005829; GO:0005886; GO:0017018; GO:0035578; GO:0046872 18767 XM_029350733.2 1941 2151 1499 3026 2719 Q92539 3.5e-126 Phosphatidate phosphatase LPIN2 (EC 3.1.3.4) (Lipin-2) Homo sapiens (Human) cellular lipid metabolic process [GO:0044255]; cellular response to insulin stimulus [GO:0032869]; fatty acid catabolic process [GO:0009062]; lipid metabolic process [GO:0006629]; positive regulation of transcription by RNA polymerase II [GO:0045944]; triglyceride biosynthetic process [GO:0019432] GO:0003713; GO:0005634; GO:0005789; GO:0005829; GO:0006629; GO:0008195; GO:0009062; GO:0019432; GO:0032869; GO:0044255; GO:0045944 18768 XM_029350733.2 1941 2151 1499 3026 2719 Q92539 4.9e-27 Phosphatidate phosphatase LPIN2 (EC 3.1.3.4) (Lipin-2) Homo sapiens (Human) cellular lipid metabolic process [GO:0044255]; cellular response to insulin stimulus [GO:0032869]; fatty acid catabolic process [GO:0009062]; lipid metabolic process [GO:0006629]; positive regulation of transcription by RNA polymerase II [GO:0045944]; triglyceride biosynthetic process [GO:0019432] GO:0003713; GO:0005634; GO:0005789; GO:0005829; GO:0006629; GO:0008195; GO:0009062; GO:0019432; GO:0032869; GO:0044255; GO:0045944 18769 XM_044325841.1 0 0 0 29 0 NA NA NA NA NA NA 18770 XM_044322249.1 565 88 500 136 372 NA NA NA NA NA NA 18771 XM_044325774.1 28 0 0 0 32 NA NA NA NA NA NA 18772 XM_044310041.1 33 20 17 17 366 O46503 1.44e-55 Sulfotransferase 1C2 (ST1C2) (rabSULT1C2) (EC 2.8.2.1) (Sulfotransferase 1C1) Oryctolagus cuniculus (Rabbit) sulfation [GO:0051923] GO:0004062; GO:0005737; GO:0005764; GO:0051923 18773 XM_044315647.1 148 12 38 25 23 NA NA NA NA NA NA 18774 XM_044308319.1 254 99 56 133 126 Q9UDY8 1.3e-65 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (EC 3.4.22.-) (MALT lymphoma-associated translocation) (Paracaspase) Homo sapiens (Human) activation of NF-kappaB-inducing kinase activity [GO:0007250]; B cell activation [GO:0042113]; B-1 B cell differentiation [GO:0001923]; defense response [GO:0006952]; innate immune response [GO:0045087]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; negative regulation of apoptotic process [GO:0043066]; nuclear export [GO:0051168]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T-helper 17 cell differentiation [GO:2000321]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of apoptotic process [GO:0042981]; regulation of T cell receptor signaling pathway [GO:0050856]; response to fungus [GO:0009620]; T cell proliferation [GO:0042098]; T cell receptor signaling pathway [GO:0050852] GO:0001650; GO:0001923; GO:0002020; GO:0002096; GO:0002726; GO:0004175; GO:0004197; GO:0004842; GO:0005634; GO:0005737; GO:0005829; GO:0006508; GO:0006952; GO:0007250; GO:0008233; GO:0009620; GO:0031398; GO:0031663; GO:0032449; GO:0032731; GO:0032743; GO:0032991; GO:0036094; GO:0042098; GO:0042113; GO:0042802; GO:0042981; GO:0043066; GO:0043123; GO:0043280; GO:0043621; GO:0045087; GO:0048471; GO:0050852; GO:0050856; GO:0051092; GO:0051168; GO:0051603; GO:2000321 18775 XM_029327036.2 2320 1691 1045 1578 2346 Q9GMB8 0 Serine--tRNA ligase, cytoplasmic (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase) Bos taurus (Bovine) cytoplasmic translation [GO:0002181]; negative regulation of angiogenesis [GO:0016525]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular endothelial growth factor production [GO:1904046]; selenocysteine incorporation [GO:0001514]; selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]; seryl-tRNA aminoacylation [GO:0006434] GO:0000049; GO:0000122; GO:0000978; GO:0001514; GO:0002181; GO:0004828; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006434; GO:0016525; GO:0019899; GO:0042803; GO:0097056; GO:0098619; GO:1904046 18776 XM_029328595.2 462 338 220 313 295 Q8C2L6 1.21e-88 Transmembrane protein 161B Mus musculus (Mouse) regulation of cardiac muscle cell action potential [GO:0098901]; regulation of heart rate [GO:0002027] GO:0002027; GO:0005886; GO:0098901 18777 XM_029351856.2 311 18 36 126 219 E7F590 0 Vacuolar protein sorting-associated protein 41 homolog Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to starvation [GO:0009267]; endosomal vesicle fusion [GO:0034058]; endosome to lysosome transport [GO:0008333]; macroautophagy [GO:0016236]; protein targeting to vacuole [GO:0006623] GO:0005765; GO:0005770; GO:0005794; GO:0005829; GO:0006623; GO:0008333; GO:0009267; GO:0016236; GO:0030136; GO:0030897; GO:0031901; GO:0031902; GO:0034058; GO:0046872 18778 XR_006395644.1 3595 1180 704 1609 435 NA NA NA NA NA NA 18779 XR_006396596.1 63 56 50 136 53 NA NA NA NA NA NA 18780 XM_029339369.2 419 106 238 101 212 Q8WXK3 2.72e-55 Ankyrin repeat and SOCS box protein 13 (ASB-13) Homo sapiens (Human) intracellular signal transduction [GO:0035556]; protein ubiquitination [GO:0016567] GO:0005829; GO:0016567; GO:0035556 18781 XM_029343580.2 0 148 287 0 336 Q8R2N1 7.84e-85 Aquaporin-3 (AQP-3) (Aquaglyceroporin-3) Mus musculus (Mouse) cellular response to hypoxia [GO:0071456]; cellular response to oxygen-glucose deprivation [GO:0090650]; establishment of localization in cell [GO:0051649]; glycerol transmembrane transport [GO:0015793]; odontogenesis [GO:0042476]; polyol transmembrane transport [GO:0015791]; positive regulation of immune system process [GO:0002684]; renal water absorption [GO:0070295]; response to retinoic acid [GO:0032526]; urea transport [GO:0015840]; water transport [GO:0006833] GO:0002684; GO:0005654; GO:0005737; GO:0005886; GO:0005911; GO:0006833; GO:0015166; GO:0015204; GO:0015250; GO:0015254; GO:0015791; GO:0015793; GO:0015840; GO:0016323; GO:0032526; GO:0042476; GO:0042802; GO:0051649; GO:0070295; GO:0071456; GO:0090650 18782 XM_029356257.2 3483 3546 1734 2998 1591 NA NA NA NA NA NA 18783 XM_044311501.1 42 10 12 23 55 NA NA NA NA NA NA 18784 XM_044312838.1 186 0 0 459 645 NA NA NA NA NA NA 18785 XM_044318071.1 3 134 43 127 198 NA NA NA NA NA NA 18786 XM_029351843.2 359 62 199 426 227 NA NA NA NA NA NA 18787 XM_029346267.2 5 16 0 0 13 NA NA NA NA NA NA 18788 XM_044308591.1 0 0 5 0 22 Q658G7 8e-21 LRR receptor-like serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (ERECTA homolog 2) (ER homolog 2) (OsER2) (Stress-induced protein kinase 1) (OsSIK1) Oryza sativa subsp. japonica (Rice) positive regulation of response to salt stress [GO:1901002]; positive regulation of response to water deprivation [GO:1902584]; protein phosphorylation [GO:0006468]; regulation of stomatal complex development [GO:2000038] GO:0004675; GO:0005524; GO:0005886; GO:0006468; GO:0106310; GO:1901002; GO:1902584; GO:2000038 18789 XR_006395989.1 33 9 27 15 75 NA NA NA NA NA NA 18790 XM_044327890.1 335 171 201 171 303 Q9DCG9 9.93e-36 Multifunctional methyltransferase subunit TRM112-like protein (tRNA methyltransferase 112 homolog) Mus musculus (Mouse) histone lysine methylation [GO:0034968]; peptidyl-glutamine methylation [GO:0018364]; positive regulation of rRNA processing [GO:2000234]; rRNA (guanine-N7)-methylation [GO:0070476]; rRNA methylation [GO:0031167]; tRNA methylation [GO:0030488]; tRNA N2-guanine methylation [GO:0002940] GO:0002940; GO:0005654; GO:0008276; GO:0018364; GO:0030488; GO:0031167; GO:0032991; GO:0034968; GO:0046982; GO:0048471; GO:0070476; GO:2000234 18791 XM_029336805.2 59 17 0 74 65 P17124 3.62e-24 Histamine H2 receptor (H2R) (HH2R) (Gastric receptor I) Canis lupus familiaris (Dog) (Canis familiaris) chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; gastric acid secretion [GO:0001696]; positive regulation of vasoconstriction [GO:0045907] GO:0001696; GO:0004969; GO:0004993; GO:0005886; GO:0007187; GO:0007268; GO:0030425; GO:0030594; GO:0045202; GO:0045907 18792 XM_029333901.2 3437 3469 673 3214 1727 P43793 0 NADP-specific glutamate dehydrogenase (NADP-GDH) (EC 1.4.1.4) Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) glutamate biosynthetic process [GO:0006537] GO:0004354; GO:0005737; GO:0005829; GO:0006537 18793 XM_044318205.1 9 10 16 5 2 NA NA NA NA NA NA 18794 XM_044315233.1 18 17 7 15 51 NA NA NA NA NA NA 18795 XM_044323115.1 65 33 68 20 61 Q7RTR2 3.04e-26 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 18796 XM_044318858.1 603 437 272 441 734 Q92179 6.45e-31 Carbohydrate sulfotransferase 3 (EC 2.8.2.17) (EC 2.8.2.21) (Chondroitin 6-O-sulfotransferase 1) (C6ST-1) (Chondroitin 6-sulfotransferase) (C6ST) Gallus gallus (Chicken) carbohydrate metabolic process [GO:0005975]; chondroitin sulfate biosynthetic process [GO:0030206]; N-acetylglucosamine metabolic process [GO:0006044]; sulfur compound metabolic process [GO:0006790] GO:0000139; GO:0001517; GO:0005802; GO:0005975; GO:0006044; GO:0006790; GO:0008459; GO:0030206 18797 XM_044318889.1 0 0 0 41 0 NA NA NA NA NA NA 18798 XM_029341279.2 17 13 14 12 177 Q96DM1 3.24e-92 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 18799 XM_044312480.1 5 0 0 7 0 NA NA NA NA NA NA 18800 XM_044321392.1 2 7 4 14 152 P46023 9.77e-91 G-protein coupled receptor GRL101 Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004930; GO:0005886 18801 XR_006393992.1 0 0 1 9 0 NA NA NA NA NA NA 18802 XM_044323461.1 0 2 0 13 0 NA NA NA NA NA NA 18803 XM_029350367.2 2663 1152 1485 1252 1439 NA NA NA NA NA NA 18804 XM_029337296.2 472 664 575 924 373 Q8C9A2 1.02e-91 Endonuclease V (EC 3.1.26.-) Mus musculus (Mouse) DNA repair [GO:0006281] GO:0000287; GO:0003677; GO:0003727; GO:0005730; GO:0005737; GO:0006281; GO:0010494; GO:0016888; GO:0016891 18805 XM_044312435.1 0 0 0 8 0 NA NA NA NA NA NA 18806 XM_044316335.1 843 47 26 1038 673 Q55EC7 1.64e-27 RasGEF domain-containing serine/threonine-protein kinase X (EC 2.7.11.1) (Ras guanine nucleotide exchange factor X) (RasGEF domain-containing protein X) Dictyostelium discoideum (Social amoeba) protein phosphorylation [GO:0006468]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264] GO:0004672; GO:0004674; GO:0005085; GO:0005524; GO:0005737; GO:0006468; GO:0007165; GO:0007264; GO:0106310 18807 XM_029329443.2 1698 1523 913 1314 1871 Q99LU8 2.51e-92 Uncharacterized protein C6orf62 homolog Mus musculus (Mouse) NA NA 18808 XM_044318151.1 616 373 285 540 561 Q8BLA8 1.64e-126 Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Wasabi receptor) Mus musculus (Mouse) calcium ion transmembrane import into cytosol [GO:0097553]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cell surface receptor signaling pathway [GO:0007166]; cellular calcium ion homeostasis [GO:0006874]; cellular response to carbon dioxide [GO:0071244]; cellular response to cold [GO:0070417]; cellular response to heat [GO:0034605]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to organic substance [GO:0071310]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; positive regulation of anion transport [GO:1903793]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of sensory perception of pain [GO:1904058]; protein homotetramerization [GO:0051289]; regulation of blood circulation [GO:1903522]; regulation of neuronal action potential [GO:0098908]; response to cold [GO:0009409]; response to hydrogen peroxide [GO:0042542]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; sensory perception of pain [GO:0019233]; thermoception [GO:0050955]; urinary bladder smooth muscle contraction [GO:0014832] GO:0005216; GO:0005245; GO:0005262; GO:0005886; GO:0006816; GO:0006874; GO:0007166; GO:0009409; GO:0009410; GO:0010033; GO:0014070; GO:0014832; GO:0015267; GO:0015278; GO:0016020; GO:0016324; GO:0019233; GO:0030424; GO:0032421; GO:0034605; GO:0035774; GO:0042542; GO:0042802; GO:0048265; GO:0050955; GO:0050966; GO:0050968; GO:0050974; GO:0051289; GO:0070301; GO:0070417; GO:0070588; GO:0071244; GO:0071310; GO:0097553; GO:0097604; GO:0098908; GO:1903522; GO:1903793; GO:1904058; GO:1990760 18809 XM_029346947.2 1347 1892 1407 2574 2373 Q0V8S0 5.21e-132 Hepatocyte growth factor-regulated tyrosine kinase substrate Bos taurus (Bovine) endocytic recycling [GO:0032456]; membrane invagination [GO:0010324]; negative regulation of angiogenesis [GO:0016525]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of gene expression [GO:0010628]; protein localization to membrane [GO:0072657]; protein targeting to lysosome [GO:0006622]; receptor internalization [GO:0031623]; regulation of MAP kinase activity [GO:0043405] GO:0005764; GO:0005769; GO:0005829; GO:0006622; GO:0010324; GO:0010628; GO:0010642; GO:0016525; GO:0019904; GO:0030948; GO:0031623; GO:0031901; GO:0032456; GO:0032585; GO:0033565; GO:0035091; GO:0043130; GO:0043405; GO:0044389; GO:0046426; GO:0046872; GO:0072657; GO:1903543 18810 XM_044326393.1 995 880 1483 3064 2780 Q02858 1.59e-76 Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (HYK) (STK1) (Tunica interna endothelial cell kinase) (Tyrosine kinase with Ig and EGF homology domains-2) (Tyrosine-protein kinase receptor TEK) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (p140 TEK) (CD antigen CD202b) Mus musculus (Mouse) angiogenesis [GO:0001525]; branching involved in blood vessel morphogenesis [GO:0001569]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; endothelial cell proliferation [GO:0001935]; glomerulus vasculature development [GO:0072012]; heart development [GO:0007507]; heart trabecula formation [GO:0060347]; hemopoiesis [GO:0030097]; negative regulation of angiogenesis [GO:0016525]; negative regulation of apoptotic process [GO:0043066]; negative regulation of endothelial cell apoptotic process [GO:2000352]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein autophosphorylation [GO:0046777]; regulation of angiogenesis [GO:0045765]; regulation of cell migration [GO:0030334]; regulation of endothelial cell proliferation [GO:0001936]; regulation of establishment or maintenance of cell polarity [GO:0032878]; regulation of NIK/NF-kappaB signaling [GO:1901222]; response to estrogen [GO:0043627]; response to hypoxia [GO:0001666]; response to retinoic acid [GO:0032526]; sprouting angiogenesis [GO:0002040]; substrate adhesion-dependent cell spreading [GO:0034446]; Tie signaling pathway [GO:0048014]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570] GO:0001525; GO:0001569; GO:0001570; GO:0001666; GO:0001725; GO:0001934; GO:0001935; GO:0001936; GO:0002040; GO:0002720; GO:0004713; GO:0004714; GO:0005524; GO:0005576; GO:0005884; GO:0005886; GO:0005902; GO:0005911; GO:0005925; GO:0007160; GO:0007169; GO:0007507; GO:0009925; GO:0009986; GO:0010595; GO:0014068; GO:0016020; GO:0016323; GO:0016324; GO:0016525; GO:0018108; GO:0019838; GO:0030097; GO:0030334; GO:0030949; GO:0032526; GO:0032878; GO:0033138; GO:0033674; GO:0034446; GO:0034451; GO:0038023; GO:0042307; GO:0042802; GO:0043066; GO:0043235; GO:0043410; GO:0043552; GO:0043627; GO:0045121; GO:0045765; GO:0045766; GO:0045785; GO:0046777; GO:0048014; GO:0048471; GO:0051894; GO:0051897; GO:0060347; GO:0070374; GO:0072012; GO:0098609; GO:1901222; GO:1902533; GO:2000251; GO:2000352 18811 XM_044323885.1 42 40 211 493 10 NA NA NA NA NA NA 18812 XM_044315817.1 785 606 288 566 823 Q6DCE3 1.2e-128 Proton-coupled zinc antiporter SLC30A9, mitochondrial (Solute carrier family 30 member 9) (Zinc transporter 9) (ZnT-9) Xenopus laevis (African clawed frog) cellular zinc ion homeostasis [GO:0006882]; zinc ion transport [GO:0006829] GO:0005634; GO:0005783; GO:0006829; GO:0006882; GO:0008324; GO:0016020; GO:0031410 18813 XM_029325901.2 163 184 90 135 140 NA NA NA NA NA NA 18814 XR_006396713.1 0 22 0 66 0 NA NA NA NA NA NA 18815 XR_006391576.1 832 1132 958 1539 484 NA NA NA NA NA NA 18816 XM_029337614.2 0 0 2 11 0 NA NA NA NA NA NA 18817 XR_003824337.2 56 61 44 27 68 NA NA NA NA NA NA 18818 XM_044327797.1 3 39 8 29 5 NA NA NA NA NA NA 18819 XM_044318932.1 0 0 0 0 29 P70196 6.82e-32 TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6) Mus musculus (Mouse) activation of NF-kappaB-inducing kinase activity [GO:0007250]; activation of protein kinase activity [GO:0032147]; animal organ morphogenesis [GO:0009887]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; bone remodeling [GO:0046849]; bone resorption [GO:0045453]; cell development [GO:0048468]; cellular response to cytokine stimulus [GO:0071345]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-17-mediated signaling pathway [GO:0097400]; JNK cascade [GO:0007254]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin production [GO:0002637]; response to interleukin-1 [GO:0070555]; signal transduction [GO:0007165]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000122; GO:0000209; GO:0001503; GO:0001701; GO:0001843; GO:0002637; GO:0002726; GO:0004842; GO:0005164; GO:0005634; GO:0005737; GO:0005811; GO:0005829; GO:0005886; GO:0005938; GO:0006955; GO:0006974; GO:0007165; GO:0007249; GO:0007250; GO:0007254; GO:0008270; GO:0009887; GO:0009898; GO:0016567; GO:0019221; GO:0019886; GO:0019901; GO:0030316; GO:0031435; GO:0031624; GO:0031625; GO:0031663; GO:0031666; GO:0031996; GO:0032147; GO:0032735; GO:0032743; GO:0032755; GO:0032813; GO:0032991; GO:0033209; GO:0035631; GO:0042088; GO:0042102; GO:0042475; GO:0042802; GO:0042826; GO:0042981; GO:0043011; GO:0043122; GO:0043123; GO:0043422; GO:0043507; GO:0045453; GO:0045672; GO:0045892; GO:0045944; GO:0046330; GO:0046849; GO:0047485; GO:0048468; GO:0048471; GO:0048661; GO:0050852; GO:0051091; GO:0051092; GO:0051865; GO:0061630; GO:0070498; GO:0070534; GO:0070555; GO:0071222; GO:0071345; GO:0097400; GO:1901224; GO:1904996; GO:2000679 18820 XR_006393027.1 75 125 94 45 272 NA NA NA NA NA NA 18821 XM_029339527.2 0 10 1 14 3 G3M4F8 2.12e-23 Octopamine receptor beta-2R (CsOA2B2) Chilo suppressalis (Asiatic rice borer moth) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cellular response to amine stimulus [GO:0071418]; octopamine signaling pathway [GO:0071927]; tyramine signaling pathway [GO:0071928] GO:0004989; GO:0005886; GO:0007189; GO:0008226; GO:0016020; GO:0071418; GO:0071927; GO:0071928 18822 XR_006394118.1 10 0 24 0 80 NA NA NA NA NA NA 18823 XM_044306888.1 25 0 5 1 47 NA NA NA NA NA NA 18824 XM_029354875.2 6 22 5 49 0 NA NA NA NA NA NA 18825 XR_006393111.1 226 311 190 1855 1112 NA NA NA NA NA NA 18826 XR_006393373.1 74 37 46 31 29 NA NA NA NA NA NA 18827 XR_006394494.1 0 0 0 0 9 NA NA NA NA NA NA 18828 XM_029356967.2 855 483 503 926 991 Q7Z5Y7 2.61e-126 BTB/POZ domain-containing protein KCTD20 (Potassium channel tetramerization domain containing 20) Homo sapiens (Human) positive regulation of phosphorylation [GO:0042327] GO:0005737; GO:0042327 18829 XM_044328469.1 11 12 22 0 22 Q9EQC4 4.47e-62 Elongation of very long chain fatty acids protein 4 (EC 2.3.1.199) (3-keto acyl-CoA synthase Elovl4) (ELOVL fatty acid elongase 4) (ELOVL FA elongase 4) (Very long chain 3-ketoacyl-CoA synthase 4) (Very long chain 3-oxoacyl-CoA synthase 4) Mus musculus (Mouse) fatty acid elongation, monounsaturated fatty acid [GO:0034625]; fatty acid elongation, polyunsaturated fatty acid [GO:0034626]; fatty acid elongation, saturated fatty acid [GO:0019367]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; sphingolipid biosynthetic process [GO:0030148]; unsaturated fatty acid biosynthetic process [GO:0006636]; very long-chain fatty acid biosynthetic process [GO:0042761] GO:0005783; GO:0005789; GO:0006636; GO:0009922; GO:0019367; GO:0030148; GO:0034625; GO:0034626; GO:0035338; GO:0042761; GO:0102756 18830 XM_029338795.2 278 209 193 387 241 P55214 4.69e-60 Caspase-7 (CASP-7) (EC 3.4.22.60) (Apoptotic protease Mch-3) (ICE-like apoptotic protease 3) (ICE-LAP3) (SREBP cleavage activity 2) (SCA-2) [Cleaved into: Caspase-7 subunit p20; Caspase-7 subunit p11] Mesocricetus auratus (Golden hamster) defense response to bacterium [GO:0042742]; intracellular signal transduction [GO:0035556]; lymphocyte apoptotic process [GO:0070227]; positive regulation of plasma membrane repair [GO:1905686]; proteolysis [GO:0006508] GO:0003723; GO:0004190; GO:0005615; GO:0005634; GO:0005737; GO:0005829; GO:0006508; GO:0035556; GO:0042742; GO:0070227; GO:0097153; GO:1905686 18831 XM_029325009.2 1882 1243 1141 2182 2062 Q25197 0 Putative insulin-like peptide receptor (EC 2.7.10.1) Hydra vulgaris (Hydra) (Hydra attenuata) protein autophosphorylation [GO:0046777]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0004714; GO:0005524; GO:0007169; GO:0016020; GO:0043548; GO:0043560; GO:0046777; GO:0046872 18832 XM_029333625.2 337 321 78 376 296 NA NA NA NA NA NA 18833 XM_044310608.1 731 341 309 657 522 NA NA NA NA NA NA 18834 XM_044307048.1 0 0 0 6 11 NA NA NA NA NA NA 18835 XM_029328699.2 562 846 380 452 462 Q6PCS6 3.14e-41 Mitochondrial fission process protein 1 (Mitochondrial 18 kDa protein) (MTP18) Danio rerio (Zebrafish) (Brachydanio rerio) apoptotic process [GO:0006915]; mitochondrial fission [GO:0000266] GO:0000266; GO:0005739; GO:0005743; GO:0006915 18836 XR_006395015.1 314 234 65 566 212 NA NA NA NA NA NA 18837 XR_006393789.1 1 20 82 5 9 NA NA NA NA NA NA 18838 XM_044314866.1 153 43 122 159 163 E9PVD1 3.51e-68 Coiled-coil domain-containing protein 62 Mus musculus (Mouse) blastocyst hatching [GO:0001835]; cellular response to estradiol stimulus [GO:0071392]; positive regulation of transcription by RNA polymerase II [GO:0045944]; spermatid development [GO:0007286] GO:0001669; GO:0001835; GO:0005634; GO:0005654; GO:0005886; GO:0007286; GO:0030331; GO:0030374; GO:0045944; GO:0071392 18839 XM_029348038.2 1320 724 853 1230 1524 Q5RD78 0 Probable E3 ubiquitin-protein ligase HECTD2 (EC 2.3.2.26) (HECT domain-containing protein 2) (HECT-type E3 ubiquitin transferase HECTD2) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) protein polyubiquitination [GO:0000209] GO:0000209; GO:0061630 18840 XR_006397979.1 65 27 88 85 115 NA NA NA NA NA NA 18841 XM_044321187.1 321 330 283 364 697 NA NA NA NA NA NA 18842 XM_029350639.2 456 237 330 343 302 Q9SB50 2.79e-122 AP-4 complex subunit mu (Adaptor protein complex AP-4 subunit mu) (Adaptor protein-4 mu-adaptin) (Adaptor-related protein complex 4 subunit mu) (At-muC-Ad) (Mu4-adaptin) Arabidopsis thaliana (Mouse-ear cress) Golgi to lysosome transport [GO:0090160]; protein targeting [GO:0006605]; vesicle-mediated transport [GO:0016192] GO:0005802; GO:0005829; GO:0005905; GO:0006605; GO:0016192; GO:0030124; GO:0030131; GO:0031410; GO:0090160 18843 XM_044322786.1 40 12 26 13 32 O54991 3.08e-34 Contactin-associated protein 1 (Caspr) (Caspr1) (MHDNIV) (NCP1) (Neurexin IV) (Neurexin-4) (Paranodin) Mus musculus (Mouse) axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cytoskeleton organization [GO:0007010]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process [GO:0050905]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuronal action potential propagation [GO:0019227]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; postsynaptic density organization [GO:0097106]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; regulation of synapse maturation [GO:0090128] GO:0002175; GO:0005886; GO:0005918; GO:0007005; GO:0007010; GO:0007155; GO:0007409; GO:0016020; GO:0017124; GO:0019227; GO:0022010; GO:0022011; GO:0030424; GO:0030913; GO:0031175; GO:0033010; GO:0033270; GO:0042552; GO:0043209; GO:0048786; GO:0048812; GO:0050884; GO:0050885; GO:0050905; GO:0071205; GO:0090128; GO:0097106; GO:0098529; GO:0098978; GO:1990227 18844 XM_044316778.1 85 65 55 160 84 Q61824 5.66e-135 Disintegrin and metalloproteinase domain-containing protein 12 (ADAM 12) (EC 3.4.24.-) (Meltrin-alpha) Mus musculus (Mouse) cell adhesion [GO:0007155]; positive regulation of angiogenesis [GO:0045766]; proteolysis [GO:0006508] GO:0004222; GO:0005654; GO:0005886; GO:0006508; GO:0007155; GO:0017124; GO:0045766; GO:0046872 18845 XM_029336422.2 32 13 85 48 39 NA NA NA NA NA NA 18846 XR_006392643.1 0 29 1 0 0 NA NA NA NA NA NA 18847 XM_029326873.2 259 361 97 277 210 Q5XGI0 0 Ribose-phosphate pyrophosphokinase 2 (EC 2.7.6.1) (Phosphoribosyl pyrophosphate synthase II) (PRS-II) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) 5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleotide biosynthetic process [GO:0009165]; phosphorylation [GO:0016310]; ribonucleoside monophosphate biosynthetic process [GO:0009156] GO:0000287; GO:0004749; GO:0005524; GO:0006015; GO:0009156; GO:0009165; GO:0016301; GO:0016310; GO:0042803 18848 XM_044309602.1 41 0 0 113 0 Q96DM1 3.78e-63 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 18849 XM_029357598.2 0 0 1 9 0 NA NA NA NA NA NA 18850 XR_006396201.1 589 825 681 665 250 NA NA NA NA NA NA 18851 XM_029334429.2 5882 4607 3295 3853 2961 Q6PBU5 1.57e-105 Growth hormone-regulated TBC protein 1-A Danio rerio (Zebrafish) (Brachydanio rerio) activation of GTPase activity [GO:0090630] GO:0005096; GO:0090630 18852 XM_044324974.1 0 4 8 0 9 NA NA NA NA NA NA 18853 XM_029339955.2 96 288 109 390 105 NA NA NA NA NA NA 18854 XM_029347091.2 62 104 73 160 135 NA NA NA NA NA NA 18855 XR_006396410.1 0 27 15 30 0 NA NA NA NA NA NA 18856 XR_003827573.2 4 198 2 9 174 NA NA NA NA NA NA 18857 XM_029332417.2 163 141 38 102 163 NA NA NA NA NA NA 18858 XM_044319201.1 0 3 9 29 25 P26221 1.97e-112 Endoglucanase E-4 (EC 3.2.1.4) (Cellulase E-4) (Cellulase E4) (Endo-1,4-beta-glucanase E-4) Thermobifida fusca (Thermomonospora fusca) cellulose catabolic process [GO:0030245] GO:0008810; GO:0030245; GO:0030248 18859 XM_044324157.1 301 212 190 284 578 A0A0R4IB93 0 NA NA NA NA 18860 XM_044324157.1 301 212 190 284 578 A0A0R4IB93 4.38e-35 NA NA NA NA 18861 XR_006394479.1 0 0 0 0 23 NA NA NA NA NA NA 18862 XM_044315102.1 7 48 5 21 24 NA NA NA NA NA NA 18863 XM_044309392.1 26 0 10 0 20 NA NA NA NA NA NA 18864 XR_006393413.1 172 101 21 110 46 NA NA NA NA NA NA 18865 XM_029331890.2 3352 3187 2559 3613 3935 P49841 0 Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1) Homo sapiens (Human) beta-catenin destruction complex disassembly [GO:1904886]; cellular response to amyloid-beta [GO:1904646]; cellular response to interleukin-3 [GO:0036016]; cellular response to retinoic acid [GO:0071300]; circadian rhythm [GO:0007623]; dopamine receptor signaling pathway [GO:0007212]; epithelial to mesenchymal transition [GO:0001837]; ER overload response [GO:0006983]; establishment of cell polarity [GO:0030010]; excitatory postsynaptic potential [GO:0060079]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; glycogen metabolic process [GO:0005977]; heart valve development [GO:0003170]; hippocampus development [GO:0021766]; insulin receptor signaling pathway [GO:0008286]; intracellular signal transduction [GO:0035556]; maintenance of cell polarity [GO:0030011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of canonical Wnt signaling pathway involved in osteoblast differentiation [GO:1905240]; negative regulation of dopaminergic neuron differentiation [GO:1904339]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of gene expression [GO:0010629]; negative regulation of glycogen (starch) synthase activity [GO:2000466]; negative regulation of glycogen biosynthetic process [GO:0045719]; negative regulation of mesenchymal stem cell differentiation [GO:2000740]; negative regulation of neuron death [GO:1901215]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein binding [GO:0032091]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of type B pancreatic cell development [GO:2000077]; neuron projection development [GO:0031175]; neuron projection organization [GO:0106027]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of autophagy [GO:0010508]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cilium assembly [GO:0045724]; positive regulation of gene expression [GO:0010628]; positive regulation of GTPase activity [GO:0043547]; positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901030]; positive regulation of mitochondrion organization [GO:0010822]; positive regulation of neuron death [GO:1901216]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein binding [GO:0032092]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein localization to centrosome [GO:1904781]; positive regulation of protein localization to cilium [GO:1903566]; positive regulation of protein-containing complex assembly [GO:0031334]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of axon extension [GO:0030516]; regulation of axonogenesis [GO:0050770]; regulation of cellular response to heat [GO:1900034]; regulation of circadian rhythm [GO:0042752]; regulation of dendrite morphogenesis [GO:0048814]; regulation of long-term synaptic potentiation [GO:1900271]; regulation of microtubule anchoring at centrosome [GO:0150101]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of microtubule-based process [GO:0032886]; regulation of neuron projection development [GO:0010975]; regulation of protein export from nucleus [GO:0046825]; signal transduction [GO:0007165]; superior temporal gyrus development [GO:0071109]; viral protein processing [GO:0019082] GO:0001837; GO:0001954; GO:0002020; GO:0002039; GO:0003170; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005813; GO:0005829; GO:0005886; GO:0005977; GO:0006468; GO:0006983; GO:0007165; GO:0007212; GO:0007623; GO:0008013; GO:0008286; GO:0010508; GO:0010628; GO:0010629; GO:0010822; GO:0010975; GO:0016301; GO:0018105; GO:0018107; GO:0019082; GO:0019901; GO:0021766; GO:0030010; GO:0030011; GO:0030424; GO:0030425; GO:0030516; GO:0030877; GO:0031175; GO:0031333; GO:0031334; GO:0031625; GO:0032091; GO:0032092; GO:0032436; GO:0032515; GO:0032886; GO:0034236; GO:0034452; GO:0035556; GO:0036016; GO:0042752; GO:0043066; GO:0043161; GO:0043547; GO:0045597; GO:0045719; GO:0045724; GO:0045732; GO:0046777; GO:0046825; GO:0046827; GO:0048156; GO:0048814; GO:0050321; GO:0050770; GO:0051059; GO:0060079; GO:0061629; GO:0070507; GO:0070885; GO:0071109; GO:0071300; GO:0090090; GO:0097191; GO:0097192; GO:0098793; GO:0098794; GO:0098978; GO:0099171; GO:0106027; GO:0106310; GO:0150101; GO:1900034; GO:1900181; GO:1900271; GO:1901030; GO:1901215; GO:1901216; GO:1901984; GO:1902042; GO:1903566; GO:1904339; GO:1904646; GO:1904781; GO:1904886; GO:1905240; GO:1990909; GO:2000077; GO:2000466; GO:2000740 18866 XM_029333785.2 644 690 347 805 736 Q6IR75 0 COP9 signalosome complex subunit 2 (Signalosome subunit 2) Xenopus laevis (African clawed frog) NA GO:0005737; GO:0008180 18867 XM_029330571.2 0 0 0 0 97 A0A3Q2HW92 4.7e-119 Major facilitator superfamily domain-containing protein 12 Equus caballus (Horse) carbohydrate transport [GO:0008643]; cysteine transmembrane transport [GO:1903712]; melanin biosynthetic process [GO:0042438]; negative regulation of melanin biosynthetic process [GO:0048022]; pigment metabolic process involved in pigmentation [GO:0043474] GO:0005764; GO:0005765; GO:0005770; GO:0008643; GO:0015293; GO:0033162; GO:0033229; GO:0042438; GO:0043474; GO:0048022; GO:1903712 18868 XM_029328892.2 863 733 229 853 419 P11531 9.19e-106 Dystrophin Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; aging [GO:0007568]; cardiac muscle cell action potential [GO:0086001]; cardiac muscle contraction [GO:0060048]; cerebral cortex development [GO:0021987]; establishment of blood-nerve barrier [GO:0008065]; establishment of glial blood-brain barrier [GO:0060857]; muscle cell cellular homeostasis [GO:0046716]; muscle cell development [GO:0055001]; muscle organ development [GO:0007517]; myotube cell development [GO:0014904]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of peptidyl-cysteine S-nitrosylation [GO:1902083]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; neuron development [GO:0048666]; neuron projection morphogenesis [GO:0048812]; neurotransmitter receptor metabolic process [GO:0045213]; nucleus localization [GO:0051647]; olfactory nerve structural organization [GO:0021629]; peptide biosynthetic process [GO:0043043]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neuron projection development [GO:0010976]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; protein localization [GO:0008104]; protein-containing complex assembly [GO:0065003]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell cycle [GO:0051726]; regulation of cellular response to growth factor stimulus [GO:0090287]; regulation of DNA-templated transcription [GO:0006355]; regulation of gene expression [GO:0010468]; regulation of heart rate [GO:0002027]; regulation of membrane potential [GO:0042391]; regulation of muscle system process [GO:0090257]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of skeletal muscle contraction [GO:0014819]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; regulation of voltage-gated calcium channel activity [GO:1901385]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; response to muscle stretch [GO:0035994]; response to water deprivation [GO:0009414]; skeletal muscle tissue development [GO:0007519]; skeletal muscle tissue regeneration [GO:0043403] GO:0001954; GO:0002027; GO:0002162; GO:0003779; GO:0005178; GO:0005521; GO:0005634; GO:0005741; GO:0005794; GO:0005840; GO:0005883; GO:0005886; GO:0006355; GO:0007517; GO:0007519; GO:0007568; GO:0008065; GO:0008104; GO:0008270; GO:0008284; GO:0008307; GO:0009414; GO:0009986; GO:0010468; GO:0010880; GO:0010881; GO:0010976; GO:0014069; GO:0014809; GO:0014819; GO:0014894; GO:0014904; GO:0016010; GO:0017022; GO:0017166; GO:0021629; GO:0021987; GO:0030016; GO:0030018; GO:0030027; GO:0030036; GO:0030054; GO:0030055; GO:0030141; GO:0030165; GO:0030175; GO:0030424; GO:0030672; GO:0030864; GO:0031527; GO:0032991; GO:0033137; GO:0035994; GO:0042383; GO:0042391; GO:0042995; GO:0043005; GO:0043025; GO:0043034; GO:0043043; GO:0043403; GO:0044306; GO:0044877; GO:0045121; GO:0045202; GO:0045211; GO:0045213; GO:0045665; GO:0045666; GO:0046716; GO:0048471; GO:0048666; GO:0048812; GO:0050998; GO:0051015; GO:0051647; GO:0051726; GO:0055001; GO:0060048; GO:0060314; GO:0060857; GO:0065003; GO:0070373; GO:0086001; GO:0090257; GO:0090287; GO:0097449; GO:0099572; GO:0099617; GO:1901385; GO:1902083; GO:2000651 18869 XM_029337708.2 839 528 387 196 515 O60235 2.12e-52 Transmembrane protease serine 11D (EC 3.4.21.-) (Airway trypsin-like protease) [Cleaved into: Transmembrane protease serine 11D non-catalytic chain; Transmembrane protease serine 11D catalytic chain] Homo sapiens (Human) proteolysis [GO:0006508]; respiratory gaseous exchange by respiratory system [GO:0007585] GO:0004252; GO:0005576; GO:0005886; GO:0006508; GO:0007585; GO:0008233; GO:0070062 18870 XM_044313323.1 1 1 0 0 78 NA NA NA NA NA NA 18871 XM_029348699.2 0 0 23 53 0 Q9D787 0 RING-type E3 ubiquitin-protein ligase PPIL2 (EC 2.3.2.27) (CYC4) (Probable inactive peptidyl-prolyl cis-trans isomerase-like 2) (PPIase) Mus musculus (Mouse) protein folding [GO:0006457]; protein localization to plasma membrane [GO:0072659]; protein peptidyl-prolyl isomerization [GO:0000413]; protein polyubiquitination [GO:0000209] GO:0000209; GO:0000413; GO:0003755; GO:0004842; GO:0005634; GO:0005654; GO:0005737; GO:0005886; GO:0006457; GO:0034450; GO:0061630; GO:0071013; GO:0072659 18872 XM_029335028.2 634 713 485 498 488 Q5ZM55 2.97e-147 Protein fem-1 homolog B (FEM1b) (FEM1-beta) Gallus gallus (Chicken) apoptotic process [GO:0006915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of DNA damage checkpoint [GO:2000001]; ubiquitin-dependent protein catabolic process via the C-end degron rule pathway [GO:0140627] GO:0005634; GO:0005737; GO:0006915; GO:0016567; GO:0031462; GO:0043161; GO:0140627; GO:1990756; GO:2000001 18873 XM_044316803.1 136 69 70 84 98 Q64077 4.75e-25 Substance-K receptor (SKR) (NK-2 receptor) (NK-2R) (Neurokinin A receptor) (Tachykinin receptor 2) Cavia porcellus (Guinea pig) positive regulation of flagellated sperm motility [GO:1902093]; regulation of uterine smooth muscle contraction [GO:0070472] GO:0004995; GO:0005886; GO:0061827; GO:0070472; GO:0097225; GO:1902093 18874 XR_006397243.1 23 0 0 0 1 NA NA NA NA NA NA 18875 XM_029335573.2 10448 21201 9804 14345 12499 Q9V9N4 2.09e-40 NA NA NA NA 18876 XM_029335573.2 10448 21201 9804 14345 12499 Q9V9N4 7.73e-23 NA NA NA NA 18877 XM_044311032.1 48 47 59 105 84 NA NA NA NA NA NA 18878 XR_006392516.1 33 0 20 4 98 NA NA NA NA NA NA 18879 XR_006393151.1 2 16 0 20 23 NA NA NA NA NA NA 18880 XM_029325019.2 1571 1705 1053 2593 2130 Q7ZZL8 7.4e-29 LHFPL tetraspan subfamily member 5 protein (Lipoma HMGIC fusion partner-like 5 protein) (Peripheral myelin protein 22a) Gallus gallus (Chicken) detection of mechanical stimulus involved in sensory perception [GO:0050974]; sensory perception of sound [GO:0007605] GO:0005886; GO:0007605; GO:0016020; GO:0050974 18881 XR_006397858.1 0 0 0 3 10 P70490 1.83e-23 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 18882 XR_006397858.1 0 0 0 3 10 P70490 1.83e-23 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 18883 XM_029349080.2 10213 10881 5202 8165 5071 Q63073 1.95e-38 Protein BTG1 (Anti-proliferative factor) (B-cell translocation gene 1 protein) Rattus norvegicus (Rat) cell population proliferation [GO:0008283]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of mitotic cell cycle [GO:0045930]; positive regulation of angiogenesis [GO:0045766]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of fibroblast apoptotic process [GO:2000271]; positive regulation of myoblast differentiation [GO:0045663]; protein methylation [GO:0006479]; response to oxidative stress [GO:0006979]; response to peptide hormone [GO:0043434]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283] GO:0005634; GO:0005737; GO:0006479; GO:0006979; GO:0007283; GO:0007286; GO:0008283; GO:0008285; GO:0019899; GO:0043434; GO:0045603; GO:0045663; GO:0045766; GO:0045930; GO:2000271 18884 XM_044316828.1 310 677 460 887 656 Q96RW7 6.96e-58 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 18885 XM_044316828.1 310 677 460 887 656 Q96RW7 7.14e-53 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 18886 XM_044316828.1 310 677 460 887 656 Q96RW7 2.19e-31 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 18887 XM_044318465.1 18 110 0 96 0 NA NA NA NA NA NA 18888 XM_029341298.2 4988 4494 2502 3594 1978 P25788 9.63e-133 Proteasome subunit alpha type-3 (Macropain subunit C8) (Multicatalytic endopeptidase complex subunit C8) (Proteasome component C8) Homo sapiens (Human) proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of endopeptidase activity [GO:0052548] GO:0000502; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005839; GO:0010498; GO:0019773; GO:0031625; GO:0043161; GO:0045202; GO:0052548; GO:0070062 18889 XM_029344936.2 21 30 9 105 46 Q54WT7 9.72e-32 Cystinosin homolog Dictyostelium discoideum (Social amoeba) L-cystine transport [GO:0015811] GO:0005765; GO:0005774; GO:0015184; GO:0015293; GO:0015811 18890 XM_029329656.2 715 725 422 787 941 Q6DBU5 0 Mannose-1-phosphate guanyltransferase beta (EC 2.7.7.13) (GDP-mannose pyrophosphorylase B) (GTP-mannose-1-phosphate guanylyltransferase beta) Danio rerio (Zebrafish) (Brachydanio rerio) GDP-mannose biosynthetic process [GO:0009298]; protein glycosylation [GO:0006486] GO:0004475; GO:0005525; GO:0005737; GO:0006486; GO:0009298; GO:0016779 18891 XM_044313044.1 0 1 7 4 21 NA NA NA NA NA NA 18892 XM_029334187.2 1950 1653 1107 1905 1767 NA NA NA NA NA NA 18893 XM_029331501.2 131 260 102 95 176 Q5E9S8 3.19e-96 CDAN1-interacting nuclease 1 Bos taurus (Bovine) erythrocyte differentiation [GO:0030218] GO:0005634; GO:0005737; GO:0030218 18894 XM_029334800.2 0 5 119 106 189 G3M4F8 1.08e-45 Octopamine receptor beta-2R (CsOA2B2) Chilo suppressalis (Asiatic rice borer moth) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cellular response to amine stimulus [GO:0071418]; octopamine signaling pathway [GO:0071927]; tyramine signaling pathway [GO:0071928] GO:0004989; GO:0005886; GO:0007189; GO:0008226; GO:0016020; GO:0071418; GO:0071927; GO:0071928 18895 XM_044319000.1 166 345 39 391 509 Q9BXB4 0 Oxysterol-binding protein-related protein 11 (ORP-11) (OSBP-related protein 11) Homo sapiens (Human) fat cell differentiation [GO:0045444]; positive regulation of sequestering of triglyceride [GO:0010890] GO:0005654; GO:0005794; GO:0005829; GO:0010890; GO:0015248; GO:0016020; GO:0031902; GO:0032934; GO:0043231; GO:0045444 18896 XM_029330767.2 161 109 25 100 99 D3ZR10 2.1e-26 Doublecortin domain-containing protein 2 Rattus norvegicus (Rat) cilium assembly [GO:0060271]; dendrite morphogenesis [GO:0048813]; intracellular signal transduction [GO:0035556]; neuron migration [GO:0001764]; neuronal action potential [GO:0019228]; positive regulation of smoothened signaling pathway [GO:0045880]; regulation of cilium assembly [GO:1902017]; regulation of Wnt signaling pathway [GO:0030111]; sensory perception of sound [GO:0007605]; synaptic transmission, glutamatergic [GO:0035249]; visual learning [GO:0008542] GO:0001764; GO:0005737; GO:0005815; GO:0005829; GO:0005856; GO:0005874; GO:0005929; GO:0005930; GO:0007605; GO:0008542; GO:0019228; GO:0019894; GO:0030111; GO:0034451; GO:0035249; GO:0035556; GO:0045202; GO:0045880; GO:0048813; GO:0060091; GO:0060271; GO:0072686; GO:1902017 18897 XM_029358256.2 534 345 465 391 470 Q9NXS3 3.5e-180 Kelch-like protein 28 (BTB/POZ domain-containing protein 5) Homo sapiens (Human) NA NA 18898 XM_044320127.1 92 117 59 90 78 Q9JI70 3.25e-69 Molecular chaperone MKKS (McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin) (Protein Bbs6 homolog) Mus musculus (Mouse) artery smooth muscle contraction [GO:0014824]; brain morphogenesis [GO:0048854]; cartilage development [GO:0051216]; cerebral cortex development [GO:0021987]; chaperone-mediated protein complex assembly [GO:0051131]; cilium assembly [GO:0060271]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; developmental process [GO:0032502]; face development [GO:0060324]; fat cell differentiation [GO:0045444]; gene expression [GO:0010467]; hippocampus development [GO:0021766]; intracellular transport [GO:0046907]; leptin-mediated signaling pathway [GO:0033210]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of appetite by leptin-mediated signaling pathway [GO:0038108]; negative regulation of blood pressure [GO:0045776]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of multicellular organism growth [GO:0040018]; protein folding [GO:0006457]; regulation of cilium beat frequency involved in ciliary motility [GO:0060296]; regulation of stress fiber assembly [GO:0051492]; response to leptin [GO:0044321]; sensory perception of smell [GO:0007608]; social behavior [GO:0035176]; spermatid development [GO:0007286]; striatum development [GO:0021756]; vasodilation [GO:0042311] GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0006457; GO:0007286; GO:0007608; GO:0010467; GO:0010629; GO:0014824; GO:0021756; GO:0021766; GO:0021987; GO:0030837; GO:0031514; GO:0032502; GO:0033210; GO:0034260; GO:0035176; GO:0036064; GO:0038108; GO:0040018; GO:0042311; GO:0044321; GO:0045444; GO:0045494; GO:0045776; GO:0046907; GO:0048854; GO:0050910; GO:0051082; GO:0051131; GO:0051216; GO:0051492; GO:0060271; GO:0060296; GO:0060324; GO:0061629; GO:1902636; GO:1905515 18899 XM_044319850.1 0 4 1 13 6 NA NA NA NA NA NA 18900 XM_029358177.2 990 772 663 1289 1294 Q14149 2.36e-176 MORC family CW-type zinc finger protein 3 (Nuclear matrix protein 2) (Zinc finger CW-type coiled-coil domain protein 3) Homo sapiens (Human) innate immune response [GO:0045087]; maintenance of protein location in nucleus [GO:0051457]; negative regulation of fibroblast proliferation [GO:0048147]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cellular senescence [GO:2000774]; post-embryonic development [GO:0009791]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821] GO:0003723; GO:0005634; GO:0005654; GO:0005694; GO:0006468; GO:0008270; GO:0009791; GO:0016363; GO:0016605; GO:0016887; GO:0018105; GO:0035064; GO:0045087; GO:0048147; GO:0050821; GO:0051457; GO:2000774 18901 XR_006397185.1 32 0 4 11 15 NA NA NA NA NA NA 18902 XM_044314368.1 0 0 0 0 6 NA NA NA NA NA NA 18903 XM_044327049.1 458 162 74 263 102 NA NA NA NA NA NA 18904 XM_029337323.2 434 275 166 542 465 NA NA NA NA NA NA 18905 XM_044326011.1 619 602 14 575 201 Q9UGM3 1.24e-58 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 18906 XM_044326011.1 619 602 14 575 201 Q9UGM3 7.24e-58 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 18907 XM_044326011.1 619 602 14 575 201 Q9UGM3 2.31e-57 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 18908 XM_044326011.1 619 602 14 575 201 Q9UGM3 1.17e-56 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 18909 XM_044326011.1 619 602 14 575 201 Q9UGM3 3.68e-56 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 18910 XM_044326011.1 619 602 14 575 201 Q9UGM3 1.13e-55 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 18911 XM_044326011.1 619 602 14 575 201 Q9UGM3 1.54e-55 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 18912 XM_044326011.1 619 602 14 575 201 Q9UGM3 2.96e-55 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 18913 XM_044326011.1 619 602 14 575 201 Q9UGM3 4.58e-53 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 18914 XM_044326011.1 619 602 14 575 201 Q9UGM3 9.63e-53 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 18915 XM_044326011.1 619 602 14 575 201 Q9UGM3 9.85e-31 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 18916 XM_044326011.1 619 602 14 575 201 Q9UGM3 1.12e-22 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 18917 XM_044308330.1 0 0 0 6 186 NA NA NA NA NA NA 18918 XM_044310755.1 4 98 352 241 377 NA NA NA NA NA NA 18919 XM_044322658.1 10 0 9 35 14 P0CT39 1.6e-88 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 18920 XM_044322383.1 27 42 25 25 57 NA NA NA NA NA NA 18921 XR_006396407.1 72 0 0 0 70 NA NA NA NA NA NA 18922 XM_044317265.1 159 137 75 91 143 Q9Z0R0 3.63e-84 Serine/threonine-protein kinase haspin (EC 2.7.11.1) (Germ cell-specific gene 2 protein) (Haploid germ cell-specific nuclear protein kinase) Mus musculus (Mouse) chromatin organization [GO:0006325]; chromosome organization involved in meiotic cell cycle [GO:0070192]; gene expression [GO:0010467]; homologous chromosome segregation [GO:0045143]; intracellular signal transduction [GO:0035556]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; mitotic spindle assembly checkpoint signaling [GO:0007094]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; protein localization to chromosome, centromeric region [GO:0071459]; protein phosphorylation [GO:0006468] GO:0000278; GO:0001673; GO:0003677; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005694; GO:0005737; GO:0005813; GO:0005819; GO:0006325; GO:0006468; GO:0007064; GO:0007094; GO:0010467; GO:0035173; GO:0035556; GO:0045143; GO:0070192; GO:0071459; GO:0072354; GO:0106310; GO:2000134 18923 XR_006392726.1 0 8 2 26 4 NA NA NA NA NA NA 18924 XM_044317511.1 1 13 15 23 0 NA NA NA NA NA NA 18925 XM_029331030.2 1204 1149 828 1379 1009 Q68F70 0 Integrator complex subunit 4 (Int4) Xenopus laevis (African clawed frog) NA GO:0005634 18926 XM_029346082.2 192 35 315 157 237 Q9WTN5 1.47e-57 Two pore calcium channel protein 1 (Voltage-dependent calcium channel protein TPC1) Rattus norvegicus (Rat) endocytosis involved in viral entry into host cell [GO:0075509]; positive regulation of autophagy [GO:0010508]; regulation of ion transmembrane transport [GO:0034765]; sodium ion transmembrane transport [GO:0035725] GO:0005244; GO:0005248; GO:0005765; GO:0010008; GO:0010508; GO:0015280; GO:0016020; GO:0019905; GO:0031901; GO:0034765; GO:0035725; GO:0036019; GO:0042802; GO:0042803; GO:0055038; GO:0072345; GO:0075509; GO:0080025; GO:0097682 18927 XM_044321011.1 0 228 0 69 225 NA NA NA NA NA NA 18928 XM_044321010.1 0 47 260 463 664 NA NA NA NA NA NA 18929 XM_044308989.1 90 43 14 124 76 NA NA NA NA NA NA 18930 XR_006395268.1 8 6 5 16 5 NA NA NA NA NA NA 18931 XR_006394053.1 230 227 311 334 133 NA NA NA NA NA NA 18932 XM_029330045.2 310 108 146 167 103 O67554 2.19e-38 Putative L-lysine 2,3-aminomutase aq_1632 (LAM) (EC 5.4.3.-) Aquifex aeolicus (strain VF5) NA GO:0016853; GO:0046872; GO:0051539 18933 XM_044323712.1 14 1 6 5 53 NA NA NA NA NA NA 18934 XM_029346485.2 353 231 96 328 344 Q0VCH8 7.44e-52 Transmembrane protein 65 Bos taurus (Bovine) cardiac ventricle development [GO:0003231]; regulation of cardiac conduction [GO:1903779] GO:0003231; GO:0005739; GO:0005743; GO:0005886; GO:0014704; GO:1903779 18935 XM_029340927.2 10 6 0 4 55 NA NA NA NA NA NA 18936 XM_044316211.1 0 0 0 15 9 NA NA NA NA NA NA 18937 XR_006393973.1 1365 487 716 1816 2112 NA NA NA NA NA NA 18938 XM_029340942.2 66 29 117 72 221 Q8NDV2 2.51e-38 G-protein coupled receptor 26 Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0005886; GO:0007186; GO:0007189 18939 XM_029339907.2 90 54 94 74 78 Q6NN55 3.1e-105 Lysophospholipid acyltransferase 6 (LPLAT 6) (EC 2.3.1.-) (EC 2.3.1.23) (EC 2.3.1.n6) (EC 2.3.1.n7) (Membrane-bound acyltransferase 6) (MBOA 6) (Oysgedart) (Oys) Drosophila melanogaster (Fruit fly) germ cell migration [GO:0008354]; lipid modification [GO:0030258]; phospholipid metabolic process [GO:0006644]; plasma membrane organization [GO:0007009]; sperm individualization [GO:0007291] GO:0005783; GO:0006644; GO:0007009; GO:0007291; GO:0008354; GO:0016020; GO:0016746; GO:0030258; GO:0071617 18940 XR_006395954.1 607 824 156 466 578 NA NA NA NA NA NA 18941 XM_044321986.1 29 12 42 24 187 NA NA NA NA NA NA 18942 XM_029333715.2 550 275 329 744 402 Q640B4 0 Crossover junction endonuclease MUS81 (EC 3.1.22.-) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) DNA catabolic process, endonucleolytic [GO:0000737]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302] GO:0000737; GO:0003677; GO:0006302; GO:0006310; GO:0008821; GO:0043596; GO:0046872 18943 XM_044323675.1 5 17 10 1 33 NA NA NA NA NA NA 18944 XM_044321757.1 107 94 105 184 114 NA NA NA NA NA NA 18945 XM_044319246.1 708 429 564 544 976 A0JP86 1.56e-132 Laminin subunit gamma-1 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell adhesion [GO:0007155] GO:0005576; GO:0005604; GO:0007155 18946 XM_044319246.1 708 429 564 544 976 A0JP86 5.3e-42 Laminin subunit gamma-1 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell adhesion [GO:0007155] GO:0005576; GO:0005604; GO:0007155 18947 XM_044319246.1 708 429 564 544 976 A0JP86 1.43e-26 Laminin subunit gamma-1 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell adhesion [GO:0007155] GO:0005576; GO:0005604; GO:0007155 18948 XM_044319246.1 708 429 564 544 976 A0JP86 1.19e-23 Laminin subunit gamma-1 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell adhesion [GO:0007155] GO:0005576; GO:0005604; GO:0007155 18949 XM_044319246.1 708 429 564 544 976 A0JP86 1.2e-23 Laminin subunit gamma-1 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell adhesion [GO:0007155] GO:0005576; GO:0005604; GO:0007155 18950 XM_029338868.2 360 513 116 604 230 Q9IA95 5.51e-47 Secreted frizzled-related protein 3 (sFRP-3) (Frizzled-related protein 1) (FrzB-1) Gallus gallus (Chicken) cochlea morphogenesis [GO:0090103]; convergent extension involved in organogenesis [GO:0060029]; epithelial cell development [GO:0002064]; hepatocyte differentiation [GO:0070365]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cartilage development [GO:0061037]; negative regulation of cell development [GO:0010721]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of hepatocyte differentiation [GO:0070367]; negative regulation of Wnt signaling pathway [GO:0030178]; neural crest cell differentiation [GO:0014033]; positive regulation of apoptotic process [GO:0043065]; positive regulation of fat cell differentiation [GO:0045600]; somite development [GO:0061053]; Wnt signaling pathway [GO:0016055] GO:0002064; GO:0005576; GO:0008285; GO:0010721; GO:0014033; GO:0016055; GO:0017147; GO:0030178; GO:0030308; GO:0043065; GO:0045600; GO:0060029; GO:0061037; GO:0061053; GO:0070365; GO:0070367; GO:0090090; GO:0090103 18951 XM_029338713.2 27 0 0 0 0 NA NA NA NA NA NA 18952 XM_029342105.2 4984 3828 2794 4774 4749 Q0P594 0 Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform (PP2A-beta) (EC 3.1.3.16) Bos taurus (Bovine) apoptotic mitochondrial changes [GO:0008637]; mitotic cell cycle [GO:0000278]; negative regulation of gene expression [GO:0010629]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; response to antibiotic [GO:0046677]; response to endoplasmic reticulum stress [GO:0034976]; response to hydrogen peroxide [GO:0042542] GO:0000159; GO:0000278; GO:0000775; GO:0000922; GO:0004722; GO:0005634; GO:0005737; GO:0005829; GO:0008637; GO:0010629; GO:0010804; GO:0017018; GO:0032088; GO:0034976; GO:0042542; GO:0043161; GO:0046677; GO:0046872 18953 XM_044325816.1 427 17 401 70 203 NA NA NA NA NA NA 18954 XM_044311391.1 1 18 6 5 13 NA NA NA NA NA NA 18955 XM_044312448.1 4 4 32 16 12 NA NA NA NA NA NA 18956 XR_006397082.1 8 15 18 10 5 NA NA NA NA NA NA 18957 XM_044328006.1 63 22 10 32 3 NA NA NA NA NA NA 18958 XM_044314800.1 5 0 0 7 48 NA NA NA NA NA NA 18959 XM_044308436.1 0 110 16 122 51 NA NA NA NA NA NA 18960 XM_029330599.2 5 0 7 1 0 NA NA NA NA NA NA 18961 XM_029341522.2 0 0 0 75 0 C3ZQF9 1.58e-25 QRFP-like peptide receptor Branchiostoma floridae (Florida lancelet) (Amphioxus) cellular response to peptide [GO:1901653]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:1901653 18962 XM_029356759.2 752 620 755 813 775 Q8NHP1 1.38e-97 Aflatoxin B1 aldehyde reductase member 4 (EC 1.-.-.-) (AFB1 aldehyde reductase 3) (AFB1-AR 3) (Aldoketoreductase 7-like) Homo sapiens (Human) NA GO:0004033; GO:0005737; GO:0005829; GO:0070062 18963 XM_044329077.1 32 14 51 59 91 NA NA NA NA NA NA 18964 XM_044317220.1 857 562 514 1207 1080 Q9Y3D0 2.03e-68 Cytosolic iron-sulfur assembly component 2B (MSS19-interacting protein of 18 kDa) (Mitotic spindle-associated MMXD complex subunit MIP18) (Protein FAM96B) Homo sapiens (Human) chromosome segregation [GO:0007059]; iron-sulfur cluster assembly [GO:0016226]; protein maturation by [4Fe-4S] cluster transfer [GO:0106035]; protein maturation by iron-sulfur cluster transfer [GO:0097428] GO:0005634; GO:0005654; GO:0005737; GO:0005819; GO:0005829; GO:0007059; GO:0016226; GO:0030496; GO:0071817; GO:0097361; GO:0097428; GO:0106035 18965 XM_029330627.2 5 0 0 4 10 NA NA NA NA NA NA 18966 XM_044323746.1 35 42 61 55 244 NA NA NA NA NA NA 18967 XM_029347596.2 544 317 191 507 559 Q9P055 6.79e-86 JNK1/MAPK8-associated membrane protein (JKAMP) (JNK1-associated membrane protein) (JAMP) (Medulloblastoma antigen MU-MB-50.4) Homo sapiens (Human) response to unfolded protein [GO:0006986]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0005789; GO:0006986; GO:0030433; GO:0031625 18968 XR_006392875.1 41 2 25 5 151 NA NA NA NA NA NA 18969 XM_029356286.2 1861 1640 1030 1808 1392 O94923 1.58e-146 D-glucuronyl C5-epimerase (EC 5.1.3.17) (Heparan sulfate C5-epimerase) (Hsepi) (Heparin/heparan sulfate:glucuronic acid C5-epimerase) (Heparosan-N-sulfate-glucuronate 5-epimerase) Homo sapiens (Human) heparan sulfate proteoglycan biosynthetic process [GO:0015012]; heparin biosynthetic process [GO:0030210] GO:0000139; GO:0005509; GO:0005794; GO:0015012; GO:0016857; GO:0030210; GO:0042803; GO:0047464 18970 XM_029351058.2 166 91 135 158 214 NA NA NA NA NA NA 18971 XM_044312566.1 0 533 127 366 385 NA NA NA NA NA NA 18972 XR_003827208.2 57 42 99 97 127 NA NA NA NA NA NA 18973 XM_044328883.1 0 3 12 0 7 Q09575 5.77e-40 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 18974 XM_044317447.1 0 0 0 0 54 Q15034 2.5e-24 Probable E3 ubiquitin-protein ligase HERC3 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 3) (HECT-type E3 ubiquitin transferase HERC3) Homo sapiens (Human) protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0005737; GO:0005829; GO:0006511; GO:0016567; GO:0031410; GO:0061630 18975 XR_006396585.1 74 0 4 77 61 NA NA NA NA NA NA 18976 XM_044327435.1 0 24 0 24 59 Q9QYP1 0 Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7) Rattus norvegicus (Rat) amyloid-beta clearance by cellular catabolic process [GO:0150094]; anatomical structure development [GO:0048856]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; proximal/distal pattern formation [GO:0009954]; receptor clustering [GO:0043113]; regulation of protein phosphorylation [GO:0001932]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001932; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0008104; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030326; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0043113; GO:0044853; GO:0048699; GO:0048813; GO:0048856; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 18977 XM_044327435.1 0 24 0 24 59 Q9QYP1 0 Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7) Rattus norvegicus (Rat) amyloid-beta clearance by cellular catabolic process [GO:0150094]; anatomical structure development [GO:0048856]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; proximal/distal pattern formation [GO:0009954]; receptor clustering [GO:0043113]; regulation of protein phosphorylation [GO:0001932]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001932; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0008104; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030326; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0043113; GO:0044853; GO:0048699; GO:0048813; GO:0048856; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 18978 XM_044327435.1 0 24 0 24 59 Q9QYP1 5.27e-137 Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7) Rattus norvegicus (Rat) amyloid-beta clearance by cellular catabolic process [GO:0150094]; anatomical structure development [GO:0048856]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; proximal/distal pattern formation [GO:0009954]; receptor clustering [GO:0043113]; regulation of protein phosphorylation [GO:0001932]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001932; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0008104; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030326; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0043113; GO:0044853; GO:0048699; GO:0048813; GO:0048856; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 18979 XM_029332872.2 5662 6166 4812 10299 8215 B8VIX3 0 Uncharacterized skeletal organic matrix protein 6 (Uncharacterized SOMP-6) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 18980 XM_029346476.2 11 2 5 16 5 NA NA NA NA NA NA 18981 XM_029356740.2 882 697 588 824 931 NA NA NA NA NA NA 18982 XM_044327952.1 6 8 36 14 96 NA NA NA NA NA NA 18983 XM_029334907.2 76 470 0 559 404 E2QWQ2 0 Serine/threonine-protein kinase NLK (EC 2.7.11.24) (Nemo-like kinase) Canis lupus familiaris (Dog) (Canis familiaris) intracellular signal transduction [GO:0035556]; negative regulation of Wnt signaling pathway [GO:0030178]; peptidyl-threonine phosphorylation [GO:0018107]; protein autophosphorylation [GO:0046777]; protein stabilization [GO:0050821]; regulation of DNA-templated transcription [GO:0006355]; serine phosphorylation of STAT protein [GO:0042501]; transforming growth factor beta receptor signaling pathway [GO:0007179]; Wnt signaling pathway [GO:0016055] GO:0000287; GO:0004674; GO:0004707; GO:0005524; GO:0005634; GO:0005737; GO:0006355; GO:0007179; GO:0016055; GO:0018107; GO:0030178; GO:0031625; GO:0035556; GO:0042169; GO:0042501; GO:0046777; GO:0050821; GO:0106310; GO:0140297 18984 XM_044328926.1 6805 9351 4908 20400 11382 B3EWY6 9.08e-24 Skeletal aspartic acid-rich protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 18985 XR_003827934.2 1 3 0 8 0 NA NA NA NA NA NA 18986 XM_044325723.1 1 59 7 12 30 P0CT40 4.48e-70 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 18987 XM_044310052.1 15 14 0 0 3 NA NA NA NA NA NA 18988 XM_044312456.1 14 75 3 10 26 NA NA NA NA NA NA 18989 XM_044329215.1 83 35 13 37 4 NA NA NA NA NA NA 18990 XM_029327379.2 273 101 86 122 76 Q6GNV7 3.58e-59 Solute carrier family 49 member 4 homolog (Disrupted in renal carcinoma protein 2 homolog) Xenopus laevis (African clawed frog) NA GO:0005765; GO:0022857 18991 XM_044317101.1 16 21 2 57 18 NA NA NA NA NA NA 18992 XM_029333498.2 33 50 11 0 33 Q1PSW8 8.53e-24 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (mLin41) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Mus musculus (Mouse) 3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to organic substance [GO:0071310]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA processing [GO:0035196]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; post-transcriptional regulation of gene expression [GO:0010608]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein metabolic process [GO:0051246]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0001843; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0010608; GO:0017148; GO:0021915; GO:0030371; GO:0035196; GO:0035198; GO:0035278; GO:0043161; GO:0051246; GO:0051865; GO:0060964; GO:0061158; GO:0061630; GO:0071310; GO:0072089; GO:2000177; GO:2000637 18993 XM_029324549.2 40 19 54 39 25 NA NA NA NA NA NA 18994 XM_029345444.2 0 3 17 6 5 P55112 1.55e-40 Zinc metalloproteinase nas-4 (EC 3.4.24.-) (Nematode astacin 4) Caenorhabditis elegans proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0006508; GO:0008270 18995 XR_003825072.2 456 136 18 305 327 NA NA NA NA NA NA 18996 XM_044308053.1 378 277 129 356 153 NA NA NA NA NA NA 18997 XM_029356980.2 0 44 38 61 25 Q6QNK2 1.24e-71 Adhesion G-protein coupled receptor D1 (G-protein coupled receptor 133) (G-protein coupled receptor PGR25) Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0005654; GO:0005886; GO:0007166; GO:0007186; GO:0007189; GO:0016020 18998 XM_044313354.1 3 1 0 0 39 Q9PTU6 8.96e-21 Uridylate-specific endoribonuclease (EC 4.6.1.-) (Pancreatic protein with two somatomedin-B domains) (Protein endoU) Paralichthys olivaceus (Bastard halibut) (Hippoglossus olivaceus) immune response [GO:0006955] GO:0003723; GO:0004521; GO:0005044; GO:0005576; GO:0006955; GO:0016829; GO:0030247; GO:0046872 18999 XM_029344674.2 682 591 449 1018 724 P21868 0 Casein kinase II subunit alpha (CK II) (EC 2.7.11.1) Gallus gallus (Chicken) peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; regulation of cell cycle [GO:0051726]; rhythmic process [GO:0048511]; Wnt signaling pathway [GO:0016055] GO:0004674; GO:0005524; GO:0005634; GO:0005829; GO:0005956; GO:0016055; GO:0018105; GO:0018107; GO:0048511; GO:0051726; GO:0106310 19000 XM_044323730.1 0 20 0 0 7 NA NA NA NA NA NA 19001 XM_029357608.2 47 19 20 25 70 Q5BB35 3.8e-65 Pre-mRNA-splicing factor cwc2 Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) cell cycle [GO:0007049]; mRNA cis splicing, via spliceosome [GO:0045292]; positive regulation of cell cycle [GO:0045787]; positive regulation of RNA splicing [GO:0033120]; spliceosomal snRNP assembly [GO:0000387] GO:0000387; GO:0000974; GO:0007049; GO:0017070; GO:0033120; GO:0036002; GO:0045292; GO:0045787; GO:0046872; GO:0071006; GO:0071007; GO:0071014 19002 XM_044321919.1 55 0 0 0 0 Q8IRC7 7.42e-77 LIM/homeobox protein Awh (Protein arrowhead) Drosophila melanogaster (Fruit fly) compound eye development [GO:0048749]; imaginal disc development [GO:0007444]; neuron differentiation [GO:0030182]; regulation of DNA-templated transcription [GO:0006355]; regulation of gene expression [GO:0010468]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000977; GO:0000981; GO:0003700; GO:0005634; GO:0006355; GO:0006357; GO:0007444; GO:0010468; GO:0030182; GO:0046872; GO:0048749 19003 XM_029337620.2 0 0 7 0 37 P97390 0 Vacuolar protein sorting-associated protein 45 (mVps45) Mus musculus (Mouse) intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0005794; GO:0006886; GO:0008021; GO:0010008; GO:0016020; GO:0016192 19004 XM_044306944.1 63 0 0 25 70 NA NA NA NA NA NA 19005 XM_029332927.2 7002 7830 3345 6862 5873 Q5R651 7.93e-83 14-3-3 protein zeta/delta Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) protein phosphorylation [GO:0006468]; regulation of ERK1 and ERK2 cascade [GO:0070372]; signal transduction [GO:0007165] GO:0006468; GO:0007165; GO:0042470; GO:0042802; GO:0050815; GO:0070372; GO:0140311 19006 XM_044313282.1 161 190 48 233 112 NA NA NA NA NA NA 19007 XM_029330257.2 189 137 106 158 212 A0A1L8EYB2 4.57e-127 Dynein axonemal assembly factor 8 (Dynein axonemal-associated protein 1) Xenopus laevis (African clawed frog) outer dynein arm assembly [GO:0036158] GO:0036158; GO:0070840; GO:0120293 19008 XR_006392878.1 41 2 25 5 151 NA NA NA NA NA NA 19009 XM_044323126.1 133 9 12 103 8 NA NA NA NA NA NA 19010 XM_029332102.2 31 0 0 50 0 NA NA NA NA NA NA 19011 XM_044323686.1 13 13 48 3 14 NA NA NA NA NA NA 19012 XM_044313747.1 26 1 10 4 101 NA NA NA NA NA NA 19013 XM_029339998.2 4984 4399 2590 3018 3919 P05630 2.86e-37 ATP synthase subunit delta, mitochondrial (ATP synthase F1 subunit delta) (F-ATPase delta subunit) Bos taurus (Bovine) aerobic respiration [GO:0009060]; mitochondrial proton-transporting ATP synthase complex assembly [GO:0033615]; proton motive force-driven ATP synthesis [GO:0015986]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776]; proton transmembrane transport [GO:1902600] GO:0000275; GO:0005740; GO:0005753; GO:0009060; GO:0015078; GO:0015986; GO:0033615; GO:0042776; GO:0045259; GO:0046933; GO:1902600 19014 XM_029344530.2 236 51 124 96 145 Q5RC69 2.14e-86 Deoxycytidylate deaminase (EC 3.5.4.12) (dCMP deaminase) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) nucleotide biosynthetic process [GO:0009165]; pyrimidine nucleotide metabolic process [GO:0006220] GO:0004132; GO:0006220; GO:0008270; GO:0009165 19015 XM_029357583.2 0 86 88 0 71 Q8BTK5 6.66e-54 SET and MYND domain-containing protein 4 (EC 2.1.1.-) Mus musculus (Mouse) heart development [GO:0007507]; methylation [GO:0032259] GO:0005634; GO:0005737; GO:0007507; GO:0008168; GO:0032259; GO:0042826; GO:0046872 19016 XM_029326540.2 0 5 17 20 32 NA NA NA NA NA NA 19017 XM_044321889.1 6168 4633 4013 5544 5638 Q6GN42 1.68e-177 Choline transporter-like protein 4 (Solute carrier family 44 member 4) Xenopus laevis (African clawed frog) acetylcholine biosynthetic process [GO:0008292]; acetylcholine secretion [GO:0061526]; choline transport [GO:0015871]; neuromast hair cell development [GO:0035675]; otolith formation [GO:0032475]; positive regulation of cell growth [GO:0030307] GO:0008292; GO:0015220; GO:0015871; GO:0016324; GO:0030307; GO:0032475; GO:0035675; GO:0061526 19018 XM_029342212.2 1554 1172 492 1357 1099 Q5RDE9 8.14e-39 Leptin receptor overlapping transcript-like 1 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0016020 19019 XM_029341210.2 75 87 30 449 173 A8WGF4 0 Intraflagellar transport protein 122 homolog Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cilium assembly [GO:0060271]; intraciliary retrograde transport [GO:0035721]; intraciliary transport [GO:0042073]; negative regulation of smoothened signaling pathway [GO:0045879]; protein localization to cilium [GO:0061512] GO:0005737; GO:0005929; GO:0030991; GO:0035721; GO:0036064; GO:0042073; GO:0045879; GO:0060271; GO:0061512 19020 XM_029327768.2 0 0 9 0 1 NA NA NA NA NA NA 19021 XM_029339396.2 1111 675 307 137 333 Q3SYR7 2.25e-79 60S ribosomal protein L9 Bos taurus (Bovine) cytoplasmic translation [GO:0002181] GO:0002181; GO:0003735; GO:0019843; GO:0022625 19022 XM_029327251.2 291 260 192 327 297 NA NA NA NA NA NA 19023 XM_029329246.2 75 19 107 27 427 NA NA NA NA NA NA 19024 XM_029338656.2 6 3 2 7 9 NA NA NA NA NA NA 19025 XM_044328273.1 77 29 17 28 36 NA NA NA NA NA NA 19026 XM_029350683.2 1519 1722 1325 1634 1643 Q5SS90 5.08e-22 Uncharacterized protein C7orf57 homolog Mus musculus (Mouse) NA NA 19027 XM_029328137.2 12 0 0 15 0 NA NA NA NA NA NA 19028 XM_029331709.2 2172 3648 200 3142 430 Q8BZ20 9.61e-60 Protein mono-ADP-ribosyltransferase PARP12 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 12) (ARTD12) (Poly [ADP-ribose] polymerase 12) (PARP-12) (Zinc finger CCCH domain-containing protein 1) Mus musculus (Mouse) protein auto-ADP-ribosylation [GO:0070213] GO:0003950; GO:0005634; GO:0016779; GO:0046872; GO:0070213; GO:0140803; GO:1990404 19029 XM_029350488.2 61 6 0 45 44 Q14CH1 0 Molybdenum cofactor sulfurase (MCS) (MOS) (MoCo sulfurase) (EC 2.8.1.9) (Molybdenum cofactor sulfurtransferase) Mus musculus (Mouse) Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdopterin cofactor metabolic process [GO:0043545] GO:0006777; GO:0008265; GO:0016829; GO:0030151; GO:0030170; GO:0043545; GO:0102867 19030 XM_044318485.1 11 3 10 0 10 NA NA NA NA NA NA 19031 XR_006398188.1 6 0 0 0 0 NA NA NA NA NA NA 19032 XR_006392314.1 18 16 21 9 49 NA NA NA NA NA NA 19033 XM_044323283.1 239 174 150 161 104 Q29RU2 6.38e-38 Oncoprotein-induced transcript 3 protein Bos taurus (Bovine) NA GO:0005509; GO:0005635 19034 XM_044310607.1 246 233 241 217 200 Q5F364 0 Multidrug resistance-associated protein 1 (EC 7.6.2.2) (ATP-binding cassette sub-family C member 1) (Glutathione-S-conjugate-translocating ATPase ABCC1) (EC 7.6.2.3) (Leukotriene C(4) transporter) (LTC4 transporter) Gallus gallus (Chicken) glutathione transmembrane transport [GO:0034775]; lipid transport [GO:0006869]; transmembrane transport [GO:0055085]; xenobiotic transport [GO:0042908] GO:0005524; GO:0006869; GO:0008559; GO:0016020; GO:0016323; GO:0016887; GO:0034634; GO:0034775; GO:0042626; GO:0042908; GO:0055085 19035 XM_044307804.1 9 1 57 25 48 NA NA NA NA NA NA 19036 XM_044308074.1 285 320 307 455 226 Q8IV61 1.1e-100 Ras guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1) Homo sapiens (Human) MAPK cascade [GO:0000165]; positive regulation of GTPase activity [GO:0043547]; Ras protein signal transduction [GO:0007265]; small GTPase mediated signal transduction [GO:0007264] GO:0000165; GO:0005085; GO:0005096; GO:0005509; GO:0005886; GO:0007264; GO:0007265; GO:0019900; GO:0019992; GO:0031267; GO:0032045; GO:0043547; GO:0048471 19037 XR_006397189.1 3 0 0 7 0 NA NA NA NA NA NA 19038 XR_006397479.1 0 6 2 7 7 NA NA NA NA NA NA 19039 XM_029353488.2 276 57 79 90 168 Q49A88 6.92e-27 Coiled-coil domain-containing protein 14 Homo sapiens (Human) protein localization to centrosome [GO:0071539]; substantia nigra development [GO:0021762] GO:0005737; GO:0005813; GO:0021762; GO:0034451; GO:0071539 19040 XR_006397491.1 0 9 0 0 0 NA NA NA NA NA NA 19041 XM_044320025.1 0 110 1 0 38 NA NA NA NA NA NA 19042 XM_044320776.1 0 6 30 9 21 B3EWZ5 1.78e-24 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 19043 XM_044320776.1 0 6 30 9 21 B3EWZ5 1.39e-22 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 19044 XM_044320776.1 0 6 30 9 21 B3EWZ5 4.49e-22 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 19045 XM_044320776.1 0 6 30 9 21 B3EWZ5 8.8e-22 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 19046 XM_044320776.1 0 6 30 9 21 B3EWZ5 1.2e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 19047 XM_044320776.1 0 6 30 9 21 B3EWZ5 5.31e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 19048 XM_044320776.1 0 6 30 9 21 B3EWZ5 5.47e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 19049 XM_044320776.1 0 6 30 9 21 B3EWZ5 8.76e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 19050 XM_029329249.2 275 160 238 375 505 NA NA NA NA NA NA 19051 XM_029331192.2 41 5 129 149 0 NA NA NA NA NA NA 19052 XM_029332076.2 4031 3314 1812 2616 2138 O43765 4.78e-57 Small glutamine-rich tetratricopeptide repeat-containing protein alpha (Alpha-SGT) (Vpu-binding protein) (UBP) Homo sapiens (Human) negative regulation of ER-associated ubiquitin-dependent protein catabolic process [GO:1903070]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059]; positive regulation of ER-associated ubiquitin-dependent protein catabolic process [GO:1903071]; post-translational protein targeting to endoplasmic reticulum membrane [GO:0006620]; tail-anchored membrane protein insertion into ER membrane [GO:0071816]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0005634; GO:0005737; GO:0005829; GO:0006620; GO:0016020; GO:0030433; GO:0042802; GO:0043621; GO:0060090; GO:0071816; GO:0072380; GO:1903070; GO:1903071; GO:1904288; GO:2000059 19053 XM_044324556.1 260 539 114 217 197 NA NA NA NA NA NA 19054 XM_029338103.2 178 73 75 64 66 NA NA NA NA NA NA 19055 XM_044325663.1 9 4 46 16 6 NA NA NA NA NA NA 19056 XM_029323985.2 190 262 589 224 407 Q9MYM7 1.88e-25 Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.86) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1) Pongo pygmaeus (Bornean orangutan) lipid metabolic process [GO:0006629]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0006629; GO:0047275 19057 XM_044326680.1 219 718 428 242 139 Q8QZR1 4e-165 Tyrosine aminotransferase (TAT) (EC 2.6.1.5) (L-tyrosine:2-oxoglutarate aminotransferase) Mus musculus (Mouse) 2-oxoglutarate metabolic process [GO:0006103]; amino acid metabolic process [GO:0006520]; biosynthetic process [GO:0009058]; glutamate metabolic process [GO:0006536]; L-phenylalanine catabolic process [GO:0006559]; response to dexamethasone [GO:0071548]; response to glucocorticoid [GO:0051384]; response to mercury ion [GO:0046689]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; tyrosine catabolic process [GO:0006572] GO:0004838; GO:0005739; GO:0006103; GO:0006520; GO:0006536; GO:0006559; GO:0006572; GO:0006979; GO:0009058; GO:0014070; GO:0016597; GO:0030170; GO:0042802; GO:0046689; GO:0051384; GO:0071548 19058 XM_029345562.2 2009 2519 2019 3253 2366 Q6GQX6 1.49e-85 Ankyrin repeat and SAM domain-containing protein 6 (SamCystin) (Sterile alpha motif domain-containing protein 6) (SAM domain-containing protein 6) Mus musculus (Mouse) determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822] GO:0001701; GO:0001822; GO:0005737; GO:0007368; GO:0007507; GO:0042802; GO:0097543 19059 XR_006391268.1 520 555 217 389 277 NA NA NA NA NA NA 19060 XM_044307210.1 3479 2788 2546 2749 1928 Q90891 2.42e-172 Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase 2) (MAPKK 2) (EC 2.7.12.2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK2) Gallus gallus (Chicken) NA GO:0004674; GO:0004708; GO:0004713; GO:0005524; GO:0106310 19061 XM_044321098.1 110 152 88 156 119 P02594 2.01e-62 Calmodulin (CaM) Electrophorus electricus (Electric eel) (Gymnotus electricus) NA GO:0005509 19062 XM_044313312.1 0 0 0 12 0 NA NA NA NA NA NA 19063 XM_029340496.2 155 0 75 41 199 Q14123 4.85e-119 Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Cam-PDE 1C) (EC 3.1.4.17) (Hcam3) Homo sapiens (Human) signal transduction [GO:0007165] GO:0004114; GO:0004115; GO:0004117; GO:0005516; GO:0005764; GO:0005829; GO:0007165; GO:0043025; GO:0046872; GO:0047555; GO:0048101 19064 XM_044312627.1 0 3 4 30 0 NA NA NA NA NA NA 19065 XM_029345433.2 239 1134 193 503 569 F6QEU4 1.25e-58 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 19066 XM_029350055.2 13864 11059 5111 9211 5600 P08991 3.05e-65 Histone H2A.V (H2A.F/Z) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 19067 XM_044318304.1 866 590 507 815 672 Q91VA6 4.3e-116 Polymerase delta-interacting protein 2 Mus musculus (Mouse) error-free translesion synthesis [GO:0070987]; mitochondrion morphogenesis [GO:0070584]; mitotic spindle assembly [GO:0090307]; negative regulation of macroautophagy [GO:0016242]; positive regulation of actin filament binding [GO:1904531]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of mitotic cytokinesis [GO:1903490]; positive regulation of Rho guanyl-nucleotide exchange factor activity [GO:2001108]; vascular associated smooth muscle cell proliferation [GO:1990874] GO:0003677; GO:0005634; GO:0005737; GO:0005739; GO:0005759; GO:0005886; GO:0005911; GO:0016242; GO:0030496; GO:0030674; GO:0042645; GO:0045931; GO:0051894; GO:0070584; GO:0070987; GO:0072686; GO:0090307; GO:1903490; GO:1904531; GO:1990874; GO:2001108 19068 XM_044325344.1 12 6 4 0 19 P48733 2.25e-25 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Bos taurus (Bovine) antibacterial innate immune response [GO:0140367]; defense response to Gram-negative bacterium [GO:0050829] GO:0000922; GO:0005201; GO:0005509; GO:0005576; GO:0005929; GO:0016020; GO:0016323; GO:0016324; GO:0031012; GO:0050829; GO:0060170; GO:0140367 19069 XM_044317992.1 2287 9873 2618 5182 16041 NA NA NA NA NA NA 19070 XM_044318728.1 1746 1818 936 1562 1845 Q3SYS4 1.08e-97 Dynein axonemal assembly factor 1 (Leucine-rich repeat-containing protein 50) Bos taurus (Bovine) cilium assembly [GO:0060271] GO:0005930; GO:0060271; GO:0070840 19071 XR_006394530.1 0 0 6 0 1 NA NA NA NA NA NA 19072 XM_044313024.1 50 9 32 57 67 O55164 1.4e-27 Multiple PDZ domain protein (Multi-PDZ domain protein 1) Rattus norvegicus (Rat) cell adhesion [GO:0007155]; dendrite development [GO:0016358]; intracellular protein transport [GO:0006886]; intracellular signal transduction [GO:0035556]; myelination [GO:0042552] GO:0005737; GO:0005923; GO:0006886; GO:0007155; GO:0008022; GO:0012505; GO:0014069; GO:0016324; GO:0016327; GO:0016358; GO:0030425; GO:0031410; GO:0035003; GO:0035556; GO:0042552; GO:0043220; GO:0045202; GO:0098978 19073 XM_044326598.1 5 57 0 39 0 Q91ZV7 4.57e-51 Plexin domain-containing protein 1 (Tumor endothelial marker 7) Mus musculus (Mouse) spinal cord development [GO:0021510] GO:0005737; GO:0005886; GO:0005923; GO:0021510; GO:0030425; GO:0043025; GO:0043235 19074 XM_029338559.2 1745 1361 833 1313 1230 Q5R787 3.79e-97 ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) protein secretion [GO:0009306]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0005096; GO:0005829; GO:0009306; GO:0016192; GO:0046872 19075 XM_029332621.2 69 0 92 213 298 NA NA NA NA NA NA 19076 XM_044320888.1 734 373 456 583 752 Q8IV35 4.05e-95 WD repeat-containing protein 49 Homo sapiens (Human) NA NA 19077 XM_044313372.1 34 1 14 20 24 Q21565 8.02e-88 Putative ammonium transporter 3 Caenorhabditis elegans ammonium homeostasis [GO:0097272]; ammonium transmembrane transport [GO:0072488] GO:0005886; GO:0008519; GO:0072488; GO:0097272 19078 XM_029338991.2 7 10 21 42 28 NA NA NA NA NA NA 19079 XM_044320723.1 50 17 26 15 0 NA NA NA NA NA NA 19080 XM_044311803.1 181 1006 129 215 1000 NA NA NA NA NA NA 19081 XM_044316812.1 26 0 0 10 17 Q6ZNA5 2.07e-27 Ferric-chelate reductase 1 (EC 1.-.-.-) (Stromal cell-derived receptor 2) (SDR-2) Homo sapiens (Human) cellular iron ion homeostasis [GO:0006879] GO:0006879; GO:0016020; GO:0016722; GO:0046872 19082 XM_029340709.2 134 0 0 0 220 Q9NQX0 8.32e-91 Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.361) (PR domain zinc finger protein 6) (PR domain-containing protein 6) Homo sapiens (Human) chromatin organization [GO:0006325]; histone methylation [GO:0016571]; negative regulation of smooth muscle cell differentiation [GO:0051151]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of gene expression [GO:0010468] GO:0000122; GO:0005634; GO:0006325; GO:0010468; GO:0016571; GO:0022008; GO:0042802; GO:0046872; GO:0051151; GO:0140944 19083 XM_044321864.1 63 64 11 24 11 Q95LU3 2.85e-61 Fibrinogen C domain-containing protein 1 Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0008061; GO:0016020; GO:0046872 19084 XM_029323626.2 282 169 207 329 252 Q504Y2 4.64e-75 Extracellular tyrosine-protein kinase PKDCC (EC 2.7.10.2) (Protein kinase domain-containing protein, cytoplasmic) (Protein kinase-like protein SgK493) (Sugen kinase 493) (Vertebrate lonesome kinase) Homo sapiens (Human) bone mineralization [GO:0030282]; cell differentiation [GO:0030154]; embryonic digestive tract development [GO:0048566]; limb morphogenesis [GO:0035108]; lung alveolus development [GO:0048286]; multicellular organism growth [GO:0035264]; negative regulation of Golgi to plasma membrane protein transport [GO:0042997]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of bone mineralization [GO:0030501]; positive regulation of chondrocyte differentiation [GO:0032332]; protein transport [GO:0015031]; roof of mouth development [GO:0060021]; skeletal system development [GO:0001501] GO:0001501; GO:0004672; GO:0004715; GO:0005524; GO:0005576; GO:0005794; GO:0015031; GO:0018108; GO:0030154; GO:0030282; GO:0030501; GO:0032332; GO:0035108; GO:0035264; GO:0042997; GO:0048286; GO:0048566; GO:0060021 19085 XM_029346362.2 245 400 169 320 406 Q9W6H5 4.66e-59 SUMO-conjugating enzyme UBC9-A (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9-A) (SUMO-protein ligase A) (Ubiquitin carrier protein 9-A) (Ubiquitin carrier protein I-A) (Ubiquitin-conjugating enzyme E2 I-A) (Ubiquitin-protein ligase I-A) Danio rerio (Zebrafish) (Brachydanio rerio) cell division [GO:0051301]; chromosome segregation [GO:0007059]; definitive hemopoiesis [GO:0060216]; embryonic heart tube elongation [GO:0036306]; heart looping [GO:0001947]; hematopoietic stem cell homeostasis [GO:0061484]; protein sumoylation [GO:0016925]; regeneration [GO:0031099]; regulation of mitotic nuclear division [GO:0007088] GO:0001947; GO:0005524; GO:0005634; GO:0007059; GO:0007088; GO:0016925; GO:0019789; GO:0031099; GO:0036306; GO:0051301; GO:0060216; GO:0061484; GO:0061656 19086 XM_029341566.2 0 0 103 157 0 Q9P107 5.77e-98 GEM-interacting protein (GMIP) Homo sapiens (Human) activation of GTPase activity [GO:0090630]; intracellular signal transduction [GO:0035556]; negative regulation of GTPase activity [GO:0034260]; regulation of small GTPase mediated signal transduction [GO:0051056] GO:0005096; GO:0005654; GO:0005829; GO:0005886; GO:0034260; GO:0035556; GO:0046872; GO:0051056; GO:0090630 19087 XM_044310358.1 0 0 7 2 15 NA NA NA NA NA NA 19088 XR_006394896.1 72 37 16 33 148 NA NA NA NA NA NA 19089 XM_029338633.2 416 109 46 85 77 Q5R4J5 1e-44 Synaptotagmin-1 (Synaptotagmin I) (SytI) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cell differentiation [GO:0030154]; positive regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903235] GO:0030154; GO:0030672; GO:0042584; GO:0046872; GO:1903235 19090 XM_029337698.2 127 103 0 229 0 Q9UA35 5.8e-147 Solute carrier family 28 member 3 (Concentrative Na(+)-nucleoside cotransporter 3) (hfCNT) Eptatretus stoutii (Pacific hagfish) NA GO:0005337; GO:0005886; GO:0015293 19091 XR_003827634.2 2 7 2 9 4 NA NA NA NA NA NA 19092 XM_029350247.2 340 226 390 453 257 NA NA NA NA NA NA 19093 XM_044313524.1 95 89 69 123 76 Q8R1A4 4.08e-167 Dedicator of cytokinesis protein 7 (Protein moonlight) Mus musculus (Mouse) activation of GTPase activity [GO:0090630]; axonogenesis [GO:0007409]; establishment of neuroblast polarity [GO:0045200]; hematopoietic progenitor cell differentiation [GO:0002244]; interkinetic nuclear migration [GO:0022027]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of cold-induced thermogenesis [GO:0120163]; neuron projection development [GO:0031175]; pigmentation [GO:0043473]; positive regulation of GTPase activity [GO:0043547]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; postsynaptic specialization assembly [GO:0098698]; regulation of neurogenesis [GO:0050767]; small GTPase mediated signal transduction [GO:0007264] GO:0000226; GO:0002244; GO:0005085; GO:0007264; GO:0007409; GO:0008180; GO:0022027; GO:0030424; GO:0031175; GO:0031267; GO:0031594; GO:0033138; GO:0043473; GO:0043547; GO:0045200; GO:0050767; GO:0090630; GO:0098698; GO:0120163; GO:1904754 19094 XM_044313524.1 95 89 69 123 76 Q8R1A4 8.13e-99 Dedicator of cytokinesis protein 7 (Protein moonlight) Mus musculus (Mouse) activation of GTPase activity [GO:0090630]; axonogenesis [GO:0007409]; establishment of neuroblast polarity [GO:0045200]; hematopoietic progenitor cell differentiation [GO:0002244]; interkinetic nuclear migration [GO:0022027]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of cold-induced thermogenesis [GO:0120163]; neuron projection development [GO:0031175]; pigmentation [GO:0043473]; positive regulation of GTPase activity [GO:0043547]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; postsynaptic specialization assembly [GO:0098698]; regulation of neurogenesis [GO:0050767]; small GTPase mediated signal transduction [GO:0007264] GO:0000226; GO:0002244; GO:0005085; GO:0007264; GO:0007409; GO:0008180; GO:0022027; GO:0030424; GO:0031175; GO:0031267; GO:0031594; GO:0033138; GO:0043473; GO:0043547; GO:0045200; GO:0050767; GO:0090630; GO:0098698; GO:0120163; GO:1904754 19095 XM_044311852.1 0 0 0 116 73 Q8T6A5 0 Tubulin alpha-1 chain (EC 3.6.5.-) Aplysia californica (California sea hare) microtubule-based process [GO:0007017] GO:0005200; GO:0005525; GO:0005737; GO:0005874; GO:0007017; GO:0016787; GO:0046872 19096 XM_044318629.1 645 517 358 685 617 Q6TH47 2.9e-95 STAM-binding protein-like A (EC 3.4.19.-) Danio rerio (Zebrafish) (Brachydanio rerio) protein K63-linked deubiquitination [GO:0070536] GO:0005768; GO:0016020; GO:0032154; GO:0046872; GO:0061578; GO:0070536; GO:0140492 19097 XM_044323040.1 11400 5510 5626 20866 19841 B8V7R6 2.75e-67 Collagen alpha chain Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005201; GO:0005576; GO:0005581 19098 XM_044316749.1 11 0 1 20 8 NA NA NA NA NA NA 19099 XM_044317533.1 0 7 12 0 19 NA NA NA NA NA NA 19100 XM_044311344.1 659 381 393 495 338 B0S5N4 4.23e-89 Plexin A3 Danio rerio (Zebrafish) (Brachydanio rerio) axon extension [GO:0048675]; branching morphogenesis of a nerve [GO:0048755]; embryonic skeletal joint morphogenesis [GO:0060272]; motor neuron axon guidance [GO:0008045]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of collateral sprouting in absence of injury [GO:0048696]; regulation of GTPase activity [GO:0043087]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287] GO:0002116; GO:0005886; GO:0007162; GO:0008045; GO:0008360; GO:0016020; GO:0017154; GO:0030334; GO:0042802; GO:0043087; GO:0048675; GO:0048696; GO:0048755; GO:0050772; GO:0060272; GO:1902287 19101 XM_044325796.1 0 3 2 10 19 Q09575 3.65e-37 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 19102 XM_029326641.2 0 0 3 9 13 NA NA NA NA NA NA 19103 XM_044326279.1 10 0 2 0 6 NA NA NA NA NA NA 19104 XM_044313494.1 12 17 14 49 42 P07911 1.03e-45 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Homo sapiens (Human) antibacterial innate immune response [GO:0140367]; apoptotic signaling pathway [GO:0097190]; autophagy [GO:0006914]; cellular calcium ion homeostasis [GO:0006874]; cellular chloride ion homeostasis [GO:0030644]; cellular defense response [GO:0006968]; cellular phosphate ion homeostasis [GO:0030643]; cellular response to unfolded protein [GO:0034620]; cellular sodium ion homeostasis [GO:0006883]; chaperone-mediated protein folding [GO:0061077]; citric acid secretion [GO:0046720]; collecting duct development [GO:0072044]; connective tissue replacement [GO:0097709]; creatinine homeostasis [GO:0097273]; defense response to Gram-negative bacterium [GO:0050829]; endoplasmic reticulum organization [GO:0007029]; glomerular filtration [GO:0003094]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; juxtaglomerular apparatus development [GO:0072051]; leukocyte cell-cell adhesion [GO:0007159]; lipid metabolic process [GO:0006629]; metanephric ascending thin limb development [GO:0072218]; metanephric distal convoluted tubule development [GO:0072221]; metanephric thick ascending limb development [GO:0072233]; micturition [GO:0060073]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell population proliferation [GO:0008285]; neutrophil migration [GO:1990266]; organ or tissue specific immune response [GO:0002251]; peptidyl-threonine phosphorylation [GO:0018107]; potassium ion homeostasis [GO:0055075]; protein localization to vacuole [GO:0072665]; protein transport into plasma membrane raft [GO:0044861]; regulation of blood pressure [GO:0008217]; regulation of protein transport [GO:0051223]; regulation of urine volume [GO:0035809]; renal sodium ion absorption [GO:0070294]; renal urate salt excretion [GO:0097744]; renal water homeostasis [GO:0003091]; response to lipopolysaccharide [GO:0032496]; response to water deprivation [GO:0009414]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; ubiquitin-dependent ERAD pathway [GO:0030433]; urate transport [GO:0015747]; urea transmembrane transport [GO:0071918] GO:0000922; GO:0002251; GO:0003091; GO:0003094; GO:0005201; GO:0005509; GO:0005615; GO:0005783; GO:0005796; GO:0005929; GO:0006629; GO:0006874; GO:0006883; GO:0006914; GO:0006954; GO:0006968; GO:0007029; GO:0007157; GO:0007159; GO:0008217; GO:0008285; GO:0008380; GO:0009410; GO:0009414; GO:0009986; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0018107; GO:0019864; GO:0019898; GO:0030433; GO:0030643; GO:0030644; GO:0032496; GO:0033209; GO:0033555; GO:0034620; GO:0035809; GO:0044861; GO:0046720; GO:0050829; GO:0051223; GO:0055075; GO:0060073; GO:0060170; GO:0061077; GO:0070062; GO:0070294; GO:0071918; GO:0072044; GO:0072051; GO:0072218; GO:0072221; GO:0072233; GO:0072665; GO:0097190; GO:0097273; GO:0097709; GO:0097744; GO:0140367; GO:1990266 19105 XM_029334956.2 0 6 0 6 1 NA NA NA NA NA NA 19106 XM_029358669.2 12149 16892 4716 13518 8407 NA NA NA NA NA NA 19107 XM_044327739.1 469 277 224 229 182 NA NA NA NA NA NA 19108 XM_044325882.1 861 653 367 951 491 P29341 0 Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1) Mus musculus (Mouse) CRD-mediated mRNA stabilization [GO:0070934]; mRNA processing [GO:0006397]; negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900152]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cytoplasmic translation [GO:2000767]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; RNA splicing [GO:0008380]; RNA-mediated gene silencing [GO:0031047] GO:0000184; GO:0003723; GO:0003729; GO:0003730; GO:0005634; GO:0005737; GO:0005829; GO:0006397; GO:0008022; GO:0008143; GO:0008266; GO:0008380; GO:0010494; GO:0030027; GO:0030425; GO:0031047; GO:0031252; GO:0036464; GO:0045202; GO:0060213; GO:0070934; GO:0071013; GO:0106002; GO:1900152; GO:1900153; GO:1990124; GO:1990904; GO:2000623; GO:2000767 19109 XM_044325882.1 861 653 367 951 491 P29341 5.13e-42 Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1) Mus musculus (Mouse) CRD-mediated mRNA stabilization [GO:0070934]; mRNA processing [GO:0006397]; negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900152]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cytoplasmic translation [GO:2000767]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; RNA splicing [GO:0008380]; RNA-mediated gene silencing [GO:0031047] GO:0000184; GO:0003723; GO:0003729; GO:0003730; GO:0005634; GO:0005737; GO:0005829; GO:0006397; GO:0008022; GO:0008143; GO:0008266; GO:0008380; GO:0010494; GO:0030027; GO:0030425; GO:0031047; GO:0031252; GO:0036464; GO:0045202; GO:0060213; GO:0070934; GO:0071013; GO:0106002; GO:1900152; GO:1900153; GO:1990124; GO:1990904; GO:2000623; GO:2000767 19110 XM_044325882.1 861 653 367 951 491 P29341 4.1e-28 Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1) Mus musculus (Mouse) CRD-mediated mRNA stabilization [GO:0070934]; mRNA processing [GO:0006397]; negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900152]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cytoplasmic translation [GO:2000767]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; RNA splicing [GO:0008380]; RNA-mediated gene silencing [GO:0031047] GO:0000184; GO:0003723; GO:0003729; GO:0003730; GO:0005634; GO:0005737; GO:0005829; GO:0006397; GO:0008022; GO:0008143; GO:0008266; GO:0008380; GO:0010494; GO:0030027; GO:0030425; GO:0031047; GO:0031252; GO:0036464; GO:0045202; GO:0060213; GO:0070934; GO:0071013; GO:0106002; GO:1900152; GO:1900153; GO:1990124; GO:1990904; GO:2000623; GO:2000767 19111 XM_044321367.1 70 3 25 61 125 NA NA NA NA NA NA 19112 XM_029329154.2 357 364 538 458 454 Q8TB37 1.68e-105 Iron-sulfur protein NUBPL (IND1 homolog) (Nucleotide-binding protein-like) (huInd1) Homo sapiens (Human) iron-sulfur cluster assembly [GO:0016226]; mitochondrial respiratory chain complex I assembly [GO:0032981]; mitochondrion morphogenesis [GO:0070584] GO:0005524; GO:0005739; GO:0005759; GO:0005886; GO:0016226; GO:0032981; GO:0046872; GO:0051539; GO:0070584; GO:0140663 19113 XM_044311387.1 130 88 71 139 44 Q4R5Y0 1.48e-34 Uncharacterized protein CFAP68 (cilia and flagella associated protein 68) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0005634 19114 XM_044328958.1 0 8 148 8 40 Q71U34 0 Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8) (Intracellular vitamin D-binding protein 1) Saguinus oedipus (Cotton-top tamarin) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0005524; GO:0005681; GO:0005730; GO:0005886; GO:0006397; GO:0008380; GO:0042470; GO:0140662 19115 XM_029336900.2 59 14 17 0 61 Q9IAK8 8.53e-91 T-box transcription factor TBX5-A (zftbx5a) (T-box protein 5) (zTbx5) Danio rerio (Zebrafish) (Brachydanio rerio) animal organ morphogenesis [GO:0009887]; atrial ventricular junction remodeling [GO:0003294]; atrioventricular canal development [GO:0036302]; atrioventricular valve formation [GO:0003190]; cardiac left ventricle formation [GO:0003218]; cardiac muscle cell differentiation [GO:0055007]; cardiac muscle tissue regeneration [GO:0061026]; cell fate specification [GO:0001708]; DNA-templated transcription [GO:0006351]; embryonic heart tube development [GO:0035050]; embryonic heart tube morphogenesis [GO:0003143]; embryonic pectoral fin morphogenesis [GO:0035118]; heart development [GO:0007507]; heart jogging [GO:0003146]; heart looping [GO:0001947]; heart morphogenesis [GO:0003007]; limb bud formation [GO:0060174]; optic nerve development [GO:0021554]; pattern specification process [GO:0007389]; pectoral fin development [GO:0033339]; pectoral fin morphogenesis [GO:0035138]; pericardium morphogenesis [GO:0003344]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proepicardium development [GO:0003342]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; retina morphogenesis in camera-type eye [GO:0060042] GO:0000978; GO:0000981; GO:0001708; GO:0001947; GO:0003007; GO:0003143; GO:0003146; GO:0003190; GO:0003218; GO:0003294; GO:0003342; GO:0003344; GO:0003700; GO:0005634; GO:0005737; GO:0006351; GO:0006355; GO:0006357; GO:0007389; GO:0007507; GO:0009887; GO:0015629; GO:0021554; GO:0032991; GO:0032993; GO:0033339; GO:0035050; GO:0035118; GO:0035138; GO:0036302; GO:0043565; GO:0045893; GO:0045944; GO:0055007; GO:0060042; GO:0060174; GO:0061026 19116 XM_044324277.1 540 253 314 331 343 Q8NCU4 5.79e-29 Coiled-coil domain-containing protein 191 Homo sapiens (Human) NA NA 19117 XM_044318037.1 9 84 201 249 77 NA NA NA NA NA NA 19118 XM_044313715.1 0 3 0 0 11 NA NA NA NA NA NA 19119 XM_029347532.2 334 324 182 274 397 O64700 2.9e-104 Urease accessory protein G (AtUREG) Arabidopsis thaliana (Mouse-ear cress) nitrogen compound metabolic process [GO:0006807]; positive regulation of catalytic activity [GO:0043085]; urea catabolic process [GO:0043419] GO:0003924; GO:0005525; GO:0006807; GO:0016151; GO:0043085; GO:0043419; GO:0150006 19120 XM_029347935.2 118 61 174 167 104 NA NA NA NA NA NA 19121 XR_003825531.2 14 2 0 0 1 NA NA NA NA NA NA 19122 XR_003824699.2 150 42 59 86 108 NA NA NA NA NA NA 19123 XM_044316307.1 0 0 7 0 1 NA NA NA NA NA NA 19124 XM_029337032.2 0 51 26 47 0 Q8HYZ1 3.63e-100 Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2) Mustela putorius furo (European domestic ferret) (Mustela furo) cardiac muscle cell action potential [GO:0086001]; cellular response to hypoxia [GO:0071456]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005250; GO:0005886; GO:0005901; GO:0008076; GO:0030315; GO:0032809; GO:0034765; GO:0042383; GO:0043197; GO:0043204; GO:0044853; GO:0045211; GO:0046872; GO:0051260; GO:0070161; GO:0071456; GO:0071805; GO:0086001 19125 XR_006395758.1 98 95 131 121 67 NA NA NA NA NA NA 19126 XM_029339819.2 3939 3558 2011 3178 2702 Q8BVE3 4.56e-162 V-type proton ATPase subunit H (V-ATPase subunit H) (Vacuolar proton pump subunit H) Mus musculus (Mouse) endocytosis [GO:0006897]; synaptic vesicle lumen acidification [GO:0097401] GO:0000221; GO:0006897; GO:0016020; GO:0030665; GO:0033176; GO:0033180; GO:0046961; GO:0097401; GO:0098850; GO:1902495; GO:1904949 19127 XM_029333636.2 172 78 0 128 186 Q2KJG1 1.51e-22 Spermatogenesis-associated protein 6 Bos taurus (Bovine) cell differentiation [GO:0030154]; motile cilium assembly [GO:0044458]; spermatogenesis [GO:0007283] GO:0005576; GO:0007283; GO:0030154; GO:0032027; GO:0044458; GO:0097224 19128 XM_044318306.1 80 1 111 108 7 NA NA NA NA NA NA 19129 XM_044326642.1 304 0 295 158 948 Q4V328 8.9e-44 GRIP1-associated protein 1 (GRASP-1) [Cleaved into: GRASP-1 C-terminal chain (30kDa C-terminus form)] Homo sapiens (Human) negative regulation of receptor clustering [GO:1903910]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; regulation of modification of synaptic structure [GO:1905244]; regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0099152]; regulation of recycling endosome localization within postsynapse [GO:0099158] GO:0005085; GO:0005654; GO:0005829; GO:0014069; GO:0030424; GO:0030425; GO:0035255; GO:0042734; GO:0042802; GO:0043025; GO:0043231; GO:0055038; GO:0072562; GO:0098837; GO:0098887; GO:0098978; GO:0098998; GO:0099152; GO:0099158; GO:1903910; GO:1905244 19130 XM_044326642.1 304 0 295 158 948 Q4V328 5.17e-25 GRIP1-associated protein 1 (GRASP-1) [Cleaved into: GRASP-1 C-terminal chain (30kDa C-terminus form)] Homo sapiens (Human) negative regulation of receptor clustering [GO:1903910]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; regulation of modification of synaptic structure [GO:1905244]; regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0099152]; regulation of recycling endosome localization within postsynapse [GO:0099158] GO:0005085; GO:0005654; GO:0005829; GO:0014069; GO:0030424; GO:0030425; GO:0035255; GO:0042734; GO:0042802; GO:0043025; GO:0043231; GO:0055038; GO:0072562; GO:0098837; GO:0098887; GO:0098978; GO:0098998; GO:0099152; GO:0099158; GO:1903910; GO:1905244 19131 XM_044308465.1 1326 1027 966 1231 970 Q8TB40 1.87e-75 (Lyso)-N-acylphosphatidylethanolamine lipase (EC 3.1.1.-) (Alpha/beta hydrolase domain-containing protein 4) (Abhydrolase domain-containing protein 4) (Alpha/beta-hydrolase 4) Homo sapiens (Human) lipid catabolic process [GO:0016042]; lipid homeostasis [GO:0055088]; N-acylphosphatidylethanolamine metabolic process [GO:0070292]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152] GO:0004622; GO:0005739; GO:0005789; GO:0005811; GO:0006654; GO:0016042; GO:0016787; GO:0036152; GO:0042171; GO:0055088; GO:0070292 19132 XM_029336387.2 61 7 25 77 34 NA NA NA NA NA NA 19133 XM_044324394.1 0 9 152 0 193 P35658 1.72e-78 Nuclear pore complex protein Nup214 (214 kDa nucleoporin) (Nucleoporin Nup214) (Protein CAN) Homo sapiens (Human) mitotic cell cycle [GO:0000278]; mRNA export from nucleus [GO:0006406]; nucleocytoplasmic transport [GO:0006913]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; regulation of cell cycle [GO:0051726]; regulation of nucleocytoplasmic transport [GO:0046822]; RNA export from nucleus [GO:0006405] GO:0000278; GO:0005049; GO:0005635; GO:0005643; GO:0005654; GO:0005829; GO:0006405; GO:0006406; GO:0006606; GO:0006611; GO:0006913; GO:0008139; GO:0017056; GO:0046822; GO:0051726; GO:1990876 19134 XM_044324394.1 0 9 152 0 193 P35658 3.02e-33 Nuclear pore complex protein Nup214 (214 kDa nucleoporin) (Nucleoporin Nup214) (Protein CAN) Homo sapiens (Human) mitotic cell cycle [GO:0000278]; mRNA export from nucleus [GO:0006406]; nucleocytoplasmic transport [GO:0006913]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; regulation of cell cycle [GO:0051726]; regulation of nucleocytoplasmic transport [GO:0046822]; RNA export from nucleus [GO:0006405] GO:0000278; GO:0005049; GO:0005635; GO:0005643; GO:0005654; GO:0005829; GO:0006405; GO:0006406; GO:0006606; GO:0006611; GO:0006913; GO:0008139; GO:0017056; GO:0046822; GO:0051726; GO:1990876 19135 XM_029326986.2 3768 4818 3383 5755 6582 Q9ET78 8.04e-62 Junctophilin-2 (JP-2) (Junctophilin type 2) [Cleaved into: Junctophilin-2 N-terminal fragment (JP2NT)] Mus musculus (Mouse) calcium ion homeostasis [GO:0055074]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle tissue development [GO:0055024] GO:0000122; GO:0001046; GO:0001227; GO:0001786; GO:0003677; GO:0005546; GO:0005547; GO:0005634; GO:0005789; GO:0005886; GO:0007204; GO:0010314; GO:0016020; GO:0016529; GO:0030018; GO:0030314; GO:0032266; GO:0033017; GO:0045892; GO:0055024; GO:0055074; GO:0060316; GO:0070273; GO:0070300; GO:0080025 19136 XR_003825067.2 112 30 27 87 97 NA NA NA NA NA NA 19137 XM_029334108.2 231 153 147 130 151 NA NA NA NA NA NA 19138 XM_029348297.2 334 188 210 249 229 NA NA NA NA NA NA 19139 XM_029347483.2 1730 2257 339 1226 736 O04854 1.46e-50 Caffeoyl-CoA O-methyltransferase (EC 2.1.1.104) (Trans-caffeoyl-CoA 3-O-methyltransferase) (CCoAMT) (CCoAOMT) Eucalyptus gunnii (Cider gum) lignin biosynthetic process [GO:0009809]; methylation [GO:0032259] GO:0009809; GO:0032259; GO:0042409; GO:0046872 19140 XM_029347817.2 0 0 0 0 12 Q9NXH9 3.9e-164 tRNA (guanine(26)-N(2))-dimethyltransferase (EC 2.1.1.216) (tRNA 2,2-dimethylguanosine-26 methyltransferase) (tRNA(guanine-26,N(2)-N(2)) methyltransferase) (tRNA(m(2,2)G26)dimethyltransferase) Homo sapiens (Human) tRNA modification [GO:0006400]; tRNA N2-guanine methylation [GO:0002940] GO:0000049; GO:0002940; GO:0003723; GO:0004809; GO:0005634; GO:0005654; GO:0006400; GO:0046872 19141 XM_029343275.2 40 41 29 67 18 NA NA NA NA NA NA 19142 XM_044312004.1 47 42 27 0 27 NA NA NA NA NA NA 19143 XR_006392547.1 26 16 1 24 30 NA NA NA NA NA NA 19144 XM_029346725.2 228 109 202 169 206 NA NA NA NA NA NA 19145 XM_029329840.2 234 104 81 138 118 Q3T906 0 N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (EC 2.7.8.17) (GlcNAc-1-phosphotransferase subunits alpha/beta) (Stealth protein GNPTAB) (UDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/beta) [Cleaved into: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta] Homo sapiens (Human) carbohydrate phosphorylation [GO:0046835]; lysosome organization [GO:0007040]; N-glycan processing to lysosome [GO:0016256]; secretion of lysosomal enzymes [GO:0033299] GO:0000139; GO:0003976; GO:0005509; GO:0005794; GO:0007040; GO:0016256; GO:0033299; GO:0046835; GO:0070622 19146 XM_044309209.1 3 2 7 6 42 NA NA NA NA NA NA 19147 XM_029344075.2 12 3 5 27 29 NA NA NA NA NA NA 19148 XM_044312466.1 175 270 99 71 428 NA NA NA NA NA NA 19149 XM_029343541.2 2612 2765 1864 2587 2445 Q6DC39 1.35e-59 Deubiquitinase DESI2 (EC 3.4.19.12) (Desumoylating isopeptidase 2) (DeSI-2) (PPPDE peptidase domain-containing protein 1) (Protein FAM152A) Danio rerio (Zebrafish) (Brachydanio rerio) convergent extension involved in gastrulation [GO:0060027]; protein deubiquitination [GO:0016579]; protein modification by small protein removal [GO:0070646] GO:0004843; GO:0005737; GO:0016579; GO:0060027; GO:0070646; GO:0101005 19150 XR_006393291.1 12 68 12 53 53 NA NA NA NA NA NA 19151 XM_029331843.2 0 0 0 9 0 Q5RJA1 0 DNA-binding protein RFX6 (Regulatory factor X 6) Danio rerio (Zebrafish) (Brachydanio rerio) endocrine pancreas development [GO:0031018]; glucose homeostasis [GO:0042593]; pancreatic A cell differentiation [GO:0003310]; pancreatic D cell differentiation [GO:0003311]; pancreatic epsilon cell differentiation [GO:0090104]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of insulin secretion [GO:0050796]; regulation of transcription by RNA polymerase II [GO:0006357]; type B pancreatic cell differentiation [GO:0003309] GO:0000976; GO:0000978; GO:0000981; GO:0003309; GO:0003310; GO:0003311; GO:0005634; GO:0006357; GO:0031018; GO:0035774; GO:0042593; GO:0045893; GO:0045944; GO:0050796; GO:0090104 19152 XM_044323383.1 7 0 2 0 81 NA NA NA NA NA NA 19153 XM_044312315.1 0 9 0 0 19 NA NA NA NA NA NA 19154 XM_029350335.2 12 140 32 56 110 NA NA NA NA NA NA 19155 XM_029327592.2 10873 9099 5512 7978 7529 P54996 0 Glucose-6-phosphate 1-dehydrogenase (G6PD) (EC 1.1.1.49) Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) glucose 6-phosphate metabolic process [GO:0051156]; glucose metabolic process [GO:0006006]; NADP metabolic process [GO:0006739]; pentose-phosphate shunt [GO:0006098] GO:0004345; GO:0005829; GO:0006006; GO:0006098; GO:0006739; GO:0050661; GO:0051156 19156 XM_044324141.1 0 8 8 0 0 NA NA NA NA NA NA 19157 XR_006394212.1 13 19 2 28 20 NA NA NA NA NA NA 19158 XR_006396461.1 0 137 0 0 0 Q99570 3.77e-23 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 19159 XM_029325018.2 0 0 0 81 0 NA NA NA NA NA NA 19160 XM_029324180.2 93 129 33 111 132 Q3B8H4 1.25e-63 Rhombotin-1 (LIM domain only protein 1) (LMO-1) Xenopus laevis (African clawed frog) NA GO:0005634; GO:0046872 19161 XM_044313878.1 14 14 1 0 16 NA NA NA NA NA NA 19162 XM_044319084.1 606 211 159 266 173 NA NA NA NA NA NA 19163 XM_029342131.2 333 115 159 234 319 P69478 7.96e-50 Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4S-1) (C4ST-1) (C4ST1) Rattus norvegicus (Rat) apoptotic process [GO:0006915]; carbohydrate biosynthetic process [GO:0016051]; cartilage development [GO:0051216]; chondrocyte development [GO:0002063]; chondroitin sulfate biosynthetic process [GO:0030206]; chondroitin sulfate metabolic process [GO:0030204]; developmental growth [GO:0048589]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; embryonic viscerocranium morphogenesis [GO:0048703]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; polysaccharide localization [GO:0033037]; post-anal tail morphogenesis [GO:0036342]; post-embryonic development [GO:0009791]; proteoglycan biosynthetic process [GO:0030166]; regulation of cell population proliferation [GO:0042127]; respiratory gaseous exchange by respiratory system [GO:0007585]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0000139; GO:0001537; GO:0001701; GO:0002063; GO:0006915; GO:0007179; GO:0007585; GO:0008146; GO:0009791; GO:0016051; GO:0030166; GO:0030204; GO:0030206; GO:0030326; GO:0030512; GO:0033037; GO:0036342; GO:0042127; GO:0042733; GO:0043066; GO:0047756; GO:0048589; GO:0048703; GO:0048704; GO:0050659; GO:0051216 19164 XR_006392102.1 83 293 361 612 170 NA NA NA NA NA NA 19165 XR_006394342.1 29 12 14 0 50 NA NA NA NA NA NA 19166 XM_029337305.2 390 238 325 421 562 Q80YR4 3.49e-86 E3 ubiquitin-protein ligase ZNF598 (EC 2.3.2.27) (Zinc finger protein 598) Mus musculus (Mouse) protein monoubiquitination [GO:0006513]; protein ubiquitination [GO:0016567]; regulation of translation [GO:0006417]; rescue of stalled ribosome [GO:0072344]; ribosome-associated ubiquitin-dependent protein catabolic process [GO:1990116] GO:0005829; GO:0006417; GO:0006513; GO:0016567; GO:0043022; GO:0046872; GO:0061630; GO:0072344; GO:1990116 19167 XM_029335735.2 186 20 213 148 181 Q2KIP6 1e-22 Kappa-type opioid receptor (K-OR-1) (KOR-1) Bos taurus (Bovine) adenylate cyclase-inhibiting opioid receptor signaling pathway [GO:0031635]; defense response to virus [GO:0051607]; G protein-coupled opioid receptor signaling pathway [GO:0038003]; immune response [GO:0006955]; locomotory behavior [GO:0007626]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; regulation of saliva secretion [GO:0046877]; sensory perception of pain [GO:0019233] GO:0004930; GO:0004985; GO:0005654; GO:0005829; GO:0005886; GO:0006955; GO:0007200; GO:0007218; GO:0007626; GO:0016020; GO:0019233; GO:0031635; GO:0038003; GO:0038048; GO:0042277; GO:0042923; GO:0043005; GO:0046877; GO:0051607 19168 XR_006397277.1 30 0 0 22 1 NA NA NA NA NA NA 19169 XM_044324569.1 26 12 13 15 61 NA NA NA NA NA NA 19170 XR_006397587.1 34 0 23 33 51 Q64338 2.05e-118 Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Cam-PDE 1C) (EC 3.1.4.17) Mus musculus (Mouse) negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; response to calcium ion [GO:0051592]; sensory perception of smell [GO:0007608]; signal transduction [GO:0007165] GO:0004114; GO:0004115; GO:0004117; GO:0005516; GO:0005764; GO:0005929; GO:0007165; GO:0007608; GO:0030552; GO:0043025; GO:0046872; GO:0047555; GO:0048101; GO:0051592; GO:0061179 19171 XM_029334065.2 208 245 637 223 206 Q6ZQ03 2.18e-31 Formin-binding protein 4 (Formin-binding protein 30) Mus musculus (Mouse) NA GO:0016607 19172 XM_029343526.2 55 0 0 0 15 NA NA NA NA NA NA 19173 XR_006393482.1 7 2 10 0 13 NA NA NA NA NA NA 19174 XM_029338467.2 203 111 100 162 141 Q99J99 2.32e-97 3-mercaptopyruvate sulfurtransferase (MST) (EC 2.8.1.2) Mus musculus (Mouse) hydrogen sulfide biosynthetic process [GO:0070814]; kidney development [GO:0001822]; liver development [GO:0001889]; spinal cord development [GO:0021510]; transsulfuration [GO:0019346] GO:0001822; GO:0001889; GO:0004792; GO:0005737; GO:0005739; GO:0005743; GO:0005829; GO:0016784; GO:0019346; GO:0021510; GO:0042802; GO:0043005; GO:0045202; GO:0070814 19175 XM_044326567.1 290 1444 460 407 849 NA NA NA NA NA NA 19176 XR_006392234.1 6 2 0 9 22 NA NA NA NA NA NA 19177 XM_029340392.2 2122 0 6 1330 786 Q9NYT6 2.09e-40 Zinc finger protein 226 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 19178 XM_029340392.2 2122 0 6 1330 786 Q9NYT6 4.67e-24 Zinc finger protein 226 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 19179 XM_044309558.1 34 10 12 23 16 NA NA NA NA NA NA 19180 XR_003827012.2 1134 980 532 790 982 NA NA NA NA NA NA 19181 XM_044322903.1 118 22 0 29 39 Q95SX7 6.49e-26 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 19182 XM_044313162.1 274 73 128 180 283 NA NA NA NA NA NA 19183 XM_029334669.2 300 226 249 395 373 E7FAM5 3.35e-132 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 19184 XM_029334669.2 300 226 249 395 373 E7FAM5 8.61e-32 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 19185 XM_044312388.1 1153 308 395 512 1523 Q96DM1 1.06e-37 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 19186 XM_044322136.1 4748 5084 2327 2697 1976 Q5ZI57 7.26e-94 Trafficking protein particle complex subunit 3 Gallus gallus (Chicken) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891] GO:0005783; GO:0005829; GO:0006888; GO:0006891; GO:0030008; GO:0033106 19187 XM_044328336.1 98 43 32 21 211 NA NA NA NA NA NA 19188 XR_003824439.2 62 38 10 78 60 NA NA NA NA NA NA 19189 XM_044318240.1 37 12 14 20 0 Q9HAR2 1.81e-68 Adhesion G protein-coupled receptor L3 (Calcium-independent alpha-latrotoxin receptor 3) (CIRL-3) (Latrophilin-3) (Lectomedin-3) Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; brain development [GO:0007420]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; G protein-coupled receptor signaling pathway [GO:0007186]; neuron migration [GO:0001764]; synapse assembly [GO:0007416] GO:0001764; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007166; GO:0007186; GO:0007189; GO:0007416; GO:0007420; GO:0016020; GO:0030246; GO:0030424; GO:0098742; GO:0098978 19190 XM_044308493.1 228 913 704 693 330 Q60902 5.12e-27 Epidermal growth factor receptor substrate 15-like 1 (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs) (Eps15-related protein) (Eps15R) Mus musculus (Mouse) endocytosis [GO:0006897]; endosomal transport [GO:0016197] GO:0005509; GO:0005634; GO:0006897; GO:0016197; GO:0030132 19191 XM_044323064.1 2 0 0 15 10 NA NA NA NA NA NA 19192 XM_029340940.2 0 18 0 4 0 Q9TRC7 1.45e-173 Amiloride-sensitive amine oxidase [copper-containing] (DAO) (Diamine oxidase) (EC 1.4.3.22) (Amiloride-binding protein 1) (Amine oxidase copper domain-containing protein 1) (Histaminase) Sus scrofa (Pig) amine metabolic process [GO:0009308]; cellular response to azide [GO:0097185]; cellular response to copper ion [GO:0071280]; cellular response to copper ion starvation [GO:0035874]; cellular response to histamine [GO:0071420]; putrescine metabolic process [GO:0009445]; response to antibiotic [GO:0046677] GO:0005507; GO:0005509; GO:0005615; GO:0005886; GO:0005923; GO:0008131; GO:0008201; GO:0008270; GO:0009308; GO:0009445; GO:0035874; GO:0042803; GO:0044877; GO:0046677; GO:0048038; GO:0052597; GO:0052598; GO:0052599; GO:0052600; GO:0070062; GO:0071280; GO:0071420; GO:0097185 19193 XM_044316384.1 3 4 0 6 14 NA NA NA NA NA NA 19194 XM_029353779.2 1547 988 398 1055 340 NA NA NA NA NA NA 19195 XR_006394487.1 0 0 63 27 0 NA NA NA NA NA NA 19196 XM_044320771.1 26 1 50 0 33 Q61555 1.39e-55 Fibrillin-2 [Cleaved into: Placensin] Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; limb morphogenesis [GO:0035108]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030326; GO:0030501; GO:0031012; GO:0035108; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 19197 XM_044320771.1 26 1 50 0 33 Q61555 2.07e-53 Fibrillin-2 [Cleaved into: Placensin] Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; limb morphogenesis [GO:0035108]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030326; GO:0030501; GO:0031012; GO:0035108; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 19198 XM_044320771.1 26 1 50 0 33 Q61555 3.88e-40 Fibrillin-2 [Cleaved into: Placensin] Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; limb morphogenesis [GO:0035108]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030326; GO:0030501; GO:0031012; GO:0035108; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 19199 XM_044320771.1 26 1 50 0 33 Q61555 2.47e-36 Fibrillin-2 [Cleaved into: Placensin] Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; limb morphogenesis [GO:0035108]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030326; GO:0030501; GO:0031012; GO:0035108; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 19200 XM_044320771.1 26 1 50 0 33 Q61555 1.49e-35 Fibrillin-2 [Cleaved into: Placensin] Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; limb morphogenesis [GO:0035108]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030326; GO:0030501; GO:0031012; GO:0035108; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 19201 XM_044320771.1 26 1 50 0 33 Q61555 4.06e-34 Fibrillin-2 [Cleaved into: Placensin] Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; limb morphogenesis [GO:0035108]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030326; GO:0030501; GO:0031012; GO:0035108; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 19202 XM_044320771.1 26 1 50 0 33 Q61555 3.77e-33 Fibrillin-2 [Cleaved into: Placensin] Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; limb morphogenesis [GO:0035108]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030326; GO:0030501; GO:0031012; GO:0035108; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 19203 XM_044320771.1 26 1 50 0 33 Q61555 2e-32 Fibrillin-2 [Cleaved into: Placensin] Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; limb morphogenesis [GO:0035108]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030326; GO:0030501; GO:0031012; GO:0035108; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 19204 XM_044320771.1 26 1 50 0 33 Q61555 4.73e-32 Fibrillin-2 [Cleaved into: Placensin] Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; limb morphogenesis [GO:0035108]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030326; GO:0030501; GO:0031012; GO:0035108; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 19205 XM_044320771.1 26 1 50 0 33 Q61555 5.64e-32 Fibrillin-2 [Cleaved into: Placensin] Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; limb morphogenesis [GO:0035108]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030326; GO:0030501; GO:0031012; GO:0035108; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 19206 XM_044320771.1 26 1 50 0 33 Q61555 1.18e-29 Fibrillin-2 [Cleaved into: Placensin] Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; limb morphogenesis [GO:0035108]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030326; GO:0030501; GO:0031012; GO:0035108; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 19207 XM_044320771.1 26 1 50 0 33 Q61555 3.08e-29 Fibrillin-2 [Cleaved into: Placensin] Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; limb morphogenesis [GO:0035108]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030326; GO:0030501; GO:0031012; GO:0035108; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 19208 XM_044320771.1 26 1 50 0 33 Q61555 2.92e-25 Fibrillin-2 [Cleaved into: Placensin] Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; limb morphogenesis [GO:0035108]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030326; GO:0030501; GO:0031012; GO:0035108; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 19209 XM_044307981.1 1 7 24 69 25 NA NA NA NA NA NA 19210 XR_006396030.1 54 32 0 0 26 NA NA NA NA NA NA 19211 XM_029343096.2 922 748 558 1034 1144 Q6DED0 1.33e-98 Translocating chain-associated membrane protein 1-like 1 Xenopus laevis (African clawed frog) SRP-dependent cotranslational protein targeting to membrane, translocation [GO:0006616] GO:0005789; GO:0006616 19212 XM_044322640.1 0 8 0 0 16 NA NA NA NA NA NA 19213 XM_044306957.1 1981 1391 780 1760 1640 Q7Z401 0 C-myc promoter-binding protein (DENN domain-containing protein 4A) Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355]; regulation of Rab protein signal transduction [GO:0032483] GO:0003677; GO:0005085; GO:0005634; GO:0005829; GO:0006355; GO:0031410; GO:0032483 19214 XM_044306957.1 1981 1391 780 1760 1640 Q7Z401 9.09e-51 C-myc promoter-binding protein (DENN domain-containing protein 4A) Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355]; regulation of Rab protein signal transduction [GO:0032483] GO:0003677; GO:0005085; GO:0005634; GO:0005829; GO:0006355; GO:0031410; GO:0032483 19215 XM_029350699.2 208 587 508 195 968 F1P4W9 0 Cilia- and flagella-associated protein 65 (Coiled-coil domain-containing protein 108) Gallus gallus (Chicken) flagellated sperm motility [GO:0030317]; sperm axoneme assembly [GO:0007288] GO:0001669; GO:0002080; GO:0005737; GO:0005886; GO:0007288; GO:0030317; GO:0036126; GO:0097225 19216 XM_029355929.2 2228 4469 1928 2791 1005 NA NA NA NA NA NA 19217 XR_006391597.1 3 0 3 6 11 Q8CHR6 3.57e-22 Dihydropyrimidine dehydrogenase [NADP(+)] (DHPDHase) (DPD) (EC 1.3.1.2) (Dihydrothymine dehydrogenase) (Dihydrouracil dehydrogenase) Mus musculus (Mouse) beta-alanine biosynthetic process [GO:0019483]; circadian rhythm [GO:0007623]; CMP catabolic process [GO:0006248]; dCMP catabolic process [GO:0006249]; dTMP catabolic process [GO:0046074]; dUMP catabolic process [GO:0046079]; purine nucleobase catabolic process [GO:0006145]; pyrimidine nucleobase catabolic process [GO:0006208]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]; response to xenobiotic stimulus [GO:0009410]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; UMP catabolic process [GO:0046050]; uracil catabolic process [GO:0006212]; uracil metabolic process [GO:0019860] GO:0002058; GO:0005506; GO:0005737; GO:0005829; GO:0006145; GO:0006208; GO:0006210; GO:0006212; GO:0006214; GO:0006248; GO:0006249; GO:0007584; GO:0007623; GO:0009410; GO:0014070; GO:0017113; GO:0019483; GO:0019860; GO:0042802; GO:0042803; GO:0046050; GO:0046074; GO:0046079; GO:0050661; GO:0051536; GO:0051539; GO:0071949 19218 XR_006391597.1 3 0 3 6 11 Q8CHR6 3.57e-22 Dihydropyrimidine dehydrogenase [NADP(+)] (DHPDHase) (DPD) (EC 1.3.1.2) (Dihydrothymine dehydrogenase) (Dihydrouracil dehydrogenase) Mus musculus (Mouse) beta-alanine biosynthetic process [GO:0019483]; circadian rhythm [GO:0007623]; CMP catabolic process [GO:0006248]; dCMP catabolic process [GO:0006249]; dTMP catabolic process [GO:0046074]; dUMP catabolic process [GO:0046079]; purine nucleobase catabolic process [GO:0006145]; pyrimidine nucleobase catabolic process [GO:0006208]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]; response to xenobiotic stimulus [GO:0009410]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; UMP catabolic process [GO:0046050]; uracil catabolic process [GO:0006212]; uracil metabolic process [GO:0019860] GO:0002058; GO:0005506; GO:0005737; GO:0005829; GO:0006145; GO:0006208; GO:0006210; GO:0006212; GO:0006214; GO:0006248; GO:0006249; GO:0007584; GO:0007623; GO:0009410; GO:0014070; GO:0017113; GO:0019483; GO:0019860; GO:0042802; GO:0042803; GO:0046050; GO:0046074; GO:0046079; GO:0050661; GO:0051536; GO:0051539; GO:0071949 19219 XM_029341663.2 634 576 292 378 211 Q9HAN9 5.35e-91 Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 (NMN/NaMN adenylyltransferase 1) (EC 2.7.7.1) (EC 2.7.7.18) (Nicotinamide-nucleotide adenylyltransferase 1) (NMN adenylyltransferase 1) (Nicotinate-nucleotide adenylyltransferase 1) (NaMN adenylyltransferase 1) Homo sapiens (Human) ATP generation from poly-ADP-D-ribose [GO:1990966]; NAD biosynthetic process [GO:0009435]; negative regulation of neuron death [GO:1901215]; nucleotide biosynthetic process [GO:0009165]; response to wounding [GO:0009611] GO:0000309; GO:0004515; GO:0005524; GO:0005634; GO:0005654; GO:0009165; GO:0009435; GO:0009611; GO:0016604; GO:0042802; GO:1901215; GO:1990966 19220 XM_044310096.1 484 109 230 0 115 NA NA NA NA NA NA 19221 XM_044310506.1 3 46 7 4 142 O43854 5.86e-23 EGF-like repeat and discoidin I-like domain-containing protein 3 (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1) Homo sapiens (Human) cell adhesion [GO:0007155]; positive regulation of cell-substrate adhesion [GO:0010811] GO:0005178; GO:0005509; GO:0007155; GO:0010811; GO:0062023; GO:0070062; GO:1903561 19222 XR_006392962.1 41 2 25 5 151 NA NA NA NA NA NA 19223 XM_044317768.1 500 340 142 58 0 P67999 0 Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA) Rattus norvegicus (Rat) aging [GO:0007568]; apoptotic process [GO:0006915]; behavioral fear response [GO:0001662]; cell migration [GO:0016477]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to growth factor stimulus [GO:0071363]; cellular response to hormone stimulus [GO:0032870]; cellular response to insulin stimulus [GO:0032869]; cellular response to organic cyclic compound [GO:0071407]; cellular response to type II interferon [GO:0071346]; G1/S transition of mitotic cell cycle [GO:0000082]; germ cell development [GO:0007281]; long-chain fatty acid import into cell [GO:0044539]; long-term memory [GO:0007616]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of insulin receptor signaling pathway [GO:0046627]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of skeletal muscle tissue growth [GO:0048633]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of translation [GO:0045727]; positive regulation of translational initiation [GO:0045948]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; regulation of glucose import [GO:0046324]; response to amino acid [GO:0043200]; response to electrical stimulus involved in regulation of muscle adaptation [GO:0014878]; response to ethanol [GO:0045471]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to insulin [GO:0032868]; response to leucine [GO:0043201]; response to lipopolysaccharide [GO:0032496]; response to mechanical stimulus [GO:0009612]; response to nutrient [GO:0007584]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to testosterone [GO:0033574]; response to toxic substance [GO:0009636]; response to tumor necrosis factor [GO:0034612]; response to wounding [GO:0009611]; response to xenobiotic stimulus [GO:0009410]; skeletal muscle atrophy [GO:0014732]; skeletal muscle contraction [GO:0003009]; TOR signaling [GO:0031929] GO:0000082; GO:0001662; GO:0003009; GO:0004672; GO:0004674; GO:0004711; GO:0004712; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005741; GO:0005829; GO:0006468; GO:0006915; GO:0007281; GO:0007568; GO:0007584; GO:0007616; GO:0009408; GO:0009410; GO:0009611; GO:0009612; GO:0009636; GO:0009749; GO:0009986; GO:0010033; GO:0010243; GO:0014070; GO:0014732; GO:0014878; GO:0014911; GO:0016477; GO:0018105; GO:0030165; GO:0031667; GO:0031929; GO:0032496; GO:0032868; GO:0032869; GO:0032870; GO:0033574; GO:0033762; GO:0034612; GO:0042277; GO:0042802; GO:0043005; GO:0043066; GO:0043200; GO:0043201; GO:0043434; GO:0043491; GO:0044539; GO:0045202; GO:0045471; GO:0045727; GO:0045931; GO:0045948; GO:0046324; GO:0046627; GO:0048471; GO:0048633; GO:0048661; GO:0050804; GO:0051384; GO:0051721; GO:0071346; GO:0071363; GO:0071407; GO:0071549; GO:0098794; GO:0098978; GO:0106310; GO:2001237 19224 XM_029342245.2 572 196 147 148 308 O88898 9.32e-58 Tumor protein 63 (p63) (Transformation-related protein 63) (TP63) (Tumor protein p73-like) (p73L) Mus musculus (Mouse) anatomical structure formation involved in morphogenesis [GO:0048646]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular senescence [GO:0090398]; chromatin remodeling [GO:0006338]; cloacal septation [GO:0060197]; cranial skeletal system development [GO:1904888]; ectoderm and mesoderm interaction [GO:0007499]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; epidermal cell differentiation [GO:0009913]; epidermal cell division [GO:0010481]; epidermis development [GO:0008544]; epithelial cell development [GO:0002064]; epithelial cell differentiation [GO:0030855]; establishment of planar polarity [GO:0001736]; establishment of skin barrier [GO:0061436]; female genitalia morphogenesis [GO:0048807]; hair follicle development [GO:0001942]; hair follicle morphogenesis [GO:0031069]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; keratinocyte differentiation [GO:0030216]; keratinocyte proliferation [GO:0043616]; morphogenesis of a polarized epithelium [GO:0001738]; multicellular organism aging [GO:0010259]; negative regulation of cellular senescence [GO:2000773]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of keratinocyte differentiation [GO:0045617]; negative regulation of mesoderm development [GO:2000381]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron apoptotic process [GO:0051402]; Notch signaling pathway [GO:0007219]; odontogenesis of dentin-containing tooth [GO:0042475]; pattern specification process [GO:0007389]; polarized epithelial cell differentiation [GO:0030859]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cell cycle G1/S phase transition [GO:1902808]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of fibroblast apoptotic process [GO:2000271]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of somatic stem cell population maintenance [GO:1904674]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; prostate gland development [GO:0030850]; prostatic bud formation [GO:0060513]; protein tetramerization [GO:0051262]; proximal/distal pattern formation [GO:0009954]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of epidermal cell division [GO:0010482]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal system development [GO:0001501]; skin epidermis development [GO:0098773]; skin morphogenesis [GO:0043589]; spermatogenesis [GO:0007283]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; stem cell differentiation [GO:0048863]; stem cell proliferation [GO:0072089]; sympathetic nervous system development [GO:0048485]; transcription by RNA polymerase II [GO:0006366] GO:0000122; GO:0000785; GO:0000977; GO:0000978; GO:0000981; GO:0001228; GO:0001501; GO:0001736; GO:0001738; GO:0001942; GO:0002039; GO:0002064; GO:0003677; GO:0003682; GO:0003684; GO:0003690; GO:0003700; GO:0005634; GO:0005654; GO:0005737; GO:0005791; GO:0006338; GO:0006357; GO:0006366; GO:0006915; GO:0006974; GO:0007219; GO:0007283; GO:0007389; GO:0007499; GO:0008284; GO:0008544; GO:0009887; GO:0009913; GO:0009954; GO:0010259; GO:0010481; GO:0010482; GO:0010838; GO:0019904; GO:0030216; GO:0030326; GO:0030425; GO:0030850; GO:0030855; GO:0030859; GO:0031069; GO:0032991; GO:0033147; GO:0035115; GO:0035116; GO:0036342; GO:0042475; GO:0042771; GO:0042802; GO:0043005; GO:0043281; GO:0043565; GO:0043589; GO:0043616; GO:0045617; GO:0045669; GO:0045747; GO:0045892; GO:0045893; GO:0045944; GO:0046872; GO:0048485; GO:0048646; GO:0048807; GO:0048863; GO:0050699; GO:0051262; GO:0051402; GO:0060197; GO:0060513; GO:0060529; GO:0061436; GO:0072089; GO:0090398; GO:0097371; GO:0098773; GO:1902808; GO:1904674; GO:1904888; GO:2000271; GO:2000381; GO:2000648; GO:2000773; GO:2001235 19225 XM_044327513.1 3 0 0 0 16 NA NA NA NA NA NA 19226 XM_044321750.1 42 9 0 120 222 Q8WZA2 0 Rap guanine nucleotide exchange factor 4 (Exchange factor directly activated by cAMP 2) (Exchange protein directly activated by cAMP 2) (EPAC 2) (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) Homo sapiens (Human) adaptive immune response [GO:0002250]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; calcium-ion regulated exocytosis [GO:0017156]; G protein-coupled receptor signaling pathway [GO:0007186]; insulin secretion [GO:0030073]; positive regulation of GTPase activity [GO:0043547]; positive regulation of insulin secretion [GO:0032024]; Ras protein signal transduction [GO:0007265]; regulation of exocytosis [GO:0017157]; regulation of synaptic vesicle cycle [GO:0098693] GO:0002250; GO:0005085; GO:0005096; GO:0005829; GO:0005886; GO:0007186; GO:0007189; GO:0007265; GO:0016020; GO:0017156; GO:0017157; GO:0030073; GO:0030552; GO:0030674; GO:0031267; GO:0032024; GO:0043547; GO:0098686; GO:0098693 19227 XM_044319737.1 522 353 409 641 603 Q9Y2L5 0 Trafficking protein particle complex subunit 8 (Protein TRS85 homolog) Homo sapiens (Human) COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; protein localization to phagophore assembly site [GO:0034497]; vesicle tethering [GO:0099022] GO:0000407; GO:0005737; GO:0005829; GO:0006888; GO:0007030; GO:0030008; GO:0031410; GO:0034497; GO:0048208; GO:0099022; GO:1990072 19228 XR_006397563.1 16 3 13 0 44 NA NA NA NA NA NA 19229 XM_044320874.1 1756 1335 853 1505 1554 P97379 1.36e-34 Ras GTPase-activating protein-binding protein 2 (G3BP-2) (GAP SH3 domain-binding protein 2) Mus musculus (Mouse) innate immune response [GO:0045087]; mRNA transport [GO:0051028]; positive regulation of stress granule assembly [GO:0062029]; protein homooligomerization [GO:0051260]; small GTPase mediated signal transduction [GO:0007264] GO:0003729; GO:0005829; GO:0007264; GO:0010494; GO:0045087; GO:0051028; GO:0051260; GO:0062029; GO:1990904 19230 XM_029350930.2 295 297 175 238 366 NA NA NA NA NA NA 19231 XM_029356595.2 951 603 445 589 641 Q3T042 2.5e-80 RNA-binding protein NOB1 (EC 3.1.-.-) Bos taurus (Bovine) cleavage involved in rRNA processing [GO:0000469]; maturation of SSU-rRNA [GO:0030490] GO:0000469; GO:0004521; GO:0005634; GO:0030490; GO:0030688; GO:0046872 19232 XR_006397651.1 37 0 0 0 5 NA NA NA NA NA NA 19233 XM_044328106.1 0 0 0 0 82 NA NA NA NA NA NA 19234 XM_029342178.2 444 404 326 513 571 A0A096X8J7 0 NA NA NA NA 19235 XR_006395509.1 141 66 38 37 59 NA NA NA NA NA NA 19236 XM_029357564.2 63 84 93 59 66 Q9H2A2 1.29e-91 2-aminomuconic semialdehyde dehydrogenase (EC 1.2.1.32) (Aldehyde dehydrogenase 12) (Aldehyde dehydrogenase family 8 member A1) Homo sapiens (Human) 9-cis-retinoic acid biosynthetic process [GO:0042904]; L-kynurenine catabolic process [GO:0097053]; retinal metabolic process [GO:0042574]; retinoic acid metabolic process [GO:0042573] GO:0001758; GO:0005829; GO:0016620; GO:0042573; GO:0042574; GO:0042904; GO:0047102; GO:0070062; GO:0097053 19237 XM_029340435.2 0 50 35 123 57 Q96QE2 2.61e-174 Proton myo-inositol cotransporter (H(+)-myo-inositol cotransporter) (Hmit) (H(+)-myo-inositol symporter) (Solute carrier family 2 member 13) Homo sapiens (Human) myo-inositol transport [GO:0015798]; positive regulation of amyloid-beta formation [GO:1902004]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104] GO:0002020; GO:0005365; GO:0005366; GO:0005737; GO:0005886; GO:0015798; GO:0016020; GO:0016324; GO:0022857; GO:0030426; GO:0031090; GO:0042995; GO:0043231; GO:0044297; GO:0051117; GO:0055085; GO:0071944; GO:0097450; GO:0150104; GO:1902004 19238 XM_044326482.1 2 0 0 6 11 NA NA NA NA NA NA 19239 XM_029352894.2 5 5 2 16 10 NA NA NA NA NA NA 19240 XM_044324596.1 127 55 41 104 111 NA NA NA NA NA NA 19241 XR_006395870.1 334 376 106 313 333 NA NA NA NA NA NA 19242 XM_029336716.2 66 23 59 34 30 NA NA NA NA NA NA 19243 XM_044316604.1 674 572 399 687 617 O93295 3.11e-80 Ectonucleoside triphosphate diphosphohydrolase 8 (E-NTPDase 8) (NTPDase 8) (NTPDase8) (EC 3.6.1.5) (Liver ecto-ATP diphosphohydrolase) Gallus gallus (Chicken) nucleoside diphosphate catabolic process [GO:0009134] GO:0004382; GO:0005524; GO:0005886; GO:0009134; GO:0016020; GO:0017110; GO:0045134; GO:0046872 19244 XM_029358222.2 389 264 163 334 604 Q9NX36 3.57e-81 DnaJ homolog subfamily C member 28 Homo sapiens (Human) Golgi organization [GO:0007030]; Golgi vesicle prefusion complex stabilization [GO:0048213]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] GO:0006890; GO:0007030; GO:0017119; GO:0048213 19245 XR_006396137.1 22 16 66 15 18 NA NA NA NA NA NA 19246 XM_029342825.2 0 0 6 0 0 NA NA NA NA NA NA 19247 XM_029333281.2 0 0 78 13 13 C3ZQF9 1.4e-22 QRFP-like peptide receptor Branchiostoma floridae (Florida lancelet) (Amphioxus) cellular response to peptide [GO:1901653]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:1901653 19248 XM_044328763.1 286 164 128 104 122 NA NA NA NA NA NA 19249 XM_029335716.2 672 468 184 548 656 Q8WV93 1.64e-125 AFG1-like ATPase (Lactation elevated protein 1) (EC 3.6.-.-) (Protein AFG1 homolog) Homo sapiens (Human) mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial protein catabolic process [GO:0035694]; mitochondrion organization [GO:0007005] GO:0005524; GO:0005737; GO:0005739; GO:0006123; GO:0007005; GO:0016887; GO:0031966; GO:0035694 19250 XM_044321459.1 692 183 59 539 309 Q90Z06 9.79e-61 Prickle-like protein 1-A (XPk-A) (XpkA) Xenopus laevis (African clawed frog) anterior/posterior axis specification [GO:0009948]; convergent extension involved in gastrulation [GO:0060027]; establishment of planar polarity [GO:0001736] GO:0001736; GO:0005886; GO:0008270; GO:0009948; GO:0060027 19251 XR_006398117.1 128 248 111 219 272 NA NA NA NA NA NA 19252 XM_044318832.1 55 0 0 18 0 Q61107 3.82e-44 Guanylate-binding protein 4 (EC 3.6.5.-) (GTP-binding protein 3) (GBP-3) (GTP-binding protein 4) (GBP-4) (Guanine nucleotide-binding protein 4) (Guanylate-binding protein 3) Mus musculus (Mouse) adhesion of symbiont to host [GO:0044406]; cellular response to interferon-beta [GO:0035458]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to type II interferon [GO:0071346]; defense response to Gram-positive bacterium [GO:0050830]; defense response to protozoan [GO:0042832] GO:0000139; GO:0003924; GO:0005525; GO:0005634; GO:0005794; GO:0005829; GO:0005886; GO:0020005; GO:0031410; GO:0035458; GO:0042802; GO:0042803; GO:0042832; GO:0044406; GO:0048471; GO:0050830; GO:0071346; GO:0071356 19253 XM_029324290.2 64 75 101 18 0 Q2HJ86 0 Tubulin alpha-1D chain (EC 3.6.5.-) [Cleaved into: Detyrosinated tubulin alpha-1D chain] Bos taurus (Bovine) microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278] GO:0000226; GO:0000278; GO:0005200; GO:0005525; GO:0005737; GO:0005874; GO:0016787; GO:0046872 19254 XM_029324290.2 64 75 101 18 0 Q2HJ86 3.28e-48 Tubulin alpha-1D chain (EC 3.6.5.-) [Cleaved into: Detyrosinated tubulin alpha-1D chain] Bos taurus (Bovine) microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278] GO:0000226; GO:0000278; GO:0005200; GO:0005525; GO:0005737; GO:0005874; GO:0016787; GO:0046872 19255 XM_044308069.1 0 40 93 57 0 Q8BQH6 1.12e-22 CUB domain-containing protein 2 Mus musculus (Mouse) NA GO:0005576 19256 XM_029357070.2 714 452 404 666 673 Q16891 2.97e-64 MICOS complex subunit MIC60 (Cell proliferation-inducing gene 4/52 protein) (Mitochondrial inner membrane protein) (Mitofilin) (p87/89) Homo sapiens (Human) cristae formation [GO:0042407]; inner mitochondrial membrane organization [GO:0007007]; mitochondrial calcium ion homeostasis [GO:0051560]; neuron cellular homeostasis [GO:0070050] GO:0001401; GO:0003723; GO:0005739; GO:0005743; GO:0005758; GO:0007007; GO:0016020; GO:0042407; GO:0044284; GO:0051560; GO:0061617; GO:0070050; GO:0140275 19257 XM_044317698.1 0 0 0 0 11 Q9HC77 9.32e-88 Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1) Homo sapiens (Human) astral microtubule nucleation [GO:0030954]; cell division [GO:0051301]; centriole elongation [GO:0061511]; centriole replication [GO:0007099]; cilium assembly [GO:0060271]; microtubule nucleation [GO:0007020]; microtubule polymerization [GO:0046785]; motile cilium assembly [GO:0044458]; non-motile cilium assembly [GO:1905515]; positive regulation of centriole elongation [GO:1903724]; positive regulation of centriole replication [GO:0046601]; positive regulation of establishment of protein localization [GO:1904951]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of non-motile cilium assembly [GO:1902857]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of spindle assembly [GO:1905832]; regulation of centriole replication [GO:0046599]; regulation of mitotic spindle organization [GO:0060236]; smoothened signaling pathway [GO:0007224] GO:0003713; GO:0005634; GO:0005737; GO:0005813; GO:0005814; GO:0005829; GO:0005874; GO:0007020; GO:0007099; GO:0007224; GO:0008275; GO:0015631; GO:0019901; GO:0019904; GO:0030954; GO:0036064; GO:0042802; GO:0043015; GO:0044458; GO:0046427; GO:0046599; GO:0046601; GO:0046785; GO:0051301; GO:0060236; GO:0060271; GO:0061511; GO:0120099; GO:1900087; GO:1902857; GO:1903724; GO:1904951; GO:1905515; GO:1905832 19258 XM_044317698.1 0 0 0 0 11 Q9HC77 6.18e-34 Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1) Homo sapiens (Human) astral microtubule nucleation [GO:0030954]; cell division [GO:0051301]; centriole elongation [GO:0061511]; centriole replication [GO:0007099]; cilium assembly [GO:0060271]; microtubule nucleation [GO:0007020]; microtubule polymerization [GO:0046785]; motile cilium assembly [GO:0044458]; non-motile cilium assembly [GO:1905515]; positive regulation of centriole elongation [GO:1903724]; positive regulation of centriole replication [GO:0046601]; positive regulation of establishment of protein localization [GO:1904951]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of non-motile cilium assembly [GO:1902857]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of spindle assembly [GO:1905832]; regulation of centriole replication [GO:0046599]; regulation of mitotic spindle organization [GO:0060236]; smoothened signaling pathway [GO:0007224] GO:0003713; GO:0005634; GO:0005737; GO:0005813; GO:0005814; GO:0005829; GO:0005874; GO:0007020; GO:0007099; GO:0007224; GO:0008275; GO:0015631; GO:0019901; GO:0019904; GO:0030954; GO:0036064; GO:0042802; GO:0043015; GO:0044458; GO:0046427; GO:0046599; GO:0046601; GO:0046785; GO:0051301; GO:0060236; GO:0060271; GO:0061511; GO:0120099; GO:1900087; GO:1902857; GO:1903724; GO:1904951; GO:1905515; GO:1905832 19259 XM_029343230.2 68 65 22 213 238 NA NA NA NA NA NA 19260 XM_044312351.1 311 214 152 302 341 O94864 1.15e-30 STAGA complex 65 subunit gamma (Adenocarcinoma antigen ART1) (SPTF-associated factor 65 gamma) (STAF65gamma) (Suppressor of Ty 7-like) Homo sapiens (Human) histone H3 acetylation [GO:0043966]; maintenance of protein location in nucleus [GO:0051457]; monoubiquitinated histone deubiquitination [GO:0035521]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA repair [GO:0006282]; regulation of RNA splicing [GO:0043484] GO:0000124; GO:0003713; GO:0005634; GO:0005654; GO:0006282; GO:0035521; GO:0035522; GO:0043484; GO:0043966; GO:0045893; GO:0046982; GO:0051457 19261 XM_044325721.1 0 5 4 16 0 NA NA NA NA NA NA 19262 XM_044307338.1 0 0 0 0 20 Q0V8S9 1.23e-25 Contactin-associated protein-like 5 (Cell recognition molecule Caspr5) Gallus gallus (Chicken) cell adhesion [GO:0007155] GO:0007155; GO:0016020 19263 XM_029352481.2 15 17 2 15 10 Q8BUY9 2.29e-110 Geranylgeranyl transferase type-1 subunit beta (EC 2.5.1.59) (Geranylgeranyl transferase type I subunit beta) (GGTase-I-beta) (Type I protein geranyl-geranyltransferase subunit beta) Mus musculus (Mouse) negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; protein geranylgeranylation [GO:0018344]; protein prenylation [GO:0018342]; response to cytokine [GO:0034097] GO:0004661; GO:0004662; GO:0005953; GO:0008270; GO:0008284; GO:0018342; GO:0018344; GO:0034097; GO:0036094; GO:0042277; GO:0045787; GO:0051771; GO:1901363 19264 XM_029340936.2 964 925 453 770 992 NA NA NA NA NA NA 19265 XR_003828333.2 2885 2731 2235 2483 2492 NA NA NA NA NA NA 19266 XM_044315730.1 0 0 0 0 36 NA NA NA NA NA NA 19267 XM_029347930.2 1422 1294 842 1214 1193 Q9BZV1 7.17e-83 UBX domain-containing protein 6 (UBX domain-containing protein 1) Homo sapiens (Human) endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; macroautophagy [GO:0016236] GO:0005634; GO:0005737; GO:0005765; GO:0005768; GO:0005815; GO:0005829; GO:0016236; GO:0019898; GO:0031901; GO:0031902; GO:0032510; GO:0032991; GO:0036503; GO:0070062 19268 XM_044315911.1 156 88 62 87 84 NA NA NA NA NA NA 19269 XM_044328980.1 416 299 250 303 460 NA NA NA NA NA NA 19270 XM_044313795.1 147 0 0 0 0 Q7RTR2 1.08e-72 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 19271 XM_044313795.1 147 0 0 0 0 Q7RTR2 1.7e-66 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 19272 XM_044313795.1 147 0 0 0 0 Q7RTR2 7.97e-66 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 19273 XM_044313795.1 147 0 0 0 0 Q7RTR2 5.16e-63 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 19274 XM_044313795.1 147 0 0 0 0 Q7RTR2 5.43e-55 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 19275 XR_003827572.2 87 80 78 49 225 NA NA NA NA NA NA 19276 XM_029340049.2 601 245 279 305 258 NA NA NA NA NA NA 19277 XM_029357267.2 0 0 3 71 25 NA NA NA NA NA NA 19278 XM_029355428.2 153 83 68 82 179 Q5UQN4 1.17e-43 Uncharacterized protein L432 Acanthamoeba polyphaga mimivirus (APMV) NA GO:0016787 19279 XM_044321878.1 867 789 606 815 783 Q6TGS6 0 Tyrosine--tRNA ligase, cytoplasmic (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to DNA damage stimulus [GO:0006974]; tyrosyl-tRNA aminoacylation [GO:0006437] GO:0000049; GO:0004831; GO:0005524; GO:0005634; GO:0005737; GO:0006437; GO:0006974 19280 XM_044320671.1 0 0 7 0 0 NA NA NA NA NA NA 19281 XM_029328197.2 291 133 226 162 98 NA NA NA NA NA NA 19282 XM_044317324.1 30 7 34 9 6 NA NA NA NA NA NA 19283 XM_029335421.2 0 0 14 0 55 NA NA NA NA NA NA 19284 XR_006397930.1 190 2 13 1 81 NA NA NA NA NA NA 19285 XM_044328566.1 1693 1230 825 1456 1289 P32780 2.4e-140 General transcription factor IIH subunit 1 (Basic transcription factor 2 62 kDa subunit) (BTF2 p62) (General transcription factor IIH polypeptide 1) (TFIIH basal transcription factor complex p62 subunit) Homo sapiens (Human) DNA repair [GO:0006281]; hormone-mediated signaling pathway [GO:0009755]; nucleotide-excision repair [GO:0006289]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366] GO:0000079; GO:0000439; GO:0003682; GO:0005654; GO:0005675; GO:0006281; GO:0006289; GO:0006360; GO:0006366; GO:0009755; GO:0045893; GO:0046966; GO:0070816 19286 XM_044317935.1 5 0 0 14 0 P07098 1.97e-135 Gastric triacylglycerol lipase (GL) (Gastric lipase) (EC 3.1.1.3) Homo sapiens (Human) lipid catabolic process [GO:0016042]; malate metabolic process [GO:0006108]; triglyceride metabolic process [GO:0006641] GO:0004806; GO:0005576; GO:0005739; GO:0006108; GO:0006641; GO:0008289; GO:0016042; GO:0016615; GO:0043231 19287 XR_003822946.2 94 158 149 103 120 NA NA NA NA NA NA 19288 XM_044310099.1 270 391 322 150 1077 NA NA NA NA NA NA 19289 XM_044310829.1 349 985 466 0 0 NA NA NA NA NA NA 19290 XM_044307101.1 214 732 107 178 265 Q58DM8 4.67e-128 Enoyl-CoA hydratase, mitochondrial (mECH) (mECH1) (EC 4.2.1.17) (EC 5.3.3.8) (Enoyl-CoA hydratase 1) (ECHS1) (Short-chain enoyl-CoA hydratase) (SCEH) Bos taurus (Bovine) fatty acid beta-oxidation [GO:0006635] GO:0004165; GO:0004300; GO:0005739; GO:0005759; GO:0006635; GO:0043956; GO:0120092 19291 XM_044308565.1 0 0 0 0 27 NA NA NA NA NA NA 19292 XM_044323663.1 7 144 11 12 314 NA NA NA NA NA NA 19293 XM_029332325.2 336 313 262 434 409 P70711 2.67e-38 Ubiquitin-conjugating enzyme E2 D2B (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme D2B) (Ubiquitin carrier protein D2B) (Ubiquitin-conjugating enzyme E2(17)KB 2B) (Ubiquitin-conjugating enzyme E2-17 kDa 2B) (Ubiquitin-protein ligase D2B) Rattus norvegicus (Rat) cellular response to arsenite(3-) [GO:1903841]; cellular response to cadmium ion [GO:0071276]; protein K11-linked ubiquitination [GO:0070979]; protein K27-linked ubiquitination [GO:0044314]; protein K29-linked ubiquitination [GO:0035519]; protein K48-linked ubiquitination [GO:0070936]; protein K6-linked ubiquitination [GO:0085020]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567] GO:0000209; GO:0004842; GO:0005524; GO:0005634; GO:0016567; GO:0035519; GO:0044314; GO:0061631; GO:0070534; GO:0070936; GO:0070979; GO:0071276; GO:0085020; GO:1903841 19294 XR_003827367.2 394 8156 5114 4538 7468 NA NA NA NA NA NA 19295 XM_044321821.1 36 58 18 9 125 NA NA NA NA NA NA 19296 XM_044315532.1 0 0 0 16 0 NA NA NA NA NA NA 19297 XR_006391917.1 990 1091 8 987 294 NA NA NA NA NA NA 19298 XM_029340123.2 143 23 19 97 61 P97503 2.17e-32 Homeobox protein Nkx-3.2 (Bagpipe homeobox protein homolog 1) (Homeobox protein NK-3 homolog B) Mus musculus (Mouse) animal organ development [GO:0048513]; animal organ formation [GO:0048645]; cell differentiation [GO:0030154]; determination of left/right symmetry [GO:0007368]; digestive system development [GO:0055123]; embryonic skeletal system development [GO:0048706]; intestinal epithelial cell development [GO:0060576]; middle ear morphogenesis [GO:0042474]; negative regulation of apoptotic process [GO:0043066]; negative regulation of chondrocyte differentiation [GO:0032331]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas development [GO:0031016]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal system development [GO:0001501]; skeletal system morphogenesis [GO:0048705]; spleen development [GO:0048536] GO:0000122; GO:0000978; GO:0000981; GO:0001227; GO:0001501; GO:0005634; GO:0005654; GO:0006357; GO:0007368; GO:0030154; GO:0031016; GO:0032331; GO:0042474; GO:0043066; GO:0048513; GO:0048536; GO:0048645; GO:0048705; GO:0048706; GO:0055123; GO:0060576; GO:1990837 19299 XR_006395281.1 0 0 0 11 5 NA NA NA NA NA NA 19300 XM_044307550.1 70 0 164 0 156 Q502W6 0 von Willebrand factor A domain-containing protein 3B (VWA domain-containing protein 3B) Homo sapiens (Human) NA GO:0005654; GO:0005829 19301 XM_029349424.2 698 457 472 959 763 Q14CM0 2.48e-84 FERM and PDZ domain-containing protein 4 (PDZ domain-containing protein 10) (PSD-95-interacting regulator of spine morphogenesis) (Preso) Homo sapiens (Human) positive regulation of synapse structural plasticity [GO:0051835] GO:0005546; GO:0005856; GO:0032991; GO:0043197; GO:0051835 19302 XM_029349424.2 698 457 472 959 763 Q14CM0 2.48e-84 FERM and PDZ domain-containing protein 4 (PDZ domain-containing protein 10) (PSD-95-interacting regulator of spine morphogenesis) (Preso) Homo sapiens (Human) positive regulation of synapse structural plasticity [GO:0051835] GO:0005546; GO:0005856; GO:0032991; GO:0043197; GO:0051835 19303 XM_029327101.2 392 137 226 268 540 Q92540 2.83e-105 Nonsense-mediated mRNA decay factor SMG7 (SMG-7 homolog) (hSMG-7) Homo sapiens (Human) mRNA export from nucleus [GO:0006406]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of dephosphorylation [GO:0035303] GO:0000184; GO:0005634; GO:0005697; GO:0005737; GO:0005829; GO:0006406; GO:0035303; GO:0042162; GO:0045111; GO:0051721; GO:0070034 19304 XM_044320268.1 27 4 15 26 19 Q28CH8 1.13e-78 Protein YIPF6 (YIP1 family member 6) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888] GO:0000138; GO:0000139; GO:0005797; GO:0005802; GO:0006888 19305 XM_044311228.1 10 59 30 0 37 P21328 5.63e-28 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 19306 XM_029327674.2 0 20 0 0 9 NA NA NA NA NA NA 19307 XM_044316989.1 441 147 294 580 191 NA NA NA NA NA NA 19308 XR_006398150.1 117 208 0 0 163 NA NA NA NA NA NA 19309 XM_029339768.2 587 466 109 1774 783 NA NA NA NA NA NA 19310 XM_029335032.2 22 17 7 31 10 O94766 7.37e-81 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 (EC 2.4.1.135) (Beta-1,3-glucuronyltransferase 3) (Glucuronosyltransferase I) (GlcAT-I) (UDP-GlcUA:Gal beta-1,3-Gal-R glucuronyltransferase) (GlcUAT-I) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; chondroitin sulfate proteoglycan biosynthetic process [GO:0050650]; dermatan sulfate proteoglycan biosynthetic process [GO:0050651]; glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; positive regulation of catalytic activity [GO:0043085]; positive regulation of intracellular protein transport [GO:0090316]; protein glycosylation [GO:0006486] GO:0000139; GO:0005794; GO:0005801; GO:0005975; GO:0006024; GO:0006486; GO:0015012; GO:0015018; GO:0015020; GO:0016020; GO:0043085; GO:0046872; GO:0050650; GO:0050651; GO:0070062; GO:0072542; GO:0090316 19311 XM_029332974.2 2899 1690 948 1644 1489 A6NFN9 3.19e-62 Protein ANKUB1 (Ankyrin repeat and ubiquitin domain-containing 1) Homo sapiens (Human) NA NA 19312 XM_044319463.1 1 163 3 28 470 NA NA NA NA NA NA 19313 XM_029333614.2 1042 899 599 984 788 Q9NA75 1.01e-37 Trimeric intracellular cation channel type 1B.1 (TRIC-1B.1) (TRIC-B1) Caenorhabditis elegans NA GO:0005267; GO:0005789; GO:0042802 19314 XM_044329248.1 0 0 0 25 0 NA NA NA NA NA NA 19315 XM_044313646.1 0 23 22 37 18 NA NA NA NA NA NA 19316 XM_029344846.2 330 81 184 135 240 Q6DIV6 1.06e-62 Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Solute carrier family 32 member 1) (Vesicular GABA transporter) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) beta-alanine transport [GO:0001762]; gamma-aminobutyric acid import [GO:0051939]; gamma-aminobutyric acid transport [GO:0015812]; glycine transport [GO:0015816]; neurotransmitter transport [GO:0006836] GO:0001762; GO:0006836; GO:0008021; GO:0015185; GO:0015187; GO:0015812; GO:0015816; GO:0030659; GO:0042995; GO:0051939; GO:0098793; GO:0140799; GO:0140800 19317 XR_006396217.1 26 0 39 0 193 NA NA NA NA NA NA 19318 XM_044311390.1 0 0 9 0 0 NA NA NA NA NA NA 19319 XM_044320534.1 974 831 521 631 887 Q9QXG2 1.71e-146 Rab proteins geranylgeranyltransferase component A 1 (Choroideremia protein homolog) (Rab escort protein 1) (REP-1) Mus musculus (Mouse) blood vessel development [GO:0001568]; protein geranylgeranylation [GO:0018344]; protein targeting to membrane [GO:0006612]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192] GO:0001568; GO:0005092; GO:0005096; GO:0005634; GO:0005737; GO:0005829; GO:0005968; GO:0006612; GO:0007264; GO:0016192; GO:0018344; GO:0031267; GO:0044877 19320 XM_029339676.2 781 606 291 706 710 Q5REF6 4.17e-159 Ectonucleoside triphosphate diphosphohydrolase 7 (NTPDase 7) (EC 3.6.1.15) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) CTP catabolic process [GO:0006254]; GTP metabolic process [GO:0046039]; nucleobase-containing small molecule catabolic process [GO:0034656]; UTP catabolic process [GO:0046052] GO:0003924; GO:0006254; GO:0017111; GO:0030659; GO:0034656; GO:0043273; GO:0046039; GO:0046052; GO:0046872 19321 XM_044312563.1 5 257 138 140 265 NA NA NA NA NA NA 19322 XM_044306765.1 0 264 0 151 22 Q90Y54 0 Protein jagged-1b (Jagged1b) (Jagged3) Danio rerio (Zebrafish) (Brachydanio rerio) auditory receptor cell development [GO:0060117]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; cranial skeletal system development [GO:1904888]; dorsal/ventral pattern formation [GO:0009953]; exocrine pancreas development [GO:0031017]; face morphogenesis [GO:0060325]; fin regeneration [GO:0031101]; inner ear morphogenesis [GO:0042472]; intrahepatic bile duct development [GO:0035622]; liver development [GO:0001889]; Notch signaling pathway [GO:0007219]; otolith morphogenesis [GO:0032474]; pancreas development [GO:0031016]; semicircular canal development [GO:0060872]; semicircular canal morphogenesis [GO:0048752]; thyroid gland development [GO:0030878] GO:0001889; GO:0005112; GO:0005509; GO:0005886; GO:0007219; GO:0009953; GO:0030878; GO:0031016; GO:0031017; GO:0031101; GO:0032474; GO:0035622; GO:0042472; GO:0048752; GO:0060117; GO:0060325; GO:0060351; GO:0060872; GO:1904888 19323 XM_044306765.1 0 264 0 151 22 Q90Y54 3.25e-163 Protein jagged-1b (Jagged1b) (Jagged3) Danio rerio (Zebrafish) (Brachydanio rerio) auditory receptor cell development [GO:0060117]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; cranial skeletal system development [GO:1904888]; dorsal/ventral pattern formation [GO:0009953]; exocrine pancreas development [GO:0031017]; face morphogenesis [GO:0060325]; fin regeneration [GO:0031101]; inner ear morphogenesis [GO:0042472]; intrahepatic bile duct development [GO:0035622]; liver development [GO:0001889]; Notch signaling pathway [GO:0007219]; otolith morphogenesis [GO:0032474]; pancreas development [GO:0031016]; semicircular canal development [GO:0060872]; semicircular canal morphogenesis [GO:0048752]; thyroid gland development [GO:0030878] GO:0001889; GO:0005112; GO:0005509; GO:0005886; GO:0007219; GO:0009953; GO:0030878; GO:0031016; GO:0031017; GO:0031101; GO:0032474; GO:0035622; GO:0042472; GO:0048752; GO:0060117; GO:0060325; GO:0060351; GO:0060872; GO:1904888 19324 XM_044306765.1 0 264 0 151 22 Q90Y54 3.05e-24 Protein jagged-1b (Jagged1b) (Jagged3) Danio rerio (Zebrafish) (Brachydanio rerio) auditory receptor cell development [GO:0060117]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; cranial skeletal system development [GO:1904888]; dorsal/ventral pattern formation [GO:0009953]; exocrine pancreas development [GO:0031017]; face morphogenesis [GO:0060325]; fin regeneration [GO:0031101]; inner ear morphogenesis [GO:0042472]; intrahepatic bile duct development [GO:0035622]; liver development [GO:0001889]; Notch signaling pathway [GO:0007219]; otolith morphogenesis [GO:0032474]; pancreas development [GO:0031016]; semicircular canal development [GO:0060872]; semicircular canal morphogenesis [GO:0048752]; thyroid gland development [GO:0030878] GO:0001889; GO:0005112; GO:0005509; GO:0005886; GO:0007219; GO:0009953; GO:0030878; GO:0031016; GO:0031017; GO:0031101; GO:0032474; GO:0035622; GO:0042472; GO:0048752; GO:0060117; GO:0060325; GO:0060351; GO:0060872; GO:1904888 19325 XR_003827092.2 70 86 172 131 164 NA NA NA NA NA NA 19326 XM_029337842.2 173 258 109 160 173 Q9M1R1 1.83e-56 L-cysteine desulfhydrase (EC 4.4.1.28) (AtL-CDes1) (L-CDes1) (AtLCD) Arabidopsis thaliana (Mouse-ear cress) L-cysteine catabolic process to pyruvate [GO:0019450] GO:0019450; GO:0080146 19327 XM_044314922.1 59 0 26 0 6 NA NA NA NA NA NA 19328 XM_044327181.1 32 44 13 45 40 NA NA NA NA NA NA 19329 XM_044308425.1 0 14 0 110 0 Q8BG58 4.54e-73 Transmembrane prolyl 4-hydroxylase (P4H-TM) (EC 1.14.11.29) (Hypoxia-inducible factor prolyl hydroxylase 4) (HIF-PH4) (HIF-prolyl hydroxylase 4) (HPH-4) Mus musculus (Mouse) peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; regulation of erythrocyte differentiation [GO:0045646] GO:0004656; GO:0005506; GO:0005509; GO:0005783; GO:0005789; GO:0016706; GO:0018401; GO:0031418; GO:0045646 19330 XR_006395493.1 1658 1839 1022 1626 1032 NA NA NA NA NA NA 19331 XM_029358712.2 65 98 25 254 133 Q9GYZ0 0 Kinesin-like protein KIF15 (Kinesin-related protein KRP180) Strongylocentrotus purpuratus (Purple sea urchin) microtubule-based movement [GO:0007018]; regulation of mitotic spindle assembly [GO:1901673] GO:0003777; GO:0005524; GO:0005737; GO:0005819; GO:0005871; GO:0005874; GO:0007018; GO:0008017; GO:0016887; GO:1901673 19332 XM_044310123.1 0 37 103 0 0 NA NA NA NA NA NA 19333 XR_006398083.1 8 4 42 4 15 NA NA NA NA NA NA 19334 XM_044313271.1 133 147 63 238 184 Q68EA5 9.97e-51 Zinc finger protein 57 (Zinc finger protein 424) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000977; GO:0000981; GO:0005634; GO:0006357; GO:0046872 19335 XM_044313271.1 133 147 63 238 184 Q68EA5 7.32e-44 Zinc finger protein 57 (Zinc finger protein 424) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000977; GO:0000981; GO:0005634; GO:0006357; GO:0046872 19336 XM_044313271.1 133 147 63 238 184 Q68EA5 4.14e-43 Zinc finger protein 57 (Zinc finger protein 424) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000977; GO:0000981; GO:0005634; GO:0006357; GO:0046872 19337 XM_044313271.1 133 147 63 238 184 Q68EA5 4.72e-43 Zinc finger protein 57 (Zinc finger protein 424) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000977; GO:0000981; GO:0005634; GO:0006357; GO:0046872 19338 XM_044313271.1 133 147 63 238 184 Q68EA5 7.57e-43 Zinc finger protein 57 (Zinc finger protein 424) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000977; GO:0000981; GO:0005634; GO:0006357; GO:0046872 19339 XM_044313271.1 133 147 63 238 184 Q68EA5 4.77e-36 Zinc finger protein 57 (Zinc finger protein 424) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000977; GO:0000981; GO:0005634; GO:0006357; GO:0046872 19340 XM_044313271.1 133 147 63 238 184 Q68EA5 2.38e-32 Zinc finger protein 57 (Zinc finger protein 424) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000977; GO:0000981; GO:0005634; GO:0006357; GO:0046872 19341 XM_044313271.1 133 147 63 238 184 Q68EA5 1.13e-27 Zinc finger protein 57 (Zinc finger protein 424) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000977; GO:0000981; GO:0005634; GO:0006357; GO:0046872 19342 XM_029330009.2 255 187 254 260 252 Q8IV35 0 WD repeat-containing protein 49 Homo sapiens (Human) NA NA 19343 XM_029347465.2 191 0 129 190 239 NA NA NA NA NA NA 19344 XM_029347099.2 29 0 0 0 102 NA NA NA NA NA NA 19345 XR_006391546.1 6 34 0 0 0 NA NA NA NA NA NA 19346 XM_044312330.1 79 1 5 108 76 P36887 7.29e-28 cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11) Sus scrofa (Pig) cellular response to heat [GO:0034605]; negative regulation of meiotic cell cycle process involved in oocyte maturation [GO:1904145]; protein phosphorylation [GO:0006468] GO:0001669; GO:0004674; GO:0004679; GO:0004691; GO:0005524; GO:0005634; GO:0005737; GO:0005739; GO:0005886; GO:0006468; GO:0034605; GO:0036126; GO:0042585; GO:0048471; GO:0106310; GO:1904145 19347 XM_029340865.2 181 128 63 129 111 O75486 9.47e-62 Transcription initiation protein SPT3 homolog (SPT3-like protein) Homo sapiens (Human) histone acetylation [GO:0016573]; histone H3 acetylation [GO:0043966]; monoubiquitinated histone deubiquitination [GO:0035521]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA repair [GO:0006282]; regulation of DNA-templated transcription [GO:0006355]; regulation of RNA splicing [GO:0043484]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366] GO:0000124; GO:0003713; GO:0005634; GO:0005654; GO:0006282; GO:0006355; GO:0006357; GO:0006366; GO:0016573; GO:0033276; GO:0035521; GO:0035522; GO:0043484; GO:0043966; GO:0045893; GO:0046982 19348 XM_029341107.2 26 11 25 14 26 Q8N8K9 3.67e-22 Uncharacterized protein KIAA1958 Homo sapiens (Human) NA NA 19349 XM_029334720.2 78 82 65 47 99 NA NA NA NA NA NA 19350 XR_006393290.1 492 584 386 1045 652 NA NA NA NA NA NA 19351 XR_006392655.1 10 8 16 24 70 NA NA NA NA NA NA 19352 XM_044328783.1 0 0 0 10 0 Q09575 1.31e-32 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 19353 XM_029339929.2 20998 23167 12689 23239 10109 Q642H2 5.67e-21 cAMP-responsive element-binding protein-like 2 Danio rerio (Zebrafish) (Brachydanio rerio) cell differentiation [GO:0030154]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of glucose import [GO:0046326]; positive regulation of lipid biosynthetic process [GO:0046889]; regulation of DNA-templated transcription [GO:0006355] GO:0003677; GO:0003700; GO:0005634; GO:0006355; GO:0030154; GO:0045600; GO:0045893; GO:0046326; GO:0046889 19354 XM_029329214.2 181 521 1406 1577 1286 Q15059 1.7e-74 Bromodomain-containing protein 3 (RING3-like protein) Homo sapiens (Human) chromatin remodeling [GO:0006338]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000785; GO:0003682; GO:0005634; GO:0006338; GO:0006355; GO:0006357; GO:0070577 19355 XM_029329214.2 181 521 1406 1577 1286 Q15059 1.47e-40 Bromodomain-containing protein 3 (RING3-like protein) Homo sapiens (Human) chromatin remodeling [GO:0006338]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000785; GO:0003682; GO:0005634; GO:0006338; GO:0006355; GO:0006357; GO:0070577 19356 XM_044322609.1 117 107 84 132 0 Q9D2I5 0 LisH domain-containing protein ARMC9 Mus musculus (Mouse) cilium assembly [GO:0060271]; positive regulation of smoothened signaling pathway [GO:0045880] GO:0005737; GO:0005814; GO:0005929; GO:0036064; GO:0045880; GO:0060271; GO:0097542 19357 XM_029328650.2 0 24 0 0 8 Q5R6J1 1.03e-87 Sodium-dependent neutral amino acid transporter B(0)AT1 (Solute carrier family 6 member 19) (System B(0) neutral amino acid transporter AT1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0015175; GO:0015293; GO:0016324 19358 XM_044321084.1 0 0 39 0 0 Q9NZJ4 0 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 19359 XM_029334686.2 3379 2721 2077 3869 3474 Q6UFZ9 3.66e-91 14-3-3 protein beta/alpha-1 (Protein 14-3-3B1) Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) NA GO:0005737 19360 XR_006395283.1 129 4 6 69 51 NA NA NA NA NA NA 19361 XM_044321945.1 61 0 670 130 0 NA NA NA NA NA NA 19362 XM_044324558.1 0 43 8 8 46 NA NA NA NA NA NA 19363 XM_029331907.2 8333 8879 4384 8049 7217 O42387 2.21e-68 40S ribosomal protein S24 Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) translation [GO:0006412] GO:0003735; GO:0005840; GO:0006412; GO:1990904 19364 XR_006392439.1 112 68 71 84 199 NA NA NA NA NA NA 19365 XM_029356729.2 1614 1362 1349 1404 1111 Q5RBR8 7.17e-30 Eukaryotic translation initiation factor 4H (eIF-4H) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003723; GO:0003743; GO:0048471 19366 XM_029339735.2 448 474 522 647 754 Q6GLQ4 7.94e-26 Serine/threonine-protein phosphatase 1 regulatory subunit 10 Xenopus laevis (African clawed frog) NA GO:0004864; GO:0005634; GO:0046872 19367 XM_029339735.2 448 474 522 647 754 Q6GLQ4 2.31e-25 Serine/threonine-protein phosphatase 1 regulatory subunit 10 Xenopus laevis (African clawed frog) NA GO:0004864; GO:0005634; GO:0046872 19368 XM_044318115.1 138 0 0 207 94 NA NA NA NA NA NA 19369 XM_044321220.1 4 0 6 0 32 NA NA NA NA NA NA 19370 XR_003828234.2 59 44 30 72 74 NA NA NA NA NA NA 19371 XM_044327018.1 19 0 10 26 18 NA NA NA NA NA NA 19372 XR_006395059.1 8 6 35 18 9 NA NA NA NA NA NA 19373 XM_029356407.2 0 0 20 9 0 Q9NRM2 3.19e-118 Zinc finger protein 277 (Nuclear receptor-interacting factor 4) Homo sapiens (Human) cellular response to hydrogen peroxide [GO:0070301]; regulation of cellular senescence [GO:2000772] GO:0000978; GO:0005634; GO:0046872; GO:0070301; GO:2000772 19374 XM_044312965.1 1 45 12 29 13 Q8K3Z0 4.19e-34 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 19375 XM_029328894.2 186 194 97 246 135 NA NA NA NA NA NA 19376 XM_029335937.2 2768 4009 1939 2768 839 O14508 1.24e-27 Suppressor of cytokine signaling 2 (SOCS-2) (Cytokine-inducible SH2 protein 2) (CIS-2) (STAT-induced STAT inhibitor 2) (SSI-2) Homo sapiens (Human) cellular response to hormone stimulus [GO:0032870]; growth hormone receptor signaling pathway [GO:0060396]; intracellular signal transduction [GO:0035556]; lactation [GO:0007595]; mammary gland alveolus development [GO:0060749]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; phosphatidylinositol phosphate biosynthetic process [GO:0046854]; positive regulation of neuron differentiation [GO:0045666]; protein ubiquitination [GO:0016567]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of cell growth [GO:0001558]; regulation of signal transduction [GO:0009966]; response to estradiol [GO:0032355] GO:0001558; GO:0005131; GO:0005159; GO:0005737; GO:0005829; GO:0005942; GO:0007259; GO:0007595; GO:0008269; GO:0009966; GO:0016567; GO:0032355; GO:0032870; GO:0035556; GO:0040015; GO:0043066; GO:0045666; GO:0046426; GO:0046854; GO:0046935; GO:0060396; GO:0060749 19377 XM_044321985.1 244 154 203 192 321 Q96AY4 5.02e-67 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19378 XM_044321985.1 244 154 203 192 321 Q96AY4 1.88e-66 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19379 XM_044321985.1 244 154 203 192 321 Q96AY4 8.7e-66 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19380 XM_044321985.1 244 154 203 192 321 Q96AY4 5.27e-63 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19381 XM_044321985.1 244 154 203 192 321 Q96AY4 1.62e-61 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19382 XM_044321985.1 244 154 203 192 321 Q96AY4 7.05e-55 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19383 XM_044321985.1 244 154 203 192 321 Q96AY4 1.7e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19384 XM_029324014.2 294 613 392 601 548 Q8CHT3 7.02e-82 Integrator complex subunit 5 (Int5) Mus musculus (Mouse) snRNA 3'-end processing [GO:0034472]; snRNA processing [GO:0016180] GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0016180; GO:0031965; GO:0032039; GO:0034472 19385 XM_029351495.2 33 15 35 0 47 Q91ZV3 1.47e-24 Discoidin, CUB and LCCL domain-containing protein 2 (Endothelial and smooth muscle cell-derived neuropilin-like protein) Mus musculus (Mouse) negative regulation of cell growth [GO:0030308]; wound healing [GO:0042060] GO:0005886; GO:0009986; GO:0030308; GO:0038023; GO:0042060 19386 XM_029342475.2 146 83 103 151 136 NA NA NA NA NA NA 19387 XM_044325268.1 1054 315 286 361 1584 P35555 8.68e-46 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 19388 XM_044325268.1 1054 315 286 361 1584 P35555 2.19e-44 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 19389 XM_044325268.1 1054 315 286 361 1584 P35555 9.45e-41 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 19390 XM_044325268.1 1054 315 286 361 1584 P35555 8.68e-35 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 19391 XM_044325268.1 1054 315 286 361 1584 P35555 1.49e-34 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 19392 XM_044325268.1 1054 315 286 361 1584 P35555 1.08e-31 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 19393 XM_044325268.1 1054 315 286 361 1584 P35555 1.1e-31 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 19394 XM_044325268.1 1054 315 286 361 1584 P35555 6.79e-27 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 19395 XM_044325268.1 1054 315 286 361 1584 P35555 4.95e-26 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 19396 XM_044325268.1 1054 315 286 361 1584 P35555 1.04e-25 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 19397 XM_044325268.1 1054 315 286 361 1584 P35555 1.33e-24 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 19398 XM_044325268.1 1054 315 286 361 1584 P35555 4.98e-24 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 19399 XM_044325268.1 1054 315 286 361 1584 P35555 1.16e-23 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 19400 XM_044325268.1 1054 315 286 361 1584 P35555 1.86e-23 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 19401 XM_044325268.1 1054 315 286 361 1584 P35555 3.43e-22 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 19402 XM_044325268.1 1054 315 286 361 1584 P35555 3.79e-22 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 19403 XM_029350185.2 0 88 0 49 205 NA NA NA NA NA NA 19404 XM_029338876.2 140 93 66 0 248 NA NA NA NA NA NA 19405 XM_029350443.2 181 87 131 187 187 NA NA NA NA NA NA 19406 XM_044316625.1 868 56 0 1116 64 Q8RWL6 5.5e-29 Serine/threonine-protein kinase STY17 (EC 2.7.11.1) (Serine/threonine/tyrosine-protein kinase 17) Arabidopsis thaliana (Mouse-ear cress) chloroplast organization [GO:0009658]; protein phosphorylation [GO:0006468] GO:0004674; GO:0004712; GO:0005524; GO:0005829; GO:0006468; GO:0009658; GO:0106310 19407 XM_044316625.1 868 56 0 1116 64 Q8RWL6 8.03e-29 Serine/threonine-protein kinase STY17 (EC 2.7.11.1) (Serine/threonine/tyrosine-protein kinase 17) Arabidopsis thaliana (Mouse-ear cress) chloroplast organization [GO:0009658]; protein phosphorylation [GO:0006468] GO:0004674; GO:0004712; GO:0005524; GO:0005829; GO:0006468; GO:0009658; GO:0106310 19408 XM_029338809.2 0 0 0 0 19 NA NA NA NA NA NA 19409 XM_029343824.2 1294 2023 1844 2298 2 Q90XC2 1.21e-132 Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never in mitosis A-related kinase 8) (NimA-related protein kinase 8) Danio rerio (Zebrafish) (Brachydanio rerio) animal organ morphogenesis [GO:0009887]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; determination of heart left/right asymmetry [GO:0061371]; heart looping [GO:0001947]; pronephros development [GO:0048793]; pronephros formation [GO:0072116]; protein phosphorylation [GO:0006468]; renal tubule development [GO:0061326] GO:0001947; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005929; GO:0006468; GO:0007059; GO:0009887; GO:0046872; GO:0048793; GO:0051301; GO:0061326; GO:0061371; GO:0072116; GO:0106310 19410 XR_006396027.1 0 1 3 5 9 NA NA NA NA NA NA 19411 XM_044326021.1 2336 1726 1298 2740 2550 Q8AY68 2.65e-50 SHC-transforming protein 1 (Src homology 2 domain-containing-transforming protein C1) (SH2 domain protein C1) (p60Shc) Xenopus laevis (African clawed frog) intracellular signal transduction [GO:0035556] GO:0005737; GO:0035556 19412 XM_044326021.1 2336 1726 1298 2740 2550 Q8AY68 3.11e-29 SHC-transforming protein 1 (Src homology 2 domain-containing-transforming protein C1) (SH2 domain protein C1) (p60Shc) Xenopus laevis (African clawed frog) intracellular signal transduction [GO:0035556] GO:0005737; GO:0035556 19413 XM_044322521.1 26 0 0 3 7 NA NA NA NA NA NA 19414 XM_029341992.2 73 41 55 34 167 Q5TYP4 5.5e-103 Uncharacterized protein C1orf112 homolog Danio rerio (Zebrafish) (Brachydanio rerio) NA NA 19415 XM_044307373.1 79 49 65 0 136 NA NA NA NA NA NA 19416 XM_029356225.2 424 412 316 332 511 Q91WQ5 5.71e-141 TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (TAF5L) (PCAF-associated factor 65 beta) (PAF65-beta) Mus musculus (Mouse) histone acetylation [GO:0016573]; histone H3 acetylation [GO:0043966]; monoubiquitinated histone deubiquitination [GO:0035521]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA repair [GO:0006282]; regulation of DNA-templated transcription [GO:0006355]; regulation of RNA splicing [GO:0043484]; regulation of somatic stem cell population maintenance [GO:1904672]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000123; GO:0000124; GO:0003713; GO:0005634; GO:0006282; GO:0006355; GO:0006357; GO:0016573; GO:0016607; GO:0033276; GO:0035521; GO:0035522; GO:0036464; GO:0043484; GO:0043966; GO:0045893; GO:1904672 19417 XM_029342268.2 130 114 163 172 120 P15129 6.1e-129 Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1) (Cytochrome P450 L-2) (Cytochrome P450 isozyme 5) Rattus norvegicus (Rat) biphenyl metabolic process [GO:0018879] GO:0004497; GO:0005506; GO:0005789; GO:0018879; GO:0020037; GO:0043231; GO:0070330; GO:1901363 19418 XM_044322281.1 432 631 256 343 406 Q5T089 1.49e-87 MORN repeat-containing protein 1 Homo sapiens (Human) NA NA 19419 XM_044318470.1 343 689 254 563 299 Q9JIF3 4e-101 Solute carrier family 2, facilitated glucose transporter member 8 (Glucose transporter type 8) (GLUT-8) (Glucose transporter type X1) Mus musculus (Mouse) dehydroascorbic acid transport [GO:0070837]; fructose transmembrane transport [GO:0015755]; galactose transmembrane transport [GO:0015757]; glucose metabolic process [GO:0006006]; glucose transmembrane transport [GO:1904659]; insulin receptor signaling pathway [GO:0008286]; male meiosis I [GO:0007141]; response to hypoxia [GO:0001666]; transmembrane transport [GO:0055085] GO:0001666; GO:0005353; GO:0005354; GO:0005355; GO:0005536; GO:0005886; GO:0006006; GO:0007141; GO:0008021; GO:0008286; GO:0015284; GO:0015755; GO:0015757; GO:0016020; GO:0022857; GO:0030659; GO:0033300; GO:0055085; GO:0070837; GO:1904659 19420 XM_029343892.2 38 90 81 203 0 Q9VBW3 5.14e-59 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 19421 XM_044323050.1 64 227 110 106 109 Q08DY9 1.04e-30 Caspase-3 (CASP-3) (EC 3.4.22.56) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12] Bos taurus (Bovine) positive regulation of amyloid-beta formation [GO:1902004]; proteolysis [GO:0006508]; regulation of protein stability [GO:0031647] GO:0004175; GO:0005737; GO:0006508; GO:0031647; GO:0097153; GO:0097199; GO:0097200; GO:1902004 19422 XM_044318076.1 375 39 89 81 81 NA NA NA NA NA NA 19423 XM_044314768.1 0 77 0 18 0 NA NA NA NA NA NA 19424 XM_029347922.2 4 4 8 64 25 NA NA NA NA NA NA 19425 XM_044329227.1 0 0 0 33 0 Q29RY4 2.58e-78 Zinc phosphodiesterase ELAC protein 1 (EC 3.1.26.11) (ElaC homolog protein 1) (Ribonuclease Z 1) (RNase Z 1) (tRNA 3 endonuclease 1) (tRNase Z 1) Bos taurus (Bovine) tRNA 3'-trailer cleavage [GO:0042779] GO:0005634; GO:0005654; GO:0005829; GO:0042779; GO:0042781; GO:0046872 19426 XM_029342871.2 1 0 1 0 13 NA NA NA NA NA NA 19427 XM_029329351.2 422 50 366 60 374 O08873 8.34e-159 MAP kinase-activating death domain protein (Rab3 GDP/GTP exchange factor) (RabGEF) (Rab3 GDP/GTP exchange protein) (RabGEP) Rattus norvegicus (Rat) anterograde synaptic vesicle transport [GO:0048490]; execution phase of apoptosis [GO:0097194]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of growth hormone secretion [GO:0060125]; negative regulation of pancreatic amylase secretion [GO:1902277]; positive regulation of MAPK cascade [GO:0043410]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of extrinsic apoptotic signaling pathway [GO:2001236]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of Rab protein signal transduction [GO:0032483] GO:0005085; GO:0005634; GO:0005829; GO:0005886; GO:0008021; GO:0016020; GO:0030424; GO:0032483; GO:0042981; GO:0043410; GO:0045202; GO:0048490; GO:0051726; GO:0060125; GO:0097194; GO:1902041; GO:1902277; GO:1904115; GO:2001234; GO:2001236 19428 XM_029329351.2 422 50 366 60 374 O08873 1.46e-123 MAP kinase-activating death domain protein (Rab3 GDP/GTP exchange factor) (RabGEF) (Rab3 GDP/GTP exchange protein) (RabGEP) Rattus norvegicus (Rat) anterograde synaptic vesicle transport [GO:0048490]; execution phase of apoptosis [GO:0097194]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of growth hormone secretion [GO:0060125]; negative regulation of pancreatic amylase secretion [GO:1902277]; positive regulation of MAPK cascade [GO:0043410]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of extrinsic apoptotic signaling pathway [GO:2001236]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of Rab protein signal transduction [GO:0032483] GO:0005085; GO:0005634; GO:0005829; GO:0005886; GO:0008021; GO:0016020; GO:0030424; GO:0032483; GO:0042981; GO:0043410; GO:0045202; GO:0048490; GO:0051726; GO:0060125; GO:0097194; GO:1902041; GO:1902277; GO:1904115; GO:2001234; GO:2001236 19429 XM_029329044.2 3570 2359 1925 2853 2864 Q14678 1.32e-53 KN motif and ankyrin repeat domain-containing protein 1 (Ankyrin repeat domain-containing protein 15) (Kidney ankyrin repeat-containing protein) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cell population proliferation [GO:0008283]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of cell migration [GO:0030336]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lamellipodium morphogenesis [GO:2000393]; negative regulation of neuron projection development [GO:0010977]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of ruffle assembly [GO:1900028]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025]; podocyte cell migration [GO:0090521]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Wnt signaling pathway [GO:0030177]; positive regulation of wound healing [GO:0090303]; regulation of establishment of cell polarity [GO:2000114]; regulation of Rho protein signal transduction [GO:0035023] GO:0005634; GO:0005737; GO:0005856; GO:0005886; GO:0008013; GO:0008283; GO:0010977; GO:0030036; GO:0030177; GO:0030336; GO:0030837; GO:0032587; GO:0035023; GO:0035024; GO:0046627; GO:0090263; GO:0090303; GO:0090521; GO:1900025; GO:1900028; GO:2000114; GO:2000393 19430 XM_044325352.1 224 106 107 189 317 P07911 2.3e-26 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Homo sapiens (Human) antibacterial innate immune response [GO:0140367]; apoptotic signaling pathway [GO:0097190]; autophagy [GO:0006914]; cellular calcium ion homeostasis [GO:0006874]; cellular chloride ion homeostasis [GO:0030644]; cellular defense response [GO:0006968]; cellular phosphate ion homeostasis [GO:0030643]; cellular response to unfolded protein [GO:0034620]; cellular sodium ion homeostasis [GO:0006883]; chaperone-mediated protein folding [GO:0061077]; citric acid secretion [GO:0046720]; collecting duct development [GO:0072044]; connective tissue replacement [GO:0097709]; creatinine homeostasis [GO:0097273]; defense response to Gram-negative bacterium [GO:0050829]; endoplasmic reticulum organization [GO:0007029]; glomerular filtration [GO:0003094]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; juxtaglomerular apparatus development [GO:0072051]; leukocyte cell-cell adhesion [GO:0007159]; lipid metabolic process [GO:0006629]; metanephric ascending thin limb development [GO:0072218]; metanephric distal convoluted tubule development [GO:0072221]; metanephric thick ascending limb development [GO:0072233]; micturition [GO:0060073]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell population proliferation [GO:0008285]; neutrophil migration [GO:1990266]; organ or tissue specific immune response [GO:0002251]; peptidyl-threonine phosphorylation [GO:0018107]; potassium ion homeostasis [GO:0055075]; protein localization to vacuole [GO:0072665]; protein transport into plasma membrane raft [GO:0044861]; regulation of blood pressure [GO:0008217]; regulation of protein transport [GO:0051223]; regulation of urine volume [GO:0035809]; renal sodium ion absorption [GO:0070294]; renal urate salt excretion [GO:0097744]; renal water homeostasis [GO:0003091]; response to lipopolysaccharide [GO:0032496]; response to water deprivation [GO:0009414]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; ubiquitin-dependent ERAD pathway [GO:0030433]; urate transport [GO:0015747]; urea transmembrane transport [GO:0071918] GO:0000922; GO:0002251; GO:0003091; GO:0003094; GO:0005201; GO:0005509; GO:0005615; GO:0005783; GO:0005796; GO:0005929; GO:0006629; GO:0006874; GO:0006883; GO:0006914; GO:0006954; GO:0006968; GO:0007029; GO:0007157; GO:0007159; GO:0008217; GO:0008285; GO:0008380; GO:0009410; GO:0009414; GO:0009986; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0018107; GO:0019864; GO:0019898; GO:0030433; GO:0030643; GO:0030644; GO:0032496; GO:0033209; GO:0033555; GO:0034620; GO:0035809; GO:0044861; GO:0046720; GO:0050829; GO:0051223; GO:0055075; GO:0060073; GO:0060170; GO:0061077; GO:0070062; GO:0070294; GO:0071918; GO:0072044; GO:0072051; GO:0072218; GO:0072221; GO:0072233; GO:0072665; GO:0097190; GO:0097273; GO:0097709; GO:0097744; GO:0140367; GO:1990266 19431 XR_003822842.2 54 48 75 59 79 NA NA NA NA NA NA 19432 XM_044323794.1 67 6 4 0 72 Q9VL06 5.96e-24 E3 ubiquitin-protein ligase Ufd4 (EC 2.3.2.26) (Ubiquitin fusion-degradation 4-like) Drosophila melanogaster (Fruit fly) anatomical structure development [GO:0048856]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000209; GO:0005634; GO:0006511; GO:0016607; GO:0032436; GO:0043161; GO:0046872; GO:0048856; GO:0061630; GO:0070373; GO:0070534 19433 XM_044310756.1 20 21 0 51 0 O70244 9.97e-50 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 19434 XM_044310756.1 20 21 0 51 0 O70244 3e-46 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 19435 XM_044310756.1 20 21 0 51 0 O70244 2.4e-40 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 19436 XM_044310756.1 20 21 0 51 0 O70244 7.21e-38 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 19437 XM_044310756.1 20 21 0 51 0 O70244 3.1e-37 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 19438 XM_044310756.1 20 21 0 51 0 O70244 2.59e-33 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 19439 XM_044310756.1 20 21 0 51 0 O70244 3.45e-30 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 19440 XM_044310756.1 20 21 0 51 0 O70244 3.78e-29 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 19441 XM_044310756.1 20 21 0 51 0 O70244 9.32e-28 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 19442 XM_044310756.1 20 21 0 51 0 O70244 4.57e-27 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 19443 XM_044310756.1 20 21 0 51 0 O70244 9.4e-27 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 19444 XM_044310756.1 20 21 0 51 0 O70244 1.97e-26 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 19445 XM_044310756.1 20 21 0 51 0 O70244 5.94e-26 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 19446 XM_044310756.1 20 21 0 51 0 O70244 1.93e-24 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 19447 XM_044310756.1 20 21 0 51 0 O70244 5.25e-24 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 19448 XM_044310756.1 20 21 0 51 0 O70244 1.6e-22 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 19449 XM_044318815.1 53 23 38 61 67 NA NA NA NA NA NA 19450 XM_029349164.2 260 427 11 213 296 Q9CPV7 1.75e-91 Palmitoyltransferase ZDHHC6 (EC 2.3.1.225) (Stearoyltransferase ZDHHC6) (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 6) (DHHC-6) Mus musculus (Mouse) peptidyl-L-cysteine S-palmitoylation [GO:0018230]; positive regulation of mitochondrial fusion [GO:0010636]; protein palmitoylation [GO:0018345]; protein stearoylation [GO:0140438]; protein targeting to membrane [GO:0006612] GO:0005783; GO:0005789; GO:0005794; GO:0006612; GO:0010636; GO:0016409; GO:0018230; GO:0018345; GO:0019706; GO:0140438; GO:0140439 19451 XM_029349097.2 2539 1271 1106 2089 1803 O60941 1.69e-164 Dystrobrevin beta (DTN-B) (Beta-dystrobrevin) Homo sapiens (Human) neuron differentiation [GO:0030182]; synaptic signaling [GO:0099536] GO:0005634; GO:0005737; GO:0005886; GO:0008270; GO:0009925; GO:0014069; GO:0030182; GO:0030425; GO:0045202; GO:0060077; GO:0099536 19452 XM_044314773.1 0 11 0 26 36 NA NA NA NA NA NA 19453 XM_029332975.2 257 32 11 0 0 Q9H0B8 5.68e-31 Cysteine-rich secretory protein LCCL domain-containing 2 (Cysteine-rich secretory protein 11) (CRISP-11) (LCCL domain-containing cysteine-rich secretory protein 2) Homo sapiens (Human) extracellular matrix organization [GO:0030198]; face morphogenesis [GO:0060325]; lung development [GO:0030324] GO:0005539; GO:0005576; GO:0005615; GO:0008201; GO:0030133; GO:0030198; GO:0030324; GO:0031012; GO:0034774; GO:0060325; GO:0070062; GO:1904813 19454 XM_029348544.2 2013 1792 1173 1712 1731 NA NA NA NA NA NA 19455 XR_006397180.1 49 0 15 5 16 NA NA NA NA NA NA 19456 XM_044314573.1 1482 1933 859 2607 1895 Q3TZZ7 4.57e-84 Extended synaptotagmin-2 (E-Syt2) Mus musculus (Mouse) endocytosis [GO:0006897]; endoplasmic reticulum-plasma membrane tethering [GO:0061817]; lipid transport [GO:0006869] GO:0005509; GO:0005544; GO:0005789; GO:0005829; GO:0005886; GO:0006869; GO:0006897; GO:0008429; GO:0031210; GO:0031234; GO:0035091; GO:0042802; GO:0044232; GO:0061817; GO:0140268 19457 XM_044329045.1 20 15 40 26 121 NA NA NA NA NA NA 19458 XM_044326377.1 210 208 153 161 183 NA NA NA NA NA NA 19459 XM_044326009.1 45 25 21 7 16 NA NA NA NA NA NA 19460 XM_029337276.2 776 1225 1074 1587 1514 NA NA NA NA NA NA 19461 XM_029345663.2 930 191 212 346 25 NA NA NA NA NA NA 19462 XR_006393548.1 230 232 239 319 337 NA NA NA NA NA NA 19463 XM_029342971.2 701 887 844 1138 1215 Q9JID6 0 Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3) (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain acyl-CoA synthetase 1) (LACS 1) (Palmitoyl-CoA ligase) (Phytanate--CoA ligase) (EC 6.2.1.24) Cavia porcellus (Guinea pig) long-chain fatty acid metabolic process [GO:0001676]; very long-chain fatty acid metabolic process [GO:0000038] GO:0000038; GO:0001676; GO:0004467; GO:0005524; GO:0005741; GO:0005778; GO:0005783; GO:0005789; GO:0047676; GO:0050197; GO:0070251 19464 XR_006394386.1 40 141 13 30 27 NA NA NA NA NA NA 19465 XM_029357311.2 954 626 292 729 977 Q9CPV4 1.03e-138 Glyoxalase domain-containing protein 4 Mus musculus (Mouse) NA GO:0005739 19466 XM_029356631.2 6 1 1 0 0 NA NA NA NA NA NA 19467 XM_044321659.1 96 68 55 129 57 NA NA NA NA NA NA 19468 XM_044327378.1 35 35 0 26 14 NA NA NA NA NA NA 19469 XM_029348476.2 125 159 0 217 67 P55199 5.02e-29 RNA polymerase II elongation factor ELL (Eleven-nineteen lysine-rich leukemia protein) Homo sapiens (Human) in utero embryonic development [GO:0001701]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of transcription by RNA polymerase III [GO:0045945]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; snRNA transcription by RNA polymerase II [GO:0042795]; snRNA transcription by RNA polymerase III [GO:0042796]; transcription elongation by RNA polymerase II promoter [GO:0006368] GO:0000791; GO:0000987; GO:0001701; GO:0005654; GO:0005829; GO:0006368; GO:0008023; GO:0015030; GO:0016604; GO:0016607; GO:0019902; GO:0032786; GO:0032968; GO:0035363; GO:0042795; GO:0042796; GO:0045945 19470 XM_044328847.1 6 6 14 15 11 NA NA NA NA NA NA 19471 XM_029341494.2 49263 50653 17992 36772 24028 P49706 4.72e-100 G1/S-specific cyclin-D2 Gallus gallus (Chicken) cell division [GO:0051301]; mitotic cell cycle phase transition [GO:0044772]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079] GO:0000079; GO:0000307; GO:0005634; GO:0005737; GO:0016538; GO:0031965; GO:0044772; GO:0051301; GO:1900087 19472 XM_044326957.1 154 73 75 75 202 Q9BYN7 2.21e-37 Zinc finger protein 341 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0000978; GO:0000981; GO:0001216; GO:0003677; GO:0005634; GO:0006355; GO:0046872 19473 XR_006395054.1 274 114 61 191 78 NA NA NA NA NA NA 19474 XM_029340258.2 0 22 45 0 0 NA NA NA NA NA NA 19475 XM_029347293.2 2 0 13 0 1 NA NA NA NA NA NA 19476 XM_029345183.2 30 41 37 22 48 NA NA NA NA NA NA 19477 XR_006392562.1 1619 1812 1099 2180 1657 Q8BXN7 2.48e-37 Protein phosphatase 1K, mitochondrial (EC 3.1.3.16) (Protein phosphatase 2C isoform kappa) (PP2C-kappa) Mus musculus (Mouse) peptidyl-threonine dephosphorylation [GO:0035970] GO:0004722; GO:0005739; GO:0005759; GO:0017018; GO:0035970; GO:0046872 19478 XR_006392562.1 1619 1812 1099 2180 1657 Q8BXN7 8.11e-31 Protein phosphatase 1K, mitochondrial (EC 3.1.3.16) (Protein phosphatase 2C isoform kappa) (PP2C-kappa) Mus musculus (Mouse) peptidyl-threonine dephosphorylation [GO:0035970] GO:0004722; GO:0005739; GO:0005759; GO:0017018; GO:0035970; GO:0046872 19479 XM_029340277.2 0 0 0 195 140 Q5RA50 1.13e-26 Protein FAM124A Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA NA 19480 XM_044308202.1 25 86 59 120 68 NA NA NA NA NA NA 19481 XR_003823965.2 808 817 543 692 686 NA NA NA NA NA NA 19482 XM_029355856.2 151 198 57 144 103 NA NA NA NA NA NA 19483 XM_029343963.2 271 320 210 337 252 Q1AE95 1.87e-48 Putative transmembrane protein 183BP (Transmembrane protein 183B pseudogene) Homo sapiens (Human) regulation of protein stability [GO:0031647] GO:0016020; GO:0019005; GO:0031647 19484 XM_029326991.2 713 590 423 757 563 Q6ZN84 4.1e-71 Coiled-coil domain-containing protein 81 Homo sapiens (Human) NA GO:0005737; GO:0005813 19485 XM_029326991.2 713 590 423 757 563 Q6ZN84 8.25e-63 Coiled-coil domain-containing protein 81 Homo sapiens (Human) NA GO:0005737; GO:0005813 19486 XR_006397171.1 90 175 48 68 54 NA NA NA NA NA NA 19487 XR_006392037.1 0 11 13 7 28 NA NA NA NA NA NA 19488 XM_044325566.1 27 12 5 0 12 NA NA NA NA NA NA 19489 XM_044319103.1 142 298 88 366 171 NA NA NA NA NA NA 19490 XM_029358332.2 103 36 75 30 173 NA NA NA NA NA NA 19491 XM_029326266.2 2637 1670 1571 3298 3258 O77633 4.29e-136 Disintegrin and metalloproteinase domain-containing protein 10 (ADAM 10) (EC 3.4.24.81) (Kuzbanian protein homolog) (Mammalian disintegrin-metalloprotease) (CD antigen CD156c) Sus scrofa (Pig) adherens junction organization [GO:0034332]; cochlea development [GO:0090102]; constitutive protein ectodomain proteolysis [GO:0051089]; epidermal growth factor receptor ligand maturation [GO:0038004]; in utero embryonic development [GO:0001701]; membrane protein ectodomain proteolysis [GO:0006509]; monocyte activation [GO:0042117]; negative regulation of cell adhesion [GO:0007162]; negative regulation of gene expression [GO:0010629]; Notch signaling pathway [GO:0007219]; pore complex assembly [GO:0046931]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of T cell chemotaxis [GO:0010820]; postsynapse organization [GO:0099173]; protein catabolic process at postsynapse [GO:0140249]; protein phosphorylation [GO:0006468]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of Notch signaling pathway [GO:0008593]; regulation of postsynapse organization [GO:0099175]; regulation of vasculature development [GO:1901342]; response to tumor necrosis factor [GO:0034612]; toxin transport [GO:1901998] GO:0000139; GO:0001701; GO:0004175; GO:0004222; GO:0005634; GO:0005798; GO:0005886; GO:0005912; GO:0006468; GO:0006509; GO:0007162; GO:0007219; GO:0008284; GO:0008593; GO:0009986; GO:0010629; GO:0010820; GO:0014069; GO:0017124; GO:0019901; GO:0030136; GO:0030307; GO:0030424; GO:0030425; GO:0034332; GO:0034612; GO:0038004; GO:0042117; GO:0042803; GO:0046872; GO:0046930; GO:0046931; GO:0051089; GO:0070573; GO:0090102; GO:0097038; GO:0097060; GO:0097197; GO:0098696; GO:0098978; GO:0099173; GO:0099175; GO:0140249; GO:1901342; GO:1901998; GO:1902945 19492 XM_029327284.2 95 0 23 40 0 Q6NZ04 7.84e-117 Homeobox protein six1b (Homeobox protein six1a) (Sine oculis homeobox homolog 1a) (Sine oculis homeobox homolog 1b) Danio rerio (Zebrafish) (Brachydanio rerio) adenohypophysis development [GO:0021984]; apoptotic process [GO:0006915]; extraocular skeletal muscle development [GO:0002074]; inner ear development [GO:0048839]; peripheral nervous system neuron development [GO:0048935]; pharyngeal muscle development [GO:0043282]; regulation of skeletal muscle cell proliferation [GO:0014857]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal muscle fiber development [GO:0048741]; striated muscle cell differentiation [GO:0051146] GO:0000978; GO:0000981; GO:0002074; GO:0005634; GO:0005667; GO:0005737; GO:0006357; GO:0006915; GO:0014857; GO:0021984; GO:0043282; GO:0048741; GO:0048839; GO:0048935; GO:0051146 19493 XM_044315244.1 0 32 0 0 0 NA NA NA NA NA NA 19494 XM_044321435.1 0 23 7 0 2 NA NA NA NA NA NA 19495 XM_029349967.2 656 458 506 726 675 B2RY50 1.6e-140 Outer dynein arm-docking complex subunit 2 (Armadillo repeat-containing protein 4) Mus musculus (Mouse) cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; outer dynein arm assembly [GO:0036158]; regulation of cilium beat frequency [GO:0003356]; ventricular system development [GO:0021591] GO:0003341; GO:0003356; GO:0005930; GO:0007368; GO:0007507; GO:0021591; GO:0036158; GO:0097546 19496 XM_044317565.1 53 8 31 37 9 NA NA NA NA NA NA 19497 XM_044320714.1 0 0 0 1 10 NA NA NA NA NA NA 19498 XM_029329776.2 0 0 0 81 86 P79134 1.03e-72 Annexin A6 (Annexin VI) (Annexin-6) Bos taurus (Bovine) apoptotic signaling pathway [GO:0097190]; biomineral tissue development [GO:0031214]; calcium ion import [GO:0070509]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; growth plate cartilage chondrocyte differentiation [GO:0003418]; mitochondrial calcium ion homeostasis [GO:0051560]; negative regulation of sequestering of calcium ion [GO:0051283]; neural crest cell migration [GO:0001755]; plasma membrane repair [GO:0001778]; regulation of muscle contraction [GO:0006937] GO:0001725; GO:0001755; GO:0001778; GO:0001786; GO:0003418; GO:0005262; GO:0005509; GO:0005525; GO:0005544; GO:0005737; GO:0005886; GO:0005925; GO:0006816; GO:0006937; GO:0008201; GO:0015276; GO:0015485; GO:0016020; GO:0019899; GO:0030061; GO:0031214; GO:0031982; GO:0035374; GO:0038024; GO:0042470; GO:0042584; GO:0048306; GO:0048471; GO:0051015; GO:0051283; GO:0051560; GO:0070509; GO:0070588; GO:0097190 19499 XM_029329776.2 0 0 0 81 86 P79134 2.3e-59 Annexin A6 (Annexin VI) (Annexin-6) Bos taurus (Bovine) apoptotic signaling pathway [GO:0097190]; biomineral tissue development [GO:0031214]; calcium ion import [GO:0070509]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; growth plate cartilage chondrocyte differentiation [GO:0003418]; mitochondrial calcium ion homeostasis [GO:0051560]; negative regulation of sequestering of calcium ion [GO:0051283]; neural crest cell migration [GO:0001755]; plasma membrane repair [GO:0001778]; regulation of muscle contraction [GO:0006937] GO:0001725; GO:0001755; GO:0001778; GO:0001786; GO:0003418; GO:0005262; GO:0005509; GO:0005525; GO:0005544; GO:0005737; GO:0005886; GO:0005925; GO:0006816; GO:0006937; GO:0008201; GO:0015276; GO:0015485; GO:0016020; GO:0019899; GO:0030061; GO:0031214; GO:0031982; GO:0035374; GO:0038024; GO:0042470; GO:0042584; GO:0048306; GO:0048471; GO:0051015; GO:0051283; GO:0051560; GO:0070509; GO:0070588; GO:0097190 19500 XM_029329776.2 0 0 0 81 86 P79134 3.03e-38 Annexin A6 (Annexin VI) (Annexin-6) Bos taurus (Bovine) apoptotic signaling pathway [GO:0097190]; biomineral tissue development [GO:0031214]; calcium ion import [GO:0070509]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; growth plate cartilage chondrocyte differentiation [GO:0003418]; mitochondrial calcium ion homeostasis [GO:0051560]; negative regulation of sequestering of calcium ion [GO:0051283]; neural crest cell migration [GO:0001755]; plasma membrane repair [GO:0001778]; regulation of muscle contraction [GO:0006937] GO:0001725; GO:0001755; GO:0001778; GO:0001786; GO:0003418; GO:0005262; GO:0005509; GO:0005525; GO:0005544; GO:0005737; GO:0005886; GO:0005925; GO:0006816; GO:0006937; GO:0008201; GO:0015276; GO:0015485; GO:0016020; GO:0019899; GO:0030061; GO:0031214; GO:0031982; GO:0035374; GO:0038024; GO:0042470; GO:0042584; GO:0048306; GO:0048471; GO:0051015; GO:0051283; GO:0051560; GO:0070509; GO:0070588; GO:0097190 19501 XM_029329776.2 0 0 0 81 86 P79134 1.78e-34 Annexin A6 (Annexin VI) (Annexin-6) Bos taurus (Bovine) apoptotic signaling pathway [GO:0097190]; biomineral tissue development [GO:0031214]; calcium ion import [GO:0070509]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; growth plate cartilage chondrocyte differentiation [GO:0003418]; mitochondrial calcium ion homeostasis [GO:0051560]; negative regulation of sequestering of calcium ion [GO:0051283]; neural crest cell migration [GO:0001755]; plasma membrane repair [GO:0001778]; regulation of muscle contraction [GO:0006937] GO:0001725; GO:0001755; GO:0001778; GO:0001786; GO:0003418; GO:0005262; GO:0005509; GO:0005525; GO:0005544; GO:0005737; GO:0005886; GO:0005925; GO:0006816; GO:0006937; GO:0008201; GO:0015276; GO:0015485; GO:0016020; GO:0019899; GO:0030061; GO:0031214; GO:0031982; GO:0035374; GO:0038024; GO:0042470; GO:0042584; GO:0048306; GO:0048471; GO:0051015; GO:0051283; GO:0051560; GO:0070509; GO:0070588; GO:0097190 19502 XM_044312333.1 3175 3525 2305 2736 2593 NA NA NA NA NA NA 19503 XM_044312986.1 556 171 366 824 666 B7ZCC9 1e-47 Adhesion G-protein coupled receptor G4 (G-protein coupled receptor 112) Mus musculus (Mouse) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; neurogenesis [GO:0022008] GO:0004930; GO:0005886; GO:0007166; GO:0007189; GO:0022008 19504 XM_044328878.1 0 0 0 0 8 NA NA NA NA NA NA 19505 XM_029354578.2 2764 2769 1564 2808 2674 A2AGT5 0 Cytoskeleton-associated protein 5 Mus musculus (Mouse) cell division [GO:0051301]; central nervous system myelin formation [GO:0032289]; centrosome cycle [GO:0007098]; centrosome duplication [GO:0051298]; cytoplasmic translation [GO:0002181]; dendritic spine maintenance [GO:0097062]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; excitatory postsynaptic potential [GO:0060079]; habituation [GO:0046959]; locomotory behavior [GO:0007626]; long-term synaptic potentiation [GO:0060291]; microtubule polymerization [GO:0046785]; mitotic spindle organization [GO:0007052]; mRNA localization resulting in post-transcriptional regulation of gene expression [GO:0010609]; positive regulation of endocytosis [GO:0045807]; positive regulation of microtubule nucleation [GO:0090063]; ribonucleoprotein complex assembly [GO:0022618]; RNA transport [GO:0050658]; spindle organization [GO:0007051]; visual learning [GO:0008542] GO:0000776; GO:0000922; GO:0002181; GO:0005730; GO:0005737; GO:0005813; GO:0005886; GO:0007051; GO:0007052; GO:0007098; GO:0007626; GO:0008017; GO:0008542; GO:0010609; GO:0022618; GO:0030425; GO:0030951; GO:0032289; GO:0032991; GO:0035371; GO:0043021; GO:0043204; GO:0045807; GO:0046785; GO:0046959; GO:0050658; GO:0051010; GO:0051298; GO:0051301; GO:0060079; GO:0060291; GO:0061863; GO:0071598; GO:0090063; GO:0097062; GO:0098794 19506 XM_029354578.2 2764 2769 1564 2808 2674 A2AGT5 5.59e-156 Cytoskeleton-associated protein 5 Mus musculus (Mouse) cell division [GO:0051301]; central nervous system myelin formation [GO:0032289]; centrosome cycle [GO:0007098]; centrosome duplication [GO:0051298]; cytoplasmic translation [GO:0002181]; dendritic spine maintenance [GO:0097062]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; excitatory postsynaptic potential [GO:0060079]; habituation [GO:0046959]; locomotory behavior [GO:0007626]; long-term synaptic potentiation [GO:0060291]; microtubule polymerization [GO:0046785]; mitotic spindle organization [GO:0007052]; mRNA localization resulting in post-transcriptional regulation of gene expression [GO:0010609]; positive regulation of endocytosis [GO:0045807]; positive regulation of microtubule nucleation [GO:0090063]; ribonucleoprotein complex assembly [GO:0022618]; RNA transport [GO:0050658]; spindle organization [GO:0007051]; visual learning [GO:0008542] GO:0000776; GO:0000922; GO:0002181; GO:0005730; GO:0005737; GO:0005813; GO:0005886; GO:0007051; GO:0007052; GO:0007098; GO:0007626; GO:0008017; GO:0008542; GO:0010609; GO:0022618; GO:0030425; GO:0030951; GO:0032289; GO:0032991; GO:0035371; GO:0043021; GO:0043204; GO:0045807; GO:0046785; GO:0046959; GO:0050658; GO:0051010; GO:0051298; GO:0051301; GO:0060079; GO:0060291; GO:0061863; GO:0071598; GO:0090063; GO:0097062; GO:0098794 19507 XM_029354578.2 2764 2769 1564 2808 2674 A2AGT5 7.54e-133 Cytoskeleton-associated protein 5 Mus musculus (Mouse) cell division [GO:0051301]; central nervous system myelin formation [GO:0032289]; centrosome cycle [GO:0007098]; centrosome duplication [GO:0051298]; cytoplasmic translation [GO:0002181]; dendritic spine maintenance [GO:0097062]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; excitatory postsynaptic potential [GO:0060079]; habituation [GO:0046959]; locomotory behavior [GO:0007626]; long-term synaptic potentiation [GO:0060291]; microtubule polymerization [GO:0046785]; mitotic spindle organization [GO:0007052]; mRNA localization resulting in post-transcriptional regulation of gene expression [GO:0010609]; positive regulation of endocytosis [GO:0045807]; positive regulation of microtubule nucleation [GO:0090063]; ribonucleoprotein complex assembly [GO:0022618]; RNA transport [GO:0050658]; spindle organization [GO:0007051]; visual learning [GO:0008542] GO:0000776; GO:0000922; GO:0002181; GO:0005730; GO:0005737; GO:0005813; GO:0005886; GO:0007051; GO:0007052; GO:0007098; GO:0007626; GO:0008017; GO:0008542; GO:0010609; GO:0022618; GO:0030425; GO:0030951; GO:0032289; GO:0032991; GO:0035371; GO:0043021; GO:0043204; GO:0045807; GO:0046785; GO:0046959; GO:0050658; GO:0051010; GO:0051298; GO:0051301; GO:0060079; GO:0060291; GO:0061863; GO:0071598; GO:0090063; GO:0097062; GO:0098794 19508 XM_044325743.1 10 5 0 0 0 Q2KIA4 3.5e-86 Stearoyl-CoA desaturase 5 (EC 1.14.19.1) (Acyl-CoA-desaturase 4) (Stearoyl-CoA 9-desaturase) Bos taurus (Bovine) monounsaturated fatty acid biosynthetic process [GO:1903966]; unsaturated fatty acid biosynthetic process [GO:0006636] GO:0004768; GO:0005506; GO:0005789; GO:0006636; GO:0016491; GO:1903966 19509 XM_029328871.2 907 123 304 560 251 Q28DB0 2.61e-159 Tetratricopeptide repeat protein 39B (TPR repeat protein 39B) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) lipid metabolic process [GO:0006629] GO:0006629 19510 XM_029344741.2 62 182 0 114 91 NA NA NA NA NA NA 19511 XR_006397330.1 578 546 154 293 405 NA NA NA NA NA NA 19512 XM_044319001.1 0 66 0 0 0 Q9BXB4 0 Oxysterol-binding protein-related protein 11 (ORP-11) (OSBP-related protein 11) Homo sapiens (Human) fat cell differentiation [GO:0045444]; positive regulation of sequestering of triglyceride [GO:0010890] GO:0005654; GO:0005794; GO:0005829; GO:0010890; GO:0015248; GO:0016020; GO:0031902; GO:0032934; GO:0043231; GO:0045444 19513 XR_006396638.1 116 73 0 187 183 NA NA NA NA NA NA 19514 XM_044325784.1 198 79 75 60 70 P0C152 4.65e-179 Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67) Rattus norvegicus (Rat) branching morphogenesis of an epithelial tube [GO:0048754]; cilium assembly [GO:0060271]; determination of left/right symmetry [GO:0007368]; head development [GO:0060322]; heart development [GO:0007507]; kidney development [GO:0001822]; negative regulation of centrosome duplication [GO:0010826]; photoreceptor cell outer segment organization [GO:0035845]; positive regulation of ERAD pathway [GO:1904294]; positive regulation of non-motile cilium assembly [GO:1902857]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0001822; GO:0005789; GO:0005813; GO:0005886; GO:0007368; GO:0007507; GO:0010826; GO:0030433; GO:0030659; GO:0031005; GO:0035845; GO:0035869; GO:0036038; GO:0048754; GO:0051082; GO:0051787; GO:0060170; GO:0060271; GO:0060322; GO:1902857; GO:1904294 19515 XM_044315581.1 177 146 47 72 229 Q96PB1 9.16e-178 N-acetylneuraminate 9-O-acetyltransferase (EC 2.3.1.45) (CAS1 domain-containing protein 1) (Sialate O-acetyltransferase) (SOAT) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975] GO:0000139; GO:0005975; GO:0047186 19516 XR_003823949.2 3 0 0 6 9 NA NA NA NA NA NA 19517 XR_006394632.1 160 112 99 104 109 NA NA NA NA NA NA 19518 XM_044309782.1 22 0 14 10 9 P47990 6.59e-161 Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase) (XOR)] Gallus gallus (Chicken) urate biosynthetic process [GO:0034418]; xanthine catabolic process [GO:0009115] GO:0004854; GO:0004855; GO:0005506; GO:0005615; GO:0005777; GO:0005829; GO:0009115; GO:0016491; GO:0030151; GO:0034418; GO:0043546; GO:0050660; GO:0051537; GO:0070674; GO:0071949 19519 XM_029331145.2 14 0 22 10 29 NA NA NA NA NA NA 19520 XM_029334706.2 946 467 570 734 546 P53791 0 Sodium/glucose cotransporter 1 (Na(+)/glucose cotransporter 1) (High affinity sodium-glucose cotransporter) (Solute carrier family 5 member 1) Ovis aries (Sheep) glucose import across plasma membrane [GO:0098708]; intestinal D-glucose absorption [GO:0001951]; renal glucose absorption [GO:0035623]; response to inorganic substance [GO:0010035]; sodium ion import across plasma membrane [GO:0098719]; transepithelial water transport [GO:0035377]; transport across blood-brain barrier [GO:0150104] GO:0001951; GO:0005372; GO:0005412; GO:0005769; GO:0010035; GO:0015151; GO:0015371; GO:0016324; GO:0035377; GO:0035623; GO:0048471; GO:0055056; GO:0098708; GO:0098719; GO:0150104 19521 XR_006397008.1 25 60 32 83 55 NA NA NA NA NA NA 19522 XM_044312069.1 1063 7302 150 122 5933 NA NA NA NA NA NA 19523 XM_044329332.1 2155 1863 1225 2480 2423 Q6ZMW3 0 Echinoderm microtubule-associated protein-like 6 (EMAP-6) (Echinoderm microtubule-associated protein-like 5-like) Homo sapiens (Human) NA GO:0005737; GO:0005874; GO:0008017 19524 XM_044329332.1 2155 1863 1225 2480 2423 Q6ZMW3 6.82e-138 Echinoderm microtubule-associated protein-like 6 (EMAP-6) (Echinoderm microtubule-associated protein-like 5-like) Homo sapiens (Human) NA GO:0005737; GO:0005874; GO:0008017 19525 XR_006393845.1 0 4 6 0 20 NA NA NA NA NA NA 19526 XM_029332075.2 218 180 89 181 285 Q9NRG9 1.64e-139 Aladin (Adracalin) Homo sapiens (Human) fertilization [GO:0009566]; learning [GO:0007612]; microtubule bundle formation [GO:0001578]; mitotic spindle assembly [GO:0090307]; mRNA transport [GO:0051028]; nucleocytoplasmic transport [GO:0006913]; protein transport [GO:0015031]; regulation of nucleocytoplasmic transport [GO:0046822] GO:0000922; GO:0001578; GO:0005634; GO:0005635; GO:0005643; GO:0005654; GO:0005813; GO:0005829; GO:0006913; GO:0007612; GO:0009566; GO:0015031; GO:0016020; GO:0031965; GO:0046822; GO:0051028; GO:0072686; GO:0090307 19527 XM_044308969.1 86 17 36 32 65 NA NA NA NA NA NA 19528 XM_029327866.2 18 5 4 0 16 NA NA NA NA NA NA 19529 XM_044313968.1 33 15 23 27 66 NA NA NA NA NA NA 19530 XR_006392472.1 628 236 401 242 292 NA NA NA NA NA NA 19531 XM_029356466.2 23 4 30 5 258 B3EX02 0 MAM and fibronectin type III domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 19532 XM_029356466.2 23 4 30 5 258 B3EX02 1.84e-23 MAM and fibronectin type III domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 19533 XM_044310162.1 6 1 0 3 0 Q96AY4 1.54e-62 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19534 XM_044310162.1 6 1 0 3 0 Q96AY4 2.05e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19535 XM_044310162.1 6 1 0 3 0 Q96AY4 2.26e-57 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19536 XM_044310162.1 6 1 0 3 0 Q96AY4 6.67e-56 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19537 XM_044310162.1 6 1 0 3 0 Q96AY4 1.07e-54 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19538 XM_044310162.1 6 1 0 3 0 Q96AY4 4.95e-49 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19539 XM_044310162.1 6 1 0 3 0 Q96AY4 7.84e-49 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19540 XM_044310162.1 6 1 0 3 0 Q96AY4 3.14e-46 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19541 XM_044310162.1 6 1 0 3 0 Q96AY4 4.04e-46 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19542 XM_044310162.1 6 1 0 3 0 Q96AY4 2.58e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19543 XM_044310162.1 6 1 0 3 0 Q96AY4 1.59e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19544 XM_029328339.2 1 0 0 6 5 NA NA NA NA NA NA 19545 XM_029339349.2 1199 1348 669 1029 833 O02691 1.81e-112 3-hydroxyacyl-CoA dehydrogenase type-2 (EC 1.1.1.35) (17-beta-estradiol 17-dehydrogenase) (EC 1.1.1.62) (2-methyl-3-hydroxybutyryl-CoA dehydrogenase) (MHBD) (3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))) (EC 1.1.1.239) (3-hydroxy-2-methylbutyryl-CoA dehydrogenase) (EC 1.1.1.178) (3-hydroxyacyl-CoA dehydrogenase type II) (3alpha(or 20beta)-hydroxysteroid dehydrogenase) (EC 1.1.1.53) (7-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.159) (Endoplasmic reticulum-associated amyloid beta-peptide-binding protein) (Mitochondrial ribonuclease P protein 2) (Mitochondrial RNase P protein 2) (Short chain dehydrogenase/reductase family 5C member 1) (Short-chain type dehydrogenase/reductase XH98G2) (Type II HADH) Bos taurus (Bovine) androgen metabolic process [GO:0008209]; bile acid biosynthetic process [GO:0006699]; brexanolone metabolic process [GO:0062173]; C21-steroid hormone metabolic process [GO:0008207]; estrogen metabolic process [GO:0008210]; fatty acid beta-oxidation [GO:0006635]; fatty acid metabolic process [GO:0006631]; isoleucine catabolic process [GO:0006550]; mitochondrial tRNA 3'-end processing [GO:1990180]; mitochondrial tRNA 5'-end processing [GO:0097745]; mitochondrial tRNA methylation [GO:0070901]; mitochondrion organization [GO:0007005]; protein homotetramerization [GO:0051289] GO:0000049; GO:0003857; GO:0004303; GO:0005739; GO:0006550; GO:0006631; GO:0006635; GO:0006699; GO:0007005; GO:0008207; GO:0008209; GO:0008210; GO:0008709; GO:0030283; GO:0030678; GO:0042645; GO:0043527; GO:0044594; GO:0047015; GO:0047035; GO:0047044; GO:0051289; GO:0062173; GO:0070901; GO:0097745; GO:0106281; GO:0106282; GO:0106283; GO:1990180 19546 XM_029346675.2 305 268 321 639 418 NA NA NA NA NA NA 19547 XM_029356746.2 97 226 0 280 0 Q9Y4P3 8.66e-119 Transducin beta-like protein 2 (WS beta-transducin repeats protein) (WS-betaTRP) (Williams-Beuren syndrome chromosomal region 13 protein) Homo sapiens (Human) cellular response to glucose starvation [GO:0042149]; cellular response to hypoxia [GO:0071456]; endoplasmic reticulum unfolded protein response [GO:0030968] GO:0003723; GO:0005783; GO:0005789; GO:0019901; GO:0030968; GO:0031369; GO:0042149; GO:0051219; GO:0071456 19548 XR_006393302.1 45 23 0 0 39 Q5ZI69 3.27e-33 39S ribosomal protein L37, mitochondrial (L37mt) (MRP-L37) Gallus gallus (Chicken) translation [GO:0006412] GO:0003735; GO:0005739; GO:0005743; GO:0005762; GO:0006412 19549 XM_029333677.2 50 44 36 54 47 NA NA NA NA NA NA 19550 XM_029355367.2 22 0 8 37 171 NA NA NA NA NA NA 19551 XR_006392320.1 318 267 419 75 195 NA NA NA NA NA NA 19552 XM_029323624.2 285 208 291 208 399 NA NA NA NA NA NA 19553 XM_029352245.2 2832 2923 1656 2809 2023 Q61469 1.01e-43 Phospholipid phosphatase 1 (EC 3.1.3.-) (EC 3.1.3.106) (EC 3.1.3.4) (EC 3.6.1.75) (35 kDa PAP) (mPAP) (Hydrogen peroxide-inducible protein 53) (Hic53) (Lipid phosphate phosphohydrolase 1) (PAP2-alpha) (Phosphatidate phosphohydrolase type 2a) (Phosphatidic acid phosphatase 2a) (PAP-2a) (PAP2a) Mus musculus (Mouse) ceramide metabolic process [GO:0006672]; diacylglycerol biosynthetic process [GO:0006651]; phospholipid dephosphorylation [GO:0046839]; phospholipid metabolic process [GO:0006644]; signal transduction [GO:0007165]; sphingosine metabolic process [GO:0006670] GO:0000810; GO:0005886; GO:0005901; GO:0006644; GO:0006651; GO:0006670; GO:0006672; GO:0007165; GO:0008195; GO:0016020; GO:0016324; GO:0042392; GO:0042577; GO:0045121; GO:0046839; GO:0106235 19554 XM_044321654.1 130 0 0 36 0 Q1LZC5 4.32e-39 Ankyrin repeat domain-containing protein 54 Bos taurus (Bovine) nucleocytoplasmic transport [GO:0006913]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of intracellular signal transduction [GO:1902531]; regulation of protein kinase activity [GO:0045859] GO:0005634; GO:0005737; GO:0006913; GO:0019887; GO:0030496; GO:0044877; GO:0045648; GO:0045859; GO:1902531 19555 XM_029338651.2 989 841 486 796 734 P83877 3.02e-93 Thioredoxin-like protein 4A (DIM1 protein homolog) (Spliceosomal U5 snRNP-specific 15 kDa protein) (Thioredoxin-like U5 snRNP protein U5-15kD) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0005634; GO:0005654; GO:0005681; GO:0005682; GO:0005737; GO:0005829; GO:0007049; GO:0031965; GO:0046540; GO:0051301; GO:0071005 19556 XM_029331041.2 1716 3595 1354 1082 3551 Q6Q2B2 6.07e-60 Muscleblind-like protein 2a (Tmbnl2a) Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0003723; GO:0005634; GO:0005737; GO:0006397; GO:0008380; GO:0046872 19557 XM_029348281.2 61 105 73 108 61 P42325 3.38e-85 Neurocalcin homolog (DrosNCa) Drosophila melanogaster (Fruit fly) negative regulation of neuronal signal transduction [GO:1902848]; positive regulation of circadian sleep/wake cycle, sleep [GO:0045938] GO:0005509; GO:0045938; GO:1902848 19558 XM_029335972.2 1699 1397 759 1602 461 Q502L2 6.81e-78 Serine/threonine-protein phosphatase PGAM5, mitochondrial (EC 3.1.3.16) (Phosphoglycerate mutase family member 5) Danio rerio (Zebrafish) (Brachydanio rerio) peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of mitochondrial fission [GO:0090141]; programmed cell death [GO:0012501] GO:0004722; GO:0005739; GO:0005741; GO:0012501; GO:0017018; GO:0035970; GO:0090141 19559 XM_044307143.1 38 2 10 14 0 NA NA NA NA NA NA 19560 XM_044328829.1 0 0 14 0 0 NA NA NA NA NA NA 19561 XM_044326455.1 41 2 33 50 37 NA NA NA NA NA NA 19562 XM_029337828.2 4306 6023 3010 4022 5140 P62255 3.83e-78 Ubiquitin-conjugating enzyme E2 G1 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme G1) (E217K) (UBC7) (Ubiquitin carrier protein G1) (Ubiquitin-protein ligase G1) [Cleaved into: Ubiquitin-conjugating enzyme E2 G1, N-terminally processed] Rattus norvegicus (Rat) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein catabolic process [GO:0030163]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000209; GO:0004842; GO:0005524; GO:0006511; GO:0016567; GO:0030163; GO:0031625; GO:0043161; GO:0061631; GO:0070534; GO:0070936 19563 XM_044313482.1 102 4 0 0 3 NA NA NA NA NA NA 19564 XM_029340312.2 2260 1558 1566 2827 2817 B8UU59 0 Polycystic kidney disease 1-related protein Acropora millepora (Staghorn coral) (Heteropora millepora) kidney development [GO:0001822] GO:0001822; GO:0005929; GO:0016020 19565 XM_044306747.1 78 89 4 127 130 NA NA NA NA NA NA 19566 XR_003826730.2 211 134 128 107 199 NA NA NA NA NA NA 19567 XM_044326654.1 15 21 12 30 52 NA NA NA NA NA NA 19568 XR_006397341.1 37 46 2 12 21 NA NA NA NA NA NA 19569 XM_044314876.1 67 45 42 54 157 Q96AY4 2.49e-91 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19570 XM_044314876.1 67 45 42 54 157 Q96AY4 1.58e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19571 XM_044314876.1 67 45 42 54 157 Q96AY4 9.27e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19572 XM_044314876.1 67 45 42 54 157 Q96AY4 1.59e-84 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19573 XM_044314876.1 67 45 42 54 157 Q96AY4 5.91e-51 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19574 XM_044314876.1 67 45 42 54 157 Q96AY4 2.77e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19575 XM_044312523.1 159 94 49 159 182 O18638 7.27e-52 Out at first protein Drosophila virilis (Fruit fly) NA NA 19576 XM_029357867.2 628 471 809 628 642 Q80V03 1.27e-179 Uncharacterized aarF domain-containing protein kinase 5 (EC 2.7.11.-) Mus musculus (Mouse) phosphorylation [GO:0016310] GO:0004674; GO:0005739; GO:0016020; GO:0016310 19577 XM_044307886.1 600 911 476 533 299 Q6DIP8 1.91e-95 Cotranscriptional regulator FAM172A homolog (Protein FAM172A) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0005634; GO:0005737; GO:0006397; GO:0008380 19578 XR_006392917.1 41 2 25 5 151 NA NA NA NA NA NA 19579 XM_029341357.2 0 13 50 46 164 O16374 3.99e-28 Beta-1,4-galactosyltransferase galt-1 (EC 2.4.1.-) Caenorhabditis elegans N-glycan processing [GO:0006491]; protein galactosylation [GO:0042125] GO:0003831; GO:0006491; GO:0032580; GO:0035250; GO:0042125; GO:0043229; GO:0046872 19580 XM_029342781.2 9 14 2 10 33 NA NA NA NA NA NA 19581 XM_029341521.2 6 9 0 6 3 P25931 8.22e-25 RYamide receptor (Neuropeptide Y-like receptor) (NPY-R) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218] GO:0001653; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0016020 19582 XM_044316192.1 29 0 0 0 0 NA NA NA NA NA NA 19583 XM_044314947.1 43 19 87 168 101 NA NA NA NA NA NA 19584 XM_029334814.2 102 32 21 87 54 NA NA NA NA NA NA 19585 XM_044318547.1 94 52 101 135 285 NA NA NA NA NA NA 19586 XM_044318626.1 49 33 1 33 9 NA NA NA NA NA NA 19587 XR_006392772.1 14 10 4 24 17 NA NA NA NA NA NA 19588 XM_044312630.1 5 29 24 13 29 NA NA NA NA NA NA 19589 XM_029327225.2 1533 796 831 1242 1307 Q5FWS6 1.99e-82 Kazrin Rattus norvegicus (Rat) keratinization [GO:0031424] GO:0001533; GO:0005829; GO:0005856; GO:0016607; GO:0030057; GO:0031424 19590 XM_029327225.2 1533 796 831 1242 1307 Q5FWS6 2.73e-24 Kazrin Rattus norvegicus (Rat) keratinization [GO:0031424] GO:0001533; GO:0005829; GO:0005856; GO:0016607; GO:0030057; GO:0031424 19591 XM_029330195.2 764 533 597 879 429 Q40784 3.38e-56 Putative glucose-6-phosphate 1-epimerase (EC 5.1.3.15) (Putative D-hexose-6-phosphate mutarotase) (Putative apospory-associated protein C) Cenchrus ciliaris (Buffelgrass) (Pennisetum ciliare) carbohydrate metabolic process [GO:0005975] GO:0005975; GO:0030246; GO:0047938 19592 XM_029333794.2 137 37 64 114 241 Q9UGM3 3.53e-124 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 19593 XM_029333794.2 137 37 64 114 241 Q9UGM3 7.88e-121 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 19594 XM_029348811.2 14 3 0 0 4 Q8NCC3 6.17e-105 Phospholipase A2 group XV (1-O-acylceramide synthase) (ACS) (LCAT-like lysophospholipase) (LLPL) (EC 3.1.1.5) (Lysophospholipase 3) (Lysosomal phospholipase A and acyltransferase) (EC 2.3.1.-, EC 3.1.1.32, EC 3.1.1.4) (Lysosomal phospholipase A2) (LPLA2) Homo sapiens (Human) ceramide metabolic process [GO:0006672]; diacylglycerol biosynthetic process [GO:0006651]; fatty acid catabolic process [GO:0009062]; glycerophospholipid metabolic process [GO:0006650]; lipid metabolic process [GO:0006629]; phosphatidylcholine catabolic process [GO:0034638]; phosphatidylcholine metabolic process [GO:0046470]; phosphatidylethanolamine catabolic process [GO:0046338]; phosphatidylglycerol metabolic process [GO:0046471]; phosphatidylserine metabolic process [GO:0006658]; phospholipid metabolic process [GO:0006644] GO:0004622; GO:0005543; GO:0005576; GO:0005615; GO:0005654; GO:0005764; GO:0006629; GO:0006644; GO:0006650; GO:0006651; GO:0006658; GO:0006672; GO:0008270; GO:0008374; GO:0008970; GO:0009062; GO:0016020; GO:0016411; GO:0034638; GO:0043231; GO:0046338; GO:0046470; GO:0046471; GO:0047499; GO:0052739; GO:0052740; GO:0070062; GO:0102545 19595 XM_044321473.1 70 23 25 160 147 NA NA NA NA NA NA 19596 XR_003827459.2 47 27 36 62 31 NA NA NA NA NA NA 19597 XR_006396308.1 67 5 21 31 50 NA NA NA NA NA NA 19598 XR_006394990.1 0 31 114 55 98 NA NA NA NA NA NA 19599 XM_029342139.2 118 0 20 0 40 NA NA NA NA NA NA 19600 XR_006397863.1 226 2 144 166 433 NA NA NA NA NA NA 19601 XM_044320433.1 9 0 0 1 0 Q09575 4.16e-43 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 19602 XM_029358446.2 1725 901 498 898 403 NA NA NA NA NA NA 19603 XM_044312459.1 0 265 0 3 654 Q9NZM1 0 Myoferlin (Fer-1-like protein 3) Homo sapiens (Human) blood circulation [GO:0008015]; membrane fusion [GO:0061025]; muscle contraction [GO:0006936]; plasma membrane organization [GO:0007009]; plasma membrane repair [GO:0001778]; T-tubule organization [GO:0033292] GO:0001778; GO:0005543; GO:0005635; GO:0005886; GO:0005901; GO:0006936; GO:0007009; GO:0008015; GO:0030659; GO:0031410; GO:0031965; GO:0033292; GO:0043231; GO:0046872; GO:0061025; GO:0070062 19604 XM_029354134.2 92 65 19 28 0 Q6DHN0 1.08e-30 Transmembrane protein 53 Danio rerio (Zebrafish) (Brachydanio rerio) negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of ossification [GO:0030279]; negative regulation of osteoblast differentiation [GO:0045668]; regulation of nucleocytoplasmic transport [GO:0046822] GO:0005640; GO:0030279; GO:0030514; GO:0031965; GO:0045668; GO:0046822 19605 XM_029343442.2 2716 2370 2123 2769 2693 Q6DEJ5 1.15e-125 Alanyl-tRNA editing protein Aarsd1 (Alanyl-tRNA synthetase domain-containing protein 1) Danio rerio (Zebrafish) (Brachydanio rerio) regulation of translational fidelity [GO:0006450]; translation [GO:0006412]; tRNA aminoacylation [GO:0043039] GO:0002196; GO:0004812; GO:0005524; GO:0005737; GO:0006412; GO:0006450; GO:0043039; GO:0046872 19606 XM_044317411.1 170 83 25 112 40 NA NA NA NA NA NA 19607 XM_044324520.1 30 338 245 87 188 NA NA NA NA NA NA 19608 XM_029357459.2 210 120 137 161 84 P15388 1.47e-89 Potassium voltage-gated channel subfamily C member 1 (NGK2) (Voltage-gated potassium channel subunit Kv3.1) (Voltage-gated potassium channel subunit Kv4) Mus musculus (Mouse) cellular response to xenobiotic stimulus [GO:0071466]; cerebellum development [GO:0021549]; corpus callosum development [GO:0022038]; globus pallidus development [GO:0021759]; optic nerve development [GO:0021554]; positive regulation of ion transmembrane transport [GO:0034767]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of voltage-gated potassium channel activity [GO:1903818]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; protein tetramerization [GO:0051262]; regulation of ion transmembrane transport [GO:0034765]; regulation of potassium ion transmembrane transport [GO:1901379]; response to amine [GO:0014075]; response to auditory stimulus [GO:0010996]; response to fibroblast growth factor [GO:0071774]; response to light intensity [GO:0009642]; response to nerve growth factor [GO:1990089]; response to potassium ion [GO:0035864]; response to toxic substance [GO:0009636] GO:0005249; GO:0005251; GO:0008076; GO:0009636; GO:0009642; GO:0009986; GO:0010996; GO:0014075; GO:0016020; GO:0019894; GO:0021549; GO:0021554; GO:0021759; GO:0022038; GO:0030424; GO:0030425; GO:0030673; GO:0032589; GO:0032590; GO:0032809; GO:0034765; GO:0034767; GO:0035864; GO:0042734; GO:0043025; GO:0044305; GO:0044325; GO:0045211; GO:0051260; GO:0051262; GO:0071466; GO:0071774; GO:0071805; GO:0099508; GO:1901379; GO:1901381; GO:1903818; GO:1990089 19609 XM_044324515.1 3446 1798 1570 2934 3392 Q5R7X2 0 U2 snRNP-associated SURP motif-containing protein (140 kDa Ser/Arg-rich domain protein) (U2-associated protein SR140) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) RNA processing [GO:0006396] GO:0003723; GO:0005634; GO:0006396 19610 XM_044312332.1 0 9 0 0 0 NA NA NA NA NA NA 19611 XM_044307392.1 8 7 101 4 41 Q86V86 1.5e-53 Serine/threonine-protein kinase pim-3 (EC 2.7.11.1) Homo sapiens (Human) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; negative regulation of apoptotic process [GO:0043066]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of mitotic cell cycle [GO:0007346] GO:0004674; GO:0005524; GO:0005737; GO:0005829; GO:0006468; GO:0006915; GO:0007049; GO:0007346; GO:0043066; GO:0046777; GO:0061179; GO:0106310 19612 XM_029352049.2 75 27 31 51 39 NA NA NA NA NA NA 19613 XM_044327674.1 440 307 237 368 371 Q9JI78 1.2e-179 Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase (PNGase) (mPNGase) (EC 3.5.1.52) (N-glycanase 1) (Peptide:N-glycanase) Mus musculus (Mouse) ER-associated misfolded protein catabolic process [GO:0071712]; glycoprotein catabolic process [GO:0006516]; protein deglycosylation [GO:0006517]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515] GO:0000224; GO:0005634; GO:0005737; GO:0005829; GO:0006515; GO:0006516; GO:0006517; GO:0046872; GO:0062023; GO:0071712 19614 XM_044308615.1 0 26 24 0 2 NA NA NA NA NA NA 19615 XM_044307861.1 0 6 0 2 0 NA NA NA NA NA NA 19616 XM_029329859.2 423 0 4 6 410 P20072 4.02e-70 Annexin A7 (Annexin VII) (Annexin-7) (Synexin) Bos taurus (Bovine) NA GO:0005509; GO:0005544; GO:0005634; GO:0005737; GO:0042584 19617 XM_044312955.1 81 32 19 32 38 Q8K3Z0 2.6e-35 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 19618 XM_029348431.2 2885 3873 2064 3362 2460 NA NA NA NA NA NA 19619 XR_006393131.1 16 16485 77 18610 16 NA NA NA NA NA NA 19620 XM_044309166.1 118 45 49 98 129 NA NA NA NA NA NA 19621 XM_044307304.1 3194 3148 4764 5168 6738 Q3UFK8 1.41e-69 FERM domain-containing protein 8 (iRhom tail-associated protein) (iTAP) Mus musculus (Mouse) negative regulation of canonical Wnt signaling pathway [GO:0090090]; positive regulation of tumor necrosis factor production [GO:0032760]; protein localization to plasma membrane [GO:0072659] GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0032760; GO:0034451; GO:0072659; GO:0090090 19622 XM_029340688.2 592 409 398 343 494 Q2TBL4 2.89e-136 DNA-directed RNA polymerase III subunit RPC3 (RNA polymerase III subunit C3) (DNA-directed RNA polymerase III subunit C) Bos taurus (Bovine) defense response to virus [GO:0051607]; DNA-templated transcription [GO:0006351]; innate immune response [GO:0045087]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-beta production [GO:0032728] GO:0003697; GO:0005654; GO:0005666; GO:0006351; GO:0032728; GO:0045087; GO:0045089; GO:0051607 19623 XM_029328911.2 273 92 75 192 288 Q9NPF5 5.98e-133 DNA methyltransferase 1-associated protein 1 (DNMAP1) (DNMT1-associated protein 1) Homo sapiens (Human) chromatin remodeling [GO:0006338]; DNA methylation [GO:0006306]; DNA repair [GO:0006281]; histone acetylation [GO:0016573]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of protein import into nucleus [GO:0042307]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of DNA-templated transcription [GO:0006355]; regulation of double-strand break repair [GO:2000779]; response to ethanol [GO:0045471] GO:0000122; GO:0000786; GO:0000812; GO:0003714; GO:0005634; GO:0005654; GO:0005657; GO:0005737; GO:0005829; GO:0006281; GO:0006306; GO:0006338; GO:0006355; GO:0016573; GO:0035267; GO:0042307; GO:0042981; GO:0043967; GO:0043968; GO:0045471; GO:0045892; GO:0045893; GO:0051726; GO:0061629; GO:1905168; GO:2000779 19624 XM_044324866.1 0 0 0 0 18 Q6NS23 1.57e-128 tRNA (guanine(10)-N2)-methyltransferase homolog (EC 2.1.1.-) (tRNA guanosine-2'-O-methyltransferase TRM11 homolog) Xenopus laevis (African clawed frog) RNA methylation [GO:0001510]; tRNA processing [GO:0008033] GO:0000049; GO:0001510; GO:0008033; GO:0008168 19625 XM_044311313.1 38 211 23 394 1 NA NA NA NA NA NA 19626 XM_044320820.1 0 0 0 0 35 NA NA NA NA NA NA 19627 XM_029337747.2 935 1417 1073 1873 1618 Q69ZU8 6.07e-50 Ankyrin repeat domain-containing protein 6 (Diversin) Mus musculus (Mouse) negative regulation of canonical Wnt signaling pathway [GO:0090090]; positive regulation of JNK cascade [GO:0046330]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096] GO:0005634; GO:0005737; GO:0043231; GO:0046330; GO:0090090; GO:2000096 19628 XM_044311106.1 15 0 0 0 0 NA NA NA NA NA NA 19629 XR_006394343.1 29 17 14 88 119 NA NA NA NA NA NA 19630 XM_044317985.1 0 0 0 22 0 NA NA NA NA NA NA 19631 XM_044307530.1 0 23 0 0 9 NA NA NA NA NA NA 19632 XM_044317665.1 2069 641 32 141 800 NA NA NA NA NA NA 19633 XM_029336578.2 0 0 95 0 0 Q66KD6 1.72e-52 Probable phosphatase phospho2 (EC 3.1.3.-) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0016791; GO:0046872 19634 XM_029343325.2 0 9 22 8 41 Q6P9K9 2.79e-30 Neurexin-3 (Neurexin III-alpha) (Neurexin-3-alpha) Mus musculus (Mouse) adult behavior [GO:0030534]; cell adhesion [GO:0007155]; chemical synaptic transmission [GO:0007268]; learning [GO:0007612]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; neurotransmitter secretion [GO:0007269]; postsynaptic density assembly [GO:0097107]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; trans-synaptic signaling [GO:0099537]; vocalization behavior [GO:0071625] GO:0005246; GO:0007155; GO:0007268; GO:0007269; GO:0007416; GO:0007612; GO:0030534; GO:0032991; GO:0035176; GO:0042734; GO:0046872; GO:0071625; GO:0097107; GO:0098978; GO:0098982; GO:0099072; GO:0099171; GO:0099537; GO:0099645 19635 XM_029343325.2 0 9 22 8 41 Q6P9K9 2.56e-22 Neurexin-3 (Neurexin III-alpha) (Neurexin-3-alpha) Mus musculus (Mouse) adult behavior [GO:0030534]; cell adhesion [GO:0007155]; chemical synaptic transmission [GO:0007268]; learning [GO:0007612]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; neurotransmitter secretion [GO:0007269]; postsynaptic density assembly [GO:0097107]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; trans-synaptic signaling [GO:0099537]; vocalization behavior [GO:0071625] GO:0005246; GO:0007155; GO:0007268; GO:0007269; GO:0007416; GO:0007612; GO:0030534; GO:0032991; GO:0035176; GO:0042734; GO:0046872; GO:0071625; GO:0097107; GO:0098978; GO:0098982; GO:0099072; GO:0099171; GO:0099537; GO:0099645 19636 XR_006393144.1 10360 9652 8679 78 5048 NA NA NA NA NA NA 19637 XM_029335188.2 138 87 191 208 83 P12716 0 Actin, cytoplasmic (EC 3.6.4.-) [Cleaved into: Actin, cytoplasmic, intermediate form] Pisaster ochraceus (Ochre sea star) (Asterias ochracea) NA GO:0005524; GO:0005737; GO:0005856; GO:0016787 19638 XM_029344976.2 0 0 147 0 0 Q8NF64 1.42e-139 Zinc finger MIZ domain-containing protein 2 (PIAS-like protein Zimp7) Homo sapiens (Human) positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0005634; GO:0005654; GO:0005739; GO:0006357; GO:0008270; GO:0030374; GO:0043596; GO:0045944 19639 XM_044318922.1 7739 13170 5436 43604 31668 O54857 1.24e-109 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (EC 3.1.3.16) (EC 3.1.3.48) (EC 3.1.3.67) (Phosphatase and tensin homolog) Rattus norvegicus (Rat) adult behavior [GO:0030534]; aging [GO:0007568]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; B cell proliferation [GO:0042100]; brain morphogenesis [GO:0048854]; canonical Wnt signaling pathway [GO:0060070]; cardiac muscle tissue development [GO:0048738]; cell migration [GO:0016477]; cell motility [GO:0048870]; cell population proliferation [GO:0008283]; cellular response to decreased oxygen levels [GO:0036294]; cellular response to electrical stimulus [GO:0071257]; cellular response to ethanol [GO:0071361]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to leptin stimulus [GO:0044320]; cellular response to nerve growth factor stimulus [GO:1990090]; central nervous system development [GO:0007417]; central nervous system myelin maintenance [GO:0032286]; central nervous system neuron axonogenesis [GO:0021955]; dendritic spine morphogenesis [GO:0060997]; dentate gyrus development [GO:0021542]; dephosphorylation [GO:0016311]; endothelial cell migration [GO:0043542]; forebrain morphogenesis [GO:0048853]; heart development [GO:0007507]; inositol phosphate dephosphorylation [GO:0046855]; learning or memory [GO:0007611]; locomotor rhythm [GO:0045475]; locomotory behavior [GO:0007626]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; male mating behavior [GO:0060179]; maternal behavior [GO:0042711]; memory [GO:0007613]; multicellular organismal response to stress [GO:0033555]; myelination [GO:0042552]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axon regeneration [GO:0048681]; negative regulation of axonogenesis [GO:0050771]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell cycle G1/S phase transition [GO:1902807]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of cellular senescence [GO:2000773]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of defense response to bacterium [GO:1900425]; negative regulation of dendrite extension [GO:1903860]; negative regulation of dendritic spine morphogenesis [GO:0061002]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of keratinocyte migration [GO:0051548]; negative regulation of myelination [GO:0031642]; negative regulation of neuron projection development [GO:0010977]; negative regulation of organ growth [GO:0046621]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of phagocytosis [GO:0050765]; negative regulation of phagocytosis, engulfment [GO:0060101]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of ribosome biogenesis [GO:0090071]; negative regulation of signaling receptor activity [GO:2000272]; negative regulation of synaptic vesicle clustering [GO:2000808]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of vascular associated smooth muscle cell proliferation [GO:1904706]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; neuron projection development [GO:0031175]; neuron-neuron synaptic transmission [GO:0007270]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol dephosphorylation [GO:0046856]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of TRAIL-activated apoptotic signaling pathway [GO:1903984]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; postsynaptic density assembly [GO:0097107]; prepulse inhibition [GO:0060134]; presynaptic membrane assembly [GO:0097105]; prostate gland growth [GO:0060736]; protein dephosphorylation [GO:0006470]; protein kinase B signaling [GO:0043491]; protein stabilization [GO:0050821]; regulation of axon regeneration [GO:0048679]; regulation of B cell apoptotic process [GO:0002902]; regulation of cell cycle [GO:0051726]; regulation of cellular component size [GO:0032535]; regulation of cellular localization [GO:0060341]; regulation of macrophage apoptotic process [GO:2000109]; regulation of myeloid cell apoptotic process [GO:0033032]; regulation of neuron projection development [GO:0010975]; regulation of protein kinase B signaling [GO:0051896]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to activity [GO:0014823]; response to arsenic-containing substance [GO:0046685]; response to ATP [GO:0033198]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to glucose [GO:0009749]; response to inorganic substance [GO:0010035]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to xenobiotic stimulus [GO:0009410]; response to zinc ion [GO:0010043]; rhythmic synaptic transmission [GO:0060024]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; synapse maturation [GO:0060074]; T cell proliferation [GO:0042098] GO:0001525; GO:0001933; GO:0002902; GO:0004438; GO:0004721; GO:0004722; GO:0004725; GO:0005161; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0005886; GO:0006470; GO:0006915; GO:0007270; GO:0007416; GO:0007417; GO:0007507; GO:0007568; GO:0007584; GO:0007611; GO:0007613; GO:0007626; GO:0008138; GO:0008283; GO:0008284; GO:0008285; GO:0009410; GO:0009749; GO:0009898; GO:0010033; GO:0010035; GO:0010043; GO:0010628; GO:0010666; GO:0010719; GO:0010975; GO:0010977; GO:0010997; GO:0014065; GO:0014069; GO:0014070; GO:0014823; GO:0016311; GO:0016314; GO:0016324; GO:0016477; GO:0016605; GO:0016791; GO:0017018; GO:0019899; GO:0019901; GO:0021542; GO:0021955; GO:0030165; GO:0030336; GO:0030534; GO:0030889; GO:0031175; GO:0031642; GO:0031647; GO:0032228; GO:0032286; GO:0032355; GO:0032535; GO:0032869; GO:0033032; GO:0033137; GO:0033198; GO:0033555; GO:0035176; GO:0035255; GO:0035749; GO:0036294; GO:0042098; GO:0042100; GO:0042130; GO:0042552; GO:0042711; GO:0042802; GO:0042995; GO:0043005; GO:0043065; GO:0043066; GO:0043197; GO:0043220; GO:0043491; GO:0043542; GO:0044320; GO:0045211; GO:0045471; GO:0045475; GO:0045666; GO:0045736; GO:0045786; GO:0045792; GO:0046621; GO:0046685; GO:0046855; GO:0046856; GO:0048008; GO:0048679; GO:0048681; GO:0048738; GO:0048853; GO:0048854; GO:0048870; GO:0050680; GO:0050765; GO:0050771; GO:0050821; GO:0051091; GO:0051548; GO:0051717; GO:0051726; GO:0051800; GO:0051895; GO:0051896; GO:0051898; GO:0060024; GO:0060044; GO:0060070; GO:0060074; GO:0060101; GO:0060134; GO:0060179; GO:0060291; GO:0060292; GO:0060341; GO:0060736; GO:0060997; GO:0061002; GO:0070373; GO:0070374; GO:0071257; GO:0071361; GO:0071456; GO:0090071; GO:0090394; GO:0097105; GO:0097107; GO:0099524; GO:1900425; GO:1901017; GO:1902807; GO:1903690; GO:1903860; GO:1903984; GO:1904668; GO:1904706; GO:1990090; GO:1990314; GO:1990381; GO:1990782; GO:2000060; GO:2000109; GO:2000134; GO:2000272; GO:2000463; GO:2000773; GO:2000808; GO:2001235 19640 XM_044309326.1 9 0 0 76 2 NA NA NA NA NA NA 19641 XM_044321155.1 0 1 17 0 12 NA NA NA NA NA NA 19642 XM_029357503.2 32 804 2 115 0 P23824 2.69e-70 GATA-binding factor 2 (GATA-2) (Transcription factor NF-E1b) Gallus gallus (Chicken) cell fate commitment [GO:0045165]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of angiogenesis [GO:0045766]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000122; GO:0000978; GO:0000981; GO:0001223; GO:0005634; GO:0008270; GO:0045165; GO:0045766; GO:0045944; GO:1902895 19643 XR_006397129.1 98 53 48 102 20 NA NA NA NA NA NA 19644 XR_003827171.2 0 0 0 11 4 Q4KM95 1.97e-42 Leucine-rich repeat-containing protein 42 Rattus norvegicus (Rat) NA NA 19645 XM_044327561.1 0 10 157 47 10 Q9CUX1 2.56e-29 52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (THAP domain-containing protein 0) (THAP domain-containing protein 12) Mus musculus (Mouse) NA GO:0003677; GO:0005634; GO:0046872; GO:0046983 19646 XR_006392433.1 0 0 1 1 22 NA NA NA NA NA NA 19647 XM_044311259.1 60 0 23 0 107 NA NA NA NA NA NA 19648 XM_044317673.1 1925 1225 1277 2006 2475 Q5SPC5 0 Otoferlin (Fer-1-like protein 2) Danio rerio (Zebrafish) (Brachydanio rerio) neuromuscular process controlling balance [GO:0050885]; plasma membrane organization [GO:0007009]; response to auditory stimulus [GO:0010996]; sensory perception of sound [GO:0007605]; startle response [GO:0001964]; synaptic vesicle exocytosis [GO:0016079]; synaptic vesicle priming [GO:0016082] GO:0000139; GO:0001964; GO:0005509; GO:0005789; GO:0007009; GO:0007605; GO:0010996; GO:0016079; GO:0016082; GO:0016323; GO:0030672; GO:0035612; GO:0042995; GO:0048787; GO:0050885 19649 XM_044317673.1 1925 1225 1277 2006 2475 Q5SPC5 0 Otoferlin (Fer-1-like protein 2) Danio rerio (Zebrafish) (Brachydanio rerio) neuromuscular process controlling balance [GO:0050885]; plasma membrane organization [GO:0007009]; response to auditory stimulus [GO:0010996]; sensory perception of sound [GO:0007605]; startle response [GO:0001964]; synaptic vesicle exocytosis [GO:0016079]; synaptic vesicle priming [GO:0016082] GO:0000139; GO:0001964; GO:0005509; GO:0005789; GO:0007009; GO:0007605; GO:0010996; GO:0016079; GO:0016082; GO:0016323; GO:0030672; GO:0035612; GO:0042995; GO:0048787; GO:0050885 19650 XM_029355930.2 33 0 0 0 0 NA NA NA NA NA NA 19651 XM_044320475.1 88 20 87 41 12 NA NA NA NA NA NA 19652 XM_044321020.1 54 30 70 37 48 NA NA NA NA NA NA 19653 XM_029332261.2 368 133 290 68 172 Q9HCD5 1.21e-30 Nuclear receptor coactivator 5 (NCoA-5) (Coactivator independent of AF-2) (CIA) Homo sapiens (Human) glucose homeostasis [GO:0042593]; insulin receptor signaling pathway [GO:0008286]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of signal transduction [GO:0009966] GO:0000122; GO:0003682; GO:0003714; GO:0003723; GO:0005615; GO:0005654; GO:0008286; GO:0009966; GO:0015629; GO:0042593; GO:0046627 19654 XM_029339359.2 59 0 31 28 0 NA NA NA NA NA NA 19655 XM_044317681.1 0 0 76 54 0 NA NA NA NA NA NA 19656 XM_029355539.2 153 290 98 283 376 NA NA NA NA NA NA 19657 XM_044319042.1 0 0 23 23 0 NA NA NA NA NA NA 19658 XM_044311334.1 1235 289 204 984 23 B0S5N4 0 Plexin A3 Danio rerio (Zebrafish) (Brachydanio rerio) axon extension [GO:0048675]; branching morphogenesis of a nerve [GO:0048755]; embryonic skeletal joint morphogenesis [GO:0060272]; motor neuron axon guidance [GO:0008045]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of collateral sprouting in absence of injury [GO:0048696]; regulation of GTPase activity [GO:0043087]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287] GO:0002116; GO:0005886; GO:0007162; GO:0008045; GO:0008360; GO:0016020; GO:0017154; GO:0030334; GO:0042802; GO:0043087; GO:0048675; GO:0048696; GO:0048755; GO:0050772; GO:0060272; GO:1902287 19659 XM_044323110.1 131 0 169 228 0 NA NA NA NA NA NA 19660 XM_044310853.1 68 90 90 166 12 Q99570 0 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 19661 XM_029354839.2 353 250 109 217 706 NA NA NA NA NA NA 19662 XM_044308409.1 93 21 68 58 23 Q9JHA8 2.35e-66 von Willebrand factor A domain-containing protein 7 (Protein G7c) Mus musculus (Mouse) NA GO:0005576 19663 XR_006391869.1 19 30 12 19 30 NA NA NA NA NA NA 19664 XM_044321371.1 21 41 46 42 127 NA NA NA NA NA NA 19665 XM_044311381.1 80 49 0 47 0 Q95LR0 5.1e-66 Cilia- and flagella-associated protein 91 (CFAP91) (AMY-1-associating protein expressed in testis 1) (AAT-1) (MYCBP/AMY-1-associated testis-expressed protein 1) (Protein MAATS1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) axonemal central apparatus assembly [GO:1904158]; cell differentiation [GO:0030154]; cilium movement [GO:0003341]; spermatogenesis [GO:0007283] GO:0003341; GO:0005739; GO:0005930; GO:0007283; GO:0030154; GO:0031514; GO:1904158 19666 XM_029349730.2 437 308 215 293 225 Q6PBT5 1.39e-180 Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 (EC 1.8.1.-) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005634; GO:0016491; GO:0030017; GO:0050660 19667 XM_029342221.2 57 0 67 79 0 NA NA NA NA NA NA 19668 XM_029358602.2 1101 919 654 1230 1330 Q8K2V1 0 Serine/threonine-protein phosphatase 4 regulatory subunit 1 Mus musculus (Mouse) protein dephosphorylation [GO:0006470] GO:0006470; GO:0019888 19669 XR_006393786.1 2 7 2 9 4 NA NA NA NA NA NA 19670 XM_044317613.1 529 314 263 490 473 P49183 1.93e-78 Deoxyribonuclease-1 (EC 3.1.21.1) (Deoxyribonuclease I) (DNase I) Mus musculus (Mouse) apoptotic process [GO:0006915]; DNA catabolic process [GO:0006308]; DNA catabolic process, endonucleolytic [GO:0000737]; neutrophil activation involved in immune response [GO:0002283]; regulation of acute inflammatory response [GO:0002673]; regulation of neutrophil mediated cytotoxicity [GO:0070948] GO:0000737; GO:0002283; GO:0002673; GO:0003677; GO:0003779; GO:0004530; GO:0004536; GO:0005576; GO:0005634; GO:0005635; GO:0006308; GO:0006915; GO:0042588; GO:0070948 19671 XM_044327175.1 6 0 0 4 0 NA NA NA NA NA NA 19672 XM_029339078.2 0 15 86 385 0 Q8N653 8.51e-25 Leucine-zipper-like transcriptional regulator 1 (LZTR-1) Homo sapiens (Human) negative regulation of Ras protein signal transduction [GO:0046580]; protein ubiquitination [GO:0016567] GO:0005794; GO:0012505; GO:0016567; GO:0031267; GO:0031463; GO:0046580; GO:0055038 19673 XM_029336173.2 4 2 0 1 13 Q924H0 9.82e-44 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide NPFF receptor) Mus musculus (Mouse) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 19674 XM_029345045.2 0 738 1532 1168 69 NA NA NA NA NA NA 19675 XM_044327410.1 1 0 0 10 10 A0A8V1ABE9 1.25e-113 NA NA NA NA 19676 XM_029343608.2 760 421 290 1557 797 P9WKB8 2.96e-23 Putative diacyglycerol O-acyltransferase MT1809 (EC 2.3.1.20) (Putative triacylglycerol synthase MT1809) Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) glycerol metabolic process [GO:0006071]; triglyceride biosynthetic process [GO:0019432] GO:0004144; GO:0006071; GO:0019432 19677 XM_044320287.1 5 33 6 11 9 Q5IS75 3.93e-59 Neuronal acetylcholine receptor subunit beta-3 Pan troglodytes (Chimpanzee) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; response to nicotine [GO:0035094]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271] GO:0004888; GO:0005231; GO:0005886; GO:0007165; GO:0007268; GO:0007271; GO:0022848; GO:0030594; GO:0034220; GO:0035094; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:1904315 19678 XM_029350232.2 0 0 32 216 31 Q9P278 2.17e-95 Folliculin-interacting protein 2 (FNIP1-like protein) (O6-methylguanine-induced apoptosis 1 protein) Homo sapiens (Human) intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein-containing complex assembly [GO:0031334]; protein phosphorylation [GO:0006468]; regulation of protein phosphorylation [GO:0001932] GO:0000122; GO:0001932; GO:0005737; GO:0005765; GO:0005829; GO:0006468; GO:0008630; GO:0031334; GO:0033138; GO:0034451; GO:0042030; GO:0051087 19679 XM_029350232.2 0 0 32 216 31 Q9P278 1.09e-28 Folliculin-interacting protein 2 (FNIP1-like protein) (O6-methylguanine-induced apoptosis 1 protein) Homo sapiens (Human) intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein-containing complex assembly [GO:0031334]; protein phosphorylation [GO:0006468]; regulation of protein phosphorylation [GO:0001932] GO:0000122; GO:0001932; GO:0005737; GO:0005765; GO:0005829; GO:0006468; GO:0008630; GO:0031334; GO:0033138; GO:0034451; GO:0042030; GO:0051087 19680 XM_044307095.1 938 765 493 842 1027 A0A8I6A2H6 2.14e-86 NA NA NA NA 19681 XM_029335245.2 250 156 173 137 233 NA NA NA NA NA NA 19682 XR_006391884.1 221 193 74 369 381 NA NA NA NA NA NA 19683 XM_044312670.1 5 0 0 94 0 NA NA NA NA NA NA 19684 XM_044325157.1 2233 1641 2256 4199 3964 Q90XB6 2.07e-133 Extracellular sulfatase Sulf-1 (qSulf1) (EC 3.1.6.-) Coturnix coturnix (Common quail) (Tetrao coturnix) bone development [GO:0060348]; cartilage condensation [GO:0001502]; cartilage development [GO:0051216]; cell adhesion [GO:0007155]; chondrocyte development [GO:0002063]; embryonic skeletal system development [GO:0048706]; esophagus smooth muscle contraction [GO:0014846]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; heparan sulfate proteoglycan metabolic process [GO:0030201]; innervation [GO:0060384]; kidney development [GO:0001822]; limb joint morphogenesis [GO:0036022]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell migration [GO:0030336]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; negative regulation of prostatic bud formation [GO:0060686]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of Wnt signaling pathway [GO:0030177]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] GO:0001502; GO:0001822; GO:0001937; GO:0002063; GO:0004065; GO:0005509; GO:0005615; GO:0005783; GO:0005794; GO:0005795; GO:0007155; GO:0008449; GO:0009986; GO:0014846; GO:0016525; GO:0030177; GO:0030201; GO:0030336; GO:0030513; GO:0035860; GO:0036022; GO:0040037; GO:0045121; GO:0048010; GO:0048661; GO:0048706; GO:0051216; GO:0060348; GO:0060384; GO:0060686; GO:0090263 19685 XM_044325157.1 2233 1641 2256 4199 3964 Q90XB6 2.7e-34 Extracellular sulfatase Sulf-1 (qSulf1) (EC 3.1.6.-) Coturnix coturnix (Common quail) (Tetrao coturnix) bone development [GO:0060348]; cartilage condensation [GO:0001502]; cartilage development [GO:0051216]; cell adhesion [GO:0007155]; chondrocyte development [GO:0002063]; embryonic skeletal system development [GO:0048706]; esophagus smooth muscle contraction [GO:0014846]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; heparan sulfate proteoglycan metabolic process [GO:0030201]; innervation [GO:0060384]; kidney development [GO:0001822]; limb joint morphogenesis [GO:0036022]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell migration [GO:0030336]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; negative regulation of prostatic bud formation [GO:0060686]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of Wnt signaling pathway [GO:0030177]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] GO:0001502; GO:0001822; GO:0001937; GO:0002063; GO:0004065; GO:0005509; GO:0005615; GO:0005783; GO:0005794; GO:0005795; GO:0007155; GO:0008449; GO:0009986; GO:0014846; GO:0016525; GO:0030177; GO:0030201; GO:0030336; GO:0030513; GO:0035860; GO:0036022; GO:0040037; GO:0045121; GO:0048010; GO:0048661; GO:0048706; GO:0051216; GO:0060348; GO:0060384; GO:0060686; GO:0090263 19686 XM_044322315.1 249 125 44 138 292 NA NA NA NA NA NA 19687 XM_029328490.2 32 2 2 9 14 Q0VAA2 2.45e-52 Leucine-rich repeat-containing protein 74A (Leucine-rich repeat-containing protein 74) Homo sapiens (Human) NA NA 19688 XR_006391586.1 433 214 168 449 410 NA NA NA NA NA NA 19689 XM_029338082.2 542 779 489 871 514 Q2HJF7 0 Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta) (CaMK-II subunit delta) (EC 2.7.11.17) Bos taurus (Bovine) positive regulation of cardiac muscle hypertrophy [GO:0010613]; protein phosphorylation [GO:0006468]; regulation of cellular localization [GO:0060341] GO:0004683; GO:0005516; GO:0005524; GO:0005737; GO:0006468; GO:0010613; GO:0033017; GO:0042383; GO:0043005; GO:0060341; GO:0106310 19690 XR_003827313.2 0 1 14 0 0 NA NA NA NA NA NA 19691 XM_029348829.2 1637 1895 1375 1705 1419 Q9N1Q0 9.42e-51 Small nuclear ribonucleoprotein-associated protein B' (snRNP-B') (snRPB') (Sm protein B') (Sm-B') (SmB') Notamacropus eugenii (Tammar wallaby) (Macropus eugenii) mRNA splicing, via spliceosome [GO:0000398]; spliceosomal snRNP assembly [GO:0000387] GO:0000387; GO:0000398; GO:0003723; GO:0005634; GO:0005683; GO:0005685; GO:0005687; GO:0005829; GO:0034709; GO:0034719; GO:0046540; GO:0071005; GO:0071007 19692 XM_044319944.1 2613 1055 985 1472 1451 Q9NTJ5 0 Phosphatidylinositol-3-phosphatase SAC1 (EC 3.1.3.64) (Phosphatidylinositol-4-phosphate phosphatase) (Suppressor of actin mutations 1-like protein) Homo sapiens (Human) phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856] GO:0000139; GO:0004438; GO:0005783; GO:0005789; GO:0005794; GO:0006661; GO:0016791; GO:0034596; GO:0043812; GO:0046856; GO:0140268 19693 XM_044316646.1 26 64 61 66 137 NA NA NA NA NA NA 19694 XM_029339202.2 862 1593 1685 1802 1958 NA NA NA NA NA NA 19695 XM_029344758.2 38 9 0 25 248 NA NA NA NA NA NA 19696 XM_044324066.1 0 0 0 0 31 Q3KPR5 1.03e-78 Basic immunoglobulin-like variable motif-containing protein Xenopus laevis (African clawed frog) NA GO:0005634; GO:0005737 19697 XM_044320350.1 6 1 1 9 4 NA NA NA NA NA NA 19698 XM_029335846.2 2623 2938 2043 2228 2126 Q9CUS9 8.68e-141 Signal peptide peptidase-like 3 (SPP-like 3) (EC 3.4.23.-) (Intramembrane protease 2) (IMP-2) (Presenilin-like protein 4) Mus musculus (Mouse) membrane protein proteolysis [GO:0033619]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; signal peptide processing [GO:0006465]; T cell receptor signaling pathway [GO:0050852] GO:0005791; GO:0005794; GO:0005886; GO:0006465; GO:0007204; GO:0016020; GO:0030660; GO:0032092; GO:0033116; GO:0033619; GO:0035307; GO:0042500; GO:0042803; GO:0043231; GO:0050852; GO:0070886; GO:0098553; GO:0098554 19699 XM_044311304.1 228 52 149 0 255 Q91W78 1.33e-33 U6 snRNA phosphodiesterase 1 (3'-5' RNA exonuclease USB1) (EC 4.6.1.-) Mus musculus (Mouse) RNA splicing [GO:0008380]; snRNA 3'-end processing [GO:0034472]; U6 snRNA 3'-end processing [GO:0034477] GO:0000175; GO:0005634; GO:0005654; GO:0008380; GO:0016829; GO:0034472; GO:0034477; GO:0045171; GO:1990838 19700 XM_044327549.1 628 479 399 368 494 O75063 2.06e-130 Glycosaminoglycan xylosylkinase (EC 2.7.1.-) (Xylose kinase) Homo sapiens (Human) phosphorylation [GO:0016310]; proteoglycan biosynthetic process [GO:0030166] GO:0000139; GO:0005524; GO:0005654; GO:0005794; GO:0016301; GO:0016310; GO:0016773; GO:0030166; GO:0046872 19701 XR_006396816.1 25 2 17 0 33 NA NA NA NA NA NA 19702 XR_006393432.1 1099 171 296 304 428 O42449 2.5e-41 Type I iodothyronine deiodinase (EC 1.21.99.4) (5DI) (DIOI) (Type 1 DI) (Type-I 5'-deiodinase) Oreochromis niloticus (Nile tilapia) (Tilapia nilotica) hormone biosynthetic process [GO:0042446]; regulation of neural retina development [GO:0061074] GO:0004800; GO:0005789; GO:0042446; GO:0061074 19703 XM_044316262.1 5 3 0 10 35 A2AJ76 2.92e-30 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 19704 XM_044316262.1 5 3 0 10 35 A2AJ76 2.03e-28 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 19705 XM_044316262.1 5 3 0 10 35 A2AJ76 1.71e-27 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 19706 XM_044316262.1 5 3 0 10 35 A2AJ76 1.22e-23 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 19707 XM_044316262.1 5 3 0 10 35 A2AJ76 1.74e-23 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 19708 XM_044316262.1 5 3 0 10 35 A2AJ76 2.5e-23 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 19709 XM_044316262.1 5 3 0 10 35 A2AJ76 5.49e-22 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 19710 XM_044316262.1 5 3 0 10 35 A2AJ76 9.75e-21 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 19711 XM_044325957.1 34 21 26 39 14 Q8VDU0 3.1e-43 G-protein-signaling modulator 2 (Pins homolog) Mus musculus (Mouse) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 19712 XM_044325957.1 34 21 26 39 14 Q8VDU0 1.84e-36 G-protein-signaling modulator 2 (Pins homolog) Mus musculus (Mouse) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 19713 XM_044325957.1 34 21 26 39 14 Q8VDU0 1.89e-36 G-protein-signaling modulator 2 (Pins homolog) Mus musculus (Mouse) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 19714 XM_044325957.1 34 21 26 39 14 Q8VDU0 9.55e-35 G-protein-signaling modulator 2 (Pins homolog) Mus musculus (Mouse) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 19715 XM_044325957.1 34 21 26 39 14 Q8VDU0 2.34e-34 G-protein-signaling modulator 2 (Pins homolog) Mus musculus (Mouse) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 19716 XR_006392377.1 124 35 36 46 136 NA NA NA NA NA NA 19717 XM_044314972.1 35 7 30 106 25 NA NA NA NA NA NA 19718 XM_044311115.1 9 0 0 11 9 Q17RP2 2.01e-36 Tigger transposable element-derived protein 6 Homo sapiens (Human) NA GO:0003677; GO:0005634 19719 XR_003825273.2 1 0 18 15 34 NA NA NA NA NA NA 19720 XM_029341176.2 61 20 9 28 34 P50430 2.44e-128 Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S) Rattus norvegicus (Rat) anterior head development [GO:0097065]; autophagy [GO:0006914]; central nervous system development [GO:0007417]; colon epithelial cell migration [GO:0061580]; dermatan sulfate catabolic process [GO:0030209]; positive regulation of neuron projection development [GO:0010976]; regulation of epithelial cell migration [GO:0010632]; response to estrogen [GO:0043627]; response to methylmercury [GO:0051597]; response to nutrient [GO:0007584]; response to pH [GO:0009268] GO:0003943; GO:0004065; GO:0005739; GO:0005764; GO:0005791; GO:0005794; GO:0006914; GO:0007417; GO:0007584; GO:0008484; GO:0009268; GO:0009986; GO:0010632; GO:0010976; GO:0030209; GO:0043627; GO:0043890; GO:0046872; GO:0051597; GO:0061580; GO:0097065 19721 XR_006394512.1 105 79 88 164 259 NA NA NA NA NA NA 19722 XM_029355663.2 8 0 0 0 3 NA NA NA NA NA NA 19723 XM_029336267.2 33 0 33 3 224 NA NA NA NA NA NA 19724 XM_044320226.1 111 563 71 0 153 NA NA NA NA NA NA 19725 XM_029348001.2 123 7 206 196 388 NA NA NA NA NA NA 19726 XR_003828491.2 10826 13467 9192 11506 10430 NA NA NA NA NA NA 19727 XM_029328466.2 830 804 615 841 1027 Q9UHV9 4.7e-41 Prefoldin subunit 2 Homo sapiens (Human) negative regulation of amyloid fibril formation [GO:1905907]; positive regulation of cytoskeleton organization [GO:0051495]; protein folding [GO:0006457]; protein stabilization [GO:0050821] GO:0001540; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0006457; GO:0016272; GO:0044183; GO:0050821; GO:0051082; GO:0051495; GO:0101031; GO:1905907; GO:1990062 19728 XM_044323998.1 0 31 0 0 0 NA NA NA NA NA NA 19729 XM_044321138.1 1 0 0 8 7 NA NA NA NA NA NA 19730 XM_044307751.1 10 84 36 3 16 NA NA NA NA NA NA 19731 XR_006392635.1 21 0 6 4 54 NA NA NA NA NA NA 19732 XM_029324548.2 5971 3345 2897 6519 4912 B7W112 1.68e-57 Aspartic and glutamic acid-rich protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 19733 XM_029324548.2 5971 3345 2897 6519 4912 B7W112 3.47e-48 Aspartic and glutamic acid-rich protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 19734 XM_029347775.2 147 221 116 673 467 Q15643 2e-38 Thyroid receptor-interacting protein 11 (TR-interacting protein 11) (TRIP-11) (Clonal evolution-related gene on chromosome 14 protein) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) Homo sapiens (Human) cartilage development [GO:0051216]; chondrocyte differentiation involved in endochondral bone morphogenesis [GO:0003413]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; Golgi ribbon formation [GO:0090161]; inner ear receptor cell stereocilium organization [GO:0060122]; protein glycosylation [GO:0006486]; transcription by RNA polymerase II [GO:0006366]; ventricular septum development [GO:0003281]; vesicle tethering to Golgi [GO:0099041] GO:0000139; GO:0002079; GO:0002081; GO:0003281; GO:0003413; GO:0003713; GO:0005654; GO:0005793; GO:0005794; GO:0005801; GO:0005856; GO:0006366; GO:0006486; GO:0006888; GO:0007030; GO:0016607; GO:0030133; GO:0031267; GO:0033116; GO:0051216; GO:0060122; GO:0090161; GO:0099041 19735 XM_044320467.1 720 12 651 53 43 NA NA NA NA NA NA 19736 XM_044316271.1 7 6 0 3 21 NA NA NA NA NA NA 19737 XM_029327353.2 53 38 64 62 1 NA NA NA NA NA NA 19738 XM_029331588.2 0 0 128 294 36 NA NA NA NA NA NA 19739 XM_044318026.1 64 109 76 36 188 NA NA NA NA NA NA 19740 XM_029356579.2 259 114 53 125 145 NA NA NA NA NA NA 19741 XM_044322522.1 130 1 469 0 143 NA NA NA NA NA NA 19742 XR_006393730.1 6 0 2 19 7 NA NA NA NA NA NA 19743 XM_029338759.2 1 1516 818 683 450 B3EWZ5 2.32e-113 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 19744 XM_029338759.2 1 1516 818 683 450 B3EWZ5 3.43e-110 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 19745 XM_029338759.2 1 1516 818 683 450 B3EWZ5 5.61e-108 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 19746 XM_029338759.2 1 1516 818 683 450 B3EWZ5 2.03e-106 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 19747 XM_029338759.2 1 1516 818 683 450 B3EWZ5 1.91e-96 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 19748 XM_029338759.2 1 1516 818 683 450 B3EWZ5 2.99e-89 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 19749 XM_029338759.2 1 1516 818 683 450 B3EWZ5 1.3e-80 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 19750 XM_029338759.2 1 1516 818 683 450 B3EWZ5 7.74e-78 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 19751 XM_029338759.2 1 1516 818 683 450 B3EWZ5 7.02e-68 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 19752 XM_029338759.2 1 1516 818 683 450 B3EWZ5 2.71e-63 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 19753 XM_029338759.2 1 1516 818 683 450 B3EWZ5 1.61e-50 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 19754 XM_029338759.2 1 1516 818 683 450 B3EWZ5 4.67e-50 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 19755 XM_029338759.2 1 1516 818 683 450 B3EWZ5 2.66e-46 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 19756 XM_029338759.2 1 1516 818 683 450 B3EWZ5 1.77e-40 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 19757 XM_029338759.2 1 1516 818 683 450 B3EWZ5 6.78e-37 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 19758 XM_029338759.2 1 1516 818 683 450 B3EWZ5 1.48e-35 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 19759 XM_029338759.2 1 1516 818 683 450 B3EWZ5 5.31e-29 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 19760 XM_029338759.2 1 1516 818 683 450 B3EWZ5 1.94e-26 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 19761 XM_029338759.2 1 1516 818 683 450 B3EWZ5 3.91e-26 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 19762 XM_044307732.1 323 116 73 18 104 NA NA NA NA NA NA 19763 XM_029323843.2 464 101 397 562 315 Q99697 4.92e-31 Pituitary homeobox 2 (ALL1-responsive protein ARP1) (Homeobox protein PITX2) (Paired-like homeodomain transcription factor 2) (RIEG bicoid-related homeobox transcription factor) (Solurshin) Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cardiac neural crest cell migration involved in outflow tract morphogenesis [GO:0003253]; cell proliferation involved in outflow tract morphogenesis [GO:0061325]; deltoid tuberosity development [GO:0035993]; determination of left/right symmetry [GO:0007368]; embryonic heart tube left/right pattern formation [GO:0060971]; hair cell differentiation [GO:0035315]; iris morphogenesis [GO:0061072]; left/right axis specification [GO:0070986]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; positive regulation of transcription by RNA polymerase II [GO:0045944]; prolactin secreting cell differentiation [GO:0060127]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; somatotropin secreting cell differentiation [GO:0060126]; spleen development [GO:0048536] GO:0000122; GO:0000785; GO:0000976; GO:0000978; GO:0000981; GO:0001227; GO:0003253; GO:0003700; GO:0005634; GO:0005654; GO:0005667; GO:0006355; GO:0006357; GO:0007368; GO:0009653; GO:0035315; GO:0035993; GO:0042476; GO:0042802; GO:0042803; GO:0043010; GO:0043021; GO:0045944; GO:0048536; GO:0051219; GO:0060126; GO:0060127; GO:0060971; GO:0061072; GO:0061325; GO:0061629; GO:0070986; GO:0140297; GO:1990837 19764 XM_029336293.2 449 327 281 244 191 NA NA NA NA NA NA 19765 XM_044307073.1 203 45 213 97 106 NA NA NA NA NA NA 19766 XM_029327310.2 0 0 0 20 15 NA NA NA NA NA NA 19767 XM_044315487.1 11 0 0 66 3 NA NA NA NA NA NA 19768 XM_029323727.2 655 619 548 440 521 P49356 1.6e-152 Protein farnesyltransferase subunit beta (FTase-beta) (EC 2.5.1.58) (CAAX farnesyltransferase subunit beta) (Ras proteins prenyltransferase subunit beta) Homo sapiens (Human) lipid metabolic process [GO:0006629]; protein farnesylation [GO:0018343]; protein prenylation [GO:0018342] GO:0004660; GO:0005829; GO:0005875; GO:0005965; GO:0006629; GO:0008270; GO:0018342; GO:0018343 19769 XM_029335620.2 206 132 97 84 113 Q96IR2 6.79e-33 Zinc finger protein 845 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 19770 XM_029335620.2 206 132 97 84 113 Q96IR2 8.8e-28 Zinc finger protein 845 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 19771 XM_029335620.2 206 132 97 84 113 Q96IR2 5.1e-27 Zinc finger protein 845 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 19772 XM_029335620.2 206 132 97 84 113 Q96IR2 4.97e-26 Zinc finger protein 845 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 19773 XM_029335620.2 206 132 97 84 113 Q96IR2 2.92e-25 Zinc finger protein 845 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 19774 XM_029335620.2 206 132 97 84 113 Q96IR2 7.99e-25 Zinc finger protein 845 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 19775 XM_029335620.2 206 132 97 84 113 Q96IR2 9.59e-24 Zinc finger protein 845 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 19776 XM_029335620.2 206 132 97 84 113 Q96IR2 1.21e-22 Zinc finger protein 845 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 19777 XM_029335620.2 206 132 97 84 113 Q96IR2 3.48e-22 Zinc finger protein 845 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 19778 XM_029329679.2 144 174 222 273 540 NA NA NA NA NA NA 19779 XM_029323535.2 5133 4796 2784 3029 2352 O43808 2.9e-108 Peroxisomal membrane protein PMP34 (34 kDa peroxisomal membrane protein) (Solute carrier family 25 member 17) Homo sapiens (Human) ATP transport [GO:0015867]; fatty acid alpha-oxidation [GO:0001561]; fatty acid beta-oxidation [GO:0006635]; fatty acid transport [GO:0015908] GO:0000295; GO:0001561; GO:0005347; GO:0005777; GO:0005778; GO:0005829; GO:0006635; GO:0015217; GO:0015228; GO:0015230; GO:0015867; GO:0015908; GO:0016020; GO:0044610; GO:0051087; GO:0051724; GO:0080122 19780 XM_029342422.2 138 132 83 147 184 Q96H55 0 Unconventional myosin-XIX (Myosin head domain-containing protein 1) Homo sapiens (Human) actin filament organization [GO:0007015]; mitochondrion migration along actin filament [GO:0034642]; mitocytosis [GO:0160040]; regulation of cytokinesis [GO:0032465]; regulation of mitochondrial fission [GO:0090140]; vesicle transport along actin filament [GO:0030050] GO:0000146; GO:0003779; GO:0005524; GO:0005737; GO:0005739; GO:0005741; GO:0005829; GO:0007015; GO:0015629; GO:0016459; GO:0016887; GO:0030050; GO:0031982; GO:0032027; GO:0032465; GO:0034642; GO:0051015; GO:0060002; GO:0090140; GO:0160040 19781 XR_006393891.1 41 2 25 5 151 NA NA NA NA NA NA 19782 XM_029328482.2 305 276 1260 2320 98 NA NA NA NA NA NA 19783 XR_003823044.2 22 44 0 0 18 NA NA NA NA NA NA 19784 XM_029335707.2 0 0 0 32 0 Q9NZM1 0 Myoferlin (Fer-1-like protein 3) Homo sapiens (Human) blood circulation [GO:0008015]; membrane fusion [GO:0061025]; muscle contraction [GO:0006936]; plasma membrane organization [GO:0007009]; plasma membrane repair [GO:0001778]; T-tubule organization [GO:0033292] GO:0001778; GO:0005543; GO:0005635; GO:0005886; GO:0005901; GO:0006936; GO:0007009; GO:0008015; GO:0030659; GO:0031410; GO:0031965; GO:0033292; GO:0043231; GO:0046872; GO:0061025; GO:0070062 19785 XM_044311479.1 29 0 6 0 8 NA NA NA NA NA NA 19786 XM_044322554.1 1276 1788 949 835 603 NA NA NA NA NA NA 19787 XM_029337697.2 439 770 543 534 792 Q9UA35 4.44e-145 Solute carrier family 28 member 3 (Concentrative Na(+)-nucleoside cotransporter 3) (hfCNT) Eptatretus stoutii (Pacific hagfish) NA GO:0005337; GO:0005886; GO:0015293 19788 XM_029324093.2 2 22 0 0 0 Q5M7N9 1.75e-80 Extended synaptotagmin-3 (E-Syt3) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) endoplasmic reticulum-plasma membrane tethering [GO:0061817]; lipid transport [GO:0006869] GO:0005789; GO:0005886; GO:0006869; GO:0008289; GO:0046872; GO:0061817; GO:0140268 19789 XM_029349557.2 29 32 32 34 42 Q4U4D2 9.07e-46 Melanopsin (Opsin-4) Podarcis siculus (Italian wall lizard) phototransduction [GO:0007602]; visual perception [GO:0007601] GO:0004930; GO:0005886; GO:0007601; GO:0007602; GO:0009881 19790 XR_006394977.1 337 0 132 102 149 NA NA NA NA NA NA 19791 XR_006396590.1 16 25 41 53 99 NA NA NA NA NA NA 19792 XM_044319837.1 411 714 222 280 224 NA NA NA NA NA NA 19793 XM_044309347.1 167 53 53 121 665 NA NA NA NA NA NA 19794 XM_029353179.2 145 47 53 169 134 NA NA NA NA NA NA 19795 XR_006391821.1 15 0 0 0 0 NA NA NA NA NA NA 19796 XM_029327140.2 1027 2038 978 1109 1342 Q9NRW4 4.21e-64 Dual specificity protein phosphatase 22 (EC 3.1.3.16) (EC 3.1.3.48) (JNK-stimulatory phosphatase-1) (JSP-1) (Low molecular weight dual specificity phosphatase 2) (LMW-DSP2) (Mitogen-activated protein kinase phosphatase x) (MAP kinase phosphatase x) (MKP-x) Homo sapiens (Human) cellular response to epidermal growth factor stimulus [GO:0071364]; dephosphorylation [GO:0016311]; negative regulation of cell migration [GO:0030336]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903996]; negative regulation of T cell activation [GO:0050868]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-tyrosine dephosphorylation [GO:0035335]; positive regulation of JNK cascade [GO:0046330]; regulation of cell population proliferation [GO:0042127]; signal transduction [GO:0007165]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0000122; GO:0002710; GO:0004725; GO:0004726; GO:0005737; GO:0005829; GO:0005886; GO:0007165; GO:0007179; GO:0008138; GO:0016311; GO:0017018; GO:0030336; GO:0031941; GO:0035335; GO:0042127; GO:0046330; GO:0050860; GO:0050868; GO:0051895; GO:0061851; GO:0071364; GO:1903996; GO:1990782 19797 XM_029349678.2 0 0 5 0 7 Q9EQD2 4.73e-25 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 19798 XM_044319255.1 906 851 446 505 539 NA NA NA NA NA NA 19799 XR_006394160.1 40 4 0 0 43 NA NA NA NA NA NA 19800 XM_029335372.2 343 318 190 272 284 Q16667 6.84e-46 Cyclin-dependent kinase inhibitor 3 (EC 3.1.3.16) (EC 3.1.3.48) (CDK2-associated dual-specificity phosphatase) (Cyclin-dependent kinase interactor 1) (Cyclin-dependent kinase-interacting protein 2) (Kinase-associated phosphatase) Homo sapiens (Human) G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of cell population proliferation [GO:0008285]; protein dephosphorylation [GO:0006470]; regulation of cell cycle [GO:0051726]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079] GO:0000079; GO:0000082; GO:0004722; GO:0004725; GO:0005737; GO:0005829; GO:0006470; GO:0008138; GO:0008285; GO:0017018; GO:0048471; GO:0051726 19801 XR_003824420.2 0 19 0 0 0 NA NA NA NA NA NA 19802 XR_006397678.1 21 47 11 76 21 NA NA NA NA NA NA 19803 XM_029341906.2 0 0 0 13 22 P79385 1.28e-23 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (SED1) (Sperm surface protein SP47) (PP47) Sus scrofa (Pig) angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; single fertilization [GO:0007338] GO:0001525; GO:0002080; GO:0005576; GO:0007155; GO:0007338 19804 XM_029352301.2 2525 3422 1772 1861 1578 Q66IM5 2.83e-27 Protein NATD1 (N-acetyltransferase domain-containing protein 1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA NA 19805 XM_044318453.1 12 11 24 8 6 P92176 2.05e-22 Actin-2 (EC 3.6.4.-) Lumbricus terrestris (Common earthworm) NA GO:0005524; GO:0005737; GO:0005856; GO:0016787 19806 XM_044318548.1 64 14 28 17 35 NA NA NA NA NA NA 19807 XM_029323590.2 1206 383 54 535 309 Q7L014 0 Probable ATP-dependent RNA helicase DDX46 (EC 3.6.4.13) (DEAD box protein 46) (PRP5 homolog) Homo sapiens (Human) mRNA splicing, via spliceosome [GO:0000398]; U2-type prespliceosome assembly [GO:1903241] GO:0000398; GO:0001650; GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005654; GO:0005681; GO:0005686; GO:0015030; GO:0016020; GO:0016607; GO:0016887; GO:1903241 19808 XM_044313119.1 52 1 19 0 148 C3ZQF9 1.02e-21 QRFP-like peptide receptor Branchiostoma floridae (Florida lancelet) (Amphioxus) cellular response to peptide [GO:1901653]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:1901653 19809 XM_044310079.1 68 0 0 31 16 NA NA NA NA NA NA 19810 XR_006394093.1 0 0 4 22 0 NA NA NA NA NA NA 19811 XR_003826256.2 1 0 0 9 16 NA NA NA NA NA NA 19812 XR_006392800.1 0 0 0 13 0 NA NA NA NA NA NA 19813 XR_006391430.1 684 3075 1159 260 175 NA NA NA NA NA NA 19814 XM_029327775.2 864 895 632 761 541 F4KF65 1.05e-35 Importin subunit alpha-9 (IMPa-9) Arabidopsis thaliana (Mouse-ear cress) NLS-bearing protein import into nucleus [GO:0006607] GO:0005634; GO:0005635; GO:0005737; GO:0006607; GO:0008139; GO:0061608 19815 XM_029332281.2 584 441 324 374 490 NA NA NA NA NA NA 19816 XR_006393757.1 112 38 18 130 111 NA NA NA NA NA NA 19817 XM_029332911.2 32 122 30 0 1 NA NA NA NA NA NA 19818 XM_044317164.1 9 5 7 7 7 NA NA NA NA NA NA 19819 XM_044318339.1 0 1 12 2 4 NA NA NA NA NA NA 19820 XM_029355433.2 9267 8095 5030 7653 7614 Q01314 0 RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (RAC-PK-alpha) Bos taurus (Bovine) apoptotic process [GO:0006915]; carbohydrate transport [GO:0008643]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; nervous system development [GO:0007399]; peptidyl-serine phosphorylation [GO:0018105]; phosphorylation [GO:0016310]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of lipid biosynthetic process [GO:0046889]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of cell migration [GO:0030334]; regulation of neuron projection development [GO:0010975]; regulation of translation [GO:0006417]; response to growth factor [GO:0070848]; response to growth hormone [GO:0060416]; response to insulin-like growth factor stimulus [GO:1990418] GO:0001938; GO:0004674; GO:0005516; GO:0005524; GO:0005634; GO:0005737; GO:0005886; GO:0005978; GO:0006006; GO:0006417; GO:0006468; GO:0006915; GO:0007399; GO:0008643; GO:0010975; GO:0016310; GO:0018105; GO:0030334; GO:0042981; GO:0043154; GO:0046889; GO:0060416; GO:0070848; GO:0090201; GO:0099104; GO:0106310; GO:1990418 19821 XM_029324961.2 147 82 47 175 93 NA NA NA NA NA NA 19822 XM_029345733.2 352 521 316 383 422 Q9WU01 7.22e-65 KH domain-containing, RNA-binding, signal transduction-associated protein 2 (Sam68-like mammalian protein 1) (SLM-1) (mSLM-1) Mus musculus (Mouse) mRNA processing [GO:0006397]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of mRNA splicing, via spliceosome [GO:0048024] GO:0000381; GO:0003729; GO:0005634; GO:0006397; GO:0008143; GO:0008266; GO:0017124; GO:0042169; GO:0048024 19823 XM_029340281.2 0 376 422 424 129 Q5RA50 9.42e-27 Protein FAM124A Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA NA 19824 XM_044324375.1 1071 676 713 1105 1601 F1SC07 0 Dynein axonemal heavy chain 11 (Axonemal beta dynein heavy chain 11) (Ciliary dynein heavy chain 11) Sus scrofa (Pig) cilium movement [GO:0003341]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0031514; GO:0045505; GO:0051959; GO:0097729 19825 XM_044324375.1 1071 676 713 1105 1601 F1SC07 3.85e-76 Dynein axonemal heavy chain 11 (Axonemal beta dynein heavy chain 11) (Ciliary dynein heavy chain 11) Sus scrofa (Pig) cilium movement [GO:0003341]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0031514; GO:0045505; GO:0051959; GO:0097729 19826 XM_044324375.1 1071 676 713 1105 1601 F1SC07 7.64e-31 Dynein axonemal heavy chain 11 (Axonemal beta dynein heavy chain 11) (Ciliary dynein heavy chain 11) Sus scrofa (Pig) cilium movement [GO:0003341]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0031514; GO:0045505; GO:0051959; GO:0097729 19827 XM_044318712.1 69 25 15 47 29 A7SVT1 0 Protein adenylyltransferase Fic (EC 2.7.7.108) (De-AMPylase Fic) (EC 3.1.4.-) Nematostella vectensis (Starlet sea anemone) NA GO:0005524; GO:0016020; GO:0016787; GO:0070733 19828 XM_044319998.1 96 115 91 518 301 NA NA NA NA NA NA 19829 XM_029331405.2 944 589 405 1680 1389 Q5BKF8 1.68e-114 Cyclin-L2 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) regulation of transcription by RNA polymerase II [GO:0006357] GO:0006357; GO:0016538; GO:0016607 19830 XM_044314227.1 9 11 13 14 75 NA NA NA NA NA NA 19831 XM_029343984.2 1649 1200 1276 2342 2225 A0JNW5 1.06e-106 Bridge-like lipid transfer protein family member 3B (Syntaxin-6 Habc-interacting protein of 164 kDa) (UHRF1-binding protein 1-like) Homo sapiens (Human) early endosome to Golgi transport [GO:0034498]; intermembrane lipid transfer [GO:0120009] GO:0005769; GO:0005829; GO:0034498; GO:0042803; GO:0062069; GO:0120009; GO:0120013 19832 XM_044306924.1 6 0 28 136 2 NA NA NA NA NA NA 19833 XR_006397270.1 6 0 0 2 0 NA NA NA NA NA NA 19834 XM_029345456.2 312 199 160 212 269 Q24K03 1.89e-55 THUMP domain-containing protein 1 Bos taurus (Bovine) tRNA modification [GO:0006400] GO:0003723; GO:0006400 19835 XM_044322417.1 244 251 111 133 254 NA NA NA NA NA NA 19836 XR_006392737.1 19 5 0 0 0 NA NA NA NA NA NA 19837 XM_044308066.1 1961 539 412 1241 1794 NA NA NA NA NA NA 19838 XM_029349427.2 18 0 21 25 51 P20420 3.57e-63 Neuronal acetylcholine receptor subunit alpha-5 Rattus norvegicus (Rat) behavioral response to nicotine [GO:0035095]; cellular response to nicotine [GO:0071316]; chemical synaptic transmission [GO:0007268]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; hippocampus development [GO:0021766]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system process [GO:0050877]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of membrane potential [GO:0042391]; regulation of neuronal action potential [GO:0098908]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to nicotine [GO:0035094]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271] GO:0005231; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0007271; GO:0015464; GO:0021766; GO:0022848; GO:0030425; GO:0030594; GO:0034220; GO:0035094; GO:0035095; GO:0042166; GO:0042391; GO:0043005; GO:0043025; GO:0044877; GO:0045202; GO:0045211; GO:0050877; GO:0050966; GO:0051899; GO:0071316; GO:0098691; GO:0098793; GO:0098908; GO:0099171; GO:1904315; GO:2000300 19839 XM_044326773.1 4 6 10 7 0 NA NA NA NA NA NA 19840 XM_029338557.2 91 16 55 0 183 NA NA NA NA NA NA 19841 XM_044324844.1 2149 1078 923 3773 3580 P20909 1.31e-45 Collagen alpha-1(XI) chain Rattus norvegicus (Rat) cartilage condensation [GO:0001502]; cartilage development [GO:0051216]; chondrocyte development [GO:0002063]; collagen fibril organization [GO:0030199]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; embryonic skeletal system morphogenesis [GO:0048704]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; heart morphogenesis [GO:0003007]; inner ear morphogenesis [GO:0042472]; ossification [GO:0001503]; proteoglycan metabolic process [GO:0006029]; sensory perception of sound [GO:0007605]; skeletal system morphogenesis [GO:0048705]; tendon development [GO:0035989]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; visual perception [GO:0007601] GO:0001502; GO:0001503; GO:0002063; GO:0003007; GO:0005201; GO:0005581; GO:0005592; GO:0005615; GO:0006029; GO:0007601; GO:0007605; GO:0008201; GO:0030198; GO:0030199; GO:0031012; GO:0035987; GO:0035989; GO:0042472; GO:0046872; GO:0048704; GO:0048705; GO:0050910; GO:0051216; GO:0055010; GO:0062023; GO:1904399 19842 XM_044311090.1 823 425 572 508 1319 NA NA NA NA NA NA 19843 XM_044325599.1 73 28 70 0 0 NA NA NA NA NA NA 19844 XM_044308242.1 1735 1290 1054 2001 1986 NA NA NA NA NA NA 19845 XM_044312035.1 416 25 533 39 2561 Q6LAF1 9.1e-46 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 19846 XR_006392958.1 41 2 25 5 151 NA NA NA NA NA NA 19847 XM_029325818.2 72 3 6 91 81 NA NA NA NA NA NA 19848 XM_029333493.2 141 179 92 126 144 Q4JL91 2.72e-37 Inositol-pentakisphosphate 2-kinase (EC 2.7.1.158) (Inositol-1,3,4,5,6-pentakisphosphate 2-kinase) (Ins(1,3,4,5,6)P5 2-kinase) (InsP5 2-kinase) Danio rerio (Zebrafish) (Brachydanio rerio) determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; inositol phosphate biosynthetic process [GO:0032958]; inositol phosphorylation [GO:0052746]; melanosome transport [GO:0032402] GO:0005524; GO:0005576; GO:0005634; GO:0005737; GO:0005813; GO:0007368; GO:0032402; GO:0032958; GO:0035299; GO:0036064; GO:0052746; GO:0060287 19849 XM_029348451.2 5455 5561 3343 3996 2282 P42568 7.78e-57 Protein AF-9 (ALL1-fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3) Homo sapiens (Human) anterior/posterior pattern specification [GO:0009952]; chromatin remodeling [GO:0006338]; gene expression [GO:0010467]; hematopoietic stem cell differentiation [GO:0060218]; histone acetylation [GO:0016573]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; regulation of chromatin organization [GO:1902275]; regulation of stem cell division [GO:2000035]; regulation of transcription by RNA polymerase II [GO:0006357]; segment specification [GO:0007379] GO:0003677; GO:0003682; GO:0005634; GO:0005654; GO:0005829; GO:0006338; GO:0006357; GO:0007379; GO:0008023; GO:0009952; GO:0010467; GO:0016573; GO:0032783; GO:0035267; GO:0042393; GO:0045893; GO:0060090; GO:0060218; GO:0070062; GO:0070577; GO:0090090; GO:0140030; GO:1902275; GO:2000035; GO:2000096 19850 XM_029354086.2 0 0 17 42 0 Q91175 8.1e-48 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (MAR1) Oryzias latipes (Japanese rice fish) (Japanese killifish) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of vasoconstriction [GO:0045907] GO:0001996; GO:0004930; GO:0004937; GO:0005886; GO:0007200; GO:0007204; GO:0007267; GO:0043410; GO:0045907; GO:0071880 19851 XM_029355295.2 4188 4036 2478 3628 3236 P21580 6.97e-66 Tumor necrosis factor alpha-induced protein 3 (TNF alpha-induced protein 3) (EC 2.3.2.-) (EC 3.4.19.12) (OTU domain-containing protein 7C) (Putative DNA-binding protein A20) (Zinc finger protein A20) [Cleaved into: A20p50; A20p37] Homo sapiens (Human) apoptotic process [GO:0006915]; B-1 B cell homeostasis [GO:0001922]; cell migration [GO:0016477]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cytoskeleton organization [GO:0007010]; establishment of protein localization to vacuole [GO:0072666]; inflammatory response [GO:0006954]; negative regulation of B cell activation [GO:0050869]; negative regulation of bone resorption [GO:0045779]; negative regulation of CD40 signaling pathway [GO:2000349]; negative regulation of chronic inflammatory response [GO:0002677]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [GO:0070429]; negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070433]; negative regulation of osteoclast proliferation [GO:0090291]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of toll-like receptor 3 signaling pathway [GO:0034140]; negative regulation of toll-like receptor 4 signaling pathway [GO:0034144]; negative regulation of toll-like receptor 5 signaling pathway [GO:0034148]; negative regulation of tumor necrosis factor production [GO:0032720]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; positive regulation of hepatocyte proliferation [GO:2000347]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of Wnt signaling pathway [GO:0030177]; protein deubiquitination [GO:0016579]; protein deubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0071947]; protein K11-linked deubiquitination [GO:0035871]; protein K29-linked deubiquitination [GO:0035523]; protein K33-linked deubiquitination [GO:1990168]; protein K48-linked deubiquitination [GO:0071108]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked deubiquitination [GO:0070536]; regulation of defense response to virus by host [GO:0050691]; regulation of germinal center formation [GO:0002634]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; regulation of vascular wound healing [GO:0061043]; response to molecule of bacterial origin [GO:0002237]; response to muramyl dipeptide [GO:0032495]; tolerance induction to lipopolysaccharide [GO:0072573] GO:0001922; GO:0002020; GO:0002237; GO:0002634; GO:0002677; GO:0003677; GO:0004842; GO:0004843; GO:0005634; GO:0005737; GO:0005764; GO:0005829; GO:0006915; GO:0006954; GO:0007010; GO:0008022; GO:0008270; GO:0010803; GO:0016477; GO:0016579; GO:0019900; GO:0030177; GO:0031397; GO:0032088; GO:0032495; GO:0032691; GO:0032703; GO:0032715; GO:0032720; GO:0034136; GO:0034140; GO:0034144; GO:0034148; GO:0035523; GO:0035871; GO:0042802; GO:0043124; GO:0043130; GO:0043621; GO:0045732; GO:0045736; GO:0045779; GO:0045824; GO:0048662; GO:0050691; GO:0050728; GO:0050869; GO:0061043; GO:0061578; GO:0070062; GO:0070301; GO:0070423; GO:0070429; GO:0070433; GO:0070530; GO:0070536; GO:0070936; GO:0071108; GO:0071222; GO:0071947; GO:0072573; GO:0072666; GO:0090291; GO:1902042; GO:1990168; GO:2000347; GO:2000349; GO:2000352 19852 XM_044320759.1 13 8 28 3 15 NA NA NA NA NA NA 19853 XM_029346097.2 256 162 64 117 159 P43235 4.87e-58 Cathepsin K (EC 3.4.22.38) (Cathepsin O) (Cathepsin O2) (Cathepsin X) Homo sapiens (Human) autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to zinc ion starvation [GO:0034224]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; intramembranous ossification [GO:0001957]; mononuclear cell differentiation [GO:1903131]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; response to ethanol [GO:0045471]; response to insulin [GO:0032868]; response to organic cyclic compound [GO:0014070]; thyroid hormone generation [GO:0006590] GO:0000422; GO:0001957; GO:0001968; GO:0004197; GO:0004252; GO:0005518; GO:0005576; GO:0005615; GO:0005654; GO:0005764; GO:0006508; GO:0006590; GO:0006955; GO:0008234; GO:0009897; GO:0014070; GO:0016324; GO:0022617; GO:0030574; GO:0032868; GO:0034224; GO:0036021; GO:0043202; GO:0043231; GO:0043394; GO:0045453; GO:0045471; GO:0051603; GO:0061037; GO:0071356; GO:0071560; GO:1903131 19854 XM_044314201.1 201 1 5 58 15 Q96AY4 3.07e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19855 XM_044314201.1 201 1 5 58 15 Q96AY4 7.82e-70 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19856 XM_044314201.1 201 1 5 58 15 Q96AY4 3.04e-69 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19857 XM_044314201.1 201 1 5 58 15 Q96AY4 5.21e-66 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19858 XM_044314201.1 201 1 5 58 15 Q96AY4 1.82e-65 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19859 XM_044314201.1 201 1 5 58 15 Q96AY4 5.37e-55 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19860 XM_044314201.1 201 1 5 58 15 Q96AY4 2.74e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19861 XM_029332805.2 450 317 275 304 298 Q9UPM8 1.74e-164 AP-4 complex subunit epsilon-1 (AP-4 adaptor complex subunit epsilon) (Adaptor-related protein complex 4 subunit epsilon-1) (Epsilon subunit of AP-4) (Epsilon-adaptin) Homo sapiens (Human) protein localization [GO:0008104]; protein targeting [GO:0006605]; vesicle-mediated transport [GO:0016192] GO:0005802; GO:0006605; GO:0008104; GO:0016192; GO:0030124; GO:0031904; GO:0032588; GO:0140312 19862 XM_029355685.2 34906 23487 20222 21175 17765 P24610 3.45e-62 Paired box protein Pax-3 Mus musculus (Mouse) anatomical structure development [GO:0048856]; cardiac muscle cell differentiation [GO:0055007]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; developmental pigmentation [GO:0048066]; heart development [GO:0007507]; mammary gland specification [GO:0060594]; muscle organ development [GO:0007517]; myoblast migration [GO:0051451]; myoblast proliferation [GO:0051450]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural crest cell migration [GO:0001755]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; neuron fate commitment [GO:0048663]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of somitogenesis [GO:0014807]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal muscle cell differentiation [GO:0035914]; skeletal muscle organ development [GO:0060538]; spinal cord association neuron differentiation [GO:0021527]; stem cell proliferation [GO:0072089] GO:0000122; GO:0000978; GO:0000981; GO:0001221; GO:0001755; GO:0001843; GO:0003682; GO:0003700; GO:0005634; GO:0005654; GO:0005667; GO:0006357; GO:0007507; GO:0007517; GO:0008283; GO:0014807; GO:0016477; GO:0021527; GO:0021915; GO:0035914; GO:0043565; GO:0045893; GO:0045944; GO:0048066; GO:0048663; GO:0048856; GO:0051450; GO:0051451; GO:0055007; GO:0060538; GO:0060594; GO:0071837; GO:0072089; GO:1990837; GO:2000648 19863 XM_029326681.2 128 5 84 91 182 Q8N9H8 2.14e-95 Exonuclease mut-7 homolog (EC 3.1.-.-) (Exonuclease 3'-5' domain-containing protein 3) Homo sapiens (Human) NA GO:0003676; GO:0008408; GO:0046872 19864 XM_044327184.1 32 37 76 67 36 NA NA NA NA NA NA 19865 XM_044322033.1 0 43 91 45 98 NA NA NA NA NA NA 19866 XM_044307773.1 24 6 10 15 33 P79385 1.94e-22 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (SED1) (Sperm surface protein SP47) (PP47) Sus scrofa (Pig) angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; single fertilization [GO:0007338] GO:0001525; GO:0002080; GO:0005576; GO:0007155; GO:0007338 19867 XM_029343053.2 69 154 109 77 183 Q8BH86 2.38e-71 D-glutamate cyclase, mitochondrial (EC 4.2.1.48) Mus musculus (Mouse) glutamate metabolic process [GO:0006536] GO:0005739; GO:0005759; GO:0006536; GO:0047820 19868 XM_029339300.2 500 255 279 390 616 NA NA NA NA NA NA 19869 XM_044329133.1 20 16 7 32 4 Q96AY4 5.97e-136 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19870 XM_044329133.1 20 16 7 32 4 Q96AY4 1.67e-113 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19871 XM_044329133.1 20 16 7 32 4 Q96AY4 5.44e-111 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19872 XM_044329133.1 20 16 7 32 4 Q96AY4 5.14e-106 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19873 XM_044329133.1 20 16 7 32 4 Q96AY4 2.1e-52 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19874 XM_044329133.1 20 16 7 32 4 Q96AY4 9.86e-47 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19875 XM_044329133.1 20 16 7 32 4 Q96AY4 2.3e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19876 XM_029345815.2 179 218 175 158 279 A7SNN9 3.43e-149 Queuosine salvage protein Nematostella vectensis (Starlet sea anemone) tRNA modification [GO:0006400]; tRNA-guanine transglycosylation [GO:0101030] GO:0006400; GO:0101030 19877 XM_044312822.1 0 15 21 43 0 NA NA NA NA NA NA 19878 XM_044309464.1 29 13 34 113 1 NA NA NA NA NA NA 19879 XR_006392893.1 41 2 25 5 151 NA NA NA NA NA NA 19880 XM_029357786.2 12 0 57 0 0 Q9EQD2 7.22e-46 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 19881 XM_044306858.1 0 0 5 7 28 Q593B6 3e-39 Coagulation factor V [Cleaved into: Coagulation factor V heavy chain; Coagulation factor V light chain] Pseudonaja textilis (Eastern brown snake) blood coagulation [GO:0007596]; positive regulation of peptidase activity [GO:0010952] GO:0005507; GO:0005576; GO:0007596; GO:0010952; GO:0016504; GO:0090729 19882 XM_044306858.1 0 0 5 7 28 Q593B6 8.01e-31 Coagulation factor V [Cleaved into: Coagulation factor V heavy chain; Coagulation factor V light chain] Pseudonaja textilis (Eastern brown snake) blood coagulation [GO:0007596]; positive regulation of peptidase activity [GO:0010952] GO:0005507; GO:0005576; GO:0007596; GO:0010952; GO:0016504; GO:0090729 19883 XM_029339629.2 3422 2816 1273 2445 3368 Q90XN9 1.54e-32 Homeobox protein HMX3-B (Homeobox protein H6 family member 3-B) (Homeobox protein Nkx-5.1.2) (OlNkx-5.1.2) Oryzias latipes (Japanese rice fish) (Japanese killifish) cell differentiation [GO:0030154]; nervous system development [GO:0007399]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0007399; GO:0030154 19884 XM_029358203.2 86 37 5 14 6 NA NA NA NA NA NA 19885 XM_029343570.2 0 1 3 9 10 NA NA NA NA NA NA 19886 XR_006393063.1 41 2 25 5 151 NA NA NA NA NA NA 19887 XM_029332663.2 773 645 471 638 733 Q5ZJN2 3.3e-75 Ras-related protein Rab-11A (EC 3.6.5.2) Gallus gallus (Chicken) cell cycle [GO:0007049]; exocytosis [GO:0006887]; melanosome transport [GO:0032402]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; vesicle-mediated transport [GO:0016192] GO:0003924; GO:0003925; GO:0005525; GO:0005768; GO:0005794; GO:0006887; GO:0007049; GO:0016192; GO:0030133; GO:0032154; GO:0032402; GO:0045335; GO:0055037; GO:0055038; GO:0098837; GO:0098887 19888 XM_044323407.1 15 0 6 3 37 NA NA NA NA NA NA 19889 XM_044312103.1 0 0 2 3 84 NA NA NA NA NA NA 19890 XM_029334806.2 63 38 67 51 184 Q96P65 3.19e-27 Pyroglutamylated RF-amide peptide receptor (AQ27) (G-protein coupled receptor 103) (Orexigenic neuropeptide QRFP receptor) (SP9155) Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:0016020 19891 XM_044323757.1 42 6 85 182 1 NA NA NA NA NA NA 19892 XM_044327931.1 5 0 12 2 54 NA NA NA NA NA NA 19893 XM_029348545.2 460 254 140 366 421 Q5ZLN0 2.26e-176 Leucine-rich repeat-containing protein 40 Gallus gallus (Chicken) cardiac muscle cell development [GO:0055013] GO:0003779; GO:0005856; GO:0030017; GO:0055013 19894 XR_006393460.1 5 188 50 104 112 NA NA NA NA NA NA 19895 XM_044323352.1 12 64 0 43 71 Q9H9B1 1.97e-150 Histone-lysine N-methyltransferase EHMT1 (EC 2.1.1.-) (EC 2.1.1.367) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a-like protein 1) (GLP) (GLP1) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Lysine N-methyltransferase 1D) Homo sapiens (Human) chromatin organization [GO:0006325]; DNA methylation [GO:0006306]; facultative heterochromatin formation [GO:0140718]; histone H3-K9 methylation [GO:0051567]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-lysine dimethylation [GO:0018027]; peptidyl-lysine monomethylation [GO:0018026]; positive regulation of cold-induced thermogenesis [GO:0120162]; regulation of embryonic development [GO:0045995]; regulation of histone H3-K9 methylation [GO:0051570] GO:0000122; GO:0000785; GO:0001222; GO:0002039; GO:0005634; GO:0005654; GO:0006306; GO:0006325; GO:0008168; GO:0008270; GO:0016279; GO:0016604; GO:0018024; GO:0018026; GO:0018027; GO:0045892; GO:0045995; GO:0046974; GO:0046976; GO:0051567; GO:0051570; GO:0070742; GO:0120162; GO:0140718; GO:0140947 19896 XM_044314275.1 0 0 10 0 0 NA NA NA NA NA NA 19897 XM_044324663.1 1 0 0 0 21 NA NA NA NA NA NA 19898 XM_044324351.1 1 1 17 1 23 NA NA NA NA NA NA 19899 XM_044327568.1 0 0 22 162 445 Q6DKN2 8.63e-32 Homeobox protein OTX2-B (xOTX2-B) (Orthodenticle 2-B) (Orthodenticle-A-like protein B) Xenopus laevis (African clawed frog) NA GO:0000981; GO:0003677; GO:0005634 19900 XM_044327609.1 21 12 0 71 3 NA NA NA NA NA NA 19901 XM_029345480.2 320 209 154 485 144 NA NA NA NA NA NA 19902 XR_006397215.1 976 652 581 1140 1115 Q5F3L4 0 Protein DENND6A (DENN domain-containing protein 6A) Gallus gallus (Chicken) NA GO:0005085; GO:0055037 19903 XM_029349406.2 4 24 11 0 8 NA NA NA NA NA NA 19904 XM_029355328.2 973 820 714 1289 1014 NA NA NA NA NA NA 19905 XM_029351273.2 0 0 0 104 296 P60764 3.91e-26 Ras-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3) Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; cell projection assembly [GO:0030031]; cerebral cortex GABAergic interneuron development [GO:0021894]; cortical cytoskeleton organization [GO:0030865]; establishment or maintenance of cell polarity [GO:0007163]; homeostasis of number of cells within a tissue [GO:0048873]; neuromuscular process [GO:0050905]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; postsynaptic actin cytoskeleton organization [GO:0098974]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell morphogenesis [GO:0022604]; regulation of cell shape [GO:0008360]; regulation of neuron maturation [GO:0014041]; small GTPase mediated signal transduction [GO:0007264]; synaptic transmission, GABAergic [GO:0051932]; Wnt signaling pathway [GO:0016055] GO:0003924; GO:0003925; GO:0005525; GO:0005829; GO:0005856; GO:0005886; GO:0005938; GO:0007015; GO:0007163; GO:0007264; GO:0008360; GO:0012505; GO:0014041; GO:0016055; GO:0019901; GO:0021894; GO:0022604; GO:0030027; GO:0030031; GO:0030036; GO:0030426; GO:0030865; GO:0031175; GO:0031410; GO:0031941; GO:0032956; GO:0033630; GO:0042995; GO:0043005; GO:0043025; GO:0048306; GO:0048471; GO:0048873; GO:0050885; GO:0050905; GO:0051932; GO:0071944; GO:0098974; GO:0098978; GO:1900026 19906 XM_029337163.2 5 0 0 0 16 NA NA NA NA NA NA 19907 XM_044327004.1 0 0 0 0 24 NA NA NA NA NA NA 19908 XR_006396575.1 51 0 17 0 38 Q8JFW4 2.85e-75 Probable inactive tRNA-specific adenosine deaminase-like protein 3 (tRNA-specific adenosine-34 deaminase subunit adat3) Danio rerio (Zebrafish) (Brachydanio rerio) tRNA processing [GO:0008033] GO:0003824; GO:0005634; GO:0005737; GO:0008033; GO:0046872 19909 XM_029333077.2 543 282 261 314 406 Q7T105 3.79e-49 Mesoderm induction early response protein 1 (Early response 1) (Er1) (Mi-er1) (Xmi-er1) Xenopus laevis (African clawed frog) chromatin remodeling [GO:0006338]; regulation of DNA-templated transcription [GO:0006355] GO:0003677; GO:0005634; GO:0006338; GO:0006355; GO:0017053 19910 XR_003822718.2 1 0 18 0 2 NA NA NA NA NA NA 19911 XM_029355423.2 1171 675 699 874 823 B3DIG4 0 NA NA NA NA 19912 XM_044317867.1 0 11 0 41 49 Q8CG08 4.55e-43 Collagen triple helix repeat-containing protein 1 Rattus norvegicus (Rat) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005581; GO:0005615; GO:0005737; GO:0016477; GO:0016528; GO:0017147; GO:0031012; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0090090; GO:0090103; GO:0090177 19913 XM_029341139.2 67 18 93 51 73 NA NA NA NA NA NA 19914 XM_044322015.1 135 36 89 73 25 NA NA NA NA NA NA 19915 XM_029335926.2 379 216 237 248 338 Q9JIA7 2.14e-66 Sphingosine kinase 2 (SK 2) (SPK 2) (EC 2.7.1.91) Mus musculus (Mouse) blood vessel development [GO:0001568]; brain development [GO:0007420]; cell population proliferation [GO:0008283]; cellular response to phorbol 13-acetate 12-myristate [GO:1904628]; female pregnancy [GO:0007565]; histone H2A-K5 acetylation [GO:0043977]; histone H2B-K12 acetylation [GO:0043980]; negative regulation of cell growth [GO:0030308]; negative regulation of histone deacetylase activity [GO:1901726]; negative regulation of histone deacetylation [GO:0031064]; phosphorylation [GO:0016310]; positive regulation of apoptotic process [GO:0043065]; positive regulation of calcium ion import [GO:0090280]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of histone H3-K9 acetylation [GO:2000617]; positive regulation of interleukin-13 production [GO:0032736]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of mast cell activation involved in immune response [GO:0033008]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of ATP biosynthetic process [GO:2001169]; regulation of cytochrome-c oxidase activity [GO:1904959]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of reactive oxygen species biosynthetic process [GO:1903426]; sphinganine-1-phosphate biosynthetic process [GO:0006669]; sphingolipid metabolic process [GO:0006665]; sphingosine biosynthetic process [GO:0046512]; sphingosine metabolic process [GO:0006670]; transcription initiation-coupled chromatin remodeling [GO:0045815] GO:0000786; GO:0001568; GO:0001727; GO:0002720; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005743; GO:0005765; GO:0005783; GO:0005829; GO:0005886; GO:0006665; GO:0006669; GO:0006670; GO:0007420; GO:0007565; GO:0008283; GO:0008284; GO:0008481; GO:0016020; GO:0016310; GO:0017050; GO:0030308; GO:0031064; GO:0032736; GO:0032755; GO:0032760; GO:0033008; GO:0038036; GO:0042393; GO:0043065; GO:0043122; GO:0043231; GO:0043306; GO:0043977; GO:0043980; GO:0045815; GO:0046512; GO:0090037; GO:0090280; GO:1901726; GO:1903426; GO:1904628; GO:1904959; GO:2000304; GO:2000617; GO:2001169 19916 XM_044307701.1 213 90 67 104 99 F1QCP6 5.67e-78 Tafazzin (Taz) (EC 2.3.1.-) Danio rerio (Zebrafish) (Brachydanio rerio) cardiolipin acyl-chain remodeling [GO:0035965]; cardiolipin metabolic process [GO:0032048]; heart development [GO:0007507]; heart looping [GO:0001947]; inner mitochondrial membrane organization [GO:0007007]; mitophagy [GO:0000423]; positive regulation of heart contraction [GO:0045823] GO:0000423; GO:0001947; GO:0005739; GO:0005741; GO:0005743; GO:0007007; GO:0007507; GO:0008374; GO:0031966; GO:0032048; GO:0035965; GO:0045823; GO:0047184 19917 XM_044318851.1 513 214 551 435 443 Q569T7 7.91e-53 Sodium-dependent glucose transporter 1 (Major facilitator superfamily domain-containing protein 4B) Xenopus laevis (African clawed frog) carbohydrate transport [GO:0008643]; sodium ion transport [GO:0006814] GO:0006814; GO:0008643; GO:0015293; GO:0016324 19918 XM_029350681.2 416 369 384 406 217 Q9I8C7 4.13e-84 Neuronal acetylcholine receptor subunit alpha-10 (Alpha 10 nAChR) (Nicotinic acetylcholine receptor subunit alpha-10) (NACHR alpha-10) Gallus gallus (Chicken) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; response to auditory stimulus [GO:0010996]; signal transduction [GO:0007165] GO:0004888; GO:0005231; GO:0005262; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0010996; GO:0022848; GO:0030594; GO:0034220; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051899; GO:1904315 19919 XM_044323394.1 1282 540 695 706 2352 NA NA NA NA NA NA 19920 XM_029332868.2 238 162 128 149 214 Q8K2J9 3.22e-73 BTB/POZ domain-containing protein 6 Mus musculus (Mouse) neurogenesis [GO:0022008] GO:0005829; GO:0022008 19921 XM_044306826.1 1338 1369 383 2431 1431 NA NA NA NA NA NA 19922 XM_044310632.1 13 9 0 14 17 P81274 3.24e-42 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 19923 XM_044310632.1 13 9 0 14 17 P81274 1.51e-33 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 19924 XM_044310632.1 13 9 0 14 17 P81274 1.47e-30 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 19925 XM_044310632.1 13 9 0 14 17 P81274 1.39e-26 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 19926 XM_044325688.1 5 0 3 3 15 NA NA NA NA NA NA 19927 XM_044310202.1 53 37 47 6 81 Q09575 9.64e-57 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 19928 XR_006392829.1 68 25 79 53 160 NA NA NA NA NA NA 19929 XM_044310351.1 20 0 6 14 41 NA NA NA NA NA NA 19930 XM_044319289.1 364 311 151 246 357 Q92540 3.52e-105 Nonsense-mediated mRNA decay factor SMG7 (SMG-7 homolog) (hSMG-7) Homo sapiens (Human) mRNA export from nucleus [GO:0006406]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of dephosphorylation [GO:0035303] GO:0000184; GO:0005634; GO:0005697; GO:0005737; GO:0005829; GO:0006406; GO:0035303; GO:0042162; GO:0045111; GO:0051721; GO:0070034 19931 XM_029341806.2 459 207 294 363 823 Q5R5N8 0 DIS3-like exonuclease 1 (EC 3.1.13.-) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0000175; GO:0000177; GO:0003723 19932 XM_044308392.1 0 23 0 38 0 NA NA NA NA NA NA 19933 XM_029356169.2 27 10 30 19 44 Q96A58 9.49e-36 Ras-related and estrogen-regulated growth inhibitor (EC 3.6.5.2) Homo sapiens (Human) negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; Ras protein signal transduction [GO:0007265]; response to hormone [GO:0009725]; small GTPase mediated signal transduction [GO:0007264] GO:0001650; GO:0003924; GO:0003925; GO:0005525; GO:0005634; GO:0005654; GO:0005829; GO:0005886; GO:0007264; GO:0007265; GO:0008285; GO:0009725; GO:0019003; GO:0030308; GO:0030331 19934 XR_006392154.1 6 19 2 7 24 NA NA NA NA NA NA 19935 XM_029330314.2 0 0 0 19 0 Q5ZLS8 5.59e-86 Integrator complex subunit 10 (Int10) Gallus gallus (Chicken) snRNA processing [GO:0016180] GO:0016180; GO:0032039 19936 XM_044322302.1 59 0 9 23 0 C6KFA3 8.59e-21 Adhesion G-protein coupled receptor G6 (G-protein coupled receptor 126) [Cleaved into: ADGRG6 N-terminal fragment (ADGRG6-NTF); ADGRG6 C-terminal fragment (ADGRG6-CTF)] Danio rerio (Zebrafish) (Brachydanio rerio) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cAMP-mediated signaling [GO:0019933]; cell surface receptor signaling pathway [GO:0007166]; ear development [GO:0043583]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; heart trabecula formation [GO:0060347]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; myelination of posterior lateral line nerve axons [GO:0048932]; ossification [GO:0001503]; peripheral nervous system myelin formation [GO:0032290]; regulation of sprouting angiogenesis [GO:1903670]; Schwann cell differentiation [GO:0014037]; semicircular canal fusion [GO:0060879] GO:0001503; GO:0004930; GO:0005518; GO:0005886; GO:0007005; GO:0007166; GO:0007186; GO:0007189; GO:0007507; GO:0014037; GO:0019933; GO:0022011; GO:0032290; GO:0042552; GO:0043236; GO:0043583; GO:0048932; GO:0050840; GO:0060347; GO:0060879; GO:1903670 19937 XM_044309254.1 16 1 26 8 33 NA NA NA NA NA NA 19938 XR_006394725.1 213 90 93 187 130 NA NA NA NA NA NA 19939 XM_029329536.2 682 942 524 756 458 NA NA NA NA NA NA 19940 XM_044322980.1 15 0 0 344 338 NA NA NA NA NA NA 19941 XM_044317583.1 36 2 125 6 157 NA NA NA NA NA NA 19942 XM_044327517.1 1070 631 453 600 642 NA NA NA NA NA NA 19943 XM_044316050.1 42 11 38 10 333 NA NA NA NA NA NA 19944 XM_029325274.2 19 0 0 0 6 NA NA NA NA NA NA 19945 XM_044308944.1 0 0 17 0 0 NA NA NA NA NA NA 19946 XM_029332006.2 1944 1311 1282 1702 3005 Q66I12 1.93e-88 PAT complex subunit CCDC47 (Coiled-coil domain-containing protein 47) Danio rerio (Zebrafish) (Brachydanio rerio) endoplasmic reticulum calcium ion homeostasis [GO:0032469]; protein insertion into ER membrane [GO:0045048] GO:0005509; GO:0005783; GO:0005789; GO:0030867; GO:0032469; GO:0043022; GO:0044183; GO:0045048 19947 XM_044320282.1 0 89 0 0 0 P07207 3.38e-88 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 19948 XM_044320282.1 0 89 0 0 0 P07207 9.19e-81 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 19949 XM_044320282.1 0 89 0 0 0 P07207 7e-74 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 19950 XM_044320282.1 0 89 0 0 0 P07207 3.62e-71 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 19951 XM_044320282.1 0 89 0 0 0 P07207 3.93e-65 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 19952 XM_044320282.1 0 89 0 0 0 P07207 3.35e-60 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 19953 XM_044320282.1 0 89 0 0 0 P07207 1.03e-56 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 19954 XM_044320282.1 0 89 0 0 0 P07207 2.52e-55 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 19955 XM_044320282.1 0 89 0 0 0 P07207 8.27e-55 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 19956 XM_044320282.1 0 89 0 0 0 P07207 6.29e-52 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 19957 XM_044320282.1 0 89 0 0 0 P07207 2.05e-45 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 19958 XM_044320506.1 1182 928 932 898 1196 Q7RTR2 3.91e-37 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 19959 XM_044320506.1 1182 928 932 898 1196 Q7RTR2 5.12e-33 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 19960 XM_044320506.1 1182 928 932 898 1196 Q7RTR2 3.73e-32 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 19961 XM_044320506.1 1182 928 932 898 1196 Q7RTR2 2.47e-31 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 19962 XM_044320506.1 1182 928 932 898 1196 Q7RTR2 1.33e-26 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 19963 XM_044311186.1 108 53 81 69 38 NA NA NA NA NA NA 19964 XM_029345077.2 162 161 143 358 147 NA NA NA NA NA NA 19965 XM_044327697.1 12 38 46 23 182 Q61554 4.94e-66 Fibrillin-1 [Cleaved into: Asprosin] Mus musculus (Mouse) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; kidney development [GO:0001822]; metanephros development [GO:0001656]; negative regulation of brown fat cell differentiation [GO:1903444]; negative regulation of insulin secretion [GO:0046676]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0001822; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0046676; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1903444; GO:1990314; GO:2001205 19966 XM_044327697.1 12 38 46 23 182 Q61554 3.11e-60 Fibrillin-1 [Cleaved into: Asprosin] Mus musculus (Mouse) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; kidney development [GO:0001822]; metanephros development [GO:0001656]; negative regulation of brown fat cell differentiation [GO:1903444]; negative regulation of insulin secretion [GO:0046676]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0001822; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0046676; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1903444; GO:1990314; GO:2001205 19967 XM_044327697.1 12 38 46 23 182 Q61554 1.44e-55 Fibrillin-1 [Cleaved into: Asprosin] Mus musculus (Mouse) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; kidney development [GO:0001822]; metanephros development [GO:0001656]; negative regulation of brown fat cell differentiation [GO:1903444]; negative regulation of insulin secretion [GO:0046676]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0001822; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0046676; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1903444; GO:1990314; GO:2001205 19968 XM_044327697.1 12 38 46 23 182 Q61554 4.41e-53 Fibrillin-1 [Cleaved into: Asprosin] Mus musculus (Mouse) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; kidney development [GO:0001822]; metanephros development [GO:0001656]; negative regulation of brown fat cell differentiation [GO:1903444]; negative regulation of insulin secretion [GO:0046676]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0001822; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0046676; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1903444; GO:1990314; GO:2001205 19969 XM_044327697.1 12 38 46 23 182 Q61554 5.42e-49 Fibrillin-1 [Cleaved into: Asprosin] Mus musculus (Mouse) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; kidney development [GO:0001822]; metanephros development [GO:0001656]; negative regulation of brown fat cell differentiation [GO:1903444]; negative regulation of insulin secretion [GO:0046676]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0001822; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0046676; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1903444; GO:1990314; GO:2001205 19970 XM_044327697.1 12 38 46 23 182 Q61554 7.69e-49 Fibrillin-1 [Cleaved into: Asprosin] Mus musculus (Mouse) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; kidney development [GO:0001822]; metanephros development [GO:0001656]; negative regulation of brown fat cell differentiation [GO:1903444]; negative regulation of insulin secretion [GO:0046676]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0001822; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0046676; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1903444; GO:1990314; GO:2001205 19971 XM_044327697.1 12 38 46 23 182 Q61554 2.38e-46 Fibrillin-1 [Cleaved into: Asprosin] Mus musculus (Mouse) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; kidney development [GO:0001822]; metanephros development [GO:0001656]; negative regulation of brown fat cell differentiation [GO:1903444]; negative regulation of insulin secretion [GO:0046676]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0001822; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0046676; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1903444; GO:1990314; GO:2001205 19972 XM_044327697.1 12 38 46 23 182 Q61554 3.02e-46 Fibrillin-1 [Cleaved into: Asprosin] Mus musculus (Mouse) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; kidney development [GO:0001822]; metanephros development [GO:0001656]; negative regulation of brown fat cell differentiation [GO:1903444]; negative regulation of insulin secretion [GO:0046676]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0001822; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0046676; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1903444; GO:1990314; GO:2001205 19973 XM_044327697.1 12 38 46 23 182 Q61554 5.3e-41 Fibrillin-1 [Cleaved into: Asprosin] Mus musculus (Mouse) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; kidney development [GO:0001822]; metanephros development [GO:0001656]; negative regulation of brown fat cell differentiation [GO:1903444]; negative regulation of insulin secretion [GO:0046676]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0001822; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0046676; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1903444; GO:1990314; GO:2001205 19974 XM_044327697.1 12 38 46 23 182 Q61554 1.18e-30 Fibrillin-1 [Cleaved into: Asprosin] Mus musculus (Mouse) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; kidney development [GO:0001822]; metanephros development [GO:0001656]; negative regulation of brown fat cell differentiation [GO:1903444]; negative regulation of insulin secretion [GO:0046676]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0001822; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0046676; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1903444; GO:1990314; GO:2001205 19975 XM_044327697.1 12 38 46 23 182 Q61554 9.45e-29 Fibrillin-1 [Cleaved into: Asprosin] Mus musculus (Mouse) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; kidney development [GO:0001822]; metanephros development [GO:0001656]; negative regulation of brown fat cell differentiation [GO:1903444]; negative regulation of insulin secretion [GO:0046676]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0001822; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0046676; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1903444; GO:1990314; GO:2001205 19976 XM_044327697.1 12 38 46 23 182 Q61554 4.44e-28 Fibrillin-1 [Cleaved into: Asprosin] Mus musculus (Mouse) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; kidney development [GO:0001822]; metanephros development [GO:0001656]; negative regulation of brown fat cell differentiation [GO:1903444]; negative regulation of insulin secretion [GO:0046676]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0001822; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0046676; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1903444; GO:1990314; GO:2001205 19977 XM_029339213.2 2078 1296 1503 3123 980 NA NA NA NA NA NA 19978 XR_006393986.1 136 0 69 0 0 Q8BH74 0 Nuclear pore complex protein Nup107 (107 kDa nucleoporin) (Nucleoporin Nup107) Mus musculus (Mouse) female gonad development [GO:0008585]; mRNA export from nucleus [GO:0006406]; nephron development [GO:0072006]; nuclear pore complex assembly [GO:0051292]; nucleocytoplasmic transport [GO:0006913]; post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000973]; protein import into nucleus [GO:0006606] GO:0000776; GO:0000973; GO:0005635; GO:0005643; GO:0006406; GO:0006606; GO:0006913; GO:0008585; GO:0017056; GO:0031080; GO:0031965; GO:0034399; GO:0051292; GO:0072006 19979 XR_006398091.1 225 207 134 135 278 NA NA NA NA NA NA 19980 XM_044310491.1 309 969 344 46 91 NA NA NA NA NA NA 19981 XR_006395967.1 138 76 35 362 125 NA NA NA NA NA NA 19982 XM_029341162.2 43 86 16 58 79 NA NA NA NA NA NA 19983 XM_029338845.2 351 340 349 453 422 Q8VBT2 7.84e-96 L-serine dehydratase/L-threonine deaminase (SDH) (EC 4.3.1.17) (L-serine deaminase) (L-threonine dehydratase) (TDH) (EC 4.3.1.19) Mus musculus (Mouse) gluconeogenesis [GO:0006094]; isoleucine biosynthetic process [GO:0009097]; L-serine catabolic process [GO:0006565]; lipid metabolic process [GO:0006629]; protein-containing complex assembly [GO:0065003]; pyruvate biosynthetic process [GO:0042866]; threonine catabolic process [GO:0006567] GO:0003941; GO:0004794; GO:0005739; GO:0005829; GO:0006094; GO:0006565; GO:0006567; GO:0006629; GO:0009097; GO:0030170; GO:0042803; GO:0042866; GO:0065003 19984 XM_029337341.2 770 184 301 430 268 P53668 1.45e-146 LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1) (KIZ-1) Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; axon extension [GO:0048675]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of axon extension [GO:0045773]; positive regulation of stress fiber assembly [GO:0051496]; protein phosphorylation [GO:0006468]; stress fiber assembly [GO:0043149] GO:0001673; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005925; GO:0006468; GO:0016020; GO:0016607; GO:0030027; GO:0030036; GO:0031072; GO:0032233; GO:0043005; GO:0043149; GO:0044295; GO:0045773; GO:0046872; GO:0048471; GO:0048675; GO:0051444; GO:0051496; GO:0106310 19985 XM_044312229.1 0 1 15 32 85 NA NA NA NA NA NA 19986 XM_044311232.1 5 0 0 5 13 NA NA NA NA NA NA 19987 XM_044318957.1 72 66 22 209 100 O73853 1.67e-96 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Ictalurus punctatus (Channel catfish) (Silurus punctatus) steroid biosynthetic process [GO:0006694] GO:0004508; GO:0005506; GO:0006694; GO:0016020; GO:0020037; GO:0047442 19988 XR_003825612.2 205 193 119 201 151 NA NA NA NA NA NA 19989 XM_044324613.1 0 36 9 3 25 NA NA NA NA NA NA 19990 XM_029328634.2 1612 1251 1176 1994 1193 NA NA NA NA NA NA 19991 XM_044323399.1 0 0 32 0 0 NA NA NA NA NA NA 19992 XM_044320634.1 31 17 335 3 134 NA NA NA NA NA NA 19993 XR_006396709.1 10 2 1 3 25 NA NA NA NA NA NA 19994 XM_029335842.2 8367 9162 6202 8209 8532 P00514 0 cAMP-dependent protein kinase type I-alpha regulatory subunit [Cleaved into: cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed] Bos taurus (Bovine) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cardiac muscle cell proliferation [GO:0060038]; mesoderm formation [GO:0001707]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of cAMP-dependent protein kinase activity [GO:2000480]; negative regulation of gene expression [GO:0010629]; positive regulation of insulin secretion [GO:0032024]; sarcomere organization [GO:0045214] GO:0001707; GO:0001772; GO:0004862; GO:0005737; GO:0005771; GO:0005813; GO:0005930; GO:0005952; GO:0007189; GO:0010629; GO:0019904; GO:0030552; GO:0031588; GO:0031594; GO:0031625; GO:0032024; GO:0034236; GO:0042802; GO:0044853; GO:0045214; GO:0046007; GO:0060038; GO:0097224; GO:0098978; GO:2000480 19995 XM_044307092.1 23 28 0 0 0 Q8CEE7 1.11e-70 Retinol dehydrogenase 13 (EC 1.1.1.300) Mus musculus (Mouse) eye photoreceptor cell development [GO:0042462]; response to high light intensity [GO:0009644]; retina layer formation [GO:0010842]; retinal metabolic process [GO:0042574] GO:0005739; GO:0005743; GO:0009644; GO:0010842; GO:0042462; GO:0042574; GO:0052650 19996 XM_044317999.1 602 423 652 623 2838 P21328 1.39e-40 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 19997 XM_044324811.1 141 62 49 338 198 NA NA NA NA NA NA 19998 XM_029338611.2 308 161 186 402 325 A0LJ16 2.18e-73 Phosphonoacetaldehyde hydrolase-like protein Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) organic phosphonate catabolic process [GO:0019700] GO:0000287; GO:0019700; GO:0050194 19999 XM_029332944.2 670 701 233 955 1081 Q60928 3.88e-155 Glutathione hydrolase 1 proenzyme (EC 3.4.19.13) (Gamma-glutamyltransferase 1) (Gamma-glutamyltranspeptidase 1) (GGT 1) (EC 2.3.2.2) (Leukotriene-C4 hydrolase) (EC 3.4.19.14) (CD antigen CD224) [Cleaved into: Glutathione hydrolase 1 heavy chain; Glutathione hydrolase 1 light chain] Mus musculus (Mouse) aging [GO:0007568]; cellular response to oxidative stress [GO:0034599]; cysteine biosynthetic process [GO:0019344]; glutamate metabolic process [GO:0006536]; glutathione biosynthetic process [GO:0006750]; glutathione catabolic process [GO:0006751]; glutathione metabolic process [GO:0006749]; hepatoblast differentiation [GO:0061017]; hepatocyte differentiation [GO:0070365]; liver regeneration [GO:0097421]; peptide modification [GO:0031179]; regulation of immune system process [GO:0002682]; regulation of inflammatory response [GO:0050727]; response to alcohol [GO:0097305]; response to estradiol [GO:0032355]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]; spermatogenesis [GO:0007283]; zymogen activation [GO:0031638] GO:0000048; GO:0002682; GO:0002951; GO:0005615; GO:0005783; GO:0005886; GO:0006536; GO:0006749; GO:0006750; GO:0006751; GO:0007283; GO:0007568; GO:0016755; GO:0019344; GO:0031179; GO:0031638; GO:0031982; GO:0032355; GO:0032496; GO:0034599; GO:0034612; GO:0036374; GO:0048471; GO:0050727; GO:0061017; GO:0070365; GO:0097305; GO:0097421; GO:0102953; GO:0103068 20000 XM_044313275.1 2400 1496 1375 2054 2241 Q60629 5.61e-156 Ephrin type-A receptor 5 (EC 2.7.10.1) (Brain-specific kinase) (CEK-7) (EPH homology kinase 1) (EHK-1) Mus musculus (Mouse) axon guidance [GO:0007411]; cAMP-mediated signaling [GO:0019933]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to forskolin [GO:1904322]; dendritic spine morphogenesis [GO:0060997]; ephrin receptor signaling pathway [GO:0048013]; hippocampus development [GO:0021766]; negative regulation of cell adhesion [GO:0007162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of kinase activity [GO:0033674]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of GTPase activity [GO:0043087]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0004714; GO:0005003; GO:0005004; GO:0005005; GO:0005524; GO:0005791; GO:0005886; GO:0005912; GO:0007162; GO:0007169; GO:0007411; GO:0009897; GO:0019838; GO:0019933; GO:0021766; GO:0030424; GO:0030425; GO:0032793; GO:0032956; GO:0033674; GO:0043005; GO:0043025; GO:0043087; GO:0043235; GO:0048013; GO:0048471; GO:0060997; GO:0061178; GO:0071372; GO:0071944; GO:1904322 20001 XM_044319879.1 35 21 3 3 20 NA NA NA NA NA NA 20002 XR_006393623.1 879 1561 918 812 860 NA NA NA NA NA NA 20003 XM_029323465.2 0 0 0 0 7 NA NA NA NA NA NA 20004 XR_006392338.1 383 450 392 251 145 NA NA NA NA NA NA 20005 XM_044328452.1 18 0 2 0 1 Q96AY4 1.74e-53 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20006 XM_044328452.1 18 0 2 0 1 Q96AY4 3.21e-50 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20007 XM_044328452.1 18 0 2 0 1 Q96AY4 3.88e-49 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20008 XM_044328452.1 18 0 2 0 1 Q96AY4 2.01e-48 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20009 XM_044328452.1 18 0 2 0 1 Q96AY4 5.16e-46 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20010 XM_044328452.1 18 0 2 0 1 Q96AY4 9.53e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20011 XM_044328452.1 18 0 2 0 1 Q96AY4 2.06e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20012 XM_044328452.1 18 0 2 0 1 Q96AY4 1.44e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20013 XM_044328452.1 18 0 2 0 1 Q96AY4 7.2e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20014 XM_044328452.1 18 0 2 0 1 Q96AY4 4.31e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20015 XM_044328452.1 18 0 2 0 1 Q96AY4 6.64e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20016 XM_044328452.1 18 0 2 0 1 Q96AY4 2.31e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20017 XM_044328452.1 18 0 2 0 1 Q96AY4 2.9e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20018 XM_044328452.1 18 0 2 0 1 Q96AY4 1.81e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20019 XM_044328452.1 18 0 2 0 1 Q96AY4 8.98e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20020 XM_044328452.1 18 0 2 0 1 Q96AY4 3.55e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20021 XR_003828498.2 0 0 4 12 37 NA NA NA NA NA NA 20022 XM_044325580.1 43 49 24 0 0 NA NA NA NA NA NA 20023 XM_029333479.2 11603 8580 5338 23855 33822 NA NA NA NA NA NA 20024 XM_029358298.2 420 0 298 56 35 Q9QYS2 0 Metabotropic glutamate receptor 3 (mGluR3) Mus musculus (Mouse) G protein-coupled glutamate receptor signaling pathway [GO:0007216]; gene expression [GO:0010467]; modulation of chemical synaptic transmission [GO:0050804]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; regulation of sensory perception of pain [GO:0051930]; regulation of synaptic transmission, glutamatergic [GO:0051966]; sensory perception of pain [GO:0019233]; synaptic transmission, glutamatergic [GO:0035249] GO:0001640; GO:0001641; GO:0005246; GO:0005886; GO:0007216; GO:0010467; GO:0014069; GO:0019233; GO:0030424; GO:0035249; GO:0042734; GO:0043005; GO:0043197; GO:0045211; GO:0048786; GO:0050804; GO:0051930; GO:0051966; GO:0097110; GO:0097449; GO:0098978; GO:0099170 20025 XM_044320162.1 1710 1065 1085 1579 736 Q9CWB7 2.83e-23 Glutaredoxin-like protein C5orf63 homolog Mus musculus (Mouse) NA GO:0005739 20026 XM_029337278.2 9 0 4 31 14 A6NFN3 6.57e-36 RNA binding protein fox-1 homolog 3 (Fox-1 homolog C) (Neuronal nuclei antigen) (NeuN antigen) Homo sapiens (Human) mRNA processing [GO:0006397]; nervous system development [GO:0007399]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380] GO:0000381; GO:0003729; GO:0005634; GO:0005737; GO:0006397; GO:0007399; GO:0008380 20027 XR_006397798.1 0 0 64 0 0 NA NA NA NA NA NA 20028 XM_044312423.1 836 330 690 845 1169 NA NA NA NA NA NA 20029 XM_044326574.1 0 0 24 210 107 NA NA NA NA NA NA 20030 XR_003826911.2 212 210 191 199 190 NA NA NA NA NA NA 20031 XM_044319810.1 0 75 0 0 0 P97292 4.16e-21 Histamine H2 receptor (H2R) (HH2R) (Gastric receptor I) Mus musculus (Mouse) chemical synaptic transmission [GO:0007268]; digestive tract development [GO:0048565]; epithelial cell morphogenesis [GO:0003382]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; gastric acid secretion [GO:0001696]; gastrin-induced gastric acid secretion [GO:0001698]; gland development [GO:0048732]; histamine-induced gastric acid secretion [GO:0001697]; memory [GO:0007613]; negative regulation of arachidonic acid secretion [GO:1900139]; positive regulation of vasoconstriction [GO:0045907]; regulation of synaptic plasticity [GO:0048167]; toxin transport [GO:1901998]; visual learning [GO:0008542] GO:0001696; GO:0001697; GO:0001698; GO:0003382; GO:0004969; GO:0004993; GO:0005886; GO:0007187; GO:0007268; GO:0007613; GO:0008542; GO:0016020; GO:0030425; GO:0030594; GO:0045202; GO:0045907; GO:0048167; GO:0048565; GO:0048732; GO:1900139; GO:1901363; GO:1901998 20032 XM_044316987.1 22 12 7 23 9 NA NA NA NA NA NA 20033 XM_029351459.2 66 47 18 49 80 NA NA NA NA NA NA 20034 XM_029326182.2 13 9 68 25 314 Q99315 1.35e-57 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 20035 XM_029332149.2 7457 1292 961 7998 2707 D9IQ16 0 Galaxin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 20036 XM_044321429.1 2562 661 249223 777 422 NA NA NA NA NA NA 20037 XM_044317276.1 0 0 12 0 0 NA NA NA NA NA NA 20038 XM_044327856.1 8 10 62 40 172 O13018 7.41e-43 Vertebrate ancient opsin Salmo salar (Atlantic salmon) phototransduction, visible light [GO:0007603] GO:0004930; GO:0007603; GO:0009881; GO:0016020 20039 XM_029324390.2 272 381 369 472 399 Q9NZ63 2.26e-63 Splicing factor C9orf78 (Hepatocellular carcinoma-associated antigen 59) Homo sapiens (Human) chromosome segregation [GO:0007059]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; regulation of homologous chromosome segregation [GO:0060629] GO:0000398; GO:0000775; GO:0005634; GO:0005654; GO:0005681; GO:0005829; GO:0007059; GO:0030623; GO:0045292; GO:0060629 20040 XM_029333010.2 185 48 65 37 30 NA NA NA NA NA NA 20041 XR_006392555.1 643 350 157 118 535 NA NA NA NA NA NA 20042 XM_044312650.1 41 18 20 15 70 NA NA NA NA NA NA 20043 XM_029338796.2 6670 2815 3474 6424 5497 P55214 2.68e-66 Caspase-7 (CASP-7) (EC 3.4.22.60) (Apoptotic protease Mch-3) (ICE-like apoptotic protease 3) (ICE-LAP3) (SREBP cleavage activity 2) (SCA-2) [Cleaved into: Caspase-7 subunit p20; Caspase-7 subunit p11] Mesocricetus auratus (Golden hamster) defense response to bacterium [GO:0042742]; intracellular signal transduction [GO:0035556]; lymphocyte apoptotic process [GO:0070227]; positive regulation of plasma membrane repair [GO:1905686]; proteolysis [GO:0006508] GO:0003723; GO:0004190; GO:0005615; GO:0005634; GO:0005737; GO:0005829; GO:0006508; GO:0035556; GO:0042742; GO:0070227; GO:0097153; GO:1905686 20044 XR_003824790.1 411 399 418 386 531 NA NA NA NA NA NA 20045 XM_044319867.1 37 31 11 69 92 NA NA NA NA NA NA 20046 XM_044312890.1 12 6 0 5 2 NA NA NA NA NA NA 20047 XM_029349410.2 213 67 90 89 40 NA NA NA NA NA NA 20048 XR_003828584.2 1473 2436 427 990 949 NA NA NA NA NA NA 20049 XR_006393887.1 45 0 8 0 69 NA NA NA NA NA NA 20050 XM_044307477.1 173 192 80 243 92 Q53HC5 7.2e-36 Kelch-like protein 26 Homo sapiens (Human) NA NA 20051 XM_029334291.2 968 107 49 750 79 NA NA NA NA NA NA 20052 XM_029351770.2 0 0 0 0 10 P47863 1.96e-23 Aquaporin-4 (AQP-4) (Mercurial-insensitive water channel) (MIWC) (WCH4) Rattus norvegicus (Rat) carbon dioxide transport [GO:0015670]; cell-cell adhesion [GO:0098609]; cellular response to estradiol stimulus [GO:0071392]; cellular response to glucose stimulus [GO:0071333]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to type II interferon [GO:0071346]; cellular water homeostasis [GO:0009992]; cerebrospinal fluid circulation [GO:0090660]; cerebrospinal fluid secretion [GO:0033326]; establishment of localization in cell [GO:0051649]; female pregnancy [GO:0007565]; hyperosmotic salinity response [GO:0042538]; multicellular organismal water homeostasis [GO:0050891]; negative regulation of cell adhesion molecule production [GO:0060354]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-6 production [GO:0032715]; protein homotetramerization [GO:0051289]; regulation of vascular endothelial growth factor production [GO:0010574]; renal water absorption [GO:0070295]; response to glucocorticoid [GO:0051384]; response to radiation [GO:0009314]; sensory perception of sound [GO:0007605]; water homeostasis [GO:0030104]; water transport [GO:0006833] GO:0005576; GO:0005737; GO:0005886; GO:0005911; GO:0006833; GO:0007565; GO:0007605; GO:0009314; GO:0009897; GO:0009925; GO:0009992; GO:0010008; GO:0010574; GO:0015250; GO:0015670; GO:0016020; GO:0016323; GO:0030104; GO:0030315; GO:0031253; GO:0032691; GO:0032715; GO:0032991; GO:0033326; GO:0042383; GO:0042538; GO:0042802; GO:0050891; GO:0051289; GO:0051384; GO:0051649; GO:0060354; GO:0070295; GO:0071333; GO:0071346; GO:0071347; GO:0071354; GO:0071392; GO:0090660; GO:0097450; GO:0098609 20053 XR_006392239.1 396 213 151 141 161 NA NA NA NA NA NA 20054 XR_003824167.2 60 370 18 79 264 NA NA NA NA NA NA 20055 XR_006396112.1 0 0 27 139 0 Q99570 6.74e-37 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 20056 XR_006396112.1 0 0 27 139 0 Q99570 6.74e-37 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 20057 XR_006396112.1 0 0 27 139 0 Q99570 7.84e-31 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 20058 XR_006396112.1 0 0 27 139 0 Q99570 7.84e-31 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 20059 XR_006396112.1 0 0 27 139 0 Q99570 7.84e-31 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 20060 XM_044328423.1 244 68 183 358 183 NA NA NA NA NA NA 20061 XM_029334689.2 1624 1588 1125 2068 2385 Q9W6X3 4.87e-35 10 kDa heat shock protein, mitochondrial (Hsp10) (10 kDa chaperonin) (Chaperonin 10) (CPN10) Oryzias latipes (Japanese rice fish) (Japanese killifish) chaperone cofactor-dependent protein refolding [GO:0051085] GO:0005524; GO:0005759; GO:0046872; GO:0051082; GO:0051085; GO:0051087; GO:0140662 20062 XM_029345823.2 942 565 480 702 819 Q08D69 4.81e-119 Mediator of RNA polymerase II transcription subunit 16 (Mediator complex subunit 16) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0016592 20063 XM_029351200.2 156 120 94 173 128 P22574 7.65e-26 Homeobox protein Hox-B4a (Hox-B4) (Homeobox protein Zf-13) Danio rerio (Zebrafish) (Brachydanio rerio) anterior/posterior pattern specification [GO:0009952]; embryonic skeletal system morphogenesis [GO:0048704]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0009952; GO:0048704 20064 XR_003823927.2 0 2 17 0 0 NA NA NA NA NA NA 20065 XM_029340171.2 125 64 3 197 36 NA NA NA NA NA NA 20066 XM_044319746.1 48 4 11 35 4 NA NA NA NA NA NA 20067 XR_006392891.1 41 2 25 5 151 NA NA NA NA NA NA 20068 XM_029335156.2 854 487 411 551 482 Q8N0W5 2.4e-36 IQ domain-containing protein K Homo sapiens (Human) NA NA 20069 XM_029335781.2 1014 711 629 789 706 Q96EX2 2.65e-73 RING finger and transmembrane domain-containing protein 2 (Transmembrane protein 118) Homo sapiens (Human) positive regulation of ERAD pathway [GO:1904294] GO:0016020; GO:0046872; GO:0061630; GO:1904294 20070 XM_029330428.2 0 0 0 3 6 NA NA NA NA NA NA 20071 XM_029338166.2 509 130 0 391 927 O57472 3.1e-100 Chordin (Protein chordino) Danio rerio (Zebrafish) (Brachydanio rerio) anterior/posterior axis specification [GO:0009948]; caudal fin morphogenesis [GO:0035143]; determination of heart left/right asymmetry [GO:0061371]; determination of left/right symmetry [GO:0007368]; determination of ventral identity [GO:0048264]; dorsal convergence [GO:0060030]; dorsal/ventral pattern formation [GO:0009953]; embryonic heart tube morphogenesis [GO:0003143]; embryonic hemopoiesis [GO:0035162]; heart looping [GO:0001947]; Kupffer's vesicle development [GO:0070121]; negative regulation of BMP signaling pathway [GO:0030514]; otic placode formation [GO:0043049]; regulation of BMP signaling pathway involved in heart jogging [GO:2000223]; somitogenesis [GO:0001756]; specification of animal organ position [GO:0010159] GO:0001756; GO:0001947; GO:0003143; GO:0005615; GO:0007368; GO:0009948; GO:0009953; GO:0010159; GO:0030514; GO:0035143; GO:0035162; GO:0036122; GO:0043049; GO:0048264; GO:0060030; GO:0061371; GO:0070121; GO:2000223 20072 XM_029324529.2 51 90 46 78 27 NA NA NA NA NA NA 20073 XM_029354154.2 39 0 0 69 30 Q6DHN0 3.8e-31 Transmembrane protein 53 Danio rerio (Zebrafish) (Brachydanio rerio) negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of ossification [GO:0030279]; negative regulation of osteoblast differentiation [GO:0045668]; regulation of nucleocytoplasmic transport [GO:0046822] GO:0005640; GO:0030279; GO:0030514; GO:0031965; GO:0045668; GO:0046822 20074 XM_029347634.2 3227 3642 2760 5741 5842 P08199 1.06e-26 Nucleolin (Protein C23) Mesocricetus auratus (Golden hamster) NA GO:0003723; GO:0005730; GO:0005737; GO:0042162; GO:1990904 20075 XM_044322339.1 16 77 137 116 268 P46023 5.5e-93 G-protein coupled receptor GRL101 Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004930; GO:0005886 20076 XM_029328518.2 1246 861 1045 1508 1720 Q8WTS1 4.48e-115 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 (EC 2.3.1.51) (Abhydrolase domain-containing protein 5) (Lipid droplet-binding protein CGI-58) Homo sapiens (Human) cell differentiation [GO:0030154]; fatty acid metabolic process [GO:0006631]; lipid homeostasis [GO:0055088]; negative regulation of sequestering of triglyceride [GO:0010891]; phosphatidic acid biosynthetic process [GO:0006654]; positive regulation of lipoprotein lipase activity [GO:0051006]; positive regulation of triglyceride catabolic process [GO:0010898] GO:0003841; GO:0005654; GO:0005739; GO:0005811; GO:0005829; GO:0006631; GO:0006654; GO:0010891; GO:0010898; GO:0030154; GO:0042171; GO:0043231; GO:0051006; GO:0055088 20077 XR_006392335.1 210 143 51 405 469 NA NA NA NA NA NA 20078 XM_044322047.1 41 0 0 0 3 NA NA NA NA NA NA 20079 XM_029334032.2 17 60 13 59 42 NA NA NA NA NA NA 20080 XM_044325656.1 86 70 112 43 558 NA NA NA NA NA NA 20081 XM_029357332.2 89 0 60 40 158 Q05941 1.27e-74 Neuronal acetylcholine receptor subunit alpha-7 Rattus norvegicus (Rat) acetylcholine receptor signaling pathway [GO:0095500]; associative learning [GO:0008306]; B cell activation [GO:0042113]; behavioral response to ethanol [GO:0048149]; behavioral response to nicotine [GO:0035095]; calcium ion transport [GO:0006816]; cation transmembrane transport [GO:0098655]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; cognition [GO:0050890]; dendrite arborization [GO:0140059]; dendritic spine organization [GO:0097061]; dopamine biosynthetic process [GO:0042416]; endocytosis [GO:0006897]; establishment of localization in cell [GO:0051649]; excitatory postsynaptic potential [GO:0060079]; flagellated sperm motility [GO:0030317]; generation of ovulation cycle rhythm [GO:0060112]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; learning or memory [GO:0007611]; membrane depolarization [GO:0051899]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; modulation of excitatory postsynaptic potential [GO:0098815]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of tumor necrosis factor production [GO:0032720]; nervous system process [GO:0050877]; neuronal action potential [GO:0019228]; ovulation cycle [GO:0042698]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of CoA-transferase activity [GO:1905920]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure [GO:0001988]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of amyloid fibril formation [GO:1905906]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of inflammatory response [GO:0050727]; regulation of membrane potential [GO:0042391]; regulation of neuron death [GO:1901214]; regulation of nitric oxide metabolic process [GO:0080164]; regulation of norepinephrine secretion [GO:0014061]; regulation of response to drug [GO:2001023]; regulation of synaptic transmission, dopaminergic [GO:0032225]; response to acetylcholine [GO:1905144]; response to amyloid-beta [GO:1904645]; response to carbamate [GO:0046681]; response to cold [GO:0009409]; response to ethanol [GO:0045471]; response to food [GO:0032094]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; sensory processing [GO:0050893]; signal transduction [GO:0007165]; synapse organization [GO:0050808]; synaptic transmission, cholinergic [GO:0007271]; T cell activation [GO:0042110] GO:0001540; GO:0001666; GO:0001933; GO:0001934; GO:0001988; GO:0005216; GO:0005231; GO:0005737; GO:0005886; GO:0005892; GO:0006811; GO:0006816; GO:0006874; GO:0006897; GO:0007165; GO:0007268; GO:0007271; GO:0007611; GO:0007613; GO:0008179; GO:0008284; GO:0008306; GO:0009409; GO:0009897; GO:0010628; GO:0014061; GO:0014069; GO:0015464; GO:0015643; GO:0016020; GO:0016324; GO:0017081; GO:0019228; GO:0019901; GO:0022848; GO:0030317; GO:0030424; GO:0030425; GO:0030426; GO:0030594; GO:0030673; GO:0032094; GO:0032225; GO:0032279; GO:0032691; GO:0032715; GO:0032720; GO:0033138; GO:0034220; GO:0035094; GO:0035095; GO:0042110; GO:0042113; GO:0042166; GO:0042391; GO:0042416; GO:0042698; GO:0042734; GO:0042803; GO:0043005; GO:0043025; GO:0043197; GO:0043198; GO:0043410; GO:0044853; GO:0045121; GO:0045202; GO:0045211; GO:0045471; GO:0045766; GO:0046681; GO:0048149; GO:0050727; GO:0050728; GO:0050804; GO:0050808; GO:0050877; GO:0050890; GO:0050893; GO:0051117; GO:0051247; GO:0051649; GO:0051899; GO:0060079; GO:0060112; GO:0070373; GO:0070374; GO:0080164; GO:0095500; GO:0097061; GO:0097110; GO:0098655; GO:0098690; GO:0098815; GO:0098897; GO:0098981; GO:0099171; GO:0099634; GO:0140059; GO:1900273; GO:1901214; GO:1902004; GO:1902430; GO:1902991; GO:1904315; GO:1904645; GO:1905144; GO:1905906; GO:1905920; GO:2000463; GO:2001023 20082 XM_044313063.1 6 8 3 4 3 Q96AY4 1.15e-100 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20083 XM_044313063.1 6 8 3 4 3 Q96AY4 9.05e-97 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20084 XM_044313063.1 6 8 3 4 3 Q96AY4 9.3e-91 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20085 XM_044313063.1 6 8 3 4 3 Q96AY4 2.39e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20086 XR_006396843.1 23 0 1 4 14 NA NA NA NA NA NA 20087 XM_029335408.2 433 314 266 318 337 NA NA NA NA NA NA 20088 XM_029338842.2 282 130 126 328 297 Q6PBD4 3.71e-25 Transcription factor HES-4 (Hairy and enhancer of split 4) (Protein hairy-2) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) floor plate development [GO:0033504]; lens development in camera-type eye [GO:0002088]; muscle organ development [GO:0007517]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of neurogenesis [GO:0050768]; negative regulation of skeletal muscle tissue development [GO:0048642]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural crest formation [GO:0014029]; Notch signaling pathway [GO:0007219]; prechordal plate formation [GO:0021501] GO:0000122; GO:0002088; GO:0005634; GO:0007219; GO:0007517; GO:0014029; GO:0021501; GO:0033504; GO:0043066; GO:0043565; GO:0045892; GO:0046982; GO:0048642; GO:0050768 20089 XR_006394983.1 0 15 0 8 0 NA NA NA NA NA NA 20090 XM_029324683.2 1735 1346 876 1392 1230 O46470 8.91e-172 Regulator of G-protein signaling 7 (RGS7) Bos taurus (Bovine) G protein-coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; regulation of G protein-coupled receptor signaling pathway [GO:0008277] GO:0005096; GO:0005737; GO:0005829; GO:0005886; GO:0007186; GO:0008277; GO:0009968; GO:0031681; GO:0035556; GO:0043005; GO:0043547 20091 XR_006392010.1 0 9 0 0 0 NA NA NA NA NA NA 20092 XM_029326751.2 45 78 85 0 111 P0CT40 4.42e-83 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 20093 XM_029350734.2 1418 1084 943 696 651 Q6DFC8 6.84e-38 Zinc finger protein 395 Xenopus laevis (African clawed frog) NA GO:0003677; GO:0005634; GO:0005737; GO:0046872 20094 XR_006393071.1 41 2 25 5 151 NA NA NA NA NA NA 20095 XR_006396519.1 17 17 38 9 26 NA NA NA NA NA NA 20096 XM_044315249.1 13 1 12 7 142 NA NA NA NA NA NA 20097 XR_006393099.1 127 56 37 111 50 NA NA NA NA NA NA 20098 XM_044319208.1 20 0 0 14 2 NA NA NA NA NA NA 20099 XM_044311164.1 63 14 24 15 75 NA NA NA NA NA NA 20100 XM_029335666.2 1054 286 538 726 1481 F1MA98 0 Nucleoprotein TPR (Megator) (NPC-associated intranuclear protein) (Translocated promoter region protein) Rattus norvegicus (Rat) cell division [GO:0051301]; cellular response to heat [GO:0034605]; cellular response to interferon-alpha [GO:0035457]; mitotic spindle assembly checkpoint signaling [GO:0007094]; mRNA export from nucleus [GO:0006406]; mRNA export from nucleus in response to heat stress [GO:0031990]; negative regulation of RNA export from nucleus [GO:0046832]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of translational initiation [GO:0045947]; nuclear pore organization [GO:0006999]; positive regulation of heterochromatin formation [GO:0031453]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; regulation of mitotic sister chromatid separation [GO:0010965]; regulation of mitotic spindle assembly [GO:1901673]; regulation of protein localization [GO:0032880]; response to epidermal growth factor [GO:0070849]; RNA export from nucleus [GO:0006405]; RNA import into nucleus [GO:0006404] GO:0000122; GO:0000776; GO:0003682; GO:0003729; GO:0005634; GO:0005635; GO:0005643; GO:0005737; GO:0005868; GO:0006404; GO:0006405; GO:0006406; GO:0006606; GO:0006611; GO:0006999; GO:0007094; GO:0010965; GO:0015631; GO:0017056; GO:0019898; GO:0031072; GO:0031453; GO:0031965; GO:0031990; GO:0032880; GO:0034399; GO:0034605; GO:0035457; GO:0042307; GO:0042405; GO:0042803; GO:0044615; GO:0045947; GO:0046827; GO:0046832; GO:0051019; GO:0051301; GO:0070840; GO:0070849; GO:0072686; GO:0090267; GO:0090316; GO:1901673 20101 XM_044318825.1 2929 1031 747 2139 1089 Q6ZW49 1.83e-110 PAX-interacting protein 1 (PAX transactivation activation domain-interacting protein) Homo sapiens (Human) adipose tissue development [GO:0060612]; chorion development [GO:0060717]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; endothelial cell migration [GO:0043542]; histone H3-K4 methylation [GO:0051568]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of isotype switching [GO:0045830]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of response to DNA damage stimulus [GO:2001022]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; regulation of cell cycle G2/M phase transition [GO:1902749]; response to ionizing radiation [GO:0010212]; vasculogenesis [GO:0001570] GO:0001570; GO:0005634; GO:0005654; GO:0005694; GO:0006281; GO:0006310; GO:0010212; GO:0016363; GO:0030330; GO:0031398; GO:0035097; GO:0043433; GO:0043542; GO:0044666; GO:0045830; GO:0048304; GO:0051568; GO:0051571; GO:0060261; GO:0060612; GO:0060717; GO:1902749; GO:2001022 20102 XM_044318825.1 2929 1031 747 2139 1089 Q6ZW49 4.95e-43 PAX-interacting protein 1 (PAX transactivation activation domain-interacting protein) Homo sapiens (Human) adipose tissue development [GO:0060612]; chorion development [GO:0060717]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; endothelial cell migration [GO:0043542]; histone H3-K4 methylation [GO:0051568]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of isotype switching [GO:0045830]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of response to DNA damage stimulus [GO:2001022]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; regulation of cell cycle G2/M phase transition [GO:1902749]; response to ionizing radiation [GO:0010212]; vasculogenesis [GO:0001570] GO:0001570; GO:0005634; GO:0005654; GO:0005694; GO:0006281; GO:0006310; GO:0010212; GO:0016363; GO:0030330; GO:0031398; GO:0035097; GO:0043433; GO:0043542; GO:0044666; GO:0045830; GO:0048304; GO:0051568; GO:0051571; GO:0060261; GO:0060612; GO:0060717; GO:1902749; GO:2001022 20103 XM_044323403.1 0 41 33 34 53 NA NA NA NA NA NA 20104 XR_006396260.1 1 0 7 0 17 NA NA NA NA NA NA 20105 XM_044311764.1 126 167 190 232 178 NA NA NA NA NA NA 20106 XR_003828047.2 29 7 16 32 14 NA NA NA NA NA NA 20107 XR_006392687.1 0 0 93 1 7 NA NA NA NA NA NA 20108 XM_044322964.1 1000 1046 876 803 478 Q7ZWS1 0 tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like (EC 1.3.1.89) (mRNA-dihydrouridine synthase DUS3L) (EC 1.3.1.-) (tRNA-dihydrouridine synthase 3-like) Xenopus laevis (African clawed frog) mRNA processing [GO:0006397]; regulation of translation [GO:0006417]; tRNA dihydrouridine synthesis [GO:0002943] GO:0002943; GO:0006397; GO:0006417; GO:0017150; GO:0046872; GO:0050660 20109 XM_044315195.1 17 12 31 16 29 NA NA NA NA NA NA 20110 XR_006392514.1 11 0 0 0 11 NA NA NA NA NA NA 20111 XM_044306798.1 500 350 266 505 667 Q9DBT9 0 Dimethylglycine dehydrogenase, mitochondrial (EC 1.5.8.4) (ME2GLYDH) Mus musculus (Mouse) amino-acid betaine catabolic process [GO:0006579]; choline catabolic process [GO:0042426]; tetrahydrofolate interconversion [GO:0035999] GO:0005542; GO:0005737; GO:0005739; GO:0005759; GO:0006579; GO:0016491; GO:0035999; GO:0042426; GO:0047865; GO:0050660 20112 XM_029327808.2 81 117 106 72 70 Q96DM1 3.92e-49 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 20113 XM_044316055.1 31 12 38 64 135 NA NA NA NA NA NA 20114 XR_006396560.1 512 0 118 1 0 NA NA NA NA NA NA 20115 XM_029325071.2 1482 1127 760 1573 1212 Q9CWF6 0 Bardet-Biedl syndrome 2 protein homolog Mus musculus (Mouse) adult behavior [GO:0030534]; artery smooth muscle contraction [GO:0014824]; brain morphogenesis [GO:0048854]; cartilage development [GO:0051216]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; fat cell differentiation [GO:0045444]; gene expression [GO:0010467]; Golgi to plasma membrane protein transport [GO:0043001]; hippocampus development [GO:0021766]; leptin-mediated signaling pathway [GO:0033210]; negative regulation of appetite by leptin-mediated signaling pathway [GO:0038108]; negative regulation of gene expression [GO:0010629]; negative regulation of multicellular organism growth [GO:0040015]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of multicellular organism growth [GO:0040018]; protein localization [GO:0008104]; protein localization to organelle [GO:0033365]; regulation of cilium beat frequency involved in ciliary motility [GO:0060296]; response to leptin [GO:0044321]; sperm axoneme assembly [GO:0007288]; striatum development [GO:0021756]; vasodilation [GO:0042311]; visual perception [GO:0007601] GO:0005737; GO:0005902; GO:0007288; GO:0007601; GO:0008104; GO:0010467; GO:0010629; GO:0014824; GO:0016020; GO:0021756; GO:0021766; GO:0021987; GO:0030534; GO:0031514; GO:0032420; GO:0033210; GO:0033365; GO:0034464; GO:0036064; GO:0038108; GO:0040015; GO:0040018; GO:0042311; GO:0043001; GO:0043005; GO:0044321; GO:0045444; GO:0045494; GO:0048854; GO:0051216; GO:0060170; GO:0060271; GO:0060296; GO:0061629; GO:1905515 20116 XM_044319054.1 72 63 0 55 137 Q9VCA2 1.35e-64 Organic cation transporter protein Drosophila melanogaster (Fruit fly) apoptotic process [GO:0006915]; ion transport [GO:0006811] GO:0006811; GO:0006915; GO:0016020; GO:0022857 20117 XM_029353778.2 422 195 110 213 317 P48630 7.16e-117 Omega-6 fatty acid desaturase, endoplasmic reticulum isozyme 1 (EC 1.14.19.-) Glycine max (Soybean) (Glycine hispida) unsaturated fatty acid biosynthetic process [GO:0006636] GO:0005789; GO:0006636; GO:0016491 20118 XR_006395947.1 318 0 229 41 148 NA NA NA NA NA NA 20119 XM_029338639.2 437 221 158 255 164 Q99571 4.16e-116 P2X purinoceptor 4 (P2X4) (ATP receptor) (Purinergic receptor) Homo sapiens (Human) apoptotic signaling pathway [GO:0097190]; behavioral response to pain [GO:0048266]; calcium ion transmembrane transport [GO:0070588]; calcium-mediated signaling [GO:0019722]; cellular response to ATP [GO:0071318]; cellular response to zinc ion [GO:0071294]; endothelial cell activation [GO:0042118]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; neuronal action potential [GO:0019228]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of microglial cell migration [GO:1904141]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein kinase B signaling [GO:0051897]; purinergic nucleotide receptor signaling pathway [GO:0035590]; regulation of blood pressure [GO:0008217]; regulation of cardiac muscle contraction [GO:0055117]; regulation of chemotaxis [GO:0050920]; regulation of sodium ion transport [GO:0002028]; relaxation of cardiac muscle [GO:0055119]; response to ATP [GO:0033198]; response to axon injury [GO:0048678]; response to fluid shear stress [GO:0034405]; response to ischemia [GO:0002931]; sensory perception of pain [GO:0019233]; sensory perception of touch [GO:0050975]; signal transduction [GO:0007165]; tissue homeostasis [GO:0001894] GO:0001614; GO:0001894; GO:0002028; GO:0002931; GO:0004931; GO:0005102; GO:0005507; GO:0005524; GO:0005637; GO:0005765; GO:0005886; GO:0007165; GO:0008217; GO:0008270; GO:0010524; GO:0010614; GO:0014069; GO:0016020; GO:0019228; GO:0019233; GO:0019722; GO:0030054; GO:0032308; GO:0033198; GO:0034220; GO:0034405; GO:0035590; GO:0042118; GO:0042802; GO:0043025; GO:0043195; GO:0043197; GO:0043536; GO:0044297; GO:0045296; GO:0045429; GO:0048266; GO:0048471; GO:0048678; GO:0050850; GO:0050920; GO:0050975; GO:0051897; GO:0051899; GO:0051928; GO:0055117; GO:0055119; GO:0070062; GO:0070588; GO:0071294; GO:0071318; GO:0097190; GO:0099604; GO:1904141; GO:2001028 20120 XM_029347425.2 149 127 87 368 214 O60290 7.93e-77 Zinc finger protein 862 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006355; GO:0046872; GO:0046983 20121 XM_044312438.1 0 10 34 3 4 NA NA NA NA NA NA 20122 XM_044324270.1 2 18 0 1 66 NA NA NA NA NA NA 20123 XR_006396899.1 7 0 7 8 0 NA NA NA NA NA NA 20124 XM_029344493.2 920 588 346 1298 733 NA NA NA NA NA NA 20125 XM_044314653.1 0 15 0 0 0 Q99315 3.81e-77 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 20126 XM_029331140.2 184 68 96 84 156 Q9BUZ4 6.46e-58 TNF receptor-associated factor 4 (EC 2.3.2.27) (Cysteine-rich domain associated with RING and Traf domains protein 1) (Metastatic lymph node gene 62 protein) (MLN 62) (RING finger protein 83) Homo sapiens (Human) activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; innate immune response [GO:0045087]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein kinase activity [GO:0045860]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; respiratory gaseous exchange by respiratory system [GO:0007585]; respiratory tube development [GO:0030323] GO:0001650; GO:0005164; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0005923; GO:0006915; GO:0007250; GO:0007585; GO:0008270; GO:0016740; GO:0019901; GO:0030323; GO:0031625; GO:0031996; GO:0042802; GO:0042981; GO:0043122; GO:0043161; GO:0045087; GO:0045860; GO:0046330; GO:0048471; GO:0050699 20127 XM_044323851.1 129 40 83 33 316 NA NA NA NA NA NA 20128 XM_029341156.2 4304 3050 1599 5351 4150 NA NA NA NA NA NA 20129 XM_044313192.1 16 17 6 0 4 NA NA NA NA NA NA 20130 XM_029345817.2 6874 5398 3673 4582 3247 NA NA NA NA NA NA 20131 XM_044310299.1 52 17 28 44 87 NA NA NA NA NA NA 20132 XM_029333042.2 396 553 188 150 489 Q8NE22 1.56e-75 SET domain-containing protein 9 (EC 2.1.1.-) Homo sapiens (Human) methylation [GO:0032259]; regulation of signal transduction by p53 class mediator [GO:1901796] GO:0005654; GO:0016278; GO:0032259; GO:1901796 20133 XM_044321230.1 0 6 0 2 10 P48040 2.07e-27 Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor) Ovis aries (Sheep) NA GO:0005886; GO:0008502 20134 XM_029355245.2 244 636 293 763 333 NA NA NA NA NA NA 20135 XM_044313676.1 0 0 0 9 33 NA NA NA NA NA NA 20136 XM_029328778.2 20 13 20 0 51 Q5XXP2 5.73e-29 Melanopsin (Opsin-4) Phodopus sungorus (Striped hairy-footed hamster) (Djungarian hamster) hyaloid vascular plexus regression [GO:1990384]; optokinetic behavior [GO:0007634]; phototransduction [GO:0007602]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511]; visual perception [GO:0007601] GO:0005502; GO:0005886; GO:0007601; GO:0007602; GO:0007634; GO:0008020; GO:0016020; GO:0030424; GO:0030425; GO:0042752; GO:0043204; GO:0048511; GO:1990384 20137 XM_029344000.2 0 96 326 92 336 Q6E2N3 2e-58 E3 ubiquitin-protein ligase TRIM33 (EC 2.3.2.27) (Ectodermin homolog) (Protein moonshine) (RING-type E3 ubiquitin transferase TRIM33) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33) Danio rerio (Zebrafish) (Brachydanio rerio) developmental pigmentation [GO:0048066]; embryonic hemopoiesis [GO:0035162]; erythrocyte differentiation [GO:0030218]; fin development [GO:0033333]; macrophage chemotaxis [GO:0048246]; macrophage migration [GO:1905517]; neutrophil chemotaxis [GO:0030593]; neutrophil migration [GO:1990266]; post-embryonic hemopoiesis [GO:0035166]; primitive hemopoiesis [GO:0060215]; protein ubiquitination [GO:0016567]; regulation of transcription elongation by RNA polymerase II [GO:0034243] GO:0003677; GO:0005634; GO:0008270; GO:0016567; GO:0016740; GO:0030218; GO:0030593; GO:0033333; GO:0034243; GO:0035162; GO:0035166; GO:0048066; GO:0048246; GO:0060215; GO:1905517; GO:1990266 20138 XM_029344000.2 0 96 326 92 336 Q6E2N3 5.05e-42 E3 ubiquitin-protein ligase TRIM33 (EC 2.3.2.27) (Ectodermin homolog) (Protein moonshine) (RING-type E3 ubiquitin transferase TRIM33) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33) Danio rerio (Zebrafish) (Brachydanio rerio) developmental pigmentation [GO:0048066]; embryonic hemopoiesis [GO:0035162]; erythrocyte differentiation [GO:0030218]; fin development [GO:0033333]; macrophage chemotaxis [GO:0048246]; macrophage migration [GO:1905517]; neutrophil chemotaxis [GO:0030593]; neutrophil migration [GO:1990266]; post-embryonic hemopoiesis [GO:0035166]; primitive hemopoiesis [GO:0060215]; protein ubiquitination [GO:0016567]; regulation of transcription elongation by RNA polymerase II [GO:0034243] GO:0003677; GO:0005634; GO:0008270; GO:0016567; GO:0016740; GO:0030218; GO:0030593; GO:0033333; GO:0034243; GO:0035162; GO:0035166; GO:0048066; GO:0048246; GO:0060215; GO:1905517; GO:1990266 20139 XR_006395342.1 7 3 0 0 8 NA NA NA NA NA NA 20140 XM_029340984.2 33 72 30 36 52 Q9WUU9 4.69e-50 Germinal-center associated nuclear protein (GANP) (EC 2.3.1.48) (GC-associated DNA primase) Mus musculus (Mouse) mRNA export from nucleus [GO:0006406]; nucleosome organization [GO:0034728]; poly(A)+ mRNA export from nucleus [GO:0016973]; protein transport [GO:0015031]; somatic hypermutation of immunoglobulin genes [GO:0016446] GO:0003676; GO:0003682; GO:0004402; GO:0005634; GO:0005654; GO:0005694; GO:0005737; GO:0005829; GO:0006406; GO:0010484; GO:0015031; GO:0016446; GO:0016973; GO:0031965; GO:0034728; GO:0042393; GO:0044615; GO:0070390 20141 XM_044308058.1 1893 1409 362 2072 1480 P25439 0 ATP-dependent helicase brm (EC 3.6.4.12) (Homeotic gene regulator) (Protein brahma) Drosophila melanogaster (Fruit fly) axonogenesis [GO:0007409]; cell dedifferentiation [GO:0043697]; chromatin remodeling [GO:0006338]; dendrite guidance [GO:0070983]; dendrite morphogenesis [GO:0048813]; hemocyte proliferation [GO:0035172]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of neuroblast proliferation [GO:0007406]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of innate immune response [GO:0045088]; regulation of neuroblast proliferation [GO:1902692]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription initiation-coupled chromatin remodeling [GO:0045815]; ventral cord development [GO:0007419] GO:0001223; GO:0003677; GO:0004386; GO:0005524; GO:0005634; GO:0005700; GO:0006338; GO:0006357; GO:0007406; GO:0007409; GO:0007419; GO:0007474; GO:0008094; GO:0008586; GO:0008587; GO:0016887; GO:0035060; GO:0035172; GO:0036335; GO:0042393; GO:0043697; GO:0045088; GO:0045815; GO:0045893; GO:0045944; GO:0048813; GO:0070983; GO:0140297; GO:0140566; GO:0140658; GO:1902692; GO:2000134; GO:2000648 20142 XM_044319418.1 4 26 15 13 33 NA NA NA NA NA NA 20143 XR_006395740.1 0 53 0 0 33 NA NA NA NA NA NA 20144 XM_044320233.1 0 23 25 0 71 NA NA NA NA NA NA 20145 XM_044313334.1 678 24 124 1249 514 NA NA NA NA NA NA 20146 XM_044317667.1 7 0 0 0 0 Q5SPC5 0 Otoferlin (Fer-1-like protein 2) Danio rerio (Zebrafish) (Brachydanio rerio) neuromuscular process controlling balance [GO:0050885]; plasma membrane organization [GO:0007009]; response to auditory stimulus [GO:0010996]; sensory perception of sound [GO:0007605]; startle response [GO:0001964]; synaptic vesicle exocytosis [GO:0016079]; synaptic vesicle priming [GO:0016082] GO:0000139; GO:0001964; GO:0005509; GO:0005789; GO:0007009; GO:0007605; GO:0010996; GO:0016079; GO:0016082; GO:0016323; GO:0030672; GO:0035612; GO:0042995; GO:0048787; GO:0050885 20147 XM_044317667.1 7 0 0 0 0 Q5SPC5 2.44e-106 Otoferlin (Fer-1-like protein 2) Danio rerio (Zebrafish) (Brachydanio rerio) neuromuscular process controlling balance [GO:0050885]; plasma membrane organization [GO:0007009]; response to auditory stimulus [GO:0010996]; sensory perception of sound [GO:0007605]; startle response [GO:0001964]; synaptic vesicle exocytosis [GO:0016079]; synaptic vesicle priming [GO:0016082] GO:0000139; GO:0001964; GO:0005509; GO:0005789; GO:0007009; GO:0007605; GO:0010996; GO:0016079; GO:0016082; GO:0016323; GO:0030672; GO:0035612; GO:0042995; GO:0048787; GO:0050885 20148 XM_044317667.1 7 0 0 0 0 Q5SPC5 2.44e-106 Otoferlin (Fer-1-like protein 2) Danio rerio (Zebrafish) (Brachydanio rerio) neuromuscular process controlling balance [GO:0050885]; plasma membrane organization [GO:0007009]; response to auditory stimulus [GO:0010996]; sensory perception of sound [GO:0007605]; startle response [GO:0001964]; synaptic vesicle exocytosis [GO:0016079]; synaptic vesicle priming [GO:0016082] GO:0000139; GO:0001964; GO:0005509; GO:0005789; GO:0007009; GO:0007605; GO:0010996; GO:0016079; GO:0016082; GO:0016323; GO:0030672; GO:0035612; GO:0042995; GO:0048787; GO:0050885 20149 XM_044314638.1 81 33 82 35 56 NA NA NA NA NA NA 20150 XM_044328624.1 780 619 644 612 794 NA NA NA NA NA NA 20151 XM_044308399.1 665 2447 1677 470 309 Q2TBA3 1.54e-71 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog (EC 3.4.22.-) (Paracaspase) Mus musculus (Mouse) activation of NF-kappaB-inducing kinase activity [GO:0007250]; B cell activation [GO:0042113]; B-1 B cell differentiation [GO:0001923]; cellular response to lipopolysaccharide [GO:0071222]; innate immune response [GO:0045087]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; nuclear export [GO:0051168]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T-helper 17 cell differentiation [GO:2000321]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of apoptotic process [GO:0042981]; regulation of T cell receptor signaling pathway [GO:0050856]; response to fungus [GO:0009620]; T cell proliferation [GO:0042098]; T cell receptor signaling pathway [GO:0050852] GO:0001650; GO:0001923; GO:0002020; GO:0002096; GO:0002726; GO:0004175; GO:0004197; GO:0004842; GO:0005634; GO:0005737; GO:0005829; GO:0006508; GO:0007250; GO:0008233; GO:0009620; GO:0019209; GO:0031663; GO:0032449; GO:0032731; GO:0032743; GO:0032991; GO:0036094; GO:0042098; GO:0042113; GO:0042802; GO:0042981; GO:0043280; GO:0043621; GO:0045087; GO:0048471; GO:0050852; GO:0050856; GO:0050870; GO:0051092; GO:0051168; GO:0051603; GO:0071222; GO:2000321 20152 XM_029334453.2 1357 609 211 445 656 Q9GLM4 2.03e-110 Tensin-1 (EC 3.1.3.-) Bos taurus (Bovine) fibroblast migration [GO:0010761] GO:0003779; GO:0004721; GO:0005737; GO:0005856; GO:0005925; GO:0009986; GO:0010761; GO:0046872 20153 XM_029334453.2 1357 609 211 445 656 Q9GLM4 7.89e-67 Tensin-1 (EC 3.1.3.-) Bos taurus (Bovine) fibroblast migration [GO:0010761] GO:0003779; GO:0004721; GO:0005737; GO:0005856; GO:0005925; GO:0009986; GO:0010761; GO:0046872 20154 XM_029335501.2 698 339 245 609 1086 Q9FIV6 8.72e-145 Protease Do-like 10, mitochondrial (EC 3.4.21.-) Arabidopsis thaliana (Mouse-ear cress) proteolysis [GO:0006508] GO:0004252; GO:0005759; GO:0006508 20155 XM_029342398.2 23 7 1 13 6 F6QEU4 2.76e-30 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 20156 XM_044325669.1 2 33 43 24 14 NA NA NA NA NA NA 20157 XM_029355572.2 168 152 70 68 57 NA NA NA NA NA NA 20158 XM_044310990.1 7 5 12 0 7 NA NA NA NA NA NA 20159 XM_029324461.2 164 287 162 304 287 NA NA NA NA NA NA 20160 XM_044307155.1 98 0 184 134 173 Q9UNS1 0 Protein timeless homolog (hTIM) Homo sapiens (Human) branching morphogenesis of an epithelial tube [GO:0048754]; cell cycle phase transition [GO:0044770]; cell division [GO:0051301]; cellular response to bleomycin [GO:1904976]; cellular response to cisplatin [GO:0072719]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hydroxyurea [GO:0072711]; circadian rhythm [GO:0007623]; detection of abiotic stimulus [GO:0009582]; DNA repair [GO:0006281]; DNA replication checkpoint signaling [GO:0000076]; lung development [GO:0030324]; morphogenesis of an epithelium [GO:0002009]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; regulation of circadian rhythm [GO:0042752]; replication fork arrest [GO:0043111]; replication fork protection [GO:0048478] GO:0000076; GO:0000785; GO:0002009; GO:0003677; GO:0005634; GO:0005654; GO:0006281; GO:0006974; GO:0007623; GO:0009582; GO:0030324; GO:0031298; GO:0035861; GO:0042752; GO:0042802; GO:0043111; GO:0044770; GO:0045892; GO:0048478; GO:0048754; GO:0051301; GO:0072711; GO:0072719; GO:1904976; GO:1905168; GO:2000781 20161 XM_029337024.2 170 516 402 448 532 NA NA NA NA NA NA 20162 XR_006395209.1 175 1 31 18 71 NA NA NA NA NA NA 20163 XM_044313603.1 149 58 107 150 42 Q7ZXY0 0 Inositol-3-phosphate synthase 1-A (IPS 1-A) (EC 5.5.1.4) (Myo-inositol 1-phosphate synthase A) (MI-1-P synthase A) (MIP synthase A) Xenopus laevis (African clawed frog) inositol biosynthetic process [GO:0006021]; phospholipid biosynthetic process [GO:0008654] GO:0004512; GO:0005737; GO:0006021; GO:0008654 20164 XM_044320626.1 213 33 68 281 78 Q20191 1.57e-50 Zinc metalloproteinase nas-13 (EC 3.4.24.-) (Nematode astacin 13) Caenorhabditis elegans proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0006508; GO:0008270 20165 XM_029341879.2 2693 2739 1593 3702 1569 NA NA NA NA NA NA 20166 XR_006396416.1 15 4 31 6 55 NA NA NA NA NA NA 20167 XM_044328842.1 9 0 0 0 6 NA NA NA NA NA NA 20168 XM_029342512.2 23 1105 446 540 146 NA NA NA NA NA NA 20169 XM_029343758.2 4 56 34 171 0 NA NA NA NA NA NA 20170 XM_044316033.1 4 0 42 57 8 NA NA NA NA NA NA 20171 XM_029331964.2 0 0 480 208 159 B3EWZ3 9.13e-105 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 20172 XM_029331964.2 0 0 480 208 159 B3EWZ3 6.33e-99 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 20173 XM_029331964.2 0 0 480 208 159 B3EWZ3 9.56e-97 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 20174 XM_029331964.2 0 0 480 208 159 B3EWZ3 6.28e-92 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 20175 XM_029331964.2 0 0 480 208 159 B3EWZ3 5.38e-88 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 20176 XM_029331964.2 0 0 480 208 159 B3EWZ3 2.93e-84 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 20177 XM_029331964.2 0 0 480 208 159 B3EWZ3 5.78e-71 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 20178 XM_029331964.2 0 0 480 208 159 B3EWZ3 1.72e-24 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 20179 XM_029345120.2 6 23 0 5 21 Q9WTN0 3e-114 Geranylgeranyl pyrophosphate synthase (GGPP synthase) (GGPPSase) (EC 2.5.1.-) ((2E,6E)-farnesyl diphosphate synthase) (Dimethylallyltranstransferase) (EC 2.5.1.1) (Farnesyl diphosphate synthase) (Farnesyltranstransferase) (EC 2.5.1.29) (Geranylgeranyl diphosphate synthase) (Geranyltranstransferase) (EC 2.5.1.10) Mus musculus (Mouse) farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; geranylgeranyl diphosphate biosynthetic process [GO:0033386]; isoprenoid biosynthetic process [GO:0008299]; isoprenoid metabolic process [GO:0006720] GO:0004161; GO:0004311; GO:0004337; GO:0004659; GO:0005654; GO:0005737; GO:0005829; GO:0006720; GO:0008299; GO:0030018; GO:0033384; GO:0033386; GO:0042802; GO:0045337; GO:0046872; GO:0048471 20180 XM_044328408.1 0 43 13 0 14 NA NA NA NA NA NA 20181 XM_029354591.2 226 10 96 11 80 NA NA NA NA NA NA 20182 XM_029338549.2 5 11 32 0 0 NA NA NA NA NA NA 20183 XM_029337780.2 473 444 40 882 353 NA NA NA NA NA NA 20184 XM_044319896.1 298 165 151 433 396 Q9HCD5 1.28e-30 Nuclear receptor coactivator 5 (NCoA-5) (Coactivator independent of AF-2) (CIA) Homo sapiens (Human) glucose homeostasis [GO:0042593]; insulin receptor signaling pathway [GO:0008286]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of signal transduction [GO:0009966] GO:0000122; GO:0003682; GO:0003714; GO:0003723; GO:0005615; GO:0005654; GO:0008286; GO:0009966; GO:0015629; GO:0042593; GO:0046627 20185 XR_006392859.1 35 7 2 40 28 NA NA NA NA NA NA 20186 XR_006397985.1 26 12 34 9 54 NA NA NA NA NA NA 20187 XM_044315190.1 395 291 160 543 216 NA NA NA NA NA NA 20188 XM_044327262.1 9 2 16 19 23 NA NA NA NA NA NA 20189 XM_029345703.2 611 366 154 670 441 D3ZUQ0 1.69e-23 RILP-like protein 1 (GAPDH's competitor of SIAH1 protein enhances life) (GOSPEL) (Rab-interacting lysosomal-like protein 1) Rattus norvegicus (Rat) cilium assembly [GO:0060271]; epithelial cell morphogenesis [GO:0003382]; protein transport from ciliary membrane to plasma membrane [GO:1903445]; regulation of neuron death [GO:1901214] GO:0003382; GO:0005737; GO:0005813; GO:0005814; GO:0005829; GO:0005929; GO:0016020; GO:0036064; GO:0046983; GO:0060271; GO:1901214; GO:1903445 20190 XM_044323905.1 541 233 213 917 844 P07911 5.62e-47 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Homo sapiens (Human) antibacterial innate immune response [GO:0140367]; apoptotic signaling pathway [GO:0097190]; autophagy [GO:0006914]; cellular calcium ion homeostasis [GO:0006874]; cellular chloride ion homeostasis [GO:0030644]; cellular defense response [GO:0006968]; cellular phosphate ion homeostasis [GO:0030643]; cellular response to unfolded protein [GO:0034620]; cellular sodium ion homeostasis [GO:0006883]; chaperone-mediated protein folding [GO:0061077]; citric acid secretion [GO:0046720]; collecting duct development [GO:0072044]; connective tissue replacement [GO:0097709]; creatinine homeostasis [GO:0097273]; defense response to Gram-negative bacterium [GO:0050829]; endoplasmic reticulum organization [GO:0007029]; glomerular filtration [GO:0003094]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; juxtaglomerular apparatus development [GO:0072051]; leukocyte cell-cell adhesion [GO:0007159]; lipid metabolic process [GO:0006629]; metanephric ascending thin limb development [GO:0072218]; metanephric distal convoluted tubule development [GO:0072221]; metanephric thick ascending limb development [GO:0072233]; micturition [GO:0060073]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell population proliferation [GO:0008285]; neutrophil migration [GO:1990266]; organ or tissue specific immune response [GO:0002251]; peptidyl-threonine phosphorylation [GO:0018107]; potassium ion homeostasis [GO:0055075]; protein localization to vacuole [GO:0072665]; protein transport into plasma membrane raft [GO:0044861]; regulation of blood pressure [GO:0008217]; regulation of protein transport [GO:0051223]; regulation of urine volume [GO:0035809]; renal sodium ion absorption [GO:0070294]; renal urate salt excretion [GO:0097744]; renal water homeostasis [GO:0003091]; response to lipopolysaccharide [GO:0032496]; response to water deprivation [GO:0009414]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; ubiquitin-dependent ERAD pathway [GO:0030433]; urate transport [GO:0015747]; urea transmembrane transport [GO:0071918] GO:0000922; GO:0002251; GO:0003091; GO:0003094; GO:0005201; GO:0005509; GO:0005615; GO:0005783; GO:0005796; GO:0005929; GO:0006629; GO:0006874; GO:0006883; GO:0006914; GO:0006954; GO:0006968; GO:0007029; GO:0007157; GO:0007159; GO:0008217; GO:0008285; GO:0008380; GO:0009410; GO:0009414; GO:0009986; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0018107; GO:0019864; GO:0019898; GO:0030433; GO:0030643; GO:0030644; GO:0032496; GO:0033209; GO:0033555; GO:0034620; GO:0035809; GO:0044861; GO:0046720; GO:0050829; GO:0051223; GO:0055075; GO:0060073; GO:0060170; GO:0061077; GO:0070062; GO:0070294; GO:0071918; GO:0072044; GO:0072051; GO:0072218; GO:0072221; GO:0072233; GO:0072665; GO:0097190; GO:0097273; GO:0097709; GO:0097744; GO:0140367; GO:1990266 20191 XM_029348706.2 13 71 35 48 26 NA NA NA NA NA NA 20192 XM_029334365.2 304 209 186 392 59 Q96SK2 3.94e-87 Transmembrane protein 209 Homo sapiens (Human) NA GO:0016020 20193 XM_044315358.1 31 24 49 56 412 NA NA NA NA NA NA 20194 XM_044327265.1 20 16 90 74 166 NA NA NA NA NA NA 20195 XM_029351712.2 592 218 426 847 710 Q5U249 5.27e-160 Protein ELYS (Protein MEL-28) (xELYS) Xenopus laevis (African clawed frog) mRNA transport [GO:0051028]; protein transport [GO:0015031] GO:0003677; GO:0005643; GO:0005654; GO:0005737; GO:0015031; GO:0051028 20196 XM_044326481.1 362 29 156 235 161 P24552 7.83e-23 D-amino-acid oxidase (DAAO) (DAMOX) (DAO) (EC 1.4.3.3) Fusarium vanettenii (Neocosmospora pisi) D-amino acid metabolic process [GO:0046416] GO:0003884; GO:0005777; GO:0046416; GO:0071949 20197 XM_029330736.2 835 632 807 900 1150 Q8QZR1 7.85e-161 Tyrosine aminotransferase (TAT) (EC 2.6.1.5) (L-tyrosine:2-oxoglutarate aminotransferase) Mus musculus (Mouse) 2-oxoglutarate metabolic process [GO:0006103]; amino acid metabolic process [GO:0006520]; biosynthetic process [GO:0009058]; glutamate metabolic process [GO:0006536]; L-phenylalanine catabolic process [GO:0006559]; response to dexamethasone [GO:0071548]; response to glucocorticoid [GO:0051384]; response to mercury ion [GO:0046689]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; tyrosine catabolic process [GO:0006572] GO:0004838; GO:0005739; GO:0006103; GO:0006520; GO:0006536; GO:0006559; GO:0006572; GO:0006979; GO:0009058; GO:0014070; GO:0016597; GO:0030170; GO:0042802; GO:0046689; GO:0051384; GO:0071548 20198 XM_029326356.2 10 20 63 190 372 NA NA NA NA NA NA 20199 XM_044310879.1 72 124 44 106 64 Q99570 0 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 20200 XM_029356798.2 401 242 295 638 489 Q10835 2.01e-34 Collagenase 3 (EC 3.4.24.-) (Matrix metalloproteinase-13) (MMP-13) Xenopus laevis (African clawed frog) bone morphogenesis [GO:0060349]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508] GO:0004222; GO:0005509; GO:0005518; GO:0005576; GO:0006508; GO:0008270; GO:0022617; GO:0030574; GO:0031012; GO:0060349 20201 XM_029337504.2 13 4 0 3 17 P17844 0 Probable ATP-dependent RNA helicase DDX5 (EC 3.6.4.13) (DEAD box protein 5) (RNA helicase p68) Homo sapiens (Human) alternative mRNA splicing, via spliceosome [GO:0000380]; androgen receptor signaling pathway [GO:0030521]; BMP signaling pathway [GO:0030509]; epithelial to mesenchymal transition [GO:0001837]; intracellular estrogen receptor signaling pathway [GO:0030520]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; miRNA transcription [GO:0061614]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transcription [GO:0009299]; myoblast differentiation [GO:0045445]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nuclear-transcribed mRNA catabolic process [GO:0000956]; positive regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043517]; primary miRNA processing [GO:0031053]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of osteoblast differentiation [GO:0045667]; regulation of skeletal muscle cell differentiation [GO:2001014]; regulation of transcription by RNA polymerase II [GO:0006357]; rhythmic process [GO:0048511] GO:0000122; GO:0000380; GO:0000381; GO:0000398; GO:0000956; GO:0001837; GO:0003723; GO:0003724; GO:0003730; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005829; GO:0006357; GO:0009299; GO:0016020; GO:0016607; GO:0016887; GO:0030509; GO:0030520; GO:0030521; GO:0031053; GO:0035500; GO:0036002; GO:0043021; GO:0043517; GO:0045445; GO:0045667; GO:0046332; GO:0048511; GO:0050681; GO:0060765; GO:0061614; GO:0070062; GO:0070412; GO:0070878; GO:0071013; GO:0072332; GO:1990841; GO:1990904; GO:2001014 20202 XR_006396190.1 49 42 30 110 85 NA NA NA NA NA NA 20203 XR_006391900.1 25 35 27 108 40 NA NA NA NA NA NA 20204 XM_029324717.2 25 56 47 25 53 Q99315 1.13e-84 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 20205 XM_044327260.1 40 18 19 42 81 NA NA NA NA NA NA 20206 XM_029333090.2 155 70 141 113 111 NA NA NA NA NA NA 20207 XM_029338635.2 0 0 0 435 268 Q6DCV0 2.78e-153 WD repeat domain phosphoinositide-interacting protein 4 (WIPI-4) (WD repeat-containing protein 45) Xenopus laevis (African clawed frog) autophagosome assembly [GO:0000045]; cellular response to starvation [GO:0009267]; positive regulation of autophagosome assembly [GO:2000786] GO:0000045; GO:0000407; GO:0009267; GO:0032266; GO:1901981; GO:2000786 20208 XM_044321059.1 31 2 9 0 49 NA NA NA NA NA NA 20209 XR_003823110.2 4 0 12 2 8 NA NA NA NA NA NA 20210 XM_044310757.1 16 0 37 0 67 O70244 2.13e-38 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 20211 XM_044310757.1 16 0 37 0 67 O70244 3e-28 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 20212 XM_044310757.1 16 0 37 0 67 O70244 1.67e-26 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 20213 XM_044310757.1 16 0 37 0 67 O70244 4.63e-26 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 20214 XM_044310757.1 16 0 37 0 67 O70244 9.07e-26 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 20215 XM_044310757.1 16 0 37 0 67 O70244 6.92e-25 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 20216 XM_044310757.1 16 0 37 0 67 O70244 1.81e-24 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 20217 XM_044310757.1 16 0 37 0 67 O70244 5.14e-24 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 20218 XM_044310757.1 16 0 37 0 67 O70244 1.54e-22 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 20219 XM_044320652.1 8 0 12 13 37 NA NA NA NA NA NA 20220 XM_029334084.2 0 29 0 0 0 Q09081 6.94e-145 Potassium voltage-gated channel subfamily A member 2 (KC22) (Voltage-gated potassium channel subunit Kv1.2) Oryctolagus cuniculus (Rabbit) neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233] GO:0005249; GO:0005251; GO:0005789; GO:0005886; GO:0008076; GO:0014059; GO:0019228; GO:0019233; GO:0021633; GO:0030027; GO:0030424; GO:0030425; GO:0031258; GO:0032809; GO:0033010; GO:0034765; GO:0042734; GO:0043194; GO:0043204; GO:0043679; GO:0044224; GO:0045188; GO:0051260; GO:0071805 20221 XM_029350680.2 498 283 265 860 1113 Q9I8C7 2.18e-80 Neuronal acetylcholine receptor subunit alpha-10 (Alpha 10 nAChR) (Nicotinic acetylcholine receptor subunit alpha-10) (NACHR alpha-10) Gallus gallus (Chicken) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; response to auditory stimulus [GO:0010996]; signal transduction [GO:0007165] GO:0004888; GO:0005231; GO:0005262; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0010996; GO:0022848; GO:0030594; GO:0034220; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051899; GO:1904315 20222 XM_029347549.2 140 41 92 76 133 Q9I830 4.5e-75 Potassium voltage-gated channel subfamily A member 2 (Shaker-related potassium channel tsha1) (Trout shaker 1) (Voltage-gated potassium channel subunit Kv1.2) Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) neuronal action potential [GO:0019228]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005251; GO:0005886; GO:0008076; GO:0019228; GO:0034765; GO:0044224; GO:0051260; GO:0071805 20223 XM_029336065.2 111 109 0 0 229 Q6DKP5 5.28e-150 WD repeat-containing protein 13 Pan troglodytes (Chimpanzee) NA GO:0005634; GO:1990841 20224 XR_006397701.1 0 30 47 0 6 NA NA NA NA NA NA 20225 XM_044319688.1 0 10 0 45 155 A6QQV6 3.65e-152 Protein arginine N-methyltransferase 7 (EC 2.1.1.321) (Histone-arginine N-methyltransferase PRMT7) ([Myelin basic protein]-arginine N-methyltransferase PRMT7) Bos taurus (Bovine) cell differentiation [GO:0030154]; peptidyl-arginine methylation [GO:0018216]; regulation of gene expression by genomic imprinting [GO:0006349]; spliceosomal snRNP assembly [GO:0000387] GO:0000387; GO:0004984; GO:0005634; GO:0005829; GO:0005886; GO:0006349; GO:0018216; GO:0030154; GO:0035241; GO:0035243; GO:0044020 20226 XM_029336467.2 10981 6659 6152 16105 14616 P24733 0 Myosin heavy chain, striated muscle Argopecten irradians (Bay scallop) (Aequipecten irradians) NA GO:0003774; GO:0005516; GO:0005524; GO:0016459; GO:0030016; GO:0032982; GO:0051015 20227 XM_044322645.1 877 84 933 185 4021 NA NA NA NA NA NA 20228 XM_029349517.2 451 385 308 408 162 NA NA NA NA NA NA 20229 XM_029332750.2 8 1 0 0 24 NA NA NA NA NA NA 20230 XM_029339264.2 95 0 61 25 85 Q9N2B7 4.85e-39 5-hydroxytryptamine receptor 1B (5-HT-1B) (5-HT1B) (Serotonin receptor 1B) Gorilla gorilla gorilla (Western lowland gorilla) adenylate cyclase-inhibiting serotonin receptor signaling pathway [GO:0007198]; behavior [GO:0007610]; bone remodeling [GO:0046849]; cellular response to alkaloid [GO:0071312]; cellular response to xenobiotic stimulus [GO:0071466]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; negative regulation of serotonin secretion [GO:0014063]; regulation of behavior [GO:0050795]; vasoconstriction [GO:0042310] GO:0004993; GO:0005886; GO:0007187; GO:0007198; GO:0007268; GO:0007610; GO:0014063; GO:0030425; GO:0030594; GO:0042310; GO:0045202; GO:0046849; GO:0050795; GO:0051378; GO:0071312; GO:0071466 20231 XM_044324079.1 3 22 3 11 9 Q9IB89 1.63e-80 Zinc finger protein ZIC 5 (XZic5) (XlZic5) (Zinc finger protein of the cerebellum 5) Xenopus laevis (African clawed frog) nervous system development [GO:0007399]; neural crest formation [GO:0014029] GO:0003677; GO:0005634; GO:0007399; GO:0014029; GO:0046872 20232 XM_029332852.2 90 2 86 1 300 P97767 1.06e-153 Eyes absent homolog 1 (EC 3.1.3.16) (EC 3.1.3.48) Mus musculus (Mouse) anatomical structure development [GO:0048856]; animal organ morphogenesis [GO:0009887]; aorta morphogenesis [GO:0035909]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chromatin organization [GO:0006325]; cochlea morphogenesis [GO:0090103]; double-strand break repair [GO:0006302]; embryonic skeletal system morphogenesis [GO:0048704]; epithelial cell proliferation [GO:0050673]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; inner ear morphogenesis [GO:0042472]; mesodermal cell fate specification [GO:0007501]; metanephros development [GO:0001656]; middle ear morphogenesis [GO:0042474]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; neuron fate specification [GO:0048665]; otic vesicle development [GO:0071599]; otic vesicle morphogenesis [GO:0071600]; outer ear morphogenesis [GO:0042473]; outflow tract morphogenesis [GO:0003151]; pattern specification process [GO:0007389]; pharyngeal system development [GO:0060037]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of secondary heart field cardioblast proliferation [GO:0072513]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein dephosphorylation [GO:0006470]; protein sumoylation [GO:0016925]; regulation of neuron differentiation [GO:0045664]; response to ionizing radiation [GO:0010212]; semicircular canal morphogenesis [GO:0048752]; striated muscle tissue development [GO:0014706]; ureteric bud development [GO:0001657] GO:0001656; GO:0001657; GO:0001658; GO:0003151; GO:0003723; GO:0004725; GO:0005634; GO:0005654; GO:0005737; GO:0006302; GO:0006325; GO:0006470; GO:0007389; GO:0007501; GO:0009887; GO:0010212; GO:0014706; GO:0016604; GO:0016925; GO:0017018; GO:0030154; GO:0032991; GO:0032993; GO:0035909; GO:0042472; GO:0042473; GO:0042474; GO:0045165; GO:0045664; GO:0045739; GO:0045893; GO:0045944; GO:0046872; GO:0048665; GO:0048704; GO:0048752; GO:0048856; GO:0050673; GO:0050679; GO:0060037; GO:0071599; GO:0071600; GO:0072513; GO:0090103; GO:0097192; GO:0140793; GO:2001240 20233 XM_029336964.2 4494 1343 1321 3422 1625 NA NA NA NA NA NA 20234 XM_029353652.2 164 124 38 98 20 P25931 1.41e-23 RYamide receptor (Neuropeptide Y-like receptor) (NPY-R) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218] GO:0001653; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0016020 20235 XM_029323572.2 221 50 97 70 182 Q8VDB2 5.13e-137 Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase (EC 2.4.1.260) (Asparagine-linked glycosylation protein 12 homolog) (Dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichyl-alpha-1,6-mannosyltransferase) (Mannosyltransferase ALG12 homolog) Mus musculus (Mouse) dolichol-linked oligosaccharide biosynthetic process [GO:0006488]; protein N-linked glycosylation [GO:0006487] GO:0000009; GO:0000030; GO:0005789; GO:0006487; GO:0006488; GO:0052917 20236 XM_029345799.2 132 14 94 0 281 Q0DXS3 8.24e-134 Probable RNA-dependent RNA polymerase 1 (OsRDR1) (EC 2.7.7.48) Oryza sativa subsp. japonica (Rice) positive regulation of post-transcriptional gene silencing [GO:0060148]; response to salicylic acid [GO:0009751]; response to virus [GO:0009615]; siRNA processing [GO:0030422]; wax biosynthetic process [GO:0010025] GO:0003723; GO:0003968; GO:0009615; GO:0009751; GO:0010025; GO:0030422; GO:0031380; GO:0060148 20237 XM_029330798.2 1318 1188 862 1653 1235 Q61457 1.31e-98 G1/S-specific cyclin-E1 Mus musculus (Mouse) cell division [GO:0051301]; chromosome organization involved in meiotic cell cycle [GO:0070192]; DNA replication initiation [GO:0006270]; G1/S transition of mitotic cell cycle [GO:0000082]; homologous chromosome pairing at meiosis [GO:0007129]; mitotic cell cycle phase transition [GO:0044772]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cell differentiation [GO:0045597]; positive regulation of mesenchymal stem cell proliferation [GO:1902462]; protein phosphorylation [GO:0006468]; regulation of cell cycle [GO:0051726]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of protein localization [GO:0032880]; telomere maintenance [GO:0000723]; Wnt signaling pathway [GO:0016055] GO:0000079; GO:0000082; GO:0000122; GO:0000307; GO:0000723; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0006270; GO:0006468; GO:0007129; GO:0016055; GO:0016301; GO:0016538; GO:0019901; GO:0032880; GO:0044772; GO:0044877; GO:0045597; GO:0051301; GO:0051726; GO:0070192; GO:0097134; GO:1902462 20238 XR_006397968.1 391 1209 44211 1343 1358 NA NA NA NA NA NA 20239 XR_006393489.1 6 5 0 4 0 NA NA NA NA NA NA 20240 XM_044322200.1 35 46 17 19 36 NA NA NA NA NA NA 20241 XM_044329206.1 131 0 0 62 33 NA NA NA NA NA NA 20242 XM_044313131.1 103 59 42 100 131 P82251 1.61e-138 b(0,+)-type amino acid transporter 1 (b(0,+)AT1) (Glycoprotein-associated amino acid transporter b0,+AT1) (Solute carrier family 7 member 9) Homo sapiens (Human) L-cystine transport [GO:0015811]; neutral amino acid transport [GO:0015804]; protein-containing complex assembly [GO:0065003] GO:0005886; GO:0015175; GO:0015179; GO:0015184; GO:0015804; GO:0015811; GO:0016324; GO:0031526; GO:0042605; GO:0065003 20243 XM_029355580.2 2325 1725 615 1450 825 Q5ZIJ9 2.71e-51 E3 ubiquitin-protein ligase MIB2 (EC 2.3.2.27) (Mind bomb homolog 2) (RING-type E3 ubiquitin transferase MIB2) Gallus gallus (Chicken) Notch signaling pathway [GO:0007219]; protein ubiquitination [GO:0016567] GO:0004842; GO:0005737; GO:0007219; GO:0008270; GO:0016567 20244 XM_029337243.2 74 40 14 69 80 Q3USL1 6.41e-33 Kelch domain-containing protein 9 Mus musculus (Mouse) NA GO:0030332 20245 XM_044323134.1 25 27 23 13 13 NA NA NA NA NA NA 20246 XM_044307390.1 628 943 384 603 612 Q70CQ2 3.04e-27 Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.4.19.12) (Deubiquitinating enzyme 34) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) Homo sapiens (Human) positive regulation of canonical Wnt signaling pathway [GO:0090263]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt signaling pathway [GO:0016055] GO:0004197; GO:0004843; GO:0005634; GO:0005829; GO:0006511; GO:0016055; GO:0016579; GO:0071108; GO:0090263 20247 XR_006392148.1 0 0 1 17 3 NA NA NA NA NA NA 20248 XM_044310647.1 41 16 21 2 44 NA NA NA NA NA NA 20249 XM_029330203.2 2810 2061 1475 2818 2860 Q9UGM3 5.81e-80 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 20250 XM_029330203.2 2810 2061 1475 2818 2860 Q9UGM3 4.79e-59 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 20251 XM_029330203.2 2810 2061 1475 2818 2860 Q9UGM3 1.61e-58 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 20252 XM_029330203.2 2810 2061 1475 2818 2860 Q9UGM3 4.26e-55 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 20253 XM_029330203.2 2810 2061 1475 2818 2860 Q9UGM3 1.75e-44 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 20254 XM_029330203.2 2810 2061 1475 2818 2860 Q9UGM3 4.4e-43 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 20255 XM_029330203.2 2810 2061 1475 2818 2860 Q9UGM3 1.93e-41 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 20256 XM_029330203.2 2810 2061 1475 2818 2860 Q9UGM3 7.4e-41 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 20257 XM_029330203.2 2810 2061 1475 2818 2860 Q9UGM3 1.36e-35 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 20258 XM_029330203.2 2810 2061 1475 2818 2860 Q9UGM3 4.76e-21 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 20259 XM_029356437.2 0 0 64 0 0 NA NA NA NA NA NA 20260 XM_029330445.2 190 389 197 389 0 NA NA NA NA NA NA 20261 XR_006397045.1 4 0 1 0 7 NA NA NA NA NA NA 20262 XM_044313985.1 0 20 0 0 2 NA NA NA NA NA NA 20263 XM_044322478.1 71 1302 852 1356 1725 NA NA NA NA NA NA 20264 XM_029341235.2 0 0 29 0 0 P21758 1.21e-21 Macrophage scavenger receptor types I and II (Macrophage acetylated LDL receptor I and II) (CD antigen CD204) Bos taurus (Bovine) amyloid-beta clearance [GO:0097242]; cholesterol transport [GO:0030301]; establishment of localization in cell [GO:0051649]; lipoprotein transport [GO:0042953]; negative regulation of gene expression [GO:0010629]; phagocytosis, engulfment [GO:0006911]; plasma lipoprotein particle clearance [GO:0034381]; positive regulation of cholesterol storage [GO:0010886]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; protein homotrimerization [GO:0070207]; receptor-mediated endocytosis [GO:0006898]; zymogen activation [GO:0031638] GO:0001540; GO:0004252; GO:0005044; GO:0005581; GO:0005886; GO:0006898; GO:0006911; GO:0010629; GO:0010744; GO:0010886; GO:0019899; GO:0030169; GO:0030301; GO:0030544; GO:0031638; GO:0034362; GO:0034381; GO:0042802; GO:0042953; GO:0051649; GO:0051879; GO:0070207; GO:0097242; GO:0140313 20265 XM_044309927.1 94 30 12 58 46 NA NA NA NA NA NA 20266 XM_044314198.1 0 0 7 0 0 NA NA NA NA NA NA 20267 XM_029351091.2 0 0 0 0 36 P30975 6.47e-24 Tachykinin-like peptides receptor 99D (Tachykinin-like receptor at 99D) (dTKR) Drosophila melanogaster (Fruit fly) detection of chemical stimulus involved in sensory perception of smell [GO:0050911]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; neuropeptide signaling pathway [GO:0007218]; olfactory behavior [GO:0042048]; positive regulation of sensory perception of pain [GO:1904058]; tachykinin receptor signaling pathway [GO:0007217] GO:0004995; GO:0005886; GO:0007186; GO:0007217; GO:0007218; GO:0008188; GO:0016020; GO:0042048; GO:0050805; GO:0050911; GO:1904058 20268 XM_044317501.1 5 28 22 17 31 NA NA NA NA NA NA 20269 XM_029334807.2 1667 747 939 1539 1113 NA NA NA NA NA NA 20270 XM_029356392.2 463 291 472 773 373 Q6ZR37 3.59e-84 Pleckstrin homology domain-containing family G member 7 (PH domain-containing family G member 7) Homo sapiens (Human) Rho protein signal transduction [GO:0007266] GO:0005085; GO:0007266 20271 XM_029336075.2 1114 739 590 826 604 NA NA NA NA NA NA 20272 XM_044326034.1 850 537 568 1533 933 Q9NSN8 5.84e-79 Gamma-1-syntrophin (G1SYN) (Syntrophin-4) (SYN4) Homo sapiens (Human) cell communication [GO:0007154] GO:0003779; GO:0005198; GO:0005634; GO:0005737; GO:0005856; GO:0007154; GO:0008022; GO:0016010; GO:0016013; GO:0032587 20273 XM_044313316.1 195 276 288 601 273 Q47898 5.6e-55 N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase (EC 3.5.1.26) (Aspartylglucosaminidase) (AGA) (Glycosylasparaginase) (N4-(N-acetyl-beta-glucosaminyl)-L-asparagine amidase) [Cleaved into: Glycosylasparaginase alpha chain; Glycosylasparaginase beta chain] Elizabethkingia miricola (Chryseobacterium miricola) proteolysis [GO:0006508] GO:0003948; GO:0006508; GO:0008233; GO:0042597 20274 XM_029347304.2 10 1 34 4 91 O02751 1.39e-27 Craniofacial development protein 2 (p97 bucentaur protein) Bos taurus (Bovine) chromatin remodeling [GO:0006338] GO:0003824; GO:0005634; GO:0005737; GO:0006338 20275 XM_044315790.1 72 34 18 75 8 NA NA NA NA NA NA 20276 XM_029332349.2 517 212 272 409 359 NA NA NA NA NA NA 20277 XM_044323812.1 0 0 27 0 3 NA NA NA NA NA NA 20278 XM_044326958.1 274 247 260 367 450 NA NA NA NA NA NA 20279 XR_006398031.1 67 20 26 65 138 NA NA NA NA NA NA 20280 XR_003825664.2 12 0 0 7 4 NA NA NA NA NA NA 20281 XR_006396305.1 126 153 61 143 178 NA NA NA NA NA NA 20282 XR_006391475.1 412 86 55 68 40 NA NA NA NA NA NA 20283 XM_044319061.1 1012 606 598 1183 1196 A0JP86 3.13e-130 Laminin subunit gamma-1 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell adhesion [GO:0007155] GO:0005576; GO:0005604; GO:0007155 20284 XM_044319061.1 1012 606 598 1183 1196 A0JP86 2.51e-42 Laminin subunit gamma-1 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell adhesion [GO:0007155] GO:0005576; GO:0005604; GO:0007155 20285 XM_044319061.1 1012 606 598 1183 1196 A0JP86 1.47e-26 Laminin subunit gamma-1 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell adhesion [GO:0007155] GO:0005576; GO:0005604; GO:0007155 20286 XM_044319061.1 1012 606 598 1183 1196 A0JP86 6.88e-24 Laminin subunit gamma-1 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell adhesion [GO:0007155] GO:0005576; GO:0005604; GO:0007155 20287 XM_044319061.1 1012 606 598 1183 1196 A0JP86 7.42e-24 Laminin subunit gamma-1 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell adhesion [GO:0007155] GO:0005576; GO:0005604; GO:0007155 20288 XM_044310877.1 6 3 9 32 7 NA NA NA NA NA NA 20289 XR_006397399.1 17 8 4 6 13 NA NA NA NA NA NA 20290 XM_044326352.1 18 2 9 0 5 P58307 3.16e-25 Orexin/Hypocretin receptor type 1 (Hypocretin receptor type 1) (Orexin receptor type 1) (Ox-1-R) (Ox1-R) (Ox1R) Mus musculus (Mouse) feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0004930; GO:0005886; GO:0007186; GO:0007218; GO:0007631; GO:0016499; GO:0017046; GO:0051480; GO:0070374 20291 XR_006393703.1 92 0 0 10 21 NA NA NA NA NA NA 20292 XM_044321363.1 27 0 44 0 2 NA NA NA NA NA NA 20293 XM_044326024.1 0 0 29 19 126 Q9UKV8 6.97e-130 Protein argonaute-2 (Argonaute2) (hAgo2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (PAZ Piwi domain protein) (PPD) (Protein slicer) Homo sapiens (Human) miRNA metabolic process [GO:0010586]; miRNA processing [GO:0035196]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; miRNA-mediated gene silencing by mRNA destabilization [GO:0035279]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; negative regulation of translational initiation [GO:0045947]; positive regulation of angiogenesis [GO:0045766]; positive regulation of gene expression [GO:0010628]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of trophoblast cell migration [GO:1901165]; post-embryonic development [GO:0009791]; pre-miRNA processing [GO:0031054]; RISC complex assembly [GO:0070922]; RNA secondary structure unwinding [GO:0010501]; RNA-mediated gene silencing [GO:0031047]; RNA-mediated post-transcriptional gene silencing [GO:0035194]; siRNA processing [GO:0030422]; siRNA-mediated gene silencing by mRNA destabilization [GO:0090625]; translation [GO:0006412] GO:0000340; GO:0000932; GO:0000993; GO:0001046; GO:0003723; GO:0003725; GO:0003727; GO:0003743; GO:0004521; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005844; GO:0005845; GO:0006412; GO:0008022; GO:0009791; GO:0010501; GO:0010586; GO:0010628; GO:0016020; GO:0016442; GO:0030422; GO:0030425; GO:0031047; GO:0031054; GO:0035194; GO:0035196; GO:0035197; GO:0035198; GO:0035278; GO:0035279; GO:0036464; GO:0042985; GO:0045766; GO:0045944; GO:0045947; GO:0046872; GO:0060213; GO:0070062; GO:0070551; GO:0070578; GO:0070922; GO:0090624; GO:0090625; GO:0098808; GO:1900153; GO:1901165; GO:1990904 20294 XM_044321572.1 496 132 184 610 181 NA NA NA NA NA NA 20295 XM_029346911.2 123 71 45 70 267 O00716 3.55e-71 Transcription factor E2F3 (E2F-3) Homo sapiens (Human) G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of fat cell proliferation [GO:0070345]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; protein import into nucleus [GO:0006606]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription initiation at RNA polymerase II promoter [GO:0006367] GO:0000082; GO:0000785; GO:0000978; GO:0000981; GO:0000987; GO:0001216; GO:0001228; GO:0003700; GO:0005634; GO:0005654; GO:0006357; GO:0006367; GO:0006606; GO:0008284; GO:0043565; GO:0045944; GO:0046983; GO:0070345; GO:0090575; GO:1905461; GO:1990837 20296 XM_029340433.2 336 32 89 74 35 Q96QE2 7.26e-174 Proton myo-inositol cotransporter (H(+)-myo-inositol cotransporter) (Hmit) (H(+)-myo-inositol symporter) (Solute carrier family 2 member 13) Homo sapiens (Human) myo-inositol transport [GO:0015798]; positive regulation of amyloid-beta formation [GO:1902004]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104] GO:0002020; GO:0005365; GO:0005366; GO:0005737; GO:0005886; GO:0015798; GO:0016020; GO:0016324; GO:0022857; GO:0030426; GO:0031090; GO:0042995; GO:0043231; GO:0044297; GO:0051117; GO:0055085; GO:0071944; GO:0097450; GO:0150104; GO:1902004 20297 XR_003828294.2 2 6 2 4 8 NA NA NA NA NA NA 20298 XM_029346357.2 0 27 22 89 47 NA NA NA NA NA NA 20299 XM_029327186.2 124 165 129 163 82 NA NA NA NA NA NA 20300 XR_006396161.1 990 402 504 891 919 Q86SG6 2.8e-127 Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never in mitosis A-related kinase 8) (NimA-related protein kinase 8) (Nima-related protein kinase 12a) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; chromosome segregation [GO:0007059]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; protein phosphorylation [GO:0006468]; regulation of hippo signaling [GO:0035330] GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005929; GO:0006468; GO:0007059; GO:0007368; GO:0007507; GO:0009887; GO:0035330; GO:0046872; GO:0097543; GO:0097546; GO:0106310 20301 XR_006396161.1 990 402 504 891 919 Q86SG6 6.48e-76 Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never in mitosis A-related kinase 8) (NimA-related protein kinase 8) (Nima-related protein kinase 12a) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; chromosome segregation [GO:0007059]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; protein phosphorylation [GO:0006468]; regulation of hippo signaling [GO:0035330] GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005929; GO:0006468; GO:0007059; GO:0007368; GO:0007507; GO:0009887; GO:0035330; GO:0046872; GO:0097543; GO:0097546; GO:0106310 20302 XM_044319034.1 16 0 0 1179 356 Q01460 1.24e-102 Di-N-acetylchitobiase (EC 3.2.1.-) Rattus norvegicus (Rat) chitin catabolic process [GO:0006032]; oligosaccharide catabolic process [GO:0009313] GO:0004568; GO:0005764; GO:0006032; GO:0008061; GO:0009313; GO:0016798 20303 XM_044327988.1 307 173 151 393 416 Q149F3 0 Eukaryotic peptide chain release factor GTP-binding subunit ERF3B (Eukaryotic peptide chain release factor subunit 3b) (eRF3b) (G1 to S phase transition protein 2 homolog) Mus musculus (Mouse) cell cycle [GO:0007049]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; translation [GO:0006412] GO:0000184; GO:0003747; GO:0003924; GO:0005525; GO:0006412; GO:0007049; GO:0018444 20304 XM_029327707.2 1129 803 2307 670 719 Q96DM1 2.48e-47 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 20305 XM_044321974.1 368 298 148 615 130 NA NA NA NA NA NA 20306 XR_006392331.1 68 26 6 74 222 NA NA NA NA NA NA 20307 XR_006397244.1 45 31 0 0 6 NA NA NA NA NA NA 20308 XM_029344903.2 10 0 0 194 35 Q5FVH4 4.95e-23 AKT-interacting protein (Fused toes protein homolog) Rattus norvegicus (Rat) apoptotic process [GO:0006915]; early endosome to late endosome transport [GO:0045022]; endosome organization [GO:0007032]; endosome to lysosome transport [GO:0008333]; lysosome organization [GO:0007040]; positive regulation of protein binding [GO:0032092]; positive regulation of protein phosphorylation [GO:0001934]; protein localization to perinuclear region of cytoplasm [GO:1905719]; protein polyubiquitination [GO:0000209]; protein transport [GO:0015031] GO:0000209; GO:0001934; GO:0005634; GO:0005829; GO:0005886; GO:0006915; GO:0007032; GO:0007040; GO:0008333; GO:0015031; GO:0032092; GO:0045022; GO:0061631; GO:0070695; GO:1905719 20309 XR_006391396.1 104 58 34 76 124 NA NA NA NA NA NA 20310 XM_044324988.1 20 5 12 13 79 NA NA NA NA NA NA 20311 XM_029348274.2 144 69 59 187 170 Q9VKA4 2.87e-100 Probable G-protein coupled receptor CG31760 Drosophila melanogaster (Fruit fly) NA GO:0004930; GO:0005886 20312 XM_029353768.2 691 658 480 497 389 Q64729 1.2e-87 TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (ESK2) (Transforming growth factor-beta receptor type I) (TGF-beta receptor type I) (TbetaR-I) Mus musculus (Mouse) activin receptor signaling pathway [GO:0032924]; angiogenesis [GO:0001525]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; anterior/posterior pattern specification [GO:0009952]; apoptotic process [GO:0006915]; artery morphogenesis [GO:0048844]; blastocyst development [GO:0001824]; cardiac epithelial to mesenchymal transition [GO:0060317]; cell motility [GO:0048870]; cellular response to growth factor stimulus [GO:0071363]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen fibril organization [GO:0030199]; coronary artery morphogenesis [GO:0060982]; embryonic cranial skeleton morphogenesis [GO:0048701]; endothelial cell activation [GO:0042118]; endothelial cell migration [GO:0043542]; endothelial cell proliferation [GO:0001935]; epicardium morphogenesis [GO:1905223]; epithelial to mesenchymal transition [GO:0001837]; filopodium assembly [GO:0046847]; germ cell migration [GO:0008354]; heart development [GO:0007507]; in utero embryonic development [GO:0001701]; intracellular signal transduction [GO:0035556]; kidney development [GO:0001822]; lens development in camera-type eye [GO:0002088]; male gonad development [GO:0008584]; mesenchymal cell differentiation [GO:0048762]; negative regulation of apoptotic process [GO:0043066]; negative regulation of chondrocyte differentiation [GO:0032331]; negative regulation of endothelial cell differentiation [GO:0045602]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of miRNA transcription [GO:1902894]; nervous system development [GO:0007399]; neuron fate commitment [GO:0048663]; parathyroid gland development [GO:0060017]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; pharyngeal system development [GO:0060037]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation [GO:1905007]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of tight junction disassembly [GO:1905075]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gene expression [GO:0010468]; regulation of protein binding [GO:0043393]; regulation of protein ubiquitination [GO:0031396]; response to cholesterol [GO:0070723]; response to estrogen [GO:0043627]; roof of mouth development [GO:0060021]; signal transduction [GO:0007165]; skeletal system development [GO:0001501]; skeletal system morphogenesis [GO:0048705]; thymus development [GO:0048538]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ventricular compact myocardium morphogenesis [GO:0003223]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222] GO:0001501; GO:0001525; GO:0001701; GO:0001822; GO:0001824; GO:0001837; GO:0001935; GO:0001937; GO:0001938; GO:0002088; GO:0003222; GO:0003223; GO:0004672; GO:0004674; GO:0005024; GO:0005025; GO:0005102; GO:0005114; GO:0005524; GO:0005634; GO:0005768; GO:0005886; GO:0005901; GO:0005923; GO:0006355; GO:0006468; GO:0006915; GO:0007165; GO:0007179; GO:0007399; GO:0007507; GO:0008284; GO:0008354; GO:0008584; GO:0009791; GO:0009952; GO:0009986; GO:0010468; GO:0010628; GO:0010717; GO:0010718; GO:0010862; GO:0016020; GO:0016323; GO:0016324; GO:0016361; GO:0018105; GO:0018107; GO:0019838; GO:0030199; GO:0030307; GO:0030335; GO:0031396; GO:0031625; GO:0032331; GO:0032924; GO:0032991; GO:0035556; GO:0042118; GO:0043065; GO:0043066; GO:0043235; GO:0043393; GO:0043410; GO:0043542; GO:0043627; GO:0044877; GO:0045121; GO:0045602; GO:0045893; GO:0046332; GO:0046777; GO:0046847; GO:0046872; GO:0048179; GO:0048185; GO:0048538; GO:0048663; GO:0048701; GO:0048705; GO:0048762; GO:0048844; GO:0048870; GO:0050431; GO:0051491; GO:0051496; GO:0051897; GO:0060017; GO:0060021; GO:0060037; GO:0060043; GO:0060317; GO:0060389; GO:0060391; GO:0060412; GO:0060978; GO:0060982; GO:0070021; GO:0070411; GO:0070723; GO:0071363; GO:0071560; GO:1902894; GO:1902895; GO:1905007; GO:1905075; GO:1905223; GO:2001235; GO:2001237 20313 XM_029324490.2 611 448 527 1302 455 NA NA NA NA NA NA 20314 XR_006397444.1 0 0 0 0 8 NA NA NA NA NA NA 20315 XR_006392674.1 33 10 5 9 24 NA NA NA NA NA NA 20316 XM_029341321.2 40 53 53 22 121 NA NA NA NA NA NA 20317 XM_044316410.1 1125 1509 732 1676 1549 Q6PD21 2e-44 SH2 domain-containing adapter protein B Mus musculus (Mouse) angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; B cell proliferation [GO:0042100]; blood vessel development [GO:0001568]; blood vessel morphogenesis [GO:0048514]; hematopoietic stem cell proliferation [GO:0071425]; hemopoiesis [GO:0030097]; negative regulation of oocyte maturation [GO:1900194]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of T-helper cell differentiation [GO:0045624]; T cell receptor signaling pathway [GO:0050852] GO:0001525; GO:0001568; GO:0001784; GO:0005654; GO:0005829; GO:0005886; GO:0006469; GO:0006915; GO:0030097; GO:0030159; GO:0036464; GO:0042100; GO:0045624; GO:0045931; GO:0048514; GO:0050852; GO:0071425; GO:1900194 20318 XM_029335585.2 10373 10054 6787 12614 14381 P40939 0 Trifunctional enzyme subunit alpha, mitochondrial (78 kDa gastrin-binding protein) (Monolysocardiolipin acyltransferase) (EC 2.3.1.-) (TP-alpha) [Includes: Long-chain enoyl-CoA hydratase (EC 4.2.1.17); Long chain 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.211)] Homo sapiens (Human) cardiolipin acyl-chain remodeling [GO:0035965]; fatty acid beta-oxidation [GO:0006635]; response to insulin [GO:0032868]; response to xenobiotic stimulus [GO:0009410] GO:0000062; GO:0003857; GO:0003985; GO:0004300; GO:0005739; GO:0005743; GO:0006635; GO:0009410; GO:0016507; GO:0016508; GO:0016509; GO:0032868; GO:0035965; GO:0042645; GO:0044877; GO:0070403 20319 XM_044320188.1 62 103 49 76 53 NA NA NA NA NA NA 20320 XM_044325979.1 0 0 77 0 0 Q0IHA2 1.83e-51 Elongator complex protein 6 (Protein TMEM103) Xenopus laevis (African clawed frog) positive regulation of cell migration [GO:0030335]; tRNA wobble uridine modification [GO:0002098] GO:0002098; GO:0030335; GO:0033588 20321 XM_029340142.2 7940 7824 6171 20061 19334 P38529 3.2e-62 Heat shock factor protein 1 (HSF 1) (HSF 3A) (HSTF 3A) (Heat shock transcription factor 1) (HSTF 1) Gallus gallus (Chicken) cellular response to cadmium ion [GO:0071276]; cellular response to gamma radiation [GO:0071480]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; MAPK cascade [GO:0000165]; mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; negative regulation of double-strand break repair via nonhomologous end joining [GO:2001033]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cell cycle G1/S phase transition [GO:1902808]; positive regulation of cell cycle G2/M phase transition [GO:1902751]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of mRNA polyadenylation [GO:1900365]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein homotrimerization [GO:0070207]; regulation of transcription by RNA polymerase II [GO:0006357]; response to heat [GO:0009408]; response to light stimulus [GO:0009416] GO:0000122; GO:0000165; GO:0000776; GO:0000785; GO:0000978; GO:0001046; GO:0001228; GO:0003677; GO:0003700; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0006281; GO:0006357; GO:0006397; GO:0008284; GO:0009408; GO:0009416; GO:0010628; GO:0016605; GO:0031072; GO:0031333; GO:0031490; GO:0034605; GO:0042803; GO:0043565; GO:0043621; GO:0045931; GO:0045944; GO:0048471; GO:0051028; GO:0070207; GO:0071276; GO:0071480; GO:0097165; GO:0097431; GO:0101031; GO:1900365; GO:1902751; GO:1902808; GO:2001033 20322 XM_044311443.1 0 0 0 0 7 NA NA NA NA NA NA 20323 XM_044313040.1 15 7 11 6 59 Q96AY4 2.19e-94 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20324 XM_044313040.1 15 7 11 6 59 Q96AY4 1.79e-92 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20325 XM_044313040.1 15 7 11 6 59 Q96AY4 3.33e-91 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20326 XM_044313040.1 15 7 11 6 59 Q96AY4 5.03e-87 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20327 XM_044313040.1 15 7 11 6 59 Q96AY4 1.11e-64 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20328 XM_044313040.1 15 7 11 6 59 Q96AY4 1.03e-48 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20329 XM_044313040.1 15 7 11 6 59 Q96AY4 6.36e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20330 XM_029344830.2 51 84 21 56 26 Q9C9U5 8.87e-26 Probable serine/threonine-protein kinase SIS8 (EC 2.7.11.1) (MAPKK kinase SIS8) (Protein SUGAR INSENSITIVE 8) Arabidopsis thaliana (Mouse-ear cress) protein phosphorylation [GO:0006468]; response to salt stress [GO:0009651]; sugar mediated signaling pathway [GO:0010182] GO:0004674; GO:0004712; GO:0005524; GO:0005634; GO:0005739; GO:0006468; GO:0009651; GO:0010182; GO:0106310 20331 XM_044325073.1 47 65 61 34 102 NA NA NA NA NA NA 20332 XM_044317700.1 100 1 67 37 112 Q9HC77 7.37e-88 Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1) Homo sapiens (Human) astral microtubule nucleation [GO:0030954]; cell division [GO:0051301]; centriole elongation [GO:0061511]; centriole replication [GO:0007099]; cilium assembly [GO:0060271]; microtubule nucleation [GO:0007020]; microtubule polymerization [GO:0046785]; motile cilium assembly [GO:0044458]; non-motile cilium assembly [GO:1905515]; positive regulation of centriole elongation [GO:1903724]; positive regulation of centriole replication [GO:0046601]; positive regulation of establishment of protein localization [GO:1904951]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of non-motile cilium assembly [GO:1902857]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of spindle assembly [GO:1905832]; regulation of centriole replication [GO:0046599]; regulation of mitotic spindle organization [GO:0060236]; smoothened signaling pathway [GO:0007224] GO:0003713; GO:0005634; GO:0005737; GO:0005813; GO:0005814; GO:0005829; GO:0005874; GO:0007020; GO:0007099; GO:0007224; GO:0008275; GO:0015631; GO:0019901; GO:0019904; GO:0030954; GO:0036064; GO:0042802; GO:0043015; GO:0044458; GO:0046427; GO:0046599; GO:0046601; GO:0046785; GO:0051301; GO:0060236; GO:0060271; GO:0061511; GO:0120099; GO:1900087; GO:1902857; GO:1903724; GO:1904951; GO:1905515; GO:1905832 20333 XM_044317700.1 100 1 67 37 112 Q9HC77 6.25e-34 Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1) Homo sapiens (Human) astral microtubule nucleation [GO:0030954]; cell division [GO:0051301]; centriole elongation [GO:0061511]; centriole replication [GO:0007099]; cilium assembly [GO:0060271]; microtubule nucleation [GO:0007020]; microtubule polymerization [GO:0046785]; motile cilium assembly [GO:0044458]; non-motile cilium assembly [GO:1905515]; positive regulation of centriole elongation [GO:1903724]; positive regulation of centriole replication [GO:0046601]; positive regulation of establishment of protein localization [GO:1904951]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of non-motile cilium assembly [GO:1902857]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of spindle assembly [GO:1905832]; regulation of centriole replication [GO:0046599]; regulation of mitotic spindle organization [GO:0060236]; smoothened signaling pathway [GO:0007224] GO:0003713; GO:0005634; GO:0005737; GO:0005813; GO:0005814; GO:0005829; GO:0005874; GO:0007020; GO:0007099; GO:0007224; GO:0008275; GO:0015631; GO:0019901; GO:0019904; GO:0030954; GO:0036064; GO:0042802; GO:0043015; GO:0044458; GO:0046427; GO:0046599; GO:0046601; GO:0046785; GO:0051301; GO:0060236; GO:0060271; GO:0061511; GO:0120099; GO:1900087; GO:1902857; GO:1903724; GO:1904951; GO:1905515; GO:1905832 20334 XM_029357195.2 246 341 134 269 358 NA NA NA NA NA NA 20335 XM_044328787.1 0 5 9 7 29 NA NA NA NA NA NA 20336 XM_029353445.2 23 0 6 0 42 P47747 7.41e-31 Histamine H2 receptor (H2R) (HH2R) (Gastric receptor I) Cavia porcellus (Guinea pig) gastric acid secretion [GO:0001696]; positive regulation of vasoconstriction [GO:0045907] GO:0001696; GO:0004969; GO:0005886; GO:0045907 20337 XM_029335407.2 97 244 113 114 189 NA NA NA NA NA NA 20338 XM_029355850.2 849 557 437 460 712 A3KP59 1.61e-171 Ribosomal oxygenase 1 (Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66) (EC 1.14.11.-, EC 1.14.11.27) (Histone lysine demethylase NO66) Danio rerio (Zebrafish) (Brachydanio rerio) chromatin organization [GO:0006325]; histone H3-K36 demethylation [GO:0070544]; histone H3-K4 demethylation [GO:0034720]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of osteoblast differentiation [GO:0045668] GO:0005506; GO:0005634; GO:0005654; GO:0005730; GO:0006325; GO:0016706; GO:0032453; GO:0034647; GO:0034720; GO:0036139; GO:0045668; GO:0045892; GO:0051864; GO:0070544; GO:0140457; GO:0140680 20339 XM_044329128.1 103 39 69 0 43 Q8BJQ2 6.87e-46 Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.4.19.12) (Deubiquitinating enzyme 1) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) [Cleaved into: Ubiquitin carboxyl-terminal hydrolase 1, N-terminal fragment] Mus musculus (Mouse) DNA repair [GO:0006281]; monoubiquitinated protein deubiquitination [GO:0035520]; protein deubiquitination [GO:0016579]; regulation of DNA repair [GO:0006282]; response to UV [GO:0009411]; skeletal system development [GO:0001501]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0001501; GO:0004197; GO:0004843; GO:0005634; GO:0005654; GO:0005829; GO:0006281; GO:0006282; GO:0006511; GO:0008233; GO:0009411; GO:0016579; GO:0035520 20340 XM_044309455.1 403 198 40 79 23 NA NA NA NA NA NA 20341 XM_029346551.2 1864 1451 564 1052 1173 P41384 3.38e-25 Cyclin-dependent kinases regulatory subunit (SUC1 homolog) Patella vulgata (Common limpet) cell cycle [GO:0007049]; cell division [GO:0051301] GO:0007049; GO:0016538; GO:0051301 20342 XM_044310481.1 107 321 141 16 209 NA NA NA NA NA NA 20343 XM_044324038.1 86385 109449 81848 83900 49233 P42577 1.64e-64 Soma ferritin (EC 1.16.3.1) Lymnaea stagnalis (Great pond snail) (Helix stagnalis) cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826] GO:0004322; GO:0005737; GO:0006826; GO:0006879; GO:0008199 20344 XM_044324038.1 86385 109449 81848 83900 49233 P42577 8.34e-41 Soma ferritin (EC 1.16.3.1) Lymnaea stagnalis (Great pond snail) (Helix stagnalis) cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826] GO:0004322; GO:0005737; GO:0006826; GO:0006879; GO:0008199 20345 XM_029340251.2 845 502 254 891 1026 A2VDU3 7.7e-126 Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) Bos taurus (Bovine) apoptotic process [GO:0006915]; I-kappaB phosphorylation [GO:0007252]; JNK cascade [GO:0007254]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of JUN kinase activity [GO:0043507] GO:0000287; GO:0004709; GO:0005524; GO:0005737; GO:0005886; GO:0006915; GO:0007252; GO:0007254; GO:0043123; GO:0043507; GO:0106310 20346 XM_029342342.2 305 169 104 220 307 B0BM20 4.74e-46 Enolase 4 (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) glycolytic process [GO:0006096] GO:0000015; GO:0000287; GO:0004634; GO:0006096 20347 XM_044323646.1 257 0 28 464 88 Q16975 1.15e-34 Calcium-independent protein kinase C (EC 2.7.11.13) (APL II) Aplysia californica (California sea hare) protein phosphorylation [GO:0006468] GO:0004698; GO:0005524; GO:0006468; GO:0016020; GO:0046872; GO:0106310 20348 XM_029348165.2 1338 962 467 894 849 Q8NBP0 0 Tetratricopeptide repeat protein 13 (TPR repeat protein 13) Homo sapiens (Human) NA NA 20349 XM_029344871.2 19 10 11 5 29 P53454 9.44e-21 D(5)-like dopamine receptor Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) regulation of biological quality [GO:0065008] GO:0004930; GO:0005886; GO:0065008 20350 XM_044318256.1 464 366 379 542 468 E9Q634 0 Unconventional myosin-Ie (Unconventional myosin 1E) Mus musculus (Mouse) actin filament organization [GO:0007015]; endocytosis [GO:0006897]; glomerular basement membrane development [GO:0032836]; glomerular filtration [GO:0003094]; hemopoiesis [GO:0030097]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; nitrogen compound metabolic process [GO:0006807]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; podocyte development [GO:0072015]; post-embryonic hemopoiesis [GO:0035166]; vasculogenesis [GO:0001570]; vesicle transport along actin filament [GO:0030050] GO:0000146; GO:0001570; GO:0001701; GO:0001822; GO:0003094; GO:0005516; GO:0005524; GO:0005737; GO:0005856; GO:0005886; GO:0005902; GO:0005903; GO:0005912; GO:0006807; GO:0006897; GO:0007015; GO:0015629; GO:0016459; GO:0016887; GO:0030050; GO:0030097; GO:0031982; GO:0032437; GO:0032836; GO:0032991; GO:0035091; GO:0035166; GO:0044877; GO:0045334; GO:0048008; GO:0051015; GO:0072015 20351 XR_006392183.1 23 1 13 0 7 NA NA NA NA NA NA 20352 XM_044309610.1 14 4 99 2 22 NA NA NA NA NA NA 20353 XM_044322489.1 180 0 0 0 0 NA NA NA NA NA NA 20354 XM_029350634.2 4276 3749 3557 4316 4152 Q9BUJ2 3.91e-127 Heterogeneous nuclear ribonucleoprotein U-like protein 1 (Adenovirus early region 1B-associated protein 5) (E1B-55 kDa-associated protein 5) (E1B-AP5) Homo sapiens (Human) response to virus [GO:0009615]; RNA processing [GO:0006396] GO:0003723; GO:0005634; GO:0005654; GO:0006396; GO:0009615; GO:0019899; GO:0045202; GO:1990904 20355 XM_044319189.1 76 22 6 92 25 NA NA NA NA NA NA 20356 XR_003827343.2 30 63 17 64 20 NA NA NA NA NA NA 20357 XM_029351622.2 9 4 14 0 67 NA NA NA NA NA NA 20358 XR_006394295.1 78 47 58 150 307 NA NA NA NA NA NA 20359 XM_044328782.1 81 7 84 1 359 NA NA NA NA NA NA 20360 XM_029348303.2 2321 4394 3284 2265 3079 Q6DGJ3 1.07e-33 Mitochondrial import inner membrane translocase subunit Tim13 Danio rerio (Zebrafish) (Brachydanio rerio) protein insertion into mitochondrial inner membrane [GO:0045039] GO:0005743; GO:0042719; GO:0045039; GO:0046872 20361 XM_044316918.1 784 894 608 775 523 Q8WY64 1.76e-72 E3 ubiquitin-protein ligase MYLIP (EC 2.3.2.27) (Inducible degrader of the LDL-receptor) (Idol) (Myosin regulatory light chain interacting protein) (MIR) (RING-type E3 ubiquitin transferase MYLIP) Homo sapiens (Human) cholesterol homeostasis [GO:0042632]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of neuron projection development [GO:0010977]; nervous system development [GO:0007399]; positive regulation of protein catabolic process [GO:0045732]; protein destabilization [GO:0031648]; protein ubiquitination [GO:0016567]; regulation of low-density lipoprotein particle receptor catabolic process [GO:0032803]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004842; GO:0005829; GO:0005856; GO:0005886; GO:0006511; GO:0007399; GO:0008092; GO:0010977; GO:0010989; GO:0016567; GO:0031648; GO:0032803; GO:0042632; GO:0045732; GO:0046872; GO:0061630 20362 XM_029339950.2 604 221 301 371 630 Q5RID7 1.22e-128 Sorting nexin-17 Danio rerio (Zebrafish) (Brachydanio rerio) intracellular protein transport [GO:0006886]; signal transduction [GO:0007165]; vesicle-mediated transport [GO:0016192] GO:0005769; GO:0005829; GO:0006886; GO:0007165; GO:0016192; GO:0030659; GO:0031410; GO:0035091 20363 XM_044306970.1 13 8 0 10 37 NA NA NA NA NA NA 20364 XM_044313077.1 24 31 5 11 41 NA NA NA NA NA NA 20365 XM_044310070.1 33 8 0 64 26 NA NA NA NA NA NA 20366 XM_044325851.1 12 223 21 171 283 Q8N2S1 8.23e-60 Latent-transforming growth factor beta-binding protein 4 (LTBP-4) Homo sapiens (Human) elastic fiber assembly [GO:0048251]; hormone secretion [GO:0046879]; protein folding [GO:0006457]; regulation of cell growth [GO:0001558]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001527; GO:0001558; GO:0005024; GO:0005178; GO:0005509; GO:0005539; GO:0005576; GO:0005615; GO:0006457; GO:0007179; GO:0017015; GO:0031012; GO:0046879; GO:0048251; GO:0050431; GO:0062023 20367 XM_044325851.1 12 223 21 171 283 Q8N2S1 1.45e-40 Latent-transforming growth factor beta-binding protein 4 (LTBP-4) Homo sapiens (Human) elastic fiber assembly [GO:0048251]; hormone secretion [GO:0046879]; protein folding [GO:0006457]; regulation of cell growth [GO:0001558]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001527; GO:0001558; GO:0005024; GO:0005178; GO:0005509; GO:0005539; GO:0005576; GO:0005615; GO:0006457; GO:0007179; GO:0017015; GO:0031012; GO:0046879; GO:0048251; GO:0050431; GO:0062023 20368 XM_044309197.1 575 79 239 611 147 NA NA NA NA NA NA 20369 XM_044327119.1 847 1012 627 1075 844 Q9NXB0 2.64e-140 Tectonic-like complex member MKS1 (Meckel syndrome type 1 protein) Homo sapiens (Human) branching morphogenesis of an epithelial tube [GO:0048754]; cardiac septum morphogenesis [GO:0060411]; cilium assembly [GO:0060271]; common bile duct development [GO:0061009]; determination of left/right symmetry [GO:0007368]; embryonic brain development [GO:1990403]; embryonic digit morphogenesis [GO:0042733]; embryonic skeletal system development [GO:0048706]; epithelial structure maintenance [GO:0010669]; head development [GO:0060322]; inner ear receptor cell stereocilium organization [GO:0060122]; motile cilium assembly [GO:0044458]; neural tube closure [GO:0001843]; non-motile cilium assembly [GO:1905515]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:1901620]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation [GO:0003271] GO:0001843; GO:0003271; GO:0005737; GO:0005813; GO:0005814; GO:0005829; GO:0007368; GO:0010669; GO:0016020; GO:0036038; GO:0036064; GO:0042733; GO:0044458; GO:0048706; GO:0048754; GO:0060122; GO:0060271; GO:0060322; GO:0060411; GO:0060828; GO:0061009; GO:1901620; GO:1905515; GO:1990403; GO:2000095 20370 XM_029344200.2 29 27 4 100 42 Q4HX89 1.87e-25 Protein BTN1 Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1) (Wheat head blight fungus) (Fusarium graminearum) amino acid transport [GO:0006865] GO:0005774; GO:0006865 20371 XR_006397417.1 52 19 498 0 463 NA NA NA NA NA NA 20372 XM_029339393.2 542 387 259 418 362 Q9SVG0 1.11e-62 Amino acid transporter AVT3C (AtAvt3C) (Aromatic and neutral amino acid transporter-like protein 2) Arabidopsis thaliana (Mouse-ear cress) amino acid transmembrane transport [GO:0003333]; neutral amino acid transport [GO:0015804] GO:0003333; GO:0005774; GO:0015175; GO:0015179; GO:0015804 20373 XM_044321947.1 924 651 1662 615 1437 NA NA NA NA NA NA 20374 XM_044325460.1 977 1068 770 1237 1213 Q9QYC7 0 Vitamin K-dependent gamma-carboxylase (EC 4.1.1.90) (Gamma-glutamyl carboxylase) (Peptidyl-glutamate 4-carboxylase) (Vitamin K gamma glutamyl carboxylase) Mus musculus (Mouse) peptidyl-glutamic acid carboxylation [GO:0017187] GO:0005789; GO:0008488; GO:0017187; GO:0019842; GO:0043231 20375 XM_044326752.1 677 241 104 81 97 NA NA NA NA NA NA 20376 XM_029340147.2 29 38 162 15 136 O46504 3.91e-169 Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial (PDPr) Bos taurus (Bovine) NA GO:0005759; GO:0016491 20377 XM_029358255.2 0 0 0 0 76 NA NA NA NA NA NA 20378 XM_029351323.2 343 1061 209 210 203 NA NA NA NA NA NA 20379 XM_029348138.2 9 34 0 71 14 P49338 2.55e-122 Protein Wnt-4 (XWnt-4) Xenopus laevis (African clawed frog) embryonic pattern specification [GO:0009880]; glomus development [GO:0072013]; nephrostome development [GO:0039018]; pronephric nephron tubule development [GO:0039020]; Wnt signaling pathway [GO:0016055] GO:0005102; GO:0005576; GO:0009880; GO:0016055; GO:0039018; GO:0039020; GO:0072013 20380 XM_044310983.1 2613 3607 1744 2819 1556 Q3T108 2.96e-107 Proteasome subunit beta type-4 Bos taurus (Bovine) proteasomal protein catabolic process [GO:0010498] GO:0005634; GO:0005654; GO:0005739; GO:0005839; GO:0010498; GO:0019774; GO:0036064 20381 XM_044311537.1 229 26 125 41 81 Q7RTR2 2.43e-43 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20382 XM_044311537.1 229 26 125 41 81 Q7RTR2 1.19e-35 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20383 XM_044311537.1 229 26 125 41 81 Q7RTR2 8.74e-26 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20384 XM_044307984.1 0 0 9 0 20 NA NA NA NA NA NA 20385 XM_044323360.1 838 967 1511 1987 2679 Q8C6K9 2.48e-76 Collagen alpha-6(VI) chain Mus musculus (Mouse) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 20386 XM_044323360.1 838 967 1511 1987 2679 Q8C6K9 6.28e-64 Collagen alpha-6(VI) chain Mus musculus (Mouse) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 20387 XM_044323360.1 838 967 1511 1987 2679 Q8C6K9 2.16e-57 Collagen alpha-6(VI) chain Mus musculus (Mouse) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 20388 XM_044323360.1 838 967 1511 1987 2679 Q8C6K9 2.47e-57 Collagen alpha-6(VI) chain Mus musculus (Mouse) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 20389 XM_044323360.1 838 967 1511 1987 2679 Q8C6K9 1.25e-47 Collagen alpha-6(VI) chain Mus musculus (Mouse) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 20390 XM_044323360.1 838 967 1511 1987 2679 Q8C6K9 5.33e-38 Collagen alpha-6(VI) chain Mus musculus (Mouse) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 20391 XM_044323360.1 838 967 1511 1987 2679 Q8C6K9 1.12e-36 Collagen alpha-6(VI) chain Mus musculus (Mouse) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 20392 XM_044323360.1 838 967 1511 1987 2679 Q8C6K9 1.31e-35 Collagen alpha-6(VI) chain Mus musculus (Mouse) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 20393 XM_044319505.1 0 0 0 0 8 NA NA NA NA NA NA 20394 XR_006392842.1 8 6 6 20 63 NA NA NA NA NA NA 20395 XM_044327535.1 0 0 47 0 0 P27467 2.74e-109 Protein Wnt-3a Mus musculus (Mouse) animal organ morphogenesis [GO:0009887]; anterior/posterior pattern specification [GO:0009952]; axis elongation involved in somitogenesis [GO:0090245]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; B cell proliferation [GO:0042100]; BMP signaling pathway [GO:0030509]; calcium ion transmembrane transport via low voltage-gated calcium channel [GO:0090676]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment [GO:0061317]; cardiac muscle cell fate commitment [GO:0060923]; cell fate commitment [GO:0045165]; cell population proliferation [GO:0008283]; cell proliferation in forebrain [GO:0021846]; cell proliferation in midbrain [GO:0033278]; cell-cell signaling [GO:0007267]; COP9 signalosome assembly [GO:0010387]; determination of left/right symmetry [GO:0007368]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral neural tube patterning [GO:0021904]; extracellular matrix organization [GO:0030198]; fat cell differentiation [GO:0045444]; heart looping [GO:0001947]; hemopoiesis [GO:0030097]; hippocampus development [GO:0021766]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; mammary gland development [GO:0030879]; mesoderm development [GO:0007498]; midbrain development [GO:0030901]; modulation of chemical synaptic transmission [GO:0050804]; myoblast differentiation [GO:0045445]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of dopaminergic neuron differentiation [GO:1904339]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of heart induction by canonical Wnt signaling pathway [GO:0003136]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron death [GO:1901215]; negative regulation of neuron projection development [GO:0010977]; neurogenesis [GO:0022008]; neuron differentiation [GO:0030182]; osteoblast differentiation [GO:0001649]; paraxial mesodermal cell fate commitment [GO:0048343]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation [GO:2000081]; positive regulation of cardiac muscle cell differentiation [GO:2000727]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell-cell adhesion mediated by cadherin [GO:2000049]; positive regulation of collateral sprouting in absence of injury [GO:0048697]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of dermatome development [GO:0061184]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of hepatocyte proliferation [GO:2000347]; positive regulation of mesodermal cell fate specification [GO:0048337]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein binding [GO:0032092]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor internalization [GO:0002092]; positive regulation of skeletal muscle tissue development [GO:0048643]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; protein localization [GO:0008104]; regulation of axonogenesis [GO:0050770]; regulation of cell differentiation [GO:0045595]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of postsynapse to nucleus signaling pathway [GO:1905539]; regulation of presynapse assembly [GO:1905606]; regulation of RNA biosynthetic process [GO:2001141]; regulation of synapse organization [GO:0050807]; secondary palate development [GO:0062009]; signal transduction [GO:0007165]; skeletal muscle cell differentiation [GO:0035914]; somatic stem cell division [GO:0048103]; somitogenesis [GO:0001756]; spinal cord association neuron differentiation [GO:0021527]; transcription by RNA polymerase II [GO:0006366]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874] GO:0001649; GO:0001701; GO:0001756; GO:0001819; GO:0001934; GO:0001947; GO:0002092; GO:0003136; GO:0003713; GO:0005102; GO:0005109; GO:0005125; GO:0005576; GO:0005615; GO:0005788; GO:0006366; GO:0007165; GO:0007267; GO:0007368; GO:0007409; GO:0007411; GO:0007498; GO:0008104; GO:0008283; GO:0008284; GO:0009887; GO:0009952; GO:0009986; GO:0010387; GO:0010628; GO:0010977; GO:0016055; GO:0019904; GO:0021527; GO:0021766; GO:0021846; GO:0021874; GO:0021904; GO:0022008; GO:0030097; GO:0030168; GO:0030182; GO:0030198; GO:0030509; GO:0030879; GO:0030890; GO:0030901; GO:0032092; GO:0033138; GO:0033278; GO:0035914; GO:0036342; GO:0039706; GO:0042100; GO:0042472; GO:0042802; GO:0043280; GO:0045165; GO:0045202; GO:0045444; GO:0045445; GO:0045595; GO:0045599; GO:0045860; GO:0045893; GO:0045944; GO:0048018; GO:0048103; GO:0048337; GO:0048343; GO:0048643; GO:0048697; GO:0048843; GO:0050768; GO:0050770; GO:0050804; GO:0050807; GO:0051091; GO:0060070; GO:0060923; GO:0061098; GO:0061184; GO:0061317; GO:0062009; GO:0070507; GO:0070527; GO:0071542; GO:0090245; GO:0090263; GO:0090676; GO:0098978; GO:1901215; GO:1903078; GO:1904339; GO:1905539; GO:1905606; GO:1990851; GO:1990909; GO:2000049; GO:2000081; GO:2000179; GO:2000347; GO:2000727; GO:2001141 20396 XM_044326216.1 1 4 7 7 1 Q96AY4 9.29e-88 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20397 XM_044326216.1 1 4 7 7 1 Q96AY4 1.3e-86 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20398 XM_044326216.1 1 4 7 7 1 Q96AY4 7.84e-76 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20399 XM_044326216.1 1 4 7 7 1 Q96AY4 1.57e-73 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20400 XM_044326216.1 1 4 7 7 1 Q96AY4 1.77e-71 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20401 XM_044326216.1 1 4 7 7 1 Q96AY4 2.77e-70 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20402 XM_044326216.1 1 4 7 7 1 Q96AY4 3.39e-70 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20403 XM_044326216.1 1 4 7 7 1 Q96AY4 3.19e-58 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20404 XM_044326216.1 1 4 7 7 1 Q96AY4 8.28e-48 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20405 XM_044326216.1 1 4 7 7 1 Q96AY4 4.76e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20406 XM_044326216.1 1 4 7 7 1 Q96AY4 7.14e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20407 XM_029335344.2 438 245 178 291 0 Q5QNQ6 6.61e-154 Oxysterol-binding protein 2 Mus musculus (Mouse) spermatid development [GO:0007286] GO:0005829; GO:0005886; GO:0007286; GO:0015248; GO:0015485; GO:0016020; GO:0032934; GO:0043231; GO:0097038; GO:0097440 20408 XM_029335344.2 438 245 178 291 0 Q5QNQ6 6.84e-76 Oxysterol-binding protein 2 Mus musculus (Mouse) spermatid development [GO:0007286] GO:0005829; GO:0005886; GO:0007286; GO:0015248; GO:0015485; GO:0016020; GO:0032934; GO:0043231; GO:0097038; GO:0097440 20409 XM_044307081.1 982 628 641 909 821 NA NA NA NA NA NA 20410 XM_029355012.2 27 3 31 67 45 Q3UQ28 3.95e-31 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 20411 XM_029355012.2 27 3 31 67 45 Q3UQ28 6.96e-30 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 20412 XM_044319520.1 640 943 299 122 45 NA NA NA NA NA NA 20413 XR_006395433.1 57 0 8 13 80 NA NA NA NA NA NA 20414 XM_044309934.1 0 0 0 0 7 P34586 6.38e-39 Transient-receptor-potential-like protein (TRP homologous cation channel protein 1) Caenorhabditis elegans calcium ion transmembrane transport [GO:0070588]; regulation of cytosolic calcium ion concentration [GO:0051480]; single fertilization [GO:0007338] GO:0005886; GO:0007338; GO:0015279; GO:0034703; GO:0051480; GO:0070588; GO:0070679 20415 XR_006394986.1 71 0 19 60 16 NA NA NA NA NA NA 20416 XM_044326763.1 13 0 9 17 0 Q09575 3.25e-21 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 20417 XM_029349705.2 6 2 3 1 5 NA NA NA NA NA NA 20418 XM_029347270.2 93 26 74 40 54 NA NA NA NA NA NA 20419 XM_044306789.1 14 18 5 20 1 NA NA NA NA NA NA 20420 XM_044327811.1 0 0 0 6 0 P0CT39 4.85e-80 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 20421 XM_029352303.2 8979 9954 5250 6070 4229 P25787 1.41e-144 Proteasome subunit alpha type-2 (Macropain subunit C3) (Multicatalytic endopeptidase complex subunit C3) (Proteasome component C3) Homo sapiens (Human) proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; response to virus [GO:0009615] GO:0000502; GO:0000932; GO:0005576; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005839; GO:0009615; GO:0010498; GO:0019773; GO:0034774; GO:0043161; GO:0070062; GO:1904813 20422 XM_044312907.1 314 110 123 198 330 F1RWC3 9.99e-69 Cubilin (Intrinsic factor-cobalamin receptor) Sus scrofa (Pig) cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031] GO:0005509; GO:0005765; GO:0005768; GO:0005905; GO:0008203; GO:0015031; GO:0016324; GO:0031419 20423 XM_044312907.1 314 110 123 198 330 F1RWC3 9.44e-60 Cubilin (Intrinsic factor-cobalamin receptor) Sus scrofa (Pig) cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031] GO:0005509; GO:0005765; GO:0005768; GO:0005905; GO:0008203; GO:0015031; GO:0016324; GO:0031419 20424 XM_044312907.1 314 110 123 198 330 F1RWC3 4.31e-48 Cubilin (Intrinsic factor-cobalamin receptor) Sus scrofa (Pig) cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031] GO:0005509; GO:0005765; GO:0005768; GO:0005905; GO:0008203; GO:0015031; GO:0016324; GO:0031419 20425 XM_044312907.1 314 110 123 198 330 F1RWC3 1.05e-42 Cubilin (Intrinsic factor-cobalamin receptor) Sus scrofa (Pig) cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031] GO:0005509; GO:0005765; GO:0005768; GO:0005905; GO:0008203; GO:0015031; GO:0016324; GO:0031419 20426 XM_044312907.1 314 110 123 198 330 F1RWC3 6.52e-31 Cubilin (Intrinsic factor-cobalamin receptor) Sus scrofa (Pig) cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031] GO:0005509; GO:0005765; GO:0005768; GO:0005905; GO:0008203; GO:0015031; GO:0016324; GO:0031419 20427 XM_044312907.1 314 110 123 198 330 F1RWC3 1.47e-29 Cubilin (Intrinsic factor-cobalamin receptor) Sus scrofa (Pig) cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031] GO:0005509; GO:0005765; GO:0005768; GO:0005905; GO:0008203; GO:0015031; GO:0016324; GO:0031419 20428 XM_044312907.1 314 110 123 198 330 F1RWC3 3.27e-23 Cubilin (Intrinsic factor-cobalamin receptor) Sus scrofa (Pig) cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031] GO:0005509; GO:0005765; GO:0005768; GO:0005905; GO:0008203; GO:0015031; GO:0016324; GO:0031419 20429 XM_044312907.1 314 110 123 198 330 F1RWC3 1.73e-21 Cubilin (Intrinsic factor-cobalamin receptor) Sus scrofa (Pig) cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031] GO:0005509; GO:0005765; GO:0005768; GO:0005905; GO:0008203; GO:0015031; GO:0016324; GO:0031419 20430 XM_044310146.1 17 6 8 26 8 NA NA NA NA NA NA 20431 XR_006395898.1 14 135 1 0 26 NA NA NA NA NA NA 20432 XM_044324478.1 20 16 160 1 18 NA NA NA NA NA NA 20433 XM_044309049.1 3526 9817 649 4842 2458 Q9GT45 1.11e-57 40S ribosomal protein S26 Anopheles gambiae (African malaria mosquito) cytoplasmic translation [GO:0002181] GO:0002181; GO:0003729; GO:0003735; GO:0022627; GO:0042788; GO:0098556 20434 XM_029358431.2 0 77 43 0 0 NA NA NA NA NA NA 20435 XM_044313709.1 92 0 0 0 0 Q9W735 1.29e-86 Prominin-1-A (Prominin-like protein 1) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005783; GO:0005793; GO:0005886; GO:0005902; GO:0005929; GO:0009986; GO:0015485; GO:0016324; GO:0031528; GO:0071914 20436 XM_044316355.1 69 28 30 24 10 NA NA NA NA NA NA 20437 XR_006392359.1 0 0 0 10 9 NA NA NA NA NA NA 20438 XR_006393397.1 154 265 118 195 66 NA NA NA NA NA NA 20439 XM_029331262.2 24 106 38 27 9 NA NA NA NA NA NA 20440 XM_029338778.2 3944 2467 1236 2316 1086 P36895 5.65e-163 Bone morphogenetic protein receptor type-1A (BMP type-1A receptor) (BMPR-1A) (EC 2.7.11.30) (Activin receptor-like kinase 3) (ALK-3) (BMP-2/BMP-4 receptor) (Serine/threonine-protein kinase receptor R5) (SKR5) (CD antigen CD292) Mus musculus (Mouse) angiogenesis [GO:0001525]; anterior/posterior pattern specification [GO:0009952]; atrioventricular node cell development [GO:0060928]; atrioventricular valve development [GO:0003171]; BMP signaling pathway [GO:0030509]; BMP signaling pathway involved in heart development [GO:0061312]; cardiac conduction system development [GO:0003161]; cardiac right ventricle morphogenesis [GO:0003215]; cartilage development [GO:0051216]; cellular response to BMP stimulus [GO:0071773]; cellular response to growth factor stimulus [GO:0071363]; central nervous system neuron differentiation [GO:0021953]; chondrocyte differentiation [GO:0002062]; developmental growth [GO:0048589]; dorsal aorta morphogenesis [GO:0035912]; dorsal/ventral axis specification [GO:0009950]; dorsal/ventral pattern formation [GO:0009953]; ectoderm development [GO:0007398]; embryonic digit morphogenesis [GO:0042733]; embryonic morphogenesis [GO:0048598]; embryonic organ development [GO:0048568]; endocardial cushion formation [GO:0003272]; endocardial cushion morphogenesis [GO:0003203]; endoderm development [GO:0007492]; epithelial cell proliferation [GO:0050673]; fibrous ring of heart morphogenesis [GO:1905285]; heart development [GO:0007507]; heart formation [GO:0060914]; heart morphogenesis [GO:0003007]; hindlimb morphogenesis [GO:0035137]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; lateral mesoderm development [GO:0048368]; lung development [GO:0030324]; mesendoderm development [GO:0048382]; mesoderm formation [GO:0001707]; mitral valve morphogenesis [GO:0003183]; Mullerian duct regression [GO:0001880]; negative regulation of gene expression [GO:0010629]; negative regulation of muscle cell differentiation [GO:0051148]; negative regulation of neurogenesis [GO:0050768]; negative regulation of smooth muscle cell migration [GO:0014912]; nervous system development [GO:0007399]; neural crest cell development [GO:0014032]; neural plate mediolateral regionalization [GO:0021998]; neural plate pattern specification [GO:0060896]; odontogenesis of dentin-containing tooth [GO:0042475]; osteoblast differentiation [GO:0001649]; outflow tract morphogenesis [GO:0003151]; outflow tract septum morphogenesis [GO:0003148]; paraxial mesoderm development [GO:0048339]; paraxial mesoderm structural organization [GO:0048352]; pattern specification process [GO:0007389]; pharyngeal arch artery morphogenesis [GO:0061626]; pituitary gland development [GO:0021983]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cardiac ventricle development [GO:1904414]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of gene expression [GO:0010628]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta2 production [GO:0032915]; positive regulation of vascular associated smooth muscle cell proliferation [GO:1904707]; protein phosphorylation [GO:0006468]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of cellular senescence [GO:2000772]; regulation of lateral mesodermal cell fate specification [GO:0048378]; roof of mouth development [GO:0060021]; somatic stem cell population maintenance [GO:0035019]; somitogenesis [GO:0001756]; tricuspid valve morphogenesis [GO:0003186]; ventricular compact myocardium morphogenesis [GO:0003223]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222] GO:0001525; GO:0001649; GO:0001701; GO:0001707; GO:0001756; GO:0001880; GO:0002053; GO:0002062; GO:0003007; GO:0003148; GO:0003151; GO:0003161; GO:0003171; GO:0003183; GO:0003186; GO:0003203; GO:0003215; GO:0003222; GO:0003223; GO:0003272; GO:0004674; GO:0005025; GO:0005524; GO:0005886; GO:0005901; GO:0006468; GO:0006955; GO:0007389; GO:0007398; GO:0007399; GO:0007492; GO:0007507; GO:0009897; GO:0009950; GO:0009952; GO:0009953; GO:0009986; GO:0010628; GO:0010629; GO:0010862; GO:0014032; GO:0014912; GO:0019211; GO:0021953; GO:0021983; GO:0021998; GO:0030324; GO:0030425; GO:0030501; GO:0030509; GO:0032915; GO:0035019; GO:0035137; GO:0035912; GO:0036122; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0043235; GO:0043539; GO:0045669; GO:0045944; GO:0046332; GO:0046872; GO:0048339; GO:0048352; GO:0048368; GO:0048378; GO:0048382; GO:0048568; GO:0048589; GO:0048598; GO:0050673; GO:0050679; GO:0050768; GO:0051148; GO:0051216; GO:0060021; GO:0060043; GO:0060045; GO:0060391; GO:0060412; GO:0060896; GO:0060914; GO:0060928; GO:0061312; GO:0061626; GO:0071363; GO:0071773; GO:0098821; GO:0140537; GO:1902895; GO:1904414; GO:1904707; GO:1905285; GO:2000772 20441 XR_006395085.1 868 973 524 1331 1258 NA NA NA NA NA NA 20442 XM_029337978.2 21 13 112 179 197 P0C6B8 3.99e-54 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 20443 XM_044309944.1 311 12 262 1055 397 P18433 6.9e-133 Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (EC 3.1.3.48) Homo sapiens (Human) insulin receptor signaling pathway [GO:0008286]; integrin-mediated signaling pathway [GO:0007229]; modulation of chemical synaptic transmission [GO:0050804]; protein dephosphorylation [GO:0006470]; protein phosphorylation [GO:0006468]; regulation of focal adhesion assembly [GO:0051893] GO:0004725; GO:0005001; GO:0005886; GO:0005925; GO:0006468; GO:0006470; GO:0007229; GO:0008286; GO:0016020; GO:0043235; GO:0050804; GO:0051893; GO:0070062; GO:0097060; GO:0098685 20444 XM_029328614.2 124 120 22 32 0 P47224 4.81e-28 Guanine nucleotide exchange factor MSS4 (Rab-interacting factor) Homo sapiens (Human) membrane fusion [GO:0061025]; post-Golgi vesicle-mediated transport [GO:0006892]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264] GO:0005085; GO:0005829; GO:0006892; GO:0007264; GO:0008270; GO:0015031; GO:0016020; GO:0061025 20445 XM_044323517.1 4 15 0 15 9 NA NA NA NA NA NA 20446 XM_044326489.1 0 0 0 0 57 A0JPE1 3.09e-28 Divergent protein kinase domain 1B (Protein FAM69B) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005789 20447 XM_029358286.2 32 0 0 26 134 Q6DJ06 2.56e-54 LIM domain transcription factor LMO4.2 (LIM domain only protein 4.2) (LMO-4.2) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell differentiation [GO:0030154]; gastrulation [GO:0007369]; mesoderm development [GO:0007498]; negative regulation of neuron differentiation [GO:0045665]; nervous system development [GO:0007399]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0003712; GO:0007369; GO:0007399; GO:0007498; GO:0030154; GO:0045665; GO:0045944; GO:0046872 20448 XM_029328477.2 249 166 124 207 183 Q9WVK8 1.42e-81 Cholesterol 24-hydroxylase (CH24H) (EC 1.14.14.25) (Cholesterol 24-monooxygenase) (Cholesterol 24S-hydroxylase) (Cytochrome P450 46A1) Mus musculus (Mouse) cholesterol catabolic process [GO:0006707]; progesterone metabolic process [GO:0042448]; protein localization to membrane raft [GO:1903044]; regulation of long-term synaptic potentiation [GO:1900271]; xenobiotic metabolic process [GO:0006805] GO:0005506; GO:0005789; GO:0006707; GO:0006805; GO:0008395; GO:0020037; GO:0030425; GO:0033781; GO:0042448; GO:0062184; GO:0098793; GO:0098794; GO:1900271; GO:1903044 20449 XM_029331541.2 439 119 84 122 24 Q9WVK8 6.75e-94 Cholesterol 24-hydroxylase (CH24H) (EC 1.14.14.25) (Cholesterol 24-monooxygenase) (Cholesterol 24S-hydroxylase) (Cytochrome P450 46A1) Mus musculus (Mouse) cholesterol catabolic process [GO:0006707]; progesterone metabolic process [GO:0042448]; protein localization to membrane raft [GO:1903044]; regulation of long-term synaptic potentiation [GO:1900271]; xenobiotic metabolic process [GO:0006805] GO:0005506; GO:0005789; GO:0006707; GO:0006805; GO:0008395; GO:0020037; GO:0030425; GO:0033781; GO:0042448; GO:0062184; GO:0098793; GO:0098794; GO:1900271; GO:1903044 20450 XM_044309587.1 85 134 79 82 109 O00370 2.3e-49 LINE-1 retrotransposable element ORF2 protein (ORF2p) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)] Homo sapiens (Human) DNA recombination [GO:0006310]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; reverse transcription involved in RNA-mediated transposition [GO:0032199]; transposition, RNA-mediated [GO:0032197] GO:0003723; GO:0003964; GO:0006310; GO:0009036; GO:0032197; GO:0032199; GO:0046872; GO:0090305 20451 XM_044309587.1 85 134 79 82 109 O00370 2.3e-49 LINE-1 retrotransposable element ORF2 protein (ORF2p) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)] Homo sapiens (Human) DNA recombination [GO:0006310]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; reverse transcription involved in RNA-mediated transposition [GO:0032199]; transposition, RNA-mediated [GO:0032197] GO:0003723; GO:0003964; GO:0006310; GO:0009036; GO:0032197; GO:0032199; GO:0046872; GO:0090305 20452 XM_029330467.2 12 6 39 8 56 Q708S6 6.27e-49 Acid-sensing ion channel 1C (ASIC1-C) (Acid-sensing ion channel 1.3-C) (Amiloride-sensitive cation channel 2-C, neuronal-C) (ZASIC1.3) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to pH [GO:0071467]; protein homotrimerization [GO:0070207]; sodium ion transmembrane transport [GO:0035725] GO:0005261; GO:0005886; GO:0015280; GO:0035725; GO:0044736; GO:0070207; GO:0071467 20453 XM_029346964.2 106 103 48 55 103 Q6PC60 1.08e-58 Histone H2B 3 Danio rerio (Zebrafish) (Brachydanio rerio) nucleosome assembly [GO:0006334] GO:0000785; GO:0000786; GO:0003677; GO:0005634; GO:0006334; GO:0030527; GO:0046982 20454 XR_006398012.1 107 6 2 64 67 NA NA NA NA NA NA 20455 XM_029338095.2 2093 1717 943 1351 996 P56597 1.13e-91 Nucleoside diphosphate kinase homolog 5 (NDK-H 5) (NDP kinase homolog 5) (Inhibitor of p53-induced apoptosis-beta) (IPIA-beta) (Testis-specific nm23 homolog) (nm23-H5) Homo sapiens (Human) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; CTP biosynthetic process [GO:0006241]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; GTP biosynthetic process [GO:0006183]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside metabolic process [GO:0009116]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]; UTP biosynthetic process [GO:0006228]; ventricular system development [GO:0021591] GO:0003341; GO:0003351; GO:0004550; GO:0005576; GO:0005929; GO:0006165; GO:0006183; GO:0006228; GO:0006241; GO:0007283; GO:0007286; GO:0009116; GO:0021591; GO:0036126; GO:0051649; GO:0060271; GO:1902176 20456 XM_029342477.2 220 83 48 226 73 NA NA NA NA NA NA 20457 XM_029342073.2 42 12 3 23 10 Q5VXJ0 1.6e-109 Lipase member K (EC 3.1.1.-) (Lipase-like abhydrolase domain-containing protein 2) Homo sapiens (Human) cornification [GO:0070268]; lipid catabolic process [GO:0016042] GO:0004465; GO:0005576; GO:0016042; GO:0043231; GO:0070268 20458 XM_029339900.2 10398 9981 6207 10051 7024 Q15084 1.38e-176 Protein disulfide-isomerase A6 (EC 5.3.4.1) (Endoplasmic reticulum protein 5) (ER protein 5) (ERp5) (Protein disulfide isomerase P5) (Thioredoxin domain-containing protein 7) Homo sapiens (Human) protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976] GO:0003756; GO:0005615; GO:0005783; GO:0005788; GO:0005789; GO:0005793; GO:0005829; GO:0005886; GO:0006457; GO:0015035; GO:0034663; GO:0034976; GO:0042470; GO:0070062 20459 XM_044320163.1 326 24 93 348 288 Q3URF8 7.75e-23 BTB/POZ domain-containing protein KCTD21 (KCASH2 protein) (Potassium channel tetramerization domain-containing protein 21) Mus musculus (Mouse) negative regulation of smoothened signaling pathway [GO:0045879]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0006511; GO:0016567; GO:0042802; GO:0042826; GO:0045879; GO:0051260; GO:0097602 20460 XM_044322069.1 3 27 7 15 11 Q94K49 2.11e-33 Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1 (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) epigenetic regulation of gene expression [GO:0040029] GO:0003682; GO:0004518; GO:0005634; GO:0035098; GO:0035102; GO:0040029; GO:0046872 20461 XM_044315486.1 42 28 36 9 86 Q9M2U3 1.86e-30 Protein ALP1-like (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) NA GO:0000118; GO:0004518; GO:0046872 20462 XM_044329174.1 202 0 126 176 0 Q9P1Y6 1.2e-37 PHD and RING finger domain-containing protein 1 Homo sapiens (Human) mRNA processing [GO:0006397]; transcription by RNA polymerase II [GO:0006366] GO:0006366; GO:0006397; GO:0016020; GO:0019904; GO:0046872; GO:0070063 20463 XM_044329124.1 56 33 0 0 12 NA NA NA NA NA NA 20464 XM_029325002.2 500 1002 199 2010 440 Q9U9L2 3.97e-153 60S ribosomal protein L8 Anopheles gambiae (African malaria mosquito) cytoplasmic translation [GO:0002181] GO:0002181; GO:0003723; GO:0003735; GO:0019843; GO:0022625 20465 XM_029339520.2 288 185 97 51 111 NA NA NA NA NA NA 20466 XM_029356360.2 347 206 111 422 1575 P26630 8.21e-91 Paired box protein Pax-6 (Pax[Zf-a]) Danio rerio (Zebrafish) (Brachydanio rerio) anatomical structure development [GO:0048856]; anterior/posterior pattern specification [GO:0009952]; epithalamus development [GO:0021538]; forebrain development [GO:0030900]; habenula development [GO:0021986]; hindbrain development [GO:0030902]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression [GO:0010468]; regulation of transcription by RNA polymerase II [GO:0006357]; retinal cone cell differentiation [GO:0042670]; retinal rod cell differentiation [GO:0060221] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0008284; GO:0009952; GO:0010468; GO:0021538; GO:0021986; GO:0030900; GO:0030902; GO:0042670; GO:0043565; GO:0045944; GO:0048856; GO:0060221 20467 XM_044310066.1 0 11 3 0 1 NA NA NA NA NA NA 20468 XM_044329053.1 16 34 38 19 48 Q22875 4.13e-40 Leucine-rich repeat protein soc-2 (Suppressor of Clr protein 2) (Suppressor of activated let-60 Ras protein 8) Caenorhabditis elegans fibroblast growth factor receptor signaling pathway [GO:0008543]; muscle organ development [GO:0007517]; positive regulation of Ras protein signal transduction [GO:0046579]; regulation of cell projection organization [GO:0031344]; signal transduction [GO:0007165]; vulval development [GO:0040025] GO:0007165; GO:0007517; GO:0008543; GO:0031267; GO:0031344; GO:0040025; GO:0046579 20469 XM_029358261.2 0 0 70 37 28 NA NA NA NA NA NA 20470 XM_044320847.1 656 344 428 615 517 NA NA NA NA NA NA 20471 XM_044323591.1 34 24 4 129 232 NA NA NA NA NA NA 20472 XM_029335314.2 1697 976 920 1365 965 Q26636 2.94e-129 Cathepsin L (EC 3.4.22.15) [Cleaved into: Cathepsin L heavy chain; Cathepsin L light chain] Sarcophaga peregrina (Flesh fly) (Boettcherisca peregrina) cell differentiation [GO:0030154]; proteolysis [GO:0006508] GO:0004197; GO:0005764; GO:0006508; GO:0030154 20473 XM_029327048.2 233 153 184 232 470 Q8BX17 0 Gem-associated protein 5 (Gemin5) Mus musculus (Mouse) regulation of translation [GO:0006417]; spliceosomal snRNP assembly [GO:0000387]; translation [GO:0006412] GO:0000340; GO:0000387; GO:0003723; GO:0003730; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006412; GO:0006417; GO:0016604; GO:0017069; GO:0030619; GO:0030621; GO:0030622; GO:0032797; GO:0034718; GO:0034719; GO:0043022; GO:0097504 20474 XM_029333983.2 161 85 124 182 229 Q07326 2.41e-27 Phosphatidylinositol-glycan biosynthesis class F protein (PIG-F) (GPI11 homolog) Homo sapiens (Human) GPI anchor biosynthetic process [GO:0006506] GO:0004307; GO:0005789; GO:0006506; GO:0051377 20475 XM_029357470.2 822 379 421 395 565 B0BNE2 1.59e-128 DNA-directed RNA polymerases I, II, and III subunit RPABC1 (RNA polymerases I, II, and III subunit ABC1) (DNA-directed RNA polymerase II subunit E) (RPB5 homolog) Rattus norvegicus (Rat) transcription by RNA polymerase II [GO:0006366] GO:0003677; GO:0003899; GO:0005634; GO:0005665; GO:0005666; GO:0005736; GO:0006366; GO:1990062 20476 XM_044313462.1 2 1 18 4 160 Q9VBW3 9.84e-60 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 20477 XR_006396648.1 9 25 13 20 39 NA NA NA NA NA NA 20478 XM_029331173.2 1893 1805 1221 1296 1443 NA NA NA NA NA NA 20479 XM_029348316.2 0 8 0 0 9 NA NA NA NA NA NA 20480 XM_044310006.1 118 55 32 52 13 P16157 7.02e-48 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 20481 XM_044310006.1 118 55 32 52 13 P16157 1.59e-44 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 20482 XM_044310006.1 118 55 32 52 13 P16157 8.14e-42 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 20483 XM_044310006.1 118 55 32 52 13 P16157 1.77e-34 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 20484 XM_044310006.1 118 55 32 52 13 P16157 1.18e-26 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 20485 XM_029338752.2 3986 6959 2026 4421 3063 P79733 0 Ribonucleoside-diphosphate reductase subunit M2 (EC 1.17.4.1) (Ribonucleotide reductase protein R2 class I) (Ribonucleotide reductase small chain) (Ribonucleotide reductase small subunit) Danio rerio (Zebrafish) (Brachydanio rerio) deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260] GO:0004748; GO:0005829; GO:0006260; GO:0009263; GO:0046872 20486 XM_044321695.1 108 188 0 0 540 Q63415 4.32e-112 Proprotein convertase subtilisin/kexin type 6 (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin-like proprotein convertase 4) (SPC4) (Subtilisin/kexin-like protease PACE4) Rattus norvegicus (Rat) determination of left/right symmetry [GO:0007368]; glycoprotein metabolic process [GO:0009100]; nerve growth factor production [GO:0032902]; peptide hormone processing [GO:0016486]; protein processing [GO:0016485]; secretion by cell [GO:0032940]; zygotic determination of anterior/posterior axis, embryo [GO:0007354] GO:0004175; GO:0004252; GO:0005615; GO:0007354; GO:0007368; GO:0008201; GO:0009100; GO:0009986; GO:0016020; GO:0016485; GO:0016486; GO:0032902; GO:0032940; GO:0048406; GO:0062023 20487 XM_044307638.1 12 0 7 0 17 P98092 1.45e-26 Hemocytin (Humoral lectin) Bombyx mori (Silk moth) cell adhesion [GO:0007155] GO:0007155; GO:0030246 20488 XM_044320889.1 383 9 0 0 0 Q5JL96 2.03e-29 Probable E3 ubiquitin-protein ligase RZFP34 (EC 2.3.2.27) (OsRFP1) (RING zinc-finger protein 34) (OsRZFP34) Oryza sativa subsp. japonica (Rice) protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0005634; GO:0006511; GO:0008270; GO:0016567; GO:0061630 20489 XM_029334088.2 402 243 202 175 69 NA NA NA NA NA NA 20490 XM_044309957.1 274 163 226 171 163 P23468 2.63e-43 Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48) Homo sapiens (Human) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; neuron differentiation [GO:0030182]; phosphate-containing compound metabolic process [GO:0006796]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse assembly [GO:0051965]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; regulation of immune response [GO:0050776]; regulation of postsynaptic density assembly [GO:0099151]; synaptic membrane adhesion [GO:0099560]; trans-synaptic signaling by trans-synaptic complex [GO:0099545]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185] GO:0004725; GO:0005001; GO:0005102; GO:0005886; GO:0006470; GO:0006796; GO:0007157; GO:0007185; GO:0030182; GO:0042734; GO:0046426; GO:0050775; GO:0050776; GO:0050804; GO:0050839; GO:0051965; GO:0070062; GO:0097105; GO:0098685; GO:0098686; GO:0098978; GO:0099054; GO:0099151; GO:0099545; GO:0099560 20491 XM_044309957.1 274 163 226 171 163 P23468 1.01e-39 Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48) Homo sapiens (Human) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; neuron differentiation [GO:0030182]; phosphate-containing compound metabolic process [GO:0006796]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse assembly [GO:0051965]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; regulation of immune response [GO:0050776]; regulation of postsynaptic density assembly [GO:0099151]; synaptic membrane adhesion [GO:0099560]; trans-synaptic signaling by trans-synaptic complex [GO:0099545]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185] GO:0004725; GO:0005001; GO:0005102; GO:0005886; GO:0006470; GO:0006796; GO:0007157; GO:0007185; GO:0030182; GO:0042734; GO:0046426; GO:0050775; GO:0050776; GO:0050804; GO:0050839; GO:0051965; GO:0070062; GO:0097105; GO:0098685; GO:0098686; GO:0098978; GO:0099054; GO:0099151; GO:0099545; GO:0099560 20492 XM_044309957.1 274 163 226 171 163 P23468 1.22e-28 Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48) Homo sapiens (Human) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; neuron differentiation [GO:0030182]; phosphate-containing compound metabolic process [GO:0006796]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse assembly [GO:0051965]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; regulation of immune response [GO:0050776]; regulation of postsynaptic density assembly [GO:0099151]; synaptic membrane adhesion [GO:0099560]; trans-synaptic signaling by trans-synaptic complex [GO:0099545]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185] GO:0004725; GO:0005001; GO:0005102; GO:0005886; GO:0006470; GO:0006796; GO:0007157; GO:0007185; GO:0030182; GO:0042734; GO:0046426; GO:0050775; GO:0050776; GO:0050804; GO:0050839; GO:0051965; GO:0070062; GO:0097105; GO:0098685; GO:0098686; GO:0098978; GO:0099054; GO:0099151; GO:0099545; GO:0099560 20493 XM_044309957.1 274 163 226 171 163 P23468 2.97e-28 Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48) Homo sapiens (Human) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; neuron differentiation [GO:0030182]; phosphate-containing compound metabolic process [GO:0006796]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse assembly [GO:0051965]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; regulation of immune response [GO:0050776]; regulation of postsynaptic density assembly [GO:0099151]; synaptic membrane adhesion [GO:0099560]; trans-synaptic signaling by trans-synaptic complex [GO:0099545]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185] GO:0004725; GO:0005001; GO:0005102; GO:0005886; GO:0006470; GO:0006796; GO:0007157; GO:0007185; GO:0030182; GO:0042734; GO:0046426; GO:0050775; GO:0050776; GO:0050804; GO:0050839; GO:0051965; GO:0070062; GO:0097105; GO:0098685; GO:0098686; GO:0098978; GO:0099054; GO:0099151; GO:0099545; GO:0099560 20494 XM_044314527.1 71 16 38 34 125 NA NA NA NA NA NA 20495 XR_006391878.1 162 153 14 131 121 NA NA NA NA NA NA 20496 XM_029351453.2 1042 696 465 566 1143 Q5RBT3 0 N-alpha-acetyltransferase 35, NatC auxiliary subunit (Protein MAK10 homolog) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) N-terminal peptidyl-methionine acetylation [GO:0017196]; negative regulation of apoptotic process [GO:0043066]; smooth muscle cell proliferation [GO:0048659] GO:0005654; GO:0005737; GO:0005829; GO:0005844; GO:0005886; GO:0017196; GO:0031417; GO:0043066; GO:0048659 20497 XM_044309961.1 30 36 41 30 69 NA NA NA NA NA NA 20498 XM_044315517.1 0 0 0 9 6 NA NA NA NA NA NA 20499 XR_006394032.1 10 139 27 21 0 NA NA NA NA NA NA 20500 XM_044317711.1 4 0 0 171 0 NA NA NA NA NA NA 20501 XM_044306872.1 0 0 50 281 0 Q15858 0 Sodium channel protein type 9 subunit alpha (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1) (PN1) (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) Homo sapiens (Human) behavioral response to formalin induced pain [GO:0061368]; circadian rhythm [GO:0007623]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; inflammatory response [GO:0006954]; membrane depolarization during action potential [GO:0086010]; negative regulation of action potential [GO:0045759]; neuronal action potential [GO:0019228]; post-embryonic development [GO:0009791]; regulation of ion transmembrane transport [GO:0034765]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to toxic substance [GO:0009636]; sensory perception of pain [GO:0019233]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814] GO:0001518; GO:0005244; GO:0005248; GO:0005886; GO:0006814; GO:0006954; GO:0007623; GO:0009408; GO:0009409; GO:0009636; GO:0009791; GO:0019228; GO:0019233; GO:0030424; GO:0031402; GO:0034765; GO:0035725; GO:0045759; GO:0050965; GO:0050974; GO:0061368; GO:0086010 20502 XM_044306872.1 0 0 50 281 0 Q15858 1.48e-67 Sodium channel protein type 9 subunit alpha (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1) (PN1) (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) Homo sapiens (Human) behavioral response to formalin induced pain [GO:0061368]; circadian rhythm [GO:0007623]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; inflammatory response [GO:0006954]; membrane depolarization during action potential [GO:0086010]; negative regulation of action potential [GO:0045759]; neuronal action potential [GO:0019228]; post-embryonic development [GO:0009791]; regulation of ion transmembrane transport [GO:0034765]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to toxic substance [GO:0009636]; sensory perception of pain [GO:0019233]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814] GO:0001518; GO:0005244; GO:0005248; GO:0005886; GO:0006814; GO:0006954; GO:0007623; GO:0009408; GO:0009409; GO:0009636; GO:0009791; GO:0019228; GO:0019233; GO:0030424; GO:0031402; GO:0034765; GO:0035725; GO:0045759; GO:0050965; GO:0050974; GO:0061368; GO:0086010 20503 XM_029331200.2 10 18 20 18 24 NA NA NA NA NA NA 20504 XR_003826047.2 32 61 30 28 33 NA NA NA NA NA NA 20505 XM_044309414.1 0 0 13 0 0 NA NA NA NA NA NA 20506 XM_029348919.2 15 21 64 130 20 B8VIU6 9.73e-53 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 20507 XM_029342254.2 7618 8803 4824 9026 7405 Q6PHY8 1.61e-35 Thioredoxin reductase-like selenoprotein T1b (EC 1.8.1.9) Danio rerio (Zebrafish) (Brachydanio rerio) cell redox homeostasis [GO:0045454] GO:0004791; GO:0005789; GO:0045454 20508 XM_029340233.2 589 402 287 298 434 O19094 2.18e-165 Peroxisomal carnitine O-octanoyltransferase (COT) (EC 2.3.1.137) Bos taurus (Bovine) carnitine metabolic process [GO:0009437]; coenzyme A metabolic process [GO:0015936]; fatty acid beta-oxidation [GO:0006635]; fatty acid metabolic process [GO:0006631]; generation of precursor metabolites and energy [GO:0006091]; medium-chain fatty acid metabolic process [GO:0051791] GO:0005777; GO:0006091; GO:0006631; GO:0006635; GO:0008458; GO:0009437; GO:0015936; GO:0051791 20509 XM_044315077.1 0 0 13 0 31 NA NA NA NA NA NA 20510 XR_003827073.2 798 1061 485 1020 409 NA NA NA NA NA NA 20511 XM_029356329.2 25 0 0 27 0 NA NA NA NA NA NA 20512 XM_044319311.1 536 404 92 154 79 Q98925 5.92e-28 Interferon regulatory factor 2 (IRF-2) Gallus gallus (Chicken) immune system process [GO:0002376]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0002376; GO:0005634; GO:0006357 20513 XM_029339821.2 39 31 28 49 67 NA NA NA NA NA NA 20514 XM_029329449.2 712 457 561 689 666 A1L2I9 6.69e-64 Transmembrane protein 214-B Xenopus laevis (African clawed frog) apoptotic process [GO:0006915] GO:0005789; GO:0006915 20515 XM_029341478.2 1885 737 1300 1039 1289 Q6CLN9 1.11e-31 Protein BTN1 Kluyveromyces lactis (Yeast) (Candida sphaerica) amino acid transport [GO:0006865] GO:0005774; GO:0006865 20516 XM_044313926.1 0 51 0 0 0 NA NA NA NA NA NA 20517 XM_029347786.2 904 1566 612 1266 1209 Q7TSU0 1.75e-35 Nuclear nucleic acid-binding protein C1D Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) apoptotic process [GO:0006915]; rRNA processing [GO:0006364] GO:0003677; GO:0003723; GO:0005730; GO:0005737; GO:0006364; GO:0006915 20518 XM_029338189.2 2443 2027 1376 1389 1629 Q7T3A4 4.53e-32 Ras-related protein Rab-13 Danio rerio (Zebrafish) (Brachydanio rerio) angiogenesis [GO:0001525]; bicellular tight junction assembly [GO:0070830]; cellular response to insulin stimulus [GO:0032869]; cortical actin cytoskeleton organization [GO:0030866]; endocytic recycling [GO:0032456]; endothelial cell chemotaxis [GO:0035767]; Golgi vesicle fusion to target membrane [GO:0048210]; neuron projection development [GO:0031175]; protein kinase A signaling [GO:0010737]; protein localization to cell leading edge [GO:1902463]; protein localization to plasma membrane [GO:0072659]; protein secretion [GO:0009306]; regulation of exocytosis [GO:0017157]; trans-Golgi network to recycling endosome transport [GO:0044795]; vesicle docking involved in exocytosis [GO:0006904] GO:0001525; GO:0003924; GO:0005525; GO:0005768; GO:0005802; GO:0005886; GO:0005923; GO:0006904; GO:0008021; GO:0009306; GO:0010737; GO:0016328; GO:0017157; GO:0030027; GO:0030139; GO:0030140; GO:0030866; GO:0031175; GO:0031410; GO:0032456; GO:0032593; GO:0032869; GO:0035767; GO:0043005; GO:0043231; GO:0044795; GO:0048210; GO:0055037; GO:0055038; GO:0070830; GO:0072659; GO:1902463 20519 XM_044316443.1 60 11 11 5 50 NA NA NA NA NA NA 20520 XM_044328288.1 324 254 187 325 168 NA NA NA NA NA NA 20521 XM_044314682.1 91 151 13 36 91 NA NA NA NA NA NA 20522 XM_044320305.1 107 99 22 99 31 Q9TU53 9.85e-89 Cubilin Canis lupus familiaris (Dog) (Canis familiaris) cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031] GO:0005509; GO:0005765; GO:0005768; GO:0005905; GO:0008203; GO:0015031; GO:0016324; GO:0031419; GO:0031526; GO:0043235 20523 XM_044320305.1 107 99 22 99 31 Q9TU53 3.94e-80 Cubilin Canis lupus familiaris (Dog) (Canis familiaris) cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031] GO:0005509; GO:0005765; GO:0005768; GO:0005905; GO:0008203; GO:0015031; GO:0016324; GO:0031419; GO:0031526; GO:0043235 20524 XM_044320305.1 107 99 22 99 31 Q9TU53 1.27e-77 Cubilin Canis lupus familiaris (Dog) (Canis familiaris) cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031] GO:0005509; GO:0005765; GO:0005768; GO:0005905; GO:0008203; GO:0015031; GO:0016324; GO:0031419; GO:0031526; GO:0043235 20525 XM_044320305.1 107 99 22 99 31 Q9TU53 4.03e-74 Cubilin Canis lupus familiaris (Dog) (Canis familiaris) cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031] GO:0005509; GO:0005765; GO:0005768; GO:0005905; GO:0008203; GO:0015031; GO:0016324; GO:0031419; GO:0031526; GO:0043235 20526 XM_044320305.1 107 99 22 99 31 Q9TU53 8.49e-58 Cubilin Canis lupus familiaris (Dog) (Canis familiaris) cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031] GO:0005509; GO:0005765; GO:0005768; GO:0005905; GO:0008203; GO:0015031; GO:0016324; GO:0031419; GO:0031526; GO:0043235 20527 XM_044320305.1 107 99 22 99 31 Q9TU53 4.11e-40 Cubilin Canis lupus familiaris (Dog) (Canis familiaris) cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031] GO:0005509; GO:0005765; GO:0005768; GO:0005905; GO:0008203; GO:0015031; GO:0016324; GO:0031419; GO:0031526; GO:0043235 20528 XM_044318287.1 0 0 2 0 21 NA NA NA NA NA NA 20529 XM_044322283.1 0 0 1 102 0 Q7RTR2 1.9e-59 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20530 XM_044322283.1 0 0 1 102 0 Q7RTR2 5.22e-55 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20531 XM_044322283.1 0 0 1 102 0 Q7RTR2 1.01e-54 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20532 XM_044322283.1 0 0 1 102 0 Q7RTR2 8.84e-26 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20533 XM_044311181.1 17 3 0 0 0 NA NA NA NA NA NA 20534 XM_044327519.1 0 2 0 0 10 NA NA NA NA NA NA 20535 XM_044316832.1 93 30 0 51 0 NA NA NA NA NA NA 20536 XM_029333355.2 0 56 108 28 0 NA NA NA NA NA NA 20537 XM_044307576.1 1504 790 747 1195 1210 NA NA NA NA NA NA 20538 XM_044311949.1 7 3 7 13 24 NA NA NA NA NA NA 20539 XM_029347152.2 17 19 28 17 25 NA NA NA NA NA NA 20540 XM_044318057.1 12547 11436 6148 11460 10704 Q68FD5 0 Clathrin heavy chain 1 Mus musculus (Mouse) amyloid-beta clearance by transcytosis [GO:0150093]; autophagy [GO:0006914]; cell division [GO:0051301]; clathrin coat assembly [GO:0048268]; clathrin-dependent endocytosis [GO:0072583]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886]; mitotic cell cycle [GO:0000278]; mitotic spindle assembly [GO:0090307]; negative regulation of hyaluronan biosynthetic process [GO:1900126]; negative regulation of protein localization to plasma membrane [GO:1903077]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of mitotic spindle organization [GO:0060236]; retrograde transport, endosome to Golgi [GO:0042147]; synaptic vesicle endocytosis [GO:0048488]; transferrin transport [GO:0033572] GO:0000278; GO:0003725; GO:0005198; GO:0005739; GO:0005764; GO:0005768; GO:0005819; GO:0005829; GO:0005905; GO:0006886; GO:0006898; GO:0006914; GO:0007030; GO:0008022; GO:0016020; GO:0019901; GO:0030117; GO:0030118; GO:0030130; GO:0030132; GO:0030136; GO:0030315; GO:0030506; GO:0031072; GO:0031523; GO:0031623; GO:0032051; GO:0032991; GO:0033572; GO:0042147; GO:0042277; GO:0042383; GO:0042470; GO:0043209; GO:0045334; GO:0048268; GO:0048488; GO:0050750; GO:0051301; GO:0060236; GO:0071439; GO:0072583; GO:0072686; GO:0090307; GO:0097718; GO:0098684; GO:0098835; GO:0098850; GO:0120283; GO:0150093; GO:1900126; GO:1903077; GO:1990381; GO:1990498 20541 XM_044311340.1 0 0 2 0 30 NA NA NA NA NA NA 20542 XM_029333117.2 8 39 42 56 53 NA NA NA NA NA NA 20543 XM_029336442.2 3899 4962 2281 3336 2509 Q08BA6 2.61e-92 RNA demethylase ALKBH5 (EC 1.14.11.53) (Alkylated DNA repair protein alkB homolog 5) (Alpha-ketoglutarate-dependent dioxygenase alkB homolog 5) Danio rerio (Zebrafish) (Brachydanio rerio) mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; oxidative single-stranded RNA demethylation [GO:0035553]; response to hypoxia [GO:0001666]; spermatogenesis [GO:0007283] GO:0001666; GO:0005634; GO:0006397; GO:0006406; GO:0007283; GO:0016607; GO:0016706; GO:0035515; GO:0035553; GO:0046872; GO:1990931 20544 XM_029346105.2 11806 7519 5665 13283 4339 Q9Y5R2 4.27e-92 Matrix metalloproteinase-24 (MMP-24) (EC 3.4.24.-) (Membrane-type matrix metalloproteinase 5) (MT-MMP 5) (MTMMP5) (Membrane-type-5 matrix metalloproteinase) (MT5-MMP) (MT5MMP) [Cleaved into: Processed matrix metalloproteinase-24] Homo sapiens (Human) cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; collagen catabolic process [GO:0030574]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; extracellular matrix organization [GO:0030198]; glial cell differentiation [GO:0010001]; neuronal stem cell population maintenance [GO:0097150]; proteolysis [GO:0006508] GO:0004222; GO:0005886; GO:0006508; GO:0008047; GO:0008270; GO:0010001; GO:0030198; GO:0030574; GO:0031012; GO:0032588; GO:0044331; GO:0045296; GO:0050965; GO:0070062; GO:0097150; GO:0098742 20545 XM_044329141.1 11 0 17 65 41 P21265 0 Adenylosuccinate lyase (ADSL) (ASL) (EC 4.3.2.2) (Adenylosuccinase) (ASase) Gallus gallus (Chicken) 'de novo' AMP biosynthetic process [GO:0044208]; 'de novo' IMP biosynthetic process [GO:0006189]; 'de novo' XMP biosynthetic process [GO:0097294]; AMP salvage [GO:0044209]; GMP biosynthetic process [GO:0006177] GO:0004018; GO:0005829; GO:0006177; GO:0006189; GO:0032991; GO:0042802; GO:0044208; GO:0044209; GO:0070626; GO:0097294 20546 XR_006396957.1 12 88 16 20 35 NA NA NA NA NA NA 20547 XM_029356656.2 3 5 9 3 45 NA NA NA NA NA NA 20548 XM_044310486.1 29 0 16 192 223 NA NA NA NA NA NA 20549 XM_044313553.1 21 0 0 20 10 O64411 2.15e-67 Polyamine oxidase 1 (EC 1.5.3.14) (EC 1.5.3.15) Zea mays (Maize) polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208] GO:0006598; GO:0009505; GO:0016491; GO:0046208; GO:0046592; GO:0048046; GO:0050660; GO:0052893; GO:0052896; GO:0052897; GO:0052900 20550 XM_044315364.1 0 0 0 16 0 NA NA NA NA NA NA 20551 XM_044309298.1 16 12 28 0 46 NA NA NA NA NA NA 20552 XR_006391317.1 57 2 9 3 43 NA NA NA NA NA NA 20553 XM_029347632.2 97 49 29 103 78 NA NA NA NA NA NA 20554 XM_044327812.1 166 88 0 14 0 NA NA NA NA NA NA 20555 XM_044306992.1 12 20 22 2 178 NA NA NA NA NA NA 20556 XM_029338762.2 66 81 95 89 172 NA NA NA NA NA NA 20557 XM_029344403.2 20 8 10 8 31 Q91770 1e-25 Homeobox protein not2 (Xnot-2) (Xnot2) Xenopus laevis (African clawed frog) negative regulation of DNA-templated transcription [GO:0045892]; notochord formation [GO:0014028] GO:0000981; GO:0003677; GO:0005634; GO:0014028; GO:0045892 20558 XM_029358194.2 11640 10237 8684 16390 17796 P15311 3.89e-158 Ezrin (Cytovillin) (Villin-2) (p81) Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; astral microtubule organization [GO:0030953]; cellular response to cAMP [GO:0071320]; cortical microtubule organization [GO:0043622]; establishment of centrosome localization [GO:0051660]; establishment of endothelial barrier [GO:0061028]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; filopodium assembly [GO:0046847]; intestinal D-glucose absorption [GO:0001951]; leukocyte cell-cell adhesion [GO:0007159]; membrane to membrane docking [GO:0022614]; microvillus assembly [GO:0030033]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of gene expression [GO:0010628]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein secretion [GO:0050714]; postsynaptic actin cytoskeleton organization [GO:0098974]; protein kinase A signaling [GO:0010737]; protein localization to cell cortex [GO:0072697]; protein localization to plasma membrane [GO:0072659]; protein-containing complex localization [GO:0031503]; receptor internalization [GO:0031623]; regulation of cell shape [GO:0008360]; regulation of microvillus length [GO:0032532]; regulation of organelle assembly [GO:1902115]; sphingosine-1-phosphate receptor signaling pathway [GO:0003376]; terminal web assembly [GO:1902896] GO:0000122; GO:0001650; GO:0001726; GO:0001772; GO:0001931; GO:0001951; GO:0003376; GO:0003723; GO:0003779; GO:0005615; GO:0005737; GO:0005768; GO:0005829; GO:0005884; GO:0005886; GO:0005902; GO:0005903; GO:0005912; GO:0005925; GO:0007159; GO:0008017; GO:0008022; GO:0008360; GO:0010628; GO:0010737; GO:0015629; GO:0016020; GO:0016323; GO:0016324; GO:0019898; GO:0019904; GO:0022614; GO:0030033; GO:0030175; GO:0030863; GO:0030953; GO:0031503; GO:0031528; GO:0031532; GO:0031623; GO:0031982; GO:0032532; GO:0032587; GO:0032703; GO:0032991; GO:0034236; GO:0034237; GO:0035088; GO:0036064; GO:0040018; GO:0042802; GO:0042995; GO:0043622; GO:0044548; GO:0044853; GO:0045177; GO:0045296; GO:0045732; GO:0046847; GO:0048015; GO:0048471; GO:0050714; GO:0050839; GO:0050860; GO:0051015; GO:0051017; GO:0051018; GO:0051117; GO:0051660; GO:0061028; GO:0070062; GO:0070373; GO:0071320; GO:0071944; GO:0072659; GO:0072697; GO:0097718; GO:0098592; GO:0098974; GO:1902115; GO:1902896; GO:1902966; GO:1903078; GO:1903753; GO:2000643 20559 XM_029334629.2 137 170 158 174 150 Q8IY33 1.48e-36 MICAL-like protein 2 (Junctional Rab13-binding protein) (Molecule interacting with CasL-like 2) (MICAL-L2) Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; actin filament polymerization [GO:0030041]; bicellular tight junction assembly [GO:0070830]; endocytic recycling [GO:0032456]; neuron projection development [GO:0031175]; positive regulation of protein targeting to mitochondrion [GO:1903955]; substrate adhesion-dependent cell spreading [GO:0034446] GO:0001725; GO:0005829; GO:0005886; GO:0005911; GO:0005923; GO:0030041; GO:0031005; GO:0031175; GO:0031267; GO:0031532; GO:0032456; GO:0034446; GO:0042805; GO:0043005; GO:0046872; GO:0051015; GO:0055037; GO:0070830; GO:1903955 20560 XM_029357880.2 42 27 36 94 95 Q8BGC1 8.85e-86 UPF0489 protein C5orf22 homolog Mus musculus (Mouse) NA NA 20561 XM_044318883.1 276 258 0 237 0 B1WAR9 9.19e-65 Serine/threonine-protein kinase greatwall (GW) (GWL) (EC 2.7.11.1) (Microtubule-associated serine/threonine-protein kinase-like) (MAST-L) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic cell cycle [GO:0000278]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; protein phosphorylation [GO:0006468] GO:0000086; GO:0000278; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0006468; GO:0006974; GO:0032154; GO:0032515; GO:0051301; GO:0051721; GO:0106310 20562 XM_044318883.1 276 258 0 237 0 B1WAR9 1.03e-53 Serine/threonine-protein kinase greatwall (GW) (GWL) (EC 2.7.11.1) (Microtubule-associated serine/threonine-protein kinase-like) (MAST-L) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic cell cycle [GO:0000278]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; protein phosphorylation [GO:0006468] GO:0000086; GO:0000278; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0006468; GO:0006974; GO:0032154; GO:0032515; GO:0051301; GO:0051721; GO:0106310 20563 XM_029357441.2 28 256 6 19 31 A7Z056 0 Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.4.19.12) (Deubiquitinating enzyme 20) (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20) Bos taurus (Bovine) endocytosis [GO:0006897]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0001664; GO:0004197; GO:0004843; GO:0005737; GO:0005813; GO:0006511; GO:0006897; GO:0008270; GO:0008277; GO:0016579; GO:0048471; GO:0070536; GO:0071108 20564 XM_044308304.1 17 15 12 0 229 NA NA NA NA NA NA 20565 XM_044318508.1 1150 1126 526 1119 997 NA NA NA NA NA NA 20566 XM_044321494.1 0 138 361 521 460 Q01804 9.52e-72 OTU domain-containing protein 4 (EC 3.4.19.12) (HIV-1-induced protein HIN-1) Homo sapiens (Human) innate immune response [GO:0045087]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; positive regulation of DNA demethylation [GO:1901537]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; regulation of protein K48-linked deubiquitination [GO:1903093] GO:0003723; GO:0004843; GO:0005634; GO:0005829; GO:0016579; GO:0034122; GO:0045087; GO:0060090; GO:0061578; GO:0070536; GO:0071108; GO:1901537; GO:1903093; GO:2000660 20567 XM_029329724.2 59 19 33 7 76 NA NA NA NA NA NA 20568 XM_044328331.1 1271 1122 634 796 1098 B3CQD1 3.7e-116 Peptide chain release factor 1 (RF-1) Orientia tsutsugamushi (strain Ikeda) (Rickettsia tsutsugamushi) NA GO:0005737; GO:0016149 20569 XM_044308641.1 5 0 20 427 181 NA NA NA NA NA NA 20570 XM_029344292.2 579 455 267 399 411 F4INN2 7.56e-26 Gamma-glutamyl peptidase 4 (EC 3.4.19.-) Arabidopsis thaliana (Mouse-ear cress) proteolysis [GO:0006508] GO:0005829; GO:0006508; GO:0008233 20571 XM_044315460.1 94 31 66 83 78 NA NA NA NA NA NA 20572 XM_044313213.1 466 301 329 1455 350 P13908 1.2e-60 Neuronal acetylcholine receptor subunit non-alpha-2 (GFN-alpha-2) Carassius auratus (Goldfish) NA GO:0004888; GO:0022848; GO:0045211 20573 XM_044319129.1 293 103 44 107 90 Q9MYW0 1.76e-92 Short transient receptor potential channel 6 (TrpC6) Bos taurus (Bovine) calcium ion transmembrane transport [GO:0070588]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of ion transmembrane transporter activity [GO:0032414]; regulation of cytosolic calcium ion concentration [GO:0051480]; single fertilization [GO:0007338] GO:0005261; GO:0005737; GO:0005886; GO:0007204; GO:0007338; GO:0015279; GO:0032414; GO:0034703; GO:0036057; GO:0042803; GO:0051480; GO:0051928; GO:0070588; GO:0070679 20574 XM_044319822.1 36 2 9 4 12 NA NA NA NA NA NA 20575 XM_029326984.2 1342 959 791 1245 1134 Q75UQ2 1.9e-34 Craniofacial development protein 1 (Bucentaur) Rattus norvegicus (Rat) cell adhesion [GO:0007155]; chromatin remodeling [GO:0006338]; fibroblast apoptotic process [GO:0044346]; negative regulation of fibroblast apoptotic process [GO:2000270]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360] GO:0000776; GO:0000812; GO:0005634; GO:0006338; GO:0007155; GO:0008360; GO:0042127; GO:0044346; GO:2000270 20576 XM_029352972.2 326 109 197 391 217 Q17RS7 6.59e-69 Flap endonuclease GEN homolog 1 (EC 3.1.-.-) Homo sapiens (Human) double-strand break repair via homologous recombination [GO:0000724]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; regulation of centrosome duplication [GO:0010824]; replication fork processing [GO:0031297]; resolution of mitotic recombination intermediates [GO:0071140]; resolution of recombination intermediates [GO:0071139] GO:0000287; GO:0000400; GO:0000724; GO:0005654; GO:0005813; GO:0008821; GO:0010824; GO:0017108; GO:0031297; GO:0042803; GO:0071139; GO:0071140; GO:0090267 20577 XM_029324441.2 1998 1821 1411 1889 1948 Q96I24 1.91e-71 Far upstream element-binding protein 3 (FUSE-binding protein 3) Homo sapiens (Human) DNA-templated transcription [GO:0006351]; intracellular mRNA localization [GO:0008298]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression [GO:0010468] GO:0003697; GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0005737; GO:0005840; GO:0005844; GO:0006351; GO:0008298; GO:0010468; GO:0010628; GO:0016020; GO:0043025; GO:0043198; GO:0045893; GO:0045944 20578 XM_029334844.2 30 5 9 17 0 O60678 3.71e-134 Protein arginine N-methyltransferase 3 (EC 2.1.1.319) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3) Homo sapiens (Human) dendritic spine morphogenesis [GO:0060997]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of retinoic acid biosynthetic process [GO:1900053]; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [GO:0019919]; protein methylation [GO:0006479] GO:0005737; GO:0005829; GO:0006479; GO:0008168; GO:0016274; GO:0019919; GO:0031397; GO:0035241; GO:0035242; GO:0043022; GO:0046872; GO:0060997; GO:0072341; GO:1900053 20579 XR_003827535.2 16 0 16 0 47 NA NA NA NA NA NA 20580 XM_044316252.1 16 8 44 14 18 Q9WVK8 4.86e-104 Cholesterol 24-hydroxylase (CH24H) (EC 1.14.14.25) (Cholesterol 24-monooxygenase) (Cholesterol 24S-hydroxylase) (Cytochrome P450 46A1) Mus musculus (Mouse) cholesterol catabolic process [GO:0006707]; progesterone metabolic process [GO:0042448]; protein localization to membrane raft [GO:1903044]; regulation of long-term synaptic potentiation [GO:1900271]; xenobiotic metabolic process [GO:0006805] GO:0005506; GO:0005789; GO:0006707; GO:0006805; GO:0008395; GO:0020037; GO:0030425; GO:0033781; GO:0042448; GO:0062184; GO:0098793; GO:0098794; GO:1900271; GO:1903044 20581 XR_006394879.1 0 4 0 1 11 NA NA NA NA NA NA 20582 XM_029340826.2 1728 568 721 1643 661 NA NA NA NA NA NA 20583 XM_044328515.1 55 25 31 38 65 O05218 3.32e-80 Glutathione hydrolase-like YwrD proenzyme (EC 2.3.2.2) (Putative gamma-glutamyltransferase YwrD) (EC 3.4.19.13) [Cleaved into: Glutathione hydrolase-like YwrD large chain; Glutathione hydrolase-like YwrD small chain] Bacillus subtilis (strain 168) glutathione catabolic process [GO:0006751]; proteolysis [GO:0006508] GO:0006508; GO:0006751; GO:0036374; GO:0102953; GO:0103068 20584 XR_006394585.1 287 376 228 535 401 NA NA NA NA NA NA 20585 XM_029351864.2 161 121 76 137 160 NA NA NA NA NA NA 20586 XM_029339187.2 920 603 470 723 1307 Q9Y4C0 1.34e-34 Neurexin-3 (Neurexin III-alpha) (Neurexin-3-alpha) Homo sapiens (Human) adult behavior [GO:0030534]; axon guidance [GO:0007411]; learning [GO:0007612]; neuron cell-cell adhesion [GO:0007158]; social behavior [GO:0035176]; vocalization behavior [GO:0071625] GO:0005886; GO:0007158; GO:0007411; GO:0007612; GO:0030534; GO:0035176; GO:0038023; GO:0046872; GO:0050839; GO:0071625; GO:0097109 20587 XM_044321653.1 119 169 254 134 284 Q1LZC5 2.56e-39 Ankyrin repeat domain-containing protein 54 Bos taurus (Bovine) nucleocytoplasmic transport [GO:0006913]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of intracellular signal transduction [GO:1902531]; regulation of protein kinase activity [GO:0045859] GO:0005634; GO:0005737; GO:0006913; GO:0019887; GO:0030496; GO:0044877; GO:0045648; GO:0045859; GO:1902531 20588 XM_044325130.1 1039 806 887 839 832 O95876 2.46e-172 WD repeat-containing and planar cell polarity effector protein fritz homolog (hFRTZ) (Bardet-Biedl syndrome 15 protein) (WD repeat-containing and planar cell polarity effector protein) Homo sapiens (Human) auditory receptor cell morphogenesis [GO:0002093]; camera-type eye development [GO:0043010]; cilium assembly [GO:0060271]; cilium organization [GO:0044782]; circulatory system development [GO:0072359]; digestive system development [GO:0055123]; embryonic digit morphogenesis [GO:0042733]; establishment of planar polarity [GO:0001736]; establishment of protein localization [GO:0045184]; intraciliary transport [GO:0042073]; kidney development [GO:0001822]; nervous system development [GO:0007399]; neural tube development [GO:0021915]; podocyte cell migration [GO:0090521]; regulation of cilium assembly [GO:1902017]; regulation of embryonic cell shape [GO:0016476]; regulation of establishment of cell polarity [GO:2000114]; regulation of fibroblast migration [GO:0010762]; regulation of focal adhesion assembly [GO:0051893]; regulation of protein localization [GO:0032880]; regulation of ruffle assembly [GO:1900027]; respiratory system development [GO:0060541]; roof of mouth development [GO:0060021]; septin cytoskeleton organization [GO:0032185]; smoothened signaling pathway [GO:0007224]; tongue morphogenesis [GO:0043587] GO:0001736; GO:0001822; GO:0002093; GO:0005886; GO:0005929; GO:0005930; GO:0007224; GO:0007399; GO:0010762; GO:0016476; GO:0021915; GO:0032185; GO:0032880; GO:0042073; GO:0042733; GO:0043010; GO:0043587; GO:0044782; GO:0045184; GO:0051893; GO:0055123; GO:0060021; GO:0060271; GO:0060541; GO:0072359; GO:0090521; GO:0097541; GO:1900027; GO:1902017; GO:2000114 20589 XR_006397157.1 37 42 35 50 64 NA NA NA NA NA NA 20590 XM_044317828.1 2046 1199 1172 2228 1635 O75095 5.8e-45 Multiple epidermal growth factor-like domains protein 6 (Multiple EGF-like domains protein 6) (Epidermal growth factor-like protein 3) (EGF-like protein 3) Homo sapiens (Human) NA GO:0005509; GO:0005576 20591 XM_044317828.1 2046 1199 1172 2228 1635 O75095 1.14e-30 Multiple epidermal growth factor-like domains protein 6 (Multiple EGF-like domains protein 6) (Epidermal growth factor-like protein 3) (EGF-like protein 3) Homo sapiens (Human) NA GO:0005509; GO:0005576 20592 XM_029336249.2 5232 4844 2896 5189 3485 Q58DN3 3.14e-77 Tetraspanin-17 (Tspan-17) Bos taurus (Bovine) protein localization to plasma membrane [GO:0072659]; protein maturation [GO:0051604] GO:0005886; GO:0051604; GO:0072659 20593 XM_044313967.1 24 7 10 17 12 NA NA NA NA NA NA 20594 XM_044326548.1 27 14 16 3 43 NA NA NA NA NA NA 20595 XM_029349364.2 1625 917 714 1427 1360 Q9Y597 0 BTB/POZ domain-containing protein KCTD3 (Renal carcinoma antigen NY-REN-45) Homo sapiens (Human) protein homooligomerization [GO:0051260] GO:0005886; GO:0051260 20596 XM_044311822.1 3 0 21 36 15 NA NA NA NA NA NA 20597 XM_029356904.2 58 51 72 69 133 Q6DCE8 7.28e-147 Cationic amino acid transporter 2 (CAT-2) (CAT2) (Low affinity cationic amino acid transporter 2) (Solute carrier family 7 member 2) Xenopus laevis (African clawed frog) L-arginine transmembrane transport [GO:1903826] GO:0005886; GO:0061459; GO:1903826 20598 XM_029328316.2 472 246 1105 1288 591 NA NA NA NA NA NA 20599 XM_029350937.2 2989 4318 1901 2487 2781 Q5XIU9 2.17e-39 Membrane-associated progesterone receptor component 2 Rattus norvegicus (Rat) adipose tissue development [GO:0060612]; heme transport [GO:0015886] GO:0005496; GO:0005635; GO:0005783; GO:0012505; GO:0015232; GO:0015886; GO:0016020; GO:0020037; GO:0060612 20600 XM_029346926.2 1497 1542 986 1354 1448 P51824 1.62e-84 ADP-ribosylation factor 1 (EC 3.6.5.2) Solanum tuberosum (Potato) intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192] GO:0003924; GO:0005525; GO:0005737; GO:0005794; GO:0006886; GO:0016192 20601 XR_006394517.1 191 137 165 126 283 NA NA NA NA NA NA 20602 XM_029334326.2 0 128 0 0 206 E9PUQ8 0 Diacylglycerol kinase delta (DAG kinase delta) (EC 2.7.1.107) Mus musculus (Mouse) diacylglycerol metabolic process [GO:0046339]; endocytosis [GO:0006897]; intracellular signal transduction [GO:0035556]; lipid phosphorylation [GO:0046834]; negative regulation of protein kinase C signaling [GO:0090038]; phosphatidic acid biosynthetic process [GO:0006654]; positive regulation of clathrin-dependent endocytosis [GO:2000370]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; protein transport [GO:0015031]; response to organic substance [GO:0010033] GO:0004143; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0005905; GO:0006654; GO:0006897; GO:0007205; GO:0010033; GO:0015031; GO:0019900; GO:0031410; GO:0035556; GO:0042802; GO:0042803; GO:0045742; GO:0046339; GO:0046834; GO:0046872; GO:0046982; GO:0090038; GO:2000370 20603 XM_044318434.1 15 26 24 25 87 NA NA NA NA NA NA 20604 XM_044312139.1 47 9 37 108 9 NA NA NA NA NA NA 20605 XM_044321308.1 20 0 7 3 0 NA NA NA NA NA NA 20606 XM_044310327.1 11 100 62 79 121 NA NA NA NA NA NA 20607 XM_044307218.1 782 438 432 1687 9 NA NA NA NA NA NA 20608 XM_029356678.2 2398 1360 1422 2115 2444 Q801X6 2.32e-60 Phosphatase and actin regulator 1 Gallus gallus (Chicken) actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actomyosin structure organization [GO:0031032]; cell motility [GO:0048870]; stress fiber assembly [GO:0043149] GO:0003779; GO:0004864; GO:0005634; GO:0005829; GO:0030036; GO:0031032; GO:0031532; GO:0043149; GO:0045202; GO:0048870 20609 XM_044316000.1 1 0 3 2 11 NA NA NA NA NA NA 20610 XM_044326516.1 0 0 2 0 8 NA NA NA NA NA NA 20611 XM_044326865.1 792 502 428 981 789 NA NA NA NA NA NA 20612 XM_044322777.1 132 87 262 237 540 Q86SG6 1.04e-125 Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never in mitosis A-related kinase 8) (NimA-related protein kinase 8) (Nima-related protein kinase 12a) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; chromosome segregation [GO:0007059]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; protein phosphorylation [GO:0006468]; regulation of hippo signaling [GO:0035330] GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005929; GO:0006468; GO:0007059; GO:0007368; GO:0007507; GO:0009887; GO:0035330; GO:0046872; GO:0097543; GO:0097546; GO:0106310 20613 XR_003824246.2 115 37 146 82 35 NA NA NA NA NA NA 20614 XR_006394444.1 10 7 14 1 73 NA NA NA NA NA NA 20615 XM_029354021.2 57 16 18 47 7 P42291 7.44e-23 D(1C) dopamine receptor Xenopus laevis (African clawed frog) regulation of biological quality [GO:0065008] GO:0004930; GO:0005886; GO:0065008 20616 XM_044314451.1 288 48 434 311 238 P15374 6.06e-92 Ubiquitin carboxyl-terminal hydrolase isozyme L3 (UCH-L3) (EC 3.4.19.12) (Ubiquitin thioesterase L3) Homo sapiens (Human) post-translational protein modification [GO:0043687]; protein catabolic process [GO:0030163]; protein deubiquitination [GO:0016579]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004843; GO:0005654; GO:0005737; GO:0005829; GO:0006511; GO:0008233; GO:0016567; GO:0016579; GO:0019784; GO:0030163; GO:0043130; GO:0043687 20617 XM_044319405.1 2 6 24 16 80 NA NA NA NA NA NA 20618 XM_044320316.1 171 146 96 142 280 Q9TU53 5.3e-21 Cubilin Canis lupus familiaris (Dog) (Canis familiaris) cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031] GO:0005509; GO:0005765; GO:0005768; GO:0005905; GO:0008203; GO:0015031; GO:0016324; GO:0031419; GO:0031526; GO:0043235 20619 XM_029347652.2 370 162 82 619 228 A0A1B4XBH3 3.87e-155 Highly reducing polyketide synthase sdnO (EC 2.3.1.-) (Sordarin/hypoxysordarin biosynthesis cluster protein O) Sordaria araneosa (Pleurage araneosa) antibiotic biosynthetic process [GO:0017000]; organic substance biosynthetic process [GO:1901576] GO:0016491; GO:0016746; GO:0017000; GO:0031177; GO:1901576 20620 XM_029355111.2 436 1 17 0 38 NA NA NA NA NA NA 20621 XM_029351189.2 580 809 462 278 281 Q3UF25 1.47e-61 Store-operated calcium entry regulator STIMATE (STIM-activating enhancer encoded by TMEM110) (Transmembrane protein 110) Mus musculus (Mouse) activation of store-operated calcium channel activity [GO:0032237]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886] GO:0005246; GO:0005789; GO:0016020; GO:0032237; GO:0032541; GO:0035584; GO:0070886; GO:0140268 20622 XM_044307329.1 35 11 41 6 0 NA NA NA NA NA NA 20623 XR_006394159.1 14 0 2 1 68 NA NA NA NA NA NA 20624 XM_044309425.1 5957 5136 1020 3488 23 NA NA NA NA NA NA 20625 XM_029329854.2 120 103 30 81 133 NA NA NA NA NA NA 20626 XM_044319674.1 26 15 30 38 129 NA NA NA NA NA NA 20627 XM_029355603.2 252 109 116 141 275 NA NA NA NA NA NA 20628 XM_044324404.1 405 446 145 355 168 Q9NUU7 0 ATP-dependent RNA helicase DDX19A (EC 3.6.4.13) (DDX19-like protein) (DEAD box protein 19A) Homo sapiens (Human) poly(A)+ mRNA export from nucleus [GO:0016973]; positive regulation of apoptotic process [GO:0043065]; response to zinc ion [GO:0010043] GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005654; GO:0010043; GO:0010494; GO:0016020; GO:0016887; GO:0016973; GO:0043065 20629 XM_029338211.2 4950 4930 3722 4647 1883 P81628 2.06e-40 Endoplasmic reticulum resident protein 29 (ERp29) Gallus gallus (Chicken) protein secretion [GO:0009306] GO:0005783; GO:0005788; GO:0009306 20630 XM_029340487.2 239 273 149 221 229 NA NA NA NA NA NA 20631 XM_044324660.1 0 0 219 0 66 O15068 1.46e-140 Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2-transforming sequence-like protein) Homo sapiens (Human) intracellular signal transduction [GO:0035556]; positive regulation of Rho protein signal transduction [GO:0035025]; regulation of small GTPase mediated signal transduction [GO:0051056] GO:0005085; GO:0005615; GO:0005737; GO:0005829; GO:0005886; GO:0012505; GO:0019898; GO:0031234; GO:0035025; GO:0035091; GO:0035556; GO:0051056 20632 XM_029357531.2 30 56 22 83 119 NA NA NA NA NA NA 20633 XM_029329004.2 0 0 190 552 0 Q3ZBG9 5.03e-87 Phospholipid scramblase 2 (PL scramblase 2) (Ca(2+)-dependent phospholipid scramblase 2) Bos taurus (Bovine) plasma membrane phospholipid scrambling [GO:0017121] GO:0005886; GO:0017121; GO:0017128; GO:0046872 20634 XM_029334483.2 0 2924 1823 196 714 Q9VZF4 6.33e-22 F-box/WD repeat-containing protein 7 (F-box and WD-40 domain-containing protein 7) (Protein archipelago) Drosophila melanogaster (Fruit fly) branch fusion, open tracheal system [GO:0035147]; cellular response to hypoxia [GO:0071456]; DNA endoreduplication [GO:0042023]; negative regulation of cellular response to hypoxia [GO:1900038]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of growth [GO:0045926]; negative regulation of imaginal disc growth [GO:0045571]; protein ubiquitination [GO:0016567]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of exit from mitosis [GO:0007096]; regulation of mitotic nuclear division [GO:0007088]; regulation of proteolysis [GO:0030162]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; trachea development [GO:0060438]; ventral cord development [GO:0007419] GO:0005634; GO:0007088; GO:0007096; GO:0007419; GO:0016567; GO:0019005; GO:0030162; GO:0030332; GO:0031146; GO:0035147; GO:0042023; GO:0045571; GO:0045926; GO:0060253; GO:0060438; GO:0071456; GO:1900038; GO:1903146; GO:1990381 20635 XR_006393673.1 252 201 144 292 113 NA NA NA NA NA NA 20636 XM_044322282.1 411 638 431 439 451 NA NA NA NA NA NA 20637 XM_029341405.2 252 324 196 170 118 NA NA NA NA NA NA 20638 XM_044312234.1 25 8 8 10 3 NA NA NA NA NA NA 20639 XM_044310322.1 2141 1691 1147 656 612 NA NA NA NA NA NA 20640 XM_044320615.1 21 101 85 0 0 O16025 0 Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (AOS) (EC 4.2.1.-) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)] Plexaura homomalla (Black sea rod) arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; lipid oxidation [GO:0034440]; oxylipin biosynthetic process [GO:0031408] GO:0005506; GO:0005737; GO:0006633; GO:0009978; GO:0016020; GO:0019369; GO:0020037; GO:0031408; GO:0034440; GO:0047677 20641 XM_044320477.1 3497 2196 1606 3193 2612 Q8CJ40 0 Rootletin (Ciliary rootlet coiled-coil protein) Mus musculus (Mouse) cellular homeostasis [GO:0019725]; centriole-centriole cohesion [GO:0010457]; centrosome cycle [GO:0007098]; ciliary basal body organization [GO:0032053]; epithelial structure maintenance [GO:0010669]; establishment of localization in cell [GO:0051649]; establishment of organelle localization [GO:0051656]; photoreceptor cell maintenance [GO:0045494]; positive regulation of cilium assembly [GO:0045724]; positive regulation of protein localization to cilium [GO:1903566]; protein localization [GO:0008104]; protein localization to organelle [GO:0033365] GO:0001917; GO:0003779; GO:0005198; GO:0005200; GO:0005813; GO:0005814; GO:0005829; GO:0005886; GO:0007098; GO:0008104; GO:0010457; GO:0010669; GO:0015629; GO:0019725; GO:0019894; GO:0032053; GO:0033365; GO:0035253; GO:0045494; GO:0045724; GO:0051649; GO:0051656; GO:0097729; GO:0120219; GO:1903566 20642 XM_029336921.2 454 518 374 418 507 NA NA NA NA NA NA 20643 XM_044317821.1 407 0 0 0 0 Q7KTX8 1.89e-67 Mediator of RNA polymerase II transcription subunit 13 (Mediator complex subunit 13) (Mediator complex subunit Skuld) (Protein blind spot) (Protein poils aux pattes) (dTRAP240) Drosophila melanogaster (Fruit fly) cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; compound eye development [GO:0048749]; imaginal disc-derived leg segmentation [GO:0036011]; larval somatic muscle development [GO:0007526]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; regulation of transcription by RNA polymerase II [GO:0006357]; sex comb development [GO:0045498]; transcription initiation at RNA polymerase II promoter [GO:0006367]; wing disc dorsal/ventral pattern formation [GO:0048190] GO:0003712; GO:0005634; GO:0005654; GO:0006357; GO:0006367; GO:0007526; GO:0016592; GO:0022416; GO:0036011; GO:0045165; GO:0045498; GO:0048190; GO:0048749; GO:0070847; GO:0090263 20644 XM_044317821.1 407 0 0 0 0 Q7KTX8 6.27e-46 Mediator of RNA polymerase II transcription subunit 13 (Mediator complex subunit 13) (Mediator complex subunit Skuld) (Protein blind spot) (Protein poils aux pattes) (dTRAP240) Drosophila melanogaster (Fruit fly) cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; compound eye development [GO:0048749]; imaginal disc-derived leg segmentation [GO:0036011]; larval somatic muscle development [GO:0007526]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; regulation of transcription by RNA polymerase II [GO:0006357]; sex comb development [GO:0045498]; transcription initiation at RNA polymerase II promoter [GO:0006367]; wing disc dorsal/ventral pattern formation [GO:0048190] GO:0003712; GO:0005634; GO:0005654; GO:0006357; GO:0006367; GO:0007526; GO:0016592; GO:0022416; GO:0036011; GO:0045165; GO:0045498; GO:0048190; GO:0048749; GO:0070847; GO:0090263 20645 XM_044313006.1 3 24 50 2 7 NA NA NA NA NA NA 20646 XM_029352553.2 818 517 273 620 774 Q8C6G1 2.96e-47 Cilia- and flagella-associated protein 410 Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; cilium assembly [GO:0060271]; cytoskeleton organization [GO:0007010]; regulation of cell shape [GO:0008360]; smoothened signaling pathway [GO:0007224] GO:0001750; GO:0005737; GO:0005739; GO:0005829; GO:0005886; GO:0006974; GO:0007010; GO:0007224; GO:0008360; GO:0032391; GO:0036064; GO:0043231; GO:0060271; GO:0097733 20647 XM_044309673.1 0 32 0 74 0 Q55E58 5.04e-22 Probable serine/threonine-protein kinase pats1 (EC 2.7.11.1) (Protein associated with the transduction of signal 1) Dictyostelium discoideum (Social amoeba) cheating during chimeric sorocarp development [GO:0099139]; mitotic cytokinesis [GO:0000281]; phosphatidylinositol dephosphorylation [GO:0046856]; protein phosphorylation [GO:0006468] GO:0000281; GO:0004438; GO:0004674; GO:0004721; GO:0005524; GO:0005525; GO:0005829; GO:0006468; GO:0042641; GO:0046856; GO:0099139; GO:0106310 20648 XR_003827354.2 609 186 287 349 594 NA NA NA NA NA NA 20649 XM_044329122.1 37 148 20 19 40 NA NA NA NA NA NA 20650 XM_029330094.2 0 0 0 11 7 NA NA NA NA NA NA 20651 XM_029345485.2 85 0 0 0 0 NA NA NA NA NA NA 20652 XM_029344774.2 282 99 92 151 115 NA NA NA NA NA NA 20653 XR_003827894.2 0 0 23 0 0 NA NA NA NA NA NA 20654 XR_003827523.2 27 0 1 13 3 NA NA NA NA NA NA 20655 XM_044327159.1 1224 479 464 460 470 P13676 2.34e-178 Acylamino-acid-releasing enzyme (AARE) (EC 3.4.19.1) (Acyl-peptide hydrolase) (APH) (Acylaminoacyl-peptidase) Rattus norvegicus (Rat) amyloid-beta metabolic process [GO:0050435]; proteolysis [GO:0006508] GO:0004252; GO:0005737; GO:0006508; GO:0008242; GO:0042802; GO:0050435 20656 XM_044320349.1 211 66 71 39 43 NA NA NA NA NA NA 20657 XM_044312936.1 307 0 24 177 0 P43249 0 G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK5) Bos taurus (Bovine) apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell population proliferation [GO:0008284]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell cycle [GO:0051726]; regulation of signal transduction [GO:0009966]; tachykinin receptor signaling pathway [GO:0007217]; Wnt signaling pathway [GO:0016055] GO:0004672; GO:0004674; GO:0004703; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006468; GO:0006915; GO:0007217; GO:0008284; GO:0008289; GO:0009966; GO:0016055; GO:0016607; GO:0031965; GO:0043066; GO:0046777; GO:0047696; GO:0051726 20658 XM_029335921.2 1858 1917 774 1921 2306 P34897 0 Serine hydroxymethyltransferase, mitochondrial (SHMT) (EC 2.1.2.1) (Glycine hydroxymethyltransferase) (Serine methylase) Homo sapiens (Human) folic acid metabolic process [GO:0046655]; glycine biosynthetic process from serine [GO:0019264]; glycine metabolic process [GO:0006544]; L-serine biosynthetic process [GO:0006564]; L-serine catabolic process [GO:0006565]; L-serine metabolic process [GO:0006563]; one-carbon metabolic process [GO:0006730]; positive regulation of cell population proliferation [GO:0008284]; protein homotetramerization [GO:0051289]; protein K63-linked deubiquitination [GO:0070536]; protein tetramerization [GO:0051262]; purine nucleobase biosynthetic process [GO:0009113]; regulation of aerobic respiration [GO:1903715]; regulation of mitochondrial translation [GO:0070129]; regulation of oxidative phosphorylation [GO:0002082]; response to type I interferon [GO:0034340]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653] GO:0000900; GO:0002082; GO:0003682; GO:0004372; GO:0005634; GO:0005737; GO:0005739; GO:0005743; GO:0005758; GO:0005759; GO:0005829; GO:0006544; GO:0006563; GO:0006564; GO:0006565; GO:0006730; GO:0008270; GO:0008284; GO:0008732; GO:0009113; GO:0015630; GO:0019264; GO:0030170; GO:0034340; GO:0035999; GO:0042645; GO:0042803; GO:0046653; GO:0046655; GO:0048027; GO:0051262; GO:0051289; GO:0070062; GO:0070129; GO:0070536; GO:0070552; GO:0070905; GO:1903715 20659 XR_006397154.1 345 582 335 1315 1688 NA NA NA NA NA NA 20660 XM_044320253.1 0 7 0 76 20 NA NA NA NA NA NA 20661 XM_044313434.1 50 8 83 6 179 NA NA NA NA NA NA 20662 XM_029337667.2 974 746 382 793 709 E1C231 0 E3 ubiquitin-protein ligase listerin (EC 2.3.2.27) (RING finger protein 160) (Zfp-294) (RING-type E3 ubiquitin transferase listerin) Gallus gallus (Chicken) rescue of stalled ribosome [GO:0072344]; ribosome-associated ubiquitin-dependent protein catabolic process [GO:1990116] GO:0005829; GO:0008270; GO:0043023; GO:0061630; GO:0072344; GO:1990112; GO:1990116 20663 XR_006391655.1 104 130 162 113 173 NA NA NA NA NA NA 20664 XM_029356418.2 417 294 305 513 556 Q80T69 8.6e-140 Lysine-specific demethylase 9 (KDM9) (EC 1.14.11.-) (Round spermatid basic protein 1) (Rosbin) Mus musculus (Mouse) chromatin organization [GO:0006325] GO:0005634; GO:0006325; GO:0035575; GO:0046872 20665 XM_029334378.2 14 0 27 0 0 B3EWY9 2.77e-41 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 20666 XM_029334378.2 14 0 27 0 0 B3EWY9 9.35e-34 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 20667 XR_006396507.1 51 10 15 48 141 NA NA NA NA NA NA 20668 XM_044308671.1 167 82 113 123 85 E7FAM5 2.35e-53 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 20669 XM_044327329.1 11 2 1 12 24 Q96DM1 2.99e-35 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 20670 XR_006397580.1 145 127 77 22 131 NA NA NA NA NA NA 20671 XM_044320950.1 143 54 109 102 142 NA NA NA NA NA NA 20672 XM_044326148.1 20 0 0 2 32 NA NA NA NA NA NA 20673 XM_029342915.2 0 0 0 114 232 P82094 1.01e-119 TATA element modulatory factor (TMF) (Androgen receptor coactivator 160 kDa protein) (Androgen receptor-associated protein of 160 kDa) Homo sapiens (Human) acrosome assembly [GO:0001675]; androgen receptor signaling pathway [GO:0030521]; defense response to bacterium [GO:0042742]; epithelial cell apoptotic process [GO:1904019]; flagellated sperm motility [GO:0030317]; Leydig cell differentiation [GO:0033327]; luteinizing hormone secretion [GO:0032275]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of gene expression [GO:0010629]; positive regulation of cytokine production [GO:0001819]; positive regulation of testosterone secretion [GO:2000845]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of proteasomal protein catabolic process [GO:0061136]; spermatid nucleus differentiation [GO:0007289] GO:0000139; GO:0001675; GO:0001819; GO:0003677; GO:0005634; GO:0005783; GO:0005794; GO:0005829; GO:0007289; GO:0010629; GO:0030317; GO:0030374; GO:0030521; GO:0032275; GO:0033327; GO:0042742; GO:0045944; GO:0050681; GO:0061136; GO:1904019; GO:1904036; GO:2000845 20674 XM_044319214.1 164 109 11 84 154 NA NA NA NA NA NA 20675 XM_044309409.1 941 646 270225 851 379 NA NA NA NA NA NA 20676 XM_044316440.1 12 0 2 11 7 NA NA NA NA NA NA 20677 XM_029335242.2 1661 1010 822 1245 1161 P28749 0 Retinoblastoma-like protein 1 (107 kDa retinoblastoma-associated protein) (p107) (pRb1) Homo sapiens (Human) cell cycle [GO:0007049]; cell differentiation [GO:0030154]; chromatin organization [GO:0006325]; negative regulation of cellular senescence [GO:2000773]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of lipid kinase activity [GO:0043550] GO:0000122; GO:0000785; GO:0000977; GO:0005654; GO:0005667; GO:0006325; GO:0007049; GO:0010629; GO:0030154; GO:0043550; GO:1990841; GO:2000134; GO:2000773 20678 XM_029338070.2 146 209 87 172 141 NA NA NA NA NA NA 20679 XM_044329175.1 0 249 0 46 329 Q9P1Y6 1.22e-37 PHD and RING finger domain-containing protein 1 Homo sapiens (Human) mRNA processing [GO:0006397]; transcription by RNA polymerase II [GO:0006366] GO:0006366; GO:0006397; GO:0016020; GO:0019904; GO:0046872; GO:0070063 20680 XM_029338428.2 1673 724 610 1011 1315 Q3KP44 1.18e-24 Ankyrin repeat domain-containing protein 55 Homo sapiens (Human) NA NA 20681 XR_003828199.2 5 8 4 7 22 NA NA NA NA NA NA 20682 XM_044309112.1 217 0 375 556 584 NA NA NA NA NA NA 20683 XM_044328135.1 434 267 293 827 306 Q5RF65 3.42e-147 Cytosolic beta-glucosidase (EC 3.2.1.21) (Cytosolic galactosylceramidase) (EC 3.2.1.46) (Cytosolic glucosylceramidase) (EC 3.2.1.45) (Cytosolic glycosylceramidase) (Cytosolic GCase) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) beta-glucoside catabolic process [GO:1901805]; carbohydrate metabolic process [GO:0005975]; galactosylceramide catabolic process [GO:0006683]; glucosylceramide catabolic process [GO:0006680] GO:0004336; GO:0004348; GO:0004565; GO:0005829; GO:0005975; GO:0006680; GO:0006683; GO:0008422; GO:0017042; GO:0102483; GO:1901805 20684 XM_029357161.2 127 0 0 200 63 NA NA NA NA NA NA 20685 XM_044314399.1 36 1 4 38 14 NA NA NA NA NA NA 20686 XM_029348344.2 784 446 501 711 734 Q5ZLL7 1.98e-105 WD repeat-containing protein 91 Gallus gallus (Chicken) early endosome to late endosome transport [GO:0045022]; regulation of phosphatidylinositol 3-kinase activity [GO:0043551] GO:0005829; GO:0031313; GO:0031901; GO:0031902; GO:0035014; GO:0043551; GO:0045022 20687 XM_029348344.2 784 446 501 711 734 Q5ZLL7 1.47e-56 WD repeat-containing protein 91 Gallus gallus (Chicken) early endosome to late endosome transport [GO:0045022]; regulation of phosphatidylinositol 3-kinase activity [GO:0043551] GO:0005829; GO:0031313; GO:0031901; GO:0031902; GO:0035014; GO:0043551; GO:0045022 20688 XM_044320890.1 42 47 13 2 196 Q94K49 5.68e-25 Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1 (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) epigenetic regulation of gene expression [GO:0040029] GO:0003682; GO:0004518; GO:0005634; GO:0035098; GO:0035102; GO:0040029; GO:0046872 20689 XR_003823330.2 194 215 54 48 64 NA NA NA NA NA NA 20690 XM_029329772.2 0 4 16 10 56 NA NA NA NA NA NA 20691 XM_044310758.1 28 1 34 4 202 NA NA NA NA NA NA 20692 XR_006395190.1 143 44 159 67 246 NA NA NA NA NA NA 20693 XM_029357730.2 150 37 0 111 30 Q6ZXV5 3.72e-102 Protein O-mannosyl-transferase TMTC3 (EC 2.4.1.109) (Protein SMILE) (Transmembrane and TPR repeat-containing protein 3) Homo sapiens (Human) positive regulation of proteasomal protein catabolic process [GO:1901800]; protein O-linked mannosylation [GO:0035269]; response to endoplasmic reticulum stress [GO:0034976] GO:0000030; GO:0004169; GO:0005783; GO:0016020; GO:0034976; GO:0035269; GO:1901800 20694 XM_044320516.1 36 45 0 0 0 NA NA NA NA NA NA 20695 XM_029357215.2 4116 3829 3789 5652 4242 O55164 4.4e-131 Multiple PDZ domain protein (Multi-PDZ domain protein 1) Rattus norvegicus (Rat) cell adhesion [GO:0007155]; dendrite development [GO:0016358]; intracellular protein transport [GO:0006886]; intracellular signal transduction [GO:0035556]; myelination [GO:0042552] GO:0005737; GO:0005923; GO:0006886; GO:0007155; GO:0008022; GO:0012505; GO:0014069; GO:0016324; GO:0016327; GO:0016358; GO:0030425; GO:0031410; GO:0035003; GO:0035556; GO:0042552; GO:0043220; GO:0045202; GO:0098978 20696 XM_029357215.2 4116 3829 3789 5652 4242 O55164 8.51e-131 Multiple PDZ domain protein (Multi-PDZ domain protein 1) Rattus norvegicus (Rat) cell adhesion [GO:0007155]; dendrite development [GO:0016358]; intracellular protein transport [GO:0006886]; intracellular signal transduction [GO:0035556]; myelination [GO:0042552] GO:0005737; GO:0005923; GO:0006886; GO:0007155; GO:0008022; GO:0012505; GO:0014069; GO:0016324; GO:0016327; GO:0016358; GO:0030425; GO:0031410; GO:0035003; GO:0035556; GO:0042552; GO:0043220; GO:0045202; GO:0098978 20697 XM_029357215.2 4116 3829 3789 5652 4242 O55164 1.03e-39 Multiple PDZ domain protein (Multi-PDZ domain protein 1) Rattus norvegicus (Rat) cell adhesion [GO:0007155]; dendrite development [GO:0016358]; intracellular protein transport [GO:0006886]; intracellular signal transduction [GO:0035556]; myelination [GO:0042552] GO:0005737; GO:0005923; GO:0006886; GO:0007155; GO:0008022; GO:0012505; GO:0014069; GO:0016324; GO:0016327; GO:0016358; GO:0030425; GO:0031410; GO:0035003; GO:0035556; GO:0042552; GO:0043220; GO:0045202; GO:0098978 20698 XM_029357215.2 4116 3829 3789 5652 4242 O55164 5.43e-22 Multiple PDZ domain protein (Multi-PDZ domain protein 1) Rattus norvegicus (Rat) cell adhesion [GO:0007155]; dendrite development [GO:0016358]; intracellular protein transport [GO:0006886]; intracellular signal transduction [GO:0035556]; myelination [GO:0042552] GO:0005737; GO:0005923; GO:0006886; GO:0007155; GO:0008022; GO:0012505; GO:0014069; GO:0016324; GO:0016327; GO:0016358; GO:0030425; GO:0031410; GO:0035003; GO:0035556; GO:0042552; GO:0043220; GO:0045202; GO:0098978 20699 XM_044323018.1 0 1072 31 2345 0 P02466 4.98e-46 Collagen alpha-2(I) chain (Alpha-2 type I collagen) Rattus norvegicus (Rat) blood vessel development [GO:0001568]; bone mineralization [GO:0030282]; cellular response to amino acid stimulus [GO:0071230]; cellular response to organic substance [GO:0071310]; cellular response to retinoic acid [GO:0071300]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; extracellular matrix assembly [GO:0085029]; extracellular matrix organization [GO:0030198]; protein heterotrimerization [GO:0070208]; regulation of blood pressure [GO:0008217]; response to norepinephrine [GO:0071873]; Rho protein signal transduction [GO:0007266]; skeletal system development [GO:0001501]; skin morphogenesis [GO:0043589]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001501; GO:0001568; GO:0002020; GO:0005201; GO:0005576; GO:0005581; GO:0005584; GO:0005615; GO:0007179; GO:0007266; GO:0008217; GO:0030198; GO:0030199; GO:0030282; GO:0030674; GO:0031012; GO:0032963; GO:0042802; GO:0043589; GO:0046332; GO:0046872; GO:0048407; GO:0062023; GO:0070208; GO:0071230; GO:0071300; GO:0071310; GO:0071873; GO:0085029; GO:0097067 20700 XM_029340671.2 999 730 485 849 851 NA NA NA NA NA NA 20701 XM_029347254.2 395 236 208 320 293 NA NA NA NA NA NA 20702 XM_029358466.2 1059 713 684 681 706 Q5FVB0 3.06e-38 Ataxin-10 (Spinocerebellar ataxia type 10 protein homolog) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0048471 20703 XM_044320479.1 30 9 65 12 57 NA NA NA NA NA NA 20704 XM_044323985.1 1 269 0 0 2 NA NA NA NA NA NA 20705 XM_029341850.2 250 207 95 222 262 NA NA NA NA NA NA 20706 XM_044306844.1 939 610 860 960 890 NA NA NA NA NA NA 20707 XM_029334087.2 830 375 331 322 323 NA NA NA NA NA NA 20708 XM_044328936.1 2564 4861 622 8985 14810 P63018 0 Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) Rattus norvegicus (Rat) aging [GO:0007568]; ATP metabolic process [GO:0046034]; axo-dendritic transport [GO:0008088]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; cerebellum development [GO:0021549]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein folding [GO:0061077]; clathrin coat disassembly [GO:0072318]; estrous cycle [GO:0044849]; forebrain development [GO:0030900]; G1/S transition of mitotic cell cycle [GO:0000082]; kidney development [GO:0001822]; late endosomal microautophagy [GO:0061738]; maintenance of postsynaptic specialization structure [GO:0098880]; modulation by host of viral process [GO:0044788]; mRNA processing [GO:0006397]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of supramolecular fiber organization [GO:1902904]; positive regulation by host of viral genome replication [GO:0044829]; positive regulation of catalytic activity [GO:0043085]; positive regulation of gene expression [GO:0010628]; positive regulation of lysosomal membrane permeability [GO:0097214]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein refolding [GO:1904592]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein autophosphorylation [GO:0046777]; protein folding [GO:0006457]; protein import into nucleus [GO:0006606]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; protein transmembrane import into intracellular organelle [GO:0044743]; protein-containing complex disassembly [GO:0032984]; regulation of cell cycle [GO:0051726]; regulation of postsynapse organization [GO:0099175]; regulation of protein complex stability [GO:0061635]; regulation of protein stability [GO:0031647]; response to activity [GO:0014823]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to nickel cation [GO:0010045]; response to odorant [GO:1990834]; response to progesterone [GO:0032570]; response to starvation [GO:0042594]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; sensory perception of smell [GO:0007608]; skeletal muscle tissue development [GO:0007519]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192] GO:0000082; GO:0000974; GO:0001664; GO:0001786; GO:0001822; GO:0001916; GO:0001917; GO:0003723; GO:0005102; GO:0005524; GO:0005634; GO:0005681; GO:0005730; GO:0005737; GO:0005764; GO:0005765; GO:0005770; GO:0005776; GO:0005829; GO:0005874; GO:0005882; GO:0005886; GO:0006397; GO:0006457; GO:0006606; GO:0007519; GO:0007568; GO:0007608; GO:0008021; GO:0008088; GO:0008380; GO:0009408; GO:0009410; GO:0009986; GO:0010045; GO:0010628; GO:0010667; GO:0014069; GO:0014823; GO:0016191; GO:0016192; GO:0016887; GO:0019899; GO:0021549; GO:0030424; GO:0030425; GO:0030674; GO:0030900; GO:0031072; GO:0031625; GO:0031647; GO:0031686; GO:0032279; GO:0032355; GO:0032570; GO:0032984; GO:0032991; GO:0034605; GO:0034620; GO:0042026; GO:0042277; GO:0042470; GO:0042594; GO:0043005; GO:0043025; GO:0043085; GO:0043195; GO:0043197; GO:0043198; GO:0043202; GO:0043204; GO:0043531; GO:0044183; GO:0044309; GO:0044743; GO:0044788; GO:0044829; GO:0044849; GO:0045121; GO:0045471; GO:0045862; GO:0045892; GO:0046034; GO:0046777; GO:0048026; GO:0048471; GO:0050766; GO:0051082; GO:0051085; GO:0051087; GO:0051726; GO:0051787; GO:0055131; GO:0061077; GO:0061635; GO:0061684; GO:0061738; GO:0061740; GO:0070062; GO:0071276; GO:0072318; GO:0097214; GO:0098684; GO:0098690; GO:0098793; GO:0098794; GO:0098880; GO:0098978; GO:0099175; GO:0099523; GO:0099524; GO:0099634; GO:0101031; GO:0140545; GO:0140662; GO:1902904; GO:1903206; GO:1904592; GO:1904593; GO:1904764; GO:1990124; GO:1990832; GO:1990833; GO:1990834; GO:1990836; GO:1990904 20709 XM_029341859.2 0 34 0 0 0 NA NA NA NA NA NA 20710 XM_044316476.1 52 15 73 57 205 NA NA NA NA NA NA 20711 XM_029328395.2 6484 5642 1150 2275 1735 O97125 0 Heat shock protein 68 Drosophila melanogaster (Fruit fly) cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; determination of adult lifespan [GO:0008340]; protein refolding [GO:0042026]; response to starvation [GO:0042594]; vesicle-mediated transport [GO:0016192] GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0008340; GO:0016192; GO:0016887; GO:0031072; GO:0034620; GO:0042026; GO:0042594; GO:0044183; GO:0051082; GO:0051085; GO:0051787; GO:0140662 20712 XM_044313713.1 27 0 0 5 10 NA NA NA NA NA NA 20713 XM_044307321.1 1060 1772 1008 1216 851 NA NA NA NA NA NA 20714 XR_006398105.1 397 137 180 152 437 NA NA NA NA NA NA 20715 XM_044327187.1 15 1 18 121 76 NA NA NA NA NA NA 20716 XM_029357840.2 49 75 53 121 13 Q5XXP2 3.86e-28 Melanopsin (Opsin-4) Phodopus sungorus (Striped hairy-footed hamster) (Djungarian hamster) hyaloid vascular plexus regression [GO:1990384]; optokinetic behavior [GO:0007634]; phototransduction [GO:0007602]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511]; visual perception [GO:0007601] GO:0005502; GO:0005886; GO:0007601; GO:0007602; GO:0007634; GO:0008020; GO:0016020; GO:0030424; GO:0030425; GO:0042752; GO:0043204; GO:0048511; GO:1990384 20717 XM_044321345.1 12 16 0 0 0 P46023 2.2e-93 G-protein coupled receptor GRL101 Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004930; GO:0005886 20718 XM_029348052.2 571 182 180 262 457 NA NA NA NA NA NA 20719 XM_044308639.1 0 0 0 6 6 D3YXG0 4.03e-66 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 20720 XM_044308639.1 0 0 0 6 6 D3YXG0 2.06e-51 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 20721 XM_044308639.1 0 0 0 6 6 D3YXG0 2.7e-47 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 20722 XM_044308639.1 0 0 0 6 6 D3YXG0 1.58e-40 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 20723 XM_044308639.1 0 0 0 6 6 D3YXG0 1.7e-40 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 20724 XM_044308639.1 0 0 0 6 6 D3YXG0 1.96e-40 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 20725 XM_044308639.1 0 0 0 6 6 D3YXG0 3.47e-40 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 20726 XM_044308639.1 0 0 0 6 6 D3YXG0 4.86e-40 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 20727 XM_044308639.1 0 0 0 6 6 D3YXG0 2.56e-39 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 20728 XM_044308639.1 0 0 0 6 6 D3YXG0 4.97e-39 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 20729 XM_044308639.1 0 0 0 6 6 D3YXG0 1.14e-36 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 20730 XM_044308639.1 0 0 0 6 6 D3YXG0 1.58e-36 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 20731 XM_044308639.1 0 0 0 6 6 D3YXG0 1.4e-33 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 20732 XR_006397726.1 195 105 184 198 73 NA NA NA NA NA NA 20733 XM_029338113.2 9 19 14 9 23 NA NA NA NA NA NA 20734 XM_029334532.2 321 266 259 282 350 Q91029 1.56e-106 Protein Wnt-1 Gallus gallus (Chicken) apoptotic process [GO:0006915]; BMP signaling pathway [GO:0030509]; canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; determination of dorsal identity [GO:0048263]; dorsal/ventral pattern formation [GO:0009953]; neuron differentiation [GO:0030182]; positive regulation of protein-containing complex assembly [GO:0031334] GO:0005109; GO:0005125; GO:0005615; GO:0006915; GO:0009953; GO:0030182; GO:0030509; GO:0031334; GO:0045165; GO:0048263; GO:0060070 20735 XM_029345925.2 11385 5762 4434 6004 6365 Q9WV92 4.17e-104 Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1) (Erythrocyte membrane protein band 4.1-like 3) [Cleaved into: Band 4.1-like protein 3, N-terminally processed] Mus musculus (Mouse) actomyosin structure organization [GO:0031032]; apoptotic process [GO:0006915]; axon development [GO:0061564]; cortical actin cytoskeleton organization [GO:0030866]; cortical cytoskeleton organization [GO:0030865]; myelin maintenance [GO:0043217]; neuron projection morphogenesis [GO:0048812]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; protein localization to plasma membrane [GO:0072659]; regulation of cell shape [GO:0008360] GO:0002175; GO:0003779; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0005911; GO:0006915; GO:0008360; GO:0014069; GO:0030054; GO:0030865; GO:0030866; GO:0030913; GO:0031032; GO:0033270; GO:0043217; GO:0044224; GO:0048812; GO:0061564; GO:0071205; GO:0072659; GO:0106006; GO:1990227 20736 XM_029338126.1 540 550 227 285 388 Q9CQL5 6.79e-26 39S ribosomal protein L18, mitochondrial (L18mt) (MRP-L18) Mus musculus (Mouse) mitochondrial translation [GO:0032543]; rRNA import into mitochondrion [GO:0035928] GO:0003735; GO:0005739; GO:0005743; GO:0005762; GO:0008097; GO:0032543; GO:0035928 20737 XR_006396406.1 1131 936 364 1184 915 NA NA NA NA NA NA 20738 XR_006392560.1 75 39 54 36 99 NA NA NA NA NA NA 20739 XM_044321498.1 0 0 44 0 0 NA NA NA NA NA NA 20740 XM_029332543.2 637 213 421 604 289 NA NA NA NA NA NA 20741 XM_044311099.1 72 16 40 131 59 NA NA NA NA NA NA 20742 XM_029344036.2 90 64 49 48 63 NA NA NA NA NA NA 20743 XR_003827879.2 45 16 18 31 61 NA NA NA NA NA NA 20744 XM_029346762.2 174 49 159 71 46 NA NA NA NA NA NA 20745 XR_003825066.2 146 15 52 78 138 NA NA NA NA NA NA 20746 XM_044312504.1 38 21 19 25 117 P84239 3.62e-84 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 20747 XM_044312504.1 38 21 19 25 117 P84239 3.62e-84 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 20748 XM_044324102.1 0 0 5 0 6 NA NA NA NA NA NA 20749 XM_044327371.1 8 0 0 2 1 NA NA NA NA NA NA 20750 XR_006396086.1 248 111 274 31 211 NA NA NA NA NA NA 20751 XM_029326993.2 0 15 15 101 84 Q8BYI6 1.27e-142 Lysophosphatidylcholine acyltransferase 2 (LPC acyltransferase 2) (LPCAT-2) (LysoPC acyltransferase 2) (EC 2.3.1.23) (1-acylglycerol-3-phosphate O-acyltransferase 11) (1-AGP acyltransferase 11) (1-AGPAT 11) (EC 2.3.1.51) (1-acylglycerophosphocholine O-acyltransferase) (1-alkenylglycerophosphocholine O-acyltransferase) (EC 2.3.1.25) (1-alkylglycerophosphocholine O-acetyltransferase) (EC 2.3.1.67) (Acetyl-CoA:lyso-platelet-activating factor acetyltransferase) (Acetyl-CoA:lyso-PAF acetyltransferase) (Lyso-PAF acetyltransferase) (LysoPAFAT) (Acyltransferase-like 1) Mus musculus (Mouse) membrane organization [GO:0061024]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; platelet activating factor biosynthetic process [GO:0006663] GO:0000139; GO:0003841; GO:0005509; GO:0005783; GO:0005789; GO:0005795; GO:0005811; GO:0005886; GO:0006663; GO:0016020; GO:0036151; GO:0047159; GO:0047184; GO:0047192; GO:0050200; GO:0061024 20752 XR_006394773.1 1 0 2 3 7 NA NA NA NA NA NA 20753 XM_029336162.2 32 26 1 18 10 NA NA NA NA NA NA 20754 XM_044319575.1 162 124 157 95 523 NA NA NA NA NA NA 20755 XR_006396321.1 3 0 0 13 10 NA NA NA NA NA NA 20756 XM_029337663.2 882 721 544 789 953 Q5JWR5 0 Protein dopey-1 Homo sapiens (Human) Golgi to endosome transport [GO:0006895]; protein transport [GO:0015031] GO:0000139; GO:0005768; GO:0005802; GO:0005829; GO:0006895; GO:0015031 20757 XM_029337663.2 882 721 544 789 953 Q5JWR5 2.96e-131 Protein dopey-1 Homo sapiens (Human) Golgi to endosome transport [GO:0006895]; protein transport [GO:0015031] GO:0000139; GO:0005768; GO:0005802; GO:0005829; GO:0006895; GO:0015031 20758 XM_029337663.2 882 721 544 789 953 Q5JWR5 4.01e-41 Protein dopey-1 Homo sapiens (Human) Golgi to endosome transport [GO:0006895]; protein transport [GO:0015031] GO:0000139; GO:0005768; GO:0005802; GO:0005829; GO:0006895; GO:0015031 20759 XM_044315711.1 0 55 0 0 0 NA NA NA NA NA NA 20760 XM_044314257.1 1809 1233 1403 1080 1106 Q5RD27 1.04e-87 SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) (Serine/arginine-rich protein-specific kinase 1) (SR-protein-specific kinase 1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cell differentiation [GO:0030154]; chromosome segregation [GO:0007059]; intracellular signal transduction [GO:0035556]; mRNA processing [GO:0006397]; protein phosphorylation [GO:0006468]; regulation of mRNA processing [GO:0050684]; RNA splicing [GO:0008380] GO:0000287; GO:0000785; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005783; GO:0006397; GO:0006468; GO:0007059; GO:0008380; GO:0016363; GO:0016607; GO:0030154; GO:0035556; GO:0050684; GO:0106310 20761 XM_044314257.1 1809 1233 1403 1080 1106 Q5RD27 3.61e-81 SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) (Serine/arginine-rich protein-specific kinase 1) (SR-protein-specific kinase 1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cell differentiation [GO:0030154]; chromosome segregation [GO:0007059]; intracellular signal transduction [GO:0035556]; mRNA processing [GO:0006397]; protein phosphorylation [GO:0006468]; regulation of mRNA processing [GO:0050684]; RNA splicing [GO:0008380] GO:0000287; GO:0000785; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005783; GO:0006397; GO:0006468; GO:0007059; GO:0008380; GO:0016363; GO:0016607; GO:0030154; GO:0035556; GO:0050684; GO:0106310 20762 XM_029354094.2 0 0 0 7 0 NA NA NA NA NA NA 20763 XR_006395404.1 25 19 8 20 6 NA NA NA NA NA NA 20764 XM_044318693.1 103 5 51 444 185 Q7Z494 3.64e-43 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 20765 XM_044318693.1 103 5 51 444 185 Q7Z494 2.84e-42 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 20766 XM_044318693.1 103 5 51 444 185 Q7Z494 2.83e-36 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 20767 XM_044318693.1 103 5 51 444 185 Q7Z494 7.73e-29 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 20768 XM_044318693.1 103 5 51 444 185 Q7Z494 8.93e-26 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 20769 XM_044318693.1 103 5 51 444 185 Q7Z494 1.16e-25 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 20770 XM_044318693.1 103 5 51 444 185 Q7Z494 7.95e-24 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 20771 XR_006397210.1 19 14 46 2 124 NA NA NA NA NA NA 20772 XM_044326695.1 25 41 54 15 8 NA NA NA NA NA NA 20773 XM_029333882.2 9474 10702 6553 9488 7150 Q60631 1.51e-76 Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) Mus musculus (Mouse) actin cytoskeleton reorganization [GO:0031532]; aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; B cell receptor signaling pathway [GO:0050853]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cellular response to ionizing radiation [GO:0071479]; endodermal cell differentiation [GO:0035987]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction [GO:0007165]; signal transduction in response to DNA damage [GO:0042770] GO:0001784; GO:0005068; GO:0005091; GO:0005154; GO:0005168; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005768; GO:0005794; GO:0005829; GO:0005886; GO:0005911; GO:0007165; GO:0007173; GO:0007265; GO:0007568; GO:0008180; GO:0008286; GO:0008543; GO:0012506; GO:0016020; GO:0017124; GO:0019899; GO:0019901; GO:0019903; GO:0019904; GO:0030674; GO:0030838; GO:0031532; GO:0031623; GO:0032991; GO:0035987; GO:0042770; GO:0042802; GO:0043408; GO:0043539; GO:0043560; GO:0044877; GO:0046875; GO:0048009; GO:0048646; GO:0050853; GO:0051219; GO:0060670; GO:0070436; GO:0071479; GO:0140677; GO:2000379 20774 XR_006398185.1 20 12 26 16 50 NA NA NA NA NA NA 20775 XM_044312793.1 0 163 9 0 152 P45954 0 Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial (SBCAD) (EC 1.3.8.5) (2-methyl branched chain acyl-CoA dehydrogenase) (2-MEBCAD) (2-methylbutyryl-coenzyme A dehydrogenase) (2-methylbutyryl-CoA dehydrogenase) Homo sapiens (Human) fatty acid metabolic process [GO:0006631]; isoleucine catabolic process [GO:0006550] GO:0003853; GO:0003995; GO:0005739; GO:0005759; GO:0006550; GO:0006631; GO:0016937; GO:0042802; GO:0050660; GO:0102035 20776 XM_029327391.2 638 373 366 566 739 B0DOB4 0 Nephrocystin-4 Xenopus laevis (African clawed frog) negative regulation of canonical Wnt signaling pathway [GO:0090090] GO:0005737; GO:0005856; GO:0090090; GO:0097730 20777 XM_044326829.1 35 0 0 19 42 NA NA NA NA NA NA 20778 XM_044328560.1 1418 831 689 1378 1654 P42620 5.55e-120 Glutathionyl-hydroquinone reductase YqjG (GS-HQR) (EC 1.8.5.7) Escherichia coli (strain K12) NA GO:0004364; GO:0005737; GO:0016672 20779 XM_029329316.2 46 19 47 251 68 NA NA NA NA NA NA 20780 XM_044315550.1 2 0 13 9 4 NA NA NA NA NA NA 20781 XM_029330648.2 0 81 42 122 54 Q32KH5 0 N-acetylgalactosamine-6-sulfatase (EC 3.1.6.4) (Chondroitinsulfatase) (Chondroitinase) (Galactose-6-sulfate sulfatase) (N-acetylgalactosamine-6-sulfate sulfatase) (GalNAc6S sulfatase) Canis lupus familiaris (Dog) (Canis familiaris) NA GO:0004065; GO:0005764; GO:0043890; GO:0046872 20782 XM_029337611.2 10 1 0 6 14 NA NA NA NA NA NA 20783 XM_044309899.1 9 3 5 28 56 NA NA NA NA NA NA 20784 XR_003828259.2 3123 2832 1964 1866 1913 NA NA NA NA NA NA 20785 XM_044319041.1 27 205 137 286 41 NA NA NA NA NA NA 20786 XM_044309817.1 3 0 0 6 0 NA NA NA NA NA NA 20787 XM_029327964.2 396 301 200 594 422 Q8WUA2 6.28e-159 Peptidyl-prolyl cis-trans isomerase-like 4 (PPIase) (EC 5.2.1.8) (Cyclophilin-like protein PPIL4) (Rotamase PPIL4) Homo sapiens (Human) protein peptidyl-prolyl isomerization [GO:0000413]; regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901407] GO:0000413; GO:0003723; GO:0003755; GO:0005634; GO:0005654; GO:0005829; GO:1901407 20788 XM_044310008.1 115 42 30 66 129 NA NA NA NA NA NA 20789 XM_044319723.1 125 226 229 199 122 Q9VS29 5.82e-27 Cell adhesion molecule Dscam2 (Down syndrome cell adhesion molecule-like protein Dscam2) Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; dendrite self-avoidance [GO:0070593]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron projection morphogenesis [GO:0048812] GO:0005886; GO:0007156; GO:0007411; GO:0030424; GO:0042802; GO:0048812; GO:0070593; GO:0098632 20790 XM_044319723.1 125 226 229 199 122 Q9VS29 2.27e-22 Cell adhesion molecule Dscam2 (Down syndrome cell adhesion molecule-like protein Dscam2) Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; dendrite self-avoidance [GO:0070593]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron projection morphogenesis [GO:0048812] GO:0005886; GO:0007156; GO:0007411; GO:0030424; GO:0042802; GO:0048812; GO:0070593; GO:0098632 20791 XM_029333435.2 1604 497 329 914 940 P55115 1.03e-47 Zinc metalloproteinase nas-15 (EC 3.4.24.-) (Nematode astacin 15) Caenorhabditis elegans proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0006508; GO:0008270 20792 XM_044319451.1 2952 1628 3408 8165 9731 A6NMZ7 6.6e-82 Collagen alpha-6(VI) chain Homo sapiens (Human) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 20793 XM_044319451.1 2952 1628 3408 8165 9731 A6NMZ7 3.13e-56 Collagen alpha-6(VI) chain Homo sapiens (Human) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 20794 XM_044319451.1 2952 1628 3408 8165 9731 A6NMZ7 7.91e-54 Collagen alpha-6(VI) chain Homo sapiens (Human) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 20795 XM_044319451.1 2952 1628 3408 8165 9731 A6NMZ7 2.18e-53 Collagen alpha-6(VI) chain Homo sapiens (Human) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 20796 XM_044319451.1 2952 1628 3408 8165 9731 A6NMZ7 1.75e-52 Collagen alpha-6(VI) chain Homo sapiens (Human) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 20797 XM_044319451.1 2952 1628 3408 8165 9731 A6NMZ7 4.48e-52 Collagen alpha-6(VI) chain Homo sapiens (Human) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 20798 XM_044319451.1 2952 1628 3408 8165 9731 A6NMZ7 6.22e-52 Collagen alpha-6(VI) chain Homo sapiens (Human) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 20799 XM_044319451.1 2952 1628 3408 8165 9731 A6NMZ7 1.04e-51 Collagen alpha-6(VI) chain Homo sapiens (Human) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 20800 XM_044319451.1 2952 1628 3408 8165 9731 A6NMZ7 3.31e-51 Collagen alpha-6(VI) chain Homo sapiens (Human) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 20801 XM_044319451.1 2952 1628 3408 8165 9731 A6NMZ7 7.28e-51 Collagen alpha-6(VI) chain Homo sapiens (Human) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 20802 XM_044319451.1 2952 1628 3408 8165 9731 A6NMZ7 7.36e-49 Collagen alpha-6(VI) chain Homo sapiens (Human) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 20803 XM_044319451.1 2952 1628 3408 8165 9731 A6NMZ7 4.77e-45 Collagen alpha-6(VI) chain Homo sapiens (Human) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 20804 XM_044319451.1 2952 1628 3408 8165 9731 A6NMZ7 3.1e-44 Collagen alpha-6(VI) chain Homo sapiens (Human) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 20805 XM_044319451.1 2952 1628 3408 8165 9731 A6NMZ7 1.73e-43 Collagen alpha-6(VI) chain Homo sapiens (Human) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 20806 XM_044319451.1 2952 1628 3408 8165 9731 A6NMZ7 2.57e-43 Collagen alpha-6(VI) chain Homo sapiens (Human) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 20807 XM_044319451.1 2952 1628 3408 8165 9731 A6NMZ7 1e-42 Collagen alpha-6(VI) chain Homo sapiens (Human) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 20808 XM_044319451.1 2952 1628 3408 8165 9731 A6NMZ7 7.68e-42 Collagen alpha-6(VI) chain Homo sapiens (Human) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 20809 XM_044319451.1 2952 1628 3408 8165 9731 A6NMZ7 1.85e-33 Collagen alpha-6(VI) chain Homo sapiens (Human) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 20810 XM_044319451.1 2952 1628 3408 8165 9731 A6NMZ7 4.72e-31 Collagen alpha-6(VI) chain Homo sapiens (Human) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 20811 XM_044319451.1 2952 1628 3408 8165 9731 A6NMZ7 5.35e-31 Collagen alpha-6(VI) chain Homo sapiens (Human) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 20812 XM_044319451.1 2952 1628 3408 8165 9731 A6NMZ7 8.14e-31 Collagen alpha-6(VI) chain Homo sapiens (Human) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 20813 XM_044319451.1 2952 1628 3408 8165 9731 A6NMZ7 3.17e-30 Collagen alpha-6(VI) chain Homo sapiens (Human) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 20814 XM_044319451.1 2952 1628 3408 8165 9731 A6NMZ7 6.26e-29 Collagen alpha-6(VI) chain Homo sapiens (Human) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 20815 XM_044319451.1 2952 1628 3408 8165 9731 A6NMZ7 9.05e-29 Collagen alpha-6(VI) chain Homo sapiens (Human) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 20816 XM_044319451.1 2952 1628 3408 8165 9731 A6NMZ7 2.11e-28 Collagen alpha-6(VI) chain Homo sapiens (Human) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 20817 XM_044319451.1 2952 1628 3408 8165 9731 A6NMZ7 4.27e-28 Collagen alpha-6(VI) chain Homo sapiens (Human) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 20818 XM_044319451.1 2952 1628 3408 8165 9731 A6NMZ7 7.68e-25 Collagen alpha-6(VI) chain Homo sapiens (Human) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 20819 XM_044319451.1 2952 1628 3408 8165 9731 A6NMZ7 8.78e-25 Collagen alpha-6(VI) chain Homo sapiens (Human) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 20820 XM_044319451.1 2952 1628 3408 8165 9731 A6NMZ7 2.61e-24 Collagen alpha-6(VI) chain Homo sapiens (Human) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 20821 XM_044319451.1 2952 1628 3408 8165 9731 A6NMZ7 8.03e-24 Collagen alpha-6(VI) chain Homo sapiens (Human) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 20822 XM_029333937.2 1687 1038 876 2178 1379 NA NA NA NA NA NA 20823 XM_029334115.2 0 0 0 0 39 Q60547 9.41e-34 Synaptonemal complex protein 3 (SCP-3) (Meiotic chromosome core protein) (Synaptonemal complex protein COR1) Mesocricetus auratus (Golden hamster) cell division [GO:0051301]; meiotic cell cycle [GO:0051321] GO:0000775; GO:0000800; GO:0003677; GO:0005694; GO:0051301; GO:0051321 20824 XM_029334933.2 98 10 0 264 333 NA NA NA NA NA NA 20825 XM_029338147.2 443 115 478 240 0 Q8CBF3 0 Ephrin type-B receptor 1 (EC 2.7.10.1) Mus musculus (Mouse) angiogenesis [GO:0001525]; axon guidance [GO:0007411]; camera-type eye morphogenesis [GO:0048593]; cell chemotaxis [GO:0060326]; cell-substrate adhesion [GO:0031589]; central nervous system projection neuron axonogenesis [GO:0021952]; cranial nerve development [GO:0021545]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; ephrin receptor signaling pathway [GO:0048013]; establishment of cell polarity [GO:0030010]; hindbrain tangential cell migration [GO:0021934]; immunological synapse formation [GO:0001771]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of satellite cell differentiation [GO:1902725]; negative regulation of skeletal muscle satellite cell proliferation [GO:1902723]; neural precursor cell proliferation [GO:0061351]; neurogenesis [GO:0022008]; optic nerve morphogenesis [GO:0021631]; positive regulation of kinase activity [GO:0033674]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of neuron death [GO:1901214]; retinal ganglion cell axon guidance [GO:0031290]; skeletal muscle satellite cell activation [GO:0014719]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0001525; GO:0001771; GO:0004713; GO:0004714; GO:0005005; GO:0005524; GO:0005737; GO:0005783; GO:0005829; GO:0005886; GO:0007169; GO:0007411; GO:0008046; GO:0014719; GO:0016020; GO:0021545; GO:0021631; GO:0021934; GO:0021952; GO:0022008; GO:0030010; GO:0030424; GO:0030425; GO:0031290; GO:0031589; GO:0031901; GO:0032433; GO:0033674; GO:0043005; GO:0043235; GO:0044877; GO:0045121; GO:0046328; GO:0046777; GO:0048013; GO:0048593; GO:0050804; GO:0050965; GO:0051965; GO:0060326; GO:0060996; GO:0060997; GO:0061351; GO:0070372; GO:0098978; GO:1901214; GO:1902723; GO:1902725 20826 XM_044314588.1 290 149 191 280 252 NA NA NA NA NA NA 20827 XR_006392836.1 385 9 98 78 12 NA NA NA NA NA NA 20828 XM_044310935.1 33 153 30 38 83 NA NA NA NA NA NA 20829 XM_029326278.2 13 0 44 6 34 NA NA NA NA NA NA 20830 XM_044317539.1 1 6 6 5 4 C3ZQF9 1.28e-24 QRFP-like peptide receptor Branchiostoma floridae (Florida lancelet) (Amphioxus) cellular response to peptide [GO:1901653]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:1901653 20831 XM_044327346.1 258 511 403 342 574 NA NA NA NA NA NA 20832 XM_029324010.2 17 7 9 8 22 NA NA NA NA NA NA 20833 XM_029356273.2 5457 7738 5031 5807 3276 Q9JKK1 9.35e-73 Syntaxin-6 Mus musculus (Mouse) endocytic recycling [GO:0032456]; endosome organization [GO:0007032]; Golgi vesicle transport [GO:0048193]; intracellular protein transport [GO:0006886]; regulation of protein localization [GO:0032880]; retrograde transport, endosome to Golgi [GO:0042147]; synaptic vesicle to endosome fusion [GO:0016189]; vesicle docking [GO:0048278]; vesicle fusion [GO:0006906]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0000149; GO:0005484; GO:0005654; GO:0005769; GO:0005794; GO:0005802; GO:0005829; GO:0006886; GO:0006906; GO:0007032; GO:0008021; GO:0012505; GO:0016020; GO:0016189; GO:0016192; GO:0019905; GO:0030672; GO:0031201; GO:0032456; GO:0032588; GO:0032880; GO:0042147; GO:0045335; GO:0048193; GO:0048278; GO:0048471; GO:0055037; GO:0055038 20834 XM_044322985.1 55 39 55 39 116 NA NA NA NA NA NA 20835 XM_044324599.1 0 0 0 0 9 NA NA NA NA NA NA 20836 XM_029335812.2 0 0 0 0 6 NA NA NA NA NA NA 20837 XM_029338260.2 132 188 74 165 160 NA NA NA NA NA NA 20838 XM_029348384.2 395 461 266 719 406 NA NA NA NA NA NA 20839 XM_044309806.1 0 0 28 0 66 P49013 8.63e-55 Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374 20840 XM_044309806.1 0 0 28 0 66 P49013 1.56e-53 Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374 20841 XM_044309806.1 0 0 28 0 66 P49013 4.84e-49 Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374 20842 XM_044309806.1 0 0 28 0 66 P49013 7.81e-39 Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374 20843 XM_044309806.1 0 0 28 0 66 P49013 3.61e-37 Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374 20844 XM_044309806.1 0 0 28 0 66 P49013 5.19e-27 Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374 20845 XM_044315010.1 834 455 551 454 1511 O73787 0 Gamma-tubulin complex component 3 homolog (Gamma-ring complex protein 109) (Xgrip109) (x109p) Xenopus laevis (African clawed frog) microtubule nucleation [GO:0007020] GO:0000922; GO:0005813; GO:0005829; GO:0005874; GO:0007020; GO:0043015 20846 XR_006396437.1 102 30 24 61 84 NA NA NA NA NA NA 20847 XM_044324199.1 106 83 78 0 112 NA NA NA NA NA NA 20848 XR_006397790.1 15 0 65 181 0 NA NA NA NA NA NA 20849 XM_044317573.1 34 0 3 135 199 NA NA NA NA NA NA 20850 XM_044307621.1 846 790 172 808 240 NA NA NA NA NA NA 20851 XM_044323062.1 52 26 75 25 22 NA NA NA NA NA NA 20852 XM_044313650.1 113 0 33 0 0 Q924C1 4.4e-52 Exportin-5 (Exp5) (Ran-binding protein 21) Mus musculus (Mouse) positive regulation of post-transcriptional gene silencing by RNA [GO:1900370]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; RNA export from nucleus [GO:0006405] GO:0000049; GO:0003723; GO:0003729; GO:0005049; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006405; GO:0006611; GO:0016442; GO:0031267; GO:0035281; GO:0042565; GO:0070883; GO:1900370; GO:1905172 20853 XM_044319065.1 108 42 77 103 176 Q6MG55 1.08e-138 Phosphatidylserine lipase ABHD16A (EC 3.1.-.-) (Alpha/beta hydrolase domain-containing protein 16A) (Abhydrolase domain-containing protein 16A) (HLA-B-associated transcript 5 homolog) (Monoacylglycerol lipase ABHD16A) (EC 3.1.1.23) Rattus norvegicus (Rat) monoacylglycerol catabolic process [GO:0052651]; phosphatidylserine catabolic process [GO:0006660]; prostaglandin catabolic process [GO:1905344] GO:0004620; GO:0006660; GO:0008474; GO:0016020; GO:0047372; GO:0052651; GO:1905344 20854 XM_044325355.1 91 65 79 44 194 P48733 9.17e-26 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Bos taurus (Bovine) antibacterial innate immune response [GO:0140367]; defense response to Gram-negative bacterium [GO:0050829] GO:0000922; GO:0005201; GO:0005509; GO:0005576; GO:0005929; GO:0016020; GO:0016323; GO:0016324; GO:0031012; GO:0050829; GO:0060170; GO:0140367 20855 XM_044318085.1 237 135 11 64 43 NA NA NA NA NA NA 20856 XM_044320851.1 306 141 26 300 240 NA NA NA NA NA NA 20857 XM_044312792.1 433 327 200 471 378 Q9Y2X3 0 Nucleolar protein 58 (Nucleolar protein 5) Homo sapiens (Human) rRNA processing [GO:0006364]; snoRNA localization [GO:0048254] GO:0001094; GO:0001650; GO:0003723; GO:0005654; GO:0005730; GO:0005732; GO:0005829; GO:0006364; GO:0015030; GO:0016020; GO:0030515; GO:0031428; GO:0032040; GO:0048254; GO:0051117; GO:0070761 20858 XR_006393577.1 443 150 304 476 646 NA NA NA NA NA NA 20859 XM_029335753.2 23 267 204 464 233 O62809 1.6e-33 Orexin receptor type 2 (Ox-2-R) (Ox2-R) (Ox2R) (Hypocretin receptor type 2) Sus scrofa (Pig) circadian sleep/wake cycle process [GO:0022410]; feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; locomotion [GO:0040011]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; regulation of circadian sleep/wake cycle, wakefulness [GO:0010840]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0004930; GO:0005886; GO:0007186; GO:0007200; GO:0007218; GO:0007631; GO:0010840; GO:0016499; GO:0022410; GO:0040011; GO:0051480 20860 XM_029339788.2 616 278 242 216 386 Q0VGW6 0 Solute carrier family 12 member 9 (Cation-chloride cotransporter-interacting protein 1) Xenopus laevis (African clawed frog) NA GO:0005886; GO:0015377 20861 XR_006397690.1 484 1266 172 582 1257 NA NA NA NA NA NA 20862 XM_029332182.2 1216 725 695 1152 1328 Q5SZK8 0 FRAS1-related extracellular matrix protein 2 (ECM3 homolog) Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell communication [GO:0007154]; embryonic digit morphogenesis [GO:0042733]; eye development [GO:0001654]; heart development [GO:0007507]; inner ear development [GO:0048839]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009] GO:0001654; GO:0001822; GO:0002009; GO:0005604; GO:0005886; GO:0007154; GO:0007155; GO:0007507; GO:0009653; GO:0042733; GO:0046872; GO:0048839; GO:0062023; GO:0070062 20863 XM_029324149.2 652 431 390 778 728 Q5RBG4 0 Histone acetyltransferase KAT5 (EC 2.3.1.48) (60 kDa Tat-interactive protein) (Tip60) (Histone acetyltransferase HTATIP) (Lysine acetyltransferase 5) (Protein 2-hydroxyisobutyryltransferase KAT5) (EC 2.3.1.-) (Protein acetyltransferase KAT5) (EC 2.3.1.-) (Protein crotonyltransferase KAT5) (EC 2.3.1.-) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cellular response to DNA damage stimulus [GO:0006974]; cellular response to glucose starvation [GO:0042149]; chromatin organization [GO:0006325]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; establishment of mitotic spindle orientation [GO:0000132]; histone acetylation [GO:0016573]; innate immune response [GO:0045087]; lipid droplet disassembly [GO:1905691]; nucleotide-excision repair [GO:0006289]; peptidyl-lysine acetylation [GO:0018394]; positive regulation of attachment of mitotic spindle microtubules to kinetochore [GO:1902425]; positive regulation of autophagy [GO:0010508]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of mitotic sister chromatid segregation [GO:0062033]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of regulatory T cell differentiation [GO:0045591]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of triglyceride biosynthetic process [GO:0010867]; regulation of hematopoietic stem cell differentiation [GO:1902036]; spermatid development [GO:0007286] GO:0000132; GO:0000724; GO:0000776; GO:0000812; GO:0000922; GO:0003682; GO:0003713; GO:0004402; GO:0005634; GO:0005730; GO:0005737; GO:0006289; GO:0006302; GO:0006325; GO:0006974; GO:0006978; GO:0007286; GO:0010508; GO:0010867; GO:0016573; GO:0018394; GO:0032777; GO:0035267; GO:0042149; GO:0042753; GO:0043998; GO:0045087; GO:0045591; GO:0045663; GO:0045893; GO:0045944; GO:0046872; GO:0048471; GO:0061733; GO:0062033; GO:0106226; GO:0140064; GO:0140065; GO:1902036; GO:1902425; GO:1905168; GO:1905691 20864 XM_029335132.2 1163 345 421 567 983 NA NA NA NA NA NA 20865 XM_029338133.2 814 775 335 832 981 Q9GZN1 5.03e-175 Actin-related protein 6 (hArp6) (hARPX) Homo sapiens (Human) negative regulation of transcription by RNA polymerase I [GO:0016479]; nucleolus organization [GO:0007000]; positive regulation of transcription by RNA polymerase I [GO:0045943]; regulation of DNA-templated transcription [GO:0006355] GO:0000786; GO:0000812; GO:0005634; GO:0005730; GO:0005737; GO:0005856; GO:0006355; GO:0007000; GO:0016479; GO:0031491; GO:0045943 20866 XM_044316308.1 1 0 12 0 82 NA NA NA NA NA NA 20867 XM_029335969.2 59 27 28 26 21 NA NA NA NA NA NA 20868 XM_044317672.1 50 63 49 27 11 Q5SPC5 0 Otoferlin (Fer-1-like protein 2) Danio rerio (Zebrafish) (Brachydanio rerio) neuromuscular process controlling balance [GO:0050885]; plasma membrane organization [GO:0007009]; response to auditory stimulus [GO:0010996]; sensory perception of sound [GO:0007605]; startle response [GO:0001964]; synaptic vesicle exocytosis [GO:0016079]; synaptic vesicle priming [GO:0016082] GO:0000139; GO:0001964; GO:0005509; GO:0005789; GO:0007009; GO:0007605; GO:0010996; GO:0016079; GO:0016082; GO:0016323; GO:0030672; GO:0035612; GO:0042995; GO:0048787; GO:0050885 20869 XM_044317672.1 50 63 49 27 11 Q5SPC5 2.26e-106 Otoferlin (Fer-1-like protein 2) Danio rerio (Zebrafish) (Brachydanio rerio) neuromuscular process controlling balance [GO:0050885]; plasma membrane organization [GO:0007009]; response to auditory stimulus [GO:0010996]; sensory perception of sound [GO:0007605]; startle response [GO:0001964]; synaptic vesicle exocytosis [GO:0016079]; synaptic vesicle priming [GO:0016082] GO:0000139; GO:0001964; GO:0005509; GO:0005789; GO:0007009; GO:0007605; GO:0010996; GO:0016079; GO:0016082; GO:0016323; GO:0030672; GO:0035612; GO:0042995; GO:0048787; GO:0050885 20870 XM_044317672.1 50 63 49 27 11 Q5SPC5 2.26e-106 Otoferlin (Fer-1-like protein 2) Danio rerio (Zebrafish) (Brachydanio rerio) neuromuscular process controlling balance [GO:0050885]; plasma membrane organization [GO:0007009]; response to auditory stimulus [GO:0010996]; sensory perception of sound [GO:0007605]; startle response [GO:0001964]; synaptic vesicle exocytosis [GO:0016079]; synaptic vesicle priming [GO:0016082] GO:0000139; GO:0001964; GO:0005509; GO:0005789; GO:0007009; GO:0007605; GO:0010996; GO:0016079; GO:0016082; GO:0016323; GO:0030672; GO:0035612; GO:0042995; GO:0048787; GO:0050885 20871 XR_006394484.1 41 99 0 143 123 NA NA NA NA NA NA 20872 XM_029329629.2 997 469 751 225 744 NA NA NA NA NA NA 20873 XM_029340386.2 32 15 0 113 0 E9QAT4 1.12e-45 Protein transport protein Sec16A (SEC16 homolog A) (p250) Mus musculus (Mouse) autophagy [GO:0006914]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; Golgi to plasma membrane transport [GO:0006893]; protein exit from endoplasmic reticulum [GO:0032527]; protein localization to endoplasmic reticulum exit site [GO:0070973]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; response to endoplasmic reticulum stress [GO:0034976] GO:0000139; GO:0005789; GO:0005829; GO:0006888; GO:0006893; GO:0006914; GO:0007029; GO:0007030; GO:0012507; GO:0031090; GO:0032527; GO:0034976; GO:0048208; GO:0048471; GO:0050821; GO:0070971; GO:0070973; GO:0072659 20874 XM_029334423.2 0 2 0 9 0 Q91981 1.83e-32 Homeobox protein OTX2 (zOTX2) (Orthodenticle homolog 2) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to alcohol [GO:0097306]; cerebellum development [GO:0021549]; hindbrain development [GO:0030902]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; regulation of transcription by RNA polymerase II [GO:0006357]; retinal pigment epithelium development [GO:0003406] GO:0000978; GO:0000981; GO:0003406; GO:0005634; GO:0006357; GO:0021549; GO:0030901; GO:0030902; GO:0030917; GO:0097306 20875 XM_029346894.2 910 698 234 459 1724 Q23808 1.69e-53 Aquaporin AQPcic Cicadella viridis (Green leafhopper) NA GO:0015267; GO:0016020 20876 XM_044308105.1 0 9 0 9 0 NA NA NA NA NA NA 20877 XM_029348771.2 10770 13242 9833 11416 5674 Q5RDN9 4.31e-73 Protein yippee-like 2 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0005730; GO:0046872 20878 XR_003825403.2 229 272 137 320 369 NA NA NA NA NA NA 20879 XM_044326054.1 51 16 14 47 33 NA NA NA NA NA NA 20880 XM_029342079.2 15 0 0 2 14 NA NA NA NA NA NA 20881 XR_006396130.1 120 68 69 46 180 NA NA NA NA NA NA 20882 XM_044322207.1 0 310 314 5 310 Q5F499 0 Dynamin-like 120 kDa protein, mitochondrial (EC 3.6.5.5) (Optic atrophy protein 1 homolog) [Cleaved into: Dynamin-like 120 kDa protein, form S1] Gallus gallus (Chicken) apoptotic process [GO:0006915]; GTP metabolic process [GO:0046039]; membrane tubulation [GO:0097749]; mitochondrial fusion [GO:0008053] GO:0003924; GO:0005525; GO:0005737; GO:0005743; GO:0005758; GO:0005874; GO:0006915; GO:0008017; GO:0008053; GO:0016020; GO:0031966; GO:0046039; GO:0070300; GO:0097749; GO:1901612 20883 XR_006395671.1 1 5 7 1 15 NA NA NA NA NA NA 20884 XM_044310360.1 229 89 77 308 403 NA NA NA NA NA NA 20885 XR_003825689.2 11 0 0 0 0 NA NA NA NA NA NA 20886 XR_006393952.1 11 20 21 55 64 NA NA NA NA NA NA 20887 XR_006397508.1 48 14 44 75 55 NA NA NA NA NA NA 20888 XM_029341579.2 208 94 73 94 111 NA NA NA NA NA NA 20889 XM_029358427.2 2 0 7 0 10 NA NA NA NA NA NA 20890 XM_044323873.1 11 14 0 0 0 Q8BWN8 2.71e-82 Peroxisomal succinyl-coenzyme A thioesterase (EC 3.1.2.3) (Acyl-coenzyme A thioesterase 4) (Acyl-CoA thioesterase 4) (PTE-2b) (Peroxisomal acyl coenzyme A thioester hydrolase Ib) (Peroxisomal long-chain acyl-CoA thioesterase Ib) (PTE-Ib) Mus musculus (Mouse) acyl-CoA metabolic process [GO:0006637]; dicarboxylic acid catabolic process [GO:0043649]; dicarboxylic acid metabolic process [GO:0043648]; fatty acid metabolic process [GO:0006631]; long-chain fatty acid metabolic process [GO:0001676]; saturated monocarboxylic acid metabolic process [GO:0032788]; short-chain fatty acid metabolic process [GO:0046459]; succinyl-CoA metabolic process [GO:0006104]; unsaturated monocarboxylic acid metabolic process [GO:0032789]; very long-chain fatty acid metabolic process [GO:0000038] GO:0000038; GO:0001676; GO:0004778; GO:0005777; GO:0006104; GO:0006631; GO:0006637; GO:0032788; GO:0032789; GO:0043648; GO:0043649; GO:0044466; GO:0046459; GO:0047617 20891 XM_029331272.2 715 625 338 528 365 Q5W0A0 2.64e-23 Glutamate-rich protein 6B (Protein FAM194B) Homo sapiens (Human) NA NA 20892 XM_029338709.2 0 27 0 23 76 NA NA NA NA NA NA 20893 XM_029347214.2 1868 1153 810 1188 643 NA NA NA NA NA NA 20894 XR_003827996.2 76 127 201 91 188 NA NA NA NA NA NA 20895 XM_044317729.1 331 139 222 291 290 A0A5F9C6I2 1.03e-27 NA NA NA NA 20896 XM_044326407.1 251 130 104 366 106 NA NA NA NA NA NA 20897 XR_006392669.1 127 91 13 37 96 NA NA NA NA NA NA 20898 XM_029335151.2 3982 2346 1574 3456 3860 Q28CQ4 7.78e-95 SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell division [GO:0051301]; chromosome segregation [GO:0007059]; protein sumoylation [GO:0016925] GO:0005524; GO:0005634; GO:0007059; GO:0016740; GO:0016925; GO:0051301 20899 XM_029330368.2 0 38 0 39 6 O42357 3.53e-24 Retinal homeobox protein Rx2 Danio rerio (Zebrafish) (Brachydanio rerio) camera-type eye photoreceptor cell differentiation [GO:0060219]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0045944; GO:0060219 20900 XR_006391404.1 16 13 5 26 0 NA NA NA NA NA NA 20901 XM_044318751.1 0 0 0 39 0 NA NA NA NA NA NA 20902 XM_029336195.2 258 424 106 185 114 NA NA NA NA NA NA 20903 XM_029347939.2 751 584 193 461 274 NA NA NA NA NA NA 20904 XM_029334288.2 59 20 39 24 103 NA NA NA NA NA NA 20905 XM_044326685.1 101 99 74 119 488 Q09M02 9.52e-136 Cytosolic carboxypeptidase-like protein 5 (EC 3.4.17.-) (EC 3.4.17.24) (ATP/GTP-binding protein-like 5) (Protein deglutamylase CCP5) Mus musculus (Mouse) C-terminal protein deglutamylation [GO:0035609]; defense response to virus [GO:0051607]; protein branching point deglutamylation [GO:0035611]; protein deglutamylation [GO:0035608]; protein side chain deglutamylation [GO:0035610]; proteolysis [GO:0006508] GO:0004181; GO:0005634; GO:0005737; GO:0005829; GO:0006508; GO:0008270; GO:0015630; GO:0015631; GO:0030496; GO:0035608; GO:0035609; GO:0035610; GO:0035611; GO:0045171; GO:0051607; GO:0072686 20906 XM_044326685.1 101 99 74 119 488 Q09M02 1.08e-61 Cytosolic carboxypeptidase-like protein 5 (EC 3.4.17.-) (EC 3.4.17.24) (ATP/GTP-binding protein-like 5) (Protein deglutamylase CCP5) Mus musculus (Mouse) C-terminal protein deglutamylation [GO:0035609]; defense response to virus [GO:0051607]; protein branching point deglutamylation [GO:0035611]; protein deglutamylation [GO:0035608]; protein side chain deglutamylation [GO:0035610]; proteolysis [GO:0006508] GO:0004181; GO:0005634; GO:0005737; GO:0005829; GO:0006508; GO:0008270; GO:0015630; GO:0015631; GO:0030496; GO:0035608; GO:0035609; GO:0035610; GO:0035611; GO:0045171; GO:0051607; GO:0072686 20907 XM_044322630.1 1 7 0 4 1 NA NA NA NA NA NA 20908 XM_029338802.2 161 0 21 0 61 B3EWZ7 2.13e-68 Threonine-rich protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 20909 XM_044323290.1 91 24 44 9 0 Q5R5U3 3.83e-83 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 20910 XM_044323290.1 91 24 44 9 0 Q5R5U3 1e-82 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 20911 XM_044323290.1 91 24 44 9 0 Q5R5U3 6.7e-79 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 20912 XM_044323290.1 91 24 44 9 0 Q5R5U3 4.09e-78 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 20913 XM_044323290.1 91 24 44 9 0 Q5R5U3 8.76e-72 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 20914 XM_044323290.1 91 24 44 9 0 Q5R5U3 6.01e-62 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 20915 XM_044323290.1 91 24 44 9 0 Q5R5U3 1.92e-60 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 20916 XR_006392381.1 463 435 365 527 521 P31836 2.38e-38 Neural cell adhesion molecule 1 (N-CAM-1) (NCAM-1) Bos taurus (Bovine) axon guidance [GO:0007411]; dendrite self-avoidance [GO:0070593]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005886; GO:0007156; GO:0007411; GO:0030424; GO:0070593; GO:0098632 20917 XM_044317791.1 177 349 199 182 141 P55809 0 Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial (SCOT) (EC 2.8.3.5) (3-oxoacid CoA-transferase 1) (Somatic-type succinyl-CoA:3-oxoacid CoA-transferase) (SCOT-s) (Succinyl-CoA:3-oxoacid CoA transferase) Homo sapiens (Human) adipose tissue development [GO:0060612]; brain development [GO:0007420]; cellular ketone body metabolic process [GO:0046950]; heart development [GO:0007507]; ketone body catabolic process [GO:0046952]; ketone catabolic process [GO:0042182]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; response to activity [GO:0014823]; response to ethanol [GO:0045471]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; response to starvation [GO:0042594]; response to xenobiotic stimulus [GO:0009410] GO:0005739; GO:0005759; GO:0007420; GO:0007507; GO:0007584; GO:0008260; GO:0008410; GO:0009410; GO:0009725; GO:0014823; GO:0035774; GO:0042182; GO:0042594; GO:0042802; GO:0045471; GO:0046950; GO:0046952; GO:0060612 20918 XM_044317791.1 177 349 199 182 141 P55809 4.36e-27 Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial (SCOT) (EC 2.8.3.5) (3-oxoacid CoA-transferase 1) (Somatic-type succinyl-CoA:3-oxoacid CoA-transferase) (SCOT-s) (Succinyl-CoA:3-oxoacid CoA transferase) Homo sapiens (Human) adipose tissue development [GO:0060612]; brain development [GO:0007420]; cellular ketone body metabolic process [GO:0046950]; heart development [GO:0007507]; ketone body catabolic process [GO:0046952]; ketone catabolic process [GO:0042182]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; response to activity [GO:0014823]; response to ethanol [GO:0045471]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; response to starvation [GO:0042594]; response to xenobiotic stimulus [GO:0009410] GO:0005739; GO:0005759; GO:0007420; GO:0007507; GO:0007584; GO:0008260; GO:0008410; GO:0009410; GO:0009725; GO:0014823; GO:0035774; GO:0042182; GO:0042594; GO:0042802; GO:0045471; GO:0046950; GO:0046952; GO:0060612 20919 XM_029345633.2 17 0 0 0 7 Q32M08 2.43e-106 tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like (EC 1.3.1.90) (tRNA-dihydrouridine synthase 4-like) Mus musculus (Mouse) tRNA dihydrouridine synthesis [GO:0002943] GO:0002943; GO:0017150; GO:0050660 20920 XM_044312036.1 12 0 0 0 128 NA NA NA NA NA NA 20921 XM_029335987.2 772 756 376 678 848 P04047 4.09e-81 Thymidine kinase, cytosolic (EC 2.7.1.21) Gallus gallus (Chicken) DNA biosynthetic process [GO:0071897]; phosphorylation [GO:0016310]; protein homotetramerization [GO:0051289]; thymidine metabolic process [GO:0046104] GO:0004797; GO:0005524; GO:0005737; GO:0008270; GO:0016310; GO:0042802; GO:0046104; GO:0051289; GO:0071897 20922 XM_044327205.1 319 5 29 8 48 Q9LUE3 6.67e-28 Bidirectional sugar transporter SWEET10 (AtSWEET10) (Protein SUGARS WILL EVENTUALLY BE EXPORTED TRANSPORTERS 10) Arabidopsis thaliana (Mouse-ear cress) carbohydrate transport [GO:0008643]; long-day photoperiodism [GO:0048571]; sucrose transport [GO:0015770] GO:0005886; GO:0008515; GO:0008643; GO:0015770; GO:0016020; GO:0048571; GO:0051119 20923 XM_044308367.1 1431 1068 560 895 563 Q9UPZ9 2.21e-171 Serine/threonine-protein kinase ICK (EC 2.7.11.1) (Ciliogenesis associated kinase 1) (Intestinal cell kinase) (hICK) (Laryngeal cancer kinase 2) (LCK2) (MAK-related kinase) (MRK) Homo sapiens (Human) cilium assembly [GO:0060271]; intracellular signal transduction [GO:0035556]; intraciliary anterograde transport [GO:0035720]; intraciliary retrograde transport [GO:0035721]; intraciliary transport [GO:0042073]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165] GO:0000287; GO:0001650; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0005929; GO:0006468; GO:0007165; GO:0035556; GO:0035720; GO:0035721; GO:0036064; GO:0042073; GO:0060271; GO:0097542; GO:0097546; GO:0106310 20924 XM_044325526.1 240 187 143 329 167 Q9H0J9 1.36e-78 Protein mono-ADP-ribosyltransferase PARP12 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 12) (ARTD12) (Poly [ADP-ribose] polymerase 12) (PARP-12) (Zinc finger CCCH domain-containing protein 1) Homo sapiens (Human) protein auto-ADP-ribosylation [GO:0070213] GO:0003723; GO:0003950; GO:0005634; GO:0016779; GO:0046872; GO:0070213; GO:0140803; GO:1990404 20925 XM_029347782.2 1053 625 1472 688 2975 NA NA NA NA NA NA 20926 XR_003824610.2 7 5 0 21 37 NA NA NA NA NA NA 20927 XR_006397304.1 5 0 7 14 7 NA NA NA NA NA NA 20928 XM_044320450.1 82 131 73 0 58 NA NA NA NA NA NA 20929 XM_029356134.2 25 35 6 48 59 NA NA NA NA NA NA 20930 XM_029343320.2 61 23 66 21 177 O35214 3.99e-27 Visual pigment-like receptor peropsin Mus musculus (Mouse) cellular response to light stimulus [GO:0071482]; G protein-coupled receptor signaling pathway [GO:0007186]; phototransduction [GO:0007602]; visual perception [GO:0007601] GO:0001750; GO:0005886; GO:0007186; GO:0007601; GO:0007602; GO:0008020; GO:0071482 20931 XM_029343004.2 971 502 341 692 790 Q5RFQ0 2.86e-95 rRNA-processing protein FCF1 homolog Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000480]; endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000447] GO:0000447; GO:0000480; GO:0005730; GO:0032040 20932 XR_003824245.2 10 25 0 3 54 Q9QX47 2.05e-58 Protein SON (Negative regulatory element-binding protein) (NRE-binding protein) Mus musculus (Mouse) microtubule cytoskeleton organization [GO:0000226]; mitotic cytokinesis [GO:0000281]; mRNA processing [GO:0006397]; negative regulation of apoptotic process [GO:0043066]; regulation of cell cycle [GO:0051726]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380] GO:0000226; GO:0000281; GO:0003677; GO:0003723; GO:0006397; GO:0008380; GO:0016607; GO:0043066; GO:0043484; GO:0048024; GO:0050733; GO:0051726 20933 XM_044319014.1 297 0 185 161 0 Q09328 0 Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (EC 2.4.1.155) (Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase V) (GlcNAc-T V) (GNT-V) (Mannoside acetylglucosaminyltransferase 5) (N-acetylglucosaminyl-transferase V) [Cleaved into: Secreted alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (Secreted beta-1,6-N-acetylglucosaminyltransferase V) (Secreted GNT-V)] Homo sapiens (Human) negative regulation of protein tyrosine phosphatase activity [GO:1903614]; positive regulation of cell migration [GO:0030335]; positive regulation of receptor signaling pathway via STAT [GO:1904894]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279]; viral protein processing [GO:0019082] GO:0000139; GO:0004864; GO:0005794; GO:0006487; GO:0016020; GO:0018279; GO:0019082; GO:0030144; GO:0030145; GO:0030335; GO:0070062; GO:1903614; GO:1904894 20934 XM_044314487.1 27 21 37 10 87 NA NA NA NA NA NA 20935 XM_044328993.1 52 0 42 39 84 F1R332 5.68e-25 Galanin receptor 2a Danio rerio (Zebrafish) (Brachydanio rerio) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; neuropeptide signaling pathway [GO:0007218] GO:0004966; GO:0005886; GO:0007188; GO:0007218; GO:0008528 20936 XM_044309685.1 7 3 0 0 0 NA NA NA NA NA NA 20937 XM_044318034.1 0 0 23 0 0 NA NA NA NA NA NA 20938 XM_029343334.2 826 329 375 566 708 Q5RF77 3.59e-110 E3 ubiquitin-protein ligase CHFR (EC 2.3.2.27) (Checkpoint with forkhead and RING finger domains protein) (RING-type E3 ubiquitin transferase CHFR) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cell division [GO:0051301]; mitotic G2/M transition checkpoint [GO:0044818]; modification-dependent protein catabolic process [GO:0019941]; protein polyubiquitination [GO:0000209] GO:0000166; GO:0000209; GO:0004842; GO:0005634; GO:0016605; GO:0019941; GO:0044818; GO:0046872; GO:0051301 20939 XR_003823677.2 51 63 43 38 120 NA NA NA NA NA NA 20940 XM_044310301.1 0 6 8 10 6 NA NA NA NA NA NA 20941 XR_006396070.1 42 0 0 62 66 NA NA NA NA NA NA 20942 XM_044314311.1 1370 546 376 1110 752 Q5ZLD2 2.42e-36 DEP domain-containing protein 1B Gallus gallus (Chicken) intracellular signal transduction [GO:0035556]; positive regulation of Wnt signaling pathway [GO:0030177] GO:0005096; GO:0030177; GO:0035556 20943 XM_044306750.1 686 151 313 130 109 NA NA NA NA NA NA 20944 XM_029349863.2 125 265 44 296 48 P50211 1.85e-123 Insulin gene enhancer protein ISL-1 (Islet-1) Gallus gallus (Chicken) atrial septum morphogenesis [GO:0060413]; axonogenesis [GO:0007409]; canonical Wnt signaling pathway [GO:0060070]; cardiac cell fate determination [GO:0060913]; cardiac muscle cell myoblast differentiation [GO:0060379]; cardiac right ventricle morphogenesis [GO:0003215]; cell population proliferation [GO:0008283]; endocardial cushion morphogenesis [GO:0003203]; heart development [GO:0007507]; innervation [GO:0060384]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural crest cell migration [GO:0001755]; neuron fate specification [GO:0048665]; outflow tract septum morphogenesis [GO:0003148]; pancreas development [GO:0031016]; peripheral nervous system neuron axonogenesis [GO:0048936]; pharyngeal system development [GO:0060037]; pituitary gland development [GO:0021983]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA binding [GO:0043388]; positive regulation of granulocyte colony-stimulating factor production [GO:0071657]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of histone acetylation [GO:0035066]; positive regulation of insulin secretion [GO:0032024]; positive regulation of interleukin-1 alpha production [GO:0032730]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type II interferon production [GO:0032729]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of secondary heart field cardioblast proliferation [GO:0003266]; regulation of transcription by RNA polymerase II [GO:0006357]; retinal ganglion cell axon guidance [GO:0031290]; secondary heart field specification [GO:0003139]; sensory system development [GO:0048880]; sinoatrial node cell development [GO:0060931]; spinal cord motor neuron cell fate specification [GO:0021520]; transcription by RNA polymerase II [GO:0006366]; trigeminal nerve development [GO:0021559]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; visceral motor neuron differentiation [GO:0021524] GO:0000122; GO:0000785; GO:0000978; GO:0000981; GO:0000987; GO:0001228; GO:0001755; GO:0003139; GO:0003148; GO:0003203; GO:0003215; GO:0003266; GO:0005634; GO:0006357; GO:0006366; GO:0007409; GO:0007507; GO:0008283; GO:0008284; GO:0010575; GO:0021520; GO:0021524; GO:0021559; GO:0021983; GO:0031016; GO:0031290; GO:0032024; GO:0032725; GO:0032729; GO:0032730; GO:0032731; GO:0032735; GO:0032755; GO:0032760; GO:0035066; GO:0042531; GO:0043388; GO:0043425; GO:0043524; GO:0045597; GO:0045665; GO:0045766; GO:0045892; GO:0045944; GO:0046872; GO:0048665; GO:0048880; GO:0048936; GO:0050728; GO:0055010; GO:0060037; GO:0060070; GO:0060379; GO:0060384; GO:0060413; GO:0060913; GO:0060931; GO:0061629; GO:0071657; GO:0086091; GO:0090090; GO:1990841 20945 XM_029336619.2 125 12 63 287 38 NA NA NA NA NA NA 20946 XR_006391580.1 118 77 139 117 385 NA NA NA NA NA NA 20947 XM_044328075.1 0 0 0 0 6 NA NA NA NA NA NA 20948 XM_044308447.1 583 399 246 409 526 Q9UBR1 0 Beta-ureidopropionase (EC 3.5.1.6) (BUP-1) (Beta-alanine synthase) (N-carbamoyl-beta-alanine amidohydrolase) Homo sapiens (Human) beta-alanine biosynthetic process via 3-ureidopropionate [GO:0033396]; CMP catabolic process [GO:0006248]; dCMP catabolic process [GO:0006249]; dUMP catabolic process [GO:0046079]; in utero embryonic development [GO:0001701]; liver development [GO:0001889]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; pyrimidine nucleoside catabolic process [GO:0046135]; UMP catabolic process [GO:0046050] GO:0001701; GO:0001889; GO:0003837; GO:0005829; GO:0006248; GO:0006249; GO:0016811; GO:0033396; GO:0042803; GO:0046050; GO:0046079; GO:0046135; GO:0051260; GO:0051289; GO:0070062 20949 XM_029345157.2 8648 2218 3070 2374 1982 P35061 4.28e-62 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 20950 XM_029357785.2 1219 1102 591 771 733 Q96EH3 1.91e-29 Mitochondrial assembly of ribosomal large subunit protein 1 Homo sapiens (Human) negative regulation of mitochondrial translation [GO:0070130]; negative regulation of ribosome biogenesis [GO:0090071]; negative regulation of translation [GO:0017148]; ribosomal large subunit biogenesis [GO:0042273] GO:0005739; GO:0005759; GO:0005829; GO:0017148; GO:0042273; GO:0043023; GO:0070130; GO:0090071 20951 XM_029351838.2 1315 1247 758 1377 1136 P61166 4.41e-30 Transmembrane protein 258 (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TMEM258) (Oligosaccharyl transferase subunit TMEM258) Mus musculus (Mouse) epithelial cell apoptotic process [GO:1904019]; inflammatory response [GO:0006954]; protein N-linked glycosylation [GO:0006487]; protein secretion [GO:0009306]; response to endoplasmic reticulum stress [GO:0034976] GO:0005737; GO:0005783; GO:0005789; GO:0006487; GO:0006954; GO:0008250; GO:0009306; GO:0016020; GO:0032991; GO:0034976; GO:0034998; GO:0043227; GO:0062062; GO:1904019 20952 XM_044309097.1 0 0 0 470 0 NA NA NA NA NA NA 20953 XM_044314387.1 7 3 19 10 92 NA NA NA NA NA NA 20954 XM_029336453.2 130 142 73 234 130 Q91ZW6 2.38e-78 Trimethyllysine dioxygenase, mitochondrial (EC 1.14.11.8) (Epsilon-trimethyllysine 2-oxoglutarate dioxygenase) (TML hydroxylase) (TML-alpha-ketoglutarate dioxygenase) (TML dioxygenase) (TMLD) Rattus norvegicus (Rat) carnitine biosynthetic process [GO:0045329] GO:0005506; GO:0005739; GO:0005759; GO:0016702; GO:0045329; GO:0050353 20955 XM_044317461.1 3 6 0 17 0 NA NA NA NA NA NA 20956 XM_044311091.1 0 3 3 0 8 NA NA NA NA NA NA 20957 XM_029345166.2 1063 1172 794 1860 1529 Q96PQ7 0 Kelch-like protein 5 Homo sapiens (Human) NA GO:0003779; GO:0005737; GO:0005829; GO:0005856 20958 XM_029338913.2 257 95 123 162 335 NA NA NA NA NA NA 20959 XM_029340505.2 2318 2126 1330 2254 2164 Q5E9S2 2.85e-27 Nuclear transcription factor Y subunit alpha (CAAT box DNA-binding protein subunit A) (Nuclear transcription factor Y subunit A) (NF-YA) Bos taurus (Bovine) histone H3-K4 trimethylation [GO:0080182]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of histone acetylation [GO:0035065]; regulation of transcription by RNA polymerase II [GO:0006357]; rhythmic process [GO:0048511] GO:0000978; GO:0000981; GO:0003677; GO:0005634; GO:0005654; GO:0006355; GO:0006357; GO:0016602; GO:0032993; GO:0035065; GO:0045893; GO:0045944; GO:0048511; GO:0080182 20960 XM_044326322.1 0 0 28 616 0 B3EWZ6 6.24e-125 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 20961 XM_044326322.1 0 0 28 616 0 B3EWZ6 2.65e-122 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 20962 XM_044326322.1 0 0 28 616 0 B3EWZ6 5.8e-122 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 20963 XM_044326322.1 0 0 28 616 0 B3EWZ6 2.62e-118 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 20964 XM_044326322.1 0 0 28 616 0 B3EWZ6 6.12e-112 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 20965 XM_044326322.1 0 0 28 616 0 B3EWZ6 4.79e-110 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 20966 XM_044326322.1 0 0 28 616 0 B3EWZ6 1.4e-107 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 20967 XM_044326322.1 0 0 28 616 0 B3EWZ6 6.13e-106 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 20968 XM_044326322.1 0 0 28 616 0 B3EWZ6 1.49e-95 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 20969 XM_044326322.1 0 0 28 616 0 B3EWZ6 9.74e-93 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 20970 XM_044326322.1 0 0 28 616 0 B3EWZ6 5.2e-80 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 20971 XM_044326322.1 0 0 28 616 0 B3EWZ6 5.59e-79 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 20972 XM_044326322.1 0 0 28 616 0 B3EWZ6 1.46e-74 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 20973 XM_044326322.1 0 0 28 616 0 B3EWZ6 2.92e-74 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 20974 XM_044326322.1 0 0 28 616 0 B3EWZ6 2.76e-73 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 20975 XM_044326322.1 0 0 28 616 0 B3EWZ6 1.87e-70 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 20976 XM_044326322.1 0 0 28 616 0 B3EWZ6 4.52e-70 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 20977 XM_044326322.1 0 0 28 616 0 B3EWZ6 4.71e-63 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 20978 XM_044326322.1 0 0 28 616 0 B3EWZ6 2.06e-62 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 20979 XM_044326322.1 0 0 28 616 0 B3EWZ6 2.88e-46 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 20980 XM_044326322.1 0 0 28 616 0 B3EWZ6 3.17e-22 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 20981 XM_044314469.1 86 21 60 59 109 NA NA NA NA NA NA 20982 XR_006394705.1 12 25 2 44 18 NA NA NA NA NA NA 20983 XM_029342612.2 677 483 462 720 715 A2RRU4 1.9e-116 Sterol regulatory element-binding protein cleavage-activating protein (SCAP) (SREBP cleavage-activating protein) Rattus norvegicus (Rat) aging [GO:0007568]; cellular lipid metabolic process [GO:0044255]; cholesterol metabolic process [GO:0008203]; COPII-coated vesicle cargo loading [GO:0090110]; immune response [GO:0006955]; positive regulation of cholesterol biosynthetic process [GO:0045542]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of fatty acid biosynthetic process [GO:0042304]; regulation of fatty acid metabolic process [GO:0019217]; response to hypoxia [GO:0001666]; response to insulin [GO:0032868]; SREBP signaling pathway [GO:0032933] GO:0000139; GO:0001666; GO:0005789; GO:0006955; GO:0007568; GO:0008203; GO:0012507; GO:0019217; GO:0032868; GO:0032933; GO:0032934; GO:0032936; GO:0032991; GO:0042304; GO:0043231; GO:0044255; GO:0044877; GO:0045540; GO:0045542; GO:0090110 20984 XM_029342612.2 677 483 462 720 715 A2RRU4 1.35e-53 Sterol regulatory element-binding protein cleavage-activating protein (SCAP) (SREBP cleavage-activating protein) Rattus norvegicus (Rat) aging [GO:0007568]; cellular lipid metabolic process [GO:0044255]; cholesterol metabolic process [GO:0008203]; COPII-coated vesicle cargo loading [GO:0090110]; immune response [GO:0006955]; positive regulation of cholesterol biosynthetic process [GO:0045542]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of fatty acid biosynthetic process [GO:0042304]; regulation of fatty acid metabolic process [GO:0019217]; response to hypoxia [GO:0001666]; response to insulin [GO:0032868]; SREBP signaling pathway [GO:0032933] GO:0000139; GO:0001666; GO:0005789; GO:0006955; GO:0007568; GO:0008203; GO:0012507; GO:0019217; GO:0032868; GO:0032933; GO:0032934; GO:0032936; GO:0032991; GO:0042304; GO:0043231; GO:0044255; GO:0044877; GO:0045540; GO:0045542; GO:0090110 20985 XR_006395364.1 378 449 326 798 774 NA NA NA NA NA NA 20986 XM_029339506.2 0 14 45 16 39 NA NA NA NA NA NA 20987 XR_006392793.1 1436 979 2155 1544 7287 NA NA NA NA NA NA 20988 XM_044308404.1 0 0 0 7 13 NA NA NA NA NA NA 20989 XM_029329774.2 0 143 0 0 18 P79134 1.06e-72 Annexin A6 (Annexin VI) (Annexin-6) Bos taurus (Bovine) apoptotic signaling pathway [GO:0097190]; biomineral tissue development [GO:0031214]; calcium ion import [GO:0070509]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; growth plate cartilage chondrocyte differentiation [GO:0003418]; mitochondrial calcium ion homeostasis [GO:0051560]; negative regulation of sequestering of calcium ion [GO:0051283]; neural crest cell migration [GO:0001755]; plasma membrane repair [GO:0001778]; regulation of muscle contraction [GO:0006937] GO:0001725; GO:0001755; GO:0001778; GO:0001786; GO:0003418; GO:0005262; GO:0005509; GO:0005525; GO:0005544; GO:0005737; GO:0005886; GO:0005925; GO:0006816; GO:0006937; GO:0008201; GO:0015276; GO:0015485; GO:0016020; GO:0019899; GO:0030061; GO:0031214; GO:0031982; GO:0035374; GO:0038024; GO:0042470; GO:0042584; GO:0048306; GO:0048471; GO:0051015; GO:0051283; GO:0051560; GO:0070509; GO:0070588; GO:0097190 20990 XM_029329774.2 0 143 0 0 18 P79134 2.37e-59 Annexin A6 (Annexin VI) (Annexin-6) Bos taurus (Bovine) apoptotic signaling pathway [GO:0097190]; biomineral tissue development [GO:0031214]; calcium ion import [GO:0070509]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; growth plate cartilage chondrocyte differentiation [GO:0003418]; mitochondrial calcium ion homeostasis [GO:0051560]; negative regulation of sequestering of calcium ion [GO:0051283]; neural crest cell migration [GO:0001755]; plasma membrane repair [GO:0001778]; regulation of muscle contraction [GO:0006937] GO:0001725; GO:0001755; GO:0001778; GO:0001786; GO:0003418; GO:0005262; GO:0005509; GO:0005525; GO:0005544; GO:0005737; GO:0005886; GO:0005925; GO:0006816; GO:0006937; GO:0008201; GO:0015276; GO:0015485; GO:0016020; GO:0019899; GO:0030061; GO:0031214; GO:0031982; GO:0035374; GO:0038024; GO:0042470; GO:0042584; GO:0048306; GO:0048471; GO:0051015; GO:0051283; GO:0051560; GO:0070509; GO:0070588; GO:0097190 20991 XM_029329774.2 0 143 0 0 18 P79134 3.11e-38 Annexin A6 (Annexin VI) (Annexin-6) Bos taurus (Bovine) apoptotic signaling pathway [GO:0097190]; biomineral tissue development [GO:0031214]; calcium ion import [GO:0070509]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; growth plate cartilage chondrocyte differentiation [GO:0003418]; mitochondrial calcium ion homeostasis [GO:0051560]; negative regulation of sequestering of calcium ion [GO:0051283]; neural crest cell migration [GO:0001755]; plasma membrane repair [GO:0001778]; regulation of muscle contraction [GO:0006937] GO:0001725; GO:0001755; GO:0001778; GO:0001786; GO:0003418; GO:0005262; GO:0005509; GO:0005525; GO:0005544; GO:0005737; GO:0005886; GO:0005925; GO:0006816; GO:0006937; GO:0008201; GO:0015276; GO:0015485; GO:0016020; GO:0019899; GO:0030061; GO:0031214; GO:0031982; GO:0035374; GO:0038024; GO:0042470; GO:0042584; GO:0048306; GO:0048471; GO:0051015; GO:0051283; GO:0051560; GO:0070509; GO:0070588; GO:0097190 20992 XM_029329774.2 0 143 0 0 18 P79134 1.82e-34 Annexin A6 (Annexin VI) (Annexin-6) Bos taurus (Bovine) apoptotic signaling pathway [GO:0097190]; biomineral tissue development [GO:0031214]; calcium ion import [GO:0070509]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; growth plate cartilage chondrocyte differentiation [GO:0003418]; mitochondrial calcium ion homeostasis [GO:0051560]; negative regulation of sequestering of calcium ion [GO:0051283]; neural crest cell migration [GO:0001755]; plasma membrane repair [GO:0001778]; regulation of muscle contraction [GO:0006937] GO:0001725; GO:0001755; GO:0001778; GO:0001786; GO:0003418; GO:0005262; GO:0005509; GO:0005525; GO:0005544; GO:0005737; GO:0005886; GO:0005925; GO:0006816; GO:0006937; GO:0008201; GO:0015276; GO:0015485; GO:0016020; GO:0019899; GO:0030061; GO:0031214; GO:0031982; GO:0035374; GO:0038024; GO:0042470; GO:0042584; GO:0048306; GO:0048471; GO:0051015; GO:0051283; GO:0051560; GO:0070509; GO:0070588; GO:0097190 20993 XM_029350437.2 1180 982 563 856 679 Q6UL01 1.96e-23 MORN repeat-containing protein 2 (MORN motif protein in testis) Mus musculus (Mouse) cell differentiation [GO:0030154]; spermatogenesis [GO:0007283] GO:0001669; GO:0005634; GO:0007283; GO:0030154 20994 XM_044309888.1 15 7 30 94 113 NA NA NA NA NA NA 20995 XM_044308660.1 188 0 8 157 0 NA NA NA NA NA NA 20996 XR_003827078.2 17 7 7 1 13 NA NA NA NA NA NA 20997 XM_029342231.2 141 29 53 11 45 Q8R4F0 2.4e-121 Mucolipin-3 (Transient receptor potential channel mucolipin 3) (TRPML3) Mus musculus (Mouse) inner ear auditory receptor cell differentiation [GO:0042491]; locomotory behavior [GO:0007626] GO:0000421; GO:0005737; GO:0005765; GO:0005886; GO:0007626; GO:0008289; GO:0016020; GO:0031901; GO:0031902; GO:0042491; GO:0060171; GO:0072345 20998 XM_029327683.2 3 23 0 2 11 NA NA NA NA NA NA 20999 XM_044323454.1 642 61 3 11 73 NA NA NA NA NA NA 21000 XM_029341600.2 0 0 0 0 656 Q6P2Y1 2.22e-104 RNA polymerase II-associated factor 1 homolog Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) histone modification [GO:0016570]; negative regulation of transcription by RNA polymerase II [GO:0000122]; transcription elongation by RNA polymerase II promoter [GO:0006368] GO:0000122; GO:0000993; GO:0006368; GO:0016570; GO:0016593 21001 XM_029341600.2 0 0 0 0 656 Q6P2Y1 2.22e-104 RNA polymerase II-associated factor 1 homolog Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) histone modification [GO:0016570]; negative regulation of transcription by RNA polymerase II [GO:0000122]; transcription elongation by RNA polymerase II promoter [GO:0006368] GO:0000122; GO:0000993; GO:0006368; GO:0016570; GO:0016593 21002 XR_006394471.1 2589 4613 3412 3720 4955 NA NA NA NA NA NA 21003 XM_029338135.2 0 0 7 25 10 NA NA NA NA NA NA 21004 XM_044313132.1 36 120 42 30 54 NA NA NA NA NA NA 21005 XR_003826748.2 0 0 5 0 7 NA NA NA NA NA NA 21006 XM_044307348.1 1471 1907 863 1181 1514 Q6PB93 0 Polypeptide N-acetylgalactosaminyltransferase 2 (EC 2.4.1.41) (Polypeptide GalNAc transferase 2) (GalNAc-T2) (pp-GaNTase 2) (Protein-UDP acetylgalactosaminyltransferase 2) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 2) [Cleaved into: Polypeptide N-acetylgalactosaminyltransferase 2 soluble form] Mus musculus (Mouse) O-glycan processing [GO:0016266]; protein maturation [GO:0051604]; protein O-linked glycosylation [GO:0006493]; protein O-linked glycosylation via serine [GO:0018242]; protein O-linked glycosylation via threonine [GO:0018243] GO:0004653; GO:0005576; GO:0005794; GO:0005795; GO:0005796; GO:0006493; GO:0016266; GO:0018242; GO:0018243; GO:0030145; GO:0030246; GO:0032580; GO:0048471; GO:0051604 21007 XM_044307608.1 0 0 0 0 69 E0W1I1 4.06e-75 Serine/threonine-protein kinase Pink1, mitochondrial (EC 2.7.11.1) (PTEN-induced putative kinase 1) Pediculus humanus subsp. corporis (Body louse) autophagy [GO:0006914]; protein phosphorylation [GO:0006468] GO:0004672; GO:0004674; GO:0005524; GO:0005741; GO:0005743; GO:0005829; GO:0006468; GO:0006914; GO:0046872 21008 XM_044319317.1 0 9 11 0 8 Q8WPA2 4.81e-29 Allatostatin-A receptor (BAR) Bombyx mori (Silk moth) NA GO:0004930; GO:0005886; GO:0042562; GO:0042923 21009 XR_003823804.2 180 213 22 183 172 NA NA NA NA NA NA 21010 XM_044322701.1 324 307 261 366 524 Q9Y5Z4 8.87e-24 Heme-binding protein 2 (Placental protein 23) (PP23) (Protein SOUL) Homo sapiens (Human) negative regulation of mitochondrial membrane potential [GO:0010917]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of necrotic cell death [GO:0010940] GO:0005576; GO:0005737; GO:0005739; GO:0010917; GO:0010940; GO:0020037; GO:0035578; GO:0035794; GO:0070062 21011 XM_044311363.1 41 19 65 37 18 NA NA NA NA NA NA 21012 XM_044324894.1 2 7 10 15 13 NA NA NA NA NA NA 21013 XM_044322969.1 458 429 397 580 790 Q8N1F8 5.57e-47 Serine/threonine-protein kinase 11-interacting protein (LKB1-interacting protein 1) Homo sapiens (Human) protein localization [GO:0008104] GO:0005576; GO:0005737; GO:0005765; GO:0008104; GO:0019901; GO:0035578; GO:0043231 21014 XM_044318527.1 1874 1327 1022 3961 2605 Q9U3S9 5.41e-49 Zinc metalloproteinase nas-6 (EC 3.4.24.-) (Nematode astacin 6) Caenorhabditis elegans pharyngeal pumping [GO:0043050]; pharynx development [GO:0060465]; proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0006508; GO:0008270; GO:0043050; GO:0060465 21015 XM_044308705.1 85 201 142 70 135 NA NA NA NA NA NA 21016 XM_044318699.1 32 0 29 0 43 NA NA NA NA NA NA 21017 XM_044320520.1 2648 1941 2217 3758 2162 P55115 1.08e-36 Zinc metalloproteinase nas-15 (EC 3.4.24.-) (Nematode astacin 15) Caenorhabditis elegans proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0006508; GO:0008270 21018 XR_006397112.1 126 126 103 171 194 NA NA NA NA NA NA 21019 XM_029340596.2 750 532 202 1332 220 NA NA NA NA NA NA 21020 XM_044319752.1 0 0 0 12 0 A5D9C6 1.69e-79 Repressor of RNA polymerase III transcription MAF1 homolog Bos taurus (Bovine) negative regulation of transcription by RNA polymerase III [GO:0016480] GO:0000994; GO:0005634; GO:0005737; GO:0016480 21021 XM_029348546.2 102 0 89 0 110 Q5ZLN0 5.4e-149 Leucine-rich repeat-containing protein 40 Gallus gallus (Chicken) cardiac muscle cell development [GO:0055013] GO:0003779; GO:0005856; GO:0030017; GO:0055013 21022 XM_029348546.2 102 0 89 0 110 Q5ZLN0 1.9e-24 Leucine-rich repeat-containing protein 40 Gallus gallus (Chicken) cardiac muscle cell development [GO:0055013] GO:0003779; GO:0005856; GO:0030017; GO:0055013 21023 XM_029336992.2 830 867 858 897 1551 Q6PAY6 1.27e-84 Hydroxyproline dehydrogenase (HYPDH) (EC 1.5.5.3) (Probable proline dehydrogenase 2) (EC 1.5.5.2) (Probable proline oxidase 2) Xenopus laevis (African clawed frog) proline catabolic process to glutamate [GO:0010133] GO:0004657; GO:0010133; GO:0016645 21024 XM_029334826.2 837 341 344 694 709 Q98931 6.37e-126 Low-density lipoprotein receptor-related protein 8 (LRP-8) (Apolipoprotein E receptor 2) (Protein LR8B) Gallus gallus (Chicken) endocytosis [GO:0006897]; ventral spinal cord development [GO:0021517] GO:0005509; GO:0006897; GO:0016020; GO:0021517 21025 XM_029334177.2 0 0 15 0 0 NA NA NA NA NA NA 21026 XM_029351909.2 161 250 85 288 194 Q9WTV5 8.62e-60 26S proteasome non-ATPase regulatory subunit 9 (26S proteasome regulatory subunit p27) (Transactivating protein Bridge-1) Rattus norvegicus (Rat) negative regulation of insulin secretion [GO:0046676]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteasome regulatory particle assembly [GO:0070682]; proteolysis [GO:0006508]; type B pancreatic cell apoptotic process [GO:0097050] GO:0003713; GO:0004222; GO:0005634; GO:0005737; GO:0006508; GO:0008022; GO:0032024; GO:0043425; GO:0045893; GO:0045944; GO:0046676; GO:0070682; GO:0097050 21027 XM_029349803.2 803 698 406 959 750 NA NA NA NA NA NA 21028 XM_044329202.1 57 61 152 52 268 NA NA NA NA NA NA 21029 XM_044325110.1 0 0 4 0 19 NA NA NA NA NA NA 21030 XM_029337752.2 1078 734 503 659 442 NA NA NA NA NA NA 21031 XM_029335763.2 0 206 0 63 302 Q9Y251 1.42e-102 Heparanase (EC 3.2.1.166) (Endo-glucoronidase) (Heparanase-1) (Hpa1) [Cleaved into: Heparanase 8 kDa subunit; Heparanase 50 kDa subunit] Homo sapiens (Human) angiogenesis involved in wound healing [GO:0060055]; cell-matrix adhesion [GO:0007160]; establishment of endothelial barrier [GO:0061028]; Factor XII activation [GO:0002542]; heparan sulfate proteoglycan catabolic process [GO:0030200]; heparin metabolic process [GO:0030202]; inflammatory response [GO:0006954]; positive regulation of angiogenesis [GO:0045766]; positive regulation of autophagy [GO:0010508]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of hair follicle development [GO:0051798]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vascular endothelial growth factor production [GO:0010575]; protein transmembrane transport [GO:0071806]; proteoglycan metabolic process [GO:0006029]; regulation of hair follicle development [GO:0051797]; response to organic substance [GO:0010033]; vascular wound healing [GO:0061042] GO:0001954; GO:0002542; GO:0004566; GO:0005576; GO:0005615; GO:0005634; GO:0005654; GO:0005764; GO:0005765; GO:0005768; GO:0005776; GO:0006029; GO:0006954; GO:0007160; GO:0008284; GO:0010033; GO:0010508; GO:0010575; GO:0030194; GO:0030200; GO:0030202; GO:0030305; GO:0030335; GO:0031012; GO:0033690; GO:0035580; GO:0043202; GO:0043231; GO:0045121; GO:0045545; GO:0045766; GO:0051797; GO:0051798; GO:0051897; GO:0060055; GO:0061028; GO:0061042; GO:0071806; GO:0090091; GO:1900026; GO:1904974 21032 XM_044320412.1 0 122 0 54 481 NA NA NA NA NA NA 21033 XM_044322827.1 498 320 324 399 497 NA NA NA NA NA NA 21034 XM_044318768.1 18 48 195 112 4 NA NA NA NA NA NA 21035 XR_006397218.1 23 0 0 0 39 NA NA NA NA NA NA 21036 XM_029340723.2 0 0 0 2 134 Q3UZD5 1.59e-35 Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.361) (PR domain zinc finger protein 6) (PR domain-containing protein 6) (PR domain-containing protein in smooth muscle) Mus musculus (Mouse) chromatin organization [GO:0006325]; histone methylation [GO:0016571]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of smooth muscle cell differentiation [GO:0051151]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of gene expression [GO:0010468] GO:0000122; GO:0005634; GO:0006325; GO:0010468; GO:0016571; GO:0022008; GO:0042802; GO:0045892; GO:0046872; GO:0051151; GO:0140944 21037 XM_044307359.1 69 26 11 5 50 NA NA NA NA NA NA 21038 XR_006396927.1 144 100 32 82 62 NA NA NA NA NA NA 21039 XM_044323893.1 93 49 401 831 187 NA NA NA NA NA NA 21040 XM_029341036.2 1292 1055 788 1288 1068 P07090 6.78e-50 Calretinin (CR) Gallus gallus (Chicken) regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of long-term synaptic potentiation [GO:1900271]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509] GO:0005509; GO:0005634; GO:0005829; GO:0030425; GO:0043005; GO:0043195; GO:0045202; GO:0051480; GO:0099509; GO:1900271 21041 XM_044311469.1 10 22 7 0 12 Q15485 2.04e-79 Ficolin-2 (37 kDa elastin-binding protein) (Collagen/fibrinogen domain-containing protein 2) (EBP-37) (Ficolin-B) (Ficolin-beta) (Hucolin) (L-ficolin) (Serum lectin p35) Homo sapiens (Human) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; positive regulation of opsonization [GO:1903028]; proteolysis [GO:0006508]; recognition of apoptotic cell [GO:0043654] GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005576; GO:0005581; GO:0005615; GO:0006508; GO:0008228; GO:0009897; GO:0042802; GO:0043394; GO:0043654; GO:0046872; GO:0048306; GO:0050829; GO:0050830; GO:0062023; GO:0070062; GO:0072562; GO:0097367; GO:1903028; GO:1905370; GO:2001065 21042 XM_029328593.2 82 63 32 101 140 F6TQD1 6.18e-24 Probable E3 SUMO-protein ligase RNF212 (EC 2.3.2.-) (Probable E3 SUMO-protein transferase RNF212) (RING finger protein 212) Mus musculus (Mouse) chiasma assembly [GO:0051026]; homologous chromosome pairing at meiosis [GO:0007129]; meiotic gene conversion [GO:0006311]; protein sumoylation [GO:0016925]; reciprocal meiotic recombination [GO:0007131] GO:0000795; GO:0006311; GO:0007129; GO:0007131; GO:0016925; GO:0019789; GO:0046872; GO:0051026 21043 XM_044326036.1 671 552 425 966 787 O35491 1.97e-162 Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2) Mus musculus (Mouse) negative regulation of gluconeogenesis [GO:0045721]; peptidyl-tyrosine phosphorylation [GO:0018108]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of RNA splicing [GO:0043484]; response to ionizing radiation [GO:0010212]; response to organic substance [GO:0010033]; response to retinoic acid [GO:0032526] GO:0004674; GO:0004712; GO:0004713; GO:0005524; GO:0005634; GO:0005654; GO:0006468; GO:0010033; GO:0010212; GO:0016604; GO:0016607; GO:0018108; GO:0032526; GO:0042802; GO:0043484; GO:0045721; GO:0046777; GO:0106310 21044 XM_044322406.1 14 256 20 3 18 NA NA NA NA NA NA 21045 XR_003823461.2 7 4 2 0 17 NA NA NA NA NA NA 21046 XR_006395154.1 177 209 170 306 176 NA NA NA NA NA NA 21047 XM_044321587.1 196 198 107 62 0 NA NA NA NA NA NA 21048 XM_044315352.1 19 3 3 189 30 NA NA NA NA NA NA 21049 XM_029344472.2 18 22 30 36 0 P50238 2.15e-23 Cysteine-rich protein 1 (CRP-1) (Cysteine-rich heart protein) (CRHP) (hCRHP) (Cysteine-rich intestinal protein) (CRIP) Homo sapiens (Human) cellular response to antibiotic [GO:0071236]; cellular response to UV-B [GO:0071493]; heart development [GO:0007507]; immune response [GO:0006955]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; prostate gland stromal morphogenesis [GO:0060741]; regulation of gene expression [GO:0010468]; response to organic substance [GO:0010033]; response to zinc ion [GO:0010043] GO:0005737; GO:0006955; GO:0007507; GO:0008270; GO:0008630; GO:0010033; GO:0010043; GO:0010468; GO:0042277; GO:0060741; GO:0071236; GO:0071493 21050 XM_029356600.2 0 0 5 0 18 NA NA NA NA NA NA 21051 XM_029336946.2 30 7 16 19 49 Q94887 2.08e-37 Neurexin-4 (Neurexin IV) Drosophila melanogaster (Fruit fly) axon ensheathment [GO:0008366]; cell adhesion involved in heart morphogenesis [GO:0061343]; cell-cell junction organization [GO:0045216]; dorsal closure [GO:0007391]; establishment of glial blood-brain barrier [GO:0060857]; heart process [GO:0003015]; nerve maturation [GO:0021682]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]; synaptic target recognition [GO:0008039]; terminal button organization [GO:0072553] GO:0003015; GO:0005886; GO:0005919; GO:0007391; GO:0008039; GO:0008104; GO:0008366; GO:0019991; GO:0021682; GO:0035151; GO:0045202; GO:0045216; GO:0048786; GO:0060857; GO:0061343; GO:0072553; GO:0097105 21052 XM_044323212.1 26 2 0 7 94 NA NA NA NA NA NA 21053 XM_044308624.1 0 4 11 20 12 NA NA NA NA NA NA 21054 XM_029345463.2 345 0 115 304 98 Q8N2E2 1.43e-39 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 21055 XM_029345463.2 345 0 115 304 98 Q8N2E2 8.72e-38 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 21056 XM_029345463.2 345 0 115 304 98 Q8N2E2 1.55e-36 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 21057 XM_029345463.2 345 0 115 304 98 Q8N2E2 4.87e-35 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 21058 XM_029345463.2 345 0 115 304 98 Q8N2E2 5.76e-32 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 21059 XM_029345463.2 345 0 115 304 98 Q8N2E2 4.24e-25 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 21060 XR_006393720.1 19 0 0 0 0 NA NA NA NA NA NA 21061 XM_044316118.1 37 11 7 1 12 NA NA NA NA NA NA 21062 XM_044320212.1 1153 880 519 547 381 NA NA NA NA NA NA 21063 XM_044311659.1 6 6 1 3 10 B8VIU6 6.18e-71 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 21064 XM_044309952.1 342 64 232 505 214 Q7SIC1 1.14e-21 Fucolectin Anguilla anguilla (European freshwater eel) (Muraena anguilla) regulation of cellular defense response [GO:0010185]; regulation of complement activation, lectin pathway [GO:0001868]; regulation of innate immune response [GO:0045088] GO:0001868; GO:0005509; GO:0005576; GO:0010185; GO:0030246; GO:0042806; GO:0045088 21065 XM_029351411.2 1788 1996 788 2773 1199 Q9PRL8 6.79e-33 Acyl-CoA-binding protein (ACBP) (Diazepam-binding inhibitor) (DBI) Gallus gallus (Chicken) fatty acid metabolic process [GO:0006631] GO:0000062; GO:0005783; GO:0005794; GO:0006631 21066 XM_029340753.2 1407 1356 1212 2471 1633 Q9FHN8 7.11e-122 Kinesin-like protein KIN-14E (Kinesin-like calmodulin-binding protein) (Protein ZWICHEL) Arabidopsis thaliana (Mouse-ear cress) cortical microtubule organization [GO:0043622]; microtubule bundle formation [GO:0001578]; microtubule-based movement [GO:0007018]; trichome branching [GO:0010091]; trichome patterning [GO:0048629] GO:0001578; GO:0003777; GO:0005509; GO:0005516; GO:0005524; GO:0005856; GO:0005871; GO:0005874; GO:0007018; GO:0008017; GO:0008569; GO:0009524; GO:0010091; GO:0016491; GO:0016887; GO:0019901; GO:0042803; GO:0043531; GO:0043622; GO:0048629; GO:0051015; GO:0055028; GO:0072686 21067 XM_029341438.2 265 348 294 245 345 NA NA NA NA NA NA 21068 XM_044316973.1 71 34 43 77 25 Q5R4J5 1.74e-44 Synaptotagmin-1 (Synaptotagmin I) (SytI) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cell differentiation [GO:0030154]; positive regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903235] GO:0030154; GO:0030672; GO:0042584; GO:0046872; GO:1903235 21069 XM_029353775.2 2420 1528 1012 1345 1308 Q5FWL3 7.37e-141 E3 ubiquitin-protein ligase NRDP1 (EC 2.3.2.27) (RING finger protein 41) (RING-type E3 ubiquitin transferase NRDP1) Xenopus laevis (African clawed frog) extrinsic apoptotic signaling pathway [GO:0097191]; protein polyubiquitination [GO:0000209] GO:0000209; GO:0004842; GO:0046872; GO:0061630; GO:0097191 21070 XM_044310926.1 101 493 274 217 242 NA NA NA NA NA NA 21071 XR_006394253.1 11 4 43 9 189 NA NA NA NA NA NA 21072 XM_044320869.1 8 5 7 23 13 O14830 2.06e-46 Serine/threonine-protein phosphatase with EF-hands 2 (PPEF-2) (EC 3.1.3.16) Homo sapiens (Human) detection of stimulus involved in sensory perception [GO:0050906]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; protein dephosphorylation [GO:0006470]; regulation of JUN kinase activity [GO:0043506]; regulation of MAP kinase activity [GO:0043405]; visual perception [GO:0007601] GO:0001750; GO:0001917; GO:0004722; GO:0005506; GO:0005509; GO:0005634; GO:0005829; GO:0006470; GO:0007601; GO:0010801; GO:0017018; GO:0030145; GO:0030544; GO:0031435; GO:0043405; GO:0043409; GO:0043506; GO:0050906; GO:0051879 21073 XM_044320783.1 11 4 13 16 42 NA NA NA NA NA NA 21074 XM_029344754.2 0 0 119 254 254 Q09225 1.71e-45 Nose resistant to fluoxetine protein 6 (Protein nrf-6) Caenorhabditis elegans lipid transport [GO:0006869] GO:0006869; GO:0008289; GO:0016020; GO:0016747 21075 XM_029341933.2 1268 642 634 740 981 P25490 8.12e-111 Transcriptional repressor protein YY1 (Delta transcription factor) (INO80 complex subunit S) (NF-E1) (Yin and yang 1) (YY-1) Homo sapiens (Human) anterior/posterior pattern specification [GO:0009952]; B cell differentiation [GO:0030183]; camera-type eye morphogenesis [GO:0048593]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to interleukin-1 [GO:0071347]; cellular response to UV [GO:0034644]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; negative regulation of cell growth involved in cardiac muscle cell development [GO:0061052]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of miRNA transcription [GO:1902894]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of telomere maintenance in response to DNA damage [GO:1904507]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell cycle [GO:0051726]; regulation of chromosome organization [GO:0033044]; regulation of DNA repair [GO:0006282]; regulation of DNA replication [GO:0006275]; regulation of DNA strand elongation [GO:0060382]; regulation of embryonic development [GO:0045995]; regulation of transcription by RNA polymerase II [GO:0006357]; response to prostaglandin F [GO:0034696]; response to UV-C [GO:0010225]; RNA localization [GO:0006403]; spermatogenesis [GO:0007283]; telomere maintenance [GO:0000723] GO:0000122; GO:0000400; GO:0000723; GO:0000724; GO:0000976; GO:0000978; GO:0000981; GO:0000987; GO:0001217; GO:0001227; GO:0001228; GO:0003677; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005667; GO:0005677; GO:0005737; GO:0006275; GO:0006282; GO:0006338; GO:0006357; GO:0006403; GO:0006974; GO:0007283; GO:0009952; GO:0010225; GO:0010628; GO:0010629; GO:0016363; GO:0030183; GO:0031011; GO:0031519; GO:0032688; GO:0033044; GO:0034644; GO:0034696; GO:0045739; GO:0045893; GO:0045944; GO:0045995; GO:0046332; GO:0046872; GO:0048593; GO:0051726; GO:0060382; GO:0061052; GO:0071347; GO:0071707; GO:0140297; GO:1902894; GO:1904507; GO:1990837 21076 XM_029350290.2 52 113 37 0 83 Q6L8F3 1.59e-32 NA NA NA NA 21077 XM_029346345.2 0 0 0 114 5 B3EWY6 0 Skeletal aspartic acid-rich protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 21078 XM_029337400.2 395 275 61 649 1124 Q06441 3.05e-175 Thrombospondin-4 Xenopus laevis (African clawed frog) cell adhesion [GO:0007155]; positive regulation of cell division [GO:0051781]; response to unfolded protein [GO:0006986] GO:0005509; GO:0005615; GO:0005783; GO:0006986; GO:0007155; GO:0008083; GO:0016529; GO:0051781; GO:0062023 21079 XM_029332487.2 1615 270 0 286 534 Q4R562 1.65e-153 Beta-arrestin-1 (Arrestin beta-1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) negative regulation of Notch signaling pathway [GO:0045746]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; protein transport [GO:0015031]; signal transduction [GO:0007165]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0001934; GO:0002092; GO:0005634; GO:0005905; GO:0006511; GO:0007165; GO:0015031; GO:0031143; GO:0031410; GO:0045746 21080 XM_044310329.1 0 26 0 36 20 NA NA NA NA NA NA 21081 XM_029336197.2 20 0 10 7 21 NA NA NA NA NA NA 21082 XR_006394576.1 0 68 0 47 40 NA NA NA NA NA NA 21083 XR_003824375.2 41 19 5 16 26 NA NA NA NA NA NA 21084 XM_029337894.2 610 421 368 618 701 P30419 0 Glycylpeptide N-tetradecanoyltransferase 1 (EC 2.3.1.97) (Myristoyl-CoA:protein N-myristoyltransferase 1) (HsNMT1) (NMT 1) (Type I N-myristoyltransferase) (Peptide N-myristoyltransferase 1) (Protein-lysine myristoyltransferase NMT1) (EC 2.3.1.-) Homo sapiens (Human) cellular ketone metabolic process [GO:0042180]; in utero embryonic development [GO:0001701]; N-terminal peptidyl-glycine N-myristoylation [GO:0018008]; N-terminal protein myristoylation [GO:0006499]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; regulation of rhodopsin mediated signaling pathway [GO:0022400] GO:0001701; GO:0004379; GO:0005737; GO:0005739; GO:0005829; GO:0005886; GO:0006499; GO:0018008; GO:0018030; GO:0019107; GO:0019898; GO:0022400; GO:0042180; GO:1900740 21085 XR_006395961.1 60 48 13 63 40 Q99570 0 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 21086 XR_006395961.1 60 48 13 63 40 Q99570 0 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 21087 XM_029348119.2 35 89 68 187 72 Q708S4 4.53e-55 Acid-sensing ion channel 4-A (ASIC4-A) (Acid-sensing ion channel 4.1) (Amiloride-sensitive cation channel 4-A) (ZASIC4.1) Danio rerio (Zebrafish) (Brachydanio rerio) sodium ion transmembrane transport [GO:0035725] GO:0005248; GO:0005261; GO:0005886; GO:0015280; GO:0035725; GO:0045177 21088 XM_044329117.1 0 9 12 0 9 NA NA NA NA NA NA 21089 XM_044328527.1 822 622 402 808 517 Q6L8S8 4.02e-57 Beta-1,4-N-acetylgalactosaminyltransferase 3 (Beta4GalNAc-T3) (Beta4GalNAcT3) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase III) (N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 2) (NGalNAc-T2) Mus musculus (Mouse) chondroitin sulfate biosynthetic process [GO:0030206] GO:0005794; GO:0008376; GO:0030206; GO:0032580; GO:0033842; GO:0043231; GO:0047238 21090 XM_044324710.1 17 9 12 16 15 NA NA NA NA NA NA 21091 XR_006397875.1 6 268 3 0 406 NA NA NA NA NA NA 21092 XR_006393895.1 41 2 25 5 151 NA NA NA NA NA NA 21093 XM_029337986.2 2048 1576 1062 1484 1226 E2RQ08 0 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (Ribophorin I) (RPN-I) (Ribophorin-1) Canis lupus familiaris (Dog) (Canis familiaris) protein glycosylation [GO:0006486]; protein N-linked glycosylation via asparagine [GO:0018279] GO:0005791; GO:0005829; GO:0006486; GO:0008250; GO:0018279 21094 XR_006391278.1 1603 1571 969 1728 1324 Q2XVR4 1.99e-138 Sodium channel protein type 4 subunit alpha B (Voltage-gated sodium channel subunit alpha Nav1.4b) Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon nigroviridis) regulation of ion transmembrane transport [GO:0034765] GO:0001518; GO:0005244; GO:0005248; GO:0034765 21095 XR_006391278.1 1603 1571 969 1728 1324 Q2XVR4 8.81e-130 Sodium channel protein type 4 subunit alpha B (Voltage-gated sodium channel subunit alpha Nav1.4b) Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon nigroviridis) regulation of ion transmembrane transport [GO:0034765] GO:0001518; GO:0005244; GO:0005248; GO:0034765 21096 XR_006391278.1 1603 1571 969 1728 1324 Q2XVR4 8.81e-130 Sodium channel protein type 4 subunit alpha B (Voltage-gated sodium channel subunit alpha Nav1.4b) Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon nigroviridis) regulation of ion transmembrane transport [GO:0034765] GO:0001518; GO:0005244; GO:0005248; GO:0034765 21097 XR_006391278.1 1603 1571 969 1728 1324 Q2XVR4 8.81e-130 Sodium channel protein type 4 subunit alpha B (Voltage-gated sodium channel subunit alpha Nav1.4b) Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon nigroviridis) regulation of ion transmembrane transport [GO:0034765] GO:0001518; GO:0005244; GO:0005248; GO:0034765 21098 XR_006391278.1 1603 1571 969 1728 1324 Q2XVR4 8.81e-130 Sodium channel protein type 4 subunit alpha B (Voltage-gated sodium channel subunit alpha Nav1.4b) Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon nigroviridis) regulation of ion transmembrane transport [GO:0034765] GO:0001518; GO:0005244; GO:0005248; GO:0034765 21099 XR_006391278.1 1603 1571 969 1728 1324 Q2XVR4 8.81e-130 Sodium channel protein type 4 subunit alpha B (Voltage-gated sodium channel subunit alpha Nav1.4b) Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon nigroviridis) regulation of ion transmembrane transport [GO:0034765] GO:0001518; GO:0005244; GO:0005248; GO:0034765 21100 XM_044316094.1 6 4 4 15 10 NA NA NA NA NA NA 21101 XM_029330173.2 0 123 0 19 156 A4UTP7 2.84e-63 Myocyte-specific enhancer factor 2C Sus scrofa (Pig) B cell homeostasis [GO:0001782]; B cell proliferation [GO:0042100]; B cell receptor signaling pathway [GO:0050853]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cardiac ventricle formation [GO:0003211]; cardiocyte differentiation [GO:0035051]; cellular response to calcium ion [GO:0071277]; cellular response to fluid shear stress [GO:0071498]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cellular response to trichostatin A [GO:0035984]; cellular response to xenobiotic stimulus [GO:0071466]; chondrocyte differentiation [GO:0002062]; endochondral ossification [GO:0001958]; epithelial cell proliferation involved in renal tubule morphogenesis [GO:2001013]; germinal center formation [GO:0002467]; glomerulus morphogenesis [GO:0072102]; heart development [GO:0007507]; heart looping [GO:0001947]; humoral immune response [GO:0006959]; learning or memory [GO:0007611]; MAPK cascade [GO:0000165]; melanocyte differentiation [GO:0030318]; muscle cell fate determination [GO:0007521]; negative regulation of gene expression [GO:0010629]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of ossification [GO:0030279]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nephron tubule epithelial cell differentiation [GO:0072160]; neural crest cell differentiation [GO:0014033]; neuron development [GO:0048666]; neuron differentiation [GO:0030182]; osteoblast differentiation [GO:0001649]; outflow tract morphogenesis [GO:0003151]; platelet formation [GO:0030220]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of behavioral fear response [GO:2000987]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cardiac muscle cell differentiation [GO:2000727]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of macrophage apoptotic process [GO:2000111]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of skeletal muscle cell differentiation [GO:2001016]; positive regulation of skeletal muscle tissue development [GO:0048643]; positive regulation of transcription by RNA polymerase II [GO:0045944]; primary heart field specification [GO:0003138]; regulation of germinal center formation [GO:0002634]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of synaptic activity [GO:0060025]; regulation of transcription by RNA polymerase II [GO:0006357]; renal tubule morphogenesis [GO:0061333]; secondary heart field specification [GO:0003139]; sinoatrial valve morphogenesis [GO:0003185]; skeletal muscle tissue development [GO:0007519]; smooth muscle cell differentiation [GO:0051145]; ventricular cardiac muscle cell differentiation [GO:0055012] GO:0000122; GO:0000165; GO:0000976; GO:0000977; GO:0000978; GO:0000981; GO:0001228; GO:0001568; GO:0001649; GO:0001782; GO:0001947; GO:0001958; GO:0001974; GO:0002062; GO:0002467; GO:0002634; GO:0003138; GO:0003139; GO:0003151; GO:0003185; GO:0003211; GO:0003677; GO:0003700; GO:0005634; GO:0005737; GO:0006357; GO:0006959; GO:0007507; GO:0007519; GO:0007521; GO:0007611; GO:0010628; GO:0010629; GO:0010694; GO:0014033; GO:0016528; GO:0016607; GO:0030182; GO:0030220; GO:0030279; GO:0030318; GO:0030501; GO:0030890; GO:0032991; GO:0035051; GO:0035984; GO:0042100; GO:0043524; GO:0045652; GO:0045663; GO:0045666; GO:0045669; GO:0045893; GO:0045944; GO:0046983; GO:0048643; GO:0048666; GO:0050853; GO:0051145; GO:0055012; GO:0060025; GO:0060045; GO:0061333; GO:0071222; GO:0071277; GO:0071374; GO:0071466; GO:0071498; GO:0071560; GO:0072102; GO:0072160; GO:2000111; GO:2000727; GO:2000987; GO:2001013; GO:2001016 21102 XM_029338688.2 118 4 319 349 451 Q02447 1.98e-40 Transcription factor Sp3 (SPR-2) Homo sapiens (Human) B cell differentiation [GO:0030183]; definitive hemopoiesis [GO:0060216]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic placenta development [GO:0001892]; embryonic process involved in female pregnancy [GO:0060136]; embryonic skeletal system development [GO:0048706]; enucleate erythrocyte differentiation [GO:0043353]; granulocyte differentiation [GO:0030851]; liver development [GO:0001889]; lung development [GO:0030324]; megakaryocyte differentiation [GO:0030219]; monocyte differentiation [GO:0030224]; myeloid progenitor cell differentiation [GO:0002318]; natural killer cell differentiation [GO:0001779]; negative regulation of DNA-templated transcription [GO:0045892]; ossification [GO:0001503]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; T cell differentiation [GO:0030217]; trophectodermal cell differentiation [GO:0001829] GO:0000785; GO:0000977; GO:0000978; GO:0000981; GO:0001227; GO:0001503; GO:0001779; GO:0001829; GO:0001889; GO:0001892; GO:0002318; GO:0003682; GO:0005634; GO:0005654; GO:0005829; GO:0006355; GO:0006357; GO:0016605; GO:0017053; GO:0030183; GO:0030217; GO:0030219; GO:0030224; GO:0030324; GO:0030851; GO:0032993; GO:0043353; GO:0045892; GO:0045893; GO:0045944; GO:0046872; GO:0048596; GO:0048706; GO:0060136; GO:0060216; GO:0061629; GO:1990837 21103 XM_044308467.1 44855 41419 23589 38003 21300 P16580 0 Glutamine synthetase (GS) (EC 6.3.1.2) (Glutamate decarboxylase) (EC 4.1.1.15) (Glutamate--ammonia ligase) (p42) Gallus gallus (Chicken) glutamine biosynthetic process [GO:0006542] GO:0004351; GO:0004356; GO:0005524; GO:0005737; GO:0005739; GO:0006542; GO:0046872 21104 XR_006394271.1 11 4 43 9 189 NA NA NA NA NA NA 21105 XR_006397909.1 8 1 13 7 15 NA NA NA NA NA NA 21106 XM_044314272.1 1 0 12 0 7 NA NA NA NA NA NA 21107 XM_029327859.2 47 22 6 0 33 NA NA NA NA NA NA 21108 XR_003823598.2 518 405 333 280 243 NA NA NA NA NA NA 21109 XM_044325168.1 107 56 0 131 54 NA NA NA NA NA NA 21110 XM_029337881.2 27 0 11 0 0 NA NA NA NA NA NA 21111 XM_029345189.2 0 18 0 0 0 Q9UKJ5 3.4e-52 Cysteine-rich hydrophobic domain-containing protein 2 (BrX-like translocated in leukemia) Homo sapiens (Human) NA GO:0005794; GO:0005798; GO:0005886; GO:0043231 21112 XM_044307955.1 192 225 217 124 177 NA NA NA NA NA NA 21113 XM_029339442.2 19 14 79 70 18 NA NA NA NA NA NA 21114 XM_044307471.1 398 307 480 846 987 NA NA NA NA NA NA 21115 XM_044326514.1 79 0 20 0 3 F1QZ15 8.68e-40 EKC/KEOPS complex subunit TPRKB (PRPK-binding protein) (TP53RK-binding protein) Danio rerio (Zebrafish) (Brachydanio rerio) tRNA threonylcarbamoyladenosine modification [GO:0002949] GO:0000408; GO:0002949; GO:0005634; GO:0005737; GO:0005829 21116 XM_029344977.2 166 137 0 0 0 Q8NF64 7.82e-140 Zinc finger MIZ domain-containing protein 2 (PIAS-like protein Zimp7) Homo sapiens (Human) positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0005634; GO:0005654; GO:0005739; GO:0006357; GO:0008270; GO:0030374; GO:0043596; GO:0045944 21117 XM_044326430.1 5 0 6 3 64 NA NA NA NA NA NA 21118 XM_044316516.1 528 52 21 757 1062 NA NA NA NA NA NA 21119 XR_006396970.1 2924 3894 1161 5828 2977 NA NA NA NA NA NA 21120 XM_029326268.2 9496 34390 11392 6093 3203 NA NA NA NA NA NA 21121 XR_006397126.1 1 5 0 0 11 NA NA NA NA NA NA 21122 XM_044325740.1 25 66 19 33 145 NA NA NA NA NA NA 21123 XM_044307229.1 61 22 67 60 27 NA NA NA NA NA NA 21124 XR_006392951.1 41 2 25 5 151 NA NA NA NA NA NA 21125 XM_044317339.1 948 107 153 636 257 NA NA NA NA NA NA 21126 XM_029357184.2 14 0 63 0 64 NA NA NA NA NA NA 21127 XM_044318726.1 1070 600 329 1015 721 P79101 0 Cleavage and polyadenylation specificity factor subunit 3 (EC 3.1.27.-) (Cleavage and polyadenylation specificity factor 73 kDa subunit) (CPSF 73 kDa subunit) (mRNA 3'-end-processing endonuclease CPSF-73) Bos taurus (Bovine) mRNA 3'-end processing [GO:0031124]; mRNA 3'-end processing by stem-loop binding and cleavage [GO:0006398]; mRNA polyadenylation [GO:0006378]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087] GO:0003723; GO:0004521; GO:0004534; GO:0005847; GO:0006378; GO:0006398; GO:0008409; GO:0031124; GO:0046872; GO:1900087; GO:1990904 21128 XM_044320111.1 15 0 106 6 6 NA NA NA NA NA NA 21129 XM_044309003.1 31 268 54 260 295 NA NA NA NA NA NA 21130 XM_029340229.2 614 188 290 468 700 Q8BYR1 4.93e-122 tRNA wybutosine-synthesizing protein 4 (tRNA yW-synthesizing protein 4) (EC 2.1.1.290) (EC 2.3.1.231) (Leucine carboxyl methyltransferase 2) (p21WAF1/CIP1 promoter-interacting protein) (tRNA(Phe) (7-(3-amino-3-(methoxycarbonyl)propyl)wyosine(37)-N)-methoxycarbonyltransferase) (tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-O)-methyltransferase) Mus musculus (Mouse) C-terminal protein methylation [GO:0006481]; tRNA methylation [GO:0030488]; wybutosine biosynthetic process [GO:0031591] GO:0003880; GO:0006481; GO:0008175; GO:0030488; GO:0031591 21131 XM_044310889.1 127 28 33 57 39 Q3UQ28 3.3e-32 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 21132 XM_044310889.1 127 28 33 57 39 Q3UQ28 2.91e-31 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 21133 XM_044310889.1 127 28 33 57 39 Q3UQ28 1.17e-28 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 21134 XM_044310889.1 127 28 33 57 39 Q3UQ28 2.23e-27 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 21135 XM_044308015.1 962 916 757 880 1032 NA NA NA NA NA NA 21136 XM_044324433.1 123 126 35 263 349 NA NA NA NA NA NA 21137 XM_029356611.2 399 132 242 311 446 Q5XIT9 0 Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCase subunit beta) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 2) (3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta) Rattus norvegicus (Rat) coenzyme A metabolic process [GO:0015936]; leucine catabolic process [GO:0006552] GO:0002169; GO:0004485; GO:0005524; GO:0005739; GO:0005759; GO:0006552; GO:0015936; GO:1905202 21138 XM_044320503.1 10 10 9 3 10 NA NA NA NA NA NA 21139 XM_044309536.1 12 27 19 24 14 NA NA NA NA NA NA 21140 XR_006395213.1 56 16 27 71 35 NA NA NA NA NA NA 21141 XM_029344525.2 1988 2147 1000 2240 2650 Q5NVI3 3.74e-122 Protein Red (Cytokine IK) (IK factor) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) mitotic cell cycle [GO:0000278]; mitotic spindle assembly checkpoint signaling [GO:0007094]; mRNA splicing, via spliceosome [GO:0000398]; protein localization to kinetochore [GO:0034501] GO:0000228; GO:0000278; GO:0000398; GO:0005634; GO:0005654; GO:0005737; GO:0007094; GO:0016607; GO:0034501; GO:0042802; GO:0071005; GO:0097431 21142 XM_044308418.1 134 48 49 65 77 NA NA NA NA NA NA 21143 XM_029355800.2 74 55 3 0 27 NA NA NA NA NA NA 21144 XM_029339830.2 266 124 83 136 175 P35406 5.87e-34 D(1) dopamine receptor (Dopamine D1 receptor) Carassius auratus (Goldfish) regulation of biological quality [GO:0065008] GO:0004930; GO:0005886; GO:0065008 21145 XM_044311343.1 15 99 102 0 611 B0S5N4 1.71e-100 Plexin A3 Danio rerio (Zebrafish) (Brachydanio rerio) axon extension [GO:0048675]; branching morphogenesis of a nerve [GO:0048755]; embryonic skeletal joint morphogenesis [GO:0060272]; motor neuron axon guidance [GO:0008045]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of collateral sprouting in absence of injury [GO:0048696]; regulation of GTPase activity [GO:0043087]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287] GO:0002116; GO:0005886; GO:0007162; GO:0008045; GO:0008360; GO:0016020; GO:0017154; GO:0030334; GO:0042802; GO:0043087; GO:0048675; GO:0048696; GO:0048755; GO:0050772; GO:0060272; GO:1902287 21146 XM_044313203.1 6 0 2 0 0 NA NA NA NA NA NA 21147 XM_044329323.1 299 180 162 221 140 Q96MY7 3.96e-39 Protein FAM161B Homo sapiens (Human) cilium organization [GO:0044782] GO:0005881; GO:0015630; GO:0044782 21148 XM_029354495.2 153 0 82 56 0 Q8N531 1.22e-37 F-box/LRR-repeat protein 6 (F-box and leucine-rich repeat protein 6) (F-box protein FBL6) (FBL6A) Homo sapiens (Human) entrainment of circadian clock by photoperiod [GO:0043153]; G2/M transition of mitotic cell cycle [GO:0000086]; proteolysis [GO:0006508]; regulation of cell cycle [GO:0051726]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0000086; GO:0004842; GO:0005634; GO:0005829; GO:0006508; GO:0019005; GO:0031146; GO:0043153; GO:0051726 21149 XR_003826857.2 39 25 25 12 4 NA NA NA NA NA NA 21150 XM_044324283.1 3569 3435 1825 2281 2904 P33568 5.21e-67 Retinoblastoma-associated protein (pRb) (Rb) (pp105) Rattus norvegicus (Rat) aortic valve morphogenesis [GO:0003180]; apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; cell division [GO:0051301]; cell morphogenesis involved in neuron differentiation [GO:0048667]; cell population proliferation [GO:0008283]; cellular response to insulin stimulus [GO:0032869]; cellular response to xenobiotic stimulus [GO:0071466]; chondrocyte differentiation [GO:0002062]; digestive tract development [GO:0048565]; enucleate erythrocyte differentiation [GO:0043353]; epithelial cell proliferation [GO:0050673]; G1/S transition of mitotic cell cycle [GO:0000082]; glial cell apoptotic process [GO:0034349]; glial cell proliferation [GO:0014009]; hepatocyte apoptotic process [GO:0097284]; heterochromatin formation [GO:0031507]; maintenance of mitotic sister chromatid cohesion [GO:0034088]; myoblast differentiation [GO:0045445]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of gene expression [GO:0010629]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of hepatocyte apoptotic process [GO:1903944]; negative regulation of inflammatory response [GO:0050728]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myofibroblast differentiation [GO:1904761]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of tau-protein kinase activity [GO:1902948]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0071930]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; neuron projection development [GO:0031175]; positive regulation of collagen fibril organization [GO:1904028]; positive regulation of extracellular matrix organization [GO:1903055]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein localization to chromosome, centromeric region [GO:0071459]; Ras protein signal transduction [GO:0007265]; regulation of cell cycle [GO:0051726]; regulation of cell growth [GO:0001558]; regulation of cohesin loading [GO:0071922]; regulation of lipid kinase activity [GO:0043550]; regulation of mitotic cell cycle [GO:0007346]; sister chromatid biorientation [GO:0031134]; skeletal muscle cell differentiation [GO:0035914]; smoothened signaling pathway [GO:0007224]; spermatogenesis [GO:0007283]; striated muscle cell differentiation [GO:0051146]; tissue homeostasis [GO:0001894]; transcription by RNA polymerase II [GO:0006366] GO:0000082; GO:0000122; GO:0000785; GO:0000977; GO:0001558; GO:0001894; GO:0002062; GO:0003180; GO:0005634; GO:0005654; GO:0005667; GO:0005819; GO:0006366; GO:0006469; GO:0006915; GO:0007224; GO:0007265; GO:0007283; GO:0007346; GO:0008024; GO:0008283; GO:0008285; GO:0010629; GO:0014009; GO:0016605; GO:0019899; GO:0019900; GO:0030154; GO:0030182; GO:0030308; GO:0031134; GO:0031175; GO:0031507; GO:0031625; GO:0032869; GO:0034088; GO:0034349; GO:0035189; GO:0035914; GO:0042551; GO:0042802; GO:0043353; GO:0043433; GO:0043550; GO:0045445; GO:0045651; GO:0045786; GO:0045842; GO:0045879; GO:0045892; GO:0045930; GO:0045944; GO:0048565; GO:0048667; GO:0050673; GO:0050680; GO:0050728; GO:0051146; GO:0051219; GO:0051301; GO:0051402; GO:0051726; GO:0060090; GO:0060253; GO:0061629; GO:0061676; GO:0061793; GO:0071459; GO:0071466; GO:0071901; GO:0071922; GO:0071930; GO:0097284; GO:0097718; GO:0120163; GO:0140297; GO:1902948; GO:1903055; GO:1903944; GO:1904028; GO:1904761; GO:2000134; GO:2000679; GO:2001234 21151 XM_044323229.1 1167 533 621 1711 1881 NA NA NA NA NA NA 21152 XM_029358147.2 55 216 51 191 0 NA NA NA NA NA NA 21153 XM_029345704.2 0 0 13 0 10 NA NA NA NA NA NA 21154 XM_029352189.2 704 550 401 533 1035 Q08BH7 7.02e-71 Ubiquitin-conjugating enzyme E2 T (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme T) (Ubiquitin carrier protein T) (Ubiquitin-protein ligase T) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; protein autoubiquitination [GO:0051865]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209] GO:0000209; GO:0003682; GO:0004842; GO:0005524; GO:0005634; GO:0006281; GO:0006513; GO:0006974; GO:0051865; GO:0061631 21155 XM_029356671.2 589 465 419 497 587 Q66II5 9.05e-142 Trans-L-3-hydroxyproline dehydratase (EC 4.2.1.77) (Trans-3-hydroxy-L-proline dehydratase) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0016836; GO:0050346 21156 XM_044315187.1 312 200 1 0 136 NA NA NA NA NA NA 21157 XM_029338746.2 456 283 318 519 298 B3EWZ6 3.24e-138 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 21158 XM_029338746.2 456 283 318 519 298 B3EWZ6 1.1e-133 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 21159 XM_029338746.2 456 283 318 519 298 B3EWZ6 2.66e-131 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 21160 XM_029338746.2 456 283 318 519 298 B3EWZ6 2.59e-129 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 21161 XM_029338746.2 456 283 318 519 298 B3EWZ6 4.43e-129 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 21162 XM_029338746.2 456 283 318 519 298 B3EWZ6 1.03e-125 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 21163 XM_029338746.2 456 283 318 519 298 B3EWZ6 8.61e-114 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 21164 XM_029338746.2 456 283 318 519 298 B3EWZ6 1.29e-106 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 21165 XM_029338746.2 456 283 318 519 298 B3EWZ6 7.24e-102 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 21166 XM_029338746.2 456 283 318 519 298 B3EWZ6 1.55e-101 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 21167 XM_029338746.2 456 283 318 519 298 B3EWZ6 2.36e-97 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 21168 XM_029338746.2 456 283 318 519 298 B3EWZ6 5.7e-87 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 21169 XM_029338746.2 456 283 318 519 298 B3EWZ6 1.59e-85 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 21170 XM_029338746.2 456 283 318 519 298 B3EWZ6 2.68e-85 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 21171 XM_029338746.2 456 283 318 519 298 B3EWZ6 7.06e-81 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 21172 XM_029338746.2 456 283 318 519 298 B3EWZ6 4.07e-53 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 21173 XM_029338746.2 456 283 318 519 298 B3EWZ6 5.05e-49 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 21174 XM_044311896.1 712 378 284 428 310 Q4PZA2 4.98e-140 Endothelin-converting enzyme 1 (ECE-1) (EC 3.4.24.71) Mus musculus (Mouse) apoptotic process [GO:0006915]; axonogenesis involved in innervation [GO:0060385]; blood vessel diameter maintenance [GO:0097746]; bradykinin catabolic process [GO:0010815]; calcitonin catabolic process [GO:0010816]; ear development [GO:0043583]; embryonic digit morphogenesis [GO:0042733]; embryonic heart tube development [GO:0035050]; endothelin maturation [GO:0034959]; gene expression [GO:0010467]; heart development [GO:0007507]; hormone catabolic process [GO:0042447]; neuron projection development [GO:0031175]; peptide hormone processing [GO:0016486]; pharyngeal system development [GO:0060037]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of receptor recycling [GO:0001921]; protein processing [GO:0016485]; regulation of blood pressure [GO:0008217]; regulation of ERK1 and ERK2 cascade [GO:0070372]; response to hypoxia [GO:0001666]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; substance P catabolic process [GO:0010814]; sympathetic neuron axon guidance [GO:0097492] GO:0001666; GO:0001921; GO:0004175; GO:0004222; GO:0005768; GO:0005769; GO:0005794; GO:0005886; GO:0006915; GO:0007507; GO:0008217; GO:0008270; GO:0009897; GO:0009986; GO:0010467; GO:0010613; GO:0010814; GO:0010815; GO:0010816; GO:0016020; GO:0016485; GO:0016486; GO:0030141; GO:0031175; GO:0031410; GO:0031982; GO:0033093; GO:0034959; GO:0035050; GO:0042447; GO:0042733; GO:0042802; GO:0042803; GO:0043583; GO:0043950; GO:0045745; GO:0048471; GO:0060037; GO:0060385; GO:0070372; GO:0097492; GO:0097746; GO:1902287 21175 XR_006396007.1 38 0 0 173 4 NA NA NA NA NA NA 21176 XM_044312532.1 14 21 17 20 27 NA NA NA NA NA NA 21177 XM_029350447.2 0 54 58 0 161 Q86YA3 0 Protein ZGRF1 (GRF-type zinc finger domain-containing protein 1) Homo sapiens (Human) replication fork reversal [GO:0071932] GO:0003723; GO:0004386; GO:0005737; GO:0008270; GO:0016020; GO:0017108; GO:0071932 21178 XM_029356684.2 1713 1318 775 1344 1722 P27694 0 Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed] Homo sapiens (Human) base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA unwinding involved in DNA replication [GO:0006268]; DNA-templated DNA replication [GO:0006261]; double-strand break repair via homologous recombination [GO:0000724]; meiotic cell cycle [GO:0051321]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; protein localization to chromosome [GO:0034502]; telomere maintenance [GO:0000723]; telomere maintenance via telomerase [GO:0007004] GO:0000723; GO:0000724; GO:0000781; GO:0003684; GO:0003697; GO:0005634; GO:0005654; GO:0005662; GO:0006260; GO:0006261; GO:0006268; GO:0006281; GO:0006284; GO:0006289; GO:0006298; GO:0006310; GO:0006974; GO:0007004; GO:0016605; GO:0034502; GO:0043047; GO:0046872; GO:0051321; GO:0090734; GO:0098505 21179 XM_029344886.2 195 173 224 437 404 NA NA NA NA NA NA 21180 XM_029333501.2 0 0 202 0 0 P58027 1.08e-130 Amine oxidase [flavin-containing] A (EC 1.4.3.21) (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A) Canis lupus familiaris (Dog) (Canis familiaris) catecholamine metabolic process [GO:0006584]; neurotransmitter catabolic process [GO:0042135] GO:0005739; GO:0005741; GO:0006584; GO:0008131; GO:0042135; GO:0050660; GO:0052595; GO:0052596; GO:0097621 21181 XM_029329611.2 5 0 14 10 2 NA NA NA NA NA NA 21182 XM_044327774.1 5 258 46 88 56 NA NA NA NA NA NA 21183 XM_044325395.1 7 8 16 14 31 P48733 1.28e-29 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Bos taurus (Bovine) antibacterial innate immune response [GO:0140367]; defense response to Gram-negative bacterium [GO:0050829] GO:0000922; GO:0005201; GO:0005509; GO:0005576; GO:0005929; GO:0016020; GO:0016323; GO:0016324; GO:0031012; GO:0050829; GO:0060170; GO:0140367 21184 XR_006397239.1 134 25 0 5 6 NA NA NA NA NA NA 21185 XM_029324270.2 89 46 96 174 113 NA NA NA NA NA NA 21186 XM_029342230.2 897 909 592 908 1052 Q8R4F0 2.1e-121 Mucolipin-3 (Transient receptor potential channel mucolipin 3) (TRPML3) Mus musculus (Mouse) inner ear auditory receptor cell differentiation [GO:0042491]; locomotory behavior [GO:0007626] GO:0000421; GO:0005737; GO:0005765; GO:0005886; GO:0007626; GO:0008289; GO:0016020; GO:0031901; GO:0031902; GO:0042491; GO:0060171; GO:0072345 21187 XM_029351419.2 58 113 78 28 114 O73792 2.8e-52 Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1) Danio rerio (Zebrafish) (Brachydanio rerio) angiogenesis [GO:0001525]; blood vessel development [GO:0001568]; endothelial cell-cell adhesion [GO:0071603]; heart development [GO:0007507]; positive regulation of angiogenesis [GO:0045766]; positive regulation of kinase activity [GO:0033674]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculature development [GO:0001944] GO:0001525; GO:0001568; GO:0001944; GO:0004714; GO:0005524; GO:0005886; GO:0007169; GO:0007507; GO:0033674; GO:0043235; GO:0045766; GO:0071603 21188 XM_029337759.2 632 640 444 1184 1621 Q28BR5 0 Presequence protease, mitochondrial (EC 3.4.24.-) (Pitrilysin metalloproteinase 1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) proteolysis [GO:0006508] GO:0004222; GO:0005759; GO:0006508; GO:0046872 21189 XM_044325629.1 16 11 15 10 7 NA NA NA NA NA NA 21190 XM_029355968.2 1047 791 673 455 812 Q9VX10 9.55e-42 Putative sulfiredoxin (EC 1.8.98.2) Drosophila melanogaster (Fruit fly) cellular oxidant detoxification [GO:0098869]; cellular response to oxidative stress [GO:0034599] GO:0005524; GO:0005737; GO:0005829; GO:0032542; GO:0034599; GO:0098869 21191 XM_029351922.2 77 40 29 39 56 NA NA NA NA NA NA 21192 XM_044314392.1 9 2 49 10 0 NA NA NA NA NA NA 21193 XM_029329671.2 294 413 237 401 59 NA NA NA NA NA NA 21194 XM_029342138.2 274 0 499 314 374 NA NA NA NA NA NA 21195 XM_044310907.1 9 0 0 0 6 NA NA NA NA NA NA 21196 XM_044311745.1 8 2 11 20 13 NA NA NA NA NA NA 21197 XM_029325048.2 258 146 261 199 333 NA NA NA NA NA NA 21198 XM_029330821.2 1969 1588 1229 2415 2506 Q3UPY5 3.75e-162 Beta-galactosidase-1-like protein 2 (EC 3.2.1.-) Mus musculus (Mouse) carbohydrate metabolic process [GO:0005975] GO:0004565; GO:0005576; GO:0005764; GO:0005773; GO:0005975 21199 XR_006392819.1 109 75 96 76 127 NA NA NA NA NA NA 21200 XR_006394595.1 70 0 13 9 54 NA NA NA NA NA NA 21201 XM_029340821.2 82 57 30 18 33 P25102 1.66e-33 Histamine H2 receptor (H2R) (HH2R) (Gastric receptor I) Rattus norvegicus (Rat) cellular response to histamine [GO:0071420]; chemical synaptic transmission [GO:0007268]; digestive tract development [GO:0048565]; epithelial cell morphogenesis [GO:0003382]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; gastric acid secretion [GO:0001696]; gastrin-induced gastric acid secretion [GO:0001698]; gland development [GO:0048732]; histamine-induced gastric acid secretion [GO:0001697]; memory [GO:0007613]; negative regulation of arachidonic acid secretion [GO:1900139]; positive regulation of vasoconstriction [GO:0045907]; regulation of synaptic plasticity [GO:0048167]; toxin transport [GO:1901998]; visual learning [GO:0008542] GO:0001696; GO:0001697; GO:0001698; GO:0003382; GO:0004969; GO:0004993; GO:0005886; GO:0007187; GO:0007268; GO:0007613; GO:0008542; GO:0016020; GO:0030425; GO:0030594; GO:0045202; GO:0045907; GO:0048167; GO:0048565; GO:0048732; GO:0071420; GO:1900139; GO:1901363; GO:1901998 21202 XM_044325135.1 27 0 0 0 40 NA NA NA NA NA NA 21203 XM_029324542.2 0 165 77 0 0 Q0II76 2.18e-53 Gamma-aminobutyric acid receptor subunit rho-2 (GABA(A) receptor subunit rho-2) (GABA(C) receptor) Bos taurus (Bovine) chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid signaling pathway [GO:0007214]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165]; visual perception [GO:0007601] GO:0004890; GO:0005231; GO:0005254; GO:0005886; GO:0007165; GO:0007214; GO:0007268; GO:0007601; GO:0030594; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:1902476; GO:1902711; GO:1904315 21204 XM_044328038.1 0 0 20 0 203 Q0VFT9 5.99e-131 Trafficking protein particle complex subunit 13 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA NA 21205 XR_006395878.1 85 49 36 96 73 Q8BKE9 6.77e-45 Intraflagellar transport protein 74 homolog (Capillary morphogenesis gene 1 protein) (CMG-1) (Coiled-coil domain-containing protein 2) Mus musculus (Mouse) cilium assembly [GO:0060271]; determination of left/right symmetry [GO:0007368]; epidermis development [GO:0008544]; heart development [GO:0007507]; intraciliary anterograde transport [GO:0035720]; intraciliary transport [GO:0042073]; intraciliary transport involved in cilium assembly [GO:0035735]; keratinocyte development [GO:0003334]; keratinocyte proliferation [GO:0043616]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of keratinocyte proliferation [GO:0010839]; non-motile cilium assembly [GO:1905515]; Notch signaling pathway [GO:0007219]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0001669; GO:0003334; GO:0003682; GO:0005634; GO:0005813; GO:0005929; GO:0007219; GO:0007368; GO:0007507; GO:0008544; GO:0010839; GO:0030992; GO:0031514; GO:0033630; GO:0035720; GO:0035735; GO:0042073; GO:0043616; GO:0045944; GO:0048487; GO:0050680; GO:0060271; GO:1905515 21206 XR_006395878.1 85 49 36 96 73 Q8BKE9 6.77e-45 Intraflagellar transport protein 74 homolog (Capillary morphogenesis gene 1 protein) (CMG-1) (Coiled-coil domain-containing protein 2) Mus musculus (Mouse) cilium assembly [GO:0060271]; determination of left/right symmetry [GO:0007368]; epidermis development [GO:0008544]; heart development [GO:0007507]; intraciliary anterograde transport [GO:0035720]; intraciliary transport [GO:0042073]; intraciliary transport involved in cilium assembly [GO:0035735]; keratinocyte development [GO:0003334]; keratinocyte proliferation [GO:0043616]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of keratinocyte proliferation [GO:0010839]; non-motile cilium assembly [GO:1905515]; Notch signaling pathway [GO:0007219]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0001669; GO:0003334; GO:0003682; GO:0005634; GO:0005813; GO:0005929; GO:0007219; GO:0007368; GO:0007507; GO:0008544; GO:0010839; GO:0030992; GO:0031514; GO:0033630; GO:0035720; GO:0035735; GO:0042073; GO:0043616; GO:0045944; GO:0048487; GO:0050680; GO:0060271; GO:1905515 21207 XR_006395878.1 85 49 36 96 73 Q8BKE9 6.77e-45 Intraflagellar transport protein 74 homolog (Capillary morphogenesis gene 1 protein) (CMG-1) (Coiled-coil domain-containing protein 2) Mus musculus (Mouse) cilium assembly [GO:0060271]; determination of left/right symmetry [GO:0007368]; epidermis development [GO:0008544]; heart development [GO:0007507]; intraciliary anterograde transport [GO:0035720]; intraciliary transport [GO:0042073]; intraciliary transport involved in cilium assembly [GO:0035735]; keratinocyte development [GO:0003334]; keratinocyte proliferation [GO:0043616]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of keratinocyte proliferation [GO:0010839]; non-motile cilium assembly [GO:1905515]; Notch signaling pathway [GO:0007219]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0001669; GO:0003334; GO:0003682; GO:0005634; GO:0005813; GO:0005929; GO:0007219; GO:0007368; GO:0007507; GO:0008544; GO:0010839; GO:0030992; GO:0031514; GO:0033630; GO:0035720; GO:0035735; GO:0042073; GO:0043616; GO:0045944; GO:0048487; GO:0050680; GO:0060271; GO:1905515 21208 XR_006395878.1 85 49 36 96 73 Q8BKE9 6.77e-45 Intraflagellar transport protein 74 homolog (Capillary morphogenesis gene 1 protein) (CMG-1) (Coiled-coil domain-containing protein 2) Mus musculus (Mouse) cilium assembly [GO:0060271]; determination of left/right symmetry [GO:0007368]; epidermis development [GO:0008544]; heart development [GO:0007507]; intraciliary anterograde transport [GO:0035720]; intraciliary transport [GO:0042073]; intraciliary transport involved in cilium assembly [GO:0035735]; keratinocyte development [GO:0003334]; keratinocyte proliferation [GO:0043616]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of keratinocyte proliferation [GO:0010839]; non-motile cilium assembly [GO:1905515]; Notch signaling pathway [GO:0007219]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0001669; GO:0003334; GO:0003682; GO:0005634; GO:0005813; GO:0005929; GO:0007219; GO:0007368; GO:0007507; GO:0008544; GO:0010839; GO:0030992; GO:0031514; GO:0033630; GO:0035720; GO:0035735; GO:0042073; GO:0043616; GO:0045944; GO:0048487; GO:0050680; GO:0060271; GO:1905515 21209 XM_044323537.1 1067 2295 1036 845 491 NA NA NA NA NA NA 21210 XR_003827287.2 360 227 294 242 242 NA NA NA NA NA NA 21211 XM_044325934.1 6 0 12 6 41 NA NA NA NA NA NA 21212 XM_044319655.1 17 1 22 0 13 NA NA NA NA NA NA 21213 XR_006397265.1 72 14 0 0 35 NA NA NA NA NA NA 21214 XR_006398053.1 94 15 53 77 116 NA NA NA NA NA NA 21215 XM_044318617.1 300 170 105 504 181 NA NA NA NA NA NA 21216 XM_044326672.1 65 20 46 79 234 NA NA NA NA NA NA 21217 XM_044319416.1 17 44 14 21 47 NA NA NA NA NA NA 21218 XM_029334681.2 540 408 259 469 316 O14490 3.52e-23 Disks large-associated protein 1 (DAP-1) (Guanylate kinase-associated protein) (hGKAP) (PSD-95/SAP90-binding protein 1) (SAP90/PSD-95-associated protein 1) (SAPAP1) Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962] GO:0005886; GO:0007268; GO:0014069; GO:0044877; GO:0060090; GO:0098962; GO:0098978; GO:0099572 21219 XM_044309693.1 59 14 12 25 44 NA NA NA NA NA NA 21220 XM_029357103.2 882 549 379 740 597 P11645 3.81e-104 Uricase (EC 1.7.3.3) (Urate oxidase) Oryctolagus cuniculus (Rabbit) purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628] GO:0004846; GO:0005777; GO:0006144; GO:0019628 21221 XM_044312045.1 17 0 0 0 0 P35061 7.67e-86 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 21222 XM_029324308.2 503 583 473 1183 1357 NA NA NA NA NA NA 21223 XM_044316559.1 164 246 247 269 325 Q6ZQB6 4.87e-84 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 (EC 2.7.4.24) (Diphosphoinositol pentakisphosphate kinase 2) (Histidine acid phosphatase domain-containing protein 1) (InsP6 and PP-IP5 kinase 2) (VIP1 homolog 2) (mmVIP2) Mus musculus (Mouse) inositol metabolic process [GO:0006020]; inositol phosphate biosynthetic process [GO:0032958]; phosphorylation [GO:0016310]; sensory perception of sound [GO:0007605] GO:0000827; GO:0000828; GO:0000829; GO:0000832; GO:0005524; GO:0005829; GO:0006020; GO:0007605; GO:0016310; GO:0032958; GO:0033857; GO:0052723; GO:0052724 21224 XM_044307280.1 0 31 132 252 442 Q1LZH1 9.48e-40 Mitochondrial amidoxime reducing component 2 (mARC2) (EC 1.7.-.-) (Molybdenum cofactor sulfurase C-terminal domain-containing protein 2) (MOSC domain-containing protein 2) (Moco sulfurase C-terminal domain-containing protein 2) Bos taurus (Bovine) cellular detoxification of nitrogen compound [GO:0070458]; nitrate metabolic process [GO:0042126]; nitric oxide biosynthetic process [GO:0006809] GO:0005741; GO:0005777; GO:0006809; GO:0008940; GO:0030151; GO:0030170; GO:0042126; GO:0043546; GO:0070458; GO:0098809 21225 XM_044328269.1 1253 784 1012 1584 1383 Q7Z6G8 3.61e-73 Ankyrin repeat and sterile alpha motif domain-containing protein 1B (Amyloid-beta protein intracellular domain-associated protein 1) (AIDA-1) (E2A-PBX1-associated protein) (EB-1) Homo sapiens (Human) ephrin receptor signaling pathway [GO:0048013] GO:0005654; GO:0005813; GO:0005829; GO:0005886; GO:0014069; GO:0015030; GO:0043197; GO:0046875; GO:0048013 21226 XM_044328269.1 1253 784 1012 1584 1383 Q7Z6G8 1.24e-70 Ankyrin repeat and sterile alpha motif domain-containing protein 1B (Amyloid-beta protein intracellular domain-associated protein 1) (AIDA-1) (E2A-PBX1-associated protein) (EB-1) Homo sapiens (Human) ephrin receptor signaling pathway [GO:0048013] GO:0005654; GO:0005813; GO:0005829; GO:0005886; GO:0014069; GO:0015030; GO:0043197; GO:0046875; GO:0048013 21227 XR_006397907.1 62 16 51 35 170 NA NA NA NA NA NA 21228 XM_044326240.1 0 3 6 27 4 Q09575 1.82e-28 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 21229 XM_029356467.2 1495 1279 1226 1228 1346 P48443 4.29e-71 Retinoic acid receptor RXR-gamma (Nuclear receptor subfamily 2 group B member 3) (Retinoid X receptor gamma) Homo sapiens (Human) anatomical structure development [GO:0048856]; cell differentiation [GO:0030154]; heart development [GO:0007507]; neuron differentiation [GO:0030182]; peripheral nervous system development [GO:0007422]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of myelination [GO:0031641]; regulation of transcription by RNA polymerase II [GO:0006357]; response to retinoic acid [GO:0032526]; retinoic acid receptor signaling pathway [GO:0048384]; skeletal muscle tissue development [GO:0007519] GO:0000785; GO:0000978; GO:0000981; GO:0003707; GO:0004879; GO:0005654; GO:0005737; GO:0006357; GO:0007422; GO:0007507; GO:0007519; GO:0008270; GO:0030154; GO:0030182; GO:0031641; GO:0032526; GO:0044323; GO:0045944; GO:0048384; GO:0048856; GO:0090575; GO:0140693; GO:1990837 21230 XM_044329229.1 251 45 172 0 210 Q29RY4 7.18e-91 Zinc phosphodiesterase ELAC protein 1 (EC 3.1.26.11) (ElaC homolog protein 1) (Ribonuclease Z 1) (RNase Z 1) (tRNA 3 endonuclease 1) (tRNase Z 1) Bos taurus (Bovine) tRNA 3'-trailer cleavage [GO:0042779] GO:0005634; GO:0005654; GO:0005829; GO:0042779; GO:0042781; GO:0046872 21231 XR_006391676.1 10 3 15 0 35 NA NA NA NA NA NA 21232 XM_044317009.1 504 317 160 530 291 Q6BZW3 3.95e-26 Protein BTN1 Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica) L-arginine transmembrane transport [GO:1903826]; lysine transport [GO:0015819]; regulation of intracellular pH [GO:0051453] GO:0000324; GO:0005773; GO:0005774; GO:0015819; GO:0022857; GO:0051453; GO:1903826 21233 XM_044324256.1 144 30 49 21 479 Q4LDE5 4.51e-133 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 21234 XM_044324256.1 144 30 49 21 479 Q4LDE5 7.35e-131 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 21235 XM_044324256.1 144 30 49 21 479 Q4LDE5 5.83e-122 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 21236 XM_044324256.1 144 30 49 21 479 Q4LDE5 1.14e-101 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 21237 XM_044324256.1 144 30 49 21 479 Q4LDE5 6.75e-100 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 21238 XM_029324899.2 1008 616 658 1136 932 Q9C0H5 4.41e-153 Rho GTPase-activating protein 39 Homo sapiens (Human) postsynapse organization [GO:0099173]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] GO:0005096; GO:0005634; GO:0005737; GO:0005829; GO:0005856; GO:0007165; GO:0051056; GO:0098978; GO:0099173 21239 XM_029324899.2 1008 616 658 1136 932 Q9C0H5 2.37e-26 Rho GTPase-activating protein 39 Homo sapiens (Human) postsynapse organization [GO:0099173]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] GO:0005096; GO:0005634; GO:0005737; GO:0005829; GO:0005856; GO:0007165; GO:0051056; GO:0098978; GO:0099173 21240 XM_044316689.1 1 164 92 0 183 Q8BUZ3 2.88e-45 Tigger transposable element-derived protein 4 Mus musculus (Mouse) NA GO:0003677; GO:0005634 21241 XM_044326416.1 21 20 20 11 42 NA NA NA NA NA NA 21242 XM_029348192.2 195 56 0 0 0 Q6ZU80 2.68e-31 Centrosomal protein of 128 kDa (Cep128) Homo sapiens (Human) protein localization [GO:0008104] GO:0000922; GO:0005737; GO:0005813; GO:0005814; GO:0008104; GO:0120103 21243 XM_044324401.1 13 18 0 1 130 Q9VBW3 3.38e-25 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 21244 XM_029335193.2 307 187 157 307 260 Q9QZR0 4.75e-57 E3 ubiquitin-protein ligase RNF25 (EC 2.3.2.27) (RING finger protein 25) (RING finger protein AO7) (RING-type E3 ubiquitin transferase RNF25) Mus musculus (Mouse) positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein ubiquitination [GO:0016567] GO:0004842; GO:0005634; GO:0005829; GO:0016567; GO:0046872; GO:0051059; GO:0051092; GO:0061630 21245 XM_029350908.2 24 2 5 9 4 NA NA NA NA NA NA 21246 XM_044308240.1 22 8 9 15 11 NA NA NA NA NA NA 21247 XM_044326965.1 3 0 3 0 69 NA NA NA NA NA NA 21248 XM_029335031.2 20 10 5 3 1 NA NA NA NA NA NA 21249 XR_006393509.1 13 11 8 38 14 NA NA NA NA NA NA 21250 XM_029350682.2 183 245 124 180 128 Q9I8C7 1.65e-83 Neuronal acetylcholine receptor subunit alpha-10 (Alpha 10 nAChR) (Nicotinic acetylcholine receptor subunit alpha-10) (NACHR alpha-10) Gallus gallus (Chicken) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; response to auditory stimulus [GO:0010996]; signal transduction [GO:0007165] GO:0004888; GO:0005231; GO:0005262; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0010996; GO:0022848; GO:0030594; GO:0034220; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051899; GO:1904315 21251 XR_003825329.2 16 6 17 0 31 NA NA NA NA NA NA 21252 XM_029329540.2 0 2 15 7 0 P30974 4.32e-30 Tachykinin-like peptides receptor 86C (NKD) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; inter-male aggressive behavior [GO:0002121]; neuropeptide signaling pathway [GO:0007218]; tachykinin receptor signaling pathway [GO:0007217] GO:0002121; GO:0004995; GO:0005886; GO:0007186; GO:0007217; GO:0007218; GO:0008188; GO:0016020 21253 XR_006391284.1 17 0 0 0 7 NA NA NA NA NA NA 21254 XM_044311412.1 0 0 0 11 0 O60290 1.55e-21 Zinc finger protein 862 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006355; GO:0046872; GO:0046983 21255 XM_029347164.2 222 72 52 144 46 NA NA NA NA NA NA 21256 XM_029344259.2 190 600 345 72 305 Q6AZN6 0 Phosphatidylinositol 3-kinase catalytic subunit type 3 (PI3-kinase type 3) (PI3K type 3) (PtdIns-3-kinase type 3) (EC 2.7.1.137) (Phosphoinositide-3-kinase class 3) Xenopus laevis (African clawed frog) autophagy [GO:0006914]; cell cycle [GO:0007049]; cell division [GO:0051301]; phosphatidylinositol-mediated signaling [GO:0048015]; phosphorylation [GO:0016310]; regulation of cytokinesis [GO:0032465] GO:0005524; GO:0006914; GO:0007049; GO:0016303; GO:0016310; GO:0030496; GO:0032465; GO:0048015; GO:0051301 21257 XM_029335385.2 170 65 62 151 94 NA NA NA NA NA NA 21258 XM_044320747.1 7 17 0 3 13 NA NA NA NA NA NA 21259 XM_029330574.2 276 354 388 556 275 NA NA NA NA NA NA 21260 XM_029346998.2 118 93 90 117 261 Q90632 5.67e-40 Monocarboxylate transporter 3 (MCT 3) (Retinal epithelial membrane protein) (Solute carrier family 16 member 8) Gallus gallus (Chicken) monocarboxylic acid transport [GO:0015718] GO:0005886; GO:0008028; GO:0015293; GO:0015718; GO:0016020; GO:0016323 21261 XM_044307093.1 9 44 0 13 0 A5PJU6 5.98e-43 Hydroxylysine kinase (5-hydroxy-L-lysine kinase) (EC 2.7.1.81) (Aminoglycoside phosphotransferase domain-containing protein 1) Bos taurus (Bovine) phosphorylation [GO:0016310] GO:0005737; GO:0016310; GO:0019202; GO:0047992 21262 XR_006397857.1 7 3 5 0 13 NA NA NA NA NA NA 21263 XM_044313677.1 11 3 7 121 117 P15043 2.94e-32 ATP-dependent DNA helicase RecQ (EC 3.6.4.12) Escherichia coli (strain K12) cellular response to DNA damage stimulus [GO:0006974]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; SOS response [GO:0009432] GO:0003677; GO:0003678; GO:0005524; GO:0005694; GO:0005737; GO:0006260; GO:0006281; GO:0006310; GO:0006974; GO:0008094; GO:0008270; GO:0009378; GO:0009432; GO:0016887; GO:0017116; GO:0017117; GO:0030894; GO:0032508; GO:0043138; GO:0043590; GO:0046914 21264 XR_006397835.1 0 99 0 19 23 NA NA NA NA NA NA 21265 XM_029336996.2 19 17 12 30 23 Q28997 3.8e-45 Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor) Sus scrofa (Pig) activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; blood vessel diameter maintenance [GO:0097746]; desensitization of G protein-coupled receptor signaling pathway by arrestin [GO:0002032]; positive regulation of autophagosome maturation [GO:1901098]; positive regulation of lipophagy [GO:1904504]; positive regulation of MAPK cascade [GO:0043410]; receptor-mediated endocytosis [GO:0006898]; regulation of smooth muscle contraction [GO:0006940] GO:0002032; GO:0004941; GO:0005769; GO:0005794; GO:0005886; GO:0006898; GO:0006940; GO:0007189; GO:0007190; GO:0042803; GO:0043235; GO:0043410; GO:0051380; GO:0097746; GO:1901098; GO:1904504 21266 XM_029338822.2 2201 1126 1545 1721 1791 Q28BP9 1.03e-105 FAS-associated factor 2 (UBX domain-containing protein 8) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005783; GO:0005811 21267 XM_044308420.1 88 28 67 158 119 NA NA NA NA NA NA 21268 XR_003826668.2 39 26 80 55 110 NA NA NA NA NA NA 21269 XM_044327057.1 415 102 157 318 502 NA NA NA NA NA NA 21270 XM_029334017.2 209 136 144 200 314 Q5XG48 4.88e-45 Mediator of RNA polymerase II transcription subunit 4 (Mediator complex subunit 4) Xenopus laevis (African clawed frog) regulation of transcription by RNA polymerase II [GO:0006357] GO:0003712; GO:0006357; GO:0016592 21271 XM_029343439.2 366 157 70 257 86 NA NA NA NA NA NA 21272 XM_029332189.2 2239 1463 1217 1560 1827 Q6GQJ2 1.32e-127 Protein Jade-1 (Jade family PHD finger protein 1) (PHD finger protein 17) Xenopus laevis (African clawed frog) apoptotic process [GO:0006915] GO:0005634; GO:0005694; GO:0005737; GO:0005856; GO:0006915; GO:0042995; GO:0046872 21273 XM_044308211.1 89 0 37 98 221 Q9Z173 7.19e-75 Adhesion G protein-coupled receptor L3 (Calcium-independent alpha-latrotoxin receptor 3) (CIRL-3) (Latrophilin-3) Rattus norvegicus (Rat) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; brain development [GO:0007420]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; locomotion involved in locomotory behavior [GO:0031987]; maintenance of postsynaptic specialization structure [GO:0098880]; neuron migration [GO:0001764]; positive regulation of synapse assembly [GO:0051965]; response to cocaine [GO:0042220]; synapse assembly [GO:0007416]; synapse organization [GO:0050808] GO:0001764; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007166; GO:0007189; GO:0007416; GO:0007420; GO:0030246; GO:0030424; GO:0031987; GO:0042220; GO:0045211; GO:0050808; GO:0051965; GO:0098685; GO:0098742; GO:0098880; GO:0098978 21274 XR_006394171.1 3 15 2 5 8 NA NA NA NA NA NA 21275 XM_044325503.1 162 378 275 266 134 P23819 1.21e-89 Glutamate receptor 2 (GluR-2) (AMPA-selective glutamate receptor 2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (GluA2) Mus musculus (Mouse) cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to glycine [GO:1905430]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966] GO:0000149; GO:0001540; GO:0001919; GO:0004970; GO:0004971; GO:0005234; GO:0005783; GO:0005789; GO:0005886; GO:0007268; GO:0008021; GO:0008092; GO:0009986; GO:0014069; GO:0015276; GO:0015277; GO:0016020; GO:0019865; GO:0019901; GO:0030165; GO:0030424; GO:0030425; GO:0030426; GO:0030672; GO:0031623; GO:0032279; GO:0032281; GO:0032590; GO:0032839; GO:0032991; GO:0035235; GO:0035254; GO:0035255; GO:0036477; GO:0038023; GO:0042734; GO:0042802; GO:0043005; GO:0043025; GO:0043195; GO:0043197; GO:0043198; GO:0043204; GO:0044326; GO:0044327; GO:0044877; GO:0045184; GO:0045202; GO:0045211; GO:0048787; GO:0050806; GO:0051117; GO:0051262; GO:0051966; GO:0097060; GO:0097110; GO:0098685; GO:0098793; GO:0098839; GO:0098978; GO:0099507; GO:0099544; GO:0106033; GO:1904315; GO:1905430; GO:1990416 21276 XM_044319210.1 560 598 406 544 199 O55131 1.26e-157 Septin-7 (CDC10 protein homolog) Mus musculus (Mouse) cilium assembly [GO:0060271]; collateral sprouting [GO:0048668]; cortical cytoskeleton organization [GO:0030865]; cytoskeleton-dependent cytokinesis [GO:0061640]; dendritic spine morphogenesis [GO:0060997]; mitotic cytokinesis [GO:0000281]; positive regulation of non-motile cilium assembly [GO:1902857]; postsynapse organization [GO:0099173]; pseudopodium retraction [GO:0031270]; regulation of embryonic cell shape [GO:0016476]; spermatogenesis [GO:0007283] GO:0000281; GO:0000776; GO:0001725; GO:0003924; GO:0005525; GO:0005634; GO:0005819; GO:0005930; GO:0005938; GO:0005940; GO:0007283; GO:0015630; GO:0016020; GO:0016476; GO:0030496; GO:0030865; GO:0031105; GO:0031270; GO:0032153; GO:0032154; GO:0032156; GO:0032160; GO:0032991; GO:0042734; GO:0042802; GO:0043005; GO:0043025; GO:0043209; GO:0043679; GO:0045202; GO:0048668; GO:0060090; GO:0060271; GO:0060997; GO:0061640; GO:0097227; GO:0097730; GO:0098978; GO:0099173; GO:0099186; GO:0150050; GO:1902857 21277 XM_044321744.1 0 11 0 28 24 NA NA NA NA NA NA 21278 XM_029332766.2 14 13 0 18 14 P84023 0 Mothers against decapentaplegic homolog 3 (MAD homolog 3) (Mad3) (Mothers against DPP homolog 3) (SMAD family member 3) (SMAD 3) (Smad3) Gallus gallus (Chicken) activin receptor signaling pathway [GO:0032924]; anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; positive regulation of transcription by RNA polymerase II [GO:0045944]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0000978; GO:0000981; GO:0000987; GO:0003700; GO:0005634; GO:0005667; GO:0005737; GO:0007179; GO:0009653; GO:0030154; GO:0032924; GO:0045944; GO:0046872; GO:0060395; GO:0070411; GO:0071141; GO:0071144 21279 XM_029356841.2 0 2 11 11 6 NA NA NA NA NA NA 21280 XM_029354260.2 310 445 293 755 918 Q05084 8.37e-101 Islet cell autoantigen 1 (69 kDa islet cell autoantigen) (ICA69) (Islet cell autoantigen p69) (ICAp69) (p69) Homo sapiens (Human) neurotransmitter transport [GO:0006836]; regulation of transport [GO:0051049] GO:0000139; GO:0005737; GO:0005794; GO:0005829; GO:0006836; GO:0019904; GO:0030667; GO:0030672; GO:0043231; GO:0051049; GO:0140090 21281 XM_029346487.2 9 8 4 0 0 NA NA NA NA NA NA 21282 XR_006398064.1 163 71 77 109 109 NA NA NA NA NA NA 21283 XM_044308462.1 18 0 0 17 16 NA NA NA NA NA NA 21284 XM_029329681.2 675 682 589 641 93 Q8BW96 6e-149 Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase I delta) (CaM-KI delta) (CaMKI delta) (CaM kinase ID) (CaMKI-like protein kinase) (CKLiK) (mCKLiK) Mus musculus (Mouse) inflammatory response [GO:0006954]; negative regulation of apoptotic process [GO:0043066]; nervous system development [GO:0007399]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of neuron projection development [GO:0010976]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of phagocytosis [GO:0050766]; positive regulation of respiratory burst [GO:0060267]; regulation of dendrite development [GO:0050773]; regulation of granulocyte chemotaxis [GO:0071622] GO:0004683; GO:0005516; GO:0005524; GO:0005634; GO:0005737; GO:0006954; GO:0007399; GO:0010976; GO:0018105; GO:0032793; GO:0043065; GO:0043066; GO:0050766; GO:0050773; GO:0060267; GO:0071622; GO:0090023; GO:0106310 21285 XM_044316458.1 189 249 90 145 250 NA NA NA NA NA NA 21286 XM_029345215.2 492 631 133 258 331 Q08DT6 1.77e-26 39S ribosomal protein L47, mitochondrial (L47mt) (MRP-L47) Bos taurus (Bovine) translation [GO:0006412] GO:0003735; GO:0005743; GO:0005762; GO:0006412 21287 XM_044315169.1 60 0 151 231 300 P97321 3.53e-37 Prolyl endopeptidase FAP (EC 3.4.21.26) (Dipeptidyl peptidase FAP) (EC 3.4.14.5) (Fibroblast activation protein alpha) (FAPalpha) (Gelatine degradation protease FAP) (EC 3.4.21.-) (Integral membrane serine protease) (Post-proline cleaving enzyme) (Serine integral membrane protease) (SIMP) (Surface-expressed protease) (Seprase) [Cleaved into: Antiplasmin-cleaving enzyme FAP, soluble form (APCE) (EC 3.4.14.5) (EC 3.4.21.-) (EC 3.4.21.26)] Mus musculus (Mouse) angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; melanocyte apoptotic process [GO:1902362]; melanocyte proliferation [GO:0097325]; negative regulation of cell proliferation involved in contact inhibition [GO:0060244]; negative regulation of extracellular matrix disassembly [GO:0010716]; negative regulation of extracellular matrix organization [GO:1903054]; positive regulation of execution phase of apoptosis [GO:1900119]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of cell cycle [GO:0051726]; regulation of collagen catabolic process [GO:0010710] GO:0001525; GO:0002020; GO:0004175; GO:0004252; GO:0005178; GO:0005615; GO:0005886; GO:0006508; GO:0007155; GO:0008233; GO:0008236; GO:0008239; GO:0009986; GO:0010710; GO:0010716; GO:0030027; GO:0031258; GO:0032587; GO:0042802; GO:0042803; GO:0043542; GO:0045177; GO:0045178; GO:0051603; GO:0051726; GO:0060244; GO:0070161; GO:0097325; GO:1900119; GO:1902362; GO:1903054; GO:1905368 21288 XM_044315169.1 60 0 151 231 300 P97321 3.53e-37 Prolyl endopeptidase FAP (EC 3.4.21.26) (Dipeptidyl peptidase FAP) (EC 3.4.14.5) (Fibroblast activation protein alpha) (FAPalpha) (Gelatine degradation protease FAP) (EC 3.4.21.-) (Integral membrane serine protease) (Post-proline cleaving enzyme) (Serine integral membrane protease) (SIMP) (Surface-expressed protease) (Seprase) [Cleaved into: Antiplasmin-cleaving enzyme FAP, soluble form (APCE) (EC 3.4.14.5) (EC 3.4.21.-) (EC 3.4.21.26)] Mus musculus (Mouse) angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; melanocyte apoptotic process [GO:1902362]; melanocyte proliferation [GO:0097325]; negative regulation of cell proliferation involved in contact inhibition [GO:0060244]; negative regulation of extracellular matrix disassembly [GO:0010716]; negative regulation of extracellular matrix organization [GO:1903054]; positive regulation of execution phase of apoptosis [GO:1900119]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of cell cycle [GO:0051726]; regulation of collagen catabolic process [GO:0010710] GO:0001525; GO:0002020; GO:0004175; GO:0004252; GO:0005178; GO:0005615; GO:0005886; GO:0006508; GO:0007155; GO:0008233; GO:0008236; GO:0008239; GO:0009986; GO:0010710; GO:0010716; GO:0030027; GO:0031258; GO:0032587; GO:0042802; GO:0042803; GO:0043542; GO:0045177; GO:0045178; GO:0051603; GO:0051726; GO:0060244; GO:0070161; GO:0097325; GO:1900119; GO:1902362; GO:1903054; GO:1905368 21289 XM_044315169.1 60 0 151 231 300 P97321 3.53e-37 Prolyl endopeptidase FAP (EC 3.4.21.26) (Dipeptidyl peptidase FAP) (EC 3.4.14.5) (Fibroblast activation protein alpha) (FAPalpha) (Gelatine degradation protease FAP) (EC 3.4.21.-) (Integral membrane serine protease) (Post-proline cleaving enzyme) (Serine integral membrane protease) (SIMP) (Surface-expressed protease) (Seprase) [Cleaved into: Antiplasmin-cleaving enzyme FAP, soluble form (APCE) (EC 3.4.14.5) (EC 3.4.21.-) (EC 3.4.21.26)] Mus musculus (Mouse) angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; melanocyte apoptotic process [GO:1902362]; melanocyte proliferation [GO:0097325]; negative regulation of cell proliferation involved in contact inhibition [GO:0060244]; negative regulation of extracellular matrix disassembly [GO:0010716]; negative regulation of extracellular matrix organization [GO:1903054]; positive regulation of execution phase of apoptosis [GO:1900119]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of cell cycle [GO:0051726]; regulation of collagen catabolic process [GO:0010710] GO:0001525; GO:0002020; GO:0004175; GO:0004252; GO:0005178; GO:0005615; GO:0005886; GO:0006508; GO:0007155; GO:0008233; GO:0008236; GO:0008239; GO:0009986; GO:0010710; GO:0010716; GO:0030027; GO:0031258; GO:0032587; GO:0042802; GO:0042803; GO:0043542; GO:0045177; GO:0045178; GO:0051603; GO:0051726; GO:0060244; GO:0070161; GO:0097325; GO:1900119; GO:1902362; GO:1903054; GO:1905368 21290 XM_029348860.2 38 46 40 51 12 O75081 3.19e-108 Protein CBFA2T3 (MTG8-related protein 2) (Myeloid translocation gene on chromosome 16 protein) (hMTG16) (Zinc finger MYND domain-containing protein 4) Homo sapiens (Human) granulocyte differentiation [GO:0030851]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of glycolytic process [GO:0045820]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; regulation of aerobic respiration [GO:1903715]; response to hypoxia [GO:0001666] GO:0000139; GO:0001666; GO:0003714; GO:0005634; GO:0005654; GO:0005730; GO:0008285; GO:0030851; GO:0032436; GO:0045820; GO:0045892; GO:0046872; GO:1903715 21291 XM_029348860.2 38 46 40 51 12 O75081 3.19e-108 Protein CBFA2T3 (MTG8-related protein 2) (Myeloid translocation gene on chromosome 16 protein) (hMTG16) (Zinc finger MYND domain-containing protein 4) Homo sapiens (Human) granulocyte differentiation [GO:0030851]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of glycolytic process [GO:0045820]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; regulation of aerobic respiration [GO:1903715]; response to hypoxia [GO:0001666] GO:0000139; GO:0001666; GO:0003714; GO:0005634; GO:0005654; GO:0005730; GO:0008285; GO:0030851; GO:0032436; GO:0045820; GO:0045892; GO:0046872; GO:1903715 21292 XM_029347527.2 35 31 37 61 80 NA NA NA NA NA NA 21293 XM_029349810.2 3914 3695 1955 3219 2322 Q5U680 2.22e-83 S-adenosylmethionine mitochondrial carrier protein (Mitochondrial S-adenosylmethionine transporter) (Solute carrier family 25 member 26) Mus musculus (Mouse) S-adenosyl-L-methionine transport [GO:0015805] GO:0000095; GO:0005739; GO:0005743; GO:0015805 21294 XM_029335939.2 165 110 40 110 26 Q5E9Y5 2.33e-28 Decapping and exoribonuclease protein (DXO) (EC 3.6.1.-) (5'-3' exoribonuclease DXO) (EC 3.1.13.-) (Dom-3 homolog Z) (NAD-capped RNA hydrolase DXO) (DeNADding enzyme DXO) (EC 3.6.1.-) Bos taurus (Bovine) mRNA catabolic process [GO:0006402]; NAD-cap decapping [GO:0110155]; nuclear mRNA surveillance [GO:0071028]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; RNA destabilization [GO:0050779] GO:0000166; GO:0000287; GO:0000956; GO:0003729; GO:0005634; GO:0005829; GO:0006402; GO:0008409; GO:0034353; GO:0050779; GO:0071028; GO:0090305; GO:0110152; GO:0110155 21295 XR_006395253.1 311 393 173 620 388 Q6DFF6 7.96e-42 Kelch-like protein 20 Xenopus laevis (African clawed frog) Golgi to endosome transport [GO:0006895]; negative regulation of apoptotic process [GO:0043066]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K33-linked ubiquitination [GO:1990390]; protein transport [GO:0015031]; protein ubiquitination [GO:0016567] GO:0004842; GO:0005737; GO:0005802; GO:0005829; GO:0006895; GO:0015031; GO:0016567; GO:0016605; GO:0019964; GO:0031463; GO:0043066; GO:0043161; GO:0048471; GO:1990390 21296 XR_006395253.1 311 393 173 620 388 Q6DFF6 7.96e-42 Kelch-like protein 20 Xenopus laevis (African clawed frog) Golgi to endosome transport [GO:0006895]; negative regulation of apoptotic process [GO:0043066]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K33-linked ubiquitination [GO:1990390]; protein transport [GO:0015031]; protein ubiquitination [GO:0016567] GO:0004842; GO:0005737; GO:0005802; GO:0005829; GO:0006895; GO:0015031; GO:0016567; GO:0016605; GO:0019964; GO:0031463; GO:0043066; GO:0043161; GO:0048471; GO:1990390 21297 XM_044325499.1 698 230 8 9 2 NA NA NA NA NA NA 21298 XR_006397290.1 228 112 145 111 68 NA NA NA NA NA NA 21299 XM_044312913.1 960 301 252 429 182 A6QLE5 9.08e-30 NACHT, LRR and PYD domains-containing protein 3 (EC 3.6.4.-) Bos taurus (Bovine) detection of biotic stimulus [GO:0009595]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; NLRP3 inflammasome complex assembly [GO:0044546]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type 2 immune response [GO:0002830]; protein homooligomerization [GO:0051260]; regulation of inflammatory response [GO:0050727] GO:0002674; GO:0002830; GO:0005524; GO:0005576; GO:0005634; GO:0005737; GO:0005783; GO:0006954; GO:0009595; GO:0016020; GO:0016887; GO:0031021; GO:0032731; GO:0032753; GO:0035591; GO:0043280; GO:0043531; GO:0043565; GO:0044546; GO:0045087; GO:0045630; GO:0045944; GO:0050727; GO:0050729; GO:0051260; GO:0070273; GO:0072559; GO:0140297; GO:0140299; GO:1901223; GO:1901981; GO:2000553 21300 XM_029336206.2 1593 692 419 1236 1103 Q8N945 3.96e-38 PRELI domain-containing protein 2 Homo sapiens (Human) phospholipid transport [GO:0015914] GO:0005758; GO:0015914; GO:1990050 21301 XM_044322582.1 168 70 103 66 374 Q18297 3.2e-139 Transient receptor potential cation channel subfamily A member 1 homolog Caenorhabditis elegans response to stimulus [GO:0050896] GO:0005216; GO:0005886; GO:0043025; GO:0050896; GO:0097730 21302 XM_044322582.1 168 70 103 66 374 Q18297 2.02e-33 Transient receptor potential cation channel subfamily A member 1 homolog Caenorhabditis elegans response to stimulus [GO:0050896] GO:0005216; GO:0005886; GO:0043025; GO:0050896; GO:0097730 21303 XR_006392414.1 4 5 0 6 14 NA NA NA NA NA NA 21304 XM_029349336.2 334 228 243 474 422 Q7SXF6 9.48e-85 Cysteine-rich with EGF-like domain protein 2 Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005509; GO:0005576; GO:0005783 21305 XM_029340313.2 1000 987 806 1008 1356 B5DE93 0 Cyclin-dependent kinase 12 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 12) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) mRNA processing [GO:0006397]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; regulation of MAP kinase activity [GO:0043405]; RNA splicing [GO:0008380] GO:0004693; GO:0005524; GO:0006397; GO:0008353; GO:0008380; GO:0016607; GO:0019908; GO:0043405; GO:0070816; GO:0106310 21306 XM_029328299.2 8851 11261 5210 8705 5298 Q07817 7.98e-21 Bcl-2-like protein 1 (Bcl2-L-1) (Apoptosis regulator Bcl-X) Homo sapiens (Human) apoptotic mitochondrial changes [GO:0008637]; apoptotic process in bone marrow cell [GO:0071839]; cellular response to alkaloid [GO:0071312]; cellular response to amino acid stimulus [GO:0071230]; cellular response to gamma radiation [GO:0071480]; defense response to virus [GO:0051607]; dendritic cell apoptotic process [GO:0097048]; dendritic cell proliferation [GO:0044565]; ectopic germ cell programmed cell death [GO:0035234]; endocytosis [GO:0006897]; epithelial cell proliferation [GO:0050673]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fertilization [GO:0009566]; germ cell development [GO:0007281]; hepatocyte apoptotic process [GO:0097284]; in utero embryonic development [GO:0001701]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; male gonad development [GO:0008584]; mitochondrion morphogenesis [GO:0070584]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of dendritic cell apoptotic process [GO:2000669]; negative regulation of developmental process [GO:0051093]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of execution phase of apoptosis [GO:1900118]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902230]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein localization to plasma membrane [GO:1903077]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; negative regulation of reproductive process [GO:2000242]; neuron apoptotic process [GO:0051402]; ovarian follicle development [GO:0001541]; positive regulation of mononuclear cell proliferation [GO:0032946]; regulation of cytokinesis [GO:0032465]; regulation of growth [GO:0040008]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane potential [GO:0051881]; release of cytochrome c from mitochondria [GO:0001836]; response to cycloheximide [GO:0046898]; response to cytokine [GO:0034097]; spermatogenesis [GO:0007283]; suppression by virus of host apoptotic process [GO:0019050] GO:0001541; GO:0001701; GO:0001836; GO:0005737; GO:0005739; GO:0005741; GO:0005743; GO:0005759; GO:0005783; GO:0005813; GO:0005829; GO:0006897; GO:0007281; GO:0007283; GO:0008584; GO:0008630; GO:0008637; GO:0009566; GO:0010507; GO:0019050; GO:0019901; GO:0030672; GO:0031965; GO:0032465; GO:0032946; GO:0034097; GO:0035234; GO:0040008; GO:0042802; GO:0042803; GO:0043066; GO:0043524; GO:0044565; GO:0046898; GO:0046902; GO:0046982; GO:0050673; GO:0051093; GO:0051402; GO:0051434; GO:0051607; GO:0051881; GO:0070584; GO:0071230; GO:0071312; GO:0071480; GO:0071839; GO:0090201; GO:0097048; GO:0097136; GO:0097143; GO:0097192; GO:0097284; GO:1900118; GO:1901029; GO:1902042; GO:1902230; GO:1902236; GO:1903077; GO:2000242; GO:2000669; GO:2000811; GO:2001240; GO:2001243 21307 XM_044310464.1 12 98 61 0 37 NA NA NA NA NA NA 21308 XR_006393383.1 15 25 9 0 30 NA NA NA NA NA NA 21309 XM_044319908.1 650 980 783 679 917 Q12904 1.77e-79 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (Multisynthase complex auxiliary component p43) [Cleaved into: Endothelial monocyte-activating polypeptide 2 (EMAP-2) (Endothelial monocyte-activating polypeptide II) (EMAP-II) (Small inducible cytokine subfamily E member 1)] Homo sapiens (Human) angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell-cell signaling [GO:0007267]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; negative regulation of endothelial cell proliferation [GO:0001937]; positive regulation of glucagon secretion [GO:0070094]; translation [GO:0006412] GO:0000049; GO:0001525; GO:0001937; GO:0005125; GO:0005615; GO:0005634; GO:0005783; GO:0005794; GO:0005829; GO:0006412; GO:0006915; GO:0006954; GO:0007267; GO:0009986; GO:0016020; GO:0017101; GO:0042803; GO:0050900; GO:0051020; GO:0070094 21310 XM_029350245.2 273 0 176 135 474 NA NA NA NA NA NA 21311 XM_044319607.1 145 44 9 106 68 NA NA NA NA NA NA 21312 XM_044327043.1 4 0 14 4 0 A4IGL7 2.8e-86 Peroxidasin (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0005576; GO:0005604; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0031012; GO:0042744; GO:0046872; GO:0051260; GO:0070207; GO:0070831; GO:0071711; GO:0140825 21313 XM_029338057.2 18 43 13 40 3 Q0VCJ7 8.27e-38 Ras-related and estrogen-regulated growth inhibitor (EC 3.6.5.2) Bos taurus (Bovine) negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; Ras protein signal transduction [GO:0007265]; response to hormone [GO:0009725] GO:0001650; GO:0003924; GO:0003925; GO:0005525; GO:0005654; GO:0005829; GO:0005886; GO:0007265; GO:0008285; GO:0009725; GO:0019003; GO:0030308 21314 XM_029327392.2 1418 916 1079 857 1091 P17863 1.82e-47 Transforming protein Ski Avian erythroblastosis virus (strain Sloan-Kettering) NA GO:0046332; GO:0110165 21315 XM_044313304.1 940 1107 499 1250 1160 Q9Z254 4.35e-101 PDZ domain-containing protein GIPC1 (GAIP C-terminus-interacting protein) (GLUT1 C-terminal-binding protein) (GLUT1CBP) (RGS-GAIP-interacting protein) (RGS19-interacting protein 1) (Synectin) Rattus norvegicus (Rat) cellular response to interleukin-7 [GO:0098761]; chemical synaptic transmission [GO:0007268]; endothelial cell migration [GO:0043542]; glutamate secretion [GO:0014047]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; positive regulation of cytokinesis [GO:0032467]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; protein targeting [GO:0006605]; regulation of protein stability [GO:0031647]; regulation of synaptic plasticity [GO:0048167]; regulation of synaptic vesicle exocytosis [GO:2000300] GO:0003779; GO:0005102; GO:0005737; GO:0005829; GO:0005903; GO:0005938; GO:0006605; GO:0007268; GO:0008021; GO:0012506; GO:0014047; GO:0016020; GO:0017022; GO:0030139; GO:0030165; GO:0030511; GO:0031410; GO:0031647; GO:0032435; GO:0032467; GO:0042802; GO:0043197; GO:0043198; GO:0043542; GO:0048023; GO:0048167; GO:0098685; GO:0098761; GO:0098793; GO:0098794; GO:0098978; GO:0099171; GO:2000300 21316 XM_044324113.1 3 7 13 27 24 NA NA NA NA NA NA 21317 XR_006396341.1 0 44 0 69 35 NA NA NA NA NA NA 21318 XM_029348703.2 1017 771 544 775 700 NA NA NA NA NA NA 21319 XM_044309679.1 79 121 45 8 74 Q80XJ3 7.59e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 21320 XM_029335936.2 0 0 0 0 71 O14508 1.79e-27 Suppressor of cytokine signaling 2 (SOCS-2) (Cytokine-inducible SH2 protein 2) (CIS-2) (STAT-induced STAT inhibitor 2) (SSI-2) Homo sapiens (Human) cellular response to hormone stimulus [GO:0032870]; growth hormone receptor signaling pathway [GO:0060396]; intracellular signal transduction [GO:0035556]; lactation [GO:0007595]; mammary gland alveolus development [GO:0060749]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; phosphatidylinositol phosphate biosynthetic process [GO:0046854]; positive regulation of neuron differentiation [GO:0045666]; protein ubiquitination [GO:0016567]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of cell growth [GO:0001558]; regulation of signal transduction [GO:0009966]; response to estradiol [GO:0032355] GO:0001558; GO:0005131; GO:0005159; GO:0005737; GO:0005829; GO:0005942; GO:0007259; GO:0007595; GO:0008269; GO:0009966; GO:0016567; GO:0032355; GO:0032870; GO:0035556; GO:0040015; GO:0043066; GO:0045666; GO:0046426; GO:0046854; GO:0046935; GO:0060396; GO:0060749 21321 XR_006396864.1 15 2 6 1 5 NA NA NA NA NA NA 21322 XR_003825549.2 63 158 374 112 55 NA NA NA NA NA NA 21323 XM_044326471.1 9 0 0 0 0 NA NA NA NA NA NA 21324 XM_029341617.2 0 0 12 212 872 Q5PRF9 1.49e-73 Protein Smaug homolog 2 (Smaug 2) (hSmaug2) (Sterile alpha motif domain-containing protein 4B) (SAM domain-containing protein 4B) Homo sapiens (Human) nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289] GO:0000289; GO:0000932; GO:0003723; GO:0003729; GO:0005634; GO:0005829; GO:0030371 21325 XM_044325701.1 115 44 85 95 153 NA NA NA NA NA NA 21326 XM_029331134.2 32 4 11 7 35 Q9UHC6 1.54e-34 Contactin-associated protein-like 2 (Cell recognition molecule Caspr2) Homo sapiens (Human) adult behavior [GO:0030534]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell population proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; clustering of voltage-gated potassium channels [GO:0045163]; learning [GO:0007612]; limbic system development [GO:0021761]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuron recognition [GO:0008038]; positive regulation of gap junction assembly [GO:1903598]; protein localization to juxtaparanode region of axon [GO:0071205]; social behavior [GO:0035176]; striatum development [GO:0021756]; superior temporal gyrus development [GO:0071109]; thalamus development [GO:0021794]; transmission of nerve impulse [GO:0019226]; vocal learning [GO:0042297]; vocalization behavior [GO:0071625] GO:0005769; GO:0005794; GO:0007155; GO:0007420; GO:0007612; GO:0008038; GO:0008076; GO:0008283; GO:0009986; GO:0016020; GO:0019226; GO:0019899; GO:0021756; GO:0021761; GO:0021794; GO:0021987; GO:0030424; GO:0030425; GO:0030534; GO:0030673; GO:0031175; GO:0033010; GO:0035176; GO:0042297; GO:0043025; GO:0043204; GO:0044224; GO:0045163; GO:0048812; GO:0071109; GO:0071205; GO:0071625; GO:1903598 21327 XM_044319186.1 382 471 152 164 557 NA NA NA NA NA NA 21328 XM_044328525.1 850 628 743 675 807 NA NA NA NA NA NA 21329 XM_044329191.1 21 6 3 16 0 NA NA NA NA NA NA 21330 XM_044320333.1 1431 763 811 1758 2484 O95714 0 E3 ubiquitin-protein ligase HERC2 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 2) (HECT-type E3 ubiquitin transferase HERC2) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; intracellular protein transport [GO:0006886]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; spermatogenesis [GO:0007283] GO:0005085; GO:0005634; GO:0005654; GO:0005737; GO:0005814; GO:0005829; GO:0005886; GO:0006281; GO:0006886; GO:0006974; GO:0007283; GO:0008270; GO:0016020; GO:0016567; GO:0031625; GO:0032183; GO:0043161; GO:0061630 21331 XM_029333588.2 1460 1490 790 1497 1554 O35459 1.86e-116 Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (EC 5.3.3.-) Mus musculus (Mouse) fatty acid beta-oxidation [GO:0006635] GO:0005739; GO:0005777; GO:0006635; GO:0051750 21332 XM_044316727.1 54 0 1 120 24 NA NA NA NA NA NA 21333 XM_044319496.1 0 0 8 63 101 Q6ZQR2 4.59e-33 Cilia- and flagella-associated protein 77 Homo sapiens (Human) NA GO:0005929 21334 XM_029329625.2 212 117 237 372 142 Q9EQD2 2.42e-21 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 21335 XM_029338926.2 365 119 545 646 261 Q20191 2.93e-44 Zinc metalloproteinase nas-13 (EC 3.4.24.-) (Nematode astacin 13) Caenorhabditis elegans proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0006508; GO:0008270 21336 XR_006392676.1 175 134 235 207 564 NA NA NA NA NA NA 21337 XM_044306840.1 2220 1258 623 2094 923 NA NA NA NA NA NA 21338 XM_029343301.2 89 5 66 35 116 Q8NCQ5 5.12e-43 F-box only protein 15 Homo sapiens (Human) NA GO:0005829; GO:0019005 21339 XM_029334070.2 2208 2194 926 3192 2578 NA NA NA NA NA NA 21340 XM_044321704.1 0 75 0 369 492 B6CHA3 0 E3 ubiquitin-protein ligase UHRF1 (EC 2.3.2.27) (Nuclear zinc finger protein Np95) (XNp95) (RING-type E3 ubiquitin transferase UHRF1) (Ubiquitin-like PHD and RING finger domain-containing protein 1) (Ubiquitin-like-containing PHD and RING finger domains protein 1) Xenopus laevis (African clawed frog) cell cycle [GO:0007049]; chromatin organization [GO:0006325]; histone ubiquitination [GO:0016574]; maintenance of DNA methylation [GO:0010216]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein autoubiquitination [GO:0051865]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000122; GO:0000785; GO:0000791; GO:0000792; GO:0004842; GO:0005634; GO:0005657; GO:0006325; GO:0006511; GO:0007049; GO:0008270; GO:0010216; GO:0016574; GO:0035064; GO:0042393; GO:0044729; GO:0051865 21341 XM_029344241.2 2183 2532 1110 1862 3646 NA NA NA NA NA NA 21342 XM_029348827.2 274 312 185 290 316 Q5JS54 7.37e-33 Proteasome assembly chaperone 4 (PAC-4) (hPAC4) Homo sapiens (Human) proteasome assembly [GO:0043248] GO:0032991; GO:0043248; GO:0044877 21343 XR_006397511.1 23 0 31 2 117 NA NA NA NA NA NA 21344 XM_044328329.1 938 540 485 605 585 Q8IWQ3 0 Serine/threonine-protein kinase BRSK2 (EC 2.7.11.1) (Brain-selective kinase 2) (EC 2.7.11.26) (Brain-specific serine/threonine-protein kinase 2) (BR serine/threonine-protein kinase 2) (Serine/threonine-protein kinase 29) (Serine/threonine-protein kinase SAD-A) Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; axonogenesis [GO:0007409]; cell division [GO:0051301]; cellular response to glucose starvation [GO:0042149]; ERAD pathway [GO:0036503]; establishment of cell polarity [GO:0030010]; exocytosis [GO:0006887]; G2/M transition of mitotic cell cycle [GO:0000086]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; neuron differentiation [GO:0030182]; peptidyl-serine phosphorylation [GO:0018105]; protein phosphorylation [GO:0006468]; regulation of ATP-dependent activity [GO:0043462]; regulation of axonogenesis [GO:0050770]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; regulation of neuron projection development [GO:0010975]; regulation of retrograde protein transport, ER to cytosol [GO:1904152]; regulation of synaptic vesicle clustering [GO:2000807] GO:0000086; GO:0000287; GO:0004674; GO:0005524; GO:0005737; GO:0005783; GO:0005813; GO:0006468; GO:0006887; GO:0007409; GO:0010975; GO:0018105; GO:0019901; GO:0030010; GO:0030182; GO:0031532; GO:0035556; GO:0036503; GO:0042149; GO:0043462; GO:0048156; GO:0048471; GO:0050321; GO:0050770; GO:0051117; GO:0051301; GO:0060590; GO:0061178; GO:0070059; GO:0090176; GO:0106310; GO:0150034; GO:1904152; GO:2000807 21345 XM_029329543.2 0 0 0 0 17 P30974 2.29e-30 Tachykinin-like peptides receptor 86C (NKD) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; inter-male aggressive behavior [GO:0002121]; neuropeptide signaling pathway [GO:0007218]; tachykinin receptor signaling pathway [GO:0007217] GO:0002121; GO:0004995; GO:0005886; GO:0007186; GO:0007217; GO:0007218; GO:0008188; GO:0016020 21346 XM_029349596.2 166 192 276 325 410 NA NA NA NA NA NA 21347 XM_029335590.2 1244 996 1040 1603 1410 NA NA NA NA NA NA 21348 XM_029349306.2 346 361 294 410 472 NA NA NA NA NA NA 21349 XR_006395275.1 417 479 238 692 1102 NA NA NA NA NA NA 21350 XM_029351157.2 219 208 117 66 140 NA NA NA NA NA NA 21351 XM_029349112.2 3494 2731 1417 2879 2944 NA NA NA NA NA NA 21352 XM_044311073.1 434 117 97 99 62 P16157 2.49e-85 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 21353 XM_044311073.1 434 117 97 99 62 P16157 1.75e-72 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 21354 XM_044311073.1 434 117 97 99 62 P16157 1.11e-54 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 21355 XR_006397023.1 84 67 88 78 146 NA NA NA NA NA NA 21356 XM_029358533.2 865 530 475 651 738 Q12830 2.01e-82 Nucleosome-remodeling factor subunit BPTF (Bromodomain and PHD finger-containing transcription factor) (Fetal Alz-50 clone 1 protein) (Fetal Alzheimer antigen) Homo sapiens (Human) anterior/posterior pattern specification [GO:0009952]; brain development [GO:0007420]; chromatin remodeling [GO:0006338]; embryonic placenta development [GO:0001892]; endoderm development [GO:0007492]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000785; GO:0000978; GO:0001892; GO:0005634; GO:0005654; GO:0005737; GO:0006338; GO:0006355; GO:0006357; GO:0007420; GO:0007492; GO:0009952; GO:0016589; GO:0035064; GO:0043565; GO:0045944; GO:0046872; GO:0070062; GO:1904949 21357 XM_029358533.2 865 530 475 651 738 Q12830 2.39e-63 Nucleosome-remodeling factor subunit BPTF (Bromodomain and PHD finger-containing transcription factor) (Fetal Alz-50 clone 1 protein) (Fetal Alzheimer antigen) Homo sapiens (Human) anterior/posterior pattern specification [GO:0009952]; brain development [GO:0007420]; chromatin remodeling [GO:0006338]; embryonic placenta development [GO:0001892]; endoderm development [GO:0007492]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000785; GO:0000978; GO:0001892; GO:0005634; GO:0005654; GO:0005737; GO:0006338; GO:0006355; GO:0006357; GO:0007420; GO:0007492; GO:0009952; GO:0016589; GO:0035064; GO:0043565; GO:0045944; GO:0046872; GO:0070062; GO:1904949 21358 XM_029358533.2 865 530 475 651 738 Q12830 1.34e-46 Nucleosome-remodeling factor subunit BPTF (Bromodomain and PHD finger-containing transcription factor) (Fetal Alz-50 clone 1 protein) (Fetal Alzheimer antigen) Homo sapiens (Human) anterior/posterior pattern specification [GO:0009952]; brain development [GO:0007420]; chromatin remodeling [GO:0006338]; embryonic placenta development [GO:0001892]; endoderm development [GO:0007492]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000785; GO:0000978; GO:0001892; GO:0005634; GO:0005654; GO:0005737; GO:0006338; GO:0006355; GO:0006357; GO:0007420; GO:0007492; GO:0009952; GO:0016589; GO:0035064; GO:0043565; GO:0045944; GO:0046872; GO:0070062; GO:1904949 21359 XM_029358533.2 865 530 475 651 738 Q12830 1.4e-24 Nucleosome-remodeling factor subunit BPTF (Bromodomain and PHD finger-containing transcription factor) (Fetal Alz-50 clone 1 protein) (Fetal Alzheimer antigen) Homo sapiens (Human) anterior/posterior pattern specification [GO:0009952]; brain development [GO:0007420]; chromatin remodeling [GO:0006338]; embryonic placenta development [GO:0001892]; endoderm development [GO:0007492]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000785; GO:0000978; GO:0001892; GO:0005634; GO:0005654; GO:0005737; GO:0006338; GO:0006355; GO:0006357; GO:0007420; GO:0007492; GO:0009952; GO:0016589; GO:0035064; GO:0043565; GO:0045944; GO:0046872; GO:0070062; GO:1904949 21360 XR_006396879.1 25 2 20 24 20 NA NA NA NA NA NA 21361 XM_044322442.1 73 0 0 232 166 NA NA NA NA NA NA 21362 XM_044319243.1 121 170 55 306 72 NA NA NA NA NA NA 21363 XR_003824531.2 23 33 34 39 70 NA NA NA NA NA NA 21364 XM_044309485.1 92 1 51 16 474 NA NA NA NA NA NA 21365 XM_044316510.1 253 69 330 282 406 NA NA NA NA NA NA 21366 XM_044310585.1 0 17 0 0 2 NA NA NA NA NA NA 21367 XM_029336663.2 0 0 12 0 11 NA NA NA NA NA NA 21368 XM_044318963.1 210 24 46 112 0 NA NA NA NA NA NA 21369 XM_044320976.1 783 359 546 886 1184 O15050 0 TPR and ankyrin repeat-containing protein 1 (Lupus brain antigen 1 homolog) Homo sapiens (Human) NA NA 21370 XM_044324886.1 360 367 240 548 351 NA NA NA NA NA NA 21371 XM_029352676.2 3 0 26 7 12 NA NA NA NA NA NA 21372 XM_044312507.1 1253 1369 864 728 796 Q66L33 5.81e-84 Protein MAK16 homolog A (MAK16-like protein A) Xenopus laevis (African clawed frog) NA GO:0005730 21373 XM_044327433.1 77 103 19 37 57 NA NA NA NA NA NA 21374 XM_044314666.1 139 0 37 45 14 NA NA NA NA NA NA 21375 XM_029343759.2 0 37 111 0 25 NA NA NA NA NA NA 21376 XM_029345404.2 98 110 101 129 243 B3TP03 1.02e-84 Cationic amino acid transporter 2 (CAT-2) (CAT2) (cCAT-2) (Low affinity cationic amino acid transporter 2) (Solute carrier family 7 member 2) Gallus gallus (Chicken) amino acid transport [GO:0006865]; L-arginine import across plasma membrane [GO:0097638]; L-lysine import across plasma membrane [GO:0097639]; L-ornithine transmembrane transport [GO:1903352] GO:0000064; GO:0005737; GO:0005794; GO:0005886; GO:0006865; GO:0015171; GO:0015189; GO:0031410; GO:0061459; GO:0097638; GO:0097639; GO:1903352 21377 XM_044324356.1 589 408 377 531 688 Q8C1D8 3.93e-87 Protein IWS1 homolog (IWS1-like protein) Mus musculus (Mouse) mRNA processing [GO:0006397]; poly(A)+ mRNA export from nucleus [GO:0016973]; regulation of histone H3-K36 trimethylation [GO:2001253]; regulation of histone H4 acetylation [GO:0090239]; regulation of mRNA export from nucleus [GO:0010793]; regulation of mRNA processing [GO:0050684]; RNA splicing [GO:0008380] GO:0005634; GO:0005654; GO:0006397; GO:0008380; GO:0010793; GO:0016973; GO:0050684; GO:0090239; GO:2001253 21378 XM_044314918.1 46 18 62 1 122 NA NA NA NA NA NA 21379 XM_044319446.1 35 0 0 0 6 NA NA NA NA NA NA 21380 XM_029326421.2 31253 38107 14164 30805 16036 Q8ISP0 3.51e-87 40S ribosomal protein S18 Branchiostoma belcheri (Amphioxus) translation [GO:0006412] GO:0003735; GO:0005737; GO:0005840; GO:0006412; GO:0019843; GO:1990904 21381 XM_044307860.1 0 0 0 27 55 NA NA NA NA NA NA 21382 XM_029337767.2 28 0 59 0 57 Q09299 9.79e-42 Putative RNA-binding protein EEED8.10 Caenorhabditis elegans SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0003723; GO:0019005; GO:0031146 21383 XM_029334450.2 693 740 658 820 725 NA NA NA NA NA NA 21384 XM_044316850.1 0 0 15 9 59 Q5YCC7 3.72e-140 Transmembrane channel-like protein 3 Gallus gallus (Chicken) NA GO:0005886; GO:0008381 21385 XR_006397721.1 32 0 30 41 28 NA NA NA NA NA NA 21386 XM_044321540.1 12 0 7 12 11 NA NA NA NA NA NA 21387 XM_029348842.2 0 0 17 0 29 Q9FWW9 5.71e-62 Flavin-containing monooxygenase FMO GS-OX-like 2 (EC 1.8.-.-) (Flavin-monooxygenase glucosinolate S-oxygenase-like 2) Arabidopsis thaliana (Mouse-ear cress) defense response to fungus [GO:0050832] GO:0004499; GO:0050660; GO:0050661; GO:0050832 21388 XM_029343269.2 670 632 479 870 615 NA NA NA NA NA NA 21389 XM_029349416.2 170 67 0 0 0 NA NA NA NA NA NA 21390 XM_044329250.1 24 0 0 0 0 NA NA NA NA NA NA 21391 XM_044321069.1 2215 1599 1656 2092 2444 Q8WXX0 0 Dynein axonemal heavy chain 7 (Axonemal beta dynein heavy chain 7) (Ciliary dynein heavy chain 7) (Dynein heavy chain-like protein 2) (hDHC2) Homo sapiens (Human) cilium movement [GO:0003341]; cilium-dependent cell motility [GO:0060285]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018] GO:0003341; GO:0003777; GO:0005509; GO:0005524; GO:0005829; GO:0005858; GO:0005874; GO:0005929; GO:0007018; GO:0008569; GO:0030286; GO:0036156; GO:0036159; GO:0045505; GO:0051959; GO:0060285 21392 XM_029327023.2 218 84 282 156 177 NA NA NA NA NA NA 21393 XM_044307742.1 178 42 77 126 65 NA NA NA NA NA NA 21394 XM_044308332.1 188 123 102 439 0 A2A9C3 0 KICSTOR complex protein SZT2 (Seizure threshold 2 protein) (Transcript increased in glutamate resistance) (TIGR) Mus musculus (Mouse) cellular response to amino acid starvation [GO:0034198]; cellular response to glucose starvation [GO:0042149]; central nervous system development [GO:0007417]; corpus callosum morphogenesis [GO:0021540]; negative regulation of TORC1 signaling [GO:1904262]; pigmentation [GO:0043473]; post-embryonic development [GO:0009791]; protein localization to lysosome [GO:0061462]; regulation of superoxide dismutase activity [GO:1901668]; response to nutrient levels [GO:0031667] GO:0005765; GO:0005777; GO:0007417; GO:0009791; GO:0021540; GO:0031667; GO:0034198; GO:0042149; GO:0043473; GO:0061462; GO:0061700; GO:0140007; GO:1901668; GO:1904262; GO:1990130 21395 XM_044308332.1 188 123 102 439 0 A2A9C3 4.46e-91 KICSTOR complex protein SZT2 (Seizure threshold 2 protein) (Transcript increased in glutamate resistance) (TIGR) Mus musculus (Mouse) cellular response to amino acid starvation [GO:0034198]; cellular response to glucose starvation [GO:0042149]; central nervous system development [GO:0007417]; corpus callosum morphogenesis [GO:0021540]; negative regulation of TORC1 signaling [GO:1904262]; pigmentation [GO:0043473]; post-embryonic development [GO:0009791]; protein localization to lysosome [GO:0061462]; regulation of superoxide dismutase activity [GO:1901668]; response to nutrient levels [GO:0031667] GO:0005765; GO:0005777; GO:0007417; GO:0009791; GO:0021540; GO:0031667; GO:0034198; GO:0042149; GO:0043473; GO:0061462; GO:0061700; GO:0140007; GO:1901668; GO:1904262; GO:1990130 21396 XM_044308332.1 188 123 102 439 0 A2A9C3 1.16e-59 KICSTOR complex protein SZT2 (Seizure threshold 2 protein) (Transcript increased in glutamate resistance) (TIGR) Mus musculus (Mouse) cellular response to amino acid starvation [GO:0034198]; cellular response to glucose starvation [GO:0042149]; central nervous system development [GO:0007417]; corpus callosum morphogenesis [GO:0021540]; negative regulation of TORC1 signaling [GO:1904262]; pigmentation [GO:0043473]; post-embryonic development [GO:0009791]; protein localization to lysosome [GO:0061462]; regulation of superoxide dismutase activity [GO:1901668]; response to nutrient levels [GO:0031667] GO:0005765; GO:0005777; GO:0007417; GO:0009791; GO:0021540; GO:0031667; GO:0034198; GO:0042149; GO:0043473; GO:0061462; GO:0061700; GO:0140007; GO:1901668; GO:1904262; GO:1990130 21397 XM_029335583.2 109 310 254 533 200 P34152 0 Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK) Mus musculus (Mouse) angiogenesis [GO:0001525]; axonogenesis [GO:0007409]; blood vessel development [GO:0001568]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular chloride ion homeostasis [GO:0030644]; cellular response to transforming growth factor beta stimulus [GO:0071560]; central nervous system neuron axonogenesis [GO:0021955]; endothelial cell migration [GO:0043542]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; extracellular matrix organization [GO:0030198]; growth hormone receptor signaling pathway [GO:0060396]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; JNK cascade [GO:0007254]; MAPK cascade [GO:0000165]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of organ growth [GO:0046621]; negative regulation of synapse assembly [GO:0051964]; neuron migration [GO:0001764]; nuclear migration [GO:0007097]; organ growth [GO:0035265]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of macrophage proliferation [GO:0120041]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of wound healing [GO:0090303]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell adhesion [GO:0030155]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of epithelial cell migration [GO:0010632]; regulation of focal adhesion assembly [GO:0051893]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of osteoblast differentiation [GO:0045667]; regulation of protein phosphorylation [GO:0001932]; regulation of substrate adhesion-dependent cell spreading [GO:1900024]; signal complex assembly [GO:0007172]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]; vasodilation [GO:0042311] GO:0000165; GO:0000226; GO:0001525; GO:0001568; GO:0001570; GO:0001725; GO:0001764; GO:0001932; GO:0001934; GO:0003779; GO:0004713; GO:0004715; GO:0004725; GO:0005102; GO:0005178; GO:0005524; GO:0005634; GO:0005730; GO:0005737; GO:0005829; GO:0005886; GO:0005925; GO:0005938; GO:0006468; GO:0007097; GO:0007169; GO:0007172; GO:0007173; GO:0007179; GO:0007229; GO:0007254; GO:0007409; GO:0008284; GO:0008360; GO:0008432; GO:0010507; GO:0010613; GO:0010632; GO:0010634; GO:0010718; GO:0010759; GO:0010763; GO:0014068; GO:0014704; GO:0014911; GO:0016323; GO:0016324; GO:0016477; GO:0016604; GO:0018108; GO:0019901; GO:0019902; GO:0019903; GO:0021955; GO:0022408; GO:0030027; GO:0030154; GO:0030155; GO:0030198; GO:0030307; GO:0030335; GO:0030336; GO:0030644; GO:0031234; GO:0033628; GO:0035265; GO:0036064; GO:0038083; GO:0042127; GO:0042169; GO:0042311; GO:0042383; GO:0042802; GO:0043066; GO:0043197; GO:0043231; GO:0043542; GO:0043548; GO:0044877; GO:0045087; GO:0045202; GO:0045667; GO:0045785; GO:0045860; GO:0046621; GO:0046777; GO:0048013; GO:0048471; GO:0048661; GO:0050766; GO:0050771; GO:0050806; GO:0051893; GO:0051897; GO:0051964; GO:0060252; GO:0060396; GO:0071560; GO:0090303; GO:0098794; GO:0098978; GO:0120041; GO:0140677; GO:1900024; GO:1905274; GO:2000060; GO:2000811 21398 XM_029335583.2 109 310 254 533 200 P34152 6.89e-29 Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK) Mus musculus (Mouse) angiogenesis [GO:0001525]; axonogenesis [GO:0007409]; blood vessel development [GO:0001568]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular chloride ion homeostasis [GO:0030644]; cellular response to transforming growth factor beta stimulus [GO:0071560]; central nervous system neuron axonogenesis [GO:0021955]; endothelial cell migration [GO:0043542]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; extracellular matrix organization [GO:0030198]; growth hormone receptor signaling pathway [GO:0060396]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; JNK cascade [GO:0007254]; MAPK cascade [GO:0000165]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of organ growth [GO:0046621]; negative regulation of synapse assembly [GO:0051964]; neuron migration [GO:0001764]; nuclear migration [GO:0007097]; organ growth [GO:0035265]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of macrophage proliferation [GO:0120041]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of wound healing [GO:0090303]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell adhesion [GO:0030155]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of epithelial cell migration [GO:0010632]; regulation of focal adhesion assembly [GO:0051893]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of osteoblast differentiation [GO:0045667]; regulation of protein phosphorylation [GO:0001932]; regulation of substrate adhesion-dependent cell spreading [GO:1900024]; signal complex assembly [GO:0007172]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]; vasodilation [GO:0042311] GO:0000165; GO:0000226; GO:0001525; GO:0001568; GO:0001570; GO:0001725; GO:0001764; GO:0001932; GO:0001934; GO:0003779; GO:0004713; GO:0004715; GO:0004725; GO:0005102; GO:0005178; GO:0005524; GO:0005634; GO:0005730; GO:0005737; GO:0005829; GO:0005886; GO:0005925; GO:0005938; GO:0006468; GO:0007097; GO:0007169; GO:0007172; GO:0007173; GO:0007179; GO:0007229; GO:0007254; GO:0007409; GO:0008284; GO:0008360; GO:0008432; GO:0010507; GO:0010613; GO:0010632; GO:0010634; GO:0010718; GO:0010759; GO:0010763; GO:0014068; GO:0014704; GO:0014911; GO:0016323; GO:0016324; GO:0016477; GO:0016604; GO:0018108; GO:0019901; GO:0019902; GO:0019903; GO:0021955; GO:0022408; GO:0030027; GO:0030154; GO:0030155; GO:0030198; GO:0030307; GO:0030335; GO:0030336; GO:0030644; GO:0031234; GO:0033628; GO:0035265; GO:0036064; GO:0038083; GO:0042127; GO:0042169; GO:0042311; GO:0042383; GO:0042802; GO:0043066; GO:0043197; GO:0043231; GO:0043542; GO:0043548; GO:0044877; GO:0045087; GO:0045202; GO:0045667; GO:0045785; GO:0045860; GO:0046621; GO:0046777; GO:0048013; GO:0048471; GO:0048661; GO:0050766; GO:0050771; GO:0050806; GO:0051893; GO:0051897; GO:0051964; GO:0060252; GO:0060396; GO:0071560; GO:0090303; GO:0098794; GO:0098978; GO:0120041; GO:0140677; GO:1900024; GO:1905274; GO:2000060; GO:2000811 21399 XM_044326392.1 27 38 45 9 51 NA NA NA NA NA NA 21400 XM_029348433.2 1 43 10 8 36 NA NA NA NA NA NA 21401 XM_044308358.1 93 21 30 56 120 NA NA NA NA NA NA 21402 XM_029350030.2 42 68 62 23 94 Q3L254 3.3e-107 Protein Wnt-7b Gallus gallus (Chicken) canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; lens fiber cell development [GO:0070307]; neuron differentiation [GO:0030182]; positive regulation of JNK cascade [GO:0046330] GO:0005109; GO:0005125; GO:0005615; GO:0030182; GO:0045165; GO:0046330; GO:0060070; GO:0070307 21403 XM_044309102.1 793 1011 498 1269 1533 NA NA NA NA NA NA 21404 XM_044323836.1 0 0 8 5 0 NA NA NA NA NA NA 21405 XM_029327155.2 11 33 11 44 11 Q9GV16 0 Endoglycoceramidase (EGCase) (EC 3.2.1.123) (Glycosphingolipid-specific enzyme) (GSL-specific enzyme) Cyanea nozakii (Jellyfish) carbohydrate derivative catabolic process [GO:1901136]; cellulose catabolic process [GO:0030245]; lipid catabolic process [GO:0016042] GO:0005576; GO:0016042; GO:0030245; GO:0042151; GO:0047876; GO:1901136 21406 XR_006397365.1 8 3 16 4 26 NA NA NA NA NA NA 21407 XM_044314721.1 13 0 0 81 372 Q91VS8 4.43e-154 FERM, ARHGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR) (FERM, RhoGEF and pleckstrin domain-containing protein 2) Mus musculus (Mouse) actin cytoskeleton reorganization [GO:0031532]; cell adhesion [GO:0007155]; hair cycle process [GO:0022405]; neuron remodeling [GO:0016322]; osteoclast differentiation [GO:0030316]; podosome assembly [GO:0071800]; Rac protein signal transduction [GO:0016601]; regulation of integrin activation [GO:0033623]; semaphorin-plexin signaling pathway [GO:0071526] GO:0005085; GO:0005737; GO:0005829; GO:0005856; GO:0007155; GO:0008092; GO:0016322; GO:0016601; GO:0022405; GO:0030316; GO:0031532; GO:0033623; GO:0071526; GO:0071800 21408 XM_029338508.2 1306 728 629 1219 1256 E9Q4N7 2.92e-78 AT-rich interactive domain-containing protein 1B (ARID domain-containing protein 1B) (BRG1-associated factor 250b) (BAF250B) Mus musculus (Mouse) chromatin remodeling [GO:0006338]; dendritic cell dendrite assembly [GO:0097026]; dendritic spine development [GO:0060996]; neuron-neuron synaptic transmission [GO:0007270]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0003677; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0006338; GO:0006357; GO:0007270; GO:0016514; GO:0035060; GO:0045202; GO:0045893; GO:0060996; GO:0071565; GO:0097026 21409 XM_029338508.2 1306 728 629 1219 1256 E9Q4N7 3.09e-30 AT-rich interactive domain-containing protein 1B (ARID domain-containing protein 1B) (BRG1-associated factor 250b) (BAF250B) Mus musculus (Mouse) chromatin remodeling [GO:0006338]; dendritic cell dendrite assembly [GO:0097026]; dendritic spine development [GO:0060996]; neuron-neuron synaptic transmission [GO:0007270]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0003677; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0006338; GO:0006357; GO:0007270; GO:0016514; GO:0035060; GO:0045202; GO:0045893; GO:0060996; GO:0071565; GO:0097026 21410 XM_044317451.1 131 103 62 64 111 Q9W6G7 1.19e-40 DNA polymerase subunit gamma-2, mitochondrial (Mitochondrial DNA polymerase accessory subunit) (MtPolB) (PolG-beta) Xenopus laevis (African clawed frog) mitochondrial DNA replication [GO:0006264] GO:0003677; GO:0005759; GO:0005760; GO:0006264 21411 XM_029346247.2 0 0 8 62 2 Q5ZI57 1.53e-97 Trafficking protein particle complex subunit 3 Gallus gallus (Chicken) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891] GO:0005783; GO:0005829; GO:0006888; GO:0006891; GO:0030008; GO:0033106 21412 XM_044315521.1 12 9 18 0 70 P0CT39 3.48e-76 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 21413 XM_044315782.1 6 0 19 4 32 NA NA NA NA NA NA 21414 XM_044327347.1 29 0 17 0 33 Q09575 1.63e-41 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 21415 XR_006395782.1 108 155 54 92 134 NA NA NA NA NA NA 21416 XM_029339928.2 1652 553 1023 945 814 Q5T5Y3 1.85e-48 Calmodulin-regulated spectrin-associated protein 1 Homo sapiens (Human) cytoplasmic microtubule organization [GO:0031122]; cytoskeleton organization [GO:0007010]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of microtubule depolymerization [GO:0007026]; neuron projection development [GO:0031175]; regulation of cell morphogenesis [GO:0022604]; regulation of microtubule polymerization [GO:0031113] GO:0000226; GO:0005516; GO:0005737; GO:0005874; GO:0007010; GO:0007026; GO:0008017; GO:0022604; GO:0030507; GO:0031113; GO:0031122; GO:0031175; GO:0051011 21417 XM_029339928.2 1652 553 1023 945 814 Q5T5Y3 2.52e-32 Calmodulin-regulated spectrin-associated protein 1 Homo sapiens (Human) cytoplasmic microtubule organization [GO:0031122]; cytoskeleton organization [GO:0007010]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of microtubule depolymerization [GO:0007026]; neuron projection development [GO:0031175]; regulation of cell morphogenesis [GO:0022604]; regulation of microtubule polymerization [GO:0031113] GO:0000226; GO:0005516; GO:0005737; GO:0005874; GO:0007010; GO:0007026; GO:0008017; GO:0022604; GO:0030507; GO:0031113; GO:0031122; GO:0031175; GO:0051011 21418 XM_029347346.2 14 0 1 37 10 C0H690 5.31e-39 Small cysteine-rich protein 1 (Amil-SCRiP1) (SCRiP1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0042151; GO:0090729 21419 XM_029343946.2 57 32 62 73 178 Q96MG7 9.97e-37 Non-structural maintenance of chromosomes element 3 homolog (Non-SMC element 3 homolog) (Hepatocellular carcinoma-associated protein 4) (MAGE-G1 antigen) (Melanoma-associated antigen G1) (Necdin-like protein 2) Homo sapiens (Human) cellular response to hydroxyurea [GO:0072711]; cellular response to radiation [GO:0071478]; cellular response to UV [GO:0034644]; DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of protein ubiquitination [GO:0031398]; protein sumoylation [GO:0016925]; regulation of telomere maintenance [GO:0032204] GO:0000122; GO:0000724; GO:0000781; GO:0005634; GO:0005654; GO:0005737; GO:0006281; GO:0016925; GO:0030915; GO:0031398; GO:0032204; GO:0034644; GO:0046983; GO:0071478; GO:0072711 21420 XM_029324755.2 879 412 274 722 636 Q3UGF1 0 WD repeat-containing protein 19 (Intraflagellar transport 144 homolog) Mus musculus (Mouse) cell morphogenesis [GO:0000902]; ciliary receptor clustering involved in smoothened signaling pathway [GO:0060830]; cilium assembly [GO:0060271]; digestive system development [GO:0055123]; ear morphogenesis [GO:0042471]; embryonic camera-type eye development [GO:0031076]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic limb morphogenesis [GO:0030326]; gonad development [GO:0008406]; in utero embryonic development [GO:0001701]; intraciliary retrograde transport [GO:0035721]; myotome development [GO:0061055]; nervous system process [GO:0050877]; protein localization to ciliary membrane [GO:1903441]; protein localization to cilium [GO:0061512]; protein-containing complex assembly [GO:0065003]; smoothened signaling pathway [GO:0007224]; smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] GO:0000902; GO:0001701; GO:0001750; GO:0005737; GO:0005856; GO:0005929; GO:0007224; GO:0008406; GO:0030326; GO:0030991; GO:0031076; GO:0031514; GO:0032391; GO:0035721; GO:0042471; GO:0048701; GO:0050877; GO:0055123; GO:0060271; GO:0060830; GO:0060831; GO:0061055; GO:0061512; GO:0065003; GO:0097730; GO:1903441 21421 XM_044321156.1 0 0 6 7 0 NA NA NA NA NA NA 21422 XM_044316274.1 0 0 0 0 55 NA NA NA NA NA NA 21423 XR_006392870.1 41 2 25 5 151 NA NA NA NA NA NA 21424 XM_044313318.1 215 184 0 164 2 NA NA NA NA NA NA 21425 XR_006396764.1 29 10 9 14 31 NA NA NA NA NA NA 21426 XM_029345462.2 0 0 0 0 74 Q8N2E2 1.55e-39 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 21427 XM_029345462.2 0 0 0 0 74 Q8N2E2 9.37e-38 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 21428 XM_029345462.2 0 0 0 0 74 Q8N2E2 1.66e-36 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 21429 XM_029345462.2 0 0 0 0 74 Q8N2E2 5.21e-35 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 21430 XM_029345462.2 0 0 0 0 74 Q8N2E2 6.13e-32 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 21431 XM_029345462.2 0 0 0 0 74 Q8N2E2 4.47e-25 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 21432 XM_044308427.1 159 0 18 122 0 A5PJG7 1.63e-77 Holocytochrome c-type synthase (EC 4.4.1.17) (Cytochrome c-type heme lyase) (CCHL) Bos taurus (Bovine) cytochrome c-heme linkage [GO:0018063] GO:0004408; GO:0005739; GO:0005743; GO:0018063; GO:0020037; GO:0046872 21433 XR_006396950.1 57 52 55 71 53 NA NA NA NA NA NA 21434 XM_044322034.1 0 0 8 0 40 NA NA NA NA NA NA 21435 XM_029346351.2 212 133 124 193 40 NA NA NA NA NA NA 21436 XM_029326069.2 12 32 15 0 3 NA NA NA NA NA NA 21437 XM_044323779.1 57 1 11 47 28 Q8N0Z2 1.39e-28 Actin-binding Rho-activating protein (Striated muscle activator of Rho-dependent signaling) (STARS) Homo sapiens (Human) positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein import into nucleus [GO:0006606]; transcription by RNA polymerase II [GO:0006366] GO:0003779; GO:0005886; GO:0006366; GO:0006606; GO:0015629; GO:0030017; GO:0035025; GO:0045944; GO:0051091 21438 XM_029335636.2 705 558 748 806 489 Q8BKD6 1.45e-64 E3 ubiquitin-protein ligase RNF144B (EC 2.3.2.31) (IBR domain-containing protein 2) (RING finger protein 144B) Mus musculus (Mouse) apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000151; GO:0000209; GO:0004842; GO:0005737; GO:0006511; GO:0006915; GO:0031624; GO:0031966; GO:0032436; GO:0043066; GO:0046872; GO:0061630 21439 XM_044326607.1 64 0 25 0 88 O18276 2.68e-59 Gamma-aminobutyric acid receptor subunit beta (GABA(A) receptor subunit beta) Caenorhabditis elegans chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165] GO:0004890; GO:0005230; GO:0005231; GO:0005254; GO:0005886; GO:0006811; GO:0007165; GO:0007268; GO:0030594; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:1902476; GO:1902711; GO:1904315 21440 XM_044310863.1 19 6 0 3 8 NA NA NA NA NA NA 21441 XM_029331878.2 518 1201 651 1053 933 NA NA NA NA NA NA 21442 XM_044308691.1 0 0 0 27 85 NA NA NA NA NA NA 21443 XM_029357366.2 149 85 73 76 126 Q5EBP3 1.43e-29 Armadillo repeat-containing protein 5 Mus musculus (Mouse) adrenal cortex development [GO:0035801]; anatomical structure morphogenesis [GO:0009653]; CD4-positive, alpha-beta T cell differentiation [GO:0043367]; defense response to virus [GO:0051607]; gastrulation [GO:0007369]; hemopoiesis [GO:0030097]; in utero embryonic development [GO:0001701]; mesoderm formation [GO:0001707]; regulation of steroid biosynthetic process [GO:0050810]; T cell proliferation [GO:0042098] GO:0001701; GO:0001707; GO:0005654; GO:0005737; GO:0005829; GO:0005925; GO:0007369; GO:0009653; GO:0016020; GO:0030097; GO:0035801; GO:0042098; GO:0043367; GO:0050810; GO:0051607 21444 XM_029332099.2 33 62 31 26 77 NA NA NA NA NA NA 21445 XR_006392670.1 367 511 263 564 577 Q9NR20 0 Dual specificity tyrosine-phosphorylation-regulated kinase 4 (EC 2.7.12.1) Homo sapiens (Human) peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107] GO:0004674; GO:0004712; GO:0004713; GO:0005524; GO:0005634; GO:0005737; GO:0005856; GO:0018105; GO:0018107; GO:0043231; GO:0046872; GO:0106310 21446 XM_029343535.2 918 494 192 542 535 A1A5F2 0 HEAT repeat-containing protein 5B Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) protein transport [GO:0015031] GO:0015031; GO:0030136 21447 XM_029351477.2 366 67 441 134 1516 NA NA NA NA NA NA 21448 XM_029325641.2 0 1 4 24 22 NA NA NA NA NA NA 21449 XM_044325171.1 8 1 0 9 16 NA NA NA NA NA NA 21450 XM_044322749.1 0 0 28 20 53 Q9NZJ4 0 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 21451 XM_044322749.1 0 0 28 20 53 Q9NZJ4 2.64e-52 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 21452 XM_044322749.1 0 0 28 20 53 Q9NZJ4 6.5e-40 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 21453 XM_044329245.1 361 147 0 195 198 P50748 0 Kinetochore-associated protein 1 (Rough deal homolog) (HsROD) (Rod) (hRod) Homo sapiens (Human) cell division [GO:0051301]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint signaling [GO:0007094]; protein localization to kinetochore involved in kinetochore assembly [GO:1903394]; protein-containing complex assembly [GO:0065003]; regulation of exit from mitosis [GO:0007096] GO:0000070; GO:0000922; GO:0005634; GO:0005737; GO:0005828; GO:0005829; GO:0005886; GO:0007094; GO:0007096; GO:0015629; GO:0031267; GO:0051301; GO:0065003; GO:1903394; GO:1990423 21454 XM_029350033.2 1149 277 210 762 651 NA NA NA NA NA NA 21455 XM_044314983.1 0 1 8 0 32 NA NA NA NA NA NA 21456 XR_006393136.1 154 0 98 73 77 NA NA NA NA NA NA 21457 XM_029350663.2 1077 568 563 997 863 A0A096X8J7 0 NA NA NA NA 21458 XM_044319836.1 4946 3808 2604 5546 3965 Q5VZK9 0 F-actin-uncapping protein LRRC16A (CARMIL homolog) (Capping protein regulator and myosin 1 linker protein 1) (Capping protein, Arp2/3 and myosin-I linker homolog 1) (Capping protein, Arp2/3 and myosin-I linker protein 1) (Leucine-rich repeat-containing protein 16A) Homo sapiens (Human) actin filament network formation [GO:0051639]; actin filament organization [GO:0007015]; barbed-end actin filament uncapping [GO:0051638]; cell migration [GO:0016477]; lamellipodium assembly [GO:0030032]; macropinocytosis [GO:0044351]; negative regulation of barbed-end actin filament capping [GO:2000813]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell migration [GO:0030335]; positive regulation of lamellipodium organization [GO:1902745]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Arp2/3 complex-mediated actin nucleation [GO:0034315]; ruffle organization [GO:0031529]; urate metabolic process [GO:0046415] GO:0005654; GO:0005829; GO:0005886; GO:0007015; GO:0016477; GO:0016607; GO:0030027; GO:0030032; GO:0030335; GO:0030838; GO:0031252; GO:0031529; GO:0031941; GO:0034315; GO:0044351; GO:0044354; GO:0044877; GO:0046415; GO:0051496; GO:0051638; GO:0051639; GO:0070062; GO:1900026; GO:1902745; GO:2000249; GO:2000813 21459 XM_044319339.1 5 0 5 5 10 NA NA NA NA NA NA 21460 XM_044312954.1 0 247 55 0 159 Q9NZM1 0 Myoferlin (Fer-1-like protein 3) Homo sapiens (Human) blood circulation [GO:0008015]; membrane fusion [GO:0061025]; muscle contraction [GO:0006936]; plasma membrane organization [GO:0007009]; plasma membrane repair [GO:0001778]; T-tubule organization [GO:0033292] GO:0001778; GO:0005543; GO:0005635; GO:0005886; GO:0005901; GO:0006936; GO:0007009; GO:0008015; GO:0030659; GO:0031410; GO:0031965; GO:0033292; GO:0043231; GO:0046872; GO:0061025; GO:0070062 21461 XM_029335852.2 47 135 55 13 0 Q75V66 0 Anoctamin-5 (Gnathodiaphyseal dysplasia 1 protein) (Transmembrane protein 16E) Homo sapiens (Human) chloride transmembrane transport [GO:1902476]; chloride transport [GO:0006821]; ion transmembrane transport [GO:0034220]; transmembrane transport [GO:0055085] GO:0005229; GO:0005254; GO:0005789; GO:0005886; GO:0006821; GO:0031982; GO:0034220; GO:0046983; GO:0055085; GO:1902476 21462 XM_044315722.1 2557 51 409 854 384 NA NA NA NA NA NA 21463 XM_029332594.2 221 142 121 106 137 NA NA NA NA NA NA 21464 XM_044316879.1 5 5 16 49 0 Q9Z0U4 2.14e-117 Gamma-aminobutyric acid type B receptor subunit 1 (GABA-B receptor 1) (GABA-B-R1) (GABA-BR1) (GABABR1) (Gb1) Rattus norvegicus (Rat) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; chemical synaptic transmission [GO:0007268]; chemical synaptic transmission, postsynaptic [GO:0099565]; G protein-coupled receptor signaling pathway [GO:0007186]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of dopamine secretion [GO:0033602]; negative regulation of epinephrine secretion [GO:0032811]; negative regulation of gamma-aminobutyric acid secretion [GO:0014053]; negative regulation of synaptic transmission [GO:0050805]; neuron-glial cell signaling [GO:0150099]; osteoblast differentiation [GO:0001649]; positive regulation of glutamate secretion [GO:0014049]; positive regulation of growth hormone secretion [GO:0060124]; regulation of glutamate secretion [GO:0014048]; regulation of postsynaptic membrane potential [GO:0060078]; response to ethanol [GO:0045471]; response to nicotine [GO:0035094]; synaptic transmission, GABAergic [GO:0051932] GO:0001649; GO:0004888; GO:0004965; GO:0005615; GO:0005737; GO:0005789; GO:0005886; GO:0007186; GO:0007193; GO:0007194; GO:0007214; GO:0007268; GO:0008021; GO:0008285; GO:0014048; GO:0014049; GO:0014053; GO:0016020; GO:0030673; GO:0031966; GO:0032811; GO:0033602; GO:0035094; GO:0038037; GO:0038039; GO:0042734; GO:0043005; GO:0043025; GO:0043197; GO:0043198; GO:0043204; GO:0043231; GO:0045121; GO:0045211; GO:0045471; GO:0046982; GO:0050805; GO:0051932; GO:0060078; GO:0060124; GO:0097060; GO:0098685; GO:0098793; GO:0098978; GO:0098982; GO:0099565; GO:0099579; GO:0150047; GO:0150099; GO:1902710; GO:1902712; GO:1990430 21465 XM_029334959.2 8 8 13 33 4 Q6NZQ0 2.47e-44 Cilia- and flagella-associated protein 119 (Coiled-coil domain-containing protein 189) Mus musculus (Mouse) NA GO:0001669; GO:0005737; GO:0097228 21466 XM_029327330.2 2292 1942 991 1871 2104 O00505 0 Importin subunit alpha-4 (Importin alpha Q2) (Qip2) (Karyopherin subunit alpha-3) (SRP1-gamma) Homo sapiens (Human) NLS-bearing protein import into nucleus [GO:0006607]; protein import into nucleus [GO:0006606]; protein-containing complex assembly [GO:0065003]; viral entry into host cell [GO:0046718]; viral penetration into host nucleus [GO:0075732] GO:0005634; GO:0005643; GO:0005654; GO:0005829; GO:0006606; GO:0006607; GO:0008022; GO:0008139; GO:0042564; GO:0043657; GO:0046718; GO:0061608; GO:0065003; GO:0075732 21467 XM_029352978.2 375 149 13 185 148 P35295 9.39e-39 Ras-related protein Rab-20 Mus musculus (Mouse) cellular response to type II interferon [GO:0071346]; intracellular protein transport [GO:0006886]; phagosome acidification [GO:0090383]; phagosome-lysosome fusion [GO:0090385] GO:0003924; GO:0005525; GO:0005794; GO:0006886; GO:0012505; GO:0030670; GO:0043231; GO:0045335; GO:0071346; GO:0090383; GO:0090385 21468 XM_044318468.1 53 0 0 0 0 A9ZSY3 1.61e-87 Facilitated trehalose transporter Tret1 (BmTRET1) Bombyx mori (Silk moth) trehalose transport [GO:0015771] GO:0005886; GO:0015574; GO:0015771; GO:0051119 21469 XM_029330008.2 0 0 18 51 77 Q8IV35 0 WD repeat-containing protein 49 Homo sapiens (Human) NA NA 21470 XM_029344804.2 51 24 60 0 58 Q15119 1.99e-111 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 2) (PDH kinase 2) (PDKII) Homo sapiens (Human) cellular response to nutrient [GO:0031670]; cellular response to reactive oxygen species [GO:0034614]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; insulin receptor signaling pathway [GO:0008286]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; protein phosphorylation [GO:0006468]; regulation of acetyl-CoA biosynthetic process from pyruvate [GO:0010510]; regulation of calcium-mediated signaling [GO:0050848]; regulation of cellular ketone metabolic process [GO:0010565]; regulation of gluconeogenesis [GO:0006111]; regulation of glucose metabolic process [GO:0010906]; regulation of pH [GO:0006885] GO:0004672; GO:0004740; GO:0005524; GO:0005654; GO:0005739; GO:0005759; GO:0005829; GO:0005967; GO:0006006; GO:0006111; GO:0006468; GO:0006885; GO:0008286; GO:0010510; GO:0010565; GO:0010906; GO:0031670; GO:0034614; GO:0042593; GO:0042803; GO:0050848; GO:0072332 21471 XM_029330239.2 3048 3103 1557 2686 2736 Q6XLQ7 6.67e-26 Calumenin Oryctolagus cuniculus (Rabbit) NA GO:0005509; GO:0005576; GO:0005789; GO:0005794; GO:0033018; GO:0042470 21472 XM_044312204.1 7 18 10 41 30 NA NA NA NA NA NA 21473 XM_044328164.1 29 21 18 20 9 NA NA NA NA NA NA 21474 XR_006393552.1 7 5 27 6 101 NA NA NA NA NA NA 21475 XM_029329991.2 20 35 34 67 100 NA NA NA NA NA NA 21476 XM_044315334.1 23 70 67 81 92 NA NA NA NA NA NA 21477 XM_029350541.2 84 90 51 173 40 NA NA NA NA NA NA 21478 XM_029333418.2 0 0 0 86 3 Q8K4G6 3.88e-74 ADP-ribose glycohydrolase MACROD1 (MACRO domain-containing protein 1) (O-acetyl-ADP-ribose deacetylase MACROD1) (EC 3.1.1.106) (Protein LRP16) ([Protein ADP-ribosylaspartate] hydrolase MACROD1) (EC 3.2.2.-) ([Protein ADP-ribosylglutamate] hydrolase MACROD1) (EC 3.2.2.-) Rattus norvegicus (Rat) cellular response to DNA damage stimulus [GO:0006974]; peptidyl-glutamate ADP-deribosylation [GO:0140291]; protein de-ADP-ribosylation [GO:0051725]; purine nucleoside metabolic process [GO:0042278] GO:0005634; GO:0005654; GO:0006974; GO:0016798; GO:0019213; GO:0042278; GO:0051725; GO:0140291; GO:0140293 21479 XM_029356736.2 1686 1951 857 1283 1058 Q28FE2 7.52e-59 Mediator of RNA polymerase II transcription subunit 31 (Mediator complex subunit 31) (Mediator complex subunit soh1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) regulation of DNA-templated transcription [GO:0006355] GO:0003712; GO:0006355; GO:0016592 21480 XM_044310797.1 2994 2611 1691 2393 2852 P47897 0 Glutamine--tRNA ligase (EC 6.1.1.18) (Glutaminyl-tRNA synthetase) (GlnRS) Homo sapiens (Human) brain development [GO:0007420]; glutaminyl-tRNA aminoacylation [GO:0006425]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; tRNA aminoacylation for protein translation [GO:0006418] GO:0004819; GO:0004860; GO:0005524; GO:0005737; GO:0005759; GO:0005829; GO:0006418; GO:0006425; GO:0006469; GO:0007420; GO:0017101; GO:0019901; GO:0032873; GO:0032991; GO:0045892; GO:2001234 21481 XM_029351888.2 1318 497 698 1032 836 NA NA NA NA NA NA 21482 XR_006394275.1 111 110 60 7 19 NA NA NA NA NA NA 21483 XM_044311369.1 4 28 19 128 258 NA NA NA NA NA NA 21484 XM_044313958.1 34 50 29 14 74 NA NA NA NA NA NA 21485 XM_044320190.1 2839 350 72 602 951 Q5AF03 1.43e-29 Glyoxalase 3 (EC 4.2.1.130) (Glutathione-independent glyoxalase) Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243] GO:0005737; GO:0019172; GO:0019243; GO:0030445; GO:0030446; GO:0062040 21486 XM_044318460.1 1303 1218 722 1025 547 Q5RDU7 4.51e-62 Protein yippee-like 5 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cell population proliferation [GO:0008283] GO:0000151; GO:0005634; GO:0005737; GO:0005815; GO:0008283; GO:0030496; GO:0046872; GO:0097431 21487 XM_044316822.1 0 94 56 19 62 NA NA NA NA NA NA 21488 XM_029338084.2 216 196 99 260 362 Q9W770 3.64e-72 Spondin-1 (F-spondin) Gallus gallus (Chicken) cell adhesion [GO:0007155] GO:0005576; GO:0007155; GO:0031012; GO:0046872 21489 XM_029338084.2 216 196 99 260 362 Q9W770 4.27e-21 Spondin-1 (F-spondin) Gallus gallus (Chicken) cell adhesion [GO:0007155] GO:0005576; GO:0007155; GO:0031012; GO:0046872 21490 XM_029345879.2 83 59 23 76 109 NA NA NA NA NA NA 21491 XR_006397458.1 0 10 0 15 40 NA NA NA NA NA NA 21492 XM_029333672.2 1025 881 593 1334 946 Q08CD5 7.33e-116 Ribitol-5-phosphate xylosyltransferase 1 (EC 2.4.2.61) (Transmembrane protein 5) (UDP-D-xylose:ribitol-5-phosphate beta1,4-xylosyltransferase) Danio rerio (Zebrafish) (Brachydanio rerio) protein O-linked mannosylation [GO:0035269] GO:0000139; GO:0005794; GO:0035269; GO:0120053 21493 XM_044308769.1 203 0 0 93 166 Q0KIA2 3.07e-52 PP2C-like domain-containing protein CG9801 Drosophila melanogaster (Fruit fly) NA NA 21494 XM_029344793.2 8 3 15 12 17 NA NA NA NA NA NA 21495 XM_029337618.2 536 522 393 266 282 A5PJU6 2.89e-43 Hydroxylysine kinase (5-hydroxy-L-lysine kinase) (EC 2.7.1.81) (Aminoglycoside phosphotransferase domain-containing protein 1) Bos taurus (Bovine) phosphorylation [GO:0016310] GO:0005737; GO:0016310; GO:0019202; GO:0047992 21496 XM_044312949.1 9 7 24 59 0 NA NA NA NA NA NA 21497 XM_044315482.1 0 0 0 15 21 NA NA NA NA NA NA 21498 XR_006392333.1 18 47 0 0 0 NA NA NA NA NA NA 21499 XM_029334255.2 0 0 0 0 9 P25931 5.26e-34 RYamide receptor (Neuropeptide Y-like receptor) (NPY-R) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218] GO:0001653; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0016020 21500 XM_044314943.1 0 0 91 116 0 NA NA NA NA NA NA 21501 XR_003824451.2 77 62 42 71 26 NA NA NA NA NA NA 21502 XM_044321165.1 3 5 17 3 16 NA NA NA NA NA NA 21503 XM_044310478.1 130 299 107 208 403 NA NA NA NA NA NA 21504 XM_029349585.2 1668 1312 891 1308 1518 Q6ZUI0 2.06e-43 Tumor protein p63-regulated gene 1 protein (Protein FAM79B) Homo sapiens (Human) NA GO:0005737 21505 XM_029337717.2 1130 1032 1040 1552 1465 Q61371 0 Intraflagellar transport protein 88 homolog (Recessive polycystic kidney disease protein Tg737) (Tetratricopeptide repeat protein 10) (TPR repeat protein 10) (TgN(Imorpk)737Rpw) Mus musculus (Mouse) animal organ morphogenesis [GO:0009887]; anterior/posterior pattern specification [GO:0009952]; brain development [GO:0007420]; cardiac muscle cell differentiation [GO:0055007]; cardiac septum morphogenesis [GO:0060411]; cilium assembly [GO:0060271]; cilium movement [GO:0003341]; cochlea development [GO:0090102]; cytoplasmic microtubule organization [GO:0031122]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; endothelial cell morphogenesis [GO:0001886]; epidermal stem cell homeostasis [GO:0036334]; epidermis development [GO:0008544]; eye development [GO:0001654]; forebrain development [GO:0030900]; forebrain morphogenesis [GO:0048853]; heart development [GO:0007507]; heart formation [GO:0060914]; inner ear receptor cell stereocilium organization [GO:0060122]; intraciliary anterograde transport [GO:0035720]; intraciliary transport [GO:0042073]; keratinocyte proliferation [GO:0043616]; kidney development [GO:0001822]; limb development [GO:0060173]; liver development [GO:0001889]; lung development [GO:0030324]; lung vasculature development [GO:0060426]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of keratinocyte proliferation [GO:0010839]; nervous system development [GO:0007399]; neural precursor cell proliferation [GO:0061351]; non-motile cilium assembly [GO:1905515]; Notch signaling pathway [GO:0007219]; pancreas development [GO:0031016]; positive regulation of cilium assembly [GO:0045724]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; primary palate development [GO:1903929]; protein localization [GO:0008104]; regulation of autophagosome assembly [GO:2000785]; regulation of cilium assembly [GO:1902017]; regulation of fat cell differentiation [GO:0045598]; regulation of feeding behavior [GO:0060259]; regulation of odontogenesis of dentin-containing tooth [GO:0042487]; regulation of protein processing [GO:0070613]; response to fluid shear stress [GO:0034405]; smoothened signaling pathway [GO:0007224]; sperm axoneme assembly [GO:0007288]; spermatid nucleus elongation [GO:0007290]; spinal cord dorsal/ventral patterning [GO:0021513]; telencephalon development [GO:0021537] GO:0001654; GO:0001822; GO:0001886; GO:0001889; GO:0002080; GO:0002081; GO:0003341; GO:0005737; GO:0005802; GO:0005813; GO:0005814; GO:0005829; GO:0005929; GO:0005930; GO:0007219; GO:0007224; GO:0007288; GO:0007290; GO:0007368; GO:0007399; GO:0007420; GO:0007507; GO:0008104; GO:0008544; GO:0009887; GO:0009952; GO:0009953; GO:0010839; GO:0019894; GO:0021513; GO:0021537; GO:0030324; GO:0030900; GO:0030992; GO:0031016; GO:0031122; GO:0031514; GO:0032391; GO:0034405; GO:0035720; GO:0036064; GO:0036126; GO:0036334; GO:0042073; GO:0042487; GO:0042733; GO:0043568; GO:0043616; GO:0045598; GO:0045724; GO:0048853; GO:0050680; GO:0055007; GO:0060091; GO:0060122; GO:0060173; GO:0060259; GO:0060271; GO:0060411; GO:0060426; GO:0060914; GO:0061351; GO:0070613; GO:0090102; GO:0097541; GO:0097542; GO:0097546; GO:0097730; GO:1902017; GO:1903929; GO:1905515; GO:2000785 21506 XM_044312043.1 137 30 30 41 116 NA NA NA NA NA NA 21507 XM_029342371.2 65 32 61 98 113 NA NA NA NA NA NA 21508 XM_044324685.1 780 426 225 672 467 Q5E9M5 3.99e-75 snRNA-activating protein complex subunit 3 (SNAPc subunit 3) (Small nuclear RNA-activating complex polypeptide 3) Bos taurus (Bovine) snRNA transcription by RNA polymerase II [GO:0042795]; snRNA transcription by RNA polymerase III [GO:0042796] GO:0001006; GO:0003681; GO:0005634; GO:0019185; GO:0042795; GO:0042796 21509 XM_044314555.1 84 4 2 0 4 NA NA NA NA NA NA 21510 XM_044320727.1 3 0 0 58 1 NA NA NA NA NA NA 21511 XM_029346921.2 73 81 22 60 16 P28606 7.31e-87 Uncharacterized protein SYNPCC7002_A1628 Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (Agmenellum quadruplicatum) histone deacetylation [GO:0016575] GO:0004407; GO:0016575 21512 XM_029335663.2 171 148 126 159 132 NA NA NA NA NA NA 21513 XM_029331313.2 13 13 44 94 200 P22770 5.54e-104 Neuronal acetylcholine receptor subunit alpha-7 Gallus gallus (Chicken) calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; cognition [GO:0050890]; membrane depolarization [GO:0051899]; negative regulation of tumor necrosis factor production [GO:0032720]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAPK cascade [GO:0043410]; regulation of nitric oxide metabolic process [GO:0080164]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; signal transduction [GO:0007165] GO:0001540; GO:0001666; GO:0005737; GO:0005886; GO:0005892; GO:0006816; GO:0006874; GO:0007165; GO:0008284; GO:0015464; GO:0015643; GO:0017081; GO:0022848; GO:0030424; GO:0030425; GO:0032720; GO:0035094; GO:0042166; GO:0042803; GO:0043204; GO:0043410; GO:0045211; GO:0045766; GO:0050890; GO:0051899; GO:0080164 21514 XM_044323915.1 148 154 95 380 45 Q91X17 1.51e-38 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Mus musculus (Mouse) antibacterial innate immune response [GO:0140367]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; autophagy [GO:0006914]; calcium ion homeostasis [GO:0055074]; cellular calcium ion homeostasis [GO:0006874]; cellular chloride ion homeostasis [GO:0030644]; cellular phosphate ion homeostasis [GO:0030643]; cellular response to unfolded protein [GO:0034620]; cellular sodium ion homeostasis [GO:0006883]; chaperone-mediated protein folding [GO:0061077]; chemical homeostasis [GO:0048878]; chloride ion homeostasis [GO:0055064]; citric acid secretion [GO:0046720]; collecting duct development [GO:0072044]; connective tissue replacement [GO:0097709]; creatinine homeostasis [GO:0097273]; defense response to Gram-negative bacterium [GO:0050829]; endoplasmic reticulum organization [GO:0007029]; gene expression [GO:0010467]; glomerular filtration [GO:0003094]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; ion homeostasis [GO:0050801]; juxtaglomerular apparatus development [GO:0072051]; kidney development [GO:0001822]; leukocyte cell-cell adhesion [GO:0007159]; lipid metabolic process [GO:0006629]; loop of Henle development [GO:0072070]; metanephric ascending thin limb development [GO:0072218]; metanephric distal convoluted tubule development [GO:0072221]; metanephric thick ascending limb development [GO:0072233]; micturition [GO:0060073]; multicellular organismal homeostasis [GO:0048871]; multicellular organismal response to stress [GO:0033555]; neutrophil migration [GO:1990266]; organ or tissue specific immune response [GO:0002251]; peptidyl-threonine phosphorylation [GO:0018107]; phosphate ion homeostasis [GO:0055062]; potassium ion homeostasis [GO:0055075]; protein localization to vacuole [GO:0072665]; protein phosphorylation [GO:0006468]; protein transport into plasma membrane raft [GO:0044861]; regulation of blood pressure [GO:0008217]; regulation of protein transport [GO:0051223]; regulation of urine volume [GO:0035809]; renal sodium ion absorption [GO:0070294]; renal urate salt excretion [GO:0097744]; renal water homeostasis [GO:0003091]; response to endoplasmic reticulum stress [GO:0034976]; response to lipopolysaccharide [GO:0032496]; response to unfolded protein [GO:0006986]; response to water deprivation [GO:0009414]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; sodium ion homeostasis [GO:0055078]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; ubiquitin-dependent ERAD pathway [GO:0030433]; urate transport [GO:0015747]; urea transmembrane transport [GO:0071918]; water homeostasis [GO:0030104] GO:0000922; GO:0001822; GO:0002251; GO:0003091; GO:0003094; GO:0005201; GO:0005509; GO:0005615; GO:0005783; GO:0005794; GO:0005886; GO:0005929; GO:0006468; GO:0006629; GO:0006874; GO:0006883; GO:0006914; GO:0006915; GO:0006954; GO:0006986; GO:0007029; GO:0007157; GO:0007159; GO:0008217; GO:0008380; GO:0009410; GO:0009414; GO:0009986; GO:0010467; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0018107; GO:0019864; GO:0030104; GO:0030433; GO:0030643; GO:0030644; GO:0031410; GO:0032496; GO:0033209; GO:0033555; GO:0034620; GO:0034976; GO:0035809; GO:0044861; GO:0045121; GO:0045177; GO:0046720; GO:0048871; GO:0048878; GO:0050801; GO:0050829; GO:0051223; GO:0055062; GO:0055064; GO:0055074; GO:0055075; GO:0055078; GO:0060073; GO:0060170; GO:0061077; GO:0070294; GO:0071918; GO:0072044; GO:0072051; GO:0072070; GO:0072218; GO:0072221; GO:0072233; GO:0072665; GO:0097190; GO:0097273; GO:0097709; GO:0097744; GO:0140367; GO:1990266 21515 XM_029324808.2 379 77 117 271 141 P98198 0 Phospholipid-transporting ATPase ID (EC 7.6.2.1) (ATPase class I type 8B member 2) (P4-ATPase flippase complex alpha subunit ATP8B2) Homo sapiens (Human) Golgi organization [GO:0007030]; ion transmembrane transport [GO:0034220]; phospholipid translocation [GO:0045332] GO:0000287; GO:0005524; GO:0005730; GO:0005789; GO:0005794; GO:0005802; GO:0005829; GO:0005886; GO:0007030; GO:0016887; GO:0034220; GO:0045332; GO:0090554; GO:0140326; GO:0140345; GO:1990531 21516 XM_044322125.1 0 0 33 0 0 Q6NRS1 5.27e-119 Inhibitor of Bruton tyrosine kinase (IBtk) Xenopus laevis (African clawed frog) NA GO:0005737; GO:0016020 21517 XM_044322125.1 0 0 33 0 0 Q6NRS1 1.41e-75 Inhibitor of Bruton tyrosine kinase (IBtk) Xenopus laevis (African clawed frog) NA GO:0005737; GO:0016020 21518 XR_003826532.2 4 0 3 0 11 NA NA NA NA NA NA 21519 XM_044310677.1 256 142 246 305 112 NA NA NA NA NA NA 21520 XM_044328120.1 520 369 294 409 561 Q9H0A0 0 RNA cytidine acetyltransferase (EC 2.3.1.-) (18S rRNA cytosine acetyltransferase) (N-acetyltransferase 10) (N-acetyltransferase-like protein) (hALP) Homo sapiens (Human) negative regulation of telomere maintenance via telomerase [GO:0032211]; positive regulation of translation [GO:0045727]; protein acetylation [GO:0006473]; regulation of centrosome duplication [GO:0010824]; rRNA acetylation involved in maturation of SSU-rRNA [GO:1904812]; rRNA modification [GO:0000154]; tRNA acetylation [GO:0051391] GO:0000049; GO:0000154; GO:0000781; GO:0003723; GO:0005524; GO:0005634; GO:0005654; GO:0005697; GO:0005730; GO:0006473; GO:0008080; GO:0010824; GO:0016020; GO:0030496; GO:0032211; GO:0045727; GO:0051391; GO:0070182; GO:0106162; GO:1904812; GO:1990883 21521 XM_044325616.1 0 65 0 0 41 Q9NVD3 2.93e-40 SET domain-containing protein 4 (EC 2.1.1.-) (EC 2.1.1.364) Homo sapiens (Human) histone H3-K4 dimethylation [GO:0044648]; histone H3-K4 monomethylation [GO:0097692]; inflammatory response [GO:0006954]; peptidyl-lysine monomethylation [GO:0018026]; peptidyl-lysine trimethylation [GO:0018023]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell proliferation in bone marrow [GO:0071863] GO:0005634; GO:0005829; GO:0006954; GO:0016279; GO:0018023; GO:0018026; GO:0032755; GO:0032760; GO:0042799; GO:0042800; GO:0044648; GO:0050729; GO:0071863; GO:0097692; GO:0140941; GO:0140944; GO:0140945 21522 XM_029357137.2 84 203 158 211 69 NA NA NA NA NA NA 21523 XM_029345113.2 527 885 412 580 528 NA NA NA NA NA NA 21524 XM_044307699.1 10 21 14 7 5 Q8ITC7 1.48e-21 Neuropeptides capa receptor (Cap2b receptor) (Capability receptor) Drosophila melanogaster (Fruit fly) body fluid secretion [GO:0007589]; cellular response to desiccation [GO:0071465]; G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218]; positive regulation of calcium ion transport [GO:0051928] GO:0001607; GO:0004930; GO:0005886; GO:0007186; GO:0007218; GO:0007589; GO:0008188; GO:0016020; GO:0016323; GO:0051928; GO:0071465 21525 XM_044324070.1 41 82 54 33 13 NA NA NA NA NA NA 21526 XM_029340160.2 446 365 198 519 380 Q5SNQ7 4.79e-125 Protein SERAC1 (Serine active site-containing protein 1) Danio rerio (Zebrafish) (Brachydanio rerio) phospholipid biosynthetic process [GO:0008654] GO:0005739; GO:0005783; GO:0008654; GO:0016020 21527 XR_006396313.1 83 7 21 51 51 NA NA NA NA NA NA 21528 XM_044323733.1 0 0 5 0 8 NA NA NA NA NA NA 21529 XM_044318990.1 171 96 63 133 67 NA NA NA NA NA NA 21530 XM_044320097.1 0 0 2 4 19 NA NA NA NA NA NA 21531 XM_029325921.2 32 13 4 32 26 NA NA NA NA NA NA 21532 XR_006395510.1 241 83 75 171 172 NA NA NA NA NA NA 21533 XM_029336066.2 287 480 254 353 283 Q62962 1.38e-53 Acid-sensing ion channel 2 (ASIC2) (Amiloride-sensitive brain sodium channel) (Amiloride-sensitive brain sodium channel 2) (Amiloride-sensitive cation channel 1, neuronal) (Amiloride-sensitive cation channel neuronal 1) (Brain sodium channel 1) (BNC1) (BNaC1) (Mammalian degenerin homolog) (MDEG) Rattus norvegicus (Rat) cation transmembrane transport [GO:0098655]; cation transport [GO:0006812]; cellular response to acidic pH [GO:0071468]; cellular response to xenobiotic stimulus [GO:0071466]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; establishment of localization in cell [GO:0051649]; ion transmembrane transport [GO:0034220]; negative regulation of apoptotic process [GO:0043066]; phototransduction [GO:0007602]; positive regulation of cation channel activity [GO:2001259]; positive regulation of synapse assembly [GO:0051965]; protein localization to synapse [GO:0035418]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback [GO:0003026]; regulation of vasoconstriction [GO:0019229]; response to acidic pH [GO:0010447]; response to mechanical stimulus [GO:0009612]; sensory perception of sound [GO:0007605]; sensory perception of sour taste [GO:0050915]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814]; synapse assembly [GO:0007416] GO:0003026; GO:0005216; GO:0005248; GO:0005261; GO:0005886; GO:0006812; GO:0006814; GO:0007416; GO:0007602; GO:0007605; GO:0009612; GO:0010447; GO:0015280; GO:0016020; GO:0019229; GO:0022839; GO:0034220; GO:0034765; GO:0035418; GO:0035725; GO:0042391; GO:0043005; GO:0043025; GO:0043066; GO:0043197; GO:0045202; GO:0050915; GO:0050974; GO:0051649; GO:0051965; GO:0071466; GO:0071468; GO:0098655; GO:2001259 21534 XR_006392536.1 4 6 1 2 9 Q9M2U3 4.15e-22 Protein ALP1-like (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) NA GO:0000118; GO:0004518; GO:0046872 21535 XR_006392536.1 4 6 1 2 9 Q9M2U3 4.15e-22 Protein ALP1-like (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) NA GO:0000118; GO:0004518; GO:0046872 21536 XM_044317796.1 9 39 6 4 1 NA NA NA NA NA NA 21537 XM_044311819.1 7 1 0 0 0 NA NA NA NA NA NA 21538 XM_044307837.1 202 157 79 134 494 NA NA NA NA NA NA 21539 XR_006396897.1 45 0 0 0 15 NA NA NA NA NA NA 21540 XR_006391274.1 886 240 1282 462 417 NA NA NA NA NA NA 21541 XM_029326282.2 26331 19548 15694 22307 12688 O08585 1.06e-34 Clathrin light chain A (Lca) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; clathrin coat assembly [GO:0048268]; clathrin-dependent endocytosis [GO:0072583]; intracellular protein transport [GO:0006886] GO:0005198; GO:0005819; GO:0005886; GO:0005905; GO:0006886; GO:0007049; GO:0030118; GO:0030125; GO:0030130; GO:0030132; GO:0030136; GO:0030672; GO:0031410; GO:0032050; GO:0042277; GO:0044877; GO:0048268; GO:0051020; GO:0051301; GO:0071439; GO:0072583; GO:0098835; GO:0098843; GO:0098978; GO:0099631 21542 XR_006393118.1 206 123 206 109 184 NA NA NA NA NA NA 21543 XR_006394124.1 211 345 202 27 198 NA NA NA NA NA NA 21544 XM_029340937.2 1544 1495 794 864 973 NA NA NA NA NA NA 21545 XM_029327572.2 538 745 146 1532 668 B8EIZ7 1.32e-168 NA NA NA NA 21546 XM_044319092.1 59 62 76 70 118 Q13507 2.54e-90 Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (TRP-3) (hTrp-3) (hTrp3) Homo sapiens (Human) calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; phototransduction [GO:0007602]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of cardiac muscle hypertrophy in response to stress [GO:1903244]; regulation of cytosolic calcium ion concentration [GO:0051480]; response to ATP [GO:0033198]; response to calcium ion [GO:0051592]; single fertilization [GO:0007338] GO:0005262; GO:0005886; GO:0006816; GO:0007338; GO:0007602; GO:0010524; GO:0015279; GO:0033198; GO:0034703; GO:0046872; GO:0051480; GO:0051592; GO:0070588; GO:0070679; GO:1903244 21547 XM_044311727.1 0 9 6 0 18 NA NA NA NA NA NA 21548 XM_029337711.2 78 168 131 62 149 Q5ZIH9 2.96e-37 Coiled-coil domain-containing protein 174 Gallus gallus (Chicken) NA GO:0005634 21549 XM_029335221.2 2116 1087 1453 2933 2276 Q92051 2.91e-51 Carbonic anhydrase (EC 4.2.1.1) (Carbonate dehydratase) Danio rerio (Zebrafish) (Brachydanio rerio) carbon dioxide transport [GO:0015670]; hypotonic salinity response [GO:0042539]; one-carbon metabolic process [GO:0006730] GO:0004089; GO:0005737; GO:0006730; GO:0008270; GO:0015670; GO:0016836; GO:0042539 21550 XM_029350014.2 309 36 314 170 1326 Q58A42 7.7e-73 Protein DD3-3 Dictyostelium discoideum (Social amoeba) NA GO:0016020 21551 XM_044327929.1 132 80 50 165 148 Q8AV58 1.23e-62 Protein sidekick-1 Gallus gallus (Chicken) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; retina layer formation [GO:0010842]; synapse assembly [GO:0007416] GO:0005886; GO:0007156; GO:0007416; GO:0010842; GO:0042802; GO:0045202 21552 XM_044327929.1 132 80 50 165 148 Q8AV58 1.05e-59 Protein sidekick-1 Gallus gallus (Chicken) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; retina layer formation [GO:0010842]; synapse assembly [GO:0007416] GO:0005886; GO:0007156; GO:0007416; GO:0010842; GO:0042802; GO:0045202 21553 XM_044327929.1 132 80 50 165 148 Q8AV58 6.21e-41 Protein sidekick-1 Gallus gallus (Chicken) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; retina layer formation [GO:0010842]; synapse assembly [GO:0007416] GO:0005886; GO:0007156; GO:0007416; GO:0010842; GO:0042802; GO:0045202 21554 XM_044327929.1 132 80 50 165 148 Q8AV58 9.56e-37 Protein sidekick-1 Gallus gallus (Chicken) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; retina layer formation [GO:0010842]; synapse assembly [GO:0007416] GO:0005886; GO:0007156; GO:0007416; GO:0010842; GO:0042802; GO:0045202 21555 XM_044327929.1 132 80 50 165 148 Q8AV58 3.84e-24 Protein sidekick-1 Gallus gallus (Chicken) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; retina layer formation [GO:0010842]; synapse assembly [GO:0007416] GO:0005886; GO:0007156; GO:0007416; GO:0010842; GO:0042802; GO:0045202 21556 XM_044323340.1 61 13 64 65 42 B8V7S0 5.52e-69 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 21557 XM_029347068.2 48 17 5 0 5 Q64191 2.35e-110 N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase (EC 3.5.1.26) (Aspartylglucosaminidase) (AGA) (Glycosylasparaginase) (N4-(N-acetyl-beta-glucosaminyl)-L-asparagine amidase) [Cleaved into: Glycosylasparaginase alpha chain; Glycosylasparaginase beta chain] Mus musculus (Mouse) protein deglycosylation [GO:0006517]; proteolysis [GO:0006508] GO:0003948; GO:0005615; GO:0005737; GO:0005764; GO:0005783; GO:0006508; GO:0006517; GO:0008233; GO:0043621 21558 XM_029328134.2 0 0 9 1 64 NA NA NA NA NA NA 21559 XR_006396917.1 1 1 0 11 0 NA NA NA NA NA NA 21560 XM_029333315.2 88 23 41 53 40 Q09470 1.09e-83 Potassium voltage-gated channel subfamily A member 1 (Voltage-gated K(+) channel HuKI) (Voltage-gated potassium channel HBK1) (Voltage-gated potassium channel subunit Kv1.1) Homo sapiens (Human) axon development [GO:0061564]; cell communication by electrical coupling [GO:0010644]; cellular response to magnesium ion [GO:0071286]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; corpus callosum development [GO:0022038]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; detection of mechanical stimulus involved in sensory perception of touch [GO:0050976]; hippocampus development [GO:0021766]; magnesium ion homeostasis [GO:0010960]; neuroblast proliferation [GO:0007405]; neuromuscular process [GO:0050905]; neuronal action potential [GO:0019228]; neuronal signal transduction [GO:0023041]; optic nerve development [GO:0021554]; positive regulation of voltage-gated potassium channel activity [GO:1903818]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; protein localization [GO:0008104]; regulation of membrane potential [GO:0042391]; regulation of muscle contraction [GO:0006937]; startle response [GO:0001964] GO:0001964; GO:0005249; GO:0005251; GO:0005267; GO:0005783; GO:0005829; GO:0005886; GO:0006813; GO:0006937; GO:0007268; GO:0007405; GO:0008076; GO:0008104; GO:0009986; GO:0010644; GO:0010960; GO:0015079; GO:0016020; GO:0016324; GO:0019228; GO:0021554; GO:0021766; GO:0021987; GO:0022038; GO:0023041; GO:0030054; GO:0030425; GO:0031410; GO:0033270; GO:0042391; GO:0042734; GO:0043025; GO:0043194; GO:0043204; GO:0043679; GO:0044224; GO:0044305; GO:0045202; GO:0045211; GO:0050905; GO:0050966; GO:0050976; GO:0051260; GO:0061564; GO:0070161; GO:0071286; GO:0071805; GO:0097718; GO:0098978; GO:0099508; GO:1903818; GO:1905030 21561 XM_044316413.1 924 334 351 375 746 Q4V847 2.13e-108 Integrator complex subunit 8 (Int8) Xenopus laevis (African clawed frog) snRNA 3'-end processing [GO:0034472] GO:0005634; GO:0034472 21562 XM_044317771.1 1601 1496 1060 1117 740 Q78JE5 2.39e-27 F-box only protein 22 Mus musculus (Mouse) cellular response to starvation [GO:0009267]; nucleocytoplasmic transport [GO:0006913]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; regulation of myotube differentiation [GO:0010830]; regulation of skeletal muscle fiber development [GO:0048742]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000209; GO:0005634; GO:0005737; GO:0006511; GO:0006913; GO:0009267; GO:0010830; GO:0030018; GO:0032436; GO:0043161; GO:0048742; GO:2000060 21563 XM_029333301.2 702 566 380 525 300 P35280 1.24e-67 Ras-related protein Rab-8A (EC 3.6.5.2) Rattus norvegicus (Rat) autophagy [GO:0006914]; axonogenesis [GO:0007409]; cellular response to insulin stimulus [GO:0032869]; cilium assembly [GO:0060271]; endocytic recycling [GO:0032456]; glucose homeostasis [GO:0042593]; Golgi organization [GO:0007030]; Golgi vesicle fusion to target membrane [GO:0048210]; neurotransmitter receptor transport to postsynaptic membrane [GO:0098969]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; positive regulation of glucose import [GO:0046326]; protein localization to cilium [GO:0061512]; protein localization to plasma membrane [GO:0072659]; protein secretion [GO:0009306]; regulation of autophagy [GO:0010506]; regulation of exocytosis [GO:0017157]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of protein localization [GO:0032880]; regulation of protein transport [GO:0051223]; vesicle docking involved in exocytosis [GO:0006904]; vesicle-mediated transport in synapse [GO:0099003] GO:0003924; GO:0005525; GO:0005768; GO:0005794; GO:0005813; GO:0005814; GO:0005886; GO:0005929; GO:0006904; GO:0006914; GO:0007030; GO:0007409; GO:0008021; GO:0009306; GO:0010506; GO:0014069; GO:0017157; GO:0019003; GO:0019901; GO:0030140; GO:0030425; GO:0030496; GO:0030659; GO:0030670; GO:0031410; GO:0031489; GO:0032456; GO:0032869; GO:0032880; GO:0036064; GO:0042593; GO:0043005; GO:0043025; GO:0043197; GO:0043231; GO:0045202; GO:0045335; GO:0046326; GO:0048169; GO:0048210; GO:0051223; GO:0055037; GO:0055038; GO:0060170; GO:0060271; GO:0061512; GO:0072659; GO:0097546; GO:0097730; GO:0098887; GO:0098969; GO:0098978; GO:0099003; GO:1990782 21564 XR_006398087.1 31 9 51 30 232 NA NA NA NA NA NA 21565 XR_003823845.2 28 28 2 7 20 NA NA NA NA NA NA 21566 XM_029350738.2 253 149 86 124 168 O43909 0 Exostosin-like 3 (EC 2.4.1.223) (EXT-related protein 1) (Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Hereditary multiple exostoses gene isolog) (Multiple exostosis-like protein 3) (Putative tumor suppressor protein EXTL3) Homo sapiens (Human) heparan sulfate proteoglycan biosynthetic process [GO:0015012]; positive regulation of cell growth [GO:0030307]; protein glycosylation [GO:0006486] GO:0000287; GO:0001888; GO:0005783; GO:0005789; GO:0005794; GO:0006486; GO:0015012; GO:0016757; GO:0030307 21567 XM_044323774.1 0 0 0 10 2 NA NA NA NA NA NA 21568 XM_029353336.2 19 0 0 0 17 NA NA NA NA NA NA 21569 XM_044322407.1 961 848 496 873 1111 NA NA NA NA NA NA 21570 XM_044319930.1 907 906 434 500 1024 Q7ZU29 0 Nuclear pore complex protein Nup93 (93 kDa nucleoporin) (Dead eye protein) (Nucleoporin Nup93) Danio rerio (Zebrafish) (Brachydanio rerio) nuclear pore complex assembly [GO:0051292]; poly(A)+ mRNA export from nucleus [GO:0016973]; protein import into nucleus [GO:0006606] GO:0005643; GO:0006606; GO:0016973; GO:0017056; GO:0031965; GO:0034399; GO:0051292 21571 XM_029347464.2 258 125 112 227 107 NA NA NA NA NA NA 21572 XR_003824133.2 69 21 30 57 37 NA NA NA NA NA NA 21573 XM_029328014.2 1330 152 936 663 299 Q2TB18 2.22e-70 Protein asteroid homolog 1 Homo sapiens (Human) NA GO:0004518 21574 XM_029340337.2 312 1024 346 721 702 NA NA NA NA NA NA 21575 XR_006394068.1 489 360 175 234 111 NA NA NA NA NA NA 21576 XM_044310250.1 1 1 16 0 141 NA NA NA NA NA NA 21577 XR_006394973.1 23 13 41 42 54 NA NA NA NA NA NA 21578 XR_006394353.1 0 10 1 0 0 NA NA NA NA NA NA 21579 XM_029327201.2 0 10 0 16 21 Q29RU2 5.82e-26 Oncoprotein-induced transcript 3 protein Bos taurus (Bovine) NA GO:0005509; GO:0005635 21580 XR_006397903.1 558 371 312 1048 887 P97739 3.03e-26 Endothelin-converting enzyme 1 (ECE-1) (EC 3.4.24.71) Cavia porcellus (Guinea pig) proteolysis [GO:0006508] GO:0004222; GO:0005886; GO:0006508; GO:0046872 21581 XM_044320082.1 780 664 1223 777 1750 P10079 8.8e-87 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 21582 XM_044320082.1 780 664 1223 777 1750 P10079 1.21e-83 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 21583 XM_044320082.1 780 664 1223 777 1750 P10079 1.93e-81 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 21584 XM_044320082.1 780 664 1223 777 1750 P10079 1.18e-80 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 21585 XM_044320082.1 780 664 1223 777 1750 P10079 5.17e-79 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 21586 XM_044320082.1 780 664 1223 777 1750 P10079 7.81e-78 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 21587 XM_044320082.1 780 664 1223 777 1750 P10079 3.96e-77 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 21588 XM_044320082.1 780 664 1223 777 1750 P10079 7.7e-72 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 21589 XM_044320082.1 780 664 1223 777 1750 P10079 9.88e-47 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 21590 XM_029347273.2 215 177 94 117 278 Q8BX37 6e-169 Acid phosphatase type 7 (EC 3.1.3.2) (Purple acid phosphatase long form) Mus musculus (Mouse) NA GO:0003993; GO:0005576; GO:0046872 21591 XM_044327139.1 13 6 1 3 0 NA NA NA NA NA NA 21592 XM_044326437.1 101 28 18 11 144 NA NA NA NA NA NA 21593 XM_029333209.2 54 47 39 100 654 NA NA NA NA NA NA 21594 XM_029327757.2 107 288 0 64 7 NA NA NA NA NA NA 21595 XR_006395084.1 25 14 32 54 41 NA NA NA NA NA NA 21596 XM_029358749.2 6268 5959 4815 7147 6675 Q95LD9 6.7e-68 Aryl hydrocarbon receptor (Ah receptor) (AhR) Delphinapterus leucas (Beluga whale) cAMP-mediated signaling [GO:0019933]; cell cycle [GO:0007049]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; circadian regulation of gene expression [GO:0032922]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of T cell mediated immune response to tumor cell [GO:0002841]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of adaptive immune response [GO:0002819]; regulation of B cell proliferation [GO:0030888]; response to toxic substance [GO:0009636]; response to xenobiotic stimulus [GO:0009410] GO:0001094; GO:0001223; GO:0002819; GO:0002841; GO:0004879; GO:0005634; GO:0005737; GO:0005829; GO:0007049; GO:0009410; GO:0009636; GO:0017025; GO:0019933; GO:0030888; GO:0032922; GO:0034753; GO:0045892; GO:0045893; GO:0045944; GO:0046982; GO:0051879; GO:0060090; GO:0061629; GO:0070888; GO:0071320; GO:1904322; GO:1904613; GO:1990837 21597 XM_029324090.2 1041 512 575 800 363 P15314 3.24e-27 Interferon regulatory factor 1 (IRF-1) Mus musculus (Mouse) apoptotic process [GO:0006915]; CD8-positive, alpha-beta T cell differentiation [GO:0043374]; cellular response to interferon-beta [GO:0035458]; cellular response to interleukin-1 [GO:0071347]; cellular response to mechanical stimulus [GO:0071260]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to tumor necrosis factor [GO:0071356]; defense response to virus [GO:0051607]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; immune system process [GO:0002376]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; positive regulation of cell death [GO:0010942]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of natural killer cell differentiation [GO:0032825]; positive regulation of T-helper 1 cell differentiation [GO:0045627]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of adaptive immune response [GO:0002819]; regulation of CD8-positive, alpha-beta T cell proliferation [GO:2000564]; regulation of cell cycle [GO:0051726]; regulation of gene expression [GO:0010468]; regulation of innate immune response [GO:0045088]; regulation of MyD88-dependent toll-like receptor signaling pathway [GO:0034124]; regulation of transcription by RNA polymerase II [GO:0006357]; response to growth hormone [GO:0060416]; transcription by RNA polymerase II [GO:0006366]; type II interferon-mediated signaling pathway [GO:0060333] GO:0000785; GO:0000976; GO:0000977; GO:0000978; GO:0000981; GO:0001228; GO:0002376; GO:0002819; GO:0003677; GO:0003700; GO:0005634; GO:0005737; GO:0006357; GO:0006366; GO:0006915; GO:0007249; GO:0010468; GO:0010942; GO:0032481; GO:0032728; GO:0032735; GO:0032825; GO:0034124; GO:0035458; GO:0042532; GO:0043374; GO:0043565; GO:0045088; GO:0045590; GO:0045627; GO:0045629; GO:0045892; GO:0045893; GO:0045944; GO:0051607; GO:0051726; GO:0060333; GO:0060416; GO:0071260; GO:0071347; GO:0071356; GO:0071375; GO:2000564 21598 XM_029347175.2 369 335 274 316 214 NA NA NA NA NA NA 21599 XR_006394836.1 207 38 122 142 151 NA NA NA NA NA NA 21600 XM_044320340.1 593 264 293 470 533 A1L1C7 0 PAN2-PAN3 deadenylation complex subunit pan3 (PAB1P-dependent poly(A)-specific ribonuclease) (Poly(A)-nuclease deadenylation complex subunit 3) (PAN deadenylation complex subunit 3) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) mRNA processing [GO:0006397]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; positive regulation of cytoplasmic mRNA processing body assembly [GO:0010606]; protein phosphorylation [GO:0006468] GO:0000289; GO:0000932; GO:0003723; GO:0004672; GO:0005524; GO:0006397; GO:0006468; GO:0010606; GO:0031251; GO:0046872 21601 XM_029356021.2 229 67 0 148 206 Q9JHE4 1.03e-54 Galactosylceramide sulfotransferase (GalCer sulfotransferase) (EC 2.8.2.11) (3'-phosphoadenosine-5'-phosphosulfate:GalCer sulfotransferase) (3'-phosphoadenylylsulfate:galactosylceramide 3'-sulfotransferase) (Cerebroside sulfotransferase) Mus musculus (Mouse) galactosylceramide biosynthetic process [GO:0006682]; galactosylceramide metabolic process [GO:0006681]; glycerolipid metabolic process [GO:0046486]; glycolipid biosynthetic process [GO:0009247]; myelination [GO:0042552]; spermatogenesis [GO:0007283]; sphingolipid metabolic process [GO:0006665] GO:0000139; GO:0001733; GO:0006665; GO:0006681; GO:0006682; GO:0007283; GO:0008146; GO:0009247; GO:0016020; GO:0042552; GO:0046486; GO:0050694 21602 XM_044308125.1 744 402 353 983 832 Q8WXX0 0 Dynein axonemal heavy chain 7 (Axonemal beta dynein heavy chain 7) (Ciliary dynein heavy chain 7) (Dynein heavy chain-like protein 2) (hDHC2) Homo sapiens (Human) cilium movement [GO:0003341]; cilium-dependent cell motility [GO:0060285]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018] GO:0003341; GO:0003777; GO:0005509; GO:0005524; GO:0005829; GO:0005858; GO:0005874; GO:0005929; GO:0007018; GO:0008569; GO:0030286; GO:0036156; GO:0036159; GO:0045505; GO:0051959; GO:0060285 21603 XM_029346400.2 23 0 7 22 0 Q8BYM7 1.28e-142 Radial spoke head protein 4 homolog A (Radial spoke head-like protein 3) Mus musculus (Mouse) axoneme assembly [GO:0035082]; cilium movement [GO:0003341]; cilium movement involved in cell motility [GO:0060294]; maintenance of ciliary planar beating movement pattern [GO:0120221]; radial spoke assembly [GO:0062177] GO:0001534; GO:0001535; GO:0003341; GO:0005654; GO:0005730; GO:0005929; GO:0005930; GO:0035082; GO:0060294; GO:0062177; GO:0120221 21604 XM_029350702.2 1394 1256 1106 1253 1034 P63018 0 Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) Rattus norvegicus (Rat) aging [GO:0007568]; ATP metabolic process [GO:0046034]; axo-dendritic transport [GO:0008088]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; cerebellum development [GO:0021549]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein folding [GO:0061077]; clathrin coat disassembly [GO:0072318]; estrous cycle [GO:0044849]; forebrain development [GO:0030900]; G1/S transition of mitotic cell cycle [GO:0000082]; kidney development [GO:0001822]; late endosomal microautophagy [GO:0061738]; maintenance of postsynaptic specialization structure [GO:0098880]; modulation by host of viral process [GO:0044788]; mRNA processing [GO:0006397]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of supramolecular fiber organization [GO:1902904]; positive regulation by host of viral genome replication [GO:0044829]; positive regulation of catalytic activity [GO:0043085]; positive regulation of gene expression [GO:0010628]; positive regulation of lysosomal membrane permeability [GO:0097214]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein refolding [GO:1904592]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein autophosphorylation [GO:0046777]; protein folding [GO:0006457]; protein import into nucleus [GO:0006606]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; protein transmembrane import into intracellular organelle [GO:0044743]; protein-containing complex disassembly [GO:0032984]; regulation of cell cycle [GO:0051726]; regulation of postsynapse organization [GO:0099175]; regulation of protein complex stability [GO:0061635]; regulation of protein stability [GO:0031647]; response to activity [GO:0014823]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to nickel cation [GO:0010045]; response to odorant [GO:1990834]; response to progesterone [GO:0032570]; response to starvation [GO:0042594]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; sensory perception of smell [GO:0007608]; skeletal muscle tissue development [GO:0007519]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192] GO:0000082; GO:0000974; GO:0001664; GO:0001786; GO:0001822; GO:0001916; GO:0001917; GO:0003723; GO:0005102; GO:0005524; GO:0005634; GO:0005681; GO:0005730; GO:0005737; GO:0005764; GO:0005765; GO:0005770; GO:0005776; GO:0005829; GO:0005874; GO:0005882; GO:0005886; GO:0006397; GO:0006457; GO:0006606; GO:0007519; GO:0007568; GO:0007608; GO:0008021; GO:0008088; GO:0008380; GO:0009408; GO:0009410; GO:0009986; GO:0010045; GO:0010628; GO:0010667; GO:0014069; GO:0014823; GO:0016191; GO:0016192; GO:0016887; GO:0019899; GO:0021549; GO:0030424; GO:0030425; GO:0030674; GO:0030900; GO:0031072; GO:0031625; GO:0031647; GO:0031686; GO:0032279; GO:0032355; GO:0032570; GO:0032984; GO:0032991; GO:0034605; GO:0034620; GO:0042026; GO:0042277; GO:0042470; GO:0042594; GO:0043005; GO:0043025; GO:0043085; GO:0043195; GO:0043197; GO:0043198; GO:0043202; GO:0043204; GO:0043531; GO:0044183; GO:0044309; GO:0044743; GO:0044788; GO:0044829; GO:0044849; GO:0045121; GO:0045471; GO:0045862; GO:0045892; GO:0046034; GO:0046777; GO:0048026; GO:0048471; GO:0050766; GO:0051082; GO:0051085; GO:0051087; GO:0051726; GO:0051787; GO:0055131; GO:0061077; GO:0061635; GO:0061684; GO:0061738; GO:0061740; GO:0070062; GO:0071276; GO:0072318; GO:0097214; GO:0098684; GO:0098690; GO:0098793; GO:0098794; GO:0098880; GO:0098978; GO:0099175; GO:0099523; GO:0099524; GO:0099634; GO:0101031; GO:0140545; GO:0140662; GO:1902904; GO:1903206; GO:1904592; GO:1904593; GO:1904764; GO:1990124; GO:1990832; GO:1990833; GO:1990834; GO:1990836; GO:1990904 21605 XM_044309403.1 8 8 16 43 41 NA NA NA NA NA NA 21606 XM_029332973.2 4124 4787 3576 1971 2075 P0DUG2 6.31e-57 Antimicrobial peptide AmAMP1 Acropora millepora (Staghorn coral) (Heteropora millepora) defense response to bacterium [GO:0042742] GO:0005576; GO:0042742 21607 XM_044318511.1 93 67 240 454 293 Q9ULT8 0 E3 ubiquitin-protein ligase HECTD1 (EC 2.3.2.26) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1) Homo sapiens (Human) anatomical structure development [GO:0048856]; aorta development [GO:0035904]; heart valve development [GO:0003170]; natural killer cell differentiation [GO:0001779]; negative regulation of protein localization to plasma membrane [GO:1903077]; neural tube closure [GO:0001843]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein localization to plasma membrane [GO:0072659]; protein polyubiquitination [GO:0000209]; spongiotrophoblast differentiation [GO:0060708]; trophoblast giant cell differentiation [GO:0060707]; ventricular septum development [GO:0003281] GO:0000209; GO:0001779; GO:0001843; GO:0003170; GO:0003281; GO:0016607; GO:0032436; GO:0035904; GO:0043161; GO:0046872; GO:0048856; GO:0051865; GO:0060707; GO:0060708; GO:0061630; GO:0070534; GO:0072659; GO:1903077 21608 XM_044318511.1 93 67 240 454 293 Q9ULT8 1.98e-164 E3 ubiquitin-protein ligase HECTD1 (EC 2.3.2.26) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1) Homo sapiens (Human) anatomical structure development [GO:0048856]; aorta development [GO:0035904]; heart valve development [GO:0003170]; natural killer cell differentiation [GO:0001779]; negative regulation of protein localization to plasma membrane [GO:1903077]; neural tube closure [GO:0001843]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein localization to plasma membrane [GO:0072659]; protein polyubiquitination [GO:0000209]; spongiotrophoblast differentiation [GO:0060708]; trophoblast giant cell differentiation [GO:0060707]; ventricular septum development [GO:0003281] GO:0000209; GO:0001779; GO:0001843; GO:0003170; GO:0003281; GO:0016607; GO:0032436; GO:0035904; GO:0043161; GO:0046872; GO:0048856; GO:0051865; GO:0060707; GO:0060708; GO:0061630; GO:0070534; GO:0072659; GO:1903077 21609 XM_044318511.1 93 67 240 454 293 Q9ULT8 5.75e-103 E3 ubiquitin-protein ligase HECTD1 (EC 2.3.2.26) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1) Homo sapiens (Human) anatomical structure development [GO:0048856]; aorta development [GO:0035904]; heart valve development [GO:0003170]; natural killer cell differentiation [GO:0001779]; negative regulation of protein localization to plasma membrane [GO:1903077]; neural tube closure [GO:0001843]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein localization to plasma membrane [GO:0072659]; protein polyubiquitination [GO:0000209]; spongiotrophoblast differentiation [GO:0060708]; trophoblast giant cell differentiation [GO:0060707]; ventricular septum development [GO:0003281] GO:0000209; GO:0001779; GO:0001843; GO:0003170; GO:0003281; GO:0016607; GO:0032436; GO:0035904; GO:0043161; GO:0046872; GO:0048856; GO:0051865; GO:0060707; GO:0060708; GO:0061630; GO:0070534; GO:0072659; GO:1903077 21610 XR_006393324.1 283 468 191 175 334 Q9H4G4 1.8e-39 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Homo sapiens (Human) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070062; GO:0070374 21611 XR_006393324.1 283 468 191 175 334 Q9H4G4 1.75e-29 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Homo sapiens (Human) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070062; GO:0070374 21612 XR_006393324.1 283 468 191 175 334 Q9H4G4 1.73e-28 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Homo sapiens (Human) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070062; GO:0070374 21613 XR_006393324.1 283 468 191 175 334 Q9H4G4 1.23e-23 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Homo sapiens (Human) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070062; GO:0070374 21614 XM_029351803.2 97 10 8 0 6 NA NA NA NA NA NA 21615 XM_044309035.1 1031 956 448 1258 605 Q4R642 5.28e-161 Dynein regulatory complex subunit 5 (T-complex-associated testis-expressed protein 1) (Tcte-1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) flagellated sperm motility [GO:0030317] GO:0005737; GO:0005856; GO:0030317; GO:0036126 21616 XM_044311917.1 8 0 5 13 0 Q09811 4.34e-40 ATP-dependent DNA helicase hus2/rqh1 (EC 3.6.4.12) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) cellular response to DNA damage stimulus [GO:0006974]; DNA double-strand break processing [GO:0000729]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724]; maintenance of rDNA [GO:0043007]; mitotic intra-S DNA damage checkpoint signaling [GO:0031573]; mitotic recombination-dependent replication fork processing [GO:1990426]; postreplication repair [GO:0006301]; recombinational repair [GO:0000725]; regulation of mitotic recombination-dependent replication fork processing [GO:1903221]; replication fork processing [GO:0031297]; resolution of mitotic recombination intermediates [GO:0071140]; UV-damage excision repair [GO:0070914] GO:0000228; GO:0000724; GO:0000725; GO:0000729; GO:0003677; GO:0005524; GO:0005634; GO:0005694; GO:0005730; GO:0005737; GO:0006268; GO:0006281; GO:0006301; GO:0006310; GO:0006974; GO:0009378; GO:0016887; GO:0031297; GO:0031422; GO:0031573; GO:0032508; GO:0035861; GO:0043007; GO:0043138; GO:0043596; GO:0070914; GO:0071140; GO:1903221; GO:1990426 21617 XR_003823558.2 0 0 0 0 11 NA NA NA NA NA NA 21618 XM_029347067.2 972 990 853 1007 1189 P20933 3.55e-112 N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase (EC 3.5.1.26) (Aspartylglucosaminidase) (Glycosylasparaginase) (N4-(N-acetyl-beta-glucosaminyl)-L-asparagine amidase) [Cleaved into: Glycosylasparaginase alpha chain; Glycosylasparaginase beta chain] Homo sapiens (Human) protein deglycosylation [GO:0006517]; proteolysis [GO:0006508] GO:0003948; GO:0005576; GO:0005615; GO:0005737; GO:0005764; GO:0005783; GO:0006508; GO:0006517; GO:0008233; GO:0035578 21619 XM_029338840.2 0 0 17 0 21 O88871 1.73e-139 Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51) Rattus norvegicus (Rat) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; gamma-aminobutyric acid signaling pathway [GO:0007214]; neuron-glial cell signaling [GO:0150099]; synaptic transmission, GABAergic [GO:0051932] GO:0004888; GO:0004965; GO:0005737; GO:0005886; GO:0007193; GO:0007214; GO:0016020; GO:0030425; GO:0038039; GO:0042734; GO:0043005; GO:0043204; GO:0045211; GO:0046982; GO:0051932; GO:0098978; GO:0098982; GO:0150099; GO:1902710; GO:1902712 21620 XM_029340389.2 74 0 0 48 0 E9QAT4 1.14e-45 Protein transport protein Sec16A (SEC16 homolog A) (p250) Mus musculus (Mouse) autophagy [GO:0006914]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; Golgi to plasma membrane transport [GO:0006893]; protein exit from endoplasmic reticulum [GO:0032527]; protein localization to endoplasmic reticulum exit site [GO:0070973]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; response to endoplasmic reticulum stress [GO:0034976] GO:0000139; GO:0005789; GO:0005829; GO:0006888; GO:0006893; GO:0006914; GO:0007029; GO:0007030; GO:0012507; GO:0031090; GO:0032527; GO:0034976; GO:0048208; GO:0048471; GO:0050821; GO:0070971; GO:0070973; GO:0072659 21621 XR_006397596.1 19 13 6 9 1 NA NA NA NA NA NA 21622 XM_044310685.1 400 290 350 432 259 Q6GR35 2.09e-57 Protein Abitram (Actin-binding transcription modulator) (Protein Simiate) Xenopus laevis (African clawed frog) dendrite morphogenesis [GO:0048813]; regulation of actin filament polymerization [GO:0030833]; regulation of filopodium assembly [GO:0051489] GO:0016607; GO:0030027; GO:0030425; GO:0030426; GO:0030833; GO:0032433; GO:0048813; GO:0051489 21623 XM_029324619.2 17 4 30 15 177 NA NA NA NA NA NA 21624 XM_044316885.1 17 3 51 12 33 NA NA NA NA NA NA 21625 XM_044321957.1 382 441 2644 0 0 NA NA NA NA NA NA 21626 XM_044317380.1 301 131 1317 790 2314 Q96AY4 1.43e-47 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21627 XM_044317380.1 301 131 1317 790 2314 Q96AY4 8.49e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21628 XM_044317380.1 301 131 1317 790 2314 Q96AY4 1.84e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21629 XM_044317380.1 301 131 1317 790 2314 Q96AY4 1.14e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21630 XM_044317380.1 301 131 1317 790 2314 Q96AY4 1.97e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21631 XM_044317380.1 301 131 1317 790 2314 Q96AY4 7.86e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21632 XM_044317380.1 301 131 1317 790 2314 Q96AY4 1.17e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21633 XM_044317380.1 301 131 1317 790 2314 Q96AY4 1.2e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21634 XM_044317380.1 301 131 1317 790 2314 Q96AY4 3e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21635 XM_044317380.1 301 131 1317 790 2314 Q96AY4 1.67e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21636 XM_044320502.1 578 0 0 428 483 D3ZGB1 6.75e-33 Nuclear factor of activated T-cells 5 (NF-AT5) (T-cell transcription factor NFAT5) Rattus norvegicus (Rat) calcineurin-NFAT signaling cascade [GO:0033173]; cellular response to cytokine stimulus [GO:0071345]; cellular response to DNA damage stimulus [GO:0006974]; positive regulation of gene expression [GO:0010628]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R-loop processing [GO:0062176]; regulation of calcineurin-NFAT signaling cascade [GO:0070884]; regulation of transcription by RNA polymerase II [GO:0006357]; response to osmotic stress [GO:0006970] GO:0000978; GO:0000981; GO:0001228; GO:0003677; GO:0003682; GO:0005634; GO:0005654; GO:0005667; GO:0005694; GO:0005737; GO:0005829; GO:0006357; GO:0006970; GO:0006974; GO:0010628; GO:0033173; GO:0045944; GO:0062176; GO:0070884; GO:0071345; GO:1901224; GO:1904996; GO:1990837 21637 XM_044320026.1 123 4 50 39 51 NA NA NA NA NA NA 21638 XM_044327960.1 40 2 12 2 7 NA NA NA NA NA NA 21639 XM_029344402.2 64 98 80 31 52 NA NA NA NA NA NA 21640 XM_044315703.1 12 19 8 12 54 NA NA NA NA NA NA 21641 XM_029342453.2 217 113 107 310 137 NA NA NA NA NA NA 21642 XM_029348346.2 988 519 423 672 401 P31729 1.97e-63 OV-16 antigen Onchocerca volvulus NA NA 21643 XM_044310068.1 110 25 146 13 683 NA NA NA NA NA NA 21644 XM_029346009.2 1089 811 540 1065 505 Q32LN4 6.33e-102 Cilia- and flagella-associated protein 45 Bos taurus (Bovine) NA GO:0005879; GO:0031514 21645 XM_029350493.2 6 0 0 0 10 Q5C9Z4 5.89e-148 Nucleolar MIF4G domain-containing protein 1 (SGD1 homolog) Homo sapiens (Human) hair follicle maturation [GO:0048820]; ribosomal small subunit biogenesis [GO:0042274] GO:0003723; GO:0005730; GO:0042274; GO:0048820 21646 XM_044319895.1 34 46 39 0 29 Q9N294 1.77e-32 Beta-1,3-galactosyltransferase 5 (Beta-1,3-GalTase 5) (Beta3Gal-T5) (Beta3GalT5) (b3Gal-T5) (EC 2.4.1.-) (Beta-3-Gx-T5) (UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 5) (UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 5) Pan paniscus (Pygmy chimpanzee) (Bonobo) lipid metabolic process [GO:0006629]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0006629; GO:0016758 21647 XM_029339398.2 716 757 864 1131 1537 Q05B92 8.7e-52 Transcription factor E3 Bos taurus (Bovine) adaptive immune response [GO:0002250]; humoral immune response [GO:0006959]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell adhesion [GO:0045785]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of osteoclast differentiation [GO:0045670]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000976; GO:0000978; GO:0000981; GO:0001228; GO:0002250; GO:0003700; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006357; GO:0006959; GO:0045670; GO:0045785; GO:0045893; GO:0045944; GO:0046983; GO:0090336 21648 XR_006394746.1 4077 3480 1869 1520 2423 Q922Q5 6.72e-130 Adenosine 3'-phospho 5'-phosphosulfate transporter 2 (PAPS transporter 2) (Solute carrier family 35 member B3) Mus musculus (Mouse) NA GO:0000139; GO:0005739; GO:0005789; GO:0022857; GO:0046964 21649 XM_044307328.1 674 619 392 639 498 Q7T293 1.03e-32 Splicing regulator SDE2 (Replication stress response regulator SDE2) Danio rerio (Zebrafish) (Brachydanio rerio) cell cycle [GO:0007049]; cell division [GO:0051301]; DNA replication [GO:0006260]; endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000479]; mRNA cis splicing, via spliceosome [GO:0045292] GO:0000479; GO:0003677; GO:0005634; GO:0005737; GO:0006260; GO:0007049; GO:0030515; GO:0045292; GO:0051301 21650 XM_029349814.2 5262 7720 2466 6534 5752 P05631 2.37e-111 ATP synthase subunit gamma, mitochondrial (ATP synthase F1 subunit gamma) (F-ATPase gamma subunit) Bos taurus (Bovine) proton motive force-driven ATP synthesis [GO:0015986]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776] GO:0000275; GO:0005753; GO:0015986; GO:0042776; GO:0046933 21651 XM_044312680.1 0 0 9 0 0 NA NA NA NA NA NA 21652 XR_006396898.1 28 0 40 20 25 NA NA NA NA NA NA 21653 XR_006395234.1 432 691 232 795 1572 NA NA NA NA NA NA 21654 XM_029336244.2 186 143 105 745 658 NA NA NA NA NA NA 21655 XM_029324411.2 521 225 212 542 454 C9J069 4.56e-27 Apical junction component 1 homolog Homo sapiens (Human) cell-cell junction organization [GO:0045216] GO:0005886; GO:0005912; GO:0005929; GO:0016324; GO:0043296; GO:0045216 21656 XM_029333591.2 475 376 206 307 363 Q8RWD9 2.1e-26 Acyl-CoA-binding domain-containing protein 5 (Acyl-CoA binding protein 5) Arabidopsis thaliana (Mouse-ear cress) lipid transport [GO:0006869]; response to hypoxia [GO:0001666]; response to light stimulus [GO:0009416] GO:0000062; GO:0001666; GO:0005829; GO:0006869; GO:0009416 21657 XM_029339834.2 45 0 26 9 18 NA NA NA NA NA NA 21658 XM_044313133.1 367 281 276 632 191 NA NA NA NA NA NA 21659 XR_006394675.1 202 70 107 163 236 NA NA NA NA NA NA 21660 XM_029331871.2 2582 1220 1250 2660 3106 Q9NQ94 5.75e-167 APOBEC1 complementation factor (APOBEC1-stimulating protein) Homo sapiens (Human) cytidine to uridine editing [GO:0016554]; embryo implantation [GO:0007566]; mRNA localization resulting in post-transcriptional regulation of gene expression [GO:0010609]; mRNA modification [GO:0016556]; mRNA processing [GO:0006397]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; positive regulation of DNA demethylation [GO:1901537]; protein stabilization [GO:0050821] GO:0003723; GO:0003727; GO:0003729; GO:0005634; GO:0005654; GO:0005737; GO:0005783; GO:0006397; GO:0007566; GO:0010609; GO:0016554; GO:0016556; GO:0030895; GO:0045293; GO:0050821; GO:1901537; GO:2000623 21661 XM_029350356.2 4466 3242 2537 4303 3626 NA NA NA NA NA NA 21662 XM_044307289.1 250 35 51 66 222 D2IYS2 8.2e-65 Tyrosine-protein kinase receptor torso (EC 2.7.10.1) Bombyx mori (Silk moth) NA GO:0004714; GO:0005524; GO:0005886; GO:0046872 21663 XM_044327459.1 25 5 0 0 2 F8J3H2 2.84e-24 NA NA NA NA 21664 XM_029358020.2 0 0 12 0 40 P29029 7.62e-47 Endochitinase (EC 3.2.1.14) (Soluble cell wall protein 2) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) cell wall organization [GO:0071555]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]; septum digestion after cytokinesis [GO:0000920] GO:0000272; GO:0000324; GO:0000920; GO:0004568; GO:0005576; GO:0005635; GO:0005783; GO:0005935; GO:0006032; GO:0008061; GO:0008843; GO:0009277; GO:0071555 21665 XM_044326060.1 237 40 298 2 0 NA NA NA NA NA NA 21666 XM_029337967.2 170 146 81 129 203 Q9CSH3 0 Exosome complex exonuclease RRP44 (EC 3.1.13.-) (EC 3.1.26.-) (Protein DIS3 homolog) (Ribosomal RNA-processing protein 44) Mus musculus (Mouse) CUT catabolic process [GO:0071034]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364] GO:0000175; GO:0000176; GO:0000177; GO:0000178; GO:0003723; GO:0004519; GO:0005085; GO:0005634; GO:0005654; GO:0005730; GO:0005829; GO:0006364; GO:0006396; GO:0006401; GO:0016075; GO:0071034 21667 XM_044322612.1 30 0 10 2 19 Q99315 1.19e-93 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 21668 XM_044313874.1 23 18 19 25 36 Q96AY4 8.13e-110 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21669 XM_044313874.1 23 18 19 25 36 Q96AY4 1.19e-104 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21670 XM_044313874.1 23 18 19 25 36 Q96AY4 2.52e-104 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21671 XM_044313874.1 23 18 19 25 36 Q96AY4 8.8e-104 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21672 XM_044313874.1 23 18 19 25 36 Q96AY4 2.02e-102 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21673 XM_044313874.1 23 18 19 25 36 Q96AY4 6.74e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21674 XM_044313874.1 23 18 19 25 36 Q96AY4 2.61e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21675 XM_044313874.1 23 18 19 25 36 Q96AY4 4.58e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21676 XM_044327714.1 4032 3332 1867 3356 3128 Q7ZW25 6.85e-82 Charged multivesicular body protein 2a (Chromatin-modifying protein 2a) (CHMP2a) Danio rerio (Zebrafish) (Brachydanio rerio) endosome transport via multivesicular body sorting pathway [GO:0032509]; exit from mitosis [GO:0010458]; late endosome to vacuole transport [GO:0045324]; nuclear membrane reassembly [GO:0031468]; protein transport [GO:0015031] GO:0000815; GO:0005635; GO:0005771; GO:0010458; GO:0015031; GO:0031468; GO:0031902; GO:0032509; GO:0045324 21677 XM_029340773.2 196 77 154 138 219 NA NA NA NA NA NA 21678 XM_029351444.2 0 25 0 20 0 B8VIU6 7.36e-50 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 21679 XM_044327252.1 49 20 32 23 14 NA NA NA NA NA NA 21680 XM_044327591.1 457 436 256 460 589 O13046 0 WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA-binding protein 1) (And-1) Xenopus laevis (African clawed frog) NA GO:0003677; GO:0005654; GO:0005737 21681 XM_029339022.2 4416 5217 3324 5330 2061 P63018 0 Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) Rattus norvegicus (Rat) aging [GO:0007568]; ATP metabolic process [GO:0046034]; axo-dendritic transport [GO:0008088]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; cerebellum development [GO:0021549]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein folding [GO:0061077]; clathrin coat disassembly [GO:0072318]; estrous cycle [GO:0044849]; forebrain development [GO:0030900]; G1/S transition of mitotic cell cycle [GO:0000082]; kidney development [GO:0001822]; late endosomal microautophagy [GO:0061738]; maintenance of postsynaptic specialization structure [GO:0098880]; modulation by host of viral process [GO:0044788]; mRNA processing [GO:0006397]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of supramolecular fiber organization [GO:1902904]; positive regulation by host of viral genome replication [GO:0044829]; positive regulation of catalytic activity [GO:0043085]; positive regulation of gene expression [GO:0010628]; positive regulation of lysosomal membrane permeability [GO:0097214]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein refolding [GO:1904592]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein autophosphorylation [GO:0046777]; protein folding [GO:0006457]; protein import into nucleus [GO:0006606]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; protein transmembrane import into intracellular organelle [GO:0044743]; protein-containing complex disassembly [GO:0032984]; regulation of cell cycle [GO:0051726]; regulation of postsynapse organization [GO:0099175]; regulation of protein complex stability [GO:0061635]; regulation of protein stability [GO:0031647]; response to activity [GO:0014823]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to nickel cation [GO:0010045]; response to odorant [GO:1990834]; response to progesterone [GO:0032570]; response to starvation [GO:0042594]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; sensory perception of smell [GO:0007608]; skeletal muscle tissue development [GO:0007519]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192] GO:0000082; GO:0000974; GO:0001664; GO:0001786; GO:0001822; GO:0001916; GO:0001917; GO:0003723; GO:0005102; GO:0005524; GO:0005634; GO:0005681; GO:0005730; GO:0005737; GO:0005764; GO:0005765; GO:0005770; GO:0005776; GO:0005829; GO:0005874; GO:0005882; GO:0005886; GO:0006397; GO:0006457; GO:0006606; GO:0007519; GO:0007568; GO:0007608; GO:0008021; GO:0008088; GO:0008380; GO:0009408; GO:0009410; GO:0009986; GO:0010045; GO:0010628; GO:0010667; GO:0014069; GO:0014823; GO:0016191; GO:0016192; GO:0016887; GO:0019899; GO:0021549; GO:0030424; GO:0030425; GO:0030674; GO:0030900; GO:0031072; GO:0031625; GO:0031647; GO:0031686; GO:0032279; GO:0032355; GO:0032570; GO:0032984; GO:0032991; GO:0034605; GO:0034620; GO:0042026; GO:0042277; GO:0042470; GO:0042594; GO:0043005; GO:0043025; GO:0043085; GO:0043195; GO:0043197; GO:0043198; GO:0043202; GO:0043204; GO:0043531; GO:0044183; GO:0044309; GO:0044743; GO:0044788; GO:0044829; GO:0044849; GO:0045121; GO:0045471; GO:0045862; GO:0045892; GO:0046034; GO:0046777; GO:0048026; GO:0048471; GO:0050766; GO:0051082; GO:0051085; GO:0051087; GO:0051726; GO:0051787; GO:0055131; GO:0061077; GO:0061635; GO:0061684; GO:0061738; GO:0061740; GO:0070062; GO:0071276; GO:0072318; GO:0097214; GO:0098684; GO:0098690; GO:0098793; GO:0098794; GO:0098880; GO:0098978; GO:0099175; GO:0099523; GO:0099524; GO:0099634; GO:0101031; GO:0140545; GO:0140662; GO:1902904; GO:1903206; GO:1904592; GO:1904593; GO:1904764; GO:1990124; GO:1990832; GO:1990833; GO:1990834; GO:1990836; GO:1990904 21682 XM_044329210.1 0 155 0 419 175 NA NA NA NA NA NA 21683 XM_029350532.2 4352 3138 968 3303 5598 NA NA NA NA NA NA 21684 XM_029347605.2 163 262 0 379 73 Q8IS64 3.95e-156 Endothelin-converting enzyme homolog (ECE) (EC 3.4.24.-) Locusta migratoria (Migratory locust) proteolysis [GO:0006508] GO:0004175; GO:0004222; GO:0005886; GO:0006508; GO:0008270 21685 XM_029345311.2 99 61 52 156 110 NA NA NA NA NA NA 21686 XR_006397113.1 191 212 80 1517 463 NA NA NA NA NA NA 21687 XM_044322534.1 26 0 2 0 0 A4Q9F3 2.13e-25 Protein polyglycylase TTLL10 (EC 6.3.2.-) (Tubulin--tyrosine ligase-like protein 10) Mus musculus (Mouse) protein polyglycylation [GO:0018094] GO:0005524; GO:0005874; GO:0005929; GO:0005930; GO:0015630; GO:0018094; GO:0046872; GO:0070735; GO:0070737 21688 XM_044325859.1 0 0 0 0 13 NA NA NA NA NA NA 21689 XM_029351534.2 382 212 341 347 387 Q9H9Y6 0 DNA-directed RNA polymerase I subunit RPA2 (RNA polymerase I subunit 2) (EC 2.7.7.6) (DNA-directed RNA polymerase I 135 kDa polypeptide) (RPA135) Homo sapiens (Human) embryo implantation [GO:0007566]; neural crest formation [GO:0014029]; nucleologenesis [GO:0017126]; rRNA transcription [GO:0009303] GO:0001650; GO:0003677; GO:0003899; GO:0005654; GO:0005694; GO:0005736; GO:0005829; GO:0007566; GO:0009303; GO:0014029; GO:0017126; GO:0032549; GO:0046872 21690 XM_044317845.1 20 0 0 14 23 NA NA NA NA NA NA 21691 XR_006393050.1 301 0 0 25 235 Q3MSQ8 8.4e-162 Probable ATP-dependent RNA helicase DDX4 (EC 3.6.4.13) (DEAD box protein 4) (Vasa homolog) Pelophylax lessonae (Pool frog) (Rana lessonae) DNA methylation involved in gamete generation [GO:0043046]; male meiosis I [GO:0007141]; male meiotic nuclear division [GO:0007140]; negative regulation of transposition [GO:0010529]; oogenesis [GO:0048477]; piRNA processing [GO:0034587]; spermatogenesis [GO:0007283] GO:0003676; GO:0003724; GO:0005524; GO:0007140; GO:0007141; GO:0007283; GO:0010529; GO:0016887; GO:0034587; GO:0043046; GO:0048477; GO:0071546; GO:0071547 21692 XM_029357108.2 39 75 44 87 70 NA NA NA NA NA NA 21693 XR_003826238.2 95 852 262 92 250 NA NA NA NA NA NA 21694 XM_029330317.2 2729 2622 1595 2374 2561 P54612 0 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A subunit A isoform PR65-alpha) (PP2A subunit A isoform R1-alpha) Sus scrofa (Pig) chromosome segregation [GO:0007059]; protein dephosphorylation [GO:0006470] GO:0000159; GO:0000775; GO:0005634; GO:0005737; GO:0006470; GO:0007059; GO:0016328; GO:0019888; GO:0030425 21695 XR_006393806.1 0 2 1 13 0 NA NA NA NA NA NA 21696 XM_029345443.2 147447 135614 79492 129182 40274 A1Z6E0 3.12e-114 Protein gustavus Drosophila melanogaster (Fruit fly) cuticle pattern formation [GO:0035017]; dorsal appendage formation [GO:0046843]; germ cell development [GO:0007281]; intracellular signal transduction [GO:0035556]; oocyte anterior/posterior axis specification [GO:0007314]; pole cell migration [GO:0007280]; pole plasm assembly [GO:0007315]; positive regulation of protein catabolic process [GO:0045732]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein localization [GO:0008104]; wing disc morphogenesis [GO:0007472] GO:0005634; GO:0005737; GO:0005938; GO:0007280; GO:0007281; GO:0007314; GO:0007315; GO:0007472; GO:0008104; GO:0019005; GO:0031466; GO:0035017; GO:0035556; GO:0043161; GO:0045495; GO:0045732; GO:0046843; GO:0048471; GO:0070449 21697 XM_044316863.1 0 14 5 5 0 F7J220 1.41e-28 Scavenger receptor cysteine-rich domain superfamily protein (ApSRCR1) Patiria pectinifera (Starfish) (Asterina pectinifera) innate immune response [GO:0045087]; phagocytosis [GO:0006909] GO:0005044; GO:0006909; GO:0030659; GO:0045087 21698 XM_044316863.1 0 14 5 5 0 F7J220 3.1e-24 Scavenger receptor cysteine-rich domain superfamily protein (ApSRCR1) Patiria pectinifera (Starfish) (Asterina pectinifera) innate immune response [GO:0045087]; phagocytosis [GO:0006909] GO:0005044; GO:0006909; GO:0030659; GO:0045087 21699 XM_044316863.1 0 14 5 5 0 F7J220 1.2e-23 Scavenger receptor cysteine-rich domain superfamily protein (ApSRCR1) Patiria pectinifera (Starfish) (Asterina pectinifera) innate immune response [GO:0045087]; phagocytosis [GO:0006909] GO:0005044; GO:0006909; GO:0030659; GO:0045087 21700 XM_044316863.1 0 14 5 5 0 F7J220 8.9e-22 Scavenger receptor cysteine-rich domain superfamily protein (ApSRCR1) Patiria pectinifera (Starfish) (Asterina pectinifera) innate immune response [GO:0045087]; phagocytosis [GO:0006909] GO:0005044; GO:0006909; GO:0030659; GO:0045087 21701 XM_044316863.1 0 14 5 5 0 F7J220 7.77e-21 Scavenger receptor cysteine-rich domain superfamily protein (ApSRCR1) Patiria pectinifera (Starfish) (Asterina pectinifera) innate immune response [GO:0045087]; phagocytosis [GO:0006909] GO:0005044; GO:0006909; GO:0030659; GO:0045087 21702 XM_044311471.1 80 61 105 27 394 NA NA NA NA NA NA 21703 XR_006391520.1 0 0 59 0 55 NA NA NA NA NA NA 21704 XR_006395100.1 11 42 19 40 24 NA NA NA NA NA NA 21705 XM_029337537.2 0 0 0 22 66 Q9YHV3 1.83e-33 Noggin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cartilage development [GO:0051216]; cloaca development [GO:0035844]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic viscerocranium morphogenesis [GO:0048703]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell differentiation [GO:0045596]; osteoblast differentiation [GO:0001649]; pronephros development [GO:0048793] GO:0001649; GO:0005615; GO:0007368; GO:0009953; GO:0030514; GO:0035844; GO:0045596; GO:0048703; GO:0048793; GO:0051216 21706 XM_044323810.1 0 4 9 37 0 NA NA NA NA NA NA 21707 XM_044310271.1 21 0 19 6 105 NA NA NA NA NA NA 21708 XM_044321604.1 273 198 171 733 85 NA NA NA NA NA NA 21709 XM_044321265.1 170 116 131 370 219 Q7RTR2 8.65e-40 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 21710 XM_044321265.1 170 116 131 370 219 Q7RTR2 1.58e-39 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 21711 XM_044321265.1 170 116 131 370 219 Q7RTR2 8.85e-39 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 21712 XM_044321265.1 170 116 131 370 219 Q7RTR2 8.44e-30 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 21713 XM_044323834.1 0 0 0 1 12 NA NA NA NA NA NA 21714 XM_044307142.1 260 92 151 255 226 Q99698 0 Lysosomal-trafficking regulator (Beige homolog) Homo sapiens (Human) defense response to bacterium [GO:0042742]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; leukocyte chemotaxis [GO:0030595]; mast cell secretory granule organization [GO:0033364]; melanosome organization [GO:0032438]; natural killer cell mediated cytotoxicity [GO:0042267]; phagocytosis [GO:0006909]; pigmentation [GO:0043473]; protein localization [GO:0008104]; protein transport [GO:0015031] GO:0005829; GO:0006909; GO:0008104; GO:0015031; GO:0015630; GO:0016020; GO:0019901; GO:0030595; GO:0032438; GO:0032510; GO:0033364; GO:0042267; GO:0042742; GO:0042832; GO:0043473; GO:0051607 21715 XM_044307142.1 260 92 151 255 226 Q99698 4.34e-48 Lysosomal-trafficking regulator (Beige homolog) Homo sapiens (Human) defense response to bacterium [GO:0042742]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; leukocyte chemotaxis [GO:0030595]; mast cell secretory granule organization [GO:0033364]; melanosome organization [GO:0032438]; natural killer cell mediated cytotoxicity [GO:0042267]; phagocytosis [GO:0006909]; pigmentation [GO:0043473]; protein localization [GO:0008104]; protein transport [GO:0015031] GO:0005829; GO:0006909; GO:0008104; GO:0015031; GO:0015630; GO:0016020; GO:0019901; GO:0030595; GO:0032438; GO:0032510; GO:0033364; GO:0042267; GO:0042742; GO:0042832; GO:0043473; GO:0051607 21716 XM_044307231.1 2051 1636 13 28 8 Q7M456 5.85e-33 Ribonuclease Oy (RNase Oy) (EC 3.1.27.-) Crassostrea gigas (Pacific oyster) (Crassostrea angulata) NA GO:0003723; GO:0005576; GO:0033897 21717 XM_029352967.2 14 34 1 66 2 NA NA NA NA NA NA 21718 XR_006392369.1 100 89 4 73 0 NA NA NA NA NA NA 21719 XM_029353313.2 2 9 0 35 0 P51954 1.43e-55 Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase 1) (NimA-related protein kinase 1) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; cilium assembly [GO:0060271]; kidney development [GO:0001822]; multicellular organism growth [GO:0035264]; protein phosphorylation [GO:0006468]; regulation of DNA damage checkpoint [GO:2000001]; response to ionizing radiation [GO:0010212]; spermatogenesis [GO:0007283] GO:0000242; GO:0001822; GO:0004672; GO:0004674; GO:0004713; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0005829; GO:0006468; GO:0006974; GO:0007049; GO:0007283; GO:0010212; GO:0016301; GO:0034451; GO:0035264; GO:0046872; GO:0051301; GO:0060271; GO:0071889; GO:0106310; GO:2000001 21720 XM_029358167.2 158 0 0 0 0 O00628 3.89e-128 Peroxisomal targeting signal 2 receptor (PTS2 receptor) (Peroxin-7) Homo sapiens (Human) endochondral ossification [GO:0001958]; ether lipid biosynthetic process [GO:0008611]; fatty acid beta-oxidation [GO:0006635]; neuron migration [GO:0001764]; peroxisome organization [GO:0007031]; protein import into peroxisome matrix [GO:0016558] GO:0001764; GO:0001958; GO:0005053; GO:0005777; GO:0005778; GO:0005782; GO:0005829; GO:0006635; GO:0007031; GO:0008611; GO:0016558; GO:0019899; GO:0042803 21721 XM_044308672.1 45 42 189 151 265 NA NA NA NA NA NA 21722 XM_044318992.1 62 52 143 33 302 NA NA NA NA NA NA 21723 XM_044317618.1 323 66 89 33 0 NA NA NA NA NA NA 21724 XM_044317774.1 94 58 53 103 110 Q8BHT6 1.81e-135 Beta-1,3-glucosyltransferase (Beta3Glc-T) (EC 2.4.1.-) (Beta 3-glucosyltransferase) (Beta-3-glycosyltransferase-like) Mus musculus (Mouse) fucose metabolic process [GO:0006004]; protein glycosylation [GO:0006486] GO:0005789; GO:0006004; GO:0006486; GO:0008375 21725 XM_029324153.2 2716 3473 1509 1804 1584 NA NA NA NA NA NA 21726 XM_029344978.2 0 0 242 1367 191 Q8NF64 6.74e-140 Zinc finger MIZ domain-containing protein 2 (PIAS-like protein Zimp7) Homo sapiens (Human) positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0005634; GO:0005654; GO:0005739; GO:0006357; GO:0008270; GO:0030374; GO:0043596; GO:0045944 21727 XM_044325216.1 66 0 0 0 0 NA NA NA NA NA NA 21728 XM_044323977.1 7 0 21 1 93 NA NA NA NA NA NA 21729 XM_044328032.1 66 50 90 76 42 O34383 9.98e-22 Uncharacterized sodium-dependent transporter YocR Bacillus subtilis (strain 168) NA GO:0005886; GO:0015293 21730 XM_029340977.2 2344 1538 985 2032 1515 Q7SYJ9 3.46e-63 Sperm-associated antigen 7 homolog Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0003676 21731 XM_029343119.2 103 74 64 179 88 O88943 6.52e-73 Potassium voltage-gated channel subfamily KQT member 2 (KQT-like 2) (Potassium channel subunit alpha KvLQT2) (Voltage-gated potassium channel subunit Kv7.2) Rattus norvegicus (Rat) ion transmembrane transport [GO:0034220]; membrane hyperpolarization [GO:0060081]; potassium ion transmembrane transport [GO:0071805]; regulation of ion transmembrane transport [GO:0034765]; transmission of nerve impulse [GO:0019226] GO:0005244; GO:0005249; GO:0005251; GO:0005516; GO:0005886; GO:0008076; GO:0009986; GO:0016020; GO:0019226; GO:0030506; GO:0032991; GO:0033268; GO:0034220; GO:0034765; GO:0043194; GO:0047485; GO:0060081; GO:0071805 21732 XM_029355474.2 362 303 243 0 354 P10894 0 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (EC 3.1.4.11) (PLC-154) (Phosphoinositide phospholipase C-beta-1) (Phospholipase C-beta-1) (PLC-beta-1) Bos taurus (Bovine) interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-15-mediated signaling pathway [GO:0035723]; lipid catabolic process [GO:0016042]; memory [GO:0007613]; phosphatidylinositol metabolic process [GO:0046488]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of JNK cascade [GO:0046330] GO:0004435; GO:0005096; GO:0005509; GO:0005516; GO:0005546; GO:0005737; GO:0005829; GO:0007613; GO:0016042; GO:0016607; GO:0019899; GO:0031965; GO:0035722; GO:0035723; GO:0046330; GO:0046488; GO:0048015; GO:0070498 21733 XM_044328215.1 40 33 24 28 54 E1BYJ2 0 DNA mismatch repair protein Msh6 Gallus gallus (Chicken) mismatch repair [GO:0006298]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; negative regulation of DNA endoreduplication [GO:0032876]; positive regulation of B cell proliferation [GO:0030890] GO:0003690; GO:0005524; GO:0005634; GO:0006298; GO:0007095; GO:0030890; GO:0030983; GO:0032301; GO:0032876; GO:0140664 21734 XR_006392342.1 89 55 12 30 16 Q99570 7.69e-145 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 21735 XM_044314547.1 5 6 1 0 11 NA NA NA NA NA NA 21736 XM_044326406.1 40 0 0 0 0 P30975 1.96e-25 Tachykinin-like peptides receptor 99D (Tachykinin-like receptor at 99D) (dTKR) Drosophila melanogaster (Fruit fly) detection of chemical stimulus involved in sensory perception of smell [GO:0050911]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; neuropeptide signaling pathway [GO:0007218]; olfactory behavior [GO:0042048]; positive regulation of sensory perception of pain [GO:1904058]; tachykinin receptor signaling pathway [GO:0007217] GO:0004995; GO:0005886; GO:0007186; GO:0007217; GO:0007218; GO:0008188; GO:0016020; GO:0042048; GO:0050805; GO:0050911; GO:1904058 21737 XM_044316494.1 0 0 10 0 0 NA NA NA NA NA NA 21738 XM_044323400.1 0 1 64 254 6 NA NA NA NA NA NA 21739 XM_029348102.2 0 93 61 85 139 P56705 2.9e-139 Protein Wnt-4 Homo sapiens (Human) adrenal gland development [GO:0030325]; apoptotic signaling pathway [GO:0097190]; branching involved in ureteric bud morphogenesis [GO:0001658]; canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; cellular response to starvation [GO:0009267]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic epithelial tube formation [GO:0001838]; epithelial to mesenchymal transition [GO:0001837]; female gonad development [GO:0008585]; female sex determination [GO:0030237]; fibroblast growth factor receptor signaling pathway [GO:0008543]; hormone metabolic process [GO:0042445]; immature T cell proliferation in thymus [GO:0033080]; kidney development [GO:0001822]; liver development [GO:0001889]; male gonad development [GO:0008584]; mammary gland epithelium development [GO:0061180]; meiotic nuclear division [GO:0140013]; mesenchymal to epithelial transition [GO:0060231]; metanephric mesenchymal cell differentiation [GO:0072162]; metanephric nephron morphogenesis [GO:0072273]; metanephric tubule formation [GO:0072174]; negative regulation of androgen biosynthetic process [GO:2000180]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell migration [GO:0030336]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; negative regulation of gene expression [GO:0010629]; negative regulation of male gonad development [GO:2000019]; negative regulation of steroid biosynthetic process [GO:0010894]; negative regulation of testicular blood vessel morphogenesis [GO:0061369]; negative regulation of testosterone biosynthetic process [GO:2000225]; negative regulation of wound healing [GO:0061045]; neuron differentiation [GO:0030182]; non-canonical Wnt signaling pathway via MAPK cascade [GO:0038030]; oocyte development [GO:0048599]; paramesonephric duct development [GO:0061205]; pericyte cell differentiation [GO:1904238]; positive regulation of aldosterone biosynthetic process [GO:0032349]; positive regulation of bone mineralization [GO:0030501]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of cortisol biosynthetic process [GO:2000066]; positive regulation of dermatome development [GO:0061184]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of GTPase activity [GO:0043547]; positive regulation of meiotic nuclear division [GO:0045836]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of stress fiber assembly [GO:0051496]; regulation of cell-cell adhesion [GO:0022407]; renal vesicle formation [GO:0072033]; renal vesicle induction [GO:0072034]; Sertoli cell differentiation [GO:0060008]; smooth muscle cell differentiation [GO:0051145]; somatotropin secreting cell differentiation [GO:0060126]; tertiary branching involved in mammary gland duct morphogenesis [GO:0060748]; thyroid-stimulating hormone-secreting cell differentiation [GO:0060129] GO:0001658; GO:0001822; GO:0001837; GO:0001838; GO:0001889; GO:0003714; GO:0005109; GO:0005125; GO:0005576; GO:0005615; GO:0005737; GO:0005788; GO:0005796; GO:0005886; GO:0008543; GO:0008584; GO:0008585; GO:0009267; GO:0009986; GO:0010629; GO:0010894; GO:0022407; GO:0030182; GO:0030237; GO:0030325; GO:0030336; GO:0030501; GO:0030666; GO:0031012; GO:0032349; GO:0032967; GO:0033080; GO:0038030; GO:0040037; GO:0042445; GO:0043547; GO:0045165; GO:0045596; GO:0045669; GO:0045836; GO:0045892; GO:0045893; GO:0048018; GO:0048599; GO:0051145; GO:0051496; GO:0051894; GO:0060008; GO:0060070; GO:0060126; GO:0060129; GO:0060231; GO:0060748; GO:0061045; GO:0061180; GO:0061184; GO:0061205; GO:0061369; GO:0070062; GO:0071560; GO:0072033; GO:0072034; GO:0072162; GO:0072174; GO:0072273; GO:0097190; GO:0140013; GO:1904238; GO:2000019; GO:2000066; GO:2000180; GO:2000225; GO:2001234 21740 XM_044317631.1 80 0 149 29 573 Q5RHH4 0 Intraflagellar transport protein 172 homolog Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; intraciliary transport [GO:0042073]; photoreceptor cell maintenance [GO:0045494]; pronephros development [GO:0048793]; regulation of TOR signaling [GO:0032006]; retina development in camera-type eye [GO:0060041] GO:0005929; GO:0005930; GO:0030992; GO:0032006; GO:0036064; GO:0042073; GO:0045494; GO:0048793; GO:0060041; GO:0060271 21741 XM_029346988.2 1 2 15 0 68 NA NA NA NA NA NA 21742 XM_044321924.1 59 23 19 60 83 Q54H55 1.19e-41 FAD-linked oxidoreductase DDB_G0289697 (EC 1.-.-.-) Dictyostelium discoideum (Social amoeba) NA GO:0016491; GO:0071949 21743 XM_044308773.1 0 19 1 3 17 NA NA NA NA NA NA 21744 XM_044327022.1 3068 3984 1989 3830 1972 NA NA NA NA NA NA 21745 XR_006391401.1 18 19 28 19 19 NA NA NA NA NA NA 21746 XM_029356665.2 1620 1648 1361 2386 2720 Q00174 0 Laminin subunit alpha (Laminin A chain) Drosophila melanogaster (Fruit fly) animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; basement membrane organization [GO:0071711]; cell adhesion mediated by integrin [GO:0033627]; dorsal trunk growth, open tracheal system [GO:0035001]; heart development [GO:0007507]; melanotic encapsulation of foreign target [GO:0035011]; mesoderm development [GO:0007498]; negative regulation of synaptic assembly at neuromuscular junction [GO:0045886]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888] GO:0005102; GO:0005576; GO:0005604; GO:0007411; GO:0007498; GO:0007507; GO:0008021; GO:0009887; GO:0009888; GO:0030155; GO:0030334; GO:0030424; GO:0033627; GO:0034446; GO:0035001; GO:0035011; GO:0036062; GO:0045886; GO:0045995; GO:0062023; GO:0071711 21747 XM_029356665.2 1620 1648 1361 2386 2720 Q00174 1.71e-24 Laminin subunit alpha (Laminin A chain) Drosophila melanogaster (Fruit fly) animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; basement membrane organization [GO:0071711]; cell adhesion mediated by integrin [GO:0033627]; dorsal trunk growth, open tracheal system [GO:0035001]; heart development [GO:0007507]; melanotic encapsulation of foreign target [GO:0035011]; mesoderm development [GO:0007498]; negative regulation of synaptic assembly at neuromuscular junction [GO:0045886]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888] GO:0005102; GO:0005576; GO:0005604; GO:0007411; GO:0007498; GO:0007507; GO:0008021; GO:0009887; GO:0009888; GO:0030155; GO:0030334; GO:0030424; GO:0033627; GO:0034446; GO:0035001; GO:0035011; GO:0036062; GO:0045886; GO:0045995; GO:0062023; GO:0071711 21748 XM_029348095.2 0 0 0 7 0 O89103 2.62e-21 Complement component C1q receptor (C1q/MBL/SPA receptor) (C1qR(p)) (C1qRp) (Cell surface antigen AA4) (Complement component 1 q subcomponent receptor 1) (Lymphocyte antigen 68) (Ly-68) (CD antigen CD93) Mus musculus (Mouse) cell-cell adhesion [GO:0098609] GO:0001849; GO:0005509; GO:0005886; GO:0009986; GO:0030246; GO:0031410; GO:0098609 21749 XM_029349124.2 3041 2710 1508 2630 3086 Q4R7K1 6.24e-113 mRNA cap guanine-N7 methyltransferase (EC 2.1.1.56) (RG7MT1) (mRNA (guanine-N(7))-methyltransferase) (mRNA cap methyltransferase) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) 7-methylguanosine mRNA capping [GO:0006370] GO:0003723; GO:0004482; GO:0005634; GO:0005845; GO:0006370 21750 XR_006392979.1 41 2 25 5 151 NA NA NA NA NA NA 21751 XM_044321724.1 584 948 752 772 480 NA NA NA NA NA NA 21752 XR_006395628.1 1011 592 428 664 513 O54865 0 Guanylate cyclase soluble subunit beta-1 (GCS-beta-1) (EC 4.6.1.2) (Guanylate cyclase soluble subunit beta-3) (GCS-beta-3) (Soluble guanylate cyclase small subunit) Mus musculus (Mouse) cellular response to nitric oxide [GO:0071732]; cGMP biosynthetic process [GO:0006182]; cGMP-mediated signaling [GO:0019934]; nitric oxide-cGMP-mediated signaling pathway [GO:0038060]; response to oxygen levels [GO:0070482]; trans-synaptic signaling by nitric oxide, modulating synaptic transmission [GO:0099555] GO:0004016; GO:0004383; GO:0005525; GO:0005737; GO:0006182; GO:0008074; GO:0019934; GO:0020037; GO:0032991; GO:0038060; GO:0043167; GO:0044877; GO:0046872; GO:0047805; GO:0048786; GO:0051879; GO:0070482; GO:0071732; GO:0098831; GO:0098978; GO:0099555 21753 XR_006395628.1 1011 592 428 664 513 O54865 2.95e-159 Guanylate cyclase soluble subunit beta-1 (GCS-beta-1) (EC 4.6.1.2) (Guanylate cyclase soluble subunit beta-3) (GCS-beta-3) (Soluble guanylate cyclase small subunit) Mus musculus (Mouse) cellular response to nitric oxide [GO:0071732]; cGMP biosynthetic process [GO:0006182]; cGMP-mediated signaling [GO:0019934]; nitric oxide-cGMP-mediated signaling pathway [GO:0038060]; response to oxygen levels [GO:0070482]; trans-synaptic signaling by nitric oxide, modulating synaptic transmission [GO:0099555] GO:0004016; GO:0004383; GO:0005525; GO:0005737; GO:0006182; GO:0008074; GO:0019934; GO:0020037; GO:0032991; GO:0038060; GO:0043167; GO:0044877; GO:0046872; GO:0047805; GO:0048786; GO:0051879; GO:0070482; GO:0071732; GO:0098831; GO:0098978; GO:0099555 21754 XM_044325751.1 228 0 10 1 5 NA NA NA NA NA NA 21755 XM_044315104.1 709 3346 1609 3107 524 NA NA NA NA NA NA 21756 XM_044322271.1 0 0 11 0 0 NA NA NA NA NA NA 21757 XM_029347746.2 863 1017 501 965 890 B2RY50 0 Outer dynein arm-docking complex subunit 2 (Armadillo repeat-containing protein 4) Mus musculus (Mouse) cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; outer dynein arm assembly [GO:0036158]; regulation of cilium beat frequency [GO:0003356]; ventricular system development [GO:0021591] GO:0003341; GO:0003356; GO:0005930; GO:0007368; GO:0007507; GO:0021591; GO:0036158; GO:0097546 21758 XM_029336159.2 129 0 0 0 0 Q6AZB8 4.39e-27 Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0004518; GO:0005634; GO:0005737; GO:0046872 21759 XM_044318293.1 1519 545 76 722 2742 NA NA NA NA NA NA 21760 XM_044307954.1 0 59 22 164 75 NA NA NA NA NA NA 21761 XM_044313250.1 1134 548 701 1253 721 Q04637 6.1e-177 Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G 1) (eIF-4G1) (p220) Homo sapiens (Human) behavioral fear response [GO:0001662]; cap-dependent translational initiation [GO:0002191]; cellular macromolecule biosynthetic process [GO:0034645]; cellular response to nutrient levels [GO:0031669]; energy homeostasis [GO:0097009]; lung development [GO:0030324]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of autophagy [GO:0010507]; negative regulation of neuron death [GO:1901215]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; neuron differentiation [GO:0030182]; positive regulation of cell death [GO:0010942]; positive regulation of cell growth [GO:0030307]; positive regulation of eukaryotic translation initiation factor 4F complex assembly [GO:1905537]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of mRNA cap binding [GO:1905612]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of translation in response to endoplasmic reticulum stress [GO:0036493]; regulation of cellular response to stress [GO:0080135]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of polysome binding [GO:1905696]; regulation of presynapse assembly [GO:1905606]; regulation of translational initiation [GO:0006446]; response to ethanol [GO:0045471]; translation [GO:0006412]; translational initiation [GO:0006413] GO:0001662; GO:0002191; GO:0003723; GO:0003729; GO:0003743; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0005844; GO:0006412; GO:0006413; GO:0006446; GO:0008135; GO:0008190; GO:0010494; GO:0010507; GO:0010801; GO:0010942; GO:0016020; GO:0016281; GO:0030182; GO:0030307; GO:0030324; GO:0031369; GO:0031669; GO:0033138; GO:0034645; GO:0035278; GO:0036493; GO:0042802; GO:0045471; GO:0045666; GO:0051247; GO:0060090; GO:0060964; GO:0080135; GO:0097009; GO:0098794; GO:1900087; GO:1901215; GO:1905537; GO:1905606; GO:1905612; GO:1905696 21762 XM_029348921.2 72 90 0 0 96 B8VIU6 1.11e-52 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 21763 XM_044321062.1 112 10 36 60 65 S8FIE4 1.53e-40 Laccase-1 (EC 1.10.3.2) (FpLCC1) Fomitopsis pinicola (strain FP-58527) (Brown rot fungus) NA GO:0005507; GO:0005576; GO:0016682 21764 XM_029338779.2 3092 2990 3247 4584 6042 P36895 1.06e-164 Bone morphogenetic protein receptor type-1A (BMP type-1A receptor) (BMPR-1A) (EC 2.7.11.30) (Activin receptor-like kinase 3) (ALK-3) (BMP-2/BMP-4 receptor) (Serine/threonine-protein kinase receptor R5) (SKR5) (CD antigen CD292) Mus musculus (Mouse) angiogenesis [GO:0001525]; anterior/posterior pattern specification [GO:0009952]; atrioventricular node cell development [GO:0060928]; atrioventricular valve development [GO:0003171]; BMP signaling pathway [GO:0030509]; BMP signaling pathway involved in heart development [GO:0061312]; cardiac conduction system development [GO:0003161]; cardiac right ventricle morphogenesis [GO:0003215]; cartilage development [GO:0051216]; cellular response to BMP stimulus [GO:0071773]; cellular response to growth factor stimulus [GO:0071363]; central nervous system neuron differentiation [GO:0021953]; chondrocyte differentiation [GO:0002062]; developmental growth [GO:0048589]; dorsal aorta morphogenesis [GO:0035912]; dorsal/ventral axis specification [GO:0009950]; dorsal/ventral pattern formation [GO:0009953]; ectoderm development [GO:0007398]; embryonic digit morphogenesis [GO:0042733]; embryonic morphogenesis [GO:0048598]; embryonic organ development [GO:0048568]; endocardial cushion formation [GO:0003272]; endocardial cushion morphogenesis [GO:0003203]; endoderm development [GO:0007492]; epithelial cell proliferation [GO:0050673]; fibrous ring of heart morphogenesis [GO:1905285]; heart development [GO:0007507]; heart formation [GO:0060914]; heart morphogenesis [GO:0003007]; hindlimb morphogenesis [GO:0035137]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; lateral mesoderm development [GO:0048368]; lung development [GO:0030324]; mesendoderm development [GO:0048382]; mesoderm formation [GO:0001707]; mitral valve morphogenesis [GO:0003183]; Mullerian duct regression [GO:0001880]; negative regulation of gene expression [GO:0010629]; negative regulation of muscle cell differentiation [GO:0051148]; negative regulation of neurogenesis [GO:0050768]; negative regulation of smooth muscle cell migration [GO:0014912]; nervous system development [GO:0007399]; neural crest cell development [GO:0014032]; neural plate mediolateral regionalization [GO:0021998]; neural plate pattern specification [GO:0060896]; odontogenesis of dentin-containing tooth [GO:0042475]; osteoblast differentiation [GO:0001649]; outflow tract morphogenesis [GO:0003151]; outflow tract septum morphogenesis [GO:0003148]; paraxial mesoderm development [GO:0048339]; paraxial mesoderm structural organization [GO:0048352]; pattern specification process [GO:0007389]; pharyngeal arch artery morphogenesis [GO:0061626]; pituitary gland development [GO:0021983]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cardiac ventricle development [GO:1904414]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of gene expression [GO:0010628]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta2 production [GO:0032915]; positive regulation of vascular associated smooth muscle cell proliferation [GO:1904707]; protein phosphorylation [GO:0006468]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of cellular senescence [GO:2000772]; regulation of lateral mesodermal cell fate specification [GO:0048378]; roof of mouth development [GO:0060021]; somatic stem cell population maintenance [GO:0035019]; somitogenesis [GO:0001756]; tricuspid valve morphogenesis [GO:0003186]; ventricular compact myocardium morphogenesis [GO:0003223]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222] GO:0001525; GO:0001649; GO:0001701; GO:0001707; GO:0001756; GO:0001880; GO:0002053; GO:0002062; GO:0003007; GO:0003148; GO:0003151; GO:0003161; GO:0003171; GO:0003183; GO:0003186; GO:0003203; GO:0003215; GO:0003222; GO:0003223; GO:0003272; GO:0004674; GO:0005025; GO:0005524; GO:0005886; GO:0005901; GO:0006468; GO:0006955; GO:0007389; GO:0007398; GO:0007399; GO:0007492; GO:0007507; GO:0009897; GO:0009950; GO:0009952; GO:0009953; GO:0009986; GO:0010628; GO:0010629; GO:0010862; GO:0014032; GO:0014912; GO:0019211; GO:0021953; GO:0021983; GO:0021998; GO:0030324; GO:0030425; GO:0030501; GO:0030509; GO:0032915; GO:0035019; GO:0035137; GO:0035912; GO:0036122; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0043235; GO:0043539; GO:0045669; GO:0045944; GO:0046332; GO:0046872; GO:0048339; GO:0048352; GO:0048368; GO:0048378; GO:0048382; GO:0048568; GO:0048589; GO:0048598; GO:0050673; GO:0050679; GO:0050768; GO:0051148; GO:0051216; GO:0060021; GO:0060043; GO:0060045; GO:0060391; GO:0060412; GO:0060896; GO:0060914; GO:0060928; GO:0061312; GO:0061626; GO:0071363; GO:0071773; GO:0098821; GO:0140537; GO:1902895; GO:1904414; GO:1904707; GO:1905285; GO:2000772 21765 XM_044325402.1 1 0 0 0 16 NA NA NA NA NA NA 21766 XM_044318991.1 8 0 20 5 143 NA NA NA NA NA NA 21767 XM_044311524.1 73 0 0 0 0 Q9VBW3 7.13e-78 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 21768 XM_044315690.1 0 0 0 0 7 NA NA NA NA NA NA 21769 XR_003825073.2 0 0 12 0 0 NA NA NA NA NA NA 21770 XM_029344980.2 65 317 13 317 0 Q8NF64 5.59e-140 Zinc finger MIZ domain-containing protein 2 (PIAS-like protein Zimp7) Homo sapiens (Human) positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0005634; GO:0005654; GO:0005739; GO:0006357; GO:0008270; GO:0030374; GO:0043596; GO:0045944 21771 XM_044309075.1 46 11 17 2 13 NA NA NA NA NA NA 21772 XM_029331552.2 2837 3161 1492 1515 2248 Q5RAM2 3.89e-58 Estrogen-related receptor gamma (Estrogen receptor-related protein 3) (Nuclear receptor subfamily 3 group B member 3) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) regulation of DNA-templated transcription [GO:0006355]; retinoic acid receptor signaling pathway [GO:0048384] GO:0003707; GO:0004879; GO:0005496; GO:0005654; GO:0006355; GO:0008270; GO:0043565; GO:0048384 21773 XM_044312125.1 35 23 15 0 258 NA NA NA NA NA NA 21774 XM_044316110.1 5 1 26 13 0 NA NA NA NA NA NA 21775 XM_044311724.1 0 0 220 0 366 NA NA NA NA NA NA 21776 XM_029338535.2 42 38 12 9 9 NA NA NA NA NA NA 21777 XM_044320807.1 0 0 0 8 0 NA NA NA NA NA NA 21778 XM_044308338.1 18 0 4 19 0 NA NA NA NA NA NA 21779 XR_006394762.1 304 130 299 308 449 NA NA NA NA NA NA 21780 XM_029353730.2 28 0 0 4 34 NA NA NA NA NA NA 21781 XM_029336548.2 1564 1460 1097 1175 739 Q0IIH8 2.95e-123 Ubiquitin carboxyl-terminal hydrolase MINDY-3 (EC 3.4.19.12) (Deubiquitinating enzyme MINDY-3) (Protein CARP) Bos taurus (Bovine) apoptotic process [GO:0006915]; protein K48-linked deubiquitination [GO:0071108] GO:0004843; GO:0005654; GO:0006915; GO:0031965; GO:0071108; GO:1990380 21782 XM_044325378.1 0 1 43 0 92 Q9Z351 3.54e-68 Potassium voltage-gated channel subfamily KQT member 2 (KQT-like 2) (Potassium channel subunit alpha KvLQT2) (Voltage-gated potassium channel subunit Kv7.2) Mus musculus (Mouse) potassium ion transmembrane transport [GO:0071805]; regulation of ion transmembrane transport [GO:0034765]; transmission of nerve impulse [GO:0019226] GO:0005244; GO:0005249; GO:0005251; GO:0005516; GO:0005886; GO:0008076; GO:0009986; GO:0016020; GO:0019226; GO:0030506; GO:0032991; GO:0033268; GO:0034765; GO:0043194; GO:0047485; GO:0071805 21783 XM_029333916.2 0 262 0 0 0 Q09499 0 Serine/threonine-protein kinase/endoribonuclease ire-1 (Inositol-requiring protein 2) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)] Caenorhabditis elegans endoplasmic reticulum unfolded protein response [GO:0030968]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; IRE1-mediated unfolded protein response [GO:0036498]; mRNA cleavage involved in mRNA processing [GO:0098787]; nematode larval development [GO:0002119]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response [GO:0006990]; protein phosphorylation [GO:0006468]; response to endoplasmic reticulum stress [GO:0034976]; response to hypoxia [GO:0001666]; response to topologically incorrect protein [GO:0035966] GO:0001666; GO:0002119; GO:0004521; GO:0004674; GO:0005524; GO:0005789; GO:0006468; GO:0006990; GO:0030968; GO:0034976; GO:0035966; GO:0036498; GO:0051082; GO:0070059; GO:0090305; GO:0098787; GO:0106310; GO:1990440; GO:1990604 21784 XR_006391958.1 0 6 0 0 0 NA NA NA NA NA NA 21785 XM_029347672.2 68 49 36 80 75 Q0P5B1 2.16e-26 Peroxisomal membrane protein PEX13 (Peroxin-13) Bos taurus (Bovine) cerebral cortex cell migration [GO:0021795]; fatty acid alpha-oxidation [GO:0001561]; locomotory behavior [GO:0007626]; microtubule-based peroxisome localization [GO:0060152]; neuron migration [GO:0001764]; protein import into peroxisome matrix, docking [GO:0016560]; suckling behavior [GO:0001967] GO:0001561; GO:0001764; GO:0001967; GO:0005778; GO:0007626; GO:0008320; GO:0016560; GO:0021795; GO:0060152; GO:1990429 21786 XM_029332298.2 0 0 0 0 20 Q66JZ4 3.98e-65 T-cell activation inhibitor, mitochondrial (Tolerance associated gene-1 protein) (TOAG-1) Mus musculus (Mouse) NA GO:0005739 21787 XR_006394509.1 293 194 125 278 350 NA NA NA NA NA NA 21788 XR_006393173.1 10 2 6 7 6 NA NA NA NA NA NA 21789 XM_044313264.1 245 85 89 193 165 A0A1L8FDW4 3.29e-49 Peroxisomal targeting signal 1 receptor (PTS1 receptor) (PTS1R) (PTS1-BP) (Peroxin-5) Xenopus laevis (African clawed frog) pexophagy [GO:0000425]; protein import into peroxisome matrix, receptor recycling [GO:0016562]; protein import into peroxisome matrix, substrate release [GO:0044721]; protein import into peroxisome matrix, translocation [GO:0016561] GO:0000425; GO:0005052; GO:0005782; GO:0005829; GO:0016561; GO:0016562; GO:0044721; GO:0140597 21790 XM_029342576.2 293 351 246 146 96 NA NA NA NA NA NA 21791 XM_029330592.2 0 19 40 15 22 O95395 8.2e-63 Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 (EC 2.4.1.102) (EC 2.4.1.148) (EC 2.4.1.150) (C2GnT-mucin type) (C2GnT-M) (hC2GnT-M) (Core 2/core 4 beta-1,6-N-acetylglucosaminyltransferase) (C2/4GnT) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; intestinal absorption [GO:0050892]; kidney morphogenesis [GO:0060993]; O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493]; tissue morphogenesis [GO:0048729] GO:0000139; GO:0003829; GO:0005975; GO:0006493; GO:0008109; GO:0008375; GO:0016020; GO:0016266; GO:0048729; GO:0050892; GO:0060993; GO:0070062; GO:0106325; GO:0106326 21792 XM_044321619.1 0 0 0 41 0 Q3URQ0 5.57e-58 Testis-expressed protein 10 Mus musculus (Mouse) NA GO:0005634; GO:0005654; GO:0005730; GO:0005739; GO:0071339 21793 XM_044308334.1 6763 4765 3591 10686 9134 NA NA NA NA NA NA 21794 XM_044328968.1 269 219 76 286 523 NA NA NA NA NA NA 21795 XM_044320252.1 7 107 26 13 52 NA NA NA NA NA NA 21796 XM_044308296.1 70 43 74 1 76 NA NA NA NA NA NA 21797 XR_006391530.1 16 0 1 12 49 NA NA NA NA NA NA 21798 XM_029330689.2 13 4 4 28 22 NA NA NA NA NA NA 21799 XM_044324297.1 344 464 410 546 818 Q80T79 2.16e-38 CUB and sushi domain-containing protein 3 (CUB and sushi multiple domains protein 3) Mus musculus (Mouse) negative regulation of complement activation, classical pathway [GO:0045959]; regulation of dendrite development [GO:0050773] GO:0005615; GO:0005886; GO:0045959; GO:0050773 21800 XM_044324297.1 344 464 410 546 818 Q80T79 1.99e-35 CUB and sushi domain-containing protein 3 (CUB and sushi multiple domains protein 3) Mus musculus (Mouse) negative regulation of complement activation, classical pathway [GO:0045959]; regulation of dendrite development [GO:0050773] GO:0005615; GO:0005886; GO:0045959; GO:0050773 21801 XM_044324297.1 344 464 410 546 818 Q80T79 6.54e-28 CUB and sushi domain-containing protein 3 (CUB and sushi multiple domains protein 3) Mus musculus (Mouse) negative regulation of complement activation, classical pathway [GO:0045959]; regulation of dendrite development [GO:0050773] GO:0005615; GO:0005886; GO:0045959; GO:0050773 21802 XM_044324297.1 344 464 410 546 818 Q80T79 7.48e-27 CUB and sushi domain-containing protein 3 (CUB and sushi multiple domains protein 3) Mus musculus (Mouse) negative regulation of complement activation, classical pathway [GO:0045959]; regulation of dendrite development [GO:0050773] GO:0005615; GO:0005886; GO:0045959; GO:0050773 21803 XM_044324297.1 344 464 410 546 818 Q80T79 7.48e-21 CUB and sushi domain-containing protein 3 (CUB and sushi multiple domains protein 3) Mus musculus (Mouse) negative regulation of complement activation, classical pathway [GO:0045959]; regulation of dendrite development [GO:0050773] GO:0005615; GO:0005886; GO:0045959; GO:0050773 21804 XM_029357393.2 212 228 202 315 205 Q58DM4 1.54e-86 DNA oxidative demethylase ALKBH2 (EC 1.14.11.33) (Alkylated DNA repair protein alkB homolog 2) (Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2) Bos taurus (Bovine) DNA dealkylation involved in DNA repair [GO:0006307]; oxidative DNA demethylation [GO:0035511] GO:0000182; GO:0005654; GO:0005730; GO:0006307; GO:0008198; GO:0035511; GO:0035516; GO:0043734; GO:0051747 21805 XM_029340566.2 30 48 35 53 37 NA NA NA NA NA NA 21806 XM_029343835.2 67 7 3 113 555 NA NA NA NA NA NA 21807 XM_044316594.1 911 185 747 1299 1201 Q8BWC0 3.09e-161 Two pore channel protein 2 (Two pore calcium channel protein 2) (Voltage-dependent calcium channel protein TPC2) Mus musculus (Mouse) calcium-mediated signaling [GO:0019722]; cellular calcium ion homeostasis [GO:0006874]; endocytosis involved in viral entry into host cell [GO:0075509]; endosome to lysosome transport of low-density lipoprotein particle [GO:0090117]; intracellular pH reduction [GO:0051452]; lysosome organization [GO:0007040]; negative regulation of developmental pigmentation [GO:0048086]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of autophagy [GO:0010506]; regulation of exocytosis [GO:0017157]; regulation of ion transmembrane transport [GO:0034765]; release of sequestered calcium ion into cytosol [GO:0051209]; response to vitamin D [GO:0033280]; smooth muscle contraction [GO:0006939]; sodium ion transmembrane transport [GO:0035725] GO:0005245; GO:0005262; GO:0005764; GO:0005765; GO:0005829; GO:0006874; GO:0006939; GO:0007040; GO:0010008; GO:0010506; GO:0015280; GO:0017157; GO:0019065; GO:0019722; GO:0019901; GO:0031902; GO:0033162; GO:0033280; GO:0034765; GO:0035725; GO:0036020; GO:0042802; GO:0048086; GO:0051209; GO:0051452; GO:0072345; GO:0075509; GO:0080025; GO:0090117; GO:0097682 21808 XM_044324429.1 9 51 14 60 105 NA NA NA NA NA NA 21809 XM_044319623.1 248 152 139 176 124 Q9DBQ7 6.33e-89 Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin-binding protein PACE-1) (SCY1-like protein 3) Mus musculus (Mouse) inflammatory response [GO:0006954]; neuron development [GO:0048666]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; spinal cord motor neuron differentiation [GO:0021522] GO:0000139; GO:0004672; GO:0005524; GO:0005737; GO:0005794; GO:0006468; GO:0006954; GO:0008104; GO:0021522; GO:0030027; GO:0042802; GO:0048666 21810 XM_044307851.1 0 0 0 0 90 NA NA NA NA NA NA 21811 XM_029335220.2 7188 4451 4695 5650 3712 Q95029 5.92e-128 Cathepsin L (EC 3.4.22.15) (Cysteine proteinase 1) [Cleaved into: Cathepsin L heavy chain; Cathepsin L light chain] Drosophila melanogaster (Fruit fly) digestion [GO:0007586]; immune response [GO:0006955]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603] GO:0004197; GO:0005615; GO:0005764; GO:0006508; GO:0006955; GO:0007586; GO:0008233; GO:0008234; GO:0045169; GO:0051603 21812 XM_029341873.2 1444 616 626 877 638 Q95J53 5.64e-87 BTB/POZ domain-containing protein 16 Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA NA 21813 XM_044310292.1 4 53 5 92 31 NA NA NA NA NA NA 21814 XM_029331256.2 55 128 3 59 66 O60476 0 Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB (EC 3.2.1.113) (Mannosidase alpha class 1A member 2) (Processing alpha-1,2-mannosidase IB) (Alpha-1,2-mannosidase IB) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; Golgi apparatus mannose trimming [GO:1904381]; lung alveolus development [GO:0048286]; N-glycan processing [GO:0006491]; protein glycosylation [GO:0006486]; respiratory gaseous exchange by respiratory system [GO:0007585] GO:0000139; GO:0004571; GO:0005509; GO:0005783; GO:0005794; GO:0005975; GO:0006486; GO:0006491; GO:0007585; GO:0016020; GO:0048286; GO:0070062; GO:1904381 21815 XM_044327146.1 68 38 38 85 272 NA NA NA NA NA NA 21816 XM_044324205.1 29 0 0 0 33 Q8C206 6.35e-26 G-protein coupled receptor 157 Mus musculus (Mouse) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; circadian behavior [GO:0048512]; G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; radial glial cell differentiation [GO:0060019] GO:0004930; GO:0005886; GO:0007166; GO:0007186; GO:0007189; GO:0048512; GO:0051482; GO:0060019; GO:0060170 21817 XM_044308677.1 1259 718 757 1216 1350 Q99MZ3 4.71e-60 Carbohydrate-responsive element-binding protein (ChREBP) (MLX interactor) (MLX-interacting protein-like) (Williams-Beuren syndrome chromosomal region 14 protein homolog) Mus musculus (Mouse) cellular response to glucose stimulus [GO:0071333]; energy homeostasis [GO:0097009]; fatty acid homeostasis [GO:0055089]; glucose homeostasis [GO:0042593]; glucose mediated signaling pathway [GO:0010255]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of fatty acid biosynthetic process [GO:0045723]; positive regulation of glycolytic process [GO:0045821]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of glycolytic process [GO:0006110]; regulation of transcription by RNA polymerase II [GO:0006357]; response to glucose [GO:0009749] GO:0000122; GO:0000978; GO:0000981; GO:0001227; GO:0003677; GO:0003700; GO:0005634; GO:0005654; GO:0005667; GO:0005737; GO:0005829; GO:0006110; GO:0006357; GO:0008284; GO:0009749; GO:0010255; GO:0019901; GO:0033137; GO:0035538; GO:0042593; GO:0043565; GO:0045723; GO:0045821; GO:0045892; GO:0045893; GO:0045944; GO:0046889; GO:0046982; GO:0055089; GO:0061629; GO:0071333; GO:0090324; GO:0097009 21818 XM_044308677.1 1259 718 757 1216 1350 Q99MZ3 2.8e-29 Carbohydrate-responsive element-binding protein (ChREBP) (MLX interactor) (MLX-interacting protein-like) (Williams-Beuren syndrome chromosomal region 14 protein homolog) Mus musculus (Mouse) cellular response to glucose stimulus [GO:0071333]; energy homeostasis [GO:0097009]; fatty acid homeostasis [GO:0055089]; glucose homeostasis [GO:0042593]; glucose mediated signaling pathway [GO:0010255]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of fatty acid biosynthetic process [GO:0045723]; positive regulation of glycolytic process [GO:0045821]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of glycolytic process [GO:0006110]; regulation of transcription by RNA polymerase II [GO:0006357]; response to glucose [GO:0009749] GO:0000122; GO:0000978; GO:0000981; GO:0001227; GO:0003677; GO:0003700; GO:0005634; GO:0005654; GO:0005667; GO:0005737; GO:0005829; GO:0006110; GO:0006357; GO:0008284; GO:0009749; GO:0010255; GO:0019901; GO:0033137; GO:0035538; GO:0042593; GO:0043565; GO:0045723; GO:0045821; GO:0045892; GO:0045893; GO:0045944; GO:0046889; GO:0046982; GO:0055089; GO:0061629; GO:0071333; GO:0090324; GO:0097009 21819 XM_044323826.1 59 35 0 0 0 Q15434 4.98e-77 RNA-binding motif, single-stranded-interacting protein 2 (Suppressor of CDC2 with RNA-binding motif 3) Homo sapiens (Human) RNA processing [GO:0006396] GO:0003723; GO:0003730; GO:0005634; GO:0005829; GO:0006396; GO:0008143; GO:0008266; GO:1990904 21820 XM_029341585.2 1045 728 617 742 1277 Q8R3N1 4.4e-149 Nucleolar protein 14 (Nucleolar complex protein 14) Mus musculus (Mouse) maturation of SSU-rRNA [GO:0030490]; ribosomal small subunit biogenesis [GO:0042274] GO:0005654; GO:0005730; GO:0019899; GO:0030490; GO:0030515; GO:0030692; GO:0032040; GO:0042274 21821 XM_029335458.2 489 424 235 517 456 NA NA NA NA NA NA 21822 XM_044320314.1 40 39 28 43 62 Q95SX7 4.36e-28 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 21823 XM_044325193.1 0 9 4 0 0 P09917 9.72e-85 Polyunsaturated fatty acid 5-lipoxygenase (EC 1.13.11.-) (Arachidonate 5-lipoxygenase) (5-LO) (5-lipoxygenase) (EC 1.13.11.34) Homo sapiens (Human) arachidonic acid metabolic process [GO:0019369]; dendritic cell migration [GO:0036336]; glucose homeostasis [GO:0042593]; hepoxilin biosynthetic process [GO:0051122]; humoral immune response [GO:0006959]; leukocyte chemotaxis involved in inflammatory response [GO:0002232]; leukocyte migration involved in inflammatory response [GO:0002523]; leukotriene A4 biosynthetic process [GO:1901753]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; leukotriene production involved in inflammatory response [GO:0002540]; linoleic acid metabolic process [GO:0043651]; lipid oxidation [GO:0034440]; lipoxin biosynthetic process [GO:2001301]; lipoxygenase pathway [GO:0019372]; long-chain fatty acid biosynthetic process [GO:0042759]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of inflammatory response [GO:0050728]; negative regulation of response to endoplasmic reticulum stress [GO:1903573]; negative regulation of sprouting angiogenesis [GO:1903671]; negative regulation of vascular wound healing [GO:0061044]; negative regulation of wound healing [GO:0061045]; positive regulation of bone mineralization [GO:0030501]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; regulation of cellular response to oxidative stress [GO:1900407]; regulation of cytokine production involved in inflammatory response [GO:1900015]; regulation of fat cell differentiation [GO:0045598]; regulation of inflammatory response [GO:0050727]; regulation of inflammatory response to wounding [GO:0106014]; regulation of insulin secretion [GO:0050796]; regulation of reactive oxygen species biosynthetic process [GO:1903426] GO:0001937; GO:0002232; GO:0002523; GO:0002540; GO:0004051; GO:0004052; GO:0005506; GO:0005576; GO:0005615; GO:0005635; GO:0005641; GO:0005654; GO:0005829; GO:0006691; GO:0006959; GO:0016363; GO:0016525; GO:0016702; GO:0016787; GO:0019369; GO:0019370; GO:0019372; GO:0030501; GO:0031965; GO:0034440; GO:0034774; GO:0036336; GO:0036403; GO:0042593; GO:0042759; GO:0043651; GO:0045598; GO:0048471; GO:0050727; GO:0050728; GO:0050796; GO:0051122; GO:0061044; GO:0061045; GO:0106014; GO:1900015; GO:1900407; GO:1901753; GO:1903426; GO:1903573; GO:1903671; GO:1904813; GO:1904999; GO:2001301 21824 XM_029352626.2 317 466 367 665 175 NA NA NA NA NA NA 21825 XR_006392525.1 0 19 0 0 1 NA NA NA NA NA NA 21826 XM_029338994.2 6942 3315 3628 4127 3639 P24367 2.28e-97 Peptidyl-prolyl cis-trans isomerase B (PPIase B) (EC 5.2.1.8) (Cyclophilin B) (Rotamase B) (S-cyclophilin) (SCYLP) Gallus gallus (Chicken) chaperone-mediated protein folding [GO:0061077]; negative regulation of collagen fibril organization [GO:1904027]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413] GO:0000413; GO:0003755; GO:0005737; GO:0005788; GO:0006457; GO:0016018; GO:0032991; GO:0042470; GO:0043231; GO:0061077; GO:1904027 21827 XM_044308972.1 29 6 13 35 45 NA NA NA NA NA NA 21828 XM_044319711.1 865 568 398 678 333 Q93Z30 2.6e-26 NA NA NA NA 21829 XM_044323182.1 85 92 32 58 80 NA NA NA NA NA NA 21830 XM_044311101.1 8 6 24 22 0 Q3UQ28 5.54e-33 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 21831 XM_044311101.1 8 6 24 22 0 Q3UQ28 1.28e-26 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 21832 XM_029346855.2 1789 1014 948 2468 3675 Q9EPR4 4.39e-178 Solute carrier family 23 member 2 (Na(+)/L-ascorbic acid transporter 2) (Sodium-dependent vitamin C transporter 2) (SVCT-2) (mSVCT2) (Yolk sac permease-like molecule 2) Mus musculus (Mouse) cellular response to ethanol [GO:0071361]; L-ascorbic acid metabolic process [GO:0019852]; L-ascorbic acid transmembrane transport [GO:0015882]; negative regulation of neuron death [GO:1901215]; positive regulation of dendrite extension [GO:1903861]; response to oxidative stress [GO:0006979] GO:0005737; GO:0005886; GO:0006979; GO:0008520; GO:0009925; GO:0015229; GO:0015882; GO:0016323; GO:0016324; GO:0019852; GO:0071361; GO:1901215; GO:1903861 21833 XR_006392885.1 41 2 25 5 151 NA NA NA NA NA NA 21834 XM_029336101.2 15087 11321 6962 10428 6173 Q0VH32 4e-29 Max-binding protein MNT (Myc antagonist MNT) Xenopus laevis (African clawed frog) NA GO:0003677; GO:0005634; GO:0046983 21835 XM_044314163.1 418 217 105 250 320 NA NA NA NA NA NA 21836 XM_029356327.2 716 692 472 735 740 Q5FW46 2.56e-69 Atos homolog protein A Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005634 21837 XM_029356327.2 716 692 472 735 740 Q5FW46 1.16e-29 Atos homolog protein A Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005634 21838 XR_006397500.1 0 0 21 0 0 NA NA NA NA NA NA 21839 XM_044311224.1 516 258 174 360 373 Q96PY6 2.34e-142 Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase 1) (NimA-related protein kinase 1) (Renal carcinoma antigen NY-REN-55) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; cilium assembly [GO:0060271]; protein phosphorylation [GO:0006468] GO:0000242; GO:0004672; GO:0004674; GO:0004713; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0005829; GO:0006468; GO:0007049; GO:0016301; GO:0034451; GO:0046872; GO:0051301; GO:0060271; GO:0071889; GO:0106310 21840 XM_044319922.1 0 0 26 0 0 Q5XJN2 8.8e-49 Gamma-interferon-inducible lysosomal thiol reductase (EC 1.8.-.-) (Gamma-interferon-inducible protein IP-30) Danio rerio (Zebrafish) (Brachydanio rerio) immune system process [GO:0002376] GO:0002376; GO:0005576; GO:0005764; GO:0016491; GO:0016667; GO:0016671; GO:0047134 21841 XM_029335811.2 42 33 40 24 101 NA NA NA NA NA NA 21842 XM_044325952.1 3098 1703 1197 1764 2009 Q91W86 0 Vacuolar protein sorting-associated protein 11 homolog Mus musculus (Mouse) autophagy [GO:0006914]; endosomal vesicle fusion [GO:0034058]; endosome organization [GO:0007032]; endosome to lysosome transport [GO:0008333]; intracellular protein transport [GO:0006886]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; organelle fusion [GO:0048284]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of protein catabolic process [GO:0045732]; protein ubiquitination [GO:0016567]; regulation of organelle assembly [GO:1902115]; toxin transport [GO:1901998]; vacuole organization [GO:0007033]; vesicle docking involved in exocytosis [GO:0006904] GO:0000166; GO:0005764; GO:0005765; GO:0005768; GO:0005769; GO:0005770; GO:0005776; GO:0005884; GO:0006886; GO:0006904; GO:0006914; GO:0007032; GO:0007033; GO:0008333; GO:0016567; GO:0019904; GO:0019905; GO:0030136; GO:0030139; GO:0030674; GO:0030897; GO:0031902; GO:0033147; GO:0033263; GO:0034058; GO:0045732; GO:0046872; GO:0048284; GO:0048786; GO:0061630; GO:1901998; GO:1902115; GO:2000643 21843 XM_029355986.2 0 40 19 0 0 NA NA NA NA NA NA 21844 XR_006394036.1 7 9 8 0 3 NA NA NA NA NA NA 21845 XM_029356639.2 1389 953 555 883 546 NA NA NA NA NA NA 21846 XM_044319483.1 99 7 22 35 55 NA NA NA NA NA NA 21847 XM_029341561.2 754 0 325 896 587 Q9P107 6.52e-98 GEM-interacting protein (GMIP) Homo sapiens (Human) activation of GTPase activity [GO:0090630]; intracellular signal transduction [GO:0035556]; negative regulation of GTPase activity [GO:0034260]; regulation of small GTPase mediated signal transduction [GO:0051056] GO:0005096; GO:0005654; GO:0005829; GO:0005886; GO:0034260; GO:0035556; GO:0046872; GO:0051056; GO:0090630 21848 XM_044317039.1 192 140 84 129 129 Q9CXC3 1.41e-52 Mitochondrial genome maintenance exonuclease 1 (EC 3.1.-.-) Mus musculus (Mouse) mitochondrial DNA repair [GO:0043504]; mitochondrial DNA replication [GO:0006264]; mitochondrial genome maintenance [GO:0000002] GO:0000002; GO:0005739; GO:0006264; GO:0008297; GO:0043504 21849 XM_029338773.2 38 3 7 126 155 D9IQ16 1.12e-33 Galaxin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 21850 XM_029338773.2 38 3 7 126 155 D9IQ16 1.42e-32 Galaxin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 21851 XM_029338773.2 38 3 7 126 155 D9IQ16 4.77e-31 Galaxin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 21852 XM_029338773.2 38 3 7 126 155 D9IQ16 2.41e-23 Galaxin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 21853 XM_029338773.2 38 3 7 126 155 D9IQ16 8.4e-21 Galaxin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 21854 XM_029332118.2 1379 648 608 1236 1011 Q91Y80 7.92e-39 SH3 domain-binding protein 5 (SH3BP-5) (Vascular endothelial cell-specific protein 18) Rattus norvegicus (Rat) intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein tyrosine kinase activity [GO:0061099] GO:0004860; GO:0005085; GO:0005737; GO:0005739; GO:0006469; GO:0007254; GO:0017124; GO:0030659; GO:0035556; GO:0061099 21855 XM_029355292.2 666 416 260 706 651 P43138 4.03e-112 DNA-(apurinic or apyrimidinic site) endonuclease (EC 3.1.11.2) (APEX nuclease) (APEN) (Apurinic-apyrimidinic endonuclease 1) (AP endonuclease 1) (REF-1) (Redox factor-1) [Cleaved into: DNA-(apurinic or apyrimidinic site) endonuclease, mitochondrial] Rattus norvegicus (Rat) aging [GO:0007568]; base-excision repair [GO:0006284]; cell redox homeostasis [GO:0045454]; cellular response to cAMP [GO:0071320]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to organonitrogen compound [GO:0071417]; cellular response to peptide hormone stimulus [GO:0071375]; DNA catabolic process, endonucleolytic [GO:0000737]; DNA demethylation [GO:0080111]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; negative regulation of smooth muscle cell migration [GO:0014912]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of mRNA stability [GO:0043488]; response to organonitrogen compound [GO:0010243]; response to xenobiotic stimulus [GO:0009410]; telomere maintenance [GO:0000723]; telomere maintenance via base-excision repair [GO:0097698] GO:0000723; GO:0000737; GO:0003677; GO:0003684; GO:0003691; GO:0003713; GO:0003723; GO:0003906; GO:0004519; GO:0004521; GO:0005634; GO:0005667; GO:0005730; GO:0005737; GO:0005739; GO:0005783; GO:0005813; GO:0006281; GO:0006284; GO:0006310; GO:0007568; GO:0008081; GO:0008296; GO:0008309; GO:0008311; GO:0008408; GO:0009410; GO:0010243; GO:0014912; GO:0016491; GO:0016607; GO:0016890; GO:0031490; GO:0042981; GO:0043488; GO:0044877; GO:0045454; GO:0045944; GO:0046872; GO:0048471; GO:0051059; GO:0052720; GO:0070301; GO:0071320; GO:0071375; GO:0071417; GO:0080111; GO:0090580; GO:0097698; GO:0140431; GO:1900087 21856 XM_029350010.2 0 0 0 0 8 NA NA NA NA NA NA 21857 XR_006391502.1 115 29 99 15 325 NA NA NA NA NA NA 21858 XM_044318049.1 81 48 87 54 111 Q54KA7 9.6e-23 Ankyrin repeat, PH and SEC7 domain containing protein secG Dictyostelium discoideum (Social amoeba) actin cytoskeleton organization [GO:0030036]; cell-substrate adhesion [GO:0031589]; chemotaxis [GO:0006935]; chemotaxis to cAMP [GO:0043327]; culmination involved in sorocarp development [GO:0031154]; regulation of ARF protein signal transduction [GO:0032012] GO:0005085; GO:0005764; GO:0005829; GO:0006935; GO:0030036; GO:0031154; GO:0031589; GO:0032012; GO:0043327 21859 XR_006397105.1 0 0 7 0 54 NA NA NA NA NA NA 21860 XM_044322475.1 0 0 24 0 7 C6KFA3 2.51e-36 Adhesion G-protein coupled receptor G6 (G-protein coupled receptor 126) [Cleaved into: ADGRG6 N-terminal fragment (ADGRG6-NTF); ADGRG6 C-terminal fragment (ADGRG6-CTF)] Danio rerio (Zebrafish) (Brachydanio rerio) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cAMP-mediated signaling [GO:0019933]; cell surface receptor signaling pathway [GO:0007166]; ear development [GO:0043583]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; heart trabecula formation [GO:0060347]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; myelination of posterior lateral line nerve axons [GO:0048932]; ossification [GO:0001503]; peripheral nervous system myelin formation [GO:0032290]; regulation of sprouting angiogenesis [GO:1903670]; Schwann cell differentiation [GO:0014037]; semicircular canal fusion [GO:0060879] GO:0001503; GO:0004930; GO:0005518; GO:0005886; GO:0007005; GO:0007166; GO:0007186; GO:0007189; GO:0007507; GO:0014037; GO:0019933; GO:0022011; GO:0032290; GO:0042552; GO:0043236; GO:0043583; GO:0048932; GO:0050840; GO:0060347; GO:0060879; GO:1903670 21861 XM_029332026.2 412 406 184 468 502 Q8BP00 9.07e-96 IQ calmodulin-binding motif-containing protein 1 Mus musculus (Mouse) cilium assembly [GO:0060271]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494] GO:0001750; GO:0005516; GO:0005654; GO:0005737; GO:0005813; GO:0005929; GO:0015630; GO:0019899; GO:0032391; GO:0045171; GO:0045494; GO:0048496; GO:0060271; GO:0072686 21862 XM_044323513.1 0 70 0 0 0 NA NA NA NA NA NA 21863 XR_006397653.1 3 8 0 5 9 NA NA NA NA NA NA 21864 XM_029339582.2 7 29 53 0 39 NA NA NA NA NA NA 21865 XM_044324275.1 198 134 153 268 365 Q8NDA2 7.85e-81 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 21866 XM_044324275.1 198 134 153 268 365 Q8NDA2 2.77e-62 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 21867 XM_044324275.1 198 134 153 268 365 Q8NDA2 3.06e-61 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 21868 XM_044324275.1 198 134 153 268 365 Q8NDA2 9.64e-56 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 21869 XM_044324275.1 198 134 153 268 365 Q8NDA2 4.05e-53 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 21870 XM_044324275.1 198 134 153 268 365 Q8NDA2 3.93e-48 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 21871 XM_044324275.1 198 134 153 268 365 Q8NDA2 2.04e-39 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 21872 XM_044323508.1 87 0 22 2 167 NA NA NA NA NA NA 21873 XM_044317228.1 53 49 20 0 0 O54991 5.78e-36 Contactin-associated protein 1 (Caspr) (Caspr1) (MHDNIV) (NCP1) (Neurexin IV) (Neurexin-4) (Paranodin) Mus musculus (Mouse) axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cytoskeleton organization [GO:0007010]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process [GO:0050905]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuronal action potential propagation [GO:0019227]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; postsynaptic density organization [GO:0097106]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; regulation of synapse maturation [GO:0090128] GO:0002175; GO:0005886; GO:0005918; GO:0007005; GO:0007010; GO:0007155; GO:0007409; GO:0016020; GO:0017124; GO:0019227; GO:0022010; GO:0022011; GO:0030424; GO:0030913; GO:0031175; GO:0033010; GO:0033270; GO:0042552; GO:0043209; GO:0048786; GO:0048812; GO:0050884; GO:0050885; GO:0050905; GO:0071205; GO:0090128; GO:0097106; GO:0098529; GO:0098978; GO:1990227 21874 XM_029346519.2 305 372 212 282 488 Q9NUP7 8.73e-102 tRNA:m(4)X modification enzyme TRM13 homolog (EC 2.1.1.225) (Coiled-coil domain-containing protein 76) Homo sapiens (Human) tRNA methylation [GO:0030488] GO:0008175; GO:0030488; GO:0046872; GO:0106050 21875 XM_044317695.1 26 6 15 3 49 NA NA NA NA NA NA 21876 XM_029345762.2 53 62 63 47 75 Q9SR22 5.29e-74 Pectin acetylesterase 5 (EC 3.1.1.-) Arabidopsis thaliana (Mouse-ear cress) cell wall organization [GO:0071555] GO:0005576; GO:0009505; GO:0052793; GO:0071555 21877 XR_006396535.1 1993 1172 733 1398 1050 Q14409 0 Glycerol kinase 3 (GK 3) (Glycerokinase 3) (EC 2.7.1.30) (ATP:glycerol 3-phosphotransferase 3) (Glycerol kinase 3 pseudogene) (Glycerol kinase, testis specific 1) Homo sapiens (Human) glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate biosynthetic process [GO:0046167]; phosphorylation [GO:0016310]; triglyceride metabolic process [GO:0006641] GO:0004370; GO:0005524; GO:0005739; GO:0005741; GO:0006071; GO:0006641; GO:0016310; GO:0016773; GO:0019563; GO:0046167 21878 XR_006397078.1 37 31 19 43 124 NA NA NA NA NA NA 21879 XR_006392851.1 0 0 1 0 25 NA NA NA NA NA NA 21880 XM_044323419.1 5 0 0 0 14 C0HL13 1.94e-24 Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin) Sus scrofa (Pig) coronary artery morphogenesis [GO:0060982]; folate import across plasma membrane [GO:1904447]; male gonad development [GO:0008584]; metal ion transport [GO:0030001]; negative regulation of BMP signaling pathway [GO:0030514]; neural tube closure [GO:0001843]; neuron projection arborization [GO:0140058]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of lysosomal protein catabolic process [GO:1905167]; positive regulation of neurogenesis [GO:0050769]; positive regulation of oligodendrocyte progenitor proliferation [GO:0070447]; pulmonary artery morphogenesis [GO:0061156]; receptor-mediated endocytosis [GO:0006898]; secondary heart field specification [GO:0003139]; sensory perception of sound [GO:0007605]; vagina development [GO:0060068]; ventricular compact myocardium morphogenesis [GO:0003223] GO:0001843; GO:0003139; GO:0003148; GO:0003223; GO:0005509; GO:0005905; GO:0006898; GO:0007605; GO:0008584; GO:0009897; GO:0016324; GO:0017124; GO:0030001; GO:0030424; GO:0030425; GO:0030514; GO:0031526; GO:0031904; GO:0043235; GO:0050769; GO:0051087; GO:0060068; GO:0060982; GO:0061156; GO:0070447; GO:0140058; GO:1904447; GO:1905167 21881 XR_003823161.2 3 277 130 278 42 NA NA NA NA NA NA 21882 XM_044322590.1 1601 269 584 1612 848 Q9WUA2 0 Phenylalanine--tRNA ligase beta subunit (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase beta subunit) (PheRS) Mus musculus (Mouse) phenylalanyl-tRNA aminoacylation [GO:0006432]; protein heterotetramerization [GO:0051290] GO:0000287; GO:0003723; GO:0004826; GO:0005524; GO:0006432; GO:0009328; GO:0051290 21883 XM_044322723.1 13 12 14 195 35 NA NA NA NA NA NA 21884 XM_029349184.2 61 71 76 53 44 NA NA NA NA NA NA 21885 XM_029347186.2 627 258 414 674 431 Q6NRT5 0 COP9 signalosome complex subunit 1 (Signalosome subunit 1) Xenopus laevis (African clawed frog) NA GO:0005737; GO:0008180 21886 XR_006396211.1 31 47 26 18 36 P0C0R5 1.23e-30 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) Rattus norvegicus (Rat) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006623; GO:0010506; GO:0015630; GO:0016236; GO:0016241; GO:0030242; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 21887 XR_006396211.1 31 47 26 18 36 P0C0R5 1.23e-30 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) Rattus norvegicus (Rat) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006623; GO:0010506; GO:0015630; GO:0016236; GO:0016241; GO:0030242; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 21888 XM_044314732.1 0 0 0 926 310 Q7RTR2 1.29e-68 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 21889 XM_044314732.1 0 0 0 926 310 Q7RTR2 1.75e-68 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 21890 XM_044314732.1 0 0 0 926 310 Q7RTR2 2.21e-56 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 21891 XM_044314732.1 0 0 0 926 310 Q7RTR2 2.24e-43 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 21892 XM_029343954.2 330 142 297 317 375 P91660 0 Probable multidrug resistance-associated protein lethal(2)03659 (Wunen region A protein) Drosophila melanogaster (Fruit fly) organic anion transport [GO:0015711]; transmembrane transport [GO:0055085] GO:0005524; GO:0008514; GO:0015562; GO:0015711; GO:0016020; GO:0016887; GO:0042626; GO:0055085; GO:0140359 21893 XR_006397335.1 800 352 254 348 358 NA NA NA NA NA NA 21894 XR_006393963.1 420 197 311 377 1086 NA NA NA NA NA NA 21895 XM_044327492.1 68 45 0 0 96 NA NA NA NA NA NA 21896 XM_044315926.1 80 26 22 12 30 NA NA NA NA NA NA 21897 XM_029350755.2 44 50 17 225 87 P51029 3.28e-71 Protein Wnt-8b Danio rerio (Zebrafish) (Brachydanio rerio) canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; commissural neuron axon guidance [GO:0071679]; embryonic pattern specification [GO:0009880]; eye development [GO:0001654]; eye field cell fate commitment involved in camera-type eye formation [GO:0060898]; forebrain development [GO:0030900]; forebrain neuron differentiation [GO:0021879]; hypothalamus development [GO:0021854]; negative regulation of anterior neural cell fate commitment of the neural plate by Wnt signaling pathway [GO:0022002]; neuron differentiation [GO:0030182]; otic placode formation [GO:0043049]; sensory epithelium regeneration [GO:0070654] GO:0001654; GO:0005109; GO:0005125; GO:0005615; GO:0009880; GO:0021854; GO:0021879; GO:0022002; GO:0030182; GO:0030900; GO:0043049; GO:0045165; GO:0060070; GO:0060898; GO:0070654; GO:0071679 21898 XM_029344905.2 191 164 117 140 112 Q5R8X9 3.27e-68 Protein AMN1 homolog Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA NA 21899 XM_029334825.2 1889 2271 872 2249 1500 Q64620 0 Serine/threonine-protein phosphatase 6 catalytic subunit (PP6C) (EC 3.1.3.16) (Protein phosphatase V) (PP-V) Rattus norvegicus (Rat) G1/S transition of mitotic cell cycle [GO:0000082]; innate immune response [GO:0045087]; protein dephosphorylation [GO:0006470] GO:0000082; GO:0004722; GO:0005737; GO:0005739; GO:0005829; GO:0006470; GO:0017018; GO:0045087; GO:0046872 21900 XR_006397893.1 265 107 53 151 124 Q9M2U3 6.8e-30 Protein ALP1-like (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) NA GO:0000118; GO:0004518; GO:0046872 21901 XR_006397893.1 265 107 53 151 124 Q9M2U3 6.8e-30 Protein ALP1-like (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) NA GO:0000118; GO:0004518; GO:0046872 21902 XR_006391995.1 15 68 64 8 121 NA NA NA NA NA NA 21903 XR_006392868.1 41 2 25 5 151 NA NA NA NA NA NA 21904 XM_029332007.2 402 152 251 328 444 NA NA NA NA NA NA 21905 XM_029330012.2 1232 728 723 706 651 NA NA NA NA NA NA 21906 XM_044326485.1 15 15 0 70 9 Q5XIX3 5.78e-96 Protein artemis (EC 3.1.-.-) (DNA cross-link repair 1C protein) (SNM1-like protein) Rattus norvegicus (Rat) adaptive immune response [GO:0002250]; B cell differentiation [GO:0030183]; chromosome organization [GO:0051276]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; double-strand break repair via nonhomologous end joining [GO:0006303]; interstrand cross-link repair [GO:0036297]; protection from non-homologous end joining at telomere [GO:0031848]; response to ionizing radiation [GO:0010212]; telomere maintenance [GO:0000723]; V(D)J recombination [GO:0033151] GO:0000014; GO:0000723; GO:0002250; GO:0003684; GO:0005654; GO:0005794; GO:0006302; GO:0006303; GO:0006310; GO:0008409; GO:0010212; GO:0030183; GO:0031848; GO:0033151; GO:0035312; GO:0036297; GO:0051276; GO:0070419 21907 XM_029325386.2 0 49 0 0 87 NA NA NA NA NA NA 21908 XM_029339708.2 714 540 410 332 454 Q13526 1.35e-64 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase Pin1) (PPIase Pin1) (Rotamase Pin1) Homo sapiens (Human) cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of GTPase activity [GO:0043547]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808] GO:0000413; GO:0001666; GO:0001932; GO:0001934; GO:0003755; GO:0003774; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0007049; GO:0007088; GO:0008013; GO:0010468; GO:0016607; GO:0016859; GO:0030182; GO:0030496; GO:0030512; GO:0031434; GO:0031647; GO:0032091; GO:0032092; GO:0032465; GO:0032794; GO:0035307; GO:0036064; GO:0042177; GO:0043547; GO:0045944; GO:0048156; GO:0050808; GO:0050815; GO:0050816; GO:0050821; GO:0051219; GO:0051443; GO:0060393; GO:0070373; GO:0090263; GO:0098978; GO:0099524; GO:1900180; GO:1902430; GO:2000146 21909 XM_044319651.1 0 0 59 17 14 NA NA NA NA NA NA 21910 XR_006393445.1 28 10 6 13 13 NA NA NA NA NA NA 21911 XM_044320069.1 47 34 34 52 63 G3M4F8 6.03e-41 Octopamine receptor beta-2R (CsOA2B2) Chilo suppressalis (Asiatic rice borer moth) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cellular response to amine stimulus [GO:0071418]; octopamine signaling pathway [GO:0071927]; tyramine signaling pathway [GO:0071928] GO:0004989; GO:0005886; GO:0007189; GO:0008226; GO:0016020; GO:0071418; GO:0071927; GO:0071928 21912 XM_044320069.1 47 34 34 52 63 G3M4F8 2.89e-40 Octopamine receptor beta-2R (CsOA2B2) Chilo suppressalis (Asiatic rice borer moth) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cellular response to amine stimulus [GO:0071418]; octopamine signaling pathway [GO:0071927]; tyramine signaling pathway [GO:0071928] GO:0004989; GO:0005886; GO:0007189; GO:0008226; GO:0016020; GO:0071418; GO:0071927; GO:0071928 21913 XM_044320846.1 985 334 355 1418 790 Q5VU97 9.74e-51 VWFA and cache domain-containing protein 1 (Cache domain-containing protein 1) Homo sapiens (Human) NA GO:0005245; GO:0005891 21914 XR_006396505.1 30 26 21 78 33 NA NA NA NA NA NA 21915 XM_044328991.1 87 62 48 113 116 NA NA NA NA NA NA 21916 XM_044313064.1 0 60 45 75 62 O43603 1.67e-21 Galanin receptor type 2 (GAL2-R) (GALR-2) Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell surface receptor signaling pathway [GO:0007166]; feeding behavior [GO:0007631]; galanin-activated signaling pathway [GO:0090663]; inositol phosphate metabolic process [GO:0043647]; learning or memory [GO:0007611]; muscle contraction [GO:0006936]; negative regulation of adenylate cyclase activity [GO:0007194]; neuron projection development [GO:0031175]; neuropeptide signaling pathway [GO:0007218]; phosphatidylinositol metabolic process [GO:0046488]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of large conductance calcium-activated potassium channel activity [GO:1902608]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0004966; GO:0005886; GO:0005929; GO:0006936; GO:0007166; GO:0007188; GO:0007189; GO:0007194; GO:0007200; GO:0007204; GO:0007218; GO:0007611; GO:0007631; GO:0008528; GO:0016020; GO:0017046; GO:0031175; GO:0042923; GO:0043647; GO:0045944; GO:0046488; GO:0090663; GO:1902608 21917 XM_044314057.1 35 20 27 89 49 NA NA NA NA NA NA 21918 XM_029328816.2 34 0 48 41 107 P50430 3.95e-153 Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S) Rattus norvegicus (Rat) anterior head development [GO:0097065]; autophagy [GO:0006914]; central nervous system development [GO:0007417]; colon epithelial cell migration [GO:0061580]; dermatan sulfate catabolic process [GO:0030209]; positive regulation of neuron projection development [GO:0010976]; regulation of epithelial cell migration [GO:0010632]; response to estrogen [GO:0043627]; response to methylmercury [GO:0051597]; response to nutrient [GO:0007584]; response to pH [GO:0009268] GO:0003943; GO:0004065; GO:0005739; GO:0005764; GO:0005791; GO:0005794; GO:0006914; GO:0007417; GO:0007584; GO:0008484; GO:0009268; GO:0009986; GO:0010632; GO:0010976; GO:0030209; GO:0043627; GO:0043890; GO:0046872; GO:0051597; GO:0061580; GO:0097065 21919 XM_029340916.2 129 59 101 42 139 NA NA NA NA NA NA 21920 XM_029339816.2 0 0 39 0 0 Q460N5 2.33e-101 Protein mono-ADP-ribosyltransferase PARP14 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (B aggressive lymphoma protein 2) (Poly [ADP-ribose] polymerase 14) (PARP-14) Homo sapiens (Human) innate immune response [GO:0045087]; negative regulation of gene expression [GO:0010629]; negative regulation of type II interferon-mediated signaling pathway [GO:0060336]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; positive regulation of interleukin-4-mediated signaling pathway [GO:1902216]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein poly-ADP-ribosylation [GO:0070212] GO:0003714; GO:0003950; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0010629; GO:0016020; GO:0016779; GO:0019899; GO:0042531; GO:0042532; GO:0045087; GO:0060336; GO:0070212; GO:0070403; GO:1902216; GO:1990404 21921 XM_029339816.2 0 0 39 0 0 Q460N5 3.56e-31 Protein mono-ADP-ribosyltransferase PARP14 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (B aggressive lymphoma protein 2) (Poly [ADP-ribose] polymerase 14) (PARP-14) Homo sapiens (Human) innate immune response [GO:0045087]; negative regulation of gene expression [GO:0010629]; negative regulation of type II interferon-mediated signaling pathway [GO:0060336]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; positive regulation of interleukin-4-mediated signaling pathway [GO:1902216]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein poly-ADP-ribosylation [GO:0070212] GO:0003714; GO:0003950; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0010629; GO:0016020; GO:0016779; GO:0019899; GO:0042531; GO:0042532; GO:0045087; GO:0060336; GO:0070212; GO:0070403; GO:1902216; GO:1990404 21922 XR_006392072.1 28 17 36 43 117 NA NA NA NA NA NA 21923 XR_006392929.1 41 2 25 5 151 NA NA NA NA NA NA 21924 XM_044316151.1 10 4 0 0 0 NA NA NA NA NA NA 21925 XM_029334655.2 861 562 544 1844 1467 Q08EN7 1.21e-27 Zinc finger CW-type PWWP domain protein 2 homolog Mus musculus (Mouse) NA GO:0005634; GO:0008270; GO:0035064 21926 XM_044317471.1 113 260 13 119 331 Q8BS35 2.17e-82 Alkylglycerol monooxygenase (EC 1.14.16.5) (Transmembrane protein 195) Mus musculus (Mouse) ether lipid metabolic process [GO:0046485]; lipid biosynthetic process [GO:0008610]; membrane lipid metabolic process [GO:0006643] GO:0005506; GO:0005783; GO:0005789; GO:0006643; GO:0008610; GO:0046485; GO:0050479 21927 XM_044317471.1 113 260 13 119 331 Q8BS35 2.17e-82 Alkylglycerol monooxygenase (EC 1.14.16.5) (Transmembrane protein 195) Mus musculus (Mouse) ether lipid metabolic process [GO:0046485]; lipid biosynthetic process [GO:0008610]; membrane lipid metabolic process [GO:0006643] GO:0005506; GO:0005783; GO:0005789; GO:0006643; GO:0008610; GO:0046485; GO:0050479 21928 XM_029338234.2 13030 13342 12069 9072 9035 NA NA NA NA NA NA 21929 XM_044313674.1 682 425 604 179 53 Q96P20 2.96e-44 NACHT, LRR and PYD domains-containing protein 3 (EC 3.6.4.-) (Angiotensin/vasopressin receptor AII/AVP-like) (Caterpiller protein 1.1) (CLR1.1) (Cold-induced autoinflammatory syndrome 1 protein) (Cryopyrin) (PYRIN-containing APAF1-like protein 1) Homo sapiens (Human) apoptotic process [GO:0006915]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to virus [GO:0098586]; defense response [GO:0006952]; detection of biotic stimulus [GO:0009595]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; NLRP3 inflammasome complex assembly [GO:0044546]; osmosensory signaling pathway [GO:0007231]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type 2 immune response [GO:0002830]; protein homooligomerization [GO:0051260]; pyroptosis [GO:0070269]; regulation of inflammatory response [GO:0050727]; signal transduction [GO:0007165] GO:0000139; GO:0002221; GO:0002674; GO:0002830; GO:0005524; GO:0005576; GO:0005634; GO:0005737; GO:0005739; GO:0005783; GO:0005815; GO:0005829; GO:0006915; GO:0006952; GO:0006954; GO:0007165; GO:0007231; GO:0009595; GO:0016020; GO:0016887; GO:0031021; GO:0032088; GO:0032691; GO:0032731; GO:0032753; GO:0035591; GO:0042802; GO:0042834; GO:0043280; GO:0043531; GO:0043565; GO:0044546; GO:0045087; GO:0045630; GO:0045944; GO:0050727; GO:0050728; GO:0050729; GO:0051092; GO:0051260; GO:0070269; GO:0070273; GO:0071222; GO:0072559; GO:0098586; GO:0140297; GO:0140299; GO:1901223; GO:1901981; GO:2000553 21930 XM_044322697.1 526 468 382 357 424 H9XP47 7.43e-41 NA NA NA NA 21931 XM_029344138.2 517 243 226 352 601 Q6NS52 0 Diacylglycerol kinase beta (DAG kinase beta) (EC 2.7.1.107) (Diglyceride kinase beta) (DGK-beta) Mus musculus (Mouse) diacylglycerol metabolic process [GO:0046339]; glycerolipid metabolic process [GO:0046486]; intracellular signal transduction [GO:0035556]; lipid phosphorylation [GO:0046834]; modulation of chemical synaptic transmission [GO:0050804]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidic acid metabolic process [GO:0046473]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; regulation of postsynapse organization [GO:0099175]; response to bacterium [GO:0009617] GO:0004143; GO:0005509; GO:0005524; GO:0005829; GO:0005886; GO:0006654; GO:0007205; GO:0008289; GO:0009617; GO:0016020; GO:0035556; GO:0046339; GO:0046473; GO:0046486; GO:0046834; GO:0050804; GO:0098685; GO:0098978; GO:0099147; GO:0099175 21932 XM_044307868.1 0 147 1308 46 1046 P23468 0 Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48) Homo sapiens (Human) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; neuron differentiation [GO:0030182]; phosphate-containing compound metabolic process [GO:0006796]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse assembly [GO:0051965]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; regulation of immune response [GO:0050776]; regulation of postsynaptic density assembly [GO:0099151]; synaptic membrane adhesion [GO:0099560]; trans-synaptic signaling by trans-synaptic complex [GO:0099545]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185] GO:0004725; GO:0005001; GO:0005102; GO:0005886; GO:0006470; GO:0006796; GO:0007157; GO:0007185; GO:0030182; GO:0042734; GO:0046426; GO:0050775; GO:0050776; GO:0050804; GO:0050839; GO:0051965; GO:0070062; GO:0097105; GO:0098685; GO:0098686; GO:0098978; GO:0099054; GO:0099151; GO:0099545; GO:0099560 21933 XM_044307868.1 0 147 1308 46 1046 P23468 7.31e-73 Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48) Homo sapiens (Human) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; neuron differentiation [GO:0030182]; phosphate-containing compound metabolic process [GO:0006796]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse assembly [GO:0051965]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; regulation of immune response [GO:0050776]; regulation of postsynaptic density assembly [GO:0099151]; synaptic membrane adhesion [GO:0099560]; trans-synaptic signaling by trans-synaptic complex [GO:0099545]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185] GO:0004725; GO:0005001; GO:0005102; GO:0005886; GO:0006470; GO:0006796; GO:0007157; GO:0007185; GO:0030182; GO:0042734; GO:0046426; GO:0050775; GO:0050776; GO:0050804; GO:0050839; GO:0051965; GO:0070062; GO:0097105; GO:0098685; GO:0098686; GO:0098978; GO:0099054; GO:0099151; GO:0099545; GO:0099560 21934 XM_044307868.1 0 147 1308 46 1046 P23468 3.52e-62 Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48) Homo sapiens (Human) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; neuron differentiation [GO:0030182]; phosphate-containing compound metabolic process [GO:0006796]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse assembly [GO:0051965]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; regulation of immune response [GO:0050776]; regulation of postsynaptic density assembly [GO:0099151]; synaptic membrane adhesion [GO:0099560]; trans-synaptic signaling by trans-synaptic complex [GO:0099545]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185] GO:0004725; GO:0005001; GO:0005102; GO:0005886; GO:0006470; GO:0006796; GO:0007157; GO:0007185; GO:0030182; GO:0042734; GO:0046426; GO:0050775; GO:0050776; GO:0050804; GO:0050839; GO:0051965; GO:0070062; GO:0097105; GO:0098685; GO:0098686; GO:0098978; GO:0099054; GO:0099151; GO:0099545; GO:0099560 21935 XM_044307868.1 0 147 1308 46 1046 P23468 1.12e-61 Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48) Homo sapiens (Human) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; neuron differentiation [GO:0030182]; phosphate-containing compound metabolic process [GO:0006796]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse assembly [GO:0051965]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; regulation of immune response [GO:0050776]; regulation of postsynaptic density assembly [GO:0099151]; synaptic membrane adhesion [GO:0099560]; trans-synaptic signaling by trans-synaptic complex [GO:0099545]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185] GO:0004725; GO:0005001; GO:0005102; GO:0005886; GO:0006470; GO:0006796; GO:0007157; GO:0007185; GO:0030182; GO:0042734; GO:0046426; GO:0050775; GO:0050776; GO:0050804; GO:0050839; GO:0051965; GO:0070062; GO:0097105; GO:0098685; GO:0098686; GO:0098978; GO:0099054; GO:0099151; GO:0099545; GO:0099560 21936 XM_044307868.1 0 147 1308 46 1046 P23468 5.27e-45 Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48) Homo sapiens (Human) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; neuron differentiation [GO:0030182]; phosphate-containing compound metabolic process [GO:0006796]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse assembly [GO:0051965]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; regulation of immune response [GO:0050776]; regulation of postsynaptic density assembly [GO:0099151]; synaptic membrane adhesion [GO:0099560]; trans-synaptic signaling by trans-synaptic complex [GO:0099545]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185] GO:0004725; GO:0005001; GO:0005102; GO:0005886; GO:0006470; GO:0006796; GO:0007157; GO:0007185; GO:0030182; GO:0042734; GO:0046426; GO:0050775; GO:0050776; GO:0050804; GO:0050839; GO:0051965; GO:0070062; GO:0097105; GO:0098685; GO:0098686; GO:0098978; GO:0099054; GO:0099151; GO:0099545; GO:0099560 21937 XR_006395516.1 7 0 1 0 0 NA NA NA NA NA NA 21938 XM_044310825.1 18 110 8 3 21 Q91ZV2 3e-24 Discoidin, CUB and LCCL domain-containing protein 2 (Endothelial and smooth muscle cell-derived neuropilin-like protein) Rattus norvegicus (Rat) negative regulation of cell growth [GO:0030308]; wound healing [GO:0042060] GO:0005886; GO:0009986; GO:0030308; GO:0038023; GO:0042060 21939 XR_006395914.1 88 11 21 47 27 Q7Z020 4.68e-75 Transient receptor potential cation channel subfamily A member 1 (dTRPA1) (Ankyrin-like with transmembrane domains protein 1) (dANKTM1) Drosophila melanogaster (Fruit fly) calcium ion transport [GO:0006816]; cation transport [GO:0006812]; cellular response to heat [GO:0034605]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; detection of temperature stimulus involved in thermoception [GO:0050960]; mechanosensory behavior [GO:0007638]; negative phototaxis [GO:0046957]; neuronal signal transduction [GO:0023041]; phototransduction [GO:0007602]; positive regulation of calcium-mediated signaling [GO:0050850]; response to heat [GO:0009408]; response to light stimulus [GO:0009416]; temperature compensation of the circadian clock [GO:0010378]; thermosensory behavior [GO:0040040]; thermotaxis [GO:0043052] GO:0001580; GO:0005261; GO:0005262; GO:0005886; GO:0006812; GO:0006816; GO:0007602; GO:0007638; GO:0009408; GO:0009416; GO:0010378; GO:0015276; GO:0016020; GO:0023041; GO:0034605; GO:0034703; GO:0040040; GO:0043052; GO:0046957; GO:0050850; GO:0050960; GO:0050965; GO:0050968; GO:0097604 21940 XR_006395914.1 88 11 21 47 27 Q7Z020 4.68e-75 Transient receptor potential cation channel subfamily A member 1 (dTRPA1) (Ankyrin-like with transmembrane domains protein 1) (dANKTM1) Drosophila melanogaster (Fruit fly) calcium ion transport [GO:0006816]; cation transport [GO:0006812]; cellular response to heat [GO:0034605]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; detection of temperature stimulus involved in thermoception [GO:0050960]; mechanosensory behavior [GO:0007638]; negative phototaxis [GO:0046957]; neuronal signal transduction [GO:0023041]; phototransduction [GO:0007602]; positive regulation of calcium-mediated signaling [GO:0050850]; response to heat [GO:0009408]; response to light stimulus [GO:0009416]; temperature compensation of the circadian clock [GO:0010378]; thermosensory behavior [GO:0040040]; thermotaxis [GO:0043052] GO:0001580; GO:0005261; GO:0005262; GO:0005886; GO:0006812; GO:0006816; GO:0007602; GO:0007638; GO:0009408; GO:0009416; GO:0010378; GO:0015276; GO:0016020; GO:0023041; GO:0034605; GO:0034703; GO:0040040; GO:0043052; GO:0046957; GO:0050850; GO:0050960; GO:0050965; GO:0050968; GO:0097604 21941 XR_006395914.1 88 11 21 47 27 Q7Z020 5.37e-24 Transient receptor potential cation channel subfamily A member 1 (dTRPA1) (Ankyrin-like with transmembrane domains protein 1) (dANKTM1) Drosophila melanogaster (Fruit fly) calcium ion transport [GO:0006816]; cation transport [GO:0006812]; cellular response to heat [GO:0034605]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; detection of temperature stimulus involved in thermoception [GO:0050960]; mechanosensory behavior [GO:0007638]; negative phototaxis [GO:0046957]; neuronal signal transduction [GO:0023041]; phototransduction [GO:0007602]; positive regulation of calcium-mediated signaling [GO:0050850]; response to heat [GO:0009408]; response to light stimulus [GO:0009416]; temperature compensation of the circadian clock [GO:0010378]; thermosensory behavior [GO:0040040]; thermotaxis [GO:0043052] GO:0001580; GO:0005261; GO:0005262; GO:0005886; GO:0006812; GO:0006816; GO:0007602; GO:0007638; GO:0009408; GO:0009416; GO:0010378; GO:0015276; GO:0016020; GO:0023041; GO:0034605; GO:0034703; GO:0040040; GO:0043052; GO:0046957; GO:0050850; GO:0050960; GO:0050965; GO:0050968; GO:0097604 21942 XM_044310310.1 19 5 12 9 0 NA NA NA NA NA NA 21943 XM_044318523.1 30 11 5 113 38 P0CI65 3.2e-40 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 21944 XM_044318523.1 30 11 5 113 38 P0CI65 2.48e-36 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 21945 XM_044310463.1 24 31 50 0 0 NA NA NA NA NA NA 21946 XM_029330414.2 0 13 22 0 137 Q9EQD2 1.47e-37 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 21947 XM_029323591.2 433 217 90 175 170 P24507 3.79e-36 Synaptotagmin-C (Synaptic vesicle protein O-p65-C) Diplobatis ommata (Ocellated electric ray) (Discopyge ommata) NA GO:0030672; GO:0046872 21948 XR_003825142.2 14 6 7 10 5 NA NA NA NA NA NA 21949 XM_029333699.2 453 17 262 0 138 Q9H0Y0 4.26e-25 Ubiquitin-like-conjugating enzyme ATG10 (EC 2.3.2.-) (Autophagy-related protein 10) (APG10-like) Homo sapiens (Human) autophagy [GO:0006914]; ER overload response [GO:0006983]; macroautophagy [GO:0016236]; positive regulation of protein modification process [GO:0031401]; protein lipidation [GO:0006497]; protein modification by small protein conjugation [GO:0032446]; protein transport [GO:0015031] GO:0005829; GO:0006497; GO:0006914; GO:0006983; GO:0015031; GO:0016236; GO:0019777; GO:0031401; GO:0032446 21950 XM_029333699.2 453 17 262 0 138 Q9H0Y0 4.26e-25 Ubiquitin-like-conjugating enzyme ATG10 (EC 2.3.2.-) (Autophagy-related protein 10) (APG10-like) Homo sapiens (Human) autophagy [GO:0006914]; ER overload response [GO:0006983]; macroautophagy [GO:0016236]; positive regulation of protein modification process [GO:0031401]; protein lipidation [GO:0006497]; protein modification by small protein conjugation [GO:0032446]; protein transport [GO:0015031] GO:0005829; GO:0006497; GO:0006914; GO:0006983; GO:0015031; GO:0016236; GO:0019777; GO:0031401; GO:0032446 21951 XM_044317176.1 0 97 88 0 0 NA NA NA NA NA NA 21952 XR_006396444.1 28 0 30 30 114 NA NA NA NA NA NA 21953 XM_044318558.1 84 19 103 128 70 Q68F72 9.07e-86 Solute carrier family 15 member 4 Xenopus laevis (African clawed frog) dipeptide import across plasma membrane [GO:0140206]; innate immune response [GO:0045087]; mast cell homeostasis [GO:0033023]; peptidoglycan transport [GO:0015835]; positive regulation of innate immune response [GO:0045089]; positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [GO:0070430]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of toll-like receptor 7 signaling pathway [GO:0034157]; positive regulation of toll-like receptor 8 signaling pathway [GO:0034161]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; protein transport [GO:0015031]; regulation of isotype switching to IgG isotypes [GO:0048302]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424] GO:0005290; GO:0005765; GO:0015031; GO:0015333; GO:0015647; GO:0015835; GO:0031901; GO:0033023; GO:0034157; GO:0034161; GO:0034165; GO:0036020; GO:0045087; GO:0045089; GO:0048302; GO:0070424; GO:0070430; GO:0070434; GO:0071916; GO:0140206 21954 XM_029342106.2 12100 12441 13031 11940 12326 NA NA NA NA NA NA 21955 XM_029349330.2 26 33 5 0 27 Q6DFC2 2.53e-170 Coiled-coil domain-containing protein 77 Xenopus laevis (African clawed frog) NA NA 21956 XR_006395514.1 0 0 13 1 0 NA NA NA NA NA NA 21957 XM_029335851.2 107 0 0 0 0 Q75V66 0 Anoctamin-5 (Gnathodiaphyseal dysplasia 1 protein) (Transmembrane protein 16E) Homo sapiens (Human) chloride transmembrane transport [GO:1902476]; chloride transport [GO:0006821]; ion transmembrane transport [GO:0034220]; transmembrane transport [GO:0055085] GO:0005229; GO:0005254; GO:0005789; GO:0005886; GO:0006821; GO:0031982; GO:0034220; GO:0046983; GO:0055085; GO:1902476 21958 XR_006391875.1 1 148 0 0 0 NA NA NA NA NA NA 21959 XR_006397108.1 0 11 0 0 39 NA NA NA NA NA NA 21960 XM_044318700.1 23 5 13 11 25 NA NA NA NA NA NA 21961 XM_029333018.2 0 0 0 15 37 Q9WVD0 1.17e-21 Neuropeptide Y receptor type 1 (NPY1-R) Cavia porcellus (Guinea pig) NA GO:0004983; GO:0005886 21962 XR_006397047.1 0 0 0 0 11 NA NA NA NA NA NA 21963 XM_029356956.2 223 331 341 460 273 NA NA NA NA NA NA 21964 XM_029355244.2 237 4 133 32 153 NA NA NA NA NA NA 21965 XM_044314932.1 60 8 1 89 23 Q96AY4 9.77e-56 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21966 XM_044314932.1 60 8 1 89 23 Q96AY4 2.62e-54 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21967 XM_044314932.1 60 8 1 89 23 Q96AY4 3.83e-50 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21968 XM_044314932.1 60 8 1 89 23 Q96AY4 9.41e-50 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21969 XM_044314932.1 60 8 1 89 23 Q96AY4 2.08e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21970 XM_044314932.1 60 8 1 89 23 Q96AY4 4.71e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21971 XM_044314932.1 60 8 1 89 23 Q96AY4 1.29e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21972 XM_044314932.1 60 8 1 89 23 Q96AY4 3.07e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21973 XM_044314932.1 60 8 1 89 23 Q96AY4 1.43e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21974 XM_044314932.1 60 8 1 89 23 Q96AY4 8.95e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21975 XM_029329334.2 70 44 49 13 13 NA NA NA NA NA NA 21976 XM_044310732.1 17 0 0 15 17 B3EWZ5 1.74e-83 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 21977 XM_044310732.1 17 0 0 15 17 B3EWZ5 7.8e-74 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 21978 XM_044310732.1 17 0 0 15 17 B3EWZ5 2.01e-72 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 21979 XM_044310732.1 17 0 0 15 17 B3EWZ5 2.92e-69 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 21980 XM_044310732.1 17 0 0 15 17 B3EWZ5 3.16e-68 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 21981 XM_044310732.1 17 0 0 15 17 B3EWZ5 5.33e-68 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 21982 XM_044310732.1 17 0 0 15 17 B3EWZ5 2.14e-66 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 21983 XM_044310732.1 17 0 0 15 17 B3EWZ5 3.8e-66 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 21984 XM_044310732.1 17 0 0 15 17 B3EWZ5 4.38e-63 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 21985 XM_044310732.1 17 0 0 15 17 B3EWZ5 1.36e-61 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 21986 XM_044310732.1 17 0 0 15 17 B3EWZ5 1.37e-57 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 21987 XM_044310732.1 17 0 0 15 17 B3EWZ5 5.66e-52 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 21988 XM_044310732.1 17 0 0 15 17 B3EWZ5 2.1e-51 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 21989 XM_044310732.1 17 0 0 15 17 B3EWZ5 1.73e-50 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 21990 XM_044310732.1 17 0 0 15 17 B3EWZ5 2.93e-45 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 21991 XM_044310732.1 17 0 0 15 17 B3EWZ5 7.42e-41 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 21992 XM_044310732.1 17 0 0 15 17 B3EWZ5 7.13e-36 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 21993 XM_044310732.1 17 0 0 15 17 B3EWZ5 9.55e-36 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 21994 XM_044310732.1 17 0 0 15 17 B3EWZ5 2.58e-34 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 21995 XM_044310732.1 17 0 0 15 17 B3EWZ5 5.52e-34 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 21996 XM_044310732.1 17 0 0 15 17 B3EWZ5 4.52e-31 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 21997 XM_044310732.1 17 0 0 15 17 B3EWZ5 8.51e-31 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 21998 XM_044326008.1 398 390 329 320 498 NA NA NA NA NA NA 21999 XM_029349855.2 493 383 236 269 229 Q6TDP4 0 Kelch-like protein 17 (Actinfilin) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; protein ubiquitination [GO:0016567]; regulation protein catabolic process at postsynapse [GO:0140252] GO:0005615; GO:0007420; GO:0014069; GO:0015629; GO:0016567; GO:0030036; GO:0031208; GO:0032839; GO:0043025; GO:0051015; GO:0060090; GO:0098978; GO:0140252 22000 XM_044311050.1 118 9 1 286 64 NA NA NA NA NA NA 22001 XM_044327768.1 0 11 0 0 0 NA NA NA NA NA NA 22002 XM_044320495.1 0 30 5 5 0 NA NA NA NA NA NA 22003 XM_044307459.1 1132 679 612 1025 1674 NA NA NA NA NA NA 22004 XM_044321753.1 0 21 4 11 3 Q2VPA6 0 Helicase POLQ-like (EC 3.6.4.12) (Mus308-like helicase) (POLQ-like helicase) Mus musculus (Mouse) DNA double-strand break processing involved in repair via single-strand annealing [GO:0010792]; DNA metabolic process [GO:0006259]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via synthesis-dependent strand annealing [GO:0045003]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; rRNA processing [GO:0006364] GO:0000724; GO:0003677; GO:0005524; GO:0005634; GO:0006259; GO:0006364; GO:0010792; GO:0016887; GO:0017116; GO:0017117; GO:0045003; GO:0090734; GO:0097681; GO:1905168; GO:1990518 22005 XR_006394410.1 19 31 8 16 17 NA NA NA NA NA NA 22006 XM_029334703.2 2091 2180 1838 2250 4027 P02752 2.58e-42 Riboflavin-binding protein (RBP) [Cleaved into: Riboflavin-binding protein, plasma form; Riboflavin-binding protein, yolk major form; Riboflavin-binding protein, yolk minor form] Gallus gallus (Chicken) negative regulation of sensory perception of bitter taste [GO:1904661]; negative regulation of sensory perception of sweet taste [GO:1904657]; riboflavin transport [GO:0032218] GO:0009897; GO:0032217; GO:0032218; GO:0038023; GO:1902444; GO:1904657; GO:1904661 22007 XM_029333633.2 528 379 0 583 247 P53349 2.43e-112 Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1) Mus musculus (Mouse) apoptotic mitochondrial changes [GO:0008637]; camera-type eye development [GO:0043010]; epithelial cell morphogenesis [GO:0003382]; eyelid development in camera-type eye [GO:0061029]; JNK cascade [GO:0007254]; MAPK cascade [GO:0000165]; morphogenesis of an epithelial sheet [GO:0002011]; negative regulation of actin filament bundle assembly [GO:0032232]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of viral transcription [GO:0050434]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein polyubiquitination [GO:0000209]; regulation of cell migration [GO:0030334]; response to osmotic stress [GO:0006970]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ubiquitin-dependent protein catabolic process [GO:0006511]; wound healing [GO:0042060] GO:0000165; GO:0000209; GO:0002011; GO:0003382; GO:0004672; GO:0004674; GO:0004706; GO:0004708; GO:0004709; GO:0004842; GO:0005524; GO:0005737; GO:0005829; GO:0005856; GO:0006468; GO:0006511; GO:0006970; GO:0007179; GO:0007254; GO:0008092; GO:0008270; GO:0008432; GO:0008637; GO:0016020; GO:0018105; GO:0019901; GO:0030054; GO:0030334; GO:0030838; GO:0031434; GO:0031941; GO:0032232; GO:0042060; GO:0043010; GO:0043065; GO:0043406; GO:0043410; GO:0043507; GO:0044877; GO:0045893; GO:0045944; GO:0046330; GO:0046625; GO:0046777; GO:0050434; GO:0051019; GO:0061029; GO:0090263; GO:0106310 22008 XM_029333633.2 528 379 0 583 247 P53349 2.77e-112 Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1) Mus musculus (Mouse) apoptotic mitochondrial changes [GO:0008637]; camera-type eye development [GO:0043010]; epithelial cell morphogenesis [GO:0003382]; eyelid development in camera-type eye [GO:0061029]; JNK cascade [GO:0007254]; MAPK cascade [GO:0000165]; morphogenesis of an epithelial sheet [GO:0002011]; negative regulation of actin filament bundle assembly [GO:0032232]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of viral transcription [GO:0050434]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein polyubiquitination [GO:0000209]; regulation of cell migration [GO:0030334]; response to osmotic stress [GO:0006970]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ubiquitin-dependent protein catabolic process [GO:0006511]; wound healing [GO:0042060] GO:0000165; GO:0000209; GO:0002011; GO:0003382; GO:0004672; GO:0004674; GO:0004706; GO:0004708; GO:0004709; GO:0004842; GO:0005524; GO:0005737; GO:0005829; GO:0005856; GO:0006468; GO:0006511; GO:0006970; GO:0007179; GO:0007254; GO:0008092; GO:0008270; GO:0008432; GO:0008637; GO:0016020; GO:0018105; GO:0019901; GO:0030054; GO:0030334; GO:0030838; GO:0031434; GO:0031941; GO:0032232; GO:0042060; GO:0043010; GO:0043065; GO:0043406; GO:0043410; GO:0043507; GO:0044877; GO:0045893; GO:0045944; GO:0046330; GO:0046625; GO:0046777; GO:0050434; GO:0051019; GO:0061029; GO:0090263; GO:0106310 22009 XM_044324355.1 300 248 344 697 779 Q7Z407 2.07e-92 CUB and sushi domain-containing protein 3 (CUB and sushi multiple domains protein 3) Homo sapiens (Human) negative regulation of complement activation, classical pathway [GO:0045959]; regulation of dendrite development [GO:0050773] GO:0005615; GO:0005886; GO:0045959; GO:0050773 22010 XM_044324355.1 300 248 344 697 779 Q7Z407 5.95e-70 CUB and sushi domain-containing protein 3 (CUB and sushi multiple domains protein 3) Homo sapiens (Human) negative regulation of complement activation, classical pathway [GO:0045959]; regulation of dendrite development [GO:0050773] GO:0005615; GO:0005886; GO:0045959; GO:0050773 22011 XM_044324355.1 300 248 344 697 779 Q7Z407 6.38e-55 CUB and sushi domain-containing protein 3 (CUB and sushi multiple domains protein 3) Homo sapiens (Human) negative regulation of complement activation, classical pathway [GO:0045959]; regulation of dendrite development [GO:0050773] GO:0005615; GO:0005886; GO:0045959; GO:0050773 22012 XM_044312233.1 11 24 13 211 18 NA NA NA NA NA NA 22013 XM_029330201.2 2202 3123 1391 2066 1382 NA NA NA NA NA NA 22014 XM_044310103.1 0 0 5 0 53 NA NA NA NA NA NA 22015 XM_029338712.2 32 0 21 38 0 NA NA NA NA NA NA 22016 XM_044327051.1 89 18 34 83 66 Q8NDA2 2.42e-28 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 22017 XM_044321456.1 67 66 40 223 637 Q14192 5.11e-64 Four and a half LIM domains protein 2 (FHL-2) (LIM domain protein DRAL) (Skeletal muscle LIM-protein 3) (SLIM-3) Homo sapiens (Human) atrial cardiac muscle cell development [GO:0055014]; heart trabecula formation [GO:0060347]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of transcription by RNA polymerase II [GO:0000122]; osteoblast differentiation [GO:0001649]; response to hormone [GO:0009725]; ventricular cardiac muscle cell development [GO:0055015] GO:0000122; GO:0001649; GO:0003712; GO:0003714; GO:0005634; GO:0005654; GO:0005925; GO:0008134; GO:0009725; GO:0030018; GO:0042802; GO:0043066; GO:0043425; GO:0046872; GO:0055014; GO:0055015; GO:0060347; GO:0070885 22018 XM_044321456.1 67 66 40 223 637 Q14192 3.42e-34 Four and a half LIM domains protein 2 (FHL-2) (LIM domain protein DRAL) (Skeletal muscle LIM-protein 3) (SLIM-3) Homo sapiens (Human) atrial cardiac muscle cell development [GO:0055014]; heart trabecula formation [GO:0060347]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of transcription by RNA polymerase II [GO:0000122]; osteoblast differentiation [GO:0001649]; response to hormone [GO:0009725]; ventricular cardiac muscle cell development [GO:0055015] GO:0000122; GO:0001649; GO:0003712; GO:0003714; GO:0005634; GO:0005654; GO:0005925; GO:0008134; GO:0009725; GO:0030018; GO:0042802; GO:0043066; GO:0043425; GO:0046872; GO:0055014; GO:0055015; GO:0060347; GO:0070885 22019 XM_044321456.1 67 66 40 223 637 Q14192 1.01e-24 Four and a half LIM domains protein 2 (FHL-2) (LIM domain protein DRAL) (Skeletal muscle LIM-protein 3) (SLIM-3) Homo sapiens (Human) atrial cardiac muscle cell development [GO:0055014]; heart trabecula formation [GO:0060347]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of transcription by RNA polymerase II [GO:0000122]; osteoblast differentiation [GO:0001649]; response to hormone [GO:0009725]; ventricular cardiac muscle cell development [GO:0055015] GO:0000122; GO:0001649; GO:0003712; GO:0003714; GO:0005634; GO:0005654; GO:0005925; GO:0008134; GO:0009725; GO:0030018; GO:0042802; GO:0043066; GO:0043425; GO:0046872; GO:0055014; GO:0055015; GO:0060347; GO:0070885 22020 XM_044321456.1 67 66 40 223 637 Q14192 1.07e-23 Four and a half LIM domains protein 2 (FHL-2) (LIM domain protein DRAL) (Skeletal muscle LIM-protein 3) (SLIM-3) Homo sapiens (Human) atrial cardiac muscle cell development [GO:0055014]; heart trabecula formation [GO:0060347]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of transcription by RNA polymerase II [GO:0000122]; osteoblast differentiation [GO:0001649]; response to hormone [GO:0009725]; ventricular cardiac muscle cell development [GO:0055015] GO:0000122; GO:0001649; GO:0003712; GO:0003714; GO:0005634; GO:0005654; GO:0005925; GO:0008134; GO:0009725; GO:0030018; GO:0042802; GO:0043066; GO:0043425; GO:0046872; GO:0055014; GO:0055015; GO:0060347; GO:0070885 22021 XM_029332024.2 1174 512 543 806 832 P29074 0 Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (MEG) (PTPase-MEG1) Homo sapiens (Human) peptidyl-tyrosine phosphorylation [GO:0018108]; protein dephosphorylation [GO:0006470] GO:0004725; GO:0004726; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0006470; GO:0008092; GO:0009898; GO:0018108; GO:0035254 22022 XM_029335775.2 449 569 284 457 569 P45954 1.07e-178 Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial (SBCAD) (EC 1.3.8.5) (2-methyl branched chain acyl-CoA dehydrogenase) (2-MEBCAD) (2-methylbutyryl-coenzyme A dehydrogenase) (2-methylbutyryl-CoA dehydrogenase) Homo sapiens (Human) fatty acid metabolic process [GO:0006631]; isoleucine catabolic process [GO:0006550] GO:0003853; GO:0003995; GO:0005739; GO:0005759; GO:0006550; GO:0006631; GO:0016937; GO:0042802; GO:0050660; GO:0102035 22023 XM_044310441.1 1388 721 1454 1744 2619 O46385 0 Supervillin (Archvillin) (p205/p250) Bos taurus (Bovine) actin filament severing [GO:0051014]; actin polymerization or depolymerization [GO:0008154]; barbed-end actin filament capping [GO:0051016]; positive regulation of cytokinesis [GO:0032467] GO:0002102; GO:0005546; GO:0005737; GO:0008154; GO:0015629; GO:0030496; GO:0032154; GO:0032467; GO:0036449; GO:0042995; GO:0051014; GO:0051015; GO:0051016; GO:0060090; GO:0070161 22024 XM_029356983.2 1759 1005 1039 1474 1472 A0A1L8F5J9 0 Glutamate receptor ionotropic, NMDA 1 (GluN1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1) Xenopus laevis (African clawed frog) response to zinc ion [GO:0010043] GO:0004972; GO:0005886; GO:0010043; GO:0017146; GO:0045211; GO:0046872 22025 XM_029334985.2 668 264 316 470 527 Q9GZT4 4.46e-105 Serine racemase (EC 5.1.1.18) (D-serine ammonia-lyase) (D-serine dehydratase) (EC 4.3.1.18) (L-serine ammonia-lyase) (L-serine dehydratase) (EC 4.3.1.17) Homo sapiens (Human) aging [GO:0007568]; brain development [GO:0007420]; D-serine biosynthetic process [GO:0070179]; D-serine metabolic process [GO:0070178]; L-serine metabolic process [GO:0006563]; pyruvate biosynthetic process [GO:0042866]; response to lipopolysaccharide [GO:0032496]; response to morphine [GO:0043278]; response to xenobiotic stimulus [GO:0009410]; serine family amino acid metabolic process [GO:0009069] GO:0000287; GO:0003941; GO:0005509; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006563; GO:0007420; GO:0007568; GO:0008721; GO:0009069; GO:0009410; GO:0016594; GO:0018114; GO:0030165; GO:0030170; GO:0030378; GO:0032496; GO:0042802; GO:0042803; GO:0042866; GO:0043025; GO:0043278; GO:0045177; GO:0070178; GO:0070179 22026 XM_029355509.2 526 508 251 206 428 Q9CQM0 4.98e-41 Nicolin-1 (Tubulin polyglutamylase complex subunit 5) (PGs5) (p24) Mus musculus (Mouse) NA GO:0005654; GO:0005829; GO:0005874 22027 XM_029351662.2 719 99 98 266 378 Q567Y6 2.63e-62 Intraflagellar transport protein 22 homolog (Rab-like protein 5) Danio rerio (Zebrafish) (Brachydanio rerio) intracellular protein transport [GO:0006886] GO:0003924; GO:0005525; GO:0006886; GO:0012505; GO:0030992 22028 XM_044324827.1 34 2 19 2 374 P84239 7.58e-94 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 22029 XM_029346259.2 0 13 0 222 0 P61593 3.52e-45 Microcephalin Pan troglodytes (Chimpanzee) cerebral cortex development [GO:0021987]; mitotic cell cycle [GO:0000278] GO:0000278; GO:0005737; GO:0005815; GO:0021987 22030 XM_044309771.1 99 31 3 9 20 NA NA NA NA NA NA 22031 XM_029336452.2 926 396 421 884 750 O70496 0 H(+)/Cl(-) exchange transporter 7 (Chloride channel 7 alpha subunit) (Chloride channel protein 7) (ClC-7) Mus musculus (Mouse) response to pH [GO:0009268]; transepithelial chloride transport [GO:0030321] GO:0005247; GO:0005524; GO:0005765; GO:0009268; GO:0015108; GO:0015297; GO:0030321; GO:0031410; GO:0034707; GO:0043231 22032 XM_029353912.2 119 56 67 149 117 P0DJG4 1.57e-28 Testicular haploid expressed gene protein-like (Theg spermatid-like protein) Homo sapiens (Human) NA NA 22033 XM_044319182.1 1301 1462 872 2280 1706 Q91YN5 2.17e-168 UDP-N-acetylhexosamine pyrophosphorylase [Includes: UDP-N-acetylgalactosamine pyrophosphorylase (EC 2.7.7.83); UDP-N-acetylglucosamine pyrophosphorylase (EC 2.7.7.23)] Mus musculus (Mouse) UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047] GO:0003977; GO:0005654; GO:0005829; GO:0005886; GO:0006047; GO:0006048; GO:0030246; GO:0042802; GO:0052630 22034 XM_044313936.1 46 602 53 4 34 NA NA NA NA NA NA 22035 XR_003824816.2 18 11 137 28 16 NA NA NA NA NA NA 22036 XM_044329278.1 0 0 3 38 21 NA NA NA NA NA NA 22037 XR_006397429.1 13 15 47 46 69 NA NA NA NA NA NA 22038 XM_044313469.1 27 1 45 5 3 NA NA NA NA NA NA 22039 XM_044321560.1 422 320 184 146 68 Q2KIP7 7.59e-69 Mitotic spindle assembly checkpoint protein MAD2B (Mitotic arrest deficient 2-like protein 2) (MAD2-like protein 2) Bos taurus (Bovine) cell cycle [GO:0007049]; cell division [GO:0051301]; DNA damage response, signal transduction resulting in transcription [GO:0042772]; double-strand break repair [GO:0006302]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of ubiquitin protein ligase activity [GO:1904667]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; regulation of cell growth [GO:0001558] GO:0001558; GO:0005634; GO:0005737; GO:0005819; GO:0006302; GO:0007049; GO:0008432; GO:0016035; GO:0033138; GO:0042177; GO:0042772; GO:0045893; GO:0051301; GO:1904667 22040 XM_044308277.1 50 16 45 64 35 E7FAM5 9.14e-59 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 22041 XR_006393441.1 0 18 0 0 0 Q9HAV4 3.26e-35 Exportin-5 (Exp5) (Ran-binding protein 21) Homo sapiens (Human) miRNA metabolic process [GO:0010586]; positive regulation of post-transcriptional gene silencing by RNA [GO:1900370]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; RNA export from nucleus [GO:0006405] GO:0000049; GO:0003723; GO:0003729; GO:0005049; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006405; GO:0006611; GO:0010586; GO:0016442; GO:0031267; GO:0035281; GO:0042565; GO:0070883; GO:1900370; GO:1905172 22042 XM_044306879.1 175 112 160 251 135 P98192 9.16e-112 Dihydroxyacetone phosphate acyltransferase (DAP-AT) (DHAP-AT) (EC 2.3.1.42) (Acyl-CoA:dihydroxyacetonephosphateacyltransferase) (Glycerone-phosphate O-acyltransferase) Mus musculus (Mouse) cerebellum morphogenesis [GO:0021587]; ether lipid biosynthetic process [GO:0008611]; fatty acid metabolic process [GO:0006631]; glycerophospholipid metabolic process [GO:0006650]; membrane organization [GO:0061024]; myelination [GO:0042552]; paranodal junction assembly [GO:0030913]; phospholipid biosynthetic process [GO:0008654]; response to fatty acid [GO:0070542]; response to nutrient [GO:0007584]; response to starvation [GO:0042594]; response to xenobiotic stimulus [GO:0009410]; synapse assembly [GO:0007416] GO:0003824; GO:0005739; GO:0005777; GO:0005778; GO:0005782; GO:0006631; GO:0006650; GO:0007416; GO:0007584; GO:0008611; GO:0008654; GO:0009410; GO:0016287; GO:0021587; GO:0030913; GO:0031966; GO:0042552; GO:0042594; GO:0061024; GO:0070542 22043 XM_029353550.2 47 48 5 40 44 NA NA NA NA NA NA 22044 XM_044308862.1 447 0 45 0 0 NA NA NA NA NA NA 22045 XM_044323900.1 500 190 304 257 1191 NA NA NA NA NA NA 22046 XM_044316146.1 8 0 0 0 0 NA NA NA NA NA NA 22047 XM_029351166.2 11 30 0 23 21 P15043 9.93e-23 ATP-dependent DNA helicase RecQ (EC 3.6.4.12) Escherichia coli (strain K12) cellular response to DNA damage stimulus [GO:0006974]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; SOS response [GO:0009432] GO:0003677; GO:0003678; GO:0005524; GO:0005694; GO:0005737; GO:0006260; GO:0006281; GO:0006310; GO:0006974; GO:0008094; GO:0008270; GO:0009378; GO:0009432; GO:0016887; GO:0017116; GO:0017117; GO:0030894; GO:0032508; GO:0043138; GO:0043590; GO:0046914 22048 XM_044319191.1 809 238 226 595 637 Q460N5 2.53e-152 Protein mono-ADP-ribosyltransferase PARP14 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (B aggressive lymphoma protein 2) (Poly [ADP-ribose] polymerase 14) (PARP-14) Homo sapiens (Human) innate immune response [GO:0045087]; negative regulation of gene expression [GO:0010629]; negative regulation of type II interferon-mediated signaling pathway [GO:0060336]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; positive regulation of interleukin-4-mediated signaling pathway [GO:1902216]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein poly-ADP-ribosylation [GO:0070212] GO:0003714; GO:0003950; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0010629; GO:0016020; GO:0016779; GO:0019899; GO:0042531; GO:0042532; GO:0045087; GO:0060336; GO:0070212; GO:0070403; GO:1902216; GO:1990404 22049 XM_044329226.1 46 50 49 85 124 Q29RY4 1.47e-75 Zinc phosphodiesterase ELAC protein 1 (EC 3.1.26.11) (ElaC homolog protein 1) (Ribonuclease Z 1) (RNase Z 1) (tRNA 3 endonuclease 1) (tRNase Z 1) Bos taurus (Bovine) tRNA 3'-trailer cleavage [GO:0042779] GO:0005634; GO:0005654; GO:0005829; GO:0042779; GO:0042781; GO:0046872 22050 XM_029336461.2 2899 3428 1856 1812 1417 Q7YR75 1.37e-25 39S ribosomal protein L12, mitochondrial (L12mt) (MRP-L12) Bos taurus (Bovine) mitochondrial transcription [GO:0006390]; positive regulation of DNA-templated transcription [GO:0045893]; translation [GO:0006412] GO:0003729; GO:0003735; GO:0005743; GO:0005762; GO:0006390; GO:0006412; GO:0045893 22051 XM_044312048.1 76 16 22 112 33 NA NA NA NA NA NA 22052 XM_044321499.1 19 14 0 48 78 NA NA NA NA NA NA 22053 XR_003824161.2 9 0 0 20 22 NA NA NA NA NA NA 22054 XM_029328453.2 812 243 306 685 1094 Q86UT8 3.26e-40 Centrosomal AT-AC splicing factor (Coiled-coil domain-containing protein 84) Homo sapiens (Human) negative regulation of centrosome duplication [GO:0010826]; regulation of protein catabolic process [GO:0042176] GO:0005737; GO:0005813; GO:0010826; GO:0042176 22055 XM_029348325.2 50 47 32 23 37 NA NA NA NA NA NA 22056 XM_044314534.1 23 23 22 44 24 NA NA NA NA NA NA 22057 XM_044308159.1 193 0 0 132 226 NA NA NA NA NA NA 22058 XM_029337392.2 25 5 85 7 80 Q5ZK40 1.89e-132 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 Gallus gallus (Chicken) hepatocyte differentiation [GO:0070365]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of histone H3-K9 dimethylation [GO:1900110]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; nervous system development [GO:0007399]; nucleosome disassembly [GO:0006337]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of glucose mediated signaling pathway [GO:1902661]; positive regulation of histone H3-K9 acetylation [GO:2000617]; positive regulation of histone H4 acetylation [GO:0090240]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901838]; regulation of transcription by RNA polymerase II [GO:0006357]; single stranded viral RNA replication via double stranded DNA intermediate [GO:0039692] GO:0000228; GO:0001164; GO:0001650; GO:0002039; GO:0003677; GO:0003712; GO:0003713; GO:0005634; GO:0005654; GO:0006337; GO:0006357; GO:0007399; GO:0008285; GO:0016514; GO:0030957; GO:0035060; GO:0039692; GO:0042802; GO:0043073; GO:0043923; GO:0045944; GO:0051091; GO:0070365; GO:0071564; GO:0071565; GO:0090240; GO:1900110; GO:1900113; GO:1901838; GO:1902661; GO:2000617 22059 XM_044314752.1 0 17 0 0 0 NA NA NA NA NA NA 22060 XM_044322684.1 19 50 21 55 10 NA NA NA NA NA NA 22061 XM_044309342.1 0 0 0 0 6 NA NA NA NA NA NA 22062 XM_044310533.1 159 91 120 0 50 NA NA NA NA NA NA 22063 XM_029348761.2 1167 279 931 968 823 Q9EQJ0 2.76e-162 Two pore calcium channel protein 1 (Voltage-dependent calcium channel protein TPC1) Mus musculus (Mouse) endocytosis involved in viral entry into host cell [GO:0075509]; positive regulation of autophagy [GO:0010508]; regulation of ion transmembrane transport [GO:0034765]; sodium ion transmembrane transport [GO:0035725] GO:0005244; GO:0005248; GO:0005765; GO:0010008; GO:0010508; GO:0015280; GO:0016020; GO:0019905; GO:0031901; GO:0034765; GO:0035725; GO:0036019; GO:0042802; GO:0042803; GO:0055038; GO:0072345; GO:0075509; GO:0080025; GO:0097682 22064 XM_029341149.2 54439 53578 34982 47065 32802 P01122 2.26e-108 Ras-like GTP-binding protein RHO Aplysia californica (California sea hare) small GTPase mediated signal transduction [GO:0007264] GO:0003924; GO:0005525; GO:0005886; GO:0007264 22065 XM_029341149.2 54439 53578 34982 47065 32802 P01122 1.07e-71 Ras-like GTP-binding protein RHO Aplysia californica (California sea hare) small GTPase mediated signal transduction [GO:0007264] GO:0003924; GO:0005525; GO:0005886; GO:0007264 22066 XM_029344217.2 182 192 184 51 317 O70422 0 General transcription factor IIH subunit 4 (Basic transcription factor 2 52 kDa subunit) (BTF2 p52) (General transcription factor IIH polypeptide 4) (TFIIH basal transcription factor complex p52 subunit) Mus musculus (Mouse) nucleotide-excision repair [GO:0006289]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; transcription by RNA polymerase II [GO:0006366] GO:0000438; GO:0000439; GO:0001671; GO:0003690; GO:0005634; GO:0005669; GO:0005675; GO:0006289; GO:0006366; GO:0016251; GO:0016607; GO:0070816 22067 XR_003827633.1 2 1 12 2 23 NA NA NA NA NA NA 22068 XM_044311384.1 0 0 0 12 0 Q4R5Y0 9.77e-35 Uncharacterized protein CFAP68 (cilia and flagella associated protein 68) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0005634 22069 XM_029327133.2 0 0 0 0 63 Q923X6 3.93e-24 Trace amine-associated receptor 7e (TaR-7e) (Trace amine receptor 7e) (Trace amine receptor 14) (TaR-14) Rattus norvegicus (Rat) NA GO:0001594; GO:0005886 22070 XM_044316963.1 41 8 9 30 38 NA NA NA NA NA NA 22071 XM_044307180.1 11 1 6 2 7 NA NA NA NA NA NA 22072 XM_029337831.2 88 125 123 81 1116 O75762 1.08e-95 Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation-sensitive protein p120) (p120) (Wasabi receptor) Homo sapiens (Human) calcium ion transmembrane transport [GO:0070588]; cell surface receptor signaling pathway [GO:0007166]; cellular calcium ion homeostasis [GO:0006874]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to organic substance [GO:0071310]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; ion transport [GO:0006811]; protein homotetramerization [GO:0051289]; response to cold [GO:0009409]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; sensory perception of pain [GO:0019233]; thermoception [GO:0050955] GO:0005262; GO:0005886; GO:0006811; GO:0006874; GO:0007166; GO:0009409; GO:0009410; GO:0010033; GO:0014070; GO:0015267; GO:0015278; GO:0019233; GO:0032421; GO:0042802; GO:0048265; GO:0050955; GO:0050966; GO:0050968; GO:0051289; GO:0070301; GO:0070588; GO:0071310; GO:0097604 22073 XM_044311075.1 28 49 19 24 25 Q8YRI1 3.12e-71 Uncharacterized WD repeat-containing protein alr3466 Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576) NA NA 22074 XM_044311075.1 28 49 19 24 25 Q8YRI1 2.52e-69 Uncharacterized WD repeat-containing protein alr3466 Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576) NA NA 22075 XM_044311075.1 28 49 19 24 25 Q8YRI1 2.76e-52 Uncharacterized WD repeat-containing protein alr3466 Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576) NA NA 22076 XM_044311075.1 28 49 19 24 25 Q8YRI1 1.32e-49 Uncharacterized WD repeat-containing protein alr3466 Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576) NA NA 22077 XM_044311075.1 28 49 19 24 25 Q8YRI1 7.57e-47 Uncharacterized WD repeat-containing protein alr3466 Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576) NA NA 22078 XM_044311075.1 28 49 19 24 25 Q8YRI1 1.92e-45 Uncharacterized WD repeat-containing protein alr3466 Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576) NA NA 22079 XM_044311075.1 28 49 19 24 25 Q8YRI1 5.26e-44 Uncharacterized WD repeat-containing protein alr3466 Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576) NA NA 22080 XM_044307850.1 72 16 39 16 0 NA NA NA NA NA NA 22081 XR_006397347.1 1153 1 1 342 364 NA NA NA NA NA NA 22082 XM_044326102.1 23 24 18 13 21 NA NA NA NA NA NA 22083 XM_029344747.2 751 538 454 854 726 Q5ZJX5 2.27e-87 MTOR-associated protein MEAK7 (MEAK7) (TBC/LysM-associated domain-containing protein 1) (TLD domain-containing protein 1) Gallus gallus (Chicken) positive regulation of protein localization to lysosome [GO:0150032]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127]; response to amino acid [GO:0043200]; response to insulin [GO:0032868]; response to nutrient levels [GO:0031667]; TOR signaling [GO:0031929] GO:0005737; GO:0005765; GO:0016020; GO:0030334; GO:0031667; GO:0031929; GO:0032868; GO:0042127; GO:0043200; GO:0150032 22084 XM_029343705.2 114 78 0 0 124 NA NA NA NA NA NA 22085 XR_003823099.2 11 30 17 16 26 NA NA NA NA NA NA 22086 XR_003824577.2 75 76 38 63 0 NA NA NA NA NA NA 22087 XM_029333483.2 217 217 36 67 486 NA NA NA NA NA NA 22088 XM_044313201.1 0 6 1 6 0 NA NA NA NA NA NA 22089 XM_044308930.1 0 0 5 0 113 NA NA NA NA NA NA 22090 XM_029337372.2 1558 1045 1142 993 1127 O95394 0 Phosphoacetylglucosamine mutase (PAGM) (EC 5.4.2.3) (Acetylglucosamine phosphomutase) (N-acetylglucosamine-phosphate mutase) (Phosphoglucomutase-3) (PGM 3) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; glucosamine metabolic process [GO:0006041]; hemopoiesis [GO:0030097]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493]; spermatogenesis [GO:0007283]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048] GO:0000287; GO:0004610; GO:0005829; GO:0005975; GO:0006041; GO:0006048; GO:0006487; GO:0006493; GO:0007283; GO:0030097 22091 XM_044313861.1 4 26 0 3 8 NA NA NA NA NA NA 22092 XM_044322157.1 116 28 42 174 279 NA NA NA NA NA NA 22093 XM_029326653.2 111 7 89 21 419 NA NA NA NA NA NA 22094 XR_006396175.1 60 190 21 29 78 Q5DU56 4.87e-28 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22095 XR_006396175.1 60 190 21 29 78 Q5DU56 4.87e-28 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22096 XR_006396175.1 60 190 21 29 78 Q5DU56 9e-27 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22097 XR_006396175.1 60 190 21 29 78 Q5DU56 9e-27 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22098 XR_006396175.1 60 190 21 29 78 Q5DU56 2.87e-23 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22099 XR_006396175.1 60 190 21 29 78 Q5DU56 2.65e-21 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22100 XM_044323260.1 6 326 178 271 105 Q9JM13 2.5e-105 Rab5 GDP/GTP exchange factor (Rabex-5) Mus musculus (Mouse) dendritic transport [GO:0098935]; establishment of localization in cell [GO:0051649]; Kit signaling pathway [GO:0038109]; mast cell degranulation [GO:0043303]; mast cell migration [GO:0097531]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of Kit signaling pathway [GO:1900235]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of mast cell activation [GO:0033004]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; negative regulation of receptor-mediated endocytosis [GO:0048261]; protein phosphorylation [GO:0006468]; protein targeting to membrane [GO:0006612]; Ras protein signal transduction [GO:0007265]; receptor-mediated endocytosis [GO:0006898]; regulation of Fc receptor mediated stimulatory signaling pathway [GO:0060368] GO:0001933; GO:0002686; GO:0003677; GO:0005085; GO:0005730; GO:0005769; GO:0005829; GO:0006468; GO:0006612; GO:0006898; GO:0007265; GO:0008270; GO:0030139; GO:0030425; GO:0031267; GO:0031982; GO:0032715; GO:0032764; GO:0033004; GO:0038109; GO:0043303; GO:0043305; GO:0046580; GO:0048261; GO:0050728; GO:0051649; GO:0055037; GO:0060368; GO:0061630; GO:0097531; GO:0098935; GO:1900235 22101 XM_044316936.1 357 298 184 318 152 Q6NUD0 1.29e-54 Methylosome protein 50 (MEP-50) (WD repeat-containing protein 77) Xenopus laevis (African clawed frog) NA GO:0005829; GO:0034709; GO:0035097 22102 XR_006396819.1 1018 1678 2126 2327 2541 NA NA NA NA NA NA 22103 XM_044328604.1 29 26 11 20 0 P18870 1.78e-32 Transcription factor Jun (Proto-oncogene c-Jun) (Transcription factor AP-1 subunit Jun) Gallus gallus (Chicken) positive regulation by host of viral transcription [GO:0043923]; positive regulation of cell growth [GO:0030307]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000976; GO:0000978; GO:0000981; GO:0005634; GO:0005667; GO:0006357; GO:0030307; GO:0042127; GO:0043923; GO:0045944; GO:0051726 22104 XM_044321349.1 61 34 0 31 5 Q13416 2.67e-111 Origin recognition complex subunit 2 Homo sapiens (Human) DNA replication initiation [GO:0006270]; negative regulation of transcription by RNA polymerase II [GO:0000122] GO:0000122; GO:0000781; GO:0000792; GO:0000808; GO:0000939; GO:0003688; GO:0005634; GO:0005654; GO:0005664; GO:0005813; GO:0006270; GO:0016020 22105 XM_029358737.2 32 10 9 0 15 NA NA NA NA NA NA 22106 XR_003827135.2 264 97 225 182 9 Q99020 1.96e-49 Heterogeneous nuclear ribonucleoprotein A/B (hnRNP A/B) (CArG-binding factor-A) (CBF-A) Mus musculus (Mouse) epithelial to mesenchymal transition [GO:0001837]; mRNA modification [GO:0016556]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA demethylation [GO:1901537]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of cellular localization [GO:0060341]; regulation of gene expression [GO:0010468]; regulation of intracellular mRNA localization [GO:1904580] GO:0000122; GO:0001837; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0010468; GO:0016556; GO:0030425; GO:0044877; GO:0045293; GO:0045893; GO:0060341; GO:0071598; GO:0090575; GO:0099523; GO:1901537; GO:1904580; GO:1990124; GO:1990837; GO:1990904; GO:2000623 22107 XM_044324184.1 1770 184 498 2 129 Q28IE5 6.64e-137 Omega-amidase NIT2 (EC 3.5.1.3) (Nitrilase homolog 2) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) nitrogen compound metabolic process [GO:0006807] GO:0005737; GO:0006807; GO:0050152; GO:0106008 22108 XM_044321237.1 46 16 23 87 49 NA NA NA NA NA NA 22109 XM_044309677.1 23 17 10 246 18 NA NA NA NA NA NA 22110 XM_044326834.1 28 1 12 21 0 NA NA NA NA NA NA 22111 XM_029348774.2 1318 1387 1123 1020 1304 Q5RDN9 3.45e-73 Protein yippee-like 2 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0005730; GO:0046872 22112 XR_006393002.1 41 2 25 5 151 NA NA NA NA NA NA 22113 XM_029333940.2 1416 1000 327 1130 1360 P23913 1.78e-107 Delta(14)-sterol reductase LBR (Delta-14-SR) (EC 1.3.1.70) (3-beta-hydroxysterol Delta (14)-reductase) (C-14 sterol reductase) (C14SR) (Integral nuclear envelope inner membrane protein) (Lamin-B receptor) (Sterol C14-reductase) Gallus gallus (Chicken) cholesterol biosynthetic process [GO:0006695]; neutrophil differentiation [GO:0030223]; sterol biosynthetic process [GO:0016126] GO:0003677; GO:0005634; GO:0005637; GO:0005737; GO:0005789; GO:0006695; GO:0016126; GO:0016627; GO:0030223; GO:0050613; GO:0070402 22114 XM_044314150.1 20 26 7 30 46 NA NA NA NA NA NA 22115 XR_006395167.1 10 0 9 4 41 NA NA NA NA NA NA 22116 XM_029339250.2 128 16 79 92 0 NA NA NA NA NA NA 22117 XR_006395145.1 47 109 3 16 44 NA NA NA NA NA NA 22118 XM_029338372.2 964 779 599 630 684 NA NA NA NA NA NA 22119 XM_044318439.1 32 23 27 16 51 NA NA NA NA NA NA 22120 XM_029337001.2 2238 2253 1579 2540 2541 Q28E28 4.28e-27 Protein phosphatase 1 regulatory subunit 3B Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) glycogen metabolic process [GO:0005977]; regulation of glycogen catabolic process [GO:0005981] GO:0000164; GO:0005977; GO:0005981; GO:0019888 22121 XM_029332624.2 17 0 0 2 19 P21452 1.89e-21 Substance-K receptor (SKR) (NK-2 receptor) (NK-2R) (Neurokinin A receptor) (Tachykinin receptor 2) Homo sapiens (Human) intestine smooth muscle contraction [GO:0014827]; muscle contraction [GO:0006936]; negative regulation of luteinizing hormone secretion [GO:0033685]; operant conditioning [GO:0035106]; positive regulation of acetylcholine secretion, neurotransmission [GO:0014057]; positive regulation of flagellated sperm motility [GO:1902093]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of uterine smooth muscle contraction [GO:0070474]; positive regulation of vascular permeability [GO:0043117]; prolactin secretion [GO:0070459]; response to electrical stimulus [GO:0051602]; tachykinin receptor signaling pathway [GO:0007217] GO:0004995; GO:0005886; GO:0006936; GO:0007217; GO:0014057; GO:0014827; GO:0016497; GO:0033685; GO:0035106; GO:0036126; GO:0043117; GO:0045987; GO:0051602; GO:0061827; GO:0070459; GO:0070474; GO:0097225; GO:1902093 22122 XM_029323787.2 28 59 12 48 167 P97292 1.77e-22 Histamine H2 receptor (H2R) (HH2R) (Gastric receptor I) Mus musculus (Mouse) chemical synaptic transmission [GO:0007268]; digestive tract development [GO:0048565]; epithelial cell morphogenesis [GO:0003382]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; gastric acid secretion [GO:0001696]; gastrin-induced gastric acid secretion [GO:0001698]; gland development [GO:0048732]; histamine-induced gastric acid secretion [GO:0001697]; memory [GO:0007613]; negative regulation of arachidonic acid secretion [GO:1900139]; positive regulation of vasoconstriction [GO:0045907]; regulation of synaptic plasticity [GO:0048167]; toxin transport [GO:1901998]; visual learning [GO:0008542] GO:0001696; GO:0001697; GO:0001698; GO:0003382; GO:0004969; GO:0004993; GO:0005886; GO:0007187; GO:0007268; GO:0007613; GO:0008542; GO:0016020; GO:0030425; GO:0030594; GO:0045202; GO:0045907; GO:0048167; GO:0048565; GO:0048732; GO:1900139; GO:1901363; GO:1901998 22123 XM_044317919.1 3538 2591 1671 2704 1343 Q9JIR0 1.62e-41 Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (RIMS-binding protein 1) (RIM-BP1) (TSPO-associated protein 1) Rattus norvegicus (Rat) calcium ion transmembrane transport [GO:0070588]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509] GO:0005737; GO:0005739; GO:0030156; GO:0044305; GO:0070588; GO:0098978; GO:0099509; GO:0099626 22124 XM_044317919.1 3538 2591 1671 2704 1343 Q9JIR0 3.51e-38 Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (RIMS-binding protein 1) (RIM-BP1) (TSPO-associated protein 1) Rattus norvegicus (Rat) calcium ion transmembrane transport [GO:0070588]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509] GO:0005737; GO:0005739; GO:0030156; GO:0044305; GO:0070588; GO:0098978; GO:0099509; GO:0099626 22125 XM_044320048.1 0 12 0 0 0 P51049 1.54e-29 Melatonin receptor type 1B-B (Mel-1B-R-B) (Mel1b receptor B) (Melatonin receptor Mel1b Z2.6-4) (zMel1b-1) Danio rerio (Zebrafish) (Brachydanio rerio) G protein-coupled receptor signaling pathway [GO:0007186]; rhythmic process [GO:0048511] GO:0004930; GO:0005886; GO:0007186; GO:0008502; GO:0048511 22126 XM_029331191.2 295 206 118 8 685 NA NA NA NA NA NA 22127 XM_029334249.2 70 52 127 198 377 P25931 3.45e-34 RYamide receptor (Neuropeptide Y-like receptor) (NPY-R) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218] GO:0001653; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0016020 22128 XM_029333617.2 0 17 0 2 373 A2VE55 1.37e-116 UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter (Solute carrier family 35 member D2) Bos taurus (Bovine) carbohydrate transport [GO:0008643] GO:0000139; GO:0005461; GO:0005462; GO:0005463; GO:0005794; GO:0008643; GO:0015297 22129 XM_029358204.2 3979 3132 1698 2511 2760 Q8IZN3 6.46e-149 Palmitoyltransferase ZDHHC14 (EC 2.3.1.225) (DHHC domain-containing cysteine-rich protein 14) (DHHC-14) (NEW1 domain-containing protein) (NEW1CP) (Zinc finger DHHC domain-containing protein 14) Homo sapiens (Human) peptidyl-L-cysteine S-palmitoylation [GO:0018230]; protein palmitoylation [GO:0018345]; protein targeting to membrane [GO:0006612] GO:0005783; GO:0005789; GO:0005794; GO:0006612; GO:0016409; GO:0018230; GO:0018345; GO:0019706; GO:0032580 22130 XR_006393858.1 26 28 0 1 0 NA NA NA NA NA NA 22131 XM_044321190.1 1 0 9 12 20 NA NA NA NA NA NA 22132 XM_044312243.1 1358 1432 1052 1511 1540 Q71U00 5.06e-79 S-phase kinase-associated protein 1 (Cyclin-A/CDK2-associated protein p19) (S-phase kinase-associated protein 1A) (p19A) (p19skp1) Xenopus laevis (African clawed frog) protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0006511; GO:0016567; GO:0019005; GO:0031467 22133 XR_006396771.1 285 155 205 249 57 NA NA NA NA NA NA 22134 XM_029330674.2 174 0 0 0 231 Q9I9A7 1.21e-93 DNA replication factor Cdt1 (XCDT1) Xenopus laevis (African clawed frog) DNA replication preinitiation complex assembly [GO:0071163]; regulation of DNA-templated DNA replication initiation [GO:0030174] GO:0005634; GO:0030174; GO:0031490; GO:0071163 22135 XM_044308801.1 34 0 0 0 408 NA NA NA NA NA NA 22136 XM_044306902.1 400 308 245 319 237 Q7SX99 0 Fumarate hydratase, mitochondrial (Fumarase) (EC 4.2.1.2) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; fumarate metabolic process [GO:0006106]; malate metabolic process [GO:0006108]; negative regulation of histone H3-K36 methylation [GO:0000415]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of arginine metabolic process [GO:0000821]; tricarboxylic acid cycle [GO:0006099]; urea cycle [GO:0000050] GO:0000050; GO:0000415; GO:0000821; GO:0004333; GO:0005634; GO:0005694; GO:0005739; GO:0005829; GO:0006099; GO:0006106; GO:0006108; GO:0006281; GO:0006974; GO:0045239; GO:2001034 22137 XM_029339784.2 50 14 12 15 17 NA NA NA NA NA NA 22138 XR_003826394.2 20359 17401 5823 19804 7481 NA NA NA NA NA NA 22139 XR_006396690.1 320 212 109 313 181 Q6ITT3 5.83e-35 Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C (EC 2.4.1.145) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVc) (GnT-IVc) (N-acetylglucosaminyltransferase IVc) (UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVc) Sus scrofa (Pig) protein N-linked glycosylation [GO:0006487] GO:0000139; GO:0006487; GO:0008375; GO:0008454; GO:0046872 22140 XM_044313847.1 43 60 0 150 0 NA NA NA NA NA NA 22141 XR_003827129.2 24 2608 3860 1169 1122 NA NA NA NA NA NA 22142 XM_029336895.2 0 0 0 86 277 NA NA NA NA NA NA 22143 XM_029340572.2 70 60 86 196 80 NA NA NA NA NA NA 22144 XM_029332819.2 7628 9170 5667 6843 7210 Q54E49 0 Probable ATP-dependent RNA helicase ddx6 (EC 3.6.4.13) (DEAD box protein 6) Dictyostelium discoideum (Social amoeba) mRNA processing [GO:0006397]; negative regulation of translation [GO:0017148]; P-body assembly [GO:0033962]; stress granule assembly [GO:0034063] GO:0000932; GO:0003724; GO:0003729; GO:0005524; GO:0005634; GO:0006397; GO:0010494; GO:0016887; GO:0017148; GO:0033962; GO:0034063 22145 XM_044328221.1 89 0 0 0 0 NA NA NA NA NA NA 22146 XM_044317098.1 116 20 53 132 272 Q6P0C6 4.7e-48 LHFPL tetraspan subfamily member 2a protein Danio rerio (Zebrafish) (Brachydanio rerio) development of primary female sexual characteristics [GO:0046545]; development of primary male sexual characteristics [GO:0046546]; positive regulation of fertilization [GO:1905516]; single fertilization [GO:0007338] GO:0007338; GO:0016020; GO:0046545; GO:0046546; GO:1905516 22147 XM_044322293.1 395 109 114 116 65 NA NA NA NA NA NA 22148 XM_029351114.2 192 302 185 156 93 NA NA NA NA NA NA 22149 XM_029349607.2 5 31 3 20 23 NA NA NA NA NA NA 22150 XM_044313697.1 15 2 0 8 8 NA NA NA NA NA NA 22151 XM_044328670.1 0 0 10 0 0 Q6V0K7 8.76e-50 Oncoprotein-induced transcript 3 protein (Liver-specific zona pellucida domain-containing protein) Rattus norvegicus (Rat) urate homeostasis [GO:1903118] GO:0005201; GO:0005509; GO:0005615; GO:0005635; GO:0009986; GO:1903118 22152 XM_029335687.2 39 19 24 25 29 Q06725 1.3e-71 Nuclear receptor subfamily 2 group F member 1-A (COUP transcription factor 1-A) (COUP-TFalpha-A) (zCOUP-TFI) (Seven-up related 44) (Svp[44]) (zSvp[44]) (Steroid receptor homolog SVP 44) Danio rerio (Zebrafish) (Brachydanio rerio) anatomical structure development [GO:0048856]; atrial cardiac muscle cell differentiation [GO:0055011]; cardiac atrium morphogenesis [GO:0003209]; cardiac muscle tissue development [GO:0048738]; cell differentiation [GO:0030154]; endothelial cell proliferation [GO:0001935]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; vasculature development [GO:0001944] GO:0000122; GO:0000978; GO:0001935; GO:0001944; GO:0003209; GO:0004879; GO:0005634; GO:0006357; GO:0008270; GO:0030154; GO:0045944; GO:0048738; GO:0048856; GO:0055011 22153 XM_029324158.2 860 693 522 1229 867 A0A0R4IFG5 2.8e-42 Cilia- and flagella-associated protein 53 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287] GO:0003341; GO:0005576; GO:0005879; GO:0005930; GO:0007368; GO:0060271; GO:0060287; GO:0097546 22154 XM_044313581.1 51 19 43 58 105 NA NA NA NA NA NA 22155 XM_044307305.1 252 597 61 627 251 E9PSU6 0 Pecanex-like protein 1 (Pecanex 1) (Pecanex homolog protein 1) Rattus norvegicus (Rat) NA GO:0016020 22156 XM_044307305.1 252 597 61 627 251 E9PSU6 1.15e-28 Pecanex-like protein 1 (Pecanex 1) (Pecanex homolog protein 1) Rattus norvegicus (Rat) NA GO:0016020 22157 XM_044307305.1 252 597 61 627 251 E9PSU6 6.67e-21 Pecanex-like protein 1 (Pecanex 1) (Pecanex homolog protein 1) Rattus norvegicus (Rat) NA GO:0016020 22158 XM_029337954.2 425 522 469 641 535 NA NA NA NA NA NA 22159 XM_029350253.2 236 56 42 70 65 P49961 1.55e-38 Ectonucleoside triphosphate diphosphohydrolase 1 (NTPDase 1) (EC 3.6.1.5) (Ecto-ATP diphosphohydrolase 1) (Ecto-ATPDase 1) (Ecto-ATPase 1) (Ecto-apyrase) (Lymphoid cell activation antigen) (CD antigen CD39) Homo sapiens (Human) blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; nucleoside diphosphate catabolic process [GO:0009134] GO:0004382; GO:0005524; GO:0005886; GO:0007155; GO:0007596; GO:0009134; GO:0016020; GO:0017110; GO:0045134; GO:0070062 22160 XM_044317983.1 159 8 85 24 317 NA NA NA NA NA NA 22161 XM_044309743.1 599 910 647 662 398 Q8K1T0 4.77e-49 Transmembrane protease serine 3 (EC 3.4.21.-) Mus musculus (Mouse) cellular sodium ion homeostasis [GO:0006883]; proteolysis [GO:0006508]; sensory perception of sound [GO:0007605] GO:0004252; GO:0005044; GO:0005783; GO:0005789; GO:0006508; GO:0006883; GO:0007605; GO:0017080; GO:0043025 22162 XM_044317159.1 0 0 3 0 31 NA NA NA NA NA NA 22163 XM_044322968.1 280 387 445 242 143 Q5R4G6 0 Cullin-1 (CUL-1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; cell population proliferation [GO:0008283]; protein K48-linked ubiquitination [GO:0070936]; protein monoubiquitination [GO:0006513]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0005886; GO:0006513; GO:0006915; GO:0008283; GO:0009887; GO:0019005; GO:0031146; GO:0031625; GO:0070936; GO:1990452 22164 XR_006394717.1 0 0 0 1 27 NA NA NA NA NA NA 22165 XM_029342599.2 466 308 150 466 367 A2RT91 0 Ankyrin and armadillo repeat-containing protein Mus musculus (Mouse) NA GO:0016020 22166 XM_029347837.2 1074 748 783 997 907 Q7SXN4 1.63e-160 Cytoplasmic polyadenylation element-binding protein 4 (CPE-BP4) (CPE-binding protein 4) (CPEB-4) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to amino acid stimulus [GO:0071230]; cellular response to decreased oxygen levels [GO:0036294]; cellular response to glucose starvation [GO:0042149]; ionotropic glutamate receptor signaling pathway [GO:0035235]; negative regulation of cytoplasmic translation [GO:2000766]; negative regulation of neuron apoptotic process [GO:0043524]; response to ischemia [GO:0002931] GO:0000900; GO:0002931; GO:0003730; GO:0005634; GO:0005737; GO:0005783; GO:0008135; GO:0014069; GO:0030425; GO:0030426; GO:0035235; GO:0036294; GO:0042149; GO:0043005; GO:0043022; GO:0043197; GO:0043524; GO:0045202; GO:0048471; GO:0071230; GO:1990124; GO:2000766 22167 XM_029333601.2 0 40 0 0 0 NA NA NA NA NA NA 22168 XR_003823297.2 1967 2915 1670 2611 894 NA NA NA NA NA NA 22169 XM_044321899.1 3115 1561 1932 2847 3424 Q9NZM3 0 Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein) Homo sapiens (Human) cell differentiation [GO:0030154]; clathrin-dependent synaptic vesicle endocytosis [GO:0150007]; endocytosis [GO:0006897]; endosomal transport [GO:0016197]; positive regulation of dendrite extension [GO:1903861] GO:0005085; GO:0005509; GO:0005813; GO:0005829; GO:0005905; GO:0006897; GO:0016197; GO:0030154; GO:0060090; GO:0070062; GO:0098793; GO:0150007; GO:1903861 22170 XM_044321899.1 3115 1561 1932 2847 3424 Q9NZM3 8.24e-26 Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein) Homo sapiens (Human) cell differentiation [GO:0030154]; clathrin-dependent synaptic vesicle endocytosis [GO:0150007]; endocytosis [GO:0006897]; endosomal transport [GO:0016197]; positive regulation of dendrite extension [GO:1903861] GO:0005085; GO:0005509; GO:0005813; GO:0005829; GO:0005905; GO:0006897; GO:0016197; GO:0030154; GO:0060090; GO:0070062; GO:0098793; GO:0150007; GO:1903861 22171 XM_044321899.1 3115 1561 1932 2847 3424 Q9NZM3 4.32e-24 Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein) Homo sapiens (Human) cell differentiation [GO:0030154]; clathrin-dependent synaptic vesicle endocytosis [GO:0150007]; endocytosis [GO:0006897]; endosomal transport [GO:0016197]; positive regulation of dendrite extension [GO:1903861] GO:0005085; GO:0005509; GO:0005813; GO:0005829; GO:0005905; GO:0006897; GO:0016197; GO:0030154; GO:0060090; GO:0070062; GO:0098793; GO:0150007; GO:1903861 22172 XM_029340673.2 332 250 226 302 337 P27088 5.26e-71 DNA repair protein complementing XP-A cells homolog (Xeroderma pigmentosum group A-complementing protein homolog) Xenopus laevis (African clawed frog) nucleotide-excision repair [GO:0006289]; UV-damage excision repair [GO:0070914] GO:0003684; GO:0003690; GO:0005634; GO:0005662; GO:0006289; GO:0008270; GO:0070914; GO:1990391 22173 XM_044315200.1 32 15 46 21 110 NA NA NA NA NA NA 22174 XM_044312884.1 42 20 6 51 21 NA NA NA NA NA NA 22175 XM_029344887.2 48 8 41 40 109 NA NA NA NA NA NA 22176 XM_029350982.2 21 0 0 0 0 Q8IZU8 0 Dermatan-sulfate epimerase-like protein (EC 5.1.-.-) Homo sapiens (Human) chondroitin sulfate metabolic process [GO:0030204]; dermatan sulfate biosynthetic process [GO:0030208]; dermatan sulfate metabolic process [GO:0030205] GO:0000139; GO:0008146; GO:0030204; GO:0030205; GO:0030208; GO:0047757 22177 XM_044322198.1 98 0 49 0 48 NA NA NA NA NA NA 22178 XM_029343878.2 4316 2877 2125 4450 3755 Q9JIH7 2.26e-149 Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase lysine-deficient 1) (Protein kinase with no lysine 1) Rattus norvegicus (Rat) cation homeostasis [GO:0055080]; cellular chloride ion homeostasis [GO:0030644]; cellular response to calcium ion [GO:0071277]; cellular response to chemokine [GO:1990869]; chemokine (C-C motif) ligand 21 signaling pathway [GO:0038116]; intracellular signal transduction [GO:0035556]; ion homeostasis [GO:0050801]; ion transport [GO:0006811]; lymphocyte migration into lymph node [GO:0097022]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of cell-cell adhesion mediated by integrin [GO:0033633]; negative regulation of GTPase activity [GO:0034260]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of kinase activity [GO:0033673]; negative regulation of leukocyte cell-cell adhesion [GO:1903038]; negative regulation of pancreatic juice secretion [GO:0090188]; negative regulation of sodium ion transport [GO:0010766]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of potassium ion import across plasma membrane [GO:1903288]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of systemic arterial blood pressure [GO:0003084]; positive regulation of T cell chemotaxis [GO:0010820]; potassium ion homeostasis [GO:0055075]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of blood pressure [GO:0008217]; regulation of cation transmembrane transport [GO:1904062]; regulation of sodium ion transmembrane transport [GO:1902305]; regulation of sodium ion transport [GO:0002028]; signal transduction [GO:0007165]; sodium ion transmembrane transport [GO:0035725]; T cell receptor signaling pathway [GO:0050852] GO:0000287; GO:0002028; GO:0003084; GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0005829; GO:0006468; GO:0006811; GO:0007165; GO:0008217; GO:0010766; GO:0010820; GO:0016020; GO:0018105; GO:0018107; GO:0019869; GO:0019870; GO:0019901; GO:0019902; GO:0030291; GO:0030295; GO:0030644; GO:0032991; GO:0033633; GO:0033673; GO:0034115; GO:0034260; GO:0035556; GO:0035725; GO:0038116; GO:0046777; GO:0050801; GO:0050804; GO:0050852; GO:0055075; GO:0055080; GO:0071277; GO:0090188; GO:0090263; GO:0097022; GO:0098982; GO:0106310; GO:1902305; GO:1903038; GO:1903288; GO:1904062; GO:1990869; GO:2000651 22179 XM_029355982.2 0 52 91 0 0 NA NA NA NA NA NA 22180 XM_029340137.2 7033 8875 4711 8514 6189 Q99LQ7 1.05e-87 Plasmanylethanolamine desaturase (EC 1.14.19.77) (Plasmanylethanolamine desaturase 1) (Transmembrane protein 189) Mus musculus (Mouse) ether lipid biosynthetic process [GO:0008611]; fatty acid metabolic process [GO:0006631] GO:0005783; GO:0005789; GO:0006631; GO:0008611; GO:0016491; GO:0050207 22181 XM_044323820.1 322 309 268 597 407 Q15434 5.5e-77 RNA-binding motif, single-stranded-interacting protein 2 (Suppressor of CDC2 with RNA-binding motif 3) Homo sapiens (Human) RNA processing [GO:0006396] GO:0003723; GO:0003730; GO:0005634; GO:0005829; GO:0006396; GO:0008143; GO:0008266; GO:1990904 22182 XM_029331116.2 1270 1193 1245 1477 2445 Q8TEM1 0 Nuclear pore membrane glycoprotein 210 (Nuclear pore protein gp210) (Nuclear envelope pore membrane protein POM 210) (POM210) (Nucleoporin Nup210) (Pore membrane protein of 210 kDa) Homo sapiens (Human) mRNA transport [GO:0051028]; nucleocytoplasmic transport [GO:0006913]; protein transport [GO:0015031] GO:0005635; GO:0005643; GO:0005789; GO:0006913; GO:0015031; GO:0016020; GO:0031965; GO:0051028 22183 XM_029339872.2 378 320 111 62 302 Q9UJW0 2.37e-115 Dynactin subunit 4 (Dyn4) (Dynactin subunit p62) Homo sapiens (Human) NA GO:0000776; GO:0000922; GO:0001725; GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0005868; GO:0005869; GO:0005925; GO:0005938; GO:0030017; GO:0047485 22184 XM_044307380.1 84 66 87 98 141 F8W2M1 4.12e-46 E3 ubiquitin-protein ligase HACE1 (EC 2.3.2.26) (HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1) (HECT-type E3 ubiquitin transferase HACE1) Danio rerio (Zebrafish) (Brachydanio rerio) atrioventricular valve formation [GO:0003190]; cardiac ventricle morphogenesis [GO:0003208]; cell cycle [GO:0007049]; Golgi organization [GO:0007030]; heart looping [GO:0001947]; membrane fusion [GO:0061025]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of cell migration [GO:0030334]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000139; GO:0000209; GO:0001947; GO:0003190; GO:0003208; GO:0004842; GO:0005634; GO:0005737; GO:0005783; GO:0006511; GO:0007030; GO:0007049; GO:0016567; GO:0030334; GO:0031267; GO:0032580; GO:0043161; GO:0061025; GO:0061630; GO:0070936; GO:1903427 22185 XM_044325374.1 2006 1021 1259 1346 1619 Q9C0D7 9.66e-86 Probable ribonuclease ZC3H12C (EC 3.1.-.-) (MCP-induced protein 3) (Zinc finger CCCH domain-containing protein 12C) Homo sapiens (Human) RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502] GO:0003729; GO:0004521; GO:0005634; GO:0036464; GO:0046872; GO:0090502 22186 XM_044316733.1 232 275 226 464 332 NA NA NA NA NA NA 22187 XM_044321851.1 25 11 23 17 23 NA NA NA NA NA NA 22188 XM_044320865.1 0 0 0 0 8 G5EBX9 9.19e-179 Serine/threonine-protein phosphatase with EF-hands pef-1 (CePPEF) (EC 3.1.3.16) (Phosphatase with EF hands 1) Caenorhabditis elegans detection of stimulus involved in sensory perception [GO:0050906] GO:0004722; GO:0005506; GO:0005509; GO:0005634; GO:0005829; GO:0005886; GO:0005929; GO:0017018; GO:0030145; GO:0030424; GO:0030425; GO:0043025; GO:0043204; GO:0050906 22189 XM_029329308.2 20 20 2 29 79 NA NA NA NA NA NA 22190 XM_029351284.2 889 535 383 406 381 NA NA NA NA NA NA 22191 XM_044323017.1 1326 1244 984 3716 3484 P02466 5.01e-46 Collagen alpha-2(I) chain (Alpha-2 type I collagen) Rattus norvegicus (Rat) blood vessel development [GO:0001568]; bone mineralization [GO:0030282]; cellular response to amino acid stimulus [GO:0071230]; cellular response to organic substance [GO:0071310]; cellular response to retinoic acid [GO:0071300]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; extracellular matrix assembly [GO:0085029]; extracellular matrix organization [GO:0030198]; protein heterotrimerization [GO:0070208]; regulation of blood pressure [GO:0008217]; response to norepinephrine [GO:0071873]; Rho protein signal transduction [GO:0007266]; skeletal system development [GO:0001501]; skin morphogenesis [GO:0043589]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001501; GO:0001568; GO:0002020; GO:0005201; GO:0005576; GO:0005581; GO:0005584; GO:0005615; GO:0007179; GO:0007266; GO:0008217; GO:0030198; GO:0030199; GO:0030282; GO:0030674; GO:0031012; GO:0032963; GO:0042802; GO:0043589; GO:0046332; GO:0046872; GO:0048407; GO:0062023; GO:0070208; GO:0071230; GO:0071300; GO:0071310; GO:0071873; GO:0085029; GO:0097067 22192 XM_044312256.1 0 0 14 3 6 NA NA NA NA NA NA 22193 XM_029338629.2 51 408 26 94 23 NA NA NA NA NA NA 22194 XM_029347408.2 13 0 1 14 32 P70031 2.11e-34 Cholecystokinin receptor (CCK-XLR) Xenopus laevis (African clawed frog) NA GO:0004930; GO:0005886 22195 XM_044323989.1 882 1067 602 2072 2453 P35546 3.88e-80 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; anatomical structure morphogenesis [GO:0009653]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006919; GO:0007156; GO:0007158; GO:0007169; GO:0007399; GO:0009410; GO:0009653; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030182; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0098797; GO:2001241 22196 XM_044324193.1 1156 1200 1077 1481 1534 Q9HAV4 0 Exportin-5 (Exp5) (Ran-binding protein 21) Homo sapiens (Human) miRNA metabolic process [GO:0010586]; positive regulation of post-transcriptional gene silencing by RNA [GO:1900370]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; RNA export from nucleus [GO:0006405] GO:0000049; GO:0003723; GO:0003729; GO:0005049; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006405; GO:0006611; GO:0010586; GO:0016442; GO:0031267; GO:0035281; GO:0042565; GO:0070883; GO:1900370; GO:1905172 22197 XM_029342983.2 259 148 308 196 436 Q2KNE5 5.87e-45 Melanopsin-A (Mammalian-like melanopsin) (Melanopsin-M) (Opsin-4-A) (Opsin-4M) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to light stimulus [GO:0071482]; G protein-coupled receptor signaling pathway [GO:0007186]; phototransduction [GO:0007602]; visual perception [GO:0007601] GO:0005886; GO:0007186; GO:0007601; GO:0007602; GO:0008020; GO:0009881; GO:0071482 22198 XM_029340626.2 889 714 134 453 249 Q5VXJ0 4.94e-108 Lipase member K (EC 3.1.1.-) (Lipase-like abhydrolase domain-containing protein 2) Homo sapiens (Human) cornification [GO:0070268]; lipid catabolic process [GO:0016042] GO:0004465; GO:0005576; GO:0016042; GO:0043231; GO:0070268 22199 XM_029349987.2 25 0 12 3 18 NA NA NA NA NA NA 22200 XR_003828303.2 872 564 305 711 397 Q9XTR8 1.3e-31 Lipase ZK262.3 (EC 3.1.1.-) Caenorhabditis elegans lipid catabolic process [GO:0016042] GO:0005576; GO:0016042; GO:0016787 22201 XM_029357093.2 1 3 8 10 7 NA NA NA NA NA NA 22202 XR_006397406.1 6 0 0 0 0 NA NA NA NA NA NA 22203 XM_029355665.2 0 0 0 0 124 A4IFB6 0 CCR4-NOT transcription complex subunit 10 Bos taurus (Bovine) mRNA catabolic process [GO:0006402]; negative regulation of translation [GO:0017148] GO:0006402; GO:0017148; GO:0030014 22204 XM_029331278.2 261 224 218 402 771 Q14192 7.51e-71 Four and a half LIM domains protein 2 (FHL-2) (LIM domain protein DRAL) (Skeletal muscle LIM-protein 3) (SLIM-3) Homo sapiens (Human) atrial cardiac muscle cell development [GO:0055014]; heart trabecula formation [GO:0060347]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of transcription by RNA polymerase II [GO:0000122]; osteoblast differentiation [GO:0001649]; response to hormone [GO:0009725]; ventricular cardiac muscle cell development [GO:0055015] GO:0000122; GO:0001649; GO:0003712; GO:0003714; GO:0005634; GO:0005654; GO:0005925; GO:0008134; GO:0009725; GO:0030018; GO:0042802; GO:0043066; GO:0043425; GO:0046872; GO:0055014; GO:0055015; GO:0060347; GO:0070885 22205 XM_029331278.2 261 224 218 402 771 Q14192 2.96e-30 Four and a half LIM domains protein 2 (FHL-2) (LIM domain protein DRAL) (Skeletal muscle LIM-protein 3) (SLIM-3) Homo sapiens (Human) atrial cardiac muscle cell development [GO:0055014]; heart trabecula formation [GO:0060347]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of transcription by RNA polymerase II [GO:0000122]; osteoblast differentiation [GO:0001649]; response to hormone [GO:0009725]; ventricular cardiac muscle cell development [GO:0055015] GO:0000122; GO:0001649; GO:0003712; GO:0003714; GO:0005634; GO:0005654; GO:0005925; GO:0008134; GO:0009725; GO:0030018; GO:0042802; GO:0043066; GO:0043425; GO:0046872; GO:0055014; GO:0055015; GO:0060347; GO:0070885 22206 XM_029331278.2 261 224 218 402 771 Q14192 2.69e-22 Four and a half LIM domains protein 2 (FHL-2) (LIM domain protein DRAL) (Skeletal muscle LIM-protein 3) (SLIM-3) Homo sapiens (Human) atrial cardiac muscle cell development [GO:0055014]; heart trabecula formation [GO:0060347]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of transcription by RNA polymerase II [GO:0000122]; osteoblast differentiation [GO:0001649]; response to hormone [GO:0009725]; ventricular cardiac muscle cell development [GO:0055015] GO:0000122; GO:0001649; GO:0003712; GO:0003714; GO:0005634; GO:0005654; GO:0005925; GO:0008134; GO:0009725; GO:0030018; GO:0042802; GO:0043066; GO:0043425; GO:0046872; GO:0055014; GO:0055015; GO:0060347; GO:0070885 22207 XM_029333637.2 364 0 254 151 30 Q90693 1.54e-138 Protein patched homolog 1 (PTC) (PTC1) Gallus gallus (Chicken) negative regulation of smoothened signaling pathway [GO:0045879]; smoothened signaling pathway [GO:0007224] GO:0005119; GO:0005886; GO:0007224; GO:0008158; GO:0045879; GO:0097108 22208 XM_029333637.2 364 0 254 151 30 Q90693 5e-126 Protein patched homolog 1 (PTC) (PTC1) Gallus gallus (Chicken) negative regulation of smoothened signaling pathway [GO:0045879]; smoothened signaling pathway [GO:0007224] GO:0005119; GO:0005886; GO:0007224; GO:0008158; GO:0045879; GO:0097108 22209 XM_029357256.2 135 0 18 152 26 NA NA NA NA NA NA 22210 XM_029348402.2 86 44 44 69 152 NA NA NA NA NA NA 22211 XM_044308284.1 74 52 79 47 184 Q07598 0 Sterol carrier protein 2 (SCP-2) (Acetyl-CoA C-myristoyltransferase) (EC 2.3.1.155) (Non-specific lipid-transfer protein) (NSL-TP) (Propanoyl-CoA C-acyltransferase) (EC 2.3.1.176) (SCP-2/3-oxoacyl-CoA thiolase) (SCP-2/thiolase) (EC 2.3.1.16) (SCP-chi) (SCPX) (Sterol carrier protein X) (SCP-X) Gallus gallus (Chicken) bile acid metabolic process [GO:0008206]; fatty acid beta-oxidation [GO:0006635]; lipid transport [GO:0006869]; positive regulation of intracellular cholesterol transport [GO:0032385] GO:0003988; GO:0005737; GO:0005739; GO:0005777; GO:0005782; GO:0005783; GO:0006635; GO:0006869; GO:0008206; GO:0008289; GO:0032385; GO:0033814; GO:0050632; GO:0050633; GO:0120019; GO:0120020 22212 XM_029353986.2 1 4 22 13 22 NA NA NA NA NA NA 22213 XR_006392265.1 84 18 0 63 0 NA NA NA NA NA NA 22214 XM_044308052.1 130 171 116 150 98 Q9YGL3 6.51e-99 Nuclear receptor subfamily 2 group E member 1 (Nuclear receptor TLX) (Protein tailless homolog) (Tll) Oryzias latipes (Japanese rice fish) (Japanese killifish) anatomical structure development [GO:0048856]; cell differentiation [GO:0030154]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000978; GO:0004879; GO:0005634; GO:0006357; GO:0008270; GO:0030154; GO:0048856 22215 XM_044325339.1 18 22 12 4 28 A6QLU6 3.9e-71 Adhesion G-protein coupled receptor D1 (G-protein coupled receptor 133) Bos taurus (Bovine) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0005886; GO:0007166; GO:0007186; GO:0007189 22216 XM_029358208.2 0 50 54 0 0 NA NA NA NA NA NA 22217 XM_029323925.2 910 881 731 942 1155 NA NA NA NA NA NA 22218 XM_029332800.2 46 63 79 71 138 Q9I8C7 1.45e-96 Neuronal acetylcholine receptor subunit alpha-10 (Alpha 10 nAChR) (Nicotinic acetylcholine receptor subunit alpha-10) (NACHR alpha-10) Gallus gallus (Chicken) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; response to auditory stimulus [GO:0010996]; signal transduction [GO:0007165] GO:0004888; GO:0005231; GO:0005262; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0010996; GO:0022848; GO:0030594; GO:0034220; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051899; GO:1904315 22219 XR_006393359.1 27 8 0 0 0 NA NA NA NA NA NA 22220 XM_029324979.2 5 0 2 26 14 NA NA NA NA NA NA 22221 XM_044315495.1 2 10 0 5 14 NA NA NA NA NA NA 22222 XM_044317836.1 56 46 94 55 57 NA NA NA NA NA NA 22223 XM_029353007.2 275 515 235 595 412 P52493 4.16e-25 Ubiquitin-conjugating enzyme E2 2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 2) (Mutagen-sensitive protein 8) (Ubiquitin carrier protein ubc2) (Ubiquitin-protein ligase ubc2) Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) cytoplasm protein quality control by the ubiquitin-proteasome system [GO:0071629]; DNA repair [GO:0006281]; DNA-templated transcription termination [GO:0006353]; double-strand break repair via homologous recombination [GO:0000724]; error-free postreplication DNA repair [GO:0042275]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; histone monoubiquitination [GO:0010390]; histone ubiquitination [GO:0016574]; meiotic DNA double-strand break formation [GO:0042138]; mitotic G1 DNA damage checkpoint signaling [GO:0031571]; negative regulation of SREBP signaling pathway [GO:2000639]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; regulation of dipeptide transport [GO:0090089]; sporulation resulting in formation of a cellular spore [GO:0030435]; stress-induced homeostatically regulated protein degradation pathway [GO:0120174]; subtelomeric heterochromatin formation [GO:0031509]; telomere maintenance via recombination [GO:0000722]; transcription by RNA polymerase II [GO:0006366]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process via the N-end rule pathway [GO:0071596] GO:0000209; GO:0000722; GO:0000724; GO:0000781; GO:0003697; GO:0005524; GO:0005634; GO:0005737; GO:0006281; GO:0006353; GO:0006366; GO:0010390; GO:0016574; GO:0017116; GO:0030433; GO:0030435; GO:0031509; GO:0031571; GO:0033503; GO:0042138; GO:0042275; GO:0042276; GO:0043161; GO:0061631; GO:0070534; GO:0070628; GO:0070987; GO:0071596; GO:0071629; GO:0090089; GO:0097505; GO:0120174; GO:1990302; GO:1990303; GO:1990304; GO:1990305; GO:2000639 22224 XM_029353632.2 13355 12823 9221 11450 7244 Q00277 6.25e-64 Glutathione peroxidase (GPX) (EC 1.11.1.9) Schistosoma mansoni (Blood fluke) response to oxidative stress [GO:0006979] GO:0004602; GO:0006979 22225 XM_029324510.2 0 0 0 0 74 NA NA NA NA NA NA 22226 XM_029334217.2 0 19 0 0 158 P25931 2.4e-33 RYamide receptor (Neuropeptide Y-like receptor) (NPY-R) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218] GO:0001653; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0016020 22227 XR_006397685.1 207 154 91 310 277 NA NA NA NA NA NA 22228 XM_029350312.2 29 12 14 22 31 Q28044 9.59e-23 Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor) Bos taurus (Bovine) activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; bone resorption [GO:0045453]; brown fat cell differentiation [GO:0050873]; cellular response to amyloid-beta [GO:1904646]; desensitization of G protein-coupled receptor signaling pathway by arrestin [GO:0002032]; diet induced thermogenesis [GO:0002024]; heat generation [GO:0031649]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of smooth muscle contraction [GO:0045986]; norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0002025]; positive regulation of AMPA receptor activity [GO:2000969]; positive regulation of autophagosome maturation [GO:1901098]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of lipophagy [GO:1904504]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mini excitatory postsynaptic potential [GO:0061885]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor-mediated endocytosis [GO:0006898]; regulation of sodium ion transport [GO:0002028]; response to cold [GO:0009409]; smooth muscle contraction [GO:0006939]; transcription by RNA polymerase II [GO:0006366] GO:0001540; GO:0002024; GO:0002025; GO:0002028; GO:0002032; GO:0004930; GO:0004941; GO:0005634; GO:0005769; GO:0005794; GO:0005886; GO:0006366; GO:0006898; GO:0006939; GO:0007190; GO:0008179; GO:0009409; GO:0010739; GO:0015459; GO:0016324; GO:0030501; GO:0031649; GO:0040015; GO:0042803; GO:0043235; GO:0043410; GO:0044877; GO:0045453; GO:0045944; GO:0045986; GO:0050873; GO:0051380; GO:0061885; GO:0071880; GO:0071902; GO:0098992; GO:0120162; GO:1901098; GO:1904504; GO:1904646; GO:2000969 22229 XM_029349729.2 1126 843 701 881 649 Q9CQ02 2.58e-68 COMM domain-containing protein 4 Mus musculus (Mouse) NA GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0043231 22230 XM_044323884.1 0 0 216 2 0 NA NA NA NA NA NA 22231 XR_006393182.1 226 0 121 503 188 NA NA NA NA NA NA 22232 XM_044310896.1 2 0 2 41 62 Q8N2S1 7.62e-83 Latent-transforming growth factor beta-binding protein 4 (LTBP-4) Homo sapiens (Human) elastic fiber assembly [GO:0048251]; hormone secretion [GO:0046879]; protein folding [GO:0006457]; regulation of cell growth [GO:0001558]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001527; GO:0001558; GO:0005024; GO:0005178; GO:0005509; GO:0005539; GO:0005576; GO:0005615; GO:0006457; GO:0007179; GO:0017015; GO:0031012; GO:0046879; GO:0048251; GO:0050431; GO:0062023 22233 XM_044310896.1 2 0 2 41 62 Q8N2S1 1.42e-81 Latent-transforming growth factor beta-binding protein 4 (LTBP-4) Homo sapiens (Human) elastic fiber assembly [GO:0048251]; hormone secretion [GO:0046879]; protein folding [GO:0006457]; regulation of cell growth [GO:0001558]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001527; GO:0001558; GO:0005024; GO:0005178; GO:0005509; GO:0005539; GO:0005576; GO:0005615; GO:0006457; GO:0007179; GO:0017015; GO:0031012; GO:0046879; GO:0048251; GO:0050431; GO:0062023 22234 XR_006392652.1 0 0 0 7 0 NA NA NA NA NA NA 22235 XM_029326903.2 1074 849 646 984 840 Q9VR81 1.04e-140 N-acetylglucosamine-6-phosphate deacetylase (GlcNAc 6-P deacetylase) (EC 3.5.1.25) Drosophila melanogaster (Fruit fly) carbohydrate metabolic process [GO:0005975]; N-acetylglucosamine catabolic process [GO:0006046] GO:0005975; GO:0006046; GO:0008448; GO:0046872; GO:0047419 22236 XM_044310561.1 236 154 92 65 123 NA NA NA NA NA NA 22237 XM_044328137.1 421 182 191 296 503 Q6PHN1 1.25e-83 Coiled-coil domain-containing protein 57 Mus musculus (Mouse) centriole replication [GO:0007099]; cilium assembly [GO:0060271]; G2/M transition of mitotic cell cycle [GO:0000086]; microtubule nucleation [GO:0007020]; positive regulation of mitotic cell cycle [GO:0045931] GO:0000086; GO:0005737; GO:0005813; GO:0005814; GO:0005876; GO:0007020; GO:0007099; GO:0034451; GO:0045931; GO:0060271 22238 XM_044313028.1 4306 789 672 2165 467 Q96DM1 3.85e-63 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 22239 XM_029355287.2 2112 1362 1069 2157 1878 Q9WUA2 0 Phenylalanine--tRNA ligase beta subunit (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase beta subunit) (PheRS) Mus musculus (Mouse) phenylalanyl-tRNA aminoacylation [GO:0006432]; protein heterotetramerization [GO:0051290] GO:0000287; GO:0003723; GO:0004826; GO:0005524; GO:0006432; GO:0009328; GO:0051290 22240 XM_044317553.1 7 0 4 0 1 NA NA NA NA NA NA 22241 XM_029341390.2 75 227 106 453 106 Q91ZV7 1.04e-53 Plexin domain-containing protein 1 (Tumor endothelial marker 7) Mus musculus (Mouse) spinal cord development [GO:0021510] GO:0005737; GO:0005886; GO:0005923; GO:0021510; GO:0030425; GO:0043025; GO:0043235 22242 XM_044315253.1 80 20 1 34 10 Q96AY4 3.68e-116 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22243 XM_044315253.1 80 20 1 34 10 Q96AY4 1.73e-98 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22244 XM_044315253.1 80 20 1 34 10 Q96AY4 2.39e-89 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22245 XM_044315253.1 80 20 1 34 10 Q96AY4 2.97e-88 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22246 XM_044315253.1 80 20 1 34 10 Q96AY4 1.17e-87 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22247 XM_044315253.1 80 20 1 34 10 Q96AY4 3.58e-85 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22248 XM_029323897.2 184 241 11 110 177 NA NA NA NA NA NA 22249 XM_029335682.2 19 0 0 0 16 Q0KHQ5 1.74e-161 Serine/threonine-protein kinase Tao (EC 2.7.11.1) Drosophila melanogaster (Fruit fly) apoptotic process [GO:0006915]; central complex development [GO:0048036]; follicle cell of egg chamber development [GO:0030707]; intestinal stem cell homeostasis [GO:0036335]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; mushroom body development [GO:0016319]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of organ growth [GO:0046621]; negative regulation of synaptic assembly at neuromuscular junction [GO:0045886]; neuron projection morphogenesis [GO:0048812]; positive regulation of endocytosis [GO:0045807]; positive regulation of hippo signaling [GO:0035332]; protein phosphorylation [GO:0006468]; R8 cell fate commitment [GO:0007460]; regulation of MAPK cascade [GO:0043408]; response to cocaine [GO:0042220]; response to ethanol [GO:0045471]; response to nicotine [GO:0035094]; tissue homeostasis [GO:0001894] GO:0000165; GO:0001894; GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0005819; GO:0005874; GO:0005886; GO:0005938; GO:0006468; GO:0006915; GO:0007460; GO:0016020; GO:0016319; GO:0030424; GO:0030514; GO:0030707; GO:0035094; GO:0035332; GO:0035556; GO:0036335; GO:0042220; GO:0043204; GO:0043408; GO:0045178; GO:0045471; GO:0045807; GO:0045886; GO:0046621; GO:0048036; GO:0048812; GO:0106310 22250 XM_029335682.2 19 0 0 0 16 Q0KHQ5 6.85e-86 Serine/threonine-protein kinase Tao (EC 2.7.11.1) Drosophila melanogaster (Fruit fly) apoptotic process [GO:0006915]; central complex development [GO:0048036]; follicle cell of egg chamber development [GO:0030707]; intestinal stem cell homeostasis [GO:0036335]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; mushroom body development [GO:0016319]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of organ growth [GO:0046621]; negative regulation of synaptic assembly at neuromuscular junction [GO:0045886]; neuron projection morphogenesis [GO:0048812]; positive regulation of endocytosis [GO:0045807]; positive regulation of hippo signaling [GO:0035332]; protein phosphorylation [GO:0006468]; R8 cell fate commitment [GO:0007460]; regulation of MAPK cascade [GO:0043408]; response to cocaine [GO:0042220]; response to ethanol [GO:0045471]; response to nicotine [GO:0035094]; tissue homeostasis [GO:0001894] GO:0000165; GO:0001894; GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0005819; GO:0005874; GO:0005886; GO:0005938; GO:0006468; GO:0006915; GO:0007460; GO:0016020; GO:0016319; GO:0030424; GO:0030514; GO:0030707; GO:0035094; GO:0035332; GO:0035556; GO:0036335; GO:0042220; GO:0043204; GO:0043408; GO:0045178; GO:0045471; GO:0045807; GO:0045886; GO:0046621; GO:0048036; GO:0048812; GO:0106310 22251 XR_006392892.1 41 2 25 5 151 NA NA NA NA NA NA 22252 XR_003826454.2 14 54 15 36 21 NA NA NA NA NA NA 22253 XM_044308239.1 2152 1219 1362 2362 2802 Q8NFA0 0 Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.4.19.12) (Deubiquitinating enzyme 32) (Renal carcinoma antigen NY-REN-60) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32) Homo sapiens (Human) protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004843; GO:0005509; GO:0005794; GO:0005829; GO:0006511; GO:0016020; GO:0016579 22254 XM_044308239.1 2152 1219 1362 2362 2802 Q8NFA0 2.89e-94 Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.4.19.12) (Deubiquitinating enzyme 32) (Renal carcinoma antigen NY-REN-60) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32) Homo sapiens (Human) protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004843; GO:0005509; GO:0005794; GO:0005829; GO:0006511; GO:0016020; GO:0016579 22255 XM_044308239.1 2152 1219 1362 2362 2802 Q8NFA0 8.96e-28 Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.4.19.12) (Deubiquitinating enzyme 32) (Renal carcinoma antigen NY-REN-60) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32) Homo sapiens (Human) protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004843; GO:0005509; GO:0005794; GO:0005829; GO:0006511; GO:0016020; GO:0016579 22256 XM_044321557.1 30 7 12 10 21 NA NA NA NA NA NA 22257 XM_029325126.2 2238 2928 2525 2578 3222 Q9GKT2 1.31e-115 Fatty acid hydroxylase domain-containing protein 2 Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) lipid biosynthetic process [GO:0008610]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein phosphorylation [GO:0001934] GO:0001934; GO:0005506; GO:0005737; GO:0008610; GO:0016020; GO:0016491; GO:0045654 22258 XM_029326293.2 1 2 14 5 81 NA NA NA NA NA NA 22259 XR_006392614.1 73 33 21 13 46 NA NA NA NA NA NA 22260 XM_029355640.2 83 27 44 20 79 NA NA NA NA NA NA 22261 XM_044322159.1 993 689 553 601 598 NA NA NA NA NA NA 22262 XM_029333068.2 960 808 840 760 959 NA NA NA NA NA NA 22263 XM_029350677.2 945 1118 763 1259 1734 Q8QGW7 1.05e-22 Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog (LPS-induced TNF-alpha factor homolog) (Small integral membrane protein of lysosome/late endosome) Gallus gallus (Chicken) cytokine production [GO:0001816]; sexual reproduction [GO:0019953] GO:0000139; GO:0001816; GO:0003677; GO:0005125; GO:0005634; GO:0005765; GO:0008270; GO:0009898; GO:0019953; GO:0098559; GO:0098560; GO:0098574 22264 XR_006392779.1 141 107 0 359 345 NA NA NA NA NA NA 22265 XM_044321417.1 31 58 23 23 34 NA NA NA NA NA NA 22266 XM_029334851.2 32 32 91 13 43 P42674 2.72e-54 Blastula protease 10 (EC 3.4.24.-) Paracentrotus lividus (Common sea urchin) proteolysis [GO:0006508] GO:0004222; GO:0005615; GO:0005938; GO:0006508; GO:0008270; GO:0048471 22267 XM_044322079.1 0 0 84 0 0 B1AJZ9 1.5e-31 Forkhead-associated domain-containing protein 1 (FHA domain-containing protein 1) Homo sapiens (Human) NA NA 22268 XM_044322079.1 0 0 84 0 0 B1AJZ9 9.75e-29 Forkhead-associated domain-containing protein 1 (FHA domain-containing protein 1) Homo sapiens (Human) NA NA 22269 XM_044319722.1 0 2 8 10 0 NA NA NA NA NA NA 22270 XM_029336394.2 199 42 53 57 109 NA NA NA NA NA NA 22271 XM_029346870.2 2627 2437 2217 2520 2106 P23381 0 Tryptophan--tRNA ligase, cytoplasmic (EC 6.1.1.2) (Interferon-induced protein 53) (IFP53) (Tryptophanyl-tRNA synthetase) (TrpRS) (hWRS) [Cleaved into: T1-TrpRS; T2-TrpRS] Homo sapiens (Human) angiogenesis [GO:0001525]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of gene expression [GO:0010628]; positive regulation of protein-containing complex assembly [GO:0031334]; regulation of angiogenesis [GO:0045765]; translation [GO:0006412]; tryptophanyl-tRNA aminoacylation [GO:0006436] GO:0001525; GO:0004830; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006412; GO:0006436; GO:0006469; GO:0008285; GO:0010628; GO:0019210; GO:0019901; GO:0019904; GO:0031334; GO:0032991; GO:0042803; GO:0045765; GO:0070062 22272 XM_029324536.2 288 463 200 245 136 Q0II76 8.06e-55 Gamma-aminobutyric acid receptor subunit rho-2 (GABA(A) receptor subunit rho-2) (GABA(C) receptor) Bos taurus (Bovine) chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid signaling pathway [GO:0007214]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165]; visual perception [GO:0007601] GO:0004890; GO:0005231; GO:0005254; GO:0005886; GO:0007165; GO:0007214; GO:0007268; GO:0007601; GO:0030594; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:1902476; GO:1902711; GO:1904315 22273 XM_029348309.2 314 270 74 339 190 NA NA NA NA NA NA 22274 XM_044310266.1 44 22 48 0 110 NA NA NA NA NA NA 22275 XM_029340611.2 808 975 0 765 2 NA NA NA NA NA NA 22276 XM_029351345.2 1420 1403 1000 1577 1385 NA NA NA NA NA NA 22277 XM_044316235.1 0 0 9 3 74 Q9VBW3 8.67e-60 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 22278 XM_044324945.1 24 56 78 46 117 B7PRF6 8.25e-83 Acireductone dioxygenase (Acireductone dioxygenase (Fe(2+)-requiring)) (ARD') (Fe-ARD) (EC 1.13.11.54) (Acireductone dioxygenase (Ni(2+)-requiring)) (ARD) (Ni-ARD) (EC 1.13.11.53) Ixodes scapularis (Black-legged tick) (Deer tick) L-methionine salvage from methylthioadenosine [GO:0019509]; methionine metabolic process [GO:0006555] GO:0005506; GO:0005634; GO:0005737; GO:0006555; GO:0010308; GO:0010309; GO:0016151; GO:0019509 22279 XM_044328060.1 95 169 80 140 244 NA NA NA NA NA NA 22280 XM_029349430.2 6 4 0 34 33 NA NA NA NA NA NA 22281 XM_044308580.1 2149 1652 961 1646 527 Q16774 7.18e-69 Guanylate kinase (EC 2.7.4.8) (GMP kinase) (Guanylate kinase 1) Homo sapiens (Human) dGDP biosynthetic process [GO:0006185]; nucleobase-containing small molecule interconversion [GO:0015949]; phosphorylation [GO:0016310]; purine nucleotide metabolic process [GO:0006163]; xenobiotic metabolic process [GO:0006805] GO:0001917; GO:0004385; GO:0005524; GO:0005829; GO:0006163; GO:0006185; GO:0006805; GO:0015949; GO:0016310 22282 XM_029349871.2 63 28 0 5 0 Q6IRI9 4.46e-39 Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.-) (Dimethylaniline oxidase 2) (Pulmonary flavin-containing monooxygenase 2) (FMO 2) Rattus norvegicus (Rat) energy homeostasis [GO:0097009]; NADP metabolic process [GO:0006739]; NADPH oxidation [GO:0070995]; negative regulation of fatty acid oxidation [GO:0046322]; organic acid metabolic process [GO:0006082]; oxygen metabolic process [GO:0072592]; toxin metabolic process [GO:0009404]; xenobiotic metabolic process [GO:0006805] GO:0004497; GO:0004499; GO:0005789; GO:0006082; GO:0006739; GO:0006805; GO:0009404; GO:0016020; GO:0046322; GO:0047822; GO:0050660; GO:0050661; GO:0070995; GO:0072592; GO:0097009 22283 XM_044323844.1 4762 3575 2926 5698 4557 O57683 0 Splicing factor 3B subunit 1 (146 kDa nuclear protein) (Pre-mRNA-splicing factor SF3b 155 kDa subunit) (SF3b155) (Spliceosome-associated protein 155) (SAP 155) Xenopus laevis (African clawed frog) spliceosomal complex assembly [GO:0000245] GO:0000245; GO:0003729; GO:0005634; GO:0005681 22284 XM_029355296.2 64 67 7 25 8 P21580 7.14e-66 Tumor necrosis factor alpha-induced protein 3 (TNF alpha-induced protein 3) (EC 2.3.2.-) (EC 3.4.19.12) (OTU domain-containing protein 7C) (Putative DNA-binding protein A20) (Zinc finger protein A20) [Cleaved into: A20p50; A20p37] Homo sapiens (Human) apoptotic process [GO:0006915]; B-1 B cell homeostasis [GO:0001922]; cell migration [GO:0016477]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cytoskeleton organization [GO:0007010]; establishment of protein localization to vacuole [GO:0072666]; inflammatory response [GO:0006954]; negative regulation of B cell activation [GO:0050869]; negative regulation of bone resorption [GO:0045779]; negative regulation of CD40 signaling pathway [GO:2000349]; negative regulation of chronic inflammatory response [GO:0002677]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [GO:0070429]; negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070433]; negative regulation of osteoclast proliferation [GO:0090291]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of toll-like receptor 3 signaling pathway [GO:0034140]; negative regulation of toll-like receptor 4 signaling pathway [GO:0034144]; negative regulation of toll-like receptor 5 signaling pathway [GO:0034148]; negative regulation of tumor necrosis factor production [GO:0032720]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; positive regulation of hepatocyte proliferation [GO:2000347]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of Wnt signaling pathway [GO:0030177]; protein deubiquitination [GO:0016579]; protein deubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0071947]; protein K11-linked deubiquitination [GO:0035871]; protein K29-linked deubiquitination [GO:0035523]; protein K33-linked deubiquitination [GO:1990168]; protein K48-linked deubiquitination [GO:0071108]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked deubiquitination [GO:0070536]; regulation of defense response to virus by host [GO:0050691]; regulation of germinal center formation [GO:0002634]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; regulation of vascular wound healing [GO:0061043]; response to molecule of bacterial origin [GO:0002237]; response to muramyl dipeptide [GO:0032495]; tolerance induction to lipopolysaccharide [GO:0072573] GO:0001922; GO:0002020; GO:0002237; GO:0002634; GO:0002677; GO:0003677; GO:0004842; GO:0004843; GO:0005634; GO:0005737; GO:0005764; GO:0005829; GO:0006915; GO:0006954; GO:0007010; GO:0008022; GO:0008270; GO:0010803; GO:0016477; GO:0016579; GO:0019900; GO:0030177; GO:0031397; GO:0032088; GO:0032495; GO:0032691; GO:0032703; GO:0032715; GO:0032720; GO:0034136; GO:0034140; GO:0034144; GO:0034148; GO:0035523; GO:0035871; GO:0042802; GO:0043124; GO:0043130; GO:0043621; GO:0045732; GO:0045736; GO:0045779; GO:0045824; GO:0048662; GO:0050691; GO:0050728; GO:0050869; GO:0061043; GO:0061578; GO:0070062; GO:0070301; GO:0070423; GO:0070429; GO:0070433; GO:0070530; GO:0070536; GO:0070936; GO:0071108; GO:0071222; GO:0071947; GO:0072573; GO:0072666; GO:0090291; GO:1902042; GO:1990168; GO:2000347; GO:2000349; GO:2000352 22285 XM_044321064.1 189 112 20 305 345 NA NA NA NA NA NA 22286 XM_029354540.2 870 562 398 545 475 NA NA NA NA NA NA 22287 XM_029358527.2 5 19 14 19 0 NA NA NA NA NA NA 22288 XM_029348407.2 3822 3328 1885 3890 4316 Q90828 5.15e-147 Cytoplasmic dynein 1 light intermediate chain 1 (Dynein light chain A) (DLC-A) (Dynein light intermediate chain 1, cytosolic) (LIC57/59) Gallus gallus (Chicken) microtubule cytoskeleton organization [GO:0000226]; microtubule-based movement [GO:0007018] GO:0000226; GO:0005524; GO:0005737; GO:0005868; GO:0005874; GO:0007018; GO:0045504 22289 XR_006392709.1 195 87 185 162 303 NA NA NA NA NA NA 22290 XM_029324353.2 208 93 0 58 28 NA NA NA NA NA NA 22291 XM_044317058.1 53 0 17 0 70 NA NA NA NA NA NA 22292 XM_044327443.1 481 657 418 439 578 NA NA NA NA NA NA 22293 XM_044310869.1 7 131 1 232 0 NA NA NA NA NA NA 22294 XM_044309981.1 13 22 21 22 7 O00602 6.32e-79 Ficolin-1 (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin-alpha) (M-ficolin) Homo sapiens (Human) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation, lectin pathway [GO:0001867]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of viral entry into host cell [GO:0046597]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of opsonization [GO:1903028]; protein localization to cell surface [GO:0034394]; proteolysis [GO:0006508]; recognition of apoptotic cell [GO:0043654] GO:0001664; GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005576; GO:0005581; GO:0005615; GO:0006508; GO:0007186; GO:0009897; GO:0030246; GO:0031232; GO:0032757; GO:0033691; GO:0034394; GO:0034774; GO:0038187; GO:0043654; GO:0046597; GO:0046872; GO:0062023; GO:0097367; GO:1903028; GO:1904813; GO:1905370 22295 XM_029325590.2 416 656 532 839 947 Q6AYU1 8.21e-116 Mortality factor 4-like protein 1 (MORF-related gene 15 protein) (Transcription factor-like protein MRG15) Rattus norvegicus (Rat) cell population proliferation [GO:0008283]; chromatin organization [GO:0006325]; double-strand break repair via homologous recombination [GO:0000724]; fibroblast proliferation [GO:0048144]; histone acetylation [GO:0016573]; histone deacetylation [GO:0016575]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; regulation of cell cycle [GO:0051726] GO:0000123; GO:0000724; GO:0000786; GO:0003682; GO:0006325; GO:0008283; GO:0016573; GO:0016575; GO:0016580; GO:0035267; GO:0043967; GO:0043968; GO:0045893; GO:0047485; GO:0048144; GO:0051726; GO:1905168 22296 XM_044308978.1 660 154 120 327 428 NA NA NA NA NA NA 22297 XR_006393028.1 1 6 0 0 0 NA NA NA NA NA NA 22298 XR_006392022.1 8 6 17 19 9 Q96DM1 5.49e-36 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 22299 XM_044328201.1 1105 711 324 465 415 Q8C428 2.28e-81 Transmembrane channel-like protein 7 Mus musculus (Mouse) NA GO:0005886; GO:0008381 22300 XM_044328521.1 0 0 55 0 0 Q9NVV5 3.24e-40 Androgen-induced gene 1 protein (AIG-1) (Fatty acid esters of hydroxy fatty acids hydrolase AIG1) (FAHFA hydrolase AIG1) (EC 3.1.-.-) Homo sapiens (Human) long-chain fatty acid catabolic process [GO:0042758] GO:0005886; GO:0012505; GO:0016020; GO:0016787; GO:0042758 22301 XM_029336785.2 461 395 260 273 357 NA NA NA NA NA NA 22302 XR_003825178.2 17 0 3 0 0 NA NA NA NA NA NA 22303 XM_044309070.1 4 34 12 19 38 D4DCG0 4.37e-24 Probable dipeptidyl-aminopeptidase B (DPAP B) (EC 3.4.14.5) Trichophyton verrucosum (strain HKI 0517) proteolysis [GO:0006508] GO:0004177; GO:0004252; GO:0005774; GO:0006508; GO:0008239 22304 XM_029333084.2 7 5 20 14 44 Q64604 1.64e-25 Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) (Leukocyte common antigen related) (LAR) Rattus norvegicus (Rat) cell migration [GO:0016477]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell projection organization [GO:0031345]; negative regulation of cytokine-mediated signaling pathway [GO:0001960]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of neurotrophin TRK receptor signaling pathway [GO:0051387]; negative regulation of receptor binding [GO:1900121]; nervous system development [GO:0007399]; neuron projection regeneration [GO:0031102]; peptidyl-tyrosine dephosphorylation [GO:0035335]; positive regulation of apoptotic process [GO:0043065]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of neuron apoptotic process [GO:0043525]; protein dephosphorylation [GO:0006470]; regulation of axon regeneration [GO:0048679]; regulation of neuron projection development [GO:0010975]; regulation of postsynapse organization [GO:0099175]; regulation of synapse structure or activity [GO:0050803]; synaptic membrane adhesion [GO:0099560] GO:0001960; GO:0004725; GO:0005001; GO:0005158; GO:0005768; GO:0005886; GO:0006470; GO:0007156; GO:0007399; GO:0008201; GO:0008285; GO:0010975; GO:0016020; GO:0016477; GO:0030426; GO:0030971; GO:0031102; GO:0031345; GO:0035335; GO:0035373; GO:0042059; GO:0042301; GO:0043005; GO:0043025; GO:0043065; GO:0043231; GO:0043525; GO:0044877; GO:0046627; GO:0048679; GO:0050775; GO:0050803; GO:0050839; GO:0051387; GO:0060076; GO:0098839; GO:0099175; GO:0099560; GO:1900121 22305 XM_029333084.2 7 5 20 14 44 Q64604 1.49e-23 Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) (Leukocyte common antigen related) (LAR) Rattus norvegicus (Rat) cell migration [GO:0016477]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell projection organization [GO:0031345]; negative regulation of cytokine-mediated signaling pathway [GO:0001960]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of neurotrophin TRK receptor signaling pathway [GO:0051387]; negative regulation of receptor binding [GO:1900121]; nervous system development [GO:0007399]; neuron projection regeneration [GO:0031102]; peptidyl-tyrosine dephosphorylation [GO:0035335]; positive regulation of apoptotic process [GO:0043065]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of neuron apoptotic process [GO:0043525]; protein dephosphorylation [GO:0006470]; regulation of axon regeneration [GO:0048679]; regulation of neuron projection development [GO:0010975]; regulation of postsynapse organization [GO:0099175]; regulation of synapse structure or activity [GO:0050803]; synaptic membrane adhesion [GO:0099560] GO:0001960; GO:0004725; GO:0005001; GO:0005158; GO:0005768; GO:0005886; GO:0006470; GO:0007156; GO:0007399; GO:0008201; GO:0008285; GO:0010975; GO:0016020; GO:0016477; GO:0030426; GO:0030971; GO:0031102; GO:0031345; GO:0035335; GO:0035373; GO:0042059; GO:0042301; GO:0043005; GO:0043025; GO:0043065; GO:0043231; GO:0043525; GO:0044877; GO:0046627; GO:0048679; GO:0050775; GO:0050803; GO:0050839; GO:0051387; GO:0060076; GO:0098839; GO:0099175; GO:0099560; GO:1900121 22306 XM_029340518.2 1121 879 592 1220 946 Q568Z6 4.34e-62 IST1 homolog (Charged multivesicular body protein 8) (CHMP8) Rattus norvegicus (Rat) abscission [GO:0009838]; cell division [GO:0051301]; collateral sprouting [GO:0048668]; cytoskeleton-dependent cytokinesis [GO:0061640]; establishment of protein localization [GO:0045184]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of proteolysis [GO:0045862]; protein localization [GO:0008104]; protein transport [GO:0015031]; viral capsid secondary envelopment [GO:0046745]; viral release from host cell [GO:0019076] GO:0000785; GO:0005635; GO:0005793; GO:0005813; GO:0005829; GO:0008104; GO:0009838; GO:0015031; GO:0019076; GO:0019904; GO:0030496; GO:0031410; GO:0044877; GO:0045184; GO:0045862; GO:0046745; GO:0048668; GO:0048672; GO:0051301; GO:0061640; GO:0090541; GO:0090543 22307 XM_029356655.2 6 3 4 11 4 NA NA NA NA NA NA 22308 XM_044317521.1 60 22 17 16 32 Q8BHB0 1.14e-29 Nucleotide-binding oligomerization domain-containing protein 1 (Caspase recruitment domain-containing protein 4) Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cellular response to muramyl dipeptide [GO:0071225]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; ERK1 and ERK2 cascade [GO:0070371]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of cell death [GO:0010942]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of xenophagy [GO:1904417]; regulation of apoptotic process [GO:0042981]; stress-activated MAPK cascade [GO:0051403]; xenophagy [GO:0098792] GO:0002221; GO:0002606; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006915; GO:0006919; GO:0007249; GO:0007254; GO:0010942; GO:0016045; GO:0016323; GO:0016324; GO:0032731; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0035556; GO:0038187; GO:0042742; GO:0042802; GO:0042803; GO:0042981; GO:0043123; GO:0043280; GO:0044877; GO:0045087; GO:0045335; GO:0046330; GO:0050700; GO:0050830; GO:0051000; GO:0051092; GO:0051403; GO:0060907; GO:0070371; GO:0070374; GO:0071225; GO:0098792; GO:1901224; GO:1904417 22309 XM_044320320.1 337 294 358 487 568 Q32LE3 4.5e-96 Centrin-1 Bos taurus (Bovine) cell division [GO:0051301]; centriole replication [GO:0007099]; mitotic cell cycle [GO:0000278]; nucleotide-excision repair [GO:0006289] GO:0000278; GO:0000922; GO:0005509; GO:0005737; GO:0005813; GO:0005814; GO:0006289; GO:0007099; GO:0051301 22310 XM_029350562.2 182 327 244 212 246 NA NA NA NA NA NA 22311 XM_044309527.1 0 0 59 0 0 Q6NY73 1.08e-25 Galectin-3-binding protein B (Lectin galactoside-binding soluble 3-binding protein B) Danio rerio (Zebrafish) (Brachydanio rerio) cell adhesion [GO:0007155] GO:0005044; GO:0005576; GO:0007155; GO:0016020 22312 XR_006397337.1 0 0 0 0 8 NA NA NA NA NA NA 22313 XM_044320197.1 26 0 0 0 0 Q9LQV2 5.98e-50 RNA-dependent RNA polymerase 1 (AtRDRP1) (EC 2.7.7.48) (RNA-directed RNA polymerase 1) Arabidopsis thaliana (Mouse-ear cress) defense response [GO:0006952]; positive regulation of post-transcriptional gene silencing [GO:0060148]; response to salicylic acid [GO:0009751]; response to virus [GO:0009615]; siRNA processing [GO:0030422]; wax biosynthetic process [GO:0010025] GO:0003723; GO:0003968; GO:0006952; GO:0009615; GO:0009751; GO:0010025; GO:0030422; GO:0031380; GO:0060148 22314 XR_006392915.1 41 2 25 5 151 NA NA NA NA NA NA 22315 XM_029334704.2 398 201 94 319 376 Q9FGB1 1.37e-28 NA NA NA NA 22316 XM_029353094.2 501 466 278 480 136 Q63ZI0 4.59e-80 Potassium channel subfamily K member 9 Xenopus laevis (African clawed frog) NA GO:0005267; GO:0005886 22317 XM_044318983.1 128 125 84 0 17 P70196 7.84e-81 TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6) Mus musculus (Mouse) activation of NF-kappaB-inducing kinase activity [GO:0007250]; activation of protein kinase activity [GO:0032147]; animal organ morphogenesis [GO:0009887]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; bone remodeling [GO:0046849]; bone resorption [GO:0045453]; cell development [GO:0048468]; cellular response to cytokine stimulus [GO:0071345]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-17-mediated signaling pathway [GO:0097400]; JNK cascade [GO:0007254]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin production [GO:0002637]; response to interleukin-1 [GO:0070555]; signal transduction [GO:0007165]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000122; GO:0000209; GO:0001503; GO:0001701; GO:0001843; GO:0002637; GO:0002726; GO:0004842; GO:0005164; GO:0005634; GO:0005737; GO:0005811; GO:0005829; GO:0005886; GO:0005938; GO:0006955; GO:0006974; GO:0007165; GO:0007249; GO:0007250; GO:0007254; GO:0008270; GO:0009887; GO:0009898; GO:0016567; GO:0019221; GO:0019886; GO:0019901; GO:0030316; GO:0031435; GO:0031624; GO:0031625; GO:0031663; GO:0031666; GO:0031996; GO:0032147; GO:0032735; GO:0032743; GO:0032755; GO:0032813; GO:0032991; GO:0033209; GO:0035631; GO:0042088; GO:0042102; GO:0042475; GO:0042802; GO:0042826; GO:0042981; GO:0043011; GO:0043122; GO:0043123; GO:0043422; GO:0043507; GO:0045453; GO:0045672; GO:0045892; GO:0045944; GO:0046330; GO:0046849; GO:0047485; GO:0048468; GO:0048471; GO:0048661; GO:0050852; GO:0051091; GO:0051092; GO:0051865; GO:0061630; GO:0070498; GO:0070534; GO:0070555; GO:0071222; GO:0071345; GO:0097400; GO:1901224; GO:1904996; GO:2000679 22318 XR_006394610.1 0 2 0 10 0 NA NA NA NA NA NA 22319 XR_006392411.1 72 170 71 14 34 NA NA NA NA NA NA 22320 XM_044327886.1 24 17 19 1 57 NA NA NA NA NA NA 22321 XM_029348135.2 79 14 17 18 54 P49338 1.46e-117 Protein Wnt-4 (XWnt-4) Xenopus laevis (African clawed frog) embryonic pattern specification [GO:0009880]; glomus development [GO:0072013]; nephrostome development [GO:0039018]; pronephric nephron tubule development [GO:0039020]; Wnt signaling pathway [GO:0016055] GO:0005102; GO:0005576; GO:0009880; GO:0016055; GO:0039018; GO:0039020; GO:0072013 22322 XM_029328420.2 0 0 14 0 10 Q8VE38 2.79e-60 Oxidoreductase NAD-binding domain-containing protein 1 (EC 1.-.-.-) Mus musculus (Mouse) NA GO:0005739; GO:0016491 22323 XR_006395752.1 149 69 86 42 257 NA NA NA NA NA NA 22324 XM_029358304.2 6 0 154 0 0 Q9QYS2 0 Metabotropic glutamate receptor 3 (mGluR3) Mus musculus (Mouse) G protein-coupled glutamate receptor signaling pathway [GO:0007216]; gene expression [GO:0010467]; modulation of chemical synaptic transmission [GO:0050804]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; regulation of sensory perception of pain [GO:0051930]; regulation of synaptic transmission, glutamatergic [GO:0051966]; sensory perception of pain [GO:0019233]; synaptic transmission, glutamatergic [GO:0035249] GO:0001640; GO:0001641; GO:0005246; GO:0005886; GO:0007216; GO:0010467; GO:0014069; GO:0019233; GO:0030424; GO:0035249; GO:0042734; GO:0043005; GO:0043197; GO:0045211; GO:0048786; GO:0050804; GO:0051930; GO:0051966; GO:0097110; GO:0097449; GO:0098978; GO:0099170 22325 XR_006393651.1 51 444 732 274 193 NA NA NA NA NA NA 22326 XM_029344504.2 239 214 50 129 147 Q3SZ85 1.78e-31 Putative peptidyl-tRNA hydrolase PTRHD1 (EC 3.1.1.29) (Peptidyl-tRNA hydrolase domain-containing protein 1) Bos taurus (Bovine) NA GO:0004045 22327 XR_006396355.1 153 58 97 92 179 Q8JIR0 2.57e-53 Polycomb complex protein BMI-1-A (Polycomb group RING finger protein 4-A) Danio rerio (Zebrafish) (Brachydanio rerio) cerebellum development [GO:0021549]; hematopoietic stem cell migration [GO:0035701]; histone H2A-K119 monoubiquitination [GO:0036353]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of transcription by RNA polymerase II [GO:0000122]; primitive hemopoiesis [GO:0060215] GO:0000122; GO:0021549; GO:0031519; GO:0035102; GO:0035701; GO:0036353; GO:0045814; GO:0046872; GO:0060215; GO:1990841 22328 XM_029358118.2 243 217 149 196 218 Q8C0L6 9.47e-75 Peroxisomal N(1)-acetyl-spermine/spermidine oxidase (EC 1.5.3.13) (Polyamine oxidase) Mus musculus (Mouse) polyamine catabolic process [GO:0006598]; positive regulation of spermidine biosynthetic process [GO:1901307]; putrescine biosynthetic process [GO:0009446]; putrescine catabolic process [GO:0009447]; spermidine catabolic process [GO:0046203]; spermine catabolic process [GO:0046208] GO:0005782; GO:0006598; GO:0009446; GO:0009447; GO:0016491; GO:0046203; GO:0046208; GO:0046592; GO:0052899; GO:0052901; GO:0052902; GO:0052903; GO:0052904; GO:1901307 22329 XR_006395184.1 226 237 312 395 688 NA NA NA NA NA NA 22330 XM_029329355.2 721 849 607 740 593 P22739 1.74e-98 Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (xSHA2) Xenopus laevis (African clawed frog) neuronal action potential [GO:0019228]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005251; GO:0005886; GO:0008076; GO:0019228; GO:0034765; GO:0044224; GO:0051260; GO:0071805 22331 XM_044325430.1 413 234 15 23 30 NA NA NA NA NA NA 22332 XM_029323731.2 632 420 327 393 749 Q8R344 4.88e-34 Coiled-coil domain-containing protein 12 Mus musculus (Mouse) NA GO:0005684; GO:0071014 22333 XR_006393985.1 2862 2202 1187 2016 2567 NA NA NA NA NA NA 22334 XR_006395355.1 4 0 2 9 3 NA NA NA NA NA NA 22335 XM_029336315.2 11685 10295 5259 8648 3781 Q9Y603 7.75e-22 Transcription factor ETV7 (ETS translocation variant 7) (ETS-related protein Tel2) (Tel-related Ets factor) (Transcription factor Tel-2) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell differentiation [GO:0030154]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366] GO:0000122; GO:0000785; GO:0000977; GO:0000981; GO:0001227; GO:0005634; GO:0005654; GO:0006357; GO:0006366; GO:0009887; GO:0030154; GO:1990837 22336 XM_029336553.2 8458 10803 5891 8169 6485 Q6P2Z0 7.28e-174 eIF5-mimic protein 2 (Basic leucine zipper and W2 domain-containing protein 1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) regulation of translational initiation [GO:0006446] GO:0006446 22337 XM_044316238.1 83 16 104 33 496 NA NA NA NA NA NA 22338 XM_029333754.1 96 75 108 145 268 NA NA NA NA NA NA 22339 XM_044306760.1 1628 871 920 1349 1289 Q5ND34 5.96e-113 WD repeat-containing protein 81 Mus musculus (Mouse) aggrephagy [GO:0035973]; early endosome to late endosome transport [GO:0045022]; mitochondrion organization [GO:0007005]; protein stabilization [GO:0050821]; regulation of phosphatidylinositol 3-kinase activity [GO:0043551]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000421; GO:0005739; GO:0005765; GO:0005829; GO:0006511; GO:0007005; GO:0031313; GO:0031901; GO:0031902; GO:0035014; GO:0035973; GO:0043551; GO:0045022; GO:0050821; GO:0070530 22340 XM_044306760.1 1628 871 920 1349 1289 Q5ND34 5.74e-58 WD repeat-containing protein 81 Mus musculus (Mouse) aggrephagy [GO:0035973]; early endosome to late endosome transport [GO:0045022]; mitochondrion organization [GO:0007005]; protein stabilization [GO:0050821]; regulation of phosphatidylinositol 3-kinase activity [GO:0043551]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000421; GO:0005739; GO:0005765; GO:0005829; GO:0006511; GO:0007005; GO:0031313; GO:0031901; GO:0031902; GO:0035014; GO:0035973; GO:0043551; GO:0045022; GO:0050821; GO:0070530 22341 XM_044311775.1 11 21 10 37 13 NA NA NA NA NA NA 22342 XM_029339431.2 360 236 26 266 424 Q7T163 0 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 22343 XM_029339431.2 360 236 26 266 424 Q7T163 4.07e-42 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 22344 XM_029339431.2 360 236 26 266 424 Q7T163 6.63e-38 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 22345 XM_029339431.2 360 236 26 266 424 Q7T163 6.54e-23 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 22346 XM_029346908.2 22 0 19 6 29 NA NA NA NA NA NA 22347 XM_029335532.2 2761 937 1384 2062 2948 NA NA NA NA NA NA 22348 XR_006397144.1 56 14 23 49 81 NA NA NA NA NA NA 22349 XR_006395990.1 534 222 618 1089 826 NA NA NA NA NA NA 22350 XR_003828353.2 38 32 67 119 102 NA NA NA NA NA NA 22351 XM_044310818.1 58 2 0 139 61 NA NA NA NA NA NA 22352 XM_029346573.2 382 280 53 325 227 NA NA NA NA NA NA 22353 XM_044327094.1 14 0 21 11 49 NA NA NA NA NA NA 22354 XM_044326420.1 633 248 359 519 552 Q9BXT6 0 RNA helicase Mov10l1 (EC 3.6.4.13) (Moloney leukemia virus 10-like protein 1) (MOV10-like protein 1) Homo sapiens (Human) DNA methylation involved in gamete generation [GO:0043046]; germ cell development [GO:0007281]; male meiosis I [GO:0007141]; piRNA processing [GO:0034587]; RNA-mediated post-transcriptional gene silencing [GO:0035194]; spermatogenesis [GO:0007283] GO:0000287; GO:0003723; GO:0003724; GO:0005524; GO:0005829; GO:0007141; GO:0007281; GO:0007283; GO:0016887; GO:0034587; GO:0035194; GO:0043046; GO:0043186; GO:0071546 22355 XR_006394137.1 15 0 29 0 93 NA NA NA NA NA NA 22356 XM_029354745.2 0 0 0 0 28 NA NA NA NA NA NA 22357 XM_044323237.1 7 0 0 0 0 NA NA NA NA NA NA 22358 XM_044315565.1 29 8 3 10 16 Q9H5F2 5.73e-25 Uncharacterized protein CFAP68 (cilia and flagella associated protein 68) Homo sapiens (Human) NA GO:0005654 22359 XM_044320478.1 38 3 21 3 49 NA NA NA NA NA NA 22360 XM_029350223.2 111 129 36 80 102 Q9R0Z9 6.08e-159 Rho GTPase-activating protein 7 (Deleted in liver cancer 1 protein homolog) (DLC-1) (Rho-type GTPase-activating protein 7) (START domain-containing protein 12) (StARD12) (StAR-related lipid transfer protein 12) Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of phospholipase C activity [GO:0007202]; apoptotic process [GO:0006915]; cytoskeleton organization [GO:0007010]; focal adhesion assembly [GO:0048041]; forebrain development [GO:0030900]; heart morphogenesis [GO:0003007]; hindbrain morphogenesis [GO:0021575]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of stress fiber assembly [GO:0051497]; neural tube closure [GO:0001843]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; regulation of Rho protein signal transduction [GO:0035023]; signal transduction [GO:0007165] GO:0001725; GO:0001843; GO:0003007; GO:0005096; GO:0005634; GO:0005737; GO:0005829; GO:0005884; GO:0005901; GO:0005925; GO:0006915; GO:0006919; GO:0007010; GO:0007165; GO:0007202; GO:0008285; GO:0008289; GO:0008360; GO:0017166; GO:0021575; GO:0030036; GO:0030336; GO:0030864; GO:0030900; GO:0032587; GO:0032956; GO:0035023; GO:0035024; GO:0035307; GO:0042169; GO:0043274; GO:0045121; GO:0048041; GO:0051497; GO:0051895; GO:1900119 22361 XM_029350223.2 111 129 36 80 102 Q9R0Z9 1.18e-23 Rho GTPase-activating protein 7 (Deleted in liver cancer 1 protein homolog) (DLC-1) (Rho-type GTPase-activating protein 7) (START domain-containing protein 12) (StARD12) (StAR-related lipid transfer protein 12) Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of phospholipase C activity [GO:0007202]; apoptotic process [GO:0006915]; cytoskeleton organization [GO:0007010]; focal adhesion assembly [GO:0048041]; forebrain development [GO:0030900]; heart morphogenesis [GO:0003007]; hindbrain morphogenesis [GO:0021575]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of stress fiber assembly [GO:0051497]; neural tube closure [GO:0001843]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; regulation of Rho protein signal transduction [GO:0035023]; signal transduction [GO:0007165] GO:0001725; GO:0001843; GO:0003007; GO:0005096; GO:0005634; GO:0005737; GO:0005829; GO:0005884; GO:0005901; GO:0005925; GO:0006915; GO:0006919; GO:0007010; GO:0007165; GO:0007202; GO:0008285; GO:0008289; GO:0008360; GO:0017166; GO:0021575; GO:0030036; GO:0030336; GO:0030864; GO:0030900; GO:0032587; GO:0032956; GO:0035023; GO:0035024; GO:0035307; GO:0042169; GO:0043274; GO:0045121; GO:0048041; GO:0051497; GO:0051895; GO:1900119 22362 XM_044316641.1 0 7 0 0 0 NA NA NA NA NA NA 22363 XM_029355356.2 1890 1350 546 1424 1031 P78364 6.87e-38 Polyhomeotic-like protein 1 (hPH1) (Early development regulatory protein 1) Homo sapiens (Human) histone ubiquitination [GO:0016574]; negative regulation of DNA-templated transcription [GO:0045892] GO:0003677; GO:0003682; GO:0005634; GO:0005654; GO:0008270; GO:0016574; GO:0031519; GO:0035102; GO:0042393; GO:0045892 22364 XM_044308148.1 1078 1559 806 851 558 Q8IZQ5 2.75e-26 Selenoprotein H (SelH) Homo sapiens (Human) NA GO:0003723; GO:0005794 22365 XM_029329166.2 57 87 52 78 99 NA NA NA NA NA NA 22366 XM_029337838.2 21 27 41 70 15 Q8BLA8 1.71e-112 Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Wasabi receptor) Mus musculus (Mouse) calcium ion transmembrane import into cytosol [GO:0097553]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cell surface receptor signaling pathway [GO:0007166]; cellular calcium ion homeostasis [GO:0006874]; cellular response to carbon dioxide [GO:0071244]; cellular response to cold [GO:0070417]; cellular response to heat [GO:0034605]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to organic substance [GO:0071310]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; positive regulation of anion transport [GO:1903793]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of sensory perception of pain [GO:1904058]; protein homotetramerization [GO:0051289]; regulation of blood circulation [GO:1903522]; regulation of neuronal action potential [GO:0098908]; response to cold [GO:0009409]; response to hydrogen peroxide [GO:0042542]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; sensory perception of pain [GO:0019233]; thermoception [GO:0050955]; urinary bladder smooth muscle contraction [GO:0014832] GO:0005216; GO:0005245; GO:0005262; GO:0005886; GO:0006816; GO:0006874; GO:0007166; GO:0009409; GO:0009410; GO:0010033; GO:0014070; GO:0014832; GO:0015267; GO:0015278; GO:0016020; GO:0016324; GO:0019233; GO:0030424; GO:0032421; GO:0034605; GO:0035774; GO:0042542; GO:0042802; GO:0048265; GO:0050955; GO:0050966; GO:0050968; GO:0050974; GO:0051289; GO:0070301; GO:0070417; GO:0070588; GO:0071244; GO:0071310; GO:0097553; GO:0097604; GO:0098908; GO:1903522; GO:1903793; GO:1904058; GO:1990760 22367 XM_044320409.1 107 138 40 97 68 NA NA NA NA NA NA 22368 XM_044311051.1 263 30 72 256 101 P16157 2.49e-71 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 22369 XM_044311051.1 263 30 72 256 101 P16157 3.31e-65 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 22370 XM_044311051.1 263 30 72 256 101 P16157 7.79e-53 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 22371 XM_044308009.1 14 23 5 0 6 NA NA NA NA NA NA 22372 XM_044313073.1 8 0 31 49 83 NA NA NA NA NA NA 22373 XR_006391942.1 0 0 0 0 23 NA NA NA NA NA NA 22374 XM_044306806.1 603 129 485 564 1886 NA NA NA NA NA NA 22375 XR_006393670.1 0 0 0 6 0 NA NA NA NA NA NA 22376 XM_044311324.1 26 30 32 91 49 NA NA NA NA NA NA 22377 XM_044318989.1 49 40 45 26 11 NA NA NA NA NA NA 22378 XM_029356244.2 170 58 46 51 208 Q9JIM4 2.44e-49 Dual specificity protein phosphatase 12 (EC 3.1.3.16) (EC 3.1.3.48) (Glucokinase-associated dual specificity phosphatase) (GKAP) Rattus norvegicus (Rat) dephosphorylation [GO:0016311]; positive regulation of glucokinase activity [GO:0033133]; protein dephosphorylation [GO:0006470] GO:0004721; GO:0004725; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006470; GO:0008138; GO:0008270; GO:0016311; GO:0016791; GO:0017018; GO:0019900; GO:0033133 22379 XM_044314826.1 6 0 26 10 0 NA NA NA NA NA NA 22380 XM_029338445.2 353 183 203 324 804 Q8BIA4 5.45e-93 F-box/WD repeat-containing protein 8 (F-box and WD-40 domain-containing protein 8) Mus musculus (Mouse) cell population proliferation [GO:0008283]; Golgi organization [GO:0007030]; labyrinthine layer blood vessel development [GO:0060716]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of transcription factor catabolic process [GO:1901485]; protein ubiquitination [GO:0016567]; spongiotrophoblast layer development [GO:0060712]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004842; GO:0005794; GO:0005829; GO:0006511; GO:0007030; GO:0008283; GO:0016567; GO:0019005; GO:0031467; GO:0048471; GO:0050775; GO:0060712; GO:0060716; GO:1901485; GO:1990393 22381 XR_006394117.1 9 0 3 1 3 NA NA NA NA NA NA 22382 XM_029338453.2 238 202 215 126 362 Q1JQC1 1.62e-41 Major facilitator superfamily domain-containing protein 1 Bos taurus (Bovine) protein localization to lysosome [GO:0061462]; protein stabilization [GO:0050821] GO:0005764; GO:0005765; GO:0022857; GO:0042803; GO:0050821; GO:0061462 22383 XM_044313893.1 4 0 1 0 17 P61752 5.4e-28 Histamine H2 receptor (H2R) (HH2R) (Gastric receptor I) Pongo pygmaeus (Bornean orangutan) gastric acid secretion [GO:0001696]; positive regulation of vasoconstriction [GO:0045907] GO:0001696; GO:0004969; GO:0005886; GO:0045907 22384 XM_044315268.1 6 3 0 8 2 NA NA NA NA NA NA 22385 XM_044309864.1 0 6 0 0 0 NA NA NA NA NA NA 22386 XM_044311542.1 337 0 263 28 32 Q80W99 2e-59 Cation channel sperm-associated protein 3 (CatSper3) Mus musculus (Mouse) establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; regulation of ion transmembrane transport [GO:0034765]; sodium ion transport [GO:0006814]; sperm capacitation [GO:0048240] GO:0001669; GO:0005245; GO:0005783; GO:0006814; GO:0030317; GO:0031514; GO:0034765; GO:0036128; GO:0048240; GO:0051649 22387 XM_044317927.1 1252 748 734 1006 1065 B7W114 0 Cephalotoxin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 22388 XM_044317173.1 436 0 0 0 0 NA NA NA NA NA NA 22389 XM_029326052.2 124 93 151 111 245 P47739 2.32e-163 Aldehyde dehydrogenase, dimeric NADP-preferring (EC 1.2.1.5) (Aldehyde dehydrogenase 4) (Aldehyde dehydrogenase family 3 member A1) (Dioxin-inducible aldehyde dehydrogenase 3) Mus musculus (Mouse) cellular aldehyde metabolic process [GO:0006081]; lipid metabolic process [GO:0006629]; positive regulation of cell population proliferation [GO:0008284]; response to cAMP [GO:0051591]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to organic cyclic compound [GO:0014070]; response to xenobiotic stimulus [GO:0009410] GO:0001666; GO:0004028; GO:0004029; GO:0005737; GO:0005783; GO:0005829; GO:0005886; GO:0006081; GO:0006629; GO:0008106; GO:0008284; GO:0009410; GO:0014070; GO:0016020; GO:0016620; GO:0018479; GO:0051384; GO:0051591 22390 XM_044317772.1 1801 1623 937 1088 721 Q7ZVT5 1.85e-48 Protein rogdi homolog Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005635; GO:0008021; GO:0030424; GO:0030425; GO:0043204; GO:0043291 22391 XM_029337837.2 0 49 0 23 0 O75762 2.58e-107 Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation-sensitive protein p120) (p120) (Wasabi receptor) Homo sapiens (Human) calcium ion transmembrane transport [GO:0070588]; cell surface receptor signaling pathway [GO:0007166]; cellular calcium ion homeostasis [GO:0006874]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to organic substance [GO:0071310]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; ion transport [GO:0006811]; protein homotetramerization [GO:0051289]; response to cold [GO:0009409]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; sensory perception of pain [GO:0019233]; thermoception [GO:0050955] GO:0005262; GO:0005886; GO:0006811; GO:0006874; GO:0007166; GO:0009409; GO:0009410; GO:0010033; GO:0014070; GO:0015267; GO:0015278; GO:0019233; GO:0032421; GO:0042802; GO:0048265; GO:0050955; GO:0050966; GO:0050968; GO:0051289; GO:0070301; GO:0070588; GO:0071310; GO:0097604 22392 XM_029346896.2 334 81 19 0 361 A8KBE0 2.01e-86 Oxidation resistance protein 1 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005739 22393 XM_044321862.1 477 0 0 63 278 Q8BMK0 8.59e-36 Centrosomal protein of 85 kDa (Cep85) (Coiled-coil domain-containing protein 21) Mus musculus (Mouse) chromosome segregation [GO:0007059]; negative regulation of protein kinase activity [GO:0006469]; neuron migration [GO:0001764]; regulation of mitotic centrosome separation [GO:0046602] GO:0000242; GO:0000922; GO:0001764; GO:0005730; GO:0005794; GO:0005813; GO:0005829; GO:0006469; GO:0007059; GO:0046602 22394 XM_044328854.1 7 0 26 41 0 NA NA NA NA NA NA 22395 XM_029333154.2 49 37 13 27 57 NA NA NA NA NA NA 22396 XM_044318787.1 5639 5790 1886 3726 2265 NA NA NA NA NA NA 22397 XM_029334543.2 2329 1734 1032 1881 2207 NA NA NA NA NA NA 22398 XM_044319278.1 310 138 224 359 455 Q8TEP8 2.66e-153 Centrosomal protein of 192 kDa (Cep192) (Cep192/SPD-2) Homo sapiens (Human) centriole replication [GO:0007099]; centrosome-templated microtubule nucleation [GO:0090222]; mitotic spindle assembly [GO:0090307]; protein localization to centrosome [GO:0071539]; response to bacterium [GO:0009617] GO:0000242; GO:0005737; GO:0005813; GO:0005814; GO:0005829; GO:0007099; GO:0009617; GO:0019901; GO:0019902; GO:0071539; GO:0090222; GO:0090307; GO:0120098; GO:0120099 22399 XM_044314131.1 69 124 31 90 69 NA NA NA NA NA NA 22400 XM_029346465.2 1482 1559 656 1519 2129 A2A4P0 0 ATP-dependent RNA helicase DHX8 (EC 3.6.4.13) (DEAH box protein 8) Mus musculus (Mouse) mRNA splicing, via spliceosome [GO:0000398]; spliceosomal complex disassembly [GO:0000390] GO:0000390; GO:0000398; GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005654; GO:0005829; GO:0016604; GO:0016887; GO:0042802; GO:0071007; GO:0071013 22401 XM_029346465.2 1482 1559 656 1519 2129 A2A4P0 1.74e-29 ATP-dependent RNA helicase DHX8 (EC 3.6.4.13) (DEAH box protein 8) Mus musculus (Mouse) mRNA splicing, via spliceosome [GO:0000398]; spliceosomal complex disassembly [GO:0000390] GO:0000390; GO:0000398; GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005654; GO:0005829; GO:0016604; GO:0016887; GO:0042802; GO:0071007; GO:0071013 22402 XM_044329145.1 48 66 23 43 102 Q9EQD2 1.44e-27 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 22403 XM_044309748.1 0 0 0 0 11 NA NA NA NA NA NA 22404 XM_044325419.1 6641 5822 2984 6619 4939 O77460 3.73e-116 Inorganic pyrophosphatase (EC 3.6.1.1) (Nucleosome-remodeling factor 38 kDa subunit) (Pyrophosphate phospho-hydrolase) (PPase) Drosophila melanogaster (Fruit fly) chromatin remodeling [GO:0006338]; ecdysone receptor-mediated signaling pathway [GO:0035076]; nucleosome organization [GO:0034728]; phosphate-containing compound metabolic process [GO:0006796]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of hemocyte proliferation [GO:0035206] GO:0000287; GO:0004427; GO:0005634; GO:0005737; GO:0005829; GO:0006338; GO:0006796; GO:0016589; GO:0034728; GO:0035076; GO:0035206; GO:0045893 22405 XM_044321682.1 218 151 147 149 286 O00462 0 Beta-mannosidase (EC 3.2.1.25) (Lysosomal beta A mannosidase) (Mannanase) (Mannase) Homo sapiens (Human) glycoprotein catabolic process [GO:0006516]; oligosaccharide catabolic process [GO:0009313]; protein modification process [GO:0036211] GO:0004567; GO:0005537; GO:0005886; GO:0006516; GO:0009313; GO:0035577; GO:0036211; GO:0043202 22406 XM_044313487.1 0 0 0 0 24 Q09575 2.24e-26 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 22407 XM_044309110.1 0 30 0 37 0 NA NA NA NA NA NA 22408 XM_029330960.2 0 71 0 39 487 D3ZZL9 9.44e-90 GRIP and coiled-coil domain-containing protein 2 (185 kDa Golgi coiled-coil protein) Rattus norvegicus (Rat) Golgi ribbon formation [GO:0090161]; late endosome to Golgi transport [GO:0034499]; microtubule anchoring [GO:0034453]; microtubule organizing center organization [GO:0031023]; protein localization to Golgi apparatus [GO:0034067]; protein targeting to lysosome [GO:0006622]; recycling endosome to Golgi transport [GO:0071955]; regulation of protein exit from endoplasmic reticulum [GO:0070861]; retrograde transport, endosome to Golgi [GO:0042147] GO:0005794; GO:0005802; GO:0005829; GO:0006622; GO:0016020; GO:0031023; GO:0034067; GO:0034453; GO:0034499; GO:0042147; GO:0042802; GO:0070861; GO:0071955; GO:0090161 22409 XR_006393638.1 0 52 0 29 0 NA NA NA NA NA NA 22410 XM_029344740.2 1049 1065 425 611 365 P81127 4.16e-74 Gamma-soluble NSF attachment protein (SNAP-gamma) (N-ethylmaleimide-sensitive factor attachment protein gamma) Bos taurus (Bovine) intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192] GO:0005483; GO:0005794; GO:0006886; GO:0016192; GO:0019905; GO:0031201 22411 XM_044321745.1 0 14 0 0 47 NA NA NA NA NA NA 22412 XM_029331290.2 933 998 485 708 556 Q6PCF7 4.23e-92 Ubiquitin-conjugating enzyme E2 Z (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme Z) (Ubiquitin carrier protein Z) (Ubiquitin-protein ligase Z) Xenopus laevis (African clawed frog) apoptotic process [GO:0006915] GO:0005524; GO:0005634; GO:0005737; GO:0006915; GO:0061631 22413 XM_029354127.2 15 0 2 0 2 Q14191 7.13e-32 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN (DNA helicase, RecQ-like type 3) (RecQ protein-like 2) (Werner syndrome protein) [Includes: 3'-5' exonuclease (EC 3.1.-.-); ATP-dependent helicase (EC 3.6.4.12)] Homo sapiens (Human) aging [GO:0007568]; base-excision repair [GO:0006284]; brain development [GO:0007420]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; cellular response to starvation [GO:0009267]; cellular senescence [GO:0090398]; DNA duplex unwinding [GO:0032508]; DNA metabolic process [GO:0006259]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; G-quadruplex DNA unwinding [GO:0044806]; multicellular organism aging [GO:0010259]; positive regulation of hydrolase activity [GO:0051345]; positive regulation of strand invasion [GO:0098530]; protein localization to nucleolus [GO:1902570]; regulation of growth rate [GO:0040009]; replication fork processing [GO:0031297]; replicative senescence [GO:0090399]; response to oxidative stress [GO:0006979]; response to UV-C [GO:0010225]; t-circle formation [GO:0090656]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; telomeric D-loop disassembly [GO:0061820] GO:0000287; GO:0000400; GO:0000403; GO:0000405; GO:0000723; GO:0000724; GO:0000731; GO:0000781; GO:0003677; GO:0003678; GO:0003682; GO:0004527; GO:0005524; GO:0005634; GO:0005654; GO:0005657; GO:0005694; GO:0005730; GO:0005737; GO:0005813; GO:0006259; GO:0006260; GO:0006268; GO:0006281; GO:0006284; GO:0006302; GO:0006310; GO:0006974; GO:0006979; GO:0007420; GO:0007568; GO:0008408; GO:0009267; GO:0009378; GO:0010225; GO:0010259; GO:0016607; GO:0016887; GO:0030145; GO:0031297; GO:0032201; GO:0032405; GO:0032508; GO:0040009; GO:0042803; GO:0043005; GO:0043138; GO:0044806; GO:0044877; GO:0051345; GO:0051880; GO:0061749; GO:0061820; GO:0061821; GO:0061849; GO:0070337; GO:0071480; GO:0090398; GO:0090399; GO:0090656; GO:0098530; GO:1902570; GO:1905773 22414 XM_029347331.2 18 0 10 15 120 NA NA NA NA NA NA 22415 XM_044328922.1 3 0 7 0 19 NA NA NA NA NA NA 22416 XM_029334023.2 375 188 173 281 342 G8XYX6 8.49e-36 Monocarboxylate transporter 8 (MCT 8) (Solute carrier family 16 member 2) Danio rerio (Zebrafish) (Brachydanio rerio) brain development [GO:0007420]; central nervous system development [GO:0007417]; chordate embryonic development [GO:0043009]; locomotion [GO:0040011]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; Schwann cell differentiation [GO:0014037]; spinal cord development [GO:0021510]; spinal cord oligodendrocyte cell differentiation [GO:0021529]; thyroid gland development [GO:0030878] GO:0007417; GO:0007420; GO:0014037; GO:0015349; GO:0016324; GO:0021510; GO:0021529; GO:0030182; GO:0030878; GO:0040011; GO:0043009; GO:0048709; GO:0070324 22417 XM_029341153.2 69 128 77 177 220 Q9H1D0 3.42e-53 Transient receptor potential cation channel subfamily V member 6 (TrpV6) (CaT-like) (CaT-L) (Calcium transport protein 1) (CaT1) (Epithelial calcium channel 2) (ECaC2) Homo sapiens (Human) calcium ion homeostasis [GO:0055074]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; parathyroid hormone secretion [GO:0035898]; regulation of calcium ion-dependent exocytosis [GO:0017158]; response to calcium ion [GO:0051592] GO:0005216; GO:0005262; GO:0005516; GO:0005886; GO:0006816; GO:0017158; GO:0034704; GO:0035898; GO:0042802; GO:0046872; GO:0051592; GO:0055074; GO:0070588; GO:0098703 22418 XM_044329087.1 111 80 90 67 49 NA NA NA NA NA NA 22419 XM_044317385.1 28 30 47 157 90 NA NA NA NA NA NA 22420 XM_029339066.2 828 751 609 560 439 NA NA NA NA NA NA 22421 XM_044319519.1 0 5 0 0 23 NA NA NA NA NA NA 22422 XM_044327029.1 442 22 4 378 17 NA NA NA NA NA NA 22423 XM_044324044.1 43 143 120 165 823 D3ZZL9 1.32e-89 GRIP and coiled-coil domain-containing protein 2 (185 kDa Golgi coiled-coil protein) Rattus norvegicus (Rat) Golgi ribbon formation [GO:0090161]; late endosome to Golgi transport [GO:0034499]; microtubule anchoring [GO:0034453]; microtubule organizing center organization [GO:0031023]; protein localization to Golgi apparatus [GO:0034067]; protein targeting to lysosome [GO:0006622]; recycling endosome to Golgi transport [GO:0071955]; regulation of protein exit from endoplasmic reticulum [GO:0070861]; retrograde transport, endosome to Golgi [GO:0042147] GO:0005794; GO:0005802; GO:0005829; GO:0006622; GO:0016020; GO:0031023; GO:0034067; GO:0034453; GO:0034499; GO:0042147; GO:0042802; GO:0070861; GO:0071955; GO:0090161 22424 XM_044315514.1 0 0 0 8 0 NA NA NA NA NA NA 22425 XM_029345414.2 6005 4213 2543 4891 5113 Q5BJ78 6.02e-53 BSD domain-containing protein 1 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA NA 22426 XM_029336317.2 147 0 155 509 708 Q9Y603 7.5e-22 Transcription factor ETV7 (ETS translocation variant 7) (ETS-related protein Tel2) (Tel-related Ets factor) (Transcription factor Tel-2) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell differentiation [GO:0030154]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366] GO:0000122; GO:0000785; GO:0000977; GO:0000981; GO:0001227; GO:0005634; GO:0005654; GO:0006357; GO:0006366; GO:0009887; GO:0030154; GO:1990837 22427 XM_029323509.2 2087 1634 1100 1498 980 NA NA NA NA NA NA 22428 XM_029341980.2 2 0 0 0 16 Q9CYL5 5.68e-33 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Mus musculus (Mouse) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070374 22429 XM_029341980.2 2 0 0 0 16 Q9CYL5 1.7e-23 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Mus musculus (Mouse) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070374 22430 XM_029336935.2 45 41 78 175 69 Q5REG4 1.21e-53 Probable E3 ubiquitin-protein ligase DTX3 (EC 2.3.2.27) (Protein deltex-3) (Deltex3) (RING-type E3 ubiquitin transferase DTX3) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) Notch signaling pathway [GO:0007219]; protein ubiquitination [GO:0016567] GO:0005737; GO:0007219; GO:0016567; GO:0016740; GO:0046872 22431 XM_044310234.1 7 35 57 1 47 NA NA NA NA NA NA 22432 XM_029358687.2 347 379 294 207 335 P83038 0 Histone deacetylase 4 (HD4) (EC 3.5.1.98) Gallus gallus (Chicken) B cell activation [GO:0042113]; B cell differentiation [GO:0030183]; chromatin organization [GO:0006325]; histone deacetylation [GO:0016575]; histone H4 deacetylation [GO:0070933]; inflammatory response [GO:0006954]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of striated muscle tissue development [GO:0045843]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399] GO:0000118; GO:0000122; GO:0004407; GO:0005737; GO:0006325; GO:0006954; GO:0007399; GO:0016575; GO:0030183; GO:0042113; GO:0045843; GO:0045892; GO:0046872; GO:0070933; GO:0140297 22433 XM_029344550.2 138 48 42 187 193 Q0EEE2 1.02e-65 Patched domain-containing protein 3 (RND-type protein RNDEu-3) Mus musculus (Mouse) NA GO:0005783; GO:0005789; GO:0005886; GO:0016020; GO:0097225 22434 XM_044316929.1 0 5 0 10 0 NA NA NA NA NA NA 22435 XM_044319619.1 229 201 159 222 223 Q640L5 5.62e-85 Coiled-coil domain-containing protein 18 Mus musculus (Mouse) NA GO:0005737; GO:0034451 22436 XM_044325236.1 121 114 0 0 100 Q66I21 0 2-aminomuconic semialdehyde dehydrogenase (EC 1.2.1.32) (Aldehyde dehydrogenase family 8 member A1) Danio rerio (Zebrafish) (Brachydanio rerio) L-kynurenine catabolic process [GO:0097053]; liver development [GO:0001889]; retinoic acid metabolic process [GO:0042573] GO:0001758; GO:0001889; GO:0005737; GO:0016620; GO:0042573; GO:0047102; GO:0097053 22437 XM_029348335.2 160 0 148 0 138 NA NA NA NA NA NA 22438 XM_029346517.2 89 65 0 0 145 Q9PTS8 2.72e-93 Neuronal acetylcholine receptor subunit alpha-9 (Nicotinic acetylcholine receptor subunit alpha-9) (NACHR alpha-9) Gallus gallus (Chicken) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; regulation of nitric oxide metabolic process [GO:0080164]; response to auditory stimulus [GO:0010996]; signal transduction [GO:0007165] GO:0004888; GO:0005231; GO:0005262; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0010996; GO:0022848; GO:0030594; GO:0034220; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051899; GO:0080164; GO:1904315 22439 XM_029331605.2 363 447 348 516 460 NA NA NA NA NA NA 22440 XM_044307147.1 404 180 211 312 371 NA NA NA NA NA NA 22441 XM_044328339.1 0 28 0 0 0 Q58DM8 6.89e-128 Enoyl-CoA hydratase, mitochondrial (mECH) (mECH1) (EC 4.2.1.17) (EC 5.3.3.8) (Enoyl-CoA hydratase 1) (ECHS1) (Short-chain enoyl-CoA hydratase) (SCEH) Bos taurus (Bovine) fatty acid beta-oxidation [GO:0006635] GO:0004165; GO:0004300; GO:0005739; GO:0005759; GO:0006635; GO:0043956; GO:0120092 22442 XM_044318343.1 14 1 12 5 13 A3KN83 7.66e-43 Protein strawberry notch homolog 1 (Monocyte protein 3) (MOP-3) Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355]; regulation of response to stimulus [GO:0048583] GO:0005634; GO:0006355; GO:0031490; GO:0042393; GO:0048583 22443 XM_029335589.2 49 30 20 96 65 NA NA NA NA NA NA 22444 XM_029342606.2 119 57 0 0 100 Q9VBW3 3.42e-85 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 22445 XM_044307814.1 222 78 79 45 62 NA NA NA NA NA NA 22446 XM_044327540.1 17 22 11 21 19 NA NA NA NA NA NA 22447 XM_044312702.1 21 34 0 16 21 NA NA NA NA NA NA 22448 XM_029344067.2 12614 12371 6356 9257 10096 Q8AVT9 1.81e-151 Actin-related protein 2/3 complex subunit 1A-A Xenopus laevis (African clawed frog) Arp2/3 complex-mediated actin nucleation [GO:0034314] GO:0003779; GO:0005634; GO:0005737; GO:0005885; GO:0034314; GO:0035861 22449 XM_029354207.2 229 0 114 5 768 Q6LAF1 3.54e-50 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 22450 XM_044321447.1 40 154 143 560 649 P42674 2.19e-42 Blastula protease 10 (EC 3.4.24.-) Paracentrotus lividus (Common sea urchin) proteolysis [GO:0006508] GO:0004222; GO:0005615; GO:0005938; GO:0006508; GO:0008270; GO:0048471 22451 XM_029351281.2 59 59 60 56 107 O16099 3.1e-131 Maltase 2 (EC 3.2.1.20) Drosophila virilis (Fruit fly) NA GO:0032450 22452 XR_006397957.1 28360 26475 447 12697 8349 NA NA NA NA NA NA 22453 XM_029357281.2 99 99 113 67 77 P55115 3.87e-54 Zinc metalloproteinase nas-15 (EC 3.4.24.-) (Nematode astacin 15) Caenorhabditis elegans proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0006508; GO:0008270 22454 XM_044321008.1 281 177 48 244 151 NA NA NA NA NA NA 22455 XM_044324696.1 30 0 4 5 1 Q8NDA2 5.2e-29 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 22456 XM_044324696.1 30 0 4 5 1 Q8NDA2 1.62e-26 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 22457 XM_044324696.1 30 0 4 5 1 Q8NDA2 1.65e-26 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 22458 XM_044324696.1 30 0 4 5 1 Q8NDA2 2.04e-25 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 22459 XM_044324696.1 30 0 4 5 1 Q8NDA2 2.04e-25 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 22460 XM_044324696.1 30 0 4 5 1 Q8NDA2 1.99e-23 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 22461 XM_044324696.1 30 0 4 5 1 Q8NDA2 1.99e-23 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 22462 XM_044324696.1 30 0 4 5 1 Q8NDA2 3.4e-23 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 22463 XM_044324696.1 30 0 4 5 1 Q8NDA2 3.4e-23 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 22464 XM_044324696.1 30 0 4 5 1 Q8NDA2 3.97e-22 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 22465 XM_044324696.1 30 0 4 5 1 Q8NDA2 1.48e-21 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 22466 XM_044324696.1 30 0 4 5 1 Q8NDA2 1.48e-21 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 22467 XR_006397965.1 821 1226 801 1130 1167 NA NA NA NA NA NA 22468 XR_006397917.1 19 2 53 1 28 NA NA NA NA NA NA 22469 XM_044327618.1 236 315 169 81 158 NA NA NA NA NA NA 22470 XM_029339770.2 0 168 195 0 0 NA NA NA NA NA NA 22471 XM_044324861.1 18 13 140 16 83 NA NA NA NA NA NA 22472 XR_006394985.1 258 110 0 0 209 NA NA NA NA NA NA 22473 XM_044312168.1 0 5 10 0 3 NA NA NA NA NA NA 22474 XM_029329028.2 288 79 136 339 336 NA NA NA NA NA NA 22475 XM_044319438.1 92 15 26 11 61 NA NA NA NA NA NA 22476 XM_029324637.2 49 86 11 23 49 NA NA NA NA NA NA 22477 XM_044320677.1 7 2 0 0 2 NA NA NA NA NA NA 22478 XM_044323824.1 0 0 0 165 0 Q15434 4.96e-77 RNA-binding motif, single-stranded-interacting protein 2 (Suppressor of CDC2 with RNA-binding motif 3) Homo sapiens (Human) RNA processing [GO:0006396] GO:0003723; GO:0003730; GO:0005634; GO:0005829; GO:0006396; GO:0008143; GO:0008266; GO:1990904 22479 XM_044322547.1 259 166 81 170 454 Q0V8L6 4.82e-132 Phospholipase D2 (PLD 2) (EC 3.1.4.4) (Choline phosphatase 2) (Phosphatidylcholine-hydrolyzing phospholipase D2) Bos taurus (Bovine) inositol lipid-mediated signaling [GO:0048017]; phosphatidic acid biosynthetic process [GO:0006654]; phospholipid catabolic process [GO:0009395]; regulation of vesicle-mediated transport [GO:0060627] GO:0004630; GO:0005737; GO:0005886; GO:0006654; GO:0009395; GO:0035091; GO:0043231; GO:0048017; GO:0060627; GO:0070290 22480 XM_044321984.1 15 15 174 23 14 NA NA NA NA NA NA 22481 XM_029338996.2 58 22 0 48 0 NA NA NA NA NA NA 22482 XM_044321749.1 78 54 53 0 0 NA NA NA NA NA NA 22483 XM_044321797.1 38 0 1031 0 2512 O02649 0 Heat shock protein 60A Drosophila melanogaster (Fruit fly) apoptotic mitochondrial changes [GO:0008637]; cellular response to heat [GO:0034605]; mitochondrial unfolded protein response [GO:0034514]; mitochondrion organization [GO:0007005]; protein folding [GO:0006457]; protein import into mitochondrial intermembrane space [GO:0045041]; protein refolding [GO:0042026] GO:0005524; GO:0005739; GO:0005743; GO:0005759; GO:0006457; GO:0007005; GO:0008637; GO:0016887; GO:0034514; GO:0034605; GO:0042026; GO:0045041; GO:0051087; GO:0140662 22484 XM_044314465.1 94 0 0 37 0 NA NA NA NA NA NA 22485 XM_044314457.1 653 26 49 31 30 NA NA NA NA NA NA 22486 XM_029353718.2 10048 9546 7574 5396 4031 Q3T0Z7 5.33e-85 Dihydropteridine reductase (EC 1.5.1.34) (HDHPR) (Quinoid dihydropteridine reductase) Bos taurus (Bovine) L-phenylalanine catabolic process [GO:0006559]; tetrahydrobiopterin biosynthetic process [GO:0006729] GO:0004155; GO:0005737; GO:0006559; GO:0006729; GO:0016616; GO:0070402; GO:0070404 22487 XM_044326214.1 677 371 378 698 658 Q9Y6N7 2.26e-28 Roundabout homolog 1 (Deleted in U twenty twenty) (H-Robo-1) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; axon midline choice point recognition [GO:0016199]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; endocardial cushion formation [GO:0003272]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of gene expression [GO:0010629]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; negative regulation of negative chemotaxis [GO:0050925]; nervous system development [GO:0007399]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; pulmonary valve morphogenesis [GO:0003184]; Roundabout signaling pathway [GO:0035385]; ventricular septum morphogenesis [GO:0060412] GO:0002042; GO:0003148; GO:0003180; GO:0003184; GO:0003272; GO:0005737; GO:0005886; GO:0006919; GO:0007155; GO:0007156; GO:0007399; GO:0008046; GO:0009986; GO:0010628; GO:0010629; GO:0016199; GO:0021836; GO:0030275; GO:0030336; GO:0030424; GO:0033116; GO:0033600; GO:0035025; GO:0035385; GO:0035481; GO:0035904; GO:0042802; GO:0043406; GO:0050772; GO:0050925; GO:0060412; GO:0070100; GO:1900748 22488 XM_044326214.1 677 371 378 698 658 Q9Y6N7 5.03e-26 Roundabout homolog 1 (Deleted in U twenty twenty) (H-Robo-1) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; axon midline choice point recognition [GO:0016199]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; endocardial cushion formation [GO:0003272]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of gene expression [GO:0010629]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; negative regulation of negative chemotaxis [GO:0050925]; nervous system development [GO:0007399]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; pulmonary valve morphogenesis [GO:0003184]; Roundabout signaling pathway [GO:0035385]; ventricular septum morphogenesis [GO:0060412] GO:0002042; GO:0003148; GO:0003180; GO:0003184; GO:0003272; GO:0005737; GO:0005886; GO:0006919; GO:0007155; GO:0007156; GO:0007399; GO:0008046; GO:0009986; GO:0010628; GO:0010629; GO:0016199; GO:0021836; GO:0030275; GO:0030336; GO:0030424; GO:0033116; GO:0033600; GO:0035025; GO:0035385; GO:0035481; GO:0035904; GO:0042802; GO:0043406; GO:0050772; GO:0050925; GO:0060412; GO:0070100; GO:1900748 22489 XM_044313694.1 0 0 74 0 150 NA NA NA NA NA NA 22490 XR_006394485.1 3754 10331 787 2543 672 NA NA NA NA NA NA 22491 XM_029338574.2 1077 538 392 755 680 Q9H6U6 0 BCAS3 microtubule associated cell migration factor (Breast carcinoma-amplified sequence 3) (GAOB1) Homo sapiens (Human) activation of GTPase activity [GO:0090630]; angiogenesis [GO:0001525]; autophagy [GO:0006914]; cellular response to estrogen stimulus [GO:0071391]; Golgi organization [GO:0007030]; microtubule organizing center organization [GO:0031023]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of GTPase activity [GO:0034260]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of catalytic activity [GO:0043085]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of establishment of cell polarity [GO:2000114]; response to estrogen [GO:0043627]; response to starvation [GO:0042594]; tube formation [GO:0035148] GO:0000407; GO:0000791; GO:0001525; GO:0003682; GO:0005634; GO:0005737; GO:0005881; GO:0006914; GO:0007030; GO:0010595; GO:0010698; GO:0016922; GO:0031023; GO:0031252; GO:0034260; GO:0035035; GO:0035091; GO:0035148; GO:0042393; GO:0042594; GO:0043085; GO:0043547; GO:0043627; GO:0045111; GO:0045944; GO:0048487; GO:0051491; GO:0051895; GO:0071391; GO:0090316; GO:0090630; GO:2000114; GO:2000251 22492 XM_029358054.2 256 344 169 319 163 Q9W0Y2 1.34e-30 Putative gamma-glutamylcyclotransferase CG2811 (EC 2.3.2.-) Drosophila melanogaster (Fruit fly) NA GO:0005829; GO:0016746; GO:0061929 22493 XM_029340081.2 156 115 89 152 86 O60462 5.78e-39 Neuropilin-2 (Vascular endothelial cell growth factor 165 receptor 2) Homo sapiens (Human) angiogenesis [GO:0001525]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; cellular response to leukemia inhibitory factor [GO:1990830]; dorsal root ganglion morphogenesis [GO:1904835]; facial nerve structural organization [GO:0021612]; facioacoustic ganglion development [GO:1903375]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; negative chemotaxis [GO:0050919]; nerve development [GO:0021675]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; regulation of postsynapse organization [GO:0099175]; semaphorin-plexin signaling pathway involved in neuron projection guidance [GO:1902285]; sensory neuron axon guidance [GO:0097374]; sympathetic ganglion development [GO:0061549]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491]; trigeminal ganglion development [GO:0061551]; ventral trunk neural crest cell migration [GO:0036486]; vestibulocochlear nerve structural organization [GO:0021649] GO:0001525; GO:0001938; GO:0002116; GO:0003148; GO:0005021; GO:0005576; GO:0005886; GO:0007155; GO:0007411; GO:0008201; GO:0010595; GO:0016020; GO:0017154; GO:0019838; GO:0019955; GO:0021612; GO:0021649; GO:0021675; GO:0021828; GO:0030424; GO:0036486; GO:0038023; GO:0042802; GO:0045211; GO:0046872; GO:0048846; GO:0050919; GO:0061549; GO:0061551; GO:0097374; GO:0097490; GO:0097491; GO:0098978; GO:0099175; GO:1901166; GO:1902285; GO:1903375; GO:1904835; GO:1990830 22494 XM_044328780.1 30 5 28 51 36 NA NA NA NA NA NA 22495 XM_029342685.2 2324 2139 1452 2701 2054 Q9NZL6 1.15e-116 Ral guanine nucleotide dissociation stimulator-like 1 (RalGDS-like 1) Homo sapiens (Human) positive regulation of GTPase activity [GO:0043547]; Ras protein signal transduction [GO:0007265]; small GTPase mediated signal transduction [GO:0007264] GO:0005085; GO:0005829; GO:0005886; GO:0007264; GO:0007265; GO:0043547 22496 XM_029358137.2 57 128 96 91 54 NA NA NA NA NA NA 22497 XM_044309272.1 142 54 246 57 283 NA NA NA NA NA NA 22498 XM_029336560.2 22 16 635 0 10 Q29496 3.33e-107 Cytochrome P450 3A24 (EC 1.14.14.1) (CYPIIIA24) Ovis aries (Sheep) NA GO:0004497; GO:0005506; GO:0005789; GO:0020037; GO:0070330 22499 XM_044316416.1 4 17 12 7 4 NA NA NA NA NA NA 22500 XM_044323198.1 3 17 3 14 76 Q99315 1.79e-22 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 22501 XR_006396133.1 897 643 625 1137 686 Q99570 0 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 22502 XR_006396133.1 897 643 625 1137 686 Q99570 0 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 22503 XR_006396133.1 897 643 625 1137 686 Q99570 1.01e-45 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 22504 XM_029328651.2 0 114 0 0 0 Q5R6J1 8.43e-88 Sodium-dependent neutral amino acid transporter B(0)AT1 (Solute carrier family 6 member 19) (System B(0) neutral amino acid transporter AT1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0015175; GO:0015293; GO:0016324 22505 XM_029351636.2 0 35 112 186 49 NA NA NA NA NA NA 22506 XM_029325780.2 644 410 285 613 511 Q91YK0 3.77e-174 Leucine-rich repeat-containing protein 49 (Tubulin polyglutamylase complex subunit 4) (PGs4) (p79) Mus musculus (Mouse) outer dynein arm assembly [GO:0036158] GO:0005737; GO:0005829; GO:0005874; GO:0034451; GO:0036158 22507 XM_044320611.1 249 279 150 71 82 NA NA NA NA NA NA 22508 XM_044325880.1 50 102 53 65 64 NA NA NA NA NA NA 22509 XM_029342668.2 32 4 15 83 36 NA NA NA NA NA NA 22510 XM_029323972.2 1124 406 277 739 589 Q6P5E8 0 Diacylglycerol kinase theta (DAG kinase theta) (EC 2.7.1.107) (Diglyceride kinase theta) (DGK-theta) Mus musculus (Mouse) cAMP-mediated signaling [GO:0019933]; diacylglycerol metabolic process [GO:0046339]; G protein-coupled receptor signaling pathway [GO:0007186]; glycerolipid metabolic process [GO:0046486]; intracellular signal transduction [GO:0035556]; lipid phosphorylation [GO:0046834]; negative regulation of gene expression [GO:0010629]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; peptidyl-serine phosphorylation [GO:0018105]; phosphatidic acid biosynthetic process [GO:0006654]; positive regulation of gene expression [GO:0010628]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; protein kinase C signaling [GO:0070528]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; regulation of cholesterol metabolic process [GO:0090181]; regulation of cortisol biosynthetic process [GO:2000064]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; regulation of gluconeogenesis [GO:0006111]; regulation of progesterone biosynthetic process [GO:2000182]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of TORC1 signaling [GO:1903432]; regulation of transcription by RNA polymerase II [GO:0006357]; response to ATP [GO:0033198]; response to cAMP [GO:0051591]; thrombin-activated receptor signaling pathway [GO:0070493] GO:0004143; GO:0005524; GO:0005634; GO:0005737; GO:0005768; GO:0005829; GO:0005856; GO:0005886; GO:0006111; GO:0006357; GO:0006654; GO:0007186; GO:0007205; GO:0008277; GO:0010628; GO:0010629; GO:0010801; GO:0012506; GO:0016363; GO:0016607; GO:0018105; GO:0019900; GO:0019933; GO:0030297; GO:0033198; GO:0035556; GO:0043274; GO:0046339; GO:0046486; GO:0046834; GO:0046872; GO:0050731; GO:0051591; GO:0070493; GO:0070528; GO:0090181; GO:0098793; GO:0098794; GO:0098978; GO:0140297; GO:1900242; GO:1903432; GO:2000064; GO:2000182 22511 XM_029332572.2 616 355 299 683 905 P60123 0 RuvB-like 1 (EC 3.6.4.12) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (DNA helicase p50) (Pontin 52) (TIP49a) Rattus norvegicus (Rat) box C/D snoRNP assembly [GO:0000492]; cell cycle [GO:0007049]; cell division [GO:0051301]; chromatin remodeling [GO:0006338]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; histone acetylation [GO:0016573]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of plasminogen activation [GO:0010756]; positive regulation of telomere maintenance in response to DNA damage [GO:1904507]; regulation of cell cycle [GO:0051726]; regulation of chromosome organization [GO:0033044]; regulation of DNA repair [GO:0006282]; regulation of DNA replication [GO:0006275]; regulation of DNA strand elongation [GO:0060382]; regulation of embryonic development [GO:0045995]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of transcription by RNA polymerase II [GO:0006357]; telomere maintenance [GO:0000723] GO:0000492; GO:0000723; GO:0000786; GO:0000812; GO:0001094; GO:0003678; GO:0003713; GO:0005524; GO:0005634; GO:0005815; GO:0006275; GO:0006281; GO:0006282; GO:0006310; GO:0006338; GO:0006357; GO:0007049; GO:0010756; GO:0016363; GO:0016573; GO:0016887; GO:0017025; GO:0031011; GO:0031965; GO:0032991; GO:0033044; GO:0035267; GO:0043138; GO:0043531; GO:0043967; GO:0043968; GO:0045739; GO:0045893; GO:0045995; GO:0051117; GO:0051301; GO:0051726; GO:0060382; GO:0071339; GO:0090263; GO:0097255; GO:0101031; GO:0120293; GO:1904507; GO:1905168; GO:1990062; GO:1990904; GO:2000269 22512 XM_029330080.2 18 0 2 7 16 NA NA NA NA NA NA 22513 XM_029328762.2 527 328 111 226 263 Q5ZL05 2.23e-58 Calcium release-activated calcium channel protein 1 (Protein orai-1) (Transmembrane protein 142A) Gallus gallus (Chicken) adaptive immune response [GO:0002250]; positive regulation of calcium ion transport [GO:0051928]; store-operated calcium entry [GO:0002115] GO:0002115; GO:0002250; GO:0005886; GO:0015279; GO:0016020; GO:0051928 22514 XM_029339493.2 560 226 170 269 195 A8MY62 3.62e-51 Putative beta-lactamase-like 1 Homo sapiens (Human) NA NA 22515 XM_044319256.1 1241 1212 330 59 1170 NA NA NA NA NA NA 22516 XM_044322124.1 541 58 399 557 660 Q6NRS1 5.21e-121 Inhibitor of Bruton tyrosine kinase (IBtk) Xenopus laevis (African clawed frog) NA GO:0005737; GO:0016020 22517 XM_044322124.1 541 58 399 557 660 Q6NRS1 1.42e-75 Inhibitor of Bruton tyrosine kinase (IBtk) Xenopus laevis (African clawed frog) NA GO:0005737; GO:0016020 22518 XM_044328155.1 33 3 0 0 0 NA NA NA NA NA NA 22519 XM_044316610.1 15 15 16 16 54 NA NA NA NA NA NA 22520 XR_006397874.1 9 931 3 5 1 NA NA NA NA NA NA 22521 XM_044324028.1 110 318 46 612 152 NA NA NA NA NA NA 22522 XM_044326133.1 5 2 0 0 30 NA NA NA NA NA NA 22523 XM_044319876.1 20 19 15 9 5 NA NA NA NA NA NA 22524 XM_029342411.2 32 115 996 236 571 P83941 4.19e-65 Elongin-C (EloC) (Elongin 15 kDa subunit) (RNA polymerase II transcription factor SIII subunit C) (SIII p15) (Stromal membrane-associated protein SMAP1B homolog) (Transcription elongation factor B polypeptide 1) Rattus norvegicus (Rat) positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; protein ubiquitination [GO:0016567]; transcription initiation at RNA polymerase II promoter [GO:0006367]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0001222; GO:0006367; GO:0006511; GO:0016567; GO:0030674; GO:0030891; GO:0031466; GO:0032968; GO:0044877; GO:0070449 22525 XM_044326985.1 23 6 140 9 5 NA NA NA NA NA NA 22526 XM_029356777.2 541 291 278 513 657 Q01780 0 Exosome component 10 (EC 3.1.13.-) (Autoantigen PM/Scl 2) (P100 polymyositis-scleroderma overlap syndrome-associated autoantigen) (Polymyositis/scleroderma autoantigen 100 kDa) (PM/Scl-100) (Polymyositis/scleroderma autoantigen 2) Homo sapiens (Human) CUT catabolic process [GO:0071034]; dosage compensation by inactivation of X chromosome [GO:0009048]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; histone mRNA catabolic process [GO:0071044]; maturation of 5.8S rRNA [GO:0000460]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear mRNA surveillance [GO:0071028]; nuclear polyadenylation-dependent antisense transcript catabolic process [GO:0071040]; nuclear polyadenylation-dependent CUT catabolic process [GO:0071039]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent snoRNA catabolic process [GO:0071036]; nuclear polyadenylation-dependent snRNA catabolic process [GO:0071037]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; regulation of telomerase RNA localization to Cajal body [GO:1904872]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]; rRNA processing [GO:0006364] GO:0000166; GO:0000175; GO:0000176; GO:0000177; GO:0000178; GO:0000184; GO:0000460; GO:0000467; GO:0000791; GO:0000956; GO:0003723; GO:0003727; GO:0004532; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0006364; GO:0006396; GO:0006401; GO:0009048; GO:0016020; GO:0032211; GO:0070034; GO:0071028; GO:0071034; GO:0071035; GO:0071036; GO:0071037; GO:0071038; GO:0071039; GO:0071040; GO:0071044; GO:0071051; GO:0101019; GO:1904872 22527 XM_029326247.2 8518 8323 7691 6094 3606 Q25532 3.9e-30 V-type proton ATPase subunit G (V-ATPase subunit G) (V-ATPase 13 kDa subunit) (Vacuolar proton pump subunit G) Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm) NA GO:0016324; GO:0016471; GO:0046961 22528 XM_029326158.2 23 24 3 1 18 Q15485 5.39e-78 Ficolin-2 (37 kDa elastin-binding protein) (Collagen/fibrinogen domain-containing protein 2) (EBP-37) (Ficolin-B) (Ficolin-beta) (Hucolin) (L-ficolin) (Serum lectin p35) Homo sapiens (Human) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; positive regulation of opsonization [GO:1903028]; proteolysis [GO:0006508]; recognition of apoptotic cell [GO:0043654] GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005576; GO:0005581; GO:0005615; GO:0006508; GO:0008228; GO:0009897; GO:0042802; GO:0043394; GO:0043654; GO:0046872; GO:0048306; GO:0050829; GO:0050830; GO:0062023; GO:0070062; GO:0072562; GO:0097367; GO:1903028; GO:1905370; GO:2001065 22529 XR_006394166.1 118 4 134 291 270 NA NA NA NA NA NA 22530 XM_044320803.1 10 31 4 35 6 NA NA NA NA NA NA 22531 XM_029326275.2 61 40 47 64 47 NA NA NA NA NA NA 22532 XM_029324291.2 14245 9587 5986 6756 11598 P18258 0 Tubulin alpha-1 chain (EC 3.6.5.-) Paracentrotus lividus (Common sea urchin) microtubule-based process [GO:0007017] GO:0005200; GO:0005525; GO:0005737; GO:0005874; GO:0007017; GO:0016787; GO:0046872 22533 XM_029329253.2 59 41 21 76 44 Q93126 8.28e-46 Probable G-protein coupled receptor No9 Amphibalanus amphitrite (Striped barnacle) (Balanus amphitrite) NA GO:0004935; GO:0005886 22534 XM_044318861.1 12 10 3 18 9 NA NA NA NA NA NA 22535 XR_003826507.2 1 0 0 12 3 NA NA NA NA NA NA 22536 XM_044319591.1 407 332 32 46 479 P46023 1.62e-96 G-protein coupled receptor GRL101 Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004930; GO:0005886 22537 XM_029344712.2 141 117 109 63 172 A6QQV6 0 Protein arginine N-methyltransferase 7 (EC 2.1.1.321) (Histone-arginine N-methyltransferase PRMT7) ([Myelin basic protein]-arginine N-methyltransferase PRMT7) Bos taurus (Bovine) cell differentiation [GO:0030154]; peptidyl-arginine methylation [GO:0018216]; regulation of gene expression by genomic imprinting [GO:0006349]; spliceosomal snRNP assembly [GO:0000387] GO:0000387; GO:0004984; GO:0005634; GO:0005829; GO:0005886; GO:0006349; GO:0018216; GO:0030154; GO:0035241; GO:0035243; GO:0044020 22538 XM_029345268.2 15 8 3 0 35 NA NA NA NA NA NA 22539 XR_006396967.1 5 0 12 0 0 NA NA NA NA NA NA 22540 XM_044307295.1 28 97 13 29 38 NA NA NA NA NA NA 22541 XM_029346714.2 985 2063 0 2007 2487 P54965 2.78e-41 Conjugated bile acid hydrolase (CBAH) (EC 3.5.1.-) (Bile salt hydrolase) (BSH) (CBAH-1) (Choloylglycine hydrolase) (EC 3.5.1.24) Clostridium perfringens (strain 13 / Type A) bile acid biosynthetic process [GO:0006699] GO:0006699; GO:0045302; GO:0047742 22542 XM_029328549.2 444 415 400 155 362 Q3TLD5 3.64e-33 Unconventional prefoldin RPB5 interactor (Protein NNX3) (Protein phosphatase 1 regulatory subunit 19) (RNA polymerase II subunit 5-mediating protein) (RPB5-mediating protein) Mus musculus (Mouse) cellular response to growth factor stimulus [GO:0071363]; cellular response to steroid hormone stimulus [GO:0071383]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of phosphatase activity [GO:0010923]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of cell growth [GO:0001558]; regulation of transcription by RNA polymerase II [GO:0006357]; response to virus [GO:0009615] GO:0000122; GO:0000993; GO:0001558; GO:0003682; GO:0003714; GO:0004864; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005829; GO:0006357; GO:0009615; GO:0010923; GO:0019212; GO:0030425; GO:0051219; GO:0071363; GO:0071383; GO:1990062; GO:2001243 22543 XM_029351845.2 13 5 13 43 43 NA NA NA NA NA NA 22544 XM_044313875.1 1101 741 439 608 514 NA NA NA NA NA NA 22545 XM_044327533.1 0 10 0 0 0 NA NA NA NA NA NA 22546 XM_029327032.2 858 717 366 599 620 Q8VDL9 4.02e-67 Zinc finger protein GLIS2 (GLI-similar 2) (Neuronal Krueppel-like protein) (Zinc finger protein GLI5) Mus musculus (Mouse) cell differentiation involved in kidney development [GO:0061005]; central nervous system development [GO:0007417]; hematopoietic stem cell homeostasis [GO:0061484]; kidney development [GO:0001822]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000976; GO:0000977; GO:0000978; GO:0000981; GO:0001228; GO:0001822; GO:0003677; GO:0003700; GO:0005634; GO:0005654; GO:0005667; GO:0005737; GO:0006357; GO:0007417; GO:0016607; GO:0043433; GO:0045879; GO:0045892; GO:0045893; GO:0045944; GO:0046872; GO:0061005; GO:0061484; GO:0097730; GO:1900182; GO:1990837 22547 XM_029348837.2 506 335 297 485 679 Q94BV5 5.44e-75 Flavin-containing monooxygenase FMO GS-OX-like 4 (EC 1.8.-.-) (Flavin-monooxygenase glucosinolate S-oxygenase-like 4) Arabidopsis thaliana (Mouse-ear cress) NA GO:0000325; GO:0004499; GO:0050660; GO:0050661 22548 XM_044314799.1 60 23 10 41 111 NA NA NA NA NA NA 22549 XM_044323344.1 68 1 20 62 0 NA NA NA NA NA NA 22550 XM_029342074.2 19 46 0 25 63 P85299 1.06e-32 Proline-rich protein 5 (Protein observed with Rictor-1) (Protor-1) Homo sapiens (Human) cell cycle [GO:0007049]; cellular response to nutrient levels [GO:0031669]; cytoskeleton organization [GO:0007010]; negative regulation of apoptotic process [GO:0043066]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphorylation [GO:0016310]; positive regulation of cell growth [GO:0030307]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein phosphorylation [GO:0001934]; protein phosphorylation [GO:0006468]; TORC2 signaling [GO:0038203] GO:0001934; GO:0005829; GO:0006468; GO:0007010; GO:0007049; GO:0014065; GO:0014068; GO:0016310; GO:0030307; GO:0031669; GO:0031932; GO:0038203; GO:0043066 22551 XR_006393069.1 41 2 25 5 151 NA NA NA NA NA NA 22552 XM_029355408.2 0 0 0 10 0 Q05793 0 Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG) [Cleaved into: Endorepellin; LG3 peptide] Mus musculus (Mouse) angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; brain development [GO:0007420]; cardiac muscle tissue development [GO:0048738]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; chondrocyte differentiation [GO:0002062]; embryonic skeletal system morphogenesis [GO:0048704]; endochondral ossification [GO:0001958]; extracellular matrix organization [GO:0030198]; negative regulation of amyloid fibril formation [GO:1905907]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell death [GO:0060548]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of endothelial cell proliferation [GO:0001938]; protein localization [GO:0008104]; receptor-mediated endocytosis [GO:0006898]; smoothened signaling pathway [GO:0007224]; tissue development [GO:0009888] GO:0001525; GO:0001938; GO:0001958; GO:0002020; GO:0002062; GO:0005509; GO:0005576; GO:0005604; GO:0005796; GO:0006898; GO:0007162; GO:0007224; GO:0007420; GO:0008022; GO:0008104; GO:0008285; GO:0009887; GO:0009888; GO:0030198; GO:0031012; GO:0048704; GO:0048738; GO:0060351; GO:0060548; GO:0062023; GO:0070052; GO:1905907 22553 XM_029355408.2 0 0 0 10 0 Q05793 0 Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG) [Cleaved into: Endorepellin; LG3 peptide] Mus musculus (Mouse) angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; brain development [GO:0007420]; cardiac muscle tissue development [GO:0048738]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; chondrocyte differentiation [GO:0002062]; embryonic skeletal system morphogenesis [GO:0048704]; endochondral ossification [GO:0001958]; extracellular matrix organization [GO:0030198]; negative regulation of amyloid fibril formation [GO:1905907]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell death [GO:0060548]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of endothelial cell proliferation [GO:0001938]; protein localization [GO:0008104]; receptor-mediated endocytosis [GO:0006898]; smoothened signaling pathway [GO:0007224]; tissue development [GO:0009888] GO:0001525; GO:0001938; GO:0001958; GO:0002020; GO:0002062; GO:0005509; GO:0005576; GO:0005604; GO:0005796; GO:0006898; GO:0007162; GO:0007224; GO:0007420; GO:0008022; GO:0008104; GO:0008285; GO:0009887; GO:0009888; GO:0030198; GO:0031012; GO:0048704; GO:0048738; GO:0060351; GO:0060548; GO:0062023; GO:0070052; GO:1905907 22554 XM_029355408.2 0 0 0 10 0 Q05793 9.66e-128 Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG) [Cleaved into: Endorepellin; LG3 peptide] Mus musculus (Mouse) angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; brain development [GO:0007420]; cardiac muscle tissue development [GO:0048738]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; chondrocyte differentiation [GO:0002062]; embryonic skeletal system morphogenesis [GO:0048704]; endochondral ossification [GO:0001958]; extracellular matrix organization [GO:0030198]; negative regulation of amyloid fibril formation [GO:1905907]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell death [GO:0060548]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of endothelial cell proliferation [GO:0001938]; protein localization [GO:0008104]; receptor-mediated endocytosis [GO:0006898]; smoothened signaling pathway [GO:0007224]; tissue development [GO:0009888] GO:0001525; GO:0001938; GO:0001958; GO:0002020; GO:0002062; GO:0005509; GO:0005576; GO:0005604; GO:0005796; GO:0006898; GO:0007162; GO:0007224; GO:0007420; GO:0008022; GO:0008104; GO:0008285; GO:0009887; GO:0009888; GO:0030198; GO:0031012; GO:0048704; GO:0048738; GO:0060351; GO:0060548; GO:0062023; GO:0070052; GO:1905907 22555 XM_029355408.2 0 0 0 10 0 Q05793 9.72e-60 Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG) [Cleaved into: Endorepellin; LG3 peptide] Mus musculus (Mouse) angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; brain development [GO:0007420]; cardiac muscle tissue development [GO:0048738]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; chondrocyte differentiation [GO:0002062]; embryonic skeletal system morphogenesis [GO:0048704]; endochondral ossification [GO:0001958]; extracellular matrix organization [GO:0030198]; negative regulation of amyloid fibril formation [GO:1905907]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell death [GO:0060548]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of endothelial cell proliferation [GO:0001938]; protein localization [GO:0008104]; receptor-mediated endocytosis [GO:0006898]; smoothened signaling pathway [GO:0007224]; tissue development [GO:0009888] GO:0001525; GO:0001938; GO:0001958; GO:0002020; GO:0002062; GO:0005509; GO:0005576; GO:0005604; GO:0005796; GO:0006898; GO:0007162; GO:0007224; GO:0007420; GO:0008022; GO:0008104; GO:0008285; GO:0009887; GO:0009888; GO:0030198; GO:0031012; GO:0048704; GO:0048738; GO:0060351; GO:0060548; GO:0062023; GO:0070052; GO:1905907 22556 XM_029355408.2 0 0 0 10 0 Q05793 4.05e-51 Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG) [Cleaved into: Endorepellin; LG3 peptide] Mus musculus (Mouse) angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; brain development [GO:0007420]; cardiac muscle tissue development [GO:0048738]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; chondrocyte differentiation [GO:0002062]; embryonic skeletal system morphogenesis [GO:0048704]; endochondral ossification [GO:0001958]; extracellular matrix organization [GO:0030198]; negative regulation of amyloid fibril formation [GO:1905907]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell death [GO:0060548]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of endothelial cell proliferation [GO:0001938]; protein localization [GO:0008104]; receptor-mediated endocytosis [GO:0006898]; smoothened signaling pathway [GO:0007224]; tissue development [GO:0009888] GO:0001525; GO:0001938; GO:0001958; GO:0002020; GO:0002062; GO:0005509; GO:0005576; GO:0005604; GO:0005796; GO:0006898; GO:0007162; GO:0007224; GO:0007420; GO:0008022; GO:0008104; GO:0008285; GO:0009887; GO:0009888; GO:0030198; GO:0031012; GO:0048704; GO:0048738; GO:0060351; GO:0060548; GO:0062023; GO:0070052; GO:1905907 22557 XM_029355408.2 0 0 0 10 0 Q05793 5.25e-33 Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG) [Cleaved into: Endorepellin; LG3 peptide] Mus musculus (Mouse) angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; brain development [GO:0007420]; cardiac muscle tissue development [GO:0048738]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; chondrocyte differentiation [GO:0002062]; embryonic skeletal system morphogenesis [GO:0048704]; endochondral ossification [GO:0001958]; extracellular matrix organization [GO:0030198]; negative regulation of amyloid fibril formation [GO:1905907]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell death [GO:0060548]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of endothelial cell proliferation [GO:0001938]; protein localization [GO:0008104]; receptor-mediated endocytosis [GO:0006898]; smoothened signaling pathway [GO:0007224]; tissue development [GO:0009888] GO:0001525; GO:0001938; GO:0001958; GO:0002020; GO:0002062; GO:0005509; GO:0005576; GO:0005604; GO:0005796; GO:0006898; GO:0007162; GO:0007224; GO:0007420; GO:0008022; GO:0008104; GO:0008285; GO:0009887; GO:0009888; GO:0030198; GO:0031012; GO:0048704; GO:0048738; GO:0060351; GO:0060548; GO:0062023; GO:0070052; GO:1905907 22558 XM_029355408.2 0 0 0 10 0 Q05793 2.03e-31 Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG) [Cleaved into: Endorepellin; LG3 peptide] Mus musculus (Mouse) angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; brain development [GO:0007420]; cardiac muscle tissue development [GO:0048738]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; chondrocyte differentiation [GO:0002062]; embryonic skeletal system morphogenesis [GO:0048704]; endochondral ossification [GO:0001958]; extracellular matrix organization [GO:0030198]; negative regulation of amyloid fibril formation [GO:1905907]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell death [GO:0060548]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of endothelial cell proliferation [GO:0001938]; protein localization [GO:0008104]; receptor-mediated endocytosis [GO:0006898]; smoothened signaling pathway [GO:0007224]; tissue development [GO:0009888] GO:0001525; GO:0001938; GO:0001958; GO:0002020; GO:0002062; GO:0005509; GO:0005576; GO:0005604; GO:0005796; GO:0006898; GO:0007162; GO:0007224; GO:0007420; GO:0008022; GO:0008104; GO:0008285; GO:0009887; GO:0009888; GO:0030198; GO:0031012; GO:0048704; GO:0048738; GO:0060351; GO:0060548; GO:0062023; GO:0070052; GO:1905907 22559 XM_044323270.1 0 3 0 17 0 NA NA NA NA NA NA 22560 XR_006396884.1 5 13 19 0 4 NA NA NA NA NA NA 22561 XM_044311014.1 4501 4594 3276 5749 3358 Q7YQK9 1.05e-49 Tetraspanin-7 (Tspan-7) (Transmembrane 4 superfamily member 2) (CD antigen CD231) Pongo pygmaeus (Bornean orangutan) NA GO:0016020 22562 XM_029354285.2 92 0 0 32 6 NA NA NA NA NA NA 22563 XM_029351165.2 1121 1242 764 1228 559 Q63159 5.34e-72 Ubiquinone biosynthesis O-methyltransferase, mitochondrial (3-demethylubiquinol 3-O-methyltransferase) (EC 2.1.1.64) (Polyprenyldihydroxybenzoate methyltransferase) (EC 2.1.1.114) Rattus norvegicus (Rat) glycerol metabolic process [GO:0006071]; methylation [GO:0032259]; regulation of ubiquinone biosynthetic process [GO:0010795]; ubiquinone biosynthetic process [GO:0006744] GO:0004395; GO:0005739; GO:0005743; GO:0006071; GO:0006744; GO:0008168; GO:0008171; GO:0008425; GO:0008689; GO:0010795; GO:0031314; GO:0032259; GO:0110142 22564 XM_029345662.2 0 16 2 14 0 NA NA NA NA NA NA 22565 XM_029340962.2 971 586 255 863 491 Q4KKZ1 1.81e-30 Cilia- and flagella-associated protein 107 Mus musculus (Mouse) NA GO:0005879 22566 XM_044323493.1 0 25 15 43 29 NA NA NA NA NA NA 22567 XM_029358124.2 942 421 404 614 694 NA NA NA NA NA NA 22568 XM_044319180.1 60 1 31 2 164 NA NA NA NA NA NA 22569 XM_044312857.1 1291 1470 755 1503 1455 Q9Y2X7 0 ARF GTPase-activating protein GIT1 (ARF GAP GIT1) (Cool-associated and tyrosine-phosphorylated protein 1) (CAT-1) (CAT1) (G protein-coupled receptor kinase-interactor 1) (GRK-interacting protein 1) (p95-APP1) Homo sapiens (Human) brain development [GO:0007420]; cell redox homeostasis [GO:0045454]; cellular response to lipopolysaccharide [GO:0071222]; ephrin receptor signaling pathway [GO:0048013]; intramembranous ossification [GO:0001957]; locomotory behavior [GO:0007626]; motor learning [GO:0061743]; negative regulation of glycolytic process [GO:0045820]; negative regulation of inflammatory response to wounding [GO:0106015]; negative regulation of interleukin-1 beta production [GO:0032691]; neuron development [GO:0048666]; positive regulation of microtubule nucleation [GO:0090063]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of ARF protein signal transduction [GO:0032012]; regulation of cytokinesis [GO:0032465]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; regulation of synaptic vesicle exocytosis [GO:2000300]; synaptic vesicle recycling [GO:0036465] GO:0001957; GO:0005096; GO:0005739; GO:0005813; GO:0005829; GO:0005925; GO:0007420; GO:0007626; GO:0008277; GO:0014069; GO:0016020; GO:0030027; GO:0031267; GO:0032012; GO:0032465; GO:0032691; GO:0036465; GO:0043005; GO:0043015; GO:0044305; GO:0044877; GO:0045202; GO:0045454; GO:0045820; GO:0046872; GO:0048013; GO:0048666; GO:0061743; GO:0071222; GO:0090063; GO:0097431; GO:0098794; GO:0099171; GO:0106015; GO:2000300 22570 XM_029330403.2 4473 2283 2222 3361 3605 A0A8I3NFE2 1.01e-171 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 (EC 3.1.3.86) (Inositol polyphosphate phosphatase-like protein 1) (INPPL-1) (Protein 51C) (SH2 domain-containing inositol 5'-phosphatase 2) (SH2 domain-containing inositol phosphatase 2) (SHIP-2) Canis lupus familiaris (Dog) (Canis familiaris) actin filament organization [GO:0007015]; endochondral ossification [GO:0001958]; endocytosis [GO:0006897]; glucose metabolic process [GO:0006006]; immune system process [GO:0002376]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; post-embryonic development [GO:0009791]; response to insulin [GO:0032868]; ruffle assembly [GO:0097178] GO:0000922; GO:0001958; GO:0002376; GO:0003779; GO:0005794; GO:0005829; GO:0006006; GO:0006661; GO:0006897; GO:0007015; GO:0008285; GO:0009791; GO:0009925; GO:0010629; GO:0016607; GO:0016791; GO:0017124; GO:0030027; GO:0030175; GO:0032868; GO:0042169; GO:0046856; GO:0097178 22571 XM_044322720.1 0 0 0 103 0 Q8CBF3 2.93e-159 Ephrin type-B receptor 1 (EC 2.7.10.1) Mus musculus (Mouse) angiogenesis [GO:0001525]; axon guidance [GO:0007411]; camera-type eye morphogenesis [GO:0048593]; cell chemotaxis [GO:0060326]; cell-substrate adhesion [GO:0031589]; central nervous system projection neuron axonogenesis [GO:0021952]; cranial nerve development [GO:0021545]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; ephrin receptor signaling pathway [GO:0048013]; establishment of cell polarity [GO:0030010]; hindbrain tangential cell migration [GO:0021934]; immunological synapse formation [GO:0001771]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of satellite cell differentiation [GO:1902725]; negative regulation of skeletal muscle satellite cell proliferation [GO:1902723]; neural precursor cell proliferation [GO:0061351]; neurogenesis [GO:0022008]; optic nerve morphogenesis [GO:0021631]; positive regulation of kinase activity [GO:0033674]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of neuron death [GO:1901214]; retinal ganglion cell axon guidance [GO:0031290]; skeletal muscle satellite cell activation [GO:0014719]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0001525; GO:0001771; GO:0004713; GO:0004714; GO:0005005; GO:0005524; GO:0005737; GO:0005783; GO:0005829; GO:0005886; GO:0007169; GO:0007411; GO:0008046; GO:0014719; GO:0016020; GO:0021545; GO:0021631; GO:0021934; GO:0021952; GO:0022008; GO:0030010; GO:0030424; GO:0030425; GO:0031290; GO:0031589; GO:0031901; GO:0032433; GO:0033674; GO:0043005; GO:0043235; GO:0044877; GO:0045121; GO:0046328; GO:0046777; GO:0048013; GO:0048593; GO:0050804; GO:0050965; GO:0051965; GO:0060326; GO:0060996; GO:0060997; GO:0061351; GO:0070372; GO:0098978; GO:1901214; GO:1902723; GO:1902725 22572 XM_044323451.1 0 0 0 18 0 NA NA NA NA NA NA 22573 XM_044317221.1 1601 1480 740 1088 1078 O35231 9.97e-176 Kinesin-like protein KIFC3 Mus musculus (Mouse) epithelial cell-cell adhesion [GO:0090136]; Golgi organization [GO:0007030]; microtubule-based movement [GO:0007018]; microtubule-based process [GO:0007017]; zonula adherens maintenance [GO:0045218] GO:0005524; GO:0005794; GO:0005813; GO:0005871; GO:0005874; GO:0005915; GO:0007017; GO:0007018; GO:0007030; GO:0008017; GO:0008569; GO:0015630; GO:0030659; GO:0042802; GO:0045218; GO:0090136 22574 XM_044320087.1 143 58 176 62 168 NA NA NA NA NA NA 22575 XM_044327039.1 21 0 3 48 120 NA NA NA NA NA NA 22576 XM_029354547.2 106 254 81 362 197 NA NA NA NA NA NA 22577 XM_044317277.1 12 0 0 0 0 NA NA NA NA NA NA 22578 XR_006397775.1 13 9 9 1 6 NA NA NA NA NA NA 22579 XM_029348343.2 1228 613 570 1009 1099 NA NA NA NA NA NA 22580 XM_044321617.1 148 71 141 191 260 Q5ZM41 1.3e-56 Testis-expressed protein 10 homolog Gallus gallus (Chicken) NA GO:0005634; GO:0005730; GO:0071339 22581 XM_044326028.1 218 205 200 327 346 Q5R539 3.5e-141 Serrate RNA effector molecule homolog (Arsenite-resistance protein 2) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) mRNA processing [GO:0006397]; neuronal stem cell population maintenance [GO:0097150]; primary miRNA processing [GO:0031053]; regulation of DNA-templated transcription [GO:0006355] GO:0003677; GO:0005654; GO:0005737; GO:0006355; GO:0006397; GO:0031053; GO:0097150 22582 XM_029336183.2 69 49 44 48 53 NA NA NA NA NA NA 22583 XM_029355451.2 223 129 0 262 245 Q8UVC3 0 Inversin Gallus gallus (Chicken) Wnt signaling pathway [GO:0016055] GO:0005516; GO:0005737; GO:0005856; GO:0016055 22584 XM_044323984.1 172 220 271 318 525 P35546 1.24e-83 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; anatomical structure morphogenesis [GO:0009653]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006919; GO:0007156; GO:0007158; GO:0007169; GO:0007399; GO:0009410; GO:0009653; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030182; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0098797; GO:2001241 22585 XM_044318938.1 20 0 136 39 130 Q58A42 1.01e-73 Protein DD3-3 Dictyostelium discoideum (Social amoeba) NA GO:0016020 22586 XM_044310539.1 6 0 9 0 35 NA NA NA NA NA NA 22587 XR_003825757.2 197 324 131 257 234 NA NA NA NA NA NA 22588 XM_029333836.2 3365 3548 2383 3911 4045 Q9JJW6 6.06e-45 Aly/REF export factor 2 (Alyref) (RNA and export factor-binding protein 2) Mus musculus (Mouse) mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; regulation of DNA recombination [GO:0000018]; replication fork processing [GO:0031297]; RNA export from nucleus [GO:0006405]; RNA splicing [GO:0008380]; viral mRNA export from host cell nucleus [GO:0046784] GO:0000018; GO:0000346; GO:0000781; GO:0003697; GO:0003723; GO:0003729; GO:0005634; GO:0005737; GO:0006397; GO:0006405; GO:0006406; GO:0008380; GO:0031297; GO:0032786; GO:0035145; GO:0046784; GO:0051028; GO:0062153; GO:0071013 22589 XM_029338276.2 353 236 287 290 432 P84104 7.29e-21 Serine/arginine-rich splicing factor 3 (Pre-mRNA-splicing factor SRP20) (Protein X16) (Splicing factor, arginine/serine-rich 3) Mus musculus (Mouse) cellular response to leukemia inhibitory factor [GO:1990830]; insulin receptor signaling pathway [GO:0008286]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; primary miRNA processing [GO:0031053]; regulation of mRNA splicing, via spliceosome [GO:0048024]; RNA splicing [GO:0008380] GO:0000398; GO:0003723; GO:0005634; GO:0005737; GO:0006406; GO:0008286; GO:0008380; GO:0016607; GO:0031053; GO:0043274; GO:0048024; GO:0070878; GO:1990825; GO:1990830 22590 XM_029338749.2 1407 1332 943 1474 1328 Q9BXT4 5.65e-58 Tudor domain-containing protein 1 (Cancer/testis antigen 41.1) (CT41.1) Homo sapiens (Human) DNA methylation involved in gamete generation [GO:0043046]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; P granule organization [GO:0030719]; piRNA processing [GO:0034587]; RNA-mediated gene silencing [GO:0031047]; spermatogenesis [GO:0007283] GO:0005737; GO:0007281; GO:0007283; GO:0030719; GO:0031047; GO:0034587; GO:0043046; GO:0043186; GO:0046872; GO:0051321; GO:0071546 22591 XM_029338749.2 1407 1332 943 1474 1328 Q9BXT4 1.94e-53 Tudor domain-containing protein 1 (Cancer/testis antigen 41.1) (CT41.1) Homo sapiens (Human) DNA methylation involved in gamete generation [GO:0043046]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; P granule organization [GO:0030719]; piRNA processing [GO:0034587]; RNA-mediated gene silencing [GO:0031047]; spermatogenesis [GO:0007283] GO:0005737; GO:0007281; GO:0007283; GO:0030719; GO:0031047; GO:0034587; GO:0043046; GO:0043186; GO:0046872; GO:0051321; GO:0071546 22592 XM_029338749.2 1407 1332 943 1474 1328 Q9BXT4 3.38e-51 Tudor domain-containing protein 1 (Cancer/testis antigen 41.1) (CT41.1) Homo sapiens (Human) DNA methylation involved in gamete generation [GO:0043046]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; P granule organization [GO:0030719]; piRNA processing [GO:0034587]; RNA-mediated gene silencing [GO:0031047]; spermatogenesis [GO:0007283] GO:0005737; GO:0007281; GO:0007283; GO:0030719; GO:0031047; GO:0034587; GO:0043046; GO:0043186; GO:0046872; GO:0051321; GO:0071546 22593 XM_029338749.2 1407 1332 943 1474 1328 Q9BXT4 4.6e-49 Tudor domain-containing protein 1 (Cancer/testis antigen 41.1) (CT41.1) Homo sapiens (Human) DNA methylation involved in gamete generation [GO:0043046]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; P granule organization [GO:0030719]; piRNA processing [GO:0034587]; RNA-mediated gene silencing [GO:0031047]; spermatogenesis [GO:0007283] GO:0005737; GO:0007281; GO:0007283; GO:0030719; GO:0031047; GO:0034587; GO:0043046; GO:0043186; GO:0046872; GO:0051321; GO:0071546 22594 XM_029338749.2 1407 1332 943 1474 1328 Q9BXT4 3.05e-43 Tudor domain-containing protein 1 (Cancer/testis antigen 41.1) (CT41.1) Homo sapiens (Human) DNA methylation involved in gamete generation [GO:0043046]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; P granule organization [GO:0030719]; piRNA processing [GO:0034587]; RNA-mediated gene silencing [GO:0031047]; spermatogenesis [GO:0007283] GO:0005737; GO:0007281; GO:0007283; GO:0030719; GO:0031047; GO:0034587; GO:0043046; GO:0043186; GO:0046872; GO:0051321; GO:0071546 22595 XM_029338749.2 1407 1332 943 1474 1328 Q9BXT4 1.42e-39 Tudor domain-containing protein 1 (Cancer/testis antigen 41.1) (CT41.1) Homo sapiens (Human) DNA methylation involved in gamete generation [GO:0043046]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; P granule organization [GO:0030719]; piRNA processing [GO:0034587]; RNA-mediated gene silencing [GO:0031047]; spermatogenesis [GO:0007283] GO:0005737; GO:0007281; GO:0007283; GO:0030719; GO:0031047; GO:0034587; GO:0043046; GO:0043186; GO:0046872; GO:0051321; GO:0071546 22596 XM_029338749.2 1407 1332 943 1474 1328 Q9BXT4 1.5e-38 Tudor domain-containing protein 1 (Cancer/testis antigen 41.1) (CT41.1) Homo sapiens (Human) DNA methylation involved in gamete generation [GO:0043046]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; P granule organization [GO:0030719]; piRNA processing [GO:0034587]; RNA-mediated gene silencing [GO:0031047]; spermatogenesis [GO:0007283] GO:0005737; GO:0007281; GO:0007283; GO:0030719; GO:0031047; GO:0034587; GO:0043046; GO:0043186; GO:0046872; GO:0051321; GO:0071546 22597 XM_029338749.2 1407 1332 943 1474 1328 Q9BXT4 4.56e-33 Tudor domain-containing protein 1 (Cancer/testis antigen 41.1) (CT41.1) Homo sapiens (Human) DNA methylation involved in gamete generation [GO:0043046]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; P granule organization [GO:0030719]; piRNA processing [GO:0034587]; RNA-mediated gene silencing [GO:0031047]; spermatogenesis [GO:0007283] GO:0005737; GO:0007281; GO:0007283; GO:0030719; GO:0031047; GO:0034587; GO:0043046; GO:0043186; GO:0046872; GO:0051321; GO:0071546 22598 XM_029338749.2 1407 1332 943 1474 1328 Q9BXT4 1.11e-31 Tudor domain-containing protein 1 (Cancer/testis antigen 41.1) (CT41.1) Homo sapiens (Human) DNA methylation involved in gamete generation [GO:0043046]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; P granule organization [GO:0030719]; piRNA processing [GO:0034587]; RNA-mediated gene silencing [GO:0031047]; spermatogenesis [GO:0007283] GO:0005737; GO:0007281; GO:0007283; GO:0030719; GO:0031047; GO:0034587; GO:0043046; GO:0043186; GO:0046872; GO:0051321; GO:0071546 22599 XM_044317370.1 0 0 0 19 80 Q96AY4 5.81e-49 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22600 XM_044317370.1 0 0 0 19 80 Q96AY4 1.8e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22601 XM_044317370.1 0 0 0 19 80 Q96AY4 1.27e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22602 XM_044317370.1 0 0 0 19 80 Q96AY4 4.15e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22603 XM_044317370.1 0 0 0 19 80 Q96AY4 1.69e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22604 XM_044317370.1 0 0 0 19 80 Q96AY4 3.65e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22605 XM_044317370.1 0 0 0 19 80 Q96AY4 4e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22606 XM_044317370.1 0 0 0 19 80 Q96AY4 4.57e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22607 XM_044317370.1 0 0 0 19 80 Q96AY4 9e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22608 XM_029329608.2 5 99 8 18 25 NA NA NA NA NA NA 22609 XM_029329380.2 0 0 0 85 89 Q8BI21 2.83e-29 E3 ubiquitin-protein ligase RNF38 (EC 2.3.2.27) (RING finger protein 38) (RING-type E3 ubiquitin transferase RNF38) Mus musculus (Mouse) protein ubiquitination [GO:0016567] GO:0005634; GO:0005654; GO:0016567; GO:0036126; GO:0046872; GO:0061630 22610 XM_029349861.2 49 17 6 14 6 Q6NLT8 1.11e-29 NA NA NA NA 22611 XR_003824690.2 7883 11993 5196 8074 4129 P51424 9.66e-24 60S ribosomal protein L39-1 Arabidopsis thaliana (Mouse-ear cress) translation [GO:0006412] GO:0003729; GO:0003735; GO:0005773; GO:0005886; GO:0006412; GO:0022625 22612 XM_044310031.1 67 0 0 0 13 NA NA NA NA NA NA 22613 XM_029328598.2 12 6 16 2 11 NA NA NA NA NA NA 22614 XM_044314769.1 42 0 18 76 78 NA NA NA NA NA NA 22615 XR_006396216.1 1 4 4 3 13 NA NA NA NA NA NA 22616 XR_006394438.1 38 36 9 75 23 NA NA NA NA NA NA 22617 XM_029339541.2 563 358 550 353 801 A8C750 0 Thyroid adenoma-associated protein homolog Canis lupus familiaris (Dog) (Canis familiaris) tRNA methylation [GO:0030488]; tRNA nucleoside ribose methylation [GO:0002128] GO:0002128; GO:0030488 22618 XM_029330676.2 16978 22657 11118 24625 9522 Q0P6D2 2.22e-39 Divergent protein kinase domain 1C (Protein FAM69C) Homo sapiens (Human) NA GO:0005789 22619 XM_044324288.1 0 8 0 37 0 Q76IC6 3.28e-52 Palmitoyltransferase ZDHHC23 (EC 2.3.1.225) (NNOS-interacting DHHC domain-containing protein with dendritic mRNA) (Zinc finger DHHC domain-containing protein 23) (DHHC-23) (zDHHC23) Rattus norvegicus (Rat) peptidyl-L-cysteine S-palmitoylation [GO:0018230]; protein localization to plasma membrane [GO:0072659]; protein palmitoylation [GO:0018345]; protein targeting to membrane [GO:0006612] GO:0000139; GO:0005783; GO:0005794; GO:0006612; GO:0018230; GO:0018345; GO:0019706; GO:0072659 22620 XM_044309194.1 33 15 0 31 18 Q3UQ28 6.66e-32 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 22621 XM_044309194.1 33 15 0 31 18 Q3UQ28 5.75e-27 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 22622 XM_029336180.2 33 221 210 280 351 Q61603 8.2e-66 Glycine receptor subunit alpha-4 Mus musculus (Mouse) chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; neuropeptide signaling pathway [GO:0007218]; regulation of membrane potential [GO:0042391]; response to amino acid [GO:0043200]; signal transduction [GO:0007165]; synaptic transmission, glycinergic [GO:0060012] GO:0004888; GO:0005231; GO:0005886; GO:0007165; GO:0007218; GO:0007268; GO:0016594; GO:0016934; GO:0030425; GO:0030594; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0043200; GO:0043204; GO:0045202; GO:0050877; GO:0060012; GO:0098690; GO:0099634; GO:1902476; GO:1904315 22623 XM_029332135.2 217 85 0 0 178 NA NA NA NA NA NA 22624 XM_044307645.1 1431 920 655 1321 1536 NA NA NA NA NA NA 22625 XM_029339130.2 3039 3492 2343 2744 2227 Q6V289 1.26e-44 Costars family protein ABRACL (ABRA C-terminal-like protein) Coturnix coturnix (Common quail) (Tetrao coturnix) NA NA 22626 XM_044310330.1 177 29 18 239 48 NA NA NA NA NA NA 22627 XM_029354329.2 86 30 16 95 23 NA NA NA NA NA NA 22628 XM_029324960.2 0 0 14 85 96 NA NA NA NA NA NA 22629 XM_044320903.1 280 127 84 180 375 P33174 0 Chromosome-associated kinesin KIF4 (Chromokinesin) Mus musculus (Mouse) microtubule-based movement [GO:0007018]; mitotic cytokinesis [GO:0000281]; mitotic spindle midzone assembly [GO:0051256]; mitotic spindle organization [GO:0007052]; spindle elongation [GO:0051231] GO:0000281; GO:0003677; GO:0003777; GO:0005524; GO:0005654; GO:0005694; GO:0005829; GO:0005874; GO:0005875; GO:0007018; GO:0007052; GO:0008017; GO:0030496; GO:0046872; GO:0051231; GO:0051256; GO:0051536 22630 XM_044313074.1 13 4 1 0 0 P58158 1.22e-80 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 (EC 2.4.1.135) (Beta-1,3-glucuronyltransferase 3) (Glucuronosyltransferase I) (GlcAT-I) (UDP-GlcUA:Gal beta-1,3-Gal-R glucuronyltransferase) (GlcUAT-I) Mus musculus (Mouse) carbohydrate metabolic process [GO:0005975]; chondroitin sulfate proteoglycan biosynthetic process [GO:0050650]; dermatan sulfate proteoglycan biosynthetic process [GO:0050651]; glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; positive regulation of catalytic activity [GO:0043085]; positive regulation of intracellular protein transport [GO:0090316]; protein glycosylation [GO:0006486] GO:0000139; GO:0005794; GO:0005801; GO:0005975; GO:0006024; GO:0006486; GO:0015012; GO:0015018; GO:0015020; GO:0043085; GO:0046872; GO:0050650; GO:0050651; GO:0072542; GO:0090316 22631 XM_044308652.1 177 125 97 87 79 E7FAM5 1.05e-56 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 22632 XM_029344252.2 0 341 139 53 161 Q9NPF2 1.37e-38 Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4S-1) (C4ST-1) (C4ST1) Homo sapiens (Human) apoptotic process [GO:0006915]; carbohydrate biosynthetic process [GO:0016051]; chondrocyte development [GO:0002063]; chondroitin sulfate biosynthetic process [GO:0030206]; developmental growth [GO:0048589]; embryonic digit morphogenesis [GO:0042733]; embryonic viscerocranium morphogenesis [GO:0048703]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; polysaccharide localization [GO:0033037]; post-anal tail morphogenesis [GO:0036342]; post-embryonic development [GO:0009791]; proteoglycan biosynthetic process [GO:0030166]; regulation of cell population proliferation [GO:0042127]; respiratory gaseous exchange by respiratory system [GO:0007585]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0000139; GO:0001537; GO:0001701; GO:0002063; GO:0006915; GO:0007179; GO:0007585; GO:0008146; GO:0009791; GO:0016020; GO:0016051; GO:0030166; GO:0030206; GO:0030512; GO:0033037; GO:0036342; GO:0042127; GO:0042733; GO:0043066; GO:0047756; GO:0048589; GO:0048703; GO:0050659 22633 XM_029348127.2 9 0 0 0 0 Q66GQ5 2.33e-115 Protein REDUCED WALL ACETYLATION 3 (EC 2.3.1.-) Arabidopsis thaliana (Mouse-ear cress) carbohydrate metabolic process [GO:0005975]; plant-type secondary cell wall biogenesis [GO:0009834]; xylan acetylation [GO:1990937]; xylan biosynthetic process [GO:0045492]; xylan metabolic process [GO:0045491]; xyloglucan metabolic process [GO:0010411] GO:0000139; GO:0005794; GO:0005975; GO:0009834; GO:0010411; GO:0016407; GO:0016491; GO:0045491; GO:0045492; GO:1990937 22634 XM_044327653.1 11 2 4 0 1 Q96AY4 2.3e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22635 XR_006394323.1 1199 786 415 849 1360 NA NA NA NA NA NA 22636 XM_044321906.1 2 9 8 26 28 Q9DGD1 4.29e-62 Alpha-1,6-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase (EC 2.4.1.201) (N-acetylglucosaminyltransferase VI) (GnT-VI) Gallus gallus (Chicken) protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0046872; GO:0047253 22637 XM_029328696.2 109 63 18 60 2 NA NA NA NA NA NA 22638 XM_029347639.2 248 249 46 160 209 NA NA NA NA NA NA 22639 XM_029351738.2 566 383 215 516 563 Q0IIF0 2.04e-119 Integrin-linked kinase-associated serine/threonine phosphatase 2C (ILKAP) (EC 3.1.3.16) Bos taurus (Bovine) protein dephosphorylation [GO:0006470] GO:0005634; GO:0005829; GO:0006470; GO:0017018; GO:0046872 22640 XM_044322062.1 38 19 242 125 0 Q7RTR2 3.64e-25 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22641 XM_044322062.1 38 19 242 125 0 Q7RTR2 8.35e-23 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22642 XM_029331354.2 0 7 0 10 5 NA NA NA NA NA NA 22643 XM_029341261.2 28 8 6 26 6 O16025 2.29e-46 Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (AOS) (EC 4.2.1.-) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)] Plexaura homomalla (Black sea rod) arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; lipid oxidation [GO:0034440]; oxylipin biosynthetic process [GO:0031408] GO:0005506; GO:0005737; GO:0006633; GO:0009978; GO:0016020; GO:0019369; GO:0020037; GO:0031408; GO:0034440; GO:0047677 22644 XM_044316814.1 138 68 16 242 29 NA NA NA NA NA NA 22645 XM_044324146.1 68 42 28 29 69 NA NA NA NA NA NA 22646 XM_029333019.2 130 105 310 721 332 Q01970 7.29e-109 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-3) (Phospholipase C-beta-3) (PLC-beta-3) Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186]; lipid catabolic process [GO:0016042]; phosphatidylinositol metabolic process [GO:0046488]; phosphatidylinositol-mediated signaling [GO:0048015]; regulation of systemic arterial blood pressure [GO:0003073] GO:0003073; GO:0004435; GO:0004629; GO:0005509; GO:0005516; GO:0005634; GO:0005829; GO:0007186; GO:0016020; GO:0016042; GO:0032991; GO:0045296; GO:0046488; GO:0048015; GO:0060090; GO:0099524; GO:0140677 22647 XM_044313267.1 11 3 17 16 1 NA NA NA NA NA NA 22648 XM_044313521.1 7 10 1 22 17 A0A0C2SRU0 1.52e-77 Decarboxylase iboD (EC 4.1.1.-) (Ibotenic acid biosynthesis cluster protein D) Amanita muscaria (strain Koide BX008) phospholipid biosynthetic process [GO:0008654] GO:0004609; GO:0008654 22649 XM_044323085.1 0 8 0 0 3 NA NA NA NA NA NA 22650 XM_029330494.2 241 223 277 425 260 P07902 2.68e-155 Galactose-1-phosphate uridylyltransferase (Gal-1-P uridylyltransferase) (EC 2.7.7.12) (UDP-glucose--hexose-1-phosphate uridylyltransferase) Homo sapiens (Human) galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]; UDP-glucose catabolic process [GO:0006258]; UDP-glucose metabolic process [GO:0006011] GO:0005737; GO:0005794; GO:0005829; GO:0006011; GO:0006012; GO:0006258; GO:0008108; GO:0008270; GO:0019388; GO:0033499 22651 XM_029355297.2 54 6 0 24 54 Q5RDZ2 1.61e-86 Lambda-crystallin homolog (EC 1.1.1.45) (L-gulonate 3-dehydrogenase) (Gul3DH) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) fatty acid metabolic process [GO:0006631]; glucuronate catabolic process to xylulose 5-phosphate [GO:0019640] GO:0005829; GO:0006631; GO:0019640; GO:0042803; GO:0050104; GO:0070403 22652 XM_029332659.2 2468 2116 1538 4648 2829 Q32NS4 1.58e-28 E3 ubiquitin-protein ligase arih1 (EC 2.3.2.31) (Protein ariadne-1 homolog) (ARI-1) (RING-type E3 ubiquitin transferase arih1) Xenopus laevis (African clawed frog) protein ubiquitination [GO:0016567] GO:0004842; GO:0005737; GO:0008270; GO:0016567; GO:0016604; GO:0097413 22653 XM_044313158.1 5 19 2 13 18 O02824 9.91e-32 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) Oryctolagus cuniculus (Rabbit) adult heart development [GO:0007512]; cell growth involved in cardiac muscle cell development [GO:0061049]; MAPK cascade [GO:0000165]; multicellular organism aging [GO:0010259]; negative regulation of autophagy [GO:0010507]; negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure [GO:0001985]; neuron-glial cell signaling [GO:0150099]; norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001994]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; pilomotor reflex [GO:0097195]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of the force of heart contraction by epinephrine-norepinephrine [GO:0001997]; regulation of cardiac muscle contraction [GO:0055117]; regulation of vasoconstriction [GO:0019229] GO:0000165; GO:0001985; GO:0001994; GO:0001996; GO:0001997; GO:0004937; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0005901; GO:0007200; GO:0007512; GO:0010259; GO:0010507; GO:0010613; GO:0019229; GO:0031965; GO:0043410; GO:0045987; GO:0046982; GO:0055117; GO:0061049; GO:0097195; GO:0150099; GO:1903997 22654 XR_006397931.1 167 31 36 118 128 NA NA NA NA NA NA 22655 XM_044315847.1 47 65 98 17 194 NA NA NA NA NA NA 22656 XM_044308585.1 60 154 33 76 69 Q14678 2.56e-53 KN motif and ankyrin repeat domain-containing protein 1 (Ankyrin repeat domain-containing protein 15) (Kidney ankyrin repeat-containing protein) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cell population proliferation [GO:0008283]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of cell migration [GO:0030336]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lamellipodium morphogenesis [GO:2000393]; negative regulation of neuron projection development [GO:0010977]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of ruffle assembly [GO:1900028]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025]; podocyte cell migration [GO:0090521]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Wnt signaling pathway [GO:0030177]; positive regulation of wound healing [GO:0090303]; regulation of establishment of cell polarity [GO:2000114]; regulation of Rho protein signal transduction [GO:0035023] GO:0005634; GO:0005737; GO:0005856; GO:0005886; GO:0008013; GO:0008283; GO:0010977; GO:0030036; GO:0030177; GO:0030336; GO:0030837; GO:0032587; GO:0035023; GO:0035024; GO:0046627; GO:0090263; GO:0090303; GO:0090521; GO:1900025; GO:1900028; GO:2000114; GO:2000393 22657 XR_006394106.1 221 146 22 51 76 NA NA NA NA NA NA 22658 XM_044308095.1 234 363 229 396 306 P25439 0 ATP-dependent helicase brm (EC 3.6.4.12) (Homeotic gene regulator) (Protein brahma) Drosophila melanogaster (Fruit fly) axonogenesis [GO:0007409]; cell dedifferentiation [GO:0043697]; chromatin remodeling [GO:0006338]; dendrite guidance [GO:0070983]; dendrite morphogenesis [GO:0048813]; hemocyte proliferation [GO:0035172]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of neuroblast proliferation [GO:0007406]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of innate immune response [GO:0045088]; regulation of neuroblast proliferation [GO:1902692]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription initiation-coupled chromatin remodeling [GO:0045815]; ventral cord development [GO:0007419] GO:0001223; GO:0003677; GO:0004386; GO:0005524; GO:0005634; GO:0005700; GO:0006338; GO:0006357; GO:0007406; GO:0007409; GO:0007419; GO:0007474; GO:0008094; GO:0008586; GO:0008587; GO:0016887; GO:0035060; GO:0035172; GO:0036335; GO:0042393; GO:0043697; GO:0045088; GO:0045815; GO:0045893; GO:0045944; GO:0048813; GO:0070983; GO:0140297; GO:0140566; GO:0140658; GO:1902692; GO:2000134; GO:2000648 22659 XM_029358199.2 1214 472 358 421 540 NA NA NA NA NA NA 22660 XM_029334701.2 81 0 0 68 7 Q9P2P5 0 E3 ubiquitin-protein ligase HECW2 (EC 2.3.2.26) (HECT, C2 and WW domain-containing protein 2) (HECT-type E3 ubiquitin transferase HECW2) (NEDD4-like E3 ubiquitin-protein ligase 2) Homo sapiens (Human) negative regulation of sodium ion transmembrane transporter activity [GO:2000650]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of dendrite morphogenesis [GO:0048814]; regulation of mitotic metaphase/anaphase transition [GO:0030071] GO:0000209; GO:0005737; GO:0016567; GO:0030071; GO:0043161; GO:0048814; GO:0061630; GO:0072686; GO:2000650 22661 XM_029334701.2 81 0 0 68 7 Q9P2P5 1.51e-48 E3 ubiquitin-protein ligase HECW2 (EC 2.3.2.26) (HECT, C2 and WW domain-containing protein 2) (HECT-type E3 ubiquitin transferase HECW2) (NEDD4-like E3 ubiquitin-protein ligase 2) Homo sapiens (Human) negative regulation of sodium ion transmembrane transporter activity [GO:2000650]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of dendrite morphogenesis [GO:0048814]; regulation of mitotic metaphase/anaphase transition [GO:0030071] GO:0000209; GO:0005737; GO:0016567; GO:0030071; GO:0043161; GO:0048814; GO:0061630; GO:0072686; GO:2000650 22662 XM_029346401.2 974 690 334 884 619 Q8BYM7 7.83e-145 Radial spoke head protein 4 homolog A (Radial spoke head-like protein 3) Mus musculus (Mouse) axoneme assembly [GO:0035082]; cilium movement [GO:0003341]; cilium movement involved in cell motility [GO:0060294]; maintenance of ciliary planar beating movement pattern [GO:0120221]; radial spoke assembly [GO:0062177] GO:0001534; GO:0001535; GO:0003341; GO:0005654; GO:0005730; GO:0005929; GO:0005930; GO:0035082; GO:0060294; GO:0062177; GO:0120221 22663 XM_044313606.1 28 5 19 3 9 NA NA NA NA NA NA 22664 XM_044321990.1 6 7 6 7 58 NA NA NA NA NA NA 22665 XM_029349195.2 26 15 0 3 8 NA NA NA NA NA NA 22666 XM_029324324.2 10 3 10 0 36 Q0P9V4 5.02e-22 ATP-dependent DNA helicase pif1 (EC 3.6.4.12) Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) DNA recombination [GO:0006310]; DNA repair [GO:0006281]; telomere maintenance [GO:0000723] GO:0000723; GO:0003677; GO:0003678; GO:0005524; GO:0006281; GO:0006310; GO:0016887 22667 XM_044319464.1 45 25 4 87 2 NA NA NA NA NA NA 22668 XM_044312735.1 14 0 42 0 127 Q8BRH0 1.56e-99 Protein O-mannosyl-transferase TMTC3 (EC 2.4.1.109) (Transmembrane and TPR repeat-containing protein 3) Mus musculus (Mouse) bud outgrowth involved in lung branching [GO:0060447]; cell differentiation [GO:0030154]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; muscle cell development [GO:0055001]; positive regulation of proteasomal protein catabolic process [GO:1901800]; post-embryonic development [GO:0009791]; protein O-linked mannosylation [GO:0035269]; regulation of gene expression [GO:0010468]; response to endoplasmic reticulum stress [GO:0034976] GO:0000030; GO:0004169; GO:0005783; GO:0009791; GO:0010468; GO:0016020; GO:0030154; GO:0030324; GO:0034976; GO:0035269; GO:0048286; GO:0055001; GO:0060447; GO:1901800 22669 XM_029340735.2 181 143 73 18 143 Q05973 0 Sodium channel protein 1 brain (Sodium channel protein I brain) Heterololigo bleekeri (Spear squid) (Loligo bleekeri) regulation of ion transmembrane transport [GO:0034765] GO:0001518; GO:0005244; GO:0005248; GO:0034765 22670 XM_029340735.2 181 143 73 18 143 Q05973 6.01e-82 Sodium channel protein 1 brain (Sodium channel protein I brain) Heterololigo bleekeri (Spear squid) (Loligo bleekeri) regulation of ion transmembrane transport [GO:0034765] GO:0001518; GO:0005244; GO:0005248; GO:0034765 22671 XR_006394508.1 15 21 6 0 3 NA NA NA NA NA NA 22672 XM_044316251.1 38 7 0 15 0 Q95JD5 2.69e-52 Sulfotransferase 1B1 (ST1B1) (cSULT1B1) (EC 2.8.2.1) (Sulfotransferase family cytosolic 1B member 1) Canis lupus familiaris (Dog) (Canis familiaris) 3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; epithelial cell differentiation [GO:0030855]; ethanol catabolic process [GO:0006068]; flavonoid metabolic process [GO:0009812]; sulfation [GO:0051923]; thyroid hormone metabolic process [GO:0042403]; xenobiotic metabolic process [GO:0006805] GO:0004062; GO:0005737; GO:0006068; GO:0006805; GO:0008146; GO:0009812; GO:0030855; GO:0042403; GO:0050427; GO:0051923 22673 XM_044326248.1 7 0 4 0 6 NA NA NA NA NA NA 22674 XM_044321341.1 4 0 3 5 31 NA NA NA NA NA NA 22675 XM_029358173.2 99 102 0 2 27 Q6REY9 1.43e-96 Rho GTPase-activating protein 20 (RA and RhoGAP domain-containing protein) (RARhoGAP) (Rho-type GTPase-activating protein 20) Rattus norvegicus (Rat) regulation of Rho protein signal transduction [GO:0035023]; signal transduction [GO:0007165] GO:0005096; GO:0007165; GO:0031267; GO:0035023 22676 XM_044307620.1 86 9 16 27 61 NA NA NA NA NA NA 22677 XM_044326473.1 244 27 0 22 108 Q5IS99 1.67e-50 Caspase-3 (CASP-3) (EC 3.4.22.56) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12] Saimiri boliviensis boliviensis (Bolivian squirrel monkey) cellular response to staurosporine [GO:0072734]; erythrocyte differentiation [GO:0030218]; intracellular signal transduction [GO:0035556]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of amyloid-beta formation [GO:1902004]; proteolysis [GO:0006508]; regulation of protein stability [GO:0031647] GO:0004175; GO:0005634; GO:0005829; GO:0006508; GO:0030218; GO:0031647; GO:0035556; GO:0048011; GO:0072734; GO:0097153; GO:0097199; GO:0097200; GO:1902004 22678 XM_044322253.1 18 0 0 0 20 NA NA NA NA NA NA 22679 XM_029342940.2 104 103 24 245 66 NA NA NA NA NA NA 22680 XM_044322826.1 117 106 70 79 102 NA NA NA NA NA NA 22681 XM_029346120.2 1645 651 1383 1152 1884 P18074 0 General transcription and DNA repair factor IIH helicase subunit XPD (TFIIH subunit XPD) (EC 3.6.4.12) (Basic transcription factor 2 80 kDa subunit) (BTF2 p80) (CXPD) (DNA excision repair protein ERCC-2) (DNA repair protein complementing XP-D cells) (TFIIH basal transcription factor complex 80 kDa subunit) (TFIIH 80 kDa subunit) (TFIIH p80) (Xeroderma pigmentosum group D-complementing protein) Homo sapiens (Human) aging [GO:0007568]; apoptotic process [GO:0006915]; bone mineralization [GO:0030282]; central nervous system myelin formation [GO:0032289]; chromosome segregation [GO:0007059]; embryonic cleavage [GO:0040016]; erythrocyte maturation [GO:0043249]; extracellular matrix organization [GO:0030198]; hair cell differentiation [GO:0035315]; hair follicle maturation [GO:0048820]; hematopoietic stem cell differentiation [GO:0060218]; hematopoietic stem cell proliferation [GO:0071425]; in utero embryonic development [GO:0001701]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; multicellular organism growth [GO:0035264]; nucleotide-excision repair [GO:0006289]; positive regulation of DNA binding [GO:0043388]; positive regulation of mitotic recombination [GO:0045951]; post-embryonic development [GO:0009791]; regulation of mitotic cell cycle phase transition [GO:1901990]; response to oxidative stress [GO:0006979]; spinal cord development [GO:0021510]; transcription by RNA polymerase II [GO:0006366]; transcription elongation by RNA polymerase I [GO:0006362]; transcription-coupled nucleotide-excision repair [GO:0006283]; UV protection [GO:0009650] GO:0000439; GO:0000462; GO:0001701; GO:0003678; GO:0003684; GO:0005524; GO:0005634; GO:0005654; GO:0005669; GO:0005675; GO:0005737; GO:0005819; GO:0005829; GO:0006283; GO:0006289; GO:0006362; GO:0006366; GO:0006915; GO:0006979; GO:0007059; GO:0007568; GO:0008022; GO:0009650; GO:0009791; GO:0016887; GO:0021510; GO:0030198; GO:0030282; GO:0030674; GO:0032289; GO:0035264; GO:0035315; GO:0040016; GO:0043139; GO:0043249; GO:0043388; GO:0045951; GO:0046872; GO:0047485; GO:0048820; GO:0051539; GO:0060218; GO:0070516; GO:0071425; GO:0071817; GO:1901990 22682 XM_029338529.2 193 207 135 216 225 O14735 1.15e-81 CDP-diacylglycerol--inositol 3-phosphatidyltransferase (EC 2.7.8.11) (Phosphatidylinositol synthase) (PI synthase) (PtdIns synthase) Homo sapiens (Human) CDP-diacylglycerol metabolic process [GO:0046341]; phosphatidylinositol biosynthetic process [GO:0006661] GO:0003881; GO:0005789; GO:0005794; GO:0005886; GO:0006661; GO:0016020; GO:0019992; GO:0030145; GO:0030246; GO:0043178; GO:0046341 22683 XM_029357797.2 0 0 0 0 11 Q9EQD2 3.43e-46 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 22684 XM_044315978.1 0 0 6 0 1 NA NA NA NA NA NA 22685 XM_044313153.1 160 106 102 109 145 NA NA NA NA NA NA 22686 XR_006395834.1 29 13 21 30 15 NA NA NA NA NA NA 22687 XM_044313369.1 2 9 0 0 18 Q708S4 2.34e-54 Acid-sensing ion channel 4-A (ASIC4-A) (Acid-sensing ion channel 4.1) (Amiloride-sensitive cation channel 4-A) (ZASIC4.1) Danio rerio (Zebrafish) (Brachydanio rerio) sodium ion transmembrane transport [GO:0035725] GO:0005248; GO:0005261; GO:0005886; GO:0015280; GO:0035725; GO:0045177 22688 XM_029356057.2 11310 11117 7798 7483 6455 P26990 2.12e-107 ADP-ribosylation factor 6 (EC 3.6.5.2) Gallus gallus (Chicken) cell differentiation [GO:0030154]; cortical actin cytoskeleton organization [GO:0030866]; endocytic recycling [GO:0032456]; erythrocyte apoptotic process [GO:1902217]; establishment of epithelial cell polarity [GO:0090162]; hepatocyte apoptotic process [GO:0097284]; intracellular protein transport [GO:0006886]; liver development [GO:0001889]; negative regulation of protein localization to cell surface [GO:2000009]; nervous system development [GO:0007399]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of focal adhesion disassembly [GO:0120183]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein secretion [GO:0050714]; protein localization to cell surface [GO:0034394]; protein localization to endosome [GO:0036010]; regulation of dendritic spine development [GO:0060998]; regulation of filopodium assembly [GO:0051489]; regulation of neuron projection development [GO:0010975]; regulation of Rac protein signal transduction [GO:0035020]; ruffle assembly [GO:0097178]; vesicle-mediated transport [GO:0016192] GO:0001726; GO:0001889; GO:0003925; GO:0005525; GO:0005737; GO:0005768; GO:0005829; GO:0005886; GO:0005938; GO:0006886; GO:0007399; GO:0010975; GO:0016192; GO:0019003; GO:0030139; GO:0030154; GO:0030838; GO:0030866; GO:0031527; GO:0031996; GO:0032154; GO:0032456; GO:0032587; GO:0034394; GO:0035020; GO:0036010; GO:0047485; GO:0050714; GO:0051489; GO:0051549; GO:0055038; GO:0060998; GO:0090162; GO:0090543; GO:0097178; GO:0097284; GO:0120183; GO:1902217; GO:1903078; GO:2000009 22689 XM_029356057.2 11310 11117 7798 7483 6455 P26990 7.99e-105 ADP-ribosylation factor 6 (EC 3.6.5.2) Gallus gallus (Chicken) cell differentiation [GO:0030154]; cortical actin cytoskeleton organization [GO:0030866]; endocytic recycling [GO:0032456]; erythrocyte apoptotic process [GO:1902217]; establishment of epithelial cell polarity [GO:0090162]; hepatocyte apoptotic process [GO:0097284]; intracellular protein transport [GO:0006886]; liver development [GO:0001889]; negative regulation of protein localization to cell surface [GO:2000009]; nervous system development [GO:0007399]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of focal adhesion disassembly [GO:0120183]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein secretion [GO:0050714]; protein localization to cell surface [GO:0034394]; protein localization to endosome [GO:0036010]; regulation of dendritic spine development [GO:0060998]; regulation of filopodium assembly [GO:0051489]; regulation of neuron projection development [GO:0010975]; regulation of Rac protein signal transduction [GO:0035020]; ruffle assembly [GO:0097178]; vesicle-mediated transport [GO:0016192] GO:0001726; GO:0001889; GO:0003925; GO:0005525; GO:0005737; GO:0005768; GO:0005829; GO:0005886; GO:0005938; GO:0006886; GO:0007399; GO:0010975; GO:0016192; GO:0019003; GO:0030139; GO:0030154; GO:0030838; GO:0030866; GO:0031527; GO:0031996; GO:0032154; GO:0032456; GO:0032587; GO:0034394; GO:0035020; GO:0036010; GO:0047485; GO:0050714; GO:0051489; GO:0051549; GO:0055038; GO:0060998; GO:0090162; GO:0090543; GO:0097178; GO:0097284; GO:0120183; GO:1902217; GO:1903078; GO:2000009 22690 XM_044322717.1 14 22 27 17 37 NA NA NA NA NA NA 22691 XM_029355104.2 107 549 208 409 302 NA NA NA NA NA NA 22692 XM_029336567.2 265 37 44 72 15 P63079 4e-82 Gamma-aminobutyric acid receptor subunit beta-3 (GABA(A) receptor subunit beta-3) Rattus norvegicus (Rat) brain development [GO:0007420]; cellular response to histamine [GO:0071420]; cellular response to zinc ion [GO:0071294]; cerebellum development [GO:0021549]; chemical synaptic transmission [GO:0007268]; chemical synaptic transmission, postsynaptic [GO:0099565]; chloride transmembrane transport [GO:1902476]; circadian sleep/wake cycle, REM sleep [GO:0042747]; cochlea development [GO:0090102]; exploration behavior [GO:0035640]; gamma-aminobutyric acid signaling pathway [GO:0007214]; hard palate development [GO:0060022]; inhibitory postsynaptic potential [GO:0060080]; inhibitory synapse assembly [GO:1904862]; inner ear receptor cell development [GO:0060119]; innervation [GO:0060384]; ion transmembrane transport [GO:0034220]; learning [GO:0007612]; memory [GO:0007613]; motor behavior [GO:0061744]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; nervous system development [GO:0007399]; nervous system process [GO:0050877]; neuron development [GO:0048666]; regulation of membrane potential [GO:0042391]; regulation of neuron apoptotic process [GO:0043523]; regulation of postsynaptic membrane potential [GO:0060078]; reproductive behavior [GO:0019098]; response to anesthetic [GO:0072347]; response to xenobiotic stimulus [GO:0009410]; roof of mouth development [GO:0060021]; sensory perception of sound [GO:0007605]; signal transduction [GO:0007165]; social behavior [GO:0035176]; synaptic transmission, GABAergic [GO:0051932] GO:0004890; GO:0005216; GO:0005231; GO:0005254; GO:0005886; GO:0007165; GO:0007214; GO:0007268; GO:0007399; GO:0007420; GO:0007605; GO:0007612; GO:0007613; GO:0009410; GO:0009986; GO:0019098; GO:0021549; GO:0022851; GO:0030594; GO:0030659; GO:0034220; GO:0034707; GO:0035176; GO:0035612; GO:0035640; GO:0042391; GO:0042747; GO:0042802; GO:0043005; GO:0043195; GO:0043523; GO:0043524; GO:0045202; GO:0045211; GO:0048666; GO:0050877; GO:0051932; GO:0060021; GO:0060022; GO:0060077; GO:0060078; GO:0060080; GO:0060119; GO:0060384; GO:0061744; GO:0071294; GO:0071420; GO:0072347; GO:0090102; GO:0098982; GO:0099565; GO:0099634; GO:1901215; GO:1902476; GO:1902711; GO:1904315; GO:1904862 22693 XM_044306777.1 10 0 0 6 34 P0DP43 4.67e-39 Cation channel sperm-associated auxiliary subunit epsilon (CatSper-epsilon) (CatSperepsilon) (C1orf101-like protein) Mus musculus (Mouse) flagellated sperm motility [GO:0030317]; sperm capacitation [GO:0048240] GO:0030317; GO:0036128; GO:0048240; GO:0097228 22694 XM_029329484.2 257 10 72 401 186 Q5J316 1.63e-103 Solute carrier family 2, facilitated glucose transporter member 12 (Glucose transporter type 12) (GLUT-12) Bos taurus (Bovine) carbohydrate transport [GO:0008643] GO:0005886; GO:0008643; GO:0012505; GO:0022857; GO:0048471 22695 XM_044320038.1 6 11 4 2 0 NA NA NA NA NA NA 22696 XM_029343252.2 1519 986 904 1079 1336 Q7TSH2 0 Phosphorylase b kinase regulatory subunit beta (Phosphorylase kinase subunit beta) Mus musculus (Mouse) glycogen metabolic process [GO:0005977]; protein phosphorylation [GO:0006468] GO:0005516; GO:0005886; GO:0005964; GO:0005977; GO:0006468 22697 XM_044307734.1 1 8 0 4 0 NA NA NA NA NA NA 22698 XR_006393612.1 0 1 0 43 65 NA NA NA NA NA NA 22699 XM_029351360.2 412 585 178 336 650 Q63ZU0 4.12e-109 Adenosine deaminase (EC 3.5.4.4) (Adenosine aminohydrolase) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) adenosine catabolic process [GO:0006154]; inosine biosynthetic process [GO:0046103]; nucleotide metabolic process [GO:0009117]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168] GO:0004000; GO:0005764; GO:0005886; GO:0006154; GO:0008270; GO:0009117; GO:0009168; GO:0046103; GO:0046936; GO:0060205; GO:0070161 22700 XM_029355123.2 1 0 33 0 30 P10394 2.29e-34 Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 22701 XM_044316299.1 0 0 28 1 0 NA NA NA NA NA NA 22702 XM_029327139.2 24 78 6 36 56 Q9H4G4 2.85e-21 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Homo sapiens (Human) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070062; GO:0070374 22703 XM_029328526.2 1003 1055 529 863 601 A0A8I3S9V6 9.87e-50 GEL complex subunit OPTI (Obligate partner of TMCO1 insertase) (Rab5-interacting protein) (RIP5) (Respirasome Complex Assembly Factor 1) (RCAF1) Canis lupus familiaris (Dog) (Canis familiaris) mitochondrial respirasome assembly [GO:0097250] GO:0016020; GO:0097250 22704 XR_006392198.1 1131 779 826 1026 996 Q9HAB8 8.5e-77 Phosphopantothenate--cysteine ligase (EC 6.3.2.51) (Phosphopantothenoylcysteine synthetase) (PPC synthetase) Homo sapiens (Human) acetyl-CoA biosynthetic process [GO:0006085]; coenzyme A biosynthetic process [GO:0015937]; heart process [GO:0003015] GO:0003015; GO:0004632; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006085; GO:0015937; GO:0042802; GO:0042803 22705 XM_044311264.1 0 14 39 20 33 Q9VBW3 4.23e-63 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 22706 XR_003825734.2 71 21 25 60 29 NA NA NA NA NA NA 22707 XM_044321252.1 88 14 189 21 683 P35858 8.61e-39 Insulin-like growth factor-binding protein complex acid labile subunit (ALS) Homo sapiens (Human) cell adhesion [GO:0007155]; signal transduction [GO:0007165] GO:0005520; GO:0005576; GO:0005615; GO:0007155; GO:0007165; GO:0031012; GO:0042567; GO:0070062 22708 XM_044321252.1 88 14 189 21 683 P35858 2.9e-27 Insulin-like growth factor-binding protein complex acid labile subunit (ALS) Homo sapiens (Human) cell adhesion [GO:0007155]; signal transduction [GO:0007165] GO:0005520; GO:0005576; GO:0005615; GO:0007155; GO:0007165; GO:0031012; GO:0042567; GO:0070062 22709 XM_044321252.1 88 14 189 21 683 P35858 4.57e-26 Insulin-like growth factor-binding protein complex acid labile subunit (ALS) Homo sapiens (Human) cell adhesion [GO:0007155]; signal transduction [GO:0007165] GO:0005520; GO:0005576; GO:0005615; GO:0007155; GO:0007165; GO:0031012; GO:0042567; GO:0070062 22710 XM_044321252.1 88 14 189 21 683 P35858 1.85e-21 Insulin-like growth factor-binding protein complex acid labile subunit (ALS) Homo sapiens (Human) cell adhesion [GO:0007155]; signal transduction [GO:0007165] GO:0005520; GO:0005576; GO:0005615; GO:0007155; GO:0007165; GO:0031012; GO:0042567; GO:0070062 22711 XM_044328638.1 112 42 0 156 48 NA NA NA NA NA NA 22712 XM_044322855.1 382 317 182 384 250 Q3USZ8 3.1e-41 Divergent protein kinase domain 2A (Deleted in autism protein 1 homolog) (Golgi Protein of 49 kDa) (GoPro49) (Hypoxia and AKT-induced stem cell factor) (HASF) Mus musculus (Mouse) cardiac muscle cell proliferation [GO:0060038]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; positive regulation of protein kinase C activity [GO:1900020]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; vesicle targeting, to, from or within Golgi [GO:0048199] GO:0000139; GO:0005576; GO:0005615; GO:0014066; GO:0030126; GO:0030137; GO:0034392; GO:0048199; GO:0060038; GO:1900020 22713 XM_044313922.1 181 126 78 231 106 NA NA NA NA NA NA 22714 XM_044318068.1 1437 951 656 1122 940 Q5EAJ7 0 Major vault protein (MVP) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005634; GO:0005737; GO:1990904 22715 XR_003827937.2 143 139 119 84 142 NA NA NA NA NA NA 22716 XR_003824058.2 9 8 2 33 3 NA NA NA NA NA NA 22717 XR_006393165.1 35 0 0 40 0 NA NA NA NA NA NA 22718 XM_044322689.1 10 1 13 0 9 NA NA NA NA NA NA 22719 XM_044329005.1 812 264 548 405 552 Q8BJ34 4.51e-87 Meiosis regulator and mRNA stability factor 1 (Limkain-b1) (Meiosis arrest female protein 1) Mus musculus (Mouse) double-strand break repair [GO:0006302]; female meiotic nuclear division [GO:0007143]; oogenesis [GO:0048477]; regulation of gene expression [GO:0010468] GO:0004540; GO:0005737; GO:0005777; GO:0005794; GO:0006302; GO:0007143; GO:0010468; GO:0043231; GO:0048477; GO:1903231; GO:1905762 22720 XM_044329005.1 812 264 548 405 552 Q8BJ34 4.31e-44 Meiosis regulator and mRNA stability factor 1 (Limkain-b1) (Meiosis arrest female protein 1) Mus musculus (Mouse) double-strand break repair [GO:0006302]; female meiotic nuclear division [GO:0007143]; oogenesis [GO:0048477]; regulation of gene expression [GO:0010468] GO:0004540; GO:0005737; GO:0005777; GO:0005794; GO:0006302; GO:0007143; GO:0010468; GO:0043231; GO:0048477; GO:1903231; GO:1905762 22721 XM_044329005.1 812 264 548 405 552 Q8BJ34 1.73e-34 Meiosis regulator and mRNA stability factor 1 (Limkain-b1) (Meiosis arrest female protein 1) Mus musculus (Mouse) double-strand break repair [GO:0006302]; female meiotic nuclear division [GO:0007143]; oogenesis [GO:0048477]; regulation of gene expression [GO:0010468] GO:0004540; GO:0005737; GO:0005777; GO:0005794; GO:0006302; GO:0007143; GO:0010468; GO:0043231; GO:0048477; GO:1903231; GO:1905762 22722 XM_044329005.1 812 264 548 405 552 Q8BJ34 3.48e-27 Meiosis regulator and mRNA stability factor 1 (Limkain-b1) (Meiosis arrest female protein 1) Mus musculus (Mouse) double-strand break repair [GO:0006302]; female meiotic nuclear division [GO:0007143]; oogenesis [GO:0048477]; regulation of gene expression [GO:0010468] GO:0004540; GO:0005737; GO:0005777; GO:0005794; GO:0006302; GO:0007143; GO:0010468; GO:0043231; GO:0048477; GO:1903231; GO:1905762 22723 XM_029326994.2 3167 3876 1955 6004 1715 Q6P1V8 0 Zygotic DNA replication licensing factor mcm6 (EC 3.6.4.12) (Zygotic minichromosome maintenance protein 6) (zMCM6) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell cycle [GO:0007049]; DNA replication initiation [GO:0006270] GO:0003677; GO:0003678; GO:0005524; GO:0005634; GO:0006270; GO:0007049; GO:0016887; GO:0042555; GO:0046872 22724 XM_029358553.2 2106 1455 1645 2516 1815 Q7Z3J2 0 VPS35 endosomal protein-sorting factor-like (Esophageal cancer-associated protein) Homo sapiens (Human) endocytic recycling [GO:0032456]; Golgi to plasma membrane transport [GO:0006893]; protein transport [GO:0015031] GO:0005768; GO:0005886; GO:0006893; GO:0015031; GO:0032456; GO:0101003 22725 XR_003825278.2 1313 1021 757 1016 1131 NA NA NA NA NA NA 22726 XM_044319116.1 4 0 44 0 0 NA NA NA NA NA NA 22727 XM_029331923.2 171 105 43 112 101 Q8WV92 5.91e-89 MIT domain-containing protein 1 Homo sapiens (Human) midbody abscission [GO:0061952]; mitotic cytokinesis [GO:0000281]; negative regulation of protein binding [GO:0032091] GO:0000281; GO:0019898; GO:0019904; GO:0030496; GO:0031902; GO:0032091; GO:0035091; GO:0042802; GO:0043231; GO:0061952; GO:0070062 22728 XM_029340819.2 377 640 350 1067 1816 Q8K3C3 7.99e-67 Protein LZIC (Leucine zipper and CTNNBIP1 domain-containing protein) (Leucine zipper and ICAT homologous domain-containing protein) Mus musculus (Mouse) negative regulation of Wnt signaling pathway [GO:0030178] GO:0008013; GO:0030178 22729 XR_006393280.1 506 144 295 425 388 NA NA NA NA NA NA 22730 XR_003827295.2 8 0 0 9 11 P08537 1.63e-42 Tubulin alpha chain (EC 3.6.5.-) [Cleaved into: Detyrosinated tubulin alpha chain] Xenopus laevis (African clawed frog) microtubule-based process [GO:0007017] GO:0005200; GO:0005525; GO:0005737; GO:0005874; GO:0007017; GO:0016787; GO:0046872 22731 XM_029343802.2 865 764 615 964 1505 Q969G6 3.25e-67 Riboflavin kinase (EC 2.7.1.26) (ATP:riboflavin 5'-phosphotransferase) (Flavokinase) Homo sapiens (Human) apoptotic process [GO:0006915]; FMN biosynthetic process [GO:0009398]; phosphorylation [GO:0016310]; positive regulation of NAD(P)H oxidase activity [GO:0033864]; reactive oxygen species metabolic process [GO:0072593]; riboflavin biosynthetic process [GO:0009231]; riboflavin metabolic process [GO:0006771] GO:0005524; GO:0005737; GO:0005739; GO:0005829; GO:0006771; GO:0006915; GO:0008531; GO:0009231; GO:0009398; GO:0016310; GO:0033864; GO:0046872; GO:0072593 22732 XM_044311797.1 0 0 115 79 0 NA NA NA NA NA NA 22733 XR_006394552.1 40 7 3 0 6 NA NA NA NA NA NA 22734 XM_044320310.1 14 18 8 1 0 O70244 6.15e-70 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 22735 XM_044320310.1 14 18 8 1 0 O70244 2.23e-66 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 22736 XM_044320310.1 14 18 8 1 0 O70244 1.69e-63 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 22737 XM_044320310.1 14 18 8 1 0 O70244 1.25e-60 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 22738 XM_044320310.1 14 18 8 1 0 O70244 5.79e-59 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 22739 XM_044320310.1 14 18 8 1 0 O70244 6.84e-50 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 22740 XM_044320310.1 14 18 8 1 0 O70244 1.01e-48 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 22741 XM_044320310.1 14 18 8 1 0 O70244 2.76e-47 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 22742 XR_003824785.2 9 11 19 16 24 NA NA NA NA NA NA 22743 XR_006392899.1 41 2 25 5 151 NA NA NA NA NA NA 22744 XM_044312501.1 20 64 54 44 14 NA NA NA NA NA NA 22745 XM_029341855.2 1 0 0 128 0 NA NA NA NA NA NA 22746 XM_044319704.1 39 8 21 102 27 Q09575 1.13e-31 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 22747 XR_006392491.1 13 8 11 33 8 NA NA NA NA NA NA 22748 XR_003826351.2 47 43 17 86 51 NA NA NA NA NA NA 22749 XM_044307604.1 281 219 100 121 63 Q9Y256 3.58e-72 CAAX prenyl protease 2 (EC 3.4.-.-) (Farnesylated proteins-converting enzyme 2) (FACE-2) (Prenyl protein-specific endoprotease 2) (RCE1 homolog) (hRCE1) Homo sapiens (Human) CAAX-box protein processing [GO:0071586]; MAPK cascade [GO:0000165]; protein prenylation [GO:0018342] GO:0000165; GO:0004175; GO:0004197; GO:0004222; GO:0005789; GO:0005829; GO:0005886; GO:0008238; GO:0016020; GO:0018342; GO:0071586 22750 XM_029333484.2 457 175 138 227 240 NA NA NA NA NA NA 22751 XR_003826130.2 54 11 37 47 45 NA NA NA NA NA NA 22752 XM_044323991.1 2373 2315 1393 2448 2297 P52594 5.05e-66 Arf-GAP domain and FG repeat-containing protein 1 (HIV-1 Rev-binding protein) (Nucleoporin-like protein RIP) (Rev-interacting protein) (Rev/Rex activation domain-binding protein) Homo sapiens (Human) acrosome assembly [GO:0001675]; intermediate filament organization [GO:0045109]; mRNA export from nucleus [GO:0006406]; spermatid nucleus differentiation [GO:0007289] GO:0001675; GO:0003677; GO:0003723; GO:0005096; GO:0005643; GO:0005737; GO:0005829; GO:0006406; GO:0007289; GO:0031410; GO:0043231; GO:0045109; GO:0046872 22753 XM_029353069.2 7 8 11 14 39 NA NA NA NA NA NA 22754 XM_029357320.2 467 0 66 74 172 Q96CG8 7.6e-41 Collagen triple helix repeat-containing protein 1 Homo sapiens (Human) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005576; GO:0005581; GO:0005615; GO:0016477; GO:0016528; GO:0017147; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0062023; GO:0090090; GO:0090103; GO:0090177 22755 XM_044310687.1 21 0 0 8 0 Q4R3J0 1.26e-123 RNA 3'-terminal phosphate cyclase (RNA cyclase) (RNA-3'-phosphate cyclase) (EC 6.5.1.4) (RNA terminal phosphate cyclase domain-containing protein 1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) RNA processing [GO:0006396] GO:0003963; GO:0005524; GO:0005654; GO:0006396 22756 XR_006398159.1 3113 1617 127 1854 299 NA NA NA NA NA NA 22757 XM_044306989.1 20 20 6 81 41 P35447 3.88e-22 Spondin-1 (F-spondin) Xenopus laevis (African clawed frog) cell adhesion [GO:0007155] GO:0005576; GO:0007155; GO:0046872 22758 XM_029323738.2 440 215 238 559 396 Q13485 1.04e-50 Mothers against decapentaplegic homolog 4 (MAD homolog 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4) (SMAD family member 4) (SMAD 4) (Smad4) (hSMAD4) Homo sapiens (Human) activin receptor signaling pathway [GO:0032924]; adrenal gland development [GO:0030325]; aging [GO:0007568]; anatomical structure morphogenesis [GO:0009653]; atrioventricular canal development [GO:0036302]; atrioventricular valve formation [GO:0003190]; axon guidance [GO:0007411]; BMP signaling pathway [GO:0030509]; brainstem development [GO:0003360]; branching involved in ureteric bud morphogenesis [GO:0001658]; cardiac conduction system development [GO:0003161]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular iron ion homeostasis [GO:0006879]; cellular response to BMP stimulus [GO:0071773]; cellular response to glucose stimulus [GO:0071333]; developmental growth [GO:0048589]; DNA-templated transcription [GO:0006351]; embryonic digit morphogenesis [GO:0042733]; endocardial cell differentiation [GO:0060956]; endoderm development [GO:0007492]; endothelial cell activation [GO:0042118]; epithelial cell migration [GO:0010631]; epithelial to mesenchymal transition [GO:0001837]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; ERK1 and ERK2 cascade [GO:0070371]; female gonad morphogenesis [GO:0061040]; formation of anatomical boundary [GO:0048859]; gastrulation with mouth forming second [GO:0001702]; in utero embryonic development [GO:0001701]; interleukin-6-mediated signaling pathway [GO:0070102]; intracellular signal transduction [GO:0035556]; left ventricular cardiac muscle tissue morphogenesis [GO:0003220]; mesoderm development [GO:0007498]; metanephric mesenchyme morphogenesis [GO:0072133]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of cardiac myofibril assembly [GO:1905305]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nephrogenic mesenchyme morphogenesis [GO:0072134]; neural crest cell differentiation [GO:0014033]; neuron fate commitment [GO:0048663]; osteoblast differentiation [GO:0001649]; outflow tract septum morphogenesis [GO:0003148]; ovarian follicle development [GO:0001541]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell proliferation involved in heart valve morphogenesis [GO:0003251]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of follicle-stimulating hormone secretion [GO:0046881]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of histone H3-K9 acetylation [GO:2000617]; positive regulation of luteinizing hormone secretion [GO:0033686]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; regulation of binding [GO:0051098]; regulation of hair follicle development [GO:0051797]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; regulation of transforming growth factor beta2 production [GO:0032909]; response to hypoxia [GO:0001666]; response to transforming growth factor beta [GO:0071559]; sebaceous gland development [GO:0048733]; secondary palate development [GO:0062009]; seminiferous tubule development [GO:0072520]; single fertilization [GO:0007338]; SMAD protein complex assembly [GO:0007183]; SMAD protein signal transduction [GO:0060395]; somite rostral/caudal axis specification [GO:0032525]; spermatogenesis [GO:0007283]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]; uterus development [GO:0060065]; ventricular septum morphogenesis [GO:0060412]; wound healing [GO:0042060] GO:0000122; GO:0000785; GO:0000976; GO:0000978; GO:0000981; GO:0001223; GO:0001228; GO:0001541; GO:0001649; GO:0001658; GO:0001666; GO:0001701; GO:0001702; GO:0001837; GO:0003148; GO:0003161; GO:0003190; GO:0003198; GO:0003220; GO:0003251; GO:0003360; GO:0003682; GO:0005518; GO:0005634; GO:0005654; GO:0005667; GO:0005737; GO:0005813; GO:0005829; GO:0006351; GO:0006366; GO:0006879; GO:0007179; GO:0007183; GO:0007283; GO:0007338; GO:0007411; GO:0007492; GO:0007498; GO:0007568; GO:0008283; GO:0008285; GO:0009653; GO:0010614; GO:0010631; GO:0010666; GO:0010718; GO:0010862; GO:0014033; GO:0017015; GO:0030154; GO:0030308; GO:0030325; GO:0030509; GO:0030511; GO:0030513; GO:0031005; GO:0032444; GO:0032525; GO:0032909; GO:0032924; GO:0033686; GO:0035556; GO:0036302; GO:0042060; GO:0042118; GO:0042177; GO:0042733; GO:0042802; GO:0042803; GO:0043199; GO:0045892; GO:0045893; GO:0045944; GO:0046872; GO:0046881; GO:0048589; GO:0048663; GO:0048733; GO:0048859; GO:0051098; GO:0051571; GO:0051797; GO:0060065; GO:0060391; GO:0060395; GO:0060412; GO:0060548; GO:0060956; GO:0061040; GO:0061629; GO:0062009; GO:0070102; GO:0070371; GO:0070373; GO:0070411; GO:0070412; GO:0071141; GO:0071144; GO:0071333; GO:0071559; GO:0071773; GO:0072133; GO:0072134; GO:0072520; GO:1901522; GO:1902895; GO:1905305; GO:2000617 22759 XM_029323738.2 440 215 238 559 396 Q13485 4.58e-41 Mothers against decapentaplegic homolog 4 (MAD homolog 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4) (SMAD family member 4) (SMAD 4) (Smad4) (hSMAD4) Homo sapiens (Human) activin receptor signaling pathway [GO:0032924]; adrenal gland development [GO:0030325]; aging [GO:0007568]; anatomical structure morphogenesis [GO:0009653]; atrioventricular canal development [GO:0036302]; atrioventricular valve formation [GO:0003190]; axon guidance [GO:0007411]; BMP signaling pathway [GO:0030509]; brainstem development [GO:0003360]; branching involved in ureteric bud morphogenesis [GO:0001658]; cardiac conduction system development [GO:0003161]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular iron ion homeostasis [GO:0006879]; cellular response to BMP stimulus [GO:0071773]; cellular response to glucose stimulus [GO:0071333]; developmental growth [GO:0048589]; DNA-templated transcription [GO:0006351]; embryonic digit morphogenesis [GO:0042733]; endocardial cell differentiation [GO:0060956]; endoderm development [GO:0007492]; endothelial cell activation [GO:0042118]; epithelial cell migration [GO:0010631]; epithelial to mesenchymal transition [GO:0001837]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; ERK1 and ERK2 cascade [GO:0070371]; female gonad morphogenesis [GO:0061040]; formation of anatomical boundary [GO:0048859]; gastrulation with mouth forming second [GO:0001702]; in utero embryonic development [GO:0001701]; interleukin-6-mediated signaling pathway [GO:0070102]; intracellular signal transduction [GO:0035556]; left ventricular cardiac muscle tissue morphogenesis [GO:0003220]; mesoderm development [GO:0007498]; metanephric mesenchyme morphogenesis [GO:0072133]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of cardiac myofibril assembly [GO:1905305]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nephrogenic mesenchyme morphogenesis [GO:0072134]; neural crest cell differentiation [GO:0014033]; neuron fate commitment [GO:0048663]; osteoblast differentiation [GO:0001649]; outflow tract septum morphogenesis [GO:0003148]; ovarian follicle development [GO:0001541]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell proliferation involved in heart valve morphogenesis [GO:0003251]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of follicle-stimulating hormone secretion [GO:0046881]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of histone H3-K9 acetylation [GO:2000617]; positive regulation of luteinizing hormone secretion [GO:0033686]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; regulation of binding [GO:0051098]; regulation of hair follicle development [GO:0051797]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; regulation of transforming growth factor beta2 production [GO:0032909]; response to hypoxia [GO:0001666]; response to transforming growth factor beta [GO:0071559]; sebaceous gland development [GO:0048733]; secondary palate development [GO:0062009]; seminiferous tubule development [GO:0072520]; single fertilization [GO:0007338]; SMAD protein complex assembly [GO:0007183]; SMAD protein signal transduction [GO:0060395]; somite rostral/caudal axis specification [GO:0032525]; spermatogenesis [GO:0007283]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]; uterus development [GO:0060065]; ventricular septum morphogenesis [GO:0060412]; wound healing [GO:0042060] GO:0000122; GO:0000785; GO:0000976; GO:0000978; GO:0000981; GO:0001223; GO:0001228; GO:0001541; GO:0001649; GO:0001658; GO:0001666; GO:0001701; GO:0001702; GO:0001837; GO:0003148; GO:0003161; GO:0003190; GO:0003198; GO:0003220; GO:0003251; GO:0003360; GO:0003682; GO:0005518; GO:0005634; GO:0005654; GO:0005667; GO:0005737; GO:0005813; GO:0005829; GO:0006351; GO:0006366; GO:0006879; GO:0007179; GO:0007183; GO:0007283; GO:0007338; GO:0007411; GO:0007492; GO:0007498; GO:0007568; GO:0008283; GO:0008285; GO:0009653; GO:0010614; GO:0010631; GO:0010666; GO:0010718; GO:0010862; GO:0014033; GO:0017015; GO:0030154; GO:0030308; GO:0030325; GO:0030509; GO:0030511; GO:0030513; GO:0031005; GO:0032444; GO:0032525; GO:0032909; GO:0032924; GO:0033686; GO:0035556; GO:0036302; GO:0042060; GO:0042118; GO:0042177; GO:0042733; GO:0042802; GO:0042803; GO:0043199; GO:0045892; GO:0045893; GO:0045944; GO:0046872; GO:0046881; GO:0048589; GO:0048663; GO:0048733; GO:0048859; GO:0051098; GO:0051571; GO:0051797; GO:0060065; GO:0060391; GO:0060395; GO:0060412; GO:0060548; GO:0060956; GO:0061040; GO:0061629; GO:0062009; GO:0070102; GO:0070371; GO:0070373; GO:0070411; GO:0070412; GO:0071141; GO:0071144; GO:0071333; GO:0071559; GO:0071773; GO:0072133; GO:0072134; GO:0072520; GO:1901522; GO:1902895; GO:1905305; GO:2000617 22760 XM_044323962.1 0 0 10 0 0 NA NA NA NA NA NA 22761 XM_029343065.2 0 0 4 0 18 P54833 6.93e-25 Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor) Canis lupus familiaris (Dog) (Canis familiaris) activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; desensitization of G protein-coupled receptor signaling pathway by arrestin [GO:0002032]; negative regulation of smooth muscle contraction [GO:0045986]; norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0002025]; positive regulation of autophagosome maturation [GO:1901098]; positive regulation of lipophagy [GO:1904504]; positive regulation of MAPK cascade [GO:0043410]; receptor-mediated endocytosis [GO:0006898] GO:0002025; GO:0002032; GO:0004930; GO:0004941; GO:0005769; GO:0005794; GO:0005886; GO:0006898; GO:0007190; GO:0042803; GO:0043235; GO:0043410; GO:0045986; GO:0051380; GO:0071880; GO:1901098; GO:1904504 22762 XM_044309855.1 119 79 490 75 535 NA NA NA NA NA NA 22763 XM_044320189.1 43 20 12 55 64 NA NA NA NA NA NA 22764 XM_044320813.1 14 1 31 0 41 Q09575 4.64e-45 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 22765 XM_029328893.2 615 40 406 246 615 Q5GN48 5.38e-106 Dystrophin Sus scrofa (Pig) synaptic signaling [GO:0099536] GO:0003779; GO:0005737; GO:0005856; GO:0005886; GO:0008270; GO:0042383; GO:0045211; GO:0099536; GO:0120025 22766 XM_044309276.1 12 0 0 17 0 NA NA NA NA NA NA 22767 XM_029348909.2 490 635 211 405 1257 NA NA NA NA NA NA 22768 XR_003828198.2 9 0 0 3 2 NA NA NA NA NA NA 22769 XM_044312785.1 429 218 38 81 170 NA NA NA NA NA NA 22770 XM_044313722.1 3 113 32 175 69 A1L314 1.34e-155 Macrophage-expressed gene 1 protein (Macrophage gene 1 protein) (Mpg-1) (Perforin-2) (P-2) (Protein MPS1) Mus musculus (Mouse) antibacterial innate immune response [GO:0140367]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; disruption by host of symbiont membrane [GO:0052337] GO:0030659; GO:0031410; GO:0042742; GO:0045335; GO:0050829; GO:0050830; GO:0052337; GO:0140367 22771 XM_044313199.1 8 0 17 5 71 NA NA NA NA NA NA 22772 XM_029336370.2 939 747 658 589 836 Q6ZMV9 1.08e-70 Kinesin-like protein KIF6 Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0003777; GO:0005524; GO:0005737; GO:0005871; GO:0005874; GO:0007018; GO:0008017; GO:0016887 22773 XM_029350885.2 1459 1242 937 1230 889 Q5ZLC6 3.25e-36 Ankyrin repeat domain-containing protein 10 Gallus gallus (Chicken) NA NA 22774 XM_044317548.1 41 1 9 41 33 NA NA NA NA NA NA 22775 XM_044326656.1 1591 1820 880 1311 1013 Q58DA6 1.66e-111 UDP-galactose translocator (Solute carrier family 35 member A2) (UDP-galactose transporter) (UDP-Gal-Tr) (UGT) Bos taurus (Bovine) carbohydrate transport [GO:0008643] GO:0000139; GO:0008643; GO:0015165 22776 XM_044328236.1 193 78 77 122 63 Q6PC60 3.93e-59 Histone H2B 3 Danio rerio (Zebrafish) (Brachydanio rerio) nucleosome assembly [GO:0006334] GO:0000785; GO:0000786; GO:0003677; GO:0005634; GO:0006334; GO:0030527; GO:0046982 22777 XM_044321116.1 29 22 2 100 65 Q9H1A4 0 Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Mitotic checkpoint regulator) (Testis-specific gene 24 protein) Homo sapiens (Human) anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; metaphase/anaphase transition of mitotic cell cycle [GO:0007091]; protein K11-linked ubiquitination [GO:0070979]; regulation of meiotic cell cycle [GO:0051445]; regulation of mitotic cell cycle [GO:0007346] GO:0005654; GO:0005680; GO:0005829; GO:0007091; GO:0007346; GO:0031145; GO:0051301; GO:0051445; GO:0060090; GO:0070979 22778 XM_044328413.1 8 12 13 83 48 Q4R4J0 3.03e-63 Rho GDP-dissociation inhibitor 1 (Rho GDI 1) (Rho-GDI alpha) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526] GO:0005094; GO:0005096; GO:0005737; GO:0007266; GO:0071526 22779 XM_044312705.1 2 0 3 0 6 NA NA NA NA NA NA 22780 XM_029351260.2 89 43 54 40 101 G8XYX6 2.04e-33 Monocarboxylate transporter 8 (MCT 8) (Solute carrier family 16 member 2) Danio rerio (Zebrafish) (Brachydanio rerio) brain development [GO:0007420]; central nervous system development [GO:0007417]; chordate embryonic development [GO:0043009]; locomotion [GO:0040011]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; Schwann cell differentiation [GO:0014037]; spinal cord development [GO:0021510]; spinal cord oligodendrocyte cell differentiation [GO:0021529]; thyroid gland development [GO:0030878] GO:0007417; GO:0007420; GO:0014037; GO:0015349; GO:0016324; GO:0021510; GO:0021529; GO:0030182; GO:0030878; GO:0040011; GO:0043009; GO:0048709; GO:0070324 22781 XM_044307555.1 127 221 11 38 115 NA NA NA NA NA NA 22782 XR_006397067.1 40 14 0 13 11 NA NA NA NA NA NA 22783 XM_029356341.2 3390 2358 1566 2882 2412 NA NA NA NA NA NA 22784 XM_029339502.2 0 0 0 53 10 NA NA NA NA NA NA 22785 XM_044312891.1 26 0 39 0 108 Q7TN88 6.67e-73 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 22786 XR_003824969.2 34 89 17 36 40 NA NA NA NA NA NA 22787 XM_044318575.1 71 0 73 0 61 Q68F72 6.65e-92 Solute carrier family 15 member 4 Xenopus laevis (African clawed frog) dipeptide import across plasma membrane [GO:0140206]; innate immune response [GO:0045087]; mast cell homeostasis [GO:0033023]; peptidoglycan transport [GO:0015835]; positive regulation of innate immune response [GO:0045089]; positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [GO:0070430]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of toll-like receptor 7 signaling pathway [GO:0034157]; positive regulation of toll-like receptor 8 signaling pathway [GO:0034161]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; protein transport [GO:0015031]; regulation of isotype switching to IgG isotypes [GO:0048302]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424] GO:0005290; GO:0005765; GO:0015031; GO:0015333; GO:0015647; GO:0015835; GO:0031901; GO:0033023; GO:0034157; GO:0034161; GO:0034165; GO:0036020; GO:0045087; GO:0045089; GO:0048302; GO:0070424; GO:0070430; GO:0070434; GO:0071916; GO:0140206 22788 XM_029333257.2 3362 5758 3231 5118 3016 NA NA NA NA NA NA 22789 XM_044318623.1 1125 586 672 1645 944 P22811 0 Xanthine dehydrogenase (XD) (EC 1.17.1.4) (Protein rosy locus) Drosophila pseudoobscura pseudoobscura (Fruit fly) arginine metabolic process [GO:0006525]; determination of adult lifespan [GO:0008340]; glycerophospholipid metabolic process [GO:0006650]; pyrimidine nucleobase metabolic process [GO:0006206]; tryptophan metabolic process [GO:0006568]; xanthine catabolic process [GO:0009115] GO:0004854; GO:0005506; GO:0005777; GO:0006206; GO:0006525; GO:0006568; GO:0006650; GO:0008340; GO:0009115; GO:0043546; GO:0050660; GO:0051537; GO:0071949 22790 XM_029350122.2 133 166 131 242 177 NA NA NA NA NA NA 22791 XM_044314174.1 57 42 36 3 35 Q91287 1.8e-76 Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (PFR3) Pleurodeles waltl (Iberian ribbed newt) apoptotic process [GO:0006915]; positive regulation of cell population proliferation [GO:0008284] GO:0005007; GO:0005524; GO:0005886; GO:0006915; GO:0008284 22792 XM_044314174.1 57 42 36 3 35 Q91287 6.94e-38 Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (PFR3) Pleurodeles waltl (Iberian ribbed newt) apoptotic process [GO:0006915]; positive regulation of cell population proliferation [GO:0008284] GO:0005007; GO:0005524; GO:0005886; GO:0006915; GO:0008284 22793 XM_029339332.2 586 477 428 630 475 P22062 1.07e-94 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PIMT) (EC 2.1.1.77) (L-isoaspartyl protein carboxyl methyltransferase) (Protein L-isoaspartyl/D-aspartyl methyltransferase) (Protein-beta-aspartate methyltransferase) Rattus norvegicus (Rat) aging [GO:0007568]; cellular response to hypoxia [GO:0071456]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; protein methylation [GO:0006479]; response to ethanol [GO:0045471]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500] GO:0004719; GO:0005615; GO:0005737; GO:0005829; GO:0006479; GO:0007568; GO:0008757; GO:0010667; GO:0016323; GO:0031526; GO:0043005; GO:0043204; GO:0045471; GO:0046498; GO:0046500; GO:0071456 22794 XM_029357473.2 2344 2314 1888 2196 2247 Q8T3X9 6.25e-59 Iron-sulfur cluster assembly 1 homolog, mitochondrial (Lethal (1) G0136) (Putative magnetoreceptor subunit MagR) Drosophila melanogaster (Fruit fly) iron-sulfur cluster assembly [GO:0016226]; protein maturation by iron-sulfur cluster transfer [GO:0097428]; response to magnetism [GO:0071000] GO:0005737; GO:0005739; GO:0016226; GO:0046872; GO:0051537; GO:0071000; GO:0097428 22795 XM_044328328.1 0 204 0 0 0 Q5VV67 2.68e-22 Peroxisome proliferator-activated receptor gamma coactivator-related protein 1 (PGC-1-related coactivator) (PRC) Homo sapiens (Human) positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0003723; GO:0005634; GO:0005654; GO:0030374; GO:0045944; GO:0051091 22796 XM_044322654.1 107 1 49 53 49 NA NA NA NA NA NA 22797 XM_029347945.2 246 254 122 236 213 NA NA NA NA NA NA 22798 XM_044313303.1 511 419 210 566 752 Q8R1A4 0 Dedicator of cytokinesis protein 7 (Protein moonlight) Mus musculus (Mouse) activation of GTPase activity [GO:0090630]; axonogenesis [GO:0007409]; establishment of neuroblast polarity [GO:0045200]; hematopoietic progenitor cell differentiation [GO:0002244]; interkinetic nuclear migration [GO:0022027]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of cold-induced thermogenesis [GO:0120163]; neuron projection development [GO:0031175]; pigmentation [GO:0043473]; positive regulation of GTPase activity [GO:0043547]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; postsynaptic specialization assembly [GO:0098698]; regulation of neurogenesis [GO:0050767]; small GTPase mediated signal transduction [GO:0007264] GO:0000226; GO:0002244; GO:0005085; GO:0007264; GO:0007409; GO:0008180; GO:0022027; GO:0030424; GO:0031175; GO:0031267; GO:0031594; GO:0033138; GO:0043473; GO:0043547; GO:0045200; GO:0050767; GO:0090630; GO:0098698; GO:0120163; GO:1904754 22799 XM_029349017.2 23 9 14 25 42 NA NA NA NA NA NA 22800 XM_044314865.1 109 55 57 79 80 C3ZQF9 5.72e-25 QRFP-like peptide receptor Branchiostoma floridae (Florida lancelet) (Amphioxus) cellular response to peptide [GO:1901653]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:1901653 22801 XM_044324796.1 13 0 8 27 0 NA NA NA NA NA NA 22802 XR_006395541.1 9 0 0 4 5 NA NA NA NA NA NA 22803 XM_029328864.2 701 406 97 611 54 Q8NI36 0 WD repeat-containing protein 36 (T-cell activation WD repeat-containing protein) (TA-WDRP) Homo sapiens (Human) response to stimulus [GO:0050896]; rRNA processing [GO:0006364]; visual perception [GO:0007601] GO:0003723; GO:0005654; GO:0005730; GO:0006364; GO:0007601; GO:0032040; GO:0034388; GO:0050896 22804 XM_044329273.1 14609 5199 6349 21908 20274 Q09666 3.63e-111 Neuroblast differentiation-associated protein AHNAK (Desmoyokin) Homo sapiens (Human) positive regulation of plasma membrane repair [GO:1905686]; regulation of RNA splicing [GO:0043484]; regulation of voltage-gated calcium channel activity [GO:1901385] GO:0003723; GO:0005634; GO:0005737; GO:0005765; GO:0005829; GO:0005886; GO:0005925; GO:0015629; GO:0016020; GO:0030315; GO:0031982; GO:0042383; GO:0042802; GO:0043034; GO:0043484; GO:0044291; GO:0044548; GO:0045296; GO:0070062; GO:0097493; GO:0098797; GO:1901385; GO:1905686 22805 XM_044329273.1 14609 5199 6349 21908 20274 Q09666 1.43e-109 Neuroblast differentiation-associated protein AHNAK (Desmoyokin) Homo sapiens (Human) positive regulation of plasma membrane repair [GO:1905686]; regulation of RNA splicing [GO:0043484]; regulation of voltage-gated calcium channel activity [GO:1901385] GO:0003723; GO:0005634; GO:0005737; GO:0005765; GO:0005829; GO:0005886; GO:0005925; GO:0015629; GO:0016020; GO:0030315; GO:0031982; GO:0042383; GO:0042802; GO:0043034; GO:0043484; GO:0044291; GO:0044548; GO:0045296; GO:0070062; GO:0097493; GO:0098797; GO:1901385; GO:1905686 22806 XM_044329273.1 14609 5199 6349 21908 20274 Q09666 1.95e-109 Neuroblast differentiation-associated protein AHNAK (Desmoyokin) Homo sapiens (Human) positive regulation of plasma membrane repair [GO:1905686]; regulation of RNA splicing [GO:0043484]; regulation of voltage-gated calcium channel activity [GO:1901385] GO:0003723; GO:0005634; GO:0005737; GO:0005765; GO:0005829; GO:0005886; GO:0005925; GO:0015629; GO:0016020; GO:0030315; GO:0031982; GO:0042383; GO:0042802; GO:0043034; GO:0043484; GO:0044291; GO:0044548; GO:0045296; GO:0070062; GO:0097493; GO:0098797; GO:1901385; GO:1905686 22807 XM_044329273.1 14609 5199 6349 21908 20274 Q09666 3.49e-107 Neuroblast differentiation-associated protein AHNAK (Desmoyokin) Homo sapiens (Human) positive regulation of plasma membrane repair [GO:1905686]; regulation of RNA splicing [GO:0043484]; regulation of voltage-gated calcium channel activity [GO:1901385] GO:0003723; GO:0005634; GO:0005737; GO:0005765; GO:0005829; GO:0005886; GO:0005925; GO:0015629; GO:0016020; GO:0030315; GO:0031982; GO:0042383; GO:0042802; GO:0043034; GO:0043484; GO:0044291; GO:0044548; GO:0045296; GO:0070062; GO:0097493; GO:0098797; GO:1901385; GO:1905686 22808 XM_044329273.1 14609 5199 6349 21908 20274 Q09666 1.45e-104 Neuroblast differentiation-associated protein AHNAK (Desmoyokin) Homo sapiens (Human) positive regulation of plasma membrane repair [GO:1905686]; regulation of RNA splicing [GO:0043484]; regulation of voltage-gated calcium channel activity [GO:1901385] GO:0003723; GO:0005634; GO:0005737; GO:0005765; GO:0005829; GO:0005886; GO:0005925; GO:0015629; GO:0016020; GO:0030315; GO:0031982; GO:0042383; GO:0042802; GO:0043034; GO:0043484; GO:0044291; GO:0044548; GO:0045296; GO:0070062; GO:0097493; GO:0098797; GO:1901385; GO:1905686 22809 XM_044329273.1 14609 5199 6349 21908 20274 Q09666 1.19e-102 Neuroblast differentiation-associated protein AHNAK (Desmoyokin) Homo sapiens (Human) positive regulation of plasma membrane repair [GO:1905686]; regulation of RNA splicing [GO:0043484]; regulation of voltage-gated calcium channel activity [GO:1901385] GO:0003723; GO:0005634; GO:0005737; GO:0005765; GO:0005829; GO:0005886; GO:0005925; GO:0015629; GO:0016020; GO:0030315; GO:0031982; GO:0042383; GO:0042802; GO:0043034; GO:0043484; GO:0044291; GO:0044548; GO:0045296; GO:0070062; GO:0097493; GO:0098797; GO:1901385; GO:1905686 22810 XM_044329273.1 14609 5199 6349 21908 20274 Q09666 3.01e-97 Neuroblast differentiation-associated protein AHNAK (Desmoyokin) Homo sapiens (Human) positive regulation of plasma membrane repair [GO:1905686]; regulation of RNA splicing [GO:0043484]; regulation of voltage-gated calcium channel activity [GO:1901385] GO:0003723; GO:0005634; GO:0005737; GO:0005765; GO:0005829; GO:0005886; GO:0005925; GO:0015629; GO:0016020; GO:0030315; GO:0031982; GO:0042383; GO:0042802; GO:0043034; GO:0043484; GO:0044291; GO:0044548; GO:0045296; GO:0070062; GO:0097493; GO:0098797; GO:1901385; GO:1905686 22811 XM_044329273.1 14609 5199 6349 21908 20274 Q09666 1.91e-83 Neuroblast differentiation-associated protein AHNAK (Desmoyokin) Homo sapiens (Human) positive regulation of plasma membrane repair [GO:1905686]; regulation of RNA splicing [GO:0043484]; regulation of voltage-gated calcium channel activity [GO:1901385] GO:0003723; GO:0005634; GO:0005737; GO:0005765; GO:0005829; GO:0005886; GO:0005925; GO:0015629; GO:0016020; GO:0030315; GO:0031982; GO:0042383; GO:0042802; GO:0043034; GO:0043484; GO:0044291; GO:0044548; GO:0045296; GO:0070062; GO:0097493; GO:0098797; GO:1901385; GO:1905686 22812 XM_044329273.1 14609 5199 6349 21908 20274 Q09666 1.64e-79 Neuroblast differentiation-associated protein AHNAK (Desmoyokin) Homo sapiens (Human) positive regulation of plasma membrane repair [GO:1905686]; regulation of RNA splicing [GO:0043484]; regulation of voltage-gated calcium channel activity [GO:1901385] GO:0003723; GO:0005634; GO:0005737; GO:0005765; GO:0005829; GO:0005886; GO:0005925; GO:0015629; GO:0016020; GO:0030315; GO:0031982; GO:0042383; GO:0042802; GO:0043034; GO:0043484; GO:0044291; GO:0044548; GO:0045296; GO:0070062; GO:0097493; GO:0098797; GO:1901385; GO:1905686 22813 XM_044329273.1 14609 5199 6349 21908 20274 Q09666 4.05e-66 Neuroblast differentiation-associated protein AHNAK (Desmoyokin) Homo sapiens (Human) positive regulation of plasma membrane repair [GO:1905686]; regulation of RNA splicing [GO:0043484]; regulation of voltage-gated calcium channel activity [GO:1901385] GO:0003723; GO:0005634; GO:0005737; GO:0005765; GO:0005829; GO:0005886; GO:0005925; GO:0015629; GO:0016020; GO:0030315; GO:0031982; GO:0042383; GO:0042802; GO:0043034; GO:0043484; GO:0044291; GO:0044548; GO:0045296; GO:0070062; GO:0097493; GO:0098797; GO:1901385; GO:1905686 22814 XM_044329273.1 14609 5199 6349 21908 20274 Q09666 2.88e-51 Neuroblast differentiation-associated protein AHNAK (Desmoyokin) Homo sapiens (Human) positive regulation of plasma membrane repair [GO:1905686]; regulation of RNA splicing [GO:0043484]; regulation of voltage-gated calcium channel activity [GO:1901385] GO:0003723; GO:0005634; GO:0005737; GO:0005765; GO:0005829; GO:0005886; GO:0005925; GO:0015629; GO:0016020; GO:0030315; GO:0031982; GO:0042383; GO:0042802; GO:0043034; GO:0043484; GO:0044291; GO:0044548; GO:0045296; GO:0070062; GO:0097493; GO:0098797; GO:1901385; GO:1905686 22815 XM_044313508.1 97 81 46 135 90 NA NA NA NA NA NA 22816 XM_044307134.1 111 87 211 0 555 NA NA NA NA NA NA 22817 XR_003825280.2 200 112 99 164 205 NA NA NA NA NA NA 22818 XM_029329203.2 244 125 117 132 198 Q4V9P6 7.02e-118 Adenosine deaminase-like protein (EC 3.5.4.-) Danio rerio (Zebrafish) (Brachydanio rerio) adenosine catabolic process [GO:0006154]; inosine biosynthetic process [GO:0046103]; nucleotide metabolic process [GO:0009117] GO:0004000; GO:0006154; GO:0009117; GO:0046103; GO:0046872; GO:0062154 22819 XR_006397206.1 19 7 19 22 137 NA NA NA NA NA NA 22820 XM_029332287.2 17 8 10 11 12 P00185 4.95e-35 Cytochrome P450 1A1 (CYP1A1) (EC 1.14.14.1) (CYPIA1) (Cytochrome P450 form 6) (Cytochrome P450-C) (Cytochrome P450-P1) (Cytochrome P450MT2) (Hydroperoxy icosatetraenoate dehydratase) (EC 4.2.1.152) [Cleaved into: Cytochrome P450MT2A; Cytochrome P450MT2B] Rattus norvegicus (Rat) 9-cis-retinoic acid biosynthetic process [GO:0042904]; aging [GO:0007568]; amine metabolic process [GO:0009308]; camera-type eye development [GO:0043010]; cell population proliferation [GO:0008283]; cellular response to copper ion [GO:0071280]; cellular response to organic cyclic compound [GO:0071407]; coumarin metabolic process [GO:0009804]; developmental process [GO:0032502]; dibenzo-p-dioxin catabolic process [GO:0019341]; dibenzo-p-dioxin metabolic process [GO:0018894]; digestive tract development [GO:0048565]; DNA methylation [GO:0006306]; estrogen metabolic process [GO:0008210]; fatty acid metabolic process [GO:0006631]; flavonoid metabolic process [GO:0009812]; hepatocyte differentiation [GO:0070365]; heterocycle metabolic process [GO:0046483]; hydrogen peroxide biosynthetic process [GO:0050665]; insecticide metabolic process [GO:0017143]; lipid hydroxylation [GO:0002933]; liver development [GO:0001889]; long-chain fatty acid metabolic process [GO:0001676]; maternal process involved in parturition [GO:0060137]; porphyrin-containing compound metabolic process [GO:0006778]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; response to antibiotic [GO:0046677]; response to arsenic-containing substance [GO:0046685]; response to food [GO:0032094]; response to herbicide [GO:0009635]; response to hyperoxia [GO:0055093]; response to hypoxia [GO:0001666]; response to immobilization stress [GO:0035902]; response to iron(III) ion [GO:0010041]; response to lipopolysaccharide [GO:0032496]; response to nematode [GO:0009624]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to toxic substance [GO:0009636]; response to virus [GO:0009615]; response to vitamin A [GO:0033189]; response to wounding [GO:0009611]; response to xenobiotic stimulus [GO:0009410]; retinol metabolic process [GO:0042572]; steroid biosynthetic process [GO:0006694]; steroid metabolic process [GO:0008202]; toxin metabolic process [GO:0009404]; xenobiotic metabolic process [GO:0006805] GO:0001666; GO:0001676; GO:0001889; GO:0002933; GO:0003824; GO:0004497; GO:0005506; GO:0005737; GO:0005739; GO:0005743; GO:0005789; GO:0006306; GO:0006631; GO:0006694; GO:0006778; GO:0006805; GO:0007568; GO:0008202; GO:0008210; GO:0008283; GO:0008391; GO:0008395; GO:0009308; GO:0009404; GO:0009410; GO:0009611; GO:0009615; GO:0009624; GO:0009635; GO:0009636; GO:0009804; GO:0009812; GO:0010033; GO:0010041; GO:0014070; GO:0016491; GO:0016679; GO:0016711; GO:0016712; GO:0017143; GO:0018894; GO:0019341; GO:0019899; GO:0020037; GO:0030544; GO:0032094; GO:0032451; GO:0032496; GO:0032502; GO:0033189; GO:0035902; GO:0042572; GO:0042904; GO:0043010; GO:0043231; GO:0046483; GO:0046677; GO:0046685; GO:0048565; GO:0050665; GO:0051879; GO:0055093; GO:0060137; GO:0070330; GO:0070365; GO:0070576; GO:0071280; GO:0071407; GO:0101020; GO:0101021; GO:0102033; GO:0106256; GO:0120319; GO:1900087 22821 XM_029346805.2 35 12 43 2 210 NA NA NA NA NA NA 22822 XM_029336688.2 915 537 445 716 563 Q9WTV0 9.03e-48 Prolactin regulatory element-binding protein (Mammalian guanine nucleotide exchange factor mSec12) Rattus norvegicus (Rat) COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein exit from endoplasmic reticulum [GO:0032527]; protein secretion [GO:0009306]; regulation of COPII vesicle coating [GO:0003400] GO:0000978; GO:0003400; GO:0005085; GO:0005096; GO:0005634; GO:0005789; GO:0006888; GO:0009306; GO:0032527; GO:0045944; GO:0048208; GO:0051020; GO:0070971 22823 XM_029328550.2 0 0 0 87 0 NA NA NA NA NA NA 22824 XM_044328101.1 0 0 0 249 0 NA NA NA NA NA NA 22825 XM_029337506.2 3232 2902 2238 5738 3388 F1R8Z9 3.4e-52 Forkhead box protein J1-B Danio rerio (Zebrafish) (Brachydanio rerio) auditory receptor cell stereocilium organization [GO:0060088]; cilium assembly [GO:0060271]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; heart looping [GO:0001947]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0001947; GO:0003146; GO:0005634; GO:0006357; GO:0007368; GO:0060088; GO:0060271 22826 XM_044311095.1 0 0 14 0 8 NA NA NA NA NA NA 22827 XM_029348033.2 2121 1689 956 1406 1072 Q9NQZ5 5.26e-71 StAR-related lipid transfer protein 7, mitochondrial (Gestational trophoblastic tumor protein 1) (START domain-containing protein 7) (StARD7) Homo sapiens (Human) NA GO:0005741; GO:0008289 22828 XM_044311397.1 40 145 104 203 415 O09173 8.7e-67 Homogentisate 1,2-dioxygenase (EC 1.13.11.5) (Homogentisate oxygenase) (Homogentisic acid oxidase) (Homogentisicase) Mus musculus (Mouse) amino acid metabolic process [GO:0006520]; L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572] GO:0004411; GO:0006520; GO:0006559; GO:0006572; GO:0042802; GO:0046872 22829 XM_044324754.1 6 32 2 145 0 NA NA NA NA NA NA 22830 XM_029344068.2 860 761 445 610 428 Q9EP80 4.78e-180 PRKCA-binding protein (Protein interacting with C kinase 1) (Protein kinase C-alpha-binding protein) Rattus norvegicus (Rat) cellular response to decreased oxygen levels [GO:0036294]; cellular response to glucose starvation [GO:0042149]; dendritic spine maintenance [GO:0097062]; dendritic spine organization [GO:0097061]; dopamine transport [GO:0015872]; glial cell development [GO:0021782]; intracellular protein transport [GO:0006886]; long-term synaptic depression [GO:0060292]; monoamine transport [GO:0015844]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; negative regulation of cell death [GO:0060548]; negative regulation of gene expression [GO:0010629]; positive regulation of receptor internalization [GO:0002092]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; protein phosphorylation [GO:0006468]; protein targeting [GO:0006605]; receptor clustering [GO:0043113]; regulation of Arp2/3 complex-mediated actin nucleation [GO:0034315]; regulation of insulin secretion [GO:0050796]; regulation of kainate selective glutamate receptor activity [GO:2000312]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149] GO:0001664; GO:0002092; GO:0005080; GO:0005102; GO:0005484; GO:0005543; GO:0005737; GO:0005739; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006468; GO:0006605; GO:0006886; GO:0007205; GO:0008021; GO:0008022; GO:0008092; GO:0010629; GO:0014069; GO:0015844; GO:0015872; GO:0016020; GO:0019899; GO:0019904; GO:0021782; GO:0030425; GO:0030971; GO:0032588; GO:0032991; GO:0034315; GO:0034316; GO:0035255; GO:0035256; GO:0036294; GO:0042149; GO:0042734; GO:0042802; GO:0043005; GO:0043113; GO:0043197; GO:0045202; GO:0046872; GO:0046875; GO:0048471; GO:0050796; GO:0051015; GO:0051020; GO:0060292; GO:0060548; GO:0071933; GO:0097061; GO:0097062; GO:0098842; GO:0098843; GO:0098978; GO:0099149; GO:0099572; GO:0140090; GO:2000312 22831 XM_044316435.1 0 0 0 11 0 NA NA NA NA NA NA 22832 XM_044315172.1 0 138 0 0 127 P97321 4.96e-45 Prolyl endopeptidase FAP (EC 3.4.21.26) (Dipeptidyl peptidase FAP) (EC 3.4.14.5) (Fibroblast activation protein alpha) (FAPalpha) (Gelatine degradation protease FAP) (EC 3.4.21.-) (Integral membrane serine protease) (Post-proline cleaving enzyme) (Serine integral membrane protease) (SIMP) (Surface-expressed protease) (Seprase) [Cleaved into: Antiplasmin-cleaving enzyme FAP, soluble form (APCE) (EC 3.4.14.5) (EC 3.4.21.-) (EC 3.4.21.26)] Mus musculus (Mouse) angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; melanocyte apoptotic process [GO:1902362]; melanocyte proliferation [GO:0097325]; negative regulation of cell proliferation involved in contact inhibition [GO:0060244]; negative regulation of extracellular matrix disassembly [GO:0010716]; negative regulation of extracellular matrix organization [GO:1903054]; positive regulation of execution phase of apoptosis [GO:1900119]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of cell cycle [GO:0051726]; regulation of collagen catabolic process [GO:0010710] GO:0001525; GO:0002020; GO:0004175; GO:0004252; GO:0005178; GO:0005615; GO:0005886; GO:0006508; GO:0007155; GO:0008233; GO:0008236; GO:0008239; GO:0009986; GO:0010710; GO:0010716; GO:0030027; GO:0031258; GO:0032587; GO:0042802; GO:0042803; GO:0043542; GO:0045177; GO:0045178; GO:0051603; GO:0051726; GO:0060244; GO:0070161; GO:0097325; GO:1900119; GO:1902362; GO:1903054; GO:1905368 22833 XM_044315172.1 0 138 0 0 127 P97321 4.96e-45 Prolyl endopeptidase FAP (EC 3.4.21.26) (Dipeptidyl peptidase FAP) (EC 3.4.14.5) (Fibroblast activation protein alpha) (FAPalpha) (Gelatine degradation protease FAP) (EC 3.4.21.-) (Integral membrane serine protease) (Post-proline cleaving enzyme) (Serine integral membrane protease) (SIMP) (Surface-expressed protease) (Seprase) [Cleaved into: Antiplasmin-cleaving enzyme FAP, soluble form (APCE) (EC 3.4.14.5) (EC 3.4.21.-) (EC 3.4.21.26)] Mus musculus (Mouse) angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; melanocyte apoptotic process [GO:1902362]; melanocyte proliferation [GO:0097325]; negative regulation of cell proliferation involved in contact inhibition [GO:0060244]; negative regulation of extracellular matrix disassembly [GO:0010716]; negative regulation of extracellular matrix organization [GO:1903054]; positive regulation of execution phase of apoptosis [GO:1900119]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of cell cycle [GO:0051726]; regulation of collagen catabolic process [GO:0010710] GO:0001525; GO:0002020; GO:0004175; GO:0004252; GO:0005178; GO:0005615; GO:0005886; GO:0006508; GO:0007155; GO:0008233; GO:0008236; GO:0008239; GO:0009986; GO:0010710; GO:0010716; GO:0030027; GO:0031258; GO:0032587; GO:0042802; GO:0042803; GO:0043542; GO:0045177; GO:0045178; GO:0051603; GO:0051726; GO:0060244; GO:0070161; GO:0097325; GO:1900119; GO:1902362; GO:1903054; GO:1905368 22834 XM_044320933.1 86 123 56 129 169 NA NA NA NA NA NA 22835 XR_006393989.1 14 0 6 0 0 Q8BH74 0 Nuclear pore complex protein Nup107 (107 kDa nucleoporin) (Nucleoporin Nup107) Mus musculus (Mouse) female gonad development [GO:0008585]; mRNA export from nucleus [GO:0006406]; nephron development [GO:0072006]; nuclear pore complex assembly [GO:0051292]; nucleocytoplasmic transport [GO:0006913]; post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000973]; protein import into nucleus [GO:0006606] GO:0000776; GO:0000973; GO:0005635; GO:0005643; GO:0006406; GO:0006606; GO:0006913; GO:0008585; GO:0017056; GO:0031080; GO:0031965; GO:0034399; GO:0051292; GO:0072006 22836 XM_029355503.2 691 458 210 519 317 Q86TI4 7.1e-85 WD repeat-containing protein 86 Homo sapiens (Human) NA NA 22837 XM_029355503.2 691 458 210 519 317 Q86TI4 2.02e-22 WD repeat-containing protein 86 Homo sapiens (Human) NA NA 22838 XM_044328683.1 0 7 11 0 110 P16065 0 Speract receptor (EC 4.6.1.2) (Guanylate cyclase) Strongylocentrotus purpuratus (Purple sea urchin) cGMP biosynthetic process [GO:0006182]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]; receptor guanylyl cyclase signaling pathway [GO:0007168]; signal transduction [GO:0007165] GO:0001653; GO:0004383; GO:0004672; GO:0005524; GO:0005525; GO:0005886; GO:0006182; GO:0006468; GO:0007165; GO:0007168; GO:0035556 22839 XM_044314921.1 305 281 2 280 256 NA NA NA NA NA NA 22840 XM_029341888.2 0 3 18 0 1750 P35224 0 Catenin beta (Beta-catenin) Urechis caupo (Innkeeper worm) (Spoonworm) cell adhesion [GO:0007155] GO:0005737; GO:0005856; GO:0007155; GO:0045296 22841 XM_044323710.1 3 3 7 1 5 NA NA NA NA NA NA 22842 XM_044315108.1 0 3 4 4 6 NA NA NA NA NA NA 22843 XR_006392225.1 10 13 38 28 0 NA NA NA NA NA NA 22844 XM_044328055.1 278 598 252 1811 1041 NA NA NA NA NA NA 22845 XR_006396537.1 16 4 0 1 14 NA NA NA NA NA NA 22846 XM_044324881.1 218 2 0 10 26 Q8N3S3 8.03e-105 Protein PHTF2 Homo sapiens (Human) NA GO:0005783; GO:0016020 22847 XM_044313871.1 824 597 498 839 479 Q9DBE9 2.02e-144 pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3 (EC 2.1.1.-) (Protein ftsJ homolog 3) (Putative rRNA methyltransferase 3) Mus musculus (Mouse) enzyme-directed rRNA 2'-O-methylation [GO:0000453]; maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000466]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; RNA methylation [GO:0001510]; rRNA methylation [GO:0031167] GO:0000453; GO:0000463; GO:0000466; GO:0001510; GO:0005654; GO:0005694; GO:0005730; GO:0008173; GO:0008650; GO:0016435; GO:0030687; GO:0030688; GO:0031167; GO:0062105 22848 XM_044313871.1 824 597 498 839 479 Q9DBE9 1.39e-41 pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3 (EC 2.1.1.-) (Protein ftsJ homolog 3) (Putative rRNA methyltransferase 3) Mus musculus (Mouse) enzyme-directed rRNA 2'-O-methylation [GO:0000453]; maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000466]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; RNA methylation [GO:0001510]; rRNA methylation [GO:0031167] GO:0000453; GO:0000463; GO:0000466; GO:0001510; GO:0005654; GO:0005694; GO:0005730; GO:0008173; GO:0008650; GO:0016435; GO:0030687; GO:0030688; GO:0031167; GO:0062105 22849 XM_044327390.1 34 9 0 4 0 NA NA NA NA NA NA 22850 XM_044308963.1 0 32 0 0 6 NA NA NA NA NA NA 22851 XM_029330909.2 53 8 29 102 90 NA NA NA NA NA NA 22852 XM_044322678.1 23 0 0 0 0 NA NA NA NA NA NA 22853 XM_044308160.1 589 154 246 475 462 P18298 0 S-adenosylmethionine synthase isoform type-2 (AdoMet synthase 2) (EC 2.5.1.6) (Methionine adenosyltransferase 2) (MAT 2) (Methionine adenosyltransferase II) (MAT-II) Rattus norvegicus (Rat) cellular response to leukemia inhibitory factor [GO:1990830]; circadian rhythm [GO:0007623]; one-carbon metabolic process [GO:0006730]; protein heterooligomerization [GO:0051291]; protein hexamerization [GO:0034214]; response to cAMP [GO:0051591]; response to hormone [GO:0009725]; response to light stimulus [GO:0009416]; response to xenobiotic stimulus [GO:0009410]; S-adenosylmethionine biosynthetic process [GO:0006556] GO:0004478; GO:0005524; GO:0005829; GO:0006556; GO:0006730; GO:0007623; GO:0009410; GO:0009416; GO:0009725; GO:0016597; GO:0034214; GO:0036094; GO:0042802; GO:0046872; GO:0048269; GO:0051291; GO:0051591; GO:1990830 22854 XM_029343613.2 658 431 419 366 279 Q99MU3 3.05e-119 Double-stranded RNA-specific adenosine deaminase (DRADA) (EC 3.5.4.37) (RNA adenosine deaminase 1) Mus musculus (Mouse) adenosine to inosine editing [GO:0006382]; apoptotic process [GO:0006915]; base conversion or substitution editing [GO:0016553]; cellular response to virus [GO:0098586]; defense response to virus [GO:0051607]; definitive hemopoiesis [GO:0060216]; erythrocyte differentiation [GO:0030218]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell homeostasis [GO:0061484]; hepatocyte apoptotic process [GO:0097284]; innate immune response [GO:0045087]; miRNA processing [GO:0035196]; mRNA processing [GO:0006397]; negative regulation of hepatocyte apoptotic process [GO:1903944]; negative regulation of post-transcriptional gene silencing by RNA [GO:1900369]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; osteoblast differentiation [GO:0001649]; positive regulation of viral genome replication [GO:0045070]; pre-miRNA processing [GO:0031054]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; response to interferon-alpha [GO:0035455]; response to virus [GO:0009615]; RISC complex assembly [GO:0070922]; RNA processing [GO:0006396]; somatic diversification of immune receptors via somatic mutation [GO:0002566] GO:0001649; GO:0002244; GO:0002566; GO:0003692; GO:0003725; GO:0003726; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0006382; GO:0006396; GO:0006397; GO:0006606; GO:0006611; GO:0006915; GO:0008251; GO:0009615; GO:0016553; GO:0016607; GO:0030218; GO:0031054; GO:0035196; GO:0035455; GO:0044387; GO:0044530; GO:0045070; GO:0045087; GO:0046872; GO:0051607; GO:0060216; GO:0060339; GO:0061484; GO:0070922; GO:0097284; GO:0098586; GO:1900369; GO:1903944 22855 XM_044316059.1 9 0 30 30 119 NA NA NA NA NA NA 22856 XM_029357464.2 278 183 20 185 184 NA NA NA NA NA NA 22857 XM_044309116.1 910 224 749 1046 473 NA NA NA NA NA NA 22858 XR_006393591.1 64 9 43 68 63 NA NA NA NA NA NA 22859 XM_029344536.2 781 938 572 822 771 P43234 8.75e-70 Cathepsin O (EC 3.4.22.42) Homo sapiens (Human) proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603] GO:0004197; GO:0005615; GO:0005764; GO:0006508; GO:0051603 22860 XM_029344555.2 1930 1398 1406 1846 1936 NA NA NA NA NA NA 22861 XM_029339341.2 2393 1455 1896 2239 2427 Q9UK61 6.39e-40 Protein TASOR (CTCL tumor antigen se89-1) (Retinoblastoma-associated protein RAP140) (Transgene activation suppressor protein) Homo sapiens (Human) anterior/posterior axis specification, embryo [GO:0008595]; mesodermal to mesenchymal transition involved in gastrulation [GO:0060809]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; positive regulation of DNA methylation-dependent heterochromatin formation [GO:0090309]; protein localization to heterochromatin [GO:0097355] GO:0000792; GO:0003682; GO:0003723; GO:0005654; GO:0008595; GO:0045814; GO:0045869; GO:0060809; GO:0090309; GO:0097355 22862 XM_029331097.2 313 96 125 175 240 Q9D0K0 6.34e-68 TBC1 domain family member 7 Mus musculus (Mouse) activation of GTPase activity [GO:0090630]; negative regulation of cilium assembly [GO:1902018]; negative regulation of TOR signaling [GO:0032007]; positive regulation of GTPase activity [GO:0043547]; positive regulation of protein ubiquitination [GO:0031398]; response to growth factor [GO:0070848] GO:0005096; GO:0031267; GO:0031398; GO:0031410; GO:0032007; GO:0033596; GO:0036064; GO:0043547; GO:0070848; GO:0090630; GO:1902018 22863 XR_006397147.1 1573 1103 954 1409 1509 Q28623 3.17e-122 Sarcolemmal membrane-associated protein (Sarcolemmal-associated protein) Oryctolagus cuniculus (Rabbit) NA GO:0005615; GO:0005737; GO:0005815; GO:0042383 22864 XM_044308439.1 85 279 178 244 248 NA NA NA NA NA NA 22865 XM_029356596.2 29 1 19 4 55 NA NA NA NA NA NA 22866 XM_029336613.2 415 121 176 317 421 Q8C5L6 1.23e-67 Inositol polyphosphate 5-phosphatase K (EC 3.1.3.56) (Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase) (EC 3.1.3.86) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (EC 3.1.3.36) (Skeletal muscle and kidney-enriched inositol phosphatase) Mus musculus (Mouse) cellular response to cAMP [GO:0071320]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to hormone stimulus [GO:0032870]; cellular response to insulin stimulus [GO:0032869]; cellular response to tumor necrosis factor [GO:0071356]; dephosphorylation [GO:0016311]; G protein-coupled receptor signaling pathway [GO:0007186]; glucose homeostasis [GO:0042593]; in utero embryonic development [GO:0001701]; inositol phosphate dephosphorylation [GO:0046855]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of dephosphorylation [GO:0035305]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of glycogen (starch) synthase activity [GO:2000466]; negative regulation of glycogen biosynthetic process [GO:0045719]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein targeting to membrane [GO:0090315]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of stress fiber assembly [GO:0051497]; phosphatidylinositol dephosphorylation [GO:0046856]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of renal water transport [GO:2001153]; positive regulation of urine volume [GO:0035810]; protein localization to plasma membrane [GO:0072659]; regulation of glycogen biosynthetic process [GO:0005979]; response to insulin [GO:0032868]; ruffle assembly [GO:0097178] GO:0001701; GO:0001726; GO:0001933; GO:0004439; GO:0004445; GO:0005000; GO:0005634; GO:0005737; GO:0005783; GO:0005802; GO:0005829; GO:0005886; GO:0005979; GO:0006469; GO:0007186; GO:0010801; GO:0010829; GO:0016020; GO:0016311; GO:0016312; GO:0032587; GO:0032868; GO:0032869; GO:0032870; GO:0033137; GO:0034485; GO:0034594; GO:0034595; GO:0035305; GO:0035810; GO:0042593; GO:0043005; GO:0043407; GO:0043922; GO:0045719; GO:0045869; GO:0045892; GO:0045893; GO:0046030; GO:0046627; GO:0046855; GO:0046856; GO:0048471; GO:0051497; GO:0051898; GO:0051926; GO:0052658; GO:0052659; GO:0071320; GO:0071356; GO:0071364; GO:0072659; GO:0090315; GO:0097178; GO:2000466; GO:2001153 22867 XM_029358326.2 7741 4844 3750 6019 3089 Q99M51 5.53e-80 Cytoplasmic protein NCK1 (NCK adaptor protein 1) (Nck-1) Mus musculus (Mouse) actin filament organization [GO:0007015]; cell migration [GO:0016477]; ephrin receptor signaling pathway [GO:0048013]; lamellipodium assembly [GO:0030032]; negative regulation of cell death [GO:0060548]; negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation [GO:1903912]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990441]; peptidyl-serine dephosphorylation [GO:0070262]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cap-dependent translational initiation [GO:1903676]; positive regulation of cap-independent translational initiation [GO:1903679]; positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902237]; positive regulation of neuron projection development [GO:0010976]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translation in response to endoplasmic reticulum stress [GO:0036493]; regulation of cell migration [GO:0030334]; response to other organism [GO:0051707]; signal transduction [GO:0007165]; substrate-dependent cell migration, cell extension [GO:0006930]; T cell activation [GO:0042110] GO:0000164; GO:0004860; GO:0005102; GO:0005634; GO:0005737; GO:0005783; GO:0005829; GO:0005840; GO:0005886; GO:0005911; GO:0006930; GO:0007015; GO:0007165; GO:0010976; GO:0012506; GO:0016477; GO:0019904; GO:0030032; GO:0030334; GO:0030674; GO:0030838; GO:0030971; GO:0033137; GO:0035591; GO:0036493; GO:0042102; GO:0042110; GO:0045944; GO:0046627; GO:0046875; GO:0048013; GO:0051707; GO:0060548; GO:0070262; GO:0071074; GO:0140693; GO:1902237; GO:1903676; GO:1903679; GO:1903898; GO:1903912; GO:1990441 22868 XM_044320543.1 0 0 12 0 14 NA NA NA NA NA NA 22869 XM_044317024.1 68 0 0 41 44 P54131 6.64e-90 Neuronal acetylcholine receptor subunit alpha-7 Bos taurus (Bovine) calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; cognition [GO:0050890]; ion transmembrane transport [GO:0034220]; negative regulation of tumor necrosis factor production [GO:0032720]; nervous system process [GO:0050877]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAPK cascade [GO:0043410]; regulation of membrane potential [GO:0042391]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271] GO:0001540; GO:0001666; GO:0005231; GO:0005886; GO:0005892; GO:0006816; GO:0006874; GO:0007165; GO:0007268; GO:0007271; GO:0008284; GO:0015464; GO:0015643; GO:0017081; GO:0022848; GO:0030594; GO:0032720; GO:0034220; GO:0035094; GO:0042166; GO:0042391; GO:0042803; GO:0043005; GO:0043410; GO:0045202; GO:0045211; GO:0045766; GO:0050877; GO:0050890; GO:1904315 22870 XR_006397163.1 47 79 32 39 83 NA NA NA NA NA NA 22871 XM_029346829.2 0 10 22 0 0 NA NA NA NA NA NA 22872 XM_044325523.1 158 0 0 0 0 O15439 0 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 22873 XM_029327159.2 88 118 143 343 0 NA NA NA NA NA NA 22874 XM_029349429.2 879 767 525 730 502 NA NA NA NA NA NA 22875 XR_006397333.1 1704 858 730 956 939 F1MNN4 3.99e-71 F-box/WD repeat-containing protein 7 (F-box and WD-40 domain-containing protein 7) Bos taurus (Bovine) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; lung development [GO:0030324]; negative regulation of gene expression [GO:0010629]; negative regulation of osteoclast development [GO:2001205]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; Notch signaling pathway [GO:0007219]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903378]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein destabilization [GO:0031648]; protein K63-linked ubiquitination [GO:0070534]; protein stabilization [GO:0050821]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of cell migration involved in sprouting angiogenesis [GO:0090049]; regulation of circadian rhythm [GO:0042752]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; sister chromatid cohesion [GO:0007062]; vasculogenesis [GO:0001570] GO:0001570; GO:0005654; GO:0005694; GO:0005730; GO:0005739; GO:0005783; GO:0006281; GO:0006886; GO:0006888; GO:0006890; GO:0006891; GO:0006974; GO:0007062; GO:0007219; GO:0010629; GO:0019005; GO:0030126; GO:0030324; GO:0030332; GO:0031146; GO:0031625; GO:0031648; GO:0042752; GO:0042802; GO:0045741; GO:0048471; GO:0050816; GO:0050821; GO:0051443; GO:0070374; GO:0070534; GO:0090049; GO:0097027; GO:1901800; GO:1903026; GO:1903146; GO:1903378; GO:1903955; GO:1990452; GO:1990756; GO:2000060; GO:2001205 22876 XR_006397333.1 1704 858 730 956 939 F1MNN4 6.94e-29 F-box/WD repeat-containing protein 7 (F-box and WD-40 domain-containing protein 7) Bos taurus (Bovine) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; lung development [GO:0030324]; negative regulation of gene expression [GO:0010629]; negative regulation of osteoclast development [GO:2001205]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; Notch signaling pathway [GO:0007219]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903378]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein destabilization [GO:0031648]; protein K63-linked ubiquitination [GO:0070534]; protein stabilization [GO:0050821]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of cell migration involved in sprouting angiogenesis [GO:0090049]; regulation of circadian rhythm [GO:0042752]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; sister chromatid cohesion [GO:0007062]; vasculogenesis [GO:0001570] GO:0001570; GO:0005654; GO:0005694; GO:0005730; GO:0005739; GO:0005783; GO:0006281; GO:0006886; GO:0006888; GO:0006890; GO:0006891; GO:0006974; GO:0007062; GO:0007219; GO:0010629; GO:0019005; GO:0030126; GO:0030324; GO:0030332; GO:0031146; GO:0031625; GO:0031648; GO:0042752; GO:0042802; GO:0045741; GO:0048471; GO:0050816; GO:0050821; GO:0051443; GO:0070374; GO:0070534; GO:0090049; GO:0097027; GO:1901800; GO:1903026; GO:1903146; GO:1903378; GO:1903955; GO:1990452; GO:1990756; GO:2000060; GO:2001205 22877 XM_044314596.1 1010 851 573 932 786 A2VDN5 2.27e-122 Spastin (EC 5.6.1.1) Bos taurus (Bovine) anterograde axonal transport [GO:0008089]; axonal transport of mitochondrion [GO:0019896]; axonogenesis [GO:0007409]; cytokinetic process [GO:0032506]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exit from mitosis [GO:0010458]; membrane fission [GO:0090148]; metabolic process [GO:0008152]; microtubule bundle formation [GO:0001578]; microtubule severing [GO:0051013]; mitotic cytokinesis [GO:0000281]; mitotic spindle disassembly [GO:0051228]; nuclear membrane reassembly [GO:0031468]; positive regulation of cytokinesis [GO:0032467]; positive regulation of microtubule depolymerization [GO:0031117]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260] GO:0000281; GO:0000922; GO:0001578; GO:0005524; GO:0005634; GO:0005654; GO:0005768; GO:0005783; GO:0005813; GO:0005829; GO:0005874; GO:0006888; GO:0007409; GO:0008017; GO:0008089; GO:0008152; GO:0008568; GO:0010458; GO:0015630; GO:0016853; GO:0016887; GO:0019896; GO:0030424; GO:0030496; GO:0031117; GO:0031468; GO:0031965; GO:0032467; GO:0032506; GO:0034214; GO:0043014; GO:0048471; GO:0048487; GO:0051013; GO:0051228; GO:0051260; GO:0090148; GO:1904115 22878 XR_006392939.1 41 2 25 5 151 NA NA NA NA NA NA 22879 XR_006398094.1 23 0 28 0 6 NA NA NA NA NA NA 22880 XM_029344582.2 1052 662 235 488 473 Q642F4 3.08e-67 Vesicle-trafficking protein SEC22a (SEC22 vesicle-trafficking protein homolog A) (SEC22 vesicle-trafficking protein-like 2) (rSec22a) Rattus norvegicus (Rat) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; protein transport [GO:0015031] GO:0005789; GO:0006888; GO:0015031; GO:0016020 22881 XM_029336146.2 197 240 219 0 290 P61460 0 GATOR complex protein DEPDC5 (DEP domain-containing protein 5) Mus musculus (Mouse) cellular response to amino acid starvation [GO:0034198]; intracellular signal transduction [GO:0035556]; negative regulation of TOR signaling [GO:0032007]; negative regulation of TORC1 signaling [GO:1904262]; positive regulation of autophagy [GO:0010508] GO:0005096; GO:0005764; GO:0005765; GO:0005829; GO:0010508; GO:0031463; GO:0032007; GO:0034198; GO:0035556; GO:0044877; GO:0048471; GO:1904262; GO:1990130 22882 XM_029336146.2 197 240 219 0 290 P61460 4.43e-53 GATOR complex protein DEPDC5 (DEP domain-containing protein 5) Mus musculus (Mouse) cellular response to amino acid starvation [GO:0034198]; intracellular signal transduction [GO:0035556]; negative regulation of TOR signaling [GO:0032007]; negative regulation of TORC1 signaling [GO:1904262]; positive regulation of autophagy [GO:0010508] GO:0005096; GO:0005764; GO:0005765; GO:0005829; GO:0010508; GO:0031463; GO:0032007; GO:0034198; GO:0035556; GO:0044877; GO:0048471; GO:1904262; GO:1990130 22883 XM_029341132.2 2450 2331 1127 1688 1633 A8Y5T1 2.72e-34 Protein CFAP276 (Cilia- and flagella-associated protein 276) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005737; GO:0005856; GO:0005879 22884 XR_006396462.1 83 0 27 116 10 Q99570 4.08e-23 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 22885 XM_029331720.2 122 96 106 313 129 Q8BZ20 2.96e-57 Protein mono-ADP-ribosyltransferase PARP12 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 12) (ARTD12) (Poly [ADP-ribose] polymerase 12) (PARP-12) (Zinc finger CCCH domain-containing protein 1) Mus musculus (Mouse) protein auto-ADP-ribosylation [GO:0070213] GO:0003950; GO:0005634; GO:0016779; GO:0046872; GO:0070213; GO:0140803; GO:1990404 22886 XM_044317616.1 26 17 39 23 56 Q06115 4.46e-27 Conjugated bile acid hydrolase (EC 3.5.1.-) (Bile salt hydrolase) (BSH) (Choloylglycine hydrolase) (EC 3.5.1.24) Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1) (Lactobacillus plantarum) bile acid biosynthetic process [GO:0006699] GO:0006699; GO:0045302; GO:0047742 22887 XM_029323589.2 2221 1364 1283 2518 2587 Q7L014 0 Probable ATP-dependent RNA helicase DDX46 (EC 3.6.4.13) (DEAD box protein 46) (PRP5 homolog) Homo sapiens (Human) mRNA splicing, via spliceosome [GO:0000398]; U2-type prespliceosome assembly [GO:1903241] GO:0000398; GO:0001650; GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005654; GO:0005681; GO:0005686; GO:0015030; GO:0016020; GO:0016607; GO:0016887; GO:1903241 22888 XM_044311564.1 0 2 12 1 28 NA NA NA NA NA NA 22889 XM_044326795.1 16 0 0 3 19 NA NA NA NA NA NA 22890 XM_044312281.1 0 3 1 8 0 Q5R5U3 1.49e-107 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 22891 XM_044312281.1 0 3 1 8 0 Q5R5U3 2.04e-106 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 22892 XM_044312281.1 0 3 1 8 0 Q5R5U3 4.69e-106 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 22893 XM_044312281.1 0 3 1 8 0 Q5R5U3 2.41e-100 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 22894 XM_044312281.1 0 3 1 8 0 Q5R5U3 2.5e-95 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 22895 XM_044312281.1 0 3 1 8 0 Q5R5U3 1.12e-72 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 22896 XM_044312281.1 0 3 1 8 0 Q5R5U3 1.1e-41 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 22897 XM_044323069.1 202 152 112 197 171 Q08DM8 1.68e-76 Translin (EC 3.1.-.-) (Component 3 of promoter of RISC) (C3PO) Bos taurus (Bovine) siRNA processing [GO:0030422] GO:0003697; GO:0003723; GO:0004519; GO:0005634; GO:0005654; GO:0005737; GO:0005783; GO:0030422; GO:0042802; GO:0043565; GO:1902555 22898 XM_029347870.2 5377 9884 4928 5313 4263 NA NA NA NA NA NA 22899 XM_044325522.1 19 22 43 108 77 O15439 0 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 22900 XM_029324624.2 88 23 73 84 96 Q9TTF0 3.48e-102 Photoreceptor-specific nuclear receptor (Nuclear receptor subfamily 2 group E member 3) (Retina-specific nuclear receptor) Bos taurus (Bovine) anatomical structure development [GO:0048856]; cell differentiation [GO:0030154]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000978; GO:0004879; GO:0005634; GO:0006357; GO:0008270; GO:0030154; GO:0045944; GO:0048856 22901 XM_029340957.2 0 0 281 0 0 Q6Y7W6 1.47e-24 GRB10-interacting GYF protein 2 (PERQ amino acid-rich with GYF domain-containing protein 2) (Trinucleotide repeat-containing gene 15 protein) Homo sapiens (Human) adult locomotory behavior [GO:0008344]; feeding behavior [GO:0007631]; homeostasis of number of cells within a tissue [GO:0048873]; insulin-like growth factor receptor signaling pathway [GO:0048009]; mitotic G1 DNA damage checkpoint signaling [GO:0031571]; mRNA destabilization [GO:0061157]; multicellular organism growth [GO:0035264]; musculoskeletal movement [GO:0050881]; negative regulation of translation [GO:0017148]; neuromuscular process controlling balance [GO:0050885]; post-embryonic development [GO:0009791]; post-transcriptional gene silencing [GO:0016441]; protein metabolic process [GO:0019538]; spinal cord motor neuron differentiation [GO:0021522] GO:0003723; GO:0005768; GO:0005783; GO:0005794; GO:0005829; GO:0007631; GO:0008344; GO:0009791; GO:0010494; GO:0016020; GO:0016441; GO:0017148; GO:0019538; GO:0021522; GO:0031571; GO:0031982; GO:0032991; GO:0035264; GO:0043204; GO:0045296; GO:0048009; GO:0048873; GO:0050881; GO:0050885; GO:0061157; GO:0070064; GO:1990635 22902 XM_029340957.2 0 0 281 0 0 Q6Y7W6 2.41e-23 GRB10-interacting GYF protein 2 (PERQ amino acid-rich with GYF domain-containing protein 2) (Trinucleotide repeat-containing gene 15 protein) Homo sapiens (Human) adult locomotory behavior [GO:0008344]; feeding behavior [GO:0007631]; homeostasis of number of cells within a tissue [GO:0048873]; insulin-like growth factor receptor signaling pathway [GO:0048009]; mitotic G1 DNA damage checkpoint signaling [GO:0031571]; mRNA destabilization [GO:0061157]; multicellular organism growth [GO:0035264]; musculoskeletal movement [GO:0050881]; negative regulation of translation [GO:0017148]; neuromuscular process controlling balance [GO:0050885]; post-embryonic development [GO:0009791]; post-transcriptional gene silencing [GO:0016441]; protein metabolic process [GO:0019538]; spinal cord motor neuron differentiation [GO:0021522] GO:0003723; GO:0005768; GO:0005783; GO:0005794; GO:0005829; GO:0007631; GO:0008344; GO:0009791; GO:0010494; GO:0016020; GO:0016441; GO:0017148; GO:0019538; GO:0021522; GO:0031571; GO:0031982; GO:0032991; GO:0035264; GO:0043204; GO:0045296; GO:0048009; GO:0048873; GO:0050881; GO:0050885; GO:0061157; GO:0070064; GO:1990635 22903 XR_006394448.1 40 0 0 31 0 NA NA NA NA NA NA 22904 XM_044318876.1 94 47 50 65 92 NA NA NA NA NA NA 22905 XM_029325130.2 8 5 0 0 0 NA NA NA NA NA NA 22906 XR_006392539.1 79 71 40 112 54 NA NA NA NA NA NA 22907 XM_029352969.2 248 225 493 370 554 NA NA NA NA NA NA 22908 XM_044312775.1 294 214 235 149 434 Q6DCF2 4.55e-174 MMS19 nucleotide excision repair protein homolog (MMS19-like protein) Xenopus laevis (African clawed frog) cellular response to DNA damage stimulus [GO:0006974]; DNA metabolic process [GO:0006259]; DNA repair [GO:0006281]; iron-sulfur cluster assembly [GO:0016226]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; protein maturation by iron-sulfur cluster transfer [GO:0097428] GO:0005634; GO:0005737; GO:0005819; GO:0006259; GO:0006281; GO:0006974; GO:0016226; GO:0097361; GO:0097428; GO:1905168 22909 XM_044308137.1 0 0 24 0 6 NA NA NA NA NA NA 22910 XM_029348382.2 27 0 3 0 0 NA NA NA NA NA NA 22911 XM_029336361.2 198 73 76 165 39 Q6DDJ5 2.99e-24 WD repeat and coiled-coil-containing protein Xenopus laevis (African clawed frog) NA NA 22912 XM_029348169.2 481 363 176 563 699 P63253 2.18e-74 Inward rectifier potassium channel 2 (Cardiac inward rectifier potassium channel) (Inward rectifier K(+) channel Kir2.1) (IRK-1) (Potassium channel, inwardly rectifying subfamily J member 2) Macaca mulatta (Rhesus macaque) cardiac muscle cell action potential involved in contraction [GO:0086002]; magnesium ion transport [GO:0015693]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transport [GO:0006813]; protein homotetramerization [GO:0051289]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane repolarization [GO:0060306]; regulation of skeletal muscle contraction via regulation of action potential [GO:0014861]; relaxation of cardiac muscle [GO:0055119]; relaxation of skeletal muscle [GO:0090076] GO:0005242; GO:0005546; GO:0005886; GO:0006813; GO:0008076; GO:0014861; GO:0015693; GO:0016020; GO:0034765; GO:0042802; GO:0051289; GO:0055119; GO:0060306; GO:0086002; GO:0086008; GO:0086091; GO:0090076; GO:1990573 22913 XM_044315776.1 375 798 333 197 34 NA NA NA NA NA NA 22914 XM_044308290.1 931 350 177 428 392 Q9D5I4 5.51e-22 Dynein light chain Tctex-type 5 (Tctex1 domain-containing protein 1) Mus musculus (Mouse) microtubule-based movement [GO:0007018] GO:0005737; GO:0005868; GO:0007018; GO:0045505 22915 XR_006391357.1 8 7 12 0 25 NA NA NA NA NA NA 22916 XM_044313540.1 342 261 121 105 249 NA NA NA NA NA NA 22917 XM_044318505.1 28 32 49 9 39 NA NA NA NA NA NA 22918 XM_044310802.1 89 246 58 67 27 NA NA NA NA NA NA 22919 XM_044324208.1 239 416 145 331 268 NA NA NA NA NA NA 22920 XR_003825864.2 9 31 36 11 77 NA NA NA NA NA NA 22921 XM_044321638.1 169 107 166 15 57 P49914 1.64e-68 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) (5,10-methenyl-tetrahydrofolate synthetase) (MTHFS) (Methenyl-THF synthetase) Homo sapiens (Human) folic acid catabolic process [GO:0046657]; folic acid metabolic process [GO:0046655]; folic acid-containing compound biosynthetic process [GO:0009396]; formate metabolic process [GO:0015942]; glutamate metabolic process [GO:0006536]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653] GO:0005524; GO:0005542; GO:0005737; GO:0005739; GO:0005759; GO:0005829; GO:0006536; GO:0009396; GO:0015942; GO:0030272; GO:0035999; GO:0046653; GO:0046655; GO:0046657; GO:0046872 22922 XM_029336271.2 347 117 216 301 147 NA NA NA NA NA NA 22923 XM_029339865.2 128 271 0 357 286 Q5RBM1 4.46e-129 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit) (Ribophorin II) (RPN-II) (Ribophorin-2) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) protein N-linked glycosylation [GO:0006487] GO:0006487; GO:0008250 22924 XM_044307993.1 0 17 21 4 0 NA NA NA NA NA NA 22925 XR_006396896.1 14 1 0 0 0 NA NA NA NA NA NA 22926 XM_044320761.1 21 9 3 4 1 NA NA NA NA NA NA 22927 XM_044314215.1 0 0 19 0 3 NA NA NA NA NA NA 22928 XM_029354957.2 120 16 39 33 16 NA NA NA NA NA NA 22929 XM_029324312.2 161 164 0 47 42 NA NA NA NA NA NA 22930 XM_044323992.1 163 126 9 50 63 NA NA NA NA NA NA 22931 XR_006393513.1 69 27 0 44 60 NA NA NA NA NA NA 22932 XM_044307442.1 10 0 4 6 21 Q9TV36 1.55e-24 Fibrillin-1 [Cleaved into: Asprosin] Sus scrofa (Pig) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 22933 XM_029333866.2 1036 518 1248 532 3542 NA NA NA NA NA NA 22934 XM_044309417.1 14 0 0 0 0 NA NA NA NA NA NA 22935 XM_029354005.2 115 65 71 79 41 NA NA NA NA NA NA 22936 XM_029333507.2 593 397 301 237 465 Q6GMF8 8.79e-52 Inactive rhomboid protein 1 (iRhom1) (Rhomboid family member 1) Danio rerio (Zebrafish) (Brachydanio rerio) cell migration [GO:0016477]; cell population proliferation [GO:0008283]; negative regulation of protein secretion [GO:0050709]; protein transport [GO:0015031]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of protein secretion [GO:0050708] GO:0000139; GO:0005789; GO:0008283; GO:0015031; GO:0016477; GO:0019838; GO:0042058; GO:0050708; GO:0050709; GO:0061136 22937 XM_044324923.1 13 0 0 5 13 A2AJ77 3.4e-110 PR domain zinc finger protein 12 (EC 2.1.1.-) (PR domain-containing protein 12) Mus musculus (Mouse) detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; neuron projection development [GO:0031175]; positive regulation of histone H3-K9 dimethylation [GO:1900111]; protein methylation [GO:0006479]; regulation of gene expression [GO:0010468]; sensory perception of pain [GO:0019233] GO:0000122; GO:0003677; GO:0005634; GO:0005654; GO:0006479; GO:0008168; GO:0010468; GO:0019233; GO:0022008; GO:0031175; GO:0046872; GO:0050965; GO:0140713; GO:1900111; GO:1990226 22938 XM_044325405.1 344 253 372 498 488 P14740 7.33e-153 Dipeptidyl peptidase 4 (EC 3.4.14.5) (Bile canaliculus domain-specific membrane glycoprotein) (Dipeptidyl peptidase IV) (DPP IV) (GP110 glycoprotein) (T-cell activation antigen CD26) (CD antigen CD26) [Cleaved into: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form); Dipeptidyl peptidase 4 60 kDa soluble form (Dipeptidyl peptidase IV 60 kDa soluble form)] Rattus norvegicus (Rat) B-1a B cell differentiation [GO:0002337]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; establishment of localization [GO:0051234]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; negative regulation of neutrophil chemotaxis [GO:0090024]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of natural killer cell mediated immunity [GO:0002717]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of T cell mediated immunity [GO:0002709]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295] GO:0001618; GO:0001662; GO:0001666; GO:0002020; GO:0002337; GO:0002709; GO:0002717; GO:0004177; GO:0004252; GO:0005102; GO:0005518; GO:0005576; GO:0005783; GO:0005794; GO:0005886; GO:0006508; GO:0007155; GO:0008236; GO:0008239; GO:0008284; GO:0009986; GO:0010716; GO:0016324; GO:0030027; GO:0030139; GO:0030163; GO:0031258; GO:0031295; GO:0033632; GO:0035641; GO:0036343; GO:0042110; GO:0042277; GO:0042802; GO:0042803; GO:0043542; GO:0045121; GO:0045499; GO:0046581; GO:0051234; GO:0090024 22939 XM_044322539.1 0 39 3 89 24 O70624 1.51e-44 Myocilin (Trabecular meshwork-induced glucocorticoid response protein) [Cleaved into: Myocilin, N-terminal fragment (Myocilin 20 kDa N-terminal fragment); Myocilin, C-terminal fragment (Myocilin 35 kDa N-terminal fragment)] Mus musculus (Mouse) bone development [GO:0060348]; clustering of voltage-gated sodium channels [GO:0045162]; ERBB2-ERBB3 signaling pathway [GO:0038133]; myelination in peripheral nervous system [GO:0022011]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of stress fiber assembly [GO:0051497]; neuron projection development [GO:0031175]; non-canonical Wnt signaling pathway via JNK cascade [GO:0038031]; osteoblast differentiation [GO:0001649]; positive regulation of cell migration [GO:0030335]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of MAPK cascade [GO:0043408]; signal transduction [GO:0007165]; skeletal muscle hypertrophy [GO:0014734] GO:0001649; GO:0001953; GO:0001968; GO:0005109; GO:0005615; GO:0005737; GO:0005741; GO:0005743; GO:0005758; GO:0005783; GO:0005791; GO:0005794; GO:0005929; GO:0007165; GO:0014068; GO:0014734; GO:0022011; GO:0030335; GO:0030971; GO:0031175; GO:0031410; GO:0032027; GO:0033268; GO:0035024; GO:0035748; GO:0038031; GO:0038133; GO:0043220; GO:0043408; GO:0045162; GO:0046872; GO:0051496; GO:0051497; GO:0051894; GO:0051897; GO:0051901; GO:0060348; GO:0062023; GO:0070062; GO:0097453; GO:1900026 22940 XM_044325843.1 40 47 0 7 23 NA NA NA NA NA NA 22941 XM_029343273.2 78 84 8 70 42 NA NA NA NA NA NA 22942 XM_029358130.2 1398 572 405 1014 905 Q58DQ5 6.83e-38 28S ribosomal protein S9, mitochondrial (MRP-S9) (S9mt) Bos taurus (Bovine) translation [GO:0006412] GO:0003723; GO:0003735; GO:0005743; GO:0005763; GO:0006412; GO:0015935 22943 XR_006391542.1 0 1 10 0 0 NA NA NA NA NA NA 22944 XR_006397679.1 2 7 1 0 10 NA NA NA NA NA NA 22945 XM_044319814.1 0 3 10 0 14 Q8BHL6 4.97e-31 Fanconi anemia core complex-associated protein 24 (Fanconi anemia-associated protein of 24 kDa) Mus musculus (Mouse) interstrand cross-link repair [GO:0036297] GO:0000785; GO:0003677; GO:0003682; GO:0005654; GO:0036297; GO:0043231; GO:0043240; GO:0071821 22946 XM_044308118.1 135 0 34 101 189 NA NA NA NA NA NA 22947 XM_044308913.1 0 0 0 21 0 NA NA NA NA NA NA 22948 XR_006396778.1 23336 122697 205800 75286 62458 NA NA NA NA NA NA 22949 XM_044317057.1 91 82 52 27 52 Q4KM64 1.69e-27 Protein jagunal homolog 1 Rattus norvegicus (Rat) cellular response to organic substance [GO:0071310]; defense response to fungus [GO:0050832]; endoplasmic reticulum organization [GO:0007029]; granulocyte colony-stimulating factor signaling pathway [GO:0038158]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; neutrophil differentiation [GO:0030223]; neutrophil mediated immunity [GO:0002446]; neutrophil migration [GO:1990266]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] GO:0002446; GO:0005783; GO:0005789; GO:0007029; GO:0015031; GO:0016192; GO:0030223; GO:0038158; GO:0050832; GO:0061179; GO:0071310; GO:1990266 22950 XR_006393286.1 26 13 4 3 38 NA NA NA NA NA NA 22951 XM_029325151.2 271 105 126 189 159 A7SLX5 0 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 (EC 2.5.1.108) (Diphthamide biosynthesis protein 1) (Diphtheria toxin resistance protein 1) (S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1) Nematostella vectensis (Starlet sea anemone) peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183] GO:0017183; GO:0032991; GO:0046872; GO:0051539; GO:0090560 22952 XM_029346918.2 57 37 0 20 0 Q6GMF8 1.14e-155 Inactive rhomboid protein 1 (iRhom1) (Rhomboid family member 1) Danio rerio (Zebrafish) (Brachydanio rerio) cell migration [GO:0016477]; cell population proliferation [GO:0008283]; negative regulation of protein secretion [GO:0050709]; protein transport [GO:0015031]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of protein secretion [GO:0050708] GO:0000139; GO:0005789; GO:0008283; GO:0015031; GO:0016477; GO:0019838; GO:0042058; GO:0050708; GO:0050709; GO:0061136 22953 XM_044309561.1 9 3 26 2 45 A5D7F5 2.31e-37 DnaJ homolog subfamily C member 27 (Rab and DnaJ domain-containing protein) Bos taurus (Bovine) intracellular protein transport [GO:0006886] GO:0003924; GO:0005525; GO:0005634; GO:0006886 22954 XM_044328025.1 144 283 106 62 51 Q8K2J9 7.74e-72 BTB/POZ domain-containing protein 6 Mus musculus (Mouse) neurogenesis [GO:0022008] GO:0005829; GO:0022008 22955 XM_029334748.2 314 169 147 169 229 O95833 4.07e-23 Chloride intracellular channel protein 3 Homo sapiens (Human) chloride transport [GO:0006821]; regulation of ion transmembrane transport [GO:0034765]; signal transduction [GO:0007165] GO:0005244; GO:0005254; GO:0005634; GO:0005737; GO:0006821; GO:0007165; GO:0016020; GO:0016604; GO:0034707; GO:0034765; GO:0070062 22956 XM_029332904.2 797 416 468 459 200 Q9ULI0 0 ATPase family AAA domain-containing protein 2B Homo sapiens (Human) positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0003682; GO:0005524; GO:0005634; GO:0005654; GO:0016887; GO:0042393; GO:0045944; GO:0070577 22957 XM_044311185.1 1022 573 652 995 1396 NA NA NA NA NA NA 22958 XM_044308649.1 64 50 21 83 75 NA NA NA NA NA NA 22959 XM_029351913.2 541 786 567 919 1364 Q99NH2 1.27e-58 Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP) Mus musculus (Mouse) apical constriction [GO:0003383]; bicellular tight junction assembly [GO:0070830]; cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell-cell adhesion [GO:0098609]; centrosome localization [GO:0051642]; establishment of cell polarity [GO:0030010]; establishment of centrosome localization [GO:0051660]; establishment of epithelial cell polarity [GO:0090162]; establishment or maintenance of cell polarity [GO:0007163]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; microtubule cytoskeleton organization [GO:0000226]; myelination in peripheral nervous system [GO:0022011]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; positive regulation of myelination [GO:0031643]; positive regulation of receptor internalization [GO:0002092]; protein localization [GO:0008104]; protein targeting to membrane [GO:0006612]; regulation of actin filament-based process [GO:0032970]; regulation of cellular localization [GO:0060341]; wound healing, spreading of cells [GO:0044319] GO:0000226; GO:0002092; GO:0003383; GO:0005546; GO:0005547; GO:0005737; GO:0005819; GO:0005886; GO:0005911; GO:0005912; GO:0005923; GO:0005938; GO:0006612; GO:0007049; GO:0007155; GO:0007163; GO:0008104; GO:0010801; GO:0012505; GO:0016324; GO:0019903; GO:0022011; GO:0030010; GO:0030054; GO:0031643; GO:0032266; GO:0032970; GO:0032991; GO:0033269; GO:0035091; GO:0042802; GO:0043025; GO:0043219; GO:0043220; GO:0043296; GO:0044295; GO:0044319; GO:0045197; GO:0051301; GO:0051642; GO:0051660; GO:0060341; GO:0070830; GO:0090162; GO:0098609; GO:0120157 22960 XM_044318551.1 255 0 0 46 52 Q9M390 5.18e-85 Protein NRT1/ PTR FAMILY 8.1 (AtNPF8.1) (Peptide transporter PTR1) Arabidopsis thaliana (Mouse-ear cress) dipeptide transport [GO:0042938]; nitrogen compound metabolic process [GO:0006807]; protein transport [GO:0015031]; transmembrane transport [GO:0055085]; tripeptide transport [GO:0042939] GO:0005886; GO:0006807; GO:0009506; GO:0015031; GO:0016020; GO:0022857; GO:0042937; GO:0042938; GO:0042939; GO:0055085; GO:0071916 22961 XM_029343822.2 0 4 0 32 26 NA NA NA NA NA NA 22962 XM_044308414.1 109 54 105 148 114 Q54PI5 2.95e-39 Probable gluconokinase (EC 2.7.1.12) (Gluconate kinase) Dictyostelium discoideum (Social amoeba) D-gluconate catabolic process [GO:0046177]; phosphorylation [GO:0016310] GO:0005524; GO:0016310; GO:0046177; GO:0046316 22963 XR_006397324.1 320 86 100 109 71 NA NA NA NA NA NA 22964 XM_044324628.1 79 25 118 17 199 NA NA NA NA NA NA 22965 XM_029345756.2 533 608 553 804 971 NA NA NA NA NA NA 22966 XM_044317231.1 21 18 0 11 9 Q9CPW0 5.14e-23 Contactin-associated protein-like 2 (Cell recognition molecule Caspr2) Mus musculus (Mouse) action potential initiation [GO:0099610]; adult behavior [GO:0030534]; associative learning [GO:0008306]; axonogenesis [GO:0007409]; behavioral response to pain [GO:0048266]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell population proliferation [GO:0008283]; central nervous system myelination [GO:0022010]; cerebellar Purkinje cell layer morphogenesis [GO:0021692]; cerebellum development [GO:0021549]; chemical synaptic transmission [GO:0007268]; circadian sleep/wake cycle [GO:0042745]; clustering of voltage-gated potassium channels [GO:0045163]; dendrite arborization [GO:0140059]; dendritic spine development [GO:0060996]; dendritic spine maintenance [GO:0097062]; dendritic spine organization [GO:0097061]; embryonic brain development [GO:1990403]; ERK1 and ERK2 cascade [GO:0070371]; excitatory chemical synaptic transmission [GO:0098976]; excitatory postsynaptic potential [GO:0060079]; excitatory synapse assembly [GO:1904861]; fat cell differentiation [GO:0045444]; gene expression [GO:0010467]; glial cell proliferation [GO:0014009]; glutamatergic neuron differentiation [GO:1905962]; grooming behavior [GO:0007625]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; inhibitory chemical synaptic transmission [GO:0098977]; inhibitory synapse assembly [GO:1904862]; intracellular signal transduction [GO:0035556]; learning [GO:0007612]; limbic system development [GO:0021761]; locomotor rhythm [GO:0045475]; locomotory behavior [GO:0007626]; maintenance of synapse structure [GO:0099558]; mitochondrion organization [GO:0007005]; motor behavior [GO:0061744]; multicellular organism growth [GO:0035264]; myelination [GO:0042552]; negative regulation of neuronal action potential [GO:1904456]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; neural precursor cell proliferation [GO:0061351]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process [GO:0050905]; neuromuscular process controlling posture [GO:0050884]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuron recognition [GO:0008038]; neuronal action potential [GO:0019228]; positive regulation of gap junction assembly [GO:1903598]; positive regulation of neuronal action potential [GO:1904457]; postsynaptic density organization [GO:0097106]; protein kinase B signaling [GO:0043491]; protein localization [GO:0008104]; protein localization to juxtaparanode region of axon [GO:0071205]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; response to dietary excess [GO:0002021]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to interleukin-17 [GO:0097396]; response to light intensity [GO:0009642]; response to mechanical stimulus [GO:0009612]; response to metformin [GO:1901558]; response to odorant [GO:1990834]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; rhythmic behavior [GO:0007622]; social behavior [GO:0035176]; TOR signaling [GO:0031929]; transmission of nerve impulse [GO:0019226]; vocal learning [GO:0042297]; vocalization behavior [GO:0071625]; walking behavior [GO:0090659] GO:0000902; GO:0001701; GO:0002021; GO:0005769; GO:0005794; GO:0006954; GO:0007005; GO:0007155; GO:0007268; GO:0007409; GO:0007612; GO:0007622; GO:0007625; GO:0007626; GO:0008038; GO:0008076; GO:0008104; GO:0008283; GO:0008306; GO:0009408; GO:0009410; GO:0009612; GO:0009642; GO:0009725; GO:0009986; GO:0010033; GO:0010467; GO:0014009; GO:0016020; GO:0019226; GO:0019228; GO:0019899; GO:0021549; GO:0021692; GO:0021761; GO:0022010; GO:0030165; GO:0030424; GO:0030425; GO:0030534; GO:0030673; GO:0031175; GO:0031929; GO:0032229; GO:0033010; GO:0035176; GO:0035264; GO:0035556; GO:0042297; GO:0042552; GO:0042734; GO:0042745; GO:0043005; GO:0043025; GO:0043194; GO:0043491; GO:0044224; GO:0044309; GO:0044853; GO:0045163; GO:0045202; GO:0045444; GO:0045475; GO:0048265; GO:0048266; GO:0048787; GO:0048812; GO:0050884; GO:0050905; GO:0060076; GO:0060079; GO:0060996; GO:0061351; GO:0061744; GO:0070371; GO:0071205; GO:0071625; GO:0090659; GO:0097061; GO:0097062; GO:0097106; GO:0097396; GO:0098529; GO:0098793; GO:0098794; GO:0098976; GO:0098977; GO:0098978; GO:0098982; GO:0099072; GO:0099558; GO:0099610; GO:0140059; GO:0150048; GO:1901558; GO:1903598; GO:1904456; GO:1904457; GO:1904861; GO:1904862; GO:1905962; GO:1990403; GO:1990834 22967 XM_044311580.1 33 40 36 40 41 NA NA NA NA NA NA 22968 XM_029356734.2 470 386 356 379 409 Q3SWZ6 1.25e-130 Ribosome maturation protein SBDS (Shwachman-Bodian-Diamond syndrome protein homolog) Bos taurus (Bovine) bone marrow development [GO:0048539]; bone mineralization [GO:0030282]; cytosolic ribosome assembly [GO:0042256]; hematopoietic progenitor cell differentiation [GO:0002244]; inner cell mass cell proliferation [GO:0001833]; leukocyte chemotaxis [GO:0030595]; mitotic spindle organization [GO:0007052]; rRNA processing [GO:0006364] GO:0000922; GO:0001833; GO:0002244; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0006364; GO:0007052; GO:0008017; GO:0019843; GO:0030282; GO:0030595; GO:0042256; GO:0043022; GO:0048539 22969 XR_006393155.1 446 403 497 602 483 NA NA NA NA NA NA 22970 XM_044315191.1 5 0 13 11 14 NA NA NA NA NA NA 22971 XR_006396377.1 35 9 6 0 27 NA NA NA NA NA NA 22972 XM_029342603.2 0 281 0 53 53 Q9VBW3 2.9e-85 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 22973 XR_006397092.1 0 30 11 1 21 NA NA NA NA NA NA 22974 XR_006395457.1 16 0 18 0 85 NA NA NA NA NA NA 22975 XR_006393763.1 136 163 256 691 367 NA NA NA NA NA NA 22976 XM_029342251.2 79 57 59 122 123 C3ZQF9 1.96e-25 QRFP-like peptide receptor Branchiostoma floridae (Florida lancelet) (Amphioxus) cellular response to peptide [GO:1901653]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:1901653 22977 XM_044313093.1 210 73 71 253 190 NA NA NA NA NA NA 22978 XM_044314237.1 123 579 252 140 539 A0A2P1BRQ0 2.28e-76 Cytolytic toxin-alpha (Sp-CTx-alpha) Scorpaena plumieri (Spotted scorpionfish) hemolysis in another organism [GO:0044179] GO:0005576; GO:0044179; GO:0090729 22979 XM_029328788.2 141 0 0 28 122 Q8R2J9 1.45e-128 DNA repair protein RAD51 homolog 3 (R51H3) (RAD51 homolog C) (RAD51-like protein 2) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) DNA recombination [GO:0006310]; DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; female meiosis sister chromatid cohesion [GO:0007066]; male meiosis I [GO:0007141]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; reciprocal meiotic recombination [GO:0007131]; sister chromatid cohesion [GO:0007062]; spermatogenesis [GO:0007283]; telomere maintenance via recombination [GO:0000722] GO:0000400; GO:0000722; GO:0000724; GO:0005524; GO:0005634; GO:0005654; GO:0005657; GO:0005737; GO:0005739; GO:0005829; GO:0006281; GO:0006310; GO:0007062; GO:0007066; GO:0007131; GO:0007141; GO:0007283; GO:0008821; GO:0010971; GO:0030054; GO:0033063; GO:0033065; GO:0048471; GO:0048476; GO:0140664 22980 XM_029357640.2 1027 136 1195 40 143 NA NA NA NA NA NA 22981 XR_003828609.2 14 15 12 5 21 NA NA NA NA NA NA 22982 XM_029338564.2 222 134 79 169 166 Q80UM7 0 Mannosyl-oligosaccharide glucosidase (EC 3.2.1.106) (Glucosidase 1) (Glycoprotein-processing glucosidase I) Mus musculus (Mouse) oligosaccharide metabolic process [GO:0009311]; protein N-linked glycosylation [GO:0006487] GO:0004573; GO:0005783; GO:0005789; GO:0006487; GO:0009311 22983 XM_029335098.2 0 0 9 0 0 NA NA NA NA NA NA 22984 XM_029337845.2 275 427 526 652 136 NA NA NA NA NA NA 22985 XM_029349181.2 101 42 30 56 29 O15439 0 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 22986 XM_029358207.2 295 341 189 351 348 Q5T5N4 2.74e-21 Uncharacterized protein C6orf118 Homo sapiens (Human) NA NA 22987 XM_029346595.2 880 999 892 656 669 Q32KL4 1.63e-41 Regulator of microtubule dynamics protein 1 (RMD-1) (Protein FAM82B) Bos taurus (Bovine) NA GO:0005737; GO:0005876; GO:0008017; GO:0097431 22988 XM_044313549.1 54 10 36 80 93 NA NA NA NA NA NA 22989 XM_029331978.2 28 17 0 86 84 B0G143 4.81e-68 Mitochondrial substrate carrier family protein ucpB (Solute carrier family 25 member 30 homolog) (Uncoupler protein B) Dictyostelium discoideum (Social amoeba) mitochondrial transport [GO:0006839] GO:0005743; GO:0006839; GO:0022857 22990 XR_006397227.1 0 0 107 36 0 NA NA NA NA NA NA 22991 XM_029330072.2 24 0 36 49 0 P48728 3.63e-147 Aminomethyltransferase, mitochondrial (EC 2.1.2.10) (Glycine cleavage system T protein) (GCVT) Homo sapiens (Human) glycine catabolic process [GO:0006546]; glycine decarboxylation via glycine cleavage system [GO:0019464] GO:0004047; GO:0005654; GO:0005739; GO:0005759; GO:0006546; GO:0008483; GO:0019464 22992 XM_044319137.1 530 312 0 89 33 NA NA NA NA NA NA 22993 XM_029340165.2 0 14 200 108 42 NA NA NA NA NA NA 22994 XM_029358601.2 1809 2807 2452 4537 5031 Q6TMK8 3.61e-58 PRELI domain containing protein 3B (BCR/ABL-regulated protein) (Protein slowmo homolog 2) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) NA GO:0005758 22995 XM_044314154.1 37 64 25 19 17 O46374 6.15e-41 DNA topoisomerase 2-alpha (EC 5.6.2.2) (DNA topoisomerase II, alpha isozyme) Sus scrofa (Pig) apoptotic chromosome condensation [GO:0030263]; cellular response to DNA damage stimulus [GO:0006974]; DNA ligation [GO:0006266]; DNA topological change [GO:0006265]; embryonic cleavage [GO:0040016]; female meiotic nuclear division [GO:0007143]; hematopoietic progenitor cell differentiation [GO:0002244]; negative regulation of DNA duplex unwinding [GO:1905463]; positive regulation of apoptotic process [GO:0043065]; positive regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045870]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of circadian rhythm [GO:0042752]; resolution of meiotic recombination intermediates [GO:0000712]; rhythmic process [GO:0048511]; sister chromatid segregation [GO:0000819] GO:0000228; GO:0000287; GO:0000712; GO:0000775; GO:0000793; GO:0000819; GO:0001673; GO:0002244; GO:0003682; GO:0003918; GO:0005080; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005814; GO:0006265; GO:0006266; GO:0006974; GO:0007143; GO:0008022; GO:0008301; GO:0009330; GO:0030263; GO:0040016; GO:0042752; GO:0042803; GO:0042826; GO:0043065; GO:0043130; GO:0045870; GO:0045944; GO:0046982; GO:0048511; GO:1905463; GO:1990904 22996 XM_029327763.2 0 0 0 3 46 NA NA NA NA NA NA 22997 XM_044328644.1 0 0 27 29 94 P46023 2.36e-113 G-protein coupled receptor GRL101 Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004930; GO:0005886 22998 XM_029327120.2 402 212 79 326 137 NA NA NA NA NA NA 22999 XR_006394870.1 21 0 0 33 47 NA NA NA NA NA NA 23000 XM_029325566.2 1901 530 1006 1821 2229 O00468 8.35e-44 Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment (C90); Agrin C-terminal 22 kDa fragment (C22)] Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; clustering of voltage-gated sodium channels [GO:0045162]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; neuromuscular junction development [GO:0007528]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of synaptic assembly at neuromuscular junction [GO:0045887]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor clustering [GO:0043113]; signal transduction [GO:0007165]; synapse organization [GO:0050808]; tissue development [GO:0009888] GO:0002162; GO:0005200; GO:0005509; GO:0005576; GO:0005604; GO:0005796; GO:0005886; GO:0007165; GO:0007213; GO:0007528; GO:0009887; GO:0009888; GO:0033691; GO:0035374; GO:0043113; GO:0043202; GO:0043236; GO:0043395; GO:0043547; GO:0045162; GO:0045202; GO:0045887; GO:0045944; GO:0050808; GO:0051491; GO:0062023; GO:0070062 23001 XM_029325566.2 1901 530 1006 1821 2229 O00468 6.03e-40 Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment (C90); Agrin C-terminal 22 kDa fragment (C22)] Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; clustering of voltage-gated sodium channels [GO:0045162]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; neuromuscular junction development [GO:0007528]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of synaptic assembly at neuromuscular junction [GO:0045887]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor clustering [GO:0043113]; signal transduction [GO:0007165]; synapse organization [GO:0050808]; tissue development [GO:0009888] GO:0002162; GO:0005200; GO:0005509; GO:0005576; GO:0005604; GO:0005796; GO:0005886; GO:0007165; GO:0007213; GO:0007528; GO:0009887; GO:0009888; GO:0033691; GO:0035374; GO:0043113; GO:0043202; GO:0043236; GO:0043395; GO:0043547; GO:0045162; GO:0045202; GO:0045887; GO:0045944; GO:0050808; GO:0051491; GO:0062023; GO:0070062 23002 XM_029325566.2 1901 530 1006 1821 2229 O00468 2.94e-34 Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment (C90); Agrin C-terminal 22 kDa fragment (C22)] Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; clustering of voltage-gated sodium channels [GO:0045162]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; neuromuscular junction development [GO:0007528]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of synaptic assembly at neuromuscular junction [GO:0045887]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor clustering [GO:0043113]; signal transduction [GO:0007165]; synapse organization [GO:0050808]; tissue development [GO:0009888] GO:0002162; GO:0005200; GO:0005509; GO:0005576; GO:0005604; GO:0005796; GO:0005886; GO:0007165; GO:0007213; GO:0007528; GO:0009887; GO:0009888; GO:0033691; GO:0035374; GO:0043113; GO:0043202; GO:0043236; GO:0043395; GO:0043547; GO:0045162; GO:0045202; GO:0045887; GO:0045944; GO:0050808; GO:0051491; GO:0062023; GO:0070062 23003 XM_044314300.1 0 5 9 9 3 NA NA NA NA NA NA 23004 XR_006398160.1 4 0 6 0 49 NA NA NA NA NA NA 23005 XM_044309703.1 19 4 37 40 91 Q96AY4 3.83e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23006 XM_029335915.2 5 4 7 2 23 NA NA NA NA NA NA 23007 XM_044306875.1 33 186 0 0 26 Q15858 0 Sodium channel protein type 9 subunit alpha (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1) (PN1) (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) Homo sapiens (Human) behavioral response to formalin induced pain [GO:0061368]; circadian rhythm [GO:0007623]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; inflammatory response [GO:0006954]; membrane depolarization during action potential [GO:0086010]; negative regulation of action potential [GO:0045759]; neuronal action potential [GO:0019228]; post-embryonic development [GO:0009791]; regulation of ion transmembrane transport [GO:0034765]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to toxic substance [GO:0009636]; sensory perception of pain [GO:0019233]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814] GO:0001518; GO:0005244; GO:0005248; GO:0005886; GO:0006814; GO:0006954; GO:0007623; GO:0009408; GO:0009409; GO:0009636; GO:0009791; GO:0019228; GO:0019233; GO:0030424; GO:0031402; GO:0034765; GO:0035725; GO:0045759; GO:0050965; GO:0050974; GO:0061368; GO:0086010 23008 XM_044306875.1 33 186 0 0 26 Q15858 2.12e-67 Sodium channel protein type 9 subunit alpha (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1) (PN1) (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) Homo sapiens (Human) behavioral response to formalin induced pain [GO:0061368]; circadian rhythm [GO:0007623]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; inflammatory response [GO:0006954]; membrane depolarization during action potential [GO:0086010]; negative regulation of action potential [GO:0045759]; neuronal action potential [GO:0019228]; post-embryonic development [GO:0009791]; regulation of ion transmembrane transport [GO:0034765]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to toxic substance [GO:0009636]; sensory perception of pain [GO:0019233]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814] GO:0001518; GO:0005244; GO:0005248; GO:0005886; GO:0006814; GO:0006954; GO:0007623; GO:0009408; GO:0009409; GO:0009636; GO:0009791; GO:0019228; GO:0019233; GO:0030424; GO:0031402; GO:0034765; GO:0035725; GO:0045759; GO:0050965; GO:0050974; GO:0061368; GO:0086010 23009 XR_006393176.1 21 29 64 203 61 NA NA NA NA NA NA 23010 XM_044321492.1 58 4 25 5 124 NA NA NA NA NA NA 23011 XM_029344630.2 0 507 0 474 516 NA NA NA NA NA NA 23012 XR_006397213.1 15 8 7 65 74 NA NA NA NA NA NA 23013 XM_044318375.1 0 0 0 0 21 NA NA NA NA NA NA 23014 XM_029338488.2 82 113 179 90 0 Q6DDL7 1.35e-141 Protein unc-93 homolog A (Unc-93A) Xenopus laevis (African clawed frog) NA GO:0016020 23015 XM_029338690.2 1057 393 347 724 302 NA NA NA NA NA NA 23016 XM_044316225.1 5 0 8 16 88 NA NA NA NA NA NA 23017 XM_044322246.1 56 137 12 213 266 Q9NR16 8.98e-67 Scavenger receptor cysteine-rich type 1 protein M160 (CD163 antigen-like 1) (CD antigen CD163b) Homo sapiens (Human) NA GO:0005044; GO:0005576; GO:0009897 23018 XM_044322246.1 56 137 12 213 266 Q9NR16 2.15e-55 Scavenger receptor cysteine-rich type 1 protein M160 (CD163 antigen-like 1) (CD antigen CD163b) Homo sapiens (Human) NA GO:0005044; GO:0005576; GO:0009897 23019 XM_044322246.1 56 137 12 213 266 Q9NR16 4.41e-49 Scavenger receptor cysteine-rich type 1 protein M160 (CD163 antigen-like 1) (CD antigen CD163b) Homo sapiens (Human) NA GO:0005044; GO:0005576; GO:0009897 23020 XM_044322246.1 56 137 12 213 266 Q9NR16 1.63e-34 Scavenger receptor cysteine-rich type 1 protein M160 (CD163 antigen-like 1) (CD antigen CD163b) Homo sapiens (Human) NA GO:0005044; GO:0005576; GO:0009897 23021 XM_044322246.1 56 137 12 213 266 Q9NR16 1.89e-27 Scavenger receptor cysteine-rich type 1 protein M160 (CD163 antigen-like 1) (CD antigen CD163b) Homo sapiens (Human) NA GO:0005044; GO:0005576; GO:0009897 23022 XM_044307710.1 65 22 3 82 58 NA NA NA NA NA NA 23023 XM_029327001.1 0 0 0 43 0 NA NA NA NA NA NA 23024 XM_044320106.1 0 0 3 14 3 NA NA NA NA NA NA 23025 XM_044319051.1 0 123 0 0 68 NA NA NA NA NA NA 23026 XM_044322672.1 0 8 0 0 0 NA NA NA NA NA NA 23027 XM_029351071.2 926 3091 767 788 1195 NA NA NA NA NA NA 23028 XM_044318354.1 87 28 48 168 177 NA NA NA NA NA NA 23029 XM_029344982.2 306 0 0 0 131 Q8NF64 6.04e-140 Zinc finger MIZ domain-containing protein 2 (PIAS-like protein Zimp7) Homo sapiens (Human) positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0005634; GO:0005654; GO:0005739; GO:0006357; GO:0008270; GO:0030374; GO:0043596; GO:0045944 23030 XM_044321652.1 162 199 88 114 35 Q1LZC5 3.59e-39 Ankyrin repeat domain-containing protein 54 Bos taurus (Bovine) nucleocytoplasmic transport [GO:0006913]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of intracellular signal transduction [GO:1902531]; regulation of protein kinase activity [GO:0045859] GO:0005634; GO:0005737; GO:0006913; GO:0019887; GO:0030496; GO:0044877; GO:0045648; GO:0045859; GO:1902531 23031 XM_044318745.1 440 908 778 642 1300 P52826 0 Carnitine O-acetyltransferase (Carnitine acetylase) (EC 2.3.1.137) (EC 2.3.1.7) (Carnitine acetyltransferase) (CAT) (CrAT) Columba livia (Rock dove) carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; medium-chain fatty acid metabolic process [GO:0051791]; short-chain fatty acid metabolic process [GO:0046459] GO:0003997; GO:0004092; GO:0005743; GO:0005777; GO:0005783; GO:0008458; GO:0019254; GO:0033540; GO:0046459; GO:0051791 23032 XM_044322428.1 45 162 9 50 126 Q5DU56 1.82e-32 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 23033 XM_044322428.1 45 162 9 50 126 Q5DU56 2.99e-29 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 23034 XM_044322428.1 45 162 9 50 126 Q5DU56 1.28e-28 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 23035 XM_044322428.1 45 162 9 50 126 Q5DU56 4.79e-21 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 23036 XM_029324101.2 46 37 12 28 30 NA NA NA NA NA NA 23037 XM_029331214.2 149 114 92 168 111 Q9QX47 9.91e-66 Protein SON (Negative regulatory element-binding protein) (NRE-binding protein) Mus musculus (Mouse) microtubule cytoskeleton organization [GO:0000226]; mitotic cytokinesis [GO:0000281]; mRNA processing [GO:0006397]; negative regulation of apoptotic process [GO:0043066]; regulation of cell cycle [GO:0051726]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380] GO:0000226; GO:0000281; GO:0003677; GO:0003723; GO:0006397; GO:0008380; GO:0016607; GO:0043066; GO:0043484; GO:0048024; GO:0050733; GO:0051726 23038 XR_006397046.1 0 0 0 0 38 NA NA NA NA NA NA 23039 XR_006397840.1 328 148 98 190 193 NA NA NA NA NA NA 23040 XM_029344327.2 0 0 66 47 0 Q91WC7 1.32e-85 NIPA-like protein 2 Mus musculus (Mouse) magnesium ion transport [GO:0015693] GO:0015095; GO:0015693; GO:0016020 23041 XR_006397738.1 2526 829 2170 3025 2391 NA NA NA NA NA NA 23042 XM_044307616.1 1509 895 257 634 470 NA NA NA NA NA NA 23043 XM_029338962.2 70 50 20 92 29 NA NA NA NA NA NA 23044 XM_029332619.2 43 38 108 93 81 G3M4F8 1.73e-26 Octopamine receptor beta-2R (CsOA2B2) Chilo suppressalis (Asiatic rice borer moth) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cellular response to amine stimulus [GO:0071418]; octopamine signaling pathway [GO:0071927]; tyramine signaling pathway [GO:0071928] GO:0004989; GO:0005886; GO:0007189; GO:0008226; GO:0016020; GO:0071418; GO:0071927; GO:0071928 23045 XR_006397758.1 33 28 0 0 0 NA NA NA NA NA NA 23046 XM_029333579.2 34 12 0 19 28 Q9R050 1.38e-56 Single-stranded DNA-binding protein 3 (Sequence-specific single-stranded-DNA-binding protein) Rattus norvegicus (Rat) DNA-templated transcription elongation [GO:0006354]; head development [GO:0060322]; head morphogenesis [GO:0060323]; hematopoietic progenitor cell differentiation [GO:0002244]; mesendoderm development [GO:0048382]; midbrain-hindbrain boundary initiation [GO:0021547]; positive regulation of anterior head development [GO:2000744]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; prechordal plate formation [GO:0021501]; protein-containing complex assembly [GO:0065003] GO:0002244; GO:0003697; GO:0003713; GO:0005634; GO:0005667; GO:0006354; GO:0008284; GO:0021501; GO:0021547; GO:0032991; GO:0045893; GO:0045944; GO:0048382; GO:0060322; GO:0060323; GO:0065003; GO:2000744 23047 XM_029340007.2 780 730 687 650 885 Q5ZLX5 1.2e-52 Zinc finger Ran-binding domain-containing protein 2 Gallus gallus (Chicken) RNA processing [GO:0006396] GO:0001530; GO:0003723; GO:0005634; GO:0006396; GO:0046872 23048 XM_044321645.1 54 54 58 17 150 NA NA NA NA NA NA 23049 XM_044307131.1 12 0 15 133 10 Q9U6Y6 4.67e-101 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 23050 XM_044324186.1 2860 3095 833 2263 1298 Q96DX5 2.41e-34 Ankyrin repeat and SOCS box protein 9 (ASB-9) Homo sapiens (Human) intracellular signal transduction [GO:0035556]; positive regulation of protein catabolic process [GO:0045732]; protein ubiquitination [GO:0016567] GO:0005739; GO:0005829; GO:0016567; GO:0035556; GO:0045732 23051 XM_044310455.1 336 139 418 402 1740 NA NA NA NA NA NA 23052 XR_006395901.1 15 33 53 82 27 NA NA NA NA NA NA 23053 XM_044328243.1 500 572 291 1244 1316 NA NA NA NA NA NA 23054 XM_029355868.2 273 240 68 164 158 NA NA NA NA NA NA 23055 XM_044323723.1 0 4 0 11 10 NA NA NA NA NA NA 23056 XM_029356356.2 1576 861 810 1027 1235 P05625 3.35e-179 RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (C-MIL) (C-RAF) (MIL proto-oncogene serine/threonine-protein kinase) (RAF-1) Gallus gallus (Chicken) MAPK cascade [GO:0000165]; protein phosphorylation [GO:0006468] GO:0000165; GO:0004674; GO:0004709; GO:0005524; GO:0005737; GO:0005739; GO:0005829; GO:0005886; GO:0006468; GO:0046872; GO:0106310 23057 XM_029329915.2 210 185 118 58 239 B8VIU6 7.94e-137 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 23058 XM_044326487.1 10 13 35 4 85 NA NA NA NA NA NA 23059 XM_044319583.1 165 114 56 132 129 Q9CYL5 8.99e-25 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Mus musculus (Mouse) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070374 23060 XM_044328151.1 111 90 84 0 76 P11362 1.23e-63 Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331) Homo sapiens (Human) cell migration [GO:0016477]; chordate embryonic development [GO:0043009]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; MAPK cascade [GO:0000165]; neuron migration [GO:0001764]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell differentiation [GO:0045595]; regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001239]; skeletal system development [GO:0001501]; skeletal system morphogenesis [GO:0048705]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0000165; GO:0001501; GO:0001764; GO:0001837; GO:0004713; GO:0004714; GO:0005007; GO:0005524; GO:0005576; GO:0005634; GO:0005829; GO:0005886; GO:0006468; GO:0007169; GO:0008201; GO:0008284; GO:0008543; GO:0010518; GO:0010863; GO:0014068; GO:0016020; GO:0016477; GO:0017134; GO:0018108; GO:0031410; GO:0033674; GO:0042802; GO:0042803; GO:0043009; GO:0043235; GO:0043406; GO:0043410; GO:0043536; GO:0045595; GO:0045597; GO:0045666; GO:0046777; GO:0048015; GO:0048705; GO:0051897; GO:0090722; GO:1905564; GO:2000546; GO:2001239 23061 XM_029357991.2 0 2 9 0 8 Q6ZQY2 8.66e-28 Leucine-rich repeat-containing protein 74B Homo sapiens (Human) NA NA 23062 XM_044312361.1 1359 1545 761 1068 621 Q27245 3.01e-133 Putative aminopeptidase W07G4.4 (EC 3.4.11.-) Caenorhabditis elegans proteolysis [GO:0006508] GO:0005737; GO:0006508; GO:0008233; GO:0030145; GO:0070006 23063 XM_029323562.2 1780 962 957 2043 2083 O35161 0 Cadherin EGF LAG seven-pass G-type receptor 1 Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; apical protein localization [GO:0045176]; cell-cell adhesion [GO:0098609]; establishment of body hair planar orientation [GO:0048105]; establishment of planar polarity [GO:0001736]; establishment of planar polarity of embryonic epithelium [GO:0042249]; hair follicle development [GO:0001942]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear morphogenesis [GO:0042472]; lateral sprouting involved in lung morphogenesis [GO:0060490]; locomotory behavior [GO:0007626]; motor neuron migration [GO:0097475]; neural tube closure [GO:0001843]; orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060488]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060489]; protein localization involved in establishment of planar polarity [GO:0090251]; regulation of actin cytoskeleton organization [GO:0032956]; Rho protein signal transduction [GO:0007266]; wound healing [GO:0042060] GO:0001736; GO:0001843; GO:0001942; GO:0004930; GO:0005509; GO:0005654; GO:0005886; GO:0007156; GO:0007266; GO:0007626; GO:0009952; GO:0016020; GO:0032956; GO:0042060; GO:0042249; GO:0042472; GO:0045176; GO:0048105; GO:0060488; GO:0060489; GO:0060490; GO:0090179; GO:0090251; GO:0097475; GO:0098609 23064 XM_029347021.2 15 8 12 0 17 NA NA NA NA NA NA 23065 XM_044312062.1 0 0 11 0 7 NA NA NA NA NA NA 23066 XR_006397883.1 36 8 27 25 108 NA NA NA NA NA NA 23067 XM_044322082.1 75 313 0 371 322 B1AJZ9 4.06e-33 Forkhead-associated domain-containing protein 1 (FHA domain-containing protein 1) Homo sapiens (Human) NA NA 23068 XM_044322082.1 75 313 0 371 322 B1AJZ9 9.97e-29 Forkhead-associated domain-containing protein 1 (FHA domain-containing protein 1) Homo sapiens (Human) NA NA 23069 XM_044311296.1 52 0 65 15 111 Q91W78 4.81e-22 U6 snRNA phosphodiesterase 1 (3'-5' RNA exonuclease USB1) (EC 4.6.1.-) Mus musculus (Mouse) RNA splicing [GO:0008380]; snRNA 3'-end processing [GO:0034472]; U6 snRNA 3'-end processing [GO:0034477] GO:0000175; GO:0005634; GO:0005654; GO:0008380; GO:0016829; GO:0034472; GO:0034477; GO:0045171; GO:1990838 23070 XM_044320270.1 38 1 45 1 149 P0CT39 7.82e-79 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 23071 XM_044319884.1 0 5 52 15 0 NA NA NA NA NA NA 23072 XR_003823244.2 198 644 359 410 261 NA NA NA NA NA NA 23073 XM_029357790.2 61 0 10 94 185 Q9EQD2 8.1e-46 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 23074 XM_029330034.2 742 569 455 940 1004 Q96MT7 0 Cilia- and flagella-associated protein 44 (WD repeat-containing protein 52) Homo sapiens (Human) cilium assembly [GO:0060271]; cilium-dependent cell motility [GO:0060285]; microtubule cytoskeleton organization [GO:0000226]; sperm axoneme assembly [GO:0007288] GO:0000226; GO:0005737; GO:0005856; GO:0007288; GO:0008233; GO:0031514; GO:0060271; GO:0060285 23075 XM_029330034.2 742 569 455 940 1004 Q96MT7 1.31e-123 Cilia- and flagella-associated protein 44 (WD repeat-containing protein 52) Homo sapiens (Human) cilium assembly [GO:0060271]; cilium-dependent cell motility [GO:0060285]; microtubule cytoskeleton organization [GO:0000226]; sperm axoneme assembly [GO:0007288] GO:0000226; GO:0005737; GO:0005856; GO:0007288; GO:0008233; GO:0031514; GO:0060271; GO:0060285 23076 XM_029330034.2 742 569 455 940 1004 Q96MT7 2.83e-55 Cilia- and flagella-associated protein 44 (WD repeat-containing protein 52) Homo sapiens (Human) cilium assembly [GO:0060271]; cilium-dependent cell motility [GO:0060285]; microtubule cytoskeleton organization [GO:0000226]; sperm axoneme assembly [GO:0007288] GO:0000226; GO:0005737; GO:0005856; GO:0007288; GO:0008233; GO:0031514; GO:0060271; GO:0060285 23077 XR_006396944.1 0 6 0 2 0 Q6DIV6 2.01e-29 Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Solute carrier family 32 member 1) (Vesicular GABA transporter) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) beta-alanine transport [GO:0001762]; gamma-aminobutyric acid import [GO:0051939]; gamma-aminobutyric acid transport [GO:0015812]; glycine transport [GO:0015816]; neurotransmitter transport [GO:0006836] GO:0001762; GO:0006836; GO:0008021; GO:0015185; GO:0015187; GO:0015812; GO:0015816; GO:0030659; GO:0042995; GO:0051939; GO:0098793; GO:0140799; GO:0140800 23078 XM_029354255.2 0 10 0 0 1 NA NA NA NA NA NA 23079 XM_029330832.2 865 561 606 563 862 NA NA NA NA NA NA 23080 XR_003824645.2 725 334 118 288 235 NA NA NA NA NA NA 23081 XM_029331052.2 9 15 38 22 66 NA NA NA NA NA NA 23082 XM_044313777.1 13 31 23 9 50 Q9CR48 1.95e-34 DNA damage-regulated autophagy modulator protein 2 (Transmembrane protein 77) Mus musculus (Mouse) apoptotic process [GO:0006915]; autophagy [GO:0006914]; photoreceptor cell maintenance [GO:0045494]; regulation of autophagy [GO:0010506]; visual perception [GO:0007601] GO:0001917; GO:0005737; GO:0005764; GO:0005765; GO:0005794; GO:0006914; GO:0006915; GO:0007601; GO:0010506; GO:0016324; GO:0043231; GO:0045494 23083 XM_029348959.2 522 485 501 375 440 Q58DN4 1.1e-121 Protein phosphatase methylesterase 1 (PME-1) (EC 3.1.1.89) Bos taurus (Bovine) protein demethylation [GO:0006482]; protein phosphorylation [GO:0006468] GO:0006468; GO:0006482; GO:0051721; GO:0051722; GO:0051723; GO:0106222 23084 XR_003825540.2 291 287 298 405 432 NA NA NA NA NA NA 23085 XM_044314747.1 226 83 113 82 91 NA NA NA NA NA NA 23086 XM_044329301.1 213 42 202 164 387 P08575 1.13e-35 Receptor-type tyrosine-protein phosphatase C (EC 3.1.3.48) (Leukocyte common antigen) (L-CA) (T200) (CD antigen CD45) Homo sapiens (Human) alpha-beta T cell proliferation [GO:0046633]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; B cell receptor signaling pathway [GO:0050853]; bone marrow development [GO:0048539]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell cycle phase transition [GO:0044770]; cell surface receptor signaling pathway [GO:0007166]; cellular response to extracellular stimulus [GO:0031668]; defense response to virus [GO:0051607]; dephosphorylation [GO:0016311]; DN2 thymocyte differentiation [GO:1904155]; extrinsic apoptotic signaling pathway [GO:0097191]; gamma-delta T cell differentiation [GO:0042492]; hematopoietic progenitor cell differentiation [GO:0002244]; heterotypic cell-cell adhesion [GO:0034113]; leukocyte cell-cell adhesion [GO:0007159]; MAPK cascade [GO:0000165]; natural killer cell differentiation [GO:0001779]; negative regulation of cell adhesion involved in substrate-bound cell migration [GO:0006933]; negative regulation of cytokine-mediated signaling pathway [GO:0001960]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of microglial cell activation [GO:1903979]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein tyrosine kinase activity [GO:0061099]; negative regulation of T cell mediated cytotoxicity [GO:0001915]; negative thymic T cell selection [GO:0045060]; peptidyl-tyrosine phosphorylation [GO:0018108]; plasma membrane raft distribution [GO:0044855]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of antigen receptor-mediated signaling pathway [GO:0050857]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis [GO:1905451]; positive regulation of gamma-delta T cell differentiation [GO:0045588]; positive regulation of hematopoietic stem cell migration [GO:2000473]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein tyrosine phosphatase activity [GO:1903615]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tumor necrosis factor production [GO:0032760]; positive thymic T cell selection [GO:0045059]; protein autophosphorylation [GO:0046777]; protein dephosphorylation [GO:0006470]; regulation of cell cycle [GO:0051726]; regulation of gene expression [GO:0010468]; regulation of interleukin-8 production [GO:0032677]; regulation of phagocytosis [GO:0050764]; regulation of protein tyrosine kinase activity [GO:0061097]; regulation of receptor signaling pathway via JAK-STAT [GO:0046425]; release of sequestered calcium ion into cytosol [GO:0051209]; response to gamma radiation [GO:0010332]; stem cell development [GO:0048864]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852] GO:0000165; GO:0001779; GO:0001915; GO:0001916; GO:0001960; GO:0002244; GO:0002639; GO:0002925; GO:0004725; GO:0005001; GO:0005102; GO:0005886; GO:0005925; GO:0006469; GO:0006470; GO:0006933; GO:0007159; GO:0007166; GO:0008201; GO:0009897; GO:0009898; GO:0009986; GO:0010332; GO:0010468; GO:0016020; GO:0016311; GO:0018108; GO:0019901; GO:0030183; GO:0030217; GO:0030506; GO:0030507; GO:0030667; GO:0030890; GO:0031668; GO:0031953; GO:0032059; GO:0032677; GO:0032703; GO:0032743; GO:0032760; GO:0034113; GO:0035584; GO:0042100; GO:0042102; GO:0042110; GO:0042492; GO:0043395; GO:0043406; GO:0043410; GO:0044770; GO:0044855; GO:0045059; GO:0045060; GO:0045121; GO:0045588; GO:0045860; GO:0046425; GO:0046633; GO:0046641; GO:0046777; GO:0048304; GO:0048539; GO:0048864; GO:0050731; GO:0050764; GO:0050852; GO:0050853; GO:0050857; GO:0051209; GO:0051607; GO:0051726; GO:0061097; GO:0061099; GO:0070062; GO:0070373; GO:0070374; GO:0097191; GO:0098857; GO:1903615; GO:1903979; GO:1904155; GO:1905451; GO:2000473; GO:2000648; GO:2001238 23087 XM_044329301.1 213 42 202 164 387 P08575 1.38e-22 Receptor-type tyrosine-protein phosphatase C (EC 3.1.3.48) (Leukocyte common antigen) (L-CA) (T200) (CD antigen CD45) Homo sapiens (Human) alpha-beta T cell proliferation [GO:0046633]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; B cell receptor signaling pathway [GO:0050853]; bone marrow development [GO:0048539]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell cycle phase transition [GO:0044770]; cell surface receptor signaling pathway [GO:0007166]; cellular response to extracellular stimulus [GO:0031668]; defense response to virus [GO:0051607]; dephosphorylation [GO:0016311]; DN2 thymocyte differentiation [GO:1904155]; extrinsic apoptotic signaling pathway [GO:0097191]; gamma-delta T cell differentiation [GO:0042492]; hematopoietic progenitor cell differentiation [GO:0002244]; heterotypic cell-cell adhesion [GO:0034113]; leukocyte cell-cell adhesion [GO:0007159]; MAPK cascade [GO:0000165]; natural killer cell differentiation [GO:0001779]; negative regulation of cell adhesion involved in substrate-bound cell migration [GO:0006933]; negative regulation of cytokine-mediated signaling pathway [GO:0001960]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of microglial cell activation [GO:1903979]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein tyrosine kinase activity [GO:0061099]; negative regulation of T cell mediated cytotoxicity [GO:0001915]; negative thymic T cell selection [GO:0045060]; peptidyl-tyrosine phosphorylation [GO:0018108]; plasma membrane raft distribution [GO:0044855]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of antigen receptor-mediated signaling pathway [GO:0050857]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis [GO:1905451]; positive regulation of gamma-delta T cell differentiation [GO:0045588]; positive regulation of hematopoietic stem cell migration [GO:2000473]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein tyrosine phosphatase activity [GO:1903615]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tumor necrosis factor production [GO:0032760]; positive thymic T cell selection [GO:0045059]; protein autophosphorylation [GO:0046777]; protein dephosphorylation [GO:0006470]; regulation of cell cycle [GO:0051726]; regulation of gene expression [GO:0010468]; regulation of interleukin-8 production [GO:0032677]; regulation of phagocytosis [GO:0050764]; regulation of protein tyrosine kinase activity [GO:0061097]; regulation of receptor signaling pathway via JAK-STAT [GO:0046425]; release of sequestered calcium ion into cytosol [GO:0051209]; response to gamma radiation [GO:0010332]; stem cell development [GO:0048864]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852] GO:0000165; GO:0001779; GO:0001915; GO:0001916; GO:0001960; GO:0002244; GO:0002639; GO:0002925; GO:0004725; GO:0005001; GO:0005102; GO:0005886; GO:0005925; GO:0006469; GO:0006470; GO:0006933; GO:0007159; GO:0007166; GO:0008201; GO:0009897; GO:0009898; GO:0009986; GO:0010332; GO:0010468; GO:0016020; GO:0016311; GO:0018108; GO:0019901; GO:0030183; GO:0030217; GO:0030506; GO:0030507; GO:0030667; GO:0030890; GO:0031668; GO:0031953; GO:0032059; GO:0032677; GO:0032703; GO:0032743; GO:0032760; GO:0034113; GO:0035584; GO:0042100; GO:0042102; GO:0042110; GO:0042492; GO:0043395; GO:0043406; GO:0043410; GO:0044770; GO:0044855; GO:0045059; GO:0045060; GO:0045121; GO:0045588; GO:0045860; GO:0046425; GO:0046633; GO:0046641; GO:0046777; GO:0048304; GO:0048539; GO:0048864; GO:0050731; GO:0050764; GO:0050852; GO:0050853; GO:0050857; GO:0051209; GO:0051607; GO:0051726; GO:0061097; GO:0061099; GO:0070062; GO:0070373; GO:0070374; GO:0097191; GO:0098857; GO:1903615; GO:1903979; GO:1904155; GO:1905451; GO:2000473; GO:2000648; GO:2001238 23088 XM_029330014.2 661 391 237 667 280 Q9Y2M2 9.25e-74 Protein SSUH2 homolog (Protein ssu-2 homolog) Homo sapiens (Human) odontogenesis [GO:0042476] GO:0005634; GO:0005737; GO:0031072; GO:0042476; GO:0051082 23089 XM_044315281.1 68 0 0 23 0 NA NA NA NA NA NA 23090 XM_044317502.1 0 10 0 0 4 NA NA NA NA NA NA 23091 XM_044328809.1 13 0 7 140 1 NA NA NA NA NA NA 23092 XM_044307527.1 2 0 1 0 14 Q96PN6 6.26e-41 Adenylate cyclase type 10 (EC 4.6.1.1) (AH-related protein) (Adenylate cyclase homolog) (Germ cell soluble adenylyl cyclase) (hsAC) (sAC) (Testicular soluble adenylyl cyclase) Homo sapiens (Human) cAMP biosynthetic process [GO:0006171]; cellular response to inorganic substance [GO:0071241]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; intracellular signal transduction [GO:0035556]; positive regulation of apoptotic process [GO:0043065]; spermatogenesis [GO:0007283] GO:0000287; GO:0003351; GO:0004016; GO:0005524; GO:0005576; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0005856; GO:0005929; GO:0006171; GO:0007283; GO:0016324; GO:0030145; GO:0030425; GO:0030426; GO:0035556; GO:0043025; GO:0043065; GO:0045178; GO:0048471; GO:0051117; GO:0071241; GO:0071890 23093 XM_044307527.1 2 0 1 0 14 Q96PN6 4.92e-26 Adenylate cyclase type 10 (EC 4.6.1.1) (AH-related protein) (Adenylate cyclase homolog) (Germ cell soluble adenylyl cyclase) (hsAC) (sAC) (Testicular soluble adenylyl cyclase) Homo sapiens (Human) cAMP biosynthetic process [GO:0006171]; cellular response to inorganic substance [GO:0071241]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; intracellular signal transduction [GO:0035556]; positive regulation of apoptotic process [GO:0043065]; spermatogenesis [GO:0007283] GO:0000287; GO:0003351; GO:0004016; GO:0005524; GO:0005576; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0005856; GO:0005929; GO:0006171; GO:0007283; GO:0016324; GO:0030145; GO:0030425; GO:0030426; GO:0035556; GO:0043025; GO:0043065; GO:0045178; GO:0048471; GO:0051117; GO:0071241; GO:0071890 23094 XM_044324443.1 11 949 14 799 1356 NA NA NA NA NA NA 23095 XM_029346074.2 496 400 338 676 559 Q93015 2.81e-23 N-alpha-acetyltransferase 80 (HsNAAA80) (EC 2.3.1.-) (N-acetyltransferase 6) (Protein fusion-2) (Protein fus-2) Homo sapiens (Human) actin modification [GO:0030047]; N-terminal peptidyl-aspartic acid acetylation [GO:0017190]; N-terminal peptidyl-glutamic acid acetylation [GO:0018002]; protein acetylation [GO:0006473]; regulation of actin polymerization or depolymerization [GO:0008064] GO:0004596; GO:0005737; GO:0005829; GO:0006473; GO:0008064; GO:0008080; GO:0017190; GO:0018002; GO:0030047; GO:1905502 23096 XM_044325441.1 701 209 300 470 343 A6QLU6 1.25e-24 Adhesion G-protein coupled receptor D1 (G-protein coupled receptor 133) Bos taurus (Bovine) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0005886; GO:0007166; GO:0007186; GO:0007189 23097 XM_044307709.1 47 14 15 140 160 NA NA NA NA NA NA 23098 XR_006397583.1 91 123 51 147 177 NA NA NA NA NA NA 23099 XM_044315016.1 3 8 10 22 2 NA NA NA NA NA NA 23100 XM_029327154.2 591 234 165 229 595 Q9GV16 0 Endoglycoceramidase (EGCase) (EC 3.2.1.123) (Glycosphingolipid-specific enzyme) (GSL-specific enzyme) Cyanea nozakii (Jellyfish) carbohydrate derivative catabolic process [GO:1901136]; cellulose catabolic process [GO:0030245]; lipid catabolic process [GO:0016042] GO:0005576; GO:0016042; GO:0030245; GO:0042151; GO:0047876; GO:1901136 23101 XM_044327683.1 13 4 2 5 12 NA NA NA NA NA NA 23102 XM_044323504.1 207 98 223 132 99 Q6TDP4 9.98e-134 Kelch-like protein 17 (Actinfilin) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; protein ubiquitination [GO:0016567]; regulation protein catabolic process at postsynapse [GO:0140252] GO:0005615; GO:0007420; GO:0014069; GO:0015629; GO:0016567; GO:0030036; GO:0031208; GO:0032839; GO:0043025; GO:0051015; GO:0060090; GO:0098978; GO:0140252 23103 XM_044323504.1 207 98 223 132 99 Q6TDP4 7.5e-37 Kelch-like protein 17 (Actinfilin) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; protein ubiquitination [GO:0016567]; regulation protein catabolic process at postsynapse [GO:0140252] GO:0005615; GO:0007420; GO:0014069; GO:0015629; GO:0016567; GO:0030036; GO:0031208; GO:0032839; GO:0043025; GO:0051015; GO:0060090; GO:0098978; GO:0140252 23104 XM_029329330.2 1000 806 390 666 403 Q16960 0 Dynein intermediate chain 3, ciliary Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina) NA GO:0005737; GO:0005874; GO:0005929; GO:0030286 23105 XM_029344026.2 531 503 422 850 1166 Q9BXB1 6.3e-127 Leucine-rich repeat-containing G-protein coupled receptor 4 (G-protein coupled receptor 48) Homo sapiens (Human) bone mineralization [GO:0030282]; bone remodeling [GO:0046849]; canonical Wnt signaling pathway involved in metanephric kidney development [GO:0061290]; cell differentiation involved in metanephros development [GO:0072202]; circadian regulation of gene expression [GO:0032922]; digestive tract development [GO:0048565]; epithelial cell proliferation involved in renal tubule morphogenesis [GO:2001013]; hair follicle development [GO:0001942]; innate immune response [GO:0045087]; intestinal stem cell homeostasis [GO:0036335]; male genitalia development [GO:0030539]; metanephric glomerulus development [GO:0072224]; metanephric nephron tubule morphogenesis [GO:0072282]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of cytokine production [GO:0001818]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; osteoblast differentiation [GO:0001649]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of DNA-templated transcription [GO:0045893]; spermatogenesis [GO:0007283] GO:0001649; GO:0001818; GO:0001942; GO:0004888; GO:0004930; GO:0005886; GO:0007283; GO:0016500; GO:0030282; GO:0030539; GO:0032922; GO:0034122; GO:0036335; GO:0045087; GO:0045892; GO:0045893; GO:0046849; GO:0048565; GO:0061290; GO:0072202; GO:0072224; GO:0072282; GO:0090190; GO:0090263; GO:0120163; GO:2001013 23106 XM_029337557.2 11 2 0 11 2 NA NA NA NA NA NA 23107 XM_029342072.2 12141 3561 1592 8671 636 NA NA NA NA NA NA 23108 XM_029334122.2 43 42 34 70 84 Q09225 1.85e-70 Nose resistant to fluoxetine protein 6 (Protein nrf-6) Caenorhabditis elegans lipid transport [GO:0006869] GO:0006869; GO:0008289; GO:0016020; GO:0016747 23109 XM_044312747.1 100 100 30 63 73 Q92900 2.04e-77 Regulator of nonsense transcripts 1 (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up-frameshift suppressor 1 homolog) (hUpf1) Homo sapiens (Human) 3'-UTR-mediated mRNA destabilization [GO:0061158]; cell cycle phase transition [GO:0044770]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; DNA duplex unwinding [GO:0032508]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; histone mRNA catabolic process [GO:0071044]; mRNA export from nucleus [GO:0006406]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay [GO:0000294]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of mRNA catabolic process [GO:0061014]; regulation of telomere maintenance [GO:0032204]; regulation of translational termination [GO:0006449]; telomere maintenance via semi-conservative replication [GO:0032201] GO:0000184; GO:0000294; GO:0000781; GO:0000785; GO:0000932; GO:0000956; GO:0003682; GO:0003723; GO:0003724; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006260; GO:0006281; GO:0006406; GO:0006449; GO:0008270; GO:0016887; GO:0032201; GO:0032204; GO:0032508; GO:0035145; GO:0036121; GO:0042162; GO:0044530; GO:0044770; GO:0044877; GO:0048471; GO:0061014; GO:0061158; GO:0071044; GO:0071222; GO:0071347 23110 XM_029338555.2 266 189 96 312 248 Q5XK92 0 Protein CIP2A homolog Xenopus laevis (African clawed frog) NA GO:0005737; GO:0016020 23111 XM_029324169.2 3480 987 950 662 188 P80147 0 4-aminobutyrate aminotransferase, mitochondrial (EC 2.6.1.19) ((S)-3-amino-2-methylpropionate transaminase) (EC 2.6.1.22) (GABA aminotransferase) (GABA-AT) (Gamma-amino-N-butyrate transaminase) (GABA transaminase) (GABA-T) (L-AIBAT) Sus scrofa (Pig) behavioral response to cocaine [GO:0048148]; gamma-aminobutyric acid catabolic process [GO:0009450]; neurotransmitter catabolic process [GO:0042135] GO:0005739; GO:0005759; GO:0005829; GO:0009450; GO:0030170; GO:0032144; GO:0032145; GO:0034386; GO:0042135; GO:0042802; GO:0042803; GO:0046872; GO:0047298; GO:0048148; GO:0051537 23112 XM_029339329.2 31 0 0 0 39 NA NA NA NA NA NA 23113 XM_044317393.1 10774 9301 3958 7008 15011 NA NA NA NA NA NA 23114 XM_029334862.2 744 455 472 661 695 Q17QK3 7.44e-177 Carboxypeptidase Q (EC 3.4.17.-) (Plasma glutamate carboxypeptidase) Bos taurus (Bovine) peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]; thyroid hormone generation [GO:0006590]; tissue regeneration [GO:0042246] GO:0004180; GO:0005615; GO:0005737; GO:0005764; GO:0005783; GO:0005794; GO:0006508; GO:0006590; GO:0042246; GO:0042803; GO:0043171; GO:0046872; GO:0070573 23115 XM_044326919.1 0 1 25 2 8 NA NA NA NA NA NA 23116 XR_006394313.1 186 84 143 102 130 NA NA NA NA NA NA 23117 XM_044318145.1 89 0 6 0 21 NA NA NA NA NA NA 23118 XM_029349173.2 418 226 750 946 357 NA NA NA NA NA NA 23119 XR_006396869.1 639 200 477 297 1383 NA NA NA NA NA NA 23120 XM_029340906.2 2 4 18 6 12 NA NA NA NA NA NA 23121 XR_006396334.1 0 0 8 6 31 NA NA NA NA NA NA 23122 XM_044313520.1 37 16 207 69 252 A0A0C2SRU0 8.65e-81 Decarboxylase iboD (EC 4.1.1.-) (Ibotenic acid biosynthesis cluster protein D) Amanita muscaria (strain Koide BX008) phospholipid biosynthetic process [GO:0008654] GO:0004609; GO:0008654 23123 XM_029327666.2 234 59 119 15 126 Q99315 2.21e-86 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 23124 XM_029335864.2 3609 2126 2578 3067 3435 Q5R1W5 1.49e-40 Serine/arginine-rich splicing factor 2 (Splicing component, 35 kDa) (Splicing factor SC35) (SC-35) (Splicing factor, arginine/serine-rich 2) Pan troglodytes (Chimpanzee) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0003723; GO:0006397; GO:0008380; GO:0016607 23125 XM_044329285.1 0 22 2 27 90 Q8BJ37 3.86e-145 Tyrosyl-DNA phosphodiesterase 1 (Tyr-DNA phosphodiesterase 1) (EC 3.1.4.-) (Protein expressed in male leptotene and zygotene spermatocytes 501) (MLZ-501) Mus musculus (Mouse) DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; single strand break repair [GO:0000012] GO:0000012; GO:0003690; GO:0003697; GO:0004527; GO:0005634; GO:0005654; GO:0005886; GO:0006281; GO:0006302; GO:0017005; GO:0043231 23126 XM_029355631.2 139 34 104 73 19 NA NA NA NA NA NA 23127 XM_029349250.2 238 192 117 282 242 Q9D273 1.97e-69 Corrinoid adenosyltransferase MMAB (EC 2.5.1.-) (ATP:co(I)rrinoid adenosyltransferase MMAB) (Methylmalonic aciduria type B homolog) Mus musculus (Mouse) cobalamin metabolic process [GO:0009235] GO:0005524; GO:0005739; GO:0008817; GO:0009235; GO:0016765; GO:0031419 23128 XM_044323634.1 110 11 83 23 277 NA NA NA NA NA NA 23129 XM_044326543.1 147 43 111 98 181 NA NA NA NA NA NA 23130 XM_029347540.2 184 148 88 119 83 NA NA NA NA NA NA 23131 XR_006395263.1 17 52 3 0 12 NA NA NA NA NA NA 23132 XR_006392169.1 0 14 1 0 5 NA NA NA NA NA NA 23133 XM_029344030.2 9932 10621 6374 10252 6675 Q8MPM1 7.75e-112 Gelsolin-like protein 2 (Actin-modulator) (EWAM-P2) Lumbricus terrestris (Common earthworm) actin filament capping [GO:0051693] GO:0005737; GO:0005856; GO:0051015; GO:0051693 23134 XM_044321326.1 41 20 22 10 53 P46023 1.78e-114 G-protein coupled receptor GRL101 Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004930; GO:0005886 23135 XM_044328689.1 17 0 39 0 0 P16065 5.27e-154 Speract receptor (EC 4.6.1.2) (Guanylate cyclase) Strongylocentrotus purpuratus (Purple sea urchin) cGMP biosynthetic process [GO:0006182]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]; receptor guanylyl cyclase signaling pathway [GO:0007168]; signal transduction [GO:0007165] GO:0001653; GO:0004383; GO:0004672; GO:0005524; GO:0005525; GO:0005886; GO:0006182; GO:0006468; GO:0007165; GO:0007168; GO:0035556 23136 XM_044316860.1 777 307 367 188 139 NA NA NA NA NA NA 23137 XM_044322120.1 57 98 48 48 122 NA NA NA NA NA NA 23138 XM_029342573.2 6707 5135 723 1423 1321 NA NA NA NA NA NA 23139 XM_029340485.2 909 659 315 438 186 NA NA NA NA NA NA 23140 XM_044317476.1 92 367 142 654 162 Q5TC82 3.22e-173 Roquin-1 (Roquin) (EC 2.3.2.27) (RING finger and C3H zinc finger protein 1) (RING finger and CCCH-type zinc finger domain-containing protein 1) (RING finger protein 198) Homo sapiens (Human) 3'-UTR-mediated mRNA destabilization [GO:0061158]; B cell homeostasis [GO:0001782]; cellular response to interleukin-1 [GO:0071347]; lymph node development [GO:0048535]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of germinal center formation [GO:0002635]; negative regulation of T-helper 17 cell differentiation [GO:2000320]; negative regulation of T-helper cell differentiation [GO:0045623]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; P-body assembly [GO:0033962]; positive regulation of mRNA catabolic process [GO:0061014]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; post-transcriptional regulation of gene expression [GO:0010608]; protein polyubiquitination [GO:0000209]; regulation of germinal center formation [GO:0002634]; regulation of miRNA metabolic process [GO:2000628]; regulation of mRNA stability [GO:0043488]; regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900151]; regulation of T cell receptor signaling pathway [GO:0050856]; spleen development [GO:0048536]; T cell homeostasis [GO:0043029]; T cell proliferation [GO:0042098]; T cell receptor signaling pathway [GO:0050852]; T follicular helper cell differentiation [GO:0061470]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000209; GO:0000288; GO:0000932; GO:0000956; GO:0001782; GO:0002634; GO:0002635; GO:0003723; GO:0003725; GO:0003729; GO:0003730; GO:0004842; GO:0006511; GO:0008270; GO:0010494; GO:0010608; GO:0030889; GO:0033962; GO:0035198; GO:0035613; GO:0042098; GO:0043029; GO:0043488; GO:0045623; GO:0046007; GO:0048535; GO:0048536; GO:0050852; GO:0050856; GO:0061014; GO:0061158; GO:0061470; GO:0061630; GO:0071347; GO:1900151; GO:1901224; GO:1905762; GO:2000320; GO:2000628 23141 XM_044321357.1 26 33 27 20 67 Q96AY4 7.53e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23142 XM_044317822.1 824 351 399 6 1 Q7KTX8 8.74e-66 Mediator of RNA polymerase II transcription subunit 13 (Mediator complex subunit 13) (Mediator complex subunit Skuld) (Protein blind spot) (Protein poils aux pattes) (dTRAP240) Drosophila melanogaster (Fruit fly) cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; compound eye development [GO:0048749]; imaginal disc-derived leg segmentation [GO:0036011]; larval somatic muscle development [GO:0007526]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; regulation of transcription by RNA polymerase II [GO:0006357]; sex comb development [GO:0045498]; transcription initiation at RNA polymerase II promoter [GO:0006367]; wing disc dorsal/ventral pattern formation [GO:0048190] GO:0003712; GO:0005634; GO:0005654; GO:0006357; GO:0006367; GO:0007526; GO:0016592; GO:0022416; GO:0036011; GO:0045165; GO:0045498; GO:0048190; GO:0048749; GO:0070847; GO:0090263 23143 XM_044317822.1 824 351 399 6 1 Q7KTX8 3.2e-45 Mediator of RNA polymerase II transcription subunit 13 (Mediator complex subunit 13) (Mediator complex subunit Skuld) (Protein blind spot) (Protein poils aux pattes) (dTRAP240) Drosophila melanogaster (Fruit fly) cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; compound eye development [GO:0048749]; imaginal disc-derived leg segmentation [GO:0036011]; larval somatic muscle development [GO:0007526]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; regulation of transcription by RNA polymerase II [GO:0006357]; sex comb development [GO:0045498]; transcription initiation at RNA polymerase II promoter [GO:0006367]; wing disc dorsal/ventral pattern formation [GO:0048190] GO:0003712; GO:0005634; GO:0005654; GO:0006357; GO:0006367; GO:0007526; GO:0016592; GO:0022416; GO:0036011; GO:0045165; GO:0045498; GO:0048190; GO:0048749; GO:0070847; GO:0090263 23144 XM_029329485.2 239 112 169 118 726 Q9BE72 5.5e-98 Solute carrier family 2, facilitated glucose transporter member 12 (Glucose transporter type 12) (GLUT-12) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) carbohydrate transport [GO:0008643] GO:0005886; GO:0008643; GO:0012505; GO:0022857; GO:0048471 23145 XM_044306848.1 105 195 120 334 600 Q8CCP0 0 Ribosome quality control complex subunit NEMF (Nuclear export mediator factor) (Serologically defined colon cancer antigen 1 homolog) Mus musculus (Mouse) CAT tailing [GO:0140708]; nuclear export [GO:0051168]; protein-containing complex assembly [GO:0065003]; rescue of stalled ribosome [GO:0072344]; ribosome-associated ubiquitin-dependent protein catabolic process [GO:1990116] GO:0000049; GO:0005634; GO:0005829; GO:0043023; GO:0051168; GO:0065003; GO:0072344; GO:0140708; GO:1990112; GO:1990116 23146 XM_044306848.1 105 195 120 334 600 Q8CCP0 4.76e-33 Ribosome quality control complex subunit NEMF (Nuclear export mediator factor) (Serologically defined colon cancer antigen 1 homolog) Mus musculus (Mouse) CAT tailing [GO:0140708]; nuclear export [GO:0051168]; protein-containing complex assembly [GO:0065003]; rescue of stalled ribosome [GO:0072344]; ribosome-associated ubiquitin-dependent protein catabolic process [GO:1990116] GO:0000049; GO:0005634; GO:0005829; GO:0043023; GO:0051168; GO:0065003; GO:0072344; GO:0140708; GO:1990112; GO:1990116 23147 XM_044310771.1 7 0 13 3 11 NA NA NA NA NA NA 23148 XM_044325200.1 0 767 0 0 0 NA NA NA NA NA NA 23149 XM_029354057.2 35 46 49 80 111 O02350 8.77e-80 Zinc carboxypeptidase A 1 (EC 3.4.17.-) (AgCP) Anopheles gambiae (African malaria mosquito) digestion [GO:0007586]; proteolysis [GO:0006508] GO:0004181; GO:0005615; GO:0006508; GO:0007586; GO:0008270 23150 XR_006391901.1 75 78 58 253 362 NA NA NA NA NA NA 23151 XM_029348956.2 286 157 101 331 234 Q96DB2 4.63e-109 Histone deacetylase 11 (HD11) (EC 3.5.1.98) Homo sapiens (Human) chromatin organization [GO:0006325]; histone deacetylation [GO:0016575]; oligodendrocyte development [GO:0014003] GO:0000118; GO:0004407; GO:0005634; GO:0005886; GO:0006325; GO:0014003; GO:0016575; GO:0140297 23152 XM_029338032.2 98 89 278 634 674 NA NA NA NA NA NA 23153 XM_029324646.2 898 731 514 658 452 NA NA NA NA NA NA 23154 XM_029337662.2 0 0 36 31 39 O88871 2.43e-117 Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51) Rattus norvegicus (Rat) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; gamma-aminobutyric acid signaling pathway [GO:0007214]; neuron-glial cell signaling [GO:0150099]; synaptic transmission, GABAergic [GO:0051932] GO:0004888; GO:0004965; GO:0005737; GO:0005886; GO:0007193; GO:0007214; GO:0016020; GO:0030425; GO:0038039; GO:0042734; GO:0043005; GO:0043204; GO:0045211; GO:0046982; GO:0051932; GO:0098978; GO:0098982; GO:0150099; GO:1902710; GO:1902712 23155 XM_044306982.1 253 120 90 144 266 Q8IW35 3.53e-41 Centrosomal protein of 97 kDa (Cep97) (Leucine-rich repeat and IQ domain-containing protein 2) Homo sapiens (Human) cell projection organization [GO:0030030]; negative regulation of cilium assembly [GO:1902018]; regulation of mitotic spindle assembly [GO:1901673] GO:0005516; GO:0005813; GO:0005814; GO:0005829; GO:0030030; GO:0032991; GO:1901673; GO:1902018 23156 XR_006393287.1 37 64 16 11 17 NA NA NA NA NA NA 23157 XM_029334022.2 436 247 165 502 298 Q7SX99 0 Fumarate hydratase, mitochondrial (Fumarase) (EC 4.2.1.2) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; fumarate metabolic process [GO:0006106]; malate metabolic process [GO:0006108]; negative regulation of histone H3-K36 methylation [GO:0000415]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of arginine metabolic process [GO:0000821]; tricarboxylic acid cycle [GO:0006099]; urea cycle [GO:0000050] GO:0000050; GO:0000415; GO:0000821; GO:0004333; GO:0005634; GO:0005694; GO:0005739; GO:0005829; GO:0006099; GO:0006106; GO:0006108; GO:0006281; GO:0006974; GO:0045239; GO:2001034 23158 XM_044323328.1 2413 1580 1437 2106 1655 A0A1D5PUP4 0 Reversion-inducing cysteine-rich protein with Kazal motifs Gallus gallus (Chicken) blood vessel maturation [GO:0001955]; extracellular matrix organization [GO:0030198]; negative regulation of metalloendopeptidase activity [GO:1904684]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; regulation of angiogenesis [GO:0045765]; regulation of establishment of blood-brain barrier [GO:0090210]; sprouting angiogenesis [GO:0002040] GO:0001955; GO:0002040; GO:0004866; GO:0004867; GO:0005615; GO:0005886; GO:0008191; GO:0030198; GO:0045765; GO:0090210; GO:0090263; GO:1904684; GO:1904928; GO:1990909 23159 XM_044307825.1 4 9 8 26 12 NA NA NA NA NA NA 23160 XR_006395775.1 6 9 0 0 0 NA NA NA NA NA NA 23161 XM_029334224.2 1292 2054 1163 2207 2560 A8MY62 1.3e-56 Putative beta-lactamase-like 1 Homo sapiens (Human) NA NA 23162 XR_006392294.1 0 0 0 25 0 NA NA NA NA NA NA 23163 XM_029330595.2 245 172 138 156 119 Q80RC7 1.22e-55 Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase (EC 2.4.1.102) (EC 2.4.1.148) (EC 2.4.1.150) (C2GnT-mucin type) (C2GnT-M) Bovine herpesvirus 4 (BoHV-4) (Movar virus) protein glycosylation [GO:0006486] GO:0003829; GO:0006486; GO:0008109; GO:0016020; GO:0044178; GO:0106325; GO:0106326 23164 XM_029338447.2 2924 1604 1737 2643 2755 Q7PPA5 0 Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type (EC 7.2.2.10) (Calcium pump) (Sarcoplasmic/endoplasmic reticulum Ca(2+)-ATPase) Anopheles gambiae (African malaria mosquito) calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; ion transmembrane transport [GO:0034220] GO:0005388; GO:0005524; GO:0006874; GO:0015662; GO:0016020; GO:0016887; GO:0033017; GO:0034220; GO:0046872; GO:0070588 23165 XM_044314042.1 909 886 629 1207 1101 Q9BWT3 5.59e-85 Poly(A) polymerase gamma (PAP-gamma) (EC 2.7.7.19) (Neo-poly(A) polymerase) (Neo-PAP) (Polynucleotide adenylyltransferase gamma) (SRP RNA 3'-adenylating enzyme) (Signal recognition particle RNA-adenylating enzyme) (SRP RNA-adenylating enzyme) Homo sapiens (Human) mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631] GO:0003723; GO:0004652; GO:0005524; GO:0005634; GO:0005654; GO:0005829; GO:0006378; GO:0016020; GO:0016604; GO:0043631; GO:0046872 23166 XM_029330081.2 205 175 185 287 242 Q58DA6 2.09e-91 UDP-galactose translocator (Solute carrier family 35 member A2) (UDP-galactose transporter) (UDP-Gal-Tr) (UGT) Bos taurus (Bovine) carbohydrate transport [GO:0008643] GO:0000139; GO:0008643; GO:0015165 23167 XM_029350463.2 18 113 70 423 173 Q9H0Z9 7.04e-29 RNA-binding protein 38 (CLL-associated antigen KW-5) (HSRNASEB) (RNA-binding motif protein 38) (RNA-binding region-containing protein 1) (ssDNA-binding protein SEB4) Homo sapiens (Human) 3'-UTR-mediated mRNA stabilization [GO:0070935]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; mRNA processing [GO:0006397]; mRNA stabilization [GO:0048255]; negative regulation of cell population proliferation [GO:0008285]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of cell cycle [GO:0051726]; regulation of myotube differentiation [GO:0010830]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380] GO:0000381; GO:0003723; GO:0003729; GO:0003730; GO:0005634; GO:0005829; GO:0006397; GO:0006977; GO:0006978; GO:0007049; GO:0008285; GO:0008380; GO:0010830; GO:0030154; GO:0043484; GO:0048255; GO:0051726; GO:0070935 23168 XM_044318221.1 48 0 54 21 59 Q9BVH7 1e-23 Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 (EC 2.4.99.-) (GD1 alpha synthase) (GalNAc alpha-2,6-sialyltransferase V) (ST6GalNAc V) (ST6GalNAcV) (Sialyltransferase 7E) (SIAT7-E) Homo sapiens (Human) ganglioside biosynthetic process [GO:0001574]; glycosphingolipid biosynthetic process [GO:0006688]; oligosaccharide biosynthetic process [GO:0009312]; oligosaccharide metabolic process [GO:0009311]; protein glycosylation [GO:0006486] GO:0000139; GO:0001574; GO:0001665; GO:0006486; GO:0006688; GO:0008373; GO:0009311; GO:0009312 23169 XR_006393556.1 283 130 89 149 202 NA NA NA NA NA NA 23170 XR_006397851.1 9 0 1 7 8 NA NA NA NA NA NA 23171 XM_044310986.1 11 0 0 0 0 Q8CG08 1.09e-33 Collagen triple helix repeat-containing protein 1 Rattus norvegicus (Rat) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005581; GO:0005615; GO:0005737; GO:0016477; GO:0016528; GO:0017147; GO:0031012; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0090090; GO:0090103; GO:0090177 23172 XM_029355132.2 0 192 583 96 118 NA NA NA NA NA NA 23173 XM_029351441.2 40 12 58 33 59 NA NA NA NA NA NA 23174 XR_006391529.1 149 6 20 59 52 A7RZW4 0 Dipeptidyl peptidase 3 (EC 3.4.14.4) (Dipeptidyl aminopeptidase III) (Dipeptidyl arylamidase III) (Dipeptidyl peptidase III) (DPP III) Nematostella vectensis (Starlet sea anemone) proteolysis [GO:0006508] GO:0004177; GO:0005737; GO:0006508; GO:0008235; GO:0008239; GO:0046872 23175 XR_006392245.1 136 123 142 152 306 NA NA NA NA NA NA 23176 XM_029347607.2 476 480 581 621 298 Q8IS64 1.07e-155 Endothelin-converting enzyme homolog (ECE) (EC 3.4.24.-) Locusta migratoria (Migratory locust) proteolysis [GO:0006508] GO:0004175; GO:0004222; GO:0005886; GO:0006508; GO:0008270 23177 XM_029348032.2 4 13 5 15 0 NA NA NA NA NA NA 23178 XM_029329936.2 6 35 0 30 0 Q9NSA2 1.56e-64 Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) Homo sapiens (Human) potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005250; GO:0005886; GO:0008076; GO:0014069; GO:0016020; GO:0034765; GO:0043025; GO:0043197; GO:0045211; GO:0046872; GO:0051260; GO:0071805 23179 XM_044317917.1 123 73 131 265 252 O15439 0 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 23180 XR_006394950.1 1840 1945 1663 1552 1993 NA NA NA NA NA NA 23181 XM_029323579.2 1 5 6 12 8 NA NA NA NA NA NA 23182 XM_044309665.1 116 120 152 128 190 Q8NB78 0 Lysine-specific histone demethylase 2 (EC 1.14.99.66) (Flavin-containing amine oxidase domain-containing protein 1) (Lysine-specific histone demethylase 1B) Homo sapiens (Human) DNA methylation involved in gamete generation [GO:0043046]; histone H3-K4 demethylation [GO:0034720]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA methylation [GO:0044030]; regulation of gene expression by genomic imprinting [GO:0006349] GO:0000122; GO:0000786; GO:0003682; GO:0005634; GO:0005654; GO:0006349; GO:0008270; GO:0016491; GO:0032452; GO:0034720; GO:0042393; GO:0043046; GO:0044030; GO:0045944; GO:0050660; GO:0071949; GO:0140682 23183 XM_029352745.2 0 0 85 601 10 NA NA NA NA NA NA 23184 XM_044328697.1 859 718 321 519 192 Q3T075 4.41e-38 Syntaxin-8 Bos taurus (Bovine) intracellular protein transport [GO:0006886]; vesicle docking [GO:0048278]; vesicle fusion [GO:0006906] GO:0000149; GO:0005484; GO:0006886; GO:0006906; GO:0012505; GO:0016020; GO:0031201; GO:0048278 23185 XR_006392510.1 0 0 5 0 42 NA NA NA NA NA NA 23186 XM_044322092.1 242 48 240 316 723 Q07494 3.67e-24 Ephrin type-B receptor 1 (EC 2.7.10.1) (EPH-like kinase 6) (EK6) (cEK6) (Tyrosine-protein kinase receptor EPH-2) Gallus gallus (Chicken) axon guidance [GO:0007411]; cell chemotaxis [GO:0060326]; cell-substrate adhesion [GO:0031589]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; ephrin receptor signaling pathway [GO:0048013]; establishment of cell polarity [GO:0030010]; positive regulation of kinase activity [GO:0033674]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0004714; GO:0005005; GO:0005524; GO:0005886; GO:0007169; GO:0007411; GO:0030010; GO:0030425; GO:0031589; GO:0031901; GO:0033674; GO:0043005; GO:0043235; GO:0046328; GO:0046777; GO:0048013; GO:0051965; GO:0060326; GO:0060996; GO:0060997; GO:0070372 23187 XM_044325778.1 76 2 25 16 48 NA NA NA NA NA NA 23188 XM_044320153.1 283 123 175 410 154 Q9CXB8 3.31e-43 Alpha-protein kinase 1 (EC 2.7.11.1) Mus musculus (Mouse) cilium assembly [GO:0060271]; cytosolic pattern recognition receptor signaling pathway [GO:0002753]; innate immune response [GO:0045087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein phosphorylation [GO:0006468]; response to bacterium [GO:0009617] GO:0000922; GO:0002753; GO:0004674; GO:0005524; GO:0005813; GO:0005829; GO:0005929; GO:0006468; GO:0009617; GO:0032391; GO:0043123; GO:0045087; GO:0048029; GO:0060271; GO:0106310 23189 XM_044320153.1 283 123 175 410 154 Q9CXB8 1.1e-37 Alpha-protein kinase 1 (EC 2.7.11.1) Mus musculus (Mouse) cilium assembly [GO:0060271]; cytosolic pattern recognition receptor signaling pathway [GO:0002753]; innate immune response [GO:0045087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein phosphorylation [GO:0006468]; response to bacterium [GO:0009617] GO:0000922; GO:0002753; GO:0004674; GO:0005524; GO:0005813; GO:0005829; GO:0005929; GO:0006468; GO:0009617; GO:0032391; GO:0043123; GO:0045087; GO:0048029; GO:0060271; GO:0106310 23190 XM_029329077.2 82 378 0 395 0 A2RV61 2.95e-112 GTPase-activating protein and VPS9 domain-containing protein 1 Xenopus laevis (African clawed frog) endocytosis [GO:0006897]; regulation of GTPase activity [GO:0043087]; regulation of protein transport [GO:0051223] GO:0005085; GO:0005096; GO:0005768; GO:0005829; GO:0006897; GO:0016020; GO:0032794; GO:0043087; GO:0051223 23191 XM_029329077.2 82 378 0 395 0 A2RV61 7.71e-56 GTPase-activating protein and VPS9 domain-containing protein 1 Xenopus laevis (African clawed frog) endocytosis [GO:0006897]; regulation of GTPase activity [GO:0043087]; regulation of protein transport [GO:0051223] GO:0005085; GO:0005096; GO:0005768; GO:0005829; GO:0006897; GO:0016020; GO:0032794; GO:0043087; GO:0051223 23192 XM_029343304.2 302 287 241 363 344 Q9D0R9 1.9e-49 WD repeat-containing protein 89 Mus musculus (Mouse) corpus callosum development [GO:0022038]; ventricular system development [GO:0021591] GO:0021591; GO:0022038 23193 XM_044317647.1 78 35 8 75 81 Q66PG1 7.98e-42 Xylosyl- and glucuronyltransferase LARGE2s (EC 2.4.-.-) (Glycosyltransferase-like 1B) (LARGE xylosyl- and glucuronyltransferase 2) [Includes: Alpha-1,3-xylosyltransferase LARGE2 (EC 2.4.2.-); Beta-1,3-glucuronyltransferase LARGE2 (EC 2.4.1.-)] Danio rerio (Zebrafish) (Brachydanio rerio) protein glycosylation [GO:0006486]; protein O-linked mannosylation [GO:0035269] GO:0000139; GO:0005794; GO:0006486; GO:0015020; GO:0035269; GO:0042285; GO:0046872 23194 XM_029329534.2 440 337 259 469 485 Q80UK8 0 Integrator complex subunit 2 (Int2) Mus musculus (Mouse) snRNA 3'-end processing [GO:0034472]; snRNA processing [GO:0016180] GO:0005634; GO:0005737; GO:0016180; GO:0031965; GO:0032039; GO:0034472 23195 XM_029329534.2 440 337 259 469 485 Q80UK8 6.55e-73 Integrator complex subunit 2 (Int2) Mus musculus (Mouse) snRNA 3'-end processing [GO:0034472]; snRNA processing [GO:0016180] GO:0005634; GO:0005737; GO:0016180; GO:0031965; GO:0032039; GO:0034472 23196 XM_044325948.1 46 9 11 2 4 NA NA NA NA NA NA 23197 XR_006396932.1 0 65 0 0 58 NA NA NA NA NA NA 23198 XM_044321394.1 1 4 0 127 1 NA NA NA NA NA NA 23199 XM_044327887.1 0 0 0 0 24 Q8IUR7 4.59e-154 Armadillo repeat-containing protein 8 Homo sapiens (Human) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] GO:0000151; GO:0005576; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0034657; GO:0035580; GO:0043161; GO:0043231; GO:1904724 23200 XM_029356577.2 714 177 260 1002 594 Q08CH8 1.31e-112 Zinc finger TRAF-type-containing protein 1 (Cysteine and histidine-rich protein 1) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0046872; GO:0048471 23201 XR_006393907.1 41 2 25 5 151 NA NA NA NA NA NA 23202 XM_029348020.2 93 54 48 16 57 P36514 7.39e-67 UDP-glucuronosyltransferase 2C1 (UDPGT 2C1) (EC 2.4.1.17) Oryctolagus cuniculus (Rabbit) lipid metabolic process [GO:0006629] GO:0005789; GO:0006629; GO:0015020 23203 XR_006396068.1 3 11 1 2 1 NA NA NA NA NA NA 23204 XM_029350255.2 0 0 23 0 64 NA NA NA NA NA NA 23205 XM_029344231.2 1542 663 419 1368 847 A2A3L6 2.69e-55 Tetratricopeptide repeat protein 24 (TPR repeat protein 24) Homo sapiens (Human) NA NA 23206 XM_029330883.2 49 9 176 124 51 NA NA NA NA NA NA 23207 XM_044328122.1 2228 1876 1376 2560 2189 Q8N957 8.95e-129 Ankyrin repeat and fibronectin type-III domain-containing protein 1 Homo sapiens (Human) establishment of mitotic spindle orientation [GO:0000132]; regulation of establishment of bipolar cell polarity [GO:0061172] GO:0000132; GO:0005819; GO:0061172 23208 XM_044314518.1 55 7 15 11 31 NA NA NA NA NA NA 23209 XM_029336687.2 1683 935 934 1497 1294 O77633 0 Disintegrin and metalloproteinase domain-containing protein 10 (ADAM 10) (EC 3.4.24.81) (Kuzbanian protein homolog) (Mammalian disintegrin-metalloprotease) (CD antigen CD156c) Sus scrofa (Pig) adherens junction organization [GO:0034332]; cochlea development [GO:0090102]; constitutive protein ectodomain proteolysis [GO:0051089]; epidermal growth factor receptor ligand maturation [GO:0038004]; in utero embryonic development [GO:0001701]; membrane protein ectodomain proteolysis [GO:0006509]; monocyte activation [GO:0042117]; negative regulation of cell adhesion [GO:0007162]; negative regulation of gene expression [GO:0010629]; Notch signaling pathway [GO:0007219]; pore complex assembly [GO:0046931]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of T cell chemotaxis [GO:0010820]; postsynapse organization [GO:0099173]; protein catabolic process at postsynapse [GO:0140249]; protein phosphorylation [GO:0006468]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of Notch signaling pathway [GO:0008593]; regulation of postsynapse organization [GO:0099175]; regulation of vasculature development [GO:1901342]; response to tumor necrosis factor [GO:0034612]; toxin transport [GO:1901998] GO:0000139; GO:0001701; GO:0004175; GO:0004222; GO:0005634; GO:0005798; GO:0005886; GO:0005912; GO:0006468; GO:0006509; GO:0007162; GO:0007219; GO:0008284; GO:0008593; GO:0009986; GO:0010629; GO:0010820; GO:0014069; GO:0017124; GO:0019901; GO:0030136; GO:0030307; GO:0030424; GO:0030425; GO:0034332; GO:0034612; GO:0038004; GO:0042117; GO:0042803; GO:0046872; GO:0046930; GO:0046931; GO:0051089; GO:0070573; GO:0090102; GO:0097038; GO:0097060; GO:0097197; GO:0098696; GO:0098978; GO:0099173; GO:0099175; GO:0140249; GO:1901342; GO:1901998; GO:1902945 23210 XM_029326221.2 0 9 0 1 0 NA NA NA NA NA NA 23211 XM_029338399.2 10126 11173 8755 8432 4047 Q5U316 3.23e-105 Ras-related protein Rab-35 Rattus norvegicus (Rat) antigen processing and presentation [GO:0019882]; cellular response to nerve growth factor stimulus [GO:1990090]; endocytic recycling [GO:0032456]; endosomal transport [GO:0016197]; mitotic cytokinesis [GO:0000281]; neuron projection development [GO:0031175]; plasma membrane to endosome transport [GO:0048227]; protein localization [GO:0008104]; protein localization to endosome [GO:0036010]; protein transport [GO:0015031]; Rab protein signal transduction [GO:0032482]; vesicle-mediated transport [GO:0016192] GO:0000281; GO:0003924; GO:0005525; GO:0005546; GO:0005886; GO:0005905; GO:0008104; GO:0010008; GO:0015031; GO:0016192; GO:0016197; GO:0019003; GO:0019882; GO:0030672; GO:0031175; GO:0031253; GO:0032456; GO:0032482; GO:0036010; GO:0042470; GO:0045171; GO:0045334; GO:0048227; GO:1990090 23212 XM_044322234.1 1 13 0 21 2 NA NA NA NA NA NA 23213 XM_044328594.1 209 364 401 347 161 P08478 6.27e-141 Peptidyl-glycine alpha-amidating monooxygenase A (PAM-A) (Peptide C-terminal alpha-amidating enzyme I) (AE-I) (Peptidyl-glycine alpha-amidating monooxygenase I) [Includes: Peptidylglycine alpha-hydroxylating monooxygenase A (PHM-A) (EC 1.14.17.3); Peptidyl-alpha-hydroxyglycine alpha-amidating lyase A (EC 4.3.2.5) (Peptidylamidoglycolate lyase-A) (PAL-A)] Xenopus laevis (African clawed frog) peptide metabolic process [GO:0006518] GO:0004504; GO:0004598; GO:0005507; GO:0006518; GO:0030658 23214 XM_029345118.2 370 308 220 224 314 Q9WTN0 1.13e-142 Geranylgeranyl pyrophosphate synthase (GGPP synthase) (GGPPSase) (EC 2.5.1.-) ((2E,6E)-farnesyl diphosphate synthase) (Dimethylallyltranstransferase) (EC 2.5.1.1) (Farnesyl diphosphate synthase) (Farnesyltranstransferase) (EC 2.5.1.29) (Geranylgeranyl diphosphate synthase) (Geranyltranstransferase) (EC 2.5.1.10) Mus musculus (Mouse) farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; geranylgeranyl diphosphate biosynthetic process [GO:0033386]; isoprenoid biosynthetic process [GO:0008299]; isoprenoid metabolic process [GO:0006720] GO:0004161; GO:0004311; GO:0004337; GO:0004659; GO:0005654; GO:0005737; GO:0005829; GO:0006720; GO:0008299; GO:0030018; GO:0033384; GO:0033386; GO:0042802; GO:0045337; GO:0046872; GO:0048471 23215 XR_006393578.1 37 29 38 28 81 NA NA NA NA NA NA 23216 XM_029354348.2 2379 1933 1423 2209 2330 Q8C9S4 6.14e-116 Coiled-coil domain-containing protein 186 (Oocyte-testis gene 1 protein) Mus musculus (Mouse) glucose homeostasis [GO:0042593]; insulin secretion involved in cellular response to glucose stimulus [GO:0035773]; response to bacterium [GO:0009617]; vesicle cytoskeletal trafficking [GO:0099518] GO:0005794; GO:0005802; GO:0009617; GO:0031267; GO:0035773; GO:0042593; GO:0099518 23217 XM_044313438.1 64 47 0 0 10 NA NA NA NA NA NA 23218 XM_044308249.1 49 2 28 22 46 NA NA NA NA NA NA 23219 XM_044321332.1 29 0 46 0 31 P46023 2.1e-89 G-protein coupled receptor GRL101 Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004930; GO:0005886 23220 XM_044307482.1 0 0 8 0 1 O70444 7.63e-59 Serine/threonine-protein kinase pim-3 (EC 2.7.11.1) (Kinase induced by depolarization) (Protein kinase Kid-1) Rattus norvegicus (Rat) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cellular response to forskolin [GO:1904322]; negative regulation of apoptotic process [GO:0043066]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of mitotic cell cycle [GO:0007346] GO:0004674; GO:0005524; GO:0005737; GO:0006468; GO:0006915; GO:0007049; GO:0007346; GO:0043066; GO:0046777; GO:0061179; GO:0106310; GO:1904322 23221 XM_044320984.1 0 0 0 6 0 NA NA NA NA NA NA 23222 XM_044325787.1 1 30 30 0 36 P70490 1.84e-21 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 23223 XM_029353864.2 92 19 131 38 206 NA NA NA NA NA NA 23224 XM_044311035.1 3 0 32 2 60 NA NA NA NA NA NA 23225 XM_029348126.2 1321 877 519 2073 562 NA NA NA NA NA NA 23226 XM_029345903.2 847 1083 771 1548 780 NA NA NA NA NA NA 23227 XM_044325076.1 21 14 2 4 14 NA NA NA NA NA NA 23228 XM_044325389.1 72 75 93 33 209 P27590 3.6e-30 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Rattus norvegicus (Rat) antibacterial innate immune response [GO:0140367]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; autophagy [GO:0006914]; calcium ion homeostasis [GO:0055074]; cellular calcium ion homeostasis [GO:0006874]; cellular chloride ion homeostasis [GO:0030644]; cellular phosphate ion homeostasis [GO:0030643]; cellular response to unfolded protein [GO:0034620]; cellular sodium ion homeostasis [GO:0006883]; chaperone-mediated protein folding [GO:0061077]; chemical homeostasis [GO:0048878]; chloride ion homeostasis [GO:0055064]; citric acid secretion [GO:0046720]; collecting duct development [GO:0072044]; connective tissue replacement [GO:0097709]; creatinine homeostasis [GO:0097273]; defense response to Gram-negative bacterium [GO:0050829]; endoplasmic reticulum organization [GO:0007029]; gene expression [GO:0010467]; glomerular filtration [GO:0003094]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; ion homeostasis [GO:0050801]; juxtaglomerular apparatus development [GO:0072051]; kidney development [GO:0001822]; leukocyte cell-cell adhesion [GO:0007159]; lipid metabolic process [GO:0006629]; loop of Henle development [GO:0072070]; metanephric ascending thin limb development [GO:0072218]; metanephric distal convoluted tubule development [GO:0072221]; metanephric thick ascending limb development [GO:0072233]; micturition [GO:0060073]; multicellular organismal homeostasis [GO:0048871]; multicellular organismal response to stress [GO:0033555]; neutrophil migration [GO:1990266]; organ or tissue specific immune response [GO:0002251]; peptidyl-threonine phosphorylation [GO:0018107]; phosphate ion homeostasis [GO:0055062]; potassium ion homeostasis [GO:0055075]; protein localization to vacuole [GO:0072665]; protein phosphorylation [GO:0006468]; protein transport into plasma membrane raft [GO:0044861]; regulation of blood pressure [GO:0008217]; regulation of protein transport [GO:0051223]; regulation of urine volume [GO:0035809]; renal sodium ion absorption [GO:0070294]; renal urate salt excretion [GO:0097744]; renal water homeostasis [GO:0003091]; response to endoplasmic reticulum stress [GO:0034976]; response to lipopolysaccharide [GO:0032496]; response to organic substance [GO:0010033]; response to unfolded protein [GO:0006986]; response to water deprivation [GO:0009414]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; sodium ion homeostasis [GO:0055078]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; ubiquitin-dependent ERAD pathway [GO:0030433]; urate transport [GO:0015747]; urea transmembrane transport [GO:0071918]; water homeostasis [GO:0030104] GO:0000922; GO:0001822; GO:0002251; GO:0003091; GO:0003094; GO:0005201; GO:0005509; GO:0005615; GO:0005783; GO:0005794; GO:0005886; GO:0005929; GO:0006468; GO:0006629; GO:0006874; GO:0006883; GO:0006914; GO:0006915; GO:0006954; GO:0006986; GO:0007029; GO:0007157; GO:0007159; GO:0008217; GO:0008380; GO:0009410; GO:0009414; GO:0009986; GO:0010033; GO:0010467; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0018107; GO:0019864; GO:0030104; GO:0030433; GO:0030643; GO:0030644; GO:0031410; GO:0032496; GO:0033209; GO:0033555; GO:0034620; GO:0034976; GO:0035809; GO:0044861; GO:0045121; GO:0045177; GO:0046720; GO:0048871; GO:0048878; GO:0050801; GO:0050829; GO:0051223; GO:0055062; GO:0055064; GO:0055074; GO:0055075; GO:0055078; GO:0060073; GO:0060170; GO:0061077; GO:0070294; GO:0071918; GO:0072044; GO:0072051; GO:0072070; GO:0072218; GO:0072221; GO:0072233; GO:0072665; GO:0097190; GO:0097273; GO:0097709; GO:0097744; GO:0140367; GO:1990266 23229 XM_029338441.2 547 444 254 385 288 A4FUP9 6.29e-95 Glycosyltransferase 1 domain-containing protein 1 (EC 2.4.-.-) Mus musculus (Mouse) NA GO:0005576; GO:0005829; GO:0016757 23230 XR_006392621.1 2 41 13 55 11 NA NA NA NA NA NA 23231 XM_044323785.1 2176 2771 719 1886 1824 NA NA NA NA NA NA 23232 XM_029348364.2 1068 46 411 276 0 Q9V3D5 4.28e-38 Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1) (Protein smell impaired at 35A) (dDyrk2) Drosophila melanogaster (Fruit fly) olfactory behavior [GO:0042048]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of Wnt signaling pathway [GO:0030177]; protein phosphorylation [GO:0006468]; response to light stimulus [GO:0009416]; sensory perception of smell [GO:0007608] GO:0004674; GO:0004712; GO:0004713; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0005856; GO:0006468; GO:0007608; GO:0009416; GO:0018105; GO:0018107; GO:0030177; GO:0042048; GO:0106310 23233 XM_029355606.2 53 104 20 112 87 NA NA NA NA NA NA 23234 XM_029332018.2 1429 483 988 702 980 Q28811 0 Deoxyribodipyrimidine photo-lyase (EC 4.1.99.3) (DNA photolyase) (Photoreactivating enzyme) Potorous tridactylus (Potoroo) DNA repair [GO:0006281] GO:0003677; GO:0003904; GO:0006281 23235 XM_029333340.2 0 76 52 129 124 Q8TEB9 3.36e-52 Rhomboid-related protein 4 (RRP4) (EC 3.4.21.105) (Rhomboid domain-containing protein 1) (Rhomboid-like protein 4) Homo sapiens (Human) apoptotic process [GO:0006915]; cellular response to unfolded protein [GO:0034620]; cellular response to UV [GO:0034644]; ERAD pathway [GO:0036503]; membrane protein intracellular domain proteolysis [GO:0031293]; membrane protein proteolysis [GO:0033619]; membrane protein proteolysis involved in retrograde protein transport, ER to cytosol [GO:1904211]; negative regulation of apoptotic process [GO:0043066]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein processing [GO:0010954]; positive regulation of secretion [GO:0051047]; post-translational protein modification [GO:0043687]; spermatid differentiation [GO:0048515] GO:0004175; GO:0004252; GO:0005783; GO:0005789; GO:0006915; GO:0010954; GO:0031293; GO:0031966; GO:0033619; GO:0034620; GO:0034644; GO:0036503; GO:0043066; GO:0043687; GO:0044322; GO:0045732; GO:0048515; GO:0051047; GO:1904211 23236 XM_044307057.1 15 23 0 17 11 Q7LHG5 8.21e-79 Transposon Ty3-I Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-2 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p52 (IN); Integrase p49 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 23237 XM_044316713.1 89 13 95 44 147 P14381 3.67e-42 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 23238 XM_029336303.2 0 3 19 0 58 Q8BJ56 1.46e-72 Patatin-like phospholipase domain-containing protein 2 (EC 3.1.1.3) (Adipose triglyceride lipase) (Calcium-independent phospholipase A2-zeta) (iPLA2-zeta) (EC 3.1.1.4) (Desnutrin) Mus musculus (Mouse) cellular lipid catabolic process [GO:0044242]; diacylglycerol biosynthetic process [GO:0006651]; lipid droplet disassembly [GO:1905691]; lipid droplet organization [GO:0034389]; lipid homeostasis [GO:0055088]; lipid storage [GO:0019915]; negative regulation of sequestering of triglyceride [GO:0010891]; positive regulation of triglyceride catabolic process [GO:0010898]; triglyceride catabolic process [GO:0019433] GO:0004623; GO:0004806; GO:0005654; GO:0005737; GO:0005811; GO:0005829; GO:0005886; GO:0006651; GO:0010891; GO:0010898; GO:0016020; GO:0016411; GO:0019433; GO:0019915; GO:0034389; GO:0044242; GO:0050253; GO:0051264; GO:0051265; GO:0055088; GO:1905691 23239 XM_044310649.1 6 0 0 0 1 NA NA NA NA NA NA 23240 XM_029344470.2 439 300 270 290 273 NA NA NA NA NA NA 23241 XM_029348111.2 6049 9161 6027 6300 4098 NA NA NA NA NA NA 23242 XM_029340077.2 0 6 2 8 5 NA NA NA NA NA NA 23243 XR_003826009.2 799 240 206 281 70 NA NA NA NA NA NA 23244 XR_006392042.1 28 0 0 1 79 NA NA NA NA NA NA 23245 XM_029353002.2 10 13 21 17 13 NA NA NA NA NA NA 23246 XM_044328287.1 0 31 0 0 32 NA NA NA NA NA NA 23247 XM_029343390.2 44 141 0 123 18 NA NA NA NA NA NA 23248 XM_044318327.1 1 6 15 2 4 NA NA NA NA NA NA 23249 XR_006396808.1 0 0 0 12 0 Q9UKV8 0 Protein argonaute-2 (Argonaute2) (hAgo2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (PAZ Piwi domain protein) (PPD) (Protein slicer) Homo sapiens (Human) miRNA metabolic process [GO:0010586]; miRNA processing [GO:0035196]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; miRNA-mediated gene silencing by mRNA destabilization [GO:0035279]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; negative regulation of translational initiation [GO:0045947]; positive regulation of angiogenesis [GO:0045766]; positive regulation of gene expression [GO:0010628]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of trophoblast cell migration [GO:1901165]; post-embryonic development [GO:0009791]; pre-miRNA processing [GO:0031054]; RISC complex assembly [GO:0070922]; RNA secondary structure unwinding [GO:0010501]; RNA-mediated gene silencing [GO:0031047]; RNA-mediated post-transcriptional gene silencing [GO:0035194]; siRNA processing [GO:0030422]; siRNA-mediated gene silencing by mRNA destabilization [GO:0090625]; translation [GO:0006412] GO:0000340; GO:0000932; GO:0000993; GO:0001046; GO:0003723; GO:0003725; GO:0003727; GO:0003743; GO:0004521; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005844; GO:0005845; GO:0006412; GO:0008022; GO:0009791; GO:0010501; GO:0010586; GO:0010628; GO:0016020; GO:0016442; GO:0030422; GO:0030425; GO:0031047; GO:0031054; GO:0035194; GO:0035196; GO:0035197; GO:0035198; GO:0035278; GO:0035279; GO:0036464; GO:0042985; GO:0045766; GO:0045944; GO:0045947; GO:0046872; GO:0060213; GO:0070062; GO:0070551; GO:0070578; GO:0070922; GO:0090624; GO:0090625; GO:0098808; GO:1900153; GO:1901165; GO:1990904 23250 XM_029351866.2 515 328 452 384 1236 P51948 1.89e-80 CDK-activating kinase assembly factor MAT1 (CDK7/cyclin-H assembly factor) (Cyclin-G1-interacting protein) (Menage a trois) (RING finger protein 66) (RING finger protein MAT1) (p35) (p36) Homo sapiens (Human) adult heart development [GO:0007512]; DNA repair [GO:0006281]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA helicase activity [GO:1905775]; nucleotide-excision repair [GO:0006289]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein-containing complex assembly [GO:0065003]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; transcription by RNA polymerase II [GO:0006366]; ventricular system development [GO:0021591] GO:0000079; GO:0000082; GO:0000439; GO:0005654; GO:0005675; GO:0006281; GO:0006289; GO:0006357; GO:0006366; GO:0007512; GO:0008270; GO:0019907; GO:0021591; GO:0043066; GO:0045737; GO:0047485; GO:0048661; GO:0051592; GO:0061575; GO:0065003; GO:0070516; GO:0070985; GO:1905775; GO:2000045 23251 XM_044325608.1 31 40 11 14 31 NA NA NA NA NA NA 23252 XM_044318289.1 263 163 147 214 253 Q6WBX8 2.31e-74 Cell cycle checkpoint control protein RAD9B (DNA repair exonuclease rad9 homolog B) (hRAD9B) Homo sapiens (Human) cellular response to ionizing radiation [GO:0071479]; DNA repair [GO:0006281]; DNA replication checkpoint signaling [GO:0000076]; mitotic intra-S DNA damage checkpoint signaling [GO:0031573] GO:0000076; GO:0005634; GO:0005654; GO:0006281; GO:0030896; GO:0031573; GO:0071479 23253 XM_029346132.2 590 327 216 357 338 Q5EAC5 8.95e-68 Zinc finger protein 410 Bos taurus (Bovine) regulation of transcription by RNA polymerase II [GO:0006357] GO:0003677; GO:0003712; GO:0005634; GO:0005694; GO:0006357; GO:0046872 23254 XM_029346132.2 590 327 216 357 338 Q5EAC5 7.64e-28 Zinc finger protein 410 Bos taurus (Bovine) regulation of transcription by RNA polymerase II [GO:0006357] GO:0003677; GO:0003712; GO:0005634; GO:0005694; GO:0006357; GO:0046872 23255 XM_029330988.2 238 301 121 284 184 A7RR34 3.6e-50 Protein Flattop homolog (Cilia- and flagella-associated protein 126) Nematostella vectensis (Starlet sea anemone) cilium organization [GO:0044782] GO:0005737; GO:0005929; GO:0016324; GO:0036064; GO:0044782 23256 XM_044323409.1 401 273 177 209 234 A7RWD2 1.61e-115 Probable cytosolic iron-sulfur protein assembly protein CIAO1 homolog Nematostella vectensis (Starlet sea anemone) iron-sulfur cluster assembly [GO:0016226] GO:0016226; GO:0097361 23257 XM_044323409.1 401 273 177 209 234 A7RWD2 2.29e-24 Probable cytosolic iron-sulfur protein assembly protein CIAO1 homolog Nematostella vectensis (Starlet sea anemone) iron-sulfur cluster assembly [GO:0016226] GO:0016226; GO:0097361 23258 XM_029351543.2 1361 1245 806 1658 1445 P11498 0 Pyruvate carboxylase, mitochondrial (EC 6.4.1.1) (Pyruvic carboxylase) (PCB) Homo sapiens (Human) gluconeogenesis [GO:0006094]; lipid metabolic process [GO:0006629]; NADH metabolic process [GO:0006734]; NADP metabolic process [GO:0006739]; negative regulation of gene expression [GO:0010629]; positive regulation by host of viral process [GO:0044794]; pyruvate metabolic process [GO:0006090]; viral release from host cell [GO:0019076]; viral RNA genome packaging [GO:0019074] GO:0004736; GO:0005524; GO:0005737; GO:0005739; GO:0005759; GO:0005829; GO:0006090; GO:0006094; GO:0006629; GO:0006734; GO:0006739; GO:0009374; GO:0010629; GO:0019074; GO:0019076; GO:0042802; GO:0044794; GO:0046872 23259 XM_044309539.1 10 15 8 17 42 NA NA NA NA NA NA 23260 XR_006396014.1 58 39 29 64 45 Q9NR16 3.23e-69 Scavenger receptor cysteine-rich type 1 protein M160 (CD163 antigen-like 1) (CD antigen CD163b) Homo sapiens (Human) NA GO:0005044; GO:0005576; GO:0009897 23261 XR_006396014.1 58 39 29 64 45 Q9NR16 5.79e-63 Scavenger receptor cysteine-rich type 1 protein M160 (CD163 antigen-like 1) (CD antigen CD163b) Homo sapiens (Human) NA GO:0005044; GO:0005576; GO:0009897 23262 XR_006396014.1 58 39 29 64 45 Q9NR16 3.32e-57 Scavenger receptor cysteine-rich type 1 protein M160 (CD163 antigen-like 1) (CD antigen CD163b) Homo sapiens (Human) NA GO:0005044; GO:0005576; GO:0009897 23263 XR_006396014.1 58 39 29 64 45 Q9NR16 1.57e-51 Scavenger receptor cysteine-rich type 1 protein M160 (CD163 antigen-like 1) (CD antigen CD163b) Homo sapiens (Human) NA GO:0005044; GO:0005576; GO:0009897 23264 XR_006396014.1 58 39 29 64 45 Q9NR16 3.82e-51 Scavenger receptor cysteine-rich type 1 protein M160 (CD163 antigen-like 1) (CD antigen CD163b) Homo sapiens (Human) NA GO:0005044; GO:0005576; GO:0009897 23265 XR_006396014.1 58 39 29 64 45 Q9NR16 2.08e-31 Scavenger receptor cysteine-rich type 1 protein M160 (CD163 antigen-like 1) (CD antigen CD163b) Homo sapiens (Human) NA GO:0005044; GO:0005576; GO:0009897 23266 XM_029328717.2 34 14 32 49 53 NA NA NA NA NA NA 23267 XM_044321442.1 126 94 201 172 482 Q8STF6 1.93e-43 Dystrophin-like protein 1 (Dyb-1-binding and CAPON-related protein) Caenorhabditis elegans locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; positive regulation of locomotion [GO:0040017]; regulation of oviposition [GO:0046662]; sarcomere organization [GO:0045214] GO:0007626; GO:0008307; GO:0016010; GO:0030235; GO:0030424; GO:0040017; GO:0045214; GO:0046662; GO:0046716; GO:0050998; GO:0055120 23268 XM_044324922.1 1079 238 518 602 1074 Q9UQ26 3.19e-63 Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2) (Rab-3-interacting protein 3) Homo sapiens (Human) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-ion regulated exocytosis [GO:0017156]; cell differentiation [GO:0030154]; insulin secretion [GO:0030073]; intracellular protein transport [GO:0006886]; positive regulation of dendrite extension [GO:1903861]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of synaptic transmission [GO:0050806]; regulation of exocytosis [GO:0017157]; regulation of membrane potential [GO:0042391]; regulation of synaptic plasticity [GO:0048167]; spontaneous neurotransmitter secretion [GO:0061669] GO:0006886; GO:0007188; GO:0017156; GO:0017157; GO:0030073; GO:0030154; GO:0031267; GO:0042391; GO:0042734; GO:0042995; GO:0044325; GO:0046872; GO:0048167; GO:0048786; GO:0048788; GO:0048791; GO:0050806; GO:0061669; GO:0070062; GO:0097151; GO:1903861; GO:2000463 23269 XM_044324922.1 1079 238 518 602 1074 Q9UQ26 1.83e-30 Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2) (Rab-3-interacting protein 3) Homo sapiens (Human) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-ion regulated exocytosis [GO:0017156]; cell differentiation [GO:0030154]; insulin secretion [GO:0030073]; intracellular protein transport [GO:0006886]; positive regulation of dendrite extension [GO:1903861]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of synaptic transmission [GO:0050806]; regulation of exocytosis [GO:0017157]; regulation of membrane potential [GO:0042391]; regulation of synaptic plasticity [GO:0048167]; spontaneous neurotransmitter secretion [GO:0061669] GO:0006886; GO:0007188; GO:0017156; GO:0017157; GO:0030073; GO:0030154; GO:0031267; GO:0042391; GO:0042734; GO:0042995; GO:0044325; GO:0046872; GO:0048167; GO:0048786; GO:0048788; GO:0048791; GO:0050806; GO:0061669; GO:0070062; GO:0097151; GO:1903861; GO:2000463 23270 XM_029330338.2 2910 2669 1481 1907 2126 Q9VPH8 0 Retinoblastoma-binding protein 5 homolog Drosophila melanogaster (Fruit fly) chromatin organization [GO:0006325]; histone H3-K4 methylation [GO:0051568] GO:0006325; GO:0044665; GO:0044666; GO:0048188; GO:0051568 23271 XM_029341705.2 229 182 262 304 503 P32929 7.34e-168 Cystathionine gamma-lyase (CGL) (CSE) (EC 4.4.1.1) (Cysteine desulfhydrase) (Cysteine-protein sulfhydrase) (Gamma-cystathionase) (Homocysteine desulfhydrase) (EC 4.4.1.2) Homo sapiens (Human) cellular response to leukemia inhibitory factor [GO:1990830]; cysteine biosynthetic process [GO:0019344]; cysteine biosynthetic process via cystathionine [GO:0019343]; cysteine metabolic process [GO:0006534]; endoplasmic reticulum unfolded protein response [GO:0030968]; hydrogen sulfide biosynthetic process [GO:0070814]; lipid metabolic process [GO:0006629]; negative regulation of apoptotic signaling pathway [GO:2001234]; positive regulation of aortic smooth muscle cell differentiation [GO:1904831]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein homotetramerization [GO:0051289]; protein sulfhydration [GO:0044524]; protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine [GO:0018272]; transsulfuration [GO:0019346] GO:0004123; GO:0005516; GO:0005737; GO:0005829; GO:0006534; GO:0006629; GO:0016846; GO:0018272; GO:0019343; GO:0019344; GO:0019346; GO:0030170; GO:0030968; GO:0042802; GO:0043123; GO:0044524; GO:0044540; GO:0047982; GO:0051092; GO:0051289; GO:0070062; GO:0070814; GO:0080146; GO:0098606; GO:1904831; GO:1990830; GO:2001234 23272 XR_003825148.2 54 36 81 35 123 NA NA NA NA NA NA 23273 XM_044325467.1 67 15 19 38 22 NA NA NA NA NA NA 23274 XM_044311769.1 26 0 19 4 41 NA NA NA NA NA NA 23275 XM_029337762.2 900 386 590 988 1011 P18956 6.43e-24 Glutathione hydrolase proenzyme (EC 3.4.19.13) (Gamma-glutamyltranspeptidase proenzyme) (GGT) (EC 2.3.2.2) [Cleaved into: Glutathione hydrolase large chain; Glutathione hydrolase small chain] Escherichia coli (strain K12) amino acid salvage [GO:0043102]; glutathione biosynthetic process [GO:0006750]; glutathione catabolic process [GO:0006751]; self proteolysis [GO:0097264] GO:0006750; GO:0006751; GO:0030288; GO:0034722; GO:0036374; GO:0042597; GO:0043102; GO:0097264; GO:0102953; GO:0103068 23276 XM_044319430.1 5 4 7 13 21 Q8N2G6 3.69e-49 Zinc finger CCHC domain-containing protein 24 Homo sapiens (Human) NA GO:0003723; GO:0008270 23277 XR_003827377.2 123 118 120 112 101 NA NA NA NA NA NA 23278 XM_044321192.1 150 69 91 316 116 Q8SX37 3.33e-21 CDP-diacylglycerol--inositol 3-phosphatidyltransferase (CDIPT) (EC 2.7.8.11) (Phosphatidylinositol synthase) Drosophila melanogaster (Fruit fly) basement membrane organization [GO:0071711]; phosphatidylinositol biosynthetic process [GO:0006661]; phototransduction [GO:0007602] GO:0003881; GO:0005794; GO:0006661; GO:0007602; GO:0016324; GO:0016328; GO:0046872; GO:0071711 23279 XM_029340101.2 50 107 47 48 39 NA NA NA NA NA NA 23280 XM_029340189.2 207 83 132 443 52 Q05096 0 Unconventional myosin-Ib (Myosin I alpha) (MMI-alpha) (MMIa) (Myosin heavy chain myr 1) Rattus norvegicus (Rat) actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; actin filament-based movement [GO:0030048]; nervous system development [GO:0007399]; post-Golgi vesicle-mediated transport [GO:0006892]; transferrin transport [GO:0033572]; vesicle transport along actin filament [GO:0030050] GO:0000146; GO:0003774; GO:0003779; GO:0005516; GO:0005524; GO:0005546; GO:0005547; GO:0005737; GO:0005769; GO:0005884; GO:0005886; GO:0005902; GO:0005903; GO:0006892; GO:0007015; GO:0007399; GO:0010008; GO:0015629; GO:0016459; GO:0030048; GO:0030050; GO:0030175; GO:0031982; GO:0032588; GO:0033572; GO:0045177; GO:0048471; GO:0051015; GO:0051017; GO:0071944 23281 XM_029340189.2 207 83 132 443 52 Q05096 9.3e-61 Unconventional myosin-Ib (Myosin I alpha) (MMI-alpha) (MMIa) (Myosin heavy chain myr 1) Rattus norvegicus (Rat) actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; actin filament-based movement [GO:0030048]; nervous system development [GO:0007399]; post-Golgi vesicle-mediated transport [GO:0006892]; transferrin transport [GO:0033572]; vesicle transport along actin filament [GO:0030050] GO:0000146; GO:0003774; GO:0003779; GO:0005516; GO:0005524; GO:0005546; GO:0005547; GO:0005737; GO:0005769; GO:0005884; GO:0005886; GO:0005902; GO:0005903; GO:0006892; GO:0007015; GO:0007399; GO:0010008; GO:0015629; GO:0016459; GO:0030048; GO:0030050; GO:0030175; GO:0031982; GO:0032588; GO:0033572; GO:0045177; GO:0048471; GO:0051015; GO:0051017; GO:0071944 23282 XM_044315380.1 28 4 0 19 29 NA NA NA NA NA NA 23283 XM_044326157.1 193 92 126 64 407 Q8BKG3 1.23e-63 Inactive tyrosine-protein kinase 7 (Protein chuzhoi) (Protein-tyrosine kinase 7) (Pseudo tyrosine kinase receptor 7) (Tyrosine-protein kinase-like 7) Mus musculus (Mouse) actin cytoskeleton reorganization [GO:0031532]; axis elongation [GO:0003401]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to retinoic acid [GO:0071300]; cochlea morphogenesis [GO:0090103]; convergent extension [GO:0060026]; coronary vasculature development [GO:0060976]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of planar polarity [GO:0001736]; heart development [GO:0007507]; kidney development [GO:0001822]; lung-associated mesenchyme development [GO:0060484]; neural tube closure [GO:0001843]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of neuron projection development [GO:0010976]; regulation of canonical Wnt signaling pathway [GO:0060828]; ventricular septum development [GO:0003281]; wound healing [GO:0042060] GO:0001736; GO:0001822; GO:0001843; GO:0003281; GO:0003401; GO:0005886; GO:0005911; GO:0007155; GO:0007507; GO:0010976; GO:0016020; GO:0016477; GO:0031532; GO:0042060; GO:0045198; GO:0050839; GO:0060026; GO:0060484; GO:0060828; GO:0060976; GO:0071300; GO:0090103; GO:0090179; GO:0090263 23284 XM_044317575.1 5 341 115 218 215 NA NA NA NA NA NA 23285 XM_029350378.2 369 370 438 414 521 Q5W0Q7 6.05e-33 SUMO-specific isopeptidase USPL1 (EC 3.4.22.-) (Ubiquitin-specific peptidase-like protein 1) (USP-like 1) Homo sapiens (Human) Cajal body organization [GO:0030576]; cell population proliferation [GO:0008283]; protein desumoylation [GO:0016926]; snRNA transcription [GO:0009301] GO:0005615; GO:0008283; GO:0009301; GO:0015030; GO:0016926; GO:0016929; GO:0030576; GO:0032183 23286 XM_044329221.1 25 23 30 31 144 NA NA NA NA NA NA 23287 XR_006398015.1 992 379 501 763 430 Q5R1W5 5.99e-42 Serine/arginine-rich splicing factor 2 (Splicing component, 35 kDa) (Splicing factor SC35) (SC-35) (Splicing factor, arginine/serine-rich 2) Pan troglodytes (Chimpanzee) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0003723; GO:0006397; GO:0008380; GO:0016607 23288 XM_029339991.2 52 15 13 32 94 P11009 0 Creatine kinase S-type, mitochondrial (EC 2.7.3.2) (Basic-type mitochondrial creatine kinase) (Mib-CK) (Sarcomeric mitochondrial creatine kinase) (S-MtCK) Gallus gallus (Chicken) phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310] GO:0004111; GO:0005524; GO:0005743; GO:0016310; GO:0046314 23289 XM_044320387.1 903 567 419 707 582 Q3UTQ8 2.11e-154 Cyclin-dependent kinase-like 5 (EC 2.7.11.22) Mus musculus (Mouse) modulation of chemical synaptic transmission [GO:0050804]; neuron migration [GO:0001764]; positive regulation of axon extension [GO:0045773]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of GTPase activity [GO:0043547]; protein autophosphorylation [GO:0046777]; protein localization to nucleus [GO:0034504]; protein phosphorylation [GO:0006468]; regulation of cilium assembly [GO:1902017]; regulation of dendrite development [GO:0050773]; regulation of postsynapse organization [GO:0099175] GO:0001764; GO:0004672; GO:0004693; GO:0005524; GO:0005634; GO:0005654; GO:0005813; GO:0006468; GO:0016301; GO:0031267; GO:0032587; GO:0032839; GO:0034504; GO:0036064; GO:0043547; GO:0044294; GO:0045202; GO:0045773; GO:0046777; GO:0048471; GO:0050773; GO:0050775; GO:0050804; GO:0060999; GO:0097542; GO:0098978; GO:0099092; GO:0099175; GO:0106310; GO:1902017 23290 XM_029327413.2 3287 2842 1751 2513 2435 Q5E9Q4 3.22e-86 Adaptin ear-binding coat-associated protein 2 (NECAP endocytosis-associated protein 2) (NECAP-2) Bos taurus (Bovine) endocytosis [GO:0006897]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] GO:0005886; GO:0006897; GO:0015031; GO:0016192; GO:0030125 23291 XM_044325985.1 133 0 201 0 0 NA NA NA NA NA NA 23292 XM_029336645.2 32 45 51 63 92 NA NA NA NA NA NA 23293 XM_029323974.2 911 548 295 664 386 Q9JK72 1.05e-99 Copper chaperone for superoxide dismutase (Superoxide dismutase copper chaperone) Rattus norvegicus (Rat) positive regulation of oxidoreductase activity [GO:0051353]; removal of superoxide radicals [GO:0019430] GO:0005507; GO:0005634; GO:0005737; GO:0016532; GO:0019430; GO:0019899; GO:0051353 23294 XM_029333641.2 45 43 13 63 57 A0JPI9 4.23e-49 Leucine-rich repeat-containing protein 74A (Leucine-rich repeat-containing protein 74) Rattus norvegicus (Rat) NA NA 23295 XM_029342510.2 2977 2320 1514 2272 1127 Q3T197 5.22e-71 STING ER exit protein (STEEP) Bos taurus (Bovine) endoplasmic reticulum membrane organization [GO:0090158]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888] GO:0005634; GO:0005737; GO:0006888; GO:0044297; GO:0090158 23296 XM_044329214.1 10 4 55 2 11 NA NA NA NA NA NA 23297 XM_029358174.2 243 152 0 585 12 Q6REY9 8.68e-98 Rho GTPase-activating protein 20 (RA and RhoGAP domain-containing protein) (RARhoGAP) (Rho-type GTPase-activating protein 20) Rattus norvegicus (Rat) regulation of Rho protein signal transduction [GO:0035023]; signal transduction [GO:0007165] GO:0005096; GO:0007165; GO:0031267; GO:0035023 23298 XM_029347917.2 0 55 477 89 16 P97779 5.75e-26 Hyaluronan-mediated motility receptor (Intracellular hyaluronic acid-binding protein) (Receptor for hyaluronan-mediated motility) (CD antigen CD168) Rattus norvegicus (Rat) cell-cell signaling [GO:0007267]; cytoskeleton organization [GO:0007010]; endocytosis [GO:0006897]; hyaluronan catabolic process [GO:0030214]; receptor-mediated endocytosis [GO:0006898] GO:0005540; GO:0005737; GO:0005819; GO:0006897; GO:0006898; GO:0007010; GO:0007267; GO:0009986; GO:0030214; GO:0038024 23299 XM_029338774.2 195 260 55 109 77 NA NA NA NA NA NA 23300 XM_029336891.2 4 6 0 11 28 Q9IAK8 1.37e-88 T-box transcription factor TBX5-A (zftbx5a) (T-box protein 5) (zTbx5) Danio rerio (Zebrafish) (Brachydanio rerio) animal organ morphogenesis [GO:0009887]; atrial ventricular junction remodeling [GO:0003294]; atrioventricular canal development [GO:0036302]; atrioventricular valve formation [GO:0003190]; cardiac left ventricle formation [GO:0003218]; cardiac muscle cell differentiation [GO:0055007]; cardiac muscle tissue regeneration [GO:0061026]; cell fate specification [GO:0001708]; DNA-templated transcription [GO:0006351]; embryonic heart tube development [GO:0035050]; embryonic heart tube morphogenesis [GO:0003143]; embryonic pectoral fin morphogenesis [GO:0035118]; heart development [GO:0007507]; heart jogging [GO:0003146]; heart looping [GO:0001947]; heart morphogenesis [GO:0003007]; limb bud formation [GO:0060174]; optic nerve development [GO:0021554]; pattern specification process [GO:0007389]; pectoral fin development [GO:0033339]; pectoral fin morphogenesis [GO:0035138]; pericardium morphogenesis [GO:0003344]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proepicardium development [GO:0003342]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; retina morphogenesis in camera-type eye [GO:0060042] GO:0000978; GO:0000981; GO:0001708; GO:0001947; GO:0003007; GO:0003143; GO:0003146; GO:0003190; GO:0003218; GO:0003294; GO:0003342; GO:0003344; GO:0003700; GO:0005634; GO:0005737; GO:0006351; GO:0006355; GO:0006357; GO:0007389; GO:0007507; GO:0009887; GO:0015629; GO:0021554; GO:0032991; GO:0032993; GO:0033339; GO:0035050; GO:0035118; GO:0035138; GO:0036302; GO:0043565; GO:0045893; GO:0045944; GO:0055007; GO:0060042; GO:0060174; GO:0061026 23301 XR_006396290.1 0 78 113 66 9 NA NA NA NA NA NA 23302 XM_044309129.1 4 0 0 1 208 NA NA NA NA NA NA 23303 XM_044314488.1 2508 1723 1588 2734 2783 Q13459 0 Unconventional myosin-IXb (Unconventional myosin-9b) Homo sapiens (Human) actin filament-based movement [GO:0030048]; lamellipodium morphogenesis [GO:0072673]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385] GO:0000146; GO:0001726; GO:0003779; GO:0005096; GO:0005516; GO:0005524; GO:0005737; GO:0005829; GO:0005884; GO:0005938; GO:0007266; GO:0008270; GO:0015629; GO:0016020; GO:0016459; GO:0016887; GO:0030027; GO:0030048; GO:0031267; GO:0035023; GO:0035385; GO:0043008; GO:0043531; GO:0048471; GO:0048495; GO:0051015; GO:0051056; GO:0072673 23304 XM_044314488.1 2508 1723 1588 2734 2783 Q13459 2.26e-50 Unconventional myosin-IXb (Unconventional myosin-9b) Homo sapiens (Human) actin filament-based movement [GO:0030048]; lamellipodium morphogenesis [GO:0072673]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385] GO:0000146; GO:0001726; GO:0003779; GO:0005096; GO:0005516; GO:0005524; GO:0005737; GO:0005829; GO:0005884; GO:0005938; GO:0007266; GO:0008270; GO:0015629; GO:0016020; GO:0016459; GO:0016887; GO:0030027; GO:0030048; GO:0031267; GO:0035023; GO:0035385; GO:0043008; GO:0043531; GO:0048471; GO:0048495; GO:0051015; GO:0051056; GO:0072673 23305 XM_044324019.1 21 54 63 68 118 NA NA NA NA NA NA 23306 XM_029330324.2 2711 2455 1646 2407 2058 A1A4K8 1.23e-109 Splicing factor U2AF 35 kDa subunit (U2 auxiliary factor 35 kDa subunit) (U2 snRNP auxiliary factor small subunit) Bos taurus (Bovine) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0005681; GO:0016607; GO:0030628; GO:0046872; GO:0050733; GO:0071013; GO:0089701 23307 XM_044307568.1 324 307 269 221 338 P22027 6.5e-31 ATP synthase subunit s, mitochondrial (ATP synthase-coupling factor B) (FB) (Distal membrane arm assembly complex 2-like protein) (Mitochondrial ATP synthase regulatory component factor B) Bos taurus (Bovine) ATP biosynthetic process [GO:0006754]; proton transmembrane transport [GO:1902600] GO:0005737; GO:0005743; GO:0006754; GO:0045263; GO:0046872; GO:1902600 23308 XM_044326789.1 75 8 23 28 1 NA NA NA NA NA NA 23309 XR_006393701.1 450 338 501 266 976 NA NA NA NA NA NA 23310 XM_044326674.1 0 0 6 0 97 C5NSL2 1.38e-45 DELTA-actitoxin-Aas1a (DELTA-AITX-Aas1a) (Bandaporin) (Cytolysin bp-1) Anthopleura asiatica (Sea anemone) cation transport [GO:0006812]; cytolysis in another organism [GO:0051715]; pore complex assembly [GO:0046931] GO:0005576; GO:0006812; GO:0015267; GO:0042151; GO:0044218; GO:0046930; GO:0046931; GO:0051715; GO:0090729 23311 XM_044310610.1 0 349 498 0 0 P31836 3.51e-42 Neural cell adhesion molecule 1 (N-CAM-1) (NCAM-1) Bos taurus (Bovine) axon guidance [GO:0007411]; dendrite self-avoidance [GO:0070593]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005886; GO:0007156; GO:0007411; GO:0030424; GO:0070593; GO:0098632 23312 XM_029337395.2 1274 1015 581 1147 884 Q9BXW7 4.01e-91 Haloacid dehalogenase-like hydrolase domain-containing 5 (Cat eye syndrome critical region protein 5) Homo sapiens (Human) glycerophospholipid biosynthetic process [GO:0046474] GO:0005739; GO:0046474 23313 XM_044322594.1 0 0 0 16 16 NA NA NA NA NA NA 23314 XR_006396565.1 20 25 0 26 3 NA NA NA NA NA NA 23315 XM_044316668.1 0 0 42 133 0 Q923J1 6.26e-159 Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Channel-kinase 1) (Long transient receptor potential channel 7) (LTrpC-7) (LTrpC7) (Transient receptor potential-phospholipase C-interacting kinase) (TRP-PLIK) Mus musculus (Mouse) actomyosin structure organization [GO:0031032]; calcium ion transport [GO:0006816]; calcium-dependent cell-matrix adhesion [GO:0016340]; cation transmembrane transport [GO:0098655]; cellular magnesium ion homeostasis [GO:0010961]; divalent inorganic cation homeostasis [GO:0072507]; memory [GO:0007613]; necroptotic process [GO:0070266]; positive regulation of apoptotic process [GO:0043065]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein tetramerization [GO:0051262] GO:0001726; GO:0003779; GO:0004672; GO:0004674; GO:0005261; GO:0005262; GO:0005524; GO:0005737; GO:0005886; GO:0006468; GO:0006816; GO:0007613; GO:0010961; GO:0016020; GO:0016301; GO:0016340; GO:0017022; GO:0030672; GO:0031032; GO:0043005; GO:0043025; GO:0043065; GO:0043196; GO:0046777; GO:0046872; GO:0051262; GO:0070266; GO:0072507; GO:0098655; GO:0106310 23316 XM_044329195.1 0 0 6 92 20 NA NA NA NA NA NA 23317 XM_044327941.1 16 19 7 60 6 NA NA NA NA NA NA 23318 XM_029340740.2 23 12 9 9 110 Q96P56 3.11e-68 Cation channel sperm-associated protein 2 (CatSper2) Homo sapiens (Human) fertilization [GO:0009566]; flagellated sperm motility [GO:0030317]; regulation of ion transmembrane transport [GO:0034765]; sperm capacitation [GO:0048240] GO:0005227; GO:0005244; GO:0005262; GO:0005886; GO:0009566; GO:0030317; GO:0031514; GO:0034765; GO:0036128; GO:0048240 23319 XM_029327222.2 283 275 0 98 0 P47736 1.17e-113 Rap1 GTPase-activating protein 1 (Rap1GAP) (Rap1GAP1) Homo sapiens (Human) activation of GTPase activity [GO:0090630]; adaptive immune response [GO:0002250]; cellular response to glial cell derived neurotrophic factor [GO:1990792]; negative regulation of GTP binding [GO:1904425]; negative regulation of microvillus assembly [GO:1903697]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of thyroid gland epithelial cell proliferation [GO:1904442]; positive regulation of GTPase activity [GO:0043547]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] GO:0000139; GO:0002250; GO:0003924; GO:0005096; GO:0005737; GO:0005769; GO:0005829; GO:0007165; GO:0016020; GO:0030424; GO:0030425; GO:0031267; GO:0042803; GO:0043025; GO:0043087; GO:0043547; GO:0045665; GO:0051056; GO:0090630; GO:1903697; GO:1904425; GO:1904442; GO:1990792 23320 XM_029349714.2 8 33 36 29 76 NA NA NA NA NA NA 23321 XM_044322929.1 541 535 288 462 508 Q8N865 2.48e-31 Uncharacterized protein C7orf31 Homo sapiens (Human) NA GO:0005737; GO:0005813 23322 XM_044325345.1 2 1 12 3 23 P48733 8.39e-30 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Bos taurus (Bovine) antibacterial innate immune response [GO:0140367]; defense response to Gram-negative bacterium [GO:0050829] GO:0000922; GO:0005201; GO:0005509; GO:0005576; GO:0005929; GO:0016020; GO:0016323; GO:0016324; GO:0031012; GO:0050829; GO:0060170; GO:0140367 23323 XM_029356231.2 2435 1375 1302 2397 2106 P0C5Y8 1.23e-28 Alsin (Amyotrophic lateral sclerosis 2 protein homolog) Rattus norvegicus (Rat) axonogenesis [GO:0007409]; behavioral fear response [GO:0001662]; cell death [GO:0008219]; endosomal transport [GO:0016197]; endosome organization [GO:0007032]; in utero embryonic development [GO:0001701]; locomotory behavior [GO:0007626]; lysosomal transport [GO:0007041]; neuromuscular junction development [GO:0007528]; neuron projection morphogenesis [GO:0048812]; positive regulation of GTPase activity [GO:0043547]; positive regulation of protein kinase activity [GO:0045860]; protein homooligomerization [GO:0051260]; protein localization [GO:0008104]; Rac protein signal transduction [GO:0016601]; receptor recycling [GO:0001881]; regulation of endosome size [GO:0051036]; regulation of GTPase activity [GO:0043087]; response to oxidative stress [GO:0006979]; synaptic transmission, glutamatergic [GO:0035249]; vesicle organization [GO:0016050] GO:0001662; GO:0001701; GO:0001726; GO:0001881; GO:0005085; GO:0005096; GO:0005634; GO:0005737; GO:0005769; GO:0005813; GO:0005829; GO:0006979; GO:0007032; GO:0007041; GO:0007409; GO:0007528; GO:0007626; GO:0008104; GO:0008219; GO:0014069; GO:0016020; GO:0016050; GO:0016197; GO:0016601; GO:0030027; GO:0030424; GO:0030425; GO:0030426; GO:0031267; GO:0031982; GO:0032991; GO:0035249; GO:0042802; GO:0042803; GO:0043005; GO:0043025; GO:0043087; GO:0043197; GO:0043231; GO:0043539; GO:0043547; GO:0045202; GO:0045860; GO:0048812; GO:0051036; GO:0051260 23324 XM_029335958.2 30 81 124 79 158 F1LV46 1.23e-95 Indoleamine 2,3-dioxygenase 2 (IDO-2) (EC 1.13.11.-) (Indoleamine 2,3-dioxygenase-like protein 1) (Indoleamine-pyrrole 2,3-dioxygenase-like protein 1) Rattus norvegicus (Rat) 'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; immune system process [GO:0002376]; tryptophan catabolic process to kynurenine [GO:0019441] GO:0002376; GO:0004833; GO:0005737; GO:0019441; GO:0020037; GO:0033754; GO:0034354; GO:0046872 23325 XM_044313082.1 1313 47 10 139 67 NA NA NA NA NA NA 23326 XM_029344363.2 1168 112 308 258 821 Q5XJ85 6.53e-27 Myeloid differentiation primary response protein MyD88 Danio rerio (Zebrafish) (Brachydanio rerio) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; monocyte activation [GO:0042117]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; neutrophil activation involved in immune response [GO:0002283]; neutrophil chemotaxis [GO:0030593]; positive regulation of hematopoietic progenitor cell differentiation [GO:1901534]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of hematopoietic progenitor cell differentiation [GO:1901532]; response to molecule of bacterial origin [GO:0002237]; Toll signaling pathway [GO:0008063] GO:0002218; GO:0002237; GO:0002283; GO:0002755; GO:0005737; GO:0005886; GO:0006954; GO:0008063; GO:0030593; GO:0035325; GO:0042117; GO:0042742; GO:0043123; GO:0045087; GO:0050830; GO:0070976; GO:1901532; GO:1901534 23327 XM_044322864.1 457 0 85 205 408 NA NA NA NA NA NA 23328 XM_029345145.2 195 133 165 146 233 NA NA NA NA NA NA 23329 XM_044307578.1 643 456 226 450 150 Q497B8 5.64e-22 Bifunctional peptidase and arginyl-hydroxylase JMJD5 (EC 1.14.11.73) (EC 3.4.-.-) (JmjC domain-containing protein 5) (Jumonji C domain-containing protein 5) (L-arginine (3R)-hydroxylase KDM8) Rattus norvegicus (Rat) chromatin organization [GO:0006325]; circadian regulation of gene expression [GO:0032922]; G2/M transition of mitotic cell cycle [GO:0000086]; histone H3-K36 demethylation [GO:0070544]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of DNA-templated transcription [GO:0045893]; protein destabilization [GO:0031648]; proteolysis [GO:0006508] GO:0000086; GO:0003682; GO:0004175; GO:0004177; GO:0005634; GO:0005694; GO:0006325; GO:0006508; GO:0016706; GO:0031648; GO:0032922; GO:0035064; GO:0045892; GO:0045893; GO:0046872; GO:0051864; GO:0070544; GO:0106157 23330 XM_044321734.1 18 4 12 7 8 Q6JHU9 0 Histone lysine acetyltransferase CREBBP (EC 2.3.1.48) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-) Rattus norvegicus (Rat) behavioral response to cocaine [GO:0048148]; cell population proliferation [GO:0008283]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to UV [GO:0034644]; cellular response to virus [GO:0098586]; face morphogenesis [GO:0060325]; germ-line stem cell population maintenance [GO:0030718]; histone acetylation [GO:0016573]; histone glutamine methylation [GO:1990258]; histone modification [GO:0016570]; long-term memory [GO:0007616]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription by RNA polymerase I [GO:0016479]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral process [GO:0048525]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; regulation of DNA-templated transcription [GO:0006355]; response to interleukin-1 [GO:0070555]; response to ischemia [GO:0002931]; rhythmic process [GO:0048511] GO:0000122; GO:0000123; GO:0000785; GO:0000940; GO:0000977; GO:0001093; GO:0001223; GO:0002039; GO:0002931; GO:0003677; GO:0003682; GO:0003684; GO:0003713; GO:0003714; GO:0004402; GO:0005634; GO:0005654; GO:0005667; GO:0005737; GO:0006355; GO:0006473; GO:0007616; GO:0008140; GO:0008270; GO:0008283; GO:0010628; GO:0016407; GO:0016479; GO:0016570; GO:0016573; GO:0016604; GO:0018076; GO:0019904; GO:0030511; GO:0030718; GO:0031490; GO:0031648; GO:0032688; GO:0032793; GO:0032991; GO:0034644; GO:0035729; GO:0042975; GO:0043426; GO:0045893; GO:0045944; GO:0046332; GO:0048148; GO:0048511; GO:0048525; GO:0060090; GO:0060325; GO:0060355; GO:0060999; GO:0061629; GO:0061733; GO:0070555; GO:0090575; GO:0097718; GO:0098586; GO:0140297; GO:1900087; GO:1901224; GO:1990258 23331 XM_044321734.1 18 4 12 7 8 Q6JHU9 1.59e-71 Histone lysine acetyltransferase CREBBP (EC 2.3.1.48) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-) Rattus norvegicus (Rat) behavioral response to cocaine [GO:0048148]; cell population proliferation [GO:0008283]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to UV [GO:0034644]; cellular response to virus [GO:0098586]; face morphogenesis [GO:0060325]; germ-line stem cell population maintenance [GO:0030718]; histone acetylation [GO:0016573]; histone glutamine methylation [GO:1990258]; histone modification [GO:0016570]; long-term memory [GO:0007616]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription by RNA polymerase I [GO:0016479]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral process [GO:0048525]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; regulation of DNA-templated transcription [GO:0006355]; response to interleukin-1 [GO:0070555]; response to ischemia [GO:0002931]; rhythmic process [GO:0048511] GO:0000122; GO:0000123; GO:0000785; GO:0000940; GO:0000977; GO:0001093; GO:0001223; GO:0002039; GO:0002931; GO:0003677; GO:0003682; GO:0003684; GO:0003713; GO:0003714; GO:0004402; GO:0005634; GO:0005654; GO:0005667; GO:0005737; GO:0006355; GO:0006473; GO:0007616; GO:0008140; GO:0008270; GO:0008283; GO:0010628; GO:0016407; GO:0016479; GO:0016570; GO:0016573; GO:0016604; GO:0018076; GO:0019904; GO:0030511; GO:0030718; GO:0031490; GO:0031648; GO:0032688; GO:0032793; GO:0032991; GO:0034644; GO:0035729; GO:0042975; GO:0043426; GO:0045893; GO:0045944; GO:0046332; GO:0048148; GO:0048511; GO:0048525; GO:0060090; GO:0060325; GO:0060355; GO:0060999; GO:0061629; GO:0061733; GO:0070555; GO:0090575; GO:0097718; GO:0098586; GO:0140297; GO:1900087; GO:1901224; GO:1990258 23332 XR_003824136.2 0 0 0 9 13 NA NA NA NA NA NA 23333 XM_029327764.2 22 0 15 17 43 NA NA NA NA NA NA 23334 XM_029333238.2 171 205 15 289 0 Q571I4 2.17e-29 Inactive tyrosine-protein kinase PRAG1 (Notch activation complex kinase) (PEAK1-related kinase-activating pseudokinase 1) (Sugen kinase 223) (Tyrosine-protein kinase SgK223) Mus musculus (Mouse) cell migration [GO:0016477]; negative regulation of neuron projection development [GO:0010977]; positive regulation of Rho protein signal transduction [GO:0035025]; protein phosphorylation [GO:0006468]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of Notch signaling pathway [GO:0008593] GO:0004672; GO:0005634; GO:0005737; GO:0005925; GO:0006468; GO:0008360; GO:0008593; GO:0010977; GO:0016477; GO:0035025; GO:0042802; GO:2000145 23335 XM_044321487.1 15 3 1 0 6 Q01804 1.91e-71 OTU domain-containing protein 4 (EC 3.4.19.12) (HIV-1-induced protein HIN-1) Homo sapiens (Human) innate immune response [GO:0045087]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; positive regulation of DNA demethylation [GO:1901537]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; regulation of protein K48-linked deubiquitination [GO:1903093] GO:0003723; GO:0004843; GO:0005634; GO:0005829; GO:0016579; GO:0034122; GO:0045087; GO:0060090; GO:0061578; GO:0070536; GO:0071108; GO:1901537; GO:1903093; GO:2000660 23336 XR_006396333.1 23 7 59 11 115 NA NA NA NA NA NA 23337 XM_044316793.1 38 0 56 39 0 NA NA NA NA NA NA 23338 XR_006395218.1 17 34 18 25 81 NA NA NA NA NA NA 23339 XM_044321177.1 69 288 217 90 249 NA NA NA NA NA NA 23340 XM_044321702.1 53 0 64 50 0 B6CHA3 0 E3 ubiquitin-protein ligase UHRF1 (EC 2.3.2.27) (Nuclear zinc finger protein Np95) (XNp95) (RING-type E3 ubiquitin transferase UHRF1) (Ubiquitin-like PHD and RING finger domain-containing protein 1) (Ubiquitin-like-containing PHD and RING finger domains protein 1) Xenopus laevis (African clawed frog) cell cycle [GO:0007049]; chromatin organization [GO:0006325]; histone ubiquitination [GO:0016574]; maintenance of DNA methylation [GO:0010216]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein autoubiquitination [GO:0051865]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000122; GO:0000785; GO:0000791; GO:0000792; GO:0004842; GO:0005634; GO:0005657; GO:0006325; GO:0006511; GO:0007049; GO:0008270; GO:0010216; GO:0016574; GO:0035064; GO:0042393; GO:0044729; GO:0051865 23341 XM_044327805.1 40 0 0 0 39 NA NA NA NA NA NA 23342 XM_029341131.2 620 539 463 766 863 A6H7H1 1.62e-69 Constitutive coactivator of PPAR-gamma-like protein 1 (Oxidative stress-associated Src activator) (Protein FAM120A) Bos taurus (Bovine) NA GO:0003723; GO:0005737; GO:0005886 23343 XM_029341131.2 620 539 463 766 863 A6H7H1 1.31e-62 Constitutive coactivator of PPAR-gamma-like protein 1 (Oxidative stress-associated Src activator) (Protein FAM120A) Bos taurus (Bovine) NA GO:0003723; GO:0005737; GO:0005886 23344 XM_044315668.1 1 10 3 17 5 NA NA NA NA NA NA 23345 XM_044327516.1 103 126 74 57 199 NA NA NA NA NA NA 23346 XM_044313109.1 155 50 30 131 93 Q7RTR2 2.12e-47 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 23347 XM_044313109.1 155 50 30 131 93 Q7RTR2 1.26e-46 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 23348 XM_044313109.1 155 50 30 131 93 Q7RTR2 1.35e-46 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 23349 XM_044313109.1 155 50 30 131 93 Q7RTR2 9.06e-43 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 23350 XM_044313109.1 155 50 30 131 93 Q7RTR2 5.3e-42 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 23351 XM_044313109.1 155 50 30 131 93 Q7RTR2 9.39e-35 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 23352 XM_044323210.1 69 30 37 32 191 Q7RTR2 1.28e-36 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 23353 XM_044323210.1 69 30 37 32 191 Q7RTR2 9.32e-28 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 23354 XM_044323210.1 69 30 37 32 191 Q7RTR2 8.23e-27 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 23355 XM_044323210.1 69 30 37 32 191 Q7RTR2 1.48e-22 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 23356 XR_006397273.1 261 313 281 555 671 NA NA NA NA NA NA 23357 XM_044328027.1 868 1804 1206 639 366 NA NA NA NA NA NA 23358 XM_044317127.1 113 43 60 57 56 Q9Y3Q0 0 N-acetylated-alpha-linked acidic dipeptidase 2 (EC 3.4.17.21) (Glutamate carboxypeptidase III) (GCPIII) (N-acetylated-alpha-linked acidic dipeptidase II) (NAALADase II) Homo sapiens (Human) proteolysis [GO:0006508] GO:0004180; GO:0004181; GO:0005886; GO:0006508; GO:0008236; GO:0008239; GO:0016020; GO:0016805; GO:0046872 23359 XM_044306788.1 22 54 38 28 32 NA NA NA NA NA NA 23360 XM_044314908.1 1848 805 1313 934 2924 NA NA NA NA NA NA 23361 XM_029324648.2 5820 4943 4354 6411 3546 Q91YN5 4.36e-159 UDP-N-acetylhexosamine pyrophosphorylase [Includes: UDP-N-acetylgalactosamine pyrophosphorylase (EC 2.7.7.83); UDP-N-acetylglucosamine pyrophosphorylase (EC 2.7.7.23)] Mus musculus (Mouse) UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047] GO:0003977; GO:0005654; GO:0005829; GO:0005886; GO:0006047; GO:0006048; GO:0030246; GO:0042802; GO:0052630 23362 XR_006393066.1 41 2 25 5 151 NA NA NA NA NA NA 23363 XM_044315905.1 69 4 15 8 36 NA NA NA NA NA NA 23364 XM_029356523.2 502 413 336 281 492 Q5RE52 5.17e-122 Anaphase-promoting complex subunit 5 (APC5) (Cyclosome subunit 5) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cell cycle [GO:0007049]; cell division [GO:0051301]; protein K11-linked ubiquitination [GO:0070979] GO:0005634; GO:0005680; GO:0005737; GO:0005819; GO:0007049; GO:0019903; GO:0051301; GO:0070979 23365 XM_044322222.1 139 0 43 254 220 Q5F499 0 Dynamin-like 120 kDa protein, mitochondrial (EC 3.6.5.5) (Optic atrophy protein 1 homolog) [Cleaved into: Dynamin-like 120 kDa protein, form S1] Gallus gallus (Chicken) apoptotic process [GO:0006915]; GTP metabolic process [GO:0046039]; membrane tubulation [GO:0097749]; mitochondrial fusion [GO:0008053] GO:0003924; GO:0005525; GO:0005737; GO:0005743; GO:0005758; GO:0005874; GO:0006915; GO:0008017; GO:0008053; GO:0016020; GO:0031966; GO:0046039; GO:0070300; GO:0097749; GO:1901612 23366 XM_029335897.2 78 38 0 148 11 NA NA NA NA NA NA 23367 XM_029343787.2 450 219 148 355 513 Q9I8C7 2.2e-81 Neuronal acetylcholine receptor subunit alpha-10 (Alpha 10 nAChR) (Nicotinic acetylcholine receptor subunit alpha-10) (NACHR alpha-10) Gallus gallus (Chicken) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; response to auditory stimulus [GO:0010996]; signal transduction [GO:0007165] GO:0004888; GO:0005231; GO:0005262; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0010996; GO:0022848; GO:0030594; GO:0034220; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051899; GO:1904315 23368 XM_044309133.1 0 104 28 46 7 NA NA NA NA NA NA 23369 XM_044324363.1 6 0 3 9 9 O60290 2.33e-24 Zinc finger protein 862 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006355; GO:0046872; GO:0046983 23370 XM_029349111.2 735 544 301 607 316 Q3SZZ5 2.6e-41 Transmembrane protein 208 Bos taurus (Bovine) autophagy [GO:0006914]; vacuolar protein processing [GO:0006624] GO:0005773; GO:0005789; GO:0006624; GO:0006914 23371 XM_029346344.2 4933 1525 1549 3490 1966 B3EWY6 0 Skeletal aspartic acid-rich protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 23372 XM_029324632.2 528 455 417 527 246 Q10588 2.94e-47 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 (EC 3.2.2.6) (ADP-ribosyl cyclase 2) (Bone marrow stromal cell antigen 1) (BST-1) (Cyclic ADP-ribose hydrolase 2) (cADPr hydrolase 2) (CD antigen CD157) Homo sapiens (Human) humoral immune response [GO:0006959]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell population proliferation [GO:0008284]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium-mediated signaling [GO:0050848]; regulation of cell-matrix adhesion [GO:0001952]; regulation of cellular extravasation [GO:0002691]; regulation of inflammatory response [GO:0050727]; regulation of integrin-mediated signaling pathway [GO:2001044]; regulation of neutrophil chemotaxis [GO:0090022]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of superoxide metabolic process [GO:0090322]; signal transduction [GO:0007165] GO:0001931; GO:0001952; GO:0002691; GO:0003953; GO:0005576; GO:0005886; GO:0006959; GO:0007165; GO:0008284; GO:0016740; GO:0016849; GO:0019898; GO:0030890; GO:0032956; GO:0035579; GO:0050135; GO:0050727; GO:0050730; GO:0050848; GO:0061809; GO:0061811; GO:0061812; GO:0070062; GO:0090022; GO:0090322; GO:2001044 23373 XM_029334165.2 171 146 158 222 288 NA NA NA NA NA NA 23374 XM_029349486.2 658 300 177 331 176 Q90Z12 6.19e-42 Transcription factor HES-4-A (Hairy and enhancer of split 4-A) (Protein hairy-2) (Xhairy2) (Protein hairy-2a) (Xhairy2a) Xenopus laevis (African clawed frog) BMP signaling pathway [GO:0030509]; floor plate development [GO:0033504]; lens development in camera-type eye [GO:0002088]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural crest formation [GO:0014029]; prechordal plate formation [GO:0021501] GO:0000122; GO:0002088; GO:0005634; GO:0014029; GO:0021501; GO:0030509; GO:0033504; GO:0043066; GO:0043425; GO:0043565; GO:0045892; GO:0046983 23375 XM_029324809.2 22 0 237 239 0 NA NA NA NA NA NA 23376 XR_006397922.1 102 60 54 77 90 NA NA NA NA NA NA 23377 XM_029355469.2 14806 14756 10196 12639 11514 Q5RC11 3.35e-106 60S ribosomal protein L11 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; positive regulation of signal transduction by p53 class mediator [GO:1901798]; protein localization to nucleus [GO:0034504]; translation [GO:0006412] GO:0003735; GO:0005654; GO:0005730; GO:0005737; GO:0005840; GO:0006412; GO:0019843; GO:0032435; GO:0034504; GO:1901798; GO:1990904 23378 XM_044308498.1 631 590 257 504 278 NA NA NA NA NA NA 23379 XM_044307110.1 4 65 8 63 10 Q9U6Y6 8.19e-109 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 23380 XM_029326989.2 325 369 171 330 452 Q8BYI6 3.9e-95 Lysophosphatidylcholine acyltransferase 2 (LPC acyltransferase 2) (LPCAT-2) (LysoPC acyltransferase 2) (EC 2.3.1.23) (1-acylglycerol-3-phosphate O-acyltransferase 11) (1-AGP acyltransferase 11) (1-AGPAT 11) (EC 2.3.1.51) (1-acylglycerophosphocholine O-acyltransferase) (1-alkenylglycerophosphocholine O-acyltransferase) (EC 2.3.1.25) (1-alkylglycerophosphocholine O-acetyltransferase) (EC 2.3.1.67) (Acetyl-CoA:lyso-platelet-activating factor acetyltransferase) (Acetyl-CoA:lyso-PAF acetyltransferase) (Lyso-PAF acetyltransferase) (LysoPAFAT) (Acyltransferase-like 1) Mus musculus (Mouse) membrane organization [GO:0061024]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; platelet activating factor biosynthetic process [GO:0006663] GO:0000139; GO:0003841; GO:0005509; GO:0005783; GO:0005789; GO:0005795; GO:0005811; GO:0005886; GO:0006663; GO:0016020; GO:0036151; GO:0047159; GO:0047184; GO:0047192; GO:0050200; GO:0061024 23381 XM_029334845.2 44 28 0 33 0 NA NA NA NA NA NA 23382 XM_044307149.1 72 126 200 201 453 NA NA NA NA NA NA 23383 XM_044309137.1 99 697 726 902 545 NA NA NA NA NA NA 23384 XM_044315727.1 20 33 5 21 9 NA NA NA NA NA NA 23385 XM_044324890.1 0 0 0 18 0 Q8K4M9 0 Oxysterol-binding protein-related protein 1 (ORP-1) (OSBP-related protein 1) Rattus norvegicus (Rat) NA GO:0005768; GO:0005770; GO:0005829; GO:0015248; GO:0015485; GO:0016020; GO:0032934; GO:0043231; GO:0044232 23386 XM_044321733.1 407 620 606 172 505 Q6JHU9 0 Histone lysine acetyltransferase CREBBP (EC 2.3.1.48) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-) Rattus norvegicus (Rat) behavioral response to cocaine [GO:0048148]; cell population proliferation [GO:0008283]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to UV [GO:0034644]; cellular response to virus [GO:0098586]; face morphogenesis [GO:0060325]; germ-line stem cell population maintenance [GO:0030718]; histone acetylation [GO:0016573]; histone glutamine methylation [GO:1990258]; histone modification [GO:0016570]; long-term memory [GO:0007616]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription by RNA polymerase I [GO:0016479]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral process [GO:0048525]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; regulation of DNA-templated transcription [GO:0006355]; response to interleukin-1 [GO:0070555]; response to ischemia [GO:0002931]; rhythmic process [GO:0048511] GO:0000122; GO:0000123; GO:0000785; GO:0000940; GO:0000977; GO:0001093; GO:0001223; GO:0002039; GO:0002931; GO:0003677; GO:0003682; GO:0003684; GO:0003713; GO:0003714; GO:0004402; GO:0005634; GO:0005654; GO:0005667; GO:0005737; GO:0006355; GO:0006473; GO:0007616; GO:0008140; GO:0008270; GO:0008283; GO:0010628; GO:0016407; GO:0016479; GO:0016570; GO:0016573; GO:0016604; GO:0018076; GO:0019904; GO:0030511; GO:0030718; GO:0031490; GO:0031648; GO:0032688; GO:0032793; GO:0032991; GO:0034644; GO:0035729; GO:0042975; GO:0043426; GO:0045893; GO:0045944; GO:0046332; GO:0048148; GO:0048511; GO:0048525; GO:0060090; GO:0060325; GO:0060355; GO:0060999; GO:0061629; GO:0061733; GO:0070555; GO:0090575; GO:0097718; GO:0098586; GO:0140297; GO:1900087; GO:1901224; GO:1990258 23387 XM_044321733.1 407 620 606 172 505 Q6JHU9 2.46e-71 Histone lysine acetyltransferase CREBBP (EC 2.3.1.48) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-) Rattus norvegicus (Rat) behavioral response to cocaine [GO:0048148]; cell population proliferation [GO:0008283]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to UV [GO:0034644]; cellular response to virus [GO:0098586]; face morphogenesis [GO:0060325]; germ-line stem cell population maintenance [GO:0030718]; histone acetylation [GO:0016573]; histone glutamine methylation [GO:1990258]; histone modification [GO:0016570]; long-term memory [GO:0007616]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription by RNA polymerase I [GO:0016479]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral process [GO:0048525]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; regulation of DNA-templated transcription [GO:0006355]; response to interleukin-1 [GO:0070555]; response to ischemia [GO:0002931]; rhythmic process [GO:0048511] GO:0000122; GO:0000123; GO:0000785; GO:0000940; GO:0000977; GO:0001093; GO:0001223; GO:0002039; GO:0002931; GO:0003677; GO:0003682; GO:0003684; GO:0003713; GO:0003714; GO:0004402; GO:0005634; GO:0005654; GO:0005667; GO:0005737; GO:0006355; GO:0006473; GO:0007616; GO:0008140; GO:0008270; GO:0008283; GO:0010628; GO:0016407; GO:0016479; GO:0016570; GO:0016573; GO:0016604; GO:0018076; GO:0019904; GO:0030511; GO:0030718; GO:0031490; GO:0031648; GO:0032688; GO:0032793; GO:0032991; GO:0034644; GO:0035729; GO:0042975; GO:0043426; GO:0045893; GO:0045944; GO:0046332; GO:0048148; GO:0048511; GO:0048525; GO:0060090; GO:0060325; GO:0060355; GO:0060999; GO:0061629; GO:0061733; GO:0070555; GO:0090575; GO:0097718; GO:0098586; GO:0140297; GO:1900087; GO:1901224; GO:1990258 23388 XM_044318962.1 0 0 0 36 0 NA NA NA NA NA NA 23389 XM_029358336.2 156 113 143 144 215 Q9NRX2 2.62e-22 39S ribosomal protein L17, mitochondrial (L17mt) (MRP-L17) (LYST-interacting protein 2) (Mitochondrial large ribosomal subunit protein bL17m) Homo sapiens (Human) mitochondrial translation [GO:0032543] GO:0003735; GO:0005739; GO:0005743; GO:0005762; GO:0015934; GO:0019904; GO:0032543 23390 XM_029339837.2 264 262 147 265 210 P14198 7.63e-31 AAC-rich mRNA clone AAC4 protein Dictyostelium discoideum (Social amoeba) NA GO:0016020 23391 XM_029346387.2 401 173 175 628 203 Q58EX7 7.27e-140 Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (PH domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1) Homo sapiens (Human) regulation of small GTPase mediated signal transduction [GO:0051056] GO:0005085; GO:0005829; GO:0051056 23392 XM_044327256.1 839 244 713 1481 2097 Q3UZV7 7.24e-30 Endosome/lysosome-associated apoptosis and autophagy regulator family member 2 (Estrogen-induced gene 121-like protein) Mus musculus (Mouse) negative regulation of nervous system development [GO:0051961]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of epidermis development [GO:0045684] GO:0005886; GO:0016020; GO:0030513; GO:0045684; GO:0051961; GO:0070700 23393 XM_029336621.2 534 519 261 323 237 Q8C5L6 2.14e-69 Inositol polyphosphate 5-phosphatase K (EC 3.1.3.56) (Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase) (EC 3.1.3.86) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (EC 3.1.3.36) (Skeletal muscle and kidney-enriched inositol phosphatase) Mus musculus (Mouse) cellular response to cAMP [GO:0071320]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to hormone stimulus [GO:0032870]; cellular response to insulin stimulus [GO:0032869]; cellular response to tumor necrosis factor [GO:0071356]; dephosphorylation [GO:0016311]; G protein-coupled receptor signaling pathway [GO:0007186]; glucose homeostasis [GO:0042593]; in utero embryonic development [GO:0001701]; inositol phosphate dephosphorylation [GO:0046855]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of dephosphorylation [GO:0035305]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of glycogen (starch) synthase activity [GO:2000466]; negative regulation of glycogen biosynthetic process [GO:0045719]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein targeting to membrane [GO:0090315]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of stress fiber assembly [GO:0051497]; phosphatidylinositol dephosphorylation [GO:0046856]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of renal water transport [GO:2001153]; positive regulation of urine volume [GO:0035810]; protein localization to plasma membrane [GO:0072659]; regulation of glycogen biosynthetic process [GO:0005979]; response to insulin [GO:0032868]; ruffle assembly [GO:0097178] GO:0001701; GO:0001726; GO:0001933; GO:0004439; GO:0004445; GO:0005000; GO:0005634; GO:0005737; GO:0005783; GO:0005802; GO:0005829; GO:0005886; GO:0005979; GO:0006469; GO:0007186; GO:0010801; GO:0010829; GO:0016020; GO:0016311; GO:0016312; GO:0032587; GO:0032868; GO:0032869; GO:0032870; GO:0033137; GO:0034485; GO:0034594; GO:0034595; GO:0035305; GO:0035810; GO:0042593; GO:0043005; GO:0043407; GO:0043922; GO:0045719; GO:0045869; GO:0045892; GO:0045893; GO:0046030; GO:0046627; GO:0046855; GO:0046856; GO:0048471; GO:0051497; GO:0051898; GO:0051926; GO:0052658; GO:0052659; GO:0071320; GO:0071356; GO:0071364; GO:0072659; GO:0090315; GO:0097178; GO:2000466; GO:2001153 23394 XR_006396409.1 387 235 195 209 190 NA NA NA NA NA NA 23395 XR_006392528.1 2 74 53 30 9 NA NA NA NA NA NA 23396 XM_029336469.2 531 235 243 318 395 NA NA NA NA NA NA 23397 XM_029344245.2 639 1017 346 41 37 Q7L1S5 8.69e-41 Carbohydrate sulfotransferase 9 (EC 2.8.2.-) (GalNAc-4-O-sulfotransferase 2) (GalNAc-4-ST2) (GalNAc4ST-2) (N-acetylgalactosamine-4-O-sulfotransferase 2) Homo sapiens (Human) carbohydrate biosynthetic process [GO:0016051]; chondroitin sulfate biosynthetic process [GO:0030206]; glycosaminoglycan metabolic process [GO:0030203]; hormone biosynthetic process [GO:0042446]; proteoglycan biosynthetic process [GO:0030166]; sulfur compound metabolic process [GO:0006790] GO:0000139; GO:0001537; GO:0005576; GO:0006790; GO:0008146; GO:0016020; GO:0016051; GO:0030166; GO:0030203; GO:0030206; GO:0042446; GO:0047756 23398 XM_044316947.1 124 140 49 189 155 Q5RGE6 1.51e-131 Heat shock 70 kDa protein 14 Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein refolding [GO:0042026]; vesicle-mediated transport [GO:0016192] GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0016192; GO:0016887; GO:0031072; GO:0034620; GO:0042026; GO:0044183; GO:0051082; GO:0051085; GO:0051787; GO:0140662 23399 XM_044327128.1 224 210 134 146 255 NA NA NA NA NA NA 23400 XR_006398090.1 24 85 73 185 156 NA NA NA NA NA NA 23401 XR_006392596.1 0 0 3 1 9 NA NA NA NA NA NA 23402 XM_029354468.2 5 0 12 0 13 NA NA NA NA NA NA 23403 XM_029356118.2 0 0 0 0 49 Q5TC82 6.95e-173 Roquin-1 (Roquin) (EC 2.3.2.27) (RING finger and C3H zinc finger protein 1) (RING finger and CCCH-type zinc finger domain-containing protein 1) (RING finger protein 198) Homo sapiens (Human) 3'-UTR-mediated mRNA destabilization [GO:0061158]; B cell homeostasis [GO:0001782]; cellular response to interleukin-1 [GO:0071347]; lymph node development [GO:0048535]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of germinal center formation [GO:0002635]; negative regulation of T-helper 17 cell differentiation [GO:2000320]; negative regulation of T-helper cell differentiation [GO:0045623]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; P-body assembly [GO:0033962]; positive regulation of mRNA catabolic process [GO:0061014]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; post-transcriptional regulation of gene expression [GO:0010608]; protein polyubiquitination [GO:0000209]; regulation of germinal center formation [GO:0002634]; regulation of miRNA metabolic process [GO:2000628]; regulation of mRNA stability [GO:0043488]; regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900151]; regulation of T cell receptor signaling pathway [GO:0050856]; spleen development [GO:0048536]; T cell homeostasis [GO:0043029]; T cell proliferation [GO:0042098]; T cell receptor signaling pathway [GO:0050852]; T follicular helper cell differentiation [GO:0061470]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000209; GO:0000288; GO:0000932; GO:0000956; GO:0001782; GO:0002634; GO:0002635; GO:0003723; GO:0003725; GO:0003729; GO:0003730; GO:0004842; GO:0006511; GO:0008270; GO:0010494; GO:0010608; GO:0030889; GO:0033962; GO:0035198; GO:0035613; GO:0042098; GO:0043029; GO:0043488; GO:0045623; GO:0046007; GO:0048535; GO:0048536; GO:0050852; GO:0050856; GO:0061014; GO:0061158; GO:0061470; GO:0061630; GO:0071347; GO:1900151; GO:1901224; GO:1905762; GO:2000320; GO:2000628 23404 XM_044326532.1 89 261 79 153 250 Q49UX2 7.37e-176 Dihydroxy-acid dehydratase 2 (DAD 2) (EC 4.2.1.9) Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229 / NCIMB 8711 / NCTC 7292 / S-41) isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099] GO:0000287; GO:0004160; GO:0009097; GO:0009099; GO:0051537 23405 XM_029354485.2 232 231 99 304 280 Q6DCP1 1.53e-115 FAD-dependent oxidoreductase domain-containing protein 1 (EC 1.-.-.-) Xenopus laevis (African clawed frog) mitochondrial respiratory chain complex I assembly [GO:0032981] GO:0005743; GO:0005747; GO:0016491; GO:0032981 23406 XM_029351847.2 5992 6946 4074 8633 7346 Q6FIF0 9.82e-44 AN1-type zinc finger protein 6 (Associated with PRK1 protein) (Zinc finger A20 domain-containing protein 3) Homo sapiens (Human) apoptotic process [GO:0006915]; cellular response to tumor necrosis factor [GO:0071356]; negative regulation of apoptotic process [GO:0043066]; protein targeting to peroxisome [GO:0006625]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122] GO:0003677; GO:0005829; GO:0006625; GO:0006915; GO:0008270; GO:0031593; GO:0043066; GO:0043122; GO:0071356 23407 XM_029356449.2 0 0 8 0 5 E2JA28 7.66e-39 Dapdiamide synthesis protein DdaC (EC 1.-.-.-) Enterobacter agglomerans (Erwinia herbicola) (Pantoea agglomerans) antibiotic biosynthetic process [GO:0017000] GO:0016491; GO:0017000 23408 XM_044323645.1 0 9 0 0 0 NA NA NA NA NA NA 23409 XM_029338181.2 0 3 0 20 67 Q7TS68 1.54e-130 tRNA (cytosine(72)-C(5))-methyltransferase NSUN6 (EC 2.1.1.-) (NOL1/NOP2/Sun domain family member 6) Mus musculus (Mouse) RNA methylation [GO:0001510]; tRNA C5-cytosine methylation [GO:0002946]; tRNA methylation [GO:0030488] GO:0000049; GO:0001510; GO:0002946; GO:0005654; GO:0005737; GO:0016428; GO:0030488 23410 XM_029344441.2 28 30 23 35 23 P30937 2.23e-21 Somatostatin receptor type 4 (SS-4-R) (SS4-R) (SS4R) Rattus norvegicus (Rat) cell migration [GO:0016477]; cellular response to glucocorticoid stimulus [GO:0071385]; forebrain development [GO:0030900]; negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0106072]; neuropeptide signaling pathway [GO:0007218]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0004930; GO:0004994; GO:0005737; GO:0005886; GO:0007218; GO:0016477; GO:0030900; GO:0042277; GO:0042923; GO:0043005; GO:0070374; GO:0071385; GO:0090238; GO:0106072 23411 XM_044317552.1 296 241 148 187 145 NA NA NA NA NA NA 23412 XM_044324422.1 111 72 142 103 129 P18460 7.64e-84 Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (Tyrosine kinase receptor CEK2) Gallus gallus (Chicken) apoptotic process [GO:0006915]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0004714; GO:0005007; GO:0005524; GO:0005886; GO:0006915; GO:0007169; GO:0008284; GO:0017134; GO:0033674; GO:0043235; GO:0043410 23413 XM_044328546.1 147 319 145 324 167 NA NA NA NA NA NA 23414 XM_044326584.1 7 191 27 274 55 Q80TR8 0 DDB1- and CUL4-associated factor 1 (Serine/threonine-protein kinase VPRBP) (EC 2.7.11.1) Mus musculus (Mouse) B cell differentiation [GO:0030183]; cell competition in a multicellular organism [GO:0035212]; chromatin organization [GO:0006325]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phosphorylation [GO:0016310]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; V(D)J recombination [GO:0033151] GO:0000122; GO:0001650; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0006325; GO:0008180; GO:0016310; GO:0016567; GO:0030183; GO:0030331; GO:0033151; GO:0035212; GO:0043687; GO:0080008; GO:0106310; GO:1990244 23415 XM_044326584.1 7 191 27 274 55 Q80TR8 9.57e-117 DDB1- and CUL4-associated factor 1 (Serine/threonine-protein kinase VPRBP) (EC 2.7.11.1) Mus musculus (Mouse) B cell differentiation [GO:0030183]; cell competition in a multicellular organism [GO:0035212]; chromatin organization [GO:0006325]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phosphorylation [GO:0016310]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; V(D)J recombination [GO:0033151] GO:0000122; GO:0001650; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0006325; GO:0008180; GO:0016310; GO:0016567; GO:0030183; GO:0030331; GO:0033151; GO:0035212; GO:0043687; GO:0080008; GO:0106310; GO:1990244 23416 XM_044328959.1 12 0 13 0 0 NA NA NA NA NA NA 23417 XM_029344063.2 3500 1307 609 908 949 Q5U2N8 0 Intraflagellar transport protein 56 (Tetratricopeptide repeat protein 26) (TPR repeat protein 26) Rattus norvegicus (Rat) axoneme assembly [GO:0035082]; cilium assembly [GO:0060271]; intraciliary anterograde transport [GO:0035720]; intraciliary transport [GO:0042073]; intraciliary transport involved in cilium assembly [GO:0035735]; manchette assembly [GO:1905198]; protein localization to cilium [GO:0061512]; protein transport [GO:0015031]; smoothened signaling pathway [GO:0007224]; spermatid development [GO:0007286] GO:0005813; GO:0005929; GO:0007224; GO:0007286; GO:0015031; GO:0030992; GO:0035082; GO:0035720; GO:0035735; GO:0036064; GO:0042073; GO:0043005; GO:0060271; GO:0061512; GO:0097546; GO:0120170; GO:1905198 23418 XM_029336565.2 612 340 410 679 906 E9Q8T7 9.63e-75 Dynein axonemal heavy chain 1 (Axonemal beta dynein heavy chain 1) (Ciliary dynein heavy chain 1) (mDHC7) Mus musculus (Mouse) cilium movement [GO:0003341]; cilium movement involved in cell motility [GO:0060294]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; flagellated sperm motility [GO:0030317]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018]; sperm axoneme assembly [GO:0007288] GO:0003341; GO:0003351; GO:0003777; GO:0005524; GO:0005576; GO:0005874; GO:0005930; GO:0007018; GO:0007288; GO:0008569; GO:0030286; GO:0030317; GO:0036126; GO:0036156; GO:0036159; GO:0045505; GO:0051959; GO:0060294 23419 XM_029336565.2 612 340 410 679 906 E9Q8T7 4.87e-50 Dynein axonemal heavy chain 1 (Axonemal beta dynein heavy chain 1) (Ciliary dynein heavy chain 1) (mDHC7) Mus musculus (Mouse) cilium movement [GO:0003341]; cilium movement involved in cell motility [GO:0060294]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; flagellated sperm motility [GO:0030317]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018]; sperm axoneme assembly [GO:0007288] GO:0003341; GO:0003351; GO:0003777; GO:0005524; GO:0005576; GO:0005874; GO:0005930; GO:0007018; GO:0007288; GO:0008569; GO:0030286; GO:0030317; GO:0036126; GO:0036156; GO:0036159; GO:0045505; GO:0051959; GO:0060294 23420 XM_029336565.2 612 340 410 679 906 E9Q8T7 4e-34 Dynein axonemal heavy chain 1 (Axonemal beta dynein heavy chain 1) (Ciliary dynein heavy chain 1) (mDHC7) Mus musculus (Mouse) cilium movement [GO:0003341]; cilium movement involved in cell motility [GO:0060294]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; flagellated sperm motility [GO:0030317]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018]; sperm axoneme assembly [GO:0007288] GO:0003341; GO:0003351; GO:0003777; GO:0005524; GO:0005576; GO:0005874; GO:0005930; GO:0007018; GO:0007288; GO:0008569; GO:0030286; GO:0030317; GO:0036126; GO:0036156; GO:0036159; GO:0045505; GO:0051959; GO:0060294 23421 XR_006392343.1 9 148 123 135 80 P0C0R5 5.75e-80 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) Rattus norvegicus (Rat) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006623; GO:0010506; GO:0015630; GO:0016236; GO:0016241; GO:0030242; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 23422 XM_029334130.2 0 0 0 0 127 NA NA NA NA NA NA 23423 XM_029328729.2 379 621 428 282 225 NA NA NA NA NA NA 23424 XM_044320079.1 45 100 209 78 72 B8EIZ7 2.13e-148 NA NA NA NA 23425 XM_029341025.2 8007 7466 4596 6152 3158 Q8NBX0 1.82e-136 Saccharopine dehydrogenase-like oxidoreductase (EC 1.-.-.-) Homo sapiens (Human) glycolipid biosynthetic process [GO:0009247] GO:0005576; GO:0005634; GO:0005739; GO:0005811; GO:0009247; GO:0016020; GO:0016491; GO:0030496; GO:0031093 23426 XM_044309059.1 531 14 18 5 8 NA NA NA NA NA NA 23427 XM_044319772.1 12 19 0 0 0 NA NA NA NA NA NA 23428 XM_029337861.2 449 330 312 197 755 Q6NSI8 3.2e-132 SANT and BTB domain regulator of class switch recombination (SANT and BTB domain regulator of CSR) Homo sapiens (Human) isotype switching [GO:0045190] GO:0042802; GO:0045190 23429 XM_029323673.2 532 314 196 141 118 NA NA NA NA NA NA 23430 XR_006391465.1 0 10 2 8 27 NA NA NA NA NA NA 23431 XM_029345158.2 761 727 332 1031 535 NA NA NA NA NA NA 23432 XM_029336038.2 190 398 216 291 183 NA NA NA NA NA NA 23433 XM_044317046.1 0 9 8 13 5 NA NA NA NA NA NA 23434 XM_029339124.2 5982 5769 1756 3093 2559 Q7ZVB1 1.46e-78 Charged multivesicular body protein 1b (Chromatin-modifying protein 1b) (CHMP1b) Danio rerio (Zebrafish) (Brachydanio rerio) endosome transport via multivesicular body sorting pathway [GO:0032509]; late endosome to vacuole transport [GO:0045324]; protein transport [GO:0015031] GO:0000815; GO:0005771; GO:0005829; GO:0015031; GO:0031902; GO:0032509; GO:0045324 23435 XM_044327304.1 15 17 0 71 6 NA NA NA NA NA NA 23436 XM_029345980.2 100 192 79 81 168 O55230 4.55e-70 DNA repair protein RAD51 homolog 4 (R51H3) (RAD51 homolog D) (RAD51-like protein 3) Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; chromosome organization [GO:0051276]; double-strand break repair via homologous recombination [GO:0000724]; interstrand cross-link repair [GO:0036297]; reciprocal meiotic recombination [GO:0007131]; regulation of cell cycle [GO:0051726]; strand invasion [GO:0042148]; telomere maintenance [GO:0000723]; telomere maintenance via recombination [GO:0000722] GO:0000400; GO:0000722; GO:0000723; GO:0000724; GO:0000781; GO:0003697; GO:0005524; GO:0005657; GO:0005813; GO:0006974; GO:0007131; GO:0008094; GO:0033063; GO:0036297; GO:0042148; GO:0043015; GO:0051276; GO:0051726; GO:0140664 23437 XM_029352109.2 1561 1456 748 1558 1218 A8MV24 3.8e-37 Uncharacterized protein C17orf98 Homo sapiens (Human) NA NA 23438 XM_029337109.2 1515 1041 892 1550 991 A2RV80 5.65e-70 GRAM domain-containing protein 4 Xenopus laevis (African clawed frog) apoptotic process [GO:0006915] GO:0005789; GO:0006915; GO:0031966 23439 XM_029334626.2 13 31 0 112 126 NA NA NA NA NA NA 23440 XM_044324998.1 50 10 16 20 1 Q96AY4 1.35e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23441 XM_044324998.1 50 10 16 20 1 Q96AY4 7.35e-56 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23442 XM_044324998.1 50 10 16 20 1 Q96AY4 8.03e-54 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23443 XM_044324998.1 50 10 16 20 1 Q96AY4 1.7e-52 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23444 XM_044324998.1 50 10 16 20 1 Q96AY4 3.53e-52 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23445 XM_044324998.1 50 10 16 20 1 Q96AY4 1.15e-47 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23446 XM_044324998.1 50 10 16 20 1 Q96AY4 1.34e-47 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23447 XM_044324998.1 50 10 16 20 1 Q96AY4 4.97e-47 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23448 XM_044324998.1 50 10 16 20 1 Q96AY4 1.81e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23449 XM_044324998.1 50 10 16 20 1 Q96AY4 1.29e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23450 XM_044324998.1 50 10 16 20 1 Q96AY4 2.01e-37 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23451 XM_044324998.1 50 10 16 20 1 Q96AY4 2.59e-37 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23452 XM_044324998.1 50 10 16 20 1 Q96AY4 5.36e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23453 XM_044324998.1 50 10 16 20 1 Q96AY4 1.65e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23454 XM_044324998.1 50 10 16 20 1 Q96AY4 1.09e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23455 XR_006395033.1 169 64 26 78 206 NA NA NA NA NA NA 23456 XM_044307611.1 262 0 1 0 0 NA NA NA NA NA NA 23457 XR_006395109.1 88 97 162 47 223 NA NA NA NA NA NA 23458 XM_029346561.2 365 118 205 393 466 NA NA NA NA NA NA 23459 XM_029345391.2 57 27 39 35 21 NA NA NA NA NA NA 23460 XM_029342705.2 819 760 330 699 595 Q03958 4.42e-30 Prefoldin subunit 6 (Protein Ke2) Mus musculus (Mouse) chaperone-mediated protein complex assembly [GO:0051131]; negative regulation of amyloid fibril formation [GO:1905907]; protein folding [GO:0006457] GO:0001540; GO:0005737; GO:0006457; GO:0016272; GO:0051082; GO:0051087; GO:0051131; GO:1905907; GO:1990062 23461 XM_029358220.2 351 317 228 246 309 Q8CHX6 1.46e-115 Membrane-bound transcription factor site-2 protease (EC 3.4.24.85) (Endopeptidase S2P) Mus musculus (Mouse) bone maturation [GO:0070977]; cholesterol metabolic process [GO:0008203]; membrane protein intracellular domain proteolysis [GO:0031293]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; regulation of response to endoplasmic reticulum stress [GO:1905897] GO:0000139; GO:0004222; GO:0005737; GO:0005789; GO:0008203; GO:0031293; GO:0046872; GO:0051091; GO:0070977; GO:1905897; GO:1990440 23462 XM_044323307.1 10 0 0 0 3 NA NA NA NA NA NA 23463 XM_029339858.2 0 2 10 0 10 NA NA NA NA NA NA 23464 XM_029338740.2 1448 1124 982 1269 1386 Q92968 2.72e-74 Peroxisomal membrane protein PEX13 (Peroxin-13) Homo sapiens (Human) cerebral cortex cell migration [GO:0021795]; fatty acid alpha-oxidation [GO:0001561]; locomotory behavior [GO:0007626]; microtubule-based peroxisome localization [GO:0060152]; neuron migration [GO:0001764]; protein import into peroxisome matrix, docking [GO:0016560]; suckling behavior [GO:0001967] GO:0001561; GO:0001764; GO:0001967; GO:0005777; GO:0005778; GO:0005829; GO:0007626; GO:0008320; GO:0016020; GO:0016560; GO:0021795; GO:0060152; GO:1990429 23465 XM_044324519.1 0 60 0 2 17 NA NA NA NA NA NA 23466 XM_044325869.1 2562 1005 1514 1644 1631 NA NA NA NA NA NA 23467 XM_029327279.2 2478 2846 2547 3065 2827 Q6TUG0 1.64e-150 DnaJ homolog subfamily B member 11 (ER-associated DNAJ) (ER-associated Hsp40 co-chaperone) (Endoplasmic reticulum DNA J domain-containing protein 3) (ER-resident protein ERdj3) (ERdj3) (ERj3p) (Liver regeneration-related protein LRRGT00084) Rattus norvegicus (Rat) mRNA modification [GO:0016556]; negative regulation of neurogenesis [GO:0050768]; positive regulation of ATP-dependent activity [GO:0032781]; protein folding [GO:0006457]; protein maturation [GO:0051604] GO:0005102; GO:0005615; GO:0005634; GO:0005737; GO:0005783; GO:0005788; GO:0006457; GO:0016556; GO:0032781; GO:0034663; GO:0050768; GO:0051082; GO:0051604; GO:0051787; GO:0101031 23468 XM_029333570.2 6878 5795 3409 6735 7206 Q6XHI1 1.9e-27 Thioredoxin-2 (Trx-2) Drosophila yakuba (Fruit fly) cell redox homeostasis [GO:0045454]; defense response to fungus [GO:0050832]; determination of adult lifespan [GO:0008340]; response to oxidative stress [GO:0006979] GO:0005634; GO:0006979; GO:0008340; GO:0015035; GO:0045454; GO:0050832 23469 XM_044325426.1 217 77 157 157 157 NA NA NA NA NA NA 23470 XM_029332988.2 392 221 165 278 268 Q9CQR5 1.46e-28 Zinc finger matrin-type protein 5 (U11/U12 small nuclear ribonucleoprotein 20 kDa protein) (U11/U12 snRNP 20 kDa protein) Mus musculus (Mouse) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0005654; GO:0005689; GO:0006397; GO:0008270; GO:0008380 23471 XR_006392725.1 47 38 5 26 40 NA NA NA NA NA NA 23472 XM_029340509.2 0 0 0 25 0 Q5XIN7 1.04e-171 Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGnT1) (EC 2.4.1.-) Rattus norvegicus (Rat) O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493] GO:0000139; GO:0006493; GO:0008375; GO:0016020; GO:0016266; GO:0030145; GO:0047223 23473 XM_029344725.2 0 0 0 106 49 Q5R2J4 8.66e-76 Protein APCDD1 (Adenomatosis polyposis coli down-regulated 1 protein homolog) (PsAPCDD1) Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis) negative regulation of Wnt signaling pathway [GO:0030178]; Wnt signaling pathway [GO:0016055] GO:0005615; GO:0005886; GO:0016055; GO:0017147; GO:0030178 23474 XM_044319138.1 791 448 369 1154 588 NA NA NA NA NA NA 23475 XR_003825646.2 11 5 0 6 0 NA NA NA NA NA NA 23476 XR_006394837.1 32 1 6 5 0 NA NA NA NA NA NA 23477 XM_029355463.2 2420 3497 1445 1992 2443 NA NA NA NA NA NA 23478 XM_044325609.1 46 20 35 0 85 B8VIU6 1.78e-56 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 23479 XM_044308996.1 3 0 32 96 17 NA NA NA NA NA NA 23480 XM_044327640.1 228 1 260 445 0 Q0P5W1 0 Vacuolar protein sorting-associated protein 8 homolog Mus musculus (Mouse) endosomal vesicle fusion [GO:0034058]; protein targeting to vacuole [GO:0006623] GO:0005769; GO:0006623; GO:0033263; GO:0034058; GO:0046872 23481 XM_044323483.1 3572 3477 1919 2684 2428 A4IFW2 0 Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) Danio rerio (Zebrafish) (Brachydanio rerio) peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; sensory neuron axon guidance [GO:0097374]; synaptic membrane adhesion [GO:0099560] GO:0004725; GO:0006470; GO:0008201; GO:0016020; GO:0035335; GO:0097374; GO:0099560 23482 XM_044323483.1 3572 3477 1919 2684 2428 A4IFW2 7.07e-37 Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) Danio rerio (Zebrafish) (Brachydanio rerio) peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; sensory neuron axon guidance [GO:0097374]; synaptic membrane adhesion [GO:0099560] GO:0004725; GO:0006470; GO:0008201; GO:0016020; GO:0035335; GO:0097374; GO:0099560 23483 XM_044323483.1 3572 3477 1919 2684 2428 A4IFW2 1.64e-33 Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) Danio rerio (Zebrafish) (Brachydanio rerio) peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; sensory neuron axon guidance [GO:0097374]; synaptic membrane adhesion [GO:0099560] GO:0004725; GO:0006470; GO:0008201; GO:0016020; GO:0035335; GO:0097374; GO:0099560 23484 XM_044323976.1 900 899 576 883 855 E1BNS6 3.59e-25 Sperm-associated antigen 8 Bos taurus (Bovine) cell cycle [GO:0007049]; cell differentiation [GO:0030154]; positive regulation of protein binding [GO:0032092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; single fertilization [GO:0007338]; spermatogenesis [GO:0007283] GO:0001669; GO:0001673; GO:0005634; GO:0005737; GO:0005819; GO:0005879; GO:0007049; GO:0007283; GO:0007338; GO:0008017; GO:0030154; GO:0032092; GO:0045944 23485 XM_029330184.2 11157 10028 6936 10004 9708 Q9TTR7 0 COUP transcription factor 2 (COUP-TF2) (COUP transcription factor II) (COUP-TF II) (Nuclear receptor subfamily 2 group F member 2) Bos taurus (Bovine) anatomical structure development [GO:0048856]; anterior/posterior pattern specification [GO:0009952]; blood vessel morphogenesis [GO:0048514]; cell differentiation [GO:0030154]; female gonad development [GO:0008585]; fertilization [GO:0009566]; forebrain development [GO:0030900]; interneuron migration [GO:1904936]; lymphatic endothelial cell fate commitment [GO:0060838]; maternal placenta development [GO:0001893]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of transcription by RNA polymerase II [GO:0000122]; placenta blood vessel development [GO:0060674]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; radial pattern formation [GO:0009956]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal muscle tissue development [GO:0007519]; trophoblast giant cell differentiation [GO:0060707] GO:0000122; GO:0000978; GO:0001893; GO:0001937; GO:0001972; GO:0004879; GO:0005654; GO:0005829; GO:0006357; GO:0007519; GO:0008270; GO:0008585; GO:0009566; GO:0009952; GO:0009956; GO:0010596; GO:0030154; GO:0030900; GO:0042803; GO:0045736; GO:0045893; GO:0045944; GO:0048514; GO:0048856; GO:0060674; GO:0060707; GO:0060838; GO:1904936 23486 XM_044328208.1 429 261 244 319 470 NA NA NA NA NA NA 23487 XM_044308680.1 48 9 25 48 139 Q96RW7 4.31e-25 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 23488 XM_044308680.1 48 9 25 48 139 Q96RW7 1.39e-24 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 23489 XM_044327190.1 0 0 7 0 53 NA NA NA NA NA NA 23490 XM_029358565.2 3 0 4 22 2 NA NA NA NA NA NA 23491 XM_044328313.1 2 0 6 13 0 NA NA NA NA NA NA 23492 XM_044317900.1 0 0 0 0 63 Q6DC64 2.55e-116 RNA N6-adenosine-methyltransferase mettl16 (Methyltransferase 10 domain-containing protein) (Methyltransferase-like protein 16) (N6-adenosine-methyltransferase METTL16) (EC 2.1.1.348) (U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase) (EC 2.1.1.346) Danio rerio (Zebrafish) (Brachydanio rerio) mRNA catabolic process [GO:0006402]; mRNA destabilization [GO:0061157]; mRNA methylation [GO:0080009]; post-transcriptional regulation of gene expression [GO:0010608]; regulation of mRNA splicing, via spliceosome [GO:0048024]; rRNA base methylation [GO:0070475]; S-adenosylmethionine biosynthetic process [GO:0006556]; snRNA (adenine-N6)-methylation [GO:0120049] GO:0001734; GO:0003723; GO:0005634; GO:0005737; GO:0006402; GO:0006556; GO:0010608; GO:0030629; GO:0035613; GO:0048024; GO:0052907; GO:0061157; GO:0070475; GO:0080009; GO:0120048; GO:0120049 23493 XM_044319935.1 922 1293 1458 2089 1985 Q68DA7 8.49e-70 Formin-1 (Limb deformity protein homolog) Homo sapiens (Human) actin nucleation [GO:0045010]; forelimb morphogenesis [GO:0035136]; gene expression [GO:0010467]; hindlimb morphogenesis [GO:0035137]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of actin nucleation [GO:0051127]; positive regulation of focal adhesion assembly [GO:0051894]; skeletal system morphogenesis [GO:0048705]; ureteric bud invasion [GO:0072092] GO:0003779; GO:0005634; GO:0005737; GO:0005789; GO:0005884; GO:0005886; GO:0005912; GO:0008017; GO:0010467; GO:0017124; GO:0030838; GO:0035136; GO:0035137; GO:0045010; GO:0048705; GO:0051127; GO:0051894; GO:0072092 23494 XR_003823098.2 0 0 0 31 0 NA NA NA NA NA NA 23495 XR_006394247.1 48 72 22 201 88 NA NA NA NA NA NA 23496 XM_044314798.1 0 5 4 0 7 Q09575 2.81e-33 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 23497 XR_006392945.1 41 2 25 5 151 NA NA NA NA NA NA 23498 XM_044307921.1 0 0 0 0 6 NA NA NA NA NA NA 23499 XM_044308339.1 911 554 394 763 857 Q9HCS5 7.04e-108 Band 4.1-like protein 4A (Erythrocyte membrane protein band 4.1-like 4A) (Protein NBL4) Homo sapiens (Human) actomyosin structure organization [GO:0031032] GO:0005737; GO:0005856; GO:0008092; GO:0031032 23500 XM_044312639.1 0 0 2 0 7 NA NA NA NA NA NA 23501 XM_029332676.2 29752 25352 22847 35353 34497 Q5TGI0 2.42e-29 Failed axon connections homolog Homo sapiens (Human) NA GO:0005737; GO:0016020 23502 XR_006395565.1 0 0 3 0 7 NA NA NA NA NA NA 23503 XM_029333048.2 361 429 352 253 231 Q9Z1N2 3.94e-155 Origin recognition complex subunit 1 Mus musculus (Mouse) DNA replication [GO:0006260]; DNA replication initiation [GO:0006270]; mitotic DNA replication checkpoint signaling [GO:0033314]; positive regulation of G0 to G1 transition [GO:0070318]; positive regulation of smooth muscle cell proliferation [GO:0048661] GO:0000781; GO:0000808; GO:0003677; GO:0003682; GO:0003688; GO:0005524; GO:0005634; GO:0005654; GO:0005664; GO:0006260; GO:0006270; GO:0016887; GO:0033314; GO:0046872; GO:0048661; GO:0070318 23504 XR_006397878.1 155 6 132 23 778 NA NA NA NA NA NA 23505 XM_029326730.2 2 14 13 11 3 NA NA NA NA NA NA 23506 XM_029351433.2 313 326 147 356 428 Q9BRP4 9.16e-116 Proteasomal ATPase-associated factor 1 (Protein G-16) (WD repeat-containing protein 71) Homo sapiens (Human) NA GO:0000502 23507 XM_029353039.2 178 76 159 164 216 NA NA NA NA NA NA 23508 XM_029344220.2 100 37 51 0 26 O95263 0 High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B (HsPDE8B) (EC 3.1.4.53) (Cell proliferation-inducing gene 22 protein) Homo sapiens (Human) behavioral fear response [GO:0001662]; cAMP catabolic process [GO:0006198]; negative regulation of steroid hormone biosynthetic process [GO:0090032]; neuromuscular process controlling balance [GO:0050885]; operant conditioning [GO:0035106]; signal transduction [GO:0007165]; visual learning [GO:0008542] GO:0001662; GO:0004114; GO:0004115; GO:0005829; GO:0006198; GO:0007165; GO:0008542; GO:0035106; GO:0046872; GO:0050885; GO:0090032 23509 XM_044320379.1 208 0 1544 1048 1756 Q14517 0 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 23510 XM_044320379.1 208 0 1544 1048 1756 Q14517 6.54e-55 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 23511 XM_044320379.1 208 0 1544 1048 1756 Q14517 1.08e-34 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 23512 XM_029325232.2 6 0 7 0 0 NA NA NA NA NA NA 23513 XR_006394125.1 0 0 0 0 8 NA NA NA NA NA NA 23514 XM_029336407.2 7435 4749 3116 6677 6112 Q9UKN7 0 Unconventional myosin-XV (Unconventional myosin-15) Homo sapiens (Human) actin filament organization [GO:0007015]; inner ear morphogenesis [GO:0042472]; locomotory behavior [GO:0007626]; response to light stimulus [GO:0009416]; sensory perception of sound [GO:0007605]; vesicle transport along actin filament [GO:0030050] GO:0000146; GO:0005516; GO:0005524; GO:0005737; GO:0007015; GO:0007605; GO:0007626; GO:0009416; GO:0015629; GO:0016459; GO:0030050; GO:0031982; GO:0032420; GO:0042472; GO:0051015; GO:0070062; GO:0098858 23515 XM_029336407.2 7435 4749 3116 6677 6112 Q9UKN7 2.97e-128 Unconventional myosin-XV (Unconventional myosin-15) Homo sapiens (Human) actin filament organization [GO:0007015]; inner ear morphogenesis [GO:0042472]; locomotory behavior [GO:0007626]; response to light stimulus [GO:0009416]; sensory perception of sound [GO:0007605]; vesicle transport along actin filament [GO:0030050] GO:0000146; GO:0005516; GO:0005524; GO:0005737; GO:0007015; GO:0007605; GO:0007626; GO:0009416; GO:0015629; GO:0016459; GO:0030050; GO:0031982; GO:0032420; GO:0042472; GO:0051015; GO:0070062; GO:0098858 23516 XR_006394074.1 0 21 2 1 0 NA NA NA NA NA NA 23517 XM_029335715.2 1457 0 0 187 61 Q9NZM1 0 Myoferlin (Fer-1-like protein 3) Homo sapiens (Human) blood circulation [GO:0008015]; membrane fusion [GO:0061025]; muscle contraction [GO:0006936]; plasma membrane organization [GO:0007009]; plasma membrane repair [GO:0001778]; T-tubule organization [GO:0033292] GO:0001778; GO:0005543; GO:0005635; GO:0005886; GO:0005901; GO:0006936; GO:0007009; GO:0008015; GO:0030659; GO:0031410; GO:0031965; GO:0033292; GO:0043231; GO:0046872; GO:0061025; GO:0070062 23518 XR_006397141.1 30 35 0 0 266 NA NA NA NA NA NA 23519 XM_044325927.1 651 535 493 722 539 Q7T0Y4 0 Dynein regulatory complex protein 1 (Coiled-coil domain-containing protein 164) Xenopus laevis (African clawed frog) axonemal dynein complex assembly [GO:0070286]; cilium-dependent cell motility [GO:0060285] GO:0005858; GO:0005930; GO:0031514; GO:0060285; GO:0070286 23520 XR_003825503.2 43 10 16 5 13 NA NA NA NA NA NA 23521 XM_044320391.1 1 9 6 29 6 NA NA NA NA NA NA 23522 XM_029357255.2 823 1063 1187 945 837 P56224 1.62e-70 POU domain, class 3, transcription factor 3-A (Brain-specific homeobox/POU domain protein 1.1) (Brain-1.1) (zfBrn-1.1) (Class III POU domain protein taichi) (POU domain protein 12) (ZP-12) Danio rerio (Zebrafish) (Brachydanio rerio) brain development [GO:0007420]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0007420 23523 XR_006396220.1 2 0 20 19 59 NA NA NA NA NA NA 23524 XM_029355323.2 887 1256 899 560 402 G8HTB6 3.03e-28 ZP domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 23525 XM_044328590.1 22 52 49 22 97 NA NA NA NA NA NA 23526 XM_044321274.1 47 880 225 9 2 NA NA NA NA NA NA 23527 XM_044313359.1 163 0 67 100 0 A1WS32 1.13e-66 Putative hydro-lyase Veis_4744 (EC 4.2.1.-) Verminephrobacter eiseniae (strain EF01-2) NA GO:0016829 23528 XM_044325777.1 0 0 0 10 2 NA NA NA NA NA NA 23529 XM_044320269.1 821 694 512 642 769 Q28CH8 1.37e-95 Protein YIPF6 (YIP1 family member 6) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888] GO:0000138; GO:0000139; GO:0005797; GO:0005802; GO:0006888 23530 XM_044312697.1 33 35 23 163 15 NA NA NA NA NA NA 23531 XM_044324889.1 134 91 80 44 69 Q26626 0 Kinesin-associated protein 3 (SpKAP115) Strongylocentrotus purpuratus (Purple sea urchin) cilium organization [GO:0044782]; microtubule-based movement [GO:0007018]; microtubule-based process [GO:0007017] GO:0005930; GO:0007017; GO:0007018; GO:0016939; GO:0019894; GO:0035869; GO:0044782 23532 XM_044323890.1 30 71 250 218 56 NA NA NA NA NA NA 23533 XM_044317574.1 31 25 6 17 16 Q80XJ3 1.42e-73 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 23534 XM_044317574.1 31 25 6 17 16 Q80XJ3 1.09e-65 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 23535 XM_044317574.1 31 25 6 17 16 Q80XJ3 1.43e-65 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 23536 XM_044317574.1 31 25 6 17 16 Q80XJ3 1.56e-63 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 23537 XM_044317574.1 31 25 6 17 16 Q80XJ3 3.31e-63 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 23538 XM_044317574.1 31 25 6 17 16 Q80XJ3 5.07e-61 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 23539 XM_044317574.1 31 25 6 17 16 Q80XJ3 3.26e-56 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 23540 XM_044317574.1 31 25 6 17 16 Q80XJ3 1.5e-51 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 23541 XM_044317574.1 31 25 6 17 16 Q80XJ3 1.99e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 23542 XM_029351490.2 3 0 2 7 33 NA NA NA NA NA NA 23543 XM_044310120.1 428 486 590 460 506 NA NA NA NA NA NA 23544 XR_006396645.1 92 0 8 15 5 NA NA NA NA NA NA 23545 XR_003826041.2 58 89 25 48 25 NA NA NA NA NA NA 23546 XM_044308154.1 23 0 7 6 10 NA NA NA NA NA NA 23547 XR_006398200.1 7059 8849 6963 22673 11081 NA NA NA NA NA NA 23548 XR_006392648.1 18 40 57 115 84 NA NA NA NA NA NA 23549 XM_029329474.2 5 0 22 1 22 NA NA NA NA NA NA 23550 XM_029341518.2 332 204 171 213 332 Q8R5F3 1.86e-26 ADP-ribose glycohydrolase OARD1 (O-acetyl-ADP-ribose deacetylase 1) (EC 3.5.1.-) (Terminal ADP-ribose protein glycohydrolase 1) ([Protein ADP-ribosylglutamate] hydrolase OARD1) (EC 3.2.2.-) Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; peptidyl-glutamate ADP-deribosylation [GO:0140291]; protein de-ADP-ribosylation [GO:0051725]; purine nucleoside metabolic process [GO:0042278] GO:0001883; GO:0005654; GO:0005730; GO:0006974; GO:0042278; GO:0051725; GO:0061463; GO:0090734; GO:0140291; GO:0140293 23551 XM_044324464.1 65 2949 1280 763 39 NA NA NA NA NA NA 23552 XR_006395101.1 650 448 342 525 245 NA NA NA NA NA NA 23553 XM_029340266.2 0 0 11 0 0 E7FAM5 1.4e-105 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 23554 XR_006396025.1 8 138 0 0 154 NA NA NA NA NA NA 23555 XM_029357203.2 134 276 141 59 15 NA NA NA NA NA NA 23556 XM_044320007.1 277 300 94 110 121 Q9JI70 5.1e-69 Molecular chaperone MKKS (McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin) (Protein Bbs6 homolog) Mus musculus (Mouse) artery smooth muscle contraction [GO:0014824]; brain morphogenesis [GO:0048854]; cartilage development [GO:0051216]; cerebral cortex development [GO:0021987]; chaperone-mediated protein complex assembly [GO:0051131]; cilium assembly [GO:0060271]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; developmental process [GO:0032502]; face development [GO:0060324]; fat cell differentiation [GO:0045444]; gene expression [GO:0010467]; hippocampus development [GO:0021766]; intracellular transport [GO:0046907]; leptin-mediated signaling pathway [GO:0033210]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of appetite by leptin-mediated signaling pathway [GO:0038108]; negative regulation of blood pressure [GO:0045776]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of multicellular organism growth [GO:0040018]; protein folding [GO:0006457]; regulation of cilium beat frequency involved in ciliary motility [GO:0060296]; regulation of stress fiber assembly [GO:0051492]; response to leptin [GO:0044321]; sensory perception of smell [GO:0007608]; social behavior [GO:0035176]; spermatid development [GO:0007286]; striatum development [GO:0021756]; vasodilation [GO:0042311] GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0006457; GO:0007286; GO:0007608; GO:0010467; GO:0010629; GO:0014824; GO:0021756; GO:0021766; GO:0021987; GO:0030837; GO:0031514; GO:0032502; GO:0033210; GO:0034260; GO:0035176; GO:0036064; GO:0038108; GO:0040018; GO:0042311; GO:0044321; GO:0045444; GO:0045494; GO:0045776; GO:0046907; GO:0048854; GO:0050910; GO:0051082; GO:0051131; GO:0051216; GO:0051492; GO:0060271; GO:0060296; GO:0060324; GO:0061629; GO:1902636; GO:1905515 23557 XR_006392634.1 21 0 17 3 3 NA NA NA NA NA NA 23558 XM_044320039.1 197 28 41 49 206 NA NA NA NA NA NA 23559 XM_029350370.2 491 890 574 580 436 A9UMG5 9.59e-81 Protein IMPACT-B (Imprinted and ancient gene protein homolog B) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cellular response to acidic pH [GO:0071468]; cellular response to amino acid starvation [GO:0034198]; cellular response to benomyl [GO:0072755]; cellular response to glucose starvation [GO:0042149]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to leucine starvation [GO:1990253]; cellular response to UV-C [GO:0071494]; GCN2-mediated signaling [GO:0140469]; negative regulation of cell death [GO:0060548]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; neuron projection extension [GO:1990138]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of translational initiation in response to starvation [GO:0071264] GO:0000122; GO:0001933; GO:0005737; GO:0005844; GO:0031333; GO:0031953; GO:0034198; GO:0042149; GO:0045666; GO:0060548; GO:0070301; GO:0071264; GO:0071468; GO:0071494; GO:0072755; GO:0097201; GO:0140469; GO:1990138; GO:1990253 23560 XM_044315478.1 0 0 19 37 2 NA NA NA NA NA NA 23561 XM_044310556.1 3 58 14 16 27 NA NA NA NA NA NA 23562 XM_044319743.1 8757 8678 4988 8892 6733 Q8QGW7 4.54e-24 Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog (LPS-induced TNF-alpha factor homolog) (Small integral membrane protein of lysosome/late endosome) Gallus gallus (Chicken) cytokine production [GO:0001816]; sexual reproduction [GO:0019953] GO:0000139; GO:0001816; GO:0003677; GO:0005125; GO:0005634; GO:0005765; GO:0008270; GO:0009898; GO:0019953; GO:0098559; GO:0098560; GO:0098574 23563 XM_044317203.1 741 3 360 648 498 Q6DCD5 0 Protein O-mannosyl-transferase TMTC2 (EC 2.4.1.109) (Transmembrane and TPR repeat-containing protein 2) Xenopus laevis (African clawed frog) protein O-linked mannosylation [GO:0035269] GO:0000030; GO:0004169; GO:0005783; GO:0016020; GO:0035269 23564 XM_029352418.2 0 0 142 0 0 A6H603 4.96e-92 NACHT domain- and WD repeat-containing protein 1 Mus musculus (Mouse) negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of gene expression [GO:0010628] GO:0005524; GO:0005730; GO:0005829; GO:0010628; GO:0032088 23565 XM_044323122.1 864 28 20 6 107 NA NA NA NA NA NA 23566 XM_044321508.1 0 33 17 18 0 NA NA NA NA NA NA 23567 XM_029334579.2 963 544 258 792 1045 Q9UKP5 3.67e-123 A disintegrin and metalloproteinase with thrombospondin motifs 6 (ADAM-TS 6) (ADAM-TS6) (ADAMTS-6) (EC 3.4.24.-) Homo sapiens (Human) aorta development [GO:0035904]; cardiac septum development [GO:0003279]; coronary vasculature development [GO:0060976]; extracellular matrix organization [GO:0030198]; kidney development [GO:0001822]; proteolysis [GO:0006508] GO:0001822; GO:0003279; GO:0004222; GO:0005576; GO:0006508; GO:0008237; GO:0030198; GO:0031012; GO:0035904; GO:0046872; GO:0060976 23568 XM_044308045.1 0 70 53 77 134 P24155 0 Thimet oligopeptidase (EC 3.4.24.15) (Endo-oligopeptidase A) (Endopeptidase 24.15) (PZ-peptidase) (Soluble metallo-endopeptidase) Rattus norvegicus (Rat) intracellular signal transduction [GO:0035556]; peptide catabolic process [GO:0043171]; peptide metabolic process [GO:0006518]; proteolysis [GO:0006508] GO:0004222; GO:0005758; GO:0006508; GO:0006518; GO:0008233; GO:0035556; GO:0042277; GO:0043171; GO:0046872 23569 XM_044320985.1 0 0 30 0 0 NA NA NA NA NA NA 23570 XM_044317025.1 61 39 30 123 150 Q9I8C7 4.2e-87 Neuronal acetylcholine receptor subunit alpha-10 (Alpha 10 nAChR) (Nicotinic acetylcholine receptor subunit alpha-10) (NACHR alpha-10) Gallus gallus (Chicken) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; response to auditory stimulus [GO:0010996]; signal transduction [GO:0007165] GO:0004888; GO:0005231; GO:0005262; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0010996; GO:0022848; GO:0030594; GO:0034220; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051899; GO:1904315 23571 XM_044319789.1 101 33 24 89 94 Q9P2E3 1.32e-119 NFX1-type zinc finger-containing protein 1 Homo sapiens (Human) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 23572 XM_044319789.1 101 33 24 89 94 Q9P2E3 1.56e-81 NFX1-type zinc finger-containing protein 1 Homo sapiens (Human) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 23573 XM_044319789.1 101 33 24 89 94 Q9P2E3 1.75e-67 NFX1-type zinc finger-containing protein 1 Homo sapiens (Human) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 23574 XM_044319789.1 101 33 24 89 94 Q9P2E3 4.6e-21 NFX1-type zinc finger-containing protein 1 Homo sapiens (Human) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 23575 XM_029336169.2 29 59 29 78 50 NA NA NA NA NA NA 23576 XR_006392219.1 32 2 39 32 73 NA NA NA NA NA NA 23577 XM_029334001.2 23 3 5 16 28 Q92051 1.14e-46 Carbonic anhydrase (EC 4.2.1.1) (Carbonate dehydratase) Danio rerio (Zebrafish) (Brachydanio rerio) carbon dioxide transport [GO:0015670]; hypotonic salinity response [GO:0042539]; one-carbon metabolic process [GO:0006730] GO:0004089; GO:0005737; GO:0006730; GO:0008270; GO:0015670; GO:0016836; GO:0042539 23578 XR_003824795.2 38 41 25 7 14 NA NA NA NA NA NA 23579 XM_029345173.2 8 42 7 16 38 NA NA NA NA NA NA 23580 XM_044325361.1 61 0 0 66 11 NA NA NA NA NA NA 23581 XR_006395128.1 569 528 363 690 590 NA NA NA NA NA NA 23582 XM_029341578.2 2234 2146 1404 2435 2584 NA NA NA NA NA NA 23583 XR_003826717.2 222 311 137 261 222 NA NA NA NA NA NA 23584 XM_029324684.2 37 0 0 69 152 O46470 4.97e-171 Regulator of G-protein signaling 7 (RGS7) Bos taurus (Bovine) G protein-coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; regulation of G protein-coupled receptor signaling pathway [GO:0008277] GO:0005096; GO:0005737; GO:0005829; GO:0005886; GO:0007186; GO:0008277; GO:0009968; GO:0031681; GO:0035556; GO:0043005; GO:0043547 23585 XM_029338120.2 1875 1225 1191 1436 1547 Q5R573 2e-93 Rab-like protein 2A Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003924; GO:0005525 23586 XM_044311742.1 3 15 33 25 165 Q09575 8.37e-41 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 23587 XR_003823881.2 30 0 8 19 12 NA NA NA NA NA NA 23588 XM_029343911.2 194 73 67 109 64 Q6DDT4 3.11e-166 NA NA NA NA 23589 XM_044315211.1 0 0 0 2 9 Q91175 8.88e-43 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (MAR1) Oryzias latipes (Japanese rice fish) (Japanese killifish) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of vasoconstriction [GO:0045907] GO:0001996; GO:0004930; GO:0004937; GO:0005886; GO:0007200; GO:0007204; GO:0007267; GO:0043410; GO:0045907; GO:0071880 23590 XM_029337065.2 0 0 0 198 214 Q4V8E5 1.53e-28 Major facilitator superfamily domain-containing protein 3 Rattus norvegicus (Rat) NA GO:0015295; GO:0016020 23591 XR_006391710.1 27 45 49 24 153 NA NA NA NA NA NA 23592 XM_044321963.1 62 294 198 191 97 Q9HF54 4.85e-40 GTP-binding protein RHO1 Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii) actin filament organization [GO:0007015]; cortical cytoskeleton organization [GO:0030865]; establishment or maintenance of cell polarity [GO:0007163]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; small GTPase mediated signal transduction [GO:0007264] GO:0003924; GO:0005525; GO:0005856; GO:0005886; GO:0005938; GO:0007015; GO:0007163; GO:0007264; GO:0008360; GO:0019901; GO:0030865; GO:0031410; GO:0032956; GO:0042995 23593 XM_029340279.2 84 14 0 17 31 Q5RA50 2.93e-26 Protein FAM124A Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA NA 23594 XM_029358068.2 0 0 0 0 17 Q5ZKY2 0 Ubiquitin-like modifier-activating enzyme ATG7 (ATG12-activating enzyme E1 ATG7) (Autophagy-related protein 7) (APG7-like) Gallus gallus (Chicken) autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; C-terminal protein lipidation [GO:0006501]; cellular response to nitrogen starvation [GO:0006995]; late nucleophagy [GO:0044805]; piecemeal microautophagy of the nucleus [GO:0034727]; protein modification by small protein conjugation [GO:0032446]; protein transport [GO:0015031]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511] GO:0000045; GO:0000407; GO:0000422; GO:0005737; GO:0006501; GO:0006914; GO:0006995; GO:0015031; GO:0019778; GO:0019779; GO:0032446; GO:0034727; GO:0042752; GO:0044805; GO:0048511 23595 XR_006396773.1 51 444 732 274 193 NA NA NA NA NA NA 23596 XM_029333744.2 1082 494 631 598 502 Q61176 3.81e-92 Arginase-1 (EC 3.5.3.1) (Liver-type arginase) (Type I arginase) Mus musculus (Mouse) adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; negative regulation of type II interferon-mediated signaling pathway [GO:0060336]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; regulation of L-arginine import across plasma membrane [GO:1905541]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to xenobiotic stimulus [GO:0009410]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050] GO:0000050; GO:0001889; GO:0001938; GO:0002250; GO:0004053; GO:0005615; GO:0005737; GO:0005741; GO:0005829; GO:0006525; GO:0007568; GO:0009410; GO:0009635; GO:0010042; GO:0010043; GO:0010269; GO:0014075; GO:0019547; GO:0030145; GO:0030324; GO:0032964; GO:0033189; GO:0033197; GO:0042130; GO:0042802; GO:0042832; GO:0043005; GO:0043025; GO:0043200; GO:0045087; GO:0046007; GO:0046686; GO:0048678; GO:0051597; GO:0060056; GO:0060135; GO:0060336; GO:0070301; GO:0070965; GO:0071222; GO:0071353; GO:0071377; GO:0071549; GO:0071560; GO:1905541; GO:2000552 23597 XM_029351289.2 231 316 211 353 191 Q6YI46 2.02e-65 Transmembrane protein 64 Homo sapiens (Human) negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of osteoblast differentiation [GO:0045668]; osteoclast differentiation [GO:0030316]; positive regulation of bone resorption [GO:0045780]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of osteoclast differentiation [GO:0045672]; regulation of ATP-dependent activity [GO:0043462]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0005783; GO:0016020; GO:0030316; GO:0043462; GO:0045600; GO:0045668; GO:0045672; GO:0045780; GO:0051480; GO:0090090 23598 XM_029345240.2 393 532 390 306 370 NA NA NA NA NA NA 23599 XM_044311341.1 0 0 0 18 11 B0S5N4 1.85e-126 Plexin A3 Danio rerio (Zebrafish) (Brachydanio rerio) axon extension [GO:0048675]; branching morphogenesis of a nerve [GO:0048755]; embryonic skeletal joint morphogenesis [GO:0060272]; motor neuron axon guidance [GO:0008045]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of collateral sprouting in absence of injury [GO:0048696]; regulation of GTPase activity [GO:0043087]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287] GO:0002116; GO:0005886; GO:0007162; GO:0008045; GO:0008360; GO:0016020; GO:0017154; GO:0030334; GO:0042802; GO:0043087; GO:0048675; GO:0048696; GO:0048755; GO:0050772; GO:0060272; GO:1902287 23600 XM_029357324.2 350 0 155 305 463 Q6VAB6 9.08e-85 Kinase suppressor of Ras 2 (hKSR2) (EC 2.7.11.1) Homo sapiens (Human) calcium-mediated signaling [GO:0019722]; positive regulation of cold-induced thermogenesis [GO:0120162]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; signal transduction [GO:0007165] GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006468; GO:0007165; GO:0007265; GO:0019722; GO:0046872; GO:0106310; GO:0120162 23601 XM_029357324.2 350 0 155 305 463 Q6VAB6 3.09e-22 Kinase suppressor of Ras 2 (hKSR2) (EC 2.7.11.1) Homo sapiens (Human) calcium-mediated signaling [GO:0019722]; positive regulation of cold-induced thermogenesis [GO:0120162]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; signal transduction [GO:0007165] GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006468; GO:0007165; GO:0007265; GO:0019722; GO:0046872; GO:0106310; GO:0120162 23602 XM_029350839.2 378 169 245 273 568 P55112 7.13e-46 Zinc metalloproteinase nas-4 (EC 3.4.24.-) (Nematode astacin 4) Caenorhabditis elegans proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0006508; GO:0008270 23603 XM_029357722.2 199 157 91 209 103 Q15034 2.49e-24 Probable E3 ubiquitin-protein ligase HERC3 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 3) (HECT-type E3 ubiquitin transferase HERC3) Homo sapiens (Human) protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0005737; GO:0005829; GO:0006511; GO:0016567; GO:0031410; GO:0061630 23604 XM_044311801.1 0 4 0 22 5 B8VIU6 6.75e-42 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 23605 XM_029358127.2 5023 3222 2533 4485 4523 O55012 1.78e-136 Phosphatidylinositol-binding clathrin assembly protein (Clathrin assembly lymphoid myeloid leukemia protein) (rCALM) Rattus norvegicus (Rat) amyloid-beta clearance by transcytosis [GO:0150093]; axonogenesis [GO:0007409]; clathrin coat assembly [GO:0048268]; clathrin-coated pit assembly [GO:1905224]; clathrin-dependent endocytosis [GO:0072583]; dendrite morphogenesis [GO:0048813]; endocytosis [GO:0006897]; endosomal transport [GO:0016197]; hemopoiesis [GO:0030097]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; membrane bending [GO:0097753]; negative regulation of gene expression [GO:0010629]; negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902963]; negative regulation of protein localization to cell surface [GO:2000009]; negative regulation of protein localization to plasma membrane [GO:1903077]; negative regulation of receptor-mediated endocytosis [GO:0048261]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of axonogenesis [GO:0050772]; positive regulation of dendrite extension [GO:1903861]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron death [GO:1901216]; positive regulation of synaptic vesicle clustering [GO:2000809]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902959]; regulation of endocytosis [GO:0030100]; regulation of protein localization [GO:0032880]; regulation of protein transport [GO:0051223]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle transport [GO:1902803]; regulation of terminal button organization [GO:2000331]; regulation of vesicle size [GO:0097494]; synaptic vesicle budding from presynaptic endocytic zone membrane [GO:0016185]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle maturation [GO:0016188]; vesicle budding from membrane [GO:0006900]; vesicle cargo loading [GO:0035459]; vesicle-mediated transport [GO:0016192] GO:0000149; GO:0005545; GO:0005546; GO:0005634; GO:0005768; GO:0005769; GO:0005794; GO:0005886; GO:0005905; GO:0006897; GO:0006898; GO:0006900; GO:0007409; GO:0007611; GO:0008021; GO:0009986; GO:0010629; GO:0014069; GO:0016020; GO:0016185; GO:0016188; GO:0016192; GO:0016197; GO:0017124; GO:0030097; GO:0030100; GO:0030132; GO:0030136; GO:0030276; GO:0031267; GO:0031623; GO:0031982; GO:0032050; GO:0032880; GO:0035459; GO:0042734; GO:0042802; GO:0043005; GO:0043025; GO:0043547; GO:0045202; GO:0045211; GO:0045893; GO:0048156; GO:0048261; GO:0048268; GO:0048488; GO:0048813; GO:0050750; GO:0050772; GO:0051223; GO:0055072; GO:0070381; GO:0072583; GO:0097418; GO:0097494; GO:0097753; GO:0098685; GO:0098688; GO:0098794; GO:0098894; GO:0150093; GO:1900242; GO:1900244; GO:1901216; GO:1902004; GO:1902803; GO:1902959; GO:1902961; GO:1902963; GO:1903077; GO:1903861; GO:1905224; GO:2000009; GO:2000331; GO:2000809 23606 XM_029339781.2 11361 6734 4525 10111 12205 Q3SZB4 0 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (MCAD) (EC 1.3.8.7) Bos taurus (Bovine) cardiac muscle cell differentiation [GO:0055007]; carnitine biosynthetic process [GO:0045329]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; glycogen biosynthetic process [GO:0005978]; liver development [GO:0001889]; medium-chain fatty acid catabolic process [GO:0051793]; post-embryonic development [GO:0009791]; regulation of gluconeogenesis [GO:0006111]; response to cold [GO:0009409]; response to starvation [GO:0042594] GO:0001889; GO:0003995; GO:0005737; GO:0005739; GO:0005759; GO:0005978; GO:0006111; GO:0006635; GO:0009409; GO:0009791; GO:0019254; GO:0030424; GO:0031966; GO:0033539; GO:0042594; GO:0042802; GO:0045329; GO:0050660; GO:0051793; GO:0055007; GO:0070991 23607 XM_044309134.1 174 192 235 25 173 NA NA NA NA NA NA 23608 XM_044315974.1 153 105 38 74 129 P81274 3.01e-43 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 23609 XM_044315974.1 153 105 38 74 129 P81274 6.04e-41 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 23610 XM_044315974.1 153 105 38 74 129 P81274 6.25e-32 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 23611 XM_044328632.1 560 545 359 813 1041 NA NA NA NA NA NA 23612 XM_029344860.2 4179 3057 3767 2480 2588 NA NA NA NA NA NA 23613 XM_044317309.1 14 0 0 0 2 A0A2B4SJA1 1.87e-121 NA NA NA NA 23614 XM_044318716.1 445 538 413 463 408 Q5F362 1.11e-104 Cell cycle control protein 50A (P4-ATPase flippase complex beta subunit TMEM30A) (Transmembrane protein 30A) Gallus gallus (Chicken) phospholipid translocation [GO:0045332] GO:0001750; GO:0001917; GO:0005783; GO:0005794; GO:0005886; GO:0016324; GO:0030658; GO:0045332; GO:1990531 23615 XM_029348324.2 547 254 78 331 231 NA NA NA NA NA NA 23616 XR_006394579.1 0 0 0 27 1 NA NA NA NA NA NA 23617 XM_029335731.2 27 9 1 3 19 NA NA NA NA NA NA 23618 XM_044320784.1 14 15 31 12 24 Q8BQH6 8.75e-22 CUB domain-containing protein 2 Mus musculus (Mouse) NA GO:0005576 23619 XM_044323350.1 109 38 47 67 17 NA NA NA NA NA NA 23620 XR_006393000.1 41 2 25 5 151 NA NA NA NA NA NA 23621 XR_003825236.2 0 5 13 1 1 NA NA NA NA NA NA 23622 XM_029356111.2 1297 1000 953 989 719 Q6QD59 1.87e-58 Vesicle transport protein SEC20 Mus musculus (Mouse) apoptotic process [GO:0006915]; endoplasmic reticulum membrane fusion [GO:0016320]; endoplasmic reticulum organization [GO:0007029]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] GO:0005484; GO:0005635; GO:0005737; GO:0005783; GO:0005789; GO:0006890; GO:0006915; GO:0007029; GO:0015031; GO:0016320; GO:0030137; GO:0031201; GO:0031966; GO:0043231 23623 XM_029342044.2 1148 759 200 1388 1535 Q90683 9.74e-36 Transcription factor 4 (TCF-4) (Class A helix-loop-helix transcription factor GE2) Gallus gallus (Chicken) positive regulation of neuron differentiation [GO:0045666]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005667; GO:0006357; GO:0045666; GO:0046982; GO:0070888 23624 XM_029325661.2 2 0 1 0 8 NA NA NA NA NA NA 23625 XM_044310156.1 385 153 160 5 385 P14381 2.68e-29 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 23626 XM_029340482.2 0 0 10 0 9 Q9NXD2 7.04e-68 Myotubularin-related protein 10 (Inactive phosphatidylinositol 3-phosphatase 10) Homo sapiens (Human) phosphatidylinositol dephosphorylation [GO:0046856] GO:0004438; GO:0005737; GO:0005829; GO:0046856 23627 XM_044314683.1 3 3 0 0 11 NA NA NA NA NA NA 23628 XR_003827935.2 0 0 2 0 6 NA NA NA NA NA NA 23629 XM_029328571.2 9 39 39 137 180 NA NA NA NA NA NA 23630 XM_044312143.1 0 0 0 2 7 NA NA NA NA NA NA 23631 XM_044317297.1 25 0 0 0 0 NA NA NA NA NA NA 23632 XM_044322430.1 187 163 70 115 280 NA NA NA NA NA NA 23633 XM_029338199.2 333 274 318 442 368 NA NA NA NA NA NA 23634 XR_006394895.1 60 3 95 17 77 NA NA NA NA NA NA 23635 XM_029330270.2 48 12 43 37 76 O43581 8.86e-36 Synaptotagmin-7 (IPCA-7) (Prostate cancer-associated protein 7) (Synaptotagmin VII) (SytVII) Homo sapiens (Human) calcium ion regulated lysosome exocytosis [GO:1990927]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; phagocytosis [GO:0006909]; phagosome-lysosome fusion [GO:0090385]; plasma membrane repair [GO:0001778]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; regulation of bone remodeling [GO:0046850]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of glucagon secretion [GO:0070092]; regulation of insulin secretion [GO:0050796]; regulation of phagocytosis [GO:0050764]; regulation of synaptic vesicle endocytosis [GO:1900242]; short-term synaptic potentiation [GO:1990926]; synaptic vesicle recycling [GO:0036465]; vesicle-mediated cholesterol transport [GO:0090119]; vesicle-mediated transport [GO:0016192] GO:0000149; GO:0001778; GO:0001786; GO:0005509; GO:0005516; GO:0005544; GO:0005546; GO:0005764; GO:0005765; GO:0005777; GO:0005778; GO:0005829; GO:0005886; GO:0006909; GO:0008021; GO:0014059; GO:0016192; GO:0017156; GO:0017158; GO:0019905; GO:0030276; GO:0030670; GO:0030672; GO:0031045; GO:0032009; GO:0036465; GO:0042734; GO:0042995; GO:0045956; GO:0046850; GO:0048791; GO:0050764; GO:0050796; GO:0070062; GO:0070092; GO:0070382; GO:0071277; GO:0090119; GO:0090385; GO:0098686; GO:1900242; GO:1990926; GO:1990927 23636 XR_006397089.1 1 4 5 42 70 NA NA NA NA NA NA 23637 XM_044308331.1 5 4 2 0 6 A2A9C3 0 KICSTOR complex protein SZT2 (Seizure threshold 2 protein) (Transcript increased in glutamate resistance) (TIGR) Mus musculus (Mouse) cellular response to amino acid starvation [GO:0034198]; cellular response to glucose starvation [GO:0042149]; central nervous system development [GO:0007417]; corpus callosum morphogenesis [GO:0021540]; negative regulation of TORC1 signaling [GO:1904262]; pigmentation [GO:0043473]; post-embryonic development [GO:0009791]; protein localization to lysosome [GO:0061462]; regulation of superoxide dismutase activity [GO:1901668]; response to nutrient levels [GO:0031667] GO:0005765; GO:0005777; GO:0007417; GO:0009791; GO:0021540; GO:0031667; GO:0034198; GO:0042149; GO:0043473; GO:0061462; GO:0061700; GO:0140007; GO:1901668; GO:1904262; GO:1990130 23638 XM_044308331.1 5 4 2 0 6 A2A9C3 5.6e-91 KICSTOR complex protein SZT2 (Seizure threshold 2 protein) (Transcript increased in glutamate resistance) (TIGR) Mus musculus (Mouse) cellular response to amino acid starvation [GO:0034198]; cellular response to glucose starvation [GO:0042149]; central nervous system development [GO:0007417]; corpus callosum morphogenesis [GO:0021540]; negative regulation of TORC1 signaling [GO:1904262]; pigmentation [GO:0043473]; post-embryonic development [GO:0009791]; protein localization to lysosome [GO:0061462]; regulation of superoxide dismutase activity [GO:1901668]; response to nutrient levels [GO:0031667] GO:0005765; GO:0005777; GO:0007417; GO:0009791; GO:0021540; GO:0031667; GO:0034198; GO:0042149; GO:0043473; GO:0061462; GO:0061700; GO:0140007; GO:1901668; GO:1904262; GO:1990130 23639 XM_044308331.1 5 4 2 0 6 A2A9C3 1.05e-59 KICSTOR complex protein SZT2 (Seizure threshold 2 protein) (Transcript increased in glutamate resistance) (TIGR) Mus musculus (Mouse) cellular response to amino acid starvation [GO:0034198]; cellular response to glucose starvation [GO:0042149]; central nervous system development [GO:0007417]; corpus callosum morphogenesis [GO:0021540]; negative regulation of TORC1 signaling [GO:1904262]; pigmentation [GO:0043473]; post-embryonic development [GO:0009791]; protein localization to lysosome [GO:0061462]; regulation of superoxide dismutase activity [GO:1901668]; response to nutrient levels [GO:0031667] GO:0005765; GO:0005777; GO:0007417; GO:0009791; GO:0021540; GO:0031667; GO:0034198; GO:0042149; GO:0043473; GO:0061462; GO:0061700; GO:0140007; GO:1901668; GO:1904262; GO:1990130 23640 XM_044310254.1 0 15 0 41 81 Q9FT70 1.5e-53 ATP-dependent DNA helicase Q-like 4B (EC 3.6.4.12) (RecQ-like protein 4B) (AtRecQ4B) (AtRecQl4B) Arabidopsis thaliana (Mouse-ear cress) cellular response to cold [GO:0070417]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724] GO:0000724; GO:0003676; GO:0005524; GO:0005634; GO:0005694; GO:0005737; GO:0006268; GO:0006281; GO:0006310; GO:0009378; GO:0016887; GO:0032508; GO:0043138; GO:0046872; GO:0070417 23641 XM_029328666.2 202 179 88 96 91 NA NA NA NA NA NA 23642 XM_044323799.1 639 242 167 416 313 Q4J9D2 5.64e-42 Uncharacterized protein Saci_1252 Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770) NA NA 23643 XM_029338049.2 3604 2643 1550 2830 2187 P22758 1.41e-160 Protein-glutamine gamma-glutamyltransferase K (EC 2.3.2.13) (Epidermal TGase) (Transglutaminase K) (TG(K)) (TGK) (TGase K) (Transglutaminase-1) (TGase-1) Oryctolagus cuniculus (Rabbit) keratinization [GO:0031424]; peptide cross-linking [GO:0018149]; positive regulation of cell cycle [GO:0045787]; positive regulation of keratinocyte proliferation [GO:0010838] GO:0003810; GO:0010838; GO:0016020; GO:0018149; GO:0031424; GO:0045787; GO:0046872 23644 XM_029324590.2 540 276 314 448 348 NA NA NA NA NA NA 23645 XM_044310198.1 391 267 177 216 301 Q52KK4 3.4e-36 H/ACA ribonucleoprotein complex non-core subunit NAF1 Rattus norvegicus (Rat) box H/ACA snoRNP assembly [GO:0000493]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere maintenance via telomere lengthening [GO:1904358]; pseudouridine synthesis [GO:0001522]; ribosome biogenesis [GO:0042254]; RNA stabilization [GO:0043489]; rRNA processing [GO:0006364]; telomerase holoenzyme complex assembly [GO:1905323]; telomerase RNA stabilization [GO:0090669] GO:0000493; GO:0001522; GO:0003723; GO:0005634; GO:0005732; GO:0005737; GO:0006364; GO:0042254; GO:0042802; GO:0043489; GO:0051973; GO:0070034; GO:0090669; GO:1904358; GO:1905323 23646 XR_003827637.1 2 1 12 2 23 NA NA NA NA NA NA 23647 XM_044315101.1 61 10 33 33 46 NA NA NA NA NA NA 23648 XM_029330986.2 0 122 118 79 0 Q9WU81 1.81e-157 Glucose-6-phosphate exchanger SLC37A2 (Solute carrier family 37 member 2) (cAMP-inducible protein 2) Mus musculus (Mouse) carbohydrate transport [GO:0008643]; glucose-6-phosphate transport [GO:0015760]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerol-3-phosphate transmembrane transport [GO:0015794]; glycerophosphate shuttle [GO:0006127]; phosphate ion transmembrane transport [GO:0035435] GO:0005789; GO:0006072; GO:0006127; GO:0008643; GO:0015169; GO:0015760; GO:0015794; GO:0035435; GO:0061513 23649 XM_044312901.1 46 22 111 52 56 NA NA NA NA NA NA 23650 XM_029338436.2 2412 2997 1293 2041 1755 O35796 1.52e-23 Complement component 1 Q subcomponent-binding protein, mitochondrial (GC1q-R protein) (Glycoprotein gC1qBP) (C1qBP) Rattus norvegicus (Rat) apoptotic process [GO:0006915]; complement activation, classical pathway [GO:0006958]; cytosolic ribosome assembly [GO:0042256]; immune response [GO:0006955]; innate immune response [GO:0045087]; mRNA processing [GO:0006397]; negative regulation of defense response to virus [GO:0050687]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of MDA-5 signaling pathway [GO:0039534]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of RIG-I signaling pathway [GO:0039536]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type II interferon production [GO:0032689]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of mitochondrial translation [GO:0070131]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of trophoblast cell migration [GO:1901165]; regulation of complement activation [GO:0030449]; RNA splicing [GO:0008380] GO:0000122; GO:0001849; GO:0003714; GO:0003729; GO:0005080; GO:0005540; GO:0005615; GO:0005634; GO:0005730; GO:0005737; GO:0005739; GO:0005759; GO:0005829; GO:0005886; GO:0006397; GO:0006915; GO:0006955; GO:0006958; GO:0008380; GO:0009986; GO:0014065; GO:0016020; GO:0030449; GO:0030984; GO:0031690; GO:0032689; GO:0032695; GO:0039534; GO:0039536; GO:0042256; GO:0043065; GO:0045087; GO:0045785; GO:0048025; GO:0048786; GO:0050687; GO:0051897; GO:0070131; GO:0090023; GO:0097177; GO:0098978; GO:0098982; GO:1900026; GO:1901165; GO:2000510 23651 XM_044318156.1 617 290 422 212 77 P07314 7.83e-155 Glutathione hydrolase 1 proenzyme (EC 3.4.19.13) (Gamma-glutamyltransferase 1) (Gamma-glutamyltranspeptidase 1) (GGT 1) (EC 2.3.2.2) (Leukotriene-C4 hydrolase) (EC 3.4.19.14) (CD antigen CD224) [Cleaved into: Glutathione hydrolase 1 heavy chain; Glutathione hydrolase 1 light chain] Rattus norvegicus (Rat) aging [GO:0007568]; amino acid metabolic process [GO:0006520]; cellular response to oxidative stress [GO:0034599]; cysteine biosynthetic process [GO:0019344]; fatty acid metabolic process [GO:0006631]; glutamate metabolic process [GO:0006536]; glutathione biosynthetic process [GO:0006750]; glutathione catabolic process [GO:0006751]; hepatoblast differentiation [GO:0061017]; hepatocyte differentiation [GO:0070365]; leukotriene D4 biosynthetic process [GO:1901750]; leukotriene metabolic process [GO:0006691]; liver regeneration [GO:0097421]; peptide modification [GO:0031179]; proteolysis [GO:0006508]; regulation of immune system process [GO:0002682]; regulation of inflammatory response [GO:0050727]; response to alcohol [GO:0097305]; response to estradiol [GO:0032355]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]; spermatogenesis [GO:0007283]; zymogen activation [GO:0031638] GO:0000048; GO:0002682; GO:0002951; GO:0005615; GO:0005886; GO:0006508; GO:0006520; GO:0006536; GO:0006631; GO:0006691; GO:0006750; GO:0006751; GO:0007283; GO:0007568; GO:0016755; GO:0019344; GO:0031179; GO:0031638; GO:0031982; GO:0032355; GO:0032496; GO:0034599; GO:0034612; GO:0036374; GO:0050727; GO:0061017; GO:0070365; GO:0097305; GO:0097421; GO:0102953; GO:0103068; GO:1901750 23652 XM_044328388.1 19 21 13 55 10 Q8K2J9 3.56e-77 BTB/POZ domain-containing protein 6 Mus musculus (Mouse) neurogenesis [GO:0022008] GO:0005829; GO:0022008 23653 XM_044314584.1 23 74 37 0 35 NA NA NA NA NA NA 23654 XM_029356325.2 170 127 218 218 258 A0A1L8H0H2 3.18e-55 NA NA NA NA 23655 XM_029350384.2 0 0 0 71 138 Q99020 2.32e-49 Heterogeneous nuclear ribonucleoprotein A/B (hnRNP A/B) (CArG-binding factor-A) (CBF-A) Mus musculus (Mouse) epithelial to mesenchymal transition [GO:0001837]; mRNA modification [GO:0016556]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA demethylation [GO:1901537]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of cellular localization [GO:0060341]; regulation of gene expression [GO:0010468]; regulation of intracellular mRNA localization [GO:1904580] GO:0000122; GO:0001837; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0010468; GO:0016556; GO:0030425; GO:0044877; GO:0045293; GO:0045893; GO:0060341; GO:0071598; GO:0090575; GO:0099523; GO:1901537; GO:1904580; GO:1990124; GO:1990837; GO:1990904; GO:2000623 23656 XM_029358211.2 408 190 243 422 190 P35658 1.91e-78 Nuclear pore complex protein Nup214 (214 kDa nucleoporin) (Nucleoporin Nup214) (Protein CAN) Homo sapiens (Human) mitotic cell cycle [GO:0000278]; mRNA export from nucleus [GO:0006406]; nucleocytoplasmic transport [GO:0006913]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; regulation of cell cycle [GO:0051726]; regulation of nucleocytoplasmic transport [GO:0046822]; RNA export from nucleus [GO:0006405] GO:0000278; GO:0005049; GO:0005635; GO:0005643; GO:0005654; GO:0005829; GO:0006405; GO:0006406; GO:0006606; GO:0006611; GO:0006913; GO:0008139; GO:0017056; GO:0046822; GO:0051726; GO:1990876 23657 XM_029358211.2 408 190 243 422 190 P35658 3.22e-33 Nuclear pore complex protein Nup214 (214 kDa nucleoporin) (Nucleoporin Nup214) (Protein CAN) Homo sapiens (Human) mitotic cell cycle [GO:0000278]; mRNA export from nucleus [GO:0006406]; nucleocytoplasmic transport [GO:0006913]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; regulation of cell cycle [GO:0051726]; regulation of nucleocytoplasmic transport [GO:0046822]; RNA export from nucleus [GO:0006405] GO:0000278; GO:0005049; GO:0005635; GO:0005643; GO:0005654; GO:0005829; GO:0006405; GO:0006406; GO:0006606; GO:0006611; GO:0006913; GO:0008139; GO:0017056; GO:0046822; GO:0051726; GO:1990876 23658 XM_029349295.2 72 35 83 107 55 NA NA NA NA NA NA 23659 XM_029350909.2 9 12 8 25 10 NA NA NA NA NA NA 23660 XR_006392973.1 41 2 25 5 151 NA NA NA NA NA NA 23661 XM_044307543.1 165 576 341 927 246 Q8R418 2.36e-163 Endoribonuclease Dicer (EC 3.1.26.3) (Double-strand-specific ribonuclease mDCR-1) Mus musculus (Mouse) anatomical structure development [GO:0048856]; angiogenesis [GO:0001525]; apoptotic DNA fragmentation [GO:0006309]; branching morphogenesis of an epithelial tube [GO:0048754]; cardiac muscle cell development [GO:0055013]; cardiac neural crest cell development involved in outflow tract morphogenesis [GO:0061309]; cartilage development [GO:0051216]; cell population proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; defense response to virus [GO:0051607]; digestive tract development [GO:0048565]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; epidermis morphogenesis [GO:0048730]; ganglion development [GO:0061548]; gene expression [GO:0010467]; global gene silencing by mRNA cleavage [GO:0098795]; hair follicle cell proliferation [GO:0071335]; hair follicle development [GO:0001942]; hair follicle morphogenesis [GO:0031069]; inner ear receptor cell development [GO:0060119]; intestinal epithelial cell development [GO:0060576]; lung development [GO:0030324]; meiotic spindle organization [GO:0000212]; miRNA processing [GO:0035196]; mRNA stabilization [GO:0048255]; multicellular organism growth [GO:0035264]; myoblast differentiation involved in skeletal muscle regeneration [GO:0014835]; negative regulation of gene expression [GO:0010629]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of Schwann cell proliferation [GO:0010626]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of tumor necrosis factor production [GO:0032720]; nerve development [GO:0021675]; neuron projection morphogenesis [GO:0048812]; NIK/NF-kappaB signaling [GO:0038061]; olfactory bulb interneuron differentiation [GO:0021889]; pericentric heterochromatin formation [GO:0031508]; peripheral nervous system myelin formation [GO:0032290]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904906]; positive regulation of establishment of endothelial barrier [GO:1903142]; positive regulation of gene expression [GO:0010628]; positive regulation of hepatic stellate cell proliferation [GO:1904899]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of myelination [GO:0031643]; positive regulation of Schwann cell differentiation [GO:0014040]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; post-embryonic development [GO:0009791]; pre-miRNA processing [GO:0031054]; regulation of cell cycle [GO:0051726]; regulation of enamel mineralization [GO:0070173]; regulation of epithelial cell differentiation [GO:0030856]; regulation of gene expression [GO:0010468]; regulation of inflammatory response [GO:0050727]; regulation of miRNA metabolic process [GO:2000628]; regulation of muscle cell apoptotic process [GO:0010660]; regulation of myelination [GO:0031641]; regulation of neurogenesis [GO:0050767]; regulation of neuron differentiation [GO:0045664]; regulation of Notch signaling pathway [GO:0008593]; regulation of odontogenesis of dentin-containing tooth [GO:0042487]; regulation of oligodendrocyte differentiation [GO:0048713]; regulation of protein phosphorylation [GO:0001932]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of RNA metabolic process [GO:0051252]; regulation of stem cell differentiation [GO:2000736]; regulation of viral genome replication [GO:0045069]; reproductive structure development [GO:0048608]; RISC complex assembly [GO:0070922]; RNA phosphodiester bond hydrolysis [GO:0090501]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; RNA processing [GO:0006396]; RNA-mediated post-transcriptional gene silencing [GO:0035194]; rRNA processing [GO:0006364]; siRNA processing [GO:0030422]; spermatogonial cell division [GO:0007284]; spinal cord motor neuron differentiation [GO:0021522]; spindle assembly [GO:0051225]; spleen development [GO:0048536]; stem cell population maintenance [GO:0019827]; trophectodermal cell proliferation [GO:0001834]; zygote asymmetric cell division [GO:0010070] GO:0000122; GO:0000212; GO:0001525; GO:0001834; GO:0001932; GO:0001942; GO:0003677; GO:0003723; GO:0003725; GO:0004386; GO:0004521; GO:0004525; GO:0004530; GO:0005524; GO:0005634; GO:0005737; GO:0005783; GO:0005793; GO:0005829; GO:0006309; GO:0006364; GO:0006396; GO:0007284; GO:0008283; GO:0008593; GO:0009791; GO:0010070; GO:0010467; GO:0010468; GO:0010595; GO:0010626; GO:0010628; GO:0010629; GO:0010660; GO:0014040; GO:0014835; GO:0016442; GO:0019827; GO:0019904; GO:0021522; GO:0021675; GO:0021889; GO:0021987; GO:0030324; GO:0030326; GO:0030422; GO:0030424; GO:0030425; GO:0030426; GO:0030856; GO:0031054; GO:0031069; GO:0031508; GO:0031641; GO:0031643; GO:0032290; GO:0032720; GO:0032967; GO:0035116; GO:0035194; GO:0035196; GO:0035197; GO:0035198; GO:0035264; GO:0038061; GO:0042487; GO:0045069; GO:0045589; GO:0045664; GO:0045944; GO:0046872; GO:0048255; GO:0048471; GO:0048536; GO:0048565; GO:0048608; GO:0048713; GO:0048730; GO:0048754; GO:0048812; GO:0048856; GO:0050727; GO:0050767; GO:0051216; GO:0051225; GO:0051252; GO:0051607; GO:0051726; GO:0055013; GO:0060119; GO:0060253; GO:0060576; GO:0061309; GO:0061548; GO:0070062; GO:0070173; GO:0070578; GO:0070883; GO:0070922; GO:0071335; GO:0090501; GO:0090502; GO:0098795; GO:0098978; GO:0099092; GO:1903142; GO:1904899; GO:1904906; GO:1905564; GO:2000628; GO:2000630; GO:2000736 23662 XM_044307543.1 165 576 341 927 246 Q8R418 1.43e-66 Endoribonuclease Dicer (EC 3.1.26.3) (Double-strand-specific ribonuclease mDCR-1) Mus musculus (Mouse) anatomical structure development [GO:0048856]; angiogenesis [GO:0001525]; apoptotic DNA fragmentation [GO:0006309]; branching morphogenesis of an epithelial tube [GO:0048754]; cardiac muscle cell development [GO:0055013]; cardiac neural crest cell development involved in outflow tract morphogenesis [GO:0061309]; cartilage development [GO:0051216]; cell population proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; defense response to virus [GO:0051607]; digestive tract development [GO:0048565]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; epidermis morphogenesis [GO:0048730]; ganglion development [GO:0061548]; gene expression [GO:0010467]; global gene silencing by mRNA cleavage [GO:0098795]; hair follicle cell proliferation [GO:0071335]; hair follicle development [GO:0001942]; hair follicle morphogenesis [GO:0031069]; inner ear receptor cell development [GO:0060119]; intestinal epithelial cell development [GO:0060576]; lung development [GO:0030324]; meiotic spindle organization [GO:0000212]; miRNA processing [GO:0035196]; mRNA stabilization [GO:0048255]; multicellular organism growth [GO:0035264]; myoblast differentiation involved in skeletal muscle regeneration [GO:0014835]; negative regulation of gene expression [GO:0010629]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of Schwann cell proliferation [GO:0010626]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of tumor necrosis factor production [GO:0032720]; nerve development [GO:0021675]; neuron projection morphogenesis [GO:0048812]; NIK/NF-kappaB signaling [GO:0038061]; olfactory bulb interneuron differentiation [GO:0021889]; pericentric heterochromatin formation [GO:0031508]; peripheral nervous system myelin formation [GO:0032290]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904906]; positive regulation of establishment of endothelial barrier [GO:1903142]; positive regulation of gene expression [GO:0010628]; positive regulation of hepatic stellate cell proliferation [GO:1904899]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of myelination [GO:0031643]; positive regulation of Schwann cell differentiation [GO:0014040]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; post-embryonic development [GO:0009791]; pre-miRNA processing [GO:0031054]; regulation of cell cycle [GO:0051726]; regulation of enamel mineralization [GO:0070173]; regulation of epithelial cell differentiation [GO:0030856]; regulation of gene expression [GO:0010468]; regulation of inflammatory response [GO:0050727]; regulation of miRNA metabolic process [GO:2000628]; regulation of muscle cell apoptotic process [GO:0010660]; regulation of myelination [GO:0031641]; regulation of neurogenesis [GO:0050767]; regulation of neuron differentiation [GO:0045664]; regulation of Notch signaling pathway [GO:0008593]; regulation of odontogenesis of dentin-containing tooth [GO:0042487]; regulation of oligodendrocyte differentiation [GO:0048713]; regulation of protein phosphorylation [GO:0001932]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of RNA metabolic process [GO:0051252]; regulation of stem cell differentiation [GO:2000736]; regulation of viral genome replication [GO:0045069]; reproductive structure development [GO:0048608]; RISC complex assembly [GO:0070922]; RNA phosphodiester bond hydrolysis [GO:0090501]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; RNA processing [GO:0006396]; RNA-mediated post-transcriptional gene silencing [GO:0035194]; rRNA processing [GO:0006364]; siRNA processing [GO:0030422]; spermatogonial cell division [GO:0007284]; spinal cord motor neuron differentiation [GO:0021522]; spindle assembly [GO:0051225]; spleen development [GO:0048536]; stem cell population maintenance [GO:0019827]; trophectodermal cell proliferation [GO:0001834]; zygote asymmetric cell division [GO:0010070] GO:0000122; GO:0000212; GO:0001525; GO:0001834; GO:0001932; GO:0001942; GO:0003677; GO:0003723; GO:0003725; GO:0004386; GO:0004521; GO:0004525; GO:0004530; GO:0005524; GO:0005634; GO:0005737; GO:0005783; GO:0005793; GO:0005829; GO:0006309; GO:0006364; GO:0006396; GO:0007284; GO:0008283; GO:0008593; GO:0009791; GO:0010070; GO:0010467; GO:0010468; GO:0010595; GO:0010626; GO:0010628; GO:0010629; GO:0010660; GO:0014040; GO:0014835; GO:0016442; GO:0019827; GO:0019904; GO:0021522; GO:0021675; GO:0021889; GO:0021987; GO:0030324; GO:0030326; GO:0030422; GO:0030424; GO:0030425; GO:0030426; GO:0030856; GO:0031054; GO:0031069; GO:0031508; GO:0031641; GO:0031643; GO:0032290; GO:0032720; GO:0032967; GO:0035116; GO:0035194; GO:0035196; GO:0035197; GO:0035198; GO:0035264; GO:0038061; GO:0042487; GO:0045069; GO:0045589; GO:0045664; GO:0045944; GO:0046872; GO:0048255; GO:0048471; GO:0048536; GO:0048565; GO:0048608; GO:0048713; GO:0048730; GO:0048754; GO:0048812; GO:0048856; GO:0050727; GO:0050767; GO:0051216; GO:0051225; GO:0051252; GO:0051607; GO:0051726; GO:0055013; GO:0060119; GO:0060253; GO:0060576; GO:0061309; GO:0061548; GO:0070062; GO:0070173; GO:0070578; GO:0070883; GO:0070922; GO:0071335; GO:0090501; GO:0090502; GO:0098795; GO:0098978; GO:0099092; GO:1903142; GO:1904899; GO:1904906; GO:1905564; GO:2000628; GO:2000630; GO:2000736 23663 XM_044312971.1 34 5 116 112 219 NA NA NA NA NA NA 23664 XM_029339003.2 1167 1052 469 634 423 A6NJI9 1.83e-26 Leucine-rich repeat-containing protein 72 Homo sapiens (Human) NA NA 23665 XM_029346084.2 166 104 103 135 225 Q54TR1 6.41e-64 Counting factor associated protein D Dictyostelium discoideum (Social amoeba) immune response [GO:0006955]; negative regulation of asexual reproduction [GO:1903665]; positive regulation of chemorepellent activity [GO:1903669]; protein localization to plasma membrane [GO:0072659]; proteolysis involved in protein catabolic process [GO:0051603]; sorocarp morphogenesis [GO:0031288] GO:0004197; GO:0005576; GO:0005615; GO:0005764; GO:0006955; GO:0031288; GO:0031410; GO:0051603; GO:0072659; GO:1903665; GO:1903669 23666 XM_029340179.2 117 25 0 67 33 P08239 8.06e-167 Guanine nucleotide-binding protein G(o) subunit alpha (GTP-binding protein G39) Bos taurus (Bovine) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; dopamine receptor signaling pathway [GO:0007212] GO:0001664; GO:0003924; GO:0005525; GO:0005834; GO:0007188; GO:0007212; GO:0031683; GO:0031821; GO:0031852; GO:0046872; GO:0051430 23667 XM_044323288.1 0 30 0 29 7 Q5R5U3 6.51e-98 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 23668 XM_044323288.1 0 30 0 29 7 Q5R5U3 6.54e-97 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 23669 XM_044323288.1 0 30 0 29 7 Q5R5U3 1.9e-96 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 23670 XM_044323288.1 0 30 0 29 7 Q5R5U3 1.25e-95 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 23671 XM_044323288.1 0 30 0 29 7 Q5R5U3 1.79e-93 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 23672 XM_044323288.1 0 30 0 29 7 Q5R5U3 1.58e-90 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 23673 XM_044323288.1 0 30 0 29 7 Q5R5U3 6.44e-83 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 23674 XM_044323288.1 0 30 0 29 7 Q5R5U3 5.33e-80 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 23675 XM_044308605.1 1013 294 368 531 579 Q96AY4 1.06e-110 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23676 XM_044308605.1 1013 294 368 531 579 Q96AY4 1.39e-108 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23677 XM_044308605.1 1013 294 368 531 579 Q96AY4 1.41e-104 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23678 XM_044308605.1 1013 294 368 531 579 Q96AY4 2.42e-100 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23679 XM_044308605.1 1013 294 368 531 579 Q96AY4 5.51e-98 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23680 XM_044308605.1 1013 294 368 531 579 Q96AY4 2.38e-84 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23681 XM_044308605.1 1013 294 368 531 579 Q96AY4 3.54e-70 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23682 XM_044322153.1 178 125 265 142 250 NA NA NA NA NA NA 23683 XR_003825446.2 24 5 10 10 21 NA NA NA NA NA NA 23684 XM_029335813.2 55 25 4 64 0 NA NA NA NA NA NA 23685 XR_006395155.1 0 2 0 34 46 NA NA NA NA NA NA 23686 XM_029330498.2 0 0 12 0 17 NA NA NA NA NA NA 23687 XM_029337533.2 35 11 17 69 76 Q9YHV3 2.49e-33 Noggin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cartilage development [GO:0051216]; cloaca development [GO:0035844]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic viscerocranium morphogenesis [GO:0048703]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell differentiation [GO:0045596]; osteoblast differentiation [GO:0001649]; pronephros development [GO:0048793] GO:0001649; GO:0005615; GO:0007368; GO:0009953; GO:0030514; GO:0035844; GO:0045596; GO:0048703; GO:0048793; GO:0051216 23688 XM_044314236.1 1289 704 744 1940 1572 P04636 6.75e-119 Malate dehydrogenase, mitochondrial (EC 1.1.1.37) Rattus norvegicus (Rat) aerobic respiration [GO:0009060]; gluconeogenesis [GO:0006094]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099] GO:0005737; GO:0005739; GO:0005759; GO:0006094; GO:0006099; GO:0006107; GO:0006108; GO:0006734; GO:0009060; GO:0016020; GO:0016615; GO:0030060; GO:0042803; GO:0043621; GO:0046554 23689 XM_044328142.1 2525 1335 989 3616 5618 Q9UM47 7.01e-46 Neurogenic locus notch homolog protein 3 (Notch 3) [Cleaved into: Notch 3 extracellular truncation; Notch 3 intracellular domain] Homo sapiens (Human) artery morphogenesis [GO:0048844]; axon guidance [GO:0007411]; forebrain development [GO:0030900]; glomerular capillary formation [GO:0072104]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuroblast differentiation [GO:0014016]; neuron fate commitment [GO:0048663]; Notch signaling pathway [GO:0007219]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000122; GO:0000139; GO:0005509; GO:0005576; GO:0005654; GO:0005789; GO:0005829; GO:0005886; GO:0007219; GO:0007411; GO:0009986; GO:0014016; GO:0015629; GO:0019899; GO:0030900; GO:0038023; GO:0042802; GO:0043235; GO:0045296; GO:0045665; GO:0045944; GO:0048661; GO:0048663; GO:0048844; GO:0072104 23690 XM_044328142.1 2525 1335 989 3616 5618 Q9UM47 8.39e-32 Neurogenic locus notch homolog protein 3 (Notch 3) [Cleaved into: Notch 3 extracellular truncation; Notch 3 intracellular domain] Homo sapiens (Human) artery morphogenesis [GO:0048844]; axon guidance [GO:0007411]; forebrain development [GO:0030900]; glomerular capillary formation [GO:0072104]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuroblast differentiation [GO:0014016]; neuron fate commitment [GO:0048663]; Notch signaling pathway [GO:0007219]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000122; GO:0000139; GO:0005509; GO:0005576; GO:0005654; GO:0005789; GO:0005829; GO:0005886; GO:0007219; GO:0007411; GO:0009986; GO:0014016; GO:0015629; GO:0019899; GO:0030900; GO:0038023; GO:0042802; GO:0043235; GO:0045296; GO:0045665; GO:0045944; GO:0048661; GO:0048663; GO:0048844; GO:0072104 23691 XM_044328142.1 2525 1335 989 3616 5618 Q9UM47 8.18e-29 Neurogenic locus notch homolog protein 3 (Notch 3) [Cleaved into: Notch 3 extracellular truncation; Notch 3 intracellular domain] Homo sapiens (Human) artery morphogenesis [GO:0048844]; axon guidance [GO:0007411]; forebrain development [GO:0030900]; glomerular capillary formation [GO:0072104]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuroblast differentiation [GO:0014016]; neuron fate commitment [GO:0048663]; Notch signaling pathway [GO:0007219]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000122; GO:0000139; GO:0005509; GO:0005576; GO:0005654; GO:0005789; GO:0005829; GO:0005886; GO:0007219; GO:0007411; GO:0009986; GO:0014016; GO:0015629; GO:0019899; GO:0030900; GO:0038023; GO:0042802; GO:0043235; GO:0045296; GO:0045665; GO:0045944; GO:0048661; GO:0048663; GO:0048844; GO:0072104 23692 XM_044328142.1 2525 1335 989 3616 5618 Q9UM47 5.98e-22 Neurogenic locus notch homolog protein 3 (Notch 3) [Cleaved into: Notch 3 extracellular truncation; Notch 3 intracellular domain] Homo sapiens (Human) artery morphogenesis [GO:0048844]; axon guidance [GO:0007411]; forebrain development [GO:0030900]; glomerular capillary formation [GO:0072104]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuroblast differentiation [GO:0014016]; neuron fate commitment [GO:0048663]; Notch signaling pathway [GO:0007219]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000122; GO:0000139; GO:0005509; GO:0005576; GO:0005654; GO:0005789; GO:0005829; GO:0005886; GO:0007219; GO:0007411; GO:0009986; GO:0014016; GO:0015629; GO:0019899; GO:0030900; GO:0038023; GO:0042802; GO:0043235; GO:0045296; GO:0045665; GO:0045944; GO:0048661; GO:0048663; GO:0048844; GO:0072104 23693 XM_044328985.1 74 61 6 4 24 A2A6H3 2.14e-56 F-box only protein 47 Mus musculus (Mouse) NA NA 23694 XM_029334347.2 78 73 387 704 348 NA NA NA NA NA NA 23695 XM_044314938.1 188 52 49 82 31 NA NA NA NA NA NA 23696 XR_003825170.2 35 92 66 69 104 NA NA NA NA NA NA 23697 XM_044324276.1 21 0 0 0 0 P0C6B8 4e-128 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 23698 XM_044324276.1 21 0 0 0 0 P0C6B8 2.47e-120 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 23699 XM_044324276.1 21 0 0 0 0 P0C6B8 5.36e-104 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 23700 XM_044324276.1 21 0 0 0 0 P0C6B8 6.03e-103 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 23701 XM_044324276.1 21 0 0 0 0 P0C6B8 5.9e-65 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 23702 XM_044321897.1 0 18 0 21 0 Q9GZQ4 4.08e-22 Neuromedin-U receptor 2 (NMU-R2) (G-protein coupled receptor FM-4) (G-protein coupled receptor TGR-1) Homo sapiens (Human) arachidonic acid secretion [GO:0050482]; calcium ion transport [GO:0006816]; calcium-mediated signaling [GO:0019722]; cell-cell signaling [GO:0007267]; central nervous system development [GO:0007417]; feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; grooming behavior [GO:0007625]; inositol phosphate-mediated signaling [GO:0048016]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; reduction of food intake in response to dietary excess [GO:0002023]; regulation of sensory perception of pain [GO:0051930]; regulation of smooth muscle contraction [GO:0006940]; response to pain [GO:0048265] GO:0001607; GO:0002023; GO:0004930; GO:0005229; GO:0005525; GO:0005886; GO:0006816; GO:0006940; GO:0007186; GO:0007200; GO:0007204; GO:0007218; GO:0007267; GO:0007417; GO:0007625; GO:0007631; GO:0008188; GO:0016020; GO:0019722; GO:0042924; GO:0048016; GO:0048265; GO:0050482; GO:0051930 23703 XM_029339641.2 724 476 205 438 381 Q6IND7 3.19e-105 LRP2-binding protein Xenopus laevis (African clawed frog) NA GO:0005737 23704 XM_044315060.1 53 11 23 78 72 NA NA NA NA NA NA 23705 XM_029341770.2 820 469 334 642 556 A2RSY1 6.35e-154 KAT8 regulatory NSL complex subunit 3 (NSL complex protein NSL3) (Non-specific lethal 3 homolog) Mus musculus (Mouse) chromatin organization [GO:0006325]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of dosage compensation by inactivation of X chromosome [GO:1900095] GO:0000123; GO:0005654; GO:0006325; GO:0043231; GO:0043981; GO:0043982; GO:0043984; GO:0044545; GO:0045893; GO:0045944; GO:0051571; GO:1900095 23706 XM_029352350.2 3 2 2 6 24 NA NA NA NA NA NA 23707 XM_044324571.1 15 6 0 31 11 NA NA NA NA NA NA 23708 XR_003822965.2 115 80 54 113 98 NA NA NA NA NA NA 23709 XM_029355417.2 251 320 81 162 122 NA NA NA NA NA NA 23710 XM_044313832.1 0 0 145 0 179 NA NA NA NA NA NA 23711 XM_044317659.1 42 0 19 71 43 NA NA NA NA NA NA 23712 XM_044322947.1 878 1109 745 1265 1366 O14036 2.9e-50 Small nuclear ribonucleoprotein Sm D2 (Sm-D2) (Complexed with cdc5 protein 9) (snRNP core protein D2) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) mRNA 5'-splice site recognition [GO:0000395]; spliceosomal snRNP assembly [GO:0000387] GO:0000387; GO:0000395; GO:0000974; GO:0005634; GO:0005681; GO:0005682; GO:0005685; GO:0005686; GO:0005829; GO:0046540; GO:0071004; GO:0071011; GO:0071013; GO:0071014 23713 XM_044307774.1 0 0 15 23 13 P79385 9.82e-23 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (SED1) (Sperm surface protein SP47) (PP47) Sus scrofa (Pig) angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; single fertilization [GO:0007338] GO:0001525; GO:0002080; GO:0005576; GO:0007155; GO:0007338 23714 XM_029338522.2 907 835 423 695 604 NA NA NA NA NA NA 23715 XM_029354378.2 0 0 23 1 63 NA NA NA NA NA NA 23716 XM_029340100.2 20 62 18 49 36 NA NA NA NA NA NA 23717 XM_029345359.2 475 430 102 121 36 NA NA NA NA NA NA 23718 XM_044325293.1 230 29 64 184 255 NA NA NA NA NA NA 23719 XR_006395231.1 0 5 29 14 20 NA NA NA NA NA NA 23720 XM_044328188.1 195 29 25 24 23 NA NA NA NA NA NA 23721 XR_003826109.2 306 83 203 112 871 NA NA NA NA NA NA 23722 XM_029340436.2 158 43 67 137 56 NA NA NA NA NA NA 23723 XM_029324587.2 319 455 390 325 260 NA NA NA NA NA NA 23724 XM_029330608.2 2630 3183 2773 2429 1808 Q5PRC1 7.31e-48 LHFPL tetraspan subfamily member 6 protein Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0016020 23725 XM_029336282.2 4 0 12 4 8 E7F7V7 1.55e-30 Galanin receptor 2b Danio rerio (Zebrafish) (Brachydanio rerio) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; neuropeptide signaling pathway [GO:0007218] GO:0004966; GO:0005886; GO:0007188; GO:0007218; GO:0008528 23726 XM_029343389.2 34 30 22 36 31 NA NA NA NA NA NA 23727 XM_029325542.2 3696 2578 2138 3254 2486 Q8C0E2 2.71e-173 Vacuolar protein sorting-associated protein 26B (Vesicle protein sorting 26B) Mus musculus (Mouse) cellular response to type II interferon [GO:0071346]; intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147] GO:0005768; GO:0005769; GO:0005770; GO:0005829; GO:0006886; GO:0030904; GO:0042147; GO:0045335; GO:0071346 23728 XM_044307371.1 569 1034 663 475 583 Q969Q6 0 Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma (Protein phosphatase subunit G5PR) (Rhabdomyosarcoma antigen MU-RMS-40.6A/6C) Homo sapiens (Human) activation of protein kinase activity [GO:0032147]; B cell homeostasis [GO:0001782]; cortical cytoskeleton organization [GO:0030865]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of B cell differentiation [GO:0045579]; regulation of antimicrobial humoral response [GO:0002759]; regulation of dephosphorylation [GO:0035303]; regulation of mitochondrial depolarization [GO:0051900]; spleen development [GO:0048536]; T cell homeostasis [GO:0043029] GO:0000226; GO:0001782; GO:0002759; GO:0005654; GO:0005794; GO:0005813; GO:0005829; GO:0030865; GO:0032147; GO:0035303; GO:0043029; GO:0045579; GO:0046872; GO:0048536; GO:0051900 23729 XR_003824457.2 0 0 0 8 0 NA NA NA NA NA NA 23730 XM_044317794.1 394 150 169 290 344 Q6AI08 2.15e-155 HEAT repeat-containing protein 6 (Amplified in breast cancer protein 1) Homo sapiens (Human) NA GO:0003723 23731 XM_044317794.1 394 150 169 290 344 Q6AI08 2.11e-23 HEAT repeat-containing protein 6 (Amplified in breast cancer protein 1) Homo sapiens (Human) NA GO:0003723 23732 XM_029333535.2 1099 499 620 689 994 Q5U5C5 0 U4/U6 small nuclear ribonucleoprotein Prp31 (Pre-mRNA-processing factor 31) Xenopus laevis (African clawed frog) mRNA splicing, via spliceosome [GO:0000398]; spliceosomal tri-snRNP complex assembly [GO:0000244] GO:0000244; GO:0000398; GO:0005634; GO:0005690; GO:0015030; GO:0016607; GO:0030622; GO:0046540; GO:0071005; GO:0071339 23733 XM_029328273.2 0 0 160 300 133 Q5ZJP7 4.52e-28 BTB/POZ domain-containing protein KCTD7 Gallus gallus (Chicken) membrane hyperpolarization [GO:0060081]; positive regulation of transporter activity [GO:0032411]; protein homooligomerization [GO:0051260] GO:0005829; GO:0005886; GO:0032411; GO:0051260; GO:0060081 23734 XR_006396150.1 15 17 7 2 0 NA NA NA NA NA NA 23735 XR_006395629.1 149 283 265 99 49 NA NA NA NA NA NA 23736 XM_044322669.1 42 17 25 87 49 NA NA NA NA NA NA 23737 XM_029332895.2 152 110 115 157 143 NA NA NA NA NA NA 23738 XM_044312366.1 0 9 0 13 12 NA NA NA NA NA NA 23739 XM_044308140.1 1215 574 419 1067 760 Q8R5L3 0 Vam6/Vps39-like protein Mus musculus (Mouse) autophagosome-lysosome fusion [GO:0061909]; autophagy [GO:0006914]; endocytic recycling [GO:0032456]; endosomal vesicle fusion [GO:0034058]; endosome to lysosome transport [GO:0008333]; intracellular protein transport [GO:0006886]; late endosome to lysosome transport [GO:1902774] GO:0005737; GO:0005765; GO:0005770; GO:0006886; GO:0006914; GO:0008333; GO:0016020; GO:0030897; GO:0031902; GO:0032456; GO:0034058; GO:0061909; GO:1902501; GO:1902774 23740 XM_029356989.2 0 17 0 59 0 P30975 1.18e-21 Tachykinin-like peptides receptor 99D (Tachykinin-like receptor at 99D) (dTKR) Drosophila melanogaster (Fruit fly) detection of chemical stimulus involved in sensory perception of smell [GO:0050911]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; neuropeptide signaling pathway [GO:0007218]; olfactory behavior [GO:0042048]; positive regulation of sensory perception of pain [GO:1904058]; tachykinin receptor signaling pathway [GO:0007217] GO:0004995; GO:0005886; GO:0007186; GO:0007217; GO:0007218; GO:0008188; GO:0016020; GO:0042048; GO:0050805; GO:0050911; GO:1904058 23741 XM_029338748.2 3 7 3 23 5 F6QEU4 4.19e-84 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 23742 XM_029338748.2 3 7 3 23 5 F6QEU4 1.54e-26 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 23743 XM_044313911.1 1 353 5 306 45 NA NA NA NA NA NA 23744 XM_044319540.1 122 26 54 115 448 Q3LSS0 2.95e-151 CWF19-like protein 2 Danio rerio (Zebrafish) (Brachydanio rerio) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0071014 23745 XM_044319540.1 122 26 54 115 448 Q3LSS0 7.42e-21 CWF19-like protein 2 Danio rerio (Zebrafish) (Brachydanio rerio) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0071014 23746 XM_029338606.2 871 432 266 634 678 P57769 4.2e-41 Sorting nexin-16 Rattus norvegicus (Rat) early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; protein targeting to lysosome [GO:0006622] GO:0005764; GO:0005769; GO:0005770; GO:0005829; GO:0006622; GO:0008333; GO:0031313; GO:0031901; GO:0031902; GO:0035091; GO:0042802; GO:0045022 23747 XM_044324426.1 139 31 8 65 61 NA NA NA NA NA NA 23748 XM_044324495.1 174 161 19 5 10 NA NA NA NA NA NA 23749 XM_044310897.1 1 0 13 11 0 NA NA NA NA NA NA 23750 XM_044313341.1 4 0 5 0 14 NA NA NA NA NA NA 23751 XM_044312445.1 13 4 11 0 21 NA NA NA NA NA NA 23752 XR_006392587.1 17 0 8 19 0 NA NA NA NA NA NA 23753 XM_029340060.2 64 262 176 0 1 F1QB81 1.24e-21 NA NA NA NA 23754 XM_044310583.1 60 64 5 65 115 NA NA NA NA NA NA 23755 XR_006396878.1 31 10 14 5 21 NA NA NA NA NA NA 23756 XM_029342875.2 27 19 37 24 93 NA NA NA NA NA NA 23757 XR_006391543.1 29 5 1 0 4 NA NA NA NA NA NA 23758 XR_006395554.1 67 27 43 47 51 NA NA NA NA NA NA 23759 XM_029329723.2 516 843 389 828 389 NA NA NA NA NA NA 23760 XM_029338885.2 100 828 427 100 718 NA NA NA NA NA NA 23761 XM_044323217.1 0 20 24 13 41 NA NA NA NA NA NA 23762 XM_044310442.1 0 0 0 30 0 NA NA NA NA NA NA 23763 XM_044307533.1 195 131 176 249 520 NA NA NA NA NA NA 23764 XM_044323804.1 80 119 109 269 168 NA NA NA NA NA NA 23765 XM_044323975.1 540 210 163 626 899 Q810V0 2.88e-86 U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10) Mus musculus (Mouse) rRNA processing [GO:0006364] GO:0005694; GO:0005730; GO:0005732; GO:0006364; GO:0032040; GO:0034457 23766 XM_029331224.2 2685 1718 1783 2084 180 NA NA NA NA NA NA 23767 XR_006394594.1 23 0 0 9 10 NA NA NA NA NA NA 23768 XM_044315321.1 0 349 38 330 173 NA NA NA NA NA NA 23769 XR_006392215.1 0 0 16 15 0 NA NA NA NA NA NA 23770 XM_044315987.1 287 168 126 167 132 A3KN83 0 Protein strawberry notch homolog 1 (Monocyte protein 3) (MOP-3) Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355]; regulation of response to stimulus [GO:0048583] GO:0005634; GO:0006355; GO:0031490; GO:0042393; GO:0048583 23771 XM_044312021.1 0 5 7 1 45 NA NA NA NA NA NA 23772 XR_006397091.1 50 225 76 6 5 NA NA NA NA NA NA 23773 XR_003825111.2 33 0 3 0 32 NA NA NA NA NA NA 23774 XM_044308285.1 40 54 17 0 21 Q07598 0 Sterol carrier protein 2 (SCP-2) (Acetyl-CoA C-myristoyltransferase) (EC 2.3.1.155) (Non-specific lipid-transfer protein) (NSL-TP) (Propanoyl-CoA C-acyltransferase) (EC 2.3.1.176) (SCP-2/3-oxoacyl-CoA thiolase) (SCP-2/thiolase) (EC 2.3.1.16) (SCP-chi) (SCPX) (Sterol carrier protein X) (SCP-X) Gallus gallus (Chicken) bile acid metabolic process [GO:0008206]; fatty acid beta-oxidation [GO:0006635]; lipid transport [GO:0006869]; positive regulation of intracellular cholesterol transport [GO:0032385] GO:0003988; GO:0005737; GO:0005739; GO:0005777; GO:0005782; GO:0005783; GO:0006635; GO:0006869; GO:0008206; GO:0008289; GO:0032385; GO:0033814; GO:0050632; GO:0050633; GO:0120019; GO:0120020 23775 XM_029336776.2 142 0 0 144 174 Q29RU9 5.67e-78 Peroxisomal sarcosine oxidase (PSO) (EC 1.5.3.1) (EC 1.5.3.7) (L-pipecolate oxidase) (L-pipecolic acid oxidase) Bos taurus (Bovine) L-lysine catabolic process to acetyl-CoA via L-pipecolate [GO:0033514] GO:0005777; GO:0008115; GO:0033514; GO:0050031; GO:0050660 23776 XM_044327685.1 95 54 77 247 106 Q96AY4 2.89e-122 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23777 XM_044327685.1 95 54 77 247 106 Q96AY4 1.57e-93 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23778 XM_044327685.1 95 54 77 247 106 Q96AY4 3.55e-92 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23779 XM_044327685.1 95 54 77 247 106 Q96AY4 3.05e-91 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23780 XM_044327685.1 95 54 77 247 106 Q96AY4 3.94e-86 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23781 XM_044327685.1 95 54 77 247 106 Q96AY4 1.14e-82 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23782 XM_044327685.1 95 54 77 247 106 Q96AY4 1.08e-79 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23783 XM_029339333.2 0 0 0 0 15 NA NA NA NA NA NA 23784 XM_044320701.1 11 0 1 0 12 NA NA NA NA NA NA 23785 XR_006394655.1 66 34 18 56 21 Q5E9M5 7.18e-25 snRNA-activating protein complex subunit 3 (SNAPc subunit 3) (Small nuclear RNA-activating complex polypeptide 3) Bos taurus (Bovine) snRNA transcription by RNA polymerase II [GO:0042795]; snRNA transcription by RNA polymerase III [GO:0042796] GO:0001006; GO:0003681; GO:0005634; GO:0019185; GO:0042795; GO:0042796 23786 XR_006394067.1 131 19 51 8 12 NA NA NA NA NA NA 23787 XM_029334618.2 0 323 256 0 207 W8W138 2.02e-38 Beta-secretase (EC 3.4.23.-) Strongylocentrotus purpuratus (Purple sea urchin) amyloid-beta metabolic process [GO:0050435]; membrane protein ectodomain proteolysis [GO:0006509]; proteolysis [GO:0006508] GO:0004190; GO:0005768; GO:0005802; GO:0005886; GO:0006508; GO:0006509; GO:0050435 23788 XM_029334618.2 0 323 256 0 207 W8W138 2.02e-38 Beta-secretase (EC 3.4.23.-) Strongylocentrotus purpuratus (Purple sea urchin) amyloid-beta metabolic process [GO:0050435]; membrane protein ectodomain proteolysis [GO:0006509]; proteolysis [GO:0006508] GO:0004190; GO:0005768; GO:0005802; GO:0005886; GO:0006508; GO:0006509; GO:0050435 23789 XM_044324191.1 7 3 0 0 16 NA NA NA NA NA NA 23790 XM_044319392.1 25 23 0 20 18 Q96DM1 3.39e-79 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 23791 XM_044320938.1 0 0 0 0 583 Q6ZWJ1 8.99e-74 Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (STX4-interacting protein) (Synip) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; cellular response to type II interferon [GO:0071346]; insulin receptor signaling pathway [GO:0008286]; positive regulation of cell cycle G1/S phase transition [GO:1902808]; positive regulation of keratinocyte proliferation [GO:0010838]; protein stabilization [GO:0050821]; protein targeting [GO:0006605]; regulation of glucose transmembrane transport [GO:0010827]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072] GO:0006605; GO:0006974; GO:0008286; GO:0010827; GO:0010838; GO:0019905; GO:0031410; GO:0045335; GO:0050821; GO:0061178; GO:0070062; GO:0071346; GO:0098685; GO:0099072; GO:1902808 23792 XM_029325003.2 3618 4298 2883 3674 2641 NA NA NA NA NA NA 23793 XM_029344755.2 407 398 0 310 0 Q09225 1.62e-45 Nose resistant to fluoxetine protein 6 (Protein nrf-6) Caenorhabditis elegans lipid transport [GO:0006869] GO:0006869; GO:0008289; GO:0016020; GO:0016747 23794 XR_006396527.1 64 94 46 79 98 Q94K49 8.83e-37 Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1 (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) epigenetic regulation of gene expression [GO:0040029] GO:0003682; GO:0004518; GO:0005634; GO:0035098; GO:0035102; GO:0040029; GO:0046872 23795 XM_044326759.1 6 4 9 0 12 NA NA NA NA NA NA 23796 XM_029339231.2 113 70 115 127 46 NA NA NA NA NA NA 23797 XM_029355351.2 1561 737 739 1446 2663 NA NA NA NA NA NA 23798 XR_006391915.1 7 0 21 0 0 NA NA NA NA NA NA 23799 XR_006391843.1 8 0 0 0 2 NA NA NA NA NA NA 23800 XM_029337453.2 996 685 489 1135 636 Q96DY2 2.63e-52 Dynein regulatory complex protein 10 (IQ domain-containing protein D) Homo sapiens (Human) NA GO:0005737; GO:0031514; GO:0036064 23801 XM_044307603.1 13 14 4 9 7 NA NA NA NA NA NA 23802 XM_044308138.1 3095 3482 2332 2417 3925 Q9IA79 1.12e-68 Probable Bax inhibitor 1 (BI-1) (Testis-enhanced gene transcript protein homolog) (Transmembrane BAX inhibitor motif-containing protein 6) Paralichthys olivaceus (Bastard halibut) (Hippoglossus olivaceus) apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; response to unfolded protein [GO:0006986] GO:0005789; GO:0006915; GO:0006986; GO:0043066 23803 XM_044319088.1 42 13 13 0 0 NA NA NA NA NA NA 23804 XM_029343181.2 195 274 357 659 589 NA NA NA NA NA NA 23805 XM_044311834.1 959 195 404 465 393 Q5EA28 1.88e-88 CXXC-type zinc finger protein 1 (CpG-binding protein) (PHD finger and CXXC domain-containing protein 1) Bos taurus (Bovine) histone H3-K4 methylation [GO:0051568]; positive regulation of DNA-templated transcription [GO:0045893] GO:0005634; GO:0005829; GO:0008270; GO:0016363; GO:0016607; GO:0035064; GO:0045322; GO:0045893; GO:0048188; GO:0051568 23806 XR_003828467.2 14 18 17 19 4 NA NA NA NA NA NA 23807 XM_044307422.1 798 46 18 809 3 Q6TDP4 2.09e-36 Kelch-like protein 17 (Actinfilin) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; protein ubiquitination [GO:0016567]; regulation protein catabolic process at postsynapse [GO:0140252] GO:0005615; GO:0007420; GO:0014069; GO:0015629; GO:0016567; GO:0030036; GO:0031208; GO:0032839; GO:0043025; GO:0051015; GO:0060090; GO:0098978; GO:0140252 23808 XM_029329439.2 5815 3523 2851 3894 2570 Q15560 1.55e-87 Transcription elongation factor A protein 2 (Testis-specific S-II) (Transcription elongation factor S-II protein 2) (Transcription elongation factor TFIIS.l) Homo sapiens (Human) DNA-templated transcription [GO:0006351]; DNA-templated transcription elongation [GO:0006354]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription elongation [GO:0032784]; transcription elongation by RNA polymerase II promoter [GO:0006368] GO:0003677; GO:0005634; GO:0005654; GO:0005813; GO:0006351; GO:0006354; GO:0006368; GO:0008023; GO:0008270; GO:0032784; GO:0045944 23809 XM_029337447.2 0 38 0 0 0 Q9DCV4 1.52e-70 Regulator of microtubule dynamics protein 1 (RMD-1) (mRMD-1) (Microtubule-associated protein) (Protein FAM82B) Mus musculus (Mouse) NA GO:0005737; GO:0005739; GO:0005876; GO:0008017; GO:0097431 23810 XM_044328706.1 125 11 25 50 162 NA NA NA NA NA NA 23811 XM_029327078.2 161 159 144 94 61 NA NA NA NA NA NA 23812 XM_044314077.1 19 0 1 3 12 NA NA NA NA NA NA 23813 XM_029351311.2 1354 1112 1278 1380 674 P34147 3.52e-72 Rho-related protein racA Dictyostelium discoideum (Social amoeba) actin filament organization [GO:0007015]; cortical cytoskeleton organization [GO:0030865]; establishment or maintenance of cell polarity [GO:0007163]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; response to bacterium [GO:0009617]; small GTPase mediated signal transduction [GO:0007264] GO:0003924; GO:0005525; GO:0005856; GO:0005886; GO:0005938; GO:0007015; GO:0007163; GO:0007264; GO:0008360; GO:0009617; GO:0019901; GO:0030865; GO:0031410; GO:0032956; GO:0042995 23814 XM_044315183.1 0 7 2 0 19 NA NA NA NA NA NA 23815 XM_029330806.2 1773 1366 1029 1846 1685 Q68FI1 5.64e-35 Protein LSM14 homolog B-A (RNA-associated protein 46) (xRAP46) (RNA-associated protein 55B-A) (RAP55B-A) (xRAP55B) Xenopus laevis (African clawed frog) regulation of translation [GO:0006417] GO:0006417; GO:1990904 23816 XM_044322262.1 322 19 153 259 127 NA NA NA NA NA NA 23817 XM_044309628.1 75 2 16 19 107 NA NA NA NA NA NA 23818 XM_044313970.1 24 7 21 4 6 NA NA NA NA NA NA 23819 XM_044311785.1 141 249 102 215 306 NA NA NA NA NA NA 23820 XM_029343479.2 34200 26356 13636 29807 15608 P05689 9.64e-132 Cathepsin Z (EC 3.4.18.1) Bos taurus (Bovine) proteolysis involved in protein catabolic process [GO:0051603] GO:0004197; GO:0005615; GO:0005764; GO:0051603 23821 XM_044321428.1 21831 1 2674 129 806 NA NA NA NA NA NA 23822 XM_029331695.2 1796 4850 2271 2909 1253 Q7ZWG9 1.79e-74 Sigma non-opioid intracellular receptor 1 (Sigma 1-type opioid receptor) (Sigma1-receptor) (Sigma1R) Danio rerio (Zebrafish) (Brachydanio rerio) lipid transport [GO:0006869]; response to wounding [GO:0009611] GO:0005637; GO:0005640; GO:0005783; GO:0005789; GO:0006869; GO:0009611; GO:0016020; GO:0031410 23823 XR_006395862.1 83 38 28 74 185 Q6GX86 6.01e-34 Homologous recombination OB-fold protein Rattus norvegicus (Rat) cellular response to DNA damage stimulus [GO:0006974]; DNA synthesis involved in DNA repair [GO:0000731]; female gamete generation [GO:0007292]; interstrand cross-link repair [GO:0036297]; male gamete generation [GO:0048232]; recombinational repair [GO:0000725] GO:0000725; GO:0000731; GO:0003697; GO:0005634; GO:0006974; GO:0007292; GO:0036297; GO:0048232; GO:0090734 23824 XM_044313998.1 20 1 3 7 18 NA NA NA NA NA NA 23825 XM_029357988.2 759 527 410 473 640 NA NA NA NA NA NA 23826 XR_006398043.1 216 222 166 308 294 NA NA NA NA NA NA 23827 XM_044321317.1 108 287 289 184 260 NA NA NA NA NA NA 23828 XM_044316230.1 52 16 83 30 197 Q9VBW3 8.68e-56 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 23829 XM_029339599.2 925 825 438 908 605 Q9W676 2.05e-141 LIM domain-binding protein 2 (LDB-2) (Carboxyl-terminal LIM domain-binding protein 1) (CLIM-1) (LIM domain-binding factor CLIM1) (cLdb2) Gallus gallus (Chicken) negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000122; GO:0005634; GO:0005667; GO:0007399; GO:0030274; GO:0045944 23830 XR_006392930.1 41 2 25 5 151 NA NA NA NA NA NA 23831 XM_029335946.2 291 271 58 431 1108 Q12767 3.47e-137 Transmembrane protein 94 Homo sapiens (Human) NA GO:0016020 23832 XM_029335946.2 291 271 58 431 1108 Q12767 3.49e-31 Transmembrane protein 94 Homo sapiens (Human) NA GO:0016020 23833 XM_044320408.1 0 26 0 0 0 NA NA NA NA NA NA 23834 XM_029339296.2 24 18 0 0 0 NA NA NA NA NA NA 23835 XM_044326701.1 620 453 309 147 338 NA NA NA NA NA NA 23836 XM_044310673.1 24 0 16 2 3 NA NA NA NA NA NA 23837 XM_029333849.2 29437 28916 16228 21036 10555 P50616 3.68e-43 Protein Tob1 (Transducer of erbB-2 1) Homo sapiens (Human) negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060212]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of translation [GO:0017148]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; regulation of gene expression [GO:0010468]; regulation of SMAD protein signal transduction [GO:0060390] GO:0003714; GO:0005634; GO:0005737; GO:0008285; GO:0010468; GO:0017148; GO:0030014; GO:0030514; GO:0030971; GO:0045668; GO:0046332; GO:0060212; GO:0060213; GO:0060390; GO:1900153 23838 XM_044310741.1 0 7 0 0 0 NA NA NA NA NA NA 23839 XM_029323959.2 0 0 0 6 0 NA NA NA NA NA NA 23840 XM_044318631.1 8 0 77 84 562 Q9Z2E3 2.39e-54 Serine/threonine-protein kinase/endoribonuclease IRE2 (Endoplasmic reticulum-to-nucleus signaling 2) (Inositol-requiring protein 2) (Ire1-beta) (IRE1b) (mIre1) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)] Mus musculus (Mouse) apoptotic chromosome condensation [GO:0030263]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; IRE1-mediated unfolded protein response [GO:0036498]; mRNA processing [GO:0006397]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of JUN kinase activity [GO:0043507]; protein phosphorylation [GO:0006468]; regulation of DNA-templated transcription [GO:0006355]; response to endoplasmic reticulum stress [GO:0034976]; rRNA catabolic process [GO:0016075] GO:0000287; GO:0004519; GO:0004521; GO:0004674; GO:0005524; GO:0005783; GO:0005829; GO:0006355; GO:0006397; GO:0006468; GO:0016075; GO:0030263; GO:0034976; GO:0036498; GO:0043507; GO:0044322; GO:0045892; GO:0051082; GO:0070059; GO:0106310; GO:1990604 23841 XR_006392912.1 41 2 25 5 151 NA NA NA NA NA NA 23842 XM_044320313.1 344 174 468 279 1581 O57382 1.71e-32 Tolloid-like protein 2 (EC 3.4.24.-) (Metalloprotease xolloid) (Xenopus tolloid) Xenopus laevis (African clawed frog) cell differentiation [GO:0030154]; proteolysis [GO:0006508] GO:0004222; GO:0005509; GO:0005576; GO:0006508; GO:0008270; GO:0030154 23843 XM_029337754.2 1 0 0 9 0 NA NA NA NA NA NA 23844 XM_029341312.2 33 27 58 8 159 NA NA NA NA NA NA 23845 XM_044326198.1 0 7 68 5 137 NA NA NA NA NA NA 23846 XR_003826199.2 34 38 69 104 97 NA NA NA NA NA NA 23847 XM_044325730.1 1181 559 376 748 869 NA NA NA NA NA NA 23848 XM_029349320.2 305 120 204 545 343 A0A0G2JUG7 2.59e-83 IQ motif and SEC7 domain-containing protein 1 Rattus norvegicus (Rat) actin cytoskeleton organization [GO:0030036]; dendritic spine development [GO:0060996]; positive regulation of focal adhesion disassembly [GO:0120183]; positive regulation of keratinocyte migration [GO:0051549]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; regulation of ARF protein signal transduction [GO:0032012]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149] GO:0005085; GO:0005634; GO:0008021; GO:0008289; GO:0019901; GO:0030036; GO:0032012; GO:0051549; GO:0060996; GO:0098685; GO:0098794; GO:0098978; GO:0099092; GO:0099149; GO:0099170; GO:0120183 23849 XM_029353213.2 593 387 542 1138 857 A2AAY5 8.05e-52 SH3 and PX domain-containing protein 2B (Factor for adipocyte differentiation 49) (Tyrosine kinase substrate with four SH3 domains) Mus musculus (Mouse) adipose tissue development [GO:0060612]; bone development [GO:0060348]; cranial skeletal system development [GO:1904888]; extracellular matrix disassembly [GO:0022617]; eye development [GO:0001654]; heart development [GO:0007507]; osteoblast fate commitment [GO:0002051]; podosome assembly [GO:0071800]; positive regulation of adipose tissue development [GO:1904179]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of gene expression [GO:0010628]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of stress fiber assembly [GO:0051496]; protein localization to membrane [GO:0072657]; regulation of brood size [GO:0060378]; skeletal system development [GO:0001501]; skeletal system morphogenesis [GO:0048705]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801] GO:0001501; GO:0001654; GO:0002051; GO:0002102; GO:0005737; GO:0006801; GO:0007507; GO:0010314; GO:0010628; GO:0016176; GO:0022617; GO:0032266; GO:0040018; GO:0042169; GO:0042554; GO:0042995; GO:0045600; GO:0048705; GO:0051496; GO:0060348; GO:0060378; GO:0060612; GO:0070161; GO:0070273; GO:0071800; GO:0072657; GO:0080025; GO:1904179; GO:1904888 23850 XR_006393364.1 0 0 0 0 97 NA NA NA NA NA NA 23851 XM_029348700.2 28 3 0 33 0 Q9D787 0 RING-type E3 ubiquitin-protein ligase PPIL2 (EC 2.3.2.27) (CYC4) (Probable inactive peptidyl-prolyl cis-trans isomerase-like 2) (PPIase) Mus musculus (Mouse) protein folding [GO:0006457]; protein localization to plasma membrane [GO:0072659]; protein peptidyl-prolyl isomerization [GO:0000413]; protein polyubiquitination [GO:0000209] GO:0000209; GO:0000413; GO:0003755; GO:0004842; GO:0005634; GO:0005654; GO:0005737; GO:0005886; GO:0006457; GO:0034450; GO:0061630; GO:0071013; GO:0072659 23852 XR_006392255.1 72 63 159 195 192 NA NA NA NA NA NA 23853 XM_029333280.2 1584 2511 1009 2793 2221 NA NA NA NA NA NA 23854 XM_029352750.2 268 127 155 145 713 NA NA NA NA NA NA 23855 XM_029338167.2 600 373 299 882 51 O57472 2.3e-100 Chordin (Protein chordino) Danio rerio (Zebrafish) (Brachydanio rerio) anterior/posterior axis specification [GO:0009948]; caudal fin morphogenesis [GO:0035143]; determination of heart left/right asymmetry [GO:0061371]; determination of left/right symmetry [GO:0007368]; determination of ventral identity [GO:0048264]; dorsal convergence [GO:0060030]; dorsal/ventral pattern formation [GO:0009953]; embryonic heart tube morphogenesis [GO:0003143]; embryonic hemopoiesis [GO:0035162]; heart looping [GO:0001947]; Kupffer's vesicle development [GO:0070121]; negative regulation of BMP signaling pathway [GO:0030514]; otic placode formation [GO:0043049]; regulation of BMP signaling pathway involved in heart jogging [GO:2000223]; somitogenesis [GO:0001756]; specification of animal organ position [GO:0010159] GO:0001756; GO:0001947; GO:0003143; GO:0005615; GO:0007368; GO:0009948; GO:0009953; GO:0010159; GO:0030514; GO:0035143; GO:0035162; GO:0036122; GO:0043049; GO:0048264; GO:0060030; GO:0061371; GO:0070121; GO:2000223 23856 XM_044307823.1 182 84 213 262 554 NA NA NA NA NA NA 23857 XM_029356727.2 306 276 275 302 317 Q0V8A3 1.08e-80 Cytosolic arginine sensor for mTORC1 subunit 1 (GATS-like protein 3) Bos taurus (Bovine) cellular response to L-arginine [GO:1903577]; negative regulation of TORC1 signaling [GO:1904262]; regulation of intracellular signal transduction [GO:1902531] GO:0005829; GO:0034618; GO:0042802; GO:0061700; GO:0140311; GO:1902531; GO:1903577; GO:1904262 23858 XM_044323753.1 0 10 0 0 0 NA NA NA NA NA NA 23859 XM_029324184.2 19 92 58 0 54 Q3B8H4 7.69e-62 Rhombotin-1 (LIM domain only protein 1) (LMO-1) Xenopus laevis (African clawed frog) NA GO:0005634; GO:0046872 23860 XM_029357084.2 89 38 65 120 135 NA NA NA NA NA NA 23861 XM_044319646.1 357 315 335 660 757 O94762 1.21e-70 ATP-dependent DNA helicase Q5 (EC 3.6.4.12) (DNA helicase, RecQ-like type 5) (RecQ5) (RecQ protein-like 5) Homo sapiens (Human) cell division [GO:0051301]; cellular response to camptothecin [GO:0072757]; cellular response to ketone [GO:1901655]; cellular response to xenobiotic stimulus [GO:0071466]; chromosome separation [GO:0051304]; DNA duplex unwinding [GO:0032508]; DNA metabolic process [GO:0006259]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724]; mitotic cell cycle [GO:0000278]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; negative regulation of transcription elongation by RNA polymerase II [GO:0034244]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414] GO:0000278; GO:0000724; GO:0000993; GO:0003676; GO:0003678; GO:0005524; GO:0005634; GO:0005654; GO:0005694; GO:0005737; GO:0005829; GO:0006259; GO:0006260; GO:0006268; GO:0006281; GO:0006310; GO:0009378; GO:0016591; GO:0016887; GO:0032508; GO:0034244; GO:0042802; GO:0043138; GO:0051301; GO:0051304; GO:0071466; GO:0072757; GO:1901655; GO:1990414; GO:2000042 23862 XM_029346818.2 23 0 0 54 14 A7MB54 3.9e-25 H2.0-like homeobox protein (Homeobox protein HLX1) Bos taurus (Bovine) embryonic digestive tract morphogenesis [GO:0048557]; enteric nervous system development [GO:0048484]; epithelial cell proliferation [GO:0050673]; liver development [GO:0001889]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; organ growth [GO:0035265]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of organ growth [GO:0046622]; positive regulation of T-helper 1 cell differentiation [GO:0045627]; skeletal muscle tissue development [GO:0007519]; T-helper 1 cell differentiation [GO:0045063]; T-helper 2 cell differentiation [GO:0045064] GO:0000981; GO:0001889; GO:0005634; GO:0007519; GO:0035265; GO:0043565; GO:0045063; GO:0045064; GO:0045627; GO:0045629; GO:0046622; GO:0048484; GO:0048557; GO:0050673; GO:0050679 23863 XR_006397852.1 51 43 72 162 95 S8FIE4 4.25e-44 Laccase-1 (EC 1.10.3.2) (FpLCC1) Fomitopsis pinicola (strain FP-58527) (Brown rot fungus) NA GO:0005507; GO:0005576; GO:0016682 23864 XM_044327773.1 223 33 160 131 377 NA NA NA NA NA NA 23865 XM_029358525.2 2304 1469 1190 2855 2789 P21448 0 ATP-dependent translocase ABCB1 (ATP-binding cassette sub-family B member 1) (Multidrug resistance protein 1) (EC 7.6.2.2) (P-glycoprotein 1) (Phospholipid transporter ABCB1) (EC 7.6.2.1) (CD antigen CD243) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) phospholipid translocation [GO:0045332]; terpenoid transport [GO:0046865]; xenobiotic detoxification by transmembrane export across the plasma membrane [GO:1990961]; xenobiotic transport across blood-brain barrier [GO:1990962] GO:0005524; GO:0005737; GO:0008559; GO:0015562; GO:0016324; GO:0016887; GO:0045332; GO:0046581; GO:0046865; GO:0090554; GO:0090555; GO:0099038; GO:0140328; GO:1990961; GO:1990962 23866 XM_029358525.2 2304 1469 1190 2855 2789 P21448 1.47e-176 ATP-dependent translocase ABCB1 (ATP-binding cassette sub-family B member 1) (Multidrug resistance protein 1) (EC 7.6.2.2) (P-glycoprotein 1) (Phospholipid transporter ABCB1) (EC 7.6.2.1) (CD antigen CD243) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) phospholipid translocation [GO:0045332]; terpenoid transport [GO:0046865]; xenobiotic detoxification by transmembrane export across the plasma membrane [GO:1990961]; xenobiotic transport across blood-brain barrier [GO:1990962] GO:0005524; GO:0005737; GO:0008559; GO:0015562; GO:0016324; GO:0016887; GO:0045332; GO:0046581; GO:0046865; GO:0090554; GO:0090555; GO:0099038; GO:0140328; GO:1990961; GO:1990962 23867 XM_029358525.2 2304 1469 1190 2855 2789 P21448 1.85e-141 ATP-dependent translocase ABCB1 (ATP-binding cassette sub-family B member 1) (Multidrug resistance protein 1) (EC 7.6.2.2) (P-glycoprotein 1) (Phospholipid transporter ABCB1) (EC 7.6.2.1) (CD antigen CD243) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) phospholipid translocation [GO:0045332]; terpenoid transport [GO:0046865]; xenobiotic detoxification by transmembrane export across the plasma membrane [GO:1990961]; xenobiotic transport across blood-brain barrier [GO:1990962] GO:0005524; GO:0005737; GO:0008559; GO:0015562; GO:0016324; GO:0016887; GO:0045332; GO:0046581; GO:0046865; GO:0090554; GO:0090555; GO:0099038; GO:0140328; GO:1990961; GO:1990962 23868 XM_029358525.2 2304 1469 1190 2855 2789 P21448 2.74e-116 ATP-dependent translocase ABCB1 (ATP-binding cassette sub-family B member 1) (Multidrug resistance protein 1) (EC 7.6.2.2) (P-glycoprotein 1) (Phospholipid transporter ABCB1) (EC 7.6.2.1) (CD antigen CD243) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) phospholipid translocation [GO:0045332]; terpenoid transport [GO:0046865]; xenobiotic detoxification by transmembrane export across the plasma membrane [GO:1990961]; xenobiotic transport across blood-brain barrier [GO:1990962] GO:0005524; GO:0005737; GO:0008559; GO:0015562; GO:0016324; GO:0016887; GO:0045332; GO:0046581; GO:0046865; GO:0090554; GO:0090555; GO:0099038; GO:0140328; GO:1990961; GO:1990962 23869 XM_029348751.2 60 72 12 0 0 Q96CM3 2e-38 Pseudouridylate synthase RPUSD4, mitochondrial (EC 5.4.99.-) (RNA pseudouridylate synthase domain-containing protein 4) Homo sapiens (Human) enzyme-directed rRNA pseudouridine synthesis [GO:0000455]; mitochondrial tRNA pseudouridine synthesis [GO:0070902]; mRNA processing [GO:0006397]; mRNA pseudouridine synthesis [GO:1990481]; positive regulation of mitochondrial translation [GO:0070131]; RNA splicing [GO:0008380] GO:0000049; GO:0000455; GO:0003723; GO:0005654; GO:0005739; GO:0005759; GO:0006397; GO:0008380; GO:0009982; GO:0035770; GO:0070131; GO:0070902; GO:1990400; GO:1990481 23870 XM_044321843.1 0 0 0 39 0 O95260 7.28e-100 Arginyl-tRNA--protein transferase 1 (Arginyltransferase 1) (R-transferase 1) (EC 2.3.2.8) (Arginine-tRNA--protein transferase 1) Homo sapiens (Human) proteasomal protein catabolic process [GO:0010498]; protein arginylation [GO:0016598] GO:0004057; GO:0005634; GO:0005737; GO:0010498; GO:0016598 23871 XM_044320446.1 740 1065 434 941 307 Q95028 1.51e-149 L-lactate dehydrogenase (EC 1.1.1.27) Drosophila melanogaster (Fruit fly) carboxylic acid metabolic process [GO:0019752] GO:0004459; GO:0005737; GO:0019752 23872 XM_029337402.2 0 0 0 0 35 Q06441 9.76e-172 Thrombospondin-4 Xenopus laevis (African clawed frog) cell adhesion [GO:0007155]; positive regulation of cell division [GO:0051781]; response to unfolded protein [GO:0006986] GO:0005509; GO:0005615; GO:0005783; GO:0006986; GO:0007155; GO:0008083; GO:0016529; GO:0051781; GO:0062023 23873 XM_044323688.1 178 4 10 28 9 NA NA NA NA NA NA 23874 XM_044327608.1 61 315 50 169 96 NA NA NA NA NA NA 23875 XM_029328691.2 1031 691 518 788 598 Q96DH6 3.38e-79 RNA-binding protein Musashi homolog 2 (Musashi-2) Homo sapiens (Human) central nervous system development [GO:0007417]; regulation of translation [GO:0006417]; stem cell development [GO:0048864] GO:0003723; GO:0003729; GO:0005737; GO:0005829; GO:0005844; GO:0006417; GO:0007417; GO:0008266; GO:0042802; GO:0043231; GO:0048864 23876 XR_006396326.1 191 94 364 134 184 NA NA NA NA NA NA 23877 XM_029329758.2 1920 932 322 2004 2090 P42335 1.86e-122 Inositol-trisphosphate 3-kinase B (EC 2.7.1.127) (Inositol 1,4,5-trisphosphate 3-kinase B) (IP3 3-kinase B) (IP3K B) (InsP 3-kinase B) Rattus norvegicus (Rat) cell surface receptor signaling pathway [GO:0007166]; cellular response to calcium ion [GO:0071277]; common myeloid progenitor cell proliferation [GO:0035726]; inositol phosphate biosynthetic process [GO:0032958]; inositol trisphosphate metabolic process [GO:0032957]; MAPK cascade [GO:0000165]; myeloid cell homeostasis [GO:0002262]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of neutrophil apoptotic process [GO:0033030]; phosphatidylinositol phosphate biosynthetic process [GO:0046854]; phosphorylation [GO:0016310]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of Ras protein signal transduction [GO:0046579]; positive thymic T cell selection [GO:0045059]; regulation of protein phosphorylation [GO:0001932]; T cell differentiation [GO:0030217]; thymic T cell selection [GO:0045061] GO:0000165; GO:0000828; GO:0001932; GO:0002262; GO:0005516; GO:0005524; GO:0005634; GO:0005737; GO:0005783; GO:0005829; GO:0005856; GO:0007166; GO:0008440; GO:0016020; GO:0016301; GO:0016310; GO:0030217; GO:0032957; GO:0032958; GO:0033030; GO:0035726; GO:0045059; GO:0045061; GO:0045638; GO:0046579; GO:0046638; GO:0046854; GO:0071277 23878 XM_029354784.2 96 50 25 29 56 NA NA NA NA NA NA 23879 XM_044313649.1 40 21 9 13 74 NA NA NA NA NA NA 23880 XM_029342183.2 880 603 494 1147 916 Q96MW5 7.73e-179 Conserved oligomeric Golgi complex subunit 8 (COG complex subunit 8) (Component of oligomeric Golgi complex 8) Homo sapiens (Human) glycosylation [GO:0070085]; Golgi organization [GO:0007030]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein transport [GO:0015031]; retrograde transport, vesicle recycling within Golgi [GO:0000301] GO:0000139; GO:0000301; GO:0005794; GO:0006891; GO:0007030; GO:0015031; GO:0016020; GO:0017119; GO:0032588; GO:0070085 23881 XM_044315717.1 0 0 0 0 11 NA NA NA NA NA NA 23882 XM_044321485.1 1283 99 144 812 897 Q01804 5.51e-72 OTU domain-containing protein 4 (EC 3.4.19.12) (HIV-1-induced protein HIN-1) Homo sapiens (Human) innate immune response [GO:0045087]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; positive regulation of DNA demethylation [GO:1901537]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; regulation of protein K48-linked deubiquitination [GO:1903093] GO:0003723; GO:0004843; GO:0005634; GO:0005829; GO:0016579; GO:0034122; GO:0045087; GO:0060090; GO:0061578; GO:0070536; GO:0071108; GO:1901537; GO:1903093; GO:2000660 23883 XR_006393134.1 14 116 13 103 26 NA NA NA NA NA NA 23884 XM_029330751.2 891 1110 561 691 690 O14818 1.1e-142 Proteasome subunit alpha type-7 (Proteasome subunit RC6-1) (Proteasome subunit XAPC7) Homo sapiens (Human) proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] GO:0000502; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005839; GO:0010498; GO:0019773; GO:0042802; GO:0043161; GO:0070062; GO:0098794 23885 XM_044318625.1 0 0 1 0 11 P25304 3.56e-30 Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment (C90); Agrin C-terminal 22 kDa fragment (C22)] Rattus norvegicus (Rat) animal organ morphogenesis [GO:0009887]; cell differentiation [GO:0030154]; chemical synaptic transmission [GO:0007268]; motor neuron apoptotic process [GO:0097049]; negative regulation of P-type sodium:potassium-exchanging transporter activity [GO:1903407]; negative regulation of sodium ion export across plasma membrane [GO:1903277]; neuromuscular junction development [GO:0007528]; neurotransmitter receptor metabolic process [GO:0045213]; plasma membrane organization [GO:0007009]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of motor neuron apoptotic process [GO:2000673]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein binding [GO:0032092]; positive regulation of protein geranylgeranylation [GO:2000541]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of synaptic assembly at neuromuscular junction [GO:0045887]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor clustering [GO:0043113]; regulation of axon guidance [GO:1902667]; regulation of cardiac muscle cell membrane potential [GO:0086036]; regulation of cardiac muscle contraction [GO:0055117]; regulation of GTPase activity [GO:0043087]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of protein phosphorylation [GO:0001932]; regulation of synapse organization [GO:0050807]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse assembly [GO:0007416]; tissue development [GO:0009888] GO:0001932; GO:0001934; GO:0002162; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0007009; GO:0007268; GO:0007416; GO:0007528; GO:0009887; GO:0009888; GO:0009986; GO:0030154; GO:0030548; GO:0031012; GO:0032092; GO:0033691; GO:0035374; GO:0036122; GO:0042030; GO:0042383; GO:0043083; GO:0043087; GO:0043113; GO:0043395; GO:0043525; GO:0043547; GO:0044295; GO:0044325; GO:0045202; GO:0045213; GO:0045887; GO:0045944; GO:0050431; GO:0050731; GO:0050807; GO:0051491; GO:0055117; GO:0061098; GO:0062023; GO:0070507; GO:0071340; GO:0086036; GO:0097049; GO:0098978; GO:1902667; GO:1903277; GO:1903407; GO:2000541; GO:2000673 23886 XM_044318625.1 0 0 1 0 11 P25304 1.01e-24 Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment (C90); Agrin C-terminal 22 kDa fragment (C22)] Rattus norvegicus (Rat) animal organ morphogenesis [GO:0009887]; cell differentiation [GO:0030154]; chemical synaptic transmission [GO:0007268]; motor neuron apoptotic process [GO:0097049]; negative regulation of P-type sodium:potassium-exchanging transporter activity [GO:1903407]; negative regulation of sodium ion export across plasma membrane [GO:1903277]; neuromuscular junction development [GO:0007528]; neurotransmitter receptor metabolic process [GO:0045213]; plasma membrane organization [GO:0007009]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of motor neuron apoptotic process [GO:2000673]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein binding [GO:0032092]; positive regulation of protein geranylgeranylation [GO:2000541]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of synaptic assembly at neuromuscular junction [GO:0045887]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor clustering [GO:0043113]; regulation of axon guidance [GO:1902667]; regulation of cardiac muscle cell membrane potential [GO:0086036]; regulation of cardiac muscle contraction [GO:0055117]; regulation of GTPase activity [GO:0043087]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of protein phosphorylation [GO:0001932]; regulation of synapse organization [GO:0050807]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse assembly [GO:0007416]; tissue development [GO:0009888] GO:0001932; GO:0001934; GO:0002162; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0007009; GO:0007268; GO:0007416; GO:0007528; GO:0009887; GO:0009888; GO:0009986; GO:0030154; GO:0030548; GO:0031012; GO:0032092; GO:0033691; GO:0035374; GO:0036122; GO:0042030; GO:0042383; GO:0043083; GO:0043087; GO:0043113; GO:0043395; GO:0043525; GO:0043547; GO:0044295; GO:0044325; GO:0045202; GO:0045213; GO:0045887; GO:0045944; GO:0050431; GO:0050731; GO:0050807; GO:0051491; GO:0055117; GO:0061098; GO:0062023; GO:0070507; GO:0071340; GO:0086036; GO:0097049; GO:0098978; GO:1902667; GO:1903277; GO:1903407; GO:2000541; GO:2000673 23887 XM_044318625.1 0 0 1 0 11 P25304 4.28e-23 Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment (C90); Agrin C-terminal 22 kDa fragment (C22)] Rattus norvegicus (Rat) animal organ morphogenesis [GO:0009887]; cell differentiation [GO:0030154]; chemical synaptic transmission [GO:0007268]; motor neuron apoptotic process [GO:0097049]; negative regulation of P-type sodium:potassium-exchanging transporter activity [GO:1903407]; negative regulation of sodium ion export across plasma membrane [GO:1903277]; neuromuscular junction development [GO:0007528]; neurotransmitter receptor metabolic process [GO:0045213]; plasma membrane organization [GO:0007009]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of motor neuron apoptotic process [GO:2000673]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein binding [GO:0032092]; positive regulation of protein geranylgeranylation [GO:2000541]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of synaptic assembly at neuromuscular junction [GO:0045887]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor clustering [GO:0043113]; regulation of axon guidance [GO:1902667]; regulation of cardiac muscle cell membrane potential [GO:0086036]; regulation of cardiac muscle contraction [GO:0055117]; regulation of GTPase activity [GO:0043087]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of protein phosphorylation [GO:0001932]; regulation of synapse organization [GO:0050807]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse assembly [GO:0007416]; tissue development [GO:0009888] GO:0001932; GO:0001934; GO:0002162; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0007009; GO:0007268; GO:0007416; GO:0007528; GO:0009887; GO:0009888; GO:0009986; GO:0030154; GO:0030548; GO:0031012; GO:0032092; GO:0033691; GO:0035374; GO:0036122; GO:0042030; GO:0042383; GO:0043083; GO:0043087; GO:0043113; GO:0043395; GO:0043525; GO:0043547; GO:0044295; GO:0044325; GO:0045202; GO:0045213; GO:0045887; GO:0045944; GO:0050431; GO:0050731; GO:0050807; GO:0051491; GO:0055117; GO:0061098; GO:0062023; GO:0070507; GO:0071340; GO:0086036; GO:0097049; GO:0098978; GO:1902667; GO:1903277; GO:1903407; GO:2000541; GO:2000673 23888 XM_044314262.1 5 6 12 6 33 NA NA NA NA NA NA 23889 XM_044307560.1 9921 25583 3578 10016 3641 NA NA NA NA NA NA 23890 XM_044321427.1 803 296 68570 728 336 NA NA NA NA NA NA 23891 XM_029326698.2 102 118 41 5 139 NA NA NA NA NA NA 23892 XM_029343525.2 0 0 0 0 8 NA NA NA NA NA NA 23893 XM_044319536.1 49 0 0 4 0 NA NA NA NA NA NA 23894 XM_044318366.1 9 0 0 5 20 NA NA NA NA NA NA 23895 XM_044317556.1 21 1 5 4 20 NA NA NA NA NA NA 23896 XM_044328312.1 1 0 13 9 8 NA NA NA NA NA NA 23897 XM_044314709.1 10 0 28 3 0 NA NA NA NA NA NA 23898 XM_029352530.2 2008 1702 845 1465 1828 Q2T9V8 6.5e-72 D-aminoacyl-tRNA deacylase 1 (DTD) (EC 3.1.1.96) (DNA-unwinding element-binding protein B) (DUE-B) (Gly-tRNA(Ala) deacylase) Bos taurus (Bovine) DNA replication [GO:0006260]; tRNA metabolic process [GO:0006399] GO:0000049; GO:0003677; GO:0005634; GO:0005737; GO:0006260; GO:0006399; GO:0046872; GO:0051500 23899 XR_006394336.1 17 6 7 20 21 NA NA NA NA NA NA 23900 XM_044316691.1 51 3 34 99 202 C5G6D7 8.05e-46 Chondroitin sulfate ABC exolyase (EC 4.2.2.21) (Chondroitin ABC exoeliminase) (Chondroitin ABC lyase II) (Chondroitin sulfate ABC lyase II) (ChS ABC lyase II) (Chondroitinase ABC II) (cABC II) (Exochondroitinase ABC) Bacteroides thetaiotaomicron carbohydrate metabolic process [GO:0005975]; dermatan sulfate catabolic process [GO:0030209]; glycosaminoglycan catabolic process [GO:0006027] GO:0000287; GO:0005509; GO:0005576; GO:0005975; GO:0006027; GO:0030209; GO:0030246; GO:0034000; GO:0034001; GO:0042597 23901 XM_029330568.2 1179 1126 725 1483 819 A6NNM8 0 Tubulin polyglutamylase TTLL13 (EC 6.3.2.-) (Tubulin tyrosine ligase like 13) (Tubulin tyrosine ligase-like family member 13 pseudogene) (Tubulin--tyrosine ligase-like protein 13) Homo sapiens (Human) microtubule cytoskeleton organization [GO:0000226]; protein polyglutamylation [GO:0018095] GO:0000226; GO:0005524; GO:0005829; GO:0005874; GO:0005929; GO:0015631; GO:0018095; GO:0046872; GO:0070740 23902 XM_044326061.1 12 20 34 0 2 NA NA NA NA NA NA 23903 XM_044317745.1 0 0 0 37 0 Q8MJU1 6.44e-33 Caspase-3 (CASP-3) (EC 3.4.22.56) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12] Felis catus (Cat) (Felis silvestris catus) apoptotic process [GO:0006915]; erythrocyte differentiation [GO:0030218]; keratinocyte differentiation [GO:0030216]; neuron differentiation [GO:0030182]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; proteolysis [GO:0006508]; regulation of protein stability [GO:0031647] GO:0004175; GO:0005737; GO:0006508; GO:0006915; GO:0030182; GO:0030216; GO:0030218; GO:0031647; GO:0043065; GO:0097153; GO:0097199; GO:0097200; GO:1902004 23904 XM_029323845.2 43 7 26 30 119 Q566X8 3.16e-31 Diencephalon/mesencephalon homeobox protein 1-B Danio rerio (Zebrafish) (Brachydanio rerio) midbrain development [GO:0030901]; regulation of cell cycle [GO:0051726]; regulation of mitotic cell cycle [GO:0007346]; regulation of neural retina development [GO:0061074]; regulation of neurogenesis [GO:0050767]; regulation of transcription by RNA polymerase II [GO:0006357]; retina development in camera-type eye [GO:0060041] GO:0000977; GO:0000981; GO:0005634; GO:0006357; GO:0007346; GO:0030901; GO:0050767; GO:0051726; GO:0060041; GO:0061074 23905 XM_044314449.1 262 40 258 42 22 Q9H6E4 1.39e-37 Coiled-coil domain-containing protein 134 Homo sapiens (Human) angiogenesis [GO:0001525]; embryonic hemopoiesis [GO:0035162]; embryonic liver development [GO:1990402]; placenta development [GO:0001890]; regulation of ossification [GO:0030278]; ventricular system development [GO:0021591] GO:0001525; GO:0001890; GO:0005576; GO:0005634; GO:0005783; GO:0016020; GO:0021591; GO:0030278; GO:0035162; GO:1990402 23906 XM_044310063.1 0 0 92 0 0 O22943 1.45e-81 Probable glycosyltransferase STELLO1 (EC 2.4.-.-) Arabidopsis thaliana (Mouse-ear cress) plant-type cell wall cellulose biosynthetic process [GO:0052324]; regulation of plant-type cell wall cellulose biosynthetic process [GO:2001009] GO:0000139; GO:0005768; GO:0005794; GO:0005802; GO:0016757; GO:0042802; GO:0052324; GO:2001009 23907 XM_044327387.1 1516 160 1413 1374 1085 B2RY50 2.2e-166 Outer dynein arm-docking complex subunit 2 (Armadillo repeat-containing protein 4) Mus musculus (Mouse) cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; outer dynein arm assembly [GO:0036158]; regulation of cilium beat frequency [GO:0003356]; ventricular system development [GO:0021591] GO:0003341; GO:0003356; GO:0005930; GO:0007368; GO:0007507; GO:0021591; GO:0036158; GO:0097546 23908 XR_006392303.1 0 0 9 0 0 NA NA NA NA NA NA 23909 XM_029325219.2 0 10 4 0 802 Q54H46 1.83e-24 Probable serine/threonine-protein kinase drkA (EC 2.7.11.1) (Receptor-like kinase 1) (Receptor-like kinase A) (Vesicle-associated receptor tyrosine kinase-like protein 1) Dictyostelium discoideum (Social amoeba) receptor signaling pathway via STAT [GO:0097696]; signal transduction [GO:0007165] GO:0004672; GO:0004674; GO:0004713; GO:0005524; GO:0005737; GO:0007165; GO:0016020; GO:0097677; GO:0097696; GO:0106310 23910 XM_029348727.2 0 0 67 3 239 Q5U378 3.15e-96 Tubulin-specific chaperone E (Tubulin-folding cofactor E) Danio rerio (Zebrafish) (Brachydanio rerio) microtubule cytoskeleton organization [GO:0000226]; post-chaperonin tubulin folding pathway [GO:0007023]; tubulin complex assembly [GO:0007021] GO:0000226; GO:0005737; GO:0005856; GO:0007021; GO:0007023; GO:0043014 23911 XM_029334292.2 420 156 368 263 255 NA NA NA NA NA NA 23912 XM_044307989.1 208 64 194 227 340 Q09575 8.59e-39 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 23913 XM_029350216.2 188 33 186 423 285 Q9R0Z9 2.47e-160 Rho GTPase-activating protein 7 (Deleted in liver cancer 1 protein homolog) (DLC-1) (Rho-type GTPase-activating protein 7) (START domain-containing protein 12) (StARD12) (StAR-related lipid transfer protein 12) Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of phospholipase C activity [GO:0007202]; apoptotic process [GO:0006915]; cytoskeleton organization [GO:0007010]; focal adhesion assembly [GO:0048041]; forebrain development [GO:0030900]; heart morphogenesis [GO:0003007]; hindbrain morphogenesis [GO:0021575]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of stress fiber assembly [GO:0051497]; neural tube closure [GO:0001843]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; regulation of Rho protein signal transduction [GO:0035023]; signal transduction [GO:0007165] GO:0001725; GO:0001843; GO:0003007; GO:0005096; GO:0005634; GO:0005737; GO:0005829; GO:0005884; GO:0005901; GO:0005925; GO:0006915; GO:0006919; GO:0007010; GO:0007165; GO:0007202; GO:0008285; GO:0008289; GO:0008360; GO:0017166; GO:0021575; GO:0030036; GO:0030336; GO:0030864; GO:0030900; GO:0032587; GO:0032956; GO:0035023; GO:0035024; GO:0035307; GO:0042169; GO:0043274; GO:0045121; GO:0048041; GO:0051497; GO:0051895; GO:1900119 23914 XM_029350216.2 188 33 186 423 285 Q9R0Z9 5.02e-24 Rho GTPase-activating protein 7 (Deleted in liver cancer 1 protein homolog) (DLC-1) (Rho-type GTPase-activating protein 7) (START domain-containing protein 12) (StARD12) (StAR-related lipid transfer protein 12) Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of phospholipase C activity [GO:0007202]; apoptotic process [GO:0006915]; cytoskeleton organization [GO:0007010]; focal adhesion assembly [GO:0048041]; forebrain development [GO:0030900]; heart morphogenesis [GO:0003007]; hindbrain morphogenesis [GO:0021575]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of stress fiber assembly [GO:0051497]; neural tube closure [GO:0001843]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; regulation of Rho protein signal transduction [GO:0035023]; signal transduction [GO:0007165] GO:0001725; GO:0001843; GO:0003007; GO:0005096; GO:0005634; GO:0005737; GO:0005829; GO:0005884; GO:0005901; GO:0005925; GO:0006915; GO:0006919; GO:0007010; GO:0007165; GO:0007202; GO:0008285; GO:0008289; GO:0008360; GO:0017166; GO:0021575; GO:0030036; GO:0030336; GO:0030864; GO:0030900; GO:0032587; GO:0032956; GO:0035023; GO:0035024; GO:0035307; GO:0042169; GO:0043274; GO:0045121; GO:0048041; GO:0051497; GO:0051895; GO:1900119 23915 XR_006391923.1 2 0 7 7 0 NA NA NA NA NA NA 23916 XM_029336587.2 0 18 23 18 46 NA NA NA NA NA NA 23917 XM_029334395.2 421 166 141 208 298 Q90Z12 1.44e-26 Transcription factor HES-4-A (Hairy and enhancer of split 4-A) (Protein hairy-2) (Xhairy2) (Protein hairy-2a) (Xhairy2a) Xenopus laevis (African clawed frog) BMP signaling pathway [GO:0030509]; floor plate development [GO:0033504]; lens development in camera-type eye [GO:0002088]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural crest formation [GO:0014029]; prechordal plate formation [GO:0021501] GO:0000122; GO:0002088; GO:0005634; GO:0014029; GO:0021501; GO:0030509; GO:0033504; GO:0043066; GO:0043425; GO:0043565; GO:0045892; GO:0046983 23918 XM_044312003.1 3 0 26 0 34 NA NA NA NA NA NA 23919 XM_029339402.2 72 231 128 158 132 P57102 5.25e-22 Heart- and neural crest derivatives-expressed protein 2 (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND) Danio rerio (Zebrafish) (Brachydanio rerio) cardiac muscle cell differentiation [GO:0055007]; cardioblast differentiation [GO:0010002]; cardiocyte differentiation [GO:0035051]; cardiogenic plate morphogenesis [GO:0003142]; determination of intestine left/right asymmetry [GO:0071908]; developmental process [GO:0032502]; embryonic heart tube formation [GO:0003144]; embryonic pectoral fin morphogenesis [GO:0035118]; embryonic viscerocranium morphogenesis [GO:0048703]; heart contraction [GO:0060047]; heart development [GO:0007507]; heart looping [GO:0001947]; heart morphogenesis [GO:0003007]; noradrenergic neuron differentiation [GO:0003357]; polarized epithelial cell differentiation [GO:0030859]; proepicardium development [GO:0003342]; regulation of transcription by RNA polymerase II [GO:0006357]; sympathetic nervous system development [GO:0048485]; thyroid gland development [GO:0030878] GO:0000977; GO:0000981; GO:0001947; GO:0003007; GO:0003142; GO:0003144; GO:0003342; GO:0003357; GO:0005634; GO:0006357; GO:0007507; GO:0010002; GO:0030859; GO:0030878; GO:0032502; GO:0035051; GO:0035118; GO:0046983; GO:0048485; GO:0048703; GO:0055007; GO:0060047; GO:0071908 23920 XM_044326346.1 2750 1560 1019 1297 2126 R1CW23 1.58e-107 Dimethylsulfonioproprionate lyase 7 (DMSP lyase 7) (EC 4.4.1.3) (Dimethylpropiothetin dethiomethylase 7) Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi) NA GO:0047869 23921 XM_044314437.1 12 2 0 2 2 NA NA NA NA NA NA 23922 XM_029336219.2 23 41 22 49 0 NA NA NA NA NA NA 23923 XM_029356150.2 38 23 50 47 73 Q804S6 7.85e-28 Homeobox protein EMX1 (Empty spiracles homolog 1) (Empty spiracles-like protein 1) Danio rerio (Zebrafish) (Brachydanio rerio) brain development [GO:0007420]; central nervous system development [GO:0007417]; neuron differentiation [GO:0030182]; pronephric distal tubule development [GO:0035777]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0007417; GO:0007420; GO:0030182; GO:0035777 23924 XM_029338571.2 1319 1090 910 1355 1304 O43581 2.32e-93 Synaptotagmin-7 (IPCA-7) (Prostate cancer-associated protein 7) (Synaptotagmin VII) (SytVII) Homo sapiens (Human) calcium ion regulated lysosome exocytosis [GO:1990927]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; phagocytosis [GO:0006909]; phagosome-lysosome fusion [GO:0090385]; plasma membrane repair [GO:0001778]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; regulation of bone remodeling [GO:0046850]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of glucagon secretion [GO:0070092]; regulation of insulin secretion [GO:0050796]; regulation of phagocytosis [GO:0050764]; regulation of synaptic vesicle endocytosis [GO:1900242]; short-term synaptic potentiation [GO:1990926]; synaptic vesicle recycling [GO:0036465]; vesicle-mediated cholesterol transport [GO:0090119]; vesicle-mediated transport [GO:0016192] GO:0000149; GO:0001778; GO:0001786; GO:0005509; GO:0005516; GO:0005544; GO:0005546; GO:0005764; GO:0005765; GO:0005777; GO:0005778; GO:0005829; GO:0005886; GO:0006909; GO:0008021; GO:0014059; GO:0016192; GO:0017156; GO:0017158; GO:0019905; GO:0030276; GO:0030670; GO:0030672; GO:0031045; GO:0032009; GO:0036465; GO:0042734; GO:0042995; GO:0045956; GO:0046850; GO:0048791; GO:0050764; GO:0050796; GO:0070062; GO:0070092; GO:0070382; GO:0071277; GO:0090119; GO:0090385; GO:0098686; GO:1900242; GO:1990926; GO:1990927 23925 XM_044307564.1 46 96 56 50 98 Q8R496 4.31e-57 Speedy protein A (GS4) (Rapid inducer of G2/M progression in oocytes A) (RINGO A) (Speedy-1) (Spy1) Rattus norvegicus (Rat) cellular response to DNA damage stimulus [GO:0006974]; G1/S transition of mitotic cell cycle [GO:0000082]; male meiotic nuclear division [GO:0007140]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of protein kinase activity [GO:0045860] GO:0000082; GO:0005634; GO:0005654; GO:0006974; GO:0007140; GO:0008284; GO:0019901; GO:0030295; GO:0045737; GO:0045860 23926 XM_029346168.2 489 432 412 519 377 Q6P3N5 2.08e-50 Protein cornichon homolog 4 (CNIH-4) (Cornichon family AMPA receptor auxiliary protein 4) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; protein transport [GO:0015031] GO:0005783; GO:0005793; GO:0006888; GO:0015031; GO:0016020 23927 XM_029338044.2 41 22 52 22 2 NA NA NA NA NA NA 23928 XM_029351695.2 61 13 84 57 242 NA NA NA NA NA NA 23929 XM_029354550.2 12 4 0 0 0 NA NA NA NA NA NA 23930 XM_044315429.1 70 0 0 0 1 Q7RTR2 8.14e-58 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 23931 XM_044315429.1 70 0 0 0 1 Q7RTR2 1.18e-57 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 23932 XM_044315429.1 70 0 0 0 1 Q7RTR2 1.52e-44 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 23933 XM_044315429.1 70 0 0 0 1 Q7RTR2 1.46e-24 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 23934 XM_044315429.1 70 0 0 0 1 Q7RTR2 1.46e-24 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 23935 XM_044318296.1 2134 1125 861 1814 2252 Q14667 0 Bridge-like lipid transfer protein family member 2 (Antigen MLAA-22) (Breast cancer-overexpressed gene 1 protein) (Protein hobbit homolog) Homo sapiens (Human) NA GO:0005789; GO:0005886; GO:0031966; GO:0035091; GO:0140268 23936 XM_044311918.1 83 105 85 366 48 F1PZV2 2.95e-72 Major facilitator superfamily domain-containing protein 12 Canis lupus familiaris (Dog) (Canis familiaris) carbohydrate transport [GO:0008643]; cysteine transmembrane transport [GO:1903712]; melanin biosynthetic process [GO:0042438]; organic substance transport [GO:0071702]; pigment metabolic process involved in pigmentation [GO:0043474]; regulation of melanin biosynthetic process [GO:0048021] GO:0005764; GO:0005765; GO:0005886; GO:0008643; GO:0015293; GO:0033162; GO:0033229; GO:0042438; GO:0043474; GO:0048021; GO:0071702; GO:1903712 23937 XR_003825071.2 29 5 31 5 87 NA NA NA NA NA NA 23938 XM_044327048.1 11 0 0 0 20 NA NA NA NA NA NA 23939 XM_044318490.1 612 420 215 640 438 NA NA NA NA NA NA 23940 XM_029323835.2 670 599 351 750 400 O75366 0 Advillin (p92) Homo sapiens (Human) actin filament organization [GO:0007015]; actin filament severing [GO:0051014]; actin polymerization or depolymerization [GO:0008154]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]; nervous system development [GO:0007399]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of neuron projection development [GO:0010976]; regulation of diacylglycerol biosynthetic process [GO:1900480] GO:0003779; GO:0005546; GO:0005737; GO:0005884; GO:0005925; GO:0007015; GO:0007399; GO:0008154; GO:0010592; GO:0010976; GO:0015629; GO:0030027; GO:0030424; GO:0042995; GO:0043005; GO:0051014; GO:0051015; GO:0051016; GO:0060271; GO:0071933; GO:1900480 23941 XR_006392158.1 0 0 11 14 0 NA NA NA NA NA NA 23942 XM_029346324.2 124 66 37 205 433 O00305 1.92e-63 Voltage-dependent L-type calcium channel subunit beta-4 (CAB4) (Calcium channel voltage-dependent subunit beta 4) Homo sapiens (Human) adult walking behavior [GO:0007628]; cAMP metabolic process [GO:0046058]; cellular response to leukemia inhibitory factor [GO:1990830]; chemical synaptic transmission [GO:0007268]; detection of light stimulus involved in visual perception [GO:0050908]; gamma-aminobutyric acid secretion [GO:0014051]; gamma-aminobutyric acid signaling pathway [GO:0007214]; muscle cell development [GO:0055001]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; neuromuscular junction development [GO:0007528]; neuronal action potential propagation [GO:0019227]; Peyer's patch development [GO:0048541]; positive regulation of protein localization to nucleolus [GO:1904751]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; regulation of synaptic vesicle exocytosis [GO:2000300]; regulation of voltage-gated calcium channel activity [GO:1901385]; spleen development [GO:0048536]; synaptic transmission, glutamatergic [GO:0035249]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538] GO:0005730; GO:0005829; GO:0005886; GO:0005891; GO:0007214; GO:0007268; GO:0007528; GO:0007628; GO:0008285; GO:0009898; GO:0014051; GO:0016607; GO:0019227; GO:0019901; GO:0035249; GO:0045202; GO:0046058; GO:0048536; GO:0048538; GO:0048541; GO:0050852; GO:0050908; GO:0055001; GO:0098793; GO:0098978; GO:0099626; GO:1901385; GO:1901387; GO:1904751; GO:1990830; GO:2000134; GO:2000300 23943 XM_029346059.2 75 5 20 0 0 Q8CFK2 7.88e-151 Transcription factor IIIB 90 kDa subunit (TFIIIB90) (mTFIIIB90) (B-related factor 1) (BRF-1) Mus musculus (Mouse) DNA-templated transcription initiation [GO:0006352]; positive regulation of transcription by RNA polymerase III [GO:0045945]; regulation of mRNA stability [GO:0043488]; transcription by RNA polymerase III [GO:0006383]; transcription preinitiation complex assembly [GO:0070897] GO:0000126; GO:0000995; GO:0001006; GO:0005634; GO:0006352; GO:0006383; GO:0017025; GO:0043488; GO:0045945; GO:0046872; GO:0070897; GO:0097550 23944 XM_044308959.1 475 345 105 491 358 NA NA NA NA NA NA 23945 XM_029339642.2 223 124 182 204 292 Q9WYP5 8.82e-70 Myo-inositol 2-dehydrogenase (EC 1.1.1.18) Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) inositol metabolic process [GO:0006020]; NADPH regeneration [GO:0006740] GO:0000166; GO:0006020; GO:0006740; GO:0016491; GO:0050112 23946 XM_044311197.1 528 0 36 0 260 Q5TJ56 4.51e-44 Formin-F (Diaphanous-related formin dia1) Dictyostelium discoideum (Social amoeba) 'de novo' actin filament nucleation [GO:0070060]; actin filament polymerization [GO:0030041]; positive phototaxis [GO:0046956] GO:0005522; GO:0015629; GO:0030041; GO:0031143; GO:0031267; GO:0046956; GO:0051015; GO:0070060 23947 XM_044315995.1 35 12 12 12 41 NA NA NA NA NA NA 23948 XM_029323811.2 5896 3405 3883 2919 4122 Q14344 4.07e-159 Guanine nucleotide-binding protein subunit alpha-13 (G alpha-13) (G-protein subunit alpha-13) Homo sapiens (Human) activation of phospholipase D activity [GO:0031584]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; branching involved in blood vessel morphogenesis [GO:0001569]; cell differentiation [GO:0030154]; in utero embryonic development [GO:0001701]; multicellular organism aging [GO:0010259]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; negative regulation of vascular associated smooth muscle cell proliferation [GO:1904706]; platelet activation [GO:0030168]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; regulation of blood pressure [GO:0008217]; regulation of cell shape [GO:0008360]; regulation of fibroblast migration [GO:0010762]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; signal transduction [GO:0007165] GO:0001569; GO:0001664; GO:0001701; GO:0003924; GO:0005085; GO:0005525; GO:0005634; GO:0005737; GO:0005829; GO:0005834; GO:0005886; GO:0005925; GO:0007165; GO:0007188; GO:0007189; GO:0007204; GO:0007266; GO:0008217; GO:0008360; GO:0010259; GO:0010762; GO:0016020; GO:0030154; GO:0030168; GO:0031526; GO:0031584; GO:0031683; GO:0031752; GO:0042470; GO:0046872; GO:0051056; GO:0070062; GO:1904706; GO:1904753 23949 XM_044323450.1 20 13 3 16 13 Q8BHB0 6.71e-25 Nucleotide-binding oligomerization domain-containing protein 1 (Caspase recruitment domain-containing protein 4) Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cellular response to muramyl dipeptide [GO:0071225]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; ERK1 and ERK2 cascade [GO:0070371]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of cell death [GO:0010942]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of xenophagy [GO:1904417]; regulation of apoptotic process [GO:0042981]; stress-activated MAPK cascade [GO:0051403]; xenophagy [GO:0098792] GO:0002221; GO:0002606; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006915; GO:0006919; GO:0007249; GO:0007254; GO:0010942; GO:0016045; GO:0016323; GO:0016324; GO:0032731; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0035556; GO:0038187; GO:0042742; GO:0042802; GO:0042803; GO:0042981; GO:0043123; GO:0043280; GO:0044877; GO:0045087; GO:0045335; GO:0046330; GO:0050700; GO:0050830; GO:0051000; GO:0051092; GO:0051403; GO:0060907; GO:0070371; GO:0070374; GO:0071225; GO:0098792; GO:1901224; GO:1904417 23950 XM_044309489.1 71 49 0 96 0 NA NA NA NA NA NA 23951 XM_044315889.1 0 23 0 0 0 NA NA NA NA NA NA 23952 XM_044329193.1 124 11 68 23 193 NA NA NA NA NA NA 23953 XM_044314670.1 10 9 15 151 17 NA NA NA NA NA NA 23954 XM_044309947.1 0 23 0 75 0 P18433 3.68e-133 Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (EC 3.1.3.48) Homo sapiens (Human) insulin receptor signaling pathway [GO:0008286]; integrin-mediated signaling pathway [GO:0007229]; modulation of chemical synaptic transmission [GO:0050804]; protein dephosphorylation [GO:0006470]; protein phosphorylation [GO:0006468]; regulation of focal adhesion assembly [GO:0051893] GO:0004725; GO:0005001; GO:0005886; GO:0005925; GO:0006468; GO:0006470; GO:0007229; GO:0008286; GO:0016020; GO:0043235; GO:0050804; GO:0051893; GO:0070062; GO:0097060; GO:0098685 23955 XM_029324521.2 31 10 90 19 60 NA NA NA NA NA NA 23956 XR_006394811.1 0 0 0 0 15 NA NA NA NA NA NA 23957 XM_044322604.1 642 383 298 551 806 Q28141 0 ATP-dependent RNA helicase A (EC 3.6.4.13) (DEAH box protein 9) (Nuclear DNA helicase II) (NDH II) Bos taurus (Bovine) alternative mRNA splicing, via spliceosome [GO:0000380]; cellular response to exogenous dsRNA [GO:0071360]; cellular response to tumor necrosis factor [GO:0071356]; CRD-mediated mRNA stabilization [GO:0070934]; DNA duplex unwinding [GO:0032508]; DNA replication [GO:0006260]; DNA-templated transcription termination [GO:0006353]; DNA-templated viral transcription [GO:0039695]; G-quadruplex DNA unwinding [GO:0044806]; global gene silencing by mRNA cleavage [GO:0098795]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; mRNA transport [GO:0051028]; negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900152]; positive regulation of cytoplasmic translation [GO:2000767]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity [GO:2000373]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of polysome binding [GO:1905698]; positive regulation of response to cytokine stimulus [GO:0060760]; positive regulation of RNA export from nucleus [GO:0046833]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of viral transcription [GO:0050434]; positive regulation of viral translation [GO:1904973]; protein localization to cytoplasmic stress granule [GO:1903608]; regulation of cytoplasmic translation [GO:2000765]; regulation of mRNA processing [GO:0050684]; rhythmic process [GO:0048511]; RISC complex assembly [GO:0070922]; RNA secondary structure unwinding [GO:0010501] GO:0000380; GO:0000978; GO:0000993; GO:0001069; GO:0003677; GO:0003688; GO:0003690; GO:0003697; GO:0003713; GO:0003723; GO:0003724; GO:0003725; GO:0003727; GO:0003729; GO:0005524; GO:0005634; GO:0005654; GO:0005726; GO:0005730; GO:0005737; GO:0005813; GO:0005829; GO:0005844; GO:0006260; GO:0006353; GO:0006954; GO:0010501; GO:0015629; GO:0016442; GO:0016604; GO:0016887; GO:0017111; GO:0031490; GO:0032508; GO:0032727; GO:0032728; GO:0032755; GO:0032760; GO:0033679; GO:0034458; GO:0035197; GO:0035613; GO:0036464; GO:0039695; GO:0042788; GO:0043138; GO:0044806; GO:0045087; GO:0045142; GO:0045739; GO:0045740; GO:0045944; GO:0046833; GO:0046872; GO:0047429; GO:0048146; GO:0048511; GO:0050434; GO:0050684; GO:0051028; GO:0051092; GO:0060760; GO:0061629; GO:0061676; GO:0070063; GO:0070578; GO:0070922; GO:0070934; GO:0070937; GO:0071356; GO:0071360; GO:0097165; GO:0098795; GO:1900152; GO:1903608; GO:1904973; GO:1905172; GO:1905538; GO:1905698; GO:1990518; GO:1990825; GO:1990841; GO:1990904; GO:2000373; GO:2000637; GO:2000765; GO:2000767 23958 XR_003822850.2 123 0 106 0 0 NA NA NA NA NA NA 23959 XM_044317282.1 63 20 0 22 35 NA NA NA NA NA NA 23960 XM_029339813.2 19 31 0 168 220 NA NA NA NA NA NA 23961 XM_029333692.2 2052 1663 1206 2281 1781 Q5BLK4 3.49e-122 Terminal uridylyltransferase 7 (TUTase 7) (EC 2.7.7.52) (Zinc finger CCHC domain-containing protein 6) Mus musculus (Mouse) miRNA metabolic process [GO:0010586]; negative regulation of transposition, RNA-mediated [GO:0010526]; oocyte maturation [GO:0001556]; polyuridylation-dependent mRNA catabolic process [GO:1990074]; pre-miRNA processing [GO:0031054]; RNA 3' uridylation [GO:0071076]; RNA 3'-end processing [GO:0031123] GO:0001556; GO:0005654; GO:0005737; GO:0005829; GO:0008270; GO:0010526; GO:0010586; GO:0016779; GO:0031054; GO:0031123; GO:0035198; GO:0050265; GO:0070569; GO:0071076; GO:1990074 23962 XM_029333692.2 2052 1663 1206 2281 1781 Q5BLK4 1.47e-57 Terminal uridylyltransferase 7 (TUTase 7) (EC 2.7.7.52) (Zinc finger CCHC domain-containing protein 6) Mus musculus (Mouse) miRNA metabolic process [GO:0010586]; negative regulation of transposition, RNA-mediated [GO:0010526]; oocyte maturation [GO:0001556]; polyuridylation-dependent mRNA catabolic process [GO:1990074]; pre-miRNA processing [GO:0031054]; RNA 3' uridylation [GO:0071076]; RNA 3'-end processing [GO:0031123] GO:0001556; GO:0005654; GO:0005737; GO:0005829; GO:0008270; GO:0010526; GO:0010586; GO:0016779; GO:0031054; GO:0031123; GO:0035198; GO:0050265; GO:0070569; GO:0071076; GO:1990074 23963 XM_029333692.2 2052 1663 1206 2281 1781 Q5BLK4 1.33e-28 Terminal uridylyltransferase 7 (TUTase 7) (EC 2.7.7.52) (Zinc finger CCHC domain-containing protein 6) Mus musculus (Mouse) miRNA metabolic process [GO:0010586]; negative regulation of transposition, RNA-mediated [GO:0010526]; oocyte maturation [GO:0001556]; polyuridylation-dependent mRNA catabolic process [GO:1990074]; pre-miRNA processing [GO:0031054]; RNA 3' uridylation [GO:0071076]; RNA 3'-end processing [GO:0031123] GO:0001556; GO:0005654; GO:0005737; GO:0005829; GO:0008270; GO:0010526; GO:0010586; GO:0016779; GO:0031054; GO:0031123; GO:0035198; GO:0050265; GO:0070569; GO:0071076; GO:1990074 23964 XM_029334878.2 72 41 54 59 73 P00377 9.11e-47 Dihydrofolate reductase (EC 1.5.1.3) Sus scrofa (Pig) glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653] GO:0003729; GO:0004146; GO:0005737; GO:0005739; GO:0006545; GO:0006730; GO:0031427; GO:0046653; GO:0046654; GO:0050661 23965 XM_029339006.2 17 29 15 23 28 NA NA NA NA NA NA 23966 XM_044323661.1 12 0 10 5 2 NA NA NA NA NA NA 23967 XM_029346481.2 294 383 301 289 606 A2AG06 1.3e-25 Meiosis-specific coiled-coil domain-containing protein MEIOC (Meiosis-specific with coiled-coil domain protein) Mus musculus (Mouse) chromosome organization involved in meiotic cell cycle [GO:0070192]; double-strand break repair [GO:0006302]; female meiosis I [GO:0007144]; germline cell cycle switching, mitotic to meiotic cell cycle [GO:0051729]; male meiosis I [GO:0007141]; metaphase plate congression [GO:0051310]; mRNA stabilization [GO:0048255]; oocyte development [GO:0048599]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]; synaptonemal complex assembly [GO:0007130] GO:0005634; GO:0005737; GO:0006302; GO:0007130; GO:0007141; GO:0007144; GO:0007283; GO:0007286; GO:0048255; GO:0048599; GO:0051310; GO:0051729; GO:0070192 23968 XM_044316806.1 0 0 0 6 0 NA NA NA NA NA NA 23969 XM_044321391.1 14 5 14 3 26 M9NDE3 1.24e-31 Protein bark beetle (Protein anakonda) Drosophila melanogaster (Fruit fly) cell-cell junction maintenance [GO:0045217]; liquid clearance, open tracheal system [GO:0035002]; regulation of tube length, open tracheal system [GO:0035159]; response to endoplasmic reticulum stress [GO:0034976]; tricellular tight junction assembly [GO:1904274] GO:0005044; GO:0005912; GO:0005918; GO:0005923; GO:0016328; GO:0030246; GO:0034976; GO:0035002; GO:0035159; GO:0045217; GO:0061689; GO:1904274 23970 XM_044308799.1 21 0 0 0 0 NA NA NA NA NA NA 23971 XR_006394586.1 281 219 170 278 272 NA NA NA NA NA NA 23972 XM_029358597.2 601 643 317 505 247 Q5R6P5 6.2e-50 Mediator of RNA polymerase II transcription subunit 10 (Mediator complex subunit 10) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) regulation of transcription by RNA polymerase II [GO:0006357] GO:0003712; GO:0005654; GO:0006357; GO:0016592; GO:0070847 23973 XM_044311229.1 37 5 23 3 126 B3EWZ5 1.39e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 23974 XM_044311229.1 37 5 23 3 126 B3EWZ5 6.6e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 23975 XM_044311229.1 37 5 23 3 126 B3EWZ5 7.68e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 23976 XR_006395241.1 0 36 0 0 52 NA NA NA NA NA NA 23977 XM_029331985.2 137 36 46 91 28 A6QLE5 1.04e-26 NACHT, LRR and PYD domains-containing protein 3 (EC 3.6.4.-) Bos taurus (Bovine) detection of biotic stimulus [GO:0009595]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; NLRP3 inflammasome complex assembly [GO:0044546]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type 2 immune response [GO:0002830]; protein homooligomerization [GO:0051260]; regulation of inflammatory response [GO:0050727] GO:0002674; GO:0002830; GO:0005524; GO:0005576; GO:0005634; GO:0005737; GO:0005783; GO:0006954; GO:0009595; GO:0016020; GO:0016887; GO:0031021; GO:0032731; GO:0032753; GO:0035591; GO:0043280; GO:0043531; GO:0043565; GO:0044546; GO:0045087; GO:0045630; GO:0045944; GO:0050727; GO:0050729; GO:0051260; GO:0070273; GO:0072559; GO:0140297; GO:0140299; GO:1901223; GO:1901981; GO:2000553 23978 XR_006391985.1 26 9 44 26 108 NA NA NA NA NA NA 23979 XM_044323277.1 0 6 4 37 0 NA NA NA NA NA NA 23980 XM_029336961.2 112 78 52 119 87 NA NA NA NA NA NA 23981 XM_029342535.2 71 190 53 68 145 Q9EQD2 1.68e-33 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 23982 XM_029352971.2 0 75 63 0 0 NA NA NA NA NA NA 23983 XM_029327394.2 117 156 97 103 80 NA NA NA NA NA NA 23984 XR_006392840.1 46 75 0 129 32 NA NA NA NA NA NA 23985 XM_029351825.2 887 493 574 658 616 Q9NVM9 8.54e-180 Integrator complex subunit 13 (Cell cycle regulator Mat89Bb homolog) (Germ cell tumor 1) (Protein asunder homolog) (Sarcoma antigen NY-SAR-95) Homo sapiens (Human) cell division [GO:0051301]; centrosome localization [GO:0051642]; flagellated sperm motility [GO:0030317]; mitotic spindle organization [GO:0007052]; protein localization to nuclear envelope [GO:0090435]; regulation of fertilization [GO:0080154]; regulation of mitotic cell cycle [GO:0007346]; regulation of transcription elongation by RNA polymerase II [GO:0034243]; snRNA processing [GO:0016180] GO:0005634; GO:0005654; GO:0005737; GO:0007052; GO:0007346; GO:0016180; GO:0016604; GO:0030317; GO:0032039; GO:0034243; GO:0043231; GO:0051301; GO:0051642; GO:0080154; GO:0090435 23986 XM_029333556.2 198 28 58 9 17 P19801 4.59e-163 Amiloride-sensitive amine oxidase [copper-containing] (DAO) (Diamine oxidase) (EC 1.4.3.22) (Amiloride-binding protein 1) (Amine oxidase copper domain-containing protein 1) (Histaminase) (Kidney amine oxidase) (KAO) Homo sapiens (Human) amine metabolic process [GO:0009308]; cellular response to azide [GO:0097185]; cellular response to copper ion [GO:0071280]; cellular response to copper ion starvation [GO:0035874]; cellular response to heparin [GO:0071504]; cellular response to histamine [GO:0071420]; putrescine metabolic process [GO:0009445]; response to antibiotic [GO:0046677] GO:0005507; GO:0005509; GO:0005576; GO:0005615; GO:0005777; GO:0005886; GO:0005923; GO:0008131; GO:0008201; GO:0008270; GO:0009308; GO:0009445; GO:0035580; GO:0035874; GO:0042803; GO:0044877; GO:0046677; GO:0048038; GO:0052597; GO:0052598; GO:0052599; GO:0052600; GO:0070062; GO:0071280; GO:0071420; GO:0071504; GO:0097185 23987 XM_029328760.2 386 367 318 212 434 Q8BIY1 1.03e-85 G patch domain-containing protein 3 Mus musculus (Mouse) negative regulation of RIG-I signaling pathway [GO:0039536]; negative regulation of type I interferon production [GO:0032480]; positive regulation of DNA-templated transcription [GO:0045893] GO:0003676; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0032480; GO:0039536; GO:0045893 23988 XM_044322914.1 361 349 11 18 312 Q96P20 1.37e-38 NACHT, LRR and PYD domains-containing protein 3 (EC 3.6.4.-) (Angiotensin/vasopressin receptor AII/AVP-like) (Caterpiller protein 1.1) (CLR1.1) (Cold-induced autoinflammatory syndrome 1 protein) (Cryopyrin) (PYRIN-containing APAF1-like protein 1) Homo sapiens (Human) apoptotic process [GO:0006915]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to virus [GO:0098586]; defense response [GO:0006952]; detection of biotic stimulus [GO:0009595]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; NLRP3 inflammasome complex assembly [GO:0044546]; osmosensory signaling pathway [GO:0007231]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type 2 immune response [GO:0002830]; protein homooligomerization [GO:0051260]; pyroptosis [GO:0070269]; regulation of inflammatory response [GO:0050727]; signal transduction [GO:0007165] GO:0000139; GO:0002221; GO:0002674; GO:0002830; GO:0005524; GO:0005576; GO:0005634; GO:0005737; GO:0005739; GO:0005783; GO:0005815; GO:0005829; GO:0006915; GO:0006952; GO:0006954; GO:0007165; GO:0007231; GO:0009595; GO:0016020; GO:0016887; GO:0031021; GO:0032088; GO:0032691; GO:0032731; GO:0032753; GO:0035591; GO:0042802; GO:0042834; GO:0043280; GO:0043531; GO:0043565; GO:0044546; GO:0045087; GO:0045630; GO:0045944; GO:0050727; GO:0050728; GO:0050729; GO:0051092; GO:0051260; GO:0070269; GO:0070273; GO:0071222; GO:0072559; GO:0098586; GO:0140297; GO:0140299; GO:1901223; GO:1901981; GO:2000553 23989 XR_003825085.2 0 0 0 0 37 NA NA NA NA NA NA 23990 XR_006396194.1 153 54 34 64 51 Q8N865 1.83e-23 Uncharacterized protein C7orf31 Homo sapiens (Human) NA GO:0005737; GO:0005813 23991 XM_044322730.1 0 8 0 0 56 NA NA NA NA NA NA 23992 XR_006393883.1 30 142 65 215 59 NA NA NA NA NA NA 23993 XM_044307282.1 1571 743 626 1160 1253 Q5U534 6.56e-50 Mitochondrial amidoxime-reducing component 1 (mARC1) (EC 1.7.-.-) Xenopus laevis (African clawed frog) NA GO:0005741; GO:0016491; GO:0030151; GO:0030170 23994 XM_029332947.2 67 61 55 73 77 Q01097 5.78e-52 Glutamate receptor ionotropic, NMDA 2B (GluN2B) (Glutamate [NMDA] receptor subunit epsilon-2) (N-methyl D-aspartate receptor subtype 2B) (NMDAR2B) (NR2B) Mus musculus (Mouse) action potential [GO:0001508]; associative learning [GO:0008306]; behavioral fear response [GO:0001662]; behavioral response to pain [GO:0048266]; calcium ion transmembrane import into cytosol [GO:0097553]; calcium ion transport [GO:0006816]; cation transmembrane transport [GO:0098655]; cation transport [GO:0006812]; chemical synaptic transmission [GO:0007268]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; excitatory postsynaptic potential [GO:0060079]; fear response [GO:0042596]; in utero embryonic development [GO:0001701]; ionotropic glutamate receptor signaling pathway [GO:0035235]; learning [GO:0007612]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of dendritic spine maintenance [GO:1902951]; NMDA selective glutamate receptor signaling pathway [GO:0098989]; positive regulation of cell death [GO:0010942]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of glutamate secretion [GO:0014049]; positive regulation of neuron death [GO:1901216]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; protein heterotetramerization [GO:0051290]; receptor clustering [GO:0043113]; regulation of cation transmembrane transport [GO:1904062]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of MAPK cascade [GO:0043408]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of postsynaptic cytosolic calcium ion concentration [GO:0099566]; regulation of postsynaptic membrane potential [GO:0060078]; regulation of protein kinase A signaling [GO:0010738]; regulation of synaptic plasticity [GO:0048167]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to organonitrogen compound [GO:0010243]; rhythmic process [GO:0048511]; sensitization [GO:0046960]; sensory organ development [GO:0007423]; startle response [GO:0001964]; suckling behavior [GO:0001967] GO:0001508; GO:0001662; GO:0001666; GO:0001701; GO:0001964; GO:0001967; GO:0004970; GO:0004972; GO:0005102; GO:0005149; GO:0005234; GO:0005261; GO:0005262; GO:0005737; GO:0005764; GO:0005770; GO:0005789; GO:0005856; GO:0005886; GO:0006812; GO:0006816; GO:0007268; GO:0007423; GO:0007611; GO:0007612; GO:0007613; GO:0008013; GO:0008021; GO:0008270; GO:0008306; GO:0009986; GO:0010243; GO:0010738; GO:0010942; GO:0014049; GO:0014069; GO:0015276; GO:0016020; GO:0016594; GO:0016595; GO:0017146; GO:0022849; GO:0030018; GO:0030658; GO:0031749; GO:0035235; GO:0035255; GO:0036094; GO:0038023; GO:0042165; GO:0042596; GO:0042734; GO:0043005; GO:0043025; GO:0043083; GO:0043113; GO:0043195; GO:0043197; GO:0043408; GO:0044307; GO:0044877; GO:0045202; GO:0045211; GO:0045471; GO:0046960; GO:0048167; GO:0048168; GO:0048169; GO:0048266; GO:0048511; GO:0048787; GO:0050806; GO:0050839; GO:0050966; GO:0051290; GO:0051968; GO:0060078; GO:0060079; GO:0060291; GO:0097060; GO:0097110; GO:0097440; GO:0097553; GO:0098655; GO:0098686; GO:0098688; GO:0098794; GO:0098839; GO:0098978; GO:0098989; GO:0099507; GO:0099529; GO:0099566; GO:0099583; GO:1901216; GO:1901363; GO:1902951; GO:1904062; GO:1904315; GO:2000463; GO:2001056 23995 XR_006396278.1 389 145 132 881 168 P16157 6.98e-54 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 23996 XR_006396278.1 389 145 132 881 168 P16157 2.55e-52 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 23997 XR_006396278.1 389 145 132 881 168 P16157 4.08e-51 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 23998 XR_006396278.1 389 145 132 881 168 P16157 1.08e-44 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 23999 XR_006396278.1 389 145 132 881 168 P16157 1.53e-40 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 24000 XR_006396278.1 389 145 132 881 168 P16157 4.23e-28 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 24001 XR_006396278.1 389 145 132 881 168 P16157 1.29e-26 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 24002 XM_044318118.1 4 16 21 4 11 NA NA NA NA NA NA 24003 XM_044311633.1 163 150 151 118 140 NA NA NA NA NA NA 24004 XM_029323577.2 104 121 80 131 228 Q5XTS1 1.96e-139 Calcium-independent phospholipase A2-gamma (EC 3.1.1.-) (EC 3.1.1.5) (Group VIB calcium-independent phospholipase A2) (Intracellular membrane-associated calcium-independent phospholipase A2 gamma) (iPLA2-gamma) (Patatin-like phospholipase domain-containing protein 8) Oryctolagus cuniculus (Rabbit) arachidonic acid metabolic process [GO:0019369]; cardiolipin metabolic process [GO:0032048]; lipid catabolic process [GO:0016042]; lipid homeostasis [GO:0055088]; triglyceride homeostasis [GO:0070328] GO:0004622; GO:0005739; GO:0005777; GO:0005778; GO:0005789; GO:0008970; GO:0016020; GO:0016042; GO:0019369; GO:0031966; GO:0032048; GO:0047499; GO:0055088; GO:0070328; GO:0102545 24005 XR_006391986.1 12 0 0 0 16 NA NA NA NA NA NA 24006 XM_029344610.2 25 0 0 0 130 Q80U56 3.05e-57 Late secretory pathway protein AVL9 homolog Mus musculus (Mouse) cell migration [GO:0016477] GO:0005737; GO:0016020; GO:0016477; GO:0055037 24007 XM_029344610.2 25 0 0 0 130 Q80U56 9.87e-37 Late secretory pathway protein AVL9 homolog Mus musculus (Mouse) cell migration [GO:0016477] GO:0005737; GO:0016020; GO:0016477; GO:0055037 24008 XM_029344610.2 25 0 0 0 130 Q80U56 9.87e-37 Late secretory pathway protein AVL9 homolog Mus musculus (Mouse) cell migration [GO:0016477] GO:0005737; GO:0016020; GO:0016477; GO:0055037 24009 XM_044321964.1 96 89 17 59 54 Q9HF54 4.83e-41 GTP-binding protein RHO1 Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii) actin filament organization [GO:0007015]; cortical cytoskeleton organization [GO:0030865]; establishment or maintenance of cell polarity [GO:0007163]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; small GTPase mediated signal transduction [GO:0007264] GO:0003924; GO:0005525; GO:0005856; GO:0005886; GO:0005938; GO:0007015; GO:0007163; GO:0007264; GO:0008360; GO:0019901; GO:0030865; GO:0031410; GO:0032956; GO:0042995 24010 XM_044315471.1 88 254 65 20 378 Q9VBW3 5.77e-59 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 24011 XR_006393007.1 41 2 25 5 151 NA NA NA NA NA NA 24012 XM_044307976.1 23 35 5 19 7 NA NA NA NA NA NA 24013 XM_029346482.2 712 247 367 747 311 A2AG06 1.3e-25 Meiosis-specific coiled-coil domain-containing protein MEIOC (Meiosis-specific with coiled-coil domain protein) Mus musculus (Mouse) chromosome organization involved in meiotic cell cycle [GO:0070192]; double-strand break repair [GO:0006302]; female meiosis I [GO:0007144]; germline cell cycle switching, mitotic to meiotic cell cycle [GO:0051729]; male meiosis I [GO:0007141]; metaphase plate congression [GO:0051310]; mRNA stabilization [GO:0048255]; oocyte development [GO:0048599]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]; synaptonemal complex assembly [GO:0007130] GO:0005634; GO:0005737; GO:0006302; GO:0007130; GO:0007141; GO:0007144; GO:0007283; GO:0007286; GO:0048255; GO:0048599; GO:0051310; GO:0051729; GO:0070192 24014 XM_044324318.1 8 70 70 42 91 NA NA NA NA NA NA 24015 XM_044324622.1 58 0 81 13 350 Q8TE60 4.75e-129 A disintegrin and metalloproteinase with thrombospondin motifs 18 (ADAM-TS 18) (ADAM-TS18) (ADAMTS-18) (EC 3.4.24.-) Homo sapiens (Human) extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; negative regulation of platelet aggregation [GO:0090331]; proteolysis [GO:0006508] GO:0001654; GO:0004222; GO:0005576; GO:0006508; GO:0030198; GO:0031012; GO:0046872; GO:0090331 24016 XR_006391299.1 41 33 23 34 37 NA NA NA NA NA NA 24017 XM_044323505.1 84 45 195 89 515 NA NA NA NA NA NA 24018 XM_029330970.2 4 0 0 14 0 NA NA NA NA NA NA 24019 XM_029334554.2 132 68 54 295 141 O00602 2.85e-54 Ficolin-1 (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin-alpha) (M-ficolin) Homo sapiens (Human) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation, lectin pathway [GO:0001867]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of viral entry into host cell [GO:0046597]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of opsonization [GO:1903028]; protein localization to cell surface [GO:0034394]; proteolysis [GO:0006508]; recognition of apoptotic cell [GO:0043654] GO:0001664; GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005576; GO:0005581; GO:0005615; GO:0006508; GO:0007186; GO:0009897; GO:0030246; GO:0031232; GO:0032757; GO:0033691; GO:0034394; GO:0034774; GO:0038187; GO:0043654; GO:0046597; GO:0046872; GO:0062023; GO:0097367; GO:1903028; GO:1904813; GO:1905370 24020 XR_006393059.1 41 2 25 5 151 NA NA NA NA NA NA 24021 XM_029345369.2 1941 1379 948 801 1504 Q8TCT9 1.65e-160 Minor histocompatibility antigen H13 (EC 3.4.23.-) (Intramembrane protease 1) (IMP-1) (IMPAS-1) (hIMP1) (Presenilin-like protein 3) (Signal peptide peptidase) Homo sapiens (Human) in utero embryonic development [GO:0001701]; membrane protein proteolysis [GO:0033619]; membrane protein proteolysis involved in retrograde protein transport, ER to cytosol [GO:1904211]; regulation of heme oxygenase activity [GO:0061960]; signal peptide processing [GO:0006465] GO:0001701; GO:0005783; GO:0005789; GO:0005791; GO:0005886; GO:0006465; GO:0008233; GO:0009986; GO:0016020; GO:0031625; GO:0033619; GO:0036513; GO:0042500; GO:0042803; GO:0061960; GO:0098553; GO:0098554; GO:1904211 24022 XM_029350324.2 650 575 511 460 984 Q64559 1.93e-110 Cytosolic acyl coenzyme A thioester hydrolase (EC 3.1.2.2) (ACH1) (ACT) (Acyl-CoA thioesterase 7) (Brain acyl-CoA hydrolase) (BACH) (CTE-IIa) (CTE-IIb) (CTE-II) (LACH1) (Long chain acyl-CoA thioester hydrolase) (MTE-II) Rattus norvegicus (Rat) acyl-CoA metabolic process [GO:0006637]; coenzyme A biosynthetic process [GO:0015937]; fatty acid catabolic process [GO:0009062]; fatty acid metabolic process [GO:0006631]; long-chain fatty-acyl-CoA catabolic process [GO:0036116]; medium-chain fatty acid biosynthetic process [GO:0051792]; medium-chain fatty-acyl-CoA catabolic process [GO:0036114]; palmitic acid biosynthetic process [GO:1900535] GO:0000062; GO:0005654; GO:0005737; GO:0005759; GO:0005829; GO:0006631; GO:0006637; GO:0009062; GO:0015937; GO:0016290; GO:0036042; GO:0036114; GO:0036116; GO:0042802; GO:0042803; GO:0043005; GO:0043025; GO:0044297; GO:0047617; GO:0051792; GO:0102991; GO:1900535 24023 XM_029333897.2 0 108 74 0 502 Q9UHJ3 2.41e-57 Scm-like with four MBT domains protein 1 (hSFMBT) (Renal ubiquitous protein 1) Homo sapiens (Human) cell differentiation [GO:0030154]; chromatin organization [GO:0006325]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of muscle organ development [GO:0048635]; spermatogenesis [GO:0007283] GO:0003682; GO:0003714; GO:0005634; GO:0005654; GO:0006325; GO:0007283; GO:0030154; GO:0042393; GO:0045892; GO:0048635 24024 XM_029333897.2 0 108 74 0 502 Q9UHJ3 1.26e-32 Scm-like with four MBT domains protein 1 (hSFMBT) (Renal ubiquitous protein 1) Homo sapiens (Human) cell differentiation [GO:0030154]; chromatin organization [GO:0006325]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of muscle organ development [GO:0048635]; spermatogenesis [GO:0007283] GO:0003682; GO:0003714; GO:0005634; GO:0005654; GO:0006325; GO:0007283; GO:0030154; GO:0042393; GO:0045892; GO:0048635 24025 XR_006392907.1 41 2 25 5 151 NA NA NA NA NA NA 24026 XM_029335953.2 0 32 0 0 311 O14562 1.54e-85 Ubiquitin domain-containing protein UBFD1 (Ubiquitin-binding protein homolog) Homo sapiens (Human) NA GO:0003723; GO:0045296 24027 XM_044316755.1 1567 1859 1012 1613 1096 P56571 3.94e-113 ES1 protein homolog, mitochondrial Rattus norvegicus (Rat) NA GO:0005739 24028 XM_029333230.2 937 623 494 855 948 Q9W062 1.49e-74 Microfibrillar-associated protein 1 (Spliceosome B complex protein MFAP1) Drosophila melanogaster (Fruit fly) mRNA splicing, via spliceosome [GO:0000398]; regulation of G2/M transition of mitotic cell cycle [GO:0010389] GO:0000398; GO:0005684; GO:0010389; GO:0032991; GO:0071011; GO:0071013 24029 XM_029334031.2 0 38 0 0 51 Q9EQT3 4.08e-68 Rho-related GTP-binding protein RhoU (Rho GTPase-like protein ARHU) (Wnt-1 responsive Cdc42 homolog 1) (WRCH-1) Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; Cdc42 protein signal transduction [GO:0032488]; cytoskeleton organization [GO:0007010]; endocytosis [GO:0006897]; establishment or maintenance of cell polarity [GO:0007163]; G1/S transition of mitotic cell cycle [GO:0000082]; Rac protein signal transduction [GO:0016601]; regulation of cell shape [GO:0008360] GO:0000082; GO:0000139; GO:0002102; GO:0003924; GO:0005525; GO:0005886; GO:0005925; GO:0006897; GO:0007010; GO:0007163; GO:0008360; GO:0016601; GO:0030036; GO:0032488; GO:0042995; GO:0046872 24030 XM_029344935.2 177 233 159 234 124 Q54WT7 2.16e-38 Cystinosin homolog Dictyostelium discoideum (Social amoeba) L-cystine transport [GO:0015811] GO:0005765; GO:0005774; GO:0015184; GO:0015293; GO:0015811 24031 XM_044327397.1 1052 694 548 770 1061 Q58CV6 3.55e-109 Kelch domain-containing protein 3 Bos taurus (Bovine) meiotic cell cycle [GO:0051321]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567] GO:0005737; GO:0016567; GO:0031462; GO:0043161; GO:0051321; GO:1990756 24032 XM_029334263.2 47 17 59 41 79 P25931 4.27e-34 RYamide receptor (Neuropeptide Y-like receptor) (NPY-R) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218] GO:0001653; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0016020 24033 XR_006392213.1 41 8 22 46 27 NA NA NA NA NA NA 24034 XR_006395152.1 528 249 409 239 132 NA NA NA NA NA NA 24035 XR_006397983.1 0 0 0 0 9 NA NA NA NA NA NA 24036 XM_029328979.2 13 11 21 5 23 Q5R4R7 5.35e-21 PHD finger protein 24 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0046872 24037 XM_029342116.2 74 84 133 195 243 NA NA NA NA NA NA 24038 XM_029342788.2 2011 2606 1284 1634 1615 Q5RKS2 2.16e-25 Small integral membrane protein 7 Mus musculus (Mouse) NA GO:0016020 24039 XR_006393306.1 0 3 0 4 17 NA NA NA NA NA NA 24040 XM_044327554.1 3 4 22 13 145 NA NA NA NA NA NA 24041 XM_044319585.1 3 10 1 8 1 NA NA NA NA NA NA 24042 XR_006398183.1 123 67 59 134 46 NA NA NA NA NA NA 24043 XM_029350792.2 126 59 67 550 239 NA NA NA NA NA NA 24044 XM_029336069.2 43 15 38 79 12 NA NA NA NA NA NA 24045 XR_006393656.1 438 329 254 273 303 Q27889 1.21e-93 Serine/threonine-protein phosphatase 2B catalytic subunit 2 (EC 3.1.3.16) (Calmodulin-dependent calcineurin A2 subunit) Drosophila melanogaster (Fruit fly) calcineurin-mediated signaling [GO:0097720]; female meiotic nuclear division [GO:0007143]; meiotic cell cycle [GO:0051321]; protein dephosphorylation [GO:0006470]; regulation of embryonic development [GO:0045995]; sleep [GO:0030431]; wing disc development [GO:0035220] GO:0004722; GO:0004723; GO:0005516; GO:0005737; GO:0005955; GO:0006470; GO:0007143; GO:0017018; GO:0030431; GO:0033192; GO:0035220; GO:0045995; GO:0046872; GO:0051321; GO:0097720 24046 XM_044314644.1 173 69 121 92 70 P14381 3.02e-73 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 24047 XM_029342125.2 324 142 222 308 222 NA NA NA NA NA NA 24048 XM_029329521.2 444 324 128 286 86 O70521 8.42e-32 Regulator of G-protein signaling 19 (RGS19) (G-alpha-interacting protein) (GAIP) Rattus norvegicus (Rat) negative regulation of signal transduction [GO:0009968]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; response to ethanol [GO:0045471] GO:0000139; GO:0001965; GO:0005096; GO:0005737; GO:0005903; GO:0008277; GO:0009968; GO:0016020; GO:0030136; GO:0045121; GO:0045471 24049 XM_044309717.1 0 0 0 285 11 NA NA NA NA NA NA 24050 XM_044311433.1 9 4 13 8 68 NA NA NA NA NA NA 24051 XM_029328511.2 966 907 443 918 779 Q96RK4 0 Bardet-Biedl syndrome 4 protein Homo sapiens (Human) adult behavior [GO:0030534]; brain morphogenesis [GO:0048854]; centrosome cycle [GO:0007098]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; dendrite development [GO:0016358]; face development [GO:0060324]; fat cell differentiation [GO:0045444]; fat pad development [GO:0060613]; gene expression [GO:0010467]; heart looping [GO:0001947]; hippocampus development [GO:0021766]; intracellular transport [GO:0046907]; maintenance of protein location in nucleus [GO:0051457]; melanosome transport [GO:0032402]; microtubule anchoring at centrosome [GO:0034454]; microtubule cytoskeleton organization [GO:0000226]; mitotic cytokinesis [GO:0000281]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of appetite by leptin-mediated signaling pathway [GO:0038108]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of systemic arterial blood pressure [GO:0003085]; neural tube closure [GO:0001843]; neuron migration [GO:0001764]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; photoreceptor cell outer segment organization [GO:0035845]; positive regulation of cilium assembly [GO:0045724]; positive regulation of multicellular organism growth [GO:0040018]; protein localization to centrosome [GO:0071539]; protein localization to cilium [GO:0061512]; protein localization to organelle [GO:0033365]; protein localization to photoreceptor outer segment [GO:1903546]; protein transport [GO:0015031]; regulation of cilium beat frequency involved in ciliary motility [GO:0060296]; regulation of cytokinesis [GO:0032465]; regulation of lipid metabolic process [GO:0019216]; regulation of non-motile cilium assembly [GO:1902855]; regulation of stress fiber assembly [GO:0051492]; retina homeostasis [GO:0001895]; retinal rod cell development [GO:0046548]; sensory perception of smell [GO:0007608]; sensory processing [GO:0050893]; social behavior [GO:0035176]; spermatid development [GO:0007286]; striatum development [GO:0021756]; ventricular system development [GO:0021591]; visual perception [GO:0007601] GO:0000226; GO:0000242; GO:0000281; GO:0001750; GO:0001764; GO:0001843; GO:0001895; GO:0001917; GO:0001947; GO:0003085; GO:0005634; GO:0005813; GO:0005814; GO:0005829; GO:0005929; GO:0007098; GO:0007286; GO:0007601; GO:0007608; GO:0010467; GO:0010629; GO:0015031; GO:0016358; GO:0019216; GO:0021591; GO:0021756; GO:0021766; GO:0021987; GO:0030534; GO:0030674; GO:0030837; GO:0031514; GO:0032391; GO:0032402; GO:0032465; GO:0033365; GO:0034260; GO:0034451; GO:0034452; GO:0034454; GO:0034464; GO:0035176; GO:0035845; GO:0035869; GO:0036064; GO:0038108; GO:0040018; GO:0043014; GO:0045444; GO:0045494; GO:0045724; GO:0046548; GO:0046907; GO:0048487; GO:0048854; GO:0050893; GO:0051457; GO:0051492; GO:0060170; GO:0060271; GO:0060296; GO:0060324; GO:0060613; GO:0061512; GO:0061629; GO:0071539; GO:0097730; GO:1902855; GO:1903546; GO:1905515 24052 XM_044320528.1 50 64 64 16 16 NA NA NA NA NA NA 24053 XM_044316728.1 1281 1766 676 903 655 P02598 1.38e-33 Calmodulin (CaM) Tetrahymena pyriformis NA GO:0005509 24054 XR_006395889.1 75 75 163 166 285 NA NA NA NA NA NA 24055 XM_044313768.1 861 538 230 390 258 NA NA NA NA NA NA 24056 XM_029338849.2 1314 1240 687 1482 932 NA NA NA NA NA NA 24057 XM_029324816.2 580 179 76 283 233 Q9NVU0 2.14e-139 DNA-directed RNA polymerase III subunit RPC5 (RNA polymerase III subunit C5) (DNA-directed RNA polymerase III 80 kDa polypeptide) Homo sapiens (Human) defense response to virus [GO:0051607]; DNA-templated transcription [GO:0006351]; innate immune response [GO:0045087] GO:0005654; GO:0005666; GO:0005829; GO:0006351; GO:0045087; GO:0051607 24058 XM_044327619.1 297 288 114 152 96 NA NA NA NA NA NA 24059 XM_044308181.1 239 0 49 134 407 Q9V9A7 3.41e-165 Probable methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCase subunit beta) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 2) (3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta) Drosophila melanogaster (Fruit fly) coenzyme A metabolic process [GO:0015936]; leucine catabolic process [GO:0006552]; regulation of eclosion [GO:0007563] GO:0004485; GO:0005524; GO:0005739; GO:0005759; GO:0006552; GO:0007563; GO:0015936; GO:1905202 24060 XM_044318008.1 21 1 7 120 25 NA NA NA NA NA NA 24061 XM_029339380.2 105 0 41 0 377 NA NA NA NA NA NA 24062 XM_029333297.2 1124 4 652 347 1332 Q96AY4 5.59e-138 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24063 XM_029333297.2 1124 4 652 347 1332 Q96AY4 5.9e-130 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24064 XM_029333297.2 1124 4 652 347 1332 Q96AY4 1.18e-106 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24065 XM_029333297.2 1124 4 652 347 1332 Q96AY4 1.63e-69 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24066 XM_029333297.2 1124 4 652 347 1332 Q96AY4 1.33e-37 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24067 XM_029333297.2 1124 4 652 347 1332 Q96AY4 7.04e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24068 XM_029343557.2 250 239 118 281 284 Q8C8M1 2.86e-35 SIN3-HDAC complex-associated factor (Protein FAM60A) (Tera protein) Mus musculus (Mouse) negative regulation of cell differentiation [GO:0045596]; negative regulation of cell migration [GO:0030336]; negative regulation of stem cell population maintenance [GO:1902455]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of stem cell population maintenance [GO:1902459] GO:0000122; GO:0005634; GO:0008284; GO:0016580; GO:0030336; GO:0030512; GO:0045596; GO:1902455; GO:1902459 24069 XM_029358723.2 20 17 28 23 13 NA NA NA NA NA NA 24070 XM_044326286.1 273 102 54 444 107 Q5VU97 5.74e-151 VWFA and cache domain-containing protein 1 (Cache domain-containing protein 1) Homo sapiens (Human) NA GO:0005245; GO:0005891 24071 XM_029329143.2 270 107 34 271 0 Q12802 8.63e-82 A-kinase anchor protein 13 (AKAP-13) (AKAP-Lbc) (Breast cancer nuclear receptor-binding auxiliary protein) (Guanine nucleotide exchange factor Lbc) (Human thyroid-anchoring protein 31) (Lymphoid blast crisis oncogene) (LBC oncogene) (Non-oncogenic Rho GTPase-specific GTP exchange factor) (Protein kinase A-anchoring protein 13) (PRKA13) (p47) Homo sapiens (Human) adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process [GO:0086023]; adrenergic receptor signaling pathway [GO:0071875]; bone development [GO:0060348]; cardiac muscle cell differentiation [GO:0055007]; cell growth involved in cardiac muscle cell development [GO:0061049]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; nuclear export [GO:0051168]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Rho protein signal transduction [GO:0035025]; regulation of Rho protein signal transduction [GO:0035023]; regulation of sarcomere organization [GO:0060297]; regulation of small GTPase mediated signal transduction [GO:0051056] GO:0005078; GO:0005085; GO:0005634; GO:0005829; GO:0005938; GO:0007186; GO:0007507; GO:0016020; GO:0031267; GO:0035023; GO:0035025; GO:0043123; GO:0043406; GO:0046872; GO:0048471; GO:0051018; GO:0051056; GO:0051168; GO:0055007; GO:0060090; GO:0060297; GO:0060348; GO:0061049; GO:0071875; GO:0086023 24072 XM_044313112.1 120 74 53 95 91 Q6P9S1 5.79e-25 ATM interactor (ATM/ATR-substrate CHK2-interacting zinc finger protein) (ASCIZ) Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; motile cilium assembly [GO:0044458]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of non-motile cilium assembly [GO:1902857]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000976; GO:0000981; GO:0001228; GO:0005634; GO:0006357; GO:0006974; GO:0010628; GO:0016604; GO:0044458; GO:0045893; GO:0045944; GO:0046872; GO:0070840; GO:1902857 24073 XR_003824984.2 8 14 11 7 22 NA NA NA NA NA NA 24074 XM_029337591.2 395 57 0 0 402 Q7Z2Z2 0 Elongation factor-like GTPase 1 (Elongation factor Tu GTP-binding domain-containing protein 1) (Elongation factor-like 1) (Protein FAM42A) Homo sapiens (Human) cytosolic ribosome assembly [GO:0042256]; GTP metabolic process [GO:0046039] GO:0003746; GO:0003924; GO:0005525; GO:0042256; GO:0043022; GO:0046039; GO:1990904 24075 XM_029346269.2 904 833 437 551 810 P25093 0 Fumarylacetoacetase (FAA) (EC 3.7.1.2) (Beta-diketonase) (Fumarylacetoacetate hydrolase) Rattus norvegicus (Rat) arginine catabolic process [GO:0006527]; homogentisate catabolic process [GO:1902000]; L-phenylalanine catabolic process [GO:0006559]; lipid metabolic process [GO:0006629]; tyrosine catabolic process [GO:0006572] GO:0004334; GO:0006527; GO:0006559; GO:0006572; GO:0006629; GO:0046872; GO:1902000 24076 XM_029325870.2 161 98 80 167 66 NA NA NA NA NA NA 24077 XR_006395276.1 2132 1045 471 2311 1706 NA NA NA NA NA NA 24078 XM_044308477.1 82 45 12 31 28 NA NA NA NA NA NA 24079 XM_044320907.1 101 151 0 49 228 NA NA NA NA NA NA 24080 XM_044316771.1 45 26 18 11 1 NA NA NA NA NA NA 24081 XM_029336757.2 3498 1540 5380 6015 8308 Q9WU63 7.25e-32 Heme-binding protein 2 (Protein SOUL) Mus musculus (Mouse) negative regulation of mitochondrial membrane potential [GO:0010917]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of necrotic cell death [GO:0010940] GO:0005737; GO:0005739; GO:0010917; GO:0010940; GO:0020037; GO:0035794 24082 XM_029336757.2 3498 1540 5380 6015 8308 Q9WU63 1.83e-24 Heme-binding protein 2 (Protein SOUL) Mus musculus (Mouse) negative regulation of mitochondrial membrane potential [GO:0010917]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of necrotic cell death [GO:0010940] GO:0005737; GO:0005739; GO:0010917; GO:0010940; GO:0020037; GO:0035794 24083 XM_044307619.1 66 69 160 384 183 NA NA NA NA NA NA 24084 XM_029346693.2 0 897 0 1526 0 Q6IQX7 5.24e-106 Chondroitin sulfate synthase 2 (EC 2.4.1.175) (EC 2.4.1.226) (Chondroitin glucuronyltransferase 2) (Chondroitin-polymerizing factor) (ChPF) (Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II) (N-acetylgalactosaminyltransferase 2) Mus musculus (Mouse) chondroitin sulfate biosynthetic process [GO:0030206] GO:0005759; GO:0005794; GO:0005829; GO:0008376; GO:0016757; GO:0030206; GO:0032580; GO:0046872; GO:0047238; GO:0050510 24085 XM_029327294.2 366 94 43 556 197 NA NA NA NA NA NA 24086 XM_029356717.2 11 14 24 27 127 Q6DE37 5.71e-95 Glucoside xylosyltransferase 2 (EC 2.4.2.42) (Glycosyltransferase 8 domain-containing protein 4) Xenopus laevis (African clawed frog) O-glycan processing [GO:0016266] GO:0016020; GO:0016266; GO:0035252; GO:0140563 24087 XM_044324388.1 669 305 428 713 314 P35658 1.86e-78 Nuclear pore complex protein Nup214 (214 kDa nucleoporin) (Nucleoporin Nup214) (Protein CAN) Homo sapiens (Human) mitotic cell cycle [GO:0000278]; mRNA export from nucleus [GO:0006406]; nucleocytoplasmic transport [GO:0006913]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; regulation of cell cycle [GO:0051726]; regulation of nucleocytoplasmic transport [GO:0046822]; RNA export from nucleus [GO:0006405] GO:0000278; GO:0005049; GO:0005635; GO:0005643; GO:0005654; GO:0005829; GO:0006405; GO:0006406; GO:0006606; GO:0006611; GO:0006913; GO:0008139; GO:0017056; GO:0046822; GO:0051726; GO:1990876 24088 XM_044324388.1 669 305 428 713 314 P35658 3.27e-33 Nuclear pore complex protein Nup214 (214 kDa nucleoporin) (Nucleoporin Nup214) (Protein CAN) Homo sapiens (Human) mitotic cell cycle [GO:0000278]; mRNA export from nucleus [GO:0006406]; nucleocytoplasmic transport [GO:0006913]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; regulation of cell cycle [GO:0051726]; regulation of nucleocytoplasmic transport [GO:0046822]; RNA export from nucleus [GO:0006405] GO:0000278; GO:0005049; GO:0005635; GO:0005643; GO:0005654; GO:0005829; GO:0006405; GO:0006406; GO:0006606; GO:0006611; GO:0006913; GO:0008139; GO:0017056; GO:0046822; GO:0051726; GO:1990876 24089 XM_044319624.1 96 13 23 34 3 NA NA NA NA NA NA 24090 XM_029337052.2 2533 1802 2511 2177 3161 Q5RCU3 4.53e-118 N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D (N-acyl phosphatidylethanolamine phospholipase D) (NAPE-PLD) (NAPE-hydrolyzing phospholipase D) (EC 3.1.4.54) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) host-mediated regulation of intestinal microbiota composition [GO:0048874]; N-acylphosphatidylethanolamine metabolic process [GO:0070292]; phospholipid catabolic process [GO:0009395]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of inflammatory response [GO:0050729]; temperature homeostasis [GO:0001659] GO:0000139; GO:0001659; GO:0005635; GO:0005654; GO:0005769; GO:0005794; GO:0008270; GO:0009395; GO:0031901; GO:0048874; GO:0050729; GO:0070290; GO:0070292; GO:0090336; GO:0102200 24091 XM_044324337.1 1170 863 582 1034 1074 Q5F415 0 TBC1 domain family member 23 Gallus gallus (Chicken) embryonic brain development [GO:1990403]; retrograde transport, endosome to Golgi [GO:0042147]; vesicle tethering to Golgi [GO:0099041] GO:0005802; GO:0005829; GO:0042147; GO:0099041; GO:1990403 24092 XM_044326809.1 0 2 0 12 11 NA NA NA NA NA NA 24093 XM_044326359.1 660 698 419 613 628 NA NA NA NA NA NA 24094 XM_044326657.1 0 0 3 0 35 Q9VBW3 8.09e-59 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 24095 XM_044328056.1 32 72 128 64 29 NA NA NA NA NA NA 24096 XM_029335654.2 4277 5012 3462 3537 3004 Q9ULC3 9.54e-89 Ras-related protein Rab-23 Homo sapiens (Human) autophagosome assembly [GO:0000045]; cellular defense response [GO:0006968]; cilium assembly [GO:0060271]; craniofacial suture morphogenesis [GO:0097094]; GTP metabolic process [GO:0046039]; intracellular protein transport [GO:0006886]; negative regulation of protein import into nucleus [GO:0042308] GO:0000045; GO:0003924; GO:0005525; GO:0005737; GO:0005776; GO:0005813; GO:0005829; GO:0005886; GO:0006886; GO:0006968; GO:0010008; GO:0012505; GO:0030054; GO:0030670; GO:0042308; GO:0045335; GO:0046039; GO:0060271; GO:0097094 24097 XM_044317544.1 1472 686 540 1286 946 Q92547 0 DNA topoisomerase 2-binding protein 1 (DNA topoisomerase II-beta-binding protein 1) (TopBP1) (DNA topoisomerase II-binding protein 1) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; DNA metabolic process [GO:0006259]; DNA repair [GO:0006281]; DNA replication initiation [GO:0006270]; homologous recombination [GO:0035825]; mitotic DNA replication checkpoint signaling [GO:0033314]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; response to ionizing radiation [GO:0010212] GO:0000794; GO:0000922; GO:0001673; GO:0003677; GO:0005634; GO:0005654; GO:0005694; GO:0005737; GO:0005815; GO:0005886; GO:0006259; GO:0006270; GO:0006281; GO:0006974; GO:0007095; GO:0008022; GO:0010212; GO:0015629; GO:0016604; GO:0016605; GO:0033314; GO:0035825; GO:0042802; GO:0043231; GO:0070532 24098 XM_044316634.1 65 7 21 78 7 NA NA NA NA NA NA 24099 XM_029347881.2 6397 4913 5285 5253 4047 NA NA NA NA NA NA 24100 XM_029355646.2 0 3 19 9 68 P53454 4.85e-27 D(5)-like dopamine receptor Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) regulation of biological quality [GO:0065008] GO:0004930; GO:0005886; GO:0065008 24101 XM_029339681.2 3490 3431 2529 3848 5528 Q9GR88 0 Eukaryotic peptide chain release factor subunit 1 (Eukaryotic release factor 1) (eRF1) Polyandrocarpa misakiensis (Tunicate) NA GO:0003747; GO:0005737 24102 XR_006395928.1 11 19 18 31 28 NA NA NA NA NA NA 24103 XR_006396584.1 0 6 0 0 0 NA NA NA NA NA NA 24104 XM_029338750.2 108 0 0 0 0 Q9BXT4 5.66e-58 Tudor domain-containing protein 1 (Cancer/testis antigen 41.1) (CT41.1) Homo sapiens (Human) DNA methylation involved in gamete generation [GO:0043046]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; P granule organization [GO:0030719]; piRNA processing [GO:0034587]; RNA-mediated gene silencing [GO:0031047]; spermatogenesis [GO:0007283] GO:0005737; GO:0007281; GO:0007283; GO:0030719; GO:0031047; GO:0034587; GO:0043046; GO:0043186; GO:0046872; GO:0051321; GO:0071546 24105 XM_029338750.2 108 0 0 0 0 Q9BXT4 1.95e-53 Tudor domain-containing protein 1 (Cancer/testis antigen 41.1) (CT41.1) Homo sapiens (Human) DNA methylation involved in gamete generation [GO:0043046]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; P granule organization [GO:0030719]; piRNA processing [GO:0034587]; RNA-mediated gene silencing [GO:0031047]; spermatogenesis [GO:0007283] GO:0005737; GO:0007281; GO:0007283; GO:0030719; GO:0031047; GO:0034587; GO:0043046; GO:0043186; GO:0046872; GO:0051321; GO:0071546 24106 XM_029338750.2 108 0 0 0 0 Q9BXT4 3.39e-51 Tudor domain-containing protein 1 (Cancer/testis antigen 41.1) (CT41.1) Homo sapiens (Human) DNA methylation involved in gamete generation [GO:0043046]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; P granule organization [GO:0030719]; piRNA processing [GO:0034587]; RNA-mediated gene silencing [GO:0031047]; spermatogenesis [GO:0007283] GO:0005737; GO:0007281; GO:0007283; GO:0030719; GO:0031047; GO:0034587; GO:0043046; GO:0043186; GO:0046872; GO:0051321; GO:0071546 24107 XM_029338750.2 108 0 0 0 0 Q9BXT4 4.61e-49 Tudor domain-containing protein 1 (Cancer/testis antigen 41.1) (CT41.1) Homo sapiens (Human) DNA methylation involved in gamete generation [GO:0043046]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; P granule organization [GO:0030719]; piRNA processing [GO:0034587]; RNA-mediated gene silencing [GO:0031047]; spermatogenesis [GO:0007283] GO:0005737; GO:0007281; GO:0007283; GO:0030719; GO:0031047; GO:0034587; GO:0043046; GO:0043186; GO:0046872; GO:0051321; GO:0071546 24108 XM_029338750.2 108 0 0 0 0 Q9BXT4 3.06e-43 Tudor domain-containing protein 1 (Cancer/testis antigen 41.1) (CT41.1) Homo sapiens (Human) DNA methylation involved in gamete generation [GO:0043046]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; P granule organization [GO:0030719]; piRNA processing [GO:0034587]; RNA-mediated gene silencing [GO:0031047]; spermatogenesis [GO:0007283] GO:0005737; GO:0007281; GO:0007283; GO:0030719; GO:0031047; GO:0034587; GO:0043046; GO:0043186; GO:0046872; GO:0051321; GO:0071546 24109 XM_029338750.2 108 0 0 0 0 Q9BXT4 1.43e-39 Tudor domain-containing protein 1 (Cancer/testis antigen 41.1) (CT41.1) Homo sapiens (Human) DNA methylation involved in gamete generation [GO:0043046]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; P granule organization [GO:0030719]; piRNA processing [GO:0034587]; RNA-mediated gene silencing [GO:0031047]; spermatogenesis [GO:0007283] GO:0005737; GO:0007281; GO:0007283; GO:0030719; GO:0031047; GO:0034587; GO:0043046; GO:0043186; GO:0046872; GO:0051321; GO:0071546 24110 XM_029338750.2 108 0 0 0 0 Q9BXT4 1.5e-38 Tudor domain-containing protein 1 (Cancer/testis antigen 41.1) (CT41.1) Homo sapiens (Human) DNA methylation involved in gamete generation [GO:0043046]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; P granule organization [GO:0030719]; piRNA processing [GO:0034587]; RNA-mediated gene silencing [GO:0031047]; spermatogenesis [GO:0007283] GO:0005737; GO:0007281; GO:0007283; GO:0030719; GO:0031047; GO:0034587; GO:0043046; GO:0043186; GO:0046872; GO:0051321; GO:0071546 24111 XM_029338750.2 108 0 0 0 0 Q9BXT4 4.58e-33 Tudor domain-containing protein 1 (Cancer/testis antigen 41.1) (CT41.1) Homo sapiens (Human) DNA methylation involved in gamete generation [GO:0043046]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; P granule organization [GO:0030719]; piRNA processing [GO:0034587]; RNA-mediated gene silencing [GO:0031047]; spermatogenesis [GO:0007283] GO:0005737; GO:0007281; GO:0007283; GO:0030719; GO:0031047; GO:0034587; GO:0043046; GO:0043186; GO:0046872; GO:0051321; GO:0071546 24112 XM_029338750.2 108 0 0 0 0 Q9BXT4 1.12e-31 Tudor domain-containing protein 1 (Cancer/testis antigen 41.1) (CT41.1) Homo sapiens (Human) DNA methylation involved in gamete generation [GO:0043046]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; P granule organization [GO:0030719]; piRNA processing [GO:0034587]; RNA-mediated gene silencing [GO:0031047]; spermatogenesis [GO:0007283] GO:0005737; GO:0007281; GO:0007283; GO:0030719; GO:0031047; GO:0034587; GO:0043046; GO:0043186; GO:0046872; GO:0051321; GO:0071546 24113 XM_029337286.2 0 330 0 0 0 Q5SSH7 0 Zinc finger ZZ-type and EF-hand domain-containing protein 1 Mus musculus (Mouse) neuroblast proliferation [GO:0007405]; protein ubiquitination [GO:0016567]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]; visual learning [GO:0008542] GO:0005509; GO:0007405; GO:0008270; GO:0008542; GO:0009986; GO:0016567; GO:0035064; GO:0035249; GO:0045202; GO:0048167; GO:0048786; GO:0050730; GO:0061659; GO:0070577; GO:0098794; GO:0140566 24114 XM_029337286.2 0 330 0 0 0 Q5SSH7 3.33e-113 Zinc finger ZZ-type and EF-hand domain-containing protein 1 Mus musculus (Mouse) neuroblast proliferation [GO:0007405]; protein ubiquitination [GO:0016567]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]; visual learning [GO:0008542] GO:0005509; GO:0007405; GO:0008270; GO:0008542; GO:0009986; GO:0016567; GO:0035064; GO:0035249; GO:0045202; GO:0048167; GO:0048786; GO:0050730; GO:0061659; GO:0070577; GO:0098794; GO:0140566 24115 XM_029337286.2 0 330 0 0 0 Q5SSH7 1.67e-71 Zinc finger ZZ-type and EF-hand domain-containing protein 1 Mus musculus (Mouse) neuroblast proliferation [GO:0007405]; protein ubiquitination [GO:0016567]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]; visual learning [GO:0008542] GO:0005509; GO:0007405; GO:0008270; GO:0008542; GO:0009986; GO:0016567; GO:0035064; GO:0035249; GO:0045202; GO:0048167; GO:0048786; GO:0050730; GO:0061659; GO:0070577; GO:0098794; GO:0140566 24116 XM_029333912.2 33 3 36 40 31 NA NA NA NA NA NA 24117 XM_044320815.1 0 0 14 0 0 NA NA NA NA NA NA 24118 XM_044327388.1 14 9 0 9 0 Q9DAJ5 1.88e-27 Dynein light chain roadblock-type 2 (Dynein light chain 2B, cytoplasmic) Mus musculus (Mouse) microtubule-based movement [GO:0007018] GO:0005737; GO:0005813; GO:0005868; GO:0005874; GO:0007018; GO:0045505 24119 XM_029332440.2 1909 1612 1229 1879 2001 NA NA NA NA NA NA 24120 XM_029356232.2 186 141 124 105 153 Q5VTE6 1.44e-54 Protein angel homolog 2 Homo sapiens (Human) 3'-UTR-mediated mRNA stabilization [GO:0070935]; negative regulation of mitotic cell cycle [GO:0045930] GO:0000175; GO:0003730; GO:0005737; GO:0015030; GO:0045930; GO:0070935 24121 XM_029357985.2 50 22 20 37 37 NA NA NA NA NA NA 24122 XM_029326098.2 0 18 0 12 26 NA NA NA NA NA NA 24123 XM_029332265.2 77 69 163 84 63 Q54PH5 7.49e-62 Pre-mRNA-splicing factor cwc2 Dictyostelium discoideum (Social amoeba) mRNA cis splicing, via spliceosome [GO:0045292]; positive regulation of cell cycle [GO:0045787]; positive regulation of RNA splicing [GO:0033120]; spliceosomal snRNP assembly [GO:0000387] GO:0000387; GO:0000974; GO:0005634; GO:0005681; GO:0017070; GO:0033120; GO:0036002; GO:0045292; GO:0045787; GO:0046872; GO:0071006; GO:0071007 24124 XR_006393958.1 18 0 8 4 14 NA NA NA NA NA NA 24125 XR_006395767.1 0 4 0 1 33 NA NA NA NA NA NA 24126 XR_006392334.1 59 0 12 39 52 NA NA NA NA NA NA 24127 XM_029343661.2 57 0 0 0 237 NA NA NA NA NA NA 24128 XM_044310824.1 57 96 122 68 243 Q7RTR2 1.74e-46 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 24129 XM_044310824.1 57 96 122 68 243 Q7RTR2 6.56e-39 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 24130 XM_044310824.1 57 96 122 68 243 Q7RTR2 4.22e-32 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 24131 XM_029345766.2 49 101 0 23 0 Q9UHD2 2.92e-143 Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1) Homo sapiens (Human) activation of innate immune response [GO:0002218]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; dendritic cell proliferation [GO:0044565]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of gene expression [GO:0010629]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of macroautophagy [GO:0016239]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of xenophagy [GO:1904417]; protein phosphorylation [GO:0006468]; regulation of neuron death [GO:1901214]; regulation of type I interferon production [GO:0032479]; response to virus [GO:0009615]; type I interferon-mediated signaling pathway [GO:0060337] GO:0002218; GO:0003676; GO:0004672; GO:0004674; GO:0005524; GO:0005654; GO:0005737; GO:0005829; GO:0006468; GO:0006954; GO:0007249; GO:0009615; GO:0010629; GO:0016239; GO:0018105; GO:0018107; GO:0019903; GO:0032479; GO:0032481; GO:0032727; GO:0032728; GO:0033138; GO:0042802; GO:0043123; GO:0043231; GO:0044565; GO:0045087; GO:0045944; GO:0050830; GO:0051219; GO:0051607; GO:0060337; GO:0060340; GO:0106310; GO:1901214; GO:1902554; GO:1904417 24132 XM_044313370.1 5 25 0 0 50 Q708S4 2.34e-54 Acid-sensing ion channel 4-A (ASIC4-A) (Acid-sensing ion channel 4.1) (Amiloride-sensitive cation channel 4-A) (ZASIC4.1) Danio rerio (Zebrafish) (Brachydanio rerio) sodium ion transmembrane transport [GO:0035725] GO:0005248; GO:0005261; GO:0005886; GO:0015280; GO:0035725; GO:0045177 24133 XM_029325125.2 1032 1171 623 795 661 Q96B26 4.87e-113 Exosome complex component RRP43 (Exosome component 8) (Opa-interacting protein 2) (OIP-2) (Ribosomal RNA-processing protein 43) (p9) Homo sapiens (Human) exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear mRNA surveillance [GO:0071028]; nuclear polyadenylation-dependent mRNA catabolic process [GO:0071042]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]; rRNA catabolic process [GO:0016075]; U1 snRNA 3'-end processing [GO:0034473]; U4 snRNA 3'-end processing [GO:0034475]; U5 snRNA 3'-end processing [GO:0034476] GO:0000176; GO:0000177; GO:0000178; GO:0000467; GO:0001650; GO:0005634; GO:0005654; GO:0005694; GO:0005730; GO:0005737; GO:0005829; GO:0006396; GO:0006401; GO:0016075; GO:0034427; GO:0034473; GO:0034475; GO:0034476; GO:0035925; GO:0042802; GO:0043231; GO:0043928; GO:0071028; GO:0071035; GO:0071038; GO:0071042; GO:0101019 24134 XM_044327530.1 2117 2875 885 1405 954 NA NA NA NA NA NA 24135 XM_044328611.1 0 31 54 0 95 Q8CEE6 8.99e-116 PAS domain-containing serine/threonine-protein kinase (PAS-kinase) (PASKIN) (EC 2.7.11.1) Mus musculus (Mouse) energy homeostasis [GO:0097009]; intracellular signal transduction [GO:0035556]; negative regulation of glycogen biosynthetic process [GO:0045719]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of glucagon secretion [GO:0070092]; regulation of respiratory gaseous exchange [GO:0043576] GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006468; GO:0035091; GO:0035556; GO:0043576; GO:0045719; GO:0046777; GO:0070092; GO:0097009; GO:0106310 24136 XM_044328611.1 0 31 54 0 95 Q8CEE6 2.48e-63 PAS domain-containing serine/threonine-protein kinase (PAS-kinase) (PASKIN) (EC 2.7.11.1) Mus musculus (Mouse) energy homeostasis [GO:0097009]; intracellular signal transduction [GO:0035556]; negative regulation of glycogen biosynthetic process [GO:0045719]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of glucagon secretion [GO:0070092]; regulation of respiratory gaseous exchange [GO:0043576] GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006468; GO:0035091; GO:0035556; GO:0043576; GO:0045719; GO:0046777; GO:0070092; GO:0097009; GO:0106310 24137 XR_006395931.1 313 229 129 211 250 Q8K2J9 1.03e-64 BTB/POZ domain-containing protein 6 Mus musculus (Mouse) neurogenesis [GO:0022008] GO:0005829; GO:0022008 24138 XM_029340791.2 984 1898 1932 2091 1427 NA NA NA NA NA NA 24139 XM_044320943.1 577 317 331 384 453 Q5ZIJ9 0 E3 ubiquitin-protein ligase MIB2 (EC 2.3.2.27) (Mind bomb homolog 2) (RING-type E3 ubiquitin transferase MIB2) Gallus gallus (Chicken) Notch signaling pathway [GO:0007219]; protein ubiquitination [GO:0016567] GO:0004842; GO:0005737; GO:0007219; GO:0008270; GO:0016567 24140 XM_029339107.2 44 21 110 250 159 NA NA NA NA NA NA 24141 XM_044320131.1 5 0 6 0 8 NA NA NA NA NA NA 24142 XM_029343386.2 114 90 13 156 65 NA NA NA NA NA NA 24143 XM_044308151.1 80 114 115 178 185 NA NA NA NA NA NA 24144 XM_044313729.1 0 0 0 14 0 Q9W735 1.3e-86 Prominin-1-A (Prominin-like protein 1) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005783; GO:0005793; GO:0005886; GO:0005902; GO:0005929; GO:0009986; GO:0015485; GO:0016324; GO:0031528; GO:0071914 24145 XM_044314361.1 32 4 2 0 0 NA NA NA NA NA NA 24146 XM_044309675.1 0 0 6 0 0 Q55E58 3.6e-22 Probable serine/threonine-protein kinase pats1 (EC 2.7.11.1) (Protein associated with the transduction of signal 1) Dictyostelium discoideum (Social amoeba) cheating during chimeric sorocarp development [GO:0099139]; mitotic cytokinesis [GO:0000281]; phosphatidylinositol dephosphorylation [GO:0046856]; protein phosphorylation [GO:0006468] GO:0000281; GO:0004438; GO:0004674; GO:0004721; GO:0005524; GO:0005525; GO:0005829; GO:0006468; GO:0042641; GO:0046856; GO:0099139; GO:0106310 24147 XM_044309176.1 173 196 417 30 1047 NA NA NA NA NA NA 24148 XM_044327649.1 0 0 0 0 44 NA NA NA NA NA NA 24149 XM_029351599.2 192 53 37 180 216 P25115 1.04e-22 D(1B) dopamine receptor (D(5) dopamine receptor) (Dopamine D5 receptor) Rattus norvegicus (Rat) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; associative learning [GO:0008306]; cellular response to catecholamine stimulus [GO:0071870]; chemical synaptic transmission, postsynaptic [GO:0099565]; dopamine receptor signaling pathway [GO:0007212]; long-term synaptic depression [GO:0060292]; mating behavior [GO:0007617]; negative regulation of blood pressure [GO:0045776]; negative regulation of cell migration [GO:0030336]; negative regulation of NAD(P)H oxidase activity [GO:0033861]; negative regulation of protein kinase activity [GO:0006469]; norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001994]; reactive oxygen species metabolic process [GO:0072593]; regulation of female receptivity [GO:0045924]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; regulation of systemic arterial blood pressure by vasopressin [GO:0001992]; response to amphetamine [GO:0001975]; response to cocaine [GO:0042220]; sensitization [GO:0046960]; synaptic transmission, dopaminergic [GO:0001963]; transmission of nerve impulse [GO:0019226]; visual learning [GO:0008542]; wound healing [GO:0042060] GO:0001588; GO:0001963; GO:0001965; GO:0001975; GO:0001992; GO:0001994; GO:0004930; GO:0004952; GO:0005886; GO:0005929; GO:0006469; GO:0007189; GO:0007191; GO:0007212; GO:0007617; GO:0008306; GO:0008542; GO:0019226; GO:0030336; GO:0030424; GO:0030425; GO:0031526; GO:0033861; GO:0035240; GO:0042060; GO:0042220; GO:0043025; GO:0043197; GO:0045776; GO:0045924; GO:0046960; GO:0060170; GO:0060292; GO:0071870; GO:0071880; GO:0072593; GO:0097730; GO:0098839; GO:0098978; GO:0099072; GO:0099565 24150 XM_029329880.2 0 0 8 10 11 NA NA NA NA NA NA 24151 XM_029335591.2 157 0 81 0 137 NA NA NA NA NA NA 24152 XM_029333936.2 2641 2134 2154 2230 2565 P81439 2.61e-30 Equistatin (EI) (Cysteine proteinase inhibitor) Actinia equina (Beadlet anemone) negative regulation of peptidase activity [GO:0010466] GO:0004869; GO:0005576; GO:0010466 24153 XM_029333936.2 2641 2134 2154 2230 2565 P81439 1.41e-26 Equistatin (EI) (Cysteine proteinase inhibitor) Actinia equina (Beadlet anemone) negative regulation of peptidase activity [GO:0010466] GO:0004869; GO:0005576; GO:0010466 24154 XM_029333936.2 2641 2134 2154 2230 2565 P81439 3.87e-25 Equistatin (EI) (Cysteine proteinase inhibitor) Actinia equina (Beadlet anemone) negative regulation of peptidase activity [GO:0010466] GO:0004869; GO:0005576; GO:0010466 24155 XM_029333936.2 2641 2134 2154 2230 2565 P81439 3.77e-22 Equistatin (EI) (Cysteine proteinase inhibitor) Actinia equina (Beadlet anemone) negative regulation of peptidase activity [GO:0010466] GO:0004869; GO:0005576; GO:0010466 24156 XM_029343783.2 3573 3334 2377 2178 1332 Q5ZME8 0 WD40 repeat-containing protein SMU1 (Smu-1 suppressor of mec-8 and unc-52 protein homolog) Gallus gallus (Chicken) mRNA splicing, via spliceosome [GO:0000398]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380] GO:0000381; GO:0000398; GO:0005634; GO:0005737; GO:0008380; GO:0016607; GO:0071005; GO:0071011 24157 XM_044315936.1 18 0 27 6 28 NA NA NA NA NA NA 24158 XM_029333757.2 914 1121 697 925 589 P58200 1.17e-51 Vesicle transport through interaction with t-SNAREs homolog 1B (Vesicle transport v-SNARE protein Vti1-like 1) (Vti1-rp1) Rattus norvegicus (Rat) Golgi to vacuole transport [GO:0006896]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; macroautophagy [GO:0016236]; regulation of protein localization to plasma membrane [GO:1903076]; retrograde transport, endosome to Golgi [GO:0042147]; vesicle fusion [GO:0006906]; vesicle fusion with Golgi apparatus [GO:0048280] GO:0000149; GO:0005484; GO:0005765; GO:0005789; GO:0005794; GO:0005829; GO:0006886; GO:0006891; GO:0006896; GO:0006906; GO:0008021; GO:0012507; GO:0016020; GO:0016236; GO:0019869; GO:0031201; GO:0031901; GO:0031902; GO:0031982; GO:0042147; GO:0043025; GO:0048280; GO:0048471; GO:0055037; GO:0055038; GO:1903076 24159 XM_044329116.1 33 16 4 6 29 NA NA NA NA NA NA 24160 XM_044326408.1 89 104 28 76 160 NA NA NA NA NA NA 24161 XM_029339755.2 4005 13256 5928 12448 6598 Q7TSV3 1.26e-72 Zinc finger MYND domain-containing protein 19 (Melanin-concentrating hormone receptor 1-interacting zinc finger protein) (MCH-R1-interacting zinc finger protein) Rattus norvegicus (Rat) NA GO:0005737; GO:0005886; GO:0016020; GO:0045202; GO:0046872 24162 XM_029325513.2 4410 4127 2570 3859 3222 P20171 2.56e-88 GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed] Rattus norvegicus (Rat) adipose tissue development [GO:0060612]; apoptotic process [GO:0006915]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; fibroblast proliferation [GO:0048144]; insulin receptor signaling pathway [GO:0008286]; intrinsic apoptotic signaling pathway [GO:0097193]; liver development [GO:0001889]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; neuron apoptotic process [GO:0051402]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of GTPase activity [GO:0043547]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type II interferon production [GO:0032729]; positive regulation of wound healing [GO:0090303]; Ras protein signal transduction [GO:0007265]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of MAP kinase activity [GO:0043405]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of transcription by RNA polymerase II [GO:0006357]; response to isolation stress [GO:0035900]; small GTPase mediated signal transduction [GO:0007264]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088] GO:0000139; GO:0001889; GO:0001934; GO:0003924; GO:0003925; GO:0005525; GO:0005794; GO:0005886; GO:0006357; GO:0006897; GO:0006915; GO:0007264; GO:0007265; GO:0008022; GO:0008284; GO:0008285; GO:0008286; GO:0010628; GO:0010629; GO:0010863; GO:0019003; GO:0030335; GO:0032729; GO:0034260; GO:0035900; GO:0042088; GO:0042127; GO:0042832; GO:0043231; GO:0043405; GO:0043406; GO:0043410; GO:0043495; GO:0043524; GO:0043539; GO:0043547; GO:0044877; GO:0045740; GO:0045944; GO:0046330; GO:0046579; GO:0048144; GO:0048146; GO:0048169; GO:0050679; GO:0050852; GO:0051402; GO:0051726; GO:0060612; GO:0070374; GO:0071480; GO:0090303; GO:0090314; GO:0090398; GO:0097193; GO:0098696; GO:0098978; GO:1900029; GO:1905360; GO:2000251; GO:2000630 24163 XM_029345619.2 1925 1656 1011 1433 1446 Q174D3 1.12e-22 Mediator of RNA polymerase II transcription subunit 19 (Mediator complex subunit 19) Aedes aegypti (Yellowfever mosquito) (Culex aegypti) regulation of transcription by RNA polymerase II [GO:0006357] GO:0003712; GO:0006357; GO:0016592 24164 XR_006398133.1 0 0 0 4 8 NA NA NA NA NA NA 24165 XM_044328947.1 9 9 3 2 3 NA NA NA NA NA NA 24166 XM_029343766.2 7 307 99 165 98 NA NA NA NA NA NA 24167 XM_029326364.2 2 71 1 1 70 Q8NHH1 1.04e-125 Tubulin polyglutamylase TTLL11 (EC 6.3.2.-) (Tubulin--tyrosine ligase-like protein 11) Homo sapiens (Human) microtubule cytoskeleton organization [GO:0000226]; microtubule severing [GO:0051013]; protein polyglutamylation [GO:0018095] GO:0000226; GO:0005524; GO:0005829; GO:0005874; GO:0005929; GO:0015631; GO:0018095; GO:0036064; GO:0046872; GO:0051013; GO:0070740 24168 XM_044310636.1 82 48 33 120 38 O94887 9.71e-89 FERM, ARHGEF and pleckstrin domain-containing protein 2 (FERM domain-including RhoGEF) (FIR) (FERM, RhoGEF and pleckstrin domain-containing protein 2) (Pleckstrin homology domain-containing family C member 3) (PH domain-containing family C member 3) Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; cell adhesion [GO:0007155]; hair cycle process [GO:0022405]; neuron remodeling [GO:0016322]; osteoclast differentiation [GO:0030316]; podosome assembly [GO:0071800]; Rac protein signal transduction [GO:0016601]; regulation of integrin activation [GO:0033623]; semaphorin-plexin signaling pathway [GO:0071526] GO:0005085; GO:0005737; GO:0005829; GO:0005856; GO:0007155; GO:0008092; GO:0016322; GO:0016601; GO:0022405; GO:0030316; GO:0031532; GO:0033623; GO:0071526; GO:0071800 24169 XM_029338433.2 991 583 417 360 403 Q5R5S1 2.09e-84 F-box only protein 21 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677 24170 XM_044318326.1 0 0 0 10 3 NA NA NA NA NA NA 24171 XM_044326734.1 17 22 1 11 1 NA NA NA NA NA NA 24172 XR_006396210.1 36 23 4 32 29 Q99570 2.1e-25 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 24173 XM_029344174.2 165 94 126 96 415 Q9JJ09 1.26e-153 Sodium-dependent phosphate transport protein 2B (Sodium-phosphate transport protein 2B) (Na(+)-dependent phosphate cotransporter 2B) (Sodium/phosphate cotransporter 2B) (Na(+)/Pi cotransporter 2B) (NaPi-2b) (Solute carrier family 34 member 2) (rNaPi IIb) Rattus norvegicus (Rat) aging [GO:0007568]; cellular phosphate ion homeostasis [GO:0030643]; in utero embryonic development [GO:0001701]; phosphate ion transport [GO:0006817]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to fructose [GO:0009750]; sodium ion transmembrane transport [GO:0035725]; sodium-dependent phosphate transport [GO:0044341] GO:0001701; GO:0005436; GO:0005903; GO:0006817; GO:0007568; GO:0009750; GO:0016020; GO:0016324; GO:0019904; GO:0030643; GO:0031402; GO:0031526; GO:0031528; GO:0031982; GO:0032355; GO:0035725; GO:0042301; GO:0043627; GO:0044341 24174 XM_044320587.1 0 0 0 0 236 NA NA NA NA NA NA 24175 XM_029339095.2 451 41 98 231 156 Q7L2E3 0 ATP-dependent RNA helicase DHX30 (EC 3.6.4.13) (DEAH box protein 30) Homo sapiens (Human) central nervous system development [GO:0007417]; mitochondrial large ribosomal subunit assembly [GO:1902775] GO:0003682; GO:0003723; GO:0003724; GO:0003725; GO:0005524; GO:0005737; GO:0005739; GO:0005829; GO:0007417; GO:0016887; GO:0035770; GO:0042645; GO:1902775 24176 XM_044307421.1 0 43 65 34 94 NA NA NA NA NA NA 24177 XM_029351569.2 457 184 283 354 522 A4IFG2 0 BTB/POZ domain-containing protein 9 Bos taurus (Bovine) adult locomotory behavior [GO:0008344]; circadian behavior [GO:0048512]; modulation of chemical synaptic transmission [GO:0050804] GO:0005737; GO:0008344; GO:0048512; GO:0050804 24178 XM_044312430.1 24 68 19 116 13 NA NA NA NA NA NA 24179 XM_044315109.1 0 0 53 44 28 NA NA NA NA NA NA 24180 XM_029333944.2 42 47 27 49 46 NA NA NA NA NA NA 24181 XM_029350749.2 2147 766 747 1868 1687 Q0PMD2 8.15e-35 Anthrax toxin receptor 1 Rattus norvegicus (Rat) actin cytoskeleton reorganization [GO:0031532]; blood vessel development [GO:0001568]; negative regulation of extracellular matrix assembly [GO:1901202]; positive regulation of metallopeptidase activity [GO:1905050]; reproductive process [GO:0022414]; substrate adhesion-dependent cell spreading [GO:0034446]; toxin transport [GO:1901998] GO:0001568; GO:0004888; GO:0005518; GO:0005886; GO:0009897; GO:0009986; GO:0022414; GO:0031258; GO:0031527; GO:0031532; GO:0034446; GO:0046872; GO:0051015; GO:1901202; GO:1901998; GO:1905050 24182 XM_044315549.1 2 0 7 18 2 NA NA NA NA NA NA 24183 XM_029348028.2 89 20 0 30 27 NA NA NA NA NA NA 24184 XR_006394379.1 6 1 1 0 0 NA NA NA NA NA NA 24185 XM_044313633.1 73 36 35 27 58 Q6DG03 2.55e-45 Cyclin-D-binding Myb-like transcription factor 1 Danio rerio (Zebrafish) (Brachydanio rerio) cell cycle [GO:0007049]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000976; GO:0000978; GO:0000981; GO:0003700; GO:0005634; GO:0006355; GO:0006357; GO:0007049 24186 XM_029341994.2 92 61 31 49 24 C9D7C2 0 Voltage-dependent calcium channel type A subunit alpha-1 (Cacophony protein) Apis mellifera (Honeybee) regulation of ion transmembrane transport [GO:0034765] GO:0005245; GO:0005509; GO:0005891; GO:0034765 24187 XM_029341994.2 92 61 31 49 24 C9D7C2 1.77e-164 Voltage-dependent calcium channel type A subunit alpha-1 (Cacophony protein) Apis mellifera (Honeybee) regulation of ion transmembrane transport [GO:0034765] GO:0005245; GO:0005509; GO:0005891; GO:0034765 24188 XM_029341994.2 92 61 31 49 24 C9D7C2 4.85e-33 Voltage-dependent calcium channel type A subunit alpha-1 (Cacophony protein) Apis mellifera (Honeybee) regulation of ion transmembrane transport [GO:0034765] GO:0005245; GO:0005509; GO:0005891; GO:0034765 24189 XM_029358141.2 5407 4643 3238 3912 3413 Q9D5V6 2.36e-62 Synapse-associated protein 1 (BSD domain-containing signal transducer and Akt interactor protein) (BSTA) Mus musculus (Mouse) cell differentiation [GO:0030154]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to insulin stimulus [GO:0032869]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; TORC2 signaling [GO:0038203] GO:0005634; GO:0005654; GO:0005737; GO:0005794; GO:0005829; GO:0030154; GO:0030424; GO:0030425; GO:0030426; GO:0031234; GO:0032869; GO:0036120; GO:0038203; GO:0042734; GO:0043204; GO:0045202; GO:0045211; GO:0045600; GO:0048172; GO:0048471; GO:0071364; GO:0071902; GO:1990314 24190 XM_029347375.2 406 188 0 120 152 NA NA NA NA NA NA 24191 XM_044324004.1 0 0 0 15 0 NA NA NA NA NA NA 24192 XM_029336192.2 845 570 242 784 407 NA NA NA NA NA NA 24193 XM_044307672.1 0 0 0 0 32 NA NA NA NA NA NA 24194 XR_006395548.1 0 12 0 83 0 A0A1L8FZ98 5.58e-67 Peroxisome biogenesis factor 2 (EC 2.3.2.27) (EC 2.3.2.36) (Peroxin-2) Xenopus laevis (African clawed frog) pexophagy [GO:0000425]; protein import into peroxisome matrix, receptor recycling [GO:0016562]; response to amino acid starvation [GO:1990928] GO:0000425; GO:0005778; GO:0016562; GO:0046872; GO:0061630; GO:1990928 24195 XM_029339880.2 1331 1246 865 999 1005 NA NA NA NA NA NA 24196 XM_044324182.1 715 868 487 1159 860 NA NA NA NA NA NA 24197 XM_029327164.2 3631 3435 2080 3474 2396 Q32P85 2.05e-47 Dynein light chain roadblock-type 2 (Dynein light chain 2B, cytoplasmic) Bos taurus (Bovine) microtubule-based movement [GO:0007018] GO:0005737; GO:0005813; GO:0005868; GO:0005874; GO:0007018; GO:0045505 24198 XM_044322206.1 541 0 0 686 0 Q5F499 0 Dynamin-like 120 kDa protein, mitochondrial (EC 3.6.5.5) (Optic atrophy protein 1 homolog) [Cleaved into: Dynamin-like 120 kDa protein, form S1] Gallus gallus (Chicken) apoptotic process [GO:0006915]; GTP metabolic process [GO:0046039]; membrane tubulation [GO:0097749]; mitochondrial fusion [GO:0008053] GO:0003924; GO:0005525; GO:0005737; GO:0005743; GO:0005758; GO:0005874; GO:0006915; GO:0008017; GO:0008053; GO:0016020; GO:0031966; GO:0046039; GO:0070300; GO:0097749; GO:1901612 24199 XM_044311639.1 204 133 186 128 455 P81274 9.72e-34 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 24200 XM_044311639.1 204 133 186 128 455 P81274 6.6e-30 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 24201 XM_044311639.1 204 133 186 128 455 P81274 3.52e-26 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 24202 XM_029337181.2 355 134 118 127 137 Q5R868 2.66e-32 Post-GPI attachment to proteins factor 4 (Post-GPI attachment to proteins GalNAc transferase 4) (Transmembrane protein 246) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) GPI anchor biosynthetic process [GO:0006506] GO:0000139; GO:0006506; GO:0016757 24203 XM_044312337.1 0 17 11 1 0 NA NA NA NA NA NA 24204 XR_006396948.1 504 189 174 324 369 NA NA NA NA NA NA 24205 XM_029325639.2 37 0 0 0 37 Q6DFR1 9.12e-60 Solute carrier family 22 member 15 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) ion transport [GO:0006811] GO:0006811; GO:0016020; GO:0022857 24206 XM_029350935.2 13892 18720 6646 11714 7368 Q0Z8U2 6.99e-149 40S ribosomal protein S3 (EC 4.2.99.18) Sus scrofa (Pig) apoptotic process [GO:0006915]; cell division [GO:0051301]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to tumor necrosis factor [GO:0071356]; chromosome segregation [GO:0007059]; DNA repair [GO:0006281]; negative regulation of DNA repair [GO:0045738]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of translation [GO:0017148]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of base-excision repair [GO:1905053]; positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis [GO:2001272]; positive regulation of DNA N-glycosylase activity [GO:1902546]; positive regulation of endodeoxyribonuclease activity [GO:0032079]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902231]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell receptor signaling pathway [GO:0050862]; response to TNF agonist [GO:0061481]; spindle assembly [GO:0051225]; translation [GO:0006412] GO:0000977; GO:0003729; GO:0003735; GO:0004520; GO:0005634; GO:0005730; GO:0005743; GO:0005759; GO:0005844; GO:0006281; GO:0006412; GO:0006915; GO:0007059; GO:0008017; GO:0014069; GO:0017148; GO:0019901; GO:0022627; GO:0030544; GO:0031116; GO:0031397; GO:0032079; GO:0032357; GO:0032358; GO:0032587; GO:0032743; GO:0042104; GO:0043507; GO:0044390; GO:0044877; GO:0045738; GO:0050862; GO:0051018; GO:0051092; GO:0051225; GO:0051301; GO:0051879; GO:0061481; GO:0070181; GO:0070301; GO:0071159; GO:0071356; GO:0072686; GO:0097100; GO:0098556; GO:0140078; GO:0140297; GO:1901224; GO:1902231; GO:1902546; GO:1905053; GO:1990904; GO:2001235; GO:2001272 24207 XM_044316804.1 41 0 19 67 4 P05363 3.61e-35 Substance-K receptor (SKR) (NK-2 receptor) (NK-2R) (Neurokinin A receptor) (Tachykinin receptor 2) Bos taurus (Bovine) positive regulation of flagellated sperm motility [GO:1902093]; regulation of uterine smooth muscle contraction [GO:0070472] GO:0004995; GO:0005886; GO:0016497; GO:0061827; GO:0070472; GO:0097225; GO:1902093 24208 XM_044321433.1 249 575 127 283 841 Q91ZI0 3.43e-64 Cadherin EGF LAG seven-pass G-type receptor 3 Mus musculus (Mouse) axonal fasciculation [GO:0007413]; cell-cell adhesion [GO:0098609]; cilium assembly [GO:0060271]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; planar cell polarity pathway involved in axon guidance [GO:1904938]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] GO:0001932; GO:0004930; GO:0005509; GO:0005886; GO:0007156; GO:0007413; GO:0032880; GO:0036514; GO:0036515; GO:0060271; GO:0097475; GO:0098609; GO:1904938 24209 XM_044321433.1 249 575 127 283 841 Q91ZI0 1.85e-44 Cadherin EGF LAG seven-pass G-type receptor 3 Mus musculus (Mouse) axonal fasciculation [GO:0007413]; cell-cell adhesion [GO:0098609]; cilium assembly [GO:0060271]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; planar cell polarity pathway involved in axon guidance [GO:1904938]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] GO:0001932; GO:0004930; GO:0005509; GO:0005886; GO:0007156; GO:0007413; GO:0032880; GO:0036514; GO:0036515; GO:0060271; GO:0097475; GO:0098609; GO:1904938 24210 XM_044321433.1 249 575 127 283 841 Q91ZI0 2.7e-37 Cadherin EGF LAG seven-pass G-type receptor 3 Mus musculus (Mouse) axonal fasciculation [GO:0007413]; cell-cell adhesion [GO:0098609]; cilium assembly [GO:0060271]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; planar cell polarity pathway involved in axon guidance [GO:1904938]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] GO:0001932; GO:0004930; GO:0005509; GO:0005886; GO:0007156; GO:0007413; GO:0032880; GO:0036514; GO:0036515; GO:0060271; GO:0097475; GO:0098609; GO:1904938 24211 XM_044321433.1 249 575 127 283 841 Q91ZI0 2.7e-32 Cadherin EGF LAG seven-pass G-type receptor 3 Mus musculus (Mouse) axonal fasciculation [GO:0007413]; cell-cell adhesion [GO:0098609]; cilium assembly [GO:0060271]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; planar cell polarity pathway involved in axon guidance [GO:1904938]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] GO:0001932; GO:0004930; GO:0005509; GO:0005886; GO:0007156; GO:0007413; GO:0032880; GO:0036514; GO:0036515; GO:0060271; GO:0097475; GO:0098609; GO:1904938 24212 XM_044314147.1 1 11 15 17 8 NA NA NA NA NA NA 24213 XR_006393770.1 52 3 20 0 8 NA NA NA NA NA NA 24214 XM_029332335.2 542 474 221 440 536 E2RYF8 2.08e-62 Targeting protein for Xklp2 homolog (TPX2 homolog) (Microtubule-associated protein TPX2 homolog) Patiria pectinifera (Starfish) (Asterina pectinifera) activation of protein kinase activity [GO:0032147]; regulation of mitotic spindle organization [GO:0060236] GO:0005634; GO:0005737; GO:0005819; GO:0005874; GO:0032147; GO:0060236 24215 XM_029335360.2 237 119 130 148 53 P30884 6.58e-76 Bone morphogenetic protein 2-B (BMP-2-II) Xenopus laevis (African clawed frog) cartilage development [GO:0051216]; cell differentiation [GO:0030154]; ossification [GO:0001503] GO:0001503; GO:0005125; GO:0005615; GO:0008083; GO:0030154; GO:0051216 24216 XM_029327663.2 754 632 380 691 834 Q4R7L3 0 26S proteasome regulatory subunit 6B (26S proteasome AAA-ATPase subunit RPT3) (Proteasome 26S subunit ATPase 4) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) protein catabolic process [GO:0030163] GO:0005524; GO:0005654; GO:0005829; GO:0016887; GO:0022624; GO:0030163; GO:0036402 24217 XM_044307754.1 58 37 13 133 303 NA NA NA NA NA NA 24218 XM_044308156.1 2079 1925 1391 2033 1358 Q502I9 7.1e-81 F-BAR domain only protein 2 Danio rerio (Zebrafish) (Brachydanio rerio) chordate embryonic development [GO:0043009]; clathrin coat assembly [GO:0048268]; clathrin-dependent endocytosis [GO:0072583]; membrane invagination [GO:0010324]; protein localization to plasma membrane [GO:0072659]; synaptic vesicle endocytosis [GO:0048488] GO:0001786; GO:0005546; GO:0005737; GO:0005886; GO:0005905; GO:0010324; GO:0030136; GO:0035091; GO:0043009; GO:0048268; GO:0048488; GO:0072583; GO:0072659; GO:0098793 24219 XM_044308156.1 2079 1925 1391 2033 1358 Q502I9 6.29e-55 F-BAR domain only protein 2 Danio rerio (Zebrafish) (Brachydanio rerio) chordate embryonic development [GO:0043009]; clathrin coat assembly [GO:0048268]; clathrin-dependent endocytosis [GO:0072583]; membrane invagination [GO:0010324]; protein localization to plasma membrane [GO:0072659]; synaptic vesicle endocytosis [GO:0048488] GO:0001786; GO:0005546; GO:0005737; GO:0005886; GO:0005905; GO:0010324; GO:0030136; GO:0035091; GO:0043009; GO:0048268; GO:0048488; GO:0072583; GO:0072659; GO:0098793 24220 XM_029336773.2 125 2 0 7 103 G5EDE1 1.14e-59 Zinc finger protein GFI1 homolog pag-3 (Pattern of reporter gene expression abnormal protein 3) (Transcription factor pag-3) Caenorhabditis elegans negative regulation of apoptotic process [GO:0043066]; negative regulation of insulin secretion [GO:0046676]; negative regulation of neurotransmitter secretion [GO:0046929]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuroblast fate specification [GO:0014018]; regulation of backward locomotion [GO:0043058]; regulation of forward locomotion [GO:0043059]; regulation of neuron differentiation [GO:0045664]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000978; GO:0001222; GO:0001227; GO:0003700; GO:0003714; GO:0005634; GO:0006357; GO:0014018; GO:0030424; GO:0043058; GO:0043059; GO:0043066; GO:0043204; GO:0045664; GO:0046676; GO:0046872; GO:0046929 24221 XM_029332995.2 156 0 0 0 0 NA NA NA NA NA NA 24222 XM_044308664.1 369 5 8 23 5 Q96CG8 5.57e-44 Collagen triple helix repeat-containing protein 1 Homo sapiens (Human) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005576; GO:0005581; GO:0005615; GO:0016477; GO:0016528; GO:0017147; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0062023; GO:0090090; GO:0090103; GO:0090177 24223 XM_029346924.2 15043 9758 7051 5675 4370 Q90YS3 3.01e-151 40S ribosomal protein S2 Ictalurus punctatus (Channel catfish) (Silurus punctatus) translation [GO:0006412] GO:0003723; GO:0003735; GO:0006412; GO:0015935 24224 XM_029337605.2 402 248 254 341 349 NA NA NA NA NA NA 24225 XM_044327144.1 18 0 3 0 1 NA NA NA NA NA NA 24226 XM_044322952.1 239 145 4 186 466 NA NA NA NA NA NA 24227 XM_029345846.2 318 150 161 272 341 Q76FK4 1.54e-46 Nucleolar protein 8 (Nucleolar protein Nop132) Homo sapiens (Human) protein localization to nucleolus [GO:1902570]; rRNA processing [GO:0006364] GO:0003723; GO:0005694; GO:0005730; GO:0006364; GO:1902570 24228 XM_044324251.1 27 0 25 59 107 Q4R6I5 1.96e-27 Clathrin heavy chain linker domain-containing protein 1 Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA NA 24229 XR_006391513.1 0 1 20 27 1 NA NA NA NA NA NA 24230 XM_044320413.1 185 169 33 108 65 NA NA NA NA NA NA 24231 XM_029352495.2 77 28 19 36 66 A7SG73 1.61e-136 Nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19) (Quinolinate phosphoribosyltransferase [decarboxylating]) (QAPRTase) Nematostella vectensis (Starlet sea anemone) NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213] GO:0004514; GO:0005737; GO:0009435; GO:0034213 24232 XR_006392788.1 0 16 0 32 12 NA NA NA NA NA NA 24233 XM_044326581.1 1467 937 728 1118 935 Q9Y4B6 0 DDB1- and CUL4-associated factor 1 (HIV-1 Vpr-binding protein) (VprBP) (Serine/threonine-protein kinase VPRBP) (EC 2.7.11.1) (Vpr-interacting protein) Homo sapiens (Human) B cell differentiation [GO:0030183]; cell competition in a multicellular organism [GO:0035212]; chromatin organization [GO:0006325]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phosphorylation [GO:0016310]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; V(D)J recombination [GO:0033151] GO:0000122; GO:0001650; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0006325; GO:0016310; GO:0016567; GO:0030183; GO:0030331; GO:0033151; GO:0035212; GO:0043687; GO:0080008; GO:0106310; GO:1990244 24234 XR_006393311.1 0 34 0 0 57 NA NA NA NA NA NA 24235 XM_029357037.2 302 217 137 241 299 Q9CZR2 4.2e-160 N-acetylated-alpha-linked acidic dipeptidase 2 (EC 3.4.17.21) (Glutamate carboxypeptidase III) (GCPIII) (N-acetylaspartylglutamate peptidase II) (NAAG-peptidase II) (N-acetylated-alpha-linked acidic dipeptidase II) (NAALADase II) Mus musculus (Mouse) neurotransmitter catabolic process [GO:0042135]; proteolysis [GO:0006508] GO:0004180; GO:0004181; GO:0005886; GO:0006508; GO:0008233; GO:0016020; GO:0016805; GO:0042135; GO:0046872; GO:0050129 24236 XR_006397199.1 7 2 0 2 0 NA NA NA NA NA NA 24237 XM_044315029.1 0 0 0 35 0 NA NA NA NA NA NA 24238 XM_044316010.1 887 579 265 603 1686 Q7ZVF3 0 Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (EC 1.3.5.1) (Flavoprotein subunit of complex II) (Fp) Danio rerio (Zebrafish) (Brachydanio rerio) mitochondrial electron transport, succinate to ubiquinone [GO:0006121]; tricarboxylic acid cycle [GO:0006099] GO:0000104; GO:0005749; GO:0006099; GO:0006121; GO:0008177; GO:0009055; GO:0050660; GO:0102040 24239 XM_044311119.1 63 37 12 45 23 NA NA NA NA NA NA 24240 XR_003826143.2 72 71 79 22 251 NA NA NA NA NA NA 24241 XM_029347946.2 0 0 37 8 0 NA NA NA NA NA NA 24242 XM_044320768.1 3 29 16 6 70 NA NA NA NA NA NA 24243 XR_006392690.1 103 0 22 64 0 NA NA NA NA NA NA 24244 XM_044325936.1 464 36 639 141 2420 Q09575 4.42e-30 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 24245 XM_044316748.1 0 1 19 2 60 P79218 2.92e-42 Substance-K receptor (SKR) (NK-2 receptor) (NK-2R) (Neurokinin A receptor) (Tachykinin receptor 2) Oryctolagus cuniculus (Rabbit) positive regulation of flagellated sperm motility [GO:1902093]; regulation of uterine smooth muscle contraction [GO:0070472] GO:0004995; GO:0005886; GO:0061827; GO:0070472; GO:0097225; GO:1902093 24246 XR_003825895.2 241 207 149 220 163 NA NA NA NA NA NA 24247 XM_029342298.2 43 25 51 74 193 NA NA NA NA NA NA 24248 XM_044325920.1 0 187 44 95 173 A2RUV0 3.89e-143 Neurogenic locus notch homolog protein 1 (Notch 1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; cilium assembly [GO:0060271]; Notch signaling involved in heart development [GO:0061314]; regulation of developmental process [GO:0050793]; regulation of DNA-templated transcription [GO:0006355] GO:0001525; GO:0005509; GO:0005634; GO:0005886; GO:0006355; GO:0030154; GO:0038023; GO:0050793; GO:0060271; GO:0061314 24249 XM_044325920.1 0 187 44 95 173 A2RUV0 3.17e-138 Neurogenic locus notch homolog protein 1 (Notch 1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; cilium assembly [GO:0060271]; Notch signaling involved in heart development [GO:0061314]; regulation of developmental process [GO:0050793]; regulation of DNA-templated transcription [GO:0006355] GO:0001525; GO:0005509; GO:0005634; GO:0005886; GO:0006355; GO:0030154; GO:0038023; GO:0050793; GO:0060271; GO:0061314 24250 XM_044325920.1 0 187 44 95 173 A2RUV0 4.25e-134 Neurogenic locus notch homolog protein 1 (Notch 1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; cilium assembly [GO:0060271]; Notch signaling involved in heart development [GO:0061314]; regulation of developmental process [GO:0050793]; regulation of DNA-templated transcription [GO:0006355] GO:0001525; GO:0005509; GO:0005634; GO:0005886; GO:0006355; GO:0030154; GO:0038023; GO:0050793; GO:0060271; GO:0061314 24251 XM_044325920.1 0 187 44 95 173 A2RUV0 1.56e-115 Neurogenic locus notch homolog protein 1 (Notch 1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; cilium assembly [GO:0060271]; Notch signaling involved in heart development [GO:0061314]; regulation of developmental process [GO:0050793]; regulation of DNA-templated transcription [GO:0006355] GO:0001525; GO:0005509; GO:0005634; GO:0005886; GO:0006355; GO:0030154; GO:0038023; GO:0050793; GO:0060271; GO:0061314 24252 XM_044325920.1 0 187 44 95 173 A2RUV0 4.26e-110 Neurogenic locus notch homolog protein 1 (Notch 1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; cilium assembly [GO:0060271]; Notch signaling involved in heart development [GO:0061314]; regulation of developmental process [GO:0050793]; regulation of DNA-templated transcription [GO:0006355] GO:0001525; GO:0005509; GO:0005634; GO:0005886; GO:0006355; GO:0030154; GO:0038023; GO:0050793; GO:0060271; GO:0061314 24253 XM_044325920.1 0 187 44 95 173 A2RUV0 1.15e-108 Neurogenic locus notch homolog protein 1 (Notch 1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; cilium assembly [GO:0060271]; Notch signaling involved in heart development [GO:0061314]; regulation of developmental process [GO:0050793]; regulation of DNA-templated transcription [GO:0006355] GO:0001525; GO:0005509; GO:0005634; GO:0005886; GO:0006355; GO:0030154; GO:0038023; GO:0050793; GO:0060271; GO:0061314 24254 XM_044325920.1 0 187 44 95 173 A2RUV0 1.27e-85 Neurogenic locus notch homolog protein 1 (Notch 1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; cilium assembly [GO:0060271]; Notch signaling involved in heart development [GO:0061314]; regulation of developmental process [GO:0050793]; regulation of DNA-templated transcription [GO:0006355] GO:0001525; GO:0005509; GO:0005634; GO:0005886; GO:0006355; GO:0030154; GO:0038023; GO:0050793; GO:0060271; GO:0061314 24255 XM_044319109.1 203 28 120 80 79 NA NA NA NA NA NA 24256 XR_006397069.1 9 8 22 14 90 NA NA NA NA NA NA 24257 XR_006394980.1 122 61 52 102 133 NA NA NA NA NA NA 24258 XM_044324257.1 2557 1148 788 1386 1104 A2AJ76 1.12e-52 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 24259 XM_044324257.1 2557 1148 788 1386 1104 A2AJ76 5.39e-50 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 24260 XM_044324257.1 2557 1148 788 1386 1104 A2AJ76 1.79e-48 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 24261 XM_044324257.1 2557 1148 788 1386 1104 A2AJ76 1.4e-46 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 24262 XM_044324257.1 2557 1148 788 1386 1104 A2AJ76 1.53e-43 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 24263 XM_044324257.1 2557 1148 788 1386 1104 A2AJ76 1.79e-40 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 24264 XM_044324257.1 2557 1148 788 1386 1104 A2AJ76 3.23e-38 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 24265 XM_044324257.1 2557 1148 788 1386 1104 A2AJ76 3.34e-38 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 24266 XM_044324257.1 2557 1148 788 1386 1104 A2AJ76 3.76e-38 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 24267 XM_044324257.1 2557 1148 788 1386 1104 A2AJ76 5.58e-38 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 24268 XM_044324257.1 2557 1148 788 1386 1104 A2AJ76 3.55e-37 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 24269 XM_044324257.1 2557 1148 788 1386 1104 A2AJ76 4.57e-37 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 24270 XM_044324257.1 2557 1148 788 1386 1104 A2AJ76 1.11e-35 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 24271 XM_044324257.1 2557 1148 788 1386 1104 A2AJ76 1.45e-35 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 24272 XM_044324257.1 2557 1148 788 1386 1104 A2AJ76 1.8e-35 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 24273 XM_044324257.1 2557 1148 788 1386 1104 A2AJ76 6.3e-35 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 24274 XM_044324257.1 2557 1148 788 1386 1104 A2AJ76 3.97e-34 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 24275 XM_044324257.1 2557 1148 788 1386 1104 A2AJ76 9.6e-32 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 24276 XM_044324257.1 2557 1148 788 1386 1104 A2AJ76 2.23e-30 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 24277 XM_044324257.1 2557 1148 788 1386 1104 A2AJ76 4.28e-28 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 24278 XM_029342759.2 106 71 104 176 320 Q03188 1.22e-29 Centromere protein C (CENP-C) (Centromere autoantigen C) (Centromere protein C 1) (CENP-C 1) (Interphase centromere complex protein 7) Homo sapiens (Human) attachment of mitotic spindle microtubules to kinetochore [GO:0051315]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; kinetochore assembly [GO:0051382]; mitotic cell cycle [GO:0000278]; monopolar spindle attachment to meiosis I kinetochore [GO:0051455] GO:0000278; GO:0000776; GO:0000779; GO:0003677; GO:0005654; GO:0005721; GO:0005829; GO:0007059; GO:0016604; GO:0019237; GO:0030496; GO:0042802; GO:0051301; GO:0051315; GO:0051382; GO:0051455 24279 XR_003823942.2 4 2 8 12 7 NA NA NA NA NA NA 24280 XM_044314618.1 160 3 163 20 580 NA NA NA NA NA NA 24281 XR_006397217.1 198 66 379 199 0 NA NA NA NA NA NA 24282 XM_044315099.1 8 7 11 0 85 Q8BH74 0 Nuclear pore complex protein Nup107 (107 kDa nucleoporin) (Nucleoporin Nup107) Mus musculus (Mouse) female gonad development [GO:0008585]; mRNA export from nucleus [GO:0006406]; nephron development [GO:0072006]; nuclear pore complex assembly [GO:0051292]; nucleocytoplasmic transport [GO:0006913]; post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000973]; protein import into nucleus [GO:0006606] GO:0000776; GO:0000973; GO:0005635; GO:0005643; GO:0006406; GO:0006606; GO:0006913; GO:0008585; GO:0017056; GO:0031080; GO:0031965; GO:0034399; GO:0051292; GO:0072006 24283 XM_044321708.1 3534 3822 2964 3518 3289 P97554 1.42e-26 DnaJ homolog subfamily B member 9 (Endoplasmic reticulum DNA J domain-containing protein 4) (ER-resident protein ERdj4) (ERdj4) (Microvascular endothelial differentiation gene 1 protein) (Mdg-1) Rattus norvegicus (Rat) B cell differentiation [GO:0030183]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; positive regulation of immunoglobulin production [GO:0002639]; response to endoplasmic reticulum stress [GO:0034976]; response to unfolded protein [GO:0006986]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0002639; GO:0005730; GO:0005737; GO:0005783; GO:0005788; GO:0006986; GO:0030183; GO:0030433; GO:0030544; GO:0034976; GO:0051087; GO:0051787; GO:1903895 24284 XM_029343539.2 0 38 0 0 0 NA NA NA NA NA NA 24285 XM_044311016.1 2 120 49 22 27 NA NA NA NA NA NA 24286 XM_044328084.1 165 122 39 19 71 NA NA NA NA NA NA 24287 XM_044313835.1 1 0 77 0 0 NA NA NA NA NA NA 24288 XM_044327974.1 64 1 55 22 62 O88783 5.08e-23 Coagulation factor V (Activated protein C cofactor) [Cleaved into: Coagulation factor V heavy chain; Coagulation factor V light chain] Mus musculus (Mouse) blood circulation [GO:0008015]; blood coagulation [GO:0007596]; proteolysis [GO:0006508]; response to vitamin K [GO:0032571]; zymogen activation [GO:0031638] GO:0005507; GO:0005576; GO:0005615; GO:0005783; GO:0005794; GO:0006508; GO:0007596; GO:0008015; GO:0031091; GO:0031638; GO:0032571 24289 XM_044329264.1 0 0 0 15 0 NA NA NA NA NA NA 24290 XR_006396513.1 22 0 4 0 33 NA NA NA NA NA NA 24291 XM_044321650.1 899 193 199 36 378 NA NA NA NA NA NA 24292 XM_029333376.2 2597 3017 2088 4623 3840 NA NA NA NA NA NA 24293 XM_044328714.1 253 231 91 189 315 P60670 0 Nuclear protein localization protein 4 homolog (Protein NPL4) Mus musculus (Mouse) Golgi organization [GO:0007030]; negative regulation of RIG-I signaling pathway [GO:0039536]; negative regulation of type I interferon production [GO:0032480]; retrograde protein transport, ER to cytosol [GO:0030970]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0005634; GO:0005783; GO:0005829; GO:0006511; GO:0007030; GO:0030433; GO:0030970; GO:0031625; GO:0032480; GO:0034098; GO:0036435; GO:0036501; GO:0039536; GO:0042175; GO:0043130; GO:0044877; GO:0046872; GO:0051117; GO:0070530 24294 XM_044318139.1 1033 164 28 635 196 NA NA NA NA NA NA 24295 XM_044324617.1 0 0 7 9 0 NA NA NA NA NA NA 24296 XR_006396809.1 8 33 49 0 152 Q8CJG0 0 Protein argonaute-2 (Argonaute2) (mAgo2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (Piwi/argonaute family protein meIF2C2) (Protein slicer) Mus musculus (Mouse) cell differentiation [GO:0030154]; miRNA metabolic process [GO:0010586]; miRNA processing [GO:0035196]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; miRNA-mediated gene silencing by mRNA destabilization [GO:0035279]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; negative regulation of translational initiation [GO:0045947]; positive regulation of angiogenesis [GO:0045766]; positive regulation of gene expression [GO:0010628]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of trophoblast cell migration [GO:1901165]; post-embryonic development [GO:0009791]; pre-miRNA processing [GO:0031054]; RISC complex assembly [GO:0070922]; RNA secondary structure unwinding [GO:0010501]; RNA-mediated gene silencing [GO:0031047]; siRNA processing [GO:0030422]; siRNA-mediated gene silencing by mRNA destabilization [GO:0090625] GO:0000340; GO:0000932; GO:0000993; GO:0001046; GO:0003723; GO:0003725; GO:0003727; GO:0003729; GO:0004521; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0005844; GO:0005845; GO:0008022; GO:0009791; GO:0010501; GO:0010586; GO:0010628; GO:0016442; GO:0030154; GO:0030422; GO:0030425; GO:0031047; GO:0031054; GO:0035196; GO:0035197; GO:0035198; GO:0035278; GO:0035279; GO:0036464; GO:0042985; GO:0045766; GO:0045944; GO:0045947; GO:0046872; GO:0060213; GO:0070062; GO:0070551; GO:0070578; GO:0070922; GO:0090624; GO:0090625; GO:0098808; GO:1900153; GO:1901165; GO:1990904 24297 XR_006392097.1 13 11 0 0 5 NA NA NA NA NA NA 24298 XM_029324177.2 1192 862 560 1569 1405 Q5XIG6 0 N-acetylgalactosamine kinase (EC 2.7.1.157) (GalNAc kinase) (Galactokinase 2) Rattus norvegicus (Rat) galactose metabolic process [GO:0006012] GO:0004335; GO:0005524; GO:0005829; GO:0006012; GO:0033858; GO:0043229 24299 XM_044311129.1 0 0 1 0 16 NA NA NA NA NA NA 24300 XM_044325613.1 22 0 7 33 0 NA NA NA NA NA NA 24301 XM_044315247.1 161 19 230 55 463 NA NA NA NA NA NA 24302 XR_006395353.1 0 11 0 7 0 NA NA NA NA NA NA 24303 XM_044317436.1 0 0 457 276 50 P59015 0 Vacuolar protein sorting-associated protein 18 homolog Danio rerio (Zebrafish) (Brachydanio rerio) apical protein localization [GO:0045176]; bile acid and bile salt transport [GO:0015721]; endosome organization [GO:0007032]; endosome to lysosome transport [GO:0008333]; endosome to pigment granule transport [GO:0043485]; eye pigmentation [GO:0048069]; intracellular protein transport [GO:0006886]; lysosome organization [GO:0007040]; notochord cell vacuolation [GO:0060036]; optokinetic behavior [GO:0007634]; organelle fusion [GO:0048284]; pigment granule maturation [GO:0048757]; vacuole organization [GO:0007033]; vesicle docking involved in exocytosis [GO:0006904] GO:0005765; GO:0005768; GO:0006886; GO:0006904; GO:0007032; GO:0007033; GO:0007040; GO:0007634; GO:0008333; GO:0015721; GO:0030674; GO:0030897; GO:0031902; GO:0043485; GO:0045176; GO:0046872; GO:0048069; GO:0048284; GO:0048757; GO:0060036 24304 XM_029342646.2 8520 4100 4938 8485 8173 Q01833 7.14e-135 Complement C3 [Cleaved into: Complement C3 beta chain; Complement C3 alpha chain; C3a anaphylatoxin; Complement C3b alpha' chain; Complement C3f fragment] Naja naja (Indian cobra) complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; inflammatory response [GO:0006954] GO:0004866; GO:0005615; GO:0006954; GO:0006957; GO:0006958 24305 XM_044328728.1 21 32 0 9 39 Q91611 1.78e-27 Desert hedgehog protein B (EC 3.1.-.-) (Desert hedgehog protein 2) (DHH-2) (Hedgehog protein 4) (X-HH4) [Cleaved into: Desert hedgehog protein B N-product] Xenopus laevis (African clawed frog) cell-cell signaling [GO:0007267]; positive regulation of smoothened signaling pathway [GO:0045880]; protein autoprocessing [GO:0016540]; self proteolysis [GO:0097264] GO:0000139; GO:0005113; GO:0005576; GO:0005789; GO:0005886; GO:0007267; GO:0008233; GO:0016540; GO:0045880; GO:0046872; GO:0097264; GO:0140853 24306 XM_029343028.2 0 0 0 11 1 NA NA NA NA NA NA 24307 XM_044325075.1 2 9 1 0 0 NA NA NA NA NA NA 24308 XM_029346553.2 348 436 169 442 220 NA NA NA NA NA NA 24309 XM_044321661.1 3 15 0 0 4 NA NA NA NA NA NA 24310 XM_044322300.1 21 4 3 10 0 NA NA NA NA NA NA 24311 XM_044319797.1 564 201 184 174 195 A2VDS1 1.2e-153 Selenocysteine lyase (EC 4.4.1.16) Bos taurus (Bovine) NA GO:0005794; GO:0005829; GO:0009000; GO:0016740 24312 XR_006394920.1 1 0 2 7 0 NA NA NA NA NA NA 24313 XM_029344206.2 221 206 207 140 364 NA NA NA NA NA NA 24314 XM_044326080.1 18 0 20 39 7 NA NA NA NA NA NA 24315 XM_044322921.1 1221 1734 1235 1850 2379 Q9H0H5 1.22e-141 Rac GTPase-activating protein 1 (Male germ cell RacGap) (MgcRacGAP) (Protein CYK4 homolog) (CYK4) (HsCYK-4) Homo sapiens (Human) actomyosin contractile ring assembly [GO:0000915]; erythrocyte differentiation [GO:0030218]; mitotic cytokinesis [GO:0000281]; mitotic spindle midzone assembly [GO:0051256]; neuroblast proliferation [GO:0007405]; positive regulation of cytokinesis [GO:0032467]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of embryonic development [GO:0045995]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; spermatogenesis [GO:0007283]; sulfate transport [GO:0008272] GO:0000281; GO:0000915; GO:0001669; GO:0005096; GO:0005547; GO:0005634; GO:0005654; GO:0005819; GO:0005829; GO:0005874; GO:0007266; GO:0007283; GO:0007405; GO:0008017; GO:0008272; GO:0019901; GO:0030218; GO:0030496; GO:0031234; GO:0032154; GO:0032467; GO:0043014; GO:0043015; GO:0045995; GO:0046872; GO:0048487; GO:0051056; GO:0051233; GO:0051256; GO:0051988; GO:0070062; GO:0072686; GO:0090543; GO:0097149 24316 XM_029354069.2 456 263 156 276 311 NA NA NA NA NA NA 24317 XM_044308933.1 0 0 0 6 3 NA NA NA NA NA NA 24318 XM_029331493.2 74 146 99 147 102 P97367 4.68e-113 Homeobox protein Meis2 (Meis1-related protein 1) Mus musculus (Mouse) animal organ morphogenesis [GO:0009887]; brain development [GO:0007420]; embryonic pattern specification [GO:0009880]; eye development [GO:0001654]; negative regulation of myeloid cell differentiation [GO:0045638]; pancreas development [GO:0031016]; positive regulation of cardiac muscle myoblast proliferation [GO:0110024]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; response to growth factor [GO:0070848]; response to mechanical stimulus [GO:0009612]; visual learning [GO:0008542] GO:0000978; GO:0000981; GO:0001228; GO:0001654; GO:0003677; GO:0005634; GO:0006357; GO:0007420; GO:0008134; GO:0008284; GO:0008542; GO:0009612; GO:0009880; GO:0009887; GO:0031016; GO:0043565; GO:0045638; GO:0045931; GO:0045944; GO:0048471; GO:0070848; GO:0110024; GO:1990837 24319 XM_029337703.2 14 0 16 4 1 Q9GRC0 3.66e-76 Serine/threonine-protein kinase mos (EC 2.7.11.1) (Oocyte maturation factor mos) Patiria pectinifera (Starfish) (Asterina pectinifera) female gamete generation [GO:0007292]; female meiosis II [GO:0007147]; negative regulation of mitotic cell cycle [GO:0045930]; protein phosphorylation [GO:0006468] GO:0004709; GO:0005524; GO:0006468; GO:0007147; GO:0007292; GO:0045930; GO:0106310 24320 XR_006394821.1 5 0 17 1 66 NA NA NA NA NA NA 24321 XM_044308344.1 235 93 17 88 92 Q5R4N8 4.77e-170 Alpha-2-macroglobulin (Alpha-2-M) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) negative regulation of peptidase activity [GO:0010466] GO:0004867; GO:0005615; GO:0010466 24322 XM_044308344.1 235 93 17 88 92 Q5R4N8 4.77e-170 Alpha-2-macroglobulin (Alpha-2-M) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) negative regulation of peptidase activity [GO:0010466] GO:0004867; GO:0005615; GO:0010466 24323 XM_029334904.2 4733 5566 3638 6063 5730 E2QWQ2 0 Serine/threonine-protein kinase NLK (EC 2.7.11.24) (Nemo-like kinase) Canis lupus familiaris (Dog) (Canis familiaris) intracellular signal transduction [GO:0035556]; negative regulation of Wnt signaling pathway [GO:0030178]; peptidyl-threonine phosphorylation [GO:0018107]; protein autophosphorylation [GO:0046777]; protein stabilization [GO:0050821]; regulation of DNA-templated transcription [GO:0006355]; serine phosphorylation of STAT protein [GO:0042501]; transforming growth factor beta receptor signaling pathway [GO:0007179]; Wnt signaling pathway [GO:0016055] GO:0000287; GO:0004674; GO:0004707; GO:0005524; GO:0005634; GO:0005737; GO:0006355; GO:0007179; GO:0016055; GO:0018107; GO:0030178; GO:0031625; GO:0035556; GO:0042169; GO:0042501; GO:0046777; GO:0050821; GO:0106310; GO:0140297 24324 XM_029349125.2 10783 9331 5258 7850 5756 NA NA NA NA NA NA 24325 XM_044312798.1 1239 683 305 684 388 NA NA NA NA NA NA 24326 XM_029325256.2 0 2 2 0 48 NA NA NA NA NA NA 24327 XM_044322484.1 56 71 0 19 49 NA NA NA NA NA NA 24328 XM_044308500.1 1226 428 473 463 827 E7FAM5 4.47e-58 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 24329 XM_044308500.1 1226 428 473 463 827 E7FAM5 2.01e-51 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 24330 XM_044313415.1 0 0 0 34 117 D9IQ16 8e-29 Galaxin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 24331 XM_044313415.1 0 0 0 34 117 D9IQ16 6.65e-22 Galaxin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 24332 XR_003826106.2 3 3 0 10 15 NA NA NA NA NA NA 24333 XM_029351079.2 120 71 131 109 58 NA NA NA NA NA NA 24334 XR_006397595.1 417 464 426 595 407 NA NA NA NA NA NA 24335 XM_044307917.1 0 0 8 0 6 Q8L840 6.28e-31 ATP-dependent DNA helicase Q-like 4A (EC 3.6.4.12) (RecQ-like protein 4A) (AtRecQ4A) (AtRecQl4A) (SGS1-like protein) (AtSGS1) Arabidopsis thaliana (Mouse-ear cress) cellular response to abscisic acid stimulus [GO:0071215]; cellular response to cold [GO:0070417]; cellular response to DNA damage stimulus [GO:0006974]; chromosome organization [GO:0051276]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724] GO:0000724; GO:0003676; GO:0005524; GO:0005634; GO:0005694; GO:0005737; GO:0006268; GO:0006281; GO:0006310; GO:0006974; GO:0009378; GO:0009506; GO:0016887; GO:0032508; GO:0043138; GO:0046872; GO:0051276; GO:0070417; GO:0071215 24336 XR_006393235.1 202 75 161 167 420 NA NA NA NA NA NA 24337 XM_044327511.1 749 693 422 570 532 NA NA NA NA NA NA 24338 XR_006393058.1 41 2 25 5 151 NA NA NA NA NA NA 24339 XM_044317750.1 44 227 247 191 298 P53667 3.03e-111 LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; axon extension [GO:0048675]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; nervous system development [GO:0007399]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of axon extension [GO:0045773]; positive regulation of stress fiber assembly [GO:0051496]; protein phosphorylation [GO:0006468]; Rho protein signal transduction [GO:0007266]; signal transduction [GO:0007165]; stress fiber assembly [GO:0043149] GO:0001673; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0005856; GO:0005925; GO:0006468; GO:0007165; GO:0007266; GO:0007399; GO:0016020; GO:0016607; GO:0030027; GO:0030036; GO:0031072; GO:0032233; GO:0038096; GO:0043005; GO:0043149; GO:0045773; GO:0046872; GO:0048675; GO:0051444; GO:0051496; GO:0106310 24340 XM_044319309.1 31 0 65 9 0 P18130 1.17e-29 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) Bos taurus (Bovine) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of vasoconstriction [GO:0045907]; regulation of cardiac muscle contraction [GO:0055117] GO:0001996; GO:0004930; GO:0004937; GO:0005634; GO:0005737; GO:0005886; GO:0005901; GO:0007200; GO:0007204; GO:0007267; GO:0031965; GO:0043410; GO:0045907; GO:0046982; GO:0055117; GO:0071880 24341 XR_006395481.1 0 0 12 0 6 NA NA NA NA NA NA 24342 XM_029352266.2 5797 6906 3699 3388 2105 Q2NL13 1.85e-93 Trafficking protein particle complex subunit 5 Bos taurus (Bovine) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888] GO:0005783; GO:0006888; GO:1990070; GO:1990071; GO:1990072 24343 XM_044328256.1 132 121 89 89 115 NA NA NA NA NA NA 24344 XM_044322950.1 503 525 337 446 665 NA NA NA NA NA NA 24345 XM_044323585.1 3 0 0 3 18 Q99315 8.18e-92 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 24346 XM_029335328.2 2966 2754 1149 1777 1207 Q5U593 3.7e-75 Serine/threonine/tyrosine-interacting protein B (Inactive tyrosine-protein phosphatase STYX-B) Xenopus laevis (African clawed frog) protein dephosphorylation [GO:0006470] GO:0006470; GO:0008138 24347 XM_029329786.2 214 239 92 150 98 Q6AYM1 1.57e-29 Uncharacterized protein C5orf34 homolog Rattus norvegicus (Rat) NA NA 24348 XM_029342622.2 592 762 672 977 1272 Q58A42 1.3e-72 Protein DD3-3 Dictyostelium discoideum (Social amoeba) NA GO:0016020 24349 XM_044310705.1 643 237 459 624 107 NA NA NA NA NA NA 24350 XM_044307212.1 97 29 5 32 0 NA NA NA NA NA NA 24351 XM_029329994.2 237 378 103 358 196 NA NA NA NA NA NA 24352 XM_029333021.2 857 941 521 1590 1490 P10894 9.69e-115 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (EC 3.1.4.11) (PLC-154) (Phosphoinositide phospholipase C-beta-1) (Phospholipase C-beta-1) (PLC-beta-1) Bos taurus (Bovine) interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-15-mediated signaling pathway [GO:0035723]; lipid catabolic process [GO:0016042]; memory [GO:0007613]; phosphatidylinositol metabolic process [GO:0046488]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of JNK cascade [GO:0046330] GO:0004435; GO:0005096; GO:0005509; GO:0005516; GO:0005546; GO:0005737; GO:0005829; GO:0007613; GO:0016042; GO:0016607; GO:0019899; GO:0031965; GO:0035722; GO:0035723; GO:0046330; GO:0046488; GO:0048015; GO:0070498 24353 XM_029325272.2 5 0 5 11 4 NA NA NA NA NA NA 24354 XM_044318582.1 51 6 63 260 154 Q68F72 8.94e-83 Solute carrier family 15 member 4 Xenopus laevis (African clawed frog) dipeptide import across plasma membrane [GO:0140206]; innate immune response [GO:0045087]; mast cell homeostasis [GO:0033023]; peptidoglycan transport [GO:0015835]; positive regulation of innate immune response [GO:0045089]; positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [GO:0070430]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of toll-like receptor 7 signaling pathway [GO:0034157]; positive regulation of toll-like receptor 8 signaling pathway [GO:0034161]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; protein transport [GO:0015031]; regulation of isotype switching to IgG isotypes [GO:0048302]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424] GO:0005290; GO:0005765; GO:0015031; GO:0015333; GO:0015647; GO:0015835; GO:0031901; GO:0033023; GO:0034157; GO:0034161; GO:0034165; GO:0036020; GO:0045087; GO:0045089; GO:0048302; GO:0070424; GO:0070430; GO:0070434; GO:0071916; GO:0140206 24355 XM_044317369.1 501 288 165 210 93 Q96AY4 5.82e-49 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24356 XM_044317369.1 501 288 165 210 93 Q96AY4 1.8e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24357 XM_044317369.1 501 288 165 210 93 Q96AY4 1.27e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24358 XM_044317369.1 501 288 165 210 93 Q96AY4 4.15e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24359 XM_044317369.1 501 288 165 210 93 Q96AY4 1.69e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24360 XM_044317369.1 501 288 165 210 93 Q96AY4 3.65e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24361 XM_044317369.1 501 288 165 210 93 Q96AY4 4e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24362 XM_044317369.1 501 288 165 210 93 Q96AY4 4.57e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24363 XM_044317369.1 501 288 165 210 93 Q96AY4 9.01e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24364 XM_029324992.2 84 24 38 50 108 NA NA NA NA NA NA 24365 XR_006398073.1 58 0 3 2 4 NA NA NA NA NA NA 24366 XM_044316268.1 0 4 9 11 7 NA NA NA NA NA NA 24367 XM_044321599.1 985 956 1705 1157 1721 Q80TV8 1.49e-86 CLIP-associating protein 1 (Cytoplasmic linker-associated protein 1) Mus musculus (Mouse) astral microtubule organization [GO:0030953]; cell division [GO:0051301]; cell migration [GO:0016477]; establishment of cell polarity [GO:0030010]; establishment of mitotic spindle localization [GO:0040001]; establishment of spindle orientation [GO:0051294]; exit from mitosis [GO:0010458]; Golgi organization [GO:0007030]; microtubule anchoring [GO:0034453]; microtubule bundle formation [GO:0001578]; microtubule cytoskeleton organization [GO:0000226]; microtubule nucleation [GO:0007020]; microtubule organizing center organization [GO:0031023]; mitotic spindle assembly [GO:0090307]; mitotic spindle organization [GO:0007052]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of microtubule polymerization or depolymerization [GO:0031111]; negative regulation of stress fiber assembly [GO:0051497]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of exocytosis [GO:0045921]; positive regulation of extracellular matrix disassembly [GO:0090091]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of focal adhesion assembly [GO:0051893]; regulation of gastrulation [GO:0010470]; regulation of microtubule cytoskeleton organization [GO:0070507]; vesicle targeting [GO:0006903] GO:0000226; GO:0000776; GO:0001578; GO:0002162; GO:0005737; GO:0005794; GO:0005813; GO:0005815; GO:0005876; GO:0005881; GO:0005925; GO:0005938; GO:0006903; GO:0007020; GO:0007026; GO:0007030; GO:0007052; GO:0008017; GO:0010458; GO:0010470; GO:0010634; GO:0010717; GO:0015630; GO:0016477; GO:0030010; GO:0030953; GO:0030981; GO:0031023; GO:0031111; GO:0031592; GO:0034453; GO:0040001; GO:0043515; GO:0045180; GO:0045921; GO:0051010; GO:0051294; GO:0051301; GO:0051497; GO:0051893; GO:0070507; GO:0072686; GO:0090091; GO:0090307; GO:1903690; GO:1904261 24368 XM_044321599.1 985 956 1705 1157 1721 Q80TV8 5.33e-73 CLIP-associating protein 1 (Cytoplasmic linker-associated protein 1) Mus musculus (Mouse) astral microtubule organization [GO:0030953]; cell division [GO:0051301]; cell migration [GO:0016477]; establishment of cell polarity [GO:0030010]; establishment of mitotic spindle localization [GO:0040001]; establishment of spindle orientation [GO:0051294]; exit from mitosis [GO:0010458]; Golgi organization [GO:0007030]; microtubule anchoring [GO:0034453]; microtubule bundle formation [GO:0001578]; microtubule cytoskeleton organization [GO:0000226]; microtubule nucleation [GO:0007020]; microtubule organizing center organization [GO:0031023]; mitotic spindle assembly [GO:0090307]; mitotic spindle organization [GO:0007052]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of microtubule polymerization or depolymerization [GO:0031111]; negative regulation of stress fiber assembly [GO:0051497]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of exocytosis [GO:0045921]; positive regulation of extracellular matrix disassembly [GO:0090091]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of focal adhesion assembly [GO:0051893]; regulation of gastrulation [GO:0010470]; regulation of microtubule cytoskeleton organization [GO:0070507]; vesicle targeting [GO:0006903] GO:0000226; GO:0000776; GO:0001578; GO:0002162; GO:0005737; GO:0005794; GO:0005813; GO:0005815; GO:0005876; GO:0005881; GO:0005925; GO:0005938; GO:0006903; GO:0007020; GO:0007026; GO:0007030; GO:0007052; GO:0008017; GO:0010458; GO:0010470; GO:0010634; GO:0010717; GO:0015630; GO:0016477; GO:0030010; GO:0030953; GO:0030981; GO:0031023; GO:0031111; GO:0031592; GO:0034453; GO:0040001; GO:0043515; GO:0045180; GO:0045921; GO:0051010; GO:0051294; GO:0051301; GO:0051497; GO:0051893; GO:0070507; GO:0072686; GO:0090091; GO:0090307; GO:1903690; GO:1904261 24369 XM_044321599.1 985 956 1705 1157 1721 Q80TV8 5.61e-49 CLIP-associating protein 1 (Cytoplasmic linker-associated protein 1) Mus musculus (Mouse) astral microtubule organization [GO:0030953]; cell division [GO:0051301]; cell migration [GO:0016477]; establishment of cell polarity [GO:0030010]; establishment of mitotic spindle localization [GO:0040001]; establishment of spindle orientation [GO:0051294]; exit from mitosis [GO:0010458]; Golgi organization [GO:0007030]; microtubule anchoring [GO:0034453]; microtubule bundle formation [GO:0001578]; microtubule cytoskeleton organization [GO:0000226]; microtubule nucleation [GO:0007020]; microtubule organizing center organization [GO:0031023]; mitotic spindle assembly [GO:0090307]; mitotic spindle organization [GO:0007052]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of microtubule polymerization or depolymerization [GO:0031111]; negative regulation of stress fiber assembly [GO:0051497]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of exocytosis [GO:0045921]; positive regulation of extracellular matrix disassembly [GO:0090091]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of focal adhesion assembly [GO:0051893]; regulation of gastrulation [GO:0010470]; regulation of microtubule cytoskeleton organization [GO:0070507]; vesicle targeting [GO:0006903] GO:0000226; GO:0000776; GO:0001578; GO:0002162; GO:0005737; GO:0005794; GO:0005813; GO:0005815; GO:0005876; GO:0005881; GO:0005925; GO:0005938; GO:0006903; GO:0007020; GO:0007026; GO:0007030; GO:0007052; GO:0008017; GO:0010458; GO:0010470; GO:0010634; GO:0010717; GO:0015630; GO:0016477; GO:0030010; GO:0030953; GO:0030981; GO:0031023; GO:0031111; GO:0031592; GO:0034453; GO:0040001; GO:0043515; GO:0045180; GO:0045921; GO:0051010; GO:0051294; GO:0051301; GO:0051497; GO:0051893; GO:0070507; GO:0072686; GO:0090091; GO:0090307; GO:1903690; GO:1904261 24370 XR_006395207.1 0 2 23 3 10 NA NA NA NA NA NA 24371 XR_006394442.1 34 28 31 56 42 NA NA NA NA NA NA 24372 XM_044323854.1 25 61 0 6 3 NA NA NA NA NA NA 24373 XM_029331975.2 8 9 105 0 36 B0G143 1.37e-84 Mitochondrial substrate carrier family protein ucpB (Solute carrier family 25 member 30 homolog) (Uncoupler protein B) Dictyostelium discoideum (Social amoeba) mitochondrial transport [GO:0006839] GO:0005743; GO:0006839; GO:0022857 24374 XM_029347020.2 5 5 0 0 7 NA NA NA NA NA NA 24375 XM_044328014.1 0 4 18 4 0 Q09575 4.81e-21 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 24376 XM_029332949.2 711 483 309 500 472 Q9P0Z9 1.07e-115 Peroxisomal sarcosine oxidase (PSO) (EC 1.5.3.1) (EC 1.5.3.7) (L-pipecolate oxidase) (L-pipecolic acid oxidase) Homo sapiens (Human) L-lysine catabolic process to acetyl-CoA via L-pipecolate [GO:0033514]; lysine catabolic process [GO:0006554] GO:0005777; GO:0005782; GO:0005829; GO:0006554; GO:0008115; GO:0033514; GO:0050031; GO:0050660 24377 XM_029342493.2 3214 1997 1401 1674 1301 NA NA NA NA NA NA 24378 XM_029348412.2 0 19 102 0 0 Q9JLY0 1.54e-24 Suppressor of cytokine signaling 6 (SOCS-6) (Cytokine-inducible SH2 protein 4) (CIS-4) (Suppressor of cytokine signaling 4) (SOCS-4) Mus musculus (Mouse) intracellular signal transduction [GO:0035556]; negative regulation of signal transduction [GO:0009968]; negative regulation of T cell activation [GO:0050868]; phosphatidylinositol phosphate biosynthetic process [GO:0046854]; proteasomal protein catabolic process [GO:0010498]; protein ubiquitination [GO:0016567]; regulation of growth [GO:0040008] GO:0001772; GO:0005829; GO:0005942; GO:0009968; GO:0010498; GO:0016567; GO:0035556; GO:0040008; GO:0046854; GO:0046935; GO:0050868 24379 XM_029347854.2 320 61 225 114 430 Q14457 1.96e-161 Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197) [Cleaved into: Beclin-1-C 35 kDa; Beclin-1-C 37 kDa] Homo sapiens (Human) aging [GO:0007568]; amyloid-beta metabolic process [GO:0050435]; apoptotic process [GO:0006915]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cell division [GO:0051301]; cellular defense response [GO:0006968]; cellular response to aluminum ion [GO:0071275]; cellular response to amino acid starvation [GO:0034198]; cellular response to copper ion [GO:0071280]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucose starvation [GO:0042149]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to nitrogen starvation [GO:0006995]; defense response to virus [GO:0051607]; early endosome to late endosome transport [GO:0045022]; engulfment of apoptotic cell [GO:0043652]; late endosome to vacuole transport [GO:0045324]; lysosome organization [GO:0007040]; macroautophagy [GO:0016236]; mitophagy [GO:0000423]; mitotic metaphase plate congression [GO:0007080]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagosome assembly [GO:1902902]; negative regulation of cell death [GO:0060548]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of lysosome organization [GO:1905672]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; neuron development [GO:0048666]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of attachment of mitotic spindle microtubules to kinetochore [GO:1902425]; positive regulation of autophagosome assembly [GO:2000786]; positive regulation of autophagy [GO:0010508]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of catalytic activity [GO:0050790]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241]; response to hypoxia [GO:0001666]; response to iron(II) ion [GO:0010040]; response to lead ion [GO:0010288]; response to mitochondrial depolarisation [GO:0098780]; response to vitamin E [GO:0033197]; response to xenobiotic stimulus [GO:0009410]; selective autophagy [GO:0061912]; suppression by virus of host autophagy [GO:0039521] GO:0000045; GO:0000407; GO:0000422; GO:0000423; GO:0001666; GO:0005737; GO:0005768; GO:0005776; GO:0005783; GO:0005789; GO:0005802; GO:0005829; GO:0006468; GO:0006622; GO:0006914; GO:0006915; GO:0006968; GO:0006995; GO:0007040; GO:0007080; GO:0007568; GO:0008285; GO:0009410; GO:0010008; GO:0010040; GO:0010288; GO:0010506; GO:0010508; GO:0010613; GO:0014068; GO:0016236; GO:0016241; GO:0016604; GO:0019898; GO:0019901; GO:0030425; GO:0031625; GO:0031966; GO:0032465; GO:0032801; GO:0033197; GO:0034198; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0039521; GO:0042149; GO:0042802; GO:0043066; GO:0043548; GO:0043652; GO:0045022; GO:0045324; GO:0045335; GO:0048666; GO:0050435; GO:0050790; GO:0051020; GO:0051301; GO:0051607; GO:0060548; GO:0061912; GO:0070301; GO:0071275; GO:0071280; GO:0071364; GO:0097352; GO:0098780; GO:1902425; GO:1902902; GO:1905672; GO:2000378; GO:2000786; GO:2001244 24380 XM_029358733.2 14 0 0 694 0 Q80UJ7 0 Rab3 GTPase-activating protein catalytic subunit (RAB3 GTPase-activating protein 130 kDa subunit) (Rab3-GAP p130) (Rab3-GAP) Mus musculus (Mouse) brain development [GO:0007420]; camera-type eye development [GO:0043010]; establishment of protein localization to endoplasmic reticulum membrane [GO:0097051]; excitatory postsynaptic potential [GO:0060079]; face morphogenesis [GO:0060325]; hypothalamus development [GO:0021854]; lipid droplet organization [GO:0034389]; positive regulation of autophagosome assembly [GO:2000786]; positive regulation of endoplasmic reticulum tubular network organization [GO:1903373]; positive regulation of gene expression [GO:0010628]; positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization [GO:0061646]; positive regulation of GTPase activity [GO:0043547]; positive regulation of protein lipidation [GO:1903061]; protein stabilization [GO:0050821]; regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903233]; regulation of GTPase activity [GO:0043087]; regulation of Rab protein signal transduction [GO:0032483]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic vesicle priming [GO:0010807]; synaptic vesicle transport [GO:0048489] GO:0005085; GO:0005096; GO:0005737; GO:0005794; GO:0005811; GO:0007420; GO:0010628; GO:0010807; GO:0021854; GO:0031267; GO:0032483; GO:0032991; GO:0034389; GO:0043010; GO:0043087; GO:0043547; GO:0048172; GO:0048489; GO:0050821; GO:0060076; GO:0060079; GO:0060325; GO:0061646; GO:0071782; GO:0097051; GO:0098794; GO:1903061; GO:1903233; GO:1903373; GO:2000786 24381 XM_029358733.2 14 0 0 694 0 Q80UJ7 2.81e-54 Rab3 GTPase-activating protein catalytic subunit (RAB3 GTPase-activating protein 130 kDa subunit) (Rab3-GAP p130) (Rab3-GAP) Mus musculus (Mouse) brain development [GO:0007420]; camera-type eye development [GO:0043010]; establishment of protein localization to endoplasmic reticulum membrane [GO:0097051]; excitatory postsynaptic potential [GO:0060079]; face morphogenesis [GO:0060325]; hypothalamus development [GO:0021854]; lipid droplet organization [GO:0034389]; positive regulation of autophagosome assembly [GO:2000786]; positive regulation of endoplasmic reticulum tubular network organization [GO:1903373]; positive regulation of gene expression [GO:0010628]; positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization [GO:0061646]; positive regulation of GTPase activity [GO:0043547]; positive regulation of protein lipidation [GO:1903061]; protein stabilization [GO:0050821]; regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903233]; regulation of GTPase activity [GO:0043087]; regulation of Rab protein signal transduction [GO:0032483]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic vesicle priming [GO:0010807]; synaptic vesicle transport [GO:0048489] GO:0005085; GO:0005096; GO:0005737; GO:0005794; GO:0005811; GO:0007420; GO:0010628; GO:0010807; GO:0021854; GO:0031267; GO:0032483; GO:0032991; GO:0034389; GO:0043010; GO:0043087; GO:0043547; GO:0048172; GO:0048489; GO:0050821; GO:0060076; GO:0060079; GO:0060325; GO:0061646; GO:0071782; GO:0097051; GO:0098794; GO:1903061; GO:1903233; GO:1903373; GO:2000786 24382 XM_029331280.2 682 431 355 698 643 Q8R5C8 2.23e-66 Zinc finger MYND domain-containing protein 11 Mus musculus (Mouse) chromatin organization [GO:0006325]; defense response to virus [GO:0051607]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of JNK cascade [GO:0046329]; regulation of signal transduction [GO:0009966]; regulation of transcription elongation by RNA polymerase II [GO:0034243] GO:0003690; GO:0003714; GO:0005634; GO:0005654; GO:0005694; GO:0006325; GO:0008270; GO:0009966; GO:0034243; GO:0035064; GO:0042393; GO:0043124; GO:0046329; GO:0051607; GO:2001237 24383 XM_044322770.1 0 0 0 7 0 NA NA NA NA NA NA 24384 XM_044315261.1 3 11 22 34 25 P35546 4.73e-60 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; anatomical structure morphogenesis [GO:0009653]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006919; GO:0007156; GO:0007158; GO:0007169; GO:0007399; GO:0009410; GO:0009653; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030182; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0098797; GO:2001241 24385 XM_029345372.2 30 53 40 36 59 Q9NVI1 0 Fanconi anemia group I protein (Protein FACI) Homo sapiens (Human) cell cycle [GO:0007049]; interstrand cross-link repair [GO:0036297]; positive regulation of protein ubiquitination [GO:0031398] GO:0000785; GO:0003677; GO:0005654; GO:0005737; GO:0005829; GO:0007049; GO:0016020; GO:0031398; GO:0036297; GO:0070182; GO:1990391 24386 XM_044307486.1 1124 930 245 2015 345 NA NA NA NA NA NA 24387 XM_044312279.1 50 37 26 30 60 NA NA NA NA NA NA 24388 XR_006394044.1 119 0 16 27 88 NA NA NA NA NA NA 24389 XM_029339650.2 49 165 127 90 98 NA NA NA NA NA NA 24390 XM_044320481.1 11 0 100 9 96 NA NA NA NA NA NA 24391 XM_044328453.1 822 422 482 428 339 Q8BH95 9.69e-134 Enoyl-CoA hydratase, mitochondrial (mECH) (mECH1) (EC 4.2.1.17) (EC 5.3.3.8) (Enoyl-CoA hydratase 1) (ECHS1) (Short-chain enoyl-CoA hydratase) (SCEH) Mus musculus (Mouse) fatty acid beta-oxidation [GO:0006635] GO:0004165; GO:0004300; GO:0005739; GO:0005759; GO:0006635; GO:0043956; GO:0120092 24392 XM_029344763.2 53 7 16 16 32 P56718 2.59e-27 Orexin/Hypocretin receptor type 1 (Hypocretin receptor type 1) (Orexin receptor type 1) (Ox-1-R) (Ox1-R) (Ox1R) Rattus norvegicus (Rat) feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0004930; GO:0005886; GO:0007186; GO:0007218; GO:0007631; GO:0016499; GO:0017046; GO:0051480; GO:0070374 24393 XM_044308788.1 10 7 9 4 17 NA NA NA NA NA NA 24394 XM_029339365.2 1240 1272 557 2362 2760 Q9Z206 1.16e-121 Neuroepithelial cell-transforming gene 1 protein (Rho guanine nucleotide exchange factor 8) Mus musculus (Mouse) cellular response to hydrogen peroxide [GO:0070301]; cellular response to ionizing radiation [GO:0071479]; intracellular signal transduction [GO:0035556]; myoblast migration [GO:0051451]; positive regulation of apoptotic process [GO:0043065]; positive regulation of GTPase activity [GO:0043547]; positive regulation of Rho protein signal transduction [GO:0035025] GO:0005085; GO:0005634; GO:0005737; GO:0035025; GO:0035556; GO:0043065; GO:0043547; GO:0051451; GO:0070301; GO:0071479 24395 XM_029355515.2 66 15 27 27 26 B0JZG0 1.01e-179 Solute carrier family 23 member 2 (Na(+)/L-ascorbic acid transporter 2) (Sodium-dependent vitamin C transporter 2) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) sodium ion transport [GO:0006814] GO:0006814; GO:0015229; GO:0015293; GO:0098590 24396 XM_029331911.2 187 284 201 3 225 Q6B858 1.16e-95 Fibronectin type 3 and ankyrin repeat domains protein 1 (GV14) Bos taurus (Bovine) positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of apoptotic process [GO:0042981] GO:0005634; GO:0005829; GO:0005929; GO:0036064; GO:0042981; GO:0045893; GO:0051091 24397 XM_044317980.1 85 38 0 63 0 NA NA NA NA NA NA 24398 XM_044326904.1 0 24 39 39 43 NA NA NA NA NA NA 24399 XM_029329493.2 3005 3241 2574 2367 1935 Q15102 4.77e-79 Platelet-activating factor acetylhydrolase IB subunit alpha1 (EC 3.1.1.47) (PAF acetylhydrolase 29 kDa subunit) (PAF-AH 29 kDa subunit) (PAF-AH subunit gamma) (PAFAH subunit gamma) Homo sapiens (Human) brain development [GO:0007420]; lipid catabolic process [GO:0016042]; lipid metabolic process [GO:0006629]; nervous system development [GO:0007399]; spermatogenesis [GO:0007283] GO:0003847; GO:0005737; GO:0005829; GO:0006629; GO:0007283; GO:0007399; GO:0007420; GO:0008247; GO:0016020; GO:0016042; GO:0042802; GO:0042803; GO:0044877; GO:0046982; GO:0047179 24400 XM_029333064.2 24 10 34 58 0 Q6UXP7 3.14e-60 Protein FAM151B Homo sapiens (Human) NA GO:0005615 24401 XM_029334747.2 574 809 547 563 729 NA NA NA NA NA NA 24402 XM_044310529.1 242 407 210 2 8 NA NA NA NA NA NA 24403 XM_044307423.1 0 8 0 22 0 NA NA NA NA NA NA 24404 XM_029324823.2 216 135 228 191 73 NA NA NA NA NA NA 24405 XM_029334783.2 2159 1694 1131 2317 2111 P50416 3.3e-175 Carnitine O-palmitoyltransferase 1, liver isoform (CPT1-L) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, liver isoform) (CPT I) (CPTI-L) (Carnitine palmitoyltransferase 1A) Homo sapiens (Human) carnitine metabolic process [GO:0009437]; carnitine shuttle [GO:0006853]; cellular response to fatty acid [GO:0071398]; eating behavior [GO:0042755]; epithelial cell differentiation [GO:0030855]; fatty acid beta-oxidation [GO:0006635]; fatty acid metabolic process [GO:0006631]; glucose metabolic process [GO:0006006]; liver regeneration [GO:0097421]; long-chain fatty acid metabolic process [GO:0001676]; positive regulation of fatty acid beta-oxidation [GO:0032000]; regulation of insulin secretion [GO:0050796]; regulation of lipid storage [GO:0010883]; response to alkaloid [GO:0043279]; response to antibiotic [GO:0046677]; response to ethanol [GO:0045471]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]; response to tetrachloromethane [GO:1904772]; response to xenobiotic stimulus [GO:0009410]; triglyceride metabolic process [GO:0006641] GO:0001676; GO:0004095; GO:0005739; GO:0005741; GO:0006006; GO:0006631; GO:0006635; GO:0006641; GO:0006853; GO:0009410; GO:0009437; GO:0010883; GO:0014070; GO:0016020; GO:0030855; GO:0031667; GO:0032000; GO:0042755; GO:0042802; GO:0043279; GO:0045471; GO:0046677; GO:0050796; GO:0071398; GO:0097421; GO:1904772; GO:1990698 24406 XM_044320112.1 11 0 1 7 0 NA NA NA NA NA NA 24407 XM_029339674.2 240 113 94 115 315 A1A4R8 0 Cell division cycle protein 23 homolog (Anaphase-promoting complex subunit 8) (APC8) (Cyclosome subunit 8) Bos taurus (Bovine) anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; metaphase/anaphase transition of mitotic cell cycle [GO:0007091]; mitotic metaphase plate congression [GO:0007080]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; protein K11-linked ubiquitination [GO:0070979]; protein ubiquitination [GO:0016567] GO:0005680; GO:0005737; GO:0007080; GO:0007091; GO:0016567; GO:0031145; GO:0045842; GO:0051301; GO:0070979 24408 XM_044321067.1 14 11 69 15 383 NA NA NA NA NA NA 24409 XR_003827984.2 21334 4219 5638 5223 2021 NA NA NA NA NA NA 24410 XM_029330761.2 120 26 59 68 165 Q3KQF4 1.35e-101 Leucine-rich repeat-containing protein 69 Xenopus laevis (African clawed frog) NA NA 24411 XM_044319697.1 42 5 8 8 0 F6QEU4 5.9e-89 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 24412 XM_044309161.1 48 158 62 35 30 NA NA NA NA NA NA 24413 XM_029350535.2 45 12 17 19 56 NA NA NA NA NA NA 24414 XM_029328358.2 7 13 2 1 14 NA NA NA NA NA NA 24415 XM_044326812.1 545 605 366 865 849 Q9Y2M2 1.42e-59 Protein SSUH2 homolog (Protein ssu-2 homolog) Homo sapiens (Human) odontogenesis [GO:0042476] GO:0005634; GO:0005737; GO:0031072; GO:0042476; GO:0051082 24416 XM_029324872.2 81 81 85 108 212 NA NA NA NA NA NA 24417 XM_044322203.1 1359 933 701 1387 1249 Q62074 0 Protein kinase C iota type (EC 2.7.11.13) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (nPKC-iota) Mus musculus (Mouse) actin filament organization [GO:0007015]; cell migration [GO:0016477]; cell-cell junction organization [GO:0045216]; cellular response to insulin stimulus [GO:0032869]; establishment of apical/basal cell polarity [GO:0035089]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; eye photoreceptor cell development [GO:0042462]; Golgi vesicle budding [GO:0048194]; intracellular signal transduction [GO:0035556]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron apoptotic process [GO:0043524]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of glucose import [GO:0046326]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; response to interleukin-1 [GO:0070555]; response to peptide hormone [GO:0043434] GO:0000139; GO:0004672; GO:0004674; GO:0004697; GO:0004698; GO:0005524; GO:0005543; GO:0005634; GO:0005737; GO:0005768; GO:0005829; GO:0005886; GO:0005903; GO:0005923; GO:0006468; GO:0007015; GO:0008104; GO:0010976; GO:0015630; GO:0016324; GO:0016477; GO:0018105; GO:0031252; GO:0032869; GO:0034351; GO:0035089; GO:0035556; GO:0042462; GO:0043220; GO:0043434; GO:0043524; GO:0045171; GO:0045177; GO:0045197; GO:0045216; GO:0046326; GO:0046872; GO:0048194; GO:0051092; GO:0060252; GO:0070555; GO:0098685; GO:0098978; GO:0099072; GO:0106310; GO:0120157; GO:1903078; GO:2000353 24418 XM_029336102.2 5990 3219 2997 6050 5172 Q63598 0 Plastin-3 (T-plastin) Rattus norvegicus (Rat) actin filament bundle assembly [GO:0051017]; actin filament network formation [GO:0051639]; bone development [GO:0060348]; inner ear auditory receptor cell differentiation [GO:0042491]; regulation of synaptic vesicle cycle [GO:0098693] GO:0005509; GO:0005737; GO:0005884; GO:0031594; GO:0032420; GO:0032432; GO:0042491; GO:0051015; GO:0051017; GO:0051639; GO:0060348; GO:0098693; GO:0098699 24419 XM_044314049.1 3 0 0 0 38 Q8N0W3 0 L-fucose kinase (Fucokinase) (EC 2.7.1.52) Homo sapiens (Human) carbohydrate phosphorylation [GO:0046835]; GDP-L-fucose salvage [GO:0042352]; response to dopamine [GO:1903350] GO:0005524; GO:0005829; GO:0042352; GO:0046835; GO:0050201; GO:1903350 24420 XR_006396859.1 20 0 13 15 10 NA NA NA NA NA NA 24421 XM_029353764.2 850 406 445 680 704 NA NA NA NA NA NA 24422 XM_044322922.1 1496 744 749 1515 1273 O02695 1.28e-151 Receptor-type tyrosine-protein phosphatase N2 (R-PTP-N2) (EC 3.1.3.-) (EC 3.1.3.48) (M1851) [Cleaved into: IA-2beta60] Macaca nemestrina (Pig-tailed macaque) insulin secretion involved in cellular response to glucose stimulus [GO:0035773]; lipid metabolic process [GO:0006629]; neurotransmitter secretion [GO:0007269]; protein dephosphorylation [GO:0006470] GO:0004725; GO:0006470; GO:0006629; GO:0007269; GO:0030667; GO:0030672; GO:0035773 24423 XM_029340474.2 230 124 141 735 193 Q15811 3.21e-23 Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17) Homo sapiens (Human) clathrin-dependent synaptic vesicle endocytosis [GO:0150007]; endocytosis [GO:0006897]; endosomal transport [GO:0016197]; exocytosis [GO:0006887]; intracellular signal transduction [GO:0035556]; protein localization [GO:0008104]; protein transport [GO:0015031]; regulation of small GTPase mediated signal transduction [GO:0051056] GO:0005085; GO:0005509; GO:0005635; GO:0005737; GO:0005829; GO:0005886; GO:0005905; GO:0006887; GO:0006897; GO:0008104; GO:0015031; GO:0016197; GO:0030027; GO:0035556; GO:0043005; GO:0051056; GO:0055037; GO:0060090; GO:0070064; GO:0098793; GO:0150007 24424 XM_044320605.1 248 0 149 0 174 NA NA NA NA NA NA 24425 XM_044311902.1 16 31 20 2 10 NA NA NA NA NA NA 24426 XM_044327107.1 0 14 20 0 26 NA NA NA NA NA NA 24427 XM_044319259.1 167 454 22 53 103 Q86W24 3.86e-43 NACHT, LRR and PYD domains-containing protein 14 (Nucleotide-binding oligomerization domain protein 5) Homo sapiens (Human) cell differentiation [GO:0030154]; regulation of inflammatory response [GO:0050727]; spermatogenesis [GO:0007283] GO:0005524; GO:0005737; GO:0007283; GO:0030154; GO:0050727 24428 XR_006398006.1 178 107 134 118 437 NA NA NA NA NA NA 24429 XM_044319482.1 3034 2150 1668 4183 4086 F1M3L7 3.08e-66 Epidermal growth factor receptor kinase substrate 8 Rattus norvegicus (Rat) actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin polymerization-dependent cell motility [GO:0070358]; adult locomotory behavior [GO:0008344]; barbed-end actin filament capping [GO:0051016]; behavioral response to ethanol [GO:0048149]; cellular response to leukemia inhibitory factor [GO:1990830]; dendritic cell migration [GO:0036336]; exit from mitosis [GO:0010458]; positive regulation of ruffle assembly [GO:1900029]; Rac protein signal transduction [GO:0016601]; regulation of actin filament length [GO:0030832]; regulation of cell shape [GO:0008360]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; regulation of Rho protein signal transduction [GO:0035023]; Rho protein signal transduction [GO:0007266] GO:0003779; GO:0005886; GO:0005903; GO:0005938; GO:0007266; GO:0008344; GO:0008360; GO:0010458; GO:0014069; GO:0016601; GO:0017146; GO:0030426; GO:0030832; GO:0031267; GO:0031532; GO:0032420; GO:0032421; GO:0032426; GO:0032587; GO:0035023; GO:0036336; GO:0045202; GO:0048149; GO:0051016; GO:0051017; GO:0051764; GO:0070358; GO:0098978; GO:0099072; GO:1900029; GO:1990830 24430 XM_044316051.1 22 0 0 0 0 NA NA NA NA NA NA 24431 XM_029325235.2 719 649 443 757 806 Q9JHI5 0 Isovaleryl-CoA dehydrogenase, mitochondrial (IVD) (EC 1.3.8.4) (Butyryl-CoA dehydrogenase) (EC 1.3.8.1) Mus musculus (Mouse) branched-chain amino acid catabolic process [GO:0009083]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; leucine catabolic process [GO:0006552] GO:0003995; GO:0004085; GO:0005654; GO:0005739; GO:0005759; GO:0006552; GO:0008470; GO:0009083; GO:0031966; GO:0033539; GO:0042802; GO:0050660 24432 XM_029332268.2 1838 927 652 1236 702 NA NA NA NA NA NA 24433 XM_029349524.2 321 294 113 243 226 A7SXG9 1.35e-23 Nematocyst expressed protein 8 (NEP-8) (NEP8) Nematostella vectensis (Starlet sea anemone) NA GO:0005576; GO:0042151; GO:0090729 24434 XR_006392996.1 41 2 25 5 151 NA NA NA NA NA NA 24435 XR_003823851.2 0 4 0 0 10 NA NA NA NA NA NA 24436 XM_029335140.2 47 95 79 102 85 O75689 9.47e-81 Arf-GAP with dual PH domain-containing protein 1 (Centaurin-alpha-1) (Cnt-a1) (Putative MAPK-activating protein PM25) Homo sapiens (Human) cell surface receptor signaling pathway [GO:0007166]; positive regulation of GTPase activity [GO:0043547]; regulation of GTPase activity [GO:0043087] GO:0005096; GO:0005547; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0007166; GO:0043087; GO:0043231; GO:0043533; GO:0043547; GO:0046872; GO:1902936 24437 XM_029324639.2 1954 1848 872 1137 1127 Q5SW96 6.22e-32 Low density lipoprotein receptor adapter protein 1 (Autosomal recessive hypercholesterolemia protein) Homo sapiens (Human) amyloid precursor protein metabolic process [GO:0042982]; cellular response to cytokine stimulus [GO:0071345]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; cholesterol transport [GO:0030301]; low-density lipoprotein particle clearance [GO:0034383]; positive regulation of cholesterol metabolic process [GO:0090205]; positive regulation of low-density lipoprotein particle clearance [GO:1905581]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905602]; positive regulation of vascular associated smooth muscle cell proliferation [GO:1904707]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of protein binding [GO:0043393]; regulation of protein localization to plasma membrane [GO:1903076] GO:0001540; GO:0001784; GO:0005546; GO:0005769; GO:0005829; GO:0005883; GO:0005886; GO:0006898; GO:0008203; GO:0009898; GO:0009925; GO:0030159; GO:0030276; GO:0030301; GO:0030424; GO:0030669; GO:0031623; GO:0034383; GO:0035591; GO:0035612; GO:0035615; GO:0035650; GO:0042632; GO:0042982; GO:0043393; GO:0048260; GO:0050750; GO:0055037; GO:0071345; GO:0090118; GO:0090205; GO:1903076; GO:1904707; GO:1905581; GO:1905602 24438 XM_044325370.1 10 0 0 2 0 NA NA NA NA NA NA 24439 XR_006396400.1 18 0 10 0 38 NA NA NA NA NA NA 24440 XM_044308522.1 1 2 23 0 126 NA NA NA NA NA NA 24441 XM_044307339.1 26 23 12 0 3 Q0V8S9 1.07e-25 Contactin-associated protein-like 5 (Cell recognition molecule Caspr5) Gallus gallus (Chicken) cell adhesion [GO:0007155] GO:0007155; GO:0016020 24442 XM_044314693.1 473 327 172 66 76 I6LDA6 0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (iPGM) (EC 5.4.2.12) (Cofactor-independent phosphoglycerate mutase homolog) Onchocerca volvulus glucose catabolic process [GO:0006007]; glycolytic process [GO:0006096] GO:0004619; GO:0005737; GO:0006007; GO:0006096; GO:0030145 24443 XM_029332917.2 13 0 0 0 0 Q9TTM9 5.39e-21 Alpha-1D adrenergic receptor (Alpha-1D adrenoreceptor) (Alpha-1D adrenoceptor) Sus scrofa (Pig) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of vasoconstriction [GO:0045907] GO:0001996; GO:0004930; GO:0004937; GO:0005886; GO:0007200; GO:0007204; GO:0007267; GO:0043410; GO:0045907; GO:0071880 24444 XM_044324406.1 0 0 15 0 0 NA NA NA NA NA NA 24445 XR_006396057.1 9 0 0 4 51 NA NA NA NA NA NA 24446 XM_029333472.2 3 0 0 12 70 NA NA NA NA NA NA 24447 XM_029336848.2 607 290 147 716 582 Q3UQ28 0 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 24448 XM_029335295.2 0 0 0 0 82 NA NA NA NA NA NA 24449 XM_029346060.2 76 21 9 46 89 Q8CFK2 3.48e-115 Transcription factor IIIB 90 kDa subunit (TFIIIB90) (mTFIIIB90) (B-related factor 1) (BRF-1) Mus musculus (Mouse) DNA-templated transcription initiation [GO:0006352]; positive regulation of transcription by RNA polymerase III [GO:0045945]; regulation of mRNA stability [GO:0043488]; transcription by RNA polymerase III [GO:0006383]; transcription preinitiation complex assembly [GO:0070897] GO:0000126; GO:0000995; GO:0001006; GO:0005634; GO:0006352; GO:0006383; GO:0017025; GO:0043488; GO:0045945; GO:0046872; GO:0070897; GO:0097550 24450 XM_044313023.1 53 8 75 48 304 NA NA NA NA NA NA 24451 XM_029350266.2 112 140 28 84 136 Q8IS64 1.19e-150 Endothelin-converting enzyme homolog (ECE) (EC 3.4.24.-) Locusta migratoria (Migratory locust) proteolysis [GO:0006508] GO:0004175; GO:0004222; GO:0005886; GO:0006508; GO:0008270 24452 XM_029329674.2 407 237 150 222 348 O35680 4.73e-28 28S ribosomal protein S12, mitochondrial (MRP-S12) (S12mt) (MT-RPS12) Mus musculus (Mouse) mitochondrial translation [GO:0032543]; translation [GO:0006412] GO:0003735; GO:0005739; GO:0005743; GO:0005763; GO:0005840; GO:0006412; GO:0032543 24453 XM_044314664.1 38 44 19 70 13 Q14202 3.34e-32 Zinc finger MYM-type protein 3 (Zinc finger protein 261) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; regulation of cell morphogenesis [GO:0022604] GO:0003677; GO:0005654; GO:0007010; GO:0008270; GO:0022604 24454 XM_029336889.2 15 1 15 26 360 NA NA NA NA NA NA 24455 XM_044309002.1 63 199 7 252 92 NA NA NA NA NA NA 24456 XM_044317620.1 2160 1699 1243 2077 2118 Q6XYQ8 3.35e-21 Synaptotagmin-10 (Synaptotagmin X) (SytX) Homo sapiens (Human) calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; chemical synaptic transmission [GO:0007268]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; sensory perception of smell [GO:0007608]; vesicle-mediated transport [GO:0016192] GO:0000149; GO:0001786; GO:0005509; GO:0005544; GO:0005546; GO:0005886; GO:0007268; GO:0007608; GO:0014059; GO:0016192; GO:0017156; GO:0017158; GO:0019905; GO:0030276; GO:0030658; GO:0042803; GO:0045956; GO:0046982; GO:0070382; GO:0071277; GO:0098793; GO:0098978 24457 XM_044326029.1 572 318 177 807 671 Q5R539 3.62e-141 Serrate RNA effector molecule homolog (Arsenite-resistance protein 2) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) mRNA processing [GO:0006397]; neuronal stem cell population maintenance [GO:0097150]; primary miRNA processing [GO:0031053]; regulation of DNA-templated transcription [GO:0006355] GO:0003677; GO:0005654; GO:0005737; GO:0006355; GO:0006397; GO:0031053; GO:0097150 24458 XM_044318119.1 14 38 0 48 54 NA NA NA NA NA NA 24459 XM_044318459.1 8 12 0 0 12 NA NA NA NA NA NA 24460 XM_029358165.2 0 64 50 7 100 O00628 9.39e-128 Peroxisomal targeting signal 2 receptor (PTS2 receptor) (Peroxin-7) Homo sapiens (Human) endochondral ossification [GO:0001958]; ether lipid biosynthetic process [GO:0008611]; fatty acid beta-oxidation [GO:0006635]; neuron migration [GO:0001764]; peroxisome organization [GO:0007031]; protein import into peroxisome matrix [GO:0016558] GO:0001764; GO:0001958; GO:0005053; GO:0005777; GO:0005778; GO:0005782; GO:0005829; GO:0006635; GO:0007031; GO:0008611; GO:0016558; GO:0019899; GO:0042803 24461 XR_006393327.1 4 3 0 9 3 NA NA NA NA NA NA 24462 XR_006396691.1 51 9 17 0 13 NA NA NA NA NA NA 24463 XM_044313877.1 24 25 20 43 93 Q96AY4 1.26e-88 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24464 XM_044313877.1 24 25 20 43 93 Q96AY4 1.19e-84 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24465 XM_044313877.1 24 25 20 43 93 Q96AY4 1.22e-83 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24466 XM_044313530.1 45 0 85 30 111 Q5R4R7 2.7e-37 PHD finger protein 24 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0046872 24467 XM_029339483.2 633 243 1059 297 113 Q91827 3.29e-23 Apoptosis regulator R1 (XR1) Xenopus laevis (African clawed frog) apoptotic process [GO:0006915]; regulation of apoptotic process [GO:0042981] GO:0006915; GO:0016020; GO:0042981 24468 XM_044307996.1 0 0 8 0 0 NA NA NA NA NA NA 24469 XM_044326749.1 13 6 6 7 3 NA NA NA NA NA NA 24470 XR_006392065.1 437 132 287 381 560 NA NA NA NA NA NA 24471 XM_029331606.2 1754 1422 1158 1176 977 Q96FW1 9.39e-102 Ubiquitin thioesterase OTUB1 (EC 3.4.19.12) (Deubiquitinating enzyme OTUB1) (OTU domain-containing ubiquitin aldehyde-binding protein 1) (Otubain-1) (hOTU1) (Ubiquitin-specific-processing protease OTUB1) Homo sapiens (Human) adaptive immune response [GO:0002250]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; negative regulation of double-strand break repair [GO:2000780]; negative regulation of histone H2A K63-linked ubiquitination [GO:1901315]; protein K48-linked deubiquitination [GO:0071108] GO:0002250; GO:0004843; GO:0005634; GO:0005654; GO:0005829; GO:0006281; GO:0006974; GO:0019784; GO:0031625; GO:0043130; GO:0070062; GO:0071108; GO:1901315; GO:2000780 24472 XM_044325034.1 0 28 0 20 42 NA NA NA NA NA NA 24473 XM_029355861.2 8 0 8 17 2 NA NA NA NA NA NA 24474 XM_029346552.2 8 2 1 3 7 NA NA NA NA NA NA 24475 XM_044324876.1 0 0 0 14 41 O88813 0 Long-chain-fatty-acid--CoA ligase 5 (EC 6.2.1.3) (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain acyl-CoA synthetase 5) (LACS 5) Rattus norvegicus (Rat) cellular response to insulin stimulus [GO:0032869]; fatty acid metabolic process [GO:0006631]; long-chain fatty acid metabolic process [GO:0001676]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; positive regulation of long-chain fatty acid import across plasma membrane [GO:0010747]; positive regulation of triglyceride biosynthetic process [GO:0010867]; response to cholesterol [GO:0070723]; response to glucose [GO:0009749]; response to nutrient [GO:0007584]; response to sucrose [GO:0009744] GO:0001676; GO:0004467; GO:0005524; GO:0005739; GO:0005741; GO:0005783; GO:0005789; GO:0005886; GO:0006631; GO:0007584; GO:0009744; GO:0009749; GO:0010747; GO:0010867; GO:0016020; GO:0032869; GO:0035338; GO:0047676; GO:0070723 24476 XM_044308939.1 4 3 20 2 12 NA NA NA NA NA NA 24477 XR_006394298.1 7 3 55 3 98 NA NA NA NA NA NA 24478 XM_029327528.2 36 0 155 0 59 Q19269 6.29e-47 Zinc metalloproteinase nas-14 (EC 3.4.24.-) (Nematode astacin 14) Caenorhabditis elegans proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0006508; GO:0008270 24479 XM_044324398.1 59 0 0 0 14 P35546 1.12e-62 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; anatomical structure morphogenesis [GO:0009653]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006919; GO:0007156; GO:0007158; GO:0007169; GO:0007399; GO:0009410; GO:0009653; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030182; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0098797; GO:2001241 24480 XM_044324398.1 59 0 0 0 14 P35546 1.12e-62 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; anatomical structure morphogenesis [GO:0009653]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006919; GO:0007156; GO:0007158; GO:0007169; GO:0007399; GO:0009410; GO:0009653; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030182; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0098797; GO:2001241 24481 XM_044315688.1 7 2 0 0 32 NA NA NA NA NA NA 24482 XM_029340291.2 19 60 0 29 0 P25931 1.83e-24 RYamide receptor (Neuropeptide Y-like receptor) (NPY-R) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218] GO:0001653; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0016020 24483 XM_044320934.1 953 547 525 640 1063 P51957 1.51e-123 Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (Never in mitosis A-related kinase 4) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2) (Serine/threonine-protein kinase NRK2) Homo sapiens (Human) cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; mitotic cell cycle [GO:0000278]; positive regulation of DNA-templated transcription [GO:0045893]; protein phosphorylation [GO:0006468]; regulation of cellular senescence [GO:2000772]; regulation of response to DNA damage stimulus [GO:2001020] GO:0000278; GO:0004674; GO:0005524; GO:0005737; GO:0005829; GO:0005929; GO:0006468; GO:0006974; GO:0030145; GO:0045893; GO:0051301; GO:0106310; GO:2000772; GO:2001020 24484 XM_029336830.2 25 43 19 23 48 NA NA NA NA NA NA 24485 XM_029358062.2 191 262 122 248 352 Q9D994 2.79e-62 WD repeat-containing protein 38 Mus musculus (Mouse) hematopoietic progenitor cell differentiation [GO:0002244] GO:0002244 24486 XM_029343377.2 87 338 33 79 180 NA NA NA NA NA NA 24487 XM_029353760.2 616 868 416 1555 875 NA NA NA NA NA NA 24488 XM_044309581.1 6 1 3 7 8 NA NA NA NA NA NA 24489 XM_044326287.1 334 208 150 395 278 Q5VU97 5.4e-144 VWFA and cache domain-containing protein 1 (Cache domain-containing protein 1) Homo sapiens (Human) NA GO:0005245; GO:0005891 24490 XM_044317475.1 12763 8855 5911 11376 10715 Q5TC82 1.57e-172 Roquin-1 (Roquin) (EC 2.3.2.27) (RING finger and C3H zinc finger protein 1) (RING finger and CCCH-type zinc finger domain-containing protein 1) (RING finger protein 198) Homo sapiens (Human) 3'-UTR-mediated mRNA destabilization [GO:0061158]; B cell homeostasis [GO:0001782]; cellular response to interleukin-1 [GO:0071347]; lymph node development [GO:0048535]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of germinal center formation [GO:0002635]; negative regulation of T-helper 17 cell differentiation [GO:2000320]; negative regulation of T-helper cell differentiation [GO:0045623]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; P-body assembly [GO:0033962]; positive regulation of mRNA catabolic process [GO:0061014]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; post-transcriptional regulation of gene expression [GO:0010608]; protein polyubiquitination [GO:0000209]; regulation of germinal center formation [GO:0002634]; regulation of miRNA metabolic process [GO:2000628]; regulation of mRNA stability [GO:0043488]; regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900151]; regulation of T cell receptor signaling pathway [GO:0050856]; spleen development [GO:0048536]; T cell homeostasis [GO:0043029]; T cell proliferation [GO:0042098]; T cell receptor signaling pathway [GO:0050852]; T follicular helper cell differentiation [GO:0061470]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000209; GO:0000288; GO:0000932; GO:0000956; GO:0001782; GO:0002634; GO:0002635; GO:0003723; GO:0003725; GO:0003729; GO:0003730; GO:0004842; GO:0006511; GO:0008270; GO:0010494; GO:0010608; GO:0030889; GO:0033962; GO:0035198; GO:0035613; GO:0042098; GO:0043029; GO:0043488; GO:0045623; GO:0046007; GO:0048535; GO:0048536; GO:0050852; GO:0050856; GO:0061014; GO:0061158; GO:0061470; GO:0061630; GO:0071347; GO:1900151; GO:1901224; GO:1905762; GO:2000320; GO:2000628 24491 XM_044312564.1 671 334 125 104 344 NA NA NA NA NA NA 24492 XM_044327548.1 0 0 23 0 0 NA NA NA NA NA NA 24493 XM_029337394.2 376 301 159 212 326 Q99M01 5.03e-159 Phenylalanine--tRNA ligase, mitochondrial (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase) (PheRS) Mus musculus (Mouse) phenylalanyl-tRNA aminoacylation [GO:0006432]; tRNA processing [GO:0008033] GO:0000049; GO:0004826; GO:0005524; GO:0005737; GO:0005739; GO:0005759; GO:0006432; GO:0008033 24494 XM_044317780.1 699 470 514 736 575 Q9D2Z8 9.28e-100 Kinesin-like protein KIF12 Mus musculus (Mouse) microtubule-based movement [GO:0007018] GO:0003777; GO:0005524; GO:0005737; GO:0005815; GO:0005871; GO:0005874; GO:0007018; GO:0008017; GO:0016887; GO:0070062 24495 XM_029333991.2 142 72 0 0 0 NA NA NA NA NA NA 24496 XM_029356770.2 0 0 39 454 145 Q96P65 1.8e-25 Pyroglutamylated RF-amide peptide receptor (AQ27) (G-protein coupled receptor 103) (Orexigenic neuropeptide QRFP receptor) (SP9155) Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:0016020 24497 XR_006398005.1 65 48 22 29 49 NA NA NA NA NA NA 24498 XM_029338755.2 168 407 353 154 371 B3EWZ5 3.73e-110 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 24499 XM_029338755.2 168 407 353 154 371 B3EWZ5 1.19e-108 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 24500 XM_029338755.2 168 407 353 154 371 B3EWZ5 2.78e-105 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 24501 XM_029338755.2 168 407 353 154 371 B3EWZ5 1.01e-104 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 24502 XM_029338755.2 168 407 353 154 371 B3EWZ5 2.91e-94 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 24503 XM_029338755.2 168 407 353 154 371 B3EWZ5 8.68e-91 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 24504 XM_029338755.2 168 407 353 154 371 B3EWZ5 1.45e-87 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 24505 XM_029338755.2 168 407 353 154 371 B3EWZ5 3e-79 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 24506 XM_029338755.2 168 407 353 154 371 B3EWZ5 1.3e-76 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 24507 XM_029338755.2 168 407 353 154 371 B3EWZ5 2.15e-67 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 24508 XM_029338755.2 168 407 353 154 371 B3EWZ5 1.1e-62 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 24509 XM_029338755.2 168 407 353 154 371 B3EWZ5 4.01e-50 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 24510 XM_029338755.2 168 407 353 154 371 B3EWZ5 1.08e-49 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 24511 XM_029338755.2 168 407 353 154 371 B3EWZ5 5.89e-46 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 24512 XM_029338755.2 168 407 353 154 371 B3EWZ5 3.91e-40 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 24513 XM_029338755.2 168 407 353 154 371 B3EWZ5 1.2e-36 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 24514 XM_029338755.2 168 407 353 154 371 B3EWZ5 3.03e-35 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 24515 XM_029338755.2 168 407 353 154 371 B3EWZ5 1.06e-31 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 24516 XM_029338755.2 168 407 353 154 371 B3EWZ5 8.66e-29 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 24517 XM_029338755.2 168 407 353 154 371 B3EWZ5 3.05e-26 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 24518 XM_029338755.2 168 407 353 154 371 B3EWZ5 2.71e-25 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 24519 XM_044317273.1 1810 5192 2674 3014 2251 Q9H4G4 2.19e-31 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Homo sapiens (Human) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070062; GO:0070374 24520 XR_006397956.1 24122 20788 11279 30866 31273 NA NA NA NA NA NA 24521 XM_029329694.2 3300 7029 2192 4241 3878 P55145 2.83e-55 Mesencephalic astrocyte-derived neurotrophic factor (Arginine-rich protein) (Protein ARMET) Homo sapiens (Human) dopaminergic neuron differentiation [GO:0071542]; neuron projection development [GO:0031175]; regulation of response to endoplasmic reticulum stress [GO:1905897]; response to unfolded protein [GO:0006986] GO:0003723; GO:0005576; GO:0005615; GO:0005634; GO:0005783; GO:0005788; GO:0005829; GO:0006986; GO:0008083; GO:0031175; GO:0033018; GO:0048471; GO:0071542; GO:0120146; GO:1905897 24522 XM_029347910.2 2 3 0 13 0 NA NA NA NA NA NA 24523 XM_029357295.2 49 28 0 0 104 NA NA NA NA NA NA 24524 XM_029333400.2 69 41 57 76 83 NA NA NA NA NA NA 24525 XM_044310927.1 98 184 117 168 143 NA NA NA NA NA NA 24526 XM_029348340.2 1527 516 534 662 390 P30051 0 Transcriptional enhancer factor TEF-1 (NTEF-1) (Protein GT-IIC) (TEA domain family member 1) (TEAD-1) (Transcription factor 13) (TCF-13) Mus musculus (Mouse) cellular response to retinoic acid [GO:0071300]; embryonic heart tube morphogenesis [GO:0003143]; embryonic organ development [GO:0048568]; heart development [GO:0007507]; hippo signaling [GO:0035329]; lateral mesoderm development [GO:0048368]; notochord development [GO:0030903]; paraxial mesoderm development [GO:0048339]; positive regulation of cell growth [GO:0030307]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein-containing complex assembly [GO:0065003]; regulation of cell population proliferation [GO:0042127]; regulation of DNA-templated transcription [GO:0006355]; regulation of gene expression [GO:0010468]; regulation of transcription by RNA polymerase II [GO:0006357]; transition between fast and slow fiber [GO:0014883] GO:0000978; GO:0000981; GO:0003143; GO:0003700; GO:0005634; GO:0005654; GO:0005667; GO:0006355; GO:0006357; GO:0007507; GO:0010468; GO:0014883; GO:0030307; GO:0030903; GO:0035329; GO:0042127; GO:0045893; GO:0045944; GO:0048339; GO:0048368; GO:0048568; GO:0065003; GO:0071300; GO:0071902; GO:0140552; GO:1902459; GO:1902895; GO:1990837 24527 XM_044317371.1 601 316 299 738 530 Q96AY4 1.13e-50 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24528 XM_044317371.1 601 316 299 738 530 Q96AY4 5.88e-45 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24529 XM_044317371.1 601 316 299 738 530 Q96AY4 6.19e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24530 XM_044317371.1 601 316 299 738 530 Q96AY4 1.79e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24531 XM_044317371.1 601 316 299 738 530 Q96AY4 6.83e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24532 XM_044317371.1 601 316 299 738 530 Q96AY4 1.98e-37 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24533 XM_044317371.1 601 316 299 738 530 Q96AY4 4.24e-37 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24534 XM_044317371.1 601 316 299 738 530 Q96AY4 2.67e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24535 XM_044317371.1 601 316 299 738 530 Q96AY4 3.88e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24536 XM_044317371.1 601 316 299 738 530 Q96AY4 4.33e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24537 XM_044317491.1 1318 1362 1011 201 1036 B6CJY4 2.37e-21 TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6) Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys) activation of NF-kappaB-inducing kinase activity [GO:0007250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; bone resorption [GO:0045453]; cellular response to DNA damage stimulus [GO:0006974]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; in utero embryonic development [GO:0001701]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-17-mediated signaling pathway [GO:0097400]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of immunoglobulin production [GO:0002637]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088] GO:0000122; GO:0001503; GO:0001701; GO:0001843; GO:0002637; GO:0002726; GO:0004842; GO:0005164; GO:0005634; GO:0005811; GO:0005829; GO:0005938; GO:0006974; GO:0007249; GO:0007250; GO:0008270; GO:0009898; GO:0019886; GO:0030316; GO:0031435; GO:0031624; GO:0031625; GO:0031663; GO:0031666; GO:0031996; GO:0032735; GO:0032743; GO:0032755; GO:0035631; GO:0042088; GO:0042102; GO:0042475; GO:0042802; GO:0042826; GO:0042981; GO:0043011; GO:0043123; GO:0043422; GO:0043507; GO:0045453; GO:0045672; GO:0045944; GO:0047485; GO:0048471; GO:0050852; GO:0051092; GO:0051865; GO:0061630; GO:0070498; GO:0070534; GO:0097400; GO:1901224; GO:1904996; GO:2000679 24538 XM_044314143.1 60 25 56 1 35 NA NA NA NA NA NA 24539 XM_044307265.1 7 0 0 0 0 NA NA NA NA NA NA 24540 XR_003822792.2 37 67 60 19 41 NA NA NA NA NA NA 24541 XM_029354373.2 35 0 83 49 57 A0A0C2SRU0 5.4e-78 Decarboxylase iboD (EC 4.1.1.-) (Ibotenic acid biosynthesis cluster protein D) Amanita muscaria (strain Koide BX008) phospholipid biosynthetic process [GO:0008654] GO:0004609; GO:0008654 24542 XM_029323888.2 198 204 82 438 454 Q6AXC6 0 ATP-dependent DNA helicase DDX11 (EC 3.6.4.12) (DEAD/H-box protein 11) Mus musculus (Mouse) cellular response to bleomycin [GO:1904976]; cellular response to cisplatin [GO:0072719]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hydroxyurea [GO:0072711]; DNA duplex unwinding [GO:0032508]; DNA repair [GO:0006281]; establishment of sister chromatid cohesion [GO:0034085]; G-quadruplex DNA unwinding [GO:0044806]; negative regulation of protein binding [GO:0032091]; nucleolar chromatin organization [GO:1990700]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of endodeoxyribonuclease activity [GO:0032079]; positive regulation of sister chromatid cohesion [GO:0045876]; positive regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901838]; replication fork processing [GO:0031297]; sister chromatid cohesion [GO:0007062] GO:0000785; GO:0000922; GO:0003677; GO:0003678; GO:0003682; GO:0003688; GO:0003690; GO:0003697; GO:0003727; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005813; GO:0006281; GO:0006974; GO:0007062; GO:0008094; GO:0008186; GO:0016887; GO:0030496; GO:0031297; GO:0031390; GO:0032079; GO:0032091; GO:0032508; GO:0034085; GO:0035563; GO:0043139; GO:0044806; GO:0045142; GO:0045876; GO:0046872; GO:0051539; GO:0051880; GO:0070062; GO:0072711; GO:0072719; GO:1901838; GO:1904976; GO:1990700; GO:2000781 24543 XM_044308836.1 125 60 51 216 28 Q4R5Y0 1.22e-34 Uncharacterized protein CFAP68 (cilia and flagella associated protein 68) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0005634 24544 XM_029330626.2 723 813 1354 2027 1335 P22105 1.61e-48 Tenascin-X (TN-X) (Hexabrachion-like protein) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; elastic fiber assembly [GO:0048251]; extracellular matrix organization [GO:0030198]; fatty acid metabolic process [GO:0006631]; positive regulation of cell fate determination [GO:1905935]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen fibril organization [GO:1904028]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of transforming growth factor beta activation [GO:1901390]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of cell migration [GO:0030334]; regulation of JUN kinase activity [GO:0043506]; triglyceride metabolic process [GO:0006641] GO:0005178; GO:0005201; GO:0005518; GO:0005576; GO:0005615; GO:0006631; GO:0006641; GO:0007155; GO:0007160; GO:0008201; GO:0008284; GO:0010718; GO:0010862; GO:0030036; GO:0030155; GO:0030198; GO:0030199; GO:0030334; GO:0030511; GO:0031012; GO:0032963; GO:0043506; GO:0045595; GO:0048251; GO:0062023; GO:0070062; GO:0090733; GO:0098609; GO:0098633; GO:1900748; GO:1901390; GO:1904028; GO:1905935 24545 XM_029330626.2 723 813 1354 2027 1335 P22105 2.43e-48 Tenascin-X (TN-X) (Hexabrachion-like protein) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; elastic fiber assembly [GO:0048251]; extracellular matrix organization [GO:0030198]; fatty acid metabolic process [GO:0006631]; positive regulation of cell fate determination [GO:1905935]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen fibril organization [GO:1904028]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of transforming growth factor beta activation [GO:1901390]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of cell migration [GO:0030334]; regulation of JUN kinase activity [GO:0043506]; triglyceride metabolic process [GO:0006641] GO:0005178; GO:0005201; GO:0005518; GO:0005576; GO:0005615; GO:0006631; GO:0006641; GO:0007155; GO:0007160; GO:0008201; GO:0008284; GO:0010718; GO:0010862; GO:0030036; GO:0030155; GO:0030198; GO:0030199; GO:0030334; GO:0030511; GO:0031012; GO:0032963; GO:0043506; GO:0045595; GO:0048251; GO:0062023; GO:0070062; GO:0090733; GO:0098609; GO:0098633; GO:1900748; GO:1901390; GO:1904028; GO:1905935 24546 XM_029330626.2 723 813 1354 2027 1335 P22105 5.92e-46 Tenascin-X (TN-X) (Hexabrachion-like protein) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; elastic fiber assembly [GO:0048251]; extracellular matrix organization [GO:0030198]; fatty acid metabolic process [GO:0006631]; positive regulation of cell fate determination [GO:1905935]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen fibril organization [GO:1904028]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of transforming growth factor beta activation [GO:1901390]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of cell migration [GO:0030334]; regulation of JUN kinase activity [GO:0043506]; triglyceride metabolic process [GO:0006641] GO:0005178; GO:0005201; GO:0005518; GO:0005576; GO:0005615; GO:0006631; GO:0006641; GO:0007155; GO:0007160; GO:0008201; GO:0008284; GO:0010718; GO:0010862; GO:0030036; GO:0030155; GO:0030198; GO:0030199; GO:0030334; GO:0030511; GO:0031012; GO:0032963; GO:0043506; GO:0045595; GO:0048251; GO:0062023; GO:0070062; GO:0090733; GO:0098609; GO:0098633; GO:1900748; GO:1901390; GO:1904028; GO:1905935 24547 XM_029330626.2 723 813 1354 2027 1335 P22105 7.24e-46 Tenascin-X (TN-X) (Hexabrachion-like protein) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; elastic fiber assembly [GO:0048251]; extracellular matrix organization [GO:0030198]; fatty acid metabolic process [GO:0006631]; positive regulation of cell fate determination [GO:1905935]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen fibril organization [GO:1904028]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of transforming growth factor beta activation [GO:1901390]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of cell migration [GO:0030334]; regulation of JUN kinase activity [GO:0043506]; triglyceride metabolic process [GO:0006641] GO:0005178; GO:0005201; GO:0005518; GO:0005576; GO:0005615; GO:0006631; GO:0006641; GO:0007155; GO:0007160; GO:0008201; GO:0008284; GO:0010718; GO:0010862; GO:0030036; GO:0030155; GO:0030198; GO:0030199; GO:0030334; GO:0030511; GO:0031012; GO:0032963; GO:0043506; GO:0045595; GO:0048251; GO:0062023; GO:0070062; GO:0090733; GO:0098609; GO:0098633; GO:1900748; GO:1901390; GO:1904028; GO:1905935 24548 XM_029330626.2 723 813 1354 2027 1335 P22105 1.51e-45 Tenascin-X (TN-X) (Hexabrachion-like protein) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; elastic fiber assembly [GO:0048251]; extracellular matrix organization [GO:0030198]; fatty acid metabolic process [GO:0006631]; positive regulation of cell fate determination [GO:1905935]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen fibril organization [GO:1904028]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of transforming growth factor beta activation [GO:1901390]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of cell migration [GO:0030334]; regulation of JUN kinase activity [GO:0043506]; triglyceride metabolic process [GO:0006641] GO:0005178; GO:0005201; GO:0005518; GO:0005576; GO:0005615; GO:0006631; GO:0006641; GO:0007155; GO:0007160; GO:0008201; GO:0008284; GO:0010718; GO:0010862; GO:0030036; GO:0030155; GO:0030198; GO:0030199; GO:0030334; GO:0030511; GO:0031012; GO:0032963; GO:0043506; GO:0045595; GO:0048251; GO:0062023; GO:0070062; GO:0090733; GO:0098609; GO:0098633; GO:1900748; GO:1901390; GO:1904028; GO:1905935 24549 XM_029330626.2 723 813 1354 2027 1335 P22105 3.12e-36 Tenascin-X (TN-X) (Hexabrachion-like protein) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; elastic fiber assembly [GO:0048251]; extracellular matrix organization [GO:0030198]; fatty acid metabolic process [GO:0006631]; positive regulation of cell fate determination [GO:1905935]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen fibril organization [GO:1904028]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of transforming growth factor beta activation [GO:1901390]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of cell migration [GO:0030334]; regulation of JUN kinase activity [GO:0043506]; triglyceride metabolic process [GO:0006641] GO:0005178; GO:0005201; GO:0005518; GO:0005576; GO:0005615; GO:0006631; GO:0006641; GO:0007155; GO:0007160; GO:0008201; GO:0008284; GO:0010718; GO:0010862; GO:0030036; GO:0030155; GO:0030198; GO:0030199; GO:0030334; GO:0030511; GO:0031012; GO:0032963; GO:0043506; GO:0045595; GO:0048251; GO:0062023; GO:0070062; GO:0090733; GO:0098609; GO:0098633; GO:1900748; GO:1901390; GO:1904028; GO:1905935 24550 XM_029324977.2 7 11 0 13 0 NA NA NA NA NA NA 24551 XM_029323920.2 51 19 48 34 58 NA NA NA NA NA NA 24552 XR_003827136.2 3 3 20 1 48 NA NA NA NA NA NA 24553 XM_044325694.1 7 33 83 37 111 NA NA NA NA NA NA 24554 XM_044325557.1 81 0 77 0 0 NA NA NA NA NA NA 24555 XM_044320648.1 201 372 468 367 199 NA NA NA NA NA NA 24556 XM_044318160.1 263 79 105 140 97 O14578 0 Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21) Homo sapiens (Human) actomyosin structure organization [GO:0031032]; G2/M transition of mitotic cell cycle [GO:0000086]; generation of neurons [GO:0048699]; Golgi organization [GO:0007030]; liver development [GO:0001889]; mitotic cell cycle [GO:0000278]; mitotic cytokinesis [GO:0000281]; negative regulation of hippo signaling [GO:0035331]; neuron apoptotic process [GO:0051402]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of cytokinesis [GO:0032467]; regulation of actin polymerization or depolymerization [GO:0008064] GO:0000086; GO:0000278; GO:0000281; GO:0001223; GO:0001889; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0005856; GO:0007030; GO:0008064; GO:0016020; GO:0017124; GO:0018107; GO:0019901; GO:0030165; GO:0030291; GO:0030496; GO:0031032; GO:0031985; GO:0032154; GO:0032467; GO:0035331; GO:0043025; GO:0046872; GO:0048699; GO:0051402; GO:0097110; GO:0106310 24557 XM_029345131.2 1356 682 486 1060 930 B4JWR9 8.54e-93 NFU1 iron-sulfur cluster scaffold homolog, mitochondrial Drosophila grimshawi (Hawaiian fruit fly) (Idiomyia grimshawi) iron-sulfur cluster assembly [GO:0016226] GO:0005506; GO:0005739; GO:0016226; GO:0051536 24558 XM_029357003.2 134 96 82 93 796 NA NA NA NA NA NA 24559 XM_044328353.1 0 0 0 8 13 NA NA NA NA NA NA 24560 XR_006395861.1 21 7 40 53 44 NA NA NA NA NA NA 24561 XM_029347217.2 150 245 111 221 172 Q2KI24 2.29e-108 Methenyltetrahydrofolate synthase domain-containing protein Bos taurus (Bovine) NA GO:0003723; GO:0005737 24562 XM_029344531.2 0 0 0 19 11 Q5RC69 4.3e-52 Deoxycytidylate deaminase (EC 3.5.4.12) (dCMP deaminase) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) nucleotide biosynthetic process [GO:0009165]; pyrimidine nucleotide metabolic process [GO:0006220] GO:0004132; GO:0006220; GO:0008270; GO:0009165 24563 XM_029334775.2 207 172 108 182 272 Q2TBS2 2.19e-28 39S ribosomal protein L21, mitochondrial (L21mt) (MRP-L21) Bos taurus (Bovine) NA GO:0003735; GO:0005743; GO:0005762 24564 XM_029339954.2 111 127 157 178 266 Q9BSF4 7.93e-28 Mitochondrial import inner membrane translocase subunit Tim29 (TIM29) Homo sapiens (Human) protein insertion into mitochondrial inner membrane [GO:0045039] GO:0005743; GO:0005758; GO:0042721; GO:0045039; GO:0140318 24565 XR_006395144.1 0 44 0 0 0 NA NA NA NA NA NA 24566 XM_044318501.1 17 6 6 0 16 NA NA NA NA NA NA 24567 XM_029340763.2 391 238 30 258 657 P21674 6.57e-38 Follistatin (FS) (Activin-binding protein) Rattus norvegicus (Rat) ameloblast differentiation [GO:0036305]; BMP signaling pathway [GO:0030509]; cell differentiation [GO:0030154]; cellular response to growth factor stimulus [GO:0071363]; female gonad development [GO:0008585]; gamete generation [GO:0007276]; hair follicle morphogenesis [GO:0031069]; hematopoietic progenitor cell differentiation [GO:0002244]; keratinocyte proliferation [GO:0043616]; negative regulation of activin receptor signaling pathway [GO:0032926]; negative regulation of cell differentiation [GO:0045596]; negative regulation of epithelial cell differentiation [GO:0030857]; negative regulation of follicle-stimulating hormone secretion [GO:0046882]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis of dentin-containing tooth [GO:0042475]; pattern specification process [GO:0007389]; positive regulation of hair follicle development [GO:0051798]; regulation of BMP signaling pathway [GO:0030510]; response to organic cyclic compound [GO:0014070]; skeletal system development [GO:0001501] GO:0000122; GO:0001501; GO:0002244; GO:0005615; GO:0005634; GO:0005737; GO:0007276; GO:0007389; GO:0008585; GO:0014070; GO:0030154; GO:0030509; GO:0030510; GO:0030857; GO:0031069; GO:0032926; GO:0036305; GO:0038102; GO:0042475; GO:0043395; GO:0043616; GO:0045596; GO:0046882; GO:0048185; GO:0051798; GO:0071363 24568 XM_029350229.2 0 15 22 145 186 O43182 5.85e-58 Rho GTPase-activating protein 6 (Rho-type GTPase-activating protein 6) (Rho-type GTPase-activating protein RhoGAPX-1) Homo sapiens (Human) actin filament polymerization [GO:0030041]; activation of phospholipase C activity [GO:0007202]; focal adhesion assembly [GO:0048041]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of stress fiber assembly [GO:0051497]; positive regulation of GTPase activity [GO:0043547]; positive regulation of phospholipase activity [GO:0010518]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266] GO:0005096; GO:0005737; GO:0005829; GO:0005884; GO:0007202; GO:0007266; GO:0010518; GO:0015629; GO:0016004; GO:0017124; GO:0030041; GO:0043274; GO:0043547; GO:0048041; GO:0051056; GO:0051497; GO:0051895 24569 XR_006394419.1 50 67 87 27 149 Q5VXM1 1.32e-21 CUB domain-containing protein 2 Homo sapiens (Human) NA GO:0005576 24570 XM_044319105.1 37 126 39 60 85 NA NA NA NA NA NA 24571 XM_029338112.2 37 32 9 12 10 NA NA NA NA NA NA 24572 XR_006398130.1 70 109 0 71 1 NA NA NA NA NA NA 24573 XM_044318279.1 34 21 0 2 122 NA NA NA NA NA NA 24574 XM_029343362.2 26305 23306 14437 29568 29610 Q95209 1e-79 Sortilin-related receptor (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (SorLA-1) (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) Oryctolagus cuniculus (Rabbit) adaptive thermogenesis [GO:1990845]; diet induced thermogenesis [GO:0002024]; endocytosis [GO:0006897]; insulin receptor recycling [GO:0038020]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of triglyceride catabolic process [GO:0010897]; positive regulation of adipose tissue development [GO:1904179]; positive regulation of insulin receptor signaling pathway [GO:0046628]; protein targeting [GO:0006605]; regulation of smooth muscle cell migration [GO:0014910] GO:0000139; GO:0002024; GO:0005615; GO:0005768; GO:0005769; GO:0005771; GO:0005783; GO:0005789; GO:0005794; GO:0005886; GO:0006605; GO:0006897; GO:0010897; GO:0014910; GO:0016020; GO:0030514; GO:0030658; GO:0031901; GO:0032585; GO:0038020; GO:0046628; GO:0055038; GO:1904179; GO:1990845 24575 XM_029350381.2 1056 765 593 990 796 Q9DBU3 5.53e-179 Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) Mus musculus (Mouse) cellular response to dsDNA [GO:1990786]; cellular response to dsRNA [GO:0071359]; cellular response to virus [GO:0098586]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; maturation of SSU-rRNA [GO:0030490]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of MDA-5 signaling pathway [GO:0039534]; negative regulation of protein-containing complex assembly [GO:0031333]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-beta production [GO:0032728]; protein phosphorylation [GO:0006468] GO:0004674; GO:0005524; GO:0005829; GO:0006468; GO:0030490; GO:0030688; GO:0031333; GO:0032728; GO:0039534; GO:0043124; GO:0045087; GO:0045089; GO:0046872; GO:0051607; GO:0071359; GO:0089720; GO:0098586; GO:0106310; GO:1990786 24576 XM_044320241.1 10 7 0 0 0 NA NA NA NA NA NA 24577 XM_029331791.2 74 80 34 61 218 Q6PFL0 8.09e-33 Mediator of RNA polymerase II transcription subunit 27 (Cofactor required for Sp1 transcriptional activation subunit 8) (CRSP complex subunit 8) (Mediator complex subunit 27) Danio rerio (Zebrafish) (Brachydanio rerio) camera-type eye development [GO:0043010]; regulation of transcription by RNA polymerase II [GO:0006357]; retinal cone cell development [GO:0046549] GO:0003713; GO:0006357; GO:0016592; GO:0043010; GO:0046549 24578 XM_029348287.2 37 21 18 51 39 Q9UKT8 2.54e-150 F-box/WD repeat-containing protein 2 (F-box and WD-40 domain-containing protein 2) (Protein MD6) Homo sapiens (Human) protein modification process [GO:0036211]; proteolysis [GO:0006508] GO:0004842; GO:0005829; GO:0006508; GO:0036211 24579 XM_044312515.1 24 0 24 55 111 NA NA NA NA NA NA 24580 XM_029341709.2 534 352 323 442 397 P49321 7.65e-37 Nuclear autoantigenic sperm protein (NASP) Homo sapiens (Human) blastocyst development [GO:0001824]; cell cycle [GO:0007049]; CENP-A containing chromatin assembly [GO:0034080]; DNA replication [GO:0006260]; DNA replication-dependent chromatin assembly [GO:0006335]; male gonad development [GO:0008584]; nucleosome assembly [GO:0006334]; protein transport [GO:0015031]; response to testosterone [GO:0033574] GO:0000785; GO:0001824; GO:0005634; GO:0005654; GO:0005737; GO:0006260; GO:0006334; GO:0006335; GO:0007049; GO:0008584; GO:0015031; GO:0032991; GO:0033574; GO:0034080; GO:0042393; GO:0044877 24581 XR_006391518.1 22 18 8 59 25 NA NA NA NA NA NA 24582 XM_044317087.1 86 169 28 187 202 A7S5D9 2.32e-118 Iodotyrosine deiodinase (EC 1.21.1.1) (Halotyrosine dehalogenase) Nematostella vectensis (Starlet sea anemone) tyrosine metabolic process [GO:0006570] GO:0005886; GO:0006570; GO:0010181; GO:0016491; GO:0140616 24583 XM_029358644.2 0 19 103 0 14 NA NA NA NA NA NA 24584 XM_044320989.1 1289 747 692 1310 1471 P81274 0 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 24585 XM_044317896.1 1699 3054 922 7571 5370 B3EX00 0 Uncharacterized skeletal organic matrix protein 1 (Uncharacterized SOMP-1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 24586 XM_029332435.2 86 93 78 34 299 Q1LZ78 9.64e-52 Cancer-related nucleoside-triphosphatase homolog (NTPase) (EC 3.6.1.15) (Nucleoside triphosphate phosphohydrolase) Bos taurus (Bovine) NA GO:0003924; GO:0005524; GO:0016887; GO:0017111; GO:0043273 24587 XM_029349108.2 437 864 753 953 996 F6R2G2 4.52e-22 NLR family CARD domain-containing protein 4 (Ice protease-activating factor) (Ipaf) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) apoptotic process [GO:0006915]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; regulation of apoptotic process [GO:0042981] GO:0005524; GO:0005829; GO:0006915; GO:0006954; GO:0042981; GO:0045087 24588 XM_029339645.2 438 316 205 384 507 Q6DCT2 0 Armadillo-like helical domain-containing protein 3 Xenopus laevis (African clawed frog) regulation of Golgi organization [GO:1903358] GO:0000139; GO:0005829; GO:1903358 24589 XR_006396452.1 150 115 125 141 170 NA NA NA NA NA NA 24590 XM_044326823.1 10 0 0 0 3 NA NA NA NA NA NA 24591 XM_029345249.2 1563 2859 662 1978 3331 NA NA NA NA NA NA 24592 XM_029343342.2 405 0 73 226 670 Q4U0T9 1.57e-31 Cysteine and glycine-rich protein 3 (Cysteine-rich protein 3) (CRP3) Bos taurus (Bovine) actin cytoskeleton organization [GO:0030036]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac myofibril assembly [GO:0055003]; cellular calcium ion homeostasis [GO:0006874]; detection of muscle stretch [GO:0035995]; glucose homeostasis [GO:0042593]; inflammatory response [GO:0006954]; insulin receptor signaling pathway [GO:0008286]; muscle cell cellular homeostasis [GO:0046716]; muscle organ development [GO:0007517]; muscle tissue development [GO:0060537]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein kinase C signaling [GO:0070528]; protein localization to organelle [GO:0033365]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of the force of heart contraction [GO:0002026]; sarcomere organization [GO:0045214]; T-tubule organization [GO:0033292] GO:0002026; GO:0003300; GO:0003779; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0006874; GO:0006954; GO:0007517; GO:0008286; GO:0008307; GO:0030018; GO:0030036; GO:0031433; GO:0033292; GO:0033365; GO:0035995; GO:0042593; GO:0042802; GO:0042805; GO:0045214; GO:0045944; GO:0046716; GO:0046872; GO:0055003; GO:0060048; GO:0060537; GO:0070528; GO:1903076 24593 XM_029339659.2 184 208 139 179 180 Q9VX98 5.35e-49 Density-regulated protein homolog Drosophila melanogaster (Fruit fly) formation of translation preinitiation complex [GO:0001731]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ecdysone receptor-mediated signaling pathway [GO:0120142]; positive regulation of insulin receptor signaling pathway [GO:0046628]; translation reinitiation [GO:0002188] GO:0001731; GO:0002188; GO:0003729; GO:0003743; GO:0008284; GO:0032991; GO:0046628; GO:0048027; GO:0120142 24594 XM_029358168.2 3000 3067 1547 2629 1798 Q86UC2 2.14e-109 Radial spoke head protein 3 homolog (A-kinase anchor protein RSPH3) (Radial spoke head-like protein 2) Homo sapiens (Human) NA GO:0005737; GO:0005856; GO:0005929 24595 XM_029325919.2 44 15 31 9 63 NA NA NA NA NA NA 24596 XM_029340647.2 528 414 240 573 359 NA NA NA NA NA NA 24597 XM_044329343.1 1219 913 769 883 875 Q9CWG8 4.26e-134 Protein arginine methyltransferase NDUFAF7, mitochondrial (EC 2.1.1.320) (NADH dehydrogenase [ubiquinone] complex I, assembly factor 7) (Protein midA homolog) Mus musculus (Mouse) mitochondrial respiratory chain complex I assembly [GO:0032981]; peptidyl-arginine methylation, to symmetrical-dimethyl arginine [GO:0019918] GO:0005739; GO:0019899; GO:0019918; GO:0032981; GO:0035243 24598 XM_029330544.2 3608 2783 1677 2421 2840 P14733 8.95e-94 Lamin-B1 Mus musculus (Mouse) cellular response to monosodium L-glutamate [GO:1904609]; heterochromatin formation [GO:0031507]; nuclear envelope organization [GO:0006998]; nuclear migration [GO:0007097]; nuclear pore localization [GO:0051664]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of JNK cascade [GO:0046330]; protein localization to nuclear envelope [GO:0090435] GO:0003690; GO:0005200; GO:0005634; GO:0005635; GO:0005637; GO:0005638; GO:0005652; GO:0005654; GO:0005737; GO:0006998; GO:0007097; GO:0008432; GO:0010971; GO:0016363; GO:0031507; GO:0031965; GO:0034399; GO:0043274; GO:0046330; GO:0051664; GO:0090435; GO:1904609; GO:1990837 24599 XM_044320572.1 36 0 0 0 0 NA NA NA NA NA NA 24600 XM_044309508.1 2 1 0 5 9 NA NA NA NA NA NA 24601 XM_029357740.2 1613 1670 1722 1684 2276 Q6AYD3 5.42e-163 Proliferation-associated protein 2G4 Rattus norvegicus (Rat) negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of cell differentiation [GO:0045597]; regulation of translation [GO:0006417]; rRNA processing [GO:0006364] GO:0003676; GO:0003714; GO:0003723; GO:0005634; GO:0005730; GO:0005737; GO:0006364; GO:0006417; GO:0031625; GO:0043066; GO:0045597; GO:0045892; GO:1990904 24602 XM_044324964.1 9 0 0 0 0 Q96AY4 2.7e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24603 XM_044324964.1 9 0 0 0 0 Q96AY4 1.43e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24604 XM_044324964.1 9 0 0 0 0 Q96AY4 7.17e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24605 XM_044324964.1 9 0 0 0 0 Q96AY4 1.19e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24606 XM_044324964.1 9 0 0 0 0 Q96AY4 1.71e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24607 XM_044324964.1 9 0 0 0 0 Q96AY4 6.04e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24608 XM_044324964.1 9 0 0 0 0 Q96AY4 9.08e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24609 XM_044324964.1 9 0 0 0 0 Q96AY4 1.87e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24610 XM_029351816.2 874 805 355 768 285 Q9NYT0 2.46e-52 Pleckstrin-2 Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; intracellular signal transduction [GO:0035556]; positive regulation of plasma membrane bounded cell projection assembly [GO:0120034] GO:0005737; GO:0005856; GO:0005886; GO:0031258; GO:0031532; GO:0032266; GO:0035556; GO:0043325; GO:0080025; GO:0120034 24611 XM_029342244.2 0 110 0 296 0 O15350 1.85e-57 Tumor protein p73 (p53-like transcription factor) (p53-related protein) Homo sapiens (Human) cell cycle [GO:0007049]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of lung ciliated cell differentiation [GO:1901248]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein tetramerization [GO:0051262]; regulation of cell cycle [GO:0051726]; regulation of gene expression [GO:0010468]; regulation of mitotic cell cycle [GO:0007346]; regulation of transcription by RNA polymerase II [GO:0006357]; response to organonitrogen compound [GO:0010243]; response to xenobiotic stimulus [GO:0009410] GO:0000785; GO:0000976; GO:0000978; GO:0000981; GO:0001222; GO:0001228; GO:0001822; GO:0002039; GO:0003700; GO:0005634; GO:0005654; GO:0005794; GO:0005829; GO:0006298; GO:0006357; GO:0006974; GO:0007049; GO:0007346; GO:0008285; GO:0008630; GO:0009410; GO:0010243; GO:0010468; GO:0019901; GO:0030054; GO:0042771; GO:0042802; GO:0043065; GO:0043231; GO:0043410; GO:0045665; GO:0045893; GO:0045944; GO:0046872; GO:0048714; GO:0051262; GO:0051726; GO:0060044; GO:0061629; GO:0097371; GO:0140297; GO:1901248 24612 XM_029343831.2 65 37 56 23 0 NA NA NA NA NA NA 24613 XM_029357662.2 26 1 55 8 105 P07911 2.08e-29 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Homo sapiens (Human) antibacterial innate immune response [GO:0140367]; apoptotic signaling pathway [GO:0097190]; autophagy [GO:0006914]; cellular calcium ion homeostasis [GO:0006874]; cellular chloride ion homeostasis [GO:0030644]; cellular defense response [GO:0006968]; cellular phosphate ion homeostasis [GO:0030643]; cellular response to unfolded protein [GO:0034620]; cellular sodium ion homeostasis [GO:0006883]; chaperone-mediated protein folding [GO:0061077]; citric acid secretion [GO:0046720]; collecting duct development [GO:0072044]; connective tissue replacement [GO:0097709]; creatinine homeostasis [GO:0097273]; defense response to Gram-negative bacterium [GO:0050829]; endoplasmic reticulum organization [GO:0007029]; glomerular filtration [GO:0003094]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; juxtaglomerular apparatus development [GO:0072051]; leukocyte cell-cell adhesion [GO:0007159]; lipid metabolic process [GO:0006629]; metanephric ascending thin limb development [GO:0072218]; metanephric distal convoluted tubule development [GO:0072221]; metanephric thick ascending limb development [GO:0072233]; micturition [GO:0060073]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell population proliferation [GO:0008285]; neutrophil migration [GO:1990266]; organ or tissue specific immune response [GO:0002251]; peptidyl-threonine phosphorylation [GO:0018107]; potassium ion homeostasis [GO:0055075]; protein localization to vacuole [GO:0072665]; protein transport into plasma membrane raft [GO:0044861]; regulation of blood pressure [GO:0008217]; regulation of protein transport [GO:0051223]; regulation of urine volume [GO:0035809]; renal sodium ion absorption [GO:0070294]; renal urate salt excretion [GO:0097744]; renal water homeostasis [GO:0003091]; response to lipopolysaccharide [GO:0032496]; response to water deprivation [GO:0009414]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; ubiquitin-dependent ERAD pathway [GO:0030433]; urate transport [GO:0015747]; urea transmembrane transport [GO:0071918] GO:0000922; GO:0002251; GO:0003091; GO:0003094; GO:0005201; GO:0005509; GO:0005615; GO:0005783; GO:0005796; GO:0005929; GO:0006629; GO:0006874; GO:0006883; GO:0006914; GO:0006954; GO:0006968; GO:0007029; GO:0007157; GO:0007159; GO:0008217; GO:0008285; GO:0008380; GO:0009410; GO:0009414; GO:0009986; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0018107; GO:0019864; GO:0019898; GO:0030433; GO:0030643; GO:0030644; GO:0032496; GO:0033209; GO:0033555; GO:0034620; GO:0035809; GO:0044861; GO:0046720; GO:0050829; GO:0051223; GO:0055075; GO:0060073; GO:0060170; GO:0061077; GO:0070062; GO:0070294; GO:0071918; GO:0072044; GO:0072051; GO:0072218; GO:0072221; GO:0072233; GO:0072665; GO:0097190; GO:0097273; GO:0097709; GO:0097744; GO:0140367; GO:1990266 24614 XM_029324994.2 8 0 0 0 50 NA NA NA NA NA NA 24615 XM_044318519.1 0 1 49 0 0 P0CI65 9.26e-52 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 24616 XM_044318519.1 0 1 49 0 0 P0CI65 1.48e-49 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 24617 XM_044318519.1 0 1 49 0 0 P0CI65 2.75e-49 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 24618 XM_044318519.1 0 1 49 0 0 P0CI65 5.59e-49 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 24619 XM_044318519.1 0 1 49 0 0 P0CI65 1.8e-46 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 24620 XM_044318519.1 0 1 49 0 0 P0CI65 1.93e-46 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 24621 XM_044318519.1 0 1 49 0 0 P0CI65 2.11e-42 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 24622 XM_044318519.1 0 1 49 0 0 P0CI65 4.2e-38 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 24623 XM_029339725.2 125 193 0 146 23 NA NA NA NA NA NA 24624 XM_044323467.1 9 1 77 30 119 NA NA NA NA NA NA 24625 XM_044321802.1 0 0 6 0 0 NA NA NA NA NA NA 24626 XM_044323863.1 8196 6406 6007 8024 7219 Q5ZIR1 1.62e-109 Endophilin-B1 (SH3 domain-containing GRB2-like protein B1) Gallus gallus (Chicken) apoptotic process [GO:0006915]; membrane organization [GO:0061024] GO:0000139; GO:0005741; GO:0006915; GO:0008289; GO:0016020; GO:0061024 24627 XM_044309682.1 0 7 19 9 7 NA NA NA NA NA NA 24628 XM_029345652.2 30 14 24 9 84 NA NA NA NA NA NA 24629 XR_003827952.2 11 22 26 50 10 NA NA NA NA NA NA 24630 XM_044313342.1 0 0 0 0 14 NA NA NA NA NA NA 24631 XM_029346929.2 11915 17082 13286 15215 14483 P33947 2.37e-120 ER lumen protein-retaining receptor 2 (ERD2-like protein 1) (ELP-1) (KDEL endoplasmic reticulum protein retention receptor 2) (KDEL receptor 2) Homo sapiens (Human) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; protein retention in ER lumen [GO:0006621]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] GO:0000139; GO:0005046; GO:0005783; GO:0005789; GO:0005801; GO:0006621; GO:0006888; GO:0006890; GO:0015031; GO:0016020; GO:0030133; GO:0030663; GO:0035437; GO:0046923 24632 XM_044312397.1 71 15 10 63 66 NA NA NA NA NA NA 24633 XM_044308877.1 8 0 1 0 18 NA NA NA NA NA NA 24634 XM_044310300.1 151 9 104 81 73 Q96AY4 7.46e-112 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24635 XM_044310300.1 151 9 104 81 73 Q96AY4 5.61e-108 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24636 XM_044310300.1 151 9 104 81 73 Q96AY4 2.24e-107 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24637 XM_044310300.1 151 9 104 81 73 Q96AY4 1.19e-94 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24638 XM_044310300.1 151 9 104 81 73 Q96AY4 6.45e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24639 XM_044310300.1 151 9 104 81 73 Q96AY4 2.58e-60 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24640 XM_044310300.1 151 9 104 81 73 Q96AY4 1.35e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24641 XM_029347097.2 0 8 10 0 12 NA NA NA NA NA NA 24642 XM_029358529.2 20 14 27 48 39 NA NA NA NA NA NA 24643 XM_044308134.1 431 222 277 492 415 Q8WXX0 0 Dynein axonemal heavy chain 7 (Axonemal beta dynein heavy chain 7) (Ciliary dynein heavy chain 7) (Dynein heavy chain-like protein 2) (hDHC2) Homo sapiens (Human) cilium movement [GO:0003341]; cilium-dependent cell motility [GO:0060285]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018] GO:0003341; GO:0003777; GO:0005509; GO:0005524; GO:0005829; GO:0005858; GO:0005874; GO:0005929; GO:0007018; GO:0008569; GO:0030286; GO:0036156; GO:0036159; GO:0045505; GO:0051959; GO:0060285 24644 XM_029338379.2 1696 1263 895 1828 1674 Q499P8 8.86e-92 RUS family member 1 Rattus norvegicus (Rat) NA GO:0016020 24645 XM_044313286.1 42 0 27 29 58 NA NA NA NA NA NA 24646 XM_044313186.1 2 0 2 3 26 NA NA NA NA NA NA 24647 XR_006393877.1 375 104 388 278 928 NA NA NA NA NA NA 24648 XM_029332734.2 312 86 243 447 340 Q9NUN7 2.89e-49 Alkaline ceramidase 3 (AlkCDase 3) (Alkaline CDase 3) (EC 3.5.1.-) (EC 3.5.1.23) (Alkaline dihydroceramidase SB89) (Alkaline phytoceramidase) (aPHC) Homo sapiens (Human) ceramide catabolic process [GO:0046514]; inflammatory response [GO:0006954]; myelination [GO:0042552]; phytosphingosine biosynthetic process [GO:0071602]; positive regulation of cell population proliferation [GO:0008284]; regulation of programmed cell death [GO:0043067]; sphingolipid biosynthetic process [GO:0030148]; sphingosine biosynthetic process [GO:0046512] GO:0000139; GO:0005509; GO:0005789; GO:0006954; GO:0008270; GO:0008284; GO:0016020; GO:0017040; GO:0030148; GO:0042552; GO:0043067; GO:0046512; GO:0046514; GO:0070774; GO:0071602; GO:0071633; GO:0102121 24649 XM_044312271.1 81 67 0 238 204 NA NA NA NA NA NA 24650 XR_003828496.2 266 260 91 287 96 NA NA NA NA NA NA 24651 XM_029327760.2 0 0 0 85 0 NA NA NA NA NA NA 24652 XM_029344679.2 26 11 0 32 0 Q5R634 1.7e-38 Divergent protein kinase domain 1A (Protein FAM69A) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0005789 24653 XM_044321068.1 1114 1201 985 1698 2130 Q3ZCL5 1.33e-89 Arfaptin-2 (ADP-ribosylation factor-interacting protein 2) Bos taurus (Bovine) intracellular protein transport [GO:0006886]; mitophagy [GO:0000423]; protein localization to phagophore assembly site [GO:0034497]; regulation of Arp2/3 complex-mediated actin nucleation [GO:0034315] GO:0000423; GO:0005543; GO:0006886; GO:0019904; GO:0032588; GO:0034315; GO:0034497 24654 XM_029353614.2 36 0 0 0 0 P25931 1.68e-23 RYamide receptor (Neuropeptide Y-like receptor) (NPY-R) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218] GO:0001653; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0016020 24655 XR_006395714.1 0 0 16 2 40 NA NA NA NA NA NA 24656 XM_044316109.1 8 0 2 3 0 Q9TXJ8 2.72e-21 Putative ATP-dependent DNA helicase Q1 (EC 3.6.4.12) Caenorhabditis elegans DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724] GO:0000724; GO:0003676; GO:0005524; GO:0005634; GO:0005694; GO:0005737; GO:0006268; GO:0006281; GO:0006310; GO:0009378; GO:0016887; GO:0032508; GO:0043138 24657 XM_044309466.1 318 266 195 0 0 Q9JKL7 3.71e-38 Splicing regulatory glutamine/lysine-rich protein 1 (SR-related protein of 86 kDa) (Serine/arginine-rich-splicing regulatory protein 86) (SRrp86) (Splicing factor, arginine/serine-rich 12) Rattus norvegicus (Rat) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0003723; GO:0005654; GO:0005681; GO:0006397; GO:0008380 24658 XR_003825229.2 76 119 20 69 68 NA NA NA NA NA NA 24659 XM_029326819.2 9 5 25 13 4 NA NA NA NA NA NA 24660 XM_044326745.1 35 6 10 45 7 NA NA NA NA NA NA 24661 XM_029343621.2 9 15 6 0 49 A9Y006 1.39e-76 Aquaporin-3 (Aquaglyceroporin-3) Sus scrofa (Pig) glycerol transmembrane transport [GO:0015793]; polyol transmembrane transport [GO:0015791]; water transport [GO:0006833] GO:0005886; GO:0006833; GO:0015166; GO:0015204; GO:0015250; GO:0015254; GO:0015791; GO:0015793; GO:0016323 24662 XM_044309079.1 36 16 14 2 6 NA NA NA NA NA NA 24663 XM_029324852.2 408 633 154 344 565 Q6P3R8 4.3e-76 Serine/threonine-protein kinase Nek5 (EC 2.7.11.1) (Never in mitosis A-related kinase 5) (NimA-related protein kinase 5) Homo sapiens (Human) protein phosphorylation [GO:0006468] GO:0004672; GO:0004674; GO:0005524; GO:0006468; GO:0046872; GO:0106310 24664 XM_044327023.1 594 291 300 345 1540 NA NA NA NA NA NA 24665 XM_044307206.1 2498 1915 1845 2641 2230 Q8BH73 4.33e-80 Glutaminyl-peptide cyclotransferase-like protein (EC 2.3.2.5) (Golgi-resident glutaminyl-peptide cyclotransferase) (isoQC) (gQC) Mus musculus (Mouse) peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase [GO:0017186] GO:0000139; GO:0005794; GO:0008270; GO:0016603; GO:0017186 24666 XM_044307223.1 530 135 333 557 730 B3EWY9 0 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 24667 XM_029349592.2 1037 1559 942 1394 1024 Q8WNR0 8.61e-23 High affinity copper uptake protein 1 (Copper transporter 1) (CTR1) (Solute carrier family 31 member 1) Sus scrofa (Pig) cellular copper ion homeostasis [GO:0006878]; copper ion import [GO:0015677]; establishment of localization in cell [GO:0051649] GO:0005375; GO:0005770; GO:0005886; GO:0006878; GO:0014704; GO:0015677; GO:0042802; GO:0051649; GO:0055037 24668 XM_044317827.1 20658 14674 14731 28607 28096 Q9QXZ0 0 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4 (Actin cross-linking family 7) Mus musculus (Mouse) establishment or maintenance of cell polarity [GO:0007163]; Golgi to plasma membrane protein transport [GO:0043001]; intermediate filament cytoskeleton organization [GO:0045104]; mesoderm formation [GO:0001707]; positive regulation of axon extension [GO:0045773]; positive regulation of Wnt signaling pathway [GO:0030177]; post-translational protein targeting to endoplasmic reticulum membrane [GO:0006620]; protein localization [GO:0008104]; regulation of cell migration [GO:0030334]; regulation of epithelial cell migration [GO:0010632]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule-based process [GO:0032886]; regulation of neuron projection arborization [GO:0150011]; Wnt signaling pathway [GO:0016055]; wound healing [GO:0042060] GO:0001707; GO:0003779; GO:0005198; GO:0005509; GO:0005737; GO:0005794; GO:0005874; GO:0005886; GO:0005938; GO:0006620; GO:0007163; GO:0008017; GO:0008104; GO:0010632; GO:0014069; GO:0015629; GO:0015630; GO:0016020; GO:0016055; GO:0016887; GO:0030177; GO:0030334; GO:0032587; GO:0032886; GO:0042060; GO:0043001; GO:0045104; GO:0045773; GO:0051011; GO:0051015; GO:0051893; GO:0150011 24669 XM_044317827.1 20658 14674 14731 28607 28096 Q9QXZ0 4.71e-144 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4 (Actin cross-linking family 7) Mus musculus (Mouse) establishment or maintenance of cell polarity [GO:0007163]; Golgi to plasma membrane protein transport [GO:0043001]; intermediate filament cytoskeleton organization [GO:0045104]; mesoderm formation [GO:0001707]; positive regulation of axon extension [GO:0045773]; positive regulation of Wnt signaling pathway [GO:0030177]; post-translational protein targeting to endoplasmic reticulum membrane [GO:0006620]; protein localization [GO:0008104]; regulation of cell migration [GO:0030334]; regulation of epithelial cell migration [GO:0010632]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule-based process [GO:0032886]; regulation of neuron projection arborization [GO:0150011]; Wnt signaling pathway [GO:0016055]; wound healing [GO:0042060] GO:0001707; GO:0003779; GO:0005198; GO:0005509; GO:0005737; GO:0005794; GO:0005874; GO:0005886; GO:0005938; GO:0006620; GO:0007163; GO:0008017; GO:0008104; GO:0010632; GO:0014069; GO:0015629; GO:0015630; GO:0016020; GO:0016055; GO:0016887; GO:0030177; GO:0030334; GO:0032587; GO:0032886; GO:0042060; GO:0043001; GO:0045104; GO:0045773; GO:0051011; GO:0051015; GO:0051893; GO:0150011 24670 XM_044317827.1 20658 14674 14731 28607 28096 Q9QXZ0 8.32e-74 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4 (Actin cross-linking family 7) Mus musculus (Mouse) establishment or maintenance of cell polarity [GO:0007163]; Golgi to plasma membrane protein transport [GO:0043001]; intermediate filament cytoskeleton organization [GO:0045104]; mesoderm formation [GO:0001707]; positive regulation of axon extension [GO:0045773]; positive regulation of Wnt signaling pathway [GO:0030177]; post-translational protein targeting to endoplasmic reticulum membrane [GO:0006620]; protein localization [GO:0008104]; regulation of cell migration [GO:0030334]; regulation of epithelial cell migration [GO:0010632]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule-based process [GO:0032886]; regulation of neuron projection arborization [GO:0150011]; Wnt signaling pathway [GO:0016055]; wound healing [GO:0042060] GO:0001707; GO:0003779; GO:0005198; GO:0005509; GO:0005737; GO:0005794; GO:0005874; GO:0005886; GO:0005938; GO:0006620; GO:0007163; GO:0008017; GO:0008104; GO:0010632; GO:0014069; GO:0015629; GO:0015630; GO:0016020; GO:0016055; GO:0016887; GO:0030177; GO:0030334; GO:0032587; GO:0032886; GO:0042060; GO:0043001; GO:0045104; GO:0045773; GO:0051011; GO:0051015; GO:0051893; GO:0150011 24671 XM_044317827.1 20658 14674 14731 28607 28096 Q9QXZ0 3.33e-48 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4 (Actin cross-linking family 7) Mus musculus (Mouse) establishment or maintenance of cell polarity [GO:0007163]; Golgi to plasma membrane protein transport [GO:0043001]; intermediate filament cytoskeleton organization [GO:0045104]; mesoderm formation [GO:0001707]; positive regulation of axon extension [GO:0045773]; positive regulation of Wnt signaling pathway [GO:0030177]; post-translational protein targeting to endoplasmic reticulum membrane [GO:0006620]; protein localization [GO:0008104]; regulation of cell migration [GO:0030334]; regulation of epithelial cell migration [GO:0010632]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule-based process [GO:0032886]; regulation of neuron projection arborization [GO:0150011]; Wnt signaling pathway [GO:0016055]; wound healing [GO:0042060] GO:0001707; GO:0003779; GO:0005198; GO:0005509; GO:0005737; GO:0005794; GO:0005874; GO:0005886; GO:0005938; GO:0006620; GO:0007163; GO:0008017; GO:0008104; GO:0010632; GO:0014069; GO:0015629; GO:0015630; GO:0016020; GO:0016055; GO:0016887; GO:0030177; GO:0030334; GO:0032587; GO:0032886; GO:0042060; GO:0043001; GO:0045104; GO:0045773; GO:0051011; GO:0051015; GO:0051893; GO:0150011 24672 XM_044317827.1 20658 14674 14731 28607 28096 Q9QXZ0 6.18e-44 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4 (Actin cross-linking family 7) Mus musculus (Mouse) establishment or maintenance of cell polarity [GO:0007163]; Golgi to plasma membrane protein transport [GO:0043001]; intermediate filament cytoskeleton organization [GO:0045104]; mesoderm formation [GO:0001707]; positive regulation of axon extension [GO:0045773]; positive regulation of Wnt signaling pathway [GO:0030177]; post-translational protein targeting to endoplasmic reticulum membrane [GO:0006620]; protein localization [GO:0008104]; regulation of cell migration [GO:0030334]; regulation of epithelial cell migration [GO:0010632]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule-based process [GO:0032886]; regulation of neuron projection arborization [GO:0150011]; Wnt signaling pathway [GO:0016055]; wound healing [GO:0042060] GO:0001707; GO:0003779; GO:0005198; GO:0005509; GO:0005737; GO:0005794; GO:0005874; GO:0005886; GO:0005938; GO:0006620; GO:0007163; GO:0008017; GO:0008104; GO:0010632; GO:0014069; GO:0015629; GO:0015630; GO:0016020; GO:0016055; GO:0016887; GO:0030177; GO:0030334; GO:0032587; GO:0032886; GO:0042060; GO:0043001; GO:0045104; GO:0045773; GO:0051011; GO:0051015; GO:0051893; GO:0150011 24673 XM_044317827.1 20658 14674 14731 28607 28096 Q9QXZ0 1.13e-25 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4 (Actin cross-linking family 7) Mus musculus (Mouse) establishment or maintenance of cell polarity [GO:0007163]; Golgi to plasma membrane protein transport [GO:0043001]; intermediate filament cytoskeleton organization [GO:0045104]; mesoderm formation [GO:0001707]; positive regulation of axon extension [GO:0045773]; positive regulation of Wnt signaling pathway [GO:0030177]; post-translational protein targeting to endoplasmic reticulum membrane [GO:0006620]; protein localization [GO:0008104]; regulation of cell migration [GO:0030334]; regulation of epithelial cell migration [GO:0010632]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule-based process [GO:0032886]; regulation of neuron projection arborization [GO:0150011]; Wnt signaling pathway [GO:0016055]; wound healing [GO:0042060] GO:0001707; GO:0003779; GO:0005198; GO:0005509; GO:0005737; GO:0005794; GO:0005874; GO:0005886; GO:0005938; GO:0006620; GO:0007163; GO:0008017; GO:0008104; GO:0010632; GO:0014069; GO:0015629; GO:0015630; GO:0016020; GO:0016055; GO:0016887; GO:0030177; GO:0030334; GO:0032587; GO:0032886; GO:0042060; GO:0043001; GO:0045104; GO:0045773; GO:0051011; GO:0051015; GO:0051893; GO:0150011 24674 XM_044317827.1 20658 14674 14731 28607 28096 Q9QXZ0 1.46e-25 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4 (Actin cross-linking family 7) Mus musculus (Mouse) establishment or maintenance of cell polarity [GO:0007163]; Golgi to plasma membrane protein transport [GO:0043001]; intermediate filament cytoskeleton organization [GO:0045104]; mesoderm formation [GO:0001707]; positive regulation of axon extension [GO:0045773]; positive regulation of Wnt signaling pathway [GO:0030177]; post-translational protein targeting to endoplasmic reticulum membrane [GO:0006620]; protein localization [GO:0008104]; regulation of cell migration [GO:0030334]; regulation of epithelial cell migration [GO:0010632]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule-based process [GO:0032886]; regulation of neuron projection arborization [GO:0150011]; Wnt signaling pathway [GO:0016055]; wound healing [GO:0042060] GO:0001707; GO:0003779; GO:0005198; GO:0005509; GO:0005737; GO:0005794; GO:0005874; GO:0005886; GO:0005938; GO:0006620; GO:0007163; GO:0008017; GO:0008104; GO:0010632; GO:0014069; GO:0015629; GO:0015630; GO:0016020; GO:0016055; GO:0016887; GO:0030177; GO:0030334; GO:0032587; GO:0032886; GO:0042060; GO:0043001; GO:0045104; GO:0045773; GO:0051011; GO:0051015; GO:0051893; GO:0150011 24675 XR_003823068.2 274 83 191 288 302 NA NA NA NA NA NA 24676 XM_029349731.2 446 305 203 137 668 Q6PBT5 5.35e-153 Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 (EC 1.8.1.-) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005634; GO:0016491; GO:0030017; GO:0050660 24677 XM_044317721.1 54 38 29 47 42 NA NA NA NA NA NA 24678 XR_006393396.1 18 14 50 28 108 NA NA NA NA NA NA 24679 XM_029357413.2 0 0 0 92 0 Q9WV18 2.05e-57 Gamma-aminobutyric acid type B receptor subunit 1 (GABA-B receptor 1) (GABA-B-R1) (GABA-BR1) (GABABR1) (Gb1) Mus musculus (Mouse) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of dopamine secretion [GO:0033602]; negative regulation of epinephrine secretion [GO:0032811]; negative regulation of gamma-aminobutyric acid secretion [GO:0014053]; negative regulation of synaptic transmission [GO:0050805]; neuron-glial cell signaling [GO:0150099]; osteoblast differentiation [GO:0001649]; positive regulation of glutamate secretion [GO:0014049]; positive regulation of growth hormone secretion [GO:0060124]; regulation of glutamate secretion [GO:0014048]; response to ethanol [GO:0045471]; response to nicotine [GO:0035094]; synaptic transmission, GABAergic [GO:0051932] GO:0001649; GO:0004888; GO:0004965; GO:0005615; GO:0005737; GO:0005789; GO:0005886; GO:0007193; GO:0007194; GO:0007214; GO:0008021; GO:0008285; GO:0014048; GO:0014049; GO:0014053; GO:0016020; GO:0030673; GO:0031966; GO:0032811; GO:0033602; GO:0035094; GO:0038037; GO:0038039; GO:0042734; GO:0043005; GO:0043025; GO:0043197; GO:0043198; GO:0043231; GO:0045121; GO:0045211; GO:0045471; GO:0046982; GO:0050805; GO:0051932; GO:0060124; GO:0097060; GO:0098685; GO:0098793; GO:0098978; GO:0098982; GO:0099579; GO:0150047; GO:0150099; GO:1902710; GO:1902712; GO:1990430 24680 XM_044319526.1 79 426 151 82 81 B5DF45 1.86e-104 TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6) Rattus norvegicus (Rat) activation of NF-kappaB-inducing kinase activity [GO:0007250]; activation of protein kinase activity [GO:0032147]; animal organ morphogenesis [GO:0009887]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; bone remodeling [GO:0046849]; bone resorption [GO:0045453]; cell development [GO:0048468]; cellular response to cytokine stimulus [GO:0071345]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-17-mediated signaling pathway [GO:0097400]; JNK cascade [GO:0007254]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin production [GO:0002637]; response to interleukin-1 [GO:0070555]; response to ischemia [GO:0002931]; signal transduction [GO:0007165]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000122; GO:0000209; GO:0001503; GO:0001701; GO:0001843; GO:0002637; GO:0002726; GO:0002931; GO:0004842; GO:0005164; GO:0005634; GO:0005737; GO:0005811; GO:0005829; GO:0005886; GO:0005938; GO:0006955; GO:0006974; GO:0007165; GO:0007249; GO:0007250; GO:0007254; GO:0008270; GO:0009887; GO:0009898; GO:0016567; GO:0019221; GO:0019886; GO:0019901; GO:0030316; GO:0031435; GO:0031624; GO:0031625; GO:0031666; GO:0031996; GO:0032147; GO:0032735; GO:0032743; GO:0032755; GO:0032813; GO:0032991; GO:0033209; GO:0035631; GO:0042088; GO:0042102; GO:0042475; GO:0042802; GO:0042826; GO:0042981; GO:0043011; GO:0043122; GO:0043123; GO:0043422; GO:0043507; GO:0045453; GO:0045672; GO:0045892; GO:0045944; GO:0046330; GO:0046849; GO:0047485; GO:0048468; GO:0048471; GO:0048661; GO:0050852; GO:0051091; GO:0051092; GO:0051865; GO:0061630; GO:0070498; GO:0070534; GO:0070555; GO:0071222; GO:0071345; GO:0097400; GO:1901224; GO:1904996; GO:2000679 24681 XM_029346501.2 4606 2688 2998 3521 3348 P23049 2.14e-55 Tyrosine-protein kinase transforming protein SEA (EC 2.7.10.2) Avian erythroblastosis virus (strain S13) NA GO:0004715; GO:0005524 24682 XM_029357380.2 373 362 265 504 79 Q9VUL9 8.09e-39 Glycoprotein 3-alpha-L-fucosyltransferase A (EC 2.4.1.214) (Core alpha-(1,3)-fucosyltransferase) Drosophila melanogaster (Fruit fly) fucosylation [GO:0036065]; N-glycan fucosylation [GO:0036071]; nervous system development [GO:0007399]; protein glycosylation [GO:0006486] GO:0005797; GO:0006486; GO:0007399; GO:0008417; GO:0018392; GO:0032580; GO:0036065; GO:0036071; GO:0046920 24683 XM_029345347.2 44 13 20 14 44 Q9EQD2 2.15e-28 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 24684 XM_029330419.2 0 0 0 0 31 Q9EQD2 9.56e-38 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 24685 XM_029343683.2 108 15 11 8 6 NA NA NA NA NA NA 24686 XM_029330452.2 1107 508 309 625 518 Q6DF08 0 UDP-glucuronic acid decarboxylase 1 (EC 4.1.1.35) (UDP-glucuronate decarboxylase 1) (UXS-1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) D-xylose metabolic process [GO:0042732]; UDP-D-xylose biosynthetic process [GO:0033320] GO:0032580; GO:0033320; GO:0042732; GO:0048040; GO:0070403 24687 XM_044309666.1 207 87 142 131 448 O16025 0 Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (AOS) (EC 4.2.1.-) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)] Plexaura homomalla (Black sea rod) arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; lipid oxidation [GO:0034440]; oxylipin biosynthetic process [GO:0031408] GO:0005506; GO:0005737; GO:0006633; GO:0009978; GO:0016020; GO:0019369; GO:0020037; GO:0031408; GO:0034440; GO:0047677 24688 XR_006396065.1 6 6 0 25 0 NA NA NA NA NA NA 24689 XR_006391912.1 297 176 182 153 230 NA NA NA NA NA NA 24690 XM_029346076.2 1790 3688 1014 1043 634 Q8K4M5 7.72e-54 COMM domain-containing protein 1 (Protein Murr1) Mus musculus (Mouse) cellular copper ion homeostasis [GO:0006878]; cholesterol homeostasis [GO:0042632]; copper ion homeostasis [GO:0055070]; Golgi to plasma membrane transport [GO:0006893]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of hypoxia-inducible factor-1alpha signaling pathway [GO:1902072]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of protein localization to cell surface [GO:2000009]; negative regulation of sodium ion transmembrane transport [GO:1902306]; nucleotide-excision repair [GO:0006289]; plasma membrane to endosome transport [GO:0048227]; positive regulation of cholesterol import [GO:1904109]; positive regulation of endosome to plasma membrane protein transport [GO:1905751]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein ubiquitination [GO:0031398]; protein destabilization [GO:0031648]; protein localization to cell surface [GO:0034394]; protein transport [GO:0015031]; regulation of plasma lipoprotein particle levels [GO:0097006]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434] GO:0005507; GO:0005546; GO:0005547; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005829; GO:0006289; GO:0006878; GO:0006893; GO:0010008; GO:0015031; GO:0019871; GO:0031398; GO:0031462; GO:0031648; GO:0032088; GO:0032434; GO:0034383; GO:0034394; GO:0042632; GO:0042802; GO:0042803; GO:0043325; GO:0048227; GO:0050750; GO:0055037; GO:0055070; GO:0070300; GO:0080025; GO:0097006; GO:1902072; GO:1902306; GO:1904109; GO:1905751; GO:2000009; GO:2000010 24691 XM_029332626.2 1509 4 3 1011 125 Q8IUR6 1.7e-34 CREB3 regulatory factor (Luman recruitment factor) (LRF) Homo sapiens (Human) negative regulation of endoplasmic reticulum unfolded protein response [GO:1900102]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of intracellular transport [GO:0032388]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein transport [GO:0051222]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; response to endoplasmic reticulum stress [GO:0034976]; response to unfolded protein [GO:0006986] GO:0000122; GO:0000977; GO:0000981; GO:0001228; GO:0005634; GO:0005654; GO:0005737; GO:0006357; GO:0006986; GO:0016604; GO:0032388; GO:0034976; GO:0045732; GO:0045944; GO:0051222; GO:1900102 24692 XM_044311043.1 1 0 2 11 0 NA NA NA NA NA NA 24693 XM_044326799.1 29 21 2 10 35 NA NA NA NA NA NA 24694 XR_006391999.1 189 49 35 24 62 NA NA NA NA NA NA 24695 XM_029357673.2 582 167 103 74 105 NA NA NA NA NA NA 24696 XM_044309649.1 0 0 91 0 81 A0A3M6TIF0 9.14e-153 NA NA NA NA 24697 XR_006394457.1 1 5 8 1 2 NA NA NA NA NA NA 24698 XM_029335378.2 18 6 8 21 56 NA NA NA NA NA NA 24699 XM_044311436.1 30 6 14 0 18 NA NA NA NA NA NA 24700 XM_044325427.1 22 7 13 29 26 NA NA NA NA NA NA 24701 XM_029357837.2 263 314 258 238 156 NA NA NA NA NA NA 24702 XM_029327991.2 37 137 117 136 78 Q96DM1 2.78e-55 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 24703 XM_044321058.1 807 364 444 357 423 P53370 1.74e-64 Nucleoside diphosphate-linked moiety X motif 6 (Nudix motif 6) (EC 3.6.1.-) (Antisense basic fibroblast growth factor) (Protein GFG) Homo sapiens (Human) negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285] GO:0005634; GO:0005737; GO:0005739; GO:0008285; GO:0035529; GO:0045786; GO:0047631; GO:0051287 24704 XM_044316265.1 1 2 0 16 16 NA NA NA NA NA NA 24705 XM_044324490.1 564 575 739 475 704 Q6P8J2 6.56e-45 Thialysine N-epsilon-acetyltransferase (EC 2.3.1.-) (Diamine acetyltransferase 2) (EC 2.3.1.57) (Spermidine/spermine N(1)-acetyltransferase 2) (SSAT-2) Mus musculus (Mouse) nor-spermidine metabolic process [GO:0046204]; putrescine acetylation [GO:0032920]; spermidine acetylation [GO:0032918]; spermidine metabolic process [GO:0008216]; spermine acetylation [GO:0032919]; spermine metabolic process [GO:0008215] GO:0004145; GO:0005737; GO:0008080; GO:0008215; GO:0008216; GO:0019809; GO:0032918; GO:0032919; GO:0032920; GO:0042802; GO:0046204 24706 XM_044319184.1 2263 839 410 3025 1335 NA NA NA NA NA NA 24707 XM_029353787.2 864 435 397 734 932 Q5PPZ5 2.46e-51 Bridging integrator 3 homolog Xenopus laevis (African clawed frog) actin cortical patch localization [GO:0051666]; division septum assembly [GO:0000917]; endocytosis [GO:0006897] GO:0000917; GO:0005737; GO:0005856; GO:0006897; GO:0051666 24708 XR_006398063.1 23 0 31 6 86 NA NA NA NA NA NA 24709 XM_029355976.2 416 486 263 522 727 NA NA NA NA NA NA 24710 XM_044307414.1 819 2552 2484 5593 833 Q95P04 2.03e-162 GFP-like non-fluorescent chromoprotein (gtCP) Goniopora tenuidens (Anemone coral) (Rhodaraea tenuidens) bioluminescence [GO:0008218] GO:0008218 24711 XM_044322356.1 7 6 7 13 8 NA NA NA NA NA NA 24712 XM_044316399.1 1 74 35 123 158 NA NA NA NA NA NA 24713 XM_029349873.2 2195 1883 1149 1514 1274 Q5ZL16 0 WD repeat domain phosphoinositide-interacting protein 3 (WIPI-3) (WD repeat-containing protein 45B) Gallus gallus (Chicken) autophagosome assembly [GO:0000045]; autophagy of mitochondrion [GO:0000422]; autophagy of nucleus [GO:0044804]; cellular response to starvation [GO:0009267]; protein lipidation [GO:0006497]; protein localization to phagophore assembly site [GO:0034497] GO:0000045; GO:0000407; GO:0000422; GO:0005764; GO:0005829; GO:0006497; GO:0009267; GO:0019898; GO:0032266; GO:0034045; GO:0034497; GO:0044804; GO:0080025 24714 XM_044323793.1 40 14 75 72 45 NA NA NA NA NA NA 24715 XR_006391320.1 5050 2562 1967 3344 3281 Q2VLG4 2.59e-65 Scavenger receptor cysteine-rich type 1 protein M130 (CD antigen CD163) [Cleaved into: Soluble CD163 (sCD163)] Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops) acute-phase response [GO:0006953] GO:0005044; GO:0005576; GO:0005886; GO:0006953 24716 XR_006391320.1 5050 2562 1967 3344 3281 Q2VLG4 2.04e-33 Scavenger receptor cysteine-rich type 1 protein M130 (CD antigen CD163) [Cleaved into: Soluble CD163 (sCD163)] Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops) acute-phase response [GO:0006953] GO:0005044; GO:0005576; GO:0005886; GO:0006953 24717 XR_006391320.1 5050 2562 1967 3344 3281 Q2VLG4 4.07e-33 Scavenger receptor cysteine-rich type 1 protein M130 (CD antigen CD163) [Cleaved into: Soluble CD163 (sCD163)] Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops) acute-phase response [GO:0006953] GO:0005044; GO:0005576; GO:0005886; GO:0006953 24718 XR_006391320.1 5050 2562 1967 3344 3281 Q2VLG4 2.08e-32 Scavenger receptor cysteine-rich type 1 protein M130 (CD antigen CD163) [Cleaved into: Soluble CD163 (sCD163)] Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops) acute-phase response [GO:0006953] GO:0005044; GO:0005576; GO:0005886; GO:0006953 24719 XR_006391320.1 5050 2562 1967 3344 3281 Q2VLG4 1.83e-23 Scavenger receptor cysteine-rich type 1 protein M130 (CD antigen CD163) [Cleaved into: Soluble CD163 (sCD163)] Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops) acute-phase response [GO:0006953] GO:0005044; GO:0005576; GO:0005886; GO:0006953 24720 XR_006391320.1 5050 2562 1967 3344 3281 Q2VLG4 3.56e-23 Scavenger receptor cysteine-rich type 1 protein M130 (CD antigen CD163) [Cleaved into: Soluble CD163 (sCD163)] Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops) acute-phase response [GO:0006953] GO:0005044; GO:0005576; GO:0005886; GO:0006953 24721 XM_044325496.1 83 20 28 102 117 NA NA NA NA NA NA 24722 XM_044326816.1 1 0 2 14 9 NA NA NA NA NA NA 24723 XM_044328253.1 2032 1330 1169 2211 2248 Q15751 0 Probable E3 ubiquitin-protein ligase HERC1 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 1) (HECT-type E3 ubiquitin transferase HERC1) (p532) (p619) Homo sapiens (Human) autophagy [GO:0006914]; cerebellar Purkinje cell differentiation [GO:0021702]; corpus callosum development [GO:0022038]; negative regulation of autophagy [GO:0010507]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175] GO:0004842; GO:0005085; GO:0005737; GO:0005794; GO:0005829; GO:0006914; GO:0010507; GO:0016020; GO:0021702; GO:0022038; GO:0031175; GO:0050885 24724 XM_044328253.1 2032 1330 1169 2211 2248 Q15751 0 Probable E3 ubiquitin-protein ligase HERC1 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 1) (HECT-type E3 ubiquitin transferase HERC1) (p532) (p619) Homo sapiens (Human) autophagy [GO:0006914]; cerebellar Purkinje cell differentiation [GO:0021702]; corpus callosum development [GO:0022038]; negative regulation of autophagy [GO:0010507]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175] GO:0004842; GO:0005085; GO:0005737; GO:0005794; GO:0005829; GO:0006914; GO:0010507; GO:0016020; GO:0021702; GO:0022038; GO:0031175; GO:0050885 24725 XM_044328253.1 2032 1330 1169 2211 2248 Q15751 3.28e-153 Probable E3 ubiquitin-protein ligase HERC1 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 1) (HECT-type E3 ubiquitin transferase HERC1) (p532) (p619) Homo sapiens (Human) autophagy [GO:0006914]; cerebellar Purkinje cell differentiation [GO:0021702]; corpus callosum development [GO:0022038]; negative regulation of autophagy [GO:0010507]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175] GO:0004842; GO:0005085; GO:0005737; GO:0005794; GO:0005829; GO:0006914; GO:0010507; GO:0016020; GO:0021702; GO:0022038; GO:0031175; GO:0050885 24726 XM_044328253.1 2032 1330 1169 2211 2248 Q15751 1.12e-84 Probable E3 ubiquitin-protein ligase HERC1 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 1) (HECT-type E3 ubiquitin transferase HERC1) (p532) (p619) Homo sapiens (Human) autophagy [GO:0006914]; cerebellar Purkinje cell differentiation [GO:0021702]; corpus callosum development [GO:0022038]; negative regulation of autophagy [GO:0010507]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175] GO:0004842; GO:0005085; GO:0005737; GO:0005794; GO:0005829; GO:0006914; GO:0010507; GO:0016020; GO:0021702; GO:0022038; GO:0031175; GO:0050885 24727 XM_044328253.1 2032 1330 1169 2211 2248 Q15751 2.37e-81 Probable E3 ubiquitin-protein ligase HERC1 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 1) (HECT-type E3 ubiquitin transferase HERC1) (p532) (p619) Homo sapiens (Human) autophagy [GO:0006914]; cerebellar Purkinje cell differentiation [GO:0021702]; corpus callosum development [GO:0022038]; negative regulation of autophagy [GO:0010507]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175] GO:0004842; GO:0005085; GO:0005737; GO:0005794; GO:0005829; GO:0006914; GO:0010507; GO:0016020; GO:0021702; GO:0022038; GO:0031175; GO:0050885 24728 XM_044328049.1 154 97 78 137 101 Q8VBT9 2.52e-80 Tether containing UBX domain for GLUT4 (Alveolar soft part sarcoma chromosomal region candidate gene 1 protein homolog) Mus musculus (Mouse) glucose homeostasis [GO:0042593]; intracellular protein transport [GO:0006886]; positive regulation of protein modification process [GO:0031401]; regulation of glucose import [GO:0046324] GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0006886; GO:0009898; GO:0012505; GO:0012506; GO:0030659; GO:0031401; GO:0033116; GO:0042593; GO:0043231; GO:0046324; GO:0048471 24729 XM_029341068.2 33 50 15 19 86 NA NA NA NA NA NA 24730 XR_006397432.1 36 0 0 37 36 NA NA NA NA NA NA 24731 XM_044315154.1 189 89 131 252 191 NA NA NA NA NA NA 24732 XM_044311137.1 12 20 7 19 25 NA NA NA NA NA NA 24733 XM_044329068.1 251 124 116 261 293 A0JP70 0 WD repeat-containing protein 90 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cilium assembly [GO:0060271] GO:0005737; GO:0005814; GO:0060271 24734 XM_029347830.2 491 423 389 832 659 NA NA NA NA NA NA 24735 XM_044316919.1 2346 1213 1454 1619 3139 Q7ZXG7 7.94e-115 Guanidinoacetate N-methyltransferase A (EC 2.1.1.2) Xenopus laevis (African clawed frog) creatine biosynthetic process [GO:0006601]; methylation [GO:0032259] GO:0006601; GO:0030731; GO:0032259 24736 XM_029335782.2 52 184 51 56 105 P55006 5.28e-74 Retinol dehydrogenase 7 (EC 1.1.1.105) (Retinol dehydrogenase 3) (Retinol dehydrogenase type III) (RODH III) Rattus norvegicus (Rat) retinol metabolic process [GO:0042572]; steroid metabolic process [GO:0008202] GO:0004745; GO:0005783; GO:0008202; GO:0016491; GO:0042572; GO:0043231 24737 XM_029349317.2 36 87 68 202 68 NA NA NA NA NA NA 24738 XM_029337521.2 0 0 0 32 0 O02670 3.65e-81 G protein-activated inward rectifier potassium channel 4 (GIRK-4) (Cardiac inward rectifier) (CIR) (Heart KATP channel) (Inward rectifier K(+) channel Kir3.4) (KATP-1) (Potassium channel, inwardly rectifying subfamily J member 5) Sus scrofa (Pig) membrane repolarization during atrial cardiac muscle cell action potential [GO:0098914]; potassium ion import across plasma membrane [GO:1990573]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ion transmembrane transport [GO:0034765] GO:0005242; GO:0005886; GO:0008076; GO:0015467; GO:0034765; GO:0086089; GO:0086091; GO:0098914; GO:1990573 24739 XM_044324333.1 395 0 0 408 0 G8HTB6 8.41e-49 ZP domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 24740 XR_006395857.1 0 11 0 6 6 NA NA NA NA NA NA 24741 XM_029358568.2 1286 1792 1084 1494 1029 Q5RFA0 0 Negative elongation factor D (NELF-D) (TH1-like protein) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) negative regulation of DNA-templated transcription [GO:0045892] GO:0003723; GO:0005634; GO:0045892 24742 XM_044318090.1 85 1 24 6 68 NA NA NA NA NA NA 24743 XM_044313640.1 7 0 0 4 2 Q6DG03 8.47e-26 Cyclin-D-binding Myb-like transcription factor 1 Danio rerio (Zebrafish) (Brachydanio rerio) cell cycle [GO:0007049]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000976; GO:0000978; GO:0000981; GO:0003700; GO:0005634; GO:0006355; GO:0006357; GO:0007049 24744 XR_006395138.1 0 27 4 6 6 NA NA NA NA NA NA 24745 XM_044309632.1 32 5 17 33 66 P42289 1.79e-32 D(1A) dopamine receptor (Dopamine D1 receptor) Xenopus laevis (African clawed frog) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; vasodilation [GO:0042311] GO:0004930; GO:0004952; GO:0005886; GO:0007189; GO:0042311; GO:0045202 24746 XM_029329708.2 1777 2328 1207 3886 3470 NA NA NA NA NA NA 24747 XR_006395017.1 10 0 0 7 40 NA NA NA NA NA NA 24748 XM_044317031.1 407 679 408 688 631 Q32L63 1.92e-84 Vacuolar protein sorting-associated protein VTA1 homolog Bos taurus (Bovine) late endosome to vacuole transport via multivesicular body sorting pathway [GO:0032511]; protein transport [GO:0015031] GO:0010008; GO:0015031; GO:0032511 24749 XR_006395239.1 403 1554 83 137 59 NA NA NA NA NA NA 24750 XM_044319241.1 9 21 44 49 24 NA NA NA NA NA NA 24751 XM_029354045.2 11189 16740 4945 6843 1313 Q8BHP7 1.97e-43 Olfactomedin-like protein 2A (Photomedin-1) Mus musculus (Mouse) extracellular matrix organization [GO:0030198]; signal transduction [GO:0007165] GO:0005615; GO:0007165; GO:0030198; GO:0031012; GO:0042802; GO:0050840 24752 XM_044320380.1 1 423 144 1021 236 Q14517 0 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 24753 XM_044320380.1 1 423 144 1021 236 Q14517 6.58e-55 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 24754 XM_044320380.1 1 423 144 1021 236 Q14517 1.08e-34 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 24755 XM_044322931.1 336 266 144 185 512 NA NA NA NA NA NA 24756 XM_029340093.2 0 70 0 12 0 Q0GGW5 3.92e-149 Serine/threonine-protein kinase STK11 (EC 2.7.11.1) (Liver kinase B1 homolog) (LKB1) Gallus gallus (Chicken) activation of protein kinase activity [GO:0032147]; cell cycle [GO:0007049]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to starvation [GO:0009267]; establishment of cell polarity [GO:0030010]; glucose homeostasis [GO:0042593]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell growth [GO:0030308]; positive regulation of vesicle transport along microtubule [GO:1901610]; protein autophosphorylation [GO:0046777]; protein dephosphorylation [GO:0006470]; protein phosphorylation [GO:0006468]; regulation of cell growth [GO:0001558]; regulation of Wnt signaling pathway [GO:0030111]; response to ionizing radiation [GO:0010212]; response to xenobiotic stimulus [GO:0009410]; signal transduction [GO:0007165]; vasculature development [GO:0001944] GO:0000287; GO:0001558; GO:0001944; GO:0002039; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0006468; GO:0006470; GO:0006974; GO:0007049; GO:0007165; GO:0009267; GO:0009410; GO:0010212; GO:0016020; GO:0019901; GO:0030010; GO:0030111; GO:0030295; GO:0030308; GO:0032147; GO:0042593; GO:0046777; GO:0072332; GO:0090090; GO:0106310; GO:1901610 24757 XM_044308237.1 70 28 34 2 43 NA NA NA NA NA NA 24758 XM_044309557.1 250 856 318 302 1372 NA NA NA NA NA NA 24759 XM_044319555.1 120 67 69 122 129 NA NA NA NA NA NA 24760 XM_029336697.2 214 45 0 143 217 NA NA NA NA NA NA 24761 XM_029333980.2 101 18 52 19 0 NA NA NA NA NA NA 24762 XM_044321238.1 29 0 10 12 19 NA NA NA NA NA NA 24763 XM_044308889.1 5 2 11 81 28 NA NA NA NA NA NA 24764 XM_029338145.2 34 26 19 33 78 Q8UW76 3.46e-40 T-box transcription factor TBX20 (T-box protein 20) (cTbx20) Gallus gallus (Chicken) aortic valve morphogenesis [GO:0003180]; atrial septum morphogenesis [GO:0060413]; atrioventricular canal development [GO:0036302]; blood circulation [GO:0008015]; branching involved in blood vessel morphogenesis [GO:0001569]; cardiac chamber formation [GO:0003207]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac right ventricle morphogenesis [GO:0003215]; cell fate specification [GO:0001708]; cell migration involved in heart development [GO:0060973]; cell proliferation involved in heart valve development [GO:2000793]; dorsal/ventral pattern formation [GO:0009953]; embryonic heart tube elongation [GO:0036306]; endocardial cushion formation [GO:0003272]; foramen ovale closure [GO:0035922]; heart looping [GO:0001947]; mesenchymal cell development [GO:0014031]; motor neuron migration [GO:0097475]; muscle contraction [GO:0006936]; negative regulation of gene expression [GO:0010629]; negative regulation of SMAD protein complex assembly [GO:0010991]; negative regulation of transcription by RNA polymerase II [GO:0000122]; outflow tract septum morphogenesis [GO:0003148]; pericardium morphogenesis [GO:0003344]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell migration [GO:0030335]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of gene expression [GO:0010628]; pulmonary valve formation [GO:0003193]; pulmonary vein morphogenesis [GO:0060577]; regulation of transcription by RNA polymerase II [GO:0006357]; tricuspid valve development [GO:0003175]; vasculogenesis [GO:0001570]; visceral motor neuron differentiation [GO:0021524] GO:0000122; GO:0000978; GO:0000981; GO:0001228; GO:0001569; GO:0001570; GO:0001708; GO:0001947; GO:0003148; GO:0003175; GO:0003180; GO:0003193; GO:0003207; GO:0003215; GO:0003272; GO:0003344; GO:0005634; GO:0005737; GO:0006357; GO:0006936; GO:0008015; GO:0009953; GO:0010628; GO:0010629; GO:0010718; GO:0010991; GO:0014031; GO:0021524; GO:0030335; GO:0030513; GO:0035922; GO:0036302; GO:0036306; GO:0055008; GO:0060045; GO:0060413; GO:0060577; GO:0060973; GO:0061629; GO:0097475; GO:2000793 24765 XM_044316609.1 544 380 292 859 934 Q6TMK4 7.31e-90 Peroxinectin A (EC 1.11.1.7) Dictyostelium discoideum (Social amoeba) defense response to bacterium [GO:0042742]; hydrogen peroxide catabolic process [GO:0042744]; immune response [GO:0006955]; response to oxidative stress [GO:0006979] GO:0004447; GO:0004601; GO:0005576; GO:0005783; GO:0006955; GO:0006979; GO:0020037; GO:0036393; GO:0042742; GO:0042744; GO:0140825 24766 XM_044329146.1 0 16 0 0 31 NA NA NA NA NA NA 24767 XM_029332042.2 17 0 4 0 10 NA NA NA NA NA NA 24768 XM_029350685.2 18216 12712 12088 16522 11798 Q3ZBG9 4.93e-87 Phospholipid scramblase 2 (PL scramblase 2) (Ca(2+)-dependent phospholipid scramblase 2) Bos taurus (Bovine) plasma membrane phospholipid scrambling [GO:0017121] GO:0005886; GO:0017121; GO:0017128; GO:0046872 24769 XM_029323520.2 10 25 25 16 32 NA NA NA NA NA NA 24770 XM_029344545.2 261 153 106 337 360 Q9DER7 0 Tolloid-like protein 1 (EC 3.4.24.-) (Chicken tolloid-like protein 1) (Metalloprotease colloid) Gallus gallus (Chicken) cell differentiation [GO:0030154]; dorsal/ventral pattern formation [GO:0009953]; protein processing [GO:0016485] GO:0004222; GO:0005509; GO:0005615; GO:0008270; GO:0009953; GO:0016485; GO:0030154 24771 XM_044317473.1 67 14 42 61 45 NA NA NA NA NA NA 24772 XM_029337910.2 552 388 364 533 667 Q9UNX4 0 WD repeat-containing protein 3 Homo sapiens (Human) maturation of SSU-rRNA [GO:0030490] GO:0003723; GO:0005654; GO:0005730; GO:0030490; GO:0030515; GO:0031965; GO:0032040; GO:0034388 24773 XM_044327302.1 39 126 18 42 71 NA NA NA NA NA NA 24774 XR_006391561.1 12 14 0 4 21 NA NA NA NA NA NA 24775 XM_044318701.1 40 0 17 0 1 NA NA NA NA NA NA 24776 XR_003823811.2 1 2 7 1 65 NA NA NA NA NA NA 24777 XM_044319595.1 4 0 1 2 10 NA NA NA NA NA NA 24778 XM_029340170.2 17860 15556 7717 11763 7875 Q942L2 4.45e-107 Protein disulfide isomerase-like 2-2 (OsPDIL2-2) (EC 5.3.4.1) (Protein disulfide isomerase-like 4-2) (OsPDIL4-2) Oryza sativa subsp. japonica (Rice) protein folding [GO:0006457] GO:0003756; GO:0005576; GO:0005783; GO:0006457 24779 XM_044320896.1 319 482 504 555 582 Q5JL96 2.03e-28 Probable E3 ubiquitin-protein ligase RZFP34 (EC 2.3.2.27) (OsRFP1) (RING zinc-finger protein 34) (OsRZFP34) Oryza sativa subsp. japonica (Rice) protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0005634; GO:0006511; GO:0008270; GO:0016567; GO:0061630 24780 XM_044321701.1 0 0 0 108 0 B6CHA3 0 E3 ubiquitin-protein ligase UHRF1 (EC 2.3.2.27) (Nuclear zinc finger protein Np95) (XNp95) (RING-type E3 ubiquitin transferase UHRF1) (Ubiquitin-like PHD and RING finger domain-containing protein 1) (Ubiquitin-like-containing PHD and RING finger domains protein 1) Xenopus laevis (African clawed frog) cell cycle [GO:0007049]; chromatin organization [GO:0006325]; histone ubiquitination [GO:0016574]; maintenance of DNA methylation [GO:0010216]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein autoubiquitination [GO:0051865]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000122; GO:0000785; GO:0000791; GO:0000792; GO:0004842; GO:0005634; GO:0005657; GO:0006325; GO:0006511; GO:0007049; GO:0008270; GO:0010216; GO:0016574; GO:0035064; GO:0042393; GO:0044729; GO:0051865 24781 XM_044309907.1 1075 4 315 1126 1162 NA NA NA NA NA NA 24782 XM_029340708.2 557 329 425 563 491 Q9NQX0 8.32e-91 Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.361) (PR domain zinc finger protein 6) (PR domain-containing protein 6) Homo sapiens (Human) chromatin organization [GO:0006325]; histone methylation [GO:0016571]; negative regulation of smooth muscle cell differentiation [GO:0051151]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of gene expression [GO:0010468] GO:0000122; GO:0005634; GO:0006325; GO:0010468; GO:0016571; GO:0022008; GO:0042802; GO:0046872; GO:0051151; GO:0140944 24783 XR_006392810.1 1 6 14 9 27 NA NA NA NA NA NA 24784 XM_029353732.2 0 19 0 57 0 P35406 4.32e-37 D(1) dopamine receptor (Dopamine D1 receptor) Carassius auratus (Goldfish) regulation of biological quality [GO:0065008] GO:0004930; GO:0005886; GO:0065008 24785 XM_044327066.1 13790 13632 10501 22381 17512 Q8BTM8 0 Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin) Mus musculus (Mouse) actin crosslink formation [GO:0051764]; actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; angiogenesis [GO:0001525]; blood coagulation, intrinsic pathway [GO:0007597]; blood vessel remodeling [GO:0001974]; cell-cell junction organization [GO:0045216]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; early endosome to late endosome transport [GO:0045022]; epithelial to mesenchymal transition [GO:0001837]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; heart morphogenesis [GO:0003007]; megakaryocyte development [GO:0035855]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of axon regeneration [GO:0048680]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of platelet activation [GO:0010572]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; release of sequestered calcium ion into cytosol [GO:0051209]; semaphorin-plexin signaling pathway [GO:0071526]; synapse organization [GO:0050808]; tubulin deacetylation [GO:0090042]; wound healing, spreading of cells [GO:0044319] GO:0001525; GO:0001664; GO:0001837; GO:0001974; GO:0003007; GO:0003779; GO:0005080; GO:0005634; GO:0005730; GO:0005737; GO:0005802; GO:0005829; GO:0005884; GO:0005886; GO:0005903; GO:0005911; GO:0005938; GO:0007195; GO:0007597; GO:0010572; GO:0010977; GO:0015459; GO:0015629; GO:0016479; GO:0019900; GO:0021943; GO:0030018; GO:0030036; GO:0030334; GO:0030426; GO:0030863; GO:0031267; GO:0031523; GO:0031532; GO:0031852; GO:0032231; GO:0032233; GO:0032432; GO:0034394; GO:0034988; GO:0035855; GO:0042177; GO:0042307; GO:0042789; GO:0042803; GO:0043025; GO:0043066; GO:0043113; GO:0043123; GO:0043198; GO:0043204; GO:0043433; GO:0044295; GO:0044319; GO:0044325; GO:0044877; GO:0045022; GO:0045184; GO:0045216; GO:0046332; GO:0048471; GO:0048680; GO:0050808; GO:0050821; GO:0051015; GO:0051020; GO:0051209; GO:0051220; GO:0051764; GO:0060271; GO:0071526; GO:0072659; GO:0090042; GO:0090307; GO:0097368; GO:0097440; GO:0098794; GO:0098978; GO:0140297; GO:1900026; GO:1901381; GO:1902396; GO:1905000; GO:1905031; GO:1990779; GO:2000179; GO:2001046; GO:2001224 24786 XM_044327066.1 13790 13632 10501 22381 17512 Q8BTM8 0 Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin) Mus musculus (Mouse) actin crosslink formation [GO:0051764]; actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; angiogenesis [GO:0001525]; blood coagulation, intrinsic pathway [GO:0007597]; blood vessel remodeling [GO:0001974]; cell-cell junction organization [GO:0045216]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; early endosome to late endosome transport [GO:0045022]; epithelial to mesenchymal transition [GO:0001837]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; heart morphogenesis [GO:0003007]; megakaryocyte development [GO:0035855]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of axon regeneration [GO:0048680]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of platelet activation [GO:0010572]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; release of sequestered calcium ion into cytosol [GO:0051209]; semaphorin-plexin signaling pathway [GO:0071526]; synapse organization [GO:0050808]; tubulin deacetylation [GO:0090042]; wound healing, spreading of cells [GO:0044319] GO:0001525; GO:0001664; GO:0001837; GO:0001974; GO:0003007; GO:0003779; GO:0005080; GO:0005634; GO:0005730; GO:0005737; GO:0005802; GO:0005829; GO:0005884; GO:0005886; GO:0005903; GO:0005911; GO:0005938; GO:0007195; GO:0007597; GO:0010572; GO:0010977; GO:0015459; GO:0015629; GO:0016479; GO:0019900; GO:0021943; GO:0030018; GO:0030036; GO:0030334; GO:0030426; GO:0030863; GO:0031267; GO:0031523; GO:0031532; GO:0031852; GO:0032231; GO:0032233; GO:0032432; GO:0034394; GO:0034988; GO:0035855; GO:0042177; GO:0042307; GO:0042789; GO:0042803; GO:0043025; GO:0043066; GO:0043113; GO:0043123; GO:0043198; GO:0043204; GO:0043433; GO:0044295; GO:0044319; GO:0044325; GO:0044877; GO:0045022; GO:0045184; GO:0045216; GO:0046332; GO:0048471; GO:0048680; GO:0050808; GO:0050821; GO:0051015; GO:0051020; GO:0051209; GO:0051220; GO:0051764; GO:0060271; GO:0071526; GO:0072659; GO:0090042; GO:0090307; GO:0097368; GO:0097440; GO:0098794; GO:0098978; GO:0140297; GO:1900026; GO:1901381; GO:1902396; GO:1905000; GO:1905031; GO:1990779; GO:2000179; GO:2001046; GO:2001224 24787 XM_044327066.1 13790 13632 10501 22381 17512 Q8BTM8 6.22e-62 Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin) Mus musculus (Mouse) actin crosslink formation [GO:0051764]; actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; angiogenesis [GO:0001525]; blood coagulation, intrinsic pathway [GO:0007597]; blood vessel remodeling [GO:0001974]; cell-cell junction organization [GO:0045216]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; early endosome to late endosome transport [GO:0045022]; epithelial to mesenchymal transition [GO:0001837]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; heart morphogenesis [GO:0003007]; megakaryocyte development [GO:0035855]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of axon regeneration [GO:0048680]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of platelet activation [GO:0010572]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; release of sequestered calcium ion into cytosol [GO:0051209]; semaphorin-plexin signaling pathway [GO:0071526]; synapse organization [GO:0050808]; tubulin deacetylation [GO:0090042]; wound healing, spreading of cells [GO:0044319] GO:0001525; GO:0001664; GO:0001837; GO:0001974; GO:0003007; GO:0003779; GO:0005080; GO:0005634; GO:0005730; GO:0005737; GO:0005802; GO:0005829; GO:0005884; GO:0005886; GO:0005903; GO:0005911; GO:0005938; GO:0007195; GO:0007597; GO:0010572; GO:0010977; GO:0015459; GO:0015629; GO:0016479; GO:0019900; GO:0021943; GO:0030018; GO:0030036; GO:0030334; GO:0030426; GO:0030863; GO:0031267; GO:0031523; GO:0031532; GO:0031852; GO:0032231; GO:0032233; GO:0032432; GO:0034394; GO:0034988; GO:0035855; GO:0042177; GO:0042307; GO:0042789; GO:0042803; GO:0043025; GO:0043066; GO:0043113; GO:0043123; GO:0043198; GO:0043204; GO:0043433; GO:0044295; GO:0044319; GO:0044325; GO:0044877; GO:0045022; GO:0045184; GO:0045216; GO:0046332; GO:0048471; GO:0048680; GO:0050808; GO:0050821; GO:0051015; GO:0051020; GO:0051209; GO:0051220; GO:0051764; GO:0060271; GO:0071526; GO:0072659; GO:0090042; GO:0090307; GO:0097368; GO:0097440; GO:0098794; GO:0098978; GO:0140297; GO:1900026; GO:1901381; GO:1902396; GO:1905000; GO:1905031; GO:1990779; GO:2000179; GO:2001046; GO:2001224 24788 XM_044327066.1 13790 13632 10501 22381 17512 Q8BTM8 8.48e-30 Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin) Mus musculus (Mouse) actin crosslink formation [GO:0051764]; actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; angiogenesis [GO:0001525]; blood coagulation, intrinsic pathway [GO:0007597]; blood vessel remodeling [GO:0001974]; cell-cell junction organization [GO:0045216]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; early endosome to late endosome transport [GO:0045022]; epithelial to mesenchymal transition [GO:0001837]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; heart morphogenesis [GO:0003007]; megakaryocyte development [GO:0035855]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of axon regeneration [GO:0048680]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of platelet activation [GO:0010572]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; release of sequestered calcium ion into cytosol [GO:0051209]; semaphorin-plexin signaling pathway [GO:0071526]; synapse organization [GO:0050808]; tubulin deacetylation [GO:0090042]; wound healing, spreading of cells [GO:0044319] GO:0001525; GO:0001664; GO:0001837; GO:0001974; GO:0003007; GO:0003779; GO:0005080; GO:0005634; GO:0005730; GO:0005737; GO:0005802; GO:0005829; GO:0005884; GO:0005886; GO:0005903; GO:0005911; GO:0005938; GO:0007195; GO:0007597; GO:0010572; GO:0010977; GO:0015459; GO:0015629; GO:0016479; GO:0019900; GO:0021943; GO:0030018; GO:0030036; GO:0030334; GO:0030426; GO:0030863; GO:0031267; GO:0031523; GO:0031532; GO:0031852; GO:0032231; GO:0032233; GO:0032432; GO:0034394; GO:0034988; GO:0035855; GO:0042177; GO:0042307; GO:0042789; GO:0042803; GO:0043025; GO:0043066; GO:0043113; GO:0043123; GO:0043198; GO:0043204; GO:0043433; GO:0044295; GO:0044319; GO:0044325; GO:0044877; GO:0045022; GO:0045184; GO:0045216; GO:0046332; GO:0048471; GO:0048680; GO:0050808; GO:0050821; GO:0051015; GO:0051020; GO:0051209; GO:0051220; GO:0051764; GO:0060271; GO:0071526; GO:0072659; GO:0090042; GO:0090307; GO:0097368; GO:0097440; GO:0098794; GO:0098978; GO:0140297; GO:1900026; GO:1901381; GO:1902396; GO:1905000; GO:1905031; GO:1990779; GO:2000179; GO:2001046; GO:2001224 24789 XM_044324480.1 259 266 120 263 242 Q80XJ3 1.31e-71 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 24790 XM_044324480.1 259 266 120 263 242 Q80XJ3 2.15e-70 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 24791 XM_044324480.1 259 266 120 263 242 Q80XJ3 1.44e-69 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 24792 XM_044324480.1 259 266 120 263 242 Q80XJ3 8.03e-69 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 24793 XM_044324480.1 259 266 120 263 242 Q80XJ3 3.39e-67 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 24794 XM_044324480.1 259 266 120 263 242 Q80XJ3 7.95e-55 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 24795 XM_044324480.1 259 266 120 263 242 Q80XJ3 1.05e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 24796 XM_044312164.1 2 0 3 7 8 NA NA NA NA NA NA 24797 XM_044308853.1 302 120 172 170 381 Q07496 3.03e-84 Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) (cEK8) Gallus gallus (Chicken) axon guidance [GO:0007411]; cell adhesion [GO:0007155]; fasciculation of sensory neuron axon [GO:0097155]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of kinase activity [GO:0033674]; positive regulation of Rho guanyl-nucleotide exchange factor activity [GO:2001108]; protein autophosphorylation [GO:0046777]; regulation of GTPase activity [GO:0043087]; segmentation [GO:0035282]; somitogenesis [GO:0001756]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0001756; GO:0004672; GO:0004714; GO:0005004; GO:0005005; GO:0005524; GO:0005737; GO:0005886; GO:0007155; GO:0007169; GO:0007411; GO:0018108; GO:0031901; GO:0033674; GO:0035282; GO:0043005; GO:0043087; GO:0043197; GO:0043235; GO:0046777; GO:0097155; GO:0097161; GO:2001108 24798 XM_044321519.1 0 0 0 12 0 NA NA NA NA NA NA 24799 XM_029341811.2 458 109 477 572 541 A2AJ88 0 Patatin-like phospholipase domain-containing protein 7 (EC 3.1.1.-) (EC 3.1.1.5) (Neuropathy target esterase-related esterase) (NRE) (NTE-related esterase) Mus musculus (Mouse) phosphatidylcholine catabolic process [GO:0034638] GO:0004622; GO:0005783; GO:0005789; GO:0005811; GO:0034638; GO:0102545 24800 XM_029358429.2 0 0 0 20 0 NA NA NA NA NA NA 24801 XR_006392988.1 41 2 25 5 151 NA NA NA NA NA NA 24802 XM_044316671.1 198 94 80 213 0 O43301 0 Heat shock 70 kDa protein 12A Homo sapiens (Human) NA GO:0005524; GO:0005634; GO:0005737; GO:0070062 24803 XM_029325587.2 105 209 254 105 106 Q5F2L1 4.22e-123 Alpha-(1,3)-fucosyltransferase 10 (EC 2.4.1.-) (Fucosyltransferase X) (Fuc-TX) (FucT-X) (Galactoside 3-L-fucosyltransferase 10) (Fucosyltransferase 10) Rattus norvegicus (Rat) cerebral cortex radially oriented cell migration [GO:0021799]; fucosylation [GO:0036065]; N-glycan fucosylation [GO:0036071]; neuroblast migration [GO:0097402]; neuronal stem cell division [GO:0036445]; neuronal stem cell population maintenance [GO:0097150]; oligosaccharide biosynthetic process [GO:0009312]; protein glycosylation [GO:0006486] GO:0000139; GO:0005789; GO:0006486; GO:0008417; GO:0009312; GO:0021799; GO:0036065; GO:0036071; GO:0036445; GO:0046920; GO:0097150; GO:0097402 24804 XR_006394697.1 6438 4402 4219 8778 6459 Q9NZM1 0 Myoferlin (Fer-1-like protein 3) Homo sapiens (Human) blood circulation [GO:0008015]; membrane fusion [GO:0061025]; muscle contraction [GO:0006936]; plasma membrane organization [GO:0007009]; plasma membrane repair [GO:0001778]; T-tubule organization [GO:0033292] GO:0001778; GO:0005543; GO:0005635; GO:0005886; GO:0005901; GO:0006936; GO:0007009; GO:0008015; GO:0030659; GO:0031410; GO:0031965; GO:0033292; GO:0043231; GO:0046872; GO:0061025; GO:0070062 24805 XR_006394697.1 6438 4402 4219 8778 6459 Q9NZM1 0 Myoferlin (Fer-1-like protein 3) Homo sapiens (Human) blood circulation [GO:0008015]; membrane fusion [GO:0061025]; muscle contraction [GO:0006936]; plasma membrane organization [GO:0007009]; plasma membrane repair [GO:0001778]; T-tubule organization [GO:0033292] GO:0001778; GO:0005543; GO:0005635; GO:0005886; GO:0005901; GO:0006936; GO:0007009; GO:0008015; GO:0030659; GO:0031410; GO:0031965; GO:0033292; GO:0043231; GO:0046872; GO:0061025; GO:0070062 24806 XM_029349914.2 717 740 453 706 928 Q5F489 1.38e-34 Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) Gallus gallus (Chicken) NA GO:0005669; GO:0046872; GO:0046982 24807 XM_029356568.2 8568 6914 4466 7531 7476 A6QLP7 1.98e-47 Translocon-associated protein subunit alpha (TRAP-alpha) (Signal sequence receptor subunit alpha) (SSR-alpha) Bos taurus (Bovine) NA GO:0005783; GO:0005789 24808 XM_029341042.2 56 151 75 194 193 Q3V0J4 2.2e-32 Ankyrin repeat domain-containing protein 53 Mus musculus (Mouse) cell division [GO:0051301]; mitotic metaphase plate congression [GO:0007080]; positive regulation of microtubule polymerization [GO:0031116]; regulation of mitotic cytokinesis [GO:1902412]; regulation of mitotic spindle organization [GO:0060236] GO:0000922; GO:0005737; GO:0005819; GO:0007080; GO:0031116; GO:0051301; GO:0060236; GO:1902412 24809 XM_029341979.2 97 632 40 876 51 Q9CYL5 5.29e-33 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Mus musculus (Mouse) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070374 24810 XM_029341979.2 97 632 40 876 51 Q9CYL5 1.58e-23 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Mus musculus (Mouse) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070374 24811 XM_029341979.2 97 632 40 876 51 Q9CYL5 1.72e-21 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Mus musculus (Mouse) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070374 24812 XM_029332174.2 3309 1930 2746 1831 1686 Q58CP9 2.65e-110 Stromal interaction molecule 1 Bos taurus (Bovine) activation of store-operated calcium channel activity [GO:0032237]; cellular calcium ion homeostasis [GO:0006874]; detection of calcium ion [GO:0005513]; enamel mineralization [GO:0070166]; positive regulation of adenylate cyclase activity [GO:0045762]; regulation of calcium ion transport [GO:0051924]; regulation of store-operated calcium entry [GO:2001256]; store-operated calcium entry [GO:0002115] GO:0002115; GO:0005246; GO:0005509; GO:0005513; GO:0005783; GO:0005789; GO:0005874; GO:0005886; GO:0006874; GO:0032237; GO:0033017; GO:0044853; GO:0045762; GO:0051010; GO:0051924; GO:0070166; GO:2001256 24813 XM_044307614.1 455 183 10 250 83 NA NA NA NA NA NA 24814 XM_044322270.1 190 336 110 451 32 NA NA NA NA NA NA 24815 XM_029340665.2 76 136 159 658 335 Q6P0C6 4.05e-48 LHFPL tetraspan subfamily member 2a protein Danio rerio (Zebrafish) (Brachydanio rerio) development of primary female sexual characteristics [GO:0046545]; development of primary male sexual characteristics [GO:0046546]; positive regulation of fertilization [GO:1905516]; single fertilization [GO:0007338] GO:0007338; GO:0016020; GO:0046545; GO:0046546; GO:1905516 24816 XM_044314562.1 286 165 123 167 111 NA NA NA NA NA NA 24817 XM_044314101.1 69 0 0 68 137 NA NA NA NA NA NA 24818 XM_044317188.1 7009 7437 5682 7601 8318 P85515 0 Alpha-centractin (Centractin) Rattus norvegicus (Rat) spermatogenesis [GO:0007283] GO:0002177; GO:0005524; GO:0005813; GO:0005814; GO:0005938; GO:0007283; GO:0030137 24819 XM_044323067.1 77 47 168 48 40 NA NA NA NA NA NA 24820 XM_029341277.2 322 242 261 592 478 NA NA NA NA NA NA 24821 XM_044311732.1 31 15 5 21 36 NA NA NA NA NA NA 24822 XM_044318180.1 99 40 58 114 28 Q2TBT5 3.47e-104 Ribonuclease H2 subunit A (RNase H2 subunit A) (EC 3.1.26.4) (Ribonuclease HI large subunit) (RNase HI large subunit) (Ribonuclease HI subunit A) Bos taurus (Bovine) DNA replication, removal of RNA primer [GO:0043137]; mismatch repair [GO:0006298]; RNA catabolic process [GO:0006401] GO:0003723; GO:0004523; GO:0005654; GO:0005829; GO:0006298; GO:0006401; GO:0032299; GO:0043137; GO:0046872 24823 XM_029339034.2 0 0 0 16 12 NA NA NA NA NA NA 24824 XM_029338187.2 107 12 13 14 30 NA NA NA NA NA NA 24825 XM_029348643.2 331 305 178 433 391 P56213 1.18e-57 FAD-linked sulfhydryl oxidase ALR (EC 1.8.3.2) (Augmenter of liver regeneration) Mus musculus (Mouse) cellular response to actinomycin D [GO:0072717]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to toxic substance [GO:0097237]; cellular response to tumor necrosis factor [GO:0071356]; liver development [GO:0001889]; liver regeneration [GO:0097421]; negative regulation of apoptotic process [GO:0043066]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of oxidative stress-induced neuron death [GO:1903204]; positive regulation of DNA biosynthetic process [GO:2000573] GO:0001889; GO:0005615; GO:0005739; GO:0005758; GO:0005829; GO:0008083; GO:0015035; GO:0016971; GO:0043066; GO:0045953; GO:0050660; GO:0071222; GO:0071356; GO:0072717; GO:0097237; GO:0097421; GO:1903204; GO:2000573 24826 XM_029339935.2 0 181 0 95 0 A0JM56 0 Leucine-rich repeat-containing protein 9 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737 24827 XM_044316935.1 8 15 13 4 0 NA NA NA NA NA NA 24828 XM_044307818.1 15 0 4 5 70 NA NA NA NA NA NA 24829 XM_044326774.1 2 19 11 6 10 NA NA NA NA NA NA 24830 XR_006393884.1 9 0 25 2 37 NA NA NA NA NA NA 24831 XM_029328548.2 12 0 0 272 265 Q3TLD5 2.88e-29 Unconventional prefoldin RPB5 interactor (Protein NNX3) (Protein phosphatase 1 regulatory subunit 19) (RNA polymerase II subunit 5-mediating protein) (RPB5-mediating protein) Mus musculus (Mouse) cellular response to growth factor stimulus [GO:0071363]; cellular response to steroid hormone stimulus [GO:0071383]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of phosphatase activity [GO:0010923]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of cell growth [GO:0001558]; regulation of transcription by RNA polymerase II [GO:0006357]; response to virus [GO:0009615] GO:0000122; GO:0000993; GO:0001558; GO:0003682; GO:0003714; GO:0004864; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005829; GO:0006357; GO:0009615; GO:0010923; GO:0019212; GO:0030425; GO:0051219; GO:0071363; GO:0071383; GO:1990062; GO:2001243 24832 XM_044320517.1 57 5 24 53 0 NA NA NA NA NA NA 24833 XM_029330984.2 414 352 68 68 154 Q9R022 5.38e-29 DnaJ homolog subfamily C member 12 (J domain-containing protein 1) Mus musculus (Mouse) NA GO:0005737 24834 XM_029342133.2 0 0 0 8 0 Q5SVQ0 1.1e-159 Histone acetyltransferase KAT7 (EC 2.3.1.48) (Histone acetyltransferase binding to ORC1) (Lysine acetyltransferase 7) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (MYST-2) Mus musculus (Mouse) DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication-dependent chromatin disassembly [GO:0140889]; histone H4-K12 acetylation [GO:0043983]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; histone modification [GO:0016570]; internal peptidyl-lysine acetylation [GO:0018393]; natural killer cell differentiation [GO:0001779]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of DNA replication [GO:0045740]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell cycle [GO:0051726]; regulation of cell growth [GO:0001558]; regulation of DNA biosynthetic process [GO:2000278]; regulation of DNA replication [GO:0006275]; regulation of DNA-templated DNA replication initiation [GO:0030174]; regulation of DNA-templated transcription [GO:0006355]; regulation of nucleotide-excision repair [GO:2000819]; response to actinomycin D [GO:0072716]; response to anisomycin [GO:0072739]; response to dithiothreitol [GO:0072720]; response to hydroxyurea [GO:0072710]; response to sorbitol [GO:0072708]; stress-activated protein kinase signaling cascade [GO:0031098]; T cell differentiation [GO:0030217]; transcription initiation-coupled chromatin remodeling [GO:0045815] GO:0000123; GO:0000775; GO:0001558; GO:0001779; GO:0003688; GO:0003712; GO:0004402; GO:0005634; GO:0005654; GO:0005694; GO:0005829; GO:0006260; GO:0006275; GO:0006281; GO:0006355; GO:0008270; GO:0010485; GO:0016570; GO:0018393; GO:0030174; GO:0030217; GO:0031098; GO:0032786; GO:0036408; GO:0036409; GO:0042393; GO:0043981; GO:0043982; GO:0043983; GO:0043994; GO:0043995; GO:0043996; GO:0043997; GO:0044016; GO:0045648; GO:0045740; GO:0045815; GO:0045892; GO:0045944; GO:0051726; GO:0072708; GO:0072710; GO:0072716; GO:0072720; GO:0072739; GO:0090734; GO:0140889; GO:1900182; GO:1902035; GO:2000278; GO:2000819 24835 XM_029331895.2 857 528 589 768 1136 O95628 1.98e-128 CCR4-NOT transcription complex subunit 4 (EC 2.3.2.27) (CCR4-associated factor 4) (E3 ubiquitin-protein ligase CNOT4) (Potential transcriptional repressor NOT4Hp) (RING-type E3 ubiquitin transferase CNOT4) Homo sapiens (Human) nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; protein autoubiquitination [GO:0051865]; protein ubiquitination [GO:0016567]; regulation of megakaryocyte differentiation [GO:0045652]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000289; GO:0003723; GO:0004842; GO:0005634; GO:0005829; GO:0006511; GO:0016567; GO:0030014; GO:0045652; GO:0046872; GO:0051865 24836 XM_044307401.1 79 5 83 5 167 Q6AZB8 8.77e-62 Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0004518; GO:0005634; GO:0005737; GO:0046872 24837 XM_029332295.2 24 0 0 62 15 Q9N294 1.35e-31 Beta-1,3-galactosyltransferase 5 (Beta-1,3-GalTase 5) (Beta3Gal-T5) (Beta3GalT5) (b3Gal-T5) (EC 2.4.1.-) (Beta-3-Gx-T5) (UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 5) (UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 5) Pan paniscus (Pygmy chimpanzee) (Bonobo) lipid metabolic process [GO:0006629]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0006629; GO:0016758 24838 XR_006392821.1 1098 782 586 814 1162 NA NA NA NA NA NA 24839 XM_044326079.1 0 6 0 0 0 NA NA NA NA NA NA 24840 XM_029323887.2 109 43 41 72 95 Q8I7P9 1.97e-24 Retrovirus-related Pol polyprotein from transposon opus [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508]; transposition, DNA-mediated [GO:0006313] GO:0003676; GO:0003887; GO:0003964; GO:0004519; GO:0005634; GO:0006313; GO:0006508; GO:0008233; GO:0015074; GO:0042575 24841 XM_029333963.2 18 3 30 19 56 NA NA NA NA NA NA 24842 XM_044313103.1 3 52 4 3 31 NA NA NA NA NA NA 24843 XM_029333379.2 123 194 83 115 204 Q90722 3.5e-22 Fibroblast growth factor 8 (FGF-8) (Heparin-binding growth factor 8) (HBGF-8) Gallus gallus (Chicken) cartilage development [GO:0051216]; cell differentiation [GO:0030154]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; epithelial-mesenchymal cell signaling [GO:0060684]; limb bud formation [GO:0060174]; limb development [GO:0060173]; positive regulation of cell division [GO:0051781]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of gene expression [GO:0010468]; response to fibroblast growth factor [GO:0071774] GO:0005576; GO:0008083; GO:0009880; GO:0010468; GO:0010628; GO:0030154; GO:0030177; GO:0030326; GO:0042733; GO:0045893; GO:0045944; GO:0051216; GO:0051781; GO:0060173; GO:0060174; GO:0060684; GO:0071774 24844 XM_044315064.1 63 7 33 610 115 Q969X5 3.63e-132 Endoplasmic reticulum-Golgi intermediate compartment protein 1 (ER-Golgi intermediate compartment 32 kDa protein) (ERGIC-32) Homo sapiens (Human) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] GO:0000139; GO:0005654; GO:0005783; GO:0005789; GO:0005793; GO:0006888; GO:0006890; GO:0016020; GO:0030134; GO:0033116; GO:0043231 24845 XR_006398189.1 36 13 11 12 84 NA NA NA NA NA NA 24846 XM_029346483.2 1169 1358 1145 930 820 Q504M2 7.7e-84 NA NA NA NA 24847 XM_029356260.2 2598 2657 1263 1678 1042 Q9DCT6 7.94e-25 Chromatin complexes subunit BAP18 (BPTF-associated protein of 18 kDa) Mus musculus (Mouse) chromatin organization [GO:0006325] GO:0003677; GO:0005654; GO:0005829; GO:0006325; GO:0016589; GO:0042802; GO:0071339 24848 XM_044310252.1 6 1 14 0 0 NA NA NA NA NA NA 24849 XM_044315588.1 0 0 7 14 0 NA NA NA NA NA NA 24850 XR_006397051.1 0 9 13 0 9 NA NA NA NA NA NA 24851 XM_044323106.1 25 789 2 495 0 NA NA NA NA NA NA 24852 XM_044328045.1 66 42 68 33 81 P42125 1.86e-57 Enoyl-CoA delta isomerase 1, mitochondrial (EC 5.3.3.8) (3,2-trans-enoyl-CoA isomerase) (Delta(3),Delta(2)-enoyl-CoA isomerase) (D3,D2-enoyl-CoA isomerase) (Dodecenoyl-CoA isomerase) Mus musculus (Mouse) fatty acid beta-oxidation [GO:0006635] GO:0004165; GO:0005739; GO:0005743; GO:0005759; GO:0006635; GO:0016863; GO:0042802 24853 XM_044323199.1 3 0 0 15 21 P22897 2.95e-56 Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0001618; GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 24854 XM_044323199.1 3 0 0 15 21 P22897 5.87e-53 Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0001618; GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 24855 XM_044323199.1 3 0 0 15 21 P22897 1.84e-52 Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0001618; GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 24856 XM_044323199.1 3 0 0 15 21 P22897 1.06e-44 Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0001618; GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 24857 XM_044323199.1 3 0 0 15 21 P22897 1.22e-43 Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0001618; GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 24858 XM_044323199.1 3 0 0 15 21 P22897 4.02e-35 Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0001618; GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 24859 XM_044323199.1 3 0 0 15 21 P22897 2.58e-31 Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0001618; GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 24860 XM_044323199.1 3 0 0 15 21 P22897 5.74e-26 Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0001618; GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 24861 XM_044323199.1 3 0 0 15 21 P22897 1.95e-25 Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0001618; GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 24862 XM_044323199.1 3 0 0 15 21 P22897 7.69e-25 Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0001618; GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 24863 XM_044323199.1 3 0 0 15 21 P22897 6.06e-22 Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0001618; GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 24864 XR_006397741.1 0 0 6 4 0 NA NA NA NA NA NA 24865 XM_029351255.2 13608 13041 11607 9756 7112 Q8CFN2 1.79e-109 Cell division control protein 42 homolog (EC 3.6.5.2) Rattus norvegicus (Rat) actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; cardiac conduction system development [GO:0003161]; cardiac neural crest cell migration involved in outflow tract morphogenesis [GO:0003253]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cellular response to type II interferon [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; embryonic heart tube development [GO:0035050]; endocytosis [GO:0006897]; endothelin receptor signaling pathway involved in heart process [GO:0086101]; establishment of cell polarity [GO:0030010]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment of localization in cell [GO:0051649]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; establishment or maintenance of cell polarity [GO:0007163]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; modification of synaptic structure [GO:0099563]; negative regulation of protein-containing complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; nucleus localization [GO:0051647]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pinocytosis [GO:0048549]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of exocytosis [GO:0017157]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of postsynapse organization [GO:0099175]; regulation of protein binding [GO:0043393]; regulation of stress fiber assembly [GO:0051492]; response to glucose [GO:0009749]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; viral RNA genome replication [GO:0039694] GO:0000139; GO:0000322; GO:0002040; GO:0003161; GO:0003253; GO:0003924; GO:0003925; GO:0005525; GO:0005737; GO:0005815; GO:0005829; GO:0005886; GO:0005911; GO:0006468; GO:0006897; GO:0006911; GO:0007015; GO:0007030; GO:0007088; GO:0007097; GO:0007163; GO:0007229; GO:0008104; GO:0009749; GO:0010591; GO:0010592; GO:0016020; GO:0017119; GO:0017157; GO:0019901; GO:0030010; GO:0030036; GO:0030141; GO:0030175; GO:0030307; GO:0030335; GO:0030496; GO:0030742; GO:0031252; GO:0031256; GO:0031258; GO:0031274; GO:0031333; GO:0031435; GO:0031996; GO:0032427; GO:0032467; GO:0032488; GO:0032991; GO:0034191; GO:0034329; GO:0034332; GO:0035050; GO:0035088; GO:0036336; GO:0036464; GO:0038189; GO:0039694; GO:0042802; GO:0042995; GO:0043005; GO:0043025; GO:0043085; GO:0043197; GO:0043393; GO:0043410; GO:0043525; GO:0043552; GO:0045177; GO:0045198; GO:0045335; GO:0045740; GO:0046330; GO:0046847; GO:0048549; GO:0048664; GO:0051233; GO:0051489; GO:0051491; GO:0051492; GO:0051496; GO:0051647; GO:0051649; GO:0051683; GO:0051835; GO:0051988; GO:0060047; GO:0060501; GO:0060661; GO:0060997; GO:0061630; GO:0071346; GO:0071944; GO:0072384; GO:0072686; GO:0086101; GO:0090135; GO:0090316; GO:0098685; GO:0098978; GO:0099159; GO:0099175; GO:0099563; GO:1900026; GO:2000251 24866 XM_029349703.2 33 18 16 36 31 B0BM95 4.28e-49 Actin maturation protease (EC 3.4.11.-) (Actin aminopeptidase ACTMAP) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) protein initiator methionine removal involved in protein maturation [GO:0035551] GO:0004177; GO:0035551 24867 XM_044309573.1 3 0 0 12 9 NA NA NA NA NA NA 24868 XM_044316529.1 2 11 13 9 1 NA NA NA NA NA NA 24869 XM_044329107.1 22113 23270 18833 28424 26414 Q61879 0 Myosin-10 (Cellular myosin heavy chain, type B) (Myosin heavy chain 10) (Myosin heavy chain, non-muscle IIb) (Non-muscle myosin heavy chain B) (NMMHC-B) (Non-muscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; actin filament bundle assembly [GO:0051017]; actin filament bundle distribution [GO:0070650]; actin filament-based movement [GO:0030048]; actomyosin structure organization [GO:0031032]; adult heart development [GO:0007512]; aorta development [GO:0035904]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; brain development [GO:0007420]; cardiac muscle cell proliferation [GO:0060038]; cardiac myofibril assembly [GO:0055003]; cardiac septum development [GO:0003279]; cell adhesion [GO:0007155]; cerebellar Purkinje cell layer development [GO:0021680]; coronary vasculature development [GO:0060976]; exocytosis [GO:0006887]; fourth ventricle development [GO:0021592]; heart development [GO:0007507]; in utero embryonic development [GO:0001701]; lateral ventricle development [GO:0021670]; mitotic cytokinesis [GO:0000281]; modification of postsynaptic actin cytoskeleton [GO:0098885]; myofibril assembly [GO:0030239]; neuromuscular process controlling balance [GO:0050885]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; nuclear migration [GO:0007097]; plasma membrane repair [GO:0001778]; positive regulation of protein secretion [GO:0050714]; postsynaptic actin cytoskeleton organization [GO:0098974]; regulation of cell shape [GO:0008360]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; retina development in camera-type eye [GO:0060041]; substrate-dependent cell migration, cell extension [GO:0006930]; third ventricle development [GO:0021678]; ventricular cardiac muscle cell development [GO:0055015] GO:0000146; GO:0000281; GO:0001701; GO:0001725; GO:0001764; GO:0001778; GO:0003279; GO:0005516; GO:0005524; GO:0005737; GO:0005819; GO:0005829; GO:0005844; GO:0005903; GO:0005938; GO:0006887; GO:0006930; GO:0007097; GO:0007155; GO:0007409; GO:0007411; GO:0007420; GO:0007507; GO:0007512; GO:0008360; GO:0009898; GO:0016459; GO:0016460; GO:0016528; GO:0021592; GO:0021670; GO:0021678; GO:0021680; GO:0030027; GO:0030036; GO:0030048; GO:0030239; GO:0030424; GO:0030426; GO:0030496; GO:0031032; GO:0031175; GO:0031594; GO:0032154; GO:0032982; GO:0035613; GO:0035904; GO:0042641; GO:0042802; GO:0043005; GO:0043025; GO:0043197; GO:0043531; GO:0048027; GO:0050714; GO:0050885; GO:0051015; GO:0051017; GO:0055003; GO:0055015; GO:0060038; GO:0060041; GO:0060976; GO:0070650; GO:0097513; GO:0098871; GO:0098885; GO:0098974; GO:0098978; GO:1905274 24870 XM_029324821.2 1162 928 268 845 443 Q8R035 8.59e-33 Peptidyl-tRNA hydrolase ICT1, mitochondrial (EC 3.1.1.29) (39S ribosomal protein L58, mitochondrial) (MRP-L58) (Immature colon carcinoma transcript 1 protein homolog) Mus musculus (Mouse) mitochondrial translation [GO:0032543]; mitochondrial translational termination [GO:0070126] GO:0004045; GO:0005654; GO:0005739; GO:0005743; GO:0005762; GO:0005886; GO:0016150; GO:0032543; GO:0070126 24871 XM_029337048.2 371 259 256 230 365 NA NA NA NA NA NA 24872 XM_044313232.1 0 102 0 88 262 NA NA NA NA NA NA 24873 XR_006394459.1 374 250 128 266 337 NA NA NA NA NA NA 24874 XM_029355942.2 58 66 39 69 147 Q9H8P0 9.31e-37 Polyprenol reductase (EC 1.3.1.94) (3-oxo-5-alpha-steroid 4-dehydrogenase 3) (EC 1.3.1.22) (Steroid 5-alpha-reductase 2-like) (Steroid 5-alpha-reductase 3) (S5AR 3) (SR type 3) Homo sapiens (Human) androgen biosynthetic process [GO:0006702]; dolichol biosynthetic process [GO:0019408]; dolichol metabolic process [GO:0019348]; dolichol-linked oligosaccharide biosynthetic process [GO:0006488]; dolichyl diphosphate biosynthetic process [GO:0006489]; polyprenol catabolic process [GO:0016095] GO:0003865; GO:0005783; GO:0005789; GO:0006488; GO:0006489; GO:0006702; GO:0016095; GO:0016628; GO:0019348; GO:0019408; GO:0047751; GO:0102389 24875 XM_029327005.2 29 20 12 66 12 NA NA NA NA NA NA 24876 XM_029326204.1 243 0 168 84 19 NA NA NA NA NA NA 24877 XM_044328908.1 128 34 10 18 33 O88783 1.29e-23 Coagulation factor V (Activated protein C cofactor) [Cleaved into: Coagulation factor V heavy chain; Coagulation factor V light chain] Mus musculus (Mouse) blood circulation [GO:0008015]; blood coagulation [GO:0007596]; proteolysis [GO:0006508]; response to vitamin K [GO:0032571]; zymogen activation [GO:0031638] GO:0005507; GO:0005576; GO:0005615; GO:0005783; GO:0005794; GO:0006508; GO:0007596; GO:0008015; GO:0031091; GO:0031638; GO:0032571 24878 XM_029323403.2 637 426 468 621 689 NA NA NA NA NA NA 24879 XM_044313957.1 46 77 116 27 212 NA NA NA NA NA NA 24880 XM_044317360.1 969 574 482 1031 1763 NA NA NA NA NA NA 24881 XM_044317637.1 1820 764 949 1057 1399 C0H8I2 9.96e-92 N-lysine methyltransferase setd6 (EC 2.1.1.-) (SET domain-containing protein 6) Salmo salar (Atlantic salmon) negative regulation of NF-kappaB transcription factor activity [GO:0032088]; peptidyl-lysine monomethylation [GO:0018026]; regulation of inflammatory response [GO:0050727] GO:0005634; GO:0016279; GO:0018026; GO:0032088; GO:0050727 24882 XM_029348142.2 3 21 8 7 8 NA NA NA NA NA NA 24883 XM_044326609.1 0 0 0 0 29 Q91ZV7 3.46e-51 Plexin domain-containing protein 1 (Tumor endothelial marker 7) Mus musculus (Mouse) spinal cord development [GO:0021510] GO:0005737; GO:0005886; GO:0005923; GO:0021510; GO:0030425; GO:0043025; GO:0043235 24884 XM_029343449.2 2189 1242 919 1641 1610 Q4QQV8 2.01e-79 Charged multivesicular body protein 5 (Chromatin-modifying protein 5) Rattus norvegicus (Rat) autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; endosome to lysosome transport [GO:0008333]; late endosome to lysosome transport [GO:1902774]; late endosome to vacuole transport via multivesicular body sorting pathway [GO:0032511]; lysosome organization [GO:0007040]; midbody abscission [GO:0061952]; mitotic metaphase plate congression [GO:0007080]; multivesicular body sorting pathway [GO:0071985]; negative regulation of cell death [GO:0060548]; nuclear membrane reassembly [GO:0031468]; nucleus organization [GO:0006997]; plasma membrane repair [GO:0001778]; protein transport [GO:0015031]; regulation of centrosome duplication [GO:0010824]; regulation of mitotic spindle assembly [GO:1901673]; regulation of receptor recycling [GO:0001919]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; vesicle budding from membrane [GO:0006900]; viral budding [GO:0046755]; viral budding from plasma membrane [GO:0046761]; viral budding via host ESCRT complex [GO:0039702] GO:0000421; GO:0000776; GO:0001778; GO:0001919; GO:0005634; GO:0005643; GO:0005765; GO:0005771; GO:0005828; GO:0005829; GO:0005886; GO:0006900; GO:0006914; GO:0006997; GO:0007040; GO:0007080; GO:0008333; GO:0010824; GO:0015031; GO:0030496; GO:0031468; GO:0032511; GO:0032585; GO:0039702; GO:0043162; GO:0046755; GO:0046761; GO:0060548; GO:0061952; GO:0071222; GO:0071225; GO:0071985; GO:0097352; GO:1901673; GO:1902774; GO:1904930 24885 XM_029330234.2 8 1 6 1 121 Q6PCN7 1.93e-176 Helicase-like transcription factor (EC 2.3.2.27) (EC 3.6.4.-) (P113) (RING-type E3 ubiquitin transferase HLTF) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) Mus musculus (Mouse) DNA repair [GO:0006281]; mRNA transcription by RNA polymerase II [GO:0042789]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of neurogenesis [GO:0050767] GO:0003677; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0006281; GO:0008094; GO:0008270; GO:0016363; GO:0016818; GO:0031625; GO:0042789; GO:0045944; GO:0050767; GO:0061630; GO:0090575; GO:0140658 24886 XM_029330234.2 8 1 6 1 121 Q6PCN7 5.82e-23 Helicase-like transcription factor (EC 2.3.2.27) (EC 3.6.4.-) (P113) (RING-type E3 ubiquitin transferase HLTF) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) Mus musculus (Mouse) DNA repair [GO:0006281]; mRNA transcription by RNA polymerase II [GO:0042789]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of neurogenesis [GO:0050767] GO:0003677; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0006281; GO:0008094; GO:0008270; GO:0016363; GO:0016818; GO:0031625; GO:0042789; GO:0045944; GO:0050767; GO:0061630; GO:0090575; GO:0140658 24887 XM_044309441.1 20 18 43 37 107 Q15485 7.31e-77 Ficolin-2 (37 kDa elastin-binding protein) (Collagen/fibrinogen domain-containing protein 2) (EBP-37) (Ficolin-B) (Ficolin-beta) (Hucolin) (L-ficolin) (Serum lectin p35) Homo sapiens (Human) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; positive regulation of opsonization [GO:1903028]; proteolysis [GO:0006508]; recognition of apoptotic cell [GO:0043654] GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005576; GO:0005581; GO:0005615; GO:0006508; GO:0008228; GO:0009897; GO:0042802; GO:0043394; GO:0043654; GO:0046872; GO:0048306; GO:0050829; GO:0050830; GO:0062023; GO:0070062; GO:0072562; GO:0097367; GO:1903028; GO:1905370; GO:2001065 24888 XM_044329267.1 300 235 275 825 349 Q5RBF1 4.12e-124 NAD-dependent protein deacetylase sirtuin-2 (EC 2.3.1.286) (NAD-dependent protein defatty-acylase sirtuin-2) (EC 2.3.1.-) (Regulatory protein SIR2 homolog 2) (SIR2-like protein 2) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cell cycle [GO:0007049]; cell division [GO:0051301]; cellular lipid catabolic process [GO:0044242]; cellular response to caloric restriction [GO:0061433]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hypoxia [GO:0071456]; cellular response to molecule of bacterial origin [GO:0071219]; cellular response to oxidative stress [GO:0034599]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; myelination in peripheral nervous system [GO:0022011]; negative regulation of autophagy [GO:0010507]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of defense response to bacterium [GO:1900425]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of oligodendrocyte progenitor proliferation [GO:0070446]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061428]; peptidyl-lysine deacetylation [GO:0034983]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of attachment of spindle microtubules to kinetochore [GO:0051987]; positive regulation of cell division [GO:0051781]; positive regulation of DNA binding [GO:0043388]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of meiotic nuclear division [GO:0045836]; positive regulation of oocyte maturation [GO:1900195]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia [GO:2000777]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deacetylation [GO:0006476]; protein kinase B signaling [GO:0043491]; regulation of cell cycle [GO:0051726]; regulation of myelination [GO:0031641]; tubulin deacetylation [GO:0090042] GO:0000122; GO:0000792; GO:0003682; GO:0004407; GO:0005634; GO:0005694; GO:0005737; GO:0005813; GO:0005814; GO:0005819; GO:0005829; GO:0005874; GO:0005886; GO:0006476; GO:0007049; GO:0008285; GO:0010507; GO:0010801; GO:0014065; GO:0022011; GO:0030426; GO:0030496; GO:0031641; GO:0032436; GO:0033010; GO:0033270; GO:0033558; GO:0034599; GO:0034979; GO:0034983; GO:0035729; GO:0042177; GO:0042903; GO:0043161; GO:0043204; GO:0043209; GO:0043219; GO:0043220; GO:0043388; GO:0043491; GO:0044224; GO:0044242; GO:0045599; GO:0045836; GO:0045944; GO:0046872; GO:0046970; GO:0048012; GO:0048471; GO:0051301; GO:0051726; GO:0051781; GO:0051987; GO:0061428; GO:0061433; GO:0070403; GO:0070446; GO:0070932; GO:0070933; GO:0071219; GO:0071456; GO:0071872; GO:0072686; GO:0072687; GO:0090042; GO:0097386; GO:0140773; GO:0140774; GO:1900119; GO:1900195; GO:1900425; GO:2000378; GO:2000777 24889 XM_044319988.1 1275 685 584 1126 1175 Q5F363 6.85e-69 Protein Jumonji (Jumonji/ARID domain-containing protein 2) Gallus gallus (Chicken) chromatin remodeling [GO:0006338]; stem cell differentiation [GO:0048863] GO:0003677; GO:0003682; GO:0005634; GO:0006338; GO:0032452; GO:0035097; GO:0035098; GO:0048863 24890 XM_044319988.1 1275 685 584 1126 1175 Q5F363 3.09e-46 Protein Jumonji (Jumonji/ARID domain-containing protein 2) Gallus gallus (Chicken) chromatin remodeling [GO:0006338]; stem cell differentiation [GO:0048863] GO:0003677; GO:0003682; GO:0005634; GO:0006338; GO:0032452; GO:0035097; GO:0035098; GO:0048863 24891 XM_029351160.2 456 540 426 753 505 NA NA NA NA NA NA 24892 XM_044321044.1 2 5 1 7 0 E7FAM5 1.18e-50 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 24893 XR_003823867.2 21 0 22 33 7 NA NA NA NA NA NA 24894 XM_029341851.2 172 0 286 7 22 NA NA NA NA NA NA 24895 XM_029334176.2 0 0 90 167 0 NA NA NA NA NA NA 24896 XR_006394451.1 184 593 278 206 184 NA NA NA NA NA NA 24897 XM_044309151.1 696 690 381 812 454 Q3ZCH9 2.14e-96 Haloacid dehalogenase-like hydrolase domain-containing protein 2 Bos taurus (Bovine) dephosphorylation [GO:0016311] GO:0016311; GO:0016791; GO:0019899; GO:0046872 24898 XM_044321123.1 0 0 0 0 10 Q96DM1 3.64e-55 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 24899 XM_044321123.1 0 0 0 0 10 Q96DM1 3.64e-55 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 24900 XR_006394790.1 18 13 29 0 17 NA NA NA NA NA NA 24901 XM_029345452.2 0 0 14 13 34 NA NA NA NA NA NA 24902 XR_006393886.1 45 0 8 0 69 NA NA NA NA NA NA 24903 XM_044325813.1 64 25 3 68 100 NA NA NA NA NA NA 24904 XR_006397474.1 82 46 89 104 244 NA NA NA NA NA NA 24905 XM_029358423.2 0 35 0 82 88 NA NA NA NA NA NA 24906 XR_006395031.1 78 194 106 120 288 NA NA NA NA NA NA 24907 XR_006393305.1 0 3 0 4 17 NA NA NA NA NA NA 24908 XM_044323683.1 0 0 0 33 0 NA NA NA NA NA NA 24909 XM_029333609.2 70 7 44 15 28 A2VDD2 4.73e-24 Dynein light chain Tctex-type 5-B (Tctex1 domain-containing protein 1-B) Xenopus laevis (African clawed frog) NA NA 24910 XM_029350897.2 0 0 3 0 6 P27080 8.81e-123 ADP,ATP carrier protein (ADP/ATP translocase) (Adenine nucleotide translocator) (ANT) Chlamydomonas reinhardtii (Chlamydomonas smithii) mitochondrial ADP transmembrane transport [GO:0140021]; mitochondrial ATP transmembrane transport [GO:1990544] GO:0005471; GO:0005743; GO:0140021; GO:1990544 24911 XR_006398013.1 6 1 134 18 8 NA NA NA NA NA NA 24912 XM_029326883.2 94 76 102 84 13 NA NA NA NA NA NA 24913 XR_006395250.1 27 69 0 52 0 NA NA NA NA NA NA 24914 XM_029329653.2 696 229 351 389 298 B2RRD7 3.09e-156 Peregrin (Bromodomain and PHD finger-containing protein 1) Mus musculus (Mouse) chromatin organization [GO:0006325]; common myeloid progenitor cell proliferation [GO:0035726]; histone H3-K23 acetylation [GO:0043972]; neural tube formation [GO:0001841]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA-templated transcription [GO:0006355]; regulation of fibroblast proliferation [GO:0048145]; regulation of transcription by RNA polymerase II [GO:0006357]; vasculogenesis [GO:0001570] GO:0000123; GO:0001570; GO:0001841; GO:0003677; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0006325; GO:0006355; GO:0006357; GO:0010698; GO:0035726; GO:0043972; GO:0043995; GO:0043996; GO:0043997; GO:0045893; GO:0046872; GO:0048145; GO:0070776 24915 XM_029329653.2 696 229 351 389 298 B2RRD7 1.93e-85 Peregrin (Bromodomain and PHD finger-containing protein 1) Mus musculus (Mouse) chromatin organization [GO:0006325]; common myeloid progenitor cell proliferation [GO:0035726]; histone H3-K23 acetylation [GO:0043972]; neural tube formation [GO:0001841]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA-templated transcription [GO:0006355]; regulation of fibroblast proliferation [GO:0048145]; regulation of transcription by RNA polymerase II [GO:0006357]; vasculogenesis [GO:0001570] GO:0000123; GO:0001570; GO:0001841; GO:0003677; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0006325; GO:0006355; GO:0006357; GO:0010698; GO:0035726; GO:0043972; GO:0043995; GO:0043996; GO:0043997; GO:0045893; GO:0046872; GO:0048145; GO:0070776 24916 XM_029329653.2 696 229 351 389 298 B2RRD7 1.97e-38 Peregrin (Bromodomain and PHD finger-containing protein 1) Mus musculus (Mouse) chromatin organization [GO:0006325]; common myeloid progenitor cell proliferation [GO:0035726]; histone H3-K23 acetylation [GO:0043972]; neural tube formation [GO:0001841]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA-templated transcription [GO:0006355]; regulation of fibroblast proliferation [GO:0048145]; regulation of transcription by RNA polymerase II [GO:0006357]; vasculogenesis [GO:0001570] GO:0000123; GO:0001570; GO:0001841; GO:0003677; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0006325; GO:0006355; GO:0006357; GO:0010698; GO:0035726; GO:0043972; GO:0043995; GO:0043996; GO:0043997; GO:0045893; GO:0046872; GO:0048145; GO:0070776 24917 XM_029335039.2 56 2 7 8 101 NA NA NA NA NA NA 24918 XM_029334223.2 294 202 173 249 254 Q2KI92 2.94e-48 Mitochondrial inner membrane protease subunit 2 (EC 3.4.21.-) (IMP2-like protein) Bos taurus (Bovine) blood circulation [GO:0008015]; brain development [GO:0007420]; cellular response to DNA damage stimulus [GO:0006974]; cerebellum vasculature development [GO:0061300]; mitochondrial respiratory chain complex assembly [GO:0033108]; ovarian follicle development [GO:0001541]; ovulation [GO:0030728]; protein processing involved in protein targeting to mitochondrion [GO:0006627]; respiratory electron transport chain [GO:0022904]; signal peptide processing [GO:0006465]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801] GO:0001541; GO:0004175; GO:0004252; GO:0006465; GO:0006627; GO:0006801; GO:0006974; GO:0007283; GO:0007420; GO:0008015; GO:0022904; GO:0030728; GO:0033108; GO:0042720; GO:0061300 24919 XM_029330833.2 22 1025 159 54 0 NA NA NA NA NA NA 24920 XM_029336083.2 191 98 147 76 55 Q90867 1.3e-76 Hepatocyte nuclear factor 1-alpha (HNF-1-alpha) (HNF-1A) (Transcription factor 1) (TCF-1) Gallus gallus (Chicken) glucose homeostasis [GO:0042593]; insulin secretion [GO:0030073]; liver development [GO:0001889]; pancreas development [GO:0031016]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000976; GO:0000978; GO:0000981; GO:0001889; GO:0003700; GO:0005634; GO:0006357; GO:0030073; GO:0031016; GO:0032991; GO:0042593; GO:0045893 24921 XM_044322671.1 0 0 0 3 13 NA NA NA NA NA NA 24922 XM_029348638.2 721 634 541 703 999 P30260 0 Cell division cycle protein 27 homolog (Anaphase-promoting complex subunit 3) (APC3) (CDC27 homolog) (CDC27Hs) (H-NUC) Homo sapiens (Human) anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; metaphase/anaphase transition of mitotic cell cycle [GO:0007091]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; protein K11-linked ubiquitination [GO:0070979]; protein ubiquitination [GO:0016567]; regulation of meiotic cell cycle [GO:0051445]; regulation of mitotic cell cycle [GO:0007346] GO:0005634; GO:0005654; GO:0005680; GO:0005737; GO:0005813; GO:0005819; GO:0005829; GO:0007091; GO:0007346; GO:0016567; GO:0019903; GO:0031145; GO:0045842; GO:0051301; GO:0051445; GO:0070979; GO:0072686 24923 XM_044319864.1 15 8 0 5 6 NA NA NA NA NA NA 24924 XM_029331694.2 1565 1742 1346 2218 1778 NA NA NA NA NA NA 24925 XM_029336614.2 273 844 72 437 412 NA NA NA NA NA NA 24926 XM_029351529.2 15 10 26 0 23 NA NA NA NA NA NA 24927 XM_044307977.1 0 0 0 7 0 NA NA NA NA NA NA 24928 XM_029338429.2 174 549 492 540 239 Q3KP44 1.18e-24 Ankyrin repeat domain-containing protein 55 Homo sapiens (Human) NA NA 24929 XR_003824568.2 264 163 154 185 360 NA NA NA NA NA NA 24930 XM_044309505.1 11 44 0 4 11 Q9UGM3 1.75e-55 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 24931 XM_044309505.1 11 44 0 4 11 Q9UGM3 2.14e-53 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 24932 XM_044309505.1 11 44 0 4 11 Q9UGM3 1.54e-52 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 24933 XM_044309505.1 11 44 0 4 11 Q9UGM3 1.55e-52 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 24934 XM_044309505.1 11 44 0 4 11 Q9UGM3 2.61e-52 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 24935 XM_044309505.1 11 44 0 4 11 Q9UGM3 3.34e-52 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 24936 XM_044309505.1 11 44 0 4 11 Q9UGM3 3.61e-52 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 24937 XM_044309505.1 11 44 0 4 11 Q9UGM3 8.66e-52 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 24938 XM_044309505.1 11 44 0 4 11 Q9UGM3 9.63e-52 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 24939 XM_044309505.1 11 44 0 4 11 Q9UGM3 1.02e-51 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 24940 XM_044309505.1 11 44 0 4 11 Q9UGM3 2.02e-51 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 24941 XM_044309505.1 11 44 0 4 11 Q9UGM3 2.2e-51 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 24942 XM_044309505.1 11 44 0 4 11 Q9UGM3 2.29e-26 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 24943 XM_044309917.1 12 0 3 0 0 NA NA NA NA NA NA 24944 XR_006393368.1 80 13 63 64 73 P47743 1.77e-48 Metabotropic glutamate receptor 8 (mGluR8) Mus musculus (Mouse) adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway [GO:0007196]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; chemical synaptic transmission [GO:0007268]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; G protein-coupled glutamate receptor signaling pathway [GO:0007216]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of neurotransmitter secretion [GO:0046928]; regulation of synaptic transmission, glutamatergic [GO:0051966]; synaptic transmission, glutamatergic [GO:0035249] GO:0001640; GO:0001642; GO:0004930; GO:0005886; GO:0007193; GO:0007196; GO:0007216; GO:0007268; GO:0008066; GO:0035249; GO:0042734; GO:0043005; GO:0043025; GO:0046928; GO:0048787; GO:0050966; GO:0051966; GO:0098978; GO:0098982; GO:0099171 24945 XM_029342841.2 354 208 252 302 365 Q9NYI0 2.98e-94 PH and SEC7 domain-containing protein 3 (Epididymis tissue protein Li 20mP) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 D) (Exchange factor for ARF6 D) (Hepatocellular carcinoma-associated antigen 67) (Pleckstrin homology and SEC7 domain-containing protein 3) Homo sapiens (Human) regulation of ARF protein signal transduction [GO:0032012] GO:0005085; GO:0014069; GO:0032012; GO:0032587 24946 XM_044327998.1 88 337 126 318 0 NA NA NA NA NA NA 24947 XM_029357509.2 1418 1724 1614 1942 2131 O43581 2.11e-25 Synaptotagmin-7 (IPCA-7) (Prostate cancer-associated protein 7) (Synaptotagmin VII) (SytVII) Homo sapiens (Human) calcium ion regulated lysosome exocytosis [GO:1990927]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; phagocytosis [GO:0006909]; phagosome-lysosome fusion [GO:0090385]; plasma membrane repair [GO:0001778]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; regulation of bone remodeling [GO:0046850]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of glucagon secretion [GO:0070092]; regulation of insulin secretion [GO:0050796]; regulation of phagocytosis [GO:0050764]; regulation of synaptic vesicle endocytosis [GO:1900242]; short-term synaptic potentiation [GO:1990926]; synaptic vesicle recycling [GO:0036465]; vesicle-mediated cholesterol transport [GO:0090119]; vesicle-mediated transport [GO:0016192] GO:0000149; GO:0001778; GO:0001786; GO:0005509; GO:0005516; GO:0005544; GO:0005546; GO:0005764; GO:0005765; GO:0005777; GO:0005778; GO:0005829; GO:0005886; GO:0006909; GO:0008021; GO:0014059; GO:0016192; GO:0017156; GO:0017158; GO:0019905; GO:0030276; GO:0030670; GO:0030672; GO:0031045; GO:0032009; GO:0036465; GO:0042734; GO:0042995; GO:0045956; GO:0046850; GO:0048791; GO:0050764; GO:0050796; GO:0070062; GO:0070092; GO:0070382; GO:0071277; GO:0090119; GO:0090385; GO:0098686; GO:1900242; GO:1990926; GO:1990927 24948 XR_003826424.2 133 93 103 143 120 NA NA NA NA NA NA 24949 XM_029357082.2 31 31 83 51 140 O43301 0 Heat shock 70 kDa protein 12A Homo sapiens (Human) NA GO:0005524; GO:0005634; GO:0005737; GO:0070062 24950 XM_029343387.2 356 241 214 374 498 Q4R4V2 4.48e-74 Protein phosphatase 1G (EC 3.1.3.16) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) protein dephosphorylation [GO:0006470] GO:0005737; GO:0006470; GO:0016020; GO:0017018; GO:0046872 24951 XM_029343387.2 356 241 214 374 498 Q4R4V2 2.97e-29 Protein phosphatase 1G (EC 3.1.3.16) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) protein dephosphorylation [GO:0006470] GO:0005737; GO:0006470; GO:0016020; GO:0017018; GO:0046872 24952 XM_044313668.1 36 2 127 6 1 C3VPR6 5.97e-23 Protein NLRC5 Mus musculus (Mouse) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of type II interferon-mediated signaling pathway [GO:0060335]; regulation of kinase activity [GO:0043549]; response to bacterium [GO:0009617] GO:0000978; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0009617; GO:0032088; GO:0035556; GO:0043549; GO:0045087; GO:0045345; GO:0045944; GO:0051607; GO:0060335; GO:0060339; GO:0060340 24953 XM_029331001.2 41 63 43 34 35 NA NA NA NA NA NA 24954 XM_044326996.1 0 58 0 8 127 B8VIW9 2.28e-113 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 24955 XM_044324615.1 3 0 0 10 18 Q09575 6.33e-45 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 24956 XM_029325905.2 15 10 25 16 54 NA NA NA NA NA NA 24957 XR_003824600.2 0 0 0 12 0 NA NA NA NA NA NA 24958 XM_029340757.2 59 0 31 0 12 P21674 1.07e-37 Follistatin (FS) (Activin-binding protein) Rattus norvegicus (Rat) ameloblast differentiation [GO:0036305]; BMP signaling pathway [GO:0030509]; cell differentiation [GO:0030154]; cellular response to growth factor stimulus [GO:0071363]; female gonad development [GO:0008585]; gamete generation [GO:0007276]; hair follicle morphogenesis [GO:0031069]; hematopoietic progenitor cell differentiation [GO:0002244]; keratinocyte proliferation [GO:0043616]; negative regulation of activin receptor signaling pathway [GO:0032926]; negative regulation of cell differentiation [GO:0045596]; negative regulation of epithelial cell differentiation [GO:0030857]; negative regulation of follicle-stimulating hormone secretion [GO:0046882]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis of dentin-containing tooth [GO:0042475]; pattern specification process [GO:0007389]; positive regulation of hair follicle development [GO:0051798]; regulation of BMP signaling pathway [GO:0030510]; response to organic cyclic compound [GO:0014070]; skeletal system development [GO:0001501] GO:0000122; GO:0001501; GO:0002244; GO:0005615; GO:0005634; GO:0005737; GO:0007276; GO:0007389; GO:0008585; GO:0014070; GO:0030154; GO:0030509; GO:0030510; GO:0030857; GO:0031069; GO:0032926; GO:0036305; GO:0038102; GO:0042475; GO:0043395; GO:0043616; GO:0045596; GO:0046882; GO:0048185; GO:0051798; GO:0071363 24959 XM_029339993.2 223 194 4 170 14 Q6AXN4 5.07e-84 Nucleoporin NDC1 (Transmembrane protein 48) Rattus norvegicus (Rat) homologous chromosome pairing at meiosis [GO:0007129]; mRNA transport [GO:0051028]; nuclear pore complex assembly [GO:0051292]; nuclear pore localization [GO:0051664]; nuclear pore organization [GO:0006999]; protein transport [GO:0015031]; spermatogenesis [GO:0007283] GO:0005635; GO:0005643; GO:0005737; GO:0006999; GO:0007129; GO:0007283; GO:0015031; GO:0017056; GO:0030674; GO:0031965; GO:0051028; GO:0051292; GO:0051664; GO:0070762 24960 XR_006397545.1 4 0 0 9 0 NA NA NA NA NA NA 24961 XM_044320864.1 0 36 0 201 3 NA NA NA NA NA NA 24962 XR_006391957.1 0 0 0 0 16 NA NA NA NA NA NA 24963 XM_029356288.2 981 706 434 788 289 NA NA NA NA NA NA 24964 XM_044312000.1 0 0 0 9 10 NA NA NA NA NA NA 24965 XR_006392563.1 0 3 9 0 37 NA NA NA NA NA NA 24966 XM_029350084.2 3 6 11 21 12 NA NA NA NA NA NA 24967 XR_006397000.1 20 0 3 46 5 NA NA NA NA NA NA 24968 XM_029339447.2 0 4 3 0 105 O95671 4.55e-56 Probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein [Includes: dTTP/UTP pyrophosphatase (dTTPase/UTPase) (EC 3.6.1.9) (Nucleoside triphosphate pyrophosphatase) (Nucleotide pyrophosphatase) (Nucleotide PPase); N-acetylserotonin O-methyltransferase-like protein (ASMTL) (EC 2.1.1.-)] Homo sapiens (Human) methylation [GO:0032259]; nucleotide metabolic process [GO:0009117] GO:0005829; GO:0008171; GO:0009117; GO:0032259; GO:0036218; GO:0036221; GO:0047429 24969 XM_044320172.1 13 0 1 87 84 Q5DTN8 9.24e-50 Janus kinase and microtubule-interacting protein 3 (Neuroendocrine long coiled-coil protein 2) Mus musculus (Mouse) NA GO:0005794; GO:0008017; GO:0019900 24970 XM_029341491.2 0 0 0 3 13 NA NA NA NA NA NA 24971 XM_029340873.2 299 148 75 179 234 NA NA NA NA NA NA 24972 XM_044310237.1 0 0 6 7 12 NA NA NA NA NA NA 24973 XM_029351886.2 670 483 564 427 306 Q91857 4.78e-177 Transcription initiation factor TFIID subunit 6 (xTAF6) (Transcription initiation factor TFIID 60 kDa subunit) (TAF(II)60) (TAFII-60) (TAFII60) (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII70) Xenopus laevis (African clawed frog) transcription initiation at RNA polymerase II promoter [GO:0006367] GO:0000124; GO:0005669; GO:0006367; GO:0016251; GO:0046695; GO:0046982; GO:0071339 24974 XM_044320102.1 45 0 10 0 22 Q5U243 2.93e-139 CAP-Gly domain-containing linker protein 3 (Cytoplasmic linker protein 170-related 59 kDa protein) (CLIP-170-related 59 kDa protein) (CLIPR-59) Xenopus laevis (African clawed frog) NA GO:0005795 24975 XM_029345834.2 1300 1637 473 1413 1594 Q62277 2.7e-34 Synaptophysin (BM89 antigen) (Major synaptic vesicle protein p38) Mus musculus (Mouse) cellular response to organic substance [GO:0071310]; chemical synaptic transmission [GO:0007268]; endocytosis [GO:0006897]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of opioid receptor signaling pathway [GO:2000474]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic vesicle exocytosis [GO:2000300]; synaptic vesicle endocytosis [GO:0048488] GO:0000149; GO:0006897; GO:0007268; GO:0008021; GO:0014069; GO:0015485; GO:0016020; GO:0017075; GO:0019904; GO:0030672; GO:0031594; GO:0032991; GO:0042169; GO:0042734; GO:0042802; GO:0043005; GO:0043195; GO:0043229; GO:0044306; GO:0044309; GO:0044877; GO:0045202; GO:0048168; GO:0048169; GO:0048172; GO:0048471; GO:0048488; GO:0048786; GO:0060076; GO:0060203; GO:0071310; GO:0098685; GO:0098793; GO:2000300; GO:2000474 24976 XR_006396110.1 403 8 36 35 41 NA NA NA NA NA NA 24977 XM_044326864.1 451 162 95 174 437 NA NA NA NA NA NA 24978 XM_044312635.1 0 2 38 1 452 NA NA NA NA NA NA 24979 XM_044322605.1 5 1 2 12 11 NA NA NA NA NA NA 24980 XM_044307718.1 156 113 54 176 227 Q6RT24 2.5e-115 Centromere-associated protein E (Centromere protein E) (CENP-E) (Kinesin superfamily protein 10) (KIF10) (Motor domain of KIF10) Mus musculus (Mouse) attachment of mitotic spindle microtubules to kinetochore [GO:0051315]; attachment of spindle microtubules to kinetochore [GO:0008608]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; establishment of protein localization [GO:0045184]; kinetochore assembly [GO:0051382]; lateral attachment of mitotic spindle microtubules to kinetochore [GO:0099607]; metaphase plate congression [GO:0051310]; microtubule plus-end directed mitotic chromosome migration [GO:0099606]; microtubule-based movement [GO:0007018]; mitotic cell cycle [GO:0000278]; mitotic chromosome movement towards spindle pole [GO:0007079]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly checkpoint signaling [GO:0007094]; mitotic spindle organization [GO:0007052]; positive regulation of attachment of spindle microtubules to kinetochore [GO:0051987]; positive regulation of chromosome segregation [GO:0051984]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; positive regulation of protein kinase activity [GO:0045860]; regulation of developmental process [GO:0050793]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of mitotic nuclear division [GO:0007088]; regulation of protein stability [GO:0031647]; spindle assembly involved in female meiosis I [GO:0007057] GO:0000278; GO:0000775; GO:0000776; GO:0000779; GO:0000940; GO:0003777; GO:0005524; GO:0005634; GO:0005694; GO:0005737; GO:0005828; GO:0005874; GO:0007018; GO:0007052; GO:0007057; GO:0007059; GO:0007079; GO:0007080; GO:0007088; GO:0007094; GO:0008017; GO:0008574; GO:0008608; GO:0015630; GO:0019901; GO:0030071; GO:0030496; GO:0031647; GO:0043231; GO:0043515; GO:0045171; GO:0045184; GO:0045842; GO:0045860; GO:0050793; GO:0051233; GO:0051301; GO:0051310; GO:0051315; GO:0051382; GO:0051984; GO:0051987; GO:0072686; GO:0099606; GO:0099607; GO:1990023 24981 XM_044326867.1 14 47 14 81 41 NA NA NA NA NA NA 24982 XM_029336586.2 39 54 57 89 165 NA NA NA NA NA NA 24983 XM_029349162.2 492 332 303 402 570 Q12788 0 Transducin beta-like protein 3 (WD repeat-containing protein SAZD) Homo sapiens (Human) endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000480]; endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000472] GO:0000472; GO:0000480; GO:0003723; GO:0005654; GO:0005730; GO:0030686; GO:0032040; GO:0034511 24984 XM_029345181.2 3376 2085 575 1735 1471 B0JZP3 1.58e-32 Protein THEM6 Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005576 24985 XM_044313188.1 6 31 2 27 12 NA NA NA NA NA NA 24986 XR_006392091.1 0 0 7 0 36 NA NA NA NA NA NA 24987 XM_029347936.2 347 210 238 271 436 Q95LD9 3.38e-41 Aryl hydrocarbon receptor (Ah receptor) (AhR) Delphinapterus leucas (Beluga whale) cAMP-mediated signaling [GO:0019933]; cell cycle [GO:0007049]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; circadian regulation of gene expression [GO:0032922]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of T cell mediated immune response to tumor cell [GO:0002841]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of adaptive immune response [GO:0002819]; regulation of B cell proliferation [GO:0030888]; response to toxic substance [GO:0009636]; response to xenobiotic stimulus [GO:0009410] GO:0001094; GO:0001223; GO:0002819; GO:0002841; GO:0004879; GO:0005634; GO:0005737; GO:0005829; GO:0007049; GO:0009410; GO:0009636; GO:0017025; GO:0019933; GO:0030888; GO:0032922; GO:0034753; GO:0045892; GO:0045893; GO:0045944; GO:0046982; GO:0051879; GO:0060090; GO:0061629; GO:0070888; GO:0071320; GO:1904322; GO:1904613; GO:1990837 24988 XM_029347971.2 13 1 0 9 26 Q2QRV3 3.49e-106 Alpha-dioxygenase PIOX (EC 1.13.11.92) (Pathogen-induced oxygenase) Oryza sativa subsp. japonica (Rice) (R)-2-hydroxy-alpha-linolenic acid biosynthetic process [GO:1902609]; cell death [GO:0008219]; cellular response to nitric oxide [GO:0071732]; cellular response to reactive oxygen species [GO:0034614]; cellular response to salicylic acid stimulus [GO:0071446]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; fatty acid alpha-oxidation [GO:0001561]; oxylipin biosynthetic process [GO:0031408]; response to abscisic acid [GO:0009737]; systemic acquired resistance [GO:0009627] GO:0001561; GO:0004601; GO:0008219; GO:0009627; GO:0009737; GO:0012511; GO:0016702; GO:0020037; GO:0031408; GO:0034614; GO:0042742; GO:0046872; GO:0050832; GO:0071446; GO:0071732; GO:1902609 24989 XM_029331090.2 51 1 70 45 76 Q9CZX5 1.84e-41 PIN2/TERF1-interacting telomerase inhibitor 1 (67-11-3 protein) (LPTS1) (Liver-related putative tumor suppressor) (Pin2-interacting protein X1) (TRF1-interacting protein 1) Mus musculus (Mouse) mitotic metaphase plate congression [GO:0007080]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; positive regulation of protein localization to nucleolus [GO:1904751]; positive regulation of telomeric DNA binding [GO:1904744]; protein localization to chromosome, telomeric region [GO:0070198]; protein localization to nucleolus [GO:1902570]; regulation of protein stability [GO:0031647]; ribosomal small subunit biogenesis [GO:0042274]; telomere maintenance via telomerase [GO:0007004] GO:0000228; GO:0000776; GO:0000781; GO:0005654; GO:0005730; GO:0005739; GO:0005819; GO:0007004; GO:0007080; GO:0010521; GO:0010972; GO:0031397; GO:0031647; GO:0032211; GO:0042274; GO:0044877; GO:0051974; GO:0070034; GO:0070198; GO:1902570; GO:1904744; GO:1904751 24990 XM_044320549.1 0 0 1 9 13 NA NA NA NA NA NA 24991 XM_029357756.2 1412 911 744 1209 1156 Q99615 3.77e-156 DnaJ homolog subfamily C member 7 (Tetratricopeptide repeat protein 2) (TPR repeat protein 2) Homo sapiens (Human) chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; regulation of cellular response to heat [GO:1900034] GO:0001671; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0006457; GO:0016020; GO:0031072; GO:0051085; GO:0070062; GO:1900034 24992 XM_044320204.1 31 0 0 29 56 NA NA NA NA NA NA 24993 XR_003827347.2 556 394 290 436 649 NA NA NA NA NA NA 24994 XM_029342233.2 125 0 0 0 0 O15350 2.84e-57 Tumor protein p73 (p53-like transcription factor) (p53-related protein) Homo sapiens (Human) cell cycle [GO:0007049]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of lung ciliated cell differentiation [GO:1901248]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein tetramerization [GO:0051262]; regulation of cell cycle [GO:0051726]; regulation of gene expression [GO:0010468]; regulation of mitotic cell cycle [GO:0007346]; regulation of transcription by RNA polymerase II [GO:0006357]; response to organonitrogen compound [GO:0010243]; response to xenobiotic stimulus [GO:0009410] GO:0000785; GO:0000976; GO:0000978; GO:0000981; GO:0001222; GO:0001228; GO:0001822; GO:0002039; GO:0003700; GO:0005634; GO:0005654; GO:0005794; GO:0005829; GO:0006298; GO:0006357; GO:0006974; GO:0007049; GO:0007346; GO:0008285; GO:0008630; GO:0009410; GO:0010243; GO:0010468; GO:0019901; GO:0030054; GO:0042771; GO:0042802; GO:0043065; GO:0043231; GO:0043410; GO:0045665; GO:0045893; GO:0045944; GO:0046872; GO:0048714; GO:0051262; GO:0051726; GO:0060044; GO:0061629; GO:0097371; GO:0140297; GO:1901248 24995 XM_044310512.1 189 15 19 75 267 NA NA NA NA NA NA 24996 XM_044313923.1 36 18 22 5 57 NA NA NA NA NA NA 24997 XM_029351010.2 776 613 326 309 647 Q5R9E1 1.38e-144 Hydroxymethylglutaryl-CoA lyase, mitochondrial (HL) (HMG-CoA lyase) (EC 4.1.3.4) (3-hydroxy-3-methylglutarate-CoA lyase) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) ketone body biosynthetic process [GO:0046951] GO:0004419; GO:0005759; GO:0005777; GO:0046872; GO:0046951 24998 XM_029354653.2 1 240 12 1 7 NA NA NA NA NA NA 24999 XM_044322564.1 109 94 80 259 54 NA NA NA NA NA NA 25000 XM_029332266.2 604 442 438 826 638 Q9CZX2 5.75e-70 Centrosomal protein of 89 kDa (Cep89) (Coiled-coil domain-containing protein 123) Mus musculus (Mouse) chemical synaptic transmission [GO:0007268]; cilium assembly [GO:0060271]; mitochondrion organization [GO:0007005]; non-motile cilium assembly [GO:1905515] GO:0000922; GO:0005758; GO:0005813; GO:0005814; GO:0005829; GO:0005886; GO:0007005; GO:0007268; GO:0031514; GO:0045202; GO:0060271; GO:0097539; GO:0097730; GO:1905515 25001 XR_006393077.1 41 2 25 5 151 NA NA NA NA NA NA 25002 XR_006396655.1 55 4 24 19 133 NA NA NA NA NA NA 25003 XM_044311678.1 69 9 42 0 156 B8VIU6 1.96e-56 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 25004 XM_029336209.2 284 153 312 442 496 Q9UGM6 1.54e-109 Tryptophan--tRNA ligase, mitochondrial (EC 6.1.1.2) ((Mt)TrpRS) (Tryptophanyl-tRNA synthetase) (TrpRS) Homo sapiens (Human) mitochondrial tryptophanyl-tRNA aminoacylation [GO:0070183]; positive regulation of angiogenesis [GO:0045766]; tRNA aminoacylation for protein translation [GO:0006418]; tryptophanyl-tRNA aminoacylation [GO:0006436]; vasculogenesis [GO:0001570] GO:0001570; GO:0004830; GO:0005524; GO:0005654; GO:0005739; GO:0005759; GO:0005886; GO:0006418; GO:0006436; GO:0045766; GO:0070183 25005 XM_044309827.1 5 6 7 14 2 NA NA NA NA NA NA 25006 XM_044316991.1 349 205 84 0 405 NA NA NA NA NA NA 25007 XR_006391639.1 0 0 9 0 0 NA NA NA NA NA NA 25008 XM_044310875.1 25 12 34 30 47 NA NA NA NA NA NA 25009 XM_029345185.2 91 391 469 154 67 NA NA NA NA NA NA 25010 XR_006397463.1 912 643 420 988 822 NA NA NA NA NA NA 25011 XR_006391504.1 37 1 0 0 2 NA NA NA NA NA NA 25012 XM_044313881.1 28 1 0 0 111 NA NA NA NA NA NA 25013 XM_044325802.1 1 22 5 2 27 NA NA NA NA NA NA 25014 XM_029325043.2 6 0 0 1 0 NA NA NA NA NA NA 25015 XM_044326633.1 10 0 1 6 0 NA NA NA NA NA NA 25016 XM_044321055.1 0 0 87 1 161 P23780 0 Beta-galactosidase (EC 3.2.1.23) (Acid beta-galactosidase) (Lactase) Mus musculus (Mouse) cellular carbohydrate metabolic process [GO:0044262]; galactose catabolic process [GO:0019388]; response to cortisone [GO:0051413]; response to Thyroglobulin triiodothyronine [GO:1904016] GO:0004565; GO:0005615; GO:0005737; GO:0005764; GO:0005773; GO:0005794; GO:0016787; GO:0016936; GO:0019388; GO:0042803; GO:0043231; GO:0044262; GO:0051413; GO:1904016 25017 XM_044317478.1 249 147 62 244 265 P0DKB4 8.85e-138 Trans-L-3-hydroxyproline dehydratase (EC 4.2.1.77) (Trans-3-hydroxy-L-proline dehydratase) Saccoglossus kowalevskii (Acorn worm) NA GO:0016836; GO:0050346 25018 XM_029324756.2 9 19 15 9 5 NA NA NA NA NA NA 25019 XM_029341950.2 1356 1165 976 874 1014 A9ULG4 1.84e-58 Lipid droplet-regulating VLDL assembly factor AUP1 (Ancient ubiquitous protein 1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) ER-associated misfolded protein catabolic process [GO:0071712]; lipid droplet formation [GO:0140042]; lipid droplet organization [GO:0034389]; protein localization to lipid droplet [GO:1990044]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0005789; GO:0005811; GO:0030433; GO:0034389; GO:0043130; GO:0071712; GO:0140042; GO:1990044 25020 XM_044323958.1 14 20 22 28 22 NA NA NA NA NA NA 25021 XM_029342963.2 1 10 0 39 19 NA NA NA NA NA NA 25022 XM_044318711.1 302 95 130 110 144 NA NA NA NA NA NA 25023 XM_044308949.1 0 0 9 0 0 NA NA NA NA NA NA 25024 XM_029324140.2 218 109 45 71 114 NA NA NA NA NA NA 25025 XM_044328238.1 9 15 4 10 7 Q6LAF1 6.56e-52 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 25026 XM_029354965.2 776 566 310 419 688 Q5R952 3.56e-140 Nucleolar complex protein 3 homolog (NOC3 protein homolog) (NOC3-like protein) (Nucleolar complex-associated protein 3-like protein) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0005730; GO:0016607 25027 XM_029353377.2 12 0 20 0 25 NA NA NA NA NA NA 25028 XM_044327900.1 57 0 2 9 0 NA NA NA NA NA NA 25029 XR_006392598.1 146 84 93 110 269 NA NA NA NA NA NA 25030 XM_044309768.1 71 38 41 141 83 O75581 0 Low-density lipoprotein receptor-related protein 6 (LRP-6) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; chemical synaptic transmission [GO:0007268]; dopaminergic neuron differentiation [GO:0071542]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001933; GO:0005041; GO:0005102; GO:0005109; GO:0005576; GO:0005783; GO:0005886; GO:0006469; GO:0007204; GO:0007268; GO:0009986; GO:0014029; GO:0014033; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0031410; GO:0031901; GO:0034392; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043434; GO:0044335; GO:0044340; GO:0045121; GO:0045202; GO:0045787; GO:0045893; GO:0045944; GO:0051091; GO:0060070; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072659; GO:0090118; GO:0090244; GO:0098609; GO:1904928; GO:1904948; GO:1904953; GO:1990851; GO:1990909 25031 XM_044309768.1 71 38 41 141 83 O75581 2.72e-171 Low-density lipoprotein receptor-related protein 6 (LRP-6) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; chemical synaptic transmission [GO:0007268]; dopaminergic neuron differentiation [GO:0071542]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001933; GO:0005041; GO:0005102; GO:0005109; GO:0005576; GO:0005783; GO:0005886; GO:0006469; GO:0007204; GO:0007268; GO:0009986; GO:0014029; GO:0014033; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0031410; GO:0031901; GO:0034392; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043434; GO:0044335; GO:0044340; GO:0045121; GO:0045202; GO:0045787; GO:0045893; GO:0045944; GO:0051091; GO:0060070; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072659; GO:0090118; GO:0090244; GO:0098609; GO:1904928; GO:1904948; GO:1904953; GO:1990851; GO:1990909 25032 XM_044323282.1 8 10 12 120 26 NA NA NA NA NA NA 25033 XM_029347815.2 849 856 537 836 704 Q5SSH8 6.21e-69 Neuferricin (Cytochrome b5 domain-containing protein 2) Mus musculus (Mouse) neuron differentiation [GO:0030182]; positive regulation of neuron differentiation [GO:0045666] GO:0005576; GO:0012505; GO:0016020; GO:0020037; GO:0030182; GO:0045666 25034 XM_029346820.2 0 0 0 0 265 Q8IV61 5.3e-135 Ras guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1) Homo sapiens (Human) MAPK cascade [GO:0000165]; positive regulation of GTPase activity [GO:0043547]; Ras protein signal transduction [GO:0007265]; small GTPase mediated signal transduction [GO:0007264] GO:0000165; GO:0005085; GO:0005096; GO:0005509; GO:0005886; GO:0007264; GO:0007265; GO:0019900; GO:0019992; GO:0031267; GO:0032045; GO:0043547; GO:0048471 25035 XM_044315140.1 0 145 0 0 0 NA NA NA NA NA NA 25036 XM_029348962.2 179 153 186 181 201 NA NA NA NA NA NA 25037 XM_044320402.1 508 278 266 434 327 NA NA NA NA NA NA 25038 XM_044318447.1 0 0 8 0 0 NA NA NA NA NA NA 25039 XM_044328857.1 0 0 14 9 1 NA NA NA NA NA NA 25040 XM_044320513.1 12 0 0 37 82 NA NA NA NA NA NA 25041 XR_006395219.1 155 33 128 361 591 NA NA NA NA NA NA 25042 XM_029357355.2 948 921 609 747 1022 D3ZQF4 1.1e-58 Inactive peptidyl-prolyl cis-trans isomerase FKBP6 (Inactive PPIase FKBP6) (36 kDa FK506-binding protein) (FK506-binding protein 6) (Immunophilin FKBP36) Rattus norvegicus (Rat) cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; meiotic cell cycle [GO:0051321]; piRNA processing [GO:0034587]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; RNA-mediated gene silencing [GO:0031047]; spermatogenesis [GO:0007283] GO:0000795; GO:0005737; GO:0005829; GO:0006457; GO:0007283; GO:0030154; GO:0031047; GO:0034587; GO:0042802; GO:0043046; GO:0045070; GO:0051321; GO:0051879 25043 XM_044323657.1 0 0 0 5 23 NA NA NA NA NA NA 25044 XM_044327883.1 56 55 47 142 82 Q05AL1 0 Armadillo repeat-containing protein 8 Danio rerio (Zebrafish) (Brachydanio rerio) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] GO:0000151; GO:0005634; GO:0005737; GO:0034657; GO:0043161 25045 XM_029354494.2 54 13 19 24 4 Q9QXW0 1.63e-51 F-box/LRR-repeat protein 6 (F-box and leucine-rich repeat protein 6) (F-box protein FBL6) Mus musculus (Mouse) entrainment of circadian clock by photoperiod [GO:0043153]; G2/M transition of mitotic cell cycle [GO:0000086]; regulation of cell cycle [GO:0051726]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0000086; GO:0005634; GO:0005829; GO:0019005; GO:0031146; GO:0043153; GO:0051726 25046 XR_006392515.1 11 0 0 0 0 NA NA NA NA NA NA 25047 XM_044309458.1 10 0 14 0 0 NA NA NA NA NA NA 25048 XM_029330955.2 1008 940 598 1060 1014 Q8JHF0 1.35e-44 Gamma-secretase subunit PEN-2 (Presenilin enhancer protein 2 homolog) Danio rerio (Zebrafish) (Brachydanio rerio) amyloid precursor protein metabolic process [GO:0042982]; amyloid-beta formation [GO:0034205]; developmental pigmentation [GO:0048066]; melanocyte migration [GO:0097324]; negative regulation of apoptotic process [GO:0043066]; negative regulation of neuron apoptotic process [GO:0043524]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219] GO:0005789; GO:0007219; GO:0007220; GO:0016020; GO:0032580; GO:0034205; GO:0042982; GO:0043066; GO:0043524; GO:0048066; GO:0070765; GO:0097324 25049 XM_044323082.1 478 1 3 3 410 NA NA NA NA NA NA 25050 XM_029327418.2 0 148 0 0 699 Q9ERS5 6.52e-28 Pleckstrin homology domain-containing family A member 2 (PH domain-containing family A member 2) (PH domain-containing adaptor PHAD47) (Tandem PH domain-containing protein 2) (TAPP-2) Mus musculus (Mouse) positive regulation of cell-matrix adhesion [GO:0001954] GO:0001954; GO:0001968; GO:0005634; GO:0005737; GO:0005886; GO:0008289; GO:0016020; GO:0030165; GO:0032991; GO:0043236; GO:0043325 25051 XM_044308683.1 50 15 11 14 24 NA NA NA NA NA NA 25052 XM_029356071.2 32 60 89 79 45 Q8NB59 1.5e-31 Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV) Homo sapiens (Human) NA GO:0005543; GO:0016020 25053 XM_044318046.1 91 90 22 39 86 NA NA NA NA NA NA 25054 XM_044308582.1 468 228 608 1 25 NA NA NA NA NA NA 25055 XM_044322102.1 2863 1899 2319 1694 1912 Q62901 1.38e-131 Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-related protein) Rattus norvegicus (Rat) branching morphogenesis of a nerve [GO:0048755]; cerebellar granule cell precursor proliferation [GO:0021930]; cerebellar Purkinje cell layer maturation [GO:0021691]; cerebellum development [GO:0021549]; chromatin remodeling [GO:0006338]; dendrite morphogenesis [GO:0048813]; DNA-templated transcription [GO:0006351]; DNA-templated transcription elongation [GO:0006354]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of DNA-templated transcription [GO:0045893]; radial glia guided migration of Purkinje cell [GO:0021942] GO:0000118; GO:0003682; GO:0003713; GO:0003714; GO:0005634; GO:0006338; GO:0006351; GO:0006354; GO:0016605; GO:0021549; GO:0021691; GO:0021930; GO:0021942; GO:0043565; GO:0045892; GO:0045893; GO:0046872; GO:0048755; GO:0048813 25056 XM_029334999.2 379 219 165 169 113 Q80VP5 2.88e-21 Mitochondrial translation release factor in rescue Mus musculus (Mouse) rescue of stalled ribosome [GO:0072344] GO:0000049; GO:0003747; GO:0005739; GO:0043023; GO:0072344 25057 XM_044309127.1 428 28 71 99 0 NA NA NA NA NA NA 25058 XM_044314271.1 0 0 0 7 0 NA NA NA NA NA NA 25059 XR_006395868.1 37 24 1 58 35 NA NA NA NA NA NA 25060 XM_044319916.1 465 233 341 344 317 Q5R478 0 AP-3 complex subunit mu-1 (AP-3 adaptor complex mu3A subunit) (Adaptor-related protein complex 3 subunit mu-1) (Mu-adaptin 3A) (Mu3A-adaptin) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192] GO:0005794; GO:0006886; GO:0008089; GO:0016192; GO:0030131; GO:0030659; GO:0031267; GO:0048490; GO:1904115 25061 XR_006394558.1 13 17 27 0 0 NA NA NA NA NA NA 25062 XM_029353480.2 329 346 259 177 231 NA NA NA NA NA NA 25063 XM_044323004.1 120 29 74 106 91 P10090 2.26e-130 Protein white (EC 7.6.2.-) (EC 7.6.2.6) (ATP-binding cassette transporter sub-family G member white) (Broad substrate specificity ATP-binding cassette transporter white) Drosophila melanogaster (Fruit fly) aminergic neurotransmitter loading into synaptic vesicle [GO:0015842]; biogenic amine biosynthetic process [GO:0042401]; cGMP transport [GO:0070731]; compound eye pigmentation [GO:0048072]; eye pigment metabolic process [GO:0042441]; eye pigment precursor transport [GO:0006856]; gravitaxis [GO:0042332]; guanine transport [GO:0015854]; histamine uptake [GO:0051615]; male courtship behavior [GO:0008049]; memory [GO:0007613]; ommochrome biosynthetic process [GO:0006727]; riboflavin transport [GO:0032218]; transmembrane transport [GO:0055085]; tryptophan transport [GO:0015827]; xanthine transport [GO:0042906] GO:0005275; GO:0005524; GO:0005886; GO:0006727; GO:0006856; GO:0007613; GO:0008049; GO:0008558; GO:0015196; GO:0015208; GO:0015827; GO:0015842; GO:0015854; GO:0016020; GO:0016887; GO:0022857; GO:0030659; GO:0031409; GO:0031410; GO:0032217; GO:0032218; GO:0042332; GO:0042401; GO:0042441; GO:0042626; GO:0042906; GO:0042907; GO:0048072; GO:0048770; GO:0051615; GO:0055085; GO:0070731; GO:0090741; GO:0098793; GO:1905948 25064 XM_029349380.2 1047 1153 618 1126 921 Q9CZ04 8.91e-68 COP9 signalosome complex subunit 7a (SGN7a) (Signalosome subunit 7a) (JAB1-containing signalosome subunit 7a) Mus musculus (Mouse) COP9 signalosome assembly [GO:0010387]; protein deneddylation [GO:0000338] GO:0000338; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0008180; GO:0010387 25065 XM_029341673.2 34 14 19 50 4 NA NA NA NA NA NA 25066 XM_044326356.1 0 0 8 29 110 NA NA NA NA NA NA 25067 XM_044323318.1 141 12 14 28 20 Q7RTR2 8.87e-37 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 25068 XM_044328740.1 85 193 100 45 192 Q96AY4 1.42e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25069 XM_044328740.1 85 193 100 45 192 Q96AY4 7.5e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25070 XM_044328740.1 85 193 100 45 192 Q96AY4 1.55e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25071 XM_044328740.1 85 193 100 45 192 Q96AY4 1.79e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25072 XM_044328740.1 85 193 100 45 192 Q96AY4 2.62e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25073 XM_044328740.1 85 193 100 45 192 Q96AY4 2.54e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25074 XM_029334085.2 295 0 0 237 215 Q09081 1.82e-144 Potassium voltage-gated channel subfamily A member 2 (KC22) (Voltage-gated potassium channel subunit Kv1.2) Oryctolagus cuniculus (Rabbit) neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233] GO:0005249; GO:0005251; GO:0005789; GO:0005886; GO:0008076; GO:0014059; GO:0019228; GO:0019233; GO:0021633; GO:0030027; GO:0030424; GO:0030425; GO:0031258; GO:0032809; GO:0033010; GO:0034765; GO:0042734; GO:0043194; GO:0043204; GO:0043679; GO:0044224; GO:0045188; GO:0051260; GO:0071805 25075 XM_044321771.1 135 254 465 534 201 NA NA NA NA NA NA 25076 XM_044327281.1 291 618 269 1141 392 NA NA NA NA NA NA 25077 XM_029339765.2 6059 8318 6251 5908 10232 O60869 4.61e-63 Endothelial differentiation-related factor 1 (EDF-1) (Multiprotein-bridging factor 1) (MBF1) Homo sapiens (Human) endothelial cell differentiation [GO:0045446]; positive regulation of DNA binding [GO:0043388]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA-templated transcription [GO:0006355]; regulation of lipid metabolic process [GO:0019216] GO:0001094; GO:0003677; GO:0003713; GO:0003723; GO:0005516; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0006355; GO:0019216; GO:0043388; GO:0045446; GO:0045893 25078 XM_029349583.2 58 0 0 0 0 Q7ZVB2 0 4-trimethylaminobutyraldehyde dehydrogenase A (TMABA-DH) (TMABADH) (EC 1.2.1.47) (Aldehyde dehydrogenase family 9 member A1-A) (EC 1.2.1.3) Danio rerio (Zebrafish) (Brachydanio rerio) carnitine biosynthetic process [GO:0045329]; cellular aldehyde metabolic process [GO:0006081]; protein homotetramerization [GO:0051289] GO:0004029; GO:0005829; GO:0006081; GO:0019145; GO:0043878; GO:0045329; GO:0047105; GO:0051289 25079 XM_029338495.2 51 0 0 0 0 P56839 0 Phosphoenolpyruvate phosphomutase (PEP mutase) (PEP phosphomutase) (Phosphoenolpyruvate mutase) (EC 5.4.2.9) Mytilus edulis (Blue mussel) organic phosphonate biosynthetic process [GO:0032923] GO:0032923; GO:0046872; GO:0050188 25080 XM_029348139.2 12 0 0 12 0 P49338 4.94e-121 Protein Wnt-4 (XWnt-4) Xenopus laevis (African clawed frog) embryonic pattern specification [GO:0009880]; glomus development [GO:0072013]; nephrostome development [GO:0039018]; pronephric nephron tubule development [GO:0039020]; Wnt signaling pathway [GO:0016055] GO:0005102; GO:0005576; GO:0009880; GO:0016055; GO:0039018; GO:0039020; GO:0072013 25081 XM_044328130.1 21 11 0 73 42 NA NA NA NA NA NA 25082 XM_044321979.1 0 0 0 0 7 Q7TS68 1.93e-134 tRNA (cytosine(72)-C(5))-methyltransferase NSUN6 (EC 2.1.1.-) (NOL1/NOP2/Sun domain family member 6) Mus musculus (Mouse) RNA methylation [GO:0001510]; tRNA C5-cytosine methylation [GO:0002946]; tRNA methylation [GO:0030488] GO:0000049; GO:0001510; GO:0002946; GO:0005654; GO:0005737; GO:0016428; GO:0030488 25083 XM_044311594.1 28 45 16 5 134 NA NA NA NA NA NA 25084 XR_006391862.1 22 9 60 71 34 NA NA NA NA NA NA 25085 XR_003824177.2 9 31 0 0 57 NA NA NA NA NA NA 25086 XM_029332964.2 1384 1092 709 1052 846 Q5R833 2.26e-37 Acyl-coenzyme A thioesterase 13 (Acyl-CoA thioesterase 13) (EC 3.1.2.-) (Hotdog-fold thioesterase superfamily member 2) (Palmitoyl-CoA hydrolase) (EC 3.1.2.2) (Thioesterase superfamily member 2) (THEM2) [Cleaved into: Acyl-coenzyme A thioesterase 13, N-terminally processed] Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) lipid metabolic process [GO:0006629] GO:0005634; GO:0005739; GO:0005819; GO:0005829; GO:0006629; GO:0016290; GO:0102991 25087 XM_029349133.2 3710 2760 2271 3709 3857 Q6PGV1 0 V-type proton ATPase subunit d 1 (V-ATPase subunit d 1) (Vacuolar proton pump subunit d 1) Danio rerio (Zebrafish) (Brachydanio rerio) cellular iron ion homeostasis [GO:0006879]; cellular response to increased oxygen levels [GO:0036295]; cilium assembly [GO:0060271]; eye pigment granule organization [GO:0008057]; heart looping [GO:0001947]; left/right axis specification [GO:0070986]; melanosome organization [GO:0032438]; neuromast hair cell development [GO:0035675]; pronephric duct development [GO:0039022]; response to copper ion [GO:0046688]; retina development in camera-type eye [GO:0060041]; retinal pigment epithelium development [GO:0003406]; vacuolar acidification [GO:0007035]; vacuolar transport [GO:0007034] GO:0001947; GO:0003406; GO:0005765; GO:0005769; GO:0006879; GO:0007034; GO:0007035; GO:0008057; GO:0016471; GO:0032438; GO:0033179; GO:0033181; GO:0035675; GO:0036295; GO:0039022; GO:0046688; GO:0046961; GO:0060041; GO:0060271; GO:0070986 25088 XM_044316373.1 273 158 169 39 82 Q96MB7 4.82e-60 Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease) Homo sapiens (Human) NA GO:0004518; GO:0005634; GO:0005829; GO:0005886; GO:0034451; GO:0046872 25089 XM_044322872.1 0 6 2 0 3 P31937 2.82e-101 3-hydroxyisobutyrate dehydrogenase, mitochondrial (HIBADH) (EC 1.1.1.31) Homo sapiens (Human) valine catabolic process [GO:0006574] GO:0005739; GO:0005759; GO:0006574; GO:0008442; GO:0016616; GO:0050661; GO:0051287 25090 XM_044323326.1 13 0 0 0 0 NA NA NA NA NA NA 25091 XM_029335881.2 102 207 111 221 145 NA NA NA NA NA NA 25092 XM_044323523.1 41 12 28 40 28 Q9CQ24 9.3e-27 F-box only protein 36 Mus musculus (Mouse) NA NA 25093 XM_044320407.1 219 280 190 201 182 NA NA NA NA NA NA 25094 XR_006397309.1 4 8 11 3 11 NA NA NA NA NA NA 25095 XM_044309591.1 12 8 29 5 63 NA NA NA NA NA NA 25096 XM_044315710.1 0 0 197 0 363 NA NA NA NA NA NA 25097 XM_044313743.1 4 17 7 11 8 Q9MYW9 2.02e-21 Mu-type opioid receptor (M-OR-1) (MOR-1) Macaca mulatta (Rhesus macaque) adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway [GO:0007197]; G protein-coupled opioid receptor signaling pathway [GO:0038003]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of Wnt protein secretion [GO:0061358]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neurogenesis [GO:0050769]; regulation of NMDA receptor activity [GO:2000310]; sensory perception of pain [GO:0019233] GO:0001965; GO:0004930; GO:0004979; GO:0005245; GO:0005768; GO:0005886; GO:0007197; GO:0007200; GO:0007218; GO:0019233; GO:0030424; GO:0030425; GO:0031681; GO:0038003; GO:0038047; GO:0042277; GO:0042923; GO:0043005; GO:0043204; GO:0043951; GO:0045019; GO:0045202; GO:0050769; GO:0051481; GO:0061358; GO:0070374; GO:2000310 25098 XM_029349743.2 275 165 188 267 216 Q5BKL9 3.64e-56 45 kDa calcium-binding protein (Cab45) (Stromal cell-derived factor 4) (SDF-4) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005509; GO:0005796 25099 XR_006397944.1 330 159 221 315 293 Q6VVW5 0 Atrial natriuretic peptide receptor 2 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type B) (ANP-B) (ANPR-B) (NPR-B) (Guanylate cyclase B) (GC-B) Mus musculus (Mouse) activation of meiosis involved in egg activation [GO:0060466]; axonogenesis [GO:0007409]; axonogenesis involved in innervation [GO:0060385]; blood circulation [GO:0008015]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; bone development [GO:0060348]; bone growth [GO:0098868]; c-di-GMP signaling [GO:0061939]; cartilage development [GO:0051216]; cellular response to cGMP [GO:0071321]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to peptide [GO:1901653]; cGMP biosynthetic process [GO:0006182]; cGMP metabolic process [GO:0046068]; cGMP-mediated signaling [GO:0019934]; chemical synaptic transmission [GO:0007268]; chondrocyte differentiation [GO:0002062]; chondrocyte proliferation [GO:0035988]; chromosome organization [GO:0051276]; collateral sprouting [GO:0048668]; cumulus cell differentiation [GO:0001549]; digestive tract development [GO:0048565]; digestive tract morphogenesis [GO:0048546]; endochondral ossification [GO:0001958]; epidermal growth factor receptor signaling pathway [GO:0007173]; execution phase of apoptosis [GO:0097194]; female genitalia development [GO:0030540]; gastric emptying [GO:0035483]; genitalia morphogenesis [GO:0035112]; germ cell development [GO:0007281]; growth plate cartilage development [GO:0003417]; limb development [GO:0060173]; limb morphogenesis [GO:0035108]; lymph vessel development [GO:0001945]; MAPK cascade [GO:0000165]; meiotic cell cycle [GO:0051321]; meiotic cell cycle process involved in oocyte maturation [GO:1903537]; multicellular organism growth [GO:0035264]; multicellular organism reproduction [GO:0032504]; negative regulation of meiotic cell cycle [GO:0051447]; negative regulation of oocyte maturation [GO:1900194]; nerve development [GO:0021675]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; oocyte development [GO:0048599]; ovarian follicle development [GO:0001541]; positive regulation of cGMP-mediated signaling [GO:0010753]; post-anal tail morphogenesis [GO:0036342]; protein phosphorylation [GO:0006468]; receptor guanylyl cyclase signaling pathway [GO:0007168]; reproductive process [GO:0022414]; response to fibroblast growth factor [GO:0071774]; response to hormone [GO:0009725]; response to luteinizing hormone [GO:0034699]; response to salt [GO:1902074]; response to wounding [GO:0009611]; sensory perception of sound [GO:0007605]; signal transduction [GO:0007165]; single fertilization [GO:0007338]; smooth muscle tissue development [GO:0048745]; spermatogenesis [GO:0007283]; startle response [GO:0001964]; vacuole organization [GO:0007033]; vascular wound healing [GO:0061042]; vasculogenesis [GO:0001570]; vestibulocochlear nerve development [GO:0021562]; vestibulocochlear nerve maturation [GO:0021647]; white fat cell differentiation [GO:0050872] GO:0000165; GO:0001541; GO:0001549; GO:0001568; GO:0001570; GO:0001653; GO:0001945; GO:0001958; GO:0001964; GO:0001974; GO:0002062; GO:0003417; GO:0004383; GO:0004672; GO:0005524; GO:0005525; GO:0005634; GO:0005737; GO:0005886; GO:0005929; GO:0006182; GO:0006468; GO:0007033; GO:0007165; GO:0007168; GO:0007173; GO:0007268; GO:0007281; GO:0007283; GO:0007338; GO:0007409; GO:0007605; GO:0008015; GO:0009611; GO:0009725; GO:0010753; GO:0016941; GO:0017046; GO:0019228; GO:0019934; GO:0021562; GO:0021647; GO:0021675; GO:0022414; GO:0030540; GO:0032504; GO:0034699; GO:0035108; GO:0035112; GO:0035264; GO:0035483; GO:0035988; GO:0036342; GO:0042562; GO:0042802; GO:0043005; GO:0045202; GO:0046068; GO:0048546; GO:0048565; GO:0048599; GO:0048668; GO:0048745; GO:0050872; GO:0051216; GO:0051276; GO:0051321; GO:0051402; GO:0051447; GO:0060173; GO:0060348; GO:0060385; GO:0060466; GO:0061042; GO:0061939; GO:0071321; GO:0071774; GO:0097011; GO:0097194; GO:0098868; GO:1900194; GO:1901653; GO:1902074; GO:1903537 25100 XR_006397411.1 0 0 0 0 16 NA NA NA NA NA NA 25101 XM_044325901.1 0 11 12 6 11 NA NA NA NA NA NA 25102 XM_029358143.2 120 135 133 72 100 NA NA NA NA NA NA 25103 XM_044318748.1 807 111 534 902 2542 NA NA NA NA NA NA 25104 XR_006396883.1 4 9 9 2 21 NA NA NA NA NA NA 25105 XM_044320983.1 14 0 16 5 51 Q9VBW3 4.06e-61 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 25106 XR_006394529.1 14 0 0 0 3 NA NA NA NA NA NA 25107 XR_003825325.2 0 9 5 25 3 NA NA NA NA NA NA 25108 XM_044322821.1 7607 5340 3412 4381 2288 O61491 0 Flotillin-1 Drosophila melanogaster (Fruit fly) positive regulation of cell junction assembly [GO:1901890]; positive regulation of cell-cell adhesion mediated by cadherin [GO:2000049]; positive regulation of endocytosis [GO:0045807]; protein kinase C signaling [GO:0070528]; protein localization to plasma membrane [GO:0072659]; regulation of receptor internalization [GO:0002090] GO:0002090; GO:0005198; GO:0005737; GO:0005886; GO:0016600; GO:0031410; GO:0045807; GO:0070528; GO:0072659; GO:1901890; GO:2000049 25109 XM_029346336.2 55 132 0 21 16 Q9C040 9.54e-124 Tripartite motif-containing protein 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRIM2) (RING finger protein 86) (RING-type E3 ubiquitin transferase TRIM2) Homo sapiens (Human) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; regulation of neuron apoptotic process [GO:0043523] GO:0000209; GO:0004842; GO:0005737; GO:0008270; GO:0043161; GO:0043523; GO:0061630 25110 XM_029346336.2 55 132 0 21 16 Q9C040 2.03e-22 Tripartite motif-containing protein 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRIM2) (RING finger protein 86) (RING-type E3 ubiquitin transferase TRIM2) Homo sapiens (Human) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; regulation of neuron apoptotic process [GO:0043523] GO:0000209; GO:0004842; GO:0005737; GO:0008270; GO:0043161; GO:0043523; GO:0061630 25111 XM_029327854.2 0 2 12 2 0 NA NA NA NA NA NA 25112 XM_029329704.2 834 471 295 811 961 Q6GQN0 1.5e-77 Centrosomal protein of 41 kDa (Cep41) (Testis-specific gene A14 protein) Danio rerio (Zebrafish) (Brachydanio rerio) axoneme assembly [GO:0035082]; cilium assembly [GO:0060271]; neural crest cell migration [GO:0001755]; protein polyglutamylation [GO:0018095]; protein transport [GO:0015031] GO:0001755; GO:0005737; GO:0005814; GO:0005929; GO:0015031; GO:0018095; GO:0035082; GO:0036064; GO:0060271; GO:0070740 25113 XR_003825319.2 150 258 134 141 194 NA NA NA NA NA NA 25114 XM_029331713.2 18608 13399 14240 20633 5477 P19615 5.01e-73 Major yolk protein (MYP) (Vitellogenin) Strongylocentrotus purpuratus (Purple sea urchin) iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826] GO:0005615; GO:0005769; GO:0005886; GO:0006826; GO:0045735; GO:0046872; GO:0055037; GO:0055072 25115 XM_029339110.2 2651 1927 1736 2309 684 Q3TZ87 1.2e-22 E3 ubiquitin-protein ligase MARCHF9 (EC 2.3.2.27) (Membrane-associated RING finger protein 9) (Membrane-associated RING-CH protein IX) (MARCH-IX) (RING-type E3 ubiquitin transferase MARCHF9) Mus musculus (Mouse) NA GO:0000139; GO:0004842; GO:0005765; GO:0005795; GO:0005802; GO:0008270 25116 XM_029328169.2 14 1 0 0 11 NA NA NA NA NA NA 25117 XM_044312641.1 2 0 6 6 2 NA NA NA NA NA NA 25118 XM_029333348.2 0 0 3 6 15 NA NA NA NA NA NA 25119 XM_044324798.1 39 204 100 6 141 NA NA NA NA NA NA 25120 XM_044319323.1 47 7 19 41 92 Q708S7 5.06e-46 Acid-sensing ion channel 1A (ASIC1-A) (Acid-sensing ion channel 1.2-A) (Amiloride-sensitive cation channel 2-B, neuronal-A) (ZASIC1.2) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to pH [GO:0071467]; protein homotrimerization [GO:0070207]; sodium ion transmembrane transport [GO:0035725] GO:0005261; GO:0005886; GO:0015280; GO:0035725; GO:0044736; GO:0070207; GO:0071467 25121 XM_029340430.2 0 9 11 23 44 NA NA NA NA NA NA 25122 XR_006397062.1 76 41 31 58 94 NA NA NA NA NA NA 25123 XM_044307937.1 39 0 31 85 261 NA NA NA NA NA NA 25124 XM_044328913.1 0 6 6 9 11 Q80XJ3 4.28e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 25125 XM_044328913.1 0 6 6 9 11 Q80XJ3 6.11e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 25126 XM_044328913.1 0 6 6 9 11 Q80XJ3 2.07e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 25127 XM_044328913.1 0 6 6 9 11 Q80XJ3 2.95e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 25128 XM_044328913.1 0 6 6 9 11 Q80XJ3 4e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 25129 XM_044328913.1 0 6 6 9 11 Q80XJ3 4.44e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 25130 XM_044328913.1 0 6 6 9 11 Q80XJ3 8.31e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 25131 XM_044328913.1 0 6 6 9 11 Q80XJ3 3.39e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 25132 XM_044328913.1 0 6 6 9 11 Q80XJ3 8.47e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 25133 XM_044328913.1 0 6 6 9 11 Q80XJ3 1.18e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 25134 XM_044328913.1 0 6 6 9 11 Q80XJ3 8.4e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 25135 XM_044328913.1 0 6 6 9 11 Q80XJ3 2.35e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 25136 XM_044328913.1 0 6 6 9 11 Q80XJ3 4.07e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 25137 XM_044328913.1 0 6 6 9 11 Q80XJ3 4.99e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 25138 XR_006391801.1 11 31 25 77 19 NA NA NA NA NA NA 25139 XM_029345639.2 40 17 72 9 84 NA NA NA NA NA NA 25140 XM_044324011.1 9 0 0 0 0 NA NA NA NA NA NA 25141 XM_044325255.1 41 64 36 39 178 P42262 3.3e-83 Glutamate receptor 2 (GluR-2) (AMPA-selective glutamate receptor 2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (GluA2) Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; signal transduction [GO:0007165]; synaptic transmission, glutamatergic [GO:0035249] GO:0001540; GO:0004970; GO:0004971; GO:0005789; GO:0005886; GO:0007165; GO:0007268; GO:0009897; GO:0014069; GO:0015276; GO:0030425; GO:0030666; GO:0032279; GO:0032281; GO:0035235; GO:0035249; GO:0038023; GO:0043025; GO:0043197; GO:0060076; GO:0098794; GO:0098839; GO:0098843 25142 XM_029356901.2 965 1230 820 1346 1305 Q3U7U3 1.99e-54 F-box only protein 7 Mus musculus (Mouse) autophagy of mitochondrion [GO:0000422]; lymphocyte differentiation [GO:0030098]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of lymphocyte differentiation [GO:0045620]; negative regulation of neuron death [GO:1901215]; negative regulation of oxidative stress-induced neuron death [GO:1903204]; positive regulation of autophagy of mitochondrion [GO:1903599]; protein targeting to mitochondrion [GO:0006626]; protein ubiquitination [GO:0016567]; regulation of locomotion [GO:0040012]; regulation of neuron projection development [GO:0010975]; regulation of protein stability [GO:0031647]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000151; GO:0000422; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005829; GO:0006511; GO:0006626; GO:0010975; GO:0016567; GO:0019005; GO:0019901; GO:0030098; GO:0031625; GO:0031647; GO:0032991; GO:0040012; GO:0043130; GO:0045620; GO:0045736; GO:0046982; GO:0097409; GO:0097414; GO:0097462; GO:1901215; GO:1903204; GO:1903208; GO:1903599; GO:1990037; GO:1990038; GO:1990756; GO:2000134 25143 XM_044316509.1 62 55 43 42 45 NA NA NA NA NA NA 25144 XR_006392004.1 0 1 2 0 6 NA NA NA NA NA NA 25145 XM_044317022.1 2 0 0 0 34 P54131 4.92e-102 Neuronal acetylcholine receptor subunit alpha-7 Bos taurus (Bovine) calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; cognition [GO:0050890]; ion transmembrane transport [GO:0034220]; negative regulation of tumor necrosis factor production [GO:0032720]; nervous system process [GO:0050877]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAPK cascade [GO:0043410]; regulation of membrane potential [GO:0042391]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271] GO:0001540; GO:0001666; GO:0005231; GO:0005886; GO:0005892; GO:0006816; GO:0006874; GO:0007165; GO:0007268; GO:0007271; GO:0008284; GO:0015464; GO:0015643; GO:0017081; GO:0022848; GO:0030594; GO:0032720; GO:0034220; GO:0035094; GO:0042166; GO:0042391; GO:0042803; GO:0043005; GO:0043410; GO:0045202; GO:0045211; GO:0045766; GO:0050877; GO:0050890; GO:1904315 25146 XM_044313756.1 3 13 0 0 11 NA NA NA NA NA NA 25147 XM_044327003.1 64 270 363 198 178 NA NA NA NA NA NA 25148 XM_029352052.2 39 4 190 0 30 Q4V7Q8 8.8e-21 Transmembrane protein 220 Xenopus laevis (African clawed frog) NA GO:0016020 25149 XM_044315320.1 587 0 341 418 281 NA NA NA NA NA NA 25150 XM_029347285.2 113 105 89 87 202 NA NA NA NA NA NA 25151 XM_044307942.1 169 11 44 0 0 NA NA NA NA NA NA 25152 XR_003824484.2 7 49 85 0 81 NA NA NA NA NA NA 25153 XM_044318353.1 33 11 8 49 68 NA NA NA NA NA NA 25154 XM_044307924.1 18 0 15 0 56 NA NA NA NA NA NA 25155 XM_029339320.2 2726 2036 1082 2393 2276 O97341 1.84e-35 Calmodulin (CaM) Suberites domuncula (Sponge) NA GO:0005509 25156 XR_003826744.2 70 26 39 75 79 NA NA NA NA NA NA 25157 XM_029353010.2 505 314 120 362 416 Q8VIJ6 9.52e-86 Splicing factor, proline- and glutamine-rich (DNA-binding p52/p100 complex, 100 kDa subunit) (Polypyrimidine tract-binding protein-associated-splicing factor) (PSF) (PTB-associated-splicing factor) Mus musculus (Mouse) activation of innate immune response [GO:0002218]; alternative mRNA splicing, via spliceosome [GO:0000380]; cellular response to DNA damage stimulus [GO:0006974]; chromosome organization [GO:0051276]; dendritic transport of messenger ribonucleoprotein complex [GO:0098963]; double-strand break repair via homologous recombination [GO:0000724]; histone H3 deacetylation [GO:0070932]; innate immune response [GO:0045087]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of sister chromatid cohesion [GO:0045876]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell cycle [GO:0051726]; regulation of circadian rhythm [GO:0042752]; regulation of DNA-templated transcription [GO:0006355]; rhythmic process [GO:0048511] GO:0000122; GO:0000380; GO:0000724; GO:0000785; GO:0000976; GO:0002218; GO:0003677; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0006355; GO:0006974; GO:0016363; GO:0016607; GO:0032839; GO:0042382; GO:0042752; GO:0042754; GO:0042803; GO:0042826; GO:0045087; GO:0045876; GO:0045892; GO:0045944; GO:0048511; GO:0051276; GO:0051726; GO:0070932; GO:0090575; GO:0098963; GO:1902177 25158 XR_006392373.1 7 0 0 0 1 NA NA NA NA NA NA 25159 XM_044323465.1 3 12 0 0 0 NA NA NA NA NA NA 25160 XM_029347878.2 1177 611 170 418 477 Q5RET6 4.84e-152 Transmembrane protein 184C (Transmembrane protein 34) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0016020 25161 XM_044323142.1 7 1 4 11 40 NA NA NA NA NA NA 25162 XM_029342414.2 273 36 0 0 0 P16157 8.52e-95 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 25163 XM_029342414.2 273 36 0 0 0 P16157 5.33e-89 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 25164 XM_044318227.1 0 0 0 44 27 NA NA NA NA NA NA 25165 XM_029331213.2 3653 2765 2102 3336 3072 Q862Z5 2.22e-28 Cystatin-B (Stefin-B) Macaca fuscata fuscata (Japanese macaque) negative regulation of peptidase activity [GO:0010466] GO:0004869; GO:0005634; GO:0005737; GO:0010466 25166 XM_044312029.1 17 6 17 131 11 NA NA NA NA NA NA 25167 XM_029350981.2 0 28 17 31 12 Q8IZU8 0 Dermatan-sulfate epimerase-like protein (EC 5.1.-.-) Homo sapiens (Human) chondroitin sulfate metabolic process [GO:0030204]; dermatan sulfate biosynthetic process [GO:0030208]; dermatan sulfate metabolic process [GO:0030205] GO:0000139; GO:0008146; GO:0030204; GO:0030205; GO:0030208; GO:0047757 25168 XM_044324118.1 2 18 6 7 5 NA NA NA NA NA NA 25169 XM_029336819.2 454 957 252 210 1433 Q5VVW2 0 GTPase-activating Rap/Ran-GAP domain-like protein 3 Homo sapiens (Human) activation of GTPase activity [GO:0090630]; regulation of small GTPase mediated signal transduction [GO:0051056] GO:0005096; GO:0005737; GO:0051056; GO:0090630 25170 XM_029324682.2 133 0 0 0 0 Q9Y2U5 2.23e-139 Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2) Homo sapiens (Human) cellular response to mechanical stimulus [GO:0071260]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468] GO:0004672; GO:0004674; GO:0004709; GO:0005524; GO:0005654; GO:0005737; GO:0005829; GO:0006468; GO:0019901; GO:0035556; GO:0046872; GO:0071260; GO:0106310 25171 XM_029355094.2 738 580 420 652 742 O08654 0 Phagosome assembly factor 1 Rattus norvegicus (Rat) Golgi to plasma membrane protein transport [GO:0043001] GO:0000407; GO:0005802; GO:0016020; GO:0030165; GO:0030425; GO:0030672; GO:0035254; GO:0043001 25172 XM_029339366.2 13 299 334 768 72 Q9Z206 4.74e-118 Neuroepithelial cell-transforming gene 1 protein (Rho guanine nucleotide exchange factor 8) Mus musculus (Mouse) cellular response to hydrogen peroxide [GO:0070301]; cellular response to ionizing radiation [GO:0071479]; intracellular signal transduction [GO:0035556]; myoblast migration [GO:0051451]; positive regulation of apoptotic process [GO:0043065]; positive regulation of GTPase activity [GO:0043547]; positive regulation of Rho protein signal transduction [GO:0035025] GO:0005085; GO:0005634; GO:0005737; GO:0035025; GO:0035556; GO:0043065; GO:0043547; GO:0051451; GO:0070301; GO:0071479 25173 XM_044309968.1 55 4 96 5 15 NA NA NA NA NA NA 25174 XM_029324608.2 44 63 0 0 3 NA NA NA NA NA NA 25175 XR_006392953.1 41 2 25 5 151 NA NA NA NA NA NA 25176 XM_044317961.1 7 0 0 51 0 NA NA NA NA NA NA 25177 XR_006394666.1 88 22 22 26 84 Q08832 6.86e-59 Gamma-aminobutyric acid receptor subunit beta-like (GABA(A) receptor) Drosophila melanogaster (Fruit fly) chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165] GO:0004890; GO:0005231; GO:0005886; GO:0007165; GO:0007268; GO:0022851; GO:0030594; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:1902476; GO:1902711; GO:1904315 25178 XR_006394666.1 88 22 22 26 84 Q08832 6.86e-59 Gamma-aminobutyric acid receptor subunit beta-like (GABA(A) receptor) Drosophila melanogaster (Fruit fly) chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165] GO:0004890; GO:0005231; GO:0005886; GO:0007165; GO:0007268; GO:0022851; GO:0030594; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:1902476; GO:1902711; GO:1904315 25179 XM_044319450.1 162 80 105 156 147 P23819 1.31e-87 Glutamate receptor 2 (GluR-2) (AMPA-selective glutamate receptor 2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (GluA2) Mus musculus (Mouse) cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to glycine [GO:1905430]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966] GO:0000149; GO:0001540; GO:0001919; GO:0004970; GO:0004971; GO:0005234; GO:0005783; GO:0005789; GO:0005886; GO:0007268; GO:0008021; GO:0008092; GO:0009986; GO:0014069; GO:0015276; GO:0015277; GO:0016020; GO:0019865; GO:0019901; GO:0030165; GO:0030424; GO:0030425; GO:0030426; GO:0030672; GO:0031623; GO:0032279; GO:0032281; GO:0032590; GO:0032839; GO:0032991; GO:0035235; GO:0035254; GO:0035255; GO:0036477; GO:0038023; GO:0042734; GO:0042802; GO:0043005; GO:0043025; GO:0043195; GO:0043197; GO:0043198; GO:0043204; GO:0044326; GO:0044327; GO:0044877; GO:0045184; GO:0045202; GO:0045211; GO:0048787; GO:0050806; GO:0051117; GO:0051262; GO:0051966; GO:0097060; GO:0097110; GO:0098685; GO:0098793; GO:0098839; GO:0098978; GO:0099507; GO:0099544; GO:0106033; GO:1904315; GO:1905430; GO:1990416 25180 XM_044319740.1 638 55 491 222 741 NA NA NA NA NA NA 25181 XM_044306803.1 148 0 15 198 0 O15033 0 Apoptosis-resistant E3 ubiquitin protein ligase 1 (EC 2.3.2.26) (Apoptosis-resistant HECT-type E3 ubiquitin transferase 1) Homo sapiens (Human) apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K11-linked ubiquitination [GO:0070979]; protein K33-linked ubiquitination [GO:1990390]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of inflammatory response [GO:0050727]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000209; GO:0004842; GO:0005737; GO:0005829; GO:0006511; GO:0006915; GO:0016567; GO:0043066; GO:0043161; GO:0050727; GO:0061630; GO:0070979; GO:1990390 25182 XM_044314831.1 26 5 6 0 5 NA NA NA NA NA NA 25183 XM_029327015.2 0 0 0 0 6 P54318 1.07e-46 Pancreatic lipase-related protein 2 (PL-RP2) (Cytotoxic T lymphocyte lipase) (Galactolipase) (EC 3.1.1.26) (Secretory glycoprotein GP-3) (Triacylglycerol lipase) (EC 3.1.1.3) Rattus norvegicus (Rat) cellular defense response [GO:0006968]; galactolipid catabolic process [GO:0019376]; intestinal lipid catabolic process [GO:0044258]; lipid catabolic process [GO:0016042]; phosphatidylcholine catabolic process [GO:0034638]; phospholipid catabolic process [GO:0009395]; phospholipid metabolic process [GO:0006644]; post-embryonic development [GO:0009791]; response to bacterium [GO:0009617]; response to food [GO:0032094]; response to glucocorticoid [GO:0051384]; response to lipid [GO:0033993]; response to peptide hormone [GO:0043434]; triglyceride catabolic process [GO:0019433] GO:0004620; GO:0004806; GO:0005509; GO:0005615; GO:0006644; GO:0006968; GO:0009395; GO:0009617; GO:0009791; GO:0016042; GO:0016298; GO:0019376; GO:0019433; GO:0032094; GO:0033993; GO:0034638; GO:0042589; GO:0043005; GO:0043434; GO:0044258; GO:0047372; GO:0047714; GO:0051384; GO:0102549 25184 XR_006391959.1 6 0 37 24 3 NA NA NA NA NA NA 25185 XM_044315076.1 0 9 0 0 0 P0CT39 2.78e-72 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 25186 XM_044312830.1 38 39 44 41 73 NA NA NA NA NA NA 25187 XM_044311845.1 1039 560 766 1194 701 F8J2D3 2e-177 Phospholipase-B 81 (PLB) (EC 3.1.1.-) Drysdalia coronoides (White-lipped snake) (Hoplocephalus coronoides) hemolysis in another organism [GO:0044179]; lipid catabolic process [GO:0016042] GO:0004620; GO:0005576; GO:0016042; GO:0044179; GO:0090729 25188 XM_044310604.1 2407 944 840 1216 1645 Q08D62 3.34e-45 Protein maelstrom homolog Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; meiotic cell cycle [GO:0051321]; piRNA processing [GO:0034587]; regulation of miRNA-mediated gene silencing [GO:0060964]; RNA-mediated gene silencing [GO:0031047]; spermatogenesis [GO:0007283] GO:0003677; GO:0005634; GO:0005737; GO:0007283; GO:0030154; GO:0031047; GO:0034587; GO:0043046; GO:0043186; GO:0051321; GO:0060964; GO:0071547 25189 XM_029330709.2 0 0 0 44 0 A1L3F5 1.43e-103 C-Maf-inducing protein (c-Mip) Xenopus laevis (African clawed frog) NA GO:0005634; GO:0005737 25190 XM_029330709.2 0 0 0 44 0 A1L3F5 6.99e-88 C-Maf-inducing protein (c-Mip) Xenopus laevis (African clawed frog) NA GO:0005634; GO:0005737 25191 XM_044322145.1 12 154 82 305 545 A7T1N0 0 Transient receptor potential cation channel subfamily M member-like 2 (nvTRPM2) Nematostella vectensis (Starlet sea anemone) calcium ion transmembrane transport [GO:0070588]; cation transmembrane transport [GO:0098655]; sodium ion transmembrane transport [GO:0035725] GO:0005261; GO:0005886; GO:0015280; GO:0035725; GO:0046872; GO:0047631; GO:0070588; GO:0098655; GO:0099604 25192 XM_029344602.2 0 0 0 187 53 NA NA NA NA NA NA 25193 XM_029332982.2 21 0 16 32 0 Q92667 3.2e-38 A-kinase anchor protein 1, mitochondrial (A-kinase anchor protein 149 kDa) (AKAP 149) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Protein kinase A-anchoring protein 1) (PRKA1) (Spermatid A-kinase anchor protein 84) (S-AKAP84) Homo sapiens (Human) antiviral innate immune response [GO:0140374]; apoptotic process [GO:0006915] GO:0003723; GO:0005739; GO:0005741; GO:0005829; GO:0006915; GO:0016020; GO:0034237; GO:0140374 25194 XR_006391482.1 145 367 44 69 104 NA NA NA NA NA NA 25195 XM_029335320.2 0 0 42 80 0 E2RDZ6 6.8e-119 NAD-dependent protein deacylase sirtuin-5, mitochondrial (EC 2.3.1.-) (Regulatory protein SIR2 homolog 5) (SIR2-like protein 5) Canis lupus familiaris (Dog) (Canis familiaris) peptidyl-lysine demalonylation [GO:0036047]; peptidyl-lysine desuccinylation [GO:0036049]; protein deacetylation [GO:0006476]; protein deglutarylation [GO:0061698]; protein demalonylation [GO:0036046]; protein desuccinylation [GO:0036048]; regulation of ketone biosynthetic process [GO:0010566] GO:0005634; GO:0005739; GO:0005829; GO:0006476; GO:0008270; GO:0010566; GO:0016740; GO:0034979; GO:0036046; GO:0036047; GO:0036048; GO:0036049; GO:0036054; GO:0036055; GO:0061697; GO:0061698; GO:0070403 25196 XM_044309034.1 1539 668 1315 604 1004 A4IIK1 8.19e-54 Malignant fibrous histiocytoma-amplified sequence 1 homolog Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) inflammatory response [GO:0006954]; innate immune response [GO:0045087]; regulation of signal transduction [GO:0009966] GO:0005525; GO:0005737; GO:0006954; GO:0009966; GO:0045087 25197 XM_044307497.1 2071 2833 996 1552 1471 O43581 6.84e-22 Synaptotagmin-7 (IPCA-7) (Prostate cancer-associated protein 7) (Synaptotagmin VII) (SytVII) Homo sapiens (Human) calcium ion regulated lysosome exocytosis [GO:1990927]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; phagocytosis [GO:0006909]; phagosome-lysosome fusion [GO:0090385]; plasma membrane repair [GO:0001778]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; regulation of bone remodeling [GO:0046850]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of glucagon secretion [GO:0070092]; regulation of insulin secretion [GO:0050796]; regulation of phagocytosis [GO:0050764]; regulation of synaptic vesicle endocytosis [GO:1900242]; short-term synaptic potentiation [GO:1990926]; synaptic vesicle recycling [GO:0036465]; vesicle-mediated cholesterol transport [GO:0090119]; vesicle-mediated transport [GO:0016192] GO:0000149; GO:0001778; GO:0001786; GO:0005509; GO:0005516; GO:0005544; GO:0005546; GO:0005764; GO:0005765; GO:0005777; GO:0005778; GO:0005829; GO:0005886; GO:0006909; GO:0008021; GO:0014059; GO:0016192; GO:0017156; GO:0017158; GO:0019905; GO:0030276; GO:0030670; GO:0030672; GO:0031045; GO:0032009; GO:0036465; GO:0042734; GO:0042995; GO:0045956; GO:0046850; GO:0048791; GO:0050764; GO:0050796; GO:0070062; GO:0070092; GO:0070382; GO:0071277; GO:0090119; GO:0090385; GO:0098686; GO:1900242; GO:1990926; GO:1990927 25198 XM_044310793.1 36 0 53 27 33 NA NA NA NA NA NA 25199 XM_044318330.1 0 0 0 0 6 NA NA NA NA NA NA 25200 XM_044315906.1 10 19 29 25 30 NA NA NA NA NA NA 25201 XM_029354661.2 478 82 331 134 1063 NA NA NA NA NA NA 25202 XM_044318152.1 56 28 14 31 33 Q8BZQ2 9.33e-27 Cysteine-rich secretory protein LCCL domain-containing 2 (Coffeecrisp) Mus musculus (Mouse) extracellular matrix organization [GO:0030198]; face morphogenesis [GO:0060325]; lung development [GO:0030324] GO:0005539; GO:0005615; GO:0008201; GO:0030133; GO:0030198; GO:0030324; GO:0031012; GO:0060325 25203 XM_044307494.1 1746 1900 1470 1792 1826 NA NA NA NA NA NA 25204 XM_029343799.2 2267 2107 1544 1566 2340 Q5PQ71 3.51e-70 Isochorismatase domain-containing protein 2 Xenopus laevis (African clawed frog) NA NA 25205 XR_003825914.2 107 54 71 181 234 NA NA NA NA NA NA 25206 XM_029357627.2 0 6 5 11 7 Q8BJS4 1.27e-52 SUN domain-containing protein 2 (Protein unc-84 homolog B) (Sad1/unc-84 protein-like 2) Mus musculus (Mouse) centrosome localization [GO:0051642]; meiotic cell cycle [GO:0051321]; nuclear envelope organization [GO:0006998]; nuclear matrix anchoring at nuclear membrane [GO:0090292]; nuclear migration along microfilament [GO:0031022]; nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration [GO:0021817]; positive regulation of cell migration [GO:0030335] GO:0000781; GO:0000794; GO:0005521; GO:0005635; GO:0005637; GO:0006998; GO:0010008; GO:0021817; GO:0030335; GO:0031022; GO:0031965; GO:0034993; GO:0042802; GO:0043495; GO:0051321; GO:0051642; GO:0090292; GO:0140444 25207 XM_029349407.2 6 0 0 70 40 NA NA NA NA NA NA 25208 XM_029324151.2 37 124 101 123 197 NA NA NA NA NA NA 25209 XM_044311298.1 0 15 0 0 0 NA NA NA NA NA NA 25210 XM_044327123.1 69 95 26 73 49 NA NA NA NA NA NA 25211 XM_029329825.2 0 0 0 0 694 Q9Y5B8 1.18e-137 Nucleoside diphosphate kinase 7 (NDK 7) (NDP kinase 7) (EC 2.7.4.6) (nm23-H7) Homo sapiens (Human) CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside diphosphate phosphorylation [GO:0006165]; UTP biosynthetic process [GO:0006228] GO:0004550; GO:0005524; GO:0005813; GO:0005829; GO:0005879; GO:0006165; GO:0006183; GO:0006228; GO:0006241; GO:0046872 25212 XM_044314248.1 0 0 0 19 29 NA NA NA NA NA NA 25213 XM_044329168.1 5407 2837 2248 5888 4762 A2AHL1 6.44e-162 Anoctamin-3 (Transmembrane protein 16C) Mus musculus (Mouse) calcium activated galactosylceramide scrambling [GO:0061591]; calcium activated phosphatidylcholine scrambling [GO:0061590]; chloride transmembrane transport [GO:1902476]; detection of mechanical stimulus [GO:0050982]; detection of temperature stimulus [GO:0016048]; establishment of localization in cell [GO:0051649]; transmembrane transport [GO:0055085] GO:0005254; GO:0005886; GO:0016048; GO:0017128; GO:0046983; GO:0050982; GO:0051649; GO:0055085; GO:0061590; GO:0061591; GO:1902476 25214 XM_029333272.2 453 67 34 206 221 NA NA NA NA NA NA 25215 XR_003823219.2 17 12 8 51 17 NA NA NA NA NA NA 25216 XM_029329894.2 15 19 19 24 50 Q94515 3.21e-129 Sphingolipid delta(4)-desaturase DES1 (EC 1.14.19.17) (Degenerative spermatocyte homolog 1) (DES-1) (Dihydroceramide desaturase-1) Drosophila melanogaster (Fruit fly) ceramide biosynthetic process [GO:0046513]; negative regulation of lipophagy [GO:1904503]; spermatogenesis [GO:0007283]; spindle assembly involved in male meiosis [GO:0007053] GO:0005739; GO:0005770; GO:0005783; GO:0005789; GO:0005886; GO:0007053; GO:0007283; GO:0016006; GO:0042284; GO:0046513; GO:0070938; GO:1904503 25217 XM_044319032.1 0 0 2 0 35 NA NA NA NA NA NA 25218 XM_029333443.2 54 24 25 0 30 NA NA NA NA NA NA 25219 XM_029327326.2 43 0 44 56 73 Q5JL96 5.7e-30 Probable E3 ubiquitin-protein ligase RZFP34 (EC 2.3.2.27) (OsRFP1) (RING zinc-finger protein 34) (OsRZFP34) Oryza sativa subsp. japonica (Rice) protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0005634; GO:0006511; GO:0008270; GO:0016567; GO:0061630 25220 XM_029331356.2 0 0 6 0 0 Q09575 2.8e-43 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 25221 XM_029341125.2 2684 2915 1977 2136 1679 Q99LW6 2.47e-23 YY1-associated factor 2 Mus musculus (Mouse) negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA-templated transcription [GO:0006355] GO:0003677; GO:0003712; GO:0003713; GO:0003714; GO:0005634; GO:0005654; GO:0005829; GO:0006355; GO:0045892; GO:0045893; GO:0046872 25222 XM_029346382.2 32 6 106 7 234 D3YXG0 3.29e-66 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 25223 XM_029346382.2 32 6 106 7 234 D3YXG0 2.2e-50 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 25224 XM_029346382.2 32 6 106 7 234 D3YXG0 9.69e-34 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 25225 XM_044321835.1 37 52 42 52 299 Q9XTR8 6.24e-37 Lipase ZK262.3 (EC 3.1.1.-) Caenorhabditis elegans lipid catabolic process [GO:0016042] GO:0005576; GO:0016042; GO:0016787 25226 XM_029330660.2 1470 904 598 1017 1046 NA NA NA NA NA NA 25227 XM_029338486.2 1673 4161 878 4271 3910 Q9DB30 3.21e-136 Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) (EC 2.7.11.19) (Phosphorylase kinase subunit gamma-2) Mus musculus (Mouse) glycogen biosynthetic process [GO:0005978]; glycogen catabolic process [GO:0005980]; glycogen metabolic process [GO:0005977]; protein phosphorylation [GO:0006468] GO:0004689; GO:0005516; GO:0005524; GO:0005829; GO:0005964; GO:0005977; GO:0005978; GO:0005980; GO:0006468; GO:0008047; GO:0019899 25228 XM_044314981.1 45 3 0 6 21 NA NA NA NA NA NA 25229 XM_044326840.1 7 0 0 0 9 Q9VBW3 1.07e-62 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 25230 XM_029357285.2 383 130 208 238 97 P31646 3.58e-112 Sodium- and chloride-dependent GABA transporter 2 (GAT-2) (Solute carrier family 6 member 13) Rattus norvegicus (Rat) amino acid import across plasma membrane [GO:0089718]; creatine transmembrane transport [GO:0015881]; gamma-aminobutyric acid import [GO:0051939]; monocarboxylic acid transport [GO:0015718]; neurotransmitter transport [GO:0006836]; nitrogen compound transport [GO:0071705]; positive regulation of necrotic cell death [GO:0010940]; sodium ion transmembrane transport [GO:0035725]; taurine transport [GO:0015734] GO:0005283; GO:0005308; GO:0005332; GO:0005368; GO:0005369; GO:0005886; GO:0006836; GO:0008028; GO:0010940; GO:0015171; GO:0015185; GO:0015718; GO:0015734; GO:0015881; GO:0016323; GO:0035725; GO:0042165; GO:0043005; GO:0051939; GO:0071705; GO:0089718 25231 XM_044321911.1 13 36 0 2 0 NA NA NA NA NA NA 25232 XM_029337973.2 210 0 91 179 0 NA NA NA NA NA NA 25233 XR_003826734.2 24 0 24 0 27 NA NA NA NA NA NA 25234 XM_044306880.1 39 0 22 70 219 P98192 1.88e-105 Dihydroxyacetone phosphate acyltransferase (DAP-AT) (DHAP-AT) (EC 2.3.1.42) (Acyl-CoA:dihydroxyacetonephosphateacyltransferase) (Glycerone-phosphate O-acyltransferase) Mus musculus (Mouse) cerebellum morphogenesis [GO:0021587]; ether lipid biosynthetic process [GO:0008611]; fatty acid metabolic process [GO:0006631]; glycerophospholipid metabolic process [GO:0006650]; membrane organization [GO:0061024]; myelination [GO:0042552]; paranodal junction assembly [GO:0030913]; phospholipid biosynthetic process [GO:0008654]; response to fatty acid [GO:0070542]; response to nutrient [GO:0007584]; response to starvation [GO:0042594]; response to xenobiotic stimulus [GO:0009410]; synapse assembly [GO:0007416] GO:0003824; GO:0005739; GO:0005777; GO:0005778; GO:0005782; GO:0006631; GO:0006650; GO:0007416; GO:0007584; GO:0008611; GO:0008654; GO:0009410; GO:0016287; GO:0021587; GO:0030913; GO:0031966; GO:0042552; GO:0042594; GO:0061024; GO:0070542 25235 XM_029332305.2 5746 4280 2596 4567 5063 Q9EQH3 0 Vacuolar protein sorting-associated protein 35 (Maternal-embryonic 3) (Vesicle protein sorting 35) Mus musculus (Mouse) endocytic recycling [GO:0032456]; intracellular protein transport [GO:0006886]; lysosome organization [GO:0007040]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; mitochondrion to lysosome transport [GO:0099074]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of cell death [GO:0060548]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of late endosome to lysosome transport [GO:1902823]; negative regulation of lysosomal protein catabolic process [GO:1905166]; negative regulation of neuron death [GO:1901215]; negative regulation of protein homooligomerization [GO:0032463]; negative regulation of protein localization [GO:1903828]; neurotransmitter receptor transport, endosome to plasma membrane [GO:0099639]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of dopamine biosynthetic process [GO:1903181]; positive regulation of dopamine receptor signaling pathway [GO:0060161]; positive regulation of gene expression [GO:0010628]; positive regulation of locomotion involved in locomotory behavior [GO:0090326]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of Wnt protein secretion [GO:0061357]; protein destabilization [GO:0031648]; protein localization to endosome [GO:0036010]; protein localization to organelle [GO:0033365]; regulation of dendritic spine maintenance [GO:1902950]; regulation of mitochondrion organization [GO:0010821]; regulation of postsynapse assembly [GO:0150052]; regulation of protein metabolic process [GO:0051246]; regulation of protein stability [GO:0031647]; regulation of synapse maturation [GO:0090128]; regulation of terminal button organization [GO:2000331]; retrograde transport, endosome to Golgi [GO:0042147]; transcytosis [GO:0045056]; vacuolar protein processing [GO:0006624]; vesicle-mediated transport in synapse [GO:0099003]; voluntary musculoskeletal movement [GO:0050882] GO:0005737; GO:0005739; GO:0005764; GO:0005768; GO:0005769; GO:0005770; GO:0005829; GO:0006624; GO:0006886; GO:0007040; GO:0010008; GO:0010628; GO:0010629; GO:0010821; GO:0014069; GO:0016020; GO:0030904; GO:0030906; GO:0031647; GO:0031648; GO:0031748; GO:0032456; GO:0032463; GO:0033365; GO:0036010; GO:0042147; GO:0043005; GO:0043025; GO:0043653; GO:0045056; GO:0045202; GO:0045732; GO:0048471; GO:0050728; GO:0050804; GO:0050882; GO:0051246; GO:0060161; GO:0060548; GO:0061357; GO:0090128; GO:0090141; GO:0090263; GO:0090326; GO:0097422; GO:0098691; GO:0098793; GO:0098794; GO:0098887; GO:0098978; GO:0099003; GO:0099073; GO:0099074; GO:0099639; GO:0150052; GO:1901215; GO:1902823; GO:1902950; GO:1903181; GO:1903828; GO:1905166; GO:2000331 25236 XM_044311969.1 66 7 53 23 109 Q5XI13 2.89e-36 Glutamate-rich WD repeat-containing protein 1 Rattus norvegicus (Rat) DNA replication [GO:0006260]; nucleosome assembly [GO:0006334]; nucleosome disassembly [GO:0006337]; ribosome biogenesis [GO:0042254] GO:0003682; GO:0003688; GO:0005634; GO:0005694; GO:0005730; GO:0006260; GO:0006334; GO:0006337; GO:0032991; GO:0042254; GO:0042393 25237 XM_044311969.1 66 7 53 23 109 Q5XI13 2.89e-36 Glutamate-rich WD repeat-containing protein 1 Rattus norvegicus (Rat) DNA replication [GO:0006260]; nucleosome assembly [GO:0006334]; nucleosome disassembly [GO:0006337]; ribosome biogenesis [GO:0042254] GO:0003682; GO:0003688; GO:0005634; GO:0005694; GO:0005730; GO:0006260; GO:0006334; GO:0006337; GO:0032991; GO:0042254; GO:0042393 25238 XM_029335074.2 63 56 141 93 13 NA NA NA NA NA NA 25239 XM_044320307.1 40 0 10 52 7 O70244 3.11e-73 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 25240 XM_044320307.1 40 0 10 52 7 O70244 8.54e-65 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 25241 XM_044320307.1 40 0 10 52 7 O70244 2.84e-62 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 25242 XM_044320307.1 40 0 10 52 7 O70244 3.82e-62 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 25243 XM_044320307.1 40 0 10 52 7 O70244 1.02e-58 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 25244 XM_044320307.1 40 0 10 52 7 O70244 2.77e-52 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 25245 XM_044320307.1 40 0 10 52 7 O70244 1.64e-48 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 25246 XR_006398131.1 28 39 39 15 95 F6QEU4 1.23e-44 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 25247 XR_006398131.1 28 39 39 15 95 F6QEU4 1.23e-44 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 25248 XM_044326805.1 64 123 28 0 23 NA NA NA NA NA NA 25249 XM_044323228.1 131 0 15 602 890 NA NA NA NA NA NA 25250 XM_029340416.2 10 5 0 5 0 NA NA NA NA NA NA 25251 XM_044327700.1 3 4 6 8 17 NA NA NA NA NA NA 25252 XM_029332609.2 30 101 30 42 62 NA NA NA NA NA NA 25253 XR_006394718.1 22 41 19 12 14 NA NA NA NA NA NA 25254 XM_044323471.1 13 87 35 37 30 NA NA NA NA NA NA 25255 XM_044317566.1 15 9 4 2 24 NA NA NA NA NA NA 25256 XM_044328206.1 125 1 7 0 113 NA NA NA NA NA NA 25257 XR_003827363.2 0 0 0 6 0 NA NA NA NA NA NA 25258 XM_044319264.1 522 514 99 815 494 Q9NQQ7 1.43e-93 Solute carrier family 35 member C2 (Ovarian cancer-overexpressed gene 1 protein) Homo sapiens (Human) negative regulation of gene expression [GO:0010629]; positive regulation of Notch signaling pathway [GO:0045747]; protein O-linked fucosylation [GO:0036066]; UDP-glucose transmembrane transport [GO:0015786] GO:0005654; GO:0005793; GO:0005794; GO:0005801; GO:0010629; GO:0015297; GO:0015786; GO:0033116; GO:0036066; GO:0045747 25259 XM_044325583.1 309 68 87 254 197 NA NA NA NA NA NA 25260 XM_029345275.2 14 5 10 16 3 NA NA NA NA NA NA 25261 XM_029355396.2 20 5 10 22 19 NA NA NA NA NA NA 25262 XM_044316179.1 26 61 119 124 113 NA NA NA NA NA NA 25263 XM_029357338.2 259 0 13 0 47 P22770 3.22e-72 Neuronal acetylcholine receptor subunit alpha-7 Gallus gallus (Chicken) calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; cognition [GO:0050890]; membrane depolarization [GO:0051899]; negative regulation of tumor necrosis factor production [GO:0032720]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAPK cascade [GO:0043410]; regulation of nitric oxide metabolic process [GO:0080164]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; signal transduction [GO:0007165] GO:0001540; GO:0001666; GO:0005737; GO:0005886; GO:0005892; GO:0006816; GO:0006874; GO:0007165; GO:0008284; GO:0015464; GO:0015643; GO:0017081; GO:0022848; GO:0030424; GO:0030425; GO:0032720; GO:0035094; GO:0042166; GO:0042803; GO:0043204; GO:0043410; GO:0045211; GO:0045766; GO:0050890; GO:0051899; GO:0080164 25264 XM_044320456.1 0 566 564 189 856 Q5RJF7 9.71e-104 Voltage-dependent calcium channel subunit alpha-2/delta-4 (Voltage-gated calcium channel subunit alpha-2/delta-4) [Cleaved into: Voltage-dependent calcium channel subunit alpha-2-4; Voltage-dependent calcium channel subunit delta-4] Mus musculus (Mouse) calcium ion transmembrane transport [GO:0070588]; detection of light stimulus involved in visual perception [GO:0050908]; regulation of ion transmembrane transport [GO:0034765] GO:0005245; GO:0005891; GO:0034765; GO:0046872; GO:0050908; GO:0070588 25265 XM_044317215.1 0 0 181 0 0 NA NA NA NA NA NA 25266 XM_044322285.1 43 16 21 73 0 NA NA NA NA NA NA 25267 XM_044323869.1 478 483 162 157 196 NA NA NA NA NA NA 25268 XM_044326649.1 109 182 199 70 41 NA NA NA NA NA NA 25269 XM_029337955.2 16 31 28 27 50 Q8BMN3 8.95e-64 Neuronal acetylcholine receptor subunit beta-3 Mus musculus (Mouse) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system process [GO:0050877]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of membrane potential [GO:0042391]; response to nicotine [GO:0035094]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271] GO:0004888; GO:0005231; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0007271; GO:0016020; GO:0022848; GO:0030594; GO:0032991; GO:0034220; GO:0035094; GO:0042166; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051899; GO:0098691; GO:0098793; GO:0099171; GO:1901363; GO:1904315 25270 XM_044324302.1 398 522 522 619 418 NA NA NA NA NA NA 25271 XR_006396095.1 1744 1154 706 2251 1331 NA NA NA NA NA NA 25272 XM_029355781.2 170 66 89 20 0 Q9EQD2 5.49e-35 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 25273 XM_044328901.1 9 1 11 0 22 NA NA NA NA NA NA 25274 XM_029356599.2 390 634 273 243 410 F1N2K1 1.93e-80 Prenylcysteine oxidase 1 (EC 1.8.3.5) (Prenylcysteine lyase) Bos taurus (Bovine) prenylated protein catabolic process [GO:0030327]; prenylcysteine catabolic process [GO:0030328] GO:0001735; GO:0005764; GO:0030327; GO:0030328; GO:0034361; GO:0071949 25275 XM_044310913.1 16 6 103 42 24 NA NA NA NA NA NA 25276 XM_029339918.2 0 145 0 208 0 P31422 0 Metabotropic glutamate receptor 3 (mGluR3) Rattus norvegicus (Rat) G protein-coupled glutamate receptor signaling pathway [GO:0007216]; gene expression [GO:0010467]; modulation of chemical synaptic transmission [GO:0050804]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; regulation of synaptic transmission, glutamatergic [GO:0051966]; sensory perception of pain [GO:0019233] GO:0001640; GO:0001641; GO:0005246; GO:0005886; GO:0007216; GO:0010467; GO:0014069; GO:0019233; GO:0030424; GO:0042734; GO:0043005; GO:0043197; GO:0045211; GO:0050804; GO:0051966; GO:0097110; GO:0097449; GO:0098794; GO:0098978; GO:0099170 25277 XM_029336215.2 0 2 1 10 8 NA NA NA NA NA NA 25278 XM_044314123.1 0 0 6 0 0 Q9CUX1 3.46e-22 52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (THAP domain-containing protein 0) (THAP domain-containing protein 12) Mus musculus (Mouse) NA GO:0003677; GO:0005634; GO:0046872; GO:0046983 25279 XM_029354440.2 0 33 0 0 0 NA NA NA NA NA NA 25280 XM_044320279.1 1469 1085 1157 1832 2560 Q8TE73 0 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5) Homo sapiens (Human) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0005524; GO:0005576; GO:0005737; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 25281 XM_044320279.1 1469 1085 1157 1832 2560 Q8TE73 0 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5) Homo sapiens (Human) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0005524; GO:0005576; GO:0005737; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 25282 XM_029353608.2 64 19 23 33 27 Q96AY4 1.74e-101 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25283 XM_029353608.2 64 19 23 33 27 Q96AY4 2.69e-85 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25284 XM_029353608.2 64 19 23 33 27 Q96AY4 2.54e-83 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25285 XM_029353608.2 64 19 23 33 27 Q96AY4 6.92e-72 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25286 XM_029353608.2 64 19 23 33 27 Q96AY4 5.93e-66 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25287 XM_029353608.2 64 19 23 33 27 Q96AY4 7.28e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25288 XM_029358159.2 553 511 601 838 684 Q9DC48 0 Pre-mRNA-processing factor 17 (Cell division cycle 40 homolog) (PRP17 homolog) Mus musculus (Mouse) embryonic brain development [GO:1990403]; mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0003729; GO:0005654; GO:0016607; GO:0071007; GO:0071013; GO:1990403 25289 XM_029358622.2 855 689 494 1242 1310 Q8SZA8 1.21e-34 Adrenodoxin-like protein 2, mitochondrial (Ferredoxin-2) Drosophila melanogaster (Fruit fly) electron transport chain [GO:0022900]; P450-containing electron transport chain [GO:0140647]; positive regulation of ecdysteroid biosynthetic process [GO:0045998]; positive regulation of oxidoreductase activity [GO:0051353]; steroid biosynthetic process [GO:0006694] GO:0005739; GO:0006694; GO:0009055; GO:0022900; GO:0045998; GO:0046872; GO:0051353; GO:0051537; GO:0140647 25290 XM_029358051.2 540 360 233 348 386 Q6VYA3 1.27e-24 Sclerostin domain-containing protein 1 (Wnt-signaling modulator) Gallus gallus (Chicken) negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of Wnt signaling pathway [GO:0030178]; Wnt signaling pathway [GO:0016055] GO:0005615; GO:0016055; GO:0030178; GO:0030514; GO:0036122 25291 XM_044322169.1 275 80 126 447 391 Q8IS64 5.95e-149 Endothelin-converting enzyme homolog (ECE) (EC 3.4.24.-) Locusta migratoria (Migratory locust) proteolysis [GO:0006508] GO:0004175; GO:0004222; GO:0005886; GO:0006508; GO:0008270 25292 XM_029351307.2 0 0 13 0 6 NA NA NA NA NA NA 25293 XM_029326931.2 1458 399 549 1267 607 NA NA NA NA NA NA 25294 XM_029332658.2 11783 14667 10511 11812 9074 P51644 4.18e-106 ADP-ribosylation factor 4 Xenopus laevis (African clawed frog) protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] GO:0003924; GO:0005525; GO:0005794; GO:0015031; GO:0016192 25295 XM_044328719.1 149 52 95 23 310 NA NA NA NA NA NA 25296 XM_044307408.1 2 0 8 5 16 NA NA NA NA NA NA 25297 XM_044307782.1 470 226 365 483 399 A7RZW4 0 Dipeptidyl peptidase 3 (EC 3.4.14.4) (Dipeptidyl aminopeptidase III) (Dipeptidyl arylamidase III) (Dipeptidyl peptidase III) (DPP III) Nematostella vectensis (Starlet sea anemone) proteolysis [GO:0006508] GO:0004177; GO:0005737; GO:0006508; GO:0008235; GO:0008239; GO:0046872 25298 XM_029348398.2 61 0 86 614 728 Q9JJS6 6.78e-106 Beta,beta-carotene 15,15'-dioxygenase (EC 1.13.11.63) (Beta-carotene dioxygenase 1) (Beta-carotene oxygenase 1) Mus musculus (Mouse) beta-carotene metabolic process [GO:1901810]; carotene catabolic process [GO:0016121]; retinal metabolic process [GO:0042574]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572] GO:0001523; GO:0003834; GO:0005829; GO:0010436; GO:0016121; GO:0042572; GO:0042574; GO:0046872; GO:1901810 25299 XM_029350671.2 805 414 231 469 155 P54288 5.45e-125 Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2) Oryctolagus cuniculus (Rabbit) calcium ion import [GO:0070509]; chemical synaptic transmission [GO:0007268]; membrane depolarization during atrial cardiac muscle cell action potential [GO:0098912]; positive regulation of calcium ion transport [GO:0051928]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ion transmembrane transport [GO:0034765]; visual perception [GO:0007601] GO:0007268; GO:0007601; GO:0008331; GO:0034765; GO:0051015; GO:0051928; GO:0070509; GO:0086056; GO:0086091; GO:0098684; GO:0098793; GO:0098912; GO:0099626; GO:1990454 25300 XM_029338874.2 257 658 378 421 482 Q566C7 3.45e-44 Diphosphoinositol polyphosphate phosphohydrolase 1 (DIPP-1) (EC 3.6.1.52) (Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 1) (EC 3.6.1.-) (Nucleoside diphosphate-linked moiety X motif 3) (Nudix motif 3) Rattus norvegicus (Rat) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process [GO:1901911]; diadenosine hexaphosphate catabolic process [GO:1901909]; diadenosine pentaphosphate catabolic process [GO:1901907]; diphosphoinositol polyphosphate catabolic process [GO:0071544]; diphosphoinositol polyphosphate metabolic process [GO:0071543]; RNA decapping [GO:0110154] GO:0000287; GO:0000298; GO:0005634; GO:0005737; GO:0005829; GO:0008486; GO:0034431; GO:0034432; GO:0050072; GO:0052840; GO:0052842; GO:0052845; GO:0052848; GO:0071543; GO:0071544; GO:0110154; GO:1901907; GO:1901909; GO:1901911 25301 XM_029343098.2 0 4 2 2 12 NA NA NA NA NA NA 25302 XM_044316175.1 4 1 0 11 53 NA NA NA NA NA NA 25303 XM_044322975.1 208 0 43 51 146 Q838D6 2.33e-61 L-tyrosine decarboxylase (TDC) (EC 4.1.1.25) (Levodopa decarboxylase) (L-dopa decarboxylase) (EC 4.1.1.-) Enterococcus faecalis (strain ATCC 700802 / V583) L-dopa metabolic process [GO:1903184] GO:0004837; GO:0030170; GO:0036468; GO:1903184 25304 XM_044314621.1 0 0 5 23 12 NA NA NA NA NA NA 25305 XM_029345686.2 20 3 16 26 24 A6QLU6 2.27e-66 Adhesion G-protein coupled receptor D1 (G-protein coupled receptor 133) Bos taurus (Bovine) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0005886; GO:0007166; GO:0007186; GO:0007189 25306 XM_044310871.1 330 0 116 4 163 NA NA NA NA NA NA 25307 XM_029343364.2 4519 4711 2508 4699 2939 A7SA47 4.17e-163 Eukaryotic translation initiation factor 3 subunit H (eIF3h) Nematostella vectensis (Starlet sea anemone) formation of cytoplasmic translation initiation complex [GO:0001732] GO:0001732; GO:0003743; GO:0005852; GO:0008237; GO:0016282; GO:0033290; GO:0042788 25308 XM_029357569.2 622 757 625 1539 955 Q9D9S1 3.74e-38 UPF0193 protein EVG1 homolog Mus musculus (Mouse) NA NA 25309 XM_044315959.1 27 1 19 1 50 NA NA NA NA NA NA 25310 XM_044326928.1 5 0 12 2 48 NA NA NA NA NA NA 25311 XM_044318538.1 130 93 140 151 160 Q96AY4 1.14e-139 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25312 XM_044318538.1 130 93 140 151 160 Q96AY4 1.57e-131 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25313 XM_044318538.1 130 93 140 151 160 Q96AY4 1.07e-107 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25314 XM_044318538.1 130 93 140 151 160 Q96AY4 6.47e-70 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25315 XM_044318538.1 130 93 140 151 160 Q96AY4 1.01e-37 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25316 XM_044318538.1 130 93 140 151 160 Q96AY4 4.91e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25317 XR_006396325.1 52 39 57 95 196 NA NA NA NA NA NA 25318 XM_029330372.2 511 390 353 329 506 O14681 5.27e-60 Etoposide-induced protein 2.4 homolog (p53-induced gene 8 protein) Homo sapiens (Human) apoptotic process [GO:0006915]; macroautophagy [GO:0016236]; negative regulation of cell growth [GO:0030308] GO:0005783; GO:0005789; GO:0005794; GO:0005829; GO:0006915; GO:0016020; GO:0016236; GO:0030308; GO:0031965; GO:0061676 25319 XM_044327345.1 1 0 0 0 11 NA NA NA NA NA NA 25320 XM_029355508.2 441 497 276 732 484 P42587 3.53e-33 Homeobox protein XENK-2 Xenopus laevis (African clawed frog) NA GO:0000981; GO:0003677; GO:0005634 25321 XM_029339313.2 30 0 79 33 31 Q9JI13 1.32e-30 Something about silencing protein 10 (Charged amino acid-rich leucine zipper 1) (Crl-1) (Disrupter of silencing SAS10) (UTP3 homolog) Mus musculus (Mouse) brain development [GO:0007420]; chromatin organization [GO:0006325]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462] GO:0000462; GO:0005634; GO:0005730; GO:0006325; GO:0007420; GO:0032040 25322 XR_003825032.2 14 24 33 7 63 NA NA NA NA NA NA 25323 XM_044328626.1 81 21 105 27 491 NA NA NA NA NA NA 25324 XM_029329676.2 248 346 219 325 183 NA NA NA NA NA NA 25325 XM_044317594.1 46 137 270 245 296 NA NA NA NA NA NA 25326 XM_029336454.2 49 40 72 64 192 Q91ZW6 6.16e-84 Trimethyllysine dioxygenase, mitochondrial (EC 1.14.11.8) (Epsilon-trimethyllysine 2-oxoglutarate dioxygenase) (TML hydroxylase) (TML-alpha-ketoglutarate dioxygenase) (TML dioxygenase) (TMLD) Rattus norvegicus (Rat) carnitine biosynthetic process [GO:0045329] GO:0005506; GO:0005739; GO:0005759; GO:0016702; GO:0045329; GO:0050353 25327 XM_029325153.2 1330 1576 798 1106 1034 Q8L7W2 1.56e-48 Nudix hydrolase 8 (AtNUDT8) (EC 3.6.1.-) Arabidopsis thaliana (Mouse-ear cress) response to wounding [GO:0009611] GO:0005829; GO:0009611; GO:0035529; GO:0046872; GO:0047631; GO:0051287 25328 XM_029345385.2 3485 2158 1473 2780 2504 Q98TX3 3.67e-87 Programmed cell death protein 4 (Protein I11/6) Gallus gallus (Chicken) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of JUN kinase activity [GO:0043508] GO:0003723; GO:0005634; GO:0005737; GO:0005829; GO:0043508; GO:0045892 25329 XM_029346754.2 162 241 274 186 144 NA NA NA NA NA NA 25330 XR_006396872.1 26 27 46 27 134 NA NA NA NA NA NA 25331 XM_044328442.1 5320 5209 3629 5730 4406 Q99KI0 0 Aconitate hydratase, mitochondrial (Aconitase) (EC 4.2.1.3) (Citrate hydro-lyase) Mus musculus (Mouse) citrate metabolic process [GO:0006101]; isocitrate metabolic process [GO:0006102]; liver development [GO:0001889]; response to isolation stress [GO:0035900]; tricarboxylic acid cycle [GO:0006099] GO:0001889; GO:0003994; GO:0005506; GO:0005739; GO:0005759; GO:0005829; GO:0006099; GO:0006101; GO:0006102; GO:0035900; GO:0043209; GO:0047780; GO:0051538; GO:0051539 25332 XM_029325954.2 330 443 401 772 541 NA NA NA NA NA NA 25333 XM_044308497.1 1 0 7 8 4 A6NMZ7 2.66e-77 Collagen alpha-6(VI) chain Homo sapiens (Human) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 25334 XM_029338019.2 78 73 57 80 113 Q7TN88 4.73e-79 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 25335 XM_029338019.2 78 73 57 80 113 Q7TN88 1.86e-66 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 25336 XM_044325619.1 11 2 13 6 23 Q70E20 1.98e-29 Sushi, nidogen and EGF-like domain-containing protein 1 (Secreted protein SST-3) (Stromal nidogen extracellular matrix protein) Mus musculus (Mouse) cell-matrix adhesion [GO:0007160] GO:0005112; GO:0005509; GO:0005576; GO:0007160; GO:0031012 25337 XM_044325619.1 11 2 13 6 23 Q70E20 2.48e-24 Sushi, nidogen and EGF-like domain-containing protein 1 (Secreted protein SST-3) (Stromal nidogen extracellular matrix protein) Mus musculus (Mouse) cell-matrix adhesion [GO:0007160] GO:0005112; GO:0005509; GO:0005576; GO:0007160; GO:0031012 25338 XM_044325619.1 11 2 13 6 23 Q70E20 4.47e-22 Sushi, nidogen and EGF-like domain-containing protein 1 (Secreted protein SST-3) (Stromal nidogen extracellular matrix protein) Mus musculus (Mouse) cell-matrix adhesion [GO:0007160] GO:0005112; GO:0005509; GO:0005576; GO:0007160; GO:0031012 25339 XM_044309824.1 662 519 394 855 504 NA NA NA NA NA NA 25340 XR_006396751.1 13 0 0 0 0 NA NA NA NA NA NA 25341 XM_029334713.2 66 9 36 125 36 O54852 0 Potassium voltage-gated channel subfamily H member 7 (Ether-a-go-go-related gene potassium channel 3) (ERG-3) (Eag-related protein 3) (Ether-a-go-go-related protein 3) (Voltage-gated potassium channel subunit Kv11.3) Rattus norvegicus (Rat) circadian rhythm [GO:0007623]; membrane repolarization during action potential [GO:0086011]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391] GO:0005242; GO:0005249; GO:0005267; GO:0005886; GO:0006813; GO:0007623; GO:0034765; GO:0042391; GO:0044877; GO:0071805; GO:0086011 25342 XM_029343935.2 122 22 21 109 1309 NA NA NA NA NA NA 25343 XM_029352900.2 3596 3633 2748 4872 7485 P38646 0 Stress-70 protein, mitochondrial (75 kDa glucose-regulated protein) (GRP-75) (Heat shock 70 kDa protein 9) (Mortalin) (MOT) (Peptide-binding protein 74) (PBP74) Homo sapiens (Human) cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; erythrocyte differentiation [GO:0030218]; inner mitochondrial membrane organization [GO:0007007]; intracellular protein transport [GO:0006886]; iron-sulfur cluster assembly [GO:0016226]; negative regulation of apoptotic process [GO:0043066]; negative regulation of erythrocyte differentiation [GO:0045647]; negative regulation of hematopoietic stem cell differentiation [GO:1902037]; negative regulation of hemopoiesis [GO:1903707]; protein export from nucleus [GO:0006611]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646] GO:0001401; GO:0003723; GO:0005524; GO:0005730; GO:0005737; GO:0005739; GO:0005744; GO:0005759; GO:0005925; GO:0006611; GO:0006886; GO:0007007; GO:0016226; GO:0016887; GO:0030218; GO:0031072; GO:0031625; GO:0034620; GO:0042026; GO:0042645; GO:0043066; GO:0044183; GO:0045646; GO:0045647; GO:0051082; GO:0051085; GO:0051787; GO:0070062; GO:0140275; GO:0140662; GO:1902037; GO:1903707 25344 XM_044321489.1 81 30 78 26 92 Q9SY14 2.95e-68 CSC1-like protein At4g02900 Arabidopsis thaliana (Mouse-ear cress) NA GO:0005227; GO:0005886 25345 XM_044321786.1 87 39 83 1 0 NA NA NA NA NA NA 25346 XM_029350803.2 989 631 420 670 919 A7RNG8 0 Coiled-coil domain-containing protein 22 homolog Nematostella vectensis (Starlet sea anemone) positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060] GO:0097602; GO:2000060 25347 XM_044323603.1 481 292 476 643 763 B8JK39 1.97e-102 Integrin alpha-9 Mus musculus (Mouse) cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; neutrophil chemotaxis [GO:0030593]; wound healing [GO:0042060] GO:0005178; GO:0005518; GO:0007155; GO:0007160; GO:0007229; GO:0008305; GO:0009897; GO:0009925; GO:0016020; GO:0030593; GO:0033627; GO:0034679; GO:0042060; GO:0043236; GO:0046872; GO:0050900; GO:0098609 25348 XM_044321396.1 34 0 7 2 100 P46023 2.77e-96 G-protein coupled receptor GRL101 Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004930; GO:0005886 25349 XM_044324802.1 729 538 389 492 526 Q9Y2G3 0 Phospholipid-transporting ATPase IF (EC 7.6.2.1) (ATPase IR) (ATPase class VI type 11B) (P4-ATPase flippase complex alpha subunit ATP11B) Homo sapiens (Human) aminophospholipid transport [GO:0015917]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; phospholipid translocation [GO:0045332] GO:0000287; GO:0005524; GO:0005637; GO:0005783; GO:0005802; GO:0005886; GO:0006811; GO:0015075; GO:0015917; GO:0016020; GO:0016887; GO:0031901; GO:0034220; GO:0035577; GO:0045332; GO:0055037; GO:0055038; GO:0090555; GO:0090556; GO:0140326; GO:1990531 25350 XR_006394463.1 5 0 7 27 17 NA NA NA NA NA NA 25351 XM_044324755.1 31 25 15 6 143 NA NA NA NA NA NA 25352 XM_044324237.1 0 0 0 0 55 NA NA NA NA NA NA 25353 XM_044316875.1 128 71 109 50 100 Q5EBD9 0 Elongator complex protein 2 (ELP2) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) proteasome assembly [GO:0043248]; transcription elongation by RNA polymerase II promoter [GO:0006368]; tRNA wobble uridine modification [GO:0002098] GO:0000502; GO:0002098; GO:0005634; GO:0005737; GO:0006368; GO:0033588; GO:0043248; GO:0061133 25354 XM_029323841.2 338 200 241 268 411 Q6TNS2 5.65e-79 p21-activated protein kinase-interacting protein 1-like (PAK1-interacting protein 1-like) Danio rerio (Zebrafish) (Brachydanio rerio) negative regulation of signal transduction [GO:0009968]; ribosomal large subunit biogenesis [GO:0042273] GO:0005730; GO:0009968; GO:0042273 25355 XR_006392247.1 9 1 15 11 6 NA NA NA NA NA NA 25356 XM_044325870.1 589 216 359 886 0 NA NA NA NA NA NA 25357 XM_044319043.1 142 263 225 302 129 NA NA NA NA NA NA 25358 XM_044306997.1 239 269 247 463 564 NA NA NA NA NA NA 25359 XM_029348736.2 1207 772 336 563 829 Q8N309 3.57e-46 Leucine-rich repeat-containing protein 43 Homo sapiens (Human) positive regulation of protein dephosphorylation [GO:0035307] GO:0000164; GO:0004865; GO:0035307 25360 XM_029332122.2 1864 1279 1066 1207 991 NA NA NA NA NA NA 25361 XM_044323507.1 5 0 7 0 44 NA NA NA NA NA NA 25362 XM_029356853.2 17 6 9 12 36 NA NA NA NA NA NA 25363 XM_044306793.1 1742 1062 1185 1944 2118 Q8TD19 0 Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (Nercc1 kinase) (Never in mitosis A-related kinase 9) (NimA-related protein kinase 9) (NimA-related kinase 8) (Nek8) Homo sapiens (Human) cell division [GO:0051301]; mitotic cell cycle [GO:0000278]; protein phosphorylation [GO:0006468] GO:0000278; GO:0004674; GO:0005524; GO:0005634; GO:0005829; GO:0006468; GO:0019901; GO:0030295; GO:0046872; GO:0051301; GO:0106310 25364 XM_044316776.1 0 0 11 3 0 NA NA NA NA NA NA 25365 XM_044321282.1 0 0 0 14 0 B6ELU0 1.68e-40 tRNA-cytidine(32) 2-sulfurtransferase (EC 2.8.1.-) (Two-thiocytidine biosynthesis protein A) (tRNA 2-thiocytidine biosynthesis protein TtcA) Aliivibrio salmonicida (strain LFI1238) (Vibrio salmonicida (strain LFI1238)) tRNA thio-modification [GO:0034227] GO:0000049; GO:0000287; GO:0005524; GO:0005737; GO:0016783; GO:0034227; GO:0051539 25366 XR_003825311.1 2 1 0 0 9 NA NA NA NA NA NA 25367 XR_006391810.1 5 0 0 9 37 NA NA NA NA NA NA 25368 XM_044310611.1 3309 2369 1698 4210 4535 P31836 3.42e-42 Neural cell adhesion molecule 1 (N-CAM-1) (NCAM-1) Bos taurus (Bovine) axon guidance [GO:0007411]; dendrite self-avoidance [GO:0070593]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005886; GO:0007156; GO:0007411; GO:0030424; GO:0070593; GO:0098632 25369 XM_029324181.2 35 61 55 91 122 Q3B8H4 6.53e-63 Rhombotin-1 (LIM domain only protein 1) (LMO-1) Xenopus laevis (African clawed frog) NA GO:0005634; GO:0046872 25370 XM_029335872.2 73 4 3 16 14 A6QLE6 5.54e-176 Anoctamin-4 (Transmembrane protein 16D) Bos taurus (Bovine) chloride transmembrane transport [GO:1902476]; lipid transport [GO:0006869]; transmembrane transport [GO:0055085] GO:0005229; GO:0005254; GO:0005886; GO:0006869; GO:0046983; GO:0055085; GO:1902476 25371 XM_029351022.2 13 0 0 8 4 NA NA NA NA NA NA 25372 XM_029334089.2 619 902 405 381 429 NA NA NA NA NA NA 25373 XM_029324500.2 567 540 419 495 595 Q99JB0 2.42e-54 Krueppel-like factor 7 Mus musculus (Mouse) axon guidance [GO:0007411]; axonogenesis [GO:0007409]; dendrite morphogenesis [GO:0048813]; glucose homeostasis [GO:0042593]; negative regulation of adipose tissue development [GO:1904178]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of epidermal cell differentiation [GO:0045604]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000978; GO:0000981; GO:0001228; GO:0003677; GO:0003700; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0007409; GO:0007411; GO:0042593; GO:0045604; GO:0045893; GO:0045944; GO:0046872; GO:0048813; GO:0061179; GO:1904178 25374 XM_044309604.1 9 8 36 47 65 P08548 1.35e-35 LINE-1 reverse transcriptase homolog (EC 2.7.7.49) Nycticebus coucang (Slow loris) NA GO:0003964; GO:0046872 25375 XM_044323843.1 17 13 30 96 0 P08419 8.47e-48 Chymotrypsin-like elastase family member 2A (EC 3.4.21.71) (Elastase-2) (Elastase-2A) Sus scrofa (Pig) insulin catabolic process [GO:1901143]; proteolysis [GO:0006508]; regulation of insulin secretion [GO:0050796]; regulation of platelet aggregation [GO:0090330]; response to insulin [GO:0032868] GO:0004175; GO:0004252; GO:0005576; GO:0005615; GO:0006508; GO:0032868; GO:0050796; GO:0090330; GO:1901143 25376 XM_029350411.2 61 68 29 36 38 Q96AY4 3.24e-58 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25377 XM_029350411.2 61 68 29 36 38 Q96AY4 7.06e-58 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25378 XM_029350411.2 61 68 29 36 38 Q96AY4 5.94e-54 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25379 XM_029350411.2 61 68 29 36 38 Q96AY4 1.42e-53 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25380 XM_029350411.2 61 68 29 36 38 Q96AY4 1.4e-47 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25381 XM_029350411.2 61 68 29 36 38 Q96AY4 4.32e-47 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25382 XM_029350411.2 61 68 29 36 38 Q96AY4 8.86e-46 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25383 XM_029350411.2 61 68 29 36 38 Q96AY4 7.18e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25384 XM_029350411.2 61 68 29 36 38 Q96AY4 2.3e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25385 XM_029350411.2 61 68 29 36 38 Q96AY4 6.05e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25386 XM_029350411.2 61 68 29 36 38 Q96AY4 1.74e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25387 XM_029344991.2 27 1 0 0 87 NA NA NA NA NA NA 25388 XM_044307933.1 0 0 7 2 0 NA NA NA NA NA NA 25389 XM_044313002.1 21 0 0 0 8 NA NA NA NA NA NA 25390 XM_044319989.1 0 36 0 0 0 NA NA NA NA NA NA 25391 XM_029342442.2 0 5 3 0 49 NA NA NA NA NA NA 25392 XM_029339081.2 470 393 327 592 996 Q9BZE4 0 GTP-binding protein 4 (Chronic renal failure gene protein) (GTP-binding protein NGB) (Nucleolar GTP-binding protein 1) Homo sapiens (Human) maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of collagen binding [GO:0033342]; negative regulation of DNA replication [GO:0008156]; negative regulation of protein ubiquitination [GO:0031397]; osteoblast differentiation [GO:0001649]; protein stabilization [GO:0050821]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; ribosomal large subunit biogenesis [GO:0042273] GO:0000079; GO:0000463; GO:0001649; GO:0003723; GO:0003924; GO:0005525; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0008156; GO:0008285; GO:0016020; GO:0022408; GO:0030336; GO:0031397; GO:0031965; GO:0033342; GO:0042273; GO:0048471; GO:0050821; GO:1990275 25393 XM_029357775.2 791 641 557 607 1050 O46606 3.19e-114 Phospholipase DDHD1 (EC 3.1.1.111) (EC 3.1.1.32) (DDHD domain-containing protein 1) (Phosphatidic acid-preferring phospholipase A1) (PA-PLA1) (EC 3.1.1.118) (Phospholipid sn-1 acylhydrolase) Bos taurus (Bovine) lipid metabolic process [GO:0006629] GO:0004620; GO:0005737; GO:0006629; GO:0008970; GO:0046872 25394 XM_044306749.1 30 14 43 19 39 NA NA NA NA NA NA 25395 XM_029345638.2 439 936 279 1478 839 Q9NVH0 8.73e-86 Exonuclease 3'-5' domain-containing protein 2 (EC 3.1.11.1) (3'-5' exoribonuclease EXD2) (EC 3.1.13.-) (Exonuclease 3'-5' domain-like-containing protein 2) Homo sapiens (Human) DNA double-strand break processing [GO:0000729]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; replication fork processing [GO:0031297] GO:0000175; GO:0000287; GO:0000724; GO:0000729; GO:0003676; GO:0005634; GO:0005737; GO:0005739; GO:0005741; GO:0005759; GO:0006302; GO:0008296; GO:0008310; GO:0008408; GO:0008852; GO:0030145; GO:0031297; GO:0042803; GO:0045111; GO:0090305; GO:0090734 25396 XM_029345638.2 439 936 279 1478 839 Q9NVH0 1.37e-30 Exonuclease 3'-5' domain-containing protein 2 (EC 3.1.11.1) (3'-5' exoribonuclease EXD2) (EC 3.1.13.-) (Exonuclease 3'-5' domain-like-containing protein 2) Homo sapiens (Human) DNA double-strand break processing [GO:0000729]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; replication fork processing [GO:0031297] GO:0000175; GO:0000287; GO:0000724; GO:0000729; GO:0003676; GO:0005634; GO:0005737; GO:0005739; GO:0005741; GO:0005759; GO:0006302; GO:0008296; GO:0008310; GO:0008408; GO:0008852; GO:0030145; GO:0031297; GO:0042803; GO:0045111; GO:0090305; GO:0090734 25397 XM_029326895.2 1891 1499 705 1640 1660 P70704 0 Phospholipid-transporting ATPase IA (EC 7.6.2.1) (ATPase class I type 8A member 1) (Chromaffin granule ATPase II) (P4-ATPase flippase complex alpha subunit ATP8A1) Mus musculus (Mouse) aminophospholipid translocation [GO:0140331]; learning [GO:0007612]; phospholipid translocation [GO:0045332]; positive regulation of cell migration [GO:0030335]; positive regulation of phospholipid translocation [GO:0061092] GO:0000287; GO:0005524; GO:0005783; GO:0005794; GO:0005802; GO:0005886; GO:0007612; GO:0016887; GO:0030335; GO:0030672; GO:0031090; GO:0031410; GO:0042584; GO:0043231; GO:0045202; GO:0045332; GO:0061092; GO:0090556; GO:0140326; GO:0140331; GO:0140346; GO:1990531 25398 XM_029326895.2 1891 1499 705 1640 1660 P70704 1.57e-42 Phospholipid-transporting ATPase IA (EC 7.6.2.1) (ATPase class I type 8A member 1) (Chromaffin granule ATPase II) (P4-ATPase flippase complex alpha subunit ATP8A1) Mus musculus (Mouse) aminophospholipid translocation [GO:0140331]; learning [GO:0007612]; phospholipid translocation [GO:0045332]; positive regulation of cell migration [GO:0030335]; positive regulation of phospholipid translocation [GO:0061092] GO:0000287; GO:0005524; GO:0005783; GO:0005794; GO:0005802; GO:0005886; GO:0007612; GO:0016887; GO:0030335; GO:0030672; GO:0031090; GO:0031410; GO:0042584; GO:0043231; GO:0045202; GO:0045332; GO:0061092; GO:0090556; GO:0140326; GO:0140331; GO:0140346; GO:1990531 25399 XM_044322310.1 25 0 7 2 0 NA NA NA NA NA NA 25400 XM_044317911.1 0 31 33 15 0 O15439 0 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 25401 XM_044314654.1 0 0 0 0 50 NA NA NA NA NA NA 25402 XM_044314158.1 56 10 0 81 11 NA NA NA NA NA NA 25403 XM_029357091.2 26 0 0 1 30 NA NA NA NA NA NA 25404 XM_029352023.2 712 306 514 858 494 Q8N983 3.01e-32 39S ribosomal protein L43, mitochondrial (L43mt) (MRP-L43) (Mitochondrial large ribosomal subunit protein mL43) (Mitochondrial ribosomal protein bMRP36a) Homo sapiens (Human) mitochondrial translation [GO:0032543]; translation [GO:0006412] GO:0003723; GO:0003735; GO:0005739; GO:0005743; GO:0005761; GO:0005762; GO:0006412; GO:0032543 25405 XM_029347382.2 854 770 191 995 945 Q8IV35 2.05e-86 WD repeat-containing protein 49 Homo sapiens (Human) NA NA 25406 XM_029345798.2 35 11 5 12 46 Q0DXS3 6.08e-137 Probable RNA-dependent RNA polymerase 1 (OsRDR1) (EC 2.7.7.48) Oryza sativa subsp. japonica (Rice) positive regulation of post-transcriptional gene silencing [GO:0060148]; response to salicylic acid [GO:0009751]; response to virus [GO:0009615]; siRNA processing [GO:0030422]; wax biosynthetic process [GO:0010025] GO:0003723; GO:0003968; GO:0009615; GO:0009751; GO:0010025; GO:0030422; GO:0031380; GO:0060148 25407 XM_029325988.2 1597 1027 1406 3336 2544 Q5U4T7 8.89e-152 Protein bicaudal C homolog 1-B (Bic-C-B) Xenopus laevis (African clawed frog) NA GO:0003723 25408 XM_029325988.2 1597 1027 1406 3336 2544 Q5U4T7 9.43e-34 Protein bicaudal C homolog 1-B (Bic-C-B) Xenopus laevis (African clawed frog) NA GO:0003723 25409 XR_006392976.1 41 2 25 5 151 NA NA NA NA NA NA 25410 XM_029349669.2 10 0 1 0 4 Q6BD04 1.29e-23 G-protein coupled receptor 54 Oreochromis niloticus (Nile tilapia) (Tilapia nilotica) NA GO:0004930; GO:0005886 25411 XM_029349163.2 308 140 147 173 341 Q90YB1 0 DNA ligase 4 (EC 6.5.1.1) (DNA ligase IV) (Polydeoxyribonucleotide synthase [ATP] 4) Gallus gallus (Chicken) cell cycle [GO:0007049]; cell division [GO:0051301]; DNA biosynthetic process [GO:0071897]; DNA ligation involved in DNA repair [GO:0051103]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; immunoglobulin V(D)J recombination [GO:0033152]; nucleotide-excision repair, DNA gap filling [GO:0006297] GO:0003677; GO:0003910; GO:0005524; GO:0005654; GO:0005958; GO:0006260; GO:0006297; GO:0006303; GO:0007049; GO:0032807; GO:0033152; GO:0046872; GO:0051103; GO:0051301; GO:0070419; GO:0071897 25412 XM_029334488.2 1701 1524 1062 1097 1871 A0A166YZY4 6.42e-35 2-oxoglutarate-Fe(II) type oxidoreductase ppzD (EC 1.14.11.-) (Pyrrolopyrazine biosynthesis cluster protein D) Metarhizium rileyi (strain RCEF 4871) (Nomuraea rileyi) organic acid biosynthetic process [GO:0016053]; organic cyclic compound biosynthetic process [GO:1901362] GO:0016053; GO:0046872; GO:0051213; GO:1901362 25413 XM_044308085.1 8 143 90 35 15 Q92113 4.01e-135 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Squalus acanthias (Spiny dogfish) steroid biosynthetic process [GO:0006694] GO:0004508; GO:0005506; GO:0006694; GO:0016020; GO:0020037; GO:0047442 25414 XM_044324652.1 9 4 0 4 0 NA NA NA NA NA NA 25415 XM_044312856.1 61 9 24 26 0 O88451 1.23e-82 Retinol dehydrogenase 7 (EC 1.1.1.105) (Cis-retinol/3alpha-hydroxysterol short-chain dehydrogenase isozyme 2) (Cis-retinol/androgen dehydrogenase type 2) (CRAD-2) Mus musculus (Mouse) retinol metabolic process [GO:0042572]; steroid metabolic process [GO:0008202] GO:0003824; GO:0004745; GO:0005783; GO:0008202; GO:0016491; GO:0042572; GO:0043231; GO:0047023; GO:0047044 25416 XM_029334789.2 70491 55347 36633 45033 21606 P26779 1.37e-46 Prosaposin (Proactivator polypeptide) [Cleaved into: Saposin-A (Protein A); Saposin-B (Cerebroside sulfate activator) (CSAct) (Dispersin) (Sphingolipid activator protein 1) (SAP-1) (Sulfatide/GM1 activator); Saposin-C (A1 activator) (Co-beta-glucosidase) (Glucosylceramidase activator) (Sphingolipid activator protein 2) (SAP-2); Saposin-D (Component C) (Protein C)] Bos taurus (Bovine) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; epithelial cell differentiation involved in prostate gland development [GO:0060742]; lysosomal transport [GO:0007041]; prostate gland growth [GO:0060736]; regulation of lipid metabolic process [GO:0019216]; sphingolipid metabolic process [GO:0006665] GO:0005576; GO:0005615; GO:0005764; GO:0005770; GO:0006665; GO:0007041; GO:0007193; GO:0019216; GO:0060736; GO:0060742 25417 XM_029334789.2 70491 55347 36633 45033 21606 P26779 2.73e-33 Prosaposin (Proactivator polypeptide) [Cleaved into: Saposin-A (Protein A); Saposin-B (Cerebroside sulfate activator) (CSAct) (Dispersin) (Sphingolipid activator protein 1) (SAP-1) (Sulfatide/GM1 activator); Saposin-C (A1 activator) (Co-beta-glucosidase) (Glucosylceramidase activator) (Sphingolipid activator protein 2) (SAP-2); Saposin-D (Component C) (Protein C)] Bos taurus (Bovine) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; epithelial cell differentiation involved in prostate gland development [GO:0060742]; lysosomal transport [GO:0007041]; prostate gland growth [GO:0060736]; regulation of lipid metabolic process [GO:0019216]; sphingolipid metabolic process [GO:0006665] GO:0005576; GO:0005615; GO:0005764; GO:0005770; GO:0006665; GO:0007041; GO:0007193; GO:0019216; GO:0060736; GO:0060742 25418 XM_029334789.2 70491 55347 36633 45033 21606 P26779 2.15e-26 Prosaposin (Proactivator polypeptide) [Cleaved into: Saposin-A (Protein A); Saposin-B (Cerebroside sulfate activator) (CSAct) (Dispersin) (Sphingolipid activator protein 1) (SAP-1) (Sulfatide/GM1 activator); Saposin-C (A1 activator) (Co-beta-glucosidase) (Glucosylceramidase activator) (Sphingolipid activator protein 2) (SAP-2); Saposin-D (Component C) (Protein C)] Bos taurus (Bovine) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; epithelial cell differentiation involved in prostate gland development [GO:0060742]; lysosomal transport [GO:0007041]; prostate gland growth [GO:0060736]; regulation of lipid metabolic process [GO:0019216]; sphingolipid metabolic process [GO:0006665] GO:0005576; GO:0005615; GO:0005764; GO:0005770; GO:0006665; GO:0007041; GO:0007193; GO:0019216; GO:0060736; GO:0060742 25419 XM_029344219.2 0 0 0 60 1 O95263 0 High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B (HsPDE8B) (EC 3.1.4.53) (Cell proliferation-inducing gene 22 protein) Homo sapiens (Human) behavioral fear response [GO:0001662]; cAMP catabolic process [GO:0006198]; negative regulation of steroid hormone biosynthetic process [GO:0090032]; neuromuscular process controlling balance [GO:0050885]; operant conditioning [GO:0035106]; signal transduction [GO:0007165]; visual learning [GO:0008542] GO:0001662; GO:0004114; GO:0004115; GO:0005829; GO:0006198; GO:0007165; GO:0008542; GO:0035106; GO:0046872; GO:0050885; GO:0090032 25420 XM_044326842.1 469 296 214 447 1273 Q4G0S4 1.39e-81 Cytochrome P450 27C1 (EC 1.14.19.53) (All-trans retinol 3,4-desaturase) Homo sapiens (Human) retinal metabolic process [GO:0042574]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572] GO:0001972; GO:0004497; GO:0005502; GO:0005503; GO:0005506; GO:0005739; GO:0020037; GO:0031966; GO:0042572; GO:0042573; GO:0042574; GO:0043231; GO:0061896; GO:0061897; GO:0061898; GO:0061899; GO:1904768 25421 XM_044311039.1 44 14 10 0 15 NA NA NA NA NA NA 25422 XM_029331457.2 224 255 221 319 227 Q6P1A2 2.32e-107 Lysophospholipid acyltransferase 5 (LPLAT 5) (EC 2.3.1.-) (1-acylglycerophosphocholine O-acyltransferase) (EC 2.3.1.23) (1-acylglycerophosphoethanolamine O-acyltransferase) (EC 2.3.1.n7) (1-acylglycerophosphoserine O-acyltransferase) (EC 2.3.1.n6) (Lysophosphatidylcholine acyltransferase) (LPCAT) (Lyso-PC acyltransferase) (Lysophosphatidylcholine acyltransferase 3) (Lyso-PC acyltransferase 3) (Lysophosphatidylserine acyltransferase) (LPSAT) (Lyso-PS acyltransferase) (Membrane-bound O-acyltransferase domain-containing protein 5) (O-acyltransferase domain-containing protein 5) Homo sapiens (Human) chylomicron assembly [GO:0034378]; endoplasmic reticulum membrane organization [GO:0090158]; intestinal stem cell homeostasis [GO:0036335]; lipid modification [GO:0030258]; negative regulation of inflammatory response [GO:0050728]; negative regulation of response to endoplasmic reticulum stress [GO:1903573]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylcholine biosynthetic process [GO:0006656]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; phosphatidylserine acyl-chain remodeling [GO:0036150]; positive regulation of intestinal cholesterol absorption [GO:0045797]; positive regulation of sterol regulatory element binding protein cleavage [GO:1901310]; positive regulation of triglyceride transport [GO:1905885]; regulation of cholesterol biosynthetic process [GO:0045540]; very-low-density lipoprotein particle assembly [GO:0034379] GO:0003841; GO:0005789; GO:0006656; GO:0016020; GO:0016746; GO:0030258; GO:0034378; GO:0034379; GO:0036150; GO:0036151; GO:0036152; GO:0036335; GO:0045540; GO:0045797; GO:0047144; GO:0047184; GO:0050728; GO:0071617; GO:0090158; GO:0106262; GO:0106263; GO:1901310; GO:1903573; GO:1905885 25423 XM_044321577.1 94 150 106 153 136 NA NA NA NA NA NA 25424 XR_006394440.1 252 341 122 426 62 NA NA NA NA NA NA 25425 XM_044322018.1 552 401 125 226 50 NA NA NA NA NA NA 25426 XM_044312672.1 1062 739 711 1644 985 Q8CGE9 4.4e-28 Regulator of G-protein signaling 12 (RGS12) Mus musculus (Mouse) regulation of G protein-coupled receptor signaling pathway [GO:0008277]; signal transduction [GO:0007165]; termination of G protein-coupled receptor signaling pathway [GO:0038032] GO:0001965; GO:0005096; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0005886; GO:0007165; GO:0008277; GO:0030425; GO:0030695; GO:0032991; GO:0038032; GO:0043025; GO:0045202; GO:0097440 25427 XM_044312672.1 1062 739 711 1644 985 Q8CGE9 7.03e-27 Regulator of G-protein signaling 12 (RGS12) Mus musculus (Mouse) regulation of G protein-coupled receptor signaling pathway [GO:0008277]; signal transduction [GO:0007165]; termination of G protein-coupled receptor signaling pathway [GO:0038032] GO:0001965; GO:0005096; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0005886; GO:0007165; GO:0008277; GO:0030425; GO:0030695; GO:0032991; GO:0038032; GO:0043025; GO:0045202; GO:0097440 25428 XM_029329050.2 460 373 281 301 597 NA NA NA NA NA NA 25429 XM_044327510.1 199 395 0 99 500 NA NA NA NA NA NA 25430 XM_029349770.2 26 0 4 0 0 NA NA NA NA NA NA 25431 XR_006391689.1 0 13 0 13 77 NA NA NA NA NA NA 25432 XM_029334269.2 2991 1432 967 1489 1119 Q6NU27 1.49e-69 Eukaryotic translation initiation factor 4E type 3-B (eIF-4E type 3-B) (eIF-4E3-B) (eIF4E type 3-B) (eIF4E-3-B) Xenopus laevis (African clawed frog) NA GO:0003723; GO:0003743; GO:0005845 25433 XM_044307713.1 224 138 123 23 104 NA NA NA NA NA NA 25434 XR_006395463.1 13 14 10 14 23 NA NA NA NA NA NA 25435 XM_029340554.2 5 2 7 2 11 NA NA NA NA NA NA 25436 XM_029350791.2 727 4948 2807 2691 251 Q9PUH5 8.21e-21 Basic phospholipase A2 S11-61 (svPLA2) (EC 3.1.1.4) (ASPLA9) (Phosphatidylcholine 2-acylhydrolase) Austrelaps superbus (Lowland copperhead snake) (Hoplocephalus superbus) arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644] GO:0004623; GO:0005509; GO:0005576; GO:0006644; GO:0016042; GO:0050482; GO:0090729 25437 XM_044322592.1 2 4 0 4 10 C6KFA3 3.86e-21 Adhesion G-protein coupled receptor G6 (G-protein coupled receptor 126) [Cleaved into: ADGRG6 N-terminal fragment (ADGRG6-NTF); ADGRG6 C-terminal fragment (ADGRG6-CTF)] Danio rerio (Zebrafish) (Brachydanio rerio) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cAMP-mediated signaling [GO:0019933]; cell surface receptor signaling pathway [GO:0007166]; ear development [GO:0043583]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; heart trabecula formation [GO:0060347]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; myelination of posterior lateral line nerve axons [GO:0048932]; ossification [GO:0001503]; peripheral nervous system myelin formation [GO:0032290]; regulation of sprouting angiogenesis [GO:1903670]; Schwann cell differentiation [GO:0014037]; semicircular canal fusion [GO:0060879] GO:0001503; GO:0004930; GO:0005518; GO:0005886; GO:0007005; GO:0007166; GO:0007186; GO:0007189; GO:0007507; GO:0014037; GO:0019933; GO:0022011; GO:0032290; GO:0042552; GO:0043236; GO:0043583; GO:0048932; GO:0050840; GO:0060347; GO:0060879; GO:1903670 25438 XM_029351992.2 1278 918 873 1285 1015 Q9TTW3 5.48e-94 Tektin-1 Canis lupus familiaris (Dog) (Canis familiaris) cilium movement involved in cell motility [GO:0060294] GO:0005879; GO:0031514; GO:0060294 25439 XR_003827241.2 90 96 45 294 164 NA NA NA NA NA NA 25440 XR_006398154.1 83 48 25 28 126 NA NA NA NA NA NA 25441 XM_044308187.1 0 55 0 0 0 Q9V9A7 2.48e-163 Probable methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCase subunit beta) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 2) (3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta) Drosophila melanogaster (Fruit fly) coenzyme A metabolic process [GO:0015936]; leucine catabolic process [GO:0006552]; regulation of eclosion [GO:0007563] GO:0004485; GO:0005524; GO:0005739; GO:0005759; GO:0006552; GO:0007563; GO:0015936; GO:1905202 25442 XM_044315849.1 49 110 48 48 51 Q96AY4 9.26e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25443 XM_029333977.2 41 32 9 87 87 NA NA NA NA NA NA 25444 XM_044323876.1 153 12 20 25 160 NA NA NA NA NA NA 25445 XM_044311606.1 29 7 0 0 0 NA NA NA NA NA NA 25446 XM_044325186.1 259 615 339 822 220 NA NA NA NA NA NA 25447 XM_029349475.2 532 641 350 545 452 Q68EL3 2.78e-22 BET1-like protein Danio rerio (Zebrafish) (Brachydanio rerio) protein transport [GO:0015031]; regulation of retrograde vesicle-mediated transport, Golgi to ER [GO:2000156]; retrograde transport, endosome to Golgi [GO:0042147] GO:0000138; GO:0000139; GO:0005484; GO:0005829; GO:0015031; GO:0031201; GO:0042147; GO:2000156 25448 XM_044319668.1 8 5 1 8 2 P30974 1.02e-33 Tachykinin-like peptides receptor 86C (NKD) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; inter-male aggressive behavior [GO:0002121]; neuropeptide signaling pathway [GO:0007218]; tachykinin receptor signaling pathway [GO:0007217] GO:0002121; GO:0004995; GO:0005886; GO:0007186; GO:0007217; GO:0007218; GO:0008188; GO:0016020 25449 XM_029331861.2 123 111 127 184 115 NA NA NA NA NA NA 25450 XM_029335940.2 116 57 31 55 114 Q6DGP7 1.3e-33 LYR motif containing protein 1 Danio rerio (Zebrafish) (Brachydanio rerio) NA NA 25451 XM_044306780.1 43 22 269 78 69 NA NA NA NA NA NA 25452 XM_029355629.2 0 3 5 11 4 NA NA NA NA NA NA 25453 XM_029343732.2 88 134 85 120 49 NA NA NA NA NA NA 25454 XM_029349283.2 45 25 67 121 18 P57788 1.83e-41 Monocarboxylate transporter 4 (MCT 4) (Solute carrier family 16 member 3) Gallus gallus (Chicken) lactate transmembrane transport [GO:0035873]; pyruvate transmembrane transport [GO:1901475] GO:0005886; GO:0015650; GO:0016323; GO:0035873; GO:0050833; GO:1901475 25455 XM_044325369.1 0 11 9 0 20 NA NA NA NA NA NA 25456 XM_029331771.2 182 0 96 0 0 Q9R1A8 0 E3 ubiquitin-protein ligase COP1 (EC 2.3.2.27) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1) (RING finger and WD repeat domain protein 2) (RING-type E3 ubiquitin transferase RFWD2) Mus musculus (Mouse) positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; response to ionizing radiation [GO:0010212] GO:0000139; GO:0010212; GO:0016607; GO:0031464; GO:0032436; GO:0043161; GO:0046872; GO:0061630 25457 XM_044324590.1 0 0 0 32 24 NA NA NA NA NA NA 25458 XM_029341189.2 81 0 0 7 33 Q91175 8.59e-43 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (MAR1) Oryzias latipes (Japanese rice fish) (Japanese killifish) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of vasoconstriction [GO:0045907] GO:0001996; GO:0004930; GO:0004937; GO:0005886; GO:0007200; GO:0007204; GO:0007267; GO:0043410; GO:0045907; GO:0071880 25459 XR_006396761.1 33 134 31 39 87 NA NA NA NA NA NA 25460 XM_029352433.2 1028 1090 590 687 787 Q8HYI9 9.6e-40 Prefoldin subunit 5 Bos taurus (Bovine) negative regulation of amyloid fibril formation [GO:1905907]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of DNA-templated transcription [GO:0045892]; protein folding [GO:0006457]; retina development in camera-type eye [GO:0060041] GO:0001540; GO:0005634; GO:0005737; GO:0005829; GO:0006457; GO:0016272; GO:0045111; GO:0045892; GO:0051082; GO:0060041; GO:0090090; GO:1905907 25461 XM_029342412.2 139 288 0 176 8 P16157 4.25e-94 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 25462 XM_029342412.2 139 288 0 176 8 P16157 8.37e-87 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 25463 XM_029342412.2 139 288 0 176 8 P16157 6.23e-86 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 25464 XM_044323982.1 18 0 149 163 18 P35546 4.85e-81 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; anatomical structure morphogenesis [GO:0009653]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006919; GO:0007156; GO:0007158; GO:0007169; GO:0007399; GO:0009410; GO:0009653; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030182; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0098797; GO:2001241 25465 XM_044327648.1 1 0 68 97 0 Q96AY4 8.55e-108 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25466 XM_044327648.1 1 0 68 97 0 Q96AY4 3.89e-81 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25467 XM_044327648.1 1 0 68 97 0 Q96AY4 8.86e-72 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25468 XM_044327648.1 1 0 68 97 0 Q96AY4 4.89e-63 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25469 XM_044327648.1 1 0 68 97 0 Q96AY4 1.67e-60 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25470 XM_044323547.1 16 11 10 27 54 NA NA NA NA NA NA 25471 XM_044320438.1 641 307 377 448 638 A7RRZ8 6.86e-129 ATP-dependent (S)-NAD(P)H-hydrate dehydratase (EC 4.2.1.93) (ATP-dependent NAD(P)HX dehydratase) Nematostella vectensis (Starlet sea anemone) metabolite repair [GO:0110051]; nicotinamide nucleotide metabolic process [GO:0046496] GO:0005524; GO:0046496; GO:0047453; GO:0110051 25472 XM_044310625.1 0 0 6 0 3 NA NA NA NA NA NA 25473 XM_044313160.1 22 11 0 24 9 O02824 5.05e-32 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) Oryctolagus cuniculus (Rabbit) adult heart development [GO:0007512]; cell growth involved in cardiac muscle cell development [GO:0061049]; MAPK cascade [GO:0000165]; multicellular organism aging [GO:0010259]; negative regulation of autophagy [GO:0010507]; negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure [GO:0001985]; neuron-glial cell signaling [GO:0150099]; norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001994]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; pilomotor reflex [GO:0097195]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of the force of heart contraction by epinephrine-norepinephrine [GO:0001997]; regulation of cardiac muscle contraction [GO:0055117]; regulation of vasoconstriction [GO:0019229] GO:0000165; GO:0001985; GO:0001994; GO:0001996; GO:0001997; GO:0004937; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0005901; GO:0007200; GO:0007512; GO:0010259; GO:0010507; GO:0010613; GO:0019229; GO:0031965; GO:0043410; GO:0045987; GO:0046982; GO:0055117; GO:0061049; GO:0097195; GO:0150099; GO:1903997 25474 XM_044311575.1 3 1 4 24 28 P34992 3.1e-26 Neuropeptide Y receptor type 1 (NPY1-R) Xenopus laevis (African clawed frog) NA GO:0004983; GO:0005886 25475 XM_029357890.2 130 54 60 119 161 O15974 1.82e-30 Rhodopsin, G0-coupled (G0-rhodopsin) Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis) phototransduction [GO:0007602]; visual perception [GO:0007601] GO:0004930; GO:0005886; GO:0007601; GO:0007602; GO:0009881 25476 XM_044316841.1 878 258 107 247 490 NA NA NA NA NA NA 25477 XM_029337970.2 30 176 0 2012 202 O00339 1.31e-49 Matrilin-2 Homo sapiens (Human) extracellular matrix organization [GO:0030198] GO:0005201; GO:0005509; GO:0005576; GO:0030198; GO:0031012; GO:0062023; GO:0120216 25478 XM_029337970.2 30 176 0 2012 202 O00339 8.81e-40 Matrilin-2 Homo sapiens (Human) extracellular matrix organization [GO:0030198] GO:0005201; GO:0005509; GO:0005576; GO:0030198; GO:0031012; GO:0062023; GO:0120216 25479 XM_029337970.2 30 176 0 2012 202 O00339 7.65e-31 Matrilin-2 Homo sapiens (Human) extracellular matrix organization [GO:0030198] GO:0005201; GO:0005509; GO:0005576; GO:0030198; GO:0031012; GO:0062023; GO:0120216 25480 XM_029337970.2 30 176 0 2012 202 O00339 1.24e-30 Matrilin-2 Homo sapiens (Human) extracellular matrix organization [GO:0030198] GO:0005201; GO:0005509; GO:0005576; GO:0030198; GO:0031012; GO:0062023; GO:0120216 25481 XM_029337970.2 30 176 0 2012 202 O00339 3.56e-30 Matrilin-2 Homo sapiens (Human) extracellular matrix organization [GO:0030198] GO:0005201; GO:0005509; GO:0005576; GO:0030198; GO:0031012; GO:0062023; GO:0120216 25482 XM_029337970.2 30 176 0 2012 202 O00339 2.87e-22 Matrilin-2 Homo sapiens (Human) extracellular matrix organization [GO:0030198] GO:0005201; GO:0005509; GO:0005576; GO:0030198; GO:0031012; GO:0062023; GO:0120216 25483 XM_029347932.2 9 5 4 9 63 NA NA NA NA NA NA 25484 XM_044308833.1 3 13 12 4 13 NA NA NA NA NA NA 25485 XM_029335706.2 331 452 118 287 239 Q1KZG4 3.21e-52 Bis(5'-adenosyl)-triphosphatase (EC 3.6.1.29) (AP3A hydrolase) (AP3Aase) (Adenosine 5'-monophosphoramidase FHIT) (EC 3.9.1.-) (Adenylylsulfatase) (EC 3.6.2.1) (Adenylylsulfate-ammonia adenylyltransferase) (EC 2.7.7.51) (Diadenosine 5',5'''-P1,P3-triphosphate hydrolase) (Dinucleosidetriphosphatase) (Fragile histidine triad protein) Bos taurus (Bovine) diadenosine triphosphate catabolic process [GO:0015964]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; purine nucleotide metabolic process [GO:0006163] GO:0000166; GO:0001650; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0005886; GO:0006163; GO:0015964; GO:0031625; GO:0032435; GO:0042802; GO:0043530; GO:0047352; GO:0047627; GO:0047710; GO:0072332 25486 XM_029355602.2 25 6 2 4 23 P49219 1.52e-26 Melatonin receptor type 1C (Mel-1C-R) (Mel1c (alpha) receptor) (Mel1c receptor) Xenopus laevis (African clawed frog) NA GO:0005886; GO:0008502 25487 XM_029351036.2 606 799 541 990 1125 Q9CPZ8 1.52e-27 COX assembly mitochondrial protein homolog (Cmc1p) Mus musculus (Mouse) NA GO:0005739; GO:0046872 25488 XM_044320892.1 0 7 1 2 1 NA NA NA NA NA NA 25489 XM_044312185.1 31 15 61 45 155 NA NA NA NA NA NA 25490 XM_029342025.2 241 694 372 810 569 NA NA NA NA NA NA 25491 XM_029334886.2 0 0 12 0 0 O42574 5.93e-24 Beta-1 adrenergic receptor (Beta-1 adrenoreceptor) (Beta-1 adrenoceptor) (x-BETA1AR) Xenopus laevis (African clawed frog) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; positive regulation of GTPase activity [GO:0043547]; positive regulation of heart contraction [GO:0045823] GO:0004940; GO:0005085; GO:0005769; GO:0005886; GO:0043547; GO:0045823; GO:0071880 25492 XR_006394863.1 0 60 0 18 97 NA NA NA NA NA NA 25493 XM_044321553.1 126 103 50 54 102 Q5ZIL9 2.47e-154 KIF-binding protein (KIF1-binding protein) Gallus gallus (Chicken) central nervous system projection neuron axonogenesis [GO:0021952]; microtubule cytoskeleton organization [GO:0000226]; mitochondrial transport [GO:0006839]; neuron projection maintenance [GO:1990535] GO:0000226; GO:0005739; GO:0005856; GO:0006839; GO:0019894; GO:0021952; GO:1990535 25494 XM_029343563.2 156 97 33 172 180 NA NA NA NA NA NA 25495 XR_006396176.1 197 68 106 139 323 Q5DU56 1.42e-25 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 25496 XR_006396176.1 197 68 106 139 323 Q5DU56 1.72e-25 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 25497 XR_006393972.1 13 14 25 63 36 NA NA NA NA NA NA 25498 XM_029334147.2 1763 1338 873 1482 465 E7EY42 8.44e-173 Phosphatidylserine synthase 2 (PSS-2) (PtdSer synthase 2) (EC 2.7.8.29) (Serine-exchange enzyme II) Danio rerio (Zebrafish) (Brachydanio rerio) phosphatidylserine biosynthetic process [GO:0006659] GO:0005789; GO:0006659; GO:0106245 25499 XM_029337848.2 44 0 0 0 156 NA NA NA NA NA NA 25500 XM_029336492.2 428 126 141 366 270 NA NA NA NA NA NA 25501 XM_044311376.1 133 79 89 216 96 C6FG12 7.78e-26 Protein NLRC5 Ictalurus punctatus (Channel catfish) (Silurus punctatus) innate immune response [GO:0045087] GO:0005524; GO:0005737; GO:0045087 25502 XM_029327490.2 767 591 334 335 514 NA NA NA NA NA NA 25503 XR_006393938.1 0 0 7 0 0 NA NA NA NA NA NA 25504 XR_006391489.1 94 91 48 91 49 NA NA NA NA NA NA 25505 XM_044315841.1 121 80 149 165 133 B8V7S0 4.27e-63 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 25506 XR_003826464.2 510 2434 485 441 1237 NA NA NA NA NA NA 25507 XM_029328836.2 987 612 387 919 544 NA NA NA NA NA NA 25508 XM_044308023.1 147 187 139 292 304 Q8BG58 9.78e-58 Transmembrane prolyl 4-hydroxylase (P4H-TM) (EC 1.14.11.29) (Hypoxia-inducible factor prolyl hydroxylase 4) (HIF-PH4) (HIF-prolyl hydroxylase 4) (HPH-4) Mus musculus (Mouse) peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; regulation of erythrocyte differentiation [GO:0045646] GO:0004656; GO:0005506; GO:0005509; GO:0005783; GO:0005789; GO:0016706; GO:0018401; GO:0031418; GO:0045646 25509 XM_044308023.1 147 187 139 292 304 Q8BG58 4.4e-56 Transmembrane prolyl 4-hydroxylase (P4H-TM) (EC 1.14.11.29) (Hypoxia-inducible factor prolyl hydroxylase 4) (HIF-PH4) (HIF-prolyl hydroxylase 4) (HPH-4) Mus musculus (Mouse) peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; regulation of erythrocyte differentiation [GO:0045646] GO:0004656; GO:0005506; GO:0005509; GO:0005783; GO:0005789; GO:0016706; GO:0018401; GO:0031418; GO:0045646 25510 XR_006393747.1 227 138 152 166 243 Q9CXB8 1.8e-41 Alpha-protein kinase 1 (EC 2.7.11.1) Mus musculus (Mouse) cilium assembly [GO:0060271]; cytosolic pattern recognition receptor signaling pathway [GO:0002753]; innate immune response [GO:0045087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein phosphorylation [GO:0006468]; response to bacterium [GO:0009617] GO:0000922; GO:0002753; GO:0004674; GO:0005524; GO:0005813; GO:0005829; GO:0005929; GO:0006468; GO:0009617; GO:0032391; GO:0043123; GO:0045087; GO:0048029; GO:0060271; GO:0106310 25511 XM_044318942.1 1876 2624 793 1558 10316 Q58A42 2.29e-73 Protein DD3-3 Dictyostelium discoideum (Social amoeba) NA GO:0016020 25512 XM_029351616.2 1060 824 377 542 496 Q8K0H5 1.37e-46 Transcription initiation factor TFIID subunit 10 (Transcription initiation factor TFIID 30 kDa subunit) (TAF(II)30) (TAFII-30) (TAFII30) (mTAFII30) Mus musculus (Mouse) allantois development [GO:1905069]; apoptotic process [GO:0006915]; DNA-templated transcription initiation [GO:0006352]; embryonic placenta development [GO:0001892]; G1/S transition of mitotic cell cycle [GO:0000082]; gene expression [GO:0010467]; hepatocyte differentiation [GO:0070365]; histone acetylation [GO:0016573]; histone H3 acetylation [GO:0043966]; in utero embryonic development [GO:0001701]; lateral mesodermal cell differentiation [GO:0048371]; limb development [GO:0060173]; liver development [GO:0001889]; monoubiquitinated histone deubiquitination [GO:0035521]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; mRNA transcription by RNA polymerase II [GO:0042789]; multicellular organism growth [GO:0035264]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; protein phosphorylation [GO:0006468]; protein-containing complex assembly [GO:0065003]; regulation of DNA binding [GO:0051101]; regulation of DNA repair [GO:0006282]; regulation of DNA-templated transcription [GO:0006355]; regulation of gene expression [GO:0010468]; regulation of RNA splicing [GO:0043484]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA polymerase II preinitiation complex assembly [GO:0051123]; SAGA complex assembly [GO:0036285]; somitogenesis [GO:0001756]; transcription initiation at RNA polymerase II promoter [GO:0006367] GO:0000082; GO:0000124; GO:0001673; GO:0001701; GO:0001756; GO:0001889; GO:0001892; GO:0003677; GO:0004402; GO:0005634; GO:0005654; GO:0005669; GO:0005737; GO:0006282; GO:0006352; GO:0006355; GO:0006357; GO:0006367; GO:0006468; GO:0006915; GO:0010467; GO:0010468; GO:0016251; GO:0016573; GO:0019899; GO:0030331; GO:0033276; GO:0035264; GO:0035521; GO:0035522; GO:0036285; GO:0042789; GO:0042802; GO:0043484; GO:0043966; GO:0045893; GO:0048371; GO:0048471; GO:0051101; GO:0051123; GO:0060173; GO:0060261; GO:0065003; GO:0070063; GO:0070365; GO:0097550; GO:1905069; GO:1990841 25513 XM_029349764.2 9 21 29 0 1 NA NA NA NA NA NA 25514 XM_044314063.1 198 24 102 68 267 NA NA NA NA NA NA 25515 XR_006393198.1 125 11 44 24 76 NA NA NA NA NA NA 25516 XM_029353938.2 0 0 66 0 2 D3Z5L6 2.83e-48 MFS-type transporter SLC18B1 (Solute carrier family 18 member B1) (Vesicular polyamine transporter) (VPAT) Mus musculus (Mouse) serotonin transport [GO:0006837]; serotonin uptake [GO:0051610]; spermidine transport [GO:0015848]; spermine transport [GO:0000296] GO:0000296; GO:0006837; GO:0015311; GO:0015312; GO:0015848; GO:0022857; GO:0030667; GO:0030672; GO:0051610 25517 XM_029328255.2 282 377 355 382 369 NA NA NA NA NA NA 25518 XM_029333675.2 5913 7302 4451 3432 2547 Q6NYT1 3.01e-46 Mediator of RNA polymerase II transcription subunit 8 (Mediator complex subunit 8) Danio rerio (Zebrafish) (Brachydanio rerio) protein ubiquitination [GO:0016567]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0003712; GO:0006357; GO:0016567; GO:0016592; GO:0070847 25519 XM_029338658.2 5033 5552 2892 6448 6210 Q9CQN6 1.07e-29 Transmembrane protein 14C Mus musculus (Mouse) erythrocyte differentiation [GO:0030218]; heme biosynthetic process [GO:0006783]; mitochondrial transport [GO:0006839]; nitrogen compound transport [GO:0071705]; organic substance transport [GO:0071702]; regulation of heme biosynthetic process [GO:0070453] GO:0005739; GO:0005743; GO:0006783; GO:0006839; GO:0030218; GO:0031966; GO:0042802; GO:0070453; GO:0071702; GO:0071705 25520 XM_029329623.2 279 96 102 364 268 Q61503 4.45e-141 5'-nucleotidase (5'-NT) (EC 3.1.3.35) (EC 3.1.3.5) (EC 3.1.3.89) (EC 3.1.3.91) (EC 3.1.3.99) (5'-deoxynucleotidase) (Ecto-5'-nucleotidase) (IMP-specific 5'-nucleotidase) (Thymidylate 5'-phosphatase) (CD antigen CD73) Mus musculus (Mouse) adenosine biosynthetic process [GO:0046086]; adenosine metabolic process [GO:0046085]; ADP catabolic process [GO:0046032]; AMP catabolic process [GO:0006196]; ATP metabolic process [GO:0046034]; calcium ion homeostasis [GO:0055074]; leukocyte cell-cell adhesion [GO:0007159]; negative regulation of inflammatory response [GO:0050728]; response to ATP [GO:0033198]; response to inorganic substance [GO:0010035] GO:0000166; GO:0002953; GO:0005654; GO:0005829; GO:0005886; GO:0006196; GO:0007159; GO:0008198; GO:0008253; GO:0008270; GO:0009897; GO:0009986; GO:0010035; GO:0016020; GO:0033198; GO:0042802; GO:0046032; GO:0046034; GO:0046085; GO:0046086; GO:0050340; GO:0050483; GO:0050484; GO:0050728; GO:0055074; GO:0097060; GO:0106411 25521 XM_029329384.2 32437 36788 20041 35008 25353 NA NA NA NA NA NA 25522 XM_029323864.2 123 0 0 0 0 NA NA NA NA NA NA 25523 XM_029329142.2 11 5 7 13 20 P97292 1.7e-33 Histamine H2 receptor (H2R) (HH2R) (Gastric receptor I) Mus musculus (Mouse) chemical synaptic transmission [GO:0007268]; digestive tract development [GO:0048565]; epithelial cell morphogenesis [GO:0003382]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; gastric acid secretion [GO:0001696]; gastrin-induced gastric acid secretion [GO:0001698]; gland development [GO:0048732]; histamine-induced gastric acid secretion [GO:0001697]; memory [GO:0007613]; negative regulation of arachidonic acid secretion [GO:1900139]; positive regulation of vasoconstriction [GO:0045907]; regulation of synaptic plasticity [GO:0048167]; toxin transport [GO:1901998]; visual learning [GO:0008542] GO:0001696; GO:0001697; GO:0001698; GO:0003382; GO:0004969; GO:0004993; GO:0005886; GO:0007187; GO:0007268; GO:0007613; GO:0008542; GO:0016020; GO:0030425; GO:0030594; GO:0045202; GO:0045907; GO:0048167; GO:0048565; GO:0048732; GO:1900139; GO:1901363; GO:1901998 25524 XM_029342353.2 376 1051 888 2209 300 P98156 6.09e-158 Very low-density lipoprotein receptor (VLDL receptor) (VLDL-R) Mus musculus (Mouse) cellular response to hypoxia [GO:0071456]; cholesterol metabolic process [GO:0008203]; dendrite morphogenesis [GO:0048813]; glycoprotein transport [GO:0034436]; lipid transport [GO:0006869]; positive regulation of dendrite development [GO:1900006]; positive regulation of protein kinase activity [GO:0045860]; receptor-mediated endocytosis [GO:0006898]; reelin-mediated signaling pathway [GO:0038026]; ventral spinal cord development [GO:0021517]; very-low-density lipoprotein particle clearance [GO:0034447] GO:0005509; GO:0005615; GO:0005634; GO:0005886; GO:0005905; GO:0006869; GO:0006898; GO:0008203; GO:0009986; GO:0016020; GO:0021517; GO:0030229; GO:0034185; GO:0034189; GO:0034361; GO:0034436; GO:0034447; GO:0038024; GO:0038025; GO:0038026; GO:0043235; GO:0045177; GO:0045860; GO:0048306; GO:0048471; GO:0048813; GO:0071456; GO:1900006 25525 XM_029339144.2 72 106 48 13 122 NA NA NA NA NA NA 25526 XM_044327076.1 765 768 632 1000 1163 Q5ZJH6 5.12e-150 Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3) Gallus gallus (Chicken) autophagosome organization [GO:1905037]; negative regulation of smoothened signaling pathway [GO:0045879]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of smoothened signaling pathway [GO:0045880]; protein autophosphorylation [GO:0046777] GO:0000407; GO:0004674; GO:0005524; GO:0005737; GO:0005776; GO:0018105; GO:0045879; GO:0045880; GO:0046777; GO:0106310; GO:1905037 25527 XM_029335956.2 45 6 3 25 22 NA NA NA NA NA NA 25528 XM_044326018.1 0 52 7 88 112 Q9UKV8 0 Protein argonaute-2 (Argonaute2) (hAgo2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (PAZ Piwi domain protein) (PPD) (Protein slicer) Homo sapiens (Human) miRNA metabolic process [GO:0010586]; miRNA processing [GO:0035196]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; miRNA-mediated gene silencing by mRNA destabilization [GO:0035279]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; negative regulation of translational initiation [GO:0045947]; positive regulation of angiogenesis [GO:0045766]; positive regulation of gene expression [GO:0010628]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of trophoblast cell migration [GO:1901165]; post-embryonic development [GO:0009791]; pre-miRNA processing [GO:0031054]; RISC complex assembly [GO:0070922]; RNA secondary structure unwinding [GO:0010501]; RNA-mediated gene silencing [GO:0031047]; RNA-mediated post-transcriptional gene silencing [GO:0035194]; siRNA processing [GO:0030422]; siRNA-mediated gene silencing by mRNA destabilization [GO:0090625]; translation [GO:0006412] GO:0000340; GO:0000932; GO:0000993; GO:0001046; GO:0003723; GO:0003725; GO:0003727; GO:0003743; GO:0004521; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005844; GO:0005845; GO:0006412; GO:0008022; GO:0009791; GO:0010501; GO:0010586; GO:0010628; GO:0016020; GO:0016442; GO:0030422; GO:0030425; GO:0031047; GO:0031054; GO:0035194; GO:0035196; GO:0035197; GO:0035198; GO:0035278; GO:0035279; GO:0036464; GO:0042985; GO:0045766; GO:0045944; GO:0045947; GO:0046872; GO:0060213; GO:0070062; GO:0070551; GO:0070578; GO:0070922; GO:0090624; GO:0090625; GO:0098808; GO:1900153; GO:1901165; GO:1990904 25529 XM_029348696.2 406 234 181 161 232 NA NA NA NA NA NA 25530 XM_029341769.2 10 0 0 7 0 NA NA NA NA NA NA 25531 XM_029328991.2 24 0 3 3 0 NA NA NA NA NA NA 25532 XM_029348879.2 1651 2002 1152 898 1731 Q8BJT9 0 ER degradation-enhancing alpha-mannosidase-like protein 2 Mus musculus (Mouse) carbohydrate metabolic process [GO:0005975]; endoplasmic reticulum mannose trimming [GO:1904380]; mannose trimming involved in glycoprotein ERAD pathway [GO:1904382]; positive regulation of retrograde protein transport, ER to cytosol [GO:1904154]; response to unfolded protein [GO:0006986]; trimming of terminal mannose on B branch [GO:0036509]; ubiquitin-dependent glycoprotein ERAD pathway [GO:0097466] GO:0004571; GO:0005509; GO:0005783; GO:0005788; GO:0005975; GO:0006986; GO:0016020; GO:0036509; GO:0044322; GO:0097466; GO:1904154; GO:1904380; GO:1904382 25533 XM_029351428.2 1568 878 954 838 410 P40757 5.05e-147 Allantoinase, mitochondrial (EC 3.5.2.5) Lithobates catesbeianus (American bullfrog) (Rana catesbeiana) allantoin catabolic process [GO:0000256] GO:0000256; GO:0004038; GO:0005739; GO:0008270; GO:0050897 25534 XM_044309344.1 16 1 11 0 103 NA NA NA NA NA NA 25535 XR_006396915.1 653 267 559 883 972 Q9DBN1 1.74e-23 Stimulated by retinoic acid gene 6 protein-like (STRA6-like protein) (Retinol-binding protein 4 receptor 2) (RBP4 receptor 2) Mus musculus (Mouse) establishment of localization in cell [GO:0051649]; retinol transport [GO:0034633]; vitamin A import into cell [GO:0071939] GO:0005886; GO:0034633; GO:0051649; GO:0071939 25536 XM_044317752.1 341 0 0 0 0 P53667 3.42e-111 LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; axon extension [GO:0048675]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; nervous system development [GO:0007399]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of axon extension [GO:0045773]; positive regulation of stress fiber assembly [GO:0051496]; protein phosphorylation [GO:0006468]; Rho protein signal transduction [GO:0007266]; signal transduction [GO:0007165]; stress fiber assembly [GO:0043149] GO:0001673; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0005856; GO:0005925; GO:0006468; GO:0007165; GO:0007266; GO:0007399; GO:0016020; GO:0016607; GO:0030027; GO:0030036; GO:0031072; GO:0032233; GO:0038096; GO:0043005; GO:0043149; GO:0045773; GO:0046872; GO:0048675; GO:0051444; GO:0051496; GO:0106310 25537 XM_044314764.1 5 6 11 0 19 Q3UQ28 3.36e-22 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 25538 XM_029350121.2 19680 17593 5756 18868 8808 NA NA NA NA NA NA 25539 XR_003827205.2 55 20 4 6 378 NA NA NA NA NA NA 25540 XM_044320461.1 919 430 684 920 668 Q04656 0 Copper-transporting ATPase 1 (EC 7.2.2.8) (Copper pump 1) (Menkes disease-associated protein) Homo sapiens (Human) blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cartilage development [GO:0051216]; catecholamine metabolic process [GO:0006584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amino acid stimulus [GO:0071230]; cellular response to antibiotic [GO:0071236]; cellular response to cadmium ion [GO:0071276]; cellular response to cobalt ion [GO:0071279]; cellular response to copper ion [GO:0071280]; cellular response to hypoxia [GO:0071456]; cellular response to iron ion [GO:0071281]; cellular response to lead ion [GO:0071284]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; central nervous system neuron development [GO:0021954]; cerebellar Purkinje cell differentiation [GO:0021702]; collagen fibril organization [GO:0030199]; copper ion export [GO:0060003]; copper ion homeostasis [GO:0055070]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; detoxification of copper ion [GO:0010273]; dopamine metabolic process [GO:0042417]; elastic fiber assembly [GO:0048251]; elastin biosynthetic process [GO:0051542]; epinephrine metabolic process [GO:0042414]; extracellular matrix organization [GO:0030198]; female pregnancy [GO:0007565]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; lactation [GO:0007595]; liver development [GO:0001889]; locomotory behavior [GO:0007626]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; negative regulation of iron ion transmembrane transport [GO:0034760]; neuron projection morphogenesis [GO:0048812]; norepinephrine metabolic process [GO:0042415]; peptidyl-lysine modification [GO:0018205]; pigmentation [GO:0043473]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell size [GO:0045793]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of response to wounding [GO:1903036]; positive regulation of tyrosinase activity [GO:0032773]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; pyramidal neuron development [GO:0021860]; regulation of cytochrome-c oxidase activity [GO:1904959]; regulation of gene expression [GO:0010468]; regulation of oxidative phosphorylation [GO:0002082]; removal of superoxide radicals [GO:0019430]; response to iron(III) ion [GO:0010041]; response to manganese ion [GO:0010042]; response to zinc ion [GO:0010043]; serotonin metabolic process [GO:0042428]; skin development [GO:0043588]; T-helper cell differentiation [GO:0042093]; tryptophan metabolic process [GO:0006568] GO:0001568; GO:0001701; GO:0001889; GO:0001974; GO:0002082; GO:0005375; GO:0005507; GO:0005524; GO:0005634; GO:0005770; GO:0005783; GO:0005794; GO:0005802; GO:0005829; GO:0005886; GO:0005902; GO:0006568; GO:0006584; GO:0006825; GO:0006878; GO:0007005; GO:0007565; GO:0007595; GO:0007626; GO:0010041; GO:0010042; GO:0010043; GO:0010273; GO:0010468; GO:0010592; GO:0014069; GO:0015677; GO:0016020; GO:0016323; GO:0016324; GO:0016532; GO:0016887; GO:0018205; GO:0019430; GO:0021702; GO:0021860; GO:0021954; GO:0030140; GO:0030141; GO:0030198; GO:0030199; GO:0030424; GO:0030425; GO:0030670; GO:0031069; GO:0031252; GO:0031267; GO:0031526; GO:0031901; GO:0032588; GO:0032767; GO:0032773; GO:0033162; GO:0034760; GO:0036120; GO:0042093; GO:0042414; GO:0042415; GO:0042417; GO:0042428; GO:0043005; GO:0043025; GO:0043085; GO:0043204; GO:0043473; GO:0043588; GO:0043682; GO:0045121; GO:0045793; GO:0048023; GO:0048251; GO:0048286; GO:0048471; GO:0048812; GO:0050679; GO:0051087; GO:0051216; GO:0051542; GO:0055070; GO:0060003; GO:0071230; GO:0071236; GO:0071276; GO:0071279; GO:0071280; GO:0071281; GO:0071284; GO:0071456; GO:0140581; GO:1903036; GO:1903136; GO:1904754; GO:1904959 25541 XM_044320461.1 919 430 684 920 668 Q04656 1.47e-47 Copper-transporting ATPase 1 (EC 7.2.2.8) (Copper pump 1) (Menkes disease-associated protein) Homo sapiens (Human) blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cartilage development [GO:0051216]; catecholamine metabolic process [GO:0006584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amino acid stimulus [GO:0071230]; cellular response to antibiotic [GO:0071236]; cellular response to cadmium ion [GO:0071276]; cellular response to cobalt ion [GO:0071279]; cellular response to copper ion [GO:0071280]; cellular response to hypoxia [GO:0071456]; cellular response to iron ion [GO:0071281]; cellular response to lead ion [GO:0071284]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; central nervous system neuron development [GO:0021954]; cerebellar Purkinje cell differentiation [GO:0021702]; collagen fibril organization [GO:0030199]; copper ion export [GO:0060003]; copper ion homeostasis [GO:0055070]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; detoxification of copper ion [GO:0010273]; dopamine metabolic process [GO:0042417]; elastic fiber assembly [GO:0048251]; elastin biosynthetic process [GO:0051542]; epinephrine metabolic process [GO:0042414]; extracellular matrix organization [GO:0030198]; female pregnancy [GO:0007565]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; lactation [GO:0007595]; liver development [GO:0001889]; locomotory behavior [GO:0007626]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; negative regulation of iron ion transmembrane transport [GO:0034760]; neuron projection morphogenesis [GO:0048812]; norepinephrine metabolic process [GO:0042415]; peptidyl-lysine modification [GO:0018205]; pigmentation [GO:0043473]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell size [GO:0045793]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of response to wounding [GO:1903036]; positive regulation of tyrosinase activity [GO:0032773]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; pyramidal neuron development [GO:0021860]; regulation of cytochrome-c oxidase activity [GO:1904959]; regulation of gene expression [GO:0010468]; regulation of oxidative phosphorylation [GO:0002082]; removal of superoxide radicals [GO:0019430]; response to iron(III) ion [GO:0010041]; response to manganese ion [GO:0010042]; response to zinc ion [GO:0010043]; serotonin metabolic process [GO:0042428]; skin development [GO:0043588]; T-helper cell differentiation [GO:0042093]; tryptophan metabolic process [GO:0006568] GO:0001568; GO:0001701; GO:0001889; GO:0001974; GO:0002082; GO:0005375; GO:0005507; GO:0005524; GO:0005634; GO:0005770; GO:0005783; GO:0005794; GO:0005802; GO:0005829; GO:0005886; GO:0005902; GO:0006568; GO:0006584; GO:0006825; GO:0006878; GO:0007005; GO:0007565; GO:0007595; GO:0007626; GO:0010041; GO:0010042; GO:0010043; GO:0010273; GO:0010468; GO:0010592; GO:0014069; GO:0015677; GO:0016020; GO:0016323; GO:0016324; GO:0016532; GO:0016887; GO:0018205; GO:0019430; GO:0021702; GO:0021860; GO:0021954; GO:0030140; GO:0030141; GO:0030198; GO:0030199; GO:0030424; GO:0030425; GO:0030670; GO:0031069; GO:0031252; GO:0031267; GO:0031526; GO:0031901; GO:0032588; GO:0032767; GO:0032773; GO:0033162; GO:0034760; GO:0036120; GO:0042093; GO:0042414; GO:0042415; GO:0042417; GO:0042428; GO:0043005; GO:0043025; GO:0043085; GO:0043204; GO:0043473; GO:0043588; GO:0043682; GO:0045121; GO:0045793; GO:0048023; GO:0048251; GO:0048286; GO:0048471; GO:0048812; GO:0050679; GO:0051087; GO:0051216; GO:0051542; GO:0055070; GO:0060003; GO:0071230; GO:0071236; GO:0071276; GO:0071279; GO:0071280; GO:0071281; GO:0071284; GO:0071456; GO:0140581; GO:1903036; GO:1903136; GO:1904754; GO:1904959 25542 XM_044320461.1 919 430 684 920 668 Q04656 4.48e-44 Copper-transporting ATPase 1 (EC 7.2.2.8) (Copper pump 1) (Menkes disease-associated protein) Homo sapiens (Human) blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cartilage development [GO:0051216]; catecholamine metabolic process [GO:0006584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amino acid stimulus [GO:0071230]; cellular response to antibiotic [GO:0071236]; cellular response to cadmium ion [GO:0071276]; cellular response to cobalt ion [GO:0071279]; cellular response to copper ion [GO:0071280]; cellular response to hypoxia [GO:0071456]; cellular response to iron ion [GO:0071281]; cellular response to lead ion [GO:0071284]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; central nervous system neuron development [GO:0021954]; cerebellar Purkinje cell differentiation [GO:0021702]; collagen fibril organization [GO:0030199]; copper ion export [GO:0060003]; copper ion homeostasis [GO:0055070]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; detoxification of copper ion [GO:0010273]; dopamine metabolic process [GO:0042417]; elastic fiber assembly [GO:0048251]; elastin biosynthetic process [GO:0051542]; epinephrine metabolic process [GO:0042414]; extracellular matrix organization [GO:0030198]; female pregnancy [GO:0007565]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; lactation [GO:0007595]; liver development [GO:0001889]; locomotory behavior [GO:0007626]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; negative regulation of iron ion transmembrane transport [GO:0034760]; neuron projection morphogenesis [GO:0048812]; norepinephrine metabolic process [GO:0042415]; peptidyl-lysine modification [GO:0018205]; pigmentation [GO:0043473]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell size [GO:0045793]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of response to wounding [GO:1903036]; positive regulation of tyrosinase activity [GO:0032773]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; pyramidal neuron development [GO:0021860]; regulation of cytochrome-c oxidase activity [GO:1904959]; regulation of gene expression [GO:0010468]; regulation of oxidative phosphorylation [GO:0002082]; removal of superoxide radicals [GO:0019430]; response to iron(III) ion [GO:0010041]; response to manganese ion [GO:0010042]; response to zinc ion [GO:0010043]; serotonin metabolic process [GO:0042428]; skin development [GO:0043588]; T-helper cell differentiation [GO:0042093]; tryptophan metabolic process [GO:0006568] GO:0001568; GO:0001701; GO:0001889; GO:0001974; GO:0002082; GO:0005375; GO:0005507; GO:0005524; GO:0005634; GO:0005770; GO:0005783; GO:0005794; GO:0005802; GO:0005829; GO:0005886; GO:0005902; GO:0006568; GO:0006584; GO:0006825; GO:0006878; GO:0007005; GO:0007565; GO:0007595; GO:0007626; GO:0010041; GO:0010042; GO:0010043; GO:0010273; GO:0010468; GO:0010592; GO:0014069; GO:0015677; GO:0016020; GO:0016323; GO:0016324; GO:0016532; GO:0016887; GO:0018205; GO:0019430; GO:0021702; GO:0021860; GO:0021954; GO:0030140; GO:0030141; GO:0030198; GO:0030199; GO:0030424; GO:0030425; GO:0030670; GO:0031069; GO:0031252; GO:0031267; GO:0031526; GO:0031901; GO:0032588; GO:0032767; GO:0032773; GO:0033162; GO:0034760; GO:0036120; GO:0042093; GO:0042414; GO:0042415; GO:0042417; GO:0042428; GO:0043005; GO:0043025; GO:0043085; GO:0043204; GO:0043473; GO:0043588; GO:0043682; GO:0045121; GO:0045793; GO:0048023; GO:0048251; GO:0048286; GO:0048471; GO:0048812; GO:0050679; GO:0051087; GO:0051216; GO:0051542; GO:0055070; GO:0060003; GO:0071230; GO:0071236; GO:0071276; GO:0071279; GO:0071280; GO:0071281; GO:0071284; GO:0071456; GO:0140581; GO:1903036; GO:1903136; GO:1904754; GO:1904959 25543 XM_044320461.1 919 430 684 920 668 Q04656 1.28e-42 Copper-transporting ATPase 1 (EC 7.2.2.8) (Copper pump 1) (Menkes disease-associated protein) Homo sapiens (Human) blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cartilage development [GO:0051216]; catecholamine metabolic process [GO:0006584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amino acid stimulus [GO:0071230]; cellular response to antibiotic [GO:0071236]; cellular response to cadmium ion [GO:0071276]; cellular response to cobalt ion [GO:0071279]; cellular response to copper ion [GO:0071280]; cellular response to hypoxia [GO:0071456]; cellular response to iron ion [GO:0071281]; cellular response to lead ion [GO:0071284]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; central nervous system neuron development [GO:0021954]; cerebellar Purkinje cell differentiation [GO:0021702]; collagen fibril organization [GO:0030199]; copper ion export [GO:0060003]; copper ion homeostasis [GO:0055070]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; detoxification of copper ion [GO:0010273]; dopamine metabolic process [GO:0042417]; elastic fiber assembly [GO:0048251]; elastin biosynthetic process [GO:0051542]; epinephrine metabolic process [GO:0042414]; extracellular matrix organization [GO:0030198]; female pregnancy [GO:0007565]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; lactation [GO:0007595]; liver development [GO:0001889]; locomotory behavior [GO:0007626]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; negative regulation of iron ion transmembrane transport [GO:0034760]; neuron projection morphogenesis [GO:0048812]; norepinephrine metabolic process [GO:0042415]; peptidyl-lysine modification [GO:0018205]; pigmentation [GO:0043473]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell size [GO:0045793]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of response to wounding [GO:1903036]; positive regulation of tyrosinase activity [GO:0032773]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; pyramidal neuron development [GO:0021860]; regulation of cytochrome-c oxidase activity [GO:1904959]; regulation of gene expression [GO:0010468]; regulation of oxidative phosphorylation [GO:0002082]; removal of superoxide radicals [GO:0019430]; response to iron(III) ion [GO:0010041]; response to manganese ion [GO:0010042]; response to zinc ion [GO:0010043]; serotonin metabolic process [GO:0042428]; skin development [GO:0043588]; T-helper cell differentiation [GO:0042093]; tryptophan metabolic process [GO:0006568] GO:0001568; GO:0001701; GO:0001889; GO:0001974; GO:0002082; GO:0005375; GO:0005507; GO:0005524; GO:0005634; GO:0005770; GO:0005783; GO:0005794; GO:0005802; GO:0005829; GO:0005886; GO:0005902; GO:0006568; GO:0006584; GO:0006825; GO:0006878; GO:0007005; GO:0007565; GO:0007595; GO:0007626; GO:0010041; GO:0010042; GO:0010043; GO:0010273; GO:0010468; GO:0010592; GO:0014069; GO:0015677; GO:0016020; GO:0016323; GO:0016324; GO:0016532; GO:0016887; GO:0018205; GO:0019430; GO:0021702; GO:0021860; GO:0021954; GO:0030140; GO:0030141; GO:0030198; GO:0030199; GO:0030424; GO:0030425; GO:0030670; GO:0031069; GO:0031252; GO:0031267; GO:0031526; GO:0031901; GO:0032588; GO:0032767; GO:0032773; GO:0033162; GO:0034760; GO:0036120; GO:0042093; GO:0042414; GO:0042415; GO:0042417; GO:0042428; GO:0043005; GO:0043025; GO:0043085; GO:0043204; GO:0043473; GO:0043588; GO:0043682; GO:0045121; GO:0045793; GO:0048023; GO:0048251; GO:0048286; GO:0048471; GO:0048812; GO:0050679; GO:0051087; GO:0051216; GO:0051542; GO:0055070; GO:0060003; GO:0071230; GO:0071236; GO:0071276; GO:0071279; GO:0071280; GO:0071281; GO:0071284; GO:0071456; GO:0140581; GO:1903036; GO:1903136; GO:1904754; GO:1904959 25544 XM_044320461.1 919 430 684 920 668 Q04656 3.26e-32 Copper-transporting ATPase 1 (EC 7.2.2.8) (Copper pump 1) (Menkes disease-associated protein) Homo sapiens (Human) blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cartilage development [GO:0051216]; catecholamine metabolic process [GO:0006584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amino acid stimulus [GO:0071230]; cellular response to antibiotic [GO:0071236]; cellular response to cadmium ion [GO:0071276]; cellular response to cobalt ion [GO:0071279]; cellular response to copper ion [GO:0071280]; cellular response to hypoxia [GO:0071456]; cellular response to iron ion [GO:0071281]; cellular response to lead ion [GO:0071284]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; central nervous system neuron development [GO:0021954]; cerebellar Purkinje cell differentiation [GO:0021702]; collagen fibril organization [GO:0030199]; copper ion export [GO:0060003]; copper ion homeostasis [GO:0055070]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; detoxification of copper ion [GO:0010273]; dopamine metabolic process [GO:0042417]; elastic fiber assembly [GO:0048251]; elastin biosynthetic process [GO:0051542]; epinephrine metabolic process [GO:0042414]; extracellular matrix organization [GO:0030198]; female pregnancy [GO:0007565]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; lactation [GO:0007595]; liver development [GO:0001889]; locomotory behavior [GO:0007626]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; negative regulation of iron ion transmembrane transport [GO:0034760]; neuron projection morphogenesis [GO:0048812]; norepinephrine metabolic process [GO:0042415]; peptidyl-lysine modification [GO:0018205]; pigmentation [GO:0043473]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell size [GO:0045793]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of response to wounding [GO:1903036]; positive regulation of tyrosinase activity [GO:0032773]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; pyramidal neuron development [GO:0021860]; regulation of cytochrome-c oxidase activity [GO:1904959]; regulation of gene expression [GO:0010468]; regulation of oxidative phosphorylation [GO:0002082]; removal of superoxide radicals [GO:0019430]; response to iron(III) ion [GO:0010041]; response to manganese ion [GO:0010042]; response to zinc ion [GO:0010043]; serotonin metabolic process [GO:0042428]; skin development [GO:0043588]; T-helper cell differentiation [GO:0042093]; tryptophan metabolic process [GO:0006568] GO:0001568; GO:0001701; GO:0001889; GO:0001974; GO:0002082; GO:0005375; GO:0005507; GO:0005524; GO:0005634; GO:0005770; GO:0005783; GO:0005794; GO:0005802; GO:0005829; GO:0005886; GO:0005902; GO:0006568; GO:0006584; GO:0006825; GO:0006878; GO:0007005; GO:0007565; GO:0007595; GO:0007626; GO:0010041; GO:0010042; GO:0010043; GO:0010273; GO:0010468; GO:0010592; GO:0014069; GO:0015677; GO:0016020; GO:0016323; GO:0016324; GO:0016532; GO:0016887; GO:0018205; GO:0019430; GO:0021702; GO:0021860; GO:0021954; GO:0030140; GO:0030141; GO:0030198; GO:0030199; GO:0030424; GO:0030425; GO:0030670; GO:0031069; GO:0031252; GO:0031267; GO:0031526; GO:0031901; GO:0032588; GO:0032767; GO:0032773; GO:0033162; GO:0034760; GO:0036120; GO:0042093; GO:0042414; GO:0042415; GO:0042417; GO:0042428; GO:0043005; GO:0043025; GO:0043085; GO:0043204; GO:0043473; GO:0043588; GO:0043682; GO:0045121; GO:0045793; GO:0048023; GO:0048251; GO:0048286; GO:0048471; GO:0048812; GO:0050679; GO:0051087; GO:0051216; GO:0051542; GO:0055070; GO:0060003; GO:0071230; GO:0071236; GO:0071276; GO:0071279; GO:0071280; GO:0071281; GO:0071284; GO:0071456; GO:0140581; GO:1903036; GO:1903136; GO:1904754; GO:1904959 25545 XM_044325805.1 176 382 362 176 294 Q28HF8 3.97e-126 Sodium/bile acid cotransporter 7 (Na(+)/bile acid cotransporter 7) (Solute carrier family 10 member 7) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) sodium ion transport [GO:0006814] GO:0000139; GO:0005789; GO:0005886; GO:0006814; GO:0015293 25546 XM_044309382.1 8 13 0 2 0 NA NA NA NA NA NA 25547 XM_029326919.2 6567 6615 3711 9686 6285 Q9DGG6 0 Adenylate cyclase type 9 (EC 4.6.1.1) (ATP pyrophosphate-lyase 9) (Adenylate cyclase type IX) (Adenylyl cyclase 9) Gallus gallus (Chicken) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cAMP biosynthetic process [GO:0006171]; intracellular signal transduction [GO:0035556] GO:0004016; GO:0005524; GO:0005886; GO:0006171; GO:0007189; GO:0016020; GO:0035556; GO:0046872; GO:0071880 25548 XM_044324446.1 1098 4 3 4 19 NA NA NA NA NA NA 25549 XM_044318498.1 0 31 16 0 0 NA NA NA NA NA NA 25550 XM_029331512.2 260 718 180 507 193 NA NA NA NA NA NA 25551 XM_044312483.1 3 2 2 1 7 NA NA NA NA NA NA 25552 XM_029336438.2 143 94 221 117 353 Q8NCG7 3.4e-111 Diacylglycerol lipase-beta (DAGL-beta) (DGL-beta) (EC 3.1.1.116) (KCCR13L) (PUFA-specific triacylglycerol lipase) (EC 3.1.1.3) (Sn1-specific diacylglycerol lipase beta) Homo sapiens (Human) arachidonic acid metabolic process [GO:0019369]; endocannabinoid signaling pathway [GO:0071926]; lipid catabolic process [GO:0016042]; neuroblast proliferation [GO:0007405]; neurogenesis [GO:0022008]; neurotransmitter biosynthetic process [GO:0042136]; positive regulation of triglyceride catabolic process [GO:0010898]; prostaglandin biosynthetic process [GO:0001516]; regulation of inflammatory response [GO:0050727] GO:0001516; GO:0004806; GO:0005654; GO:0005737; GO:0005765; GO:0005886; GO:0007405; GO:0010898; GO:0016042; GO:0016298; GO:0019369; GO:0022008; GO:0042136; GO:0046872; GO:0047372; GO:0050727; GO:0071926 25553 XR_006396084.1 127 69 25 112 51 O35276 5.36e-30 Neuropilin-2 (Vascular endothelial cell growth factor 165 receptor 2) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; cellular response to leukemia inhibitory factor [GO:1990830]; dorsal root ganglion morphogenesis [GO:1904835]; facial nerve structural organization [GO:0021612]; facioacoustic ganglion development [GO:1903375]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; heart development [GO:0007507]; negative chemotaxis [GO:0050919]; nerve development [GO:0021675]; neural crest cell migration [GO:0001755]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; neuron migration [GO:0001764]; outflow tract septum morphogenesis [GO:0003148]; regulation of postsynapse organization [GO:0099175]; semaphorin-plexin signaling pathway involved in neuron projection guidance [GO:1902285]; sensory neuron axon guidance [GO:0097374]; sympathetic ganglion development [GO:0061549]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491]; trigeminal ganglion development [GO:0061551]; trunk neural crest cell migration [GO:0036484]; ventral trunk neural crest cell migration [GO:0036486]; vestibulocochlear nerve structural organization [GO:0021649] GO:0001525; GO:0001755; GO:0001764; GO:0003148; GO:0005021; GO:0005886; GO:0007411; GO:0007507; GO:0008201; GO:0017154; GO:0021612; GO:0021649; GO:0021675; GO:0021828; GO:0030424; GO:0036484; GO:0036486; GO:0038023; GO:0045211; GO:0046872; GO:0048846; GO:0050919; GO:0061549; GO:0061551; GO:0097374; GO:0097490; GO:0097491; GO:0098978; GO:0099175; GO:1901166; GO:1902285; GO:1903375; GO:1904835; GO:1990830 25554 XM_044316780.1 1197 965 679 1021 1029 Q5ZLT0 0 Exportin-7 Gallus gallus (Chicken) protein export from nucleus [GO:0006611] GO:0005049; GO:0005643; GO:0005737; GO:0006611; GO:0031267 25555 XM_029351247.2 18 15 26 28 49 A8Y5U1 3.25e-40 RAB7A-interacting MON1-CCZ1 complex subunit 1 (UPF0600 protein C5orf51 homolog) Danio rerio (Zebrafish) (Brachydanio rerio) mitophagy [GO:0000423] GO:0000423; GO:0005829 25556 XM_029326032.2 71 30 46 21 141 NA NA NA NA NA NA 25557 XM_044315646.1 93 93 78 132 99 Q9W6S5 3.15e-143 Allantoicase (EC 3.5.3.4) (Allantoate amidinohydrolase) Xenopus laevis (African clawed frog) allantoin catabolic process [GO:0000256]; purine nucleobase metabolic process [GO:0006144] GO:0000256; GO:0004037; GO:0006144 25558 XM_029333228.2 0 0 0 10 1 O75899 3.37e-74 Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51) (HG20) Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway [GO:0007186]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; neuron-glial cell signaling [GO:0150099]; synaptic transmission, GABAergic [GO:0051932] GO:0004888; GO:0004965; GO:0005737; GO:0005886; GO:0007186; GO:0007193; GO:0007194; GO:0007214; GO:0007268; GO:0038039; GO:0043005; GO:0045211; GO:0046982; GO:0051932; GO:0150099; GO:1902710; GO:1902712 25559 XM_029325836.2 0 50 75 89 0 NA NA NA NA NA NA 25560 XM_044307871.1 83 14 54 41 133 NA NA NA NA NA NA 25561 XM_044321241.1 0 0 17 0 0 NA NA NA NA NA NA 25562 XM_044328134.1 281 487 44 333 741 Q5RCY5 1.91e-60 Protein asteroid homolog 1 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0004518 25563 XR_006397471.1 14 5 13 0 6 NA NA NA NA NA NA 25564 XM_029342019.2 876 945 573 988 1244 O00567 0 Nucleolar protein 56 (Nucleolar protein 5A) Homo sapiens (Human) rRNA processing [GO:0006364] GO:0001650; GO:0003723; GO:0005654; GO:0005730; GO:0005732; GO:0005737; GO:0006364; GO:0016020; GO:0030515; GO:0031428; GO:0032040; GO:0045296; GO:0070761; GO:1990226 25565 XM_029354391.2 13 6 25 6 9 NA NA NA NA NA NA 25566 XM_044312982.1 0 9 3 124 88 NA NA NA NA NA NA 25567 XM_029337953.2 288 266 229 336 186 Q96AX1 0 Vacuolar protein sorting-associated protein 33A (hVPS33A) Homo sapiens (Human) autophagosome maturation [GO:0097352]; endosomal vesicle fusion [GO:0034058]; endosome to lysosome transport [GO:0008333]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; melanosome localization [GO:0032400]; platelet formation [GO:0030220]; regulation of developmental pigmentation [GO:0048070]; regulation of lysosomal lumen pH [GO:0035751]; regulation of SNARE complex assembly [GO:0035542]; vesicle-mediated transport [GO:0016192] GO:0005764; GO:0005765; GO:0005769; GO:0005770; GO:0005773; GO:0005776; GO:0006886; GO:0008333; GO:0010008; GO:0016192; GO:0030136; GO:0030220; GO:0030897; GO:0031902; GO:0032400; GO:0032418; GO:0033263; GO:0034058; GO:0035542; GO:0035751; GO:0048070; GO:0048471; GO:0097352 25568 XR_003826870.2 88 245 95 182 62 NA NA NA NA NA NA 25569 XM_044319272.1 303 214 82 130 186 NA NA NA NA NA NA 25570 XM_029347911.2 0 0 0 0 10 NA NA NA NA NA NA 25571 XM_029351652.2 37 0 0 0 23 NA NA NA NA NA NA 25572 XM_044316184.1 8 0 0 0 0 NA NA NA NA NA NA 25573 XM_044326223.1 8 16 7 1 5 NA NA NA NA NA NA 25574 XM_044326439.1 2 0 7 0 28 NA NA NA NA NA NA 25575 XM_029341517.2 0 7 387 0 0 Q02974 2.14e-98 Ketohexokinase (EC 2.7.1.3) (Hepatic fructokinase) Rattus norvegicus (Rat) carbohydrate catabolic process [GO:0016052]; carbohydrate phosphorylation [GO:0046835]; fructose catabolic process [GO:0006001]; fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; fructose metabolic process [GO:0006000]; regulation of glycogen metabolic process [GO:0070873]; response to fructose [GO:0009750]; response to glucose [GO:0009749]; response to insulin [GO:0032868]; response to sucrose [GO:0009744]; response to zinc ion [GO:0010043] GO:0004454; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006000; GO:0006001; GO:0009744; GO:0009749; GO:0009750; GO:0010043; GO:0016052; GO:0032868; GO:0046835; GO:0061624; GO:0070873 25576 XM_044317696.1 4184 3225 1554 2624 1893 NA NA NA NA NA NA 25577 XM_044325553.1 6613 3976 2701 5982 8502 Q7ZVF3 0 Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (EC 1.3.5.1) (Flavoprotein subunit of complex II) (Fp) Danio rerio (Zebrafish) (Brachydanio rerio) mitochondrial electron transport, succinate to ubiquinone [GO:0006121]; tricarboxylic acid cycle [GO:0006099] GO:0000104; GO:0005749; GO:0006099; GO:0006121; GO:0008177; GO:0009055; GO:0050660; GO:0102040 25578 XR_006391424.1 8 8 12 0 0 NA NA NA NA NA NA 25579 XR_006395713.1 61 29 26 64 108 NA NA NA NA NA NA 25580 XM_029347036.2 1525 1657 695 1585 867 NA NA NA NA NA NA 25581 XR_006398024.1 1570 739 615 1063 986 NA NA NA NA NA NA 25582 XM_029350155.2 293 341 449 762 512 NA NA NA NA NA NA 25583 XR_006395009.1 1 0 0 6 0 NA NA NA NA NA NA 25584 XM_044324265.1 0 286 0 257 0 Q4LDE5 3.16e-133 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 25585 XM_044324265.1 0 286 0 257 0 Q4LDE5 2.44e-122 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 25586 XM_044324265.1 0 286 0 257 0 Q4LDE5 4.1e-121 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 25587 XM_044324265.1 0 286 0 257 0 Q4LDE5 5.63e-102 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 25588 XM_044324265.1 0 286 0 257 0 Q4LDE5 2.8e-99 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 25589 XR_006397501.1 140 0 0 0 0 NA NA NA NA NA NA 25590 XM_044327224.1 527 854 1014 1424 1220 O75581 0 Low-density lipoprotein receptor-related protein 6 (LRP-6) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; chemical synaptic transmission [GO:0007268]; dopaminergic neuron differentiation [GO:0071542]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001933; GO:0005041; GO:0005102; GO:0005109; GO:0005576; GO:0005783; GO:0005886; GO:0006469; GO:0007204; GO:0007268; GO:0009986; GO:0014029; GO:0014033; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0031410; GO:0031901; GO:0034392; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043434; GO:0044335; GO:0044340; GO:0045121; GO:0045202; GO:0045787; GO:0045893; GO:0045944; GO:0051091; GO:0060070; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072659; GO:0090118; GO:0090244; GO:0098609; GO:1904928; GO:1904948; GO:1904953; GO:1990851; GO:1990909 25591 XM_044327224.1 527 854 1014 1424 1220 O75581 4.62e-172 Low-density lipoprotein receptor-related protein 6 (LRP-6) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; chemical synaptic transmission [GO:0007268]; dopaminergic neuron differentiation [GO:0071542]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001933; GO:0005041; GO:0005102; GO:0005109; GO:0005576; GO:0005783; GO:0005886; GO:0006469; GO:0007204; GO:0007268; GO:0009986; GO:0014029; GO:0014033; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0031410; GO:0031901; GO:0034392; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043434; GO:0044335; GO:0044340; GO:0045121; GO:0045202; GO:0045787; GO:0045893; GO:0045944; GO:0051091; GO:0060070; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072659; GO:0090118; GO:0090244; GO:0098609; GO:1904928; GO:1904948; GO:1904953; GO:1990851; GO:1990909 25592 XM_044327224.1 527 854 1014 1424 1220 O75581 8.21e-89 Low-density lipoprotein receptor-related protein 6 (LRP-6) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; chemical synaptic transmission [GO:0007268]; dopaminergic neuron differentiation [GO:0071542]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001933; GO:0005041; GO:0005102; GO:0005109; GO:0005576; GO:0005783; GO:0005886; GO:0006469; GO:0007204; GO:0007268; GO:0009986; GO:0014029; GO:0014033; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0031410; GO:0031901; GO:0034392; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043434; GO:0044335; GO:0044340; GO:0045121; GO:0045202; GO:0045787; GO:0045893; GO:0045944; GO:0051091; GO:0060070; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072659; GO:0090118; GO:0090244; GO:0098609; GO:1904928; GO:1904948; GO:1904953; GO:1990851; GO:1990909 25593 XM_044326944.1 1591 1050 984 1663 1436 Q9I8E6 0 Coatomer subunit gamma-2 (Gamma-2-coat protein) (Gamma-2-COP) Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0005198; GO:0006886; GO:0016192; GO:0030126 25594 XM_029334651.2 50 6 38 8 17 B8V7Q1 0 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 25595 XM_029334651.2 50 6 38 8 17 B8V7Q1 1.14e-127 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 25596 XM_029334651.2 50 6 38 8 17 B8V7Q1 5.58e-85 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 25597 XM_029334651.2 50 6 38 8 17 B8V7Q1 5.04e-78 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 25598 XM_029334651.2 50 6 38 8 17 B8V7Q1 3.74e-76 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 25599 XM_029334651.2 50 6 38 8 17 B8V7Q1 1.86e-31 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 25600 XM_029334651.2 50 6 38 8 17 B8V7Q1 1.05e-25 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 25601 XM_029327262.2 45 0 0 0 34 A4QNP7 2.5e-29 Doublesex- and mab-3-related transcription factor A2 (Doublesex- and mab-3-related transcription factor 5) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006355; GO:0043565; GO:0046872 25602 XM_029326126.2 33 70 19 28 49 Q8BHB0 3.13e-24 Nucleotide-binding oligomerization domain-containing protein 1 (Caspase recruitment domain-containing protein 4) Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cellular response to muramyl dipeptide [GO:0071225]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; ERK1 and ERK2 cascade [GO:0070371]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of cell death [GO:0010942]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of xenophagy [GO:1904417]; regulation of apoptotic process [GO:0042981]; stress-activated MAPK cascade [GO:0051403]; xenophagy [GO:0098792] GO:0002221; GO:0002606; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006915; GO:0006919; GO:0007249; GO:0007254; GO:0010942; GO:0016045; GO:0016323; GO:0016324; GO:0032731; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0035556; GO:0038187; GO:0042742; GO:0042802; GO:0042803; GO:0042981; GO:0043123; GO:0043280; GO:0044877; GO:0045087; GO:0045335; GO:0046330; GO:0050700; GO:0050830; GO:0051000; GO:0051092; GO:0051403; GO:0060907; GO:0070371; GO:0070374; GO:0071225; GO:0098792; GO:1901224; GO:1904417 25603 XR_006394210.1 5 0 0 175 108 NA NA NA NA NA NA 25604 XM_029343189.2 256 252 101 197 180 NA NA NA NA NA NA 25605 XM_029339903.2 369 284 248 262 344 NA NA NA NA NA NA 25606 XM_029333763.2 498 424 210 402 163 Q9Z1N4 7.78e-108 3'(2'),5'-bisphosphate nucleotidase 1 (EC 3.1.3.7) (Bisphosphate 3'-nucleotidase 1) (PAP-inositol 1,4-phosphatase) (PIP) (scHAL2 analogous 3) Rattus norvegicus (Rat) inositol phosphate dephosphorylation [GO:0046855]; phosphatidylinositol phosphate biosynthetic process [GO:0046854] GO:0000287; GO:0004441; GO:0008441; GO:0046854; GO:0046855 25607 XM_029333532.2 15539 12640 8106 12860 7345 Q8R3Y8 1.47e-48 Interferon regulatory factor 2-binding protein 1 (IRF-2-binding protein 1) (IRF-2BP1) (Probable E3 ubiquitin-protein ligase IRF2BP1) (EC 2.3.2.27) (Probable RING-type E3 ubiquitin transferase IRF2BP1) Mus musculus (Mouse) negative regulation of transcription by RNA polymerase II [GO:0000122]; protein polyubiquitination [GO:0000209]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000209; GO:0003714; GO:0005634; GO:0005654; GO:0006357; GO:0046872; GO:0061630 25608 XM_029333532.2 15539 12640 8106 12860 7345 Q8R3Y8 2.34e-30 Interferon regulatory factor 2-binding protein 1 (IRF-2-binding protein 1) (IRF-2BP1) (Probable E3 ubiquitin-protein ligase IRF2BP1) (EC 2.3.2.27) (Probable RING-type E3 ubiquitin transferase IRF2BP1) Mus musculus (Mouse) negative regulation of transcription by RNA polymerase II [GO:0000122]; protein polyubiquitination [GO:0000209]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000209; GO:0003714; GO:0005634; GO:0005654; GO:0006357; GO:0046872; GO:0061630 25609 XM_044326062.1 10 41 11 95 14 NA NA NA NA NA NA 25610 XM_044324592.1 1 1 0 11 0 NA NA NA NA NA NA 25611 XR_006394178.1 0 0 0 1 73 NA NA NA NA NA NA 25612 XR_006394185.1 128 13 33 16 354 NA NA NA NA NA NA 25613 XM_044326338.1 91 115 79 33 130 NA NA NA NA NA NA 25614 XM_029331756.2 361 324 259 656 484 Q49GP3 0 Phosphatidylinositol 4-kinase beta (PI4K-beta) (PI4Kbeta) (PtdIns 4-kinase beta) (EC 2.7.1.67) Danio rerio (Zebrafish) (Brachydanio rerio) phosphatidylinositol phosphate biosynthetic process [GO:0046854]; phosphatidylinositol-mediated signaling [GO:0048015]; phosphorylation [GO:0016310]; semicircular canal development [GO:0060872] GO:0004430; GO:0005524; GO:0005737; GO:0005741; GO:0016020; GO:0016310; GO:0030867; GO:0046854; GO:0048015; GO:0052742; GO:0060872 25615 XM_044327789.1 0 0 0 0 19 NA NA NA NA NA NA 25616 XM_044307306.1 0 0 0 403 0 E9PSU6 0 Pecanex-like protein 1 (Pecanex 1) (Pecanex homolog protein 1) Rattus norvegicus (Rat) NA GO:0016020 25617 XM_044307306.1 0 0 0 403 0 E9PSU6 1.12e-28 Pecanex-like protein 1 (Pecanex 1) (Pecanex homolog protein 1) Rattus norvegicus (Rat) NA GO:0016020 25618 XM_044307306.1 0 0 0 403 0 E9PSU6 8.48e-21 Pecanex-like protein 1 (Pecanex 1) (Pecanex homolog protein 1) Rattus norvegicus (Rat) NA GO:0016020 25619 XM_044319489.1 43 32 30 77 69 NA NA NA NA NA NA 25620 XM_044328228.1 51 122 87 26 104 Q9BX70 3.43e-71 BTB/POZ domain-containing protein 2 Homo sapiens (Human) neurogenesis [GO:0022008] GO:0000932; GO:0005829; GO:0022008 25621 XM_029346299.2 163 45 19 192 143 B7W114 0 Cephalotoxin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 25622 XM_029343620.2 13 29 48 27 33 NA NA NA NA NA NA 25623 XM_044308041.1 0 0 16 0 76 B3EWZ3 2.15e-93 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 25624 XM_044308041.1 0 0 16 0 76 B3EWZ3 9.82e-86 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 25625 XM_044308041.1 0 0 16 0 76 B3EWZ3 2.55e-74 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 25626 XM_044308041.1 0 0 16 0 76 B3EWZ3 2.17e-70 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 25627 XM_044308041.1 0 0 16 0 76 B3EWZ3 9.05e-69 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 25628 XM_044308041.1 0 0 16 0 76 B3EWZ3 2.04e-65 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 25629 XM_044308041.1 0 0 16 0 76 B3EWZ3 2.4e-64 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 25630 XM_044308041.1 0 0 16 0 76 B3EWZ3 6.25e-30 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 25631 XR_006396701.1 1 43 0 0 0 NA NA NA NA NA NA 25632 XM_029356316.2 924 576 373 614 1305 Q66H56 1.82e-59 TELO2-interacting protein 2 Rattus norvegicus (Rat) NA GO:0005654; GO:0005813; GO:0005829; GO:0070209; GO:0110078 25633 XM_044319914.1 77 30 17 49 41 NA NA NA NA NA NA 25634 XM_044328741.1 0 4 11 11 0 NA NA NA NA NA NA 25635 XM_029354873.2 33 41 31 47 25 NA NA NA NA NA NA 25636 XM_044328528.1 1 4 0 1 8 Q6L8S8 3.85e-51 Beta-1,4-N-acetylgalactosaminyltransferase 3 (Beta4GalNAc-T3) (Beta4GalNAcT3) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase III) (N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 2) (NGalNAc-T2) Mus musculus (Mouse) chondroitin sulfate biosynthetic process [GO:0030206] GO:0005794; GO:0008376; GO:0030206; GO:0032580; GO:0033842; GO:0043231; GO:0047238 25637 XM_044315235.1 88 4 25 9 31 Q7ZYL5 2e-136 Kinesin-like protein KIF22-B (Chromokinesin kid-B) (Xkid-B) Xenopus laevis (African clawed frog) microtubule-based movement [GO:0007018] GO:0003677; GO:0003777; GO:0005524; GO:0005634; GO:0005737; GO:0005874; GO:0007018; GO:0008017 25638 XM_044319310.1 625 0 499 0 571 P18130 9.23e-30 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) Bos taurus (Bovine) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of vasoconstriction [GO:0045907]; regulation of cardiac muscle contraction [GO:0055117] GO:0001996; GO:0004930; GO:0004937; GO:0005634; GO:0005737; GO:0005886; GO:0005901; GO:0007200; GO:0007204; GO:0007267; GO:0031965; GO:0043410; GO:0045907; GO:0046982; GO:0055117; GO:0071880 25639 XM_029346931.2 177 95 85 116 136 Q6EE22 0 RING finger protein unkempt homolog (Zinc finger CCCH domain-containing protein 5) Canis lupus familiaris (Dog) (Canis familiaris) cell morphogenesis involved in neuron differentiation [GO:0048667]; regulation of translation [GO:0006417] GO:0005737; GO:0006417; GO:0046872; GO:0048667; GO:1990715 25640 XM_029333530.2 0 18 299 382 537 P10079 1.17e-166 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 25641 XM_029333530.2 0 18 299 382 537 P10079 8.01e-159 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 25642 XM_029333530.2 0 18 299 382 537 P10079 4.05e-152 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 25643 XM_029333530.2 0 18 299 382 537 P10079 7.71e-125 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 25644 XM_029332672.2 1248 581 379 811 737 Q6NXT6 1.79e-165 Transmembrane anterior posterior transformation protein 1 homolog (Cytomegalovirus partial fusion receptor) Homo sapiens (Human) cartilage development [GO:0051216]; cell projection organization [GO:0030030]; embryonic skeletal system development [GO:0048706]; neural crest cell development [GO:0014032]; ossification [GO:0001503]; positive regulation of bone development [GO:1903012]; positive regulation of cartilage development [GO:0061036]; positive regulation of cilium assembly [GO:0045724] GO:0001503; GO:0005654; GO:0005789; GO:0005813; GO:0005829; GO:0014032; GO:0016020; GO:0016520; GO:0030030; GO:0036064; GO:0045724; GO:0048706; GO:0051216; GO:0061036; GO:1903012 25645 XM_044328582.1 0 85 0 0 0 Q7Z4T9 3.96e-55 Cilia- and flagella-associated protein 91 (CFAP91) (AMY-1-associating protein expressed in testis 1) (AAT-1) (MYCBP/AMY-1-associated testis-expressed protein 1) (Protein MAATS1) Homo sapiens (Human) axonemal central apparatus assembly [GO:1904158]; cell differentiation [GO:0030154]; cilium movement [GO:0003341]; spermatogenesis [GO:0007283] GO:0003341; GO:0005739; GO:0005930; GO:0007283; GO:0030154; GO:0031514; GO:1904158 25646 XM_044328582.1 0 85 0 0 0 Q7Z4T9 3.96e-55 Cilia- and flagella-associated protein 91 (CFAP91) (AMY-1-associating protein expressed in testis 1) (AAT-1) (MYCBP/AMY-1-associated testis-expressed protein 1) (Protein MAATS1) Homo sapiens (Human) axonemal central apparatus assembly [GO:1904158]; cell differentiation [GO:0030154]; cilium movement [GO:0003341]; spermatogenesis [GO:0007283] GO:0003341; GO:0005739; GO:0005930; GO:0007283; GO:0030154; GO:0031514; GO:1904158 25647 XM_044328582.1 0 85 0 0 0 Q7Z4T9 3.96e-55 Cilia- and flagella-associated protein 91 (CFAP91) (AMY-1-associating protein expressed in testis 1) (AAT-1) (MYCBP/AMY-1-associated testis-expressed protein 1) (Protein MAATS1) Homo sapiens (Human) axonemal central apparatus assembly [GO:1904158]; cell differentiation [GO:0030154]; cilium movement [GO:0003341]; spermatogenesis [GO:0007283] GO:0003341; GO:0005739; GO:0005930; GO:0007283; GO:0030154; GO:0031514; GO:1904158 25648 XM_029342045.2 146 82 65 448 622 Q28772 2.16e-31 Transcription factor 12 (TCF-12) (DNA-binding protein HTF4) (E-box-binding protein) (Transcription factor HTF-4) Papio hamadryas (Hamadryas baboon) cell differentiation [GO:0030154]; nervous system development [GO:0007399]; positive regulation of neuron differentiation [GO:0045666]; response to gonadotropin-releasing hormone [GO:0097210] GO:0005634; GO:0007399; GO:0030154; GO:0045666; GO:0046982; GO:0070888; GO:0097210 25649 XM_044318669.1 976 525 905 801 3759 NA NA NA NA NA NA 25650 XM_044320130.1 0 7 0 0 12 NA NA NA NA NA NA 25651 XM_029346879.2 69 17 20 77 81 NA NA NA NA NA NA 25652 XM_029329500.2 19 0 0 0 0 Q15102 4.54e-79 Platelet-activating factor acetylhydrolase IB subunit alpha1 (EC 3.1.1.47) (PAF acetylhydrolase 29 kDa subunit) (PAF-AH 29 kDa subunit) (PAF-AH subunit gamma) (PAFAH subunit gamma) Homo sapiens (Human) brain development [GO:0007420]; lipid catabolic process [GO:0016042]; lipid metabolic process [GO:0006629]; nervous system development [GO:0007399]; spermatogenesis [GO:0007283] GO:0003847; GO:0005737; GO:0005829; GO:0006629; GO:0007283; GO:0007399; GO:0007420; GO:0008247; GO:0016020; GO:0016042; GO:0042802; GO:0042803; GO:0044877; GO:0046982; GO:0047179 25653 XM_029325344.2 297 146 131 177 146 NA NA NA NA NA NA 25654 XM_044312544.1 130 0 100 2 0 Q96AY4 1.36e-108 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25655 XM_044312544.1 130 0 100 2 0 Q96AY4 3.87e-91 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25656 XM_044312544.1 130 0 100 2 0 Q96AY4 2.79e-87 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25657 XM_044312544.1 130 0 100 2 0 Q96AY4 5.76e-87 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25658 XM_044312544.1 130 0 100 2 0 Q96AY4 1.32e-84 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25659 XM_044312544.1 130 0 100 2 0 Q96AY4 1.35e-77 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25660 XM_044312544.1 130 0 100 2 0 Q96AY4 1.42e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25661 XM_044312544.1 130 0 100 2 0 Q96AY4 2.11e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25662 XM_044312544.1 130 0 100 2 0 Q96AY4 9.59e-68 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25663 XM_044326671.1 0 490 817 2365 4298 Q60HC7 0 Transketolase (TK) (EC 2.2.1.1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0004802; GO:0046872 25664 XM_044312210.1 48 0 0 19 6 NA NA NA NA NA NA 25665 XR_006392495.1 1 0 0 0 12 NA NA NA NA NA NA 25666 XM_029334811.2 0 7 0 0 0 NA NA NA NA NA NA 25667 XM_029340591.2 113 57 37 48 60 Q96QD5 1.1e-21 DEP domain-containing protein 7 (Protein TR2/D15) Homo sapiens (Human) intracellular signal transduction [GO:0035556] GO:0035556 25668 XM_044309215.1 0 4 0 13 68 NA NA NA NA NA NA 25669 XM_044315213.1 2278 1558 1638 3700 2310 NA NA NA NA NA NA 25670 XM_044324809.1 717 590 367 1081 310 Q8CHP8 5.94e-89 Glycerol-3-phosphate phosphatase (G3PP) (EC 3.1.3.21) (Aspartate-based ubiquitous Mg(2+)-dependent phosphatase) (AUM) (EC 3.1.3.48) (Phosphoglycolate phosphatase) (PGP) Mus musculus (Mouse) glycerol biosynthetic process [GO:0006114]; glycerophospholipid metabolic process [GO:0006650]; negative regulation of gluconeogenesis [GO:0045721] GO:0000121; GO:0000287; GO:0004725; GO:0005737; GO:0006114; GO:0006650; GO:0008967; GO:0016791; GO:0043136; GO:0043262; GO:0045721 25671 XR_006394446.1 122 34 0 72 14 NA NA NA NA NA NA 25672 XM_029346868.2 82 40 25 88 200 P48058 6.16e-94 Glutamate receptor 4 (GluR-4) (GluR4) (AMPA-selective glutamate receptor 4) (GluR-D) (Glutamate receptor ionotropic, AMPA 4) (GluA4) Homo sapiens (Human) glutamate receptor signaling pathway [GO:0007215]; negative regulation of smooth muscle cell apoptotic process [GO:0034392] GO:0001540; GO:0004970; GO:0004971; GO:0005886; GO:0007215; GO:0015276; GO:0030666; GO:0032281; GO:0034392; GO:0038023; GO:0043025; GO:0043197; GO:0045211; GO:0099507; GO:1903561 25673 XM_044318975.1 33 8 35 1 29 O73853 2.26e-98 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Ictalurus punctatus (Channel catfish) (Silurus punctatus) steroid biosynthetic process [GO:0006694] GO:0004508; GO:0005506; GO:0006694; GO:0016020; GO:0020037; GO:0047442 25674 XM_029346980.2 39 17 6 51 141 A1L1W9 7.23e-41 Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10) Danio rerio (Zebrafish) (Brachydanio rerio) aromatic amino acid transport [GO:0015801]; thyroid hormone transport [GO:0070327] GO:0005302; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0070327 25675 XM_044322784.1 7 18 43 26 8 NA NA NA NA NA NA 25676 XR_003826153.2 56 47 20 28 51 NA NA NA NA NA NA 25677 XR_006391894.1 65 0 38 0 0 NA NA NA NA NA NA 25678 XM_029327068.2 244 140 110 273 185 Q6ZN84 2.97e-71 Coiled-coil domain-containing protein 81 Homo sapiens (Human) NA GO:0005737; GO:0005813 25679 XM_029327068.2 244 140 110 273 185 Q6ZN84 8.25e-63 Coiled-coil domain-containing protein 81 Homo sapiens (Human) NA GO:0005737; GO:0005813 25680 XM_044316503.1 2 0 8 1 2 NA NA NA NA NA NA 25681 XM_044320352.1 2 8 4 15 0 NA NA NA NA NA NA 25682 XM_044308357.1 23 0 36 0 16 NA NA NA NA NA NA 25683 XM_029357049.2 1930 2398 994 1720 1231 Q5M9B7 1.28e-79 Oligosaccharyltransferase complex subunit ostc-B Xenopus laevis (African clawed frog) protein glycosylation [GO:0006486] GO:0006486; GO:0008250 25684 XM_029335405.2 703 425 365 590 446 Q92890 3.85e-111 Ubiquitin recognition factor in ER-associated degradation protein 1 (Ubiquitin fusion degradation protein 1) (UB fusion protein 1) Homo sapiens (Human) ER-associated misfolded protein catabolic process [GO:0071712]; negative regulation of RIG-I signaling pathway [GO:0039536]; negative regulation of type I interferon production [GO:0032480]; retrograde protein transport, ER to cytosol [GO:0030970]; skeletal system development [GO:0001501]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0001501; GO:0004843; GO:0005634; GO:0005654; GO:0005829; GO:0006511; GO:0030433; GO:0030970; GO:0031593; GO:0032480; GO:0034098; GO:0036435; GO:0036501; GO:0039536; GO:0071712 25685 XM_029351715.2 29 23 38 59 42 NA NA NA NA NA NA 25686 XM_029334972.2 3935 3617 2092 6572 2058 Q9Y6J8 5.36e-69 Serine/threonine/tyrosine-interacting-like protein 1 (Dual specificity phosphatase inhibitor MK-STYX) (Dual specificity protein phosphatase 24) (Inactive dual specificity protein phosphatase MK-STYX) (Map kinase phosphatase-like protein MK-STYX) Homo sapiens (Human) intracellular signal transduction [GO:0035556]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; negative regulation of stress granule assembly [GO:0062030]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of neuron projection development [GO:0010976]; protein dephosphorylation [GO:0006470]; regulation of intrinsic apoptotic signaling pathway [GO:2001242] GO:0001691; GO:0004864; GO:0005739; GO:0005759; GO:0006470; GO:0008138; GO:0010976; GO:0019903; GO:0032515; GO:0035556; GO:0062030; GO:2001242; GO:2001244 25687 XM_044314982.1 0 0 0 0 6 NA NA NA NA NA NA 25688 XR_006395830.1 5 1330 6 2 658 NA NA NA NA NA NA 25689 XM_044309503.1 31 0 9 1 68 NA NA NA NA NA NA 25690 XM_044309874.1 20 13 18 41 57 Q17RP2 1.69e-51 Tigger transposable element-derived protein 6 Homo sapiens (Human) NA GO:0003677; GO:0005634 25691 XM_044325242.1 541 231 40 360 361 Q61093 3.89e-177 Cytochrome b-245 heavy chain (EC 1.-.-.-) (CGD91-phox) (Cytochrome b(558) subunit beta) (Cytochrome b558 subunit beta) (Heme-binding membrane glycoprotein gp91phox) (Neutrophil cytochrome b 91 kDa polypeptide) (gp91-1) (gp91-phox) (p22 phagocyte B-cytochrome) Mus musculus (Mouse) cellular response to cadmium ion [GO:0071276]; cellular response to ethanol [GO:0071361]; cellular response to L-glutamine [GO:1904845]; defense response [GO:0006952]; hydrogen peroxide biosynthetic process [GO:0050665]; hypoxia-inducible factor-1alpha signaling pathway [GO:0097411]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; positive regulation of angiogenesis [GO:0045766]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of ion transmembrane transport [GO:0034765]; respiratory burst [GO:0045730]; response to aldosterone [GO:1904044]; response to angiotensin [GO:1990776]; response to nutrient [GO:0007584]; response to xenobiotic stimulus [GO:0009410]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801] GO:0005244; GO:0005635; GO:0005737; GO:0005739; GO:0005783; GO:0005791; GO:0005794; GO:0005886; GO:0006801; GO:0006952; GO:0006954; GO:0007584; GO:0009055; GO:0009410; GO:0016175; GO:0020037; GO:0030425; GO:0032760; GO:0034765; GO:0042554; GO:0043020; GO:0043025; GO:0045087; GO:0045335; GO:0045730; GO:0045766; GO:0046872; GO:0046982; GO:0050660; GO:0050665; GO:0071276; GO:0071361; GO:0097038; GO:0097411; GO:1904044; GO:1904845; GO:1990776 25692 XM_029326322.2 530 304 168 1184 592 Q9UBH6 0 Xenotropic and polytropic retrovirus receptor 1 (Protein SYG1 homolog) (Xenotropic and polytropic murine leukemia virus receptor X3) (X-receptor) Homo sapiens (Human) cellular phosphate ion homeostasis [GO:0030643]; cellular response to phosphate starvation [GO:0016036]; G protein-coupled receptor signaling pathway [GO:0007186]; phosphate ion transmembrane transport [GO:0035435]; phosphate ion transport [GO:0006817]; response to virus [GO:0009615] GO:0000822; GO:0001618; GO:0004888; GO:0004930; GO:0005737; GO:0005794; GO:0005886; GO:0006817; GO:0007186; GO:0009615; GO:0015114; GO:0015562; GO:0016036; GO:0030643; GO:0035435; GO:0038023 25693 XM_029331691.2 310 363 226 528 337 Q8C1B2 6.06e-42 Protein mono-ADP-ribosyltransferase TIPARP (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 14) (ARTD14) (TCDD-inducible poly [ADP-ribose] polymerase) Mus musculus (Mouse) androgen metabolic process [GO:0008209]; cellular response to organic cyclic compound [GO:0071407]; estrogen metabolic process [GO:0008210]; face morphogenesis [GO:0060325]; female gonad development [GO:0008585]; hemopoiesis [GO:0030097]; kidney development [GO:0001822]; negative regulation of gene expression [GO:0010629]; nitrogen compound metabolic process [GO:0006807]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of protein catabolic process [GO:0045732]; post-embryonic development [GO:0009791]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; smooth muscle tissue development [GO:0048745]; vasculogenesis [GO:0001570] GO:0000987; GO:0001570; GO:0001822; GO:0003950; GO:0005634; GO:0006807; GO:0008209; GO:0008210; GO:0008585; GO:0009791; GO:0010629; GO:0016779; GO:0030097; GO:0045732; GO:0046872; GO:0048008; GO:0048705; GO:0048745; GO:0060021; GO:0060325; GO:0071407; GO:0140803; GO:1990404 25694 XM_029329837.2 6214 6071 1926 3172 4767 Q9Y376 1.27e-153 Calcium-binding protein 39 (MO25alpha) (Protein Mo25) Homo sapiens (Human) activation of protein kinase activity [GO:0032147]; cellular hypotonic response [GO:0071476]; intracellular signal transduction [GO:0035556]; negative regulation of potassium ion transmembrane transport [GO:1901380]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; response to activity [GO:0014823]; response to thyroid hormone [GO:0097066]; signal transduction [GO:0007165] GO:0005576; GO:0005737; GO:0005829; GO:0007165; GO:0010800; GO:0014823; GO:0016020; GO:0018105; GO:0019900; GO:0030018; GO:0030295; GO:0032147; GO:0034774; GO:0035556; GO:0043539; GO:0070062; GO:0071476; GO:0071902; GO:0097066; GO:1901017; GO:1901380; GO:1902554; GO:1904813 25695 XM_029338376.2 0 0 15 0 0 A6QR44 3e-47 Microprocessor complex subunit DGCR8 (DiGeorge syndrome critical region 8 homolog) Bos taurus (Bovine) primary miRNA processing [GO:0031053] GO:0003725; GO:0005730; GO:0020037; GO:0031053; GO:0042802; GO:0046872; GO:0070877; GO:0070878 25696 XR_006398057.1 59 105 46 57 86 NA NA NA NA NA NA 25697 XM_029341506.2 3038 2167 1748 3416 3174 Q5RBE5 1.87e-170 GDP-L-fucose synthase (EC 1.1.1.271) (GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase) (Protein FX) (Red cell NADP(H)-binding protein) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) 'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904906] GO:0010595; GO:0016853; GO:0042351; GO:0050577; GO:1904906 25698 XM_029334424.2 15668 20876 10637 16692 11778 Q80TE4 0 Signal-induced proliferation-associated 1-like protein 2 (SIPA1-like protein 2) Mus musculus (Mouse) activation of GTPase activity [GO:0090630]; regulation of small GTPase mediated signal transduction [GO:0051056] GO:0005096; GO:0005737; GO:0051056; GO:0090630 25699 XM_029330801.2 1779 0 0 764 0 NA NA NA NA NA NA 25700 XM_029339044.2 27 4 24 13 112 NA NA NA NA NA NA 25701 XR_006392926.1 41 2 25 5 151 NA NA NA NA NA NA 25702 XM_029333367.2 0 36 0 0 0 P31335 0 Bifunctional purine biosynthesis protein ATIC (AICAR transformylase/inosine monophosphate cyclohydrolase) (ATIC) [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase) (AICAR formyltransferase) (AICAR transformylase); Inosine 5'-monophosphate cyclohydrolase (IMP cyclohydrolase) (EC 3.5.4.10) (IMP synthase) (Inosinicase)] Gallus gallus (Chicken) 'de novo' IMP biosynthetic process [GO:0006189] GO:0003937; GO:0004643; GO:0005829; GO:0006189; GO:0042803 25703 XM_044328133.1 57 0 169 0 0 Q5RCY5 5.44e-60 Protein asteroid homolog 1 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0004518 25704 XM_044312023.1 46 9 7 10 20 NA NA NA NA NA NA 25705 XM_029337356.2 1850 2205 1276 784 1424 Q6DH02 4.14e-49 Probable 39S ribosomal protein L24, mitochondrial (L24mt) (MRP-L24) Danio rerio (Zebrafish) (Brachydanio rerio) translation [GO:0006412] GO:0003723; GO:0003735; GO:0005739; GO:0005762; GO:0006412 25706 XM_029353519.2 766 654 241 859 401 NA NA NA NA NA NA 25707 XM_044329143.1 125 32 0 42 8 Q8N8E3 0 Centrosomal protein of 112 kDa (Cep112) (Coiled-coil domain-containing protein 46) Homo sapiens (Human) receptor localization to synapse [GO:0097120] GO:0005737; GO:0005813; GO:0005886; GO:0060077; GO:0097120 25708 XM_029349822.2 1063 549 538 1122 1111 P59511 0 A disintegrin and metalloproteinase with thrombospondin motifs 20 (ADAM-TS 20) (ADAM-TS20) (ADAMTS-20) (EC 3.4.24.-) Mus musculus (Mouse) apoptotic process [GO:0006915]; extracellular matrix organization [GO:0030198]; melanocyte differentiation [GO:0030318]; negative regulation of apoptotic process [GO:0043066]; positive regulation of melanocyte differentiation [GO:0045636]; positive regulation of signal transduction [GO:0009967]; proteolysis [GO:0006508]; regulation of developmental pigmentation [GO:0048070]; signal transduction [GO:0007165] GO:0004175; GO:0004222; GO:0005615; GO:0006508; GO:0006915; GO:0007165; GO:0008270; GO:0009967; GO:0030198; GO:0030318; GO:0031012; GO:0043066; GO:0045636; GO:0048070 25709 XM_029349822.2 1063 549 538 1122 1111 P59511 1.47e-149 A disintegrin and metalloproteinase with thrombospondin motifs 20 (ADAM-TS 20) (ADAM-TS20) (ADAMTS-20) (EC 3.4.24.-) Mus musculus (Mouse) apoptotic process [GO:0006915]; extracellular matrix organization [GO:0030198]; melanocyte differentiation [GO:0030318]; negative regulation of apoptotic process [GO:0043066]; positive regulation of melanocyte differentiation [GO:0045636]; positive regulation of signal transduction [GO:0009967]; proteolysis [GO:0006508]; regulation of developmental pigmentation [GO:0048070]; signal transduction [GO:0007165] GO:0004175; GO:0004222; GO:0005615; GO:0006508; GO:0006915; GO:0007165; GO:0008270; GO:0009967; GO:0030198; GO:0030318; GO:0031012; GO:0043066; GO:0045636; GO:0048070 25710 XM_029349822.2 1063 549 538 1122 1111 P59511 1.64e-84 A disintegrin and metalloproteinase with thrombospondin motifs 20 (ADAM-TS 20) (ADAM-TS20) (ADAMTS-20) (EC 3.4.24.-) Mus musculus (Mouse) apoptotic process [GO:0006915]; extracellular matrix organization [GO:0030198]; melanocyte differentiation [GO:0030318]; negative regulation of apoptotic process [GO:0043066]; positive regulation of melanocyte differentiation [GO:0045636]; positive regulation of signal transduction [GO:0009967]; proteolysis [GO:0006508]; regulation of developmental pigmentation [GO:0048070]; signal transduction [GO:0007165] GO:0004175; GO:0004222; GO:0005615; GO:0006508; GO:0006915; GO:0007165; GO:0008270; GO:0009967; GO:0030198; GO:0030318; GO:0031012; GO:0043066; GO:0045636; GO:0048070 25711 XM_029337154.2 311 188 237 195 188 Q86VD9 6.86e-69 GPI mannosyltransferase 4 (EC 2.4.1.-) (GPI mannosyltransferase IV) (GPI-MT-IV) (Phosphatidylinositol-glycan biosynthesis class Z protein) (PIG-Z) (SMP3 homolog) (hSMP3) Homo sapiens (Human) GPI anchor biosynthetic process [GO:0006506]; preassembly of GPI anchor in ER membrane [GO:0016254] GO:0000026; GO:0000030; GO:0005783; GO:0005789; GO:0006506; GO:0016254 25712 XM_044310182.1 11 52 18 1 0 NA NA NA NA NA NA 25713 XR_003828166.1 150 189 76 67 19 NA NA NA NA NA NA 25714 XM_044328230.1 119 127 143 205 232 Q7TN88 9e-63 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 25715 XM_044328230.1 119 127 143 205 232 Q7TN88 2.8e-55 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 25716 XM_029329213.2 105 253 0 307 0 Q15059 1.17e-102 Bromodomain-containing protein 3 (RING3-like protein) Homo sapiens (Human) chromatin remodeling [GO:0006338]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000785; GO:0003682; GO:0005634; GO:0006338; GO:0006355; GO:0006357; GO:0070577 25717 XM_029329213.2 105 253 0 307 0 Q15059 2.22e-40 Bromodomain-containing protein 3 (RING3-like protein) Homo sapiens (Human) chromatin remodeling [GO:0006338]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000785; GO:0003682; GO:0005634; GO:0006338; GO:0006355; GO:0006357; GO:0070577 25718 XM_029329213.2 105 253 0 307 0 Q15059 4.18e-26 Bromodomain-containing protein 3 (RING3-like protein) Homo sapiens (Human) chromatin remodeling [GO:0006338]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000785; GO:0003682; GO:0005634; GO:0006338; GO:0006355; GO:0006357; GO:0070577 25719 XM_029331260.2 29 32 21 87 12 NA NA NA NA NA NA 25720 XM_044309621.1 17 7 20 2 158 NA NA NA NA NA NA 25721 XM_029328551.2 104 0 0 0 0 NA NA NA NA NA NA 25722 XM_044322154.1 9 0 0 0 0 NA NA NA NA NA NA 25723 XR_006394216.1 1858 1793 5465 5244 873 NA NA NA NA NA NA 25724 XM_044316437.1 1 20 10 1 23 NA NA NA NA NA NA 25725 XM_029336416.2 7501 9990 2536 6798 3744 A7SMR0 2.56e-43 Meiosis expressed gene 1 protein homolog Nematostella vectensis (Starlet sea anemone) NA GO:0005634 25726 XM_044307731.1 397 459 373 342 532 P38942 1.51e-107 4-hydroxybutyrate coenzyme A transferase (EC 2.8.3.-) Clostridium kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680) acetate metabolic process [GO:0006083] GO:0006083; GO:0008775 25727 XM_044307704.1 8 4 0 10 44 B3EX02 4.86e-59 MAM and fibronectin type III domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 25728 XM_029330550.2 37 37 0 0 24 P20911 1.27e-165 Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (40 kDa protein kinase) (CDC2/CDK2,4-activating kinase) (Cell division protein kinase 7) (P40 MO15) Xenopus laevis (African clawed frog) cell division [GO:0051301]; meiotic cell cycle [GO:0051321]; protein phosphorylation [GO:0006468] GO:0004693; GO:0005524; GO:0006468; GO:0008353; GO:0051301; GO:0051321; GO:0070985; GO:0106310 25729 XM_029345896.2 97 0 38 275 244 Q059U7 1.9e-158 Protein inturned (Inturned planar cell polarity effector homolog) (PDZ domain-containing protein 6) Mus musculus (Mouse) cell division [GO:0051301]; cilium assembly [GO:0060271]; embryonic digit morphogenesis [GO:0042733]; establishment of planar polarity [GO:0001736]; hair follicle morphogenesis [GO:0031069]; intraciliary transport [GO:0042073]; keratinocyte differentiation [GO:0030216]; limb development [GO:0060173]; motile cilium assembly [GO:0044458]; negative regulation of cell division [GO:0051782]; negative regulation of keratinocyte proliferation [GO:0010839]; nervous system development [GO:0007399]; neural tube development [GO:0021915]; non-motile cilium assembly [GO:1905515]; positive regulation of smoothened signaling pathway [GO:0045880]; protein localization to organelle [GO:0033365]; regulation of cilium assembly [GO:1902017]; regulation of ossification [GO:0030278]; regulation of smoothened signaling pathway [GO:0008589]; roof of mouth development [GO:0060021]; smoothened signaling pathway [GO:0007224]; spinal cord dorsal/ventral patterning [GO:0021513]; tongue morphogenesis [GO:0043587]; vesicle-mediated transport [GO:0016192] GO:0001736; GO:0005737; GO:0005814; GO:0005929; GO:0007224; GO:0007399; GO:0008589; GO:0009986; GO:0010839; GO:0016192; GO:0021513; GO:0021915; GO:0030216; GO:0030278; GO:0031069; GO:0031514; GO:0033365; GO:0035869; GO:0036064; GO:0042073; GO:0042733; GO:0043587; GO:0044458; GO:0045880; GO:0051301; GO:0051782; GO:0060021; GO:0060173; GO:0060271; GO:1902017; GO:1905515 25730 XM_044310050.1 0 19 0 0 0 NA NA NA NA NA NA 25731 XR_006397167.1 0 0 0 0 15 NA NA NA NA NA NA 25732 XM_044315318.1 0 45 0 0 2 NA NA NA NA NA NA 25733 XM_044310841.1 145 155 170 163 115 Q7RTR2 2.52e-54 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 25734 XM_044310841.1 145 155 170 163 115 Q7RTR2 2.73e-40 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 25735 XM_029324481.2 1 6 0 9 11 NA NA NA NA NA NA 25736 XM_044307493.1 11 7 0 3 5 P79385 1.41e-26 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (SED1) (Sperm surface protein SP47) (PP47) Sus scrofa (Pig) angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; single fertilization [GO:0007338] GO:0001525; GO:0002080; GO:0005576; GO:0007155; GO:0007338 25737 XM_044321554.1 56 0 0 13 18 NA NA NA NA NA NA 25738 XM_029342480.2 51 68 107 131 100 NA NA NA NA NA NA 25739 XR_006394317.1 150 5 44 43 154 NA NA NA NA NA NA 25740 XM_044315307.1 20 0 0 457 76 O43290 1.68e-64 U4/U6.U5 tri-snRNP-associated protein 1 (SNU66 homolog) (hSnu66) (Squamous cell carcinoma antigen recognized by T-cells 1) (SART-1) (hSART-1) (U4/U6.U5 tri-snRNP-associated 110 kDa protein) (allergen Hom s 1) Homo sapiens (Human) maturation of 5S rRNA [GO:0000481]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of cytotoxic T cell differentiation [GO:0045585]; spliceosomal snRNP assembly [GO:0000387] GO:0000387; GO:0000398; GO:0000481; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0005794; GO:0005829; GO:0015030; GO:0016607; GO:0045292; GO:0045585; GO:0046540; GO:0071005; GO:0071013 25741 XM_044315307.1 20 0 0 457 76 O43290 1.08e-34 U4/U6.U5 tri-snRNP-associated protein 1 (SNU66 homolog) (hSnu66) (Squamous cell carcinoma antigen recognized by T-cells 1) (SART-1) (hSART-1) (U4/U6.U5 tri-snRNP-associated 110 kDa protein) (allergen Hom s 1) Homo sapiens (Human) maturation of 5S rRNA [GO:0000481]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of cytotoxic T cell differentiation [GO:0045585]; spliceosomal snRNP assembly [GO:0000387] GO:0000387; GO:0000398; GO:0000481; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0005794; GO:0005829; GO:0015030; GO:0016607; GO:0045292; GO:0045585; GO:0046540; GO:0071005; GO:0071013 25742 XM_029336478.2 863 403 431 973 951 Q26486 6.23e-33 46 kDa FK506-binding nuclear protein (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Spodoptera frugiperda (Fall armyworm) NA GO:0003677; GO:0003755; GO:0005634 25743 XM_029336478.2 863 403 431 973 951 Q26486 1.71e-22 46 kDa FK506-binding nuclear protein (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Spodoptera frugiperda (Fall armyworm) NA GO:0003677; GO:0003755; GO:0005634 25744 XM_029345374.2 0 4 11 5 10 A2RTF1 8.36e-32 Cation channel sperm-associated auxiliary subunit beta (CatSper-beta) Mus musculus (Mouse) sperm capacitation [GO:0048240] GO:0005929; GO:0034702; GO:0036128; GO:0048240; GO:0097228 25745 XM_044324925.1 0 0 0 17 0 Q80ZX8 6.99e-93 Sperm-associated antigen 1 (Infertility-related sperm protein Spag-1) (TPR-containing protein involved in spermatogenesis) (TPIS) Mus musculus (Mouse) axonemal dynein complex assembly [GO:0070286]; single fertilization [GO:0007338] GO:0005525; GO:0005737; GO:0005829; GO:0007338; GO:0016787; GO:0070286; GO:0101031; GO:0120293 25746 XM_044324132.1 50 5 36 4 245 NA NA NA NA NA NA 25747 XM_044320266.1 67 28 26 21 42 B3EWY9 6.23e-44 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 25748 XM_029344984.2 1457 1037 612 1830 1726 Q8NF64 7.82e-140 Zinc finger MIZ domain-containing protein 2 (PIAS-like protein Zimp7) Homo sapiens (Human) positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0005634; GO:0005654; GO:0005739; GO:0006357; GO:0008270; GO:0030374; GO:0043596; GO:0045944 25749 XM_029350968.2 931 517 465 663 504 Q08DH3 1.75e-52 Probable tRNA methyltransferase 9B (Probable tRNA methyltransferase 9-like protein) (EC 2.1.1.-) Bos taurus (Bovine) tRNA methylation [GO:0030488]; tRNA wobble uridine modification [GO:0002098] GO:0000049; GO:0002098; GO:0005634; GO:0005737; GO:0030488; GO:0106335 25750 XM_029339092.2 16 0 0 21 0 P27590 9.57e-33 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Rattus norvegicus (Rat) antibacterial innate immune response [GO:0140367]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; autophagy [GO:0006914]; calcium ion homeostasis [GO:0055074]; cellular calcium ion homeostasis [GO:0006874]; cellular chloride ion homeostasis [GO:0030644]; cellular phosphate ion homeostasis [GO:0030643]; cellular response to unfolded protein [GO:0034620]; cellular sodium ion homeostasis [GO:0006883]; chaperone-mediated protein folding [GO:0061077]; chemical homeostasis [GO:0048878]; chloride ion homeostasis [GO:0055064]; citric acid secretion [GO:0046720]; collecting duct development [GO:0072044]; connective tissue replacement [GO:0097709]; creatinine homeostasis [GO:0097273]; defense response to Gram-negative bacterium [GO:0050829]; endoplasmic reticulum organization [GO:0007029]; gene expression [GO:0010467]; glomerular filtration [GO:0003094]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; ion homeostasis [GO:0050801]; juxtaglomerular apparatus development [GO:0072051]; kidney development [GO:0001822]; leukocyte cell-cell adhesion [GO:0007159]; lipid metabolic process [GO:0006629]; loop of Henle development [GO:0072070]; metanephric ascending thin limb development [GO:0072218]; metanephric distal convoluted tubule development [GO:0072221]; metanephric thick ascending limb development [GO:0072233]; micturition [GO:0060073]; multicellular organismal homeostasis [GO:0048871]; multicellular organismal response to stress [GO:0033555]; neutrophil migration [GO:1990266]; organ or tissue specific immune response [GO:0002251]; peptidyl-threonine phosphorylation [GO:0018107]; phosphate ion homeostasis [GO:0055062]; potassium ion homeostasis [GO:0055075]; protein localization to vacuole [GO:0072665]; protein phosphorylation [GO:0006468]; protein transport into plasma membrane raft [GO:0044861]; regulation of blood pressure [GO:0008217]; regulation of protein transport [GO:0051223]; regulation of urine volume [GO:0035809]; renal sodium ion absorption [GO:0070294]; renal urate salt excretion [GO:0097744]; renal water homeostasis [GO:0003091]; response to endoplasmic reticulum stress [GO:0034976]; response to lipopolysaccharide [GO:0032496]; response to organic substance [GO:0010033]; response to unfolded protein [GO:0006986]; response to water deprivation [GO:0009414]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; sodium ion homeostasis [GO:0055078]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; ubiquitin-dependent ERAD pathway [GO:0030433]; urate transport [GO:0015747]; urea transmembrane transport [GO:0071918]; water homeostasis [GO:0030104] GO:0000922; GO:0001822; GO:0002251; GO:0003091; GO:0003094; GO:0005201; GO:0005509; GO:0005615; GO:0005783; GO:0005794; GO:0005886; GO:0005929; GO:0006468; GO:0006629; GO:0006874; GO:0006883; GO:0006914; GO:0006915; GO:0006954; GO:0006986; GO:0007029; GO:0007157; GO:0007159; GO:0008217; GO:0008380; GO:0009410; GO:0009414; GO:0009986; GO:0010033; GO:0010467; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0018107; GO:0019864; GO:0030104; GO:0030433; GO:0030643; GO:0030644; GO:0031410; GO:0032496; GO:0033209; GO:0033555; GO:0034620; GO:0034976; GO:0035809; GO:0044861; GO:0045121; GO:0045177; GO:0046720; GO:0048871; GO:0048878; GO:0050801; GO:0050829; GO:0051223; GO:0055062; GO:0055064; GO:0055074; GO:0055075; GO:0055078; GO:0060073; GO:0060170; GO:0061077; GO:0070294; GO:0071918; GO:0072044; GO:0072051; GO:0072070; GO:0072218; GO:0072221; GO:0072233; GO:0072665; GO:0097190; GO:0097273; GO:0097709; GO:0097744; GO:0140367; GO:1990266 25751 XM_029355050.2 0 6 0 5 8 NA NA NA NA NA NA 25752 XM_044309251.1 14 0 25 1 28 NA NA NA NA NA NA 25753 XM_044311836.1 39 0 0 96 20 Q5EA28 6.09e-52 CXXC-type zinc finger protein 1 (CpG-binding protein) (PHD finger and CXXC domain-containing protein 1) Bos taurus (Bovine) histone H3-K4 methylation [GO:0051568]; positive regulation of DNA-templated transcription [GO:0045893] GO:0005634; GO:0005829; GO:0008270; GO:0016363; GO:0016607; GO:0035064; GO:0045322; GO:0045893; GO:0048188; GO:0051568 25754 XM_044326317.1 705 382 299 429 669 Q8TD16 2.3e-127 Protein bicaudal D homolog 2 (Bic-D 2) Homo sapiens (Human) centrosome localization [GO:0051642]; microtubule anchoring at microtubule organizing center [GO:0072393]; microtubule-based movement [GO:0007018]; minus-end-directed organelle transport along microtubule [GO:0072385]; mRNA transport [GO:0051028]; protein localization to Golgi apparatus [GO:0034067]; protein localization to organelle [GO:0033365]; protein transport [GO:0015031]; regulation of microtubule cytoskeleton organization [GO:0070507]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] GO:0005635; GO:0005642; GO:0005643; GO:0005737; GO:0005794; GO:0005813; GO:0005829; GO:0005886; GO:0006890; GO:0007018; GO:0008093; GO:0015031; GO:0031267; GO:0031410; GO:0033365; GO:0034067; GO:0034452; GO:0051028; GO:0051642; GO:0051959; GO:0070507; GO:0070840; GO:0072385; GO:0072393 25755 XM_044323541.1 0 29 24 0 0 NA NA NA NA NA NA 25756 XR_006392279.1 31 12 7 12 0 NA NA NA NA NA NA 25757 XM_044316530.1 8 17 16 17 48 NA NA NA NA NA NA 25758 XM_044311465.1 0 0 0 128 154 E9QBI7 3.95e-51 Metalloendopeptidase OMA1, mitochondrial (zfoma1) (EC 3.4.24.-) (Overlapping with the m-AAA protease 1 homolog) Danio rerio (Zebrafish) (Brachydanio rerio) diet induced thermogenesis [GO:0002024]; energy homeostasis [GO:0097009]; glucose metabolic process [GO:0006006]; HRI-mediated signaling [GO:0140468]; integrated stress response signaling [GO:0140467]; lipid metabolic process [GO:0006629]; mitochondrial protein processing [GO:0034982]; mitochondrial respiratory chain complex assembly [GO:0033108]; negative regulation of mitochondrial fusion [GO:0010637]; positive regulation of apoptotic process [GO:0043065]; protein autoprocessing [GO:0016540]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of cristae formation [GO:1903850]; zymogen activation [GO:0031638] GO:0002024; GO:0004222; GO:0005743; GO:0006006; GO:0006515; GO:0006629; GO:0010637; GO:0016020; GO:0016540; GO:0031638; GO:0031966; GO:0033108; GO:0034982; GO:0043065; GO:0046872; GO:0051603; GO:0097009; GO:0140467; GO:0140468; GO:1903850 25759 XM_029357585.2 2727 1921 1080 2124 1900 Q9UBV8 8.1e-52 Peflin (PEF protein with a long N-terminal hydrophobic domain) (Penta-EF hand domain-containing protein 1) Homo sapiens (Human) COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; positive regulation of protein monoubiquitination [GO:1902527]; response to calcium ion [GO:0051592] GO:0003723; GO:0005509; GO:0005737; GO:0005783; GO:0006888; GO:0014029; GO:0014032; GO:0030127; GO:0031463; GO:0042802; GO:0046982; GO:0046983; GO:0048208; GO:0048306; GO:0051592; GO:0070062; GO:1902527; GO:1990756 25760 XM_029332493.2 3850 2457 1617 2340 2775 Q4R562 7.38e-152 Beta-arrestin-1 (Arrestin beta-1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) negative regulation of Notch signaling pathway [GO:0045746]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; protein transport [GO:0015031]; signal transduction [GO:0007165]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0001934; GO:0002092; GO:0005634; GO:0005905; GO:0006511; GO:0007165; GO:0015031; GO:0031143; GO:0031410; GO:0045746 25761 XM_044327575.1 370 2 29 5 1 NA NA NA NA NA NA 25762 XM_044315401.1 22 22 0 1 119 NA NA NA NA NA NA 25763 XM_029328938.2 44135 60701 25647 46901 35121 P14211 8.07e-125 Calreticulin (CRP55) (Calregulin) (Endoplasmic reticulum resident protein 60) (ERp60) (HACBP) Mus musculus (Mouse) cardiac muscle cell differentiation [GO:0055007]; cellular response to electrical stimulus [GO:0071257]; cellular response to lithium ion [GO:0071285]; cellular response to organic substance [GO:0071310]; cellular response to virus [GO:0098586]; cellular senescence [GO:0090398]; cortical actin cytoskeleton organization [GO:0030866]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of retinoic acid receptor signaling pathway [GO:0048387]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of translation [GO:0017148]; negative regulation of trophoblast cell migration [GO:1901164]; peptide antigen assembly with MHC class I protein complex [GO:0002502]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of gene expression [GO:0010628]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of phagocytosis [GO:0050766]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein export from nucleus [GO:0006611]; protein folding [GO:0006457]; protein localization to nucleus [GO:0034504]; protein stabilization [GO:0050821]; regulation of meiotic nuclear division [GO:0040020]; response to estradiol [GO:0032355]; response to glycoside [GO:1903416]; response to testosterone [GO:0033574]; response to xenobiotic stimulus [GO:0009410]; selective autophagy [GO:0061912]; spermatogenesis [GO:0007283]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0000122; GO:0001669; GO:0002502; GO:0003729; GO:0005178; GO:0005506; GO:0005509; GO:0005576; GO:0005615; GO:0005634; GO:0005635; GO:0005737; GO:0005783; GO:0005788; GO:0005789; GO:0005790; GO:0005794; GO:0005829; GO:0005844; GO:0005886; GO:0006457; GO:0006611; GO:0007283; GO:0008284; GO:0009410; GO:0009897; GO:0009986; GO:0010595; GO:0010628; GO:0016020; GO:0016529; GO:0017148; GO:0030246; GO:0030433; GO:0030866; GO:0031625; GO:0032355; GO:0032991; GO:0033018; GO:0033144; GO:0033574; GO:0034504; GO:0040020; GO:0042277; GO:0042562; GO:0042824; GO:0043231; GO:0044194; GO:0044322; GO:0045335; GO:0045665; GO:0045787; GO:0045892; GO:0048387; GO:0048471; GO:0050681; GO:0050766; GO:0050821; GO:0051082; GO:0055007; GO:0060473; GO:0061912; GO:0062023; GO:0071257; GO:0071285; GO:0071310; GO:0090398; GO:0098586; GO:1900026; GO:1901164; GO:1901224; GO:1903416; GO:2000510 25764 XM_044313139.1 376 196 8 248 20 A2AJ76 2.72e-71 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 25765 XM_044313139.1 376 196 8 248 20 A2AJ76 2.45e-63 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 25766 XM_044313139.1 376 196 8 248 20 A2AJ76 5.72e-63 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 25767 XM_044313139.1 376 196 8 248 20 A2AJ76 2e-62 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 25768 XM_044313139.1 376 196 8 248 20 A2AJ76 6.7e-59 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 25769 XM_044313139.1 376 196 8 248 20 A2AJ76 2.8e-58 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 25770 XM_044313139.1 376 196 8 248 20 A2AJ76 1.49e-54 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 25771 XM_044313139.1 376 196 8 248 20 A2AJ76 2.5e-52 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 25772 XM_044313139.1 376 196 8 248 20 A2AJ76 2.2e-51 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 25773 XM_044313139.1 376 196 8 248 20 A2AJ76 4.75e-50 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 25774 XM_044313139.1 376 196 8 248 20 A2AJ76 4.33e-49 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 25775 XM_044313139.1 376 196 8 248 20 A2AJ76 2.51e-46 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 25776 XM_044313139.1 376 196 8 248 20 A2AJ76 1.32e-45 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 25777 XM_044313139.1 376 196 8 248 20 A2AJ76 1.22e-44 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 25778 XM_044313139.1 376 196 8 248 20 A2AJ76 4.59e-44 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 25779 XM_044313139.1 376 196 8 248 20 A2AJ76 8.93e-44 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 25780 XM_044313139.1 376 196 8 248 20 A2AJ76 4.86e-27 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 25781 XM_044321561.1 0 4 25 19 36 NA NA NA NA NA NA 25782 XM_029337026.2 41 25 104 34 146 NA NA NA NA NA NA 25783 XM_029345894.2 0 0 0 179 97 Q059U7 4.76e-158 Protein inturned (Inturned planar cell polarity effector homolog) (PDZ domain-containing protein 6) Mus musculus (Mouse) cell division [GO:0051301]; cilium assembly [GO:0060271]; embryonic digit morphogenesis [GO:0042733]; establishment of planar polarity [GO:0001736]; hair follicle morphogenesis [GO:0031069]; intraciliary transport [GO:0042073]; keratinocyte differentiation [GO:0030216]; limb development [GO:0060173]; motile cilium assembly [GO:0044458]; negative regulation of cell division [GO:0051782]; negative regulation of keratinocyte proliferation [GO:0010839]; nervous system development [GO:0007399]; neural tube development [GO:0021915]; non-motile cilium assembly [GO:1905515]; positive regulation of smoothened signaling pathway [GO:0045880]; protein localization to organelle [GO:0033365]; regulation of cilium assembly [GO:1902017]; regulation of ossification [GO:0030278]; regulation of smoothened signaling pathway [GO:0008589]; roof of mouth development [GO:0060021]; smoothened signaling pathway [GO:0007224]; spinal cord dorsal/ventral patterning [GO:0021513]; tongue morphogenesis [GO:0043587]; vesicle-mediated transport [GO:0016192] GO:0001736; GO:0005737; GO:0005814; GO:0005929; GO:0007224; GO:0007399; GO:0008589; GO:0009986; GO:0010839; GO:0016192; GO:0021513; GO:0021915; GO:0030216; GO:0030278; GO:0031069; GO:0031514; GO:0033365; GO:0035869; GO:0036064; GO:0042073; GO:0042733; GO:0043587; GO:0044458; GO:0045880; GO:0051301; GO:0051782; GO:0060021; GO:0060173; GO:0060271; GO:1902017; GO:1905515 25784 XM_044314770.1 130 236 105 286 220 P20664 2.13e-162 DNA primase small subunit (EC 2.7.7.102) (DNA primase 49 kDa subunit) (p49) Mus musculus (Mouse) DNA replication initiation [GO:0006270]; DNA replication, synthesis of RNA primer [GO:0006269] GO:0000287; GO:0003896; GO:0005658; GO:0006269; GO:0006270; GO:0008270; GO:0032553 25785 XM_044307747.1 75 54 38 5 1 NA NA NA NA NA NA 25786 XR_006396660.1 25 0 48 3 71 NA NA NA NA NA NA 25787 XM_044319997.1 379 283 266 232 312 Q8TB40 1.89e-118 (Lyso)-N-acylphosphatidylethanolamine lipase (EC 3.1.1.-) (Alpha/beta hydrolase domain-containing protein 4) (Abhydrolase domain-containing protein 4) (Alpha/beta-hydrolase 4) Homo sapiens (Human) lipid catabolic process [GO:0016042]; lipid homeostasis [GO:0055088]; N-acylphosphatidylethanolamine metabolic process [GO:0070292]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152] GO:0004622; GO:0005739; GO:0005789; GO:0005811; GO:0006654; GO:0016042; GO:0016787; GO:0036152; GO:0042171; GO:0055088; GO:0070292 25788 XM_044324472.1 406 0 0 1 1 NA NA NA NA NA NA 25789 XM_029344659.2 365 375 229 300 386 Q7ZT01 6.04e-57 DNA replication complex GINS protein PSF3 (GINS complex subunit 3) Xenopus laevis (African clawed frog) DNA replication [GO:0006260] GO:0000811; GO:0003682; GO:0006260; GO:0071162 25790 XR_006393065.1 41 2 25 5 151 NA NA NA NA NA NA 25791 XM_029355390.2 87 87 95 147 56 NA NA NA NA NA NA 25792 XM_044325712.1 389 293 460 597 134 O60266 0 Adenylate cyclase type 3 (EC 4.6.1.1) (ATP pyrophosphate-lyase 3) (Adenylate cyclase type III) (AC-III) (Adenylate cyclase, olfactive type) (Adenylyl cyclase 3) (AC3) Homo sapiens (Human) acrosome reaction [GO:0007340]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cAMP biosynthetic process [GO:0006171]; cellular response to forskolin [GO:1904322]; flagellated sperm motility [GO:0030317]; intracellular signal transduction [GO:0035556]; olfactory learning [GO:0008355]; sensory perception of smell [GO:0007608]; signal transduction [GO:0007165]; single fertilization [GO:0007338] GO:0004016; GO:0005516; GO:0005524; GO:0005737; GO:0005794; GO:0005886; GO:0005929; GO:0006171; GO:0007165; GO:0007189; GO:0007338; GO:0007340; GO:0007608; GO:0008355; GO:0016020; GO:0030317; GO:0035556; GO:0046872; GO:0060170; GO:1904322 25793 XR_006397713.1 12 0 0 5 0 NA NA NA NA NA NA 25794 XM_029328368.2 0 0 9 27 24 NA NA NA NA NA NA 25795 XM_029325118.2 1229 1062 1034 1095 1360 P97588 0 Mothers against decapentaplegic homolog 1 (MAD homolog 1) (Mothers against DPP homolog 1) (SMAD family member 1) (SMAD 1) (Smad1) Rattus norvegicus (Rat) anatomical structure morphogenesis [GO:0009653]; BMP signaling pathway [GO:0030509]; bone development [GO:0060348]; cardiac muscle cell proliferation [GO:0060038]; cartilage development [GO:0051216]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to BMP stimulus [GO:0071773]; cellular response to organic cyclic compound [GO:0071407]; DNA-templated transcription [GO:0006351]; embryonic pattern specification [GO:0009880]; gamete generation [GO:0007276]; hindbrain development [GO:0030902]; homeostatic process [GO:0042592]; inflammatory response [GO:0006954]; kidney development [GO:0001822]; MAPK cascade [GO:0000165]; mesodermal cell fate commitment [GO:0001710]; midbrain development [GO:0030901]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of muscle cell differentiation [GO:0051148]; osteoblast differentiation [GO:0001649]; osteoblast fate commitment [GO:0002051]; positive regulation of cartilage development [GO:0061036]; positive regulation of cell differentiation [GO:0045597]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of gene expression [GO:0010628]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; protein phosphorylation [GO:0006468]; regulation of transcription by RNA polymerase II [GO:0006357]; response to organonitrogen compound [GO:0010243]; response to xenobiotic stimulus [GO:0009410]; SMAD protein complex assembly [GO:0007183]; SMAD protein signal transduction [GO:0060395]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ureteric bud development [GO:0001657]; wound healing [GO:0042060] GO:0000165; GO:0000978; GO:0000981; GO:0001228; GO:0001649; GO:0001657; GO:0001710; GO:0001822; GO:0002051; GO:0003700; GO:0005634; GO:0005637; GO:0005667; GO:0005737; GO:0006351; GO:0006357; GO:0006366; GO:0006468; GO:0006954; GO:0007179; GO:0007183; GO:0007276; GO:0008283; GO:0008285; GO:0009410; GO:0009653; GO:0009880; GO:0010243; GO:0010628; GO:0010656; GO:0017151; GO:0019901; GO:0030154; GO:0030509; GO:0030901; GO:0030902; GO:0032991; GO:0042060; GO:0042592; GO:0042802; GO:0043565; GO:0045597; GO:0045669; GO:0045944; GO:0046872; GO:0050775; GO:0051148; GO:0051216; GO:0060038; GO:0060348; GO:0060395; GO:0061036; GO:0070410; GO:0070411; GO:0070878; GO:0071142; GO:0071144; GO:0071407; GO:0071773; GO:1901522; GO:1902895; GO:1903672 25796 XM_029328315.2 75 41 114 0 0 NA NA NA NA NA NA 25797 XM_029329697.2 24 35 0 0 11 NA NA NA NA NA NA 25798 XM_044319019.1 199 0 2 56 100 Q09328 2.55e-131 Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (EC 2.4.1.155) (Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase V) (GlcNAc-T V) (GNT-V) (Mannoside acetylglucosaminyltransferase 5) (N-acetylglucosaminyl-transferase V) [Cleaved into: Secreted alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (Secreted beta-1,6-N-acetylglucosaminyltransferase V) (Secreted GNT-V)] Homo sapiens (Human) negative regulation of protein tyrosine phosphatase activity [GO:1903614]; positive regulation of cell migration [GO:0030335]; positive regulation of receptor signaling pathway via STAT [GO:1904894]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279]; viral protein processing [GO:0019082] GO:0000139; GO:0004864; GO:0005794; GO:0006487; GO:0016020; GO:0018279; GO:0019082; GO:0030144; GO:0030145; GO:0030335; GO:0070062; GO:1903614; GO:1904894 25799 XM_029352485.2 0 27 0 48 0 Q6VVW5 9.18e-77 Atrial natriuretic peptide receptor 2 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type B) (ANP-B) (ANPR-B) (NPR-B) (Guanylate cyclase B) (GC-B) Mus musculus (Mouse) activation of meiosis involved in egg activation [GO:0060466]; axonogenesis [GO:0007409]; axonogenesis involved in innervation [GO:0060385]; blood circulation [GO:0008015]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; bone development [GO:0060348]; bone growth [GO:0098868]; c-di-GMP signaling [GO:0061939]; cartilage development [GO:0051216]; cellular response to cGMP [GO:0071321]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to peptide [GO:1901653]; cGMP biosynthetic process [GO:0006182]; cGMP metabolic process [GO:0046068]; cGMP-mediated signaling [GO:0019934]; chemical synaptic transmission [GO:0007268]; chondrocyte differentiation [GO:0002062]; chondrocyte proliferation [GO:0035988]; chromosome organization [GO:0051276]; collateral sprouting [GO:0048668]; cumulus cell differentiation [GO:0001549]; digestive tract development [GO:0048565]; digestive tract morphogenesis [GO:0048546]; endochondral ossification [GO:0001958]; epidermal growth factor receptor signaling pathway [GO:0007173]; execution phase of apoptosis [GO:0097194]; female genitalia development [GO:0030540]; gastric emptying [GO:0035483]; genitalia morphogenesis [GO:0035112]; germ cell development [GO:0007281]; growth plate cartilage development [GO:0003417]; limb development [GO:0060173]; limb morphogenesis [GO:0035108]; lymph vessel development [GO:0001945]; MAPK cascade [GO:0000165]; meiotic cell cycle [GO:0051321]; meiotic cell cycle process involved in oocyte maturation [GO:1903537]; multicellular organism growth [GO:0035264]; multicellular organism reproduction [GO:0032504]; negative regulation of meiotic cell cycle [GO:0051447]; negative regulation of oocyte maturation [GO:1900194]; nerve development [GO:0021675]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; oocyte development [GO:0048599]; ovarian follicle development [GO:0001541]; positive regulation of cGMP-mediated signaling [GO:0010753]; post-anal tail morphogenesis [GO:0036342]; protein phosphorylation [GO:0006468]; receptor guanylyl cyclase signaling pathway [GO:0007168]; reproductive process [GO:0022414]; response to fibroblast growth factor [GO:0071774]; response to hormone [GO:0009725]; response to luteinizing hormone [GO:0034699]; response to salt [GO:1902074]; response to wounding [GO:0009611]; sensory perception of sound [GO:0007605]; signal transduction [GO:0007165]; single fertilization [GO:0007338]; smooth muscle tissue development [GO:0048745]; spermatogenesis [GO:0007283]; startle response [GO:0001964]; vacuole organization [GO:0007033]; vascular wound healing [GO:0061042]; vasculogenesis [GO:0001570]; vestibulocochlear nerve development [GO:0021562]; vestibulocochlear nerve maturation [GO:0021647]; white fat cell differentiation [GO:0050872] GO:0000165; GO:0001541; GO:0001549; GO:0001568; GO:0001570; GO:0001653; GO:0001945; GO:0001958; GO:0001964; GO:0001974; GO:0002062; GO:0003417; GO:0004383; GO:0004672; GO:0005524; GO:0005525; GO:0005634; GO:0005737; GO:0005886; GO:0005929; GO:0006182; GO:0006468; GO:0007033; GO:0007165; GO:0007168; GO:0007173; GO:0007268; GO:0007281; GO:0007283; GO:0007338; GO:0007409; GO:0007605; GO:0008015; GO:0009611; GO:0009725; GO:0010753; GO:0016941; GO:0017046; GO:0019228; GO:0019934; GO:0021562; GO:0021647; GO:0021675; GO:0022414; GO:0030540; GO:0032504; GO:0034699; GO:0035108; GO:0035112; GO:0035264; GO:0035483; GO:0035988; GO:0036342; GO:0042562; GO:0042802; GO:0043005; GO:0045202; GO:0046068; GO:0048546; GO:0048565; GO:0048599; GO:0048668; GO:0048745; GO:0050872; GO:0051216; GO:0051276; GO:0051321; GO:0051402; GO:0051447; GO:0060173; GO:0060348; GO:0060385; GO:0060466; GO:0061042; GO:0061939; GO:0071321; GO:0071774; GO:0097011; GO:0097194; GO:0098868; GO:1900194; GO:1901653; GO:1902074; GO:1903537 25800 XM_029337297.2 107 26 62 68 209 B4E2M5 3.25e-29 Ankyrin repeat domain-containing protein 66 Homo sapiens (Human) NA NA 25801 XR_006395776.1 22 70 19 47 57 NA NA NA NA NA NA 25802 XM_029337813.2 903 526 442 421 460 Q9BY27 5.68e-38 Protein DGCR6L (DiGeorge syndrome critical region 6-like protein) Homo sapiens (Human) NA GO:0005634 25803 XR_006392001.1 0 0 33 16 0 NA NA NA NA NA NA 25804 XR_006396920.1 22 8 2 4 5 NA NA NA NA NA NA 25805 XM_044319858.1 0 0 34 0 0 Q8MIQ9 3.98e-125 P protein (Melanocyte-specific transporter protein) (Pink-eyed dilution protein homolog) Sus scrofa (Pig) lysosomal lumen pH elevation [GO:0035752]; melanin biosynthetic process [GO:0042438]; melanin biosynthetic process from tyrosine [GO:0006583]; melanocyte differentiation [GO:0030318] GO:0006583; GO:0030318; GO:0033162; GO:0035752; GO:0042438; GO:0061778 25806 XM_029325027.2 161 178 103 72 296 Q4V8V2 2.84e-52 Nucleoside diphosphate-linked moiety X motif 17 (Nudix motif 17) (EC 3.6.1.-) Danio rerio (Zebrafish) (Brachydanio rerio) NAD catabolic process [GO:0019677]; NADH metabolic process [GO:0006734]; NADP catabolic process [GO:0006742] GO:0005777; GO:0006734; GO:0006742; GO:0019677; GO:0035529; GO:0046872 25807 XM_029328587.2 338 123 94 238 126 Q8UVX8 3.43e-48 Type II iodothyronine deiodinase (EC 1.21.99.4) (5DII) (DIOII) (Type 2 DI) (Type-II 5'-deiodinase) Neoceratodus forsteri (Australian lungfish) (Ceratodus forsteri) hormone biosynthetic process [GO:0042446]; thyroid hormone metabolic process [GO:0042403] GO:0004800; GO:0016020; GO:0042403; GO:0042446 25808 XM_029342641.2 10489 9823 4151 10401 7011 P62832 3.59e-81 60S ribosomal protein L23 Rattus norvegicus (Rat) cellular response to actinomycin D [GO:0072717]; G1 to G0 transition [GO:0070314]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of ubiquitin protein ligase activity [GO:1904667]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of signal transduction by p53 class mediator [GO:1901798]; protein stabilization [GO:0050821]; protein-DNA complex disassembly [GO:0032986]; regulation of G1 to G0 transition [GO:1903450]; translation [GO:0006412] GO:0000122; GO:0001223; GO:0003735; GO:0005654; GO:0005730; GO:0005737; GO:0005840; GO:0006412; GO:0008284; GO:0010628; GO:0014069; GO:0022625; GO:0022626; GO:0031625; GO:0032986; GO:0032991; GO:0045202; GO:0050821; GO:0070180; GO:0070314; GO:0072717; GO:1901798; GO:1903450; GO:1904667; GO:1990948; GO:2000059 25809 XM_029338172.2 0 0 60 32 215 NA NA NA NA NA NA 25810 XM_029341827.2 1028 732 342 829 309 Q2YDN4 1.01e-36 Coiled-coil domain-containing protein 105 Bos taurus (Bovine) NA NA 25811 XM_044328277.1 814 708 537 765 581 Q9D3S3 6.01e-69 Sorting nexin-29 Mus musculus (Mouse) NA GO:0035091 25812 XM_044328277.1 814 708 537 765 581 Q9D3S3 8.99e-56 Sorting nexin-29 Mus musculus (Mouse) NA GO:0035091 25813 XM_044316842.1 368 26 14 77 299 NA NA NA NA NA NA 25814 XM_029347516.2 11 15 6 4 35 NA NA NA NA NA NA 25815 XM_044318894.1 0 0 0 0 8 NA NA NA NA NA NA 25816 XM_029356133.2 1307 509 527 1714 1275 Q9VCA2 3.22e-59 Organic cation transporter protein Drosophila melanogaster (Fruit fly) apoptotic process [GO:0006915]; ion transport [GO:0006811] GO:0006811; GO:0006915; GO:0016020; GO:0022857 25817 XR_006394430.1 61 106 1 2 43 NA NA NA NA NA NA 25818 XM_029349992.2 17 16 1 18 18 NA NA NA NA NA NA 25819 XM_029358071.2 13 1 13 0 28 B7FF09 2.85e-87 WD repeat-containing protein on Y chromosome (WD40 Y) Drosophila willistoni (Fruit fly) NA NA 25820 XM_029351562.2 33 6 40 70 125 NA NA NA NA NA NA 25821 XM_044307357.1 464 175 127 329 403 Q90744 1.01e-146 Alpha-N-acetylgalactosaminidase (EC 3.2.1.49) (Alpha-galactosidase B) Gallus gallus (Chicken) glycoside catabolic process [GO:0016139]; lipid metabolic process [GO:0006629]; oligosaccharide metabolic process [GO:0009311] GO:0004557; GO:0005737; GO:0005764; GO:0006629; GO:0008456; GO:0009311; GO:0016139 25822 XM_044329102.1 20 3 5 0 14 NA NA NA NA NA NA 25823 XM_029323987.2 56 35 24 34 46 Q6IRM9 6.46e-38 Protein zwilch homolog Xenopus laevis (African clawed frog) cell division [GO:0051301]; mitotic spindle assembly checkpoint signaling [GO:0007094] GO:0007094; GO:0051301; GO:1990423 25824 XM_044317747.1 124 0 0 0 65 Q60431 2.32e-34 Caspase-3 (CASP-3) (EC 3.4.22.56) (Apopain) (Cysteine protease CPP32) (CPP-32) (Protein Yama) (SREBP cleavage activity 1) (SCA-1) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12] Mesocricetus auratus (Golden hamster) intracellular signal transduction [GO:0035556]; positive regulation of amyloid-beta formation [GO:1902004]; proteolysis [GO:0006508]; regulation of protein stability [GO:0031647] GO:0004175; GO:0005737; GO:0006508; GO:0031647; GO:0035556; GO:0097153; GO:0097199; GO:0097200; GO:1902004 25825 XM_044315143.1 15 0 17 10 3 NA NA NA NA NA NA 25826 XM_029357550.2 840 484 288 787 592 Q8VCK5 2.08e-153 Kelch-like protein 20 (Kelch-like ECT2-interacting protein) Mus musculus (Mouse) Golgi to endosome transport [GO:0006895]; negative regulation of apoptotic process [GO:0043066]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K33-linked ubiquitination [GO:1990390]; protein transport [GO:0015031]; protein ubiquitination [GO:0016567] GO:0003779; GO:0004842; GO:0005737; GO:0005794; GO:0005802; GO:0005829; GO:0006895; GO:0015031; GO:0016567; GO:0016605; GO:0019964; GO:0030424; GO:0030425; GO:0031463; GO:0043066; GO:0043161; GO:0048471; GO:1990390 25827 XM_029357550.2 840 484 288 787 592 Q8VCK5 3.69e-34 Kelch-like protein 20 (Kelch-like ECT2-interacting protein) Mus musculus (Mouse) Golgi to endosome transport [GO:0006895]; negative regulation of apoptotic process [GO:0043066]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K33-linked ubiquitination [GO:1990390]; protein transport [GO:0015031]; protein ubiquitination [GO:0016567] GO:0003779; GO:0004842; GO:0005737; GO:0005794; GO:0005802; GO:0005829; GO:0006895; GO:0015031; GO:0016567; GO:0016605; GO:0019964; GO:0030424; GO:0030425; GO:0031463; GO:0043066; GO:0043161; GO:0048471; GO:1990390 25828 XR_006392478.1 28 73 48 0 237 NA NA NA NA NA NA 25829 XM_029329339.2 603 249 220 515 564 D4A770 6.3e-134 Protein C12orf4 homolog Rattus norvegicus (Rat) regulation of mast cell degranulation [GO:0043304] GO:0005737; GO:0043304 25830 XM_044321637.1 372 347 205 292 319 Q5EB14 1.49e-26 Sugar transporter SWEET1 (RAG1-activating protein 1) (Solute carrier family 50 member 1) Danio rerio (Zebrafish) (Brachydanio rerio) carbohydrate transport [GO:0008643] GO:0000139; GO:0005886; GO:0008643; GO:0016020; GO:0051119 25831 XM_029338590.2 193 56 31 80 94 NA NA NA NA NA NA 25832 XM_029343751.2 28 1 4 27 358 NA NA NA NA NA NA 25833 XM_029324236.2 375 232 0 324 348 Q5PQ23 6.65e-98 Outer dense fiber protein 2 (Cenexin) (Outer dense fiber of sperm tails protein 2) Xenopus laevis (African clawed frog) cell differentiation [GO:0030154]; spermatogenesis [GO:0007283] GO:0000922; GO:0005737; GO:0005814; GO:0005874; GO:0007283; GO:0030154; GO:0036126 25834 XM_029329495.2 441 344 213 174 258 Q8TAC1 7.25e-32 Rieske domain-containing protein Homo sapiens (Human) NA GO:0046872; GO:0051537 25835 XM_044328518.1 71 91 51 37 72 Q9NVV5 2.23e-41 Androgen-induced gene 1 protein (AIG-1) (Fatty acid esters of hydroxy fatty acids hydrolase AIG1) (FAHFA hydrolase AIG1) (EC 3.1.-.-) Homo sapiens (Human) long-chain fatty acid catabolic process [GO:0042758] GO:0005886; GO:0012505; GO:0016020; GO:0016787; GO:0042758 25836 XR_006391931.1 15 4 65 4 37 NA NA NA NA NA NA 25837 XM_029334660.2 4464 2794 3966 5962 3813 Q95245 8.92e-50 Transmembrane ascorbate-dependent reductase CYB561 (EC 7.2.1.-) (Cytochrome b-561) (Cytochrome b561) Sus scrofa (Pig) ascorbate homeostasis [GO:0140576] GO:0042584; GO:0046872; GO:0140575; GO:0140576 25838 XM_029354195.2 21 156 105 172 58 NA NA NA NA NA NA 25839 XM_029345256.2 3014 1579 2767 1931 3376 NA NA NA NA NA NA 25840 XR_006395571.1 54 19 21 9 0 NA NA NA NA NA NA 25841 XM_044312242.1 117 10 69 56 50 NA NA NA NA NA NA 25842 XM_029335427.2 214 160 180 235 750 Q9NW15 1.67e-58 Anoctamin-10 (Transmembrane protein 16K) Homo sapiens (Human) cation transport [GO:0006812]; chloride transport [GO:0006821]; ion transmembrane transport [GO:0034220]; transmembrane transport [GO:0055085] GO:0005227; GO:0005229; GO:0005886; GO:0006812; GO:0006821; GO:0016020; GO:0034220; GO:0043231; GO:0055085 25843 XR_006391483.1 1147 1150 542 778 369 NA NA NA NA NA NA 25844 XM_044324742.1 64 15 0 18 17 NA NA NA NA NA NA 25845 XM_029328580.2 3989 3022 2844 4129 2439 NA NA NA NA NA NA 25846 XM_044324376.1 11 46 20 29 329 NA NA NA NA NA NA 25847 XM_029344824.2 72 45 27 98 24 A4IF97 6.69e-79 Myosin regulatory light chain 12B (Myosin regulatory light chain 2-B, smooth muscle isoform) (Myosin regulatory light chain 20 kDa) (MLC20) (Myosin regulatory light chain MRLC2) Bos taurus (Bovine) regulation of cell shape [GO:0008360] GO:0001725; GO:0005509; GO:0005737; GO:0005903; GO:0005938; GO:0008360; GO:0016460; GO:0030016; GO:0030018; GO:0032036; GO:0045177 25848 XM_029323960.2 11 0 0 0 0 NA NA NA NA NA NA 25849 XM_029351947.2 0 0 7 2 14 NA NA NA NA NA NA 25850 XM_044325392.1 53 10 2 25 21 NA NA NA NA NA NA 25851 XM_044314603.1 115 71 49 70 120 Q8TD22 1.66e-128 Sideroflexin-5 Homo sapiens (Human) amino acid transport [GO:0006865]; citrate transport [GO:0015746]; mitochondrial transmembrane transport [GO:1990542] GO:0005739; GO:0005743; GO:0006865; GO:0015137; GO:0015746; GO:0022857; GO:1990542 25852 XM_044316170.1 96 108 0 88 36 Q02241 0 Kinesin-like protein KIF23 (Kinesin-like protein 5) (Mitotic kinesin-like protein 1) Homo sapiens (Human) microtubule-based movement [GO:0007018]; mitotic cytokinesis [GO:0000281]; mitotic spindle elongation [GO:0000022]; mitotic spindle midzone assembly [GO:0051256]; positive regulation of cytokinesis [GO:0032467] GO:0000022; GO:0000281; GO:0003777; GO:0005524; GO:0005634; GO:0005654; GO:0005813; GO:0005819; GO:0005829; GO:0005871; GO:0005874; GO:0005925; GO:0007018; GO:0008017; GO:0016887; GO:0030496; GO:0032467; GO:0051256; GO:0072686; GO:0090543; GO:0097149 25853 XM_044318144.1 117 118 55 138 157 NA NA NA NA NA NA 25854 XM_044317485.1 0 0 0 280 0 Q13114 4.47e-99 TNF receptor-associated factor 3 (EC 2.3.2.27) (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein 1) (LAP1) (RING-type E3 ubiquitin transferase TRAF3) Homo sapiens (Human) apoptotic process [GO:0006915]; defense response to virus [GO:0051607]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of JNK cascade [GO:0046330]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of cytokine production [GO:0001817]; regulation of defense response to virus [GO:0050688]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of interferon-beta production [GO:0032648]; regulation of proteolysis [GO:0030162]; signal transduction [GO:0007165]; Toll signaling pathway [GO:0008063]; toll-like receptor signaling pathway [GO:0002224]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; type I interferon-mediated signaling pathway [GO:0060337] GO:0000151; GO:0001817; GO:0002224; GO:0004842; GO:0005164; GO:0005739; GO:0005768; GO:0005829; GO:0006915; GO:0007165; GO:0008063; GO:0008270; GO:0009898; GO:0019901; GO:0019903; GO:0030162; GO:0031625; GO:0031996; GO:0032088; GO:0032648; GO:0033209; GO:0035631; GO:0035666; GO:0042802; GO:0042981; GO:0043122; GO:0046330; GO:0050688; GO:0051607; GO:0060337; GO:0070534; GO:1902554 25855 XM_029326897.2 180 200 267 155 212 O15091 2.2e-25 Mitochondrial ribonuclease P catalytic subunit (EC 3.1.26.5) (Mitochondrial ribonuclease P protein 3) (Mitochondrial RNase P protein 3) (Protein only RNase P catalytic subunit) Homo sapiens (Human) mitochondrial tRNA 5'-end processing [GO:0097745]; tRNA 5'-leader removal [GO:0001682] GO:0001682; GO:0004526; GO:0005654; GO:0005739; GO:0005759; GO:0030678; GO:0042645; GO:0046872; GO:0097745 25856 XR_006391854.1 11 2 4 6 57 NA NA NA NA NA NA 25857 XM_044314585.1 34 3 7 0 3 NA NA NA NA NA NA 25858 XR_003826705.2 24 18 1 13 65 NA NA NA NA NA NA 25859 XM_044307875.1 98 38 0 99 126 Q6P4F7 1.38e-32 Rho GTPase-activating protein 11A (Rho-type GTPase-activating protein 11A) Homo sapiens (Human) positive regulation of GTPase activity [GO:0043547]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] GO:0005096; GO:0005634; GO:0005829; GO:0007165; GO:0043547; GO:0051056 25860 XM_044320979.1 136 112 0 119 118 NA NA NA NA NA NA 25861 XM_044307156.1 46 191 81 318 461 Q9UNS1 1.36e-175 Protein timeless homolog (hTIM) Homo sapiens (Human) branching morphogenesis of an epithelial tube [GO:0048754]; cell cycle phase transition [GO:0044770]; cell division [GO:0051301]; cellular response to bleomycin [GO:1904976]; cellular response to cisplatin [GO:0072719]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hydroxyurea [GO:0072711]; circadian rhythm [GO:0007623]; detection of abiotic stimulus [GO:0009582]; DNA repair [GO:0006281]; DNA replication checkpoint signaling [GO:0000076]; lung development [GO:0030324]; morphogenesis of an epithelium [GO:0002009]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; regulation of circadian rhythm [GO:0042752]; replication fork arrest [GO:0043111]; replication fork protection [GO:0048478] GO:0000076; GO:0000785; GO:0002009; GO:0003677; GO:0005634; GO:0005654; GO:0006281; GO:0006974; GO:0007623; GO:0009582; GO:0030324; GO:0031298; GO:0035861; GO:0042752; GO:0042802; GO:0043111; GO:0044770; GO:0045892; GO:0048478; GO:0048754; GO:0051301; GO:0072711; GO:0072719; GO:1904976; GO:1905168; GO:2000781 25862 XM_044313231.1 48 28 35 13 139 Q3YSJ8 2.55e-157 DNA mismatch repair protein MutS Ehrlichia canis (strain Jake) mismatch repair [GO:0006298] GO:0003684; GO:0005524; GO:0006298; GO:0030983; GO:0140664 25863 XM_029329509.2 8461 5641 3369 5679 3110 Q9QXG4 0 Acetyl-coenzyme A synthetase, cytoplasmic (EC 6.2.1.1) (Acetate--CoA ligase) (Acetyl-CoA synthetase) (ACS) (AceCS) (Acetyl-CoA synthetase 1) (AceCS1) (Acyl-CoA synthetase short-chain family member 2) (Acyl-activating enzyme) (Propionate--CoA ligase) (EC 6.2.1.17) Mus musculus (Mouse) acetate biosynthetic process [GO:0019413]; acetyl-CoA biosynthetic process [GO:0006085]; lipid biosynthetic process [GO:0008610]; propionate biosynthetic process [GO:0019542] GO:0003987; GO:0005524; GO:0005737; GO:0005829; GO:0006085; GO:0008610; GO:0019413; GO:0019542; GO:0050218 25864 XM_044319156.1 136 16 121 338 213 NA NA NA NA NA NA 25865 XM_029355375.2 60 50 48 110 109 Q7SXM0 1.49e-147 Histone deacetylase 8 (HD8) (EC 3.5.1.98) (Protein deacetylase HDAC8) (EC 3.5.1.-) (Protein decrotonylase HDAC8) (EC 3.5.1.-) Danio rerio (Zebrafish) (Brachydanio rerio) central nervous system development [GO:0007417]; chromatin organization [GO:0006325]; histone deacetylation [GO:0016575]; neuron cellular homeostasis [GO:0070050]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000118; GO:0004407; GO:0005694; GO:0005737; GO:0006325; GO:0006357; GO:0007417; GO:0016575; GO:0046872; GO:0070050; GO:0160009 25866 XM_029346443.2 86 78 107 0 258 Q6ZQ11 0 Chondroitin sulfate synthase 1 (EC 2.4.1.175) (EC 2.4.1.226) (Chondroitin glucuronyltransferase 1) (Chondroitin synthase 1) (ChSy-1) (Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1) (N-acetylgalactosaminyltransferase 1) Mus musculus (Mouse) bone morphogenesis [GO:0060349]; cartilage development [GO:0051216]; chondrocyte development [GO:0002063]; chondroitin sulfate biosynthetic process [GO:0030206]; negative regulation of ossification [GO:0030279]; positive regulation of smoothened signaling pathway [GO:0045880]; proximal/distal pattern formation [GO:0009954]; response to nutrient levels [GO:0031667]; sulfation [GO:0051923] GO:0002063; GO:0005576; GO:0005794; GO:0008376; GO:0009954; GO:0016757; GO:0030206; GO:0030279; GO:0031667; GO:0032580; GO:0045880; GO:0046872; GO:0047238; GO:0050510; GO:0051216; GO:0051923; GO:0060349 25867 XM_044329265.1 0 29 10 28 36 NA NA NA NA NA NA 25868 XM_044323226.1 1712 636 472 1416 486 Q91VW5 1.91e-24 Golgin subfamily A member 4 (tGolgin-1) Mus musculus (Mouse) Golgi to plasma membrane protein transport [GO:0043001]; Golgi vesicle transport [GO:0048193]; positive regulation of axon extension [GO:0045773] GO:0000139; GO:0005654; GO:0005737; GO:0005794; GO:0031267; GO:0043001; GO:0045773; GO:0048193; GO:0051020 25869 XM_029348875.2 1107 2674 1350 1919 1430 NA NA NA NA NA NA 25870 XM_044325763.1 25 7 73 14 53 Q5AXT5 4.1e-29 ATP-dependent DNA helicase PIF1 (EC 3.6.4.12) (DNA repair and recombination helicase PIF1) Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; mitochondrial genome maintenance [GO:0000002]; telomere maintenance [GO:0000723] GO:0000002; GO:0000723; GO:0003677; GO:0005524; GO:0005634; GO:0005657; GO:0005739; GO:0006260; GO:0006281; GO:0006310; GO:0016887; GO:0032508; GO:0043139 25871 XM_044313896.1 8 1 0 0 0 NA NA NA NA NA NA 25872 XM_044315228.1 6 0 7 35 29 NA NA NA NA NA NA 25873 XM_044311832.1 3319 1997 1895 3882 3823 A0JMV4 1.32e-72 RNA-binding protein 5-A (RNA-binding motif protein 5-A) Xenopus laevis (African clawed frog) positive regulation of apoptotic process [GO:0043065]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; spliceosomal complex assembly [GO:0000245] GO:0000245; GO:0000381; GO:0003729; GO:0005634; GO:0005681; GO:0043065; GO:0046872 25874 XM_044311832.1 3319 1997 1895 3882 3823 A0JMV4 5.09e-39 RNA-binding protein 5-A (RNA-binding motif protein 5-A) Xenopus laevis (African clawed frog) positive regulation of apoptotic process [GO:0043065]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; spliceosomal complex assembly [GO:0000245] GO:0000245; GO:0000381; GO:0003729; GO:0005634; GO:0005681; GO:0043065; GO:0046872 25875 XM_029333886.2 457 123 463 756 308 NA NA NA NA NA NA 25876 XM_029340296.2 5416 6114 3159 4022 1957 Q8R5H8 1.44e-85 Fas apoptotic inhibitory molecule 1 (rFAIM) Rattus norvegicus (Rat) apoptotic process [GO:0006915]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; positive regulation of neurogenesis [GO:0050769] GO:0005737; GO:0006915; GO:0007249; GO:0050769; GO:1902042 25877 XM_029348524.2 855 358 360 866 478 NA NA NA NA NA NA 25878 XM_029341649.2 42 56 38 66 34 Q9BQP7 1.91e-38 Mitochondrial genome maintenance exonuclease 1 (EC 3.1.-.-) Homo sapiens (Human) mitochondrial DNA repair [GO:0043504]; mitochondrial DNA replication [GO:0006264]; mitochondrial genome maintenance [GO:0000002] GO:0000002; GO:0005739; GO:0006264; GO:0008297; GO:0043504 25879 XM_029357601.2 195 83 105 235 221 Q91XV4 2.94e-103 L-xylulose reductase (XR) (EC 1.1.1.10) (Dicarbonyl/L-xylulose reductase) (Sperm antigen P26h) Mesocricetus auratus (Golden hamster) D-xylose metabolic process [GO:0042732]; glucose metabolic process [GO:0006006]; glucuronate catabolic process to xylulose 5-phosphate [GO:0019640]; NADP metabolic process [GO:0006739]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; xylulose metabolic process [GO:0005997] GO:0001669; GO:0005829; GO:0005881; GO:0005902; GO:0005903; GO:0005997; GO:0006006; GO:0006739; GO:0016020; GO:0016655; GO:0019640; GO:0042732; GO:0042802; GO:0050038; GO:2000379 25880 XM_044317717.1 617 463 373 802 1187 Q64487 8.03e-149 Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48) Mus musculus (Mouse) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; neuron differentiation [GO:0030182]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse assembly [GO:0051965]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; regulation of immune response [GO:0050776]; regulation of postsynaptic density assembly [GO:0099151]; synaptic membrane adhesion [GO:0099560]; trans-synaptic signaling [GO:0099537]; trans-synaptic signaling by trans-synaptic complex [GO:0099545] GO:0004725; GO:0005102; GO:0006470; GO:0007157; GO:0030182; GO:0042734; GO:0046426; GO:0050775; GO:0050776; GO:0050804; GO:0050839; GO:0051965; GO:0097105; GO:0098685; GO:0098686; GO:0098978; GO:0099054; GO:0099151; GO:0099537; GO:0099545; GO:0099560 25881 XM_044319742.1 0 0 11 23 81 NA NA NA NA NA NA 25882 XM_029326958.2 78 8 52 17 190 P27590 1.95e-33 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Rattus norvegicus (Rat) antibacterial innate immune response [GO:0140367]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; autophagy [GO:0006914]; calcium ion homeostasis [GO:0055074]; cellular calcium ion homeostasis [GO:0006874]; cellular chloride ion homeostasis [GO:0030644]; cellular phosphate ion homeostasis [GO:0030643]; cellular response to unfolded protein [GO:0034620]; cellular sodium ion homeostasis [GO:0006883]; chaperone-mediated protein folding [GO:0061077]; chemical homeostasis [GO:0048878]; chloride ion homeostasis [GO:0055064]; citric acid secretion [GO:0046720]; collecting duct development [GO:0072044]; connective tissue replacement [GO:0097709]; creatinine homeostasis [GO:0097273]; defense response to Gram-negative bacterium [GO:0050829]; endoplasmic reticulum organization [GO:0007029]; gene expression [GO:0010467]; glomerular filtration [GO:0003094]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; ion homeostasis [GO:0050801]; juxtaglomerular apparatus development [GO:0072051]; kidney development [GO:0001822]; leukocyte cell-cell adhesion [GO:0007159]; lipid metabolic process [GO:0006629]; loop of Henle development [GO:0072070]; metanephric ascending thin limb development [GO:0072218]; metanephric distal convoluted tubule development [GO:0072221]; metanephric thick ascending limb development [GO:0072233]; micturition [GO:0060073]; multicellular organismal homeostasis [GO:0048871]; multicellular organismal response to stress [GO:0033555]; neutrophil migration [GO:1990266]; organ or tissue specific immune response [GO:0002251]; peptidyl-threonine phosphorylation [GO:0018107]; phosphate ion homeostasis [GO:0055062]; potassium ion homeostasis [GO:0055075]; protein localization to vacuole [GO:0072665]; protein phosphorylation [GO:0006468]; protein transport into plasma membrane raft [GO:0044861]; regulation of blood pressure [GO:0008217]; regulation of protein transport [GO:0051223]; regulation of urine volume [GO:0035809]; renal sodium ion absorption [GO:0070294]; renal urate salt excretion [GO:0097744]; renal water homeostasis [GO:0003091]; response to endoplasmic reticulum stress [GO:0034976]; response to lipopolysaccharide [GO:0032496]; response to organic substance [GO:0010033]; response to unfolded protein [GO:0006986]; response to water deprivation [GO:0009414]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; sodium ion homeostasis [GO:0055078]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; ubiquitin-dependent ERAD pathway [GO:0030433]; urate transport [GO:0015747]; urea transmembrane transport [GO:0071918]; water homeostasis [GO:0030104] GO:0000922; GO:0001822; GO:0002251; GO:0003091; GO:0003094; GO:0005201; GO:0005509; GO:0005615; GO:0005783; GO:0005794; GO:0005886; GO:0005929; GO:0006468; GO:0006629; GO:0006874; GO:0006883; GO:0006914; GO:0006915; GO:0006954; GO:0006986; GO:0007029; GO:0007157; GO:0007159; GO:0008217; GO:0008380; GO:0009410; GO:0009414; GO:0009986; GO:0010033; GO:0010467; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0018107; GO:0019864; GO:0030104; GO:0030433; GO:0030643; GO:0030644; GO:0031410; GO:0032496; GO:0033209; GO:0033555; GO:0034620; GO:0034976; GO:0035809; GO:0044861; GO:0045121; GO:0045177; GO:0046720; GO:0048871; GO:0048878; GO:0050801; GO:0050829; GO:0051223; GO:0055062; GO:0055064; GO:0055074; GO:0055075; GO:0055078; GO:0060073; GO:0060170; GO:0061077; GO:0070294; GO:0071918; GO:0072044; GO:0072051; GO:0072070; GO:0072218; GO:0072221; GO:0072233; GO:0072665; GO:0097190; GO:0097273; GO:0097709; GO:0097744; GO:0140367; GO:1990266 25883 XM_029343929.2 772 452 463 655 889 Q8BX57 1.96e-133 PX domain-containing protein kinase-like protein (Modulator of Na,K-ATPase) (MONaKA) Mus musculus (Mouse) inflammatory response [GO:0006954]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of ATP-dependent activity [GO:0032780]; negative regulation of ion transport [GO:0043271]; protein phosphorylation [GO:0006468] GO:0003779; GO:0004672; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0006468; GO:0006954; GO:0008022; GO:0032780; GO:0032991; GO:0034451; GO:0035091; GO:0043271; GO:0050804 25884 XM_029357987.2 2848 2081 2179 2586 2605 Q5ZLY5 8.47e-108 Pleckstrin homology domain-containing family F member 2 (PH domain-containing family F member 2) Gallus gallus (Chicken) endosome organization [GO:0007032]; endosome to lysosome transport [GO:0008333]; protein transport [GO:0015031] GO:0005769; GO:0005783; GO:0007032; GO:0008333; GO:0015031; GO:0031901; GO:0035091; GO:0046872 25885 XM_044306792.1 962 405 400 817 978 F1RWC3 2.91e-164 Cubilin (Intrinsic factor-cobalamin receptor) Sus scrofa (Pig) cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031] GO:0005509; GO:0005765; GO:0005768; GO:0005905; GO:0008203; GO:0015031; GO:0016324; GO:0031419 25886 XM_044306792.1 962 405 400 817 978 F1RWC3 1.02e-152 Cubilin (Intrinsic factor-cobalamin receptor) Sus scrofa (Pig) cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031] GO:0005509; GO:0005765; GO:0005768; GO:0005905; GO:0008203; GO:0015031; GO:0016324; GO:0031419 25887 XM_044306792.1 962 405 400 817 978 F1RWC3 1.12e-152 Cubilin (Intrinsic factor-cobalamin receptor) Sus scrofa (Pig) cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031] GO:0005509; GO:0005765; GO:0005768; GO:0005905; GO:0008203; GO:0015031; GO:0016324; GO:0031419 25888 XM_044306792.1 962 405 400 817 978 F1RWC3 3.28e-151 Cubilin (Intrinsic factor-cobalamin receptor) Sus scrofa (Pig) cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031] GO:0005509; GO:0005765; GO:0005768; GO:0005905; GO:0008203; GO:0015031; GO:0016324; GO:0031419 25889 XM_044306792.1 962 405 400 817 978 F1RWC3 2.34e-143 Cubilin (Intrinsic factor-cobalamin receptor) Sus scrofa (Pig) cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031] GO:0005509; GO:0005765; GO:0005768; GO:0005905; GO:0008203; GO:0015031; GO:0016324; GO:0031419 25890 XM_044306792.1 962 405 400 817 978 F1RWC3 1.29e-139 Cubilin (Intrinsic factor-cobalamin receptor) Sus scrofa (Pig) cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031] GO:0005509; GO:0005765; GO:0005768; GO:0005905; GO:0008203; GO:0015031; GO:0016324; GO:0031419 25891 XM_044306792.1 962 405 400 817 978 F1RWC3 2.55e-130 Cubilin (Intrinsic factor-cobalamin receptor) Sus scrofa (Pig) cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031] GO:0005509; GO:0005765; GO:0005768; GO:0005905; GO:0008203; GO:0015031; GO:0016324; GO:0031419 25892 XM_044306792.1 962 405 400 817 978 F1RWC3 1.47e-121 Cubilin (Intrinsic factor-cobalamin receptor) Sus scrofa (Pig) cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031] GO:0005509; GO:0005765; GO:0005768; GO:0005905; GO:0008203; GO:0015031; GO:0016324; GO:0031419 25893 XM_044320288.1 0 20 41 26 110 Q29611 7.12e-118 Battenin (Protein CLN3) Canis lupus familiaris (Dog) (Canis familiaris) amyloid precursor protein catabolic process [GO:0042987]; autophagosome-lysosome fusion [GO:0061909]; cellular water homeostasis [GO:0009992]; glycerophospholipid biosynthetic process [GO:0046474]; glycolipid transport [GO:0046836]; Golgi to lysosome transport [GO:0090160]; L-arginine transmembrane transport [GO:1903826]; learning or memory [GO:0007611]; lysosomal lumen acidification [GO:0007042]; lysosomal lumen pH elevation [GO:0035752]; lysosomal protein catabolic process [GO:1905146]; negative regulation of apoptotic process [GO:0043066]; phagosome-lysosome docking [GO:0090384]; phagosome-lysosome fusion [GO:0090385]; plasma membrane raft organization [GO:0044857]; positive regulation of caveolin-mediated endocytosis [GO:2001288]; positive regulation of Golgi to plasma membrane protein transport [GO:0042998]; positive regulation of pinocytosis [GO:0048549]; receptor-mediated endocytosis [GO:0006898]; regulation of arginine biosynthetic process [GO:1900079]; regulation of autophagosome maturation [GO:1901096]; regulation of cellular response to osmotic stress [GO:0106049]; regulation of cytoskeleton organization [GO:0051493]; regulation of fibroblast migration [GO:0010762]; regulation of modification of synaptic structure [GO:1905244]; regulation of phagosome maturation [GO:1905162]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of protein processing [GO:0070613]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic transmission, GABAergic [GO:0032228]; regulation of synaptic transmission, glutamatergic [GO:0051966]; renal potassium excretion [GO:0036359]; vesicle transport along microtubule [GO:0047496] GO:0000139; GO:0005634; GO:0005737; GO:0005764; GO:0005765; GO:0005769; GO:0005770; GO:0005783; GO:0005789; GO:0005794; GO:0005795; GO:0005802; GO:0005829; GO:0005886; GO:0005901; GO:0006898; GO:0007042; GO:0007611; GO:0008021; GO:0009992; GO:0010762; GO:0016020; GO:0031901; GO:0032228; GO:0035752; GO:0036359; GO:0042987; GO:0042998; GO:0043005; GO:0043066; GO:0044754; GO:0044857; GO:0045121; GO:0046474; GO:0046836; GO:0047496; GO:0048172; GO:0048549; GO:0051493; GO:0051861; GO:0051966; GO:0055037; GO:0061909; GO:0070613; GO:0090160; GO:0090384; GO:0090385; GO:0106049; GO:0120146; GO:1900079; GO:1901096; GO:1903076; GO:1903826; GO:1905146; GO:1905162; GO:1905244; GO:2001288 25894 XR_006395699.1 39 140 13 47 23 NA NA NA NA NA NA 25895 XM_029339014.2 801 196 204 314 555 NA NA NA NA NA NA 25896 XM_029347329.2 50 83 23 47 53 NA NA NA NA NA NA 25897 XM_029325914.2 334 526 345 332 313 Q8IVL5 2.8e-107 Prolyl 3-hydroxylase 2 (EC 1.14.11.7) (Leprecan-like protein 1) (Myxoid liposarcoma-associated protein 4) Homo sapiens (Human) collagen metabolic process [GO:0032963]; negative regulation of cell population proliferation [GO:0008285]; peptidyl-proline hydroxylation [GO:0019511] GO:0005506; GO:0005604; GO:0005654; GO:0005783; GO:0005788; GO:0005794; GO:0005829; GO:0008285; GO:0016529; GO:0019511; GO:0019797; GO:0031418; GO:0032963; GO:0043231 25898 XM_029333861.2 56 42 40 137 48 NA NA NA NA NA NA 25899 XR_006392963.1 41 2 25 5 151 NA NA NA NA NA NA 25900 XM_029350368.2 1340 910 665 958 1293 NA NA NA NA NA NA 25901 XM_029333112.2 63 43 38 43 77 Q5RDC7 1.75e-37 RWD domain-containing protein 3 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of hypoxia-inducible factor-1alpha signaling pathway [GO:1902073]; positive regulation of protein sumoylation [GO:0033235] GO:0005634; GO:0005737; GO:0032088; GO:0033235; GO:1902073 25902 XM_029345013.2 180 58 107 217 82 NA NA NA NA NA NA 25903 XM_029335894.2 71 56 54 25 0 NA NA NA NA NA NA 25904 XM_044307655.1 0 8 0 16 7 NA NA NA NA NA NA 25905 XM_029355483.2 430 320 295 310 404 Q3SZK1 2.39e-118 Angio-associated migratory cell protein Bos taurus (Bovine) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; positive regulation of angiogenesis [GO:0045766]; positive regulation of endothelial cell migration [GO:0010595]; smooth muscle cell migration [GO:0014909] GO:0001525; GO:0005829; GO:0005886; GO:0008201; GO:0009986; GO:0010595; GO:0014909; GO:0015630; GO:0030154; GO:0045171; GO:0045766 25906 XM_044307034.1 29 12 9 25 85 B3EWY9 0 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 25907 XM_044307034.1 29 12 9 25 85 B3EWY9 2.39e-32 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 25908 XM_029341801.2 0 29 8 15 7 NA NA NA NA NA NA 25909 XM_029342129.2 2167 940 821 1069 1176 NA NA NA NA NA NA 25910 XR_006397540.1 0 1 0 0 6 NA NA NA NA NA NA 25911 XM_044327035.1 0 0 15 0 0 Q6P6B7 2.12e-83 Ankyrin repeat domain-containing protein 16 Homo sapiens (Human) tRNA modification [GO:0006400] GO:0005634; GO:0005737; GO:0006400 25912 XM_029330345.2 234 0 0 523 209 Q924A2 1.7e-40 Protein capicua homolog Mus musculus (Mouse) brain development [GO:0007420]; learning [GO:0007612]; lung alveolus development [GO:0048286]; memory [GO:0007613]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357]; social behavior [GO:0035176]; transcription by RNA polymerase II [GO:0006366] GO:0000122; GO:0000977; GO:0000981; GO:0003682; GO:0005634; GO:0005654; GO:0006357; GO:0006366; GO:0007420; GO:0007612; GO:0007613; GO:0032991; GO:0035176; GO:0043231; GO:0045892; GO:0048286 25913 XM_029330345.2 234 0 0 523 209 Q924A2 2.13e-21 Protein capicua homolog Mus musculus (Mouse) brain development [GO:0007420]; learning [GO:0007612]; lung alveolus development [GO:0048286]; memory [GO:0007613]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357]; social behavior [GO:0035176]; transcription by RNA polymerase II [GO:0006366] GO:0000122; GO:0000977; GO:0000981; GO:0003682; GO:0005634; GO:0005654; GO:0006357; GO:0006366; GO:0007420; GO:0007612; GO:0007613; GO:0032991; GO:0035176; GO:0043231; GO:0045892; GO:0048286 25914 XM_029337962.2 0 10 0 17 19 NA NA NA NA NA NA 25915 XM_044311627.1 1 3 2 5 20 Q96MB7 4.55e-61 Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease) Homo sapiens (Human) NA GO:0004518; GO:0005634; GO:0005829; GO:0005886; GO:0034451; GO:0046872 25916 XM_044319268.1 2 0 17 16 66 NA NA NA NA NA NA 25917 XM_029330713.2 1733 1880 1139 2182 1700 P00172 1.26e-34 Cytochrome b5 Sus scrofa (Pig) NA GO:0005789; GO:0016020; GO:0020037; GO:0043231; GO:0046872 25918 XR_006397688.1 94 34 0 808 218 NA NA NA NA NA NA 25919 XM_029334820.2 125 50 67 284 290 Q6ZSS7 2.8e-28 Major facilitator superfamily domain-containing protein 6 (Macrophage MHC class I receptor 2 homolog) Homo sapiens (Human) antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590] GO:0005886; GO:0016020; GO:0042590 25920 XM_029344626.2 639 6 164 0 65 NA NA NA NA NA NA 25921 XM_044316292.1 18 0 9 25 4 NA NA NA NA NA NA 25922 XM_044317725.1 449 127 132 222 276 Q64487 5.88e-30 Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48) Mus musculus (Mouse) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; neuron differentiation [GO:0030182]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse assembly [GO:0051965]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; regulation of immune response [GO:0050776]; regulation of postsynaptic density assembly [GO:0099151]; synaptic membrane adhesion [GO:0099560]; trans-synaptic signaling [GO:0099537]; trans-synaptic signaling by trans-synaptic complex [GO:0099545] GO:0004725; GO:0005102; GO:0006470; GO:0007157; GO:0030182; GO:0042734; GO:0046426; GO:0050775; GO:0050776; GO:0050804; GO:0050839; GO:0051965; GO:0097105; GO:0098685; GO:0098686; GO:0098978; GO:0099054; GO:0099151; GO:0099537; GO:0099545; GO:0099560 25923 XM_044317332.1 528 1675 315 1935 1065 NA NA NA NA NA NA 25924 XM_029352664.2 0 0 0 0 31 NA NA NA NA NA NA 25925 XM_044313145.1 376 246 170 255 358 O70546 0 Lysine-specific demethylase 6A (EC 1.14.11.68) (Histone demethylase UTX) (Ubiquitously transcribed TPR protein on the X chromosome) (Ubiquitously transcribed X chromosome tetratricopeptide repeat protein) ([histone H3]-trimethyl-L-lysine(27) demethylase 6A) Mus musculus (Mouse) cellular response to vitamin D [GO:0071305]; chromatin remodeling [GO:0006338]; circulatory system development [GO:0072359]; embryonic organ development [GO:0048568]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; histone H3-K27 demethylation [GO:0071557]; in utero embryonic development [GO:0001701]; mesodermal cell differentiation [GO:0048333]; multicellular organism growth [GO:0035264]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; notochord morphogenesis [GO:0048570]; positive regulation of cell size [GO:0045793]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression [GO:0010468]; respiratory system process [GO:0003016]; somite rostral/caudal axis specification [GO:0032525] GO:0000978; GO:0001701; GO:0001843; GO:0003007; GO:0003016; GO:0005634; GO:0005654; GO:0006338; GO:0007507; GO:0010468; GO:0010628; GO:0021915; GO:0031490; GO:0032525; GO:0035097; GO:0035264; GO:0042802; GO:0044666; GO:0045793; GO:0045944; GO:0046872; GO:0048333; GO:0048568; GO:0048570; GO:0071305; GO:0071557; GO:0071558; GO:0072359; GO:1903298; GO:1990841 25926 XM_044313145.1 376 246 170 255 358 O70546 2.67e-134 Lysine-specific demethylase 6A (EC 1.14.11.68) (Histone demethylase UTX) (Ubiquitously transcribed TPR protein on the X chromosome) (Ubiquitously transcribed X chromosome tetratricopeptide repeat protein) ([histone H3]-trimethyl-L-lysine(27) demethylase 6A) Mus musculus (Mouse) cellular response to vitamin D [GO:0071305]; chromatin remodeling [GO:0006338]; circulatory system development [GO:0072359]; embryonic organ development [GO:0048568]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; histone H3-K27 demethylation [GO:0071557]; in utero embryonic development [GO:0001701]; mesodermal cell differentiation [GO:0048333]; multicellular organism growth [GO:0035264]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; notochord morphogenesis [GO:0048570]; positive regulation of cell size [GO:0045793]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression [GO:0010468]; respiratory system process [GO:0003016]; somite rostral/caudal axis specification [GO:0032525] GO:0000978; GO:0001701; GO:0001843; GO:0003007; GO:0003016; GO:0005634; GO:0005654; GO:0006338; GO:0007507; GO:0010468; GO:0010628; GO:0021915; GO:0031490; GO:0032525; GO:0035097; GO:0035264; GO:0042802; GO:0044666; GO:0045793; GO:0045944; GO:0046872; GO:0048333; GO:0048568; GO:0048570; GO:0071305; GO:0071557; GO:0071558; GO:0072359; GO:1903298; GO:1990841 25927 XM_044316614.1 691 450 524 905 803 Q92797 0 Symplekin Homo sapiens (Human) cell adhesion [GO:0007155]; mRNA polyadenylation [GO:0006378]; negative regulation of protein binding [GO:0032091]; positive regulation of protein dephosphorylation [GO:0035307] GO:0005654; GO:0005737; GO:0005829; GO:0005847; GO:0005856; GO:0005886; GO:0005923; GO:0006378; GO:0007155; GO:0016604; GO:0032091; GO:0035307; GO:0097165 25928 XM_044316246.1 161 128 31 269 51 Q6P1C6 3.85e-117 Leucine-rich repeats and immunoglobulin-like domains protein 3 (LIG-3) Mus musculus (Mouse) otolith morphogenesis [GO:0032474] GO:0005886; GO:0030659; GO:0032474 25929 XM_029356145.2 90 0 0 8 5 NA NA NA NA NA NA 25930 XM_029345781.2 0 0 0 13 0 B8VIW9 4.14e-112 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 25931 XM_044325477.1 24 26 0 7 0 Q80SY4 1.75e-49 E3 ubiquitin-protein ligase MIB1 (EC 2.3.2.27) (DAPK-interacting protein 1) (DIP-1) (Mind bomb homolog 1) (RING-type E3 ubiquitin transferase MIB1) Mus musculus (Mouse) blood vessel development [GO:0001568]; endocytosis [GO:0006897]; heart development [GO:0007507]; heart looping [GO:0001947]; in utero embryonic development [GO:0001701]; negative regulation of neuron differentiation [GO:0045665]; neural tube formation [GO:0001841]; neuron differentiation [GO:0030182]; Notch signaling pathway [GO:0007219]; positive regulation of endocytosis [GO:0045807]; protein ubiquitination [GO:0016567]; somitogenesis [GO:0001756]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0001568; GO:0001701; GO:0001756; GO:0001841; GO:0001947; GO:0004842; GO:0005737; GO:0005813; GO:0005886; GO:0006511; GO:0006897; GO:0007219; GO:0007507; GO:0008270; GO:0014069; GO:0016567; GO:0030182; GO:0031410; GO:0045665; GO:0045807 25932 XM_029356744.2 567 466 466 482 564 Q9Y4P3 4.56e-123 Transducin beta-like protein 2 (WS beta-transducin repeats protein) (WS-betaTRP) (Williams-Beuren syndrome chromosomal region 13 protein) Homo sapiens (Human) cellular response to glucose starvation [GO:0042149]; cellular response to hypoxia [GO:0071456]; endoplasmic reticulum unfolded protein response [GO:0030968] GO:0003723; GO:0005783; GO:0005789; GO:0019901; GO:0030968; GO:0031369; GO:0042149; GO:0051219; GO:0071456 25933 XM_029357842.2 516 65 89 132 62 Q8N0W3 0 L-fucose kinase (Fucokinase) (EC 2.7.1.52) Homo sapiens (Human) carbohydrate phosphorylation [GO:0046835]; GDP-L-fucose salvage [GO:0042352]; response to dopamine [GO:1903350] GO:0005524; GO:0005829; GO:0042352; GO:0046835; GO:0050201; GO:1903350 25934 XM_044319445.1 52 28 18 82 42 Q7TNH6 3.65e-47 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 25935 XM_044319445.1 52 28 18 82 42 Q7TNH6 2.42e-44 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 25936 XM_044319445.1 52 28 18 82 42 Q7TNH6 6.86e-39 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 25937 XM_029323610.2 17 0 17 94 154 Q8WZA2 0 Rap guanine nucleotide exchange factor 4 (Exchange factor directly activated by cAMP 2) (Exchange protein directly activated by cAMP 2) (EPAC 2) (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) Homo sapiens (Human) adaptive immune response [GO:0002250]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; calcium-ion regulated exocytosis [GO:0017156]; G protein-coupled receptor signaling pathway [GO:0007186]; insulin secretion [GO:0030073]; positive regulation of GTPase activity [GO:0043547]; positive regulation of insulin secretion [GO:0032024]; Ras protein signal transduction [GO:0007265]; regulation of exocytosis [GO:0017157]; regulation of synaptic vesicle cycle [GO:0098693] GO:0002250; GO:0005085; GO:0005096; GO:0005829; GO:0005886; GO:0007186; GO:0007189; GO:0007265; GO:0016020; GO:0017156; GO:0017157; GO:0030073; GO:0030552; GO:0030674; GO:0031267; GO:0032024; GO:0043547; GO:0098686; GO:0098693 25938 XM_044317595.1 12 0 21 4 85 Q90YK5 1.62e-38 Heparanase (EC 3.2.1.166) Gallus gallus (Chicken) angiogenesis involved in wound healing [GO:0060055]; cell-matrix adhesion [GO:0007160]; heparan sulfate proteoglycan catabolic process [GO:0030200] GO:0005615; GO:0007160; GO:0016020; GO:0030200; GO:0030305; GO:0031012; GO:0060055 25939 XM_029339792.2 456 297 256 270 331 NA NA NA NA NA NA 25940 XR_006395232.1 4 6 0 5 9 NA NA NA NA NA NA 25941 XR_006393810.1 92 199 164 437 307 NA NA NA NA NA NA 25942 XM_044308854.1 18 0 2 38 0 Q9VBW3 8.1e-73 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 25943 XR_006394427.1 51 26 9 21 18 NA NA NA NA NA NA 25944 XM_029357544.2 3160 2419 2096 3363 2556 Q3T0K1 9.9e-67 Calumenin Bos taurus (Bovine) NA GO:0005509; GO:0005576; GO:0005789; GO:0005794; GO:0033018; GO:0042470 25945 XM_029341929.2 17 0 0 36 33 P97677 7.16e-84 Delta-like protein 1 (Drosophila Delta homolog 1) (Delta1) Rattus norvegicus (Rat) astrocyte development [GO:0014002]; auditory receptor cell fate commitment [GO:0009912]; cell fate determination [GO:0001709]; cell-cell signaling [GO:0007267]; cerebellar molecular layer formation [GO:0021688]; cerebellar Purkinje cell layer structural organization [GO:0021693]; clathrin-dependent endocytosis [GO:0072583]; compartment pattern specification [GO:0007386]; determination of left/right symmetry [GO:0007368]; endothelial tip cell fate specification [GO:0097102]; energy homeostasis [GO:0097009]; heart looping [GO:0001947]; inhibition of neuroepithelial cell differentiation [GO:0002085]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear development [GO:0048839]; lateral inhibition [GO:0046331]; left/right axis specification [GO:0070986]; loop of Henle development [GO:0072070]; marginal zone B cell differentiation [GO:0002315]; myeloid cell differentiation [GO:0030099]; negative regulation of cardiac muscle cell differentiation [GO:2000726]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal cell differentiation [GO:0045605]; negative regulation of epithelial cell differentiation [GO:0030857]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of inner ear auditory receptor cell differentiation [GO:0045608]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of Notch signaling pathway [GO:0045746]; nephron development [GO:0072006]; nervous system development [GO:0007399]; neuroepithelial cell differentiation [GO:0060563]; neuron differentiation [GO:0030182]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; Notch signaling pathway involved in arterial endothelial cell fate commitment [GO:0060853]; organ growth [GO:0035265]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endocytosis [GO:0045807]; positive regulation of gene expression [GO:0010628]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of skeletal muscle tissue growth [GO:0048633]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proximal tubule development [GO:0072014]; proximal/distal pattern formation [GO:0009954]; regulation of blood pressure [GO:0008217]; regulation of cell adhesion [GO:0030155]; regulation of cell division [GO:0051302]; regulation of growth [GO:0040008]; regulation of neurogenesis [GO:0050767]; regulation of skeletal muscle tissue growth [GO:0048631]; regulation of somitogenesis [GO:0014807]; regulation of vascular endothelial growth factor signaling pathway [GO:1900746]; retina development in camera-type eye [GO:0060041]; retina morphogenesis in camera-type eye [GO:0060042]; skeletal muscle tissue growth [GO:0048630]; skin epidermis development [GO:0098773]; somite specification [GO:0001757]; somitogenesis [GO:0001756]; spinal cord development [GO:0021510]; type B pancreatic cell development [GO:0003323] GO:0001709; GO:0001756; GO:0001757; GO:0001947; GO:0002085; GO:0002315; GO:0003323; GO:0005112; GO:0005509; GO:0005886; GO:0005912; GO:0007219; GO:0007267; GO:0007368; GO:0007386; GO:0007399; GO:0008217; GO:0008284; GO:0008285; GO:0009912; GO:0009954; GO:0010628; GO:0014002; GO:0014807; GO:0016324; GO:0021510; GO:0021688; GO:0021693; GO:0030099; GO:0030155; GO:0030182; GO:0030857; GO:0030957; GO:0031410; GO:0032693; GO:0034351; GO:0035265; GO:0040008; GO:0042491; GO:0045121; GO:0045596; GO:0045605; GO:0045608; GO:0045638; GO:0045662; GO:0045665; GO:0045746; GO:0045747; GO:0045807; GO:0045944; GO:0046331; GO:0048018; GO:0048630; GO:0048631; GO:0048633; GO:0048665; GO:0048839; GO:0050767; GO:0051302; GO:0060041; GO:0060042; GO:0060563; GO:0060853; GO:0070986; GO:0072006; GO:0072014; GO:0072070; GO:0072583; GO:0097009; GO:0097102; GO:0097110; GO:0097150; GO:0098773; GO:1900746; GO:1903672; GO:2000726 25946 XR_006395421.1 0 0 23 0 178 NA NA NA NA NA NA 25947 XM_044310485.1 42 135 33 291 60 NA NA NA NA NA NA 25948 XM_029339953.2 0 38 0 0 18 NA NA NA NA NA NA 25949 XM_044316815.1 0 15 6 6 93 NA NA NA NA NA NA 25950 XM_029339619.2 400 464 365 346 326 NA NA NA NA NA NA 25951 XM_029346167.2 5178 8340 6231 13462 8161 NA NA NA NA NA NA 25952 XM_044316227.1 5 0 0 0 14 Q9VBW3 1.55e-54 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 25953 XM_029347866.2 106 242 110 51 75 NA NA NA NA NA NA 25954 XR_006392654.1 98 2 108 23 387 NA NA NA NA NA NA 25955 XM_044323600.1 197 11 75 150 128 B8JK39 1.48e-106 Integrin alpha-9 Mus musculus (Mouse) cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; neutrophil chemotaxis [GO:0030593]; wound healing [GO:0042060] GO:0005178; GO:0005518; GO:0007155; GO:0007160; GO:0007229; GO:0008305; GO:0009897; GO:0009925; GO:0016020; GO:0030593; GO:0033627; GO:0034679; GO:0042060; GO:0043236; GO:0046872; GO:0050900; GO:0098609 25956 XM_044313736.1 52 0 22 10 47 NA NA NA NA NA NA 25957 XM_044306859.1 5 6 21 17 0 B0BM95 4.72e-32 Actin maturation protease (EC 3.4.11.-) (Actin aminopeptidase ACTMAP) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) protein initiator methionine removal involved in protein maturation [GO:0035551] GO:0004177; GO:0035551 25958 XM_029334231.2 74 24 31 22 34 NA NA NA NA NA NA 25959 XM_029337320.2 18999 22516 10364 15929 15384 A7RKS5 2.51e-138 40S ribosomal protein SA Nematostella vectensis (Starlet sea anemone) cytoplasmic translation [GO:0002181]; ribosomal small subunit assembly [GO:0000028]; translation [GO:0006412] GO:0000028; GO:0002181; GO:0003735; GO:0006412; GO:0022627 25960 XM_044319114.1 0 0 84 0 112 NA NA NA NA NA NA 25961 XM_029356661.2 51 74 12 60 18 NA NA NA NA NA NA 25962 XM_044311849.1 22 0 16 4 11 NA NA NA NA NA NA 25963 XM_029344944.2 363 795 529 477 430 NA NA NA NA NA NA 25964 XM_044312222.1 2 44 9 80 40 NA NA NA NA NA NA 25965 XM_029336369.2 338 371 303 970 639 Q0P5X1 2.4e-56 Leucine-rich repeat and IQ domain-containing protein 1 Mus musculus (Mouse) NA GO:0005737; GO:0019901 25966 XM_044321731.1 1331 418 467 780 872 A7SBN6 1e-138 Zinc finger CCCH-type with G patch domain-containing protein Nematostella vectensis (Starlet sea anemone) negative regulation of DNA-templated transcription [GO:0045892]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0045892; GO:0046872 25967 XM_029339664.2 21 0 0 13 0 NA NA NA NA NA NA 25968 XM_044311687.1 58 1 41 13 216 P98133 6.97e-74 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 25969 XM_044311687.1 58 1 41 13 216 P98133 8.62e-74 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 25970 XM_044311687.1 58 1 41 13 216 P98133 2.86e-57 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 25971 XM_044311687.1 58 1 41 13 216 P98133 2.18e-56 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 25972 XM_044311687.1 58 1 41 13 216 P98133 3.49e-54 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 25973 XM_044311687.1 58 1 41 13 216 P98133 3.85e-53 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 25974 XM_044311687.1 58 1 41 13 216 P98133 2.85e-52 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 25975 XM_044311687.1 58 1 41 13 216 P98133 9e-50 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 25976 XM_044311687.1 58 1 41 13 216 P98133 2.9e-47 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 25977 XM_044311687.1 58 1 41 13 216 P98133 2.91e-45 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 25978 XM_044311687.1 58 1 41 13 216 P98133 2.43e-44 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 25979 XM_044311687.1 58 1 41 13 216 P98133 1.97e-42 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 25980 XM_044311687.1 58 1 41 13 216 P98133 9.56e-42 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 25981 XM_044311687.1 58 1 41 13 216 P98133 2.29e-39 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 25982 XM_044311687.1 58 1 41 13 216 P98133 4.05e-38 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 25983 XM_044311687.1 58 1 41 13 216 P98133 1.99e-37 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 25984 XM_044311687.1 58 1 41 13 216 P98133 1.42e-33 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 25985 XM_044311687.1 58 1 41 13 216 P98133 8.21e-24 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 25986 XM_029326530.2 184 63 51 130 214 NA NA NA NA NA NA 25987 XR_006392006.1 430 223 152 120 1291 Q91VS8 2.12e-136 FERM, ARHGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR) (FERM, RhoGEF and pleckstrin domain-containing protein 2) Mus musculus (Mouse) actin cytoskeleton reorganization [GO:0031532]; cell adhesion [GO:0007155]; hair cycle process [GO:0022405]; neuron remodeling [GO:0016322]; osteoclast differentiation [GO:0030316]; podosome assembly [GO:0071800]; Rac protein signal transduction [GO:0016601]; regulation of integrin activation [GO:0033623]; semaphorin-plexin signaling pathway [GO:0071526] GO:0005085; GO:0005737; GO:0005829; GO:0005856; GO:0007155; GO:0008092; GO:0016322; GO:0016601; GO:0022405; GO:0030316; GO:0031532; GO:0033623; GO:0071526; GO:0071800 25988 XR_006392006.1 430 223 152 120 1291 Q91VS8 1.43e-38 FERM, ARHGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR) (FERM, RhoGEF and pleckstrin domain-containing protein 2) Mus musculus (Mouse) actin cytoskeleton reorganization [GO:0031532]; cell adhesion [GO:0007155]; hair cycle process [GO:0022405]; neuron remodeling [GO:0016322]; osteoclast differentiation [GO:0030316]; podosome assembly [GO:0071800]; Rac protein signal transduction [GO:0016601]; regulation of integrin activation [GO:0033623]; semaphorin-plexin signaling pathway [GO:0071526] GO:0005085; GO:0005737; GO:0005829; GO:0005856; GO:0007155; GO:0008092; GO:0016322; GO:0016601; GO:0022405; GO:0030316; GO:0031532; GO:0033623; GO:0071526; GO:0071800 25989 XM_029340584.2 1 8 4 28 15 NA NA NA NA NA NA 25990 XM_029356849.2 572 631 491 862 932 NA NA NA NA NA NA 25991 XM_044309379.1 0 3 0 11 7 NA NA NA NA NA NA 25992 XM_029338501.2 42 0 0 10 4 Q95JY5 4.04e-25 Sterile alpha motif domain-containing protein 15 (SAM domain-containing protein 15) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA NA 25993 XM_029357970.2 37 24 16 43 52 Q9VQ56 2.03e-62 Fez family zinc finger protein erm (Earmuff) Drosophila melanogaster (Fruit fly) axon target recognition [GO:0007412]; axonogenesis involved in innervation [GO:0060385]; cell dedifferentiation [GO:0043697]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; negative regulation of neuroblast proliferation [GO:0007406]; photoreceptor cell axon guidance [GO:0072499]; positive regulation of gene expression [GO:0010628]; positive regulation of netrin-activated signaling pathway [GO:1902843]; positive regulation of neuron differentiation [GO:0045666]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of transcription by RNA polymerase II [GO:0006357]; stem cell population maintenance [GO:0019827] GO:0000976; GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0007406; GO:0007412; GO:0010628; GO:0010629; GO:0019827; GO:0043025; GO:0043565; GO:0043697; GO:0044295; GO:0045666; GO:0045892; GO:0046872; GO:0050767; GO:0060385; GO:0072499; GO:1902692; GO:1902843 25994 XM_044320511.1 43 41 18 177 265 C0H691 2.1e-34 Small cysteine-rich protein 2 (Amil-SCRiP2) (SCRiP2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0042151; GO:0090729 25995 XM_029355080.2 0 65 60 0 0 NA NA NA NA NA NA 25996 XM_044315718.1 4 4 9 4 12 Q9VCA2 1.79e-84 Organic cation transporter protein Drosophila melanogaster (Fruit fly) apoptotic process [GO:0006915]; ion transport [GO:0006811] GO:0006811; GO:0006915; GO:0016020; GO:0022857 25997 XR_006396611.1 0 17 9 9 2 NA NA NA NA NA NA 25998 XM_029351220.2 63 71 38 65 30 NA NA NA NA NA NA 25999 XM_029352561.2 2317 2980 2194 1684 1564 NA NA NA NA NA NA 26000 XR_006395697.1 0 4 28 26 33 NA NA NA NA NA NA 26001 XR_006392946.1 41 2 25 5 151 NA NA NA NA NA NA 26002 XR_003825195.2 0 0 10 0 25 NA NA NA NA NA NA 26003 XM_044308038.1 0 0 0 37 0 NA NA NA NA NA NA 26004 XM_029347658.2 65 12 93 115 0 Q0EEE2 4.96e-68 Patched domain-containing protein 3 (RND-type protein RNDEu-3) Mus musculus (Mouse) NA GO:0005783; GO:0005789; GO:0005886; GO:0016020; GO:0097225 26005 XR_006397307.1 13 0 28 25 37 NA NA NA NA NA NA 26006 XM_029334363.2 42 6 21 33 257 NA NA NA NA NA NA 26007 XM_044322875.1 500 277 337 290 442 D4AD75 0 NA NA NA NA 26008 XM_044311148.1 42 0 9 5 7 NA NA NA NA NA NA 26009 XM_029351008.2 5 0 0 6 0 NA NA NA NA NA NA 26010 XM_029334427.2 264 288 304 278 796 Q01705 2.5e-111 Neurogenic locus notch homolog protein 1 (Notch 1) (Motch A) (mT14) (p300) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)] Mus musculus (Mouse) animal organ regeneration [GO:0031100]; aortic valve morphogenesis [GO:0003180]; apoptotic process [GO:0006915]; apoptotic process involved in embryonic digit morphogenesis [GO:1902263]; arterial endothelial cell differentiation [GO:0060842]; astrocyte differentiation [GO:0048708]; atrioventricular node development [GO:0003162]; atrioventricular valve morphogenesis [GO:0003181]; auditory receptor cell fate commitment [GO:0009912]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; branching morphogenesis of an epithelial tube [GO:0048754]; calcium-ion regulated exocytosis [GO:0017156]; cardiac atrium morphogenesis [GO:0003209]; cardiac chamber formation [GO:0003207]; cardiac epithelial to mesenchymal transition [GO:0060317]; cardiac left ventricle morphogenesis [GO:0003214]; cardiac muscle cell myoblast differentiation [GO:0060379]; cardiac muscle cell proliferation [GO:0060038]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac right atrium morphogenesis [GO:0003213]; cardiac right ventricle formation [GO:0003219]; cardiac septum morphogenesis [GO:0060411]; cardiac vascular smooth muscle cell development [GO:0060948]; cardiac ventricle morphogenesis [GO:0003208]; cell differentiation [GO:0030154]; cell differentiation in spinal cord [GO:0021515]; cell migration involved in endocardial cushion formation [GO:0003273]; cell population proliferation [GO:0008283]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to hypoxia [GO:0071456]; cellular response to tumor cell [GO:0071228]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cilium assembly [GO:0060271]; collecting duct development [GO:0072044]; compartment pattern specification [GO:0007386]; coronary artery morphogenesis [GO:0060982]; coronary sinus valve morphogenesis [GO:0003182]; coronary vein morphogenesis [GO:0003169]; determination of left/right symmetry [GO:0007368]; distal tubule development [GO:0072017]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; endocardial cell differentiation [GO:0060956]; endocardial cushion development [GO:0003197]; endocardial cushion morphogenesis [GO:0003203]; endocardium development [GO:0003157]; endocardium morphogenesis [GO:0003160]; endoderm development [GO:0007492]; epidermal cell fate specification [GO:0009957]; epidermis development [GO:0008544]; epithelial cell fate commitment [GO:0072148]; epithelial cell proliferation [GO:0050673]; epithelial to mesenchymal transition [GO:0001837]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; forebrain development [GO:0030900]; foregut morphogenesis [GO:0007440]; gene expression [GO:0010467]; glial cell differentiation [GO:0010001]; glomerular mesangial cell development [GO:0072144]; growth involved in heart morphogenesis [GO:0003241]; hair follicle morphogenesis [GO:0031069]; heart development [GO:0007507]; heart looping [GO:0001947]; heart trabecula morphogenesis [GO:0061384]; homeostasis of number of cells within a tissue [GO:0048873]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; inhibition of neuroepithelial cell differentiation [GO:0002085]; interleukin-17-mediated signaling pathway [GO:0097400]; keratinocyte differentiation [GO:0030216]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; lung development [GO:0030324]; mesenchymal cell development [GO:0014031]; mitral valve formation [GO:0003192]; negative regulation of anoikis [GO:2000811]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of catalytic activity [GO:0043086]; negative regulation of cell adhesion molecule production [GO:0060354]; negative regulation of cell death [GO:0060548]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell proliferation involved in heart valve morphogenesis [GO:0003252]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of endothelial cell chemotaxis [GO:2001027]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of extracellular matrix constituent secretion [GO:0003332]; negative regulation of gene expression [GO:0010629]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of inner ear auditory receptor cell differentiation [GO:0045608]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of ossification [GO:0030279]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of photoreceptor cell differentiation [GO:0046533]; negative regulation of pro-B cell differentiation [GO:2000974]; negative regulation of stem cell differentiation [GO:2000737]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube development [GO:0021915]; neuroendocrine cell differentiation [GO:0061101]; neuron differentiation [GO:0030182]; neuron fate commitment [GO:0048663]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation [GO:0003270]; oligodendrocyte differentiation [GO:0048709]; osteoblast fate commitment [GO:0002051]; outflow tract morphogenesis [GO:0003151]; pericardium morphogenesis [GO:0003344]; positive regulation of aorta morphogenesis [GO:1903849]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic process involved in morphogenesis [GO:1902339]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac epithelial to mesenchymal transition [GO:0062043]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of ephrin receptor signaling pathway [GO:1901189]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell differentiation [GO:0045687]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of viral genome replication [GO:0045070]; positive regulation of viral transcription [GO:0050434]; prostate gland epithelium morphogenesis [GO:0060740]; protein catabolic process [GO:0030163]; protein import into nucleus [GO:0006606]; pulmonary valve morphogenesis [GO:0003184]; regulation of cardioblast proliferation [GO:0003264]; regulation of cell adhesion involved in heart morphogenesis [GO:0061344]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127]; regulation of epithelial cell proliferation [GO:0050678]; regulation of epithelial cell proliferation involved in prostate gland development [GO:0060768]; regulation of extracellular matrix assembly [GO:1901201]; regulation of gene expression [GO:0010468]; regulation of inner ear auditory receptor cell differentiation [GO:0045607]; regulation of neurogenesis [GO:0050767]; regulation of Notch signaling pathway [GO:0008593]; regulation of somitogenesis [GO:0014807]; regulation of stem cell proliferation [GO:0072091]; regulation of transcription by RNA polymerase II [GO:0006357]; response to corticosteroid [GO:0031960]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; retinal cone cell differentiation [GO:0042670]; secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development [GO:0060528]; skeletal muscle cell differentiation [GO:0035914]; somatic stem cell division [GO:0048103]; spermatogenesis [GO:0007283]; sprouting angiogenesis [GO:0002040]; T-helper 17 type immune response [GO:0072538]; tissue regeneration [GO:0042246]; transcription by RNA polymerase II [GO:0006366]; tube formation [GO:0035148]; vasculogenesis involved in coronary vascular morphogenesis [GO:0060979]; venous blood vessel morphogenesis [GO:0048845]; venous endothelial cell differentiation [GO:0060843]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222] GO:0000122; GO:0000139; GO:0001669; GO:0001701; GO:0001726; GO:0001837; GO:0001889; GO:0001947; GO:0002040; GO:0002051; GO:0002052; GO:0002085; GO:0002193; GO:0002437; GO:0003151; GO:0003157; GO:0003160; GO:0003162; GO:0003169; GO:0003180; GO:0003181; GO:0003182; GO:0003184; GO:0003192; GO:0003197; GO:0003198; GO:0003203; GO:0003207; GO:0003208; GO:0003209; GO:0003213; GO:0003214; GO:0003219; GO:0003222; GO:0003241; GO:0003252; GO:0003264; GO:0003270; GO:0003273; GO:0003332; GO:0003344; GO:0003682; GO:0003713; GO:0004857; GO:0004888; GO:0005112; GO:0005509; GO:0005576; GO:0005634; GO:0005654; GO:0005737; GO:0005783; GO:0005789; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0005912; GO:0006357; GO:0006366; GO:0006606; GO:0006915; GO:0006959; GO:0007219; GO:0007221; GO:0007283; GO:0007368; GO:0007386; GO:0007409; GO:0007411; GO:0007440; GO:0007492; GO:0007507; GO:0008283; GO:0008284; GO:0008285; GO:0008544; GO:0008593; GO:0009912; GO:0009957; GO:0009986; GO:0010001; GO:0010467; GO:0010468; GO:0010614; GO:0010628; GO:0010629; GO:0010718; GO:0010812; GO:0010832; GO:0014031; GO:0014807; GO:0016324; GO:0017156; GO:0019899; GO:0021515; GO:0021915; GO:0030027; GO:0030154; GO:0030163; GO:0030182; GO:0030216; GO:0030279; GO:0030324; GO:0030326; GO:0030334; GO:0030335; GO:0030513; GO:0030514; GO:0030900; GO:0031069; GO:0031100; GO:0031410; GO:0031490; GO:0031960; GO:0032495; GO:0032496; GO:0032966; GO:0035116; GO:0035148; GO:0035914; GO:0035924; GO:0042127; GO:0042246; GO:0042670; GO:0042802; GO:0043065; GO:0043086; GO:0043235; GO:0045070; GO:0045603; GO:0045607; GO:0045608; GO:0045618; GO:0045662; GO:0045665; GO:0045668; GO:0045687; GO:0045747; GO:0045892; GO:0045893; GO:0045944; GO:0045955; GO:0046427; GO:0046533; GO:0046579; GO:0048103; GO:0048663; GO:0048708; GO:0048709; GO:0048711; GO:0048715; GO:0048754; GO:0048845; GO:0048873; GO:0050434; GO:0050673; GO:0050678; GO:0050679; GO:0050680; GO:0050767; GO:0050768; GO:0055008; GO:0060038; GO:0060045; GO:0060253; GO:0060271; GO:0060317; GO:0060354; GO:0060379; GO:0060411; GO:0060412; GO:0060528; GO:0060548; GO:0060740; GO:0060768; GO:0060842; GO:0060843; GO:0060948; GO:0060956; GO:0060979; GO:0060982; GO:0061101; GO:0061314; GO:0061344; GO:0061384; GO:0062043; GO:0070168; GO:0070374; GO:0070986; GO:0071228; GO:0071372; GO:0071456; GO:0071944; GO:0072017; GO:0072044; GO:0072091; GO:0072144; GO:0072148; GO:0072538; GO:0090051; GO:0090090; GO:0097150; GO:0097400; GO:0120163; GO:0140537; GO:1901189; GO:1901201; GO:1902263; GO:1902339; GO:1903849; GO:2000048; GO:2000737; GO:2000811; GO:2000974; GO:2001027 26011 XM_029334427.2 264 288 304 278 796 Q01705 3.27e-103 Neurogenic locus notch homolog protein 1 (Notch 1) (Motch A) (mT14) (p300) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)] Mus musculus (Mouse) animal organ regeneration [GO:0031100]; aortic valve morphogenesis [GO:0003180]; apoptotic process [GO:0006915]; apoptotic process involved in embryonic digit morphogenesis [GO:1902263]; arterial endothelial cell differentiation [GO:0060842]; astrocyte differentiation [GO:0048708]; atrioventricular node development [GO:0003162]; atrioventricular valve morphogenesis [GO:0003181]; auditory receptor cell fate commitment [GO:0009912]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; branching morphogenesis of an epithelial tube [GO:0048754]; calcium-ion regulated exocytosis [GO:0017156]; cardiac atrium morphogenesis [GO:0003209]; cardiac chamber formation [GO:0003207]; cardiac epithelial to mesenchymal transition [GO:0060317]; cardiac left ventricle morphogenesis [GO:0003214]; cardiac muscle cell myoblast differentiation [GO:0060379]; cardiac muscle cell proliferation [GO:0060038]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac right atrium morphogenesis [GO:0003213]; cardiac right ventricle formation [GO:0003219]; cardiac septum morphogenesis [GO:0060411]; cardiac vascular smooth muscle cell development [GO:0060948]; cardiac ventricle morphogenesis [GO:0003208]; cell differentiation [GO:0030154]; cell differentiation in spinal cord [GO:0021515]; cell migration involved in endocardial cushion formation [GO:0003273]; cell population proliferation [GO:0008283]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to hypoxia [GO:0071456]; cellular response to tumor cell [GO:0071228]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cilium assembly [GO:0060271]; collecting duct development [GO:0072044]; compartment pattern specification [GO:0007386]; coronary artery morphogenesis [GO:0060982]; coronary sinus valve morphogenesis [GO:0003182]; coronary vein morphogenesis [GO:0003169]; determination of left/right symmetry [GO:0007368]; distal tubule development [GO:0072017]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; endocardial cell differentiation [GO:0060956]; endocardial cushion development [GO:0003197]; endocardial cushion morphogenesis [GO:0003203]; endocardium development [GO:0003157]; endocardium morphogenesis [GO:0003160]; endoderm development [GO:0007492]; epidermal cell fate specification [GO:0009957]; epidermis development [GO:0008544]; epithelial cell fate commitment [GO:0072148]; epithelial cell proliferation [GO:0050673]; epithelial to mesenchymal transition [GO:0001837]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; forebrain development [GO:0030900]; foregut morphogenesis [GO:0007440]; gene expression [GO:0010467]; glial cell differentiation [GO:0010001]; glomerular mesangial cell development [GO:0072144]; growth involved in heart morphogenesis [GO:0003241]; hair follicle morphogenesis [GO:0031069]; heart development [GO:0007507]; heart looping [GO:0001947]; heart trabecula morphogenesis [GO:0061384]; homeostasis of number of cells within a tissue [GO:0048873]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; inhibition of neuroepithelial cell differentiation [GO:0002085]; interleukin-17-mediated signaling pathway [GO:0097400]; keratinocyte differentiation [GO:0030216]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; lung development [GO:0030324]; mesenchymal cell development [GO:0014031]; mitral valve formation [GO:0003192]; negative regulation of anoikis [GO:2000811]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of catalytic activity [GO:0043086]; negative regulation of cell adhesion molecule production [GO:0060354]; negative regulation of cell death [GO:0060548]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell proliferation involved in heart valve morphogenesis [GO:0003252]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of endothelial cell chemotaxis [GO:2001027]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of extracellular matrix constituent secretion [GO:0003332]; negative regulation of gene expression [GO:0010629]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of inner ear auditory receptor cell differentiation [GO:0045608]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of ossification [GO:0030279]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of photoreceptor cell differentiation [GO:0046533]; negative regulation of pro-B cell differentiation [GO:2000974]; negative regulation of stem cell differentiation [GO:2000737]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube development [GO:0021915]; neuroendocrine cell differentiation [GO:0061101]; neuron differentiation [GO:0030182]; neuron fate commitment [GO:0048663]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation [GO:0003270]; oligodendrocyte differentiation [GO:0048709]; osteoblast fate commitment [GO:0002051]; outflow tract morphogenesis [GO:0003151]; pericardium morphogenesis [GO:0003344]; positive regulation of aorta morphogenesis [GO:1903849]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic process involved in morphogenesis [GO:1902339]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac epithelial to mesenchymal transition [GO:0062043]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of ephrin receptor signaling pathway [GO:1901189]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell differentiation [GO:0045687]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of viral genome replication [GO:0045070]; positive regulation of viral transcription [GO:0050434]; prostate gland epithelium morphogenesis [GO:0060740]; protein catabolic process [GO:0030163]; protein import into nucleus [GO:0006606]; pulmonary valve morphogenesis [GO:0003184]; regulation of cardioblast proliferation [GO:0003264]; regulation of cell adhesion involved in heart morphogenesis [GO:0061344]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127]; regulation of epithelial cell proliferation [GO:0050678]; regulation of epithelial cell proliferation involved in prostate gland development [GO:0060768]; regulation of extracellular matrix assembly [GO:1901201]; regulation of gene expression [GO:0010468]; regulation of inner ear auditory receptor cell differentiation [GO:0045607]; regulation of neurogenesis [GO:0050767]; regulation of Notch signaling pathway [GO:0008593]; regulation of somitogenesis [GO:0014807]; regulation of stem cell proliferation [GO:0072091]; regulation of transcription by RNA polymerase II [GO:0006357]; response to corticosteroid [GO:0031960]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; retinal cone cell differentiation [GO:0042670]; secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development [GO:0060528]; skeletal muscle cell differentiation [GO:0035914]; somatic stem cell division [GO:0048103]; spermatogenesis [GO:0007283]; sprouting angiogenesis [GO:0002040]; T-helper 17 type immune response [GO:0072538]; tissue regeneration [GO:0042246]; transcription by RNA polymerase II [GO:0006366]; tube formation [GO:0035148]; vasculogenesis involved in coronary vascular morphogenesis [GO:0060979]; venous blood vessel morphogenesis [GO:0048845]; venous endothelial cell differentiation [GO:0060843]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222] GO:0000122; GO:0000139; GO:0001669; GO:0001701; GO:0001726; GO:0001837; GO:0001889; GO:0001947; GO:0002040; GO:0002051; GO:0002052; GO:0002085; GO:0002193; GO:0002437; GO:0003151; GO:0003157; GO:0003160; GO:0003162; GO:0003169; GO:0003180; GO:0003181; GO:0003182; GO:0003184; GO:0003192; GO:0003197; GO:0003198; GO:0003203; GO:0003207; GO:0003208; GO:0003209; GO:0003213; GO:0003214; GO:0003219; GO:0003222; GO:0003241; GO:0003252; GO:0003264; GO:0003270; GO:0003273; GO:0003332; GO:0003344; GO:0003682; GO:0003713; GO:0004857; GO:0004888; GO:0005112; GO:0005509; GO:0005576; GO:0005634; GO:0005654; GO:0005737; GO:0005783; GO:0005789; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0005912; GO:0006357; GO:0006366; GO:0006606; GO:0006915; GO:0006959; GO:0007219; GO:0007221; GO:0007283; GO:0007368; GO:0007386; GO:0007409; GO:0007411; GO:0007440; GO:0007492; GO:0007507; GO:0008283; GO:0008284; GO:0008285; GO:0008544; GO:0008593; GO:0009912; GO:0009957; GO:0009986; GO:0010001; GO:0010467; GO:0010468; GO:0010614; GO:0010628; GO:0010629; GO:0010718; GO:0010812; GO:0010832; GO:0014031; GO:0014807; GO:0016324; GO:0017156; GO:0019899; GO:0021515; GO:0021915; GO:0030027; GO:0030154; GO:0030163; GO:0030182; GO:0030216; GO:0030279; GO:0030324; GO:0030326; GO:0030334; GO:0030335; GO:0030513; GO:0030514; GO:0030900; GO:0031069; GO:0031100; GO:0031410; GO:0031490; GO:0031960; GO:0032495; GO:0032496; GO:0032966; GO:0035116; GO:0035148; GO:0035914; GO:0035924; GO:0042127; GO:0042246; GO:0042670; GO:0042802; GO:0043065; GO:0043086; GO:0043235; GO:0045070; GO:0045603; GO:0045607; GO:0045608; GO:0045618; GO:0045662; GO:0045665; GO:0045668; GO:0045687; GO:0045747; GO:0045892; GO:0045893; GO:0045944; GO:0045955; GO:0046427; GO:0046533; GO:0046579; GO:0048103; GO:0048663; GO:0048708; GO:0048709; GO:0048711; GO:0048715; GO:0048754; GO:0048845; GO:0048873; GO:0050434; GO:0050673; GO:0050678; GO:0050679; GO:0050680; GO:0050767; GO:0050768; GO:0055008; GO:0060038; GO:0060045; GO:0060253; GO:0060271; GO:0060317; GO:0060354; GO:0060379; GO:0060411; GO:0060412; GO:0060528; GO:0060548; GO:0060740; GO:0060768; GO:0060842; GO:0060843; GO:0060948; GO:0060956; GO:0060979; GO:0060982; GO:0061101; GO:0061314; GO:0061344; GO:0061384; GO:0062043; GO:0070168; GO:0070374; GO:0070986; GO:0071228; GO:0071372; GO:0071456; GO:0071944; GO:0072017; GO:0072044; GO:0072091; GO:0072144; GO:0072148; GO:0072538; GO:0090051; GO:0090090; GO:0097150; GO:0097400; GO:0120163; GO:0140537; GO:1901189; GO:1901201; GO:1902263; GO:1902339; GO:1903849; GO:2000048; GO:2000737; GO:2000811; GO:2000974; GO:2001027 26012 XM_029334427.2 264 288 304 278 796 Q01705 7.65e-99 Neurogenic locus notch homolog protein 1 (Notch 1) (Motch A) (mT14) (p300) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)] Mus musculus (Mouse) animal organ regeneration [GO:0031100]; aortic valve morphogenesis [GO:0003180]; apoptotic process [GO:0006915]; apoptotic process involved in embryonic digit morphogenesis [GO:1902263]; arterial endothelial cell differentiation [GO:0060842]; astrocyte differentiation [GO:0048708]; atrioventricular node development [GO:0003162]; atrioventricular valve morphogenesis [GO:0003181]; auditory receptor cell fate commitment [GO:0009912]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; branching morphogenesis of an epithelial tube [GO:0048754]; calcium-ion regulated exocytosis [GO:0017156]; cardiac atrium morphogenesis [GO:0003209]; cardiac chamber formation [GO:0003207]; cardiac epithelial to mesenchymal transition [GO:0060317]; cardiac left ventricle morphogenesis [GO:0003214]; cardiac muscle cell myoblast differentiation [GO:0060379]; cardiac muscle cell proliferation [GO:0060038]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac right atrium morphogenesis [GO:0003213]; cardiac right ventricle formation [GO:0003219]; cardiac septum morphogenesis [GO:0060411]; cardiac vascular smooth muscle cell development [GO:0060948]; cardiac ventricle morphogenesis [GO:0003208]; cell differentiation [GO:0030154]; cell differentiation in spinal cord [GO:0021515]; cell migration involved in endocardial cushion formation [GO:0003273]; cell population proliferation [GO:0008283]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to hypoxia [GO:0071456]; cellular response to tumor cell [GO:0071228]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cilium assembly [GO:0060271]; collecting duct development [GO:0072044]; compartment pattern specification [GO:0007386]; coronary artery morphogenesis [GO:0060982]; coronary sinus valve morphogenesis [GO:0003182]; coronary vein morphogenesis [GO:0003169]; determination of left/right symmetry [GO:0007368]; distal tubule development [GO:0072017]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; endocardial cell differentiation [GO:0060956]; endocardial cushion development [GO:0003197]; endocardial cushion morphogenesis [GO:0003203]; endocardium development [GO:0003157]; endocardium morphogenesis [GO:0003160]; endoderm development [GO:0007492]; epidermal cell fate specification [GO:0009957]; epidermis development [GO:0008544]; epithelial cell fate commitment [GO:0072148]; epithelial cell proliferation [GO:0050673]; epithelial to mesenchymal transition [GO:0001837]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; forebrain development [GO:0030900]; foregut morphogenesis [GO:0007440]; gene expression [GO:0010467]; glial cell differentiation [GO:0010001]; glomerular mesangial cell development [GO:0072144]; growth involved in heart morphogenesis [GO:0003241]; hair follicle morphogenesis [GO:0031069]; heart development [GO:0007507]; heart looping [GO:0001947]; heart trabecula morphogenesis [GO:0061384]; homeostasis of number of cells within a tissue [GO:0048873]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; inhibition of neuroepithelial cell differentiation [GO:0002085]; interleukin-17-mediated signaling pathway [GO:0097400]; keratinocyte differentiation [GO:0030216]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; lung development [GO:0030324]; mesenchymal cell development [GO:0014031]; mitral valve formation [GO:0003192]; negative regulation of anoikis [GO:2000811]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of catalytic activity [GO:0043086]; negative regulation of cell adhesion molecule production [GO:0060354]; negative regulation of cell death [GO:0060548]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell proliferation involved in heart valve morphogenesis [GO:0003252]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of endothelial cell chemotaxis [GO:2001027]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of extracellular matrix constituent secretion [GO:0003332]; negative regulation of gene expression [GO:0010629]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of inner ear auditory receptor cell differentiation [GO:0045608]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of ossification [GO:0030279]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of photoreceptor cell differentiation [GO:0046533]; negative regulation of pro-B cell differentiation [GO:2000974]; negative regulation of stem cell differentiation [GO:2000737]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube development [GO:0021915]; neuroendocrine cell differentiation [GO:0061101]; neuron differentiation [GO:0030182]; neuron fate commitment [GO:0048663]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation [GO:0003270]; oligodendrocyte differentiation [GO:0048709]; osteoblast fate commitment [GO:0002051]; outflow tract morphogenesis [GO:0003151]; pericardium morphogenesis [GO:0003344]; positive regulation of aorta morphogenesis [GO:1903849]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic process involved in morphogenesis [GO:1902339]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac epithelial to mesenchymal transition [GO:0062043]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of ephrin receptor signaling pathway [GO:1901189]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell differentiation [GO:0045687]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of viral genome replication [GO:0045070]; positive regulation of viral transcription [GO:0050434]; prostate gland epithelium morphogenesis [GO:0060740]; protein catabolic process [GO:0030163]; protein import into nucleus [GO:0006606]; pulmonary valve morphogenesis [GO:0003184]; regulation of cardioblast proliferation [GO:0003264]; regulation of cell adhesion involved in heart morphogenesis [GO:0061344]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127]; regulation of epithelial cell proliferation [GO:0050678]; regulation of epithelial cell proliferation involved in prostate gland development [GO:0060768]; regulation of extracellular matrix assembly [GO:1901201]; regulation of gene expression [GO:0010468]; regulation of inner ear auditory receptor cell differentiation [GO:0045607]; regulation of neurogenesis [GO:0050767]; regulation of Notch signaling pathway [GO:0008593]; regulation of somitogenesis [GO:0014807]; regulation of stem cell proliferation [GO:0072091]; regulation of transcription by RNA polymerase II [GO:0006357]; response to corticosteroid [GO:0031960]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; retinal cone cell differentiation [GO:0042670]; secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development [GO:0060528]; skeletal muscle cell differentiation [GO:0035914]; somatic stem cell division [GO:0048103]; spermatogenesis [GO:0007283]; sprouting angiogenesis [GO:0002040]; T-helper 17 type immune response [GO:0072538]; tissue regeneration [GO:0042246]; transcription by RNA polymerase II [GO:0006366]; tube formation [GO:0035148]; vasculogenesis involved in coronary vascular morphogenesis [GO:0060979]; venous blood vessel morphogenesis [GO:0048845]; venous endothelial cell differentiation [GO:0060843]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222] GO:0000122; GO:0000139; GO:0001669; GO:0001701; GO:0001726; GO:0001837; GO:0001889; GO:0001947; GO:0002040; GO:0002051; GO:0002052; GO:0002085; GO:0002193; GO:0002437; GO:0003151; GO:0003157; GO:0003160; GO:0003162; GO:0003169; GO:0003180; GO:0003181; GO:0003182; GO:0003184; GO:0003192; GO:0003197; GO:0003198; GO:0003203; GO:0003207; GO:0003208; GO:0003209; GO:0003213; GO:0003214; GO:0003219; GO:0003222; GO:0003241; GO:0003252; GO:0003264; GO:0003270; GO:0003273; GO:0003332; GO:0003344; GO:0003682; GO:0003713; GO:0004857; GO:0004888; GO:0005112; GO:0005509; GO:0005576; GO:0005634; GO:0005654; GO:0005737; GO:0005783; GO:0005789; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0005912; GO:0006357; GO:0006366; GO:0006606; GO:0006915; GO:0006959; GO:0007219; GO:0007221; GO:0007283; GO:0007368; GO:0007386; GO:0007409; GO:0007411; GO:0007440; GO:0007492; GO:0007507; GO:0008283; GO:0008284; GO:0008285; GO:0008544; GO:0008593; GO:0009912; GO:0009957; GO:0009986; GO:0010001; GO:0010467; GO:0010468; GO:0010614; GO:0010628; GO:0010629; GO:0010718; GO:0010812; GO:0010832; GO:0014031; GO:0014807; GO:0016324; GO:0017156; GO:0019899; GO:0021515; GO:0021915; GO:0030027; GO:0030154; GO:0030163; GO:0030182; GO:0030216; GO:0030279; GO:0030324; GO:0030326; GO:0030334; GO:0030335; GO:0030513; GO:0030514; GO:0030900; GO:0031069; GO:0031100; GO:0031410; GO:0031490; GO:0031960; GO:0032495; GO:0032496; GO:0032966; GO:0035116; GO:0035148; GO:0035914; GO:0035924; GO:0042127; GO:0042246; GO:0042670; GO:0042802; GO:0043065; GO:0043086; GO:0043235; GO:0045070; GO:0045603; GO:0045607; GO:0045608; GO:0045618; GO:0045662; GO:0045665; GO:0045668; GO:0045687; GO:0045747; GO:0045892; GO:0045893; GO:0045944; GO:0045955; GO:0046427; GO:0046533; GO:0046579; GO:0048103; GO:0048663; GO:0048708; GO:0048709; GO:0048711; GO:0048715; GO:0048754; GO:0048845; GO:0048873; GO:0050434; GO:0050673; GO:0050678; GO:0050679; GO:0050680; GO:0050767; GO:0050768; GO:0055008; GO:0060038; GO:0060045; GO:0060253; GO:0060271; GO:0060317; GO:0060354; GO:0060379; GO:0060411; GO:0060412; GO:0060528; GO:0060548; GO:0060740; GO:0060768; GO:0060842; GO:0060843; GO:0060948; GO:0060956; GO:0060979; GO:0060982; GO:0061101; GO:0061314; GO:0061344; GO:0061384; GO:0062043; GO:0070168; GO:0070374; GO:0070986; GO:0071228; GO:0071372; GO:0071456; GO:0071944; GO:0072017; GO:0072044; GO:0072091; GO:0072144; GO:0072148; GO:0072538; GO:0090051; GO:0090090; GO:0097150; GO:0097400; GO:0120163; GO:0140537; GO:1901189; GO:1901201; GO:1902263; GO:1902339; GO:1903849; GO:2000048; GO:2000737; GO:2000811; GO:2000974; GO:2001027 26013 XM_029334427.2 264 288 304 278 796 Q01705 1.78e-93 Neurogenic locus notch homolog protein 1 (Notch 1) (Motch A) (mT14) (p300) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)] Mus musculus (Mouse) animal organ regeneration [GO:0031100]; aortic valve morphogenesis [GO:0003180]; apoptotic process [GO:0006915]; apoptotic process involved in embryonic digit morphogenesis [GO:1902263]; arterial endothelial cell differentiation [GO:0060842]; astrocyte differentiation [GO:0048708]; atrioventricular node development [GO:0003162]; atrioventricular valve morphogenesis [GO:0003181]; auditory receptor cell fate commitment [GO:0009912]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; branching morphogenesis of an epithelial tube [GO:0048754]; calcium-ion regulated exocytosis [GO:0017156]; cardiac atrium morphogenesis [GO:0003209]; cardiac chamber formation [GO:0003207]; cardiac epithelial to mesenchymal transition [GO:0060317]; cardiac left ventricle morphogenesis [GO:0003214]; cardiac muscle cell myoblast differentiation [GO:0060379]; cardiac muscle cell proliferation [GO:0060038]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac right atrium morphogenesis [GO:0003213]; cardiac right ventricle formation [GO:0003219]; cardiac septum morphogenesis [GO:0060411]; cardiac vascular smooth muscle cell development [GO:0060948]; cardiac ventricle morphogenesis [GO:0003208]; cell differentiation [GO:0030154]; cell differentiation in spinal cord [GO:0021515]; cell migration involved in endocardial cushion formation [GO:0003273]; cell population proliferation [GO:0008283]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to hypoxia [GO:0071456]; cellular response to tumor cell [GO:0071228]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cilium assembly [GO:0060271]; collecting duct development [GO:0072044]; compartment pattern specification [GO:0007386]; coronary artery morphogenesis [GO:0060982]; coronary sinus valve morphogenesis [GO:0003182]; coronary vein morphogenesis [GO:0003169]; determination of left/right symmetry [GO:0007368]; distal tubule development [GO:0072017]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; endocardial cell differentiation [GO:0060956]; endocardial cushion development [GO:0003197]; endocardial cushion morphogenesis [GO:0003203]; endocardium development [GO:0003157]; endocardium morphogenesis [GO:0003160]; endoderm development [GO:0007492]; epidermal cell fate specification [GO:0009957]; epidermis development [GO:0008544]; epithelial cell fate commitment [GO:0072148]; epithelial cell proliferation [GO:0050673]; epithelial to mesenchymal transition [GO:0001837]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; forebrain development [GO:0030900]; foregut morphogenesis [GO:0007440]; gene expression [GO:0010467]; glial cell differentiation [GO:0010001]; glomerular mesangial cell development [GO:0072144]; growth involved in heart morphogenesis [GO:0003241]; hair follicle morphogenesis [GO:0031069]; heart development [GO:0007507]; heart looping [GO:0001947]; heart trabecula morphogenesis [GO:0061384]; homeostasis of number of cells within a tissue [GO:0048873]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; inhibition of neuroepithelial cell differentiation [GO:0002085]; interleukin-17-mediated signaling pathway [GO:0097400]; keratinocyte differentiation [GO:0030216]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; lung development [GO:0030324]; mesenchymal cell development [GO:0014031]; mitral valve formation [GO:0003192]; negative regulation of anoikis [GO:2000811]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of catalytic activity [GO:0043086]; negative regulation of cell adhesion molecule production [GO:0060354]; negative regulation of cell death [GO:0060548]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell proliferation involved in heart valve morphogenesis [GO:0003252]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of endothelial cell chemotaxis [GO:2001027]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of extracellular matrix constituent secretion [GO:0003332]; negative regulation of gene expression [GO:0010629]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of inner ear auditory receptor cell differentiation [GO:0045608]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of ossification [GO:0030279]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of photoreceptor cell differentiation [GO:0046533]; negative regulation of pro-B cell differentiation [GO:2000974]; negative regulation of stem cell differentiation [GO:2000737]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube development [GO:0021915]; neuroendocrine cell differentiation [GO:0061101]; neuron differentiation [GO:0030182]; neuron fate commitment [GO:0048663]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation [GO:0003270]; oligodendrocyte differentiation [GO:0048709]; osteoblast fate commitment [GO:0002051]; outflow tract morphogenesis [GO:0003151]; pericardium morphogenesis [GO:0003344]; positive regulation of aorta morphogenesis [GO:1903849]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic process involved in morphogenesis [GO:1902339]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac epithelial to mesenchymal transition [GO:0062043]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of ephrin receptor signaling pathway [GO:1901189]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell differentiation [GO:0045687]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of viral genome replication [GO:0045070]; positive regulation of viral transcription [GO:0050434]; prostate gland epithelium morphogenesis [GO:0060740]; protein catabolic process [GO:0030163]; protein import into nucleus [GO:0006606]; pulmonary valve morphogenesis [GO:0003184]; regulation of cardioblast proliferation [GO:0003264]; regulation of cell adhesion involved in heart morphogenesis [GO:0061344]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127]; regulation of epithelial cell proliferation [GO:0050678]; regulation of epithelial cell proliferation involved in prostate gland development [GO:0060768]; regulation of extracellular matrix assembly [GO:1901201]; regulation of gene expression [GO:0010468]; regulation of inner ear auditory receptor cell differentiation [GO:0045607]; regulation of neurogenesis [GO:0050767]; regulation of Notch signaling pathway [GO:0008593]; regulation of somitogenesis [GO:0014807]; regulation of stem cell proliferation [GO:0072091]; regulation of transcription by RNA polymerase II [GO:0006357]; response to corticosteroid [GO:0031960]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; retinal cone cell differentiation [GO:0042670]; secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development [GO:0060528]; skeletal muscle cell differentiation [GO:0035914]; somatic stem cell division [GO:0048103]; spermatogenesis [GO:0007283]; sprouting angiogenesis [GO:0002040]; T-helper 17 type immune response [GO:0072538]; tissue regeneration [GO:0042246]; transcription by RNA polymerase II [GO:0006366]; tube formation [GO:0035148]; vasculogenesis involved in coronary vascular morphogenesis [GO:0060979]; venous blood vessel morphogenesis [GO:0048845]; venous endothelial cell differentiation [GO:0060843]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222] GO:0000122; GO:0000139; GO:0001669; GO:0001701; GO:0001726; GO:0001837; GO:0001889; GO:0001947; GO:0002040; GO:0002051; GO:0002052; GO:0002085; GO:0002193; GO:0002437; GO:0003151; GO:0003157; GO:0003160; GO:0003162; GO:0003169; GO:0003180; GO:0003181; GO:0003182; GO:0003184; GO:0003192; GO:0003197; GO:0003198; GO:0003203; GO:0003207; GO:0003208; GO:0003209; GO:0003213; GO:0003214; GO:0003219; GO:0003222; GO:0003241; GO:0003252; GO:0003264; GO:0003270; GO:0003273; GO:0003332; GO:0003344; GO:0003682; GO:0003713; GO:0004857; GO:0004888; GO:0005112; GO:0005509; GO:0005576; GO:0005634; GO:0005654; GO:0005737; GO:0005783; GO:0005789; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0005912; GO:0006357; GO:0006366; GO:0006606; GO:0006915; GO:0006959; GO:0007219; GO:0007221; GO:0007283; GO:0007368; GO:0007386; GO:0007409; GO:0007411; GO:0007440; GO:0007492; GO:0007507; GO:0008283; GO:0008284; GO:0008285; GO:0008544; GO:0008593; GO:0009912; GO:0009957; GO:0009986; GO:0010001; GO:0010467; GO:0010468; GO:0010614; GO:0010628; GO:0010629; GO:0010718; GO:0010812; GO:0010832; GO:0014031; GO:0014807; GO:0016324; GO:0017156; GO:0019899; GO:0021515; GO:0021915; GO:0030027; GO:0030154; GO:0030163; GO:0030182; GO:0030216; GO:0030279; GO:0030324; GO:0030326; GO:0030334; GO:0030335; GO:0030513; GO:0030514; GO:0030900; GO:0031069; GO:0031100; GO:0031410; GO:0031490; GO:0031960; GO:0032495; GO:0032496; GO:0032966; GO:0035116; GO:0035148; GO:0035914; GO:0035924; GO:0042127; GO:0042246; GO:0042670; GO:0042802; GO:0043065; GO:0043086; GO:0043235; GO:0045070; GO:0045603; GO:0045607; GO:0045608; GO:0045618; GO:0045662; GO:0045665; GO:0045668; GO:0045687; GO:0045747; GO:0045892; GO:0045893; GO:0045944; GO:0045955; GO:0046427; GO:0046533; GO:0046579; GO:0048103; GO:0048663; GO:0048708; GO:0048709; GO:0048711; GO:0048715; GO:0048754; GO:0048845; GO:0048873; GO:0050434; GO:0050673; GO:0050678; GO:0050679; GO:0050680; GO:0050767; GO:0050768; GO:0055008; GO:0060038; GO:0060045; GO:0060253; GO:0060271; GO:0060317; GO:0060354; GO:0060379; GO:0060411; GO:0060412; GO:0060528; GO:0060548; GO:0060740; GO:0060768; GO:0060842; GO:0060843; GO:0060948; GO:0060956; GO:0060979; GO:0060982; GO:0061101; GO:0061314; GO:0061344; GO:0061384; GO:0062043; GO:0070168; GO:0070374; GO:0070986; GO:0071228; GO:0071372; GO:0071456; GO:0071944; GO:0072017; GO:0072044; GO:0072091; GO:0072144; GO:0072148; GO:0072538; GO:0090051; GO:0090090; GO:0097150; GO:0097400; GO:0120163; GO:0140537; GO:1901189; GO:1901201; GO:1902263; GO:1902339; GO:1903849; GO:2000048; GO:2000737; GO:2000811; GO:2000974; GO:2001027 26014 XM_029334427.2 264 288 304 278 796 Q01705 1.09e-91 Neurogenic locus notch homolog protein 1 (Notch 1) (Motch A) (mT14) (p300) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)] Mus musculus (Mouse) animal organ regeneration [GO:0031100]; aortic valve morphogenesis [GO:0003180]; apoptotic process [GO:0006915]; apoptotic process involved in embryonic digit morphogenesis [GO:1902263]; arterial endothelial cell differentiation [GO:0060842]; astrocyte differentiation [GO:0048708]; atrioventricular node development [GO:0003162]; atrioventricular valve morphogenesis [GO:0003181]; auditory receptor cell fate commitment [GO:0009912]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; branching morphogenesis of an epithelial tube [GO:0048754]; calcium-ion regulated exocytosis [GO:0017156]; cardiac atrium morphogenesis [GO:0003209]; cardiac chamber formation [GO:0003207]; cardiac epithelial to mesenchymal transition [GO:0060317]; cardiac left ventricle morphogenesis [GO:0003214]; cardiac muscle cell myoblast differentiation [GO:0060379]; cardiac muscle cell proliferation [GO:0060038]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac right atrium morphogenesis [GO:0003213]; cardiac right ventricle formation [GO:0003219]; cardiac septum morphogenesis [GO:0060411]; cardiac vascular smooth muscle cell development [GO:0060948]; cardiac ventricle morphogenesis [GO:0003208]; cell differentiation [GO:0030154]; cell differentiation in spinal cord [GO:0021515]; cell migration involved in endocardial cushion formation [GO:0003273]; cell population proliferation [GO:0008283]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to hypoxia [GO:0071456]; cellular response to tumor cell [GO:0071228]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cilium assembly [GO:0060271]; collecting duct development [GO:0072044]; compartment pattern specification [GO:0007386]; coronary artery morphogenesis [GO:0060982]; coronary sinus valve morphogenesis [GO:0003182]; coronary vein morphogenesis [GO:0003169]; determination of left/right symmetry [GO:0007368]; distal tubule development [GO:0072017]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; endocardial cell differentiation [GO:0060956]; endocardial cushion development [GO:0003197]; endocardial cushion morphogenesis [GO:0003203]; endocardium development [GO:0003157]; endocardium morphogenesis [GO:0003160]; endoderm development [GO:0007492]; epidermal cell fate specification [GO:0009957]; epidermis development [GO:0008544]; epithelial cell fate commitment [GO:0072148]; epithelial cell proliferation [GO:0050673]; epithelial to mesenchymal transition [GO:0001837]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; forebrain development [GO:0030900]; foregut morphogenesis [GO:0007440]; gene expression [GO:0010467]; glial cell differentiation [GO:0010001]; glomerular mesangial cell development [GO:0072144]; growth involved in heart morphogenesis [GO:0003241]; hair follicle morphogenesis [GO:0031069]; heart development [GO:0007507]; heart looping [GO:0001947]; heart trabecula morphogenesis [GO:0061384]; homeostasis of number of cells within a tissue [GO:0048873]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; inhibition of neuroepithelial cell differentiation [GO:0002085]; interleukin-17-mediated signaling pathway [GO:0097400]; keratinocyte differentiation [GO:0030216]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; lung development [GO:0030324]; mesenchymal cell development [GO:0014031]; mitral valve formation [GO:0003192]; negative regulation of anoikis [GO:2000811]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of catalytic activity [GO:0043086]; negative regulation of cell adhesion molecule production [GO:0060354]; negative regulation of cell death [GO:0060548]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell proliferation involved in heart valve morphogenesis [GO:0003252]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of endothelial cell chemotaxis [GO:2001027]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of extracellular matrix constituent secretion [GO:0003332]; negative regulation of gene expression [GO:0010629]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of inner ear auditory receptor cell differentiation [GO:0045608]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of ossification [GO:0030279]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of photoreceptor cell differentiation [GO:0046533]; negative regulation of pro-B cell differentiation [GO:2000974]; negative regulation of stem cell differentiation [GO:2000737]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube development [GO:0021915]; neuroendocrine cell differentiation [GO:0061101]; neuron differentiation [GO:0030182]; neuron fate commitment [GO:0048663]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation [GO:0003270]; oligodendrocyte differentiation [GO:0048709]; osteoblast fate commitment [GO:0002051]; outflow tract morphogenesis [GO:0003151]; pericardium morphogenesis [GO:0003344]; positive regulation of aorta morphogenesis [GO:1903849]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic process involved in morphogenesis [GO:1902339]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac epithelial to mesenchymal transition [GO:0062043]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of ephrin receptor signaling pathway [GO:1901189]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell differentiation [GO:0045687]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of viral genome replication [GO:0045070]; positive regulation of viral transcription [GO:0050434]; prostate gland epithelium morphogenesis [GO:0060740]; protein catabolic process [GO:0030163]; protein import into nucleus [GO:0006606]; pulmonary valve morphogenesis [GO:0003184]; regulation of cardioblast proliferation [GO:0003264]; regulation of cell adhesion involved in heart morphogenesis [GO:0061344]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127]; regulation of epithelial cell proliferation [GO:0050678]; regulation of epithelial cell proliferation involved in prostate gland development [GO:0060768]; regulation of extracellular matrix assembly [GO:1901201]; regulation of gene expression [GO:0010468]; regulation of inner ear auditory receptor cell differentiation [GO:0045607]; regulation of neurogenesis [GO:0050767]; regulation of Notch signaling pathway [GO:0008593]; regulation of somitogenesis [GO:0014807]; regulation of stem cell proliferation [GO:0072091]; regulation of transcription by RNA polymerase II [GO:0006357]; response to corticosteroid [GO:0031960]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; retinal cone cell differentiation [GO:0042670]; secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development [GO:0060528]; skeletal muscle cell differentiation [GO:0035914]; somatic stem cell division [GO:0048103]; spermatogenesis [GO:0007283]; sprouting angiogenesis [GO:0002040]; T-helper 17 type immune response [GO:0072538]; tissue regeneration [GO:0042246]; transcription by RNA polymerase II [GO:0006366]; tube formation [GO:0035148]; vasculogenesis involved in coronary vascular morphogenesis [GO:0060979]; venous blood vessel morphogenesis [GO:0048845]; venous endothelial cell differentiation [GO:0060843]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222] GO:0000122; GO:0000139; GO:0001669; GO:0001701; GO:0001726; GO:0001837; GO:0001889; GO:0001947; GO:0002040; GO:0002051; GO:0002052; GO:0002085; GO:0002193; GO:0002437; GO:0003151; GO:0003157; GO:0003160; GO:0003162; GO:0003169; GO:0003180; GO:0003181; GO:0003182; GO:0003184; GO:0003192; GO:0003197; GO:0003198; GO:0003203; GO:0003207; GO:0003208; GO:0003209; GO:0003213; GO:0003214; GO:0003219; GO:0003222; GO:0003241; GO:0003252; GO:0003264; GO:0003270; GO:0003273; GO:0003332; GO:0003344; GO:0003682; GO:0003713; GO:0004857; GO:0004888; GO:0005112; GO:0005509; GO:0005576; GO:0005634; GO:0005654; GO:0005737; GO:0005783; GO:0005789; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0005912; GO:0006357; GO:0006366; GO:0006606; GO:0006915; GO:0006959; GO:0007219; GO:0007221; GO:0007283; GO:0007368; GO:0007386; GO:0007409; GO:0007411; GO:0007440; GO:0007492; GO:0007507; GO:0008283; GO:0008284; GO:0008285; GO:0008544; GO:0008593; GO:0009912; GO:0009957; GO:0009986; GO:0010001; GO:0010467; GO:0010468; GO:0010614; GO:0010628; GO:0010629; GO:0010718; GO:0010812; GO:0010832; GO:0014031; GO:0014807; GO:0016324; GO:0017156; GO:0019899; GO:0021515; GO:0021915; GO:0030027; GO:0030154; GO:0030163; GO:0030182; GO:0030216; GO:0030279; GO:0030324; GO:0030326; GO:0030334; GO:0030335; GO:0030513; GO:0030514; GO:0030900; GO:0031069; GO:0031100; GO:0031410; GO:0031490; GO:0031960; GO:0032495; GO:0032496; GO:0032966; GO:0035116; GO:0035148; GO:0035914; GO:0035924; GO:0042127; GO:0042246; GO:0042670; GO:0042802; GO:0043065; GO:0043086; GO:0043235; GO:0045070; GO:0045603; GO:0045607; GO:0045608; GO:0045618; GO:0045662; GO:0045665; GO:0045668; GO:0045687; GO:0045747; GO:0045892; GO:0045893; GO:0045944; GO:0045955; GO:0046427; GO:0046533; GO:0046579; GO:0048103; GO:0048663; GO:0048708; GO:0048709; GO:0048711; GO:0048715; GO:0048754; GO:0048845; GO:0048873; GO:0050434; GO:0050673; GO:0050678; GO:0050679; GO:0050680; GO:0050767; GO:0050768; GO:0055008; GO:0060038; GO:0060045; GO:0060253; GO:0060271; GO:0060317; GO:0060354; GO:0060379; GO:0060411; GO:0060412; GO:0060528; GO:0060548; GO:0060740; GO:0060768; GO:0060842; GO:0060843; GO:0060948; GO:0060956; GO:0060979; GO:0060982; GO:0061101; GO:0061314; GO:0061344; GO:0061384; GO:0062043; GO:0070168; GO:0070374; GO:0070986; GO:0071228; GO:0071372; GO:0071456; GO:0071944; GO:0072017; GO:0072044; GO:0072091; GO:0072144; GO:0072148; GO:0072538; GO:0090051; GO:0090090; GO:0097150; GO:0097400; GO:0120163; GO:0140537; GO:1901189; GO:1901201; GO:1902263; GO:1902339; GO:1903849; GO:2000048; GO:2000737; GO:2000811; GO:2000974; GO:2001027 26015 XM_029334427.2 264 288 304 278 796 Q01705 1.95e-88 Neurogenic locus notch homolog protein 1 (Notch 1) (Motch A) (mT14) (p300) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)] Mus musculus (Mouse) animal organ regeneration [GO:0031100]; aortic valve morphogenesis [GO:0003180]; apoptotic process [GO:0006915]; apoptotic process involved in embryonic digit morphogenesis [GO:1902263]; arterial endothelial cell differentiation [GO:0060842]; astrocyte differentiation [GO:0048708]; atrioventricular node development [GO:0003162]; atrioventricular valve morphogenesis [GO:0003181]; auditory receptor cell fate commitment [GO:0009912]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; branching morphogenesis of an epithelial tube [GO:0048754]; calcium-ion regulated exocytosis [GO:0017156]; cardiac atrium morphogenesis [GO:0003209]; cardiac chamber formation [GO:0003207]; cardiac epithelial to mesenchymal transition [GO:0060317]; cardiac left ventricle morphogenesis [GO:0003214]; cardiac muscle cell myoblast differentiation [GO:0060379]; cardiac muscle cell proliferation [GO:0060038]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac right atrium morphogenesis [GO:0003213]; cardiac right ventricle formation [GO:0003219]; cardiac septum morphogenesis [GO:0060411]; cardiac vascular smooth muscle cell development [GO:0060948]; cardiac ventricle morphogenesis [GO:0003208]; cell differentiation [GO:0030154]; cell differentiation in spinal cord [GO:0021515]; cell migration involved in endocardial cushion formation [GO:0003273]; cell population proliferation [GO:0008283]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to hypoxia [GO:0071456]; cellular response to tumor cell [GO:0071228]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cilium assembly [GO:0060271]; collecting duct development [GO:0072044]; compartment pattern specification [GO:0007386]; coronary artery morphogenesis [GO:0060982]; coronary sinus valve morphogenesis [GO:0003182]; coronary vein morphogenesis [GO:0003169]; determination of left/right symmetry [GO:0007368]; distal tubule development [GO:0072017]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; endocardial cell differentiation [GO:0060956]; endocardial cushion development [GO:0003197]; endocardial cushion morphogenesis [GO:0003203]; endocardium development [GO:0003157]; endocardium morphogenesis [GO:0003160]; endoderm development [GO:0007492]; epidermal cell fate specification [GO:0009957]; epidermis development [GO:0008544]; epithelial cell fate commitment [GO:0072148]; epithelial cell proliferation [GO:0050673]; epithelial to mesenchymal transition [GO:0001837]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; forebrain development [GO:0030900]; foregut morphogenesis [GO:0007440]; gene expression [GO:0010467]; glial cell differentiation [GO:0010001]; glomerular mesangial cell development [GO:0072144]; growth involved in heart morphogenesis [GO:0003241]; hair follicle morphogenesis [GO:0031069]; heart development [GO:0007507]; heart looping [GO:0001947]; heart trabecula morphogenesis [GO:0061384]; homeostasis of number of cells within a tissue [GO:0048873]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; inhibition of neuroepithelial cell differentiation [GO:0002085]; interleukin-17-mediated signaling pathway [GO:0097400]; keratinocyte differentiation [GO:0030216]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; lung development [GO:0030324]; mesenchymal cell development [GO:0014031]; mitral valve formation [GO:0003192]; negative regulation of anoikis [GO:2000811]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of catalytic activity [GO:0043086]; negative regulation of cell adhesion molecule production [GO:0060354]; negative regulation of cell death [GO:0060548]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell proliferation involved in heart valve morphogenesis [GO:0003252]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of endothelial cell chemotaxis [GO:2001027]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of extracellular matrix constituent secretion [GO:0003332]; negative regulation of gene expression [GO:0010629]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of inner ear auditory receptor cell differentiation [GO:0045608]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of ossification [GO:0030279]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of photoreceptor cell differentiation [GO:0046533]; negative regulation of pro-B cell differentiation [GO:2000974]; negative regulation of stem cell differentiation [GO:2000737]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube development [GO:0021915]; neuroendocrine cell differentiation [GO:0061101]; neuron differentiation [GO:0030182]; neuron fate commitment [GO:0048663]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation [GO:0003270]; oligodendrocyte differentiation [GO:0048709]; osteoblast fate commitment [GO:0002051]; outflow tract morphogenesis [GO:0003151]; pericardium morphogenesis [GO:0003344]; positive regulation of aorta morphogenesis [GO:1903849]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic process involved in morphogenesis [GO:1902339]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac epithelial to mesenchymal transition [GO:0062043]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of ephrin receptor signaling pathway [GO:1901189]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell differentiation [GO:0045687]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of viral genome replication [GO:0045070]; positive regulation of viral transcription [GO:0050434]; prostate gland epithelium morphogenesis [GO:0060740]; protein catabolic process [GO:0030163]; protein import into nucleus [GO:0006606]; pulmonary valve morphogenesis [GO:0003184]; regulation of cardioblast proliferation [GO:0003264]; regulation of cell adhesion involved in heart morphogenesis [GO:0061344]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127]; regulation of epithelial cell proliferation [GO:0050678]; regulation of epithelial cell proliferation involved in prostate gland development [GO:0060768]; regulation of extracellular matrix assembly [GO:1901201]; regulation of gene expression [GO:0010468]; regulation of inner ear auditory receptor cell differentiation [GO:0045607]; regulation of neurogenesis [GO:0050767]; regulation of Notch signaling pathway [GO:0008593]; regulation of somitogenesis [GO:0014807]; regulation of stem cell proliferation [GO:0072091]; regulation of transcription by RNA polymerase II [GO:0006357]; response to corticosteroid [GO:0031960]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; retinal cone cell differentiation [GO:0042670]; secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development [GO:0060528]; skeletal muscle cell differentiation [GO:0035914]; somatic stem cell division [GO:0048103]; spermatogenesis [GO:0007283]; sprouting angiogenesis [GO:0002040]; T-helper 17 type immune response [GO:0072538]; tissue regeneration [GO:0042246]; transcription by RNA polymerase II [GO:0006366]; tube formation [GO:0035148]; vasculogenesis involved in coronary vascular morphogenesis [GO:0060979]; venous blood vessel morphogenesis [GO:0048845]; venous endothelial cell differentiation [GO:0060843]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222] GO:0000122; GO:0000139; GO:0001669; GO:0001701; GO:0001726; GO:0001837; GO:0001889; GO:0001947; GO:0002040; GO:0002051; GO:0002052; GO:0002085; GO:0002193; GO:0002437; GO:0003151; GO:0003157; GO:0003160; GO:0003162; GO:0003169; GO:0003180; GO:0003181; GO:0003182; GO:0003184; GO:0003192; GO:0003197; GO:0003198; GO:0003203; GO:0003207; GO:0003208; GO:0003209; GO:0003213; GO:0003214; GO:0003219; GO:0003222; GO:0003241; GO:0003252; GO:0003264; GO:0003270; GO:0003273; GO:0003332; GO:0003344; GO:0003682; GO:0003713; GO:0004857; GO:0004888; GO:0005112; GO:0005509; GO:0005576; GO:0005634; GO:0005654; GO:0005737; GO:0005783; GO:0005789; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0005912; GO:0006357; GO:0006366; GO:0006606; GO:0006915; GO:0006959; GO:0007219; GO:0007221; GO:0007283; GO:0007368; GO:0007386; GO:0007409; GO:0007411; GO:0007440; GO:0007492; GO:0007507; GO:0008283; GO:0008284; GO:0008285; GO:0008544; GO:0008593; GO:0009912; GO:0009957; GO:0009986; GO:0010001; GO:0010467; GO:0010468; GO:0010614; GO:0010628; GO:0010629; GO:0010718; GO:0010812; GO:0010832; GO:0014031; GO:0014807; GO:0016324; GO:0017156; GO:0019899; GO:0021515; GO:0021915; GO:0030027; GO:0030154; GO:0030163; GO:0030182; GO:0030216; GO:0030279; GO:0030324; GO:0030326; GO:0030334; GO:0030335; GO:0030513; GO:0030514; GO:0030900; GO:0031069; GO:0031100; GO:0031410; GO:0031490; GO:0031960; GO:0032495; GO:0032496; GO:0032966; GO:0035116; GO:0035148; GO:0035914; GO:0035924; GO:0042127; GO:0042246; GO:0042670; GO:0042802; GO:0043065; GO:0043086; GO:0043235; GO:0045070; GO:0045603; GO:0045607; GO:0045608; GO:0045618; GO:0045662; GO:0045665; GO:0045668; GO:0045687; GO:0045747; GO:0045892; GO:0045893; GO:0045944; GO:0045955; GO:0046427; GO:0046533; GO:0046579; GO:0048103; GO:0048663; GO:0048708; GO:0048709; GO:0048711; GO:0048715; GO:0048754; GO:0048845; GO:0048873; GO:0050434; GO:0050673; GO:0050678; GO:0050679; GO:0050680; GO:0050767; GO:0050768; GO:0055008; GO:0060038; GO:0060045; GO:0060253; GO:0060271; GO:0060317; GO:0060354; GO:0060379; GO:0060411; GO:0060412; GO:0060528; GO:0060548; GO:0060740; GO:0060768; GO:0060842; GO:0060843; GO:0060948; GO:0060956; GO:0060979; GO:0060982; GO:0061101; GO:0061314; GO:0061344; GO:0061384; GO:0062043; GO:0070168; GO:0070374; GO:0070986; GO:0071228; GO:0071372; GO:0071456; GO:0071944; GO:0072017; GO:0072044; GO:0072091; GO:0072144; GO:0072148; GO:0072538; GO:0090051; GO:0090090; GO:0097150; GO:0097400; GO:0120163; GO:0140537; GO:1901189; GO:1901201; GO:1902263; GO:1902339; GO:1903849; GO:2000048; GO:2000737; GO:2000811; GO:2000974; GO:2001027 26016 XM_029334427.2 264 288 304 278 796 Q01705 5.36e-84 Neurogenic locus notch homolog protein 1 (Notch 1) (Motch A) (mT14) (p300) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)] Mus musculus (Mouse) animal organ regeneration [GO:0031100]; aortic valve morphogenesis [GO:0003180]; apoptotic process [GO:0006915]; apoptotic process involved in embryonic digit morphogenesis [GO:1902263]; arterial endothelial cell differentiation [GO:0060842]; astrocyte differentiation [GO:0048708]; atrioventricular node development [GO:0003162]; atrioventricular valve morphogenesis [GO:0003181]; auditory receptor cell fate commitment [GO:0009912]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; branching morphogenesis of an epithelial tube [GO:0048754]; calcium-ion regulated exocytosis [GO:0017156]; cardiac atrium morphogenesis [GO:0003209]; cardiac chamber formation [GO:0003207]; cardiac epithelial to mesenchymal transition [GO:0060317]; cardiac left ventricle morphogenesis [GO:0003214]; cardiac muscle cell myoblast differentiation [GO:0060379]; cardiac muscle cell proliferation [GO:0060038]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac right atrium morphogenesis [GO:0003213]; cardiac right ventricle formation [GO:0003219]; cardiac septum morphogenesis [GO:0060411]; cardiac vascular smooth muscle cell development [GO:0060948]; cardiac ventricle morphogenesis [GO:0003208]; cell differentiation [GO:0030154]; cell differentiation in spinal cord [GO:0021515]; cell migration involved in endocardial cushion formation [GO:0003273]; cell population proliferation [GO:0008283]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to hypoxia [GO:0071456]; cellular response to tumor cell [GO:0071228]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cilium assembly [GO:0060271]; collecting duct development [GO:0072044]; compartment pattern specification [GO:0007386]; coronary artery morphogenesis [GO:0060982]; coronary sinus valve morphogenesis [GO:0003182]; coronary vein morphogenesis [GO:0003169]; determination of left/right symmetry [GO:0007368]; distal tubule development [GO:0072017]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; endocardial cell differentiation [GO:0060956]; endocardial cushion development [GO:0003197]; endocardial cushion morphogenesis [GO:0003203]; endocardium development [GO:0003157]; endocardium morphogenesis [GO:0003160]; endoderm development [GO:0007492]; epidermal cell fate specification [GO:0009957]; epidermis development [GO:0008544]; epithelial cell fate commitment [GO:0072148]; epithelial cell proliferation [GO:0050673]; epithelial to mesenchymal transition [GO:0001837]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; forebrain development [GO:0030900]; foregut morphogenesis [GO:0007440]; gene expression [GO:0010467]; glial cell differentiation [GO:0010001]; glomerular mesangial cell development [GO:0072144]; growth involved in heart morphogenesis [GO:0003241]; hair follicle morphogenesis [GO:0031069]; heart development [GO:0007507]; heart looping [GO:0001947]; heart trabecula morphogenesis [GO:0061384]; homeostasis of number of cells within a tissue [GO:0048873]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; inhibition of neuroepithelial cell differentiation [GO:0002085]; interleukin-17-mediated signaling pathway [GO:0097400]; keratinocyte differentiation [GO:0030216]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; lung development [GO:0030324]; mesenchymal cell development [GO:0014031]; mitral valve formation [GO:0003192]; negative regulation of anoikis [GO:2000811]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of catalytic activity [GO:0043086]; negative regulation of cell adhesion molecule production [GO:0060354]; negative regulation of cell death [GO:0060548]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell proliferation involved in heart valve morphogenesis [GO:0003252]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of endothelial cell chemotaxis [GO:2001027]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of extracellular matrix constituent secretion [GO:0003332]; negative regulation of gene expression [GO:0010629]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of inner ear auditory receptor cell differentiation [GO:0045608]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of ossification [GO:0030279]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of photoreceptor cell differentiation [GO:0046533]; negative regulation of pro-B cell differentiation [GO:2000974]; negative regulation of stem cell differentiation [GO:2000737]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube development [GO:0021915]; neuroendocrine cell differentiation [GO:0061101]; neuron differentiation [GO:0030182]; neuron fate commitment [GO:0048663]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation [GO:0003270]; oligodendrocyte differentiation [GO:0048709]; osteoblast fate commitment [GO:0002051]; outflow tract morphogenesis [GO:0003151]; pericardium morphogenesis [GO:0003344]; positive regulation of aorta morphogenesis [GO:1903849]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic process involved in morphogenesis [GO:1902339]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac epithelial to mesenchymal transition [GO:0062043]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of ephrin receptor signaling pathway [GO:1901189]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell differentiation [GO:0045687]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of viral genome replication [GO:0045070]; positive regulation of viral transcription [GO:0050434]; prostate gland epithelium morphogenesis [GO:0060740]; protein catabolic process [GO:0030163]; protein import into nucleus [GO:0006606]; pulmonary valve morphogenesis [GO:0003184]; regulation of cardioblast proliferation [GO:0003264]; regulation of cell adhesion involved in heart morphogenesis [GO:0061344]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127]; regulation of epithelial cell proliferation [GO:0050678]; regulation of epithelial cell proliferation involved in prostate gland development [GO:0060768]; regulation of extracellular matrix assembly [GO:1901201]; regulation of gene expression [GO:0010468]; regulation of inner ear auditory receptor cell differentiation [GO:0045607]; regulation of neurogenesis [GO:0050767]; regulation of Notch signaling pathway [GO:0008593]; regulation of somitogenesis [GO:0014807]; regulation of stem cell proliferation [GO:0072091]; regulation of transcription by RNA polymerase II [GO:0006357]; response to corticosteroid [GO:0031960]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; retinal cone cell differentiation [GO:0042670]; secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development [GO:0060528]; skeletal muscle cell differentiation [GO:0035914]; somatic stem cell division [GO:0048103]; spermatogenesis [GO:0007283]; sprouting angiogenesis [GO:0002040]; T-helper 17 type immune response [GO:0072538]; tissue regeneration [GO:0042246]; transcription by RNA polymerase II [GO:0006366]; tube formation [GO:0035148]; vasculogenesis involved in coronary vascular morphogenesis [GO:0060979]; venous blood vessel morphogenesis [GO:0048845]; venous endothelial cell differentiation [GO:0060843]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222] GO:0000122; GO:0000139; GO:0001669; GO:0001701; GO:0001726; GO:0001837; GO:0001889; GO:0001947; GO:0002040; GO:0002051; GO:0002052; GO:0002085; GO:0002193; GO:0002437; GO:0003151; GO:0003157; GO:0003160; GO:0003162; GO:0003169; GO:0003180; GO:0003181; GO:0003182; GO:0003184; GO:0003192; GO:0003197; GO:0003198; GO:0003203; GO:0003207; GO:0003208; GO:0003209; GO:0003213; GO:0003214; GO:0003219; GO:0003222; GO:0003241; GO:0003252; GO:0003264; GO:0003270; GO:0003273; GO:0003332; GO:0003344; GO:0003682; GO:0003713; GO:0004857; GO:0004888; GO:0005112; GO:0005509; GO:0005576; GO:0005634; GO:0005654; GO:0005737; GO:0005783; GO:0005789; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0005912; GO:0006357; GO:0006366; GO:0006606; GO:0006915; GO:0006959; GO:0007219; GO:0007221; GO:0007283; GO:0007368; GO:0007386; GO:0007409; GO:0007411; GO:0007440; GO:0007492; GO:0007507; GO:0008283; GO:0008284; GO:0008285; GO:0008544; GO:0008593; GO:0009912; GO:0009957; GO:0009986; GO:0010001; GO:0010467; GO:0010468; GO:0010614; GO:0010628; GO:0010629; GO:0010718; GO:0010812; GO:0010832; GO:0014031; GO:0014807; GO:0016324; GO:0017156; GO:0019899; GO:0021515; GO:0021915; GO:0030027; GO:0030154; GO:0030163; GO:0030182; GO:0030216; GO:0030279; GO:0030324; GO:0030326; GO:0030334; GO:0030335; GO:0030513; GO:0030514; GO:0030900; GO:0031069; GO:0031100; GO:0031410; GO:0031490; GO:0031960; GO:0032495; GO:0032496; GO:0032966; GO:0035116; GO:0035148; GO:0035914; GO:0035924; GO:0042127; GO:0042246; GO:0042670; GO:0042802; GO:0043065; GO:0043086; GO:0043235; GO:0045070; GO:0045603; GO:0045607; GO:0045608; GO:0045618; GO:0045662; GO:0045665; GO:0045668; GO:0045687; GO:0045747; GO:0045892; GO:0045893; GO:0045944; GO:0045955; GO:0046427; GO:0046533; GO:0046579; GO:0048103; GO:0048663; GO:0048708; GO:0048709; GO:0048711; GO:0048715; GO:0048754; GO:0048845; GO:0048873; GO:0050434; GO:0050673; GO:0050678; GO:0050679; GO:0050680; GO:0050767; GO:0050768; GO:0055008; GO:0060038; GO:0060045; GO:0060253; GO:0060271; GO:0060317; GO:0060354; GO:0060379; GO:0060411; GO:0060412; GO:0060528; GO:0060548; GO:0060740; GO:0060768; GO:0060842; GO:0060843; GO:0060948; GO:0060956; GO:0060979; GO:0060982; GO:0061101; GO:0061314; GO:0061344; GO:0061384; GO:0062043; GO:0070168; GO:0070374; GO:0070986; GO:0071228; GO:0071372; GO:0071456; GO:0071944; GO:0072017; GO:0072044; GO:0072091; GO:0072144; GO:0072148; GO:0072538; GO:0090051; GO:0090090; GO:0097150; GO:0097400; GO:0120163; GO:0140537; GO:1901189; GO:1901201; GO:1902263; GO:1902339; GO:1903849; GO:2000048; GO:2000737; GO:2000811; GO:2000974; GO:2001027 26017 XM_029338020.2 917 456 862 1169 1363 Q7YQM4 4.11e-131 Transcriptional regulator ATRX (EC 3.6.4.12) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) Pan troglodytes (Chimpanzee) cellular response to hydroxyurea [GO:0072711]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; chromosome organization involved in meiotic cell cycle [GO:0070192]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA repair [GO:0006281]; forebrain development [GO:0030900]; meiotic spindle organization [GO:0000212]; multicellular organism growth [GO:0035264]; negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric [GO:1904908]; nucleosome assembly [GO:0006334]; positive regulation of nuclear cell cycle DNA replication [GO:0010571]; positive regulation of telomere maintenance [GO:0032206]; positive regulation of telomeric RNA transcription from RNA pol II promoter [GO:1901582]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic forelimb morphogenesis [GO:0035128]; protein localization to chromosome, telomeric region [GO:0070198]; replication fork processing [GO:0031297]; seminiferous tubule development [GO:0072520]; Sertoli cell development [GO:0060009]; spermatogenesis [GO:0007283]; subtelomeric heterochromatin formation [GO:0031509]; transcription by RNA polymerase II [GO:0006366] GO:0000212; GO:0000228; GO:0000779; GO:0000781; GO:0003682; GO:0004386; GO:0005524; GO:0005634; GO:0005721; GO:0006281; GO:0006325; GO:0006334; GO:0006338; GO:0006366; GO:0007283; GO:0010571; GO:0015616; GO:0016605; GO:0016887; GO:0030330; GO:0030900; GO:0031297; GO:0031490; GO:0031509; GO:0032206; GO:0035064; GO:0035128; GO:0035264; GO:0042393; GO:0045944; GO:0046872; GO:0060009; GO:0070087; GO:0070192; GO:0070198; GO:0072520; GO:0072711; GO:0099115; GO:0140658; GO:1901582; GO:1904908 26018 XM_029338020.2 917 456 862 1169 1363 Q7YQM4 5.82e-76 Transcriptional regulator ATRX (EC 3.6.4.12) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) Pan troglodytes (Chimpanzee) cellular response to hydroxyurea [GO:0072711]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; chromosome organization involved in meiotic cell cycle [GO:0070192]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA repair [GO:0006281]; forebrain development [GO:0030900]; meiotic spindle organization [GO:0000212]; multicellular organism growth [GO:0035264]; negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric [GO:1904908]; nucleosome assembly [GO:0006334]; positive regulation of nuclear cell cycle DNA replication [GO:0010571]; positive regulation of telomere maintenance [GO:0032206]; positive regulation of telomeric RNA transcription from RNA pol II promoter [GO:1901582]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic forelimb morphogenesis [GO:0035128]; protein localization to chromosome, telomeric region [GO:0070198]; replication fork processing [GO:0031297]; seminiferous tubule development [GO:0072520]; Sertoli cell development [GO:0060009]; spermatogenesis [GO:0007283]; subtelomeric heterochromatin formation [GO:0031509]; transcription by RNA polymerase II [GO:0006366] GO:0000212; GO:0000228; GO:0000779; GO:0000781; GO:0003682; GO:0004386; GO:0005524; GO:0005634; GO:0005721; GO:0006281; GO:0006325; GO:0006334; GO:0006338; GO:0006366; GO:0007283; GO:0010571; GO:0015616; GO:0016605; GO:0016887; GO:0030330; GO:0030900; GO:0031297; GO:0031490; GO:0031509; GO:0032206; GO:0035064; GO:0035128; GO:0035264; GO:0042393; GO:0045944; GO:0046872; GO:0060009; GO:0070087; GO:0070192; GO:0070198; GO:0072520; GO:0072711; GO:0099115; GO:0140658; GO:1901582; GO:1904908 26019 XM_029338020.2 917 456 862 1169 1363 Q7YQM4 2.74e-31 Transcriptional regulator ATRX (EC 3.6.4.12) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) Pan troglodytes (Chimpanzee) cellular response to hydroxyurea [GO:0072711]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; chromosome organization involved in meiotic cell cycle [GO:0070192]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA repair [GO:0006281]; forebrain development [GO:0030900]; meiotic spindle organization [GO:0000212]; multicellular organism growth [GO:0035264]; negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric [GO:1904908]; nucleosome assembly [GO:0006334]; positive regulation of nuclear cell cycle DNA replication [GO:0010571]; positive regulation of telomere maintenance [GO:0032206]; positive regulation of telomeric RNA transcription from RNA pol II promoter [GO:1901582]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic forelimb morphogenesis [GO:0035128]; protein localization to chromosome, telomeric region [GO:0070198]; replication fork processing [GO:0031297]; seminiferous tubule development [GO:0072520]; Sertoli cell development [GO:0060009]; spermatogenesis [GO:0007283]; subtelomeric heterochromatin formation [GO:0031509]; transcription by RNA polymerase II [GO:0006366] GO:0000212; GO:0000228; GO:0000779; GO:0000781; GO:0003682; GO:0004386; GO:0005524; GO:0005634; GO:0005721; GO:0006281; GO:0006325; GO:0006334; GO:0006338; GO:0006366; GO:0007283; GO:0010571; GO:0015616; GO:0016605; GO:0016887; GO:0030330; GO:0030900; GO:0031297; GO:0031490; GO:0031509; GO:0032206; GO:0035064; GO:0035128; GO:0035264; GO:0042393; GO:0045944; GO:0046872; GO:0060009; GO:0070087; GO:0070192; GO:0070198; GO:0072520; GO:0072711; GO:0099115; GO:0140658; GO:1901582; GO:1904908 26020 XM_044325909.1 9 3 1 6 13 NA NA NA NA NA NA 26021 XM_029329305.2 35341 47539 32048 37178 15614 Q792I0 6.48e-90 Protein lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3) Rattus norvegicus (Rat) exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; morphogenesis of an epithelial sheet [GO:0002011]; neurotransmitter secretion [GO:0007269]; protein localization to basolateral plasma membrane [GO:1903361]; protein transport [GO:0015031] GO:0002011; GO:0005737; GO:0005886; GO:0005911; GO:0005923; GO:0006887; GO:0007269; GO:0008092; GO:0015031; GO:0016020; GO:0016323; GO:0019904; GO:0030165; GO:0045199; GO:0045202; GO:0097016; GO:0097025; GO:0098793; GO:0098839; GO:0098978; GO:1903361 26022 XM_029332316.2 513 696 889 351 622 Q6NXR0 5.66e-45 Interferon-inducible GTPase 5 (EC 3.6.5.-) (Immunity-related GTPase cinema 1) Homo sapiens (Human) cellular response to interferon-beta [GO:0035458]; defense response [GO:0006952] GO:0003924; GO:0005525; GO:0005789; GO:0006952; GO:0035458 26023 XM_044318528.1 29 767 818 402 472 Q9U3S9 1.33e-50 Zinc metalloproteinase nas-6 (EC 3.4.24.-) (Nematode astacin 6) Caenorhabditis elegans pharyngeal pumping [GO:0043050]; pharynx development [GO:0060465]; proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0006508; GO:0008270; GO:0043050; GO:0060465 26024 XM_029352066.2 2302 485 1495 1172 931 Q9Y6R4 2.25e-36 Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAP three kinase 1) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4) Homo sapiens (Human) chorionic trophoblast cell differentiation [GO:0060718]; intracellular signal transduction [GO:0035556]; male germ-line sex determination [GO:0019100]; MAPK cascade [GO:0000165]; placenta development [GO:0001890]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein phosphorylation [GO:0006468]; regulation of gene expression [GO:0010468]; response to UV-C [GO:0010225] GO:0000165; GO:0001890; GO:0004709; GO:0005524; GO:0005737; GO:0006468; GO:0010225; GO:0010468; GO:0019100; GO:0032212; GO:0035556; GO:0043507; GO:0046872; GO:0048471; GO:0051973; GO:0060718; GO:0106310; GO:1900745; GO:1904355 26025 XM_029347787.2 866 862 308 799 839 Q9QXV3 5.86e-66 Inhibitor of growth protein 1 Mus musculus (Mouse) cell cycle [GO:0007049]; negative regulation of cell migration [GO:0030336]; negative regulation of stem cell population maintenance [GO:1902455]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of stem cell population maintenance [GO:1902459]; protein import into nucleus [GO:0006606]; regulation of cell death [GO:0010941]; regulation of DNA-templated transcription [GO:0006355] GO:0000122; GO:0005634; GO:0006355; GO:0006606; GO:0007049; GO:0010941; GO:0016580; GO:0030336; GO:0030512; GO:0035064; GO:0045893; GO:0046872; GO:1902455; GO:1902459 26026 XM_044315202.1 115 107 58 0 37 NA NA NA NA NA NA 26027 XR_003828218.2 311 261 271 312 389 NA NA NA NA NA NA 26028 XM_029355354.2 320 181 72 340 216 A1L1W9 2.39e-79 Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10) Danio rerio (Zebrafish) (Brachydanio rerio) aromatic amino acid transport [GO:0015801]; thyroid hormone transport [GO:0070327] GO:0005302; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0070327 26029 XM_029339192.2 147 63 156 149 243 Q5RF14 0 Mitochondrial intermediate peptidase (MIP) (EC 3.4.24.59) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) proteolysis [GO:0006508] GO:0004222; GO:0005759; GO:0006508; GO:0046872 26030 XM_044326019.1 132 20 42 38 5 Q8CJG0 5.09e-150 Protein argonaute-2 (Argonaute2) (mAgo2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (Piwi/argonaute family protein meIF2C2) (Protein slicer) Mus musculus (Mouse) cell differentiation [GO:0030154]; miRNA metabolic process [GO:0010586]; miRNA processing [GO:0035196]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; miRNA-mediated gene silencing by mRNA destabilization [GO:0035279]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; negative regulation of translational initiation [GO:0045947]; positive regulation of angiogenesis [GO:0045766]; positive regulation of gene expression [GO:0010628]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of trophoblast cell migration [GO:1901165]; post-embryonic development [GO:0009791]; pre-miRNA processing [GO:0031054]; RISC complex assembly [GO:0070922]; RNA secondary structure unwinding [GO:0010501]; RNA-mediated gene silencing [GO:0031047]; siRNA processing [GO:0030422]; siRNA-mediated gene silencing by mRNA destabilization [GO:0090625] GO:0000340; GO:0000932; GO:0000993; GO:0001046; GO:0003723; GO:0003725; GO:0003727; GO:0003729; GO:0004521; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0005844; GO:0005845; GO:0008022; GO:0009791; GO:0010501; GO:0010586; GO:0010628; GO:0016442; GO:0030154; GO:0030422; GO:0030425; GO:0031047; GO:0031054; GO:0035196; GO:0035197; GO:0035198; GO:0035278; GO:0035279; GO:0036464; GO:0042985; GO:0045766; GO:0045944; GO:0045947; GO:0046872; GO:0060213; GO:0070062; GO:0070551; GO:0070578; GO:0070922; GO:0090624; GO:0090625; GO:0098808; GO:1900153; GO:1901165; GO:1990904 26031 XR_006393625.1 86 53 35 121 70 NA NA NA NA NA NA 26032 XM_044310174.1 369 148 211 260 399 Q96AY4 4.2e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26033 XM_044310174.1 369 148 211 260 399 Q96AY4 4.05e-84 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26034 XM_044310174.1 369 148 211 260 399 Q96AY4 3.89e-83 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26035 XM_044310174.1 369 148 211 260 399 Q96AY4 4.54e-82 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26036 XM_044310174.1 369 148 211 260 399 Q96AY4 2.42e-78 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26037 XM_044310174.1 369 148 211 260 399 Q96AY4 5.5e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26038 XM_044310174.1 369 148 211 260 399 Q96AY4 7.96e-65 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26039 XM_044310174.1 369 148 211 260 399 Q96AY4 5.36e-62 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26040 XM_044310174.1 369 148 211 260 399 Q96AY4 5.98e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26041 XM_044310174.1 369 148 211 260 399 Q96AY4 6.76e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26042 XM_029335371.2 992 321 364 528 277 Q3TTY0 1.69e-69 Phospholipase B1, membrane-associated (Phospholipase B) (Lysophospholipase) (EC 3.1.1.5) (Phospholipase A2) (EC 3.1.1.4) (Phospholipase B/lipase) (PLB/LIP) (Triacylglycerol lipase) (EC 3.1.1.3) Mus musculus (Mouse) diacylglycerol catabolic process [GO:0046340]; phosphatidylcholine catabolic process [GO:0034638]; phosphatidylethanolamine catabolic process [GO:0046338]; phosphatidylglycerol catabolic process [GO:0034478]; phospholipid metabolic process [GO:0006644]; positive regulation of acrosome reaction [GO:2000344]; retinol metabolic process [GO:0042572]; triglyceride catabolic process [GO:0019433] GO:0004620; GO:0004622; GO:0004623; GO:0004806; GO:0006644; GO:0016324; GO:0019433; GO:0031526; GO:0034478; GO:0034638; GO:0042572; GO:0046338; GO:0046340; GO:0047499; GO:0050253; GO:0102545; GO:2000344 26043 XM_029335371.2 992 321 364 528 277 Q3TTY0 7.52e-60 Phospholipase B1, membrane-associated (Phospholipase B) (Lysophospholipase) (EC 3.1.1.5) (Phospholipase A2) (EC 3.1.1.4) (Phospholipase B/lipase) (PLB/LIP) (Triacylglycerol lipase) (EC 3.1.1.3) Mus musculus (Mouse) diacylglycerol catabolic process [GO:0046340]; phosphatidylcholine catabolic process [GO:0034638]; phosphatidylethanolamine catabolic process [GO:0046338]; phosphatidylglycerol catabolic process [GO:0034478]; phospholipid metabolic process [GO:0006644]; positive regulation of acrosome reaction [GO:2000344]; retinol metabolic process [GO:0042572]; triglyceride catabolic process [GO:0019433] GO:0004620; GO:0004622; GO:0004623; GO:0004806; GO:0006644; GO:0016324; GO:0019433; GO:0031526; GO:0034478; GO:0034638; GO:0042572; GO:0046338; GO:0046340; GO:0047499; GO:0050253; GO:0102545; GO:2000344 26044 XM_029335371.2 992 321 364 528 277 Q3TTY0 6.47e-59 Phospholipase B1, membrane-associated (Phospholipase B) (Lysophospholipase) (EC 3.1.1.5) (Phospholipase A2) (EC 3.1.1.4) (Phospholipase B/lipase) (PLB/LIP) (Triacylglycerol lipase) (EC 3.1.1.3) Mus musculus (Mouse) diacylglycerol catabolic process [GO:0046340]; phosphatidylcholine catabolic process [GO:0034638]; phosphatidylethanolamine catabolic process [GO:0046338]; phosphatidylglycerol catabolic process [GO:0034478]; phospholipid metabolic process [GO:0006644]; positive regulation of acrosome reaction [GO:2000344]; retinol metabolic process [GO:0042572]; triglyceride catabolic process [GO:0019433] GO:0004620; GO:0004622; GO:0004623; GO:0004806; GO:0006644; GO:0016324; GO:0019433; GO:0031526; GO:0034478; GO:0034638; GO:0042572; GO:0046338; GO:0046340; GO:0047499; GO:0050253; GO:0102545; GO:2000344 26045 XM_029335371.2 992 321 364 528 277 Q3TTY0 1.51e-24 Phospholipase B1, membrane-associated (Phospholipase B) (Lysophospholipase) (EC 3.1.1.5) (Phospholipase A2) (EC 3.1.1.4) (Phospholipase B/lipase) (PLB/LIP) (Triacylglycerol lipase) (EC 3.1.1.3) Mus musculus (Mouse) diacylglycerol catabolic process [GO:0046340]; phosphatidylcholine catabolic process [GO:0034638]; phosphatidylethanolamine catabolic process [GO:0046338]; phosphatidylglycerol catabolic process [GO:0034478]; phospholipid metabolic process [GO:0006644]; positive regulation of acrosome reaction [GO:2000344]; retinol metabolic process [GO:0042572]; triglyceride catabolic process [GO:0019433] GO:0004620; GO:0004622; GO:0004623; GO:0004806; GO:0006644; GO:0016324; GO:0019433; GO:0031526; GO:0034478; GO:0034638; GO:0042572; GO:0046338; GO:0046340; GO:0047499; GO:0050253; GO:0102545; GO:2000344 26046 XM_044324145.1 629 287 56 48 84 NA NA NA NA NA NA 26047 XM_044315162.1 168 158 118 0 98 P20664 1.2e-159 DNA primase small subunit (EC 2.7.7.102) (DNA primase 49 kDa subunit) (p49) Mus musculus (Mouse) DNA replication initiation [GO:0006270]; DNA replication, synthesis of RNA primer [GO:0006269] GO:0000287; GO:0003896; GO:0005658; GO:0006269; GO:0006270; GO:0008270; GO:0032553 26048 XM_044322338.1 19 0 60 36 3 NA NA NA NA NA NA 26049 XM_029329082.2 738 693 461 876 754 Q3SZC1 9.21e-64 GrpE protein homolog 1, mitochondrial (Mt-GrpE#1) (mt-GrpE) Bos taurus (Bovine) protein folding [GO:0006457]; protein import into mitochondrial matrix [GO:0030150] GO:0000774; GO:0001405; GO:0005654; GO:0006457; GO:0030150; GO:0042803; GO:0051082; GO:0051087 26050 XM_029357998.2 50 0 31 181 103 NA NA NA NA NA NA 26051 XM_029343383.2 1455 833 611 641 376 P58197 3.47e-77 Transcription factor AP-2-alpha (AP2-alpha) (AP-2 transcription factor) (Activating enhancer-binding protein 2-alpha) (Activator protein 2) (AP-2) Rattus norvegicus (Rat) anatomical structure development [GO:0048856]; anterior neuropore closure [GO:0021506]; basement membrane organization [GO:0071711]; bone morphogenesis [GO:0060349]; cell population proliferation [GO:0008283]; cellular response to iron ion [GO:0071281]; cornea development in camera-type eye [GO:0061303]; embryonic body morphogenesis [GO:0010172]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic forelimb morphogenesis [GO:0035115]; embryonic pattern specification [GO:0009880]; epidermal growth factor receptor signaling pathway [GO:0007173]; epidermis morphogenesis [GO:0048730]; eyelid development in camera-type eye [GO:0061029]; face morphogenesis [GO:0060325]; fibroblast migration [GO:0010761]; forebrain neuron development [GO:0021884]; forelimb morphogenesis [GO:0035136]; inner ear morphogenesis [GO:0042472]; keratinocyte development [GO:0003334]; kidney development [GO:0001822]; lens induction in camera-type eye [GO:0060235]; lens morphogenesis in camera-type eye [GO:0002089]; metanephric nephron development [GO:0072210]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of transcription by competitive promoter binding [GO:0010944]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; neural crest cell development [GO:0014032]; neural tube closure [GO:0001843]; neuron apoptotic process [GO:0051402]; oculomotor nerve formation [GO:0021623]; optic cup structural organization [GO:0003409]; optic vesicle morphogenesis [GO:0003404]; outflow tract morphogenesis [GO:0003151]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of tooth mineralization [GO:0070172]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; regulation of DNA-templated transcription [GO:0006355]; regulation of neuron differentiation [GO:0045664]; regulation of transcription by RNA polymerase II [GO:0006357]; response to lipopolysaccharide [GO:0032496]; response to water deprivation [GO:0009414]; retina layer formation [GO:0010842]; roof of mouth development [GO:0060021]; Schwann cell development [GO:0014044]; sensory organ development [GO:0007423]; sensory perception of sound [GO:0007605]; skeletal system morphogenesis [GO:0048705]; skin development [GO:0043588]; sympathetic nervous system development [GO:0048485]; transcription by RNA polymerase II [GO:0006366]; trigeminal nerve development [GO:0021559] GO:0000122; GO:0000976; GO:0000977; GO:0000978; GO:0000981; GO:0000987; GO:0001227; GO:0001228; GO:0001822; GO:0001843; GO:0002089; GO:0003151; GO:0003334; GO:0003404; GO:0003409; GO:0003677; GO:0003682; GO:0003700; GO:0003713; GO:0003714; GO:0005634; GO:0005905; GO:0006355; GO:0006357; GO:0006366; GO:0007173; GO:0007399; GO:0007423; GO:0007605; GO:0008283; GO:0008285; GO:0009414; GO:0009880; GO:0010172; GO:0010628; GO:0010761; GO:0010763; GO:0010842; GO:0010944; GO:0014032; GO:0014044; GO:0021506; GO:0021559; GO:0021623; GO:0021884; GO:0030335; GO:0030501; GO:0032496; GO:0035115; GO:0035136; GO:0042059; GO:0042127; GO:0042472; GO:0042802; GO:0043066; GO:0043524; GO:0043525; GO:0043565; GO:0043588; GO:0045595; GO:0045664; GO:0045892; GO:0045893; GO:0045944; GO:0048485; GO:0048596; GO:0048701; GO:0048705; GO:0048730; GO:0048856; GO:0051402; GO:0060021; GO:0060235; GO:0060325; GO:0060349; GO:0061029; GO:0061303; GO:0070172; GO:0071281; GO:0071711; GO:0072210; GO:0140536; GO:1990837; GO:2000378 26052 XM_044323823.1 0 0 7 13 0 Q4LDE5 1.57e-170 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 26053 XM_044323823.1 0 0 7 13 0 Q4LDE5 2.17e-168 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 26054 XM_044323823.1 0 0 7 13 0 Q4LDE5 4.49e-165 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 26055 XM_044323823.1 0 0 7 13 0 Q4LDE5 1.12e-163 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 26056 XM_044323823.1 0 0 7 13 0 Q4LDE5 2.21e-138 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 26057 XM_029345853.2 997 714 637 1394 1548 Q80V70 6.86e-59 Multiple epidermal growth factor-like domains protein 6 (Multiple EGF-like domains protein 6) (Epidermal growth factor-like protein 3) (EGF-like protein 3) Mus musculus (Mouse) NA GO:0005509; GO:0005576; GO:0062023 26058 XM_029345853.2 997 714 637 1394 1548 Q80V70 1.23e-37 Multiple epidermal growth factor-like domains protein 6 (Multiple EGF-like domains protein 6) (Epidermal growth factor-like protein 3) (EGF-like protein 3) Mus musculus (Mouse) NA GO:0005509; GO:0005576; GO:0062023 26059 XM_029345853.2 997 714 637 1394 1548 Q80V70 3.68e-37 Multiple epidermal growth factor-like domains protein 6 (Multiple EGF-like domains protein 6) (Epidermal growth factor-like protein 3) (EGF-like protein 3) Mus musculus (Mouse) NA GO:0005509; GO:0005576; GO:0062023 26060 XM_029341199.2 163 24 157 269 146 Q91175 7.43e-43 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (MAR1) Oryzias latipes (Japanese rice fish) (Japanese killifish) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of vasoconstriction [GO:0045907] GO:0001996; GO:0004930; GO:0004937; GO:0005886; GO:0007200; GO:0007204; GO:0007267; GO:0043410; GO:0045907; GO:0071880 26061 XM_029337199.2 3258 5784 1473 3449 2331 Q6PJ21 1.54e-33 SPRY domain-containing SOCS box protein 3 (SSB-3) Homo sapiens (Human) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567] GO:0005829; GO:0016567; GO:0019005; GO:0043161 26062 XM_029345195.2 1073 674 503 653 886 Q9DF58 0 Integrin-linked protein kinase (EC 2.7.11.1) (59 kDa serine/threonine-protein kinase) (Beta-integrin-linked kinase) (ILK-1) (ILK-2) (p59ILK) Gallus gallus (Chicken) branching involved in ureteric bud morphogenesis [GO:0001658]; cell projection organization [GO:0030030]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; fibroblast migration [GO:0010761]; integrin-mediated signaling pathway [GO:0007229]; myelination in peripheral nervous system [GO:0022011]; negative regulation of neural precursor cell proliferation [GO:2000178]; nerve development [GO:0021675]; neural precursor cell proliferation [GO:0061351]; outflow tract morphogenesis [GO:0003151]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein kinase B signaling [GO:0043491]; signal transduction [GO:0007165]; substrate adhesion-dependent cell spreading [GO:0034446]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0001658; GO:0001934; GO:0003151; GO:0004672; GO:0004674; GO:0005524; GO:0005654; GO:0005737; GO:0005886; GO:0005925; GO:0007165; GO:0007229; GO:0008284; GO:0010761; GO:0018105; GO:0019901; GO:0021675; GO:0022011; GO:0030017; GO:0030027; GO:0030030; GO:0030513; GO:0033209; GO:0034446; GO:0043491; GO:0045197; GO:0045669; GO:0045893; GO:0061351; GO:0090263; GO:1900026; GO:1901224; GO:2000178 26063 XM_029329210.2 21 5 3 15 43 NA NA NA NA NA NA 26064 XM_044327525.1 1067 735 376 1289 553 Q8BV79 0 TPR and ankyrin repeat-containing protein 1 (Lupus brain antigen 1) Mus musculus (Mouse) NA NA 26065 XM_044327525.1 1067 735 376 1289 553 Q8BV79 0 TPR and ankyrin repeat-containing protein 1 (Lupus brain antigen 1) Mus musculus (Mouse) NA NA 26066 XM_044326230.1 162 57 152 95 231 NA NA NA NA NA NA 26067 XM_029337246.2 462 306 286 651 360 NA NA NA NA NA NA 26068 XM_044327765.1 792 1747 307 507 938 NA NA NA NA NA NA 26069 XM_029349423.2 0 0 56 0 0 Q14CM0 3.49e-84 FERM and PDZ domain-containing protein 4 (PDZ domain-containing protein 10) (PSD-95-interacting regulator of spine morphogenesis) (Preso) Homo sapiens (Human) positive regulation of synapse structural plasticity [GO:0051835] GO:0005546; GO:0005856; GO:0032991; GO:0043197; GO:0051835 26070 XM_029349423.2 0 0 56 0 0 Q14CM0 3.49e-84 FERM and PDZ domain-containing protein 4 (PDZ domain-containing protein 10) (PSD-95-interacting regulator of spine morphogenesis) (Preso) Homo sapiens (Human) positive regulation of synapse structural plasticity [GO:0051835] GO:0005546; GO:0005856; GO:0032991; GO:0043197; GO:0051835 26071 XM_044310179.1 11 18 16 0 3 Q05AS9 4.49e-158 Protein transport protein Sec23A (SEC23-related protein A) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) COPII-coated vesicle cargo loading [GO:0090110]; intracellular protein transport [GO:0006886] GO:0005789; GO:0005829; GO:0006886; GO:0008270; GO:0019898; GO:0030127; GO:0070971; GO:0090110 26072 XM_044311230.1 7 0 3 0 76 NA NA NA NA NA NA 26073 XR_006397529.1 3072 2361 2056 4054 3865 Q8YV57 1.86e-28 Uncharacterized WD repeat-containing protein all2124 Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576) proteolysis [GO:0006508] GO:0004197; GO:0006508 26074 XR_006397529.1 3072 2361 2056 4054 3865 Q8YV57 1.86e-28 Uncharacterized WD repeat-containing protein all2124 Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576) proteolysis [GO:0006508] GO:0004197; GO:0006508 26075 XM_044319766.1 2548 2457 1881 2709 2616 P20456 1.79e-92 Inositol monophosphatase 1 (IMP 1) (IMPase 1) (EC 3.1.3.25) (D-galactose 1-phosphate phosphatase) (EC 3.1.3.94) (Inositol-1(or 4)-monophosphatase 1) (Lithium-sensitive myo-inositol monophosphatase A1) Bos taurus (Bovine) inositol biosynthetic process [GO:0006021]; inositol metabolic process [GO:0006020]; inositol phosphate dephosphorylation [GO:0046855]; phosphatidylinositol phosphate biosynthetic process [GO:0046854]; signal transduction [GO:0007165] GO:0000287; GO:0005737; GO:0006020; GO:0006021; GO:0007165; GO:0008934; GO:0030145; GO:0031403; GO:0046854; GO:0046855; GO:0052832; GO:0052833; GO:0052834 26076 XR_003824872.2 0 0 1 1 6 NA NA NA NA NA NA 26077 XM_029340282.2 32 9 0 46 3 Q5RA50 4.95e-26 Protein FAM124A Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA NA 26078 XM_044328639.1 0 0 0 7 2 NA NA NA NA NA NA 26079 XM_029346856.2 984 541 1125 587 2003 NA NA NA NA NA NA 26080 XM_029345808.2 492 251 372 251 569 Q7ZY86 1.63e-104 Transmembrane protein 168 Xenopus laevis (African clawed frog) NA GO:0017080; GO:0031965 26081 XM_029342630.2 334 99 0 191 233 Q58A42 4.78e-73 Protein DD3-3 Dictyostelium discoideum (Social amoeba) NA GO:0016020 26082 XR_006393650.1 51 444 732 274 193 NA NA NA NA NA NA 26083 XM_044324430.1 19 16 0 9 16 NA NA NA NA NA NA 26084 XM_029327348.2 0 4 10 24 5 NA NA NA NA NA NA 26085 XM_029348027.2 0 149 136 103 258 P36876 0 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform (PP2A subunit B isoform B55-alpha) (PP2A subunit B isoform BRA) (PP2A subunit B isoform PR55-alpha) (PP2A subunit B isoform R2-alpha) (PP2A subunit B isoform alpha) Rattus norvegicus (Rat) protein dephosphorylation [GO:0006470]; response to morphine [GO:0043278] GO:0000159; GO:0005829; GO:0006470; GO:0019888; GO:0043278; GO:0044877; GO:0045202; GO:0048156; GO:0051721; GO:0098978 26086 XR_006394474.1 135 0 18 52 108 NA NA NA NA NA NA 26087 XM_029351703.2 34 0 41 71 35 Q9H089 0 Large subunit GTPase 1 homolog (hLsg1) (EC 3.6.1.-) Homo sapiens (Human) nuclear export [GO:0051168]; protein transport [GO:0015031]; ribosomal subunit export from nucleus [GO:0000054] GO:0000054; GO:0003924; GO:0005525; GO:0005654; GO:0005783; GO:0005829; GO:0015030; GO:0015031; GO:0016020; GO:0016604; GO:0051168 26088 XR_006395302.1 585 240 66 30 1338 NA NA NA NA NA NA 26089 XM_029338741.2 2034 2768 1676 1838 1582 P05198 1.87e-148 Eukaryotic translation initiation factor 2 subunit 1 (Eukaryotic translation initiation factor 2 subunit alpha) (eIF-2-alpha) (eIF-2A) (eIF-2alpha) Homo sapiens (Human) aging [GO:0007568]; cellular response to amino acid starvation [GO:0034198]; cellular response to heat [GO:0034605]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; negative regulation of guanyl-nucleotide exchange factor activity [GO:1905098]; negative regulation of translational initiation in response to stress [GO:0032057]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of neuron death [GO:1901216]; positive regulation of type B pancreatic cell apoptotic process [GO:2000676]; protein autophosphorylation [GO:0046777]; regulation of translational initiation in response to stress [GO:0043558]; response to endoplasmic reticulum stress [GO:0034976]; response to manganese-induced endoplasmic reticulum stress [GO:1990737]; stress granule assembly [GO:0034063] GO:0003723; GO:0003743; GO:0005634; GO:0005829; GO:0005844; GO:0005850; GO:0005851; GO:0007568; GO:0010494; GO:0016020; GO:0032057; GO:0033290; GO:0034063; GO:0034198; GO:0034599; GO:0034605; GO:0034644; GO:0034976; GO:0036499; GO:0043022; GO:0043558; GO:0043614; GO:0044207; GO:0045202; GO:0046777; GO:0070062; GO:0097451; GO:1901216; GO:1905098; GO:1990737; GO:2000676 26090 XM_029354576.2 0 0 0 9 7 NA NA NA NA NA NA 26091 XM_044314808.1 0 0 2 0 42 NA NA NA NA NA NA 26092 XM_044321046.1 10 10 0 246 3 NA NA NA NA NA NA 26093 XR_006394119.1 337 292 249 264 371 NA NA NA NA NA NA 26094 XM_029358665.2 4 23 0 9 4 NA NA NA NA NA NA 26095 XM_044317145.1 0 0 12 14 3 NA NA NA NA NA NA 26096 XM_044309832.1 0 0 6 159 0 Q29RU2 1.52e-35 Oncoprotein-induced transcript 3 protein Bos taurus (Bovine) NA GO:0005509; GO:0005635 26097 XM_044312132.1 1 0 0 1 34 NA NA NA NA NA NA 26098 XM_029356210.2 2582 3186 1461 2216 1977 Q9CR41 4.46e-32 Huntingtin-interacting protein K (Huntingtin yeast partner K) Mus musculus (Mouse) negative regulation of apoptotic process [GO:0043066]; protein stabilization [GO:0050821] GO:0005634; GO:0005654; GO:0005737; GO:0015630; GO:0032991; GO:0043066; GO:0044183; GO:0047485; GO:0050821 26099 XR_006393404.1 6 0 0 0 0 NA NA NA NA NA NA 26100 XM_044307194.1 92 49 0 0 0 NA NA NA NA NA NA 26101 XM_044317563.1 0 0 1 0 10 Q8BM14 1.58e-70 Lipase member K (EC 3.1.1.-) (Lipase-like abhydrolase domain-containing protein 2) Mus musculus (Mouse) lipid catabolic process [GO:0016042] GO:0005576; GO:0016042; GO:0016788; GO:0043231 26102 XM_029332746.2 1685 1072 885 1147 1387 Q5ZLW3 0 Dymeclin Gallus gallus (Chicken) Golgi organization [GO:0007030] GO:0005794; GO:0007030 26103 XM_044316071.1 271 63 135 292 106 Q66GV0 8.32e-50 Protein Mpv17 Xenopus laevis (African clawed frog) NA GO:0005743 26104 XR_006396297.1 57 41 10 47 65 NA NA NA NA NA NA 26105 XM_029356107.2 2214 1054 807 1134 1284 NA NA NA NA NA NA 26106 XM_044318788.1 49 0 88 0 455 NA NA NA NA NA NA 26107 XM_044322149.1 25 10 12 16 27 A1L2Q8 4.6e-62 Pyrroline-5-carboxylate reductase 3 (P5C reductase 3) (P5CR 3) (EC 1.5.1.2) (Pyrroline-5-carboxylate reductase-like protein) Xenopus laevis (African clawed frog) L-proline biosynthetic process [GO:0055129] GO:0004735; GO:0005829; GO:0055129 26108 XR_006394085.1 50 8 27 88 90 NA NA NA NA NA NA 26109 XM_044312502.1 0 0 38 2 157 P84239 9.89e-90 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 26110 XM_029344578.2 285 154 180 226 215 Q9HAC7 5.92e-165 Succinate--hydroxymethylglutarate CoA-transferase (EC 2.8.3.13) (Dermal papilla-derived protein 13) (SuccinylCoA:glutarate-CoA transferase) Homo sapiens (Human) NA GO:0005739; GO:0047369 26111 XM_044315921.1 8 0 1 0 1 NA NA NA NA NA NA 26112 XM_029338878.2 288 255 148 298 213 A7RF00 4.37e-135 Methylthioribose-1-phosphate isomerase (M1Pi) (MTR-1-P isomerase) (EC 5.3.1.23) (S-methyl-5-thioribose-1-phosphate isomerase) (Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein) Nematostella vectensis (Starlet sea anemone) L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284] GO:0005634; GO:0005737; GO:0019284; GO:0019509; GO:0046523 26113 XM_044319299.1 9 22 0 17 32 NA NA NA NA NA NA 26114 XM_029356638.2 2749 1771 1005 1590 1867 NA NA NA NA NA NA 26115 XM_029356405.2 317 226 247 206 374 Q9NRM2 2.24e-120 Zinc finger protein 277 (Nuclear receptor-interacting factor 4) Homo sapiens (Human) cellular response to hydrogen peroxide [GO:0070301]; regulation of cellular senescence [GO:2000772] GO:0000978; GO:0005634; GO:0046872; GO:0070301; GO:2000772 26116 XM_044313821.1 13 0 0 0 4 NA NA NA NA NA NA 26117 XR_006394662.1 173 109 147 171 384 NA NA NA NA NA NA 26118 XM_044318775.1 925 516 480 843 944 Q8R0G9 0 Nuclear pore complex protein Nup133 (133 kDa nucleoporin) (Nucleoporin Nup133) Mus musculus (Mouse) mRNA export from nucleus [GO:0006406]; nephron development [GO:0072006]; neural tube development [GO:0021915]; neurogenesis [GO:0022008]; nuclear pore organization [GO:0006999]; nucleocytoplasmic transport [GO:0006913]; paraxial mesoderm development [GO:0048339]; poly(A)+ mRNA export from nucleus [GO:0016973]; protein import into nucleus [GO:0006606]; somite development [GO:0061053]; transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000972] GO:0000776; GO:0000940; GO:0000972; GO:0005635; GO:0005643; GO:0006406; GO:0006606; GO:0006913; GO:0006999; GO:0016973; GO:0017056; GO:0021915; GO:0022008; GO:0031080; GO:0031965; GO:0048339; GO:0061053; GO:0072006 26119 XR_003826574.2 0 0 13 4 77 NA NA NA NA NA NA 26120 XM_029333317.2 10 186 24 116 221 Q12923 3.97e-57 Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1) (PTP-BAS) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (Protein-tyrosine phosphatase PTPL1) Homo sapiens (Human) cellular response to toxic substance [GO:0097237]; negative regulation of excitatory synapse assembly [GO:1904890]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066] GO:0001650; GO:0001933; GO:0004725; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0006470; GO:0014066; GO:0030027; GO:0035335; GO:0036312; GO:0043005; GO:0044297; GO:0070062; GO:0097237; GO:1904890 26121 XM_029333317.2 10 186 24 116 221 Q12923 2.24e-28 Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1) (PTP-BAS) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (Protein-tyrosine phosphatase PTPL1) Homo sapiens (Human) cellular response to toxic substance [GO:0097237]; negative regulation of excitatory synapse assembly [GO:1904890]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066] GO:0001650; GO:0001933; GO:0004725; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0006470; GO:0014066; GO:0030027; GO:0035335; GO:0036312; GO:0043005; GO:0044297; GO:0070062; GO:0097237; GO:1904890 26122 XM_044327541.1 29 60 94 0 226 NA NA NA NA NA NA 26123 XM_029344446.2 84 107 97 21 135 Q8WP23 1.3e-21 Protein boule-like Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) cell differentiation [GO:0030154]; regulation of translation [GO:0006417]; spermatogenesis [GO:0007283] GO:0003723; GO:0005737; GO:0006417; GO:0007283; GO:0030154 26124 XM_029334062.2 259 197 121 111 220 NA NA NA NA NA NA 26125 XM_044309263.1 19 18 33 23 35 NA NA NA NA NA NA 26126 XR_006394534.1 422 497 67 163 119 NA NA NA NA NA NA 26127 XR_006392636.1 0 3 0 0 6 NA NA NA NA NA NA 26128 XM_029342206.2 393 247 356 192 300 D3Z8N4 2.6e-123 Kelch-like protein 20 Rattus norvegicus (Rat) Golgi to endosome transport [GO:0006895]; negative regulation of apoptotic process [GO:0043066]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K33-linked ubiquitination [GO:1990390]; protein transport [GO:0015031]; protein ubiquitination [GO:0016567] GO:0003779; GO:0004842; GO:0005737; GO:0005802; GO:0005829; GO:0006895; GO:0015031; GO:0016567; GO:0016605; GO:0019964; GO:0030424; GO:0030425; GO:0031463; GO:0043066; GO:0043161; GO:0048471; GO:1990390 26129 XR_006397151.1 697 278 227 917 584 NA NA NA NA NA NA 26130 XM_044314413.1 0 0 47 0 110 NA NA NA NA NA NA 26131 XM_029342281.2 1579 852 272 1105 782 NA NA NA NA NA NA 26132 XR_003822854.2 1 20 82 5 9 NA NA NA NA NA NA 26133 XM_044322829.1 3306 5339 2000 3472 790 G1TFM5 2.61e-132 NA NA NA NA 26134 XM_044328327.1 5 8 14 8 10 NA NA NA NA NA NA 26135 XM_044307507.1 0 0 7 6 6 NA NA NA NA NA NA 26136 XM_044320036.1 0 0 15 0 2 NA NA NA NA NA NA 26137 XM_029325721.2 2 27 37 8 3 NA NA NA NA NA NA 26138 XR_006391485.1 179 57 149 91 148 NA NA NA NA NA NA 26139 XM_044319332.1 0 0 0 0 10 NA NA NA NA NA NA 26140 XR_006398007.1 111 38 8 76 42 NA NA NA NA NA NA 26141 XR_006394134.1 49 24 0 35 0 NA NA NA NA NA NA 26142 XM_044317622.1 17 20 4 43 144 NA NA NA NA NA NA 26143 XM_029357110.2 12 51 18 7 15 O17185 8.01e-26 Two pore potassium channel protein sup-9 (Suppressor of unc-93 protein 9) (n2P38) Caenorhabditis elegans potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of muscle contraction [GO:0006937]; stabilization of membrane potential [GO:0030322] GO:0005267; GO:0005886; GO:0006813; GO:0006937; GO:0015271; GO:0022841; GO:0030322; GO:0036195; GO:0055120; GO:0071805 26144 XM_044324372.1 30 34 28 31 31 NA NA NA NA NA NA 26145 XM_044326582.1 611 398 599 687 539 Q21106 0 DDB1- and CUL4-associated factor homolog 1 Caenorhabditis elegans protein ubiquitination [GO:0016567] GO:0005634; GO:0016567; GO:0080008 26146 XM_044314919.1 0 0 2 0 46 NA NA NA NA NA NA 26147 XM_044311523.1 0 100 0 269 96 Q9VBW3 1.74e-77 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 26148 XR_006392864.1 5 6 57 66 45 NA NA NA NA NA NA 26149 XM_044321184.1 2048 1210 548 1549 1046 Q5R8Z8 5.91e-132 Ras-related protein Rab-14 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) defense response to bacterium [GO:0042742]; endocytic recycling [GO:0032456]; fibroblast growth factor receptor signaling pathway [GO:0008543]; Golgi to endosome transport [GO:0006895]; phagosome maturation [GO:0090382]; protein transport [GO:0015031]; regulation of embryonic development [GO:0045995]; regulation of protein localization [GO:0032880] GO:0000139; GO:0003924; GO:0005525; GO:0005802; GO:0005829; GO:0006895; GO:0008543; GO:0015031; GO:0019003; GO:0031901; GO:0032456; GO:0032880; GO:0042742; GO:0045335; GO:0045995; GO:0055037; GO:0090382 26150 XM_029349183.2 0 0 0 0 69 NA NA NA NA NA NA 26151 XM_029347108.2 0 0 20 0 0 NA NA NA NA NA NA 26152 XM_044322352.1 0 8 0 0 0 P06845 3.73e-22 Tyrosinase (EC 1.14.18.1) (Monophenol monooxygenase) Streptomyces glaucescens melanin biosynthetic process [GO:0042438] GO:0004503; GO:0042438; GO:0046872 26153 XM_029333551.2 5 16 6 23 19 NA NA NA NA NA NA 26154 XM_044310606.1 1552 1575 1168 2130 1634 NA NA NA NA NA NA 26155 XM_044317928.1 2065 993 1087 5129 5414 Q5QNI2 2.27e-29 Sodium/calcium exchanger NCL1 (Na(+)/Ca(2+)-exchange protein NCL1) (OsEFCAX1) (Protein NCX-like 1) (OsNCL1) Oryza sativa subsp. japonica (Rice) calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; sodium ion transport [GO:0006814] GO:0005509; GO:0005774; GO:0005886; GO:0006814; GO:0006874; GO:0015369; GO:0070588 26156 XM_029344724.2 7 0 0 0 15 Q5R2J4 3.97e-75 Protein APCDD1 (Adenomatosis polyposis coli down-regulated 1 protein homolog) (PsAPCDD1) Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis) negative regulation of Wnt signaling pathway [GO:0030178]; Wnt signaling pathway [GO:0016055] GO:0005615; GO:0005886; GO:0016055; GO:0017147; GO:0030178 26157 XM_029347047.2 679 515 332 475 409 NA NA NA NA NA NA 26158 XM_044317415.1 2734 1978 1640 3241 3492 Q9BYB0 6.16e-99 SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) Homo sapiens (Human) adult behavior [GO:0030534]; AMPA glutamate receptor clustering [GO:0097113]; brain morphogenesis [GO:0048854]; dendritic spine morphogenesis [GO:0060997]; guanylate kinase-associated protein clustering [GO:0097117]; learning [GO:0007612]; MAPK cascade [GO:0000165]; memory [GO:0007613]; negative regulation of actin filament bundle assembly [GO:0032232]; negative regulation of cell volume [GO:0045794]; NMDA glutamate receptor clustering [GO:0097114]; positive regulation of AMPA receptor activity [GO:2000969]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of glutamate receptor signaling pathway [GO:1900451]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of synapse structural plasticity [GO:0051835]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density assembly [GO:0097107]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of long-term synaptic depression [GO:1900452]; regulation of long-term synaptic potentiation [GO:1900271]; social behavior [GO:0035176]; striatal medium spiny neuron differentiation [GO:0021773]; synapse assembly [GO:0007416]; vocal learning [GO:0042297]; vocalization behavior [GO:0071625] GO:0000165; GO:0003779; GO:0005829; GO:0007416; GO:0007612; GO:0007613; GO:0008022; GO:0008270; GO:0014069; GO:0017124; GO:0021773; GO:0030160; GO:0030534; GO:0031234; GO:0032232; GO:0035176; GO:0035255; GO:0042297; GO:0043005; GO:0043197; GO:0043621; GO:0044309; GO:0045794; GO:0048170; GO:0048854; GO:0051835; GO:0051968; GO:0060170; GO:0060997; GO:0060999; GO:0061001; GO:0071625; GO:0097107; GO:0097110; GO:0097113; GO:0097114; GO:0097117; GO:1900271; GO:1900273; GO:1900451; GO:1900452; GO:2000463; GO:2000969 26159 XM_044317415.1 2734 1978 1640 3241 3492 Q9BYB0 3.79e-32 SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) Homo sapiens (Human) adult behavior [GO:0030534]; AMPA glutamate receptor clustering [GO:0097113]; brain morphogenesis [GO:0048854]; dendritic spine morphogenesis [GO:0060997]; guanylate kinase-associated protein clustering [GO:0097117]; learning [GO:0007612]; MAPK cascade [GO:0000165]; memory [GO:0007613]; negative regulation of actin filament bundle assembly [GO:0032232]; negative regulation of cell volume [GO:0045794]; NMDA glutamate receptor clustering [GO:0097114]; positive regulation of AMPA receptor activity [GO:2000969]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of glutamate receptor signaling pathway [GO:1900451]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of synapse structural plasticity [GO:0051835]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density assembly [GO:0097107]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of long-term synaptic depression [GO:1900452]; regulation of long-term synaptic potentiation [GO:1900271]; social behavior [GO:0035176]; striatal medium spiny neuron differentiation [GO:0021773]; synapse assembly [GO:0007416]; vocal learning [GO:0042297]; vocalization behavior [GO:0071625] GO:0000165; GO:0003779; GO:0005829; GO:0007416; GO:0007612; GO:0007613; GO:0008022; GO:0008270; GO:0014069; GO:0017124; GO:0021773; GO:0030160; GO:0030534; GO:0031234; GO:0032232; GO:0035176; GO:0035255; GO:0042297; GO:0043005; GO:0043197; GO:0043621; GO:0044309; GO:0045794; GO:0048170; GO:0048854; GO:0051835; GO:0051968; GO:0060170; GO:0060997; GO:0060999; GO:0061001; GO:0071625; GO:0097107; GO:0097110; GO:0097113; GO:0097114; GO:0097117; GO:1900271; GO:1900273; GO:1900451; GO:1900452; GO:2000463; GO:2000969 26160 XM_029334419.2 19 5 14 37 0 Q91981 1.67e-32 Homeobox protein OTX2 (zOTX2) (Orthodenticle homolog 2) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to alcohol [GO:0097306]; cerebellum development [GO:0021549]; hindbrain development [GO:0030902]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; regulation of transcription by RNA polymerase II [GO:0006357]; retinal pigment epithelium development [GO:0003406] GO:0000978; GO:0000981; GO:0003406; GO:0005634; GO:0006357; GO:0021549; GO:0030901; GO:0030902; GO:0030917; GO:0097306 26161 XM_029332376.2 0 52 227 2119 3611 Q0P8I7 3.87e-77 GDP-D-glycero-alpha-D-manno-heptose dehydrogenase (EC 1.1.98.-) Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) capsule polysaccharide biosynthetic process [GO:0045227]; protein homotetramerization [GO:0051289] GO:0003978; GO:0016491; GO:0019003; GO:0042802; GO:0045227; GO:0051289; GO:0070404 26162 XM_029331922.2 181 206 0 101 78 Q5F362 8.99e-105 Cell cycle control protein 50A (P4-ATPase flippase complex beta subunit TMEM30A) (Transmembrane protein 30A) Gallus gallus (Chicken) phospholipid translocation [GO:0045332] GO:0001750; GO:0001917; GO:0005783; GO:0005794; GO:0005886; GO:0016324; GO:0030658; GO:0045332; GO:1990531 26163 XM_029324895.2 113 126 79 152 24 NA NA NA NA NA NA 26164 XM_044324214.1 103 149 100 166 153 NA NA NA NA NA NA 26165 XR_006394537.1 76 19 36 94 82 NA NA NA NA NA NA 26166 XM_044307146.1 4 0 172 178 0 Q9BHM6 2.71e-32 Octopine dehydrogenase (OcDH) (EC 1.5.1.11) Pecten maximus (King scallop) (Pilgrim's clam) NA GO:0000166; GO:0047830 26167 XM_044324951.1 0 0 0 61 292 NA NA NA NA NA NA 26168 XM_029352443.2 18 0 56 0 0 Q9Y672 6.68e-117 Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase (EC 2.4.1.267) (Asparagine-linked glycosylation protein 6 homolog) (Dol-P-Glc:Man(9)GlcNAc(2)-PP-Dol alpha-1,3-glucosyltransferase) (Dolichyl-P-Glc:Man9GlcNAc2-PP-dolichyl glucosyltransferase) Homo sapiens (Human) dolichol-linked oligosaccharide biosynthetic process [GO:0006488]; oligosaccharide-lipid intermediate biosynthetic process [GO:0006490]; protein N-linked glycosylation [GO:0006487] GO:0004583; GO:0005789; GO:0006487; GO:0006488; GO:0006490; GO:0016020; GO:0042281; GO:0046527 26169 XM_029349110.2 291 154 130 201 269 Q5R9K8 1.27e-53 ADP-ribosylation factor-like protein 2-binding protein (ARF-like 2-binding protein) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) maintenance of protein location in nucleus [GO:0051457]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531] GO:0003713; GO:0005654; GO:0005758; GO:0005813; GO:0005819; GO:0005829; GO:0005929; GO:0030496; GO:0042531; GO:0051457 26170 XM_044317418.1 97 379 185 236 146 O93430 2.9e-68 Glycine receptor subunit alphaZ1 Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to amino acid stimulus [GO:0071230]; cellular response to ethanol [GO:0071361]; cellular response to zinc ion [GO:0071294]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; nervous system process [GO:0050877]; neuropeptide signaling pathway [GO:0007218]; regulation of membrane potential [GO:0042391]; regulation of neuron differentiation [GO:0045664]; response to amino acid [GO:0043200]; signal transduction [GO:0007165]; synaptic transmission, glycinergic [GO:0060012] GO:0004888; GO:0005231; GO:0005886; GO:0006811; GO:0007165; GO:0007218; GO:0007268; GO:0007417; GO:0008270; GO:0016594; GO:0016933; GO:0016934; GO:0030425; GO:0030594; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0043200; GO:0043204; GO:0045202; GO:0045211; GO:0045664; GO:0050877; GO:0060012; GO:0071230; GO:0071294; GO:0071361; GO:1902476; GO:1904315 26171 XM_029335420.2 64 57 5 39 21 NA NA NA NA NA NA 26172 XM_044307051.1 0 0 0 0 9 NA NA NA NA NA NA 26173 XM_029333130.2 23 3 48 5 65 NA NA NA NA NA NA 26174 XM_029351999.2 2045 1718 1422 1869 1831 P08003 0 Protein disulfide-isomerase A4 (EC 5.3.4.1) (Endoplasmic reticulum resident protein 72) (ER protein 72) (ERp-72) (ERp72) Mus musculus (Mouse) chaperone-mediated protein folding [GO:0061077]; positive regulation of protein folding [GO:1903334]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976] GO:0003756; GO:0005615; GO:0005783; GO:0005788; GO:0005790; GO:0006457; GO:0009986; GO:0015035; GO:0034663; GO:0034976; GO:0042470; GO:0061077; GO:1903334 26175 XM_029351999.2 2045 1718 1422 1869 1831 P08003 2.29e-28 Protein disulfide-isomerase A4 (EC 5.3.4.1) (Endoplasmic reticulum resident protein 72) (ER protein 72) (ERp-72) (ERp72) Mus musculus (Mouse) chaperone-mediated protein folding [GO:0061077]; positive regulation of protein folding [GO:1903334]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976] GO:0003756; GO:0005615; GO:0005783; GO:0005788; GO:0005790; GO:0006457; GO:0009986; GO:0015035; GO:0034663; GO:0034976; GO:0042470; GO:0061077; GO:1903334 26176 XR_006394458.1 0 0 0 0 23 P17971 7.94e-70 Potassium voltage-gated channel protein Shal (Shaker cognate l) (Shal2) Drosophila melanogaster (Fruit fly) associative learning [GO:0008306]; chemical synaptic transmission [GO:0007268]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005250; GO:0005886; GO:0006813; GO:0007268; GO:0008076; GO:0008306; GO:0016020; GO:0030425; GO:0034765; GO:0043204; GO:0045202; GO:0051260; GO:0071805 26177 XR_006394458.1 0 0 0 0 23 P17971 7.94e-70 Potassium voltage-gated channel protein Shal (Shaker cognate l) (Shal2) Drosophila melanogaster (Fruit fly) associative learning [GO:0008306]; chemical synaptic transmission [GO:0007268]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005250; GO:0005886; GO:0006813; GO:0007268; GO:0008076; GO:0008306; GO:0016020; GO:0030425; GO:0034765; GO:0043204; GO:0045202; GO:0051260; GO:0071805 26178 XR_006394458.1 0 0 0 0 23 P17971 7.94e-70 Potassium voltage-gated channel protein Shal (Shaker cognate l) (Shal2) Drosophila melanogaster (Fruit fly) associative learning [GO:0008306]; chemical synaptic transmission [GO:0007268]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005250; GO:0005886; GO:0006813; GO:0007268; GO:0008076; GO:0008306; GO:0016020; GO:0030425; GO:0034765; GO:0043204; GO:0045202; GO:0051260; GO:0071805 26179 XR_006394458.1 0 0 0 0 23 P17971 7.94e-70 Potassium voltage-gated channel protein Shal (Shaker cognate l) (Shal2) Drosophila melanogaster (Fruit fly) associative learning [GO:0008306]; chemical synaptic transmission [GO:0007268]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005250; GO:0005886; GO:0006813; GO:0007268; GO:0008076; GO:0008306; GO:0016020; GO:0030425; GO:0034765; GO:0043204; GO:0045202; GO:0051260; GO:0071805 26180 XM_044308171.1 107 195 202 103 56 NA NA NA NA NA NA 26181 XM_029347983.2 110 68 14 38 128 NA NA NA NA NA NA 26182 XM_029327223.2 40 45 43 0 27 Q9D8Y8 2.02e-89 Inhibitor of growth protein 5 Mus musculus (Mouse) apoptotic signaling pathway [GO:0097190]; DNA replication-dependent chromatin disassembly [GO:0140889]; fibroblast proliferation [GO:0048144]; histone H4-K12 acetylation [GO:0043983]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; histone modification [GO:0016570]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of growth [GO:0045926]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of DNA-templated transcription [GO:0045893]; protein acetylation [GO:0006473]; regulation of cell cycle [GO:0051726]; regulation of cell growth [GO:0001558]; regulation of developmental process [GO:0050793]; regulation of DNA biosynthetic process [GO:2000278]; regulation of DNA replication [GO:0006275]; regulation of DNA-templated transcription [GO:0006355]; regulation of hemopoiesis [GO:1903706] GO:0000123; GO:0001558; GO:0003682; GO:0005634; GO:0005654; GO:0006275; GO:0006355; GO:0006473; GO:0008285; GO:0016570; GO:0035064; GO:0043065; GO:0043981; GO:0043982; GO:0043983; GO:0045893; GO:0045926; GO:0046872; GO:0048144; GO:0048147; GO:0050793; GO:0051726; GO:0070776; GO:0097190; GO:0140889; GO:1903706; GO:2000278; GO:2001235 26183 XM_029347717.2 416 390 280 497 418 Q09143 3.99e-108 High affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (Ecotropic retroviral leukemia receptor) (Ecotropic retrovirus receptor) (ERR) (EcoR) (Solute carrier family 7 member 1) (System Y+ basic amino acid transporter) Mus musculus (Mouse) amino acid import across plasma membrane [GO:0089718]; amino acid transport [GO:0006865]; L-amino acid transport [GO:0015807]; L-arginine import across plasma membrane [GO:0097638]; L-arginine transmembrane transport [GO:1903826]; L-histidine import across plasma membrane [GO:1903810]; L-ornithine transmembrane transport [GO:1903352]; lysine transport [GO:0015819]; ornithine transport [GO:0015822]; positive regulation of T cell proliferation [GO:0042102]; regulation of TOR signaling [GO:0032006] GO:0000064; GO:0001618; GO:0005290; GO:0005886; GO:0006865; GO:0009925; GO:0015171; GO:0015174; GO:0015189; GO:0015807; GO:0015819; GO:0015822; GO:0016020; GO:0016323; GO:0016324; GO:0032006; GO:0032991; GO:0042102; GO:0061459; GO:0089718; GO:0097638; GO:1903352; GO:1903810; GO:1903826 26184 XR_006397331.1 19 0 1 18 69 NA NA NA NA NA NA 26185 XM_044319834.1 0 0 0 11 23 NA NA NA NA NA NA 26186 XM_044321157.1 13 11 1 0 4 NA NA NA NA NA NA 26187 XM_044312854.1 57 76 81 114 86 NA NA NA NA NA NA 26188 XM_044318760.1 7 52 21 11 8 Q76KP1 7.85e-61 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Homo sapiens (Human) NA GO:0008376; GO:0032580; GO:0033842 26189 XM_044318760.1 7 52 21 11 8 Q76KP1 4.9e-24 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Homo sapiens (Human) NA GO:0008376; GO:0032580; GO:0033842 26190 XR_006395640.1 21 94 88 73 148 NA NA NA NA NA NA 26191 XM_029334295.2 1964 1653 2073 2615 1736 NA NA NA NA NA NA 26192 XM_029353057.2 160 220 129 175 328 Q5SWK7 7.86e-43 RING finger protein 145 (EC 2.3.2.27) Mus musculus (Mouse) NA GO:0005783; GO:0005789; GO:0008270; GO:0012505; GO:0061630 26193 XM_029334352.2 0 0 4 6 6 NA NA NA NA NA NA 26194 XR_006397211.1 57 301 67 116 55 NA NA NA NA NA NA 26195 XM_044317077.1 33 2 12 14 14 P10079 4e-95 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 26196 XM_044317077.1 33 2 12 14 14 P10079 1.14e-93 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 26197 XM_044317077.1 33 2 12 14 14 P10079 1.75e-93 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 26198 XM_044317077.1 33 2 12 14 14 P10079 1.81e-84 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 26199 XM_044317077.1 33 2 12 14 14 P10079 1.76e-82 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 26200 XM_044317077.1 33 2 12 14 14 P10079 9.29e-78 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 26201 XM_044317077.1 33 2 12 14 14 P10079 3.48e-58 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 26202 XM_029332267.2 297 313 250 629 623 NA NA NA NA NA NA 26203 XM_029352440.2 805 630 520 781 845 Q9UIJ7 5.57e-85 GTP:AMP phosphotransferase AK3, mitochondrial (EC 2.7.4.10) (Adenylate kinase 3) (AK 3) (Adenylate kinase 3 alpha-like 1) Homo sapiens (Human) ADP biosynthetic process [GO:0006172]; AMP metabolic process [GO:0046033]; blood coagulation [GO:0007596]; GTP metabolic process [GO:0046039]; ITP metabolic process [GO:0046041]; nucleoside triphosphate biosynthetic process [GO:0009142]; phosphorylation [GO:0016310]; UTP metabolic process [GO:0046051] GO:0005524; GO:0005525; GO:0005737; GO:0005739; GO:0005759; GO:0006172; GO:0007596; GO:0009142; GO:0016310; GO:0046033; GO:0046039; GO:0046041; GO:0046051; GO:0046899 26204 XM_029338532.2 566 448 278 520 573 NA NA NA NA NA NA 26205 XM_029331567.2 0 70 127 97 259 NA NA NA NA NA NA 26206 XM_029341624.2 687 568 374 667 419 NA NA NA NA NA NA 26207 XM_044322470.1 2116 1962 150 75 67 O89110 6.49e-40 Caspase-8 (CASP-8) (EC 3.4.22.61) [Cleaved into: Caspase-8 subunit p18; Caspase-8 subunit p10] Mus musculus (Mouse) activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cardiac muscle tissue development [GO:0048738]; execution phase of apoptosis [GO:0097194]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; heart development [GO:0007507]; hepatocyte apoptotic process [GO:0097284]; macrophage differentiation [GO:0030225]; necroptotic process [GO:0070266]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of necroptotic process [GO:0060546]; neural tube formation [GO:0001841]; positive regulation of apoptotic process [GO:0043065]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of neuron death [GO:1901216]; positive regulation of proteolysis [GO:0045862]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; pyroptosis [GO:0070269]; regulation of apoptotic signaling pathway [GO:2001233]; regulation of cytokine production [GO:0001817]; regulation of innate immune response [GO:0045088]; regulation of thymocyte apoptotic process [GO:0070243]; response to ethanol [GO:0045471]; response to tumor necrosis factor [GO:0034612]; self proteolysis [GO:0097264]; TRAIL-activated apoptotic signaling pathway [GO:0036462] GO:0001525; GO:0001817; GO:0001841; GO:0004175; GO:0004197; GO:0005123; GO:0005164; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005829; GO:0005886; GO:0006508; GO:0006915; GO:0006919; GO:0007507; GO:0008233; GO:0008303; GO:0008625; GO:0016485; GO:0030225; GO:0030690; GO:0031264; GO:0031265; GO:0031625; GO:0032731; GO:0032991; GO:0034612; GO:0035877; GO:0036462; GO:0042802; GO:0043005; GO:0043065; GO:0043123; GO:0043124; GO:0044297; GO:0044877; GO:0045088; GO:0045121; GO:0045471; GO:0045651; GO:0045862; GO:0048738; GO:0051603; GO:0060546; GO:0070243; GO:0070266; GO:0070269; GO:0097110; GO:0097153; GO:0097190; GO:0097191; GO:0097194; GO:0097199; GO:0097200; GO:0097202; GO:0097264; GO:0097284; GO:0097342; GO:1901216; GO:2001233; GO:2001238 26208 XM_029337387.2 3852 3369 2749 3563 2481 Q5E960 1.19e-46 Zinc transporter ZIP3 (Solute carrier family 39 member 3) (Zrt- and Irt-like protein 3) (ZIP-3) Bos taurus (Bovine) zinc ion transmembrane transport [GO:0071577] GO:0005385; GO:0005886; GO:0016020; GO:0071577 26209 XM_044307379.1 997 708 633 1328 810 E9Q309 1.33e-38 Centrosome-associated protein 350 (Cep350) Mus musculus (Mouse) microtubule anchoring [GO:0034453]; non-motile cilium assembly [GO:1905515]; protein localization to centrosome [GO:0071539] GO:0005634; GO:0005737; GO:0005813; GO:0005814; GO:0005819; GO:0008017; GO:0034453; GO:0042995; GO:0071539; GO:1905515 26210 XM_044307379.1 997 708 633 1328 810 E9Q309 2.66e-24 Centrosome-associated protein 350 (Cep350) Mus musculus (Mouse) microtubule anchoring [GO:0034453]; non-motile cilium assembly [GO:1905515]; protein localization to centrosome [GO:0071539] GO:0005634; GO:0005737; GO:0005813; GO:0005814; GO:0005819; GO:0008017; GO:0034453; GO:0042995; GO:0071539; GO:1905515 26211 XM_029340338.2 0 23 0 0 0 Q9R1C8 5.38e-23 5-hydroxytryptamine receptor 6 (5-HT-6) (5-HT6) (Serotonin receptor 6) Mus musculus (Mouse) cerebral cortex cell migration [GO:0021795]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; learning [GO:0007612]; long-term synaptic potentiation [GO:0060291]; negative regulation of acetylcholine secretion, neurotransmission [GO:0014058]; negative regulation of gamma-aminobutyric acid secretion [GO:0014053]; negative regulation of glutamate secretion [GO:0014050]; positive regulation of dopamine secretion [GO:0033603]; positive regulation of gamma-aminobutyric acid secretion [GO:0014054]; positive regulation of TOR signaling [GO:0032008] GO:0004993; GO:0005886; GO:0005929; GO:0007187; GO:0007268; GO:0007612; GO:0014050; GO:0014053; GO:0014054; GO:0014058; GO:0021795; GO:0030425; GO:0030594; GO:0032008; GO:0033603; GO:0045202; GO:0060291 26212 XM_044316258.1 41 4 14 28 52 NA NA NA NA NA NA 26213 XM_029338614.2 28 13 32 37 43 NA NA NA NA NA NA 26214 XR_006393008.1 41 2 25 5 151 NA NA NA NA NA NA 26215 XM_029334658.2 0 4 186 89 0 O32210 1.83e-69 Glyoxal reductase (GR) (EC 1.1.1.-) (Methylglyoxal reductase) (EC 1.1.1.283) Bacillus subtilis (strain 168) NA GO:0043892 26216 XM_044321527.1 46 18 12 98 100 A6QLD2 1.11e-52 Olfactomedin-like protein 2B Bos taurus (Bovine) extracellular matrix organization [GO:0030198]; signal transduction [GO:0007165] GO:0005615; GO:0007165; GO:0030198; GO:0031012; GO:0042802; GO:0050840 26217 XR_003824269.2 63 10 33 59 23 NA NA NA NA NA NA 26218 XM_044325432.1 3811 4327 3134 4238 3604 Q3SZ45 1.23e-78 Stromal cell-derived factor 2 (SDF-2) Bos taurus (Bovine) NA GO:0005576 26219 XM_029353238.2 35 382 12 12 131 Q4QRK0 0 Methionine aminopeptidase 1 (MAP 1) (MetAP 1) (EC 3.4.11.18) (Peptidase M 1) Danio rerio (Zebrafish) (Brachydanio rerio) protein initiator methionine removal involved in protein maturation [GO:0035551] GO:0005829; GO:0035551; GO:0046872; GO:0070006 26220 XM_044309456.1 6717 3107 1355 2377 2117 NA NA NA NA NA NA 26221 XM_029342150.2 133 251 35 141 129 Q9P0M2 1.17e-26 A-kinase anchor protein 7 isoform gamma (AKAP-7 isoform gamma) (A-kinase anchor protein 18 kDa) (AKAP 18) (Protein kinase A-anchoring protein 7 isoform gamma) (PRKA7 isoform gamma) Homo sapiens (Human) modulation of chemical synaptic transmission [GO:0050804]; regulation of protein kinase A signaling [GO:0010738] GO:0000166; GO:0005634; GO:0005829; GO:0010738; GO:0019901; GO:0032991; GO:0034237; GO:0050804; GO:0051018; GO:0098686 26222 XR_006396383.1 915 545 770 827 575 Q8TDB6 3.53e-64 E3 ubiquitin-protein ligase DTX3L (EC 2.3.2.27) (B-lymphoma- and BAL-associated protein) (Protein deltex-3-like) (RING-type E3 ubiquitin transferase DTX3L) (Rhysin-2) (Rhysin2) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; defense response to virus [GO:0051607]; DNA damage checkpoint signaling [GO:0000077]; double-strand break repair [GO:0006302]; endosome to lysosome transport [GO:0008333]; histone H2A ubiquitination [GO:0033522]; histone H2B ubiquitination [GO:0033523]; histone monoubiquitination [GO:0010390]; innate immune response [GO:0045087]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; Notch signaling pathway [GO:0007219]; positive regulation of chromatin binding [GO:0035563]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of receptor catabolic process [GO:2000646]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein transport [GO:0015031]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000077; GO:0002230; GO:0004842; GO:0004857; GO:0005634; GO:0005654; GO:0005737; GO:0005764; GO:0005765; GO:0005829; GO:0006302; GO:0006325; GO:0006511; GO:0006974; GO:0007219; GO:0008333; GO:0010390; GO:0015031; GO:0016567; GO:0019899; GO:0031901; GO:0032092; GO:0032991; GO:0033522; GO:0033523; GO:0035563; GO:0042393; GO:0044389; GO:0045087; GO:0045893; GO:0046872; GO:0051444; GO:0051607; GO:0051865; GO:0061630; GO:0070936; GO:0097677; GO:0140768; GO:1900182; GO:1902966; GO:2000646 26223 XM_029338514.2 80 46 52 97 105 NA NA NA NA NA NA 26224 XM_044326254.1 40 12 18 65 7 C3VPR6 6.49e-26 Protein NLRC5 Mus musculus (Mouse) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of type II interferon-mediated signaling pathway [GO:0060335]; regulation of kinase activity [GO:0043549]; response to bacterium [GO:0009617] GO:0000978; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0009617; GO:0032088; GO:0035556; GO:0043549; GO:0045087; GO:0045345; GO:0045944; GO:0051607; GO:0060335; GO:0060339; GO:0060340 26225 XM_044327457.1 0 0 21 0 34 F8J3H2 3.48e-24 NA NA NA NA 26226 XM_029345080.2 310 140 5 160 60 Q6BZW3 1.05e-30 Protein BTN1 Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica) L-arginine transmembrane transport [GO:1903826]; lysine transport [GO:0015819]; regulation of intracellular pH [GO:0051453] GO:0000324; GO:0005773; GO:0005774; GO:0015819; GO:0022857; GO:0051453; GO:1903826 26227 XR_006396593.1 0 0 0 6 2 NA NA NA NA NA NA 26228 XM_044309072.1 77 16 32 23 39 NA NA NA NA NA NA 26229 XM_029332360.2 8 1 20 5 21 NA NA NA NA NA NA 26230 XM_044321547.1 0 0 3 0 42 NA NA NA NA NA NA 26231 XM_044315955.1 14 31 48 12 32 NA NA NA NA NA NA 26232 XM_029354475.2 302 327 205 265 472 NA NA NA NA NA NA 26233 XM_044318717.1 19 30 12 0 0 Q8WV92 2.49e-89 MIT domain-containing protein 1 Homo sapiens (Human) midbody abscission [GO:0061952]; mitotic cytokinesis [GO:0000281]; negative regulation of protein binding [GO:0032091] GO:0000281; GO:0019898; GO:0019904; GO:0030496; GO:0031902; GO:0032091; GO:0035091; GO:0042802; GO:0043231; GO:0061952; GO:0070062 26234 XM_029336753.2 124 80 40 96 63 Q5ZIL9 1.03e-154 KIF-binding protein (KIF1-binding protein) Gallus gallus (Chicken) central nervous system projection neuron axonogenesis [GO:0021952]; microtubule cytoskeleton organization [GO:0000226]; mitochondrial transport [GO:0006839]; neuron projection maintenance [GO:1990535] GO:0000226; GO:0005739; GO:0005856; GO:0006839; GO:0019894; GO:0021952; GO:1990535 26235 XM_044314037.1 0 0 0 0 6 NA NA NA NA NA NA 26236 XM_029332166.2 20 4 23 0 14 NA NA NA NA NA NA 26237 XM_029358335.2 319 594 391 455 459 NA NA NA NA NA NA 26238 XM_044313393.1 22 0 14 0 55 NA NA NA NA NA NA 26239 XM_029351461.2 67 0 0 89 7 NA NA NA NA NA NA 26240 XM_044308287.1 476 183 215 310 430 NA NA NA NA NA NA 26241 XM_029340427.2 0 114 0 2 30 NA NA NA NA NA NA 26242 XM_044316132.1 0 0 17 0 3 NA NA NA NA NA NA 26243 XM_044310940.1 0 2 1 11 10 NA NA NA NA NA NA 26244 XM_029337118.2 227 114 150 175 246 A0JML8 4.95e-50 DALR anticodon-binding domain-containing protein 3 Danio rerio (Zebrafish) (Brachydanio rerio) arginyl-tRNA aminoacylation [GO:0006420]; tRNA C3-cytosine methylation [GO:0106217] GO:0000049; GO:0004814; GO:0005524; GO:0006420; GO:0106217 26245 XM_044310740.1 0 0 9 0 0 NA NA NA NA NA NA 26246 XM_029343305.2 36 0 0 0 75 Q9D0R9 8.59e-38 WD repeat-containing protein 89 Mus musculus (Mouse) corpus callosum development [GO:0022038]; ventricular system development [GO:0021591] GO:0021591; GO:0022038 26247 XM_029354950.2 0 26 0 33 13 NA NA NA NA NA NA 26248 XR_003823371.1 1 20 82 5 9 NA NA NA NA NA NA 26249 XM_029342013.2 148 104 56 158 238 NA NA NA NA NA NA 26250 XM_044317354.1 74 111 40 185 116 NA NA NA NA NA NA 26251 XM_044321410.1 809 627 111 293 645 J7GQ11 2.49e-76 L-tyrosine decarboxylase (TDC) (EC 4.1.1.25) Levilactobacillus brevis (Lactobacillus brevis) carboxylic acid metabolic process [GO:0019752] GO:0004837; GO:0019752; GO:0030170; GO:0036468 26252 XM_029329003.2 132 53 84 111 34 Q8BG58 8.24e-75 Transmembrane prolyl 4-hydroxylase (P4H-TM) (EC 1.14.11.29) (Hypoxia-inducible factor prolyl hydroxylase 4) (HIF-PH4) (HIF-prolyl hydroxylase 4) (HPH-4) Mus musculus (Mouse) peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; regulation of erythrocyte differentiation [GO:0045646] GO:0004656; GO:0005506; GO:0005509; GO:0005783; GO:0005789; GO:0016706; GO:0018401; GO:0031418; GO:0045646 26253 XM_029323891.2 22 33 14 43 38 F6QEU4 2.54e-54 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 26254 XR_003826565.2 1113 1604 1024 1636 1265 NA NA NA NA NA NA 26255 XM_029330663.2 263 102 130 303 339 Q9H490 1.13e-103 Phosphatidylinositol glycan anchor biosynthesis class U protein (Cell division cycle protein 91-like 1) (Protein CDC91-like 1) (GPI transamidase component PIG-U) Homo sapiens (Human) attachment of GPI anchor to protein [GO:0016255]; GPI anchor biosynthetic process [GO:0006506]; protein localization to cell surface [GO:0034394]; regulation of receptor signaling pathway via JAK-STAT [GO:0046425] GO:0005789; GO:0005886; GO:0006506; GO:0016020; GO:0016255; GO:0034394; GO:0042765; GO:0046425 26256 XM_044316893.1 9 4 9 2 0 NA NA NA NA NA NA 26257 XM_029340098.2 20 3 7 1 47 P51049 2.85e-24 Melatonin receptor type 1B-B (Mel-1B-R-B) (Mel1b receptor B) (Melatonin receptor Mel1b Z2.6-4) (zMel1b-1) Danio rerio (Zebrafish) (Brachydanio rerio) G protein-coupled receptor signaling pathway [GO:0007186]; rhythmic process [GO:0048511] GO:0004930; GO:0005886; GO:0007186; GO:0008502; GO:0048511 26258 XM_044314659.1 145 25 398 411 85 NA NA NA NA NA NA 26259 XM_044316979.1 728 515 434 581 753 Q14191 0 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN (DNA helicase, RecQ-like type 3) (RecQ protein-like 2) (Werner syndrome protein) [Includes: 3'-5' exonuclease (EC 3.1.-.-); ATP-dependent helicase (EC 3.6.4.12)] Homo sapiens (Human) aging [GO:0007568]; base-excision repair [GO:0006284]; brain development [GO:0007420]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; cellular response to starvation [GO:0009267]; cellular senescence [GO:0090398]; DNA duplex unwinding [GO:0032508]; DNA metabolic process [GO:0006259]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; G-quadruplex DNA unwinding [GO:0044806]; multicellular organism aging [GO:0010259]; positive regulation of hydrolase activity [GO:0051345]; positive regulation of strand invasion [GO:0098530]; protein localization to nucleolus [GO:1902570]; regulation of growth rate [GO:0040009]; replication fork processing [GO:0031297]; replicative senescence [GO:0090399]; response to oxidative stress [GO:0006979]; response to UV-C [GO:0010225]; t-circle formation [GO:0090656]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; telomeric D-loop disassembly [GO:0061820] GO:0000287; GO:0000400; GO:0000403; GO:0000405; GO:0000723; GO:0000724; GO:0000731; GO:0000781; GO:0003677; GO:0003678; GO:0003682; GO:0004527; GO:0005524; GO:0005634; GO:0005654; GO:0005657; GO:0005694; GO:0005730; GO:0005737; GO:0005813; GO:0006259; GO:0006260; GO:0006268; GO:0006281; GO:0006284; GO:0006302; GO:0006310; GO:0006974; GO:0006979; GO:0007420; GO:0007568; GO:0008408; GO:0009267; GO:0009378; GO:0010225; GO:0010259; GO:0016607; GO:0016887; GO:0030145; GO:0031297; GO:0032201; GO:0032405; GO:0032508; GO:0040009; GO:0042803; GO:0043005; GO:0043138; GO:0044806; GO:0044877; GO:0051345; GO:0051880; GO:0061749; GO:0061820; GO:0061821; GO:0061849; GO:0070337; GO:0071480; GO:0090398; GO:0090399; GO:0090656; GO:0098530; GO:1902570; GO:1905773 26260 XM_029348264.2 548 485 442 609 727 NA NA NA NA NA NA 26261 XM_044328200.1 215 112 221 125 17 Q8C428 3.29e-81 Transmembrane channel-like protein 7 Mus musculus (Mouse) NA GO:0005886; GO:0008381 26262 XR_003824090.2 22 13 41 29 186 NA NA NA NA NA NA 26263 XR_006394841.1 11 14 27 1 34 NA NA NA NA NA NA 26264 XM_029356704.2 0 0 9 2 35 Q9WUV0 1.04e-115 Origin recognition complex subunit 5 Mus musculus (Mouse) DNA replication [GO:0006260]; DNA replication initiation [GO:0006270]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0000808; GO:0003688; GO:0005524; GO:0005654; GO:0005664; GO:0005829; GO:0006260; GO:0006270; GO:0006275 26265 XR_006397723.1 0 58 0 194 628 NA NA NA NA NA NA 26266 XM_029358614.2 148 30 14 32 65 Q9I830 1.32e-111 Potassium voltage-gated channel subfamily A member 2 (Shaker-related potassium channel tsha1) (Trout shaker 1) (Voltage-gated potassium channel subunit Kv1.2) Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) neuronal action potential [GO:0019228]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005251; GO:0005886; GO:0008076; GO:0019228; GO:0034765; GO:0044224; GO:0051260; GO:0071805 26267 XM_044310791.1 17 0 7 13 24 NA NA NA NA NA NA 26268 XM_044320876.1 458 259 164 91 120 NA NA NA NA NA NA 26269 XM_044313642.1 0 55 28 0 0 NA NA NA NA NA NA 26270 XM_029349817.2 574 349 316 347 533 Q9P2S5 0 WD repeat-containing protein WRAP73 (WD repeat-containing protein 8) (WD repeat-containing protein antisense to TP73 gene) Homo sapiens (Human) cell projection organization [GO:0030030]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly [GO:0090307]; positive regulation of non-motile cilium assembly [GO:1902857]; protein localization to mitotic spindle pole body [GO:1902440] GO:0000070; GO:0005737; GO:0005813; GO:0005814; GO:0005815; GO:0030030; GO:0036064; GO:0072686; GO:0090307; GO:1902440; GO:1902857; GO:1990811 26271 XR_003828302.2 496 527 69 612 95 NA NA NA NA NA NA 26272 XM_029346838.2 436 532 164 363 255 Q0P426 6.58e-22 Spindle and kinetochore-associated protein 2 (Protein FAM33A) Danio rerio (Zebrafish) (Brachydanio rerio) cell division [GO:0051301]; chromosome segregation [GO:0007059]; mitotic cell cycle [GO:0000278]; regulation of microtubule polymerization or depolymerization [GO:0031110] GO:0000278; GO:0000940; GO:0005737; GO:0005876; GO:0007059; GO:0008017; GO:0031110; GO:0051301 26273 XR_006394959.1 238 538 239 541 648 Q8N4B1 1.79e-23 Sesquipedalian-1 (Ses1) (27 kDa inositol polyphosphate phosphatase-interacting protein A) (IPIP27A) (PH domain-containing endocytic trafficking adaptor 1) Homo sapiens (Human) endosome organization [GO:0007032]; receptor recycling [GO:0001881]; retrograde transport, endosome to Golgi [GO:0042147] GO:0001881; GO:0005769; GO:0005802; GO:0005829; GO:0007032; GO:0030136; GO:0042147; GO:0042803; GO:0055037 26274 XM_044313934.1 0 0 0 13 30 NA NA NA NA NA NA 26275 XM_044328054.1 9 0 0 1 1 E9Q236 2.84e-34 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 26276 XM_029351650.2 35 0 0 27 0 NA NA NA NA NA NA 26277 XM_029349737.2 757 1095 811 1556 958 Q969X6 6.69e-133 U3 small nucleolar RNA-associated protein 4 homolog (Cirhin) (UTP4 small subunit processome component) Homo sapiens (Human) maturation of SSU-rRNA [GO:0030490]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; regulation of DNA-templated transcription [GO:0006355] GO:0000462; GO:0001650; GO:0003723; GO:0005654; GO:0005694; GO:0005730; GO:0006355; GO:0030490; GO:0030686; GO:0032040; GO:0034455 26278 XM_029346358.2 50 36 11 17 63 NA NA NA NA NA NA 26279 XM_029339188.2 1042 1244 493 998 403 P02594 2.15e-67 Calmodulin (CaM) Electrophorus electricus (Electric eel) (Gymnotus electricus) NA GO:0005509 26280 XM_029339188.2 1042 1244 493 998 403 P02594 1.01e-58 Calmodulin (CaM) Electrophorus electricus (Electric eel) (Gymnotus electricus) NA GO:0005509 26281 XM_029339188.2 1042 1244 493 998 403 P02594 1.79e-29 Calmodulin (CaM) Electrophorus electricus (Electric eel) (Gymnotus electricus) NA GO:0005509 26282 XM_044321800.1 1795 832 660 1518 1374 Q60HE9 0 Lysosomal alpha-mannosidase (Laman) (EC 3.2.1.24) (Lysosomal acid alpha-mannosidase) (Mannosidase alpha class 2B member 1) (Mannosidase alpha-B) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) mannose metabolic process [GO:0006013] GO:0004559; GO:0005764; GO:0006013; GO:0030246; GO:0046872 26283 XM_044321800.1 1795 832 660 1518 1374 Q60HE9 3.71e-56 Lysosomal alpha-mannosidase (Laman) (EC 3.2.1.24) (Lysosomal acid alpha-mannosidase) (Mannosidase alpha class 2B member 1) (Mannosidase alpha-B) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) mannose metabolic process [GO:0006013] GO:0004559; GO:0005764; GO:0006013; GO:0030246; GO:0046872 26284 XM_044321800.1 1795 832 660 1518 1374 Q60HE9 3.71e-56 Lysosomal alpha-mannosidase (Laman) (EC 3.2.1.24) (Lysosomal acid alpha-mannosidase) (Mannosidase alpha class 2B member 1) (Mannosidase alpha-B) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) mannose metabolic process [GO:0006013] GO:0004559; GO:0005764; GO:0006013; GO:0030246; GO:0046872 26285 XM_044314600.1 61 1 10 11 49 NA NA NA NA NA NA 26286 XM_029340614.2 0 0 3 0 14 NA NA NA NA NA NA 26287 XR_003827023.2 130 106 149 156 295 NA NA NA NA NA NA 26288 XM_044311938.1 199 112 86 35 151 Q6NUT3 8.37e-45 Major facilitator superfamily domain-containing protein 12 Homo sapiens (Human) carbohydrate transport [GO:0008643]; cysteine transmembrane transport [GO:1903712]; melanin biosynthetic process [GO:0042438]; negative regulation of melanin biosynthetic process [GO:0048022]; organic substance transport [GO:0071702]; pigment metabolic process involved in pigmentation [GO:0043474]; regulation of melanin biosynthetic process [GO:0048021] GO:0005764; GO:0005765; GO:0005770; GO:0005886; GO:0008643; GO:0015293; GO:0033162; GO:0033229; GO:0042438; GO:0042470; GO:0043474; GO:0048021; GO:0048022; GO:0071702; GO:1903712 26289 XM_044311938.1 199 112 86 35 151 Q6NUT3 3.86e-36 Major facilitator superfamily domain-containing protein 12 Homo sapiens (Human) carbohydrate transport [GO:0008643]; cysteine transmembrane transport [GO:1903712]; melanin biosynthetic process [GO:0042438]; negative regulation of melanin biosynthetic process [GO:0048022]; organic substance transport [GO:0071702]; pigment metabolic process involved in pigmentation [GO:0043474]; regulation of melanin biosynthetic process [GO:0048021] GO:0005764; GO:0005765; GO:0005770; GO:0005886; GO:0008643; GO:0015293; GO:0033162; GO:0033229; GO:0042438; GO:0042470; GO:0043474; GO:0048021; GO:0048022; GO:0071702; GO:1903712 26290 XR_006396707.1 21 6 0 34 11 NA NA NA NA NA NA 26291 XM_044322268.1 0 0 57 0 0 NA NA NA NA NA NA 26292 XM_044307840.1 1030 513 1155 803 889 Q9ESK9 1.08e-48 RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (FAK family kinase-interacting protein of 200 kDa) (FIP200) (LaXp180) Mus musculus (Mouse) apoptotic process [GO:0006915]; autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; autophagy of peroxisome [GO:0030242]; cell cycle [GO:0007049]; extrinsic apoptotic signaling pathway [GO:0097191]; glycophagy [GO:0061723]; heart development [GO:0007507]; liver development [GO:0001889]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; piecemeal microautophagy of the nucleus [GO:0034727]; positive regulation of autophagy [GO:0010508]; positive regulation of cell size [GO:0045793]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein phosphorylation [GO:0001934]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of protein lipidation [GO:1903059]; reticulophagy [GO:0061709] GO:0000045; GO:0000407; GO:0000421; GO:0000422; GO:0001889; GO:0001934; GO:0005634; GO:0005737; GO:0005764; GO:0005829; GO:0006468; GO:0006914; GO:0006915; GO:0007049; GO:0007507; GO:0008285; GO:0010508; GO:0019898; GO:0019901; GO:0030242; GO:0031965; GO:0034045; GO:0034727; GO:0043066; GO:0045793; GO:0046330; GO:0046777; GO:0060090; GO:0061709; GO:0061723; GO:0097191; GO:1903059; GO:1990316; GO:2001237 26293 XM_044307840.1 1030 513 1155 803 889 Q9ESK9 1.17e-28 RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (FAK family kinase-interacting protein of 200 kDa) (FIP200) (LaXp180) Mus musculus (Mouse) apoptotic process [GO:0006915]; autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; autophagy of peroxisome [GO:0030242]; cell cycle [GO:0007049]; extrinsic apoptotic signaling pathway [GO:0097191]; glycophagy [GO:0061723]; heart development [GO:0007507]; liver development [GO:0001889]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; piecemeal microautophagy of the nucleus [GO:0034727]; positive regulation of autophagy [GO:0010508]; positive regulation of cell size [GO:0045793]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein phosphorylation [GO:0001934]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of protein lipidation [GO:1903059]; reticulophagy [GO:0061709] GO:0000045; GO:0000407; GO:0000421; GO:0000422; GO:0001889; GO:0001934; GO:0005634; GO:0005737; GO:0005764; GO:0005829; GO:0006468; GO:0006914; GO:0006915; GO:0007049; GO:0007507; GO:0008285; GO:0010508; GO:0019898; GO:0019901; GO:0030242; GO:0031965; GO:0034045; GO:0034727; GO:0043066; GO:0045793; GO:0046330; GO:0046777; GO:0060090; GO:0061709; GO:0061723; GO:0097191; GO:1903059; GO:1990316; GO:2001237 26294 XM_044307840.1 1030 513 1155 803 889 Q9ESK9 8.37e-25 RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (FAK family kinase-interacting protein of 200 kDa) (FIP200) (LaXp180) Mus musculus (Mouse) apoptotic process [GO:0006915]; autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; autophagy of peroxisome [GO:0030242]; cell cycle [GO:0007049]; extrinsic apoptotic signaling pathway [GO:0097191]; glycophagy [GO:0061723]; heart development [GO:0007507]; liver development [GO:0001889]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; piecemeal microautophagy of the nucleus [GO:0034727]; positive regulation of autophagy [GO:0010508]; positive regulation of cell size [GO:0045793]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein phosphorylation [GO:0001934]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of protein lipidation [GO:1903059]; reticulophagy [GO:0061709] GO:0000045; GO:0000407; GO:0000421; GO:0000422; GO:0001889; GO:0001934; GO:0005634; GO:0005737; GO:0005764; GO:0005829; GO:0006468; GO:0006914; GO:0006915; GO:0007049; GO:0007507; GO:0008285; GO:0010508; GO:0019898; GO:0019901; GO:0030242; GO:0031965; GO:0034045; GO:0034727; GO:0043066; GO:0045793; GO:0046330; GO:0046777; GO:0060090; GO:0061709; GO:0061723; GO:0097191; GO:1903059; GO:1990316; GO:2001237 26295 XM_044311192.1 0 17 25 24 23 NA NA NA NA NA NA 26296 XR_003825033.2 5 61 4 5 19 NA NA NA NA NA NA 26297 XM_029332565.2 1081 799 624 857 913 Q5JSJ4 1.64e-173 Integrator complex subunit 6-like (Protein DDX26B) Homo sapiens (Human) snRNA 3'-end processing [GO:0034472] GO:0032039; GO:0034472 26298 XM_044328393.1 36 445 3832 321 392 NA NA NA NA NA NA 26299 XM_044326357.1 40 0 0 0 190 NA NA NA NA NA NA 26300 XM_044315208.1 32 29 12 48 29 NA NA NA NA NA NA 26301 XR_006391478.1 65 30 40 66 40 NA NA NA NA NA NA 26302 XR_006394546.1 0 10 17 4 10 NA NA NA NA NA NA 26303 XM_029338850.2 168 0 0 137 0 NA NA NA NA NA NA 26304 XM_044315890.1 198 55 33 138 72 Q14642 1.77e-121 Inositol polyphosphate-5-phosphatase A (EC 3.1.3.56) (43 kDa inositol polyphosphate 5-phosphatase) (Type I inositol 1,4,5-trisphosphate 5-phosphatase) (5PTase) Homo sapiens (Human) inositol phosphate dephosphorylation [GO:0046855]; inositol phosphate metabolic process [GO:0043647]; inositol phosphate-mediated signaling [GO:0048016]; negative regulation of neuron death [GO:1901215]; phosphatidylinositol dephosphorylation [GO:0046856] GO:0004445; GO:0005886; GO:0016020; GO:0030425; GO:0042731; GO:0043647; GO:0046855; GO:0046856; GO:0048016; GO:0052658; GO:0052659; GO:1901215 26305 XM_029351035.2 688 850 792 1463 1741 NA NA NA NA NA NA 26306 XM_029332237.2 9356 3956 4153 4990 2052 P41439 2.04e-43 Folate receptor gamma (FR-gamma) (Folate receptor 3) Homo sapiens (Human) cell adhesion [GO:0007155]; folic acid transport [GO:0015884]; fusion of sperm to egg plasma membrane involved in single fertilization [GO:0007342]; sperm-egg recognition [GO:0035036] GO:0005542; GO:0005576; GO:0007155; GO:0007342; GO:0009897; GO:0015884; GO:0016020; GO:0019898; GO:0035036; GO:0035580; GO:0038023; GO:1904724 26307 XM_044321683.1 21 23 7 0 0 E2JA28 1.87e-36 Dapdiamide synthesis protein DdaC (EC 1.-.-.-) Enterobacter agglomerans (Erwinia herbicola) (Pantoea agglomerans) antibiotic biosynthetic process [GO:0017000] GO:0016491; GO:0017000 26308 XM_044311417.1 0 0 23 25 19 NA NA NA NA NA NA 26309 XM_029340455.2 310 154 126 280 61 Q80XJ3 7.1e-124 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 26310 XM_029340455.2 310 154 126 280 61 Q80XJ3 1.62e-79 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 26311 XM_029340455.2 310 154 126 280 61 Q80XJ3 1.04e-66 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 26312 XM_044316624.1 98 82 45 105 202 A0JPI9 9.98e-81 Leucine-rich repeat-containing protein 74A (Leucine-rich repeat-containing protein 74) Rattus norvegicus (Rat) NA NA 26313 XM_044317407.1 92 266 120 382 192 NA NA NA NA NA NA 26314 XM_044319351.1 158 78 45 59 202 NA NA NA NA NA NA 26315 XM_044311817.1 4 1 0 12 0 B8VIU6 8.52e-42 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 26316 XM_029340883.2 304 305 149 375 188 NA NA NA NA NA NA 26317 XM_029342775.2 0 0 61 0 0 Q3T106 4.85e-26 Serine/arginine-rich splicing factor 7 (Splicing factor, arginine/serine-rich 7) Bos taurus (Bovine) cellular response to leukemia inhibitory factor [GO:1990830]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of mRNA splicing, via spliceosome [GO:0048025] GO:0000398; GO:0003723; GO:0005737; GO:0008270; GO:0016607; GO:0019904; GO:0048025; GO:0051028; GO:1990830 26318 XM_044327501.1 30 40 13 80 15 NA NA NA NA NA NA 26319 XM_044326391.1 17 13 28 122 176 NA NA NA NA NA NA 26320 XM_044327574.1 27 8 0 6 0 Q94K49 1.15e-23 Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1 (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) epigenetic regulation of gene expression [GO:0040029] GO:0003682; GO:0004518; GO:0005634; GO:0035098; GO:0035102; GO:0040029; GO:0046872 26321 XM_044318472.1 80 60 54 96 32 A9ZSY3 4.69e-89 Facilitated trehalose transporter Tret1 (BmTRET1) Bombyx mori (Silk moth) trehalose transport [GO:0015771] GO:0005886; GO:0015574; GO:0015771; GO:0051119 26322 XM_029333728.2 313 219 118 389 350 Q5U3G6 7.64e-102 Protein YIF1B (YIP1-interacting factor homolog B) Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; protein transport [GO:0015031]; sperm flagellum assembly [GO:0120316] GO:0000139; GO:0005783; GO:0005789; GO:0005793; GO:0005794; GO:0006888; GO:0015031; GO:0030134; GO:0033116; GO:0060271; GO:0120316 26323 XR_006392856.1 22 44 9 6 45 NA NA NA NA NA NA 26324 XM_029349271.2 209 419 595 139 3 Q9UHJ3 9.63e-83 Scm-like with four MBT domains protein 1 (hSFMBT) (Renal ubiquitous protein 1) Homo sapiens (Human) cell differentiation [GO:0030154]; chromatin organization [GO:0006325]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of muscle organ development [GO:0048635]; spermatogenesis [GO:0007283] GO:0003682; GO:0003714; GO:0005634; GO:0005654; GO:0006325; GO:0007283; GO:0030154; GO:0042393; GO:0045892; GO:0048635 26325 XM_044308195.1 2 0 0 823 300 Q9V9A7 8.71e-164 Probable methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCase subunit beta) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 2) (3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta) Drosophila melanogaster (Fruit fly) coenzyme A metabolic process [GO:0015936]; leucine catabolic process [GO:0006552]; regulation of eclosion [GO:0007563] GO:0004485; GO:0005524; GO:0005739; GO:0005759; GO:0006552; GO:0007563; GO:0015936; GO:1905202 26326 XM_029335991.2 66 218 189 270 0 P49815 0 Tuberin (Tuberous sclerosis 2 protein) Homo sapiens (Human) anoikis [GO:0043276]; endocytosis [GO:0006897]; heart development [GO:0007507]; insulin-like growth factor receptor signaling pathway [GO:0048009]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of mitophagy [GO:1901525]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of Wnt signaling pathway [GO:0030178]; neural tube closure [GO:0001843]; positive chemotaxis [GO:0050918]; positive regulation of GTPase activity [GO:0043547]; positive regulation of macroautophagy [GO:0016239]; protein import into nucleus [GO:0006606]; protein kinase B signaling [GO:0043491]; protein localization [GO:0008104]; regulation of cell cycle [GO:0051726]; regulation of endocytosis [GO:0030100]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of small GTPase mediated signal transduction [GO:0051056]; vesicle-mediated transport [GO:0016192] GO:0001843; GO:0005096; GO:0005634; GO:0005737; GO:0005764; GO:0005794; GO:0005829; GO:0006469; GO:0006606; GO:0006897; GO:0007507; GO:0008104; GO:0008285; GO:0014067; GO:0014069; GO:0016020; GO:0016192; GO:0016239; GO:0019902; GO:0030100; GO:0030178; GO:0031267; GO:0032007; GO:0033596; GO:0042803; GO:0043276; GO:0043491; GO:0043547; GO:0046626; GO:0046627; GO:0048009; GO:0048471; GO:0050918; GO:0051056; GO:0051726; GO:0051879; GO:0051898; GO:1901525 26327 XM_029335991.2 66 218 189 270 0 P49815 4.88e-83 Tuberin (Tuberous sclerosis 2 protein) Homo sapiens (Human) anoikis [GO:0043276]; endocytosis [GO:0006897]; heart development [GO:0007507]; insulin-like growth factor receptor signaling pathway [GO:0048009]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of mitophagy [GO:1901525]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of Wnt signaling pathway [GO:0030178]; neural tube closure [GO:0001843]; positive chemotaxis [GO:0050918]; positive regulation of GTPase activity [GO:0043547]; positive regulation of macroautophagy [GO:0016239]; protein import into nucleus [GO:0006606]; protein kinase B signaling [GO:0043491]; protein localization [GO:0008104]; regulation of cell cycle [GO:0051726]; regulation of endocytosis [GO:0030100]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of small GTPase mediated signal transduction [GO:0051056]; vesicle-mediated transport [GO:0016192] GO:0001843; GO:0005096; GO:0005634; GO:0005737; GO:0005764; GO:0005794; GO:0005829; GO:0006469; GO:0006606; GO:0006897; GO:0007507; GO:0008104; GO:0008285; GO:0014067; GO:0014069; GO:0016020; GO:0016192; GO:0016239; GO:0019902; GO:0030100; GO:0030178; GO:0031267; GO:0032007; GO:0033596; GO:0042803; GO:0043276; GO:0043491; GO:0043547; GO:0046626; GO:0046627; GO:0048009; GO:0048471; GO:0050918; GO:0051056; GO:0051726; GO:0051879; GO:0051898; GO:1901525 26328 XM_044322490.1 12 0 0 12 0 NA NA NA NA NA NA 26329 XM_044328404.1 43 13 44 140 64 NA NA NA NA NA NA 26330 XM_044315230.1 17 22 25 15 25 NA NA NA NA NA NA 26331 XM_029356554.2 828 493 293 731 1237 Q86U44 1.74e-179 N6-adenosine-methyltransferase catalytic subunit (EC 2.1.1.348) (Methyltransferase-like protein 3) (hMETTL3) (N6-adenosine-methyltransferase 70 kDa subunit) (MT-A70) Homo sapiens (Human) adenosine to inosine editing [GO:0006382]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; circadian rhythm [GO:0007623]; dosage compensation by inactivation of X chromosome [GO:0009048]; endothelial to hematopoietic transition [GO:0098508]; forebrain radial glial cell differentiation [GO:0021861]; gliogenesis [GO:0042063]; innate immune response [GO:0045087]; mRNA catabolic process [GO:0006402]; mRNA destabilization [GO:0061157]; mRNA methylation [GO:0080009]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; oogenesis [GO:0048477]; positive regulation of cap-independent translational initiation [GO:1903679]; positive regulation of translation [GO:0045727]; primary miRNA processing [GO:0031053]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of meiotic cell cycle [GO:0051445]; regulation of T cell differentiation [GO:0045580]; RNA methylation [GO:0001510]; spermatogenesis [GO:0007283]; stem cell population maintenance [GO:0019827] GO:0000398; GO:0001510; GO:0001734; GO:0003729; GO:0005634; GO:0005654; GO:0005737; GO:0006382; GO:0006397; GO:0006402; GO:0006974; GO:0007283; GO:0007623; GO:0008168; GO:0008173; GO:0009048; GO:0016422; GO:0016607; GO:0019827; GO:0021861; GO:0031053; GO:0034644; GO:0036396; GO:0042063; GO:0045087; GO:0045580; GO:0045727; GO:0045746; GO:0046982; GO:0048477; GO:0051445; GO:0060339; GO:0061157; GO:0080009; GO:0098508; GO:1902036; GO:1903679; GO:1904047 26332 XR_006397978.1 10 5 0 14 6 NA NA NA NA NA NA 26333 XM_044328569.1 1381 974 738 1248 1417 Q7ZX59 1.42e-51 Cytokine receptor-like factor 3 Xenopus laevis (African clawed frog) NA GO:0005737 26334 XM_029356136.2 0 0 31 101 35 NA NA NA NA NA NA 26335 XM_029331725.2 619 1959 1966 1693 2963 NA NA NA NA NA NA 26336 XM_029358189.2 276 145 120 283 248 Q9EQQ3 1.52e-79 Probable G-protein coupled receptor 63 (PSP24-2) (PSP24-beta) Mus musculus (Mouse) G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0005654; GO:0005829; GO:0005886; GO:0007186; GO:0016020; GO:0043235 26337 XM_029344224.2 303 236 220 239 163 P42700 0 RNA-binding protein RO60 (60 kDa SS-A/Ro ribonucleoprotein) (60 kDa Ro protein) (60 kDa ribonucleoprotein Ro) (RoRNP) (TROVE domain family member 2) Xenopus laevis (African clawed frog) cell projection organization [GO:0030030] GO:0005737; GO:0030030; GO:0034336; GO:0046872; GO:1990904 26338 XM_044309658.1 384 833 482 614 425 Q99466 1.5e-51 Neurogenic locus notch homolog protein 4 (Notch 4) (hNotch4) [Cleaved into: Notch 4 extracellular truncation; Notch 4 intracellular domain] Homo sapiens (Human) branching involved in blood vessel morphogenesis [GO:0001569]; cell differentiation [GO:0030154]; cell fate determination [GO:0001709]; endothelial cell morphogenesis [GO:0001886]; epithelial to mesenchymal transition [GO:0001837]; hemopoiesis [GO:0030097]; mammary gland development [GO:0030879]; morphogenesis of a branching structure [GO:0001763]; negative regulation of cell adhesion molecule production [GO:0060354]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of endothelial cell differentiation [GO:0045602]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription of Notch receptor target [GO:0007221]; vasculature development [GO:0001944]; wound healing [GO:0042060] GO:0000122; GO:0000139; GO:0001569; GO:0001709; GO:0001763; GO:0001837; GO:0001886; GO:0001944; GO:0005112; GO:0005509; GO:0005576; GO:0005634; GO:0005654; GO:0005789; GO:0005829; GO:0005886; GO:0007221; GO:0009986; GO:0030097; GO:0030154; GO:0030879; GO:0038023; GO:0042060; GO:0045596; GO:0045602; GO:0045893; GO:0060354; GO:2000048 26339 XM_044309658.1 384 833 482 614 425 Q99466 1.71e-44 Neurogenic locus notch homolog protein 4 (Notch 4) (hNotch4) [Cleaved into: Notch 4 extracellular truncation; Notch 4 intracellular domain] Homo sapiens (Human) branching involved in blood vessel morphogenesis [GO:0001569]; cell differentiation [GO:0030154]; cell fate determination [GO:0001709]; endothelial cell morphogenesis [GO:0001886]; epithelial to mesenchymal transition [GO:0001837]; hemopoiesis [GO:0030097]; mammary gland development [GO:0030879]; morphogenesis of a branching structure [GO:0001763]; negative regulation of cell adhesion molecule production [GO:0060354]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of endothelial cell differentiation [GO:0045602]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription of Notch receptor target [GO:0007221]; vasculature development [GO:0001944]; wound healing [GO:0042060] GO:0000122; GO:0000139; GO:0001569; GO:0001709; GO:0001763; GO:0001837; GO:0001886; GO:0001944; GO:0005112; GO:0005509; GO:0005576; GO:0005634; GO:0005654; GO:0005789; GO:0005829; GO:0005886; GO:0007221; GO:0009986; GO:0030097; GO:0030154; GO:0030879; GO:0038023; GO:0042060; GO:0045596; GO:0045602; GO:0045893; GO:0060354; GO:2000048 26340 XM_044309658.1 384 833 482 614 425 Q99466 1.74e-32 Neurogenic locus notch homolog protein 4 (Notch 4) (hNotch4) [Cleaved into: Notch 4 extracellular truncation; Notch 4 intracellular domain] Homo sapiens (Human) branching involved in blood vessel morphogenesis [GO:0001569]; cell differentiation [GO:0030154]; cell fate determination [GO:0001709]; endothelial cell morphogenesis [GO:0001886]; epithelial to mesenchymal transition [GO:0001837]; hemopoiesis [GO:0030097]; mammary gland development [GO:0030879]; morphogenesis of a branching structure [GO:0001763]; negative regulation of cell adhesion molecule production [GO:0060354]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of endothelial cell differentiation [GO:0045602]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription of Notch receptor target [GO:0007221]; vasculature development [GO:0001944]; wound healing [GO:0042060] GO:0000122; GO:0000139; GO:0001569; GO:0001709; GO:0001763; GO:0001837; GO:0001886; GO:0001944; GO:0005112; GO:0005509; GO:0005576; GO:0005634; GO:0005654; GO:0005789; GO:0005829; GO:0005886; GO:0007221; GO:0009986; GO:0030097; GO:0030154; GO:0030879; GO:0038023; GO:0042060; GO:0045596; GO:0045602; GO:0045893; GO:0060354; GO:2000048 26341 XM_044309658.1 384 833 482 614 425 Q99466 2.46e-32 Neurogenic locus notch homolog protein 4 (Notch 4) (hNotch4) [Cleaved into: Notch 4 extracellular truncation; Notch 4 intracellular domain] Homo sapiens (Human) branching involved in blood vessel morphogenesis [GO:0001569]; cell differentiation [GO:0030154]; cell fate determination [GO:0001709]; endothelial cell morphogenesis [GO:0001886]; epithelial to mesenchymal transition [GO:0001837]; hemopoiesis [GO:0030097]; mammary gland development [GO:0030879]; morphogenesis of a branching structure [GO:0001763]; negative regulation of cell adhesion molecule production [GO:0060354]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of endothelial cell differentiation [GO:0045602]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription of Notch receptor target [GO:0007221]; vasculature development [GO:0001944]; wound healing [GO:0042060] GO:0000122; GO:0000139; GO:0001569; GO:0001709; GO:0001763; GO:0001837; GO:0001886; GO:0001944; GO:0005112; GO:0005509; GO:0005576; GO:0005634; GO:0005654; GO:0005789; GO:0005829; GO:0005886; GO:0007221; GO:0009986; GO:0030097; GO:0030154; GO:0030879; GO:0038023; GO:0042060; GO:0045596; GO:0045602; GO:0045893; GO:0060354; GO:2000048 26342 XM_044309658.1 384 833 482 614 425 Q99466 4.61e-31 Neurogenic locus notch homolog protein 4 (Notch 4) (hNotch4) [Cleaved into: Notch 4 extracellular truncation; Notch 4 intracellular domain] Homo sapiens (Human) branching involved in blood vessel morphogenesis [GO:0001569]; cell differentiation [GO:0030154]; cell fate determination [GO:0001709]; endothelial cell morphogenesis [GO:0001886]; epithelial to mesenchymal transition [GO:0001837]; hemopoiesis [GO:0030097]; mammary gland development [GO:0030879]; morphogenesis of a branching structure [GO:0001763]; negative regulation of cell adhesion molecule production [GO:0060354]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of endothelial cell differentiation [GO:0045602]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription of Notch receptor target [GO:0007221]; vasculature development [GO:0001944]; wound healing [GO:0042060] GO:0000122; GO:0000139; GO:0001569; GO:0001709; GO:0001763; GO:0001837; GO:0001886; GO:0001944; GO:0005112; GO:0005509; GO:0005576; GO:0005634; GO:0005654; GO:0005789; GO:0005829; GO:0005886; GO:0007221; GO:0009986; GO:0030097; GO:0030154; GO:0030879; GO:0038023; GO:0042060; GO:0045596; GO:0045602; GO:0045893; GO:0060354; GO:2000048 26343 XM_044309658.1 384 833 482 614 425 Q99466 5.76e-29 Neurogenic locus notch homolog protein 4 (Notch 4) (hNotch4) [Cleaved into: Notch 4 extracellular truncation; Notch 4 intracellular domain] Homo sapiens (Human) branching involved in blood vessel morphogenesis [GO:0001569]; cell differentiation [GO:0030154]; cell fate determination [GO:0001709]; endothelial cell morphogenesis [GO:0001886]; epithelial to mesenchymal transition [GO:0001837]; hemopoiesis [GO:0030097]; mammary gland development [GO:0030879]; morphogenesis of a branching structure [GO:0001763]; negative regulation of cell adhesion molecule production [GO:0060354]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of endothelial cell differentiation [GO:0045602]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription of Notch receptor target [GO:0007221]; vasculature development [GO:0001944]; wound healing [GO:0042060] GO:0000122; GO:0000139; GO:0001569; GO:0001709; GO:0001763; GO:0001837; GO:0001886; GO:0001944; GO:0005112; GO:0005509; GO:0005576; GO:0005634; GO:0005654; GO:0005789; GO:0005829; GO:0005886; GO:0007221; GO:0009986; GO:0030097; GO:0030154; GO:0030879; GO:0038023; GO:0042060; GO:0045596; GO:0045602; GO:0045893; GO:0060354; GO:2000048 26344 XM_044309658.1 384 833 482 614 425 Q99466 2.31e-26 Neurogenic locus notch homolog protein 4 (Notch 4) (hNotch4) [Cleaved into: Notch 4 extracellular truncation; Notch 4 intracellular domain] Homo sapiens (Human) branching involved in blood vessel morphogenesis [GO:0001569]; cell differentiation [GO:0030154]; cell fate determination [GO:0001709]; endothelial cell morphogenesis [GO:0001886]; epithelial to mesenchymal transition [GO:0001837]; hemopoiesis [GO:0030097]; mammary gland development [GO:0030879]; morphogenesis of a branching structure [GO:0001763]; negative regulation of cell adhesion molecule production [GO:0060354]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of endothelial cell differentiation [GO:0045602]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription of Notch receptor target [GO:0007221]; vasculature development [GO:0001944]; wound healing [GO:0042060] GO:0000122; GO:0000139; GO:0001569; GO:0001709; GO:0001763; GO:0001837; GO:0001886; GO:0001944; GO:0005112; GO:0005509; GO:0005576; GO:0005634; GO:0005654; GO:0005789; GO:0005829; GO:0005886; GO:0007221; GO:0009986; GO:0030097; GO:0030154; GO:0030879; GO:0038023; GO:0042060; GO:0045596; GO:0045602; GO:0045893; GO:0060354; GO:2000048 26345 XR_006397502.1 25 2 13 18 9 NA NA NA NA NA NA 26346 XM_044317280.1 48 32 35 75 68 Q32KI9 8.21e-116 Arylsulfatase I (ASI) (EC 3.1.6.-) Mus musculus (Mouse) NA GO:0005576; GO:0005783; GO:0008484; GO:0046872 26347 XM_044308065.1 826 711 242 702 148 NA NA NA NA NA NA 26348 XM_029324407.2 4 10 2 12 23 NA NA NA NA NA NA 26349 XM_029339443.2 37 0 0 25 0 NA NA NA NA NA NA 26350 XM_044313338.1 15 0 25 22 5 NA NA NA NA NA NA 26351 XM_044310837.1 76 0 260 0 0 Q7RTR2 3.32e-72 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 26352 XM_044310837.1 76 0 260 0 0 Q7RTR2 1.35e-71 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 26353 XM_044310837.1 76 0 260 0 0 Q7RTR2 5.09e-64 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 26354 XM_044310837.1 76 0 260 0 0 Q7RTR2 1.65e-59 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 26355 XM_044310837.1 76 0 260 0 0 Q7RTR2 2.04e-58 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 26356 XM_044310837.1 76 0 260 0 0 Q7RTR2 2.55e-40 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 26357 XM_044310837.1 76 0 260 0 0 Q7RTR2 1.81e-34 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 26358 XR_003823530.2 12 0 18 0 21 NA NA NA NA NA NA 26359 XM_044321558.1 1788 1074 755 1464 1410 Q01062 0 cGMP-dependent 3',5'-cyclic phosphodiesterase (EC 3.1.4.17) (Cyclic GMP-stimulated phosphodiesterase) (CGS-PDE) (cGSPDE) Rattus norvegicus (Rat) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cardiac septum development [GO:0003279]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; coronary vasculature development [GO:0060976]; establishment of endothelial barrier [GO:0061028]; heart development [GO:0007507]; heart valve development [GO:0003170]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cell death [GO:0060548]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of cGMP-mediated signaling [GO:0010752]; regulation of mitochondrion organization [GO:0010821]; regulation of nitric oxide mediated signal transduction [GO:0010749]; response to hydrogen sulfide [GO:1904880]; signal transduction [GO:0007165]; ventricular septum development [GO:0003281] GO:0000122; GO:0000287; GO:0003170; GO:0003279; GO:0003281; GO:0004114; GO:0004115; GO:0004118; GO:0005634; GO:0005737; GO:0005739; GO:0005741; GO:0005743; GO:0005759; GO:0005783; GO:0005794; GO:0005829; GO:0005886; GO:0007165; GO:0007193; GO:0007507; GO:0008270; GO:0010628; GO:0010749; GO:0010752; GO:0010754; GO:0010821; GO:0019933; GO:0019934; GO:0030424; GO:0030425; GO:0030552; GO:0030553; GO:0030911; GO:0035904; GO:0036004; GO:0036006; GO:0042301; GO:0042734; GO:0042802; GO:0042803; GO:0043116; GO:0043117; GO:0043949; GO:0043951; GO:0045121; GO:0046069; GO:0047555; GO:0048471; GO:0050729; GO:0060548; GO:0060976; GO:0061028; GO:0071222; GO:0071260; GO:0071320; GO:0071321; GO:0071560; GO:0090324; GO:0097011; GO:0097060; GO:0097457; GO:1904613; GO:1904880 26360 XM_044329177.1 293 89 199 190 145 Q9P1Y6 6.21e-23 PHD and RING finger domain-containing protein 1 Homo sapiens (Human) mRNA processing [GO:0006397]; transcription by RNA polymerase II [GO:0006366] GO:0006366; GO:0006397; GO:0016020; GO:0019904; GO:0046872; GO:0070063 26361 XM_044312034.1 17 19 54 3 387 P35061 7.67e-86 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 26362 XM_029337631.2 572 297 413 473 613 Q6TGY8 1.91e-108 ER membrane protein complex subunit 2 (Tetratricopeptide repeat protein 35) (TPR repeat protein 35) Danio rerio (Zebrafish) (Brachydanio rerio) protein insertion into ER membrane by stop-transfer membrane-anchor sequence [GO:0045050]; tail-anchored membrane protein insertion into ER membrane [GO:0071816] GO:0005737; GO:0005783; GO:0005789; GO:0042406; GO:0045050; GO:0071816; GO:0072546 26363 XR_006394219.1 20 0 0 0 168 NA NA NA NA NA NA 26364 XM_029340394.2 133 0 0 0 0 E9QAT4 1.14e-45 Protein transport protein Sec16A (SEC16 homolog A) (p250) Mus musculus (Mouse) autophagy [GO:0006914]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; Golgi to plasma membrane transport [GO:0006893]; protein exit from endoplasmic reticulum [GO:0032527]; protein localization to endoplasmic reticulum exit site [GO:0070973]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; response to endoplasmic reticulum stress [GO:0034976] GO:0000139; GO:0005789; GO:0005829; GO:0006888; GO:0006893; GO:0006914; GO:0007029; GO:0007030; GO:0012507; GO:0031090; GO:0032527; GO:0034976; GO:0048208; GO:0048471; GO:0050821; GO:0070971; GO:0070973; GO:0072659 26365 XM_029352981.2 520 564 482 689 1186 Q920M9 7.3e-165 E3 ubiquitin-protein ligase SIAH1 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase SIAH1) (Seven in absentia homolog 1) (Siah-1) (Siah-1a) Rattus norvegicus (Rat) canonical Wnt signaling pathway [GO:0060070]; cell differentiation [GO:0030154]; male meiosis I [GO:0007141]; neuron apoptotic process [GO:0051402]; positive regulation of apoptotic process [GO:0043065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; post-embryonic development [GO:0009791]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein catabolic process [GO:0030163]; protein destabilization [GO:0031648]; regulation of multicellular organism growth [GO:0040014]; spermatogenesis [GO:0007283]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004842; GO:0005634; GO:0005737; GO:0005769; GO:0005829; GO:0005886; GO:0006511; GO:0007141; GO:0007283; GO:0008022; GO:0008270; GO:0009791; GO:0019005; GO:0030154; GO:0030163; GO:0030877; GO:0031624; GO:0031648; GO:0040014; GO:0042802; GO:0042803; GO:0043065; GO:0043161; GO:0051402; GO:0060070; GO:0061630; GO:0097718; GO:2001244 26366 XM_044316015.1 133 0 11 0 380 NA NA NA NA NA NA 26367 XM_029340138.2 541 392 178 571 457 Q96E11 1.91e-36 Ribosome-recycling factor, mitochondrial (RRF) (Ribosome-releasing factor, mitochondrial) Homo sapiens (Human) ribosome disassembly [GO:0032790]; translation [GO:0006412] GO:0005739; GO:0005759; GO:0006412; GO:0032790; GO:0043023 26368 XM_044320322.1 125 107 64 106 117 Q8VHE6 2.27e-150 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5) Mus musculus (Mouse) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0003777; GO:0005524; GO:0005576; GO:0005737; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 26369 XM_044320322.1 125 107 64 106 117 Q8VHE6 2.27e-150 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5) Mus musculus (Mouse) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0003777; GO:0005524; GO:0005576; GO:0005737; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 26370 XM_029323655.2 864 423 40 787 275 Q04786 5.29e-116 Beta-hexosaminidase (EC 3.2.1.52) (Beta-N-acetylhexosaminidase) (Chitobiase) (N-acetyl-beta-glucosaminidase) Vibrio vulnificus chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272] GO:0000272; GO:0004563; GO:0006032; GO:0030247; GO:0102148 26371 XM_044320125.1 55 2 105 15 217 Q9VBW3 8.36e-52 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 26372 XR_003823702.2 94 80 121 225 133 NA NA NA NA NA NA 26373 XM_044319308.1 391 556 358 983 1017 Q8R4K8 0 Pappalysin-1 (EC 3.4.24.79) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase) (Pregnancy-associated plasma protein A) (PAPP-A) Mus musculus (Mouse) cell surface receptor signaling pathway [GO:0007166]; female pregnancy [GO:0007565]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to dexamethasone [GO:0071548]; response to follicle-stimulating hormone [GO:0032354] GO:0004175; GO:0004222; GO:0005576; GO:0005615; GO:0006508; GO:0007166; GO:0007565; GO:0008237; GO:0030163; GO:0032354; GO:0046872; GO:0071548 26374 XM_044314746.1 249 347 253 308 219 NA NA NA NA NA NA 26375 XM_044321918.1 1152 971 799 1355 1129 NA NA NA NA NA NA 26376 XM_044321944.1 0 0 0 0 40 NA NA NA NA NA NA 26377 XM_044310311.1 19 5 12 9 0 NA NA NA NA NA NA 26378 XM_029352099.2 983 360 377 1467 468 Q6V0K7 4.35e-31 Oncoprotein-induced transcript 3 protein (Liver-specific zona pellucida domain-containing protein) Rattus norvegicus (Rat) urate homeostasis [GO:1903118] GO:0005201; GO:0005509; GO:0005615; GO:0005635; GO:0009986; GO:1903118 26379 XM_029341812.2 235 92 84 411 263 A2AJ88 0 Patatin-like phospholipase domain-containing protein 7 (EC 3.1.1.-) (EC 3.1.1.5) (Neuropathy target esterase-related esterase) (NRE) (NTE-related esterase) Mus musculus (Mouse) phosphatidylcholine catabolic process [GO:0034638] GO:0004622; GO:0005783; GO:0005789; GO:0005811; GO:0034638; GO:0102545 26380 XM_029340479.2 307 240 111 319 228 Q1LXR6 1.59e-159 NA NA NA NA 26381 XM_044327475.1 36 251 60 141 248 Q5DU56 2.18e-44 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 26382 XM_044327475.1 36 251 60 141 248 Q5DU56 3.98e-41 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 26383 XM_044327475.1 36 251 60 141 248 Q5DU56 2.56e-33 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 26384 XM_044327475.1 36 251 60 141 248 Q5DU56 8.45e-31 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 26385 XM_044327475.1 36 251 60 141 248 Q5DU56 2.33e-29 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 26386 XM_044323972.1 1 168 85 43 262 NA NA NA NA NA NA 26387 XM_029343032.2 229 368 153 423 376 NA NA NA NA NA NA 26388 XR_006395331.1 9 2 9 0 0 NA NA NA NA NA NA 26389 XM_044320917.1 14 1 48 37 86 Q9VBW3 6.14e-55 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 26390 XM_029337207.2 2 67 0 1 1 Q64731 1.67e-40 Forkhead box protein L1 (Forkhead-related protein FKHL11) (Transcription factor FKH-6) Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; heart development [GO:0007507]; Peyer's patch morphogenesis [GO:0061146]; proteoglycan biosynthetic process [GO:0030166]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of Wnt signaling pathway [GO:0030111]; visceral mesoderm-endoderm interaction involved in midgut development [GO:0007495] GO:0000978; GO:0000981; GO:0003677; GO:0003700; GO:0005634; GO:0006355; GO:0006357; GO:0007495; GO:0007507; GO:0009653; GO:0030111; GO:0030154; GO:0030166; GO:0043565; GO:0061146 26391 XM_029340705.2 109 55 110 177 27 Q3UZD5 1.32e-43 Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.361) (PR domain zinc finger protein 6) (PR domain-containing protein 6) (PR domain-containing protein in smooth muscle) Mus musculus (Mouse) chromatin organization [GO:0006325]; histone methylation [GO:0016571]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of smooth muscle cell differentiation [GO:0051151]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of gene expression [GO:0010468] GO:0000122; GO:0005634; GO:0006325; GO:0010468; GO:0016571; GO:0022008; GO:0042802; GO:0045892; GO:0046872; GO:0051151; GO:0140944 26392 XM_029340705.2 109 55 110 177 27 Q3UZD5 4.82e-40 Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.361) (PR domain zinc finger protein 6) (PR domain-containing protein 6) (PR domain-containing protein in smooth muscle) Mus musculus (Mouse) chromatin organization [GO:0006325]; histone methylation [GO:0016571]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of smooth muscle cell differentiation [GO:0051151]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of gene expression [GO:0010468] GO:0000122; GO:0005634; GO:0006325; GO:0010468; GO:0016571; GO:0022008; GO:0042802; GO:0045892; GO:0046872; GO:0051151; GO:0140944 26393 XM_029340705.2 109 55 110 177 27 Q3UZD5 4.82e-40 Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.361) (PR domain zinc finger protein 6) (PR domain-containing protein 6) (PR domain-containing protein in smooth muscle) Mus musculus (Mouse) chromatin organization [GO:0006325]; histone methylation [GO:0016571]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of smooth muscle cell differentiation [GO:0051151]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of gene expression [GO:0010468] GO:0000122; GO:0005634; GO:0006325; GO:0010468; GO:0016571; GO:0022008; GO:0042802; GO:0045892; GO:0046872; GO:0051151; GO:0140944 26394 XM_044328948.1 25 33 62 34 137 Q9CR92 9.4e-68 Coiled-coil domain-containing protein 96 Mus musculus (Mouse) cilium assembly [GO:0060271] GO:0005930; GO:0036064; GO:0060271 26395 XM_044323625.1 0 0 0 21 11 NA NA NA NA NA NA 26396 XM_029350236.2 16885 18039 9618 19560 8284 Q923S9 3.53e-68 Ras-related protein Rab-30 Mus musculus (Mouse) Golgi organization [GO:0007030]; Rab protein signal transduction [GO:0032482]; vesicle-mediated transport [GO:0016192] GO:0003924; GO:0005525; GO:0005801; GO:0005802; GO:0007030; GO:0016020; GO:0016192; GO:0031985; GO:0032482; GO:0043231 26397 XM_029325391.2 769 500 566 769 737 NA NA NA NA NA NA 26398 XM_044321585.1 33 0 0 4 16 NA NA NA NA NA NA 26399 XM_044321950.1 16 0 0 0 0 NA NA NA NA NA NA 26400 XR_006392642.1 23 5 25 0 35 NA NA NA NA NA NA 26401 XM_044325439.1 874 395 414 558 862 NA NA NA NA NA NA 26402 XM_044309762.1 27 0 26 0 95 NA NA NA NA NA NA 26403 XM_044321113.1 20 0 33 12 26 Q7TN88 5.4e-72 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 26404 XM_044321113.1 20 0 33 12 26 Q7TN88 1.76e-52 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 26405 XM_029325557.2 52 42 14 51 8 NA NA NA NA NA NA 26406 XM_044325998.1 25 10 12 9 7 NA NA NA NA NA NA 26407 XR_006391662.1 24 32 134 24 273 NA NA NA NA NA NA 26408 XM_044323495.1 59 54 42 24 69 Q99728 6.9e-88 BRCA1-associated RING domain protein 1 (BARD-1) (EC 2.3.2.27) (RING-type E3 ubiquitin transferase BARD1) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; cellular response to ionizing radiation [GO:0071479]; DNA repair [GO:0006281]; DNA strand resection involved in replication fork processing [GO:0110025]; histone H2A K63-linked deubiquitination [GO:0070537]; histone H2A monoubiquitination [GO:0035518]; homologous recombination [GO:0035825]; mitotic G2/M transition checkpoint [GO:0044818]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle [GO:0045786]; negative regulation of mRNA 3'-end processing [GO:0031441]; negative regulation of protein export from nucleus [GO:0046826]; positive regulation of apoptotic process [GO:0043065]; positive regulation of protein catabolic process [GO:0045732]; protein autoubiquitination [GO:0051865]; protein K6-linked ubiquitination [GO:0085020]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of cell cycle [GO:0051726]; regulation of DNA damage checkpoint [GO:2000001]; regulation of DNA repair [GO:0006282]; regulation of phosphorylation [GO:0042325]; tissue homeostasis [GO:0001894] GO:0000151; GO:0000152; GO:0000209; GO:0001894; GO:0003723; GO:0004842; GO:0005634; GO:0005654; GO:0005737; GO:0006281; GO:0006282; GO:0006974; GO:0016567; GO:0016607; GO:0019900; GO:0031436; GO:0031441; GO:0035518; GO:0035825; GO:0036464; GO:0042325; GO:0042803; GO:0043065; GO:0043066; GO:0044818; GO:0045732; GO:0045786; GO:0046826; GO:0046872; GO:0046982; GO:0051726; GO:0051865; GO:0070531; GO:0070532; GO:0070533; GO:0070537; GO:0071479; GO:0085020; GO:0110025; GO:2000001 26409 XM_029328282.2 31 0 1 0 47 NA NA NA NA NA NA 26410 XM_044308390.1 6 7 41 2 83 NA NA NA NA NA NA 26411 XM_044324692.1 0 1015 3 5 3 D3YXG0 3.53e-45 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 26412 XM_044324692.1 0 1015 3 5 3 D3YXG0 5.48e-43 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 26413 XM_044324692.1 0 1015 3 5 3 D3YXG0 3.9e-42 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 26414 XM_044324692.1 0 1015 3 5 3 D3YXG0 1.5e-39 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 26415 XM_044324692.1 0 1015 3 5 3 D3YXG0 6.48e-39 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 26416 XM_044324692.1 0 1015 3 5 3 D3YXG0 1.5e-38 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 26417 XM_044324692.1 0 1015 3 5 3 D3YXG0 1.99e-38 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 26418 XM_044324692.1 0 1015 3 5 3 D3YXG0 1.75e-37 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 26419 XM_044324692.1 0 1015 3 5 3 D3YXG0 1.9e-37 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 26420 XM_044324692.1 0 1015 3 5 3 D3YXG0 6.05e-36 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 26421 XM_044324692.1 0 1015 3 5 3 D3YXG0 3.63e-35 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 26422 XM_044324692.1 0 1015 3 5 3 D3YXG0 7.72e-35 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 26423 XM_044324692.1 0 1015 3 5 3 D3YXG0 4.71e-34 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 26424 XM_044324692.1 0 1015 3 5 3 D3YXG0 5.21e-25 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 26425 XM_044309349.1 15 6 0 4 71 NA NA NA NA NA NA 26426 XM_044310964.1 129 34 62 55 85 P08419 4.99e-49 Chymotrypsin-like elastase family member 2A (EC 3.4.21.71) (Elastase-2) (Elastase-2A) Sus scrofa (Pig) insulin catabolic process [GO:1901143]; proteolysis [GO:0006508]; regulation of insulin secretion [GO:0050796]; regulation of platelet aggregation [GO:0090330]; response to insulin [GO:0032868] GO:0004175; GO:0004252; GO:0005576; GO:0005615; GO:0006508; GO:0032868; GO:0050796; GO:0090330; GO:1901143 26427 XM_044310964.1 129 34 62 55 85 P08419 1.98e-33 Chymotrypsin-like elastase family member 2A (EC 3.4.21.71) (Elastase-2) (Elastase-2A) Sus scrofa (Pig) insulin catabolic process [GO:1901143]; proteolysis [GO:0006508]; regulation of insulin secretion [GO:0050796]; regulation of platelet aggregation [GO:0090330]; response to insulin [GO:0032868] GO:0004175; GO:0004252; GO:0005576; GO:0005615; GO:0006508; GO:0032868; GO:0050796; GO:0090330; GO:1901143 26428 XM_029349999.2 24 0 0 0 24 NA NA NA NA NA NA 26429 XM_029347080.2 15 28 18 9 57 NA NA NA NA NA NA 26430 XM_044328013.1 49 0 32 82 59 Q96DB5 1.72e-69 Regulator of microtubule dynamics protein 1 (RMD-1) (hRMD-1) (Protein FAM82B) Homo sapiens (Human) attachment of mitotic spindle microtubules to kinetochore [GO:0051315]; mitotic spindle organization [GO:0007052] GO:0005737; GO:0005876; GO:0007052; GO:0008017; GO:0051315; GO:0097431 26431 XM_044308574.1 8239 4466 4153 9372 6600 Q9JHU4 0 Cytoplasmic dynein 1 heavy chain 1 (Cytoplasmic dynein heavy chain 1) (Dynein heavy chain, cytosolic) Mus musculus (Mouse) cell division [GO:0051301]; cilium movement [GO:0003341]; cytoplasmic microtubule organization [GO:0031122]; establishment of spindle localization [GO:0051293]; microtubule-based movement [GO:0007018]; minus-end-directed vesicle transport along microtubule [GO:0072382]; mitotic cell cycle [GO:0000278]; nuclear migration [GO:0007097]; P-body assembly [GO:0033962]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of intracellular transport [GO:0032388]; positive regulation of spindle assembly [GO:1905832]; regulation of metaphase plate congression [GO:0090235]; regulation of mitotic spindle organization [GO:0060236]; retrograde axonal transport [GO:0008090]; stress granule assembly [GO:0034063] GO:0000278; GO:0002177; GO:0003341; GO:0005524; GO:0005635; GO:0005737; GO:0005813; GO:0005868; GO:0005874; GO:0005881; GO:0005938; GO:0007018; GO:0007097; GO:0008090; GO:0008569; GO:0030175; GO:0030286; GO:0030424; GO:0031122; GO:0032388; GO:0033962; GO:0034063; GO:0043025; GO:0045505; GO:0051293; GO:0051301; GO:0051959; GO:0060236; GO:0072382; GO:0090235; GO:0120162; GO:1904115; GO:1905832 26432 XM_044319548.1 0 0 189 16 266 NA NA NA NA NA NA 26433 XR_003827314.2 27 1 2 3 108 NA NA NA NA NA NA 26434 XM_029332367.2 885 1426 562 656 800 Q9NQP4 6.93e-49 Prefoldin subunit 4 (Protein C-1) Homo sapiens (Human) negative regulation of amyloid fibril formation [GO:1905907]; protein folding [GO:0006457]; protein stabilization [GO:0050821] GO:0001540; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0006457; GO:0016272; GO:0050821; GO:0051082; GO:0051087; GO:1905907 26435 XR_006393752.1 0 0 0 19 0 NA NA NA NA NA NA 26436 XM_029341140.2 31 50 76 70 14 NA NA NA NA NA NA 26437 XM_029343866.2 294 604 92 392 278 NA NA NA NA NA NA 26438 XM_044318598.1 4219 4558 3505 2742 2153 NA NA NA NA NA NA 26439 XM_029334345.2 0 26 0 0 0 E9PUQ8 0 Diacylglycerol kinase delta (DAG kinase delta) (EC 2.7.1.107) Mus musculus (Mouse) diacylglycerol metabolic process [GO:0046339]; endocytosis [GO:0006897]; intracellular signal transduction [GO:0035556]; lipid phosphorylation [GO:0046834]; negative regulation of protein kinase C signaling [GO:0090038]; phosphatidic acid biosynthetic process [GO:0006654]; positive regulation of clathrin-dependent endocytosis [GO:2000370]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; protein transport [GO:0015031]; response to organic substance [GO:0010033] GO:0004143; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0005905; GO:0006654; GO:0006897; GO:0007205; GO:0010033; GO:0015031; GO:0019900; GO:0031410; GO:0035556; GO:0042802; GO:0042803; GO:0045742; GO:0046339; GO:0046834; GO:0046872; GO:0046982; GO:0090038; GO:2000370 26440 XM_044319378.1 9 0 0 0 0 NA NA NA NA NA NA 26441 XM_029345626.2 31 129 84 31 36 NA NA NA NA NA NA 26442 XM_029336713.2 4 0 24 0 32 NA NA NA NA NA NA 26443 XM_029352552.2 985 592 356 679 735 A1L209 4.96e-54 Ataxin-7-like protein 3 (SAGA-associated factor 11 homolog) Danio rerio (Zebrafish) (Brachydanio rerio) chromatin organization [GO:0006325]; histone deubiquitination [GO:0016578]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000124; GO:0003713; GO:0006325; GO:0006357; GO:0008270; GO:0016578; GO:0045893; GO:0071819 26444 XM_029348809.2 95 40 19 57 69 Q32PP9 1.31e-48 Transcription factor Sox-14 Danio rerio (Zebrafish) (Brachydanio rerio) anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; hypothalamus development [GO:0021854]; regulation of DNA-templated transcription [GO:0006355] GO:0000978; GO:0000981; GO:0005634; GO:0006355; GO:0009653; GO:0021854; GO:0030154 26445 XR_006397061.1 109 151 86 81 56 NA NA NA NA NA NA 26446 XM_029358309.2 3 10 0 0 0 Q9QYS2 0 Metabotropic glutamate receptor 3 (mGluR3) Mus musculus (Mouse) G protein-coupled glutamate receptor signaling pathway [GO:0007216]; gene expression [GO:0010467]; modulation of chemical synaptic transmission [GO:0050804]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; regulation of sensory perception of pain [GO:0051930]; regulation of synaptic transmission, glutamatergic [GO:0051966]; sensory perception of pain [GO:0019233]; synaptic transmission, glutamatergic [GO:0035249] GO:0001640; GO:0001641; GO:0005246; GO:0005886; GO:0007216; GO:0010467; GO:0014069; GO:0019233; GO:0030424; GO:0035249; GO:0042734; GO:0043005; GO:0043197; GO:0045211; GO:0048786; GO:0050804; GO:0051930; GO:0051966; GO:0097110; GO:0097449; GO:0098978; GO:0099170 26447 XM_029357101.2 30 97 557 425 316 Q7L0R7 7.74e-31 RING finger protein 44 Homo sapiens (Human) protein ubiquitination [GO:0016567] GO:0016567; GO:0046872; GO:0061630 26448 XM_044313933.1 84 55 122 150 190 NA NA NA NA NA NA 26449 XM_029358570.2 240 0 0 591 200 NA NA NA NA NA NA 26450 XM_029340172.2 590 732 425 790 757 Q9H4G0 2.53e-29 Band 4.1-like protein 1 (Erythrocyte membrane protein band 4.1-like 1) (Neuronal protein 4.1) (4.1N) Homo sapiens (Human) actomyosin structure organization [GO:0031032]; cortical actin cytoskeleton organization [GO:0030866] GO:0003779; GO:0005198; GO:0005829; GO:0005856; GO:0005886; GO:0030866; GO:0031032 26451 XM_029327785.2 54 9 11 0 8 NA NA NA NA NA NA 26452 XM_044327550.1 1003 662 349 743 507 NA NA NA NA NA NA 26453 XM_044319683.1 839 491 537 526 830 P48416 1.91e-91 Cytochrome P450 10 (EC 1.14.-.-) (CYPX) Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004497; GO:0005506; GO:0016705; GO:0020037 26454 XM_029358296.2 167 11 38 15 83 Q9QYS2 0 Metabotropic glutamate receptor 3 (mGluR3) Mus musculus (Mouse) G protein-coupled glutamate receptor signaling pathway [GO:0007216]; gene expression [GO:0010467]; modulation of chemical synaptic transmission [GO:0050804]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; regulation of sensory perception of pain [GO:0051930]; regulation of synaptic transmission, glutamatergic [GO:0051966]; sensory perception of pain [GO:0019233]; synaptic transmission, glutamatergic [GO:0035249] GO:0001640; GO:0001641; GO:0005246; GO:0005886; GO:0007216; GO:0010467; GO:0014069; GO:0019233; GO:0030424; GO:0035249; GO:0042734; GO:0043005; GO:0043197; GO:0045211; GO:0048786; GO:0050804; GO:0051930; GO:0051966; GO:0097110; GO:0097449; GO:0098978; GO:0099170 26455 XM_029344454.2 125 152 107 163 171 Q8N865 9.57e-34 Uncharacterized protein C7orf31 Homo sapiens (Human) NA GO:0005737; GO:0005813 26456 XM_044324357.1 19 144 137 138 390 NA NA NA NA NA NA 26457 XR_003825320.2 130 127 64 127 63 NA NA NA NA NA NA 26458 XM_044318596.1 721 404 632 723 767 Q6NV04 0 2-hydroxyacyl-CoA lyase 2 (EC 4.1.2.-) (Acetolactate synthase-like protein) (IlvB-like protein) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic cranial skeleton morphogenesis [GO:0048701]; fatty acid alpha-oxidation [GO:0001561]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099] GO:0000287; GO:0001561; GO:0003984; GO:0005789; GO:0005948; GO:0009097; GO:0009099; GO:0016829; GO:0030976; GO:0048701; GO:0050660 26459 XM_044311922.1 69 22 24 87 51 NA NA NA NA NA NA 26460 XM_029336629.2 31 47 44 24 100 P19579 3.27e-22 Capsule biosynthesis protein CapA Bacillus anthracis capsule polysaccharide biosynthetic process [GO:0045227] GO:0005886; GO:0045227 26461 XM_044315820.1 4 12 0 26 9 NA NA NA NA NA NA 26462 XM_029357097.2 188 245 63 164 166 Q8WXF0 3.41e-45 Serine/arginine-rich splicing factor 12 (35 kDa SR repressor protein) (SRrp35) (Splicing factor, arginine/serine-rich 13B) (Splicing factor, arginine/serine-rich 19) Homo sapiens (Human) mRNA 5'-splice site recognition [GO:0000395]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; spliceosomal tri-snRNP complex assembly [GO:0000244] GO:0000244; GO:0000381; GO:0000395; GO:0000398; GO:0003723; GO:0005654; GO:0005737; GO:0016607; GO:0048025; GO:0050733; GO:0051082 26463 XM_044319705.1 18 0 0 12 0 Q3SZ21 2.93e-53 Ribonuclease P protein subunit p30 (RNaseP protein p30) (RNase P subunit 2) Bos taurus (Bovine) RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; rRNA processing [GO:0006364]; tRNA 5'-leader removal [GO:0001682]; tRNA processing [GO:0008033] GO:0000172; GO:0001682; GO:0003723; GO:0004526; GO:0005655; GO:0006364; GO:0008033; GO:0033204; GO:0090502 26464 XM_029350758.2 409 1142 578 1906 1490 P51029 7.96e-72 Protein Wnt-8b Danio rerio (Zebrafish) (Brachydanio rerio) canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; commissural neuron axon guidance [GO:0071679]; embryonic pattern specification [GO:0009880]; eye development [GO:0001654]; eye field cell fate commitment involved in camera-type eye formation [GO:0060898]; forebrain development [GO:0030900]; forebrain neuron differentiation [GO:0021879]; hypothalamus development [GO:0021854]; negative regulation of anterior neural cell fate commitment of the neural plate by Wnt signaling pathway [GO:0022002]; neuron differentiation [GO:0030182]; otic placode formation [GO:0043049]; sensory epithelium regeneration [GO:0070654] GO:0001654; GO:0005109; GO:0005125; GO:0005615; GO:0009880; GO:0021854; GO:0021879; GO:0022002; GO:0030182; GO:0030900; GO:0043049; GO:0045165; GO:0060070; GO:0060898; GO:0070654; GO:0071679 26465 XM_029344513.2 395 42 295 2 0 NA NA NA NA NA NA 26466 XM_044319786.1 0 0 31 60 0 Q8R151 2.09e-131 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 26467 XM_044319786.1 0 0 31 60 0 Q8R151 2.08e-79 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 26468 XM_044319786.1 0 0 31 60 0 Q8R151 7.5e-72 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 26469 XM_044319786.1 0 0 31 60 0 Q8R151 9.43e-23 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 26470 XR_003823140.1 2 7 2 9 4 NA NA NA NA NA NA 26471 XM_029331496.2 836 114 526 722 739 O14770 6.47e-114 Homeobox protein Meis2 (Meis1-related protein 1) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; brain development [GO:0007420]; embryonic pattern specification [GO:0009880]; eye development [GO:0001654]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas development [GO:0031016]; positive regulation of cardiac muscle myoblast proliferation [GO:0110024]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; response to growth factor [GO:0070848]; response to mechanical stimulus [GO:0009612]; visual learning [GO:0008542] GO:0000122; GO:0000785; GO:0000978; GO:0000981; GO:0001228; GO:0001654; GO:0003677; GO:0005634; GO:0006357; GO:0007420; GO:0008134; GO:0008284; GO:0008542; GO:0009612; GO:0009880; GO:0009887; GO:0031016; GO:0043565; GO:0045638; GO:0045931; GO:0045944; GO:0048471; GO:0070848; GO:0110024; GO:1990837 26472 XM_044322075.1 714 315 443 220 158 Q8IZH2 0 5'-3' exoribonuclease 1 (EC 3.1.13.-) (Strand-exchange protein 1 homolog) Homo sapiens (Human) cellular response to cycloheximide [GO:0071409]; cellular response to puromycin [GO:1905795]; histone mRNA catabolic process [GO:0071044]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of translation [GO:0017148]; nuclear mRNA surveillance [GO:0071028]; nuclear-transcribed mRNA catabolic process [GO:0000956]; response to testosterone [GO:0033574]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; rRNA catabolic process [GO:0016075] GO:0000932; GO:0000956; GO:0002151; GO:0003723; GO:0004534; GO:0005634; GO:0005829; GO:0005886; GO:0016020; GO:0016075; GO:0017148; GO:0030425; GO:0032211; GO:0033574; GO:0043025; GO:0045202; GO:0051880; GO:0070034; GO:0071028; GO:0071044; GO:0071409; GO:0090503; GO:1905795 26473 XM_029339989.2 1059 952 586 1514 1196 NA NA NA NA NA NA 26474 XR_006394918.1 6 3 0 0 0 NA NA NA NA NA NA 26475 XM_029352267.2 148 137 179 157 149 Q6GR35 1.62e-57 Protein Abitram (Actin-binding transcription modulator) (Protein Simiate) Xenopus laevis (African clawed frog) dendrite morphogenesis [GO:0048813]; regulation of actin filament polymerization [GO:0030833]; regulation of filopodium assembly [GO:0051489] GO:0016607; GO:0030027; GO:0030425; GO:0030426; GO:0030833; GO:0032433; GO:0048813; GO:0051489 26476 XM_029336809.2 4 0 3 4 87 NA NA NA NA NA NA 26477 XM_044320537.1 2366 732 1000 1954 1323 Q6V0I7 0 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 26478 XM_044320537.1 2366 732 1000 1954 1323 Q6V0I7 0 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 26479 XR_006398143.1 2 9 12 8 31 NA NA NA NA NA NA 26480 XR_006398107.1 299 359 21 136 94 NA NA NA NA NA NA 26481 XM_029346151.2 2700 2591 1677 1925 1985 Q6PBM1 3.01e-48 Glutaredoxin-related protein 5, mitochondrial (Monothiol glutaredoxin-5) Danio rerio (Zebrafish) (Brachydanio rerio) hemopoiesis [GO:0030097]; iron-sulfur cluster assembly [GO:0016226] GO:0005737; GO:0005739; GO:0005759; GO:0016226; GO:0030097; GO:0046872; GO:0051537 26482 XM_029358163.2 431 1082 760 968 600 O00628 1.4e-128 Peroxisomal targeting signal 2 receptor (PTS2 receptor) (Peroxin-7) Homo sapiens (Human) endochondral ossification [GO:0001958]; ether lipid biosynthetic process [GO:0008611]; fatty acid beta-oxidation [GO:0006635]; neuron migration [GO:0001764]; peroxisome organization [GO:0007031]; protein import into peroxisome matrix [GO:0016558] GO:0001764; GO:0001958; GO:0005053; GO:0005777; GO:0005778; GO:0005782; GO:0005829; GO:0006635; GO:0007031; GO:0008611; GO:0016558; GO:0019899; GO:0042803 26483 XR_006393937.1 0 180 1 0 39 NA NA NA NA NA NA 26484 XM_044327566.1 52 26 30 140 88 NA NA NA NA NA NA 26485 XM_029358265.2 312 598 245 381 440 Q7TN88 1.11e-59 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 26486 XM_044312783.1 1028 605 439 759 734 Q5U3N0 5.6e-116 Pleckstrin homology domain-containing family A member 8 (PH domain-containing family A member 8) Danio rerio (Zebrafish) (Brachydanio rerio) ceramide transport [GO:0035627]; ER to Golgi ceramide transport [GO:0035621]; intermembrane lipid transfer [GO:0120009]; protein transport [GO:0015031] GO:0005794; GO:0005829; GO:0015031; GO:0016020; GO:0035621; GO:0035627; GO:0120009; GO:1902387; GO:1902388 26487 XM_029348917.2 103 57 4 39 31 NA NA NA NA NA NA 26488 XM_044326655.1 3001 1636 602 6587 2348 B3EWY9 6.9e-23 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 26489 XM_044326655.1 3001 1636 602 6587 2348 B3EWY9 3.91e-21 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 26490 XM_029354868.2 278 185 164 304 361 Q5ZMS6 8.95e-42 Tudor domain-containing protein 3 Gallus gallus (Chicken) chromatin organization [GO:0006325]; mRNA processing [GO:0006397] GO:0003682; GO:0003713; GO:0003723; GO:0005634; GO:0005737; GO:0006325; GO:0006397; GO:0035064 26491 XM_044322502.1 10 0 2 2 48 Q9VBW3 1.02e-61 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 26492 XR_006397436.1 22 4 24 2 138 NA NA NA NA NA NA 26493 XM_044327365.1 964 699 514 1280 638 Q0KL02 3.23e-86 Triple functional domain protein (EC 2.7.11.1) Mus musculus (Mouse) axon guidance [GO:0007411]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of fat cell differentiation [GO:0045599]; neuron projection morphogenesis [GO:0048812]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; protein phosphorylation [GO:0006468] GO:0004674; GO:0005085; GO:0005524; GO:0005737; GO:0005769; GO:0006468; GO:0007411; GO:0019898; GO:0019899; GO:0042995; GO:0045599; GO:0048786; GO:0048812; GO:0050804; GO:0098685; GO:0098794; GO:0098978; GO:0099170; GO:0106310 26494 XM_044327365.1 964 699 514 1280 638 Q0KL02 2.17e-66 Triple functional domain protein (EC 2.7.11.1) Mus musculus (Mouse) axon guidance [GO:0007411]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of fat cell differentiation [GO:0045599]; neuron projection morphogenesis [GO:0048812]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; protein phosphorylation [GO:0006468] GO:0004674; GO:0005085; GO:0005524; GO:0005737; GO:0005769; GO:0006468; GO:0007411; GO:0019898; GO:0019899; GO:0042995; GO:0045599; GO:0048786; GO:0048812; GO:0050804; GO:0098685; GO:0098794; GO:0098978; GO:0099170; GO:0106310 26495 XM_044327365.1 964 699 514 1280 638 Q0KL02 2.98e-53 Triple functional domain protein (EC 2.7.11.1) Mus musculus (Mouse) axon guidance [GO:0007411]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of fat cell differentiation [GO:0045599]; neuron projection morphogenesis [GO:0048812]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; protein phosphorylation [GO:0006468] GO:0004674; GO:0005085; GO:0005524; GO:0005737; GO:0005769; GO:0006468; GO:0007411; GO:0019898; GO:0019899; GO:0042995; GO:0045599; GO:0048786; GO:0048812; GO:0050804; GO:0098685; GO:0098794; GO:0098978; GO:0099170; GO:0106310 26496 XR_006395965.1 57 0 1 11 0 NA NA NA NA NA NA 26497 XM_029357832.2 6453 4881 4231 8321 7313 NA NA NA NA NA NA 26498 XR_006391771.1 392 170 208 544 433 Q9R1I1 8.31e-23 Carbohydrate sulfotransferase 4 (EC 2.8.2.-) (Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 3) (GST-3) (High endothelial cells N-acetylglucosamine 6-O-sulfotransferase) (HEC-GlcNAc6ST) (L-selectin ligand sulfotransferase) (LSST) (N-acetylglucosamine 6-O-sulfotransferase 2) (GlcNAc6ST-2) (Gn6st-2) Mus musculus (Mouse) carbohydrate metabolic process [GO:0005975]; inflammatory response [GO:0006954]; leukocyte tethering or rolling [GO:0050901]; N-acetylglucosamine metabolic process [GO:0006044]; positive regulation of leukocyte tethering or rolling [GO:1903238]; protein sulfation [GO:0006477]; sulfur compound metabolic process [GO:0006790] GO:0000139; GO:0001517; GO:0005802; GO:0005975; GO:0006044; GO:0006477; GO:0006790; GO:0006954; GO:0050901; GO:1903238 26499 XM_044327156.1 461 266 230 407 403 NA NA NA NA NA NA 26500 XM_029338581.2 24 0 0 173 108 Q13976 0 cGMP-dependent protein kinase 1 (cGK 1) (cGK1) (EC 2.7.11.12) (cGMP-dependent protein kinase I) (cGKI) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cGMP-mediated signaling [GO:0019934]; collateral sprouting [GO:0048668]; dendrite development [GO:0016358]; forebrain development [GO:0030900]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; negative regulation of vascular associated smooth muscle cell proliferation [GO:1904706]; neuron migration [GO:0001764]; protein phosphorylation [GO:0006468]; regulation of GTPase activity [GO:0043087]; relaxation of vascular associated smooth muscle [GO:0060087]; signal transduction [GO:0007165] GO:0001764; GO:0004672; GO:0004692; GO:0005246; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005886; GO:0006468; GO:0007165; GO:0016358; GO:0019934; GO:0030036; GO:0030553; GO:0030900; GO:0042802; GO:0043087; GO:0048668; GO:0060087; GO:0090331; GO:0106310; GO:1904706; GO:1904753 26501 XM_044322487.1 105 0 0 2 1 NA NA NA NA NA NA 26502 XM_029357078.2 0 126 87 136 177 NA NA NA NA NA NA 26503 XM_029342474.2 368 92 104 253 177 NA NA NA NA NA NA 26504 XM_044321641.1 37 12 52 7 78 NA NA NA NA NA NA 26505 XM_044321956.1 967 6 281 526 760 NA NA NA NA NA NA 26506 XM_044307649.1 1077 624 457 1095 748 Q03146 2.68e-100 Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (Protein-tyrosine kinase MPK-6) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a) Mus musculus (Mouse) axon development [GO:0061564]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell population proliferation [GO:0008283]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; ear development [GO:0043583]; embryo implantation [GO:0007566]; lactation [GO:0007595]; mammary gland alveolus development [GO:0060749]; negative regulation of cell population proliferation [GO:0008285]; neuron projection extension [GO:1990138]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of kinase activity [GO:0033674]; protein autophosphorylation [GO:0046777]; regulation of cell growth [GO:0001558]; regulation of cell-matrix adhesion [GO:0001952]; regulation of extracellular matrix disassembly [GO:0010715]; smooth muscle cell migration [GO:0014909]; smooth muscle cell-matrix adhesion [GO:0061302]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing, spreading of cells [GO:0044319] GO:0001558; GO:0001952; GO:0004714; GO:0005518; GO:0005524; GO:0005737; GO:0005886; GO:0005903; GO:0007169; GO:0007566; GO:0007595; GO:0008283; GO:0008285; GO:0010715; GO:0014909; GO:0016323; GO:0018108; GO:0033674; GO:0038062; GO:0038063; GO:0038083; GO:0043235; GO:0043583; GO:0044319; GO:0046777; GO:0046872; GO:0060444; GO:0060749; GO:0061302; GO:0061564; GO:1990138 26507 XM_044307649.1 1077 624 457 1095 748 Q03146 1.07e-24 Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (Protein-tyrosine kinase MPK-6) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a) Mus musculus (Mouse) axon development [GO:0061564]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell population proliferation [GO:0008283]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; ear development [GO:0043583]; embryo implantation [GO:0007566]; lactation [GO:0007595]; mammary gland alveolus development [GO:0060749]; negative regulation of cell population proliferation [GO:0008285]; neuron projection extension [GO:1990138]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of kinase activity [GO:0033674]; protein autophosphorylation [GO:0046777]; regulation of cell growth [GO:0001558]; regulation of cell-matrix adhesion [GO:0001952]; regulation of extracellular matrix disassembly [GO:0010715]; smooth muscle cell migration [GO:0014909]; smooth muscle cell-matrix adhesion [GO:0061302]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing, spreading of cells [GO:0044319] GO:0001558; GO:0001952; GO:0004714; GO:0005518; GO:0005524; GO:0005737; GO:0005886; GO:0005903; GO:0007169; GO:0007566; GO:0007595; GO:0008283; GO:0008285; GO:0010715; GO:0014909; GO:0016323; GO:0018108; GO:0033674; GO:0038062; GO:0038063; GO:0038083; GO:0043235; GO:0043583; GO:0044319; GO:0046777; GO:0046872; GO:0060444; GO:0060749; GO:0061302; GO:0061564; GO:1990138 26508 XM_044319726.1 1366 1244 605 1256 1488 A7MBL8 0 Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like 2) (Protein-kinase C-related kinase 2) Danio rerio (Zebrafish) (Brachydanio rerio) cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell division [GO:0051301]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105] GO:0004674; GO:0004698; GO:0005524; GO:0005634; GO:0005737; GO:0005856; GO:0007049; GO:0007155; GO:0018105; GO:0030027; GO:0030496; GO:0031267; GO:0032154; GO:0035556; GO:0051301; GO:0070161; GO:0106310 26509 XM_044318165.1 142 0 0 0 0 Q28GQ2 8e-102 Enoyl-[acyl-carrier-protein] reductase, mitochondrial (EC 1.3.1.104) (2-enoyl thioester reductase) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) fatty acid biosynthetic process [GO:0006633]; pronephric nephron tubule development [GO:0039020] GO:0005739; GO:0006633; GO:0016491; GO:0039020 26510 XM_044311951.1 16 1 8 110 36 NA NA NA NA NA NA 26511 XM_044307105.1 1804 1816 1218 1202 1254 Q9UI43 6.71e-56 rRNA methyltransferase 2, mitochondrial (EC 2.1.1.-) (16S rRNA (uridine(1369)-2'-O)-methyltransferase) (16S rRNA [Um1369] 2'-O-methyltransferase) (Protein ftsJ homolog 2) Homo sapiens (Human) mitochondrial large ribosomal subunit assembly [GO:1902775]; RNA methylation [GO:0001510]; rRNA 2'-O-methylation [GO:0000451]; rRNA methylation [GO:0031167]; rRNA processing [GO:0006364] GO:0000451; GO:0001510; GO:0005730; GO:0005739; GO:0005759; GO:0006364; GO:0008173; GO:0008650; GO:0031167; GO:1902775 26512 XR_006397419.1 3 8 48 21 16 NA NA NA NA NA NA 26513 XM_044322808.1 0 136 20 96 19 Q13591 1.15e-71 Semaphorin-5A (Semaphorin-F) (Sema F) Homo sapiens (Human) axon extension [GO:0048675]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell-cell signaling [GO:0007267]; diencephalon development [GO:0021536]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of cell adhesion [GO:0007162]; negative regulation of endothelial cell apoptotic process [GO:2000352]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; positive chemotaxis [GO:0050918]; positive regulation of actin filament depolymerization [GO:0030836]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein kinase B signaling [GO:0051897]; semaphorin-plexin signaling pathway [GO:0071526]; signal clustering [GO:1990256] GO:0001755; GO:0001938; GO:0002043; GO:0005886; GO:0007155; GO:0007162; GO:0007267; GO:0007399; GO:0007411; GO:0007413; GO:0016020; GO:0021536; GO:0030215; GO:0030335; GO:0030836; GO:0035373; GO:0043395; GO:0045499; GO:0045545; GO:0045766; GO:0048675; GO:0048842; GO:0048843; GO:0050918; GO:0051897; GO:0060326; GO:0070062; GO:0071526; GO:0090263; GO:1990256; GO:2000352; GO:2001028 26514 XM_044318900.1 1367 959 733 1146 533 NA NA NA NA NA NA 26515 XM_029353045.2 3900 4071 3548 2688 4862 Q6IQE0 8.47e-130 Poly(U)-binding-splicing factor PUF60-B Danio rerio (Zebrafish) (Brachydanio rerio) alternative mRNA splicing, via spliceosome [GO:0000380]; apoptotic process [GO:0006915]; mRNA splice site selection [GO:0006376]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381] GO:0000380; GO:0000381; GO:0003677; GO:0003723; GO:0005634; GO:0006376; GO:0006915; GO:1990904 26516 XM_044328923.1 33 0 18 43 80 NA NA NA NA NA NA 26517 XM_044328278.1 717 1475 359 276 78 NA NA NA NA NA NA 26518 XM_029333678.2 2923 2058 1645 2985 2751 Q0IHF9 2.21e-45 Store-operated calcium entry-associated regulatory factor (SARAF) (SOCE-associated regulatory factor) (Transmembrane protein 66) Xenopus laevis (African clawed frog) calcium ion transport [GO:0006816]; regulation of store-operated calcium entry [GO:2001256] GO:0005789; GO:0006816; GO:0140268; GO:2001256 26519 XM_029335530.2 539 425 323 1196 679 Q9BRP7 4.08e-36 Ferredoxin-fold anticodon-binding domain-containing protein 1 (FDX-ACDB domain-containing protein 1) Homo sapiens (Human) rRNA base methylation [GO:0070475] GO:0005737; GO:0070042; GO:0070475 26520 XR_006394146.1 24 0 22 9 10 NA NA NA NA NA NA 26521 XM_029326455.2 24 15 19 21 41 Q09575 2.61e-28 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 26522 XM_044328173.1 536 1205 553 464 411 NA NA NA NA NA NA 26523 XR_006392905.1 41 2 25 5 151 NA NA NA NA NA NA 26524 XM_044313803.1 1 9 0 5 1 P0CT40 2.91e-67 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 26525 XM_029333997.2 20 26 1 27 0 NA NA NA NA NA NA 26526 XR_006392694.1 29 0 0 0 0 NA NA NA NA NA NA 26527 XM_029351089.2 0 111 0 0 29 NA NA NA NA NA NA 26528 XM_029352453.2 126 337 153 337 252 Q6IMK3 7.28e-127 DnaJ homolog subfamily C member 27 (Rab and DnaJ domain-containing protein) Danio rerio (Zebrafish) (Brachydanio rerio) intracellular protein transport [GO:0006886] GO:0003924; GO:0005525; GO:0005634; GO:0006886 26529 XM_044314459.1 1371 1430 277 237 1555 NA NA NA NA NA NA 26530 XM_029332584.2 247 92 405 313 437 Q5R7Q3 6.01e-127 Magnesium transporter NIPA2 (Non-imprinted in Prader-Willi/Angelman syndrome region protein 2 homolog) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0005769; GO:0005886; GO:0015095 26531 XM_029356226.2 110 77 110 145 0 O08528 1.72e-110 Hexokinase-2 (EC 2.7.1.1) (Hexokinase type II) (HK II) Mus musculus (Mouse) apoptotic mitochondrial changes [GO:0008637]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; cellular response to leukemia inhibitory factor [GO:1990830]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]; lactation [GO:0007595]; maintenance of protein location in mitochondrion [GO:0072656]; negative regulation of mitochondrial membrane permeability [GO:0035795]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; positive regulation of angiogenesis [GO:0045766]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; regulation of glucose import [GO:0046324]; response to hypoxia [GO:0001666]; response to ischemia [GO:0002931] GO:0001666; GO:0001678; GO:0002931; GO:0004340; GO:0004396; GO:0005524; GO:0005536; GO:0005739; GO:0005741; GO:0005813; GO:0005829; GO:0005886; GO:0006002; GO:0006006; GO:0006096; GO:0007595; GO:0008637; GO:0008865; GO:0016529; GO:0035795; GO:0043231; GO:0045766; GO:0046324; GO:0046835; GO:0051156; GO:0072655; GO:0072656; GO:1904925; GO:1990830; GO:2000378 26532 XM_029356226.2 110 77 110 145 0 O08528 2.81e-107 Hexokinase-2 (EC 2.7.1.1) (Hexokinase type II) (HK II) Mus musculus (Mouse) apoptotic mitochondrial changes [GO:0008637]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; cellular response to leukemia inhibitory factor [GO:1990830]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]; lactation [GO:0007595]; maintenance of protein location in mitochondrion [GO:0072656]; negative regulation of mitochondrial membrane permeability [GO:0035795]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; positive regulation of angiogenesis [GO:0045766]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; regulation of glucose import [GO:0046324]; response to hypoxia [GO:0001666]; response to ischemia [GO:0002931] GO:0001666; GO:0001678; GO:0002931; GO:0004340; GO:0004396; GO:0005524; GO:0005536; GO:0005739; GO:0005741; GO:0005813; GO:0005829; GO:0005886; GO:0006002; GO:0006006; GO:0006096; GO:0007595; GO:0008637; GO:0008865; GO:0016529; GO:0035795; GO:0043231; GO:0045766; GO:0046324; GO:0046835; GO:0051156; GO:0072655; GO:0072656; GO:1904925; GO:1990830; GO:2000378 26533 XM_044325860.1 80 0 0 17 0 NA NA NA NA NA NA 26534 XR_003827635.1 29 34 56 30 35 NA NA NA NA NA NA 26535 XM_044309564.1 0 1 0 4 15 NA NA NA NA NA NA 26536 XR_003824515.2 39 45 36 30 18 NA NA NA NA NA NA 26537 XM_044309935.1 17 8 0 6 2 NA NA NA NA NA NA 26538 XM_044319749.1 5 0 0 7 4 NA NA NA NA NA NA 26539 XM_029329281.2 95 161 164 427 140 A7S4N4 2.37e-26 Probable serine incorporator Nematostella vectensis (Starlet sea anemone) phospholipid biosynthetic process [GO:0008654] GO:0005789; GO:0008654; GO:0016020 26540 XM_029333351.2 193 217 91 297 287 P22182 9.29e-78 Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) Xenopus laevis (African clawed frog) positive regulation of cell population proliferation [GO:0008284] GO:0005007; GO:0005524; GO:0005634; GO:0005829; GO:0005886; GO:0008284; GO:0031410 26541 XM_029344161.2 3350 913 1271 3554 2310 Q9UQQ1 4.3e-115 Aminopeptidase NAALADL1 (EC 3.4.11.-) (100 kDa ileum brush border membrane protein) (I100) (Ileal dipeptidylpeptidase) (N-acetylated-alpha-linked acidic dipeptidase-like protein) (NAALADase L) Homo sapiens (Human) peptide catabolic process [GO:0043171]; proteolysis [GO:0006508] GO:0004177; GO:0004180; GO:0005509; GO:0006508; GO:0008233; GO:0008237; GO:0008270; GO:0016020; GO:0016324; GO:0042803; GO:0043171 26542 XM_044319076.1 5 10 0 2 8 NA NA NA NA NA NA 26543 XM_044310984.1 28 0 0 131 131 Q8CG08 4.06e-35 Collagen triple helix repeat-containing protein 1 Rattus norvegicus (Rat) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005581; GO:0005615; GO:0005737; GO:0016477; GO:0016528; GO:0017147; GO:0031012; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0090090; GO:0090103; GO:0090177 26544 XM_044313309.1 54 8 10 15 17 Q8AV58 3.41e-23 Protein sidekick-1 Gallus gallus (Chicken) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; retina layer formation [GO:0010842]; synapse assembly [GO:0007416] GO:0005886; GO:0007156; GO:0007416; GO:0010842; GO:0042802; GO:0045202 26545 XM_044307633.1 13 0 17 4 9 Q0V8S9 1.45e-22 Contactin-associated protein-like 5 (Cell recognition molecule Caspr5) Gallus gallus (Chicken) cell adhesion [GO:0007155] GO:0007155; GO:0016020 26546 XM_029356984.2 9 0 47 4 33 Q924H0 2.85e-32 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide NPFF receptor) Mus musculus (Mouse) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 26547 XM_029337184.2 679 555 206 553 492 NA NA NA NA NA NA 26548 XM_044327705.1 0 0 0 0 126 NA NA NA NA NA NA 26549 XM_044312779.1 14 0 96 160 58 NA NA NA NA NA NA 26550 XM_044325991.1 515 674 473 748 695 NA NA NA NA NA NA 26551 XM_029333736.2 267 409 170 897 956 Q6RT24 1.45e-59 Centromere-associated protein E (Centromere protein E) (CENP-E) (Kinesin superfamily protein 10) (KIF10) (Motor domain of KIF10) Mus musculus (Mouse) attachment of mitotic spindle microtubules to kinetochore [GO:0051315]; attachment of spindle microtubules to kinetochore [GO:0008608]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; establishment of protein localization [GO:0045184]; kinetochore assembly [GO:0051382]; lateral attachment of mitotic spindle microtubules to kinetochore [GO:0099607]; metaphase plate congression [GO:0051310]; microtubule plus-end directed mitotic chromosome migration [GO:0099606]; microtubule-based movement [GO:0007018]; mitotic cell cycle [GO:0000278]; mitotic chromosome movement towards spindle pole [GO:0007079]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly checkpoint signaling [GO:0007094]; mitotic spindle organization [GO:0007052]; positive regulation of attachment of spindle microtubules to kinetochore [GO:0051987]; positive regulation of chromosome segregation [GO:0051984]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; positive regulation of protein kinase activity [GO:0045860]; regulation of developmental process [GO:0050793]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of mitotic nuclear division [GO:0007088]; regulation of protein stability [GO:0031647]; spindle assembly involved in female meiosis I [GO:0007057] GO:0000278; GO:0000775; GO:0000776; GO:0000779; GO:0000940; GO:0003777; GO:0005524; GO:0005634; GO:0005694; GO:0005737; GO:0005828; GO:0005874; GO:0007018; GO:0007052; GO:0007057; GO:0007059; GO:0007079; GO:0007080; GO:0007088; GO:0007094; GO:0008017; GO:0008574; GO:0008608; GO:0015630; GO:0019901; GO:0030071; GO:0030496; GO:0031647; GO:0043231; GO:0043515; GO:0045171; GO:0045184; GO:0045842; GO:0045860; GO:0050793; GO:0051233; GO:0051301; GO:0051310; GO:0051315; GO:0051382; GO:0051984; GO:0051987; GO:0072686; GO:0099606; GO:0099607; GO:1990023 26552 XR_006395804.1 996 531 572 835 485 NA NA NA NA NA NA 26553 XM_044324093.1 4 0 1 0 14 NA NA NA NA NA NA 26554 XM_044309473.1 731 888 479 1068 710 Q91398 2.18e-70 Casein kinase II subunit beta (CK II beta) Danio rerio (Zebrafish) (Brachydanio rerio) regulation of protein serine/threonine phosphatase activity [GO:0080163]; Wnt signaling pathway [GO:0016055] GO:0005737; GO:0005956; GO:0016055; GO:0019887; GO:0046872; GO:0080163 26555 XR_006394132.1 34 0 0 4 74 NA NA NA NA NA NA 26556 XM_044316107.1 0 3 6 0 8 NA NA NA NA NA NA 26557 XM_029352075.2 0 20 5 60 0 NA NA NA NA NA NA 26558 XM_029336896.2 0 74 0 0 0 NA NA NA NA NA NA 26559 XM_044324389.1 188 91 123 155 300 NA NA NA NA NA NA 26560 XM_044313675.1 94 18 60 128 113 NA NA NA NA NA NA 26561 XR_006391914.1 4 15 10 11 13 NA NA NA NA NA NA 26562 XM_029349724.2 58 18 14 36 49 P63079 1.66e-89 Gamma-aminobutyric acid receptor subunit beta-3 (GABA(A) receptor subunit beta-3) Rattus norvegicus (Rat) brain development [GO:0007420]; cellular response to histamine [GO:0071420]; cellular response to zinc ion [GO:0071294]; cerebellum development [GO:0021549]; chemical synaptic transmission [GO:0007268]; chemical synaptic transmission, postsynaptic [GO:0099565]; chloride transmembrane transport [GO:1902476]; circadian sleep/wake cycle, REM sleep [GO:0042747]; cochlea development [GO:0090102]; exploration behavior [GO:0035640]; gamma-aminobutyric acid signaling pathway [GO:0007214]; hard palate development [GO:0060022]; inhibitory postsynaptic potential [GO:0060080]; inhibitory synapse assembly [GO:1904862]; inner ear receptor cell development [GO:0060119]; innervation [GO:0060384]; ion transmembrane transport [GO:0034220]; learning [GO:0007612]; memory [GO:0007613]; motor behavior [GO:0061744]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; nervous system development [GO:0007399]; nervous system process [GO:0050877]; neuron development [GO:0048666]; regulation of membrane potential [GO:0042391]; regulation of neuron apoptotic process [GO:0043523]; regulation of postsynaptic membrane potential [GO:0060078]; reproductive behavior [GO:0019098]; response to anesthetic [GO:0072347]; response to xenobiotic stimulus [GO:0009410]; roof of mouth development [GO:0060021]; sensory perception of sound [GO:0007605]; signal transduction [GO:0007165]; social behavior [GO:0035176]; synaptic transmission, GABAergic [GO:0051932] GO:0004890; GO:0005216; GO:0005231; GO:0005254; GO:0005886; GO:0007165; GO:0007214; GO:0007268; GO:0007399; GO:0007420; GO:0007605; GO:0007612; GO:0007613; GO:0009410; GO:0009986; GO:0019098; GO:0021549; GO:0022851; GO:0030594; GO:0030659; GO:0034220; GO:0034707; GO:0035176; GO:0035612; GO:0035640; GO:0042391; GO:0042747; GO:0042802; GO:0043005; GO:0043195; GO:0043523; GO:0043524; GO:0045202; GO:0045211; GO:0048666; GO:0050877; GO:0051932; GO:0060021; GO:0060022; GO:0060077; GO:0060078; GO:0060080; GO:0060119; GO:0060384; GO:0061744; GO:0071294; GO:0071420; GO:0072347; GO:0090102; GO:0098982; GO:0099565; GO:0099634; GO:1901215; GO:1902476; GO:1902711; GO:1904315; GO:1904862 26563 XM_029324283.2 896 841 1100 1348 984 A8WGS4 8.76e-40 TLC domain-containing protein 2 Danio rerio (Zebrafish) (Brachydanio rerio) lipid homeostasis [GO:0055088]; membrane assembly [GO:0071709]; phospholipid homeostasis [GO:0055091]; plasma membrane organization [GO:0007009]; regulation of membrane lipid distribution [GO:0097035] GO:0005886; GO:0007009; GO:0055088; GO:0055091; GO:0071709; GO:0097035 26564 XR_006393956.1 29 0 43 30 174 NA NA NA NA NA NA 26565 XM_029335502.2 272 238 0 63 129 Q5ZMH1 2.11e-160 Septin-2 Gallus gallus (Chicken) cilium assembly [GO:0060271]; cytoskeleton-dependent cytokinesis [GO:0061640]; regulation of exocytosis [GO:0017157]; smoothened signaling pathway [GO:0007224] GO:0003924; GO:0005525; GO:0005737; GO:0005819; GO:0005940; GO:0007224; GO:0008021; GO:0015630; GO:0017157; GO:0030496; GO:0031105; GO:0032153; GO:0032154; GO:0060090; GO:0060170; GO:0060271; GO:0061640 26566 XM_029351009.2 446 189 201 244 325 Q9VQX4 0 Nicotinate phosphoribosyltransferase (NAPRTase) (EC 6.3.4.21) Drosophila melanogaster (Fruit fly) NAD salvage [GO:0034355]; response to oxidative stress [GO:0006979] GO:0004516; GO:0005829; GO:0006979; GO:0016740; GO:0034355; GO:0046872 26567 XM_044316686.1 129 46 85 264 189 P05183 1.09e-102 Cytochrome P450 3A2 (EC 1.14.14.1) (CYPIIIA2) (Cytochrome P450-PCN2) (Cytochrome P450/6-beta-A) (Testosterone 6-beta-hydroxylase) Rattus norvegicus (Rat) alkaloid catabolic process [GO:0009822]; estrogen metabolic process [GO:0008210]; heterocycle metabolic process [GO:0046483]; lipid hydroxylation [GO:0002933]; monoterpenoid metabolic process [GO:0016098]; oxidative demethylation [GO:0070989]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]; steroid catabolic process [GO:0006706]; steroid metabolic process [GO:0008202]; vitamin D catabolic process [GO:0042369]; xenobiotic catabolic process [GO:0042178]; xenobiotic metabolic process [GO:0006805] GO:0002933; GO:0004497; GO:0005496; GO:0005506; GO:0005737; GO:0005789; GO:0006706; GO:0006805; GO:0008202; GO:0008210; GO:0008395; GO:0008401; GO:0009822; GO:0016098; GO:0016491; GO:0019899; GO:0020037; GO:0030343; GO:0032451; GO:0034875; GO:0042178; GO:0042369; GO:0042572; GO:0042573; GO:0046483; GO:0050649; GO:0062181; GO:0070330; GO:0070576; GO:0070989; GO:0101020; GO:0101021 26568 XM_029352777.2 416 302 266 433 297 NA NA NA NA NA NA 26569 XM_044319285.1 103 38 54 79 14 Q1NZ26 6.84e-30 Uncharacterized protein F13E9.13, mitochondrial Caenorhabditis elegans NA GO:0005739 26570 XR_006397712.1 0 28 8 9 42 NA NA NA NA NA NA 26571 XM_029346069.2 2016 1527 1096 2588 1787 P53451 0 T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta) Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) response to hypoxia [GO:0001666] GO:0001666; GO:0005524; GO:0005737; GO:0016887; GO:0051082; GO:0140662 26572 XM_044309206.1 5 15 3 0 1 NA NA NA NA NA NA 26573 XM_044322598.1 10154 7658 6756 10052 10948 P16086 0 Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) Rattus norvegicus (Rat) actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament capping [GO:0051693] GO:0005509; GO:0005516; GO:0005829; GO:0005886; GO:0005916; GO:0008091; GO:0016020; GO:0016328; GO:0019905; GO:0030018; GO:0030036; GO:0030054; GO:0030507; GO:0030863; GO:0030864; GO:0031532; GO:0032437; GO:0032991; GO:0033010; GO:0033270; GO:0042995; GO:0044877; GO:0051015; GO:0051693; GO:0098794; GO:0098978 26574 XR_003823053.2 5 8 7 12 13 NA NA NA NA NA NA 26575 XM_044311773.1 1209 922 1055 3127 5373 NA NA NA NA NA NA 26576 XM_029344057.2 0 8 0 4 17 NA NA NA NA NA NA 26577 XM_029332350.2 516 419 284 507 275 NA NA NA NA NA NA 26578 XM_029355583.2 197 189 118 129 165 Q5ZIJ9 1.27e-44 E3 ubiquitin-protein ligase MIB2 (EC 2.3.2.27) (Mind bomb homolog 2) (RING-type E3 ubiquitin transferase MIB2) Gallus gallus (Chicken) Notch signaling pathway [GO:0007219]; protein ubiquitination [GO:0016567] GO:0004842; GO:0005737; GO:0007219; GO:0008270; GO:0016567 26579 XM_044313331.1 32 44 63 49 64 NA NA NA NA NA NA 26580 XM_044320805.1 0 0 14 4 0 NA NA NA NA NA NA 26581 XM_029349836.2 663 303 158 650 525 D3YXG0 2.25e-64 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 26582 XM_029349836.2 663 303 158 650 525 D3YXG0 8.84e-46 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 26583 XM_029349836.2 663 303 158 650 525 D3YXG0 8.63e-29 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 26584 XM_044316149.1 45 51 112 30 350 NA NA NA NA NA NA 26585 XM_044309641.1 7 10 0 0 3 NA NA NA NA NA NA 26586 XM_029358719.2 337 170 82 237 475 Q9GYZ0 0 Kinesin-like protein KIF15 (Kinesin-related protein KRP180) Strongylocentrotus purpuratus (Purple sea urchin) microtubule-based movement [GO:0007018]; regulation of mitotic spindle assembly [GO:1901673] GO:0003777; GO:0005524; GO:0005737; GO:0005819; GO:0005871; GO:0005874; GO:0007018; GO:0008017; GO:0016887; GO:1901673 26587 XM_029347594.2 18 115 0 8 41 NA NA NA NA NA NA 26588 XM_044325148.1 0 39 3 2 0 NA NA NA NA NA NA 26589 XM_044320797.1 718 448 356 608 653 Q6NRD3 2.84e-81 E3 ubiquitin-protein ligase SH3RF1 (EC 2.3.2.27) (Plenty of SH3s) (Protein POSH) (xPOSH) (RING-type E3 ubiquitin transferase SH3RF1) (SH3 domain-containing RING finger protein 1) Xenopus laevis (African clawed frog) neuron migration [GO:0001764]; positive regulation of JNK cascade [GO:0046330]; protein autoubiquitination [GO:0051865]; regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043370]; regulation of CD8-positive, alpha-beta T cell proliferation [GO:2000564] GO:0001764; GO:0005078; GO:0005794; GO:0030027; GO:0043370; GO:0046330; GO:0046872; GO:0048471; GO:0051865; GO:0061630; GO:2000564 26590 XM_044320797.1 718 448 356 608 653 Q6NRD3 2.89e-21 E3 ubiquitin-protein ligase SH3RF1 (EC 2.3.2.27) (Plenty of SH3s) (Protein POSH) (xPOSH) (RING-type E3 ubiquitin transferase SH3RF1) (SH3 domain-containing RING finger protein 1) Xenopus laevis (African clawed frog) neuron migration [GO:0001764]; positive regulation of JNK cascade [GO:0046330]; protein autoubiquitination [GO:0051865]; regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043370]; regulation of CD8-positive, alpha-beta T cell proliferation [GO:2000564] GO:0001764; GO:0005078; GO:0005794; GO:0030027; GO:0043370; GO:0046330; GO:0046872; GO:0048471; GO:0051865; GO:0061630; GO:2000564 26591 XM_029358375.2 209 93 71 60 196 Q5SWK7 4.13e-60 RING finger protein 145 (EC 2.3.2.27) Mus musculus (Mouse) NA GO:0005783; GO:0005789; GO:0008270; GO:0012505; GO:0061630 26592 XR_006396205.1 7 3 1 5 6 NA NA NA NA NA NA 26593 XM_044314305.1 59 12 45 49 226 NA NA NA NA NA NA 26594 XM_044321135.1 18 0 0 0 2 NA NA NA NA NA NA 26595 XM_044322523.1 34 0 13 0 15 NA NA NA NA NA NA 26596 XR_003824934.2 124 295 142 284 242 NA NA NA NA NA NA 26597 XR_003828591.2 78 101 53 483 60 NA NA NA NA NA NA 26598 XM_044312059.1 0 0 37 0 8 NA NA NA NA NA NA 26599 XM_029343568.2 1395 202 647 1082 354 Q7LBC6 1.07e-145 Lysine-specific demethylase 3B (EC 1.14.11.65) (JmjC domain-containing histone demethylation protein 2B) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA) ([histone H3]-dimethyl-L-lysine(9) demethylase 3B) Homo sapiens (Human) chromatin organization [GO:0006325]; histone H3-K9 demethylation [GO:0033169]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000118; GO:0000785; GO:0003712; GO:0005654; GO:0006325; GO:0006357; GO:0031490; GO:0032454; GO:0033169; GO:0046872; GO:0140683 26600 XM_029343568.2 1395 202 647 1082 354 Q7LBC6 4.42e-46 Lysine-specific demethylase 3B (EC 1.14.11.65) (JmjC domain-containing histone demethylation protein 2B) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA) ([histone H3]-dimethyl-L-lysine(9) demethylase 3B) Homo sapiens (Human) chromatin organization [GO:0006325]; histone H3-K9 demethylation [GO:0033169]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000118; GO:0000785; GO:0003712; GO:0005654; GO:0006325; GO:0006357; GO:0031490; GO:0032454; GO:0033169; GO:0046872; GO:0140683 26601 XR_003825974.2 12 0 21 31 215 NA NA NA NA NA NA 26602 XM_044312552.1 5 6 6 7 0 NA NA NA NA NA NA 26603 XM_044321198.1 0 0 5 20 0 Q5RHX6 4.43e-87 DCN1-like protein 4 (DCNL4) (DCUN1 domain-containing protein 4) (Defective in cullin neddylation protein 1-like protein 4) Danio rerio (Zebrafish) (Brachydanio rerio) positive regulation of protein neddylation [GO:2000436]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein neddylation [GO:0045116] GO:0000151; GO:0005634; GO:0031624; GO:0032182; GO:0045116; GO:0051443; GO:0097602; GO:2000436 26604 XM_029324135.2 33 426 103 4198 15 NA NA NA NA NA NA 26605 XM_029355822.2 33 12 9 0 37 Q9EQC4 6.71e-66 Elongation of very long chain fatty acids protein 4 (EC 2.3.1.199) (3-keto acyl-CoA synthase Elovl4) (ELOVL fatty acid elongase 4) (ELOVL FA elongase 4) (Very long chain 3-ketoacyl-CoA synthase 4) (Very long chain 3-oxoacyl-CoA synthase 4) Mus musculus (Mouse) fatty acid elongation, monounsaturated fatty acid [GO:0034625]; fatty acid elongation, polyunsaturated fatty acid [GO:0034626]; fatty acid elongation, saturated fatty acid [GO:0019367]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; sphingolipid biosynthetic process [GO:0030148]; unsaturated fatty acid biosynthetic process [GO:0006636]; very long-chain fatty acid biosynthetic process [GO:0042761] GO:0005783; GO:0005789; GO:0006636; GO:0009922; GO:0019367; GO:0030148; GO:0034625; GO:0034626; GO:0035338; GO:0042761; GO:0102756 26606 XM_029333182.2 78 0 55 26 68 Q16281 4.24e-127 Cyclic nucleotide-gated cation channel alpha-3 (Cone photoreceptor cGMP-gated channel subunit alpha) (Cyclic nucleotide-gated channel alpha-3) (CNG channel alpha-3) (CNG-3) (CNG3) Homo sapiens (Human) cation transmembrane transport [GO:0098655]; cation transport [GO:0006812]; inorganic cation import across plasma membrane [GO:0098659]; response to cAMP [GO:0051591]; response to corticosteroid [GO:0031960]; response to magnesium ion [GO:0032026]; signal transduction [GO:0007165]; visual perception [GO:0007601] GO:0005222; GO:0005223; GO:0005737; GO:0005886; GO:0006812; GO:0007165; GO:0007601; GO:0008022; GO:0015276; GO:0017071; GO:0030425; GO:0030553; GO:0031960; GO:0032026; GO:0043194; GO:0043204; GO:0044877; GO:0051591; GO:0097386; GO:0098655; GO:0098659; GO:1902495 26607 XM_044313052.1 24 23 4 135 62 NA NA NA NA NA NA 26608 XM_029356713.2 136 70 30 169 153 NA NA NA NA NA NA 26609 XM_029328538.2 4246 3197 3652 3971 4320 Q5RC80 3.69e-136 RNA-binding protein 39 (RNA-binding motif protein 39) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) mRNA processing [GO:0006397]; regulation of mRNA splicing, via spliceosome [GO:0048024]; RNA splicing [GO:0008380] GO:0003723; GO:0006397; GO:0008380; GO:0016607; GO:0032991; GO:0034451; GO:0048024; GO:0050733 26610 XM_044320737.1 8 3 0 3 2 P0CT39 5.64e-83 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 26611 XM_029341527.1 4 0 3 12 4 Q924H0 4.43e-32 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide NPFF receptor) Mus musculus (Mouse) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 26612 XM_044318067.1 8145 10025 5018 14839 7640 O61463 4.03e-25 60S acidic ribosomal protein P2 Cryptochiton stelleri (Giant gumboot chiton) cytoplasmic translational elongation [GO:0002182] GO:0002182; GO:0003735; GO:0022625 26613 XM_044324064.1 250 126 120 182 169 Q86UB2 2.42e-97 Basic immunoglobulin-like variable motif-containing protein Homo sapiens (Human) NA GO:0005615; GO:0005634; GO:0005737 26614 XM_029345616.2 26 20 30 18 92 NA NA NA NA NA NA 26615 XM_044325085.1 58 0 18 68 130 NA NA NA NA NA NA 26616 XM_044319145.1 887 123 135 503 373 NA NA NA NA NA NA 26617 XM_044323738.1 15 10 6 19 9 NA NA NA NA NA NA 26618 XM_029338670.2 409 460 0 412 1527 Q5F413 4.76e-53 Stromal membrane-associated protein 2 (Stromal membrane-associated protein 1-like) Gallus gallus (Chicken) NA GO:0005096; GO:0005737; GO:0046872 26619 XM_044318671.1 33 10 0 0 0 NA NA NA NA NA NA 26620 XM_044309805.1 11 0 0 0 0 NA NA NA NA NA NA 26621 XM_044321482.1 45 160 133 442 324 Q5I0M0 4.4e-79 Histone-lysine N-methyltransferase SETMAR (EC 2.1.1.357) (SET domain and mariner transposase fusion protein homolog) Rattus norvegicus (Rat) cell population proliferation [GO:0008283]; chromatin organization [GO:0006325]; DNA catabolic process, endonucleolytic [GO:0000737]; DNA double-strand break processing [GO:0000729]; DNA integration [GO:0015074]; double-strand break repair via nonhomologous end joining [GO:0006303]; histone H3-K36 dimethylation [GO:0097676]; histone H3-K36 methylation [GO:0010452]; histone H3-K4 methylation [GO:0051568]; histone methylation [GO:0016571]; mitotic DNA integrity checkpoint signaling [GO:0044774]; negative regulation of chromosome organization [GO:2001251]; negative regulation of DNA-templated transcription [GO:0045892]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity [GO:2000373]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; replication fork processing [GO:0031297] GO:0000014; GO:0000729; GO:0000737; GO:0003677; GO:0003690; GO:0003697; GO:0004519; GO:0005634; GO:0006303; GO:0006325; GO:0008270; GO:0008283; GO:0010452; GO:0015074; GO:0016571; GO:0031297; GO:0035861; GO:0042054; GO:0042800; GO:0042803; GO:0044547; GO:0044774; GO:0045892; GO:0046975; GO:0051568; GO:0090305; GO:0097676; GO:0140954; GO:2000373; GO:2001034; GO:2001251 26622 XM_029342307.2 2228 1345 1211 1718 1974 Q8IW92 7.04e-168 Beta-galactosidase-1-like protein 2 (EC 3.2.1.-) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975] GO:0004565; GO:0005576; GO:0005764; GO:0005773; GO:0005975 26623 XM_044310849.1 146 0 65 29 16 Q99570 5.35e-31 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 26624 XM_044308999.1 0 0 0 0 8 NA NA NA NA NA NA 26625 XR_003825137.2 0 0 0 0 19 O18728 1.79e-113 Fascin-2 (Retinal fascin) Bos taurus (Bovine) actin cytoskeleton organization [GO:0030036]; actin filament bundle assembly [GO:0051017]; cell migration [GO:0016477]; establishment or maintenance of cell polarity [GO:0007163]; eye photoreceptor cell development [GO:0042462] GO:0003779; GO:0005737; GO:0007163; GO:0015629; GO:0016477; GO:0030036; GO:0030674; GO:0032420; GO:0042462; GO:0051015; GO:0051017 26626 XM_029329669.2 132 100 80 193 13 Q26619 1.67e-119 cAMP-dependent protein kinase type II regulatory subunit Strongylocentrotus purpuratus (Purple sea urchin) negative regulation of cAMP-dependent protein kinase activity [GO:2000480] GO:0004862; GO:0005737; GO:0005952; GO:0030552; GO:0034236; GO:2000480 26627 XM_044325645.1 11 0 0 36 23 B8V7S0 9.29e-37 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 26628 XM_029337670.2 133 517 0 575 2 P32674 1.22e-36 Probable dehydratase PflD (EC 4.2.1.-) Escherichia coli (strain K12) NA GO:0005829; GO:0016829 26629 XM_044325826.1 30 14 2 12 4 Q8BR76 6.03e-31 Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67) Mus musculus (Mouse) branching morphogenesis of an epithelial tube [GO:0048754]; cilium assembly [GO:0060271]; determination of left/right symmetry [GO:0007368]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; head development [GO:0060322]; heart development [GO:0007507]; kidney development [GO:0001822]; negative regulation of centrosome duplication [GO:0010826]; non-canonical Wnt signaling pathway [GO:0035567]; photoreceptor cell outer segment organization [GO:0035845]; positive regulation of ERAD pathway [GO:1904294]; positive regulation of non-motile cilium assembly [GO:1902857]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0001822; GO:0005789; GO:0005813; GO:0005886; GO:0005929; GO:0005930; GO:0007368; GO:0007507; GO:0010826; GO:0030433; GO:0030659; GO:0031005; GO:0035567; GO:0035845; GO:0035869; GO:0036038; GO:0048754; GO:0051082; GO:0051787; GO:0060170; GO:0060271; GO:0060322; GO:0060441; GO:1902857; GO:1904294 26630 XM_029337550.2 1575 870 849 1749 1510 NA NA NA NA NA NA 26631 XM_029330053.2 2428 2381 2068 2541 2818 Q14155 4.37e-152 Rho guanine nucleotide exchange factor 7 (Beta-Pix) (COOL-1) (PAK-interacting exchange factor beta) (p85) Homo sapiens (Human) ephrin receptor signaling pathway [GO:0048013]; focal adhesion assembly [GO:0048041]; Golgi organization [GO:0007030]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; negative regulation of microtubule nucleation [GO:1905833]; nervous system development [GO:0007399]; positive regulation of apoptotic process [GO:0043065]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of GTPase activity [GO:0043547]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of GTP binding [GO:1904424]; signal transduction [GO:0007165] GO:0001726; GO:0005085; GO:0005737; GO:0005813; GO:0005829; GO:0005925; GO:0005938; GO:0007030; GO:0007165; GO:0007399; GO:0010763; GO:0019901; GO:0030027; GO:0030032; GO:0032991; GO:0035556; GO:0043005; GO:0043015; GO:0043025; GO:0043065; GO:0043547; GO:0048013; GO:0048041; GO:0097431; GO:0098794; GO:1900026; GO:1904424; GO:1905833; GO:2000394 26632 XM_044314739.1 62 18 109 18 663 P14381 8.87e-59 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 26633 XM_029324473.2 4281 4237 3495 3924 2831 Q14165 9.16e-75 Malectin Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; protein N-linked glycosylation [GO:0006487] GO:0005783; GO:0005789; GO:0005886; GO:0005975; GO:0006487; GO:0008250; GO:0016020; GO:0019899; GO:0030246; GO:0035579 26634 XM_029336695.2 60 185 112 231 207 NA NA NA NA NA NA 26635 XM_029328895.2 616 510 405 462 508 E3TDS3 1.98e-91 Mitochondrial ribosome-associated GTPase 1 (Mitochondrial GTPase 1) Ictalurus punctatus (Channel catfish) (Silurus punctatus) regulation of translation [GO:0006417] GO:0005525; GO:0005743; GO:0005759; GO:0005761; GO:0006417 26636 XM_029357642.2 168 39 90 0 248 P07911 1.3e-22 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Homo sapiens (Human) antibacterial innate immune response [GO:0140367]; apoptotic signaling pathway [GO:0097190]; autophagy [GO:0006914]; cellular calcium ion homeostasis [GO:0006874]; cellular chloride ion homeostasis [GO:0030644]; cellular defense response [GO:0006968]; cellular phosphate ion homeostasis [GO:0030643]; cellular response to unfolded protein [GO:0034620]; cellular sodium ion homeostasis [GO:0006883]; chaperone-mediated protein folding [GO:0061077]; citric acid secretion [GO:0046720]; collecting duct development [GO:0072044]; connective tissue replacement [GO:0097709]; creatinine homeostasis [GO:0097273]; defense response to Gram-negative bacterium [GO:0050829]; endoplasmic reticulum organization [GO:0007029]; glomerular filtration [GO:0003094]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; juxtaglomerular apparatus development [GO:0072051]; leukocyte cell-cell adhesion [GO:0007159]; lipid metabolic process [GO:0006629]; metanephric ascending thin limb development [GO:0072218]; metanephric distal convoluted tubule development [GO:0072221]; metanephric thick ascending limb development [GO:0072233]; micturition [GO:0060073]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell population proliferation [GO:0008285]; neutrophil migration [GO:1990266]; organ or tissue specific immune response [GO:0002251]; peptidyl-threonine phosphorylation [GO:0018107]; potassium ion homeostasis [GO:0055075]; protein localization to vacuole [GO:0072665]; protein transport into plasma membrane raft [GO:0044861]; regulation of blood pressure [GO:0008217]; regulation of protein transport [GO:0051223]; regulation of urine volume [GO:0035809]; renal sodium ion absorption [GO:0070294]; renal urate salt excretion [GO:0097744]; renal water homeostasis [GO:0003091]; response to lipopolysaccharide [GO:0032496]; response to water deprivation [GO:0009414]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; ubiquitin-dependent ERAD pathway [GO:0030433]; urate transport [GO:0015747]; urea transmembrane transport [GO:0071918] GO:0000922; GO:0002251; GO:0003091; GO:0003094; GO:0005201; GO:0005509; GO:0005615; GO:0005783; GO:0005796; GO:0005929; GO:0006629; GO:0006874; GO:0006883; GO:0006914; GO:0006954; GO:0006968; GO:0007029; GO:0007157; GO:0007159; GO:0008217; GO:0008285; GO:0008380; GO:0009410; GO:0009414; GO:0009986; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0018107; GO:0019864; GO:0019898; GO:0030433; GO:0030643; GO:0030644; GO:0032496; GO:0033209; GO:0033555; GO:0034620; GO:0035809; GO:0044861; GO:0046720; GO:0050829; GO:0051223; GO:0055075; GO:0060073; GO:0060170; GO:0061077; GO:0070062; GO:0070294; GO:0071918; GO:0072044; GO:0072051; GO:0072218; GO:0072221; GO:0072233; GO:0072665; GO:0097190; GO:0097273; GO:0097709; GO:0097744; GO:0140367; GO:1990266 26637 XR_006393685.1 0 5 6 1 1 NA NA NA NA NA NA 26638 XR_006393661.1 0 0 0 8 8 NA NA NA NA NA NA 26639 XR_006391720.1 0 0 0 0 8 NA NA NA NA NA NA 26640 XM_044310521.1 138 1 95 14 169 NA NA NA NA NA NA 26641 XR_006394378.1 6 0 0 0 4 NA NA NA NA NA NA 26642 XM_029327103.2 3 7 7 12 33 NA NA NA NA NA NA 26643 XM_029340546.2 9 9 7 10 16 Q5EAB6 0 Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGnT1) (EC 2.4.1.-) Bos taurus (Bovine) O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493] GO:0000139; GO:0006493; GO:0008375; GO:0016020; GO:0016266; GO:0030145 26644 XM_044313917.1 1635 3458 1444 1781 1652 NA NA NA NA NA NA 26645 XM_029332823.2 665 229 312 514 602 Q3U487 1.2e-113 E3 ubiquitin-protein ligase HECTD3 (EC 2.3.2.26) (HECT domain-containing protein 3) (HECT-type E3 ubiquitin transferase HECTD3) Mus musculus (Mouse) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] GO:0004842; GO:0019905; GO:0043161; GO:0048471 26646 XM_029338277.2 25 30 84 50 146 NA NA NA NA NA NA 26647 XM_029327256.2 6 4 17 0 20 A4QNP7 6.93e-29 Doublesex- and mab-3-related transcription factor A2 (Doublesex- and mab-3-related transcription factor 5) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006355; GO:0043565; GO:0046872 26648 XM_044321204.1 474 496 361 457 252 A6H603 2.24e-100 NACHT domain- and WD repeat-containing protein 1 Mus musculus (Mouse) negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of gene expression [GO:0010628] GO:0005524; GO:0005730; GO:0005829; GO:0010628; GO:0032088 26649 XR_006395387.1 4 4 1 6 20 NA NA NA NA NA NA 26650 XM_029335292.2 158 0 32 22 366 NA NA NA NA NA NA 26651 XM_044313256.1 40 81 26 144 115 NA NA NA NA NA NA 26652 XM_029355799.2 4 18 7 0 6 NA NA NA NA NA NA 26653 XR_006397327.1 0 109 0 0 76 NA NA NA NA NA NA 26654 XM_044321137.1 12 1 0 0 1 NA NA NA NA NA NA 26655 XM_029324772.2 0 0 0 575 1 Q9H0Z9 1.23e-32 RNA-binding protein 38 (CLL-associated antigen KW-5) (HSRNASEB) (RNA-binding motif protein 38) (RNA-binding region-containing protein 1) (ssDNA-binding protein SEB4) Homo sapiens (Human) 3'-UTR-mediated mRNA stabilization [GO:0070935]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; mRNA processing [GO:0006397]; mRNA stabilization [GO:0048255]; negative regulation of cell population proliferation [GO:0008285]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of cell cycle [GO:0051726]; regulation of myotube differentiation [GO:0010830]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380] GO:0000381; GO:0003723; GO:0003729; GO:0003730; GO:0005634; GO:0005829; GO:0006397; GO:0006977; GO:0006978; GO:0007049; GO:0008285; GO:0008380; GO:0010830; GO:0030154; GO:0043484; GO:0048255; GO:0051726; GO:0070935 26656 XM_044320238.1 56 43 52 8 126 Q5BKQ4 2.95e-53 Inactive pancreatic lipase-related protein 1 (PL-RP1) Mus musculus (Mouse) lipid metabolic process [GO:0006629] GO:0004806; GO:0005509; GO:0005615; GO:0006629; GO:0016298 26657 XM_029352265.2 387 617 530 861 598 Q96SL4 2.66e-48 Glutathione peroxidase 7 (GPx-7) (GSHPx-7) (EC 1.11.1.9) (CL683) Homo sapiens (Human) cellular response to oxidative stress [GO:0034599] GO:0004096; GO:0004601; GO:0004602; GO:0005576; GO:0005783; GO:0005788; GO:0034599 26658 XR_006396842.1 9 1 11 4 9 NA NA NA NA NA NA 26659 XR_003823971.2 106 50 0 0 0 NA NA NA NA NA NA 26660 XM_029354189.2 1791 1439 1013 1956 2101 Q93009 0 Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7) Homo sapiens (Human) histone H2B conserved C-terminal lysine deubiquitination [GO:0035616]; maintenance of DNA methylation [GO:0010216]; monoubiquitinated protein deubiquitination [GO:0035520]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; positive regulation of DNA demethylation [GO:1901537]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of circadian rhythm [GO:0042752]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of gluconeogenesis [GO:0006111]; regulation of protein stability [GO:0031647]; regulation of retrograde transport, endosome to Golgi [GO:1905279]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of telomere capping [GO:1904353]; rhythmic process [GO:0048511]; transcription-coupled nucleotide-excision repair [GO:0006283]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0002039; GO:0004197; GO:0004843; GO:0005634; GO:0005654; GO:0005694; GO:0005829; GO:0006111; GO:0006283; GO:0006511; GO:0008022; GO:0010216; GO:0016567; GO:0016579; GO:0016604; GO:0016605; GO:0031625; GO:0031647; GO:0032088; GO:0032435; GO:0032991; GO:0035520; GO:0035616; GO:0042752; GO:0048511; GO:0050821; GO:0051090; GO:0101005; GO:1901537; GO:1901796; GO:1904353; GO:1905279; GO:1990380 26661 XM_044310700.1 0 0 9 0 0 NA NA NA NA NA NA 26662 XM_029340879.2 204 69 21 210 122 Q66IV6 3.44e-62 Charged multivesicular body protein 2b-B (Chromatin-modifying protein 2b-B) (CHMP2b-B) Xenopus laevis (African clawed frog) protein transport [GO:0015031]; vacuolar transport [GO:0007034] GO:0005829; GO:0007034; GO:0015031; GO:0031902 26663 XM_029338963.2 190 134 72 89 128 P10079 9.44e-93 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 26664 XM_029338963.2 190 134 72 89 128 P10079 1.09e-86 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 26665 XM_029338963.2 190 134 72 89 128 P10079 3.33e-83 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 26666 XM_029338963.2 190 134 72 89 128 P10079 8.87e-81 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 26667 XM_029338963.2 190 134 72 89 128 P10079 9.6e-47 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 26668 XR_003823217.2 0 16 0 0 0 NA NA NA NA NA NA 26669 XM_044306818.1 440 286 337 1076 909 P98070 5.82e-21 Bone morphogenetic protein 1 (BMP-1) (EC 3.4.24.-) Xenopus laevis (African clawed frog) cartilage development [GO:0051216]; cell differentiation [GO:0030154]; ossification [GO:0001503]; proteolysis [GO:0006508] GO:0001503; GO:0004222; GO:0005125; GO:0005509; GO:0005615; GO:0005794; GO:0006508; GO:0008083; GO:0008270; GO:0030154; GO:0051216 26670 XM_044307140.1 20 0 6 82 6 NA NA NA NA NA NA 26671 XM_044316826.1 367 50 97 235 501 NA NA NA NA NA NA 26672 XM_029347095.2 0 0 0 39 0 NA NA NA NA NA NA 26673 XM_044323141.1 69 0 0 1 4 NA NA NA NA NA NA 26674 XR_003823271.1 2 1 12 2 23 NA NA NA NA NA NA 26675 XM_029356708.2 217 0 79 132 211 Q9DG67 0 DNA repair and recombination protein RAD54B (EC 3.6.4.-) (RAD54 homolog B) Gallus gallus (Chicken) DNA repair [GO:0006281] GO:0003677; GO:0004386; GO:0005524; GO:0005634; GO:0006281; GO:0016787; GO:0140658 26676 XM_029357096.2 1949 1692 1293 2712 2611 Q8WXF0 3.5e-45 Serine/arginine-rich splicing factor 12 (35 kDa SR repressor protein) (SRrp35) (Splicing factor, arginine/serine-rich 13B) (Splicing factor, arginine/serine-rich 19) Homo sapiens (Human) mRNA 5'-splice site recognition [GO:0000395]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; spliceosomal tri-snRNP complex assembly [GO:0000244] GO:0000244; GO:0000381; GO:0000395; GO:0000398; GO:0003723; GO:0005654; GO:0005737; GO:0016607; GO:0048025; GO:0050733; GO:0051082 26677 XM_044324927.1 205 154 102 308 145 P29693 2.95e-45 Elongation factor 1-delta (EF-1-delta) (P36) Xenopus laevis (African clawed frog) NA GO:0003746; GO:0005853 26678 XM_029341070.2 761 730 427 757 1211 NA NA NA NA NA NA 26679 XM_044316283.1 27 8 0 1 22 NA NA NA NA NA NA 26680 XM_029356906.2 79 171 67 79 164 NA NA NA NA NA NA 26681 XM_044322560.1 49 33 0 31 0 NA NA NA NA NA NA 26682 XR_006392397.1 8 0 23 12 0 NA NA NA NA NA NA 26683 XM_044324163.1 1005 751 655 1094 668 Q2VLG6 4.48e-24 Scavenger receptor cysteine-rich type 1 protein M130 (CD antigen CD163) [Cleaved into: Soluble CD163 (sCD163)] Canis lupus familiaris (Dog) (Canis familiaris) acute-phase response [GO:0006953] GO:0005044; GO:0005576; GO:0006953; GO:0009897 26684 XM_029338100.2 3592 3426 2512 4042 3034 O14974 6.42e-80 Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit) Homo sapiens (Human) cellular response to xenobiotic stimulus [GO:0071466]; centrosome cycle [GO:0007098]; mitotic cell cycle [GO:0000278]; negative regulation of catalytic activity [GO:0043086]; positive regulation of myosin-light-chain-phosphatase activity [GO:0035508]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of myosin-light-chain-phosphatase activity [GO:0035507]; regulation of nucleocytoplasmic transport [GO:0046822]; signal transduction [GO:0007165] GO:0000278; GO:0000776; GO:0004857; GO:0005654; GO:0005730; GO:0005737; GO:0005813; GO:0005829; GO:0005886; GO:0005925; GO:0006470; GO:0007098; GO:0007165; GO:0015629; GO:0019208; GO:0019901; GO:0030018; GO:0030155; GO:0031672; GO:0035507; GO:0035508; GO:0043086; GO:0043292; GO:0045944; GO:0046822; GO:0071466; GO:0071889; GO:0072357 26685 XR_006395614.1 43 4 11 11 0 Q20191 5.92e-51 Zinc metalloproteinase nas-13 (EC 3.4.24.-) (Nematode astacin 13) Caenorhabditis elegans proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0006508; GO:0008270 26686 XR_006397498.1 32 0 104 40 21 NA NA NA NA NA NA 26687 XM_044312541.1 114 127 65 88 6 NA NA NA NA NA NA 26688 XR_006395500.1 6 11 2 7 0 NA NA NA NA NA NA 26689 XM_044309698.1 118 48 78 203 243 NA NA NA NA NA NA 26690 XM_044307217.1 0 0 0 0 7493 NA NA NA NA NA NA 26691 XM_029330968.2 165 117 83 167 296 P50336 2.95e-130 Protoporphyrinogen oxidase (PPO) (EC 1.3.3.4) Homo sapiens (Human) heme biosynthetic process [GO:0006783]; porphyrin-containing compound biosynthetic process [GO:0006779]; protoporphyrinogen IX biosynthetic process [GO:0006782] GO:0004729; GO:0005743; GO:0005758; GO:0006779; GO:0006782; GO:0006783; GO:0016491; GO:0031966; GO:0050660 26692 XR_006395306.1 823 929 556 867 530 NA NA NA NA NA NA 26693 XM_029348885.2 760 777 346 526 733 NA NA NA NA NA NA 26694 XR_006397353.1 27 7 0 0 5 NA NA NA NA NA NA 26695 XR_003823459.2 721 1173 1049 712 520 NA NA NA NA NA NA 26696 XM_029329668.2 956 657 368 597 494 Q26619 4.57e-132 cAMP-dependent protein kinase type II regulatory subunit Strongylocentrotus purpuratus (Purple sea urchin) negative regulation of cAMP-dependent protein kinase activity [GO:2000480] GO:0004862; GO:0005737; GO:0005952; GO:0030552; GO:0034236; GO:2000480 26697 XM_044317685.1 71 163 0 103 129 NA NA NA NA NA NA 26698 XM_044315731.1 112 5 58 3 480 NA NA NA NA NA NA 26699 XM_029327152.2 2747 2690 2086 2306 2305 A1L252 0 Ran-binding protein 9 (RanBP9) Danio rerio (Zebrafish) (Brachydanio rerio) cell surface receptor signaling pathway [GO:0007166]; cytoskeleton organization [GO:0007010]; retina development in camera-type eye [GO:0060041] GO:0005634; GO:0005737; GO:0005886; GO:0007010; GO:0007166; GO:0060041 26700 XR_006397263.1 61 34 63 97 167 NA NA NA NA NA NA 26701 XM_044316177.1 81 54 0 0 0 NA NA NA NA NA NA 26702 XM_029355625.2 52 6 36 29 51 Q61184 4.65e-27 Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor) Mus musculus (Mouse) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; circadian rhythm [GO:0007623]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of insulin secretion [GO:0046676] GO:0004930; GO:0005886; GO:0007186; GO:0007193; GO:0007623; GO:0008502; GO:0042562; GO:0043025; GO:0043235; GO:0046676; GO:0097159 26703 XM_029350358.2 219 189 497 717 1226 NA NA NA NA NA NA 26704 XM_044319891.1 189 71 121 222 184 NA NA NA NA NA NA 26705 XM_044317372.1 347 171 104 290 232 NA NA NA NA NA NA 26706 XM_029327034.2 376 110 93 110 122 Q01664 2.48e-29 Transcription factor AP-4 (Activating enhancer-binding protein 4) (Class C basic helix-loop-helix protein 41) (bHLHc41) Homo sapiens (Human) cellular response to dexamethasone stimulus [GO:0071549]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of DNA-templated transcription [GO:0045893]; protein-containing complex assembly [GO:0065003]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000785; GO:0000976; GO:0000978; GO:0000981; GO:0001228; GO:0003677; GO:0005634; GO:0005654; GO:0005739; GO:0006357; GO:0006978; GO:0008285; GO:0010629; GO:0017053; GO:0042803; GO:0042826; GO:0043065; GO:0043392; GO:0043565; GO:0043922; GO:0043923; GO:0045736; GO:0045892; GO:0045893; GO:0065003; GO:0070888; GO:0071549; GO:1901990; GO:1990837; GO:2001269 26707 XM_044324810.1 249 303 197 384 247 Q8CHP8 4.38e-65 Glycerol-3-phosphate phosphatase (G3PP) (EC 3.1.3.21) (Aspartate-based ubiquitous Mg(2+)-dependent phosphatase) (AUM) (EC 3.1.3.48) (Phosphoglycolate phosphatase) (PGP) Mus musculus (Mouse) glycerol biosynthetic process [GO:0006114]; glycerophospholipid metabolic process [GO:0006650]; negative regulation of gluconeogenesis [GO:0045721] GO:0000121; GO:0000287; GO:0004725; GO:0005737; GO:0006114; GO:0006650; GO:0008967; GO:0016791; GO:0043136; GO:0043262; GO:0045721 26708 XM_044324810.1 249 303 197 384 247 Q8CHP8 4.38e-65 Glycerol-3-phosphate phosphatase (G3PP) (EC 3.1.3.21) (Aspartate-based ubiquitous Mg(2+)-dependent phosphatase) (AUM) (EC 3.1.3.48) (Phosphoglycolate phosphatase) (PGP) Mus musculus (Mouse) glycerol biosynthetic process [GO:0006114]; glycerophospholipid metabolic process [GO:0006650]; negative regulation of gluconeogenesis [GO:0045721] GO:0000121; GO:0000287; GO:0004725; GO:0005737; GO:0006114; GO:0006650; GO:0008967; GO:0016791; GO:0043136; GO:0043262; GO:0045721 26709 XM_029349296.2 38 59 0 47 0 NA NA NA NA NA NA 26710 XM_044324455.1 11 2 0 29 15 NA NA NA NA NA NA 26711 XM_029348469.2 18607 14985 7579 16241 11081 Q58DS9 8.32e-119 Ras-related protein Rab-5C (EC 3.6.5.2) Bos taurus (Bovine) endocytic recycling [GO:0032456]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] GO:0003925; GO:0005525; GO:0005886; GO:0010008; GO:0015031; GO:0016192; GO:0019003; GO:0031901; GO:0032456; GO:0042470 26712 XM_044321887.1 64 196 24 64 146 P0CM54 4.84e-26 Calcineurin subunit B (Calcineurin regulatory subunit) (Protein phosphatase 2B regulatory subunit) Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans) adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion [GO:0000754]; calcineurin-mediated signaling [GO:0097720]; cellular ion homeostasis [GO:0006873]; fungal-type cell wall organization [GO:0031505]; protein dephosphorylation [GO:0006470] GO:0000754; GO:0004723; GO:0005509; GO:0005955; GO:0006470; GO:0006873; GO:0008597; GO:0019902; GO:0031505; GO:0097720 26713 XM_044328710.1 19 21 16 31 18 Q5ZID2 1.23e-54 Programmed cell death protein 2-like Gallus gallus (Chicken) apoptotic process [GO:0006915] GO:0005737; GO:0006915 26714 XM_044315024.1 6 1 22 0 60 Q13443 7.09e-73 Disintegrin and metalloproteinase domain-containing protein 9 (ADAM 9) (EC 3.4.24.-) (Cellular disintegrin-related protein) (Meltrin-gamma) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) Homo sapiens (Human) amyloid precursor protein catabolic process [GO:0042987]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell migration [GO:0016477]; cell-cell adhesion mediated by integrin [GO:0033631]; cell-matrix adhesion [GO:0007160]; cellular response to lipopolysaccharide [GO:0071222]; integrin-mediated signaling pathway [GO:0007229]; keratinocyte differentiation [GO:0030216]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; monocyte activation [GO:0042117]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of macrophage fusion [GO:0034241]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of protein secretion [GO:0050714]; protein processing [GO:0016485]; response to calcium ion [GO:0051592]; response to glucocorticoid [GO:0051384]; response to hydrogen peroxide [GO:0042542]; response to manganese ion [GO:0010042]; response to tumor necrosis factor [GO:0034612]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0004222; GO:0005080; GO:0005178; GO:0005518; GO:0005615; GO:0005925; GO:0006509; GO:0007155; GO:0007160; GO:0007179; GO:0007229; GO:0008237; GO:0009897; GO:0009986; GO:0010042; GO:0016477; GO:0016485; GO:0017124; GO:0030216; GO:0030335; GO:0031293; GO:0033627; GO:0033630; GO:0033631; GO:0034241; GO:0034612; GO:0042117; GO:0042542; GO:0042987; GO:0043236; GO:0043406; GO:0046872; GO:0050714; GO:0051044; GO:0051384; GO:0051549; GO:0051592; GO:0070062; GO:0071222; GO:1902945 26715 XM_029346993.2 17 15 39 12 34 A1L1W9 4.13e-39 Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10) Danio rerio (Zebrafish) (Brachydanio rerio) aromatic amino acid transport [GO:0015801]; thyroid hormone transport [GO:0070327] GO:0005302; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0070327 26716 XR_003827438.2 400 500 456 503 302 NA NA NA NA NA NA 26717 XM_044328840.1 19 3 24 1 192 NA NA NA NA NA NA 26718 XR_006397421.1 0 0 0 1 25 NA NA NA NA NA NA 26719 XM_029332582.2 829 459 292 435 525 G5E8K5 1.13e-35 Ankyrin-3 (ANK-3) (Ankyrin-G) Mus musculus (Mouse) anterograde axonal transport [GO:0008089]; axon development [GO:0061564]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; clustering of voltage-gated sodium channels [GO:0045162]; establishment of protein localization [GO:0045184]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in cell [GO:0032507]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of endocytosis [GO:0045806]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of action potential [GO:0045760]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; regulation of protein targeting [GO:1903533]; signal transduction [GO:0007165]; synapse organization [GO:0050808] GO:0000281; GO:0005200; GO:0005737; GO:0005764; GO:0005886; GO:0005923; GO:0007009; GO:0007165; GO:0007409; GO:0007411; GO:0007528; GO:0008089; GO:0008092; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014069; GO:0014704; GO:0014731; GO:0016020; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030424; GO:0030425; GO:0030507; GO:0030674; GO:0030951; GO:0031594; GO:0032507; GO:0033268; GO:0033270; GO:0034112; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045162; GO:0045184; GO:0045202; GO:0045211; GO:0045296; GO:0045760; GO:0045806; GO:0045838; GO:0050808; GO:0061564; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:0140031; GO:1900827; GO:1901224; GO:1902260; GO:1903533; GO:1904115; GO:2000651; GO:2001259 26720 XM_029332582.2 829 459 292 435 525 G5E8K5 1.04e-28 Ankyrin-3 (ANK-3) (Ankyrin-G) Mus musculus (Mouse) anterograde axonal transport [GO:0008089]; axon development [GO:0061564]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; clustering of voltage-gated sodium channels [GO:0045162]; establishment of protein localization [GO:0045184]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in cell [GO:0032507]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of endocytosis [GO:0045806]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of action potential [GO:0045760]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; regulation of protein targeting [GO:1903533]; signal transduction [GO:0007165]; synapse organization [GO:0050808] GO:0000281; GO:0005200; GO:0005737; GO:0005764; GO:0005886; GO:0005923; GO:0007009; GO:0007165; GO:0007409; GO:0007411; GO:0007528; GO:0008089; GO:0008092; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014069; GO:0014704; GO:0014731; GO:0016020; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030424; GO:0030425; GO:0030507; GO:0030674; GO:0030951; GO:0031594; GO:0032507; GO:0033268; GO:0033270; GO:0034112; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045162; GO:0045184; GO:0045202; GO:0045211; GO:0045296; GO:0045760; GO:0045806; GO:0045838; GO:0050808; GO:0061564; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:0140031; GO:1900827; GO:1901224; GO:1902260; GO:1903533; GO:1904115; GO:2000651; GO:2001259 26721 XM_029332582.2 829 459 292 435 525 G5E8K5 1.54e-27 Ankyrin-3 (ANK-3) (Ankyrin-G) Mus musculus (Mouse) anterograde axonal transport [GO:0008089]; axon development [GO:0061564]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; clustering of voltage-gated sodium channels [GO:0045162]; establishment of protein localization [GO:0045184]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in cell [GO:0032507]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of endocytosis [GO:0045806]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of action potential [GO:0045760]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; regulation of protein targeting [GO:1903533]; signal transduction [GO:0007165]; synapse organization [GO:0050808] GO:0000281; GO:0005200; GO:0005737; GO:0005764; GO:0005886; GO:0005923; GO:0007009; GO:0007165; GO:0007409; GO:0007411; GO:0007528; GO:0008089; GO:0008092; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014069; GO:0014704; GO:0014731; GO:0016020; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030424; GO:0030425; GO:0030507; GO:0030674; GO:0030951; GO:0031594; GO:0032507; GO:0033268; GO:0033270; GO:0034112; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045162; GO:0045184; GO:0045202; GO:0045211; GO:0045296; GO:0045760; GO:0045806; GO:0045838; GO:0050808; GO:0061564; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:0140031; GO:1900827; GO:1901224; GO:1902260; GO:1903533; GO:1904115; GO:2000651; GO:2001259 26722 XM_029332582.2 829 459 292 435 525 G5E8K5 5.64e-27 Ankyrin-3 (ANK-3) (Ankyrin-G) Mus musculus (Mouse) anterograde axonal transport [GO:0008089]; axon development [GO:0061564]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; clustering of voltage-gated sodium channels [GO:0045162]; establishment of protein localization [GO:0045184]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in cell [GO:0032507]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of endocytosis [GO:0045806]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of action potential [GO:0045760]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; regulation of protein targeting [GO:1903533]; signal transduction [GO:0007165]; synapse organization [GO:0050808] GO:0000281; GO:0005200; GO:0005737; GO:0005764; GO:0005886; GO:0005923; GO:0007009; GO:0007165; GO:0007409; GO:0007411; GO:0007528; GO:0008089; GO:0008092; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014069; GO:0014704; GO:0014731; GO:0016020; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030424; GO:0030425; GO:0030507; GO:0030674; GO:0030951; GO:0031594; GO:0032507; GO:0033268; GO:0033270; GO:0034112; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045162; GO:0045184; GO:0045202; GO:0045211; GO:0045296; GO:0045760; GO:0045806; GO:0045838; GO:0050808; GO:0061564; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:0140031; GO:1900827; GO:1901224; GO:1902260; GO:1903533; GO:1904115; GO:2000651; GO:2001259 26723 XM_029332582.2 829 459 292 435 525 G5E8K5 7.41e-27 Ankyrin-3 (ANK-3) (Ankyrin-G) Mus musculus (Mouse) anterograde axonal transport [GO:0008089]; axon development [GO:0061564]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; clustering of voltage-gated sodium channels [GO:0045162]; establishment of protein localization [GO:0045184]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in cell [GO:0032507]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of endocytosis [GO:0045806]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of action potential [GO:0045760]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; regulation of protein targeting [GO:1903533]; signal transduction [GO:0007165]; synapse organization [GO:0050808] GO:0000281; GO:0005200; GO:0005737; GO:0005764; GO:0005886; GO:0005923; GO:0007009; GO:0007165; GO:0007409; GO:0007411; GO:0007528; GO:0008089; GO:0008092; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014069; GO:0014704; GO:0014731; GO:0016020; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030424; GO:0030425; GO:0030507; GO:0030674; GO:0030951; GO:0031594; GO:0032507; GO:0033268; GO:0033270; GO:0034112; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045162; GO:0045184; GO:0045202; GO:0045211; GO:0045296; GO:0045760; GO:0045806; GO:0045838; GO:0050808; GO:0061564; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:0140031; GO:1900827; GO:1901224; GO:1902260; GO:1903533; GO:1904115; GO:2000651; GO:2001259 26724 XM_029332582.2 829 459 292 435 525 G5E8K5 6.45e-26 Ankyrin-3 (ANK-3) (Ankyrin-G) Mus musculus (Mouse) anterograde axonal transport [GO:0008089]; axon development [GO:0061564]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; clustering of voltage-gated sodium channels [GO:0045162]; establishment of protein localization [GO:0045184]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in cell [GO:0032507]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of endocytosis [GO:0045806]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of action potential [GO:0045760]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; regulation of protein targeting [GO:1903533]; signal transduction [GO:0007165]; synapse organization [GO:0050808] GO:0000281; GO:0005200; GO:0005737; GO:0005764; GO:0005886; GO:0005923; GO:0007009; GO:0007165; GO:0007409; GO:0007411; GO:0007528; GO:0008089; GO:0008092; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014069; GO:0014704; GO:0014731; GO:0016020; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030424; GO:0030425; GO:0030507; GO:0030674; GO:0030951; GO:0031594; GO:0032507; GO:0033268; GO:0033270; GO:0034112; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045162; GO:0045184; GO:0045202; GO:0045211; GO:0045296; GO:0045760; GO:0045806; GO:0045838; GO:0050808; GO:0061564; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:0140031; GO:1900827; GO:1901224; GO:1902260; GO:1903533; GO:1904115; GO:2000651; GO:2001259 26725 XM_029332582.2 829 459 292 435 525 G5E8K5 1.17e-25 Ankyrin-3 (ANK-3) (Ankyrin-G) Mus musculus (Mouse) anterograde axonal transport [GO:0008089]; axon development [GO:0061564]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; clustering of voltage-gated sodium channels [GO:0045162]; establishment of protein localization [GO:0045184]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in cell [GO:0032507]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of endocytosis [GO:0045806]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of action potential [GO:0045760]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; regulation of protein targeting [GO:1903533]; signal transduction [GO:0007165]; synapse organization [GO:0050808] GO:0000281; GO:0005200; GO:0005737; GO:0005764; GO:0005886; GO:0005923; GO:0007009; GO:0007165; GO:0007409; GO:0007411; GO:0007528; GO:0008089; GO:0008092; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014069; GO:0014704; GO:0014731; GO:0016020; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030424; GO:0030425; GO:0030507; GO:0030674; GO:0030951; GO:0031594; GO:0032507; GO:0033268; GO:0033270; GO:0034112; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045162; GO:0045184; GO:0045202; GO:0045211; GO:0045296; GO:0045760; GO:0045806; GO:0045838; GO:0050808; GO:0061564; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:0140031; GO:1900827; GO:1901224; GO:1902260; GO:1903533; GO:1904115; GO:2000651; GO:2001259 26726 XM_029332582.2 829 459 292 435 525 G5E8K5 4.23e-24 Ankyrin-3 (ANK-3) (Ankyrin-G) Mus musculus (Mouse) anterograde axonal transport [GO:0008089]; axon development [GO:0061564]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; clustering of voltage-gated sodium channels [GO:0045162]; establishment of protein localization [GO:0045184]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in cell [GO:0032507]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of endocytosis [GO:0045806]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of action potential [GO:0045760]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; regulation of protein targeting [GO:1903533]; signal transduction [GO:0007165]; synapse organization [GO:0050808] GO:0000281; GO:0005200; GO:0005737; GO:0005764; GO:0005886; GO:0005923; GO:0007009; GO:0007165; GO:0007409; GO:0007411; GO:0007528; GO:0008089; GO:0008092; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014069; GO:0014704; GO:0014731; GO:0016020; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030424; GO:0030425; GO:0030507; GO:0030674; GO:0030951; GO:0031594; GO:0032507; GO:0033268; GO:0033270; GO:0034112; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045162; GO:0045184; GO:0045202; GO:0045211; GO:0045296; GO:0045760; GO:0045806; GO:0045838; GO:0050808; GO:0061564; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:0140031; GO:1900827; GO:1901224; GO:1902260; GO:1903533; GO:1904115; GO:2000651; GO:2001259 26727 XM_044320315.1 21 2 5 9 28 Q9TU53 3.82e-22 Cubilin Canis lupus familiaris (Dog) (Canis familiaris) cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031] GO:0005509; GO:0005765; GO:0005768; GO:0005905; GO:0008203; GO:0015031; GO:0016324; GO:0031419; GO:0031526; GO:0043235 26728 XM_029358488.2 885 856 595 864 687 Q9R0W9 2.99e-34 Neuronal acetylcholine receptor subunit alpha-6 Mus musculus (Mouse) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system process [GO:0050877]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of dopamine secretion [GO:0014059]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165] GO:0004888; GO:0005231; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0014059; GO:0016020; GO:0022848; GO:0030594; GO:0032991; GO:0034220; GO:0042391; GO:0042734; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051899; GO:0098691; GO:0099171; GO:1901363; GO:1904315 26729 XR_003827082.2 67 66 96 6 66 NA NA NA NA NA NA 26730 XR_006391837.1 42 67 285 28 79 NA NA NA NA NA NA 26731 XR_006392553.1 53 42 6 7 26 NA NA NA NA NA NA 26732 XR_006395050.1 5 0 12 2 0 NA NA NA NA NA NA 26733 XR_003825724.2 107 89 78 136 203 NA NA NA NA NA NA 26734 XM_029335185.2 17 22 17 28 15 NA NA NA NA NA NA 26735 XM_029341621.2 1817 1464 1412 2028 1908 Q86TM6 0 E3 ubiquitin-protein ligase synoviolin (EC 2.3.2.27) (RING-type E3 ubiquitin transferase synoviolin) (Synovial apoptosis inhibitor 1) Homo sapiens (Human) endoplasmic reticulum mannose trimming [GO:1904380]; ERAD pathway [GO:0036503]; immature B cell differentiation [GO:0002327]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; protein K48-linked ubiquitination [GO:0070936]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; retrograde protein transport, ER to cytosol [GO:0030970]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000836; GO:0000839; GO:0002327; GO:0005654; GO:0005737; GO:0005783; GO:0005789; GO:0005790; GO:0006511; GO:0016020; GO:0016567; GO:0030433; GO:0030970; GO:0036503; GO:0036513; GO:0044322; GO:0046872; GO:0050821; GO:0051082; GO:0051087; GO:0051117; GO:0061630; GO:0070936; GO:0140297; GO:1902236; GO:1904380; GO:1990381 26736 XM_044314860.1 0 0 0 16 64 NA NA NA NA NA NA 26737 XM_029332045.2 8222 3071 3277 8298 7851 NA NA NA NA NA NA 26738 XR_006393079.1 41 2 25 5 151 NA NA NA NA NA NA 26739 XM_044326624.1 11 0 0 2 0 NA NA NA NA NA NA 26740 XM_044313995.1 310 134 256 167 209 NA NA NA NA NA NA 26741 XM_029340203.2 10 9 0 0 0 NA NA NA NA NA NA 26742 XM_044325891.1 160 53 208 832 245 P48506 0 Glutamate--cysteine ligase catalytic subunit (EC 6.3.2.2) (GCS heavy chain) (Gamma-ECS) (Gamma-glutamylcysteine synthetase) Homo sapiens (Human) aging [GO:0007568]; blood vessel diameter maintenance [GO:0097746]; cell redox homeostasis [GO:0045454]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to glucose stimulus [GO:0071333]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to insulin stimulus [GO:0032869]; cellular response to mechanical stimulus [GO:0071260]; cellular response to thyroxine stimulus [GO:0097069]; cysteine metabolic process [GO:0006534]; glutamate metabolic process [GO:0006536]; glutathione biosynthetic process [GO:0006750]; L-ascorbic acid metabolic process [GO:0019852]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of hepatic stellate cell activation [GO:2000490]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; regulation of mitochondrial depolarization [GO:0051900]; response to activity [GO:0014823]; response to arsenic-containing substance [GO:0046685]; response to cadmium ion [GO:0046686]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to human chorionic gonadotropin [GO:0044752]; response to interleukin-1 [GO:0070555]; response to nitrosative stress [GO:0051409]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to xenobiotic stimulus [GO:0009410] GO:0000287; GO:0004357; GO:0005524; GO:0005739; GO:0005829; GO:0006534; GO:0006536; GO:0006750; GO:0006979; GO:0007568; GO:0007584; GO:0009408; GO:0009410; GO:0009725; GO:0014823; GO:0016595; GO:0017109; GO:0019852; GO:0031397; GO:0032436; GO:0032869; GO:0035729; GO:0043066; GO:0043524; GO:0043531; GO:0044344; GO:0044752; GO:0044877; GO:0045454; GO:0045892; GO:0046685; GO:0046686; GO:0051409; GO:0051900; GO:0070555; GO:0071260; GO:0071333; GO:0071372; GO:0097069; GO:0097746; GO:1901029; GO:2000490; GO:2001237 26743 XM_044307248.1 70 70 30 94 137 Q92820 5.38e-87 Gamma-glutamyl hydrolase (EC 3.4.19.9) (Conjugase) (GH) (Gamma-Glu-X carboxypeptidase) Homo sapiens (Human) tetrahydrofolylpolyglutamate metabolic process [GO:0046900] GO:0005576; GO:0005615; GO:0005634; GO:0005773; GO:0008238; GO:0008242; GO:0034722; GO:0035578; GO:0035580; GO:0042470; GO:0046900; GO:0070062; GO:1904724 26744 XR_006396309.1 79 12 47 13 62 P24045 2.26e-70 Gamma-aminobutyric acid receptor subunit beta-4 (GABA(A) receptor subunit beta-4) Gallus gallus (Chicken) chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165] GO:0004890; GO:0005231; GO:0005254; GO:0005886; GO:0007165; GO:0007268; GO:0030594; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:1902476; GO:1902711; GO:1904315 26745 XM_044322928.1 3369 3095 2122 3658 2678 NA NA NA NA NA NA 26746 XM_044317811.1 28 38 43 75 97 NA NA NA NA NA NA 26747 XM_044314994.1 12 0 30 1 45 NA NA NA NA NA NA 26748 XM_029354059.2 156 0 316 458 131 NA NA NA NA NA NA 26749 XM_029340732.2 301 210 185 228 201 NA NA NA NA NA NA 26750 XM_029327427.2 0 0 59 14 0 P63138 4.35e-69 Gamma-aminobutyric acid receptor subunit beta-2 (GABA(A) receptor subunit beta-2) Rattus norvegicus (Rat) cellular response to histamine [GO:0071420]; chemical synaptic transmission [GO:0007268]; chemical synaptic transmission, postsynaptic [GO:0099565]; chloride transmembrane transport [GO:1902476]; cochlea development [GO:0090102]; gamma-aminobutyric acid signaling pathway [GO:0007214]; inhibitory synapse assembly [GO:1904862]; inner ear receptor cell development [GO:0060119]; innervation [GO:0060384]; ion transmembrane transport [GO:0034220]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; nervous system process [GO:0050877]; neuron development [GO:0048666]; regulation of membrane potential [GO:0042391]; regulation of neuron apoptotic process [GO:0043523]; regulation of postsynaptic membrane potential [GO:0060078]; sensory perception of sound [GO:0007605]; signal transduction [GO:0007165]; synaptic transmission, GABAergic [GO:0051932] GO:0004890; GO:0005231; GO:0005237; GO:0005254; GO:0005829; GO:0005886; GO:0007165; GO:0007214; GO:0007268; GO:0007605; GO:0016020; GO:0022851; GO:0030594; GO:0030659; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0043523; GO:0043524; GO:0045202; GO:0048666; GO:0048787; GO:0050877; GO:0051932; GO:0060078; GO:0060119; GO:0060384; GO:0071420; GO:0090102; GO:0098978; GO:0098982; GO:0099507; GO:0099565; GO:0099634; GO:1901215; GO:1902476; GO:1902710; GO:1902711; GO:1904315; GO:1904862 26751 XM_029356461.2 1575 699 523 1074 586 Q9VQ37 1.13e-85 Mitochondrial carrier protein Rim2 Drosophila melanogaster (Fruit fly) cellular respiration [GO:0045333]; deoxynucleotide transport [GO:0030302]; locomotion [GO:0040011]; mitochondrial genome maintenance [GO:0000002]; mitochondrial transcription [GO:0006390]; mitochondrial transport [GO:0006839]; mitochondrion distribution [GO:0048311]; mitochondrion organization [GO:0007005]; pyrimidine nucleotide import into mitochondrion [GO:1990519] GO:0000002; GO:0005739; GO:0005743; GO:0006390; GO:0006839; GO:0007005; GO:0015218; GO:0030302; GO:0040011; GO:0045333; GO:0048311; GO:1990519 26752 XM_029358319.2 10 13 3 0 20 Q7PCJ9 6.88e-36 Thialysine N-epsilon-acetyltransferase (EC 2.3.1.-) (Diamine acetyltransferase 2) (EC 2.3.1.57) (Spermidine/spermine N(1)-acetyltransferase 2) (SSAT-2) Sus scrofa (Pig) spermidine acetylation [GO:0032918] GO:0004145; GO:0005737; GO:0008080; GO:0019809; GO:0032918 26753 XM_029334506.2 224 128 207 117 201 Q9PVM0 1.8e-29 Homeobox protein otx5-A (Orthodenticle homolog 5-A) (Xotx5) Xenopus laevis (African clawed frog) anterior/posterior pattern specification [GO:0009952]; eye photoreceptor cell fate commitment [GO:0042706]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000981; GO:0003677; GO:0005634; GO:0009952; GO:0042706; GO:0045944 26754 XM_044327918.1 1420 1129 819 1425 1519 P07756 0 Carbamoyl-phosphate synthase [ammonia], mitochondrial (EC 6.3.4.16) (Carbamoyl-phosphate synthetase I) (CPSase I) Rattus norvegicus (Rat) 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; anion homeostasis [GO:0055081]; carbamoyl phosphate biosynthetic process [GO:0070409]; cellular response to ammonium ion [GO:0071242]; cellular response to cAMP [GO:0071320]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to glucagon stimulus [GO:0071377]; cellular response to oleic acid [GO:0071400]; glutamine metabolic process [GO:0006541]; hepatocyte differentiation [GO:0070365]; homocysteine metabolic process [GO:0050667]; liver development [GO:0001889]; midgut development [GO:0007494]; nitric oxide metabolic process [GO:0046209]; nitrogen compound metabolic process [GO:0006807]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to cAMP [GO:0051591]; response to dexamethasone [GO:0071548]; response to food [GO:0032094]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to growth hormone [GO:0060416]; response to lipopolysaccharide [GO:0032496]; response to oleic acid [GO:0034201]; response to starvation [GO:0042594]; response to steroid hormone [GO:0048545]; response to toxic substance [GO:0009636]; response to xenobiotic stimulus [GO:0009410]; response to zinc ion [GO:0010043]; sequestering of metal ion [GO:0051238]; triglyceride catabolic process [GO:0019433]; urea cycle [GO:0000050]; vasodilation [GO:0042311] GO:0000050; GO:0001889; GO:0004087; GO:0004088; GO:0004175; GO:0005509; GO:0005524; GO:0005543; GO:0005730; GO:0005737; GO:0005739; GO:0005743; GO:0006207; GO:0006541; GO:0006807; GO:0007494; GO:0009410; GO:0009636; GO:0010043; GO:0014075; GO:0016595; GO:0019433; GO:0032094; GO:0032496; GO:0032991; GO:0033762; GO:0034201; GO:0036094; GO:0042311; GO:0042594; GO:0042645; GO:0043200; GO:0044344; GO:0044877; GO:0046209; GO:0046872; GO:0048545; GO:0050667; GO:0051238; GO:0051384; GO:0051591; GO:0055081; GO:0060416; GO:0070365; GO:0070409; GO:0071242; GO:0071320; GO:0071377; GO:0071400; GO:0071548; GO:0072341 26755 XM_029339229.2 49 65 46 22 30 Q5FYA8 7.7e-49 Arylsulfatase H (ASH) (EC 3.1.6.-) Homo sapiens (Human) NA GO:0004065; GO:0005788; GO:0016020; GO:0046872 26756 XM_029324509.2 3596 4169 2475 6144 5795 Q96AC1 0 Fermitin family homolog 2 (Kindlin-2) (Mitogen-inducible gene 2 protein) (MIG-2) (Pleckstrin homology domain-containing family C member 1) (PH domain-containing family C member 1) Homo sapiens (Human) adherens junction maintenance [GO:0034334]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; focal adhesion assembly [GO:0048041]; integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]; limb development [GO:0060173]; negative regulation of cell death [GO:0060548]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of vascular permeability [GO:0043116]; positive regulation of cell migration [GO:0030335]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of GTPase activity [GO:0043547]; positive regulation of integrin activation [GO:0033625]; positive regulation of mesenchymal stem cell proliferation [GO:1902462]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of wound healing, spreading of epidermal cells [GO:1903691]; protein localization to cell junction [GO:1902414]; protein localization to membrane [GO:0072657]; regulation of cell morphogenesis [GO:0022604]; regulation of cell shape [GO:0008360]; substrate adhesion-dependent cell spreading [GO:0034446]; transforming growth factor beta receptor signaling pathway [GO:0007179]; Wnt signaling pathway [GO:0016055] GO:0001725; GO:0003779; GO:0005178; GO:0005547; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0005912; GO:0005925; GO:0005938; GO:0007155; GO:0007160; GO:0007179; GO:0007229; GO:0008360; GO:0009986; GO:0010718; GO:0016055; GO:0019901; GO:0022604; GO:0030054; GO:0030055; GO:0030335; GO:0031234; GO:0031258; GO:0031674; GO:0033622; GO:0033625; GO:0034334; GO:0034446; GO:0034713; GO:0035505; GO:0043116; GO:0043547; GO:0045599; GO:0045669; GO:0046332; GO:0048041; GO:0051015; GO:0051496; GO:0051894; GO:0051897; GO:0060173; GO:0060548; GO:0070374; GO:0072657; GO:1900026; GO:1900182; GO:1902414; GO:1902462; GO:1903691 26757 XM_044318176.1 38 1061 41 166 54 Q6AZB8 2.26e-58 Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0004518; GO:0005634; GO:0005737; GO:0046872 26758 XM_029358355.2 286 29 40 419 133 Q3KP44 1.89e-63 Ankyrin repeat domain-containing protein 55 Homo sapiens (Human) NA NA 26759 XM_044322280.1 71 20 113 30 198 NA NA NA NA NA NA 26760 XM_029353285.2 33480 31869 17698 32050 20557 P69005 0 Actin, cytoskeletal 2B (EC 3.6.4.-) (Actin, cytoskeletal IIB) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005524; GO:0005737; GO:0005856; GO:0016787 26761 XM_044320501.1 3503 2596 2351 2106 2109 D3ZGB1 7.2e-33 Nuclear factor of activated T-cells 5 (NF-AT5) (T-cell transcription factor NFAT5) Rattus norvegicus (Rat) calcineurin-NFAT signaling cascade [GO:0033173]; cellular response to cytokine stimulus [GO:0071345]; cellular response to DNA damage stimulus [GO:0006974]; positive regulation of gene expression [GO:0010628]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R-loop processing [GO:0062176]; regulation of calcineurin-NFAT signaling cascade [GO:0070884]; regulation of transcription by RNA polymerase II [GO:0006357]; response to osmotic stress [GO:0006970] GO:0000978; GO:0000981; GO:0001228; GO:0003677; GO:0003682; GO:0005634; GO:0005654; GO:0005667; GO:0005694; GO:0005737; GO:0005829; GO:0006357; GO:0006970; GO:0006974; GO:0010628; GO:0033173; GO:0045944; GO:0062176; GO:0070884; GO:0071345; GO:1901224; GO:1904996; GO:1990837 26762 XM_044311460.1 158 124 141 187 339 NA NA NA NA NA NA 26763 XM_044313867.1 13 0 0 19 4 NA NA NA NA NA NA 26764 XR_006395416.1 5 0 0 0 10 NA NA NA NA NA NA 26765 XR_006395373.1 0 0 33 31 32 Q9VBW3 1.12e-62 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 26766 XR_006395373.1 0 0 33 31 32 Q9VBW3 1.12e-62 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 26767 XM_029335630.2 782 554 167 747 908 Q8K4R9 1.04e-28 Disks large-associated protein 5 (DAP-5) (Discs large homolog 7) (Disks large-associated protein DLG7) (Hepatoma up-regulated protein homolog) (HURP) Mus musculus (Mouse) centrosome localization [GO:0051642]; chromosome segregation [GO:0007059]; kinetochore assembly [GO:0051382]; mitotic spindle organization [GO:0007052]; regulation of mitotic cell cycle [GO:0007346]; signaling [GO:0023052] GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0007052; GO:0007059; GO:0007346; GO:0008017; GO:0023052; GO:0031616; GO:0034451; GO:0051382; GO:0051642 26768 XM_044326837.1 133 11 136 24 964 NA NA NA NA NA NA 26769 XM_029332514.2 2843 4272 3015 3850 4066 Q9W1V3 5.37e-149 rRNA 2'-O-methyltransferase fibrillarin (EC 2.1.1.-) (Histone-glutamine methyltransferase) Drosophila melanogaster (Fruit fly) box C/D RNA 3'-end processing [GO:0000494]; histone glutamine methylation [GO:1990258]; rRNA methylation [GO:0031167] GO:0000494; GO:0001651; GO:0003723; GO:0005730; GO:0008649; GO:0015030; GO:0031167; GO:0031428; GO:0032040; GO:1990258; GO:1990259 26770 XM_044328749.1 17 0 5 18 4 NA NA NA NA NA NA 26771 XM_029338843.2 0 0 166 0 213 B1WAR9 9.06e-65 Serine/threonine-protein kinase greatwall (GW) (GWL) (EC 2.7.11.1) (Microtubule-associated serine/threonine-protein kinase-like) (MAST-L) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic cell cycle [GO:0000278]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; protein phosphorylation [GO:0006468] GO:0000086; GO:0000278; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0006468; GO:0006974; GO:0032154; GO:0032515; GO:0051301; GO:0051721; GO:0106310 26772 XM_029338843.2 0 0 166 0 213 B1WAR9 1.02e-53 Serine/threonine-protein kinase greatwall (GW) (GWL) (EC 2.7.11.1) (Microtubule-associated serine/threonine-protein kinase-like) (MAST-L) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic cell cycle [GO:0000278]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; protein phosphorylation [GO:0006468] GO:0000086; GO:0000278; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0006468; GO:0006974; GO:0032154; GO:0032515; GO:0051301; GO:0051721; GO:0106310 26773 XM_029326553.2 4 0 17 1 4 NA NA NA NA NA NA 26774 XR_006395359.1 501 0 0 185 264 Q13523 3.51e-177 Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 kinase) (PRP4 pre-mRNA-processing factor 4 homolog) Homo sapiens (Human) mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; protein phosphorylation [GO:0006468]; RNA splicing [GO:0008380] GO:0000398; GO:0003723; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005694; GO:0006468; GO:0008380; GO:0016607; GO:0045292; GO:0071013; GO:0106310 26775 XM_029334101.2 294 165 144 256 237 Q4V7B1 3.1e-63 Protein CFAP20DC Rattus norvegicus (Rat) NA NA 26776 XR_006397367.1 39 50 29 61 90 NA NA NA NA NA NA 26777 XM_044321946.1 0 0 76 53 0 NA NA NA NA NA NA 26778 XM_029352405.2 178 158 163 207 321 Q2TBV6 1.27e-27 Coiled-coil domain-containing protein 124 Bos taurus (Bovine) cell cycle [GO:0007049]; cell division [GO:0051301]; transcription by RNA polymerase II [GO:0006366] GO:0003713; GO:0005634; GO:0005815; GO:0005829; GO:0005886; GO:0006366; GO:0007049; GO:0030496; GO:0051301 26779 XM_029350847.2 1209 909 914 1139 446 NA NA NA NA NA NA 26780 XR_006395237.1 70 37 20 90 181 NA NA NA NA NA NA 26781 XM_044312415.1 0 0 183 1 189 Q9NZM1 0 Myoferlin (Fer-1-like protein 3) Homo sapiens (Human) blood circulation [GO:0008015]; membrane fusion [GO:0061025]; muscle contraction [GO:0006936]; plasma membrane organization [GO:0007009]; plasma membrane repair [GO:0001778]; T-tubule organization [GO:0033292] GO:0001778; GO:0005543; GO:0005635; GO:0005886; GO:0005901; GO:0006936; GO:0007009; GO:0008015; GO:0030659; GO:0031410; GO:0031965; GO:0033292; GO:0043231; GO:0046872; GO:0061025; GO:0070062 26782 XM_044306751.1 20 0 3 0 3 NA NA NA NA NA NA 26783 XM_029331820.2 30 13 108 319 83 NA NA NA NA NA NA 26784 XM_029344881.2 237 567 312 0 538 Q8R5F3 1.07e-59 ADP-ribose glycohydrolase OARD1 (O-acetyl-ADP-ribose deacetylase 1) (EC 3.5.1.-) (Terminal ADP-ribose protein glycohydrolase 1) ([Protein ADP-ribosylglutamate] hydrolase OARD1) (EC 3.2.2.-) Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; peptidyl-glutamate ADP-deribosylation [GO:0140291]; protein de-ADP-ribosylation [GO:0051725]; purine nucleoside metabolic process [GO:0042278] GO:0001883; GO:0005654; GO:0005730; GO:0006974; GO:0042278; GO:0051725; GO:0061463; GO:0090734; GO:0140291; GO:0140293 26785 XM_029345831.2 3870 3323 4027 3327 3773 Q62277 8.52e-34 Synaptophysin (BM89 antigen) (Major synaptic vesicle protein p38) Mus musculus (Mouse) cellular response to organic substance [GO:0071310]; chemical synaptic transmission [GO:0007268]; endocytosis [GO:0006897]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of opioid receptor signaling pathway [GO:2000474]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic vesicle exocytosis [GO:2000300]; synaptic vesicle endocytosis [GO:0048488] GO:0000149; GO:0006897; GO:0007268; GO:0008021; GO:0014069; GO:0015485; GO:0016020; GO:0017075; GO:0019904; GO:0030672; GO:0031594; GO:0032991; GO:0042169; GO:0042734; GO:0042802; GO:0043005; GO:0043195; GO:0043229; GO:0044306; GO:0044309; GO:0044877; GO:0045202; GO:0048168; GO:0048169; GO:0048172; GO:0048471; GO:0048488; GO:0048786; GO:0060076; GO:0060203; GO:0071310; GO:0098685; GO:0098793; GO:2000300; GO:2000474 26786 XM_029346840.2 63 0 132 0 0 Q95YJ5 0 Thioredoxin domain-containing protein 3 homolog (Dynein intermediate chain 3) Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis) cell differentiation [GO:0030154]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside diphosphate phosphorylation [GO:0006165]; spermatogenesis [GO:0007283]; UTP biosynthetic process [GO:0006228] GO:0004550; GO:0006165; GO:0006183; GO:0006228; GO:0006241; GO:0007283; GO:0030154 26787 XR_006391777.1 37 10 3 20 21 NA NA NA NA NA NA 26788 XM_044319011.1 308 146 219 414 408 Q9H8H2 8.45e-170 Probable ATP-dependent RNA helicase DDX31 (EC 3.6.4.13) (DEAD box protein 31) (Helicain) Homo sapiens (Human) ribosome biogenesis [GO:0042254] GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005730; GO:0005794; GO:0016887; GO:0042254; GO:0043231 26789 XM_029329923.2 1436 1789 6 2779 951 O18334 1.47e-111 Ras-related protein Rab6 (Protein warthog) Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; compound eye morphogenesis [GO:0001745]; defense response to fungus [GO:0050832]; exocytosis [GO:0006887]; germarium-derived egg chamber formation [GO:0007293]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; oocyte microtubule cytoskeleton polarization [GO:0008103]; phototransduction [GO:0007602]; pole plasm oskar mRNA localization [GO:0045451]; protein targeting to Golgi apparatus [GO:0140450]; R7 cell development [GO:0045467]; Rab protein signal transduction [GO:0032482]; receptor recycling [GO:0001881]; regulation of postsynaptic membrane potential [GO:0060078]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0001745; GO:0001881; GO:0003779; GO:0003924; GO:0005525; GO:0005764; GO:0005776; GO:0005794; GO:0005829; GO:0006886; GO:0006887; GO:0006890; GO:0006891; GO:0007293; GO:0007411; GO:0007602; GO:0008103; GO:0012505; GO:0016192; GO:0031410; GO:0032482; GO:0042147; GO:0043025; GO:0043204; GO:0045202; GO:0045451; GO:0045467; GO:0050832; GO:0060078; GO:0140450 26790 XM_044319756.1 0 4 0 0 36 NA NA NA NA NA NA 26791 XM_029350871.2 36 0 0 8 126 NA NA NA NA NA NA 26792 XM_029345814.2 476 810 619 747 823 Q66J91 1.3e-72 S-adenosylmethionine sensor upstream of mTORC1 (Probable methyltransferase BMT2 homolog) (EC 2.1.1.-) Xenopus laevis (African clawed frog) cellular response to amino acid starvation [GO:0034198]; methylation [GO:0032259]; negative regulation of TORC1 signaling [GO:1904262] GO:0008168; GO:0032259; GO:0034198; GO:1904047; GO:1904262 26793 XM_044312489.1 0 2 1 0 13 NA NA NA NA NA NA 26794 XM_044314016.1 119 46 127 111 229 NA NA NA NA NA NA 26795 XM_044314897.1 0 0 43 0 0 Q9U6Y6 6.68e-110 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 26796 XM_029330066.2 24 1 4 22 63 NA NA NA NA NA NA 26797 XM_044316533.1 2387 2618 2680 2498 2843 Q05116 1.17e-56 Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase 1) (MAPKK 1) (EC 2.7.12.2) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Xenopus laevis (African clawed frog) NA GO:0004674; GO:0004708; GO:0004713; GO:0005524; GO:0005634; GO:0005737; GO:0005815; GO:0106310 26798 XM_044316533.1 2387 2618 2680 2498 2843 Q05116 1.17e-56 Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase 1) (MAPKK 1) (EC 2.7.12.2) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Xenopus laevis (African clawed frog) NA GO:0004674; GO:0004708; GO:0004713; GO:0005524; GO:0005634; GO:0005737; GO:0005815; GO:0106310 26799 XM_029358752.2 497 358 300 532 665 Q5R5L3 0 DnaJ homolog subfamily C member 10 (EC 1.8.4.-) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) protein folding in endoplasmic reticulum [GO:0034975]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0005788; GO:0015035; GO:0016671; GO:0030433; GO:0034975 26800 XM_044312883.1 59 59 158 90 84 NA NA NA NA NA NA 26801 XM_029351305.2 2671 2352 2142 3021 3596 Q9QYJ0 5.71e-166 DnaJ homolog subfamily A member 2 (mDj3) Mus musculus (Mouse) protein refolding [GO:0042026]; response to heat [GO:0009408] GO:0001671; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0009408; GO:0016020; GO:0030544; GO:0042026; GO:0046872; GO:0051082; GO:0051087 26802 XR_006396613.1 18 16 2 15 38 NA NA NA NA NA NA 26803 XR_006392992.1 41 2 25 5 151 NA NA NA NA NA NA 26804 XM_044311052.1 183 40 57 83 12 P16157 1.28e-51 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 26805 XM_044311052.1 183 40 57 83 12 P16157 8.17e-48 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 26806 XM_044311052.1 183 40 57 83 12 P16157 3.23e-45 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 26807 XM_044311052.1 183 40 57 83 12 P16157 6.99e-42 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 26808 XM_044311052.1 183 40 57 83 12 P16157 1.47e-28 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 26809 XM_029333630.2 645 200 176 813 1370 P54357 8.63e-28 Myosin-2 essential light chain (Myosin II essential light chain) (Non-muscle myosin essential light chain) Drosophila melanogaster (Fruit fly) actin filament-based movement [GO:0030048] GO:0005509; GO:0005829; GO:0016460; GO:0017022; GO:0030048; GO:0031475; GO:0031476; GO:0031477; GO:0032036 26810 XM_044310093.1 35 24 37 40 208 NA NA NA NA NA NA 26811 XR_003822772.2 360 93 18 20 266 NA NA NA NA NA NA 26812 XM_044315562.1 19 80 5 9 34 NA NA NA NA NA NA 26813 XM_029340004.2 1895 5869 5581 3409 2422 Q7T3H9 8.66e-70 Putative hydroxypyruvate isomerase (EC 5.3.1.22) Danio rerio (Zebrafish) (Brachydanio rerio) glyoxylate metabolic process [GO:0046487] GO:0008903; GO:0046487 26814 XM_044308679.1 58 0 3 8 9 D3YXG0 2.05e-66 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 26815 XM_044308679.1 58 0 3 8 9 D3YXG0 1.29e-51 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 26816 XM_044308679.1 58 0 3 8 9 D3YXG0 2.13e-47 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 26817 XM_044308679.1 58 0 3 8 9 D3YXG0 1.18e-40 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 26818 XM_044308679.1 58 0 3 8 9 D3YXG0 1.23e-40 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 26819 XM_044308679.1 58 0 3 8 9 D3YXG0 2.58e-40 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 26820 XM_044308679.1 58 0 3 8 9 D3YXG0 7.46e-39 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 26821 XM_044308679.1 58 0 3 8 9 D3YXG0 8.3e-37 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 26822 XM_044308679.1 58 0 3 8 9 D3YXG0 1.44e-36 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 26823 XM_044308679.1 58 0 3 8 9 D3YXG0 5.51e-35 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 26824 XM_044308679.1 58 0 3 8 9 D3YXG0 1.14e-26 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 26825 XM_029330725.2 679 728 471 375 212 P56377 5.24e-83 AP-1 complex subunit sigma-2 (Adaptor protein complex AP-1 subunit sigma-1B) (Adaptor-related protein complex 1 subunit sigma-1B) (Clathrin assembly protein complex 1 sigma-1B small chain) (Golgi adaptor HA1/AP1 adaptin sigma-1B subunit) (Sigma 1B subunit of AP-1 clathrin) (Sigma-adaptin 1B) (Sigma1B-adaptin) Homo sapiens (Human) intracellular protein transport [GO:0006886]; melanosome assembly [GO:1903232]; platelet dense granule organization [GO:0060155]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0005765; GO:0005769; GO:0005794; GO:0005829; GO:0005905; GO:0006886; GO:0016192; GO:0030119; GO:0030121; GO:0030659; GO:0032588; GO:0035615; GO:0043231; GO:0060155; GO:1903232 26826 XM_029336502.2 511 318 371 434 641 Q90744 8.19e-157 Alpha-N-acetylgalactosaminidase (EC 3.2.1.49) (Alpha-galactosidase B) Gallus gallus (Chicken) glycoside catabolic process [GO:0016139]; lipid metabolic process [GO:0006629]; oligosaccharide metabolic process [GO:0009311] GO:0004557; GO:0005737; GO:0005764; GO:0006629; GO:0008456; GO:0009311; GO:0016139 26827 XM_029335602.2 203 201 252 350 175 NA NA NA NA NA NA 26828 XM_044328573.1 2923 7428 1118 5219 2961 NA NA NA NA NA NA 26829 XM_044308622.1 0 0 0 56 0 NA NA NA NA NA NA 26830 XM_044320257.1 55 37 24 45 102 Q3SX07 6.99e-45 tRNA pseudouridine(38/39) synthase (EC 5.4.99.45) (tRNA pseudouridine synthase 3) (tRNA pseudouridylate synthase 3) (tRNA-uridine isomerase 3) Bos taurus (Bovine) mRNA pseudouridine synthesis [GO:1990481]; tRNA pseudouridine synthesis [GO:0031119] GO:0003723; GO:0005634; GO:0005737; GO:0009982; GO:0031119; GO:0106029; GO:1990481 26831 XM_044320257.1 55 37 24 45 102 Q3SX07 6.99e-45 tRNA pseudouridine(38/39) synthase (EC 5.4.99.45) (tRNA pseudouridine synthase 3) (tRNA pseudouridylate synthase 3) (tRNA-uridine isomerase 3) Bos taurus (Bovine) mRNA pseudouridine synthesis [GO:1990481]; tRNA pseudouridine synthesis [GO:0031119] GO:0003723; GO:0005634; GO:0005737; GO:0009982; GO:0031119; GO:0106029; GO:1990481 26832 XM_044317352.1 953 0 0 0 0 NA NA NA NA NA NA 26833 XM_044325469.1 6 187 0 417 6 NA NA NA NA NA NA 26834 XM_029331384.2 4 131 0 154 32 D3YXG0 3.87e-72 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 26835 XM_029331384.2 4 131 0 154 32 D3YXG0 6.07e-63 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 26836 XR_006391774.1 8 0 4 0 14 NA NA NA NA NA NA 26837 XM_044318463.1 1582 1435 36 120 641 P55024 1.39e-117 Tyrosinase (EC 1.14.18.1) (Monophenol monooxygenase) Gallus gallus (Chicken) melanin biosynthetic process [GO:0042438]; response to blue light [GO:0009637] GO:0004503; GO:0009637; GO:0033162; GO:0042438; GO:0042470; GO:0046872 26838 XR_006397656.1 0 0 0 10 0 NA NA NA NA NA NA 26839 XM_029350609.2 2 6 0 15 17 NA NA NA NA NA NA 26840 XM_029348992.2 0 40 30 0 0 P25931 1.04e-23 RYamide receptor (Neuropeptide Y-like receptor) (NPY-R) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218] GO:0001653; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0016020 26841 XR_006394976.1 264 206 263 709 747 Q9HAR2 4e-55 Adhesion G protein-coupled receptor L3 (Calcium-independent alpha-latrotoxin receptor 3) (CIRL-3) (Latrophilin-3) (Lectomedin-3) Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; brain development [GO:0007420]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; G protein-coupled receptor signaling pathway [GO:0007186]; neuron migration [GO:0001764]; synapse assembly [GO:0007416] GO:0001764; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007166; GO:0007186; GO:0007189; GO:0007416; GO:0007420; GO:0016020; GO:0030246; GO:0030424; GO:0098742; GO:0098978 26842 XM_029348757.2 13 11 2 5 12 Q5XGY9 3.22e-67 Meiotic nuclear division protein 1 homolog Xenopus laevis (African clawed frog) reciprocal meiotic recombination [GO:0007131] GO:0003690; GO:0005634; GO:0007131 26843 XM_029340646.2 3828 2675 1410 1995 1102 Q6NWZ9 1.01e-78 Cysteine dioxygenase type 1 (EC 1.13.11.20) (Cysteine dioxygenase type I) (CDO) (CDO-I) Danio rerio (Zebrafish) (Brachydanio rerio) L-cysteine catabolic process [GO:0019448]; taurine biosynthetic process [GO:0042412] GO:0008198; GO:0008270; GO:0016151; GO:0016702; GO:0017172; GO:0019448; GO:0042412 26844 XR_006395549.1 22 87 101 130 79 NA NA NA NA NA NA 26845 XM_029353185.2 0 0 0 0 15 NA NA NA NA NA NA 26846 XM_044310763.1 1815 1420 1705 2312 2798 NA NA NA NA NA NA 26847 XM_044311643.1 98 46 59 54 149 NA NA NA NA NA NA 26848 XM_044307284.1 85 0 16 9 0 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 26849 XM_044307284.1 85 0 16 9 0 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 26850 XM_044307284.1 85 0 16 9 0 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 26851 XM_044307284.1 85 0 16 9 0 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 26852 XM_044307284.1 85 0 16 9 0 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 26853 XM_044307284.1 85 0 16 9 0 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 26854 XM_044307284.1 85 0 16 9 0 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 26855 XM_044307284.1 85 0 16 9 0 P07207 2.88e-172 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 26856 XM_044307284.1 85 0 16 9 0 P07207 1.37e-135 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 26857 XM_029349321.2 1710 1414 833 923 1013 Q8R0S2 2.32e-83 IQ motif and SEC7 domain-containing protein 1 Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; dendritic spine development [GO:0060996]; positive regulation of focal adhesion disassembly [GO:0120183]; positive regulation of keratinocyte migration [GO:0051549]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; regulation of ARF protein signal transduction [GO:0032012]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149] GO:0005085; GO:0005730; GO:0008021; GO:0008289; GO:0019901; GO:0030036; GO:0032012; GO:0043231; GO:0051549; GO:0060996; GO:0098685; GO:0098978; GO:0099092; GO:0099149; GO:0099170; GO:0120183 26858 XM_029353080.2 22 0 4 8 27 NA NA NA NA NA NA 26859 XM_044326022.1 0 30 0 0 0 Q8CJG0 3.7e-153 Protein argonaute-2 (Argonaute2) (mAgo2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (Piwi/argonaute family protein meIF2C2) (Protein slicer) Mus musculus (Mouse) cell differentiation [GO:0030154]; miRNA metabolic process [GO:0010586]; miRNA processing [GO:0035196]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; miRNA-mediated gene silencing by mRNA destabilization [GO:0035279]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; negative regulation of translational initiation [GO:0045947]; positive regulation of angiogenesis [GO:0045766]; positive regulation of gene expression [GO:0010628]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of trophoblast cell migration [GO:1901165]; post-embryonic development [GO:0009791]; pre-miRNA processing [GO:0031054]; RISC complex assembly [GO:0070922]; RNA secondary structure unwinding [GO:0010501]; RNA-mediated gene silencing [GO:0031047]; siRNA processing [GO:0030422]; siRNA-mediated gene silencing by mRNA destabilization [GO:0090625] GO:0000340; GO:0000932; GO:0000993; GO:0001046; GO:0003723; GO:0003725; GO:0003727; GO:0003729; GO:0004521; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0005844; GO:0005845; GO:0008022; GO:0009791; GO:0010501; GO:0010586; GO:0010628; GO:0016442; GO:0030154; GO:0030422; GO:0030425; GO:0031047; GO:0031054; GO:0035196; GO:0035197; GO:0035198; GO:0035278; GO:0035279; GO:0036464; GO:0042985; GO:0045766; GO:0045944; GO:0045947; GO:0046872; GO:0060213; GO:0070062; GO:0070551; GO:0070578; GO:0070922; GO:0090624; GO:0090625; GO:0098808; GO:1900153; GO:1901165; GO:1990904 26860 XR_006395696.1 2 4 44 12 109 NA NA NA NA NA NA 26861 XM_044328514.1 410 190 204 277 333 Q61818 3.91e-21 Retinoic acid-induced protein 1 Mus musculus (Mouse) circadian regulation of gene expression [GO:0032922]; negative regulation of multicellular organism growth [GO:0040015]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal system development [GO:0001501] GO:0001501; GO:0005634; GO:0005654; GO:0005737; GO:0006357; GO:0032922; GO:0040015; GO:0045893; GO:0046872 26862 XM_029332051.2 777 293 171 167 715 NA NA NA NA NA NA 26863 XM_029345042.2 323 0 0 0 231 NA NA NA NA NA NA 26864 XR_006391490.1 462 437 290 873 835 Q5PRF9 1.87e-73 Protein Smaug homolog 2 (Smaug 2) (hSmaug2) (Sterile alpha motif domain-containing protein 4B) (SAM domain-containing protein 4B) Homo sapiens (Human) nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289] GO:0000289; GO:0000932; GO:0003723; GO:0003729; GO:0005634; GO:0005829; GO:0030371 26865 XR_006392384.1 0 73 157 0 0 P13595 3.18e-39 Neural cell adhesion molecule 1 (N-CAM-1) (NCAM-1) (CD antigen CD56) Mus musculus (Mouse) aging [GO:0007568]; axonal fasciculation [GO:0007413]; calcium-mediated signaling [GO:0019722]; cell surface receptor signaling pathway [GO:0007166]; commissural neuron axon guidance [GO:0071679]; homotypic cell-cell adhesion [GO:0034109]; learning or memory [GO:0007611]; modulation of chemical synaptic transmission [GO:0050804]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell death [GO:0060548]; neuron development [GO:0048666]; neuron projection development [GO:0031175]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; regulation of exocyst assembly [GO:0001928]; regulation of semaphorin-plexin signaling pathway [GO:2001260]; regulation of sensory perception of pain [GO:0051930]; response to cocaine [GO:0042220]; response to lead ion [GO:0010288]; response to xenobiotic stimulus [GO:0009410]; thalamus development [GO:0021794] GO:0001928; GO:0005829; GO:0005886; GO:0005911; GO:0007166; GO:0007413; GO:0007568; GO:0007611; GO:0008201; GO:0009410; GO:0009897; GO:0009986; GO:0010288; GO:0019722; GO:0019902; GO:0021794; GO:0030275; GO:0030424; GO:0030426; GO:0031175; GO:0033555; GO:0034109; GO:0042220; GO:0042734; GO:0043005; GO:0043025; GO:0043209; GO:0045211; GO:0048666; GO:0050804; GO:0050850; GO:0051930; GO:0060045; GO:0060548; GO:0071679; GO:0098685; GO:0098978; GO:2001260 26866 XM_044324417.1 11 144 60 52 793 NA NA NA NA NA NA 26867 XM_044314046.1 0 0 0 0 33 NA NA NA NA NA NA 26868 XR_003824911.2 13 6 1 5 6 NA NA NA NA NA NA 26869 XR_006396181.1 213 73 67 115 130 NA NA NA NA NA NA 26870 XM_029331268.2 4429 3647 2422 3544 2980 Q3T100 1.76e-36 Microsomal glutathione S-transferase 3 (Microsomal GST-3) (Glutathione peroxidase MGST3) (EC 1.11.1.-) (Microsomal glutathione S-transferase III) (Microsomal GST-III) Bos taurus (Bovine) lipid metabolic process [GO:0006629] GO:0004364; GO:0004602; GO:0005635; GO:0005783; GO:0005789; GO:0006629 26871 XM_029332270.2 3616 3749 1123 2148 1762 Q99MN1 0 Lysine--tRNA ligase (EC 2.7.7.-) (EC 6.1.1.6) (Lysyl-tRNA synthetase) (LysRS) Mus musculus (Mouse) basophil activation involved in immune response [GO:0002276]; diadenosine tetraphosphate biosynthetic process [GO:0015966]; ERK1 and ERK2 cascade [GO:0070371]; lysyl-tRNA aminoacylation [GO:0006430]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of inflammatory response to antigenic stimulus [GO:0002863]; positive regulation of macrophage activation [GO:0043032]; response to X-ray [GO:0010165] GO:0000049; GO:0002276; GO:0002863; GO:0003877; GO:0004824; GO:0005524; GO:0005615; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0005886; GO:0006430; GO:0010165; GO:0015966; GO:0016597; GO:0017101; GO:0042802; GO:0042803; GO:0043032; GO:0045893; GO:0070371; GO:0097110 26872 XR_006394660.1 3251 3240 1910 1887 1544 NA NA NA NA NA NA 26873 XM_029346845.2 190 54 105 122 225 Q505F5 5.47e-93 Leucine-rich repeat-containing protein 47 Mus musculus (Mouse) phenylalanyl-tRNA aminoacylation [GO:0006432] GO:0003723; GO:0004826; GO:0006432 26874 XM_044318042.1 179 104 57 95 120 A3KN83 4.37e-35 Protein strawberry notch homolog 1 (Monocyte protein 3) (MOP-3) Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355]; regulation of response to stimulus [GO:0048583] GO:0005634; GO:0006355; GO:0031490; GO:0042393; GO:0048583 26875 XM_029358652.2 6 0 0 0 0 Q71B07 0 Probable C-mannosyltransferase DPY19L3 (EC 2.4.1.-) (Dpy-19-like protein 3) (Protein dpy-19 homolog 3) Mus musculus (Mouse) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan [GO:0018406] GO:0000030; GO:0005637; GO:0018406 26876 XM_044325192.1 9 27 4 0 113 P09917 4.34e-77 Polyunsaturated fatty acid 5-lipoxygenase (EC 1.13.11.-) (Arachidonate 5-lipoxygenase) (5-LO) (5-lipoxygenase) (EC 1.13.11.34) Homo sapiens (Human) arachidonic acid metabolic process [GO:0019369]; dendritic cell migration [GO:0036336]; glucose homeostasis [GO:0042593]; hepoxilin biosynthetic process [GO:0051122]; humoral immune response [GO:0006959]; leukocyte chemotaxis involved in inflammatory response [GO:0002232]; leukocyte migration involved in inflammatory response [GO:0002523]; leukotriene A4 biosynthetic process [GO:1901753]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; leukotriene production involved in inflammatory response [GO:0002540]; linoleic acid metabolic process [GO:0043651]; lipid oxidation [GO:0034440]; lipoxin biosynthetic process [GO:2001301]; lipoxygenase pathway [GO:0019372]; long-chain fatty acid biosynthetic process [GO:0042759]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of inflammatory response [GO:0050728]; negative regulation of response to endoplasmic reticulum stress [GO:1903573]; negative regulation of sprouting angiogenesis [GO:1903671]; negative regulation of vascular wound healing [GO:0061044]; negative regulation of wound healing [GO:0061045]; positive regulation of bone mineralization [GO:0030501]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; regulation of cellular response to oxidative stress [GO:1900407]; regulation of cytokine production involved in inflammatory response [GO:1900015]; regulation of fat cell differentiation [GO:0045598]; regulation of inflammatory response [GO:0050727]; regulation of inflammatory response to wounding [GO:0106014]; regulation of insulin secretion [GO:0050796]; regulation of reactive oxygen species biosynthetic process [GO:1903426] GO:0001937; GO:0002232; GO:0002523; GO:0002540; GO:0004051; GO:0004052; GO:0005506; GO:0005576; GO:0005615; GO:0005635; GO:0005641; GO:0005654; GO:0005829; GO:0006691; GO:0006959; GO:0016363; GO:0016525; GO:0016702; GO:0016787; GO:0019369; GO:0019370; GO:0019372; GO:0030501; GO:0031965; GO:0034440; GO:0034774; GO:0036336; GO:0036403; GO:0042593; GO:0042759; GO:0043651; GO:0045598; GO:0048471; GO:0050727; GO:0050728; GO:0050796; GO:0051122; GO:0061044; GO:0061045; GO:0106014; GO:1900015; GO:1900407; GO:1901753; GO:1903426; GO:1903573; GO:1903671; GO:1904813; GO:1904999; GO:2001301 26877 XM_029356773.2 0 0 0 30 17 Q96P65 2.16e-25 Pyroglutamylated RF-amide peptide receptor (AQ27) (G-protein coupled receptor 103) (Orexigenic neuropeptide QRFP receptor) (SP9155) Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:0016020 26878 XR_006397223.1 9 0 33 66 65 NA NA NA NA NA NA 26879 XM_044308733.1 8 0 7 1 0 NA NA NA NA NA NA 26880 XM_044329348.1 0 14 41 0 0 Q96AY4 2.91e-98 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26881 XM_044329348.1 0 14 41 0 0 Q96AY4 4.12e-68 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26882 XM_044323167.1 1067 385 900 675 536 NA NA NA NA NA NA 26883 XM_029328944.2 273 160 142 135 295 Q86X83 4.31e-67 COMM domain-containing protein 2 Homo sapiens (Human) NA GO:0005737 26884 XR_006397184.1 51 94 58 54 73 Q6P7Q4 1.05e-65 Lactoylglutathione lyase (EC 4.4.1.5) (Aldoketomutase) (Glyoxalase I) (Glx I) (Ketone-aldehyde mutase) (Methylglyoxalase) (S-D-lactoylglutathione methylglyoxal lyase) Rattus norvegicus (Rat) carbohydrate metabolic process [GO:0005975]; glutathione metabolic process [GO:0006749]; methylglyoxal metabolic process [GO:0009438]; negative regulation of apoptotic process [GO:0043066]; osteoclast differentiation [GO:0030316]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0004462; GO:0005654; GO:0005829; GO:0005886; GO:0005975; GO:0006357; GO:0006749; GO:0008270; GO:0009438; GO:0030316; GO:0043066 26885 XM_029324576.2 800 96 288 1024 416 Q92545 0 Transmembrane protein 131 (Protein RW1) Homo sapiens (Human) NA GO:0016020 26886 XM_044323842.1 0 0 0 0 35 P08419 3.26e-47 Chymotrypsin-like elastase family member 2A (EC 3.4.21.71) (Elastase-2) (Elastase-2A) Sus scrofa (Pig) insulin catabolic process [GO:1901143]; proteolysis [GO:0006508]; regulation of insulin secretion [GO:0050796]; regulation of platelet aggregation [GO:0090330]; response to insulin [GO:0032868] GO:0004175; GO:0004252; GO:0005576; GO:0005615; GO:0006508; GO:0032868; GO:0050796; GO:0090330; GO:1901143 26887 XM_029340894.2 652 351 285 402 637 Q9NVP1 0 ATP-dependent RNA helicase DDX18 (EC 3.6.4.13) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb) Homo sapiens (Human) maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463] GO:0000463; GO:0003723; GO:0003724; GO:0005524; GO:0005694; GO:0005730; GO:0016020; GO:0016887 26888 XM_044326332.1 0 0 0 0 29 Q91175 1.19e-42 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (MAR1) Oryzias latipes (Japanese rice fish) (Japanese killifish) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of vasoconstriction [GO:0045907] GO:0001996; GO:0004930; GO:0004937; GO:0005886; GO:0007200; GO:0007204; GO:0007267; GO:0043410; GO:0045907; GO:0071880 26889 XM_029332719.2 0 0 0 55 291 NA NA NA NA NA NA 26890 XM_044318586.1 0 0 0 5 41 Q68F72 7.82e-82 Solute carrier family 15 member 4 Xenopus laevis (African clawed frog) dipeptide import across plasma membrane [GO:0140206]; innate immune response [GO:0045087]; mast cell homeostasis [GO:0033023]; peptidoglycan transport [GO:0015835]; positive regulation of innate immune response [GO:0045089]; positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [GO:0070430]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of toll-like receptor 7 signaling pathway [GO:0034157]; positive regulation of toll-like receptor 8 signaling pathway [GO:0034161]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; protein transport [GO:0015031]; regulation of isotype switching to IgG isotypes [GO:0048302]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424] GO:0005290; GO:0005765; GO:0015031; GO:0015333; GO:0015647; GO:0015835; GO:0031901; GO:0033023; GO:0034157; GO:0034161; GO:0034165; GO:0036020; GO:0045087; GO:0045089; GO:0048302; GO:0070424; GO:0070430; GO:0070434; GO:0071916; GO:0140206 26891 XM_044327991.1 2 0 9 0 2 NA NA NA NA NA NA 26892 XM_044321713.1 462 265 276 297 399 Q5E9U6 3.49e-95 Protein Wnt-16 Bos taurus (Bovine) Wnt signaling pathway [GO:0016055] GO:0005102; GO:0005576; GO:0016055 26893 XM_044308766.1 6108 6610 2976 4812 5922 Q0KIA2 1.52e-54 PP2C-like domain-containing protein CG9801 Drosophila melanogaster (Fruit fly) NA NA 26894 XM_044326946.1 0 0 0 6 0 NA NA NA NA NA NA 26895 XM_029357992.2 2077 2363 1142 1451 1710 P56101 1.66e-45 DnaJ homolog subfamily C member 5 (CCCS1) (Cysteine string protein) (CSP) Tetronarce californica (Pacific electric ray) (Torpedo californica) NA GO:0005829; GO:0005886; GO:0016020; GO:0042470; GO:0042584 26896 XM_029357919.2 877 491 364 963 681 Q91VN6 0 Probable ATP-dependent RNA helicase DDX41 (EC 3.6.4.13) (DEAD box protein 41) Mus musculus (Mouse) cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to interferon-beta [GO:0035458]; defense response to virus [GO:0051607]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000398; GO:0003677; GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005681; GO:0005783; GO:0008283; GO:0016887; GO:0030154; GO:0035458; GO:0045944; GO:0046872; GO:0051607; GO:0071013 26897 XM_029336628.2 0 0 0 0 150 Q9Y2B0 1.05e-36 Protein canopy homolog 2 (MIR-interacting saposin-like protein) (Putative secreted protein Zsig9) (Transmembrane protein 4) Homo sapiens (Human) negative regulation of gene expression [GO:0010629]; positive regulation of low-density lipoprotein receptor activity [GO:1905599]; regulation of low-density lipoprotein particle clearance [GO:0010988] GO:0005783; GO:0010629; GO:0010988; GO:1905599 26898 XM_044321711.1 0 0 0 0 99 A4D0V7 4.25e-99 Cadherin-like and PC-esterase domain-containing protein 1 Homo sapiens (Human) NA GO:0005783 26899 XR_006396670.1 0 0 3 20 0 NA NA NA NA NA NA 26900 XR_006393476.1 24 16 2 13 9 NA NA NA NA NA NA 26901 XM_029338165.2 813 491 332 534 773 NA NA NA NA NA NA 26902 XM_044318147.1 144 69 142 193 147 Q09470 6.09e-122 Potassium voltage-gated channel subfamily A member 1 (Voltage-gated K(+) channel HuKI) (Voltage-gated potassium channel HBK1) (Voltage-gated potassium channel subunit Kv1.1) Homo sapiens (Human) axon development [GO:0061564]; cell communication by electrical coupling [GO:0010644]; cellular response to magnesium ion [GO:0071286]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; corpus callosum development [GO:0022038]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; detection of mechanical stimulus involved in sensory perception of touch [GO:0050976]; hippocampus development [GO:0021766]; magnesium ion homeostasis [GO:0010960]; neuroblast proliferation [GO:0007405]; neuromuscular process [GO:0050905]; neuronal action potential [GO:0019228]; neuronal signal transduction [GO:0023041]; optic nerve development [GO:0021554]; positive regulation of voltage-gated potassium channel activity [GO:1903818]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; protein localization [GO:0008104]; regulation of membrane potential [GO:0042391]; regulation of muscle contraction [GO:0006937]; startle response [GO:0001964] GO:0001964; GO:0005249; GO:0005251; GO:0005267; GO:0005783; GO:0005829; GO:0005886; GO:0006813; GO:0006937; GO:0007268; GO:0007405; GO:0008076; GO:0008104; GO:0009986; GO:0010644; GO:0010960; GO:0015079; GO:0016020; GO:0016324; GO:0019228; GO:0021554; GO:0021766; GO:0021987; GO:0022038; GO:0023041; GO:0030054; GO:0030425; GO:0031410; GO:0033270; GO:0042391; GO:0042734; GO:0043025; GO:0043194; GO:0043204; GO:0043679; GO:0044224; GO:0044305; GO:0045202; GO:0045211; GO:0050905; GO:0050966; GO:0050976; GO:0051260; GO:0061564; GO:0070161; GO:0071286; GO:0071805; GO:0097718; GO:0098978; GO:0099508; GO:1903818; GO:1905030 26903 XR_006393119.1 2 405 154 308 486 NA NA NA NA NA NA 26904 XR_006395779.1 53 44 35 65 24 NA NA NA NA NA NA 26905 XM_044319336.1 1517 1225 706 1660 1225 A7E379 1.03e-112 Protein tyrosine phosphatase domain-containing protein 1 (EC 3.1.3.-) Bos taurus (Bovine) cell projection organization [GO:0030030]; protein dephosphorylation [GO:0006470] GO:0006470; GO:0008138; GO:0030030 26906 XR_006394182.1 6 0 0 0 0 NA NA NA NA NA NA 26907 XR_003826740.2 113 371 167 70 233 NA NA NA NA NA NA 26908 XM_029356517.2 105 0 7 52 0 NA NA NA NA NA NA 26909 XR_003823092.2 2 92 2 26 133 NA NA NA NA NA NA 26910 XM_044320457.1 682 214 503 794 600 A4D1B5 1.51e-21 Gamma-secretase-activating protein (GSAP) (Protein pigeon homolog) [Cleaved into: Gamma-secretase-activating protein 16 kDa C-terminal form (GSAP-16K)] Homo sapiens (Human) positive regulation of amyloid-beta formation [GO:1902004]; regulation of proteolysis [GO:0030162] GO:0001540; GO:0005802; GO:0030162; GO:1902004 26911 XM_029344409.2 721 726 399 783 518 Q9JLI7 0 Sperm-associated antigen 6 (Axoneme central apparatus protein) (Protein PF16 homolog) Mus musculus (Mouse) cell division [GO:0051301]; cerebrospinal fluid circulation [GO:0090660]; cilium movement [GO:0003341]; ear development [GO:0043583]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of localization in cell [GO:0051649]; fibroblast migration [GO:0010761]; filopodium assembly [GO:0046847]; flagellated sperm motility [GO:0030317]; motile cilium assembly [GO:0044458]; mucociliary clearance [GO:0120197]; neuron projection extension [GO:1990138]; non-motile cilium assembly [GO:1905515]; protein localization [GO:0008104]; regulation of cilium beat frequency [GO:0003356]; regulation of establishment of planar polarity [GO:0090175]; sperm axoneme assembly [GO:0007288]; spermatogenesis [GO:0007283]; stress fiber assembly [GO:0043149]; substrate-dependent cell migration, cell attachment to substrate [GO:0006931]; ventricular system development [GO:0021591] GO:0001669; GO:0002177; GO:0003341; GO:0003351; GO:0003356; GO:0005576; GO:0005829; GO:0005874; GO:0005930; GO:0006931; GO:0007283; GO:0007288; GO:0008017; GO:0008104; GO:0010761; GO:0015630; GO:0021591; GO:0030317; GO:0031410; GO:0043149; GO:0043583; GO:0044458; GO:0045198; GO:0046847; GO:0051301; GO:0051649; GO:0090175; GO:0090660; GO:0097228; GO:0120197; GO:0120249; GO:1905515; GO:1990138; GO:1990716 26912 XM_029351064.2 2352 2151 1529 1857 1882 Q8BTI9 0 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (PI3-kinase subunit beta) (PI3K-beta) (PI3Kbeta) (PtdIns-3-kinase subunit beta) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta) (PtdIns-3-kinase subunit p110-beta) (p110beta) (Serine/threonine protein kinase PIK3CB) (EC 2.7.11.1) Mus musculus (Mouse) angiogenesis involved in wound healing [GO:0060055]; autophagy [GO:0006914]; cell migration [GO:0016477]; cellular calcium ion homeostasis [GO:0006874]; embryonic cleavage [GO:0040016]; endocytosis [GO:0006897]; endothelial cell proliferation [GO:0001935]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of sprouting angiogenesis [GO:1903671]; negative regulation of vascular endothelial growth factor signaling pathway [GO:1900747]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol phosphate biosynthetic process [GO:0046854]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; phosphatidylinositol-mediated signaling [GO:0048015]; phosphorylation [GO:0016310]; platelet activation [GO:0030168]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of gene expression [GO:0010628]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Rac protein signal transduction [GO:0035022]; regulation of cell-matrix adhesion [GO:0001952]; response to ischemia [GO:0002931]; sphingosine-1-phosphate receptor signaling pathway [GO:0003376] GO:0001935; GO:0001952; GO:0002931; GO:0003376; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0005886; GO:0005942; GO:0005943; GO:0006874; GO:0006897; GO:0006914; GO:0007156; GO:0010595; GO:0010628; GO:0014065; GO:0016020; GO:0016301; GO:0016303; GO:0016310; GO:0016477; GO:0030168; GO:0030496; GO:0031526; GO:0033031; GO:0035005; GO:0035022; GO:0036092; GO:0040016; GO:0043231; GO:0043407; GO:0043560; GO:0046854; GO:0046934; GO:0048015; GO:0051000; GO:0051897; GO:0051898; GO:0052742; GO:0052812; GO:0060055; GO:0106310; GO:1900747; GO:1903298; GO:1903671 26913 XM_029336079.2 87 0 159 0 756 Q9US12 3.86e-22 Putative zinc metalloproteinase C607.06c (EC 3.4.24.-) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) proteolysis [GO:0006508] GO:0005634; GO:0005829; GO:0006508; GO:0008237; GO:0030246; GO:0032153; GO:0046872 26914 XM_044315999.1 2 0 9 4 11 NA NA NA NA NA NA 26915 XM_029351248.2 10 0 0 0 0 A8Y5U1 4.66e-42 RAB7A-interacting MON1-CCZ1 complex subunit 1 (UPF0600 protein C5orf51 homolog) Danio rerio (Zebrafish) (Brachydanio rerio) mitophagy [GO:0000423] GO:0000423; GO:0005829 26916 XM_029348733.2 0 0 0 8 12 NA NA NA NA NA NA 26917 XM_029331455.2 373 229 117 263 284 Q15427 8.43e-139 Splicing factor 3B subunit 4 (Pre-mRNA-splicing factor SF3b 49 kDa subunit) (Spliceosome-associated protein 49) (SAP 49) Homo sapiens (Human) mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]; U2-type prespliceosome assembly [GO:1903241] GO:0000375; GO:0000398; GO:0003723; GO:0005634; GO:0005654; GO:0005681; GO:0005684; GO:0005686; GO:0005689; GO:0006397; GO:0008380; GO:0048026; GO:0071005; GO:1903241; GO:1990935 26918 XM_029351507.2 144 40 48 76 141 NA NA NA NA NA NA 26919 XM_029346172.2 370 290 149 372 426 Q0VFM0 1.03e-79 Zinc finger protein-like 1 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) vesicle-mediated transport [GO:0016192] GO:0005794; GO:0016020; GO:0016192; GO:0046872 26920 XM_044312934.1 0 2 7 0 0 Q5RED7 1.29e-72 Acylglycerol kinase, mitochondrial (EC 2.7.1.107) (EC 2.7.1.138) (EC 2.7.1.94) (Multiple substrate lipid kinase) (MuLK) (Multi-substrate lipid kinase) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) ceramide biosynthetic process [GO:0046513]; glycerolipid metabolic process [GO:0046486]; protein insertion into mitochondrial inner membrane [GO:0045039] GO:0001729; GO:0004143; GO:0005524; GO:0005743; GO:0005758; GO:0031966; GO:0042721; GO:0045039; GO:0046486; GO:0046513; GO:0047620; GO:0102773 26921 XM_044309156.1 70 9 28 20 35 A7SFB5 4.36e-29 Cyclic GMP-AMP synthase (NvcGAS) (cGAMP synthase) (cGAS) (nv-cGAS) (EC 2.7.7.86) (3'3'-cGAMP synthase) Nematostella vectensis (Starlet sea anemone) NA GO:0005524; GO:0005525; GO:0005829; GO:0046872; GO:0061501 26922 XM_044323796.1 2581 2364 1490 2330 2373 Q14849 3.34e-50 StAR-related lipid transfer protein 3 (Metastatic lymph node gene 64 protein) (MLN 64) (Protein CAB1) (START domain-containing protein 3) (StARD3) Homo sapiens (Human) cholesterol metabolic process [GO:0008203]; cholesterol transport [GO:0030301]; lipid metabolic process [GO:0006629]; mitochondrial transport [GO:0006839]; progesterone biosynthetic process [GO:0006701]; steroid metabolic process [GO:0008202]; vesicle tethering to endoplasmic reticulum [GO:0099044] GO:0005654; GO:0005737; GO:0005739; GO:0005765; GO:0005768; GO:0005829; GO:0006629; GO:0006701; GO:0006839; GO:0008202; GO:0008203; GO:0015485; GO:0030301; GO:0031902; GO:0042803; GO:0043231; GO:0044232; GO:0099044; GO:0120020; GO:0140284 26923 XM_044326925.1 0 0 27 8 29 NA NA NA NA NA NA 26924 XM_044327321.1 0 28 9 0 0 NA NA NA NA NA NA 26925 XM_044313417.1 96 40 76 101 133 NA NA NA NA NA NA 26926 XM_029358521.2 245 363 181 166 153 NA NA NA NA NA NA 26927 XR_006393549.1 351 391 303 301 604 NA NA NA NA NA NA 26928 XM_029337136.2 2 6 11 4 13 NA NA NA NA NA NA 26929 XM_029343848.2 176 157 159 223 309 Q7Z4H7 1.59e-23 HAUS augmin-like complex subunit 6 Homo sapiens (Human) cell division [GO:0051301]; centrosome cycle [GO:0007098]; microtubule cytoskeleton organization [GO:0000226]; spindle assembly [GO:0051225] GO:0000226; GO:0005813; GO:0005829; GO:0007098; GO:0008017; GO:0051225; GO:0051301; GO:0070652; GO:1990498 26930 XM_044307350.1 6 0 1 558 16 NA NA NA NA NA NA 26931 XM_029344176.2 36 13 23 10 110 NA NA NA NA NA NA 26932 XM_044322453.1 106 0 107 2 223 NA NA NA NA NA NA 26933 XM_044311970.1 6 152 0 35 394 B8VIU6 7.48e-55 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 26934 XR_006393945.1 31 10 46 175 18 NA NA NA NA NA NA 26935 XM_044322892.1 0 3 1 44 25 NA NA NA NA NA NA 26936 XR_006393220.1 13 1 2 5 2 NA NA NA NA NA NA 26937 XM_029324133.2 100 45 21 119 131 A4IHR5 5.22e-55 Insulinoma-associated protein 1 (Zinc finger protein IA-1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) endocrine pancreas development [GO:0031018]; endodermal cell differentiation [GO:0035987]; gland development [GO:0048732]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; pancreatic A cell differentiation [GO:0003310]; transdifferentiation [GO:0060290]; type B pancreatic cell differentiation [GO:0003309] GO:0000122; GO:0000978; GO:0003309; GO:0003310; GO:0003700; GO:0005634; GO:0007399; GO:0017053; GO:0031018; GO:0031490; GO:0035987; GO:0046872; GO:0048732; GO:0060290 26938 XM_029323664.2 62 341 927 587 1083 Q2KIA4 4.86e-117 Stearoyl-CoA desaturase 5 (EC 1.14.19.1) (Acyl-CoA-desaturase 4) (Stearoyl-CoA 9-desaturase) Bos taurus (Bovine) monounsaturated fatty acid biosynthetic process [GO:1903966]; unsaturated fatty acid biosynthetic process [GO:0006636] GO:0004768; GO:0005506; GO:0005789; GO:0006636; GO:0016491; GO:1903966 26939 XM_029354490.2 0 51 26 11 10 NA NA NA NA NA NA 26940 XM_029354565.2 38 17 49 56 82 Q9M2U3 9.34e-29 Protein ALP1-like (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) NA GO:0000118; GO:0004518; GO:0046872 26941 XR_003825364.2 16 54 11 13 66 NA NA NA NA NA NA 26942 XM_029327217.2 217 0 97 195 115 P47736 2.25e-113 Rap1 GTPase-activating protein 1 (Rap1GAP) (Rap1GAP1) Homo sapiens (Human) activation of GTPase activity [GO:0090630]; adaptive immune response [GO:0002250]; cellular response to glial cell derived neurotrophic factor [GO:1990792]; negative regulation of GTP binding [GO:1904425]; negative regulation of microvillus assembly [GO:1903697]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of thyroid gland epithelial cell proliferation [GO:1904442]; positive regulation of GTPase activity [GO:0043547]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] GO:0000139; GO:0002250; GO:0003924; GO:0005096; GO:0005737; GO:0005769; GO:0005829; GO:0007165; GO:0016020; GO:0030424; GO:0030425; GO:0031267; GO:0042803; GO:0043025; GO:0043087; GO:0043547; GO:0045665; GO:0051056; GO:0090630; GO:1903697; GO:1904425; GO:1904442; GO:1990792 26943 XR_006394686.1 0 0 9 3 21 NA NA NA NA NA NA 26944 XR_006393229.1 118 134 99 114 165 NA NA NA NA NA NA 26945 XM_044308827.1 0 4 15 46 0 NA NA NA NA NA NA 26946 XR_003824249.2 234 231 113 403 370 NA NA NA NA NA NA 26947 XM_029350790.1 3419 3475 2476 4063 4031 A2VDZ9 7.41e-59 Vesicle-associated membrane protein-associated protein B (VAMP-B) (VAMP-associated protein B) (VAP-B) Bos taurus (Bovine) cellular calcium ion homeostasis [GO:0006874]; endoplasmic reticulum membrane organization [GO:0090158]; endoplasmic reticulum-plasma membrane tethering [GO:0061817]; IRE1-mediated unfolded protein response [GO:0036498] GO:0005789; GO:0005886; GO:0006874; GO:0033149; GO:0036498; GO:0061817; GO:0090158 26948 XM_029341433.2 3919 3282 1888 4102 2287 NA NA NA NA NA NA 26949 XM_029332058.2 4140 3300 2515 3290 3195 Q61792 2.46e-72 LIM and SH3 domain protein 1 (LASP-1) (Metastatic lymph node gene 50 protein) (MLN 50) Mus musculus (Mouse) ion transport [GO:0006811] GO:0005737; GO:0005925; GO:0006811; GO:0015075; GO:0030864; GO:0046872; GO:0051015; GO:0098794 26950 XM_029348055.2 1343 1281 603 1283 1021 Q7Z6M1 3.81e-92 Rab9 effector protein with kelch motifs (40 kDa Rab9 effector protein) (p40) Homo sapiens (Human) receptor-mediated endocytosis [GO:0006898]; vesicle docking involved in exocytosis [GO:0006904] GO:0005768; GO:0005829; GO:0006898; GO:0006904; GO:0010008; GO:0030133; GO:0032588 26951 XM_044308274.1 2 5 11 2 55 NA NA NA NA NA NA 26952 XM_044326606.1 0 0 6 0 0 Q91ZV7 2.31e-51 Plexin domain-containing protein 1 (Tumor endothelial marker 7) Mus musculus (Mouse) spinal cord development [GO:0021510] GO:0005737; GO:0005886; GO:0005923; GO:0021510; GO:0030425; GO:0043025; GO:0043235 26953 XM_044328737.1 176 159 213 225 399 Q96AY4 6.74e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26954 XM_044328737.1 176 159 213 225 399 Q96AY4 6.23e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26955 XM_044328737.1 176 159 213 225 399 Q96AY4 7.23e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26956 XM_044328737.1 176 159 213 225 399 Q96AY4 1.52e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26957 XM_044322757.1 661 451 1065 1348 605 Q8LQJ9 0 ATP-dependent zinc metalloprotease FTSH 4, mitochondrial (OsFTSH4) (EC 3.4.24.-) Oryza sativa subsp. japonica (Rice) proteolysis [GO:0006508] GO:0004176; GO:0004222; GO:0005524; GO:0005739; GO:0006508; GO:0009534; GO:0016020; GO:0016887; GO:0046872 26958 XM_044322441.1 191 165 314 137 379 Q8K4H1 3.47e-68 Kynurenine formamidase (KFA) (KFase) (EC 3.5.1.9) (Arylformamidase) (N-formylkynurenine formamidase) (FKF) Mus musculus (Mouse) 'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; tryptophan catabolic process to kynurenine [GO:0019441] GO:0004061; GO:0005634; GO:0005737; GO:0005829; GO:0019441; GO:0034354 26959 XM_029350652.2 391 225 329 551 581 Q6DG36 4.05e-132 Proton-coupled zinc antiporter SLC30A5 (Solute carrier family 30 member 5) (Zinc transporter 5) (ZnT-5) Danio rerio (Zebrafish) (Brachydanio rerio) cellular zinc ion homeostasis [GO:0006882]; GPI anchor biosynthetic process [GO:0006506]; metal ion transport [GO:0030001]; response to zinc ion [GO:0010043]; zinc ion import into Golgi lumen [GO:1904257]; zinc ion import into organelle [GO:0062111]; zinc ion transport [GO:0006829] GO:0000139; GO:0005385; GO:0005789; GO:0005794; GO:0006506; GO:0006829; GO:0006882; GO:0010043; GO:0012507; GO:0030001; GO:0030667; GO:0031410; GO:0032588; GO:0046872; GO:0046873; GO:0062111; GO:0140826; GO:1904257; GO:1990674 26960 XM_029350652.2 391 225 329 551 581 Q6DG36 5.44e-49 Proton-coupled zinc antiporter SLC30A5 (Solute carrier family 30 member 5) (Zinc transporter 5) (ZnT-5) Danio rerio (Zebrafish) (Brachydanio rerio) cellular zinc ion homeostasis [GO:0006882]; GPI anchor biosynthetic process [GO:0006506]; metal ion transport [GO:0030001]; response to zinc ion [GO:0010043]; zinc ion import into Golgi lumen [GO:1904257]; zinc ion import into organelle [GO:0062111]; zinc ion transport [GO:0006829] GO:0000139; GO:0005385; GO:0005789; GO:0005794; GO:0006506; GO:0006829; GO:0006882; GO:0010043; GO:0012507; GO:0030001; GO:0030667; GO:0031410; GO:0032588; GO:0046872; GO:0046873; GO:0062111; GO:0140826; GO:1904257; GO:1990674 26961 XM_029350585.2 148 34 81 38 58 Q6PIW4 2.75e-174 Fidgetin-like protein 1 (EC 3.6.4.-) Homo sapiens (Human) ATP metabolic process [GO:0046034]; cellular response to ionizing radiation [GO:0071479]; male meiotic nuclear division [GO:0007140]; negative regulation of apoptotic process [GO:0043066]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; regulation of cell cycle [GO:0051726]; regulation of double-strand break repair via homologous recombination [GO:0010569] GO:0000228; GO:0000287; GO:0001649; GO:0005524; GO:0005634; GO:0005737; GO:0007140; GO:0008568; GO:0010569; GO:0016787; GO:0016887; GO:0033687; GO:0043066; GO:0046034; GO:0048471; GO:0051726; GO:0070062; GO:0071479; GO:2001243 26962 XM_044312197.1 36 34 3 26 65 Q94K49 1.63e-50 Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1 (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) epigenetic regulation of gene expression [GO:0040029] GO:0003682; GO:0004518; GO:0005634; GO:0035098; GO:0035102; GO:0040029; GO:0046872 26963 XR_006396566.1 0 0 0 0 9 NA NA NA NA NA NA 26964 XM_029350181.2 1279 694 655 1989 1375 Q14AW5 8.85e-59 Putative methyltransferase NSUN7 (EC 2.1.1.-) (NOL1/NOP2/Sun domain family member 7) Mus musculus (Mouse) flagellated sperm motility [GO:0030317]; methylation [GO:0032259]; sperm mitochondrion organization [GO:0030382] GO:0003723; GO:0008168; GO:0030317; GO:0030382; GO:0032259 26965 XM_044318401.1 14 1 0 0 5 NA NA NA NA NA NA 26966 XM_044327151.1 699 143 244 703 458 B8VIW9 0 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 26967 XM_029333798.2 295 174 110 253 218 Q91ZN5 4.05e-114 Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (PAPS transporter 1) (Solute carrier family 35 member B2) Mus musculus (Mouse) 3'-phosphoadenosine 5'-phosphosulfate transport [GO:0046963] GO:0000139; GO:0005789; GO:0005794; GO:0016020; GO:0022857; GO:0046963; GO:0046964 26968 XM_044314701.1 67 6 49 122 0 NA NA NA NA NA NA 26969 XM_044320323.1 0 0 17 160 11 NA NA NA NA NA NA 26970 XR_006391704.1 70 115 27 44 60 NA NA NA NA NA NA 26971 XR_006392920.1 41 2 25 5 151 NA NA NA NA NA NA 26972 XM_044314813.1 0 0 0 78 0 NA NA NA NA NA NA 26973 XM_044308321.1 13 0 0 5 7 NA NA NA NA NA NA 26974 XM_044314679.1 56 59 10 23 56 NA NA NA NA NA NA 26975 XM_044320679.1 98 9 20 10 33 NA NA NA NA NA NA 26976 XR_006394639.1 28 18 1 24 28 NA NA NA NA NA NA 26977 XM_029355859.2 32 12 13 4 5 Q4AE28 3.38e-37 Doublesex- and mab-3-related transcription factor A2 (Doublesex- and mab-3-related transcription factor 5) Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006355; GO:0043565; GO:0046872 26978 XM_044310255.1 0 19 14 0 2 Q09575 1e-46 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 26979 XM_044310142.1 25 15 41 29 19 NA NA NA NA NA NA 26980 XM_044309469.1 0 0 0 9 6 O70165 4.12e-76 Ficolin-1 (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin-alpha) (M-ficolin) Mus musculus (Mouse) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation, lectin pathway [GO:0001867]; G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of interleukin-8 production [GO:0032757] GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005581; GO:0005615; GO:0007186; GO:0030246; GO:0031232; GO:0032757; GO:0038187; GO:0046872; GO:0062023; GO:0097367 26981 XM_044325217.1 22 0 37 8 0 P47972 2.71e-23 Neuronal pentraxin-2 (NP2) (Neuronal pentraxin II) (NP-II) Homo sapiens (Human) associative learning [GO:0008306]; chemical synaptic transmission [GO:0007268]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962] GO:0005576; GO:0007268; GO:0008306; GO:0030246; GO:0046872; GO:0098962; GO:0098978 26982 XR_006398177.1 917 362 524 896 1263 Q8C033 8.34e-22 Rho guanine nucleotide exchange factor 10 Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; activation of GTPase activity [GO:0090630]; centrosome duplication [GO:0051298]; mitotic spindle assembly [GO:0090307]; myelination in peripheral nervous system [GO:0022011]; positive regulation of stress fiber assembly [GO:0051496] GO:0005085; GO:0005813; GO:0019894; GO:0022011; GO:0030036; GO:0051298; GO:0051496; GO:0090307; GO:0090630 26983 XR_006396891.1 0 0 0 0 28 NA NA NA NA NA NA 26984 XR_006394665.1 44 0 2 24 6 NA NA NA NA NA NA 26985 XM_029344723.2 0 0 200 264 6 Q5R2J4 6.9e-76 Protein APCDD1 (Adenomatosis polyposis coli down-regulated 1 protein homolog) (PsAPCDD1) Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis) negative regulation of Wnt signaling pathway [GO:0030178]; Wnt signaling pathway [GO:0016055] GO:0005615; GO:0005886; GO:0016055; GO:0017147; GO:0030178 26986 XM_044315829.1 56 25 0 1 23 NA NA NA NA NA NA 26987 XM_044313265.1 0 0 3 0 24 A0A1L8FDW4 1.29e-40 Peroxisomal targeting signal 1 receptor (PTS1 receptor) (PTS1R) (PTS1-BP) (Peroxin-5) Xenopus laevis (African clawed frog) pexophagy [GO:0000425]; protein import into peroxisome matrix, receptor recycling [GO:0016562]; protein import into peroxisome matrix, substrate release [GO:0044721]; protein import into peroxisome matrix, translocation [GO:0016561] GO:0000425; GO:0005052; GO:0005782; GO:0005829; GO:0016561; GO:0016562; GO:0044721; GO:0140597 26988 XM_029339480.2 904 211 377 563 212 Q91827 3.67e-23 Apoptosis regulator R1 (XR1) Xenopus laevis (African clawed frog) apoptotic process [GO:0006915]; regulation of apoptotic process [GO:0042981] GO:0006915; GO:0016020; GO:0042981 26989 XM_029341604.2 847 31 324 642 39 NA NA NA NA NA NA 26990 XM_044311078.1 157 289 117 4 87 B2RXR6 1.09e-26 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (PP6-ARS-B) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-B) (Ankyrin repeat domain-containing protein 44) Mus musculus (Mouse) NA NA 26991 XM_044319917.1 251 151 323 151 352 Q9H7H0 4.22e-75 Methyltransferase-like protein 17, mitochondrial (EC 2.1.1.-) (False p73 target gene protein) (Methyltransferase 11 domain-containing protein 1) (Protein RSM22 homolog, mitochondrial) Homo sapiens (Human) methylation [GO:0032259]; ribosomal small subunit biogenesis [GO:0042274]; translation [GO:0006412] GO:0005654; GO:0005759; GO:0006412; GO:0008168; GO:0032259; GO:0042274; GO:1904047 26992 XM_029350521.2 74 33 63 137 96 A0NLY7 4.18e-25 Isatin hydrolase (EC 3.5.2.20) (Isatin amidohydrolase) (Isatin hydrolase isoform b) (IH-b) Roseibium aggregatum (strain ATCC 25650 / DSM 13394 / JCM 20685 / NBRC 16684 / NCIMB 2208 / IAM 12614 / B1) (Stappia aggregata) tryptophan catabolic process to kynurenine [GO:0019441] GO:0004061; GO:0016812; GO:0019441; GO:0030145 26993 XM_029331823.2 931 803 694 812 859 Q5ZK10 1.32e-101 NSFL1 cofactor p47 (p97 cofactor p47) Gallus gallus (Chicken) autophagosome assembly [GO:0000045]; establishment of mitotic spindle orientation [GO:0000132]; Golgi organization [GO:0007030]; membrane fusion [GO:0061025]; negative regulation of protein localization to centrosome [GO:1904780]; nuclear membrane reassembly [GO:0031468]; positive regulation of mitotic centrosome separation [GO:0046604]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] GO:0000045; GO:0000132; GO:0005634; GO:0005795; GO:0005815; GO:0005829; GO:0007030; GO:0008289; GO:0031468; GO:0043130; GO:0043161; GO:0046604; GO:0061025; GO:1904780; GO:1990730 26994 XM_029356274.2 0 0 21 0 9 Q6P832 0 Glycine amidinotransferase, mitochondrial (EC 2.1.4.1) (L-arginine:glycine amidinotransferase) (Transamidinase) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) creatine biosynthetic process [GO:0006601] GO:0005743; GO:0006601; GO:0015068 26995 XM_044316403.1 292 229 118 21 5 NA NA NA NA NA NA 26996 XM_044323038.1 1196 1046 510 1405 282 Q6P1L5 5.82e-25 Protein FAM117B (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 13 protein) Homo sapiens (Human) NA NA 26997 XM_029342095.2 1029 599 518 556 561 Q3USF0 6.72e-35 Acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase (EC 2.4.1.147) (Core 3 synthase) (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6) (BGnT-6) (Beta-1,3-Gn-T6) (Beta-1,3-N-acetylglucosaminyltransferase 6) (Beta3Gn-T6) Mus musculus (Mouse) poly-N-acetyllactosamine biosynthetic process [GO:0030311]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0008194; GO:0008378; GO:0016757; GO:0030311; GO:0106327; GO:0106328 26998 XM_029348556.2 548 140 246 86 123 Q9Z139 2.16e-123 Inactive tyrosine-protein kinase transmembrane receptor ROR1 (mROR1) (Neurotrophic tyrosine kinase, receptor-related 1) Mus musculus (Mouse) astrocyte development [GO:0014002]; inner ear development [GO:0048839]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of kinase activity [GO:0033674]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; sensory perception of sound [GO:0007605] GO:0001725; GO:0004714; GO:0005524; GO:0005737; GO:0005886; GO:0007605; GO:0009986; GO:0010976; GO:0014002; GO:0014068; GO:0017147; GO:0033674; GO:0042813; GO:0043123; GO:0043235; GO:0043679; GO:0048839; GO:0051092 26999 XM_044318865.1 61 52 0 0 0 P97393 0 Rho GTPase-activating protein 5 (Rho-type GTPase-activating protein 5) (p190-B) Mus musculus (Mouse) cell migration [GO:0016477]; epithelial cell migration [GO:0010631]; mammary gland development [GO:0030879]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of mesenchymal cell proliferation [GO:0002053]; regulation of cell size [GO:0008361]; Rho protein signal transduction [GO:0007266] GO:0002053; GO:0003924; GO:0005096; GO:0005525; GO:0005783; GO:0005829; GO:0005886; GO:0007266; GO:0008361; GO:0010631; GO:0010634; GO:0016477; GO:0030879; GO:0042169 27000 XM_044318865.1 61 52 0 0 0 P97393 1.77e-35 Rho GTPase-activating protein 5 (Rho-type GTPase-activating protein 5) (p190-B) Mus musculus (Mouse) cell migration [GO:0016477]; epithelial cell migration [GO:0010631]; mammary gland development [GO:0030879]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of mesenchymal cell proliferation [GO:0002053]; regulation of cell size [GO:0008361]; Rho protein signal transduction [GO:0007266] GO:0002053; GO:0003924; GO:0005096; GO:0005525; GO:0005783; GO:0005829; GO:0005886; GO:0007266; GO:0008361; GO:0010631; GO:0010634; GO:0016477; GO:0030879; GO:0042169 27001 XM_044307800.1 0 22 0 0 0 Q7RTR2 1.06e-49 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 27002 XM_044307800.1 0 22 0 0 0 Q7RTR2 2.17e-49 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 27003 XM_044307800.1 0 22 0 0 0 Q7RTR2 1.52e-48 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 27004 XM_044307800.1 0 22 0 0 0 Q7RTR2 2.39e-45 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 27005 XM_044307800.1 0 22 0 0 0 Q7RTR2 5.02e-42 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 27006 XM_044307800.1 0 22 0 0 0 Q7RTR2 1.86e-36 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 27007 XM_044307800.1 0 22 0 0 0 Q7RTR2 3.18e-31 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 27008 XR_003823467.2 24 3 6 15 13 NA NA NA NA NA NA 27009 XM_044318070.1 6 76 44 152 218 NA NA NA NA NA NA 27010 XM_044323684.1 65 1 125 146 0 NA NA NA NA NA NA 27011 XM_029333720.2 758 354 461 729 1029 Q9H2M9 0 Rab3 GTPase-activating protein non-catalytic subunit (RGAP-iso) (Rab3 GTPase-activating protein 150 kDa subunit) (Rab3-GAP p150) (Rab3-GAP150) (Rab3-GAP regulatory subunit) Homo sapiens (Human) establishment of protein localization to endoplasmic reticulum membrane [GO:0097051]; intracellular protein transport [GO:0006886]; positive regulation of autophagosome assembly [GO:2000786]; positive regulation of endoplasmic reticulum tubular network organization [GO:1903373]; positive regulation of protein lipidation [GO:1903061]; regulation of GTPase activity [GO:0043087] GO:0005096; GO:0005789; GO:0005829; GO:0005886; GO:0006886; GO:0008047; GO:0030234; GO:0031267; GO:0032991; GO:0043087; GO:0097051; GO:1903061; GO:1903373; GO:2000786 27012 XM_044311664.1 814 491 307 852 1013 NA NA NA NA NA NA 27013 XM_029324413.2 101 42 17 97 57 Q96KN3 4.89e-43 Homeobox protein PKNOX2 (Homeobox protein PREP-2) (PBX/knotted homeobox 2) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0003785; GO:0005654; GO:0005737; GO:0006357; GO:0015629; GO:0015630; GO:0045171; GO:0051015; GO:1990837 27014 XM_029324413.2 101 42 17 97 57 Q96KN3 8.56e-41 Homeobox protein PKNOX2 (Homeobox protein PREP-2) (PBX/knotted homeobox 2) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0003785; GO:0005654; GO:0005737; GO:0006357; GO:0015629; GO:0015630; GO:0045171; GO:0051015; GO:1990837 27015 XM_029344478.2 243 177 318 277 223 O62714 4.98e-123 Extracellular calcium-sensing receptor (CaSR) (Parathyroid cell calcium-sensing receptor) (PCaR1) Sus scrofa (Pig) cellular calcium ion homeostasis [GO:0006874]; detection of calcium ion [GO:0005513]; G protein-coupled receptor signaling pathway [GO:0007186]; regulation of calcium ion transport [GO:0051924] GO:0004930; GO:0005509; GO:0005513; GO:0005886; GO:0006874; GO:0007186; GO:0016597; GO:0042803; GO:0051924 27016 XM_029337038.2 3 0 14 0 2 NA NA NA NA NA NA 27017 XM_029351475.2 88 55 54 73 103 P21927 3.14e-99 Cholinesterase (EC 3.1.1.8) (Acylcholine acylhydrolase) (Butyrylcholine esterase) (Choline esterase II) (Pseudocholinesterase) Oryctolagus cuniculus (Rabbit) NA GO:0003990; GO:0004104; GO:0005576 27018 XR_006397450.1 2 2 9 7 46 NA NA NA NA NA NA 27019 XM_044318171.1 1198 921 949 1432 751 O14562 1.13e-107 Ubiquitin domain-containing protein UBFD1 (Ubiquitin-binding protein homolog) Homo sapiens (Human) NA GO:0003723; GO:0045296 27020 XM_029358623.2 180 36 109 228 219 Q8SZA8 7.91e-35 Adrenodoxin-like protein 2, mitochondrial (Ferredoxin-2) Drosophila melanogaster (Fruit fly) electron transport chain [GO:0022900]; P450-containing electron transport chain [GO:0140647]; positive regulation of ecdysteroid biosynthetic process [GO:0045998]; positive regulation of oxidoreductase activity [GO:0051353]; steroid biosynthetic process [GO:0006694] GO:0005739; GO:0006694; GO:0009055; GO:0022900; GO:0045998; GO:0046872; GO:0051353; GO:0051537; GO:0140647 27021 XM_029327178.2 260 179 202 238 166 NA NA NA NA NA NA 27022 XM_044322389.1 11 34 59 66 68 NA NA NA NA NA NA 27023 XM_044321479.1 74 105 63 171 123 NA NA NA NA NA NA 27024 XM_029339902.2 1663 2217 1519 3351 2582 Q8BJH1 6.3e-33 Zinc finger C2HC domain-containing protein 1A Mus musculus (Mouse) NA GO:0046872 27025 XM_044324734.1 23 2 8 35 35 P97343 8.04e-28 Serine/threonine-protein kinase Kist (EC 2.7.11.1) (Kinase interacting with stathmin) (PAM COOH-terminal interactor protein 2) (P-CIP2) (U2AF homology motif kinase 1) Mus musculus (Mouse) neuron projection development [GO:0031175]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of translational initiation [GO:0045948]; protein autophosphorylation [GO:0046777]; regulation of cell cycle [GO:0051726]; regulation of protein export from nucleus [GO:0046825] GO:0003723; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0016607; GO:0018105; GO:0019899; GO:0030424; GO:0031175; GO:0032839; GO:0043021; GO:0043231; GO:0045948; GO:0046777; GO:0046825; GO:0051726; GO:0071598; GO:0106310; GO:1990935 27026 XM_029344874.2 1889 1447 705 1120 1174 Q9CXF4 1.8e-143 TBC1 domain family member 15 (GTPase-activating protein RAB7) (GAP for RAB7) (Rab7-GAP) Mus musculus (Mouse) activation of GTPase activity [GO:0090630]; regulation of GTPase activity [GO:0043087] GO:0005096; GO:0005576; GO:0005737; GO:0005739; GO:0043087; GO:0090630 27027 XM_029344218.2 0 12 0 3 2 O95263 0 High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B (HsPDE8B) (EC 3.1.4.53) (Cell proliferation-inducing gene 22 protein) Homo sapiens (Human) behavioral fear response [GO:0001662]; cAMP catabolic process [GO:0006198]; negative regulation of steroid hormone biosynthetic process [GO:0090032]; neuromuscular process controlling balance [GO:0050885]; operant conditioning [GO:0035106]; signal transduction [GO:0007165]; visual learning [GO:0008542] GO:0001662; GO:0004114; GO:0004115; GO:0005829; GO:0006198; GO:0007165; GO:0008542; GO:0035106; GO:0046872; GO:0050885; GO:0090032 27028 XM_029346124.2 2999 1827 1694 2290 1665 NA NA NA NA NA NA 27029 XM_044319461.1 0 0 20 6 3 NA NA NA NA NA NA 27030 XM_044327564.1 60 68 87 193 158 NA NA NA NA NA NA 27031 XM_044306963.1 836 383 232 736 466 B8V7S0 1.01e-168 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 27032 XM_044306963.1 836 383 232 736 466 B8V7S0 1.85e-26 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 27033 XM_029356032.2 80 17 0 0 30 Q08CX1 1.54e-65 Ras and EF-hand domain-containing protein Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0003924; GO:0005509; GO:0005525; GO:0048471 27034 XM_029356032.2 80 17 0 0 30 Q08CX1 2.85e-28 Ras and EF-hand domain-containing protein Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0003924; GO:0005509; GO:0005525; GO:0048471 27035 XR_003825053.2 1774 278 572 1541 1027 NA NA NA NA NA NA 27036 XM_044310566.1 0 0 0 0 13 NA NA NA NA NA NA 27037 XM_044314002.1 89 201 100 179 54 A6NE52 1e-69 WD repeat-containing protein 97 Homo sapiens (Human) NA NA 27038 XM_029336962.2 256 102 134 235 288 NA NA NA NA NA NA 27039 XM_044323859.1 505 730 589 1071 753 Q8K3Z0 7.24e-30 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 27040 XM_044309475.1 2 0 91 0 1 NA NA NA NA NA NA 27041 XM_029340635.2 15287 19872 13099 15426 10381 Q78IS1 2.84e-72 Transmembrane emp24 domain-containing protein 3 (p24 family protein gamma-4) (p24gamma4) Mus musculus (Mouse) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886] GO:0005783; GO:0005789; GO:0005793; GO:0005794; GO:0006886; GO:0006888; GO:0007030; GO:0030126; GO:0030134; GO:0032580; GO:0033116 27042 XM_044318854.1 2828 1275 1320 3320 2093 O57314 6.1e-84 Very-long-chain 3-oxoacyl-CoA reductase (EC 1.1.1.330) (17-beta-hydroxysteroid dehydrogenase 12) (17-beta-HSD 12) (3-ketoacyl-CoA reductase) (KAR) (Estradiol 17-beta-dehydrogenase 12) (EC 1.1.1.62) Anas platyrhynchos (Mallard) (Anas boschas) estrogen biosynthetic process [GO:0006703]; fatty acid biosynthetic process [GO:0006633] GO:0005789; GO:0006633; GO:0006703; GO:0044594; GO:0102339; GO:0102340; GO:0102341; GO:0102342 27043 XM_029340473.2 58 0 18 121 174 Q15811 4.15e-23 Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17) Homo sapiens (Human) clathrin-dependent synaptic vesicle endocytosis [GO:0150007]; endocytosis [GO:0006897]; endosomal transport [GO:0016197]; exocytosis [GO:0006887]; intracellular signal transduction [GO:0035556]; protein localization [GO:0008104]; protein transport [GO:0015031]; regulation of small GTPase mediated signal transduction [GO:0051056] GO:0005085; GO:0005509; GO:0005635; GO:0005737; GO:0005829; GO:0005886; GO:0005905; GO:0006887; GO:0006897; GO:0008104; GO:0015031; GO:0016197; GO:0030027; GO:0035556; GO:0043005; GO:0051056; GO:0055037; GO:0060090; GO:0070064; GO:0098793; GO:0150007 27044 XM_029335932.2 5009 9285 15562 1968 42 NA NA NA NA NA NA 27045 XM_044308423.1 2722 3356 827 2440 2700 NA NA NA NA NA NA 27046 XM_044328476.1 38 10 4 0 125 O42127 2.4e-43 Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) Xenopus laevis (African clawed frog) apoptotic process [GO:0006915]; positive regulation of cell population proliferation [GO:0008284] GO:0005007; GO:0005524; GO:0005886; GO:0006915; GO:0008284 27047 XR_006392434.1 0 0 5 2 8 P83858 7.63e-28 Pyroglutamylated RF-amide peptide receptor (AQ27) (G-protein coupled receptor 103) (Orexigenic neuropeptide QRFP receptor) (SP9155) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:0097730 27048 XM_029329707.2 23 12 34 31 9 F4IF36 2.43e-119 Protein FORGETTER 1 (Protein EMBRYO DEFECTIVE 1135) Arabidopsis thaliana (Mouse-ear cress) chromatin remodeling [GO:0006338]; epigenetic regulation of gene expression [GO:0040029]; heat acclimation [GO:0010286]; positive regulation of cellular response to heat [GO:1900036]; regulation of DNA-templated transcription [GO:0006355]; response to heat [GO:0009408] GO:0005634; GO:0006338; GO:0006355; GO:0009408; GO:0010286; GO:0031490; GO:0040029; GO:0042393; GO:0046872; GO:1900036; GO:1990841 27049 XM_029329707.2 23 12 34 31 9 F4IF36 1.85e-103 Protein FORGETTER 1 (Protein EMBRYO DEFECTIVE 1135) Arabidopsis thaliana (Mouse-ear cress) chromatin remodeling [GO:0006338]; epigenetic regulation of gene expression [GO:0040029]; heat acclimation [GO:0010286]; positive regulation of cellular response to heat [GO:1900036]; regulation of DNA-templated transcription [GO:0006355]; response to heat [GO:0009408] GO:0005634; GO:0006338; GO:0006355; GO:0009408; GO:0010286; GO:0031490; GO:0040029; GO:0042393; GO:0046872; GO:1900036; GO:1990841 27050 XM_029348604.2 0 0 0 81 0 A6U882 4.85e-23 30S ribosomal protein S11 Sinorhizobium medicae (strain WSM419) (Ensifer medicae) translation [GO:0006412] GO:0003735; GO:0005840; GO:0006412; GO:0019843; GO:1990904 27051 XM_029340057.2 88 110 55 172 77 P83852 6.18e-139 Carboxypeptidase D (EC 3.4.17.22) (CPD-2) (Metallocarboxypeptidase D) Lophonetta specularioides (Crested duck) (Anas specularioides) proteolysis [GO:0006508] GO:0004181; GO:0006508; GO:0008270; GO:0016020 27052 XM_044312840.1 402 375 142 263 351 NA NA NA NA NA NA 27053 XM_029346268.2 4056 2182 1722 3289 2514 P36897 9.61e-163 TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (Activin A receptor type II-like protein kinase of 53kD) (Activin receptor-like kinase 5) (ALK-5) (ALK5) (Serine/threonine-protein kinase receptor R4) (SKR4) (TGF-beta type I receptor) (Transforming growth factor-beta receptor type I) (TGF-beta receptor type I) (TbetaR-I) Homo sapiens (Human) activin receptor signaling pathway [GO:0032924]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; anterior/posterior pattern specification [GO:0009952]; apoptotic process [GO:0006915]; artery morphogenesis [GO:0048844]; blastocyst development [GO:0001824]; cardiac epithelial to mesenchymal transition [GO:0060317]; cell motility [GO:0048870]; cellular response to growth factor stimulus [GO:0071363]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen fibril organization [GO:0030199]; coronary artery morphogenesis [GO:0060982]; embryonic cranial skeleton morphogenesis [GO:0048701]; endothelial cell activation [GO:0042118]; endothelial cell migration [GO:0043542]; endothelial cell proliferation [GO:0001935]; epicardium morphogenesis [GO:1905223]; epithelial to mesenchymal transition [GO:0001837]; extracellular structure organization [GO:0043062]; filopodium assembly [GO:0046847]; germ cell migration [GO:0008354]; heart development [GO:0007507]; in utero embryonic development [GO:0001701]; intracellular signal transduction [GO:0035556]; kidney development [GO:0001822]; lens development in camera-type eye [GO:0002088]; male gonad development [GO:0008584]; mesenchymal cell differentiation [GO:0048762]; negative regulation of chondrocyte differentiation [GO:0032331]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; nervous system development [GO:0007399]; neuron fate commitment [GO:0048663]; parathyroid gland development [GO:0060017]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; pharyngeal system development [GO:0060037]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation [GO:1905007]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of tight junction disassembly [GO:1905075]; post-embryonic development [GO:0009791]; protein phosphorylation [GO:0006468]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of cell cycle [GO:0051726]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gene expression [GO:0010468]; regulation of protein binding [GO:0043393]; regulation of protein ubiquitination [GO:0031396]; response to cholesterol [GO:0070723]; roof of mouth development [GO:0060021]; signal transduction [GO:0007165]; skeletal system development [GO:0001501]; skeletal system morphogenesis [GO:0048705]; thymus development [GO:0048538]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ventricular compact myocardium morphogenesis [GO:0003223]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222]; wound healing [GO:0042060] GO:0001501; GO:0001701; GO:0001822; GO:0001824; GO:0001837; GO:0001935; GO:0001937; GO:0001938; GO:0002088; GO:0003222; GO:0003223; GO:0004672; GO:0004674; GO:0005024; GO:0005025; GO:0005114; GO:0005524; GO:0005634; GO:0005768; GO:0005886; GO:0005923; GO:0006355; GO:0006468; GO:0006915; GO:0007165; GO:0007179; GO:0007399; GO:0007507; GO:0008284; GO:0008354; GO:0008584; GO:0009791; GO:0009952; GO:0009986; GO:0010468; GO:0010628; GO:0010717; GO:0010718; GO:0010862; GO:0016020; GO:0016361; GO:0018105; GO:0018107; GO:0030199; GO:0030307; GO:0030335; GO:0031396; GO:0032331; GO:0032924; GO:0035556; GO:0042060; GO:0042118; GO:0043062; GO:0043235; GO:0043393; GO:0043410; GO:0043542; GO:0045121; GO:0045893; GO:0046332; GO:0046847; GO:0046872; GO:0048179; GO:0048185; GO:0048538; GO:0048663; GO:0048701; GO:0048705; GO:0048762; GO:0048844; GO:0048870; GO:0050431; GO:0051491; GO:0051496; GO:0051726; GO:0051897; GO:0060017; GO:0060021; GO:0060037; GO:0060043; GO:0060317; GO:0060389; GO:0060391; GO:0060412; GO:0060978; GO:0060982; GO:0070021; GO:0070411; GO:0070723; GO:0071363; GO:0071560; GO:1905007; GO:1905075; GO:1905223; GO:2001235; GO:2001237 27054 XM_029338418.2 2043 2292 1408 2003 1748 P62323 5.43e-49 Small nuclear ribonucleoprotein Sm D3 (Sm-D3) (snRNP core protein D3) Xenopus laevis (African clawed frog) mRNA splicing, via spliceosome [GO:0000398]; spliceosomal snRNP assembly [GO:0000387] GO:0000387; GO:0000398; GO:0005634; GO:0005685; GO:0005687; GO:0005829; GO:0034709; GO:0034715; GO:0034719; GO:0046540; GO:0071005; GO:0071007; GO:0071208 27055 XM_044326124.1 157 13 18 27 26 NA NA NA NA NA NA 27056 XM_044315026.1 758 642 531 877 795 O57321 1.19e-129 Excitatory amino acid transporter 1 (SEAAT1) (Sodium-dependent glutamate/aspartate transporter) (GLAST) Ambystoma tigrinum (Eastern tiger salamander) chloride transmembrane transport [GO:1902476]; D-aspartate import across plasma membrane [GO:0070779]; L-aspartate import across plasma membrane [GO:0140009]; L-glutamate import across plasma membrane [GO:0098712]; potassium ion transmembrane transport [GO:0071805] GO:0005314; GO:0005886; GO:0015501; GO:0046872; GO:0070779; GO:0071805; GO:0098712; GO:0140009; GO:1902476 27057 XM_029335479.2 216 277 94 229 168 NA NA NA NA NA NA 27058 XM_044326222.1 0 28 2 6 0 NA NA NA NA NA NA 27059 XM_029346679.2 540 351 231 538 551 Q568K5 9.24e-65 N-alpha-acetyltransferase 40 (EC 2.3.1.257) (N-acetyltransferase 11) (N-alpha-acetyltransferase D) (NatD) Danio rerio (Zebrafish) (Brachydanio rerio) histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967] GO:0005634; GO:0005737; GO:0010485; GO:0043967; GO:0043968; GO:0043998; GO:1990189 27060 XM_029358684.2 257 195 343 99 268 P83038 0 Histone deacetylase 4 (HD4) (EC 3.5.1.98) Gallus gallus (Chicken) B cell activation [GO:0042113]; B cell differentiation [GO:0030183]; chromatin organization [GO:0006325]; histone deacetylation [GO:0016575]; histone H4 deacetylation [GO:0070933]; inflammatory response [GO:0006954]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of striated muscle tissue development [GO:0045843]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399] GO:0000118; GO:0000122; GO:0004407; GO:0005737; GO:0006325; GO:0006954; GO:0007399; GO:0016575; GO:0030183; GO:0042113; GO:0045843; GO:0045892; GO:0046872; GO:0070933; GO:0140297 27061 XR_006394262.1 11 4 43 9 189 NA NA NA NA NA NA 27062 XM_044319383.1 198 48 66 195 94 Q6YHK3 0 CD109 antigen (150 kDa TGF-beta-1-binding protein) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7) (Platelet-specific Gov antigen) (p180) (r150) (CD antigen CD109) Homo sapiens (Human) hair follicle development [GO:0001942]; keratinocyte proliferation [GO:0043616]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of peptidase activity [GO:0010466]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of stem cell proliferation [GO:2000647]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of wound healing [GO:0061045]; osteoclast fusion [GO:0072675]; protein phosphorylation [GO:0006468]; regulation of keratinocyte differentiation [GO:0045616]; stem cell proliferation [GO:0072089] GO:0001933; GO:0001942; GO:0004867; GO:0005576; GO:0005615; GO:0005829; GO:0005886; GO:0006468; GO:0009986; GO:0010466; GO:0010839; GO:0030512; GO:0031092; GO:0043616; GO:0045616; GO:0050431; GO:0061045; GO:0072089; GO:0072675; GO:2000647 27063 XR_003826048.2 2124 3234 936 2077 2366 NA NA NA NA NA NA 27064 XR_006395512.1 119 89 43 176 37 NA NA NA NA NA NA 27065 XM_044307253.1 69 65 2 79 10 NA NA NA NA NA NA 27066 XM_044316818.1 242 427 337 340 245 NA NA NA NA NA NA 27067 XM_044308451.1 473 276 103 254 157 NA NA NA NA NA NA 27068 XM_029342190.2 956 310 673 637 435 Q5VTB9 7.74e-58 E3 ubiquitin-protein ligase RNF220 (EC 2.3.2.27) (RING finger protein 220) (RING-type E3 ubiquitin transferase RNF220) Homo sapiens (Human) dorsal/ventral neural tube patterning [GO:0021904]; noradrenergic neuron development [GO:0003358]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; protein autoubiquitination [GO:0051865]; protein monoubiquitination [GO:0006513]; protein ubiquitination [GO:0016567]; regulation of transcription regulatory region DNA binding [GO:2000677] GO:0003358; GO:0004842; GO:0005634; GO:0005652; GO:0005737; GO:0006513; GO:0008013; GO:0016567; GO:0021904; GO:0032991; GO:0046872; GO:0051091; GO:0051865; GO:0061630; GO:0090263; GO:2000677 27069 XM_044321450.1 1252 1350 1004 1041 1360 Q8WX92 2.03e-150 Negative elongation factor B (NELF-B) (Cofactor of BRCA1) Homo sapiens (Human) cell population proliferation [GO:0008283]; negative regulation of stem cell differentiation [GO:2000737]; negative regulation of transcription elongation by RNA polymerase II [GO:0034244]; stem cell differentiation [GO:0048863] GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0008283; GO:0032021; GO:0034244; GO:0048863; GO:2000737 27070 XM_029332863.2 415 221 145 508 413 P69525 5.27e-90 Transmembrane protease serine 9 (EC 3.4.21.-) (Polyserase-I) (Polyserine protease 1) (Polyserase-1) [Cleaved into: Serase-1; Serase-2; Serase-3] Mus musculus (Mouse) plasminogen activation [GO:0031639]; proteolysis [GO:0006508] GO:0004252; GO:0005886; GO:0006508; GO:0008236; GO:0031639 27071 XM_029332863.2 415 221 145 508 413 P69525 8.32e-76 Transmembrane protease serine 9 (EC 3.4.21.-) (Polyserase-I) (Polyserine protease 1) (Polyserase-1) [Cleaved into: Serase-1; Serase-2; Serase-3] Mus musculus (Mouse) plasminogen activation [GO:0031639]; proteolysis [GO:0006508] GO:0004252; GO:0005886; GO:0006508; GO:0008236; GO:0031639 27072 XM_029332863.2 415 221 145 508 413 P69525 1.43e-59 Transmembrane protease serine 9 (EC 3.4.21.-) (Polyserase-I) (Polyserine protease 1) (Polyserase-1) [Cleaved into: Serase-1; Serase-2; Serase-3] Mus musculus (Mouse) plasminogen activation [GO:0031639]; proteolysis [GO:0006508] GO:0004252; GO:0005886; GO:0006508; GO:0008236; GO:0031639 27073 XM_029332863.2 415 221 145 508 413 P69525 6.33e-58 Transmembrane protease serine 9 (EC 3.4.21.-) (Polyserase-I) (Polyserine protease 1) (Polyserase-1) [Cleaved into: Serase-1; Serase-2; Serase-3] Mus musculus (Mouse) plasminogen activation [GO:0031639]; proteolysis [GO:0006508] GO:0004252; GO:0005886; GO:0006508; GO:0008236; GO:0031639 27074 XM_029332863.2 415 221 145 508 413 P69525 3.04e-42 Transmembrane protease serine 9 (EC 3.4.21.-) (Polyserase-I) (Polyserine protease 1) (Polyserase-1) [Cleaved into: Serase-1; Serase-2; Serase-3] Mus musculus (Mouse) plasminogen activation [GO:0031639]; proteolysis [GO:0006508] GO:0004252; GO:0005886; GO:0006508; GO:0008236; GO:0031639 27075 XR_006392100.1 65 66 68 85 92 NA NA NA NA NA NA 27076 XM_044314874.1 3 0 1 0 21 B8VIU6 6.84e-64 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 27077 XR_006392786.1 0 0 16 0 23 NA NA NA NA NA NA 27078 XM_029353254.2 5 0 5 32 5 NA NA NA NA NA NA 27079 XR_003825751.2 18 1 4 12 35 NA NA NA NA NA NA 27080 XM_044328609.1 291 5 1273 185 249 NA NA NA NA NA NA 27081 XM_029346885.2 269 249 204 452 535 NA NA NA NA NA NA 27082 XM_044317222.1 98 352 223 414 150 O35231 9.73e-176 Kinesin-like protein KIFC3 Mus musculus (Mouse) epithelial cell-cell adhesion [GO:0090136]; Golgi organization [GO:0007030]; microtubule-based movement [GO:0007018]; microtubule-based process [GO:0007017]; zonula adherens maintenance [GO:0045218] GO:0005524; GO:0005794; GO:0005813; GO:0005871; GO:0005874; GO:0005915; GO:0007017; GO:0007018; GO:0007030; GO:0008017; GO:0008569; GO:0015630; GO:0030659; GO:0042802; GO:0045218; GO:0090136 27083 XM_044308022.1 2114 1659 982 1584 1008 Q8CID0 7.95e-143 Cysteine-rich protein 2-binding protein (CSRP2-binding protein) (ADA2A-containing complex subunit 2) (ATAC2) (CRP2-binding partner) (CRP2BP) (Lysine acetyltransferase 14) Mus musculus (Mouse) G2/M transition of mitotic cell cycle [GO:0000086]; histone acetylation [GO:0016573]; histone H3 acetylation [GO:0043966]; histone H3-K14 acetylation [GO:0044154]; regulation of cell cycle [GO:0051726]; regulation of cell division [GO:0051302]; regulation of DNA-templated transcription [GO:0006355]; regulation of embryonic development [GO:0045995]; regulation of histone deacetylation [GO:0031063]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tubulin deacetylation [GO:0090043] GO:0000086; GO:0004402; GO:0005634; GO:0005737; GO:0006355; GO:0006357; GO:0016573; GO:0031063; GO:0043966; GO:0044154; GO:0045995; GO:0051302; GO:0051726; GO:0072686; GO:0090043; GO:0140672 27084 XM_044327498.1 0 0 27 0 0 Q9R1A8 0 E3 ubiquitin-protein ligase COP1 (EC 2.3.2.27) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1) (RING finger and WD repeat domain protein 2) (RING-type E3 ubiquitin transferase RFWD2) Mus musculus (Mouse) positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; response to ionizing radiation [GO:0010212] GO:0000139; GO:0010212; GO:0016607; GO:0031464; GO:0032436; GO:0043161; GO:0046872; GO:0061630 27085 XM_044325272.1 525 410 306 559 460 P00519 0 Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; actin filament polymerization [GO:0030041]; activated T cell proliferation [GO:0050798]; activation of protein kinase C activity [GO:1990051]; alpha-beta T cell differentiation [GO:0046632]; associative learning [GO:0008306]; autophagy [GO:0006914]; B cell proliferation involved in immune response [GO:0002322]; B cell receptor signaling pathway [GO:0050853]; B-1 B cell homeostasis [GO:0001922]; Bergmann glial cell differentiation [GO:0060020]; BMP signaling pathway [GO:0030509]; cardiac muscle cell proliferation [GO:0060038]; cell-cell adhesion [GO:0098609]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to dopamine [GO:1903351]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cellular senescence [GO:0090398]; cerebellum morphogenesis [GO:0021587]; DN4 thymocyte differentiation [GO:1904157]; DNA conformation change [GO:0071103]; endocytosis [GO:0006897]; endothelial cell migration [GO:0043542]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; integrin-mediated signaling pathway [GO:0007229]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; microspike assembly [GO:0030035]; mismatch repair [GO:0006298]; mitochondrial depolarization [GO:0051882]; mitotic cell cycle [GO:0000278]; myoblast proliferation [GO:0051450]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cellular senescence [GO:2000773]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phospholipase C activity [GO:1900275]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; neural tube closure [GO:0001843]; neuroepithelial cell differentiation [GO:0060563]; neuromuscular process controlling balance [GO:0050885]; neuron death [GO:0070997]; neuron differentiation [GO:0030182]; neuropilin signaling pathway [GO:0038189]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; podocyte apoptotic process [GO:1903210]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament binding [GO:1904531]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel branching [GO:1905555]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of dendrite development [GO:1900006]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of extracellular matrix organization [GO:1903055]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of hydrogen peroxide-mediated programmed cell death [GO:1901300]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of microtubule binding [GO:1904528]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of T cell migration [GO:2000406]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type II interferon production [GO:0032729]; positive regulation of vasoconstriction [GO:0045907]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein localization to cytoplasmic microtubule plus-end [GO:1904518]; protein modification process [GO:0036211]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of apoptotic process [GO:0042981]; regulation of autophagy [GO:0010506]; regulation of axon extension [GO:0030516]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of cell adhesion [GO:0030155]; regulation of cell cycle [GO:0051726]; regulation of cell motility [GO:2000145]; regulation of DNA-templated transcription [GO:0006355]; regulation of endocytosis [GO:0030100]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of microtubule polymerization [GO:0031113]; regulation of modification of synaptic structure [GO:1905244]; regulation of response to DNA damage stimulus [GO:2001020]; regulation of T cell differentiation [GO:0045580]; response to endoplasmic reticulum stress [GO:0034976]; response to epinephrine [GO:0071871]; response to oxidative stress [GO:0006979]; response to xenobiotic stimulus [GO:0009410]; signal transduction in response to DNA damage [GO:0042770]; spleen development [GO:0048536]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; transitional one stage B cell differentiation [GO:0002333] GO:0000278; GO:0000287; GO:0000400; GO:0000405; GO:0001726; GO:0001784; GO:0001843; GO:0001922; GO:0001934; GO:0002322; GO:0002333; GO:0003677; GO:0003713; GO:0003785; GO:0004515; GO:0004672; GO:0004713; GO:0004715; GO:0005080; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005739; GO:0005783; GO:0005829; GO:0006298; GO:0006355; GO:0006468; GO:0006897; GO:0006914; GO:0006974; GO:0006979; GO:0007173; GO:0007204; GO:0007229; GO:0007249; GO:0008022; GO:0008306; GO:0008630; GO:0009410; GO:0009791; GO:0010506; GO:0010595; GO:0015629; GO:0016301; GO:0016604; GO:0017124; GO:0018108; GO:0019905; GO:0021587; GO:0022408; GO:0030035; GO:0030036; GO:0030041; GO:0030100; GO:0030145; GO:0030155; GO:0030182; GO:0030425; GO:0030426; GO:0030509; GO:0030514; GO:0030516; GO:0031113; GO:0031965; GO:0032489; GO:0032729; GO:0032743; GO:0032956; GO:0032991; GO:0033690; GO:0034446; GO:0034599; GO:0034976; GO:0035791; GO:0036211; GO:0038083; GO:0038096; GO:0038189; GO:0038191; GO:0042169; GO:0042770; GO:0042981; GO:0043025; GO:0043065; GO:0043123; GO:0043124; GO:0043525; GO:0043542; GO:0043621; GO:0045580; GO:0045907; GO:0045930; GO:0045931; GO:0045944; GO:0046632; GO:0046777; GO:0046875; GO:0048146; GO:0048471; GO:0048536; GO:0048538; GO:0050731; GO:0050798; GO:0050852; GO:0050853; GO:0050885; GO:0051015; GO:0051019; GO:0051281; GO:0051353; GO:0051444; GO:0051450; GO:0051496; GO:0051649; GO:0051726; GO:0051882; GO:0051894; GO:0060020; GO:0060038; GO:0060563; GO:0070064; GO:0070097; GO:0070301; GO:0070371; GO:0070373; GO:0070374; GO:0070997; GO:0071103; GO:0071222; GO:0071560; GO:0071871; GO:0071901; GO:0090050; GO:0090398; GO:0098609; GO:0098794; GO:1900006; GO:1900026; GO:1900272; GO:1900275; GO:1901300; GO:1902036; GO:1903055; GO:1903210; GO:1903351; GO:1903905; GO:1904157; GO:1904518; GO:1904528; GO:1904531; GO:1905244; GO:1905555; GO:1990051; GO:1990837; GO:2000096; GO:2000145; GO:2000249; GO:2000251; GO:2000352; GO:2000406; GO:2000773; GO:2001020 27086 XM_029348461.2 13 71 10 119 9 Q9Y573 3.26e-32 Actin-binding protein IPP (Intracisternal A particle-promoted polypeptide) (IPP) (Kelch-like protein 27) Homo sapiens (Human) NA GO:0003779; GO:0005737; GO:0015629 27087 XM_029336085.2 103 91 30 93 63 Q9SR22 8.04e-67 Pectin acetylesterase 5 (EC 3.1.1.-) Arabidopsis thaliana (Mouse-ear cress) cell wall organization [GO:0071555] GO:0005576; GO:0009505; GO:0052793; GO:0071555 27088 XM_029338776.2 19 22 7 13 54 NA NA NA NA NA NA 27089 XR_003825499.2 423 217 198 361 241 NA NA NA NA NA NA 27090 XM_029356398.2 325 197 202 715 971 Q6ZR37 2.42e-84 Pleckstrin homology domain-containing family G member 7 (PH domain-containing family G member 7) Homo sapiens (Human) Rho protein signal transduction [GO:0007266] GO:0005085; GO:0007266 27091 XM_029357547.2 0 0 0 5 58 NA NA NA NA NA NA 27092 XM_044322265.1 2589 926 1207 5270 7112 B3EWZ3 2.7e-70 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 27093 XM_044322265.1 2589 926 1207 5270 7112 B3EWZ3 2.9e-67 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 27094 XM_044322265.1 2589 926 1207 5270 7112 B3EWZ3 2.16e-66 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 27095 XM_044322265.1 2589 926 1207 5270 7112 B3EWZ3 7.23e-65 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 27096 XM_044322265.1 2589 926 1207 5270 7112 B3EWZ3 2.9e-64 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 27097 XM_044322265.1 2589 926 1207 5270 7112 B3EWZ3 3.49e-64 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 27098 XM_044322265.1 2589 926 1207 5270 7112 B3EWZ3 3.27e-63 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 27099 XM_044322265.1 2589 926 1207 5270 7112 B3EWZ3 1.23e-62 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 27100 XM_044322265.1 2589 926 1207 5270 7112 B3EWZ3 1.41e-62 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 27101 XM_044322265.1 2589 926 1207 5270 7112 B3EWZ3 2.85e-62 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 27102 XM_044322265.1 2589 926 1207 5270 7112 B3EWZ3 2.53e-61 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 27103 XM_044322265.1 2589 926 1207 5270 7112 B3EWZ3 3.07e-61 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 27104 XM_044322265.1 2589 926 1207 5270 7112 B3EWZ3 4.57e-61 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 27105 XM_044322265.1 2589 926 1207 5270 7112 B3EWZ3 2.7e-60 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 27106 XM_044322265.1 2589 926 1207 5270 7112 B3EWZ3 3.09e-60 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 27107 XM_044322265.1 2589 926 1207 5270 7112 B3EWZ3 1.25e-58 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 27108 XM_044322265.1 2589 926 1207 5270 7112 B3EWZ3 2.73e-58 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 27109 XM_044322265.1 2589 926 1207 5270 7112 B3EWZ3 4.82e-57 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 27110 XM_044322265.1 2589 926 1207 5270 7112 B3EWZ3 2.48e-56 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 27111 XM_044322265.1 2589 926 1207 5270 7112 B3EWZ3 6.38e-56 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 27112 XM_044322265.1 2589 926 1207 5270 7112 B3EWZ3 1.8e-55 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 27113 XM_044322265.1 2589 926 1207 5270 7112 B3EWZ3 1.3e-53 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 27114 XM_044322265.1 2589 926 1207 5270 7112 B3EWZ3 8.99e-53 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 27115 XM_044322265.1 2589 926 1207 5270 7112 B3EWZ3 3.74e-50 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 27116 XM_044322265.1 2589 926 1207 5270 7112 B3EWZ3 1.37e-49 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 27117 XM_044322265.1 2589 926 1207 5270 7112 B3EWZ3 5.97e-48 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 27118 XM_044322265.1 2589 926 1207 5270 7112 B3EWZ3 5.51e-46 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 27119 XM_044322265.1 2589 926 1207 5270 7112 B3EWZ3 1.14e-45 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 27120 XM_044322265.1 2589 926 1207 5270 7112 B3EWZ3 2.09e-43 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 27121 XM_044322265.1 2589 926 1207 5270 7112 B3EWZ3 2.83e-43 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 27122 XM_044322265.1 2589 926 1207 5270 7112 B3EWZ3 9.85e-40 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 27123 XM_044322265.1 2589 926 1207 5270 7112 B3EWZ3 1.75e-38 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 27124 XM_044322265.1 2589 926 1207 5270 7112 B3EWZ3 1.56e-37 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 27125 XM_044322265.1 2589 926 1207 5270 7112 B3EWZ3 2.7e-24 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 27126 XM_044326243.1 12 41 15 87 59 NA NA NA NA NA NA 27127 XM_044319615.1 53 10 9 49 73 NA NA NA NA NA NA 27128 XM_044318840.1 30 0 12 0 0 A0A1L8F5J9 6.75e-53 Glutamate receptor ionotropic, NMDA 1 (GluN1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1) Xenopus laevis (African clawed frog) response to zinc ion [GO:0010043] GO:0004972; GO:0005886; GO:0010043; GO:0017146; GO:0045211; GO:0046872 27129 XM_044312506.1 198 34 136 119 675 P10394 1.06e-23 Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 27130 XM_044308303.1 71 84 11 34 0 Q570Y9 1.08e-42 DEP domain-containing mTOR-interacting protein (DEP domain-containing protein 6) Mus musculus (Mouse) intracellular signal transduction [GO:0035556]; negative regulation of cell size [GO:0045792]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of TOR signaling [GO:0032007]; negative regulation of TORC1 signaling [GO:1904262]; negative regulation of TORC2 signaling [GO:1903940]; regulation of extrinsic apoptotic signaling pathway [GO:2001236] GO:0006469; GO:0032007; GO:0035556; GO:0045792; GO:1903940; GO:1904262; GO:2001236 27131 XM_029349897.2 258 105 121 162 159 P07992 3.47e-92 DNA excision repair protein ERCC-1 Homo sapiens (Human) cell population proliferation [GO:0008283]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; embryonic organ development [GO:0048568]; interstrand cross-link repair [GO:0036297]; isotype switching [GO:0045190]; male gonad development [GO:0008584]; meiotic mismatch repair [GO:0000710]; mitotic recombination [GO:0006312]; multicellular organism aging [GO:0010259]; multicellular organism growth [GO:0035264]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of telomere maintenance [GO:0032205]; nucleotide-excision repair [GO:0006289]; oogenesis [GO:0048477]; positive regulation of t-circle formation [GO:1904431]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; post-embryonic hemopoiesis [GO:0035166]; pyrimidine dimer repair by nucleotide-excision repair [GO:0000720]; replicative senescence [GO:0090399]; response to cadmium ion [GO:0046686]; response to immobilization stress [GO:0035902]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to sucrose [GO:0009744]; response to X-ray [GO:0010165]; spermatogenesis [GO:0007283]; syncytium formation [GO:0006949]; t-circle formation [GO:0090656]; telomeric DNA-containing double minutes formation [GO:0061819]; UV protection [GO:0009650]; UV-damage excision repair [GO:0070914] GO:0000109; GO:0000110; GO:0000710; GO:0000720; GO:0000781; GO:0001094; GO:0003684; GO:0003697; GO:0005654; GO:0005737; GO:0006281; GO:0006289; GO:0006303; GO:0006312; GO:0006949; GO:0006979; GO:0007283; GO:0007584; GO:0008022; GO:0008283; GO:0008584; GO:0009650; GO:0009744; GO:0010165; GO:0010259; GO:0019904; GO:0032205; GO:0035166; GO:0035264; GO:0035902; GO:0036297; GO:0045190; GO:0046686; GO:0048477; GO:0048568; GO:0060261; GO:0061819; GO:0070522; GO:0070914; GO:0090399; GO:0090656; GO:1904431; GO:1905765; GO:1990841 27132 XR_006391781.1 28 13 27 21 34 NA NA NA NA NA NA 27133 XM_029350353.2 18 16 40 7 5 NA NA NA NA NA NA 27134 XM_029335543.2 219 1 1 624 1 NA NA NA NA NA NA 27135 XM_029355618.2 789 477 275 153 206 NA NA NA NA NA NA 27136 XM_029338336.2 79 282 73 199 76 NA NA NA NA NA NA 27137 XM_044324204.1 0 10 0 0 0 Q8C206 3.95e-26 G-protein coupled receptor 157 Mus musculus (Mouse) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; circadian behavior [GO:0048512]; G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; radial glial cell differentiation [GO:0060019] GO:0004930; GO:0005886; GO:0007166; GO:0007186; GO:0007189; GO:0048512; GO:0051482; GO:0060019; GO:0060170 27138 XM_029341539.2 0 0 0 39 0 P05363 7.73e-33 Substance-K receptor (SKR) (NK-2 receptor) (NK-2R) (Neurokinin A receptor) (Tachykinin receptor 2) Bos taurus (Bovine) positive regulation of flagellated sperm motility [GO:1902093]; regulation of uterine smooth muscle contraction [GO:0070472] GO:0004995; GO:0005886; GO:0016497; GO:0061827; GO:0070472; GO:0097225; GO:1902093 27139 XM_029356923.2 124 117 58 61 128 NA NA NA NA NA NA 27140 XM_044322274.1 1 0 0 6 12 Q6AZB8 6.73e-28 Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0004518; GO:0005634; GO:0005737; GO:0046872 27141 XM_044327033.1 110 35 0 145 84 Q6P6B7 4.03e-93 Ankyrin repeat domain-containing protein 16 Homo sapiens (Human) tRNA modification [GO:0006400] GO:0005634; GO:0005737; GO:0006400 27142 XM_029327522.2 311 292 265 283 6 NA NA NA NA NA NA 27143 XM_029330737.2 4491 4744 3016 4366 4707 NA NA NA NA NA NA 27144 XM_029336274.2 13 0 0 0 23 NA NA NA NA NA NA 27145 XR_006394683.1 0 0 0 44 0 NA NA NA NA NA NA 27146 XM_029325789.2 118 118 162 134 119 Q5PPN7 7.88e-45 Mitochondrial potassium channel (MITOK) (Coiled-coil domain-containing protein 51) Rattus norvegicus (Rat) cell volume homeostasis [GO:0006884]; mitochondrial potassium ion transmembrane transport [GO:0140141]; potassium ion transmembrane transport [GO:0071805] GO:0005743; GO:0006884; GO:0034705; GO:0062156; GO:0062157; GO:0071805; GO:0140141 27147 XM_029357932.2 0 0 3 6 5 NA NA NA NA NA NA 27148 XM_029328912.2 113 57 19 102 119 P24045 6.18e-61 Gamma-aminobutyric acid receptor subunit beta-4 (GABA(A) receptor subunit beta-4) Gallus gallus (Chicken) chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165] GO:0004890; GO:0005231; GO:0005254; GO:0005886; GO:0007165; GO:0007268; GO:0030594; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:1902476; GO:1902711; GO:1904315 27149 XM_029343471.2 52 41 23 48 89 NA NA NA NA NA NA 27150 XM_044318878.1 118 214 90 277 156 NA NA NA NA NA NA 27151 XM_029325660.2 0 22 88 190 136 Q9VCA2 7.44e-65 Organic cation transporter protein Drosophila melanogaster (Fruit fly) apoptotic process [GO:0006915]; ion transport [GO:0006811] GO:0006811; GO:0006915; GO:0016020; GO:0022857 27152 XM_029336048.2 447 214 234 256 347 Q6INI5 8.44e-37 Nucleolar protein 11 Xenopus laevis (African clawed frog) maturation of SSU-rRNA [GO:0030490]; positive regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901838] GO:0005730; GO:0030490; GO:1901838 27153 XM_044306845.1 13 17 14 27 81 NA NA NA NA NA NA 27154 XM_044323470.1 539 663 418 1421 712 P0C1Q2 0 Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (EC 3.1.4.35) (EC 3.1.4.53) (cAMP and cGMP phosphodiesterase 11A) Mus musculus (Mouse) metabolic process [GO:0008152]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; signal transduction [GO:0007165] GO:0004112; GO:0004114; GO:0004115; GO:0004118; GO:0005829; GO:0007165; GO:0008152; GO:0010754; GO:0030553; GO:0043204; GO:0043951; GO:0046872; GO:0047555 27155 XM_029334197.2 87 63 14 69 8 P25931 6.57e-34 RYamide receptor (Neuropeptide Y-like receptor) (NPY-R) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218] GO:0001653; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0016020 27156 XR_006396016.1 108 33 38 90 95 NA NA NA NA NA NA 27157 XM_044322331.1 0 0 2 7 0 NA NA NA NA NA NA 27158 XM_029332177.2 802 594 474 272 242 Q7YRB7 1.12e-179 Amine oxidase [flavin-containing] B (EC 1.4.3.21) (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B) Canis lupus familiaris (Dog) (Canis familiaris) NA GO:0005739; GO:0005741; GO:0008131; GO:0052595; GO:0052596; GO:0097621 27159 XM_044312616.1 1 2 2 0 15 NA NA NA NA NA NA 27160 XM_029335903.2 16 0 13 0 0 Q9CYI0 1.48e-24 Protein Njmu-R1 Mus musculus (Mouse) intracellular protein transport [GO:0006886]; vesicle tethering to Golgi [GO:0099041] GO:0005802; GO:0006886; GO:0031410; GO:0099041 27161 XM_029335903.2 16 0 13 0 0 Q9CYI0 1.48e-24 Protein Njmu-R1 Mus musculus (Mouse) intracellular protein transport [GO:0006886]; vesicle tethering to Golgi [GO:0099041] GO:0005802; GO:0006886; GO:0031410; GO:0099041 27162 XM_044320525.1 78 320 198 40 39 NA NA NA NA NA NA 27163 XM_029343744.2 8 13 0 17 95 NA NA NA NA NA NA 27164 XM_044324213.1 583 582 222 454 321 NA NA NA NA NA NA 27165 XM_044309752.1 115 249 165 97 354 P10079 0 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 27166 XM_044309752.1 115 249 165 97 354 P10079 0 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 27167 XM_044309752.1 115 249 165 97 354 P10079 0 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 27168 XM_044309752.1 115 249 165 97 354 P10079 0 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 27169 XM_044309752.1 115 249 165 97 354 P10079 0 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 27170 XM_029329318.2 136 0 114 81 89 NA NA NA NA NA NA 27171 XM_029357059.2 2999 2026 1727 3119 3144 O55098 9e-126 Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase) Mus musculus (Mouse) cell cycle [GO:0007049]; lymphocyte aggregation [GO:0071593]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of lymphocyte migration [GO:2000401] GO:0004674; GO:0005524; GO:0005737; GO:0005886; GO:0006468; GO:0007049; GO:0042802; GO:0042803; GO:0046777; GO:0071593; GO:0106310; GO:2000401 27172 XM_029357059.2 2999 2026 1727 3119 3144 O55098 1.34e-63 Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase) Mus musculus (Mouse) cell cycle [GO:0007049]; lymphocyte aggregation [GO:0071593]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of lymphocyte migration [GO:2000401] GO:0004674; GO:0005524; GO:0005737; GO:0005886; GO:0006468; GO:0007049; GO:0042802; GO:0042803; GO:0046777; GO:0071593; GO:0106310; GO:2000401 27173 XM_029341817.2 58 41 22 367 355 NA NA NA NA NA NA 27174 XM_044314852.1 33 20 0 35 0 E1BY51 2.59e-46 Transmembrane protein 17 Gallus gallus (Chicken) cilium assembly [GO:0060271]; non-motile cilium assembly [GO:1905515]; smoothened signaling pathway [GO:0007224] GO:0007224; GO:0035869; GO:0036038; GO:0060170; GO:0060271; GO:1905515 27175 XM_029342952.2 0 5 0 14 0 NA NA NA NA NA NA 27176 XM_044319736.1 0 0 16 19 0 NA NA NA NA NA NA 27177 XM_044310363.1 30 27 13 25 38 Q15485 2.53e-79 Ficolin-2 (37 kDa elastin-binding protein) (Collagen/fibrinogen domain-containing protein 2) (EBP-37) (Ficolin-B) (Ficolin-beta) (Hucolin) (L-ficolin) (Serum lectin p35) Homo sapiens (Human) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; positive regulation of opsonization [GO:1903028]; proteolysis [GO:0006508]; recognition of apoptotic cell [GO:0043654] GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005576; GO:0005581; GO:0005615; GO:0006508; GO:0008228; GO:0009897; GO:0042802; GO:0043394; GO:0043654; GO:0046872; GO:0048306; GO:0050829; GO:0050830; GO:0062023; GO:0070062; GO:0072562; GO:0097367; GO:1903028; GO:1905370; GO:2001065 27178 XM_029337847.2 51 162 0 0 188 NA NA NA NA NA NA 27179 XM_044311868.1 15 0 1 0 18 NA NA NA NA NA NA 27180 XM_044316328.1 1133 483 304 971 544 Q92485 2.55e-131 Acid sphingomyelinase-like phosphodiesterase 3b (ASM-like phosphodiesterase 3b) (EC 3.1.4.-) Homo sapiens (Human) inflammatory response [GO:0006954]; innate immune response [GO:0045087]; membrane lipid catabolic process [GO:0046466]; negative regulation of inflammatory response [GO:0050728]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; sphingomyelin catabolic process [GO:0006685] GO:0004767; GO:0005615; GO:0005886; GO:0006685; GO:0006954; GO:0008081; GO:0008270; GO:0016798; GO:0034122; GO:0045087; GO:0046466; GO:0050728; GO:0070062 27181 XM_029337369.2 21 0 39 42 22 NA NA NA NA NA NA 27182 XM_029341974.2 431 118 70 28 0 Q8N5H7 3.12e-29 SH2 domain-containing protein 3C (Cas/HEF1-associated signal transducer) (Chat-H) (Novel SH2-containing protein 3) (SH2 domain-containing Eph receptor-binding protein 1) (SHEP1) Homo sapiens (Human) JNK cascade [GO:0007254]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; small GTPase mediated signal transduction [GO:0007264] GO:0001784; GO:0005085; GO:0005829; GO:0007254; GO:0007264; GO:0030424; GO:0032587; GO:0033138 27183 XM_029351217.2 0 8 13 7 1 NA NA NA NA NA NA 27184 XM_044319564.1 73 34 0 47 33 NA NA NA NA NA NA 27185 XM_029357029.2 11980 10803 6724 11813 10754 P81004 4.19e-131 Voltage-dependent anion-selective channel protein 2 (VDAC-2) (Outer mitochondrial membrane protein porin) Xenopus laevis (African clawed frog) NA GO:0000166; GO:0005741; GO:0008308; GO:0015288; GO:0046930 27186 XM_029334397.2 1756 1511 883 1660 1729 C1C4R8 5.9e-104 Dehydrogenase/reductase SDR family member 6 (EC 1.1.1.-) ((R)-beta-hydroxybutyrate dehydrogenase) (3-hydroxybutyrate dehydrogenase type 2) (EC 1.1.1.30) (4-oxo-L-proline reductase) (EC 1.1.1.104) (Oxidoreductase UCPA) (Short chain dehydrogenase/reductase family 15C member 1) Lithobates catesbeianus (American bullfrog) (Rana catesbeiana) heme metabolic process [GO:0042168]; iron ion homeostasis [GO:0055072]; lipid metabolic process [GO:0006629]; siderophore biosynthetic process [GO:0019290] GO:0003858; GO:0005737; GO:0006629; GO:0016617; GO:0016628; GO:0019290; GO:0042168; GO:0055072 27187 XM_044306960.1 988 993 624 1048 1165 Q8R0H9 3.26e-88 ADP-ribosylation factor-binding protein GGA1 (Gamma-adaptin-related protein 1) (Golgi-localized, gamma ear-containing, ARF-binding protein 1) Mus musculus (Mouse) Golgi to plasma membrane protein transport [GO:0043001]; Golgi to plasma membrane transport [GO:0006893]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein catabolic process [GO:0030163]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998] GO:0005654; GO:0005769; GO:0005794; GO:0005802; GO:0005829; GO:0006886; GO:0006893; GO:0008104; GO:0030163; GO:0031267; GO:0031901; GO:0032991; GO:0034394; GO:0035091; GO:0042147; GO:0043001; GO:0043130; GO:0043231; GO:0045732; GO:1901998; GO:1903441 27188 XM_044306960.1 988 993 624 1048 1165 Q8R0H9 8.01e-33 ADP-ribosylation factor-binding protein GGA1 (Gamma-adaptin-related protein 1) (Golgi-localized, gamma ear-containing, ARF-binding protein 1) Mus musculus (Mouse) Golgi to plasma membrane protein transport [GO:0043001]; Golgi to plasma membrane transport [GO:0006893]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein catabolic process [GO:0030163]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998] GO:0005654; GO:0005769; GO:0005794; GO:0005802; GO:0005829; GO:0006886; GO:0006893; GO:0008104; GO:0030163; GO:0031267; GO:0031901; GO:0032991; GO:0034394; GO:0035091; GO:0042147; GO:0043001; GO:0043130; GO:0043231; GO:0045732; GO:1901998; GO:1903441 27189 XM_029349794.2 470 405 325 235 280 Q4R516 5.8e-30 Elongation of very long chain fatty acids protein 5 (EC 2.3.1.199) (3-keto acyl-CoA synthase ELOVL5) (ELOVL fatty acid elongase 5) (ELOVL FA elongase 5) (Very long chain 3-ketoacyl-CoA synthase 5) (Very long chain 3-oxoacyl-CoA synthase 5) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) fatty acid elongation, monounsaturated fatty acid [GO:0034625]; fatty acid elongation, polyunsaturated fatty acid [GO:0034626]; fatty acid elongation, saturated fatty acid [GO:0019367]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; unsaturated fatty acid biosynthetic process [GO:0006636]; very long-chain fatty acid biosynthetic process [GO:0042761] GO:0005789; GO:0006636; GO:0009922; GO:0019367; GO:0030425; GO:0034625; GO:0034626; GO:0035338; GO:0042761; GO:0043025; GO:0097447; GO:0102756 27190 XM_029329778.2 3314 1827 1152 3728 2332 P79134 1.02e-72 Annexin A6 (Annexin VI) (Annexin-6) Bos taurus (Bovine) apoptotic signaling pathway [GO:0097190]; biomineral tissue development [GO:0031214]; calcium ion import [GO:0070509]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; growth plate cartilage chondrocyte differentiation [GO:0003418]; mitochondrial calcium ion homeostasis [GO:0051560]; negative regulation of sequestering of calcium ion [GO:0051283]; neural crest cell migration [GO:0001755]; plasma membrane repair [GO:0001778]; regulation of muscle contraction [GO:0006937] GO:0001725; GO:0001755; GO:0001778; GO:0001786; GO:0003418; GO:0005262; GO:0005509; GO:0005525; GO:0005544; GO:0005737; GO:0005886; GO:0005925; GO:0006816; GO:0006937; GO:0008201; GO:0015276; GO:0015485; GO:0016020; GO:0019899; GO:0030061; GO:0031214; GO:0031982; GO:0035374; GO:0038024; GO:0042470; GO:0042584; GO:0048306; GO:0048471; GO:0051015; GO:0051283; GO:0051560; GO:0070509; GO:0070588; GO:0097190 27191 XM_029329778.2 3314 1827 1152 3728 2332 P79134 2.3e-59 Annexin A6 (Annexin VI) (Annexin-6) Bos taurus (Bovine) apoptotic signaling pathway [GO:0097190]; biomineral tissue development [GO:0031214]; calcium ion import [GO:0070509]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; growth plate cartilage chondrocyte differentiation [GO:0003418]; mitochondrial calcium ion homeostasis [GO:0051560]; negative regulation of sequestering of calcium ion [GO:0051283]; neural crest cell migration [GO:0001755]; plasma membrane repair [GO:0001778]; regulation of muscle contraction [GO:0006937] GO:0001725; GO:0001755; GO:0001778; GO:0001786; GO:0003418; GO:0005262; GO:0005509; GO:0005525; GO:0005544; GO:0005737; GO:0005886; GO:0005925; GO:0006816; GO:0006937; GO:0008201; GO:0015276; GO:0015485; GO:0016020; GO:0019899; GO:0030061; GO:0031214; GO:0031982; GO:0035374; GO:0038024; GO:0042470; GO:0042584; GO:0048306; GO:0048471; GO:0051015; GO:0051283; GO:0051560; GO:0070509; GO:0070588; GO:0097190 27192 XM_029329778.2 3314 1827 1152 3728 2332 P79134 3.02e-38 Annexin A6 (Annexin VI) (Annexin-6) Bos taurus (Bovine) apoptotic signaling pathway [GO:0097190]; biomineral tissue development [GO:0031214]; calcium ion import [GO:0070509]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; growth plate cartilage chondrocyte differentiation [GO:0003418]; mitochondrial calcium ion homeostasis [GO:0051560]; negative regulation of sequestering of calcium ion [GO:0051283]; neural crest cell migration [GO:0001755]; plasma membrane repair [GO:0001778]; regulation of muscle contraction [GO:0006937] GO:0001725; GO:0001755; GO:0001778; GO:0001786; GO:0003418; GO:0005262; GO:0005509; GO:0005525; GO:0005544; GO:0005737; GO:0005886; GO:0005925; GO:0006816; GO:0006937; GO:0008201; GO:0015276; GO:0015485; GO:0016020; GO:0019899; GO:0030061; GO:0031214; GO:0031982; GO:0035374; GO:0038024; GO:0042470; GO:0042584; GO:0048306; GO:0048471; GO:0051015; GO:0051283; GO:0051560; GO:0070509; GO:0070588; GO:0097190 27193 XM_029329778.2 3314 1827 1152 3728 2332 P79134 1.77e-34 Annexin A6 (Annexin VI) (Annexin-6) Bos taurus (Bovine) apoptotic signaling pathway [GO:0097190]; biomineral tissue development [GO:0031214]; calcium ion import [GO:0070509]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; growth plate cartilage chondrocyte differentiation [GO:0003418]; mitochondrial calcium ion homeostasis [GO:0051560]; negative regulation of sequestering of calcium ion [GO:0051283]; neural crest cell migration [GO:0001755]; plasma membrane repair [GO:0001778]; regulation of muscle contraction [GO:0006937] GO:0001725; GO:0001755; GO:0001778; GO:0001786; GO:0003418; GO:0005262; GO:0005509; GO:0005525; GO:0005544; GO:0005737; GO:0005886; GO:0005925; GO:0006816; GO:0006937; GO:0008201; GO:0015276; GO:0015485; GO:0016020; GO:0019899; GO:0030061; GO:0031214; GO:0031982; GO:0035374; GO:0038024; GO:0042470; GO:0042584; GO:0048306; GO:0048471; GO:0051015; GO:0051283; GO:0051560; GO:0070509; GO:0070588; GO:0097190 27194 XR_006395759.1 99 15 92 26 140 NA NA NA NA NA NA 27195 XR_006395494.1 0 9 10 6 20 NA NA NA NA NA NA 27196 XM_044324421.1 31 14 43 76 152 P10079 0 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 27197 XM_044324421.1 31 14 43 76 152 P10079 0 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 27198 XM_044324421.1 31 14 43 76 152 P10079 0 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 27199 XM_044324421.1 31 14 43 76 152 P10079 0 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 27200 XM_044324421.1 31 14 43 76 152 P10079 4.29e-98 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 27201 XM_029357446.2 2394 2862 2153 2894 2438 Q6VTH5 4.82e-70 Radial spoke head 1 homolog (Meichroacidin homolog) (Meichroacidin-like sperm-specific axonemal protein) (Testis-specific gene A2-like protein) Cyprinus carpio (Common carp) cell differentiation [GO:0030154]; meiotic cell cycle [GO:0051321]; spermatogenesis [GO:0007283] GO:0005737; GO:0005856; GO:0007283; GO:0030154; GO:0031514; GO:0051321 27202 XM_044317663.1 1271 650 106 125 600 NA NA NA NA NA NA 27203 XM_029337017.2 1024 220 0 282 739 NA NA NA NA NA NA 27204 XR_006394634.1 0 0 0 15 6 NA NA NA NA NA NA 27205 XM_029347524.2 670 617 364 627 575 P49915 0 GMP synthase [glutamine-hydrolyzing] (EC 6.3.5.2) (GMP synthetase) (Glutamine amidotransferase) Homo sapiens (Human) glutamine metabolic process [GO:0006541]; GMP biosynthetic process [GO:0006177]; purine nucleobase biosynthetic process [GO:0009113]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168] GO:0003921; GO:0003922; GO:0005524; GO:0005829; GO:0006177; GO:0006541; GO:0009113; GO:0009168 27206 XM_044327426.1 0 0 7 36 31 O70165 6.49e-67 Ficolin-1 (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin-alpha) (M-ficolin) Mus musculus (Mouse) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation, lectin pathway [GO:0001867]; G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of interleukin-8 production [GO:0032757] GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005581; GO:0005615; GO:0007186; GO:0030246; GO:0031232; GO:0032757; GO:0038187; GO:0046872; GO:0062023; GO:0097367 27207 XR_006391338.1 254 157 207 161 291 NA NA NA NA NA NA 27208 XR_006395673.1 1544 2407 1294 3808 1842 NA NA NA NA NA NA 27209 XM_029356361.2 991 469 513 1288 259 P26630 1.52e-90 Paired box protein Pax-6 (Pax[Zf-a]) Danio rerio (Zebrafish) (Brachydanio rerio) anatomical structure development [GO:0048856]; anterior/posterior pattern specification [GO:0009952]; epithalamus development [GO:0021538]; forebrain development [GO:0030900]; habenula development [GO:0021986]; hindbrain development [GO:0030902]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression [GO:0010468]; regulation of transcription by RNA polymerase II [GO:0006357]; retinal cone cell differentiation [GO:0042670]; retinal rod cell differentiation [GO:0060221] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0008284; GO:0009952; GO:0010468; GO:0021538; GO:0021986; GO:0030900; GO:0030902; GO:0042670; GO:0043565; GO:0045944; GO:0048856; GO:0060221 27210 XM_044310257.1 0 3 0 0 9 NA NA NA NA NA NA 27211 XM_044308337.1 48 84 58 168 208 NA NA NA NA NA NA 27212 XM_044326959.1 7845 17533 8096 4845 7731 NA NA NA NA NA NA 27213 XM_044322176.1 50 11 132 19 16 NA NA NA NA NA NA 27214 XM_029358313.2 0 0 0 0 24 Q9QYS2 0 Metabotropic glutamate receptor 3 (mGluR3) Mus musculus (Mouse) G protein-coupled glutamate receptor signaling pathway [GO:0007216]; gene expression [GO:0010467]; modulation of chemical synaptic transmission [GO:0050804]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; regulation of sensory perception of pain [GO:0051930]; regulation of synaptic transmission, glutamatergic [GO:0051966]; sensory perception of pain [GO:0019233]; synaptic transmission, glutamatergic [GO:0035249] GO:0001640; GO:0001641; GO:0005246; GO:0005886; GO:0007216; GO:0010467; GO:0014069; GO:0019233; GO:0030424; GO:0035249; GO:0042734; GO:0043005; GO:0043197; GO:0045211; GO:0048786; GO:0050804; GO:0051930; GO:0051966; GO:0097110; GO:0097449; GO:0098978; GO:0099170 27215 XM_044324803.1 326 257 240 371 463 Q9Y2G3 0 Phospholipid-transporting ATPase IF (EC 7.6.2.1) (ATPase IR) (ATPase class VI type 11B) (P4-ATPase flippase complex alpha subunit ATP11B) Homo sapiens (Human) aminophospholipid transport [GO:0015917]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; phospholipid translocation [GO:0045332] GO:0000287; GO:0005524; GO:0005637; GO:0005783; GO:0005802; GO:0005886; GO:0006811; GO:0015075; GO:0015917; GO:0016020; GO:0016887; GO:0031901; GO:0034220; GO:0035577; GO:0045332; GO:0055037; GO:0055038; GO:0090555; GO:0090556; GO:0140326; GO:1990531 27216 XM_029348256.2 21 49 30 46 58 NA NA NA NA NA NA 27217 XM_044320559.1 0 0 7 0 0 NA NA NA NA NA NA 27218 XM_044312095.1 0 75 0 0 5 Q99MW1 5.57e-30 Serine/threonine-protein kinase 31 (EC 2.7.11.1) Mus musculus (Mouse) protein phosphorylation [GO:0006468] GO:0001669; GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0006468; GO:0106310 27219 XM_029353958.2 2255 2385 1653 2127 1842 A7E3W5 3.98e-41 Synaptogyrin-2 (Cellugyrin) Bos taurus (Bovine) regulated exocytosis [GO:0045055]; synaptic vesicle membrane organization [GO:0048499] GO:0030672; GO:0031594; GO:0045055; GO:0048499 27220 XM_029335278.2 1557 539 774 1054 948 Q7ZXT3 2.67e-100 Enhancer of mRNA-decapping protein 4 Xenopus laevis (African clawed frog) deadenylation-independent decapping of nuclear-transcribed mRNA [GO:0031087] GO:0000932; GO:0005634; GO:0031087 27221 XM_029335278.2 1557 539 774 1054 948 Q7ZXT3 5.87e-63 Enhancer of mRNA-decapping protein 4 Xenopus laevis (African clawed frog) deadenylation-independent decapping of nuclear-transcribed mRNA [GO:0031087] GO:0000932; GO:0005634; GO:0031087 27222 XR_006396318.1 2 0 4 18 32 NA NA NA NA NA NA 27223 XM_044320185.1 837 664 527 806 1193 E9Q236 0 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 27224 XM_029347593.2 2206 1198 1230 579 926 NA NA NA NA NA NA 27225 XM_029355902.2 3457 3312 2204 2514 2189 A0A1W2P872 2.42e-49 RNA-binding protein Nova-2 Mus musculus (Mouse) central nervous system neuron development [GO:0021954]; mRNA processing [GO:0006397]; negative regulation of cold-induced thermogenesis [GO:0120163]; neuron differentiation [GO:0030182]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of axon guidance [GO:1902667]; regulation of RNA metabolic process [GO:0051252]; RNA splicing [GO:0008380] GO:0000381; GO:0003723; GO:0003729; GO:0005634; GO:0006397; GO:0008380; GO:0021954; GO:0030182; GO:0051252; GO:0120163; GO:1902667; GO:1990825 27226 XM_029332764.2 1215 152 972 547 1687 Q9ULV0 0 Unconventional myosin-Vb Homo sapiens (Human) actin filament organization [GO:0007015]; endosomal transport [GO:0016197]; protein transport [GO:0015031]; renal water homeostasis [GO:0003091]; vesicle transport along actin filament [GO:0030050]; vesicle-mediated transport [GO:0016192] GO:0000146; GO:0003091; GO:0005516; GO:0005524; GO:0005737; GO:0007015; GO:0015031; GO:0015629; GO:0016192; GO:0016197; GO:0016459; GO:0030050; GO:0030659; GO:0031267; GO:0031982; GO:0032991; GO:0045179; GO:0051015; GO:0070062 27227 XM_029332764.2 1215 152 972 547 1687 Q9ULV0 1.41e-112 Unconventional myosin-Vb Homo sapiens (Human) actin filament organization [GO:0007015]; endosomal transport [GO:0016197]; protein transport [GO:0015031]; renal water homeostasis [GO:0003091]; vesicle transport along actin filament [GO:0030050]; vesicle-mediated transport [GO:0016192] GO:0000146; GO:0003091; GO:0005516; GO:0005524; GO:0005737; GO:0007015; GO:0015031; GO:0015629; GO:0016192; GO:0016197; GO:0016459; GO:0030050; GO:0030659; GO:0031267; GO:0031982; GO:0032991; GO:0045179; GO:0051015; GO:0070062 27228 XM_044320640.1 182 141 133 131 381 NA NA NA NA NA NA 27229 XM_044318628.1 165 0 184 0 0 Q8CAE2 1.06e-61 Small RNA 2'-O-methyltransferase (EC 2.1.1.n8) (HEN1 methyltransferase homolog 1) (mHEN1) Mus musculus (Mouse) piRNA processing [GO:0034587]; RNA methylation [GO:0001510]; siRNA processing [GO:0030422] GO:0001510; GO:0003723; GO:0005634; GO:0005737; GO:0005829; GO:0008171; GO:0008173; GO:0030422; GO:0034587; GO:0043186; GO:0046872; GO:0090486 27230 XM_044313235.1 187 125 150 169 400 O95602 0 DNA-directed RNA polymerase I subunit RPA1 (RNA polymerase I subunit A1) (EC 2.7.7.6) (A190) (DNA-directed RNA polymerase I largest subunit) (DNA-directed RNA polymerase I subunit A) (RNA polymerase I 194 kDa subunit) (RPA194) Homo sapiens (Human) negative regulation of protein localization to nucleolus [GO:1904750] GO:0001054; GO:0003677; GO:0003682; GO:0005654; GO:0005694; GO:0005736; GO:0046872; GO:1904750 27231 XM_044313235.1 187 125 150 169 400 O95602 5.56e-48 DNA-directed RNA polymerase I subunit RPA1 (RNA polymerase I subunit A1) (EC 2.7.7.6) (A190) (DNA-directed RNA polymerase I largest subunit) (DNA-directed RNA polymerase I subunit A) (RNA polymerase I 194 kDa subunit) (RPA194) Homo sapiens (Human) negative regulation of protein localization to nucleolus [GO:1904750] GO:0001054; GO:0003677; GO:0003682; GO:0005654; GO:0005694; GO:0005736; GO:0046872; GO:1904750 27232 XM_044313007.1 0 0 0 10 0 NA NA NA NA NA NA 27233 XM_044315799.1 1 11 7 13 36 NA NA NA NA NA NA 27234 XM_029357217.2 274 243 165 325 305 Q8AVP1 4.2e-131 Ribosome production factor 1 (Brix domain-containing protein 5) (Ribosome biogenesis protein RPF1) Xenopus laevis (African clawed frog) rRNA processing [GO:0006364] GO:0003723; GO:0005730; GO:0006364; GO:0042134 27235 XM_029344583.2 8403 6428 5984 4628 3941 NA NA NA NA NA NA 27236 XM_044321938.1 71 11 233 164 36 NA NA NA NA NA NA 27237 XM_044325772.1 4 14 4 11 30 NA NA NA NA NA NA 27238 XM_044324344.1 628 931 1058 1353 1296 P07949 5.19e-72 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; axon guidance [GO:0007411]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; lymphocyte migration into lymphoid organs [GO:0097021]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; posterior midgut development [GO:0007497]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006468; GO:0006919; GO:0007156; GO:0007158; GO:0007165; GO:0007169; GO:0007411; GO:0007497; GO:0009410; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0038023; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0097021; GO:0098797; GO:2001241 27239 XR_006395615.1 12 33 49 13 60 NA NA NA NA NA NA 27240 XM_044324217.1 196 143 17 13 12 Q8K2J9 4.16e-69 BTB/POZ domain-containing protein 6 Mus musculus (Mouse) neurogenesis [GO:0022008] GO:0005829; GO:0022008 27241 XM_044322901.1 78 0 119 181 177 Q95SX7 6.91e-26 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 27242 XM_029349765.2 0 0 0 16 0 NA NA NA NA NA NA 27243 XM_044324262.1 5 0 3 1 9 NA NA NA NA NA NA 27244 XM_029348690.2 387 418 152 158 273 Q9CPW0 3.32e-80 Contactin-associated protein-like 2 (Cell recognition molecule Caspr2) Mus musculus (Mouse) action potential initiation [GO:0099610]; adult behavior [GO:0030534]; associative learning [GO:0008306]; axonogenesis [GO:0007409]; behavioral response to pain [GO:0048266]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell population proliferation [GO:0008283]; central nervous system myelination [GO:0022010]; cerebellar Purkinje cell layer morphogenesis [GO:0021692]; cerebellum development [GO:0021549]; chemical synaptic transmission [GO:0007268]; circadian sleep/wake cycle [GO:0042745]; clustering of voltage-gated potassium channels [GO:0045163]; dendrite arborization [GO:0140059]; dendritic spine development [GO:0060996]; dendritic spine maintenance [GO:0097062]; dendritic spine organization [GO:0097061]; embryonic brain development [GO:1990403]; ERK1 and ERK2 cascade [GO:0070371]; excitatory chemical synaptic transmission [GO:0098976]; excitatory postsynaptic potential [GO:0060079]; excitatory synapse assembly [GO:1904861]; fat cell differentiation [GO:0045444]; gene expression [GO:0010467]; glial cell proliferation [GO:0014009]; glutamatergic neuron differentiation [GO:1905962]; grooming behavior [GO:0007625]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; inhibitory chemical synaptic transmission [GO:0098977]; inhibitory synapse assembly [GO:1904862]; intracellular signal transduction [GO:0035556]; learning [GO:0007612]; limbic system development [GO:0021761]; locomotor rhythm [GO:0045475]; locomotory behavior [GO:0007626]; maintenance of synapse structure [GO:0099558]; mitochondrion organization [GO:0007005]; motor behavior [GO:0061744]; multicellular organism growth [GO:0035264]; myelination [GO:0042552]; negative regulation of neuronal action potential [GO:1904456]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; neural precursor cell proliferation [GO:0061351]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process [GO:0050905]; neuromuscular process controlling posture [GO:0050884]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuron recognition [GO:0008038]; neuronal action potential [GO:0019228]; positive regulation of gap junction assembly [GO:1903598]; positive regulation of neuronal action potential [GO:1904457]; postsynaptic density organization [GO:0097106]; protein kinase B signaling [GO:0043491]; protein localization [GO:0008104]; protein localization to juxtaparanode region of axon [GO:0071205]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; response to dietary excess [GO:0002021]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to interleukin-17 [GO:0097396]; response to light intensity [GO:0009642]; response to mechanical stimulus [GO:0009612]; response to metformin [GO:1901558]; response to odorant [GO:1990834]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; rhythmic behavior [GO:0007622]; social behavior [GO:0035176]; TOR signaling [GO:0031929]; transmission of nerve impulse [GO:0019226]; vocal learning [GO:0042297]; vocalization behavior [GO:0071625]; walking behavior [GO:0090659] GO:0000902; GO:0001701; GO:0002021; GO:0005769; GO:0005794; GO:0006954; GO:0007005; GO:0007155; GO:0007268; GO:0007409; GO:0007612; GO:0007622; GO:0007625; GO:0007626; GO:0008038; GO:0008076; GO:0008104; GO:0008283; GO:0008306; GO:0009408; GO:0009410; GO:0009612; GO:0009642; GO:0009725; GO:0009986; GO:0010033; GO:0010467; GO:0014009; GO:0016020; GO:0019226; GO:0019228; GO:0019899; GO:0021549; GO:0021692; GO:0021761; GO:0022010; GO:0030165; GO:0030424; GO:0030425; GO:0030534; GO:0030673; GO:0031175; GO:0031929; GO:0032229; GO:0033010; GO:0035176; GO:0035264; GO:0035556; GO:0042297; GO:0042552; GO:0042734; GO:0042745; GO:0043005; GO:0043025; GO:0043194; GO:0043491; GO:0044224; GO:0044309; GO:0044853; GO:0045163; GO:0045202; GO:0045444; GO:0045475; GO:0048265; GO:0048266; GO:0048787; GO:0048812; GO:0050884; GO:0050905; GO:0060076; GO:0060079; GO:0060996; GO:0061351; GO:0061744; GO:0070371; GO:0071205; GO:0071625; GO:0090659; GO:0097061; GO:0097062; GO:0097106; GO:0097396; GO:0098529; GO:0098793; GO:0098794; GO:0098976; GO:0098977; GO:0098978; GO:0098982; GO:0099072; GO:0099558; GO:0099610; GO:0140059; GO:0150048; GO:1901558; GO:1903598; GO:1904456; GO:1904457; GO:1904861; GO:1904862; GO:1905962; GO:1990403; GO:1990834 27245 XM_029342252.2 529 509 307 546 447 C3ZQF9 1.74e-25 QRFP-like peptide receptor Branchiostoma floridae (Florida lancelet) (Amphioxus) cellular response to peptide [GO:1901653]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:1901653 27246 XR_006396348.1 64 48 77 127 107 NA NA NA NA NA NA 27247 XM_044327406.1 5560 3870 3069 4619 4098 O42478 4.42e-165 Transducin-like enhancer protein 4 (Enhancer of split groucho-like protein 2) (ESG2) (xESG2) (Grg-4) (XGrg-4) (Groucho-related protein 4) Xenopus laevis (African clawed frog) mesoderm formation [GO:0001707]; negative regulation of transcription by RNA polymerase II [GO:0000122] GO:0000122; GO:0001707; GO:0003714; GO:0005654; GO:0017053 27248 XM_044327406.1 5560 3870 3069 4619 4098 O42478 1.78e-53 Transducin-like enhancer protein 4 (Enhancer of split groucho-like protein 2) (ESG2) (xESG2) (Grg-4) (XGrg-4) (Groucho-related protein 4) Xenopus laevis (African clawed frog) mesoderm formation [GO:0001707]; negative regulation of transcription by RNA polymerase II [GO:0000122] GO:0000122; GO:0001707; GO:0003714; GO:0005654; GO:0017053 27249 XM_029336194.2 1270 1615 457 1096 659 NA NA NA NA NA NA 27250 XM_029347813.2 57 0 0 20 85 Q96RS0 7.92e-96 Trimethylguanosine synthase (EC 2.1.1.-) (CLL-associated antigen KW-2) (Cap-specific guanine-N2 methyltransferase) (Hepatocellular carcinoma-associated antigen 137) (Nuclear receptor coactivator 6-interacting protein) (PRIP-interacting protein with methyltransferase motif) (PIMT) (PIPMT) Homo sapiens (Human) 7-methylguanosine cap hypermethylation [GO:0036261]; 7-methylguanosine RNA capping [GO:0009452]; ribonucleoprotein complex biogenesis [GO:0022613]; spliceosomal snRNP assembly [GO:0000387] GO:0000387; GO:0005615; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0008173; GO:0009452; GO:0015030; GO:0022613; GO:0030532; GO:0036261; GO:0071164 27251 XM_029357064.2 389 168 96 125 143 NA NA NA NA NA NA 27252 XM_029348683.2 39 36 17 17 33 Q91W96 1.86e-97 Anaphase-promoting complex subunit 4 (APC4) (Cyclosome subunit 4) Mus musculus (Mouse) anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell cycle [GO:0007049]; cell division [GO:0051301]; protein K11-linked ubiquitination [GO:0070979]; regulation of mitotic metaphase/anaphase transition [GO:0030071] GO:0005634; GO:0005680; GO:0007049; GO:0019903; GO:0030071; GO:0031145; GO:0034399; GO:0051301; GO:0070979 27253 XR_006393422.1 300 418 200 354 230 NA NA NA NA NA NA 27254 XR_006392408.1 124 82 0 143 0 NA NA NA NA NA NA 27255 XR_006395661.1 34 35 87 107 155 NA NA NA NA NA NA 27256 XM_029330808.2 1930 1558 1242 1677 579 NA NA NA NA NA NA 27257 XM_044326212.1 6 0 0 0 36 NA NA NA NA NA NA 27258 XM_029341926.2 0 12 0 0 63 P97677 6.84e-84 Delta-like protein 1 (Drosophila Delta homolog 1) (Delta1) Rattus norvegicus (Rat) astrocyte development [GO:0014002]; auditory receptor cell fate commitment [GO:0009912]; cell fate determination [GO:0001709]; cell-cell signaling [GO:0007267]; cerebellar molecular layer formation [GO:0021688]; cerebellar Purkinje cell layer structural organization [GO:0021693]; clathrin-dependent endocytosis [GO:0072583]; compartment pattern specification [GO:0007386]; determination of left/right symmetry [GO:0007368]; endothelial tip cell fate specification [GO:0097102]; energy homeostasis [GO:0097009]; heart looping [GO:0001947]; inhibition of neuroepithelial cell differentiation [GO:0002085]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear development [GO:0048839]; lateral inhibition [GO:0046331]; left/right axis specification [GO:0070986]; loop of Henle development [GO:0072070]; marginal zone B cell differentiation [GO:0002315]; myeloid cell differentiation [GO:0030099]; negative regulation of cardiac muscle cell differentiation [GO:2000726]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal cell differentiation [GO:0045605]; negative regulation of epithelial cell differentiation [GO:0030857]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of inner ear auditory receptor cell differentiation [GO:0045608]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of Notch signaling pathway [GO:0045746]; nephron development [GO:0072006]; nervous system development [GO:0007399]; neuroepithelial cell differentiation [GO:0060563]; neuron differentiation [GO:0030182]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; Notch signaling pathway involved in arterial endothelial cell fate commitment [GO:0060853]; organ growth [GO:0035265]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endocytosis [GO:0045807]; positive regulation of gene expression [GO:0010628]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of skeletal muscle tissue growth [GO:0048633]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proximal tubule development [GO:0072014]; proximal/distal pattern formation [GO:0009954]; regulation of blood pressure [GO:0008217]; regulation of cell adhesion [GO:0030155]; regulation of cell division [GO:0051302]; regulation of growth [GO:0040008]; regulation of neurogenesis [GO:0050767]; regulation of skeletal muscle tissue growth [GO:0048631]; regulation of somitogenesis [GO:0014807]; regulation of vascular endothelial growth factor signaling pathway [GO:1900746]; retina development in camera-type eye [GO:0060041]; retina morphogenesis in camera-type eye [GO:0060042]; skeletal muscle tissue growth [GO:0048630]; skin epidermis development [GO:0098773]; somite specification [GO:0001757]; somitogenesis [GO:0001756]; spinal cord development [GO:0021510]; type B pancreatic cell development [GO:0003323] GO:0001709; GO:0001756; GO:0001757; GO:0001947; GO:0002085; GO:0002315; GO:0003323; GO:0005112; GO:0005509; GO:0005886; GO:0005912; GO:0007219; GO:0007267; GO:0007368; GO:0007386; GO:0007399; GO:0008217; GO:0008284; GO:0008285; GO:0009912; GO:0009954; GO:0010628; GO:0014002; GO:0014807; GO:0016324; GO:0021510; GO:0021688; GO:0021693; GO:0030099; GO:0030155; GO:0030182; GO:0030857; GO:0030957; GO:0031410; GO:0032693; GO:0034351; GO:0035265; GO:0040008; GO:0042491; GO:0045121; GO:0045596; GO:0045605; GO:0045608; GO:0045638; GO:0045662; GO:0045665; GO:0045746; GO:0045747; GO:0045807; GO:0045944; GO:0046331; GO:0048018; GO:0048630; GO:0048631; GO:0048633; GO:0048665; GO:0048839; GO:0050767; GO:0051302; GO:0060041; GO:0060042; GO:0060563; GO:0060853; GO:0070986; GO:0072006; GO:0072014; GO:0072070; GO:0072583; GO:0097009; GO:0097102; GO:0097110; GO:0097150; GO:0098773; GO:1900746; GO:1903672; GO:2000726 27259 XM_044324252.1 0 0 16 0 88 Q4R6I5 1.55e-25 Clathrin heavy chain linker domain-containing protein 1 Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA NA 27260 XM_029347229.2 6485 9984 4849 5041 5312 Q8BHN3 0 Neutral alpha-glucosidase AB (EC 3.2.1.207) (Alpha-glucosidase 2) (Glucosidase II subunit alpha) Mus musculus (Mouse) carbohydrate metabolic process [GO:0005975]; N-glycan processing [GO:0006491] GO:0004553; GO:0005783; GO:0005794; GO:0005975; GO:0006491; GO:0015926; GO:0017177; GO:0030246; GO:0033919; GO:0042470; GO:0043231; GO:0090599 27261 XM_029343354.2 13527 15910 12994 12797 10304 Q9V9J3 0 Tyrosine-protein kinase Src42A (EC 2.7.10.2) (Tyrosine-protein kinase Src41) (Dsrc41) Drosophila melanogaster (Fruit fly) actin filament bundle assembly [GO:0051017]; adherens junction organization [GO:0034332]; apoptotic cell clearance [GO:0043277]; axon guidance [GO:0007411]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; compound eye development [GO:0048749]; defense response to bacterium [GO:0042742]; dorsal closure [GO:0007391]; dorsal closure, spreading of leading edge cells [GO:0007395]; epithelial cell-cell adhesion [GO:0090136]; hydrogen peroxide mediated signaling pathway [GO:0071588]; imaginal disc fusion, thorax closure [GO:0046529]; imaginal disc-derived wing morphogenesis [GO:0007476]; innate immune response [GO:0045087]; intestinal stem cell homeostasis [GO:0036335]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of synaptic assembly at neuromuscular junction [GO:0045886]; open tracheal system development [GO:0007424]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of inflammatory response to wounding [GO:0106016]; positive regulation of sevenless signaling pathway [GO:0045874]; protein phosphorylation [GO:0006468]; regulation of synaptic plasticity [GO:0048167]; salivary gland morphogenesis [GO:0007435]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0004713; GO:0004715; GO:0005102; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006468; GO:0007169; GO:0007391; GO:0007395; GO:0007411; GO:0007424; GO:0007435; GO:0007476; GO:0016477; GO:0018108; GO:0030154; GO:0031234; GO:0034332; GO:0036335; GO:0042059; GO:0042742; GO:0043277; GO:0045087; GO:0045742; GO:0045874; GO:0045886; GO:0046529; GO:0048167; GO:0048749; GO:0051017; GO:0070374; GO:0071588; GO:0090136; GO:0106016 27262 XM_029338096.2 454 159 184 729 269 Q7ZXK9 0 Notchless protein homolog 1 Xenopus laevis (African clawed frog) Notch signaling pathway [GO:0007219] GO:0005730; GO:0007219 27263 XM_044326712.1 249 202 180 291 189 B8VIW9 0 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 27264 XM_044326712.1 249 202 180 291 189 B8VIW9 0 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 27265 XM_044326712.1 249 202 180 291 189 B8VIW9 6.49e-63 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 27266 XM_029327339.2 983 1608 923 1253 665 Q5R988 1.49e-78 Ras-related protein Rap-2a (EC 3.6.5.2) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) actin cytoskeleton reorganization [GO:0031532]; cellular response to xenobiotic stimulus [GO:0071466]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of cell migration [GO:0030336]; positive regulation of protein autophosphorylation [GO:0031954]; protein localization [GO:0008104]; protein localization to plasma membrane [GO:0072659]; Rap protein signal transduction [GO:0032486]; regulation of dendrite morphogenesis [GO:0048814]; regulation of JNK cascade [GO:0046328]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; regulation of synapse assembly [GO:0051963] GO:0000287; GO:0003924; GO:0003925; GO:0005525; GO:0005829; GO:0005886; GO:0008104; GO:0019003; GO:0030033; GO:0030336; GO:0030496; GO:0031532; GO:0031954; GO:0032486; GO:0045184; GO:0046328; GO:0048814; GO:0051963; GO:0055038; GO:0071466; GO:0072659; GO:0098685; GO:0099072 27267 XR_006394439.1 26 63 20 30 113 NA NA NA NA NA NA 27268 XM_044326988.1 181 142 174 323 300 NA NA NA NA NA NA 27269 XM_044326641.1 784 687 430 743 15 Q9JHZ4 7.67e-45 GRIP1-associated protein 1 (GRASP-1) [Cleaved into: GRASP-1 C-terminal chain (30kDa C-terminus form)] Rattus norvegicus (Rat) negative regulation of protein localization [GO:1903828]; negative regulation of receptor clustering [GO:1903910]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; regulation of modification of synaptic structure [GO:1905244]; regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0099152]; regulation of recycling endosome localization within postsynapse [GO:0099158] GO:0005085; GO:0005654; GO:0005829; GO:0014069; GO:0016020; GO:0030424; GO:0030425; GO:0035255; GO:0042734; GO:0042802; GO:0043025; GO:0045202; GO:0055038; GO:0098837; GO:0098887; GO:0098978; GO:0098998; GO:0099152; GO:0099158; GO:1903828; GO:1903910; GO:1905244 27270 XM_044326641.1 784 687 430 743 15 Q9JHZ4 9.02e-25 GRIP1-associated protein 1 (GRASP-1) [Cleaved into: GRASP-1 C-terminal chain (30kDa C-terminus form)] Rattus norvegicus (Rat) negative regulation of protein localization [GO:1903828]; negative regulation of receptor clustering [GO:1903910]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; regulation of modification of synaptic structure [GO:1905244]; regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0099152]; regulation of recycling endosome localization within postsynapse [GO:0099158] GO:0005085; GO:0005654; GO:0005829; GO:0014069; GO:0016020; GO:0030424; GO:0030425; GO:0035255; GO:0042734; GO:0042802; GO:0043025; GO:0045202; GO:0055038; GO:0098837; GO:0098887; GO:0098978; GO:0098998; GO:0099152; GO:0099158; GO:1903828; GO:1903910; GO:1905244 27271 XM_044310262.1 0 3 5 0 6 Q09575 2.73e-36 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 27272 XM_044316337.1 455 1359 439 396 125 NA NA NA NA NA NA 27273 XR_006397527.1 0 0 5 5 17 NA NA NA NA NA NA 27274 XM_029344228.2 148 20 0 312 377 Q02410 1.13e-133 Amyloid-beta A4 precursor protein-binding family A member 1 (Adapter protein X11alpha) (Neuron-specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint-1) Homo sapiens (Human) axo-dendritic transport [GO:0008088]; cell adhesion [GO:0007155]; chemical synaptic transmission [GO:0007268]; gamma-aminobutyric acid secretion [GO:0014051]; glutamate secretion [GO:0014047]; in utero embryonic development [GO:0001701]; intracellular protein transport [GO:0006886]; locomotory behavior [GO:0007626]; multicellular organism growth [GO:0035264]; nervous system development [GO:0007399]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; protein-containing complex assembly [GO:0065003]; regulation of gene expression [GO:0010468] GO:0001540; GO:0001701; GO:0005634; GO:0005737; GO:0005794; GO:0005829; GO:0005886; GO:0006886; GO:0007155; GO:0007268; GO:0007399; GO:0007626; GO:0008021; GO:0008088; GO:0010468; GO:0014047; GO:0014051; GO:0035264; GO:0043197; GO:0048471; GO:0048787; GO:0065003; GO:0098685; GO:0098978; GO:0099171 27275 XM_029335309.2 2807 2652 1555 2186 1765 Q6GL11 2.62e-59 Charged multivesicular body protein 4b (Chromatin-modifying protein 4b) (CHMP4b) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) exit from mitosis [GO:0010458]; membrane fission [GO:0090148]; mitotic cytokinesis [GO:0000281]; nuclear membrane reassembly [GO:0031468]; protein transport [GO:0015031]; vacuolar transport [GO:0007034] GO:0000281; GO:0000815; GO:0005635; GO:0005829; GO:0007034; GO:0010458; GO:0015031; GO:0030496; GO:0031468; GO:0031902; GO:0090148 27276 XM_044329199.1 282 180 194 1496 314 Q0KK59 1.94e-116 Protein unc-79 homolog Mus musculus (Mouse) adult behavior [GO:0030534]; behavioral response to ethanol [GO:0048149]; multicellular organism growth [GO:0035264] GO:0005886; GO:0030534; GO:0035264; GO:0048149 27277 XM_044329199.1 282 180 194 1496 314 Q0KK59 1.8e-111 Protein unc-79 homolog Mus musculus (Mouse) adult behavior [GO:0030534]; behavioral response to ethanol [GO:0048149]; multicellular organism growth [GO:0035264] GO:0005886; GO:0030534; GO:0035264; GO:0048149 27278 XM_044329199.1 282 180 194 1496 314 Q0KK59 8.43e-34 Protein unc-79 homolog Mus musculus (Mouse) adult behavior [GO:0030534]; behavioral response to ethanol [GO:0048149]; multicellular organism growth [GO:0035264] GO:0005886; GO:0030534; GO:0035264; GO:0048149 27279 XM_044329199.1 282 180 194 1496 314 Q0KK59 3.43e-21 Protein unc-79 homolog Mus musculus (Mouse) adult behavior [GO:0030534]; behavioral response to ethanol [GO:0048149]; multicellular organism growth [GO:0035264] GO:0005886; GO:0030534; GO:0035264; GO:0048149 27280 XR_006393617.1 78 169 33 70 32 NA NA NA NA NA NA 27281 XM_029345589.2 1558 515 595 1349 1732 P82252 1.4e-140 b(0,+)-type amino acid transporter 1 (b(0,+)AT) (Glycoprotein-associated amino acid transporter b0,+AT1) (Solute carrier family 7 member 9) Rattus norvegicus (Rat) amino acid transport [GO:0006865]; L-cystine transport [GO:0015811]; neutral amino acid transport [GO:0015804] GO:0005886; GO:0006865; GO:0015171; GO:0015175; GO:0015179; GO:0015184; GO:0015804; GO:0015811; GO:0016324; GO:0031526; GO:0042605 27282 XR_006391568.1 159 97 105 273 213 NA NA NA NA NA NA 27283 XM_029339404.2 173 87 41 358 346 Q90YH9 1.97e-101 Testin Gallus gallus (Chicken) negative regulation of cell population proliferation [GO:0008285] GO:0005737; GO:0005829; GO:0005886; GO:0005925; GO:0008270; GO:0008285; GO:0032991 27284 XM_044307445.1 18 40 0 1 0 Q8BZM0 9.08e-40 Kelch-like protein 12 (CUL3-interacting protein 1) Mus musculus (Mouse) COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; protein monoubiquitination [GO:0006513]; Wnt signaling pathway [GO:0016055] GO:0006513; GO:0006888; GO:0014029; GO:0014032; GO:0016055; GO:0030127; GO:0030134; GO:0031463; GO:0034451; GO:0042802; GO:0043231; GO:0048208 27285 XM_044317590.1 2 0 6 10 14 NA NA NA NA NA NA 27286 XR_006396729.1 38 55 22 22 133 NA NA NA NA NA NA 27287 XM_044324272.1 88 90 259 395 539 P0C6B8 1.43e-128 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 27288 XM_044324272.1 88 90 259 395 539 P0C6B8 6.72e-123 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 27289 XM_044324272.1 88 90 259 395 539 P0C6B8 2.83e-104 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 27290 XM_044324272.1 88 90 259 395 539 P0C6B8 1.52e-103 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 27291 XM_029339845.2 462 200 342 216 405 Q15637 4.32e-122 Splicing factor 1 (Mammalian branch point-binding protein) (BBP) (mBBP) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Zinc finger protein 162) Homo sapiens (Human) Leydig cell differentiation [GO:0033327]; male sex determination [GO:0030238]; mRNA 3'-splice site recognition [GO:0000389]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of smooth muscle cell proliferation [GO:0048662]; nuclear body organization [GO:0030575]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of steroid biosynthetic process [GO:0050810]; spliceosomal complex assembly [GO:0000245] GO:0000245; GO:0000389; GO:0000398; GO:0003714; GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0005681; GO:0005840; GO:0008270; GO:0016604; GO:0030238; GO:0030575; GO:0033327; GO:0042802; GO:0048024; GO:0048662; GO:0050810; GO:0089701 27292 XM_029337103.2 66 0 0 56 0 Q8TCT0 1.66e-74 Ceramide kinase (hCERK) (EC 2.7.1.138) (Acylsphingosine kinase) (Lipid kinase 4) (LK4) Homo sapiens (Human) ceramide metabolic process [GO:0006672]; glycosphingolipid metabolic process [GO:0006687]; phosphorylation [GO:0016310]; sphingolipid metabolic process [GO:0006665] GO:0000287; GO:0001727; GO:0001729; GO:0005524; GO:0005737; GO:0005886; GO:0006665; GO:0006672; GO:0006687; GO:0016020; GO:0016310; GO:0102773 27293 XM_029356020.2 0 0 3 11 0 Q9ULM3 2.87e-64 YEATS domain-containing protein 2 Homo sapiens (Human) chromatin remodeling [GO:0006338]; histone acetylation [GO:0016573]; histone H3 acetylation [GO:0043966]; histone H3-K14 acetylation [GO:0044154]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of cell cycle [GO:0051726]; regulation of cell division [GO:0051302]; regulation of DNA-templated transcription [GO:0006355]; regulation of embryonic development [GO:0045995]; regulation of histone deacetylation [GO:0031063]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tubulin deacetylation [GO:0090043] GO:0000122; GO:0005634; GO:0006338; GO:0006355; GO:0006357; GO:0016573; GO:0017025; GO:0031063; GO:0035267; GO:0042393; GO:0043966; GO:0044154; GO:0045892; GO:0045995; GO:0051302; GO:0051726; GO:0072686; GO:0090043; GO:0140030; GO:0140672 27294 XM_044310626.1 0 0 1 7 3 NA NA NA NA NA NA 27295 XM_029324753.2 144 258 375 637 41 Q3T0T7 1.24e-95 GTP-binding protein SAR1b Bos taurus (Bovine) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; lipid homeostasis [GO:0055088]; lipoprotein transport [GO:0042953]; membrane organization [GO:0061024]; positive regulation of protein exit from endoplasmic reticulum [GO:0070863]; regulation of COPII vesicle coating [GO:0003400]; regulation of lipid transport [GO:0032368]; vesicle organization [GO:0016050] GO:0003400; GO:0003924; GO:0005525; GO:0005789; GO:0006886; GO:0006888; GO:0016050; GO:0030127; GO:0032368; GO:0032580; GO:0042953; GO:0046872; GO:0055088; GO:0061024; GO:0070863; GO:0070971 27296 XM_044316751.1 106 68 28 64 78 NA NA NA NA NA NA 27297 XM_044319556.1 57 33 50 67 239 P30551 3.1e-35 Cholecystokinin receptor type A (CCK-A receptor) (CCK-AR) (Cholecystokinin-1 receptor) (CCK1-R) Rattus norvegicus (Rat) actin cytoskeleton reorganization [GO:0031532]; animal organ regeneration [GO:0031100]; axonogenesis [GO:0007409]; cellular response to hormone stimulus [GO:0032870]; cholecystokinin signaling pathway [GO:0038188]; eating behavior [GO:0042755]; feeding behavior [GO:0007631]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; gastric acid secretion [GO:0001696]; insulin secretion [GO:0030073]; neuron migration [GO:0001764]; pancreas development [GO:0031016]; pancreatic juice secretion [GO:0030157]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of somatostatin secretion [GO:0090274]; reduction of food intake in response to dietary excess [GO:0002023]; regulation of calcium ion transport [GO:0051924]; regulation of hormone secretion [GO:0046883]; regulation of potassium ion transport [GO:0043266]; response to glucocorticoid [GO:0051384]; response to heat [GO:0009408]; response to lipopolysaccharide [GO:0032496]; response to nutrient [GO:0007584]; response to radiation [GO:0009314]; response to starvation [GO:0042594]; response to steroid hormone [GO:0048545]; temperature homeostasis [GO:0001659] GO:0001659; GO:0001696; GO:0001764; GO:0002023; GO:0004930; GO:0004951; GO:0005737; GO:0005764; GO:0005768; GO:0005783; GO:0005886; GO:0007186; GO:0007204; GO:0007409; GO:0007584; GO:0007631; GO:0009314; GO:0009408; GO:0016020; GO:0017046; GO:0030073; GO:0030157; GO:0030900; GO:0031016; GO:0031100; GO:0031532; GO:0032496; GO:0032870; GO:0038188; GO:0042594; GO:0042755; GO:0043195; GO:0043266; GO:0046883; GO:0048545; GO:0051384; GO:0051924; GO:0090274 27298 XM_044319556.1 57 33 50 67 239 P30551 4.87e-25 Cholecystokinin receptor type A (CCK-A receptor) (CCK-AR) (Cholecystokinin-1 receptor) (CCK1-R) Rattus norvegicus (Rat) actin cytoskeleton reorganization [GO:0031532]; animal organ regeneration [GO:0031100]; axonogenesis [GO:0007409]; cellular response to hormone stimulus [GO:0032870]; cholecystokinin signaling pathway [GO:0038188]; eating behavior [GO:0042755]; feeding behavior [GO:0007631]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; gastric acid secretion [GO:0001696]; insulin secretion [GO:0030073]; neuron migration [GO:0001764]; pancreas development [GO:0031016]; pancreatic juice secretion [GO:0030157]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of somatostatin secretion [GO:0090274]; reduction of food intake in response to dietary excess [GO:0002023]; regulation of calcium ion transport [GO:0051924]; regulation of hormone secretion [GO:0046883]; regulation of potassium ion transport [GO:0043266]; response to glucocorticoid [GO:0051384]; response to heat [GO:0009408]; response to lipopolysaccharide [GO:0032496]; response to nutrient [GO:0007584]; response to radiation [GO:0009314]; response to starvation [GO:0042594]; response to steroid hormone [GO:0048545]; temperature homeostasis [GO:0001659] GO:0001659; GO:0001696; GO:0001764; GO:0002023; GO:0004930; GO:0004951; GO:0005737; GO:0005764; GO:0005768; GO:0005783; GO:0005886; GO:0007186; GO:0007204; GO:0007409; GO:0007584; GO:0007631; GO:0009314; GO:0009408; GO:0016020; GO:0017046; GO:0030073; GO:0030157; GO:0030900; GO:0031016; GO:0031100; GO:0031532; GO:0032496; GO:0032870; GO:0038188; GO:0042594; GO:0042755; GO:0043195; GO:0043266; GO:0046883; GO:0048545; GO:0051384; GO:0051924; GO:0090274 27299 XM_029348468.2 0 0 3 110 219 C3LWF0 4.33e-23 L-threonine 3-dehydrogenase (TDH) (EC 1.1.1.103) Vibrio cholerae serotype O1 (strain M66-2) L-threonine catabolic process to glycine [GO:0019518] GO:0005737; GO:0008270; GO:0008743; GO:0019518 27300 XM_029354691.2 455 89 116 736 1047 O15992 0 Arginine kinase (AK) (EC 2.7.3.3) Anthopleura japonica (Sea anemone) phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310] GO:0004054; GO:0004111; GO:0005524; GO:0016310; GO:0046314 27301 XM_044318041.1 5 0 1 0 11 Q5BJL5 3.3e-85 Protein strawberry notch homolog 1 Rattus norvegicus (Rat) regulation of DNA-templated transcription [GO:0006355]; regulation of response to stimulus [GO:0048583] GO:0005634; GO:0006355; GO:0031490; GO:0042393; GO:0048583 27302 XM_044319312.1 160 43 5 41 29 Q9VCA2 5.45e-79 Organic cation transporter protein Drosophila melanogaster (Fruit fly) apoptotic process [GO:0006915]; ion transport [GO:0006811] GO:0006811; GO:0006915; GO:0016020; GO:0022857 27303 XM_029334937.2 281 166 0 203 221 A2AAY5 1.31e-34 SH3 and PX domain-containing protein 2B (Factor for adipocyte differentiation 49) (Tyrosine kinase substrate with four SH3 domains) Mus musculus (Mouse) adipose tissue development [GO:0060612]; bone development [GO:0060348]; cranial skeletal system development [GO:1904888]; extracellular matrix disassembly [GO:0022617]; eye development [GO:0001654]; heart development [GO:0007507]; osteoblast fate commitment [GO:0002051]; podosome assembly [GO:0071800]; positive regulation of adipose tissue development [GO:1904179]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of gene expression [GO:0010628]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of stress fiber assembly [GO:0051496]; protein localization to membrane [GO:0072657]; regulation of brood size [GO:0060378]; skeletal system development [GO:0001501]; skeletal system morphogenesis [GO:0048705]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801] GO:0001501; GO:0001654; GO:0002051; GO:0002102; GO:0005737; GO:0006801; GO:0007507; GO:0010314; GO:0010628; GO:0016176; GO:0022617; GO:0032266; GO:0040018; GO:0042169; GO:0042554; GO:0042995; GO:0045600; GO:0048705; GO:0051496; GO:0060348; GO:0060378; GO:0060612; GO:0070161; GO:0070273; GO:0071800; GO:0072657; GO:0080025; GO:1904179; GO:1904888 27304 XR_006393278.1 0 0 2 6 3 NA NA NA NA NA NA 27305 XM_044310049.1 258 310 141 203 429 P54277 3.34e-89 PMS1 protein homolog 1 (DNA mismatch repair protein PMS1) Homo sapiens (Human) mismatch repair [GO:0006298]; response to xenobiotic stimulus [GO:0009410] GO:0003677; GO:0005524; GO:0005634; GO:0006298; GO:0009410; GO:0016887; GO:0019899; GO:0030983; GO:0032300; GO:0140664 27306 XM_044310049.1 258 310 141 203 429 P54277 2.13e-38 PMS1 protein homolog 1 (DNA mismatch repair protein PMS1) Homo sapiens (Human) mismatch repair [GO:0006298]; response to xenobiotic stimulus [GO:0009410] GO:0003677; GO:0005524; GO:0005634; GO:0006298; GO:0009410; GO:0016887; GO:0019899; GO:0030983; GO:0032300; GO:0140664 27307 XM_044325540.1 696 425 657 651 1094 Q3UQI9 1.02e-131 Probable ubiquitin carboxyl-terminal hydrolase MINDY-4 (EC 3.4.19.12) (Probable deubiquitinating enzyme MINDY-4) Mus musculus (Mouse) protein K48-linked deubiquitination [GO:0071108] GO:0004843; GO:0071108; GO:1990380 27308 XM_044322115.1 4454 15925 11035 8492 10277 P12394 2.9e-128 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Gallus gallus (Chicken) hormone biosynthetic process [GO:0042446]; progesterone metabolic process [GO:0042448]; steroid biosynthetic process [GO:0006694]; steroid metabolic process [GO:0008202] GO:0004508; GO:0005506; GO:0006694; GO:0008202; GO:0016020; GO:0020037; GO:0042446; GO:0042448; GO:0047442 27309 XM_029351855.2 6381 13534 6850 8262 4846 Q6GPH4 3.98e-21 XIAP-associated factor 1 (BIRC4-binding protein) Homo sapiens (Human) apoptotic process [GO:0006915]; response to interferon-beta [GO:0035456] GO:0005654; GO:0005739; GO:0005829; GO:0006915; GO:0008270; GO:0035456 27310 XR_006391645.1 402 286 365 348 292 P51688 0 N-sulphoglucosamine sulphohydrolase (EC 3.10.1.1) (Sulfoglucosamine sulfamidase) (Sulphamidase) Homo sapiens (Human) glycosaminoglycan catabolic process [GO:0006027]; heparan sulfate proteoglycan catabolic process [GO:0030200] GO:0005539; GO:0005764; GO:0006027; GO:0008484; GO:0016250; GO:0030200; GO:0043202; GO:0046872; GO:0070062 27311 XR_006396204.1 75 15 21 29 15 NA NA NA NA NA NA 27312 XM_044320176.1 2070 1578 582 2369 977 NA NA NA NA NA NA 27313 XM_044327157.1 4 3 4 7 11 NA NA NA NA NA NA 27314 XR_006398093.1 27 1 0 8 8 NA NA NA NA NA NA 27315 XM_044329305.1 1864 996 1396 1983 1341 Q3SYV5 1.83e-55 Tetraspanin-33 (Tspan-33) Bos taurus (Bovine) NA GO:0005737; GO:0005886; GO:0005912 27316 XM_044323313.1 13 2 31 0 90 NA NA NA NA NA NA 27317 XM_044318510.1 319 573 366 19 577 Q9ULT8 0 E3 ubiquitin-protein ligase HECTD1 (EC 2.3.2.26) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1) Homo sapiens (Human) anatomical structure development [GO:0048856]; aorta development [GO:0035904]; heart valve development [GO:0003170]; natural killer cell differentiation [GO:0001779]; negative regulation of protein localization to plasma membrane [GO:1903077]; neural tube closure [GO:0001843]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein localization to plasma membrane [GO:0072659]; protein polyubiquitination [GO:0000209]; spongiotrophoblast differentiation [GO:0060708]; trophoblast giant cell differentiation [GO:0060707]; ventricular septum development [GO:0003281] GO:0000209; GO:0001779; GO:0001843; GO:0003170; GO:0003281; GO:0016607; GO:0032436; GO:0035904; GO:0043161; GO:0046872; GO:0048856; GO:0051865; GO:0060707; GO:0060708; GO:0061630; GO:0070534; GO:0072659; GO:1903077 27318 XM_044318510.1 319 573 366 19 577 Q9ULT8 2.02e-164 E3 ubiquitin-protein ligase HECTD1 (EC 2.3.2.26) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1) Homo sapiens (Human) anatomical structure development [GO:0048856]; aorta development [GO:0035904]; heart valve development [GO:0003170]; natural killer cell differentiation [GO:0001779]; negative regulation of protein localization to plasma membrane [GO:1903077]; neural tube closure [GO:0001843]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein localization to plasma membrane [GO:0072659]; protein polyubiquitination [GO:0000209]; spongiotrophoblast differentiation [GO:0060708]; trophoblast giant cell differentiation [GO:0060707]; ventricular septum development [GO:0003281] GO:0000209; GO:0001779; GO:0001843; GO:0003170; GO:0003281; GO:0016607; GO:0032436; GO:0035904; GO:0043161; GO:0046872; GO:0048856; GO:0051865; GO:0060707; GO:0060708; GO:0061630; GO:0070534; GO:0072659; GO:1903077 27319 XM_044318510.1 319 573 366 19 577 Q9ULT8 5.75e-103 E3 ubiquitin-protein ligase HECTD1 (EC 2.3.2.26) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1) Homo sapiens (Human) anatomical structure development [GO:0048856]; aorta development [GO:0035904]; heart valve development [GO:0003170]; natural killer cell differentiation [GO:0001779]; negative regulation of protein localization to plasma membrane [GO:1903077]; neural tube closure [GO:0001843]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein localization to plasma membrane [GO:0072659]; protein polyubiquitination [GO:0000209]; spongiotrophoblast differentiation [GO:0060708]; trophoblast giant cell differentiation [GO:0060707]; ventricular septum development [GO:0003281] GO:0000209; GO:0001779; GO:0001843; GO:0003170; GO:0003281; GO:0016607; GO:0032436; GO:0035904; GO:0043161; GO:0046872; GO:0048856; GO:0051865; GO:0060707; GO:0060708; GO:0061630; GO:0070534; GO:0072659; GO:1903077 27320 XM_044323144.1 69 12 11 15 45 NA NA NA NA NA NA 27321 XM_029337075.2 617 301 139 271 245 Q63248 9.56e-21 Forkhead box protein I2 (Hepatocyte nuclear factor 3 forkhead homolog 5) (HFH-5) Rattus norvegicus (Rat) anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0003700; GO:0005634; GO:0006357; GO:0009653; GO:0030154 27322 XR_006391370.1 25 43 113 4 19 NA NA NA NA NA NA 27323 XM_044325871.1 20 0 43 34 139 NA NA NA NA NA NA 27324 XM_029339924.2 121 115 158 125 68 NA NA NA NA NA NA 27325 XM_044309724.1 543 488 312 223 236 NA NA NA NA NA NA 27326 XM_029337073.2 201 124 143 199 350 A8E657 0 Alpha-aminoadipic semialdehyde synthase, mitochondrial (LKR/SDH) [Includes: Lysine ketoglutarate reductase (LKR) (LOR) (EC 1.5.1.8); Saccharopine dehydrogenase (SDH) (EC 1.5.1.9)] Bos taurus (Bovine) L-lysine catabolic process to acetyl-CoA via saccharopine [GO:0033512]; lysine biosynthetic process via aminoadipic acid [GO:0019878]; lysine catabolic process [GO:0006554] GO:0004753; GO:0005737; GO:0005739; GO:0006554; GO:0019878; GO:0033512; GO:0047130; GO:0047131 27327 XM_029327375.2 5789 3649 1418 3453 6215 NA NA NA NA NA NA 27328 XR_003826753.2 51 69 41 105 87 NA NA NA NA NA NA 27329 XM_044325194.1 77 0 0 0 114 P09917 5.33e-84 Polyunsaturated fatty acid 5-lipoxygenase (EC 1.13.11.-) (Arachidonate 5-lipoxygenase) (5-LO) (5-lipoxygenase) (EC 1.13.11.34) Homo sapiens (Human) arachidonic acid metabolic process [GO:0019369]; dendritic cell migration [GO:0036336]; glucose homeostasis [GO:0042593]; hepoxilin biosynthetic process [GO:0051122]; humoral immune response [GO:0006959]; leukocyte chemotaxis involved in inflammatory response [GO:0002232]; leukocyte migration involved in inflammatory response [GO:0002523]; leukotriene A4 biosynthetic process [GO:1901753]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; leukotriene production involved in inflammatory response [GO:0002540]; linoleic acid metabolic process [GO:0043651]; lipid oxidation [GO:0034440]; lipoxin biosynthetic process [GO:2001301]; lipoxygenase pathway [GO:0019372]; long-chain fatty acid biosynthetic process [GO:0042759]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of inflammatory response [GO:0050728]; negative regulation of response to endoplasmic reticulum stress [GO:1903573]; negative regulation of sprouting angiogenesis [GO:1903671]; negative regulation of vascular wound healing [GO:0061044]; negative regulation of wound healing [GO:0061045]; positive regulation of bone mineralization [GO:0030501]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; regulation of cellular response to oxidative stress [GO:1900407]; regulation of cytokine production involved in inflammatory response [GO:1900015]; regulation of fat cell differentiation [GO:0045598]; regulation of inflammatory response [GO:0050727]; regulation of inflammatory response to wounding [GO:0106014]; regulation of insulin secretion [GO:0050796]; regulation of reactive oxygen species biosynthetic process [GO:1903426] GO:0001937; GO:0002232; GO:0002523; GO:0002540; GO:0004051; GO:0004052; GO:0005506; GO:0005576; GO:0005615; GO:0005635; GO:0005641; GO:0005654; GO:0005829; GO:0006691; GO:0006959; GO:0016363; GO:0016525; GO:0016702; GO:0016787; GO:0019369; GO:0019370; GO:0019372; GO:0030501; GO:0031965; GO:0034440; GO:0034774; GO:0036336; GO:0036403; GO:0042593; GO:0042759; GO:0043651; GO:0045598; GO:0048471; GO:0050727; GO:0050728; GO:0050796; GO:0051122; GO:0061044; GO:0061045; GO:0106014; GO:1900015; GO:1900407; GO:1901753; GO:1903426; GO:1903573; GO:1903671; GO:1904813; GO:1904999; GO:2001301 27330 XR_006393518.1 84 109 16 30 442 NA NA NA NA NA NA 27331 XM_029335206.2 779 536 390 513 645 NA NA NA NA NA NA 27332 XR_006392402.1 24 20 21 48 39 Q4R3J0 1.77e-101 RNA 3'-terminal phosphate cyclase (RNA cyclase) (RNA-3'-phosphate cyclase) (EC 6.5.1.4) (RNA terminal phosphate cyclase domain-containing protein 1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) RNA processing [GO:0006396] GO:0003963; GO:0005524; GO:0005654; GO:0006396 27333 XR_003824565.2 52 7 80 31 239 NA NA NA NA NA NA 27334 XR_006397784.1 210 253 129 139 156 NA NA NA NA NA NA 27335 XM_029329961.2 2546 1473 1332 2667 2237 Q3UG20 1.74e-71 Inactive histone-lysine N-methyltransferase 2E (Inactive lysine N-methyltransferase 2E) (Myeloid/lymphoid or mixed-lineage leukemia protein 5 homolog) Mus musculus (Mouse) cell cycle [GO:0007049]; chromatin organization [GO:0006325]; DNA methylation [GO:0006306]; erythrocyte differentiation [GO:0030218]; neutrophil activation [GO:0042119]; neutrophil mediated immunity [GO:0002446]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; regulation of DNA-templated transcription [GO:0006355]; regulation of histone acetylation [GO:0035065]; retinoic acid receptor signaling pathway [GO:0048384] GO:0000785; GO:0000791; GO:0002446; GO:0003713; GO:0005634; GO:0005654; GO:0005737; GO:0005815; GO:0006306; GO:0006325; GO:0006355; GO:0007049; GO:0016604; GO:0016607; GO:0019899; GO:0030218; GO:0032991; GO:0034967; GO:0035064; GO:0035065; GO:0042119; GO:0042800; GO:0045893; GO:0046872; GO:0048384; GO:0070210; GO:1900087 27336 XM_029339709.2 881 339 65 138 503 NA NA NA NA NA NA 27337 XR_006391881.1 1528 1413 206 1317 3082 P97321 6.19e-70 Prolyl endopeptidase FAP (EC 3.4.21.26) (Dipeptidyl peptidase FAP) (EC 3.4.14.5) (Fibroblast activation protein alpha) (FAPalpha) (Gelatine degradation protease FAP) (EC 3.4.21.-) (Integral membrane serine protease) (Post-proline cleaving enzyme) (Serine integral membrane protease) (SIMP) (Surface-expressed protease) (Seprase) [Cleaved into: Antiplasmin-cleaving enzyme FAP, soluble form (APCE) (EC 3.4.14.5) (EC 3.4.21.-) (EC 3.4.21.26)] Mus musculus (Mouse) angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; melanocyte apoptotic process [GO:1902362]; melanocyte proliferation [GO:0097325]; negative regulation of cell proliferation involved in contact inhibition [GO:0060244]; negative regulation of extracellular matrix disassembly [GO:0010716]; negative regulation of extracellular matrix organization [GO:1903054]; positive regulation of execution phase of apoptosis [GO:1900119]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of cell cycle [GO:0051726]; regulation of collagen catabolic process [GO:0010710] GO:0001525; GO:0002020; GO:0004175; GO:0004252; GO:0005178; GO:0005615; GO:0005886; GO:0006508; GO:0007155; GO:0008233; GO:0008236; GO:0008239; GO:0009986; GO:0010710; GO:0010716; GO:0030027; GO:0031258; GO:0032587; GO:0042802; GO:0042803; GO:0043542; GO:0045177; GO:0045178; GO:0051603; GO:0051726; GO:0060244; GO:0070161; GO:0097325; GO:1900119; GO:1902362; GO:1903054; GO:1905368 27338 XM_044325490.1 117 26 11 30 134 NA NA NA NA NA NA 27339 XM_044312447.1 8 0 26 0 38 P84239 1.88e-91 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 27340 XM_044322915.1 21 437 11 98 1597 C6FG12 2.06e-29 Protein NLRC5 Ictalurus punctatus (Channel catfish) (Silurus punctatus) innate immune response [GO:0045087] GO:0005524; GO:0005737; GO:0045087 27341 XM_029333260.2 23 10 0 20 5 P26714 6.96e-60 Gamma-aminobutyric acid receptor subunit beta (GABA(A) receptor) Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004890; GO:0005230; GO:0005254; GO:0034707; GO:0045211 27342 XM_044312074.1 13 4 0 23 11 NA NA NA NA NA NA 27343 XM_044314590.1 1463 1149 838 1256 909 A0AUS0 1.66e-45 WD repeat, SAM and U-box domain-containing protein 1 Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0004842 27344 XR_003824538.2 0 0 0 0 7 NA NA NA NA NA NA 27345 XM_029356985.2 31 36 0 25 0 Q924H0 1.15e-32 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide NPFF receptor) Mus musculus (Mouse) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 27346 XM_029333638.2 465 482 202 596 666 Q90693 9.85e-140 Protein patched homolog 1 (PTC) (PTC1) Gallus gallus (Chicken) negative regulation of smoothened signaling pathway [GO:0045879]; smoothened signaling pathway [GO:0007224] GO:0005119; GO:0005886; GO:0007224; GO:0008158; GO:0045879; GO:0097108 27347 XM_029333638.2 465 482 202 596 666 Q90693 7.02e-126 Protein patched homolog 1 (PTC) (PTC1) Gallus gallus (Chicken) negative regulation of smoothened signaling pathway [GO:0045879]; smoothened signaling pathway [GO:0007224] GO:0005119; GO:0005886; GO:0007224; GO:0008158; GO:0045879; GO:0097108 27348 XM_044313075.1 5 27 25 31 29 NA NA NA NA NA NA 27349 XM_044328925.1 299 281 205 224 236 Q90415 2.55e-58 Retinoic acid receptor RXR-alpha-B (Nuclear receptor subfamily 2 group B member 1-B) (Retinoid X receptor alpha-B) Danio rerio (Zebrafish) (Brachydanio rerio) anatomical structure development [GO:0048856]; cell differentiation [GO:0030154]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; response to retinoic acid [GO:0032526]; retinoic acid receptor signaling pathway [GO:0048384] GO:0000122; GO:0000978; GO:0003700; GO:0003707; GO:0004879; GO:0006357; GO:0008270; GO:0030154; GO:0032526; GO:0044323; GO:0045944; GO:0048384; GO:0048856; GO:0090575 27350 XM_029344616.2 85 122 187 258 462 NA NA NA NA NA NA 27351 XM_029357490.2 2212 1853 1436 2730 2488 Q32N90 3.29e-104 MBT domain-containing protein 1 Xenopus laevis (African clawed frog) chromatin organization [GO:0006325]; double-strand break repair via homologous recombination [GO:0000724]; regulation of DNA-templated transcription [GO:0006355] GO:0000724; GO:0005634; GO:0006325; GO:0006355; GO:0008270; GO:0035064; GO:0035267 27352 XM_029339992.2 30 56 16 16 33 NA NA NA NA NA NA 27353 XR_006391526.1 44 0 4 189 9 NA NA NA NA NA NA 27354 XR_006395454.1 0 23 4 28 74 NA NA NA NA NA NA 27355 XR_006394172.1 0 0 0 0 12 NA NA NA NA NA NA 27356 XM_029327282.2 956 620 432 875 725 Q6NZ04 1.08e-117 Homeobox protein six1b (Homeobox protein six1a) (Sine oculis homeobox homolog 1a) (Sine oculis homeobox homolog 1b) Danio rerio (Zebrafish) (Brachydanio rerio) adenohypophysis development [GO:0021984]; apoptotic process [GO:0006915]; extraocular skeletal muscle development [GO:0002074]; inner ear development [GO:0048839]; peripheral nervous system neuron development [GO:0048935]; pharyngeal muscle development [GO:0043282]; regulation of skeletal muscle cell proliferation [GO:0014857]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal muscle fiber development [GO:0048741]; striated muscle cell differentiation [GO:0051146] GO:0000978; GO:0000981; GO:0002074; GO:0005634; GO:0005667; GO:0005737; GO:0006357; GO:0006915; GO:0014857; GO:0021984; GO:0043282; GO:0048741; GO:0048839; GO:0048935; GO:0051146 27357 XM_029330271.2 156 105 47 87 89 H1AFJ5 1.93e-41 Amiloride-sensitive sodium channel subunit alpha (Alpha-NaCH) (Epithelial Na(+) channel subunit alpha) (Alpha-ENaC) (Nonvoltage-gated sodium channel 1 subunit alpha) (SCNEA) Neoceratodus forsteri (Australian lungfish) (Ceratodus forsteri) sodium ion transmembrane transport [GO:0035725] GO:0001669; GO:0005737; GO:0015280; GO:0016324; GO:0031514; GO:0034706; GO:0035725 27358 XM_029342247.2 142882 69196 23135 91752 44935 NA NA NA NA NA NA 27359 XM_029342192.2 24 0 0 441 15 Q5VTB9 5.49e-58 E3 ubiquitin-protein ligase RNF220 (EC 2.3.2.27) (RING finger protein 220) (RING-type E3 ubiquitin transferase RNF220) Homo sapiens (Human) dorsal/ventral neural tube patterning [GO:0021904]; noradrenergic neuron development [GO:0003358]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; protein autoubiquitination [GO:0051865]; protein monoubiquitination [GO:0006513]; protein ubiquitination [GO:0016567]; regulation of transcription regulatory region DNA binding [GO:2000677] GO:0003358; GO:0004842; GO:0005634; GO:0005652; GO:0005737; GO:0006513; GO:0008013; GO:0016567; GO:0021904; GO:0032991; GO:0046872; GO:0051091; GO:0051865; GO:0061630; GO:0090263; GO:2000677 27360 XM_044320244.1 1 0 3 0 27 P17892 2.03e-59 Pancreatic lipase-related protein 2 (PL-RP2) (Cytotoxic T lymphocyte lipase) (Galactolipase) (EC 3.1.1.26) (Triacylglycerol lipase) (EC 3.1.1.3) Mus musculus (Mouse) cellular defense response [GO:0006968]; galactolipid catabolic process [GO:0019376]; intestinal lipid catabolic process [GO:0044258]; lipid catabolic process [GO:0016042]; phosphatidylcholine catabolic process [GO:0034638]; phospholipid catabolic process [GO:0009395]; phospholipid metabolic process [GO:0006644]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433] GO:0004620; GO:0004806; GO:0005509; GO:0005615; GO:0006644; GO:0006968; GO:0009395; GO:0009617; GO:0016042; GO:0016298; GO:0019376; GO:0019433; GO:0034638; GO:0042589; GO:0043005; GO:0044258; GO:0047372; GO:0047714; GO:0102549 27361 XM_044312712.1 190 191 41 73 70 NA NA NA NA NA NA 27362 XM_044328950.1 26 7 8 2 21 NA NA NA NA NA NA 27363 XM_029325167.2 312 489 455 281 442 Q6GNV7 1.11e-52 Solute carrier family 49 member 4 homolog (Disrupted in renal carcinoma protein 2 homolog) Xenopus laevis (African clawed frog) NA GO:0005765; GO:0022857 27364 XM_029345208.2 19 0 14 12 115 NA NA NA NA NA NA 27365 XM_029344014.2 1079 550 428 1019 1218 A1L1W9 1.3e-70 Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10) Danio rerio (Zebrafish) (Brachydanio rerio) aromatic amino acid transport [GO:0015801]; thyroid hormone transport [GO:0070327] GO:0005302; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0070327 27366 XM_029331920.2 9 0 0 0 0 Q7LGC8 8.61e-29 Carbohydrate sulfotransferase 3 (EC 2.8.2.17) (EC 2.8.2.21) (Chondroitin 6-O-sulfotransferase 1) (C6ST-1) (Chondroitin 6-sulfotransferase) (C6ST) (Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 0) (GST-0) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; chondroitin sulfate biosynthetic process [GO:0030206]; N-acetylglucosamine metabolic process [GO:0006044]; sulfur compound metabolic process [GO:0006790]; T cell homeostasis [GO:0043029] GO:0000139; GO:0001517; GO:0005802; GO:0005975; GO:0006044; GO:0006790; GO:0008459; GO:0030206; GO:0043029; GO:0050698 27367 XM_029350495.2 61 48 64 60 53 NA NA NA NA NA NA 27368 XM_029355462.2 2127 1654 615 1423 1422 NA NA NA NA NA NA 27369 XM_029346147.2 243 171 141 122 265 NA NA NA NA NA NA 27370 XM_029339338.2 35 9 8 40 69 O88871 2.93e-124 Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51) Rattus norvegicus (Rat) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; gamma-aminobutyric acid signaling pathway [GO:0007214]; neuron-glial cell signaling [GO:0150099]; synaptic transmission, GABAergic [GO:0051932] GO:0004888; GO:0004965; GO:0005737; GO:0005886; GO:0007193; GO:0007214; GO:0016020; GO:0030425; GO:0038039; GO:0042734; GO:0043005; GO:0043204; GO:0045211; GO:0046982; GO:0051932; GO:0098978; GO:0098982; GO:0150099; GO:1902710; GO:1902712 27371 XM_029333776.2 0 0 56 0 0 Q7TN88 3.26e-68 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 27372 XM_029333776.2 0 0 56 0 0 Q7TN88 3.18e-49 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 27373 XM_029341216.2 118 78 34 219 148 NA NA NA NA NA NA 27374 XM_044326692.1 915 536 2150 2015 453 NA NA NA NA NA NA 27375 XR_003827030.2 45 25 31 52 75 NA NA NA NA NA NA 27376 XR_006397836.1 95 21 53 12 244 NA NA NA NA NA NA 27377 XR_006397291.1 42 42 19 41 30 NA NA NA NA NA NA 27378 XM_044317012.1 327 803 191 1478 1633 Q14192 3.85e-71 Four and a half LIM domains protein 2 (FHL-2) (LIM domain protein DRAL) (Skeletal muscle LIM-protein 3) (SLIM-3) Homo sapiens (Human) atrial cardiac muscle cell development [GO:0055014]; heart trabecula formation [GO:0060347]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of transcription by RNA polymerase II [GO:0000122]; osteoblast differentiation [GO:0001649]; response to hormone [GO:0009725]; ventricular cardiac muscle cell development [GO:0055015] GO:0000122; GO:0001649; GO:0003712; GO:0003714; GO:0005634; GO:0005654; GO:0005925; GO:0008134; GO:0009725; GO:0030018; GO:0042802; GO:0043066; GO:0043425; GO:0046872; GO:0055014; GO:0055015; GO:0060347; GO:0070885 27379 XM_044317012.1 327 803 191 1478 1633 Q14192 9.91e-30 Four and a half LIM domains protein 2 (FHL-2) (LIM domain protein DRAL) (Skeletal muscle LIM-protein 3) (SLIM-3) Homo sapiens (Human) atrial cardiac muscle cell development [GO:0055014]; heart trabecula formation [GO:0060347]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of transcription by RNA polymerase II [GO:0000122]; osteoblast differentiation [GO:0001649]; response to hormone [GO:0009725]; ventricular cardiac muscle cell development [GO:0055015] GO:0000122; GO:0001649; GO:0003712; GO:0003714; GO:0005634; GO:0005654; GO:0005925; GO:0008134; GO:0009725; GO:0030018; GO:0042802; GO:0043066; GO:0043425; GO:0046872; GO:0055014; GO:0055015; GO:0060347; GO:0070885 27380 XM_044317012.1 327 803 191 1478 1633 Q14192 3.03e-22 Four and a half LIM domains protein 2 (FHL-2) (LIM domain protein DRAL) (Skeletal muscle LIM-protein 3) (SLIM-3) Homo sapiens (Human) atrial cardiac muscle cell development [GO:0055014]; heart trabecula formation [GO:0060347]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of transcription by RNA polymerase II [GO:0000122]; osteoblast differentiation [GO:0001649]; response to hormone [GO:0009725]; ventricular cardiac muscle cell development [GO:0055015] GO:0000122; GO:0001649; GO:0003712; GO:0003714; GO:0005634; GO:0005654; GO:0005925; GO:0008134; GO:0009725; GO:0030018; GO:0042802; GO:0043066; GO:0043425; GO:0046872; GO:0055014; GO:0055015; GO:0060347; GO:0070885 27381 XM_029341191.2 22 23 10 13 21 NA NA NA NA NA NA 27382 XM_044320879.1 21 31 0 6 16 NA NA NA NA NA NA 27383 XM_044315527.1 63 61 20 33 21 NA NA NA NA NA NA 27384 XM_029336309.2 1365 1078 841 736 996 Q9XWN7 1.51e-43 Nucleoside hydrolase (EC 3.2.2.-) (EC 3.2.2.1) (EC 3.2.2.2) (EC 3.2.2.3) (EC 3.2.2.7) (EC 3.2.2.8) Caenorhabditis elegans nucleobase-containing compound metabolic process [GO:0006139]; organonitrogen compound metabolic process [GO:1901564] GO:0006139; GO:0016799; GO:0046872; GO:1901564 27385 XM_044325164.1 42 14 0 10 40 NA NA NA NA NA NA 27386 XM_044324075.1 0 23 41 58 58 NA NA NA NA NA NA 27387 XM_044324823.1 15 638 427 904 624 NA NA NA NA NA NA 27388 XM_044312981.1 46 0 0 0 32 NA NA NA NA NA NA 27389 XM_044326861.1 21 122 102 45 43 NA NA NA NA NA NA 27390 XR_006394630.1 0 0 0 0 11 NA NA NA NA NA NA 27391 XM_029332622.2 820 250 185 475 319 NA NA NA NA NA NA 27392 XR_003824924.2 44 19 38 9 9 F4KD68 4.14e-35 WAT1-related protein At5g45370 Arabidopsis thaliana (Mouse-ear cress) NA GO:0005886; GO:0022857 27393 XM_029324475.2 186 221 160 293 307 NA NA NA NA NA NA 27394 XM_029344552.2 3917 10677 6721 13373 9425 NA NA NA NA NA NA 27395 XM_029344091.2 18 16 0 51 29 Q6RI86 2.59e-82 Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Wasabi receptor) Rattus norvegicus (Rat) calcium ion transmembrane import into cytosol [GO:0097553]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cell surface receptor signaling pathway [GO:0007166]; cellular calcium ion homeostasis [GO:0006874]; cellular response to caffeine [GO:0071313]; cellular response to carbon dioxide [GO:0071244]; cellular response to cold [GO:0070417]; cellular response to heat [GO:0034605]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to organic substance [GO:0071310]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; ion transmembrane transport [GO:0034220]; positive regulation of anion transport [GO:1903793]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of sensory perception of pain [GO:1904058]; protein homotetramerization [GO:0051289]; regulation of blood circulation [GO:1903522]; regulation of neuronal action potential [GO:0098908]; response to cold [GO:0009409]; response to hydrogen peroxide [GO:0042542]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; sensory perception of pain [GO:0019233]; thermoception [GO:0050955]; transmembrane transport [GO:0055085]; urinary bladder smooth muscle contraction [GO:0014832] GO:0005216; GO:0005245; GO:0005262; GO:0005886; GO:0006816; GO:0006874; GO:0007166; GO:0009409; GO:0009410; GO:0010033; GO:0014070; GO:0014832; GO:0015267; GO:0015278; GO:0016324; GO:0019233; GO:0030424; GO:0032421; GO:0034220; GO:0034605; GO:0035774; GO:0042542; GO:0042802; GO:0048265; GO:0050955; GO:0050966; GO:0050968; GO:0050974; GO:0051289; GO:0055085; GO:0070301; GO:0070417; GO:0070588; GO:0071244; GO:0071310; GO:0071313; GO:0097553; GO:0097604; GO:0098908; GO:1903522; GO:1903793; GO:1904058; GO:1990760 27396 XM_029330746.2 1147 1264 839 986 1152 Q9D8B6 8.32e-29 Protein FAM210B, mitochondrial Mus musculus (Mouse) cellular response to estradiol stimulus [GO:0071392]; erythrocyte maturation [GO:0043249]; positive regulation of erythrocyte differentiation [GO:0045648] GO:0005739; GO:0005741; GO:0016020; GO:0043249; GO:0045648; GO:0071392 27397 XM_029356042.2 538 365 215 303 362 Q32PP9 5.57e-23 Transcription factor Sox-14 Danio rerio (Zebrafish) (Brachydanio rerio) anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; hypothalamus development [GO:0021854]; regulation of DNA-templated transcription [GO:0006355] GO:0000978; GO:0000981; GO:0005634; GO:0006355; GO:0009653; GO:0021854; GO:0030154 27398 XM_044316414.1 699 524 551 839 485 NA NA NA NA NA NA 27399 XR_006397787.1 0 0 18 0 0 NA NA NA NA NA NA 27400 XM_044307015.1 792 633 432 837 698 Q96M32 0 Adenylate kinase 7 (AK 7) (EC 2.7.4.3) (EC 2.7.4.6) (ATP-AMP transphosphorylase 7) Homo sapiens (Human) cell projection organization [GO:0030030]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142] GO:0004017; GO:0004127; GO:0004550; GO:0005524; GO:0005737; GO:0005829; GO:0006165; GO:0009142; GO:0030030; GO:0031514 27401 XM_044317723.1 36 0 19 204 110 NA NA NA NA NA NA 27402 XM_029337707.2 493 525 240 724 372 Q9GRC0 1.04e-71 Serine/threonine-protein kinase mos (EC 2.7.11.1) (Oocyte maturation factor mos) Patiria pectinifera (Starfish) (Asterina pectinifera) female gamete generation [GO:0007292]; female meiosis II [GO:0007147]; negative regulation of mitotic cell cycle [GO:0045930]; protein phosphorylation [GO:0006468] GO:0004709; GO:0005524; GO:0006468; GO:0007147; GO:0007292; GO:0045930; GO:0106310 27403 XM_044312078.1 10 0 2 5 21 Q9V5N8 1.46e-75 Protocadherin-like wing polarity protein stan (Protein flamingo) (Protein starry night) Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; axonogenesis [GO:0007409]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; dendrite development [GO:0016358]; dendrite morphogenesis [GO:0048813]; dendrite self-avoidance [GO:0070593]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; morphogenesis of a polarized epithelium [GO:0001738]; mushroom body development [GO:0016319]; ommatidial rotation [GO:0016318]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669]; R3/R4 development [GO:0048057]; regulation of axonogenesis [GO:0050770]; regulation of synapse assembly [GO:0051963]; regulation of tube length, open tracheal system [GO:0035159]; segment polarity determination [GO:0007367] GO:0001736; GO:0001737; GO:0001738; GO:0004888; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007156; GO:0007166; GO:0007367; GO:0007409; GO:0007411; GO:0016020; GO:0016318; GO:0016319; GO:0016324; GO:0016339; GO:0016358; GO:0035159; GO:0042067; GO:0045773; GO:0048057; GO:0048813; GO:0050770; GO:0050839; GO:0051963; GO:0070593; GO:0098609; GO:1902669 27404 XM_044312078.1 10 0 2 5 21 Q9V5N8 3.2e-62 Protocadherin-like wing polarity protein stan (Protein flamingo) (Protein starry night) Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; axonogenesis [GO:0007409]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; dendrite development [GO:0016358]; dendrite morphogenesis [GO:0048813]; dendrite self-avoidance [GO:0070593]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; morphogenesis of a polarized epithelium [GO:0001738]; mushroom body development [GO:0016319]; ommatidial rotation [GO:0016318]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669]; R3/R4 development [GO:0048057]; regulation of axonogenesis [GO:0050770]; regulation of synapse assembly [GO:0051963]; regulation of tube length, open tracheal system [GO:0035159]; segment polarity determination [GO:0007367] GO:0001736; GO:0001737; GO:0001738; GO:0004888; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007156; GO:0007166; GO:0007367; GO:0007409; GO:0007411; GO:0016020; GO:0016318; GO:0016319; GO:0016324; GO:0016339; GO:0016358; GO:0035159; GO:0042067; GO:0045773; GO:0048057; GO:0048813; GO:0050770; GO:0050839; GO:0051963; GO:0070593; GO:0098609; GO:1902669 27405 XM_044312078.1 10 0 2 5 21 Q9V5N8 1.47e-60 Protocadherin-like wing polarity protein stan (Protein flamingo) (Protein starry night) Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; axonogenesis [GO:0007409]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; dendrite development [GO:0016358]; dendrite morphogenesis [GO:0048813]; dendrite self-avoidance [GO:0070593]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; morphogenesis of a polarized epithelium [GO:0001738]; mushroom body development [GO:0016319]; ommatidial rotation [GO:0016318]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669]; R3/R4 development [GO:0048057]; regulation of axonogenesis [GO:0050770]; regulation of synapse assembly [GO:0051963]; regulation of tube length, open tracheal system [GO:0035159]; segment polarity determination [GO:0007367] GO:0001736; GO:0001737; GO:0001738; GO:0004888; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007156; GO:0007166; GO:0007367; GO:0007409; GO:0007411; GO:0016020; GO:0016318; GO:0016319; GO:0016324; GO:0016339; GO:0016358; GO:0035159; GO:0042067; GO:0045773; GO:0048057; GO:0048813; GO:0050770; GO:0050839; GO:0051963; GO:0070593; GO:0098609; GO:1902669 27406 XM_044312078.1 10 0 2 5 21 Q9V5N8 6.2e-58 Protocadherin-like wing polarity protein stan (Protein flamingo) (Protein starry night) Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; axonogenesis [GO:0007409]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; dendrite development [GO:0016358]; dendrite morphogenesis [GO:0048813]; dendrite self-avoidance [GO:0070593]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; morphogenesis of a polarized epithelium [GO:0001738]; mushroom body development [GO:0016319]; ommatidial rotation [GO:0016318]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669]; R3/R4 development [GO:0048057]; regulation of axonogenesis [GO:0050770]; regulation of synapse assembly [GO:0051963]; regulation of tube length, open tracheal system [GO:0035159]; segment polarity determination [GO:0007367] GO:0001736; GO:0001737; GO:0001738; GO:0004888; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007156; GO:0007166; GO:0007367; GO:0007409; GO:0007411; GO:0016020; GO:0016318; GO:0016319; GO:0016324; GO:0016339; GO:0016358; GO:0035159; GO:0042067; GO:0045773; GO:0048057; GO:0048813; GO:0050770; GO:0050839; GO:0051963; GO:0070593; GO:0098609; GO:1902669 27407 XM_044312078.1 10 0 2 5 21 Q9V5N8 5.5e-33 Protocadherin-like wing polarity protein stan (Protein flamingo) (Protein starry night) Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; axonogenesis [GO:0007409]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; dendrite development [GO:0016358]; dendrite morphogenesis [GO:0048813]; dendrite self-avoidance [GO:0070593]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; morphogenesis of a polarized epithelium [GO:0001738]; mushroom body development [GO:0016319]; ommatidial rotation [GO:0016318]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669]; R3/R4 development [GO:0048057]; regulation of axonogenesis [GO:0050770]; regulation of synapse assembly [GO:0051963]; regulation of tube length, open tracheal system [GO:0035159]; segment polarity determination [GO:0007367] GO:0001736; GO:0001737; GO:0001738; GO:0004888; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007156; GO:0007166; GO:0007367; GO:0007409; GO:0007411; GO:0016020; GO:0016318; GO:0016319; GO:0016324; GO:0016339; GO:0016358; GO:0035159; GO:0042067; GO:0045773; GO:0048057; GO:0048813; GO:0050770; GO:0050839; GO:0051963; GO:0070593; GO:0098609; GO:1902669 27408 XM_029344495.2 6780 6030 3607 6243 5387 P41932 1.03e-99 14-3-3-like protein 1 (Partitioning defective protein 5) Caenorhabditis elegans asymmetric protein localization involved in cell fate determination [GO:0045167]; cell fate specification [GO:0001708]; cytoplasmic sequestering of transcription factor [GO:0042994]; determination of adult lifespan [GO:0008340]; embryo development ending in birth or egg hatching [GO:0009792]; establishment of mitotic spindle orientation [GO:0000132]; first cell cycle pseudocleavage [GO:0030590]; heat acclimation [GO:0010286]; maintenance of protein location in nucleus [GO:0051457]; meiotic cell cycle [GO:0051321]; negative regulation of gene expression [GO:0010629]; polarity specification of anterior/posterior axis [GO:0009949]; pronuclear migration [GO:0035046]; protein export from nucleus [GO:0006611]; regulation of gene expression [GO:0010468]; regulation of mitotic cell cycle [GO:0007346]; reproduction [GO:0000003]; signal transduction [GO:0007165]; zygote asymmetric cell division [GO:0010070] GO:0000003; GO:0000132; GO:0001708; GO:0005634; GO:0005737; GO:0005938; GO:0006611; GO:0007165; GO:0007346; GO:0008340; GO:0009792; GO:0009949; GO:0010070; GO:0010286; GO:0010468; GO:0010629; GO:0030590; GO:0035046; GO:0042994; GO:0045167; GO:0051321; GO:0051457 27409 XM_029348150.2 164 86 81 161 232 Q6BEB4 1.57e-56 Transcription factor Sp5 Homo sapiens (Human) bone morphogenesis [GO:0060349]; cellular response to organic cyclic compound [GO:0071407]; post-anal tail morphogenesis [GO:0036342]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000785; GO:0000978; GO:0000981; GO:0001227; GO:0005634; GO:0006357; GO:0036342; GO:0046872; GO:0060349; GO:0071407 27410 XM_029356690.2 316 223 113 305 198 J3S9D9 9.42e-27 Reticulocalbin-2 (Taipoxin-associated calcium-binding protein 49 homolog) Crotalus adamanteus (Eastern diamondback rattlesnake) NA GO:0005509; GO:0005576 27411 XM_029356610.2 2 0 15 0 22 NA NA NA NA NA NA 27412 XM_044312975.1 56 18 9 0 36 Q8NBF2 0 NHL repeat-containing protein 2 Homo sapiens (Human) NA GO:0005576; GO:0005829; GO:0031093 27413 XM_029351101.2 0 29 0 10 0 NA NA NA NA NA NA 27414 XR_006398089.1 44 12 9 62 60 NA NA NA NA NA NA 27415 XM_029336606.2 403 416 308 281 155 NA NA NA NA NA NA 27416 XM_044309542.1 0 0 0 0 9 NA NA NA NA NA NA 27417 XM_029335095.2 1862 1101 744 1170 1134 Q9FPH3 3.38e-98 Probable low-specificity L-threonine aldolase 2 (EC 4.1.2.48) (Threonine aldolase 2) Arabidopsis thaliana (Mouse-ear cress) glycine biosynthetic process [GO:0006545]; threonine catabolic process [GO:0006567] GO:0004793; GO:0005829; GO:0006545; GO:0006567; GO:0008732 27418 XR_003825597.2 0 65 0 96 0 NA NA NA NA NA NA 27419 XM_044320577.1 0 0 66 0 65 NA NA NA NA NA NA 27420 XM_044323354.1 38 83 18 97 57 NA NA NA NA NA NA 27421 XM_044324854.1 299 21 37 40 1219 Q58A42 8.22e-74 Protein DD3-3 Dictyostelium discoideum (Social amoeba) NA GO:0016020 27422 XR_006397548.1 23 18 3 47 0 NA NA NA NA NA NA 27423 XM_044307708.1 18 18 0 42 118 NA NA NA NA NA NA 27424 XM_029357680.2 0 0 0 19 0 A1L1W9 7.26e-59 Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10) Danio rerio (Zebrafish) (Brachydanio rerio) aromatic amino acid transport [GO:0015801]; thyroid hormone transport [GO:0070327] GO:0005302; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0070327 27425 XM_044327980.1 174 33 43 67 136 NA NA NA NA NA NA 27426 XM_029352513.2 1 23 14 35 173 NA NA NA NA NA NA 27427 XM_029344203.2 126 60 61 55 127 Q4HX89 1.27e-46 Protein BTN1 Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1) (Wheat head blight fungus) (Fusarium graminearum) amino acid transport [GO:0006865] GO:0005774; GO:0006865 27428 XM_029343254.2 4185 3028 1703 2478 1974 Q8NDH3 0 Probable aminopeptidase NPEPL1 (EC 3.4.11.-) (Aminopeptidase-like 1) Homo sapiens (Human) proteolysis [GO:0006508] GO:0005634; GO:0005737; GO:0006508; GO:0008233; GO:0030145; GO:0070006 27429 XM_044319991.1 0 10 0 0 0 NA NA NA NA NA NA 27430 XM_044327769.1 26 0 10 2 2 NA NA NA NA NA NA 27431 XR_003826027.2 5 18 0 4 8 NA NA NA NA NA NA 27432 XM_044313499.1 0 3 0 49 80 NA NA NA NA NA NA 27433 XM_044313935.1 0 46 103 0 0 NA NA NA NA NA NA 27434 XM_029350700.2 15 0 0 12 0 F1P4W9 0 Cilia- and flagella-associated protein 65 (Coiled-coil domain-containing protein 108) Gallus gallus (Chicken) flagellated sperm motility [GO:0030317]; sperm axoneme assembly [GO:0007288] GO:0001669; GO:0002080; GO:0005737; GO:0005886; GO:0007288; GO:0030317; GO:0036126; GO:0097225 27435 XM_029331566.2 0 0 0 513 158 Q5RAM2 3.72e-58 Estrogen-related receptor gamma (Estrogen receptor-related protein 3) (Nuclear receptor subfamily 3 group B member 3) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) regulation of DNA-templated transcription [GO:0006355]; retinoic acid receptor signaling pathway [GO:0048384] GO:0003707; GO:0004879; GO:0005496; GO:0005654; GO:0006355; GO:0008270; GO:0043565; GO:0048384 27436 XM_044321936.1 5763 3178 3139 6525 6786 P15311 1.24e-155 Ezrin (Cytovillin) (Villin-2) (p81) Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; astral microtubule organization [GO:0030953]; cellular response to cAMP [GO:0071320]; cortical microtubule organization [GO:0043622]; establishment of centrosome localization [GO:0051660]; establishment of endothelial barrier [GO:0061028]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; filopodium assembly [GO:0046847]; intestinal D-glucose absorption [GO:0001951]; leukocyte cell-cell adhesion [GO:0007159]; membrane to membrane docking [GO:0022614]; microvillus assembly [GO:0030033]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of gene expression [GO:0010628]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein secretion [GO:0050714]; postsynaptic actin cytoskeleton organization [GO:0098974]; protein kinase A signaling [GO:0010737]; protein localization to cell cortex [GO:0072697]; protein localization to plasma membrane [GO:0072659]; protein-containing complex localization [GO:0031503]; receptor internalization [GO:0031623]; regulation of cell shape [GO:0008360]; regulation of microvillus length [GO:0032532]; regulation of organelle assembly [GO:1902115]; sphingosine-1-phosphate receptor signaling pathway [GO:0003376]; terminal web assembly [GO:1902896] GO:0000122; GO:0001650; GO:0001726; GO:0001772; GO:0001931; GO:0001951; GO:0003376; GO:0003723; GO:0003779; GO:0005615; GO:0005737; GO:0005768; GO:0005829; GO:0005884; GO:0005886; GO:0005902; GO:0005903; GO:0005912; GO:0005925; GO:0007159; GO:0008017; GO:0008022; GO:0008360; GO:0010628; GO:0010737; GO:0015629; GO:0016020; GO:0016323; GO:0016324; GO:0019898; GO:0019904; GO:0022614; GO:0030033; GO:0030175; GO:0030863; GO:0030953; GO:0031503; GO:0031528; GO:0031532; GO:0031623; GO:0031982; GO:0032532; GO:0032587; GO:0032703; GO:0032991; GO:0034236; GO:0034237; GO:0035088; GO:0036064; GO:0040018; GO:0042802; GO:0042995; GO:0043622; GO:0044548; GO:0044853; GO:0045177; GO:0045296; GO:0045732; GO:0046847; GO:0048015; GO:0048471; GO:0050714; GO:0050839; GO:0050860; GO:0051015; GO:0051017; GO:0051018; GO:0051117; GO:0051660; GO:0061028; GO:0070062; GO:0070373; GO:0071320; GO:0071944; GO:0072659; GO:0072697; GO:0097718; GO:0098592; GO:0098974; GO:1902115; GO:1902896; GO:1902966; GO:1903078; GO:1903753; GO:2000643 27437 XM_044325547.1 649 276 315 416 297 Q9NSN8 2.46e-80 Gamma-1-syntrophin (G1SYN) (Syntrophin-4) (SYN4) Homo sapiens (Human) cell communication [GO:0007154] GO:0003779; GO:0005198; GO:0005634; GO:0005737; GO:0005856; GO:0007154; GO:0008022; GO:0016010; GO:0016013; GO:0032587 27438 XM_044309963.1 116 113 57 90 77 NA NA NA NA NA NA 27439 XM_044318066.1 60 44 58 51 86 NA NA NA NA NA NA 27440 XM_029341683.2 0 0 78 0 97 P05132 0 cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11) Mus musculus (Mouse) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cellular response to cold [GO:0070417]; cellular response to glucose stimulus [GO:0071333]; cellular response to heat [GO:0034605]; cellular response to parathyroid hormone stimulus [GO:0071374]; mesoderm formation [GO:0001707]; modulation of chemical synaptic transmission [GO:0050804]; mRNA processing [GO:0006397]; negative regulation of meiotic cell cycle [GO:0051447]; negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:1901621]; neural tube closure [GO:0001843]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of insulin secretion [GO:0032024]; positive regulation of protein export from nucleus [GO:0046827]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; protein autophosphorylation [GO:0046777]; protein export from nucleus [GO:0006611]; protein kinase A signaling [GO:0010737]; protein localization to lipid droplet [GO:1990044]; protein phosphorylation [GO:0006468]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of cell cycle [GO:0051726]; regulation of cellular respiration [GO:0043457]; regulation of osteoblast differentiation [GO:0045667]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of protein processing [GO:0070613]; regulation of synaptic transmission, glutamatergic [GO:0051966]; sperm capacitation [GO:0048240]; spontaneous exocytosis of neurotransmitter [GO:0048792] GO:0000287; GO:0001669; GO:0001707; GO:0001843; GO:0004672; GO:0004674; GO:0004679; GO:0004691; GO:0004712; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005794; GO:0005813; GO:0005829; GO:0005886; GO:0005930; GO:0005952; GO:0006397; GO:0006468; GO:0006611; GO:0007189; GO:0008284; GO:0010737; GO:0016020; GO:0016607; GO:0018105; GO:0018107; GO:0019901; GO:0019904; GO:0030145; GO:0031267; GO:0031588; GO:0031594; GO:0031625; GO:0032024; GO:0032991; GO:0034237; GO:0034605; GO:0036126; GO:0043005; GO:0043197; GO:0043457; GO:0044853; GO:0044877; GO:0045667; GO:0046777; GO:0046827; GO:0048240; GO:0048471; GO:0048792; GO:0050804; GO:0051447; GO:0051726; GO:0051966; GO:0061136; GO:0070417; GO:0070613; GO:0071333; GO:0071374; GO:0097225; GO:0097546; GO:0098793; GO:0098794; GO:0098978; GO:0099170; GO:0106310; GO:1901621; GO:1990044; GO:2000810 27441 XM_044309089.1 498 287 192 525 741 Q8VEH8 1.31e-104 Endoplasmic reticulum lectin 1 (ER lectin) (Erlectin) Mus musculus (Mouse) endoplasmic reticulum unfolded protein response [GO:0030968]; negative regulation of retrograde protein transport, ER to cytosol [GO:1904153]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0005788; GO:0030433; GO:0030968; GO:0051082; GO:1904153 27442 XM_044317803.1 0 31 8 0 2 A0A0H2VDN9 9.23e-25 Secretory immunoglobulin A-binding protein EsiB Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) negative regulation of immune response [GO:0050777]; negative regulation of neutrophil activation [GO:1902564] GO:0009986; GO:0019862; GO:0046872; GO:0050777; GO:1902564 27443 XM_044317803.1 0 31 8 0 2 A0A0H2VDN9 9.41e-25 Secretory immunoglobulin A-binding protein EsiB Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) negative regulation of immune response [GO:0050777]; negative regulation of neutrophil activation [GO:1902564] GO:0009986; GO:0019862; GO:0046872; GO:0050777; GO:1902564 27444 XM_044317803.1 0 31 8 0 2 A0A0H2VDN9 2.71e-21 Secretory immunoglobulin A-binding protein EsiB Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) negative regulation of immune response [GO:0050777]; negative regulation of neutrophil activation [GO:1902564] GO:0009986; GO:0019862; GO:0046872; GO:0050777; GO:1902564 27445 XM_044306743.1 409 374 272 330 512 NA NA NA NA NA NA 27446 XM_044325690.1 84 10 52 22 195 NA NA NA NA NA NA 27447 XM_029330555.2 837 591 751 586 436 Q16595 4.28e-46 Frataxin, mitochondrial (EC 1.16.3.1) (Friedreich ataxia protein) (Fxn) [Cleaved into: Frataxin intermediate form (i-FXN); Frataxin(56-210) (m56-FXN); Frataxin(78-210) (d-FXN) (m78-FXN); Frataxin mature form (Frataxin(81-210)) (m81-FXN); Extramitochondrial frataxin] Homo sapiens (Human) [2Fe-2S] cluster assembly [GO:0044571]; [4Fe-4S] cluster assembly [GO:0044572]; adult walking behavior [GO:0007628]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; embryo development ending in birth or egg hatching [GO:0009792]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; mitochondrion organization [GO:0007005]; muscle cell cellular homeostasis [GO:0046716]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of organ growth [GO:0046621]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; organ growth [GO:0035265]; oxidative phosphorylation [GO:0006119]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]; proprioception [GO:0019230]; protein autoprocessing [GO:0016540]; regulation of ferrochelatase activity [GO:0010722]; response to iron ion [GO:0010039] GO:0004322; GO:0005739; GO:0005759; GO:0005829; GO:0006119; GO:0006783; GO:0006811; GO:0006879; GO:0007005; GO:0007628; GO:0008198; GO:0008199; GO:0008284; GO:0009792; GO:0010039; GO:0010722; GO:0016226; GO:0016540; GO:0018283; GO:0019230; GO:0030307; GO:0034986; GO:0035265; GO:0040015; GO:0043066; GO:0043085; GO:0044571; GO:0044572; GO:0046621; GO:0046716; GO:0051349; GO:0051537; GO:0070301; GO:0090201; GO:0099128; GO:1904231; GO:1904234; GO:1990221; GO:1990229 27448 XM_044314992.1 7 0 1 2 1 Q09575 4.21e-41 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 27449 XM_029352014.2 0 7 0 0 14 Q9CUX1 9.08e-35 52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (THAP domain-containing protein 0) (THAP domain-containing protein 12) Mus musculus (Mouse) NA GO:0003677; GO:0005634; GO:0046872; GO:0046983 27450 XM_044317278.1 26 3 19 0 114 NA NA NA NA NA NA 27451 XM_029350724.2 313 263 288 219 386 NA NA NA NA NA NA 27452 XM_029348952.2 654 398 337 498 496 O42182 1.34e-61 Fibulin-1 (FIBL-1) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic medial fin morphogenesis [GO:0035122]; extracellular matrix organization [GO:0030198]; mesenchymal cell migration [GO:0090497]; skin morphogenesis [GO:0043589] GO:0005509; GO:0005576; GO:0016504; GO:0030198; GO:0035122; GO:0043589; GO:0090497 27453 XM_029348952.2 654 398 337 498 496 O42182 5.96e-34 Fibulin-1 (FIBL-1) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic medial fin morphogenesis [GO:0035122]; extracellular matrix organization [GO:0030198]; mesenchymal cell migration [GO:0090497]; skin morphogenesis [GO:0043589] GO:0005509; GO:0005576; GO:0016504; GO:0030198; GO:0035122; GO:0043589; GO:0090497 27454 XR_006392712.1 157 53 130 150 270 NA NA NA NA NA NA 27455 XM_044312432.1 3 231 0 856 1 NA NA NA NA NA NA 27456 XM_029333213.2 35 9 39 44 49 NA NA NA NA NA NA 27457 XM_044317650.1 188 175 27 146 76 NA NA NA NA NA NA 27458 XM_029335345.2 1233 651 432 901 1103 Q9NRK6 0 ATP-binding cassette sub-family B member 10, mitochondrial (ABC-mitochondrial erythroid protein) (ABC-me protein) (ATP-binding cassette transporter 10) (ABC transporter 10 protein) (Mitochondrial ATP-binding cassette 2) (M-ABC2) Homo sapiens (Human) erythrocyte development [GO:0048821]; heme biosynthetic process [GO:0006783]; mitochondrial transport [GO:0006839]; mitochondrial unfolded protein response [GO:0034514]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of heme biosynthetic process [GO:0070455]; positive regulation of hemoglobin biosynthetic process [GO:0046985] GO:0005524; GO:0005739; GO:0005743; GO:0006783; GO:0006839; GO:0016887; GO:0031966; GO:0034514; GO:0042803; GO:0045648; GO:0046985; GO:0048821; GO:0070455; GO:0140359 27459 XM_029328813.1 1952 1063 993 751 257 Q497Q6 2.92e-22 Protein FAM228B Mus musculus (Mouse) NA NA 27460 XM_044314572.1 63 26 50 264 49 NA NA NA NA NA NA 27461 XM_029354793.2 3 92 125 25 193 NA NA NA NA NA NA 27462 XM_029327263.2 312 240 205 265 239 A4QNP7 1.99e-29 Doublesex- and mab-3-related transcription factor A2 (Doublesex- and mab-3-related transcription factor 5) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006355; GO:0043565; GO:0046872 27463 XM_044314681.1 1 0 0 0 12 P0CT39 6.21e-88 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 27464 XM_029345298.2 0 27 79 72 0 NA NA NA NA NA NA 27465 XR_006395070.1 1134 1497 672 1137 599 NA NA NA NA NA NA 27466 XM_044320990.1 0 131 48 0 0 O15050 0 TPR and ankyrin repeat-containing protein 1 (Lupus brain antigen 1 homolog) Homo sapiens (Human) NA NA 27467 XM_044307787.1 26 7 13 0 0 P47990 0 Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase) (XOR)] Gallus gallus (Chicken) urate biosynthetic process [GO:0034418]; xanthine catabolic process [GO:0009115] GO:0004854; GO:0004855; GO:0005506; GO:0005615; GO:0005777; GO:0005829; GO:0009115; GO:0016491; GO:0030151; GO:0034418; GO:0043546; GO:0050660; GO:0051537; GO:0070674; GO:0071949 27468 XM_044328150.1 0 0 0 147 0 P11362 1.92e-63 Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331) Homo sapiens (Human) cell migration [GO:0016477]; chordate embryonic development [GO:0043009]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; MAPK cascade [GO:0000165]; neuron migration [GO:0001764]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell differentiation [GO:0045595]; regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001239]; skeletal system development [GO:0001501]; skeletal system morphogenesis [GO:0048705]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0000165; GO:0001501; GO:0001764; GO:0001837; GO:0004713; GO:0004714; GO:0005007; GO:0005524; GO:0005576; GO:0005634; GO:0005829; GO:0005886; GO:0006468; GO:0007169; GO:0008201; GO:0008284; GO:0008543; GO:0010518; GO:0010863; GO:0014068; GO:0016020; GO:0016477; GO:0017134; GO:0018108; GO:0031410; GO:0033674; GO:0042802; GO:0042803; GO:0043009; GO:0043235; GO:0043406; GO:0043410; GO:0043536; GO:0045595; GO:0045597; GO:0045666; GO:0046777; GO:0048015; GO:0048705; GO:0051897; GO:0090722; GO:1905564; GO:2000546; GO:2001239 27469 XM_029348345.2 24 49 9 77 59 P49953 1.16e-26 Wilms tumor protein homolog Sminthopsis macroura (Stripe-faced dunnart) adrenal cortex formation [GO:0035802]; adrenal gland development [GO:0030325]; branching involved in ureteric bud morphogenesis [GO:0001658]; camera-type eye development [GO:0043010]; cellular response to gonadotropin stimulus [GO:0071371]; diaphragm development [GO:0060539]; epithelial cell differentiation [GO:0030855]; germ cell development [GO:0007281]; glomerulus development [GO:0032835]; gonad development [GO:0008406]; heart development [GO:0007507]; male genitalia development [GO:0030539]; mesenchymal to epithelial transition [GO:0060231]; metanephric mesenchyme development [GO:0072075]; metanephric S-shaped body morphogenesis [GO:0072284]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of female gonad development [GO:2000195]; negative regulation of metanephric glomerular mesangial cell proliferation [GO:0072302]; negative regulation of translation [GO:0017148]; podocyte differentiation [GO:0072112]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of heart growth [GO:0060421]; positive regulation of male gonad development [GO:2000020]; positive regulation of metanephric ureteric bud development [GO:2001076]; posterior mesonephric tubule development [GO:0072166]; regulation of animal organ formation [GO:0003156]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA splicing [GO:0008380]; sex determination [GO:0007530]; thorax and anterior abdomen determination [GO:0007356]; tissue development [GO:0009888]; ureteric bud development [GO:0001657]; vasculogenesis [GO:0001570]; visceral serous pericardium development [GO:0061032] GO:0000976; GO:0001228; GO:0001570; GO:0001657; GO:0001658; GO:0003156; GO:0003700; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006355; GO:0006357; GO:0007281; GO:0007356; GO:0007507; GO:0007530; GO:0008270; GO:0008380; GO:0008406; GO:0009888; GO:0010385; GO:0016607; GO:0017148; GO:0030308; GO:0030325; GO:0030539; GO:0030855; GO:0032835; GO:0035802; GO:0043010; GO:0043065; GO:0043066; GO:0043565; GO:0044729; GO:0045892; GO:0045893; GO:0060231; GO:0060421; GO:0060539; GO:0061032; GO:0071371; GO:0072075; GO:0072112; GO:0072166; GO:0072284; GO:0072302; GO:2000020; GO:2000195; GO:2001076 27470 XR_006395483.1 5 11 7 25 16 NA NA NA NA NA NA 27471 XM_029356649.2 3 4 9 0 1 NA NA NA NA NA NA 27472 XM_029342093.2 1833 1480 1517 1803 1583 Q9QX72 6.77e-62 Selenocysteine insertion sequence-binding protein 2 (SECIS-binding protein 2) Rattus norvegicus (Rat) forebrain neuron development [GO:0021884]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; neuron development [GO:0048666]; positive regulation of selenocysteine incorporation [GO:1904571]; selenocysteine incorporation [GO:0001514]; striatum development [GO:0021756] GO:0001514; GO:0003677; GO:0003723; GO:0003730; GO:0005634; GO:0005829; GO:0008135; GO:0021756; GO:0021884; GO:0035368; GO:0043021; GO:0048666; GO:1904571; GO:1990904; GO:2000623 27473 XM_029335778.2 7 0 6 7 25 NA NA NA NA NA NA 27474 XM_044322935.1 617 312 941 1102 930 Q8N0W4 2.1e-99 Neuroligin-4, X-linked (Neuroligin X) (HNLX) Homo sapiens (Human) adult behavior [GO:0030534]; brainstem development [GO:0003360]; cell-cell junction organization [GO:0045216]; cerebellum development [GO:0021549]; chemical synaptic transmission [GO:0007268]; learning [GO:0007612]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of excitatory postsynaptic potential [GO:0090394]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; organ growth [GO:0035265]; postsynaptic membrane assembly [GO:0097104]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; social behavior [GO:0035176]; synapse organization [GO:0050808]; synaptic vesicle endocytosis [GO:0048488]; vocalization behavior [GO:0071625] GO:0003360; GO:0005886; GO:0007158; GO:0007268; GO:0007612; GO:0009986; GO:0016020; GO:0021549; GO:0030182; GO:0030425; GO:0030534; GO:0031404; GO:0035176; GO:0035265; GO:0038023; GO:0042043; GO:0042803; GO:0045202; GO:0045216; GO:0048488; GO:0050804; GO:0050808; GO:0050839; GO:0060076; GO:0071625; GO:0090394; GO:0097104; GO:0097105; GO:0097110; GO:0098793; GO:0098839; GO:0098983; GO:0098985; GO:0099054; GO:0099634 27475 XM_044307060.1 22 24 55 27 48 Q8AV58 2.19e-55 Protein sidekick-1 Gallus gallus (Chicken) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; retina layer formation [GO:0010842]; synapse assembly [GO:0007416] GO:0005886; GO:0007156; GO:0007416; GO:0010842; GO:0042802; GO:0045202 27476 XM_044307060.1 22 24 55 27 48 Q8AV58 9.06e-37 Protein sidekick-1 Gallus gallus (Chicken) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; retina layer formation [GO:0010842]; synapse assembly [GO:0007416] GO:0005886; GO:0007156; GO:0007416; GO:0010842; GO:0042802; GO:0045202 27477 XM_044307060.1 22 24 55 27 48 Q8AV58 4.8e-31 Protein sidekick-1 Gallus gallus (Chicken) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; retina layer formation [GO:0010842]; synapse assembly [GO:0007416] GO:0005886; GO:0007156; GO:0007416; GO:0010842; GO:0042802; GO:0045202 27478 XM_029356064.2 152 31 48 41 190 Q8NB59 1.39e-31 Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV) Homo sapiens (Human) NA GO:0005543; GO:0016020 27479 XM_044324794.1 61 197 90 267 126 P35546 1.76e-81 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; anatomical structure morphogenesis [GO:0009653]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006919; GO:0007156; GO:0007158; GO:0007169; GO:0007399; GO:0009410; GO:0009653; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030182; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0098797; GO:2001241 27480 XM_029357479.2 274 208 190 247 299 P23228 0 Hydroxymethylglutaryl-CoA synthase, cytoplasmic (HMG-CoA synthase) (EC 2.3.3.10) (3-hydroxy-3-methylglutaryl coenzyme A synthase) Gallus gallus (Chicken) acetyl-CoA metabolic process [GO:0006084]; cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process, mevalonate pathway [GO:0010142] GO:0004421; GO:0005829; GO:0006084; GO:0006695; GO:0010142 27481 XM_029325387.2 0 8 0 22 4 A6H584 4.92e-26 Collagen alpha-5(VI) chain (Collagen alpha-1(XXIX) chain) Mus musculus (Mouse) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 27482 XR_006397709.1 363 109 50 158 221 NA NA NA NA NA NA 27483 XM_044313240.1 156 71 80 71 311 O95602 0 DNA-directed RNA polymerase I subunit RPA1 (RNA polymerase I subunit A1) (EC 2.7.7.6) (A190) (DNA-directed RNA polymerase I largest subunit) (DNA-directed RNA polymerase I subunit A) (RNA polymerase I 194 kDa subunit) (RPA194) Homo sapiens (Human) negative regulation of protein localization to nucleolus [GO:1904750] GO:0001054; GO:0003677; GO:0003682; GO:0005654; GO:0005694; GO:0005736; GO:0046872; GO:1904750 27484 XM_044313240.1 156 71 80 71 311 O95602 6.2e-48 DNA-directed RNA polymerase I subunit RPA1 (RNA polymerase I subunit A1) (EC 2.7.7.6) (A190) (DNA-directed RNA polymerase I largest subunit) (DNA-directed RNA polymerase I subunit A) (RNA polymerase I 194 kDa subunit) (RPA194) Homo sapiens (Human) negative regulation of protein localization to nucleolus [GO:1904750] GO:0001054; GO:0003677; GO:0003682; GO:0005654; GO:0005694; GO:0005736; GO:0046872; GO:1904750 27485 XM_044313621.1 130 17 13 81 54 Q6DCP1 1.12e-115 FAD-dependent oxidoreductase domain-containing protein 1 (EC 1.-.-.-) Xenopus laevis (African clawed frog) mitochondrial respiratory chain complex I assembly [GO:0032981] GO:0005743; GO:0005747; GO:0016491; GO:0032981 27486 XR_003824252.2 24 17 0 12 16 NA NA NA NA NA NA 27487 XM_029337999.2 546 345 334 605 422 P0DPD6 1.66e-142 Endothelin-converting enzyme 2 (ECE-2) (EC 3.4.24.71) Homo sapiens (Human) cell-cell signaling [GO:0007267]; G protein-coupled receptor signaling pathway [GO:0007186]; methylation [GO:0032259]; peptide hormone processing [GO:0016486]; protein processing [GO:0016485] GO:0000139; GO:0004222; GO:0005886; GO:0007186; GO:0007267; GO:0008168; GO:0016485; GO:0016486; GO:0030658; GO:0030659; GO:0032259; GO:0046872 27488 XM_044326401.1 1574 972 842 1572 1547 Q21086 1.75e-106 Guanine nucleotide-binding protein-like 3 homolog (Nucleostemin-1) Caenorhabditis elegans germ cell development [GO:0007281]; nematode larval development [GO:0002119]; regulation of cell population proliferation [GO:0042127]; regulation of multicellular organism growth [GO:0040014] GO:0002119; GO:0003924; GO:0005525; GO:0005634; GO:0005654; GO:0005730; GO:0007281; GO:0040014; GO:0042127 27489 XM_029356421.2 72 50 44 111 51 NA NA NA NA NA NA 27490 XM_044312762.1 27 38 26 26 164 NA NA NA NA NA NA 27491 XM_029348444.1 34 103 210 77 47 NA NA NA NA NA NA 27492 XR_006395527.1 116 0 74 9 164 NA NA NA NA NA NA 27493 XM_044310191.1 168 64 358 507 492 NA NA NA NA NA NA 27494 XM_044310267.1 68 31 14 62 42 Q640L5 2.59e-79 Coiled-coil domain-containing protein 18 Mus musculus (Mouse) NA GO:0005737; GO:0034451 27495 XM_029341885.2 2425 1672 1206 2366 2377 Q92541 1.26e-106 RNA polymerase-associated protein RTF1 homolog Homo sapiens (Human) blastocyst growth [GO:0001832]; endodermal cell fate commitment [GO:0001711]; histone H3-K4 trimethylation [GO:0080182]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of histone H3-K4 methylation [GO:0051571]; stem cell population maintenance [GO:0019827]; transcription elongation by RNA polymerase II promoter [GO:0006368]; Wnt signaling pathway [GO:0016055] GO:0000122; GO:0001711; GO:0001832; GO:0003697; GO:0003723; GO:0005654; GO:0005730; GO:0006368; GO:0016055; GO:0016593; GO:0019827; GO:0051571; GO:0080182; GO:1990269 27496 XM_044311456.1 19 0 39 7 133 NA NA NA NA NA NA 27497 XR_006391766.1 284 1307 135 739 3288 NA NA NA NA NA NA 27498 XM_044319193.1 65 2 7 7 14 NA NA NA NA NA NA 27499 XM_044317580.1 0 4 0 0 11 NA NA NA NA NA NA 27500 XR_006397081.1 0 0 0 0 20 NA NA NA NA NA NA 27501 XM_029342990.2 3863 1153 1506 3560 3150 Q9JID6 0 Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3) (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain acyl-CoA synthetase 1) (LACS 1) (Palmitoyl-CoA ligase) (Phytanate--CoA ligase) (EC 6.2.1.24) Cavia porcellus (Guinea pig) long-chain fatty acid metabolic process [GO:0001676]; very long-chain fatty acid metabolic process [GO:0000038] GO:0000038; GO:0001676; GO:0004467; GO:0005524; GO:0005741; GO:0005778; GO:0005783; GO:0005789; GO:0047676; GO:0050197; GO:0070251 27502 XM_044320074.1 0 46 0 9 0 Q3SX07 1.52e-28 tRNA pseudouridine(38/39) synthase (EC 5.4.99.45) (tRNA pseudouridine synthase 3) (tRNA pseudouridylate synthase 3) (tRNA-uridine isomerase 3) Bos taurus (Bovine) mRNA pseudouridine synthesis [GO:1990481]; tRNA pseudouridine synthesis [GO:0031119] GO:0003723; GO:0005634; GO:0005737; GO:0009982; GO:0031119; GO:0106029; GO:1990481 27503 XM_029352907.2 57 28 40 102 62 P97292 2.85e-28 Histamine H2 receptor (H2R) (HH2R) (Gastric receptor I) Mus musculus (Mouse) chemical synaptic transmission [GO:0007268]; digestive tract development [GO:0048565]; epithelial cell morphogenesis [GO:0003382]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; gastric acid secretion [GO:0001696]; gastrin-induced gastric acid secretion [GO:0001698]; gland development [GO:0048732]; histamine-induced gastric acid secretion [GO:0001697]; memory [GO:0007613]; negative regulation of arachidonic acid secretion [GO:1900139]; positive regulation of vasoconstriction [GO:0045907]; regulation of synaptic plasticity [GO:0048167]; toxin transport [GO:1901998]; visual learning [GO:0008542] GO:0001696; GO:0001697; GO:0001698; GO:0003382; GO:0004969; GO:0004993; GO:0005886; GO:0007187; GO:0007268; GO:0007613; GO:0008542; GO:0016020; GO:0030425; GO:0030594; GO:0045202; GO:0045907; GO:0048167; GO:0048565; GO:0048732; GO:1900139; GO:1901363; GO:1901998 27504 XR_006392601.1 3671 9237 2206 4201 3914 NA NA NA NA NA NA 27505 XM_029346094.2 46 832 1554 0 0 A8WJ42 2.56e-21 COA8 family protein CBG23705, mitochondrial (COA8) (APOPT family protein CBG23705, mitochondrial) Caenorhabditis briggsae intrinsic apoptotic signaling pathway [GO:0097193] GO:0005739; GO:0005743; GO:0097193 27506 XM_029341311.2 433 400 219 474 424 P74334 3.33e-65 Apocarotenoid-15,15'-oxygenase (ACO) (8'-apo-beta-carotenal 15,15'-oxygenase) (EC 1.13.11.75) (Diox1) Synechocystis sp. (strain PCC 6803 / Kazusa) carotene catabolic process [GO:0016121] GO:0010436; GO:0016121; GO:0046872; GO:0102162 27507 XR_006394091.1 7 15 0 27 0 NA NA NA NA NA NA 27508 XM_044319081.1 250 336 169 167 456 Q9QZ85 7.86e-51 Interferon-inducible GTPase 1 (EC 3.6.5.-) Mus musculus (Mouse) cellular response to interferon-beta [GO:0035458]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; regulation of autophagy [GO:0010506]; response to bacterium [GO:0009617] GO:0003924; GO:0005525; GO:0005737; GO:0005789; GO:0006952; GO:0009617; GO:0010506; GO:0019003; GO:0019221; GO:0020005; GO:0031965; GO:0032580; GO:0035458; GO:0042802; GO:0042832; GO:0045087; GO:0050829 27509 XM_029348695.2 1271 762 911 2328 2012 NA NA NA NA NA NA 27510 XM_029333319.2 133 15 0 9 142 Q12923 2.93e-57 Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1) (PTP-BAS) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (Protein-tyrosine phosphatase PTPL1) Homo sapiens (Human) cellular response to toxic substance [GO:0097237]; negative regulation of excitatory synapse assembly [GO:1904890]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066] GO:0001650; GO:0001933; GO:0004725; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0006470; GO:0014066; GO:0030027; GO:0035335; GO:0036312; GO:0043005; GO:0044297; GO:0070062; GO:0097237; GO:1904890 27511 XM_029333319.2 133 15 0 9 142 Q12923 1.97e-28 Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1) (PTP-BAS) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (Protein-tyrosine phosphatase PTPL1) Homo sapiens (Human) cellular response to toxic substance [GO:0097237]; negative regulation of excitatory synapse assembly [GO:1904890]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066] GO:0001650; GO:0001933; GO:0004725; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0006470; GO:0014066; GO:0030027; GO:0035335; GO:0036312; GO:0043005; GO:0044297; GO:0070062; GO:0097237; GO:1904890 27512 XM_029346819.2 191 560 301 509 0 Q8IV61 7.84e-135 Ras guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1) Homo sapiens (Human) MAPK cascade [GO:0000165]; positive regulation of GTPase activity [GO:0043547]; Ras protein signal transduction [GO:0007265]; small GTPase mediated signal transduction [GO:0007264] GO:0000165; GO:0005085; GO:0005096; GO:0005509; GO:0005886; GO:0007264; GO:0007265; GO:0019900; GO:0019992; GO:0031267; GO:0032045; GO:0043547; GO:0048471 27513 XM_044326043.1 22 1 29 0 35 P33450 1.59e-30 Cadherin-related tumor suppressor (Protein fat) [Cleaved into: Ft-mito] Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; equator specification [GO:0045317]; establishment of body hair planar orientation [GO:0048105]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; establishment or maintenance of polarity of larval imaginal disc epithelium [GO:0016336]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; imaginal disc-derived wing morphogenesis [GO:0007476]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of growth [GO:0045926]; negative regulation of imaginal disc growth [GO:0045571]; negative regulation of organ growth [GO:0046621]; positive regulation of apoptotic process [GO:0043065]; positive regulation of hippo signaling [GO:0035332]; protein localization involved in establishment of planar polarity [GO:0090251]; pupal development [GO:0035209]; regulation of establishment of planar polarity [GO:0090175]; regulation of growth [GO:0040008]; regulation of imaginal disc growth [GO:0045570]; regulation of protein localization [GO:0032880]; regulation of tube length, open tracheal system [GO:0035159]; tissue development [GO:0009888]; wing disc development [GO:0035220] GO:0001736; GO:0001737; GO:0005509; GO:0005739; GO:0005886; GO:0007156; GO:0007157; GO:0007164; GO:0007446; GO:0007447; GO:0007476; GO:0008285; GO:0009888; GO:0010629; GO:0016324; GO:0016327; GO:0016336; GO:0016339; GO:0032880; GO:0035159; GO:0035209; GO:0035220; GO:0035332; GO:0040008; GO:0042067; GO:0043065; GO:0044331; GO:0045296; GO:0045317; GO:0045570; GO:0045571; GO:0045926; GO:0046621; GO:0048105; GO:0090175; GO:0090176; GO:0090251; GO:0098609 27514 XM_029333165.2 814 583 433 589 434 B0WWP2 8.55e-100 Kelch-like protein diablo Culex quinquefasciatus (Southern house mosquito) (Culex pungens) negative regulation of synaptic assembly at neuromuscular junction [GO:0045886]; protein ubiquitination [GO:0016567] GO:0003779; GO:0016567; GO:0045886 27515 XM_044327374.1 50 3 70 6 216 NA NA NA NA NA NA 27516 XM_029324709.2 109 51 32 139 30 P48630 1.19e-114 Omega-6 fatty acid desaturase, endoplasmic reticulum isozyme 1 (EC 1.14.19.-) Glycine max (Soybean) (Glycine hispida) unsaturated fatty acid biosynthetic process [GO:0006636] GO:0005789; GO:0006636; GO:0016491 27517 XM_029357597.2 4844 7508 3037 3883 3993 Q52KD8 3.3e-44 Chromatin modification-related protein MEAF6 (MYST/Esa1-associated factor 6) (Esa1-associated factor 6 homolog) (Protein EAF6 homolog) Xenopus laevis (African clawed frog) chromatin organization [GO:0006325]; histone H2A acetylation [GO:0043968] GO:0000776; GO:0005730; GO:0006325; GO:0035267; GO:0043968; GO:0070776 27518 XM_044323234.1 0 0 0 63 180 Q9UNS1 1.24e-175 Protein timeless homolog (hTIM) Homo sapiens (Human) branching morphogenesis of an epithelial tube [GO:0048754]; cell cycle phase transition [GO:0044770]; cell division [GO:0051301]; cellular response to bleomycin [GO:1904976]; cellular response to cisplatin [GO:0072719]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hydroxyurea [GO:0072711]; circadian rhythm [GO:0007623]; detection of abiotic stimulus [GO:0009582]; DNA repair [GO:0006281]; DNA replication checkpoint signaling [GO:0000076]; lung development [GO:0030324]; morphogenesis of an epithelium [GO:0002009]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; regulation of circadian rhythm [GO:0042752]; replication fork arrest [GO:0043111]; replication fork protection [GO:0048478] GO:0000076; GO:0000785; GO:0002009; GO:0003677; GO:0005634; GO:0005654; GO:0006281; GO:0006974; GO:0007623; GO:0009582; GO:0030324; GO:0031298; GO:0035861; GO:0042752; GO:0042802; GO:0043111; GO:0044770; GO:0045892; GO:0048478; GO:0048754; GO:0051301; GO:0072711; GO:0072719; GO:1904976; GO:1905168; GO:2000781 27519 XM_044325366.1 494 192 216 243 269 O15439 0 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 27520 XM_044323811.1 7 0 13 5 33 NA NA NA NA NA NA 27521 XR_003827332.2 5 2 10 3 13 NA NA NA NA NA NA 27522 XR_006397990.1 80 41 0 154 73 NA NA NA NA NA NA 27523 XM_044309644.1 533 172 490 450 1039 Q9Z2W0 1.08e-179 Aspartyl aminopeptidase (EC 3.4.11.21) Mus musculus (Mouse) proteolysis [GO:0006508] GO:0004177; GO:0005829; GO:0006508; GO:0008237; GO:0008270; GO:0042802 27524 XM_044325220.1 23 28 37 0 41 P47972 2.46e-23 Neuronal pentraxin-2 (NP2) (Neuronal pentraxin II) (NP-II) Homo sapiens (Human) associative learning [GO:0008306]; chemical synaptic transmission [GO:0007268]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962] GO:0005576; GO:0007268; GO:0008306; GO:0030246; GO:0046872; GO:0098962; GO:0098978 27525 XM_044326141.1 0 0 0 16 0 NA NA NA NA NA NA 27526 XM_044325126.1 452 267 150 3 649 B3EX02 6.38e-124 MAM and fibronectin type III domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 27527 XM_044325126.1 452 267 150 3 649 B3EX02 3.01e-119 MAM and fibronectin type III domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 27528 XM_044325126.1 452 267 150 3 649 B3EX02 2.89e-112 MAM and fibronectin type III domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 27529 XM_044325126.1 452 267 150 3 649 B3EX02 1.34e-23 MAM and fibronectin type III domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 27530 XM_029332839.2 141 122 86 121 142 Q16281 1.47e-122 Cyclic nucleotide-gated cation channel alpha-3 (Cone photoreceptor cGMP-gated channel subunit alpha) (Cyclic nucleotide-gated channel alpha-3) (CNG channel alpha-3) (CNG-3) (CNG3) Homo sapiens (Human) cation transmembrane transport [GO:0098655]; cation transport [GO:0006812]; inorganic cation import across plasma membrane [GO:0098659]; response to cAMP [GO:0051591]; response to corticosteroid [GO:0031960]; response to magnesium ion [GO:0032026]; signal transduction [GO:0007165]; visual perception [GO:0007601] GO:0005222; GO:0005223; GO:0005737; GO:0005886; GO:0006812; GO:0007165; GO:0007601; GO:0008022; GO:0015276; GO:0017071; GO:0030425; GO:0030553; GO:0031960; GO:0032026; GO:0043194; GO:0043204; GO:0044877; GO:0051591; GO:0097386; GO:0098655; GO:0098659; GO:1902495 27531 XM_029358546.2 5441 7263 5678 5270 2683 NA NA NA NA NA NA 27532 XM_029357492.2 1093 630 432 752 859 Q9Z2D1 0 Myotubularin-related protein 2 (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64) Mus musculus (Mouse) dendritic spine maintenance [GO:0097062]; dephosphorylation [GO:0016311]; inositol phosphate dephosphorylation [GO:0046855]; myelin assembly [GO:0032288]; myelination [GO:0042552]; negative regulation of endocytosis [GO:0045806]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of myelination [GO:0031642]; negative regulation of receptor catabolic process [GO:2000645]; negative regulation of receptor internalization [GO:0002091]; neuron development [GO:0048666]; phosphatidylinositol dephosphorylation [GO:0046856]; phosphatidylinositol metabolic process [GO:0046488]; positive regulation of early endosome to late endosome transport [GO:2000643]; regulation of phosphatidylinositol dephosphorylation [GO:0060304] GO:0002091; GO:0004438; GO:0005634; GO:0005737; GO:0005774; GO:0005829; GO:0008021; GO:0014069; GO:0016311; GO:0030424; GO:0030425; GO:0031642; GO:0031901; GO:0032288; GO:0042552; GO:0042802; GO:0043197; GO:0043231; GO:0045806; GO:0046488; GO:0046855; GO:0046856; GO:0048471; GO:0048666; GO:0052629; GO:0052866; GO:0060304; GO:0090394; GO:0097060; GO:0097062; GO:2000643; GO:2000645 27533 XM_044317005.1 0 0 91 317 387 Q29RT6 2.15e-109 Kinesin-like protein KIF20A Bos taurus (Bovine) microtubule bundle formation [GO:0001578]; microtubule-based movement [GO:0007018]; midbody abscission [GO:0061952]; mitotic cytokinesis [GO:0000281]; protein transport [GO:0015031]; regulation of cytokinesis [GO:0032465] GO:0000281; GO:0001578; GO:0003777; GO:0005524; GO:0005634; GO:0005654; GO:0005794; GO:0005819; GO:0005871; GO:0005874; GO:0007018; GO:0008017; GO:0015031; GO:0016887; GO:0019901; GO:0030496; GO:0032465; GO:0045171; GO:0061952 27534 XR_006396831.1 0 0 10 0 0 NA NA NA NA NA NA 27535 XR_006395850.1 0 11 15 0 24 NA NA NA NA NA NA 27536 XM_029325339.2 449 371 212 534 347 Q504A5 6.71e-25 Probable thiopurine S-methyltransferase (Thiopurine methyltransferase) (EC 2.1.1.67) Danio rerio (Zebrafish) (Brachydanio rerio) methylation [GO:0032259] GO:0005737; GO:0008119; GO:0032259 27537 XM_044314608.1 11 3 10 0 0 Q96RW7 2.48e-101 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 27538 XM_044314608.1 11 3 10 0 0 Q96RW7 9.53e-90 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 27539 XM_044314608.1 11 3 10 0 0 Q96RW7 6.06e-87 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 27540 XM_044314608.1 11 3 10 0 0 Q96RW7 1.07e-86 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 27541 XM_044314608.1 11 3 10 0 0 Q96RW7 1.29e-86 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 27542 XM_044314608.1 11 3 10 0 0 Q96RW7 1.73e-86 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 27543 XM_044314608.1 11 3 10 0 0 Q96RW7 9.94e-85 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 27544 XM_044314608.1 11 3 10 0 0 Q96RW7 1.43e-82 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 27545 XM_044314608.1 11 3 10 0 0 Q96RW7 3.76e-70 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 27546 XM_044314608.1 11 3 10 0 0 Q96RW7 1.1e-67 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 27547 XM_029341351.2 59 63 37 47 64 NA NA NA NA NA NA 27548 XR_003827558.2 38 56 25 45 80 NA NA NA NA NA NA 27549 XM_044311948.1 0 9 0 10 3 NA NA NA NA NA NA 27550 XM_029356304.2 1050 2214 1776 451 8966 L5KLU7 8.54e-47 NA NA NA NA 27551 XR_003828597.2 9699 15299 4702 10781 5584 NA NA NA NA NA NA 27552 XM_044311440.1 2 0 0 0 7 NA NA NA NA NA NA 27553 XM_044313702.1 0 0 4 8 2 NA NA NA NA NA NA 27554 XM_029345072.2 55 37 49 73 63 NA NA NA NA NA NA 27555 XM_029346601.2 160 82 65 28 56 NA NA NA NA NA NA 27556 XM_029335227.2 1320 955 191 1185 234 Q6GM82 0 Alanine aminotransferase 2 (ALT2) (EC 2.6.1.2) (Glutamate pyruvate transaminase 2) (GPT 2) (Glutamic--alanine transaminase 2) (Glutamic--pyruvic transaminase 2) Xenopus laevis (African clawed frog) 2-oxoglutarate metabolic process [GO:0006103]; biosynthetic process [GO:0009058]; L-alanine catabolic process [GO:0042853]; L-alanine metabolic process [GO:0042851] GO:0004021; GO:0006103; GO:0009058; GO:0030170; GO:0042851; GO:0042853 27557 XM_029340413.2 15 7 7 0 18 Q9D4I2 9.01e-38 Meiosis inhibitor protein 1 (Meiosis defective protein 1) Mus musculus (Mouse) gamete generation [GO:0007276]; male meiosis I [GO:0007141]; meiosis I [GO:0007127]; meiotic cell cycle [GO:0051321]; meiotic spindle organization [GO:0000212]; meiotic telomere clustering [GO:0045141]; oogenesis [GO:0048477]; polar body extrusion after meiotic divisions [GO:0040038]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283] GO:0000212; GO:0007127; GO:0007141; GO:0007276; GO:0007283; GO:0007286; GO:0040038; GO:0045141; GO:0048477; GO:0051321 27558 XM_029350052.2 1223 718 572 788 906 Q9D9B4 6.52e-48 Leucine-rich melanocyte differentiation-associated protein Mus musculus (Mouse) melanocyte differentiation [GO:0030318] GO:0030318 27559 XM_044326347.1 3337 3254 3461 2556 303 R1CW23 2.95e-109 Dimethylsulfonioproprionate lyase 7 (DMSP lyase 7) (EC 4.4.1.3) (Dimethylpropiothetin dethiomethylase 7) Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi) NA GO:0047869 27560 XM_029358460.2 0 0 0 97 0 P54131 3.05e-66 Neuronal acetylcholine receptor subunit alpha-7 Bos taurus (Bovine) calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; cognition [GO:0050890]; ion transmembrane transport [GO:0034220]; negative regulation of tumor necrosis factor production [GO:0032720]; nervous system process [GO:0050877]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAPK cascade [GO:0043410]; regulation of membrane potential [GO:0042391]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271] GO:0001540; GO:0001666; GO:0005231; GO:0005886; GO:0005892; GO:0006816; GO:0006874; GO:0007165; GO:0007268; GO:0007271; GO:0008284; GO:0015464; GO:0015643; GO:0017081; GO:0022848; GO:0030594; GO:0032720; GO:0034220; GO:0035094; GO:0042166; GO:0042391; GO:0042803; GO:0043005; GO:0043410; GO:0045202; GO:0045211; GO:0045766; GO:0050877; GO:0050890; GO:1904315 27561 XM_029353909.2 79 36 69 8 181 NA NA NA NA NA NA 27562 XM_029330479.2 1144 725 576 862 761 Q9UGJ1 0 Gamma-tubulin complex component 4 (GCP-4) (hGCP4) (Gamma-ring complex protein 76 kDa) (h76p) (hGrip76) Homo sapiens (Human) cytoplasmic microtubule organization [GO:0031122]; meiotic cell cycle [GO:0051321]; microtubule nucleation [GO:0007020]; mitotic cell cycle [GO:0000278]; protein-containing complex assembly [GO:0065003]; spindle assembly [GO:0051225] GO:0000278; GO:0000922; GO:0000923; GO:0000930; GO:0000931; GO:0005200; GO:0005813; GO:0005829; GO:0005874; GO:0007020; GO:0015630; GO:0016020; GO:0031122; GO:0043015; GO:0051225; GO:0051321; GO:0055037; GO:0065003 27563 XM_029332673.2 768 1007 453 806 717 A1A5Q4 0 Cilia- and flagella-associated protein 206 Rattus norvegicus (Rat) axoneme assembly [GO:0035082]; cilium movement [GO:0003341]; regulation of cilium beat frequency [GO:0003356]; regulation of flagellated sperm motility [GO:1901317]; sperm axoneme assembly [GO:0007288] GO:0001534; GO:0003341; GO:0003356; GO:0005930; GO:0007288; GO:0031514; GO:0035082; GO:0036064; GO:1901317 27564 XM_029355775.2 829 445 426 643 776 Q6AX60 0 Protein PTHB1 (Bardet-Biedl syndrome 9 protein homolog) (Parathyroid hormone-responsive B1 gene protein homolog) Xenopus laevis (African clawed frog) NA GO:0005737; GO:0005815; GO:0005929; GO:0034464; GO:0060170 27565 XR_006397328.1 94 0 0 0 0 NA NA NA NA NA NA 27566 XR_003827509.1 3 34 25 31 10 NA NA NA NA NA NA 27567 XM_029338115.2 134 0 0 77 131 Q9GLK0 1.02e-162 Protein-glutamine gamma-glutamyltransferase K (EC 2.3.2.13) (Epidermal TGase) (Transglutaminase K) (TG(K)) (TGK) (TGase K) (Transglutaminase-1) (TGase-1) Canis lupus familiaris (Dog) (Canis familiaris) keratinization [GO:0031424]; peptide cross-linking [GO:0018149]; positive regulation of cell cycle [GO:0045787]; positive regulation of keratinocyte proliferation [GO:0010838] GO:0003810; GO:0010838; GO:0016020; GO:0018149; GO:0031424; GO:0045787; GO:0046872 27568 XM_044312500.1 1081 1228 985 681 1477 P97864 8.55e-52 Caspase-7 (CASP-7) (EC 3.4.22.60) (Apoptotic protease Mch-3) (Cysteine protease LICE2) [Cleaved into: Caspase-7 subunit p20; Caspase-7 subunit p11] Mus musculus (Mouse) apoptotic process [GO:0006915]; cellular response to staurosporine [GO:0072734]; defense response to bacterium [GO:0042742]; execution phase of apoptosis [GO:0097194]; extrinsic apoptotic signaling pathway [GO:0097191]; fibroblast apoptotic process [GO:0044346]; heart development [GO:0007507]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway [GO:0097193]; lymphocyte apoptotic process [GO:0070227]; neuron apoptotic process [GO:0051402]; positive regulation of apoptotic process [GO:0043065]; positive regulation of plasma membrane repair [GO:1905686]; protein catabolic process [GO:0030163]; protein processing [GO:0016485]; proteolysis [GO:0006508]; response to UV [GO:0009411] GO:0003723; GO:0004190; GO:0004197; GO:0005615; GO:0005634; GO:0005737; GO:0005829; GO:0006508; GO:0006915; GO:0006954; GO:0007507; GO:0008233; GO:0008234; GO:0008303; GO:0009411; GO:0016485; GO:0030163; GO:0035556; GO:0042742; GO:0043065; GO:0043231; GO:0044346; GO:0051402; GO:0070227; GO:0072734; GO:0097153; GO:0097191; GO:0097193; GO:0097194; GO:0097200; GO:1905686 27569 XM_044307893.1 35 2 10 11 15 Q09575 2.44e-61 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 27570 XR_006392967.1 41 2 25 5 151 NA NA NA NA NA NA 27571 XM_044315753.1 0 0 2 2 19 NA NA NA NA NA NA 27572 XR_006396641.1 37 53 39 49 11 NA NA NA NA NA NA 27573 XM_044329125.1 50 24 89 162 89 NA NA NA NA NA NA 27574 XM_029332901.2 546 376 287 437 310 NA NA NA NA NA NA 27575 XM_029332375.2 6326 3538 5287 6909 3540 Q0P8I7 3.65e-77 GDP-D-glycero-alpha-D-manno-heptose dehydrogenase (EC 1.1.98.-) Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) capsule polysaccharide biosynthetic process [GO:0045227]; protein homotetramerization [GO:0051289] GO:0003978; GO:0016491; GO:0019003; GO:0042802; GO:0045227; GO:0051289; GO:0070404 27576 XM_044318761.1 420 349 29 242 84 Q766D5 5.21e-57 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Mus musculus (Mouse) chondroitin sulfate biosynthetic process [GO:0030206] GO:0008376; GO:0030206; GO:0032580; GO:0033842; GO:0047238 27577 XM_044318761.1 420 349 29 242 84 Q766D5 3.85e-25 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Mus musculus (Mouse) chondroitin sulfate biosynthetic process [GO:0030206] GO:0008376; GO:0030206; GO:0032580; GO:0033842; GO:0047238 27578 XM_029332363.2 1196 577 281 582 542 Q9V4P1 7.13e-61 Anillin (Actin-binding protein 8) (ABP8) (Protein scraps) Drosophila melanogaster (Fruit fly) actomyosin contractile ring assembly [GO:0000915]; asymmetric cell division [GO:0008356]; cellularization [GO:0007349]; establishment of actomyosin contractile ring localization [GO:0032188]; intercellular bridge organization [GO:0043063]; male germline ring canal formation [GO:0030726]; male meiosis cytokinesis [GO:0007112]; mitotic cytokinesis [GO:0000281]; oogenesis [GO:0048477]; plasma membrane organization [GO:0007009]; pole cell formation [GO:0007279]; protein localization [GO:0008104]; regulation of cytokinesis [GO:0032465]; sensory organ development [GO:0007423]; sensory organ precursor cell division [GO:0045035]; septin ring organization [GO:0031106] GO:0000281; GO:0000915; GO:0003779; GO:0005634; GO:0005737; GO:0005826; GO:0007009; GO:0007112; GO:0007279; GO:0007349; GO:0007423; GO:0008017; GO:0008104; GO:0008356; GO:0017022; GO:0030726; GO:0031106; GO:0032154; GO:0032188; GO:0032465; GO:0035323; GO:0043063; GO:0045035; GO:0045172; GO:0048477; GO:0051015; GO:0070938 27579 XM_044310087.1 0 0 0 0 10 P34410 2.96e-24 TWiK family of potassium channels protein 7 Caenorhabditis elegans potassium ion transmembrane transport [GO:0071805]; stabilization of membrane potential [GO:0030322] GO:0005886; GO:0015271; GO:0022841; GO:0030322; GO:0071805 27580 XM_029346524.2 0 0 0 0 75 Q9I8C7 1.03e-92 Neuronal acetylcholine receptor subunit alpha-10 (Alpha 10 nAChR) (Nicotinic acetylcholine receptor subunit alpha-10) (NACHR alpha-10) Gallus gallus (Chicken) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; response to auditory stimulus [GO:0010996]; signal transduction [GO:0007165] GO:0004888; GO:0005231; GO:0005262; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0010996; GO:0022848; GO:0030594; GO:0034220; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051899; GO:1904315 27581 XM_044324024.1 713 810 380 694 555 A2CI35 4.26e-24 Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein kinase) (Dusty PK) (Receptor-interacting serine/threonine-protein kinase 5) Strongylocentrotus purpuratus (Purple sea urchin) cellular response to fibroblast growth factor stimulus [GO:0044344]; embryonic organ development [GO:0048568]; negative regulation of apoptotic process [GO:0043066]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast growth factor receptor signaling pathway [GO:0045743] GO:0004674; GO:0004712; GO:0004713; GO:0005524; GO:0005737; GO:0016323; GO:0016324; GO:0043066; GO:0044344; GO:0045743; GO:0048568; GO:0070161; GO:0070374; GO:0106310 27582 XM_029338123.2 0 329 154 768 251 P08510 7.65e-88 Potassium voltage-gated channel protein Shaker (Protein minisleep) Drosophila melanogaster (Fruit fly) action potential [GO:0001508]; axon extension [GO:0048675]; behavioral response to ether [GO:0048150]; cellular response to dopamine [GO:1903351]; courtship behavior [GO:0007619]; detection of visible light [GO:0009584]; larval locomotory behavior [GO:0008345]; learning or memory [GO:0007611]; mating behavior, sex discrimination [GO:0048047]; positive regulation of circadian sleep/wake cycle, sleep [GO:0045938]; positive regulation of membrane potential [GO:0045838]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; proboscis extension reflex [GO:0007637]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; regulation of ion transmembrane transport [GO:0034765]; regulation of synaptic activity [GO:0060025]; sensory perception of taste [GO:0050909]; sleep [GO:0030431] GO:0001508; GO:0005249; GO:0005251; GO:0006813; GO:0007611; GO:0007619; GO:0007637; GO:0008076; GO:0008345; GO:0009584; GO:0016020; GO:0022843; GO:0030431; GO:0034765; GO:0045187; GO:0045838; GO:0045938; GO:0048047; GO:0048150; GO:0048675; GO:0050909; GO:0051260; GO:0060025; GO:0071805; GO:1903351 27583 XR_006396769.1 148 226 169 168 199 NA NA NA NA NA NA 27584 XM_044322005.1 0 17 14 1 25 Q5ZIJ0 2.92e-35 BUD13 homolog Gallus gallus (Chicken) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0005634; GO:0005684; GO:0070274; GO:0071005 27585 XM_044318130.1 82 15 1 65 7 NA NA NA NA NA NA 27586 XM_029336430.2 946 587 347 813 590 Q5ZHN3 0 WD repeat domain phosphoinositide-interacting protein 2 (WIPI-2) Gallus gallus (Chicken) autophagosome assembly [GO:0000045]; autophagy of mitochondrion [GO:0000422]; autophagy of nucleus [GO:0044804]; cellular response to starvation [GO:0009267]; protein lipidation [GO:0006497]; protein localization to phagophore assembly site [GO:0034497] GO:0000045; GO:0000422; GO:0005829; GO:0006497; GO:0009267; GO:0019898; GO:0032266; GO:0034045; GO:0034497; GO:0044804; GO:0080025 27587 XM_029357155.2 387 131 165 324 522 Q8K0V4 6.64e-97 CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3) Mus musculus (Mouse) negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; positive regulation of cold-induced thermogenesis [GO:0120162]; regulation of DNA-templated transcription [GO:0006355]; regulation of stem cell population maintenance [GO:2000036]; RNA-mediated gene silencing [GO:0031047]; trophectodermal cell differentiation [GO:0001829] GO:0000289; GO:0000932; GO:0001829; GO:0005634; GO:0006355; GO:0030014; GO:0030015; GO:0031047; GO:0033147; GO:0120162; GO:2000036 27588 XM_029357155.2 387 131 165 324 522 Q8K0V4 1.9e-72 CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3) Mus musculus (Mouse) negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; positive regulation of cold-induced thermogenesis [GO:0120162]; regulation of DNA-templated transcription [GO:0006355]; regulation of stem cell population maintenance [GO:2000036]; RNA-mediated gene silencing [GO:0031047]; trophectodermal cell differentiation [GO:0001829] GO:0000289; GO:0000932; GO:0001829; GO:0005634; GO:0006355; GO:0030014; GO:0030015; GO:0031047; GO:0033147; GO:0120162; GO:2000036 27589 XR_006394620.1 180 62 144 106 121 NA NA NA NA NA NA 27590 XM_029337568.2 24 2 20 11 3 NA NA NA NA NA NA 27591 XM_029340636.2 2174 868 750 1328 870 Q5R4Q8 7.96e-50 Protein prune homolog 2 (BNIP2 motif-containing molecule at the C-terminal region 1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) apoptotic process [GO:0006915] GO:0005737; GO:0006915 27592 XM_044317649.1 2 0 0 7 12 NA NA NA NA NA NA 27593 XR_003824551.2 17 13 5 11 10 NA NA NA NA NA NA 27594 XM_044323577.1 84 89 8 96 29 NA NA NA NA NA NA 27595 XM_029348655.2 29 21 1 50 133 C3ZQF9 1.9e-25 QRFP-like peptide receptor Branchiostoma floridae (Florida lancelet) (Amphioxus) cellular response to peptide [GO:1901653]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:1901653 27596 XR_003825241.2 55 68 0 58 0 NA NA NA NA NA NA 27597 XR_006391905.1 241 166 66 93 66 NA NA NA NA NA NA 27598 XM_029328381.2 543 3471 2512 3883 1906 NA NA NA NA NA NA 27599 XR_006393141.1 609 601 615 162 430 NA NA NA NA NA NA 27600 XM_044311820.1 14 10 0 0 13 Q9VBW3 1.46e-58 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 27601 XM_029337619.2 312 230 272 174 347 A5PJU6 1.87e-43 Hydroxylysine kinase (5-hydroxy-L-lysine kinase) (EC 2.7.1.81) (Aminoglycoside phosphotransferase domain-containing protein 1) Bos taurus (Bovine) phosphorylation [GO:0016310] GO:0005737; GO:0016310; GO:0019202; GO:0047992 27602 XR_006395547.1 189 111 160 146 174 Q06S87 9.13e-34 5-hydroxyisourate hydrolase (HIU hydrolase) (HIUHase) (EC 3.5.2.17) (Transthyretin-related protein) Danio rerio (Zebrafish) (Brachydanio rerio) purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628] GO:0005777; GO:0006144; GO:0016811; GO:0019628; GO:0033971 27603 XM_044311730.1 65 48 27 89 66 NA NA NA NA NA NA 27604 XR_006391953.1 302 107 132 265 436 NA NA NA NA NA NA 27605 XM_044319629.1 1 0 14 37 11 NA NA NA NA NA NA 27606 XM_044316272.1 4 19 8 0 2 NA NA NA NA NA NA 27607 XM_029336193.2 2117 1576 868 1884 1267 NA NA NA NA NA NA 27608 XM_044311076.1 110 57 40 43 4 NA NA NA NA NA NA 27609 XM_044309418.1 26 0 0 2 11 NA NA NA NA NA NA 27610 XM_044323378.1 31 40 12 70 53 NA NA NA NA NA NA 27611 XM_044308484.1 1 0 23 47 25 NA NA NA NA NA NA 27612 XM_044320159.1 363 642 243 184 52 Q6DG99 5.53e-22 BTB/POZ domain-containing protein KCTD6 Danio rerio (Zebrafish) (Brachydanio rerio) protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567] GO:0016567; GO:0051260 27613 XR_003825314.2 312 194 176 196 159 NA NA NA NA NA NA 27614 XR_006395662.1 0 0 6 5 1 NA NA NA NA NA NA 27615 XR_006397955.1 0 0 0 0 7 NA NA NA NA NA NA 27616 XM_029346491.2 0 0 16 45 47 Q9UKP4 0 A disintegrin and metalloproteinase with thrombospondin motifs 7 (ADAM-TS 7) (ADAM-TS7) (ADAMTS-7) (EC 3.4.24.-) (COMPase) Homo sapiens (Human) cellular response to BMP stimulus [GO:0071773]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; chondrocyte differentiation [GO:0002062]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; negative regulation of chondrocyte differentiation [GO:0032331]; ossification involved in bone maturation [GO:0043931]; proteoglycan metabolic process [GO:0006029]; proteolysis involved in protein catabolic process [GO:0051603] GO:0002062; GO:0004222; GO:0005576; GO:0005788; GO:0006029; GO:0008237; GO:0009986; GO:0030198; GO:0030199; GO:0031012; GO:0032331; GO:0043931; GO:0046872; GO:0051603; GO:0071347; GO:0071356; GO:0071773 27617 XM_029346491.2 0 0 16 45 47 Q9UKP4 1.48e-25 A disintegrin and metalloproteinase with thrombospondin motifs 7 (ADAM-TS 7) (ADAM-TS7) (ADAMTS-7) (EC 3.4.24.-) (COMPase) Homo sapiens (Human) cellular response to BMP stimulus [GO:0071773]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; chondrocyte differentiation [GO:0002062]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; negative regulation of chondrocyte differentiation [GO:0032331]; ossification involved in bone maturation [GO:0043931]; proteoglycan metabolic process [GO:0006029]; proteolysis involved in protein catabolic process [GO:0051603] GO:0002062; GO:0004222; GO:0005576; GO:0005788; GO:0006029; GO:0008237; GO:0009986; GO:0030198; GO:0030199; GO:0031012; GO:0032331; GO:0043931; GO:0046872; GO:0051603; GO:0071347; GO:0071356; GO:0071773 27618 XR_006392067.1 12 21 15 3 5 NA NA NA NA NA NA 27619 XR_003822923.2 70 27 67 137 142 NA NA NA NA NA NA 27620 XR_003825172.2 0 0 0 0 15 NA NA NA NA NA NA 27621 XM_029323649.2 474 151 169 304 279 P15535 8.89e-73 Beta-1,4-galactosyltransferase 1 (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (EC 2.4.1.-) (Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase) (Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase) (EC 2.4.1.38) (Lactose synthase A protein) (EC 2.4.1.22) (N-acetyllactosamine synthase) (EC 2.4.1.90) (Nal synthase) (Neolactotriaosylceramide beta-1,4-galactosyltransferase) (EC 2.4.1.275) (UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 1) (UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 1) [Cleaved into: Processed beta-1,4-galactosyltransferase 1] Mus musculus (Mouse) acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; cell population proliferation [GO:0008283]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; epithelial cell proliferation [GO:0050673]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; glycoprotein biosynthetic process [GO:0009101]; glycosylation [GO:0070085]; lactose biosynthetic process [GO:0005989]; lipid metabolic process [GO:0006629]; macrophage migration [GO:1905517]; negative regulation of epithelial cell proliferation [GO:0050680]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein glycosylation [GO:0006486]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]; wound healing [GO:0042060] GO:0000138; GO:0002064; GO:0002526; GO:0003831; GO:0003945; GO:0004461; GO:0005576; GO:0005794; GO:0005886; GO:0005989; GO:0006012; GO:0006486; GO:0006487; GO:0006629; GO:0007155; GO:0007339; GO:0007341; GO:0008092; GO:0008283; GO:0008378; GO:0009101; GO:0009312; GO:0009897; GO:0009986; GO:0016323; GO:0030057; GO:0030145; GO:0030175; GO:0030198; GO:0031526; GO:0032580; GO:0032991; GO:0035250; GO:0042060; GO:0042802; GO:0043014; GO:0043065; GO:0045136; GO:0048487; GO:0050673; GO:0050680; GO:0060046; GO:0060054; GO:0060055; GO:0070085; GO:1905517 27622 XM_029335350.2 0 0 0 0 699 Q5QNQ6 8.95e-154 Oxysterol-binding protein 2 Mus musculus (Mouse) spermatid development [GO:0007286] GO:0005829; GO:0005886; GO:0007286; GO:0015248; GO:0015485; GO:0016020; GO:0032934; GO:0043231; GO:0097038; GO:0097440 27623 XM_029335350.2 0 0 0 0 699 Q5QNQ6 8.53e-76 Oxysterol-binding protein 2 Mus musculus (Mouse) spermatid development [GO:0007286] GO:0005829; GO:0005886; GO:0007286; GO:0015248; GO:0015485; GO:0016020; GO:0032934; GO:0043231; GO:0097038; GO:0097440 27624 XM_044325247.1 0 0 16 0 0 NA NA NA NA NA NA 27625 XM_044317831.1 611 354 336 544 647 O00291 0 Huntingtin-interacting protein 1 (HIP-1) (Huntingtin-interacting protein I) (HIP-I) Homo sapiens (Human) actin filament organization [GO:0007015]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cell differentiation [GO:0030154]; clathrin coat assembly [GO:0048268]; endocytosis [GO:0006897]; neurotransmitter receptor transport [GO:0099637]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000588]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of receptor-mediated endocytosis [GO:0048260]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; protein stabilization [GO:0050821]; regulation of apoptotic process [GO:0042981]; regulation of endocytosis [GO:0030100]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149] GO:0005154; GO:0005200; GO:0005634; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0006897; GO:0006915; GO:0006919; GO:0007015; GO:0016020; GO:0030100; GO:0030136; GO:0030154; GO:0030276; GO:0030665; GO:0032051; GO:0032266; GO:0035091; GO:0035254; GO:0035612; GO:0035615; GO:0042803; GO:0042981; GO:0043231; GO:0043325; GO:0045742; GO:0046982; GO:0048260; GO:0048268; GO:0050821; GO:0051015; GO:0051897; GO:0080025; GO:0097190; GO:0098685; GO:0098793; GO:0098794; GO:0098890; GO:0098978; GO:0099149; GO:0099171; GO:0099637; GO:2000588 27626 XM_029352774.2 98 92 79 77 20 NA NA NA NA NA NA 27627 XM_044320083.1 317 548 92 243 47 P10079 8.3e-146 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 27628 XM_044320083.1 317 548 92 243 47 P10079 3.57e-142 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 27629 XM_044320083.1 317 548 92 243 47 P10079 3.75e-142 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 27630 XM_044320083.1 317 548 92 243 47 P10079 2.44e-135 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 27631 XM_044320083.1 317 548 92 243 47 P10079 9.85e-131 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 27632 XM_044320083.1 317 548 92 243 47 P10079 2.94e-95 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 27633 XM_044320083.1 317 548 92 243 47 P10079 7.28e-87 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 27634 XR_006394497.1 96 76 98 48 109 NA NA NA NA NA NA 27635 XM_044310510.1 0 0 0 25 0 P0C0R5 2.26e-82 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) Rattus norvegicus (Rat) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006623; GO:0010506; GO:0015630; GO:0016236; GO:0016241; GO:0030242; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 27636 XM_029353020.2 23 21 9 0 3 NA NA NA NA NA NA 27637 XM_029348914.2 227 199 254 227 184 P95329 1.04e-112 Malate synthase (EC 2.3.3.9) Myxococcus xanthus (strain DK1622) glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099] GO:0004474; GO:0005737; GO:0006097; GO:0006099 27638 XM_044327373.1 96 128 70 188 220 Q9UI26 1.21e-160 Importin-11 (Imp11) (Ran-binding protein 11) (RanBP11) Homo sapiens (Human) protein import into nucleus [GO:0006606]; ribosomal protein import into nucleus [GO:0006610] GO:0005635; GO:0005654; GO:0005829; GO:0006606; GO:0006610; GO:0031267; GO:0061608 27639 XM_029355869.2 1917 1565 1156 1566 1587 Q8K1Y2 0 Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (nPKC-nu) Mus musculus (Mouse) protein kinase D signaling [GO:0089700]; protein phosphorylation [GO:0006468] GO:0004698; GO:0005524; GO:0005654; GO:0005829; GO:0006468; GO:0016020; GO:0016301; GO:0046872; GO:0089700; GO:0106310 27640 XM_044310682.1 361 383 231 184 353 Q684M4 1.28e-161 Kelch-like ECH-associated protein 1 Sus scrofa (Pig) cellular response to interleukin-4 [GO:0071353]; cellular response to oxidative stress [GO:0034599]; cytoplasmic sequestering of transcription factor [GO:0042994]; in utero embryonic development [GO:0001701]; protein ubiquitination [GO:0016567]; regulation of autophagy [GO:0010506]; regulation of epidermal cell differentiation [GO:0045604]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0001701; GO:0005654; GO:0005737; GO:0005783; GO:0005829; GO:0005884; GO:0006511; GO:0010506; GO:0016234; GO:0016567; GO:0030496; GO:0031463; GO:0034451; GO:0034599; GO:0042802; GO:0042994; GO:0045604; GO:0061629; GO:0071353; GO:0097718 27641 XM_029334074.2 4387 2652 1950 6303 3109 Q8BYF6 7.67e-122 Sodium-coupled monocarboxylate transporter 1 (Electrogenic sodium monocarboxylate cotransporter) (Solute carrier family 5 member 8) Mus musculus (Mouse) apoptotic process [GO:0006915]; monocarboxylic acid transport [GO:0015718]; propanoate transport [GO:0015730]; short-chain fatty acid import [GO:0015913]; sodium ion transport [GO:0006814] GO:0005343; GO:0006814; GO:0006915; GO:0015129; GO:0015293; GO:0015552; GO:0015636; GO:0015718; GO:0015730; GO:0015913; GO:0016324; GO:0031526; GO:0140161 27642 XM_044308971.1 4 26 5 15 66 NA NA NA NA NA NA 27643 XM_029330507.2 0 0 0 0 88 O95149 4.16e-94 Snurportin-1 (RNA U transporter 1) Homo sapiens (Human) protein import into nucleus [GO:0006606]; RNA import into nucleus [GO:0006404]; snRNA import into nucleus [GO:0061015] GO:0000339; GO:0005643; GO:0005654; GO:0005829; GO:0006404; GO:0006606; GO:0042564; GO:0061015; GO:0061608 27644 XM_029342132.2 582 289 251 481 426 Q5SVQ0 1.44e-165 Histone acetyltransferase KAT7 (EC 2.3.1.48) (Histone acetyltransferase binding to ORC1) (Lysine acetyltransferase 7) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (MYST-2) Mus musculus (Mouse) DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication-dependent chromatin disassembly [GO:0140889]; histone H4-K12 acetylation [GO:0043983]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; histone modification [GO:0016570]; internal peptidyl-lysine acetylation [GO:0018393]; natural killer cell differentiation [GO:0001779]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of DNA replication [GO:0045740]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell cycle [GO:0051726]; regulation of cell growth [GO:0001558]; regulation of DNA biosynthetic process [GO:2000278]; regulation of DNA replication [GO:0006275]; regulation of DNA-templated DNA replication initiation [GO:0030174]; regulation of DNA-templated transcription [GO:0006355]; regulation of nucleotide-excision repair [GO:2000819]; response to actinomycin D [GO:0072716]; response to anisomycin [GO:0072739]; response to dithiothreitol [GO:0072720]; response to hydroxyurea [GO:0072710]; response to sorbitol [GO:0072708]; stress-activated protein kinase signaling cascade [GO:0031098]; T cell differentiation [GO:0030217]; transcription initiation-coupled chromatin remodeling [GO:0045815] GO:0000123; GO:0000775; GO:0001558; GO:0001779; GO:0003688; GO:0003712; GO:0004402; GO:0005634; GO:0005654; GO:0005694; GO:0005829; GO:0006260; GO:0006275; GO:0006281; GO:0006355; GO:0008270; GO:0010485; GO:0016570; GO:0018393; GO:0030174; GO:0030217; GO:0031098; GO:0032786; GO:0036408; GO:0036409; GO:0042393; GO:0043981; GO:0043982; GO:0043983; GO:0043994; GO:0043995; GO:0043996; GO:0043997; GO:0044016; GO:0045648; GO:0045740; GO:0045815; GO:0045892; GO:0045944; GO:0051726; GO:0072708; GO:0072710; GO:0072716; GO:0072720; GO:0072739; GO:0090734; GO:0140889; GO:1900182; GO:1902035; GO:2000278; GO:2000819 27645 XM_029324357.2 315 322 81 54 401 NA NA NA NA NA NA 27646 XM_044318627.1 3561 2765 3023 4166 4037 Q8CHN6 0 Sphingosine-1-phosphate lyase 1 (S1PL) (SP-lyase 1) (SPL) (SPL 1) (EC 4.1.2.27) (Sphingosine-1-phosphate aldolase) Rattus norvegicus (Rat) androgen metabolic process [GO:0008209]; apoptotic signaling pathway [GO:0097190]; ceramide metabolic process [GO:0006672]; estrogen metabolic process [GO:0008210]; face morphogenesis [GO:0060325]; fatty acid metabolic process [GO:0006631]; female gonad development [GO:0008585]; fibroblast migration [GO:0010761]; hemopoiesis [GO:0030097]; kidney development [GO:0001822]; Leydig cell differentiation [GO:0033327]; luteinization [GO:0001553]; nitrogen compound metabolic process [GO:0006807]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; post-embryonic development [GO:0009791]; regulation of multicellular organism growth [GO:0040014]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; spermatogenesis [GO:0007283]; sphingolipid catabolic process [GO:0030149]; vasculogenesis [GO:0001570] GO:0001553; GO:0001570; GO:0001822; GO:0005783; GO:0005789; GO:0006631; GO:0006672; GO:0006807; GO:0007283; GO:0008117; GO:0008209; GO:0008210; GO:0008585; GO:0009791; GO:0010761; GO:0030097; GO:0030149; GO:0030170; GO:0033327; GO:0040014; GO:0048008; GO:0048705; GO:0060021; GO:0060325; GO:0097190 27647 XM_044316561.1 97 62 10 53 31 Q8BZM0 1.05e-41 Kelch-like protein 12 (CUL3-interacting protein 1) Mus musculus (Mouse) COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; protein monoubiquitination [GO:0006513]; Wnt signaling pathway [GO:0016055] GO:0006513; GO:0006888; GO:0014029; GO:0014032; GO:0016055; GO:0030127; GO:0030134; GO:0031463; GO:0034451; GO:0042802; GO:0043231; GO:0048208 27648 XM_029346095.2 0 16 0 0 29 NA NA NA NA NA NA 27649 XM_044319948.1 747 331 257 296 85 NA NA NA NA NA NA 27650 XM_044307867.1 127 0 127 440 682 P23468 0 Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48) Homo sapiens (Human) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; neuron differentiation [GO:0030182]; phosphate-containing compound metabolic process [GO:0006796]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse assembly [GO:0051965]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; regulation of immune response [GO:0050776]; regulation of postsynaptic density assembly [GO:0099151]; synaptic membrane adhesion [GO:0099560]; trans-synaptic signaling by trans-synaptic complex [GO:0099545]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185] GO:0004725; GO:0005001; GO:0005102; GO:0005886; GO:0006470; GO:0006796; GO:0007157; GO:0007185; GO:0030182; GO:0042734; GO:0046426; GO:0050775; GO:0050776; GO:0050804; GO:0050839; GO:0051965; GO:0070062; GO:0097105; GO:0098685; GO:0098686; GO:0098978; GO:0099054; GO:0099151; GO:0099545; GO:0099560 27651 XM_044307867.1 127 0 127 440 682 P23468 1.06e-72 Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48) Homo sapiens (Human) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; neuron differentiation [GO:0030182]; phosphate-containing compound metabolic process [GO:0006796]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse assembly [GO:0051965]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; regulation of immune response [GO:0050776]; regulation of postsynaptic density assembly [GO:0099151]; synaptic membrane adhesion [GO:0099560]; trans-synaptic signaling by trans-synaptic complex [GO:0099545]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185] GO:0004725; GO:0005001; GO:0005102; GO:0005886; GO:0006470; GO:0006796; GO:0007157; GO:0007185; GO:0030182; GO:0042734; GO:0046426; GO:0050775; GO:0050776; GO:0050804; GO:0050839; GO:0051965; GO:0070062; GO:0097105; GO:0098685; GO:0098686; GO:0098978; GO:0099054; GO:0099151; GO:0099545; GO:0099560 27652 XM_044307867.1 127 0 127 440 682 P23468 6.76e-68 Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48) Homo sapiens (Human) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; neuron differentiation [GO:0030182]; phosphate-containing compound metabolic process [GO:0006796]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse assembly [GO:0051965]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; regulation of immune response [GO:0050776]; regulation of postsynaptic density assembly [GO:0099151]; synaptic membrane adhesion [GO:0099560]; trans-synaptic signaling by trans-synaptic complex [GO:0099545]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185] GO:0004725; GO:0005001; GO:0005102; GO:0005886; GO:0006470; GO:0006796; GO:0007157; GO:0007185; GO:0030182; GO:0042734; GO:0046426; GO:0050775; GO:0050776; GO:0050804; GO:0050839; GO:0051965; GO:0070062; GO:0097105; GO:0098685; GO:0098686; GO:0098978; GO:0099054; GO:0099151; GO:0099545; GO:0099560 27653 XM_044307867.1 127 0 127 440 682 P23468 2.22e-60 Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48) Homo sapiens (Human) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; neuron differentiation [GO:0030182]; phosphate-containing compound metabolic process [GO:0006796]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse assembly [GO:0051965]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; regulation of immune response [GO:0050776]; regulation of postsynaptic density assembly [GO:0099151]; synaptic membrane adhesion [GO:0099560]; trans-synaptic signaling by trans-synaptic complex [GO:0099545]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185] GO:0004725; GO:0005001; GO:0005102; GO:0005886; GO:0006470; GO:0006796; GO:0007157; GO:0007185; GO:0030182; GO:0042734; GO:0046426; GO:0050775; GO:0050776; GO:0050804; GO:0050839; GO:0051965; GO:0070062; GO:0097105; GO:0098685; GO:0098686; GO:0098978; GO:0099054; GO:0099151; GO:0099545; GO:0099560 27654 XM_044307867.1 127 0 127 440 682 P23468 1.09e-53 Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48) Homo sapiens (Human) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; neuron differentiation [GO:0030182]; phosphate-containing compound metabolic process [GO:0006796]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse assembly [GO:0051965]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; regulation of immune response [GO:0050776]; regulation of postsynaptic density assembly [GO:0099151]; synaptic membrane adhesion [GO:0099560]; trans-synaptic signaling by trans-synaptic complex [GO:0099545]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185] GO:0004725; GO:0005001; GO:0005102; GO:0005886; GO:0006470; GO:0006796; GO:0007157; GO:0007185; GO:0030182; GO:0042734; GO:0046426; GO:0050775; GO:0050776; GO:0050804; GO:0050839; GO:0051965; GO:0070062; GO:0097105; GO:0098685; GO:0098686; GO:0098978; GO:0099054; GO:0099151; GO:0099545; GO:0099560 27655 XM_044307867.1 127 0 127 440 682 P23468 6.85e-45 Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48) Homo sapiens (Human) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; neuron differentiation [GO:0030182]; phosphate-containing compound metabolic process [GO:0006796]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse assembly [GO:0051965]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; regulation of immune response [GO:0050776]; regulation of postsynaptic density assembly [GO:0099151]; synaptic membrane adhesion [GO:0099560]; trans-synaptic signaling by trans-synaptic complex [GO:0099545]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185] GO:0004725; GO:0005001; GO:0005102; GO:0005886; GO:0006470; GO:0006796; GO:0007157; GO:0007185; GO:0030182; GO:0042734; GO:0046426; GO:0050775; GO:0050776; GO:0050804; GO:0050839; GO:0051965; GO:0070062; GO:0097105; GO:0098685; GO:0098686; GO:0098978; GO:0099054; GO:0099151; GO:0099545; GO:0099560 27656 XM_044325864.1 4 0 0 31 0 B8V7S0 2.79e-49 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 27657 XM_044325864.1 4 0 0 31 0 B8V7S0 5.96e-35 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 27658 XM_029323574.2 330 114 273 301 303 NA NA NA NA NA NA 27659 XM_029351326.2 492 348 273 499 410 Q6DDS9 7.01e-151 NA NA NA NA 27660 XM_044321798.1 2880 2357 2523 2900 3214 NA NA NA NA NA NA 27661 XM_044321521.1 46 0 0 0 29 NA NA NA NA NA NA 27662 XR_006392256.1 6 0 0 0 0 NA NA NA NA NA NA 27663 XM_029349795.2 1034 546 488 1145 836 Q56585 7.47e-28 DNA-binding transcriptional regulator BolA Vibrio alginolyticus NA GO:0003677 27664 XR_006393939.1 2 7 2 9 4 NA NA NA NA NA NA 27665 XM_029327016.2 12 15 7 8 7 P54318 1.05e-46 Pancreatic lipase-related protein 2 (PL-RP2) (Cytotoxic T lymphocyte lipase) (Galactolipase) (EC 3.1.1.26) (Secretory glycoprotein GP-3) (Triacylglycerol lipase) (EC 3.1.1.3) Rattus norvegicus (Rat) cellular defense response [GO:0006968]; galactolipid catabolic process [GO:0019376]; intestinal lipid catabolic process [GO:0044258]; lipid catabolic process [GO:0016042]; phosphatidylcholine catabolic process [GO:0034638]; phospholipid catabolic process [GO:0009395]; phospholipid metabolic process [GO:0006644]; post-embryonic development [GO:0009791]; response to bacterium [GO:0009617]; response to food [GO:0032094]; response to glucocorticoid [GO:0051384]; response to lipid [GO:0033993]; response to peptide hormone [GO:0043434]; triglyceride catabolic process [GO:0019433] GO:0004620; GO:0004806; GO:0005509; GO:0005615; GO:0006644; GO:0006968; GO:0009395; GO:0009617; GO:0009791; GO:0016042; GO:0016298; GO:0019376; GO:0019433; GO:0032094; GO:0033993; GO:0034638; GO:0042589; GO:0043005; GO:0043434; GO:0044258; GO:0047372; GO:0047714; GO:0051384; GO:0102549 27666 XM_044327684.1 38 0 22 0 16 NA NA NA NA NA NA 27667 XM_029342896.2 73 58 8 175 0 Q7ZYZ7 4.73e-47 Polycomb group RING finger protein 1 Danio rerio (Zebrafish) (Brachydanio rerio) aging [GO:0007568]; developmental growth [GO:0048589]; histone H2A-K119 monoubiquitination [GO:0036353]; negative regulation of transcription by RNA polymerase II [GO:0000122] GO:0000122; GO:0007568; GO:0031519; GO:0035102; GO:0036353; GO:0046872; GO:0048589; GO:1990841 27668 XM_044317720.1 255 159 200 209 128 Q503V3 5.57e-43 SREBP regulating gene protein Danio rerio (Zebrafish) (Brachydanio rerio) positive regulation of SREBP signaling pathway [GO:2000640] GO:0000139; GO:2000640 27669 XM_029356817.2 97 0 24 27 45 NA NA NA NA NA NA 27670 XM_029338421.2 160 79 94 146 290 Q0IIF7 0 Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.4.19.12) (Deubiquitinating enzyme 14) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) Bos taurus (Bovine) innate immune response [GO:0045087]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; regulation of proteasomal protein catabolic process [GO:0061136] GO:0000502; GO:0004843; GO:0005737; GO:0005886; GO:0016579; GO:0043161; GO:0045087; GO:0061136; GO:0070628 27671 XM_044328207.1 0 0 0 0 9 NA NA NA NA NA NA 27672 XR_006394625.1 0 0 8 0 0 NA NA NA NA NA NA 27673 XM_044310544.1 1 0 9 10 33 Q0WYX8 5.9e-37 MAM domain-containing glycosylphosphatidylinositol anchor protein 1 Gallus gallus (Chicken) neuron migration [GO:0001764] GO:0001764; GO:0005886 27674 XM_044315177.1 223 34 6 5 59 NA NA NA NA NA NA 27675 XM_044325316.1 28 0 0 0 0 Q2KIA4 1.03e-107 Stearoyl-CoA desaturase 5 (EC 1.14.19.1) (Acyl-CoA-desaturase 4) (Stearoyl-CoA 9-desaturase) Bos taurus (Bovine) monounsaturated fatty acid biosynthetic process [GO:1903966]; unsaturated fatty acid biosynthetic process [GO:0006636] GO:0004768; GO:0005506; GO:0005789; GO:0006636; GO:0016491; GO:1903966 27676 XM_029341541.2 4381 2814 3166 2834 2371 Q7KM13 2.84e-23 Hairy/enhancer-of-split related with YRPW motif protein Drosophila melanogaster (Fruit fly) anterior/posterior pattern specification [GO:0009952]; neuron fate determination [GO:0048664]; Notch signaling pathway [GO:0007219]; regulation of neurogenesis [GO:0050767]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0003677; GO:0005634; GO:0006357; GO:0007219; GO:0009952; GO:0046983; GO:0048664; GO:0050767 27677 XR_006396705.1 9 0 0 0 0 NA NA NA NA NA NA 27678 XM_044312284.1 53 0 27 0 46 Q96ND8 2.49e-71 Zinc finger protein 583 (Zinc finger protein L3-5) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 27679 XM_044312284.1 53 0 27 0 46 Q96ND8 4.49e-67 Zinc finger protein 583 (Zinc finger protein L3-5) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 27680 XM_044312284.1 53 0 27 0 46 Q96ND8 1.69e-66 Zinc finger protein 583 (Zinc finger protein L3-5) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 27681 XM_044312284.1 53 0 27 0 46 Q96ND8 4.75e-65 Zinc finger protein 583 (Zinc finger protein L3-5) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 27682 XM_044312284.1 53 0 27 0 46 Q96ND8 9.76e-64 Zinc finger protein 583 (Zinc finger protein L3-5) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 27683 XM_044312284.1 53 0 27 0 46 Q96ND8 3.65e-57 Zinc finger protein 583 (Zinc finger protein L3-5) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 27684 XM_044312284.1 53 0 27 0 46 Q96ND8 1.48e-36 Zinc finger protein 583 (Zinc finger protein L3-5) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 27685 XM_044312284.1 53 0 27 0 46 Q96ND8 5.97e-31 Zinc finger protein 583 (Zinc finger protein L3-5) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 27686 XM_044317010.1 0 0 0 0 16 NA NA NA NA NA NA 27687 XM_029351600.2 0 0 86 29 0 P07700 1.14e-22 Beta-1 adrenergic receptor (Beta-1 adrenoreceptor) (Beta-1 adrenoceptor) (Beta-T) Meleagris gallopavo (Wild turkey) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; positive regulation of GTPase activity [GO:0043547]; positive regulation of heart contraction [GO:0045823]; regulation of circadian sleep/wake cycle, sleep [GO:0045187] GO:0004940; GO:0005085; GO:0005769; GO:0005886; GO:0016020; GO:0042802; GO:0043547; GO:0045187; GO:0045823; GO:0071880 27688 XM_029333710.2 111 43 14 37 22 O95989 1.34e-40 Diphosphoinositol polyphosphate phosphohydrolase 1 (DIPP-1) (EC 3.6.1.52) (Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 1) (EC 3.6.1.-) (Nucleoside diphosphate-linked moiety X motif 3) (Nudix motif 3) Homo sapiens (Human) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process [GO:1901911]; cell-cell signaling [GO:0007267]; diadenosine hexaphosphate catabolic process [GO:1901909]; diadenosine pentaphosphate catabolic process [GO:1901907]; diadenosine polyphosphate catabolic process [GO:0015961]; diphosphoinositol polyphosphate catabolic process [GO:0071544]; diphosphoinositol polyphosphate metabolic process [GO:0071543]; RNA decapping [GO:0110154] GO:0000287; GO:0000298; GO:0005634; GO:0005737; GO:0005829; GO:0007267; GO:0008486; GO:0015961; GO:0034431; GO:0034432; GO:0050072; GO:0052840; GO:0052842; GO:0052845; GO:0052848; GO:0071543; GO:0071544; GO:0110154; GO:1901907; GO:1901909; GO:1901911 27689 XM_044308866.1 572 3491 705 1449 589 Q07646 1.36e-98 Mesoderm-specific transcript protein (EC 3.-.-.-) (Paternally-expressed gene 1 protein) Mus musculus (Mouse) regulation of lipid storage [GO:0010883]; response to retinoic acid [GO:0032526] GO:0005783; GO:0005789; GO:0010883; GO:0016787; GO:0032526 27690 XR_003825696.2 231 0 0 10 0 NA NA NA NA NA NA 27691 XM_044315303.1 78 75 43 107 58 NA NA NA NA NA NA 27692 XM_029330994.2 143 151 129 29 45 NA NA NA NA NA NA 27693 XM_029331505.2 166 101 53 205 192 NA NA NA NA NA NA 27694 XM_029344155.2 1069 1878 1291 997 1529 P78318 6.81e-40 Immunoglobulin-binding protein 1 (B-cell signal transduction molecule alpha 4) (Protein alpha-4) (CD79a-binding protein 1) (Protein phosphatase 2/4/6 regulatory subunit) (Renal carcinoma antigen NY-REN-16) Homo sapiens (Human) B cell activation [GO:0042113]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of dephosphorylation [GO:0035303]; regulation of microtubule-based movement [GO:0060632]; response to interleukin-1 [GO:0070555]; response to tumor necrosis factor [GO:0034612]; signal transduction [GO:0007165] GO:0000122; GO:0005737; GO:0005829; GO:0007165; GO:0019888; GO:0032873; GO:0034612; GO:0035303; GO:0042113; GO:0043154; GO:0051721; GO:0060632; GO:0070555 27695 XM_044323156.1 80 27 46 20 134 Q5R5U3 0 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 27696 XM_044323156.1 80 27 46 20 134 Q5R5U3 0 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 27697 XM_044323156.1 80 27 46 20 134 Q5R5U3 2.23e-178 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 27698 XM_044323156.1 80 27 46 20 134 Q5R5U3 2.19e-177 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 27699 XM_044323156.1 80 27 46 20 134 Q5R5U3 7.86e-166 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 27700 XM_044323156.1 80 27 46 20 134 Q5R5U3 1.03e-105 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 27701 XM_044308144.1 725 506 231 420 369 P79384 0 Propionyl-CoA carboxylase beta chain, mitochondrial (PCCase subunit beta) (EC 6.4.1.3) (Propanoyl-CoA:carbon dioxide ligase subunit beta) Sus scrofa (Pig) short-chain fatty acid catabolic process [GO:0019626] GO:0004658; GO:0005524; GO:0005739; GO:0005759; GO:0019626 27702 XM_029333598.2 62 10 30 33 36 NA NA NA NA NA NA 27703 XM_029346258.2 51 28 41 80 148 NA NA NA NA NA NA 27704 XR_003828237.2 68 73 8 21 29 NA NA NA NA NA NA 27705 XM_044307693.1 223 157 174 118 956 P36410 3.81e-31 Ras-related protein Rab-14 (Rab4-like GTPase) Dictyostelium discoideum (Social amoeba) contractile vacuole organization [GO:0033298]; defense response to bacterium [GO:0042742]; endocytic recycling [GO:0032456]; Golgi to endosome transport [GO:0006895]; intracellular protein transport [GO:0006886]; phagolysosome assembly involved in apoptotic cell clearance [GO:0090387]; regulation of endosomal vesicle fusion [GO:1905364]; regulation of pinocytosis [GO:0048548]; response to osmotic stress [GO:0006970] GO:0003924; GO:0005525; GO:0005764; GO:0005765; GO:0005769; GO:0005802; GO:0005811; GO:0005829; GO:0006886; GO:0006895; GO:0006970; GO:0012505; GO:0031164; GO:0032456; GO:0033298; GO:0042742; GO:0045335; GO:0048548; GO:0055037; GO:0062160; GO:0090387; GO:0140220; GO:1905364 27706 XM_044318236.1 2 16 21 11 39 E7FAM5 2.01e-85 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 27707 XM_029337738.2 4039 2803 3569 3538 4218 Q9UPY6 2.31e-59 Actin-binding protein WASF3 (Protein WAVE-3) (Verprolin homology domain-containing protein 3) (Wiskott-Aldrich syndrome protein family member 3) (WASP family protein member 3) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; actin filament polymerization [GO:0030041]; cytoskeleton organization [GO:0007010]; lamellipodium assembly [GO:0030032]; modification of postsynaptic actin cytoskeleton [GO:0098885]; oligodendrocyte development [GO:0014003]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601]; positive regulation of myelination [GO:0031643]; protein-containing complex assembly [GO:0065003]; regulation of cell shape [GO:0008360] GO:0003779; GO:0005856; GO:0007010; GO:0008360; GO:0014003; GO:0030027; GO:0030032; GO:0030036; GO:0030041; GO:0031209; GO:0031643; GO:0034237; GO:0065003; GO:0070062; GO:0071933; GO:0097386; GO:0098794; GO:0098885; GO:0098978; GO:2000601 27708 XM_044328220.1 661 561 353 608 762 Q0VC33 8.69e-35 Tetraspanin-11 (Tspan-11) Bos taurus (Bovine) cell migration [GO:0016477] GO:0005886; GO:0016477 27709 XM_044328838.1 0 0 15 0 3 NA NA NA NA NA NA 27710 XM_029348595.2 2118 1165 1278 1826 1316 Q7TPD0 0 Integrator complex subunit 3 (Int3) (SOSS complex subunit A) (Sensor of single-strand DNA complex subunit A) (SOSS-A) (Sensor of ssDNA subunit A) Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; mitotic G2/M transition checkpoint [GO:0044818]; response to ionizing radiation [GO:0010212]; snRNA processing [GO:0016180] GO:0000724; GO:0005634; GO:0005737; GO:0006281; GO:0006974; GO:0010212; GO:0016180; GO:0032039; GO:0035861; GO:0044818; GO:0070876 27711 XR_003825445.2 0 3 1 6 30 NA NA NA NA NA NA 27712 XM_029338194.2 283 200 403 169 349 A4II73 1.63e-55 Esterase OVCA2 (EC 3.1.2.-) (Ovarian cancer-associated gene 2 protein homolog) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0016787 27713 XR_006393667.1 19 16 24 1 65 NA NA NA NA NA NA 27714 XM_029337180.2 0 0 5 9 0 NA NA NA NA NA NA 27715 XM_044319911.1 92 86 105 194 150 Q923S9 3.9e-54 Ras-related protein Rab-30 Mus musculus (Mouse) Golgi organization [GO:0007030]; Rab protein signal transduction [GO:0032482]; vesicle-mediated transport [GO:0016192] GO:0003924; GO:0005525; GO:0005801; GO:0005802; GO:0007030; GO:0016020; GO:0016192; GO:0031985; GO:0032482; GO:0043231 27716 XM_044317000.1 3076 2580 1830 4853 4064 Q99K85 1.62e-163 Phosphoserine aminotransferase (PSAT) (EC 2.6.1.52) (Endometrial progesterone-induced protein) (EPIP) (Phosphohydroxythreonine aminotransferase) Mus musculus (Mouse) L-serine biosynthetic process [GO:0006564] GO:0004648; GO:0005737; GO:0005829; GO:0006564; GO:0030170; GO:0042802 27717 XR_006394542.1 1 0 0 25 35 NA NA NA NA NA NA 27718 XM_044324835.1 0 0 19 0 30 P35061 9.57e-85 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 27719 XM_044319421.1 1 16 14 4 3 A9ZSY3 3.56e-96 Facilitated trehalose transporter Tret1 (BmTRET1) Bombyx mori (Silk moth) trehalose transport [GO:0015771] GO:0005886; GO:0015574; GO:0015771; GO:0051119 27720 XM_029333264.2 0 0 0 23 0 Q16281 0 Cyclic nucleotide-gated cation channel alpha-3 (Cone photoreceptor cGMP-gated channel subunit alpha) (Cyclic nucleotide-gated channel alpha-3) (CNG channel alpha-3) (CNG-3) (CNG3) Homo sapiens (Human) cation transmembrane transport [GO:0098655]; cation transport [GO:0006812]; inorganic cation import across plasma membrane [GO:0098659]; response to cAMP [GO:0051591]; response to corticosteroid [GO:0031960]; response to magnesium ion [GO:0032026]; signal transduction [GO:0007165]; visual perception [GO:0007601] GO:0005222; GO:0005223; GO:0005737; GO:0005886; GO:0006812; GO:0007165; GO:0007601; GO:0008022; GO:0015276; GO:0017071; GO:0030425; GO:0030553; GO:0031960; GO:0032026; GO:0043194; GO:0043204; GO:0044877; GO:0051591; GO:0097386; GO:0098655; GO:0098659; GO:1902495 27721 XM_029334623.2 0 190 29 329 0 Q8TE60 1.36e-130 A disintegrin and metalloproteinase with thrombospondin motifs 18 (ADAM-TS 18) (ADAM-TS18) (ADAMTS-18) (EC 3.4.24.-) Homo sapiens (Human) extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; negative regulation of platelet aggregation [GO:0090331]; proteolysis [GO:0006508] GO:0001654; GO:0004222; GO:0005576; GO:0006508; GO:0030198; GO:0031012; GO:0046872; GO:0090331 27722 XM_029326078.2 0 0 12 134 206 Q9UHR5 1.17e-27 SAP30-binding protein (Transcriptional regulator protein HCNGP) Homo sapiens (Human) modulation by host of symbiont transcription [GO:0052472]; positive regulation of histone deacetylation [GO:0031065]; regulation of DNA-templated transcription [GO:0006355]; response to virus [GO:0009615] GO:0005634; GO:0005654; GO:0006355; GO:0009615; GO:0031065; GO:0045111; GO:0052472 27723 XM_044309631.1 12 9 11 9 5 NA NA NA NA NA NA 27724 XM_029349845.2 453 0 62 135 334 NA NA NA NA NA NA 27725 XM_044312578.1 281 205 69 213 138 Q6NUB7 0 Ubiquitin thioesterase zranb1-B (EC 3.4.19.12) (Zinc finger Ran-binding domain-containing protein 1B) Xenopus laevis (African clawed frog) cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; positive regulation of Wnt signaling pathway [GO:0030177]; protein K29-linked deubiquitination [GO:0035523]; protein K33-linked deubiquitination [GO:1990168]; protein K63-linked deubiquitination [GO:0070536]; regulation of cell morphogenesis [GO:0022604]; Wnt signaling pathway [GO:0016055] GO:0004843; GO:0005634; GO:0005737; GO:0007010; GO:0016055; GO:0016477; GO:0022604; GO:0030177; GO:0035523; GO:0046872; GO:0070536; GO:1990168 27726 XM_029348741.2 9 0 7 0 10 NA NA NA NA NA NA 27727 XM_044321461.1 171 0 0 0 113 Q0P4F7 0 Medium-chain acyl-CoA ligase ACSF2, mitochondrial (EC 6.2.1.2) Danio rerio (Zebrafish) (Brachydanio rerio) fatty acid metabolic process [GO:0006631] GO:0005524; GO:0005739; GO:0006631; GO:0031956; GO:0047760 27728 XM_029337116.2 0 47 0 0 5 Q5F2F2 2.18e-61 Protein ABHD15 (Alpha/beta hydrolase domain-containing protein 15) (Abhydrolase domain-containing protein 15) Mus musculus (Mouse) cellular lipid metabolic process [GO:0044255] GO:0005576; GO:0034338; GO:0044255; GO:0047372 27729 XM_029350417.2 1043 631 433 921 546 Q8WXR4 4.65e-128 Myosin-IIIb (EC 2.7.11.1) Homo sapiens (Human) cochlea morphogenesis [GO:0090103]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of filopodium assembly [GO:0051491]; regulation of actin filament length [GO:0030832]; response to stimulus [GO:0050896]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] GO:0000146; GO:0001917; GO:0003779; GO:0004674; GO:0005524; GO:0005737; GO:0007601; GO:0007605; GO:0016459; GO:0018105; GO:0030832; GO:0032426; GO:0032433; GO:0050896; GO:0051491; GO:0090103; GO:0106310 27730 XM_044311768.1 9 0 0 13 16 NA NA NA NA NA NA 27731 XM_029344227.2 0 3 0 15 0 NA NA NA NA NA NA 27732 XR_006391865.1 1668 31 136 287 539 NA NA NA NA NA NA 27733 XM_044308942.1 0 10 7 7 5 NA NA NA NA NA NA 27734 XM_029345312.2 515 491 338 379 562 P98155 4.82e-155 Very low-density lipoprotein receptor (VLDL receptor) (VLDL-R) Homo sapiens (Human) cholesterol metabolic process [GO:0008203]; dendrite morphogenesis [GO:0048813]; glycoprotein transport [GO:0034436]; lipid transport [GO:0006869]; memory [GO:0007613]; nervous system development [GO:0007399]; positive regulation of dendrite development [GO:1900006]; positive regulation of protein kinase activity [GO:0045860]; receptor-mediated endocytosis [GO:0006898]; reelin-mediated signaling pathway [GO:0038026]; signal transduction [GO:0007165]; ventral spinal cord development [GO:0021517]; very-low-density lipoprotein particle clearance [GO:0034447] GO:0005041; GO:0005509; GO:0005765; GO:0005886; GO:0005905; GO:0006869; GO:0006898; GO:0007165; GO:0007399; GO:0007613; GO:0008203; GO:0016020; GO:0021517; GO:0030229; GO:0034185; GO:0034189; GO:0034361; GO:0034436; GO:0034447; GO:0038024; GO:0038025; GO:0038026; GO:0043235; GO:0045860; GO:0048306; GO:0048813; GO:1900006 27735 XM_044325906.1 18 9 12 35 24 NA NA NA NA NA NA 27736 XM_044314226.1 13 8 0 35 28 NA NA NA NA NA NA 27737 XM_044310281.1 309 22 90 220 315 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27738 XM_044310281.1 309 22 90 220 315 Q96AY4 1.27e-170 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27739 XM_044310281.1 309 22 90 220 315 Q96AY4 8.54e-98 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27740 XM_044310281.1 309 22 90 220 315 Q96AY4 1.9e-95 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27741 XM_044310281.1 309 22 90 220 315 Q96AY4 1.11e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27742 XR_003822989.2 20 28 66 12 32 NA NA NA NA NA NA 27743 XM_029337969.2 831 71 99 1310 645 O00339 1.34e-49 Matrilin-2 Homo sapiens (Human) extracellular matrix organization [GO:0030198] GO:0005201; GO:0005509; GO:0005576; GO:0030198; GO:0031012; GO:0062023; GO:0120216 27744 XM_029337969.2 831 71 99 1310 645 O00339 9.02e-40 Matrilin-2 Homo sapiens (Human) extracellular matrix organization [GO:0030198] GO:0005201; GO:0005509; GO:0005576; GO:0030198; GO:0031012; GO:0062023; GO:0120216 27745 XM_029337969.2 831 71 99 1310 645 O00339 7.81e-31 Matrilin-2 Homo sapiens (Human) extracellular matrix organization [GO:0030198] GO:0005201; GO:0005509; GO:0005576; GO:0030198; GO:0031012; GO:0062023; GO:0120216 27746 XM_029337969.2 831 71 99 1310 645 O00339 1.26e-30 Matrilin-2 Homo sapiens (Human) extracellular matrix organization [GO:0030198] GO:0005201; GO:0005509; GO:0005576; GO:0030198; GO:0031012; GO:0062023; GO:0120216 27747 XM_029337969.2 831 71 99 1310 645 O00339 3.63e-30 Matrilin-2 Homo sapiens (Human) extracellular matrix organization [GO:0030198] GO:0005201; GO:0005509; GO:0005576; GO:0030198; GO:0031012; GO:0062023; GO:0120216 27748 XM_029337969.2 831 71 99 1310 645 O00339 2.92e-22 Matrilin-2 Homo sapiens (Human) extracellular matrix organization [GO:0030198] GO:0005201; GO:0005509; GO:0005576; GO:0030198; GO:0031012; GO:0062023; GO:0120216 27749 XM_044317910.1 44 0 0 27 35 O15439 0 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 27750 XM_044319104.1 78 90 21 109 27 NA NA NA NA NA NA 27751 XM_044326421.1 3 5 9 3 32 NA NA NA NA NA NA 27752 XM_029344040.2 135 35 68 112 100 Q8MPM1 1.34e-57 Gelsolin-like protein 2 (Actin-modulator) (EWAM-P2) Lumbricus terrestris (Common earthworm) actin filament capping [GO:0051693] GO:0005737; GO:0005856; GO:0051015; GO:0051693 27753 XM_044321181.1 44 53 56 75 116 NA NA NA NA NA NA 27754 XM_044321106.1 1028 740 458 934 833 Q90512 2.68e-156 Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial (EC 2.3.1.61) (2-oxoglutarate dehydrogenase complex component E2) (OGDC-E2) (Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex) (E2K) Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) 2-oxoglutarate metabolic process [GO:0006103]; histone succinylation [GO:0106077]; L-lysine catabolic process to acetyl-CoA via saccharopine [GO:0033512]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099] GO:0004149; GO:0005634; GO:0005739; GO:0005759; GO:0006099; GO:0006103; GO:0006104; GO:0033512; GO:0045252; GO:0106077 27755 XM_044324169.1 1861 930 1146 2382 2996 Q9BZC7 0 ATP-binding cassette sub-family A member 2 (EC 7.6.2.-) (ATP-binding cassette transporter 2) (ATP-binding cassette 2) Homo sapiens (Human) cellular sphingolipid homeostasis [GO:0090156]; central nervous system myelin formation [GO:0032289]; ceramide translocation [GO:0099040]; cholesterol homeostasis [GO:0042632]; ganglioside metabolic process [GO:0001573]; glycosphingolipid metabolic process [GO:0006687]; lipid metabolic process [GO:0006629]; lipid transport [GO:0006869]; locomotory behavior [GO:0007626]; negative regulation of cholesterol efflux [GO:0090370]; negative regulation of intracellular cholesterol transport [GO:0032384]; negative regulation of low-density lipoprotein receptor activity [GO:1905598]; negative regulation of phospholipid biosynthetic process [GO:0071072]; negative regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905601]; negative regulation of sphingolipid biosynthetic process [GO:0090155]; negative regulation of steroid metabolic process [GO:0045939]; positive regulation of amyloid precursor protein biosynthetic process [GO:0042986]; positive regulation of amyloid precursor protein catabolic process [GO:1902993]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of low-density lipoprotein particle receptor catabolic process [GO:0032805]; regulation of intracellular cholesterol transport [GO:0032383]; regulation of post-translational protein modification [GO:1901873]; regulation of protein glycosylation [GO:0060049]; regulation of protein localization to cell periphery [GO:1904375]; regulation of protein localization to cell surface [GO:2000008]; regulation of steroid metabolic process [GO:0019218]; response to cholesterol [GO:0070723]; response to steroid hormone [GO:0048545]; response to xenobiotic stimulus [GO:0009410]; sphingomyelin metabolic process [GO:0006684]; sphingosine biosynthetic process [GO:0046512]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104] GO:0000166; GO:0001573; GO:0005319; GO:0005524; GO:0005764; GO:0005765; GO:0005768; GO:0005815; GO:0005886; GO:0006629; GO:0006684; GO:0006687; GO:0006869; GO:0007626; GO:0009410; GO:0010008; GO:0016020; GO:0016887; GO:0019218; GO:0031410; GO:0032289; GO:0032383; GO:0032384; GO:0032805; GO:0042626; GO:0042632; GO:0042986; GO:0043190; GO:0043231; GO:0045939; GO:0046512; GO:0048545; GO:0055085; GO:0060049; GO:0061135; GO:0070723; GO:0071072; GO:0090155; GO:0090156; GO:0090370; GO:0099038; GO:0099040; GO:0140359; GO:0150104; GO:1901873; GO:1902004; GO:1902993; GO:1904375; GO:1905598; GO:1905601; GO:2000008 27756 XM_044324169.1 1861 930 1146 2382 2996 Q9BZC7 1.57e-21 ATP-binding cassette sub-family A member 2 (EC 7.6.2.-) (ATP-binding cassette transporter 2) (ATP-binding cassette 2) Homo sapiens (Human) cellular sphingolipid homeostasis [GO:0090156]; central nervous system myelin formation [GO:0032289]; ceramide translocation [GO:0099040]; cholesterol homeostasis [GO:0042632]; ganglioside metabolic process [GO:0001573]; glycosphingolipid metabolic process [GO:0006687]; lipid metabolic process [GO:0006629]; lipid transport [GO:0006869]; locomotory behavior [GO:0007626]; negative regulation of cholesterol efflux [GO:0090370]; negative regulation of intracellular cholesterol transport [GO:0032384]; negative regulation of low-density lipoprotein receptor activity [GO:1905598]; negative regulation of phospholipid biosynthetic process [GO:0071072]; negative regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905601]; negative regulation of sphingolipid biosynthetic process [GO:0090155]; negative regulation of steroid metabolic process [GO:0045939]; positive regulation of amyloid precursor protein biosynthetic process [GO:0042986]; positive regulation of amyloid precursor protein catabolic process [GO:1902993]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of low-density lipoprotein particle receptor catabolic process [GO:0032805]; regulation of intracellular cholesterol transport [GO:0032383]; regulation of post-translational protein modification [GO:1901873]; regulation of protein glycosylation [GO:0060049]; regulation of protein localization to cell periphery [GO:1904375]; regulation of protein localization to cell surface [GO:2000008]; regulation of steroid metabolic process [GO:0019218]; response to cholesterol [GO:0070723]; response to steroid hormone [GO:0048545]; response to xenobiotic stimulus [GO:0009410]; sphingomyelin metabolic process [GO:0006684]; sphingosine biosynthetic process [GO:0046512]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104] GO:0000166; GO:0001573; GO:0005319; GO:0005524; GO:0005764; GO:0005765; GO:0005768; GO:0005815; GO:0005886; GO:0006629; GO:0006684; GO:0006687; GO:0006869; GO:0007626; GO:0009410; GO:0010008; GO:0016020; GO:0016887; GO:0019218; GO:0031410; GO:0032289; GO:0032383; GO:0032384; GO:0032805; GO:0042626; GO:0042632; GO:0042986; GO:0043190; GO:0043231; GO:0045939; GO:0046512; GO:0048545; GO:0055085; GO:0060049; GO:0061135; GO:0070723; GO:0071072; GO:0090155; GO:0090156; GO:0090370; GO:0099038; GO:0099040; GO:0140359; GO:0150104; GO:1901873; GO:1902004; GO:1902993; GO:1904375; GO:1905598; GO:1905601; GO:2000008 27757 XR_006393378.1 61 20 0 4 89 NA NA NA NA NA NA 27758 XM_029335307.2 245 88 117 276 363 NA NA NA NA NA NA 27759 XM_029345373.2 550 356 380 533 914 Q9NVI1 0 Fanconi anemia group I protein (Protein FACI) Homo sapiens (Human) cell cycle [GO:0007049]; interstrand cross-link repair [GO:0036297]; positive regulation of protein ubiquitination [GO:0031398] GO:0000785; GO:0003677; GO:0005654; GO:0005737; GO:0005829; GO:0007049; GO:0016020; GO:0031398; GO:0036297; GO:0070182; GO:1990391 27760 XM_044316695.1 7 20 12 13 8 NA NA NA NA NA NA 27761 XR_003826671.2 1773 1943 868 1407 1703 NA NA NA NA NA NA 27762 XM_044309839.1 127 295 76 606 82 Q29RU2 2.2e-43 Oncoprotein-induced transcript 3 protein Bos taurus (Bovine) NA GO:0005509; GO:0005635 27763 XM_029338689.2 513 421 103 128 308 Q02447 2.13e-40 Transcription factor Sp3 (SPR-2) Homo sapiens (Human) B cell differentiation [GO:0030183]; definitive hemopoiesis [GO:0060216]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic placenta development [GO:0001892]; embryonic process involved in female pregnancy [GO:0060136]; embryonic skeletal system development [GO:0048706]; enucleate erythrocyte differentiation [GO:0043353]; granulocyte differentiation [GO:0030851]; liver development [GO:0001889]; lung development [GO:0030324]; megakaryocyte differentiation [GO:0030219]; monocyte differentiation [GO:0030224]; myeloid progenitor cell differentiation [GO:0002318]; natural killer cell differentiation [GO:0001779]; negative regulation of DNA-templated transcription [GO:0045892]; ossification [GO:0001503]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; T cell differentiation [GO:0030217]; trophectodermal cell differentiation [GO:0001829] GO:0000785; GO:0000977; GO:0000978; GO:0000981; GO:0001227; GO:0001503; GO:0001779; GO:0001829; GO:0001889; GO:0001892; GO:0002318; GO:0003682; GO:0005634; GO:0005654; GO:0005829; GO:0006355; GO:0006357; GO:0016605; GO:0017053; GO:0030183; GO:0030217; GO:0030219; GO:0030224; GO:0030324; GO:0030851; GO:0032993; GO:0043353; GO:0045892; GO:0045893; GO:0045944; GO:0046872; GO:0048596; GO:0048706; GO:0060136; GO:0060216; GO:0061629; GO:1990837 27764 XM_044323621.1 0 0 0 91 147 NA NA NA NA NA NA 27765 XM_044316925.1 18 0 21 21 24 NA NA NA NA NA NA 27766 XM_029356157.2 258 54 0 0 0 Q7ZWG6 1.95e-59 Proton-coupled folate transporter (Solute carrier family 46 member 1) Danio rerio (Zebrafish) (Brachydanio rerio) transmembrane transport [GO:0055085] GO:0005542; GO:0005768; GO:0005886; GO:0010008; GO:0015293; GO:0015350; GO:0016020; GO:0016323; GO:0016324; GO:0022857; GO:0055085 27767 XM_029331620.2 1383 1702 1317 1235 811 Q1L9A2 1.94e-43 Optic atrophy 3 protein homolog Danio rerio (Zebrafish) (Brachydanio rerio) locomotory behavior [GO:0007626]; musculoskeletal movement [GO:0050881]; regulation of buoyancy [GO:0031413]; regulation of lipid metabolic process [GO:0019216] GO:0005739; GO:0007626; GO:0019216; GO:0031413; GO:0050881 27768 XM_029326992.2 78 0 0 3 3 Q8BYI6 9.59e-143 Lysophosphatidylcholine acyltransferase 2 (LPC acyltransferase 2) (LPCAT-2) (LysoPC acyltransferase 2) (EC 2.3.1.23) (1-acylglycerol-3-phosphate O-acyltransferase 11) (1-AGP acyltransferase 11) (1-AGPAT 11) (EC 2.3.1.51) (1-acylglycerophosphocholine O-acyltransferase) (1-alkenylglycerophosphocholine O-acyltransferase) (EC 2.3.1.25) (1-alkylglycerophosphocholine O-acetyltransferase) (EC 2.3.1.67) (Acetyl-CoA:lyso-platelet-activating factor acetyltransferase) (Acetyl-CoA:lyso-PAF acetyltransferase) (Lyso-PAF acetyltransferase) (LysoPAFAT) (Acyltransferase-like 1) Mus musculus (Mouse) membrane organization [GO:0061024]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; platelet activating factor biosynthetic process [GO:0006663] GO:0000139; GO:0003841; GO:0005509; GO:0005783; GO:0005789; GO:0005795; GO:0005811; GO:0005886; GO:0006663; GO:0016020; GO:0036151; GO:0047159; GO:0047184; GO:0047192; GO:0050200; GO:0061024 27769 XR_006391767.1 104 437 82 166 189 P0DXC0 7.2e-74 NA NA NA NA 27770 XR_006391767.1 104 437 82 166 189 P0DXC0 1.86e-29 NA NA NA NA 27771 XR_003826991.2 1648 1379 550 1227 873 NA NA NA NA NA NA 27772 XM_029341890.2 5509 5167 3562 5747 4057 P35224 0 Catenin beta (Beta-catenin) Urechis caupo (Innkeeper worm) (Spoonworm) cell adhesion [GO:0007155] GO:0005737; GO:0005856; GO:0007155; GO:0045296 27773 XM_029354313.2 545 329 37 148 88 NA NA NA NA NA NA 27774 XR_006391692.1 1 0 19 0 193 NA NA NA NA NA NA 27775 XM_044326902.1 4 66 236 38 107 NA NA NA NA NA NA 27776 XM_044321281.1 260 271 332 589 486 B6ELU0 1.63e-40 tRNA-cytidine(32) 2-sulfurtransferase (EC 2.8.1.-) (Two-thiocytidine biosynthesis protein A) (tRNA 2-thiocytidine biosynthesis protein TtcA) Aliivibrio salmonicida (strain LFI1238) (Vibrio salmonicida (strain LFI1238)) tRNA thio-modification [GO:0034227] GO:0000049; GO:0000287; GO:0005524; GO:0005737; GO:0016783; GO:0034227; GO:0051539 27777 XM_044316961.1 2 18 14 21 18 NA NA NA NA NA NA 27778 XM_029356290.2 208 167 0 194 140 NA NA NA NA NA NA 27779 XM_029331779.2 0 0 20 0 10 NA NA NA NA NA NA 27780 XM_029355966.2 12 3 9 0 2 NA NA NA NA NA NA 27781 XM_044307665.1 258 10 141 108 103 NA NA NA NA NA NA 27782 XM_044316013.1 13 0 33 0 4 NA NA NA NA NA NA 27783 XM_044320567.1 17 772 162 592 785 NA NA NA NA NA NA 27784 XM_029338727.2 130 56 62 71 132 Q5FWF5 3.38e-47 N-acetyltransferase ESCO1 (EC 2.3.1.-) (CTF7 homolog 1) (Establishment factor-like protein 1) (EFO1) (EFO1p) (hEFO1) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) Homo sapiens (Human) mitotic sister chromatid cohesion [GO:0007064]; peptidyl-lysine acetylation [GO:0018394]; post-translational protein acetylation [GO:0034421]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0005634; GO:0005654; GO:0005694; GO:0006275; GO:0007064; GO:0008080; GO:0008270; GO:0016407; GO:0018394; GO:0034421; GO:0042802; GO:0061733 27785 XM_044307689.1 5 0 1 0 14 NA NA NA NA NA NA 27786 XM_029338397.2 0 25 0 0 0 Q6DRD9 3.02e-52 Protein ABHD11 (EC 3.-.-.-) (Alpha/beta hydrolase domain-containing protein 11) (Abhydrolase domain-containing protein 11) (Williams-Beuren syndrome chromosomal region 21 protein homolog) Danio rerio (Zebrafish) (Brachydanio rerio) cellular lipid metabolic process [GO:0044255] GO:0005739; GO:0016787; GO:0044255 27787 XM_044318544.1 26 5 0 11 0 O75899 1.95e-88 Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51) (HG20) Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway [GO:0007186]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; neuron-glial cell signaling [GO:0150099]; synaptic transmission, GABAergic [GO:0051932] GO:0004888; GO:0004965; GO:0005737; GO:0005886; GO:0007186; GO:0007193; GO:0007194; GO:0007214; GO:0007268; GO:0038039; GO:0043005; GO:0045211; GO:0046982; GO:0051932; GO:0150099; GO:1902710; GO:1902712 27788 XM_044314878.1 152 58 98 115 398 NA NA NA NA NA NA 27789 XM_029355601.2 79 20 0 56 28 NA NA NA NA NA NA 27790 XM_029349665.2 131 0 0 17 20 P51611 0 Host cell factor 1 (HCF) (HCF-1) (C1 factor) (VCAF) (VP16 accessory protein) [Cleaved into: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6] Mesocricetus auratus (Golden hamster) cell cycle [GO:0007049]; chromatin organization [GO:0006325]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of mitotic cell cycle [GO:0045931]; protein stabilization [GO:0050821] GO:0000122; GO:0000123; GO:0003682; GO:0003713; GO:0005634; GO:0005737; GO:0006325; GO:0007049; GO:0043025; GO:0045931; GO:0048188; GO:0050821; GO:0071339 27791 XM_029349665.2 131 0 0 17 20 P51611 2.75e-75 Host cell factor 1 (HCF) (HCF-1) (C1 factor) (VCAF) (VP16 accessory protein) [Cleaved into: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6] Mesocricetus auratus (Golden hamster) cell cycle [GO:0007049]; chromatin organization [GO:0006325]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of mitotic cell cycle [GO:0045931]; protein stabilization [GO:0050821] GO:0000122; GO:0000123; GO:0003682; GO:0003713; GO:0005634; GO:0005737; GO:0006325; GO:0007049; GO:0043025; GO:0045931; GO:0048188; GO:0050821; GO:0071339 27792 XM_029337624.2 9 1 12 0 0 NA NA NA NA NA NA 27793 XM_029344914.2 56 3 78 30 137 NA NA NA NA NA NA 27794 XM_029340223.2 15 565 212 29 133 Q8NKE2 7.61e-79 Alternative oxidase, mitochondrial (EC 1.-.-.-) Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii) NA GO:0005743; GO:0009916; GO:0046872; GO:0070469 27795 XM_044324326.1 194 0 0 0 24 NA NA NA NA NA NA 27796 XM_044327059.1 807 436 287 653 593 NA NA NA NA NA NA 27797 XM_044329179.1 7010 7927 3190 10741 6893 A4UTP7 2.24e-63 Myocyte-specific enhancer factor 2C Sus scrofa (Pig) B cell homeostasis [GO:0001782]; B cell proliferation [GO:0042100]; B cell receptor signaling pathway [GO:0050853]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cardiac ventricle formation [GO:0003211]; cardiocyte differentiation [GO:0035051]; cellular response to calcium ion [GO:0071277]; cellular response to fluid shear stress [GO:0071498]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cellular response to trichostatin A [GO:0035984]; cellular response to xenobiotic stimulus [GO:0071466]; chondrocyte differentiation [GO:0002062]; endochondral ossification [GO:0001958]; epithelial cell proliferation involved in renal tubule morphogenesis [GO:2001013]; germinal center formation [GO:0002467]; glomerulus morphogenesis [GO:0072102]; heart development [GO:0007507]; heart looping [GO:0001947]; humoral immune response [GO:0006959]; learning or memory [GO:0007611]; MAPK cascade [GO:0000165]; melanocyte differentiation [GO:0030318]; muscle cell fate determination [GO:0007521]; negative regulation of gene expression [GO:0010629]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of ossification [GO:0030279]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nephron tubule epithelial cell differentiation [GO:0072160]; neural crest cell differentiation [GO:0014033]; neuron development [GO:0048666]; neuron differentiation [GO:0030182]; osteoblast differentiation [GO:0001649]; outflow tract morphogenesis [GO:0003151]; platelet formation [GO:0030220]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of behavioral fear response [GO:2000987]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cardiac muscle cell differentiation [GO:2000727]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of macrophage apoptotic process [GO:2000111]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of skeletal muscle cell differentiation [GO:2001016]; positive regulation of skeletal muscle tissue development [GO:0048643]; positive regulation of transcription by RNA polymerase II [GO:0045944]; primary heart field specification [GO:0003138]; regulation of germinal center formation [GO:0002634]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of synaptic activity [GO:0060025]; regulation of transcription by RNA polymerase II [GO:0006357]; renal tubule morphogenesis [GO:0061333]; secondary heart field specification [GO:0003139]; sinoatrial valve morphogenesis [GO:0003185]; skeletal muscle tissue development [GO:0007519]; smooth muscle cell differentiation [GO:0051145]; ventricular cardiac muscle cell differentiation [GO:0055012] GO:0000122; GO:0000165; GO:0000976; GO:0000977; GO:0000978; GO:0000981; GO:0001228; GO:0001568; GO:0001649; GO:0001782; GO:0001947; GO:0001958; GO:0001974; GO:0002062; GO:0002467; GO:0002634; GO:0003138; GO:0003139; GO:0003151; GO:0003185; GO:0003211; GO:0003677; GO:0003700; GO:0005634; GO:0005737; GO:0006357; GO:0006959; GO:0007507; GO:0007519; GO:0007521; GO:0007611; GO:0010628; GO:0010629; GO:0010694; GO:0014033; GO:0016528; GO:0016607; GO:0030182; GO:0030220; GO:0030279; GO:0030318; GO:0030501; GO:0030890; GO:0032991; GO:0035051; GO:0035984; GO:0042100; GO:0043524; GO:0045652; GO:0045663; GO:0045666; GO:0045669; GO:0045893; GO:0045944; GO:0046983; GO:0048643; GO:0048666; GO:0050853; GO:0051145; GO:0055012; GO:0060025; GO:0060045; GO:0061333; GO:0071222; GO:0071277; GO:0071374; GO:0071466; GO:0071498; GO:0071560; GO:0072102; GO:0072160; GO:2000111; GO:2000727; GO:2000987; GO:2001013; GO:2001016 27798 XM_044315580.1 24 11 6 5 1 NA NA NA NA NA NA 27799 XM_029347092.2 54 0 9 0 0 NA NA NA NA NA NA 27800 XR_006393427.1 6 8 6 9 83 NA NA NA NA NA NA 27801 XM_029350980.2 320 298 177 297 96 Q5U3N0 4.67e-118 Pleckstrin homology domain-containing family A member 8 (PH domain-containing family A member 8) Danio rerio (Zebrafish) (Brachydanio rerio) ceramide transport [GO:0035627]; ER to Golgi ceramide transport [GO:0035621]; intermembrane lipid transfer [GO:0120009]; protein transport [GO:0015031] GO:0005794; GO:0005829; GO:0015031; GO:0016020; GO:0035621; GO:0035627; GO:0120009; GO:1902387; GO:1902388 27802 XM_044324354.1 21 20 12 45 102 NA NA NA NA NA NA 27803 XM_029324687.2 233 61 118 162 60 NA NA NA NA NA NA 27804 XM_044326686.1 246 91 80 48 159 NA NA NA NA NA NA 27805 XM_044317664.1 136 24 0 0 182 NA NA NA NA NA NA 27806 XR_003824562.2 10 8 6 18 18 NA NA NA NA NA NA 27807 XM_044327802.1 145 38 154 332 176 Q3UQ28 3.3e-30 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 27808 XM_044327802.1 145 38 154 332 176 Q3UQ28 2.95e-27 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 27809 XM_044324060.1 97 0 73 60 0 NA NA NA NA NA NA 27810 XM_029341753.2 2164 638 1030 2654 2349 Q0P4P2 2.18e-62 Fibrinogen C domain-containing protein 1 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0008061; GO:0016020; GO:0046872 27811 XM_029326921.2 1533 1598 578 1331 1311 B9ENM6 6.03e-47 Ubiquitin-fold modifier 1 Salmo salar (Atlantic salmon) protein K69-linked ufmylation [GO:1990592]; protein ufmylation [GO:0071569]; response to endoplasmic reticulum stress [GO:0034976]; reticulophagy [GO:0061709] GO:0005634; GO:0005737; GO:0034976; GO:0061709; GO:0071569; GO:1990592 27812 XM_044307938.1 0 0 6 0 0 NA NA NA NA NA NA 27813 XM_044327651.1 4 0 2 17 0 NA NA NA NA NA NA 27814 XM_044311102.1 433 116 240 586 96 NA NA NA NA NA NA 27815 XM_044326095.1 0 3 4 9 2 NA NA NA NA NA NA 27816 XR_006394168.1 6 27 6 9 81 NA NA NA NA NA NA 27817 XM_029343803.2 195 191 144 279 166 NA NA NA NA NA NA 27818 XM_029343468.2 0 48 37 0 0 NA NA NA NA NA NA 27819 XM_044310037.1 218 65 110 39 58 P10079 1.33e-121 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 27820 XM_044310037.1 218 65 110 39 58 P10079 4.1e-115 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 27821 XM_044310037.1 218 65 110 39 58 P10079 2.1e-107 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 27822 XM_044310037.1 218 65 110 39 58 P10079 1.46e-57 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 27823 XM_029357580.2 0 0 0 60 0 Q8BTK5 6.42e-54 SET and MYND domain-containing protein 4 (EC 2.1.1.-) Mus musculus (Mouse) heart development [GO:0007507]; methylation [GO:0032259] GO:0005634; GO:0005737; GO:0007507; GO:0008168; GO:0032259; GO:0042826; GO:0046872 27824 XM_029324002.2 191 198 129 469 69 Q7TQA3 7.43e-102 Epidermal retinol dehydrogenase 2 (EPHD-2) (RDH-E2) (EC 1.1.1.105) (Retinal short-chain dehydrogenase reductase 2) (retSDR2) (Short-chain dehydrogenase reductase 9) (Short-chain dehydrogenase/reductase family 16C member 5) Mus musculus (Mouse) keratinocyte proliferation [GO:0043616]; negative regulation of histone acetylation [GO:0035067]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of histone deacetylation [GO:0031065]; retinal metabolic process [GO:0042574]; retinol metabolic process [GO:0042572] GO:0000122; GO:0000785; GO:0003714; GO:0004745; GO:0005634; GO:0005783; GO:0005789; GO:0005811; GO:0005886; GO:0016616; GO:0017053; GO:0031065; GO:0035067; GO:0042572; GO:0042574; GO:0043616; GO:0061629; GO:0140297 27825 XM_044311486.1 368 77 282 171 216 NA NA NA NA NA NA 27826 XR_003823238.2 7 3 1 13 62 NA NA NA NA NA NA 27827 XM_029330547.2 6 7 0 192 137 Q8R368 2.19e-89 Dynein axonemal assembly factor 4 (Dyslexia susceptibility 1 candidate gene 1 protein homolog) Mus musculus (Mouse) cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; heart development [GO:0007507]; inner dynein arm assembly [GO:0036159]; learning or memory [GO:0007611]; neuron migration [GO:0001764]; outer dynein arm assembly [GO:0036158]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of proteasomal protein catabolic process [GO:0061136] GO:0001764; GO:0003341; GO:0003351; GO:0005576; GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0005886; GO:0007368; GO:0007507; GO:0007611; GO:0030331; GO:0033146; GO:0036158; GO:0036159; GO:0043005; GO:0051649; GO:0061136; GO:0097730; GO:0120293 27828 XM_044321625.1 2 0 0 263 2 P49914 1.28e-65 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) (5,10-methenyl-tetrahydrofolate synthetase) (MTHFS) (Methenyl-THF synthetase) Homo sapiens (Human) folic acid catabolic process [GO:0046657]; folic acid metabolic process [GO:0046655]; folic acid-containing compound biosynthetic process [GO:0009396]; formate metabolic process [GO:0015942]; glutamate metabolic process [GO:0006536]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653] GO:0005524; GO:0005542; GO:0005737; GO:0005739; GO:0005759; GO:0005829; GO:0006536; GO:0009396; GO:0015942; GO:0030272; GO:0035999; GO:0046653; GO:0046655; GO:0046657; GO:0046872 27829 XM_044311734.1 67 41 7 16 81 Q9NVH0 1.16e-27 Exonuclease 3'-5' domain-containing protein 2 (EC 3.1.11.1) (3'-5' exoribonuclease EXD2) (EC 3.1.13.-) (Exonuclease 3'-5' domain-like-containing protein 2) Homo sapiens (Human) DNA double-strand break processing [GO:0000729]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; replication fork processing [GO:0031297] GO:0000175; GO:0000287; GO:0000724; GO:0000729; GO:0003676; GO:0005634; GO:0005737; GO:0005739; GO:0005741; GO:0005759; GO:0006302; GO:0008296; GO:0008310; GO:0008408; GO:0008852; GO:0030145; GO:0031297; GO:0042803; GO:0045111; GO:0090305; GO:0090734 27830 XR_006397906.1 94 88 63 82 147 NA NA NA NA NA NA 27831 XM_029326877.2 2186 1509 1228 1760 1781 Q86UW6 5.67e-50 NEDD4-binding protein 2 (N4BP2) (EC 3.-.-.-) (BCL-3-binding protein) Homo sapiens (Human) NA GO:0004519; GO:0004520; GO:0005524; GO:0005829; GO:0043130; GO:0046404 27832 XM_029326877.2 2186 1509 1228 1760 1781 Q86UW6 4.29e-39 NEDD4-binding protein 2 (N4BP2) (EC 3.-.-.-) (BCL-3-binding protein) Homo sapiens (Human) NA GO:0004519; GO:0004520; GO:0005524; GO:0005829; GO:0043130; GO:0046404 27833 XM_029346479.2 224 67 268 165 405 Q6DHC3 1.7e-88 Probable mitochondrial glutathione transporter SLC25A40 (Solute carrier family 25 member 40) Danio rerio (Zebrafish) (Brachydanio rerio) mitochondrial transmembrane transport [GO:1990542] GO:0005739; GO:0005743; GO:1990542 27834 XR_006394996.1 58 60 43 27 20 E7FAM5 1.07e-69 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 27835 XR_006394996.1 58 60 43 27 20 E7FAM5 1.07e-69 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 27836 XM_029353478.2 0 0 0 39 226 A0A3L7I2I8 9.21e-134 85/88 kDa calcium-independent phospholipase A2 (CaI-PLA2) (EC 3.1.1.4) (2-lysophosphatidylcholine acylhydrolase) (EC 3.1.1.5) (Group VI phospholipase A2) (GVI PLA2) (Intracellular membrane-associated calcium-independent phospholipase A2 beta) (iPLA2-beta) (PLA2G6) (Palmitoyl-CoA hydrolase) (EC 3.1.2.2) (Patatin-like phospholipase domain-containing protein 9) (PNPLA9) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) antibacterial humoral response [GO:0019731]; cardiolipin acyl-chain remodeling [GO:0035965]; cardiolipin biosynthetic process [GO:0032049]; phosphatidic acid metabolic process [GO:0046473]; phosphatidylcholine catabolic process [GO:0034638]; phosphatidylethanolamine catabolic process [GO:0046338]; platelet activating factor metabolic process [GO:0046469]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774] GO:0003847; GO:0004622; GO:0005615; GO:0005739; GO:0005829; GO:0005886; GO:0016290; GO:0017171; GO:0019731; GO:0031143; GO:0032049; GO:0034451; GO:0034638; GO:0035774; GO:0035965; GO:0042802; GO:0046338; GO:0046469; GO:0046473; GO:0047499; GO:0102545; GO:0102991 27837 XR_006397433.1 3 45 13 44 136 NA NA NA NA NA NA 27838 XR_003827164.2 67 55 29 19 12 NA NA NA NA NA NA 27839 XM_029340956.2 1575 1592 930 1035 1016 A2TLM1 2.64e-102 Ribose-5-phosphate isomerase (EC 5.3.1.6) (Phosphoriboisomerase) Sus scrofa (Pig) D-ribose metabolic process [GO:0006014]; pentose-phosphate shunt, non-oxidative branch [GO:0009052] GO:0004751; GO:0006014; GO:0009052; GO:0043231 27840 XM_029327531.2 49 53 59 31 20 NA NA NA NA NA NA 27841 XM_029337786.2 0 55 0 127 358 Q09299 1.17e-38 Putative RNA-binding protein EEED8.10 Caenorhabditis elegans SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0003723; GO:0019005; GO:0031146 27842 XM_044314576.1 758 75 165 119 322 O95497 2.57e-139 Pantetheinase (EC 3.5.1.92) (Pantetheine hydrolase) (Tiff66) (Vascular non-inflammatory molecule 1) (Vanin-1) Homo sapiens (Human) acute inflammatory response [GO:0002526]; cell-cell adhesion [GO:0098609]; chronic inflammatory response [GO:0002544]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; pantothenate metabolic process [GO:0015939]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of T cell differentiation in thymus [GO:0033089]; response to oxidative stress [GO:0006979] GO:0002526; GO:0002544; GO:0005576; GO:0005886; GO:0006954; GO:0006979; GO:0015939; GO:0016020; GO:0017159; GO:0033089; GO:0035577; GO:0045087; GO:0098609; GO:1902177 27843 XM_029327581.2 106 11 43 104 246 P0CT40 9.87e-90 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 27844 XM_044310505.1 19 44 35 1 74 O43854 7.98e-24 EGF-like repeat and discoidin I-like domain-containing protein 3 (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1) Homo sapiens (Human) cell adhesion [GO:0007155]; positive regulation of cell-substrate adhesion [GO:0010811] GO:0005178; GO:0005509; GO:0007155; GO:0010811; GO:0062023; GO:0070062; GO:1903561 27845 XM_044310505.1 19 44 35 1 74 O43854 1e-21 EGF-like repeat and discoidin I-like domain-containing protein 3 (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1) Homo sapiens (Human) cell adhesion [GO:0007155]; positive regulation of cell-substrate adhesion [GO:0010811] GO:0005178; GO:0005509; GO:0007155; GO:0010811; GO:0062023; GO:0070062; GO:1903561 27846 XM_044327816.1 809 334 75 438 805 NA NA NA NA NA NA 27847 XM_044325267.1 1351 1347 849 1292 1122 Q86VP6 0 Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (TBP-interacting protein of 120 kDa A) (TBP-interacting protein 120A) (p120 CAND1) Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of catalytic activity [GO:0043086]; positive regulation of RNA polymerase II transcription preinitiation complex assembly [GO:0045899]; protein ubiquitination [GO:0016567]; SCF complex assembly [GO:0010265] GO:0000151; GO:0005576; GO:0005634; GO:0005654; GO:0005737; GO:0005794; GO:0005829; GO:0010265; GO:0016020; GO:0016567; GO:0017025; GO:0030154; GO:0031461; GO:0034774; GO:0043086; GO:0045899; GO:0070062; GO:1904813 27848 XM_029325400.2 1115 551 375 881 1014 Q03237 1.3e-87 Myb-related protein B (B-Myb) (Myb-like protein 2) Gallus gallus (Chicken) mitotic cell cycle [GO:0000278]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355] GO:0000278; GO:0000978; GO:0000981; GO:0005634; GO:0006355; GO:0045944 27849 XM_044321285.1 162 25 0 0 0 NA NA NA NA NA NA 27850 XM_044319143.1 502 1 0 0 385 NA NA NA NA NA NA 27851 XM_044317876.1 0 0 0 11 4 NA NA NA NA NA NA 27852 XR_003824239.2 27 25 7 84 31 NA NA NA NA NA NA 27853 XM_029329293.2 223 157 197 218 332 NA NA NA NA NA NA 27854 XM_044326479.1 624 370 232 355 340 NA NA NA NA NA NA 27855 XR_006397748.1 12 5 21 0 65 NA NA NA NA NA NA 27856 XM_029349962.2 324 324 302 449 591 Q9D552 1.12e-72 Spermatogenesis-associated protein 17 (Spermatogenesis-related protein 11) Mus musculus (Mouse) NA GO:0005516; GO:0005737 27857 XM_044309842.1 8 10 33 12 28 NA NA NA NA NA NA 27858 XM_044325971.1 11 0 0 9 26 NA NA NA NA NA NA 27859 XM_044309292.1 0 0 27 1 35 NA NA NA NA NA NA 27860 XM_044314403.1 0 0 0 0 8 Q99436 2.01e-27 Proteasome subunit beta type-7 (EC 3.4.25.1) (Macropain chain Z) (Multicatalytic endopeptidase complex chain Z) (Proteasome subunit Z) Homo sapiens (Human) proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] GO:0000502; GO:0004175; GO:0004298; GO:0005576; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005839; GO:0010498; GO:0016604; GO:0019774; GO:0034774; GO:0043161; GO:1904813 27861 XM_044319016.1 305 234 150 277 121 Q09328 6.54e-146 Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (EC 2.4.1.155) (Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase V) (GlcNAc-T V) (GNT-V) (Mannoside acetylglucosaminyltransferase 5) (N-acetylglucosaminyl-transferase V) [Cleaved into: Secreted alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (Secreted beta-1,6-N-acetylglucosaminyltransferase V) (Secreted GNT-V)] Homo sapiens (Human) negative regulation of protein tyrosine phosphatase activity [GO:1903614]; positive regulation of cell migration [GO:0030335]; positive regulation of receptor signaling pathway via STAT [GO:1904894]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279]; viral protein processing [GO:0019082] GO:0000139; GO:0004864; GO:0005794; GO:0006487; GO:0016020; GO:0018279; GO:0019082; GO:0030144; GO:0030145; GO:0030335; GO:0070062; GO:1903614; GO:1904894 27862 XM_029337200.2 498 338 377 571 532 Q6PIF6 7.45e-70 Unconventional myosin-VIIb Homo sapiens (Human) actin filament organization [GO:0007015]; brush border assembly [GO:1904970]; cell differentiation [GO:0030154]; sensory organ development [GO:0007423]; sensory perception of sound [GO:0007605]; vesicle transport along actin filament [GO:0030050] GO:0000146; GO:0005524; GO:0005737; GO:0005902; GO:0005903; GO:0007015; GO:0007423; GO:0007605; GO:0015629; GO:0016459; GO:0030050; GO:0030154; GO:0031982; GO:0051015; GO:0090651; GO:1904970 27863 XM_029343638.2 55 13 46 68 39 NA NA NA NA NA NA 27864 XR_006397555.1 8 0 6 0 9 NA NA NA NA NA NA 27865 XM_029341660.2 266 157 170 228 429 Q0P6H9 2.65e-141 Transmembrane protein 62 Homo sapiens (Human) NA GO:0016020; GO:0016787 27866 XM_044325190.1 237 279 218 278 346 Q4V8X4 3.7e-59 Acyl-CoA-binding domain-containing protein 6 Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0000062; GO:0005737 27867 XM_029330240.2 154 110 254 419 287 O95163 0 Elongator complex protein 1 (ELP1) (IkappaB kinase complex-associated protein) (IKK complex-associated protein) (p150) Homo sapiens (Human) regulation of translation [GO:0006417]; tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation [GO:0002926]; tRNA wobble uridine modification [GO:0002098] GO:0000049; GO:0002098; GO:0002926; GO:0005634; GO:0005737; GO:0005829; GO:0006417; GO:0033588; GO:0043621 27868 XM_029325766.2 1226 789 336 658 563 Q5R5L7 3.35e-28 Arrestin domain-containing protein 3 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0005764; GO:0005769; GO:0005886 27869 XM_044312809.1 101 12 2 42 40 Q9HD40 0 O-phosphoseryl-tRNA(Sec) selenium transferase (EC 2.9.1.2) (Liver-pancreas antigen) (LP) (SLA-p35) (SLA/LP autoantigen) (Selenocysteine synthase) (Sec synthase) (Selenocysteinyl-tRNA(Sec) synthase) (Sep-tRNA:Sec-tRNA synthase) (SepSecS) (Soluble liver antigen) (SLA) (UGA suppressor tRNA-associated protein) (tRNA(Ser/Sec)-associated antigenic protein) Homo sapiens (Human) selenocysteine incorporation [GO:0001514]; selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056] GO:0000049; GO:0001514; GO:0005634; GO:0005737; GO:0005829; GO:0097056; GO:0098621 27870 XM_044307819.1 47 0 4 0 0 NA NA NA NA NA NA 27871 XM_044314390.1 85 54 33 183 94 NA NA NA NA NA NA 27872 XM_044306866.1 1182 502 749 1253 851 Q5TYV4 3.25e-68 Spermatogenesis-defective protein 39 homolog (hSPE-39) (VPS33B-interacting protein in apical-basolateral polarity regulator) (VPS33B-interacting protein in polarity and apical restriction) Danio rerio (Zebrafish) (Brachydanio rerio) cell differentiation [GO:0030154]; hepaticobiliary system development [GO:0061008]; intracellular protein transport [GO:0006886]; spermatogenesis [GO:0007283]; vacuolar transport [GO:0007034] GO:0005737; GO:0005769; GO:0005770; GO:0006886; GO:0007034; GO:0007283; GO:0030154; GO:0055037; GO:0061008 27873 XM_029355742.2 131 96 41 3 48 P24044 8.88e-48 Calmodulin Plasmodium falciparum NA GO:0005509; GO:0005737; GO:0020007 27874 XR_006393496.1 351 227 153 202 346 A6NNF4 1.4e-35 Zinc finger protein 726 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 27875 XR_006393496.1 351 227 153 202 346 A6NNF4 2.24e-32 Zinc finger protein 726 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 27876 XR_006393496.1 351 227 153 202 346 A6NNF4 1.09e-31 Zinc finger protein 726 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 27877 XR_006393496.1 351 227 153 202 346 A6NNF4 1.45e-31 Zinc finger protein 726 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 27878 XR_006393496.1 351 227 153 202 346 A6NNF4 2.68e-31 Zinc finger protein 726 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 27879 XR_006393496.1 351 227 153 202 346 A6NNF4 2.84e-30 Zinc finger protein 726 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 27880 XR_006393496.1 351 227 153 202 346 A6NNF4 9.48e-29 Zinc finger protein 726 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 27881 XR_006393496.1 351 227 153 202 346 A6NNF4 5.91e-24 Zinc finger protein 726 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 27882 XR_006393496.1 351 227 153 202 346 A6NNF4 1.3e-21 Zinc finger protein 726 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 27883 XR_006392978.1 41 2 25 5 151 NA NA NA NA NA NA 27884 XM_029351055.2 1639 1091 1121 1605 1997 Q92973 0 Transportin-1 (Importin beta-2) (Karyopherin beta-2) (M9 region interaction protein) (MIP) Homo sapiens (Human) protein import into nucleus [GO:0006606] GO:0003723; GO:0005634; GO:0005737; GO:0005829; GO:0005929; GO:0006606; GO:0008139; GO:0031267; GO:0061608; GO:0070062 27885 XM_029347052.2 95 0 0 107 310 Q63055 1.64e-81 ADP-ribosylation factor-related protein 1 (ARF-related protein 1) (ARP) Rattus norvegicus (Rat) gastrulation [GO:0007369]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; protein localization to Golgi apparatus [GO:0034067]; retrograde transport, endosome to Golgi [GO:0042147] GO:0003924; GO:0005525; GO:0005794; GO:0005802; GO:0005829; GO:0006886; GO:0007369; GO:0016020; GO:0034067; GO:0042147; GO:0043001 27886 XM_029337512.2 5465 9703 6049 8672 6347 Q6DK98 1.72e-77 Nuclear distribution protein nudE-like 1-A Xenopus laevis (African clawed frog) lysosome localization [GO:0032418]; positive regulation of ruffle assembly [GO:1900029] GO:0005737; GO:0005815; GO:0005819; GO:0005874; GO:0008017; GO:0032418; GO:1900029 27887 XM_029356501.2 106 47 0 396 0 P52275 0 Tubulin beta-2 chain (Beta-2-tubulin) Caenorhabditis elegans meiotic spindle organization [GO:0000212]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278] GO:0000212; GO:0000226; GO:0000278; GO:0003924; GO:0005200; GO:0005525; GO:0005737; GO:0005874; GO:0005876; GO:0045298; GO:0046872 27888 XR_006395632.1 35 111 45 59 68 NA NA NA NA NA NA 27889 XM_044313593.1 6 0 0 0 0 Q94K49 1.23e-28 Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1 (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) epigenetic regulation of gene expression [GO:0040029] GO:0003682; GO:0004518; GO:0005634; GO:0035098; GO:0035102; GO:0040029; GO:0046872 27890 XM_029335051.2 10 0 0 3 1 NA NA NA NA NA NA 27891 XM_029327089.2 251 103 114 127 207 Q9UKP5 8.05e-98 A disintegrin and metalloproteinase with thrombospondin motifs 6 (ADAM-TS 6) (ADAM-TS6) (ADAMTS-6) (EC 3.4.24.-) Homo sapiens (Human) aorta development [GO:0035904]; cardiac septum development [GO:0003279]; coronary vasculature development [GO:0060976]; extracellular matrix organization [GO:0030198]; kidney development [GO:0001822]; proteolysis [GO:0006508] GO:0001822; GO:0003279; GO:0004222; GO:0005576; GO:0006508; GO:0008237; GO:0030198; GO:0031012; GO:0035904; GO:0046872; GO:0060976 27892 XM_029346419.2 234 226 270 306 282 Q16822 0 Phosphoenolpyruvate carboxykinase [GTP], mitochondrial (PEPCK-M) (EC 4.1.1.32) Homo sapiens (Human) cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glycerol biosynthetic process from pyruvate [GO:0046327]; hepatocyte differentiation [GO:0070365]; NADH oxidation [GO:0006116]; oxaloacetate metabolic process [GO:0006107]; positive regulation of insulin secretion [GO:0032024]; propionate catabolic process [GO:0019543]; response to lipid [GO:0033993]; response to lipopolysaccharide [GO:0032496]; response to starvation [GO:0042594] GO:0004611; GO:0004613; GO:0005525; GO:0005739; GO:0005759; GO:0005829; GO:0006094; GO:0006107; GO:0006116; GO:0019543; GO:0030145; GO:0032024; GO:0032496; GO:0032869; GO:0033993; GO:0042594; GO:0046327; GO:0070365; GO:0071333; GO:0071356; GO:0071549 27893 XM_044307994.1 0 0 10 0 19 NA NA NA NA NA NA 27894 XM_044315477.1 458 256 312 62 176 Q96AY4 7.91e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27895 XM_029347978.2 1292 1110 594 1165 1328 O88544 0 COP9 signalosome complex subunit 4 (SGN4) (Signalosome subunit 4) (JAB1-containing signalosome subunit 4) Mus musculus (Mouse) protein deneddylation [GO:0000338] GO:0000338; GO:0005634; GO:0005737; GO:0008021; GO:0008180; GO:0016607; GO:0030054 27896 XM_029342911.2 1030 663 780 703 1096 Q16U49 0 Mediator of RNA polymerase II transcription subunit 14 (Mediator complex subunit 14) Aedes aegypti (Yellowfever mosquito) (Culex aegypti) regulation of transcription by RNA polymerase II [GO:0006357] GO:0003712; GO:0006357; GO:0016592 27897 XR_006396703.1 1376 832 854 1555 1327 NA NA NA NA NA NA 27898 XM_044316385.1 4 10 13 42 12 NA NA NA NA NA NA 27899 XM_029357072.2 8 2 120 6 136 NA NA NA NA NA NA 27900 XM_044327763.1 157 79 44 61 56 NA NA NA NA NA NA 27901 XM_029335070.2 422 93 69 199 102 NA NA NA NA NA NA 27902 XM_029347713.2 223 582 202 257 381 NA NA NA NA NA NA 27903 XM_029345172.2 241 246 147 249 292 A7RS11 2.98e-121 Histone PARylation factor 1 Nematostella vectensis (Starlet sea anemone) cellular response to DNA damage stimulus [GO:0006974]; regulation of protein ADP-ribosylation [GO:0010835] GO:0005634; GO:0005694; GO:0006974; GO:0010835; GO:0042393; GO:0072572 27904 XM_029343378.2 64 32 4 109 19 NA NA NA NA NA NA 27905 XM_044324159.1 121 39 13 18 139 P0CT39 1.13e-79 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 27906 XM_044308910.1 197 0 0 5 98 NA NA NA NA NA NA 27907 XM_044321346.1 90 112 53 0 2 NA NA NA NA NA NA 27908 XM_044311107.1 0 0 0 5 7 NA NA NA NA NA NA 27909 XM_044317050.1 79 56 0 0 38 Q96D71 1.14e-25 RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1) Homo sapiens (Human) endocytosis [GO:0006897]; endosomal transport [GO:0016197] GO:0005509; GO:0005829; GO:0005886; GO:0005905; GO:0006897; GO:0016197; GO:0017124 27910 XM_029356313.2 80 49 110 89 160 Q6DFB7 1.48e-55 Centrosomal protein POC5 (Protein of centriole 5) Xenopus laevis (African clawed frog) cell cycle [GO:0007049] GO:0005737; GO:0005814; GO:0007049 27911 XM_029344198.2 1612 1049 855 1322 1020 NA NA NA NA NA NA 27912 XR_003823474.1 0 0 6 0 0 NA NA NA NA NA NA 27913 XM_029358067.2 1113 826 634 928 930 Q5ZKY2 0 Ubiquitin-like modifier-activating enzyme ATG7 (ATG12-activating enzyme E1 ATG7) (Autophagy-related protein 7) (APG7-like) Gallus gallus (Chicken) autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; C-terminal protein lipidation [GO:0006501]; cellular response to nitrogen starvation [GO:0006995]; late nucleophagy [GO:0044805]; piecemeal microautophagy of the nucleus [GO:0034727]; protein modification by small protein conjugation [GO:0032446]; protein transport [GO:0015031]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511] GO:0000045; GO:0000407; GO:0000422; GO:0005737; GO:0006501; GO:0006914; GO:0006995; GO:0015031; GO:0019778; GO:0019779; GO:0032446; GO:0034727; GO:0042752; GO:0044805; GO:0048511 27914 XM_044329039.1 0 0 0 0 83 Q8IUH5 0 Palmitoyltransferase ZDHHC17 (EC 2.3.1.225) (Acyltransferase ZDHHC17) (EC 2.3.1.-) (DHHC domain-containing cysteine-rich protein 17) (DHHC17) (Huntingtin yeast partner H) (Huntingtin-interacting protein 14) (HIP-14) (Huntingtin-interacting protein 3) (HIP-3) (Huntingtin-interacting protein H) (Putative MAPK-activating protein PM11) (Putative NF-kappa-B-activating protein 205) (Zinc finger DHHC domain-containing protein 17) Homo sapiens (Human) axonogenesis [GO:0007409]; lipoprotein transport [GO:0042953]; peptidyl-L-cysteine S-palmitoylation [GO:0018230]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein palmitoylation [GO:0018345]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of neurotrophin TRK receptor signaling pathway [GO:0051386] GO:0000139; GO:0005102; GO:0005794; GO:0007409; GO:0016235; GO:0016409; GO:0018230; GO:0018345; GO:0019705; GO:0019706; GO:0030660; GO:0042734; GO:0042802; GO:0042953; GO:0042995; GO:0043123; GO:0043231; GO:0051386; GO:0070372; GO:0140439 27915 XM_044318024.1 221 107 107 143 363 NA NA NA NA NA NA 27916 XM_044326831.1 45 49 0 103 33 Q16445 2.62e-68 Gamma-aminobutyric acid receptor subunit alpha-6 (GABA(A) receptor subunit alpha-6) Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid signaling pathway [GO:0007214]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; regulation of postsynaptic membrane potential [GO:0060078]; signal transduction [GO:0007165]; synaptic transmission, GABAergic [GO:0051932] GO:0004890; GO:0005231; GO:0005237; GO:0005886; GO:0007165; GO:0007214; GO:0007268; GO:0008503; GO:0022851; GO:0030594; GO:0032590; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051932; GO:0060078; GO:0098794; GO:0099192; GO:1902476; GO:1902711; GO:1904315 27917 XM_029340369.2 255 147 200 262 222 P41245 2.44e-21 Matrix metalloproteinase-9 (MMP-9) (EC 3.4.24.35) (92 kDa gelatinase) (92 kDa type IV collagenase) (Gelatinase B) (GELB) Mus musculus (Mouse) aging [GO:0007568]; apoptotic process [GO:0006915]; cell migration [GO:0016477]; cellular response to cadmium ion [GO:0071276]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV-A [GO:0071492]; collagen catabolic process [GO:0030574]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; heart development [GO:0007507]; macrophage chemotaxis [GO:0048246]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of vascular associated smooth muscle cell proliferation [GO:1904707]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]; response to oxidative stress [GO:0006979]; response to xenobiotic stimulus [GO:0009410]; skeletal system development [GO:0001501]; tissue remodeling [GO:0048771] GO:0001501; GO:0001934; GO:0001968; GO:0002687; GO:0004175; GO:0004222; GO:0004252; GO:0005615; GO:0006508; GO:0006915; GO:0006979; GO:0007507; GO:0007566; GO:0007568; GO:0008233; GO:0008237; GO:0008270; GO:0009410; GO:0016477; GO:0030163; GO:0030198; GO:0030574; GO:0031915; GO:0032991; GO:0034614; GO:0035987; GO:0042802; GO:0043065; GO:0043066; GO:0043388; GO:0044877; GO:0045742; GO:0045766; GO:0048147; GO:0048246; GO:0048771; GO:0051549; GO:0062023; GO:0071276; GO:0071460; GO:0071492; GO:0090200; GO:1900122; GO:1904645; GO:1904707; GO:2000697; GO:2001243; GO:2001258; GO:2001268 27918 XM_044323306.1 67 0 1 0 0 NA NA NA NA NA NA 27919 XM_029355887.2 258 125 98 349 339 NA NA NA NA NA NA 27920 XR_006391803.1 0 0 0 0 20 NA NA NA NA NA NA 27921 XM_044321306.1 106 52 27 31 131 P79218 1.99e-22 Substance-K receptor (SKR) (NK-2 receptor) (NK-2R) (Neurokinin A receptor) (Tachykinin receptor 2) Oryctolagus cuniculus (Rabbit) positive regulation of flagellated sperm motility [GO:1902093]; regulation of uterine smooth muscle contraction [GO:0070472] GO:0004995; GO:0005886; GO:0061827; GO:0070472; GO:0097225; GO:1902093 27922 XM_044313569.1 40 58 84 28 36 Q3SZK1 4.7e-118 Angio-associated migratory cell protein Bos taurus (Bovine) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; positive regulation of angiogenesis [GO:0045766]; positive regulation of endothelial cell migration [GO:0010595]; smooth muscle cell migration [GO:0014909] GO:0001525; GO:0005829; GO:0005886; GO:0008201; GO:0009986; GO:0010595; GO:0014909; GO:0015630; GO:0030154; GO:0045171; GO:0045766 27923 XM_044312098.1 643 412 376 666 390 NA NA NA NA NA NA 27924 XM_029336496.2 6967 10048 5481 7953 7061 Q5RDG4 4.67e-158 Protein disulfide-isomerase A3 (EC 5.3.4.1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003756; GO:0005783; GO:0005788; GO:0042470 27925 XM_029327252.2 485 458 383 587 264 Q810N6 5.38e-43 Ankyrin repeat domain-containing protein 45 Mus musculus (Mouse) cell population proliferation [GO:0008283] GO:0005737; GO:0008283; GO:0030496; GO:0032154; GO:0090543 27926 XM_044321588.1 13 14 5 17 10 NA NA NA NA NA NA 27927 XM_029355764.2 56 42 40 78 17 R1CW23 3.84e-95 Dimethylsulfonioproprionate lyase 7 (DMSP lyase 7) (EC 4.4.1.3) (Dimethylpropiothetin dethiomethylase 7) Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi) NA GO:0047869 27928 XM_029340828.2 529 270 144 379 303 Q5HZL5 1.89e-31 Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase A (EC 2.4.1.206) (Lactotriaosylceramide synthase A) (Lc(3)Cer synthase A) (Lc3 synthase A) (UDP-GlcNAc:beta-Gal beta-1,3-N-acetylglucosaminyltransferase 5A) (BGnT-5A) (Beta-1,3-Gn-T5A) (Beta-1,3-N-acetylglucosaminyltransferase 5A) (Beta3Gn-T5A) Xenopus laevis (African clawed frog) protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0008457; GO:0047256 27929 XM_044309726.1 0 0 0 12 0 NA NA NA NA NA NA 27930 XR_006395935.1 1 3 23 11 57 NA NA NA NA NA NA 27931 XM_044312160.1 0 0 0 0 11 NA NA NA NA NA NA 27932 XM_029346325.2 0 0 0 0 7 O00305 2e-63 Voltage-dependent L-type calcium channel subunit beta-4 (CAB4) (Calcium channel voltage-dependent subunit beta 4) Homo sapiens (Human) adult walking behavior [GO:0007628]; cAMP metabolic process [GO:0046058]; cellular response to leukemia inhibitory factor [GO:1990830]; chemical synaptic transmission [GO:0007268]; detection of light stimulus involved in visual perception [GO:0050908]; gamma-aminobutyric acid secretion [GO:0014051]; gamma-aminobutyric acid signaling pathway [GO:0007214]; muscle cell development [GO:0055001]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; neuromuscular junction development [GO:0007528]; neuronal action potential propagation [GO:0019227]; Peyer's patch development [GO:0048541]; positive regulation of protein localization to nucleolus [GO:1904751]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; regulation of synaptic vesicle exocytosis [GO:2000300]; regulation of voltage-gated calcium channel activity [GO:1901385]; spleen development [GO:0048536]; synaptic transmission, glutamatergic [GO:0035249]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538] GO:0005730; GO:0005829; GO:0005886; GO:0005891; GO:0007214; GO:0007268; GO:0007528; GO:0007628; GO:0008285; GO:0009898; GO:0014051; GO:0016607; GO:0019227; GO:0019901; GO:0035249; GO:0045202; GO:0046058; GO:0048536; GO:0048538; GO:0048541; GO:0050852; GO:0050908; GO:0055001; GO:0098793; GO:0098978; GO:0099626; GO:1901385; GO:1901387; GO:1904751; GO:1990830; GO:2000134; GO:2000300 27933 XM_029328773.2 56 0 54 59 0 Q5ZKJ5 4.94e-53 Transmembrane protein 180 (Major facilitator superfamily domain-containing 13A) Gallus gallus (Chicken) NA GO:0016020 27934 XM_029345805.2 185 289 293 408 0 NA NA NA NA NA NA 27935 XM_029356094.2 0 3 14 11 28 NA NA NA NA NA NA 27936 XM_044314631.1 170 19 82 245 188 NA NA NA NA NA NA 27937 XM_029330163.2 158 24 0 0 60 Q1LWH4 0 Fanconi-associated nuclease 1 (EC 3.1.21.-) (EC 3.1.4.1) (FANCD2/FANCI-associated nuclease 1) (Myotubularin-related protein 15) Danio rerio (Zebrafish) (Brachydanio rerio) DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; interstrand cross-link repair [GO:0036297]; nucleotide-excision repair [GO:0006289] GO:0000724; GO:0004528; GO:0005634; GO:0006281; GO:0006289; GO:0008409; GO:0017108; GO:0036297; GO:0046872; GO:0070336; GO:0140036 27938 XM_029338952.2 1476 1098 567 1031 1097 Q62559 0 Intraflagellar transport protein 52 homolog (Protein NGD5) Mus musculus (Mouse) cilium assembly [GO:0060271]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; heart looping [GO:0001947]; intraciliary anterograde transport [GO:0035720]; intraciliary transport [GO:0042073]; keratinocyte proliferation [GO:0043616]; negative regulation of keratinocyte proliferation [GO:0010839]; neural tube formation [GO:0001841]; non-motile cilium assembly [GO:1905515]; regulation of protein processing [GO:0070613]; smoothened signaling pathway [GO:0007224] GO:0001841; GO:0001947; GO:0005813; GO:0005814; GO:0005929; GO:0007224; GO:0007368; GO:0009953; GO:0010839; GO:0030992; GO:0032391; GO:0035720; GO:0036064; GO:0042073; GO:0042733; GO:0043616; GO:0044292; GO:0060271; GO:0070613; GO:0097542; GO:0097546; GO:0097733; GO:1905515 27939 XM_044311947.1 9 0 0 0 0 NA NA NA NA NA NA 27940 XM_044318397.1 27 0 0 5 65 NA NA NA NA NA NA 27941 XR_006392357.1 155 71 82 67 135 NA NA NA NA NA NA 27942 XM_044307858.1 0 40 0 42 35 NA NA NA NA NA NA 27943 XM_029344189.2 2219 1642 910 1422 1318 NA NA NA NA NA NA 27944 XM_044327740.1 7 9 3 5 22 NA NA NA NA NA NA 27945 XM_044322165.1 1002 667 561 954 557 Q9Y6Y1 6.4e-60 Calmodulin-binding transcription activator 1 Homo sapiens (Human) neuromuscular process controlling balance [GO:0050885]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0003690; GO:0003712; GO:0005634; GO:0005730; GO:0005829; GO:0006357; GO:0035307; GO:0043565; GO:0045944; GO:0050885; GO:0070886 27946 XM_044322165.1 1002 667 561 954 557 Q9Y6Y1 1.54e-45 Calmodulin-binding transcription activator 1 Homo sapiens (Human) neuromuscular process controlling balance [GO:0050885]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0003690; GO:0003712; GO:0005634; GO:0005730; GO:0005829; GO:0006357; GO:0035307; GO:0043565; GO:0045944; GO:0050885; GO:0070886 27947 XM_044327072.1 12 0 0 1 40 NA NA NA NA NA NA 27948 XR_006391833.1 15 3 42 4 24 NA NA NA NA NA NA 27949 XM_044320529.1 949 1664 687 1955 1314 NA NA NA NA NA NA 27950 XR_003825180.2 12 4 0 1 81 NA NA NA NA NA NA 27951 XM_029329325.2 1460 1934 1046 1178 794 A7SM54 2.76e-110 Ubiquitin-fold modifier-conjugating enzyme 1 (Ufm1-conjugating enzyme 1) Nematostella vectensis (Starlet sea anemone) protein K69-linked ufmylation [GO:1990592] GO:0061657; GO:0071568; GO:1990592 27952 XM_029323998.2 53 86 156 69 66 Q27433 5.91e-121 Mechanosensory protein 2 Caenorhabditis elegans detection of mechanical stimulus involved in sensory perception of touch [GO:0050976]; mechanosensory behavior [GO:0007638]; positive regulation of detection of mechanical stimulus involved in sensory perception of touch [GO:1905789]; positive regulation of mechanosensory behavior [GO:1905792]; potassium ion transport [GO:0006813]; response to mechanical stimulus [GO:0009612] GO:0005272; GO:0005886; GO:0006813; GO:0007638; GO:0009612; GO:0015485; GO:0032589; GO:0043005; GO:0050976; GO:1905789; GO:1905792 27953 XM_044309667.1 392 237 143 509 390 O16025 0 Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (AOS) (EC 4.2.1.-) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)] Plexaura homomalla (Black sea rod) arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; lipid oxidation [GO:0034440]; oxylipin biosynthetic process [GO:0031408] GO:0005506; GO:0005737; GO:0006633; GO:0009978; GO:0016020; GO:0019369; GO:0020037; GO:0031408; GO:0034440; GO:0047677 27954 XM_044307757.1 653 658 408 567 487 P30520 0 Adenylosuccinate synthetase isozyme 2 (AMPSase 2) (AdSS 2) (EC 6.3.4.4) (Adenylosuccinate synthetase, acidic isozyme) (Adenylosuccinate synthetase, liver isozyme) (L-type adenylosuccinate synthetase) (IMP--aspartate ligase 2) Homo sapiens (Human) 'de novo' AMP biosynthetic process [GO:0044208]; AMP biosynthetic process [GO:0006167]; aspartate metabolic process [GO:0006531]; cellular response to electrical stimulus [GO:0071257]; immune system process [GO:0002376]; IMP metabolic process [GO:0046040]; response to ammonium ion [GO:0060359]; response to purine-containing compound [GO:0014074] GO:0000287; GO:0002376; GO:0004019; GO:0005525; GO:0005737; GO:0005739; GO:0005829; GO:0006167; GO:0006531; GO:0014074; GO:0042301; GO:0044208; GO:0046040; GO:0060359; GO:0070062; GO:0071257 27955 XM_029345754.2 284 0 0 194 199 Q91035 1.01e-93 Sonic hedgehog protein (SHH) (EC 3.1.-.-) (Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains) (ShhNC) [Cleaved into: Sonic hedgehog protein N-product (ShhN) (Shh N-terminal processed signaling domains) (ShhNp)] Gallus gallus (Chicken) anterior/posterior pattern specification [GO:0009952]; apoptotic signaling pathway [GO:0097190]; cell fate determination [GO:0001709]; cell fate specification involved in pattern specification [GO:0060573]; cell-cell signaling [GO:0007267]; chondroblast differentiation [GO:0060591]; commissural neuron axon guidance [GO:0071679]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; fibroblast growth factor production [GO:0090269]; floor plate formation [GO:0021508]; growth plate cartilage chondrocyte growth [GO:0003430]; homeostasis of number of retina cells [GO:0048877]; intein-mediated protein splicing [GO:0016539]; negative regulation of apoptotic process [GO:0043066]; negative regulation of BMP signaling pathway [GO:0030514]; optic cup formation involved in camera-type eye development [GO:0003408]; optic nerve morphogenesis [GO:0021631]; polarity specification of anterior/posterior axis [GO:0009949]; polarity specification of dorsal/ventral axis [GO:0009951]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of cell morphogenesis involved in differentiation [GO:0010770]; positive regulation of gene expression [GO:0010628]; positive regulation of neural retina development [GO:0061075]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of smoothened signaling pathway [GO:0045880]; protein autoprocessing [GO:0016540]; proteoglycan biosynthetic process [GO:0030166]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; regulation of cell differentiation involved in tissue homeostasis [GO:0060786]; regulation of gene expression [GO:0010468]; regulation of neural precursor cell proliferation [GO:2000177]; response to retinoic acid [GO:0032526]; retina homeostasis [GO:0001895]; retinal pigment epithelium development [GO:0003406]; self proteolysis [GO:0097264]; signaling [GO:0023052]; spinal cord dorsal/ventral patterning [GO:0021513]; tissue development [GO:0009888] GO:0000139; GO:0001709; GO:0001895; GO:0003406; GO:0003408; GO:0003430; GO:0005509; GO:0005576; GO:0005615; GO:0005783; GO:0005789; GO:0005794; GO:0005886; GO:0007267; GO:0008233; GO:0008270; GO:0009880; GO:0009888; GO:0009949; GO:0009951; GO:0009952; GO:0010468; GO:0010628; GO:0010694; GO:0010770; GO:0016015; GO:0016539; GO:0016540; GO:0021508; GO:0021513; GO:0021631; GO:0023052; GO:0030166; GO:0030326; GO:0030514; GO:0032526; GO:0042733; GO:0043066; GO:0045669; GO:0045880; GO:0048877; GO:0060059; GO:0060573; GO:0060591; GO:0060785; GO:0060786; GO:0061075; GO:0071679; GO:0090269; GO:0097190; GO:0097264; GO:0140853; GO:2000177 27956 XM_044308543.1 36 15 39 12 29 E7FAM5 4e-57 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 27957 XM_029351901.2 3630 2943 3544 6661 5923 O00571 0 ATP-dependent RNA helicase DDX3X (EC 3.6.4.13) (CAP-Rf) (DEAD box protein 3, X-chromosomal) (DEAD box, X isoform) (DBX) (Helicase-like protein 2) (HLP2) Homo sapiens (Human) cell differentiation [GO:0030154]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to osmotic stress [GO:0071470]; cellular response to virus [GO:0098586]; chromosome segregation [GO:0007059]; cytosolic ribosome assembly [GO:0042256]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; gamete generation [GO:0007276]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway [GO:0097193]; lipid homeostasis [GO:0055088]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of translation [GO:0017148]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of chemokine (C-C motif) ligand 5 production [GO:0071651]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NLRP3 inflammasome complex assembly [GO:1900227]; positive regulation of protein acetylation [GO:1901985]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 7 signaling pathway [GO:0034157]; positive regulation of toll-like receptor 8 signaling pathway [GO:0034161]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translation [GO:0045727]; positive regulation of translation in response to endoplasmic reticulum stress [GO:0036493]; positive regulation of translational initiation [GO:0045948]; positive regulation of viral genome replication [GO:0045070]; primary miRNA processing [GO:0031053]; protein localization to cytoplasmic stress granule [GO:1903608]; response to virus [GO:0009615]; RNA secondary structure unwinding [GO:0010501]; stress granule assembly [GO:0034063]; translational initiation [GO:0006413]; Wnt signaling pathway [GO:0016055] GO:0003677; GO:0003678; GO:0003723; GO:0003724; GO:0003729; GO:0003924; GO:0005524; GO:0005576; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0005829; GO:0005886; GO:0006413; GO:0007059; GO:0007276; GO:0008134; GO:0008143; GO:0008190; GO:0008625; GO:0009615; GO:0010494; GO:0010501; GO:0010628; GO:0016055; GO:0016887; GO:0017111; GO:0017148; GO:0030027; GO:0030154; GO:0030307; GO:0030308; GO:0031053; GO:0031252; GO:0031333; GO:0031369; GO:0031954; GO:0032727; GO:0032728; GO:0033592; GO:0034063; GO:0034157; GO:0034161; GO:0034774; GO:0035556; GO:0035613; GO:0036493; GO:0042256; GO:0043015; GO:0043024; GO:0043065; GO:0043066; GO:0043154; GO:0043186; GO:0043273; GO:0043280; GO:0043539; GO:0045070; GO:0045087; GO:0045296; GO:0045727; GO:0045944; GO:0045948; GO:0048027; GO:0055088; GO:0070062; GO:0070878; GO:0071243; GO:0071470; GO:0071651; GO:0071902; GO:0072559; GO:0090263; GO:0097193; GO:0098586; GO:1900087; GO:1900227; GO:1901223; GO:1901224; GO:1901985; GO:1902042; GO:1902523; GO:1903608; GO:1904813; GO:2001243 27958 XM_029348123.2 188 39 108 144 504 NA NA NA NA NA NA 27959 XM_044313814.1 0 13 7 0 0 Q15485 1.21e-78 Ficolin-2 (37 kDa elastin-binding protein) (Collagen/fibrinogen domain-containing protein 2) (EBP-37) (Ficolin-B) (Ficolin-beta) (Hucolin) (L-ficolin) (Serum lectin p35) Homo sapiens (Human) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; positive regulation of opsonization [GO:1903028]; proteolysis [GO:0006508]; recognition of apoptotic cell [GO:0043654] GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005576; GO:0005581; GO:0005615; GO:0006508; GO:0008228; GO:0009897; GO:0042802; GO:0043394; GO:0043654; GO:0046872; GO:0048306; GO:0050829; GO:0050830; GO:0062023; GO:0070062; GO:0072562; GO:0097367; GO:1903028; GO:1905370; GO:2001065 27960 XR_006396784.1 51 444 732 274 193 NA NA NA NA NA NA 27961 XR_006393723.1 28 0 0 0 14 NA NA NA NA NA NA 27962 XM_044316249.1 184 370 77 221 496 O75897 4.68e-52 Sulfotransferase 1C4 (ST1C4) (EC 2.8.2.1) (Sulfotransferase 1C2) (SULT1C#2) Homo sapiens (Human) 3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; doxorubicin metabolic process [GO:0044598]; ethanol catabolic process [GO:0006068]; flavonoid metabolic process [GO:0009812]; sulfation [GO:0051923]; xenobiotic metabolic process [GO:0006805] GO:0004062; GO:0005737; GO:0005829; GO:0006068; GO:0006805; GO:0008146; GO:0009812; GO:0044598; GO:0050427; GO:0051923 27963 XM_044307987.1 133 36 75 66 106 NA NA NA NA NA NA 27964 XM_044323005.1 1451 629 779 1505 1548 O70595 0 ATP-binding cassette sub-family B member 6 (ABC-type heme transporter ABCB6) (EC 7.6.2.5) (Ubiquitously-expressed mammalian ABC half transporter) Rattus norvegicus (Rat) brain development [GO:0007420]; cellular copper ion homeostasis [GO:0006878]; cellular detoxification of cadmium ion [GO:0098849]; heme metabolic process [GO:0042168]; heme transmembrane transport [GO:0035351]; heme transport [GO:0015886]; melanosome assembly [GO:1903232]; porphyrin-containing compound biosynthetic process [GO:0006779]; porphyrin-containing compound metabolic process [GO:0006778]; skin development [GO:0043588]; tetrapyrrole metabolic process [GO:0033013]; transmembrane transport [GO:0055085] GO:0000139; GO:0005524; GO:0005654; GO:0005739; GO:0005740; GO:0005741; GO:0005765; GO:0005768; GO:0005774; GO:0005783; GO:0005789; GO:0005794; GO:0005829; GO:0005886; GO:0006778; GO:0006779; GO:0006878; GO:0007420; GO:0015439; GO:0015562; GO:0015886; GO:0016020; GO:0016887; GO:0020037; GO:0031901; GO:0031902; GO:0032585; GO:0033013; GO:0033162; GO:0035351; GO:0036020; GO:0042168; GO:0042626; GO:0043588; GO:0046906; GO:0055085; GO:0070062; GO:0098849; GO:0140359; GO:1903232 27965 XR_003823973.2 310 161 115 272 234 NA NA NA NA NA NA 27966 XM_044308552.1 121 335 137 99 193 NA NA NA NA NA NA 27967 XR_006391950.1 0 0 0 6 9 NA NA NA NA NA NA 27968 XM_029340543.2 1066 1314 516 946 252 Q59990 1.76e-28 Putative cytochrome P450 120 (EC 1.14.-.-) Synechocystis sp. (strain PCC 6803 / Kazusa) sterol metabolic process [GO:0016125] GO:0004497; GO:0005506; GO:0016125; GO:0016491; GO:0016705; GO:0020037 27969 XR_006391524.1 93 42 70 11 68 NA NA NA NA NA NA 27970 XM_029330497.2 72 21 82 36 101 NA NA NA NA NA NA 27971 XR_006396576.1 60 0 0 0 0 NA NA NA NA NA NA 27972 XM_029326853.2 81 22 16 36 24 Q9H9S5 7.27e-141 Ribitol 5-phosphate transferase FKRP (EC 2.7.8.-) (Fukutin-related protein) (Ribitol-5-phosphate transferase) Homo sapiens (Human) protein O-linked mannosylation [GO:0035269]; protein processing [GO:0016485]; protein tetramerization [GO:0051262] GO:0000139; GO:0002162; GO:0005615; GO:0005654; GO:0005791; GO:0005794; GO:0005829; GO:0016485; GO:0016780; GO:0035269; GO:0042383; GO:0042802; GO:0046872; GO:0051262 27973 XR_006395999.1 4 46 0 31 27 NA NA NA NA NA NA 27974 XM_029337963.2 0 0 32 0 79 NA NA NA NA NA NA 27975 XM_029325594.2 51 306 91 59 194 Q0V8T4 3.11e-31 Contactin-associated protein like 5-3 (Cell recognition molecule Caspr5-3) (Cell recognition molecule Caspr5c) (Contactin-associated protein-like 5c) Rattus norvegicus (Rat) cell adhesion [GO:0007155] GO:0005509; GO:0007155; GO:0016020 27976 XR_006392884.1 41 2 25 5 151 NA NA NA NA NA NA 27977 XM_029331590.2 297 335 323 590 298 NA NA NA NA NA NA 27978 XR_006393005.1 41 2 25 5 151 NA NA NA NA NA NA 27979 XR_006392828.1 24 18 30 75 25 P53454 1.32e-24 D(5)-like dopamine receptor Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) regulation of biological quality [GO:0065008] GO:0004930; GO:0005886; GO:0065008 27980 XM_044328931.1 28 11 15 10 21 Q9Y4F3 1.52e-139 Meiosis regulator and mRNA stability factor 1 (Limkain-b1) (Meiosis arrest female protein 1) Homo sapiens (Human) double-strand break repair [GO:0006302]; female meiotic nuclear division [GO:0007143]; oogenesis [GO:0048477]; regulation of gene expression [GO:0010468] GO:0004540; GO:0005737; GO:0005777; GO:0005794; GO:0006302; GO:0007143; GO:0010468; GO:0016020; GO:0043231; GO:0048477; GO:1903231; GO:1905762 27981 XM_044328931.1 28 11 15 10 21 Q9Y4F3 9.17e-36 Meiosis regulator and mRNA stability factor 1 (Limkain-b1) (Meiosis arrest female protein 1) Homo sapiens (Human) double-strand break repair [GO:0006302]; female meiotic nuclear division [GO:0007143]; oogenesis [GO:0048477]; regulation of gene expression [GO:0010468] GO:0004540; GO:0005737; GO:0005777; GO:0005794; GO:0006302; GO:0007143; GO:0010468; GO:0016020; GO:0043231; GO:0048477; GO:1903231; GO:1905762 27982 XM_029333515.2 117 42 30 106 104 B8VIU6 1.8e-59 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 27983 XM_029346335.2 13 12 18 1 1 NA NA NA NA NA NA 27984 XR_003823477.2 4 3 20 0 73 NA NA NA NA NA NA 27985 XR_003826809.2 101 115 126 164 244 NA NA NA NA NA NA 27986 XM_044325529.1 19 52 175 36 58 B1AS29 1.72e-82 Glutamate receptor ionotropic, kainate 3 (GluK3) (Glutamate receptor 7) (GluR-7) (GluR7) Mus musculus (Mouse) G protein-coupled glutamate receptor signaling pathway [GO:0007216]; glutamate receptor signaling pathway [GO:0007215]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; regulation of membrane potential [GO:0042391]; synaptic transmission, glutamatergic [GO:0035249] GO:0001640; GO:0004970; GO:0005886; GO:0007215; GO:0007216; GO:0008066; GO:0015276; GO:0015277; GO:0030424; GO:0030425; GO:0032839; GO:0032983; GO:0035249; GO:0038023; GO:0042391; GO:0042734; GO:0043195; GO:0043204; GO:0045211; GO:0050804; GO:0051967; GO:0098978; GO:0099507; GO:1904315 27987 XM_044324804.1 252 99 106 241 226 Q9Y2G3 0 Phospholipid-transporting ATPase IF (EC 7.6.2.1) (ATPase IR) (ATPase class VI type 11B) (P4-ATPase flippase complex alpha subunit ATP11B) Homo sapiens (Human) aminophospholipid transport [GO:0015917]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; phospholipid translocation [GO:0045332] GO:0000287; GO:0005524; GO:0005637; GO:0005783; GO:0005802; GO:0005886; GO:0006811; GO:0015075; GO:0015917; GO:0016020; GO:0016887; GO:0031901; GO:0034220; GO:0035577; GO:0045332; GO:0055037; GO:0055038; GO:0090555; GO:0090556; GO:0140326; GO:1990531 27988 XM_029351392.2 2409 1696 1250 2097 1473 NA NA NA NA NA NA 27989 XM_044319386.1 16 51 3 32 1 Q9UHC6 6.15e-37 Contactin-associated protein-like 2 (Cell recognition molecule Caspr2) Homo sapiens (Human) adult behavior [GO:0030534]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell population proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; clustering of voltage-gated potassium channels [GO:0045163]; learning [GO:0007612]; limbic system development [GO:0021761]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuron recognition [GO:0008038]; positive regulation of gap junction assembly [GO:1903598]; protein localization to juxtaparanode region of axon [GO:0071205]; social behavior [GO:0035176]; striatum development [GO:0021756]; superior temporal gyrus development [GO:0071109]; thalamus development [GO:0021794]; transmission of nerve impulse [GO:0019226]; vocal learning [GO:0042297]; vocalization behavior [GO:0071625] GO:0005769; GO:0005794; GO:0007155; GO:0007420; GO:0007612; GO:0008038; GO:0008076; GO:0008283; GO:0009986; GO:0016020; GO:0019226; GO:0019899; GO:0021756; GO:0021761; GO:0021794; GO:0021987; GO:0030424; GO:0030425; GO:0030534; GO:0030673; GO:0031175; GO:0033010; GO:0035176; GO:0042297; GO:0043025; GO:0043204; GO:0044224; GO:0045163; GO:0048812; GO:0071109; GO:0071205; GO:0071625; GO:1903598 27990 XM_044315188.1 205 50 50 63 74 NA NA NA NA NA NA 27991 XM_029329902.2 0 0 0 59 39 P47972 1.27e-23 Neuronal pentraxin-2 (NP2) (Neuronal pentraxin II) (NP-II) Homo sapiens (Human) associative learning [GO:0008306]; chemical synaptic transmission [GO:0007268]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962] GO:0005576; GO:0007268; GO:0008306; GO:0030246; GO:0046872; GO:0098962; GO:0098978 27992 XM_029325336.2 456 325 156 586 29 NA NA NA NA NA NA 27993 XM_029330564.2 0 0 0 0 11 Q9Y5X5 1.26e-30 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (G-protein coupled receptor HLWAR77) (Neuropeptide G-protein coupled receptor) Homo sapiens (Human) detection of abiotic stimulus [GO:0009582]; G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0009582; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 27994 XM_044324411.1 0 0 0 96 0 NA NA NA NA NA NA 27995 XM_029340667.2 125 203 22 325 335 Q6P0C6 3.82e-48 LHFPL tetraspan subfamily member 2a protein Danio rerio (Zebrafish) (Brachydanio rerio) development of primary female sexual characteristics [GO:0046545]; development of primary male sexual characteristics [GO:0046546]; positive regulation of fertilization [GO:1905516]; single fertilization [GO:0007338] GO:0007338; GO:0016020; GO:0046545; GO:0046546; GO:1905516 27996 XM_029330061.2 58 57 125 156 95 A1L1W9 3.01e-44 Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10) Danio rerio (Zebrafish) (Brachydanio rerio) aromatic amino acid transport [GO:0015801]; thyroid hormone transport [GO:0070327] GO:0005302; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0070327 27997 XM_044324007.1 0 0 32 0 5 NA NA NA NA NA NA 27998 XM_044311374.1 134 8 2 4 8 NA NA NA NA NA NA 27999 XM_044314581.1 11 0 8 56 42 NA NA NA NA NA NA 28000 XM_029346083.2 163 153 201 186 605 Q9WTN5 1.19e-56 Two pore calcium channel protein 1 (Voltage-dependent calcium channel protein TPC1) Rattus norvegicus (Rat) endocytosis involved in viral entry into host cell [GO:0075509]; positive regulation of autophagy [GO:0010508]; regulation of ion transmembrane transport [GO:0034765]; sodium ion transmembrane transport [GO:0035725] GO:0005244; GO:0005248; GO:0005765; GO:0010008; GO:0010508; GO:0015280; GO:0016020; GO:0019905; GO:0031901; GO:0034765; GO:0035725; GO:0036019; GO:0042802; GO:0042803; GO:0055038; GO:0072345; GO:0075509; GO:0080025; GO:0097682 28001 XM_029331058.2 46247 32337 23256 44799 33603 Q2EJA0 1.24e-45 Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog) Rattus norvegicus (Rat) blastocyst development [GO:0001824]; bud elongation involved in lung branching [GO:0060449]; canonical Wnt signaling pathway [GO:0060070]; cardiac muscle tissue regeneration [GO:0061026]; cell morphogenesis [GO:0000902]; cell population proliferation [GO:0008283]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; cellular response to retinoic acid [GO:0071300]; contact inhibition [GO:0060242]; embryonic heart tube morphogenesis [GO:0003143]; enterocyte differentiation [GO:1903703]; epithelial cell proliferation [GO:0050673]; extrinsic apoptotic signaling pathway [GO:0097191]; glandular epithelial cell differentiation [GO:0002067]; heart process [GO:0003015]; hippo signaling [GO:0035329]; interleukin-6-mediated signaling pathway [GO:0070102]; intestinal epithelial cell development [GO:0060576]; intestinal epithelial cell differentiation [GO:0060575]; keratinocyte differentiation [GO:0030216]; lateral mesoderm development [GO:0048368]; lung epithelial cell differentiation [GO:0060487]; negative regulation of cilium assembly [GO:1902018]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of epithelial cell differentiation [GO:0030857]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of stem cell differentiation [GO:2000737]; negative regulation of transcription by RNA polymerase II [GO:0000122]; notochord development [GO:0030903]; organ growth [GO:0035265]; paraxial mesoderm development [GO:0048339]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of gene expression [GO:0010628]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of organ growth [GO:0046622]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; progesterone receptor signaling pathway [GO:0050847]; protein-containing complex assembly [GO:0065003]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of cell population proliferation [GO:0042127]; regulation of gene expression [GO:0010468]; regulation of keratinocyte proliferation [GO:0010837]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]; regulation of neurogenesis [GO:0050767]; regulation of stem cell proliferation [GO:0072091]; response to progesterone [GO:0032570]; signal transduction in response to DNA damage [GO:0042770]; somatic stem cell population maintenance [GO:0035019]; stem cell proliferation [GO:0072089]; tissue homeostasis [GO:0001894]; trophectodermal cell differentiation [GO:0001829]; vasculogenesis [GO:0001570]; wound healing [GO:0042060] GO:0000122; GO:0000902; GO:0000976; GO:0000978; GO:0001570; GO:0001674; GO:0001824; GO:0001829; GO:0001894; GO:0002067; GO:0003015; GO:0003143; GO:0003682; GO:0003713; GO:0003714; GO:0005634; GO:0005654; GO:0005667; GO:0005737; GO:0005829; GO:0006974; GO:0008022; GO:0008283; GO:0008284; GO:0010468; GO:0010628; GO:0010629; GO:0010837; GO:0016020; GO:0030054; GO:0030216; GO:0030307; GO:0030857; GO:0030903; GO:0032570; GO:0033148; GO:0035019; GO:0035265; GO:0035329; GO:0042060; GO:0042127; GO:0042770; GO:0045599; GO:0045669; GO:0045747; GO:0045893; GO:0045944; GO:0046622; GO:0048339; GO:0048368; GO:0050673; GO:0050679; GO:0050767; GO:0050847; GO:0060045; GO:0060070; GO:0060242; GO:0060449; GO:0060487; GO:0060575; GO:0060576; GO:0060828; GO:0061026; GO:0065003; GO:0070064; GO:0070102; GO:0071300; GO:0071480; GO:0072089; GO:0072091; GO:0072307; GO:0090263; GO:0097191; GO:0140297; GO:0140552; GO:0140678; GO:1900182; GO:1902018; GO:1902459; GO:1903703; GO:1904036; GO:2000648; GO:2000737; GO:2001237 28002 XM_029343349.2 902 628 496 822 791 O46382 0 Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (ADP-ribosylation factor guanine nucleotide-exchange factor 1) (p200 ARF guanine nucleotide exchange factor) (p200 ARF-GEP1) Bos taurus (Bovine) endomembrane system organization [GO:0010256]; Golgi organization [GO:0007030]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of GTPase activity [GO:0034260]; positive regulation of wound healing [GO:0090303]; protein glycosylation [GO:0006486]; protein transport [GO:0015031]; regulation of ARF protein signal transduction [GO:0032012]; regulation of establishment of cell polarity [GO:2000114] GO:0000139; GO:0005085; GO:0005730; GO:0005802; GO:0005829; GO:0006486; GO:0007030; GO:0010256; GO:0015031; GO:0016363; GO:0030532; GO:0030837; GO:0032012; GO:0034237; GO:0034260; GO:0048471; GO:0090303; GO:2000114 28003 XM_029343349.2 902 628 496 822 791 O46382 1.94e-85 Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (ADP-ribosylation factor guanine nucleotide-exchange factor 1) (p200 ARF guanine nucleotide exchange factor) (p200 ARF-GEP1) Bos taurus (Bovine) endomembrane system organization [GO:0010256]; Golgi organization [GO:0007030]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of GTPase activity [GO:0034260]; positive regulation of wound healing [GO:0090303]; protein glycosylation [GO:0006486]; protein transport [GO:0015031]; regulation of ARF protein signal transduction [GO:0032012]; regulation of establishment of cell polarity [GO:2000114] GO:0000139; GO:0005085; GO:0005730; GO:0005802; GO:0005829; GO:0006486; GO:0007030; GO:0010256; GO:0015031; GO:0016363; GO:0030532; GO:0030837; GO:0032012; GO:0034237; GO:0034260; GO:0048471; GO:0090303; GO:2000114 28004 XM_044325241.1 1062 625 1164 468 784 Q61093 2.46e-178 Cytochrome b-245 heavy chain (EC 1.-.-.-) (CGD91-phox) (Cytochrome b(558) subunit beta) (Cytochrome b558 subunit beta) (Heme-binding membrane glycoprotein gp91phox) (Neutrophil cytochrome b 91 kDa polypeptide) (gp91-1) (gp91-phox) (p22 phagocyte B-cytochrome) Mus musculus (Mouse) cellular response to cadmium ion [GO:0071276]; cellular response to ethanol [GO:0071361]; cellular response to L-glutamine [GO:1904845]; defense response [GO:0006952]; hydrogen peroxide biosynthetic process [GO:0050665]; hypoxia-inducible factor-1alpha signaling pathway [GO:0097411]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; positive regulation of angiogenesis [GO:0045766]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of ion transmembrane transport [GO:0034765]; respiratory burst [GO:0045730]; response to aldosterone [GO:1904044]; response to angiotensin [GO:1990776]; response to nutrient [GO:0007584]; response to xenobiotic stimulus [GO:0009410]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801] GO:0005244; GO:0005635; GO:0005737; GO:0005739; GO:0005783; GO:0005791; GO:0005794; GO:0005886; GO:0006801; GO:0006952; GO:0006954; GO:0007584; GO:0009055; GO:0009410; GO:0016175; GO:0020037; GO:0030425; GO:0032760; GO:0034765; GO:0042554; GO:0043020; GO:0043025; GO:0045087; GO:0045335; GO:0045730; GO:0045766; GO:0046872; GO:0046982; GO:0050660; GO:0050665; GO:0071276; GO:0071361; GO:0097038; GO:0097411; GO:1904044; GO:1904845; GO:1990776 28005 XM_029329901.2 150 124 0 0 0 O31463 4.78e-44 Homocysteine S-methyltransferase YbgG (EC 2.1.1.10) (S-methylmethionine:homocysteine methyltransferase) Bacillus subtilis (strain 168) methionine biosynthetic process [GO:0009086]; methylation [GO:0032259]; S-methylmethionine cycle [GO:0033528] GO:0008270; GO:0008898; GO:0009086; GO:0032259; GO:0033528; GO:0061627 28006 XM_044323852.1 13 6 12 6 114 NA NA NA NA NA NA 28007 XM_029339277.2 2 2 0 4 12 Q8C1R0 6.1e-85 Testis-specific serine/threonine-protein kinase 5 (TSK-5) (TSSK-5) (Testis-specific kinase 5) (EC 2.7.11.1) Mus musculus (Mouse) cell differentiation [GO:0030154]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]; spermatogenesis [GO:0007283] GO:0000287; GO:0004674; GO:0005524; GO:0006468; GO:0007283; GO:0030154; GO:0035556; GO:0106310 28008 XM_029329634.2 392 296 240 254 408 Q5RB81 1.14e-83 Histone-lysine N-methyltransferase SUV39H1 (EC 2.1.1.355) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cell cycle [GO:0007049]; cell differentiation [GO:0030154]; chromatin organization [GO:0006325]; histone lysine methylation [GO:0034968]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of DNA-templated transcription [GO:0045892]; rhythmic process [GO:0048511]; rRNA processing [GO:0006364] GO:0000775; GO:0000792; GO:0000976; GO:0005634; GO:0005652; GO:0005654; GO:0006325; GO:0006364; GO:0007049; GO:0008270; GO:0030154; GO:0034968; GO:0042754; GO:0045892; GO:0046974; GO:0048511; GO:0140949 28009 XM_044318392.1 152 63 35 121 111 NA NA NA NA NA NA 28010 XM_044310309.1 110 4 243 0 712 Q9NR20 2.72e-81 Dual specificity tyrosine-phosphorylation-regulated kinase 4 (EC 2.7.12.1) Homo sapiens (Human) peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107] GO:0004674; GO:0004712; GO:0004713; GO:0005524; GO:0005634; GO:0005737; GO:0005856; GO:0018105; GO:0018107; GO:0043231; GO:0046872; GO:0106310 28011 XM_044324618.1 430 325 436 440 163 Q9DC37 4.67e-180 Major facilitator superfamily domain-containing protein 1 Mus musculus (Mouse) protein localization to lysosome [GO:0061462]; protein stabilization [GO:0050821] GO:0005764; GO:0005765; GO:0022857; GO:0042803; GO:0050821; GO:0061462 28012 XM_044307045.1 74 0 0 1277 8 O75445 5.83e-115 Usherin (Usher syndrome type IIa protein) (Usher syndrome type-2A protein) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear receptor cell differentiation [GO:0060113]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0001917; GO:0002141; GO:0002142; GO:0005518; GO:0005576; GO:0005604; GO:0005737; GO:0007601; GO:0007605; GO:0009887; GO:0009888; GO:0016324; GO:0016477; GO:0017022; GO:0032391; GO:0032421; GO:0034446; GO:0035315; GO:0036064; GO:0042491; GO:0042802; GO:0045184; GO:0045494; GO:0048496; GO:0050896; GO:0050953; GO:0051649; GO:0060113; GO:0060171; GO:1990075; GO:1990696 28013 XR_003828583.2 78 52 85 123 210 NA NA NA NA NA NA 28014 XM_029340964.2 760 224 144 422 456 H3BPM6 4.02e-32 MKRN2 opposite strand protein (MKRN2 antisense RNA 1) (MKRN2 antisense gene protein 1) Homo sapiens (Human) NA NA 28015 XM_029325997.2 1146 828 524 936 1104 Q91WD1 3.5e-38 DNA-directed RNA polymerase III subunit RPC4 (RNA polymerase III subunit C4) (DNA-directed RNA polymerase III subunit D) Mus musculus (Mouse) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-beta production [GO:0032728]; transcription by RNA polymerase III [GO:0006383] GO:0003677; GO:0003682; GO:0005634; GO:0005654; GO:0005666; GO:0005829; GO:0006383; GO:0032728; GO:0045087; GO:0045089; GO:0051607 28016 XM_029346403.2 5 6 0 2 0 NA NA NA NA NA NA 28017 XM_029333185.2 30 2 13 28 31 Q94K49 6.68e-40 Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1 (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) epigenetic regulation of gene expression [GO:0040029] GO:0003682; GO:0004518; GO:0005634; GO:0035098; GO:0035102; GO:0040029; GO:0046872 28018 XM_029343327.2 1052 768 568 859 942 Q5RBH9 5.41e-167 Nuclear receptor-binding protein Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; protein phosphorylation [GO:0006468] GO:0005938; GO:0006468; GO:0006888; GO:0012505; GO:0016020; GO:0030027; GO:0048471 28019 XM_044314748.1 0 0 1 0 7 NA NA NA NA NA NA 28020 XM_029356921.2 5 13 4 1 11 NA NA NA NA NA NA 28021 XM_044327191.1 0 21 0 0 3 NA NA NA NA NA NA 28022 XM_044317949.1 0 0 0 125 0 Q8NI36 0 WD repeat-containing protein 36 (T-cell activation WD repeat-containing protein) (TA-WDRP) Homo sapiens (Human) response to stimulus [GO:0050896]; rRNA processing [GO:0006364]; visual perception [GO:0007601] GO:0003723; GO:0005654; GO:0005730; GO:0006364; GO:0007601; GO:0032040; GO:0034388; GO:0050896 28023 XM_044319654.1 4480 3827 5537 3136 1841 Q25532 3.85e-30 V-type proton ATPase subunit G (V-ATPase subunit G) (V-ATPase 13 kDa subunit) (Vacuolar proton pump subunit G) Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm) NA GO:0016324; GO:0016471; GO:0046961 28024 XR_003825904.2 59 59 42 47 90 P97292 2.21e-29 Histamine H2 receptor (H2R) (HH2R) (Gastric receptor I) Mus musculus (Mouse) chemical synaptic transmission [GO:0007268]; digestive tract development [GO:0048565]; epithelial cell morphogenesis [GO:0003382]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; gastric acid secretion [GO:0001696]; gastrin-induced gastric acid secretion [GO:0001698]; gland development [GO:0048732]; histamine-induced gastric acid secretion [GO:0001697]; memory [GO:0007613]; negative regulation of arachidonic acid secretion [GO:1900139]; positive regulation of vasoconstriction [GO:0045907]; regulation of synaptic plasticity [GO:0048167]; toxin transport [GO:1901998]; visual learning [GO:0008542] GO:0001696; GO:0001697; GO:0001698; GO:0003382; GO:0004969; GO:0004993; GO:0005886; GO:0007187; GO:0007268; GO:0007613; GO:0008542; GO:0016020; GO:0030425; GO:0030594; GO:0045202; GO:0045907; GO:0048167; GO:0048565; GO:0048732; GO:1900139; GO:1901363; GO:1901998 28025 XM_044319257.1 676 252 119 363 369 Q8BHB0 3.9e-43 Nucleotide-binding oligomerization domain-containing protein 1 (Caspase recruitment domain-containing protein 4) Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cellular response to muramyl dipeptide [GO:0071225]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; ERK1 and ERK2 cascade [GO:0070371]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of cell death [GO:0010942]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of xenophagy [GO:1904417]; regulation of apoptotic process [GO:0042981]; stress-activated MAPK cascade [GO:0051403]; xenophagy [GO:0098792] GO:0002221; GO:0002606; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006915; GO:0006919; GO:0007249; GO:0007254; GO:0010942; GO:0016045; GO:0016323; GO:0016324; GO:0032731; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0035556; GO:0038187; GO:0042742; GO:0042802; GO:0042803; GO:0042981; GO:0043123; GO:0043280; GO:0044877; GO:0045087; GO:0045335; GO:0046330; GO:0050700; GO:0050830; GO:0051000; GO:0051092; GO:0051403; GO:0060907; GO:0070371; GO:0070374; GO:0071225; GO:0098792; GO:1901224; GO:1904417 28026 XM_029328855.2 555 429 522 489 624 NA NA NA NA NA NA 28027 XR_006398034.1 90 72 47 25 116 Q5RCY5 4.69e-57 Protein asteroid homolog 1 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0004518 28028 XR_006398034.1 90 72 47 25 116 Q5RCY5 4.69e-57 Protein asteroid homolog 1 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0004518 28029 XM_044324479.1 10 52 55 9 26 Q96AY4 7.52e-101 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28030 XM_044324479.1 10 52 55 9 26 Q96AY4 6.03e-78 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28031 XM_044324479.1 10 52 55 9 26 Q96AY4 1.53e-72 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28032 XM_044324479.1 10 52 55 9 26 Q96AY4 3.18e-69 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28033 XM_044324479.1 10 52 55 9 26 Q96AY4 1.32e-67 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28034 XM_044324479.1 10 52 55 9 26 Q96AY4 6.41e-64 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28035 XR_006396692.1 32 3 12 479 16 NA NA NA NA NA NA 28036 XM_029352045.2 438 695 837 388 311 NA NA NA NA NA NA 28037 XM_044306860.1 762 755 495 945 406 B3EWY9 0 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 28038 XM_044306860.1 762 755 495 945 406 B3EWY9 1.12e-101 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 28039 XM_044308025.1 383 313 324 313 320 Q3SZZ0 2.24e-113 Ribosome biogenesis protein BRX1 homolog (Brix domain-containing protein 2) Bos taurus (Bovine) ribosomal large subunit assembly [GO:0000027]; rRNA processing [GO:0006364] GO:0000027; GO:0003723; GO:0005694; GO:0005730; GO:0006364; GO:0019843 28040 XM_044314059.1 3 0 0 3 15 NA NA NA NA NA NA 28041 XM_029351876.2 554 384 367 540 928 Q9H2F5 5.78e-119 Enhancer of polycomb homolog 1 Homo sapiens (Human) DNA-templated transcription [GO:0006351]; double-strand break repair via homologous recombination [GO:0000724]; histone acetylation [GO:0016573]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of double-strand break repair [GO:2000779]; regulation of transcription by RNA polymerase II [GO:0006357]; sperm DNA condensation [GO:0035092]; spermatid development [GO:0007286] GO:0000122; GO:0000724; GO:0000786; GO:0005634; GO:0005654; GO:0005737; GO:0006351; GO:0006357; GO:0007286; GO:0016573; GO:0031965; GO:0032777; GO:0035092; GO:0035267; GO:0042981; GO:0043231; GO:0043967; GO:0043968; GO:0045814; GO:0045892; GO:0045893; GO:0045944; GO:0051726; GO:0140463; GO:0140767; GO:1905168; GO:2000779 28042 XM_044319587.1 25 5 16 38 87 NA NA NA NA NA NA 28043 XM_044325328.1 17 22 11 4 29 A6QLU6 1.13e-68 Adhesion G-protein coupled receptor D1 (G-protein coupled receptor 133) Bos taurus (Bovine) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0005886; GO:0007166; GO:0007186; GO:0007189 28044 XM_044313225.1 46 13 49 20 57 Q8TE57 1.16e-108 A disintegrin and metalloproteinase with thrombospondin motifs 16 (ADAM-TS 16) (ADAM-TS16) (ADAMTS-16) (EC 3.4.24.-) Homo sapiens (Human) branching involved in ureteric bud morphogenesis [GO:0001658]; extracellular matrix organization [GO:0030198]; male gamete generation [GO:0048232]; proteolysis [GO:0006508]; regulation of cilium assembly [GO:1902017]; regulation of systemic arterial blood pressure [GO:0003073] GO:0001658; GO:0003073; GO:0004222; GO:0005576; GO:0006508; GO:0030198; GO:0031012; GO:0046872; GO:0048232; GO:1902017 28045 XM_029337489.2 33 38 0 21 0 O09118 0 Netrin-1 Mus musculus (Mouse) animal organ morphogenesis [GO:0009887]; anterior/posterior axon guidance [GO:0033564]; apoptotic process [GO:0006915]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; B cell mediated immunity [GO:0019724]; B cell proliferation [GO:0042100]; Cdc42 protein signal transduction [GO:0032488]; cell population proliferation [GO:0008283]; cell-cell adhesion [GO:0098609]; chemorepulsion of axon [GO:0061643]; dendrite development [GO:0016358]; glial cell proliferation [GO:0014009]; inner ear morphogenesis [GO:0042472]; mammary gland development [GO:0030879]; mammary gland duct morphogenesis [GO:0060603]; motor neuron axon guidance [GO:0008045]; motor neuron migration [GO:0097475]; negative regulation of axon extension [GO:0030517]; neuron migration [GO:0001764]; nuclear migration [GO:0007097]; positive regulation of axon extension [GO:0045773]; positive regulation of cell motility [GO:2000147]; positive regulation of glial cell proliferation [GO:0060252]; Ras protein signal transduction [GO:0007265]; regulation of cell migration [GO:0030334]; regulation of glial cell migration [GO:1903975]; regulation of synapse assembly [GO:0051963]; substrate-dependent cell migration, cell extension [GO:0006930]; T cell mediated immunity [GO:0002456]; tissue development [GO:0009888] GO:0001764; GO:0002456; GO:0005125; GO:0005576; GO:0005604; GO:0005654; GO:0005737; GO:0005829; GO:0006915; GO:0006930; GO:0007097; GO:0007265; GO:0007409; GO:0007411; GO:0008045; GO:0008283; GO:0009887; GO:0009888; GO:0014009; GO:0015629; GO:0016358; GO:0019724; GO:0030334; GO:0030517; GO:0030879; GO:0031012; GO:0032488; GO:0033564; GO:0042100; GO:0042472; GO:0045773; GO:0051963; GO:0060252; GO:0060603; GO:0061643; GO:0062023; GO:0071944; GO:0097475; GO:0098609; GO:1903975; GO:2000147 28046 XM_029334059.2 1735 2926 2205 1997 2165 NA NA NA NA NA NA 28047 XM_029350200.2 49 25 62 45 1 NA NA NA NA NA NA 28048 XM_029345777.2 12712 18314 8271 12186 8448 Q02543 4.5e-90 60S ribosomal protein L18a (Large ribosomal subunit protein eL20) Homo sapiens (Human) cytoplasmic translation [GO:0002181]; translation [GO:0006412] GO:0002181; GO:0003723; GO:0003735; GO:0005737; GO:0005829; GO:0006412; GO:0016020; GO:0022625; GO:0022626; GO:0042788 28049 XM_044329321.1 176 117 117 342 315 Q9Y394 5.79e-75 Dehydrogenase/reductase SDR family member 7 (EC 1.1.1.-) (Retinal short-chain dehydrogenase/reductase 4) (retSDR4) (Short chain dehydrogenase/reductase family 34C member 1) (Protein SDR34C1) Homo sapiens (Human) NA GO:0004090; GO:0005789; GO:0016020; GO:0016616; GO:0052650 28050 XM_044322841.1 19 16 16 25 25 NA NA NA NA NA NA 28051 XR_006395496.1 2 16 2 26 17 NA NA NA NA NA NA 28052 XM_029338686.2 705 865 580 653 1110 NA NA NA NA NA NA 28053 XM_029357443.2 0 54 51 231 199 O43196 0 MutS protein homolog 5 (hMSH5) Homo sapiens (Human) chiasma assembly [GO:0051026]; mismatch repair [GO:0006298] GO:0003690; GO:0005524; GO:0005634; GO:0006298; GO:0030983; GO:0051026; GO:0140664 28054 XM_044319649.1 26 13 33 10 35 NA NA NA NA NA NA 28055 XM_044319663.1 297 189 64 165 172 Q9CYL5 2.1e-24 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Mus musculus (Mouse) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070374 28056 XM_044314484.1 3181 824 947 1952 1986 NA NA NA NA NA NA 28057 XM_029343550.2 287 191 196 258 228 Q8C8M1 4.13e-35 SIN3-HDAC complex-associated factor (Protein FAM60A) (Tera protein) Mus musculus (Mouse) negative regulation of cell differentiation [GO:0045596]; negative regulation of cell migration [GO:0030336]; negative regulation of stem cell population maintenance [GO:1902455]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of stem cell population maintenance [GO:1902459] GO:0000122; GO:0005634; GO:0008284; GO:0016580; GO:0030336; GO:0030512; GO:0045596; GO:1902455; GO:1902459 28058 XM_029351881.2 105 34 87 20 187 O15973 3.34e-26 Rhodopsin, GQ-coupled (GQ-rhodopsin) Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis) phototransduction [GO:0007602]; visual perception [GO:0007601] GO:0004930; GO:0005886; GO:0007601; GO:0007602; GO:0009881 28059 XM_029327142.2 165 226 174 61 290 Q9NRW4 2.96e-63 Dual specificity protein phosphatase 22 (EC 3.1.3.16) (EC 3.1.3.48) (JNK-stimulatory phosphatase-1) (JSP-1) (Low molecular weight dual specificity phosphatase 2) (LMW-DSP2) (Mitogen-activated protein kinase phosphatase x) (MAP kinase phosphatase x) (MKP-x) Homo sapiens (Human) cellular response to epidermal growth factor stimulus [GO:0071364]; dephosphorylation [GO:0016311]; negative regulation of cell migration [GO:0030336]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903996]; negative regulation of T cell activation [GO:0050868]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-tyrosine dephosphorylation [GO:0035335]; positive regulation of JNK cascade [GO:0046330]; regulation of cell population proliferation [GO:0042127]; signal transduction [GO:0007165]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0000122; GO:0002710; GO:0004725; GO:0004726; GO:0005737; GO:0005829; GO:0005886; GO:0007165; GO:0007179; GO:0008138; GO:0016311; GO:0017018; GO:0030336; GO:0031941; GO:0035335; GO:0042127; GO:0046330; GO:0050860; GO:0050868; GO:0051895; GO:0061851; GO:0071364; GO:1903996; GO:1990782 28060 XM_029328540.2 52 33 26 37 151 NA NA NA NA NA NA 28061 XM_044329333.1 123 201 39 0 168 NA NA NA NA NA NA 28062 XM_044328455.1 660 670 306 445 409 Q4R7R1 3.53e-146 Short-chain dehydrogenase/reductase family 42E member 1 (EC 1.1.1.-) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) steroid biosynthetic process [GO:0006694] GO:0003854; GO:0006694; GO:0016020 28063 XM_044322454.1 41 30 91 32 63 NA NA NA NA NA NA 28064 XR_006392233.1 27 25 128 3 20 NA NA NA NA NA NA 28065 XM_029350892.2 1250 3162 1502 2540 2916 NA NA NA NA NA NA 28066 XM_044328081.1 68 0 25 23 65 NA NA NA NA NA NA 28067 XM_044312018.1 1 0 9 4 15 NA NA NA NA NA NA 28068 XM_029351086.2 0 0 3 6 11 NA NA NA NA NA NA 28069 XR_006392733.1 0 94 89 62 68 NA NA NA NA NA NA 28070 XM_029329080.2 1962 2033 1609 1687 865 Q9UBF6 2.86e-51 RING-box protein 2 (Rbx2) (CKII beta-binding protein 1) (CKBBP1) (RING finger protein 7) (Regulator of cullins 2) (Sensitive to apoptosis gene protein) Homo sapiens (Human) post-translational protein modification [GO:0043687]; protein neddylation [GO:0045116]; protein ubiquitination [GO:0016567]; response to redox state [GO:0051775]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0005507; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006511; GO:0008270; GO:0016567; GO:0019788; GO:0031461; GO:0031466; GO:0043687; GO:0045116; GO:0051775; GO:0061630; GO:0061663; GO:0097602 28071 XM_029323728.2 780 398 431 816 777 Q7Z4L5 0 Tetratricopeptide repeat protein 21B (TPR repeat protein 21B) (Intraflagellar transport 139 homolog) Homo sapiens (Human) Bergmann glial cell differentiation [GO:0060020]; cerebellar Purkinje cell differentiation [GO:0021702]; cilium assembly [GO:0060271]; forebrain dorsal/ventral pattern formation [GO:0021798]; intraciliary retrograde transport [GO:0035721]; negative regulation of eating behavior [GO:1903999]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; protein localization to cilium [GO:0061512]; protein localization to non-motile cilium [GO:0097499]; regulation of intraciliary retrograde transport [GO:1905799]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription by RNA polymerase II [GO:0006357]; smoothened signaling pathway [GO:0007224]; ventricular system development [GO:0021591] GO:0003682; GO:0005737; GO:0005856; GO:0005929; GO:0006357; GO:0007224; GO:0008589; GO:0010628; GO:0021591; GO:0021702; GO:0021798; GO:0030991; GO:0035721; GO:0060020; GO:0060271; GO:0061512; GO:0090263; GO:0097499; GO:0097542; GO:1903999; GO:1905799 28072 XM_044323165.1 384 136 188 236 404 Q9CR50 4.57e-26 RING finger and CHY zinc finger domain-containing protein 1 (EC 2.3.2.27) (Androgen receptor N-terminal-interacting protein) (CH-rich-interacting match with PLAG1) (E3 ubiquitin-protein ligase Pirh2) (RING-type E3 ubiquitin transferase RCHY1) (Zinc finger protein 363) Mus musculus (Mouse) positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; protein autoubiquitination [GO:0051865]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000151; GO:0002039; GO:0005102; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006511; GO:0008270; GO:0016567; GO:0016607; GO:0031398; GO:0032436; GO:0042803; GO:0043231; GO:0051865; GO:0061630 28073 XM_029352744.2 850 768 537 325 627 NA NA NA NA NA NA 28074 XM_029345608.2 1390 946 592 1055 1375 P42207 2.62e-158 Septin-1 (DIFF6 protein homolog) (Protein innocent bystander) Drosophila melanogaster (Fruit fly) cellularization [GO:0007349]; cytoskeleton-dependent cytokinesis [GO:0061640]; imaginal disc-derived wing morphogenesis [GO:0007476]; positive regulation of apoptotic process [GO:0043065]; regulation of exocytosis [GO:0017157] GO:0003924; GO:0005525; GO:0005940; GO:0007349; GO:0007476; GO:0008021; GO:0015630; GO:0017157; GO:0031105; GO:0031625; GO:0032153; GO:0032154; GO:0042803; GO:0043065; GO:0060090; GO:0061640 28075 XM_044325286.1 19 0 11 0 38 NA NA NA NA NA NA 28076 XM_044317957.1 10 20 83 16 76 NA NA NA NA NA NA 28077 XM_044317990.1 717 588 383 655 870 Q5ZI89 0 Trafficking protein particle complex subunit 11 Gallus gallus (Chicken) vesicle-mediated transport [GO:0016192] GO:0005794; GO:0016192 28078 XM_029350571.2 3893 3437 2741 4722 5491 Q14677 7.24e-77 Clathrin interactor 1 (Clathrin-interacting protein localized in the trans-Golgi region) (Clint) (Enthoprotin) (Epsin-4) (Epsin-related protein) (EpsinR) Homo sapiens (Human) endocytosis [GO:0006897] GO:0005543; GO:0005654; GO:0005768; GO:0005794; GO:0005829; GO:0005886; GO:0006897; GO:0016020; GO:0030125; GO:0030276; GO:0043231; GO:0045296; GO:0048471 28079 XM_029358364.2 1669 676 1063 1502 1433 Q62824 0 Exocyst complex component 4 (Exocyst complex component Sec8) (rSec8) Rattus norvegicus (Rat) chemical synaptic transmission [GO:0007268]; establishment of cell polarity [GO:0030010]; exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; Golgi to transport vesicle transport [GO:0055108]; membrane biogenesis [GO:0044091]; oligodendrocyte differentiation [GO:0048709]; paraxial mesoderm formation [GO:0048341]; positive regulation of calcium-mediated signaling [GO:0050850]; protein targeting to membrane [GO:0006612]; regulation of protein transport [GO:0051223]; vesicle docking involved in exocytosis [GO:0006904]; vesicle targeting [GO:0006903]; vesicle tethering involved in exocytosis [GO:0090522] GO:0000145; GO:0005813; GO:0005902; GO:0006612; GO:0006887; GO:0006893; GO:0006903; GO:0006904; GO:0007268; GO:0008021; GO:0014069; GO:0016020; GO:0030010; GO:0030165; GO:0030425; GO:0030426; GO:0031252; GO:0031267; GO:0032584; GO:0032991; GO:0035255; GO:0035748; GO:0043005; GO:0043025; GO:0043198; GO:0043209; GO:0044091; GO:0044877; GO:0045202; GO:0047485; GO:0048341; GO:0048709; GO:0050850; GO:0051223; GO:0055108; GO:0090522; GO:0090543; GO:0098685; GO:0099092 28080 XM_044311887.1 311 114 113 184 330 NA NA NA NA NA NA 28081 XM_044313773.1 11 104 0 0 101 NA NA NA NA NA NA 28082 XM_044319012.1 647 606 382 647 615 F1QC45 2.77e-110 Protein XRP2 Danio rerio (Zebrafish) (Brachydanio rerio) determination of heart left/right asymmetry [GO:0061371]; heart looping [GO:0001947]; photoreceptor cell development [GO:0042461]; photoreceptor cell maintenance [GO:0045494]; photoreceptor cell outer segment organization [GO:0035845]; post-Golgi vesicle-mediated transport [GO:0006892]; pronephros development [GO:0048793]; protein transport [GO:0015031]; retina development in camera-type eye [GO:0060041]; retina layer formation [GO:0010842] GO:0001947; GO:0005096; GO:0005525; GO:0005929; GO:0006892; GO:0010842; GO:0015031; GO:0035845; GO:0042461; GO:0045494; GO:0048793; GO:0060041; GO:0061371; GO:1990075 28083 XM_044315067.1 5 9 10 4 0 NA NA NA NA NA NA 28084 XM_029329954.2 69 168 117 89 77 Q16445 1.34e-55 Gamma-aminobutyric acid receptor subunit alpha-6 (GABA(A) receptor subunit alpha-6) Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid signaling pathway [GO:0007214]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; regulation of postsynaptic membrane potential [GO:0060078]; signal transduction [GO:0007165]; synaptic transmission, GABAergic [GO:0051932] GO:0004890; GO:0005231; GO:0005237; GO:0005886; GO:0007165; GO:0007214; GO:0007268; GO:0008503; GO:0022851; GO:0030594; GO:0032590; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051932; GO:0060078; GO:0098794; GO:0099192; GO:1902476; GO:1902711; GO:1904315 28085 XM_044308758.1 14 0 0 1 1 NA NA NA NA NA NA 28086 XM_044321025.1 49 0 94 65 77 NA NA NA NA NA NA 28087 XR_006392845.1 2096 1696 1133 1315 1219 Q9QYC0 2.7e-69 Alpha-adducin (Erythrocyte adducin subunit alpha) Mus musculus (Mouse) actin filament bundle assembly [GO:0051017]; barbed-end actin filament capping [GO:0051016]; cell morphogenesis [GO:0000902]; cell volume homeostasis [GO:0006884]; cellular response to calcium ion [GO:0071277]; cellular response to retinoic acid [GO:0071300]; erythrocyte differentiation [GO:0030218]; hemoglobin metabolic process [GO:0020027]; homeostasis of number of cells within a tissue [GO:0048873]; in utero embryonic development [GO:0001701]; multicellular organism growth [GO:0035264]; negative regulation of actin filament polymerization [GO:0030837]; positive regulation of adherens junction organization [GO:1903393]; positive regulation of angiogenesis [GO:0045766]; positive regulation of endocytosis [GO:0045807]; positive regulation of establishment of endothelial barrier [GO:1903142]; positive regulation of protein binding [GO:0032092] GO:0000902; GO:0001701; GO:0005200; GO:0005516; GO:0005634; GO:0005654; GO:0005737; GO:0005856; GO:0005886; GO:0005912; GO:0006884; GO:0008290; GO:0014069; GO:0016020; GO:0016604; GO:0020027; GO:0030218; GO:0030425; GO:0030507; GO:0030837; GO:0032092; GO:0035264; GO:0042608; GO:0042803; GO:0043197; GO:0045202; GO:0045766; GO:0045807; GO:0046982; GO:0048471; GO:0048873; GO:0051015; GO:0051016; GO:0051017; GO:0061629; GO:0071277; GO:0071300; GO:1903142; GO:1903393 28088 XM_044314165.1 0 4 0 69 0 Q91ZV3 2.26e-24 Discoidin, CUB and LCCL domain-containing protein 2 (Endothelial and smooth muscle cell-derived neuropilin-like protein) Mus musculus (Mouse) negative regulation of cell growth [GO:0030308]; wound healing [GO:0042060] GO:0005886; GO:0009986; GO:0030308; GO:0038023; GO:0042060 28089 XM_029357423.2 30 119 11 27 28 NA NA NA NA NA NA 28090 XM_029339000.2 0 2 1 0 6 NA NA NA NA NA NA 28091 XR_003828154.2 14 19 33 19 117 F7B113 2.87e-116 Sodium/hydrogen exchanger 9 (Na(+)/H(+) exchanger 9) (NHE-9) (Sodium/hydrogen exchanger) (Solute carrier family 9 member 9) Equus caballus (Horse) potassium ion transmembrane transport [GO:0071805]; proton transmembrane transport [GO:1902600]; regulation of intracellular pH [GO:0051453]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725] GO:0005886; GO:0010008; GO:0015385; GO:0015386; GO:0035725; GO:0042803; GO:0051453; GO:0055037; GO:0071805; GO:0098719; GO:1902600 28092 XR_003828154.2 14 19 33 19 117 F7B113 2.87e-116 Sodium/hydrogen exchanger 9 (Na(+)/H(+) exchanger 9) (NHE-9) (Sodium/hydrogen exchanger) (Solute carrier family 9 member 9) Equus caballus (Horse) potassium ion transmembrane transport [GO:0071805]; proton transmembrane transport [GO:1902600]; regulation of intracellular pH [GO:0051453]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725] GO:0005886; GO:0010008; GO:0015385; GO:0015386; GO:0035725; GO:0042803; GO:0051453; GO:0055037; GO:0071805; GO:0098719; GO:1902600 28093 XR_003828154.2 14 19 33 19 117 F7B113 2.87e-116 Sodium/hydrogen exchanger 9 (Na(+)/H(+) exchanger 9) (NHE-9) (Sodium/hydrogen exchanger) (Solute carrier family 9 member 9) Equus caballus (Horse) potassium ion transmembrane transport [GO:0071805]; proton transmembrane transport [GO:1902600]; regulation of intracellular pH [GO:0051453]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725] GO:0005886; GO:0010008; GO:0015385; GO:0015386; GO:0035725; GO:0042803; GO:0051453; GO:0055037; GO:0071805; GO:0098719; GO:1902600 28094 XM_029351151.2 874 419 345 531 1316 Q80T21 5.08e-118 ADAMTS-like protein 4 (ADAMTSL-4) (Thrombospondin repeat-containing protein 1) Mus musculus (Mouse) apoptotic process [GO:0006915]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; pigment cell development [GO:0070285]; positive regulation of apoptotic process [GO:0043065] GO:0002020; GO:0002064; GO:0005576; GO:0005614; GO:0006915; GO:0030198; GO:0031012; GO:0042802; GO:0043065; GO:0070285 28095 XM_044321142.1 18 0 0 0 33 Q9U6Y6 7.68e-112 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 28096 XM_029325882.2 6 0 0 0 0 NA NA NA NA NA NA 28097 XM_029332186.2 1479 1249 753 1282 817 Q5TYV0 8.67e-56 ER membrane protein complex subunit 7 Danio rerio (Zebrafish) (Brachydanio rerio) protein insertion into ER membrane by stop-transfer membrane-anchor sequence [GO:0045050]; tail-anchored membrane protein insertion into ER membrane [GO:0071816] GO:0005789; GO:0016020; GO:0030246; GO:0045050; GO:0071816; GO:0072546 28098 XM_044318541.1 1355 1049 710 1259 1126 O94431 1.74e-38 Hercynylcysteine sulfoxide lyase (EC 4.4.1.-) (Ergothioneine biosynthesis protein 2) (PLP-binding cysteine desulfurase) (PLP-dependent C-S lyase) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) ergothioneine biosynthetic process [GO:0052699]; selenoneine biosynthetic process [GO:1903257] GO:0005634; GO:0005829; GO:0052699; GO:1903257; GO:1990411; GO:1990412 28099 XR_006396433.1 0 7 17 170 42 Q8K2X2 1.82e-23 RNA-binding protein 48 Mus musculus (Mouse) NA GO:0003723; GO:0005654 28100 XM_044323762.1 3 0 31 42 137 Q6MHJ5 2.55e-25 ATP-dependent DNA helicase pif1 (EC 3.6.4.12) Bdellovibrio bacteriovorus (strain ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100) DNA recombination [GO:0006310]; DNA repair [GO:0006281]; telomere maintenance [GO:0000723] GO:0000723; GO:0003677; GO:0003678; GO:0005524; GO:0006281; GO:0006310; GO:0016887 28101 XR_006394483.1 94 25 56 59 189 NA NA NA NA NA NA 28102 XM_029331583.2 27 18 14 0 10 NA NA NA NA NA NA 28103 XR_003823612.2 54 0 0 10 1 NA NA NA NA NA NA 28104 XM_029326979.2 1164 722 454 488 122 Q9UJX0 5.17e-122 Oxidative stress-induced growth inhibitor 1 (Bone marrow stromal cell-derived growth inhibitor) (BMSC-derived growth inhibitor) (Ovary, kidney and liver protein 38) (huOKL38) (Pregnancy-induced growth inhibitor OKL38) Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of cell growth [GO:0030308]; regulation of apoptotic process [GO:0042981]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127] GO:0008083; GO:0030154; GO:0030308; GO:0030334; GO:0042127; GO:0042981 28105 XR_006395624.1 0 0 0 0 104 NA NA NA NA NA NA 28106 XM_044311059.1 140 21 44 24 21 Q54H45 8.84e-27 Probable serine/threonine-protein kinase drkB (EC 2.7.11.1) (Receptor-like kinase 2) (Receptor-like kinase B) (Vesicle-associated receptor tyrosine kinase-like protein 2) Dictyostelium discoideum (Social amoeba) protein phosphorylation [GO:0006468]; signal transduction [GO:0007165] GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0006468; GO:0007165; GO:0016020; GO:0106310 28107 XM_044315359.1 0 8 27 4 2 NA NA NA NA NA NA 28108 XM_029337214.2 271 692 219 269 53 Q8IV35 5.36e-99 WD repeat-containing protein 49 Homo sapiens (Human) NA NA 28109 XM_029349793.2 107 35 46 54 85 Q9NYP7 5.49e-31 Elongation of very long chain fatty acids protein 5 (EC 2.3.1.199) (3-keto acyl-CoA synthase ELOVL5) (ELOVL fatty acid elongase 5) (ELOVL FA elongase 5) (Fatty acid elongase 1) (hELO1) (Very long chain 3-ketoacyl-CoA synthase 5) (Very long chain 3-oxoacyl-CoA synthase 5) Homo sapiens (Human) alpha-linolenic acid metabolic process [GO:0036109]; fatty acid elongation, monounsaturated fatty acid [GO:0034625]; fatty acid elongation, polyunsaturated fatty acid [GO:0034626]; fatty acid elongation, saturated fatty acid [GO:0019367]; linoleic acid metabolic process [GO:0043651]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; positive regulation of fatty acid biosynthetic process [GO:0045723]; sphingolipid biosynthetic process [GO:0030148]; unsaturated fatty acid biosynthetic process [GO:0006636]; very long-chain fatty acid biosynthetic process [GO:0042761] GO:0005783; GO:0005789; GO:0006636; GO:0009922; GO:0016020; GO:0019367; GO:0030148; GO:0030425; GO:0034625; GO:0034626; GO:0035338; GO:0036109; GO:0042761; GO:0043025; GO:0043651; GO:0045723; GO:0097447; GO:0102756 28110 XM_029330696.2 1894 858 941 1749 1759 O61585 0 Katanin p80 WD40 repeat-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin) Strongylocentrotus purpuratus (Purple sea urchin) cell cycle [GO:0007049]; cell division [GO:0051301]; microtubule depolymerization [GO:0007019]; microtubule severing [GO:0051013] GO:0000922; GO:0005737; GO:0005813; GO:0005819; GO:0005874; GO:0007019; GO:0007049; GO:0008017; GO:0008352; GO:0051013; GO:0051301 28111 XM_044312027.1 12 0 13 17 15 NA NA NA NA NA NA 28112 XM_029339397.2 4357 2175 2222 3955 2245 Q05B92 3.01e-54 Transcription factor E3 Bos taurus (Bovine) adaptive immune response [GO:0002250]; humoral immune response [GO:0006959]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell adhesion [GO:0045785]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of osteoclast differentiation [GO:0045670]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000976; GO:0000978; GO:0000981; GO:0001228; GO:0002250; GO:0003700; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006357; GO:0006959; GO:0045670; GO:0045785; GO:0045893; GO:0045944; GO:0046983; GO:0090336 28113 XR_006395993.1 638 1113 518 694 294 NA NA NA NA NA NA 28114 XM_029336845.2 644 553 449 701 710 NA NA NA NA NA NA 28115 XM_029345002.2 96 105 58 162 160 NA NA NA NA NA NA 28116 XM_044316648.1 1247 439 824 764 707 Q9Y4D2 2.49e-131 Diacylglycerol lipase-alpha (DAGL-alpha) (DGL-alpha) (EC 3.1.1.116) (Neural stem cell-derived dendrite regulator) (Sn1-specific diacylglycerol lipase alpha) Homo sapiens (Human) arachidonic acid metabolic process [GO:0019369]; diacylglycerol catabolic process [GO:0046340]; endocannabinoid signaling pathway [GO:0071926]; G protein-coupled glutamate receptor signaling pathway [GO:0007216]; lipid catabolic process [GO:0016042]; neuroblast proliferation [GO:0007405]; neurogenesis [GO:0022008]; neurotransmitter biosynthetic process [GO:0042136]; regulation of neuroinflammatory response [GO:0150077]; retrograde trans-synaptic signaling by endocannabinoid [GO:0098921] GO:0004465; GO:0004806; GO:0005737; GO:0005886; GO:0007216; GO:0007405; GO:0016042; GO:0016298; GO:0019369; GO:0022008; GO:0031901; GO:0032590; GO:0032591; GO:0042136; GO:0043196; GO:0045211; GO:0046340; GO:0046872; GO:0047372; GO:0071926; GO:0098839; GO:0098921; GO:0150077 28117 XM_029336985.2 127 87 107 74 75 NA NA NA NA NA NA 28118 XM_044328321.1 91 42 41 145 51 Q8BGA7 1.31e-37 Integrator complex subunit 15 Mus musculus (Mouse) NA GO:0032039 28119 XM_044318736.1 645 463 477 697 699 NA NA NA NA NA NA 28120 XM_029324688.2 1144 680 665 839 999 NA NA NA NA NA NA 28121 XM_044313732.1 0 36 0 45 18 NA NA NA NA NA NA 28122 XM_044307285.1 38 56 7 4 24 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 28123 XM_044307285.1 38 56 7 4 24 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 28124 XM_044307285.1 38 56 7 4 24 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 28125 XM_044307285.1 38 56 7 4 24 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 28126 XM_044307285.1 38 56 7 4 24 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 28127 XM_044307285.1 38 56 7 4 24 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 28128 XM_044307285.1 38 56 7 4 24 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 28129 XM_044307285.1 38 56 7 4 24 P07207 2.94e-172 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 28130 XM_044307285.1 38 56 7 4 24 P07207 1.4e-135 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 28131 XR_006396520.1 1693 1271 1140 2534 2765 NA NA NA NA NA NA 28132 XM_044311117.1 0 35 4 12 0 NA NA NA NA NA NA 28133 XM_029358606.2 215 298 101 92 55 P59055 6.3e-30 Cysteine/serine-rich nuclear protein 3 (CSRNP-3) (Protein FAM130A2) (TGF-beta-induced apoptosis protein 2) (TAIP-2) Mus musculus (Mouse) apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000981; GO:0001228; GO:0003700; GO:0005634; GO:0006357; GO:0006915; GO:0043065; GO:0043565; GO:0045944 28134 XM_029336022.2 41 16 24 16 32 Q9Y4F3 1.24e-139 Meiosis regulator and mRNA stability factor 1 (Limkain-b1) (Meiosis arrest female protein 1) Homo sapiens (Human) double-strand break repair [GO:0006302]; female meiotic nuclear division [GO:0007143]; oogenesis [GO:0048477]; regulation of gene expression [GO:0010468] GO:0004540; GO:0005737; GO:0005777; GO:0005794; GO:0006302; GO:0007143; GO:0010468; GO:0016020; GO:0043231; GO:0048477; GO:1903231; GO:1905762 28135 XM_029336022.2 41 16 24 16 32 Q9Y4F3 1.01e-34 Meiosis regulator and mRNA stability factor 1 (Limkain-b1) (Meiosis arrest female protein 1) Homo sapiens (Human) double-strand break repair [GO:0006302]; female meiotic nuclear division [GO:0007143]; oogenesis [GO:0048477]; regulation of gene expression [GO:0010468] GO:0004540; GO:0005737; GO:0005777; GO:0005794; GO:0006302; GO:0007143; GO:0010468; GO:0016020; GO:0043231; GO:0048477; GO:1903231; GO:1905762 28136 XM_029324635.2 9 40 11 65 62 F1R332 1.86e-27 Galanin receptor 2a Danio rerio (Zebrafish) (Brachydanio rerio) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; neuropeptide signaling pathway [GO:0007218] GO:0004966; GO:0005886; GO:0007188; GO:0007218; GO:0008528 28137 XM_029356552.2 0 0 13 0 0 Q86U44 2.27e-176 N6-adenosine-methyltransferase catalytic subunit (EC 2.1.1.348) (Methyltransferase-like protein 3) (hMETTL3) (N6-adenosine-methyltransferase 70 kDa subunit) (MT-A70) Homo sapiens (Human) adenosine to inosine editing [GO:0006382]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; circadian rhythm [GO:0007623]; dosage compensation by inactivation of X chromosome [GO:0009048]; endothelial to hematopoietic transition [GO:0098508]; forebrain radial glial cell differentiation [GO:0021861]; gliogenesis [GO:0042063]; innate immune response [GO:0045087]; mRNA catabolic process [GO:0006402]; mRNA destabilization [GO:0061157]; mRNA methylation [GO:0080009]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; oogenesis [GO:0048477]; positive regulation of cap-independent translational initiation [GO:1903679]; positive regulation of translation [GO:0045727]; primary miRNA processing [GO:0031053]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of meiotic cell cycle [GO:0051445]; regulation of T cell differentiation [GO:0045580]; RNA methylation [GO:0001510]; spermatogenesis [GO:0007283]; stem cell population maintenance [GO:0019827] GO:0000398; GO:0001510; GO:0001734; GO:0003729; GO:0005634; GO:0005654; GO:0005737; GO:0006382; GO:0006397; GO:0006402; GO:0006974; GO:0007283; GO:0007623; GO:0008168; GO:0008173; GO:0009048; GO:0016422; GO:0016607; GO:0019827; GO:0021861; GO:0031053; GO:0034644; GO:0036396; GO:0042063; GO:0045087; GO:0045580; GO:0045727; GO:0045746; GO:0046982; GO:0048477; GO:0051445; GO:0060339; GO:0061157; GO:0080009; GO:0098508; GO:1902036; GO:1903679; GO:1904047 28138 XM_029349700.2 715 852 816 794 627 NA NA NA NA NA NA 28139 XM_029352037.2 315 203 152 254 401 Q9Y383 4.71e-87 Putative RNA-binding protein Luc7-like 2 Homo sapiens (Human) mRNA splice site selection [GO:0006376] GO:0003723; GO:0003729; GO:0005685; GO:0006376; GO:0016607; GO:0019899; GO:0071004 28140 XM_044315461.1 9 0 2 12 22 P36887 5.2e-36 cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11) Sus scrofa (Pig) cellular response to heat [GO:0034605]; negative regulation of meiotic cell cycle process involved in oocyte maturation [GO:1904145]; protein phosphorylation [GO:0006468] GO:0001669; GO:0004674; GO:0004679; GO:0004691; GO:0005524; GO:0005634; GO:0005737; GO:0005739; GO:0005886; GO:0006468; GO:0034605; GO:0036126; GO:0042585; GO:0048471; GO:0106310; GO:1904145 28141 XR_006397076.1 925 540 572 713 1430 NA NA NA NA NA NA 28142 XM_044320500.1 2359 2187 1607 4543 3169 D3ZGB1 6.49e-33 Nuclear factor of activated T-cells 5 (NF-AT5) (T-cell transcription factor NFAT5) Rattus norvegicus (Rat) calcineurin-NFAT signaling cascade [GO:0033173]; cellular response to cytokine stimulus [GO:0071345]; cellular response to DNA damage stimulus [GO:0006974]; positive regulation of gene expression [GO:0010628]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R-loop processing [GO:0062176]; regulation of calcineurin-NFAT signaling cascade [GO:0070884]; regulation of transcription by RNA polymerase II [GO:0006357]; response to osmotic stress [GO:0006970] GO:0000978; GO:0000981; GO:0001228; GO:0003677; GO:0003682; GO:0005634; GO:0005654; GO:0005667; GO:0005694; GO:0005737; GO:0005829; GO:0006357; GO:0006970; GO:0006974; GO:0010628; GO:0033173; GO:0045944; GO:0062176; GO:0070884; GO:0071345; GO:1901224; GO:1904996; GO:1990837 28143 XM_044328396.1 0 0 6 0 0 NA NA NA NA NA NA 28144 XM_044309224.1 229 48 120 47 33 NA NA NA NA NA NA 28145 XM_029326796.2 26 38 14 51 34 Q8N0W4 1.04e-94 Neuroligin-4, X-linked (Neuroligin X) (HNLX) Homo sapiens (Human) adult behavior [GO:0030534]; brainstem development [GO:0003360]; cell-cell junction organization [GO:0045216]; cerebellum development [GO:0021549]; chemical synaptic transmission [GO:0007268]; learning [GO:0007612]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of excitatory postsynaptic potential [GO:0090394]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; organ growth [GO:0035265]; postsynaptic membrane assembly [GO:0097104]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; social behavior [GO:0035176]; synapse organization [GO:0050808]; synaptic vesicle endocytosis [GO:0048488]; vocalization behavior [GO:0071625] GO:0003360; GO:0005886; GO:0007158; GO:0007268; GO:0007612; GO:0009986; GO:0016020; GO:0021549; GO:0030182; GO:0030425; GO:0030534; GO:0031404; GO:0035176; GO:0035265; GO:0038023; GO:0042043; GO:0042803; GO:0045202; GO:0045216; GO:0048488; GO:0050804; GO:0050808; GO:0050839; GO:0060076; GO:0071625; GO:0090394; GO:0097104; GO:0097105; GO:0097110; GO:0098793; GO:0098839; GO:0098983; GO:0098985; GO:0099054; GO:0099634 28146 XM_044327369.1 10 0 0 20 4 NA NA NA NA NA NA 28147 XM_044307290.1 225 350 123 110 0 O54701 3.51e-149 Sodium/potassium/calcium exchanger 2 (Na(+)/K(+)/Ca(2+)-exchange protein 2) (Retinal cone Na-Ca+K exchanger) (Solute carrier family 24 member 2) Rattus norvegicus (Rat) calcium ion import [GO:0070509]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; cellular response to high light intensity [GO:0071486]; establishment of localization in cell [GO:0051649]; ion transmembrane transport [GO:0034220]; learning [GO:0007612]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; neuron cellular homeostasis [GO:0070050]; potassium ion transmembrane transport [GO:0071805]; protein-containing complex assembly [GO:0065003]; sodium ion transmembrane transport [GO:0035725] GO:0005262; GO:0005886; GO:0006816; GO:0006874; GO:0007612; GO:0007613; GO:0008273; GO:0015293; GO:0016020; GO:0034220; GO:0035725; GO:0051649; GO:0060291; GO:0060292; GO:0065003; GO:0070050; GO:0070509; GO:0070588; GO:0071486; GO:0071805; GO:0098703 28148 XM_029342224.2 0 13 0 28 87 P18709 2.2e-35 Vitellogenin-A2 (VTG A2) [Cleaved into: Lipovitellin I; Lipovitellin II; Phosvitin] Xenopus laevis (African clawed frog) NA GO:0005319; GO:0045735 28149 XM_029334556.2 1638 1762 518 1199 789 P46250 2.59e-30 SEC14 cytosolic factor (Phosphatidylinositol/phosphatidylcholine transfer protein) (PI/PC TP) Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) ascospore formation [GO:0030437]; CDP-choline pathway [GO:0006657]; Golgi to plasma membrane protein transport [GO:0043001]; Golgi to vacuole transport [GO:0006896]; Golgi vesicle budding [GO:0048194]; negative regulation of phosphatidylcholine biosynthetic process [GO:2001246]; negative regulation of phosphatidylglycerol biosynthetic process [GO:1901352]; phosphatidylinositol metabolic process [GO:0046488]; post-Golgi vesicle-mediated transport [GO:0006892] GO:0000139; GO:0005794; GO:0005829; GO:0006657; GO:0006892; GO:0006896; GO:0008525; GO:0008526; GO:0030437; GO:0043001; GO:0046488; GO:0048194; GO:1901352; GO:2001246 28150 XM_044327274.1 0 1 1 15 3 NA NA NA NA NA NA 28151 XM_029336506.2 5083 3845 3413 4218 4940 P53762 3.01e-136 Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1-beta) (HIF-1-beta) (HIF1-beta) Mus musculus (Mouse) cell differentiation [GO:0030154]; embryonic placenta development [GO:0001892]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of hormone biosynthetic process [GO:0046886]; positive regulation of protein sumoylation [GO:0033235]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to hypoxia [GO:0001666]; response to toxic substance [GO:0009636] GO:0000978; GO:0000981; GO:0000987; GO:0001666; GO:0001892; GO:0003700; GO:0004879; GO:0005634; GO:0005654; GO:0005667; GO:0005737; GO:0006357; GO:0009636; GO:0010575; GO:0016604; GO:0017162; GO:0030154; GO:0033235; GO:0034751; GO:0034753; GO:0042803; GO:0043565; GO:0043619; GO:0044877; GO:0045893; GO:0045944; GO:0046886; GO:0046982; GO:0061629; GO:0090575; GO:1990837 28152 XM_044316244.1 798 534 449 551 302 Q96PM5 1.56e-90 RING finger and CHY zinc finger domain-containing protein 1 (EC 2.3.2.27) (Androgen receptor N-terminal-interacting protein) (CH-rich-interacting match with PLAG1) (E3 ubiquitin-protein ligase Pirh2) (RING finger protein 199) (RING-type E3 ubiquitin transferase RCHY1) (Zinc finger protein 363) (p53-induced RING-H2 protein) (hPirh2) Homo sapiens (Human) error-free translesion synthesis [GO:0070987]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; protein autoubiquitination [GO:0051865]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000151; GO:0002039; GO:0004842; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006511; GO:0008270; GO:0016567; GO:0016607; GO:0031398; GO:0032436; GO:0042803; GO:0043231; GO:0051865; GO:0061630; GO:0070987 28153 XM_029348874.2 1196 958 602 892 797 Q80ZW0 2.3e-26 Serine/threonine-protein kinase 35 (Serine/threonine-protein kinase 35 L1) (EC 2.7.11.1) Mus musculus (Mouse) autophagy [GO:0006914]; meiotic cell cycle [GO:0051321]; protein phosphorylation [GO:0006468] GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0006468; GO:0006914; GO:0016604; GO:0051321; GO:0106310 28154 XM_029344465.2 0 0 3 0 21 P30937 1.5e-21 Somatostatin receptor type 4 (SS-4-R) (SS4-R) (SS4R) Rattus norvegicus (Rat) cell migration [GO:0016477]; cellular response to glucocorticoid stimulus [GO:0071385]; forebrain development [GO:0030900]; negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0106072]; neuropeptide signaling pathway [GO:0007218]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0004930; GO:0004994; GO:0005737; GO:0005886; GO:0007218; GO:0016477; GO:0030900; GO:0042277; GO:0042923; GO:0043005; GO:0070374; GO:0071385; GO:0090238; GO:0106072 28155 XR_006394082.1 10 2 4 16 18 NA NA NA NA NA NA 28156 XM_029346968.2 437 131 129 324 378 Q2T9W2 1.23e-116 tRNA (guanine(6)-N2)-methyltransferase THUMP3 (EC 2.1.1.256) (THUMP domain-containing protein 3) Bos taurus (Bovine) RNA methylation [GO:0001510]; tRNA processing [GO:0008033] GO:0000049; GO:0001510; GO:0005737; GO:0008033; GO:0008168 28157 XM_044314492.1 5 13 40 34 4 NA NA NA NA NA NA 28158 XM_029335754.2 108 0 19 2 82 O62809 1.45e-33 Orexin receptor type 2 (Ox-2-R) (Ox2-R) (Ox2R) (Hypocretin receptor type 2) Sus scrofa (Pig) circadian sleep/wake cycle process [GO:0022410]; feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; locomotion [GO:0040011]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; regulation of circadian sleep/wake cycle, wakefulness [GO:0010840]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0004930; GO:0005886; GO:0007186; GO:0007200; GO:0007218; GO:0007631; GO:0010840; GO:0016499; GO:0022410; GO:0040011; GO:0051480 28159 XR_006392420.1 0 0 0 6 0 B3EWZ5 5.84e-86 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 28160 XR_006392420.1 0 0 0 6 0 B3EWZ5 2.67e-81 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 28161 XR_006392420.1 0 0 0 6 0 B3EWZ5 9.28e-76 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 28162 XR_006392420.1 0 0 0 6 0 B3EWZ5 2.03e-75 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 28163 XR_006392420.1 0 0 0 6 0 B3EWZ5 8.75e-73 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 28164 XR_006392420.1 0 0 0 6 0 B3EWZ5 3.6e-72 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 28165 XR_006392420.1 0 0 0 6 0 B3EWZ5 6.37e-72 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 28166 XR_006392420.1 0 0 0 6 0 B3EWZ5 2.35e-70 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 28167 XR_006392420.1 0 0 0 6 0 B3EWZ5 3.32e-70 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 28168 XR_006392420.1 0 0 0 6 0 B3EWZ5 9.8e-70 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 28169 XR_006392420.1 0 0 0 6 0 B3EWZ5 6.31e-60 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 28170 XR_006392420.1 0 0 0 6 0 B3EWZ5 1.18e-55 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 28171 XR_006392420.1 0 0 0 6 0 B3EWZ5 3.87e-49 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 28172 XR_006392420.1 0 0 0 6 0 B3EWZ5 8.15e-45 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 28173 XR_006392420.1 0 0 0 6 0 B3EWZ5 6.21e-42 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 28174 XR_006392420.1 0 0 0 6 0 B3EWZ5 2.17e-40 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 28175 XR_006392420.1 0 0 0 6 0 B3EWZ5 2.67e-36 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 28176 XR_006392420.1 0 0 0 6 0 B3EWZ5 9.1e-34 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 28177 XM_029335186.2 4 4 0 6 0 NA NA NA NA NA NA 28178 XM_044322112.1 806 481 381 800 1341 A7YWE4 0 Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial (P5C dehydrogenase) (EC 1.2.1.88) (Aldehyde dehydrogenase family 4 member A1) (L-glutamate gamma-semialdehyde dehydrogenase) Bos taurus (Bovine) proline catabolic process to glutamate [GO:0010133] GO:0003842; GO:0005759; GO:0010133 28179 XM_044317674.1 1074 1088 751 862 939 Q96DM3 0 Regulator of MON1-CCZ1 complex (Colon cancer-associated protein Mic1) (Mic-1) (WD repeat-containing protein 98) Homo sapiens (Human) autophagy [GO:0006914]; regulation of autophagy [GO:0010506] GO:0005765; GO:0006914; GO:0010506; GO:0031902; GO:0035658 28180 XM_044325501.1 79 72 122 84 29 NA NA NA NA NA NA 28181 XR_003825626.2 562 443 323 462 402 NA NA NA NA NA NA 28182 XM_044312308.1 2 16 3 8 10 Q9Z2V5 2.33e-114 Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Histone deacetylase mHDA2) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-) Mus musculus (Mouse) aggresome assembly [GO:0070842]; axonal transport of mitochondrion [GO:0019896]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to misfolded protein [GO:0071218]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to topologically incorrect protein [GO:0035967]; cilium disassembly [GO:0061523]; collateral sprouting [GO:0048668]; dendritic spine morphogenesis [GO:0060997]; epigenetic regulation of gene expression [GO:0040029]; histone deacetylation [GO:0016575]; Hsp90 deacetylation [GO:0070846]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; mitochondrion localization [GO:0051646]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of protein-containing complex disassembly [GO:0043242]; negative regulation of proteolysis [GO:0045861]; negative regulation of transcription by RNA polymerase II [GO:0000122]; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:0061734]; peptidyl-lysine deacetylation [GO:0034983]; polyubiquitinated misfolded protein transport [GO:0070845]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of hydrogen peroxide-mediated programmed cell death [GO:1901300]; positive regulation of mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of tubulin deacetylation [GO:0090044]; protein deacetylation [GO:0006476]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; protein-containing complex disassembly [GO:0032984]; regulation of establishment of protein localization [GO:0070201]; regulation of fat cell differentiation [GO:0045598]; regulation of macroautophagy [GO:0016241]; regulation of mitochondrion organization [GO:0010821]; regulation of protein stability [GO:0031647]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]; response to dexamethasone [GO:0071548]; response to growth factor [GO:0070848]; response to immobilization stress [GO:0035902]; response to misfolded protein [GO:0051788]; tubulin deacetylation [GO:0090042]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] GO:0000118; GO:0000122; GO:0000209; GO:0000978; GO:0001222; GO:0001975; GO:0003779; GO:0004407; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0005829; GO:0005874; GO:0005875; GO:0005901; GO:0006476; GO:0006511; GO:0006515; GO:0006886; GO:0007026; GO:0008013; GO:0008017; GO:0008270; GO:0010634; GO:0010821; GO:0015630; GO:0016234; GO:0016235; GO:0016241; GO:0016575; GO:0019896; GO:0030424; GO:0030425; GO:0031252; GO:0031333; GO:0031593; GO:0031625; GO:0031647; GO:0031648; GO:0032418; GO:0032984; GO:0032991; GO:0033138; GO:0033558; GO:0034983; GO:0035902; GO:0035967; GO:0036064; GO:0040029; GO:0042826; GO:0042903; GO:0043005; GO:0043014; GO:0043025; GO:0043130; GO:0043162; GO:0043204; GO:0043242; GO:0045598; GO:0045861; GO:0048156; GO:0048471; GO:0048487; GO:0048668; GO:0048843; GO:0050775; GO:0051412; GO:0051646; GO:0051787; GO:0051788; GO:0051879; GO:0051968; GO:0060997; GO:0061523; GO:0061734; GO:0070201; GO:0070301; GO:0070840; GO:0070842; GO:0070845; GO:0070846; GO:0070848; GO:0071218; GO:0071374; GO:0071548; GO:0090042; GO:0090044; GO:0098779; GO:1901300; GO:1901984; GO:1903223; GO:1904056; GO:1904115; GO:2000273 28183 XM_044312308.1 2 16 3 8 10 Q9Z2V5 1.4e-103 Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Histone deacetylase mHDA2) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-) Mus musculus (Mouse) aggresome assembly [GO:0070842]; axonal transport of mitochondrion [GO:0019896]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to misfolded protein [GO:0071218]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to topologically incorrect protein [GO:0035967]; cilium disassembly [GO:0061523]; collateral sprouting [GO:0048668]; dendritic spine morphogenesis [GO:0060997]; epigenetic regulation of gene expression [GO:0040029]; histone deacetylation [GO:0016575]; Hsp90 deacetylation [GO:0070846]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; mitochondrion localization [GO:0051646]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of protein-containing complex disassembly [GO:0043242]; negative regulation of proteolysis [GO:0045861]; negative regulation of transcription by RNA polymerase II [GO:0000122]; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:0061734]; peptidyl-lysine deacetylation [GO:0034983]; polyubiquitinated misfolded protein transport [GO:0070845]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of hydrogen peroxide-mediated programmed cell death [GO:1901300]; positive regulation of mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of tubulin deacetylation [GO:0090044]; protein deacetylation [GO:0006476]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; protein-containing complex disassembly [GO:0032984]; regulation of establishment of protein localization [GO:0070201]; regulation of fat cell differentiation [GO:0045598]; regulation of macroautophagy [GO:0016241]; regulation of mitochondrion organization [GO:0010821]; regulation of protein stability [GO:0031647]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]; response to dexamethasone [GO:0071548]; response to growth factor [GO:0070848]; response to immobilization stress [GO:0035902]; response to misfolded protein [GO:0051788]; tubulin deacetylation [GO:0090042]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] GO:0000118; GO:0000122; GO:0000209; GO:0000978; GO:0001222; GO:0001975; GO:0003779; GO:0004407; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0005829; GO:0005874; GO:0005875; GO:0005901; GO:0006476; GO:0006511; GO:0006515; GO:0006886; GO:0007026; GO:0008013; GO:0008017; GO:0008270; GO:0010634; GO:0010821; GO:0015630; GO:0016234; GO:0016235; GO:0016241; GO:0016575; GO:0019896; GO:0030424; GO:0030425; GO:0031252; GO:0031333; GO:0031593; GO:0031625; GO:0031647; GO:0031648; GO:0032418; GO:0032984; GO:0032991; GO:0033138; GO:0033558; GO:0034983; GO:0035902; GO:0035967; GO:0036064; GO:0040029; GO:0042826; GO:0042903; GO:0043005; GO:0043014; GO:0043025; GO:0043130; GO:0043162; GO:0043204; GO:0043242; GO:0045598; GO:0045861; GO:0048156; GO:0048471; GO:0048487; GO:0048668; GO:0048843; GO:0050775; GO:0051412; GO:0051646; GO:0051787; GO:0051788; GO:0051879; GO:0051968; GO:0060997; GO:0061523; GO:0061734; GO:0070201; GO:0070301; GO:0070840; GO:0070842; GO:0070845; GO:0070846; GO:0070848; GO:0071218; GO:0071374; GO:0071548; GO:0090042; GO:0090044; GO:0098779; GO:1901300; GO:1901984; GO:1903223; GO:1904056; GO:1904115; GO:2000273 28184 XM_044319563.1 0 0 0 0 6 Q09575 3.41e-46 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 28185 XR_003825483.2 124 53 11 70 18 NA NA NA NA NA NA 28186 XM_029335810.2 980 987 498 902 906 B5FYQ0 1.15e-73 ADP-ribosylation factor-like protein 3 Taeniopygia guttata (Zebra finch) (Poephila guttata) cilium assembly [GO:0060271]; Golgi to plasma membrane transport [GO:0006893]; intraciliary transport [GO:0042073]; kidney development [GO:0001822]; mitotic cytokinesis [GO:0000281]; photoreceptor cell development [GO:0042461]; protein localization to ciliary membrane [GO:1903441]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]; smoothened signaling pathway [GO:0007224] GO:0000139; GO:0000281; GO:0000287; GO:0001822; GO:0003924; GO:0005525; GO:0005634; GO:0005654; GO:0005794; GO:0005813; GO:0005876; GO:0005881; GO:0005929; GO:0005930; GO:0006893; GO:0007224; GO:0007264; GO:0008017; GO:0015031; GO:0019003; GO:0030496; GO:0032391; GO:0032794; GO:0036064; GO:0042073; GO:0042461; GO:0060271; GO:1903441 28187 XM_044314064.1 1 0 6 31 5 NA NA NA NA NA NA 28188 XR_006393157.1 897 2678 765 1877 4929 Q92051 5.63e-48 Carbonic anhydrase (EC 4.2.1.1) (Carbonate dehydratase) Danio rerio (Zebrafish) (Brachydanio rerio) carbon dioxide transport [GO:0015670]; hypotonic salinity response [GO:0042539]; one-carbon metabolic process [GO:0006730] GO:0004089; GO:0005737; GO:0006730; GO:0008270; GO:0015670; GO:0016836; GO:0042539 28189 XR_006393157.1 897 2678 765 1877 4929 Q92051 5.63e-48 Carbonic anhydrase (EC 4.2.1.1) (Carbonate dehydratase) Danio rerio (Zebrafish) (Brachydanio rerio) carbon dioxide transport [GO:0015670]; hypotonic salinity response [GO:0042539]; one-carbon metabolic process [GO:0006730] GO:0004089; GO:0005737; GO:0006730; GO:0008270; GO:0015670; GO:0016836; GO:0042539 28190 XM_044317041.1 376 521 387 1114 748 Q8R5C8 9.41e-67 Zinc finger MYND domain-containing protein 11 Mus musculus (Mouse) chromatin organization [GO:0006325]; defense response to virus [GO:0051607]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of JNK cascade [GO:0046329]; regulation of signal transduction [GO:0009966]; regulation of transcription elongation by RNA polymerase II [GO:0034243] GO:0003690; GO:0003714; GO:0005634; GO:0005654; GO:0005694; GO:0006325; GO:0008270; GO:0009966; GO:0034243; GO:0035064; GO:0042393; GO:0043124; GO:0046329; GO:0051607; GO:2001237 28191 XM_044325473.1 265 110 68 199 351 Q5ZIJ9 4.86e-98 E3 ubiquitin-protein ligase MIB2 (EC 2.3.2.27) (Mind bomb homolog 2) (RING-type E3 ubiquitin transferase MIB2) Gallus gallus (Chicken) Notch signaling pathway [GO:0007219]; protein ubiquitination [GO:0016567] GO:0004842; GO:0005737; GO:0007219; GO:0008270; GO:0016567 28192 XM_029357248.2 9 2 41 17 112 NA NA NA NA NA NA 28193 XM_029336667.2 1458 576 545 762 881 P97471 0 Mothers against decapentaplegic homolog 4 (MAD homolog 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4 homolog) (SMAD family member 4) (SMAD 4) (Smad4) Mus musculus (Mouse) adrenal gland development [GO:0030325]; aging [GO:0007568]; anatomical structure morphogenesis [GO:0009653]; anterior/posterior pattern specification [GO:0009952]; atrioventricular canal development [GO:0036302]; atrioventricular valve formation [GO:0003190]; axon guidance [GO:0007411]; BMP signaling pathway [GO:0030509]; brainstem development [GO:0003360]; branching involved in ureteric bud morphogenesis [GO:0001658]; cardiac septum development [GO:0003279]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular iron ion homeostasis [GO:0006879]; cellular response to glucose stimulus [GO:0071333]; developmental growth [GO:0048589]; DNA-templated transcription [GO:0006351]; embryonic digit morphogenesis [GO:0042733]; endocardial cell differentiation [GO:0060956]; endoderm development [GO:0007492]; endothelial cell activation [GO:0042118]; epithelial cell migration [GO:0010631]; epithelial to mesenchymal transition [GO:0001837]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; ERK1 and ERK2 cascade [GO:0070371]; female gonad development [GO:0008585]; female gonad morphogenesis [GO:0061040]; formation of anatomical boundary [GO:0048859]; gastrulation [GO:0007369]; gastrulation with mouth forming second [GO:0001702]; in utero embryonic development [GO:0001701]; interleukin-6-mediated signaling pathway [GO:0070102]; intracellular signal transduction [GO:0035556]; kidney development [GO:0001822]; left ventricular cardiac muscle tissue morphogenesis [GO:0003220]; male gonad development [GO:0008584]; mesoderm development [GO:0007498]; metanephric mesenchyme morphogenesis [GO:0072133]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of cardiac myofibril assembly [GO:1905305]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nephrogenic mesenchyme morphogenesis [GO:0072134]; neural crest cell differentiation [GO:0014033]; neuron fate commitment [GO:0048663]; osteoblast differentiation [GO:0001649]; outflow tract septum morphogenesis [GO:0003148]; ovarian follicle development [GO:0001541]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell proliferation involved in heart valve morphogenesis [GO:0003251]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of follicle-stimulating hormone secretion [GO:0046881]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of histone H3-K9 acetylation [GO:2000617]; positive regulation of luteinizing hormone secretion [GO:0033686]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; regulation of binding [GO:0051098]; regulation of cell population proliferation [GO:0042127]; regulation of hair follicle development [GO:0051797]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; regulation of transforming growth factor beta2 production [GO:0032909]; response to hypoxia [GO:0001666]; response to transforming growth factor beta [GO:0071559]; sebaceous gland development [GO:0048733]; secondary palate development [GO:0062009]; seminiferous tubule development [GO:0072520]; single fertilization [GO:0007338]; SMAD protein complex assembly [GO:0007183]; SMAD protein signal transduction [GO:0060395]; somite rostral/caudal axis specification [GO:0032525]; spermatogenesis [GO:0007283]; tissue morphogenesis [GO:0048729]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]; uterus development [GO:0060065]; ventricular septum morphogenesis [GO:0060412]; wound healing [GO:0042060] GO:0000122; GO:0000785; GO:0000976; GO:0000977; GO:0000978; GO:0000981; GO:0001223; GO:0001228; GO:0001541; GO:0001649; GO:0001658; GO:0001666; GO:0001701; GO:0001702; GO:0001822; GO:0001837; GO:0003148; GO:0003190; GO:0003198; GO:0003220; GO:0003251; GO:0003279; GO:0003360; GO:0003677; GO:0003682; GO:0003700; GO:0005518; GO:0005634; GO:0005654; GO:0005667; GO:0005737; GO:0005813; GO:0005829; GO:0006351; GO:0006357; GO:0006366; GO:0006879; GO:0007179; GO:0007183; GO:0007283; GO:0007338; GO:0007369; GO:0007411; GO:0007492; GO:0007498; GO:0007568; GO:0008283; GO:0008285; GO:0008584; GO:0008585; GO:0009653; GO:0009952; GO:0010614; GO:0010631; GO:0010666; GO:0010718; GO:0010862; GO:0014033; GO:0017015; GO:0030154; GO:0030308; GO:0030325; GO:0030509; GO:0030511; GO:0030513; GO:0031005; GO:0032444; GO:0032525; GO:0032909; GO:0032991; GO:0033686; GO:0035556; GO:0036302; GO:0042060; GO:0042118; GO:0042127; GO:0042177; GO:0042733; GO:0042802; GO:0042803; GO:0043199; GO:0043565; GO:0045892; GO:0045893; GO:0045944; GO:0046332; GO:0046872; GO:0046881; GO:0048589; GO:0048663; GO:0048729; GO:0048733; GO:0048859; GO:0051098; GO:0051571; GO:0051797; GO:0060065; GO:0060391; GO:0060395; GO:0060412; GO:0060548; GO:0060956; GO:0061040; GO:0061629; GO:0062009; GO:0070102; GO:0070371; GO:0070373; GO:0070411; GO:0070412; GO:0071141; GO:0071144; GO:0071333; GO:0071559; GO:0072133; GO:0072134; GO:0072520; GO:0090575; GO:1902895; GO:1905305; GO:2000617 28194 XM_044308625.1 0 16 0 0 0 NA NA NA NA NA NA 28195 XM_029334060.2 154 82 122 193 171 Q9NRN9 8.69e-84 rRNA N6-adenosine-methyltransferase METTL5 (EC 2.1.1.-) (Methyltransferase-like protein 5) Homo sapiens (Human) positive regulation of translation [GO:0045727]; rRNA methylation [GO:0031167]; stem cell differentiation [GO:0048863] GO:0003676; GO:0005634; GO:0008988; GO:0016740; GO:0031167; GO:0042995; GO:0045727; GO:0048863; GO:0098793; GO:0098794; GO:1904047 28196 XM_044306767.1 186 39 104 89 62 Q7RTR2 6.59e-69 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 28197 XM_044306767.1 186 39 104 89 62 Q7RTR2 3.25e-64 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 28198 XM_044306767.1 186 39 104 89 62 Q7RTR2 2.84e-61 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 28199 XM_044306767.1 186 39 104 89 62 Q7RTR2 2.32e-56 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 28200 XM_044306767.1 186 39 104 89 62 Q7RTR2 1.64e-47 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 28201 XR_006396384.1 2 0 4 5 41 NA NA NA NA NA NA 28202 XM_029335558.2 0 5 3 9 2 NA NA NA NA NA NA 28203 XM_044320802.1 33 49 42 137 90 NA NA NA NA NA NA 28204 XR_006394741.1 374 67 156 273 309 NA NA NA NA NA NA 28205 XM_044319369.1 0 0 0 7 3 NA NA NA NA NA NA 28206 XM_044319875.1 11 4 4 3 26 NA NA NA NA NA NA 28207 XM_044325782.1 26 1 6 10 16 Q8K3Z0 1.78e-31 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 28208 XM_029356685.2 18 17 0 4 12 P0CT40 3.06e-60 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 28209 XM_029356685.2 18 17 0 4 12 P0CT40 3.06e-60 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 28210 XM_029350214.2 91 281 114 184 111 NA NA NA NA NA NA 28211 XM_044322081.1 0 0 209 0 0 B1AJZ9 2.25e-31 Forkhead-associated domain-containing protein 1 (FHA domain-containing protein 1) Homo sapiens (Human) NA NA 28212 XM_044322081.1 0 0 209 0 0 B1AJZ9 9.74e-29 Forkhead-associated domain-containing protein 1 (FHA domain-containing protein 1) Homo sapiens (Human) NA NA 28213 XM_029340872.2 1096 602 640 586 522 Q2YDD1 1.26e-47 Centrosomal protein 43 (FGFR1 oncogene partner) Bos taurus (Bovine) cell projection organization [GO:0030030]; microtubule anchoring [GO:0034453] GO:0005737; GO:0005814; GO:0030030; GO:0034453; GO:0042995 28214 XM_029340953.2 31348 26514 23076 20888 15649 Q5XI32 1.2e-164 F-actin-capping protein subunit beta (CapZ beta) Rattus norvegicus (Rat) actin polymerization or depolymerization [GO:0008154]; barbed-end actin filament capping [GO:0051016]; cell morphogenesis [GO:0000902]; cell projection organization [GO:0030030]; cytoskeleton organization [GO:0007010]; lamellipodium assembly [GO:0030032]; muscle cell development [GO:0055001]; negative regulation of filopodium assembly [GO:0051490]; regulation of cell morphogenesis [GO:0022604]; regulation of lamellipodium assembly [GO:0010591] GO:0000902; GO:0003779; GO:0005903; GO:0007010; GO:0008154; GO:0008290; GO:0010591; GO:0014069; GO:0016020; GO:0022604; GO:0030017; GO:0030027; GO:0030030; GO:0030032; GO:0030863; GO:0032279; GO:0043025; GO:0043197; GO:0051015; GO:0051016; GO:0051490; GO:0055001; GO:0071203; GO:0097224; GO:0098685; GO:0098686 28215 XM_044318827.1 2829 2258 91 1876 1912 Q5R9T9 2.19e-47 Guanylate-binding protein 6 (EC 3.6.5.-) (GTP-binding protein 6) (GBP-6) (Guanine nucleotide-binding protein 6) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cellular response to type II interferon [GO:0071346]; defense response to bacterium [GO:0042742]; immune response [GO:0006955] GO:0003924; GO:0005525; GO:0006955; GO:0031410; GO:0042742; GO:0071346 28216 XM_029345944.2 284 428 300 259 418 NA NA NA NA NA NA 28217 XM_029347756.2 0 192 0 0 0 P10079 0 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 28218 XM_029347756.2 0 192 0 0 0 P10079 0 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 28219 XM_029347756.2 0 192 0 0 0 P10079 0 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 28220 XM_029347756.2 0 192 0 0 0 P10079 0 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 28221 XM_029347756.2 0 192 0 0 0 P10079 0 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 28222 XM_044309128.1 67 0 0 0 5 NA NA NA NA NA NA 28223 XM_044320826.1 33 0 23 61 39 NA NA NA NA NA NA 28224 XM_029347603.2 90 0 425 0 369 Q8IS64 6.02e-156 Endothelin-converting enzyme homolog (ECE) (EC 3.4.24.-) Locusta migratoria (Migratory locust) proteolysis [GO:0006508] GO:0004175; GO:0004222; GO:0005886; GO:0006508; GO:0008270 28225 XM_029341126.2 44 0 140 48 340 I6V1W0 2.34e-93 Protein brambleberry Danio rerio (Zebrafish) (Brachydanio rerio) karyomere membrane fusion [GO:0061472]; pronuclear fusion [GO:0007344] GO:0007344; GO:0031965; GO:0061472 28226 XM_029333737.2 1511 1477 995 1403 1444 Q8HXY4 2e-168 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial (EC 1.2.4.4) (Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain) (BCKDE1A) (BCKDH E1-alpha) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0003863; GO:0005759; GO:0046872 28227 XM_044319669.1 76 145 44 82 83 NA NA NA NA NA NA 28228 XM_044314246.1 391 265 241 254 749 NA NA NA NA NA NA 28229 XM_029327631.2 4 27 15 0 87 NA NA NA NA NA NA 28230 XM_044323755.1 0 0 5 0 20 NA NA NA NA NA NA 28231 XM_044325956.1 246 105 103 99 314 NA NA NA NA NA NA 28232 XM_044329294.1 0 34 69 111 184 P35234 6.41e-36 Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Neural-specific protein-tyrosine phosphatase) (Striatum-enriched protein-tyrosine phosphatase) (STEP) Rattus norvegicus (Rat) aging [GO:0007568]; exploration behavior [GO:0035640]; negative regulation of MAP kinase activity [GO:0043407]; peptidyl-tyrosine dephosphorylation [GO:0035335]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of receptor internalization [GO:0002092]; positive regulation of response to drug [GO:2001025]; protein dephosphorylation [GO:0006470]; response to acetylsalicylate [GO:1903492]; response to amphetamine [GO:0001975]; response to immobilization stress [GO:0035902]; response to xenobiotic stimulus [GO:0009410]; signal transduction [GO:0007165] GO:0001784; GO:0001934; GO:0001975; GO:0002092; GO:0004725; GO:0005783; GO:0005829; GO:0005886; GO:0006470; GO:0007165; GO:0007568; GO:0008021; GO:0009410; GO:0010976; GO:0016020; GO:0019901; GO:0030054; GO:0030424; GO:0035254; GO:0035335; GO:0035640; GO:0035902; GO:0042307; GO:0042802; GO:0043025; GO:0043204; GO:0043407; GO:0051019; GO:0097060; GO:1900273; GO:1901216; GO:1903492; GO:1903955; GO:1990635; GO:2001025 28233 XM_044318033.1 26 4 40 59 320 NA NA NA NA NA NA 28234 XM_044318909.1 9 62 4 4 12 F1NV61 2.94e-71 Caspase-7 (CASP-7) (EC 3.4.22.60) [Cleaved into: Caspase-7 subunit p20; Caspase-7 subunit p11] Gallus gallus (Chicken) apoptotic process [GO:0006915]; defense response to bacterium [GO:0042742]; execution phase of apoptosis [GO:0097194]; lymphocyte apoptotic process [GO:0070227]; positive regulation of plasma membrane repair [GO:1905686]; proteolysis [GO:0006508] GO:0003723; GO:0004190; GO:0005615; GO:0005634; GO:0005737; GO:0005829; GO:0006508; GO:0006915; GO:0042742; GO:0070227; GO:0097153; GO:0097194; GO:0097200; GO:1905686 28235 XM_029343639.2 2102 1853 1290 1951 3099 O77562 1.43e-39 Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1-related transcriptional regulator) (NUDR) Pan troglodytes (Chimpanzee) embryonic skeletal system development [GO:0048706]; neural tube closure [GO:0001843]; regulation of mammary gland epithelial cell proliferation [GO:0033599]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000981; GO:0001843; GO:0003677; GO:0005634; GO:0006357; GO:0033599; GO:0046872; GO:0048706 28236 XM_044315254.1 16 2 1 3 24 NA NA NA NA NA NA 28237 XM_044312187.1 17 23 0 10 21 NA NA NA NA NA NA 28238 XM_044324407.1 14 4 0 2 22 NA NA NA NA NA NA 28239 XM_029343310.2 510 320 278 577 277 Q5PR73 2.41e-25 GTP-binding protein Di-Ras2 (Distinct subgroup of the Ras family member 2) Mus musculus (Mouse) signal transduction [GO:0007165] GO:0003924; GO:0005525; GO:0005886; GO:0007165; GO:0019003 28240 XM_029330384.2 7 14 15 3 27 NA NA NA NA NA NA 28241 XM_029340748.2 414 76 241 230 569 Q6AX59 5.55e-70 Protein ABHD8 (EC 3.-.-.-) (Alpha/beta hydrolase domain-containing protein 8) (Abhydrolase domain-containing protein 8) Xenopus laevis (African clawed frog) NA GO:0016787 28242 XM_029332234.2 1442 1171 916 1417 1128 Q8R3S6 0 Exocyst complex component 1 (Exocyst complex component Sec3) Mus musculus (Mouse) embryo implantation [GO:0007566]; exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; membrane fission [GO:0090148]; mitotic cytokinesis [GO:0000281]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of protein secretion [GO:0050714]; protein transport [GO:0015031]; vesicle docking involved in exocytosis [GO:0006904]; vesicle tethering involved in exocytosis [GO:0090522] GO:0000145; GO:0000281; GO:0005546; GO:0005737; GO:0005886; GO:0006887; GO:0006893; GO:0006904; GO:0007566; GO:0015031; GO:0048015; GO:0048471; GO:0050714; GO:0090148; GO:0090522; GO:0090543; GO:0098592 28243 XM_044329287.1 8 12 12 2 0 NA NA NA NA NA NA 28244 XM_044320828.1 0 0 17 1 23 NA NA NA NA NA NA 28245 XM_044316218.1 0 0 0 0 148 Q6IPM2 1.13e-31 IQ domain-containing protein E Homo sapiens (Human) limb morphogenesis [GO:0035108] GO:0005929; GO:0035108; GO:0060170 28246 XM_029326355.2 0 0 11 32 100 NA NA NA NA NA NA 28247 XM_029343045.2 701 881 420 628 644 Q56P03 5.2e-41 E2F-associated phosphoprotein (EAPP) Homo sapiens (Human) negative regulation of transcription elongation by RNA polymerase II [GO:0034244]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968] GO:0005634; GO:0005737; GO:0008284; GO:0032968; GO:0034244 28248 XM_029334993.2 228 34 103 77 77 Q9H0G5 8.39e-43 Nuclear speckle splicing regulatory protein 1 (Coiled-coil domain-containing protein 55) (Nuclear speckle-related protein 70) (NSrp70) Homo sapiens (Human) developmental process [GO:0032502]; in utero embryonic development [GO:0001701]; mRNA processing [GO:0006397]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380] GO:0000381; GO:0001701; GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0006397; GO:0008380; GO:0016607; GO:0032502; GO:1990904 28249 XM_029356735.2 533 514 621 408 359 Q9DB28 7.21e-34 Ribonuclease P/MRP protein subunit POP5 Mus musculus (Mouse) rRNA processing [GO:0006364]; tRNA 5'-leader removal [GO:0001682]; tRNA processing [GO:0008033] GO:0000171; GO:0000172; GO:0001682; GO:0004526; GO:0005655; GO:0005730; GO:0006364; GO:0008033; GO:0030681; GO:0033204 28250 XM_044323813.1 134 77 109 271 391 NA NA NA NA NA NA 28251 XR_006393192.1 12 9 19 14 29 NA NA NA NA NA NA 28252 XM_029331317.2 252 69 91 62 153 NA NA NA NA NA NA 28253 XM_029340359.2 2172 1887 716 1258 1632 Q52I78 0 Nicotinamide phosphoribosyltransferase (NAmPRTase) (Nampt) (EC 2.4.2.12) (Pre-B-cell colony-enhancing factor 1 homolog) (PBEF) (Visfatin) Sus scrofa (Pig) circadian regulation of gene expression [GO:0032922]; NAD biosynthetic process [GO:0009435] GO:0005125; GO:0005615; GO:0005634; GO:0005737; GO:0009435; GO:0032922; GO:0047280 28254 XR_006394362.1 0 0 0 15 8 NA NA NA NA NA NA 28255 XR_006393682.1 115 71 74 140 134 NA NA NA NA NA NA 28256 XR_006393410.1 32 33 66 114 733 NA NA NA NA NA NA 28257 XM_029353472.2 316 422 134 494 506 NA NA NA NA NA NA 28258 XM_029333446.2 151 222 238 714 633 Q6UWX4 1.13e-165 HHIP-like protein 2 Homo sapiens (Human) NA GO:0005576 28259 XM_044327360.1 25 30 11 58 39 NA NA NA NA NA NA 28260 XM_029335324.2 2 0 19 4 9 NA NA NA NA NA NA 28261 XM_029337690.2 5490 5997 3563 3803 2301 O95562 8.32e-50 Vesicle transport protein SFT2B (SFT2 domain-containing protein 2) Homo sapiens (Human) protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] GO:0015031; GO:0016020; GO:0016192; GO:0070062 28262 XM_044317977.1 480 636 386 407 868 Q7TQH0 3.93e-28 Ataxin-2-like protein Mus musculus (Mouse) mRNA metabolic process [GO:0016071]; stress granule assembly [GO:0034063] GO:0003723; GO:0005829; GO:0010494; GO:0016020; GO:0016071; GO:0016607; GO:0034063 28263 XM_044311962.1 0 14 0 10 9 NA NA NA NA NA NA 28264 XM_029326891.2 172 122 138 200 180 NA NA NA NA NA NA 28265 XM_044325429.1 18 4 26 20 47 NA NA NA NA NA NA 28266 XM_029328884.2 719 529 467 689 927 Q8CE50 6.84e-91 Sorting nexin-30 Mus musculus (Mouse) autophagy of mitochondrion [GO:0000422]; endocytic recycling [GO:0032456]; piecemeal microautophagy of the nucleus [GO:0034727]; positive regulation of autophagosome assembly [GO:2000786]; protein transport [GO:0015031]; reticulophagy [GO:0061709] GO:0000407; GO:0000422; GO:0005769; GO:0015031; GO:0031901; GO:0032456; GO:0034727; GO:0035091; GO:0061709; GO:2000786 28267 XM_029333795.2 1124 1412 897 772 738 Q969Q6 0 Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma (Protein phosphatase subunit G5PR) (Rhabdomyosarcoma antigen MU-RMS-40.6A/6C) Homo sapiens (Human) activation of protein kinase activity [GO:0032147]; B cell homeostasis [GO:0001782]; cortical cytoskeleton organization [GO:0030865]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of B cell differentiation [GO:0045579]; regulation of antimicrobial humoral response [GO:0002759]; regulation of dephosphorylation [GO:0035303]; regulation of mitochondrial depolarization [GO:0051900]; spleen development [GO:0048536]; T cell homeostasis [GO:0043029] GO:0000226; GO:0001782; GO:0002759; GO:0005654; GO:0005794; GO:0005813; GO:0005829; GO:0030865; GO:0032147; GO:0035303; GO:0043029; GO:0045579; GO:0046872; GO:0048536; GO:0051900 28268 XM_029341197.2 98 33 32 67 62 O62852 3.91e-110 Short transient receptor potential channel 5 (Rtrp5) (TrpC5) (Capacitative calcium entry channel 2) (CCE2) Oryctolagus cuniculus (Rabbit) neuron apoptotic process [GO:0051402]; phosphatidylserine exposure on apoptotic cell surface [GO:0070782] GO:0005262; GO:0005886; GO:0034704; GO:0051402; GO:0070679; GO:0070782 28269 XM_029349643.2 39 53 40 75 11 NA NA NA NA NA NA 28270 XM_029329301.2 57 59 42 56 12 NA NA NA NA NA NA 28271 XM_044321422.1 0 9 0 0 4 Q91ZI0 6.85e-65 Cadherin EGF LAG seven-pass G-type receptor 3 Mus musculus (Mouse) axonal fasciculation [GO:0007413]; cell-cell adhesion [GO:0098609]; cilium assembly [GO:0060271]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; planar cell polarity pathway involved in axon guidance [GO:1904938]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] GO:0001932; GO:0004930; GO:0005509; GO:0005886; GO:0007156; GO:0007413; GO:0032880; GO:0036514; GO:0036515; GO:0060271; GO:0097475; GO:0098609; GO:1904938 28272 XM_044321422.1 0 9 0 0 4 Q91ZI0 4.49e-45 Cadherin EGF LAG seven-pass G-type receptor 3 Mus musculus (Mouse) axonal fasciculation [GO:0007413]; cell-cell adhesion [GO:0098609]; cilium assembly [GO:0060271]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; planar cell polarity pathway involved in axon guidance [GO:1904938]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] GO:0001932; GO:0004930; GO:0005509; GO:0005886; GO:0007156; GO:0007413; GO:0032880; GO:0036514; GO:0036515; GO:0060271; GO:0097475; GO:0098609; GO:1904938 28273 XM_044321422.1 0 9 0 0 4 Q91ZI0 1.1e-37 Cadherin EGF LAG seven-pass G-type receptor 3 Mus musculus (Mouse) axonal fasciculation [GO:0007413]; cell-cell adhesion [GO:0098609]; cilium assembly [GO:0060271]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; planar cell polarity pathway involved in axon guidance [GO:1904938]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] GO:0001932; GO:0004930; GO:0005509; GO:0005886; GO:0007156; GO:0007413; GO:0032880; GO:0036514; GO:0036515; GO:0060271; GO:0097475; GO:0098609; GO:1904938 28274 XM_044321422.1 0 9 0 0 4 Q91ZI0 7.11e-33 Cadherin EGF LAG seven-pass G-type receptor 3 Mus musculus (Mouse) axonal fasciculation [GO:0007413]; cell-cell adhesion [GO:0098609]; cilium assembly [GO:0060271]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; planar cell polarity pathway involved in axon guidance [GO:1904938]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] GO:0001932; GO:0004930; GO:0005509; GO:0005886; GO:0007156; GO:0007413; GO:0032880; GO:0036514; GO:0036515; GO:0060271; GO:0097475; GO:0098609; GO:1904938 28275 XR_006394914.1 217 279 165 230 316 NA NA NA NA NA NA 28276 XM_044320873.1 3151 2754 1647 1685 2694 E2RQ08 0 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (Ribophorin I) (RPN-I) (Ribophorin-1) Canis lupus familiaris (Dog) (Canis familiaris) protein glycosylation [GO:0006486]; protein N-linked glycosylation via asparagine [GO:0018279] GO:0005791; GO:0005829; GO:0006486; GO:0008250; GO:0018279 28277 XM_044322496.1 25 9 12 13 4 NA NA NA NA NA NA 28278 XM_029344746.2 97 279 61 105 133 Q9P209 5.04e-70 Centrosomal protein of 72 kDa (Cep72) Homo sapiens (Human) centriole replication [GO:0007099]; gamma-tubulin complex localization [GO:0033566]; regulation of protein localization to centrosome [GO:1904779]; spindle organization [GO:0007051] GO:0005654; GO:0005739; GO:0005813; GO:0005829; GO:0007051; GO:0007099; GO:0033566; GO:0034451; GO:1904779 28279 XM_044311173.1 0 53 74 0 0 NA NA NA NA NA NA 28280 XM_029333959.2 510 879 791 415 394 A0A061IR73 0 Peroxisomal ATPase PEX6 (EC 3.6.4.-) (Peroxin-6) (Peroxisomal biogenesis factor 6) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) protein import into peroxisome matrix [GO:0016558]; protein import into peroxisome matrix, receptor recycling [GO:0016562]; protein import into peroxisome matrix, translocation [GO:0016561]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335] GO:0001750; GO:0005524; GO:0005778; GO:0005829; GO:0008022; GO:0016558; GO:0016561; GO:0016562; GO:0016887; GO:0043335; GO:0044877; GO:0050821; GO:0140036; GO:0140318 28281 XM_029339806.2 5301 3525 1887 3419 2373 NA NA NA NA NA NA 28282 XM_044308384.1 0 37 207 2 6 NA NA NA NA NA NA 28283 XM_029355897.2 595 526 459 2173 950 Q80TE0 0 RNA polymerase II-associated protein 1 Mus musculus (Mouse) transcription by RNA polymerase II [GO:0006366] GO:0000428; GO:0003677; GO:0005634; GO:0006366; GO:0016779; GO:0030880 28284 XM_044318435.1 0 0 0 0 15 NA NA NA NA NA NA 28285 XM_029343567.2 250 128 107 135 175 O57314 1.09e-86 Very-long-chain 3-oxoacyl-CoA reductase (EC 1.1.1.330) (17-beta-hydroxysteroid dehydrogenase 12) (17-beta-HSD 12) (3-ketoacyl-CoA reductase) (KAR) (Estradiol 17-beta-dehydrogenase 12) (EC 1.1.1.62) Anas platyrhynchos (Mallard) (Anas boschas) estrogen biosynthetic process [GO:0006703]; fatty acid biosynthetic process [GO:0006633] GO:0005789; GO:0006633; GO:0006703; GO:0044594; GO:0102339; GO:0102340; GO:0102341; GO:0102342 28286 XM_044320521.1 7 1 1 0 1 A0JPE1 1.8e-23 Divergent protein kinase domain 1B (Protein FAM69B) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005789 28287 XM_029350025.2 500 484 361 584 293 Q2ABP2 3.13e-49 Post-GPI attachment to proteins factor 2 (FGF receptor-activating protein 1) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) GPI anchor biosynthetic process [GO:0006506] GO:0000139; GO:0005789; GO:0006506 28288 XM_029339035.2 22 3 0 0 0 NA NA NA NA NA NA 28289 XM_044315081.1 17 0 8 0 10 NA NA NA NA NA NA 28290 XM_029337766.2 157 166 82 141 121 Q13114 1.45e-30 TNF receptor-associated factor 3 (EC 2.3.2.27) (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein 1) (LAP1) (RING-type E3 ubiquitin transferase TRAF3) Homo sapiens (Human) apoptotic process [GO:0006915]; defense response to virus [GO:0051607]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of JNK cascade [GO:0046330]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of cytokine production [GO:0001817]; regulation of defense response to virus [GO:0050688]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of interferon-beta production [GO:0032648]; regulation of proteolysis [GO:0030162]; signal transduction [GO:0007165]; Toll signaling pathway [GO:0008063]; toll-like receptor signaling pathway [GO:0002224]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; type I interferon-mediated signaling pathway [GO:0060337] GO:0000151; GO:0001817; GO:0002224; GO:0004842; GO:0005164; GO:0005739; GO:0005768; GO:0005829; GO:0006915; GO:0007165; GO:0008063; GO:0008270; GO:0009898; GO:0019901; GO:0019903; GO:0030162; GO:0031625; GO:0031996; GO:0032088; GO:0032648; GO:0033209; GO:0035631; GO:0035666; GO:0042802; GO:0042981; GO:0043122; GO:0046330; GO:0050688; GO:0051607; GO:0060337; GO:0070534; GO:1902554 28291 XM_044321402.1 382 274 115 402 252 A9JS51 1.42e-55 Protein FAM166B Xenopus laevis (African clawed frog) NA GO:0005879 28292 XM_029338737.2 0 26 26 115 0 Q9BVH7 5.76e-24 Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 (EC 2.4.99.-) (GD1 alpha synthase) (GalNAc alpha-2,6-sialyltransferase V) (ST6GalNAc V) (ST6GalNAcV) (Sialyltransferase 7E) (SIAT7-E) Homo sapiens (Human) ganglioside biosynthetic process [GO:0001574]; glycosphingolipid biosynthetic process [GO:0006688]; oligosaccharide biosynthetic process [GO:0009312]; oligosaccharide metabolic process [GO:0009311]; protein glycosylation [GO:0006486] GO:0000139; GO:0001574; GO:0001665; GO:0006486; GO:0006688; GO:0008373; GO:0009311; GO:0009312 28293 XM_029335404.2 4102 3360 2127 2541 2243 P61917 4.03e-37 NPC intracellular cholesterol transporter 2 (EPI-1) (Epididymal secretory protein E1) (Niemann Pick type C2 protein homolog) Pan troglodytes (Chimpanzee) cholesterol efflux [GO:0033344]; cholesterol metabolic process [GO:0008203]; cholesterol transport [GO:0030301]; intracellular cholesterol transport [GO:0032367]; sterol transport [GO:0015918] GO:0005615; GO:0005764; GO:0005783; GO:0008203; GO:0015485; GO:0015918; GO:0030301; GO:0032367; GO:0032934; GO:0033344 28294 XR_006391705.1 170 212 0 328 13 NA NA NA NA NA NA 28295 XM_029345673.2 0 0 103 107 0 Q8K0Q5 3.01e-95 Rho GTPase-activating protein 18 (Rho-type GTPase-activating protein 18) Mus musculus (Mouse) regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin filament polymerization [GO:0030833]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of small GTPase mediated signal transduction [GO:0051056]; small GTPase mediated signal transduction [GO:0007264] GO:0001726; GO:0005096; GO:0005737; GO:0005829; GO:0005881; GO:0005886; GO:0007264; GO:0008360; GO:0016607; GO:0030833; GO:0032956; GO:0051056; GO:2000145 28296 XM_044308458.1 5 558 146 224 151 P00521 5.22e-25 Tyrosine-protein kinase transforming protein Abl (EC 2.7.10.2) (V-abl) Abelson murine leukemia virus NA GO:0004715; GO:0005524 28297 XM_029333025.2 16 15 19 88 25 Q811I0 3.71e-48 ATP synthase mitochondrial F1 complex assembly factor 1 Mus musculus (Mouse) mitochondrial proton-transporting ATP synthase complex assembly [GO:0033615] GO:0005739; GO:0033615 28298 XM_029352383.2 607 211 339 748 544 NA NA NA NA NA NA 28299 XR_006393249.1 6 0 13 11 37 NA NA NA NA NA NA 28300 XM_029327870.2 156 192 204 0 222 NA NA NA NA NA NA 28301 XM_029354794.2 65 103 35 64 160 NA NA NA NA NA NA 28302 XM_044311762.1 1 1 29 3 100 NA NA NA NA NA NA 28303 XM_044316241.1 615 564 289 779 752 Q8BHG1 0 Nardilysin (EC 3.4.24.61) (N-arginine dibasic convertase) (NRD convertase) (NRD-C) (Nardilysin convertase) Mus musculus (Mouse) negative regulation of cold-induced thermogenesis [GO:0120163]; positive regulation of axonogenesis [GO:0050772]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of myelination [GO:0031643]; proteolysis [GO:0006508]; regulation of endopeptidase activity [GO:0052548] GO:0004222; GO:0005739; GO:0006508; GO:0008233; GO:0030425; GO:0031643; GO:0046872; GO:0050772; GO:0051044; GO:0052548; GO:0120163 28304 XM_029339099.2 457 263 237 480 510 Q6PR54 1.28e-164 Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1) Mus musculus (Mouse) cell cycle [GO:0007049]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to leukemia inhibitory factor [GO:1990830]; DNA repair [GO:0006281]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; positive regulation of histone H3-K9 methylation [GO:0051574]; positive regulation of isotype switching [GO:0045830]; somatic stem cell population maintenance [GO:0035019]; subtelomeric heterochromatin formation [GO:0031509]; telomere maintenance [GO:0000723]; telomere maintenance in response to DNA damage [GO:0043247] GO:0000122; GO:0000723; GO:0000781; GO:0000785; GO:0000793; GO:0001939; GO:0001940; GO:0005634; GO:0005654; GO:0005737; GO:0005886; GO:0006281; GO:0006974; GO:0007049; GO:0016604; GO:0031509; GO:0031965; GO:0035019; GO:0035861; GO:0043247; GO:0045814; GO:0045830; GO:0051233; GO:0051574; GO:0140445; GO:1990830; GO:2000042; GO:2001034 28305 XM_029339099.2 457 263 237 480 510 Q6PR54 1.51e-21 Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1) Mus musculus (Mouse) cell cycle [GO:0007049]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to leukemia inhibitory factor [GO:1990830]; DNA repair [GO:0006281]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; positive regulation of histone H3-K9 methylation [GO:0051574]; positive regulation of isotype switching [GO:0045830]; somatic stem cell population maintenance [GO:0035019]; subtelomeric heterochromatin formation [GO:0031509]; telomere maintenance [GO:0000723]; telomere maintenance in response to DNA damage [GO:0043247] GO:0000122; GO:0000723; GO:0000781; GO:0000785; GO:0000793; GO:0001939; GO:0001940; GO:0005634; GO:0005654; GO:0005737; GO:0005886; GO:0006281; GO:0006974; GO:0007049; GO:0016604; GO:0031509; GO:0031965; GO:0035019; GO:0035861; GO:0043247; GO:0045814; GO:0045830; GO:0051233; GO:0051574; GO:0140445; GO:1990830; GO:2000042; GO:2001034 28306 XM_044307215.1 19397 19268 5479 16654 1594 NA NA NA NA NA NA 28307 XM_029347814.2 28650 17807 22521 16767 13677 Q92597 1.35e-45 Protein NDRG1 (Differentiation-related gene 1 protein) (DRG-1) (N-myc downstream-regulated gene 1 protein) (Nickel-specific induction protein Cap43) (Reducing agents and tunicamycin-responsive protein) (RTP) (Rit42) Homo sapiens (Human) cellular response to hypoxia [GO:0071456]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; mast cell activation [GO:0045576]; negative regulation of cell population proliferation [GO:0008285]; peripheral nervous system myelin maintenance [GO:0032287]; response to metal ion [GO:0010038]; signal transduction [GO:0007165] GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0005874; GO:0005886; GO:0005912; GO:0007165; GO:0008017; GO:0008285; GO:0010038; GO:0015630; GO:0030330; GO:0031267; GO:0032287; GO:0043015; GO:0045296; GO:0045576; GO:0048471; GO:0055038; GO:0070062; GO:0071456 28308 XM_029349811.2 1659 1108 789 1482 1342 Q9ESJ4 9.88e-83 NCK-interacting protein with SH3 domain (54 kDa VacA-interacting protein) (VIP54) (90 kDa N-WASP-interacting protein) (90 kDa SH3 protein interacting with Nck) (SH3 adapter protein SPIN90) (WASP-interacting SH3-domain protein) (WISH) (Wiskott-Aldrich syndrome protein-binding protein) (N-WASP-binding protein) Mus musculus (Mouse) endocytosis [GO:0006897]; positive regulation of neuron projection development [GO:0010976] GO:0006897; GO:0008180; GO:0010976; GO:0017124; GO:0071933 28309 XM_044311222.1 20 7 39 20 193 P46023 4.19e-92 G-protein coupled receptor GRL101 Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004930; GO:0005886 28310 XM_029325709.2 1 14 9 0 11 NA NA NA NA NA NA 28311 XR_006395750.1 113 152 97 121 131 NA NA NA NA NA NA 28312 XM_029338171.2 1900 1846 1151 2110 2220 NA NA NA NA NA NA 28313 XM_044324952.1 0 572 698 61 292 NA NA NA NA NA NA 28314 XM_044316148.1 11 6 9 21 30 NA NA NA NA NA NA 28315 XM_044322994.1 342 41 53 202 393 NA NA NA NA NA NA 28316 XM_044313386.1 44 29 67 56 170 NA NA NA NA NA NA 28317 XM_044324987.1 49 55 27 23 204 Q9TV36 1.12e-28 Fibrillin-1 [Cleaved into: Asprosin] Sus scrofa (Pig) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 28318 XM_044324987.1 49 55 27 23 204 Q9TV36 4.05e-24 Fibrillin-1 [Cleaved into: Asprosin] Sus scrofa (Pig) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 28319 XM_044324987.1 49 55 27 23 204 Q9TV36 4.07e-23 Fibrillin-1 [Cleaved into: Asprosin] Sus scrofa (Pig) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 28320 XM_044324987.1 49 55 27 23 204 Q9TV36 9.58e-21 Fibrillin-1 [Cleaved into: Asprosin] Sus scrofa (Pig) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 28321 XR_006392142.1 9 0 0 2 2 NA NA NA NA NA NA 28322 XM_029350218.2 742 743 520 564 571 Q9H0R3 1.59e-79 Transmembrane protein 222 Homo sapiens (Human) NA GO:0016020; GO:0030425 28323 XM_029346877.2 13 14 9 0 14 NA NA NA NA NA NA 28324 XM_029358341.2 1 6 11 6 0 NA NA NA NA NA NA 28325 XM_029329799.2 312 109 4 0 117 Q6AYM1 5.62e-30 Uncharacterized protein C5orf34 homolog Rattus norvegicus (Rat) NA NA 28326 XM_029325176.2 3344 1778 1483 2598 2125 NA NA NA NA NA NA 28327 XM_029323504.2 89 81 56 77 146 Q3KRG3 3.68e-23 Pre-rRNA-processing protein TSR2 homolog Danio rerio (Zebrafish) (Brachydanio rerio) maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462] GO:0000462; GO:0005634 28328 XM_029346321.2 0 0 44 0 0 O00305 2.4e-63 Voltage-dependent L-type calcium channel subunit beta-4 (CAB4) (Calcium channel voltage-dependent subunit beta 4) Homo sapiens (Human) adult walking behavior [GO:0007628]; cAMP metabolic process [GO:0046058]; cellular response to leukemia inhibitory factor [GO:1990830]; chemical synaptic transmission [GO:0007268]; detection of light stimulus involved in visual perception [GO:0050908]; gamma-aminobutyric acid secretion [GO:0014051]; gamma-aminobutyric acid signaling pathway [GO:0007214]; muscle cell development [GO:0055001]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; neuromuscular junction development [GO:0007528]; neuronal action potential propagation [GO:0019227]; Peyer's patch development [GO:0048541]; positive regulation of protein localization to nucleolus [GO:1904751]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; regulation of synaptic vesicle exocytosis [GO:2000300]; regulation of voltage-gated calcium channel activity [GO:1901385]; spleen development [GO:0048536]; synaptic transmission, glutamatergic [GO:0035249]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538] GO:0005730; GO:0005829; GO:0005886; GO:0005891; GO:0007214; GO:0007268; GO:0007528; GO:0007628; GO:0008285; GO:0009898; GO:0014051; GO:0016607; GO:0019227; GO:0019901; GO:0035249; GO:0045202; GO:0046058; GO:0048536; GO:0048538; GO:0048541; GO:0050852; GO:0050908; GO:0055001; GO:0098793; GO:0098978; GO:0099626; GO:1901385; GO:1901387; GO:1904751; GO:1990830; GO:2000134; GO:2000300 28329 XM_029354877.2 50 697 31 64 89 NA NA NA NA NA NA 28330 XR_006397920.1 0 19 0 0 18 NA NA NA NA NA NA 28331 XR_006392689.1 0 0 0 0 42 NA NA NA NA NA NA 28332 XM_029351363.2 15 21 0 0 137 Q19749 8.15e-164 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial (EC 2.3.1.12) (Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex) (Pyruvate dehydrogenase complex component E2) (PDC-E2) (PDCE2) Caenorhabditis elegans acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glycolytic process [GO:0006096] GO:0004742; GO:0005967; GO:0006086; GO:0006096 28333 XM_044312755.1 18 2 0 0 0 P35061 1.24e-64 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 28334 XM_044311306.1 126 100 19 73 141 Q91W78 3.46e-41 U6 snRNA phosphodiesterase 1 (3'-5' RNA exonuclease USB1) (EC 4.6.1.-) Mus musculus (Mouse) RNA splicing [GO:0008380]; snRNA 3'-end processing [GO:0034472]; U6 snRNA 3'-end processing [GO:0034477] GO:0000175; GO:0005634; GO:0005654; GO:0008380; GO:0016829; GO:0034472; GO:0034477; GO:0045171; GO:1990838 28335 XM_029333751.2 4102 4313 2617 3914 3851 Q3B8Q2 0 Eukaryotic initiation factor 4A-III (eIF-4A-III) (eIF4A-III) (EC 3.6.4.13) (ATP-dependent RNA helicase DDX48) (ATP-dependent RNA helicase eIF4A-3) (DEAD box protein 48) (Eukaryotic translation initiation factor 4A isoform 3) [Cleaved into: Eukaryotic initiation factor 4A-III, N-terminally processed] Rattus norvegicus (Rat) associative learning [GO:0008306]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to selenite ion [GO:0072715]; embryonic cranial skeleton morphogenesis [GO:0048701]; exploration behavior [GO:0035640]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of gene expression [GO:0010629]; negative regulation of selenocysteine incorporation [GO:1904570]; negative regulation of selenocysteine insertion sequence binding [GO:1904574]; negative regulation of translation [GO:0017148]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translation [GO:0045727]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of mRNA binding [GO:1902415]; regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000622]; regulation of translation at postsynapse, modulating synaptic transmission [GO:0099578]; response to organic cyclic compound [GO:0014070]; rRNA processing [GO:0006364] GO:0000184; GO:0000381; GO:0000398; GO:0003723; GO:0003724; GO:0003729; GO:0005524; GO:0005634; GO:0005730; GO:0005737; GO:0006364; GO:0008143; GO:0008306; GO:0010629; GO:0014070; GO:0016607; GO:0016887; GO:0017148; GO:0030425; GO:0035145; GO:0035368; GO:0035613; GO:0035640; GO:0043021; GO:0043025; GO:0045182; GO:0045727; GO:0045944; GO:0048026; GO:0048701; GO:0051028; GO:0071006; GO:0071013; GO:0072715; GO:0090394; GO:0098794; GO:0098978; GO:0099578; GO:1902415; GO:1904570; GO:1904574; GO:1990416; GO:1990904; GO:2000622 28336 XR_006393585.1 649 522 419 694 746 NA NA NA NA NA NA 28337 XM_044326191.1 0 12 6 1 60 NA NA NA NA NA NA 28338 XM_029339517.2 31 47 0 42 25 A7RWP6 4.13e-51 Eukaryotic translation initiation factor 3 subunit E (eIF3e) (Eukaryotic translation initiation factor 3 subunit 6) Nematostella vectensis (Starlet sea anemone) formation of cytoplasmic translation initiation complex [GO:0001732]; translational initiation [GO:0006413] GO:0001732; GO:0003743; GO:0005634; GO:0005852; GO:0006413; GO:0016282; GO:0033290; GO:0071540 28339 XM_029328999.2 291 41 0 115 146 Q8N543 3.84e-125 Prolyl 3-hydroxylase OGFOD1 (EC 1.14.11.-) (2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1) (Termination and polyadenylation 1 homolog) (uS12 prolyl 3-hydroxylase) Homo sapiens (Human) cell population proliferation [GO:0008283]; peptidyl-proline hydroxylation [GO:0019511]; protein hydroxylation [GO:0018126]; regulation of translational termination [GO:0006449]; stress granule assembly [GO:0034063] GO:0005506; GO:0005654; GO:0005737; GO:0005829; GO:0006449; GO:0008283; GO:0010494; GO:0018126; GO:0019511; GO:0031418; GO:0031543; GO:0031544; GO:0034063 28340 XM_044316985.1 95 37 85 59 44 NA NA NA NA NA NA 28341 XM_044328761.1 45 0 0 127 42 NA NA NA NA NA NA 28342 XM_029339848.2 784 588 678 659 641 Q6IRP4 1.75e-99 Protein ABHD13 (EC 3.-.-.-) (Alpha/beta hydrolase domain-containing protein 13) (Abhydrolase domain-containing protein 13) Xenopus laevis (African clawed frog) NA GO:0016020; GO:0016787 28343 XR_003824793.2 155 12 4 46 48 NA NA NA NA NA NA 28344 XM_029335575.2 0 126 9 23 134 Q6DJH2 5.4e-77 L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase (EC 2.7.8.7) (4'-phosphopantetheinyl transferase) (Alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase) (AASD-PPT) Xenopus laevis (African clawed frog) fatty acid biosynthetic process [GO:0006633]; protein maturation [GO:0051604] GO:0000287; GO:0005829; GO:0006633; GO:0008897; GO:0051604 28345 XM_044308024.1 402 364 233 274 527 P98156 1.58e-155 Very low-density lipoprotein receptor (VLDL receptor) (VLDL-R) Mus musculus (Mouse) cellular response to hypoxia [GO:0071456]; cholesterol metabolic process [GO:0008203]; dendrite morphogenesis [GO:0048813]; glycoprotein transport [GO:0034436]; lipid transport [GO:0006869]; positive regulation of dendrite development [GO:1900006]; positive regulation of protein kinase activity [GO:0045860]; receptor-mediated endocytosis [GO:0006898]; reelin-mediated signaling pathway [GO:0038026]; ventral spinal cord development [GO:0021517]; very-low-density lipoprotein particle clearance [GO:0034447] GO:0005509; GO:0005615; GO:0005634; GO:0005886; GO:0005905; GO:0006869; GO:0006898; GO:0008203; GO:0009986; GO:0016020; GO:0021517; GO:0030229; GO:0034185; GO:0034189; GO:0034361; GO:0034436; GO:0034447; GO:0038024; GO:0038025; GO:0038026; GO:0043235; GO:0045177; GO:0045860; GO:0048306; GO:0048471; GO:0048813; GO:0071456; GO:1900006 28346 XM_029348549.2 261 85 83 175 277 NA NA NA NA NA NA 28347 XR_006396542.1 0 24 0 43 0 NA NA NA NA NA NA 28348 XM_044312595.1 16118 9278 5831 15348 16854 NA NA NA NA NA NA 28349 XM_029345110.2 22 22 42 32 42 Q9DBW0 5.7e-156 Cytochrome P450 4V2 (Docosahexaenoic acid omega-hydroxylase CYP4V2) (EC 1.14.14.79) (Long-chain fatty acid omega-monooxygenase) (EC 1.14.14.80) Mus musculus (Mouse) fatty acid omega-oxidation [GO:0010430] GO:0005506; GO:0005789; GO:0010430; GO:0020037; GO:0102033 28350 XM_044327154.1 68 61 39 123 166 B8VIW9 0 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 28351 XM_044327154.1 68 61 39 123 166 B8VIW9 4.55e-50 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 28352 XM_044319408.1 985 454 305 737 710 Q60997 1.39e-36 Deleted in malignant brain tumors 1 protein (Apactin) (CRP-ductin) (Glycoprotein 300) (gp300) (Hensin) (Mucin-like glycoprotein) (Muclin) (Vomeroglandin) (p80) Mus musculus (Mouse) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blastocyst development [GO:0001824]; columnar/cuboidal epithelial cell differentiation [GO:0002065]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterial lipoprotein [GO:0042494]; induction of bacterial agglutination [GO:0043152]; inner cell mass cell proliferation [GO:0001833]; positive regulation of epithelial cell differentiation [GO:0030858]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617] GO:0001530; GO:0001824; GO:0001833; GO:0002065; GO:0003677; GO:0005044; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0009617; GO:0015031; GO:0019898; GO:0030658; GO:0030670; GO:0030858; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0050829; GO:0050830; GO:0050840; GO:0061844; GO:0062023; GO:0070891; GO:1904399 28353 XM_044319408.1 985 454 305 737 710 Q60997 3.19e-26 Deleted in malignant brain tumors 1 protein (Apactin) (CRP-ductin) (Glycoprotein 300) (gp300) (Hensin) (Mucin-like glycoprotein) (Muclin) (Vomeroglandin) (p80) Mus musculus (Mouse) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blastocyst development [GO:0001824]; columnar/cuboidal epithelial cell differentiation [GO:0002065]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterial lipoprotein [GO:0042494]; induction of bacterial agglutination [GO:0043152]; inner cell mass cell proliferation [GO:0001833]; positive regulation of epithelial cell differentiation [GO:0030858]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617] GO:0001530; GO:0001824; GO:0001833; GO:0002065; GO:0003677; GO:0005044; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0009617; GO:0015031; GO:0019898; GO:0030658; GO:0030670; GO:0030858; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0050829; GO:0050830; GO:0050840; GO:0061844; GO:0062023; GO:0070891; GO:1904399 28354 XM_044319408.1 985 454 305 737 710 Q60997 3.59e-26 Deleted in malignant brain tumors 1 protein (Apactin) (CRP-ductin) (Glycoprotein 300) (gp300) (Hensin) (Mucin-like glycoprotein) (Muclin) (Vomeroglandin) (p80) Mus musculus (Mouse) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blastocyst development [GO:0001824]; columnar/cuboidal epithelial cell differentiation [GO:0002065]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterial lipoprotein [GO:0042494]; induction of bacterial agglutination [GO:0043152]; inner cell mass cell proliferation [GO:0001833]; positive regulation of epithelial cell differentiation [GO:0030858]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617] GO:0001530; GO:0001824; GO:0001833; GO:0002065; GO:0003677; GO:0005044; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0009617; GO:0015031; GO:0019898; GO:0030658; GO:0030670; GO:0030858; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0050829; GO:0050830; GO:0050840; GO:0061844; GO:0062023; GO:0070891; GO:1904399 28355 XM_044319408.1 985 454 305 737 710 Q60997 3.59e-26 Deleted in malignant brain tumors 1 protein (Apactin) (CRP-ductin) (Glycoprotein 300) (gp300) (Hensin) (Mucin-like glycoprotein) (Muclin) (Vomeroglandin) (p80) Mus musculus (Mouse) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blastocyst development [GO:0001824]; columnar/cuboidal epithelial cell differentiation [GO:0002065]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterial lipoprotein [GO:0042494]; induction of bacterial agglutination [GO:0043152]; inner cell mass cell proliferation [GO:0001833]; positive regulation of epithelial cell differentiation [GO:0030858]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617] GO:0001530; GO:0001824; GO:0001833; GO:0002065; GO:0003677; GO:0005044; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0009617; GO:0015031; GO:0019898; GO:0030658; GO:0030670; GO:0030858; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0050829; GO:0050830; GO:0050840; GO:0061844; GO:0062023; GO:0070891; GO:1904399 28356 XM_044319408.1 985 454 305 737 710 Q60997 1.66e-25 Deleted in malignant brain tumors 1 protein (Apactin) (CRP-ductin) (Glycoprotein 300) (gp300) (Hensin) (Mucin-like glycoprotein) (Muclin) (Vomeroglandin) (p80) Mus musculus (Mouse) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blastocyst development [GO:0001824]; columnar/cuboidal epithelial cell differentiation [GO:0002065]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterial lipoprotein [GO:0042494]; induction of bacterial agglutination [GO:0043152]; inner cell mass cell proliferation [GO:0001833]; positive regulation of epithelial cell differentiation [GO:0030858]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617] GO:0001530; GO:0001824; GO:0001833; GO:0002065; GO:0003677; GO:0005044; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0009617; GO:0015031; GO:0019898; GO:0030658; GO:0030670; GO:0030858; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0050829; GO:0050830; GO:0050840; GO:0061844; GO:0062023; GO:0070891; GO:1904399 28357 XM_044319408.1 985 454 305 737 710 Q60997 2.29e-25 Deleted in malignant brain tumors 1 protein (Apactin) (CRP-ductin) (Glycoprotein 300) (gp300) (Hensin) (Mucin-like glycoprotein) (Muclin) (Vomeroglandin) (p80) Mus musculus (Mouse) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blastocyst development [GO:0001824]; columnar/cuboidal epithelial cell differentiation [GO:0002065]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterial lipoprotein [GO:0042494]; induction of bacterial agglutination [GO:0043152]; inner cell mass cell proliferation [GO:0001833]; positive regulation of epithelial cell differentiation [GO:0030858]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617] GO:0001530; GO:0001824; GO:0001833; GO:0002065; GO:0003677; GO:0005044; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0009617; GO:0015031; GO:0019898; GO:0030658; GO:0030670; GO:0030858; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0050829; GO:0050830; GO:0050840; GO:0061844; GO:0062023; GO:0070891; GO:1904399 28358 XM_044319408.1 985 454 305 737 710 Q60997 5.63e-25 Deleted in malignant brain tumors 1 protein (Apactin) (CRP-ductin) (Glycoprotein 300) (gp300) (Hensin) (Mucin-like glycoprotein) (Muclin) (Vomeroglandin) (p80) Mus musculus (Mouse) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blastocyst development [GO:0001824]; columnar/cuboidal epithelial cell differentiation [GO:0002065]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterial lipoprotein [GO:0042494]; induction of bacterial agglutination [GO:0043152]; inner cell mass cell proliferation [GO:0001833]; positive regulation of epithelial cell differentiation [GO:0030858]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617] GO:0001530; GO:0001824; GO:0001833; GO:0002065; GO:0003677; GO:0005044; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0009617; GO:0015031; GO:0019898; GO:0030658; GO:0030670; GO:0030858; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0050829; GO:0050830; GO:0050840; GO:0061844; GO:0062023; GO:0070891; GO:1904399 28359 XM_044319408.1 985 454 305 737 710 Q60997 3.05e-24 Deleted in malignant brain tumors 1 protein (Apactin) (CRP-ductin) (Glycoprotein 300) (gp300) (Hensin) (Mucin-like glycoprotein) (Muclin) (Vomeroglandin) (p80) Mus musculus (Mouse) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blastocyst development [GO:0001824]; columnar/cuboidal epithelial cell differentiation [GO:0002065]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterial lipoprotein [GO:0042494]; induction of bacterial agglutination [GO:0043152]; inner cell mass cell proliferation [GO:0001833]; positive regulation of epithelial cell differentiation [GO:0030858]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617] GO:0001530; GO:0001824; GO:0001833; GO:0002065; GO:0003677; GO:0005044; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0009617; GO:0015031; GO:0019898; GO:0030658; GO:0030670; GO:0030858; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0050829; GO:0050830; GO:0050840; GO:0061844; GO:0062023; GO:0070891; GO:1904399 28360 XM_044319185.1 18 9 10 9 9 Q9JMI9 4.97e-90 Short transient receptor potential channel 3 (TrpC3) (Trp-related protein 3) Rattus norvegicus (Rat) calcium ion transmembrane transport [GO:0070588]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of cardiac muscle hypertrophy in response to stress [GO:1903244]; regulation of cytosolic calcium ion concentration [GO:0051480]; response to ATP [GO:0033198]; response to calcium ion [GO:0051592]; single fertilization [GO:0007338] GO:0005227; GO:0005886; GO:0007338; GO:0010524; GO:0015279; GO:0033198; GO:0034703; GO:0046872; GO:0051480; GO:0051592; GO:0070588; GO:0070679; GO:1903244 28361 XR_006396124.1 0 33 28 100 67 NA NA NA NA NA NA 28362 XM_044322874.1 2915 1593 1610 3743 2834 Q99996 5.46e-37 A-kinase anchor protein 9 (AKAP-9) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (A-kinase anchor protein 450 kDa) (AKAP 450) (AKAP 120-like protein) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP) (Protein hyperion) (Protein kinase A-anchoring protein 9) (PRKA9) (Protein yotiao) Homo sapiens (Human) cellular response to cAMP [GO:0071320]; chemical synaptic transmission [GO:0007268]; maintenance of centrosome location [GO:0051661]; microtubule nucleation [GO:0007020]; negative regulation of adenylate cyclase activity [GO:0007194]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; protein-containing complex localization [GO:0031503]; regulation of cardiac muscle cell action potential involved in regulation of contraction [GO:0098909]; regulation of Golgi organization [GO:1903358]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of membrane repolarization [GO:0060306]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; response to electrical stimulus [GO:0051602]; signal transduction [GO:0007165] GO:0003677; GO:0005102; GO:0005794; GO:0005795; GO:0005801; GO:0005813; GO:0005829; GO:0005856; GO:0007020; GO:0007165; GO:0007194; GO:0007268; GO:0008076; GO:0015459; GO:0031116; GO:0031503; GO:0033138; GO:0034237; GO:0034705; GO:0043025; GO:0043231; GO:0044307; GO:0044325; GO:0051602; GO:0051661; GO:0060090; GO:0060306; GO:0060307; GO:0071320; GO:0086091; GO:0097060; GO:0098909; GO:0098962; GO:0098978; GO:0099147; GO:1901018; GO:1903358 28363 XM_029324884.2 227 0 0 0 69 Q9HF54 2.16e-40 GTP-binding protein RHO1 Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii) actin filament organization [GO:0007015]; cortical cytoskeleton organization [GO:0030865]; establishment or maintenance of cell polarity [GO:0007163]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; small GTPase mediated signal transduction [GO:0007264] GO:0003924; GO:0005525; GO:0005856; GO:0005886; GO:0005938; GO:0007015; GO:0007163; GO:0007264; GO:0008360; GO:0019901; GO:0030865; GO:0031410; GO:0032956; GO:0042995 28364 XM_044312089.1 25 435 109 0 68 Q99MW1 4.71e-30 Serine/threonine-protein kinase 31 (EC 2.7.11.1) Mus musculus (Mouse) protein phosphorylation [GO:0006468] GO:0001669; GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0006468; GO:0106310 28365 XM_044314521.1 89 33 94 59 190 NA NA NA NA NA NA 28366 XR_006396541.1 422 243 459 527 807 NA NA NA NA NA NA 28367 XM_044318800.1 121 42 30 109 18 P07550 5.66e-25 Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor) Homo sapiens (Human) activation of adenylate cyclase activity [GO:0007190]; activation of transmembrane receptor protein tyrosine kinase activity [GO:0007171]; adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; adrenergic receptor signaling pathway [GO:0071875]; bone resorption [GO:0045453]; brown fat cell differentiation [GO:0050873]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amyloid-beta [GO:1904646]; desensitization of G protein-coupled receptor signaling pathway by arrestin [GO:0002032]; diet induced thermogenesis [GO:0002024]; endosome to lysosome transport [GO:0008333]; heat generation [GO:0031649]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of smooth muscle contraction [GO:0045986]; norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0002025]; positive regulation of AMPA receptor activity [GO:2000969]; positive regulation of autophagosome maturation [GO:1901098]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cAMP-dependent protein kinase activity [GO:2000481]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of lipophagy [GO:1904504]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mini excitatory postsynaptic potential [GO:0061885]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor-mediated endocytosis [GO:0006898]; regulation of sodium ion transport [GO:0002028]; response to cold [GO:0009409]; response to psychosocial stress [GO:1990911]; smooth muscle contraction [GO:0006939]; transcription by RNA polymerase II [GO:0006366] GO:0001540; GO:0002024; GO:0002025; GO:0002028; GO:0002032; GO:0004930; GO:0004941; GO:0005634; GO:0005764; GO:0005768; GO:0005769; GO:0005794; GO:0005886; GO:0006366; GO:0006898; GO:0006939; GO:0007166; GO:0007171; GO:0007188; GO:0007190; GO:0008179; GO:0008333; GO:0009409; GO:0010008; GO:0010739; GO:0015459; GO:0016020; GO:0016324; GO:0030501; GO:0030669; GO:0031649; GO:0040015; GO:0042802; GO:0042803; GO:0043235; GO:0043410; GO:0044877; GO:0045453; GO:0045944; GO:0045986; GO:0050873; GO:0051380; GO:0061885; GO:0071875; GO:0071880; GO:0071902; GO:0098992; GO:0120162; GO:1901098; GO:1904504; GO:1904646; GO:1990911; GO:2000481; GO:2000969 28368 XM_044324221.1 0 6 0 0 0 NA NA NA NA NA NA 28369 XM_044323114.1 160 44 87 103 254 NA NA NA NA NA NA 28370 XM_044307537.1 165 170 251 827 453 Q6UWX4 2.1e-166 HHIP-like protein 2 Homo sapiens (Human) NA GO:0005576 28371 XM_044324698.1 739 743 460 541 570 NA NA NA NA NA NA 28372 XM_029351897.2 6 26 17 22 42 NA NA NA NA NA NA 28373 XM_044329067.1 10 16 0 12 38 NA NA NA NA NA NA 28374 XM_044309383.1 12 5 7 0 2 NA NA NA NA NA NA 28375 XM_029355504.2 21 16 1 18 6 Q9EQM3 5.73e-23 Homeobox protein Nkx-2.4 (Homeobox protein NK-2 homolog D) Mus musculus (Mouse) cell differentiation [GO:0030154]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0030154 28376 XM_029350622.2 49907 45579 20721 46432 21845 Q13887 9.57e-25 Krueppel-like factor 5 (Basic transcription element-binding protein 2) (BTE-binding protein 2) (Colon krueppel-like factor) (GC-box-binding protein 2) (Intestinal-enriched krueppel-like factor) (Transcription factor BTEB2) Homo sapiens (Human) angiogenesis [GO:0001525]; cell-cell signaling via exosome [GO:0099156]; cellular response to leukemia inhibitory factor [GO:1990830]; intestinal epithelial cell development [GO:0060576]; microvillus assembly [GO:0030033]; myotube differentiation involved in skeletal muscle regeneration [GO:0014908]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription by transcription factor localization [GO:0061586]; regulation of microvillus assembly [GO:0032534]; regulation of transcription by RNA polymerase II [GO:0006357]; satellite cell activation involved in skeletal muscle regeneration [GO:0014901]; skeletal muscle satellite cell differentiation [GO:0014816] GO:0000122; GO:0000785; GO:0000978; GO:0000981; GO:0001228; GO:0001525; GO:0005654; GO:0005667; GO:0005794; GO:0006357; GO:0014816; GO:0014901; GO:0014908; GO:0030033; GO:0032534; GO:0043231; GO:0043426; GO:0045600; GO:0045944; GO:0046872; GO:0060576; GO:0061586; GO:0099156; GO:1902895; GO:1990830; GO:1990837 28377 XR_006397752.1 183 52 39 51 22 NA NA NA NA NA NA 28378 XM_029324366.2 39 9 56 124 71 NA NA NA NA NA NA 28379 XR_006396366.1 1327 1174 801 1250 836 NA NA NA NA NA NA 28380 XM_044313060.1 48 10 19 39 2 NA NA NA NA NA NA 28381 XM_044322834.1 70 0 0 1 16 Q5DU56 1.58e-25 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 28382 XM_044322834.1 70 0 0 1 16 Q5DU56 4.1e-22 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 28383 XM_044320841.1 44 71 67 28 50 Q8K3Z0 1.04e-32 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 28384 XM_044322871.1 150 129 47 279 261 E7F9T0 1.12e-171 [F-actin]-monooxygenase mical1 (EC 1.14.13.225) (EC 1.6.3.1) (Molecule interacting with CasL protein 1) (MICAL-1) Danio rerio (Zebrafish) (Brachydanio rerio) actin filament depolymerization [GO:0030042]; animal organ development [GO:0048513]; sulfur oxidation [GO:0019417] GO:0003779; GO:0005737; GO:0005856; GO:0016709; GO:0019417; GO:0030042; GO:0046872; GO:0048513; GO:0071949; GO:0106294 28385 XM_044313866.1 302 645 1070 1267 1042 NA NA NA NA NA NA 28386 XR_006396076.1 1 3 21 1 90 P04323 1.08e-32 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 28387 XM_044326929.1 37 15 7 21 41 NA NA NA NA NA NA 28388 XM_029352019.2 752 888 500 536 386 Q8NDA2 1.4e-32 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 28389 XM_029352019.2 752 888 500 536 386 Q8NDA2 5.03e-32 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 28390 XM_029352019.2 752 888 500 536 386 Q8NDA2 9.4e-31 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 28391 XM_029352019.2 752 888 500 536 386 Q8NDA2 2.93e-27 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 28392 XM_029352019.2 752 888 500 536 386 Q8NDA2 2.2e-26 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 28393 XM_029352019.2 752 888 500 536 386 Q8NDA2 5.82e-26 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 28394 XM_029352019.2 752 888 500 536 386 Q8NDA2 3.4e-24 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 28395 XM_029352019.2 752 888 500 536 386 Q8NDA2 5.57e-24 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 28396 XM_029352019.2 752 888 500 536 386 Q8NDA2 8.38e-24 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 28397 XM_029352019.2 752 888 500 536 386 Q8NDA2 8.71e-23 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 28398 XM_029352019.2 752 888 500 536 386 Q8NDA2 2.42e-22 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 28399 XM_029352019.2 752 888 500 536 386 Q8NDA2 1.02e-21 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 28400 XM_029352019.2 752 888 500 536 386 Q8NDA2 1.43e-21 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 28401 XM_029324785.2 2 0 0 19 14 NA NA NA NA NA NA 28402 XM_029336892.2 182 61 96 121 221 NA NA NA NA NA NA 28403 XM_029351405.2 409 95 98 99 56 NA NA NA NA NA NA 28404 XM_029331796.2 718 405 330 583 392 O02776 0 Poly(ADP-ribose) glycohydrolase (EC 3.2.1.143) Bos taurus (Bovine) ATP generation from poly-ADP-D-ribose [GO:1990966]; carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide-sugar metabolic process [GO:0009225]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056] GO:0004649; GO:0005634; GO:0005737; GO:0005975; GO:0006282; GO:0006974; GO:0009225; GO:0031056; GO:1990966 28405 XM_044317056.1 319 184 163 187 330 Q9QX47 2.64e-66 Protein SON (Negative regulatory element-binding protein) (NRE-binding protein) Mus musculus (Mouse) microtubule cytoskeleton organization [GO:0000226]; mitotic cytokinesis [GO:0000281]; mRNA processing [GO:0006397]; negative regulation of apoptotic process [GO:0043066]; regulation of cell cycle [GO:0051726]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380] GO:0000226; GO:0000281; GO:0003677; GO:0003723; GO:0006397; GO:0008380; GO:0016607; GO:0043066; GO:0043484; GO:0048024; GO:0050733; GO:0051726 28406 XM_044314155.1 5 8 0 30 5 O46374 3.29e-40 DNA topoisomerase 2-alpha (EC 5.6.2.2) (DNA topoisomerase II, alpha isozyme) Sus scrofa (Pig) apoptotic chromosome condensation [GO:0030263]; cellular response to DNA damage stimulus [GO:0006974]; DNA ligation [GO:0006266]; DNA topological change [GO:0006265]; embryonic cleavage [GO:0040016]; female meiotic nuclear division [GO:0007143]; hematopoietic progenitor cell differentiation [GO:0002244]; negative regulation of DNA duplex unwinding [GO:1905463]; positive regulation of apoptotic process [GO:0043065]; positive regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045870]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of circadian rhythm [GO:0042752]; resolution of meiotic recombination intermediates [GO:0000712]; rhythmic process [GO:0048511]; sister chromatid segregation [GO:0000819] GO:0000228; GO:0000287; GO:0000712; GO:0000775; GO:0000793; GO:0000819; GO:0001673; GO:0002244; GO:0003682; GO:0003918; GO:0005080; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005814; GO:0006265; GO:0006266; GO:0006974; GO:0007143; GO:0008022; GO:0008301; GO:0009330; GO:0030263; GO:0040016; GO:0042752; GO:0042803; GO:0042826; GO:0043065; GO:0043130; GO:0045870; GO:0045944; GO:0046982; GO:0048511; GO:1905463; GO:1990904 28407 XM_044309038.1 43 3 0 13 0 NA NA NA NA NA NA 28408 XM_029334208.2 2059 812 525 746 479 NA NA NA NA NA NA 28409 XM_044306752.1 10 0 0 0 71 NA NA NA NA NA NA 28410 XM_029356737.2 284 10 165 282 229 A0JNN3 4.99e-58 Mediator of RNA polymerase II transcription subunit 31 (Mediator complex subunit 31) (Mediator complex subunit SOH1) Bos taurus (Bovine) limb development [GO:0060173]; negative regulation of fibroblast proliferation [GO:0048147]; regulation of DNA-templated transcription [GO:0006355] GO:0003712; GO:0006355; GO:0016592; GO:0048147; GO:0060173; GO:0070847 28411 XR_006397395.1 19 22 18 15 43 NA NA NA NA NA NA 28412 XM_044324126.1 6 0 0 1 0 NA NA NA NA NA NA 28413 XM_029343198.2 1258 60 295 609 801 Q95028 3.68e-149 L-lactate dehydrogenase (EC 1.1.1.27) Drosophila melanogaster (Fruit fly) carboxylic acid metabolic process [GO:0019752] GO:0004459; GO:0005737; GO:0019752 28414 XM_044308886.1 367 546 56 9 394 NA NA NA NA NA NA 28415 XM_044325753.1 4 1 9 19 2 P48733 1.1e-26 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Bos taurus (Bovine) antibacterial innate immune response [GO:0140367]; defense response to Gram-negative bacterium [GO:0050829] GO:0000922; GO:0005201; GO:0005509; GO:0005576; GO:0005929; GO:0016020; GO:0016323; GO:0016324; GO:0031012; GO:0050829; GO:0060170; GO:0140367 28416 XM_029329610.2 202 113 125 118 235 Q6W3F4 2.83e-22 Adenosine receptor A2b Canis lupus familiaris (Dog) (Canis familiaris) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; G protein-coupled receptor signaling pathway [GO:0007186]; vasodilation [GO:0042311] GO:0001609; GO:0004930; GO:0005886; GO:0007186; GO:0007189; GO:0042311 28417 XR_006393353.1 17 19 13 13 25 NA NA NA NA NA NA 28418 XR_006396164.1 4 14 0 12 4 NA NA NA NA NA NA 28419 XM_044324510.1 33 448 50 224 271 Q7Z4T9 0 Cilia- and flagella-associated protein 91 (CFAP91) (AMY-1-associating protein expressed in testis 1) (AAT-1) (MYCBP/AMY-1-associated testis-expressed protein 1) (Protein MAATS1) Homo sapiens (Human) axonemal central apparatus assembly [GO:1904158]; cell differentiation [GO:0030154]; cilium movement [GO:0003341]; spermatogenesis [GO:0007283] GO:0003341; GO:0005739; GO:0005930; GO:0007283; GO:0030154; GO:0031514; GO:1904158 28420 XM_044326651.1 8 17 25 26 50 NA NA NA NA NA NA 28421 XM_044319491.1 1097 854 636 1017 660 Q6ZQR2 5.54e-33 Cilia- and flagella-associated protein 77 Homo sapiens (Human) NA GO:0005929 28422 XM_044321468.1 224 88 90 193 142 Q8TEA7 0 TBC domain-containing protein kinase-like protein Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; activation of GTPase activity [GO:0090630]; cell population proliferation [GO:0008283]; regulation of TOR signaling [GO:0032006] GO:0004672; GO:0005096; GO:0005524; GO:0005737; GO:0008283; GO:0030036; GO:0030496; GO:0032006; GO:0072686; GO:0090630 28423 XM_029344875.2 1205 910 647 974 1041 Q99816 6.33e-101 Tumor susceptibility gene 101 protein (ESCRT-I complex subunit TSG101) Homo sapiens (Human) autophagosome maturation [GO:0097352]; cell cycle [GO:0007049]; cell division [GO:0051301]; endosome to lysosome transport [GO:0008333]; exosomal secretion [GO:1990182]; extracellular transport [GO:0006858]; keratinocyte differentiation [GO:0030216]; macroautophagy [GO:0016236]; membrane fission [GO:0090148]; multivesicular body assembly [GO:0036258]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of ubiquitin-dependent endocytosis [GO:2000397]; positive regulation of viral budding via host ESCRT complex [GO:1903774]; protein monoubiquitination [GO:0006513]; protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]; regulation of cell cycle [GO:0051726]; regulation of cell growth [GO:0001558]; regulation of extracellular exosome assembly [GO:1903551]; regulation of MAP kinase activity [GO:0043405]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; viral budding [GO:0046755]; viral budding via host ESCRT complex [GO:0039702]; viral release from host cell [GO:0019076] GO:0000122; GO:0000813; GO:0001558; GO:0003677; GO:0003714; GO:0005730; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005771; GO:0005815; GO:0005829; GO:0005886; GO:0006513; GO:0006858; GO:0007049; GO:0007175; GO:0008285; GO:0008333; GO:0010008; GO:0016236; GO:0019076; GO:0030216; GO:0030374; GO:0031625; GO:0031901; GO:0031902; GO:0036258; GO:0039702; GO:0042059; GO:0042803; GO:0043130; GO:0043162; GO:0043328; GO:0043405; GO:0044877; GO:0046755; GO:0046790; GO:0048306; GO:0051301; GO:0051726; GO:0070062; GO:0090148; GO:0090543; GO:0097352; GO:1903543; GO:1903551; GO:1903774; GO:1990182; GO:2000397 28424 XM_029343201.2 73 32 28 13 51 NA NA NA NA NA NA 28425 XM_044327429.1 19 0 0 2 0 Q8N539 4.21e-68 Fibrinogen C domain-containing protein 1 Homo sapiens (Human) cell adhesion [GO:0007155] GO:0005102; GO:0005615; GO:0007155; GO:0008061; GO:0016020; GO:0046872; GO:0062023 28426 XM_044320614.1 106 65 64 120 112 P23780 0 Beta-galactosidase (EC 3.2.1.23) (Acid beta-galactosidase) (Lactase) Mus musculus (Mouse) cellular carbohydrate metabolic process [GO:0044262]; galactose catabolic process [GO:0019388]; response to cortisone [GO:0051413]; response to Thyroglobulin triiodothyronine [GO:1904016] GO:0004565; GO:0005615; GO:0005737; GO:0005764; GO:0005773; GO:0005794; GO:0016787; GO:0016936; GO:0019388; GO:0042803; GO:0043231; GO:0044262; GO:0051413; GO:1904016 28427 XM_044310436.1 527 142 98 391 64 NA NA NA NA NA NA 28428 XM_029334769.2 812 654 548 854 727 Q5ZJA9 2.53e-40 BLOC-1-related complex subunit 5 Gallus gallus (Chicken) lysosome localization [GO:0032418]; organelle transport along microtubule [GO:0072384]; positive regulation of anterograde synaptic vesicle transport [GO:1903744] GO:0016020; GO:0030672; GO:0032418; GO:0072384; GO:0098574; GO:0099078; GO:1903744 28429 XM_044315619.1 49 6 25 47 85 NA NA NA NA NA NA 28430 XM_029337455.2 815 621 541 1133 1444 Q4TZY1 3.62e-80 ATP-sensitive inward rectifier potassium channel 12 (Potassium channel, inwardly rectifying subfamily J member 12) Bos taurus (Bovine) potassium ion import across plasma membrane [GO:1990573]; potassium ion transport [GO:0006813]; protein homotetramerization [GO:0051289]; regulation of ion transmembrane transport [GO:0034765] GO:0005242; GO:0005886; GO:0006813; GO:0016020; GO:0034765; GO:0051289; GO:1990573 28431 XM_029325190.2 424 332 344 425 687 Q9EP82 5.9e-46 tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 (Protein Wuho homolog) (mWH) (WD repeat-containing protein 4) Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; RNA (guanine-N7)-methylation [GO:0036265]; tRNA methylation [GO:0030488]; tRNA modification [GO:0006400] GO:0005634; GO:0005654; GO:0005694; GO:0005829; GO:0006400; GO:0006974; GO:0030488; GO:0036265; GO:0043527 28432 XR_006394608.1 1 16 6 7 16 NA NA NA NA NA NA 28433 XM_044319893.1 121 143 88 92 115 Q5R8P3 1.32e-32 Bardet-Biedl syndrome 10 protein homolog Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) chaperone-mediated protein complex assembly [GO:0051131] GO:0005524; GO:0005929; GO:0051131 28434 XM_029346828.2 82 48 4 46 68 NA NA NA NA NA NA 28435 XM_044316992.1 72 66 81 281 85 NA NA NA NA NA NA 28436 XR_006393923.1 41 2 25 5 151 NA NA NA NA NA NA 28437 XM_029342197.2 281 262 357 162 868 Q5F450 0 PAN2-PAN3 deadenylation complex catalytic subunit PAN2 (EC 3.1.13.4) (Inactive ubiquitin carboxyl-terminal hydrolase 52) (PAB1P-dependent poly(A)-specific ribonuclease) (Poly(A)-nuclease deadenylation complex subunit 2) (PAN deadenylation complex subunit 2) Gallus gallus (Chicken) mRNA processing [GO:0006397]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; positive regulation of cytoplasmic mRNA processing body assembly [GO:0010606] GO:0000175; GO:0000289; GO:0000932; GO:0003676; GO:0004535; GO:0005634; GO:0006397; GO:0010606; GO:0031251; GO:0046872 28438 XR_006398136.1 0 107 16 3 27 NA NA NA NA NA NA 28439 XM_029345159.2 1023 680 626 834 766 Q9ULJ7 0 Ankyrin repeat domain-containing protein 50 Homo sapiens (Human) endocytic recycling [GO:0032456]; protein transport [GO:0015031] GO:0005768; GO:0015031; GO:0032456 28440 XM_029340134.2 575 247 377 513 599 Q8CHP0 4.47e-63 Zinc finger CCCH domain-containing protein 3 (Smad-interacting CPSF-like factor) Mus musculus (Mouse) mRNA 3'-end processing [GO:0031124]; mRNA transport [GO:0051028]; positive regulation of activin receptor signaling pathway [GO:0032927]; regulation of mRNA polyadenylation [GO:1900363] GO:0003677; GO:0005634; GO:0005847; GO:0031124; GO:0032927; GO:0046332; GO:0046872; GO:0051028; GO:0070412; GO:1900363 28441 XM_044323299.1 0 0 1 0 71 Q5R5U3 9.28e-79 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 28442 XM_044323299.1 0 0 1 0 71 Q5R5U3 1.9e-75 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 28443 XM_044323299.1 0 0 1 0 71 Q5R5U3 2e-75 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 28444 XM_044323299.1 0 0 1 0 71 Q5R5U3 4.82e-75 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 28445 XM_044323299.1 0 0 1 0 71 Q5R5U3 6e-75 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 28446 XM_044323299.1 0 0 1 0 71 Q5R5U3 9.65e-74 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 28447 XM_044323299.1 0 0 1 0 71 Q5R5U3 3.34e-73 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 28448 XM_044323299.1 0 0 1 0 71 Q5R5U3 4.19e-71 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 28449 XM_044323299.1 0 0 1 0 71 Q5R5U3 6.43e-67 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 28450 XM_044323299.1 0 0 1 0 71 Q5R5U3 1.09e-64 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 28451 XR_006396526.1 4 14 28 0 0 NA NA NA NA NA NA 28452 XM_044325749.1 0 0 15 11 0 NA NA NA NA NA NA 28453 XM_044319434.1 3 0 0 0 9 NA NA NA NA NA NA 28454 XM_044314490.1 7 0 0 0 2 NA NA NA NA NA NA 28455 XM_029348023.2 3337 2241 1587 3301 2907 NA NA NA NA NA NA 28456 XM_029355357.2 0 293 118 74 318 P78364 1.66e-38 Polyhomeotic-like protein 1 (hPH1) (Early development regulatory protein 1) Homo sapiens (Human) histone ubiquitination [GO:0016574]; negative regulation of DNA-templated transcription [GO:0045892] GO:0003677; GO:0003682; GO:0005634; GO:0005654; GO:0008270; GO:0016574; GO:0031519; GO:0035102; GO:0042393; GO:0045892 28457 XM_029351714.2 139 46 58 74 163 NA NA NA NA NA NA 28458 XM_029346135.2 529 1 36 480 696 NA NA NA NA NA NA 28459 XR_006396835.1 0 0 0 42 0 NA NA NA NA NA NA 28460 XR_006394941.1 24 15 10 0 13 NA NA NA NA NA NA 28461 XM_029345782.2 136 0 3 94 17 B8VIW9 4.52e-112 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 28462 XM_044326751.1 47 38 34 54 71 NA NA NA NA NA NA 28463 XM_044323112.1 0 0 11 0 9 P98133 1.44e-21 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 28464 XM_029335658.2 0 68 50 339 232 NA NA NA NA NA NA 28465 XM_029345264.2 370 344 126 557 382 NA NA NA NA NA NA 28466 XM_029337573.2 356 926 467 673 593 Q6GLK2 8.5e-30 Acyl-coenzyme A thioesterase THEM4 (Acyl-CoA thioesterase THEM4) (EC 3.1.2.2) (Thioesterase superfamily member 4) Xenopus laevis (African clawed frog) apoptotic process [GO:0006915]; fatty acid metabolic process [GO:0006631] GO:0005743; GO:0005758; GO:0006631; GO:0006915; GO:0016290; GO:0032587; GO:0102991 28467 XM_044313551.1 35 19 13 58 16 NA NA NA NA NA NA 28468 XM_044324242.1 3 111 28 420 47 Q6Q2B2 1.83e-63 Muscleblind-like protein 2a (Tmbnl2a) Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0003723; GO:0005634; GO:0005737; GO:0006397; GO:0008380; GO:0046872 28469 XM_044317129.1 86 0 60 137 0 NA NA NA NA NA NA 28470 XR_006397534.1 27 42 73 112 119 NA NA NA NA NA NA 28471 XM_044327342.1 262 57 32 21 49 NA NA NA NA NA NA 28472 XM_029333775.2 0 0 0 11 0 Q7TN88 3.34e-68 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 28473 XM_029333775.2 0 0 0 11 0 Q7TN88 3.25e-49 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 28474 XR_003824676.2 3732 3002 1269 3081 2354 F1RRW5 2.54e-22 Angiotensin-converting enzyme (ACE) (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) [Cleaved into: Angiotensin-converting enzyme, soluble form] Sus scrofa (Pig) amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; arachidonic acid secretion [GO:0050482]; bradykinin catabolic process [GO:0010815]; cell proliferation in bone marrow [GO:0071838]; heart contraction [GO:0060047]; hormone catabolic process [GO:0042447]; hormone metabolic process [GO:0042445]; kidney development [GO:0001822]; male gonad development [GO:0008584]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of gene expression [GO:0010629]; negative regulation of protein binding [GO:0032091]; neutrophil mediated immunity [GO:0002446]; positive regulation of peptidyl-cysteine S-nitrosylation [GO:2000170]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of protein binding [GO:0032092]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of systemic arterial blood pressure [GO:0003084]; post-transcriptional regulation of gene expression [GO:0010608]; regulation of angiotensin metabolic process [GO:0060177]; regulation of blood pressure [GO:0008217]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of synaptic plasticity [GO:0048167]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; spermatogenesis [GO:0007283]; substance P catabolic process [GO:0010814] GO:0001822; GO:0002003; GO:0002446; GO:0003081; GO:0003084; GO:0004180; GO:0004222; GO:0005516; GO:0005764; GO:0005768; GO:0005886; GO:0007283; GO:0008217; GO:0008233; GO:0008237; GO:0008240; GO:0008241; GO:0008270; GO:0008584; GO:0009897; GO:0010608; GO:0010629; GO:0010814; GO:0010815; GO:0031404; GO:0031434; GO:0031711; GO:0032091; GO:0032092; GO:0042445; GO:0042447; GO:0048167; GO:0050435; GO:0050482; GO:0051019; GO:0060047; GO:0060177; GO:0061098; GO:0070062; GO:0070573; GO:0071838; GO:1900086; GO:1902033; GO:1903597; GO:2000170 28475 XM_044323255.1 0 60 55 0 73 O73792 7.75e-53 Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1) Danio rerio (Zebrafish) (Brachydanio rerio) angiogenesis [GO:0001525]; blood vessel development [GO:0001568]; endothelial cell-cell adhesion [GO:0071603]; heart development [GO:0007507]; positive regulation of angiogenesis [GO:0045766]; positive regulation of kinase activity [GO:0033674]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculature development [GO:0001944] GO:0001525; GO:0001568; GO:0001944; GO:0004714; GO:0005524; GO:0005886; GO:0007169; GO:0007507; GO:0033674; GO:0043235; GO:0045766; GO:0071603 28476 XM_044316214.1 38 19 42 87 62 D3YXG0 4e-39 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 28477 XM_044316214.1 38 19 42 87 62 D3YXG0 4.18e-39 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 28478 XM_044316214.1 38 19 42 87 62 D3YXG0 3.05e-36 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 28479 XM_044316214.1 38 19 42 87 62 D3YXG0 1.26e-35 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 28480 XM_044316214.1 38 19 42 87 62 D3YXG0 2.16e-34 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 28481 XM_044316214.1 38 19 42 87 62 D3YXG0 4.32e-30 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 28482 XM_044316214.1 38 19 42 87 62 D3YXG0 6.95e-28 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 28483 XM_044316214.1 38 19 42 87 62 D3YXG0 5.49e-22 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 28484 XM_044315434.1 72 0 0 0 18 Q8D3M4 5.29e-79 2-aminoethylphosphonate--pyruvate transaminase (EC 2.6.1.37) (2-aminoethylphosphonate aminotransferase) (AEP transaminase) (AEPT) Vibrio vulnificus (strain CMCP6) organic phosphonate catabolic process [GO:0019700] GO:0019700; GO:0047304 28485 XM_029331932.2 274 0 234 316 610 Q58D84 2.13e-64 Follistatin-related protein 1 (Follistatin-like protein 1) Bos taurus (Bovine) cell differentiation [GO:0030154]; endothelial cell differentiation [GO:0045446]; endothelial cell migration [GO:0043542]; negative regulation of apoptotic process [GO:0043066]; regulation of BMP signaling pathway [GO:0030510] GO:0005509; GO:0005576; GO:0008201; GO:0030154; GO:0030510; GO:0043066; GO:0043542; GO:0045446 28486 XM_029340486.2 75 73 82 99 126 Q3SZE9 1.11e-60 Tubulin-specific chaperone C (Tubulin-folding cofactor C) (CFC) Bos taurus (Bovine) post-chaperonin tubulin folding pathway [GO:0007023]; protein folding [GO:0006457]; tubulin complex assembly [GO:0007021] GO:0003924; GO:0005737; GO:0005829; GO:0006457; GO:0007021; GO:0007023; GO:0015631; GO:0032391 28487 XM_029328840.2 1177 1055 1197 1390 269 Q3ZC91 3.6e-41 Acid sphingomyelinase-like phosphodiesterase 3a (ASM-like phosphodiesterase 3a) (EC 3.1.4.-) Bos taurus (Bovine) nucleoside triphosphate catabolic process [GO:0009143] GO:0005576; GO:0005615; GO:0008081; GO:0008270; GO:0009143 28488 XM_029337399.2 0 7 0 114 0 Q06441 4.84e-174 Thrombospondin-4 Xenopus laevis (African clawed frog) cell adhesion [GO:0007155]; positive regulation of cell division [GO:0051781]; response to unfolded protein [GO:0006986] GO:0005509; GO:0005615; GO:0005783; GO:0006986; GO:0007155; GO:0008083; GO:0016529; GO:0051781; GO:0062023 28489 XM_044328231.1 0 4 4 7 16 NA NA NA NA NA NA 28490 XM_029344077.2 465 266 263 262 200 NA NA NA NA NA NA 28491 XR_006391977.1 157 128 146 227 341 NA NA NA NA NA NA 28492 XM_029339345.2 1217 1275 877 1221 1378 Q8LAD0 9.91e-53 Probable pyridoxal 5'-phosphate synthase subunit PDX2 (AtPDX2) (EC 4.3.3.6) (Protein EMBRYO DEFECTIVE 2407) (Pyridoxal 5'-phosphate synthase glutaminase subunit) (EC 3.5.1.2) Arabidopsis thaliana (Mouse-ear cress) glutamine metabolic process [GO:0006541]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine metabolic process [GO:0008614]; vitamin B6 biosynthetic process [GO:0042819] GO:0004359; GO:0005829; GO:0006541; GO:0008614; GO:0036381; GO:0042819; GO:0042823; GO:0046982; GO:1903600 28493 XM_044326747.1 113 8 10 73 220 NA NA NA NA NA NA 28494 XM_029334770.2 12 3 21 1 72 Q5VXJ0 6.48e-104 Lipase member K (EC 3.1.1.-) (Lipase-like abhydrolase domain-containing protein 2) Homo sapiens (Human) cornification [GO:0070268]; lipid catabolic process [GO:0016042] GO:0004465; GO:0005576; GO:0016042; GO:0043231; GO:0070268 28495 XM_029324321.2 2259 2032 1391 2130 3020 Q9EQX9 1.45e-81 Ubiquitin-conjugating enzyme E2 N (EC 2.3.2.23) (Bendless-like ubiquitin-conjugating enzyme) (E2 ubiquitin-conjugating enzyme N) (Ubiquitin carrier protein N) (Ubiquitin-protein ligase N) Rattus norvegicus (Rat) DNA double-strand break processing [GO:0000729]; double-strand break repair via homologous recombination [GO:0000724]; histone ubiquitination [GO:0016574]; positive regulation of DNA repair [GO:0045739]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of histone modification [GO:0031058]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of histone ubiquitination [GO:0033182]; T cell receptor signaling pathway [GO:0050852]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000151; GO:0000209; GO:0000724; GO:0000729; GO:0001650; GO:0004842; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006301; GO:0006511; GO:0016567; GO:0016574; GO:0031058; GO:0031372; GO:0031625; GO:0032991; GO:0033182; GO:0035370; GO:0043123; GO:0043130; GO:0045739; GO:0050852; GO:0051092; GO:0051443; GO:0061631; GO:0070534; GO:1902523; GO:1902533; GO:2000781 28496 XM_029325743.2 10 8 1 6 54 O70165 7.48e-72 Ficolin-1 (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin-alpha) (M-ficolin) Mus musculus (Mouse) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation, lectin pathway [GO:0001867]; G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of interleukin-8 production [GO:0032757] GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005581; GO:0005615; GO:0007186; GO:0030246; GO:0031232; GO:0032757; GO:0038187; GO:0046872; GO:0062023; GO:0097367 28497 XM_029327996.2 10 0 165 1355 2155 NA NA NA NA NA NA 28498 XM_029332222.2 5480 2976 2637 2741 2139 NA NA NA NA NA NA 28499 XR_006394752.1 5 1 5 4 13 NA NA NA NA NA NA 28500 XM_029351621.2 0 0 0 12 0 NA NA NA NA NA NA 28501 XM_029342128.2 585 155 519 703 646 P50429 3.38e-150 Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S) Mus musculus (Mouse) anterior head development [GO:0097065]; autophagy [GO:0006914]; central nervous system development [GO:0007417]; chondroitin sulfate catabolic process [GO:0030207]; colon epithelial cell migration [GO:0061580]; dermatan sulfate catabolic process [GO:0030209]; positive regulation of neuron projection development [GO:0010976]; regulation of epithelial cell migration [GO:0010632]; response to estrogen [GO:0043627]; response to methylmercury [GO:0051597]; response to nutrient [GO:0007584]; response to pH [GO:0009268] GO:0003943; GO:0004065; GO:0005739; GO:0005764; GO:0005791; GO:0005794; GO:0006914; GO:0007417; GO:0007584; GO:0008484; GO:0009268; GO:0009986; GO:0010632; GO:0010976; GO:0030207; GO:0030209; GO:0043627; GO:0043890; GO:0046872; GO:0051597; GO:0061580; GO:0097065 28502 XM_044318506.1 1 0 0 0 18 NA NA NA NA NA NA 28503 XM_029358408.2 98 469 66 755 69 Q9ULJ7 3.56e-51 Ankyrin repeat domain-containing protein 50 Homo sapiens (Human) endocytic recycling [GO:0032456]; protein transport [GO:0015031] GO:0005768; GO:0015031; GO:0032456 28504 XM_029358408.2 98 469 66 755 69 Q9ULJ7 3.92e-23 Ankyrin repeat domain-containing protein 50 Homo sapiens (Human) endocytic recycling [GO:0032456]; protein transport [GO:0015031] GO:0005768; GO:0015031; GO:0032456 28505 XM_029343034.2 894 1161 367 1141 545 NA NA NA NA NA NA 28506 XR_006393516.1 355 132 236 189 621 NA NA NA NA NA NA 28507 XM_044315597.1 138 0 0 8 0 Q4TU93 3.34e-30 C-type mannose receptor 2 (Endocytic receptor 180) (Macrophage mannose receptor 2) (CD antigen CD280) Rattus norvegicus (Rat) collagen catabolic process [GO:0030574]; endocytosis [GO:0006897] GO:0005518; GO:0005886; GO:0006897; GO:0030246; GO:0030574; GO:0038023 28508 XM_044315597.1 138 0 0 8 0 Q4TU93 2.31e-27 C-type mannose receptor 2 (Endocytic receptor 180) (Macrophage mannose receptor 2) (CD antigen CD280) Rattus norvegicus (Rat) collagen catabolic process [GO:0030574]; endocytosis [GO:0006897] GO:0005518; GO:0005886; GO:0006897; GO:0030246; GO:0030574; GO:0038023 28509 XM_044315597.1 138 0 0 8 0 Q4TU93 1.06e-23 C-type mannose receptor 2 (Endocytic receptor 180) (Macrophage mannose receptor 2) (CD antigen CD280) Rattus norvegicus (Rat) collagen catabolic process [GO:0030574]; endocytosis [GO:0006897] GO:0005518; GO:0005886; GO:0006897; GO:0030246; GO:0030574; GO:0038023 28510 XM_044313900.1 12 121 11 76 116 P35546 1.31e-81 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; anatomical structure morphogenesis [GO:0009653]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006919; GO:0007156; GO:0007158; GO:0007169; GO:0007399; GO:0009410; GO:0009653; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030182; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0098797; GO:2001241 28511 XM_044326954.1 0 41 12 13 17 NA NA NA NA NA NA 28512 XM_029357017.2 411 520 377 455 801 Q8WU76 3.57e-107 Sec1 family domain-containing protein 2 (Syntaxin-binding protein 1-like 1) Homo sapiens (Human) intracellular protein transport [GO:0006886]; vesicle docking involved in exocytosis [GO:0006904]; vesicle-mediated transport [GO:0016192] GO:0005886; GO:0006886; GO:0006904; GO:0016192; GO:0019905; GO:0030141 28513 XM_044314384.1 3 5 2 5 10 NA NA NA NA NA NA 28514 XM_044327278.1 2 12 0 4 6 NA NA NA NA NA NA 28515 XM_029342585.2 459 193 320 369 390 Q6WV17 2.77e-174 Polypeptide N-acetylgalactosaminyltransferase 5 (pp-GaNTase 5) (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 5) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 5) Drosophila melanogaster (Fruit fly) oligosaccharide biosynthetic process [GO:0009312]; protein O-linked glycosylation [GO:0006493] GO:0000139; GO:0004653; GO:0005794; GO:0005795; GO:0006493; GO:0009312; GO:0012505; GO:0030246; GO:0046872 28516 XM_029324630.2 1733 1960 1677 2004 3275 O57321 8.16e-123 Excitatory amino acid transporter 1 (SEAAT1) (Sodium-dependent glutamate/aspartate transporter) (GLAST) Ambystoma tigrinum (Eastern tiger salamander) chloride transmembrane transport [GO:1902476]; D-aspartate import across plasma membrane [GO:0070779]; L-aspartate import across plasma membrane [GO:0140009]; L-glutamate import across plasma membrane [GO:0098712]; potassium ion transmembrane transport [GO:0071805] GO:0005314; GO:0005886; GO:0015501; GO:0046872; GO:0070779; GO:0071805; GO:0098712; GO:0140009; GO:1902476 28517 XM_044312656.1 714 807 355 504 471 B5FYQ0 8.82e-74 ADP-ribosylation factor-like protein 3 Taeniopygia guttata (Zebra finch) (Poephila guttata) cilium assembly [GO:0060271]; Golgi to plasma membrane transport [GO:0006893]; intraciliary transport [GO:0042073]; kidney development [GO:0001822]; mitotic cytokinesis [GO:0000281]; photoreceptor cell development [GO:0042461]; protein localization to ciliary membrane [GO:1903441]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]; smoothened signaling pathway [GO:0007224] GO:0000139; GO:0000281; GO:0000287; GO:0001822; GO:0003924; GO:0005525; GO:0005634; GO:0005654; GO:0005794; GO:0005813; GO:0005876; GO:0005881; GO:0005929; GO:0005930; GO:0006893; GO:0007224; GO:0007264; GO:0008017; GO:0015031; GO:0019003; GO:0030496; GO:0032391; GO:0032794; GO:0036064; GO:0042073; GO:0042461; GO:0060271; GO:1903441 28518 XM_044326144.1 13 0 10 2 43 NA NA NA NA NA NA 28519 XM_044324750.1 42 35 74 57 34 Q9SSA4 2.23e-25 NA NA NA NA 28520 XM_029352264.2 15 0 0 0 6 NA NA NA NA NA NA 28521 XM_044310523.1 4 1 16 1253 2 NA NA NA NA NA NA 28522 XM_044311047.1 67 87 26 12 73 NA NA NA NA NA NA 28523 XM_044328884.1 0 0 11 26 0 P0CT40 9.12e-75 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 28524 XM_044315810.1 161 0 0 0 301 NA NA NA NA NA NA 28525 XM_029338253.2 379 250 70 160 161 Q7T3A4 6.59e-69 Ras-related protein Rab-13 Danio rerio (Zebrafish) (Brachydanio rerio) angiogenesis [GO:0001525]; bicellular tight junction assembly [GO:0070830]; cellular response to insulin stimulus [GO:0032869]; cortical actin cytoskeleton organization [GO:0030866]; endocytic recycling [GO:0032456]; endothelial cell chemotaxis [GO:0035767]; Golgi vesicle fusion to target membrane [GO:0048210]; neuron projection development [GO:0031175]; protein kinase A signaling [GO:0010737]; protein localization to cell leading edge [GO:1902463]; protein localization to plasma membrane [GO:0072659]; protein secretion [GO:0009306]; regulation of exocytosis [GO:0017157]; trans-Golgi network to recycling endosome transport [GO:0044795]; vesicle docking involved in exocytosis [GO:0006904] GO:0001525; GO:0003924; GO:0005525; GO:0005768; GO:0005802; GO:0005886; GO:0005923; GO:0006904; GO:0008021; GO:0009306; GO:0010737; GO:0016328; GO:0017157; GO:0030027; GO:0030139; GO:0030140; GO:0030866; GO:0031175; GO:0031410; GO:0032456; GO:0032593; GO:0032869; GO:0035767; GO:0043005; GO:0043231; GO:0044795; GO:0048210; GO:0055037; GO:0055038; GO:0070830; GO:0072659; GO:1902463 28526 XM_029350795.1 36 14 0 63 0 Q640F2 1.54e-79 SHC SH2 domain-binding protein 1 homolog B Xenopus laevis (African clawed frog) fibroblast growth factor receptor signaling pathway [GO:0008543]; regulation of neural precursor cell proliferation [GO:2000177] GO:0005737; GO:0005819; GO:0008543; GO:0030496; GO:2000177 28527 XM_044310476.1 170 120 70 118 216 NA NA NA NA NA NA 28528 XM_029346339.2 432 199 131 327 336 Q9Y6N9 1.18e-45 Harmonin (Antigen NY-CO-38/NY-CO-37) (Autoimmune enteropathy-related antigen AIE-75) (Protein PDZ-73) (Renal carcinoma antigen NY-REN-3) (Usher syndrome type-1C protein) Homo sapiens (Human) actin filament bundle assembly [GO:0051017]; brush border assembly [GO:1904970]; equilibrioception [GO:0050957]; G2/M transition of mitotic cell cycle [GO:0000086]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear morphogenesis [GO:0042472]; inner ear receptor cell stereocilium organization [GO:0060122]; parallel actin filament bundle assembly [GO:0030046]; photoreceptor cell maintenance [GO:0045494]; protein localization to microvillus [GO:1904106]; protein-containing complex assembly [GO:0065003]; regulation of microvillus length [GO:0032532]; retinal cone cell development [GO:0046549]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605] GO:0000086; GO:0001750; GO:0001917; GO:0002142; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0005902; GO:0005903; GO:0005929; GO:0007605; GO:0030046; GO:0030507; GO:0032420; GO:0032426; GO:0032532; GO:0042472; GO:0042491; GO:0045177; GO:0045202; GO:0045494; GO:0046549; GO:0050953; GO:0050957; GO:0051017; GO:0060122; GO:0065003; GO:1904106; GO:1904970 28529 XM_029350530.2 0 0 34 0 65 O42127 6.35e-59 Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) Xenopus laevis (African clawed frog) apoptotic process [GO:0006915]; positive regulation of cell population proliferation [GO:0008284] GO:0005007; GO:0005524; GO:0005886; GO:0006915; GO:0008284 28530 XM_044321103.1 10 65 5 10 274 NA NA NA NA NA NA 28531 XM_029336242.2 592 878 141 288 252 NA NA NA NA NA NA 28532 XM_029341786.2 8 0 0 5 0 Q75ZP8 5.26e-116 Pyranose 2-oxidase (P2Ox) (POD) (POx) (PROD) (Pyranose oxidase) (EC 1.1.3.10) (FAD-oxidoreductase) (Glucose 2-oxidase) (Pyranose:oxygen 2-oxidoreductase) Lyophyllum shimeji (Hon-shimeji) (Tricholoma shimeji) NA GO:0050233; GO:0050660 28533 XM_044328311.1 11 0 1 0 0 NA NA NA NA NA NA 28534 XM_029348443.1 89 45 54 53 76 NA NA NA NA NA NA 28535 XM_044327127.1 14 91 51 58 51 NA NA NA NA NA NA 28536 XR_006395854.1 92 22 16 83 40 NA NA NA NA NA NA 28537 XR_006395639.1 2 5 2 17 5 NA NA NA NA NA NA 28538 XM_044311333.1 1 4 1 2 393 O75051 0 Plexin-A2 (Semaphorin receptor OCT) Homo sapiens (Human) centrosome localization [GO:0051642]; cerebellar granule cell precursor tangential migration [GO:0021935]; limb bud formation [GO:0060174]; negative regulation of cell adhesion [GO:0007162]; neural tube development [GO:0021915]; pharyngeal system development [GO:0060037]; positive regulation of axonogenesis [GO:0050772]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; somitogenesis [GO:0001756] GO:0001756; GO:0002116; GO:0005886; GO:0007162; GO:0008360; GO:0017154; GO:0021915; GO:0021935; GO:0030334; GO:0042802; GO:0043087; GO:0050772; GO:0051642; GO:0060037; GO:0060174; GO:0071526; GO:1902287 28539 XM_044314736.1 65 18 61 33 94 NA NA NA NA NA NA 28540 XM_044314812.1 266 52 92 135 99 NA NA NA NA NA NA 28541 XM_044313457.1 126 106 68 91 77 NA NA NA NA NA NA 28542 XM_044318793.1 139 97 29 107 126 NA NA NA NA NA NA 28543 XM_029352890.2 877 582 479 881 340 Q9P2E2 1.84e-52 Kinesin-like protein KIF17 (KIF3-related motor protein) Homo sapiens (Human) anterograde dendritic transport of neurotransmitter receptor complex [GO:0098971]; cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] GO:0001750; GO:0001917; GO:0003777; GO:0005524; GO:0005815; GO:0005829; GO:0005871; GO:0005874; GO:0005929; GO:0005930; GO:0007018; GO:0008017; GO:0008574; GO:0015031; GO:0016192; GO:0016887; GO:0030030; GO:0032391; GO:0032839; GO:0036064; GO:0043005; GO:0098971; GO:1990075 28544 XM_029324729.2 22 20 41 42 5 P48630 2.34e-114 Omega-6 fatty acid desaturase, endoplasmic reticulum isozyme 1 (EC 1.14.19.-) Glycine max (Soybean) (Glycine hispida) unsaturated fatty acid biosynthetic process [GO:0006636] GO:0005789; GO:0006636; GO:0016491 28545 XR_003827388.2 22 44 38 34 34 NA NA NA NA NA NA 28546 XM_044320545.1 39 69 1 51 38 NA NA NA NA NA NA 28547 XM_044307108.1 70 0 42 23 211 NA NA NA NA NA NA 28548 XM_029326956.2 0 0 0 0 40 P27590 1.48e-33 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Rattus norvegicus (Rat) antibacterial innate immune response [GO:0140367]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; autophagy [GO:0006914]; calcium ion homeostasis [GO:0055074]; cellular calcium ion homeostasis [GO:0006874]; cellular chloride ion homeostasis [GO:0030644]; cellular phosphate ion homeostasis [GO:0030643]; cellular response to unfolded protein [GO:0034620]; cellular sodium ion homeostasis [GO:0006883]; chaperone-mediated protein folding [GO:0061077]; chemical homeostasis [GO:0048878]; chloride ion homeostasis [GO:0055064]; citric acid secretion [GO:0046720]; collecting duct development [GO:0072044]; connective tissue replacement [GO:0097709]; creatinine homeostasis [GO:0097273]; defense response to Gram-negative bacterium [GO:0050829]; endoplasmic reticulum organization [GO:0007029]; gene expression [GO:0010467]; glomerular filtration [GO:0003094]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; ion homeostasis [GO:0050801]; juxtaglomerular apparatus development [GO:0072051]; kidney development [GO:0001822]; leukocyte cell-cell adhesion [GO:0007159]; lipid metabolic process [GO:0006629]; loop of Henle development [GO:0072070]; metanephric ascending thin limb development [GO:0072218]; metanephric distal convoluted tubule development [GO:0072221]; metanephric thick ascending limb development [GO:0072233]; micturition [GO:0060073]; multicellular organismal homeostasis [GO:0048871]; multicellular organismal response to stress [GO:0033555]; neutrophil migration [GO:1990266]; organ or tissue specific immune response [GO:0002251]; peptidyl-threonine phosphorylation [GO:0018107]; phosphate ion homeostasis [GO:0055062]; potassium ion homeostasis [GO:0055075]; protein localization to vacuole [GO:0072665]; protein phosphorylation [GO:0006468]; protein transport into plasma membrane raft [GO:0044861]; regulation of blood pressure [GO:0008217]; regulation of protein transport [GO:0051223]; regulation of urine volume [GO:0035809]; renal sodium ion absorption [GO:0070294]; renal urate salt excretion [GO:0097744]; renal water homeostasis [GO:0003091]; response to endoplasmic reticulum stress [GO:0034976]; response to lipopolysaccharide [GO:0032496]; response to organic substance [GO:0010033]; response to unfolded protein [GO:0006986]; response to water deprivation [GO:0009414]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; sodium ion homeostasis [GO:0055078]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; ubiquitin-dependent ERAD pathway [GO:0030433]; urate transport [GO:0015747]; urea transmembrane transport [GO:0071918]; water homeostasis [GO:0030104] GO:0000922; GO:0001822; GO:0002251; GO:0003091; GO:0003094; GO:0005201; GO:0005509; GO:0005615; GO:0005783; GO:0005794; GO:0005886; GO:0005929; GO:0006468; GO:0006629; GO:0006874; GO:0006883; GO:0006914; GO:0006915; GO:0006954; GO:0006986; GO:0007029; GO:0007157; GO:0007159; GO:0008217; GO:0008380; GO:0009410; GO:0009414; GO:0009986; GO:0010033; GO:0010467; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0018107; GO:0019864; GO:0030104; GO:0030433; GO:0030643; GO:0030644; GO:0031410; GO:0032496; GO:0033209; GO:0033555; GO:0034620; GO:0034976; GO:0035809; GO:0044861; GO:0045121; GO:0045177; GO:0046720; GO:0048871; GO:0048878; GO:0050801; GO:0050829; GO:0051223; GO:0055062; GO:0055064; GO:0055074; GO:0055075; GO:0055078; GO:0060073; GO:0060170; GO:0061077; GO:0070294; GO:0071918; GO:0072044; GO:0072051; GO:0072070; GO:0072218; GO:0072221; GO:0072233; GO:0072665; GO:0097190; GO:0097273; GO:0097709; GO:0097744; GO:0140367; GO:1990266 28549 XR_003826339.2 132 117 46 220 206 NA NA NA NA NA NA 28550 XM_029332608.2 172 41 82 0 164 P49337 4.81e-67 Protein Wnt-4 Gallus gallus (Chicken) canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; kidney morphogenesis [GO:0060993]; negative regulation of androgen biosynthetic process [GO:2000180]; neuron differentiation [GO:0030182]; positive regulation of cartilage development [GO:0061036]; positive regulation of skeletal muscle cell proliferation [GO:0014858]; positive regulation of skeletal muscle fiber differentiation [GO:1902811] GO:0005109; GO:0005125; GO:0005615; GO:0005737; GO:0014858; GO:0030182; GO:0045165; GO:0060070; GO:0060993; GO:0061036; GO:1902811; GO:2000180 28551 XM_044327021.1 554 238 171 535 76 NA NA NA NA NA NA 28552 XM_044317873.1 64 4 8 49 70 Q96CG8 2.01e-42 Collagen triple helix repeat-containing protein 1 Homo sapiens (Human) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005576; GO:0005581; GO:0005615; GO:0016477; GO:0016528; GO:0017147; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0062023; GO:0090090; GO:0090103; GO:0090177 28553 XM_044317353.1 595 332 930 518 407 Q64604 6.14e-21 Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) (Leukocyte common antigen related) (LAR) Rattus norvegicus (Rat) cell migration [GO:0016477]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell projection organization [GO:0031345]; negative regulation of cytokine-mediated signaling pathway [GO:0001960]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of neurotrophin TRK receptor signaling pathway [GO:0051387]; negative regulation of receptor binding [GO:1900121]; nervous system development [GO:0007399]; neuron projection regeneration [GO:0031102]; peptidyl-tyrosine dephosphorylation [GO:0035335]; positive regulation of apoptotic process [GO:0043065]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of neuron apoptotic process [GO:0043525]; protein dephosphorylation [GO:0006470]; regulation of axon regeneration [GO:0048679]; regulation of neuron projection development [GO:0010975]; regulation of postsynapse organization [GO:0099175]; regulation of synapse structure or activity [GO:0050803]; synaptic membrane adhesion [GO:0099560] GO:0001960; GO:0004725; GO:0005001; GO:0005158; GO:0005768; GO:0005886; GO:0006470; GO:0007156; GO:0007399; GO:0008201; GO:0008285; GO:0010975; GO:0016020; GO:0016477; GO:0030426; GO:0030971; GO:0031102; GO:0031345; GO:0035335; GO:0035373; GO:0042059; GO:0042301; GO:0043005; GO:0043025; GO:0043065; GO:0043231; GO:0043525; GO:0044877; GO:0046627; GO:0048679; GO:0050775; GO:0050803; GO:0050839; GO:0051387; GO:0060076; GO:0098839; GO:0099175; GO:0099560; GO:1900121 28554 XM_044313078.1 296 153 142 556 121 NA NA NA NA NA NA 28555 XM_029327218.2 0 0 0 0 345 P47736 9.54e-114 Rap1 GTPase-activating protein 1 (Rap1GAP) (Rap1GAP1) Homo sapiens (Human) activation of GTPase activity [GO:0090630]; adaptive immune response [GO:0002250]; cellular response to glial cell derived neurotrophic factor [GO:1990792]; negative regulation of GTP binding [GO:1904425]; negative regulation of microvillus assembly [GO:1903697]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of thyroid gland epithelial cell proliferation [GO:1904442]; positive regulation of GTPase activity [GO:0043547]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] GO:0000139; GO:0002250; GO:0003924; GO:0005096; GO:0005737; GO:0005769; GO:0005829; GO:0007165; GO:0016020; GO:0030424; GO:0030425; GO:0031267; GO:0042803; GO:0043025; GO:0043087; GO:0043547; GO:0045665; GO:0051056; GO:0090630; GO:1903697; GO:1904425; GO:1904442; GO:1990792 28556 XR_006391295.1 26 2 24 63 50 NA NA NA NA NA NA 28557 XM_029333504.2 2226 1224 1577 2643 2056 NA NA NA NA NA NA 28558 XM_029332134.2 922 1655 991 954 515 NA NA NA NA NA NA 28559 XM_044320439.1 0 1 3 0 8 NA NA NA NA NA NA 28560 XM_029332371.2 90 45 155 294 338 Q6UB98 5.71e-34 Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein) Homo sapiens (Human) NA GO:0005654; GO:0005829 28561 XM_029338733.2 231 215 277 313 295 Q80TY4 1.32e-57 Suppression of tumorigenicity 18 protein Mus musculus (Mouse) interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6-mediated signaling pathway [GO:0070102]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000122; GO:0000977; GO:0000978; GO:0000981; GO:0003677; GO:0005634; GO:0006357; GO:0008270; GO:0008285; GO:0032993; GO:0033209; GO:0045944; GO:0070102; GO:0070498; GO:2001269 28562 XM_029338733.2 231 215 277 313 295 Q80TY4 8.97e-34 Suppression of tumorigenicity 18 protein Mus musculus (Mouse) interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6-mediated signaling pathway [GO:0070102]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000122; GO:0000977; GO:0000978; GO:0000981; GO:0003677; GO:0005634; GO:0006357; GO:0008270; GO:0008285; GO:0032993; GO:0033209; GO:0045944; GO:0070102; GO:0070498; GO:2001269 28563 XM_029338733.2 231 215 277 313 295 Q80TY4 7.8e-28 Suppression of tumorigenicity 18 protein Mus musculus (Mouse) interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6-mediated signaling pathway [GO:0070102]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000122; GO:0000977; GO:0000978; GO:0000981; GO:0003677; GO:0005634; GO:0006357; GO:0008270; GO:0008285; GO:0032993; GO:0033209; GO:0045944; GO:0070102; GO:0070498; GO:2001269 28564 XR_003825416.2 3 6 0 20 20 NA NA NA NA NA NA 28565 XM_029349334.2 0 0 33 349 98 NA NA NA NA NA NA 28566 XM_044317213.1 590 88 208 49 551 P08684 6.3e-95 Cytochrome P450 3A4 (EC 1.14.14.1) (1,4-cineole 2-exo-monooxygenase) (1,8-cineole 2-exo-monooxygenase) (EC 1.14.14.56) (Albendazole monooxygenase (sulfoxide-forming)) (EC 1.14.14.73) (Albendazole sulfoxidase) (CYPIIIA3) (CYPIIIA4) (Cholesterol 25-hydroxylase) (Cytochrome P450 3A3) (Cytochrome P450 HLp) (Cytochrome P450 NF-25) (Cytochrome P450-PCN1) (Nifedipine oxidase) (Quinine 3-monooxygenase) (EC 1.14.14.55) Homo sapiens (Human) aflatoxin metabolic process [GO:0046222]; alkaloid catabolic process [GO:0009822]; androgen metabolic process [GO:0008209]; cholesterol metabolic process [GO:0008203]; estrogen metabolic process [GO:0008210]; heterocycle metabolic process [GO:0046483]; lipid hydroxylation [GO:0002933]; lipid metabolic process [GO:0006629]; long-chain fatty acid biosynthetic process [GO:0042759]; monoterpenoid metabolic process [GO:0016098]; oxidative demethylation [GO:0070989]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]; steroid catabolic process [GO:0006706]; steroid metabolic process [GO:0008202]; vitamin D catabolic process [GO:0042369]; vitamin D metabolic process [GO:0042359]; xenobiotic catabolic process [GO:0042178]; xenobiotic metabolic process [GO:0006805] GO:0002933; GO:0004497; GO:0005496; GO:0005506; GO:0005737; GO:0005789; GO:0006629; GO:0006706; GO:0006805; GO:0008202; GO:0008203; GO:0008209; GO:0008210; GO:0008395; GO:0008401; GO:0009822; GO:0016098; GO:0016491; GO:0019825; GO:0019899; GO:0020037; GO:0030343; GO:0034875; GO:0042178; GO:0042359; GO:0042369; GO:0042572; GO:0042573; GO:0042759; GO:0043231; GO:0046222; GO:0046483; GO:0050591; GO:0050649; GO:0062181; GO:0062187; GO:0062188; GO:0062189; GO:0070330; GO:0070576; GO:0070989; GO:0101020; GO:0101021; GO:0102320 28567 XM_044314442.1 841 815 495 600 575 Q5F452 0 Myotubularin-related protein 8 (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64) Gallus gallus (Chicken) negative regulation of autophagy [GO:0010507]; phosphatidylinositol dephosphorylation [GO:0046856] GO:0004438; GO:0005635; GO:0010507; GO:0046856; GO:0052629; GO:0106018 28568 XM_044307059.1 0 3 0 8 0 NA NA NA NA NA NA 28569 XM_029356924.2 29 6 0 20 18 NA NA NA NA NA NA 28570 XM_044311965.1 0 0 0 0 10 NA NA NA NA NA NA 28571 XM_029323564.2 139 413 257 57 97 O95050 6.42e-33 Indolethylamine N-methyltransferase (Indolamine N-methyltransferase) (EC 2.1.1.49) (EC 2.1.1.96) (Aromatic alkylamine N-methyltransferase) (Amine N-methyltransferase) (Arylamine N-methyltransferase) (Thioether S-methyltransferase) (TEMT) Homo sapiens (Human) amine metabolic process [GO:0009308]; methylation [GO:0032259]; response to toxic substance [GO:0009636] GO:0004790; GO:0005829; GO:0008170; GO:0009308; GO:0009636; GO:0030748; GO:0032259; GO:0102707 28572 XM_029335410.2 508 440 387 585 606 Q61103 1.22e-82 Zinc finger protein ubi-d4 (Apoptosis response zinc finger protein) (BRG1-associated factor 45D) (BAF45D) (D4, zinc and double PHD fingers family 2) (Protein requiem) Mus musculus (Mouse) apoptotic process [GO:0006915]; chromatin remodeling [GO:0006338]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of myeloid progenitor cell differentiation [GO:1905454]; nervous system development [GO:0007399]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of G0 to G1 transition [GO:0070316]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of nucleotide-excision repair [GO:2000819]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000785; GO:0003712; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0005829; GO:0006338; GO:0006357; GO:0006915; GO:0007399; GO:0016514; GO:0030071; GO:0042393; GO:0043231; GO:0045892; GO:0045944; GO:0046872; GO:0062072; GO:0070316; GO:0070577; GO:0071565; GO:1902459; GO:1905454; GO:2000045; GO:2000781; GO:2000819 28573 XM_029341669.2 8991 7700 5269 8529 8247 Q04861 3.03e-40 Nuclear factor NF-kappa-B p105 subunit (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit] Gallus gallus (Chicken) regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165] GO:0000978; GO:0000981; GO:0005634; GO:0005737; GO:0006357; GO:0007165; GO:0051059 28574 XR_006393822.1 4 0 3 16 0 NA NA NA NA NA NA 28575 XM_044325836.1 34 21 34 4 171 NA NA NA NA NA NA 28576 XM_029341118.2 17 27 14 29 19 Q28509 6.52e-21 Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor) Macaca mulatta (Rhesus macaque) activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; bone resorption [GO:0045453]; brown fat cell differentiation [GO:0050873]; cellular response to amyloid-beta [GO:1904646]; desensitization of G protein-coupled receptor signaling pathway by arrestin [GO:0002032]; diet induced thermogenesis [GO:0002024]; heat generation [GO:0031649]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of smooth muscle contraction [GO:0045986]; norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0002025]; positive regulation of AMPA receptor activity [GO:2000969]; positive regulation of autophagosome maturation [GO:1901098]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of lipophagy [GO:1904504]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mini excitatory postsynaptic potential [GO:0061885]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor-mediated endocytosis [GO:0006898]; regulation of sodium ion transport [GO:0002028]; response to cold [GO:0009409]; smooth muscle contraction [GO:0006939]; transcription by RNA polymerase II [GO:0006366] GO:0001540; GO:0002024; GO:0002025; GO:0002028; GO:0002032; GO:0004930; GO:0004941; GO:0005634; GO:0005769; GO:0005794; GO:0005886; GO:0006366; GO:0006898; GO:0006939; GO:0007190; GO:0008179; GO:0009409; GO:0010739; GO:0015459; GO:0016324; GO:0030501; GO:0031649; GO:0040015; GO:0042803; GO:0043235; GO:0043410; GO:0044877; GO:0045453; GO:0045944; GO:0045986; GO:0050873; GO:0051380; GO:0061885; GO:0071880; GO:0071902; GO:0098992; GO:0120162; GO:1901098; GO:1904504; GO:1904646; GO:2000969 28577 XR_006392565.1 53 31 71 182 170 NA NA NA NA NA NA 28578 XM_029357502.2 638 570 116 519 985 NA NA NA NA NA NA 28579 XM_044312918.1 0 372 0 0 69 P15374 1.08e-90 Ubiquitin carboxyl-terminal hydrolase isozyme L3 (UCH-L3) (EC 3.4.19.12) (Ubiquitin thioesterase L3) Homo sapiens (Human) post-translational protein modification [GO:0043687]; protein catabolic process [GO:0030163]; protein deubiquitination [GO:0016579]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004843; GO:0005654; GO:0005737; GO:0005829; GO:0006511; GO:0008233; GO:0016567; GO:0016579; GO:0019784; GO:0030163; GO:0043130; GO:0043687 28580 XM_029336302.2 12 0 2 22 7 Q8BJ56 1.64e-72 Patatin-like phospholipase domain-containing protein 2 (EC 3.1.1.3) (Adipose triglyceride lipase) (Calcium-independent phospholipase A2-zeta) (iPLA2-zeta) (EC 3.1.1.4) (Desnutrin) Mus musculus (Mouse) cellular lipid catabolic process [GO:0044242]; diacylglycerol biosynthetic process [GO:0006651]; lipid droplet disassembly [GO:1905691]; lipid droplet organization [GO:0034389]; lipid homeostasis [GO:0055088]; lipid storage [GO:0019915]; negative regulation of sequestering of triglyceride [GO:0010891]; positive regulation of triglyceride catabolic process [GO:0010898]; triglyceride catabolic process [GO:0019433] GO:0004623; GO:0004806; GO:0005654; GO:0005737; GO:0005811; GO:0005829; GO:0005886; GO:0006651; GO:0010891; GO:0010898; GO:0016020; GO:0016411; GO:0019433; GO:0019915; GO:0034389; GO:0044242; GO:0050253; GO:0051264; GO:0051265; GO:0055088; GO:1905691 28581 XR_006393384.1 0 0 18 0 0 NA NA NA NA NA NA 28582 XM_029338333.2 38 26 38 37 38 Q54T82 1.37e-25 Putative leucine-rich repeat-containing protein DDB_G0281931 Dictyostelium discoideum (Social amoeba) NA GO:0016020 28583 XR_003826433.2 0 0 0 0 6 NA NA NA NA NA NA 28584 XR_006394567.1 36 7 92 59 37 NA NA NA NA NA NA 28585 XM_029355421.2 281 172 92 181 197 Q5RBX7 1.68e-28 Signal recognition particle 14 kDa protein (SRP14) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) SRP-dependent cotranslational protein targeting to membrane [GO:0006614] GO:0005786; GO:0006614; GO:0008312; GO:0030942 28586 XM_044320974.1 0 0 6 0 1 NA NA NA NA NA NA 28587 XM_044327284.1 7 61 21 4 40 NA NA NA NA NA NA 28588 XM_044324627.1 72 17 5 20 23 NA NA NA NA NA NA 28589 XR_006396404.1 292 195 75 99 299 Q27433 1.67e-112 Mechanosensory protein 2 Caenorhabditis elegans detection of mechanical stimulus involved in sensory perception of touch [GO:0050976]; mechanosensory behavior [GO:0007638]; positive regulation of detection of mechanical stimulus involved in sensory perception of touch [GO:1905789]; positive regulation of mechanosensory behavior [GO:1905792]; potassium ion transport [GO:0006813]; response to mechanical stimulus [GO:0009612] GO:0005272; GO:0005886; GO:0006813; GO:0007638; GO:0009612; GO:0015485; GO:0032589; GO:0043005; GO:0050976; GO:1905789; GO:1905792 28590 XM_029346034.2 0 12 2 2 0 O02824 8.1e-32 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) Oryctolagus cuniculus (Rabbit) adult heart development [GO:0007512]; cell growth involved in cardiac muscle cell development [GO:0061049]; MAPK cascade [GO:0000165]; multicellular organism aging [GO:0010259]; negative regulation of autophagy [GO:0010507]; negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure [GO:0001985]; neuron-glial cell signaling [GO:0150099]; norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001994]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; pilomotor reflex [GO:0097195]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of the force of heart contraction by epinephrine-norepinephrine [GO:0001997]; regulation of cardiac muscle contraction [GO:0055117]; regulation of vasoconstriction [GO:0019229] GO:0000165; GO:0001985; GO:0001994; GO:0001996; GO:0001997; GO:0004937; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0005901; GO:0007200; GO:0007512; GO:0010259; GO:0010507; GO:0010613; GO:0019229; GO:0031965; GO:0043410; GO:0045987; GO:0046982; GO:0055117; GO:0061049; GO:0097195; GO:0150099; GO:1903997 28591 XM_029328862.2 432 629 0 613 828 P18433 1.9e-169 Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (EC 3.1.3.48) Homo sapiens (Human) insulin receptor signaling pathway [GO:0008286]; integrin-mediated signaling pathway [GO:0007229]; modulation of chemical synaptic transmission [GO:0050804]; protein dephosphorylation [GO:0006470]; protein phosphorylation [GO:0006468]; regulation of focal adhesion assembly [GO:0051893] GO:0004725; GO:0005001; GO:0005886; GO:0005925; GO:0006468; GO:0006470; GO:0007229; GO:0008286; GO:0016020; GO:0043235; GO:0050804; GO:0051893; GO:0070062; GO:0097060; GO:0098685 28592 XM_029336378.2 668 393 474 612 452 Q9BUZ4 9.9e-83 TNF receptor-associated factor 4 (EC 2.3.2.27) (Cysteine-rich domain associated with RING and Traf domains protein 1) (Metastatic lymph node gene 62 protein) (MLN 62) (RING finger protein 83) Homo sapiens (Human) activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; innate immune response [GO:0045087]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein kinase activity [GO:0045860]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; respiratory gaseous exchange by respiratory system [GO:0007585]; respiratory tube development [GO:0030323] GO:0001650; GO:0005164; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0005923; GO:0006915; GO:0007250; GO:0007585; GO:0008270; GO:0016740; GO:0019901; GO:0030323; GO:0031625; GO:0031996; GO:0042802; GO:0042981; GO:0043122; GO:0043161; GO:0045087; GO:0045860; GO:0046330; GO:0048471; GO:0050699 28593 XM_029336378.2 668 393 474 612 452 Q9BUZ4 3.95e-37 TNF receptor-associated factor 4 (EC 2.3.2.27) (Cysteine-rich domain associated with RING and Traf domains protein 1) (Metastatic lymph node gene 62 protein) (MLN 62) (RING finger protein 83) Homo sapiens (Human) activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; innate immune response [GO:0045087]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein kinase activity [GO:0045860]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; respiratory gaseous exchange by respiratory system [GO:0007585]; respiratory tube development [GO:0030323] GO:0001650; GO:0005164; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0005923; GO:0006915; GO:0007250; GO:0007585; GO:0008270; GO:0016740; GO:0019901; GO:0030323; GO:0031625; GO:0031996; GO:0042802; GO:0042981; GO:0043122; GO:0043161; GO:0045087; GO:0045860; GO:0046330; GO:0048471; GO:0050699 28594 XM_029332364.2 5 21 6 11 11 NA NA NA NA NA NA 28595 XM_044318454.1 0 0 22 0 0 NA NA NA NA NA NA 28596 XR_006397428.1 66 157 73 73 324 NA NA NA NA NA NA 28597 XM_029354356.2 189 135 202 127 299 NA NA NA NA NA NA 28598 XM_044312401.1 23 0 0 100 0 NA NA NA NA NA NA 28599 XM_044321224.1 0 14 23 0 20 NA NA NA NA NA NA 28600 XR_006391329.1 0 1 43 17 14 NA NA NA NA NA NA 28601 XM_029343532.2 24 0 0 40 16 NA NA NA NA NA NA 28602 XM_029336325.2 121 70 131 126 174 NA NA NA NA NA NA 28603 XM_029334736.2 1833 1663 1691 2212 2177 P62484 4.61e-49 Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1) Mus musculus (Mouse) camera-type eye development [GO:0043010]; cell migration [GO:0016477]; dendrite development [GO:0016358]; learning or memory [GO:0007611]; lens fiber cell morphogenesis [GO:0070309]; neuron migration [GO:0001764]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of protein tyrosine kinase activity [GO:0061098]; postsynapse organization [GO:0099173]; postsynaptic actin cytoskeleton organization [GO:0098974]; Rac protein signal transduction [GO:0016601]; regulation of dendritic spine morphogenesis [GO:0061001]; zonula adherens assembly [GO:0045186] GO:0001764; GO:0005829; GO:0005884; GO:0005912; GO:0007611; GO:0010592; GO:0016358; GO:0016477; GO:0016601; GO:0017124; GO:0030027; GO:0030425; GO:0031209; GO:0031267; GO:0031625; GO:0032433; GO:0035591; GO:0042802; GO:0043010; GO:0043197; GO:0045186; GO:0061001; GO:0061098; GO:0070064; GO:0070309; GO:0098871; GO:0098974; GO:0098978; GO:0099173; GO:2000601 28604 XR_006397794.1 321 195 256 154 933 P04323 3.51e-26 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 28605 XR_006397794.1 321 195 256 154 933 P04323 3.51e-26 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 28606 XM_044314647.1 48 23 0 34 37 Q96AY4 4.06e-171 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28607 XM_044314647.1 48 23 0 34 37 Q96AY4 3.34e-159 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28608 XM_044314647.1 48 23 0 34 37 Q96AY4 2.11e-139 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28609 XM_044314647.1 48 23 0 34 37 Q96AY4 1.36e-130 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28610 XM_044314647.1 48 23 0 34 37 Q96AY4 6.39e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28611 XM_044322861.1 32 32 90 48 297 NA NA NA NA NA NA 28612 XR_006398146.1 47 8 139 61 331 NA NA NA NA NA NA 28613 XM_029352640.2 608 385 513 1455 759 NA NA NA NA NA NA 28614 XM_044308675.1 0 8 0 10 0 D3YXG0 1.23e-66 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 28615 XM_044308675.1 0 8 0 10 0 D3YXG0 6.87e-52 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 28616 XM_044308675.1 0 8 0 10 0 D3YXG0 1.46e-47 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 28617 XM_044308675.1 0 8 0 10 0 D3YXG0 5.3e-41 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 28618 XM_044308675.1 0 8 0 10 0 D3YXG0 6.44e-41 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 28619 XM_044308675.1 0 8 0 10 0 D3YXG0 1.33e-40 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 28620 XM_044308675.1 0 8 0 10 0 D3YXG0 3.05e-39 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 28621 XM_044308675.1 0 8 0 10 0 D3YXG0 3.65e-37 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 28622 XM_044308675.1 0 8 0 10 0 D3YXG0 9.24e-37 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 28623 XM_044308675.1 0 8 0 10 0 D3YXG0 1.12e-36 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 28624 XM_044308675.1 0 8 0 10 0 D3YXG0 2.32e-28 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 28625 XM_044308675.1 0 8 0 10 0 D3YXG0 1.18e-21 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 28626 XM_029323793.2 62 0 29 70 32 Q5F457 1.45e-23 WW domain-binding protein 4 (WBP-4) Gallus gallus (Chicken) mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380] GO:0000398; GO:0003723; GO:0005634; GO:0008270; GO:0008380; GO:0016607; GO:0071005; GO:0071011 28627 XR_006396600.1 25 17 0 23 0 Q29R99 1.24e-79 Putative lipoyltransferase 2, mitochondrial (EC 2.3.1.181) (Lipoate-protein ligase B) (Lipoyl/octanoyl transferase) (Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase) Danio rerio (Zebrafish) (Brachydanio rerio) positive regulation of oxygen metabolic process [GO:2000376]; protein lipoylation [GO:0009249] GO:0005739; GO:0009249; GO:0016874; GO:0033819; GO:2000376 28628 XM_044311450.1 221 240 80 221 261 NA NA NA NA NA NA 28629 XM_044322390.1 19 1 19 2 4 NA NA NA NA NA NA 28630 XM_029350691.2 1519 1156 984 2223 1607 Q8BPM2 0 Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5) Mus musculus (Mouse) intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468] GO:0004674; GO:0005524; GO:0005737; GO:0006468; GO:0008349; GO:0035556; GO:0106310 28631 XM_029351570.2 0 0 0 46 0 NA NA NA NA NA NA 28632 XM_044325811.1 178 37 38 115 174 NA NA NA NA NA NA 28633 XM_029327240.2 0 0 0 19 34 NA NA NA NA NA NA 28634 XM_029326825.2 643 471 347 529 761 O95453 1.95e-167 Poly(A)-specific ribonuclease PARN (EC 3.1.13.4) (Deadenylating nuclease) (Deadenylation nuclease) (Polyadenylate-specific ribonuclease) Homo sapiens (Human) box H/ACA RNA 3'-end processing [GO:0000495]; female gamete generation [GO:0007292]; miRNA catabolic process [GO:0010587]; ncRNA deadenylation [GO:0110008]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of telomerase RNA localization to Cajal body [GO:1904872]; RNA modification [GO:0009451]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; telomerase RNA stabilization [GO:0090669] GO:0000175; GO:0000184; GO:0000289; GO:0000495; GO:0003723; GO:0003730; GO:0004518; GO:0004535; GO:0005634; GO:0005730; GO:0005737; GO:0005829; GO:0007292; GO:0009451; GO:0010587; GO:0016607; GO:0019901; GO:0032212; GO:0043169; GO:0046872; GO:0051973; GO:0070034; GO:0071051; GO:0090503; GO:0090669; GO:0110008; GO:1904872 28635 XR_003827938.2 42 51 31 13 136 NA NA NA NA NA NA 28636 XM_044310134.1 24 0 0 13 5 Q3UQ28 3e-33 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 28637 XM_044310134.1 24 0 0 13 5 Q3UQ28 3.45e-28 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 28638 XR_006391675.1 667 370 441 845 870 P16621 5.34e-26 Tyrosine-protein phosphatase Lar (EC 3.1.3.48) (Protein-tyrosine-phosphate phosphohydrolase) (dLAR) Drosophila melanogaster (Fruit fly) axon extension [GO:0048675]; axon guidance [GO:0007411]; axon target recognition [GO:0007412]; cell adhesion [GO:0007155]; centripetally migrating follicle cell migration [GO:0060269]; hematopoietic stem cell homeostasis [GO:0061484]; motor neuron axon guidance [GO:0008045]; negative regulation of homophilic cell adhesion [GO:1903386]; negative regulation of insulin receptor signaling pathway [GO:0046627]; nervous system development [GO:0007399]; oogenesis [GO:0048477]; peptidyl-tyrosine dephosphorylation [GO:0035335]; photoreceptor cell morphogenesis [GO:0008594]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of plasma membrane bounded cell projection assembly [GO:0120034]; protein dephosphorylation [GO:0006470]; R7 cell development [GO:0045467]; regulation of axon extension involved in axon guidance [GO:0048841]; retinal ganglion cell axon guidance [GO:0031290]; spermatogenesis [GO:0007283]; synaptic assembly at neuromuscular junction [GO:0051124] GO:0004725; GO:0005001; GO:0005158; GO:0005925; GO:0006470; GO:0007155; GO:0007283; GO:0007399; GO:0007411; GO:0007412; GO:0008045; GO:0008201; GO:0008594; GO:0009925; GO:0009986; GO:0030424; GO:0031252; GO:0031290; GO:0032093; GO:0035335; GO:0045467; GO:0046627; GO:0048477; GO:0048675; GO:0048841; GO:0051124; GO:0051491; GO:0060269; GO:0061484; GO:0120034; GO:1903386 28639 XM_029331144.2 441 323 287 395 541 Q6DCC6 2.83e-106 Putative GTP-binding protein 6 Xenopus laevis (African clawed frog) NA GO:0005525; GO:0046872 28640 XM_029349240.2 93 48 25 160 121 Q92752 8.06e-70 Tenascin-R (TN-R) (Janusin) (Restrictin) Homo sapiens (Human) associative learning [GO:0008306]; axon extension involved in regeneration [GO:0048677]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198]; locomotory exploration behavior [GO:0035641]; long-term synaptic potentiation [GO:0060291]; negative regulation of axon extension involved in regeneration [GO:0048692]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of neuron projection development [GO:0010977]; negative regulation of synaptic transmission [GO:0050805]; neuroblast migration [GO:0097402]; neuromuscular process controlling balance [GO:0050885]; neuron cell-cell adhesion [GO:0007158]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transmission of nerve impulse [GO:0051971]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of cell migration [GO:0030334]; synapse organization [GO:0050808]; synaptic transmission, glutamatergic [GO:0035249]; telencephalon cell migration [GO:0022029] GO:0005102; GO:0005576; GO:0005615; GO:0007155; GO:0007158; GO:0007411; GO:0008306; GO:0009986; GO:0010977; GO:0022029; GO:0022408; GO:0030155; GO:0030198; GO:0030334; GO:0035249; GO:0035641; GO:0045121; GO:0045595; GO:0048677; GO:0048692; GO:0050805; GO:0050808; GO:0050885; GO:0051968; GO:0051971; GO:0060291; GO:0062023; GO:0072534; GO:0090733; GO:0097402; GO:0098685; GO:0098978 28641 XM_044328681.1 26 22 0 0 0 NA NA NA NA NA NA 28642 XM_029341074.2 391 223 25 814 223 Q3T052 4.31e-106 Inter-alpha-trypsin inhibitor heavy chain H4 (ITI heavy chain H4) (ITI-HC4) (Inter-alpha-inhibitor heavy chain 4) Bos taurus (Bovine) acute-phase response [GO:0006953]; hyaluronan metabolic process [GO:0030212]; negative regulation of peptidase activity [GO:0010466] GO:0004867; GO:0005576; GO:0006953; GO:0010466; GO:0030212 28643 XM_029341657.2 83 68 100 146 81 NA NA NA NA NA NA 28644 XM_029345401.2 0 0 0 18 0 Q9CYL5 4.26e-23 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Mus musculus (Mouse) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070374 28645 XM_044322077.1 118 0 0 45 33 Q8IZH2 0 5'-3' exoribonuclease 1 (EC 3.1.13.-) (Strand-exchange protein 1 homolog) Homo sapiens (Human) cellular response to cycloheximide [GO:0071409]; cellular response to puromycin [GO:1905795]; histone mRNA catabolic process [GO:0071044]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of translation [GO:0017148]; nuclear mRNA surveillance [GO:0071028]; nuclear-transcribed mRNA catabolic process [GO:0000956]; response to testosterone [GO:0033574]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; rRNA catabolic process [GO:0016075] GO:0000932; GO:0000956; GO:0002151; GO:0003723; GO:0004534; GO:0005634; GO:0005829; GO:0005886; GO:0016020; GO:0016075; GO:0017148; GO:0030425; GO:0032211; GO:0033574; GO:0043025; GO:0045202; GO:0051880; GO:0070034; GO:0071028; GO:0071044; GO:0071409; GO:0090503; GO:1905795 28646 XM_029351736.2 110 94 30 114 98 NA NA NA NA NA NA 28647 XR_003828590.2 4 2 6 0 0 NA NA NA NA NA NA 28648 XR_006397515.1 16 4 0 1 10 NA NA NA NA NA NA 28649 XM_029331578.2 1490 1088 1055 1650 1742 Q66L42 0 Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) Mus musculus (Mouse) cell death [GO:0008219]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA-templated transcription [GO:0045892]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of apoptotic process [GO:0043065]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; protein phosphorylation [GO:0006468]; smoothened signaling pathway [GO:0007224] GO:0003714; GO:0004672; GO:0004674; GO:0004706; GO:0005524; GO:0005737; GO:0006468; GO:0007224; GO:0008219; GO:0018105; GO:0018107; GO:0043065; GO:0043425; GO:0043433; GO:0043507; GO:0045892; GO:0046330; GO:0106310 28650 XM_029333354.2 606 92 481 540 618 NA NA NA NA NA NA 28651 XM_029356271.2 1693 711 972 1502 1898 A5HUI5 9.78e-163 Aminopeptidase A (AP-A) (APA) (EC 3.4.11.7) (Glutamyl aminopeptidase) (EAP) Gloydius brevicaudus (Korean slamosa snake) (Agkistrodon halys brevicaudus) proteolysis [GO:0006508] GO:0004177; GO:0005886; GO:0006508; GO:0008237; GO:0008270 28652 XM_029343434.2 0 115 339 0 288 Q99NH0 0 Ankyrin repeat domain-containing protein 17 (Ankyrin repeat domain-containing protein FOE) (Gene trap ankyrin repeat protein) Mus musculus (Mouse) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; endoderm development [GO:0007492]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0007492; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 28653 XM_029343434.2 0 115 339 0 288 Q99NH0 0 Ankyrin repeat domain-containing protein 17 (Ankyrin repeat domain-containing protein FOE) (Gene trap ankyrin repeat protein) Mus musculus (Mouse) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; endoderm development [GO:0007492]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0007492; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 28654 XM_029343434.2 0 115 339 0 288 Q99NH0 1.28e-51 Ankyrin repeat domain-containing protein 17 (Ankyrin repeat domain-containing protein FOE) (Gene trap ankyrin repeat protein) Mus musculus (Mouse) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; endoderm development [GO:0007492]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0007492; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 28655 XM_029343434.2 0 115 339 0 288 Q99NH0 2.87e-51 Ankyrin repeat domain-containing protein 17 (Ankyrin repeat domain-containing protein FOE) (Gene trap ankyrin repeat protein) Mus musculus (Mouse) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; endoderm development [GO:0007492]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0007492; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 28656 XM_029343434.2 0 115 339 0 288 Q99NH0 1.04e-49 Ankyrin repeat domain-containing protein 17 (Ankyrin repeat domain-containing protein FOE) (Gene trap ankyrin repeat protein) Mus musculus (Mouse) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; endoderm development [GO:0007492]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0007492; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 28657 XM_029343434.2 0 115 339 0 288 Q99NH0 3.49e-43 Ankyrin repeat domain-containing protein 17 (Ankyrin repeat domain-containing protein FOE) (Gene trap ankyrin repeat protein) Mus musculus (Mouse) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; endoderm development [GO:0007492]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0007492; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 28658 XM_029343434.2 0 115 339 0 288 Q99NH0 5.09e-43 Ankyrin repeat domain-containing protein 17 (Ankyrin repeat domain-containing protein FOE) (Gene trap ankyrin repeat protein) Mus musculus (Mouse) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; endoderm development [GO:0007492]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0007492; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 28659 XM_029343434.2 0 115 339 0 288 Q99NH0 1.02e-42 Ankyrin repeat domain-containing protein 17 (Ankyrin repeat domain-containing protein FOE) (Gene trap ankyrin repeat protein) Mus musculus (Mouse) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; endoderm development [GO:0007492]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0007492; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 28660 XM_029343434.2 0 115 339 0 288 Q99NH0 1e-39 Ankyrin repeat domain-containing protein 17 (Ankyrin repeat domain-containing protein FOE) (Gene trap ankyrin repeat protein) Mus musculus (Mouse) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; endoderm development [GO:0007492]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0007492; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 28661 XM_029343434.2 0 115 339 0 288 Q99NH0 1.89e-38 Ankyrin repeat domain-containing protein 17 (Ankyrin repeat domain-containing protein FOE) (Gene trap ankyrin repeat protein) Mus musculus (Mouse) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; endoderm development [GO:0007492]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0007492; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 28662 XM_029343434.2 0 115 339 0 288 Q99NH0 4.33e-34 Ankyrin repeat domain-containing protein 17 (Ankyrin repeat domain-containing protein FOE) (Gene trap ankyrin repeat protein) Mus musculus (Mouse) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; endoderm development [GO:0007492]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0007492; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 28663 XM_029343434.2 0 115 339 0 288 Q99NH0 6.88e-34 Ankyrin repeat domain-containing protein 17 (Ankyrin repeat domain-containing protein FOE) (Gene trap ankyrin repeat protein) Mus musculus (Mouse) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; endoderm development [GO:0007492]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0007492; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 28664 XM_029343434.2 0 115 339 0 288 Q99NH0 2.1e-31 Ankyrin repeat domain-containing protein 17 (Ankyrin repeat domain-containing protein FOE) (Gene trap ankyrin repeat protein) Mus musculus (Mouse) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; endoderm development [GO:0007492]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0007492; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 28665 XM_029343434.2 0 115 339 0 288 Q99NH0 1.8e-23 Ankyrin repeat domain-containing protein 17 (Ankyrin repeat domain-containing protein FOE) (Gene trap ankyrin repeat protein) Mus musculus (Mouse) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; endoderm development [GO:0007492]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0007492; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 28666 XM_044319744.1 1174 524 378 553 924 Q9D9I4 6.82e-102 TBC1 domain family member 20 Mus musculus (Mouse) acrosome assembly [GO:0001675]; camera-type eye development [GO:0043010]; COPII-coated vesicle cargo loading [GO:0090110]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; lens development in camera-type eye [GO:0002088]; lens fiber cell morphogenesis [GO:0070309]; lipid droplet organization [GO:0034389]; male gonad development [GO:0008584]; positive regulation by host of viral genome replication [GO:0044829]; positive regulation by virus of viral protein levels in host cell [GO:0046726]; positive regulation of ER to Golgi vesicle-mediated transport [GO:1902953]; positive regulation of GTPase activity [GO:0043547]; seminiferous tubule development [GO:0072520]; spermatogenesis [GO:0007283]; virion assembly [GO:0019068] GO:0000139; GO:0001675; GO:0002088; GO:0005096; GO:0005783; GO:0005789; GO:0006888; GO:0007030; GO:0007283; GO:0008584; GO:0019068; GO:0031267; GO:0031965; GO:0034389; GO:0043010; GO:0043547; GO:0044829; GO:0046726; GO:0070309; GO:0072520; GO:0090110; GO:1902953 28667 XR_006397672.1 0 0 16 16 20 NA NA NA NA NA NA 28668 XM_044307593.1 839 399 48 285 632 Q08C93 1.12e-74 Lysophosphatidylserine lipase ABHD12 (EC 3.1.-.-) (2-arachidonoylglycerol hydrolase ABHD12) (Abhydrolase domain-containing protein 12) (Monoacylglycerol lipase ABHD12) (EC 3.1.1.23) (Oxidized phosphatidylserine lipase ABHD12) (EC 3.1.-.-) Danio rerio (Zebrafish) (Brachydanio rerio) acylglycerol catabolic process [GO:0046464]; anterior lateral line development [GO:0048899]; camera-type eye development [GO:0043010]; monoacylglycerol catabolic process [GO:0052651]; myelination [GO:0042552]; phosphatidylserine catabolic process [GO:0006660]; phospholipid catabolic process [GO:0009395]; posterior lateral line neuromast development [GO:0048919]; retina layer formation [GO:0010842]; swimming behavior [GO:0036269] GO:0004620; GO:0004622; GO:0005789; GO:0006660; GO:0008474; GO:0009395; GO:0010842; GO:0016020; GO:0036269; GO:0042552; GO:0043010; GO:0046464; GO:0047372; GO:0048899; GO:0048919; GO:0052651 28669 XM_029339632.2 86 78 81 134 126 NA NA NA NA NA NA 28670 XM_044328082.1 0 0 7 15 0 NA NA NA NA NA NA 28671 XM_044325597.1 0 0 0 0 87 NA NA NA NA NA NA 28672 XR_006393641.1 271 550 493 372 322 NA NA NA NA NA NA 28673 XM_044317891.1 243 162 0 0 0 A7RFA1 2.39e-163 Phosphotriesterase-related protein (EC 3.1.-.-) (Parathion hydrolase-related protein) Nematostella vectensis (Starlet sea anemone) catabolic process [GO:0009056] GO:0008270; GO:0009056; GO:0016787 28674 XM_044321960.1 226 46 143 107 88 Q8K3Z0 3.32e-32 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 28675 XR_006397592.1 394 379 262 448 457 P30883 0 Tubulin beta-4 chain Xenopus laevis (African clawed frog) microtubule-based process [GO:0007017] GO:0003924; GO:0005200; GO:0005525; GO:0005737; GO:0005874; GO:0007017; GO:0046872 28676 XR_006397592.1 394 379 262 448 457 P30883 0 Tubulin beta-4 chain Xenopus laevis (African clawed frog) microtubule-based process [GO:0007017] GO:0003924; GO:0005200; GO:0005525; GO:0005737; GO:0005874; GO:0007017; GO:0046872 28677 XM_044320738.1 14 1 2 4 12 NA NA NA NA NA NA 28678 XR_006392685.1 254 24 139 11 207 NA NA NA NA NA NA 28679 XM_044325458.1 430 262 351 686 267 O73888 1.31e-23 Hematopoietic prostaglandin D synthase (H-PGDS) (EC 5.3.99.2) (GST class-sigma) (Glutathione S-transferase) (EC 2.5.1.18) (Glutathione-dependent PGD synthase) (Glutathione-requiring prostaglandin D synthase) (Prostaglandin-H2 D-isomerase) Gallus gallus (Chicken) glutathione metabolic process [GO:0006749]; prostaglandin biosynthetic process [GO:0001516]; prostaglandin metabolic process [GO:0006693] GO:0000287; GO:0001516; GO:0004364; GO:0004667; GO:0005509; GO:0005737; GO:0006693; GO:0006749 28680 XM_029328058.2 0 0 0 0 31 NA NA NA NA NA NA 28681 XM_029323820.2 2032 816 859 1219 1635 Q26614 1.57e-71 Fibroblast growth factor receptor (SpFGFR) (EC 2.7.10.1) Strongylocentrotus purpuratus (Purple sea urchin) positive regulation of kinase activity [GO:0033674]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0004714; GO:0005007; GO:0005524; GO:0005886; GO:0007169; GO:0017134; GO:0033674; GO:0043235 28682 XM_044322211.1 37 0 0 0 0 NA NA NA NA NA NA 28683 XM_029327367.2 0 0 0 0 16 Q9D1A2 0 Cytosolic non-specific dipeptidase (EC 3.4.13.18) (CNDP dipeptidase 2) (Glutamate carboxypeptidase-like protein 1) (Threonyl dipeptidase) Mus musculus (Mouse) proteolysis [GO:0006508] GO:0004180; GO:0005654; GO:0005829; GO:0006508; GO:0008233; GO:0016805; GO:0046872; GO:0070573; GO:0103046 28684 XM_029330194.2 1495 1595 670 1136 1034 NA NA NA NA NA NA 28685 XM_029334518.2 3190 3180 2931 3996 4149 Q28EW0 2.97e-136 Transmembrane protein 87A Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0000139; GO:0032580 28686 XM_029340839.2 233 79 131 231 398 Q64732 2.34e-25 Forkhead box protein B1 (Transcription factor FKH-5) Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; axon target recognition [GO:0007412]; cell differentiation [GO:0030154]; cell migration in diencephalon [GO:0061381]; epithelial cell differentiation involved in mammary gland alveolus development [GO:0061030]; floor plate development [GO:0033504]; hypothalamus cell migration [GO:0021855]; inferior colliculus development [GO:0061379]; lactation [GO:0007595]; mammary gland lobule development [GO:0061377]; mammillary body development [GO:0021767]; mammillothalamic axonal tract development [GO:0061374]; midbrain development [GO:0030901]; negative regulation of neuron apoptotic process [GO:0043524]; regulation of transcription by RNA polymerase II [GO:0006357]; somitogenesis [GO:0001756]; spinal cord development [GO:0021510]; telencephalon cell migration [GO:0022029]; thalamus development [GO:0021794]; urogenital system development [GO:0001655]; visual learning [GO:0008542] GO:0000978; GO:0000981; GO:0001655; GO:0001756; GO:0005634; GO:0006357; GO:0007412; GO:0007595; GO:0008542; GO:0009653; GO:0021510; GO:0021767; GO:0021794; GO:0021855; GO:0022029; GO:0030154; GO:0030901; GO:0033504; GO:0043524; GO:0043565; GO:0061030; GO:0061374; GO:0061377; GO:0061379; GO:0061381; GO:1990837 28687 XM_029323725.2 342 392 126 208 243 NA NA NA NA NA NA 28688 XM_044325511.1 0 3 1 7 2 NA NA NA NA NA NA 28689 XM_029348715.2 105 0 49 0 0 Q2KHM9 4.8e-21 Protein moonraker (MNR) (OFD1- and FOPNL-interacting protein) Homo sapiens (Human) centriole replication [GO:0007099]; cilium assembly [GO:0060271]; cytosolic ciliogenesis [GO:0061824]; protein localization to centrosome [GO:0071539] GO:0005813; GO:0005814; GO:0005829; GO:0007099; GO:0034451; GO:0046872; GO:0051537; GO:0060271; GO:0061824; GO:0071539 28690 XR_006393748.1 98 38 44 24 131 NA NA NA NA NA NA 28691 XR_003822723.2 375 86 81 288 270 O94812 1.3e-122 BAI1-associated protein 3 (BAP3) (Brain-specific angiogenesis inhibitor I-associated protein 3) Homo sapiens (Human) dense core granule maturation [GO:1990502]; exocytosis [GO:0006887]; G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of neurotransmitter secretion [GO:0001956]; regulation of dense core granule exocytosis [GO:1905413]; regulation of synaptic transmission, GABAergic [GO:0032228]; retrograde transport, endosome to Golgi [GO:0042147] GO:0000149; GO:0001956; GO:0005509; GO:0005543; GO:0005829; GO:0005886; GO:0006887; GO:0007186; GO:0019905; GO:0031902; GO:0032228; GO:0032588; GO:0035774; GO:0042147; GO:0055038; GO:0098793; GO:0099503; GO:1905413; GO:1990502 28692 XR_006393401.1 54 46 67 45 68 NA NA NA NA NA NA 28693 XM_044327037.1 111 18 65 0 155 A2AS55 5.29e-68 Ankyrin repeat domain-containing protein 16 Mus musculus (Mouse) tRNA modification [GO:0006400] GO:0005634; GO:0005737; GO:0006400 28694 XM_044326032.1 2 0 0 7 1 Q96AY4 1.41e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28695 XM_029344713.2 1489 897 784 1436 1654 F1QB30 2.92e-162 NA NA NA NA 28696 XM_029343465.2 62 46 27 50 67 NA NA NA NA NA NA 28697 XM_044318368.1 0 11 0 0 0 NA NA NA NA NA NA 28698 XM_029357846.2 1072 582 1055 1252 1020 Q8BH75 2.27e-35 E3 ubiquitin-protein ligase NRDP1 (EC 2.3.2.27) (RING finger protein 41) (RING-type E3 ubiquitin transferase NRDP1) Mus musculus (Mouse) autophagy [GO:0006914]; extrinsic apoptotic signaling pathway [GO:0097191]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of mitophagy [GO:1901525]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; proteasomal protein catabolic process [GO:0010498]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of lymphocyte differentiation [GO:0045619]; regulation of MAPK cascade [GO:0043408]; regulation of myeloid cell differentiation [GO:0045637]; regulation of protein kinase B signaling [GO:0051896]; regulation of reactive oxygen species metabolic process [GO:2000377] GO:0000209; GO:0004842; GO:0005128; GO:0005135; GO:0006914; GO:0008270; GO:0008285; GO:0010498; GO:0016567; GO:0019904; GO:0030336; GO:0030971; GO:0031267; GO:0042802; GO:0043408; GO:0045619; GO:0045637; GO:0045732; GO:0048471; GO:0051865; GO:0051896; GO:0061630; GO:0071782; GO:0097191; GO:1901525; GO:2000377; GO:2000379 28699 XM_029335797.2 54 96 59 109 54 NA NA NA NA NA NA 28700 XM_029326679.2 1034 787 484 836 611 NA NA NA NA NA NA 28701 XM_044308267.1 500 134 160 284 227 Q5ZLX5 1.65e-58 Zinc finger Ran-binding domain-containing protein 2 Gallus gallus (Chicken) RNA processing [GO:0006396] GO:0001530; GO:0003723; GO:0005634; GO:0006396; GO:0046872 28702 XM_029347698.2 365 268 295 210 311 Q2KI79 8.96e-37 Ankyrin repeat family A protein 2 Bos taurus (Bovine) regulation of gene expression [GO:0010468]; regulation of protein-containing complex assembly [GO:0043254] GO:0005634; GO:0005829; GO:0005856; GO:0010468; GO:0016020; GO:0019901; GO:0031625; GO:0042826; GO:0043254; GO:0050750; GO:1990393 28703 XM_044329129.1 1267 685 948 875 1492 Q96DB5 2.56e-73 Regulator of microtubule dynamics protein 1 (RMD-1) (hRMD-1) (Protein FAM82B) Homo sapiens (Human) attachment of mitotic spindle microtubules to kinetochore [GO:0051315]; mitotic spindle organization [GO:0007052] GO:0005737; GO:0005876; GO:0007052; GO:0008017; GO:0051315; GO:0097431 28704 XM_044324722.1 27 8 43 11 10 NA NA NA NA NA NA 28705 XR_006394513.1 1941 1295 1370 2777 2862 O35066 7.38e-37 Kinesin-like protein KIF3C Mus musculus (Mouse) microtubule-based movement [GO:0007018]; positive regulation of neuron projection development [GO:0010976] GO:0003777; GO:0005524; GO:0005829; GO:0005871; GO:0005874; GO:0007018; GO:0008017; GO:0008021; GO:0010976; GO:0015630; GO:0016020; GO:0016887; GO:0019894; GO:0030424; GO:0030425; GO:0030426; GO:0035371; GO:0043025; GO:0071598 28706 XM_029343233.2 253 51 0 152 357 O35972 9.15e-32 39S ribosomal protein L23, mitochondrial (L23mt) (MRP-L23) (L23 mitochondrial-related protein) Mus musculus (Mouse) mitochondrial translation [GO:0032543]; translation [GO:0006412] GO:0001650; GO:0003735; GO:0005739; GO:0005743; GO:0005762; GO:0006412; GO:0032543 28707 XM_029347143.2 179 33 3261 136 79 NA NA NA NA NA NA 28708 XR_006394502.1 3 126 23 58 3 NA NA NA NA NA NA 28709 XM_029328722.2 430 359 294 297 138 O88845 9.56e-84 A-kinase anchor protein 10, mitochondrial (AKAP-10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2) (Protein kinase A-anchoring protein 10) (PRKA10) Mus musculus (Mouse) protein localization [GO:0008104] GO:0005739; GO:0005829; GO:0005886; GO:0008104; GO:0032991; GO:0051018 28710 XM_029346333.2 22 87 16 135 73 E7FAM5 2.44e-89 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 28711 XM_044317289.1 301 180 143 226 232 Q9CXR1 5.3e-73 Dehydrogenase/reductase SDR family member 7 (EC 1.1.1.-) (Retinal short-chain dehydrogenase/reductase 4) (retSDR4) (Short chain dehydrogenase/reductase family 34C member 1) (Protein SDR34C1) Mus musculus (Mouse) NA GO:0004090; GO:0005789; GO:0016616; GO:0052650 28712 XM_029336434.2 2018 1442 1380 4404 3404 NA NA NA NA NA NA 28713 XM_044320343.1 22 0 0 88 0 P22607 3.5e-99 Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333) Homo sapiens (Human) bone maturation [GO:0070977]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cell-cell signaling [GO:0007267]; chondrocyte differentiation [GO:0002062]; chondrocyte proliferation [GO:0035988]; endochondral bone growth [GO:0003416]; endochondral ossification [GO:0001958]; fibroblast growth factor receptor apoptotic signaling pathway [GO:1902178]; fibroblast growth factor receptor signaling pathway [GO:0008543]; MAPK cascade [GO:0000165]; negative regulation of developmental growth [GO:0048640]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein autophosphorylation [GO:0046777]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0000165; GO:0001501; GO:0001958; GO:0002062; GO:0003416; GO:0004713; GO:0004714; GO:0005007; GO:0005524; GO:0005576; GO:0005634; GO:0005783; GO:0005794; GO:0005886; GO:0007169; GO:0007267; GO:0008284; GO:0008543; GO:0009986; GO:0010518; GO:0017134; GO:0018108; GO:0030133; GO:0030282; GO:0033674; GO:0035988; GO:0042531; GO:0042802; GO:0043235; GO:0043410; GO:0043552; GO:0046777; GO:0048640; GO:0060349; GO:0070374; GO:0070977; GO:1902178 28714 XM_044316014.1 16 106 1 0 145 NA NA NA NA NA NA 28715 XR_006397751.1 0 9 8 7 2 NA NA NA NA NA NA 28716 XM_029333703.2 3735 2960 2154 2001 1971 Q566C7 9.18e-44 Diphosphoinositol polyphosphate phosphohydrolase 1 (DIPP-1) (EC 3.6.1.52) (Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 1) (EC 3.6.1.-) (Nucleoside diphosphate-linked moiety X motif 3) (Nudix motif 3) Rattus norvegicus (Rat) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process [GO:1901911]; diadenosine hexaphosphate catabolic process [GO:1901909]; diadenosine pentaphosphate catabolic process [GO:1901907]; diphosphoinositol polyphosphate catabolic process [GO:0071544]; diphosphoinositol polyphosphate metabolic process [GO:0071543]; RNA decapping [GO:0110154] GO:0000287; GO:0000298; GO:0005634; GO:0005737; GO:0005829; GO:0008486; GO:0034431; GO:0034432; GO:0050072; GO:0052840; GO:0052842; GO:0052845; GO:0052848; GO:0071543; GO:0071544; GO:0110154; GO:1901907; GO:1901909; GO:1901911 28717 XM_029334860.2 37 33 6 6 7 NA NA NA NA NA NA 28718 XM_044313959.1 0 0 0 3 28 NA NA NA NA NA NA 28719 XM_044318379.1 122 60 176 1 158 P0CT39 3.11e-64 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 28720 XM_029356345.2 1072 1 332 866 744 Q8CIQ7 0 Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP) Mus musculus (Mouse) small GTPase mediated signal transduction [GO:0007264] GO:0005085; GO:0005096; GO:0005737; GO:0005829; GO:0005886; GO:0007264; GO:0017124; GO:0031267 28721 XM_029342845.2 1147 1146 874 807 110 P16444 4.38e-121 Dipeptidase 1 (EC 3.4.13.19) (Beta-lactamase) (EC 3.5.2.6) (Dehydropeptidase-I) (Microsomal dipeptidase) (Renal dipeptidase) (hRDP) Homo sapiens (Human) antibiotic metabolic process [GO:0016999]; cellular response to calcium ion [GO:0071277]; cellular response to nitric oxide [GO:0071732]; cellular response to xenobiotic stimulus [GO:0071466]; glutathione catabolic process [GO:0006751]; glutathione metabolic process [GO:0006749]; homocysteine metabolic process [GO:0050667]; inflammatory response [GO:0006954]; lactam catabolic process [GO:0072340]; leukotriene D4 catabolic process [GO:1901749]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell migration [GO:0030336]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; neutrophil chemotaxis [GO:0030593]; proteolysis [GO:0006508] GO:0005615; GO:0005654; GO:0005886; GO:0006508; GO:0006749; GO:0006751; GO:0006954; GO:0008235; GO:0008270; GO:0008800; GO:0016324; GO:0016805; GO:0016999; GO:0030054; GO:0030336; GO:0030593; GO:0031528; GO:0034235; GO:0043027; GO:0043066; GO:0043154; GO:0045177; GO:0050667; GO:0070062; GO:0070573; GO:0071277; GO:0071466; GO:0071732; GO:0072340; GO:0072341; GO:1901749 28722 XM_029328629.2 1226 636 650 416 535 C0QUB5 2.93e-80 GTPase Obg (EC 3.6.5.-) (GTP-binding protein Obg) Persephonella marina (strain DSM 14350 / EX-H1) ribosome biogenesis [GO:0042254] GO:0000287; GO:0003924; GO:0005525; GO:0005737; GO:0042254 28723 XM_044311617.1 6 0 0 0 2 NA NA NA NA NA NA 28724 XM_029340702.2 17819 17808 7987 15766 13709 O01727 1.89e-94 40S ribosomal protein S6 Branchiostoma floridae (Florida lancelet) (Amphioxus) translation [GO:0006412] GO:0003735; GO:0005840; GO:0006412; GO:1990904 28725 XM_029357684.2 466 986 795 924 1028 NA NA NA NA NA NA 28726 XM_044322831.1 66 10 5 4 139 NA NA NA NA NA NA 28727 XR_006394372.1 0 0 7 3 4 NA NA NA NA NA NA 28728 XM_044324882.1 193 230 141 435 587 Q8N3S3 1.34e-104 Protein PHTF2 Homo sapiens (Human) NA GO:0005783; GO:0016020 28729 XM_029333161.2 6934 7325 4110 7027 5984 Q62421 1.79e-89 Endophilin-A3 (Endophilin-3) (SH3 domain protein 2C) (SH3 domain-containing GRB2-like protein 3) (SH3p13) Mus musculus (Mouse) negative regulation of clathrin-dependent endocytosis [GO:1900186]; positive regulation of neuron differentiation [GO:0045666]; regulation of clathrin-dependent endocytosis [GO:2000369]; synaptic vesicle uncoating [GO:0016191] GO:0001669; GO:0005737; GO:0005769; GO:0008022; GO:0008289; GO:0016191; GO:0031901; GO:0042802; GO:0045202; GO:0045666; GO:0098793; GO:0098845; GO:0098978; GO:0099092; GO:1900186; GO:2000369 28730 XR_003828585.2 41 44 11 62 9 NA NA NA NA NA NA 28731 XM_044326422.1 0 0 1 0 9 NA NA NA NA NA NA 28732 XM_029355467.2 1735 1730 1172 1913 2072 Q7ZVN5 0 Signal recognition particle subunit SRP54 (EC 3.6.5.-) (Signal recognition particle 54 kDa protein) Danio rerio (Zebrafish) (Brachydanio rerio) exocrine pancreas development [GO:0031017]; granulocyte differentiation [GO:0030851]; neutrophil chemotaxis [GO:0030593]; SRP-dependent cotranslational protein targeting to membrane, translocation [GO:0006616] GO:0003924; GO:0005525; GO:0005786; GO:0005829; GO:0006616; GO:0008312; GO:0016607; GO:0030593; GO:0030851; GO:0030942; GO:0031017 28733 XM_044321421.1 158 35 124 84 216 NA NA NA NA NA NA 28734 XM_044322194.1 4 0 38 13 1 Q94887 1.67e-32 Neurexin-4 (Neurexin IV) Drosophila melanogaster (Fruit fly) axon ensheathment [GO:0008366]; cell adhesion involved in heart morphogenesis [GO:0061343]; cell-cell junction organization [GO:0045216]; dorsal closure [GO:0007391]; establishment of glial blood-brain barrier [GO:0060857]; heart process [GO:0003015]; nerve maturation [GO:0021682]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]; synaptic target recognition [GO:0008039]; terminal button organization [GO:0072553] GO:0003015; GO:0005886; GO:0005919; GO:0007391; GO:0008039; GO:0008104; GO:0008366; GO:0019991; GO:0021682; GO:0035151; GO:0045202; GO:0045216; GO:0048786; GO:0060857; GO:0061343; GO:0072553; GO:0097105 28735 XM_044327031.1 421 184 238 384 389 Q8NFZ0 4.56e-143 F-box DNA helicase 1 (hFBH1) (EC 5.6.2.4) (DNA 3'-5' helicase 1) (F-box only protein 18) Homo sapiens (Human) cell death [GO:0008219]; cellular response to DNA damage stimulus [GO:0006974]; DNA catabolic process, endonucleolytic [GO:0000737]; double-strand break repair via homologous recombination [GO:0000724]; negative regulation of chromatin binding [GO:0035562]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902231]; positive regulation of protein phosphorylation [GO:0001934]; protein ubiquitination [GO:0016567]; recombinational repair [GO:0000725]; replication fork processing [GO:0031297]; replication fork protection [GO:0048478]; response to intra-S DNA damage checkpoint signaling [GO:0072429] GO:0000724; GO:0000725; GO:0000737; GO:0000785; GO:0001934; GO:0003678; GO:0003690; GO:0003697; GO:0005524; GO:0005634; GO:0006974; GO:0008219; GO:0015616; GO:0016567; GO:0016887; GO:0019005; GO:0031297; GO:0035562; GO:0043138; GO:0048478; GO:0072429; GO:1902231; GO:2000042 28736 XM_044325248.1 114 60 68 91 180 NA NA NA NA NA NA 28737 XM_044309541.1 8 0 12 13 1 NA NA NA NA NA NA 28738 XM_044307091.1 1894 1355 1274 1436 1173 Q8CEE7 1.18e-70 Retinol dehydrogenase 13 (EC 1.1.1.300) Mus musculus (Mouse) eye photoreceptor cell development [GO:0042462]; response to high light intensity [GO:0009644]; retina layer formation [GO:0010842]; retinal metabolic process [GO:0042574] GO:0005739; GO:0005743; GO:0009644; GO:0010842; GO:0042462; GO:0042574; GO:0052650 28739 XM_029358387.2 84 2 11 6 255 Q9U3S9 1.57e-40 Zinc metalloproteinase nas-6 (EC 3.4.24.-) (Nematode astacin 6) Caenorhabditis elegans pharyngeal pumping [GO:0043050]; pharynx development [GO:0060465]; proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0006508; GO:0008270; GO:0043050; GO:0060465 28740 XM_044320324.1 74 237 84 223 0 NA NA NA NA NA NA 28741 XM_044327755.1 6 28 37 28 24 NA NA NA NA NA NA 28742 XM_029347481.2 0 9 1 10 2 NA NA NA NA NA NA 28743 XM_044320351.1 0 37 0 70 0 NA NA NA NA NA NA 28744 XM_044329040.1 651 587 210 352 91 NA NA NA NA NA NA 28745 XR_006392061.1 107 0 3 10 5 NA NA NA NA NA NA 28746 XM_029344479.2 1336 739 680 1016 1064 NA NA NA NA NA NA 28747 XM_044311246.1 0 18 1 0 12 NA NA NA NA NA NA 28748 XM_029352642.2 542 160 0 64 0 NA NA NA NA NA NA 28749 XM_029333582.2 29 43 42 33 24 NA NA NA NA NA NA 28750 XM_044324614.1 214 131 68 159 196 NA NA NA NA NA NA 28751 XR_006397278.1 0 0 0 38 0 NA NA NA NA NA NA 28752 XM_044320762.1 11 0 12 1 11 NA NA NA NA NA NA 28753 XM_044314699.1 51 25 47 25 99 Q7RTR2 3.48e-44 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 28754 XM_044314699.1 51 25 47 25 99 Q7RTR2 1.62e-39 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 28755 XM_044314699.1 51 25 47 25 99 Q7RTR2 1.03e-37 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 28756 XM_044314699.1 51 25 47 25 99 Q7RTR2 3.34e-24 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 28757 XM_029334794.2 25 44 33 14 31 NA NA NA NA NA NA 28758 XR_006392382.1 3346 2070 1981 2938 6321 P13595 8.79e-38 Neural cell adhesion molecule 1 (N-CAM-1) (NCAM-1) (CD antigen CD56) Mus musculus (Mouse) aging [GO:0007568]; axonal fasciculation [GO:0007413]; calcium-mediated signaling [GO:0019722]; cell surface receptor signaling pathway [GO:0007166]; commissural neuron axon guidance [GO:0071679]; homotypic cell-cell adhesion [GO:0034109]; learning or memory [GO:0007611]; modulation of chemical synaptic transmission [GO:0050804]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell death [GO:0060548]; neuron development [GO:0048666]; neuron projection development [GO:0031175]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; regulation of exocyst assembly [GO:0001928]; regulation of semaphorin-plexin signaling pathway [GO:2001260]; regulation of sensory perception of pain [GO:0051930]; response to cocaine [GO:0042220]; response to lead ion [GO:0010288]; response to xenobiotic stimulus [GO:0009410]; thalamus development [GO:0021794] GO:0001928; GO:0005829; GO:0005886; GO:0005911; GO:0007166; GO:0007413; GO:0007568; GO:0007611; GO:0008201; GO:0009410; GO:0009897; GO:0009986; GO:0010288; GO:0019722; GO:0019902; GO:0021794; GO:0030275; GO:0030424; GO:0030426; GO:0031175; GO:0033555; GO:0034109; GO:0042220; GO:0042734; GO:0043005; GO:0043025; GO:0043209; GO:0045211; GO:0048666; GO:0050804; GO:0050850; GO:0051930; GO:0060045; GO:0060548; GO:0071679; GO:0098685; GO:0098978; GO:2001260 28759 XR_006396949.1 0 12 23 8 17 NA NA NA NA NA NA 28760 XM_044309830.1 22 0 11 2 7 NA NA NA NA NA NA 28761 XM_029335814.2 5533 8374 712 589 765 NA NA NA NA NA NA 28762 XM_044326410.1 52 47 21 40 148 NA NA NA NA NA NA 28763 XM_029348026.2 288 29 206 142 72 NA NA NA NA NA NA 28764 XM_029329829.2 31 6 0 0 36 NA NA NA NA NA NA 28765 XM_029351978.2 642 746 266 430 535 B1WC40 1.62e-65 Nuclear cap-binding protein subunit 2 (20 kDa nuclear cap-binding protein) (NCBP 20 kDa subunit) (CBP20) Rattus norvegicus (Rat) histone mRNA metabolic process [GO:0008334]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transcription by RNA polymerase II [GO:0042789]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of mRNA 3'-end processing [GO:0031442]; positive regulation of RNA export from nucleus [GO:0046833]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; regulation of translational initiation [GO:0006446]; RNA splicing [GO:0008380]; RNA-mediated gene silencing [GO:0031047]; snRNA export from nucleus [GO:0006408] GO:0000184; GO:0000339; GO:0000340; GO:0000398; GO:0003677; GO:0003729; GO:0005634; GO:0005737; GO:0005845; GO:0005846; GO:0006406; GO:0006408; GO:0006446; GO:0008334; GO:0008380; GO:0017069; GO:0031047; GO:0031442; GO:0034518; GO:0042789; GO:0045292; GO:0046833; GO:0098789 28766 XM_044318346.1 57 49 40 76 66 Q8N539 8.28e-66 Fibrinogen C domain-containing protein 1 Homo sapiens (Human) cell adhesion [GO:0007155] GO:0005102; GO:0005615; GO:0007155; GO:0008061; GO:0016020; GO:0046872; GO:0062023 28767 XM_044318346.1 57 49 40 76 66 Q8N539 5.36e-62 Fibrinogen C domain-containing protein 1 Homo sapiens (Human) cell adhesion [GO:0007155] GO:0005102; GO:0005615; GO:0007155; GO:0008061; GO:0016020; GO:0046872; GO:0062023 28768 XM_029337900.2 17 9 0 36 11 NA NA NA NA NA NA 28769 XM_029346990.2 2054 1730 1113 1936 1417 Q5RDB5 2.66e-36 Protein cornichon homolog 1 (CNIH-1) (Cornichon family AMPA receptor auxiliary protein 1) (Protein cornichon homolog) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) vesicle-mediated transport [GO:0016192] GO:0000139; GO:0005789; GO:0016192 28770 XR_006392841.1 19 0 0 9 0 NA NA NA NA NA NA 28771 XM_029345103.2 150 86 64 48 109 Q6ZWL3 1.39e-154 Cytochrome P450 4V2 (Docosahexaenoic acid omega-hydroxylase CYP4V2) (EC 1.14.14.79) (Long-chain fatty acid omega-monooxygenase) (EC 1.14.14.80) Homo sapiens (Human) fatty acid omega-oxidation [GO:0010430]; response to stimulus [GO:0050896]; retinoid metabolic process [GO:0001523]; sterol metabolic process [GO:0016125]; visual perception [GO:0007601] GO:0001523; GO:0004497; GO:0005506; GO:0005789; GO:0007601; GO:0010430; GO:0016125; GO:0020037; GO:0050896; GO:0102033 28772 XM_029355967.2 275 96 125 285 187 NA NA NA NA NA NA 28773 XM_044317094.1 49 0 0 0 0 P11533 0 Dystrophin Gallus gallus (Chicken) actin filament bundle assembly [GO:0051017]; actin filament network formation [GO:0051639] GO:0005737; GO:0005884; GO:0008270; GO:0032432; GO:0042383; GO:0045211; GO:0051015; GO:0051017; GO:0051639; GO:0120025 28774 XM_044317094.1 49 0 0 0 0 P11533 7e-40 Dystrophin Gallus gallus (Chicken) actin filament bundle assembly [GO:0051017]; actin filament network formation [GO:0051639] GO:0005737; GO:0005884; GO:0008270; GO:0032432; GO:0042383; GO:0045211; GO:0051015; GO:0051017; GO:0051639; GO:0120025 28775 XM_044324737.1 5 0 44 0 0 NA NA NA NA NA NA 28776 XM_029343365.2 6323 4022 2130 3954 3384 NA NA NA NA NA NA 28777 XM_044313008.1 160 119 206 30 554 NA NA NA NA NA NA 28778 XM_029330769.2 83 0 0 0 64 D3ZR10 1.85e-26 Doublecortin domain-containing protein 2 Rattus norvegicus (Rat) cilium assembly [GO:0060271]; dendrite morphogenesis [GO:0048813]; intracellular signal transduction [GO:0035556]; neuron migration [GO:0001764]; neuronal action potential [GO:0019228]; positive regulation of smoothened signaling pathway [GO:0045880]; regulation of cilium assembly [GO:1902017]; regulation of Wnt signaling pathway [GO:0030111]; sensory perception of sound [GO:0007605]; synaptic transmission, glutamatergic [GO:0035249]; visual learning [GO:0008542] GO:0001764; GO:0005737; GO:0005815; GO:0005829; GO:0005856; GO:0005874; GO:0005929; GO:0005930; GO:0007605; GO:0008542; GO:0019228; GO:0019894; GO:0030111; GO:0034451; GO:0035249; GO:0035556; GO:0045202; GO:0045880; GO:0048813; GO:0060091; GO:0060271; GO:0072686; GO:1902017 28779 XM_029337365.2 173 48 97 82 62 Q9QYV8 0 DNA polymerase subunit gamma-1 (EC 2.7.7.7) (Mitochondrial DNA polymerase catalytic subunit) (PolG-alpha) Rattus norvegicus (Rat) aging [GO:0007568]; base-excision repair, gap-filling [GO:0006287]; cellular response to glucose stimulus [GO:0071333]; DNA-templated DNA replication [GO:0006261]; mitochondrial DNA replication [GO:0006264]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to light stimulus [GO:0009416] GO:0002020; GO:0003677; GO:0003682; GO:0003887; GO:0004527; GO:0005615; GO:0005730; GO:0005739; GO:0005759; GO:0005760; GO:0006261; GO:0006264; GO:0006287; GO:0007568; GO:0008408; GO:0009416; GO:0010332; GO:0032991; GO:0042645; GO:0043195; GO:0055093; GO:0071333; GO:0090305 28780 XR_006394709.1 2 1371 2 6 604 NA NA NA NA NA NA 28781 XM_044308417.1 78 50 24 87 82 E7FAM5 6.89e-60 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 28782 XR_006394640.1 6 0 13 4 9 NA NA NA NA NA NA 28783 XR_006393940.1 29 34 56 30 35 NA NA NA NA NA NA 28784 XM_029344930.2 4 17 2 3 6 NA NA NA NA NA NA 28785 XM_029328570.2 193 0 26 67 0 NA NA NA NA NA NA 28786 XM_029342441.2 156 119 97 103 357 NA NA NA NA NA NA 28787 XM_029349801.2 171 102 84 98 205 NA NA NA NA NA NA 28788 XM_044309871.1 27 2 17 0 42 NA NA NA NA NA NA 28789 XM_029339596.2 451 537 289 398 420 Q9W676 8e-139 LIM domain-binding protein 2 (LDB-2) (Carboxyl-terminal LIM domain-binding protein 1) (CLIM-1) (LIM domain-binding factor CLIM1) (cLdb2) Gallus gallus (Chicken) negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000122; GO:0005634; GO:0005667; GO:0007399; GO:0030274; GO:0045944 28790 XM_044314357.1 215 14 1358 150 1261 Q6LAF1 7.88e-46 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 28791 XM_044313738.1 2998 2061 1548 3229 3533 Q9W735 5.39e-85 Prominin-1-A (Prominin-like protein 1) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005783; GO:0005793; GO:0005886; GO:0005902; GO:0005929; GO:0009986; GO:0015485; GO:0016324; GO:0031528; GO:0071914 28792 XM_029324531.2 331 504 43 7 95 Q6P026 1.06e-46 Barrier-to-autointegration factor Danio rerio (Zebrafish) (Brachydanio rerio) chromatin organization [GO:0006325]; chromosome condensation [GO:0030261]; chromosome segregation [GO:0007059]; mitotic nuclear membrane reassembly [GO:0007084]; negative regulation of protein ADP-ribosylation [GO:0010836]; negative regulation of type I interferon production [GO:0032480]; response to oxidative stress [GO:0006979] GO:0000785; GO:0003677; GO:0005635; GO:0005654; GO:0005737; GO:0006325; GO:0006979; GO:0007059; GO:0007084; GO:0010836; GO:0030261; GO:0032480 28793 XM_029325796.2 47 20 97 3 79 NA NA NA NA NA NA 28794 XM_029344865.2 2327 1091 1215 2597 1262 NA NA NA NA NA NA 28795 XR_006396072.1 249 38 118 26 492 NA NA NA NA NA NA 28796 XM_044327590.1 257 42 388 619 7 NA NA NA NA NA NA 28797 XM_029342945.2 0 0 20 0 0 NA NA NA NA NA NA 28798 XR_003827714.2 0 37 18 886 0 NA NA NA NA NA NA 28799 XM_029356672.2 19 7 18 10 35 NA NA NA NA NA NA 28800 XM_029357812.2 789 400 121 678 1214 NA NA NA NA NA NA 28801 XM_044326456.1 89 28 46 56 117 NA NA NA NA NA NA 28802 XM_044321520.1 0 0 0 0 50 NA NA NA NA NA NA 28803 XM_029351038.2 191 90 83 87 103 Q8N4S7 2.6e-59 Progestin and adipoQ receptor family member 4 (Progestin and adipoQ receptor family member IV) Homo sapiens (Human) NA GO:0016020; GO:0038023 28804 XM_044328777.1 0 0 0 0 23 NA NA NA NA NA NA 28805 XM_044316467.1 0 0 9 27 0 NA NA NA NA NA NA 28806 XM_044310508.1 138 39 88 169 79 NA NA NA NA NA NA 28807 XM_044308167.1 82 54 33 117 82 P16066 1.59e-65 Atrial natriuretic peptide receptor 1 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type A) (ANP-A) (ANPR-A) (NPR-A) (Guanylate cyclase A) (GC-A) Homo sapiens (Human) blood vessel diameter maintenance [GO:0097746]; body fluid secretion [GO:0007589]; cell surface receptor signaling pathway [GO:0007166]; cGMP biosynthetic process [GO:0006182]; cGMP-mediated signaling [GO:0019934]; dopamine metabolic process [GO:0042417]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell growth [GO:0030308]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of cGMP-mediated signaling [GO:0010753]; positive regulation of renal sodium excretion [GO:0035815]; positive regulation of urine volume [GO:0035810]; protein phosphorylation [GO:0006468]; receptor guanylyl cyclase signaling pathway [GO:0007168]; regulation of blood pressure [GO:0008217]; regulation of vascular permeability [GO:0043114]; signal transduction [GO:0007165] GO:0001653; GO:0004383; GO:0004672; GO:0005524; GO:0005525; GO:0005886; GO:0006182; GO:0006468; GO:0007165; GO:0007166; GO:0007168; GO:0007589; GO:0008217; GO:0008528; GO:0010753; GO:0016525; GO:0016941; GO:0017046; GO:0019934; GO:0030308; GO:0035810; GO:0035815; GO:0042417; GO:0042562; GO:0043114; GO:0043235; GO:0048662; GO:0097746; GO:1990620 28808 XM_044316769.1 0 34 0 26 34 NA NA NA NA NA NA 28809 XM_044322117.1 921 1307 568 756 899 Q15435 3.57e-80 Protein phosphatase 1 regulatory subunit 7 (Protein phosphatase 1 regulatory subunit 22) Homo sapiens (Human) positive regulation of protein dephosphorylation [GO:0035307] GO:0000164; GO:0004865; GO:0005634; GO:0005694; GO:0005737; GO:0019888; GO:0030234; GO:0035307; GO:0070062 28810 XR_006394126.1 1 14 12 2 0 NA NA NA NA NA NA 28811 XM_029352360.2 105 42 271 420 431 O75581 0 Low-density lipoprotein receptor-related protein 6 (LRP-6) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; chemical synaptic transmission [GO:0007268]; dopaminergic neuron differentiation [GO:0071542]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001933; GO:0005041; GO:0005102; GO:0005109; GO:0005576; GO:0005783; GO:0005886; GO:0006469; GO:0007204; GO:0007268; GO:0009986; GO:0014029; GO:0014033; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0031410; GO:0031901; GO:0034392; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043434; GO:0044335; GO:0044340; GO:0045121; GO:0045202; GO:0045787; GO:0045893; GO:0045944; GO:0051091; GO:0060070; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072659; GO:0090118; GO:0090244; GO:0098609; GO:1904928; GO:1904948; GO:1904953; GO:1990851; GO:1990909 28812 XM_029352360.2 105 42 271 420 431 O75581 2.63e-176 Low-density lipoprotein receptor-related protein 6 (LRP-6) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; chemical synaptic transmission [GO:0007268]; dopaminergic neuron differentiation [GO:0071542]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001933; GO:0005041; GO:0005102; GO:0005109; GO:0005576; GO:0005783; GO:0005886; GO:0006469; GO:0007204; GO:0007268; GO:0009986; GO:0014029; GO:0014033; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0031410; GO:0031901; GO:0034392; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043434; GO:0044335; GO:0044340; GO:0045121; GO:0045202; GO:0045787; GO:0045893; GO:0045944; GO:0051091; GO:0060070; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072659; GO:0090118; GO:0090244; GO:0098609; GO:1904928; GO:1904948; GO:1904953; GO:1990851; GO:1990909 28813 XM_029324006.2 2221 2733 2191 2610 2641 Q9CZE3 5.91e-96 Ras-related protein Rab-32 Mus musculus (Mouse) antigen processing and presentation [GO:0019882]; endosome to melanosome transport [GO:0035646]; intracellular protein transport [GO:0006886]; melanosome assembly [GO:1903232]; melanosome organization [GO:0032438]; mitochondrion organization [GO:0007005]; phagosome maturation [GO:0090382]; protein localization to membrane [GO:0072657]; vesicle-mediated transport [GO:0016192] GO:0003924; GO:0005525; GO:0005739; GO:0005741; GO:0005769; GO:0005783; GO:0005802; GO:0006886; GO:0007005; GO:0012505; GO:0016020; GO:0016192; GO:0019882; GO:0030670; GO:0030742; GO:0032438; GO:0033162; GO:0035646; GO:0035650; GO:0035651; GO:0036461; GO:0042470; GO:0044233; GO:0045335; GO:0072657; GO:0090382; GO:1903232 28814 XM_029331858.2 12 34 62 90 23 NA NA NA NA NA NA 28815 XR_006398080.1 35 11 68 65 4 NA NA NA NA NA NA 28816 XM_029335244.2 202 155 158 145 185 Q5NDE7 2.12e-168 Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 (POMGnT2) (EC 2.4.1.312) (Extracellular O-linked N-acetylglucosamine transferase-like) (Glycosyltransferase-like domain-containing protein 2) Xenopus laevis (African clawed frog) neuron migration [GO:0001764]; protein O-linked glycosylation [GO:0006493]; protein O-linked mannosylation [GO:0035269] GO:0001764; GO:0005783; GO:0005789; GO:0006493; GO:0008375; GO:0035269 28817 XM_029334093.2 0 0 0 0 15 NA NA NA NA NA NA 28818 XM_044324039.1 436 193 285 819 245 Q5F364 0 Multidrug resistance-associated protein 1 (EC 7.6.2.2) (ATP-binding cassette sub-family C member 1) (Glutathione-S-conjugate-translocating ATPase ABCC1) (EC 7.6.2.3) (Leukotriene C(4) transporter) (LTC4 transporter) Gallus gallus (Chicken) glutathione transmembrane transport [GO:0034775]; lipid transport [GO:0006869]; transmembrane transport [GO:0055085]; xenobiotic transport [GO:0042908] GO:0005524; GO:0006869; GO:0008559; GO:0016020; GO:0016323; GO:0016887; GO:0034634; GO:0034775; GO:0042626; GO:0042908; GO:0055085 28819 XM_044315440.1 85 17 8 43 51 Q5DU56 2.22e-32 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 28820 XM_044315440.1 85 17 8 43 51 Q5DU56 5.05e-30 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 28821 XM_044315440.1 85 17 8 43 51 Q5DU56 7.44e-30 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 28822 XM_044315440.1 85 17 8 43 51 Q5DU56 2.51e-28 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 28823 XM_044315440.1 85 17 8 43 51 Q5DU56 5.67e-28 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 28824 XM_029348762.2 1644 1304 1085 2147 2666 Q9EQJ0 8.4e-142 Two pore calcium channel protein 1 (Voltage-dependent calcium channel protein TPC1) Mus musculus (Mouse) endocytosis involved in viral entry into host cell [GO:0075509]; positive regulation of autophagy [GO:0010508]; regulation of ion transmembrane transport [GO:0034765]; sodium ion transmembrane transport [GO:0035725] GO:0005244; GO:0005248; GO:0005765; GO:0010008; GO:0010508; GO:0015280; GO:0016020; GO:0019905; GO:0031901; GO:0034765; GO:0035725; GO:0036019; GO:0042802; GO:0042803; GO:0055038; GO:0072345; GO:0075509; GO:0080025; GO:0097682 28825 XM_044325800.1 12133 10147 6604 12512 12232 P29341 0 Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1) Mus musculus (Mouse) CRD-mediated mRNA stabilization [GO:0070934]; mRNA processing [GO:0006397]; negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900152]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cytoplasmic translation [GO:2000767]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; RNA splicing [GO:0008380]; RNA-mediated gene silencing [GO:0031047] GO:0000184; GO:0003723; GO:0003729; GO:0003730; GO:0005634; GO:0005737; GO:0005829; GO:0006397; GO:0008022; GO:0008143; GO:0008266; GO:0008380; GO:0010494; GO:0030027; GO:0030425; GO:0031047; GO:0031252; GO:0036464; GO:0045202; GO:0060213; GO:0070934; GO:0071013; GO:0106002; GO:1900152; GO:1900153; GO:1990124; GO:1990904; GO:2000623; GO:2000767 28826 XM_044325800.1 12133 10147 6604 12512 12232 P29341 2.32e-110 Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1) Mus musculus (Mouse) CRD-mediated mRNA stabilization [GO:0070934]; mRNA processing [GO:0006397]; negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900152]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cytoplasmic translation [GO:2000767]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; RNA splicing [GO:0008380]; RNA-mediated gene silencing [GO:0031047] GO:0000184; GO:0003723; GO:0003729; GO:0003730; GO:0005634; GO:0005737; GO:0005829; GO:0006397; GO:0008022; GO:0008143; GO:0008266; GO:0008380; GO:0010494; GO:0030027; GO:0030425; GO:0031047; GO:0031252; GO:0036464; GO:0045202; GO:0060213; GO:0070934; GO:0071013; GO:0106002; GO:1900152; GO:1900153; GO:1990124; GO:1990904; GO:2000623; GO:2000767 28827 XM_044325800.1 12133 10147 6604 12512 12232 P29341 3.13e-43 Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1) Mus musculus (Mouse) CRD-mediated mRNA stabilization [GO:0070934]; mRNA processing [GO:0006397]; negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900152]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cytoplasmic translation [GO:2000767]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; RNA splicing [GO:0008380]; RNA-mediated gene silencing [GO:0031047] GO:0000184; GO:0003723; GO:0003729; GO:0003730; GO:0005634; GO:0005737; GO:0005829; GO:0006397; GO:0008022; GO:0008143; GO:0008266; GO:0008380; GO:0010494; GO:0030027; GO:0030425; GO:0031047; GO:0031252; GO:0036464; GO:0045202; GO:0060213; GO:0070934; GO:0071013; GO:0106002; GO:1900152; GO:1900153; GO:1990124; GO:1990904; GO:2000623; GO:2000767 28828 XM_044325800.1 12133 10147 6604 12512 12232 P29341 2.7e-28 Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1) Mus musculus (Mouse) CRD-mediated mRNA stabilization [GO:0070934]; mRNA processing [GO:0006397]; negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900152]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cytoplasmic translation [GO:2000767]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; RNA splicing [GO:0008380]; RNA-mediated gene silencing [GO:0031047] GO:0000184; GO:0003723; GO:0003729; GO:0003730; GO:0005634; GO:0005737; GO:0005829; GO:0006397; GO:0008022; GO:0008143; GO:0008266; GO:0008380; GO:0010494; GO:0030027; GO:0030425; GO:0031047; GO:0031252; GO:0036464; GO:0045202; GO:0060213; GO:0070934; GO:0071013; GO:0106002; GO:1900152; GO:1900153; GO:1990124; GO:1990904; GO:2000623; GO:2000767 28829 XM_044325800.1 12133 10147 6604 12512 12232 P29341 1.02e-26 Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1) Mus musculus (Mouse) CRD-mediated mRNA stabilization [GO:0070934]; mRNA processing [GO:0006397]; negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900152]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cytoplasmic translation [GO:2000767]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; RNA splicing [GO:0008380]; RNA-mediated gene silencing [GO:0031047] GO:0000184; GO:0003723; GO:0003729; GO:0003730; GO:0005634; GO:0005737; GO:0005829; GO:0006397; GO:0008022; GO:0008143; GO:0008266; GO:0008380; GO:0010494; GO:0030027; GO:0030425; GO:0031047; GO:0031252; GO:0036464; GO:0045202; GO:0060213; GO:0070934; GO:0071013; GO:0106002; GO:1900152; GO:1900153; GO:1990124; GO:1990904; GO:2000623; GO:2000767 28830 XM_029335102.2 500 7 63 33 19 Q9Y6D9 7.45e-83 Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient 1-like protein 1) (MAD1-like protein 1) (Mitotic checkpoint MAD1 protein homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181) Homo sapiens (Human) attachment of mitotic spindle microtubules to kinetochore [GO:0051315]; cell division [GO:0051301]; cytoplasmic sequestering of protein [GO:0051220]; deactivation of mitotic spindle assembly checkpoint [GO:1902426]; mitotic spindle assembly checkpoint signaling [GO:0007094]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; regulation of metaphase plate congression [GO:0090235]; thymus development [GO:0048538] GO:0000776; GO:0000922; GO:0005634; GO:0005737; GO:0005813; GO:0005819; GO:0005829; GO:0007094; GO:0042130; GO:0042802; GO:0043515; GO:0044615; GO:0048538; GO:0051220; GO:0051301; GO:0051315; GO:0072686; GO:0090235; GO:0090267; GO:1902426; GO:1990706; GO:1990728 28831 XM_044307728.1 8367 3691 3678 6192 6016 Q9TTR8 4.89e-64 COUP transcription factor 1 (COUP-TF1) (COUP transcription factor I) (COUP-TF I) (Nuclear receptor subfamily 2 group F member 1) Bos taurus (Bovine) anatomical structure development [GO:0048856]; cell differentiation [GO:0030154]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000978; GO:0001227; GO:0004879; GO:0005654; GO:0005829; GO:0006357; GO:0008270; GO:0030154; GO:0045944; GO:0048856 28832 XM_029350827.2 1898 565 1015 428 546 Q8CIH9 0 Amidophosphoribosyltransferase (ATase) (EC 2.4.2.14) (Glutamine phosphoribosylpyrophosphate amidotransferase) (GPAT) Mus musculus (Mouse) 'de novo' AMP biosynthetic process [GO:0044208]; 'de novo' IMP biosynthetic process [GO:0006189]; 'de novo' XMP biosynthetic process [GO:0097294]; glutamine catabolic process [GO:0006543]; GMP biosynthetic process [GO:0006177]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; ribose phosphate metabolic process [GO:0019693] GO:0004044; GO:0006164; GO:0006177; GO:0006189; GO:0006543; GO:0009113; GO:0009168; GO:0019693; GO:0042802; GO:0044208; GO:0046872; GO:0051539; GO:0097294 28833 XM_029341075.2 1116 726 225 366 409 Q3T052 2.52e-106 Inter-alpha-trypsin inhibitor heavy chain H4 (ITI heavy chain H4) (ITI-HC4) (Inter-alpha-inhibitor heavy chain 4) Bos taurus (Bovine) acute-phase response [GO:0006953]; hyaluronan metabolic process [GO:0030212]; negative regulation of peptidase activity [GO:0010466] GO:0004867; GO:0005576; GO:0006953; GO:0010466; GO:0030212 28834 XM_044320790.1 9 0 13 1 63 NA NA NA NA NA NA 28835 XM_044317496.1 3 1 10 1 32 NA NA NA NA NA NA 28836 XM_029339197.2 114 68 48 46 120 P00532 5.86e-31 Serine/threonine-protein kinase-transforming protein raf (EC 2.7.11.1) Murine sarcoma virus 3611 protein phosphorylation [GO:0006468] GO:0004674; GO:0005524; GO:0006468; GO:0106310 28837 XR_003827527.2 11 0 0 0 0 Q5NDL0 3.51e-137 EGF domain-specific O-linked N-acetylglucosamine transferase (EC 2.4.1.255) (Extracellular O-linked N-acetylglucosamine transferase) Rattus norvegicus (Rat) protein O-GlcNAcylation via threonine [GO:0097370]; protein O-linked glycosylation [GO:0006493] GO:0005788; GO:0006493; GO:0008375; GO:0016262; GO:0016757; GO:0097363; GO:0097370 28838 XM_044320885.1 38 183 79 64 77 NA NA NA NA NA NA 28839 XM_044310334.1 22 4 10 0 14 NA NA NA NA NA NA 28840 XM_044322110.1 483 2811 1620 1016 8 Q5AXT5 3.21e-32 ATP-dependent DNA helicase PIF1 (EC 3.6.4.12) (DNA repair and recombination helicase PIF1) Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; mitochondrial genome maintenance [GO:0000002]; telomere maintenance [GO:0000723] GO:0000002; GO:0000723; GO:0003677; GO:0005524; GO:0005634; GO:0005657; GO:0005739; GO:0006260; GO:0006281; GO:0006310; GO:0016887; GO:0032508; GO:0043139 28841 XM_044310260.1 0 1 0 0 17 NA NA NA NA NA NA 28842 XM_029333377.2 372 522 178 883 632 NA NA NA NA NA NA 28843 XM_029327699.2 592 546 1779 918 0 Q96DM1 4.93e-53 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 28844 XM_029335349.2 249 248 186 496 433 NA NA NA NA NA NA 28845 XM_044309711.1 9 0 4 0 0 NA NA NA NA NA NA 28846 XM_029330313.2 821 994 887 2238 609 Q47898 1.6e-59 N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase (EC 3.5.1.26) (Aspartylglucosaminidase) (AGA) (Glycosylasparaginase) (N4-(N-acetyl-beta-glucosaminyl)-L-asparagine amidase) [Cleaved into: Glycosylasparaginase alpha chain; Glycosylasparaginase beta chain] Elizabethkingia miricola (Chryseobacterium miricola) proteolysis [GO:0006508] GO:0003948; GO:0006508; GO:0008233; GO:0042597 28847 XM_044328616.1 810 202 431 445 615 A0A0R4IBK5 0 E3 ubiquitin-protein ligase rnf213-alpha (EC 2.3.2.27) (EC 3.6.4.-) (E3 ubiquitin-lipopolysaccharide ligase rnf213-alpha) (EC 2.3.2.-) (Mysterin-A) (Mysterin-alpha) (RING finger protein 213-A) (RING finger protein 213-alpha) Danio rerio (Zebrafish) (Brachydanio rerio) blood circulation [GO:0008015]; defense response to bacterium [GO:0042742]; immune system process [GO:0002376]; lipid droplet formation [GO:0140042]; lipid ubiquitination [GO:0120323]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein K63-linked ubiquitination [GO:0070534]; regulation of lipid metabolic process [GO:0019216]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]; xenophagy [GO:0098792] GO:0002040; GO:0002376; GO:0004842; GO:0005524; GO:0005730; GO:0005811; GO:0005829; GO:0006511; GO:0008015; GO:0016887; GO:0019216; GO:0042742; GO:0046872; GO:0061630; GO:0070534; GO:0098792; GO:0120323; GO:0140042; GO:2000051 28848 XM_044328616.1 810 202 431 445 615 A0A0R4IBK5 7.35e-89 E3 ubiquitin-protein ligase rnf213-alpha (EC 2.3.2.27) (EC 3.6.4.-) (E3 ubiquitin-lipopolysaccharide ligase rnf213-alpha) (EC 2.3.2.-) (Mysterin-A) (Mysterin-alpha) (RING finger protein 213-A) (RING finger protein 213-alpha) Danio rerio (Zebrafish) (Brachydanio rerio) blood circulation [GO:0008015]; defense response to bacterium [GO:0042742]; immune system process [GO:0002376]; lipid droplet formation [GO:0140042]; lipid ubiquitination [GO:0120323]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein K63-linked ubiquitination [GO:0070534]; regulation of lipid metabolic process [GO:0019216]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]; xenophagy [GO:0098792] GO:0002040; GO:0002376; GO:0004842; GO:0005524; GO:0005730; GO:0005811; GO:0005829; GO:0006511; GO:0008015; GO:0016887; GO:0019216; GO:0042742; GO:0046872; GO:0061630; GO:0070534; GO:0098792; GO:0120323; GO:0140042; GO:2000051 28849 XM_029344519.2 15 5 13 12 10 NA NA NA NA NA NA 28850 XM_029341916.2 135 169 77 474 423 B8V7S0 9.38e-63 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 28851 XM_044322748.1 0 0 6 6 17 NA NA NA NA NA NA 28852 XM_044313358.1 128 168 63 315 307 A1WS32 1.88e-66 Putative hydro-lyase Veis_4744 (EC 4.2.1.-) Verminephrobacter eiseniae (strain EF01-2) NA GO:0016829 28853 XM_044311125.1 128 93 90 135 382 NA NA NA NA NA NA 28854 XM_029336732.2 397 319 160 320 293 Q6DFN1 1.72e-33 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) mitochondrial respiratory chain complex I assembly [GO:0032981] GO:0005634; GO:0005743; GO:0032981 28855 XM_029357125.2 1496 1655 1368 892 720 Q5TM57 1.31e-26 Ribonuclease P protein subunit p21 (RNaseP protein p21) Macaca mulatta (Rhesus macaque) tRNA processing [GO:0008033] GO:0004526; GO:0005655; GO:0008033; GO:0046872 28856 XM_044322835.1 11 0 36 137 0 Q5DU56 1.5e-25 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 28857 XM_044322835.1 11 0 36 137 0 Q5DU56 3.91e-22 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 28858 XM_029346984.2 14 0 8 0 32 NA NA NA NA NA NA 28859 XM_029334116.2 48 0 37 86 89 Q60547 5.51e-40 Synaptonemal complex protein 3 (SCP-3) (Meiotic chromosome core protein) (Synaptonemal complex protein COR1) Mesocricetus auratus (Golden hamster) cell division [GO:0051301]; meiotic cell cycle [GO:0051321] GO:0000775; GO:0000800; GO:0003677; GO:0005694; GO:0051301; GO:0051321 28860 XM_029343344.2 486 350 86 442 255 Q4U0T9 9.32e-32 Cysteine and glycine-rich protein 3 (Cysteine-rich protein 3) (CRP3) Bos taurus (Bovine) actin cytoskeleton organization [GO:0030036]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac myofibril assembly [GO:0055003]; cellular calcium ion homeostasis [GO:0006874]; detection of muscle stretch [GO:0035995]; glucose homeostasis [GO:0042593]; inflammatory response [GO:0006954]; insulin receptor signaling pathway [GO:0008286]; muscle cell cellular homeostasis [GO:0046716]; muscle organ development [GO:0007517]; muscle tissue development [GO:0060537]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein kinase C signaling [GO:0070528]; protein localization to organelle [GO:0033365]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of the force of heart contraction [GO:0002026]; sarcomere organization [GO:0045214]; T-tubule organization [GO:0033292] GO:0002026; GO:0003300; GO:0003779; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0006874; GO:0006954; GO:0007517; GO:0008286; GO:0008307; GO:0030018; GO:0030036; GO:0031433; GO:0033292; GO:0033365; GO:0035995; GO:0042593; GO:0042802; GO:0042805; GO:0045214; GO:0045944; GO:0046716; GO:0046872; GO:0055003; GO:0060048; GO:0060537; GO:0070528; GO:1903076 28861 XM_044319164.1 0 0 61 0 3 NA NA NA NA NA NA 28862 XM_029337130.2 1772 1319 723 1908 1748 Q8CFG5 1.59e-49 Voltage-dependent calcium channel subunit alpha-2/delta-3 (Voltage-gated calcium channel subunit alpha-2/delta-3) [Cleaved into: Voltage-dependent calcium channel subunit alpha-2-3; Voltage-dependent calcium channel subunit delta-3] Rattus norvegicus (Rat) calcium ion transport [GO:0006816]; cellular response to insulin-like growth factor stimulus [GO:1990314]; regulation of ion transmembrane transport [GO:0034765] GO:0005245; GO:0005246; GO:0005891; GO:0006816; GO:0034765; GO:0046872; GO:1990314 28863 XM_044324174.1 2780 2005 949 2510 1670 NA NA NA NA NA NA 28864 XM_044329070.1 93 241 29 0 0 Q9VPD3 7.08e-136 Phosphatidylserine synthase (EC 2.7.8.29) Drosophila melanogaster (Fruit fly) phosphatidylserine biosynthetic process [GO:0006659] GO:0005789; GO:0006659; GO:0012505; GO:0016780; GO:0106245; GO:0106258 28865 XM_044321395.1 34 17 52 14 66 B3EWZ5 1.75e-23 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 28866 XM_044321395.1 34 17 52 14 66 B3EWZ5 6.6e-23 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 28867 XM_044321395.1 34 17 52 14 66 B3EWZ5 8.23e-22 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 28868 XM_044321395.1 34 17 52 14 66 B3EWZ5 9.82e-22 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 28869 XM_044321395.1 34 17 52 14 66 B3EWZ5 3.41e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 28870 XM_044321395.1 34 17 52 14 66 B3EWZ5 3.77e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 28871 XM_029325335.2 86 94 0 1 122 P38487 0 Creatinase (EC 3.5.3.3) (Creatine amidinohydrolase) Bacillus sp. (strain B-0618) NA GO:0016980 28872 XM_044327469.1 120 30 2 21 0 NA NA NA NA NA NA 28873 XM_044328646.1 42 238 25 81 0 NA NA NA NA NA NA 28874 XM_044322561.1 0 18 72 148 83 P52569 9.91e-122 Cationic amino acid transporter 2 (CAT-2) (CAT2) (Low affinity cationic amino acid transporter 2) (Solute carrier family 7 member 2) Homo sapiens (Human) amino acid import across plasma membrane [GO:0089718]; amino acid transport [GO:0006865]; L-alpha-amino acid transmembrane transport [GO:1902475]; L-amino acid transport [GO:0015807]; L-arginine import across plasma membrane [GO:0097638]; L-arginine transmembrane transport [GO:1903826]; L-ornithine transmembrane transport [GO:1903352]; transport across blood-brain barrier [GO:0150104] GO:0000064; GO:0005886; GO:0006865; GO:0015171; GO:0015174; GO:0015179; GO:0015189; GO:0015807; GO:0030054; GO:0061459; GO:0089718; GO:0097638; GO:0150104; GO:1902475; GO:1903352; GO:1903826 28875 XM_029338169.2 1223 811 514 1475 1657 A5PJ65 5.72e-64 Protein RER1 Bos taurus (Bovine) localization [GO:0051179] GO:0000139; GO:0051179 28876 XM_044325238.1 7813 16720 8462 14811 11077 Q5R7J8 2.4e-70 Protein tyrosine phosphatase type IVA 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cell cycle [GO:0007049]; protein dephosphorylation [GO:0006470] GO:0004725; GO:0005634; GO:0005769; GO:0005783; GO:0005819; GO:0005886; GO:0006470; GO:0007049; GO:0008138 28877 XM_044325029.1 7 0 11 9 19 NA NA NA NA NA NA 28878 XM_029336555.2 2111 2398 1612 4546 1847 NA NA NA NA NA NA 28879 XM_044328845.1 0 84 30 0 0 Q6AX59 6.76e-70 Protein ABHD8 (EC 3.-.-.-) (Alpha/beta hydrolase domain-containing protein 8) (Abhydrolase domain-containing protein 8) Xenopus laevis (African clawed frog) NA GO:0016787 28880 XM_029329820.2 118 63 16 50 53 NA NA NA NA NA NA 28881 XM_044316754.1 3 0 10 0 22 NA NA NA NA NA NA 28882 XM_044327662.1 38 5 3 0 0 NA NA NA NA NA NA 28883 XM_029341767.2 19 5 2 14 40 NA NA NA NA NA NA 28884 XR_006392116.1 327 175 205 151 159 NA NA NA NA NA NA 28885 XM_029323780.2 473 397 247 341 324 Q99JW2 6.6e-173 Aminoacylase-1 (ACY-1) (EC 3.5.1.14) (N-acyl-L-amino-acid amidohydrolase) Mus musculus (Mouse) amino acid metabolic process [GO:0006520] GO:0004046; GO:0005737; GO:0006520; GO:0042802; GO:0046872; GO:0070062 28886 XM_029350377.2 238 162 107 154 213 NA NA NA NA NA NA 28887 XM_044311599.1 1 102 69 289 71 NA NA NA NA NA NA 28888 XM_029357145.2 192 254 343 538 736 NA NA NA NA NA NA 28889 XM_029334359.2 77 158 97 104 99 NA NA NA NA NA NA 28890 XM_029341577.2 1885 1515 924 1486 1530 NA NA NA NA NA NA 28891 XM_029345217.2 4268 2293 2182 2587 2887 P67963 0 Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1) Xenopus laevis (African clawed frog) cell cycle [GO:0007049]; cell division [GO:0051301]; intermediate filament cytoskeleton organization [GO:0045104]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; protein phosphorylation [GO:0006468]; Wnt signaling pathway [GO:0016055] GO:0000776; GO:0004674; GO:0005524; GO:0005737; GO:0005819; GO:0006468; GO:0007049; GO:0016055; GO:0016607; GO:0036064; GO:0045104; GO:0051301; GO:0106310; GO:1900226 28892 XR_003827625.1 2 7 2 9 4 NA NA NA NA NA NA 28893 XM_029342140.2 42 141 69 139 148 NA NA NA NA NA NA 28894 XM_029353243.2 251 261 389 533 351 Q680A5 1.77e-100 Ribose-phosphate pyrophosphokinase 4 (EC 2.7.6.1) (Phosphoribosyl pyrophosphate synthase 4) Arabidopsis thaliana (Mouse-ear cress) 5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; phosphorylation [GO:0016310]; purine nucleotide biosynthetic process [GO:0006164] GO:0000287; GO:0002189; GO:0004749; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006015; GO:0006164; GO:0009506; GO:0016301; GO:0016310 28895 XR_003828477.2 5 49 16 45 45 NA NA NA NA NA NA 28896 XM_044328197.1 302 420 291 400 566 NA NA NA NA NA NA 28897 XM_029341362.2 53 91 0 0 0 O16374 3.45e-28 Beta-1,4-galactosyltransferase galt-1 (EC 2.4.1.-) Caenorhabditis elegans N-glycan processing [GO:0006491]; protein galactosylation [GO:0042125] GO:0003831; GO:0006491; GO:0032580; GO:0035250; GO:0042125; GO:0043229; GO:0046872 28898 XM_029323478.2 1690 901 611 1479 1236 P33587 9.65e-38 Vitamin K-dependent protein C (EC 3.4.21.69) (Anticoagulant protein C) (Autoprothrombin IIA) (Blood coagulation factor XIV) [Cleaved into: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide] Mus musculus (Mouse) blood coagulation [GO:0007596]; liver development [GO:0001889]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood coagulation [GO:0030195]; negative regulation of coagulation [GO:0050819]; negative regulation of inflammatory response [GO:0050728]; positive regulation of establishment of endothelial barrier [GO:1903142]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of circulating fibrinogen levels [GO:0044537] GO:0001889; GO:0004252; GO:0005509; GO:0005615; GO:0005783; GO:0005794; GO:0006508; GO:0007596; GO:0008233; GO:0030163; GO:0030195; GO:0043066; GO:0043621; GO:0044537; GO:0050728; GO:0050819; GO:0070012; GO:1903142; GO:1905370 28899 XM_029331830.2 65 59 125 49 236 Q91VP7 3.73e-24 Transmembrane protein 101 Mus musculus (Mouse) NA GO:0016020 28900 XM_044314803.1 13 10 0 21 24 NA NA NA NA NA NA 28901 XM_044322617.1 67 326 184 162 254 Q6AZW2 6e-91 Aldo-keto reductase family 1 member A1-A (Alcohol dehydrogenase [NADP(+)] A) (EC 1.1.1.2) (Aldehyde reductase-A) Danio rerio (Zebrafish) (Brachydanio rerio) aldehyde catabolic process [GO:0046185]; cellular detoxification of aldehyde [GO:0110095] GO:0004032; GO:0005829; GO:0016324; GO:0046185; GO:0110095 28902 XR_006397080.1 58 81 55 78 29 NA NA NA NA NA NA 28903 XM_029344366.2 480 142 114 172 157 Q5XJ85 3.97e-28 Myeloid differentiation primary response protein MyD88 Danio rerio (Zebrafish) (Brachydanio rerio) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; monocyte activation [GO:0042117]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; neutrophil activation involved in immune response [GO:0002283]; neutrophil chemotaxis [GO:0030593]; positive regulation of hematopoietic progenitor cell differentiation [GO:1901534]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of hematopoietic progenitor cell differentiation [GO:1901532]; response to molecule of bacterial origin [GO:0002237]; Toll signaling pathway [GO:0008063] GO:0002218; GO:0002237; GO:0002283; GO:0002755; GO:0005737; GO:0005886; GO:0006954; GO:0008063; GO:0030593; GO:0035325; GO:0042117; GO:0042742; GO:0043123; GO:0045087; GO:0050830; GO:0070976; GO:1901532; GO:1901534 28904 XM_029358288.2 23 3 5 8 25 P98072 3.27e-53 Enteropeptidase (EC 3.4.21.9) (Enterokinase) (Serine protease 7) (Transmembrane protease serine 15) [Cleaved into: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain] Bos taurus (Bovine) protein digestion [GO:0044256]; trypsinogen activation [GO:0032023] GO:0004252; GO:0005044; GO:0016020; GO:0032023; GO:0044256 28905 XM_029323802.2 1400 798 719 1295 1126 Q7T2C4 8.06e-114 NA NA NA NA 28906 XM_029358385.2 44 33 43 212 36 NA NA NA NA NA NA 28907 XM_044327357.1 4 21 0 37 44 NA NA NA NA NA NA 28908 XM_029327414.2 685 921 344 491 319 Q567I9 5e-102 Cytochrome b5 domain-containing protein 1 Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0046872 28909 XM_029329140.2 1639 871 1032 1817 1569 NA NA NA NA NA NA 28910 XM_044322858.1 63 32 19 7 2 NA NA NA NA NA NA 28911 XM_044319638.1 1 34 3 16 6 NA NA NA NA NA NA 28912 XR_006395322.1 0 11 1 4 4 NA NA NA NA NA NA 28913 XM_029338786.2 205 107 102 217 235 NA NA NA NA NA NA 28914 XM_044311208.1 11 0 0 3 46 NA NA NA NA NA NA 28915 XM_044319376.1 20 16 10 2 4 NA NA NA NA NA NA 28916 XR_003826080.2 21 0 5 7 57 NA NA NA NA NA NA 28917 XM_044327458.1 11 48 11 89 15 F8J3H2 3.23e-24 NA NA NA NA 28918 XM_029346122.2 1302 737 775 1764 1326 Q3U3T8 0 WD repeat-containing protein 62 Mus musculus (Mouse) centriole replication [GO:0007099]; cerebral cortex development [GO:0021987]; mitotic spindle organization [GO:0007052]; neurogenesis [GO:0022008]; neuronal stem cell population maintenance [GO:0097150]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron migration [GO:2001224]; regulation of centrosome cycle [GO:0046605]; regulation of neuron differentiation [GO:0045664] GO:0000922; GO:0002052; GO:0005634; GO:0005813; GO:0005814; GO:0005829; GO:0007052; GO:0007099; GO:0021987; GO:0022008; GO:0034451; GO:0045664; GO:0046605; GO:0072686; GO:0097150; GO:2001224 28919 XM_044313775.1 562 193 154 269 308 P55115 6.38e-39 Zinc metalloproteinase nas-15 (EC 3.4.24.-) (Nematode astacin 15) Caenorhabditis elegans proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0006508; GO:0008270 28920 XM_044310097.1 0 0 143 217 248 NA NA NA NA NA NA 28921 XM_044320765.1 2 0 0 19 2 NA NA NA NA NA NA 28922 XM_029331970.2 585 923 0 2948 1775 D3YXG0 6.86e-102 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 28923 XM_029331970.2 585 923 0 2948 1775 D3YXG0 6.81e-100 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 28924 XM_029331970.2 585 923 0 2948 1775 D3YXG0 2.98e-96 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 28925 XM_029331970.2 585 923 0 2948 1775 D3YXG0 8.25e-93 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 28926 XM_029331970.2 585 923 0 2948 1775 D3YXG0 6.35e-92 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 28927 XM_029331970.2 585 923 0 2948 1775 D3YXG0 3.32e-87 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 28928 XM_029331970.2 585 923 0 2948 1775 D3YXG0 2.2e-71 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 28929 XM_029331970.2 585 923 0 2948 1775 D3YXG0 1.92e-61 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 28930 XM_029331970.2 585 923 0 2948 1775 D3YXG0 6.43e-40 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 28931 XM_029331970.2 585 923 0 2948 1775 D3YXG0 1.04e-39 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 28932 XM_044311934.1 2 22 57 18 79 NA NA NA NA NA NA 28933 XM_044319140.1 634 622 373 1401 0 NA NA NA NA NA NA 28934 XM_029344945.2 65 13 23 73 61 Q3URF8 5.02e-25 BTB/POZ domain-containing protein KCTD21 (KCASH2 protein) (Potassium channel tetramerization domain-containing protein 21) Mus musculus (Mouse) negative regulation of smoothened signaling pathway [GO:0045879]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0006511; GO:0016567; GO:0042802; GO:0042826; GO:0045879; GO:0051260; GO:0097602 28935 XM_044316411.1 0 8 0 0 1 Q03650 8.83e-72 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 28936 XM_044316411.1 0 8 0 0 1 Q03650 8.83e-72 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 28937 XM_044316411.1 0 8 0 0 1 Q03650 8.83e-72 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 28938 XM_044316411.1 0 8 0 0 1 Q03650 1.15e-71 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 28939 XM_044316411.1 0 8 0 0 1 Q03650 1.15e-71 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 28940 XM_044316411.1 0 8 0 0 1 Q03650 1.15e-71 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 28941 XM_044316411.1 0 8 0 0 1 Q03650 1.15e-71 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 28942 XM_044316411.1 0 8 0 0 1 Q03650 1.15e-71 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 28943 XM_044316411.1 0 8 0 0 1 Q03650 1.15e-71 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 28944 XM_044316411.1 0 8 0 0 1 Q03650 1.28e-71 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 28945 XM_044316411.1 0 8 0 0 1 Q03650 4.57e-71 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 28946 XM_044316411.1 0 8 0 0 1 Q03650 4.57e-71 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 28947 XM_044316411.1 0 8 0 0 1 Q03650 4.57e-71 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 28948 XM_044316411.1 0 8 0 0 1 Q03650 4.57e-71 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 28949 XM_044316411.1 0 8 0 0 1 Q03650 4.57e-71 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 28950 XM_044316411.1 0 8 0 0 1 Q03650 4.57e-71 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 28951 XM_044316411.1 0 8 0 0 1 Q03650 4.57e-71 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 28952 XM_044316411.1 0 8 0 0 1 Q03650 4.57e-71 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 28953 XM_044316411.1 0 8 0 0 1 Q03650 4.57e-71 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 28954 XM_044316411.1 0 8 0 0 1 Q03650 4.57e-71 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 28955 XM_044316411.1 0 8 0 0 1 Q03650 4.57e-71 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 28956 XM_044316411.1 0 8 0 0 1 Q03650 4.57e-71 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 28957 XM_044316411.1 0 8 0 0 1 Q03650 4.57e-71 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 28958 XM_044316411.1 0 8 0 0 1 Q03650 4.57e-71 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 28959 XM_044316411.1 0 8 0 0 1 Q03650 4.57e-71 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 28960 XM_044316411.1 0 8 0 0 1 Q03650 4.57e-71 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 28961 XM_044316411.1 0 8 0 0 1 Q03650 4.57e-71 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 28962 XM_044316411.1 0 8 0 0 1 Q03650 7.64e-71 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 28963 XM_044316411.1 0 8 0 0 1 Q03650 2.36e-70 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 28964 XM_044316411.1 0 8 0 0 1 Q03650 2.36e-70 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 28965 XM_044316411.1 0 8 0 0 1 Q03650 7.43e-70 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 28966 XM_044316411.1 0 8 0 0 1 Q03650 2.95e-69 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 28967 XM_044316411.1 0 8 0 0 1 Q03650 3.21e-21 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 28968 XM_029357283.2 997 517 333 1250 1651 A5PJX7 2.96e-108 Sodium- and chloride-dependent GABA transporter 2 (GAT-2) (Solute carrier family 6 member 13) Bos taurus (Bovine) amino acid import across plasma membrane [GO:0089718]; neurotransmitter transport [GO:0006836]; positive regulation of necrotic cell death [GO:0010940]; sodium ion transmembrane transport [GO:0035725] GO:0005332; GO:0005886; GO:0006836; GO:0010940; GO:0016323; GO:0035725; GO:0043005; GO:0089718 28969 XM_029329726.2 1048 2684 843 1172 1688 NA NA NA NA NA NA 28970 XM_029332541.2 0 12 34 17 22 NA NA NA NA NA NA 28971 XM_044328858.1 49 81 24 35 24 NA NA NA NA NA NA 28972 XM_044327742.1 16 0 25 20 0 NA NA NA NA NA NA 28973 XM_044315724.1 730 82 64 59 43 NA NA NA NA NA NA 28974 XM_044311848.1 56 15 25 71 10 P81274 4.69e-37 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 28975 XM_044311848.1 56 15 25 71 10 P81274 2.75e-34 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 28976 XM_044311848.1 56 15 25 71 10 P81274 2.23e-32 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 28977 XM_044311848.1 56 15 25 71 10 P81274 1.59e-29 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 28978 XM_029355340.2 952 55 185 201 220 Q6IWH7 0 Anoctamin-7 (Dresden transmembrane protein of the prostate) (D-TMPP) (IPCA-5) (New gene expressed in prostate) (Prostate cancer-associated protein 5) (Transmembrane protein 16G) Homo sapiens (Human) calcium activated phospholipid scrambling [GO:0061588]; chloride transmembrane transport [GO:1902476]; chloride transport [GO:0006821]; ion transmembrane transport [GO:0034220]; transmembrane transport [GO:0055085] GO:0005229; GO:0005254; GO:0005783; GO:0005829; GO:0005886; GO:0006821; GO:0034220; GO:0046983; GO:0055085; GO:0061588; GO:0070161; GO:1902476 28979 XM_029358444.2 179 94 55 192 33 Q6ZSM3 3.52e-24 Monocarboxylate transporter 12 (MCT 12) (Creatine transporter 2) (CRT2) (Solute carrier family 16 member 12) Homo sapiens (Human) creatine transmembrane transport [GO:0015881]; creatinine metabolic process [GO:0046449]; monocarboxylic acid transport [GO:0015718]; transport across blood-brain barrier [GO:0150104] GO:0005308; GO:0005886; GO:0008028; GO:0015292; GO:0015718; GO:0015881; GO:0016020; GO:0016323; GO:0046449; GO:0150104 28980 XM_029345119.2 0 12 0 0 30 Q9WTN0 1.12e-128 Geranylgeranyl pyrophosphate synthase (GGPP synthase) (GGPPSase) (EC 2.5.1.-) ((2E,6E)-farnesyl diphosphate synthase) (Dimethylallyltranstransferase) (EC 2.5.1.1) (Farnesyl diphosphate synthase) (Farnesyltranstransferase) (EC 2.5.1.29) (Geranylgeranyl diphosphate synthase) (Geranyltranstransferase) (EC 2.5.1.10) Mus musculus (Mouse) farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; geranylgeranyl diphosphate biosynthetic process [GO:0033386]; isoprenoid biosynthetic process [GO:0008299]; isoprenoid metabolic process [GO:0006720] GO:0004161; GO:0004311; GO:0004337; GO:0004659; GO:0005654; GO:0005737; GO:0005829; GO:0006720; GO:0008299; GO:0030018; GO:0033384; GO:0033386; GO:0042802; GO:0045337; GO:0046872; GO:0048471 28981 XM_029355703.2 0 0 0 0 100 NA NA NA NA NA NA 28982 XR_006397013.1 39 9 45 88 82 NA NA NA NA NA NA 28983 XM_044324815.1 513 475 351 370 320 Q9CPW7 1.48e-50 Zinc finger matrin-type protein 2 Mus musculus (Mouse) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0003677; GO:0005634; GO:0008270; GO:0046540; GO:0071005 28984 XM_044327436.1 110 54 68 130 47 NA NA NA NA NA NA 28985 XM_044309554.1 0 0 0 10 10 NA NA NA NA NA NA 28986 XM_029346707.2 2961 2637 2121 2754 3489 Q5PQS4 2.02e-49 PTB domain-containing engulfment adapter protein 1 (Cell death protein 6 homolog) (PTB domain adapter protein CED-6) (Protein GULP) Rattus norvegicus (Rat) apoptotic process [GO:0006915]; lipid transport [GO:0006869]; phagocytosis, engulfment [GO:0006911] GO:0005737; GO:0006869; GO:0006911; GO:0006915 28987 XM_029349727.2 779 693 560 917 832 Q99PT0 0 Probable ATP-dependent RNA helicase DDX52 (EC 3.6.4.13) (ATP-dependent RNA helicase ROK1-like) (rROK1L) (DEAD box protein 52) Rattus norvegicus (Rat) maturation of SSU-rRNA [GO:0030490]; rRNA processing [GO:0006364] GO:0003723; GO:0003724; GO:0005524; GO:0005730; GO:0006364; GO:0016887; GO:0030490 28988 XM_044323186.1 13 0 0 5 0 NA NA NA NA NA NA 28989 XM_029337363.2 432 198 224 646 825 Q61555 0 Fibrillin-2 [Cleaved into: Placensin] Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; limb morphogenesis [GO:0035108]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030326; GO:0030501; GO:0031012; GO:0035108; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 28990 XR_006393580.1 23 1 0 3 24 NA NA NA NA NA NA 28991 XM_044306774.1 0 0 0 7 21 NA NA NA NA NA NA 28992 XM_044315533.1 57 217 87 45 43 Q923S9 8.88e-56 Ras-related protein Rab-30 Mus musculus (Mouse) Golgi organization [GO:0007030]; Rab protein signal transduction [GO:0032482]; vesicle-mediated transport [GO:0016192] GO:0003924; GO:0005525; GO:0005801; GO:0005802; GO:0007030; GO:0016020; GO:0016192; GO:0031985; GO:0032482; GO:0043231 28993 XR_003824525.2 334 110 178 151 209 NA NA NA NA NA NA 28994 XM_044325640.1 169 38 98 27 106 Q91ZV3 5.01e-22 Discoidin, CUB and LCCL domain-containing protein 2 (Endothelial and smooth muscle cell-derived neuropilin-like protein) Mus musculus (Mouse) negative regulation of cell growth [GO:0030308]; wound healing [GO:0042060] GO:0005886; GO:0009986; GO:0030308; GO:0038023; GO:0042060 28995 XR_006393910.1 41 2 25 5 151 NA NA NA NA NA NA 28996 XM_044316162.1 5 0 7 1 1 NA NA NA NA NA NA 28997 XR_006397398.1 0 4 0 41 15 NA NA NA NA NA NA 28998 XM_044311699.1 1088 958 292 931 439 P51913 0 Alpha-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (Phosphopyruvate hydratase) Gallus gallus (Chicken) glycolytic process [GO:0006096] GO:0000015; GO:0000287; GO:0004634; GO:0005829; GO:0006096 28999 XM_029330563.2 353 118 233 426 428 O75899 2.91e-157 Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51) (HG20) Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway [GO:0007186]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; neuron-glial cell signaling [GO:0150099]; synaptic transmission, GABAergic [GO:0051932] GO:0004888; GO:0004965; GO:0005737; GO:0005886; GO:0007186; GO:0007193; GO:0007194; GO:0007214; GO:0007268; GO:0038039; GO:0043005; GO:0045211; GO:0046982; GO:0051932; GO:0150099; GO:1902710; GO:1902712 29000 XM_029358249.2 155 93 169 205 110 P17972 2.55e-105 Potassium voltage-gated channel protein Shaw (Shaw2) Drosophila melanogaster (Fruit fly) potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765]; sleep [GO:0030431] GO:0005249; GO:0005251; GO:0005886; GO:0006813; GO:0008076; GO:0016020; GO:0022843; GO:0030424; GO:0030431; GO:0032590; GO:0032809; GO:0034765; GO:0051260; GO:0071805 29001 XM_029339113.2 0 0 0 33 250 Q3TZ87 1.17e-22 E3 ubiquitin-protein ligase MARCHF9 (EC 2.3.2.27) (Membrane-associated RING finger protein 9) (Membrane-associated RING-CH protein IX) (MARCH-IX) (RING-type E3 ubiquitin transferase MARCHF9) Mus musculus (Mouse) NA GO:0000139; GO:0004842; GO:0005765; GO:0005795; GO:0005802; GO:0008270 29002 XM_029343769.2 120 32 38 47 23 NA NA NA NA NA NA 29003 XM_044307667.1 224 310 107 519 511 NA NA NA NA NA NA 29004 XM_029357534.2 191 391 167 182 208 A7SBF0 0 Integrator complex subunit 9 homolog Nematostella vectensis (Starlet sea anemone) snRNA 3'-end processing [GO:0034472] GO:0032039; GO:0034472 29005 XM_029336445.2 8 5 0 4 4 Q9I8C7 2.28e-99 Neuronal acetylcholine receptor subunit alpha-10 (Alpha 10 nAChR) (Nicotinic acetylcholine receptor subunit alpha-10) (NACHR alpha-10) Gallus gallus (Chicken) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; response to auditory stimulus [GO:0010996]; signal transduction [GO:0007165] GO:0004888; GO:0005231; GO:0005262; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0010996; GO:0022848; GO:0030594; GO:0034220; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051899; GO:1904315 29006 XM_044319901.1 339 323 163 185 334 Q5ZI16 3.08e-48 tRNA-specific adenosine deaminase 1 (EC 3.5.4.34) (tRNA-specific adenosine-37 deaminase) Gallus gallus (Chicken) tRNA processing [GO:0008033] GO:0003723; GO:0008033; GO:0008251; GO:0046872 29007 XM_029331227.2 45 14 27 57 35 A8I1Q0 2.1e-47 Calmodulin (CaM) Heterocapsa triquetra (Dinoflagellate) (Glenodinium triquetrum) NA GO:0005509 29008 XR_003826970.2 138 79 113 176 171 O15439 0 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 29009 XM_029343302.2 1209 1146 799 943 1015 NA NA NA NA NA NA 29010 XM_044327176.1 236 277 122 160 97 NA NA NA NA NA NA 29011 XM_029353281.2 33 0 0 100 0 Q8N9I5 3.92e-79 Fatty acid desaturase 6 (EC 1.14.19.-) Homo sapiens (Human) fatty acid biosynthetic process [GO:0006633]; lipid metabolic process [GO:0006629] GO:0006629; GO:0006633; GO:0016020; GO:0016717 29012 XM_029342113.2 11 49 10 0 21 NA NA NA NA NA NA 29013 XM_029345998.2 0 0 0 0 119 P53804 1.13e-41 E3 ubiquitin-protein ligase TTC3 (EC 2.3.2.27) (Protein DCRR1) (RING finger protein 105) (RING-type E3 ubiquitin transferase TTC3) (TPR repeat protein D) (Tetratricopeptide repeat protein 3) (TPR repeat protein 3) Homo sapiens (Human) protein K48-linked ubiquitination [GO:0070936]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004842; GO:0005634; GO:0005654; GO:0005730; GO:0005794; GO:0005829; GO:0006511; GO:0046872; GO:0070936 29014 XM_029344358.2 16 2 4 20 5 NA NA NA NA NA NA 29015 XM_044307610.1 478 383 266 140 299 Q5NVD0 0 U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0005681; GO:0006397; GO:0008380; GO:0016607; GO:0071001; GO:0097525 29016 XM_029346206.2 1 0 7 0 7 P30549 3.66e-29 Substance-K receptor (SKR) (NK-2 receptor) (NK-2R) (Neurokinin A receptor) (Tachykinin receptor 2) Mus musculus (Mouse) intestine smooth muscle contraction [GO:0014827]; negative regulation of luteinizing hormone secretion [GO:0033685]; operant conditioning [GO:0035106]; positive regulation of acetylcholine secretion, neurotransmission [GO:0014057]; positive regulation of flagellated sperm motility [GO:1902093]; positive regulation of ion transport [GO:0043270]; positive regulation of uterine smooth muscle contraction [GO:0070474]; positive regulation of vascular permeability [GO:0043117]; prolactin secretion [GO:0070459]; regulation of uterine smooth muscle contraction [GO:0070472]; response to electrical stimulus [GO:0051602] GO:0004995; GO:0005886; GO:0014057; GO:0014827; GO:0016020; GO:0016497; GO:0033685; GO:0035106; GO:0036126; GO:0043117; GO:0043270; GO:0051602; GO:0061827; GO:0070459; GO:0070472; GO:0070474; GO:0097225; GO:1902093 29017 XM_044328686.1 117 0 0 0 261 P16065 0 Speract receptor (EC 4.6.1.2) (Guanylate cyclase) Strongylocentrotus purpuratus (Purple sea urchin) cGMP biosynthetic process [GO:0006182]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]; receptor guanylyl cyclase signaling pathway [GO:0007168]; signal transduction [GO:0007165] GO:0001653; GO:0004383; GO:0004672; GO:0005524; GO:0005525; GO:0005886; GO:0006182; GO:0006468; GO:0007165; GO:0007168; GO:0035556 29018 XM_044309570.1 9 12 6 28 197 NA NA NA NA NA NA 29019 XM_029343272.2 816 602 602 1097 1287 Q8TC84 6.08e-78 Fibronectin type 3 and ankyrin repeat domains protein 1 Homo sapiens (Human) negative regulation of apoptotic process [GO:0043066]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of apoptotic process [GO:0042981] GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005929; GO:0036064; GO:0042981; GO:0043065; GO:0043066; GO:0045893; GO:0051091; GO:0097546 29020 XM_029329675.2 1041 1607 888 1007 1073 Q925U4 0 ER degradation-enhancing alpha-mannosidase-like protein 1 Mus musculus (Mouse) carbohydrate metabolic process [GO:0005975]; endoplasmic reticulum mannose trimming [GO:1904380]; mannose trimming involved in glycoprotein ERAD pathway [GO:1904382]; positive regulation of retrograde protein transport, ER to cytosol [GO:1904154]; protein targeting to ER [GO:0045047]; response to unfolded protein [GO:0006986]; trimming of terminal mannose on C branch [GO:0036510]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent glycoprotein ERAD pathway [GO:0097466] GO:0004571; GO:0005509; GO:0005783; GO:0005789; GO:0005975; GO:0006986; GO:0016235; GO:0030433; GO:0036510; GO:0044322; GO:0045047; GO:0051787; GO:0097466; GO:1904154; GO:1904380; GO:1904382 29021 XM_044315896.1 27 26 31 63 21 NA NA NA NA NA NA 29022 XM_044321500.1 41 103 38 148 92 Q9U3S9 8.4e-53 Zinc metalloproteinase nas-6 (EC 3.4.24.-) (Nematode astacin 6) Caenorhabditis elegans pharyngeal pumping [GO:0043050]; pharynx development [GO:0060465]; proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0006508; GO:0008270; GO:0043050; GO:0060465 29023 XM_044324531.1 41 78 116 52 107 NA NA NA NA NA NA 29024 XM_029355362.2 736 519 378 669 601 Q58CP2 1.41e-111 Inactive C-alpha-formylglycine-generating enzyme 2 (Sulfatase-modifying factor 2) Bos taurus (Bovine) NA GO:0005783; GO:0005788; GO:0046872 29025 XM_044308457.1 1 305 97 101 16 NA NA NA NA NA NA 29026 XM_029326551.2 6 7 11 12 41 NA NA NA NA NA NA 29027 XM_029337628.2 101 16 0 91 13 NA NA NA NA NA NA 29028 XM_029337209.2 1669 1056 746 1606 1335 U3JAG9 3.04e-159 Centrosomal protein of 131 kDa (5-azacytidine-induced protein 1) Danio rerio (Zebrafish) (Brachydanio rerio) cell differentiation [GO:0030154]; cilium assembly [GO:0060271]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; intraciliary retrograde transport [GO:0035721]; intraciliary transport involved in cilium assembly [GO:0035735]; Kupffer's vesicle development [GO:0070121]; melanosome transport [GO:0032402]; negative regulation of intracellular protein transport [GO:0090317]; regulation of centrosome duplication [GO:0010824]; sensory perception of light stimulus [GO:0050953] GO:0000775; GO:0001669; GO:0005576; GO:0005929; GO:0010824; GO:0030154; GO:0032402; GO:0034451; GO:0035721; GO:0035735; GO:0050953; GO:0060271; GO:0060287; GO:0070121; GO:0090317 29029 XM_044327928.1 0 1 17 0 1 NA NA NA NA NA NA 29030 XM_044311100.1 38 0 30 159 68 Q3UQ28 7.56e-33 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 29031 XM_044311100.1 38 0 30 159 68 Q3UQ28 1.61e-26 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 29032 XM_044311134.1 25 4 11 52 62 Q3UQ28 3.13e-30 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 29033 XM_044311134.1 25 4 11 52 62 Q3UQ28 5.72e-29 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 29034 XM_029324397.2 9 3 0 5 4 NA NA NA NA NA NA 29035 XM_044312683.1 69 62 11 0 123 NA NA NA NA NA NA 29036 XM_029349233.2 75 6 35 13 12 NA NA NA NA NA NA 29037 XM_029335253.2 797 722 305 417 244 NA NA NA NA NA NA 29038 XM_029354252.2 35 10 5 39 87 Q9UGM3 5.92e-57 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 29039 XM_029354252.2 35 10 5 39 87 Q9UGM3 1.88e-55 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 29040 XM_029354252.2 35 10 5 39 87 Q9UGM3 9.64e-55 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 29041 XM_029354252.2 35 10 5 39 87 Q9UGM3 1.21e-54 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 29042 XM_029354252.2 35 10 5 39 87 Q9UGM3 1.79e-54 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 29043 XM_029354252.2 35 10 5 39 87 Q9UGM3 2.81e-54 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 29044 XM_029354252.2 35 10 5 39 87 Q9UGM3 5.4e-54 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 29045 XM_029354252.2 35 10 5 39 87 Q9UGM3 2.26e-52 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 29046 XM_029354252.2 35 10 5 39 87 Q9UGM3 4.58e-52 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 29047 XM_029354252.2 35 10 5 39 87 Q9UGM3 1.29e-51 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 29048 XM_029354252.2 35 10 5 39 87 Q9UGM3 1.04e-29 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 29049 XM_029354252.2 35 10 5 39 87 Q9UGM3 1.29e-25 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 29050 XM_029343509.2 0 0 17 26 10 NA NA NA NA NA NA 29051 XM_029328667.2 627 381 99 979 202 NA NA NA NA NA NA 29052 XM_029323467.2 723 529 424 465 539 Q9UBU9 3.3e-140 Nuclear RNA export factor 1 (Tip-associated protein) (Tip-associating protein) (mRNA export factor TAP) Homo sapiens (Human) mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; protein transport [GO:0015031] GO:0003723; GO:0003729; GO:0005634; GO:0005643; GO:0005654; GO:0005737; GO:0005829; GO:0006406; GO:0010494; GO:0015031; GO:0016607; GO:0016973; GO:0042272; GO:0042405 29053 XM_044322337.1 0 136 0 0 0 NA NA NA NA NA NA 29054 XM_044311988.1 0 0 0 6 0 NA NA NA NA NA NA 29055 XR_006394566.1 32 26 7 0 166 NA NA NA NA NA NA 29056 XM_029358328.2 630 685 407 479 654 P20749 8.88e-44 B-cell lymphoma 3 protein (BCL-3) (Proto-oncogene BCL3) Homo sapiens (Human) antimicrobial humoral response [GO:0019730]; cellular response to DNA damage stimulus [GO:0006974]; defense response to bacterium [GO:0042742]; defense response to protozoan [GO:0042832]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; extracellular matrix organization [GO:0030198]; follicular dendritic cell differentiation [GO:0002268]; germinal center formation [GO:0002467]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; marginal zone B cell differentiation [GO:0002315]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of T cell apoptotic process [GO:0070233]; negative regulation of tumor necrosis factor production [GO:0032720]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translation [GO:0045727]; positive regulation of type II interferon production [GO:0032729]; protein import into nucleus [GO:0006606]; regulation of apoptotic process [GO:0042981]; regulation of DNA binding [GO:0051101]; regulation of NIK/NF-kappaB signaling [GO:1901222]; response to UV-C [GO:0010225]; response to virus [GO:0009615]; spleen development [GO:0048536]; T cell apoptotic process [GO:0070231]; T-helper 1 type immune response [GO:0042088]; T-helper 2 cell differentiation [GO:0045064] GO:0002268; GO:0002315; GO:0002455; GO:0002467; GO:0003713; GO:0003714; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0006606; GO:0006974; GO:0007249; GO:0009615; GO:0010225; GO:0019730; GO:0030198; GO:0030330; GO:0030496; GO:0030674; GO:0032088; GO:0032717; GO:0032720; GO:0032729; GO:0032733; GO:0032991; GO:0032996; GO:0033257; GO:0042088; GO:0042742; GO:0042771; GO:0042826; GO:0042832; GO:0042981; GO:0043066; GO:0043231; GO:0045064; GO:0045727; GO:0045892; GO:0045893; GO:0045944; GO:0046426; GO:0048471; GO:0048536; GO:0051101; GO:0070231; GO:0070233; GO:0140297; GO:1901222 29057 XM_029348839.2 491 199 0 1416 142 Q9FWW9 2.97e-72 Flavin-containing monooxygenase FMO GS-OX-like 2 (EC 1.8.-.-) (Flavin-monooxygenase glucosinolate S-oxygenase-like 2) Arabidopsis thaliana (Mouse-ear cress) defense response to fungus [GO:0050832] GO:0004499; GO:0050660; GO:0050661; GO:0050832 29058 XM_029329496.2 971 1429 964 1784 1484 P09057 3.28e-158 Ornithine decarboxylase (ODC) (EC 4.1.1.17) Rattus norvegicus (Rat) cell population proliferation [GO:0008283]; kidney development [GO:0001822]; polyamine metabolic process [GO:0006595]; positive regulation of cell population proliferation [GO:0008284]; putrescine biosynthetic process [GO:0009446]; putrescine biosynthetic process from ornithine [GO:0033387]; regulation of protein catabolic process [GO:0042176]; response to virus [GO:0009615] GO:0001822; GO:0004586; GO:0005737; GO:0005829; GO:0006595; GO:0008283; GO:0008284; GO:0009446; GO:0009615; GO:0033387; GO:0042176; GO:0042803; GO:0048471 29059 XM_029342261.2 0 4 347 1459 255 O00712 8.04e-97 Nuclear factor 1 B-type (NF1-B) (Nuclear factor 1/B) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/B) (NF-I/B) (NFI-B) (TGGCA-binding protein) Homo sapiens (Human) anterior commissure morphogenesis [GO:0021960]; brain development [GO:0007420]; cell differentiation involved in salivary gland development [GO:0060689]; chondrocyte differentiation [GO:0002062]; club cell differentiation [GO:0060486]; commissural neuron axon guidance [GO:0071679]; DNA replication [GO:0006260]; glandular epithelial cell differentiation [GO:0002067]; glial cell differentiation [GO:0010001]; hindbrain development [GO:0030902]; lung ciliated cell differentiation [GO:0061141]; negative regulation of DNA binding [GO:0043392]; negative regulation of epithelial cell proliferation involved in lung morphogenesis [GO:2000795]; negative regulation of mesenchymal cell proliferation involved in lung development [GO:2000791]; negative regulation of miRNA transcription [GO:1902894]; negative regulation of stem cell proliferation [GO:2000647]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; principal sensory nucleus of trigeminal nerve development [GO:0021740]; regulation of transcription by RNA polymerase II [GO:0006357]; response to bacterium [GO:0009617]; salivary gland cavitation [GO:0060662]; stem cell proliferation [GO:0072089]; type I pneumocyte differentiation [GO:0060509]; type II pneumocyte differentiation [GO:0060510] GO:0000122; GO:0000785; GO:0000978; GO:0000981; GO:0001228; GO:0001650; GO:0002062; GO:0002067; GO:0003677; GO:0005634; GO:0005654; GO:0006260; GO:0006357; GO:0007420; GO:0009617; GO:0010001; GO:0021740; GO:0021960; GO:0030902; GO:0043392; GO:0044300; GO:0045893; GO:0045944; GO:0060486; GO:0060509; GO:0060510; GO:0060662; GO:0060689; GO:0061141; GO:0071679; GO:0072089; GO:0140416; GO:1902894; GO:1990837; GO:2000647; GO:2000791; GO:2000795 29060 XM_029342136.2 393 294 244 539 244 NA NA NA NA NA NA 29061 XM_029337806.2 58 0 0 0 0 Q09299 2.96e-43 Putative RNA-binding protein EEED8.10 Caenorhabditis elegans SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0003723; GO:0019005; GO:0031146 29062 XM_029345388.2 2636 3509 1590 2283 2069 A4QNF3 5.71e-27 Reactive oxygen species modulator 1 (ROS modulator 1) (Protein MGR2 homolog) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cellular response to reactive oxygen species [GO:0034614]; defense response to bacterium [GO:0042742]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; replicative senescence [GO:0090399] GO:0005739; GO:0005743; GO:0008284; GO:0034614; GO:0042742; GO:0090399; GO:2000379 29063 XM_044314085.1 169 34 51 80 0 NA NA NA NA NA NA 29064 XM_044312947.1 5 6 8 9 0 NA NA NA NA NA NA 29065 XM_044312880.1 0 84 16 58 67 Q5NCR9 4.52e-36 Nuclear speckle splicing regulatory protein 1 (Coiled-coil domain-containing protein 55) (Nuclear speckle-related protein 70) (NSrp70) Mus musculus (Mouse) developmental process [GO:0032502]; in utero embryonic development [GO:0001701]; mRNA processing [GO:0006397]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380] GO:0000381; GO:0001701; GO:0003729; GO:0005634; GO:0005654; GO:0006397; GO:0008380; GO:0016607; GO:0032502; GO:1990904 29066 XM_044312525.1 6 17 9 6 55 NA NA NA NA NA NA 29067 XR_006397010.1 55 12 2 8 40 NA NA NA NA NA NA 29068 XM_029329100.2 810 328 145 354 0 Q96242 5.36e-29 Allene oxide synthase, chloroplastic (EC 4.2.1.92) (Cytochrome P450 74A) (Hydroperoxide dehydrase) Arabidopsis thaliana (Mouse-ear cress) defense response [GO:0006952]; defense response to fungus [GO:0050832]; epoxygenase P450 pathway [GO:0019373]; fatty acid biosynthetic process [GO:0006633]; jasmonic acid biosynthetic process [GO:0009695]; oxylipin biosynthetic process [GO:0031408]; oxylipin metabolic process [GO:0031407]; response to fungus [GO:0009620]; response to jasmonic acid [GO:0009753]; response to wounding [GO:0009611]; sterol metabolic process [GO:0016125] GO:0004497; GO:0005506; GO:0005739; GO:0006633; GO:0006952; GO:0009507; GO:0009534; GO:0009535; GO:0009536; GO:0009579; GO:0009611; GO:0009620; GO:0009695; GO:0009753; GO:0009941; GO:0009978; GO:0010287; GO:0016125; GO:0016491; GO:0016705; GO:0019373; GO:0019825; GO:0020037; GO:0031407; GO:0031408; GO:0050832 29069 XM_029329802.2 57 0 7 0 11 NA NA NA NA NA NA 29070 XM_044328888.1 18 35 0 54 32 Q7TN88 2.41e-62 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 29071 XM_044328888.1 18 35 0 54 32 Q7TN88 1.56e-49 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 29072 XM_029323540.2 20 17 14 31 25 P25100 6.38e-29 Alpha-1D adrenergic receptor (Alpha-1A adrenergic receptor) (Alpha-1D adrenoreceptor) (Alpha-1D adrenoceptor) (Alpha-adrenergic receptor 1a) Homo sapiens (Human) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell-cell signaling [GO:0007267]; G protein-coupled receptor signaling pathway [GO:0007186]; neuron-glial cell signaling [GO:0150099]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of vasoconstriction [GO:0045907] GO:0001996; GO:0004930; GO:0004937; GO:0005886; GO:0007186; GO:0007188; GO:0007200; GO:0007204; GO:0007267; GO:0008284; GO:0042802; GO:0043410; GO:0045907; GO:0071880; GO:0150099 29073 XM_044311092.1 44 0 8 7 30 NA NA NA NA NA NA 29074 XM_029325315.2 453 417 190 321 538 Q9R088 4.67e-55 Thymidine kinase 2, mitochondrial (EC 2.7.1.21) (2'-deoxyuridine kinase TK2) (EC 2.7.1.74) (Deoxycytidine kinase TK2) (EC 2.7.1.-) (Mt-TK) Mus musculus (Mouse) deoxycytidine metabolic process [GO:0046092]; deoxyribonucleotide metabolic process [GO:0009262]; DNA biosynthetic process [GO:0071897]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA replication [GO:0006264]; phosphorylation [GO:0016310]; thymidine metabolic process [GO:0046104] GO:0004137; GO:0004797; GO:0005524; GO:0005737; GO:0005739; GO:0005743; GO:0006264; GO:0009262; GO:0016310; GO:0019136; GO:0032042; GO:0046092; GO:0046104; GO:0071897 29075 XM_044319171.1 256 62 0 284 88 O88917 5.94e-49 Adhesion G protein-coupled receptor L1 (Calcium-independent alpha-latrotoxin receptor 1) (CIRL-1) (Latrophilin-1) Rattus norvegicus (Rat) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; brain development [GO:0007420]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell surface receptor signaling pathway [GO:0007166]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synapse maturation [GO:0090129] GO:0004930; GO:0005886; GO:0007157; GO:0007166; GO:0007189; GO:0007420; GO:0014069; GO:0015643; GO:0016524; GO:0030246; GO:0030424; GO:0030426; GO:0035584; GO:0042734; GO:0043005; GO:0045202; GO:0050839; GO:0051965; GO:0090129; GO:0098978 29076 XM_029331999.2 42 0 126 0 106 NA NA NA NA NA NA 29077 XM_029345488.2 2733 2344 1862 3602 2972 Q00534 3.09e-119 Cyclin-dependent kinase 6 (EC 2.7.11.22) (Cell division protein kinase 6) (Serine/threonine-protein kinase PLSTIRE) Homo sapiens (Human) astrocyte development [GO:0014002]; cell dedifferentiation [GO:0043697]; cell division [GO:0051301]; dentate gyrus development [GO:0021542]; G1/S transition of mitotic cell cycle [GO:0000082]; generation of neurons [GO:0048699]; gliogenesis [GO:0042063]; hematopoietic stem cell differentiation [GO:0060218]; lateral ventricle development [GO:0021670]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cellular senescence [GO:2000773]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]; regulation of cell cycle [GO:0051726]; regulation of cell motility [GO:2000145]; regulation of erythrocyte differentiation [GO:0045646]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; response to virus [GO:0009615]; T cell differentiation in thymus [GO:0033077]; type B pancreatic cell development [GO:0003323] GO:0000082; GO:0000122; GO:0000307; GO:0001726; GO:0001954; GO:0003323; GO:0004693; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0005829; GO:0006468; GO:0007219; GO:0008285; GO:0009615; GO:0010468; GO:0010628; GO:0014002; GO:0016592; GO:0021542; GO:0021670; GO:0030332; GO:0033077; GO:0042063; GO:0043697; GO:0045596; GO:0045638; GO:0045646; GO:0045656; GO:0045668; GO:0045786; GO:0048146; GO:0048699; GO:0050680; GO:0051301; GO:0051726; GO:0060218; GO:0097132; GO:0098770; GO:0106310; GO:1902036; GO:2000145; GO:2000773 29078 XM_029354404.2 12 12 1 18 32 NA NA NA NA NA NA 29079 XR_003825911.2 67 24 73 44 76 NA NA NA NA NA NA 29080 XM_044315583.1 31 7 23 38 84 NA NA NA NA NA NA 29081 XM_029351445.2 10 0 14 7 101 B8VIU6 1.03e-49 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 29082 XM_029324095.2 3697 1921 1121 2639 1953 Q5M7N9 4.05e-84 Extended synaptotagmin-3 (E-Syt3) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) endoplasmic reticulum-plasma membrane tethering [GO:0061817]; lipid transport [GO:0006869] GO:0005789; GO:0005886; GO:0006869; GO:0008289; GO:0046872; GO:0061817; GO:0140268 29083 XR_006391480.1 45 32 42 28 61 NA NA NA NA NA NA 29084 XM_044317006.1 1658 1378 780 1252 1701 Q5ZIN1 3.12e-90 Nuclear migration protein nudC (Nuclear distribution protein C homolog) Gallus gallus (Chicken) cell division [GO:0051301]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle organization [GO:0007052]; protein folding [GO:0006457] GO:0005737; GO:0005874; GO:0006457; GO:0007052; GO:0007080; GO:0030496; GO:0051082; GO:0051301; GO:0072686 29085 XM_044328250.1 23201 21793 20109 25425 24915 Q8MPM1 2.26e-110 Gelsolin-like protein 2 (Actin-modulator) (EWAM-P2) Lumbricus terrestris (Common earthworm) actin filament capping [GO:0051693] GO:0005737; GO:0005856; GO:0051015; GO:0051693 29086 XM_044327558.1 170 45 126 85 182 NA NA NA NA NA NA 29087 XM_044321535.1 0 130 0 15 0 NA NA NA NA NA NA 29088 XM_044318948.1 668 650 354 434 651 Q641G4 2.76e-104 Condensin-2 complex subunit H2 (Non-SMC condensin II complex subunit H2) Xenopus laevis (African clawed frog) chromosome condensation [GO:0030261] GO:0005634; GO:0030261 29089 XM_044319832.1 579 373 113 345 50 Q6YP21 9.29e-155 Kynurenine--oxoglutarate transaminase 3 (EC 2.6.1.7) (Cysteine-S-conjugate beta-lyase 2) (EC 4.4.1.13) (Kynurenine aminotransferase 3) (Kynurenine aminotransferase III) (KATIII) (Kynurenine--glyoxylate transaminase) (EC 2.6.1.63) (Kynurenine--oxoglutarate transaminase III) Homo sapiens (Human) 2-oxoglutarate metabolic process [GO:0006103]; amino acid metabolic process [GO:0006520]; biosynthetic process [GO:0009058]; kynurenine metabolic process [GO:0070189]; L-kynurenine catabolic process [GO:0097053] GO:0003723; GO:0005737; GO:0005739; GO:0006103; GO:0006520; GO:0009058; GO:0016212; GO:0030170; GO:0042803; GO:0047315; GO:0047804; GO:0070189; GO:0097053 29090 XM_029336113.2 337 349 172 290 122 O15155 1.56e-27 BET1 homolog (hBET1) (Golgi vesicular membrane-trafficking protein p18) Homo sapiens (Human) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; protein transport [GO:0015031]; vesicle fusion with Golgi apparatus [GO:0048280] GO:0000138; GO:0000139; GO:0005484; GO:0005789; GO:0006888; GO:0015031; GO:0016020; GO:0030133; GO:0031201; GO:0033116; GO:0048280 29091 XR_006394627.1 108 211 97 132 101 A0A2B4SJA1 4.41e-69 NA NA NA NA 29092 XM_044314467.1 0 0 0 0 11 NA NA NA NA NA NA 29093 XM_029335417.2 34 0 0 5 21 F4NUJ6 5.31e-124 tRNA (guanine(37)-N1)-methyltransferase (EC 2.1.1.228) (M1G-methyltransferase) (tRNA [GM37] methyltransferase) (tRNA methyltransferase 5) Batrachochytrium dendrobatidis (strain JAM81 / FGSC 10211) (Frog chytrid fungus) mitochondrial tRNA methylation [GO:0070901]; tRNA methylation [GO:0030488]; tRNA N1-guanine methylation [GO:0002939] GO:0002939; GO:0005634; GO:0005737; GO:0005759; GO:0008175; GO:0009019; GO:0030488; GO:0052906; GO:0070901 29094 XM_044319798.1 0 96 0 0 0 NA NA NA NA NA NA 29095 XM_044324109.1 45 17 14 37 19 E9Q5R7 4.16e-30 NACHT, LRR and PYD domains-containing protein 12 (Monarch-1) (PYRIN-containing APAF1-like protein 7) (PYPAF7) Mus musculus (Mouse) cellular response to cytokine stimulus [GO:0071345]; dendritic cell migration [GO:0036336]; ERK1 and ERK2 cascade [GO:0070371]; negative regulation of cytokine production [GO:0001818]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of signal transduction [GO:0009968]; negative regulation of Toll signaling pathway [GO:0045751]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of inflammatory response [GO:0050727] GO:0001818; GO:0005524; GO:0005737; GO:0009968; GO:0031953; GO:0032088; GO:0032692; GO:0032715; GO:0036336; GO:0038061; GO:0043122; GO:0043124; GO:0043281; GO:0045345; GO:0045751; GO:0050727; GO:0050728; GO:0070371; GO:0070373; GO:0071345; GO:1901223; GO:1901224 29096 XM_029356682.2 0 0 22 0 0 P56517 0 Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-) Gallus gallus (Chicken) chromatin organization [GO:0006325]; circadian regulation of gene expression [GO:0032922]; DNA methylation-dependent heterochromatin formation [GO:0006346]; embryonic digit morphogenesis [GO:0042733]; endoderm development [GO:0007492]; epidermal cell differentiation [GO:0009913]; eyelid development in camera-type eye [GO:0061029]; fungiform papilla formation [GO:0061198]; hippocampus development [GO:0021766]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endopeptidase activity [GO:0052548]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000118; GO:0000122; GO:0000792; GO:0000979; GO:0001222; GO:0002039; GO:0003714; GO:0004407; GO:0005634; GO:0005737; GO:0005829; GO:0006325; GO:0006346; GO:0006357; GO:0007492; GO:0008284; GO:0009913; GO:0016580; GO:0016581; GO:0017053; GO:0021766; GO:0030182; GO:0032922; GO:0035851; GO:0042733; GO:0042826; GO:0043025; GO:0043124; GO:0043922; GO:0045944; GO:0047485; GO:0048709; GO:0048714; GO:0051059; GO:0052548; GO:0060766; GO:0061029; GO:0061198; GO:0070888; GO:0070932; GO:0070933; GO:0090090; GO:0140297; GO:0160009; GO:1990841; GO:2000273; GO:2001243 29097 XM_044313557.1 263 318 154 274 238 Q8TD10 1.01e-47 Mirror-image polydactyly gene 1 protein Homo sapiens (Human) NA GO:0005634; GO:0042802 29098 XM_044317100.1 5197 3638 2331 5604 3319 NA NA NA NA NA NA 29099 XM_044310195.1 12 23 0 70 32 NA NA NA NA NA NA 29100 XM_044308307.1 128 61 82 150 231 Q13309 2.36e-50 S-phase kinase-associated protein 2 (Cyclin-A/CDK2-associated protein p45) (F-box protein Skp2) (F-box/LRR-repeat protein 1) (p45skp2) Homo sapiens (Human) defense response to virus [GO:0051607]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; innate immune response [GO:0045087]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of protein polyubiquitination [GO:1902916]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K48-linked ubiquitination [GO:0070936]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0000082; GO:0000086; GO:0005634; GO:0005654; GO:0005730; GO:0005829; GO:0019005; GO:0031146; GO:0033148; GO:0042802; GO:0042981; GO:0043161; GO:0045087; GO:0051607; GO:0051726; GO:0070936; GO:1902916 29101 XM_044319787.1 403 124 22 631 132 Q8R151 2.02e-131 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 29102 XM_044319787.1 403 124 22 631 132 Q8R151 2.02e-79 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 29103 XM_044319787.1 403 124 22 631 132 Q8R151 7.33e-72 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 29104 XM_044319787.1 403 124 22 631 132 Q8R151 9.28e-23 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 29105 XM_044310181.1 0 2 0 0 6 NA NA NA NA NA NA 29106 XM_029338232.2 564 310 749 713 644 NA NA NA NA NA NA 29107 XM_044317135.1 725 1432 720 949 1686 NA NA NA NA NA NA 29108 XM_044309138.1 253 17 0 105 0 NA NA NA NA NA NA 29109 XM_044323680.1 2 0 27 0 24 P71359 7.49e-38 ATP-dependent DNA helicase RecQ (EC 3.6.4.12) Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; SOS response [GO:0009432] GO:0003677; GO:0005524; GO:0005694; GO:0005737; GO:0006260; GO:0006281; GO:0006310; GO:0009378; GO:0009432; GO:0016887; GO:0030894; GO:0032508; GO:0043138; GO:0043590 29110 XM_029334815.2 6 0 0 0 52 NA NA NA NA NA NA 29111 XM_044320698.1 19 13 1 0 2 O02751 2.42e-23 Craniofacial development protein 2 (p97 bucentaur protein) Bos taurus (Bovine) chromatin remodeling [GO:0006338] GO:0003824; GO:0005634; GO:0005737; GO:0006338 29112 XM_044323598.1 639 734 736 1263 1304 B3EWZ9 0 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 29113 XM_029345228.2 5129 4125 2636 4112 3414 P13701 1.39e-31 Synaptobrevin (Synaptic vesicle-associated integral membrane protein) (VAMP-1) Tetronarce californica (Pacific electric ray) (Torpedo californica) vesicle-mediated transport [GO:0016192] GO:0016192; GO:0030672; GO:0043005 29114 XM_044309634.1 642 1017 338 122 89 NA NA NA NA NA NA 29115 XM_044313211.1 159 78 81 83 214 Q3YSJ8 2.36e-158 DNA mismatch repair protein MutS Ehrlichia canis (strain Jake) mismatch repair [GO:0006298] GO:0003684; GO:0005524; GO:0006298; GO:0030983; GO:0140664 29116 XM_044324253.1 0 15 82 127 75 Q6AYM1 6.38e-29 Uncharacterized protein C5orf34 homolog Rattus norvegicus (Rat) NA NA 29117 XM_044322245.1 736 348 328 450 573 Q92834 1.81e-93 X-linked retinitis pigmentosa GTPase regulator Homo sapiens (Human) cilium assembly [GO:0060271]; intracellular protein transport [GO:0006886]; intraciliary transport [GO:0042073]; response to stimulus [GO:0050896]; visual perception [GO:0007601] GO:0001750; GO:0003723; GO:0005085; GO:0005737; GO:0005794; GO:0005813; GO:0005929; GO:0006886; GO:0007601; GO:0036064; GO:0036126; GO:0042073; GO:0050896; GO:0060271 29118 XM_044323875.1 0 0 4 7 0 NA NA NA NA NA NA 29119 XM_044314833.1 5 8 2 17 7 NA NA NA NA NA NA 29120 XM_029336970.2 36 22 154 88 126 P51869 5.49e-106 Cytochrome P450 4F4 (CYPIVF4) (Leukotriene-B4 20-monooxygenase) (EC 1.14.14.94) Rattus norvegicus (Rat) arachidonic acid metabolic process [GO:0019369]; leukotriene B4 catabolic process [GO:0036101]; menaquinone catabolic process [GO:0042361]; omega-hydroxylase P450 pathway [GO:0097267]; phylloquinone catabolic process [GO:0042376]; prostaglandin catabolic process [GO:1905344] GO:0005506; GO:0005789; GO:0008391; GO:0019369; GO:0020037; GO:0036101; GO:0042361; GO:0042376; GO:0043231; GO:0050051; GO:0097267; GO:1905344 29121 XM_029342455.2 2184 855 859 874 1114 Q6INX4 0 Mitochondrial enolase superfamily member 1 (L-fuconate dehydratase) (EC 4.2.1.68) Xenopus laevis (African clawed frog) cellular carbohydrate catabolic process [GO:0044275] GO:0000287; GO:0005739; GO:0016853; GO:0044275; GO:0050023 29122 XM_044311920.1 24 85 62 8 255 NA NA NA NA NA NA 29123 XM_029354239.2 6 14 0 0 33 NA NA NA NA NA NA 29124 XM_029340183.2 127 302 153 77 68 A8DZE6 6.23e-59 Wilms tumor protein 1-interacting protein homolog (WT1-interacting protein homolog) Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; cloaca development [GO:0035844]; cytoskeleton organization [GO:0007010]; determination of heart left/right asymmetry [GO:0061371]; determination of left/right asymmetry in lateral mesoderm [GO:0003140]; establishment of mitotic spindle orientation [GO:0000132]; heart looping [GO:0001947]; negative regulation of hippo signaling [GO:0035331]; neural crest cell development [GO:0014032]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; regulation of cell morphogenesis [GO:0022604]; regulation of DNA-templated transcription [GO:0006355]; response to hypoxia [GO:0001666]; visceral serous pericardium development [GO:0061032] GO:0000132; GO:0000932; GO:0001666; GO:0001947; GO:0003140; GO:0003714; GO:0005634; GO:0005667; GO:0005912; GO:0006355; GO:0007010; GO:0014032; GO:0022604; GO:0035331; GO:0035844; GO:0036064; GO:0046872; GO:0060271; GO:0061032; GO:0061371; GO:2000637 29125 XM_029329574.2 0 0 16 26 0 A4IGL7 2.93e-89 Peroxidasin (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0005576; GO:0005604; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0031012; GO:0042744; GO:0046872; GO:0051260; GO:0070207; GO:0070831; GO:0071711; GO:0140825 29126 XM_029351113.2 851 664 797 682 1041 Q2T9Y1 3.9e-45 Uncharacterized protein C3orf26 homolog Bos taurus (Bovine) NA NA 29127 XM_044321477.1 24 40 28 42 50 NA NA NA NA NA NA 29128 XM_029336979.2 818 212 426 853 744 Q6PAY6 1.02e-89 Hydroxyproline dehydrogenase (HYPDH) (EC 1.5.5.3) (Probable proline dehydrogenase 2) (EC 1.5.5.2) (Probable proline oxidase 2) Xenopus laevis (African clawed frog) proline catabolic process to glutamate [GO:0010133] GO:0004657; GO:0010133; GO:0016645 29129 XM_029337419.2 672 0 0 293 542 NA NA NA NA NA NA 29130 XM_044306864.1 20 50 5 1607 918 B3EWY9 0 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 29131 XM_044324413.1 1 0 0 125 4 P10079 0 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 29132 XM_044324413.1 1 0 0 125 4 P10079 0 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 29133 XM_044324413.1 1 0 0 125 4 P10079 0 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 29134 XM_044324413.1 1 0 0 125 4 P10079 0 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 29135 XM_044324413.1 1 0 0 125 4 P10079 0 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 29136 XM_029343231.2 484 374 269 0 96 Q8BIE6 5.13e-133 FERM domain-containing protein 4A Mus musculus (Mouse) establishment of epithelial cell polarity [GO:0090162]; negative regulation of protein secretion [GO:0050709]; positive regulation of protein secretion [GO:0050714] GO:0005737; GO:0005856; GO:0005912; GO:0005923; GO:0030674; GO:0050709; GO:0050714; GO:0090162 29137 XM_044312073.1 49 197 228 177 799 R1CW23 3.66e-100 Dimethylsulfonioproprionate lyase 7 (DMSP lyase 7) (EC 4.4.1.3) (Dimethylpropiothetin dethiomethylase 7) Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi) NA GO:0047869 29138 XR_006395739.1 0 49 0 0 33 NA NA NA NA NA NA 29139 XM_029338605.2 1667 2664 1005 1716 1248 NA NA NA NA NA NA 29140 XM_044308847.1 45 13 102 952 323 O16025 1.37e-40 Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (AOS) (EC 4.2.1.-) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)] Plexaura homomalla (Black sea rod) arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; lipid oxidation [GO:0034440]; oxylipin biosynthetic process [GO:0031408] GO:0005506; GO:0005737; GO:0006633; GO:0009978; GO:0016020; GO:0019369; GO:0020037; GO:0031408; GO:0034440; GO:0047677 29141 XM_044323802.1 100 22 56 45 90 NA NA NA NA NA NA 29142 XM_029356938.2 1567 905 733 968 1257 Q96I25 9.48e-59 Splicing factor 45 (45 kDa-splicing factor) (RNA-binding motif protein 17) Homo sapiens (Human) alternative mRNA splicing, via spliceosome [GO:0000380]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398] GO:0000380; GO:0000398; GO:0003723; GO:0005654; GO:0005681; GO:0045292 29143 XM_029340199.2 2009 2113 1152 1671 2266 Q0III3 0 Cytoplasmic dynein 1 intermediate chain 2 (Cytoplasmic dynein intermediate chain 2) (Dynein intermediate chain 2, cytosolic) (DH IC-2) Bos taurus (Bovine) microtubule-based movement [GO:0007018]; transport along microtubule [GO:0010970] GO:0005737; GO:0005868; GO:0005874; GO:0007018; GO:0010970; GO:0031982; GO:0045503; GO:0045504 29144 XM_029344306.2 223 188 170 348 545 O75417 0 DNA polymerase theta (EC 2.7.7.7) (DNA polymerase eta) Homo sapiens (Human) base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-templated DNA replication [GO:0006261]; double-strand break repair [GO:0006302]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; protein homooligomerization [GO:0051260]; somatic hypermutation of immunoglobulin genes [GO:0016446] GO:0003682; GO:0003684; GO:0003887; GO:0005524; GO:0005654; GO:0005694; GO:0005794; GO:0005829; GO:0006261; GO:0006281; GO:0006284; GO:0006302; GO:0006974; GO:0016446; GO:0017116; GO:0042802; GO:0051260; GO:0051575; GO:0097681; GO:2000042 29145 XM_029344306.2 223 188 170 348 545 O75417 0 DNA polymerase theta (EC 2.7.7.7) (DNA polymerase eta) Homo sapiens (Human) base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-templated DNA replication [GO:0006261]; double-strand break repair [GO:0006302]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; protein homooligomerization [GO:0051260]; somatic hypermutation of immunoglobulin genes [GO:0016446] GO:0003682; GO:0003684; GO:0003887; GO:0005524; GO:0005654; GO:0005694; GO:0005794; GO:0005829; GO:0006261; GO:0006281; GO:0006284; GO:0006302; GO:0006974; GO:0016446; GO:0017116; GO:0042802; GO:0051260; GO:0051575; GO:0097681; GO:2000042 29146 XM_044316134.1 8 95 35 0 76 NA NA NA NA NA NA 29147 XM_044319980.1 0 0 0 0 9 Q3UMR0 0 Ankyrin repeat domain-containing protein 27 (VPS9 domain-containing protein) (VPS9-ankyrin-repeat protein) Mus musculus (Mouse) early endosome to late endosome transport [GO:0045022]; endocytic recycling [GO:0032456]; endosome to melanosome transport [GO:0035646]; negative regulation of SNARE complex assembly [GO:0035544]; neuron projection morphogenesis [GO:0048812]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of neuron projection development [GO:0010976]; protein transport [GO:0015031] GO:0000149; GO:0005085; GO:0005096; GO:0005764; GO:0005769; GO:0005770; GO:0005829; GO:0005886; GO:0010976; GO:0015031; GO:0030133; GO:0030659; GO:0031267; GO:0032456; GO:0035544; GO:0035646; GO:0042470; GO:0043005; GO:0043231; GO:0045022; GO:0048812; GO:0050775; GO:0097422 29148 XR_006395521.1 0 0 0 0 236 NA NA NA NA NA NA 29149 XM_029344424.2 20 2 29 19 16 Q8VCH8 3.05e-74 UBX domain-containing protein 4 (Erasin) (UBX domain-containing protein 2) Mus musculus (Mouse) response to unfolded protein [GO:0006986]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0005635; GO:0005783; GO:0005789; GO:0005829; GO:0006986; GO:0030433 29150 XM_044311713.1 5 15 0 25 43 B8VIU6 8.74e-43 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 29151 XR_006393463.1 8 0 0 0 7 NA NA NA NA NA NA 29152 XR_006391444.1 235 159 68 118 183 NA NA NA NA NA NA 29153 XM_029348717.2 202 166 151 383 337 Q2KHM9 2.8e-22 Protein moonraker (MNR) (OFD1- and FOPNL-interacting protein) Homo sapiens (Human) centriole replication [GO:0007099]; cilium assembly [GO:0060271]; cytosolic ciliogenesis [GO:0061824]; protein localization to centrosome [GO:0071539] GO:0005813; GO:0005814; GO:0005829; GO:0007099; GO:0034451; GO:0046872; GO:0051537; GO:0060271; GO:0061824; GO:0071539 29154 XR_006395774.1 1 5 10 9 12 NA NA NA NA NA NA 29155 XM_029350851.2 330 51 35 222 40 NA NA NA NA NA NA 29156 XR_006395206.1 4 0 33 64 37 NA NA NA NA NA NA 29157 XM_044325770.1 50 27 15 85 84 P10079 3.91e-87 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 29158 XM_044325770.1 50 27 15 85 84 P10079 5.52e-83 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 29159 XM_044325770.1 50 27 15 85 84 P10079 1.88e-49 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 29160 XM_044325770.1 50 27 15 85 84 P10079 2.2e-46 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 29161 XM_044325770.1 50 27 15 85 84 P10079 5.94e-46 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 29162 XM_044325770.1 50 27 15 85 84 P10079 3.12e-45 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 29163 XM_044325770.1 50 27 15 85 84 P10079 8.53e-43 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 29164 XM_044325770.1 50 27 15 85 84 P10079 2.13e-41 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 29165 XM_044325770.1 50 27 15 85 84 P10079 1.46e-40 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 29166 XM_044325770.1 50 27 15 85 84 P10079 5.66e-40 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 29167 XM_044325770.1 50 27 15 85 84 P10079 2.91e-39 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 29168 XM_044325770.1 50 27 15 85 84 P10079 1.72e-37 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 29169 XM_044325770.1 50 27 15 85 84 P10079 3.15e-33 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 29170 XR_006393767.1 1 20 82 5 9 NA NA NA NA NA NA 29171 XM_044315416.1 0 0 0 833 0 NA NA NA NA NA NA 29172 XM_029338768.2 1073 4281 4019 928 1665 B3EWZ5 4.21e-113 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 29173 XM_029338768.2 1073 4281 4019 928 1665 B3EWZ5 1.06e-111 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 29174 XM_029338768.2 1073 4281 4019 928 1665 B3EWZ5 4.04e-108 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 29175 XM_029338768.2 1073 4281 4019 928 1665 B3EWZ5 3.45e-107 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 29176 XM_029338768.2 1073 4281 4019 928 1665 B3EWZ5 3.6e-96 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 29177 XM_029338768.2 1073 4281 4019 928 1665 B3EWZ5 1.08e-92 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 29178 XM_029338768.2 1073 4281 4019 928 1665 B3EWZ5 3.91e-89 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 29179 XM_029338768.2 1073 4281 4019 928 1665 B3EWZ5 1.9e-80 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 29180 XM_029338768.2 1073 4281 4019 928 1665 B3EWZ5 1.26e-77 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 29181 XM_029338768.2 1073 4281 4019 928 1665 B3EWZ5 2.21e-68 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 29182 XM_029338768.2 1073 4281 4019 928 1665 B3EWZ5 3.91e-63 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 29183 XM_029338768.2 1073 4281 4019 928 1665 B3EWZ5 2.07e-50 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 29184 XM_029338768.2 1073 4281 4019 928 1665 B3EWZ5 6.13e-50 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 29185 XM_029338768.2 1073 4281 4019 928 1665 B3EWZ5 3.4e-46 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 29186 XM_029338768.2 1073 4281 4019 928 1665 B3EWZ5 2.27e-40 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 29187 XM_029338768.2 1073 4281 4019 928 1665 B3EWZ5 9.01e-37 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 29188 XM_029338768.2 1073 4281 4019 928 1665 B3EWZ5 1.67e-35 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 29189 XM_029338768.2 1073 4281 4019 928 1665 B3EWZ5 5.78e-29 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 29190 XM_029338768.2 1073 4281 4019 928 1665 B3EWZ5 2.4e-26 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 29191 XM_029338768.2 1073 4281 4019 928 1665 B3EWZ5 1.8e-25 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 29192 XR_006393171.1 0 0 0 0 18 Q8K4Q6 1.95e-96 Endonuclease 8-like 1 (EC 3.2.2.-) (EC 4.2.99.18) (DNA glycosylase/AP lyase Neil1) (DNA-(apurinic or apyrimidinic site) lyase Neil1) (Endonuclease VIII-like 1) (Nei homolog 1) (NEH1) (Nei-like protein 1) Mus musculus (Mouse) base-excision repair [GO:0006284]; DNA repair [GO:0006281]; negative regulation of nuclease activity [GO:0032074]; response to oxidative stress [GO:0006979] GO:0003684; GO:0003906; GO:0005634; GO:0005654; GO:0005694; GO:0005737; GO:0005815; GO:0006281; GO:0006284; GO:0006979; GO:0008022; GO:0008270; GO:0016798; GO:0016829; GO:0019104; GO:0032074; GO:0140078 29193 XM_044314863.1 1 0 30 0 52 NA NA NA NA NA NA 29194 XM_029326922.2 3 7 15 12 45 NA NA NA NA NA NA 29195 XM_044320674.1 48 17 1 49 37 NA NA NA NA NA NA 29196 XM_044323362.1 3265 2993 2162 2174 3079 O75431 9.41e-60 Metaxin-2 (Mitochondrial outer membrane import complex protein 2) Homo sapiens (Human) inner mitochondrial membrane organization [GO:0007007]; mitochondrial transport [GO:0006839]; mitochondrion organization [GO:0007005]; protein insertion into mitochondrial outer membrane [GO:0045040] GO:0001401; GO:0005730; GO:0005737; GO:0005739; GO:0005741; GO:0006839; GO:0007005; GO:0007007; GO:0045040; GO:0140275 29197 XR_006391856.1 164 272 15 26 17 NA NA NA NA NA NA 29198 XM_029328961.2 0 85 0 254 74 O88696 1.87e-106 ATP-dependent Clp protease proteolytic subunit, mitochondrial (EC 3.4.21.92) (Endopeptidase Clp) Mus musculus (Mouse) membrane protein proteolysis [GO:0033619]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603] GO:0004175; GO:0004176; GO:0004252; GO:0005739; GO:0005759; GO:0006508; GO:0006515; GO:0009368; GO:0033619; GO:0042802; GO:0051117; GO:0051603 29199 XM_029342352.2 84 0 68 135 50 P98156 2.33e-157 Very low-density lipoprotein receptor (VLDL receptor) (VLDL-R) Mus musculus (Mouse) cellular response to hypoxia [GO:0071456]; cholesterol metabolic process [GO:0008203]; dendrite morphogenesis [GO:0048813]; glycoprotein transport [GO:0034436]; lipid transport [GO:0006869]; positive regulation of dendrite development [GO:1900006]; positive regulation of protein kinase activity [GO:0045860]; receptor-mediated endocytosis [GO:0006898]; reelin-mediated signaling pathway [GO:0038026]; ventral spinal cord development [GO:0021517]; very-low-density lipoprotein particle clearance [GO:0034447] GO:0005509; GO:0005615; GO:0005634; GO:0005886; GO:0005905; GO:0006869; GO:0006898; GO:0008203; GO:0009986; GO:0016020; GO:0021517; GO:0030229; GO:0034185; GO:0034189; GO:0034361; GO:0034436; GO:0034447; GO:0038024; GO:0038025; GO:0038026; GO:0043235; GO:0045177; GO:0045860; GO:0048306; GO:0048471; GO:0048813; GO:0071456; GO:1900006 29200 XM_029329117.2 75 84 61 35 313 Q29RM1 9.81e-87 Mitochondrial thiamine pyrophosphate carrier (Solute carrier family 25 member 19) Bos taurus (Bovine) thiamine pyrophosphate transmembrane transport [GO:0030974] GO:0005739; GO:0005743; GO:0015234; GO:0015297; GO:0030974; GO:0090422 29201 XM_029352957.2 772 789 646 696 776 Q28H76 1.17e-100 tRNA (guanine-N(7)-)-methyltransferase A (EC 2.1.1.33) (Methyltransferase-like protein 1-A) (mRNA (guanine-N(7)-)-methyltransferase) (EC 2.1.1.-) (miRNA (guanine-N(7)-)-methyltransferase) (EC 2.1.1.-) (tRNA (guanine(46)-N(7))-methyltransferase A) (tRNA(m7G46)-methyltransferase A) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) tRNA modification [GO:0006400] GO:0000049; GO:0005634; GO:0006400; GO:0008176 29202 XM_029339406.2 432 272 276 192 426 NA NA NA NA NA NA 29203 XM_044320608.1 6 16 21 19 54 NA NA NA NA NA NA 29204 XR_003826175.2 9 0 0 0 2 NA NA NA NA NA NA 29205 XM_029347517.2 6638 5502 4309 5866 3568 Q6AY20 1.48e-34 Cation-dependent mannose-6-phosphate receptor (CD Man-6-P receptor) (CD-MPR) Rattus norvegicus (Rat) lysosomal transport [GO:0007041]; protein targeting to lysosome [GO:0006622]; secretion of lysosomal enzymes [GO:0033299] GO:0005765; GO:0005768; GO:0005770; GO:0005802; GO:0006622; GO:0007041; GO:0019904; GO:0033299; GO:0048471; GO:1905394 29206 XR_006393508.1 17 46 87 30 53 NA NA NA NA NA NA 29207 XR_006397190.1 0 0 0 39 1 NA NA NA NA NA NA 29208 XM_044325117.1 106 41 58 49 102 NA NA NA NA NA NA 29209 XM_044317652.1 274 120 150 241 382 Q5XHG1 8.84e-116 Sphingomyelin phosphodiesterase 4 (EC 3.1.4.12) (Neutral sphingomyelinase 3) (nSMase-3) (nSMase3) (Neutral sphingomyelinase III) Xenopus laevis (African clawed frog) cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; sphingomyelin catabolic process [GO:0006685] GO:0000139; GO:0004767; GO:0005635; GO:0005783; GO:0005789; GO:0006685; GO:0042383; GO:0046513; GO:0046872; GO:0050290; GO:0071356 29210 XM_029344319.2 367 97 348 412 181 P33731 7.78e-167 Signal recognition particle subunit SRP72 (SRP72) (Signal recognition particle 72 kDa protein) Canis lupus familiaris (Dog) (Canis familiaris) SRP-dependent cotranslational protein targeting to membrane [GO:0006614] GO:0005047; GO:0005783; GO:0005786; GO:0005829; GO:0006614; GO:0008312; GO:0030911; GO:0043022 29211 XM_029330001.2 0 0 20 62 0 Q9TTT5 3.71e-90 Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3) Oryctolagus cuniculus (Rabbit) protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0008076; GO:0030425; GO:0034765; GO:0042383; GO:0046872; GO:0051260 29212 XM_044321488.1 0 0 619 0 0 Q01804 2.16e-71 OTU domain-containing protein 4 (EC 3.4.19.12) (HIV-1-induced protein HIN-1) Homo sapiens (Human) innate immune response [GO:0045087]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; positive regulation of DNA demethylation [GO:1901537]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; regulation of protein K48-linked deubiquitination [GO:1903093] GO:0003723; GO:0004843; GO:0005634; GO:0005829; GO:0016579; GO:0034122; GO:0045087; GO:0060090; GO:0061578; GO:0070536; GO:0071108; GO:1901537; GO:1903093; GO:2000660 29213 XM_029344764.2 1181 858 143 553 561 P35668 6.39e-119 Glutathione synthetase (GSH synthetase) (GSH-S) (EC 6.3.2.3) (Glutathione synthase) Xenopus laevis (African clawed frog) NA GO:0000287; GO:0004363; GO:0005524; GO:0042803; GO:0043295 29214 XR_006395108.1 702 408 6 433 119 NA NA NA NA NA NA 29215 XM_044320786.1 1243 989 929 1078 1885 NA NA NA NA NA NA 29216 XM_029336577.2 235 45 0 133 110 Q66KD6 9.55e-53 Probable phosphatase phospho2 (EC 3.1.3.-) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0016791; GO:0046872 29217 XM_029337961.2 62 37 0 108 0 NA NA NA NA NA NA 29218 XM_029331394.2 87 6 73 56 293 NA NA NA NA NA NA 29219 XM_029332457.2 35 55 41 93 37 NA NA NA NA NA NA 29220 XM_029341543.2 111 126 104 190 144 NA NA NA NA NA NA 29221 XM_044329153.1 0 7 0 15 15 P31579 1.65e-21 Low choriolytic enzyme (EC 3.4.24.66) (Choriolysin L) (Hatching enzyme zinc-protease subunit LCE) Oryzias latipes (Japanese rice fish) (Japanese killifish) proteolysis [GO:0006508] GO:0004222; GO:0006508; GO:0008270; GO:0042588 29222 XM_044324255.1 656 0 136 432 584 A2AJ76 1.14e-52 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 29223 XM_044324255.1 656 0 136 432 584 A2AJ76 5.52e-50 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 29224 XM_044324255.1 656 0 136 432 584 A2AJ76 1.83e-48 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 29225 XM_044324255.1 656 0 136 432 584 A2AJ76 1.43e-46 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 29226 XM_044324255.1 656 0 136 432 584 A2AJ76 1.56e-43 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 29227 XM_044324255.1 656 0 136 432 584 A2AJ76 1.82e-40 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 29228 XM_044324255.1 656 0 136 432 584 A2AJ76 3.29e-38 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 29229 XM_044324255.1 656 0 136 432 584 A2AJ76 3.41e-38 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 29230 XM_044324255.1 656 0 136 432 584 A2AJ76 3.83e-38 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 29231 XM_044324255.1 656 0 136 432 584 A2AJ76 5.69e-38 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 29232 XM_044324255.1 656 0 136 432 584 A2AJ76 3.62e-37 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 29233 XM_044324255.1 656 0 136 432 584 A2AJ76 4.65e-37 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 29234 XM_044324255.1 656 0 136 432 584 A2AJ76 1.13e-35 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 29235 XM_044324255.1 656 0 136 432 584 A2AJ76 1.47e-35 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 29236 XM_044324255.1 656 0 136 432 584 A2AJ76 1.83e-35 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 29237 XM_044324255.1 656 0 136 432 584 A2AJ76 6.41e-35 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 29238 XM_044324255.1 656 0 136 432 584 A2AJ76 4.04e-34 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 29239 XM_044324255.1 656 0 136 432 584 A2AJ76 9.77e-32 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 29240 XM_044324255.1 656 0 136 432 584 A2AJ76 2.26e-30 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 29241 XM_044324255.1 656 0 136 432 584 A2AJ76 4.36e-28 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 29242 XM_029323627.2 1468 4260 3041 1892 1492 NA NA NA NA NA NA 29243 XM_044317940.1 9 0 0 35 18 Q6AZB8 5.25e-50 Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0004518; GO:0005634; GO:0005737; GO:0046872 29244 XM_029348831.2 576 558 328 455 527 NA NA NA NA NA NA 29245 XM_044317434.1 0 0 5 6 0 NA NA NA NA NA NA 29246 XM_044326319.1 0 0 1 0 12 NA NA NA NA NA NA 29247 XM_029340318.2 6102 8526 4220 7639 7664 Q13322 2.69e-65 Growth factor receptor-bound protein 10 (GRB10 adapter protein) (Insulin receptor-binding protein Grb-IR) Homo sapiens (Human) ERK1 and ERK2 cascade [GO:0070371]; gene expression [GO:0010467]; insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009]; negative regulation of glucose import [GO:0046325]; negative regulation of glycogen biosynthetic process [GO:0045719]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of phosphorylation [GO:0042326]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of phosphorylation [GO:0042327]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; response to insulin [GO:0032868]; vascular associated smooth muscle cell migration [GO:1904738] GO:0005158; GO:0005737; GO:0005829; GO:0005886; GO:0008286; GO:0010467; GO:0030159; GO:0030178; GO:0030949; GO:0032868; GO:0032991; GO:0042326; GO:0042327; GO:0042802; GO:0045719; GO:0046325; GO:0046627; GO:0048009; GO:0070371; GO:0120162; GO:1904738 29248 XM_029349936.2 5 4 5 6 8 P12276 0 Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Acyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)] Gallus gallus (Chicken) fatty acid biosynthetic process [GO:0006633]; lactate metabolic process [GO:0006089]; positive regulation of appetite [GO:0032100] GO:0003697; GO:0004312; GO:0004313; GO:0004314; GO:0004315; GO:0004316; GO:0004317; GO:0004320; GO:0005737; GO:0006089; GO:0006633; GO:0008659; GO:0008693; GO:0016295; GO:0016296; GO:0031177; GO:0032100; GO:0047117; GO:0047451 29249 XM_029349936.2 5 4 5 6 8 P12276 0 Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Acyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)] Gallus gallus (Chicken) fatty acid biosynthetic process [GO:0006633]; lactate metabolic process [GO:0006089]; positive regulation of appetite [GO:0032100] GO:0003697; GO:0004312; GO:0004313; GO:0004314; GO:0004315; GO:0004316; GO:0004317; GO:0004320; GO:0005737; GO:0006089; GO:0006633; GO:0008659; GO:0008693; GO:0016295; GO:0016296; GO:0031177; GO:0032100; GO:0047117; GO:0047451 29250 XM_044323387.1 55 8 0 0 0 Q9JM13 1.37e-76 Rab5 GDP/GTP exchange factor (Rabex-5) Mus musculus (Mouse) dendritic transport [GO:0098935]; establishment of localization in cell [GO:0051649]; Kit signaling pathway [GO:0038109]; mast cell degranulation [GO:0043303]; mast cell migration [GO:0097531]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of Kit signaling pathway [GO:1900235]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of mast cell activation [GO:0033004]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; negative regulation of receptor-mediated endocytosis [GO:0048261]; protein phosphorylation [GO:0006468]; protein targeting to membrane [GO:0006612]; Ras protein signal transduction [GO:0007265]; receptor-mediated endocytosis [GO:0006898]; regulation of Fc receptor mediated stimulatory signaling pathway [GO:0060368] GO:0001933; GO:0002686; GO:0003677; GO:0005085; GO:0005730; GO:0005769; GO:0005829; GO:0006468; GO:0006612; GO:0006898; GO:0007265; GO:0008270; GO:0030139; GO:0030425; GO:0031267; GO:0031982; GO:0032715; GO:0032764; GO:0033004; GO:0038109; GO:0043303; GO:0043305; GO:0046580; GO:0048261; GO:0050728; GO:0051649; GO:0055037; GO:0060368; GO:0061630; GO:0097531; GO:0098935; GO:1900235 29251 XM_044311561.1 0 0 0 0 14 NA NA NA NA NA NA 29252 XM_029350829.2 552 190 411 246 306 Q1PRL4 5.55e-29 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Gallus gallus (Chicken) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 29253 XM_029358379.2 4297 4592 3617 3907 3492 Q8BQB6 2.99e-30 Stabilizer of axonemal microtubules 2 Mus musculus (Mouse) NA GO:0005634; GO:0005814; GO:0005856; GO:0005879; GO:0008017; GO:0036064; GO:0036126 29254 XM_044308017.1 45 43 27 114 73 NA NA NA NA NA NA 29255 XM_044324673.1 269 190 128 232 151 Q8C8R3 3.84e-21 Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) Mus musculus (Mouse) atrial cardiac muscle cell action potential [GO:0086014]; atrial cardiac muscle cell to AV node cell communication [GO:0086066]; atrial septum development [GO:0003283]; cardiac muscle contraction [GO:0060048]; cellular calcium ion homeostasis [GO:0006874]; endocytosis [GO:0006897]; positive regulation of calcium ion transmembrane transporter activity [GO:1901021]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cation channel activity [GO:2001259]; positive regulation of gene expression [GO:0010628]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to endoplasmic reticulum [GO:0070972]; protein localization to M-band [GO:0036309]; protein localization to organelle [GO:0033365]; protein localization to plasma membrane [GO:0072659]; protein localization to T-tubule [GO:0036371]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; regulation of atrial cardiac muscle cell action potential [GO:0098910]; regulation of AV node cell action potential [GO:0098904]; regulation of calcium ion transmembrane transporter activity [GO:1901019]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cardiac muscle cell membrane potential [GO:0086036]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cation channel activity [GO:2001257]; regulation of heart rate [GO:0002027]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of protein stability [GO:0031647]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of SA node cell action potential [GO:0098907]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; SA node cell action potential [GO:0086015]; SA node cell to atrial cardiac muscle cell communication [GO:0086070]; T-tubule organization [GO:0033292]; ventricular cardiac muscle cell action potential [GO:0086005] GO:0002027; GO:0003283; GO:0005200; GO:0005737; GO:0005739; GO:0005764; GO:0005769; GO:0005856; GO:0005886; GO:0006874; GO:0006897; GO:0008104; GO:0010628; GO:0010881; GO:0010882; GO:0014069; GO:0014704; GO:0015031; GO:0015459; GO:0016323; GO:0019899; GO:0019901; GO:0030018; GO:0030315; GO:0030507; GO:0030674; GO:0031234; GO:0031430; GO:0031647; GO:0031672; GO:0033010; GO:0033292; GO:0033365; GO:0034394; GO:0036309; GO:0036371; GO:0042383; GO:0043005; GO:0043034; GO:0043268; GO:0044325; GO:0045121; GO:0045211; GO:0048471; GO:0050821; GO:0051117; GO:0051279; GO:0051924; GO:0051928; GO:0055037; GO:0055117; GO:0060048; GO:0060307; GO:0070972; GO:0072659; GO:0086004; GO:0086005; GO:0086014; GO:0086015; GO:0086036; GO:0086066; GO:0086070; GO:0086091; GO:0098904; GO:0098907; GO:0098910; GO:0140031; GO:1901018; GO:1901019; GO:1901021; GO:2001257; GO:2001259 29256 XR_006393281.1 30 0 0 0 0 NA NA NA NA NA NA 29257 XM_029350933.2 79 62 57 94 128 Q02040 5.16e-107 A-kinase anchor protein 17A (AKAP-17A) (721P) (B-lymphocyte antigen) (Protein XE7) (Protein kinase A-anchoring protein 17A) (PRKA17A) (Splicing factor, arginine/serine-rich 17A) Homo sapiens (Human) B cell activation [GO:0042113]; mRNA processing [GO:0006397]; regulation of DNA-templated transcription [GO:0006355]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]; signal transduction [GO:0007165] GO:0003723; GO:0005634; GO:0005681; GO:0005829; GO:0006355; GO:0006397; GO:0007165; GO:0008380; GO:0016607; GO:0042113; GO:0043484; GO:0051018 29258 XR_006397143.1 15 6 14 26 71 NA NA NA NA NA NA 29259 XM_044307476.1 7 0 0 0 12 Q09575 9.57e-21 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 29260 XM_044307476.1 7 0 0 0 12 Q09575 9.57e-21 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 29261 XM_044322014.1 2660 2419 279 2417 257 P20072 1.29e-130 Annexin A7 (Annexin VII) (Annexin-7) (Synexin) Bos taurus (Bovine) NA GO:0005509; GO:0005544; GO:0005634; GO:0005737; GO:0042584 29262 XR_006396912.1 1 0 9 132 21 NA NA NA NA NA NA 29263 XM_029327226.2 101 29 52 55 16 Q5FWS6 4.94e-84 Kazrin Rattus norvegicus (Rat) keratinization [GO:0031424] GO:0001533; GO:0005829; GO:0005856; GO:0016607; GO:0030057; GO:0031424 29264 XM_029327226.2 101 29 52 55 16 Q5FWS6 2.2e-24 Kazrin Rattus norvegicus (Rat) keratinization [GO:0031424] GO:0001533; GO:0005829; GO:0005856; GO:0016607; GO:0030057; GO:0031424 29265 XM_044321053.1 0 0 4 0 6 NA NA NA NA NA NA 29266 XM_044327622.1 63 115 26 17 20 NA NA NA NA NA NA 29267 XR_003825264.2 8 33 10 0 2 NA NA NA NA NA NA 29268 XM_044323367.1 116 83 27 47 23 Q15119 6.3e-96 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 2) (PDH kinase 2) (PDKII) Homo sapiens (Human) cellular response to nutrient [GO:0031670]; cellular response to reactive oxygen species [GO:0034614]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; insulin receptor signaling pathway [GO:0008286]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; protein phosphorylation [GO:0006468]; regulation of acetyl-CoA biosynthetic process from pyruvate [GO:0010510]; regulation of calcium-mediated signaling [GO:0050848]; regulation of cellular ketone metabolic process [GO:0010565]; regulation of gluconeogenesis [GO:0006111]; regulation of glucose metabolic process [GO:0010906]; regulation of pH [GO:0006885] GO:0004672; GO:0004740; GO:0005524; GO:0005654; GO:0005739; GO:0005759; GO:0005829; GO:0005967; GO:0006006; GO:0006111; GO:0006468; GO:0006885; GO:0008286; GO:0010510; GO:0010565; GO:0010906; GO:0031670; GO:0034614; GO:0042593; GO:0042803; GO:0050848; GO:0072332 29269 XM_029328618.2 1799 1555 1042 1698 1864 Q5PQY6 0 Lon protease homolog 2, peroxisomal (EC 3.4.21.53) Danio rerio (Zebrafish) (Brachydanio rerio) protein import into peroxisome matrix [GO:0016558]; protein processing [GO:0016485]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; protein targeting to peroxisome [GO:0006625] GO:0004176; GO:0004252; GO:0005524; GO:0005782; GO:0006515; GO:0006625; GO:0016485; GO:0016558; GO:0016887 29270 XM_029351653.2 417 456 401 556 449 P54948 9.33e-38 Uncharacterized protein YxeI Bacillus subtilis (strain 168) NA GO:0016787 29271 XM_029344183.2 5737 4118 4652 5560 4559 Q39056 1.13e-51 Cyclic pyranopterin monophosphate synthase, mitochondrial (EC 4.6.1.17) (Molybdenum cofactor biosynthesis enzyme CNX3) (Molybdenum cofactor biosynthesis protein C) (Molybdopterin biosynthesis protein CNX3) Arabidopsis thaliana (Mouse-ear cress) Mo-molybdopterin cofactor biosynthetic process [GO:0006777] GO:0005739; GO:0005759; GO:0006777; GO:0009507; GO:0061799 29272 XM_044312292.1 385 7 31 22 17 NA NA NA NA NA NA 29273 XM_029330200.2 896 755 465 1158 389 P22125 8.7e-91 Ras-related protein ORAB-1 Diplobatis ommata (Ocellated electric ray) (Discopyge ommata) protein transport [GO:0015031] GO:0003924; GO:0005525; GO:0005886; GO:0015031 29274 XM_044328222.1 322 47 46 73 91 NA NA NA NA NA NA 29275 XM_029350703.2 591 481 355 507 386 NA NA NA NA NA NA 29276 XR_006392894.1 41 2 25 5 151 NA NA NA NA NA NA 29277 XM_029330743.2 877 403 342 555 989 Q91820 2.67e-150 Aurora kinase A-A (EC 2.7.11.1) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (Serine/threonine-protein kinase 6-A) (Serine/threonine-protein kinase Eg2-A) (pEg2) (Serine/threonine-protein kinase aurora-A) (p46Eg265) Xenopus laevis (African clawed frog) cell division [GO:0051301]; meiotic spindle organization [GO:0000212]; mitotic centrosome separation [GO:0007100]; mitotic spindle assembly [GO:0090307]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777] GO:0000212; GO:0000922; GO:0004674; GO:0005524; GO:0005737; GO:0005813; GO:0005876; GO:0007100; GO:0008017; GO:0018105; GO:0019894; GO:0046777; GO:0051301; GO:0090307; GO:0106310 29278 XM_044311994.1 147 39 57 22 57 C3VPR6 4.32e-27 Protein NLRC5 Mus musculus (Mouse) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of type II interferon-mediated signaling pathway [GO:0060335]; regulation of kinase activity [GO:0043549]; response to bacterium [GO:0009617] GO:0000978; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0009617; GO:0032088; GO:0035556; GO:0043549; GO:0045087; GO:0045345; GO:0045944; GO:0051607; GO:0060335; GO:0060339; GO:0060340 29279 XM_044321968.1 318 220 159 255 218 O75486 2.09e-68 Transcription initiation protein SPT3 homolog (SPT3-like protein) Homo sapiens (Human) histone acetylation [GO:0016573]; histone H3 acetylation [GO:0043966]; monoubiquitinated histone deubiquitination [GO:0035521]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA repair [GO:0006282]; regulation of DNA-templated transcription [GO:0006355]; regulation of RNA splicing [GO:0043484]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366] GO:0000124; GO:0003713; GO:0005634; GO:0005654; GO:0006282; GO:0006355; GO:0006357; GO:0006366; GO:0016573; GO:0033276; GO:0035521; GO:0035522; GO:0043484; GO:0043966; GO:0045893; GO:0046982 29280 XM_029348164.2 503 126 213 553 604 Q8NBP0 0 Tetratricopeptide repeat protein 13 (TPR repeat protein 13) Homo sapiens (Human) NA NA 29281 XR_006397302.1 0 0 4 24 10 NA NA NA NA NA NA 29282 XM_044327869.1 19 0 22 6 36 NA NA NA NA NA NA 29283 XM_029334863.2 564 304 272 216 402 Q8IV38 8.65e-120 Ankyrin repeat and MYND domain-containing protein 2 Homo sapiens (Human) NA GO:0005929; GO:0019899; GO:0046872 29284 XR_006394181.1 15 0 0 7 0 NA NA NA NA NA NA 29285 XM_029339724.2 1026 664 402 1362 1341 NA NA NA NA NA NA 29286 XM_044328977.1 12 0 36 33 48 Q4R550 3.99e-67 Cysteine--tRNA ligase, cytoplasmic (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) cysteinyl-tRNA aminoacylation [GO:0006423] GO:0000049; GO:0004817; GO:0005524; GO:0005737; GO:0006423; GO:0046872 29287 XR_006395732.1 133 56 4 89 106 NA NA NA NA NA NA 29288 XM_029323518.2 126 146 102 94 77 Q5TZ07 1.04e-32 Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6 (EC 3.1.3.-) (EC 3.6.1.-) (EC 3.6.1.68) (Phosphatidic acid phosphatase type 2 domain-containing protein 2) (Phospholipid phosphatase 6) Danio rerio (Zebrafish) (Brachydanio rerio) farnesyl diphosphate catabolic process [GO:0045339]; geranyl diphosphate metabolic process [GO:0033383]; geranylgeranyl diphosphate catabolic process [GO:1902247]; phospholipid dephosphorylation [GO:0046839]; protein prenylation [GO:0018342] GO:0005637; GO:0005789; GO:0016020; GO:0018342; GO:0031965; GO:0033383; GO:0042392; GO:0045339; GO:0046839; GO:1902247 29289 XM_029325251.2 530 703 435 787 1135 Q5R3I4 4.69e-139 Tetratricopeptide repeat protein 38 (TPR repeat protein 38) Homo sapiens (Human) NA GO:0070062 29290 XM_029347879.2 2280 1168 1106 2055 1780 Q86TI0 9.89e-117 TBC1 domain family member 1 Homo sapiens (Human) activation of GTPase activity [GO:0090630] GO:0005096; GO:0005634; GO:0090630 29291 XM_029347879.2 2280 1168 1106 2055 1780 Q86TI0 5.21e-31 TBC1 domain family member 1 Homo sapiens (Human) activation of GTPase activity [GO:0090630] GO:0005096; GO:0005634; GO:0090630 29292 XM_044307700.1 822 888 527 905 769 NA NA NA NA NA NA 29293 XM_044313270.1 0 0 28 23 20 A1A5X5 1.83e-29 Adipolin (Adipose-derived insulin-sensitizing factor) (Complement C1q tumor necrosis factor-related protein 12) Danio rerio (Zebrafish) (Brachydanio rerio) regulation of glucose import [GO:0046324]; Wnt signaling pathway [GO:0016055] GO:0005179; GO:0005576; GO:0005615; GO:0016055; GO:0046324 29294 XM_029324284.2 1289 679 734 719 1121 Q4PZA2 2.26e-143 Endothelin-converting enzyme 1 (ECE-1) (EC 3.4.24.71) Mus musculus (Mouse) apoptotic process [GO:0006915]; axonogenesis involved in innervation [GO:0060385]; blood vessel diameter maintenance [GO:0097746]; bradykinin catabolic process [GO:0010815]; calcitonin catabolic process [GO:0010816]; ear development [GO:0043583]; embryonic digit morphogenesis [GO:0042733]; embryonic heart tube development [GO:0035050]; endothelin maturation [GO:0034959]; gene expression [GO:0010467]; heart development [GO:0007507]; hormone catabolic process [GO:0042447]; neuron projection development [GO:0031175]; peptide hormone processing [GO:0016486]; pharyngeal system development [GO:0060037]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of receptor recycling [GO:0001921]; protein processing [GO:0016485]; regulation of blood pressure [GO:0008217]; regulation of ERK1 and ERK2 cascade [GO:0070372]; response to hypoxia [GO:0001666]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; substance P catabolic process [GO:0010814]; sympathetic neuron axon guidance [GO:0097492] GO:0001666; GO:0001921; GO:0004175; GO:0004222; GO:0005768; GO:0005769; GO:0005794; GO:0005886; GO:0006915; GO:0007507; GO:0008217; GO:0008270; GO:0009897; GO:0009986; GO:0010467; GO:0010613; GO:0010814; GO:0010815; GO:0010816; GO:0016020; GO:0016485; GO:0016486; GO:0030141; GO:0031175; GO:0031410; GO:0031982; GO:0033093; GO:0034959; GO:0035050; GO:0042447; GO:0042733; GO:0042802; GO:0042803; GO:0043583; GO:0043950; GO:0045745; GO:0048471; GO:0060037; GO:0060385; GO:0070372; GO:0097492; GO:0097746; GO:1902287 29295 XM_044326196.1 39 7 9 1 8 NA NA NA NA NA NA 29296 XM_029344862.2 17 11 7 25 13 Q6DIV6 4.75e-50 Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Solute carrier family 32 member 1) (Vesicular GABA transporter) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) beta-alanine transport [GO:0001762]; gamma-aminobutyric acid import [GO:0051939]; gamma-aminobutyric acid transport [GO:0015812]; glycine transport [GO:0015816]; neurotransmitter transport [GO:0006836] GO:0001762; GO:0006836; GO:0008021; GO:0015185; GO:0015187; GO:0015812; GO:0015816; GO:0030659; GO:0042995; GO:0051939; GO:0098793; GO:0140799; GO:0140800 29297 XR_006397535.1 33 19 38 22 125 NA NA NA NA NA NA 29298 XM_044313869.1 98 70 93 117 161 Q98993 2.19e-82 Verrucotoxin subunit beta (VTX subunit beta) Synanceia verrucosa (Reef stonefish) hemolysis in another organism [GO:0044179] GO:0005246; GO:0005576; GO:0015459; GO:0044179; GO:0090729 29299 XR_006392341.1 0 0 0 83 0 NA NA NA NA NA NA 29300 XR_003825323.2 18 3 3 3 35 Q9Y4C8 0 Probable RNA-binding protein 19 (RNA-binding motif protein 19) Homo sapiens (Human) mRNA splicing, via spliceosome [GO:0000398]; positive regulation of embryonic development [GO:0040019] GO:0000398; GO:0003723; GO:0005654; GO:0005694; GO:0005730; GO:0005737; GO:0016020; GO:0016607; GO:0040019 29301 XM_044309420.1 2 26 14 0 15 NA NA NA NA NA NA 29302 XM_029338222.2 10 0 0 0 0 Q60715 4.77e-109 Prolyl 4-hydroxylase subunit alpha-1 (4-PH alpha-1) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1) Mus musculus (Mouse) collagen fibril organization [GO:0030199]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401] GO:0004656; GO:0005506; GO:0005739; GO:0005783; GO:0005788; GO:0016222; GO:0018401; GO:0030199; GO:0031418; GO:0042802; GO:0043231 29303 XM_029351187.2 20 4 12 5 8 P02831 7.29e-24 Homeobox protein Hox-A3 (Homeobox protein Hox-1.5) (Homeobox protein MO-10) Mus musculus (Mouse) angiogenesis [GO:0001525]; animal organ formation [GO:0048645]; animal organ morphogenesis [GO:0009887]; anterior/posterior pattern specification [GO:0009952]; blood vessel remodeling [GO:0001974]; cartilage development [GO:0051216]; cell population proliferation [GO:0008283]; embryonic skeletal system development [GO:0048706]; embryonic skeletal system morphogenesis [GO:0048704]; gene expression [GO:0010467]; glossopharyngeal nerve morphogenesis [GO:0021615]; parathyroid gland development [GO:0060017]; positive regulation of stem cell proliferation [GO:2000648]; regulation of transcription by RNA polymerase II [GO:0006357]; specification of animal organ position [GO:0010159]; stem cell proliferation [GO:0072089]; thymus development [GO:0048538]; thyroid gland development [GO:0030878] GO:0000978; GO:0000981; GO:0001525; GO:0001974; GO:0003700; GO:0005634; GO:0005654; GO:0006357; GO:0008283; GO:0009887; GO:0009952; GO:0010159; GO:0010467; GO:0021615; GO:0030878; GO:0048538; GO:0048645; GO:0048704; GO:0048706; GO:0051216; GO:0060017; GO:0071837; GO:0072089; GO:2000648 29304 XM_044313669.1 48 79 49 77 60 C6FG12 1.44e-24 Protein NLRC5 Ictalurus punctatus (Channel catfish) (Silurus punctatus) innate immune response [GO:0045087] GO:0005524; GO:0005737; GO:0045087 29305 XM_044315283.1 0 15 0 0 86 NA NA NA NA NA NA 29306 XM_029355664.2 0 0 0 0 12 NA NA NA NA NA NA 29307 XM_029335795.2 0 0 79 19 0 Q8WV93 6.67e-101 AFG1-like ATPase (Lactation elevated protein 1) (EC 3.6.-.-) (Protein AFG1 homolog) Homo sapiens (Human) mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial protein catabolic process [GO:0035694]; mitochondrion organization [GO:0007005] GO:0005524; GO:0005737; GO:0005739; GO:0006123; GO:0007005; GO:0016887; GO:0031966; GO:0035694 29308 XR_003825818.2 30 28 23 12 78 NA NA NA NA NA NA 29309 XM_029344671.2 46 22 4 51 33 NA NA NA NA NA NA 29310 XM_044328862.1 6 32 9 0 12 NA NA NA NA NA NA 29311 XR_003824327.1 3 1 6 12 2 NA NA NA NA NA NA 29312 XM_029342565.2 6 3358 167 646 0 Q8R4V5 2.28e-27 Oncoprotein-induced transcript 3 protein (Liver-specific zona pellucida domain-containing protein) Mus musculus (Mouse) urate homeostasis [GO:1903118] GO:0005201; GO:0005509; GO:0005615; GO:0005635; GO:0009986; GO:1903118 29313 XM_029334823.2 7699 17372 7824 7645 5642 P00918 1.15e-75 Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase C) (CAC) (Carbonic anhydrase II) (CA-II) (Cyanamide hydratase CA2) (EC 4.2.1.69) Homo sapiens (Human) angiotensin-activated signaling pathway [GO:0038166]; carbon dioxide transport [GO:0015670]; morphogenesis of an epithelium [GO:0002009]; neuron cellular homeostasis [GO:0070050]; one-carbon metabolic process [GO:0006730]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; secretion [GO:0046903] GO:0002009; GO:0004064; GO:0004089; GO:0005737; GO:0005829; GO:0005886; GO:0006730; GO:0008270; GO:0015670; GO:0016836; GO:0018820; GO:0032230; GO:0032849; GO:0038166; GO:0043209; GO:0044070; GO:0045177; GO:0046903; GO:0051453; GO:0070050; GO:0070062; GO:2001150; GO:2001225 29314 XM_029344766.2 0 3 16 15 3 P35668 3.23e-115 Glutathione synthetase (GSH synthetase) (GSH-S) (EC 6.3.2.3) (Glutathione synthase) Xenopus laevis (African clawed frog) NA GO:0000287; GO:0004363; GO:0005524; GO:0042803; GO:0043295 29315 XR_003828523.2 3 0 64 10 0 NA NA NA NA NA NA 29316 XR_006394647.1 0 97 303 39 90 NA NA NA NA NA NA 29317 XM_044307271.1 490 535 297 665 509 NA NA NA NA NA NA 29318 XM_044313626.1 608 369 238 532 112 Q61153 8.86e-56 Type I iodothyronine deiodinase (EC 1.21.99.4) (5DI) (DIOI) (Type 1 DI) (Type-I 5'-deiodinase) Mus musculus (Mouse) amino acid metabolic process [GO:0006520]; hormone biosynthetic process [GO:0042446]; thyroid hormone metabolic process [GO:0042403] GO:0004800; GO:0005789; GO:0006520; GO:0008430; GO:0042403; GO:0042446 29319 XM_044327084.1 610 368 337 624 584 NA NA NA NA NA NA 29320 XM_044313680.1 6 0 0 120 12 NA NA NA NA NA NA 29321 XM_044325570.1 512 338 209 403 268 Q8BXN7 2.43e-85 Protein phosphatase 1K, mitochondrial (EC 3.1.3.16) (Protein phosphatase 2C isoform kappa) (PP2C-kappa) Mus musculus (Mouse) peptidyl-threonine dephosphorylation [GO:0035970] GO:0004722; GO:0005739; GO:0005759; GO:0017018; GO:0035970; GO:0046872 29322 XM_044314987.1 0 0 0 8 3 NA NA NA NA NA NA 29323 XM_029343023.2 1209 732 663 998 929 Q4QQS3 5.98e-145 Protein OSCP1 Rattus norvegicus (Rat) xenobiotic detoxification by transmembrane export across the plasma membrane [GO:1990961] GO:0005737; GO:0005886; GO:0009925; GO:0022857; GO:1990961 29324 XM_044319366.1 194 16 73 119 411 A0A2J6RX17 1.99e-32 NA NA NA NA 29325 XM_044328983.1 1 0 1 13 0 NA NA NA NA NA NA 29326 XM_029340260.2 1395 885 748 1092 984 NA NA NA NA NA NA 29327 XR_006392062.1 21 3 0 8 8 NA NA NA NA NA NA 29328 XM_029334191.2 295 216 11 177 194 Q149M9 8.55e-148 NACHT domain- and WD repeat-containing protein 1 Homo sapiens (Human) negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of gene expression [GO:0010628] GO:0005524; GO:0005730; GO:0005829; GO:0010628; GO:0032088 29329 XR_006396980.1 1208 645 44 524 328 NA NA NA NA NA NA 29330 XR_006397671.1 942 100 83 39 39 NA NA NA NA NA NA 29331 XR_006391509.1 22 0 52 54 17 NA NA NA NA NA NA 29332 XM_029340327.2 996 1174 461 533 330 A8E7G4 1.28e-112 DENN domain-containing protein 10 (Protein FAM45) (Protein FAM45A) Danio rerio (Zebrafish) (Brachydanio rerio) endosome transport via multivesicular body sorting pathway [GO:0032509]; protein transport [GO:0015031]; regulation of early endosome to late endosome transport [GO:2000641] GO:0005085; GO:0005770; GO:0015031; GO:0031267; GO:0032509; GO:2000641 29333 XM_029357224.2 15 0 28 43 73 Q866A2 4.14e-54 Neuronal acetylcholine receptor subunit alpha-7 Macaca mulatta (Rhesus macaque) associative learning [GO:0008306]; B cell activation [GO:0042113]; behavioral response to ethanol [GO:0048149]; behavioral response to nicotine [GO:0035095]; calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; cognition [GO:0050890]; dendrite arborization [GO:0140059]; dendritic spine organization [GO:0097061]; endocytosis [GO:0006897]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; generation of ovulation cycle rhythm [GO:0060112]; ion transmembrane transport [GO:0034220]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of tumor necrosis factor production [GO:0032720]; nervous system process [GO:0050877]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of CoA-transferase activity [GO:1905920]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure [GO:0001988]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; regulation of amyloid fibril formation [GO:1905906]; regulation of membrane potential [GO:0042391]; regulation of neuron death [GO:1901214]; regulation of norepinephrine secretion [GO:0014061]; regulation of synaptic transmission, dopaminergic [GO:0032225]; response to amyloid-beta [GO:1904645]; response to cold [GO:0009409]; response to food [GO:0032094]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; sensory processing [GO:0050893]; short-term memory [GO:0007614]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271]; T cell activation [GO:0042110] GO:0001540; GO:0001666; GO:0001933; GO:0001988; GO:0005231; GO:0005886; GO:0005892; GO:0006816; GO:0006874; GO:0006897; GO:0007165; GO:0007268; GO:0007271; GO:0007614; GO:0008284; GO:0008306; GO:0009409; GO:0009897; GO:0014061; GO:0015464; GO:0015643; GO:0016324; GO:0017081; GO:0022848; GO:0030317; GO:0030594; GO:0030673; GO:0032094; GO:0032225; GO:0032691; GO:0032715; GO:0032720; GO:0033138; GO:0034220; GO:0035094; GO:0035095; GO:0042110; GO:0042113; GO:0042166; GO:0042391; GO:0042734; GO:0042803; GO:0043005; GO:0043410; GO:0045202; GO:0045766; GO:0048149; GO:0050728; GO:0050877; GO:0050890; GO:0050893; GO:0051649; GO:0060112; GO:0070374; GO:0097061; GO:0098839; GO:0098978; GO:0098981; GO:0140059; GO:1900273; GO:1901214; GO:1902004; GO:1904315; GO:1904645; GO:1905906; GO:1905920; GO:2000463 29334 XM_044319599.1 6 9 0 72 8 NA NA NA NA NA NA 29335 XR_006391686.1 310 92 89 116 216 NA NA NA NA NA NA 29336 XM_044321967.1 260 196 118 147 164 Q8VZI2 6.73e-73 DUF21 domain-containing protein At4g33700 (CBS domain-containing protein CBSDUF6) Arabidopsis thaliana (Mouse-ear cress) magnesium ion homeostasis [GO:0010960] GO:0005886; GO:0010960; GO:0043231 29337 XR_003825169.2 55 47 48 0 40 NA NA NA NA NA NA 29338 XM_044319996.1 212 459 72 217 230 NA NA NA NA NA NA 29339 XM_029356298.2 398 376 143 73 172 Q5E985 4.43e-79 Hyaluronidase-1 (Hyal-1) (EC 3.2.1.35) (Hyaluronoglucosaminidase-1) Bos taurus (Bovine) carbohydrate metabolic process [GO:0005975]; cartilage development [GO:0051216]; cellular response to interleukin-1 [GO:0071347]; cellular response to pH [GO:0071467]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to UV-B [GO:0071493]; hyaluronan biosynthetic process [GO:0030213]; hyaluronan catabolic process [GO:0030214]; hyaluronan metabolic process [GO:0030212]; inflammatory response [GO:0006954]; negative regulation of cell growth [GO:0030308]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of growth [GO:0045927]; positive regulation of hyaluranon cable assembly [GO:1900106]; response to antibiotic [GO:0046677]; response to reactive oxygen species [GO:0000302]; response to virus [GO:0009615] GO:0000302; GO:0004415; GO:0005615; GO:0005737; GO:0005764; GO:0005975; GO:0006954; GO:0009615; GO:0010634; GO:0030212; GO:0030213; GO:0030214; GO:0030307; GO:0030308; GO:0031410; GO:0036117; GO:0036120; GO:0045766; GO:0045785; GO:0045927; GO:0046677; GO:0050501; GO:0050679; GO:0051216; GO:0071347; GO:0071467; GO:0071493; GO:1900087; GO:1900106 29340 XR_006395222.1 257 74 274 131 662 NA NA NA NA NA NA 29341 XM_044320063.1 62 10 27 103 0 B8EIZ7 2.05e-168 NA NA NA NA 29342 XM_044312508.1 0 7 0 10 0 NA NA NA NA NA NA 29343 XM_044312865.1 1044 748 213 1031 264 NA NA NA NA NA NA 29344 XM_029350147.2 1375 3264 994 1962 1448 NA NA NA NA NA NA 29345 XM_029347789.2 1032 960 607 784 669 Q3U1C6 5.51e-94 Putative deoxyribonuclease TATDN3 (EC 3.1.21.-) Mus musculus (Mouse) NA GO:0004518; GO:0005634; GO:0005739; GO:0046872 29346 XM_029340768.2 1240 1304 854 1021 984 NA NA NA NA NA NA 29347 XM_029349015.2 2 1 0 8 26 NA NA NA NA NA NA 29348 XM_044329037.1 90 12 27 31 45 NA NA NA NA NA NA 29349 XR_006394839.1 123 85 38 103 99 NA NA NA NA NA NA 29350 XM_044323301.1 14 38 0 5 9 Q5R5U3 9.93e-79 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 29351 XM_044323301.1 14 38 0 5 9 Q5R5U3 8.28e-76 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 29352 XM_044323301.1 14 38 0 5 9 Q5R5U3 8.46e-76 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 29353 XM_044323301.1 14 38 0 5 9 Q5R5U3 5.09e-75 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 29354 XM_044323301.1 14 38 0 5 9 Q5R5U3 6.48e-75 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 29355 XM_044323301.1 14 38 0 5 9 Q5R5U3 1.03e-73 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 29356 XM_044323301.1 14 38 0 5 9 Q5R5U3 1.49e-73 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 29357 XM_044323301.1 14 38 0 5 9 Q5R5U3 3.99e-71 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 29358 XM_044323301.1 14 38 0 5 9 Q5R5U3 6.61e-67 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 29359 XM_044323301.1 14 38 0 5 9 Q5R5U3 1.18e-64 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 29360 XM_029345865.2 43 0 1 0 666 Q8UW76 1.25e-103 T-box transcription factor TBX20 (T-box protein 20) (cTbx20) Gallus gallus (Chicken) aortic valve morphogenesis [GO:0003180]; atrial septum morphogenesis [GO:0060413]; atrioventricular canal development [GO:0036302]; blood circulation [GO:0008015]; branching involved in blood vessel morphogenesis [GO:0001569]; cardiac chamber formation [GO:0003207]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac right ventricle morphogenesis [GO:0003215]; cell fate specification [GO:0001708]; cell migration involved in heart development [GO:0060973]; cell proliferation involved in heart valve development [GO:2000793]; dorsal/ventral pattern formation [GO:0009953]; embryonic heart tube elongation [GO:0036306]; endocardial cushion formation [GO:0003272]; foramen ovale closure [GO:0035922]; heart looping [GO:0001947]; mesenchymal cell development [GO:0014031]; motor neuron migration [GO:0097475]; muscle contraction [GO:0006936]; negative regulation of gene expression [GO:0010629]; negative regulation of SMAD protein complex assembly [GO:0010991]; negative regulation of transcription by RNA polymerase II [GO:0000122]; outflow tract septum morphogenesis [GO:0003148]; pericardium morphogenesis [GO:0003344]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell migration [GO:0030335]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of gene expression [GO:0010628]; pulmonary valve formation [GO:0003193]; pulmonary vein morphogenesis [GO:0060577]; regulation of transcription by RNA polymerase II [GO:0006357]; tricuspid valve development [GO:0003175]; vasculogenesis [GO:0001570]; visceral motor neuron differentiation [GO:0021524] GO:0000122; GO:0000978; GO:0000981; GO:0001228; GO:0001569; GO:0001570; GO:0001708; GO:0001947; GO:0003148; GO:0003175; GO:0003180; GO:0003193; GO:0003207; GO:0003215; GO:0003272; GO:0003344; GO:0005634; GO:0005737; GO:0006357; GO:0006936; GO:0008015; GO:0009953; GO:0010628; GO:0010629; GO:0010718; GO:0010991; GO:0014031; GO:0021524; GO:0030335; GO:0030513; GO:0035922; GO:0036302; GO:0036306; GO:0055008; GO:0060045; GO:0060413; GO:0060577; GO:0060973; GO:0061629; GO:0097475; GO:2000793 29361 XM_029345675.2 1380 1154 1055 146 0 Q8K0Q5 1.91e-95 Rho GTPase-activating protein 18 (Rho-type GTPase-activating protein 18) Mus musculus (Mouse) regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin filament polymerization [GO:0030833]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of small GTPase mediated signal transduction [GO:0051056]; small GTPase mediated signal transduction [GO:0007264] GO:0001726; GO:0005096; GO:0005737; GO:0005829; GO:0005881; GO:0005886; GO:0007264; GO:0008360; GO:0016607; GO:0030833; GO:0032956; GO:0051056; GO:2000145 29362 XR_006392882.1 41 2 25 5 151 NA NA NA NA NA NA 29363 XM_044323010.1 292 142 186 199 255 B8UU78 0 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29364 XM_044306835.1 28 29 38 35 51 Q8N0P0 1e-26 Octopine dehydrogenase (OcDH) (EC 1.5.1.11) Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis) NA GO:0047830 29365 XM_029334656.2 157 114 67 354 372 Q08EN7 2.64e-27 Zinc finger CW-type PWWP domain protein 2 homolog Mus musculus (Mouse) NA GO:0005634; GO:0008270; GO:0035064 29366 XR_006396511.1 75 22 100 129 79 NA NA NA NA NA NA 29367 XM_044319763.1 19 0 23 31 73 NA NA NA NA NA NA 29368 XM_029344318.2 242 608 100 506 218 Q6AXP1 2.53e-23 Uncharacterized protein C19orf44 homolog Rattus norvegicus (Rat) NA NA 29369 XM_029342325.2 0 28 24 89 0 NA NA NA NA NA NA 29370 XM_029333747.2 1720 2478 1388 1682 1136 Q9CRA8 1.03e-69 Exosome complex component RRP46 (Exosome component 5) (Ribosomal RNA-processing protein 46) Mus musculus (Mouse) defense response to virus [GO:0051607]; DNA deamination [GO:0045006]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; nuclear mRNA surveillance [GO:0071028]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; U4 snRNA 3'-end processing [GO:0034475] GO:0000176; GO:0000177; GO:0000178; GO:0000791; GO:0003723; GO:0005634; GO:0005654; GO:0005730; GO:0005829; GO:0006364; GO:0006396; GO:0006401; GO:0016075; GO:0034427; GO:0034475; GO:0043928; GO:0045006; GO:0051607; GO:0071028; GO:0071051; GO:0101019 29371 XM_029348120.2 858 688 662 841 764 P38166 1.18e-28 Protein transport protein SFT2 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147] GO:0000138; GO:0000139; GO:0005829; GO:0015031; GO:0042147 29372 XR_006397109.1 217 356 128 76 91 NA NA NA NA NA NA 29373 XM_044315830.1 0 2 8 0 42 NA NA NA NA NA NA 29374 XM_029347620.2 28 8 39 43 70 NA NA NA NA NA NA 29375 XM_029332117.2 0 3 2 0 19 NA NA NA NA NA NA 29376 XM_029330584.2 351 220 168 315 304 NA NA NA NA NA NA 29377 XM_029340215.2 119 20 110 45 275 NA NA NA NA NA NA 29378 XM_044322559.1 0 0 68 44 105 NA NA NA NA NA NA 29379 XM_044328319.1 175 129 143 431 551 Q71RS6 9.45e-113 Sodium/potassium/calcium exchanger 5 (Na(+)/K(+)/Ca(2+)-exchange protein 5) (Solute carrier family 24 member 5) Homo sapiens (Human) calcium ion import [GO:0070509]; calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; melanin biosynthetic process [GO:0042438]; melanocyte differentiation [GO:0030318]; negative regulation of melanin biosynthetic process [GO:0048022]; response to stimulus [GO:0050896] GO:0005262; GO:0005802; GO:0006811; GO:0006874; GO:0008273; GO:0015293; GO:0030318; GO:0032588; GO:0034220; GO:0042438; GO:0042470; GO:0048022; GO:0050896; GO:0070509; GO:0070588 29380 XM_044308325.1 277 206 178 460 486 NA NA NA NA NA NA 29381 XM_029355904.2 22 0 11 4 0 NA NA NA NA NA NA 29382 XM_044318537.1 0 0 0 0 65 Q9UKZ1 0 CCR4-NOT transcription complex subunit 11 Homo sapiens (Human) mRNA catabolic process [GO:0006402]; negative regulation of translation [GO:0017148]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; RNA-mediated gene silencing [GO:0031047] GO:0000289; GO:0005634; GO:0005829; GO:0006402; GO:0017148; GO:0030014; GO:0031047 29383 XM_029348961.2 4623 6084 2765 5888 4091 Q9JMD3 3.07e-59 START domain-containing protein 10 (StARD10) (PCTP-like protein) (PCTP-L) (Serologically defined colon cancer antigen 28 homolog) (StAR-related lipid transfer protein 10) Mus musculus (Mouse) bile acid secretion [GO:0032782]; lipid transport [GO:0006869]; positive regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035360] GO:0005829; GO:0005902; GO:0006869; GO:0008289; GO:0016020; GO:0031514; GO:0032782; GO:0035360; GO:0046581 29384 XM_029341252.2 268 368 143 420 590 NA NA NA NA NA NA 29385 XM_029340736.2 149 332 169 365 500 Q05973 0 Sodium channel protein 1 brain (Sodium channel protein I brain) Heterololigo bleekeri (Spear squid) (Loligo bleekeri) regulation of ion transmembrane transport [GO:0034765] GO:0001518; GO:0005244; GO:0005248; GO:0034765 29386 XM_029340736.2 149 332 169 365 500 Q05973 1.09e-81 Sodium channel protein 1 brain (Sodium channel protein I brain) Heterololigo bleekeri (Spear squid) (Loligo bleekeri) regulation of ion transmembrane transport [GO:0034765] GO:0001518; GO:0005244; GO:0005248; GO:0034765 29387 XM_044317305.1 13 113 49 159 65 A0A2B4SES9 1.52e-92 NA NA NA NA 29388 XM_029332339.2 66 132 0 0 139 NA NA NA NA NA NA 29389 XM_029331195.2 1484 764 798 1212 1150 A7T167 0 Protein GDAP2 homolog Nematostella vectensis (Starlet sea anemone) NA NA 29390 XM_044309506.1 0 0 7 0 27 NA NA NA NA NA NA 29391 XM_029350375.2 63 45 0 49 46 Q24488 1.52e-82 Tyrosine-protein kinase transmembrane receptor Ror (dRor) (EC 2.7.10.1) Drosophila melanogaster (Fruit fly) central nervous system development [GO:0007417]; positive regulation of kinase activity [GO:0033674]; positive regulation of neuron projection development [GO:0010976]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0004713; GO:0004714; GO:0005524; GO:0005886; GO:0006468; GO:0007169; GO:0007417; GO:0010976; GO:0014068; GO:0016020; GO:0017147; GO:0033674; GO:0043235 29392 XM_044326998.1 0 0 0 0 40 NA NA NA NA NA NA 29393 XM_044325438.1 0 0 0 14 2 Q6QNK2 2.39e-63 Adhesion G-protein coupled receptor D1 (G-protein coupled receptor 133) (G-protein coupled receptor PGR25) Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0005654; GO:0005886; GO:0007166; GO:0007186; GO:0007189; GO:0016020 29394 XM_029357481.2 321 390 223 211 352 NA NA NA NA NA NA 29395 XM_044322614.1 365 0 46 147 71 NA NA NA NA NA NA 29396 XM_029350707.2 6208 6592 4155 4882 3201 Q9UN19 2.82e-58 Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide (hDAPP1) (B lymphocyte adapter protein Bam32) (B-cell adapter molecule of 32 kDa) Homo sapiens (Human) protein dephosphorylation [GO:0006470]; signal transduction [GO:0007165] GO:0005543; GO:0005547; GO:0005829; GO:0005886; GO:0006470; GO:0007165; GO:0043325 29397 XM_029342143.2 438 295 198 232 499 Q3UFB2 1.63e-57 Box C/D snoRNA protein 1 (Zinc finger HIT domain-containing protein 6) Mus musculus (Mouse) box C/D snoRNP assembly [GO:0000492]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; protein complex oligomerization [GO:0051259]; snoRNA localization [GO:0048254] GO:0000463; GO:0000492; GO:0001094; GO:0005634; GO:0019899; GO:0042802; GO:0046872; GO:0048254; GO:0051117; GO:0051259; GO:0070761 29398 XR_006397313.1 0 0 14 1 57 NA NA NA NA NA NA 29399 XM_029331474.2 114 63 11 30 13 Q9D2U5 3.79e-27 N-alpha-acetyltransferase 38, NatC auxiliary subunit (LSM domain-containing protein 1) Mus musculus (Mouse) negative regulation of apoptotic process [GO:0043066] GO:0005634; GO:0005654; GO:0005737; GO:0005844; GO:0031417; GO:0043066 29400 XM_029330509.2 176 243 161 275 180 NA NA NA NA NA NA 29401 XM_029357453.2 433 326 108 172 86 Q80TC6 0 Zinc finger SWIM domain-containing protein 5 Mus musculus (Mouse) NA GO:0008270; GO:0031462 29402 XM_044313276.1 158 118 73 175 89 Q6P3N9 2.25e-66 Zinc transporter 7 (ZnT-7) (Solute carrier family 30 member 7) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cellular zinc ion homeostasis [GO:0006882] GO:0005385; GO:0005794; GO:0006882; GO:0016020 29403 XM_029335201.2 11424 8971 4403 9574 7134 Q05975 5.88e-138 Ras-related protein Rab-2 Lymnaea stagnalis (Great pond snail) (Helix stagnalis) protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0003924; GO:0005525; GO:0005789; GO:0015031; GO:0016192; GO:0033116 29404 XM_044319716.1 60 31 4 0 0 NA NA NA NA NA NA 29405 XM_029355305.2 3997 3634 2732 2981 2744 A7RL75 5.17e-71 Tetratricopeptide repeat protein 36 homolog (TPR repeat protein 36 homolog) Nematostella vectensis (Starlet sea anemone) cilium assembly [GO:0060271] GO:0060271 29406 XM_029346153.2 0 0 59 138 0 Q9EPI9 0 Potassium voltage-gated channel subfamily H member 5 (Ether-a-go-go potassium channel 2) (rEAG2) (Voltage-gated potassium channel subunit Kv10.2) Rattus norvegicus (Rat) potassium ion transmembrane transport [GO:0071805]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391] GO:0005249; GO:0005516; GO:0005886; GO:0009986; GO:0010389; GO:0034765; GO:0042391; GO:0044325; GO:0044877; GO:0071805 29407 XM_029357331.2 0 38 0 30 0 Q05941 2.36e-75 Neuronal acetylcholine receptor subunit alpha-7 Rattus norvegicus (Rat) acetylcholine receptor signaling pathway [GO:0095500]; associative learning [GO:0008306]; B cell activation [GO:0042113]; behavioral response to ethanol [GO:0048149]; behavioral response to nicotine [GO:0035095]; calcium ion transport [GO:0006816]; cation transmembrane transport [GO:0098655]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; cognition [GO:0050890]; dendrite arborization [GO:0140059]; dendritic spine organization [GO:0097061]; dopamine biosynthetic process [GO:0042416]; endocytosis [GO:0006897]; establishment of localization in cell [GO:0051649]; excitatory postsynaptic potential [GO:0060079]; flagellated sperm motility [GO:0030317]; generation of ovulation cycle rhythm [GO:0060112]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; learning or memory [GO:0007611]; membrane depolarization [GO:0051899]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; modulation of excitatory postsynaptic potential [GO:0098815]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of tumor necrosis factor production [GO:0032720]; nervous system process [GO:0050877]; neuronal action potential [GO:0019228]; ovulation cycle [GO:0042698]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of CoA-transferase activity [GO:1905920]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure [GO:0001988]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of amyloid fibril formation [GO:1905906]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of inflammatory response [GO:0050727]; regulation of membrane potential [GO:0042391]; regulation of neuron death [GO:1901214]; regulation of nitric oxide metabolic process [GO:0080164]; regulation of norepinephrine secretion [GO:0014061]; regulation of response to drug [GO:2001023]; regulation of synaptic transmission, dopaminergic [GO:0032225]; response to acetylcholine [GO:1905144]; response to amyloid-beta [GO:1904645]; response to carbamate [GO:0046681]; response to cold [GO:0009409]; response to ethanol [GO:0045471]; response to food [GO:0032094]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; sensory processing [GO:0050893]; signal transduction [GO:0007165]; synapse organization [GO:0050808]; synaptic transmission, cholinergic [GO:0007271]; T cell activation [GO:0042110] GO:0001540; GO:0001666; GO:0001933; GO:0001934; GO:0001988; GO:0005216; GO:0005231; GO:0005737; GO:0005886; GO:0005892; GO:0006811; GO:0006816; GO:0006874; GO:0006897; GO:0007165; GO:0007268; GO:0007271; GO:0007611; GO:0007613; GO:0008179; GO:0008284; GO:0008306; GO:0009409; GO:0009897; GO:0010628; GO:0014061; GO:0014069; GO:0015464; GO:0015643; GO:0016020; GO:0016324; GO:0017081; GO:0019228; GO:0019901; GO:0022848; GO:0030317; GO:0030424; GO:0030425; GO:0030426; GO:0030594; GO:0030673; GO:0032094; GO:0032225; GO:0032279; GO:0032691; GO:0032715; GO:0032720; GO:0033138; GO:0034220; GO:0035094; GO:0035095; GO:0042110; GO:0042113; GO:0042166; GO:0042391; GO:0042416; GO:0042698; GO:0042734; GO:0042803; GO:0043005; GO:0043025; GO:0043197; GO:0043198; GO:0043410; GO:0044853; GO:0045121; GO:0045202; GO:0045211; GO:0045471; GO:0045766; GO:0046681; GO:0048149; GO:0050727; GO:0050728; GO:0050804; GO:0050808; GO:0050877; GO:0050890; GO:0050893; GO:0051117; GO:0051247; GO:0051649; GO:0051899; GO:0060079; GO:0060112; GO:0070373; GO:0070374; GO:0080164; GO:0095500; GO:0097061; GO:0097110; GO:0098655; GO:0098690; GO:0098815; GO:0098897; GO:0098981; GO:0099171; GO:0099634; GO:0140059; GO:1900273; GO:1901214; GO:1902004; GO:1902430; GO:1902991; GO:1904315; GO:1904645; GO:1905144; GO:1905906; GO:1905920; GO:2000463; GO:2001023 29408 XM_029337036.2 4 4 10 35 24 Q8HYZ1 5.03e-99 Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2) Mustela putorius furo (European domestic ferret) (Mustela furo) cardiac muscle cell action potential [GO:0086001]; cellular response to hypoxia [GO:0071456]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005250; GO:0005886; GO:0005901; GO:0008076; GO:0030315; GO:0032809; GO:0034765; GO:0042383; GO:0043197; GO:0043204; GO:0044853; GO:0045211; GO:0046872; GO:0051260; GO:0070161; GO:0071456; GO:0071805; GO:0086001 29409 XM_029356820.2 195 83 256 323 333 NA NA NA NA NA NA 29410 XM_044325181.1 10 0 5 0 22 NA NA NA NA NA NA 29411 XM_044326101.1 0 2 0 0 6 NA NA NA NA NA NA 29412 XM_044310551.1 14 12 10 34 68 Q94K49 1.71e-40 Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1 (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) epigenetic regulation of gene expression [GO:0040029] GO:0003682; GO:0004518; GO:0005634; GO:0035098; GO:0035102; GO:0040029; GO:0046872 29413 XM_044321913.1 0 348 632 1312 276 O94827 1.63e-85 Pleckstrin homology domain-containing family G member 5 (PH domain-containing family G member 5) (Guanine nucleotide exchange factor 720) (GEF720) Homo sapiens (Human) endothelial cell chemotaxis [GO:0035767]; endothelial cell migration [GO:0043542]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266] GO:0005085; GO:0005737; GO:0005829; GO:0005886; GO:0005911; GO:0007266; GO:0030027; GO:0030139; GO:0030424; GO:0035767; GO:0043123; GO:0043542; GO:0048471; GO:0051056 29414 XM_029349072.2 831 752 423 877 798 Q6ZU65 2.52e-51 Ubinuclein-2 Homo sapiens (Human) NA GO:0005615; GO:0005634; GO:0005654 29415 XM_029328603.2 355 71 345 529 673 Q8R3F5 5.42e-68 Malonyl-CoA-acyl carrier protein transacylase, mitochondrial (MCT) (EC 2.3.1.39) (Mitochondrial malonyltransferase) ([Acyl-carrier-protein] malonyltransferase) Mus musculus (Mouse) fatty acid biosynthetic process [GO:0006633] GO:0004312; GO:0004314; GO:0005739; GO:0006633 29416 XM_029324747.2 0 0 0 8 12 Q96P65 6.17e-21 Pyroglutamylated RF-amide peptide receptor (AQ27) (G-protein coupled receptor 103) (Orexigenic neuropeptide QRFP receptor) (SP9155) Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:0016020 29417 XM_044327452.1 0 0 16 0 0 O43854 1.07e-27 EGF-like repeat and discoidin I-like domain-containing protein 3 (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1) Homo sapiens (Human) cell adhesion [GO:0007155]; positive regulation of cell-substrate adhesion [GO:0010811] GO:0005178; GO:0005509; GO:0007155; GO:0010811; GO:0062023; GO:0070062; GO:1903561 29418 XM_029330747.2 445 330 149 232 389 Q8K4T5 4.66e-48 Dual specificity protein phosphatase 19 (EC 3.1.3.16) (EC 3.1.3.48) (Protein phosphatase SKRP1) (Stress-activated protein kinase pathway-regulating phosphatase 1) Mus musculus (Mouse) JNK cascade [GO:0007254]; negative regulation of JNK cascade [GO:0046329]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein kinase activity [GO:0045860]; protein dephosphorylation [GO:0006470]; regulation of MAP kinase activity [GO:0043405] GO:0004725; GO:0004860; GO:0005078; GO:0005737; GO:0006469; GO:0006470; GO:0007254; GO:0008138; GO:0008330; GO:0008579; GO:0017018; GO:0030295; GO:0031434; GO:0031435; GO:0043405; GO:0043409; GO:0043410; GO:0043507; GO:0043508; GO:0045860; GO:0046329; GO:0046330 29419 XM_029354500.2 9 2 5 10 24 NA NA NA NA NA NA 29420 XM_044317778.1 117 23 70 61 131 NA NA NA NA NA NA 29421 XM_029332807.2 0 0 89 0 346 Q9UPM8 6.47e-156 AP-4 complex subunit epsilon-1 (AP-4 adaptor complex subunit epsilon) (Adaptor-related protein complex 4 subunit epsilon-1) (Epsilon subunit of AP-4) (Epsilon-adaptin) Homo sapiens (Human) protein localization [GO:0008104]; protein targeting [GO:0006605]; vesicle-mediated transport [GO:0016192] GO:0005802; GO:0006605; GO:0008104; GO:0016192; GO:0030124; GO:0031904; GO:0032588; GO:0140312 29422 XM_029336320.2 32 7 46 75 31 NA NA NA NA NA NA 29423 XM_044316541.1 278 152 215 304 958 NA NA NA NA NA NA 29424 XM_029342850.2 1 3 0 26 9 NA NA NA NA NA NA 29425 XM_029343066.2 0 0 14 5 1 P54833 4.55e-25 Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor) Canis lupus familiaris (Dog) (Canis familiaris) activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; desensitization of G protein-coupled receptor signaling pathway by arrestin [GO:0002032]; negative regulation of smooth muscle contraction [GO:0045986]; norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0002025]; positive regulation of autophagosome maturation [GO:1901098]; positive regulation of lipophagy [GO:1904504]; positive regulation of MAPK cascade [GO:0043410]; receptor-mediated endocytosis [GO:0006898] GO:0002025; GO:0002032; GO:0004930; GO:0004941; GO:0005769; GO:0005794; GO:0005886; GO:0006898; GO:0007190; GO:0042803; GO:0043235; GO:0043410; GO:0045986; GO:0051380; GO:0071880; GO:1901098; GO:1904504 29426 XM_029332642.2 3791 5041 2050 2972 3212 Q9YGD2 1.16e-126 Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial (EC 6.2.1.4) (EC 6.2.1.5) (Succinyl-CoA synthetase subunit alpha) (SCS-alpha) Columba livia (Rock dove) tricarboxylic acid cycle [GO:0006099] GO:0000166; GO:0004775; GO:0004776; GO:0005739; GO:0006099 29427 XM_029338116.2 677 215 246 426 478 Q9GLK0 2.56e-164 Protein-glutamine gamma-glutamyltransferase K (EC 2.3.2.13) (Epidermal TGase) (Transglutaminase K) (TG(K)) (TGK) (TGase K) (Transglutaminase-1) (TGase-1) Canis lupus familiaris (Dog) (Canis familiaris) keratinization [GO:0031424]; peptide cross-linking [GO:0018149]; positive regulation of cell cycle [GO:0045787]; positive regulation of keratinocyte proliferation [GO:0010838] GO:0003810; GO:0010838; GO:0016020; GO:0018149; GO:0031424; GO:0045787; GO:0046872 29428 XM_044326681.1 753 2221 1463 1198 1159 Q8QZR1 1.1e-165 Tyrosine aminotransferase (TAT) (EC 2.6.1.5) (L-tyrosine:2-oxoglutarate aminotransferase) Mus musculus (Mouse) 2-oxoglutarate metabolic process [GO:0006103]; amino acid metabolic process [GO:0006520]; biosynthetic process [GO:0009058]; glutamate metabolic process [GO:0006536]; L-phenylalanine catabolic process [GO:0006559]; response to dexamethasone [GO:0071548]; response to glucocorticoid [GO:0051384]; response to mercury ion [GO:0046689]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; tyrosine catabolic process [GO:0006572] GO:0004838; GO:0005739; GO:0006103; GO:0006520; GO:0006536; GO:0006559; GO:0006572; GO:0006979; GO:0009058; GO:0014070; GO:0016597; GO:0030170; GO:0042802; GO:0046689; GO:0051384; GO:0071548 29429 XM_044311655.1 16 0 3 1 0 B8VIU6 8.93e-68 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 29430 XM_029329036.2 107 60 79 178 161 Q8CGF5 3.33e-54 TLC domain-containing protein 4 (Transmembrane protein 56) Mus musculus (Mouse) lipid homeostasis [GO:0055088] GO:0005783; GO:0016020; GO:0055088 29431 XR_006397332.1 128 148 2 87 45 NA NA NA NA NA NA 29432 XM_044328561.1 204 240 350 410 528 P41413 7.76e-110 Proprotein convertase subtilisin/kexin type 5 (EC 3.4.21.-) (Proprotein convertase 5) (PC5) (Proprotein convertase 6) (PC6) (Subtilisin/kexin-like protease PC5) (rPC5) Rattus norvegicus (Rat) anterior/posterior pattern specification [GO:0009952]; cardiac septum development [GO:0003279]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; coronary vasculature development [GO:0060976]; cytokine precursor processing [GO:0140447]; determination of left/right symmetry [GO:0007368]; embryo implantation [GO:0007566]; embryonic digestive tract development [GO:0048566]; embryonic skeletal system development [GO:0048706]; heart development [GO:0007507]; kidney development [GO:0001822]; limb morphogenesis [GO:0035108]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of integrin activation [GO:0033625]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of smooth muscle cell-matrix adhesion [GO:1905609]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; protein processing [GO:0016485]; renin secretion into blood stream [GO:0002001]; respiratory tube development [GO:0030323]; response to gonadotropin [GO:0034698]; response to luteinizing hormone [GO:0034699]; signal peptide processing [GO:0006465]; vascular associated smooth muscle cell proliferation [GO:1990874]; viral life cycle [GO:0019058] GO:0000139; GO:0001822; GO:0002001; GO:0003279; GO:0004175; GO:0004252; GO:0005615; GO:0005794; GO:0005797; GO:0005802; GO:0005886; GO:0006465; GO:0007368; GO:0007507; GO:0007566; GO:0008233; GO:0009952; GO:0016020; GO:0016485; GO:0016486; GO:0019058; GO:0030323; GO:0033625; GO:0034698; GO:0034699; GO:0035108; GO:0036120; GO:0042277; GO:0043043; GO:0043204; GO:0048566; GO:0048706; GO:0060976; GO:0140447; GO:1904754; GO:1905609; GO:1990635; GO:1990874; GO:2001046 29433 XR_006396781.1 74792 404757 524014 239164 219608 NA NA NA NA NA NA 29434 XM_029347585.2 3 0 2 4 18 NA NA NA NA NA NA 29435 XM_029334620.2 0 0 0 49 91 Q148G4 1.11e-117 Deoxyribonuclease TATDN1 (EC 3.1.21.-) Bos taurus (Bovine) NA GO:0005654; GO:0008296; GO:0046872 29436 XR_006392831.1 0 6 0 0 0 NA NA NA NA NA NA 29437 XM_029355491.2 1465 1109 760 933 675 A1A4N1 4.5e-83 Equilibrative nucleoside transporter 3 (Solute carrier family 29 member 3) Bos taurus (Bovine) NA GO:0005337; GO:0005765; GO:0031902 29438 XM_044322384.1 68 88 75 50 158 P10394 4.61e-47 Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 29439 XM_044324912.1 666 311 516 656 277 Q9UQ26 1.73e-63 Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2) (Rab-3-interacting protein 3) Homo sapiens (Human) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-ion regulated exocytosis [GO:0017156]; cell differentiation [GO:0030154]; insulin secretion [GO:0030073]; intracellular protein transport [GO:0006886]; positive regulation of dendrite extension [GO:1903861]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of synaptic transmission [GO:0050806]; regulation of exocytosis [GO:0017157]; regulation of membrane potential [GO:0042391]; regulation of synaptic plasticity [GO:0048167]; spontaneous neurotransmitter secretion [GO:0061669] GO:0006886; GO:0007188; GO:0017156; GO:0017157; GO:0030073; GO:0030154; GO:0031267; GO:0042391; GO:0042734; GO:0042995; GO:0044325; GO:0046872; GO:0048167; GO:0048786; GO:0048788; GO:0048791; GO:0050806; GO:0061669; GO:0070062; GO:0097151; GO:1903861; GO:2000463 29440 XM_044324912.1 666 311 516 656 277 Q9UQ26 1.39e-30 Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2) (Rab-3-interacting protein 3) Homo sapiens (Human) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-ion regulated exocytosis [GO:0017156]; cell differentiation [GO:0030154]; insulin secretion [GO:0030073]; intracellular protein transport [GO:0006886]; positive regulation of dendrite extension [GO:1903861]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of synaptic transmission [GO:0050806]; regulation of exocytosis [GO:0017157]; regulation of membrane potential [GO:0042391]; regulation of synaptic plasticity [GO:0048167]; spontaneous neurotransmitter secretion [GO:0061669] GO:0006886; GO:0007188; GO:0017156; GO:0017157; GO:0030073; GO:0030154; GO:0031267; GO:0042391; GO:0042734; GO:0042995; GO:0044325; GO:0046872; GO:0048167; GO:0048786; GO:0048788; GO:0048791; GO:0050806; GO:0061669; GO:0070062; GO:0097151; GO:1903861; GO:2000463 29441 XM_029351641.2 185 68 125 87 79 P57772 0 Selenocysteine-specific elongation factor (Elongation factor sec) (Eukaryotic elongation factor, selenocysteine-tRNA-specific) Homo sapiens (Human) selenocysteine incorporation [GO:0001514]; translational elongation [GO:0006414] GO:0000049; GO:0001514; GO:0003746; GO:0003924; GO:0005525; GO:0005634; GO:0005737; GO:0006414; GO:0035368; GO:0043021; GO:1990904 29442 XM_029335117.2 284 240 167 226 243 Q3B8H3 1.07e-70 Transmembrane protein 11-B, mitochondrial Xenopus laevis (African clawed frog) mitochondrion organization [GO:0007005] GO:0005743; GO:0007005 29443 XM_029324600.2 453 335 889 157 199 NA NA NA NA NA NA 29444 XM_044320633.1 544 11 478 97 258 NA NA NA NA NA NA 29445 XM_044311650.1 0 0 0 0 6 NA NA NA NA NA NA 29446 XM_044312571.1 0 119 82 0 139 Q5XFW6 2.05e-112 WD repeat-containing protein 6 Rattus norvegicus (Rat) G1 to G0 transition [GO:0070314]; insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009]; negative regulation of autophagy [GO:0010507]; negative regulation of cell population proliferation [GO:0008285]; tRNA methylation [GO:0030488] GO:0005737; GO:0008285; GO:0008286; GO:0010507; GO:0030488; GO:0032991; GO:0043560; GO:0048009; GO:0070314 29447 XM_029356810.2 1687 1948 1762 2103 2850 NA NA NA NA NA NA 29448 XM_029349874.2 3359 4323 3027 2408 1830 A8E4L1 7.65e-24 Cytochrome c oxidase assembly protein COX19 Bos taurus (Bovine) cellular copper ion homeostasis [GO:0006878]; mitochondrial cytochrome c oxidase assembly [GO:0033617] GO:0005739; GO:0005758; GO:0005829; GO:0006878; GO:0033617 29449 XM_044312144.1 0 0 6 0 0 NA NA NA NA NA NA 29450 XM_044317320.1 0 2 20 0 130 NA NA NA NA NA NA 29451 XM_029349177.2 3462 3911 1772 2295 1151 NA NA NA NA NA NA 29452 XM_029342121.2 265 243 170 432 199 NA NA NA NA NA NA 29453 XM_029340084.2 59 0 22 69 88 NA NA NA NA NA NA 29454 XM_044315605.1 72 2 24 4 8 NA NA NA NA NA NA 29455 XM_029344791.2 0 116 0 299 547 Q8BIQ5 4.98e-83 Cleavage stimulation factor subunit 2 (CF-1 64 kDa subunit) (Cleavage stimulation factor 64 kDa subunit) (CSTF 64 kDa subunit) (CstF-64) Mus musculus (Mouse) cellular response to nerve growth factor stimulus [GO:1990090]; pre-mRNA cleavage required for polyadenylation [GO:0098789] GO:0003723; GO:0003729; GO:0005654; GO:0005847; GO:0016604; GO:0071920; GO:0098789; GO:1990090 29456 XM_044306938.1 62 0 0 0 128 NA NA NA NA NA NA 29457 XM_029340500.2 1369 2644 1087 2211 1783 Q3TZA2 7.85e-153 Cyclin-dependent kinase-like 4 (EC 2.7.11.22) Mus musculus (Mouse) protein phosphorylation [GO:0006468] GO:0004693; GO:0005524; GO:0005634; GO:0005737; GO:0006468; GO:0106310 29458 XM_044319015.1 624 220 103 470 206 Q09328 5.43e-178 Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (EC 2.4.1.155) (Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase V) (GlcNAc-T V) (GNT-V) (Mannoside acetylglucosaminyltransferase 5) (N-acetylglucosaminyl-transferase V) [Cleaved into: Secreted alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (Secreted beta-1,6-N-acetylglucosaminyltransferase V) (Secreted GNT-V)] Homo sapiens (Human) negative regulation of protein tyrosine phosphatase activity [GO:1903614]; positive regulation of cell migration [GO:0030335]; positive regulation of receptor signaling pathway via STAT [GO:1904894]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279]; viral protein processing [GO:0019082] GO:0000139; GO:0004864; GO:0005794; GO:0006487; GO:0016020; GO:0018279; GO:0019082; GO:0030144; GO:0030145; GO:0030335; GO:0070062; GO:1903614; GO:1904894 29459 XM_044316557.1 17 0 10 52 72 NA NA NA NA NA NA 29460 XR_003827410.2 74 56 32 85 37 Q9HC58 2.06e-73 Sodium/potassium/calcium exchanger 3 (Na(+)/K(+)/Ca(2+)-exchange protein 3) (Solute carrier family 24 member 3) Homo sapiens (Human) bone mineralization [GO:0030282]; calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; ion transport [GO:0006811]; negative regulation of gene expression [GO:0010629]; positive regulation of gene expression [GO:0010628]; potassium ion transmembrane transport [GO:0071805]; sodium ion transmembrane transport [GO:0035725]; transport across blood-brain barrier [GO:0150104] GO:0005262; GO:0005886; GO:0006811; GO:0006874; GO:0008273; GO:0010628; GO:0010629; GO:0015293; GO:0030282; GO:0035725; GO:0070588; GO:0071805; GO:0071944; GO:0150104 29461 XR_003827410.2 74 56 32 85 37 Q9HC58 7.08e-22 Sodium/potassium/calcium exchanger 3 (Na(+)/K(+)/Ca(2+)-exchange protein 3) (Solute carrier family 24 member 3) Homo sapiens (Human) bone mineralization [GO:0030282]; calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; ion transport [GO:0006811]; negative regulation of gene expression [GO:0010629]; positive regulation of gene expression [GO:0010628]; potassium ion transmembrane transport [GO:0071805]; sodium ion transmembrane transport [GO:0035725]; transport across blood-brain barrier [GO:0150104] GO:0005262; GO:0005886; GO:0006811; GO:0006874; GO:0008273; GO:0010628; GO:0010629; GO:0015293; GO:0030282; GO:0035725; GO:0070588; GO:0071805; GO:0071944; GO:0150104 29462 XM_029347816.2 587 288 194 369 479 Q9NXH9 0 tRNA (guanine(26)-N(2))-dimethyltransferase (EC 2.1.1.216) (tRNA 2,2-dimethylguanosine-26 methyltransferase) (tRNA(guanine-26,N(2)-N(2)) methyltransferase) (tRNA(m(2,2)G26)dimethyltransferase) Homo sapiens (Human) tRNA modification [GO:0006400]; tRNA N2-guanine methylation [GO:0002940] GO:0000049; GO:0002940; GO:0003723; GO:0004809; GO:0005634; GO:0005654; GO:0006400; GO:0046872 29463 XM_044307562.1 0 513 0 0 428 P23790 5.03e-64 Serum response factor (SRF) Xenopus laevis (African clawed frog) actin cytoskeleton organization [GO:0030036]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000981; GO:0003700; GO:0005634; GO:0010736; GO:0030036; GO:0045944; GO:0046983 29464 XM_044309249.1 0 9 37 60 69 NA NA NA NA NA NA 29465 XM_029355914.2 0 55 0 0 45 C9D7C2 0 Voltage-dependent calcium channel type A subunit alpha-1 (Cacophony protein) Apis mellifera (Honeybee) regulation of ion transmembrane transport [GO:0034765] GO:0005245; GO:0005509; GO:0005891; GO:0034765 29466 XM_044317223.1 827 788 349 541 551 O35231 1.02e-175 Kinesin-like protein KIFC3 Mus musculus (Mouse) epithelial cell-cell adhesion [GO:0090136]; Golgi organization [GO:0007030]; microtubule-based movement [GO:0007018]; microtubule-based process [GO:0007017]; zonula adherens maintenance [GO:0045218] GO:0005524; GO:0005794; GO:0005813; GO:0005871; GO:0005874; GO:0005915; GO:0007017; GO:0007018; GO:0007030; GO:0008017; GO:0008569; GO:0015630; GO:0030659; GO:0042802; GO:0045218; GO:0090136 29467 XR_006394281.1 1 5 0 13 5 NA NA NA NA NA NA 29468 XM_044318525.1 129 144 59 149 108 P0CI65 2.16e-47 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 29469 XM_044318525.1 129 144 59 149 108 P0CI65 4.52e-44 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 29470 XM_044318525.1 129 144 59 149 108 P0CI65 1.91e-36 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 29471 XM_044318525.1 129 144 59 149 108 P0CI65 1.91e-36 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 29472 XM_044318525.1 129 144 59 149 108 P0CI65 1.37e-35 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 29473 XM_044324402.1 2040 424 227 243 719 Q3ZBV2 0 ATP-dependent RNA helicase DDX19A (EC 3.6.4.13) (DEAD box protein 19A) Bos taurus (Bovine) poly(A)+ mRNA export from nucleus [GO:0016973] GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005654; GO:0010494; GO:0016887; GO:0016973 29474 XM_044324402.1 2040 424 227 243 719 Q3ZBV2 0 ATP-dependent RNA helicase DDX19A (EC 3.6.4.13) (DEAD box protein 19A) Bos taurus (Bovine) poly(A)+ mRNA export from nucleus [GO:0016973] GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005654; GO:0010494; GO:0016887; GO:0016973 29475 XM_044324402.1 2040 424 227 243 719 Q3ZBV2 3.81e-42 ATP-dependent RNA helicase DDX19A (EC 3.6.4.13) (DEAD box protein 19A) Bos taurus (Bovine) poly(A)+ mRNA export from nucleus [GO:0016973] GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005654; GO:0010494; GO:0016887; GO:0016973 29476 XM_044308281.1 142 206 125 261 319 Q7Z020 1.04e-118 Transient receptor potential cation channel subfamily A member 1 (dTRPA1) (Ankyrin-like with transmembrane domains protein 1) (dANKTM1) Drosophila melanogaster (Fruit fly) calcium ion transport [GO:0006816]; cation transport [GO:0006812]; cellular response to heat [GO:0034605]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; detection of temperature stimulus involved in thermoception [GO:0050960]; mechanosensory behavior [GO:0007638]; negative phototaxis [GO:0046957]; neuronal signal transduction [GO:0023041]; phototransduction [GO:0007602]; positive regulation of calcium-mediated signaling [GO:0050850]; response to heat [GO:0009408]; response to light stimulus [GO:0009416]; temperature compensation of the circadian clock [GO:0010378]; thermosensory behavior [GO:0040040]; thermotaxis [GO:0043052] GO:0001580; GO:0005261; GO:0005262; GO:0005886; GO:0006812; GO:0006816; GO:0007602; GO:0007638; GO:0009408; GO:0009416; GO:0010378; GO:0015276; GO:0016020; GO:0023041; GO:0034605; GO:0034703; GO:0040040; GO:0043052; GO:0046957; GO:0050850; GO:0050960; GO:0050965; GO:0050968; GO:0097604 29477 XM_029349414.2 110 41 26 48 65 NA NA NA NA NA NA 29478 XM_044317728.1 17 5 2 14 3 NA NA NA NA NA NA 29479 XM_044327219.1 1598 2112 812 1045 824 Q9D5W8 3.05e-36 Testis-expressed protein 47 Mus musculus (Mouse) NA NA 29480 XM_029338224.2 7 13 0 10 23 Q5RAG8 2.27e-74 Prolyl 4-hydroxylase subunit alpha-1 (4-PH alpha-1) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0004656; GO:0005506; GO:0005739; GO:0005788; GO:0031418; GO:0042802 29481 XM_044316064.1 861 247 295 771 423 E7F7V7 5.77e-24 Galanin receptor 2b Danio rerio (Zebrafish) (Brachydanio rerio) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; neuropeptide signaling pathway [GO:0007218] GO:0004966; GO:0005886; GO:0007188; GO:0007218; GO:0008528 29482 XM_029340884.2 848 571 580 1028 1187 Q0V7M0 0 Importin subunit alpha-7 (Karyopherin subunit alpha-6) Bos taurus (Bovine) NLS-bearing protein import into nucleus [GO:0006607] GO:0005634; GO:0005654; GO:0005737; GO:0006607; GO:0008139; GO:0061608 29483 XR_006394775.1 1031 2498 1459 2682 3825 Q9MZ30 3.02e-36 Carbonic anhydrase 12 (EC 4.2.1.1) (Carbonate dehydratase XII) (Carbonic anhydrase XII) (CA-XII) Oryctolagus cuniculus (Rabbit) NA GO:0004089; GO:0005886; GO:0008270 29484 XR_006394775.1 1031 2498 1459 2682 3825 Q9MZ30 3.02e-36 Carbonic anhydrase 12 (EC 4.2.1.1) (Carbonate dehydratase XII) (Carbonic anhydrase XII) (CA-XII) Oryctolagus cuniculus (Rabbit) NA GO:0004089; GO:0005886; GO:0008270 29485 XM_029348267.2 41 32 13 11 62 NA NA NA NA NA NA 29486 XM_044326303.1 941 717 443 1073 941 O60094 5.62e-48 rDNA transcriptional regulator pol5 (DNA polymerase V) (POL V) (DNA polymerase phi) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) regulation of DNA-templated transcription [GO:0006355]; rRNA processing [GO:0006364]; rRNA transcription [GO:0009303] GO:0000166; GO:0000182; GO:0001163; GO:0005634; GO:0005730; GO:0005829; GO:0006355; GO:0006364; GO:0009303 29487 XR_006393479.1 151 78 97 159 201 NA NA NA NA NA NA 29488 XM_044324751.1 134 20 97 111 27 Q9SSA4 3.95e-26 NA NA NA NA 29489 XM_044321369.1 334 46 114 0 294 NA NA NA NA NA NA 29490 XM_044323247.1 227 1150 591 1158 572 B8V7S0 0 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 29491 XM_044323247.1 227 1150 591 1158 572 B8V7S0 6.17e-33 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 29492 XM_044323247.1 227 1150 591 1158 572 B8V7S0 2.54e-30 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 29493 XM_044323247.1 227 1150 591 1158 572 B8V7S0 1.91e-27 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 29494 XM_044323247.1 227 1150 591 1158 572 B8V7S0 2.2e-24 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 29495 XR_006391681.1 30 25 12 0 12 NA NA NA NA NA NA 29496 XM_044325359.1 5 0 35 3 5 NA NA NA NA NA NA 29497 XR_006397898.1 1433 2387 737 367 1290 NA NA NA NA NA NA 29498 XM_029351320.2 1910 1593 1165 1622 1491 O00499 2.51e-56 Myc box-dependent-interacting protein 1 (Amphiphysin II) (Amphiphysin-like protein) (Box-dependent myc-interacting protein 1) (Bridging integrator 1) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endocytosis [GO:0006897]; endosome to lysosome transport [GO:0008333]; lipid tube assembly [GO:0060988]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902960]; negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel [GO:1904878]; negative regulation of potassium ion transmembrane transport [GO:1901380]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of ventricular cardiac muscle cell action potential [GO:1903946]; nucleus localization [GO:0051647]; nucleus organization [GO:0006997]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of apoptotic process [GO:0043065]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of endocytosis [GO:0045807]; positive regulation of GTPase activity [GO:0043547]; regulation of cell cycle process [GO:0010564]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of neuron differentiation [GO:0045664]; synaptic vesicle endocytosis [GO:0048488]; T-tubule organization [GO:0033292] GO:0000122; GO:0002020; GO:0005543; GO:0005634; GO:0005635; GO:0005737; GO:0005768; GO:0005829; GO:0005886; GO:0006897; GO:0006997; GO:0007010; GO:0008021; GO:0008333; GO:0010564; GO:0015629; GO:0016020; GO:0019828; GO:0030018; GO:0030276; GO:0030315; GO:0030424; GO:0030425; GO:0030838; GO:0031674; GO:0031982; GO:0033268; GO:0033292; GO:0042802; GO:0043065; GO:0043194; GO:0043196; GO:0043547; GO:0043679; GO:0044300; GO:0045664; GO:0045807; GO:0048156; GO:0048488; GO:0048711; GO:0051015; GO:0051020; GO:0051087; GO:0051647; GO:0060987; GO:0060988; GO:0070063; GO:0086091; GO:0090571; GO:0098850; GO:0098978; GO:1901380; GO:1902430; GO:1902960; GO:1903946; GO:1904878 29499 XM_044307434.1 102 67 0 2 36 Q9VFB2 4.16e-35 28S ribosomal protein S10, mitochondrial (MRP-S10) (S10mt) Drosophila melanogaster (Fruit fly) mitochondrial translation [GO:0032543] GO:0003735; GO:0005739; GO:0005763; GO:0032543 29500 XM_044312091.1 130 85 217 46 236 Q99MW1 6.11e-30 Serine/threonine-protein kinase 31 (EC 2.7.11.1) Mus musculus (Mouse) protein phosphorylation [GO:0006468] GO:0001669; GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0006468; GO:0106310 29501 XM_029332244.2 1434 1391 818 1732 1590 NA NA NA NA NA NA 29502 XR_006397349.1 241 515 59 286 465 NA NA NA NA NA NA 29503 XM_029345518.2 3477 1985 1090 2288 1582 P54357 1.72e-30 Myosin-2 essential light chain (Myosin II essential light chain) (Non-muscle myosin essential light chain) Drosophila melanogaster (Fruit fly) actin filament-based movement [GO:0030048] GO:0005509; GO:0005829; GO:0016460; GO:0017022; GO:0030048; GO:0031475; GO:0031476; GO:0031477; GO:0032036 29504 XM_029358371.2 885 1180 540 928 1017 Q5RKJ1 1.35e-148 E3 ubiquitin-protein transferase MAEA (EC 2.3.2.27) (Macrophage erythroblast attacher) Rattus norvegicus (Rat) cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell division [GO:0051301]; cytoskeleton organization [GO:0007010]; enucleate erythrocyte development [GO:0048822]; erythrocyte development [GO:0048821]; erythrocyte maturation [GO:0043249]; negative regulation of myeloid cell apoptotic process [GO:0033033]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] GO:0000151; GO:0003779; GO:0005634; GO:0005654; GO:0005737; GO:0005819; GO:0005826; GO:0005856; GO:0005886; GO:0007010; GO:0007049; GO:0007155; GO:0015629; GO:0016363; GO:0033033; GO:0034657; GO:0043161; GO:0043249; GO:0046872; GO:0048821; GO:0048822; GO:0051301; GO:0061630 29505 XR_003822733.2 10 3 11 5 28 NA NA NA NA NA NA 29506 XM_044316677.1 209 557 300 405 453 Q8R3B7 9.87e-60 Bromodomain-containing protein 8 Mus musculus (Mouse) cellular response to thyroid hormone stimulus [GO:0097067]; chromatin organization [GO:0006325]; histone acetylation [GO:0016573]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of double-strand break repair [GO:2000779] GO:0000786; GO:0000812; GO:0005654; GO:0005739; GO:0006325; GO:0016573; GO:0030374; GO:0035267; GO:0042981; GO:0043967; GO:0043968; GO:0045893; GO:0045944; GO:0046966; GO:0051726; GO:0097067; GO:1905168; GO:2000779 29507 XM_044316677.1 209 557 300 405 453 Q8R3B7 1.13e-38 Bromodomain-containing protein 8 Mus musculus (Mouse) cellular response to thyroid hormone stimulus [GO:0097067]; chromatin organization [GO:0006325]; histone acetylation [GO:0016573]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of double-strand break repair [GO:2000779] GO:0000786; GO:0000812; GO:0005654; GO:0005739; GO:0006325; GO:0016573; GO:0030374; GO:0035267; GO:0042981; GO:0043967; GO:0043968; GO:0045893; GO:0045944; GO:0046966; GO:0051726; GO:0097067; GO:1905168; GO:2000779 29508 XM_029341668.2 1040 0 652 613 0 P23790 9.56e-64 Serum response factor (SRF) Xenopus laevis (African clawed frog) actin cytoskeleton organization [GO:0030036]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000981; GO:0003700; GO:0005634; GO:0010736; GO:0030036; GO:0045944; GO:0046983 29509 XR_006398127.1 0 8 7 4 8 NA NA NA NA NA NA 29510 XR_006397420.1 0 0 0 0 28 NA NA NA NA NA NA 29511 XM_029345801.2 697 141 310 403 202 NA NA NA NA NA NA 29512 XM_044325061.1 1 1 11 0 66 NA NA NA NA NA NA 29513 XM_029328821.2 277 153 91 294 178 P50430 8.87e-156 Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S) Rattus norvegicus (Rat) anterior head development [GO:0097065]; autophagy [GO:0006914]; central nervous system development [GO:0007417]; colon epithelial cell migration [GO:0061580]; dermatan sulfate catabolic process [GO:0030209]; positive regulation of neuron projection development [GO:0010976]; regulation of epithelial cell migration [GO:0010632]; response to estrogen [GO:0043627]; response to methylmercury [GO:0051597]; response to nutrient [GO:0007584]; response to pH [GO:0009268] GO:0003943; GO:0004065; GO:0005739; GO:0005764; GO:0005791; GO:0005794; GO:0006914; GO:0007417; GO:0007584; GO:0008484; GO:0009268; GO:0009986; GO:0010632; GO:0010976; GO:0030209; GO:0043627; GO:0043890; GO:0046872; GO:0051597; GO:0061580; GO:0097065 29514 XM_029349021.2 29 17 50 26 60 NA NA NA NA NA NA 29515 XR_006395297.1 32 18 13 0 24 NA NA NA NA NA NA 29516 XM_044320046.1 39 37 42 36 68 NA NA NA NA NA NA 29517 XM_029330655.2 81 60 68 122 32 Q9XTR8 4.45e-33 Lipase ZK262.3 (EC 3.1.1.-) Caenorhabditis elegans lipid catabolic process [GO:0016042] GO:0005576; GO:0016042; GO:0016787 29518 XR_006391916.1 109 376 2 184 375 NA NA NA NA NA NA 29519 XM_029333718.2 1195 980 933 1453 1323 O43581 1.3e-44 Synaptotagmin-7 (IPCA-7) (Prostate cancer-associated protein 7) (Synaptotagmin VII) (SytVII) Homo sapiens (Human) calcium ion regulated lysosome exocytosis [GO:1990927]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; phagocytosis [GO:0006909]; phagosome-lysosome fusion [GO:0090385]; plasma membrane repair [GO:0001778]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; regulation of bone remodeling [GO:0046850]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of glucagon secretion [GO:0070092]; regulation of insulin secretion [GO:0050796]; regulation of phagocytosis [GO:0050764]; regulation of synaptic vesicle endocytosis [GO:1900242]; short-term synaptic potentiation [GO:1990926]; synaptic vesicle recycling [GO:0036465]; vesicle-mediated cholesterol transport [GO:0090119]; vesicle-mediated transport [GO:0016192] GO:0000149; GO:0001778; GO:0001786; GO:0005509; GO:0005516; GO:0005544; GO:0005546; GO:0005764; GO:0005765; GO:0005777; GO:0005778; GO:0005829; GO:0005886; GO:0006909; GO:0008021; GO:0014059; GO:0016192; GO:0017156; GO:0017158; GO:0019905; GO:0030276; GO:0030670; GO:0030672; GO:0031045; GO:0032009; GO:0036465; GO:0042734; GO:0042995; GO:0045956; GO:0046850; GO:0048791; GO:0050764; GO:0050796; GO:0070062; GO:0070092; GO:0070382; GO:0071277; GO:0090119; GO:0090385; GO:0098686; GO:1900242; GO:1990926; GO:1990927 29520 XM_029352977.2 648 423 537 571 407 P35295 8.86e-39 Ras-related protein Rab-20 Mus musculus (Mouse) cellular response to type II interferon [GO:0071346]; intracellular protein transport [GO:0006886]; phagosome acidification [GO:0090383]; phagosome-lysosome fusion [GO:0090385] GO:0003924; GO:0005525; GO:0005794; GO:0006886; GO:0012505; GO:0030670; GO:0043231; GO:0045335; GO:0071346; GO:0090383; GO:0090385 29521 XR_006395824.1 46 10 16 6 150 NA NA NA NA NA NA 29522 XM_029336766.2 1795 1772 586 978 761 Q8WX92 5.72e-152 Negative elongation factor B (NELF-B) (Cofactor of BRCA1) Homo sapiens (Human) cell population proliferation [GO:0008283]; negative regulation of stem cell differentiation [GO:2000737]; negative regulation of transcription elongation by RNA polymerase II [GO:0034244]; stem cell differentiation [GO:0048863] GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0008283; GO:0032021; GO:0034244; GO:0048863; GO:2000737 29523 XM_044310122.1 605 365 549 954 283 NA NA NA NA NA NA 29524 XM_044323195.1 0 17 3 27 0 O73792 7.6e-53 Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1) Danio rerio (Zebrafish) (Brachydanio rerio) angiogenesis [GO:0001525]; blood vessel development [GO:0001568]; endothelial cell-cell adhesion [GO:0071603]; heart development [GO:0007507]; positive regulation of angiogenesis [GO:0045766]; positive regulation of kinase activity [GO:0033674]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculature development [GO:0001944] GO:0001525; GO:0001568; GO:0001944; GO:0004714; GO:0005524; GO:0005886; GO:0007169; GO:0007507; GO:0033674; GO:0043235; GO:0045766; GO:0071603 29525 XM_029332666.2 0 0 0 29 0 O93309 0 Structural maintenance of chromosomes protein 3 (SMC protein 3) (SMC-3) Xenopus laevis (African clawed frog) cell division [GO:0051301]; chromosome organization [GO:0051276]; DNA repair [GO:0006281]; meiotic cell cycle [GO:0051321]; regulation of DNA replication [GO:0006275] GO:0000775; GO:0000785; GO:0005524; GO:0005634; GO:0006275; GO:0006281; GO:0016887; GO:0030893; GO:0051276; GO:0051301; GO:0051321 29526 XM_029332666.2 0 0 0 29 0 O93309 5.16e-22 Structural maintenance of chromosomes protein 3 (SMC protein 3) (SMC-3) Xenopus laevis (African clawed frog) cell division [GO:0051301]; chromosome organization [GO:0051276]; DNA repair [GO:0006281]; meiotic cell cycle [GO:0051321]; regulation of DNA replication [GO:0006275] GO:0000775; GO:0000785; GO:0005524; GO:0005634; GO:0006275; GO:0006281; GO:0016887; GO:0030893; GO:0051276; GO:0051301; GO:0051321 29527 XM_029340168.2 0 43 0 59 29 NA NA NA NA NA NA 29528 XM_044323487.1 79 70 82 166 0 B7WFQ1 0 Uncharacterized skeletal organic matrix protein 2 (Uncharacterized SOMP-2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29529 XM_044321789.1 328 429 196 197 669 NA NA NA NA NA NA 29530 XR_003825418.2 109 49 7 472 54 NA NA NA NA NA NA 29531 XR_006392137.1 0 0 70 2 173 NA NA NA NA NA NA 29532 XM_044311540.1 0 17 3 31 51 NA NA NA NA NA NA 29533 XM_029330501.2 546 613 584 289 158 NA NA NA NA NA NA 29534 XM_044322476.1 6 123 51 98 139 NA NA NA NA NA NA 29535 XM_044327228.1 452 319 202 392 381 O43264 4.07e-177 Centromere/kinetochore protein zw10 homolog Homo sapiens (Human) cell division [GO:0051301]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; establishment of mitotic spindle orientation [GO:0000132]; Golgi organization [GO:0007030]; meiotic cell cycle [GO:0051321]; mitotic metaphase plate congression [GO:0007080]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint signaling [GO:0007094]; protein localization to kinetochore [GO:0034501]; protein transport [GO:0015031]; protein-containing complex assembly [GO:0065003]; regulation of exit from mitosis [GO:0007096]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] GO:0000070; GO:0000132; GO:0000776; GO:0000922; GO:0005634; GO:0005783; GO:0005789; GO:0005811; GO:0005828; GO:0005829; GO:0006888; GO:0006890; GO:0007030; GO:0007080; GO:0007094; GO:0007096; GO:0015031; GO:0016020; GO:0019237; GO:0034501; GO:0051301; GO:0051321; GO:0065003; GO:0070939; GO:1990423 29536 XM_044325700.1 9 1 19 0 12 NA NA NA NA NA NA 29537 XM_029351808.2 0 48 16 20 41 NA NA NA NA NA NA 29538 XM_029353952.2 61 47 49 52 77 Q6PHG8 6.55e-35 DNA-directed RNA polymerase I subunit RPA43 (DNA-directed RNA polymerase I subunit F) (Twist neighbor protein) Danio rerio (Zebrafish) (Brachydanio rerio) DNA-templated transcription initiation [GO:0006352] GO:0005736; GO:0006352 29539 XM_029346580.2 5680 4393 3949 5458 4815 NA NA NA NA NA NA 29540 XR_006392174.1 0 0 1 0 30 NA NA NA NA NA NA 29541 XM_044307727.1 534 448 268 479 442 Q9D565 1.68e-146 WD repeat-containing protein 64 Mus musculus (Mouse) NA NA 29542 XM_044318927.1 1092 336 817 598 988 Q8VC74 3.76e-55 Cytochrome c oxidase assembly protein COX18, mitochondrial Mus musculus (Mouse) mitochondrial cytochrome c oxidase assembly [GO:0033617]; protein insertion into membrane [GO:0051205]; protein insertion into mitochondrial inner membrane from matrix [GO:0032979]; protein insertion into mitochondrial membrane [GO:0051204]; respiratory chain complex IV assembly [GO:0008535] GO:0005739; GO:0005743; GO:0008535; GO:0032977; GO:0032979; GO:0033617; GO:0051204; GO:0051205 29543 XM_029333803.2 10 0 9 0 12 NA NA NA NA NA NA 29544 XR_006393912.1 41 2 25 5 151 NA NA NA NA NA NA 29545 XM_029345874.2 46 19 33 75 49 Q8UW76 6.6e-110 T-box transcription factor TBX20 (T-box protein 20) (cTbx20) Gallus gallus (Chicken) aortic valve morphogenesis [GO:0003180]; atrial septum morphogenesis [GO:0060413]; atrioventricular canal development [GO:0036302]; blood circulation [GO:0008015]; branching involved in blood vessel morphogenesis [GO:0001569]; cardiac chamber formation [GO:0003207]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac right ventricle morphogenesis [GO:0003215]; cell fate specification [GO:0001708]; cell migration involved in heart development [GO:0060973]; cell proliferation involved in heart valve development [GO:2000793]; dorsal/ventral pattern formation [GO:0009953]; embryonic heart tube elongation [GO:0036306]; endocardial cushion formation [GO:0003272]; foramen ovale closure [GO:0035922]; heart looping [GO:0001947]; mesenchymal cell development [GO:0014031]; motor neuron migration [GO:0097475]; muscle contraction [GO:0006936]; negative regulation of gene expression [GO:0010629]; negative regulation of SMAD protein complex assembly [GO:0010991]; negative regulation of transcription by RNA polymerase II [GO:0000122]; outflow tract septum morphogenesis [GO:0003148]; pericardium morphogenesis [GO:0003344]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell migration [GO:0030335]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of gene expression [GO:0010628]; pulmonary valve formation [GO:0003193]; pulmonary vein morphogenesis [GO:0060577]; regulation of transcription by RNA polymerase II [GO:0006357]; tricuspid valve development [GO:0003175]; vasculogenesis [GO:0001570]; visceral motor neuron differentiation [GO:0021524] GO:0000122; GO:0000978; GO:0000981; GO:0001228; GO:0001569; GO:0001570; GO:0001708; GO:0001947; GO:0003148; GO:0003175; GO:0003180; GO:0003193; GO:0003207; GO:0003215; GO:0003272; GO:0003344; GO:0005634; GO:0005737; GO:0006357; GO:0006936; GO:0008015; GO:0009953; GO:0010628; GO:0010629; GO:0010718; GO:0010991; GO:0014031; GO:0021524; GO:0030335; GO:0030513; GO:0035922; GO:0036302; GO:0036306; GO:0055008; GO:0060045; GO:0060413; GO:0060577; GO:0060973; GO:0061629; GO:0097475; GO:2000793 29546 XM_044312866.1 0 0 0 0 48 Q9GZT4 5.69e-107 Serine racemase (EC 5.1.1.18) (D-serine ammonia-lyase) (D-serine dehydratase) (EC 4.3.1.18) (L-serine ammonia-lyase) (L-serine dehydratase) (EC 4.3.1.17) Homo sapiens (Human) aging [GO:0007568]; brain development [GO:0007420]; D-serine biosynthetic process [GO:0070179]; D-serine metabolic process [GO:0070178]; L-serine metabolic process [GO:0006563]; pyruvate biosynthetic process [GO:0042866]; response to lipopolysaccharide [GO:0032496]; response to morphine [GO:0043278]; response to xenobiotic stimulus [GO:0009410]; serine family amino acid metabolic process [GO:0009069] GO:0000287; GO:0003941; GO:0005509; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006563; GO:0007420; GO:0007568; GO:0008721; GO:0009069; GO:0009410; GO:0016594; GO:0018114; GO:0030165; GO:0030170; GO:0030378; GO:0032496; GO:0042802; GO:0042803; GO:0042866; GO:0043025; GO:0043278; GO:0045177; GO:0070178; GO:0070179 29547 XM_044321579.1 75 18 36 41 49 NA NA NA NA NA NA 29548 XM_044308208.1 455 589 457 654 258 E7FAM5 6.33e-57 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 29549 XM_029347477.2 0 103 8 70 79 NA NA NA NA NA NA 29550 XM_029357672.2 17 7 33 21 43 NA NA NA NA NA NA 29551 XM_029338617.2 0 0 11 110 220 Q2XWK0 1.26e-133 Synaptic vesicle 2-related protein (SV2-related protein) Xenopus laevis (African clawed frog) NA GO:0022857; GO:0030672 29552 XM_044315286.1 14 51 41 8 1 NA NA NA NA NA NA 29553 XM_029325089.2 100 41 76 164 169 NA NA NA NA NA NA 29554 XM_029349276.2 159 77 39 90 99 A2RUV5 0 Probable ATP-dependent DNA helicase HFM1 (EC 3.6.4.12) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cellular component organization or biogenesis [GO:0071840]; meiotic cell cycle [GO:0051321] GO:0003676; GO:0004386; GO:0005524; GO:0016887; GO:0051321; GO:0071840 29555 XM_029329861.2 746 41 287 1002 1895 P20072 1.97e-70 Annexin A7 (Annexin VII) (Annexin-7) (Synexin) Bos taurus (Bovine) NA GO:0005509; GO:0005544; GO:0005634; GO:0005737; GO:0042584 29556 XM_044320101.1 15 8 5 2 56 NA NA NA NA NA NA 29557 XR_006391539.1 16 699 0 14 141 NA NA NA NA NA NA 29558 XM_044315864.1 14 0 15 4 63 NA NA NA NA NA NA 29559 XM_044321778.1 0 0 0 0 111 NA NA NA NA NA NA 29560 XM_029338056.2 144 153 88 194 216 F1LZF0 4.66e-94 Kelch-like protein 2 (Mayven) Rattus norvegicus (Rat) protein ubiquitination [GO:0016567] GO:0001726; GO:0003779; GO:0005737; GO:0005829; GO:0015629; GO:0016567; GO:0030027; GO:0031463; GO:0042802 29561 XM_029347691.2 4 0 3 5 7 NA NA NA NA NA NA 29562 XM_029333738.2 0 0 83 99 0 P11178 4.05e-146 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial (EC 1.2.4.4) (Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain) (BCKDE1A) (BCKDH E1-alpha) Bos taurus (Bovine) branched-chain amino acid catabolic process [GO:0009083] GO:0003863; GO:0005947; GO:0009083; GO:0046872 29563 XM_044309393.1 26 0 10 0 20 NA NA NA NA NA NA 29564 XM_044318380.1 0 0 11 0 5 NA NA NA NA NA NA 29565 XM_044321825.1 203 223 222 222 276 NA NA NA NA NA NA 29566 XM_029345153.2 1584 429 1036 612 478 Q5XK67 3.8e-39 DNA-directed RNA polymerases I and III subunit RPAC2 (RNA polymerases I and III subunit AC2) (AC19) (DNA-directed RNA polymerase I subunit D) Xenopus laevis (African clawed frog) DNA-templated transcription [GO:0006351] GO:0000428; GO:0003677; GO:0003899; GO:0005634; GO:0006351; GO:0046983 29567 XM_029345765.2 367 226 202 286 333 NA NA NA NA NA NA 29568 XM_029357382.2 0 68 43 231 280 A7RFA1 2.87e-163 Phosphotriesterase-related protein (EC 3.1.-.-) (Parathion hydrolase-related protein) Nematostella vectensis (Starlet sea anemone) catabolic process [GO:0009056] GO:0008270; GO:0009056; GO:0016787 29569 XM_044315034.1 0 0 0 5 115 NA NA NA NA NA NA 29570 XM_029335648.2 0 25 0 0 0 Q8N8A2 2.26e-77 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (PP6-ARS-B) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-B) (Ankyrin repeat domain-containing protein 44) Homo sapiens (Human) NA NA 29571 XM_029335648.2 0 25 0 0 0 Q8N8A2 3.63e-70 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (PP6-ARS-B) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-B) (Ankyrin repeat domain-containing protein 44) Homo sapiens (Human) NA NA 29572 XM_029335648.2 0 25 0 0 0 Q8N8A2 9.88e-66 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (PP6-ARS-B) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-B) (Ankyrin repeat domain-containing protein 44) Homo sapiens (Human) NA NA 29573 XM_029335648.2 0 25 0 0 0 Q8N8A2 5.52e-42 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (PP6-ARS-B) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-B) (Ankyrin repeat domain-containing protein 44) Homo sapiens (Human) NA NA 29574 XM_029338676.2 2085 2604 826 1539 1392 NA NA NA NA NA NA 29575 XM_029350118.2 2 0 2 0 33 NA NA NA NA NA NA 29576 XM_029343948.2 350 286 128 475 580 Q8AYK6 1.41e-139 Wee1-like protein kinase 1-A (EC 2.7.10.2) (Zygotic wee1-like protein kinase 2) (XWee2) Xenopus laevis (African clawed frog) cell division [GO:0051301]; mitotic cell cycle [GO:0000278] GO:0000278; GO:0000287; GO:0004715; GO:0005524; GO:0005634; GO:0051301 29577 XM_029341348.2 0 0 5 1 14 NA NA NA NA NA NA 29578 XM_044314003.1 855 610 309 138 124 NA NA NA NA NA NA 29579 XM_029343035.2 25 0 1 20 19 Q2LE78 2.45e-61 BTB/POZ domain-containing protein 6 Xenopus laevis (African clawed frog) NA GO:0005737 29580 XM_044320154.1 0 0 0 0 10 NA NA NA NA NA NA 29581 XM_044326374.1 560 492 379 452 730 Q7TQ20 9.96e-140 DnaJ homolog subfamily C member 2 (Gliosarcoma-related antigen MIDA1) (Zuotin-related factor 1) Rattus norvegicus (Rat) 'de novo' cotranslational protein folding [GO:0051083]; chromatin organization [GO:0006325]; DNA replication [GO:0006260]; negative regulation of cell growth [GO:0030308]; negative regulation of DNA biosynthetic process [GO:2000279]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of translational fidelity [GO:0006450] GO:0003682; GO:0005634; GO:0005730; GO:0005737; GO:0005829; GO:0006260; GO:0006325; GO:0006450; GO:0030308; GO:0030544; GO:0042393; GO:0043022; GO:0045893; GO:0051083; GO:0061649; GO:2000279 29582 XR_006395193.1 43 28 31 16 26 NA NA NA NA NA NA 29583 XM_029330730.2 22915 27136 11614 14924 14379 Q8MJ14 3.44e-71 Glutathione peroxidase 1 (GPx-1) (GSHPx-1) (EC 1.11.1.9) (Cellular glutathione peroxidase) Sus scrofa (Pig) arachidonic acid metabolic process [GO:0019369]; glutathione metabolic process [GO:0006749]; hydrogen peroxide catabolic process [GO:0042744]; lipoxygenase pathway [GO:0019372]; response to hydrogen peroxide [GO:0042542]; response to selenium ion [GO:0010269] GO:0004601; GO:0004602; GO:0005739; GO:0005829; GO:0006749; GO:0010269; GO:0019369; GO:0019372; GO:0042542; GO:0042744; GO:0047066 29584 XM_029327837.2 2 0 0 4 6 NA NA NA NA NA NA 29585 XR_006394081.1 0 0 7 0 0 NA NA NA NA NA NA 29586 XM_044313272.1 13 0 0 22 36 NA NA NA NA NA NA 29587 XM_044326010.1 51 171 45 297 91 Q9UGM3 5.02e-56 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 29588 XM_044326010.1 51 171 45 297 91 Q9UGM3 1.26e-55 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 29589 XM_044326010.1 51 171 45 297 91 Q9UGM3 5.55e-55 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 29590 XM_044326010.1 51 171 45 297 91 Q9UGM3 9.63e-55 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 29591 XM_044326010.1 51 171 45 297 91 Q9UGM3 1.07e-54 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 29592 XM_044326010.1 51 171 45 297 91 Q9UGM3 3.39e-54 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 29593 XM_044326010.1 51 171 45 297 91 Q9UGM3 5.4e-54 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 29594 XM_044326010.1 51 171 45 297 91 Q9UGM3 7.93e-54 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 29595 XM_044326010.1 51 171 45 297 91 Q9UGM3 2.22e-53 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 29596 XM_044326010.1 51 171 45 297 91 Q9UGM3 3.79e-52 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 29597 XM_044326010.1 51 171 45 297 91 Q9UGM3 4.96e-52 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 29598 XM_044326010.1 51 171 45 297 91 Q9UGM3 3.49e-32 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 29599 XM_044326010.1 51 171 45 297 91 Q9UGM3 6.13e-26 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 29600 XM_044326010.1 51 171 45 297 91 Q9UGM3 1.85e-23 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 29601 XM_044326010.1 51 171 45 297 91 Q9UGM3 1.46e-22 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 29602 XR_006396817.1 5 0 3 0 13 NA NA NA NA NA NA 29603 XM_029340615.2 5809 4225 3113 4884 5038 Q92828 2.54e-136 Coronin-2A (IR10) (WD repeat-containing protein 2) Homo sapiens (Human) intracellular signal transduction [GO:0035556] GO:0017053; GO:0035556; GO:0051015 29604 XR_006393016.1 0 0 7 0 10 NA NA NA NA NA NA 29605 XM_044314401.1 100 8 4 37 27 Q96AY4 6.44e-80 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29606 XM_044314401.1 100 8 4 37 27 Q96AY4 2.41e-79 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29607 XM_044314401.1 100 8 4 37 27 Q96AY4 1.09e-77 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29608 XM_044314401.1 100 8 4 37 27 Q96AY4 2.27e-76 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29609 XM_044314401.1 100 8 4 37 27 Q96AY4 8.91e-73 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29610 XM_044314401.1 100 8 4 37 27 Q96AY4 1.08e-66 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29611 XM_044314401.1 100 8 4 37 27 Q96AY4 7.67e-66 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29612 XM_044314401.1 100 8 4 37 27 Q96AY4 1.68e-64 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29613 XM_044314401.1 100 8 4 37 27 Q96AY4 7.98e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29614 XM_044327911.1 0 348 378 0 171 P21956 7.33e-50 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (SED1) (Sperm surface protein SP47) (MP47) Mus musculus (Mouse) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0007155; GO:0007338; GO:0009897; GO:0043277; GO:0062023 29615 XR_006396552.1 8 0 21 7 95 NA NA NA NA NA NA 29616 XM_044321649.1 9 17 10 2 29 C6FG12 6.71e-31 Protein NLRC5 Ictalurus punctatus (Channel catfish) (Silurus punctatus) innate immune response [GO:0045087] GO:0005524; GO:0005737; GO:0045087 29617 XR_006396080.1 4 0 4 31 22 NA NA NA NA NA NA 29618 XM_044325058.1 0 0 15 2 50 NA NA NA NA NA NA 29619 XM_029330973.2 1078 1096 267 1804 864 Q6NYE7 9.76e-35 Transmembrane protein 192 Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005765; GO:0005770 29620 XM_044322419.1 178 142 113 65 218 NA NA NA NA NA NA 29621 XM_044312124.1 2 0 3 0 9 NA NA NA NA NA NA 29622 XM_044327912.1 145 65 87 155 367 NA NA NA NA NA NA 29623 XM_044310694.1 78 70 0 165 67 Q5T890 5.39e-177 DNA excision repair protein ERCC-6-like 2 (EC 3.6.4.-) (DNA repair and recombination protein RAD26-like) Homo sapiens (Human) cellular response to reactive oxygen species [GO:0034614]; interstrand cross-link repair [GO:0036297] GO:0003677; GO:0004386; GO:0005524; GO:0005634; GO:0005737; GO:0005739; GO:0005815; GO:0016787; GO:0019901; GO:0032991; GO:0034614; GO:0036297; GO:0140658 29624 XM_044310694.1 78 70 0 165 67 Q5T890 5.42e-21 DNA excision repair protein ERCC-6-like 2 (EC 3.6.4.-) (DNA repair and recombination protein RAD26-like) Homo sapiens (Human) cellular response to reactive oxygen species [GO:0034614]; interstrand cross-link repair [GO:0036297] GO:0003677; GO:0004386; GO:0005524; GO:0005634; GO:0005737; GO:0005739; GO:0005815; GO:0016787; GO:0019901; GO:0032991; GO:0034614; GO:0036297; GO:0140658 29625 XM_044317293.1 4502 3929 3472 3877 4071 NA NA NA NA NA NA 29626 XM_029334522.2 2071 2220 1342 1620 1246 NA NA NA NA NA NA 29627 XR_006392180.1 17 13 18 34 23 NA NA NA NA NA NA 29628 XM_029333971.2 22 0 1 0 2 NA NA NA NA NA NA 29629 XM_029343285.2 0 10 0 26 0 NA NA NA NA NA NA 29630 XM_029348745.2 281 138 150 207 209 Q5SPX1 3.74e-73 Coiled-coil domain-containing protein 157 Mus musculus (Mouse) NA NA 29631 XR_006391349.1 0 0 0 0 12 NA NA NA NA NA NA 29632 XM_044326311.1 0 97 165 0 398 O60094 4.78e-48 rDNA transcriptional regulator pol5 (DNA polymerase V) (POL V) (DNA polymerase phi) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) regulation of DNA-templated transcription [GO:0006355]; rRNA processing [GO:0006364]; rRNA transcription [GO:0009303] GO:0000166; GO:0000182; GO:0001163; GO:0005634; GO:0005730; GO:0005829; GO:0006355; GO:0006364; GO:0009303 29633 XM_029349106.2 291 543 335 685 425 F6R2G2 5.16e-22 NLR family CARD domain-containing protein 4 (Ice protease-activating factor) (Ipaf) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) apoptotic process [GO:0006915]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; regulation of apoptotic process [GO:0042981] GO:0005524; GO:0005829; GO:0006915; GO:0006954; GO:0042981; GO:0045087 29634 XM_029335446.2 3314 278 1567 531 1282 NA NA NA NA NA NA 29635 XM_029335495.2 5869 7450 2188 3809 5193 Q5ZMH1 4.34e-161 Septin-2 Gallus gallus (Chicken) cilium assembly [GO:0060271]; cytoskeleton-dependent cytokinesis [GO:0061640]; regulation of exocytosis [GO:0017157]; smoothened signaling pathway [GO:0007224] GO:0003924; GO:0005525; GO:0005737; GO:0005819; GO:0005940; GO:0007224; GO:0008021; GO:0015630; GO:0017157; GO:0030496; GO:0031105; GO:0032153; GO:0032154; GO:0060090; GO:0060170; GO:0060271; GO:0061640 29636 XR_006392581.1 23 16 18 19 22 NA NA NA NA NA NA 29637 XM_029350807.2 636 692 662 985 1144 Q924A5 8.46e-101 Proton-coupled amino acid transporter 1 (Proton/amino acid transporter 1) (Lysosomal amino acid transporter 1) (LYAAT-1) (Neutral amino acid/proton symporter) (Solute carrier family 36 member 1) Rattus norvegicus (Rat) alanine transport [GO:0032328]; amino acid import across plasma membrane [GO:0089718]; amino acid transmembrane transport [GO:0003333]; anion transmembrane transport [GO:0098656]; cation transmembrane transport [GO:0098655]; glycine transport [GO:0015816]; L-alanine transport [GO:0015808]; L-alpha-amino acid transmembrane transport [GO:1902475]; L-amino acid transport [GO:0015807]; neutral amino acid transport [GO:0015804]; proline transmembrane transport [GO:0035524]; proline transport [GO:0015824]; proton transmembrane transport [GO:1902600]; taurine transport [GO:0015734] GO:0003333; GO:0005280; GO:0005297; GO:0005368; GO:0005764; GO:0005765; GO:0005783; GO:0005886; GO:0015078; GO:0015175; GO:0015179; GO:0015180; GO:0015187; GO:0015193; GO:0015734; GO:0015804; GO:0015807; GO:0015808; GO:0015816; GO:0015824; GO:0016324; GO:0022858; GO:0032328; GO:0035524; GO:0089718; GO:0098655; GO:0098656; GO:1902475; GO:1902600 29638 XM_029341505.2 48 14 74 84 22 Q5RBE5 6.43e-162 GDP-L-fucose synthase (EC 1.1.1.271) (GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase) (Protein FX) (Red cell NADP(H)-binding protein) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) 'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904906] GO:0010595; GO:0016853; GO:0042351; GO:0050577; GO:1904906 29639 XM_044308578.1 298 434 345 350 266 Q505F5 1.07e-90 Leucine-rich repeat-containing protein 47 Mus musculus (Mouse) phenylalanyl-tRNA aminoacylation [GO:0006432] GO:0003723; GO:0004826; GO:0006432 29640 XM_044328511.1 586 346 432 737 349 C3YWU0 0 Alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucoside fucohydrolase) Branchiostoma floridae (Florida lancelet) (Amphioxus) fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139] GO:0004560; GO:0005576; GO:0005764; GO:0006004; GO:0016139 29641 XM_029326602.2 158 0 0 176 192 Q49LS8 5.97e-28 XK-related protein 6 Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon nigroviridis) NA GO:0005886 29642 XM_044311179.1 0 2 2 0 8 NA NA NA NA NA NA 29643 XM_029346756.2 328 191 68 291 250 NA NA NA NA NA NA 29644 XM_044311180.1 0 5 11 10 0 Q498E6 3.14e-22 N-lysine methyltransferase KMT5A-B (EC 2.1.1.-) (Histone-lysine N-methyltransferase KMT5A-B) (EC 2.1.1.361) (Lysine-specific methylase 5A-B) (Mitotic phosphoprotein 36) (SET domain-containing protein 8-B) Xenopus laevis (African clawed frog) cell cycle [GO:0007049]; cell division [GO:0051301]; chromatin organization [GO:0006325] GO:0005634; GO:0005694; GO:0006325; GO:0007049; GO:0018024; GO:0051301; GO:0140944 29645 XM_029342790.2 37 66 194 7 114 NA NA NA NA NA NA 29646 XM_029350764.2 27 0 0 101 0 P51029 7.26e-72 Protein Wnt-8b Danio rerio (Zebrafish) (Brachydanio rerio) canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; commissural neuron axon guidance [GO:0071679]; embryonic pattern specification [GO:0009880]; eye development [GO:0001654]; eye field cell fate commitment involved in camera-type eye formation [GO:0060898]; forebrain development [GO:0030900]; forebrain neuron differentiation [GO:0021879]; hypothalamus development [GO:0021854]; negative regulation of anterior neural cell fate commitment of the neural plate by Wnt signaling pathway [GO:0022002]; neuron differentiation [GO:0030182]; otic placode formation [GO:0043049]; sensory epithelium regeneration [GO:0070654] GO:0001654; GO:0005109; GO:0005125; GO:0005615; GO:0009880; GO:0021854; GO:0021879; GO:0022002; GO:0030182; GO:0030900; GO:0043049; GO:0045165; GO:0060070; GO:0060898; GO:0070654; GO:0071679 29647 XM_029339673.2 543 508 230 472 423 P20483 1.06e-52 M-phase inducer phosphatase (EC 3.1.3.48) (Cdc25-like protein) (Protein string) Drosophila melanogaster (Fruit fly) cell division [GO:0051301]; centriole replication [GO:0007099]; G2/M transition of mitotic cell cycle [GO:0000086]; gastrulation [GO:0007369]; Golgi organization [GO:0007030]; histoblast morphogenesis [GO:0007488]; negative regulation of cell size [GO:0045792]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of G2/MI transition of meiotic cell cycle [GO:0110032]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of mitotic cell cycle, embryonic [GO:0045977]; protein dephosphorylation [GO:0006470]; regulation of mitotic cell cycle [GO:0007346] GO:0000086; GO:0004725; GO:0005634; GO:0005694; GO:0005737; GO:0006470; GO:0007030; GO:0007099; GO:0007346; GO:0007369; GO:0007488; GO:0008284; GO:0010971; GO:0045792; GO:0045931; GO:0045977; GO:0051301; GO:0110032 29648 XM_044317254.1 20 16 25 20 82 Q80UK0 1.86e-80 SEC14 domain and spectrin repeat-containing protein 1 (Huntingtin-interacting protein-like protein) Mus musculus (Mouse) negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel [GO:1904878] GO:0005546; GO:0010314; GO:0032266; GO:0034704; GO:0043325; GO:0045111; GO:0070273; GO:0070300; GO:0080025; GO:1904878 29649 XM_029331305.2 43 0 31 0 8 Q6DGL2 7.32e-45 NF-kappa-B inhibitor-interacting Ras-like protein 2 (I-kappa-B-interacting Ras-like protein 2) (Kappa B-Ras protein 2) (KappaB-Ras2) Danio rerio (Zebrafish) (Brachydanio rerio) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; Ral protein signal transduction [GO:0032484]; surfactant homeostasis [GO:0043129] GO:0003924; GO:0005525; GO:0005737; GO:0007249; GO:0032484; GO:0032794; GO:0043129 29650 XM_029334465.2 123 188 158 68 97 Q9PVM0 1.41e-27 Homeobox protein otx5-A (Orthodenticle homolog 5-A) (Xotx5) Xenopus laevis (African clawed frog) anterior/posterior pattern specification [GO:0009952]; eye photoreceptor cell fate commitment [GO:0042706]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000981; GO:0003677; GO:0005634; GO:0009952; GO:0042706; GO:0045944 29651 XR_006396352.1 0 1 0 0 21 NA NA NA NA NA NA 29652 XM_044319080.1 83 330 45 98 195 Q9QZ85 5.39e-52 Interferon-inducible GTPase 1 (EC 3.6.5.-) Mus musculus (Mouse) cellular response to interferon-beta [GO:0035458]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; regulation of autophagy [GO:0010506]; response to bacterium [GO:0009617] GO:0003924; GO:0005525; GO:0005737; GO:0005789; GO:0006952; GO:0009617; GO:0010506; GO:0019003; GO:0019221; GO:0020005; GO:0031965; GO:0032580; GO:0035458; GO:0042802; GO:0042832; GO:0045087; GO:0050829 29653 XM_029331639.2 67 21 66 39 43 NA NA NA NA NA NA 29654 XR_006391583.1 0 0 0 64 0 NA NA NA NA NA NA 29655 XM_029343208.2 619 522 295 503 538 Q9Z142 1.05e-73 Transmembrane protein 33 (Protein DB83) Rattus norvegicus (Rat) endoplasmic reticulum tubular network organization [GO:0071786]; innate immune response [GO:0045087]; membrane organization [GO:0061024]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of PERK-mediated unfolded protein response [GO:1903899]; regulation of endoplasmic reticulum tubular network organization [GO:1903371]; response to endoplasmic reticulum stress [GO:0034976] GO:0005635; GO:0005783; GO:0005789; GO:0034976; GO:0042470; GO:0045087; GO:0061024; GO:0071786; GO:1903371; GO:1903896; GO:1903899 29656 XM_029333303.2 4 6 7 11 35 P63142 3.65e-87 Potassium voltage-gated channel subfamily A member 2 (RAK) (RBK2) (RCK5) (Voltage-gated potassium channel subunit Kv1.2) Rattus norvegicus (Rat) cerebral cortex development [GO:0021987]; corpus callosum development [GO:0022038]; neuronal action potential [GO:0019228]; optic nerve development [GO:0021554]; optic nerve structural organization [GO:0021633]; potassium ion export across plasma membrane [GO:0097623]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233] GO:0005249; GO:0005251; GO:0005768; GO:0005789; GO:0005886; GO:0008076; GO:0014059; GO:0015271; GO:0016020; GO:0019228; GO:0019233; GO:0019894; GO:0021554; GO:0021633; GO:0021987; GO:0022038; GO:0030027; GO:0030424; GO:0030425; GO:0031258; GO:0032809; GO:0033010; GO:0034705; GO:0034765; GO:0042734; GO:0043194; GO:0043204; GO:0043679; GO:0044224; GO:0044305; GO:0045188; GO:0045211; GO:0051260; GO:0071805; GO:0097623; GO:0098978; GO:0099508; GO:1905030 29657 XM_029330367.2 81 23 7 0 7 O42357 9.45e-25 Retinal homeobox protein Rx2 Danio rerio (Zebrafish) (Brachydanio rerio) camera-type eye photoreceptor cell differentiation [GO:0060219]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0045944; GO:0060219 29658 XR_006392147.1 6 0 2 8 0 NA NA NA NA NA NA 29659 XR_006398014.1 29 16 13 5 100 NA NA NA NA NA NA 29660 XM_044327204.1 1128 988 551 827 1034 NA NA NA NA NA NA 29661 XM_029337345.2 2896 3721 2623 5873 4632 P49744 0 Thrombospondin-4 Rattus norvegicus (Rat) behavioral response to pain [GO:0048266]; endothelial cell-cell adhesion [GO:0071603]; myoblast migration [GO:0051451]; negative regulation of angiogenesis [GO:0016525]; nervous system development [GO:0007399]; neuron projection morphogenesis [GO:0048812]; positive regulation of cell division [GO:0051781]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of tissue remodeling [GO:0034103]; response to endoplasmic reticulum stress [GO:0034976]; response to unfolded protein [GO:0006986]; tissue remodeling [GO:0048771] GO:0001938; GO:0001968; GO:0005178; GO:0005509; GO:0005518; GO:0005604; GO:0005615; GO:0005783; GO:0006986; GO:0007399; GO:0008083; GO:0008201; GO:0016525; GO:0016529; GO:0031012; GO:0031594; GO:0034103; GO:0034976; GO:0042802; GO:0043237; GO:0048266; GO:0048771; GO:0048812; GO:0050731; GO:0051451; GO:0051781; GO:0062023; GO:0071603; GO:0090023 29662 XR_006392023.1 0 0 0 7 5 NA NA NA NA NA NA 29663 XM_044309447.1 4 4 9 0 46 Q15485 1.16e-81 Ficolin-2 (37 kDa elastin-binding protein) (Collagen/fibrinogen domain-containing protein 2) (EBP-37) (Ficolin-B) (Ficolin-beta) (Hucolin) (L-ficolin) (Serum lectin p35) Homo sapiens (Human) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; positive regulation of opsonization [GO:1903028]; proteolysis [GO:0006508]; recognition of apoptotic cell [GO:0043654] GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005576; GO:0005581; GO:0005615; GO:0006508; GO:0008228; GO:0009897; GO:0042802; GO:0043394; GO:0043654; GO:0046872; GO:0048306; GO:0050829; GO:0050830; GO:0062023; GO:0070062; GO:0072562; GO:0097367; GO:1903028; GO:1905370; GO:2001065 29664 XR_006394826.1 32 0 0 0 0 NA NA NA NA NA NA 29665 XR_003825417.2 89 55 39 45 110 NA NA NA NA NA NA 29666 XM_044320397.1 119 45 222 121 892 NA NA NA NA NA NA 29667 XM_029342842.2 709 572 359 772 676 Q9NYI0 5.49e-94 PH and SEC7 domain-containing protein 3 (Epididymis tissue protein Li 20mP) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 D) (Exchange factor for ARF6 D) (Hepatocellular carcinoma-associated antigen 67) (Pleckstrin homology and SEC7 domain-containing protein 3) Homo sapiens (Human) regulation of ARF protein signal transduction [GO:0032012] GO:0005085; GO:0014069; GO:0032012; GO:0032587 29668 XM_029323453.2 22 0 0 0 0 Q8CHN8 3.85e-36 Mannan-binding lectin serine protease 1 (EC 3.4.21.-) (Complement factor MASP-3) (Complement-activating component of Ra-reactive factor) (Mannose-binding lectin-associated serine protease 1) (MASP-1) (Mannose-binding protein-associated serine protease) (Ra-reactive factor serine protease p100) (RaRF) (Serine protease 5) [Cleaved into: Mannan-binding lectin serine protease 1 heavy chain; Mannan-binding lectin serine protease 1 light chain] Rattus norvegicus (Rat) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; positive regulation of opsonization [GO:1903028]; proteolysis [GO:0006508] GO:0001867; GO:0002752; GO:0004252; GO:0005509; GO:0005615; GO:0006508; GO:0006956; GO:0008233; GO:0042803; GO:0048306; GO:1903028; GO:1905370 29669 XM_044321807.1 0 0 21 34 100 NA NA NA NA NA NA 29670 XM_044324682.1 50 597 388 157 267 Q8C0W1 1.8e-61 Ankyrin repeat and MYND domain-containing protein 1 Mus musculus (Mouse) NA GO:0046872 29671 XM_044324682.1 50 597 388 157 267 Q8C0W1 1.45e-22 Ankyrin repeat and MYND domain-containing protein 1 Mus musculus (Mouse) NA GO:0046872 29672 XM_029351377.2 70 29 19 67 69 Q4HX89 5.89e-23 Protein BTN1 Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1) (Wheat head blight fungus) (Fusarium graminearum) amino acid transport [GO:0006865] GO:0005774; GO:0006865 29673 XM_044323567.1 17 1 0 0 81 NA NA NA NA NA NA 29674 XM_029354411.2 146 65 84 85 164 Q6DHN0 1.27e-31 Transmembrane protein 53 Danio rerio (Zebrafish) (Brachydanio rerio) negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of ossification [GO:0030279]; negative regulation of osteoblast differentiation [GO:0045668]; regulation of nucleocytoplasmic transport [GO:0046822] GO:0005640; GO:0030279; GO:0030514; GO:0031965; GO:0045668; GO:0046822 29675 XM_044322820.1 25 23 20 36 41 Q6ZSS7 1.05e-37 Major facilitator superfamily domain-containing protein 6 (Macrophage MHC class I receptor 2 homolog) Homo sapiens (Human) antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590] GO:0005886; GO:0016020; GO:0042590 29676 XM_044312248.1 13 0 14 8 19 NA NA NA NA NA NA 29677 XM_044309512.1 0 1 8 0 0 NA NA NA NA NA NA 29678 XM_029347240.2 8811 13765 3069 3555 6689 P62861 6.52e-52 FAU ubiquitin-like and ribosomal protein S30 [Cleaved into: Ubiquitin-like protein FUBI; 40S ribosomal protein S30 (Small ribosomal subunit protein eS30)] Homo sapiens (Human) antibacterial humoral response [GO:0019731]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cytoplasmic translation [GO:0002181]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response in mucosa [GO:0002227]; ribosomal small subunit assembly [GO:0000028]; translation [GO:0006412] GO:0000028; GO:0002181; GO:0002227; GO:0003723; GO:0003735; GO:0005615; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006412; GO:0015935; GO:0019731; GO:0022626; GO:0022627; GO:0050830; GO:0061844 29679 XM_044317237.1 0 0 0 0 11 NA NA NA NA NA NA 29680 XM_044315801.1 9 0 3 4 0 NA NA NA NA NA NA 29681 XM_029334821.2 104 66 39 115 69 NA NA NA NA NA NA 29682 XR_006394435.1 33 1 45 119 79 NA NA NA NA NA NA 29683 XM_029327873.2 4 0 0 0 7 NA NA NA NA NA NA 29684 XM_044309233.1 159 154 50 47 214 Q6P9N1 1.97e-43 Hyccin (Down-regulated by CTNNB1 protein A) Mus musculus (Mouse) myelination [GO:0042552]; phosphatidylinositol phosphate biosynthetic process [GO:0046854]; protein localization to plasma membrane [GO:0072659] GO:0005737; GO:0005829; GO:0005886; GO:0042552; GO:0043005; GO:0046854; GO:0072659 29685 XM_044327272.1 1358 905 1015 1920 2458 Q91ZX7 0 Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)] Mus musculus (Mouse) amyloid-beta clearance [GO:0097242]; amyloid-beta clearance by cellular catabolic process [GO:0150094]; amyloid-beta clearance by transcytosis [GO:0150093]; aorta morphogenesis [GO:0035909]; apoptotic cell clearance [GO:0043277]; astrocyte activation involved in immune response [GO:0002265]; cardiac septum development [GO:0003279]; cell population proliferation [GO:0008283]; cellular lipid catabolic process [GO:0044242]; cellular response to amyloid-beta [GO:1904646]; chemoattraction of axon [GO:0061642]; cholesterol metabolic process [GO:0008203]; coronary vasculature development [GO:0060976]; enzyme-linked receptor protein signaling pathway [GO:0007167]; lysosomal transport [GO:0007041]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of gene expression [GO:0010629]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron projection development [GO:0010977]; negative regulation of pathway-restricted SMAD protein phosphorylation [GO:0060394]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of SMAD protein signal transduction [GO:0060392]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of Wnt signaling pathway [GO:0030178]; phagocytosis [GO:0006909]; positive regulation of amyloid-beta clearance [GO:1900223]; positive regulation of axon extension [GO:0045773]; positive regulation of axon extension involved in regeneration [GO:0048691]; positive regulation of cell death [GO:0010942]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of cholesterol import [GO:1904109]; positive regulation of cholesterol transport [GO:0032376]; positive regulation of collateral sprouting of injured axon [GO:0048694]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of endocytosis [GO:0045807]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of lipid transport [GO:0032370]; positive regulation of lysosomal protein catabolic process [GO:1905167]; positive regulation of neuron projection development [GO:0010976]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein transport [GO:0051222]; positive regulation of Schwann cell migration [GO:1900149]; positive regulation of transcytosis [GO:1904300]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cholesterol transport [GO:0032374]; regulation of phospholipase A2 activity [GO:0032429]; regulation of pulmonary blood vessel remodeling [GO:1905109]; transport across blood-brain barrier [GO:0150104] GO:0002020; GO:0002265; GO:0003279; GO:0005102; GO:0005509; GO:0005634; GO:0005768; GO:0005769; GO:0005794; GO:0005856; GO:0005886; GO:0005905; GO:0006898; GO:0006909; GO:0007041; GO:0007167; GO:0007204; GO:0007205; GO:0008203; GO:0008283; GO:0009897; GO:0010629; GO:0010812; GO:0010875; GO:0010942; GO:0010976; GO:0010977; GO:0014912; GO:0015026; GO:0016020; GO:0016323; GO:0016964; GO:0030136; GO:0030178; GO:0030425; GO:0030512; GO:0031623; GO:0032050; GO:0032092; GO:0032370; GO:0032374; GO:0032376; GO:0032429; GO:0032593; GO:0032956; GO:0034185; GO:0035774; GO:0035909; GO:0038024; GO:0043025; GO:0043066; GO:0043235; GO:0043277; GO:0043524; GO:0044242; GO:0044295; GO:0044877; GO:0045177; GO:0045773; GO:0045807; GO:0048691; GO:0048694; GO:0050766; GO:0051222; GO:0051481; GO:0051895; GO:0060392; GO:0060394; GO:0060548; GO:0060976; GO:0061642; GO:0062136; GO:0070374; GO:0097242; GO:0150093; GO:0150094; GO:0150104; GO:1900149; GO:1900223; GO:1903078; GO:1904109; GO:1904300; GO:1904646; GO:1904754; GO:1905109; GO:1905167; GO:2000343; GO:2000587 29686 XM_044327272.1 1358 905 1015 1920 2458 Q91ZX7 0 Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)] Mus musculus (Mouse) amyloid-beta clearance [GO:0097242]; amyloid-beta clearance by cellular catabolic process [GO:0150094]; amyloid-beta clearance by transcytosis [GO:0150093]; aorta morphogenesis [GO:0035909]; apoptotic cell clearance [GO:0043277]; astrocyte activation involved in immune response [GO:0002265]; cardiac septum development [GO:0003279]; cell population proliferation [GO:0008283]; cellular lipid catabolic process [GO:0044242]; cellular response to amyloid-beta [GO:1904646]; chemoattraction of axon [GO:0061642]; cholesterol metabolic process [GO:0008203]; coronary vasculature development [GO:0060976]; enzyme-linked receptor protein signaling pathway [GO:0007167]; lysosomal transport [GO:0007041]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of gene expression [GO:0010629]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron projection development [GO:0010977]; negative regulation of pathway-restricted SMAD protein phosphorylation [GO:0060394]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of SMAD protein signal transduction [GO:0060392]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of Wnt signaling pathway [GO:0030178]; phagocytosis [GO:0006909]; positive regulation of amyloid-beta clearance [GO:1900223]; positive regulation of axon extension [GO:0045773]; positive regulation of axon extension involved in regeneration [GO:0048691]; positive regulation of cell death [GO:0010942]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of cholesterol import [GO:1904109]; positive regulation of cholesterol transport [GO:0032376]; positive regulation of collateral sprouting of injured axon [GO:0048694]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of endocytosis [GO:0045807]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of lipid transport [GO:0032370]; positive regulation of lysosomal protein catabolic process [GO:1905167]; positive regulation of neuron projection development [GO:0010976]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein transport [GO:0051222]; positive regulation of Schwann cell migration [GO:1900149]; positive regulation of transcytosis [GO:1904300]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cholesterol transport [GO:0032374]; regulation of phospholipase A2 activity [GO:0032429]; regulation of pulmonary blood vessel remodeling [GO:1905109]; transport across blood-brain barrier [GO:0150104] GO:0002020; GO:0002265; GO:0003279; GO:0005102; GO:0005509; GO:0005634; GO:0005768; GO:0005769; GO:0005794; GO:0005856; GO:0005886; GO:0005905; GO:0006898; GO:0006909; GO:0007041; GO:0007167; GO:0007204; GO:0007205; GO:0008203; GO:0008283; GO:0009897; GO:0010629; GO:0010812; GO:0010875; GO:0010942; GO:0010976; GO:0010977; GO:0014912; GO:0015026; GO:0016020; GO:0016323; GO:0016964; GO:0030136; GO:0030178; GO:0030425; GO:0030512; GO:0031623; GO:0032050; GO:0032092; GO:0032370; GO:0032374; GO:0032376; GO:0032429; GO:0032593; GO:0032956; GO:0034185; GO:0035774; GO:0035909; GO:0038024; GO:0043025; GO:0043066; GO:0043235; GO:0043277; GO:0043524; GO:0044242; GO:0044295; GO:0044877; GO:0045177; GO:0045773; GO:0045807; GO:0048691; GO:0048694; GO:0050766; GO:0051222; GO:0051481; GO:0051895; GO:0060392; GO:0060394; GO:0060548; GO:0060976; GO:0061642; GO:0062136; GO:0070374; GO:0097242; GO:0150093; GO:0150094; GO:0150104; GO:1900149; GO:1900223; GO:1903078; GO:1904109; GO:1904300; GO:1904646; GO:1904754; GO:1905109; GO:1905167; GO:2000343; GO:2000587 29687 XM_044327272.1 1358 905 1015 1920 2458 Q91ZX7 4.54e-114 Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)] Mus musculus (Mouse) amyloid-beta clearance [GO:0097242]; amyloid-beta clearance by cellular catabolic process [GO:0150094]; amyloid-beta clearance by transcytosis [GO:0150093]; aorta morphogenesis [GO:0035909]; apoptotic cell clearance [GO:0043277]; astrocyte activation involved in immune response [GO:0002265]; cardiac septum development [GO:0003279]; cell population proliferation [GO:0008283]; cellular lipid catabolic process [GO:0044242]; cellular response to amyloid-beta [GO:1904646]; chemoattraction of axon [GO:0061642]; cholesterol metabolic process [GO:0008203]; coronary vasculature development [GO:0060976]; enzyme-linked receptor protein signaling pathway [GO:0007167]; lysosomal transport [GO:0007041]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of gene expression [GO:0010629]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron projection development [GO:0010977]; negative regulation of pathway-restricted SMAD protein phosphorylation [GO:0060394]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of SMAD protein signal transduction [GO:0060392]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of Wnt signaling pathway [GO:0030178]; phagocytosis [GO:0006909]; positive regulation of amyloid-beta clearance [GO:1900223]; positive regulation of axon extension [GO:0045773]; positive regulation of axon extension involved in regeneration [GO:0048691]; positive regulation of cell death [GO:0010942]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of cholesterol import [GO:1904109]; positive regulation of cholesterol transport [GO:0032376]; positive regulation of collateral sprouting of injured axon [GO:0048694]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of endocytosis [GO:0045807]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of lipid transport [GO:0032370]; positive regulation of lysosomal protein catabolic process [GO:1905167]; positive regulation of neuron projection development [GO:0010976]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein transport [GO:0051222]; positive regulation of Schwann cell migration [GO:1900149]; positive regulation of transcytosis [GO:1904300]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cholesterol transport [GO:0032374]; regulation of phospholipase A2 activity [GO:0032429]; regulation of pulmonary blood vessel remodeling [GO:1905109]; transport across blood-brain barrier [GO:0150104] GO:0002020; GO:0002265; GO:0003279; GO:0005102; GO:0005509; GO:0005634; GO:0005768; GO:0005769; GO:0005794; GO:0005856; GO:0005886; GO:0005905; GO:0006898; GO:0006909; GO:0007041; GO:0007167; GO:0007204; GO:0007205; GO:0008203; GO:0008283; GO:0009897; GO:0010629; GO:0010812; GO:0010875; GO:0010942; GO:0010976; GO:0010977; GO:0014912; GO:0015026; GO:0016020; GO:0016323; GO:0016964; GO:0030136; GO:0030178; GO:0030425; GO:0030512; GO:0031623; GO:0032050; GO:0032092; GO:0032370; GO:0032374; GO:0032376; GO:0032429; GO:0032593; GO:0032956; GO:0034185; GO:0035774; GO:0035909; GO:0038024; GO:0043025; GO:0043066; GO:0043235; GO:0043277; GO:0043524; GO:0044242; GO:0044295; GO:0044877; GO:0045177; GO:0045773; GO:0045807; GO:0048691; GO:0048694; GO:0050766; GO:0051222; GO:0051481; GO:0051895; GO:0060392; GO:0060394; GO:0060548; GO:0060976; GO:0061642; GO:0062136; GO:0070374; GO:0097242; GO:0150093; GO:0150094; GO:0150104; GO:1900149; GO:1900223; GO:1903078; GO:1904109; GO:1904300; GO:1904646; GO:1904754; GO:1905109; GO:1905167; GO:2000343; GO:2000587 29688 XM_044327272.1 1358 905 1015 1920 2458 Q91ZX7 2.68e-112 Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)] Mus musculus (Mouse) amyloid-beta clearance [GO:0097242]; amyloid-beta clearance by cellular catabolic process [GO:0150094]; amyloid-beta clearance by transcytosis [GO:0150093]; aorta morphogenesis [GO:0035909]; apoptotic cell clearance [GO:0043277]; astrocyte activation involved in immune response [GO:0002265]; cardiac septum development [GO:0003279]; cell population proliferation [GO:0008283]; cellular lipid catabolic process [GO:0044242]; cellular response to amyloid-beta [GO:1904646]; chemoattraction of axon [GO:0061642]; cholesterol metabolic process [GO:0008203]; coronary vasculature development [GO:0060976]; enzyme-linked receptor protein signaling pathway [GO:0007167]; lysosomal transport [GO:0007041]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of gene expression [GO:0010629]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron projection development [GO:0010977]; negative regulation of pathway-restricted SMAD protein phosphorylation [GO:0060394]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of SMAD protein signal transduction [GO:0060392]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of Wnt signaling pathway [GO:0030178]; phagocytosis [GO:0006909]; positive regulation of amyloid-beta clearance [GO:1900223]; positive regulation of axon extension [GO:0045773]; positive regulation of axon extension involved in regeneration [GO:0048691]; positive regulation of cell death [GO:0010942]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of cholesterol import [GO:1904109]; positive regulation of cholesterol transport [GO:0032376]; positive regulation of collateral sprouting of injured axon [GO:0048694]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of endocytosis [GO:0045807]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of lipid transport [GO:0032370]; positive regulation of lysosomal protein catabolic process [GO:1905167]; positive regulation of neuron projection development [GO:0010976]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein transport [GO:0051222]; positive regulation of Schwann cell migration [GO:1900149]; positive regulation of transcytosis [GO:1904300]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cholesterol transport [GO:0032374]; regulation of phospholipase A2 activity [GO:0032429]; regulation of pulmonary blood vessel remodeling [GO:1905109]; transport across blood-brain barrier [GO:0150104] GO:0002020; GO:0002265; GO:0003279; GO:0005102; GO:0005509; GO:0005634; GO:0005768; GO:0005769; GO:0005794; GO:0005856; GO:0005886; GO:0005905; GO:0006898; GO:0006909; GO:0007041; GO:0007167; GO:0007204; GO:0007205; GO:0008203; GO:0008283; GO:0009897; GO:0010629; GO:0010812; GO:0010875; GO:0010942; GO:0010976; GO:0010977; GO:0014912; GO:0015026; GO:0016020; GO:0016323; GO:0016964; GO:0030136; GO:0030178; GO:0030425; GO:0030512; GO:0031623; GO:0032050; GO:0032092; GO:0032370; GO:0032374; GO:0032376; GO:0032429; GO:0032593; GO:0032956; GO:0034185; GO:0035774; GO:0035909; GO:0038024; GO:0043025; GO:0043066; GO:0043235; GO:0043277; GO:0043524; GO:0044242; GO:0044295; GO:0044877; GO:0045177; GO:0045773; GO:0045807; GO:0048691; GO:0048694; GO:0050766; GO:0051222; GO:0051481; GO:0051895; GO:0060392; GO:0060394; GO:0060548; GO:0060976; GO:0061642; GO:0062136; GO:0070374; GO:0097242; GO:0150093; GO:0150094; GO:0150104; GO:1900149; GO:1900223; GO:1903078; GO:1904109; GO:1904300; GO:1904646; GO:1904754; GO:1905109; GO:1905167; GO:2000343; GO:2000587 29689 XM_044327272.1 1358 905 1015 1920 2458 Q91ZX7 2.35e-44 Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)] Mus musculus (Mouse) amyloid-beta clearance [GO:0097242]; amyloid-beta clearance by cellular catabolic process [GO:0150094]; amyloid-beta clearance by transcytosis [GO:0150093]; aorta morphogenesis [GO:0035909]; apoptotic cell clearance [GO:0043277]; astrocyte activation involved in immune response [GO:0002265]; cardiac septum development [GO:0003279]; cell population proliferation [GO:0008283]; cellular lipid catabolic process [GO:0044242]; cellular response to amyloid-beta [GO:1904646]; chemoattraction of axon [GO:0061642]; cholesterol metabolic process [GO:0008203]; coronary vasculature development [GO:0060976]; enzyme-linked receptor protein signaling pathway [GO:0007167]; lysosomal transport [GO:0007041]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of gene expression [GO:0010629]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron projection development [GO:0010977]; negative regulation of pathway-restricted SMAD protein phosphorylation [GO:0060394]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of SMAD protein signal transduction [GO:0060392]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of Wnt signaling pathway [GO:0030178]; phagocytosis [GO:0006909]; positive regulation of amyloid-beta clearance [GO:1900223]; positive regulation of axon extension [GO:0045773]; positive regulation of axon extension involved in regeneration [GO:0048691]; positive regulation of cell death [GO:0010942]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of cholesterol import [GO:1904109]; positive regulation of cholesterol transport [GO:0032376]; positive regulation of collateral sprouting of injured axon [GO:0048694]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of endocytosis [GO:0045807]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of lipid transport [GO:0032370]; positive regulation of lysosomal protein catabolic process [GO:1905167]; positive regulation of neuron projection development [GO:0010976]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein transport [GO:0051222]; positive regulation of Schwann cell migration [GO:1900149]; positive regulation of transcytosis [GO:1904300]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cholesterol transport [GO:0032374]; regulation of phospholipase A2 activity [GO:0032429]; regulation of pulmonary blood vessel remodeling [GO:1905109]; transport across blood-brain barrier [GO:0150104] GO:0002020; GO:0002265; GO:0003279; GO:0005102; GO:0005509; GO:0005634; GO:0005768; GO:0005769; GO:0005794; GO:0005856; GO:0005886; GO:0005905; GO:0006898; GO:0006909; GO:0007041; GO:0007167; GO:0007204; GO:0007205; GO:0008203; GO:0008283; GO:0009897; GO:0010629; GO:0010812; GO:0010875; GO:0010942; GO:0010976; GO:0010977; GO:0014912; GO:0015026; GO:0016020; GO:0016323; GO:0016964; GO:0030136; GO:0030178; GO:0030425; GO:0030512; GO:0031623; GO:0032050; GO:0032092; GO:0032370; GO:0032374; GO:0032376; GO:0032429; GO:0032593; GO:0032956; GO:0034185; GO:0035774; GO:0035909; GO:0038024; GO:0043025; GO:0043066; GO:0043235; GO:0043277; GO:0043524; GO:0044242; GO:0044295; GO:0044877; GO:0045177; GO:0045773; GO:0045807; GO:0048691; GO:0048694; GO:0050766; GO:0051222; GO:0051481; GO:0051895; GO:0060392; GO:0060394; GO:0060548; GO:0060976; GO:0061642; GO:0062136; GO:0070374; GO:0097242; GO:0150093; GO:0150094; GO:0150104; GO:1900149; GO:1900223; GO:1903078; GO:1904109; GO:1904300; GO:1904646; GO:1904754; GO:1905109; GO:1905167; GO:2000343; GO:2000587 29690 XM_044327272.1 1358 905 1015 1920 2458 Q91ZX7 6.48e-44 Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)] Mus musculus (Mouse) amyloid-beta clearance [GO:0097242]; amyloid-beta clearance by cellular catabolic process [GO:0150094]; amyloid-beta clearance by transcytosis [GO:0150093]; aorta morphogenesis [GO:0035909]; apoptotic cell clearance [GO:0043277]; astrocyte activation involved in immune response [GO:0002265]; cardiac septum development [GO:0003279]; cell population proliferation [GO:0008283]; cellular lipid catabolic process [GO:0044242]; cellular response to amyloid-beta [GO:1904646]; chemoattraction of axon [GO:0061642]; cholesterol metabolic process [GO:0008203]; coronary vasculature development [GO:0060976]; enzyme-linked receptor protein signaling pathway [GO:0007167]; lysosomal transport [GO:0007041]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of gene expression [GO:0010629]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron projection development [GO:0010977]; negative regulation of pathway-restricted SMAD protein phosphorylation [GO:0060394]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of SMAD protein signal transduction [GO:0060392]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of Wnt signaling pathway [GO:0030178]; phagocytosis [GO:0006909]; positive regulation of amyloid-beta clearance [GO:1900223]; positive regulation of axon extension [GO:0045773]; positive regulation of axon extension involved in regeneration [GO:0048691]; positive regulation of cell death [GO:0010942]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of cholesterol import [GO:1904109]; positive regulation of cholesterol transport [GO:0032376]; positive regulation of collateral sprouting of injured axon [GO:0048694]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of endocytosis [GO:0045807]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of lipid transport [GO:0032370]; positive regulation of lysosomal protein catabolic process [GO:1905167]; positive regulation of neuron projection development [GO:0010976]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein transport [GO:0051222]; positive regulation of Schwann cell migration [GO:1900149]; positive regulation of transcytosis [GO:1904300]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cholesterol transport [GO:0032374]; regulation of phospholipase A2 activity [GO:0032429]; regulation of pulmonary blood vessel remodeling [GO:1905109]; transport across blood-brain barrier [GO:0150104] GO:0002020; GO:0002265; GO:0003279; GO:0005102; GO:0005509; GO:0005634; GO:0005768; GO:0005769; GO:0005794; GO:0005856; GO:0005886; GO:0005905; GO:0006898; GO:0006909; GO:0007041; GO:0007167; GO:0007204; GO:0007205; GO:0008203; GO:0008283; GO:0009897; GO:0010629; GO:0010812; GO:0010875; GO:0010942; GO:0010976; GO:0010977; GO:0014912; GO:0015026; GO:0016020; GO:0016323; GO:0016964; GO:0030136; GO:0030178; GO:0030425; GO:0030512; GO:0031623; GO:0032050; GO:0032092; GO:0032370; GO:0032374; GO:0032376; GO:0032429; GO:0032593; GO:0032956; GO:0034185; GO:0035774; GO:0035909; GO:0038024; GO:0043025; GO:0043066; GO:0043235; GO:0043277; GO:0043524; GO:0044242; GO:0044295; GO:0044877; GO:0045177; GO:0045773; GO:0045807; GO:0048691; GO:0048694; GO:0050766; GO:0051222; GO:0051481; GO:0051895; GO:0060392; GO:0060394; GO:0060548; GO:0060976; GO:0061642; GO:0062136; GO:0070374; GO:0097242; GO:0150093; GO:0150094; GO:0150104; GO:1900149; GO:1900223; GO:1903078; GO:1904109; GO:1904300; GO:1904646; GO:1904754; GO:1905109; GO:1905167; GO:2000343; GO:2000587 29691 XM_029330049.2 125 92 58 199 117 Q68FQ7 4.12e-74 RNA polymerase II-associated protein 3 Rattus norvegicus (Rat) NA GO:0097255; GO:0101031; GO:1990062 29692 XM_029330049.2 125 92 58 199 117 Q68FQ7 6.71e-44 RNA polymerase II-associated protein 3 Rattus norvegicus (Rat) NA GO:0097255; GO:0101031; GO:1990062 29693 XM_029347913.2 101 15 44 6 13 NA NA NA NA NA NA 29694 XM_044312731.1 563 38 435 79 460 Q66HG5 0 Transmembrane 9 superfamily member 2 Rattus norvegicus (Rat) ceramide metabolic process [GO:0006672]; glycosphingolipid biosynthetic process [GO:0006688]; protein localization to membrane [GO:0072657]; regulation of heparan sulfate proteoglycan biosynthetic process [GO:0010908] GO:0005794; GO:0005856; GO:0006672; GO:0006688; GO:0010008; GO:0010908; GO:0016020; GO:0072657 29695 XM_029338015.2 27 9 5 49 6 NA NA NA NA NA NA 29696 XM_029347784.2 467 351 306 383 406 P33611 3.28e-144 DNA polymerase alpha subunit B (DNA polymerase alpha 70 kDa subunit) Mus musculus (Mouse) DNA replication [GO:0006260]; DNA replication initiation [GO:0006270]; DNA replication, synthesis of RNA primer [GO:0006269]; protein import into nucleus [GO:0006606] GO:0003677; GO:0003887; GO:0005634; GO:0005654; GO:0005658; GO:0005829; GO:0006260; GO:0006269; GO:0006270; GO:0006606 29697 XM_044316090.1 68 0 150 252 144 P41247 3.44e-75 Patatin-like phospholipase domain-containing protein 4 (EC 3.1.1.3) (Calcium-independent phospholipase A2-eta) (iPLA2-eta) (EC 3.1.1.4) (Protein GS2) Homo sapiens (Human) lipid homeostasis [GO:0055088]; triglyceride catabolic process [GO:0019433] GO:0004623; GO:0004806; GO:0005737; GO:0005739; GO:0005811; GO:0005829; GO:0016020; GO:0016411; GO:0019433; GO:0047376; GO:0050253; GO:0051264; GO:0051265; GO:0055088 29698 XM_044323581.1 13 10 6 5 5 NA NA NA NA NA NA 29699 XM_044325494.1 46 3 39 3 84 NA NA NA NA NA NA 29700 XM_044316287.1 13 0 2 7 18 Q3UQ28 3.35e-21 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 29701 XR_006391468.1 0 0 91 31 55 NA NA NA NA NA NA 29702 XM_029350668.2 3306 2475 1524 2353 1014 Q08289 4.12e-125 Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2) (Lambert-Eaton myasthenic syndrome antigen B) (MYSB) Homo sapiens (Human) calcium ion import [GO:0070509]; chemical synaptic transmission [GO:0007268]; membrane depolarization during atrial cardiac muscle cell action potential [GO:0098912]; membrane depolarization during AV node cell action potential [GO:0086045]; neuromuscular junction development [GO:0007528]; positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel [GO:1904879]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of high voltage-gated calcium channel activity [GO:1901843]; protein localization to plasma membrane [GO:0072659]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of voltage-gated calcium channel activity [GO:1901385]; visual perception [GO:0007601] GO:0005245; GO:0005262; GO:0005886; GO:0005891; GO:0007268; GO:0007528; GO:0007601; GO:0051015; GO:0051928; GO:0070509; GO:0072659; GO:0086045; GO:0086091; GO:0098684; GO:0098793; GO:0098912; GO:0099626; GO:1901385; GO:1901843; GO:1904879; GO:1990454 29703 XR_006391610.1 6 0 0 0 1 NA NA NA NA NA NA 29704 XM_044308501.1 235 66 238 335 362 NA NA NA NA NA NA 29705 XM_044314517.1 225 145 87 200 55 NA NA NA NA NA NA 29706 XR_006391874.1 0 0 96 26 38 NA NA NA NA NA NA 29707 XM_044316700.1 177 239 35 94 369 NA NA NA NA NA NA 29708 XM_044318910.1 504 572 290 196 560 Q8BNA6 8.82e-50 Protocadherin Fat 3 (FAT tumor suppressor homolog 3) Mus musculus (Mouse) cell morphogenesis involved in differentiation [GO:0000904]; cell-cell adhesion [GO:0098609]; dendrite development [GO:0016358]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; interneuron migration [GO:1904936]; negative regulation of dendrite development [GO:2000171]; retina layer formation [GO:0010842] GO:0000904; GO:0005509; GO:0005886; GO:0007156; GO:0010842; GO:0016358; GO:0030425; GO:0098609; GO:1904936; GO:2000171 29709 XM_044318910.1 504 572 290 196 560 Q8BNA6 2.56e-37 Protocadherin Fat 3 (FAT tumor suppressor homolog 3) Mus musculus (Mouse) cell morphogenesis involved in differentiation [GO:0000904]; cell-cell adhesion [GO:0098609]; dendrite development [GO:0016358]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; interneuron migration [GO:1904936]; negative regulation of dendrite development [GO:2000171]; retina layer formation [GO:0010842] GO:0000904; GO:0005509; GO:0005886; GO:0007156; GO:0010842; GO:0016358; GO:0030425; GO:0098609; GO:1904936; GO:2000171 29710 XM_044318910.1 504 572 290 196 560 Q8BNA6 2.01e-32 Protocadherin Fat 3 (FAT tumor suppressor homolog 3) Mus musculus (Mouse) cell morphogenesis involved in differentiation [GO:0000904]; cell-cell adhesion [GO:0098609]; dendrite development [GO:0016358]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; interneuron migration [GO:1904936]; negative regulation of dendrite development [GO:2000171]; retina layer formation [GO:0010842] GO:0000904; GO:0005509; GO:0005886; GO:0007156; GO:0010842; GO:0016358; GO:0030425; GO:0098609; GO:1904936; GO:2000171 29711 XM_044318910.1 504 572 290 196 560 Q8BNA6 5.86e-32 Protocadherin Fat 3 (FAT tumor suppressor homolog 3) Mus musculus (Mouse) cell morphogenesis involved in differentiation [GO:0000904]; cell-cell adhesion [GO:0098609]; dendrite development [GO:0016358]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; interneuron migration [GO:1904936]; negative regulation of dendrite development [GO:2000171]; retina layer formation [GO:0010842] GO:0000904; GO:0005509; GO:0005886; GO:0007156; GO:0010842; GO:0016358; GO:0030425; GO:0098609; GO:1904936; GO:2000171 29712 XM_044318910.1 504 572 290 196 560 Q8BNA6 8.23e-31 Protocadherin Fat 3 (FAT tumor suppressor homolog 3) Mus musculus (Mouse) cell morphogenesis involved in differentiation [GO:0000904]; cell-cell adhesion [GO:0098609]; dendrite development [GO:0016358]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; interneuron migration [GO:1904936]; negative regulation of dendrite development [GO:2000171]; retina layer formation [GO:0010842] GO:0000904; GO:0005509; GO:0005886; GO:0007156; GO:0010842; GO:0016358; GO:0030425; GO:0098609; GO:1904936; GO:2000171 29713 XM_044318910.1 504 572 290 196 560 Q8BNA6 2.95e-29 Protocadherin Fat 3 (FAT tumor suppressor homolog 3) Mus musculus (Mouse) cell morphogenesis involved in differentiation [GO:0000904]; cell-cell adhesion [GO:0098609]; dendrite development [GO:0016358]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; interneuron migration [GO:1904936]; negative regulation of dendrite development [GO:2000171]; retina layer formation [GO:0010842] GO:0000904; GO:0005509; GO:0005886; GO:0007156; GO:0010842; GO:0016358; GO:0030425; GO:0098609; GO:1904936; GO:2000171 29714 XM_044318910.1 504 572 290 196 560 Q8BNA6 4.6e-25 Protocadherin Fat 3 (FAT tumor suppressor homolog 3) Mus musculus (Mouse) cell morphogenesis involved in differentiation [GO:0000904]; cell-cell adhesion [GO:0098609]; dendrite development [GO:0016358]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; interneuron migration [GO:1904936]; negative regulation of dendrite development [GO:2000171]; retina layer formation [GO:0010842] GO:0000904; GO:0005509; GO:0005886; GO:0007156; GO:0010842; GO:0016358; GO:0030425; GO:0098609; GO:1904936; GO:2000171 29715 XR_003825369.2 6 0 0 44 0 NA NA NA NA NA NA 29716 XR_006393792.1 29 34 56 30 35 NA NA NA NA NA NA 29717 XM_029333970.2 3 0 0 3 9 NA NA NA NA NA NA 29718 XM_044313183.1 13 7 28 8 27 Q09575 1.76e-29 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 29719 XM_044313183.1 13 7 28 8 27 Q09575 1.76e-29 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 29720 XM_044320167.1 35 20 0 15 0 NA NA NA NA NA NA 29721 XM_044323325.1 4 0 91 0 70 Q6P5F6 2.14e-43 Zinc transporter ZIP10 (Solute carrier family 39 member 10) (Zrt- and Irt-like protein 10) (ZIP-10) Mus musculus (Mouse) cellular zinc ion homeostasis [GO:0006882]; negative regulation of B cell apoptotic process [GO:0002903]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of B cell receptor signaling pathway [GO:0050861]; positive regulation of protein tyrosine phosphatase activity [GO:1903615]; zinc ion import across plasma membrane [GO:0071578] GO:0002903; GO:0005385; GO:0005886; GO:0006882; GO:0030890; GO:0050861; GO:0071578; GO:1903615 29722 XM_044322515.1 66 167 43 127 101 NA NA NA NA NA NA 29723 XM_029338745.2 4 0 0 16 1 NA NA NA NA NA NA 29724 XM_044317199.1 15 0 4 0 10 NA NA NA NA NA NA 29725 XR_006396029.1 8 2 2 0 10 NA NA NA NA NA NA 29726 XM_029345872.2 25 0 80 374 38 NA NA NA NA NA NA 29727 XM_044319792.1 865 470 449 999 668 Q9P2E3 0 NFX1-type zinc finger-containing protein 1 Homo sapiens (Human) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 29728 XM_044327671.1 0 0 90 0 0 Q498M4 0 WD repeat-containing protein 5 Rattus norvegicus (Rat) gluconeogenesis [GO:0006094]; histone H3 acetylation [GO:0043966]; histone H3-K14 acetylation [GO:0044154]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; negative regulation of histone H3-K4 methylation [GO:0051572]; neuron projection development [GO:0031175]; peptidyl-lysine methylation [GO:0018022]; positive regulation of gluconeogenesis [GO:0045722]; positive regulation of histone H3-K4 methylation [GO:0051571]; regulation of cell cycle [GO:0051726]; regulation of cell division [GO:0051302]; regulation of DNA-templated transcription [GO:0006355]; regulation of dosage compensation by inactivation of X chromosome [GO:1900095]; regulation of embryonic development [GO:0045995]; regulation of histone deacetylation [GO:0031063]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tubulin deacetylation [GO:0090043]; skeletal system development [GO:0001501]; transcription initiation-coupled chromatin remodeling [GO:0045815] GO:0000123; GO:0001501; GO:0005634; GO:0006094; GO:0006355; GO:0006357; GO:0018022; GO:0031063; GO:0031175; GO:0035064; GO:0035097; GO:0042393; GO:0042800; GO:0043966; GO:0043981; GO:0043982; GO:0043984; GO:0044154; GO:0044545; GO:0044665; GO:0044666; GO:0045722; GO:0045815; GO:0045995; GO:0048188; GO:0051302; GO:0051568; GO:0051571; GO:0051572; GO:0051726; GO:0071339; GO:0090043; GO:0140672; GO:1900095 29729 XR_006398046.1 182 171 98 140 161 NA NA NA NA NA NA 29730 XM_044321920.1 481 395 263 448 190 NA NA NA NA NA NA 29731 XM_029355947.2 258 404 144 314 126 Q26626 0 Kinesin-associated protein 3 (SpKAP115) Strongylocentrotus purpuratus (Purple sea urchin) cilium organization [GO:0044782]; microtubule-based movement [GO:0007018]; microtubule-based process [GO:0007017] GO:0005930; GO:0007017; GO:0007018; GO:0016939; GO:0019894; GO:0035869; GO:0044782 29732 XM_044311536.1 643 286 808 435 647 P35546 2.81e-73 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; anatomical structure morphogenesis [GO:0009653]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006919; GO:0007156; GO:0007158; GO:0007169; GO:0007399; GO:0009410; GO:0009653; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030182; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0098797; GO:2001241 29733 XM_029331205.2 0 0 58 0 0 P23416 3.6e-85 Glycine receptor subunit alpha-2 Homo sapiens (Human) cellular response to amino acid stimulus [GO:0071230]; cellular response to ethanol [GO:0071361]; cellular response to zinc ion [GO:0071294]; chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; neuropeptide signaling pathway [GO:0007218]; regulation of membrane potential [GO:0042391]; response to amino acid [GO:0043200]; signal transduction [GO:0007165]; synaptic transmission, glycinergic [GO:0060012] GO:0004888; GO:0005231; GO:0005886; GO:0007165; GO:0007218; GO:0007268; GO:0016594; GO:0016934; GO:0022852; GO:0030594; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0043200; GO:0045202; GO:0045211; GO:0046872; GO:0050877; GO:0060012; GO:0071230; GO:0071294; GO:0071361; GO:0098690; GO:1902476; GO:1904315 29734 XM_044310102.1 0 46 100 201 26 NA NA NA NA NA NA 29735 XR_006391927.1 88 59 33 56 131 NA NA NA NA NA NA 29736 XM_044316633.1 0 418 195 205 7 NA NA NA NA NA NA 29737 XM_044311251.1 5 22 9 22 80 NA NA NA NA NA NA 29738 XM_029327108.2 11 0 10 0 0 NA NA NA NA NA NA 29739 XM_029355589.2 59 12 30 17 136 Q8CJG0 0 Protein argonaute-2 (Argonaute2) (mAgo2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (Piwi/argonaute family protein meIF2C2) (Protein slicer) Mus musculus (Mouse) cell differentiation [GO:0030154]; miRNA metabolic process [GO:0010586]; miRNA processing [GO:0035196]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; miRNA-mediated gene silencing by mRNA destabilization [GO:0035279]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; negative regulation of translational initiation [GO:0045947]; positive regulation of angiogenesis [GO:0045766]; positive regulation of gene expression [GO:0010628]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of trophoblast cell migration [GO:1901165]; post-embryonic development [GO:0009791]; pre-miRNA processing [GO:0031054]; RISC complex assembly [GO:0070922]; RNA secondary structure unwinding [GO:0010501]; RNA-mediated gene silencing [GO:0031047]; siRNA processing [GO:0030422]; siRNA-mediated gene silencing by mRNA destabilization [GO:0090625] GO:0000340; GO:0000932; GO:0000993; GO:0001046; GO:0003723; GO:0003725; GO:0003727; GO:0003729; GO:0004521; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0005844; GO:0005845; GO:0008022; GO:0009791; GO:0010501; GO:0010586; GO:0010628; GO:0016442; GO:0030154; GO:0030422; GO:0030425; GO:0031047; GO:0031054; GO:0035196; GO:0035197; GO:0035198; GO:0035278; GO:0035279; GO:0036464; GO:0042985; GO:0045766; GO:0045944; GO:0045947; GO:0046872; GO:0060213; GO:0070062; GO:0070551; GO:0070578; GO:0070922; GO:0090624; GO:0090625; GO:0098808; GO:1900153; GO:1901165; GO:1990904 29740 XR_003826331.1 25 36 37 187 62 NA NA NA NA NA NA 29741 XR_006393081.1 41 2 25 5 151 NA NA NA NA NA NA 29742 XM_044319570.1 218 864 175 259 80 NA NA NA NA NA NA 29743 XM_029332097.2 1779 1469 1163 1224 1124 NA NA NA NA NA NA 29744 XM_044322400.1 20 0 0 77 94 Q96AY4 5.2e-94 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29745 XM_044322400.1 20 0 0 77 94 Q96AY4 2.15e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29746 XM_044322400.1 20 0 0 77 94 Q96AY4 2.4e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29747 XM_044322400.1 20 0 0 77 94 Q96AY4 1.95e-83 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29748 XM_044322400.1 20 0 0 77 94 Q96AY4 3.72e-83 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29749 XM_044322400.1 20 0 0 77 94 Q96AY4 8.61e-82 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29750 XM_044322400.1 20 0 0 77 94 Q96AY4 1.89e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29751 XM_044327363.1 0 15 0 0 0 Q09575 2.68e-48 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 29752 XM_044316931.1 31 8 35 17 29 NA NA NA NA NA NA 29753 XM_029355920.2 349 490 341 410 443 NA NA NA NA NA NA 29754 XM_044326380.1 26 10 27 8 127 NA NA NA NA NA NA 29755 XM_029350853.2 0 0 50 0 0 Q6VFT5 4.79e-54 Forkhead box protein L2 Oryctolagus cuniculus (Rabbit) apoptotic DNA fragmentation [GO:0006309]; cell differentiation [GO:0030154]; extraocular skeletal muscle development [GO:0002074]; ovarian follicle development [GO:0001541]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of DNA-templated transcription [GO:0045893] GO:0001541; GO:0002074; GO:0003677; GO:0003700; GO:0005634; GO:0006309; GO:0030154; GO:0043028; GO:0043065; GO:0043280; GO:0043565; GO:0045893 29756 XM_029327918.2 3967 3165 3104 3226 4203 G8HTB6 1.36e-35 ZP domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29757 XM_029356153.2 578 336 227 506 509 NA NA NA NA NA NA 29758 XM_029348162.2 3 10 0 12 1 Q2LC84 1.77e-50 Protein numb homolog Rattus norvegicus (Rat) adherens junction organization [GO:0034332]; axonogenesis [GO:0007409]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; forebrain development [GO:0030900]; lateral ventricle development [GO:0021670]; lung epithelial cell differentiation [GO:0060487]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein localization to plasma membrane [GO:1903077]; nervous system development [GO:0007399]; neuroblast division in subventricular zone [GO:0021849]; neuroblast proliferation [GO:0007405]; positive regulation of cell migration [GO:0030335]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of neurogenesis [GO:0050769]; positive regulation of polarized epithelial cell differentiation [GO:0030862]; regulation of neuron differentiation [GO:0045664]; regulation of postsynapse assembly [GO:0150052]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149] GO:0005543; GO:0005634; GO:0005737; GO:0005769; GO:0005886; GO:0005905; GO:0007399; GO:0007405; GO:0007409; GO:0008013; GO:0008283; GO:0010008; GO:0014069; GO:0016323; GO:0019897; GO:0021670; GO:0021849; GO:0030136; GO:0030154; GO:0030335; GO:0030862; GO:0030900; GO:0031410; GO:0034332; GO:0043197; GO:0045177; GO:0045294; GO:0045296; GO:0045664; GO:0045746; GO:0050769; GO:0050775; GO:0060487; GO:0098978; GO:0099149; GO:0150052; GO:1903077 29759 XR_006397140.1 185 350 116 276 282 NA NA NA NA NA NA 29760 XM_044308312.1 465 120 34 274 0 Q54PI5 8.51e-41 Probable gluconokinase (EC 2.7.1.12) (Gluconate kinase) Dictyostelium discoideum (Social amoeba) D-gluconate catabolic process [GO:0046177]; phosphorylation [GO:0016310] GO:0005524; GO:0016310; GO:0046177; GO:0046316 29761 XM_044329049.1 270 226 305 398 369 Q9UIC8 5.45e-114 Leucine carboxyl methyltransferase 1 (EC 2.1.1.233) (Protein-leucine O-methyltransferase) ([Phosphatase 2A protein]-leucine-carboxy methyltransferase 1) Homo sapiens (Human) C-terminal protein methylation [GO:0006481]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of protein-containing complex assembly [GO:0031333]; protein methylation [GO:0006479]; protein modification process [GO:0036211]; regulation of apoptotic process [GO:0042981]; regulation of glucose metabolic process [GO:0010906]; regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090266] GO:0000086; GO:0003880; GO:0005654; GO:0005829; GO:0006479; GO:0006481; GO:0008757; GO:0010906; GO:0018423; GO:0031333; GO:0036211; GO:0042981; GO:0090266 29762 XR_006395403.1 38 10 20 14 56 NA NA NA NA NA NA 29763 XM_029333277.2 28 12 12 16 20 O43345 1.47e-41 Zinc finger protein 208 (Zinc finger protein 91-like) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0008270 29764 XM_029333277.2 28 12 12 16 20 O43345 8.33e-38 Zinc finger protein 208 (Zinc finger protein 91-like) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0008270 29765 XM_029353175.2 5 2 1 0 17 NA NA NA NA NA NA 29766 XR_006395372.1 17 1 7 2 7 NA NA NA NA NA NA 29767 XM_029325586.2 982 745 784 2139 1666 NA NA NA NA NA NA 29768 XR_006392125.1 17 4 3 7 18 NA NA NA NA NA NA 29769 XM_029346050.2 73 8 27 25 96 P98161 1.3e-57 Polycystin-1 (PC1) (Autosomal dominant polycystic kidney disease 1 protein) Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; branching morphogenesis of an epithelial tube [GO:0048754]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; calcium-independent cell-matrix adhesion [GO:0007161]; cartilage condensation [GO:0001502]; cartilage development [GO:0051216]; cell-cell signaling by wnt [GO:0198738]; cell-matrix adhesion [GO:0007160]; cytoplasmic sequestering of transcription factor [GO:0042994]; detection of mechanical stimulus [GO:0050982]; digestive tract development [GO:0048565]; embryonic placenta development [GO:0001892]; establishment of epithelial cell polarity [GO:0090162]; genitalia development [GO:0048806]; heart development [GO:0007507]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; liver development [GO:0001889]; lung epithelium development [GO:0060428]; lymph vessel morphogenesis [GO:0036303]; mesonephric duct development [GO:0072177]; mesonephric tubule development [GO:0072164]; metanephric ascending thin limb development [GO:0072218]; metanephric collecting duct development [GO:0072205]; metanephric distal tubule morphogenesis [GO:0072287]; metanephric proximal tubule development [GO:0072237]; neural tube development [GO:0021915]; peptidyl-serine phosphorylation [GO:0018105]; placenta blood vessel development [GO:0060674]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of protein binding [GO:0032092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein export from nucleus [GO:0006611]; protein heterotetramerization [GO:0051290]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of cell adhesion [GO:0030155]; regulation of cell cycle [GO:0051726]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of mitotic spindle organization [GO:0060236]; regulation of proteasomal protein catabolic process [GO:0061136]; response to fluid shear stress [GO:0034405]; skin development [GO:0043588]; spinal cord development [GO:0021510] GO:0000139; GO:0001502; GO:0001701; GO:0001822; GO:0001889; GO:0001892; GO:0002133; GO:0005262; GO:0005634; GO:0005737; GO:0005783; GO:0005794; GO:0005886; GO:0005929; GO:0006611; GO:0006816; GO:0007156; GO:0007160; GO:0007161; GO:0007204; GO:0007259; GO:0007507; GO:0009653; GO:0009986; GO:0016020; GO:0016323; GO:0016328; GO:0018105; GO:0019901; GO:0019904; GO:0021510; GO:0021915; GO:0030155; GO:0030246; GO:0030660; GO:0031514; GO:0032092; GO:0034405; GO:0034703; GO:0034704; GO:0036303; GO:0042813; GO:0042994; GO:0043588; GO:0044325; GO:0045737; GO:0045944; GO:0048565; GO:0048754; GO:0048806; GO:0050982; GO:0051216; GO:0051290; GO:0051726; GO:0060170; GO:0060236; GO:0060428; GO:0060674; GO:0061136; GO:0070062; GO:0070588; GO:0072164; GO:0072177; GO:0072205; GO:0072218; GO:0072237; GO:0072287; GO:0090162; GO:0198738; GO:2000045 29770 XM_044328023.1 23 84 1 88 31 NA NA NA NA NA NA 29771 XR_006391550.1 29 0 14 0 38 NA NA NA NA NA NA 29772 XM_029340511.2 390 318 295 313 327 NA NA NA NA NA NA 29773 XM_044322996.1 1217 563 662 1004 1190 NA NA NA NA NA NA 29774 XM_044318522.1 0 8 0 1 56 A0JM23 7.87e-52 Nephrocystin-3 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cilium assembly [GO:0060271]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; Wnt signaling pathway [GO:0016055] GO:0005929; GO:0016055; GO:0060271; GO:0090090; GO:2000095 29775 XM_044318522.1 0 8 0 1 56 A0JM23 1.3e-51 Nephrocystin-3 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cilium assembly [GO:0060271]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; Wnt signaling pathway [GO:0016055] GO:0005929; GO:0016055; GO:0060271; GO:0090090; GO:2000095 29776 XM_044318522.1 0 8 0 1 56 A0JM23 6.25e-49 Nephrocystin-3 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cilium assembly [GO:0060271]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; Wnt signaling pathway [GO:0016055] GO:0005929; GO:0016055; GO:0060271; GO:0090090; GO:2000095 29777 XM_044318522.1 0 8 0 1 56 A0JM23 6.81e-49 Nephrocystin-3 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cilium assembly [GO:0060271]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; Wnt signaling pathway [GO:0016055] GO:0005929; GO:0016055; GO:0060271; GO:0090090; GO:2000095 29778 XM_044318522.1 0 8 0 1 56 A0JM23 6.99e-49 Nephrocystin-3 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cilium assembly [GO:0060271]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; Wnt signaling pathway [GO:0016055] GO:0005929; GO:0016055; GO:0060271; GO:0090090; GO:2000095 29779 XM_044309087.1 689 712 791 437 428 NA NA NA NA NA NA 29780 XM_029324486.2 0 0 13 0 10 NA NA NA NA NA NA 29781 XM_029329057.2 1004 826 602 923 942 Q6NUB2 7.23e-62 Protein CWC15 homolog A Xenopus laevis (African clawed frog) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0003723; GO:0005634; GO:0071007 29782 XM_044322360.1 0 4 0 14 5 Q2EG98 2.95e-55 Polycystic kidney disease protein 1-like 3 (PC1-like 3 protein) (Polycystin-1L3) Mus musculus (Mouse) cation transport [GO:0006812]; cellular response to acidic pH [GO:0071468]; detection of chemical stimulus involved in sensory perception of sour taste [GO:0001581]; detection of mechanical stimulus [GO:0050982]; sensory perception of sour taste [GO:0050915] GO:0001581; GO:0005262; GO:0005509; GO:0005886; GO:0006812; GO:0016020; GO:0030246; GO:0034703; GO:0043235; GO:0050915; GO:0050982; GO:0071468 29783 XM_044322360.1 0 4 0 14 5 Q2EG98 3.53e-42 Polycystic kidney disease protein 1-like 3 (PC1-like 3 protein) (Polycystin-1L3) Mus musculus (Mouse) cation transport [GO:0006812]; cellular response to acidic pH [GO:0071468]; detection of chemical stimulus involved in sensory perception of sour taste [GO:0001581]; detection of mechanical stimulus [GO:0050982]; sensory perception of sour taste [GO:0050915] GO:0001581; GO:0005262; GO:0005509; GO:0005886; GO:0006812; GO:0016020; GO:0030246; GO:0034703; GO:0043235; GO:0050915; GO:0050982; GO:0071468 29784 XM_044309312.1 130 74 68 78 139 NA NA NA NA NA NA 29785 XM_029352678.2 72 32 41 15 143 NA NA NA NA NA NA 29786 XM_029344537.2 0 6 1 10 5 NA NA NA NA NA NA 29787 XM_029340164.2 16 0 0 0 0 NA NA NA NA NA NA 29788 XR_006393613.1 0 0 0 9 0 NA NA NA NA NA NA 29789 XM_029345154.2 1232 60 1095 0 42 Q5ZL74 1.09e-90 Vesicle-associated membrane protein 7 (Synaptobrevin-like protein 1) Gallus gallus (Chicken) calcium-ion regulated exocytosis [GO:0017156]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endosome to lysosome transport [GO:0008333]; eosinophil degranulation [GO:0043308]; exocytosis [GO:0006887]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; protein transport [GO:0015031]; vesicle fusion [GO:0006906]; vesicle-mediated transport [GO:0016192] GO:0000149; GO:0005484; GO:0005765; GO:0005789; GO:0005794; GO:0006887; GO:0006888; GO:0006906; GO:0006911; GO:0008333; GO:0015031; GO:0016192; GO:0017156; GO:0030658; GO:0030670; GO:0031201; GO:0031902; GO:0043005; GO:0043308; GO:0043312; GO:0045202; GO:0045335 29790 XM_029337035.2 84 72 0 138 30 Q8HYZ1 8.31e-101 Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2) Mustela putorius furo (European domestic ferret) (Mustela furo) cardiac muscle cell action potential [GO:0086001]; cellular response to hypoxia [GO:0071456]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005250; GO:0005886; GO:0005901; GO:0008076; GO:0030315; GO:0032809; GO:0034765; GO:0042383; GO:0043197; GO:0043204; GO:0044853; GO:0045211; GO:0046872; GO:0051260; GO:0070161; GO:0071456; GO:0071805; GO:0086001 29791 XM_044310873.1 81 33 7 6 88 NA NA NA NA NA NA 29792 XM_029328841.2 836 811 553 298 726 Q3ZC91 3.07e-41 Acid sphingomyelinase-like phosphodiesterase 3a (ASM-like phosphodiesterase 3a) (EC 3.1.4.-) Bos taurus (Bovine) nucleoside triphosphate catabolic process [GO:0009143] GO:0005576; GO:0005615; GO:0008081; GO:0008270; GO:0009143 29793 XM_029352311.2 305 57 92 223 141 NA NA NA NA NA NA 29794 XR_006392615.1 687 262 215 470 346 NA NA NA NA NA NA 29795 XM_029337579.2 0 56 0 59 0 B6ZLK2 0 Chromodomain-helicase-DNA-binding protein 1 (CHD-1) (EC 3.6.4.12) (ATP-dependent helicase CHD1) Gallus gallus (Chicken) chromatin remodeling [GO:0006338]; nucleosome organization [GO:0034728]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000775; GO:0000785; GO:0003677; GO:0003682; GO:0004386; GO:0005524; GO:0005634; GO:0006338; GO:0006357; GO:0016887; GO:0034728; GO:0042393; GO:0140658 29796 XM_029337579.2 0 56 0 59 0 B6ZLK2 1.48e-27 Chromodomain-helicase-DNA-binding protein 1 (CHD-1) (EC 3.6.4.12) (ATP-dependent helicase CHD1) Gallus gallus (Chicken) chromatin remodeling [GO:0006338]; nucleosome organization [GO:0034728]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000775; GO:0000785; GO:0003677; GO:0003682; GO:0004386; GO:0005524; GO:0005634; GO:0006338; GO:0006357; GO:0016887; GO:0034728; GO:0042393; GO:0140658 29797 XM_029345008.2 0 26 0 0 19 NA NA NA NA NA NA 29798 XM_044306871.1 474 449 204 621 264 Q6PD21 1.51e-42 SH2 domain-containing adapter protein B Mus musculus (Mouse) angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; B cell proliferation [GO:0042100]; blood vessel development [GO:0001568]; blood vessel morphogenesis [GO:0048514]; hematopoietic stem cell proliferation [GO:0071425]; hemopoiesis [GO:0030097]; negative regulation of oocyte maturation [GO:1900194]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of T-helper cell differentiation [GO:0045624]; T cell receptor signaling pathway [GO:0050852] GO:0001525; GO:0001568; GO:0001784; GO:0005654; GO:0005829; GO:0005886; GO:0006469; GO:0006915; GO:0030097; GO:0030159; GO:0036464; GO:0042100; GO:0045624; GO:0045931; GO:0048514; GO:0050852; GO:0071425; GO:1900194 29799 XM_044314461.1 647 344 481 196 1122 NA NA NA NA NA NA 29800 XR_006392494.1 7 0 0 6 2 NA NA NA NA NA NA 29801 XM_029334973.2 41 28 57 261 15 NA NA NA NA NA NA 29802 XM_044321110.1 2465 3327 2672 3120 3031 Q5R6P6 1.92e-53 Glia maturation factor beta (GMF-beta) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) actin filament debranching [GO:0071846] GO:0003779; GO:0008083; GO:0071846; GO:0071933 29803 XM_029353928.2 585 509 367 584 497 NA NA NA NA NA NA 29804 XM_044317124.1 1392 350 240 319 264 NA NA NA NA NA NA 29805 XR_006395801.1 81 13 8 25 18 NA NA NA NA NA NA 29806 XM_044319731.1 686 706 273 698 909 Q5XIJ1 9.63e-90 Abasic site processing protein HMCES (Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein) (ES cell-specific 5hmC-binding protein) (Peptidase HMCES) (EC 3.4.-.-) (SRAP domain-containing protein 1) Rattus norvegicus (Rat) cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; positive regulation of isotype switching [GO:0045830]; protein-DNA covalent cross-linking [GO:0018142]; proteolysis [GO:0006508] GO:0003697; GO:0005657; GO:0006508; GO:0006974; GO:0008233; GO:0018142; GO:0045830; GO:0097681 29807 XM_044308790.1 102 112 61 112 264 NA NA NA NA NA NA 29808 XM_029327304.2 65 47 38 0 0 NA NA NA NA NA NA 29809 XM_044326001.1 8 0 3 0 0 Q5M954 9.3e-61 tRNA-splicing endonuclease subunit Sen2 (EC 4.6.1.16) (tRNA-intron endonuclease Sen2) Rattus norvegicus (Rat) mRNA processing [GO:0006397]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]; tRNA-type intron splice site recognition and cleavage [GO:0000379] GO:0000213; GO:0000214; GO:0000379; GO:0003676; GO:0005654; GO:0005730; GO:0005813; GO:0005829; GO:0006388; GO:0006397; GO:0016829 29810 XR_003825546.2 17 26 9 12 2 NA NA NA NA NA NA 29811 XM_029346156.2 0 20 0 0 0 Q9EPI9 0 Potassium voltage-gated channel subfamily H member 5 (Ether-a-go-go potassium channel 2) (rEAG2) (Voltage-gated potassium channel subunit Kv10.2) Rattus norvegicus (Rat) potassium ion transmembrane transport [GO:0071805]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391] GO:0005249; GO:0005516; GO:0005886; GO:0009986; GO:0010389; GO:0034765; GO:0042391; GO:0044325; GO:0044877; GO:0071805 29812 XM_044316152.1 15 9 0 0 1 NA NA NA NA NA NA 29813 XM_029345247.2 15 98 179 395 4663 O55057 8.09e-78 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (GMP-PDE delta) Mus musculus (Mouse) phototransduction [GO:0007602]; visual perception [GO:0007601] GO:0005095; GO:0005737; GO:0005829; GO:0005856; GO:0007601; GO:0007602; GO:0030659; GO:0031267; GO:0031410; GO:0042995; GO:0047555 29814 XM_029339560.2 0 9 41 68 65 Q17RD7 3.15e-75 Synaptotagmin-16 (Chr14Syt) (Synaptotagmin 14-like protein) (Synaptotagmin XIV-related protein) Homo sapiens (Human) NA GO:0005543; GO:0042802 29815 XM_044310952.1 0 3 1 17 69 P08419 8.47e-51 Chymotrypsin-like elastase family member 2A (EC 3.4.21.71) (Elastase-2) (Elastase-2A) Sus scrofa (Pig) insulin catabolic process [GO:1901143]; proteolysis [GO:0006508]; regulation of insulin secretion [GO:0050796]; regulation of platelet aggregation [GO:0090330]; response to insulin [GO:0032868] GO:0004175; GO:0004252; GO:0005576; GO:0005615; GO:0006508; GO:0032868; GO:0050796; GO:0090330; GO:1901143 29816 XM_044323726.1 2 1 0 3 23 NA NA NA NA NA NA 29817 XM_029339421.2 202 0 62 0 127 Q7T163 0 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 29818 XM_029339421.2 202 0 62 0 127 Q7T163 3.34e-42 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 29819 XM_029339421.2 202 0 62 0 127 Q7T163 3.24e-33 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 29820 XM_029339421.2 202 0 62 0 127 Q7T163 1.97e-29 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 29821 XM_029339421.2 202 0 62 0 127 Q7T163 5.08e-27 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 29822 XM_029339421.2 202 0 62 0 127 Q7T163 1.11e-22 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 29823 XM_044307238.1 543 365 133 326 160 NA NA NA NA NA NA 29824 XR_006397510.1 149 15 151 169 232 NA NA NA NA NA NA 29825 XM_029334213.2 1 0 0 0 6 NA NA NA NA NA NA 29826 XM_044327667.1 27 4 7 4 14 NA NA NA NA NA NA 29827 XR_006396266.1 34 12 9 20 12 NA NA NA NA NA NA 29828 XR_006394345.1 8 3 0 0 17 NA NA NA NA NA NA 29829 XM_044306797.1 85 5 30 49 53 Q2TBG7 1.66e-35 Iron-sulfur cluster assembly 2 homolog, mitochondrial (HESB-like domain-containing protein 1) Bos taurus (Bovine) iron-sulfur cluster assembly [GO:0016226]; protein maturation by [4Fe-4S] cluster transfer [GO:0106035] GO:0005506; GO:0005739; GO:0016226; GO:0042802; GO:0051537; GO:0051539; GO:0106035 29830 XM_044324902.1 0 0 66 11 0 Q9UQ26 1.81e-63 Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2) (Rab-3-interacting protein 3) Homo sapiens (Human) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-ion regulated exocytosis [GO:0017156]; cell differentiation [GO:0030154]; insulin secretion [GO:0030073]; intracellular protein transport [GO:0006886]; positive regulation of dendrite extension [GO:1903861]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of synaptic transmission [GO:0050806]; regulation of exocytosis [GO:0017157]; regulation of membrane potential [GO:0042391]; regulation of synaptic plasticity [GO:0048167]; spontaneous neurotransmitter secretion [GO:0061669] GO:0006886; GO:0007188; GO:0017156; GO:0017157; GO:0030073; GO:0030154; GO:0031267; GO:0042391; GO:0042734; GO:0042995; GO:0044325; GO:0046872; GO:0048167; GO:0048786; GO:0048788; GO:0048791; GO:0050806; GO:0061669; GO:0070062; GO:0097151; GO:1903861; GO:2000463 29831 XM_044324902.1 0 0 66 11 0 Q9UQ26 1.44e-30 Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2) (Rab-3-interacting protein 3) Homo sapiens (Human) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-ion regulated exocytosis [GO:0017156]; cell differentiation [GO:0030154]; insulin secretion [GO:0030073]; intracellular protein transport [GO:0006886]; positive regulation of dendrite extension [GO:1903861]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of synaptic transmission [GO:0050806]; regulation of exocytosis [GO:0017157]; regulation of membrane potential [GO:0042391]; regulation of synaptic plasticity [GO:0048167]; spontaneous neurotransmitter secretion [GO:0061669] GO:0006886; GO:0007188; GO:0017156; GO:0017157; GO:0030073; GO:0030154; GO:0031267; GO:0042391; GO:0042734; GO:0042995; GO:0044325; GO:0046872; GO:0048167; GO:0048786; GO:0048788; GO:0048791; GO:0050806; GO:0061669; GO:0070062; GO:0097151; GO:1903861; GO:2000463 29832 XR_003825269.2 0 14 0 0 0 NA NA NA NA NA NA 29833 XM_044320278.1 20 232 12 48 70 P10079 2.19e-153 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 29834 XM_044320278.1 20 232 12 48 70 P10079 1.8e-151 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 29835 XM_044320278.1 20 232 12 48 70 P10079 5.93e-150 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 29836 XM_029323800.2 872 761 82 1316 505 Q7T2C4 4.14e-129 NA NA NA NA 29837 XM_029326704.2 75 21 54 68 103 Q6GNV7 8.67e-84 Solute carrier family 49 member 4 homolog (Disrupted in renal carcinoma protein 2 homolog) Xenopus laevis (African clawed frog) NA GO:0005765; GO:0022857 29838 XR_006392661.1 500 685 76 91 449 NA NA NA NA NA NA 29839 XM_029339470.2 539 630 210 194 240 O60381 3.04e-37 HMG box-containing protein 1 (HMG box transcription factor 1) (High mobility group box transcription factor 1) Homo sapiens (Human) regulation of cell cycle [GO:0051726]; regulation of transcription by RNA polymerase II [GO:0006357]; Wnt signaling pathway [GO:0016055] GO:0000785; GO:0000978; GO:0000981; GO:0003723; GO:0005634; GO:0005654; GO:0006357; GO:0016055; GO:0016607; GO:0051726 29840 XM_044314079.1 601 61 71 26 97 NA NA NA NA NA NA 29841 XR_006396270.1 22 2 54 19 146 NA NA NA NA NA NA 29842 XM_029333841.2 0 15 0 85 0 NA NA NA NA NA NA 29843 XM_029330177.2 189 56 188 91 413 Q58CR4 4.54e-52 Dolichol kinase (EC 2.7.1.108) (Transmembrane protein 15) Bos taurus (Bovine) dolichyl monophosphate biosynthetic process [GO:0043048]; phosphorylation [GO:0016310] GO:0004168; GO:0005789; GO:0016310; GO:0043048 29844 XM_029338603.2 884 564 383 702 964 Q925C0 2.19e-48 Synaptotagmin-9 (Synaptotagmin 5) (Synaptotagmin IX) (SytIX) (Synaptotagmin V) Rattus norvegicus (Rat) calcium-dependent activation of synaptic vesicle fusion [GO:0099502]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; detection of calcium ion [GO:0005513]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of insulin secretion [GO:0050796]; vesicle-mediated transport [GO:0016192] GO:0000149; GO:0001786; GO:0005509; GO:0005513; GO:0005544; GO:0005546; GO:0005886; GO:0014059; GO:0016192; GO:0017156; GO:0017158; GO:0019905; GO:0030141; GO:0030276; GO:0030667; GO:0030672; GO:0031045; GO:0042802; GO:0045956; GO:0050796; GO:0070382; GO:0071277; GO:0098686; GO:0099502 29845 XR_003827270.2 85 60 58 78 155 NA NA NA NA NA NA 29846 XM_044321723.1 4 272 0 97 0 NA NA NA NA NA NA 29847 XM_044319852.1 6 16 0 0 33 NA NA NA NA NA NA 29848 XM_029343061.2 6 16 21 0 0 P54833 1.06e-24 Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor) Canis lupus familiaris (Dog) (Canis familiaris) activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; desensitization of G protein-coupled receptor signaling pathway by arrestin [GO:0002032]; negative regulation of smooth muscle contraction [GO:0045986]; norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0002025]; positive regulation of autophagosome maturation [GO:1901098]; positive regulation of lipophagy [GO:1904504]; positive regulation of MAPK cascade [GO:0043410]; receptor-mediated endocytosis [GO:0006898] GO:0002025; GO:0002032; GO:0004930; GO:0004941; GO:0005769; GO:0005794; GO:0005886; GO:0006898; GO:0007190; GO:0042803; GO:0043235; GO:0043410; GO:0045986; GO:0051380; GO:0071880; GO:1901098; GO:1904504 29849 XM_029327551.2 32 56 7 23 31 NA NA NA NA NA NA 29850 XM_029351491.2 24 0 0 39 38 NA NA NA NA NA NA 29851 XM_044328335.1 383 327 265 501 923 NA NA NA NA NA NA 29852 XR_003824545.2 0 0 15 0 14 NA NA NA NA NA NA 29853 XM_044308260.1 99 14 0 0 0 NA NA NA NA NA NA 29854 XM_044321529.1 14 10 15 46 58 NA NA NA NA NA NA 29855 XM_044308062.1 9 9 17 10 8 NA NA NA NA NA NA 29856 XM_044324583.1 0 1 0 0 12 NA NA NA NA NA NA 29857 XM_029351544.2 1032 817 182 1318 699 Q75N73 8.06e-62 Metal cation symporter ZIP14 (Factor for adipocyte differentiation 123) (FAD-123) (Solute carrier family 39 member 14) (Zrt- and Irt-like protein 14) (ZIP-14) Mus musculus (Mouse) cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; cellular zinc ion homeostasis [GO:0006882]; chondrocyte differentiation [GO:0002062]; gluconeogenesis [GO:0006094]; import across plasma membrane [GO:0098739]; inorganic cation transmembrane transport [GO:0098662]; insulin receptor signaling pathway [GO:0008286]; iron import into cell [GO:0033212]; iron ion transmembrane transport [GO:0034755]; iron ion transport [GO:0006826]; manganese ion homeostasis [GO:0055071]; manganese ion transmembrane transport [GO:0071421]; negative regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051344]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; regulation of hormone levels [GO:0010817]; zinc ion import across plasma membrane [GO:0071578]; zinc ion transmembrane transport [GO:0071577]; zinc ion transport [GO:0006829] GO:0002062; GO:0005381; GO:0005384; GO:0005385; GO:0005765; GO:0005886; GO:0006094; GO:0006826; GO:0006829; GO:0006882; GO:0008286; GO:0010817; GO:0015086; GO:0015093; GO:0015296; GO:0016020; GO:0016323; GO:0016324; GO:0031901; GO:0031902; GO:0032869; GO:0033212; GO:0034755; GO:0045745; GO:0051344; GO:0055071; GO:0071333; GO:0071421; GO:0071577; GO:0071578; GO:0098662; GO:0098739 29858 XM_044307587.1 736 569 361 779 661 A6NNL5 3.51e-50 Uncharacterized protein C15orf61 Homo sapiens (Human) NA GO:0005576 29859 XM_029340377.2 90 105 70 78 148 NA NA NA NA NA NA 29860 XR_006391303.1 55 50 55 73 86 Q6RI86 8.57e-73 Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Wasabi receptor) Rattus norvegicus (Rat) calcium ion transmembrane import into cytosol [GO:0097553]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cell surface receptor signaling pathway [GO:0007166]; cellular calcium ion homeostasis [GO:0006874]; cellular response to caffeine [GO:0071313]; cellular response to carbon dioxide [GO:0071244]; cellular response to cold [GO:0070417]; cellular response to heat [GO:0034605]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to organic substance [GO:0071310]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; ion transmembrane transport [GO:0034220]; positive regulation of anion transport [GO:1903793]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of sensory perception of pain [GO:1904058]; protein homotetramerization [GO:0051289]; regulation of blood circulation [GO:1903522]; regulation of neuronal action potential [GO:0098908]; response to cold [GO:0009409]; response to hydrogen peroxide [GO:0042542]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; sensory perception of pain [GO:0019233]; thermoception [GO:0050955]; transmembrane transport [GO:0055085]; urinary bladder smooth muscle contraction [GO:0014832] GO:0005216; GO:0005245; GO:0005262; GO:0005886; GO:0006816; GO:0006874; GO:0007166; GO:0009409; GO:0009410; GO:0010033; GO:0014070; GO:0014832; GO:0015267; GO:0015278; GO:0016324; GO:0019233; GO:0030424; GO:0032421; GO:0034220; GO:0034605; GO:0035774; GO:0042542; GO:0042802; GO:0048265; GO:0050955; GO:0050966; GO:0050968; GO:0050974; GO:0051289; GO:0055085; GO:0070301; GO:0070417; GO:0070588; GO:0071244; GO:0071310; GO:0071313; GO:0097553; GO:0097604; GO:0098908; GO:1903522; GO:1903793; GO:1904058; GO:1990760 29861 XR_006391303.1 55 50 55 73 86 Q6RI86 8.57e-73 Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Wasabi receptor) Rattus norvegicus (Rat) calcium ion transmembrane import into cytosol [GO:0097553]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cell surface receptor signaling pathway [GO:0007166]; cellular calcium ion homeostasis [GO:0006874]; cellular response to caffeine [GO:0071313]; cellular response to carbon dioxide [GO:0071244]; cellular response to cold [GO:0070417]; cellular response to heat [GO:0034605]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to organic substance [GO:0071310]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; ion transmembrane transport [GO:0034220]; positive regulation of anion transport [GO:1903793]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of sensory perception of pain [GO:1904058]; protein homotetramerization [GO:0051289]; regulation of blood circulation [GO:1903522]; regulation of neuronal action potential [GO:0098908]; response to cold [GO:0009409]; response to hydrogen peroxide [GO:0042542]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; sensory perception of pain [GO:0019233]; thermoception [GO:0050955]; transmembrane transport [GO:0055085]; urinary bladder smooth muscle contraction [GO:0014832] GO:0005216; GO:0005245; GO:0005262; GO:0005886; GO:0006816; GO:0006874; GO:0007166; GO:0009409; GO:0009410; GO:0010033; GO:0014070; GO:0014832; GO:0015267; GO:0015278; GO:0016324; GO:0019233; GO:0030424; GO:0032421; GO:0034220; GO:0034605; GO:0035774; GO:0042542; GO:0042802; GO:0048265; GO:0050955; GO:0050966; GO:0050968; GO:0050974; GO:0051289; GO:0055085; GO:0070301; GO:0070417; GO:0070588; GO:0071244; GO:0071310; GO:0071313; GO:0097553; GO:0097604; GO:0098908; GO:1903522; GO:1903793; GO:1904058; GO:1990760 29862 XM_029338816.2 15 0 0 0 0 NA NA NA NA NA NA 29863 XM_044315297.1 582 377 199 350 51 NA NA NA NA NA NA 29864 XM_029346853.2 1568 1564 1777 3709 4841 Q9Z2J0 6.81e-165 Solute carrier family 23 member 1 (Na(+)/L-ascorbic acid transporter 1) (Sodium-dependent vitamin C transporter 1) (Yolk sac permease-like molecule 3) Mus musculus (Mouse) brain development [GO:0007420]; dehydroascorbic acid transport [GO:0070837]; L-ascorbic acid transmembrane transport [GO:0015882]; lung development [GO:0030324]; response to toxic substance [GO:0009636]; sodium ion transport [GO:0006814] GO:0005737; GO:0005886; GO:0005903; GO:0006814; GO:0007420; GO:0008520; GO:0009636; GO:0009925; GO:0015081; GO:0015229; GO:0015882; GO:0016324; GO:0030324; GO:0033300; GO:0043229; GO:0070837 29865 XM_044313608.1 0 0 0 11 0 NA NA NA NA NA NA 29866 XM_029330979.2 22 9 33 4 44 Q09081 2.93e-67 Potassium voltage-gated channel subfamily A member 2 (KC22) (Voltage-gated potassium channel subunit Kv1.2) Oryctolagus cuniculus (Rabbit) neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233] GO:0005249; GO:0005251; GO:0005789; GO:0005886; GO:0008076; GO:0014059; GO:0019228; GO:0019233; GO:0021633; GO:0030027; GO:0030424; GO:0030425; GO:0031258; GO:0032809; GO:0033010; GO:0034765; GO:0042734; GO:0043194; GO:0043204; GO:0043679; GO:0044224; GO:0045188; GO:0051260; GO:0071805 29867 XR_006397393.1 25 53 53 186 116 NA NA NA NA NA NA 29868 XR_006394750.1 42 34 9 7 34 NA NA NA NA NA NA 29869 XM_044325351.1 35 11 58 74 151 P48733 2.32e-32 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Bos taurus (Bovine) antibacterial innate immune response [GO:0140367]; defense response to Gram-negative bacterium [GO:0050829] GO:0000922; GO:0005201; GO:0005509; GO:0005576; GO:0005929; GO:0016020; GO:0016323; GO:0016324; GO:0031012; GO:0050829; GO:0060170; GO:0140367 29870 XM_029335949.2 540 446 340 638 930 NA NA NA NA NA NA 29871 XM_029350173.2 13 30 4 8 15 Q9H8H3 5.41e-50 Putative methyltransferase-like protein 7A (EC 2.1.1.-) (Protein AAM-B) Homo sapiens (Human) methylation [GO:0032259] GO:0005576; GO:0005783; GO:0005811; GO:0008168; GO:0016020; GO:0032259; GO:1904724 29872 XR_003824642.2 176 82 40 127 201 NA NA NA NA NA NA 29873 XM_029356245.2 1620 1068 1068 1662 1058 P70182 4.14e-180 Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (PIP5K1-alpha) (PtdIns(4)P-5-kinase 1 alpha) (EC 2.7.1.68) (68 kDa type I phosphatidylinositol 4-phosphate 5-kinase alpha) (Phosphatidylinositol 4-phosphate 5-kinase type I alpha) (PIP5KIalpha) (Phosphatidylinositol 4-phosphate 5-kinase type I beta) (PI4P5KIbeta) Mus musculus (Mouse) actin cytoskeleton reorganization [GO:0031532]; activation of GTPase activity [GO:0090630]; cell chemotaxis [GO:0060326]; fibroblast migration [GO:0010761]; focal adhesion assembly [GO:0048041]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol metabolic process [GO:0046488]; phosphatidylinositol phosphate biosynthetic process [GO:0046854]; phospholipid biosynthetic process [GO:0008654]; phosphorylation [GO:0016310]; protein localization to plasma membrane [GO:0072659]; ruffle assembly [GO:0097178] GO:0005524; GO:0005634; GO:0005654; GO:0005829; GO:0005847; GO:0005886; GO:0006661; GO:0008654; GO:0010761; GO:0016308; GO:0016310; GO:0016607; GO:0019900; GO:0030027; GO:0031532; GO:0032587; GO:0046488; GO:0046854; GO:0048041; GO:0060326; GO:0072659; GO:0090630; GO:0097178 29874 XM_029349341.2 2261 2347 1680 1954 1809 Q2HJA9 2.67e-50 Phosducin-like protein (PHLP) Bos taurus (Bovine) cell projection organization [GO:0030030]; heterotrimeric G-protein complex assembly [GO:1902605]; positive regulation of smoothened signaling pathway [GO:0045880]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; response to stimulus [GO:0050896]; visual perception [GO:0007601] GO:0005737; GO:0005929; GO:0007601; GO:0008277; GO:0030030; GO:0045880; GO:0050896; GO:1902605 29875 XR_006393905.1 41 2 25 5 151 NA NA NA NA NA NA 29876 XR_006394524.1 2 0 9 0 30 NA NA NA NA NA NA 29877 XM_029339941.2 11 0 0 0 8 Q09081 8.4e-90 Potassium voltage-gated channel subfamily A member 2 (KC22) (Voltage-gated potassium channel subunit Kv1.2) Oryctolagus cuniculus (Rabbit) neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233] GO:0005249; GO:0005251; GO:0005789; GO:0005886; GO:0008076; GO:0014059; GO:0019228; GO:0019233; GO:0021633; GO:0030027; GO:0030424; GO:0030425; GO:0031258; GO:0032809; GO:0033010; GO:0034765; GO:0042734; GO:0043194; GO:0043204; GO:0043679; GO:0044224; GO:0045188; GO:0051260; GO:0071805 29878 XM_044313050.1 51 13 22 75 7 NA NA NA NA NA NA 29879 XM_044328104.1 0 43 0 0 168 NA NA NA NA NA NA 29880 XM_044309517.1 13 0 2 1 0 P79218 1.6e-42 Substance-K receptor (SKR) (NK-2 receptor) (NK-2R) (Neurokinin A receptor) (Tachykinin receptor 2) Oryctolagus cuniculus (Rabbit) positive regulation of flagellated sperm motility [GO:1902093]; regulation of uterine smooth muscle contraction [GO:0070472] GO:0004995; GO:0005886; GO:0061827; GO:0070472; GO:0097225; GO:1902093 29881 XR_006394090.1 0 46 0 49 27 NA NA NA NA NA NA 29882 XM_044312440.1 499 235 457 585 534 Q8NBF2 0 NHL repeat-containing protein 2 Homo sapiens (Human) NA GO:0005576; GO:0005829; GO:0031093 29883 XM_044325019.1 0 63 0 289 91 NA NA NA NA NA NA 29884 XM_029339050.2 261 128 227 102 122 O95822 2.55e-111 Malonyl-CoA decarboxylase, mitochondrial (MCD) (EC 4.1.1.9) Homo sapiens (Human) acetyl-CoA biosynthetic process [GO:0006085]; acyl-CoA metabolic process [GO:0006637]; fatty acid biosynthetic process [GO:0006633]; fatty acid oxidation [GO:0019395]; malonyl-CoA catabolic process [GO:2001294]; positive regulation of fatty acid oxidation [GO:0046321]; regulation of fatty acid beta-oxidation [GO:0031998]; regulation of glucose metabolic process [GO:0010906]; response to ischemia [GO:0002931] GO:0002931; GO:0005737; GO:0005739; GO:0005759; GO:0005777; GO:0005782; GO:0005829; GO:0006085; GO:0006633; GO:0006637; GO:0010906; GO:0019395; GO:0031998; GO:0042802; GO:0046321; GO:0050080; GO:2001294 29885 XR_003828635.1 1 0 0 3 6 NA NA NA NA NA NA 29886 XM_029326267.2 7 3 0 0 4 NA NA NA NA NA NA 29887 XR_003822922.2 10 9 0 10 5 NA NA NA NA NA NA 29888 XM_029353995.2 1861 1713 990 1449 709 Q5RFI2 2.06e-92 Ras-related protein Rab-28 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003924; GO:0005525; GO:0005737; GO:0005886; GO:0019003; GO:0035253; GO:0036064 29889 XR_006395851.1 18 0 0 0 15 NA NA NA NA NA NA 29890 XM_029327909.2 373 259 190 394 377 NA NA NA NA NA NA 29891 XM_044327751.1 41 1 7 4 53 Q05609 1.02e-24 Serine/threonine-protein kinase CTR1 (EC 2.7.11.1) (Protein CONSTITUTIVE TRIPLE RESPONSE1) Arabidopsis thaliana (Mouse-ear cress) ethylene-activated signaling pathway [GO:0009873]; gibberellin biosynthetic process [GO:0009686]; negative regulation of ethylene-activated signaling pathway [GO:0010105]; protein autophosphorylation [GO:0046777]; regulation of post-embryonic root development [GO:2000069]; regulation of stem cell division [GO:2000035]; regulation of timing of transition from vegetative to reproductive phase [GO:0048510]; response to ethylene [GO:0009723]; response to fructose [GO:0009750]; response to hypoxia [GO:0001666]; response to sucrose [GO:0009744]; sugar mediated signaling pathway [GO:0010182] GO:0001666; GO:0004674; GO:0004712; GO:0005524; GO:0005789; GO:0009686; GO:0009723; GO:0009744; GO:0009750; GO:0009873; GO:0010105; GO:0010182; GO:0046777; GO:0048510; GO:0106310; GO:2000035; GO:2000069 29892 XM_044318676.1 850 105 823 323 2800 NA NA NA NA NA NA 29893 XR_006392354.1 9 0 11 6 38 NA NA NA NA NA NA 29894 XM_044317404.1 0 40 19 12 4 NA NA NA NA NA NA 29895 XM_044310966.1 8 11 11 23 32 NA NA NA NA NA NA 29896 XR_003828566.2 2270 1665 1038 3162 4450 NA NA NA NA NA NA 29897 XM_029327313.2 26 7 56 4 48 NA NA NA NA NA NA 29898 XM_044327041.1 915 598 960 818 952 NA NA NA NA NA NA 29899 XM_029354902.2 768 288 349 568 852 E7F211 1.52e-48 Tetratricopeptide repeat protein 17 (TPR repeat protein 17) Danio rerio (Zebrafish) (Brachydanio rerio) actin filament polymerization [GO:0030041]; cilium organization [GO:0044782]; determination of heart left/right asymmetry [GO:0061371] GO:0005737; GO:0005886; GO:0015629; GO:0030041; GO:0044782; GO:0061371 29900 XM_029354902.2 768 288 349 568 852 E7F211 6.26e-47 Tetratricopeptide repeat protein 17 (TPR repeat protein 17) Danio rerio (Zebrafish) (Brachydanio rerio) actin filament polymerization [GO:0030041]; cilium organization [GO:0044782]; determination of heart left/right asymmetry [GO:0061371] GO:0005737; GO:0005886; GO:0015629; GO:0030041; GO:0044782; GO:0061371 29901 XM_029354902.2 768 288 349 568 852 E7F211 6.76e-28 Tetratricopeptide repeat protein 17 (TPR repeat protein 17) Danio rerio (Zebrafish) (Brachydanio rerio) actin filament polymerization [GO:0030041]; cilium organization [GO:0044782]; determination of heart left/right asymmetry [GO:0061371] GO:0005737; GO:0005886; GO:0015629; GO:0030041; GO:0044782; GO:0061371 29902 XM_029354902.2 768 288 349 568 852 E7F211 5.79e-27 Tetratricopeptide repeat protein 17 (TPR repeat protein 17) Danio rerio (Zebrafish) (Brachydanio rerio) actin filament polymerization [GO:0030041]; cilium organization [GO:0044782]; determination of heart left/right asymmetry [GO:0061371] GO:0005737; GO:0005886; GO:0015629; GO:0030041; GO:0044782; GO:0061371 29903 XM_029350336.2 12 4 1 2 6 Q80XJ3 9.22e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 29904 XM_044322431.1 55 49 11 121 11 NA NA NA NA NA NA 29905 XM_029341982.2 462 269 249 387 754 Q92072 0 DNA (cytosine-5)-methyltransferase 1 (Dnmt1) (EC 2.1.1.37) (DNA methyltransferase GgaI) (DNA MTase GgaI) (M.GgaI) (MCMT) Gallus gallus (Chicken) positive regulation of DNA methylation-dependent heterochromatin formation [GO:0090309] GO:0003677; GO:0003886; GO:0005634; GO:0008270; GO:0090309; GO:1990841 29906 XM_044317921.1 43 41 51 37 87 NA NA NA NA NA NA 29907 XM_044319465.1 120 77 76 14 36 NA NA NA NA NA NA 29908 XM_029330993.2 746 552 395 938 919 Q3YBR2 2.98e-61 Transforming growth factor beta regulator 1 (Nuclear interactor of ARF and Mdm2) Homo sapiens (Human) cell cycle [GO:0007049]; DNA replication [GO:0006260]; negative regulation of cell population proliferation [GO:0008285]; protein localization to nucleoplasm [GO:1990173]; protein stabilization [GO:0050821]; regulation of cell cycle [GO:0051726] GO:0005634; GO:0005654; GO:0006260; GO:0007049; GO:0008285; GO:0050821; GO:0051726; GO:1990173 29909 XM_044311648.1 0 1 10 24 1 NA NA NA NA NA NA 29910 XR_006391413.1 5 81 2 5 7 NA NA NA NA NA NA 29911 XM_044307911.1 1 7 0 4 1 NA NA NA NA NA NA 29912 XR_006393698.1 41 23 21 26 68 NA NA NA NA NA NA 29913 XR_006397588.1 1925 1273 780 1772 1612 Q02446 1.13e-63 Transcription factor Sp4 (SPR-1) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000785; GO:0000978; GO:0000981; GO:0005654; GO:0005829; GO:0006357; GO:0042802; GO:0043565; GO:0046872 29914 XR_003828535.2 55 32 25 60 132 NA NA NA NA NA NA 29915 XM_029331330.2 0 0 1 14 23 Q9YH18 1.31e-62 KH domain-containing RNA-binding protein QKI (Protein quaking) Gallus gallus (Chicken) long-chain fatty acid biosynthetic process [GO:0042759]; mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; myelination [GO:0042552]; positive regulation of gene expression [GO:0010628]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of translation [GO:0006417]; RNA splicing [GO:0008380]; spermatid development [GO:0007286]; vascular associated smooth muscle cell differentiation [GO:0035886]; vasculogenesis [GO:0001570] GO:0001570; GO:0003729; GO:0005634; GO:0005737; GO:0006397; GO:0006417; GO:0007286; GO:0008380; GO:0010628; GO:0017124; GO:0035886; GO:0042552; GO:0042759; GO:0045202; GO:0048024; GO:0051028 29916 XM_044311671.1 55 5 36 40 226 NA NA NA NA NA NA 29917 XM_029350264.2 57 0 99 11 224 Q91XQ0 0 Dynein axonemal heavy chain 8 (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8) Mus musculus (Mouse) cilium movement [GO:0003341]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003777; GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0036126; GO:0036157; GO:0036158; GO:0045505; GO:0051959 29918 XR_006392796.1 243 0 61 23 199 NA NA NA NA NA NA 29919 XM_044310874.1 1 13 21 0 5 NA NA NA NA NA NA 29920 XM_044327707.1 3189 2021 1660 3550 2766 Q3UU96 0 Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) Mus musculus (Mouse) actin cytoskeleton reorganization [GO:0031532]; actomyosin structure organization [GO:0031032]; cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; microtubule cytoskeleton organization [GO:0000226]; nuclear migration [GO:0007097]; peptidyl-threonine phosphorylation [GO:0018107]; protein phosphorylation [GO:0006468]; regulation of small GTPase mediated signal transduction [GO:0051056] GO:0000226; GO:0000287; GO:0004674; GO:0005524; GO:0005737; GO:0005856; GO:0005911; GO:0006468; GO:0007010; GO:0007097; GO:0016477; GO:0018107; GO:0030027; GO:0031032; GO:0031252; GO:0031532; GO:0042641; GO:0042802; GO:0051056; GO:0106310 29921 XM_029335447.2 1090 796 603 904 822 Q9H3P7 3.54e-42 Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi complex-associated protein 1) (GOCAP1) (Golgi phosphoprotein 1) (GOLPH1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7) [Cleaved into: Golgi resident protein GCP60, N-terminally processed] Homo sapiens (Human) steroid biosynthetic process [GO:0006694] GO:0000062; GO:0000139; GO:0005739; GO:0005794; GO:0006694; GO:0016020; GO:0034237 29922 XM_044313315.1 0 0 193 0 212 NA NA NA NA NA NA 29923 XM_029350813.2 10 25 10 11 1 P35346 2.88e-30 Somatostatin receptor type 5 (SS-5-R) (SS5-R) (SS5R) (SST5) Homo sapiens (Human) cellular response to glucocorticoid stimulus [GO:0071385]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; glucose homeostasis [GO:0042593]; negative regulation of cell population proliferation [GO:0008285]; neuropeptide signaling pathway [GO:0007218]; positive regulation of cytokinesis [GO:0032467]; regulation of insulin secretion [GO:0050796] GO:0004930; GO:0004994; GO:0005886; GO:0007186; GO:0007187; GO:0007218; GO:0008285; GO:0032467; GO:0042277; GO:0042593; GO:0042923; GO:0043005; GO:0050796; GO:0071385 29924 XM_029349404.2 3 0 0 9 48 NA NA NA NA NA NA 29925 XM_029350477.2 5 0 0 0 8 Q54468 4.81e-153 Chitobiase (EC 3.2.1.52) (Beta-N-acetylhexosaminidase) (N-acetyl-beta-glucosaminidase) Serratia marcescens chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272] GO:0000272; GO:0004563; GO:0006032; GO:0030247; GO:0042597; GO:0102148 29926 XM_044307686.1 16 0 16 5 5 NA NA NA NA NA NA 29927 XM_044327017.1 24 0 9 3 14 NA NA NA NA NA NA 29928 XM_044316221.1 0 0 0 510 0 A2RRV3 2.86e-48 Protein PAT1 homolog 1 (PAT1-like protein 1) (Protein PAT1 homolog b) (Pat1b) Danio rerio (Zebrafish) (Brachydanio rerio) deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; P-body assembly [GO:0033962] GO:0000290; GO:0000932; GO:0003723; GO:0016605; GO:0016607; GO:0033962 29929 XM_044308702.1 0 0 83 0 109 NA NA NA NA NA NA 29930 XR_006394936.1 204 185 84 522 179 NA NA NA NA NA NA 29931 XM_044319791.1 436 249 176 428 211 NA NA NA NA NA NA 29932 XM_029335943.2 0 181 45 21 27 NA NA NA NA NA NA 29933 XM_044312750.1 0 0 0 27 0 Q17RS7 5.06e-50 Flap endonuclease GEN homolog 1 (EC 3.1.-.-) Homo sapiens (Human) double-strand break repair via homologous recombination [GO:0000724]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; regulation of centrosome duplication [GO:0010824]; replication fork processing [GO:0031297]; resolution of mitotic recombination intermediates [GO:0071140]; resolution of recombination intermediates [GO:0071139] GO:0000287; GO:0000400; GO:0000724; GO:0005654; GO:0005813; GO:0008821; GO:0010824; GO:0017108; GO:0031297; GO:0042803; GO:0071139; GO:0071140; GO:0090267 29934 XM_029331680.2 2295 2032 1553 1872 1179 Q63486 0 Ras-related GTP-binding protein A (Rag A) (RagA) (EC 3.6.5.-) Rattus norvegicus (Rat) apoptotic process [GO:0006915]; cell death [GO:0008219]; cellular response to amino acid starvation [GO:0034198]; cellular response to amino acid stimulus [GO:0071230]; cellular response to starvation [GO:0009267]; negative regulation of autophagy [GO:0010507]; negative regulation of cytolysis [GO:0045918]; positive regulation of TOR signaling [GO:0032008]; positive regulation of TORC1 signaling [GO:1904263]; protein localization [GO:0008104]; regulation of autophagy [GO:0010506]; regulation of TORC1 signaling [GO:1903432]; response to amino acid [GO:0043200]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0003924; GO:0005525; GO:0005634; GO:0005654; GO:0005737; GO:0005764; GO:0006915; GO:0008104; GO:0008219; GO:0009267; GO:0010506; GO:0010507; GO:0031625; GO:0032008; GO:0033209; GO:0034198; GO:0042803; GO:0043200; GO:0045918; GO:0046982; GO:0051219; GO:0071230; GO:1903432; GO:1904263; GO:1990130; GO:1990131 29935 XM_029357715.2 516 458 517 329 698 Q9VCA2 2.68e-95 Organic cation transporter protein Drosophila melanogaster (Fruit fly) apoptotic process [GO:0006915]; ion transport [GO:0006811] GO:0006811; GO:0006915; GO:0016020; GO:0022857 29936 XM_029340838.2 1667 731 1013 0 1607 Q96T58 3.7e-62 Msx2-interacting protein (SMART/HDAC1-associated repressor protein) (SPEN homolog) Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of neurogenesis [GO:0050769]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0003677; GO:0003714; GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0006357; GO:0007219; GO:0017053; GO:0045892; GO:0050769; GO:0061629; GO:0070062 29937 XM_029340838.2 1667 731 1013 0 1607 Q96T58 3.58e-59 Msx2-interacting protein (SMART/HDAC1-associated repressor protein) (SPEN homolog) Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of neurogenesis [GO:0050769]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0003677; GO:0003714; GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0006357; GO:0007219; GO:0017053; GO:0045892; GO:0050769; GO:0061629; GO:0070062 29938 XM_029340838.2 1667 731 1013 0 1607 Q96T58 3.35e-35 Msx2-interacting protein (SMART/HDAC1-associated repressor protein) (SPEN homolog) Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of neurogenesis [GO:0050769]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0003677; GO:0003714; GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0006357; GO:0007219; GO:0017053; GO:0045892; GO:0050769; GO:0061629; GO:0070062 29939 XM_044327560.1 62 48 9 106 353 NA NA NA NA NA NA 29940 XM_029335357.2 60 23 150 57 125 P30884 7.66e-76 Bone morphogenetic protein 2-B (BMP-2-II) Xenopus laevis (African clawed frog) cartilage development [GO:0051216]; cell differentiation [GO:0030154]; ossification [GO:0001503] GO:0001503; GO:0005125; GO:0005615; GO:0008083; GO:0030154; GO:0051216 29941 XM_044313019.1 0 0 76 49 0 P22300 3.22e-39 Gamma-aminobutyric acid receptor subunit gamma-2 (GABA(A) receptor subunit gamma-2) Bos taurus (Bovine) cellular response to histamine [GO:0071420]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid signaling pathway [GO:0007214]; inhibitory synapse assembly [GO:1904862] GO:0004890; GO:0005230; GO:0005254; GO:0005886; GO:0007214; GO:0030425; GO:0030659; GO:0034707; GO:0045211; GO:0071420; GO:1902476; GO:1902711; GO:1904862 29942 XM_044326020.1 246 46 117 97 113 Q9QZ81 4.5e-150 Protein argonaute-2 (Argonaute2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (Golgi ER protein 95 kDa) (GERp95) (Protein slicer) Rattus norvegicus (Rat) cell differentiation [GO:0030154]; miRNA metabolic process [GO:0010586]; miRNA processing [GO:0035196]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; miRNA-mediated gene silencing by mRNA destabilization [GO:0035279]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; negative regulation of translational initiation [GO:0045947]; positive regulation of angiogenesis [GO:0045766]; positive regulation of gene expression [GO:0010628]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translation, ncRNA-mediated [GO:0045975]; positive regulation of trophoblast cell migration [GO:1901165]; post-embryonic development [GO:0009791]; pre-miRNA processing [GO:0031054]; RISC complex assembly [GO:0070922]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; RNA secondary structure unwinding [GO:0010501]; RNA-mediated gene silencing [GO:0031047]; siRNA processing [GO:0030422]; siRNA-mediated gene silencing by mRNA destabilization [GO:0090625] GO:0000340; GO:0000932; GO:0000993; GO:0001046; GO:0003723; GO:0003725; GO:0003727; GO:0003729; GO:0004521; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0005844; GO:0005845; GO:0008022; GO:0009791; GO:0010501; GO:0010586; GO:0010628; GO:0016442; GO:0030154; GO:0030422; GO:0030425; GO:0031047; GO:0031054; GO:0035196; GO:0035197; GO:0035198; GO:0035278; GO:0035279; GO:0042985; GO:0045766; GO:0045944; GO:0045947; GO:0045975; GO:0046872; GO:0060213; GO:0070062; GO:0070551; GO:0070578; GO:0070922; GO:0090502; GO:0090624; GO:0090625; GO:0098808; GO:1900153; GO:1901165; GO:1990904 29943 XM_044324142.1 8 5 61 109 12 NA NA NA NA NA NA 29944 XM_029329685.2 1988 2009 1416 2224 3269 Q8BW96 1.88e-149 Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase I delta) (CaM-KI delta) (CaMKI delta) (CaM kinase ID) (CaMKI-like protein kinase) (CKLiK) (mCKLiK) Mus musculus (Mouse) inflammatory response [GO:0006954]; negative regulation of apoptotic process [GO:0043066]; nervous system development [GO:0007399]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of neuron projection development [GO:0010976]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of phagocytosis [GO:0050766]; positive regulation of respiratory burst [GO:0060267]; regulation of dendrite development [GO:0050773]; regulation of granulocyte chemotaxis [GO:0071622] GO:0004683; GO:0005516; GO:0005524; GO:0005634; GO:0005737; GO:0006954; GO:0007399; GO:0010976; GO:0018105; GO:0032793; GO:0043065; GO:0043066; GO:0050766; GO:0050773; GO:0060267; GO:0071622; GO:0090023; GO:0106310 29945 XM_029334792.2 0 0 236 320 430 E9Q7E2 3.33e-106 AT-rich interactive domain-containing protein 2 (ARID domain-containing protein 2) (BRG1-associated factor 200) (BAF200) (Zinc finger protein with activation potential) (Zipzap/p200) Mus musculus (Mouse) cardiac muscle cell proliferation [GO:0060038]; chromatin remodeling [GO:0006338]; circulatory system development [GO:0072359]; coronary artery morphogenesis [GO:0060982]; embryonic organ development [GO:0048568]; heart morphogenesis [GO:0003007]; homeostatic process [GO:0042592]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; nucleosome disassembly [GO:0006337]; positive regulation of cell differentiation [GO:0045597]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of G0 to G1 transition [GO:0070316]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of nucleotide-excision repair [GO:2000819]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000776; GO:0000785; GO:0003007; GO:0003677; GO:0005654; GO:0005667; GO:0005886; GO:0006337; GO:0006338; GO:0006357; GO:0008285; GO:0016363; GO:0016514; GO:0016586; GO:0030071; GO:0030336; GO:0042592; GO:0045582; GO:0045597; GO:0045663; GO:0045944; GO:0046872; GO:0048568; GO:0060038; GO:0060982; GO:0070316; GO:0072359; GO:1905168; GO:2000045; GO:2000781; GO:2000819 29946 XM_029343618.2 79 138 392 436 221 Q9SZJ2 3.89e-29 Glycine-rich domain-containing protein 2 (AtGRDP2) Arabidopsis thaliana (Mouse-ear cress) auxin-activated signaling pathway [GO:0009734]; cellular response to osmotic stress [GO:0071470]; regulation of auxin mediated signaling pathway [GO:0010928]; regulation of photoperiodism, flowering [GO:2000028] GO:0009734; GO:0010928; GO:0071470; GO:2000028 29947 XM_029325477.2 42 24 23 86 234 NA NA NA NA NA NA 29948 XR_006392282.1 6 0 0 4 0 NA NA NA NA NA NA 29949 XM_044318101.1 777 37 560 506 67 NA NA NA NA NA NA 29950 XM_029338340.2 1836 2001 824 1728 1058 NA NA NA NA NA NA 29951 XM_044324306.1 1752 708 1149 337 1249 Q92542 2.87e-129 Nicastrin Homo sapiens (Human) adult behavior [GO:0030534]; amyloid precursor protein biosynthetic process [GO:0042983]; amyloid precursor protein catabolic process [GO:0042987]; amyloid precursor protein metabolic process [GO:0042982]; amyloid-beta formation [GO:0034205]; cellular response to calcium ion [GO:0071277]; central nervous system myelination [GO:0022010]; cerebellum development [GO:0021549]; dopamine receptor signaling pathway [GO:0007212]; epithelial cell proliferation [GO:0050673]; glutamate receptor signaling pathway [GO:0007215]; learning or memory [GO:0007611]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; myeloid cell homeostasis [GO:0002262]; neuron apoptotic process [GO:0051402]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; positive regulation of amyloid precursor protein biosynthetic process [GO:0042986]; positive regulation of catalytic activity [GO:0043085]; positive regulation of endopeptidase activity [GO:0010950]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of long-term synaptic potentiation [GO:1900271]; short-term synaptic potentiation [GO:1990926]; T cell proliferation [GO:0042098] GO:0002262; GO:0005739; GO:0005765; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005925; GO:0006508; GO:0006509; GO:0007212; GO:0007215; GO:0007219; GO:0007220; GO:0007611; GO:0008021; GO:0010008; GO:0010950; GO:0016020; GO:0016485; GO:0021549; GO:0022010; GO:0030534; GO:0030674; GO:0031293; GO:0034205; GO:0035577; GO:0042098; GO:0042383; GO:0042470; GO:0042500; GO:0042734; GO:0042982; GO:0042983; GO:0042986; GO:0042987; GO:0043085; GO:0050673; GO:0051117; GO:0051402; GO:0070062; GO:0070765; GO:0070851; GO:0071277; GO:1900271; GO:1990926 29952 XM_044321133.1 2 2 3 2 18 Q9U6Y5 6.32e-150 GFP-like fluorescent chromoprotein FP506 (zFP506) Zoanthus sp. (Green polyp) bioluminescence [GO:0008218] GO:0008218 29953 XM_029346935.2 0 0 0 13 0 NA NA NA NA NA NA 29954 XM_029347011.2 0 6 7 9 0 NA NA NA NA NA NA 29955 XR_006392871.1 41 2 25 5 151 NA NA NA NA NA NA 29956 XM_044320181.1 3 0 0 0 18 NA NA NA NA NA NA 29957 XM_044314252.1 20 96 47 34 203 NA NA NA NA NA NA 29958 XM_029340627.2 0 0 0 0 41 Q5VXJ0 1.45e-92 Lipase member K (EC 3.1.1.-) (Lipase-like abhydrolase domain-containing protein 2) Homo sapiens (Human) cornification [GO:0070268]; lipid catabolic process [GO:0016042] GO:0004465; GO:0005576; GO:0016042; GO:0043231; GO:0070268 29959 XR_006392591.1 0 0 4 0 11 NA NA NA NA NA NA 29960 XM_044325954.1 0 0 62 39 0 Q91W86 0 Vacuolar protein sorting-associated protein 11 homolog Mus musculus (Mouse) autophagy [GO:0006914]; endosomal vesicle fusion [GO:0034058]; endosome organization [GO:0007032]; endosome to lysosome transport [GO:0008333]; intracellular protein transport [GO:0006886]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; organelle fusion [GO:0048284]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of protein catabolic process [GO:0045732]; protein ubiquitination [GO:0016567]; regulation of organelle assembly [GO:1902115]; toxin transport [GO:1901998]; vacuole organization [GO:0007033]; vesicle docking involved in exocytosis [GO:0006904] GO:0000166; GO:0005764; GO:0005765; GO:0005768; GO:0005769; GO:0005770; GO:0005776; GO:0005884; GO:0006886; GO:0006904; GO:0006914; GO:0007032; GO:0007033; GO:0008333; GO:0016567; GO:0019904; GO:0019905; GO:0030136; GO:0030139; GO:0030674; GO:0030897; GO:0031902; GO:0033147; GO:0033263; GO:0034058; GO:0045732; GO:0046872; GO:0048284; GO:0048786; GO:0061630; GO:1901998; GO:1902115; GO:2000643 29961 XM_044328127.1 667 552 674 1315 2054 NA NA NA NA NA NA 29962 XM_044315499.1 40 36 94 40 340 NA NA NA NA NA NA 29963 XM_044326108.1 0 62 12 27 2 NA NA NA NA NA NA 29964 XM_029329314.2 35 10 0 27 0 NA NA NA NA NA NA 29965 XM_044320116.1 48 0 44 30 75 NA NA NA NA NA NA 29966 XR_006393010.1 41 2 25 5 151 NA NA NA NA NA NA 29967 XM_044323355.1 20 0 3 0 6 Q9U6Y6 1.15e-111 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 29968 XM_029337859.2 100 184 114 160 181 Q6P2P2 1.63e-128 Protein arginine N-methyltransferase 9 (Protein arginine N-methyltransferase 10) (EC 2.1.1.320) Homo sapiens (Human) mRNA processing [GO:0006397]; peptidyl-arginine methylation [GO:0018216] GO:0005737; GO:0006397; GO:0016274; GO:0018216; GO:0035241; GO:0035243 29969 XR_006391725.1 9 1 0 0 0 NA NA NA NA NA NA 29970 XM_044315314.1 405 340 233 251 409 Q9CZR2 0 N-acetylated-alpha-linked acidic dipeptidase 2 (EC 3.4.17.21) (Glutamate carboxypeptidase III) (GCPIII) (N-acetylaspartylglutamate peptidase II) (NAAG-peptidase II) (N-acetylated-alpha-linked acidic dipeptidase II) (NAALADase II) Mus musculus (Mouse) neurotransmitter catabolic process [GO:0042135]; proteolysis [GO:0006508] GO:0004180; GO:0004181; GO:0005886; GO:0006508; GO:0008233; GO:0016020; GO:0016805; GO:0042135; GO:0046872; GO:0050129 29971 XM_029348702.2 755 599 922 504 909 Q9D787 0 RING-type E3 ubiquitin-protein ligase PPIL2 (EC 2.3.2.27) (CYC4) (Probable inactive peptidyl-prolyl cis-trans isomerase-like 2) (PPIase) Mus musculus (Mouse) protein folding [GO:0006457]; protein localization to plasma membrane [GO:0072659]; protein peptidyl-prolyl isomerization [GO:0000413]; protein polyubiquitination [GO:0000209] GO:0000209; GO:0000413; GO:0003755; GO:0004842; GO:0005634; GO:0005654; GO:0005737; GO:0005886; GO:0006457; GO:0034450; GO:0061630; GO:0071013; GO:0072659 29972 XM_029357046.2 0 0 3 0 13 NA NA NA NA NA NA 29973 XM_029357180.2 20 39 18 40 8 NA NA NA NA NA NA 29974 XM_029347659.2 150 36 396 129 218 Q0EEE2 4.66e-68 Patched domain-containing protein 3 (RND-type protein RNDEu-3) Mus musculus (Mouse) NA GO:0005783; GO:0005789; GO:0005886; GO:0016020; GO:0097225 29975 XM_029330569.2 793 553 220 438 235 A0A3Q2HW92 9.24e-119 Major facilitator superfamily domain-containing protein 12 Equus caballus (Horse) carbohydrate transport [GO:0008643]; cysteine transmembrane transport [GO:1903712]; melanin biosynthetic process [GO:0042438]; negative regulation of melanin biosynthetic process [GO:0048022]; pigment metabolic process involved in pigmentation [GO:0043474] GO:0005764; GO:0005765; GO:0005770; GO:0008643; GO:0015293; GO:0033162; GO:0033229; GO:0042438; GO:0043474; GO:0048022; GO:1903712 29976 XM_029357659.2 0 0 19 0 112 P48733 1e-28 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Bos taurus (Bovine) antibacterial innate immune response [GO:0140367]; defense response to Gram-negative bacterium [GO:0050829] GO:0000922; GO:0005201; GO:0005509; GO:0005576; GO:0005929; GO:0016020; GO:0016323; GO:0016324; GO:0031012; GO:0050829; GO:0060170; GO:0140367 29977 XM_029336050.2 395 308 166 307 345 NA NA NA NA NA NA 29978 XM_044328386.1 6 9 2 6 489 Q9BX70 7.03e-73 BTB/POZ domain-containing protein 2 Homo sapiens (Human) neurogenesis [GO:0022008] GO:0000932; GO:0005829; GO:0022008 29979 XM_029330366.2 1723 1501 675 1553 1138 Q9P289 2.92e-153 Serine/threonine-protein kinase 26 (EC 2.7.11.1) (MST3 and SOK1-related kinase) (Mammalian STE20-like protein kinase 4) (MST-4) (STE20-like kinase MST4) (Serine/threonine-protein kinase MASK) Homo sapiens (Human) apoptotic process [GO:0006915]; cellular response to starvation [GO:0009267]; microvillus assembly [GO:0030033]; negative regulation of cell migration [GO:0030336]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; response to hydrogen peroxide [GO:0042542] GO:0000287; GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0005794; GO:0005798; GO:0005829; GO:0006468; GO:0006915; GO:0009267; GO:0012506; GO:0016020; GO:0016324; GO:0030033; GO:0030336; GO:0042542; GO:0042802; GO:0042803; GO:0042981; GO:0046777; GO:0048471; GO:0070062; GO:0071944; GO:0106310; GO:1903205 29980 XM_044315047.1 2 0 0 5 13 NA NA NA NA NA NA 29981 XR_003825953.1 41 2 25 5 151 NA NA NA NA NA NA 29982 XR_006391609.1 19 1 38 7 159 NA NA NA NA NA NA 29983 XM_044307842.1 1726 1800 912 1525 1064 Q2KIL7 1.45e-29 R3H domain-containing protein 4 Bos taurus (Bovine) NA GO:0003676; GO:0005634 29984 XM_029325409.2 147 53 87 166 190 NA NA NA NA NA NA 29985 XM_029337490.2 33 0 0 0 0 O09118 0 Netrin-1 Mus musculus (Mouse) animal organ morphogenesis [GO:0009887]; anterior/posterior axon guidance [GO:0033564]; apoptotic process [GO:0006915]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; B cell mediated immunity [GO:0019724]; B cell proliferation [GO:0042100]; Cdc42 protein signal transduction [GO:0032488]; cell population proliferation [GO:0008283]; cell-cell adhesion [GO:0098609]; chemorepulsion of axon [GO:0061643]; dendrite development [GO:0016358]; glial cell proliferation [GO:0014009]; inner ear morphogenesis [GO:0042472]; mammary gland development [GO:0030879]; mammary gland duct morphogenesis [GO:0060603]; motor neuron axon guidance [GO:0008045]; motor neuron migration [GO:0097475]; negative regulation of axon extension [GO:0030517]; neuron migration [GO:0001764]; nuclear migration [GO:0007097]; positive regulation of axon extension [GO:0045773]; positive regulation of cell motility [GO:2000147]; positive regulation of glial cell proliferation [GO:0060252]; Ras protein signal transduction [GO:0007265]; regulation of cell migration [GO:0030334]; regulation of glial cell migration [GO:1903975]; regulation of synapse assembly [GO:0051963]; substrate-dependent cell migration, cell extension [GO:0006930]; T cell mediated immunity [GO:0002456]; tissue development [GO:0009888] GO:0001764; GO:0002456; GO:0005125; GO:0005576; GO:0005604; GO:0005654; GO:0005737; GO:0005829; GO:0006915; GO:0006930; GO:0007097; GO:0007265; GO:0007409; GO:0007411; GO:0008045; GO:0008283; GO:0009887; GO:0009888; GO:0014009; GO:0015629; GO:0016358; GO:0019724; GO:0030334; GO:0030517; GO:0030879; GO:0031012; GO:0032488; GO:0033564; GO:0042100; GO:0042472; GO:0045773; GO:0051963; GO:0060252; GO:0060603; GO:0061643; GO:0062023; GO:0071944; GO:0097475; GO:0098609; GO:1903975; GO:2000147 29986 XM_029358692.2 340 219 162 94 61 Q99L13 1.86e-122 3-hydroxyisobutyrate dehydrogenase, mitochondrial (HIBADH) (EC 1.1.1.31) Mus musculus (Mouse) valine catabolic process [GO:0006574] GO:0005739; GO:0006574; GO:0008442; GO:0016616; GO:0050661; GO:0051287 29987 XM_029340387.2 0 100 100 31 0 E9QAT4 1.15e-45 Protein transport protein Sec16A (SEC16 homolog A) (p250) Mus musculus (Mouse) autophagy [GO:0006914]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; Golgi to plasma membrane transport [GO:0006893]; protein exit from endoplasmic reticulum [GO:0032527]; protein localization to endoplasmic reticulum exit site [GO:0070973]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; response to endoplasmic reticulum stress [GO:0034976] GO:0000139; GO:0005789; GO:0005829; GO:0006888; GO:0006893; GO:0006914; GO:0007029; GO:0007030; GO:0012507; GO:0031090; GO:0032527; GO:0034976; GO:0048208; GO:0048471; GO:0050821; GO:0070971; GO:0070973; GO:0072659 29988 XM_029336342.2 206 157 171 270 210 NA NA NA NA NA NA 29989 XM_044307979.1 261 513 170 511 383 Q4UMH6 2.49e-40 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 29990 XM_044307979.1 261 513 170 511 383 Q4UMH6 1.64e-38 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 29991 XM_044307979.1 261 513 170 511 383 Q4UMH6 2.35e-31 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 29992 XM_044307979.1 261 513 170 511 383 Q4UMH6 1.22e-30 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 29993 XM_044307979.1 261 513 170 511 383 Q4UMH6 1.33e-29 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 29994 XM_044307979.1 261 513 170 511 383 Q4UMH6 5.81e-29 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 29995 XM_044313387.1 4617 2776 4387 7147 6203 NA NA NA NA NA NA 29996 XM_044323263.1 250 447 93 1127 924 NA NA NA NA NA NA 29997 XM_029350544.2 600 354 34 32 71 NA NA NA NA NA NA 29998 XR_006393798.1 29 34 56 30 35 NA NA NA NA NA NA 29999 XM_029345075.2 2 30 28 2 33 P58912 2.21e-81 DELTA-alicitoxin-Pse2b (DELTA-ALTX-Pse2b) (Toxin PsTX-60B) (PTX60B) Phyllodiscus semoni (Night anemone) hemolysis in another organism [GO:0044179] GO:0005576; GO:0042151; GO:0044179; GO:0090729 30000 XM_044308037.1 0 0 6 11 17 NA NA NA NA NA NA 30001 XM_044317754.1 76 41 43 12 41 NA NA NA NA NA NA 30002 XM_044319778.1 63 39 55 69 62 NA NA NA NA NA NA 30003 XM_044316916.1 279 141 280 424 359 Q14202 1.38e-29 Zinc finger MYM-type protein 3 (Zinc finger protein 261) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; regulation of cell morphogenesis [GO:0022604] GO:0003677; GO:0005654; GO:0007010; GO:0008270; GO:0022604 30004 XM_029331241.2 41 493 0 0 0 Q924D0 2.74e-97 Reticulon-4-interacting protein 1, mitochondrial (NOGO-interacting mitochondrial protein) Mus musculus (Mouse) nervous system development [GO:0007399]; regulation of dendrite development [GO:0050773] GO:0005739; GO:0005741; GO:0007399; GO:0008270; GO:0016491; GO:0050773 30005 XR_006396531.1 161 158 140 230 218 NA NA NA NA NA NA 30006 XM_029323560.2 1015 689 606 849 953 P53492 1.42e-57 Actin-7 (EC 3.6.4.-) (Actin-2) Arabidopsis thaliana (Mouse-ear cress) cell division [GO:0051301]; Golgi to plasma membrane transport [GO:0006893]; protein localization [GO:0008104]; protein transport [GO:0015031]; response to auxin [GO:0009733]; response to light stimulus [GO:0009416]; response to wounding [GO:0009611]; root development [GO:0048364]; root epidermal cell differentiation [GO:0010053]; root hair elongation [GO:0048767]; seed germination [GO:0009845] GO:0005200; GO:0005524; GO:0005730; GO:0005739; GO:0005829; GO:0005856; GO:0005886; GO:0006893; GO:0008104; GO:0009416; GO:0009505; GO:0009506; GO:0009570; GO:0009611; GO:0009733; GO:0009845; GO:0009941; GO:0010053; GO:0015031; GO:0016787; GO:0048364; GO:0048767; GO:0051301 30007 XM_044325679.1 145 167 154 378 319 NA NA NA NA NA NA 30008 XR_006394745.1 0 44 41 0 61 NA NA NA NA NA NA 30009 XM_029348808.2 313 271 154 225 263 Q5HZP1 3.18e-64 Ribonuclease H2 subunit B (RNase H2 subunit B) (Ribonuclease HI subunit B) Xenopus laevis (African clawed frog) RNA catabolic process [GO:0006401] GO:0005634; GO:0006401; GO:0032299 30010 XM_044310792.1 123 62 111 64 152 NA NA NA NA NA NA 30011 XM_044310316.1 506 154 366 359 1026 NA NA NA NA NA NA 30012 XM_044310279.1 36 0 0 33 0 NA NA NA NA NA NA 30013 XM_044308383.1 303 194 54 246 225 Q9HCS5 5.51e-108 Band 4.1-like protein 4A (Erythrocyte membrane protein band 4.1-like 4A) (Protein NBL4) Homo sapiens (Human) actomyosin structure organization [GO:0031032] GO:0005737; GO:0005856; GO:0008092; GO:0031032 30014 XM_044322722.1 129 60 106 23 92 Q8CBF3 2.66e-160 Ephrin type-B receptor 1 (EC 2.7.10.1) Mus musculus (Mouse) angiogenesis [GO:0001525]; axon guidance [GO:0007411]; camera-type eye morphogenesis [GO:0048593]; cell chemotaxis [GO:0060326]; cell-substrate adhesion [GO:0031589]; central nervous system projection neuron axonogenesis [GO:0021952]; cranial nerve development [GO:0021545]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; ephrin receptor signaling pathway [GO:0048013]; establishment of cell polarity [GO:0030010]; hindbrain tangential cell migration [GO:0021934]; immunological synapse formation [GO:0001771]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of satellite cell differentiation [GO:1902725]; negative regulation of skeletal muscle satellite cell proliferation [GO:1902723]; neural precursor cell proliferation [GO:0061351]; neurogenesis [GO:0022008]; optic nerve morphogenesis [GO:0021631]; positive regulation of kinase activity [GO:0033674]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of neuron death [GO:1901214]; retinal ganglion cell axon guidance [GO:0031290]; skeletal muscle satellite cell activation [GO:0014719]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0001525; GO:0001771; GO:0004713; GO:0004714; GO:0005005; GO:0005524; GO:0005737; GO:0005783; GO:0005829; GO:0005886; GO:0007169; GO:0007411; GO:0008046; GO:0014719; GO:0016020; GO:0021545; GO:0021631; GO:0021934; GO:0021952; GO:0022008; GO:0030010; GO:0030424; GO:0030425; GO:0031290; GO:0031589; GO:0031901; GO:0032433; GO:0033674; GO:0043005; GO:0043235; GO:0044877; GO:0045121; GO:0046328; GO:0046777; GO:0048013; GO:0048593; GO:0050804; GO:0050965; GO:0051965; GO:0060326; GO:0060996; GO:0060997; GO:0061351; GO:0070372; GO:0098978; GO:1901214; GO:1902723; GO:1902725 30015 XM_044308255.1 15 5 14 4 0 NA NA NA NA NA NA 30016 XM_029325730.2 4290 3346 3000 3623 4067 O46037 0 Vinculin Drosophila melanogaster (Fruit fly) cell adhesion [GO:0007155] GO:0005198; GO:0005737; GO:0005856; GO:0005886; GO:0005912; GO:0005925; GO:0007155; GO:0008013; GO:0015629; GO:0044291; GO:0045294; GO:0051015; GO:0098592 30017 XM_044312963.1 2 5 66 9 11 NA NA NA NA NA NA 30018 XM_044310994.1 145 947 507 826 1199 NA NA NA NA NA NA 30019 XM_029335539.2 87 188 44 102 156 NA NA NA NA NA NA 30020 XM_044309669.1 8 2 10 19 42 O16025 0 Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (AOS) (EC 4.2.1.-) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)] Plexaura homomalla (Black sea rod) arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; lipid oxidation [GO:0034440]; oxylipin biosynthetic process [GO:0031408] GO:0005506; GO:0005737; GO:0006633; GO:0009978; GO:0016020; GO:0019369; GO:0020037; GO:0031408; GO:0034440; GO:0047677 30021 XM_029324161.2 35 0 26 7 137 NA NA NA NA NA NA 30022 XR_006392415.1 18 9 4 11 14 NA NA NA NA NA NA 30023 XM_029331596.2 533 309 183 322 487 Q9BSR8 2.98e-57 Protein YIPF4 (YIP1 family member 4) Homo sapiens (Human) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; vesicle fusion with Golgi apparatus [GO:0048280] GO:0005783; GO:0005794; GO:0005802; GO:0005886; GO:0006888; GO:0043231; GO:0048280 30024 XM_044325604.1 44 12 25 2 114 B8VIU6 1.6e-55 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 30025 XM_044314853.1 340 313 164 409 404 O96017 6.53e-157 Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2) Homo sapiens (Human) cell division [GO:0051301]; cellular response to bisphenol A [GO:1903926]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage checkpoint signaling [GO:0000077]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; double-strand break repair [GO:0006302]; G2/M transition of mitotic cell cycle [GO:0000086]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; mitotic DNA damage checkpoint signaling [GO:0044773]; mitotic intra-S DNA damage checkpoint signaling [GO:0031573]; mitotic spindle assembly [GO:0090307]; negative regulation of DNA damage checkpoint [GO:2000002]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of anoikis [GO:2000210]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of protein phosphorylation [GO:0001934]; protein autophosphorylation [GO:0046777]; protein catabolic process [GO:0030163]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of DNA-templated transcription [GO:0006355]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction by p53 class mediator [GO:1901796]; replicative senescence [GO:0090399]; response to glycoside [GO:1903416]; signal transduction in response to DNA damage [GO:0042770]; thymocyte apoptotic process [GO:0070242] GO:0000077; GO:0000086; GO:0001934; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005794; GO:0006302; GO:0006355; GO:0006468; GO:0006974; GO:0006977; GO:0006978; GO:0008630; GO:0016605; GO:0018105; GO:0019901; GO:0030163; GO:0031573; GO:0031625; GO:0042176; GO:0042770; GO:0042771; GO:0042802; GO:0042803; GO:0044773; GO:0045893; GO:0046777; GO:0046872; GO:0050821; GO:0051301; GO:0070242; GO:0071466; GO:0071480; GO:0090307; GO:0090399; GO:0106310; GO:1901796; GO:1903416; GO:1903926; GO:2000002; GO:2000210 30026 XM_044314977.1 11 3 18 4 16 NA NA NA NA NA NA 30027 XM_044326253.1 72 36 111 157 179 Q6PDJ1 3.91e-81 VWFA and cache domain-containing protein 1 (Cache domain-containing protein 1) Mus musculus (Mouse) NA GO:0005245; GO:0005891 30028 XM_044326253.1 72 36 111 157 179 Q6PDJ1 2.26e-48 VWFA and cache domain-containing protein 1 (Cache domain-containing protein 1) Mus musculus (Mouse) NA GO:0005245; GO:0005891 30029 XM_029349493.2 16212 10097 3413 8208 2626 Q8WV99 3.6e-27 AN1-type zinc finger protein 2B (Arsenite-inducible RNA-associated protein-like protein) (AIRAP-like protein) Homo sapiens (Human) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein targeting to ER [GO:0045047]; regulation of insulin-like growth factor receptor signaling pathway [GO:0043567]; SRP-dependent cotranslational protein targeting to membrane, translocation [GO:0006616] GO:0000502; GO:0005737; GO:0005783; GO:0005789; GO:0006616; GO:0008270; GO:0016020; GO:0036435; GO:0043130; GO:0043161; GO:0043567; GO:0045047 30030 XM_029338190.2 0 23 66 104 26 P24409 3.34e-32 Ras-related protein Rab-10 (EC 3.6.5.2) Canis lupus familiaris (Dog) (Canis familiaris) axonogenesis [GO:0007409]; cellular response to insulin stimulus [GO:0032869]; endosomal transport [GO:0016197]; establishment of neuroblast polarity [GO:0045200]; Golgi to plasma membrane protein transport [GO:0043001]; Golgi to plasma membrane transport [GO:0006893]; polarized epithelial cell differentiation [GO:0030859]; protein localization to basolateral plasma membrane [GO:1903361]; protein localization to plasma membrane [GO:0072659]; protein secretion [GO:0009306]; regulation of exocytosis [GO:0017157]; vesicle docking involved in exocytosis [GO:0006904]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0003924; GO:0003925; GO:0005525; GO:0005768; GO:0005789; GO:0005794; GO:0005802; GO:0005886; GO:0005929; GO:0006893; GO:0006904; GO:0007409; GO:0008021; GO:0009306; GO:0016192; GO:0016197; GO:0017157; GO:0019003; GO:0030670; GO:0030859; GO:0031489; GO:0032593; GO:0032869; GO:0043001; GO:0043231; GO:0045200; GO:0055037; GO:0055038; GO:0072659; GO:1903361 30031 XM_044317343.1 474 282 67 316 319 Q0P4P2 2.63e-69 Fibrinogen C domain-containing protein 1 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0008061; GO:0016020; GO:0046872 30032 XR_006393527.1 46 151 54 165 111 NA NA NA NA NA NA 30033 XM_029326722.2 6 1 0 0 3 NA NA NA NA NA NA 30034 XM_029329168.2 9148 14143 7477 11291 9502 P17074 1.44e-42 40S ribosomal protein S19 Rattus norvegicus (Rat) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response to Gram-negative bacterium [GO:0050829]; erythrocyte differentiation [GO:0030218]; killing of cells of another organism [GO:0031640]; maturation of SSU-rRNA [GO:0030490]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; monocyte chemotaxis [GO:0002548]; negative regulation of respiratory burst involved in inflammatory response [GO:0060266]; Notch signaling pathway [GO:0007219]; nucleolus organization [GO:0007000]; positive regulation of respiratory burst involved in inflammatory response [GO:0060265]; ribosomal small subunit assembly [GO:0000028]; ribosomal small subunit biogenesis [GO:0042274]; rRNA processing [GO:0006364]; translation [GO:0006412] GO:0000028; GO:0000462; GO:0002548; GO:0003723; GO:0003735; GO:0005730; GO:0005737; GO:0005829; GO:0005840; GO:0006364; GO:0006412; GO:0007000; GO:0007219; GO:0014069; GO:0015935; GO:0017134; GO:0019901; GO:0022626; GO:0022627; GO:0030218; GO:0030490; GO:0031369; GO:0031640; GO:0042274; GO:0042802; GO:0045202; GO:0050829; GO:0060265; GO:0060266; GO:0061844 30035 XM_029342396.2 3169 2665 2054 3108 3884 Q3UZV7 0 Endosome/lysosome-associated apoptosis and autophagy regulator family member 2 (Estrogen-induced gene 121-like protein) Mus musculus (Mouse) negative regulation of nervous system development [GO:0051961]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of epidermis development [GO:0045684] GO:0005886; GO:0016020; GO:0030513; GO:0045684; GO:0051961; GO:0070700 30036 XM_044307542.1 571 0 0 0 195 Q8R418 6.19e-165 Endoribonuclease Dicer (EC 3.1.26.3) (Double-strand-specific ribonuclease mDCR-1) Mus musculus (Mouse) anatomical structure development [GO:0048856]; angiogenesis [GO:0001525]; apoptotic DNA fragmentation [GO:0006309]; branching morphogenesis of an epithelial tube [GO:0048754]; cardiac muscle cell development [GO:0055013]; cardiac neural crest cell development involved in outflow tract morphogenesis [GO:0061309]; cartilage development [GO:0051216]; cell population proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; defense response to virus [GO:0051607]; digestive tract development [GO:0048565]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; epidermis morphogenesis [GO:0048730]; ganglion development [GO:0061548]; gene expression [GO:0010467]; global gene silencing by mRNA cleavage [GO:0098795]; hair follicle cell proliferation [GO:0071335]; hair follicle development [GO:0001942]; hair follicle morphogenesis [GO:0031069]; inner ear receptor cell development [GO:0060119]; intestinal epithelial cell development [GO:0060576]; lung development [GO:0030324]; meiotic spindle organization [GO:0000212]; miRNA processing [GO:0035196]; mRNA stabilization [GO:0048255]; multicellular organism growth [GO:0035264]; myoblast differentiation involved in skeletal muscle regeneration [GO:0014835]; negative regulation of gene expression [GO:0010629]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of Schwann cell proliferation [GO:0010626]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of tumor necrosis factor production [GO:0032720]; nerve development [GO:0021675]; neuron projection morphogenesis [GO:0048812]; NIK/NF-kappaB signaling [GO:0038061]; olfactory bulb interneuron differentiation [GO:0021889]; pericentric heterochromatin formation [GO:0031508]; peripheral nervous system myelin formation [GO:0032290]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904906]; positive regulation of establishment of endothelial barrier [GO:1903142]; positive regulation of gene expression [GO:0010628]; positive regulation of hepatic stellate cell proliferation [GO:1904899]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of myelination [GO:0031643]; positive regulation of Schwann cell differentiation [GO:0014040]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; post-embryonic development [GO:0009791]; pre-miRNA processing [GO:0031054]; regulation of cell cycle [GO:0051726]; regulation of enamel mineralization [GO:0070173]; regulation of epithelial cell differentiation [GO:0030856]; regulation of gene expression [GO:0010468]; regulation of inflammatory response [GO:0050727]; regulation of miRNA metabolic process [GO:2000628]; regulation of muscle cell apoptotic process [GO:0010660]; regulation of myelination [GO:0031641]; regulation of neurogenesis [GO:0050767]; regulation of neuron differentiation [GO:0045664]; regulation of Notch signaling pathway [GO:0008593]; regulation of odontogenesis of dentin-containing tooth [GO:0042487]; regulation of oligodendrocyte differentiation [GO:0048713]; regulation of protein phosphorylation [GO:0001932]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of RNA metabolic process [GO:0051252]; regulation of stem cell differentiation [GO:2000736]; regulation of viral genome replication [GO:0045069]; reproductive structure development [GO:0048608]; RISC complex assembly [GO:0070922]; RNA phosphodiester bond hydrolysis [GO:0090501]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; RNA processing [GO:0006396]; RNA-mediated post-transcriptional gene silencing [GO:0035194]; rRNA processing [GO:0006364]; siRNA processing [GO:0030422]; spermatogonial cell division [GO:0007284]; spinal cord motor neuron differentiation [GO:0021522]; spindle assembly [GO:0051225]; spleen development [GO:0048536]; stem cell population maintenance [GO:0019827]; trophectodermal cell proliferation [GO:0001834]; zygote asymmetric cell division [GO:0010070] GO:0000122; GO:0000212; GO:0001525; GO:0001834; GO:0001932; GO:0001942; GO:0003677; GO:0003723; GO:0003725; GO:0004386; GO:0004521; GO:0004525; GO:0004530; GO:0005524; GO:0005634; GO:0005737; GO:0005783; GO:0005793; GO:0005829; GO:0006309; GO:0006364; GO:0006396; GO:0007284; GO:0008283; GO:0008593; GO:0009791; GO:0010070; GO:0010467; GO:0010468; GO:0010595; GO:0010626; GO:0010628; GO:0010629; GO:0010660; GO:0014040; GO:0014835; GO:0016442; GO:0019827; GO:0019904; GO:0021522; GO:0021675; GO:0021889; GO:0021987; GO:0030324; GO:0030326; GO:0030422; GO:0030424; GO:0030425; GO:0030426; GO:0030856; GO:0031054; GO:0031069; GO:0031508; GO:0031641; GO:0031643; GO:0032290; GO:0032720; GO:0032967; GO:0035116; GO:0035194; GO:0035196; GO:0035197; GO:0035198; GO:0035264; GO:0038061; GO:0042487; GO:0045069; GO:0045589; GO:0045664; GO:0045944; GO:0046872; GO:0048255; GO:0048471; GO:0048536; GO:0048565; GO:0048608; GO:0048713; GO:0048730; GO:0048754; GO:0048812; GO:0048856; GO:0050727; GO:0050767; GO:0051216; GO:0051225; GO:0051252; GO:0051607; GO:0051726; GO:0055013; GO:0060119; GO:0060253; GO:0060576; GO:0061309; GO:0061548; GO:0070062; GO:0070173; GO:0070578; GO:0070883; GO:0070922; GO:0071335; GO:0090501; GO:0090502; GO:0098795; GO:0098978; GO:0099092; GO:1903142; GO:1904899; GO:1904906; GO:1905564; GO:2000628; GO:2000630; GO:2000736 30037 XM_044307542.1 571 0 0 0 195 Q8R418 1.29e-66 Endoribonuclease Dicer (EC 3.1.26.3) (Double-strand-specific ribonuclease mDCR-1) Mus musculus (Mouse) anatomical structure development [GO:0048856]; angiogenesis [GO:0001525]; apoptotic DNA fragmentation [GO:0006309]; branching morphogenesis of an epithelial tube [GO:0048754]; cardiac muscle cell development [GO:0055013]; cardiac neural crest cell development involved in outflow tract morphogenesis [GO:0061309]; cartilage development [GO:0051216]; cell population proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; defense response to virus [GO:0051607]; digestive tract development [GO:0048565]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; epidermis morphogenesis [GO:0048730]; ganglion development [GO:0061548]; gene expression [GO:0010467]; global gene silencing by mRNA cleavage [GO:0098795]; hair follicle cell proliferation [GO:0071335]; hair follicle development [GO:0001942]; hair follicle morphogenesis [GO:0031069]; inner ear receptor cell development [GO:0060119]; intestinal epithelial cell development [GO:0060576]; lung development [GO:0030324]; meiotic spindle organization [GO:0000212]; miRNA processing [GO:0035196]; mRNA stabilization [GO:0048255]; multicellular organism growth [GO:0035264]; myoblast differentiation involved in skeletal muscle regeneration [GO:0014835]; negative regulation of gene expression [GO:0010629]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of Schwann cell proliferation [GO:0010626]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of tumor necrosis factor production [GO:0032720]; nerve development [GO:0021675]; neuron projection morphogenesis [GO:0048812]; NIK/NF-kappaB signaling [GO:0038061]; olfactory bulb interneuron differentiation [GO:0021889]; pericentric heterochromatin formation [GO:0031508]; peripheral nervous system myelin formation [GO:0032290]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904906]; positive regulation of establishment of endothelial barrier [GO:1903142]; positive regulation of gene expression [GO:0010628]; positive regulation of hepatic stellate cell proliferation [GO:1904899]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of myelination [GO:0031643]; positive regulation of Schwann cell differentiation [GO:0014040]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; post-embryonic development [GO:0009791]; pre-miRNA processing [GO:0031054]; regulation of cell cycle [GO:0051726]; regulation of enamel mineralization [GO:0070173]; regulation of epithelial cell differentiation [GO:0030856]; regulation of gene expression [GO:0010468]; regulation of inflammatory response [GO:0050727]; regulation of miRNA metabolic process [GO:2000628]; regulation of muscle cell apoptotic process [GO:0010660]; regulation of myelination [GO:0031641]; regulation of neurogenesis [GO:0050767]; regulation of neuron differentiation [GO:0045664]; regulation of Notch signaling pathway [GO:0008593]; regulation of odontogenesis of dentin-containing tooth [GO:0042487]; regulation of oligodendrocyte differentiation [GO:0048713]; regulation of protein phosphorylation [GO:0001932]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of RNA metabolic process [GO:0051252]; regulation of stem cell differentiation [GO:2000736]; regulation of viral genome replication [GO:0045069]; reproductive structure development [GO:0048608]; RISC complex assembly [GO:0070922]; RNA phosphodiester bond hydrolysis [GO:0090501]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; RNA processing [GO:0006396]; RNA-mediated post-transcriptional gene silencing [GO:0035194]; rRNA processing [GO:0006364]; siRNA processing [GO:0030422]; spermatogonial cell division [GO:0007284]; spinal cord motor neuron differentiation [GO:0021522]; spindle assembly [GO:0051225]; spleen development [GO:0048536]; stem cell population maintenance [GO:0019827]; trophectodermal cell proliferation [GO:0001834]; zygote asymmetric cell division [GO:0010070] GO:0000122; GO:0000212; GO:0001525; GO:0001834; GO:0001932; GO:0001942; GO:0003677; GO:0003723; GO:0003725; GO:0004386; GO:0004521; GO:0004525; GO:0004530; GO:0005524; GO:0005634; GO:0005737; GO:0005783; GO:0005793; GO:0005829; GO:0006309; GO:0006364; GO:0006396; GO:0007284; GO:0008283; GO:0008593; GO:0009791; GO:0010070; GO:0010467; GO:0010468; GO:0010595; GO:0010626; GO:0010628; GO:0010629; GO:0010660; GO:0014040; GO:0014835; GO:0016442; GO:0019827; GO:0019904; GO:0021522; GO:0021675; GO:0021889; GO:0021987; GO:0030324; GO:0030326; GO:0030422; GO:0030424; GO:0030425; GO:0030426; GO:0030856; GO:0031054; GO:0031069; GO:0031508; GO:0031641; GO:0031643; GO:0032290; GO:0032720; GO:0032967; GO:0035116; GO:0035194; GO:0035196; GO:0035197; GO:0035198; GO:0035264; GO:0038061; GO:0042487; GO:0045069; GO:0045589; GO:0045664; GO:0045944; GO:0046872; GO:0048255; GO:0048471; GO:0048536; GO:0048565; GO:0048608; GO:0048713; GO:0048730; GO:0048754; GO:0048812; GO:0048856; GO:0050727; GO:0050767; GO:0051216; GO:0051225; GO:0051252; GO:0051607; GO:0051726; GO:0055013; GO:0060119; GO:0060253; GO:0060576; GO:0061309; GO:0061548; GO:0070062; GO:0070173; GO:0070578; GO:0070883; GO:0070922; GO:0071335; GO:0090501; GO:0090502; GO:0098795; GO:0098978; GO:0099092; GO:1903142; GO:1904899; GO:1904906; GO:1905564; GO:2000628; GO:2000630; GO:2000736 30038 XR_006396517.1 1 0 4 10 12 NA NA NA NA NA NA 30039 XR_006394969.1 221 7 79 82 90 NA NA NA NA NA NA 30040 XM_044320384.1 207 114 120 684 151 NA NA NA NA NA NA 30041 XR_006398147.1 23 31 5 4 18 NA NA NA NA NA NA 30042 XM_044316805.1 35 4 0 0 5 NA NA NA NA NA NA 30043 XM_029342211.2 75 302 414 38 264 Q32PD8 8.04e-40 Leptin receptor overlapping transcript-like 1 Bos taurus (Bovine) late endosome to vacuole transport via multivesicular body sorting pathway [GO:0032511]; negative regulation of growth hormone receptor signaling pathway [GO:0060400] GO:0005768; GO:0016020; GO:0032511; GO:0060400 30044 XM_044320267.1 357 619 206 395 464 Q28CH8 5.86e-97 Protein YIPF6 (YIP1 family member 6) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888] GO:0000138; GO:0000139; GO:0005797; GO:0005802; GO:0006888 30045 XM_029324134.2 113 97 96 195 203 Q6UWP7 3.39e-101 Lysocardiolipin acyltransferase 1 (EC 2.3.1.-) (1-acylglycerol-3-phosphate O-acyltransferase 8) (1-AGP acyltransferase 8) (1-AGPAT 8) (EC 2.3.1.51) (Acyl-CoA:lysocardiolipin acyltransferase 1) Homo sapiens (Human) cardiolipin acyl-chain remodeling [GO:0035965]; CDP-diacylglycerol biosynthetic process [GO:0016024]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidylinositol acyl-chain remodeling [GO:0036149] GO:0003841; GO:0005783; GO:0005789; GO:0005829; GO:0006654; GO:0008374; GO:0012505; GO:0016020; GO:0016024; GO:0016746; GO:0035965; GO:0036149 30046 XM_029331270.2 170 110 81 172 112 Q5F2N3 9.24e-26 Alpha-(1,3)-fucosyltransferase 10 (EC 2.4.1.-) (Fucosyltransferase X) (Fuc-TX) (FucT-X) (Galactoside 3-L-fucosyltransferase 10) (Fucosyltransferase 10) Danio rerio (Zebrafish) (Brachydanio rerio) fucosylation [GO:0036065]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0032580; GO:0036065; GO:0046920 30047 XM_044307525.1 17 26 9 33 136 Q8C0T9 5.49e-77 Adenylate cyclase type 10 (EC 4.6.1.1) (Germ cell soluble adenylyl cyclase) (sAC) (Testicular soluble adenylyl cyclase) Mus musculus (Mouse) cAMP biosynthetic process [GO:0006171]; cellular response to inorganic substance [GO:0071241]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; intracellular signal transduction [GO:0035556]; positive regulation of apoptotic process [GO:0043065]; spermatogenesis [GO:0007283] GO:0000287; GO:0003351; GO:0004016; GO:0005524; GO:0005576; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0006171; GO:0007283; GO:0015630; GO:0016020; GO:0016324; GO:0030145; GO:0030424; GO:0030425; GO:0030426; GO:0031514; GO:0035556; GO:0043025; GO:0043065; GO:0045177; GO:0045178; GO:0048471; GO:0051117; GO:0071241; GO:0071890 30048 XM_044307525.1 17 26 9 33 136 Q8C0T9 8.66e-27 Adenylate cyclase type 10 (EC 4.6.1.1) (Germ cell soluble adenylyl cyclase) (sAC) (Testicular soluble adenylyl cyclase) Mus musculus (Mouse) cAMP biosynthetic process [GO:0006171]; cellular response to inorganic substance [GO:0071241]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; intracellular signal transduction [GO:0035556]; positive regulation of apoptotic process [GO:0043065]; spermatogenesis [GO:0007283] GO:0000287; GO:0003351; GO:0004016; GO:0005524; GO:0005576; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0006171; GO:0007283; GO:0015630; GO:0016020; GO:0016324; GO:0030145; GO:0030424; GO:0030425; GO:0030426; GO:0031514; GO:0035556; GO:0043025; GO:0043065; GO:0045177; GO:0045178; GO:0048471; GO:0051117; GO:0071241; GO:0071890 30049 XM_029351585.2 4177 3664 2322 4716 5696 P55010 1.55e-137 Eukaryotic translation initiation factor 5 (eIF-5) Homo sapiens (Human) formation of cytoplasmic translation initiation complex [GO:0001732]; formation of translation preinitiation complex [GO:0001731]; regulation of translational initiation [GO:0006446] GO:0001731; GO:0001732; GO:0003723; GO:0003743; GO:0005092; GO:0005525; GO:0005737; GO:0005829; GO:0005886; GO:0006446; GO:0045202; GO:0045296; GO:0071074 30050 XM_044323168.1 0 108 107 176 323 NA NA NA NA NA NA 30051 XM_029336581.2 1616 1059 798 1337 1177 Q8BXK8 2.82e-118 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 (AGAP-1) (Centaurin-gamma-2) (Cnt-g2) Mus musculus (Mouse) activation of GTPase activity [GO:0090630]; protein transport [GO:0015031] GO:0003924; GO:0005096; GO:0005525; GO:0005543; GO:0005829; GO:0015031; GO:0046872; GO:0090630 30052 XM_029336581.2 1616 1059 798 1337 1177 Q8BXK8 2.36e-36 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 (AGAP-1) (Centaurin-gamma-2) (Cnt-g2) Mus musculus (Mouse) activation of GTPase activity [GO:0090630]; protein transport [GO:0015031] GO:0003924; GO:0005096; GO:0005525; GO:0005543; GO:0005829; GO:0015031; GO:0046872; GO:0090630 30053 XM_044327750.1 360 193 86 76 184 Q05609 5.1e-26 Serine/threonine-protein kinase CTR1 (EC 2.7.11.1) (Protein CONSTITUTIVE TRIPLE RESPONSE1) Arabidopsis thaliana (Mouse-ear cress) ethylene-activated signaling pathway [GO:0009873]; gibberellin biosynthetic process [GO:0009686]; negative regulation of ethylene-activated signaling pathway [GO:0010105]; protein autophosphorylation [GO:0046777]; regulation of post-embryonic root development [GO:2000069]; regulation of stem cell division [GO:2000035]; regulation of timing of transition from vegetative to reproductive phase [GO:0048510]; response to ethylene [GO:0009723]; response to fructose [GO:0009750]; response to hypoxia [GO:0001666]; response to sucrose [GO:0009744]; sugar mediated signaling pathway [GO:0010182] GO:0001666; GO:0004674; GO:0004712; GO:0005524; GO:0005789; GO:0009686; GO:0009723; GO:0009744; GO:0009750; GO:0009873; GO:0010105; GO:0010182; GO:0046777; GO:0048510; GO:0106310; GO:2000035; GO:2000069 30054 XM_029331122.2 47 162 83 178 116 Q9UHC6 2.15e-36 Contactin-associated protein-like 2 (Cell recognition molecule Caspr2) Homo sapiens (Human) adult behavior [GO:0030534]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell population proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; clustering of voltage-gated potassium channels [GO:0045163]; learning [GO:0007612]; limbic system development [GO:0021761]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuron recognition [GO:0008038]; positive regulation of gap junction assembly [GO:1903598]; protein localization to juxtaparanode region of axon [GO:0071205]; social behavior [GO:0035176]; striatum development [GO:0021756]; superior temporal gyrus development [GO:0071109]; thalamus development [GO:0021794]; transmission of nerve impulse [GO:0019226]; vocal learning [GO:0042297]; vocalization behavior [GO:0071625] GO:0005769; GO:0005794; GO:0007155; GO:0007420; GO:0007612; GO:0008038; GO:0008076; GO:0008283; GO:0009986; GO:0016020; GO:0019226; GO:0019899; GO:0021756; GO:0021761; GO:0021794; GO:0021987; GO:0030424; GO:0030425; GO:0030534; GO:0030673; GO:0031175; GO:0033010; GO:0035176; GO:0042297; GO:0043025; GO:0043204; GO:0044224; GO:0045163; GO:0048812; GO:0071109; GO:0071205; GO:0071625; GO:1903598 30055 XM_029337866.2 0 278 0 51 0 Q8BMK0 8.67e-36 Centrosomal protein of 85 kDa (Cep85) (Coiled-coil domain-containing protein 21) Mus musculus (Mouse) chromosome segregation [GO:0007059]; negative regulation of protein kinase activity [GO:0006469]; neuron migration [GO:0001764]; regulation of mitotic centrosome separation [GO:0046602] GO:0000242; GO:0000922; GO:0001764; GO:0005730; GO:0005794; GO:0005813; GO:0005829; GO:0006469; GO:0007059; GO:0046602 30056 XM_044322687.1 325 234 224 390 397 D8VNS8 6.97e-61 Ryncolin-2 Cerberus rynchops (Dog-faced water snake) NA GO:0005576; GO:0090729 30057 XM_044322687.1 325 234 224 390 397 D8VNS8 1.87e-58 Ryncolin-2 Cerberus rynchops (Dog-faced water snake) NA GO:0005576; GO:0090729 30058 XM_044322687.1 325 234 224 390 397 D8VNS8 7.81e-57 Ryncolin-2 Cerberus rynchops (Dog-faced water snake) NA GO:0005576; GO:0090729 30059 XM_029344831.2 1077 2567 725 568 517 Q8N5L8 4.78e-24 Ribonuclease P protein subunit p25-like protein (RNase P protein subunit-like p25) (Rpp25-like protein) Homo sapiens (Human) tRNA 5'-leader removal [GO:0001682] GO:0000172; GO:0001682; GO:0003723; GO:0005634 30060 XM_044318549.1 288 416 283 351 667 Q15527 2.91e-28 Surfeit locus protein 2 (Surf-2) Homo sapiens (Human) NA GO:0005654; GO:0005730; GO:0005886; GO:0016607 30061 XM_029345011.2 674 822 292 849 904 NA NA NA NA NA NA 30062 XM_029328769.2 1078 711 498 722 317 Q28615 3.3e-151 Solute carrier family 13 member 2 (Na(+)/dicarboxylate cotransporter 1) (NaDC-1) (Renal sodium/dicarboxylate cotransporter) Oryctolagus cuniculus (Rabbit) alpha-ketoglutarate transport [GO:0015742]; fumarate transport [GO:0015741]; succinate transmembrane transport [GO:0071422] GO:0015138; GO:0015139; GO:0015141; GO:0015741; GO:0015742; GO:0016324; GO:0017153; GO:0071422 30063 XM_029353956.2 0 155 144 767 752 Q9K7A0 1.38e-29 Probable cysteine desulfurase (EC 2.8.1.7) Halalkalibacterium halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) (Bacillus halodurans) cysteine metabolic process [GO:0006534] GO:0006534; GO:0030170; GO:0031071 30064 XM_029337850.2 4022 2279 2447 4643 2823 P31029 1.47e-144 Alanine--glyoxylate aminotransferase (AGT) (EC 2.6.1.44) (Serine--pyruvate aminotransferase, mitochondrial) (SPT) (EC 2.6.1.51) Callithrix jacchus (White-tufted-ear marmoset) glyoxylate metabolic process [GO:0046487] GO:0004760; GO:0005759; GO:0005777; GO:0008453; GO:0042803; GO:0043621; GO:0046487 30065 XR_003826044.2 13381 10114 9775 7905 5702 NA NA NA NA NA NA 30066 XR_006392195.1 1 0 0 12 6 NA NA NA NA NA NA 30067 XM_029327170.2 818 613 214 456 724 NA NA NA NA NA NA 30068 XM_044327655.1 8 7 0 12 0 NA NA NA NA NA NA 30069 XM_044320152.1 6 9 61 21 0 P70531 9.87e-129 Eukaryotic elongation factor 2 kinase (eEF-2 kinase) (eEF-2K) (EC 2.7.11.20) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase) Rattus norvegicus (Rat) cellular response to anoxia [GO:0071454]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to insulin stimulus [GO:0032869]; negative regulation of apoptotic process [GO:0043066]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of endocytosis [GO:0045807]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; regulation of protein autophosphorylation [GO:0031952]; regulation of translation at postsynapse [GO:0140245]; response to ischemia [GO:0002931]; response to prolactin [GO:1990637] GO:0002931; GO:0004674; GO:0004686; GO:0005509; GO:0005516; GO:0005524; GO:0014069; GO:0031952; GO:0032869; GO:0043066; GO:0043197; GO:0045182; GO:0045807; GO:0046777; GO:0051965; GO:0061003; GO:0071277; GO:0071320; GO:0071454; GO:0098978; GO:0140245; GO:1990416; GO:1990637 30070 XM_044320152.1 6 9 61 21 0 P70531 1.13e-42 Eukaryotic elongation factor 2 kinase (eEF-2 kinase) (eEF-2K) (EC 2.7.11.20) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase) Rattus norvegicus (Rat) cellular response to anoxia [GO:0071454]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to insulin stimulus [GO:0032869]; negative regulation of apoptotic process [GO:0043066]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of endocytosis [GO:0045807]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; regulation of protein autophosphorylation [GO:0031952]; regulation of translation at postsynapse [GO:0140245]; response to ischemia [GO:0002931]; response to prolactin [GO:1990637] GO:0002931; GO:0004674; GO:0004686; GO:0005509; GO:0005516; GO:0005524; GO:0014069; GO:0031952; GO:0032869; GO:0043066; GO:0043197; GO:0045182; GO:0045807; GO:0046777; GO:0051965; GO:0061003; GO:0071277; GO:0071320; GO:0071454; GO:0098978; GO:0140245; GO:1990416; GO:1990637 30071 XM_044306821.1 518 228 377 532 425 Q6P4S8 0 Integrator complex subunit 1 (Int1) Mus musculus (Mouse) blastocyst growth [GO:0001832]; inner cell mass cell proliferation [GO:0001833]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; snRNA processing [GO:0016180]; U2 snRNA 3'-end processing [GO:0034474] GO:0001832; GO:0001833; GO:0005634; GO:0016180; GO:0031965; GO:0032039; GO:0034474; GO:0043066; GO:0043154 30072 XM_029351659.2 876 839 554 666 651 Q7T312 4.89e-76 Coiled-coil domain-containing protein 25 Danio rerio (Zebrafish) (Brachydanio rerio) positive regulation of cell motility [GO:2000147] GO:0003677; GO:0005886; GO:0012505; GO:2000147 30073 XM_044329351.1 0 6 0 11 0 Q3B7D2 1.69e-178 Serine palmitoyltransferase 2 (EC 2.3.1.50) (Long chain base biosynthesis protein 2) (LCB 2) (Serine-palmitoyl-CoA transferase 2) (SPT 2) Rattus norvegicus (Rat) adipose tissue development [GO:0060612]; ceramide biosynthetic process [GO:0046513]; positive regulation of lipophagy [GO:1904504]; sphinganine biosynthetic process [GO:0046511]; sphingolipid biosynthetic process [GO:0030148]; sphingomyelin biosynthetic process [GO:0006686]; sphingosine biosynthetic process [GO:0046512] GO:0004758; GO:0005789; GO:0006686; GO:0017059; GO:0030148; GO:0030170; GO:0046511; GO:0046512; GO:0046513; GO:0060612; GO:1904504 30074 XM_029346146.2 271 168 149 194 367 Q9BWU0 2.44e-95 Kanadaptin (Human lung cancer oncogene 3 protein) (HLC-3) (Kidney anion exchanger adapter protein) (Solute carrier family 4 anion exchanger member 1 adapter protein) Homo sapiens (Human) NA GO:0003729; GO:0005654; GO:0005737; GO:0005886; GO:0043231 30075 XM_029337622.2 0 0 8 23 13 NA NA NA NA NA NA 30076 XM_029337050.2 48 0 0 0 0 NA NA NA NA NA NA 30077 XM_029341325.2 113 50 23 30 65 NA NA NA NA NA NA 30078 XM_029326804.2 73 0 0 807 947 NA NA NA NA NA NA 30079 XM_029333241.2 7877 11815 9969 10456 5212 P52657 1.11e-56 Transcription initiation factor IIA subunit 2 (General transcription factor IIA subunit 2) (TFIIA p12 subunit) (TFIIA-12) (TFIIAS) (Transcription initiation factor IIA gamma chain) (TFIIA-gamma) Homo sapiens (Human) positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription by RNA polymerase II [GO:0006366]; transcription initiation at RNA polymerase II promoter [GO:0006367] GO:0001091; GO:0005634; GO:0005654; GO:0005669; GO:0005672; GO:0006366; GO:0006367; GO:0016251; GO:0017025; GO:0030054; GO:0042803; GO:0045944; GO:0046982; GO:0051123; GO:0060261; GO:0061629 30080 XM_029337102.2 31 40 45 0 0 Q8TCT0 4.36e-75 Ceramide kinase (hCERK) (EC 2.7.1.138) (Acylsphingosine kinase) (Lipid kinase 4) (LK4) Homo sapiens (Human) ceramide metabolic process [GO:0006672]; glycosphingolipid metabolic process [GO:0006687]; phosphorylation [GO:0016310]; sphingolipid metabolic process [GO:0006665] GO:0000287; GO:0001727; GO:0001729; GO:0005524; GO:0005737; GO:0005886; GO:0006665; GO:0006672; GO:0006687; GO:0016020; GO:0016310; GO:0102773 30081 XM_044310495.1 65 203 165 0 0 NA NA NA NA NA NA 30082 XM_044328919.1 33 23 6 4 17 Q2LE78 5.74e-75 BTB/POZ domain-containing protein 6 Xenopus laevis (African clawed frog) NA GO:0005737 30083 XM_029340996.2 17 13 0 4 46 NA NA NA NA NA NA 30084 XM_044310121.1 317 381 275 230 308 NA NA NA NA NA NA 30085 XR_006397928.1 613 869 510 936 679 Q7SZN0 8.19e-22 Venom prothrombin activator pseutarin-C non-catalytic subunit (PCNS) (vPA) (Venom coagulation factor Va-like protein) [Cleaved into: Pseutarin-C non-catalytic subunit heavy chain; Pseutarin-C non-catalytic subunit light chain] Pseudonaja textilis (Eastern brown snake) envenomation resulting in positive regulation of blood coagulation in another organism [GO:0044469]; positive regulation of blood coagulation in another organism [GO:0035807]; positive regulation of peptidase activity [GO:0010952] GO:0005507; GO:0005576; GO:0010952; GO:0016504; GO:0032991; GO:0035807; GO:0044469; GO:0090729 30086 XR_006397928.1 613 869 510 936 679 Q7SZN0 8.19e-22 Venom prothrombin activator pseutarin-C non-catalytic subunit (PCNS) (vPA) (Venom coagulation factor Va-like protein) [Cleaved into: Pseutarin-C non-catalytic subunit heavy chain; Pseutarin-C non-catalytic subunit light chain] Pseudonaja textilis (Eastern brown snake) envenomation resulting in positive regulation of blood coagulation in another organism [GO:0044469]; positive regulation of blood coagulation in another organism [GO:0035807]; positive regulation of peptidase activity [GO:0010952] GO:0005507; GO:0005576; GO:0010952; GO:0016504; GO:0032991; GO:0035807; GO:0044469; GO:0090729 30087 XM_029330680.2 6248 4333 3099 5123 4201 P13498 3.64e-43 Cytochrome b-245 light chain (Cytochrome b(558) alpha chain) (Cytochrome b558 subunit alpha) (Neutrophil cytochrome b 22 kDa polypeptide) (Superoxide-generating NADPH oxidase light chain subunit) (p22 phagocyte B-cytochrome) (p22-phox) (p22phox) Homo sapiens (Human) cellular response to angiotensin [GO:1904385]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose stimulus [GO:0071333]; cellular response to L-glutamine [GO:1904845]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to tumor necrosis factor [GO:0071356]; cytochrome complex assembly [GO:0017004]; establishment of localization in cell [GO:0051649]; hydrogen peroxide biosynthetic process [GO:0050665]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; mucus secretion [GO:0070254]; negative regulation of glomerular filtration by angiotensin [GO:0003106]; positive regulation of cell growth [GO:0030307]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of mucus secretion [GO:0070257]; positive regulation of NAD(P)H oxidase activity [GO:0033864]; positive regulation of phagocytosis [GO:0050766]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of toll-like receptor 2 signaling pathway [GO:0034137]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; respiratory burst [GO:0045730]; response to activity [GO:0014823]; response to aldosterone [GO:1904044]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to nutrient levels [GO:0031667]; response to xenobiotic stimulus [GO:0009410]; smooth muscle hypertrophy [GO:0014895]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801] GO:0001666; GO:0001725; GO:0001938; GO:0003106; GO:0005634; GO:0005768; GO:0005789; GO:0005794; GO:0005886; GO:0005925; GO:0006801; GO:0006954; GO:0009055; GO:0009410; GO:0014823; GO:0014895; GO:0016020; GO:0016175; GO:0016324; GO:0017004; GO:0017124; GO:0020037; GO:0030141; GO:0030307; GO:0030425; GO:0030670; GO:0031667; GO:0032755; GO:0032760; GO:0032930; GO:0033864; GO:0034137; GO:0035579; GO:0042554; GO:0043020; GO:0043025; GO:0045087; GO:0045730; GO:0046872; GO:0046982; GO:0048661; GO:0050665; GO:0050766; GO:0051279; GO:0051649; GO:0070254; GO:0070257; GO:0070555; GO:0070821; GO:0071260; GO:0071333; GO:0071356; GO:0071407; GO:0071480; GO:0097038; GO:1900426; GO:1903428; GO:1904044; GO:1904385; GO:1904845 30088 XM_044317576.1 27 25 12 6 21 NA NA NA NA NA NA 30089 XM_029335361.2 0 86 31 144 0 P30884 3.84e-76 Bone morphogenetic protein 2-B (BMP-2-II) Xenopus laevis (African clawed frog) cartilage development [GO:0051216]; cell differentiation [GO:0030154]; ossification [GO:0001503] GO:0001503; GO:0005125; GO:0005615; GO:0008083; GO:0030154; GO:0051216 30090 XM_029355318.2 19 0 0 0 60 NA NA NA NA NA NA 30091 XM_044319456.1 0 1 0 0 9 NA NA NA NA NA NA 30092 XM_029324631.2 18 0 17 25 48 Q9D411 2.62e-78 Testis-specific serine/threonine-protein kinase 4 (TSK-4) (TSSK-4) (Testis-specific kinase 4) (EC 2.7.11.1) Mus musculus (Mouse) fertilization [GO:0009566]; flagellated sperm motility [GO:0030317]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine autophosphorylation [GO:1990443]; positive regulation of CREB transcription factor activity [GO:0032793]; protein phosphorylation [GO:0006468]; spermatid development [GO:0007286] GO:0000287; GO:0001669; GO:0004672; GO:0004674; GO:0005524; GO:0006468; GO:0007286; GO:0009566; GO:0018105; GO:0030317; GO:0031514; GO:0032793; GO:0035556; GO:0036126; GO:0042802; GO:0042803; GO:0044877; GO:0106310; GO:1990443 30093 XR_006398052.1 0 0 0 24 48 NA NA NA NA NA NA 30094 XM_044316294.1 0 51 0 48 18 NA NA NA NA NA NA 30095 XM_029336269.2 0 0 0 0 9 NA NA NA NA NA NA 30096 XM_044327839.1 375 508 280 337 211 NA NA NA NA NA NA 30097 XM_044311903.1 125 46 81 57 339 Q09575 2.46e-50 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 30098 XM_029336977.2 164 136 14 179 118 Q8K4Z4 5.71e-32 Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor) Cavia porcellus (Guinea pig) activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; bone resorption [GO:0045453]; brown fat cell differentiation [GO:0050873]; cellular response to amyloid-beta [GO:1904646]; desensitization of G protein-coupled receptor signaling pathway by arrestin [GO:0002032]; diet induced thermogenesis [GO:0002024]; heat generation [GO:0031649]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of smooth muscle contraction [GO:0045986]; norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0002025]; positive regulation of AMPA receptor activity [GO:2000969]; positive regulation of autophagosome maturation [GO:1901098]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of lipophagy [GO:1904504]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mini excitatory postsynaptic potential [GO:0061885]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor-mediated endocytosis [GO:0006898]; regulation of sodium ion transport [GO:0002028]; response to cold [GO:0009409]; smooth muscle contraction [GO:0006939]; transcription by RNA polymerase II [GO:0006366] GO:0001540; GO:0002024; GO:0002025; GO:0002028; GO:0002032; GO:0004941; GO:0005634; GO:0005769; GO:0005794; GO:0006366; GO:0006898; GO:0006939; GO:0007189; GO:0007190; GO:0008179; GO:0009409; GO:0010739; GO:0015459; GO:0016324; GO:0030501; GO:0031649; GO:0040015; GO:0042803; GO:0043235; GO:0043410; GO:0044877; GO:0045453; GO:0045944; GO:0045986; GO:0050873; GO:0051380; GO:0061885; GO:0071902; GO:0098992; GO:0120162; GO:1901098; GO:1904504; GO:1904646; GO:2000969 30099 XR_006397150.1 358 182 343 3001 1107 NA NA NA NA NA NA 30100 XR_006398055.1 0 50 36 34 60 NA NA NA NA NA NA 30101 XM_029354010.2 684 696 531 790 773 Q99LM2 1.09e-137 CDK5 regulatory subunit-associated protein 3 Mus musculus (Mouse) apoptotic nuclear changes [GO:0030262]; cell population proliferation [GO:0008283]; definitive erythrocyte differentiation [GO:0060318]; endoplasmic reticulum unfolded protein response [GO:0030968]; liver development [GO:0001889]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; mitotic G2/M transition checkpoint [GO:0044818]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of signal transduction by p53 class mediator [GO:1901798]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein ufmylation [GO:0071569]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of mitotic cell cycle [GO:0007346]; regulation of phosphatase activity [GO:0010921]; response to endoplasmic reticulum stress [GO:0034976] GO:0000079; GO:0001889; GO:0001933; GO:0005634; GO:0005730; GO:0005737; GO:0005813; GO:0005829; GO:0005874; GO:0007095; GO:0007346; GO:0008283; GO:0010921; GO:0019901; GO:0030262; GO:0030332; GO:0030968; GO:0031398; GO:0032088; GO:0032991; GO:0034976; GO:0042177; GO:0043231; GO:0043407; GO:0044387; GO:0044389; GO:0044818; GO:0044877; GO:0045736; GO:0045944; GO:0051019; GO:0051059; GO:0060318; GO:0071569; GO:0071901; GO:0097371; GO:1900182; GO:1901798 30102 XM_044314087.1 8 0 30 3 43 NA NA NA NA NA NA 30103 XM_029356571.2 629 477 415 614 736 Q642H7 2.22e-50 Synembryn-A (Protein Ric-8A) Danio rerio (Zebrafish) (Brachydanio rerio) G protein-coupled receptor signaling pathway [GO:0007186] GO:0001965; GO:0005085; GO:0005737; GO:0005886; GO:0007186 30104 XM_029355359.2 453 0 138 310 1 NA NA NA NA NA NA 30105 XR_006391410.1 160 70 54 59 133 NA NA NA NA NA NA 30106 XR_003828441.2 15 13 1 44 89 NA NA NA NA NA NA 30107 XM_029344119.2 251 120 69 194 253 Q5RA17 5.18e-44 Ribosomal RNA-processing protein 7 homolog A (Gastric cancer antigen Zg14 homolog) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cilium disassembly [GO:0061523]; ribosome biogenesis [GO:0042254]; rRNA processing [GO:0006364] GO:0003723; GO:0005730; GO:0005737; GO:0005813; GO:0005929; GO:0006364; GO:0042254; GO:0061523 30108 XR_006392086.1 393 186 184 353 591 NA NA NA NA NA NA 30109 XM_044313526.1 44 0 3 129 146 A0A0C2SRU0 3.75e-79 Decarboxylase iboD (EC 4.1.1.-) (Ibotenic acid biosynthesis cluster protein D) Amanita muscaria (strain Koide BX008) phospholipid biosynthetic process [GO:0008654] GO:0004609; GO:0008654 30110 XR_006392470.1 560 672 503 828 556 Q6VAB6 2.7e-47 Kinase suppressor of Ras 2 (hKSR2) (EC 2.7.11.1) Homo sapiens (Human) calcium-mediated signaling [GO:0019722]; positive regulation of cold-induced thermogenesis [GO:0120162]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; signal transduction [GO:0007165] GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006468; GO:0007165; GO:0007265; GO:0019722; GO:0046872; GO:0106310; GO:0120162 30111 XM_044326894.1 65 0 102 0 0 NA NA NA NA NA NA 30112 XR_006394431.1 727 472 293 91 175 NA NA NA NA NA NA 30113 XM_029357617.2 10 0 0 0 0 Q8CGS5 3.15e-112 Zinc phosphodiesterase ELAC protein 2 (EC 3.1.26.11) (ElaC homolog protein 2) (Ribonuclease Z 2) (RNase Z 2) (tRNA 3 endonuclease 2) (tRNase Z 2) Rattus norvegicus (Rat) mitochondrial tRNA 3'-trailer cleavage, endonucleolytic [GO:0072684] GO:0004549; GO:0005634; GO:0005739; GO:0042645; GO:0042781; GO:0046872; GO:0072684 30114 XR_006396603.1 20 6 25 36 93 NA NA NA NA NA NA 30115 XM_029329275.2 18311 13601 9529 13636 14176 Q9F234 1.11e-88 Alpha-glucosidase 2 (EC 3.2.1.20) (Alpha-glucosidase II) Bacillus thermoamyloliquefaciens NA GO:0030246; GO:0032450 30116 XR_003825975.2 17375 2880 2297 538 2241 NA NA NA NA NA NA 30117 XM_029332898.2 0 187 0 1 1 NA NA NA NA NA NA 30118 XM_029336327.2 117 200 246 59 263 NA NA NA NA NA NA 30119 XR_006391812.1 3 0 4 2 7 NA NA NA NA NA NA 30120 XR_003827193.1 10 0 4 0 3 NA NA NA NA NA NA 30121 XM_029351628.2 24 9 17 7 90 Q9UHC6 7.19e-29 Contactin-associated protein-like 2 (Cell recognition molecule Caspr2) Homo sapiens (Human) adult behavior [GO:0030534]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell population proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; clustering of voltage-gated potassium channels [GO:0045163]; learning [GO:0007612]; limbic system development [GO:0021761]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuron recognition [GO:0008038]; positive regulation of gap junction assembly [GO:1903598]; protein localization to juxtaparanode region of axon [GO:0071205]; social behavior [GO:0035176]; striatum development [GO:0021756]; superior temporal gyrus development [GO:0071109]; thalamus development [GO:0021794]; transmission of nerve impulse [GO:0019226]; vocal learning [GO:0042297]; vocalization behavior [GO:0071625] GO:0005769; GO:0005794; GO:0007155; GO:0007420; GO:0007612; GO:0008038; GO:0008076; GO:0008283; GO:0009986; GO:0016020; GO:0019226; GO:0019899; GO:0021756; GO:0021761; GO:0021794; GO:0021987; GO:0030424; GO:0030425; GO:0030534; GO:0030673; GO:0031175; GO:0033010; GO:0035176; GO:0042297; GO:0043025; GO:0043204; GO:0044224; GO:0045163; GO:0048812; GO:0071109; GO:0071205; GO:0071625; GO:1903598 30122 XM_044327111.1 5 5 1 1 98 NA NA NA NA NA NA 30123 XM_044325814.1 19 34 5 32 63 NA NA NA NA NA NA 30124 XM_044322393.1 13 0 58 0 83 NA NA NA NA NA NA 30125 XM_029336903.2 573 422 346 524 293 Q8HYJ5 3.46e-43 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3 (EC 2.4.1.65) (4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase) (EC 2.4.1.152) (Alpha-3-fucosyltransferase FUT3) (EC 2.4.1.-) (Alpha-3/4-fucosyltransferase) (Blood group Lewis alpha-4-fucosyltransferase) (Lewis FT) (Fucosyltransferase 3) (Fucosyltransferase III) (FucT-III) Pongo pygmaeus (Bornean orangutan) fucosylation [GO:0036065]; lipid metabolic process [GO:0006629]; oligosaccharide metabolic process [GO:0009311]; positive regulation of cell-cell adhesion [GO:0022409]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127] GO:0006487; GO:0006493; GO:0006629; GO:0009311; GO:0017060; GO:0017083; GO:0022409; GO:0030334; GO:0032580; GO:0036065; GO:0042127 30126 XM_029356227.2 352 346 207 486 274 Q9JIM4 2.6e-65 Dual specificity protein phosphatase 12 (EC 3.1.3.16) (EC 3.1.3.48) (Glucokinase-associated dual specificity phosphatase) (GKAP) Rattus norvegicus (Rat) dephosphorylation [GO:0016311]; positive regulation of glucokinase activity [GO:0033133]; protein dephosphorylation [GO:0006470] GO:0004721; GO:0004725; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006470; GO:0008138; GO:0008270; GO:0016311; GO:0016791; GO:0017018; GO:0019900; GO:0033133 30127 XM_029323880.2 1208 602 764 1058 1098 Q9EPW0 3.3e-176 Inositol polyphosphate-4-phosphatase type I A (Inositol polyphosphate 4-phosphatase type I) (Inositol polyphosphate 4-phosphatase-1) (4-Ptase-1) (Type I inositol 3,4-bisphosphate 4-phosphatase) (EC 3.1.3.66) Mus musculus (Mouse) polyphosphate catabolic process [GO:0006798] GO:0005634; GO:0005654; GO:0005737; GO:0005886; GO:0006798; GO:0014069; GO:0016316; GO:0017161; GO:0031901; GO:0031965; GO:0052828; GO:0055038 30128 XM_044308646.1 22894 11282 5953 41425 45807 Q90243 2.41e-55 Vitellogenin (VTG) [Cleaved into: Lipovitellin I (LVI); Phosvitin (PV); Lipovitellin II (LVII)] Acipenser transmontanus (White sturgeon) NA GO:0005319; GO:0045735 30129 XR_006396553.1 51 19 29 18 0 NA NA NA NA NA NA 30130 XM_044327727.1 316 163 23 97 93 NA NA NA NA NA NA 30131 XM_044327506.1 8 0 8 15 47 NA NA NA NA NA NA 30132 XM_044310032.1 422 0 96 23 26 P70490 3.17e-52 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 30133 XM_044310032.1 422 0 96 23 26 P70490 4.38e-52 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 30134 XM_044310032.1 422 0 96 23 26 P70490 4.87e-52 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 30135 XM_044310032.1 422 0 96 23 26 P70490 3.93e-51 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 30136 XM_044310032.1 422 0 96 23 26 P70490 4.37e-51 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 30137 XM_044310032.1 422 0 96 23 26 P70490 1.04e-50 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 30138 XM_044310032.1 422 0 96 23 26 P70490 1.23e-50 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 30139 XM_044310032.1 422 0 96 23 26 P70490 3e-50 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 30140 XM_044310032.1 422 0 96 23 26 P70490 6.73e-50 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 30141 XM_044310032.1 422 0 96 23 26 P70490 1.02e-49 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 30142 XM_044310032.1 422 0 96 23 26 P70490 1.64e-49 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 30143 XM_044310032.1 422 0 96 23 26 P70490 2.1e-49 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 30144 XM_044310032.1 422 0 96 23 26 P70490 3.13e-49 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 30145 XM_044310032.1 422 0 96 23 26 P70490 7.7e-49 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 30146 XM_044310032.1 422 0 96 23 26 P70490 9.14e-49 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 30147 XM_044310032.1 422 0 96 23 26 P70490 1.41e-48 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 30148 XM_044310032.1 422 0 96 23 26 P70490 4.41e-48 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 30149 XM_044310032.1 422 0 96 23 26 P70490 1.27e-46 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 30150 XM_044310032.1 422 0 96 23 26 P70490 1.26e-35 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 30151 XM_044310032.1 422 0 96 23 26 P70490 1.26e-35 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 30152 XM_029324281.2 0 0 8 2 0 NA NA NA NA NA NA 30153 XM_044308289.1 237 95 108 26 132 NA NA NA NA NA NA 30154 XM_044320557.1 98 59 47 19 179 B8V7S0 0 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 30155 XM_044320557.1 98 59 47 19 179 B8V7S0 5.71e-124 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 30156 XM_044320557.1 98 59 47 19 179 B8V7S0 3.34e-37 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 30157 XM_044320557.1 98 59 47 19 179 B8V7S0 3.93e-28 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 30158 XM_029338993.2 794 617 562 587 316 P80311 9.69e-94 Peptidyl-prolyl cis-trans isomerase B (PPIase B) (EC 5.2.1.8) (Cyclophilin B) (Rotamase B) (S-cyclophilin) (SCYLP) Bos taurus (Bovine) bone development [GO:0060348]; chaperone-mediated protein folding [GO:0061077]; neutrophil chemotaxis [GO:0030593]; positive regulation by host of viral genome replication [GO:0044829]; positive regulation of multicellular organism growth [GO:0040018]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821] GO:0000413; GO:0003755; GO:0005654; GO:0005737; GO:0005788; GO:0006457; GO:0016018; GO:0030593; GO:0032991; GO:0034663; GO:0040018; GO:0042470; GO:0043231; GO:0044829; GO:0048471; GO:0050821; GO:0060348; GO:0061077; GO:0070063 30159 XM_029346579.2 609 401 263 478 483 NA NA NA NA NA NA 30160 XR_006396955.1 0 0 1 7 7 NA NA NA NA NA NA 30161 XM_044315541.1 0 0 42 0 0 NA NA NA NA NA NA 30162 XM_044312421.1 4 1 3 3 53 NA NA NA NA NA NA 30163 XM_029329035.2 13 21 22 13 0 P17971 8.38e-122 Potassium voltage-gated channel protein Shal (Shaker cognate l) (Shal2) Drosophila melanogaster (Fruit fly) associative learning [GO:0008306]; chemical synaptic transmission [GO:0007268]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005250; GO:0005886; GO:0006813; GO:0007268; GO:0008076; GO:0008306; GO:0016020; GO:0030425; GO:0034765; GO:0043204; GO:0045202; GO:0051260; GO:0071805 30164 XR_006395411.1 1 14 0 0 0 NA NA NA NA NA NA 30165 XM_029336546.2 312 185 193 378 306 Q6GNV7 5.83e-88 Solute carrier family 49 member 4 homolog (Disrupted in renal carcinoma protein 2 homolog) Xenopus laevis (African clawed frog) NA GO:0005765; GO:0022857 30166 XM_044308262.1 220 634 93 420 287 NA NA NA NA NA NA 30167 XM_044315166.1 2 1 0 4 16 NA NA NA NA NA NA 30168 XM_029328609.2 37 22 20 25 90 Q9H2X9 0 Solute carrier family 12 member 5 (Electroneutral potassium-chloride cotransporter 2) (K-Cl cotransporter 2) (hKCC2) (Neuronal K-Cl cotransporter) Homo sapiens (Human) cell volume homeostasis [GO:0006884]; cellular chloride ion homeostasis [GO:0030644]; cellular ion homeostasis [GO:0006873]; chemical synaptic transmission [GO:0007268]; chloride ion homeostasis [GO:0055064]; chloride transmembrane transport [GO:1902476]; dendritic spine development [GO:0060996]; hypotonic response [GO:0006971]; intracellular pH reduction [GO:0051452]; ion transport [GO:0006811]; learning [GO:0007612]; multicellular organism growth [GO:0035264]; potassium ion homeostasis [GO:0055075]; potassium ion import across plasma membrane [GO:1990573]; response to xenobiotic stimulus [GO:0009410]; thermosensory behavior [GO:0040040] GO:0005886; GO:0006811; GO:0006873; GO:0006884; GO:0006971; GO:0007268; GO:0007612; GO:0008519; GO:0009410; GO:0015108; GO:0015379; GO:0016020; GO:0019901; GO:0030644; GO:0032590; GO:0035264; GO:0040040; GO:0043005; GO:0043025; GO:0043204; GO:0045202; GO:0051452; GO:0055064; GO:0055075; GO:0060996; GO:0071944; GO:1902476; GO:1990573 30169 XM_029349916.2 734 404 325 358 304 Q9H237 1.86e-100 Protein-serine O-palmitoleoyltransferase porcupine (EC 2.3.1.250) (Protein MG61) Homo sapiens (Human) glycoprotein metabolic process [GO:0009100]; lipid modification [GO:0030258]; protein lipidation [GO:0006497]; protein palmitoleylation [GO:0045234]; protein palmitoylation [GO:0018345]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; Wnt protein secretion [GO:0061355]; Wnt signaling pathway [GO:0016055] GO:0005783; GO:0005789; GO:0006497; GO:0009100; GO:0016020; GO:0016055; GO:0016746; GO:0017147; GO:0018345; GO:0030258; GO:0032281; GO:0045234; GO:0061355; GO:0098978; GO:0099072; GO:1990698 30170 XR_006391882.1 0 0 14 2 0 P97321 7.87e-72 Prolyl endopeptidase FAP (EC 3.4.21.26) (Dipeptidyl peptidase FAP) (EC 3.4.14.5) (Fibroblast activation protein alpha) (FAPalpha) (Gelatine degradation protease FAP) (EC 3.4.21.-) (Integral membrane serine protease) (Post-proline cleaving enzyme) (Serine integral membrane protease) (SIMP) (Surface-expressed protease) (Seprase) [Cleaved into: Antiplasmin-cleaving enzyme FAP, soluble form (APCE) (EC 3.4.14.5) (EC 3.4.21.-) (EC 3.4.21.26)] Mus musculus (Mouse) angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; melanocyte apoptotic process [GO:1902362]; melanocyte proliferation [GO:0097325]; negative regulation of cell proliferation involved in contact inhibition [GO:0060244]; negative regulation of extracellular matrix disassembly [GO:0010716]; negative regulation of extracellular matrix organization [GO:1903054]; positive regulation of execution phase of apoptosis [GO:1900119]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of cell cycle [GO:0051726]; regulation of collagen catabolic process [GO:0010710] GO:0001525; GO:0002020; GO:0004175; GO:0004252; GO:0005178; GO:0005615; GO:0005886; GO:0006508; GO:0007155; GO:0008233; GO:0008236; GO:0008239; GO:0009986; GO:0010710; GO:0010716; GO:0030027; GO:0031258; GO:0032587; GO:0042802; GO:0042803; GO:0043542; GO:0045177; GO:0045178; GO:0051603; GO:0051726; GO:0060244; GO:0070161; GO:0097325; GO:1900119; GO:1902362; GO:1903054; GO:1905368 30171 XM_044312189.1 6 0 3 2 31 NA NA NA NA NA NA 30172 XM_044327148.1 7398 7908 6304 10270 10805 B8VIW9 0 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 30173 XM_029346126.2 124 32 58 27 101 NA NA NA NA NA NA 30174 XM_044314944.1 201 181 312 3 1 NA NA NA NA NA NA 30175 XM_044329064.1 387 759 498 796 579 NA NA NA NA NA NA 30176 XM_044308844.1 0 0 0 135 0 O16025 1.73e-46 Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (AOS) (EC 4.2.1.-) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)] Plexaura homomalla (Black sea rod) arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; lipid oxidation [GO:0034440]; oxylipin biosynthetic process [GO:0031408] GO:0005506; GO:0005737; GO:0006633; GO:0009978; GO:0016020; GO:0019369; GO:0020037; GO:0031408; GO:0034440; GO:0047677 30177 XM_029354357.2 9443 10696 1754 8156 5281 O97125 0 Heat shock protein 68 Drosophila melanogaster (Fruit fly) cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; determination of adult lifespan [GO:0008340]; protein refolding [GO:0042026]; response to starvation [GO:0042594]; vesicle-mediated transport [GO:0016192] GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0008340; GO:0016192; GO:0016887; GO:0031072; GO:0034620; GO:0042026; GO:0042594; GO:0044183; GO:0051082; GO:0051085; GO:0051787; GO:0140662 30178 XM_029348759.2 2730 2981 1722 4556 5425 Q9D1L0 3.31e-29 Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 Mus musculus (Mouse) cellular response to oxidative stress [GO:0034599]; mitochondrion organization [GO:0007005]; positive regulation of mitochondrial ATP synthesis coupled electron transport [GO:1905448]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cellular response to hypoxia [GO:1900037] GO:0005634; GO:0005739; GO:0005758; GO:0007005; GO:0034599; GO:0043565; GO:0045944; GO:0140297; GO:1900037; GO:1905448 30179 XM_044316660.1 798 622 386 950 1005 P21956 8.26e-23 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (SED1) (Sperm surface protein SP47) (MP47) Mus musculus (Mouse) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0007155; GO:0007338; GO:0009897; GO:0043277; GO:0062023 30180 XM_029329659.2 1715 910 699 1161 583 Q6NYU7 3.82e-100 Uracil phosphoribosyltransferase homolog Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005525; GO:0005634; GO:0005737; GO:0005829 30181 XM_044306981.1 461 659 579 886 960 P18754 6.39e-114 Regulator of chromosome condensation (Cell cycle regulatory protein) (Chromosome condensation protein 1) Homo sapiens (Human) cell division [GO:0051301]; chromosome segregation [GO:0007059]; G1/S transition of mitotic cell cycle [GO:0000082]; mitotic nuclear membrane reassembly [GO:0007084]; mitotic spindle organization [GO:0007052]; regulation of mitotic nuclear division [GO:0007088]; spindle assembly [GO:0051225]; viral process [GO:0016032] GO:0000082; GO:0000785; GO:0000794; GO:0003682; GO:0005085; GO:0005634; GO:0005654; GO:0005694; GO:0005737; GO:0007052; GO:0007059; GO:0007084; GO:0007088; GO:0016032; GO:0031267; GO:0031491; GO:0031492; GO:0031965; GO:0032991; GO:0042393; GO:0043199; GO:0046982; GO:0051225; GO:0051301 30182 XM_044316237.1 9 0 13 0 46 NA NA NA NA NA NA 30183 XM_029350224.2 199 163 191 634 550 Q9R0Z9 2.23e-161 Rho GTPase-activating protein 7 (Deleted in liver cancer 1 protein homolog) (DLC-1) (Rho-type GTPase-activating protein 7) (START domain-containing protein 12) (StARD12) (StAR-related lipid transfer protein 12) Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of phospholipase C activity [GO:0007202]; apoptotic process [GO:0006915]; cytoskeleton organization [GO:0007010]; focal adhesion assembly [GO:0048041]; forebrain development [GO:0030900]; heart morphogenesis [GO:0003007]; hindbrain morphogenesis [GO:0021575]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of stress fiber assembly [GO:0051497]; neural tube closure [GO:0001843]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; regulation of Rho protein signal transduction [GO:0035023]; signal transduction [GO:0007165] GO:0001725; GO:0001843; GO:0003007; GO:0005096; GO:0005634; GO:0005737; GO:0005829; GO:0005884; GO:0005901; GO:0005925; GO:0006915; GO:0006919; GO:0007010; GO:0007165; GO:0007202; GO:0008285; GO:0008289; GO:0008360; GO:0017166; GO:0021575; GO:0030036; GO:0030336; GO:0030864; GO:0030900; GO:0032587; GO:0032956; GO:0035023; GO:0035024; GO:0035307; GO:0042169; GO:0043274; GO:0045121; GO:0048041; GO:0051497; GO:0051895; GO:1900119 30184 XM_029350224.2 199 163 191 634 550 Q9R0Z9 1.47e-24 Rho GTPase-activating protein 7 (Deleted in liver cancer 1 protein homolog) (DLC-1) (Rho-type GTPase-activating protein 7) (START domain-containing protein 12) (StARD12) (StAR-related lipid transfer protein 12) Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of phospholipase C activity [GO:0007202]; apoptotic process [GO:0006915]; cytoskeleton organization [GO:0007010]; focal adhesion assembly [GO:0048041]; forebrain development [GO:0030900]; heart morphogenesis [GO:0003007]; hindbrain morphogenesis [GO:0021575]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of stress fiber assembly [GO:0051497]; neural tube closure [GO:0001843]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; regulation of Rho protein signal transduction [GO:0035023]; signal transduction [GO:0007165] GO:0001725; GO:0001843; GO:0003007; GO:0005096; GO:0005634; GO:0005737; GO:0005829; GO:0005884; GO:0005901; GO:0005925; GO:0006915; GO:0006919; GO:0007010; GO:0007165; GO:0007202; GO:0008285; GO:0008289; GO:0008360; GO:0017166; GO:0021575; GO:0030036; GO:0030336; GO:0030864; GO:0030900; GO:0032587; GO:0032956; GO:0035023; GO:0035024; GO:0035307; GO:0042169; GO:0043274; GO:0045121; GO:0048041; GO:0051497; GO:0051895; GO:1900119 30185 XM_044327006.1 3 0 0 0 12 NA NA NA NA NA NA 30186 XR_006395426.1 0 1 0 0 6 NA NA NA NA NA NA 30187 XM_029337692.2 35 21 38 4 49 Q5U3Y5 2.88e-46 Vesicle transport protein SFT2A (SFT2 domain-containing protein 1) Rattus norvegicus (Rat) protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] GO:0015031; GO:0016020; GO:0016192 30188 XM_044323170.1 6000 10 19 2418 288 NA NA NA NA NA NA 30189 XM_044317052.1 426 68 209 75 198 Q96D71 1.15e-25 RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1) Homo sapiens (Human) endocytosis [GO:0006897]; endosomal transport [GO:0016197] GO:0005509; GO:0005829; GO:0005886; GO:0005905; GO:0006897; GO:0016197; GO:0017124 30190 XM_029347111.2 21 58 16 26 0 NA NA NA NA NA NA 30191 XM_029349693.2 21 12 6 57 163 P08289 2.45e-148 Alkaline phosphatase, tissue-nonspecific isozyme (AP-TNAP) (TNAP) (TNSALP) (EC 3.1.3.1) (Alkaline phosphatase liver/bone/kidney isozyme) (Phosphoamidase) (Phosphocreatine phosphatase) (EC 3.9.1.1) Rattus norvegicus (Rat) bone mineralization [GO:0030282]; calcium ion homeostasis [GO:0055074]; cellular homeostasis [GO:0019725]; cellular response to organic cyclic compound [GO:0071407]; cementum mineralization [GO:0071529]; dephosphorylation [GO:0016311]; developmental process involved in reproduction [GO:0003006]; endochondral ossification [GO:0001958]; futile creatine cycle [GO:0140651]; multicellular organism aging [GO:0010259]; phosphate ion homeostasis [GO:0055062]; positive regulation of cold-induced thermogenesis [GO:0120162]; pyridoxal phosphate metabolic process [GO:0042822]; response to antibiotic [GO:0046677]; response to glucocorticoid [GO:0051384]; response to insulin [GO:0032868]; response to lipopolysaccharide [GO:0032496]; response to macrophage colony-stimulating factor [GO:0036005]; response to organic cyclic compound [GO:0014070]; response to sodium phosphate [GO:1904383]; response to vitamin B6 [GO:0034516]; response to vitamin D [GO:0033280] GO:0001958; GO:0003006; GO:0004035; GO:0004427; GO:0005509; GO:0005615; GO:0005758; GO:0005886; GO:0010259; GO:0014070; GO:0016311; GO:0016462; GO:0016887; GO:0019725; GO:0030282; GO:0031012; GO:0031966; GO:0032496; GO:0032868; GO:0033280; GO:0033883; GO:0034516; GO:0036005; GO:0042822; GO:0043262; GO:0046677; GO:0050187; GO:0051384; GO:0052732; GO:0055062; GO:0055074; GO:0065010; GO:0071407; GO:0071529; GO:0120162; GO:0140651; GO:1904383 30192 XM_029344043.2 71 0 0 24 11 NA NA NA NA NA NA 30193 XM_029350393.2 892 435 185 455 399 NA NA NA NA NA NA 30194 XR_006393610.1 0 0 0 0 8 NA NA NA NA NA NA 30195 XM_029347799.2 242 90 176 193 281 B8VIU6 4.51e-53 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 30196 XM_029338687.2 273 124 176 243 145 NA NA NA NA NA NA 30197 XM_044324584.1 30 8 12 66 19 NA NA NA NA NA NA 30198 XM_044325573.1 29 22 0 44 61 NA NA NA NA NA NA 30199 XM_044309730.1 0 0 0 1 26 NA NA NA NA NA NA 30200 XM_044316975.1 173 111 121 199 92 NA NA NA NA NA NA 30201 XM_029358161.2 646 502 487 713 959 O43719 6.75e-94 HIV Tat-specific factor 1 (Tat-SF1) Homo sapiens (Human) mRNA splicing, via spliceosome [GO:0000398]; regulation of DNA-templated transcription elongation [GO:0032784]; regulation of transcription by RNA polymerase II [GO:0006357]; U2-type prespliceosome assembly [GO:1903241]; viral genome replication [GO:0019079] GO:0000398; GO:0003723; GO:0005634; GO:0005654; GO:0005681; GO:0005684; GO:0005686; GO:0006357; GO:0019079; GO:0032784; GO:1903241 30202 XM_044324249.1 160 105 106 137 309 NA NA NA NA NA NA 30203 XR_006395020.1 95 207 101 175 224 NA NA NA NA NA NA 30204 XM_029344418.2 1923 1388 1178 2106 1815 A8QMS7 3.32e-36 Myeloid differentiation primary response protein MyD88 Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) inflammatory response [GO:0006954]; innate immune response [GO:0045087]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123] GO:0002755; GO:0005737; GO:0006954; GO:0043123; GO:0045087; GO:0070976 30205 XM_029326414.2 483 310 246 689 694 NA NA NA NA NA NA 30206 XM_044319338.1 33 0 2 49 0 NA NA NA NA NA NA 30207 XM_044327711.1 7 329 2 228 0 NA NA NA NA NA NA 30208 XM_029335363.2 0 0 0 59 0 P30884 3.69e-76 Bone morphogenetic protein 2-B (BMP-2-II) Xenopus laevis (African clawed frog) cartilage development [GO:0051216]; cell differentiation [GO:0030154]; ossification [GO:0001503] GO:0001503; GO:0005125; GO:0005615; GO:0008083; GO:0030154; GO:0051216 30209 XR_006397315.1 80 36 89 133 22 NA NA NA NA NA NA 30210 XM_029340434.2 0 0 0 0 36 Q96QE2 1.44e-174 Proton myo-inositol cotransporter (H(+)-myo-inositol cotransporter) (Hmit) (H(+)-myo-inositol symporter) (Solute carrier family 2 member 13) Homo sapiens (Human) myo-inositol transport [GO:0015798]; positive regulation of amyloid-beta formation [GO:1902004]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104] GO:0002020; GO:0005365; GO:0005366; GO:0005737; GO:0005886; GO:0015798; GO:0016020; GO:0016324; GO:0022857; GO:0030426; GO:0031090; GO:0042995; GO:0043231; GO:0044297; GO:0051117; GO:0055085; GO:0071944; GO:0097450; GO:0150104; GO:1902004 30211 XM_044325875.1 45 32 53 0 57 NA NA NA NA NA NA 30212 XM_029343059.2 0 19 11 0 0 P54833 3.4e-24 Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor) Canis lupus familiaris (Dog) (Canis familiaris) activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; desensitization of G protein-coupled receptor signaling pathway by arrestin [GO:0002032]; negative regulation of smooth muscle contraction [GO:0045986]; norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0002025]; positive regulation of autophagosome maturation [GO:1901098]; positive regulation of lipophagy [GO:1904504]; positive regulation of MAPK cascade [GO:0043410]; receptor-mediated endocytosis [GO:0006898] GO:0002025; GO:0002032; GO:0004930; GO:0004941; GO:0005769; GO:0005794; GO:0005886; GO:0006898; GO:0007190; GO:0042803; GO:0043235; GO:0043410; GO:0045986; GO:0051380; GO:0071880; GO:1901098; GO:1904504 30213 XM_029340214.2 118 46 42 127 80 NA NA NA NA NA NA 30214 XM_044311273.1 135 112 136 79 360 F1R4Y7 1.88e-71 Centrosomal protein of 83 kDa (Cep83) (Coiled-coil domain-containing protein 41) Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; establishment of centrosome localization [GO:0051660] GO:0005737; GO:0005814; GO:0051660; GO:0060271; GO:0097539 30215 XR_006392388.1 10 0 0 0 0 NA NA NA NA NA NA 30216 XM_029335726.2 37 44 60 20 151 NA NA NA NA NA NA 30217 XM_044324709.1 0 0 9 24 1 NA NA NA NA NA NA 30218 XM_044312698.1 65 11 278 246 111 NA NA NA NA NA NA 30219 XM_029340385.2 18 5 4 6 0 NA NA NA NA NA NA 30220 XM_044307326.1 0 0 0 0 14 P53762 1.94e-142 Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1-beta) (HIF-1-beta) (HIF1-beta) Mus musculus (Mouse) cell differentiation [GO:0030154]; embryonic placenta development [GO:0001892]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of hormone biosynthetic process [GO:0046886]; positive regulation of protein sumoylation [GO:0033235]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to hypoxia [GO:0001666]; response to toxic substance [GO:0009636] GO:0000978; GO:0000981; GO:0000987; GO:0001666; GO:0001892; GO:0003700; GO:0004879; GO:0005634; GO:0005654; GO:0005667; GO:0005737; GO:0006357; GO:0009636; GO:0010575; GO:0016604; GO:0017162; GO:0030154; GO:0033235; GO:0034751; GO:0034753; GO:0042803; GO:0043565; GO:0043619; GO:0044877; GO:0045893; GO:0045944; GO:0046886; GO:0046982; GO:0061629; GO:0090575; GO:1990837 30221 XM_044307413.1 50 122 20 30 35 NA NA NA NA NA NA 30222 XM_044308887.1 12 69 19 103 0 Q8C8R3 3.08e-94 Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) Mus musculus (Mouse) atrial cardiac muscle cell action potential [GO:0086014]; atrial cardiac muscle cell to AV node cell communication [GO:0086066]; atrial septum development [GO:0003283]; cardiac muscle contraction [GO:0060048]; cellular calcium ion homeostasis [GO:0006874]; endocytosis [GO:0006897]; positive regulation of calcium ion transmembrane transporter activity [GO:1901021]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cation channel activity [GO:2001259]; positive regulation of gene expression [GO:0010628]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to endoplasmic reticulum [GO:0070972]; protein localization to M-band [GO:0036309]; protein localization to organelle [GO:0033365]; protein localization to plasma membrane [GO:0072659]; protein localization to T-tubule [GO:0036371]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; regulation of atrial cardiac muscle cell action potential [GO:0098910]; regulation of AV node cell action potential [GO:0098904]; regulation of calcium ion transmembrane transporter activity [GO:1901019]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cardiac muscle cell membrane potential [GO:0086036]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cation channel activity [GO:2001257]; regulation of heart rate [GO:0002027]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of protein stability [GO:0031647]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of SA node cell action potential [GO:0098907]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; SA node cell action potential [GO:0086015]; SA node cell to atrial cardiac muscle cell communication [GO:0086070]; T-tubule organization [GO:0033292]; ventricular cardiac muscle cell action potential [GO:0086005] GO:0002027; GO:0003283; GO:0005200; GO:0005737; GO:0005739; GO:0005764; GO:0005769; GO:0005856; GO:0005886; GO:0006874; GO:0006897; GO:0008104; GO:0010628; GO:0010881; GO:0010882; GO:0014069; GO:0014704; GO:0015031; GO:0015459; GO:0016323; GO:0019899; GO:0019901; GO:0030018; GO:0030315; GO:0030507; GO:0030674; GO:0031234; GO:0031430; GO:0031647; GO:0031672; GO:0033010; GO:0033292; GO:0033365; GO:0034394; GO:0036309; GO:0036371; GO:0042383; GO:0043005; GO:0043034; GO:0043268; GO:0044325; GO:0045121; GO:0045211; GO:0048471; GO:0050821; GO:0051117; GO:0051279; GO:0051924; GO:0051928; GO:0055037; GO:0055117; GO:0060048; GO:0060307; GO:0070972; GO:0072659; GO:0086004; GO:0086005; GO:0086014; GO:0086015; GO:0086036; GO:0086066; GO:0086070; GO:0086091; GO:0098904; GO:0098907; GO:0098910; GO:0140031; GO:1901018; GO:1901019; GO:1901021; GO:2001257; GO:2001259 30223 XM_044308887.1 12 69 19 103 0 Q8C8R3 3.14e-88 Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) Mus musculus (Mouse) atrial cardiac muscle cell action potential [GO:0086014]; atrial cardiac muscle cell to AV node cell communication [GO:0086066]; atrial septum development [GO:0003283]; cardiac muscle contraction [GO:0060048]; cellular calcium ion homeostasis [GO:0006874]; endocytosis [GO:0006897]; positive regulation of calcium ion transmembrane transporter activity [GO:1901021]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cation channel activity [GO:2001259]; positive regulation of gene expression [GO:0010628]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to endoplasmic reticulum [GO:0070972]; protein localization to M-band [GO:0036309]; protein localization to organelle [GO:0033365]; protein localization to plasma membrane [GO:0072659]; protein localization to T-tubule [GO:0036371]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; regulation of atrial cardiac muscle cell action potential [GO:0098910]; regulation of AV node cell action potential [GO:0098904]; regulation of calcium ion transmembrane transporter activity [GO:1901019]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cardiac muscle cell membrane potential [GO:0086036]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cation channel activity [GO:2001257]; regulation of heart rate [GO:0002027]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of protein stability [GO:0031647]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of SA node cell action potential [GO:0098907]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; SA node cell action potential [GO:0086015]; SA node cell to atrial cardiac muscle cell communication [GO:0086070]; T-tubule organization [GO:0033292]; ventricular cardiac muscle cell action potential [GO:0086005] GO:0002027; GO:0003283; GO:0005200; GO:0005737; GO:0005739; GO:0005764; GO:0005769; GO:0005856; GO:0005886; GO:0006874; GO:0006897; GO:0008104; GO:0010628; GO:0010881; GO:0010882; GO:0014069; GO:0014704; GO:0015031; GO:0015459; GO:0016323; GO:0019899; GO:0019901; GO:0030018; GO:0030315; GO:0030507; GO:0030674; GO:0031234; GO:0031430; GO:0031647; GO:0031672; GO:0033010; GO:0033292; GO:0033365; GO:0034394; GO:0036309; GO:0036371; GO:0042383; GO:0043005; GO:0043034; GO:0043268; GO:0044325; GO:0045121; GO:0045211; GO:0048471; GO:0050821; GO:0051117; GO:0051279; GO:0051924; GO:0051928; GO:0055037; GO:0055117; GO:0060048; GO:0060307; GO:0070972; GO:0072659; GO:0086004; GO:0086005; GO:0086014; GO:0086015; GO:0086036; GO:0086066; GO:0086070; GO:0086091; GO:0098904; GO:0098907; GO:0098910; GO:0140031; GO:1901018; GO:1901019; GO:1901021; GO:2001257; GO:2001259 30224 XM_044308887.1 12 69 19 103 0 Q8C8R3 7.16e-86 Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) Mus musculus (Mouse) atrial cardiac muscle cell action potential [GO:0086014]; atrial cardiac muscle cell to AV node cell communication [GO:0086066]; atrial septum development [GO:0003283]; cardiac muscle contraction [GO:0060048]; cellular calcium ion homeostasis [GO:0006874]; endocytosis [GO:0006897]; positive regulation of calcium ion transmembrane transporter activity [GO:1901021]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cation channel activity [GO:2001259]; positive regulation of gene expression [GO:0010628]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to endoplasmic reticulum [GO:0070972]; protein localization to M-band [GO:0036309]; protein localization to organelle [GO:0033365]; protein localization to plasma membrane [GO:0072659]; protein localization to T-tubule [GO:0036371]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; regulation of atrial cardiac muscle cell action potential [GO:0098910]; regulation of AV node cell action potential [GO:0098904]; regulation of calcium ion transmembrane transporter activity [GO:1901019]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cardiac muscle cell membrane potential [GO:0086036]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cation channel activity [GO:2001257]; regulation of heart rate [GO:0002027]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of protein stability [GO:0031647]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of SA node cell action potential [GO:0098907]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; SA node cell action potential [GO:0086015]; SA node cell to atrial cardiac muscle cell communication [GO:0086070]; T-tubule organization [GO:0033292]; ventricular cardiac muscle cell action potential [GO:0086005] GO:0002027; GO:0003283; GO:0005200; GO:0005737; GO:0005739; GO:0005764; GO:0005769; GO:0005856; GO:0005886; GO:0006874; GO:0006897; GO:0008104; GO:0010628; GO:0010881; GO:0010882; GO:0014069; GO:0014704; GO:0015031; GO:0015459; GO:0016323; GO:0019899; GO:0019901; GO:0030018; GO:0030315; GO:0030507; GO:0030674; GO:0031234; GO:0031430; GO:0031647; GO:0031672; GO:0033010; GO:0033292; GO:0033365; GO:0034394; GO:0036309; GO:0036371; GO:0042383; GO:0043005; GO:0043034; GO:0043268; GO:0044325; GO:0045121; GO:0045211; GO:0048471; GO:0050821; GO:0051117; GO:0051279; GO:0051924; GO:0051928; GO:0055037; GO:0055117; GO:0060048; GO:0060307; GO:0070972; GO:0072659; GO:0086004; GO:0086005; GO:0086014; GO:0086015; GO:0086036; GO:0086066; GO:0086070; GO:0086091; GO:0098904; GO:0098907; GO:0098910; GO:0140031; GO:1901018; GO:1901019; GO:1901021; GO:2001257; GO:2001259 30225 XM_044308887.1 12 69 19 103 0 Q8C8R3 2.07e-75 Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) Mus musculus (Mouse) atrial cardiac muscle cell action potential [GO:0086014]; atrial cardiac muscle cell to AV node cell communication [GO:0086066]; atrial septum development [GO:0003283]; cardiac muscle contraction [GO:0060048]; cellular calcium ion homeostasis [GO:0006874]; endocytosis [GO:0006897]; positive regulation of calcium ion transmembrane transporter activity [GO:1901021]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cation channel activity [GO:2001259]; positive regulation of gene expression [GO:0010628]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to endoplasmic reticulum [GO:0070972]; protein localization to M-band [GO:0036309]; protein localization to organelle [GO:0033365]; protein localization to plasma membrane [GO:0072659]; protein localization to T-tubule [GO:0036371]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; regulation of atrial cardiac muscle cell action potential [GO:0098910]; regulation of AV node cell action potential [GO:0098904]; regulation of calcium ion transmembrane transporter activity [GO:1901019]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cardiac muscle cell membrane potential [GO:0086036]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cation channel activity [GO:2001257]; regulation of heart rate [GO:0002027]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of protein stability [GO:0031647]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of SA node cell action potential [GO:0098907]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; SA node cell action potential [GO:0086015]; SA node cell to atrial cardiac muscle cell communication [GO:0086070]; T-tubule organization [GO:0033292]; ventricular cardiac muscle cell action potential [GO:0086005] GO:0002027; GO:0003283; GO:0005200; GO:0005737; GO:0005739; GO:0005764; GO:0005769; GO:0005856; GO:0005886; GO:0006874; GO:0006897; GO:0008104; GO:0010628; GO:0010881; GO:0010882; GO:0014069; GO:0014704; GO:0015031; GO:0015459; GO:0016323; GO:0019899; GO:0019901; GO:0030018; GO:0030315; GO:0030507; GO:0030674; GO:0031234; GO:0031430; GO:0031647; GO:0031672; GO:0033010; GO:0033292; GO:0033365; GO:0034394; GO:0036309; GO:0036371; GO:0042383; GO:0043005; GO:0043034; GO:0043268; GO:0044325; GO:0045121; GO:0045211; GO:0048471; GO:0050821; GO:0051117; GO:0051279; GO:0051924; GO:0051928; GO:0055037; GO:0055117; GO:0060048; GO:0060307; GO:0070972; GO:0072659; GO:0086004; GO:0086005; GO:0086014; GO:0086015; GO:0086036; GO:0086066; GO:0086070; GO:0086091; GO:0098904; GO:0098907; GO:0098910; GO:0140031; GO:1901018; GO:1901019; GO:1901021; GO:2001257; GO:2001259 30226 XM_044308887.1 12 69 19 103 0 Q8C8R3 9.41e-61 Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) Mus musculus (Mouse) atrial cardiac muscle cell action potential [GO:0086014]; atrial cardiac muscle cell to AV node cell communication [GO:0086066]; atrial septum development [GO:0003283]; cardiac muscle contraction [GO:0060048]; cellular calcium ion homeostasis [GO:0006874]; endocytosis [GO:0006897]; positive regulation of calcium ion transmembrane transporter activity [GO:1901021]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cation channel activity [GO:2001259]; positive regulation of gene expression [GO:0010628]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to endoplasmic reticulum [GO:0070972]; protein localization to M-band [GO:0036309]; protein localization to organelle [GO:0033365]; protein localization to plasma membrane [GO:0072659]; protein localization to T-tubule [GO:0036371]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; regulation of atrial cardiac muscle cell action potential [GO:0098910]; regulation of AV node cell action potential [GO:0098904]; regulation of calcium ion transmembrane transporter activity [GO:1901019]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cardiac muscle cell membrane potential [GO:0086036]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cation channel activity [GO:2001257]; regulation of heart rate [GO:0002027]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of protein stability [GO:0031647]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of SA node cell action potential [GO:0098907]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; SA node cell action potential [GO:0086015]; SA node cell to atrial cardiac muscle cell communication [GO:0086070]; T-tubule organization [GO:0033292]; ventricular cardiac muscle cell action potential [GO:0086005] GO:0002027; GO:0003283; GO:0005200; GO:0005737; GO:0005739; GO:0005764; GO:0005769; GO:0005856; GO:0005886; GO:0006874; GO:0006897; GO:0008104; GO:0010628; GO:0010881; GO:0010882; GO:0014069; GO:0014704; GO:0015031; GO:0015459; GO:0016323; GO:0019899; GO:0019901; GO:0030018; GO:0030315; GO:0030507; GO:0030674; GO:0031234; GO:0031430; GO:0031647; GO:0031672; GO:0033010; GO:0033292; GO:0033365; GO:0034394; GO:0036309; GO:0036371; GO:0042383; GO:0043005; GO:0043034; GO:0043268; GO:0044325; GO:0045121; GO:0045211; GO:0048471; GO:0050821; GO:0051117; GO:0051279; GO:0051924; GO:0051928; GO:0055037; GO:0055117; GO:0060048; GO:0060307; GO:0070972; GO:0072659; GO:0086004; GO:0086005; GO:0086014; GO:0086015; GO:0086036; GO:0086066; GO:0086070; GO:0086091; GO:0098904; GO:0098907; GO:0098910; GO:0140031; GO:1901018; GO:1901019; GO:1901021; GO:2001257; GO:2001259 30227 XM_044308887.1 12 69 19 103 0 Q8C8R3 3.71e-52 Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) Mus musculus (Mouse) atrial cardiac muscle cell action potential [GO:0086014]; atrial cardiac muscle cell to AV node cell communication [GO:0086066]; atrial septum development [GO:0003283]; cardiac muscle contraction [GO:0060048]; cellular calcium ion homeostasis [GO:0006874]; endocytosis [GO:0006897]; positive regulation of calcium ion transmembrane transporter activity [GO:1901021]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cation channel activity [GO:2001259]; positive regulation of gene expression [GO:0010628]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to endoplasmic reticulum [GO:0070972]; protein localization to M-band [GO:0036309]; protein localization to organelle [GO:0033365]; protein localization to plasma membrane [GO:0072659]; protein localization to T-tubule [GO:0036371]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; regulation of atrial cardiac muscle cell action potential [GO:0098910]; regulation of AV node cell action potential [GO:0098904]; regulation of calcium ion transmembrane transporter activity [GO:1901019]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cardiac muscle cell membrane potential [GO:0086036]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cation channel activity [GO:2001257]; regulation of heart rate [GO:0002027]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of protein stability [GO:0031647]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of SA node cell action potential [GO:0098907]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; SA node cell action potential [GO:0086015]; SA node cell to atrial cardiac muscle cell communication [GO:0086070]; T-tubule organization [GO:0033292]; ventricular cardiac muscle cell action potential [GO:0086005] GO:0002027; GO:0003283; GO:0005200; GO:0005737; GO:0005739; GO:0005764; GO:0005769; GO:0005856; GO:0005886; GO:0006874; GO:0006897; GO:0008104; GO:0010628; GO:0010881; GO:0010882; GO:0014069; GO:0014704; GO:0015031; GO:0015459; GO:0016323; GO:0019899; GO:0019901; GO:0030018; GO:0030315; GO:0030507; GO:0030674; GO:0031234; GO:0031430; GO:0031647; GO:0031672; GO:0033010; GO:0033292; GO:0033365; GO:0034394; GO:0036309; GO:0036371; GO:0042383; GO:0043005; GO:0043034; GO:0043268; GO:0044325; GO:0045121; GO:0045211; GO:0048471; GO:0050821; GO:0051117; GO:0051279; GO:0051924; GO:0051928; GO:0055037; GO:0055117; GO:0060048; GO:0060307; GO:0070972; GO:0072659; GO:0086004; GO:0086005; GO:0086014; GO:0086015; GO:0086036; GO:0086066; GO:0086070; GO:0086091; GO:0098904; GO:0098907; GO:0098910; GO:0140031; GO:1901018; GO:1901019; GO:1901021; GO:2001257; GO:2001259 30228 XM_029344066.2 51 36 19 81 53 NA NA NA NA NA NA 30229 XM_029346699.2 1373 1484 342 866 669 O93479 5.34e-166 Origin recognition complex subunit 4 Xenopus laevis (African clawed frog) DNA replication [GO:0006260] GO:0003677; GO:0005524; GO:0005664; GO:0006260 30230 XM_029333012.2 4 10 0 0 0 NA NA NA NA NA NA 30231 XM_029351437.2 254 322 130 649 872 NA NA NA NA NA NA 30232 XM_044315601.1 1 16 20 1 19 NA NA NA NA NA NA 30233 XM_029337871.2 2 83 25 79 43 NA NA NA NA NA NA 30234 XM_044314774.1 0 0 0 0 7 Q9M2U3 9.05e-33 Protein ALP1-like (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) NA GO:0000118; GO:0004518; GO:0046872 30235 XM_044319941.1 12 12 6 11 29 O34313 9.65e-36 Trifunctional nucleotide phosphoesterase protein YfkN [Includes: 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase (EC 3.1.3.6) (EC 3.1.4.16); 5'-nucleotidase (EC 3.1.3.5)] Bacillus subtilis (strain 168) nucleotide catabolic process [GO:0009166] GO:0000166; GO:0005576; GO:0008254; GO:0008663; GO:0009166; GO:0030288; GO:0046872; GO:0106411 30236 XM_029356742.2 2082 998 1204 2013 1787 O35551 3.07e-47 Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) Mus musculus (Mouse) apoptotic process [GO:0006915]; endocytosis [GO:0006897]; Golgi to plasma membrane transport [GO:0006893]; protein localization to ciliary membrane [GO:1903441]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] GO:0005096; GO:0005768; GO:0005769; GO:0006893; GO:0006897; GO:0006915; GO:0008083; GO:0015031; GO:0016192; GO:0019904; GO:0030139; GO:0032991; GO:0042803; GO:0043231; GO:0055037; GO:0099523; GO:1903441 30237 XM_029356742.2 2082 998 1204 2013 1787 O35551 1.31e-22 Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) Mus musculus (Mouse) apoptotic process [GO:0006915]; endocytosis [GO:0006897]; Golgi to plasma membrane transport [GO:0006893]; protein localization to ciliary membrane [GO:1903441]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] GO:0005096; GO:0005768; GO:0005769; GO:0006893; GO:0006897; GO:0006915; GO:0008083; GO:0015031; GO:0016192; GO:0019904; GO:0030139; GO:0032991; GO:0042803; GO:0043231; GO:0055037; GO:0099523; GO:1903441 30238 XM_044324670.1 0 181 253 0 286 Q01484 1.03e-22 Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin) Homo sapiens (Human) atrial cardiac muscle cell action potential [GO:0086014]; atrial cardiac muscle cell to AV node cell communication [GO:0086066]; atrial septum development [GO:0003283]; cellular calcium ion homeostasis [GO:0006874]; endocytosis [GO:0006897]; membrane depolarization during SA node cell action potential [GO:0086046]; paranodal junction assembly [GO:0030913]; positive regulation of calcium ion transmembrane transporter activity [GO:1901021]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cation channel activity [GO:2001259]; positive regulation of gene expression [GO:0010628]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to endoplasmic reticulum [GO:0070972]; protein localization to M-band [GO:0036309]; protein localization to organelle [GO:0033365]; protein localization to plasma membrane [GO:0072659]; protein localization to T-tubule [GO:0036371]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; regulation of atrial cardiac muscle cell action potential [GO:0098910]; regulation of calcium ion transmembrane transporter activity [GO:1901019]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of heart rate [GO:0002027]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of protein stability [GO:0031647]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of SA node cell action potential [GO:0098907]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; response to methylmercury [GO:0051597]; SA node cell action potential [GO:0086015]; SA node cell to atrial cardiac muscle cell communication [GO:0086070]; sarcoplasmic reticulum calcium ion transport [GO:0070296]; T-tubule organization [GO:0033292]; ventricular cardiac muscle cell action potential [GO:0086005] GO:0002027; GO:0003283; GO:0005200; GO:0005739; GO:0005764; GO:0005769; GO:0005829; GO:0005856; GO:0005886; GO:0006874; GO:0006897; GO:0008093; GO:0008104; GO:0010628; GO:0010881; GO:0010882; GO:0014704; GO:0015031; GO:0016323; GO:0016324; GO:0019899; GO:0019901; GO:0030018; GO:0030315; GO:0030507; GO:0030674; GO:0030913; GO:0031430; GO:0031647; GO:0031672; GO:0033292; GO:0033365; GO:0034394; GO:0036309; GO:0036371; GO:0042383; GO:0043005; GO:0043034; GO:0043268; GO:0044325; GO:0045121; GO:0045211; GO:0050821; GO:0051117; GO:0051279; GO:0051597; GO:0051924; GO:0051928; GO:0055037; GO:0055117; GO:0060307; GO:0070296; GO:0070972; GO:0072659; GO:0086004; GO:0086005; GO:0086014; GO:0086015; GO:0086046; GO:0086066; GO:0086070; GO:0086091; GO:0098907; GO:0098910; GO:0140031; GO:1901018; GO:1901019; GO:1901021; GO:2001259 30239 XM_044324670.1 0 181 253 0 286 Q01484 9.42e-21 Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin) Homo sapiens (Human) atrial cardiac muscle cell action potential [GO:0086014]; atrial cardiac muscle cell to AV node cell communication [GO:0086066]; atrial septum development [GO:0003283]; cellular calcium ion homeostasis [GO:0006874]; endocytosis [GO:0006897]; membrane depolarization during SA node cell action potential [GO:0086046]; paranodal junction assembly [GO:0030913]; positive regulation of calcium ion transmembrane transporter activity [GO:1901021]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cation channel activity [GO:2001259]; positive regulation of gene expression [GO:0010628]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to endoplasmic reticulum [GO:0070972]; protein localization to M-band [GO:0036309]; protein localization to organelle [GO:0033365]; protein localization to plasma membrane [GO:0072659]; protein localization to T-tubule [GO:0036371]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; regulation of atrial cardiac muscle cell action potential [GO:0098910]; regulation of calcium ion transmembrane transporter activity [GO:1901019]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of heart rate [GO:0002027]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of protein stability [GO:0031647]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of SA node cell action potential [GO:0098907]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; response to methylmercury [GO:0051597]; SA node cell action potential [GO:0086015]; SA node cell to atrial cardiac muscle cell communication [GO:0086070]; sarcoplasmic reticulum calcium ion transport [GO:0070296]; T-tubule organization [GO:0033292]; ventricular cardiac muscle cell action potential [GO:0086005] GO:0002027; GO:0003283; GO:0005200; GO:0005739; GO:0005764; GO:0005769; GO:0005829; GO:0005856; GO:0005886; GO:0006874; GO:0006897; GO:0008093; GO:0008104; GO:0010628; GO:0010881; GO:0010882; GO:0014704; GO:0015031; GO:0016323; GO:0016324; GO:0019899; GO:0019901; GO:0030018; GO:0030315; GO:0030507; GO:0030674; GO:0030913; GO:0031430; GO:0031647; GO:0031672; GO:0033292; GO:0033365; GO:0034394; GO:0036309; GO:0036371; GO:0042383; GO:0043005; GO:0043034; GO:0043268; GO:0044325; GO:0045121; GO:0045211; GO:0050821; GO:0051117; GO:0051279; GO:0051597; GO:0051924; GO:0051928; GO:0055037; GO:0055117; GO:0060307; GO:0070296; GO:0070972; GO:0072659; GO:0086004; GO:0086005; GO:0086014; GO:0086015; GO:0086046; GO:0086066; GO:0086070; GO:0086091; GO:0098907; GO:0098910; GO:0140031; GO:1901018; GO:1901019; GO:1901021; GO:2001259 30240 XM_044324301.1 5739 4357 1418 7176 5915 NA NA NA NA NA NA 30241 XM_029356369.2 73 40 82 0 307 P55112 4.69e-37 Zinc metalloproteinase nas-4 (EC 3.4.24.-) (Nematode astacin 4) Caenorhabditis elegans proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0006508; GO:0008270 30242 XM_029336005.2 248 623 28 268 122 O94443 1.13e-63 Uncharacterized exonuclease C637.09 (EC 3.1.-.-) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; tRNA 3'-trailer cleavage, exonucleolytic [GO:0034415]; U5 snRNA 3'-end processing [GO:0034476] GO:0000175; GO:0000467; GO:0003676; GO:0004527; GO:0005634; GO:0034415; GO:0034476 30243 XM_029325342.2 102 58 54 31 56 NA NA NA NA NA NA 30244 XM_044320969.1 0 119 27 97 55 NA NA NA NA NA NA 30245 XR_006394698.1 0 0 0 0 21 NA NA NA NA NA NA 30246 XM_044327180.1 680 619 481 720 728 NA NA NA NA NA NA 30247 XM_044306831.1 0 11 4 0 31 NA NA NA NA NA NA 30248 XM_044328589.1 252 616 113 310 300 NA NA NA NA NA NA 30249 XM_029332238.2 445 257 294 272 439 Q66JG5 4.76e-97 Transcriptional adapter 3 (ADA3 homolog) (Transcriptional adapter 3-like) (ADA3-like protein) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005634 30250 XM_029331933.2 437 32 51 240 172 P02467 3.39e-62 Collagen alpha-2(I) chain (Alpha-2 type I collagen) Gallus gallus (Chicken) extracellular matrix organization [GO:0030198] GO:0005201; GO:0005583; GO:0005584; GO:0005615; GO:0030198; GO:0031012; GO:0046872 30251 XM_029338819.2 583 404 501 535 594 Q96QT6 4.25e-73 PHD finger protein 12 (PHD factor 1) (Pf1) Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0001222; GO:0003714; GO:0005634; GO:0005654; GO:0006357; GO:0016580; GO:0017053; GO:0035091; GO:0045892; GO:0046872; GO:0070822 30252 XM_029338819.2 583 404 501 535 594 Q96QT6 2.16e-48 PHD finger protein 12 (PHD factor 1) (Pf1) Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0001222; GO:0003714; GO:0005634; GO:0005654; GO:0006357; GO:0016580; GO:0017053; GO:0035091; GO:0045892; GO:0046872; GO:0070822 30253 XM_044325530.1 25 77 53 0 0 B1AS29 1.46e-82 Glutamate receptor ionotropic, kainate 3 (GluK3) (Glutamate receptor 7) (GluR-7) (GluR7) Mus musculus (Mouse) G protein-coupled glutamate receptor signaling pathway [GO:0007216]; glutamate receptor signaling pathway [GO:0007215]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; regulation of membrane potential [GO:0042391]; synaptic transmission, glutamatergic [GO:0035249] GO:0001640; GO:0004970; GO:0005886; GO:0007215; GO:0007216; GO:0008066; GO:0015276; GO:0015277; GO:0030424; GO:0030425; GO:0032839; GO:0032983; GO:0035249; GO:0038023; GO:0042391; GO:0042734; GO:0043195; GO:0043204; GO:0045211; GO:0050804; GO:0051967; GO:0098978; GO:0099507; GO:1904315 30254 XM_029345220.2 48 0 40 21 102 NA NA NA NA NA NA 30255 XM_044321393.1 5 1 2 3 7 NA NA NA NA NA NA 30256 XM_029344929.2 27 35 10 58 39 NA NA NA NA NA NA 30257 XM_044321628.1 0 0 0 0 69 P69478 4.95e-40 Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4S-1) (C4ST-1) (C4ST1) Rattus norvegicus (Rat) apoptotic process [GO:0006915]; carbohydrate biosynthetic process [GO:0016051]; cartilage development [GO:0051216]; chondrocyte development [GO:0002063]; chondroitin sulfate biosynthetic process [GO:0030206]; chondroitin sulfate metabolic process [GO:0030204]; developmental growth [GO:0048589]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; embryonic viscerocranium morphogenesis [GO:0048703]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; polysaccharide localization [GO:0033037]; post-anal tail morphogenesis [GO:0036342]; post-embryonic development [GO:0009791]; proteoglycan biosynthetic process [GO:0030166]; regulation of cell population proliferation [GO:0042127]; respiratory gaseous exchange by respiratory system [GO:0007585]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0000139; GO:0001537; GO:0001701; GO:0002063; GO:0006915; GO:0007179; GO:0007585; GO:0008146; GO:0009791; GO:0016051; GO:0030166; GO:0030204; GO:0030206; GO:0030326; GO:0030512; GO:0033037; GO:0036342; GO:0042127; GO:0042733; GO:0043066; GO:0047756; GO:0048589; GO:0048703; GO:0048704; GO:0050659; GO:0051216 30258 XM_044316400.1 1497 884 954 2686 2366 Q7YU29 2.35e-171 Dystrophin, isoform E (Protein detached) Drosophila melanogaster (Fruit fly) actin cytoskeleton organization [GO:0030036]; establishment of cell polarity [GO:0030010]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; imaginal disc-derived wing vein specification [GO:0007474]; maintenance of presynaptic active zone structure [GO:0048790]; muscle cell cellular homeostasis [GO:0046716]; muscle cell development [GO:0055001]; muscle organ development [GO:0007517]; neuromuscular synaptic transmission [GO:0007274]; regulation of neurotransmitter secretion [GO:0046928]; regulation of short-term neuronal synaptic plasticity [GO:0048172] GO:0005737; GO:0005856; GO:0005886; GO:0005938; GO:0007274; GO:0007474; GO:0007517; GO:0008270; GO:0008307; GO:0008586; GO:0016010; GO:0030010; GO:0030018; GO:0030036; GO:0030054; GO:0030864; GO:0031594; GO:0042383; GO:0042995; GO:0045202; GO:0046716; GO:0046928; GO:0048172; GO:0048790; GO:0050699; GO:0051015; GO:0055001 30259 XR_006391406.1 194 62 72 272 476 NA NA NA NA NA NA 30260 XM_029324547.2 375 0 84 236 422 Q9N294 5.06e-24 Beta-1,3-galactosyltransferase 5 (Beta-1,3-GalTase 5) (Beta3Gal-T5) (Beta3GalT5) (b3Gal-T5) (EC 2.4.1.-) (Beta-3-Gx-T5) (UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 5) (UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 5) Pan paniscus (Pygmy chimpanzee) (Bonobo) lipid metabolic process [GO:0006629]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0006629; GO:0016758 30261 XM_044315480.1 27 1 11 77 47 NA NA NA NA NA NA 30262 XM_044308033.1 67 69 79 429 0 B3EWZ3 8.57e-93 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 30263 XM_044308033.1 67 69 79 429 0 B3EWZ3 2.96e-85 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 30264 XM_044308033.1 67 69 79 429 0 B3EWZ3 2.26e-68 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 30265 XM_044308033.1 67 69 79 429 0 B3EWZ3 4.3e-68 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 30266 XM_044308033.1 67 69 79 429 0 B3EWZ3 1.94e-58 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 30267 XM_044309487.1 9 40 20 29 10 NA NA NA NA NA NA 30268 XM_029358468.2 798 663 381 562 263 Q9BX70 0 BTB/POZ domain-containing protein 2 Homo sapiens (Human) neurogenesis [GO:0022008] GO:0000932; GO:0005829; GO:0022008 30269 XR_003827858.2 1712 184 751 20 56 NA NA NA NA NA NA 30270 XM_029336009.2 25 0 25 174 55 Q01528 2.04e-22 Hemagglutinin/amebocyte aggregation factor (18K-LAF) Limulus polyphemus (Atlantic horseshoe crab) NA GO:0005576 30271 XM_044318610.1 19 5 6 23 18 NA NA NA NA NA NA 30272 XM_029339617.2 449 296 310 493 356 NA NA NA NA NA NA 30273 XM_044325647.1 1921 1655 410 1278 1239 NA NA NA NA NA NA 30274 XM_044327997.1 368 2 109 0 291 NA NA NA NA NA NA 30275 XM_029332649.2 0 155 0 0 0 P49337 2.57e-67 Protein Wnt-4 Gallus gallus (Chicken) canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; kidney morphogenesis [GO:0060993]; negative regulation of androgen biosynthetic process [GO:2000180]; neuron differentiation [GO:0030182]; positive regulation of cartilage development [GO:0061036]; positive regulation of skeletal muscle cell proliferation [GO:0014858]; positive regulation of skeletal muscle fiber differentiation [GO:1902811] GO:0005109; GO:0005125; GO:0005615; GO:0005737; GO:0014858; GO:0030182; GO:0045165; GO:0060070; GO:0060993; GO:0061036; GO:1902811; GO:2000180 30276 XM_029336262.2 1178 1705 512 991 591 NA NA NA NA NA NA 30277 XM_044318968.1 177 191 194 157 196 NA NA NA NA NA NA 30278 XM_044318450.1 1 2 46 4 26 NA NA NA NA NA NA 30279 XM_044313991.1 17 0 11 6 29 NA NA NA NA NA NA 30280 XM_044325251.1 341 125 77 64 424 NA NA NA NA NA NA 30281 XM_029339525.2 434 206 83 70 86 NA NA NA NA NA NA 30282 XM_029339601.2 614 451 441 553 428 Q9W676 3.31e-122 LIM domain-binding protein 2 (LDB-2) (Carboxyl-terminal LIM domain-binding protein 1) (CLIM-1) (LIM domain-binding factor CLIM1) (cLdb2) Gallus gallus (Chicken) negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000122; GO:0005634; GO:0005667; GO:0007399; GO:0030274; GO:0045944 30283 XM_029339106.2 1410 1014 643 874 842 E9Q4F2 0 Kelch-like protein 18 Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; positive regulation of mitotic cell cycle phase transition [GO:1901992]; protein ubiquitination [GO:0016567] GO:0007049; GO:0016567; GO:0051301; GO:1901992 30284 XR_006395449.1 3 0 11 22 23 NA NA NA NA NA NA 30285 XR_006398074.1 217 29 73 116 65 NA NA NA NA NA NA 30286 XM_044325776.1 58 0 11 14 12 Q8K3Z0 2.92e-28 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 30287 XM_044307501.1 0 13 0 0 1 NA NA NA NA NA NA 30288 XM_029329158.2 759 398 351 1358 1212 A0FI79 2.51e-112 Phosphatidylinositol polyphosphate 5-phosphatase type IV (72 kDa inositol polyphosphate 5-phosphatase) (Inositol polyphosphate-5-phosphatase E) (Phosphatidylinositol 4,5-bisphosphate 5-phosphatase) (EC 3.1.3.36) (Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase) (EC 3.1.3.86) Pan troglodytes (Chimpanzee) phosphatidylinositol dephosphorylation [GO:0046856] GO:0001726; GO:0004439; GO:0004445; GO:0005634; GO:0005794; GO:0005886; GO:0005930; GO:0032580; GO:0034485; GO:0046856 30289 XM_029356815.2 57 100 137 0 172 NA NA NA NA NA NA 30290 XM_029346642.2 1026 899 615 569 432 Q13572 1.07e-86 Inositol-tetrakisphosphate 1-kinase (EC 2.7.1.134) (Inositol 1,3,4-trisphosphate 5/6-kinase) (Inositol-triphosphate 5/6-kinase) (Ins(1,3,4)P(3) 5/6-kinase) (EC 2.7.1.159) Homo sapiens (Human) blood coagulation [GO:0007596]; inositol phosphorylation [GO:0052746]; inositol trisphosphate metabolic process [GO:0032957]; necroptotic process [GO:0070266]; neural tube development [GO:0021915]; signal transduction [GO:0007165] GO:0000287; GO:0000825; GO:0003824; GO:0005524; GO:0005829; GO:0007165; GO:0007596; GO:0016324; GO:0016787; GO:0016853; GO:0021915; GO:0032957; GO:0047325; GO:0052725; GO:0052726; GO:0052746; GO:0070266 30291 XM_044308371.1 9 0 22 1 12 NA NA NA NA NA NA 30292 XM_044322962.1 171 163 109 151 56 NA NA NA NA NA NA 30293 XM_029357462.2 197 10 11 18 24 NA NA NA NA NA NA 30294 XM_029354173.2 1548 594 849 924 951 Q1ZXJ0 2.23e-112 Chloride channel protein D Dictyostelium discoideum (Social amoeba) regulation of ion transmembrane transport [GO:0034765]; sorocarp development [GO:0030587] GO:0005247; GO:0015108; GO:0030587; GO:0034707; GO:0034765; GO:0043231 30295 XR_006391748.1 351 19 103 138 153 NA NA NA NA NA NA 30296 XR_006392644.1 22 2 15 3 19 NA NA NA NA NA NA 30297 XM_044310764.1 69 0 5 103 49 Q8BKH7 7.85e-96 Target of rapamycin complex 2 subunit MAPKAP1 (TORC2 subunit MAPKAP1) (Mitogen-activated protein kinase 2-associated protein 1) (Stress-activated map kinase-interacting protein 1) (SAPK-interacting protein 1) Mus musculus (Mouse) cellular response to nutrient levels [GO:0031669]; cytoskeleton organization [GO:0007010]; negative regulation of apoptotic process [GO:0043066]; negative regulation of Ras protein signal transduction [GO:0046580]; phosphorylation [GO:0016310]; positive regulation of cell growth [GO:0030307]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; regulation of cellular response to oxidative stress [GO:1900407]; TORC2 signaling [GO:0038203] GO:0005546; GO:0005547; GO:0005654; GO:0005737; GO:0005794; GO:0005829; GO:0005886; GO:0007010; GO:0016310; GO:0019901; GO:0030307; GO:0031267; GO:0031410; GO:0031669; GO:0031932; GO:0033138; GO:0038203; GO:0043066; GO:0043325; GO:0046580; GO:0060090; GO:0070300; GO:0080025; GO:1900407 30298 XM_029323892.2 483 345 190 326 351 Q6DHJ3 5.26e-150 Cholesterol 7-desaturase nvd (EC 1.14.19.21) (Protein neverland) (Nvd protein) (nvd-Dr) Danio rerio (Zebrafish) (Brachydanio rerio) cholesterol metabolic process [GO:0008203] GO:0005737; GO:0008203; GO:0016020; GO:0016491; GO:0046872; GO:0051537 30299 XR_003828373.2 1 0 1 0 10 NA NA NA NA NA NA 30300 XM_044315397.1 13 0 2 5 4 NA NA NA NA NA NA 30301 XM_044324825.1 0 0 1 0 28 NA NA NA NA NA NA 30302 XM_044326951.1 78 140 6 0 32 NA NA NA NA NA NA 30303 XM_044324504.1 0 21 82 14 0 NA NA NA NA NA NA 30304 XR_003824677.2 12 5 4 21 26 NA NA NA NA NA NA 30305 XM_029334638.2 5 9 1 5 3 Q60HE9 5.39e-113 Lysosomal alpha-mannosidase (Laman) (EC 3.2.1.24) (Lysosomal acid alpha-mannosidase) (Mannosidase alpha class 2B member 1) (Mannosidase alpha-B) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) mannose metabolic process [GO:0006013] GO:0004559; GO:0005764; GO:0006013; GO:0030246; GO:0046872 30306 XM_044309314.1 1 8 6 0 28 NA NA NA NA NA NA 30307 XM_029341653.2 18 53 0 11 42 A7MCS3 3.86e-29 UPF0764 protein C16orf89 homolog Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005576; GO:0005829; GO:0016020 30308 XM_029338026.2 497 271 302 447 520 B3EWY9 6.8e-42 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 30309 XR_006396820.1 9 18 0 0 4 P09917 3.92e-77 Polyunsaturated fatty acid 5-lipoxygenase (EC 1.13.11.-) (Arachidonate 5-lipoxygenase) (5-LO) (5-lipoxygenase) (EC 1.13.11.34) Homo sapiens (Human) arachidonic acid metabolic process [GO:0019369]; dendritic cell migration [GO:0036336]; glucose homeostasis [GO:0042593]; hepoxilin biosynthetic process [GO:0051122]; humoral immune response [GO:0006959]; leukocyte chemotaxis involved in inflammatory response [GO:0002232]; leukocyte migration involved in inflammatory response [GO:0002523]; leukotriene A4 biosynthetic process [GO:1901753]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; leukotriene production involved in inflammatory response [GO:0002540]; linoleic acid metabolic process [GO:0043651]; lipid oxidation [GO:0034440]; lipoxin biosynthetic process [GO:2001301]; lipoxygenase pathway [GO:0019372]; long-chain fatty acid biosynthetic process [GO:0042759]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of inflammatory response [GO:0050728]; negative regulation of response to endoplasmic reticulum stress [GO:1903573]; negative regulation of sprouting angiogenesis [GO:1903671]; negative regulation of vascular wound healing [GO:0061044]; negative regulation of wound healing [GO:0061045]; positive regulation of bone mineralization [GO:0030501]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; regulation of cellular response to oxidative stress [GO:1900407]; regulation of cytokine production involved in inflammatory response [GO:1900015]; regulation of fat cell differentiation [GO:0045598]; regulation of inflammatory response [GO:0050727]; regulation of inflammatory response to wounding [GO:0106014]; regulation of insulin secretion [GO:0050796]; regulation of reactive oxygen species biosynthetic process [GO:1903426] GO:0001937; GO:0002232; GO:0002523; GO:0002540; GO:0004051; GO:0004052; GO:0005506; GO:0005576; GO:0005615; GO:0005635; GO:0005641; GO:0005654; GO:0005829; GO:0006691; GO:0006959; GO:0016363; GO:0016525; GO:0016702; GO:0016787; GO:0019369; GO:0019370; GO:0019372; GO:0030501; GO:0031965; GO:0034440; GO:0034774; GO:0036336; GO:0036403; GO:0042593; GO:0042759; GO:0043651; GO:0045598; GO:0048471; GO:0050727; GO:0050728; GO:0050796; GO:0051122; GO:0061044; GO:0061045; GO:0106014; GO:1900015; GO:1900407; GO:1901753; GO:1903426; GO:1903573; GO:1903671; GO:1904813; GO:1904999; GO:2001301 30310 XM_044317818.1 842 696 550 724 1132 Q4FAT7 0 Beta-glucuronidase (EC 3.2.1.31) Sus scrofa (Pig) chondroitin sulfate catabolic process [GO:0030207]; glucuronoside catabolic process [GO:0019391]; heparan sulfate proteoglycan catabolic process [GO:0030200]; hyaluronan catabolic process [GO:0030214] GO:0004566; GO:0005102; GO:0005615; GO:0019391; GO:0019904; GO:0030200; GO:0030207; GO:0030214; GO:0030246; GO:0043202 30311 XM_029344842.2 0 273 0 235 506 Q9H3L0 6.02e-69 Cobalamin trafficking protein CblD (CblD) (Methylmalonic aciduria and homocystinuria type D protein, mitochondrial) Homo sapiens (Human) cobalamin metabolic process [GO:0009235] GO:0005737; GO:0005739; GO:0005829; GO:0009235 30312 XR_003825977.2 3 3 0 3 6 NA NA NA NA NA NA 30313 XM_029342464.2 30 38 9 19 13 NA NA NA NA NA NA 30314 XM_044316655.1 15 9 21 9 70 NA NA NA NA NA NA 30315 XM_044308282.1 22 0 0 3 0 NA NA NA NA NA NA 30316 XR_003824870.2 28 629 0 9 1 D3Z902 3.81e-49 F-box/WD repeat-containing protein 7 Rattus norvegicus (Rat) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; lung development [GO:0030324]; negative regulation of gene expression [GO:0010629]; negative regulation of osteoclast development [GO:2001205]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; Notch signaling pathway [GO:0007219]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903378]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein destabilization [GO:0031648]; protein K63-linked ubiquitination [GO:0070534]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of cell migration involved in sprouting angiogenesis [GO:0090049]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; sister chromatid cohesion [GO:0007062]; ubiquitin recycling [GO:0010992]; vasculogenesis [GO:0001570] GO:0001570; GO:0005634; GO:0005694; GO:0005730; GO:0005737; GO:0005739; GO:0005783; GO:0005794; GO:0006281; GO:0006974; GO:0007062; GO:0007219; GO:0010629; GO:0010992; GO:0016567; GO:0019005; GO:0030324; GO:0030332; GO:0030674; GO:0031146; GO:0031398; GO:0031625; GO:0031648; GO:0042752; GO:0042802; GO:0043130; GO:0043161; GO:0045741; GO:0048471; GO:0048511; GO:0050816; GO:0050821; GO:0051443; GO:0070374; GO:0070534; GO:0090049; GO:0097027; GO:1901800; GO:1903026; GO:1903146; GO:1903378; GO:1903955; GO:1990452; GO:1990756; GO:2000060; GO:2001205 30317 XR_003824870.2 28 629 0 9 1 D3Z902 1.28e-42 F-box/WD repeat-containing protein 7 Rattus norvegicus (Rat) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; lung development [GO:0030324]; negative regulation of gene expression [GO:0010629]; negative regulation of osteoclast development [GO:2001205]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; Notch signaling pathway [GO:0007219]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903378]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein destabilization [GO:0031648]; protein K63-linked ubiquitination [GO:0070534]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of cell migration involved in sprouting angiogenesis [GO:0090049]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; sister chromatid cohesion [GO:0007062]; ubiquitin recycling [GO:0010992]; vasculogenesis [GO:0001570] GO:0001570; GO:0005634; GO:0005694; GO:0005730; GO:0005737; GO:0005739; GO:0005783; GO:0005794; GO:0006281; GO:0006974; GO:0007062; GO:0007219; GO:0010629; GO:0010992; GO:0016567; GO:0019005; GO:0030324; GO:0030332; GO:0030674; GO:0031146; GO:0031398; GO:0031625; GO:0031648; GO:0042752; GO:0042802; GO:0043130; GO:0043161; GO:0045741; GO:0048471; GO:0048511; GO:0050816; GO:0050821; GO:0051443; GO:0070374; GO:0070534; GO:0090049; GO:0097027; GO:1901800; GO:1903026; GO:1903146; GO:1903378; GO:1903955; GO:1990452; GO:1990756; GO:2000060; GO:2001205 30318 XR_003824870.2 28 629 0 9 1 D3Z902 1.56e-41 F-box/WD repeat-containing protein 7 Rattus norvegicus (Rat) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; lung development [GO:0030324]; negative regulation of gene expression [GO:0010629]; negative regulation of osteoclast development [GO:2001205]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; Notch signaling pathway [GO:0007219]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903378]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein destabilization [GO:0031648]; protein K63-linked ubiquitination [GO:0070534]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of cell migration involved in sprouting angiogenesis [GO:0090049]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; sister chromatid cohesion [GO:0007062]; ubiquitin recycling [GO:0010992]; vasculogenesis [GO:0001570] GO:0001570; GO:0005634; GO:0005694; GO:0005730; GO:0005737; GO:0005739; GO:0005783; GO:0005794; GO:0006281; GO:0006974; GO:0007062; GO:0007219; GO:0010629; GO:0010992; GO:0016567; GO:0019005; GO:0030324; GO:0030332; GO:0030674; GO:0031146; GO:0031398; GO:0031625; GO:0031648; GO:0042752; GO:0042802; GO:0043130; GO:0043161; GO:0045741; GO:0048471; GO:0048511; GO:0050816; GO:0050821; GO:0051443; GO:0070374; GO:0070534; GO:0090049; GO:0097027; GO:1901800; GO:1903026; GO:1903146; GO:1903378; GO:1903955; GO:1990452; GO:1990756; GO:2000060; GO:2001205 30319 XM_029334544.2 4419 3785 4704 3288 2943 NA NA NA NA NA NA 30320 XM_044319415.1 26 12 63 104 51 P53668 7.07e-24 LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1) (KIZ-1) Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; axon extension [GO:0048675]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of axon extension [GO:0045773]; positive regulation of stress fiber assembly [GO:0051496]; protein phosphorylation [GO:0006468]; stress fiber assembly [GO:0043149] GO:0001673; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005925; GO:0006468; GO:0016020; GO:0016607; GO:0030027; GO:0030036; GO:0031072; GO:0032233; GO:0043005; GO:0043149; GO:0044295; GO:0045773; GO:0046872; GO:0048471; GO:0048675; GO:0051444; GO:0051496; GO:0106310 30321 XM_044316944.1 324 194 171 184 189 Q64620 0 Serine/threonine-protein phosphatase 6 catalytic subunit (PP6C) (EC 3.1.3.16) (Protein phosphatase V) (PP-V) Rattus norvegicus (Rat) G1/S transition of mitotic cell cycle [GO:0000082]; innate immune response [GO:0045087]; protein dephosphorylation [GO:0006470] GO:0000082; GO:0004722; GO:0005737; GO:0005739; GO:0005829; GO:0006470; GO:0017018; GO:0045087; GO:0046872 30322 XM_029336853.2 173 65 83 216 332 O00160 0 Unconventional myosin-If (Myosin-Ie) Homo sapiens (Human) actin filament organization [GO:0007015]; vesicle transport along actin filament [GO:0030050] GO:0000146; GO:0003779; GO:0005516; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0005902; GO:0007015; GO:0015629; GO:0016461; GO:0030050; GO:0031982; GO:0051015 30323 XM_044313152.1 92 90 100 106 174 Q68CR1 3.03e-87 Protein sel-1 homolog 3 (Suppressor of lin-12-like protein 3) (Sel-1L3) Homo sapiens (Human) NA GO:0005654; GO:0016020 30324 XM_044324944.1 0 3 1 9 0 NA NA NA NA NA NA 30325 XM_044311635.1 15 99 113 4 56 NA NA NA NA NA NA 30326 XM_044327147.1 37 0 106 65 348 NA NA NA NA NA NA 30327 XR_006391380.1 27 3 32 1 47 NA NA NA NA NA NA 30328 XM_029349615.2 0 0 8 1 8 NA NA NA NA NA NA 30329 XM_029331458.2 20 7 0 130 0 Q6P1A2 7e-101 Lysophospholipid acyltransferase 5 (LPLAT 5) (EC 2.3.1.-) (1-acylglycerophosphocholine O-acyltransferase) (EC 2.3.1.23) (1-acylglycerophosphoethanolamine O-acyltransferase) (EC 2.3.1.n7) (1-acylglycerophosphoserine O-acyltransferase) (EC 2.3.1.n6) (Lysophosphatidylcholine acyltransferase) (LPCAT) (Lyso-PC acyltransferase) (Lysophosphatidylcholine acyltransferase 3) (Lyso-PC acyltransferase 3) (Lysophosphatidylserine acyltransferase) (LPSAT) (Lyso-PS acyltransferase) (Membrane-bound O-acyltransferase domain-containing protein 5) (O-acyltransferase domain-containing protein 5) Homo sapiens (Human) chylomicron assembly [GO:0034378]; endoplasmic reticulum membrane organization [GO:0090158]; intestinal stem cell homeostasis [GO:0036335]; lipid modification [GO:0030258]; negative regulation of inflammatory response [GO:0050728]; negative regulation of response to endoplasmic reticulum stress [GO:1903573]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylcholine biosynthetic process [GO:0006656]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; phosphatidylserine acyl-chain remodeling [GO:0036150]; positive regulation of intestinal cholesterol absorption [GO:0045797]; positive regulation of sterol regulatory element binding protein cleavage [GO:1901310]; positive regulation of triglyceride transport [GO:1905885]; regulation of cholesterol biosynthetic process [GO:0045540]; very-low-density lipoprotein particle assembly [GO:0034379] GO:0003841; GO:0005789; GO:0006656; GO:0016020; GO:0016746; GO:0030258; GO:0034378; GO:0034379; GO:0036150; GO:0036151; GO:0036152; GO:0036335; GO:0045540; GO:0045797; GO:0047144; GO:0047184; GO:0050728; GO:0071617; GO:0090158; GO:0106262; GO:0106263; GO:1901310; GO:1903573; GO:1905885 30330 XR_006394892.1 35 32 24 3 91 NA NA NA NA NA NA 30331 XM_029341565.2 1103 723 659 1011 1289 Q9P107 3.61e-98 GEM-interacting protein (GMIP) Homo sapiens (Human) activation of GTPase activity [GO:0090630]; intracellular signal transduction [GO:0035556]; negative regulation of GTPase activity [GO:0034260]; regulation of small GTPase mediated signal transduction [GO:0051056] GO:0005096; GO:0005654; GO:0005829; GO:0005886; GO:0034260; GO:0035556; GO:0046872; GO:0051056; GO:0090630 30332 XR_006392955.1 41 2 25 5 151 NA NA NA NA NA NA 30333 XM_044308219.1 283 108 192 162 68 Q3SZZ0 2.52e-112 Ribosome biogenesis protein BRX1 homolog (Brix domain-containing protein 2) Bos taurus (Bovine) ribosomal large subunit assembly [GO:0000027]; rRNA processing [GO:0006364] GO:0000027; GO:0003723; GO:0005694; GO:0005730; GO:0006364; GO:0019843 30334 XM_044319652.1 10 365 0 0 135 NA NA NA NA NA NA 30335 XM_044312458.1 0 0 5 1 8 NA NA NA NA NA NA 30336 XM_044323415.1 24 16 38 7 178 NA NA NA NA NA NA 30337 XR_006395440.1 9 1 2 13 54 NA NA NA NA NA NA 30338 XM_044312600.1 49 24 14 19 5 NA NA NA NA NA NA 30339 XM_029351146.2 151 113 67 351 188 NA NA NA NA NA NA 30340 XM_044317356.1 127 35 32 70 150 NA NA NA NA NA NA 30341 XM_044318158.1 119 10 43 26 70 NA NA NA NA NA NA 30342 XM_029358545.2 385 211 227 221 299 A4IH75 7.47e-102 Autophagy-related protein 101 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) autophagy [GO:0006914] GO:0000407; GO:0006914 30343 XM_044308398.1 21 10 18 8 3 Q2TBA3 3.39e-73 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog (EC 3.4.22.-) (Paracaspase) Mus musculus (Mouse) activation of NF-kappaB-inducing kinase activity [GO:0007250]; B cell activation [GO:0042113]; B-1 B cell differentiation [GO:0001923]; cellular response to lipopolysaccharide [GO:0071222]; innate immune response [GO:0045087]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; nuclear export [GO:0051168]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T-helper 17 cell differentiation [GO:2000321]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of apoptotic process [GO:0042981]; regulation of T cell receptor signaling pathway [GO:0050856]; response to fungus [GO:0009620]; T cell proliferation [GO:0042098]; T cell receptor signaling pathway [GO:0050852] GO:0001650; GO:0001923; GO:0002020; GO:0002096; GO:0002726; GO:0004175; GO:0004197; GO:0004842; GO:0005634; GO:0005737; GO:0005829; GO:0006508; GO:0007250; GO:0008233; GO:0009620; GO:0019209; GO:0031663; GO:0032449; GO:0032731; GO:0032743; GO:0032991; GO:0036094; GO:0042098; GO:0042113; GO:0042802; GO:0042981; GO:0043280; GO:0043621; GO:0045087; GO:0048471; GO:0050852; GO:0050856; GO:0050870; GO:0051092; GO:0051168; GO:0051603; GO:0071222; GO:2000321 30344 XR_006396887.1 58 115 95 88 150 NA NA NA NA NA NA 30345 XM_044323749.1 69 49 9 58 10 NA NA NA NA NA NA 30346 XR_006393259.1 248 158 227 265 436 NA NA NA NA NA NA 30347 XM_029352590.2 2 0 0 0 8 NA NA NA NA NA NA 30348 XM_044322513.1 466 383 192 319 134 NA NA NA NA NA NA 30349 XM_044315291.1 0 0 6 17 2 NA NA NA NA NA NA 30350 XM_044311425.1 5 0 3 4 114 NA NA NA NA NA NA 30351 XM_029336256.2 341 191 214 236 218 D4A7U2 6.51e-89 Calcium-responsive transcription factor (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein) (Calcium-response factor) (CaRF) Rattus norvegicus (Rat) cellular response to calcium ion [GO:0071277]; cellular response to potassium ion [GO:0035865]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to calcium ion [GO:0061400]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0001228; GO:0001652; GO:0003677; GO:0003700; GO:0005634; GO:0006357; GO:0035865; GO:0045944; GO:0051090; GO:0061400; GO:0071277 30352 XM_044311151.1 0 4 7 0 3 NA NA NA NA NA NA 30353 XM_044322792.1 7 0 9 13 0 NA NA NA NA NA NA 30354 XM_029343215.2 4014 4046 3726 2740 1937 NA NA NA NA NA NA 30355 XM_029331410.2 15 12 65 94 103 Q6IR42 2.63e-32 Zinc finger CW-type PWWP domain protein 1 Mus musculus (Mouse) cell differentiation [GO:0030154]; homologous chromosome pairing at meiosis [GO:0007129]; meiosis I [GO:0007127]; positive regulation of DNA recombination [GO:0045911]; positive regulation of double-strand break repair [GO:2000781]; spermatogenesis [GO:0007283] GO:0001741; GO:0005634; GO:0007127; GO:0007129; GO:0007283; GO:0008270; GO:0008327; GO:0030154; GO:0035064; GO:0045911; GO:0140566; GO:2000781 30356 XR_006392170.1 0 3 0 6 0 NA NA NA NA NA NA 30357 XR_006397822.1 39 0 22 9 29 NA NA NA NA NA NA 30358 XM_029346592.2 403 408 442 318 525 Q9CXE6 2.56e-85 DNA repair protein XRCC3 (X-ray repair cross-complementing protein 3) Mus musculus (Mouse) DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via synthesis-dependent strand annealing [GO:0045003]; interstrand cross-link repair [GO:0036297]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; regulation of centrosome duplication [GO:0010824]; resolution of mitotic recombination intermediates [GO:0071140]; response to organic substance [GO:0010033]; t-circle formation [GO:0090656]; telomere maintenance via recombination [GO:0000722]; telomere maintenance via telomere trimming [GO:0090737] GO:0000400; GO:0000722; GO:0000724; GO:0005524; GO:0005634; GO:0005654; GO:0005657; GO:0005737; GO:0005739; GO:0005759; GO:0005829; GO:0006281; GO:0008821; GO:0010033; GO:0010824; GO:0033065; GO:0036297; GO:0045003; GO:0048471; GO:0071140; GO:0090267; GO:0090656; GO:0090737; GO:0140664 30359 XR_003824666.2 0 19 22 9 3 NA NA NA NA NA NA 30360 XR_006392904.1 41 2 25 5 151 NA NA NA NA NA NA 30361 XM_029336319.2 0 52 0 0 0 NA NA NA NA NA NA 30362 XM_044309115.1 21 30 4 0 48 NA NA NA NA NA NA 30363 XM_029341159.2 29 0 2 13 0 NA NA NA NA NA NA 30364 XM_029357006.2 1212 636 478 652 1312 Q86W54 1.68e-31 Spermatogenesis-associated protein 24 (Testis protein T6441 homolog) Homo sapiens (Human) cell differentiation [GO:0030154]; spermatogenesis [GO:0007283] GO:0001673; GO:0003677; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0007283; GO:0030154; GO:0042802 30365 XM_044311446.1 367 398 141 378 211 O34363 1.17e-25 Putative L-amino-acid oxidase YobN (EC 1.4.3.2) Bacillus subtilis (strain 168) amino acid catabolic process [GO:0009063] GO:0001716; GO:0009063; GO:0016491; GO:0046592 30366 XM_029348024.2 861 569 570 917 962 B3S3D5 6.77e-42 DDRGK domain-containing protein 1 Trichoplax adhaerens (Trichoplax reptans) NA NA 30367 XM_044318214.1 456 49 38 192 80 NA NA NA NA NA NA 30368 XM_044316382.1 285 377 105 91 467 NA NA NA NA NA NA 30369 XM_044308450.1 743 2374 1580 2051 1319 NA NA NA NA NA NA 30370 XM_029339070.2 1054 1862 1012 1161 1467 Q6TEK8 3.49e-38 Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1-like protein 1) (EC 1.17.4.4) Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) vitamin K metabolic process [GO:0042373] GO:0005789; GO:0042373; GO:0047057; GO:0048038 30371 XM_044317495.1 10 1 8 0 3 NA NA NA NA NA NA 30372 XM_029334766.2 444 122 156 347 721 Q12996 0 Cleavage stimulation factor subunit 3 (CF-1 77 kDa subunit) (Cleavage stimulation factor 77 kDa subunit) (CSTF 77 kDa subunit) (CstF-77) Homo sapiens (Human) mRNA cleavage [GO:0006379]; mRNA polyadenylation [GO:0006378]; RNA 3'-end processing [GO:0031123] GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0006378; GO:0006379; GO:0031123 30373 XM_044315653.1 28 0 0 6 12 NA NA NA NA NA NA 30374 XM_029344895.2 0 0 21 0 0 NA NA NA NA NA NA 30375 XM_044323891.1 1699 158 181 421 244 A0A386CAB9 4.22e-22 NACHT, LRR and PYD domains-containing protein 1 homolog (EC 3.4.-.-) [Cleaved into: NACHT, LRR and PYD domains-containing protein 1, C-terminus (NLRP1-CT); NACHT, LRR and PYD domains-containing protein 1, N-terminus (NLRP1-NT)] Danio rerio (Zebrafish) (Brachydanio rerio) inflammatory response [GO:0006954]; innate immune response [GO:0045087]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; programmed cell death [GO:0012501]; proteolysis [GO:0006508]; regulation of apoptotic process [GO:0042981] GO:0002221; GO:0005524; GO:0005737; GO:0006508; GO:0006954; GO:0008233; GO:0012501; GO:0032731; GO:0042981; GO:0045087; GO:0050729; GO:0072558 30376 XR_006397070.1 61 53 30 26 19 Q5F477 1.75e-53 Lipid droplet-associated hydrolase (EC 3.1.1.-) (Lipid droplet-associated serine hydrolase) Gallus gallus (Chicken) lipid storage [GO:0019915] GO:0004771; GO:0005783; GO:0005811; GO:0019915 30377 XR_006396036.1 0 0 0 6 1 NA NA NA NA NA NA 30378 XM_029345464.2 0 0 0 211 0 Q8N2E2 1.4e-39 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 30379 XM_029345464.2 0 0 0 211 0 Q8N2E2 8.51e-38 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 30380 XM_029345464.2 0 0 0 211 0 Q8N2E2 1.51e-36 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 30381 XM_029345464.2 0 0 0 211 0 Q8N2E2 4.76e-35 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 30382 XM_029345464.2 0 0 0 211 0 Q8N2E2 5.64e-32 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 30383 XM_029345464.2 0 0 0 211 0 Q8N2E2 4.17e-25 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 30384 XM_044328326.1 1618 1242 1054 1627 1887 NA NA NA NA NA NA 30385 XR_003823275.1 2 7 2 9 4 NA NA NA NA NA NA 30386 XM_044325631.1 13 7 4 2 7 NA NA NA NA NA NA 30387 XM_029327335.2 2138 2649 1591 2994 2822 Q7YQK9 4.47e-50 Tetraspanin-7 (Tspan-7) (Transmembrane 4 superfamily member 2) (CD antigen CD231) Pongo pygmaeus (Bornean orangutan) NA GO:0016020 30388 XM_029330536.2 126 185 102 330 135 P21575 0 Dynamin-1 (EC 3.6.5.5) (B-dynamin) (D100) (Dynamin, brain) Rattus norvegicus (Rat) endocytosis [GO:0006897]; endosome organization [GO:0007032]; G protein-coupled receptor internalization [GO:0002031]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; positive regulation of synaptic vesicle recycling [GO:1903423]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of synaptic vesicle endocytosis [GO:1900242]; response to amyloid-beta [GO:1904645]; synaptic vesicle budding from presynaptic endocytic zone membrane [GO:0016185]; synaptic vesicle endocytosis [GO:0048488]; toxin transport [GO:1901998] GO:0001917; GO:0002031; GO:0003924; GO:0005525; GO:0005737; GO:0005794; GO:0005874; GO:0005886; GO:0006897; GO:0006898; GO:0007032; GO:0008017; GO:0008021; GO:0008022; GO:0016020; GO:0016185; GO:0017124; GO:0019901; GO:0030117; GO:0031623; GO:0031749; GO:0032991; GO:0042802; GO:0043196; GO:0044877; GO:0045202; GO:0048488; GO:0050804; GO:0050998; GO:0098684; GO:0098793; GO:0098835; GO:0098978; GO:0120283; GO:1900242; GO:1900244; GO:1901998; GO:1903423; GO:1904645 30389 XM_029354275.2 3686 2595 1319 1659 593 P56376 1.67e-32 Acylphosphatase-1 (EC 3.6.1.7) (Acylphosphatase, organ-common type isozyme) (Acylphosphate phosphohydrolase 1) Mus musculus (Mouse) NA GO:0003998 30390 XM_029348347.2 1591 701 698 2475 818 G3MWR8 0 [F-actin]-monooxygenase MICAL3 (EC 1.14.13.225) (Molecule interacting with CasL protein 3) (MICAL-3) Bos taurus (Bovine) actin filament depolymerization [GO:0030042]; cytoskeleton organization [GO:0007010]; exocytosis [GO:0006887] GO:0003779; GO:0005634; GO:0005819; GO:0005938; GO:0006887; GO:0007010; GO:0016709; GO:0030042; GO:0030496; GO:0042995; GO:0046872; GO:0071949 30391 XM_029348347.2 1591 701 698 2475 818 G3MWR8 1.85e-29 [F-actin]-monooxygenase MICAL3 (EC 1.14.13.225) (Molecule interacting with CasL protein 3) (MICAL-3) Bos taurus (Bovine) actin filament depolymerization [GO:0030042]; cytoskeleton organization [GO:0007010]; exocytosis [GO:0006887] GO:0003779; GO:0005634; GO:0005819; GO:0005938; GO:0006887; GO:0007010; GO:0016709; GO:0030042; GO:0030496; GO:0042995; GO:0046872; GO:0071949 30392 XM_044326045.1 25 1 14 0 12 Q09575 5.75e-37 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 30393 XM_029339936.2 580 370 179 363 297 Q5F4A1 2.13e-71 G2/M phase-specific E3 ubiquitin-protein ligase (EC 2.3.2.26) (G2/M phase-specific HECT-type E3 ubiquitin transferase) Gallus gallus (Chicken) apoptotic process [GO:0006915] GO:0004842; GO:0005634; GO:0005730; GO:0005737; GO:0006915; GO:0046872 30394 XR_006392398.1 0 6 18 0 31 NA NA NA NA NA NA 30395 XM_044320155.1 8 13 164 12 26 NA NA NA NA NA NA 30396 XM_044309164.1 151 305 356 378 859 NA NA NA NA NA NA 30397 XR_003824171.2 861 1524 698 1541 1452 NA NA NA NA NA NA 30398 XM_044327779.1 16 54 75 15 168 NA NA NA NA NA NA 30399 XR_006397823.1 180 82 86 94 164 NA NA NA NA NA NA 30400 XM_044327407.1 805 942 460 1667 1511 Q9UBF8 0 Phosphatidylinositol 4-kinase beta (PI4K-beta) (PI4Kbeta) (PtdIns 4-kinase beta) (EC 2.7.1.67) (NPIK) (PI4K92) (PI4KIII) Homo sapiens (Human) lysosome organization [GO:0007040]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol phosphate biosynthetic process [GO:0046854]; phosphatidylinositol-mediated signaling [GO:0048015]; phosphorylation [GO:0016310]; receptor-mediated endocytosis [GO:0006898]; signal transduction [GO:0007165] GO:0000139; GO:0004430; GO:0005524; GO:0005737; GO:0005741; GO:0005768; GO:0005794; GO:0005829; GO:0006661; GO:0006898; GO:0007040; GO:0007165; GO:0016020; GO:0016310; GO:0030867; GO:0046854; GO:0048015; GO:0048471; GO:0052742; GO:0071889 30401 XM_044309616.1 0 4 7 2 4 NA NA NA NA NA NA 30402 XM_044317684.1 106 0 96 25 0 NA NA NA NA NA NA 30403 XM_044310991.1 38 0 2 0 2 NA NA NA NA NA NA 30404 XM_044321090.1 70 0 29 314 145 Q805E5 3.01e-80 Carbohydrate sulfotransferase 14 (EC 2.8.2.-) (Dermatan 4-sulfotransferase 1) (D4ST-1) (zD4ST-1) Danio rerio (Zebrafish) (Brachydanio rerio) carbohydrate biosynthetic process [GO:0016051]; dermatan sulfate proteoglycan metabolic process [GO:0050655] GO:0000139; GO:0001537; GO:0008146; GO:0016051; GO:0050655 30405 XM_044308213.1 15 0 37 0 0 Q9Z173 7.19e-75 Adhesion G protein-coupled receptor L3 (Calcium-independent alpha-latrotoxin receptor 3) (CIRL-3) (Latrophilin-3) Rattus norvegicus (Rat) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; brain development [GO:0007420]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; locomotion involved in locomotory behavior [GO:0031987]; maintenance of postsynaptic specialization structure [GO:0098880]; neuron migration [GO:0001764]; positive regulation of synapse assembly [GO:0051965]; response to cocaine [GO:0042220]; synapse assembly [GO:0007416]; synapse organization [GO:0050808] GO:0001764; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007166; GO:0007189; GO:0007416; GO:0007420; GO:0030246; GO:0030424; GO:0031987; GO:0042220; GO:0045211; GO:0050808; GO:0051965; GO:0098685; GO:0098742; GO:0098880; GO:0098978 30406 XM_044327581.1 50 94 23 43 0 NA NA NA NA NA NA 30407 XM_029331420.2 16 0 16 0 77 NA NA NA NA NA NA 30408 XM_029341650.2 8 9 21 8 60 A7MCS3 2.37e-34 UPF0764 protein C16orf89 homolog Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005576; GO:0005829; GO:0016020 30409 XM_044320842.1 127 107 59 238 128 B8V7Q1 0 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 30410 XM_044320842.1 127 107 59 238 128 B8V7Q1 0 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 30411 XM_044320842.1 127 107 59 238 128 B8V7Q1 1.19e-30 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 30412 XM_044320842.1 127 107 59 238 128 B8V7Q1 1.59e-29 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 30413 XM_044320842.1 127 107 59 238 128 B8V7Q1 1.59e-29 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 30414 XM_044320842.1 127 107 59 238 128 B8V7Q1 7.93e-29 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 30415 XM_044320842.1 127 107 59 238 128 B8V7Q1 1.08e-21 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 30416 XM_044320842.1 127 107 59 238 128 B8V7Q1 2.6e-21 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 30417 XM_044320842.1 127 107 59 238 128 B8V7Q1 9.18e-21 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 30418 XM_044314285.1 14 4 9 42 21 Q3UQ28 9.3e-32 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 30419 XM_044314285.1 14 4 9 42 21 Q3UQ28 8.19e-29 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 30420 XM_029330647.2 662 166 137 295 378 Q32KH5 0 N-acetylgalactosamine-6-sulfatase (EC 3.1.6.4) (Chondroitinsulfatase) (Chondroitinase) (Galactose-6-sulfate sulfatase) (N-acetylgalactosamine-6-sulfate sulfatase) (GalNAc6S sulfatase) Canis lupus familiaris (Dog) (Canis familiaris) NA GO:0004065; GO:0005764; GO:0043890; GO:0046872 30421 XM_029343995.2 1145 1010 674 977 892 NA NA NA NA NA NA 30422 XM_044315900.1 0 0 11 0 2 Q09575 4.55e-25 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 30423 XM_029338615.2 531 347 324 371 673 NA NA NA NA NA NA 30424 XR_003823218.2 24 17 11 18 53 NA NA NA NA NA NA 30425 XM_029353386.2 29 3 0 3 34 NA NA NA NA NA NA 30426 XM_029325020.2 112 121 0 292 140 NA NA NA NA NA NA 30427 XM_044327399.1 49 13 14 4 45 Q9USQ7 1.95e-106 Diphthine--ammonia ligase (EC 6.3.1.14) (Diphthamide synthase) (Diphthamide synthetase) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) meiotic cell cycle [GO:0051321]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]; regulation of cytoplasmic translation [GO:2000765] GO:0005524; GO:0005634; GO:0005829; GO:0017178; GO:0017183; GO:0051321; GO:2000765 30428 XM_044329235.1 326 254 114 185 241 Q2T9S3 1.49e-130 DNA-directed RNA polymerase III subunit RPC6 (RNA polymerase III subunit C6) (DNA-directed RNA polymerase III subunit F) Bos taurus (Bovine) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-beta production [GO:0032728]; transcription by RNA polymerase III [GO:0006383] GO:0003690; GO:0005666; GO:0006383; GO:0032728; GO:0045087; GO:0045089; GO:0051607 30429 XM_029341047.2 322 138 216 152 281 Q8C190 1.16e-47 VPS9 domain-containing protein 1 (5-day ovary-specific transcript 1 protein) Mus musculus (Mouse) vesicle-mediated transport [GO:0016192] GO:0005085; GO:0005829; GO:0016192; GO:0030139; GO:0031267; GO:0042802 30430 XM_029341047.2 322 138 216 152 281 Q8C190 6.18e-22 VPS9 domain-containing protein 1 (5-day ovary-specific transcript 1 protein) Mus musculus (Mouse) vesicle-mediated transport [GO:0016192] GO:0005085; GO:0005829; GO:0016192; GO:0030139; GO:0031267; GO:0042802 30431 XM_029328623.2 1022 1225 814 887 1697 NA NA NA NA NA NA 30432 XR_003825277.2 49 1 54 13 214 NA NA NA NA NA NA 30433 XM_044313667.1 43 0 6 15 24 Q7RTR2 7.7e-28 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30434 XM_044323546.1 12 0 44 5 31 NA NA NA NA NA NA 30435 XM_044306862.1 697 161 434 529 372 B3EWY9 0 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 30436 XM_044328676.1 434 141 92 94 224 NA NA NA NA NA NA 30437 XM_029347884.2 24812 8395 5503 6607 4336 Q13887 3.89e-52 Krueppel-like factor 5 (Basic transcription element-binding protein 2) (BTE-binding protein 2) (Colon krueppel-like factor) (GC-box-binding protein 2) (Intestinal-enriched krueppel-like factor) (Transcription factor BTEB2) Homo sapiens (Human) angiogenesis [GO:0001525]; cell-cell signaling via exosome [GO:0099156]; cellular response to leukemia inhibitory factor [GO:1990830]; intestinal epithelial cell development [GO:0060576]; microvillus assembly [GO:0030033]; myotube differentiation involved in skeletal muscle regeneration [GO:0014908]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription by transcription factor localization [GO:0061586]; regulation of microvillus assembly [GO:0032534]; regulation of transcription by RNA polymerase II [GO:0006357]; satellite cell activation involved in skeletal muscle regeneration [GO:0014901]; skeletal muscle satellite cell differentiation [GO:0014816] GO:0000122; GO:0000785; GO:0000978; GO:0000981; GO:0001228; GO:0001525; GO:0005654; GO:0005667; GO:0005794; GO:0006357; GO:0014816; GO:0014901; GO:0014908; GO:0030033; GO:0032534; GO:0043231; GO:0043426; GO:0045600; GO:0045944; GO:0046872; GO:0060576; GO:0061586; GO:0099156; GO:1902895; GO:1990830; GO:1990837 30438 XM_029329411.2 2467 2809 1665 1901 1474 Q2KMM2 1.63e-67 Trafficking protein particle complex subunit 1 Rattus norvegicus (Rat) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888] GO:0005783; GO:0005794; GO:0006888; GO:0030008 30439 XM_044320585.1 588 0 256 493 0 NA NA NA NA NA NA 30440 XM_029341813.2 325 584 0 357 247 A2AJ88 0 Patatin-like phospholipase domain-containing protein 7 (EC 3.1.1.-) (EC 3.1.1.5) (Neuropathy target esterase-related esterase) (NRE) (NTE-related esterase) Mus musculus (Mouse) phosphatidylcholine catabolic process [GO:0034638] GO:0004622; GO:0005783; GO:0005789; GO:0005811; GO:0034638; GO:0102545 30441 XM_029333005.2 78 64 30 65 77 NA NA NA NA NA NA 30442 XM_044327534.1 13486 16294 8578 12840 8137 Q9GLW7 1.99e-62 Peroxiredoxin-5, mitochondrial (EC 1.11.1.24) (Peroxiredoxin V) (Prx-V) (Thioredoxin peroxidase) (Thioredoxin-dependent peroxiredoxin 5) Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops) cellular response to oxidative stress [GO:0034599] GO:0005739; GO:0005782; GO:0008379; GO:0034599 30443 XM_029340876.2 6 1 3 4 21 NA NA NA NA NA NA 30444 XR_006398054.1 68 0 0 0 0 NA NA NA NA NA NA 30445 XR_003824259.2 31 44 82 89 113 NA NA NA NA NA NA 30446 XM_044309809.1 0 0 0 14 0 P49013 8.56e-55 Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374 30447 XM_044309809.1 0 0 0 14 0 P49013 1.55e-53 Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374 30448 XM_044309809.1 0 0 0 14 0 P49013 4.8e-49 Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374 30449 XM_044309809.1 0 0 0 14 0 P49013 7.75e-39 Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374 30450 XM_044309809.1 0 0 0 14 0 P49013 3.58e-37 Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374 30451 XM_044309809.1 0 0 0 14 0 P49013 5.16e-27 Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374 30452 XR_006394412.1 80 54 53 105 159 NA NA NA NA NA NA 30453 XM_044319800.1 0 0 0 13 4 Q09694 1.1e-84 Saccharopine dehydrogenase [NAD(+), L-lysine-forming] (SDH) (EC 1.5.1.7) (Lysine--2-oxoglutarate reductase) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) lysine biosynthetic process [GO:0009085]; lysine biosynthetic process via aminoadipic acid [GO:0019878] GO:0004753; GO:0004754; GO:0005737; GO:0009085; GO:0019878 30454 XM_044325296.1 264 77 140 239 214 NA NA NA NA NA NA 30455 XR_006395294.1 605 753 699 678 655 NA NA NA NA NA NA 30456 XM_044308524.1 25 5 50 15 83 NA NA NA NA NA NA 30457 XM_029350241.2 358 165 113 179 201 Q9H3H5 7.04e-155 UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (EC 2.7.8.15) (GlcNAc-1-P transferase) (G1PT) (GPT) (N-acetylglucosamine-1-phosphate transferase) Homo sapiens (Human) dolichol metabolic process [GO:0019348]; dolichol-linked oligosaccharide biosynthetic process [GO:0006488]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine metabolic process [GO:0006047] GO:0003975; GO:0003976; GO:0005789; GO:0006047; GO:0006487; GO:0006488; GO:0016020; GO:0016757; GO:0019348; GO:0042802; GO:0043231; GO:0046872 30458 XM_029339248.2 46 0 0 0 0 NA NA NA NA NA NA 30459 XM_044308644.1 222 230 265 241 231 NA NA NA NA NA NA 30460 XM_044317959.1 12 0 47 13 4 NA NA NA NA NA NA 30461 XM_044314974.1 5 4 36 1 7 NA NA NA NA NA NA 30462 XM_029354557.2 606 387 457 570 762 Q5ZIH0 0 Integrator complex subunit 11 (Int11) (EC 3.1.27.-) (Cleavage and polyadenylation-specific factor 3-like protein) (CPSF3-like protein) Gallus gallus (Chicken) snRNA processing [GO:0016180] GO:0005634; GO:0016180; GO:0016787; GO:0032039 30463 XM_044319111.1 0 5 2 15 0 NA NA NA NA NA NA 30464 XM_029348841.2 0 0 0 31 0 Q9FWW9 2.75e-54 Flavin-containing monooxygenase FMO GS-OX-like 2 (EC 1.8.-.-) (Flavin-monooxygenase glucosinolate S-oxygenase-like 2) Arabidopsis thaliana (Mouse-ear cress) defense response to fungus [GO:0050832] GO:0004499; GO:0050660; GO:0050661; GO:0050832 30465 XR_006392858.1 58 61 33 119 188 NA NA NA NA NA NA 30466 XR_003822907.2 7 13 0 0 9 NA NA NA NA NA NA 30467 XM_044306757.1 929 700 401 626 623 P42696 5.04e-44 RNA-binding protein 34 (RNA-binding motif protein 34) Homo sapiens (Human) NA GO:0003723; GO:0005654; GO:0005694; GO:0005730 30468 XM_029340503.2 68 44 118 137 43 Q5XIN7 8.36e-173 Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGnT1) (EC 2.4.1.-) Rattus norvegicus (Rat) O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493] GO:0000139; GO:0006493; GO:0008375; GO:0016020; GO:0016266; GO:0030145; GO:0047223 30469 XM_044323185.1 529 324 293 490 422 A2AR02 3.33e-69 Peptidyl-prolyl cis-trans isomerase G (PPIase G) (Peptidyl-prolyl isomerase G) (EC 5.2.1.8) (Cyclophilin G) (Rotamase G) Mus musculus (Mouse) protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413] GO:0000413; GO:0003755; GO:0005634; GO:0005737; GO:0005829; GO:0006457; GO:0016018; GO:0016363; GO:0016607; GO:0043231 30470 XM_044325577.1 20 2 3 4 22 NA NA NA NA NA NA 30471 XM_029349646.2 470 48 114 172 225 O57321 4.31e-113 Excitatory amino acid transporter 1 (SEAAT1) (Sodium-dependent glutamate/aspartate transporter) (GLAST) Ambystoma tigrinum (Eastern tiger salamander) chloride transmembrane transport [GO:1902476]; D-aspartate import across plasma membrane [GO:0070779]; L-aspartate import across plasma membrane [GO:0140009]; L-glutamate import across plasma membrane [GO:0098712]; potassium ion transmembrane transport [GO:0071805] GO:0005314; GO:0005886; GO:0015501; GO:0046872; GO:0070779; GO:0071805; GO:0098712; GO:0140009; GO:1902476 30472 XM_044313281.1 191 383 118 405 355 NA NA NA NA NA NA 30473 XM_044317964.1 0 0 19 12 0 NA NA NA NA NA NA 30474 XR_003825125.2 164 118 176 136 142 NA NA NA NA NA NA 30475 XM_044316637.1 143 1688 76 126 85 NA NA NA NA NA NA 30476 XM_044315289.1 30 2 60 95 32 NA NA NA NA NA NA 30477 XM_029344429.2 1360 1506 1004 1859 1798 A2AB59 1.49e-75 Rho GTPase-activating protein 27 (CIN85-associated multi-domain-containing Rho GTPase-activating protein 1) (Rho-type GTPase-activating protein 27) Mus musculus (Mouse) positive regulation of GTPase activity [GO:0043547]; receptor-mediated endocytosis [GO:0006898]; regulation of GTPase activity [GO:0043087]; signal transduction [GO:0007165] GO:0005096; GO:0005737; GO:0005768; GO:0006898; GO:0007165; GO:0016020; GO:0017124; GO:0043087; GO:0043547 30478 XM_029337112.2 0 0 596 387 2161 A2RV80 6.6e-70 GRAM domain-containing protein 4 Xenopus laevis (African clawed frog) apoptotic process [GO:0006915] GO:0005789; GO:0006915; GO:0031966 30479 XM_029339797.2 0 0 0 7 0 NA NA NA NA NA NA 30480 XM_029356301.2 1935 1283 714 1313 2121 Q32LQ0 0 Glutamyl aminopeptidase (EAP) (EC 3.4.11.7) (Aminopeptidase A) (AP-A) (CD antigen CD249) Bos taurus (Bovine) cell migration [GO:0016477]; cell population proliferation [GO:0008283]; proteolysis [GO:0006508]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081] GO:0003081; GO:0004177; GO:0005886; GO:0006508; GO:0008270; GO:0008283; GO:0016477; GO:0070006 30481 XM_044306766.1 507 0 321 172 523 Q90Y54 0 Protein jagged-1b (Jagged1b) (Jagged3) Danio rerio (Zebrafish) (Brachydanio rerio) auditory receptor cell development [GO:0060117]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; cranial skeletal system development [GO:1904888]; dorsal/ventral pattern formation [GO:0009953]; exocrine pancreas development [GO:0031017]; face morphogenesis [GO:0060325]; fin regeneration [GO:0031101]; inner ear morphogenesis [GO:0042472]; intrahepatic bile duct development [GO:0035622]; liver development [GO:0001889]; Notch signaling pathway [GO:0007219]; otolith morphogenesis [GO:0032474]; pancreas development [GO:0031016]; semicircular canal development [GO:0060872]; semicircular canal morphogenesis [GO:0048752]; thyroid gland development [GO:0030878] GO:0001889; GO:0005112; GO:0005509; GO:0005886; GO:0007219; GO:0009953; GO:0030878; GO:0031016; GO:0031017; GO:0031101; GO:0032474; GO:0035622; GO:0042472; GO:0048752; GO:0060117; GO:0060325; GO:0060351; GO:0060872; GO:1904888 30482 XM_044306766.1 507 0 321 172 523 Q90Y54 4.12e-163 Protein jagged-1b (Jagged1b) (Jagged3) Danio rerio (Zebrafish) (Brachydanio rerio) auditory receptor cell development [GO:0060117]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; cranial skeletal system development [GO:1904888]; dorsal/ventral pattern formation [GO:0009953]; exocrine pancreas development [GO:0031017]; face morphogenesis [GO:0060325]; fin regeneration [GO:0031101]; inner ear morphogenesis [GO:0042472]; intrahepatic bile duct development [GO:0035622]; liver development [GO:0001889]; Notch signaling pathway [GO:0007219]; otolith morphogenesis [GO:0032474]; pancreas development [GO:0031016]; semicircular canal development [GO:0060872]; semicircular canal morphogenesis [GO:0048752]; thyroid gland development [GO:0030878] GO:0001889; GO:0005112; GO:0005509; GO:0005886; GO:0007219; GO:0009953; GO:0030878; GO:0031016; GO:0031017; GO:0031101; GO:0032474; GO:0035622; GO:0042472; GO:0048752; GO:0060117; GO:0060325; GO:0060351; GO:0060872; GO:1904888 30483 XM_044306766.1 507 0 321 172 523 Q90Y54 3.01e-24 Protein jagged-1b (Jagged1b) (Jagged3) Danio rerio (Zebrafish) (Brachydanio rerio) auditory receptor cell development [GO:0060117]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; cranial skeletal system development [GO:1904888]; dorsal/ventral pattern formation [GO:0009953]; exocrine pancreas development [GO:0031017]; face morphogenesis [GO:0060325]; fin regeneration [GO:0031101]; inner ear morphogenesis [GO:0042472]; intrahepatic bile duct development [GO:0035622]; liver development [GO:0001889]; Notch signaling pathway [GO:0007219]; otolith morphogenesis [GO:0032474]; pancreas development [GO:0031016]; semicircular canal development [GO:0060872]; semicircular canal morphogenesis [GO:0048752]; thyroid gland development [GO:0030878] GO:0001889; GO:0005112; GO:0005509; GO:0005886; GO:0007219; GO:0009953; GO:0030878; GO:0031016; GO:0031017; GO:0031101; GO:0032474; GO:0035622; GO:0042472; GO:0048752; GO:0060117; GO:0060325; GO:0060351; GO:0060872; GO:1904888 30484 XM_029323636.2 17138 23879 19232 17040 8010 Q8QGH2 1.12e-38 Small ubiquitin-related modifier 1 (SUMO-1) Gallus gallus (Chicken) cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; protein sumoylation [GO:0016925] GO:0005634; GO:0005737; GO:0005886; GO:0008134; GO:0016605; GO:0016607; GO:0016925; GO:0031386; GO:0031965; GO:0034605; GO:0044389; GO:0071276; GO:0097165 30485 XM_044324121.1 57 5 17 96 0 P07949 7.51e-77 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; axon guidance [GO:0007411]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; lymphocyte migration into lymphoid organs [GO:0097021]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; posterior midgut development [GO:0007497]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006468; GO:0006919; GO:0007156; GO:0007158; GO:0007165; GO:0007169; GO:0007411; GO:0007497; GO:0009410; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0038023; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0097021; GO:0098797; GO:2001241 30486 XM_044326395.1 41 47 82 48 100 Q14683 0 Structural maintenance of chromosomes protein 1A (SMC protein 1A) (SMC-1-alpha) (SMC-1A) (Sb1.8) Homo sapiens (Human) cell division [GO:0051301]; DNA repair [GO:0006281]; establishment of meiotic sister chromatid cohesion [GO:0034089]; establishment of mitotic sister chromatid cohesion [GO:0034087]; meiotic cell cycle [GO:0051321]; mitotic sister chromatid cohesion [GO:0007064]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly [GO:0090307]; response to DNA damage checkpoint signaling [GO:0072423]; response to radiation [GO:0009314]; sister chromatid cohesion [GO:0007062]; somatic stem cell population maintenance [GO:0035019] GO:0000070; GO:0000775; GO:0000776; GO:0000794; GO:0003677; GO:0003682; GO:0003723; GO:0005524; GO:0005634; GO:0005654; GO:0005694; GO:0005829; GO:0006281; GO:0007062; GO:0007064; GO:0008278; GO:0009314; GO:0016363; GO:0016887; GO:0030893; GO:0034087; GO:0034089; GO:0035019; GO:0036033; GO:0046982; GO:0051301; GO:0051321; GO:0072423; GO:0090307; GO:0097431 30487 XR_006394859.1 22 47 0 0 21 NA NA NA NA NA NA 30488 XM_029331364.2 6 11 18 10 2 Q8C811 3.43e-73 Solute carrier family 35 member E2A Mus musculus (Mouse) blastocyst hatching [GO:0001835] GO:0001835; GO:0005794; GO:0015297; GO:0016020 30489 XM_044326978.1 27 8 11 94 19 Q28107 6.51e-25 Coagulation factor V (Activated protein C cofactor) [Cleaved into: Coagulation factor V heavy chain; Coagulation factor V light chain] Bos taurus (Bovine) blood circulation [GO:0008015]; blood coagulation [GO:0007596] GO:0005507; GO:0005576; GO:0007596; GO:0008015; GO:0031091 30490 XM_029342711.2 3703 3457 2599 3156 1384 Q5NC57 1.49e-22 Protein FAM183B Mus musculus (Mouse) NA GO:0005737; GO:0005813; GO:0036064; GO:0097546 30491 XM_044321314.1 289 0 0 118 25 Q13416 4.09e-112 Origin recognition complex subunit 2 Homo sapiens (Human) DNA replication initiation [GO:0006270]; negative regulation of transcription by RNA polymerase II [GO:0000122] GO:0000122; GO:0000781; GO:0000792; GO:0000808; GO:0000939; GO:0003688; GO:0005634; GO:0005654; GO:0005664; GO:0005813; GO:0006270; GO:0016020 30492 XM_044309987.1 8 27 6 38 29 NA NA NA NA NA NA 30493 XR_006391327.1 10 30 3 8 20 NA NA NA NA NA NA 30494 XM_029356261.2 3844 5160 1890 2865 2246 Q9DCT6 5.8e-25 Chromatin complexes subunit BAP18 (BPTF-associated protein of 18 kDa) Mus musculus (Mouse) chromatin organization [GO:0006325] GO:0003677; GO:0005654; GO:0005829; GO:0006325; GO:0016589; GO:0042802; GO:0071339 30495 XM_029340144.2 304 8 63 376 153 O46504 3.91e-169 Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial (PDPr) Bos taurus (Bovine) NA GO:0005759; GO:0016491 30496 XM_029329040.2 628 369 296 327 488 Q6AY85 2.25e-75 UDP-N-acetylglucosamine transferase subunit ALG14 homolog Rattus norvegicus (Rat) dolichol-linked oligosaccharide biosynthetic process [GO:0006488] GO:0006488; GO:0031965; GO:0043541 30497 XR_006397361.1 0 14 87 0 0 NA NA NA NA NA NA 30498 XM_044328891.1 96 52 108 112 109 Q96DB5 6.72e-49 Regulator of microtubule dynamics protein 1 (RMD-1) (hRMD-1) (Protein FAM82B) Homo sapiens (Human) attachment of mitotic spindle microtubules to kinetochore [GO:0051315]; mitotic spindle organization [GO:0007052] GO:0005737; GO:0005876; GO:0007052; GO:0008017; GO:0051315; GO:0097431 30499 XR_006391924.1 2 4 5 8 2 NA NA NA NA NA NA 30500 XM_044322900.1 103 167 46 38 175 Q95SX7 6.98e-26 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 30501 XM_044328480.1 1033 1414 549 1939 1441 Q2KJI2 0 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (Oligosaccharyl transferase subunit STT3A) (STT3-A) (EC 2.4.99.18) Bos taurus (Bovine) co-translational protein modification [GO:0043686]; post-translational protein modification [GO:0043687]; protein N-linked glycosylation via asparagine [GO:0018279] GO:0004579; GO:0018279; GO:0035000; GO:0043686; GO:0043687; GO:0046872 30502 XM_044320588.1 1 48 4 53 16 NA NA NA NA NA NA 30503 XM_029333503.2 39 4 0 10 13 Q63HM2 0 Pecanex-like protein 4 (Hepatitis C virus F protein-binding protein 2) (HCV F protein-binding protein 2) (Pecanex homolog protein 4) Homo sapiens (Human) NA GO:0016020 30504 XR_006395328.1 3 11 5 0 0 NA NA NA NA NA NA 30505 XM_044325686.1 0 7 6 1 0 Q6DIV6 1.42e-42 Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Solute carrier family 32 member 1) (Vesicular GABA transporter) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) beta-alanine transport [GO:0001762]; gamma-aminobutyric acid import [GO:0051939]; gamma-aminobutyric acid transport [GO:0015812]; glycine transport [GO:0015816]; neurotransmitter transport [GO:0006836] GO:0001762; GO:0006836; GO:0008021; GO:0015185; GO:0015187; GO:0015812; GO:0015816; GO:0030659; GO:0042995; GO:0051939; GO:0098793; GO:0140799; GO:0140800 30506 XM_044319466.1 0 0 15 0 5 NA NA NA NA NA NA 30507 XR_006396221.1 90 0 27 7 0 Q80UG8 0 Tubulin monoglutamylase TTLL4 (EC 6.3.2.-) (Protein monoglutamylase TTLL4) (Tubulin--tyrosine ligase-like protein 4) Mus musculus (Mouse) microtubule cytoskeleton organization [GO:0000226]; peptidyl-glutamic acid modification [GO:0018200]; protein polyglutamylation [GO:0018095]; regulation of blastocyst development [GO:0120222] GO:0000226; GO:0005524; GO:0005737; GO:0005874; GO:0005929; GO:0015631; GO:0018095; GO:0018200; GO:0036064; GO:0046872; GO:0070739; GO:0070740; GO:0097731; GO:0120222 30508 XM_044326797.1 57 2 23 73 66 NA NA NA NA NA NA 30509 XM_029338018.2 2279 1687 1229 2820 2089 NA NA NA NA NA NA 30510 XM_029330528.2 1412 714 566 719 719 NA NA NA NA NA NA 30511 XM_029330043.2 2 0 23 5 40 NA NA NA NA NA NA 30512 XM_044322966.1 256 304 163 175 346 Q5E9C0 1.16e-100 Ras suppressor protein 1 (Rsu-1) Bos taurus (Bovine) NA NA 30513 XM_029352974.2 277 99 120 206 174 Q6TCG8 1e-85 Progestin and adipoQ receptor family member 3 (Progestin and adipoQ receptor family member III) (Raf kinase trapping to Golgi) (RKTG) Mus musculus (Mouse) negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron projection development [GO:0010977]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of protein phosphorylation [GO:0001933]; protein localization to Golgi apparatus [GO:0034067]; protein phosphorylation [GO:0006468] GO:0000139; GO:0001933; GO:0005794; GO:0006468; GO:0010977; GO:0033137; GO:0034067; GO:0038023; GO:0043407 30514 XM_029334114.2 22 87 29 0 12 Q60547 2.21e-39 Synaptonemal complex protein 3 (SCP-3) (Meiotic chromosome core protein) (Synaptonemal complex protein COR1) Mesocricetus auratus (Golden hamster) cell division [GO:0051301]; meiotic cell cycle [GO:0051321] GO:0000775; GO:0000800; GO:0003677; GO:0005694; GO:0051301; GO:0051321 30515 XM_029340117.2 191 167 58 197 276 Q75NR7 3.94e-149 ATP-dependent DNA helicase Q4 (EC 3.6.4.12) (DNA helicase, RecQ-like type 4) (RecQ4) (RecQ protein-like 4) Mus musculus (Mouse) DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724]; negative regulation of sister chromatid cohesion [GO:0045875]; pigmentation [GO:0043473]; positive regulation of cell population proliferation [GO:0008284]; sister chromatid cohesion [GO:0007062]; skeletal system development [GO:0001501]; skeletal system morphogenesis [GO:0048705]; telomere maintenance [GO:0000723]; telomeric D-loop disassembly [GO:0061820] GO:0000405; GO:0000723; GO:0000724; GO:0000781; GO:0001501; GO:0005524; GO:0005634; GO:0005654; GO:0005694; GO:0005737; GO:0006260; GO:0006268; GO:0006281; GO:0006310; GO:0007062; GO:0008270; GO:0008284; GO:0009378; GO:0016887; GO:0032357; GO:0032508; GO:0043138; GO:0043473; GO:0045875; GO:0048705; GO:0061820; GO:0061821; GO:1990814 30516 XM_029340117.2 191 167 58 197 276 Q75NR7 7.26e-67 ATP-dependent DNA helicase Q4 (EC 3.6.4.12) (DNA helicase, RecQ-like type 4) (RecQ4) (RecQ protein-like 4) Mus musculus (Mouse) DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724]; negative regulation of sister chromatid cohesion [GO:0045875]; pigmentation [GO:0043473]; positive regulation of cell population proliferation [GO:0008284]; sister chromatid cohesion [GO:0007062]; skeletal system development [GO:0001501]; skeletal system morphogenesis [GO:0048705]; telomere maintenance [GO:0000723]; telomeric D-loop disassembly [GO:0061820] GO:0000405; GO:0000723; GO:0000724; GO:0000781; GO:0001501; GO:0005524; GO:0005634; GO:0005654; GO:0005694; GO:0005737; GO:0006260; GO:0006268; GO:0006281; GO:0006310; GO:0007062; GO:0008270; GO:0008284; GO:0009378; GO:0016887; GO:0032357; GO:0032508; GO:0043138; GO:0043473; GO:0045875; GO:0048705; GO:0061820; GO:0061821; GO:1990814 30517 XR_003825198.2 302 135 123 98 121 NA NA NA NA NA NA 30518 XM_044314244.1 88 39 33 67 111 Q8NB78 0 Lysine-specific histone demethylase 2 (EC 1.14.99.66) (Flavin-containing amine oxidase domain-containing protein 1) (Lysine-specific histone demethylase 1B) Homo sapiens (Human) DNA methylation involved in gamete generation [GO:0043046]; histone H3-K4 demethylation [GO:0034720]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA methylation [GO:0044030]; regulation of gene expression by genomic imprinting [GO:0006349] GO:0000122; GO:0000786; GO:0003682; GO:0005634; GO:0005654; GO:0006349; GO:0008270; GO:0016491; GO:0032452; GO:0034720; GO:0042393; GO:0043046; GO:0044030; GO:0045944; GO:0050660; GO:0071949; GO:0140682 30519 XM_029331888.2 486 329 266 890 1039 A1L1W9 2.88e-54 Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10) Danio rerio (Zebrafish) (Brachydanio rerio) aromatic amino acid transport [GO:0015801]; thyroid hormone transport [GO:0070327] GO:0005302; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0070327 30520 XM_029357011.2 195 66 112 252 181 Q86UD5 1.94e-125 Sodium/hydrogen exchanger 9B2 (Na(+)/H(+) exchanger NHA2) (Na(+)/H(+) exchanger-like domain-containing protein 2) (NHE domain-containing protein 2) (Sodium/hydrogen exchanger-like domain-containing protein 2) (Solute carrier family 9 subfamily B member 2) Homo sapiens (Human) clathrin-dependent endocytosis [GO:0072583]; flagellated sperm motility [GO:0030317]; ion transmembrane transport [GO:0034220]; positive regulation of osteoclast development [GO:2001206]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; sodium ion transport [GO:0006814] GO:0005743; GO:0005886; GO:0006814; GO:0010008; GO:0010348; GO:0015385; GO:0016323; GO:0016324; GO:0030317; GO:0030672; GO:0031966; GO:0034220; GO:0042802; GO:0061178; GO:0072583; GO:0097228; GO:2001206 30521 XM_029343579.2 1738 1671 675 3112 4191 P47862 5.63e-82 Aquaporin-3 (AQP-3) (31.4 kDa water channel protein) (Aquaglyceroporin-3) Rattus norvegicus (Rat) cellular response to hypoxia [GO:0071456]; cellular response to oxygen-glucose deprivation [GO:0090650]; establishment of localization in cell [GO:0051649]; glycerol transmembrane transport [GO:0015793]; odontogenesis [GO:0042476]; polyol transmembrane transport [GO:0015791]; positive regulation of immune system process [GO:0002684]; renal water absorption [GO:0070295]; response to retinoic acid [GO:0032526]; urea transport [GO:0015840]; water transport [GO:0006833] GO:0002684; GO:0005737; GO:0005886; GO:0005911; GO:0006833; GO:0015166; GO:0015204; GO:0015250; GO:0015254; GO:0015791; GO:0015793; GO:0015840; GO:0016323; GO:0032526; GO:0042476; GO:0042802; GO:0051649; GO:0070295; GO:0071456; GO:0090650 30522 XR_006393363.1 36 0 0 16 152 NA NA NA NA NA NA 30523 XM_044320242.1 0 0 19 0 60 P17892 2.44e-50 Pancreatic lipase-related protein 2 (PL-RP2) (Cytotoxic T lymphocyte lipase) (Galactolipase) (EC 3.1.1.26) (Triacylglycerol lipase) (EC 3.1.1.3) Mus musculus (Mouse) cellular defense response [GO:0006968]; galactolipid catabolic process [GO:0019376]; intestinal lipid catabolic process [GO:0044258]; lipid catabolic process [GO:0016042]; phosphatidylcholine catabolic process [GO:0034638]; phospholipid catabolic process [GO:0009395]; phospholipid metabolic process [GO:0006644]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433] GO:0004620; GO:0004806; GO:0005509; GO:0005615; GO:0006644; GO:0006968; GO:0009395; GO:0009617; GO:0016042; GO:0016298; GO:0019376; GO:0019433; GO:0034638; GO:0042589; GO:0043005; GO:0044258; GO:0047372; GO:0047714; GO:0102549 30524 XR_006393826.1 22 0 0 0 0 NA NA NA NA NA NA 30525 XM_029327179.2 57 35 74 102 127 O88871 1.59e-122 Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51) Rattus norvegicus (Rat) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; gamma-aminobutyric acid signaling pathway [GO:0007214]; neuron-glial cell signaling [GO:0150099]; synaptic transmission, GABAergic [GO:0051932] GO:0004888; GO:0004965; GO:0005737; GO:0005886; GO:0007193; GO:0007214; GO:0016020; GO:0030425; GO:0038039; GO:0042734; GO:0043005; GO:0043204; GO:0045211; GO:0046982; GO:0051932; GO:0098978; GO:0098982; GO:0150099; GO:1902710; GO:1902712 30526 XM_044323030.1 146 30 15 60 91 Q9Y238 1.64e-75 Deleted in lung and esophageal cancer protein 1 (Deleted in lung cancer protein 1) (DLC-1) Homo sapiens (Human) cell differentiation [GO:0030154]; defense response to tumor cell [GO:0002357]; negative regulation of cell population proliferation [GO:0008285]; spermatogenesis [GO:0007283] GO:0002357; GO:0005737; GO:0005829; GO:0005929; GO:0007283; GO:0008285; GO:0015631; GO:0030154; GO:0043014; GO:0048487 30527 XM_029336556.2 6 0 0 53 16 Q29496 7.65e-105 Cytochrome P450 3A24 (EC 1.14.14.1) (CYPIIIA24) Ovis aries (Sheep) NA GO:0004497; GO:0005506; GO:0005789; GO:0020037; GO:0070330 30528 XM_029346794.2 18 0 20 2 89 NA NA NA NA NA NA 30529 XM_044309798.1 349 425 118 639 1770 NA NA NA NA NA NA 30530 XM_029357656.2 1503 961 880 1190 852 B7PRF6 1.71e-83 Acireductone dioxygenase (Acireductone dioxygenase (Fe(2+)-requiring)) (ARD') (Fe-ARD) (EC 1.13.11.54) (Acireductone dioxygenase (Ni(2+)-requiring)) (ARD) (Ni-ARD) (EC 1.13.11.53) Ixodes scapularis (Black-legged tick) (Deer tick) L-methionine salvage from methylthioadenosine [GO:0019509]; methionine metabolic process [GO:0006555] GO:0005506; GO:0005634; GO:0005737; GO:0006555; GO:0010308; GO:0010309; GO:0016151; GO:0019509 30531 XM_044318817.1 3 5 0 11 58 NA NA NA NA NA NA 30532 XM_029335717.2 0 24 0 0 0 Q01085 6.73e-63 Nucleolysin TIAR (TIA-1-related protein) Homo sapiens (Human) apoptotic process [GO:0006915]; defense response [GO:0006952]; germ cell development [GO:0007281]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of hippo signaling [GO:0035332]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; positive regulation of stem cell proliferation [GO:2000648]; regulation of transcription by RNA polymerase II [GO:0006357]; stem cell division [GO:0017145]; stem cell proliferation [GO:0072089] GO:0003677; GO:0003723; GO:0003730; GO:0005634; GO:0005654; GO:0005737; GO:0005764; GO:0006357; GO:0006915; GO:0006952; GO:0007281; GO:0008285; GO:0010494; GO:0017145; GO:0035332; GO:0035925; GO:0044194; GO:0072089; GO:0140517; GO:2000637; GO:2000648 30533 XM_044310055.1 10 0 0 25 0 NA NA NA NA NA NA 30534 XM_044325280.1 10 15 54 16 172 NA NA NA NA NA NA 30535 XM_044322166.1 11 3 4 2 1 F4K4C5 5.12e-25 Kinesin-like protein KIN-14S Arabidopsis thaliana (Mouse-ear cress) cytoskeleton-dependent intracellular transport [GO:0030705]; microtubule-based movement [GO:0007018] GO:0003777; GO:0005524; GO:0005871; GO:0005874; GO:0007018; GO:0008017; GO:0008574; GO:0016887; GO:0030705 30536 XM_044323718.1 99 271 92 84 97 Q96AY4 4.1e-111 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30537 XM_044323718.1 99 271 92 84 97 Q96AY4 9.39e-104 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30538 XM_044323718.1 99 271 92 84 97 Q96AY4 1.18e-87 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30539 XM_044323718.1 99 271 92 84 97 Q96AY4 3.92e-82 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30540 XM_044323718.1 99 271 92 84 97 Q96AY4 6.79e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30541 XM_029345978.2 41 31 10 35 37 Q8BSL4 1.98e-76 Heparan sulfate glucosamine 3-O-sulfotransferase 5 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5) (Heparan sulfate 3-O-sulfotransferase 5) Mus musculus (Mouse) heparan sulfate proteoglycan biosynthetic process [GO:0015012]; heparan sulfate proteoglycan biosynthetic process, enzymatic modification [GO:0015015]; negative regulation of coagulation [GO:0050819]; protein sulfation [GO:0006477]; regulation of viral entry into host cell [GO:0046596] GO:0000139; GO:0006477; GO:0008467; GO:0015012; GO:0015015; GO:0046596; GO:0050819 30542 XM_044311854.1 1 0 4 13 2 NA NA NA NA NA NA 30543 XM_029341778.2 13 26 15 32 14 A2RSY1 8.88e-154 KAT8 regulatory NSL complex subunit 3 (NSL complex protein NSL3) (Non-specific lethal 3 homolog) Mus musculus (Mouse) chromatin organization [GO:0006325]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of dosage compensation by inactivation of X chromosome [GO:1900095] GO:0000123; GO:0005654; GO:0006325; GO:0043231; GO:0043981; GO:0043982; GO:0043984; GO:0044545; GO:0045893; GO:0045944; GO:0051571; GO:1900095 30544 XM_044317083.1 0 13 0 0 0 P36544 9.69e-85 Neuronal acetylcholine receptor subunit alpha-7 Homo sapiens (Human) acetylcholine receptor signaling pathway [GO:0095500]; calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; cognition [GO:0050890]; dendrite arborization [GO:0140059]; dendritic spine organization [GO:0097061]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; learning or memory [GO:0007611]; membrane depolarization [GO:0051899]; memory [GO:0007613]; modulation of excitatory postsynaptic potential [GO:0098815]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of tumor necrosis factor production [GO:0032720]; nervous system process [GO:0050877]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of CoA-transferase activity [GO:1905920]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; regulation of amyloid fibril formation [GO:1905906]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of membrane potential [GO:0042391]; regulation of neuron death [GO:1901214]; regulation of nitric oxide metabolic process [GO:0080164]; response to acetylcholine [GO:1905144]; response to amyloid-beta [GO:1904645]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; sensory processing [GO:0050893]; short-term memory [GO:0007614]; signal transduction [GO:0007165]; synapse organization [GO:0050808]; synaptic transmission, cholinergic [GO:0007271] GO:0001540; GO:0001666; GO:0001934; GO:0005216; GO:0005231; GO:0005262; GO:0005886; GO:0005892; GO:0006811; GO:0006816; GO:0006874; GO:0007165; GO:0007268; GO:0007271; GO:0007611; GO:0007613; GO:0007614; GO:0008284; GO:0015464; GO:0015643; GO:0016020; GO:0017081; GO:0022848; GO:0030594; GO:0032720; GO:0034220; GO:0035094; GO:0042166; GO:0042391; GO:0042803; GO:0043005; GO:0043410; GO:0044853; GO:0045202; GO:0045211; GO:0045766; GO:0050808; GO:0050877; GO:0050890; GO:0050893; GO:0051247; GO:0051899; GO:0070374; GO:0080164; GO:0095500; GO:0097061; GO:0098794; GO:0098815; GO:0140059; GO:1900273; GO:1901214; GO:1902004; GO:1902430; GO:1902991; GO:1904315; GO:1904645; GO:1905144; GO:1905906; GO:1905920; GO:2000463 30545 XM_044313135.1 435 173 203 351 320 NA NA NA NA NA NA 30546 XM_029330726.2 97659 62736 38358 78599 54650 P08761 1.06e-33 Peptide methionine sulfoxide reductase (EC 1.8.4.11) (Ecdysone-induced protein 28/29 kDa) (Methionine-S-sulfoxide reductase) (Peptide-methionine (S)-S-oxide reductase) Drosophila melanogaster (Fruit fly) cellular response to oxidative stress [GO:0034599]; determination of adult lifespan [GO:0008340]; response to oxidative stress [GO:0006979]; sulfur amino acid metabolic process [GO:0000096] GO:0000096; GO:0005737; GO:0006979; GO:0008113; GO:0008340; GO:0034599; GO:0036456 30547 XM_029330726.2 97659 62736 38358 78599 54650 P08761 1.06e-33 Peptide methionine sulfoxide reductase (EC 1.8.4.11) (Ecdysone-induced protein 28/29 kDa) (Methionine-S-sulfoxide reductase) (Peptide-methionine (S)-S-oxide reductase) Drosophila melanogaster (Fruit fly) cellular response to oxidative stress [GO:0034599]; determination of adult lifespan [GO:0008340]; response to oxidative stress [GO:0006979]; sulfur amino acid metabolic process [GO:0000096] GO:0000096; GO:0005737; GO:0006979; GO:0008113; GO:0008340; GO:0034599; GO:0036456 30548 XM_044321436.1 91 147 35 23 49 W7LUF3 9.12e-40 Dehydrogenase FUM7 (EC 1.14.11.-) (Fumonisin biosynthesis cluster protein 7) Gibberella moniliformis (strain M3125 / FGSC 7600) (Maize ear and stalk rot fungus) (Fusarium verticillioides) fumonisin biosynthetic process [GO:1900541] GO:0016491; GO:0046872; GO:1900541 30549 XM_029328166.2 11 1 17 6 50 NA NA NA NA NA NA 30550 XM_029340920.2 925 845 784 1409 810 Q3V3N7 0 Bardet-Biedl syndrome 1 protein homolog Mus musculus (Mouse) adult behavior [GO:0030534]; brain morphogenesis [GO:0048854]; cartilage development [GO:0051216]; cellular lipid metabolic process [GO:0044255]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; dendrite development [GO:0016358]; fat cell differentiation [GO:0045444]; fertilization [GO:0009566]; Golgi to plasma membrane protein transport [GO:0043001]; hippocampus development [GO:0021766]; hormone metabolic process [GO:0042445]; intraciliary retrograde transport [GO:0035721]; microtubule cytoskeleton organization [GO:0000226]; neural precursor cell proliferation [GO:0061351]; neuron migration [GO:0001764]; non-motile cilium assembly [GO:1905515]; olfactory behavior [GO:0042048]; photoreceptor cell maintenance [GO:0045494]; photoreceptor cell morphogenesis [GO:0008594]; protein localization [GO:0008104]; protein localization to cilium [GO:0061512]; regulation of cilium beat frequency involved in ciliary motility [GO:0060296]; retina homeostasis [GO:0001895]; sensory perception of smell [GO:0007608]; striatum development [GO:0021756]; ventricular system development [GO:0021591]; visual perception [GO:0007601] GO:0000226; GO:0001764; GO:0001895; GO:0005102; GO:0005113; GO:0005119; GO:0005813; GO:0005929; GO:0005930; GO:0007601; GO:0007608; GO:0008104; GO:0008594; GO:0009566; GO:0016358; GO:0021591; GO:0021756; GO:0021766; GO:0021987; GO:0030534; GO:0031514; GO:0034451; GO:0034464; GO:0035721; GO:0036064; GO:0042048; GO:0042445; GO:0043001; GO:0044255; GO:0045444; GO:0045494; GO:0048854; GO:0051216; GO:0051219; GO:0060170; GO:0060271; GO:0060296; GO:0061351; GO:0061512; GO:0061629; GO:1905515 30551 XM_044328956.1 70 90 35 213 35 Q15822 3.52e-87 Neuronal acetylcholine receptor subunit alpha-2 Homo sapiens (Human) cellular response to nicotine [GO:0071316]; chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; membrane depolarization [GO:0051899]; modulation of inhibitory postsynaptic potential [GO:0098828]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; response to acetylcholine [GO:1905144]; response to nicotine [GO:0035094]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271] GO:0005231; GO:0005654; GO:0005886; GO:0005892; GO:0006811; GO:0007165; GO:0007268; GO:0007271; GO:0015464; GO:0016020; GO:0022848; GO:0030594; GO:0034220; GO:0035094; GO:0042391; GO:0043005; GO:0045171; GO:0045202; GO:0045211; GO:0050877; GO:0050997; GO:0051899; GO:0071316; GO:0098828; GO:0120111; GO:1901363; GO:1904315; GO:1905144 30552 XM_029357496.2 0 0 0 36 0 P23824 4.03e-70 GATA-binding factor 2 (GATA-2) (Transcription factor NF-E1b) Gallus gallus (Chicken) cell fate commitment [GO:0045165]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of angiogenesis [GO:0045766]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000122; GO:0000978; GO:0000981; GO:0001223; GO:0005634; GO:0008270; GO:0045165; GO:0045766; GO:0045944; GO:1902895 30553 XM_044328044.1 441 444 212 493 621 P42125 2.44e-60 Enoyl-CoA delta isomerase 1, mitochondrial (EC 5.3.3.8) (3,2-trans-enoyl-CoA isomerase) (Delta(3),Delta(2)-enoyl-CoA isomerase) (D3,D2-enoyl-CoA isomerase) (Dodecenoyl-CoA isomerase) Mus musculus (Mouse) fatty acid beta-oxidation [GO:0006635] GO:0004165; GO:0005739; GO:0005743; GO:0005759; GO:0006635; GO:0016863; GO:0042802 30554 XR_006391907.1 0 0 2 1 22 NA NA NA NA NA NA 30555 XM_029336476.2 6514 4563 3919 5716 6856 A7S338 0 Lissencephaly-1 homolog Nematostella vectensis (Starlet sea anemone) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; microtubule organizing center organization [GO:0031023]; microtubule sliding [GO:0051012]; nuclear migration [GO:0007097]; vesicle transport along microtubule [GO:0047496] GO:0000132; GO:0000776; GO:0005635; GO:0005815; GO:0005875; GO:0005881; GO:0007097; GO:0031023; GO:0047496; GO:0051010; GO:0051012; GO:0051301; GO:0070840 30556 XM_044310062.1 0 0 46 8 0 NA NA NA NA NA NA 30557 XM_044317909.1 376 259 196 220 338 B8JMH0 2.01e-60 Putative transferase CAF17 homolog, mitochondrial (EC 2.1.-.-) (Iron-sulfur cluster assembly factor homolog) Danio rerio (Zebrafish) (Brachydanio rerio) heme biosynthetic process [GO:0006783]; iron-sulfur cluster assembly [GO:0016226] GO:0005759; GO:0006783; GO:0016226; GO:0016740 30558 XR_003824783.2 0 0 0 6 0 NA NA NA NA NA NA 30559 XM_029326764.2 440 505 9 622 375 P31230 1.04e-76 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (Multisynthase complex auxiliary component p43) [Cleaved into: Endothelial monocyte-activating polypeptide 2 (EMAP-2) (Endothelial monocyte-activating polypeptide II) (EMAP-II) (Small inducible cytokine subfamily E member 1)] Mus musculus (Mouse) angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell-cell signaling [GO:0007267]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; negative regulation of endothelial cell proliferation [GO:0001937]; positive regulation of glucagon secretion [GO:0070094]; translation [GO:0006412] GO:0000049; GO:0001525; GO:0001937; GO:0005125; GO:0005615; GO:0005634; GO:0005783; GO:0005794; GO:0005829; GO:0006412; GO:0006915; GO:0006954; GO:0007267; GO:0009986; GO:0017101; GO:0042803; GO:0050900; GO:0051020; GO:0070094 30560 XM_029324793.2 16 0 0 6 1 NA NA NA NA NA NA 30561 XM_029334918.2 684 302 262 279 145 Q9ES34 0 Ubiquitin-protein ligase E3B (EC 2.3.2.26) (HECT-type ubiquitin transferase E3B) Mus musculus (Mouse) protein polyubiquitination [GO:0000209]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000209; GO:0006511; GO:0061630 30562 XM_029334540.2 0 0 11 0 0 NA NA NA NA NA NA 30563 XM_029337804.2 557 417 427 611 456 NA NA NA NA NA NA 30564 XM_029357619.2 303 513 269 494 1001 NA NA NA NA NA NA 30565 XM_044326901.1 514 107 0 260 75 NA NA NA NA NA NA 30566 XM_029333352.2 458 697 321 388 338 Q7Z5U6 6.02e-54 WD repeat-containing protein 53 Homo sapiens (Human) NA NA 30567 XM_029346824.2 90 0 177 324 190 Q9ULL1 1.56e-94 Pleckstrin homology domain-containing family G member 1 Homo sapiens (Human) regulation of small GTPase mediated signal transduction [GO:0051056] GO:0005085; GO:0005654; GO:0005829; GO:0051056 30568 XM_029334716.2 503 684 217 494 609 Q66JY2 8.05e-39 INO80 complex subunit D Mus musculus (Mouse) chromatin remodeling [GO:0006338]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of telomere maintenance in response to DNA damage [GO:1904507]; regulation of cell cycle [GO:0051726]; regulation of chromosome organization [GO:0033044]; regulation of DNA repair [GO:0006282]; regulation of DNA replication [GO:0006275]; regulation of DNA strand elongation [GO:0060382]; regulation of embryonic development [GO:0045995]; telomere maintenance [GO:0000723] GO:0000723; GO:0005634; GO:0006275; GO:0006281; GO:0006282; GO:0006310; GO:0006338; GO:0031011; GO:0033044; GO:0045739; GO:0045893; GO:0045995; GO:0051726; GO:0060382; GO:1904507 30569 XM_029329940.2 0 89 0 0 0 Q9NSA2 9.42e-65 Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) Homo sapiens (Human) potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005250; GO:0005886; GO:0008076; GO:0014069; GO:0016020; GO:0034765; GO:0043025; GO:0043197; GO:0045211; GO:0046872; GO:0051260; GO:0071805 30570 XM_029337013.2 19 0 0 38 0 B8RJM0 0 Uncharacterized skeletal organic matrix protein 3 (Uncharacterized SOMP-3) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 30571 XM_044309753.1 244 40 120 423 553 P10079 0 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 30572 XM_044309753.1 244 40 120 423 553 P10079 0 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 30573 XM_044309753.1 244 40 120 423 553 P10079 0 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 30574 XM_044309753.1 244 40 120 423 553 P10079 0 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 30575 XM_044309753.1 244 40 120 423 553 P10079 0 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 30576 XM_044309753.1 244 40 120 423 553 P10079 6.11e-97 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 30577 XM_029353949.2 907 1045 1085 967 1176 Q8VDL4 7.28e-42 ADP-dependent glucokinase (ADP-GK) (ADPGK) (EC 2.7.1.147) Mus musculus (Mouse) carbohydrate metabolic process [GO:0005975]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096] GO:0005576; GO:0005783; GO:0005975; GO:0006006; GO:0006096; GO:0043843; GO:0046872 30578 XM_044318159.1 88 0 557 451 395 P49024 5.84e-149 Paxillin Gallus gallus (Chicken) endothelial cell migration [GO:0043542]; response to muscle stretch [GO:0035994]; substrate adhesion-dependent cell spreading [GO:0034446]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001725; GO:0003712; GO:0005829; GO:0005886; GO:0005925; GO:0005938; GO:0007179; GO:0017166; GO:0034446; GO:0035994; GO:0043542; GO:0046872 30579 XM_029350911.2 0 31 0 0 0 NA NA NA NA NA NA 30580 XM_029347534.2 1768 1828 1351 1859 1635 P63172 7.56e-69 Dynein light chain Tctex-type 1 (Protein CW-1) (T-complex testis-specific protein 1 homolog) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; intracellular transport of viral protein in host cell [GO:0019060]; microtubule-based movement [GO:0007018]; microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; negative regulation of neurogenesis [GO:0050768]; nervous system development [GO:0007399]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; viral entry into host cell [GO:0046718] GO:0000132; GO:0005576; GO:0005737; GO:0005794; GO:0005819; GO:0005868; GO:0005881; GO:0007018; GO:0007399; GO:0008277; GO:0019060; GO:0030286; GO:0034774; GO:0042802; GO:0043657; GO:0045505; GO:0046718; GO:0050768; GO:0051301; GO:0075521; GO:0099503; GO:1904813 30581 XM_029334440.2 1350 630 1007 876 1087 Q9HCG1 8.18e-79 Zinc finger protein 160 (Zinc finger protein HZF5) (Zinc finger protein Kr18) (HKr18) Homo sapiens (Human) hemopoiesis [GO:0030097]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0030097; GO:0046872 30582 XM_029334440.2 1350 630 1007 876 1087 Q9HCG1 4.63e-39 Zinc finger protein 160 (Zinc finger protein HZF5) (Zinc finger protein Kr18) (HKr18) Homo sapiens (Human) hemopoiesis [GO:0030097]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0030097; GO:0046872 30583 XM_029334440.2 1350 630 1007 876 1087 Q9HCG1 9.22e-38 Zinc finger protein 160 (Zinc finger protein HZF5) (Zinc finger protein Kr18) (HKr18) Homo sapiens (Human) hemopoiesis [GO:0030097]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0030097; GO:0046872 30584 XM_029334440.2 1350 630 1007 876 1087 Q9HCG1 1.59e-37 Zinc finger protein 160 (Zinc finger protein HZF5) (Zinc finger protein Kr18) (HKr18) Homo sapiens (Human) hemopoiesis [GO:0030097]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0030097; GO:0046872 30585 XM_029334440.2 1350 630 1007 876 1087 Q9HCG1 2.57e-37 Zinc finger protein 160 (Zinc finger protein HZF5) (Zinc finger protein Kr18) (HKr18) Homo sapiens (Human) hemopoiesis [GO:0030097]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0030097; GO:0046872 30586 XM_029334440.2 1350 630 1007 876 1087 Q9HCG1 6.3e-37 Zinc finger protein 160 (Zinc finger protein HZF5) (Zinc finger protein Kr18) (HKr18) Homo sapiens (Human) hemopoiesis [GO:0030097]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0030097; GO:0046872 30587 XM_029334440.2 1350 630 1007 876 1087 Q9HCG1 1.32e-36 Zinc finger protein 160 (Zinc finger protein HZF5) (Zinc finger protein Kr18) (HKr18) Homo sapiens (Human) hemopoiesis [GO:0030097]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0030097; GO:0046872 30588 XM_029334440.2 1350 630 1007 876 1087 Q9HCG1 1.71e-36 Zinc finger protein 160 (Zinc finger protein HZF5) (Zinc finger protein Kr18) (HKr18) Homo sapiens (Human) hemopoiesis [GO:0030097]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0030097; GO:0046872 30589 XM_029334440.2 1350 630 1007 876 1087 Q9HCG1 1.97e-36 Zinc finger protein 160 (Zinc finger protein HZF5) (Zinc finger protein Kr18) (HKr18) Homo sapiens (Human) hemopoiesis [GO:0030097]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0030097; GO:0046872 30590 XM_029334440.2 1350 630 1007 876 1087 Q9HCG1 2.77e-36 Zinc finger protein 160 (Zinc finger protein HZF5) (Zinc finger protein Kr18) (HKr18) Homo sapiens (Human) hemopoiesis [GO:0030097]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0030097; GO:0046872 30591 XM_029334440.2 1350 630 1007 876 1087 Q9HCG1 3.93e-36 Zinc finger protein 160 (Zinc finger protein HZF5) (Zinc finger protein Kr18) (HKr18) Homo sapiens (Human) hemopoiesis [GO:0030097]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0030097; GO:0046872 30592 XM_029334440.2 1350 630 1007 876 1087 Q9HCG1 5.03e-36 Zinc finger protein 160 (Zinc finger protein HZF5) (Zinc finger protein Kr18) (HKr18) Homo sapiens (Human) hemopoiesis [GO:0030097]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0030097; GO:0046872 30593 XM_029334440.2 1350 630 1007 876 1087 Q9HCG1 1e-35 Zinc finger protein 160 (Zinc finger protein HZF5) (Zinc finger protein Kr18) (HKr18) Homo sapiens (Human) hemopoiesis [GO:0030097]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0030097; GO:0046872 30594 XM_029334440.2 1350 630 1007 876 1087 Q9HCG1 1.13e-35 Zinc finger protein 160 (Zinc finger protein HZF5) (Zinc finger protein Kr18) (HKr18) Homo sapiens (Human) hemopoiesis [GO:0030097]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0030097; GO:0046872 30595 XM_029334440.2 1350 630 1007 876 1087 Q9HCG1 1.47e-35 Zinc finger protein 160 (Zinc finger protein HZF5) (Zinc finger protein Kr18) (HKr18) Homo sapiens (Human) hemopoiesis [GO:0030097]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0030097; GO:0046872 30596 XM_029334440.2 1350 630 1007 876 1087 Q9HCG1 3.89e-35 Zinc finger protein 160 (Zinc finger protein HZF5) (Zinc finger protein Kr18) (HKr18) Homo sapiens (Human) hemopoiesis [GO:0030097]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0030097; GO:0046872 30597 XM_029334440.2 1350 630 1007 876 1087 Q9HCG1 5.62e-35 Zinc finger protein 160 (Zinc finger protein HZF5) (Zinc finger protein Kr18) (HKr18) Homo sapiens (Human) hemopoiesis [GO:0030097]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0030097; GO:0046872 30598 XM_029334440.2 1350 630 1007 876 1087 Q9HCG1 7.76e-35 Zinc finger protein 160 (Zinc finger protein HZF5) (Zinc finger protein Kr18) (HKr18) Homo sapiens (Human) hemopoiesis [GO:0030097]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0030097; GO:0046872 30599 XM_029334440.2 1350 630 1007 876 1087 Q9HCG1 1.56e-34 Zinc finger protein 160 (Zinc finger protein HZF5) (Zinc finger protein Kr18) (HKr18) Homo sapiens (Human) hemopoiesis [GO:0030097]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0030097; GO:0046872 30600 XM_029334440.2 1350 630 1007 876 1087 Q9HCG1 2.82e-34 Zinc finger protein 160 (Zinc finger protein HZF5) (Zinc finger protein Kr18) (HKr18) Homo sapiens (Human) hemopoiesis [GO:0030097]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0030097; GO:0046872 30601 XM_029334440.2 1350 630 1007 876 1087 Q9HCG1 1.05e-33 Zinc finger protein 160 (Zinc finger protein HZF5) (Zinc finger protein Kr18) (HKr18) Homo sapiens (Human) hemopoiesis [GO:0030097]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0030097; GO:0046872 30602 XM_029334440.2 1350 630 1007 876 1087 Q9HCG1 5.28e-33 Zinc finger protein 160 (Zinc finger protein HZF5) (Zinc finger protein Kr18) (HKr18) Homo sapiens (Human) hemopoiesis [GO:0030097]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0030097; GO:0046872 30603 XM_029334440.2 1350 630 1007 876 1087 Q9HCG1 1.43e-28 Zinc finger protein 160 (Zinc finger protein HZF5) (Zinc finger protein Kr18) (HKr18) Homo sapiens (Human) hemopoiesis [GO:0030097]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0030097; GO:0046872 30604 XM_029340067.2 6 0 4 0 40 NA NA NA NA NA NA 30605 XM_029338766.2 1043 1039 519 783 964 P42325 2.38e-119 Neurocalcin homolog (DrosNCa) Drosophila melanogaster (Fruit fly) negative regulation of neuronal signal transduction [GO:1902848]; positive regulation of circadian sleep/wake cycle, sleep [GO:0045938] GO:0005509; GO:0045938; GO:1902848 30606 XM_044320755.1 4 9 8 0 14 NA NA NA NA NA NA 30607 XM_029358079.2 0 0 1 16 5 NA NA NA NA NA NA 30608 XM_044320030.1 15 5 12 50 33 P21328 3.81e-25 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 30609 XM_044322316.1 0 0 0 123 0 NA NA NA NA NA NA 30610 XM_029356991.2 5388 5060 2847 8348 8174 Q8IVL0 2e-65 Neuron navigator 3 (Pore membrane and/or filament-interacting-like protein 1) (Steerin-3) (Unc-53 homolog 3) (unc53H3) Homo sapiens (Human) negative regulation of cell migration [GO:0030336]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of microtubule depolymerization [GO:0007026]; nervous system development [GO:0007399]; neurogenesis [GO:0022008]; positive regulation of microtubule polymerization [GO:0031116] GO:0005524; GO:0005640; GO:0007026; GO:0007399; GO:0008017; GO:0016887; GO:0022008; GO:0030336; GO:0031116; GO:0032703 30611 XM_044319733.1 11418 8949 7477 9901 2046 NA NA NA NA NA NA 30612 XM_029337234.2 0 465 99 148 9 NA NA NA NA NA NA 30613 XR_006392221.1 514 397 236 345 345 NA NA NA NA NA NA 30614 XM_029323653.2 44 169 189 218 144 NA NA NA NA NA NA 30615 XM_044317529.1 72 38 72 4 135 NA NA NA NA NA NA 30616 XM_044318969.1 29 0 30 16 83 P10394 1.35e-62 Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 30617 XR_003822700.2 4241 4235 3900 4049 3617 NA NA NA NA NA NA 30618 XM_029352723.2 50 20 23 27 17 NA NA NA NA NA NA 30619 XR_006391736.1 4 5 9 7 1 Q96DM1 5.08e-44 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 30620 XM_029325285.2 17 9 6 4 12 P68373 3.51e-118 Tubulin alpha-1C chain (EC 3.6.5.-) (Alpha-tubulin 6) (Alpha-tubulin isotype M-alpha-6) (Tubulin alpha-6 chain) [Cleaved into: Detyrosinated tubulin alpha-1C chain] Mus musculus (Mouse) microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278] GO:0000226; GO:0000278; GO:0005200; GO:0005525; GO:0005634; GO:0005737; GO:0005874; GO:0005881; GO:0015630; GO:0016787; GO:0045121; GO:0046872 30621 XM_044321223.1 0 0 0 9 3 NA NA NA NA NA NA 30622 XR_003822967.2 47 30 65 115 33 NA NA NA NA NA NA 30623 XM_044321424.1 1299 947 659 2133 1798 NA NA NA NA NA NA 30624 XM_044323104.1 1090 848 577 1168 1299 Q9NVE5 0 Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.4.19.12) (Deubiquitinating enzyme 40) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40) Homo sapiens (Human) protein deubiquitination [GO:0016579]; regulation of protein stability [GO:0031647]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004197; GO:0004843; GO:0005634; GO:0005829; GO:0006511; GO:0016579; GO:0031647 30625 XM_044327666.1 9 194 64 50 29 NA NA NA NA NA NA 30626 XM_044310774.1 0 29 43 0 10 NA NA NA NA NA NA 30627 XM_029352731.2 0 5 1 8 1 NA NA NA NA NA NA 30628 XM_029340666.2 1234 412 708 2257 2697 Q6P0C6 2.48e-48 LHFPL tetraspan subfamily member 2a protein Danio rerio (Zebrafish) (Brachydanio rerio) development of primary female sexual characteristics [GO:0046545]; development of primary male sexual characteristics [GO:0046546]; positive regulation of fertilization [GO:1905516]; single fertilization [GO:0007338] GO:0007338; GO:0016020; GO:0046545; GO:0046546; GO:1905516 30629 XM_029336447.2 67 54 60 0 53 NA NA NA NA NA NA 30630 XM_044322188.1 11 2 6 7 0 NA NA NA NA NA NA 30631 XM_044322959.1 1542 1512 1028 1563 707 P84079 1.69e-117 ADP-ribosylation factor 1 (EC 3.6.5.2) Rattus norvegicus (Rat) actin filament organization [GO:0007015]; cellular copper ion homeostasis [GO:0006878]; cellular response to virus [GO:0098586]; dendritic spine organization [GO:0097061]; Golgi to transport vesicle transport [GO:0055108]; intracellular protein transport [GO:0006886]; long-term synaptic depression [GO:0060292]; lysosomal membrane organization [GO:0097212]; mitotic cleavage furrow ingression [GO:1990386]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of endocytosis [GO:0045807]; positive regulation of ER to Golgi vesicle-mediated transport [GO:1902953]; positive regulation of late endosome to lysosome transport [GO:1902824]; positive regulation of protein secretion [GO:0050714]; positive regulation of sodium ion transmembrane transport [GO:1902307]; postsynaptic actin cytoskeleton organization [GO:0098974]; regulation of Arp2/3 complex-mediated actin nucleation [GO:0034315]; regulation of phospholipid metabolic process [GO:1903725]; regulation of receptor internalization [GO:0002090]; synaptic vesicle budding [GO:0070142]; very-low-density lipoprotein particle assembly [GO:0034379]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0000287; GO:0002090; GO:0003924; GO:0005525; GO:0005737; GO:0005770; GO:0005794; GO:0005829; GO:0005886; GO:0006878; GO:0006886; GO:0007015; GO:0012505; GO:0014069; GO:0016192; GO:0019003; GO:0019904; GO:0030017; GO:0031252; GO:0032991; GO:0034315; GO:0034379; GO:0043005; GO:0045807; GO:0045956; GO:0050714; GO:0055108; GO:0060292; GO:0060999; GO:0070142; GO:0097061; GO:0097212; GO:0098586; GO:0098974; GO:0098978; GO:1902307; GO:1902824; GO:1902953; GO:1903725; GO:1990386; GO:1990583 30632 XM_044309319.1 0 44 31 11 4 NA NA NA NA NA NA 30633 XM_029341124.2 261 465 125 150 132 P21802 5.35e-149 Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332) Homo sapiens (Human) angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell fate commitment [GO:0045165]; cell-cell signaling [GO:0007267]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; lung-associated mesenchyme development [GO:0060484]; mammary gland bud formation [GO:0060615]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smooth muscle cell differentiation [GO:0051150]; regulation of smoothened signaling pathway [GO:0008589]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060] GO:0000122; GO:0001525; GO:0001657; GO:0001701; GO:0001837; GO:0002053; GO:0003148; GO:0003149; GO:0003416; GO:0004713; GO:0004714; GO:0005007; GO:0005524; GO:0005576; GO:0005634; GO:0005737; GO:0005794; GO:0005886; GO:0005938; GO:0006915; GO:0007169; GO:0007267; GO:0007409; GO:0008201; GO:0008284; GO:0008543; GO:0008589; GO:0009791; GO:0009880; GO:0009887; GO:0009986; GO:0010518; GO:0010839; GO:0016020; GO:0016331; GO:0017134; GO:0018108; GO:0021769; GO:0021847; GO:0021860; GO:0022612; GO:0030177; GO:0030282; GO:0030324; GO:0030855; GO:0030901; GO:0030916; GO:0031069; GO:0031410; GO:0032496; GO:0032808; GO:0033674; GO:0033688; GO:0035265; GO:0035602; GO:0035603; GO:0035604; GO:0035607; GO:0042060; GO:0042472; GO:0042476; GO:0042802; GO:0042803; GO:0043235; GO:0043410; GO:0045165; GO:0045471; GO:0045667; GO:0045787; GO:0045944; GO:0046777; GO:0048286; GO:0048333; GO:0048557; GO:0048562; GO:0048565; GO:0048568; GO:0048608; GO:0048661; GO:0048701; GO:0048705; GO:0048730; GO:0048755; GO:0048762; GO:0050679; GO:0051150; GO:0051781; GO:0055010; GO:0060045; GO:0060076; GO:0060174; GO:0060348; GO:0060349; GO:0060442; GO:0060445; GO:0060449; GO:0060463; GO:0060484; GO:0060501; GO:0060512; GO:0060523; GO:0060527; GO:0060529; GO:0060595; GO:0060601; GO:0060615; GO:0060664; GO:0060667; GO:0060670; GO:0060688; GO:0060915; GO:0060916; GO:0070372; GO:0070374; GO:0071300; GO:0071560; GO:0090263 30634 XM_029347392.2 1757 1019 1399 1438 887 NA NA NA NA NA NA 30635 XM_044328303.1 100 117 30 74 63 NA NA NA NA NA NA 30636 XM_029330448.2 2 0 1 11 14 P10608 6.2e-33 Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor) Rattus norvegicus (Rat) activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; associative learning [GO:0008306]; bone resorption [GO:0045453]; brown fat cell differentiation [GO:0050873]; cellular response to amyloid-beta [GO:1904646]; cellular response to hypoxia [GO:0071456]; desensitization of G protein-coupled receptor signaling pathway by arrestin [GO:0002032]; diaphragm contraction [GO:0002086]; diet induced thermogenesis [GO:0002024]; estrous cycle [GO:0044849]; excitatory postsynaptic potential [GO:0060079]; female pregnancy [GO:0007565]; G protein-coupled receptor signaling pathway [GO:0007186]; heat generation [GO:0031649]; liver development [GO:0001889]; liver regeneration [GO:0097421]; negative regulation of angiogenesis [GO:0016525]; negative regulation of inflammatory response [GO:0050728]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of ossification [GO:0030279]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of urine volume [GO:0035811]; norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0002025]; positive regulation of AMPA receptor activity [GO:2000969]; positive regulation of apoptotic process [GO:0043065]; positive regulation of ATP-dependent activity [GO:0032781]; positive regulation of autophagosome maturation [GO:1901098]; positive regulation of bone mineralization [GO:0030501]; positive regulation of calcium ion import across plasma membrane [GO:1905665]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of heart contraction [GO:0045823]; positive regulation of lipophagy [GO:1904504]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mini excitatory postsynaptic potential [GO:0061885]; positive regulation of potassium ion transport [GO:0043268]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of skeletal muscle tissue growth [GO:0048633]; positive regulation of sodium ion transport [GO:0010765]; positive regulation of the force of heart contraction by epinephrine [GO:0003059]; positive regulation of transcription by RNA polymerase II [GO:0045944]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; receptor-mediated endocytosis [GO:0006898]; regulation of calcium ion transport [GO:0051924]; regulation of sensory perception of pain [GO:0051930]; regulation of sodium ion transport [GO:0002028]; regulation of systemic arterial blood pressure by norepinephrine-epinephrine [GO:0001993]; response to catecholamine [GO:0071869]; response to cold [GO:0009409]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to hypoxia [GO:0001666]; response to monoamine [GO:0071867]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]; smooth muscle contraction [GO:0006939]; synaptic transmission, glutamatergic [GO:0035249]; transcription by RNA polymerase II [GO:0006366]; vasodilation [GO:0042311]; wound healing [GO:0042060] GO:0001540; GO:0001666; GO:0001889; GO:0001965; GO:0001993; GO:0002024; GO:0002025; GO:0002028; GO:0002032; GO:0002086; GO:0003059; GO:0004930; GO:0004941; GO:0005634; GO:0005737; GO:0005768; GO:0005769; GO:0005794; GO:0005886; GO:0005901; GO:0006366; GO:0006898; GO:0006939; GO:0007186; GO:0007189; GO:0007190; GO:0007565; GO:0007568; GO:0008179; GO:0008284; GO:0008306; GO:0009409; GO:0010739; GO:0010765; GO:0015459; GO:0016020; GO:0016324; GO:0016525; GO:0019899; GO:0030165; GO:0030279; GO:0030424; GO:0030425; GO:0030501; GO:0031649; GO:0031713; GO:0032570; GO:0032781; GO:0032809; GO:0033574; GO:0035249; GO:0035255; GO:0035811; GO:0040015; GO:0042060; GO:0042311; GO:0042383; GO:0042802; GO:0042803; GO:0043065; GO:0043197; GO:0043231; GO:0043235; GO:0043268; GO:0043410; GO:0043627; GO:0044849; GO:0044877; GO:0045211; GO:0045453; GO:0045823; GO:0045944; GO:0045986; GO:0048633; GO:0050728; GO:0050873; GO:0051379; GO:0051380; GO:0051721; GO:0051924; GO:0051930; GO:0060079; GO:0061885; GO:0071456; GO:0071548; GO:0071867; GO:0071869; GO:0071875; GO:0071880; GO:0071902; GO:0090331; GO:0090722; GO:0097421; GO:0098685; GO:0098793; GO:0098978; GO:0098992; GO:0099171; GO:0120162; GO:1901098; GO:1904504; GO:1904646; GO:1905665; GO:2000969 30637 XM_029330398.2 241 48 59 394 226 NA NA NA NA NA NA 30638 XM_044309144.1 4102 2682 1574 3468 3091 P09327 1.55e-179 Villin-1 Homo sapiens (Human) actin filament capping [GO:0051693]; actin filament depolymerization [GO:0030042]; actin filament polymerization [GO:0030041]; actin filament severing [GO:0051014]; actin polymerization or depolymerization [GO:0008154]; barbed-end actin filament capping [GO:0051016]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cytoplasmic actin-based contraction involved in cell motility [GO:0060327]; epidermal growth factor receptor signaling pathway [GO:0007173]; epithelial cell differentiation [GO:0030855]; intestinal D-glucose absorption [GO:0001951]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of actin filament depolymerization [GO:0030836]; positive regulation of cell migration [GO:0030335]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein-containing complex assembly [GO:0065003]; regulation of actin nucleation [GO:0051125]; regulation of cell shape [GO:0008360]; regulation of lamellipodium morphogenesis [GO:2000392]; regulation of microvillus length [GO:0032532]; regulation of wound healing [GO:0061041]; response to bacterium [GO:0009617]; terminal web assembly [GO:1902896] GO:0001726; GO:0001951; GO:0005509; GO:0005546; GO:0005737; GO:0005886; GO:0005902; GO:0005903; GO:0007173; GO:0008154; GO:0008360; GO:0009617; GO:0010634; GO:0015629; GO:0030027; GO:0030041; GO:0030042; GO:0030175; GO:0030335; GO:0030836; GO:0030855; GO:0032233; GO:0032432; GO:0032433; GO:0032532; GO:0035727; GO:0035729; GO:0040018; GO:0042802; GO:0042803; GO:0043027; GO:0051014; GO:0051015; GO:0051016; GO:0051125; GO:0051693; GO:0060327; GO:0061041; GO:0065003; GO:0070062; GO:0071364; GO:1902896; GO:1903078; GO:2000392; GO:2000394 30639 XM_029324802.2 1218 695 698 1643 1221 E1BPK6 0 Unconventional myosin-VI (Unconventional myosin-6) Bos taurus (Bovine) actin filament organization [GO:0007015]; endocytosis [GO:0006897]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear morphogenesis [GO:0042472]; protein transport [GO:0015031]; sensory perception of sound [GO:0007605]; vesicle transport along actin filament [GO:0030050] GO:0000146; GO:0001726; GO:0005516; GO:0005524; GO:0005634; GO:0005737; GO:0005794; GO:0005829; GO:0005886; GO:0005902; GO:0005905; GO:0006897; GO:0007015; GO:0007605; GO:0015031; GO:0015629; GO:0016459; GO:0030050; GO:0030136; GO:0030139; GO:0030175; GO:0031982; GO:0032587; GO:0042472; GO:0042491; GO:0048471; GO:0051015 30640 XM_029324802.2 1218 695 698 1643 1221 E1BPK6 1.3e-59 Unconventional myosin-VI (Unconventional myosin-6) Bos taurus (Bovine) actin filament organization [GO:0007015]; endocytosis [GO:0006897]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear morphogenesis [GO:0042472]; protein transport [GO:0015031]; sensory perception of sound [GO:0007605]; vesicle transport along actin filament [GO:0030050] GO:0000146; GO:0001726; GO:0005516; GO:0005524; GO:0005634; GO:0005737; GO:0005794; GO:0005829; GO:0005886; GO:0005902; GO:0005905; GO:0006897; GO:0007015; GO:0007605; GO:0015031; GO:0015629; GO:0016459; GO:0030050; GO:0030136; GO:0030139; GO:0030175; GO:0031982; GO:0032587; GO:0042472; GO:0042491; GO:0048471; GO:0051015 30641 XM_044313289.1 3 9 5 18 8 NA NA NA NA NA NA 30642 XR_006397994.1 27 0 0 0 0 NA NA NA NA NA NA 30643 XM_044323496.1 0 0 23 6 3 NA NA NA NA NA NA 30644 XR_006395570.1 8 0 0 0 0 NA NA NA NA NA NA 30645 XM_029335605.2 60 82 137 137 62 NA NA NA NA NA NA 30646 XM_029353763.2 258 116 14 354 138 NA NA NA NA NA NA 30647 XM_044314989.1 8 0 0 2 0 NA NA NA NA NA NA 30648 XM_029357244.2 106 124 68 63 71 NA NA NA NA NA NA 30649 XM_044318162.1 1006 0 709 21 2751 P26686 1.85e-72 Serine-arginine protein 55 (SRP55) (52 kDa bracketing protein) (B52 protein) (Protein enhancer of deformed) Drosophila melanogaster (Fruit fly) defense response to virus [GO:0051607]; mitotic cell cycle [GO:0000278]; mitotic G1/S transition checkpoint signaling [GO:0044819]; mRNA splicing, via spliceosome [GO:0000398]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of gene expression [GO:0010468]; regulation of mRNA 3'-end processing [GO:0031440]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of transcriptional start site selection at RNA polymerase II promoter [GO:0001178]; RNA splicing [GO:0008380] GO:0000278; GO:0000381; GO:0000398; GO:0000791; GO:0001178; GO:0003723; GO:0003729; GO:0005634; GO:0005700; GO:0008380; GO:0010468; GO:0016607; GO:0031440; GO:0044819; GO:0048024; GO:0051607; GO:0071011; GO:0071013 30650 XM_044316281.1 40 7 35 0 42 Q96AY4 2.62e-71 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30651 XM_044316281.1 40 7 35 0 42 Q96AY4 1.83e-70 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30652 XM_044316281.1 40 7 35 0 42 Q96AY4 4.48e-69 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30653 XM_044316281.1 40 7 35 0 42 Q96AY4 1.82e-66 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30654 XM_044316281.1 40 7 35 0 42 Q96AY4 2.93e-65 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30655 XM_044316281.1 40 7 35 0 42 Q96AY4 2.15e-64 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30656 XM_044316281.1 40 7 35 0 42 Q96AY4 7.71e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30657 XM_044316281.1 40 7 35 0 42 Q96AY4 2.18e-57 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30658 XM_044316281.1 40 7 35 0 42 Q96AY4 6.01e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30659 XM_044316281.1 40 7 35 0 42 Q96AY4 5.05e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30660 XM_044316281.1 40 7 35 0 42 Q96AY4 6.58e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30661 XM_044326524.1 1051 4818 641 866 2582 A7RK30 3.35e-158 Quinone oxidoreductase-like protein 2 homolog (EC 1.-.-.-) Nematostella vectensis (Starlet sea anemone) NA GO:0016491 30662 XM_044323672.1 0 31 6 20 4 B3EX02 3.55e-89 MAM and fibronectin type III domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 30663 XM_044319925.1 199 293 65 109 0 P31230 3.97e-76 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (Multisynthase complex auxiliary component p43) [Cleaved into: Endothelial monocyte-activating polypeptide 2 (EMAP-2) (Endothelial monocyte-activating polypeptide II) (EMAP-II) (Small inducible cytokine subfamily E member 1)] Mus musculus (Mouse) angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell-cell signaling [GO:0007267]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; negative regulation of endothelial cell proliferation [GO:0001937]; positive regulation of glucagon secretion [GO:0070094]; translation [GO:0006412] GO:0000049; GO:0001525; GO:0001937; GO:0005125; GO:0005615; GO:0005634; GO:0005783; GO:0005794; GO:0005829; GO:0006412; GO:0006915; GO:0006954; GO:0007267; GO:0009986; GO:0017101; GO:0042803; GO:0050900; GO:0051020; GO:0070094 30664 XM_044316354.1 15 9 16 3 5 NA NA NA NA NA NA 30665 XM_029333721.2 546 300 323 544 703 Q8BRF7 0 Sec1 family domain-containing protein 1 (Syntaxin-binding protein 1-like 2) Mus musculus (Mouse) cell morphogenesis [GO:0000902]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; negative regulation of autophagosome assembly [GO:1902902]; post-Golgi vesicle-mediated transport [GO:0006892]; regulation of ER to Golgi vesicle-mediated transport [GO:0060628]; regulation of protein transport [GO:0051223]; response to hypoxia [GO:0001666]; response to toxic substance [GO:0009636]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; toxin transport [GO:1901998]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0000902; GO:0001666; GO:0005789; GO:0005798; GO:0005801; GO:0005886; GO:0006886; GO:0006888; GO:0006890; GO:0006892; GO:0009636; GO:0016192; GO:0019905; GO:0032580; GO:0044877; GO:0047485; GO:0051223; GO:0060628; GO:1901998; GO:1902902 30666 XM_044315161.1 18 24 31 73 53 P20664 5.8e-162 DNA primase small subunit (EC 2.7.7.102) (DNA primase 49 kDa subunit) (p49) Mus musculus (Mouse) DNA replication initiation [GO:0006270]; DNA replication, synthesis of RNA primer [GO:0006269] GO:0000287; GO:0003896; GO:0005658; GO:0006269; GO:0006270; GO:0008270; GO:0032553 30667 XR_006393184.1 0 21 4 0 0 NA NA NA NA NA NA 30668 XM_029357015.2 3765 4886 3218 5886 3049 NA NA NA NA NA NA 30669 XM_044309450.1 12 2 28 3 42 NA NA NA NA NA NA 30670 XM_029357117.2 43 58 33 20 251 NA NA NA NA NA NA 30671 XM_044323000.1 1080 859 450 856 1007 NA NA NA NA NA NA 30672 XM_044325542.1 265 248 186 265 454 Q8NBS9 6.28e-70 Thioredoxin domain-containing protein 5 (EC 1.8.4.-) (EC 5.3.4.1) (Endoplasmic reticulum resident protein 46) (ER protein 46) (ERp46) (Thioredoxin-like protein p46) Homo sapiens (Human) negative regulation of apoptotic process [GO:0043066]; protein folding [GO:0006457] GO:0003756; GO:0005576; GO:0005783; GO:0005788; GO:0006457; GO:0015035; GO:0035578; GO:0043066; GO:0043202; GO:0070062 30673 XM_044325542.1 265 248 186 265 454 Q8NBS9 3.3e-52 Thioredoxin domain-containing protein 5 (EC 1.8.4.-) (EC 5.3.4.1) (Endoplasmic reticulum resident protein 46) (ER protein 46) (ERp46) (Thioredoxin-like protein p46) Homo sapiens (Human) negative regulation of apoptotic process [GO:0043066]; protein folding [GO:0006457] GO:0003756; GO:0005576; GO:0005783; GO:0005788; GO:0006457; GO:0015035; GO:0035578; GO:0043066; GO:0043202; GO:0070062 30674 XM_029338176.2 456 90 83 314 409 NA NA NA NA NA NA 30675 XM_029332723.2 30 31 9 0 0 NA NA NA NA NA NA 30676 XM_044314528.1 77 46 97 317 131 NA NA NA NA NA NA 30677 XR_006398111.1 2 21 8 14 4 NA NA NA NA NA NA 30678 XM_029330273.2 0 0 30 19 77 H1AFJ5 1.55e-41 Amiloride-sensitive sodium channel subunit alpha (Alpha-NaCH) (Epithelial Na(+) channel subunit alpha) (Alpha-ENaC) (Nonvoltage-gated sodium channel 1 subunit alpha) (SCNEA) Neoceratodus forsteri (Australian lungfish) (Ceratodus forsteri) sodium ion transmembrane transport [GO:0035725] GO:0001669; GO:0005737; GO:0015280; GO:0016324; GO:0031514; GO:0034706; GO:0035725 30679 XR_006396524.1 73 38 87 56 65 NA NA NA NA NA NA 30680 XM_044326000.1 219 122 115 91 204 Q5M954 7.3e-61 tRNA-splicing endonuclease subunit Sen2 (EC 4.6.1.16) (tRNA-intron endonuclease Sen2) Rattus norvegicus (Rat) mRNA processing [GO:0006397]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]; tRNA-type intron splice site recognition and cleavage [GO:0000379] GO:0000213; GO:0000214; GO:0000379; GO:0003676; GO:0005654; GO:0005730; GO:0005813; GO:0005829; GO:0006388; GO:0006397; GO:0016829 30681 XM_029338998.2 704 356 367 517 598 Q9D2K4 0 IQ domain-containing protein H Mus musculus (Mouse) NA NA 30682 XR_006398009.1 0 4 14 4 37 NA NA NA NA NA NA 30683 XM_029351960.2 187 285 115 389 1117 Q06546 2.35e-59 GA-binding protein alpha chain (GABP subunit alpha) (Nuclear respiratory factor 2 subunit alpha) (Transcription factor E4TF1-60) Homo sapiens (Human) blastocyst formation [GO:0001825]; cell differentiation [GO:0030154]; cellular response to dopamine [GO:1903351]; negative regulation of megakaryocyte differentiation [GO:0045653]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000785; GO:0000976; GO:0000978; GO:0000981; GO:0001228; GO:0001825; GO:0003682; GO:0003700; GO:0005634; GO:0005654; GO:0006357; GO:0010628; GO:0030154; GO:0045653; GO:0045944; GO:1903351; GO:1990837 30684 XM_044317427.1 43 17 80 41 197 NA NA NA NA NA NA 30685 XM_029329197.2 286 156 76 233 298 Q9U6A0 3.46e-59 Sodium/potassium/calcium exchanger Nckx30C (Na(+)/K(+)/Ca(2+)-exchange protein Nckx30C) Drosophila melanogaster (Fruit fly) calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; compound eye development [GO:0048749]; sodium ion transport [GO:0006814] GO:0005262; GO:0005886; GO:0006814; GO:0006816; GO:0006874; GO:0008273; GO:0015293; GO:0016020; GO:0048749; GO:0070588 30686 XM_029330050.2 0 0 10 4 2 NA NA NA NA NA NA 30687 XM_029353466.2 1027 519 550 1121 1311 A0FKN5 2.79e-126 NA NA NA NA 30688 XM_029342440.2 498 231 161 379 371 Q5SPX3 6.25e-35 RING finger protein 215 Mus musculus (Mouse) Golgi to vacuole transport [GO:0006896]; protein targeting to vacuole [GO:0006623]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0005768; GO:0005802; GO:0006511; GO:0006623; GO:0006896; GO:0016020; GO:0017119; GO:0046872; GO:0061630 30689 XM_044325913.1 0 0 0 0 16 NA NA NA NA NA NA 30690 XM_029351240.2 842 1850 1213 939 1126 P60003 3.66e-30 Transcription elongation factor 1 homolog Mus musculus (Mouse) transcription elongation by RNA polymerase II promoter [GO:0006368] GO:0000993; GO:0006368; GO:0008023; GO:0046872 30691 XM_044317860.1 27 0 30 48 40 NA NA NA NA NA NA 30692 XM_029356914.2 73 108 235 230 251 NA NA NA NA NA NA 30693 XM_044327225.1 758 319 282 354 214 Q05084 2.69e-100 Islet cell autoantigen 1 (69 kDa islet cell autoantigen) (ICA69) (Islet cell autoantigen p69) (ICAp69) (p69) Homo sapiens (Human) neurotransmitter transport [GO:0006836]; regulation of transport [GO:0051049] GO:0000139; GO:0005737; GO:0005794; GO:0005829; GO:0006836; GO:0019904; GO:0030667; GO:0030672; GO:0043231; GO:0051049; GO:0140090 30694 XM_044318940.1 26 245 15 51 247 Q58A42 4.66e-73 Protein DD3-3 Dictyostelium discoideum (Social amoeba) NA GO:0016020 30695 XM_044325930.1 625 495 307 438 526 NA NA NA NA NA NA 30696 XM_044311198.1 0 0 0 117 0 NA NA NA NA NA NA 30697 XM_029353120.2 1 0 0 0 39 NA NA NA NA NA NA 30698 XM_029358025.2 1282 1108 989 1405 1112 Q4W5Z4 0 DNA (cytosine-5)-methyltransferase 3A (Dnmt3a) (EC 2.1.1.37) (Cysteine methyltransferase DNMT3A) (EC 2.1.1.-) Gallus gallus (Chicken) chromatin organization [GO:0006325]; DNA methylation [GO:0006306]; regulation of gene expression [GO:0010468]; response to fibroblast growth factor [GO:0071774]; response to heat [GO:0009408] GO:0000791; GO:0001046; GO:0003677; GO:0003886; GO:0005634; GO:0005737; GO:0006306; GO:0006325; GO:0009408; GO:0010468; GO:0016363; GO:0046872; GO:0071774; GO:0106363 30699 XM_044327477.1 39 106 44 109 73 NA NA NA NA NA NA 30700 XM_029329692.2 22 16 41 37 100 Q28G88 8.66e-108 Fez family zinc finger protein 2 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell differentiation [GO:0030154]; nervous system development [GO:0007399] GO:0003677; GO:0005634; GO:0007399; GO:0030154; GO:0046872 30701 XM_044322837.1 31 28 13 17 55 Q7RTR2 3.39e-28 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30702 XM_044322837.1 31 28 13 17 55 Q7RTR2 3.96e-22 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30703 XM_029327143.2 168 305 58 126 79 Q9NRW4 5.59e-51 Dual specificity protein phosphatase 22 (EC 3.1.3.16) (EC 3.1.3.48) (JNK-stimulatory phosphatase-1) (JSP-1) (Low molecular weight dual specificity phosphatase 2) (LMW-DSP2) (Mitogen-activated protein kinase phosphatase x) (MAP kinase phosphatase x) (MKP-x) Homo sapiens (Human) cellular response to epidermal growth factor stimulus [GO:0071364]; dephosphorylation [GO:0016311]; negative regulation of cell migration [GO:0030336]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903996]; negative regulation of T cell activation [GO:0050868]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-tyrosine dephosphorylation [GO:0035335]; positive regulation of JNK cascade [GO:0046330]; regulation of cell population proliferation [GO:0042127]; signal transduction [GO:0007165]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0000122; GO:0002710; GO:0004725; GO:0004726; GO:0005737; GO:0005829; GO:0005886; GO:0007165; GO:0007179; GO:0008138; GO:0016311; GO:0017018; GO:0030336; GO:0031941; GO:0035335; GO:0042127; GO:0046330; GO:0050860; GO:0050868; GO:0051895; GO:0061851; GO:0071364; GO:1903996; GO:1990782 30704 XM_029342901.2 1 1 0 30 19 Q96DM1 7.6e-25 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 30705 XM_029347618.2 171 157 80 0 107 Q8IS64 1.28e-145 Endothelin-converting enzyme homolog (ECE) (EC 3.4.24.-) Locusta migratoria (Migratory locust) proteolysis [GO:0006508] GO:0004175; GO:0004222; GO:0005886; GO:0006508; GO:0008270 30706 XM_029356667.2 2366 1843 1115 1919 1914 Q04519 3.51e-147 Sphingomyelin phosphodiesterase (EC 3.1.4.12) (EC 3.1.4.3) (Acid sphingomyelinase) (ASMase) [Cleaved into: Sphingomyelin phosphodiesterase, processed form] Mus musculus (Mouse) cellular response to calcium ion [GO:0071277]; cellular response to UV [GO:0034644]; ceramide biosynthetic process [GO:0046513]; ceramide metabolic process [GO:0006672]; cholesterol metabolic process [GO:0008203]; negative regulation of MAP kinase activity [GO:0043407]; plasma membrane repair [GO:0001778]; positive regulation of apoptotic process [GO:0043065]; positive regulation of endocytosis [GO:0045807]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of viral entry into host cell [GO:0046598]; response to cocaine [GO:0042220]; response to interleukin-1 [GO:0070555]; response to ionizing radiation [GO:0010212]; response to tumor necrosis factor [GO:0034612]; response to type I interferon [GO:0034340]; response to virus [GO:0009615]; response to xenobiotic stimulus [GO:0009410]; sphingomyelin catabolic process [GO:0006685]; termination of signal transduction [GO:0023021]; viral entry into host cell [GO:0046718]; wound healing [GO:0042060] GO:0001778; GO:0004767; GO:0005615; GO:0005764; GO:0005768; GO:0005811; GO:0005886; GO:0006672; GO:0006685; GO:0008081; GO:0008203; GO:0008270; GO:0009410; GO:0009615; GO:0010212; GO:0016798; GO:0023021; GO:0034340; GO:0034480; GO:0034612; GO:0034644; GO:0035307; GO:0036019; GO:0042060; GO:0042220; GO:0042599; GO:0043065; GO:0043407; GO:0045807; GO:0046513; GO:0046598; GO:0046718; GO:0061750; GO:0070555; GO:0071277 30707 XR_006392018.1 0 0 0 7 0 NA NA NA NA NA NA 30708 XM_029326823.2 494 437 266 1000 1019 B8EIZ7 3.91e-149 NA NA NA NA 30709 XM_044318546.1 880 477 482 825 840 P35445 2.5e-135 Cartilage oligomeric matrix protein (COMP) Bos taurus (Bovine) apoptotic process [GO:0006915]; artery morphogenesis [GO:0048844]; BMP signaling pathway [GO:0030509]; bone mineralization [GO:0030282]; cartilage homeostasis [GO:1990079]; chondrocyte development [GO:0002063]; chondrocyte proliferation [GO:0035988]; collagen fibril organization [GO:0030199]; growth plate cartilage development [GO:0003417]; limb development [GO:0060173]; multicellular organism aging [GO:0010259]; multicellular organism growth [GO:0035264]; musculoskeletal movement [GO:0050881]; negative regulation of apoptotic process [GO:0043066]; negative regulation of hemostasis [GO:1900047]; platelet aggregation [GO:0070527]; positive regulation of chondrocyte proliferation [GO:1902732]; protein homooligomerization [GO:0051260]; protein processing [GO:0016485]; protein secretion [GO:0009306]; regulation of bone mineralization [GO:0030500]; regulation of gene expression [GO:0010468]; response to unfolded protein [GO:0006986]; skin development [GO:0043588]; tendon development [GO:0035989]; vascular associated smooth muscle cell development [GO:0097084]; vascular associated smooth muscle contraction [GO:0014829] GO:0002020; GO:0002063; GO:0003417; GO:0005178; GO:0005509; GO:0005518; GO:0005576; GO:0005615; GO:0006915; GO:0006986; GO:0008201; GO:0009306; GO:0010259; GO:0010468; GO:0014829; GO:0016485; GO:0030199; GO:0030282; GO:0030500; GO:0030509; GO:0032991; GO:0035264; GO:0035988; GO:0035989; GO:0036122; GO:0043066; GO:0043395; GO:0043588; GO:0048844; GO:0050881; GO:0051260; GO:0060173; GO:0062023; GO:0070527; GO:0097084; GO:1900047; GO:1902732; GO:1990079 30710 XM_044317941.1 313 0 0 190 19 NA NA NA NA NA NA 30711 XM_044314162.1 8 17 0 3 9 NA NA NA NA NA NA 30712 XM_029355436.2 37 2 5 9 8 O88350 4.39e-54 Serine hydrolase RBBP9 (EC 3.-.-.-) (B5T-overexpressed gene protein) (Protein BOG) (Retinoblastoma-binding protein 9) (RBBP-9) Rattus norvegicus (Rat) positive regulation of gene expression [GO:0010628]; regulation of cell population proliferation [GO:0042127]; response to nematode [GO:0009624]; type II pneumocyte differentiation [GO:0060510] GO:0005654; GO:0009624; GO:0010628; GO:0016787; GO:0042127; GO:0060510 30713 XM_044318012.1 29 18 4 0 3 NA NA NA NA NA NA 30714 XM_029357140.2 65 28 88 78 52 NA NA NA NA NA NA 30715 XM_029327373.2 69 21 76 47 54 NA NA NA NA NA NA 30716 XM_029358571.2 305 275 337 260 156 Q9R088 2.58e-62 Thymidine kinase 2, mitochondrial (EC 2.7.1.21) (2'-deoxyuridine kinase TK2) (EC 2.7.1.74) (Deoxycytidine kinase TK2) (EC 2.7.1.-) (Mt-TK) Mus musculus (Mouse) deoxycytidine metabolic process [GO:0046092]; deoxyribonucleotide metabolic process [GO:0009262]; DNA biosynthetic process [GO:0071897]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA replication [GO:0006264]; phosphorylation [GO:0016310]; thymidine metabolic process [GO:0046104] GO:0004137; GO:0004797; GO:0005524; GO:0005737; GO:0005739; GO:0005743; GO:0006264; GO:0009262; GO:0016310; GO:0019136; GO:0032042; GO:0046092; GO:0046104; GO:0071897 30717 XM_029356144.2 91 0 21 0 32 NA NA NA NA NA NA 30718 XM_029331866.2 927 529 452 724 659 A7SVT1 0 Protein adenylyltransferase Fic (EC 2.7.7.108) (De-AMPylase Fic) (EC 3.1.4.-) Nematostella vectensis (Starlet sea anemone) NA GO:0005524; GO:0016020; GO:0016787; GO:0070733 30719 XM_044310943.1 59 240 74 129 8 Q5DU56 1.6e-23 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30720 XM_044310943.1 59 240 74 129 8 Q5DU56 9.38e-22 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30721 XM_029345680.2 0 135 0 332 44 Q9C0D7 2.7e-86 Probable ribonuclease ZC3H12C (EC 3.1.-.-) (MCP-induced protein 3) (Zinc finger CCCH domain-containing protein 12C) Homo sapiens (Human) RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502] GO:0003729; GO:0004521; GO:0005634; GO:0036464; GO:0046872; GO:0090502 30722 XR_003823950.2 159 50 63 106 89 NA NA NA NA NA NA 30723 XM_044324817.1 117 6 235 20 1043 NA NA NA NA NA NA 30724 XM_044311636.1 1 0 2 6 0 NA NA NA NA NA NA 30725 XM_044322899.1 3412 2602 1999 3640 2721 Q9BWQ8 2.46e-60 Protein lifeguard 2 (Fas apoptotic inhibitory molecule 2) (Neural membrane protein 35) (Transmembrane BAX inhibitor motif-containing protein 2) Homo sapiens (Human) apoptotic signaling pathway [GO:0097190]; cerebellar granular layer development [GO:0021681]; cerebellar Purkinje cell differentiation [GO:0021702]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum development [GO:0021549]; negative regulation of apoptotic process [GO:0043066]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of neuron apoptotic process [GO:0043524]; neuron apoptotic process [GO:0051402]; regulation of neuron apoptotic process [GO:0043523]; response to ischemia [GO:0002931] GO:0002931; GO:0005783; GO:0005794; GO:0016020; GO:0021549; GO:0021680; GO:0021681; GO:0021702; GO:0043066; GO:0043523; GO:0043524; GO:0045121; GO:0045211; GO:0051402; GO:0097190; GO:1902042; GO:2001234 30726 XR_006396793.1 4 1 1 24 5 NA NA NA NA NA NA 30727 XM_029356565.2 255 380 185 482 500 A7RRJ0 0 Flap endonuclease 1 (FEN-1) (EC 3.1.-.-) (Flap structure-specific endonuclease 1) Nematostella vectensis (Starlet sea anemone) base-excision repair [GO:0006284]; DNA replication, removal of RNA primer [GO:0043137] GO:0000287; GO:0003677; GO:0004523; GO:0005634; GO:0005654; GO:0005730; GO:0005739; GO:0006284; GO:0008409; GO:0017108; GO:0030145; GO:0043137 30728 XM_029327494.2 97 122 5 29 49 NA NA NA NA NA NA 30729 XM_029335401.2 194 77 92 106 100 O82201 8.94e-67 AP-4 complex subunit sigma (AP-4 adaptor complex subunit sigma) (Adaptor-related protein complex 4 subunit sigma) (Sigma subunit of AP-4) (Sigma4-adaptin) Arabidopsis thaliana (Mouse-ear cress) protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] GO:0005802; GO:0005905; GO:0015031; GO:0016192; GO:0030124; GO:0043231 30730 XM_044323035.1 0 5 0 0 63 NA NA NA NA NA NA 30731 XM_029328442.2 146 0 134 5 173 NA NA NA NA NA NA 30732 XM_044320547.1 53 68 57 80 69 NA NA NA NA NA NA 30733 XM_044309671.1 266 95 297 136 705 NA NA NA NA NA NA 30734 XM_029329952.2 0 0 43 0 92 Q16445 1.06e-57 Gamma-aminobutyric acid receptor subunit alpha-6 (GABA(A) receptor subunit alpha-6) Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid signaling pathway [GO:0007214]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; regulation of postsynaptic membrane potential [GO:0060078]; signal transduction [GO:0007165]; synaptic transmission, GABAergic [GO:0051932] GO:0004890; GO:0005231; GO:0005237; GO:0005886; GO:0007165; GO:0007214; GO:0007268; GO:0008503; GO:0022851; GO:0030594; GO:0032590; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051932; GO:0060078; GO:0098794; GO:0099192; GO:1902476; GO:1902711; GO:1904315 30735 XM_029357127.2 36 27 1 11 17 NA NA NA NA NA NA 30736 XM_029341642.2 9872 8463 1659 3701 1921 A8WG21 3.34e-23 Sorting nexin-10B Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; intracellular protein transport [GO:0006886]; vesicle organization [GO:0016050] GO:0005768; GO:0006886; GO:0010008; GO:0016050; GO:0060271; GO:1901981 30737 XM_029352596.2 460 453 218 549 523 Q8N8E3 0 Centrosomal protein of 112 kDa (Cep112) (Coiled-coil domain-containing protein 46) Homo sapiens (Human) receptor localization to synapse [GO:0097120] GO:0005737; GO:0005813; GO:0005886; GO:0060077; GO:0097120 30738 XM_029345390.2 3008 1315 1612 1268 642 P28562 8.43e-83 Dual specificity protein phosphatase 1 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity protein phosphatase hVH1) (Mitogen-activated protein kinase phosphatase 1) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase CL100) Homo sapiens (Human) cell cycle [GO:0007049]; cellular response to chemokine [GO:1990869]; endoderm formation [GO:0001706]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of meiotic cell cycle [GO:0051447]; negative regulation of monocyte chemotaxis [GO:0090027]; negative regulation of p38MAPK cascade [GO:1903753]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; peptidyl-tyrosine dephosphorylation [GO:0035335]; regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090266] GO:0001706; GO:0004721; GO:0004722; GO:0004725; GO:0005634; GO:0005737; GO:0007049; GO:0007162; GO:0008138; GO:0008285; GO:0008330; GO:0017017; GO:0017018; GO:0035335; GO:0035970; GO:0043407; GO:0043409; GO:0051019; GO:0051447; GO:0070262; GO:0090027; GO:0090266; GO:1903753; GO:1990869 30739 XM_029341837.2 126 94 117 102 174 NA NA NA NA NA NA 30740 XM_044314630.1 67 10 66 33 77 NA NA NA NA NA NA 30741 XM_029336530.2 179 86 63 112 160 NA NA NA NA NA NA 30742 XM_029356201.2 0 0 134 57 494 Q6MG12 3.96e-24 Uncharacterized protein C6orf136 homolog Rattus norvegicus (Rat) NA NA 30743 XM_029328647.2 514 699 421 638 429 Q62687 4.59e-154 Sodium-dependent neutral amino acid transporter B(0)AT3 (Renal osmotic stress-induced Na-Cl organic solute cotransporter) (ROSIT) (Sodium- and chloride-dependent transporter XTRP2) (Solute carrier family 6 member 18) (System B(0) neutral amino acid transporter AT3) Rattus norvegicus (Rat) amino acid transmembrane transport [GO:0003333]; hyperosmotic response [GO:0006972]; neurotransmitter transport [GO:0006836]; neutral amino acid transport [GO:0015804]; renal amino acid absorption [GO:1990297]; response to osmotic stress [GO:0006970]; sodium ion transmembrane transport [GO:0035725] GO:0003333; GO:0005886; GO:0006836; GO:0006970; GO:0006972; GO:0015175; GO:0015804; GO:0016324; GO:0031526; GO:0035725; GO:0140931; GO:1990297 30744 XM_044315005.1 118 7 0 19 3 NA NA NA NA NA NA 30745 XM_044310866.1 0 5 0 122 0 NA NA NA NA NA NA 30746 XM_029346538.2 0 0 0 26 10 P32297 2.64e-92 Neuronal acetylcholine receptor subunit alpha-3 Homo sapiens (Human) acetylcholine receptor signaling pathway [GO:0095500]; activation of transmembrane receptor protein tyrosine kinase activity [GO:0007171]; behavioral response to nicotine [GO:0035095]; chemical synaptic transmission [GO:0007268]; excitatory postsynaptic potential [GO:0060079]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; locomotory behavior [GO:0007626]; membrane depolarization [GO:0051899]; nervous system development [GO:0007399]; nervous system process [GO:0050877]; regulation of acetylcholine secretion, neurotransmission [GO:0014056]; regulation of dendrite morphogenesis [GO:0048814]; regulation of membrane potential [GO:0042391]; regulation of smooth muscle contraction [GO:0006940]; response to acetylcholine [GO:1905144]; signal transduction [GO:0007165]; synaptic transmission involved in micturition [GO:0060084]; synaptic transmission, cholinergic [GO:0007271] GO:0005231; GO:0005886; GO:0005892; GO:0006811; GO:0006940; GO:0007165; GO:0007171; GO:0007268; GO:0007271; GO:0007399; GO:0007626; GO:0014056; GO:0014069; GO:0015276; GO:0015464; GO:0016020; GO:0016607; GO:0022848; GO:0030425; GO:0030594; GO:0034220; GO:0035095; GO:0042166; GO:0042391; GO:0043005; GO:0043025; GO:0044853; GO:0045202; GO:0045211; GO:0048814; GO:0050877; GO:0051899; GO:0060079; GO:0060084; GO:0095500; GO:1904315; GO:1905144 30747 XR_006397162.1 42 147 71 211 39 NA NA NA NA NA NA 30748 XM_029341396.2 352 256 240 317 432 O60140 5.89e-40 Uncharacterized protein C18H10.09 Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0005634; GO:0005737; GO:0006511; GO:0008270; GO:0016567; GO:0061630 30749 XM_044322212.1 110 281 194 98 0 NA NA NA NA NA NA 30750 XM_029352682.2 482 902 190 261 341 P09013 2.93e-24 Homeobox protein Hox-B5b (Homeobox protein Zf-54) (Hox-B5-like) Danio rerio (Zebrafish) (Brachydanio rerio) anterior/posterior pattern specification [GO:0009952]; brain development [GO:0007420]; cardioblast differentiation [GO:0010002]; cell fate specification [GO:0001708]; heart development [GO:0007507]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0001708; GO:0005634; GO:0006357; GO:0007420; GO:0007507; GO:0009952; GO:0010002 30751 XM_044311837.1 0 0 12 2 26 NA NA NA NA NA NA 30752 XM_044327772.1 43 38 24 6 20 NA NA NA NA NA NA 30753 XM_029336410.2 412 1106 1169 933 2176 NA NA NA NA NA NA 30754 XM_029331444.2 1604 2889 1750 1580 1551 Q6P342 1.4e-46 Diacylglycerol O-acyltransferase 2 (EC 2.3.1.20) (Acyl-CoA retinol O-fatty-acyltransferase) (ARAT) (Retinol O-fatty-acyltransferase) (EC 2.3.1.76) (Diglyceride acyltransferase 2) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) diacylglycerol biosynthetic process [GO:0006651]; glycerol metabolic process [GO:0006071]; monoacylglycerol biosynthetic process [GO:0006640]; triglyceride biosynthetic process [GO:0019432] GO:0004144; GO:0005789; GO:0005811; GO:0006071; GO:0006640; GO:0006651; GO:0019432; GO:0050252; GO:1990578 30755 XM_029343548.2 25 9 4 0 96 NA NA NA NA NA NA 30756 XM_029334688.2 131 102 113 222 160 Q8RWL6 6.31e-27 Serine/threonine-protein kinase STY17 (EC 2.7.11.1) (Serine/threonine/tyrosine-protein kinase 17) Arabidopsis thaliana (Mouse-ear cress) chloroplast organization [GO:0009658]; protein phosphorylation [GO:0006468] GO:0004674; GO:0004712; GO:0005524; GO:0005829; GO:0006468; GO:0009658; GO:0106310 30757 XM_044308609.1 13 57 72 24 87 NA NA NA NA NA NA 30758 XM_029326084.2 35 28 7 7 61 Q9UHR5 1.2e-27 SAP30-binding protein (Transcriptional regulator protein HCNGP) Homo sapiens (Human) modulation by host of symbiont transcription [GO:0052472]; positive regulation of histone deacetylation [GO:0031065]; regulation of DNA-templated transcription [GO:0006355]; response to virus [GO:0009615] GO:0005634; GO:0005654; GO:0006355; GO:0009615; GO:0031065; GO:0045111; GO:0052472 30759 XM_044313147.1 9 22 27 62 27 Q5ZI69 4.4e-33 39S ribosomal protein L37, mitochondrial (L37mt) (MRP-L37) Gallus gallus (Chicken) translation [GO:0006412] GO:0003735; GO:0005739; GO:0005743; GO:0005762; GO:0006412 30760 XR_006393238.1 36 135 229 282 157 O70244 2.71e-47 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 30761 XR_006393238.1 36 135 229 282 157 O70244 3.99e-43 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 30762 XR_006393238.1 36 135 229 282 157 O70244 3.52e-41 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 30763 XR_006393238.1 36 135 229 282 157 O70244 1.26e-40 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 30764 XR_006393238.1 36 135 229 282 157 O70244 1.39e-39 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 30765 XR_006393238.1 36 135 229 282 157 O70244 4.84e-37 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 30766 XR_006393238.1 36 135 229 282 157 O70244 2.68e-36 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 30767 XR_006393238.1 36 135 229 282 157 O70244 8.05e-30 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 30768 XR_006393238.1 36 135 229 282 157 O70244 2.61e-29 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 30769 XR_006393238.1 36 135 229 282 157 O70244 5.04e-29 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 30770 XR_006393238.1 36 135 229 282 157 O70244 2.58e-26 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 30771 XR_006393238.1 36 135 229 282 157 O70244 2.57e-25 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 30772 XR_006393238.1 36 135 229 282 157 O70244 1.37e-24 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 30773 XR_006393238.1 36 135 229 282 157 O70244 2.33e-23 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 30774 XR_006393238.1 36 135 229 282 157 O70244 7.12e-22 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 30775 XR_003824861.2 18 8 7 11 66 NA NA NA NA NA NA 30776 XM_029340006.2 3290 3016 2481 3711 2523 NA NA NA NA NA NA 30777 XM_029343491.2 14 1 13 18 37 NA NA NA NA NA NA 30778 XM_044317784.1 7 6 17 5 10 NA NA NA NA NA NA 30779 XM_044312957.1 60 29 39 132 17 Q8K3Z0 7.95e-33 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 30780 XM_044327082.1 32 29 1 14 0 NA NA NA NA NA NA 30781 XM_029352470.2 92 9 48 143 89 NA NA NA NA NA NA 30782 XM_044324744.1 263 207 119 146 82 Q8VBV3 1.19e-123 Exosome complex component RRP4 (Exosome component 2) (Ribosomal RNA-processing protein 4) Mus musculus (Mouse) CUT catabolic process [GO:0071034]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; positive regulation of cell growth [GO:0030307]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]; U4 snRNA 3'-end processing [GO:0034475] GO:0000176; GO:0000177; GO:0000178; GO:0000467; GO:0003723; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0006396; GO:0006401; GO:0030307; GO:0034427; GO:0034475; GO:0043928; GO:0071034; GO:0071035; GO:0071038; GO:0071051; GO:0101019 30783 XM_029346542.2 107 282 154 179 157 Q9EQS3 5.56e-28 c-Myc-binding protein (Associate of Myc 1) (AMY-1) Mus musculus (Mouse) regulation of DNA-templated transcription [GO:0006355] GO:0003713; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0006355 30784 XM_044320463.1 4192 3201 3234 6683 4194 Q3KQW7 2.5e-27 LIM and calponin homology domains-containing protein 1 Xenopus laevis (African clawed frog) actomyosin structure organization [GO:0031032]; negative regulation of cell migration [GO:0030336]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of stress fiber assembly [GO:0051496]; regulation of focal adhesion assembly [GO:0051893] GO:0001725; GO:0001934; GO:0003779; GO:0005737; GO:0030336; GO:0031032; GO:0046872; GO:0051496; GO:0051893 30785 XM_029338330.2 90 9 15 23 56 NA NA NA NA NA NA 30786 XM_029345800.2 335 202 247 236 402 Q0DXS3 9.05e-137 Probable RNA-dependent RNA polymerase 1 (OsRDR1) (EC 2.7.7.48) Oryza sativa subsp. japonica (Rice) positive regulation of post-transcriptional gene silencing [GO:0060148]; response to salicylic acid [GO:0009751]; response to virus [GO:0009615]; siRNA processing [GO:0030422]; wax biosynthetic process [GO:0010025] GO:0003723; GO:0003968; GO:0009615; GO:0009751; GO:0010025; GO:0030422; GO:0031380; GO:0060148 30787 XM_029331349.2 11 178 11 11 77 NA NA NA NA NA NA 30788 XR_003824277.2 36 1 36 21 136 NA NA NA NA NA NA 30789 XM_044322700.1 25 2 0 10 11 Q9DGD1 3.57e-61 Alpha-1,6-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase (EC 2.4.1.201) (N-acetylglucosaminyltransferase VI) (GnT-VI) Gallus gallus (Chicken) protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0046872; GO:0047253 30790 XR_003825238.2 241 49 146 76 188 NA NA NA NA NA NA 30791 XM_029354837.2 94 32 97 100 100 Q20191 5.77e-41 Zinc metalloproteinase nas-13 (EC 3.4.24.-) (Nematode astacin 13) Caenorhabditis elegans proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0006508; GO:0008270 30792 XM_044308397.1 4337 3601 2135 2489 2603 P54357 3.1e-37 Myosin-2 essential light chain (Myosin II essential light chain) (Non-muscle myosin essential light chain) Drosophila melanogaster (Fruit fly) actin filament-based movement [GO:0030048] GO:0005509; GO:0005829; GO:0016460; GO:0017022; GO:0030048; GO:0031475; GO:0031476; GO:0031477; GO:0032036 30793 XM_044323575.1 0 0 9 24 16 NA NA NA NA NA NA 30794 XM_029356240.2 754 712 452 675 523 P23640 1.99e-94 Ras-related protein Rab-27A (Rab-27) (EC 3.6.5.2) (GTP-binding protein Ram) (Ram p25) Rattus norvegicus (Rat) antigen processing and presentation [GO:0019882]; blood coagulation [GO:0007596]; complement-dependent cytotoxicity [GO:0097278]; cytotoxic T cell degranulation [GO:0043316]; exocytosis [GO:0006887]; exosomal secretion [GO:1990182]; melanocyte differentiation [GO:0030318]; melanosome localization [GO:0032400]; melanosome transport [GO:0032402]; multivesicular body organization [GO:0036257]; multivesicular body sorting pathway [GO:0071985]; natural killer cell degranulation [GO:0043320]; pigment granule localization [GO:0051875]; pigment granule transport [GO:0051904]; pigmentation [GO:0043473]; positive regulation of constitutive secretory pathway [GO:1903435]; positive regulation of exocytosis [GO:0045921]; positive regulation of gene expression [GO:0010628]; positive regulation of phagocytosis [GO:0050766]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of regulated secretory pathway [GO:1903307]; protein targeting [GO:0006605]; vesicle-mediated transport [GO:0016192] GO:0001750; GO:0003924; GO:0003925; GO:0005525; GO:0005764; GO:0005770; GO:0005794; GO:0006605; GO:0006887; GO:0007596; GO:0010628; GO:0016192; GO:0016324; GO:0019003; GO:0019882; GO:0019904; GO:0030141; GO:0030318; GO:0030425; GO:0030667; GO:0031489; GO:0032400; GO:0032402; GO:0032585; GO:0033093; GO:0036257; GO:0042470; GO:0043316; GO:0043320; GO:0043473; GO:0045921; GO:0050766; GO:0051875; GO:0051904; GO:0070382; GO:0071985; GO:0097278; GO:1903307; GO:1903428; GO:1903435; GO:1990182 30795 XM_029349502.2 14 11 8 13 2 NA NA NA NA NA NA 30796 XM_029350374.2 99 25 42 52 0 NA NA NA NA NA NA 30797 XM_044324741.1 146 48 99 130 243 Q9UBM8 1.23e-22 Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C (EC 2.4.1.145) (N-acetylglucosaminyltransferase IV homolog) (hGnT-IV-H) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVc) (GlcNAc-T IVc) (GnT-IVc) (N-acetylglucosaminyltransferase IVc) (UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVc) Homo sapiens (Human) protein N-linked glycosylation [GO:0006487]; viral protein processing [GO:0019082] GO:0000139; GO:0006487; GO:0008375; GO:0008454; GO:0019082; GO:0046872 30798 XM_029355301.2 5 10 3 5 6 Q5RDZ2 3.29e-87 Lambda-crystallin homolog (EC 1.1.1.45) (L-gulonate 3-dehydrogenase) (Gul3DH) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) fatty acid metabolic process [GO:0006631]; glucuronate catabolic process to xylulose 5-phosphate [GO:0019640] GO:0005829; GO:0006631; GO:0019640; GO:0042803; GO:0050104; GO:0070403 30799 XM_044311407.1 0 0 0 0 10 NA NA NA NA NA NA 30800 XM_044317300.1 8 0 2 0 1 Q8K2J9 5.49e-62 BTB/POZ domain-containing protein 6 Mus musculus (Mouse) neurogenesis [GO:0022008] GO:0005829; GO:0022008 30801 XM_044326174.1 0 33 15 34 41 NA NA NA NA NA NA 30802 XM_029327228.2 5 189 1 247 168 Q6ZQR2 5.62e-33 Cilia- and flagella-associated protein 77 Homo sapiens (Human) NA GO:0005929 30803 XM_029328601.2 162 114 170 1049 345 E7FAM5 0 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 30804 XM_044309511.1 90 13 101 43 71 NA NA NA NA NA NA 30805 XM_029352785.2 408 318 501 410 430 Q95SX7 6.69e-37 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 30806 XM_044319133.1 267 0 663 385 568 NA NA NA NA NA NA 30807 XR_006395852.1 39 88 128 56 74 NA NA NA NA NA NA 30808 XM_029335793.2 112 0 0 118 184 NA NA NA NA NA NA 30809 XR_003828295.2 21 20 26 22 60 NA NA NA NA NA NA 30810 XR_006395052.1 3 0 7 0 0 NA NA NA NA NA NA 30811 XM_044316172.1 0 111 42 41 20 NA NA NA NA NA NA 30812 XM_044316115.1 25 12 8 13 2 NA NA NA NA NA NA 30813 XM_029323480.2 9 14 15 6 13 Q99315 1.27e-61 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 30814 XR_006394389.1 3 6 0 0 0 NA NA NA NA NA NA 30815 XM_044314081.1 1150 779 640 774 449 O76387 1.12e-28 Probable peptidyl-tRNA hydrolase 2 (PTH 2) (EC 3.1.1.29) Caenorhabditis elegans NA GO:0004045; GO:0005739; GO:0005829 30816 XM_044325565.1 1293 632 456 1278 1069 P41216 0 Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3) (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain acyl-CoA synthetase 1) (LACS 1) (Phytanate--CoA ligase) (EC 6.2.1.24) Mus musculus (Mouse) adiponectin-activated signaling pathway [GO:0033211]; fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; lipid biosynthetic process [GO:0008610]; long-chain fatty acid import into cell [GO:0044539]; long-chain fatty acid metabolic process [GO:0001676]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of long-chain fatty acid import across plasma membrane [GO:0010747]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; response to nutrient [GO:0007584]; response to oleic acid [GO:0034201]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; triglyceride biosynthetic process [GO:0019432]; very long-chain fatty acid metabolic process [GO:0000038]; xenobiotic catabolic process [GO:0042178] GO:0000038; GO:0001676; GO:0004467; GO:0005524; GO:0005739; GO:0005741; GO:0005778; GO:0005783; GO:0005789; GO:0005886; GO:0006631; GO:0007584; GO:0008610; GO:0010033; GO:0010747; GO:0014070; GO:0015908; GO:0016020; GO:0019432; GO:0033211; GO:0034201; GO:0035338; GO:0042178; GO:0044539; GO:0047676; GO:0050197; GO:0070251; GO:0071902; GO:0090434; GO:0120162 30817 XM_029350550.2 943 1015 1067 2454 803 O95786 8.4e-125 Antiviral innate immune response receptor RIG-I (ATP-dependent RNA helicase DDX58) (EC 3.6.4.13) (DEAD box protein 58) (RIG-I-like receptor 1) (RLR-1) (RNA sensor RIG-I) (Retinoic acid-inducible gene 1 protein) (RIG-1) (Retinoic acid-inducible gene I protein) (RIG-I) Homo sapiens (Human) antiviral innate immune response [GO:0140374]; cellular response to exogenous dsRNA [GO:0071360]; cytosolic pattern recognition receptor signaling pathway [GO:0002753]; defense response to virus [GO:0051607]; detection of virus [GO:0009597]; gene expression [GO:0010467]; innate immune response [GO:0045087]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of gene expression [GO:0010628]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of myeloid dendritic cell cytokine production [GO:0002735]; positive regulation of response to cytokine stimulus [GO:0060760]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell migration [GO:0030334]; regulation of type III interferon production [GO:0034344]; response to exogenous dsRNA [GO:0043330]; response to virus [GO:0009615]; RIG-I signaling pathway [GO:0039529] GO:0002230; GO:0002735; GO:0002753; GO:0003690; GO:0003724; GO:0003725; GO:0003727; GO:0005524; GO:0005525; GO:0005737; GO:0005829; GO:0005923; GO:0008270; GO:0009597; GO:0009615; GO:0010467; GO:0010628; GO:0015629; GO:0016887; GO:0030334; GO:0031625; GO:0032587; GO:0032725; GO:0032727; GO:0032728; GO:0032755; GO:0032757; GO:0032760; GO:0034344; GO:0039529; GO:0042802; GO:0043330; GO:0045087; GO:0045944; GO:0051091; GO:0051607; GO:0060760; GO:0071360; GO:0140374; GO:1990904 30818 XM_044314859.1 0 0 2 0 7 NA NA NA NA NA NA 30819 XM_029340102.2 2 13 12 0 7 NA NA NA NA NA NA 30820 XM_029355545.2 2244 1737 1119 2731 1901 Q9I9M5 0 Frizzled-1 (Fz-1) (Xfz1) Xenopus laevis (African clawed frog) Wnt signaling pathway [GO:0016055] GO:0004930; GO:0005886; GO:0016055 30821 XM_029346108.2 834 955 754 845 501 Q9H0R1 8.25e-88 AP-5 complex subunit mu-1 (Adaptor-related protein complex 5 subunit mu-1) (Mu5) (Mu-2-related death-inducing protein) (MuD) (Putative HIV-1 infection-related protein) Homo sapiens (Human) endosomal transport [GO:0016197]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] GO:0005764; GO:0005765; GO:0005770; GO:0005829; GO:0015031; GO:0016020; GO:0016192; GO:0016197; GO:0030119; GO:0031902; GO:0044599 30822 XM_029330474.2 0 0 0 8 4 NA NA NA NA NA NA 30823 XM_029343297.2 0 49 0 0 63 Q15329 1.11e-98 Transcription factor E2F5 (E2F-5) Homo sapiens (Human) cell projection organization [GO:0030030]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000785; GO:0000978; GO:0000981; GO:0001216; GO:0001650; GO:0003700; GO:0005654; GO:0005730; GO:0006357; GO:0030030; GO:0043231; GO:0046983; GO:0090575 30824 XM_029333696.2 23 9 0 30 34 O15973 5.33e-30 Rhodopsin, GQ-coupled (GQ-rhodopsin) Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis) phototransduction [GO:0007602]; visual perception [GO:0007601] GO:0004930; GO:0005886; GO:0007601; GO:0007602; GO:0009881 30825 XR_003823114.2 13 13 0 0 0 NA NA NA NA NA NA 30826 XR_006398027.1 141 76 140 72 121 A6QPM3 5.17e-43 Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.361) (PR domain zinc finger protein 6) (PR domain-containing protein 6) Bos taurus (Bovine) chromatin organization [GO:0006325]; histone methylation [GO:0016571]; regulation of gene expression [GO:0010468] GO:0005634; GO:0006325; GO:0010468; GO:0016571; GO:0046872; GO:0140944 30827 XR_006398027.1 141 76 140 72 121 A6QPM3 5.12e-37 Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.361) (PR domain zinc finger protein 6) (PR domain-containing protein 6) Bos taurus (Bovine) chromatin organization [GO:0006325]; histone methylation [GO:0016571]; regulation of gene expression [GO:0010468] GO:0005634; GO:0006325; GO:0010468; GO:0016571; GO:0046872; GO:0140944 30828 XM_044313348.1 68 5 15 33 44 NA NA NA NA NA NA 30829 XM_029330171.2 0 28 0 0 0 A4UTP7 3.49e-63 Myocyte-specific enhancer factor 2C Sus scrofa (Pig) B cell homeostasis [GO:0001782]; B cell proliferation [GO:0042100]; B cell receptor signaling pathway [GO:0050853]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cardiac ventricle formation [GO:0003211]; cardiocyte differentiation [GO:0035051]; cellular response to calcium ion [GO:0071277]; cellular response to fluid shear stress [GO:0071498]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cellular response to trichostatin A [GO:0035984]; cellular response to xenobiotic stimulus [GO:0071466]; chondrocyte differentiation [GO:0002062]; endochondral ossification [GO:0001958]; epithelial cell proliferation involved in renal tubule morphogenesis [GO:2001013]; germinal center formation [GO:0002467]; glomerulus morphogenesis [GO:0072102]; heart development [GO:0007507]; heart looping [GO:0001947]; humoral immune response [GO:0006959]; learning or memory [GO:0007611]; MAPK cascade [GO:0000165]; melanocyte differentiation [GO:0030318]; muscle cell fate determination [GO:0007521]; negative regulation of gene expression [GO:0010629]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of ossification [GO:0030279]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nephron tubule epithelial cell differentiation [GO:0072160]; neural crest cell differentiation [GO:0014033]; neuron development [GO:0048666]; neuron differentiation [GO:0030182]; osteoblast differentiation [GO:0001649]; outflow tract morphogenesis [GO:0003151]; platelet formation [GO:0030220]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of behavioral fear response [GO:2000987]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cardiac muscle cell differentiation [GO:2000727]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of macrophage apoptotic process [GO:2000111]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of skeletal muscle cell differentiation [GO:2001016]; positive regulation of skeletal muscle tissue development [GO:0048643]; positive regulation of transcription by RNA polymerase II [GO:0045944]; primary heart field specification [GO:0003138]; regulation of germinal center formation [GO:0002634]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of synaptic activity [GO:0060025]; regulation of transcription by RNA polymerase II [GO:0006357]; renal tubule morphogenesis [GO:0061333]; secondary heart field specification [GO:0003139]; sinoatrial valve morphogenesis [GO:0003185]; skeletal muscle tissue development [GO:0007519]; smooth muscle cell differentiation [GO:0051145]; ventricular cardiac muscle cell differentiation [GO:0055012] GO:0000122; GO:0000165; GO:0000976; GO:0000977; GO:0000978; GO:0000981; GO:0001228; GO:0001568; GO:0001649; GO:0001782; GO:0001947; GO:0001958; GO:0001974; GO:0002062; GO:0002467; GO:0002634; GO:0003138; GO:0003139; GO:0003151; GO:0003185; GO:0003211; GO:0003677; GO:0003700; GO:0005634; GO:0005737; GO:0006357; GO:0006959; GO:0007507; GO:0007519; GO:0007521; GO:0007611; GO:0010628; GO:0010629; GO:0010694; GO:0014033; GO:0016528; GO:0016607; GO:0030182; GO:0030220; GO:0030279; GO:0030318; GO:0030501; GO:0030890; GO:0032991; GO:0035051; GO:0035984; GO:0042100; GO:0043524; GO:0045652; GO:0045663; GO:0045666; GO:0045669; GO:0045893; GO:0045944; GO:0046983; GO:0048643; GO:0048666; GO:0050853; GO:0051145; GO:0055012; GO:0060025; GO:0060045; GO:0061333; GO:0071222; GO:0071277; GO:0071374; GO:0071466; GO:0071498; GO:0071560; GO:0072102; GO:0072160; GO:2000111; GO:2000727; GO:2000987; GO:2001013; GO:2001016 30830 XM_029339575.2 0 0 1 2 12 Q8UWA5 7.46e-46 Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase II) (CA-II) Tribolodon hakonensis (Big-scaled redfin) (Leuciscus hakonensis) NA GO:0004089; GO:0005737; GO:0005886; GO:0008270 30831 XR_003824606.2 20 95 21 5 31 NA NA NA NA NA NA 30832 XM_029325161.2 570 352 348 683 380 Q29121 5.32e-164 Polypeptide N-acetylgalactosaminyltransferase 1 (EC 2.4.1.41) (Polypeptide GalNAc transferase 1) (GalNAc-T1) (pp-GaNTase 1) (Protein-UDP acetylgalactosaminyltransferase 1) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 1) [Cleaved into: Polypeptide N-acetylgalactosaminyltransferase 1 soluble form] Sus scrofa (Pig) protein O-linked glycosylation [GO:0006493] GO:0004653; GO:0005576; GO:0005794; GO:0006493; GO:0030145; GO:0030246; GO:0032580 30833 XM_029325161.2 570 352 348 683 380 Q29121 2.4e-128 Polypeptide N-acetylgalactosaminyltransferase 1 (EC 2.4.1.41) (Polypeptide GalNAc transferase 1) (GalNAc-T1) (pp-GaNTase 1) (Protein-UDP acetylgalactosaminyltransferase 1) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 1) [Cleaved into: Polypeptide N-acetylgalactosaminyltransferase 1 soluble form] Sus scrofa (Pig) protein O-linked glycosylation [GO:0006493] GO:0004653; GO:0005576; GO:0005794; GO:0006493; GO:0030145; GO:0030246; GO:0032580 30834 XM_029342780.2 278 347 190 249 196 NA NA NA NA NA NA 30835 XR_006397696.1 24 20 28 38 30 NA NA NA NA NA NA 30836 XM_044313614.1 85 68 57 67 52 Q16518 2.43e-101 Retinoid isomerohydrolase (EC 3.1.1.64) (All-trans-retinyl-palmitate hydrolase) (Lutein isomerase) (Meso-zeaxanthin isomerase) (EC 5.3.3.22) (Retinal pigment epithelium-specific 65 kDa protein) (Retinol isomerase) Homo sapiens (Human) cellular response to electrical stimulus [GO:0071257]; circadian rhythm [GO:0007623]; detection of light stimulus involved in visual perception [GO:0050908]; insulin receptor signaling pathway [GO:0008286]; neural retina development [GO:0003407]; regulation of gene expression [GO:0010468]; retina homeostasis [GO:0001895]; retina morphogenesis in camera-type eye [GO:0060042]; retinal metabolic process [GO:0042574]; retinoid metabolic process [GO:0001523]; visual perception [GO:0007601]; vitamin A metabolic process [GO:0006776]; zeaxanthin biosynthetic process [GO:1901827] GO:0001523; GO:0001786; GO:0001895; GO:0003407; GO:0005634; GO:0005789; GO:0005886; GO:0006776; GO:0007601; GO:0007623; GO:0008286; GO:0010468; GO:0016020; GO:0016702; GO:0016853; GO:0031210; GO:0042574; GO:0044297; GO:0046872; GO:0050251; GO:0050908; GO:0052884; GO:0052885; GO:0060042; GO:0071257; GO:1901612; GO:1901827 30837 XR_006395233.1 5096 4212 1060 1411 2479 Q9CYL5 4.75e-28 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Mus musculus (Mouse) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070374 30838 XM_029348764.2 22 16 33 29 0 Q570Y9 3.48e-59 DEP domain-containing mTOR-interacting protein (DEP domain-containing protein 6) Mus musculus (Mouse) intracellular signal transduction [GO:0035556]; negative regulation of cell size [GO:0045792]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of TOR signaling [GO:0032007]; negative regulation of TORC1 signaling [GO:1904262]; negative regulation of TORC2 signaling [GO:1903940]; regulation of extrinsic apoptotic signaling pathway [GO:2001236] GO:0006469; GO:0032007; GO:0035556; GO:0045792; GO:1903940; GO:1904262; GO:2001236 30839 XM_044315781.1 14 0 27 7 44 NA NA NA NA NA NA 30840 XM_029346114.2 2399 2068 916 2448 1730 Q3UJK4 0 GTP-binding protein 2 (GTP-binding-like protein 2) Mus musculus (Mouse) nuclear-transcribed mRNA catabolic process, no-go decay [GO:0070966]; rescue of stalled ribosome [GO:0072344]; translational elongation [GO:0006414] GO:0003746; GO:0003924; GO:0005525; GO:0006414; GO:0042802; GO:0070966; GO:0072344 30841 XM_029333691.2 5576 4901 2688 4152 4081 Q9BXS5 0 AP-1 complex subunit mu-1 (AP-mu chain family member mu1A) (Adaptor protein complex AP-1 subunit mu-1) (Adaptor-related protein complex 1 subunit mu-1) (Clathrin assembly protein complex 1 mu-1 medium chain 1) (Clathrin coat assembly protein AP47) (Clathrin coat-associated protein AP47) (Golgi adaptor HA1/AP1 adaptin mu-1 subunit) (Mu-adaptin 1) (Mu1A-adaptin) Homo sapiens (Human) endosome to melanosome transport [GO:0035646]; intracellular protein transport [GO:0006886]; melanosome assembly [GO:1903232]; melanosome organization [GO:0032438]; platelet dense granule organization [GO:0060155]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0005765; GO:0005769; GO:0005829; GO:0005886; GO:0006886; GO:0016020; GO:0016192; GO:0030121; GO:0030136; GO:0030659; GO:0031410; GO:0032438; GO:0032588; GO:0035579; GO:0035615; GO:0035646; GO:0060155; GO:0070062; GO:1903232 30842 XM_044321952.1 7 0 3 0 8 NA NA NA NA NA NA 30843 XM_029357621.2 16 21 17 76 138 NA NA NA NA NA NA 30844 XM_044320383.1 297 311 293 229 380 Q9NS61 3.29e-61 Kv channel-interacting protein 2 (KChIP2) (A-type potassium channel modulatory protein 2) (Cardiac voltage-gated potassium channel modulatory subunit) (Potassium channel-interacting protein 2) Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; clustering of voltage-gated potassium channels [GO:0045163]; detection of calcium ion [GO:0005513]; membrane repolarization [GO:0086009]; membrane repolarization during cardiac muscle cell action potential [GO:0086013]; muscle contraction [GO:0006936]; positive regulation of potassium ion export across plasma membrane [GO:1903766]; positive regulation of voltage-gated potassium channel activity [GO:1903818]; potassium ion export across plasma membrane [GO:0097623]; potassium ion transport [GO:0006813]; regulation of heart contraction [GO:0008016]; regulation of potassium ion transmembrane transport [GO:1901379]; signal transduction [GO:0007165] GO:0005244; GO:0005267; GO:0005509; GO:0005513; GO:0005737; GO:0005886; GO:0006813; GO:0006936; GO:0007165; GO:0007268; GO:0008016; GO:0008076; GO:0015459; GO:0030425; GO:0034705; GO:0042802; GO:0044325; GO:0044877; GO:0045163; GO:0045202; GO:0046923; GO:0047485; GO:0086009; GO:0086013; GO:0097623; GO:1901379; GO:1903766; GO:1903818 30845 XM_029336804.2 474 258 236 352 294 Q9UMZ2 1.72e-29 Synergin gamma (AP1 subunit gamma-binding protein 1) (Gamma-synergin) Homo sapiens (Human) endocytosis [GO:0006897]; intracellular protein transport [GO:0006886] GO:0005737; GO:0005794; GO:0006886; GO:0006897; GO:0030121; GO:0030130; GO:0048471 30846 XR_003823462.2 1 0 10 2 18 NA NA NA NA NA NA 30847 XR_006396301.1 181 159 193 421 429 NA NA NA NA NA NA 30848 XM_044327932.1 50 23 47 52 68 NA NA NA NA NA NA 30849 XM_029357757.2 655 469 418 702 797 Q91W82 4.36e-97 Ubiquitin-conjugating enzyme E2 E2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme E2) (Ubiquitin carrier protein E2) (Ubiquitin-protein ligase E2) Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; ISG15-protein conjugation [GO:0032020]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; protein K11-linked ubiquitination [GO:0070979]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209] GO:0000209; GO:0004842; GO:0005524; GO:0005634; GO:0006974; GO:0032020; GO:0042296; GO:0061631; GO:0070534; GO:0070936; GO:0070979; GO:1900087 30850 XM_044315405.1 0 59 4 33 33 NA NA NA NA NA NA 30851 XM_044312100.1 44 39 63 16 47 Q868M7 9.74e-156 Galactose/N-acetylgalactosamine-binding lectin CEL-III (Gal/GalNAc-binding lectin CEL-III) (CEL-III) (Hemolytic lectin CEL-III) (Lectin CEL-III) Cucumaria echinata (Sea cucumber) antibacterial humoral response [GO:0019731]; cell killing [GO:0001906]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; disruption of membrane integrity in another organism [GO:0051673]; hemolysis in another organism [GO:0044179]; positive regulation of erythrocyte aggregation [GO:0034120]; protein homooligomerization [GO:0051260] GO:0000287; GO:0001906; GO:0005509; GO:0005534; GO:0005615; GO:0019731; GO:0030395; GO:0034120; GO:0042806; GO:0043621; GO:0044179; GO:0046871; GO:0050829; GO:0050830; GO:0051260; GO:0051673; GO:1903777 30852 XM_044311850.1 50 23 0 17 32 NA NA NA NA NA NA 30853 XM_029337251.2 438 67 201 261 369 Q4V832 9.55e-35 AP-4 complex accessory subunit tepsin (Tetra-epsin) Xenopus laevis (African clawed frog) NA GO:0005794; GO:0005829; GO:0030662 30854 XM_044309696.1 0 3 0 17 29 NA NA NA NA NA NA 30855 XM_044314767.1 23 324 6 391 209 NA NA NA NA NA NA 30856 XM_029331686.2 552 270 115 279 414 NA NA NA NA NA NA 30857 XM_044319554.1 292 118 73 603 87 NA NA NA NA NA NA 30858 XM_044317755.1 136 92 92 174 99 NA NA NA NA NA NA 30859 XM_029328557.2 1353 1051 549 814 1022 NA NA NA NA NA NA 30860 XM_044324412.1 79 9 19 1042 818 NA NA NA NA NA NA 30861 XM_044329112.1 12 8 13 6 75 NA NA NA NA NA NA 30862 XM_029346598.2 575 312 181 351 227 NA NA NA NA NA NA 30863 XM_044311108.1 56 49 3 53 49 B8VIU6 3.05e-26 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 30864 XM_029324205.2 8 1 8 5 6 NA NA NA NA NA NA 30865 XR_006396163.1 25 10 61 12 106 NA NA NA NA NA NA 30866 XM_029353064.2 2651 3265 1690 1590 1405 Q28ID3 1.12e-147 Glutaredoxin-3 (Thioredoxin-like protein 2) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) [2Fe-2S] cluster assembly [GO:0044571]; protein maturation by iron-sulfur cluster transfer [GO:0097428] GO:0005829; GO:0044571; GO:0046872; GO:0051536; GO:0097428 30867 XM_044328520.1 162 228 323 382 332 Q9NVV5 6.86e-41 Androgen-induced gene 1 protein (AIG-1) (Fatty acid esters of hydroxy fatty acids hydrolase AIG1) (FAHFA hydrolase AIG1) (EC 3.1.-.-) Homo sapiens (Human) long-chain fatty acid catabolic process [GO:0042758] GO:0005886; GO:0012505; GO:0016020; GO:0016787; GO:0042758 30868 XM_029358682.2 759 855 432 644 673 Q6PBA2 1.97e-34 Protein LSM12 homolog A Danio rerio (Zebrafish) (Brachydanio rerio) NA NA 30869 XM_044328441.1 679 362 479 470 800 Q96QU8 0 Exportin-6 (Exp6) (Ran-binding protein 20) Homo sapiens (Human) protein export from nucleus [GO:0006611] GO:0005049; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0005886; GO:0006611; GO:0031267; GO:0032991 30870 XM_044316934.1 966 965 435 1194 1182 O94979 0 Protein transport protein Sec31A (ABP125) (ABP130) (SEC31-like protein 1) (SEC31-related protein A) (Web1-like protein) Homo sapiens (Human) COPII-coated vesicle cargo loading [GO:0090110]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; response to calcium ion [GO:0051592] GO:0005198; GO:0005737; GO:0005783; GO:0005789; GO:0005829; GO:0006886; GO:0006888; GO:0007029; GO:0012507; GO:0030120; GO:0030127; GO:0030134; GO:0043231; GO:0048306; GO:0048471; GO:0051592; GO:0070971; GO:0090110 30871 XM_044316934.1 966 965 435 1194 1182 O94979 1.13e-29 Protein transport protein Sec31A (ABP125) (ABP130) (SEC31-like protein 1) (SEC31-related protein A) (Web1-like protein) Homo sapiens (Human) COPII-coated vesicle cargo loading [GO:0090110]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; response to calcium ion [GO:0051592] GO:0005198; GO:0005737; GO:0005783; GO:0005789; GO:0005829; GO:0006886; GO:0006888; GO:0007029; GO:0012507; GO:0030120; GO:0030127; GO:0030134; GO:0043231; GO:0048306; GO:0048471; GO:0051592; GO:0070971; GO:0090110 30872 XM_029326905.2 1048 1144 649 810 868 NA NA NA NA NA NA 30873 XM_044321311.1 19 31 0 0 31 NA NA NA NA NA NA 30874 XM_029356512.2 145 102 0 139 148 Q3ZBX1 1.57e-91 Phosphatidylinositol N-acetylglucosaminyltransferase subunit C (Phosphatidylinositol-glycan biosynthesis class C protein) (PIG-C) Bos taurus (Bovine) GPI anchor biosynthetic process [GO:0006506] GO:0000506; GO:0006506 30875 XR_006393900.1 41 2 25 5 151 NA NA NA NA NA NA 30876 XM_029345469.2 37 0 0 91 7 Q8N2E2 1.42e-39 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 30877 XM_029345469.2 37 0 0 91 7 Q8N2E2 8.64e-38 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 30878 XM_029345469.2 37 0 0 91 7 Q8N2E2 1.54e-36 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 30879 XM_029345469.2 37 0 0 91 7 Q8N2E2 4.83e-35 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 30880 XM_029345469.2 37 0 0 91 7 Q8N2E2 5.71e-32 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 30881 XM_029345469.2 37 0 0 91 7 Q8N2E2 4.21e-25 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 30882 XM_044328195.1 1246 646 616 1232 986 Q6ZM86 4.25e-68 Delphilin (Glutamate receptor, ionotropic, delta 2-interacting protein 1) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0045211 30883 XR_006393491.1 9 11 16 5 74 NA NA NA NA NA NA 30884 XR_006392936.1 41 2 25 5 151 NA NA NA NA NA NA 30885 XM_044323427.1 222 178 84 237 590 Q1G7G9 2.3e-23 TALPID3 protein Gallus gallus (Chicken) centrosome localization [GO:0051642]; cilium assembly [GO:0060271]; motile cilium assembly [GO:0044458]; smoothened signaling pathway [GO:0007224] GO:0005737; GO:0005813; GO:0005814; GO:0007224; GO:0036064; GO:0044458; GO:0051642; GO:0060271 30886 XM_044313255.1 3 12 3 59 31 NA NA NA NA NA NA 30887 XM_029339007.2 13 0 12 15 49 P63018 0 Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) Rattus norvegicus (Rat) aging [GO:0007568]; ATP metabolic process [GO:0046034]; axo-dendritic transport [GO:0008088]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; cerebellum development [GO:0021549]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein folding [GO:0061077]; clathrin coat disassembly [GO:0072318]; estrous cycle [GO:0044849]; forebrain development [GO:0030900]; G1/S transition of mitotic cell cycle [GO:0000082]; kidney development [GO:0001822]; late endosomal microautophagy [GO:0061738]; maintenance of postsynaptic specialization structure [GO:0098880]; modulation by host of viral process [GO:0044788]; mRNA processing [GO:0006397]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of supramolecular fiber organization [GO:1902904]; positive regulation by host of viral genome replication [GO:0044829]; positive regulation of catalytic activity [GO:0043085]; positive regulation of gene expression [GO:0010628]; positive regulation of lysosomal membrane permeability [GO:0097214]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein refolding [GO:1904592]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein autophosphorylation [GO:0046777]; protein folding [GO:0006457]; protein import into nucleus [GO:0006606]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; protein transmembrane import into intracellular organelle [GO:0044743]; protein-containing complex disassembly [GO:0032984]; regulation of cell cycle [GO:0051726]; regulation of postsynapse organization [GO:0099175]; regulation of protein complex stability [GO:0061635]; regulation of protein stability [GO:0031647]; response to activity [GO:0014823]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to nickel cation [GO:0010045]; response to odorant [GO:1990834]; response to progesterone [GO:0032570]; response to starvation [GO:0042594]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; sensory perception of smell [GO:0007608]; skeletal muscle tissue development [GO:0007519]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192] GO:0000082; GO:0000974; GO:0001664; GO:0001786; GO:0001822; GO:0001916; GO:0001917; GO:0003723; GO:0005102; GO:0005524; GO:0005634; GO:0005681; GO:0005730; GO:0005737; GO:0005764; GO:0005765; GO:0005770; GO:0005776; GO:0005829; GO:0005874; GO:0005882; GO:0005886; GO:0006397; GO:0006457; GO:0006606; GO:0007519; GO:0007568; GO:0007608; GO:0008021; GO:0008088; GO:0008380; GO:0009408; GO:0009410; GO:0009986; GO:0010045; GO:0010628; GO:0010667; GO:0014069; GO:0014823; GO:0016191; GO:0016192; GO:0016887; GO:0019899; GO:0021549; GO:0030424; GO:0030425; GO:0030674; GO:0030900; GO:0031072; GO:0031625; GO:0031647; GO:0031686; GO:0032279; GO:0032355; GO:0032570; GO:0032984; GO:0032991; GO:0034605; GO:0034620; GO:0042026; GO:0042277; GO:0042470; GO:0042594; GO:0043005; GO:0043025; GO:0043085; GO:0043195; GO:0043197; GO:0043198; GO:0043202; GO:0043204; GO:0043531; GO:0044183; GO:0044309; GO:0044743; GO:0044788; GO:0044829; GO:0044849; GO:0045121; GO:0045471; GO:0045862; GO:0045892; GO:0046034; GO:0046777; GO:0048026; GO:0048471; GO:0050766; GO:0051082; GO:0051085; GO:0051087; GO:0051726; GO:0051787; GO:0055131; GO:0061077; GO:0061635; GO:0061684; GO:0061738; GO:0061740; GO:0070062; GO:0071276; GO:0072318; GO:0097214; GO:0098684; GO:0098690; GO:0098793; GO:0098794; GO:0098880; GO:0098978; GO:0099175; GO:0099523; GO:0099524; GO:0099634; GO:0101031; GO:0140545; GO:0140662; GO:1902904; GO:1903206; GO:1904592; GO:1904593; GO:1904764; GO:1990124; GO:1990832; GO:1990833; GO:1990834; GO:1990836; GO:1990904 30888 XM_029351439.2 2106 1670 1389 2040 1737 Q6PB93 0 Polypeptide N-acetylgalactosaminyltransferase 2 (EC 2.4.1.41) (Polypeptide GalNAc transferase 2) (GalNAc-T2) (pp-GaNTase 2) (Protein-UDP acetylgalactosaminyltransferase 2) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 2) [Cleaved into: Polypeptide N-acetylgalactosaminyltransferase 2 soluble form] Mus musculus (Mouse) O-glycan processing [GO:0016266]; protein maturation [GO:0051604]; protein O-linked glycosylation [GO:0006493]; protein O-linked glycosylation via serine [GO:0018242]; protein O-linked glycosylation via threonine [GO:0018243] GO:0004653; GO:0005576; GO:0005794; GO:0005795; GO:0005796; GO:0006493; GO:0016266; GO:0018242; GO:0018243; GO:0030145; GO:0030246; GO:0032580; GO:0048471; GO:0051604 30889 XM_044321743.1 1367 1099 760 1675 1133 NA NA NA NA NA NA 30890 XM_029334643.1 7745 10079 5956 6789 5553 P61359 8.64e-59 60S ribosomal protein L27 Hippocampus comes (Tiger tail seahorse) erythrocyte differentiation [GO:0030218]; translation [GO:0006412] GO:0003735; GO:0005829; GO:0006412; GO:0015934; GO:0030218; GO:0098556 30891 XM_029329631.2 539 328 214 290 411 O42260 3.43e-52 Gem-associated protein 2 (Gemin-2) (Component of gems 2) (Survival of motor neuron protein-interacting protein 1) (SMN-interacting protein 1) Xenopus laevis (African clawed frog) spliceosomal complex assembly [GO:0000245]; spliceosomal snRNP assembly [GO:0000387] GO:0000245; GO:0000387; GO:0005681; GO:0005829; GO:0032797; GO:0034719; GO:0097504 30892 XM_029353721.2 165 44 100 168 159 P00727 9.02e-163 Cytosol aminopeptidase (EC 3.4.11.1) (Cysteinylglycine-S-conjugate dipeptidase) (EC 3.4.13.23) (Leucine aminopeptidase 3) (LAP-3) (Leucyl aminopeptidase) (LAP) (Peptidase S) (Proline aminopeptidase) (EC 3.4.11.5) (Prolyl aminopeptidase) Bos taurus (Bovine) proteolysis [GO:0006508] GO:0004180; GO:0005654; GO:0005737; GO:0005739; GO:0005829; GO:0006508; GO:0008233; GO:0016805; GO:0030145; GO:0030496; GO:0070006; GO:0097718 30893 XM_029342397.2 152 141 114 158 58 Q95JD5 9.88e-56 Sulfotransferase 1B1 (ST1B1) (cSULT1B1) (EC 2.8.2.1) (Sulfotransferase family cytosolic 1B member 1) Canis lupus familiaris (Dog) (Canis familiaris) 3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; epithelial cell differentiation [GO:0030855]; ethanol catabolic process [GO:0006068]; flavonoid metabolic process [GO:0009812]; sulfation [GO:0051923]; thyroid hormone metabolic process [GO:0042403]; xenobiotic metabolic process [GO:0006805] GO:0004062; GO:0005737; GO:0006068; GO:0006805; GO:0008146; GO:0009812; GO:0030855; GO:0042403; GO:0050427; GO:0051923 30894 XM_044318950.1 3 0 4 8 45 Q9DDA9 2.25e-80 Protein kinase C and casein kinase substrate in neurons protein 2 (x-PACSIN2) Xenopus laevis (African clawed frog) actin cytoskeleton organization [GO:0030036]; caveola assembly [GO:0070836]; endocytosis [GO:0006897]; plasma membrane tubulation [GO:0097320] GO:0005769; GO:0005856; GO:0005901; GO:0006897; GO:0030036; GO:0032587; GO:0055038; GO:0070300; GO:0070836; GO:0097320 30895 XM_044315822.1 134 284 48 133 129 NA NA NA NA NA NA 30896 XM_029332425.2 399 231 310 331 333 NA NA NA NA NA NA 30897 XM_029341039.2 0 3 0 0 7 NA NA NA NA NA NA 30898 XM_044314062.1 49 8 8 0 26 NA NA NA NA NA NA 30899 XM_044324263.1 1436 670 593 832 558 P07949 3.01e-77 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; axon guidance [GO:0007411]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; lymphocyte migration into lymphoid organs [GO:0097021]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; posterior midgut development [GO:0007497]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006468; GO:0006919; GO:0007156; GO:0007158; GO:0007165; GO:0007169; GO:0007411; GO:0007497; GO:0009410; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0038023; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0097021; GO:0098797; GO:2001241 30900 XM_044311517.1 0 0 10 29 7 NA NA NA NA NA NA 30901 XM_044317186.1 14 8 0 6 5 NA NA NA NA NA NA 30902 XM_029357629.2 2424 1418 994 3100 2161 A5PKG7 3.83e-88 BTB/POZ domain-containing protein KCTD5 Bos taurus (Bovine) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein homooligomerization [GO:0051260] GO:0005634; GO:0005737; GO:0005829; GO:0031463; GO:0043161; GO:0051260; GO:0097602 30903 XM_029337656.2 12 7 0 9 0 NA NA NA NA NA NA 30904 XM_029334480.2 49 0 16 32 16 Q3U9N9 5.28e-52 Monocarboxylate transporter 10 (MCT 10) (Aromatic amino acid transporter 1) (Solute carrier family 16 member 10) (T-type amino acid transporter 1) Mus musculus (Mouse) aromatic amino acid transport [GO:0015801]; thyroid hormone generation [GO:0006590]; thyroid hormone transport [GO:0070327]; thyroid-stimulating hormone secretion [GO:0070460] GO:0005302; GO:0005886; GO:0006590; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0030054; GO:0043231; GO:0070327; GO:0070460 30905 XR_006393913.1 41 2 25 5 151 NA NA NA NA NA NA 30906 XM_044324735.1 45 391 62 366 540 NA NA NA NA NA NA 30907 XM_029325295.2 7 12 16 11 0 NA NA NA NA NA NA 30908 XM_029338163.2 1027 924 359 550 826 Q4FZX7 5.44e-65 Signal recognition particle receptor subunit beta (SR-beta) Rattus norvegicus (Rat) protein targeting to ER [GO:0045047] GO:0005525; GO:0005737; GO:0005785; GO:0005881; GO:0016020; GO:0031625; GO:0045047 30909 XM_044325341.1 20 0 3 17 15 NA NA NA NA NA NA 30910 XM_044311356.1 80 34 108 38 383 NA NA NA NA NA NA 30911 XM_044309609.1 0 30 30 6 0 NA NA NA NA NA NA 30912 XR_006393594.1 0 0 0 10 0 NA NA NA NA NA NA 30913 XM_029350761.2 13 101 93 26 226 P51029 2.6e-71 Protein Wnt-8b Danio rerio (Zebrafish) (Brachydanio rerio) canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; commissural neuron axon guidance [GO:0071679]; embryonic pattern specification [GO:0009880]; eye development [GO:0001654]; eye field cell fate commitment involved in camera-type eye formation [GO:0060898]; forebrain development [GO:0030900]; forebrain neuron differentiation [GO:0021879]; hypothalamus development [GO:0021854]; negative regulation of anterior neural cell fate commitment of the neural plate by Wnt signaling pathway [GO:0022002]; neuron differentiation [GO:0030182]; otic placode formation [GO:0043049]; sensory epithelium regeneration [GO:0070654] GO:0001654; GO:0005109; GO:0005125; GO:0005615; GO:0009880; GO:0021854; GO:0021879; GO:0022002; GO:0030182; GO:0030900; GO:0043049; GO:0045165; GO:0060070; GO:0060898; GO:0070654; GO:0071679 30914 XM_029347571.2 38 27 26 52 78 NA NA NA NA NA NA 30915 XM_044316343.1 17 18 9 42 29 Q96AY4 2.05e-61 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30916 XM_044316343.1 17 18 9 42 29 Q96AY4 2.27e-56 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30917 XM_044316343.1 17 18 9 42 29 Q96AY4 3.74e-54 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30918 XM_044316343.1 17 18 9 42 29 Q96AY4 3.47e-49 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30919 XM_044316343.1 17 18 9 42 29 Q96AY4 4.24e-49 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30920 XM_044316343.1 17 18 9 42 29 Q96AY4 6.11e-48 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30921 XM_044316343.1 17 18 9 42 29 Q96AY4 2.78e-47 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30922 XM_044316343.1 17 18 9 42 29 Q96AY4 8.46e-47 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30923 XM_044316343.1 17 18 9 42 29 Q96AY4 1.35e-45 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30924 XM_044316343.1 17 18 9 42 29 Q96AY4 3.33e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30925 XM_044316343.1 17 18 9 42 29 Q96AY4 8.22e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30926 XM_044316343.1 17 18 9 42 29 Q96AY4 1.47e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30927 XM_044316343.1 17 18 9 42 29 Q96AY4 8.49e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30928 XM_044312371.1 4 1 5 0 10 NA NA NA NA NA NA 30929 XM_044309297.1 5 4 5 0 15 NA NA NA NA NA NA 30930 XM_029336924.2 2988 2562 1832 3912 3574 P11387 0 DNA topoisomerase 1 (EC 5.6.2.1) (DNA topoisomerase I) Homo sapiens (Human) chromatin remodeling [GO:0006338]; chromosome segregation [GO:0007059]; circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; DNA replication [GO:0006260]; DNA topological change [GO:0006265]; embryonic cleavage [GO:0040016]; peptidyl-serine phosphorylation [GO:0018105]; phosphorylation [GO:0016310]; programmed cell death [GO:0012501]; response to xenobiotic stimulus [GO:0009410] GO:0000932; GO:0000978; GO:0001650; GO:0001673; GO:0003677; GO:0003682; GO:0003690; GO:0003697; GO:0003723; GO:0003917; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005694; GO:0005730; GO:0006260; GO:0006265; GO:0006338; GO:0007059; GO:0007623; GO:0008301; GO:0009410; GO:0012501; GO:0016310; GO:0018105; GO:0019904; GO:0032922; GO:0032993; GO:0040016; GO:0043204; GO:0097100 30931 XM_044308764.1 4692 5944 3376 4210 2415 Q0KIA2 6.31e-54 PP2C-like domain-containing protein CG9801 Drosophila melanogaster (Fruit fly) NA NA 30932 XM_029347867.2 0 0 26 9 0 NA NA NA NA NA NA 30933 XM_029343330.2 0 0 9 0 0 NA NA NA NA NA NA 30934 XM_029326099.2 26 19 10 34 15 NA NA NA NA NA NA 30935 XM_044327106.1 0 2 16 58 3 NA NA NA NA NA NA 30936 XM_029348739.2 98 75 31 73 59 Q8IWL3 1.37e-30 Iron-sulfur cluster co-chaperone protein HscB (DnaJ homolog subfamily C member 20) [Cleaved into: Iron-sulfur cluster co-chaperone protein HscB, cytoplasmic (C-HSC20); Iron-sulfur cluster co-chaperone protein HscB, mitochondrial] Homo sapiens (Human) [2Fe-2S] cluster assembly [GO:0044571]; iron-sulfur cluster assembly [GO:0016226]; primitive erythrocyte differentiation [GO:0060319]; primitive hemopoiesis [GO:0060215]; protein complex oligomerization [GO:0051259] GO:0001671; GO:0005654; GO:0005737; GO:0005739; GO:0005829; GO:0016226; GO:0042802; GO:0044571; GO:0046872; GO:0051087; GO:0051259; GO:0060215; GO:0060319 30937 XM_044308506.1 217 78 112 121 115 E7FAM5 2.74e-60 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 30938 XM_044308506.1 217 78 112 121 115 E7FAM5 2.4e-53 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 30939 XM_029335705.2 10380 7110 5302 9453 6669 B3DLH6 0 Myoferlin (Fer-1-like protein 3) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) plasma membrane repair [GO:0001778] GO:0001778; GO:0005543; GO:0005901; GO:0030659; GO:0031965; GO:0046872 30940 XR_006393737.1 26 16 39 31 193 NA NA NA NA NA NA 30941 XM_044307945.1 22 32 57 27 48 NA NA NA NA NA NA 30942 XM_044322881.1 10 2 2 7 0 NA NA NA NA NA NA 30943 XM_044311082.1 17 4 0 0 7 Q9TXJ8 6.37e-27 Putative ATP-dependent DNA helicase Q1 (EC 3.6.4.12) Caenorhabditis elegans DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724] GO:0000724; GO:0003676; GO:0005524; GO:0005634; GO:0005694; GO:0005737; GO:0006268; GO:0006281; GO:0006310; GO:0009378; GO:0016887; GO:0032508; GO:0043138 30944 XM_029354869.2 18 49 3 64 48 A0A1U9YHZ9 1.64e-37 Cytochrome P450 monooxygenase verC (EC 1.-.-.-) (Verticillin biosynthesis cluster protein C) Clonostachys rogersoniana NA GO:0004497; GO:0005506; GO:0016020; GO:0016705; GO:0020037 30945 XM_029345674.2 0 325 31 0 0 Q8K0Q5 1.59e-95 Rho GTPase-activating protein 18 (Rho-type GTPase-activating protein 18) Mus musculus (Mouse) regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin filament polymerization [GO:0030833]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of small GTPase mediated signal transduction [GO:0051056]; small GTPase mediated signal transduction [GO:0007264] GO:0001726; GO:0005096; GO:0005737; GO:0005829; GO:0005881; GO:0005886; GO:0007264; GO:0008360; GO:0016607; GO:0030833; GO:0032956; GO:0051056; GO:2000145 30946 XM_029336087.2 12 15 17 17 23 D3ZVM4 4.48e-75 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Rattus norvegicus (Rat) 3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to organic substance [GO:0071310]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA processing [GO:0035196]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; post-transcriptional regulation of gene expression [GO:0010608]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein metabolic process [GO:0051246]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0001843; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0010608; GO:0016567; GO:0017148; GO:0021915; GO:0030371; GO:0035196; GO:0035198; GO:0035278; GO:0043161; GO:0051246; GO:0051865; GO:0060964; GO:0061158; GO:0061630; GO:0071310; GO:0072089; GO:2000177; GO:2000637 30947 XM_029350867.2 5 1 19 0 78 NA NA NA NA NA NA 30948 XM_029351945.2 5 9 6 8 3 NA NA NA NA NA NA 30949 XR_006396180.1 64 15 27 13 231 NA NA NA NA NA NA 30950 XR_006394682.1 0 0 0 36 0 NA NA NA NA NA NA 30951 XM_029354068.2 369 233 178 261 357 P43352 3.33e-72 DNA repair protein RAD52 homolog Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; cellular response to oxidative stress [GO:0034599]; DNA double-strand break processing involved in repair via single-strand annealing [GO:0010792]; DNA recombinase assembly [GO:0000730]; DNA recombination [GO:0006310]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via single-strand annealing [GO:0045002]; mitotic recombination [GO:0006312]; regulation of nucleotide-excision repair [GO:2000819] GO:0000724; GO:0000730; GO:0003677; GO:0003697; GO:0005634; GO:0006310; GO:0006312; GO:0006974; GO:0010792; GO:0032991; GO:0032993; GO:0034599; GO:0042802; GO:0045002; GO:2000819 30952 XR_006397495.1 34 41 37 31 88 NA NA NA NA NA NA 30953 XM_029341625.2 1356 787 850 1121 1119 Q6P158 0 Putative ATP-dependent RNA helicase DHX57 (EC 3.6.4.13) (DEAH box protein 57) Homo sapiens (Human) NA GO:0003723; GO:0003724; GO:0005524; GO:0016887; GO:0046872 30954 XM_029328662.2 26 10 6 6 1 P56434 5.14e-46 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6 (EC 2.4.1.152) (Fucosyltransferase 6) (Fucosyltransferase VI) (Fuc-TVI) (FucT-VI) (Galactoside 3-L-fucosyltransferase) Pan troglodytes (Chimpanzee) fucosylation [GO:0036065]; glycosphingolipid biosynthetic process [GO:0006688]; N-glycan fucosylation [GO:0036071]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493] GO:0005576; GO:0005794; GO:0006487; GO:0006493; GO:0006688; GO:0017083; GO:0032580; GO:0036065; GO:0036071; GO:0046920 30955 XM_029353239.2 277 251 130 325 249 Q7L273 6.16e-145 BTB/POZ domain-containing protein KCTD9 Homo sapiens (Human) intracellular signal transduction [GO:0035556]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567] GO:0016567; GO:0035556; GO:0042802; GO:0043621; GO:0051260; GO:0097602 30956 XM_029333512.2 1169 646 158 500 637 Q61382 8.35e-34 TNF receptor-associated factor 4 (EC 2.3.2.27) (Cysteine-rich motif associated to RING and Traf domains protein 1) Mus musculus (Mouse) activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; innate immune response [GO:0045087]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein kinase activity [GO:0045860]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; respiratory gaseous exchange by respiratory system [GO:0007585]; respiratory tube development [GO:0030323] GO:0001650; GO:0005164; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0005923; GO:0006915; GO:0007250; GO:0007585; GO:0008270; GO:0016740; GO:0019901; GO:0030323; GO:0031625; GO:0031996; GO:0042802; GO:0042981; GO:0043122; GO:0043161; GO:0045087; GO:0045860; GO:0046330; GO:0048471; GO:0050699 30957 XM_029358000.2 1526 1243 808 1054 730 Q91618 5.06e-103 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase) Xenopus laevis (African clawed frog) cell cycle [GO:0007049]; protein phosphorylation [GO:0006468] GO:0000139; GO:0004674; GO:0005524; GO:0005789; GO:0006468; GO:0007049; GO:0046872; GO:0106310 30958 XM_044323319.1 124 124 0 161 5 NA NA NA NA NA NA 30959 XR_006391975.1 0 8 0 0 0 NA NA NA NA NA NA 30960 XM_044328168.1 446 241 247 433 375 Q80Y81 5.54e-81 Zinc phosphodiesterase ELAC protein 2 (EC 3.1.26.11) (ElaC homolog protein 2) (Ribonuclease Z 2) (RNase Z 2) (tRNA 3 endonuclease 2) (tRNase Z 2) Mus musculus (Mouse) mitochondrial tRNA 3'-trailer cleavage, endonucleolytic [GO:0072684] GO:0004549; GO:0005634; GO:0005654; GO:0005739; GO:0042645; GO:0042781; GO:0046872; GO:0072684 30961 XM_044311883.1 32 27 0 0 0 NA NA NA NA NA NA 30962 XM_029344770.2 8 5 9 3 5 NA NA NA NA NA NA 30963 XM_029337378.2 348 493 146 532 177 NA NA NA NA NA NA 30964 XR_006397019.1 21 59 48 103 205 NA NA NA NA NA NA 30965 XM_029334332.2 60 358 0 0 615 E9PUQ8 0 Diacylglycerol kinase delta (DAG kinase delta) (EC 2.7.1.107) Mus musculus (Mouse) diacylglycerol metabolic process [GO:0046339]; endocytosis [GO:0006897]; intracellular signal transduction [GO:0035556]; lipid phosphorylation [GO:0046834]; negative regulation of protein kinase C signaling [GO:0090038]; phosphatidic acid biosynthetic process [GO:0006654]; positive regulation of clathrin-dependent endocytosis [GO:2000370]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; protein transport [GO:0015031]; response to organic substance [GO:0010033] GO:0004143; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0005905; GO:0006654; GO:0006897; GO:0007205; GO:0010033; GO:0015031; GO:0019900; GO:0031410; GO:0035556; GO:0042802; GO:0042803; GO:0045742; GO:0046339; GO:0046834; GO:0046872; GO:0046982; GO:0090038; GO:2000370 30966 XM_044322682.1 0 0 0 9 0 NA NA NA NA NA NA 30967 XM_044307703.1 434 210 189 372 442 NA NA NA NA NA NA 30968 XR_006396738.1 16 0 5 20 103 NA NA NA NA NA NA 30969 XM_029348923.2 618 563 363 618 710 Q6P360 6.09e-121 E3 ubiquitin ligase Rnf121 (EC 2.3.2.27) (RING finger protein 121) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0016020; GO:0046872 30970 XR_006394338.1 10 11 7 18 8 NA NA NA NA NA NA 30971 XM_029335462.2 822 607 211 619 905 NA NA NA NA NA NA 30972 XM_044307788.1 43 10 12 23 23 NA NA NA NA NA NA 30973 XM_044327701.1 22 42 114 94 110 NA NA NA NA NA NA 30974 XM_029338191.2 1225 1033 483 775 462 NA NA NA NA NA NA 30975 XM_044327025.1 0 1 13 18 13 NA NA NA NA NA NA 30976 XR_006392835.1 476 273 116 461 112 NA NA NA NA NA NA 30977 XM_044318298.1 16 16 11 80 20 Q96CG8 1.23e-35 Collagen triple helix repeat-containing protein 1 Homo sapiens (Human) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005576; GO:0005581; GO:0005615; GO:0016477; GO:0016528; GO:0017147; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0062023; GO:0090090; GO:0090103; GO:0090177 30978 XR_003827664.2 5 0 0 7 6 NA NA NA NA NA NA 30979 XM_029330407.2 202 0 26 290 350 NA NA NA NA NA NA 30980 XM_044326979.1 132 64 0 43 0 Q28107 1.92e-25 Coagulation factor V (Activated protein C cofactor) [Cleaved into: Coagulation factor V heavy chain; Coagulation factor V light chain] Bos taurus (Bovine) blood circulation [GO:0008015]; blood coagulation [GO:0007596] GO:0005507; GO:0005576; GO:0007596; GO:0008015; GO:0031091 30981 XR_006391770.1 1290 588 721 1218 923 Q9VCA2 1.03e-56 Organic cation transporter protein Drosophila melanogaster (Fruit fly) apoptotic process [GO:0006915]; ion transport [GO:0006811] GO:0006811; GO:0006915; GO:0016020; GO:0022857 30982 XR_006391770.1 1290 588 721 1218 923 Q9VCA2 1.03e-56 Organic cation transporter protein Drosophila melanogaster (Fruit fly) apoptotic process [GO:0006915]; ion transport [GO:0006811] GO:0006811; GO:0006915; GO:0016020; GO:0022857 30983 XR_006391269.1 113 410 172 233 161 NA NA NA NA NA NA 30984 XM_029330116.2 819 488 818 662 870 Q5ZM55 1.05e-70 Protein fem-1 homolog B (FEM1b) (FEM1-beta) Gallus gallus (Chicken) apoptotic process [GO:0006915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of DNA damage checkpoint [GO:2000001]; ubiquitin-dependent protein catabolic process via the C-end degron rule pathway [GO:0140627] GO:0005634; GO:0005737; GO:0006915; GO:0016567; GO:0031462; GO:0043161; GO:0140627; GO:1990756; GO:2000001 30985 XR_006394207.1 9 8 5 12 17 NA NA NA NA NA NA 30986 XR_006393957.1 23 23 0 7 50 NA NA NA NA NA NA 30987 XM_044326716.1 483 429 366 463 562 Q8IZF6 5.15e-51 Adhesion G-protein coupled receptor G4 (G-protein coupled receptor 112) Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0005886; GO:0007166; GO:0007186; GO:0007189; GO:0016020 30988 XR_006395307.1 33 7 10 26 12 NA NA NA NA NA NA 30989 XR_006392627.1 2 6 29 6 55 NA NA NA NA NA NA 30990 XM_044314106.1 387 401 239 409 304 Q5ZLK1 3.02e-149 DDB1- and CUL4-associated factor 13 (WD repeat and SOF domain-containing protein 1) Gallus gallus (Chicken) maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; protein ubiquitination [GO:0016567] GO:0000462; GO:0005730; GO:0016567; GO:0032040; GO:0080008 30991 XM_029336835.2 704 1151 642 628 418 NA NA NA NA NA NA 30992 XM_044318935.1 18 27 0 3 40 O64411 5.29e-56 Polyamine oxidase 1 (EC 1.5.3.14) (EC 1.5.3.15) Zea mays (Maize) polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208] GO:0006598; GO:0009505; GO:0016491; GO:0046208; GO:0046592; GO:0048046; GO:0050660; GO:0052893; GO:0052896; GO:0052897; GO:0052900 30993 XM_044325646.1 486 171 204 159 233 P70085 1.6e-94 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Oryzias latipes (Japanese rice fish) (Japanese killifish) hormone biosynthetic process [GO:0042446]; progesterone metabolic process [GO:0042448]; steroid biosynthetic process [GO:0006694] GO:0004508; GO:0005506; GO:0006694; GO:0016020; GO:0020037; GO:0042446; GO:0042448; GO:0047442 30994 XM_044322540.1 0 11 1 23 7 O70624 6.77e-45 Myocilin (Trabecular meshwork-induced glucocorticoid response protein) [Cleaved into: Myocilin, N-terminal fragment (Myocilin 20 kDa N-terminal fragment); Myocilin, C-terminal fragment (Myocilin 35 kDa N-terminal fragment)] Mus musculus (Mouse) bone development [GO:0060348]; clustering of voltage-gated sodium channels [GO:0045162]; ERBB2-ERBB3 signaling pathway [GO:0038133]; myelination in peripheral nervous system [GO:0022011]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of stress fiber assembly [GO:0051497]; neuron projection development [GO:0031175]; non-canonical Wnt signaling pathway via JNK cascade [GO:0038031]; osteoblast differentiation [GO:0001649]; positive regulation of cell migration [GO:0030335]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of MAPK cascade [GO:0043408]; signal transduction [GO:0007165]; skeletal muscle hypertrophy [GO:0014734] GO:0001649; GO:0001953; GO:0001968; GO:0005109; GO:0005615; GO:0005737; GO:0005741; GO:0005743; GO:0005758; GO:0005783; GO:0005791; GO:0005794; GO:0005929; GO:0007165; GO:0014068; GO:0014734; GO:0022011; GO:0030335; GO:0030971; GO:0031175; GO:0031410; GO:0032027; GO:0033268; GO:0035024; GO:0035748; GO:0038031; GO:0038133; GO:0043220; GO:0043408; GO:0045162; GO:0046872; GO:0051496; GO:0051497; GO:0051894; GO:0051897; GO:0051901; GO:0060348; GO:0062023; GO:0070062; GO:0097453; GO:1900026 30995 XM_044317679.1 167 25 0 0 0 NA NA NA NA NA NA 30996 XM_044321657.1 1 30 2 21 17 Q86WI3 3.33e-30 Protein NLRC5 (Caterpiller protein 16.1) (CLR16.1) (Nucleotide-binding oligomerization domain protein 27) (Nucleotide-binding oligomerization domain protein 4) Homo sapiens (Human) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of type II interferon-mediated signaling pathway [GO:0060335]; regulation of kinase activity [GO:0043549]; response to bacterium [GO:0009617] GO:0000978; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0009617; GO:0032088; GO:0035556; GO:0043549; GO:0045087; GO:0045345; GO:0045944; GO:0051607; GO:0060335; GO:0060339; GO:0060340 30997 XM_044314726.1 24 53 14 49 81 NA NA NA NA NA NA 30998 XM_044318226.1 1072 734 281 665 733 Q7ZWF0 0 mRNA export factor (Rae1 protein homolog) (mRNA-associated protein mrnp 41) Danio rerio (Zebrafish) (Brachydanio rerio) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic spindle organization [GO:0060236]; RNA export from nucleus [GO:0006405]; transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000972] GO:0000972; GO:0003723; GO:0005643; GO:0005737; GO:0006405; GO:0007049; GO:0043130; GO:0051301; GO:0060236; GO:0097431 30999 XM_044318077.1 45 0 0 51 4 Q9M2U3 6.75e-35 Protein ALP1-like (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) NA GO:0000118; GO:0004518; GO:0046872 31000 XR_006394757.1 125 144 120 161 162 NA NA NA NA NA NA 31001 XR_003823126.2 18 0 1 0 1 NA NA NA NA NA NA 31002 XM_044325556.1 0 27 0 23 16 NA NA NA NA NA NA 31003 XM_044310765.1 35 47 42 76 47 NA NA NA NA NA NA 31004 XR_003827195.2 7 0 7 34 26 NA NA NA NA NA NA 31005 XM_044316616.1 7 72 44 36 0 NA NA NA NA NA NA 31006 XM_029344207.2 36 0 13 67 11 NA NA NA NA NA NA 31007 XM_029358135.2 1047 1020 545 1236 921 NA NA NA NA NA NA 31008 XR_003827916.1 29 34 56 30 35 NA NA NA NA NA NA 31009 XM_044315712.1 476 95 216 244 195 NA NA NA NA NA NA 31010 XM_029342559.2 683 797 436 1030 823 Q9D0B6 3.42e-50 Protein PBDC1 (Polysaccharide biosynthesis domain-containing protein 1) Mus musculus (Mouse) NA NA 31011 XM_029346605.2 944 993 947 1334 672 NA NA NA NA NA NA 31012 XM_029355394.2 33 3 25 55 47 NA NA NA NA NA NA 31013 XM_029330772.2 37 34 11 46 32 Q9ZWT2 3.07e-23 Cytochrome B5 isoform D (AtCb5-D) (Cytochrome b5 isoform B) (AtCb5-B) Arabidopsis thaliana (Mouse-ear cress) NA GO:0005783; GO:0005789; GO:0009536; GO:0016020; GO:0020037; GO:0043231; GO:0046872 31014 XM_044311279.1 5 24 13 0 17 NA NA NA NA NA NA 31015 XM_029358399.2 2787 2536 1575 3790 2483 Q55G75 1.56e-58 PH domain-containing protein DDB_G0267786 Dictyostelium discoideum (Social amoeba) NA NA 31016 XM_029353552.2 0 16 0 0 0 Q02357 3.88e-67 Ankyrin-1 (ANK-1) (Erythrocyte ankyrin) Mus musculus (Mouse) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; erythrocyte development [GO:0048821]; inorganic cation transmembrane transport [GO:0098662]; iron ion homeostasis [GO:0055072]; porphyrin-containing compound biosynthetic process [GO:0006779]; positive regulation of organelle organization [GO:0010638]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005634; GO:0005886; GO:0006779; GO:0006888; GO:0007165; GO:0008093; GO:0009898; GO:0010638; GO:0014731; GO:0016020; GO:0016529; GO:0019899; GO:0019903; GO:0030018; GO:0030507; GO:0030673; GO:0030863; GO:0031430; GO:0031672; GO:0042383; GO:0043005; GO:0044325; GO:0045211; GO:0048821; GO:0051117; GO:0055072; GO:0072659; GO:0098662 31017 XM_029353552.2 0 16 0 0 0 Q02357 4.29e-59 Ankyrin-1 (ANK-1) (Erythrocyte ankyrin) Mus musculus (Mouse) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; erythrocyte development [GO:0048821]; inorganic cation transmembrane transport [GO:0098662]; iron ion homeostasis [GO:0055072]; porphyrin-containing compound biosynthetic process [GO:0006779]; positive regulation of organelle organization [GO:0010638]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005634; GO:0005886; GO:0006779; GO:0006888; GO:0007165; GO:0008093; GO:0009898; GO:0010638; GO:0014731; GO:0016020; GO:0016529; GO:0019899; GO:0019903; GO:0030018; GO:0030507; GO:0030673; GO:0030863; GO:0031430; GO:0031672; GO:0042383; GO:0043005; GO:0044325; GO:0045211; GO:0048821; GO:0051117; GO:0055072; GO:0072659; GO:0098662 31018 XM_029353552.2 0 16 0 0 0 Q02357 2.6e-46 Ankyrin-1 (ANK-1) (Erythrocyte ankyrin) Mus musculus (Mouse) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; erythrocyte development [GO:0048821]; inorganic cation transmembrane transport [GO:0098662]; iron ion homeostasis [GO:0055072]; porphyrin-containing compound biosynthetic process [GO:0006779]; positive regulation of organelle organization [GO:0010638]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005634; GO:0005886; GO:0006779; GO:0006888; GO:0007165; GO:0008093; GO:0009898; GO:0010638; GO:0014731; GO:0016020; GO:0016529; GO:0019899; GO:0019903; GO:0030018; GO:0030507; GO:0030673; GO:0030863; GO:0031430; GO:0031672; GO:0042383; GO:0043005; GO:0044325; GO:0045211; GO:0048821; GO:0051117; GO:0055072; GO:0072659; GO:0098662 31019 XM_029353552.2 0 16 0 0 0 Q02357 1.3e-44 Ankyrin-1 (ANK-1) (Erythrocyte ankyrin) Mus musculus (Mouse) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; erythrocyte development [GO:0048821]; inorganic cation transmembrane transport [GO:0098662]; iron ion homeostasis [GO:0055072]; porphyrin-containing compound biosynthetic process [GO:0006779]; positive regulation of organelle organization [GO:0010638]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005634; GO:0005886; GO:0006779; GO:0006888; GO:0007165; GO:0008093; GO:0009898; GO:0010638; GO:0014731; GO:0016020; GO:0016529; GO:0019899; GO:0019903; GO:0030018; GO:0030507; GO:0030673; GO:0030863; GO:0031430; GO:0031672; GO:0042383; GO:0043005; GO:0044325; GO:0045211; GO:0048821; GO:0051117; GO:0055072; GO:0072659; GO:0098662 31020 XM_029353552.2 0 16 0 0 0 Q02357 6.43e-23 Ankyrin-1 (ANK-1) (Erythrocyte ankyrin) Mus musculus (Mouse) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; erythrocyte development [GO:0048821]; inorganic cation transmembrane transport [GO:0098662]; iron ion homeostasis [GO:0055072]; porphyrin-containing compound biosynthetic process [GO:0006779]; positive regulation of organelle organization [GO:0010638]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005634; GO:0005886; GO:0006779; GO:0006888; GO:0007165; GO:0008093; GO:0009898; GO:0010638; GO:0014731; GO:0016020; GO:0016529; GO:0019899; GO:0019903; GO:0030018; GO:0030507; GO:0030673; GO:0030863; GO:0031430; GO:0031672; GO:0042383; GO:0043005; GO:0044325; GO:0045211; GO:0048821; GO:0051117; GO:0055072; GO:0072659; GO:0098662 31021 XM_044310200.1 184 6 0 82 152 NA NA NA NA NA NA 31022 XM_044310297.1 210 79 91 205 423 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31023 XM_044310297.1 210 79 91 205 423 Q96AY4 1.12e-137 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31024 XM_044310297.1 210 79 91 205 423 Q96AY4 1.77e-123 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31025 XM_044310297.1 210 79 91 205 423 Q96AY4 2.74e-115 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31026 XM_044310297.1 210 79 91 205 423 Q96AY4 3.9e-101 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31027 XM_044310297.1 210 79 91 205 423 Q96AY4 3.2e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31028 XM_029350887.2 16 12 3 8 0 Q5ZLC6 1.31e-39 Ankyrin repeat domain-containing protein 10 Gallus gallus (Chicken) NA NA 31029 XM_044308872.1 0 1 5 8 0 NA NA NA NA NA NA 31030 XR_006397319.1 0 41 137 0 32 NA NA NA NA NA NA 31031 XM_029346229.2 308 355 72 281 316 NA NA NA NA NA NA 31032 XM_044311560.1 19 12 46 16 68 NA NA NA NA NA NA 31033 XM_044319437.1 24 0 8 7 46 NA NA NA NA NA NA 31034 XM_029337823.2 226 197 139 530 254 E1C2Z0 1.11e-129 Protein MMS22-like (Methyl methanesulfonate-sensitivity protein 22-like) Gallus gallus (Chicken) chromatin organization [GO:0006325]; double-strand break repair via homologous recombination [GO:0000724]; replication fork processing [GO:0031297] GO:0000724; GO:0003697; GO:0006325; GO:0031297; GO:0043596; GO:0090734 31035 XM_044321546.1 0 20 0 0 0 NA NA NA NA NA NA 31036 XM_029338660.2 0 1 0 1 13 NA NA NA NA NA NA 31037 XM_044317190.1 0 0 14 3 0 Q0VBU9 1.31e-27 Phospholipid phosphatase 4 (EC 3.1.3.4) (EC 3.6.1.75) Mus musculus (Mouse) blastocyst hatching [GO:0001835]; phospholipid dephosphorylation [GO:0046839]; phospholipid metabolic process [GO:0006644]; regulation of calcium ion import [GO:0090279] GO:0000810; GO:0001835; GO:0006644; GO:0008195; GO:0016020; GO:0042802; GO:0046839; GO:0090279 31038 XM_029344323.2 546 1004 231 592 236 A2VDD2 5.72e-34 Dynein light chain Tctex-type 5-B (Tctex1 domain-containing protein 1-B) Xenopus laevis (African clawed frog) NA NA 31039 XM_029330635.2 1067 187 184 1275 185 NA NA NA NA NA NA 31040 XM_029327860.2 11 10 36 6 48 NA NA NA NA NA NA 31041 XM_044328645.1 0 46 0 92 0 P46023 2.42e-115 G-protein coupled receptor GRL101 Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004930; GO:0005886 31042 XM_044323034.1 74 0 0 0 0 NA NA NA NA NA NA 31043 XM_044328596.1 0 9 0 0 0 NA NA NA NA NA NA 31044 XM_029336585.2 6 0 12 25 46 Q68FR8 0 Tubulin alpha-3 chain (EC 3.6.5.-) (Alpha-tubulin 3) [Cleaved into: Detyrosinated tubulin alpha-3 chain] Rattus norvegicus (Rat) microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278] GO:0000226; GO:0000278; GO:0005200; GO:0005525; GO:0005737; GO:0005874; GO:0016787; GO:0036064; GO:0046872 31045 XM_029341936.2 1014 922 724 563 491 Q08DK7 1.18e-99 Mitochondrial basic amino acids transporter (Carnitine/acylcarnitine translocase-like) (CACT-like) (Mitochondrial carnitine/acylcarnitine carrier protein CACL) (Mitochondrial ornithine transporter 3) (Solute carrier family 25 member 29) Bos taurus (Bovine) acyl carnitine transport [GO:0006844]; L-arginine transmembrane transport [GO:1903826]; L-histidine transmembrane transport [GO:0089709]; L-lysine transmembrane transport [GO:1903401]; mitochondrial L-ornithine transmembrane transport [GO:1990575]; ornithine transport [GO:0015822] GO:0005289; GO:0005292; GO:0005739; GO:0005743; GO:0006844; GO:0015174; GO:0015822; GO:0022857; GO:0089709; GO:1903401; GO:1903826; GO:1990575 31046 XM_029357298.2 0 0 1 0 10 NA NA NA NA NA NA 31047 XM_029335692.2 6 7 0 0 0 Q5RCP8 9.06e-60 Histone H2B type 2-E (H2B-clustered histone 21) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) defense response to bacterium [GO:0042742] GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0042742; GO:0046982 31048 XM_029346374.2 390 0 280 96 172 Q5FYB0 6.4e-133 Arylsulfatase J (ASJ) (EC 3.1.6.-) Homo sapiens (Human) NA GO:0004065; GO:0005576; GO:0005788; GO:0015629; GO:0046872 31049 XM_029348701.2 149 188 108 87 324 Q7ZX53 2.56e-84 Solute carrier family 22 member 15-like Xenopus laevis (African clawed frog) ion transport [GO:0006811] GO:0006811; GO:0016020; GO:0022857 31050 XM_044324961.1 3 0 0 13 0 P81274 1.59e-31 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 31051 XM_044324961.1 3 0 0 13 0 P81274 8.48e-27 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 31052 XM_044324961.1 3 0 0 13 0 P81274 1.04e-25 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 31053 XM_044328012.1 0 90 0 0 44 Q96DB5 2.83e-69 Regulator of microtubule dynamics protein 1 (RMD-1) (hRMD-1) (Protein FAM82B) Homo sapiens (Human) attachment of mitotic spindle microtubules to kinetochore [GO:0051315]; mitotic spindle organization [GO:0007052] GO:0005737; GO:0005876; GO:0007052; GO:0008017; GO:0051315; GO:0097431 31054 XM_044308002.1 1 0 0 16 15 NA NA NA NA NA NA 31055 XM_029352428.2 1481 879 532 522 774 NA NA NA NA NA NA 31056 XM_044328022.1 13 0 3 0 48 NA NA NA NA NA NA 31057 XM_029330711.2 47 25 37 34 186 A1L3F5 2.47e-103 C-Maf-inducing protein (c-Mip) Xenopus laevis (African clawed frog) NA GO:0005634; GO:0005737 31058 XM_029330711.2 47 25 37 34 186 A1L3F5 2.6e-87 C-Maf-inducing protein (c-Mip) Xenopus laevis (African clawed frog) NA GO:0005634; GO:0005737 31059 XM_044307236.1 7 3 29 391 204 Q7M456 2.24e-34 Ribonuclease Oy (RNase Oy) (EC 3.1.27.-) Crassostrea gigas (Pacific oyster) (Crassostrea angulata) NA GO:0003723; GO:0005576; GO:0033897 31060 XM_029344320.2 2 2 8 0 44 NA NA NA NA NA NA 31061 XM_029349346.2 692 585 322 584 488 A7RX34 4.41e-96 THO complex subunit 7 homolog Nematostella vectensis (Starlet sea anemone) mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397] GO:0000445; GO:0005737; GO:0006397; GO:0006406; GO:0016607 31062 XR_006397897.1 247 0 11 156 19 NA NA NA NA NA NA 31063 XM_044323592.1 90 45 0 163 391 NA NA NA NA NA NA 31064 XM_029331184.2 1256 1508 1429 1455 2944 Q92734 1.37e-51 Protein TFG (TRK-fused gene protein) Homo sapiens (Human) COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123] GO:0005737; GO:0005829; GO:0006888; GO:0042802; GO:0043123; GO:0043231; GO:0048208; GO:0070971 31065 XM_044323008.1 201 216 175 253 304 B8UU78 0 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 31066 XR_006391795.1 231 52 122 88 163 NA NA NA NA NA NA 31067 XR_006396317.1 365 172 764 174 1067 NA NA NA NA NA NA 31068 XM_044312759.1 28 58 9 39 18 A4IGM4 1.77e-58 Hydroxysteroid 11-beta-dehydrogenase 1-like protein (EC 1.1.1.-) (11-beta-hydroxysteroid dehydrogenase type 3) (11-DH3) (11-beta-HSD3) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005576; GO:0016491 31069 XM_044324948.1 173 42 49 117 167 Q6AZB8 4.97e-48 Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0004518; GO:0005634; GO:0005737; GO:0046872 31070 XR_006392313.1 17 14 10 28 0 NA NA NA NA NA NA 31071 XM_029331658.2 1144 729 664 949 1076 Q9BZI7 5.88e-36 Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (Up-frameshift suppressor 3 homolog on chromosome X) (hUpf3p-X) Homo sapiens (Human) brain development [GO:0007420]; mRNA transport [GO:0051028]; neuron projection development [GO:0031175]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of translation [GO:0045727] GO:0000184; GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0007420; GO:0031175; GO:0034451; GO:0035145; GO:0043025; GO:0045666; GO:0045727; GO:0051028 31072 XM_029358689.2 21 30 32 29 64 NA NA NA NA NA NA 31073 XR_003827614.2 12 4 30 18 23 NA NA NA NA NA NA 31074 XM_029333717.2 367 262 139 345 340 Q9U518 3.08e-167 L-asparaginase (EC 3.5.1.1) (DiAsp) (L-asparagine amidohydrolase) Dirofilaria immitis (Canine heartworm) asparagine metabolic process [GO:0006528] GO:0004067; GO:0006528 31075 XM_029336068.2 86 79 102 124 119 Q8R1C6 1.75e-64 Methyltransferase-like protein 22 (EC 2.1.1.-) Mus musculus (Mouse) protein methylation [GO:0006479] GO:0005634; GO:0005654; GO:0005730; GO:0006479; GO:0008276; GO:0018024; GO:0031072; GO:0032991 31076 XM_044326200.1 8 9 0 4 3 NA NA NA NA NA NA 31077 XR_006391976.1 54 25 120 7 15 NA NA NA NA NA NA 31078 XM_029337259.2 217 101 114 307 415 Q68EF4 7.11e-21 Metabotropic glutamate receptor 4 (mGluR4) Mus musculus (Mouse) adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway [GO:0007196]; chemical synaptic transmission [GO:0007268]; G protein-coupled glutamate receptor signaling pathway [GO:0007216]; learning [GO:0007612]; positive regulation of MAPK cascade [GO:0043410]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of synaptic transmission, glutamatergic [GO:0051966] GO:0001640; GO:0001642; GO:0004930; GO:0005516; GO:0005886; GO:0007196; GO:0007216; GO:0007268; GO:0007612; GO:0008066; GO:0031410; GO:0043005; GO:0043195; GO:0043198; GO:0043410; GO:0048306; GO:0048787; GO:0051966; GO:0098688; GO:0098978; GO:0099171; GO:0150048 31079 XM_029329892.2 680 573 409 723 746 Q17QQ2 3.4e-36 Thiopurine S-methyltransferase (EC 2.1.1.67) (Thiopurine methyltransferase) Bos taurus (Bovine) methylation [GO:0032259]; xenobiotic metabolic process [GO:0006805] GO:0005737; GO:0006805; GO:0008119; GO:0032259; GO:1904047 31080 XM_044321693.1 0 19 262 5 0 Q63415 8.05e-112 Proprotein convertase subtilisin/kexin type 6 (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin-like proprotein convertase 4) (SPC4) (Subtilisin/kexin-like protease PACE4) Rattus norvegicus (Rat) determination of left/right symmetry [GO:0007368]; glycoprotein metabolic process [GO:0009100]; nerve growth factor production [GO:0032902]; peptide hormone processing [GO:0016486]; protein processing [GO:0016485]; secretion by cell [GO:0032940]; zygotic determination of anterior/posterior axis, embryo [GO:0007354] GO:0004175; GO:0004252; GO:0005615; GO:0007354; GO:0007368; GO:0008201; GO:0009100; GO:0009986; GO:0016020; GO:0016485; GO:0016486; GO:0032902; GO:0032940; GO:0048406; GO:0062023 31081 XM_029355983.2 23 0 0 28 0 NA NA NA NA NA NA 31082 XM_029357367.2 330 285 208 304 442 Q28DT7 0 Polycomb protein eed Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) chromatin organization [GO:0006325] GO:0006325; GO:0035098 31083 XM_029337314.2 6 0 0 10 18 B4E2M5 1.79e-31 Ankyrin repeat domain-containing protein 66 Homo sapiens (Human) NA NA 31084 XR_006394951.1 4787 2019 2469 3432 2486 NA NA NA NA NA NA 31085 XM_044307957.1 0 0 0 10 0 NA NA NA NA NA NA 31086 XR_006392606.1 0 22 0 2 9 NA NA NA NA NA NA 31087 XR_006392729.1 0 0 3 13 0 NA NA NA NA NA NA 31088 XM_044314624.1 87 76 52 2 2 NA NA NA NA NA NA 31089 XM_029326847.2 246 212 157 166 176 NA NA NA NA NA NA 31090 XM_044328058.1 16 16 3 8 30 Q6LAF1 9.73e-52 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 31091 XM_029338230.2 166 450 244 410 325 NA NA NA NA NA NA 31092 XM_029325777.2 279 64 98 145 179 NA NA NA NA NA NA 31093 XM_044328167.1 0 11 0 0 3 NA NA NA NA NA NA 31094 XM_044318203.1 257 149 111 184 255 P49746 2.91e-108 Thrombospondin-3 Homo sapiens (Human) bone trabecula formation [GO:0060346]; cell-matrix adhesion [GO:0007160]; growth plate cartilage development [GO:0003417]; ossification involved in bone maturation [GO:0043931] GO:0003417; GO:0005509; GO:0005576; GO:0007160; GO:0008201; GO:0043931; GO:0048471; GO:0060346; GO:0062023 31095 XR_006397847.1 47 150 162 85 117 NA NA NA NA NA NA 31096 XM_029334537.2 13 5 0 14 4 NA NA NA NA NA NA 31097 XM_029351170.2 63 29 107 88 191 NA NA NA NA NA NA 31098 XM_044309690.1 161 62 14 12 584 NA NA NA NA NA NA 31099 XM_029329224.2 1039 930 752 1038 1307 Q9EQU5 1.58e-74 Protein SET (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A) (Template-activating factor I) (TAF-I) Mus musculus (Mouse) negative regulation of neuron apoptotic process [GO:0043524]; nucleosome assembly [GO:0006334] GO:0000785; GO:0003677; GO:0003682; GO:0005634; GO:0005654; GO:0005737; GO:0005783; GO:0005811; GO:0005829; GO:0006334; GO:0032991; GO:0042393; GO:0043524; GO:0048471 31100 XM_044308907.1 3 7 3 14 1 NA NA NA NA NA NA 31101 XM_029343582.2 840 910 266 822 1182 Q7ZYA2 1.61e-60 Transcription initiation factor TFIID subunit 8 (TBP-associated factor 8) Xenopus laevis (African clawed frog) cell differentiation [GO:0030154] GO:0005669; GO:0005737; GO:0030154; GO:0046982 31102 XM_044327340.1 24 19 29 80 9 NA NA NA NA NA NA 31103 XM_029358755.2 426 388 375 305 193 Q8BTM8 6.15e-32 Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin) Mus musculus (Mouse) actin crosslink formation [GO:0051764]; actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; angiogenesis [GO:0001525]; blood coagulation, intrinsic pathway [GO:0007597]; blood vessel remodeling [GO:0001974]; cell-cell junction organization [GO:0045216]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; early endosome to late endosome transport [GO:0045022]; epithelial to mesenchymal transition [GO:0001837]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; heart morphogenesis [GO:0003007]; megakaryocyte development [GO:0035855]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of axon regeneration [GO:0048680]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of platelet activation [GO:0010572]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; release of sequestered calcium ion into cytosol [GO:0051209]; semaphorin-plexin signaling pathway [GO:0071526]; synapse organization [GO:0050808]; tubulin deacetylation [GO:0090042]; wound healing, spreading of cells [GO:0044319] GO:0001525; GO:0001664; GO:0001837; GO:0001974; GO:0003007; GO:0003779; GO:0005080; GO:0005634; GO:0005730; GO:0005737; GO:0005802; GO:0005829; GO:0005884; GO:0005886; GO:0005903; GO:0005911; GO:0005938; GO:0007195; GO:0007597; GO:0010572; GO:0010977; GO:0015459; GO:0015629; GO:0016479; GO:0019900; GO:0021943; GO:0030018; GO:0030036; GO:0030334; GO:0030426; GO:0030863; GO:0031267; GO:0031523; GO:0031532; GO:0031852; GO:0032231; GO:0032233; GO:0032432; GO:0034394; GO:0034988; GO:0035855; GO:0042177; GO:0042307; GO:0042789; GO:0042803; GO:0043025; GO:0043066; GO:0043113; GO:0043123; GO:0043198; GO:0043204; GO:0043433; GO:0044295; GO:0044319; GO:0044325; GO:0044877; GO:0045022; GO:0045184; GO:0045216; GO:0046332; GO:0048471; GO:0048680; GO:0050808; GO:0050821; GO:0051015; GO:0051020; GO:0051209; GO:0051220; GO:0051764; GO:0060271; GO:0071526; GO:0072659; GO:0090042; GO:0090307; GO:0097368; GO:0097440; GO:0098794; GO:0098978; GO:0140297; GO:1900026; GO:1901381; GO:1902396; GO:1905000; GO:1905031; GO:1990779; GO:2000179; GO:2001046; GO:2001224 31104 XR_006396296.1 0 0 1 3 8 NA NA NA NA NA NA 31105 XM_029338627.2 0 316 116 0 119 NA NA NA NA NA NA 31106 XM_044327334.1 84 1 82 69 96 NA NA NA NA NA NA 31107 XR_006393501.1 177 27 169 113 210 NA NA NA NA NA NA 31108 XM_044315870.1 91 94 40 0 0 NA NA NA NA NA NA 31109 XM_029348910.2 547 0 0 381 0 NA NA NA NA NA NA 31110 XM_029336676.2 423 190 139 447 331 F1RWC3 8.57e-28 Cubilin (Intrinsic factor-cobalamin receptor) Sus scrofa (Pig) cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031] GO:0005509; GO:0005765; GO:0005768; GO:0005905; GO:0008203; GO:0015031; GO:0016324; GO:0031419 31111 XM_029336676.2 423 190 139 447 331 F1RWC3 2.07e-25 Cubilin (Intrinsic factor-cobalamin receptor) Sus scrofa (Pig) cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031] GO:0005509; GO:0005765; GO:0005768; GO:0005905; GO:0008203; GO:0015031; GO:0016324; GO:0031419 31112 XM_029336676.2 423 190 139 447 331 F1RWC3 5.68e-25 Cubilin (Intrinsic factor-cobalamin receptor) Sus scrofa (Pig) cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031] GO:0005509; GO:0005765; GO:0005768; GO:0005905; GO:0008203; GO:0015031; GO:0016324; GO:0031419 31113 XM_029336676.2 423 190 139 447 331 F1RWC3 1.49e-24 Cubilin (Intrinsic factor-cobalamin receptor) Sus scrofa (Pig) cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031] GO:0005509; GO:0005765; GO:0005768; GO:0005905; GO:0008203; GO:0015031; GO:0016324; GO:0031419 31114 XM_029336676.2 423 190 139 447 331 F1RWC3 3.15e-23 Cubilin (Intrinsic factor-cobalamin receptor) Sus scrofa (Pig) cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031] GO:0005509; GO:0005765; GO:0005768; GO:0005905; GO:0008203; GO:0015031; GO:0016324; GO:0031419 31115 XM_029337188.2 156 405 288 78 437 NA NA NA NA NA NA 31116 XM_044322010.1 355 190 140 218 145 P59910 1.44e-137 DnaJ homolog subfamily B member 13 (Testis and spermatogenesis cell-related protein 6) (Testis spermatocyte apoptosis-related gene 6 protein) (Testis spermatogenesis apoptosis-related gene 3 protein) (Testis spermatogenesis apoptosis-related gene 6 protein) Homo sapiens (Human) axonemal central apparatus assembly [GO:1904158]; chaperone cofactor-dependent protein refolding [GO:0051085] GO:0005829; GO:0005930; GO:0031514; GO:0036126; GO:0051082; GO:0051085; GO:0051087; GO:0097224; GO:1904158 31117 XM_044319951.1 1031 691 176 518 616 NA NA NA NA NA NA 31118 XR_006393419.1 10 0 3 0 7 Q6ZTW0 9.82e-29 Tubulin polyglutamylase complex subunit 1 (PGs1) Homo sapiens (Human) adult behavior [GO:0030534]; chemical synaptic transmission [GO:0007268]; protein polyglutamylation [GO:0018095]; sperm axoneme assembly [GO:0007288]; vesicle localization [GO:0051648] GO:0005737; GO:0005813; GO:0005874; GO:0007268; GO:0007288; GO:0008017; GO:0018095; GO:0030424; GO:0030425; GO:0030534; GO:0031514; GO:0045202; GO:0051648; GO:0070740 31119 XM_044318678.1 1208 512 766 1471 1289 Q6QNK2 8.54e-40 Adhesion G-protein coupled receptor D1 (G-protein coupled receptor 133) (G-protein coupled receptor PGR25) Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0005654; GO:0005886; GO:0007166; GO:0007186; GO:0007189; GO:0016020 31120 XM_029326876.2 115 46 59 113 224 NA NA NA NA NA NA 31121 XM_044317972.1 181 80 28 55 187 Q7TQH0 5.76e-28 Ataxin-2-like protein Mus musculus (Mouse) mRNA metabolic process [GO:0016071]; stress granule assembly [GO:0034063] GO:0003723; GO:0005829; GO:0010494; GO:0016020; GO:0016071; GO:0016607; GO:0034063 31122 XM_029348916.2 79 67 0 105 263 P95329 9.41e-107 Malate synthase (EC 2.3.3.9) Myxococcus xanthus (strain DK1622) glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099] GO:0004474; GO:0005737; GO:0006097; GO:0006099 31123 XM_029336360.2 901 570 272 668 587 O75715 1.38e-52 Epididymal secretory glutathione peroxidase (EC 1.11.1.9) (Epididymis-specific glutathione peroxidase-like protein) (EGLP) (Glutathione peroxidase 5) (GPx-5) (GSHPx-5) Homo sapiens (Human) cellular response to oxidative stress [GO:0034599]; lipid metabolic process [GO:0006629] GO:0004601; GO:0004602; GO:0005576; GO:0006629; GO:0034599 31124 XM_029342632.2 352 223 281 293 422 Q8NCL4 4.69e-163 Polypeptide N-acetylgalactosaminyltransferase 6 (EC 2.4.1.41) (Polypeptide GalNAc transferase 6) (GalNAc-T6) (pp-GaNTase 6) (Protein-UDP acetylgalactosaminyltransferase 6) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 6) Homo sapiens (Human) O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493]; protein O-linked glycosylation via threonine [GO:0018243] GO:0000139; GO:0004653; GO:0005794; GO:0006493; GO:0016266; GO:0018243; GO:0030246; GO:0046872; GO:0048471 31125 XR_003826400.2 907 1155 1516 1914 120 NA NA NA NA NA NA 31126 XM_029331879.2 793 612 451 692 710 Q8VCL5 5.89e-96 Solute carrier family 17 member 9 Mus musculus (Mouse) ADP transport [GO:0015866]; ATP export [GO:1904669]; ATP transport [GO:0015867]; exocytosis [GO:0006887]; guanine nucleotide transmembrane transport [GO:1903790] GO:0001409; GO:0005347; GO:0006887; GO:0015217; GO:0015866; GO:0015867; GO:0030141; GO:0042584; GO:1903790; GO:1904669 31127 XM_044313828.1 123 17 103 74 217 NA NA NA NA NA NA 31128 XM_044307965.1 0 7 7 10 2 Q96DM1 8.56e-49 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 31129 XM_029345272.2 38 11 39 80 83 NA NA NA NA NA NA 31130 XM_029329916.2 495 283 246 338 236 B8VIU6 8.03e-154 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 31131 XM_044326330.1 300 102 109 34 43 NA NA NA NA NA NA 31132 XM_029330579.2 638 725 598 874 832 D3ZH22 1.53e-35 Sugar transporter SWEET1 (RAG1-activating protein 1) (Solute carrier family 50 member 1) Rattus norvegicus (Rat) carbohydrate transport [GO:0008643] GO:0000139; GO:0005794; GO:0005886; GO:0008643; GO:0012505; GO:0016020; GO:0042947; GO:0051119 31133 XM_029358539.2 2274 1403 1167 2284 1582 Q5ZL26 2.68e-147 Phosphoribosyl pyrophosphate synthase-associated protein 2 (PRPP synthase-associated protein 2) Gallus gallus (Chicken) 5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; purine nucleotide biosynthetic process [GO:0006164] GO:0000287; GO:0002189; GO:0004749; GO:0005737; GO:0006015; GO:0006164 31134 XM_044315439.1 185 128 67 92 112 Q7RTR2 1.26e-50 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 31135 XM_044315439.1 185 128 67 92 112 Q7RTR2 1.73e-50 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 31136 XM_044315439.1 185 128 67 92 112 Q7RTR2 4.64e-49 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 31137 XM_029355180.2 0 35 22 502 0 Q15256 1.34e-76 Receptor-type tyrosine-protein phosphatase R (R-PTP-R) (EC 3.1.3.48) (Ch-1PTPase) (NC-PTPCOM1) (Protein-tyrosine phosphatase PCPTP1) Homo sapiens (Human) ERBB2 signaling pathway [GO:0038128]; in utero embryonic development [GO:0001701]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; signal transduction [GO:0007165] GO:0001701; GO:0004725; GO:0005001; GO:0005615; GO:0005829; GO:0005886; GO:0006470; GO:0007165; GO:0010633; GO:0019901; GO:0030054; GO:0035335; GO:0038128; GO:0048471; GO:0070373 31138 XM_029330292.2 7706 8012 2895 7393 6302 O08688 0 Calpain-5 (EC 3.4.22.-) (New calpain 3) (nCL-3) Mus musculus (Mouse) proteolysis [GO:0006508] GO:0004198; GO:0005737; GO:0006508; GO:0009986; GO:0045202 31139 XR_006394998.1 59 21 61 4 84 NA NA NA NA NA NA 31140 XR_006391751.1 519 428 158 697 452 NA NA NA NA NA NA 31141 XM_044320020.1 3 0 0 2 19 NA NA NA NA NA NA 31142 XM_044317275.1 34 24 39 8 87 NA NA NA NA NA NA 31143 XM_029326363.2 2 0 0 0 7 NA NA NA NA NA NA 31144 XM_044317554.1 228 148 208 194 372 NA NA NA NA NA NA 31145 XM_029328635.2 258 182 86 215 171 P35816 4.79e-59 [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial (PDP 1) (EC 3.1.3.43) (Protein phosphatase 2C) (Pyruvate dehydrogenase phosphatase catalytic subunit 1) (PDPC 1) Bos taurus (Bovine) dephosphorylation [GO:0016311]; positive regulation of pyruvate dehydrogenase activity [GO:1904184]; protein dephosphorylation [GO:0006470] GO:0000287; GO:0004722; GO:0004741; GO:0005509; GO:0005739; GO:0005759; GO:0006470; GO:0016311; GO:0019909; GO:1904184 31146 XM_044325603.1 2014 4164 715 2079 551 Q8BZ20 4.36e-59 Protein mono-ADP-ribosyltransferase PARP12 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 12) (ARTD12) (Poly [ADP-ribose] polymerase 12) (PARP-12) (Zinc finger CCCH domain-containing protein 1) Mus musculus (Mouse) protein auto-ADP-ribosylation [GO:0070213] GO:0003950; GO:0005634; GO:0016779; GO:0046872; GO:0070213; GO:0140803; GO:1990404 31147 XR_006392721.1 252 28 78 146 421 NA NA NA NA NA NA 31148 XR_003825050.2 0 0 0 0 15 NA NA NA NA NA NA 31149 XM_044328989.1 54 4 41 0 23 NA NA NA NA NA NA 31150 XM_044322771.1 2710 2887 1482 2248 2245 Q8VEE0 6.79e-80 Ribulose-phosphate 3-epimerase (EC 5.1.3.1) (Ribulose-5-phosphate-epimerase) Mus musculus (Mouse) carbohydrate metabolic process [GO:0005975]; cellular carbohydrate metabolic process [GO:0044262]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052] GO:0004750; GO:0005829; GO:0005975; GO:0006098; GO:0009052; GO:0030246; GO:0042802; GO:0042803; GO:0043231; GO:0044262; GO:0046872; GO:0048029 31151 XM_044308570.1 17 11 11 16 0 NA NA NA NA NA NA 31152 XM_029350821.2 48 5 58 20 3 Q5MPA9 1.83e-177 Serine/threonine-protein kinase DCLK2 (EC 2.7.11.1) (CaMK-like CREB regulatory kinase 2) (CL2) (CLICK-II) (CLICK2) (Doublecortin-like and CAM kinase-like 2) (Doublecortin-like kinase 2) Rattus norvegicus (Rat) hippocampus development [GO:0021766]; intracellular signal transduction [GO:0035556]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of protein localization to nucleus [GO:1900181]; peptidyl-serine phosphorylation [GO:0018105]; protein localization to nucleus [GO:0034504]; pyramidal neuron development [GO:0021860] GO:0000226; GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0005856; GO:0008017; GO:0018105; GO:0021766; GO:0021860; GO:0034504; GO:0035556; GO:0106310; GO:1900181 31153 XM_044316670.1 32 7 17 5 32 Q923J1 2.01e-106 Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Channel-kinase 1) (Long transient receptor potential channel 7) (LTrpC-7) (LTrpC7) (Transient receptor potential-phospholipase C-interacting kinase) (TRP-PLIK) Mus musculus (Mouse) actomyosin structure organization [GO:0031032]; calcium ion transport [GO:0006816]; calcium-dependent cell-matrix adhesion [GO:0016340]; cation transmembrane transport [GO:0098655]; cellular magnesium ion homeostasis [GO:0010961]; divalent inorganic cation homeostasis [GO:0072507]; memory [GO:0007613]; necroptotic process [GO:0070266]; positive regulation of apoptotic process [GO:0043065]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein tetramerization [GO:0051262] GO:0001726; GO:0003779; GO:0004672; GO:0004674; GO:0005261; GO:0005262; GO:0005524; GO:0005737; GO:0005886; GO:0006468; GO:0006816; GO:0007613; GO:0010961; GO:0016020; GO:0016301; GO:0016340; GO:0017022; GO:0030672; GO:0031032; GO:0043005; GO:0043025; GO:0043065; GO:0043196; GO:0046777; GO:0046872; GO:0051262; GO:0070266; GO:0072507; GO:0098655; GO:0106310 31154 XM_044320147.1 1702 1330 1018 1470 1315 Q6GP15 1.52e-50 Mediator of RNA polymerase II transcription subunit 25 (Mediator complex subunit 25) Xenopus laevis (African clawed frog) NA GO:0005634 31155 XM_044320147.1 1702 1330 1018 1470 1315 Q6GP15 1.72e-42 Mediator of RNA polymerase II transcription subunit 25 (Mediator complex subunit 25) Xenopus laevis (African clawed frog) NA GO:0005634 31156 XM_044318924.1 7082 6042 3727 7281 4005 O54857 6.28e-112 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (EC 3.1.3.16) (EC 3.1.3.48) (EC 3.1.3.67) (Phosphatase and tensin homolog) Rattus norvegicus (Rat) adult behavior [GO:0030534]; aging [GO:0007568]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; B cell proliferation [GO:0042100]; brain morphogenesis [GO:0048854]; canonical Wnt signaling pathway [GO:0060070]; cardiac muscle tissue development [GO:0048738]; cell migration [GO:0016477]; cell motility [GO:0048870]; cell population proliferation [GO:0008283]; cellular response to decreased oxygen levels [GO:0036294]; cellular response to electrical stimulus [GO:0071257]; cellular response to ethanol [GO:0071361]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to leptin stimulus [GO:0044320]; cellular response to nerve growth factor stimulus [GO:1990090]; central nervous system development [GO:0007417]; central nervous system myelin maintenance [GO:0032286]; central nervous system neuron axonogenesis [GO:0021955]; dendritic spine morphogenesis [GO:0060997]; dentate gyrus development [GO:0021542]; dephosphorylation [GO:0016311]; endothelial cell migration [GO:0043542]; forebrain morphogenesis [GO:0048853]; heart development [GO:0007507]; inositol phosphate dephosphorylation [GO:0046855]; learning or memory [GO:0007611]; locomotor rhythm [GO:0045475]; locomotory behavior [GO:0007626]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; male mating behavior [GO:0060179]; maternal behavior [GO:0042711]; memory [GO:0007613]; multicellular organismal response to stress [GO:0033555]; myelination [GO:0042552]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axon regeneration [GO:0048681]; negative regulation of axonogenesis [GO:0050771]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell cycle G1/S phase transition [GO:1902807]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of cellular senescence [GO:2000773]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of defense response to bacterium [GO:1900425]; negative regulation of dendrite extension [GO:1903860]; negative regulation of dendritic spine morphogenesis [GO:0061002]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of keratinocyte migration [GO:0051548]; negative regulation of myelination [GO:0031642]; negative regulation of neuron projection development [GO:0010977]; negative regulation of organ growth [GO:0046621]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of phagocytosis [GO:0050765]; negative regulation of phagocytosis, engulfment [GO:0060101]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of ribosome biogenesis [GO:0090071]; negative regulation of signaling receptor activity [GO:2000272]; negative regulation of synaptic vesicle clustering [GO:2000808]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of vascular associated smooth muscle cell proliferation [GO:1904706]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; neuron projection development [GO:0031175]; neuron-neuron synaptic transmission [GO:0007270]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol dephosphorylation [GO:0046856]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of TRAIL-activated apoptotic signaling pathway [GO:1903984]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; postsynaptic density assembly [GO:0097107]; prepulse inhibition [GO:0060134]; presynaptic membrane assembly [GO:0097105]; prostate gland growth [GO:0060736]; protein dephosphorylation [GO:0006470]; protein kinase B signaling [GO:0043491]; protein stabilization [GO:0050821]; regulation of axon regeneration [GO:0048679]; regulation of B cell apoptotic process [GO:0002902]; regulation of cell cycle [GO:0051726]; regulation of cellular component size [GO:0032535]; regulation of cellular localization [GO:0060341]; regulation of macrophage apoptotic process [GO:2000109]; regulation of myeloid cell apoptotic process [GO:0033032]; regulation of neuron projection development [GO:0010975]; regulation of protein kinase B signaling [GO:0051896]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to activity [GO:0014823]; response to arsenic-containing substance [GO:0046685]; response to ATP [GO:0033198]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to glucose [GO:0009749]; response to inorganic substance [GO:0010035]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to xenobiotic stimulus [GO:0009410]; response to zinc ion [GO:0010043]; rhythmic synaptic transmission [GO:0060024]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; synapse maturation [GO:0060074]; T cell proliferation [GO:0042098] GO:0001525; GO:0001933; GO:0002902; GO:0004438; GO:0004721; GO:0004722; GO:0004725; GO:0005161; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0005886; GO:0006470; GO:0006915; GO:0007270; GO:0007416; GO:0007417; GO:0007507; GO:0007568; GO:0007584; GO:0007611; GO:0007613; GO:0007626; GO:0008138; GO:0008283; GO:0008284; GO:0008285; GO:0009410; GO:0009749; GO:0009898; GO:0010033; GO:0010035; GO:0010043; GO:0010628; GO:0010666; GO:0010719; GO:0010975; GO:0010977; GO:0010997; GO:0014065; GO:0014069; GO:0014070; GO:0014823; GO:0016311; GO:0016314; GO:0016324; GO:0016477; GO:0016605; GO:0016791; GO:0017018; GO:0019899; GO:0019901; GO:0021542; GO:0021955; GO:0030165; GO:0030336; GO:0030534; GO:0030889; GO:0031175; GO:0031642; GO:0031647; GO:0032228; GO:0032286; GO:0032355; GO:0032535; GO:0032869; GO:0033032; GO:0033137; GO:0033198; GO:0033555; GO:0035176; GO:0035255; GO:0035749; GO:0036294; GO:0042098; GO:0042100; GO:0042130; GO:0042552; GO:0042711; GO:0042802; GO:0042995; GO:0043005; GO:0043065; GO:0043066; GO:0043197; GO:0043220; GO:0043491; GO:0043542; GO:0044320; GO:0045211; GO:0045471; GO:0045475; GO:0045666; GO:0045736; GO:0045786; GO:0045792; GO:0046621; GO:0046685; GO:0046855; GO:0046856; GO:0048008; GO:0048679; GO:0048681; GO:0048738; GO:0048853; GO:0048854; GO:0048870; GO:0050680; GO:0050765; GO:0050771; GO:0050821; GO:0051091; GO:0051548; GO:0051717; GO:0051726; GO:0051800; GO:0051895; GO:0051896; GO:0051898; GO:0060024; GO:0060044; GO:0060070; GO:0060074; GO:0060101; GO:0060134; GO:0060179; GO:0060291; GO:0060292; GO:0060341; GO:0060736; GO:0060997; GO:0061002; GO:0070373; GO:0070374; GO:0071257; GO:0071361; GO:0071456; GO:0090071; GO:0090394; GO:0097105; GO:0097107; GO:0099524; GO:1900425; GO:1901017; GO:1902807; GO:1903690; GO:1903860; GO:1903984; GO:1904668; GO:1904706; GO:1990090; GO:1990314; GO:1990381; GO:1990782; GO:2000060; GO:2000109; GO:2000134; GO:2000272; GO:2000463; GO:2000773; GO:2000808; GO:2001235 31157 XM_029328767.2 37 0 24 54 23 Q28615 1.62e-151 Solute carrier family 13 member 2 (Na(+)/dicarboxylate cotransporter 1) (NaDC-1) (Renal sodium/dicarboxylate cotransporter) Oryctolagus cuniculus (Rabbit) alpha-ketoglutarate transport [GO:0015742]; fumarate transport [GO:0015741]; succinate transmembrane transport [GO:0071422] GO:0015138; GO:0015139; GO:0015141; GO:0015741; GO:0015742; GO:0016324; GO:0017153; GO:0071422 31158 XM_029355705.2 73 83 116 62 118 NA NA NA NA NA NA 31159 XM_044324304.1 2768 0 363 2568 327 P49961 8.16e-48 Ectonucleoside triphosphate diphosphohydrolase 1 (NTPDase 1) (EC 3.6.1.5) (Ecto-ATP diphosphohydrolase 1) (Ecto-ATPDase 1) (Ecto-ATPase 1) (Ecto-apyrase) (Lymphoid cell activation antigen) (CD antigen CD39) Homo sapiens (Human) blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; nucleoside diphosphate catabolic process [GO:0009134] GO:0004382; GO:0005524; GO:0005886; GO:0007155; GO:0007596; GO:0009134; GO:0016020; GO:0017110; GO:0045134; GO:0070062 31160 XM_029343366.2 5551 4104 5851 5175 5928 A7RM45 0 Probable lysosomal cobalamin transporter Nematostella vectensis (Starlet sea anemone) protein localization to vacuole [GO:0072665] GO:0005765; GO:0005774; GO:0031419; GO:0072665 31161 XM_044318097.1 0 2 2 0 503 NA NA NA NA NA NA 31162 XM_029331913.2 76 74 0 0 78 Q8TC84 5.82e-95 Fibronectin type 3 and ankyrin repeat domains protein 1 Homo sapiens (Human) negative regulation of apoptotic process [GO:0043066]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of apoptotic process [GO:0042981] GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005929; GO:0036064; GO:0042981; GO:0043065; GO:0043066; GO:0045893; GO:0051091; GO:0097546 31163 XM_029330342.2 479 0 0 0 136 Q924A2 1.71e-40 Protein capicua homolog Mus musculus (Mouse) brain development [GO:0007420]; learning [GO:0007612]; lung alveolus development [GO:0048286]; memory [GO:0007613]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357]; social behavior [GO:0035176]; transcription by RNA polymerase II [GO:0006366] GO:0000122; GO:0000977; GO:0000981; GO:0003682; GO:0005634; GO:0005654; GO:0006357; GO:0006366; GO:0007420; GO:0007612; GO:0007613; GO:0032991; GO:0035176; GO:0043231; GO:0045892; GO:0048286 31164 XM_029330342.2 479 0 0 0 136 Q924A2 2.14e-21 Protein capicua homolog Mus musculus (Mouse) brain development [GO:0007420]; learning [GO:0007612]; lung alveolus development [GO:0048286]; memory [GO:0007613]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357]; social behavior [GO:0035176]; transcription by RNA polymerase II [GO:0006366] GO:0000122; GO:0000977; GO:0000981; GO:0003682; GO:0005634; GO:0005654; GO:0006357; GO:0006366; GO:0007420; GO:0007612; GO:0007613; GO:0032991; GO:0035176; GO:0043231; GO:0045892; GO:0048286 31165 XM_029328797.2 520 192 377 129 0 Q14184 3.77e-95 Double C2-like domain-containing protein beta (Doc2-beta) Homo sapiens (Human) calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-dependent activation of synaptic vesicle fusion [GO:0099502]; exocytosis [GO:0006887]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of insulin secretion [GO:0032024]; positive regulation of vesicle fusion [GO:0031340]; protein localization [GO:0008104]; regulation of calcium ion-dependent exocytosis [GO:0017158]; spontaneous neurotransmitter secretion [GO:0061669] GO:0005509; GO:0005544; GO:0005737; GO:0005886; GO:0006887; GO:0008104; GO:0017158; GO:0019905; GO:0031340; GO:0032024; GO:0045202; GO:0045956; GO:0048791; GO:0061669; GO:0098793; GO:0099502 31166 XM_044313612.1 67 9 45 0 49 NA NA NA NA NA NA 31167 XM_029323720.2 0 0 0 538 0 P25931 4.64e-28 RYamide receptor (Neuropeptide Y-like receptor) (NPY-R) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218] GO:0001653; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0016020 31168 XM_044323249.1 3 9 0 24 28 NA NA NA NA NA NA 31169 XM_044322215.1 0 3 6 0 0 NA NA NA NA NA NA 31170 XR_006393073.1 41 2 25 5 151 NA NA NA NA NA NA 31171 XR_003826177.2 54 0 8 0 19 NA NA NA NA NA NA 31172 XM_029356408.2 0 24 0 0 39 Q9NRM2 1.23e-118 Zinc finger protein 277 (Nuclear receptor-interacting factor 4) Homo sapiens (Human) cellular response to hydrogen peroxide [GO:0070301]; regulation of cellular senescence [GO:2000772] GO:0000978; GO:0005634; GO:0046872; GO:0070301; GO:2000772 31173 XM_029350228.2 0 0 0 13 92 O43182 7.45e-58 Rho GTPase-activating protein 6 (Rho-type GTPase-activating protein 6) (Rho-type GTPase-activating protein RhoGAPX-1) Homo sapiens (Human) actin filament polymerization [GO:0030041]; activation of phospholipase C activity [GO:0007202]; focal adhesion assembly [GO:0048041]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of stress fiber assembly [GO:0051497]; positive regulation of GTPase activity [GO:0043547]; positive regulation of phospholipase activity [GO:0010518]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266] GO:0005096; GO:0005737; GO:0005829; GO:0005884; GO:0007202; GO:0007266; GO:0010518; GO:0015629; GO:0016004; GO:0017124; GO:0030041; GO:0043274; GO:0043547; GO:0048041; GO:0051056; GO:0051497; GO:0051895 31174 XM_029347376.2 36 20 0 243 205 NA NA NA NA NA NA 31175 XM_044325967.1 356 508 376 708 680 NA NA NA NA NA NA 31176 XM_029329098.2 787 0 0 0 0 Q96242 5.36e-29 Allene oxide synthase, chloroplastic (EC 4.2.1.92) (Cytochrome P450 74A) (Hydroperoxide dehydrase) Arabidopsis thaliana (Mouse-ear cress) defense response [GO:0006952]; defense response to fungus [GO:0050832]; epoxygenase P450 pathway [GO:0019373]; fatty acid biosynthetic process [GO:0006633]; jasmonic acid biosynthetic process [GO:0009695]; oxylipin biosynthetic process [GO:0031408]; oxylipin metabolic process [GO:0031407]; response to fungus [GO:0009620]; response to jasmonic acid [GO:0009753]; response to wounding [GO:0009611]; sterol metabolic process [GO:0016125] GO:0004497; GO:0005506; GO:0005739; GO:0006633; GO:0006952; GO:0009507; GO:0009534; GO:0009535; GO:0009536; GO:0009579; GO:0009611; GO:0009620; GO:0009695; GO:0009753; GO:0009941; GO:0009978; GO:0010287; GO:0016125; GO:0016491; GO:0016705; GO:0019373; GO:0019825; GO:0020037; GO:0031407; GO:0031408; GO:0050832 31177 XM_029338893.2 180 560 90 318 225 Q5RAS8 1.26e-29 Transmembrane protein 199 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cellular iron ion homeostasis [GO:0006879]; cellular response to increased oxygen levels [GO:0036295]; lysosomal lumen acidification [GO:0007042]; lysosomal protein catabolic process [GO:1905146]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072] GO:0005764; GO:0005783; GO:0005789; GO:0006879; GO:0007042; GO:0016471; GO:0030663; GO:0033116; GO:0036295; GO:0070072; GO:1905146 31178 XM_029342340.2 730 696 619 861 1024 NA NA NA NA NA NA 31179 XM_029328636.2 18 20 2 19 10 Q5ZKI0 2.92e-90 Calcium/calmodulin-dependent protein kinase type II delta chain (CaM kinase II subunit delta) (CaM-kinase II delta chain) (CaMK-II subunit delta) (EC 2.7.11.17) Gallus gallus (Chicken) protein phosphorylation [GO:0006468] GO:0004683; GO:0005516; GO:0005524; GO:0005737; GO:0006468; GO:0043005; GO:0106310 31180 XM_044314855.1 138 5 89 66 252 NA NA NA NA NA NA 31181 XM_044325428.1 41 0 91 23 114 NA NA NA NA NA NA 31182 XR_006394420.1 335 119 131 232 191 Q5R6J1 4.12e-125 Sodium-dependent neutral amino acid transporter B(0)AT1 (Solute carrier family 6 member 19) (System B(0) neutral amino acid transporter AT1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0015175; GO:0015293; GO:0016324 31183 XR_006394420.1 335 119 131 232 191 Q5R6J1 4.12e-125 Sodium-dependent neutral amino acid transporter B(0)AT1 (Solute carrier family 6 member 19) (System B(0) neutral amino acid transporter AT1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0015175; GO:0015293; GO:0016324 31184 XM_044308753.1 0 0 0 0 141 NA NA NA NA NA NA 31185 XM_044322451.1 0 0 0 0 13 NA NA NA NA NA NA 31186 XM_029335414.2 527 359 343 427 319 NA NA NA NA NA NA 31187 XM_044326199.1 89 75 71 76 53 NA NA NA NA NA NA 31188 XM_044321021.1 34 15 7 36 14 NA NA NA NA NA NA 31189 XM_044324690.1 274 266 450 382 116 A2AJ76 1.13e-46 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 31190 XM_044324690.1 274 266 450 382 116 A2AJ76 4.4e-43 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 31191 XM_044324690.1 274 266 450 382 116 A2AJ76 5.24e-42 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 31192 XM_044324690.1 274 266 450 382 116 A2AJ76 5.4e-41 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 31193 XM_044324690.1 274 266 450 382 116 A2AJ76 7.02e-41 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 31194 XM_044324690.1 274 266 450 382 116 A2AJ76 9.94e-38 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 31195 XM_044324690.1 274 266 450 382 116 A2AJ76 1.06e-37 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 31196 XM_044324690.1 274 266 450 382 116 A2AJ76 3.43e-37 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 31197 XM_044324690.1 274 266 450 382 116 A2AJ76 6.49e-37 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 31198 XM_044324690.1 274 266 450 382 116 A2AJ76 9.75e-37 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 31199 XM_044324690.1 274 266 450 382 116 A2AJ76 9.38e-36 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 31200 XM_044324690.1 274 266 450 382 116 A2AJ76 9.02e-35 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 31201 XM_044324690.1 274 266 450 382 116 A2AJ76 1.16e-33 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 31202 XM_044324690.1 274 266 450 382 116 A2AJ76 2.32e-33 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 31203 XM_044324690.1 274 266 450 382 116 A2AJ76 2.4e-30 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 31204 XM_044324690.1 274 266 450 382 116 A2AJ76 4.88e-30 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 31205 XM_044324690.1 274 266 450 382 116 A2AJ76 5.53e-29 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 31206 XM_044324690.1 274 266 450 382 116 A2AJ76 5.91e-29 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 31207 XM_029330208.2 15 0 1 374 0 Q9TU19 6.72e-121 Nephrocystin-1 Canis lupus familiaris (Dog) (Canis familiaris) cell differentiation [GO:0030154]; cell projection organization [GO:0030030]; protein localization involved in establishment of planar polarity [GO:0090251]; spermatogenesis [GO:0007283] GO:0005737; GO:0005856; GO:0005911; GO:0005912; GO:0005923; GO:0005929; GO:0007283; GO:0030030; GO:0030154; GO:0090251 31208 XM_029338859.2 3225 1718 2125 3412 3922 Q5RD26 7.55e-66 Heterogeneous nuclear ribonucleoprotein H2 (hnRNP H2) (Heterogeneous nuclear ribonucleoprotein H') (hnRNP H') [Cleaved into: Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed] Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003723; GO:0005654; GO:1990904 31209 XM_029336800.2 12 0 0 3 7 Q4UMH6 1.45e-31 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 31210 XR_006397042.1 13 0 0 0 0 NA NA NA NA NA NA 31211 XM_029351868.2 57 45 23 62 20 NA NA NA NA NA NA 31212 XR_006396249.1 1134 222 177 480 372 NA NA NA NA NA NA 31213 XR_006393335.1 949 764 405 843 1463 Q8T062 5.38e-26 Neprilysin-4 (EC 3.4.24.11) Drosophila melanogaster (Fruit fly) protein processing [GO:0016485]; proteolysis [GO:0006508] GO:0004175; GO:0004222; GO:0005615; GO:0005886; GO:0006508; GO:0008237; GO:0016020; GO:0016485; GO:0016529; GO:0046872 31214 XM_044317550.1 0 0 0 31 55 NA NA NA NA NA NA 31215 XM_044315091.1 311 450 225 514 245 Q6NZJ6 3.63e-98 Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G 1) (eIF-4G1) Mus musculus (Mouse) behavioral fear response [GO:0001662]; cellular macromolecule biosynthetic process [GO:0034645]; cellular response to nutrient levels [GO:0031669]; energy homeostasis [GO:0097009]; lung development [GO:0030324]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of autophagy [GO:0010507]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; neuron differentiation [GO:0030182]; positive regulation of cell death [GO:0010942]; positive regulation of cell growth [GO:0030307]; positive regulation of eukaryotic translation initiation factor 4F complex assembly [GO:1905537]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of mRNA cap binding [GO:1905612]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of translation in response to endoplasmic reticulum stress [GO:0036493]; regulation of polysome binding [GO:1905696]; regulation of presynapse assembly [GO:1905606]; regulation of translational initiation [GO:0006446]; response to ethanol [GO:0045471]; translation [GO:0006412]; translational initiation [GO:0006413] GO:0001662; GO:0003729; GO:0003743; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0005844; GO:0006412; GO:0006413; GO:0006446; GO:0008135; GO:0008190; GO:0010494; GO:0010507; GO:0010801; GO:0010942; GO:0016281; GO:0030182; GO:0030307; GO:0030324; GO:0031669; GO:0033138; GO:0034645; GO:0035278; GO:0036493; GO:0042802; GO:0045471; GO:0045666; GO:0051247; GO:0097009; GO:0098794; GO:1900087; GO:1905537; GO:1905606; GO:1905612; GO:1905696 31216 XM_044315091.1 311 450 225 514 245 Q6NZJ6 2.17e-56 Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G 1) (eIF-4G1) Mus musculus (Mouse) behavioral fear response [GO:0001662]; cellular macromolecule biosynthetic process [GO:0034645]; cellular response to nutrient levels [GO:0031669]; energy homeostasis [GO:0097009]; lung development [GO:0030324]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of autophagy [GO:0010507]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; neuron differentiation [GO:0030182]; positive regulation of cell death [GO:0010942]; positive regulation of cell growth [GO:0030307]; positive regulation of eukaryotic translation initiation factor 4F complex assembly [GO:1905537]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of mRNA cap binding [GO:1905612]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of translation in response to endoplasmic reticulum stress [GO:0036493]; regulation of polysome binding [GO:1905696]; regulation of presynapse assembly [GO:1905606]; regulation of translational initiation [GO:0006446]; response to ethanol [GO:0045471]; translation [GO:0006412]; translational initiation [GO:0006413] GO:0001662; GO:0003729; GO:0003743; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0005844; GO:0006412; GO:0006413; GO:0006446; GO:0008135; GO:0008190; GO:0010494; GO:0010507; GO:0010801; GO:0010942; GO:0016281; GO:0030182; GO:0030307; GO:0030324; GO:0031669; GO:0033138; GO:0034645; GO:0035278; GO:0036493; GO:0042802; GO:0045471; GO:0045666; GO:0051247; GO:0097009; GO:0098794; GO:1900087; GO:1905537; GO:1905606; GO:1905612; GO:1905696 31217 XM_029339268.2 98 10 8 10 25 Q9N2B7 4.41e-39 5-hydroxytryptamine receptor 1B (5-HT-1B) (5-HT1B) (Serotonin receptor 1B) Gorilla gorilla gorilla (Western lowland gorilla) adenylate cyclase-inhibiting serotonin receptor signaling pathway [GO:0007198]; behavior [GO:0007610]; bone remodeling [GO:0046849]; cellular response to alkaloid [GO:0071312]; cellular response to xenobiotic stimulus [GO:0071466]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; negative regulation of serotonin secretion [GO:0014063]; regulation of behavior [GO:0050795]; vasoconstriction [GO:0042310] GO:0004993; GO:0005886; GO:0007187; GO:0007198; GO:0007268; GO:0007610; GO:0014063; GO:0030425; GO:0030594; GO:0042310; GO:0045202; GO:0046849; GO:0050795; GO:0051378; GO:0071312; GO:0071466 31218 XM_029338058.2 0 7 0 0 9 NA NA NA NA NA NA 31219 XR_006393096.1 0 2 1 1 6 NA NA NA NA NA NA 31220 XR_006393587.1 35 62 32 39 19 NA NA NA NA NA NA 31221 XR_006394964.1 0 10 0 9 5 NA NA NA NA NA NA 31222 XM_044307844.1 123 123 0 133 114 NA NA NA NA NA NA 31223 XM_029345243.2 8 19 6 4 38 NA NA NA NA NA NA 31224 XM_029330493.2 348 766 710 976 266 NA NA NA NA NA NA 31225 XM_029331258.2 413 419 130 275 278 Q5E9H9 5.65e-73 Palmitoyl-protein thioesterase ABHD10, mitochondrial (EC 3.1.2.22) (Acyl-protein thioesterase ABHD10) (Alpha/beta hydrolase domain-containing protein 10) (Abhydrolase domain-containing protein 10) (Mycophenolic acid acyl-glucuronide esterase, mitochondrial) (EC 3.1.1.93) Bos taurus (Bovine) glucuronoside catabolic process [GO:0019391]; protein depalmitoylation [GO:0002084] GO:0002084; GO:0004553; GO:0005739; GO:0005829; GO:0008474; GO:0019391; GO:0102390 31226 XR_006396558.1 103 78 87 252 269 Q91287 5.77e-70 Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (PFR3) Pleurodeles waltl (Iberian ribbed newt) apoptotic process [GO:0006915]; positive regulation of cell population proliferation [GO:0008284] GO:0005007; GO:0005524; GO:0005886; GO:0006915; GO:0008284 31227 XR_006396558.1 103 78 87 252 269 Q91287 5.77e-70 Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (PFR3) Pleurodeles waltl (Iberian ribbed newt) apoptotic process [GO:0006915]; positive regulation of cell population proliferation [GO:0008284] GO:0005007; GO:0005524; GO:0005886; GO:0006915; GO:0008284 31228 XM_044326542.1 22 31 16 25 18 Q9UHC3 7.3e-52 Acid-sensing ion channel 3 (ASIC3) (hASIC3) (Amiloride-sensitive cation channel 3) (Neuronal amiloride-sensitive cation channel 3) (Testis sodium channel 1) (hTNaC1) Homo sapiens (Human) detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; sensory perception [GO:0007600]; sensory perception of sour taste [GO:0050915]; signal transduction [GO:0007165]; sodium ion transmembrane transport [GO:0035725] GO:0005261; GO:0005272; GO:0005886; GO:0007165; GO:0007600; GO:0009408; GO:0010447; GO:0015280; GO:0035725; GO:0042931; GO:0044736; GO:0048471; GO:0050915; GO:0050965; GO:0050966; GO:0050968 31229 XR_006395735.1 458 233 104 124 0 Q2T9I5 1.34e-21 RNA-binding protein 26 (RNA-binding motif protein 26) Xenopus laevis (African clawed frog) mRNA processing [GO:0006397] GO:0003723; GO:0005634; GO:0006397; GO:0046872 31230 XR_006395173.1 96 32 51 82 102 NA NA NA NA NA NA 31231 XM_044316740.1 42 28 12 43 54 NA NA NA NA NA NA 31232 XM_044326605.1 0 39 0 0 26 NA NA NA NA NA NA 31233 XM_029353792.2 63 40 115 26 91 NA NA NA NA NA NA 31234 XR_006391956.1 2 5 0 0 143 NA NA NA NA NA NA 31235 XM_029338083.2 796 291 227 416 706 Q2HJF7 0 Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta) (CaMK-II subunit delta) (EC 2.7.11.17) Bos taurus (Bovine) positive regulation of cardiac muscle hypertrophy [GO:0010613]; protein phosphorylation [GO:0006468]; regulation of cellular localization [GO:0060341] GO:0004683; GO:0005516; GO:0005524; GO:0005737; GO:0006468; GO:0010613; GO:0033017; GO:0042383; GO:0043005; GO:0060341; GO:0106310 31236 XM_029331368.2 0 0 42 0 0 NA NA NA NA NA NA 31237 XM_029342058.2 467 606 461 523 415 Q7YRH6 1.95e-57 Phosphatidylethanolamine N-methyltransferase (PEAMT) (PEMT) (EC 2.1.1.17) (EC 2.1.1.71) (Phospholipid methyltransferase) (PLMT) Bos taurus (Bovine) methylation [GO:0032259]; phosphatidylcholine biosynthetic process [GO:0006656] GO:0000773; GO:0004608; GO:0005789; GO:0006656; GO:0031966; GO:0032259; GO:0080101 31238 XM_044317244.1 334 44 27 93 67 NA NA NA NA NA NA 31239 XR_006396963.1 5 9 0 0 0 NA NA NA NA NA NA 31240 XM_044320584.1 320 0 0 0 0 NA NA NA NA NA NA 31241 XM_029345670.2 91 67 61 67 47 Q99999 7.74e-59 Galactosylceramide sulfotransferase (GalCer sulfotransferase) (EC 2.8.2.11) (3'-phosphoadenosine-5'-phosphosulfate:GalCer sulfotransferase) (3'-phosphoadenylylsulfate:galactosylceramide 3'-sulfotransferase) (Cerebroside sulfotransferase) Homo sapiens (Human) galactosylceramide biosynthetic process [GO:0006682]; galactosylceramide metabolic process [GO:0006681]; glycerolipid metabolic process [GO:0046486]; myelination [GO:0042552]; protein N-linked glycosylation [GO:0006487]; spermatogenesis [GO:0007283]; sphingolipid metabolic process [GO:0006665] GO:0000139; GO:0001733; GO:0005886; GO:0006487; GO:0006665; GO:0006681; GO:0006682; GO:0007283; GO:0008146; GO:0016020; GO:0042552; GO:0046486; GO:0050694 31242 XM_044319881.1 477 656 1772 2217 1351 Q6NXR0 3.36e-46 Interferon-inducible GTPase 5 (EC 3.6.5.-) (Immunity-related GTPase cinema 1) Homo sapiens (Human) cellular response to interferon-beta [GO:0035458]; defense response [GO:0006952] GO:0003924; GO:0005525; GO:0005789; GO:0006952; GO:0035458 31243 XM_029344212.2 1507 1141 868 1592 1700 Q5VTL8 1.54e-93 Pre-mRNA-splicing factor 38B (Sarcoma antigen NY-SAR-27) Homo sapiens (Human) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0003723; GO:0006397; GO:0008380; GO:0071011 31244 XR_006395900.1 2 3 32 23 23 NA NA NA NA NA NA 31245 XM_029345556.2 5 7 25 46 151 P26591 4.12e-93 Glutamate receptor Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004970; GO:0045211 31246 XM_029328486.2 1820 1251 1038 1715 1882 Q99460 0 26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit RPN2) (26S proteasome regulatory subunit S1) (26S proteasome subunit p112) Homo sapiens (Human) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of protein catabolic process [GO:0042176] GO:0000502; GO:0005576; GO:0005634; GO:0005654; GO:0005829; GO:0005838; GO:0008540; GO:0016020; GO:0022624; GO:0030234; GO:0031625; GO:0034515; GO:0035578; GO:0042176; GO:0043161 31247 XM_029336427.2 902 829 494 1075 775 Q7TN88 1.73e-84 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 31248 XM_029336427.2 902 829 494 1075 775 Q7TN88 2.08e-68 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 31249 XM_029343012.2 199 82 149 483 280 E7FAM5 3.55e-94 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 31250 XM_044320471.1 534 87 342 142 25 NA NA NA NA NA NA 31251 XR_003828422.2 47 57 24 83 156 NA NA NA NA NA NA 31252 XM_044321374.1 26 0 0 0 53 NA NA NA NA NA NA 31253 XM_029354156.2 1 0 21 1 48 Q9M2U3 8.78e-32 Protein ALP1-like (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) NA GO:0000118; GO:0004518; GO:0046872 31254 XM_029353181.2 12 0 13 0 52 NA NA NA NA NA NA 31255 XM_029332404.2 2191 2299 1703 2137 1251 NA NA NA NA NA NA 31256 XM_044307266.1 20 7 37 39 7 NA NA NA NA NA NA 31257 XR_006393258.1 5 0 0 0 17 NA NA NA NA NA NA 31258 XM_029340373.2 16 0 13 7 0 Q9R1C8 9.83e-23 5-hydroxytryptamine receptor 6 (5-HT-6) (5-HT6) (Serotonin receptor 6) Mus musculus (Mouse) cerebral cortex cell migration [GO:0021795]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; learning [GO:0007612]; long-term synaptic potentiation [GO:0060291]; negative regulation of acetylcholine secretion, neurotransmission [GO:0014058]; negative regulation of gamma-aminobutyric acid secretion [GO:0014053]; negative regulation of glutamate secretion [GO:0014050]; positive regulation of dopamine secretion [GO:0033603]; positive regulation of gamma-aminobutyric acid secretion [GO:0014054]; positive regulation of TOR signaling [GO:0032008] GO:0004993; GO:0005886; GO:0005929; GO:0007187; GO:0007268; GO:0007612; GO:0014050; GO:0014053; GO:0014054; GO:0014058; GO:0021795; GO:0030425; GO:0030594; GO:0032008; GO:0033603; GO:0045202; GO:0060291 31259 XM_044320794.1 28 3 21 16 20 P42688 2.19e-32 Tyrosine-protein kinase SRK2 (EC 2.7.10.2) Spongilla lacustris (Freshwater sponge) NA GO:0004715; GO:0005524; GO:0005737 31260 XM_044323077.1 49 26 40 57 38 NA NA NA NA NA NA 31261 XM_044308511.1 855 229 218 737 40 NA NA NA NA NA NA 31262 XM_044323853.1 0 18 9 81 0 NA NA NA NA NA NA 31263 XM_029323858.2 274 64 0 272 170 Q01133 6.5e-30 Antho-RFamide neuropeptides [Cleaved into: Antho-RFamide] Calliactis parasitica (Sea anemone) (Actinia parasitica) neuropeptide signaling pathway [GO:0007218] GO:0005576; GO:0007218 31264 XM_029323858.2 274 64 0 272 170 Q01133 2.58e-27 Antho-RFamide neuropeptides [Cleaved into: Antho-RFamide] Calliactis parasitica (Sea anemone) (Actinia parasitica) neuropeptide signaling pathway [GO:0007218] GO:0005576; GO:0007218 31265 XM_029352130.2 11607 14111 5897 13545 10528 NA NA NA NA NA NA 31266 XM_029347002.2 1020 387 308 56 255 NA NA NA NA NA NA 31267 XM_029344816.2 10 3 8 9 13 NA NA NA NA NA NA 31268 XM_029325713.2 190 89 148 199 302 Q9NRL2 1.3e-21 Bromodomain adjacent to zinc finger domain protein 1A (ATP-dependent chromatin-remodeling protein) (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (CHRAC subunit ACF1) (Williams syndrome transcription factor-related chromatin-remodeling factor 180) (WCRF180) (hWALp1) Homo sapiens (Human) chromatin remodeling [GO:0006338]; DNA-templated DNA replication [GO:0006261]; nucleosome assembly [GO:0006334]; positive regulation of DNA replication [GO:0045740]; regulation of DNA replication [GO:0006275]; regulation of DNA-templated transcription [GO:0006355]; regulation of heterochromatin formation [GO:0031445]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000228; GO:0003677; GO:0005634; GO:0005721; GO:0006261; GO:0006275; GO:0006334; GO:0006338; GO:0006355; GO:0006357; GO:0008623; GO:0016590; GO:0031445; GO:0045740; GO:0046872 31269 XR_003823898.2 345 284 211 174 739 NA NA NA NA NA NA 31270 XM_044311904.1 19 8 12 22 72 NA NA NA NA NA NA 31271 XR_006394147.1 0 15 0 34 0 NA NA NA NA NA NA 31272 XM_044312013.1 7 0 10 0 4 NA NA NA NA NA NA 31273 XM_044319829.1 50 15 16 50 55 O74212 1.77e-135 Acyl-lipid (8-3)-desaturase (EC 1.14.19.30) (Delta(5) fatty acid desaturase) (Delta-5 fatty acid desaturase) Mortierella alpina (Oleaginous fungus) (Mortierella renispora) fatty acid biosynthetic process [GO:0006633] GO:0006633; GO:0016020; GO:0020037; GO:0046872; GO:0102866 31274 XM_029350149.2 1940 2332 440 2399 3990 Q9UHB7 3.11e-47 AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31 protein) (Protein AF-5q31) (Major CDK9 elongation factor-associated protein) Homo sapiens (Human) regulation of gene expression [GO:0010468]; spermatid development [GO:0007286] GO:0000791; GO:0001650; GO:0005654; GO:0007286; GO:0008023; GO:0010468; GO:0032783 31275 XM_044327543.1 0 0 0 333 0 P10894 0 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (EC 3.1.4.11) (PLC-154) (Phosphoinositide phospholipase C-beta-1) (Phospholipase C-beta-1) (PLC-beta-1) Bos taurus (Bovine) interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-15-mediated signaling pathway [GO:0035723]; lipid catabolic process [GO:0016042]; memory [GO:0007613]; phosphatidylinositol metabolic process [GO:0046488]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of JNK cascade [GO:0046330] GO:0004435; GO:0005096; GO:0005509; GO:0005516; GO:0005546; GO:0005737; GO:0005829; GO:0007613; GO:0016042; GO:0016607; GO:0019899; GO:0031965; GO:0035722; GO:0035723; GO:0046330; GO:0046488; GO:0048015; GO:0070498 31276 XR_006395110.1 2026 1440 614 838 1442 NA NA NA NA NA NA 31277 XM_029344648.2 2976 893 1171 1096 1327 Q99L04 9.01e-101 Dehydrogenase/reductase SDR family member 1 (EC 1.1.1.-) (Short chain dehydrogenase/reductase family 19C member 1) (Protein SDR19C1) Mus musculus (Mouse) NA GO:0004090; GO:0005739; GO:0005743; GO:0005783; GO:0016616; GO:0047045 31278 XM_029335172.2 324 363 176 246 273 Q5HZH2 1.18e-80 18S rRNA aminocarboxypropyltransferase (EC 2.5.1.-) (20S S rRNA accumulation protein 3 homolog) Mus musculus (Mouse) enzyme-directed rRNA pseudouridine synthesis [GO:0000455]; maturation of SSU-rRNA [GO:0030490] GO:0000455; GO:0005737; GO:0016740; GO:0030490; GO:0106388; GO:1904047 31279 XM_029350537.2 151 11 35 0 124 NA NA NA NA NA NA 31280 XM_029353707.2 54 0 43 0 16 P35406 1.3e-36 D(1) dopamine receptor (Dopamine D1 receptor) Carassius auratus (Goldfish) regulation of biological quality [GO:0065008] GO:0004930; GO:0005886; GO:0065008 31281 XM_044329166.1 3114 2101 1492 2737 2517 A6QLE6 1.67e-179 Anoctamin-4 (Transmembrane protein 16D) Bos taurus (Bovine) chloride transmembrane transport [GO:1902476]; lipid transport [GO:0006869]; transmembrane transport [GO:0055085] GO:0005229; GO:0005254; GO:0005886; GO:0006869; GO:0046983; GO:0055085; GO:1902476 31282 XM_029337553.2 2257 1734 1434 2216 2637 Q8VE97 2.97e-45 Serine/arginine-rich splicing factor 4 (Splicing factor, arginine/serine-rich 4) Mus musculus (Mouse) hematopoietic progenitor cell differentiation [GO:0002244]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025] GO:0000398; GO:0002244; GO:0003723; GO:0003729; GO:0005634; GO:0016607; GO:0048025; GO:1990825 31283 XM_044308261.1 0 208 25 289 121 NA NA NA NA NA NA 31284 XM_029344885.2 180 155 91 85 54 NA NA NA NA NA NA 31285 XM_029330712.2 1100 585 284 1210 853 A1L3F5 1.64e-103 C-Maf-inducing protein (c-Mip) Xenopus laevis (African clawed frog) NA GO:0005634; GO:0005737 31286 XM_029330712.2 1100 585 284 1210 853 A1L3F5 2.58e-87 C-Maf-inducing protein (c-Mip) Xenopus laevis (African clawed frog) NA GO:0005634; GO:0005737 31287 XM_044319314.1 869 679 287 562 507 NA NA NA NA NA NA 31288 XM_029336185.2 1803 1824 1573 2153 2449 A5D7E2 0 Transmembrane 9 superfamily member 4 Bos taurus (Bovine) cell adhesion [GO:0007155]; phagocytosis [GO:0006909]; positive regulation of protein exit from endoplasmic reticulum [GO:0070863]; positive regulation of protein localization to cell surface [GO:2000010]; protein localization to membrane [GO:0072657]; regulation of intracellular pH [GO:0051453]; response to hypoxia [GO:0001666]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072] GO:0001666; GO:0005769; GO:0005794; GO:0006909; GO:0007155; GO:0016020; GO:0051453; GO:0070072; GO:0070863; GO:0072657; GO:2000010 31289 XM_029358129.2 46 312 90 162 111 NA NA NA NA NA NA 31290 XM_044315323.1 0 10 0 3 22 NA NA NA NA NA NA 31291 XM_029345445.2 0 14 23 0 0 NA NA NA NA NA NA 31292 XM_029344463.2 0 72 184 0 0 Q8K078 3.57e-102 Solute carrier organic anion transporter family member 4A1 (Organic anion-transporting polypeptide E) (OATP-E) (Sodium-independent organic anion transporter E) (Solute carrier family 21 member 12) Mus musculus (Mouse) sodium-independent organic anion transport [GO:0043252]; thyroid hormone metabolic process [GO:0042403] GO:0005886; GO:0008514; GO:0015132; GO:0015347; GO:0015349; GO:0042403; GO:0043252 31293 XM_044307267.1 38 3 11 21 132 NA NA NA NA NA NA 31294 XM_029346381.2 78 50 37 55 44 NA NA NA NA NA NA 31295 XR_006397148.1 25 30 0 13 1 NA NA NA NA NA NA 31296 XM_044311781.1 0 7 2 0 4 NA NA NA NA NA NA 31297 XM_029352344.2 1 0 6 0 12 NA NA NA NA NA NA 31298 XR_006398123.1 1052 1166 425 678 448 NA NA NA NA NA NA 31299 XM_044325872.1 0 0 6 0 0 NA NA NA NA NA NA 31300 XM_029344365.2 14576 13544 8075 10585 13155 Q5XJ85 5.19e-27 Myeloid differentiation primary response protein MyD88 Danio rerio (Zebrafish) (Brachydanio rerio) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; monocyte activation [GO:0042117]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; neutrophil activation involved in immune response [GO:0002283]; neutrophil chemotaxis [GO:0030593]; positive regulation of hematopoietic progenitor cell differentiation [GO:1901534]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of hematopoietic progenitor cell differentiation [GO:1901532]; response to molecule of bacterial origin [GO:0002237]; Toll signaling pathway [GO:0008063] GO:0002218; GO:0002237; GO:0002283; GO:0002755; GO:0005737; GO:0005886; GO:0006954; GO:0008063; GO:0030593; GO:0035325; GO:0042117; GO:0042742; GO:0043123; GO:0045087; GO:0050830; GO:0070976; GO:1901532; GO:1901534 31301 XM_044327130.1 76 123 0 175 2 NA NA NA NA NA NA 31302 XM_044311647.1 128 245 29 684 157 Q90610 5.37e-32 Neogenin Gallus gallus (Chicken) cell adhesion [GO:0007155] GO:0005886; GO:0007155 31303 XM_044320752.1 12 0 0 5 8 NA NA NA NA NA NA 31304 XM_029349708.2 20 4 1 5 14 B8VIU6 2.81e-74 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 31305 XM_029336991.2 1206 2848 1731 4642 3245 NA NA NA NA NA NA 31306 XR_006397422.1 0 0 6 0 0 NA NA NA NA NA NA 31307 XM_044307528.1 7 0 0 0 0 NA NA NA NA NA NA 31308 XM_029333698.2 2991 3603 1668 2421 2886 Q9H0Y0 9.38e-35 Ubiquitin-like-conjugating enzyme ATG10 (EC 2.3.2.-) (Autophagy-related protein 10) (APG10-like) Homo sapiens (Human) autophagy [GO:0006914]; ER overload response [GO:0006983]; macroautophagy [GO:0016236]; positive regulation of protein modification process [GO:0031401]; protein lipidation [GO:0006497]; protein modification by small protein conjugation [GO:0032446]; protein transport [GO:0015031] GO:0005829; GO:0006497; GO:0006914; GO:0006983; GO:0015031; GO:0016236; GO:0019777; GO:0031401; GO:0032446 31309 XM_044318048.1 0 14 0 0 0 NA NA NA NA NA NA 31310 XM_029336088.2 8369 8956 6515 7363 5498 Q5R9Z1 1.27e-111 Vacuolar protein sorting-associated protein 29 (Vesicle protein sorting 29) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) endocytic recycling [GO:0032456]; protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147] GO:0005769; GO:0005770; GO:0005829; GO:0010008; GO:0015031; GO:0030904; GO:0032456; GO:0042147; GO:0046872 31311 XM_044320286.1 110 56 81 161 83 NA NA NA NA NA NA 31312 XM_044323913.1 172 4 8 50 24 P27590 2.12e-45 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Rattus norvegicus (Rat) antibacterial innate immune response [GO:0140367]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; autophagy [GO:0006914]; calcium ion homeostasis [GO:0055074]; cellular calcium ion homeostasis [GO:0006874]; cellular chloride ion homeostasis [GO:0030644]; cellular phosphate ion homeostasis [GO:0030643]; cellular response to unfolded protein [GO:0034620]; cellular sodium ion homeostasis [GO:0006883]; chaperone-mediated protein folding [GO:0061077]; chemical homeostasis [GO:0048878]; chloride ion homeostasis [GO:0055064]; citric acid secretion [GO:0046720]; collecting duct development [GO:0072044]; connective tissue replacement [GO:0097709]; creatinine homeostasis [GO:0097273]; defense response to Gram-negative bacterium [GO:0050829]; endoplasmic reticulum organization [GO:0007029]; gene expression [GO:0010467]; glomerular filtration [GO:0003094]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; ion homeostasis [GO:0050801]; juxtaglomerular apparatus development [GO:0072051]; kidney development [GO:0001822]; leukocyte cell-cell adhesion [GO:0007159]; lipid metabolic process [GO:0006629]; loop of Henle development [GO:0072070]; metanephric ascending thin limb development [GO:0072218]; metanephric distal convoluted tubule development [GO:0072221]; metanephric thick ascending limb development [GO:0072233]; micturition [GO:0060073]; multicellular organismal homeostasis [GO:0048871]; multicellular organismal response to stress [GO:0033555]; neutrophil migration [GO:1990266]; organ or tissue specific immune response [GO:0002251]; peptidyl-threonine phosphorylation [GO:0018107]; phosphate ion homeostasis [GO:0055062]; potassium ion homeostasis [GO:0055075]; protein localization to vacuole [GO:0072665]; protein phosphorylation [GO:0006468]; protein transport into plasma membrane raft [GO:0044861]; regulation of blood pressure [GO:0008217]; regulation of protein transport [GO:0051223]; regulation of urine volume [GO:0035809]; renal sodium ion absorption [GO:0070294]; renal urate salt excretion [GO:0097744]; renal water homeostasis [GO:0003091]; response to endoplasmic reticulum stress [GO:0034976]; response to lipopolysaccharide [GO:0032496]; response to organic substance [GO:0010033]; response to unfolded protein [GO:0006986]; response to water deprivation [GO:0009414]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; sodium ion homeostasis [GO:0055078]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; ubiquitin-dependent ERAD pathway [GO:0030433]; urate transport [GO:0015747]; urea transmembrane transport [GO:0071918]; water homeostasis [GO:0030104] GO:0000922; GO:0001822; GO:0002251; GO:0003091; GO:0003094; GO:0005201; GO:0005509; GO:0005615; GO:0005783; GO:0005794; GO:0005886; GO:0005929; GO:0006468; GO:0006629; GO:0006874; GO:0006883; GO:0006914; GO:0006915; GO:0006954; GO:0006986; GO:0007029; GO:0007157; GO:0007159; GO:0008217; GO:0008380; GO:0009410; GO:0009414; GO:0009986; GO:0010033; GO:0010467; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0018107; GO:0019864; GO:0030104; GO:0030433; GO:0030643; GO:0030644; GO:0031410; GO:0032496; GO:0033209; GO:0033555; GO:0034620; GO:0034976; GO:0035809; GO:0044861; GO:0045121; GO:0045177; GO:0046720; GO:0048871; GO:0048878; GO:0050801; GO:0050829; GO:0051223; GO:0055062; GO:0055064; GO:0055074; GO:0055075; GO:0055078; GO:0060073; GO:0060170; GO:0061077; GO:0070294; GO:0071918; GO:0072044; GO:0072051; GO:0072070; GO:0072218; GO:0072221; GO:0072233; GO:0072665; GO:0097190; GO:0097273; GO:0097709; GO:0097744; GO:0140367; GO:1990266 31313 XM_044312042.1 7 38 0 0 0 NA NA NA NA NA NA 31314 XM_029324373.2 375 290 139 163 363 Q7SYK1 0 Queuine tRNA-ribosyltransferase catalytic subunit 1 (EC 2.4.2.64) (Guanine insertion enzyme) (tRNA-guanine transglycosylase) Danio rerio (Zebrafish) (Brachydanio rerio) tRNA-guanine transglycosylation [GO:0101030] GO:0005741; GO:0008479; GO:0042803; GO:0046872; GO:0046982; GO:0101030 31315 XM_029334765.2 3178 2376 2511 2721 1920 Q12996 0 Cleavage stimulation factor subunit 3 (CF-1 77 kDa subunit) (Cleavage stimulation factor 77 kDa subunit) (CSTF 77 kDa subunit) (CstF-77) Homo sapiens (Human) mRNA cleavage [GO:0006379]; mRNA polyadenylation [GO:0006378]; RNA 3'-end processing [GO:0031123] GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0006378; GO:0006379; GO:0031123 31316 XM_044310043.1 153 25 0 267 299 Q28824 8.75e-75 Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form] Bos taurus (Bovine) protein phosphorylation [GO:0006468]; tonic smooth muscle contraction [GO:0014820] GO:0001725; GO:0003779; GO:0004672; GO:0004687; GO:0005516; GO:0005524; GO:0005737; GO:0006468; GO:0014820; GO:0030027; GO:0032154; GO:0046872 31317 XM_029358302.2 0 0 0 0 701 Q9QYS2 0 Metabotropic glutamate receptor 3 (mGluR3) Mus musculus (Mouse) G protein-coupled glutamate receptor signaling pathway [GO:0007216]; gene expression [GO:0010467]; modulation of chemical synaptic transmission [GO:0050804]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; regulation of sensory perception of pain [GO:0051930]; regulation of synaptic transmission, glutamatergic [GO:0051966]; sensory perception of pain [GO:0019233]; synaptic transmission, glutamatergic [GO:0035249] GO:0001640; GO:0001641; GO:0005246; GO:0005886; GO:0007216; GO:0010467; GO:0014069; GO:0019233; GO:0030424; GO:0035249; GO:0042734; GO:0043005; GO:0043197; GO:0045211; GO:0048786; GO:0050804; GO:0051930; GO:0051966; GO:0097110; GO:0097449; GO:0098978; GO:0099170 31318 XM_044327825.1 0 112 0 11 2 NA NA NA NA NA NA 31319 XM_044323379.1 7 9 8 30 5 Q9LHQ6 6.52e-61 Organic cation/carnitine transporter 4 (AtOCT4) Arabidopsis thaliana (Mouse-ear cress) cellular response to water deprivation [GO:0042631]; ion transport [GO:0006811] GO:0005524; GO:0006811; GO:0009535; GO:0009705; GO:0022857; GO:0042631 31320 XR_006397317.1 0 0 0 1 19 NA NA NA NA NA NA 31321 XR_006396271.1 525 410 155 189 124 NA NA NA NA NA NA 31322 XM_044311467.1 62 0 0 20 13 NA NA NA NA NA NA 31323 XM_029323686.2 1298 1131 319 1252 779 Q9QXT1 1.07e-78 Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide (mDAPP1) (B lymphocyte adapter protein Bam32) (B-cell adapter molecule of 32 kDa) Mus musculus (Mouse) NA GO:0005547; GO:0005737; GO:0005886; GO:0043325 31324 XM_044326684.1 1445 1078 727 1306 1370 Q05B79 0 ATP-dependent DNA/RNA helicase DHX36 (EC 3.6.4.12) (EC 3.6.4.13) (DEAD/H box polypeptide 36) (DEAH-box protein 36) (G4-resolvase-1) (G4R1) (MLE-like protein 1) (RNA helicase associated with AU-rich element protein) Bos taurus (Bovine) 3'-UTR-mediated mRNA destabilization [GO:0061158]; cell differentiation [GO:0030154]; cellular response to arsenite ion [GO:1903843]; cellular response to heat [GO:0034605]; cellular response to UV [GO:0034644]; defense response to virus [GO:0051607]; G-quadruplex DNA unwinding [GO:0044806]; innate immune response [GO:0045087]; negative regulation of translation [GO:0017148]; ossification [GO:0001503]; positive regulation of cardioblast differentiation [GO:0051891]; positive regulation of cytoplasmic translation [GO:2000767]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of gene expression [GO:0010628]; positive regulation of hematopoietic progenitor cell differentiation [GO:1901534]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of intracellular mRNA localization [GO:1904582]; positive regulation of mRNA 3'-end processing [GO:0031442]; positive regulation of myeloid dendritic cell cytokine production [GO:0002735]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of telomere maintenance via telomere lengthening [GO:1904358]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; regulation of embryonic development [GO:0045995]; regulation of mRNA stability [GO:0043488]; regulation of transcription by RNA polymerase III [GO:0006359]; response to exogenous dsRNA [GO:0043330]; RNA secondary structure unwinding [GO:0010501]; spermatogenesis [GO:0007283]; telomerase RNA stabilization [GO:0090669] GO:0000287; GO:0000781; GO:0000978; GO:0001503; GO:0002151; GO:0002735; GO:0003678; GO:0003697; GO:0003723; GO:0003724; GO:0003725; GO:0003730; GO:0005524; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0006359; GO:0007283; GO:0010494; GO:0010501; GO:0010628; GO:0016607; GO:0016887; GO:0017148; GO:0030154; GO:0030424; GO:0030425; GO:0031442; GO:0032727; GO:0034605; GO:0034644; GO:0035925; GO:0042826; GO:0043123; GO:0043204; GO:0043330; GO:0043488; GO:0044806; GO:0045087; GO:0045944; GO:0045995; GO:0048027; GO:0051607; GO:0051880; GO:0051891; GO:0060261; GO:0061003; GO:0061158; GO:0070034; GO:0070883; GO:0090669; GO:1900153; GO:1901534; GO:1903843; GO:1904358; GO:1904582; GO:2000767 31325 XM_029347063.2 1 5 9 0 31 P42893 6.09e-103 Endothelin-converting enzyme 1 (ECE-1) (EC 3.4.24.71) Rattus norvegicus (Rat) apoptotic process [GO:0006915]; axonogenesis involved in innervation [GO:0060385]; blood vessel diameter maintenance [GO:0097746]; bradykinin catabolic process [GO:0010815]; calcitonin catabolic process [GO:0010816]; ear development [GO:0043583]; embryonic digit morphogenesis [GO:0042733]; embryonic heart tube development [GO:0035050]; endothelin maturation [GO:0034959]; gene expression [GO:0010467]; heart development [GO:0007507]; hormone catabolic process [GO:0042447]; neuron projection development [GO:0031175]; peptide hormone processing [GO:0016486]; pharyngeal system development [GO:0060037]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of receptor recycling [GO:0001921]; protein processing [GO:0016485]; regulation of blood pressure [GO:0008217]; regulation of ERK1 and ERK2 cascade [GO:0070372]; response to cadmium ion [GO:0046686]; response to hypoxia [GO:0001666]; response to muscle stretch [GO:0035994]; response to xenobiotic stimulus [GO:0009410]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; substance P catabolic process [GO:0010814]; sympathetic neuron axon guidance [GO:0097492] GO:0001666; GO:0001921; GO:0004175; GO:0004222; GO:0005768; GO:0005769; GO:0005886; GO:0006915; GO:0007507; GO:0008217; GO:0008270; GO:0009410; GO:0009897; GO:0010467; GO:0010613; GO:0010814; GO:0010815; GO:0010816; GO:0016020; GO:0016485; GO:0016486; GO:0030141; GO:0031175; GO:0031410; GO:0031982; GO:0033093; GO:0034959; GO:0035050; GO:0035994; GO:0042447; GO:0042733; GO:0042802; GO:0042803; GO:0043583; GO:0043950; GO:0045745; GO:0046686; GO:0048471; GO:0060037; GO:0060385; GO:0070372; GO:0097492; GO:0097746; GO:1902287 31326 XM_044319024.1 196 127 114 154 151 Q9UHC6 1.5e-33 Contactin-associated protein-like 2 (Cell recognition molecule Caspr2) Homo sapiens (Human) adult behavior [GO:0030534]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell population proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; clustering of voltage-gated potassium channels [GO:0045163]; learning [GO:0007612]; limbic system development [GO:0021761]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuron recognition [GO:0008038]; positive regulation of gap junction assembly [GO:1903598]; protein localization to juxtaparanode region of axon [GO:0071205]; social behavior [GO:0035176]; striatum development [GO:0021756]; superior temporal gyrus development [GO:0071109]; thalamus development [GO:0021794]; transmission of nerve impulse [GO:0019226]; vocal learning [GO:0042297]; vocalization behavior [GO:0071625] GO:0005769; GO:0005794; GO:0007155; GO:0007420; GO:0007612; GO:0008038; GO:0008076; GO:0008283; GO:0009986; GO:0016020; GO:0019226; GO:0019899; GO:0021756; GO:0021761; GO:0021794; GO:0021987; GO:0030424; GO:0030425; GO:0030534; GO:0030673; GO:0031175; GO:0033010; GO:0035176; GO:0042297; GO:0043025; GO:0043204; GO:0044224; GO:0045163; GO:0048812; GO:0071109; GO:0071205; GO:0071625; GO:1903598 31327 XM_044310143.1 18 13 95 8 35 NA NA NA NA NA NA 31328 XR_006396582.1 0 0 0 6068 3 NA NA NA NA NA NA 31329 XM_029334738.2 749 805 753 1227 847 Q5M8E6 1.86e-140 tRNA N(3)-methylcytidine methyltransferase METTL2 (EC 2.1.1.-) (Methyltransferase-like protein 2) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) tRNA methylation [GO:0030488] GO:0005737; GO:0016427; GO:0030488 31330 XM_029324859.2 1019 835 374 684 768 Q6P3R8 3.88e-76 Serine/threonine-protein kinase Nek5 (EC 2.7.11.1) (Never in mitosis A-related kinase 5) (NimA-related protein kinase 5) Homo sapiens (Human) protein phosphorylation [GO:0006468] GO:0004672; GO:0004674; GO:0005524; GO:0006468; GO:0046872; GO:0106310 31331 XM_044308805.1 3 7 32 26 6 NA NA NA NA NA NA 31332 XM_029333434.2 684 1187 28 727 539 P55115 1.07e-47 Zinc metalloproteinase nas-15 (EC 3.4.24.-) (Nematode astacin 15) Caenorhabditis elegans proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0006508; GO:0008270 31333 XM_029328775.2 12 8 0 6 45 P51471 1.27e-26 Blue-sensitive opsin (Blue photoreceptor pigment) (RH2 opsin) Anolis carolinensis (Green anole) (American chameleon) absorption of visible light [GO:0016038]; cellular response to light stimulus [GO:0071482]; G protein-coupled receptor signaling pathway [GO:0007186]; light absorption [GO:0016037]; phototransduction [GO:0007602]; visual perception [GO:0007601] GO:0001750; GO:0005886; GO:0007186; GO:0007601; GO:0007602; GO:0008020; GO:0016037; GO:0016038; GO:0071482 31334 XM_029332043.2 22 9 6 0 7 NA NA NA NA NA NA 31335 XM_044315275.1 240 9 99 12 3 Q80W99 1.16e-59 Cation channel sperm-associated protein 3 (CatSper3) Mus musculus (Mouse) establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; regulation of ion transmembrane transport [GO:0034765]; sodium ion transport [GO:0006814]; sperm capacitation [GO:0048240] GO:0001669; GO:0005245; GO:0005783; GO:0006814; GO:0030317; GO:0031514; GO:0034765; GO:0036128; GO:0048240; GO:0051649 31336 XM_029358638.2 0 0 0 127 118 NA NA NA NA NA NA 31337 XR_006393523.1 84 0 131 64 51 NA NA NA NA NA NA 31338 XM_044326668.1 67 44 16 53 50 NA NA NA NA NA NA 31339 XM_044309231.1 29 0 9 7 45 NA NA NA NA NA NA 31340 XM_044312195.1 57 2 1 9 6 NA NA NA NA NA NA 31341 XM_029335631.2 881 917 455 711 878 Q9D7A8 4.81e-68 Armadillo repeat-containing protein 1 Mus musculus (Mouse) intracellular distribution of mitochondria [GO:0048312] GO:0005739; GO:0005741; GO:0005829; GO:0046872; GO:0048312 31342 XM_044317312.1 516 0 2 1 1 NA NA NA NA NA NA 31343 XM_044321975.1 448 63 187 206 224 Q0EEE2 5.05e-76 Patched domain-containing protein 3 (RND-type protein RNDEu-3) Mus musculus (Mouse) NA GO:0005783; GO:0005789; GO:0005886; GO:0016020; GO:0097225 31344 XM_029326591.2 0 0 29 82 0 P97288 3.96e-36 5-hydroxytryptamine receptor 4 (5-HT-4) (5-HT4) (Serotonin receptor 4) Mus musculus (Mouse) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting serotonin receptor signaling pathway [GO:0007198]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; gamma-aminobutyric acid signaling pathway [GO:0007214]; regulation of appetite [GO:0032098] GO:0004993; GO:0005737; GO:0005768; GO:0005886; GO:0007187; GO:0007189; GO:0007198; GO:0007214; GO:0007268; GO:0016020; GO:0030425; GO:0030594; GO:0032098; GO:0045202; GO:0051378 31345 XR_006396351.1 8 6 38 19 98 NA NA NA NA NA NA 31346 XM_044319847.1 32 7 15 19 38 P0CI65 1.07e-52 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 31347 XM_044319847.1 32 7 15 19 38 P0CI65 3.32e-50 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 31348 XM_044319847.1 32 7 15 19 38 P0CI65 1.02e-42 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 31349 XM_044319847.1 32 7 15 19 38 P0CI65 3.4e-29 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 31350 XM_029335650.2 480 130 189 484 308 Q8N8A2 4.22e-77 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (PP6-ARS-B) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-B) (Ankyrin repeat domain-containing protein 44) Homo sapiens (Human) NA NA 31351 XM_029335650.2 480 130 189 484 308 Q8N8A2 3.56e-74 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (PP6-ARS-B) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-B) (Ankyrin repeat domain-containing protein 44) Homo sapiens (Human) NA NA 31352 XM_029335650.2 480 130 189 484 308 Q8N8A2 4.48e-68 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (PP6-ARS-B) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-B) (Ankyrin repeat domain-containing protein 44) Homo sapiens (Human) NA NA 31353 XM_029335650.2 480 130 189 484 308 Q8N8A2 8.95e-45 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (PP6-ARS-B) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-B) (Ankyrin repeat domain-containing protein 44) Homo sapiens (Human) NA NA 31354 XM_044320319.1 38 246 58 156 0 Q14CM0 6.87e-91 FERM and PDZ domain-containing protein 4 (PDZ domain-containing protein 10) (PSD-95-interacting regulator of spine morphogenesis) (Preso) Homo sapiens (Human) positive regulation of synapse structural plasticity [GO:0051835] GO:0005546; GO:0005856; GO:0032991; GO:0043197; GO:0051835 31355 XM_029332641.2 282 10 208 567 626 P49337 2.28e-67 Protein Wnt-4 Gallus gallus (Chicken) canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; kidney morphogenesis [GO:0060993]; negative regulation of androgen biosynthetic process [GO:2000180]; neuron differentiation [GO:0030182]; positive regulation of cartilage development [GO:0061036]; positive regulation of skeletal muscle cell proliferation [GO:0014858]; positive regulation of skeletal muscle fiber differentiation [GO:1902811] GO:0005109; GO:0005125; GO:0005615; GO:0005737; GO:0014858; GO:0030182; GO:0045165; GO:0060070; GO:0060993; GO:0061036; GO:1902811; GO:2000180 31356 XM_029357498.2 262 1 3 59 346 P23824 2.69e-70 GATA-binding factor 2 (GATA-2) (Transcription factor NF-E1b) Gallus gallus (Chicken) cell fate commitment [GO:0045165]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of angiogenesis [GO:0045766]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000122; GO:0000978; GO:0000981; GO:0001223; GO:0005634; GO:0008270; GO:0045165; GO:0045766; GO:0045944; GO:1902895 31357 XM_029348409.2 1075 772 231 209 510 NA NA NA NA NA NA 31358 XR_006391495.1 14 8 4 156 3 NA NA NA NA NA NA 31359 XM_044314497.1 10 4 24 0 41 B3EWZ5 4.4e-27 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 31360 XM_044314497.1 10 4 24 0 41 B3EWZ5 6.38e-26 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 31361 XM_044314497.1 10 4 24 0 41 B3EWZ5 9.62e-26 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 31362 XM_044314497.1 10 4 24 0 41 B3EWZ5 1.15e-24 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 31363 XM_044314497.1 10 4 24 0 41 B3EWZ5 2.58e-24 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 31364 XM_044314497.1 10 4 24 0 41 B3EWZ5 5.13e-24 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 31365 XM_044314497.1 10 4 24 0 41 B3EWZ5 7.66e-24 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 31366 XM_044314497.1 10 4 24 0 41 B3EWZ5 9.01e-24 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 31367 XM_044314497.1 10 4 24 0 41 B3EWZ5 2.23e-23 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 31368 XM_044314497.1 10 4 24 0 41 B3EWZ5 1.23e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 31369 XM_044314497.1 10 4 24 0 41 B3EWZ5 3.08e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 31370 XM_044327946.1 0 0 0 5 27 NA NA NA NA NA NA 31371 XM_044319648.1 7379 3708 6361 6338 5915 NA NA NA NA NA NA 31372 XR_006393377.1 0 0 0 0 32 NA NA NA NA NA NA 31373 XM_044316608.1 353 200 241 451 821 Q5RGU1 0 Atypical kinase COQ8A, mitochondrial (EC 2.7.-.-) (Chaperone activity of bc1 complex-like) (Chaperone-ABC1-like) (Coenzyme Q protein 8A) (aarF domain-containing protein kinase 3) Danio rerio (Zebrafish) (Brachydanio rerio) phosphorylation [GO:0016310]; ubiquinone biosynthetic process [GO:0006744] GO:0005524; GO:0005739; GO:0006744; GO:0016301; GO:0016310; GO:0031314; GO:0043531 31374 XR_006393863.1 2 0 6 0 15 NA NA NA NA NA NA 31375 XM_029345907.2 54 16 40 12 14 NA NA NA NA NA NA 31376 XM_044316536.1 0 0 0 0 39 Q8BP78 2.69e-76 Protein FRA10AC1 homolog Mus musculus (Mouse) dephosphorylation [GO:0016311] GO:0005634; GO:0016311; GO:0016791 31377 XM_044316528.1 123 203 78 144 265 Q8BS35 2.34e-155 Alkylglycerol monooxygenase (EC 1.14.16.5) (Transmembrane protein 195) Mus musculus (Mouse) ether lipid metabolic process [GO:0046485]; lipid biosynthetic process [GO:0008610]; membrane lipid metabolic process [GO:0006643] GO:0005506; GO:0005783; GO:0005789; GO:0006643; GO:0008610; GO:0046485; GO:0050479 31378 XM_044324749.1 0 0 0 0 88 Q9UKP5 8.75e-95 A disintegrin and metalloproteinase with thrombospondin motifs 6 (ADAM-TS 6) (ADAM-TS6) (ADAMTS-6) (EC 3.4.24.-) Homo sapiens (Human) aorta development [GO:0035904]; cardiac septum development [GO:0003279]; coronary vasculature development [GO:0060976]; extracellular matrix organization [GO:0030198]; kidney development [GO:0001822]; proteolysis [GO:0006508] GO:0001822; GO:0003279; GO:0004222; GO:0005576; GO:0006508; GO:0008237; GO:0030198; GO:0031012; GO:0035904; GO:0046872; GO:0060976 31379 XM_029334677.2 850 708 502 729 653 A0A5G2QD80 5.87e-62 Dynactin subunit 2 Sus scrofa (Pig) microtubule-based process [GO:0007017] GO:0005737; GO:0005869; GO:0007017; GO:0030286 31380 XM_029355634.2 80 68 86 192 47 NA NA NA NA NA NA 31381 XM_044320395.1 272 0 0 0 0 NA NA NA NA NA NA 31382 XM_029324886.2 123 92 21 87 28 NA NA NA NA NA NA 31383 XM_044328341.1 12 0 0 4 6 Q58DM8 2.12e-122 Enoyl-CoA hydratase, mitochondrial (mECH) (mECH1) (EC 4.2.1.17) (EC 5.3.3.8) (Enoyl-CoA hydratase 1) (ECHS1) (Short-chain enoyl-CoA hydratase) (SCEH) Bos taurus (Bovine) fatty acid beta-oxidation [GO:0006635] GO:0004165; GO:0004300; GO:0005739; GO:0005759; GO:0006635; GO:0043956; GO:0120092 31384 XM_029332718.2 43 49 51 63 39 Q9JME2 9.26e-40 Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4S-1) (C4ST-1) (C4ST1) Mus musculus (Mouse) apoptotic process [GO:0006915]; carbohydrate biosynthetic process [GO:0016051]; cartilage development [GO:0051216]; chondrocyte development [GO:0002063]; chondroitin sulfate biosynthetic process [GO:0030206]; chondroitin sulfate metabolic process [GO:0030204]; developmental growth [GO:0048589]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; embryonic viscerocranium morphogenesis [GO:0048703]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; polysaccharide localization [GO:0033037]; post-anal tail morphogenesis [GO:0036342]; post-embryonic development [GO:0009791]; proteoglycan biosynthetic process [GO:0030166]; regulation of cell population proliferation [GO:0042127]; respiratory gaseous exchange by respiratory system [GO:0007585]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0000139; GO:0001537; GO:0001701; GO:0002063; GO:0006915; GO:0007179; GO:0007585; GO:0008146; GO:0009791; GO:0016051; GO:0030166; GO:0030204; GO:0030206; GO:0030326; GO:0030512; GO:0033037; GO:0036342; GO:0042127; GO:0042733; GO:0043066; GO:0047756; GO:0048589; GO:0048703; GO:0048704; GO:0050659; GO:0051216 31385 XM_044325020.1 128 341 153 496 434 NA NA NA NA NA NA 31386 XM_044322074.1 2013 1488 1439 2737 2577 NA NA NA NA NA NA 31387 XM_029328470.2 0 0 41 0 0 NA NA NA NA NA NA 31388 XM_044327339.1 4 0 8 0 13 NA NA NA NA NA NA 31389 XM_044313717.1 0 0 14 0 0 Q9W735 1.58e-86 Prominin-1-A (Prominin-like protein 1) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005783; GO:0005793; GO:0005886; GO:0005902; GO:0005929; GO:0009986; GO:0015485; GO:0016324; GO:0031528; GO:0071914 31390 XM_029345709.2 0 232 75 139 112 NA NA NA NA NA NA 31391 XM_044312482.1 27 22 90 76 42 NA NA NA NA NA NA 31392 XM_044313594.1 76 32 47 62 107 Q5HZE0 1.45e-60 Mitochondrial basic amino acids transporter (Carnitine/acylcarnitine translocase-like) (CACT-like) (Mitochondrial carnitine/acylcarnitine carrier protein CACL) (Mitochondrial ornithine transporter 3) (Solute carrier family 25 member 29) Rattus norvegicus (Rat) acyl carnitine transmembrane transport [GO:1902616]; acyl carnitine transport [GO:0006844]; cation transmembrane transport [GO:0098655]; L-arginine transmembrane transport [GO:1903826]; L-histidine transmembrane transport [GO:0089709]; L-lysine transmembrane transport [GO:1903401]; mitochondrial L-ornithine transmembrane transport [GO:1990575]; organic cation transport [GO:0015695]; ornithine transport [GO:0015822] GO:0005289; GO:0005292; GO:0005739; GO:0005743; GO:0006844; GO:0015174; GO:0015227; GO:0015695; GO:0015822; GO:0022857; GO:0089709; GO:0098655; GO:1902616; GO:1903401; GO:1903826; GO:1990575 31393 XM_029329173.2 935 655 752 743 490 Q8CAE2 1.53e-63 Small RNA 2'-O-methyltransferase (EC 2.1.1.n8) (HEN1 methyltransferase homolog 1) (mHEN1) Mus musculus (Mouse) piRNA processing [GO:0034587]; RNA methylation [GO:0001510]; siRNA processing [GO:0030422] GO:0001510; GO:0003723; GO:0005634; GO:0005737; GO:0005829; GO:0008171; GO:0008173; GO:0030422; GO:0034587; GO:0043186; GO:0046872; GO:0090486 31394 XM_044311310.1 47 21 57 20 104 NA NA NA NA NA NA 31395 XM_029354488.2 4495 3090 2403 6546 2429 Q61153 5.07e-54 Type I iodothyronine deiodinase (EC 1.21.99.4) (5DI) (DIOI) (Type 1 DI) (Type-I 5'-deiodinase) Mus musculus (Mouse) amino acid metabolic process [GO:0006520]; hormone biosynthetic process [GO:0042446]; thyroid hormone metabolic process [GO:0042403] GO:0004800; GO:0005789; GO:0006520; GO:0008430; GO:0042403; GO:0042446 31396 XM_029346615.2 92 175 268 689 523 Q5R7H0 0 2-oxoadipate dehydrogenase complex component E1 (E1a) (OADC-E1) (OADH-E1) (EC 1.2.4.-) (2-oxoadipate dehydrogenase, mitochondrial) (Alpha-ketoadipate dehydrogenase) (Alpha-KADH-E1) (Dehydrogenase E1 and transketolase domain-containing protein 1) (Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) generation of precursor metabolites and energy [GO:0006091]; glycolytic process [GO:0006096]; tricarboxylic acid cycle [GO:0006099] GO:0004591; GO:0005739; GO:0005759; GO:0006091; GO:0006096; GO:0006099; GO:0030976 31397 XM_029344826.2 6286 7202 5133 5807 3387 Q8N138 3.22e-57 ORM1-like protein 3 Homo sapiens (Human) cellular sphingolipid homeostasis [GO:0090156]; ceramide metabolic process [GO:0006672]; motor behavior [GO:0061744]; myelination [GO:0042552]; negative regulation of B cell apoptotic process [GO:0002903]; negative regulation of ceramide biosynthetic process [GO:1900060]; negative regulation of serine C-palmitoyltransferase activity [GO:1904221]; positive regulation of autophagy [GO:0010508]; positive regulation of protein localization to nucleus [GO:1900182]; regulation of smooth muscle contraction [GO:0006940]; sphingolipid biosynthetic process [GO:0030148]; sphingomyelin biosynthetic process [GO:0006686] GO:0002903; GO:0005783; GO:0005789; GO:0005886; GO:0006672; GO:0006686; GO:0006940; GO:0010508; GO:0030148; GO:0030667; GO:0035339; GO:0035579; GO:0042552; GO:0061744; GO:0090156; GO:1900060; GO:1900182; GO:1904221 31398 XM_044325440.1 26 5 0 0 0 NA NA NA NA NA NA 31399 XM_044324850.1 24 22 19 0 26 NA NA NA NA NA NA 31400 XM_044307191.1 7 0 0 1 6 NA NA NA NA NA NA 31401 XM_044319707.1 874 468 235 603 582 Q93Z30 7.63e-26 NA NA NA NA 31402 XR_006391961.1 0 0 0 14 0 NA NA NA NA NA NA 31403 XM_044322395.1 0 206 0 22 0 Q96AY4 6.07e-94 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31404 XM_044322395.1 0 206 0 22 0 Q96AY4 2.49e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31405 XM_044322395.1 0 206 0 22 0 Q96AY4 2.78e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31406 XM_044322395.1 0 206 0 22 0 Q96AY4 2.22e-83 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31407 XM_044322395.1 0 206 0 22 0 Q96AY4 4.22e-83 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31408 XM_044322395.1 0 206 0 22 0 Q96AY4 9.75e-82 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31409 XM_044322395.1 0 206 0 22 0 Q96AY4 2.04e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31410 XM_029332484.2 6 0 3 3 48 NA NA NA NA NA NA 31411 XM_029346748.2 69 319 106 30 41 NA NA NA NA NA NA 31412 XM_029356502.2 332 216 37 0 0 P52275 0 Tubulin beta-2 chain (Beta-2-tubulin) Caenorhabditis elegans meiotic spindle organization [GO:0000212]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278] GO:0000212; GO:0000226; GO:0000278; GO:0003924; GO:0005200; GO:0005525; GO:0005737; GO:0005874; GO:0005876; GO:0045298; GO:0046872 31413 XM_044314456.1 0 5 1 1 317 NA NA NA NA NA NA 31414 XR_006394495.1 38 23 0 1 6 NA NA NA NA NA NA 31415 XR_006391573.1 0 11 15 0 62 NA NA NA NA NA NA 31416 XM_029335175.2 0 75 60 0 105 NA NA NA NA NA NA 31417 XM_044315222.1 13 237 0 0 21 NA NA NA NA NA NA 31418 XM_044314775.1 0 3 0 0 19 NA NA NA NA NA NA 31419 XM_029344928.2 8 10 2 15 10 NA NA NA NA NA NA 31420 XM_044328249.1 2369 2004 1974 2346 2637 Q66PG1 0 Xylosyl- and glucuronyltransferase LARGE2s (EC 2.4.-.-) (Glycosyltransferase-like 1B) (LARGE xylosyl- and glucuronyltransferase 2) [Includes: Alpha-1,3-xylosyltransferase LARGE2 (EC 2.4.2.-); Beta-1,3-glucuronyltransferase LARGE2 (EC 2.4.1.-)] Danio rerio (Zebrafish) (Brachydanio rerio) protein glycosylation [GO:0006486]; protein O-linked mannosylation [GO:0035269] GO:0000139; GO:0005794; GO:0006486; GO:0015020; GO:0035269; GO:0042285; GO:0046872 31421 XM_029350106.2 16 13 25 18 112 NA NA NA NA NA NA 31422 XM_044307058.1 30 5 17 32 18 Q7RTR2 7.95e-57 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 31423 XM_044307058.1 30 5 17 32 18 Q7RTR2 4.19e-52 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 31424 XM_029348537.2 1134 839 553 975 1289 Q6PB03 2.73e-144 5'-3' exonuclease PLD3 (EC 3.1.16.1) (Choline phosphatase 3) (Phosphatidylcholine-hydrolyzing phospholipase D3) (Phospholipase D3) (PLD 3) Xenopus laevis (African clawed frog) immune system process [GO:0002376]; inflammatory response [GO:0006954]; myotube differentiation [GO:0014902]; regulation of cytokine production involved in inflammatory response [GO:1900015] GO:0000139; GO:0002376; GO:0005789; GO:0006954; GO:0014902; GO:0031901; GO:0031902; GO:0043202; GO:0045145; GO:1900015 31425 XM_044318516.1 404 356 98 113 175 Q924L9 4.01e-157 Folylpolyglutamate synthase, mitochondrial (EC 6.3.2.17) (Folylpoly-gamma-glutamate synthetase) (FPGS) (Tetrahydrofolate synthase) (Tetrahydrofolylpolyglutamate synthase) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) one-carbon metabolic process [GO:0006730] GO:0004326; GO:0005524; GO:0005743; GO:0005759; GO:0006730; GO:0046872 31426 XM_044321275.1 24 0 2 20 4 NA NA NA NA NA NA 31427 XM_029335984.2 27 8 29 5 6 Q71RS6 6.98e-106 Sodium/potassium/calcium exchanger 5 (Na(+)/K(+)/Ca(2+)-exchange protein 5) (Solute carrier family 24 member 5) Homo sapiens (Human) calcium ion import [GO:0070509]; calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; melanin biosynthetic process [GO:0042438]; melanocyte differentiation [GO:0030318]; negative regulation of melanin biosynthetic process [GO:0048022]; response to stimulus [GO:0050896] GO:0005262; GO:0005802; GO:0006811; GO:0006874; GO:0008273; GO:0015293; GO:0030318; GO:0032588; GO:0034220; GO:0042438; GO:0042470; GO:0048022; GO:0050896; GO:0070509; GO:0070588 31428 XM_029332388.2 2 10 24 18 29 NA NA NA NA NA NA 31429 XR_003824691.2 24 0 1 9 0 NA NA NA NA NA NA 31430 XR_006396754.1 227 210 415 37 333 NA NA NA NA NA NA 31431 XM_029323875.2 7 1 0 7 0 NA NA NA NA NA NA 31432 XM_029344993.2 214 163 28 99 60 NA NA NA NA NA NA 31433 XM_029350240.2 291 455 177 246 403 Q8AYC9 2.26e-180 Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Checkpoint kinase-1) Gallus gallus (Chicken) cellular response to DNA damage stimulus [GO:0006974]; DNA damage checkpoint signaling [GO:0000077]; DNA repair [GO:0006281]; intracellular signal transduction [GO:0035556]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; negative regulation of mitotic nuclear division [GO:0045839]; peptidyl-threonine phosphorylation [GO:0018107]; protein phosphorylation [GO:0006468]; regulation of double-strand break repair via homologous recombination [GO:0010569]; regulation of histone H3-K9 acetylation [GO:2000615]; regulation of mitotic centrosome separation [GO:0046602]; regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage [GO:0010767]; signal transduction in response to DNA damage [GO:0042770]; transcription initiation-coupled chromatin remodeling [GO:0045815] GO:0000077; GO:0000785; GO:0000794; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0006281; GO:0006468; GO:0006974; GO:0007095; GO:0010569; GO:0010767; GO:0018107; GO:0035402; GO:0035556; GO:0042770; GO:0045815; GO:0045839; GO:0046602; GO:0106310; GO:2000615 31434 XM_029351340.2 526 803 409 1022 732 NA NA NA NA NA NA 31435 XM_044311161.1 0 24 0 19 13 NA NA NA NA NA NA 31436 XM_044320355.1 2 0 0 0 15 NA NA NA NA NA NA 31437 XM_044318193.1 703 539 506 707 833 Q32PW3 0 Transcription initiation factor TFIID subunit 2 (TBP-associated factor 150 kDa) (Transcription initiation factor TFIID 150 kDa subunit) (TAF(II)150) (TAFII-150) (TAFII150) Danio rerio (Zebrafish) (Brachydanio rerio) transcription initiation at RNA polymerase II promoter [GO:0006367] GO:0000976; GO:0003682; GO:0005669; GO:0006367 31438 XM_044316063.1 110 86 51 104 122 O57579 0 Aminopeptidase Ey (EC 3.4.11.20) (Aminopeptidase N) Gallus gallus (Chicken) peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; signal transduction [GO:0007165] GO:0005737; GO:0005886; GO:0006508; GO:0007165; GO:0008217; GO:0008270; GO:0042277; GO:0043171; GO:0070006 31439 XM_029356749.2 22 6 0 6 14 NA NA NA NA NA NA 31440 XM_029355066.2 2 137 39 34 53 NA NA NA NA NA NA 31441 XR_006393976.1 26 0 8 19 106 NA NA NA NA NA NA 31442 XM_029332550.2 0 0 0 20 0 NA NA NA NA NA NA 31443 XM_044320609.1 113 12 47 20 39 NA NA NA NA NA NA 31444 XR_006394759.1 3 23 2 7 6 NA NA NA NA NA NA 31445 XR_003825799.2 15 0 0 53 0 E2QTD3 4.41e-55 Tudor domain-containing protein 5 Canis lupus familiaris (Dog) (Canis familiaris) DNA methylation involved in gamete generation [GO:0043046]; P granule organization [GO:0030719]; piRNA processing [GO:0034587]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283] GO:0007283; GO:0007286; GO:0030719; GO:0033391; GO:0034587; GO:0043046; GO:0043186; GO:0071546 31446 XR_006392949.1 41 2 25 5 151 NA NA NA NA NA NA 31447 XM_029341932.2 275 219 95 181 335 Q6NWD4 9.11e-79 Mitochondrial import inner membrane translocase subunit TIM50 Danio rerio (Zebrafish) (Brachydanio rerio) apoptotic process [GO:0006915]; mitochondrial membrane organization [GO:0007006]; protein dephosphorylation [GO:0006470]; protein import into mitochondrial matrix [GO:0030150] GO:0004722; GO:0004725; GO:0005743; GO:0005744; GO:0006470; GO:0006915; GO:0007006; GO:0030150 31448 XR_006396939.1 33 7 11 17 4 NA NA NA NA NA NA 31449 XM_044320977.1 11 0 9 0 0 Q9VBW3 1.91e-47 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 31450 XM_044313618.1 12 6 14 26 39 NA NA NA NA NA NA 31451 XM_044329347.1 0 0 0 0 21 NA NA NA NA NA NA 31452 XR_006392348.1 11 0 9 19 0 NA NA NA NA NA NA 31453 XM_029357750.2 975 789 702 1215 1195 P52483 2.49e-95 Ubiquitin-conjugating enzyme E2 E3 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme E3) (UbcM2) (Ubiquitin carrier protein E3) (Ubiquitin-conjugating enzyme E2-23 kDa) (Ubiquitin-protein ligase E3) Mus musculus (Mouse) protein K11-linked ubiquitination [GO:0070979]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209] GO:0000209; GO:0004842; GO:0005524; GO:0005634; GO:0005737; GO:0061631; GO:0070534; GO:0070936; GO:0070979 31454 XM_044315787.1 18 0 0 0 0 NA NA NA NA NA NA 31455 XM_029352661.2 45 28 36 41 67 NA NA NA NA NA NA 31456 XM_029341157.2 760 771 497 1692 1040 NA NA NA NA NA NA 31457 XM_044307173.1 8 8 18 13 5 NA NA NA NA NA NA 31458 XM_044320628.1 11 47 0 118 0 NA NA NA NA NA NA 31459 XM_029340943.2 0 0 0 0 129 Q9TRC7 1.91e-173 Amiloride-sensitive amine oxidase [copper-containing] (DAO) (Diamine oxidase) (EC 1.4.3.22) (Amiloride-binding protein 1) (Amine oxidase copper domain-containing protein 1) (Histaminase) Sus scrofa (Pig) amine metabolic process [GO:0009308]; cellular response to azide [GO:0097185]; cellular response to copper ion [GO:0071280]; cellular response to copper ion starvation [GO:0035874]; cellular response to histamine [GO:0071420]; putrescine metabolic process [GO:0009445]; response to antibiotic [GO:0046677] GO:0005507; GO:0005509; GO:0005615; GO:0005886; GO:0005923; GO:0008131; GO:0008201; GO:0008270; GO:0009308; GO:0009445; GO:0035874; GO:0042803; GO:0044877; GO:0046677; GO:0048038; GO:0052597; GO:0052598; GO:0052599; GO:0052600; GO:0070062; GO:0071280; GO:0071420; GO:0097185 31460 XM_029345019.2 182 91 69 104 131 NA NA NA NA NA NA 31461 XM_044319077.1 3816 3811 1615 3303 4215 Q62077 0 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-1) (Phospholipase C-gamma-1) (PLC-gamma-1) Mus musculus (Mouse) calcium ion transport [GO:0006816]; calcium-mediated signaling [GO:0019722]; cell migration [GO:0016477]; cellular response to epidermal growth factor stimulus [GO:0071364]; epidermal growth factor receptor signaling pathway [GO:0007173]; in utero embryonic development [GO:0001701]; inositol trisphosphate biosynthetic process [GO:0032959]; inositol trisphosphate metabolic process [GO:0032957]; modulation of chemical synaptic transmission [GO:0050804]; phosphatidylinositol catabolic process [GO:0031161]; phosphatidylinositol metabolic process [GO:0046488]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; protein secretion [GO:0009306]; regulation of store-operated calcium channel activity [GO:1901339]; response to curcumin [GO:1904643]; response to organonitrogen compound [GO:0010243]; T cell receptor signaling pathway [GO:0050852] GO:0001701; GO:0001726; GO:0004435; GO:0004629; GO:0005158; GO:0005168; GO:0005509; GO:0005737; GO:0005829; GO:0005886; GO:0005911; GO:0006816; GO:0007173; GO:0008180; GO:0009306; GO:0010243; GO:0010634; GO:0016020; GO:0016477; GO:0019722; GO:0019901; GO:0030027; GO:0030136; GO:0030971; GO:0031161; GO:0032587; GO:0032957; GO:0032959; GO:0035254; GO:0042995; GO:0043005; GO:0043536; GO:0045766; GO:0046488; GO:0050429; GO:0050804; GO:0050852; GO:0051219; GO:0051281; GO:0071364; GO:0098685; GO:0098978; GO:1901339; GO:1904643; GO:1905564; GO:2000353 31462 XM_029338852.2 97 297 379 61 626 NA NA NA NA NA NA 31463 XM_029342640.2 834 882 631 877 745 NA NA NA NA NA NA 31464 XM_044320347.1 1962 1282 748 1432 401 P16092 2.12e-110 Fibroblast growth factor receptor 1 (FGFR-1) (bFGF-R-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (MFR) (Proto-oncogene c-Fgr) (CD antigen CD331) Mus musculus (Mouse) angiogenesis [GO:0001525]; auditory receptor cell development [GO:0060117]; blood vessel morphogenesis [GO:0048514]; brain development [GO:0007420]; branching involved in salivary gland morphogenesis [GO:0060445]; calcium ion homeostasis [GO:0055074]; cardiac muscle cell proliferation [GO:0060038]; cell maturation [GO:0048469]; cell population proliferation [GO:0008283]; cementum mineralization [GO:0071529]; central nervous system neuron development [GO:0021954]; chondrocyte differentiation [GO:0002062]; diphosphate metabolic process [GO:0071344]; ear development [GO:0043583]; embryonic limb morphogenesis [GO:0030326]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; gene expression [GO:0010467]; generation of neurons [GO:0048699]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; lung development [GO:0030324]; lung-associated mesenchyme development [GO:0060484]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell proliferation [GO:0010463]; midbrain development [GO:0030901]; middle ear morphogenesis [GO:0042474]; motogenic signaling involved in postnatal olfactory bulb interneuron migration [GO:0021837]; negative regulation of fibroblast growth factor production [GO:0090272]; negative regulation of gene expression [GO:0010629]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron projection development [GO:0031175]; orbitofrontal cortex development [GO:0021769]; organ induction [GO:0001759]; outer ear morphogenesis [GO:0042473]; paraxial mesoderm development [GO:0048339]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of hepatic stellate cell activation [GO:2000491]; positive regulation of inflammatory response [GO:0050729]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway [GO:0090080]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of mitotic cell cycle DNA replication [GO:1903465]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neuron projection development [GO:0010976]; positive regulation of parathyroid hormone secretion [GO:2000830]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; protein autophosphorylation [GO:0046777]; regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling [GO:0060665]; regulation of cell population proliferation [GO:0042127]; regulation of epithelial cell proliferation [GO:0050678]; regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001239]; regulation of gene expression [GO:0010468]; regulation of lateral mesodermal cell fate specification [GO:0048378]; regulation of phosphate transport [GO:0010966]; regulation of phosphorus metabolic process [GO:0051174]; regulation of sensory perception of pain [GO:0051930]; regulation of stem cell proliferation [GO:0072091]; response to sodium phosphate [GO:1904383]; salivary gland morphogenesis [GO:0007435]; sensory perception of sound [GO:0007605]; stem cell differentiation [GO:0048863]; stem cell population maintenance [GO:0019827]; stem cell proliferation [GO:0072089]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; vasculogenesis involved in coronary vascular morphogenesis [GO:0060979]; ventricular zone neuroblast division [GO:0021847]; vitamin D3 metabolic process [GO:0070640] GO:0000122; GO:0001525; GO:0001657; GO:0001701; GO:0001759; GO:0001837; GO:0002053; GO:0002062; GO:0004713; GO:0004714; GO:0005007; GO:0005102; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0007169; GO:0007420; GO:0007435; GO:0007605; GO:0008201; GO:0008283; GO:0008284; GO:0008543; GO:0010463; GO:0010467; GO:0010468; GO:0010629; GO:0010763; GO:0010863; GO:0010966; GO:0010976; GO:0017134; GO:0018108; GO:0019827; GO:0021769; GO:0021837; GO:0021847; GO:0021954; GO:0030324; GO:0030326; GO:0030901; GO:0031175; GO:0031410; GO:0033674; GO:0035607; GO:0042127; GO:0042169; GO:0042472; GO:0042473; GO:0042474; GO:0042802; GO:0042803; GO:0043235; GO:0043406; GO:0043410; GO:0043536; GO:0043583; GO:0044877; GO:0045597; GO:0045666; GO:0045668; GO:0045787; GO:0045944; GO:0046777; GO:0048339; GO:0048378; GO:0048469; GO:0048471; GO:0048514; GO:0048699; GO:0048762; GO:0048863; GO:0050678; GO:0050729; GO:0050839; GO:0051174; GO:0051897; GO:0051930; GO:0055074; GO:0060038; GO:0060045; GO:0060117; GO:0060445; GO:0060484; GO:0060665; GO:0060979; GO:0070640; GO:0071344; GO:0071529; GO:0072089; GO:0072091; GO:0090080; GO:0090272; GO:0090722; GO:1903465; GO:1904383; GO:1905564; GO:2000491; GO:2000546; GO:2000648; GO:2000830; GO:2001239 31465 XM_029340755.2 18 0 12 14 44 P21674 1.05e-37 Follistatin (FS) (Activin-binding protein) Rattus norvegicus (Rat) ameloblast differentiation [GO:0036305]; BMP signaling pathway [GO:0030509]; cell differentiation [GO:0030154]; cellular response to growth factor stimulus [GO:0071363]; female gonad development [GO:0008585]; gamete generation [GO:0007276]; hair follicle morphogenesis [GO:0031069]; hematopoietic progenitor cell differentiation [GO:0002244]; keratinocyte proliferation [GO:0043616]; negative regulation of activin receptor signaling pathway [GO:0032926]; negative regulation of cell differentiation [GO:0045596]; negative regulation of epithelial cell differentiation [GO:0030857]; negative regulation of follicle-stimulating hormone secretion [GO:0046882]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis of dentin-containing tooth [GO:0042475]; pattern specification process [GO:0007389]; positive regulation of hair follicle development [GO:0051798]; regulation of BMP signaling pathway [GO:0030510]; response to organic cyclic compound [GO:0014070]; skeletal system development [GO:0001501] GO:0000122; GO:0001501; GO:0002244; GO:0005615; GO:0005634; GO:0005737; GO:0007276; GO:0007389; GO:0008585; GO:0014070; GO:0030154; GO:0030509; GO:0030510; GO:0030857; GO:0031069; GO:0032926; GO:0036305; GO:0038102; GO:0042475; GO:0043395; GO:0043616; GO:0045596; GO:0046882; GO:0048185; GO:0051798; GO:0071363 31466 XM_044309012.1 104 140 67 0 0 NA NA NA NA NA NA 31467 XM_044327770.1 237 275 143 254 315 NA NA NA NA NA NA 31468 XM_029347671.2 723 39 141 250 47 Q0P5B1 3.98e-27 Peroxisomal membrane protein PEX13 (Peroxin-13) Bos taurus (Bovine) cerebral cortex cell migration [GO:0021795]; fatty acid alpha-oxidation [GO:0001561]; locomotory behavior [GO:0007626]; microtubule-based peroxisome localization [GO:0060152]; neuron migration [GO:0001764]; protein import into peroxisome matrix, docking [GO:0016560]; suckling behavior [GO:0001967] GO:0001561; GO:0001764; GO:0001967; GO:0005778; GO:0007626; GO:0008320; GO:0016560; GO:0021795; GO:0060152; GO:1990429 31469 XM_044313262.1 53 253 95 86 125 NA NA NA NA NA NA 31470 XM_044319701.1 79 0 0 35 41 NA NA NA NA NA NA 31471 XM_044323501.1 19 14 5 24 42 NA NA NA NA NA NA 31472 XM_029337922.2 731 463 600 811 875 O54826 3.78e-98 Protein AF-10 Mus musculus (Mouse) histone H3-K27 methylation [GO:0070734]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0003682; GO:0005634; GO:0005654; GO:0006357; GO:0031491; GO:0032991; GO:0042393; GO:0045944; GO:0046872; GO:0070734 31473 XM_044308272.1 465 30 170 126 248 Q5XGM3 4.96e-154 Betaine--homocysteine S-methyltransferase 1 (EC 2.1.1.5) Xenopus laevis (African clawed frog) amino-acid betaine catabolic process [GO:0006579]; methionine biosynthetic process [GO:0009086]; methylation [GO:0032259] GO:0005737; GO:0006579; GO:0008270; GO:0009086; GO:0032259; GO:0047150 31474 XM_044321874.1 819 698 447 641 936 A7MBJ2 9.02e-77 Sentrin-specific protease 7 (EC 3.4.22.-) (SUMO-1-specific protease 2) (Sentrin/SUMO-specific protease SENP7) Bos taurus (Bovine) antiviral innate immune response [GO:0140374]; protein desumoylation [GO:0016926] GO:0005634; GO:0005737; GO:0016926; GO:0070139; GO:0140374 31475 XM_029331914.2 35 0 0 0 0 Q6B858 9.87e-96 Fibronectin type 3 and ankyrin repeat domains protein 1 (GV14) Bos taurus (Bovine) positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of apoptotic process [GO:0042981] GO:0005634; GO:0005829; GO:0005929; GO:0036064; GO:0042981; GO:0045893; GO:0051091 31476 XR_006393590.1 799 140 988 272 3560 NA NA NA NA NA NA 31477 XM_029343686.2 4489 2875 2048 3067 2090 P31401 0 V-type proton ATPase subunit B (V-ATPase subunit B) (Vacuolar proton pump subunit B) Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm) ATP metabolic process [GO:0046034] GO:0005524; GO:0033180; GO:0046034; GO:0046961 31478 XM_044310461.1 391 899 500 2011 918 NA NA NA NA NA NA 31479 XR_006394864.1 481 225 356 286 415 NA NA NA NA NA NA 31480 XM_029335257.2 333 233 256 308 315 Q8BTH6 9.62e-70 Transcriptional repressor scratch 2 (Scratch homolog 2 zinc finger protein) Mus musculus (Mouse) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355]; regulation of neuron migration [GO:2001222] GO:0000122; GO:0000978; GO:0000981; GO:0005634; GO:0006355; GO:0046872; GO:1990837; GO:2001222 31481 XM_044326502.1 9 0 0 2 4 NA NA NA NA NA NA 31482 XM_029350836.2 276 234 191 310 287 Q7T0P7 1.62e-58 Mitochondrial inner membrane protease ATP23 homolog (EC 3.4.24.-) Xenopus laevis (African clawed frog) proteolysis [GO:0006508] GO:0004222; GO:0006508; GO:0046872 31483 XM_029332113.2 180 93 92 167 280 O75899 3.11e-145 Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51) (HG20) Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway [GO:0007186]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; neuron-glial cell signaling [GO:0150099]; synaptic transmission, GABAergic [GO:0051932] GO:0004888; GO:0004965; GO:0005737; GO:0005886; GO:0007186; GO:0007193; GO:0007194; GO:0007214; GO:0007268; GO:0038039; GO:0043005; GO:0045211; GO:0046982; GO:0051932; GO:0150099; GO:1902710; GO:1902712 31484 XR_003824957.2 14 29 18 66 19 NA NA NA NA NA NA 31485 XM_044320980.1 1165 1063 822 912 1803 Q9NRY5 1.74e-55 Protein FAM114A2 Homo sapiens (Human) NA GO:0017076 31486 XM_044309093.1 0 0 61 4 0 Q14974 3.64e-94 Importin subunit beta-1 (Importin-90) (Karyopherin subunit beta-1) (Nuclear factor p97) (Pore targeting complex 97 kDa subunit) (PTAC97) Homo sapiens (Human) astral microtubule organization [GO:0030953]; establishment of mitotic spindle localization [GO:0040001]; establishment of protein localization [GO:0045184]; mitotic chromosome movement towards spindle pole [GO:0007079]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly [GO:0090307]; NLS-bearing protein import into nucleus [GO:0006607]; protein import into nucleus [GO:0006606]; Ran protein signal transduction [GO:0031291]; ribosomal protein import into nucleus [GO:0006610]; RNA import into nucleus [GO:0006404] GO:0003723; GO:0005576; GO:0005634; GO:0005635; GO:0005643; GO:0005654; GO:0005737; GO:0005829; GO:0006404; GO:0006606; GO:0006607; GO:0006610; GO:0007079; GO:0007080; GO:0008139; GO:0008270; GO:0010494; GO:0016020; GO:0019899; GO:0019904; GO:0030953; GO:0031267; GO:0031291; GO:0031965; GO:0035580; GO:0040001; GO:0042564; GO:0045184; GO:0051879; GO:0061608; GO:0061676; GO:0070062; GO:0071782; GO:0090307; GO:1904813 31487 XM_044320061.1 217 69 162 106 275 D3Z5L6 2.51e-63 MFS-type transporter SLC18B1 (Solute carrier family 18 member B1) (Vesicular polyamine transporter) (VPAT) Mus musculus (Mouse) serotonin transport [GO:0006837]; serotonin uptake [GO:0051610]; spermidine transport [GO:0015848]; spermine transport [GO:0000296] GO:0000296; GO:0006837; GO:0015311; GO:0015312; GO:0015848; GO:0022857; GO:0030667; GO:0030672; GO:0051610 31488 XM_044308087.1 0 86 132 281 0 Q92113 1.21e-136 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Squalus acanthias (Spiny dogfish) steroid biosynthetic process [GO:0006694] GO:0004508; GO:0005506; GO:0006694; GO:0016020; GO:0020037; GO:0047442 31489 XM_044324418.1 7 5 0 50 0 NA NA NA NA NA NA 31490 XM_029332495.2 0 8 0 11 26 NA NA NA NA NA NA 31491 XM_044309533.1 0 7 10 9 27 Q95218 2.64e-56 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 31492 XM_044309533.1 0 7 10 9 27 Q95218 7.98e-56 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 31493 XM_044309533.1 0 7 10 9 27 Q95218 7.75e-55 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 31494 XM_044309533.1 0 7 10 9 27 Q95218 3.48e-54 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 31495 XM_044309533.1 0 7 10 9 27 Q95218 1.56e-52 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 31496 XM_044309533.1 0 7 10 9 27 Q95218 4.7e-51 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 31497 XM_044309533.1 0 7 10 9 27 Q95218 3.64e-28 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 31498 XM_044309533.1 0 7 10 9 27 Q95218 1.95e-26 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 31499 XM_044309533.1 0 7 10 9 27 Q95218 1.03e-24 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 31500 XM_044309533.1 0 7 10 9 27 Q95218 1.12e-24 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 31501 XM_029353874.2 9 6 6 3 20 NA NA NA NA NA NA 31502 XR_006396936.1 5 3 23 8 1 Q96DM1 2.08e-27 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 31503 XR_006396936.1 5 3 23 8 1 Q96DM1 2.08e-27 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 31504 XM_044322482.1 27 23 4 0 12 NA NA NA NA NA NA 31505 XR_006392287.1 0 0 0 70 0 NA NA NA NA NA NA 31506 XM_044320649.1 0 17 0 5 20 NA NA NA NA NA NA 31507 XR_006392638.1 15 0 0 11 0 NA NA NA NA NA NA 31508 XM_044312487.1 0 0 0 2 16 NA NA NA NA NA NA 31509 XM_029342736.2 6254 3860 3839 7885 6213 Q64487 0 Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48) Mus musculus (Mouse) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; neuron differentiation [GO:0030182]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse assembly [GO:0051965]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; regulation of immune response [GO:0050776]; regulation of postsynaptic density assembly [GO:0099151]; synaptic membrane adhesion [GO:0099560]; trans-synaptic signaling [GO:0099537]; trans-synaptic signaling by trans-synaptic complex [GO:0099545] GO:0004725; GO:0005102; GO:0006470; GO:0007157; GO:0030182; GO:0042734; GO:0046426; GO:0050775; GO:0050776; GO:0050804; GO:0050839; GO:0051965; GO:0097105; GO:0098685; GO:0098686; GO:0098978; GO:0099054; GO:0099151; GO:0099537; GO:0099545; GO:0099560 31510 XM_029342736.2 6254 3860 3839 7885 6213 Q64487 1.3e-123 Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48) Mus musculus (Mouse) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; neuron differentiation [GO:0030182]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse assembly [GO:0051965]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; regulation of immune response [GO:0050776]; regulation of postsynaptic density assembly [GO:0099151]; synaptic membrane adhesion [GO:0099560]; trans-synaptic signaling [GO:0099537]; trans-synaptic signaling by trans-synaptic complex [GO:0099545] GO:0004725; GO:0005102; GO:0006470; GO:0007157; GO:0030182; GO:0042734; GO:0046426; GO:0050775; GO:0050776; GO:0050804; GO:0050839; GO:0051965; GO:0097105; GO:0098685; GO:0098686; GO:0098978; GO:0099054; GO:0099151; GO:0099537; GO:0099545; GO:0099560 31511 XM_029342736.2 6254 3860 3839 7885 6213 Q64487 3.29e-38 Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48) Mus musculus (Mouse) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; neuron differentiation [GO:0030182]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse assembly [GO:0051965]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; regulation of immune response [GO:0050776]; regulation of postsynaptic density assembly [GO:0099151]; synaptic membrane adhesion [GO:0099560]; trans-synaptic signaling [GO:0099537]; trans-synaptic signaling by trans-synaptic complex [GO:0099545] GO:0004725; GO:0005102; GO:0006470; GO:0007157; GO:0030182; GO:0042734; GO:0046426; GO:0050775; GO:0050776; GO:0050804; GO:0050839; GO:0051965; GO:0097105; GO:0098685; GO:0098686; GO:0098978; GO:0099054; GO:0099151; GO:0099537; GO:0099545; GO:0099560 31512 XM_044314716.1 47 39 17 177 15 NA NA NA NA NA NA 31513 XM_029358390.2 1955 870 803 1357 693 Q9VYY9 2.89e-126 Ecotropic viral integration site 5 ortholog Drosophila melanogaster (Fruit fly) activation of GTPase activity [GO:0090630]; regulation of cell migration [GO:0030334]; regulation of GTPase activity [GO:0043087]; regulation of protein localization [GO:0032880] GO:0005096; GO:0005737; GO:0005768; GO:0005794; GO:0030334; GO:0031267; GO:0031982; GO:0032880; GO:0043087; GO:0090630 31514 XM_044325348.1 0 0 0 0 10 P48733 1.76e-28 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Bos taurus (Bovine) antibacterial innate immune response [GO:0140367]; defense response to Gram-negative bacterium [GO:0050829] GO:0000922; GO:0005201; GO:0005509; GO:0005576; GO:0005929; GO:0016020; GO:0016323; GO:0016324; GO:0031012; GO:0050829; GO:0060170; GO:0140367 31515 XM_029343928.2 419 441 243 288 240 NA NA NA NA NA NA 31516 XR_006391354.1 21 16 32 47 19 NA NA NA NA NA NA 31517 XM_029329907.2 806 820 460 750 671 P48052 1.06e-100 Carboxypeptidase A2 (EC 3.4.17.15) Homo sapiens (Human) protein catabolic process in the vacuole [GO:0007039]; proteolysis [GO:0006508] GO:0004180; GO:0004181; GO:0005576; GO:0005615; GO:0005773; GO:0006508; GO:0007039; GO:0008270 31518 XR_006396368.1 38 0 0 17 17 NA NA NA NA NA NA 31519 XM_029349816.2 3774 6835 1500 3631 2986 Q3ZC71 3.47e-23 Dolichol-phosphate mannosyltransferase subunit 3 (Dolichol-phosphate mannose synthase subunit 3) (DPM synthase subunit 3) (Dolichyl-phosphate beta-D-mannosyltransferase subunit 3) (Mannose-P-dolichol synthase subunit 3) (MPD synthase subunit 3) Bos taurus (Bovine) dolichol metabolic process [GO:0019348]; GPI anchor biosynthetic process [GO:0006506]; protein glycosylation [GO:0006486]; regulation of protein stability [GO:0031647] GO:0005789; GO:0006486; GO:0006506; GO:0008047; GO:0019348; GO:0031647; GO:0033185 31520 XM_044314894.1 64 12 39 40 100 NA NA NA NA NA NA 31521 XM_029354648.2 466 230 108 153 234 Q7ZWY2 3.59e-86 PIH1 domain-containing protein 1 Xenopus laevis (African clawed frog) NA GO:0005634 31522 XM_029347862.2 2 18 1 6 29 NA NA NA NA NA NA 31523 XR_006392347.1 1 0 9 15 1 NA NA NA NA NA NA 31524 XR_006394102.1 13 0 8 9 0 NA NA NA NA NA NA 31525 XM_029336598.2 27 4 7 20 8 NA NA NA NA NA NA 31526 XR_003826403.2 23 6 7 16 11 NA NA NA NA NA NA 31527 XM_044316656.1 92 17 26 35 39 P11617 7.28e-24 Adenosine receptor A2a Canis lupus familiaris (Dog) (Canis familiaris) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; apoptotic signaling pathway [GO:0097190]; eating behavior [GO:0042755]; G protein-coupled adenosine receptor signaling pathway [GO:0001973]; G protein-coupled receptor signaling pathway [GO:0007186]; inhibitory postsynaptic potential [GO:0060080]; locomotory behavior [GO:0007626]; negative regulation of alpha-beta T cell activation [GO:0046636]; negative regulation of inflammatory response [GO:0050728]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; response to amphetamine [GO:0001975]; response to inorganic substance [GO:0010035]; response to purine-containing compound [GO:0014074]; synaptic transmission, dopaminergic [GO:0001963] GO:0001609; GO:0001963; GO:0001973; GO:0001975; GO:0004930; GO:0005886; GO:0007186; GO:0007189; GO:0007626; GO:0008289; GO:0010035; GO:0014074; GO:0019899; GO:0032230; GO:0042755; GO:0042802; GO:0046636; GO:0050728; GO:0060080; GO:0097190; GO:0098794; GO:2001235 31528 XM_044311831.1 27 30 27 3 59 Q13308 5.58e-68 Inactive tyrosine-protein kinase 7 (Colon carcinoma kinase 4) (CCK-4) (Protein-tyrosine kinase 7) (Pseudo tyrosine kinase receptor 7) (Tyrosine-protein kinase-like 7) Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; axis elongation [GO:0003401]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to retinoic acid [GO:0071300]; cochlea morphogenesis [GO:0090103]; convergent extension [GO:0060026]; coronary vasculature development [GO:0060976]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of planar polarity [GO:0001736]; kidney development [GO:0001822]; lung-associated mesenchyme development [GO:0060484]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of neuron projection development [GO:0010976]; protein phosphorylation [GO:0006468]; regulation of canonical Wnt signaling pathway [GO:0060828]; signal transduction [GO:0007165]; ventricular septum development [GO:0003281]; wound healing [GO:0042060] GO:0001736; GO:0001822; GO:0003281; GO:0003401; GO:0004672; GO:0005524; GO:0005886; GO:0005911; GO:0005925; GO:0006468; GO:0007155; GO:0007165; GO:0010976; GO:0016477; GO:0031532; GO:0042060; GO:0045198; GO:0050839; GO:0060026; GO:0060484; GO:0060828; GO:0060976; GO:0071300; GO:0090103; GO:0090179; GO:0090263; GO:1904929 31529 XM_029344362.2 28 1796 479 2299 1278 Q5XJ85 5.56e-27 Myeloid differentiation primary response protein MyD88 Danio rerio (Zebrafish) (Brachydanio rerio) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; monocyte activation [GO:0042117]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; neutrophil activation involved in immune response [GO:0002283]; neutrophil chemotaxis [GO:0030593]; positive regulation of hematopoietic progenitor cell differentiation [GO:1901534]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of hematopoietic progenitor cell differentiation [GO:1901532]; response to molecule of bacterial origin [GO:0002237]; Toll signaling pathway [GO:0008063] GO:0002218; GO:0002237; GO:0002283; GO:0002755; GO:0005737; GO:0005886; GO:0006954; GO:0008063; GO:0030593; GO:0035325; GO:0042117; GO:0042742; GO:0043123; GO:0045087; GO:0050830; GO:0070976; GO:1901532; GO:1901534 31530 XM_044328276.1 1082 868 777 844 1017 Q16960 2.09e-29 Dynein intermediate chain 3, ciliary Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina) NA GO:0005737; GO:0005874; GO:0005929; GO:0030286 31531 XM_044318668.1 214 25 194 143 467 O75899 1.34e-71 Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51) (HG20) Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway [GO:0007186]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; neuron-glial cell signaling [GO:0150099]; synaptic transmission, GABAergic [GO:0051932] GO:0004888; GO:0004965; GO:0005737; GO:0005886; GO:0007186; GO:0007193; GO:0007194; GO:0007214; GO:0007268; GO:0038039; GO:0043005; GO:0045211; GO:0046982; GO:0051932; GO:0150099; GO:1902710; GO:1902712 31532 XM_044323655.1 1 2 12 5 2 Q568B7 1.18e-35 Glycosyltransferase-like domain-containing protein 1 Danio rerio (Zebrafish) (Brachydanio rerio) central nervous system development [GO:0007417] GO:0007417; GO:0016757 31533 XM_029350115.2 113 28 6 74 27 NA NA NA NA NA NA 31534 XM_044314525.1 3 0 2 7 3 NA NA NA NA NA NA 31535 XR_003824517.2 1427 1186 923 1029 1149 NA NA NA NA NA NA 31536 XM_029331897.2 1138 863 632 1161 867 NA NA NA NA NA NA 31537 XM_044316439.1 0 3 7 12 8 NA NA NA NA NA NA 31538 XR_006397412.1 3 4 13 0 0 NA NA NA NA NA NA 31539 XM_044313130.1 758 600 464 743 749 NA NA NA NA NA NA 31540 XM_044314532.1 2 0 17 15 6 Q80XJ3 3.08e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 31541 XM_029350883.2 874 836 444 934 865 Q9NUQ7 1.76e-124 Ufm1-specific protease 2 (UfSP2) (EC 3.4.22.-) Homo sapiens (Human) proteolysis [GO:0006508]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146] GO:0005634; GO:0005737; GO:0005783; GO:0006508; GO:0033146; GO:0071567 31542 XM_029335038.2 2235 1700 1359 1761 883 Q6GQN5 9.08e-84 Protein phosphatase 1 regulatory subunit 42 (Leucine-rich repeat-containing protein 67) Danio rerio (Zebrafish) (Brachydanio rerio) positive regulation of protein dephosphorylation [GO:0035307] GO:0000164; GO:0002177; GO:0003779; GO:0004865; GO:0005813; GO:0005815; GO:0015630; GO:0015631; GO:0035307; GO:0070840 31543 XM_029333415.2 2085 1184 1085 1505 1788 Q8K4G6 1.38e-69 ADP-ribose glycohydrolase MACROD1 (MACRO domain-containing protein 1) (O-acetyl-ADP-ribose deacetylase MACROD1) (EC 3.1.1.106) (Protein LRP16) ([Protein ADP-ribosylaspartate] hydrolase MACROD1) (EC 3.2.2.-) ([Protein ADP-ribosylglutamate] hydrolase MACROD1) (EC 3.2.2.-) Rattus norvegicus (Rat) cellular response to DNA damage stimulus [GO:0006974]; peptidyl-glutamate ADP-deribosylation [GO:0140291]; protein de-ADP-ribosylation [GO:0051725]; purine nucleoside metabolic process [GO:0042278] GO:0005634; GO:0005654; GO:0006974; GO:0016798; GO:0019213; GO:0042278; GO:0051725; GO:0140291; GO:0140293 31544 XM_029342445.2 128 345 324 1256 981 B9EJV3 6.84e-122 GREB1-like protein Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cardiac ventricle development [GO:0003231]; epithelial tube morphogenesis [GO:0060562]; kidney development [GO:0001822]; male genitalia development [GO:0030539]; mesonephric duct development [GO:0072177]; metanephros development [GO:0001656]; paramesonephric duct development [GO:0061205]; uterus development [GO:0060065] GO:0001656; GO:0001658; GO:0001822; GO:0003231; GO:0016020; GO:0030539; GO:0060065; GO:0060562; GO:0061205; GO:0072177 31545 XM_029342445.2 128 345 324 1256 981 B9EJV3 5.48e-96 GREB1-like protein Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cardiac ventricle development [GO:0003231]; epithelial tube morphogenesis [GO:0060562]; kidney development [GO:0001822]; male genitalia development [GO:0030539]; mesonephric duct development [GO:0072177]; metanephros development [GO:0001656]; paramesonephric duct development [GO:0061205]; uterus development [GO:0060065] GO:0001656; GO:0001658; GO:0001822; GO:0003231; GO:0016020; GO:0030539; GO:0060065; GO:0060562; GO:0061205; GO:0072177 31546 XM_029342445.2 128 345 324 1256 981 B9EJV3 7.64e-42 GREB1-like protein Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cardiac ventricle development [GO:0003231]; epithelial tube morphogenesis [GO:0060562]; kidney development [GO:0001822]; male genitalia development [GO:0030539]; mesonephric duct development [GO:0072177]; metanephros development [GO:0001656]; paramesonephric duct development [GO:0061205]; uterus development [GO:0060065] GO:0001656; GO:0001658; GO:0001822; GO:0003231; GO:0016020; GO:0030539; GO:0060065; GO:0060562; GO:0061205; GO:0072177 31547 XR_006397927.1 0 0 33 16 23 P48441 0 Alpha-L-iduronidase (EC 3.2.1.76) Mus musculus (Mouse) adult locomotory behavior [GO:0008344]; adult walking behavior [GO:0007628]; bone development [GO:0060348]; carbohydrate metabolic process [GO:0005975]; cartilage homeostasis [GO:1990079]; cell morphogenesis [GO:0000902]; chemical homeostasis [GO:0048878]; dermatan sulfate catabolic process [GO:0030209]; extracellular matrix organization [GO:0030198]; glycosaminoglycan catabolic process [GO:0006027]; heparan sulfate proteoglycan catabolic process [GO:0030200]; heparin catabolic process [GO:0030211]; limb morphogenesis [GO:0035108]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; memory [GO:0007613]; negative regulation of cartilage development [GO:0061037]; negative regulation of secretion of lysosomal enzymes [GO:0090341]; positive regulation of bone resorption [GO:0045780]; positive regulation of collagen catabolic process [GO:0120158]; skeletal system morphogenesis [GO:0048705]; visual learning [GO:0008542] GO:0000902; GO:0003940; GO:0004553; GO:0005102; GO:0005615; GO:0005764; GO:0005975; GO:0006027; GO:0007040; GO:0007613; GO:0007626; GO:0007628; GO:0008344; GO:0008542; GO:0030135; GO:0030198; GO:0030200; GO:0030209; GO:0030211; GO:0035108; GO:0043202; GO:0045780; GO:0048705; GO:0048878; GO:0060348; GO:0061037; GO:0090341; GO:0120158; GO:1990079 31548 XM_044326044.1 192 47 79 66 197 P33450 3.8e-30 Cadherin-related tumor suppressor (Protein fat) [Cleaved into: Ft-mito] Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; equator specification [GO:0045317]; establishment of body hair planar orientation [GO:0048105]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; establishment or maintenance of polarity of larval imaginal disc epithelium [GO:0016336]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; imaginal disc-derived wing morphogenesis [GO:0007476]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of growth [GO:0045926]; negative regulation of imaginal disc growth [GO:0045571]; negative regulation of organ growth [GO:0046621]; positive regulation of apoptotic process [GO:0043065]; positive regulation of hippo signaling [GO:0035332]; protein localization involved in establishment of planar polarity [GO:0090251]; pupal development [GO:0035209]; regulation of establishment of planar polarity [GO:0090175]; regulation of growth [GO:0040008]; regulation of imaginal disc growth [GO:0045570]; regulation of protein localization [GO:0032880]; regulation of tube length, open tracheal system [GO:0035159]; tissue development [GO:0009888]; wing disc development [GO:0035220] GO:0001736; GO:0001737; GO:0005509; GO:0005739; GO:0005886; GO:0007156; GO:0007157; GO:0007164; GO:0007446; GO:0007447; GO:0007476; GO:0008285; GO:0009888; GO:0010629; GO:0016324; GO:0016327; GO:0016336; GO:0016339; GO:0032880; GO:0035159; GO:0035209; GO:0035220; GO:0035332; GO:0040008; GO:0042067; GO:0043065; GO:0044331; GO:0045296; GO:0045317; GO:0045570; GO:0045571; GO:0045926; GO:0046621; GO:0048105; GO:0090175; GO:0090176; GO:0090251; GO:0098609 31549 XM_044324179.1 1230 468 674 842 876 Q80X08 1.54e-46 WASH complex subunit 2 Rattus norvegicus (Rat) endocytic recycling [GO:0032456]; negative regulation of barbed-end actin filament capping [GO:2000813]; protein localization to endosome [GO:0036010]; regulation of substrate adhesion-dependent cell spreading [GO:1900024]; retrograde transport, endosome to Golgi [GO:0042147] GO:0005546; GO:0005547; GO:0005768; GO:0005769; GO:0005829; GO:0005886; GO:0010314; GO:0031901; GO:0032266; GO:0032456; GO:0036010; GO:0042147; GO:0043325; GO:0070273; GO:0071203; GO:0080025; GO:1900024; GO:1901981; GO:1905394; GO:2000813 31550 XM_029327409.2 1018 811 588 771 722 NA NA NA NA NA NA 31551 XM_029336885.2 6 0 0 8 3 NA NA NA NA NA NA 31552 XM_029347707.2 4 0 0 0 56 NA NA NA NA NA NA 31553 XR_003824099.2 18 40 86 83 53 NA NA NA NA NA NA 31554 XM_029350313.2 46 41 12 16 84 Q96AY4 4.8e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31555 XM_029354360.2 0 7 2 0 40 B8VIU6 4.06e-37 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 31556 XM_044322144.1 0 0 0 64 238 A7T1N0 0 Transient receptor potential cation channel subfamily M member-like 2 (nvTRPM2) Nematostella vectensis (Starlet sea anemone) calcium ion transmembrane transport [GO:0070588]; cation transmembrane transport [GO:0098655]; sodium ion transmembrane transport [GO:0035725] GO:0005261; GO:0005886; GO:0015280; GO:0035725; GO:0046872; GO:0047631; GO:0070588; GO:0098655; GO:0099604 31557 XM_044318215.1 52 18 42 63 116 NA NA NA NA NA NA 31558 XM_029333233.2 173 102 66 150 133 Q8N6Q8 2.46e-56 Probable methyltransferase-like protein 25 (EC 2.1.1.-) Homo sapiens (Human) methylation [GO:0032259] GO:0008168; GO:0032259 31559 XM_029339265.2 15 0 0 52 42 Q9N2B7 4.29e-39 5-hydroxytryptamine receptor 1B (5-HT-1B) (5-HT1B) (Serotonin receptor 1B) Gorilla gorilla gorilla (Western lowland gorilla) adenylate cyclase-inhibiting serotonin receptor signaling pathway [GO:0007198]; behavior [GO:0007610]; bone remodeling [GO:0046849]; cellular response to alkaloid [GO:0071312]; cellular response to xenobiotic stimulus [GO:0071466]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; negative regulation of serotonin secretion [GO:0014063]; regulation of behavior [GO:0050795]; vasoconstriction [GO:0042310] GO:0004993; GO:0005886; GO:0007187; GO:0007198; GO:0007268; GO:0007610; GO:0014063; GO:0030425; GO:0030594; GO:0042310; GO:0045202; GO:0046849; GO:0050795; GO:0051378; GO:0071312; GO:0071466 31560 XR_006393133.1 430 1779 199 634 0 NA NA NA NA NA NA 31561 XR_006394648.1 202 88 89 208 590 NA NA NA NA NA NA 31562 XM_044318997.1 58 7 47 27 243 Q9I830 7.94e-86 Potassium voltage-gated channel subfamily A member 2 (Shaker-related potassium channel tsha1) (Trout shaker 1) (Voltage-gated potassium channel subunit Kv1.2) Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) neuronal action potential [GO:0019228]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005251; GO:0005886; GO:0008076; GO:0019228; GO:0034765; GO:0044224; GO:0051260; GO:0071805 31563 XM_044315105.1 46 48 49 46 149 Q91175 7.8e-47 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (MAR1) Oryzias latipes (Japanese rice fish) (Japanese killifish) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of vasoconstriction [GO:0045907] GO:0001996; GO:0004930; GO:0004937; GO:0005886; GO:0007200; GO:0007204; GO:0007267; GO:0043410; GO:0045907; GO:0071880 31564 XM_044324800.1 898 1053 669 1541 2111 P29144 0 Tripeptidyl-peptidase 2 (TPP-2) (EC 3.4.14.10) (Tripeptidyl aminopeptidase) (Tripeptidyl-peptidase II) (TPP-II) Homo sapiens (Human) cellular amino acid homeostasis [GO:0080144]; protein polyubiquitination [GO:0000209]; proteolysis [GO:0006508] GO:0000209; GO:0004175; GO:0004177; GO:0004252; GO:0005654; GO:0005737; GO:0005829; GO:0006508; GO:0008240; GO:0016604; GO:0042802; GO:0080144 31565 XM_044308060.1 576 161 101 81 374 NA NA NA NA NA NA 31566 XM_029329020.2 111 153 99 77 25 Q96GG9 4e-131 DCN1-like protein 1 (DCNL1) (DCUN1 domain-containing protein 1) (Defective in cullin neddylation protein 1-like protein 1) (Squamous cell carcinoma-related oncogene) Homo sapiens (Human) positive regulation of protein neddylation [GO:2000436]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein neddylation [GO:0045116]; regulation of protein neddylation [GO:2000434]; regulation of protein ubiquitination [GO:0031396] GO:0000151; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0031396; GO:0031624; GO:0032182; GO:0045116; GO:0051443; GO:0097602; GO:2000434; GO:2000436 31567 XM_029356677.2 23457 29493 23614 27019 18536 Q6AZJ9 8.18e-36 40S ribosomal protein S21 Xenopus laevis (African clawed frog) cytoplasmic translation [GO:0002181] GO:0002181; GO:0003735; GO:0005791; GO:0022627; GO:0042788 31568 XR_006395289.1 8216 7717 3363 8985 4414 NA NA NA NA NA NA 31569 XR_006392641.1 10 20 4 2 37 NA NA NA NA NA NA 31570 XM_029334979.2 135 85 79 192 179 NA NA NA NA NA NA 31571 XM_044327509.1 329 65 421 365 601 NA NA NA NA NA NA 31572 XM_044312549.1 131 0 34 86 12 Q8K3P0 1.95e-72 Short-chain dehydrogenase/reductase family 9C member 7 (EC 1.1.1.-) (Orphan short-chain dehydrogenase/reductase) (SDR-O) (RDH-S) Mus musculus (Mouse) retinol metabolic process [GO:0042572]; steroid metabolic process [GO:0008202] GO:0004745; GO:0005737; GO:0008202; GO:0016491; GO:0042572; GO:0043231 31573 XR_006393414.1 10 1 3 31 14 NA NA NA NA NA NA 31574 XM_029350586.2 3 3 9 3 8 NA NA NA NA NA NA 31575 XM_029340408.2 1299 1373 722 1950 1228 Q9NYT6 2.06e-40 Zinc finger protein 226 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 31576 XM_029340408.2 1299 1373 722 1950 1228 Q9NYT6 4.6e-24 Zinc finger protein 226 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 31577 XM_029342122.2 3430 2359 1578 3415 3039 P97479 0 Unconventional myosin-VIIa Mus musculus (Mouse) actin filament organization [GO:0007015]; actin filament-based movement [GO:0030048]; auditory receptor cell stereocilium organization [GO:0060088]; cell projection organization [GO:0030030]; equilibrioception [GO:0050957]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear development [GO:0048839]; inner ear morphogenesis [GO:0042472]; inner ear receptor cell differentiation [GO:0060113]; inner ear receptor cell stereocilium organization [GO:0060122]; intracellular protein transport [GO:0006886]; lysosome organization [GO:0007040]; mechanoreceptor differentiation [GO:0042490]; phagocytosis [GO:0006909]; phagolysosome assembly [GO:0001845]; pigment granule localization [GO:0051875]; pigment granule transport [GO:0051904]; post-embryonic animal organ morphogenesis [GO:0048563]; protein localization [GO:0008104]; sensory organ development [GO:0007423]; sensory perception [GO:0007600]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; vesicle transport along actin filament [GO:0030050]; visual perception [GO:0007601] GO:0000146; GO:0001750; GO:0001845; GO:0001917; GO:0003774; GO:0003779; GO:0005516; GO:0005524; GO:0005737; GO:0005765; GO:0005829; GO:0005902; GO:0005938; GO:0006886; GO:0006909; GO:0007015; GO:0007040; GO:0007423; GO:0007600; GO:0007601; GO:0007605; GO:0008104; GO:0015629; GO:0016324; GO:0016459; GO:0019904; GO:0030030; GO:0030048; GO:0030050; GO:0030507; GO:0031477; GO:0031982; GO:0032391; GO:0032420; GO:0042470; GO:0042472; GO:0042490; GO:0042491; GO:0042802; GO:0043531; GO:0044877; GO:0045202; GO:0047485; GO:0048563; GO:0048839; GO:0050953; GO:0050957; GO:0051015; GO:0051875; GO:0051904; GO:0060088; GO:0060113; GO:0060122; GO:0120044; GO:1990435 31578 XM_029330545.2 497 613 922 537 622 Q6AZN0 6.9e-104 Dynein axonemal assembly factor 4 Xenopus laevis (African clawed frog) cilium movement [GO:0003341]; nervous system development [GO:0007399] GO:0003341; GO:0005634; GO:0007399; GO:0043005; GO:0120293 31579 XM_044324192.1 1998 1546 1322 2178 1739 NA NA NA NA NA NA 31580 XM_044326041.1 6 3 9 5 0 P49887 7.83e-26 Sulfotransferase 1E1 (ST1E1) (EC 2.8.2.4) (Estrogen sulfotransferase) (ST1E3) (Sulfotransferase, estrogen-preferring) Cavia porcellus (Guinea pig) 3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; estrogen catabolic process [GO:0006711]; estrogen metabolic process [GO:0008210]; ethanol catabolic process [GO:0006068]; positive regulation of fat cell differentiation [GO:0045600]; sulfation [GO:0051923] GO:0004304; GO:0005496; GO:0005829; GO:0006068; GO:0006711; GO:0008210; GO:0031965; GO:0045600; GO:0047894; GO:0050294; GO:0050427; GO:0051923 31581 XR_003824644.2 0 15 22 0 0 NA NA NA NA NA NA 31582 XM_044316331.1 441 0 3 139 75 NA NA NA NA NA NA 31583 XR_006397296.1 0 7 3 29 3 NA NA NA NA NA NA 31584 XM_044318588.1 352 345 304 564 516 P0CI65 9.43e-54 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 31585 XM_044318588.1 352 345 304 564 516 P0CI65 7.54e-51 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 31586 XM_044318588.1 352 345 304 564 516 P0CI65 8.5e-51 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 31587 XM_044318588.1 352 345 304 564 516 P0CI65 1.06e-47 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 31588 XM_029337741.2 952 908 665 1764 439 O46560 7.06e-118 Pyridoxal kinase (EC 2.7.1.35) (Pyridoxine kinase) Sus scrofa (Pig) phosphorylation [GO:0016310]; pyridoxal 5'-phosphate salvage [GO:0009443] GO:0005524; GO:0005829; GO:0008478; GO:0009443; GO:0016310; GO:0046872 31589 XM_029330677.2 473 632 333 899 225 Q13951 4.08e-56 Core-binding factor subunit beta (CBF-beta) (Polyomavirus enhancer-binding protein 2 beta subunit) (PEA2-beta) (PEBP2-beta) (SL3-3 enhancer factor 1 subunit beta) (SL3/AKV core-binding factor beta subunit) Homo sapiens (Human) cell maturation [GO:0048469]; definitive hemopoiesis [GO:0060216]; lymphocyte differentiation [GO:0030098]; myeloid cell differentiation [GO:0030099]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of transcription by RNA polymerase II [GO:0000122]; osteoblast differentiation [GO:0001649]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein polyubiquitination [GO:0000209]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366] GO:0000122; GO:0000209; GO:0001649; GO:0003713; GO:0005654; GO:0006357; GO:0006366; GO:0016020; GO:0016513; GO:0030098; GO:0030099; GO:0043371; GO:0043378; GO:0043565; GO:0045944; GO:0048469; GO:0060216 31590 XR_003824702.2 46 66 33 31 53 NA NA NA NA NA NA 31591 XM_029328909.2 0 0 0 0 6 NA NA NA NA NA NA 31592 XM_044314011.1 0 0 2 11 0 NA NA NA NA NA NA 31593 XM_029358376.2 88 66 87 89 187 NA NA NA NA NA NA 31594 XM_044311066.1 0 0 0 10 0 NA NA NA NA NA NA 31595 XM_029323857.2 74 45 52 92 72 Q566X8 1.42e-25 Diencephalon/mesencephalon homeobox protein 1-B Danio rerio (Zebrafish) (Brachydanio rerio) midbrain development [GO:0030901]; regulation of cell cycle [GO:0051726]; regulation of mitotic cell cycle [GO:0007346]; regulation of neural retina development [GO:0061074]; regulation of neurogenesis [GO:0050767]; regulation of transcription by RNA polymerase II [GO:0006357]; retina development in camera-type eye [GO:0060041] GO:0000977; GO:0000981; GO:0005634; GO:0006357; GO:0007346; GO:0030901; GO:0050767; GO:0051726; GO:0060041; GO:0061074 31596 XM_044318902.1 0 497 0 0 27 Q5RD26 2.56e-63 Heterogeneous nuclear ribonucleoprotein H2 (hnRNP H2) (Heterogeneous nuclear ribonucleoprotein H') (hnRNP H') [Cleaved into: Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed] Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003723; GO:0005654; GO:1990904 31597 XM_044328726.1 0 0 0 55 34 NA NA NA NA NA NA 31598 XM_044313080.1 410 285 376 300 343 O94766 1.59e-100 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 (EC 2.4.1.135) (Beta-1,3-glucuronyltransferase 3) (Glucuronosyltransferase I) (GlcAT-I) (UDP-GlcUA:Gal beta-1,3-Gal-R glucuronyltransferase) (GlcUAT-I) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; chondroitin sulfate proteoglycan biosynthetic process [GO:0050650]; dermatan sulfate proteoglycan biosynthetic process [GO:0050651]; glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; positive regulation of catalytic activity [GO:0043085]; positive regulation of intracellular protein transport [GO:0090316]; protein glycosylation [GO:0006486] GO:0000139; GO:0005794; GO:0005801; GO:0005975; GO:0006024; GO:0006486; GO:0015012; GO:0015018; GO:0015020; GO:0016020; GO:0043085; GO:0046872; GO:0050650; GO:0050651; GO:0070062; GO:0072542; GO:0090316 31599 XM_044313555.1 1316 639 651 992 1164 B0S6T2 2.73e-155 Solute carrier family 15 member 2 (Peptide transporter 2) (PEPT2) Danio rerio (Zebrafish) (Brachydanio rerio) dipeptide import across plasma membrane [GO:0140206]; innate immune response [GO:0045087]; peptidoglycan transport [GO:0015835]; protein transport [GO:0015031]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424]; response to yeast [GO:0001878]; transmembrane transport [GO:0055085] GO:0001878; GO:0005886; GO:0015031; GO:0015293; GO:0015835; GO:0016020; GO:0022857; GO:0045087; GO:0055085; GO:0070424; GO:0071916; GO:0140206 31600 XM_029346697.2 1026 383 242 844 706 NA NA NA NA NA NA 31601 XR_006392722.1 16 0 0 7 30 NA NA NA NA NA NA 31602 XR_006396431.1 14 8 13 0 14 NA NA NA NA NA NA 31603 XM_029342991.2 1502 2071 1221 2886 508 Q9JID6 0 Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3) (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain acyl-CoA synthetase 1) (LACS 1) (Palmitoyl-CoA ligase) (Phytanate--CoA ligase) (EC 6.2.1.24) Cavia porcellus (Guinea pig) long-chain fatty acid metabolic process [GO:0001676]; very long-chain fatty acid metabolic process [GO:0000038] GO:0000038; GO:0001676; GO:0004467; GO:0005524; GO:0005741; GO:0005778; GO:0005783; GO:0005789; GO:0047676; GO:0050197; GO:0070251 31604 XM_044326922.1 3 10 0 13 19 P53610 2.67e-82 Geranylgeranyl transferase type-1 subunit beta (EC 2.5.1.59) (Geranylgeranyl transferase type I subunit beta) (GGTase-I-beta) (Type I protein geranyl-geranyltransferase subunit beta) Rattus norvegicus (Rat) negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; protein geranylgeranylation [GO:0018344]; protein prenylation [GO:0018342]; response to cytokine [GO:0034097] GO:0004661; GO:0004662; GO:0005953; GO:0008270; GO:0008284; GO:0018342; GO:0018344; GO:0034097; GO:0045787; GO:0051771; GO:1901363 31605 XM_044326922.1 3 10 0 13 19 P53610 2.67e-82 Geranylgeranyl transferase type-1 subunit beta (EC 2.5.1.59) (Geranylgeranyl transferase type I subunit beta) (GGTase-I-beta) (Type I protein geranyl-geranyltransferase subunit beta) Rattus norvegicus (Rat) negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; protein geranylgeranylation [GO:0018344]; protein prenylation [GO:0018342]; response to cytokine [GO:0034097] GO:0004661; GO:0004662; GO:0005953; GO:0008270; GO:0008284; GO:0018342; GO:0018344; GO:0034097; GO:0045787; GO:0051771; GO:1901363 31606 XR_003828427.2 891 270 625 1360 460 NA NA NA NA NA NA 31607 XR_006396722.1 30 22 26 25 50 NA NA NA NA NA NA 31608 XM_029334657.2 666 696 258 284 431 O32210 8.57e-75 Glyoxal reductase (GR) (EC 1.1.1.-) (Methylglyoxal reductase) (EC 1.1.1.283) Bacillus subtilis (strain 168) NA GO:0043892 31609 XM_029330444.2 1369 1121 471 559 681 NA NA NA NA NA NA 31610 XR_006393674.1 18 3 43 11 149 NA NA NA NA NA NA 31611 XM_029327435.2 202 218 99 122 244 A5A761 8.77e-150 Sideroflexin-1 Sus scrofa (Pig) L-alanine transport [GO:0015808]; L-serine transport [GO:0015825]; mitochondrial transmembrane transport [GO:1990542]; one-carbon metabolic process [GO:0006730]; serine import into mitochondrion [GO:0140300] GO:0005743; GO:0006730; GO:0015180; GO:0015194; GO:0015808; GO:0015825; GO:0022857; GO:0022889; GO:0140300; GO:1990542 31612 XR_006393122.1 1 137 86 116 232 NA NA NA NA NA NA 31613 XM_029343384.2 3573 3289 2151 2700 3080 P58197 6.03e-80 Transcription factor AP-2-alpha (AP2-alpha) (AP-2 transcription factor) (Activating enhancer-binding protein 2-alpha) (Activator protein 2) (AP-2) Rattus norvegicus (Rat) anatomical structure development [GO:0048856]; anterior neuropore closure [GO:0021506]; basement membrane organization [GO:0071711]; bone morphogenesis [GO:0060349]; cell population proliferation [GO:0008283]; cellular response to iron ion [GO:0071281]; cornea development in camera-type eye [GO:0061303]; embryonic body morphogenesis [GO:0010172]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic forelimb morphogenesis [GO:0035115]; embryonic pattern specification [GO:0009880]; epidermal growth factor receptor signaling pathway [GO:0007173]; epidermis morphogenesis [GO:0048730]; eyelid development in camera-type eye [GO:0061029]; face morphogenesis [GO:0060325]; fibroblast migration [GO:0010761]; forebrain neuron development [GO:0021884]; forelimb morphogenesis [GO:0035136]; inner ear morphogenesis [GO:0042472]; keratinocyte development [GO:0003334]; kidney development [GO:0001822]; lens induction in camera-type eye [GO:0060235]; lens morphogenesis in camera-type eye [GO:0002089]; metanephric nephron development [GO:0072210]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of transcription by competitive promoter binding [GO:0010944]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; neural crest cell development [GO:0014032]; neural tube closure [GO:0001843]; neuron apoptotic process [GO:0051402]; oculomotor nerve formation [GO:0021623]; optic cup structural organization [GO:0003409]; optic vesicle morphogenesis [GO:0003404]; outflow tract morphogenesis [GO:0003151]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of tooth mineralization [GO:0070172]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; regulation of DNA-templated transcription [GO:0006355]; regulation of neuron differentiation [GO:0045664]; regulation of transcription by RNA polymerase II [GO:0006357]; response to lipopolysaccharide [GO:0032496]; response to water deprivation [GO:0009414]; retina layer formation [GO:0010842]; roof of mouth development [GO:0060021]; Schwann cell development [GO:0014044]; sensory organ development [GO:0007423]; sensory perception of sound [GO:0007605]; skeletal system morphogenesis [GO:0048705]; skin development [GO:0043588]; sympathetic nervous system development [GO:0048485]; transcription by RNA polymerase II [GO:0006366]; trigeminal nerve development [GO:0021559] GO:0000122; GO:0000976; GO:0000977; GO:0000978; GO:0000981; GO:0000987; GO:0001227; GO:0001228; GO:0001822; GO:0001843; GO:0002089; GO:0003151; GO:0003334; GO:0003404; GO:0003409; GO:0003677; GO:0003682; GO:0003700; GO:0003713; GO:0003714; GO:0005634; GO:0005905; GO:0006355; GO:0006357; GO:0006366; GO:0007173; GO:0007399; GO:0007423; GO:0007605; GO:0008283; GO:0008285; GO:0009414; GO:0009880; GO:0010172; GO:0010628; GO:0010761; GO:0010763; GO:0010842; GO:0010944; GO:0014032; GO:0014044; GO:0021506; GO:0021559; GO:0021623; GO:0021884; GO:0030335; GO:0030501; GO:0032496; GO:0035115; GO:0035136; GO:0042059; GO:0042127; GO:0042472; GO:0042802; GO:0043066; GO:0043524; GO:0043525; GO:0043565; GO:0043588; GO:0045595; GO:0045664; GO:0045892; GO:0045893; GO:0045944; GO:0048485; GO:0048596; GO:0048701; GO:0048705; GO:0048730; GO:0048856; GO:0051402; GO:0060021; GO:0060235; GO:0060325; GO:0060349; GO:0061029; GO:0061303; GO:0070172; GO:0071281; GO:0071711; GO:0072210; GO:0140536; GO:1990837; GO:2000378 31614 XM_029347531.2 52 70 54 62 112 NA NA NA NA NA NA 31615 XM_044310108.1 283 177 209 446 295 NA NA NA NA NA NA 31616 XM_044313035.1 12 6 6 20 21 Q80XJ3 5.16e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 31617 XM_044313035.1 12 6 6 20 21 Q80XJ3 2.5e-51 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 31618 XM_044313035.1 12 6 6 20 21 Q80XJ3 3.65e-48 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 31619 XM_044313035.1 12 6 6 20 21 Q80XJ3 2.47e-47 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 31620 XM_044313035.1 12 6 6 20 21 Q80XJ3 1.77e-46 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 31621 XM_044313035.1 12 6 6 20 21 Q80XJ3 1.6e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 31622 XM_044313035.1 12 6 6 20 21 Q80XJ3 1.11e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 31623 XM_044313035.1 12 6 6 20 21 Q80XJ3 1.04e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 31624 XM_044313035.1 12 6 6 20 21 Q80XJ3 4.04e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 31625 XM_044313035.1 12 6 6 20 21 Q80XJ3 1.34e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 31626 XM_044313035.1 12 6 6 20 21 Q80XJ3 1.43e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 31627 XM_044313035.1 12 6 6 20 21 Q80XJ3 5.23e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 31628 XM_044313035.1 12 6 6 20 21 Q80XJ3 6.68e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 31629 XM_044313035.1 12 6 6 20 21 Q80XJ3 2.44e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 31630 XM_044327598.1 4 7 6 14 21 P81274 1.35e-54 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 31631 XM_044327598.1 4 7 6 14 21 P81274 1.37e-49 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 31632 XM_044327598.1 4 7 6 14 21 P81274 1.45e-46 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 31633 XM_044327598.1 4 7 6 14 21 P81274 4.73e-40 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 31634 XM_044327598.1 4 7 6 14 21 P81274 2.83e-24 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 31635 XM_044326503.1 51 10 25 65 44 NA NA NA NA NA NA 31636 XM_044323111.1 289 298 236 600 348 Q9CR50 3.48e-25 RING finger and CHY zinc finger domain-containing protein 1 (EC 2.3.2.27) (Androgen receptor N-terminal-interacting protein) (CH-rich-interacting match with PLAG1) (E3 ubiquitin-protein ligase Pirh2) (RING-type E3 ubiquitin transferase RCHY1) (Zinc finger protein 363) Mus musculus (Mouse) positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; protein autoubiquitination [GO:0051865]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000151; GO:0002039; GO:0005102; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006511; GO:0008270; GO:0016567; GO:0016607; GO:0031398; GO:0032436; GO:0042803; GO:0043231; GO:0051865; GO:0061630 31637 XM_029324794.2 4078 1251 1199 1832 1398 NA NA NA NA NA NA 31638 XM_029343033.2 175 0 0 376 325 NA NA NA NA NA NA 31639 XR_006397026.1 64 49 16 86 57 NA NA NA NA NA NA 31640 XM_044322190.1 339 290 131 337 262 Q9SEE4 2.7e-71 Pirin-like protein Solanum lycopersicum (Tomato) (Lycopersicon esculentum) NA GO:0005634 31641 XM_029355563.2 4 0 1 0 9 P48040 7.06e-27 Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor) Ovis aries (Sheep) NA GO:0005886; GO:0008502 31642 XM_029335691.2 14 116 48 43 86 P21555 1.32e-21 Neuropeptide Y receptor type 1 (NPY1-R) (FC5) Rattus norvegicus (Rat) aging [GO:0007568]; feeding behavior [GO:0007631]; glucose metabolic process [GO:0006006]; locomotory behavior [GO:0007626]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of hormone secretion [GO:0046888]; neuropeptide signaling pathway [GO:0007218]; outflow tract morphogenesis [GO:0003151]; peristalsis [GO:0030432]; positive regulation of vasoconstriction [GO:0045907]; regulation of blood pressure [GO:0008217]; regulation of multicellular organism growth [GO:0040014]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to estradiol [GO:0032355]; sensory perception of pain [GO:0019233]; synaptic signaling via neuropeptide [GO:0099538] GO:0001601; GO:0001602; GO:0003151; GO:0004983; GO:0005829; GO:0005886; GO:0006006; GO:0007218; GO:0007568; GO:0007626; GO:0007631; GO:0008021; GO:0008188; GO:0008217; GO:0019233; GO:0030424; GO:0030432; GO:0032355; GO:0040014; GO:0042734; GO:0042923; GO:0043005; GO:0045907; GO:0046888; GO:0051481; GO:0098978; GO:0098992; GO:0099509; GO:0099538; GO:2000300 31643 XM_044328529.1 695 681 278 1055 542 Q6L8S8 2.52e-57 Beta-1,4-N-acetylgalactosaminyltransferase 3 (Beta4GalNAc-T3) (Beta4GalNAcT3) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase III) (N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 2) (NGalNAc-T2) Mus musculus (Mouse) chondroitin sulfate biosynthetic process [GO:0030206] GO:0005794; GO:0008376; GO:0030206; GO:0032580; GO:0033842; GO:0043231; GO:0047238 31644 XM_029340971.2 270 187 309 270 0 NA NA NA NA NA NA 31645 XM_029355478.2 3238 2104 1626 3030 2327 P10894 0 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (EC 3.1.4.11) (PLC-154) (Phosphoinositide phospholipase C-beta-1) (Phospholipase C-beta-1) (PLC-beta-1) Bos taurus (Bovine) interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-15-mediated signaling pathway [GO:0035723]; lipid catabolic process [GO:0016042]; memory [GO:0007613]; phosphatidylinositol metabolic process [GO:0046488]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of JNK cascade [GO:0046330] GO:0004435; GO:0005096; GO:0005509; GO:0005516; GO:0005546; GO:0005737; GO:0005829; GO:0007613; GO:0016042; GO:0016607; GO:0019899; GO:0031965; GO:0035722; GO:0035723; GO:0046330; GO:0046488; GO:0048015; GO:0070498 31646 XM_044319449.1 16 5 5 2 0 NA NA NA NA NA NA 31647 XM_044312156.1 212 136 2 80 50 NA NA NA NA NA NA 31648 XM_029337528.2 1087 895 709 836 1004 A3KPA3 1.84e-73 N-alpha-acetyltransferase 60 (EC 2.3.1.259) (Histone acetyltransferase type B protein 4) (HAT4) (EC 2.3.1.48) (N-acetyltransferase 15) (N-alpha-acetyltransferase F) (NatF) Danio rerio (Zebrafish) (Brachydanio rerio) cell population proliferation [GO:0008283]; chromosome segregation [GO:0007059]; histone H3 acetylation [GO:0043966]; histone H4 acetylation [GO:0043967]; N-terminal peptidyl-methionine acetylation [GO:0017196]; N-terminal protein amino acid acetylation [GO:0006474]; nucleosome assembly [GO:0006334] GO:0000139; GO:0004402; GO:0004596; GO:0006334; GO:0006474; GO:0007059; GO:0008283; GO:0010485; GO:0017196; GO:0042803; GO:0043966; GO:0043967 31649 XM_044309219.1 4 11 0 3 4 NA NA NA NA NA NA 31650 XM_044329073.1 370 497 643 1702 443 P46222 9.73e-104 60S ribosomal protein L11 Drosophila melanogaster (Fruit fly) cytoplasmic translation [GO:0002181] GO:0002181; GO:0003723; GO:0003735; GO:0005730; GO:0005737; GO:0019843; GO:0022625; GO:0022626 31651 XM_044307796.1 76 2 42 76 46 NA NA NA NA NA NA 31652 XR_006396138.1 0 0 13 0 0 NA NA NA NA NA NA 31653 XM_029358544.2 100 153 120 142 78 NA NA NA NA NA NA 31654 XM_044308298.1 4429 3861 3532 5483 5420 NA NA NA NA NA NA 31655 XM_029325951.2 0 213 2 0 0 NA NA NA NA NA NA 31656 XM_029358514.2 60 8 11 52 16 P16092 1.01e-83 Fibroblast growth factor receptor 1 (FGFR-1) (bFGF-R-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (MFR) (Proto-oncogene c-Fgr) (CD antigen CD331) Mus musculus (Mouse) angiogenesis [GO:0001525]; auditory receptor cell development [GO:0060117]; blood vessel morphogenesis [GO:0048514]; brain development [GO:0007420]; branching involved in salivary gland morphogenesis [GO:0060445]; calcium ion homeostasis [GO:0055074]; cardiac muscle cell proliferation [GO:0060038]; cell maturation [GO:0048469]; cell population proliferation [GO:0008283]; cementum mineralization [GO:0071529]; central nervous system neuron development [GO:0021954]; chondrocyte differentiation [GO:0002062]; diphosphate metabolic process [GO:0071344]; ear development [GO:0043583]; embryonic limb morphogenesis [GO:0030326]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; gene expression [GO:0010467]; generation of neurons [GO:0048699]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; lung development [GO:0030324]; lung-associated mesenchyme development [GO:0060484]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell proliferation [GO:0010463]; midbrain development [GO:0030901]; middle ear morphogenesis [GO:0042474]; motogenic signaling involved in postnatal olfactory bulb interneuron migration [GO:0021837]; negative regulation of fibroblast growth factor production [GO:0090272]; negative regulation of gene expression [GO:0010629]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron projection development [GO:0031175]; orbitofrontal cortex development [GO:0021769]; organ induction [GO:0001759]; outer ear morphogenesis [GO:0042473]; paraxial mesoderm development [GO:0048339]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of hepatic stellate cell activation [GO:2000491]; positive regulation of inflammatory response [GO:0050729]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway [GO:0090080]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of mitotic cell cycle DNA replication [GO:1903465]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neuron projection development [GO:0010976]; positive regulation of parathyroid hormone secretion [GO:2000830]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; protein autophosphorylation [GO:0046777]; regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling [GO:0060665]; regulation of cell population proliferation [GO:0042127]; regulation of epithelial cell proliferation [GO:0050678]; regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001239]; regulation of gene expression [GO:0010468]; regulation of lateral mesodermal cell fate specification [GO:0048378]; regulation of phosphate transport [GO:0010966]; regulation of phosphorus metabolic process [GO:0051174]; regulation of sensory perception of pain [GO:0051930]; regulation of stem cell proliferation [GO:0072091]; response to sodium phosphate [GO:1904383]; salivary gland morphogenesis [GO:0007435]; sensory perception of sound [GO:0007605]; stem cell differentiation [GO:0048863]; stem cell population maintenance [GO:0019827]; stem cell proliferation [GO:0072089]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; vasculogenesis involved in coronary vascular morphogenesis [GO:0060979]; ventricular zone neuroblast division [GO:0021847]; vitamin D3 metabolic process [GO:0070640] GO:0000122; GO:0001525; GO:0001657; GO:0001701; GO:0001759; GO:0001837; GO:0002053; GO:0002062; GO:0004713; GO:0004714; GO:0005007; GO:0005102; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0007169; GO:0007420; GO:0007435; GO:0007605; GO:0008201; GO:0008283; GO:0008284; GO:0008543; GO:0010463; GO:0010467; GO:0010468; GO:0010629; GO:0010763; GO:0010863; GO:0010966; GO:0010976; GO:0017134; GO:0018108; GO:0019827; GO:0021769; GO:0021837; GO:0021847; GO:0021954; GO:0030324; GO:0030326; GO:0030901; GO:0031175; GO:0031410; GO:0033674; GO:0035607; GO:0042127; GO:0042169; GO:0042472; GO:0042473; GO:0042474; GO:0042802; GO:0042803; GO:0043235; GO:0043406; GO:0043410; GO:0043536; GO:0043583; GO:0044877; GO:0045597; GO:0045666; GO:0045668; GO:0045787; GO:0045944; GO:0046777; GO:0048339; GO:0048378; GO:0048469; GO:0048471; GO:0048514; GO:0048699; GO:0048762; GO:0048863; GO:0050678; GO:0050729; GO:0050839; GO:0051174; GO:0051897; GO:0051930; GO:0055074; GO:0060038; GO:0060045; GO:0060117; GO:0060445; GO:0060484; GO:0060665; GO:0060979; GO:0070640; GO:0071344; GO:0071529; GO:0072089; GO:0072091; GO:0090080; GO:0090272; GO:0090722; GO:1903465; GO:1904383; GO:1905564; GO:2000491; GO:2000546; GO:2000648; GO:2000830; GO:2001239 31657 XR_003827138.2 678 396 332 676 651 NA NA NA NA NA NA 31658 XM_029326703.2 180 542 100 2529 2981 NA NA NA NA NA NA 31659 XM_029352290.2 2 2 0 0 11 Q6GNJ8 4.6e-42 Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) Xenopus laevis (African clawed frog) regulation of DNA-templated transcription [GO:0006355]; transcription initiation-coupled chromatin remodeling [GO:0045815] GO:0003677; GO:0005634; GO:0006355; GO:0045815; GO:0140713; GO:0140849 31660 XM_029357162.2 136 173 131 87 158 NA NA NA NA NA NA 31661 XM_044320519.1 119 17 82 0 264 A0A1L8FZ98 2.97e-65 Peroxisome biogenesis factor 2 (EC 2.3.2.27) (EC 2.3.2.36) (Peroxin-2) Xenopus laevis (African clawed frog) pexophagy [GO:0000425]; protein import into peroxisome matrix, receptor recycling [GO:0016562]; response to amino acid starvation [GO:1990928] GO:0000425; GO:0005778; GO:0016562; GO:0046872; GO:0061630; GO:1990928 31662 XM_029332416.2 1207 1034 859 1101 1121 A0JNH6 2.25e-70 Coiled-coil domain-containing protein 102A Bos taurus (Bovine) NA GO:0016459 31663 XM_044322186.1 129 72 138 105 378 NA NA NA NA NA NA 31664 XM_044322391.1 118 105 38 69 70 NA NA NA NA NA NA 31665 XM_044317384.1 38 706 61 348 260 NA NA NA NA NA NA 31666 XM_044321774.1 0 0 0 0 27 NA NA NA NA NA NA 31667 XM_029332660.2 17 9 3 5 4 G3M4F8 7.06e-21 Octopamine receptor beta-2R (CsOA2B2) Chilo suppressalis (Asiatic rice borer moth) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cellular response to amine stimulus [GO:0071418]; octopamine signaling pathway [GO:0071927]; tyramine signaling pathway [GO:0071928] GO:0004989; GO:0005886; GO:0007189; GO:0008226; GO:0016020; GO:0071418; GO:0071927; GO:0071928 31668 XM_044309361.1 0 0 0 0 35 NA NA NA NA NA NA 31669 XR_006393691.1 19 0 6 12 17 NA NA NA NA NA NA 31670 XM_044324610.1 86 24 20 46 37 NA NA NA NA NA NA 31671 XM_029326504.2 23 3 7 8 25 NA NA NA NA NA NA 31672 XM_044319146.1 204 48 88 294 178 NA NA NA NA NA NA 31673 XM_044316737.1 0 0 29 19 4 NA NA NA NA NA NA 31674 XM_044320183.1 283 62 65 183 132 NA NA NA NA NA NA 31675 XM_044317628.1 159 0 0 0 0 Q5RHH4 0 Intraflagellar transport protein 172 homolog Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; intraciliary transport [GO:0042073]; photoreceptor cell maintenance [GO:0045494]; pronephros development [GO:0048793]; regulation of TOR signaling [GO:0032006]; retina development in camera-type eye [GO:0060041] GO:0005929; GO:0005930; GO:0030992; GO:0032006; GO:0036064; GO:0042073; GO:0045494; GO:0048793; GO:0060041; GO:0060271 31676 XM_044310574.1 39 28 44 29 75 NA NA NA NA NA NA 31677 XM_029344590.2 859 888 707 1162 2017 P22033 0 Methylmalonyl-CoA mutase, mitochondrial (MCM) (EC 5.4.99.2) (Methylmalonyl-CoA isomerase) Homo sapiens (Human) homocysteine metabolic process [GO:0050667]; positive regulation of GTPase activity [GO:0043547]; post-embryonic development [GO:0009791]; propionate metabolic process, methylmalonyl pathway [GO:0019678]; succinyl-CoA biosynthetic process [GO:1901290] GO:0003924; GO:0004494; GO:0005737; GO:0005739; GO:0005759; GO:0009791; GO:0019678; GO:0031419; GO:0042802; GO:0042803; GO:0043547; GO:0046872; GO:0050667; GO:0072341; GO:1901290 31678 XM_029332814.2 139 0 9 6 0 Q8TC07 2.47e-33 TBC1 domain family member 15 (GTPase-activating protein RAB7) (GAP for RAB7) (Rab7-GAP) Homo sapiens (Human) activation of GTPase activity [GO:0090630]; regulation of GTPase activity [GO:0043087] GO:0005096; GO:0005576; GO:0005737; GO:0043087; GO:0090630 31679 XM_044317119.1 68 134 302 78 24 NA NA NA NA NA NA 31680 XM_044328837.1 0 0 0 10 9 P20825 1.08e-69 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 31681 XM_029339894.2 417 315 111 212 141 A2VE56 2.22e-31 PHD finger protein 20-like protein 1 Bos taurus (Bovine) histone acetylation [GO:0016573]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0005634; GO:0006357; GO:0016573; GO:0044545 31682 XM_029348606.2 556 283 196 162 261 A6U882 4.75e-23 30S ribosomal protein S11 Sinorhizobium medicae (strain WSM419) (Ensifer medicae) translation [GO:0006412] GO:0003735; GO:0005840; GO:0006412; GO:0019843; GO:1990904 31683 XM_029344581.2 1708 1931 844 1289 1255 Q5F495 2.5e-125 MOB-like protein phocein (Mob1 homolog 3) (Mob3) (Mps one binder kinase activator-like 3) (Preimplantation protein 3) Gallus gallus (Chicken) NA GO:0005737; GO:0032580; GO:0046872 31684 XR_003827556.2 0 5 15 13 86 NA NA NA NA NA NA 31685 XR_006396586.1 11 32 10 42 16 NA NA NA NA NA NA 31686 XM_029338444.2 157 251 163 233 222 Q9CXS4 2.21e-55 Centromere protein V (CENP-V) (Proline-rich protein 6) Mus musculus (Mouse) ameboidal-type cell migration [GO:0001667]; cell cycle [GO:0007049]; cell division [GO:0051301]; centromere complex assembly [GO:0034508]; pericentric heterochromatin formation [GO:0031508]; positive regulation of cytokinesis [GO:0032467]; regulation of chromosome organization [GO:0033044] GO:0000776; GO:0001667; GO:0005634; GO:0005654; GO:0005829; GO:0007049; GO:0015630; GO:0016846; GO:0030496; GO:0031508; GO:0031965; GO:0032467; GO:0033044; GO:0034508; GO:0046872; GO:0051233; GO:0051301 31687 XM_044326665.1 3 3 1 3 21 NA NA NA NA NA NA 31688 XM_044315850.1 67 22 22 27 46 Q80XJ3 9.06e-78 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 31689 XM_044315850.1 67 22 22 27 46 Q80XJ3 5.01e-76 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 31690 XM_044315850.1 67 22 22 27 46 Q80XJ3 1.83e-72 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 31691 XM_044315850.1 67 22 22 27 46 Q80XJ3 1.84e-71 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 31692 XM_044315850.1 67 22 22 27 46 Q80XJ3 2.46e-69 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 31693 XM_044315850.1 67 22 22 27 46 Q80XJ3 8.89e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 31694 XM_044319862.1 99 66 62 35 98 Q8MIQ9 8.33e-97 P protein (Melanocyte-specific transporter protein) (Pink-eyed dilution protein homolog) Sus scrofa (Pig) lysosomal lumen pH elevation [GO:0035752]; melanin biosynthetic process [GO:0042438]; melanin biosynthetic process from tyrosine [GO:0006583]; melanocyte differentiation [GO:0030318] GO:0006583; GO:0030318; GO:0033162; GO:0035752; GO:0042438; GO:0061778 31695 XM_029326985.2 2878 2803 1888 4140 4151 P41035 9.32e-103 Eukaryotic translation initiation factor 2 subunit 2 (Eukaryotic translation initiation factor 2 subunit beta) (eIF-2-beta) Oryctolagus cuniculus (Rabbit) in utero embryonic development [GO:0001701]; male germ cell proliferation [GO:0002176]; male gonad development [GO:0008584] GO:0001701; GO:0002176; GO:0003743; GO:0005850; GO:0008584; GO:0045202; GO:0046872 31696 XR_006392711.1 0 0 0 7 0 NA NA NA NA NA NA 31697 XM_044329318.1 1 7 2 3 0 NA NA NA NA NA NA 31698 XM_029329976.2 37 0 41 49 119 Q32LL6 2.15e-44 MORN repeat-containing protein 5 Bos taurus (Bovine) NA NA 31699 XM_044314516.1 66 16 0 43 12 NA NA NA NA NA NA 31700 XM_044319946.1 1103 982 699 1086 766 Q9Z136 4.35e-32 Hamartin (Tuberous sclerosis 1 protein homolog) Rattus norvegicus (Rat) activation of GTPase activity [GO:0090630]; adaptive immune response [GO:0002250]; adult locomotory behavior [GO:0008344]; associative learning [GO:0008306]; cardiac muscle cell differentiation [GO:0055007]; cell population proliferation [GO:0008283]; cell projection organization [GO:0030030]; cell-matrix adhesion [GO:0007160]; cellular response to oxygen-glucose deprivation [GO:0090650]; cerebral cortex development [GO:0021987]; glucose import [GO:0046323]; hippocampus development [GO:0021766]; kidney development [GO:0001822]; memory T cell differentiation [GO:0043379]; myelination [GO:0042552]; negative regulation of ATP-dependent activity [GO:0032780]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of macroautophagy [GO:0016242]; negative regulation of neuron projection development [GO:0010977]; negative regulation of oxidative stress-induced neuron death [GO:1903204]; negative regulation of TOR signaling [GO:0032007]; negative regulation of translation [GO:0017148]; nervous system development [GO:0007399]; neural tube closure [GO:0001843]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of macroautophagy [GO:0016239]; positive regulation of stress fiber assembly [GO:0051496]; potassium ion transport [GO:0006813]; protein stabilization [GO:0050821]; regulation of cell cycle [GO:0051726]; regulation of cell-matrix adhesion [GO:0001952]; regulation of focal adhesion assembly [GO:0051893]; regulation of neuron death [GO:1901214]; regulation of phosphoprotein phosphatase activity [GO:0043666]; regulation of protein kinase activity [GO:0045859]; regulation of stress fiber assembly [GO:0051492]; regulation of translation [GO:0006417]; response to insulin [GO:0032868]; response to nutrient levels [GO:0031667]; response to peptide [GO:1901652]; rRNA export from nucleus [GO:0006407]; synapse organization [GO:0050808] GO:0001822; GO:0001843; GO:0001952; GO:0002250; GO:0005634; GO:0005737; GO:0005811; GO:0005829; GO:0005856; GO:0005884; GO:0005938; GO:0006407; GO:0006417; GO:0006813; GO:0007160; GO:0007399; GO:0008283; GO:0008285; GO:0008306; GO:0008344; GO:0010977; GO:0014069; GO:0016020; GO:0016239; GO:0016242; GO:0017148; GO:0021766; GO:0021987; GO:0030027; GO:0030030; GO:0030426; GO:0030544; GO:0031667; GO:0032007; GO:0032780; GO:0032794; GO:0032868; GO:0032991; GO:0033596; GO:0034260; GO:0042030; GO:0042552; GO:0042995; GO:0043231; GO:0043379; GO:0043666; GO:0044877; GO:0045792; GO:0045859; GO:0046323; GO:0047485; GO:0048471; GO:0050808; GO:0050821; GO:0051087; GO:0051492; GO:0051496; GO:0051726; GO:0051879; GO:0051893; GO:0051894; GO:0055007; GO:0090630; GO:0090650; GO:0101031; GO:1901214; GO:1901652; GO:1903204 31701 XM_044319946.1 1103 982 699 1086 766 Q9Z136 4.91e-32 Hamartin (Tuberous sclerosis 1 protein homolog) Rattus norvegicus (Rat) activation of GTPase activity [GO:0090630]; adaptive immune response [GO:0002250]; adult locomotory behavior [GO:0008344]; associative learning [GO:0008306]; cardiac muscle cell differentiation [GO:0055007]; cell population proliferation [GO:0008283]; cell projection organization [GO:0030030]; cell-matrix adhesion [GO:0007160]; cellular response to oxygen-glucose deprivation [GO:0090650]; cerebral cortex development [GO:0021987]; glucose import [GO:0046323]; hippocampus development [GO:0021766]; kidney development [GO:0001822]; memory T cell differentiation [GO:0043379]; myelination [GO:0042552]; negative regulation of ATP-dependent activity [GO:0032780]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of macroautophagy [GO:0016242]; negative regulation of neuron projection development [GO:0010977]; negative regulation of oxidative stress-induced neuron death [GO:1903204]; negative regulation of TOR signaling [GO:0032007]; negative regulation of translation [GO:0017148]; nervous system development [GO:0007399]; neural tube closure [GO:0001843]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of macroautophagy [GO:0016239]; positive regulation of stress fiber assembly [GO:0051496]; potassium ion transport [GO:0006813]; protein stabilization [GO:0050821]; regulation of cell cycle [GO:0051726]; regulation of cell-matrix adhesion [GO:0001952]; regulation of focal adhesion assembly [GO:0051893]; regulation of neuron death [GO:1901214]; regulation of phosphoprotein phosphatase activity [GO:0043666]; regulation of protein kinase activity [GO:0045859]; regulation of stress fiber assembly [GO:0051492]; regulation of translation [GO:0006417]; response to insulin [GO:0032868]; response to nutrient levels [GO:0031667]; response to peptide [GO:1901652]; rRNA export from nucleus [GO:0006407]; synapse organization [GO:0050808] GO:0001822; GO:0001843; GO:0001952; GO:0002250; GO:0005634; GO:0005737; GO:0005811; GO:0005829; GO:0005856; GO:0005884; GO:0005938; GO:0006407; GO:0006417; GO:0006813; GO:0007160; GO:0007399; GO:0008283; GO:0008285; GO:0008306; GO:0008344; GO:0010977; GO:0014069; GO:0016020; GO:0016239; GO:0016242; GO:0017148; GO:0021766; GO:0021987; GO:0030027; GO:0030030; GO:0030426; GO:0030544; GO:0031667; GO:0032007; GO:0032780; GO:0032794; GO:0032868; GO:0032991; GO:0033596; GO:0034260; GO:0042030; GO:0042552; GO:0042995; GO:0043231; GO:0043379; GO:0043666; GO:0044877; GO:0045792; GO:0045859; GO:0046323; GO:0047485; GO:0048471; GO:0050808; GO:0050821; GO:0051087; GO:0051492; GO:0051496; GO:0051726; GO:0051879; GO:0051893; GO:0051894; GO:0055007; GO:0090630; GO:0090650; GO:0101031; GO:1901214; GO:1901652; GO:1903204 31702 XM_029347150.2 0 15 0 3 9 P30974 2.49e-27 Tachykinin-like peptides receptor 86C (NKD) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; inter-male aggressive behavior [GO:0002121]; neuropeptide signaling pathway [GO:0007218]; tachykinin receptor signaling pathway [GO:0007217] GO:0002121; GO:0004995; GO:0005886; GO:0007186; GO:0007217; GO:0007218; GO:0008188; GO:0016020 31703 XM_044311900.1 4 360 176 119 26 NA NA NA NA NA NA 31704 XM_044326211.1 996 427 480 209 1617 NA NA NA NA NA NA 31705 XM_029344565.2 4 5 1 6 9 NA NA NA NA NA NA 31706 XR_006392012.1 12 23 10 16 14 NA NA NA NA NA NA 31707 XM_044329111.1 0 20 93 13 0 NA NA NA NA NA NA 31708 XM_029342534.2 10747 7183 8711 8617 8981 NA NA NA NA NA NA 31709 XM_044326950.1 3 0 0 13 34 NA NA NA NA NA NA 31710 XR_006394155.1 3 2 0 0 16 NA NA NA NA NA NA 31711 XM_029332602.2 40 0 0 37 100 P49337 3.61e-67 Protein Wnt-4 Gallus gallus (Chicken) canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; kidney morphogenesis [GO:0060993]; negative regulation of androgen biosynthetic process [GO:2000180]; neuron differentiation [GO:0030182]; positive regulation of cartilage development [GO:0061036]; positive regulation of skeletal muscle cell proliferation [GO:0014858]; positive regulation of skeletal muscle fiber differentiation [GO:1902811] GO:0005109; GO:0005125; GO:0005615; GO:0005737; GO:0014858; GO:0030182; GO:0045165; GO:0060070; GO:0060993; GO:0061036; GO:1902811; GO:2000180 31712 XM_029340593.2 146 181 181 123 204 Q9CZP0 1.11e-56 Ufm1-specific protease 1 (UfSP1) (EC 3.4.22.-) Mus musculus (Mouse) proteolysis [GO:0006508] GO:0006508; GO:0071567 31713 XM_029347277.2 7413 5017 4959 7721 5949 A5D6U8 2e-166 Acid phosphatase type 7 (EC 3.1.3.2) (Purple acid phosphatase long form) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0003993; GO:0005576; GO:0046872 31714 XM_029334797.2 101 179 180 508 345 G3M4F8 1.08e-45 Octopamine receptor beta-2R (CsOA2B2) Chilo suppressalis (Asiatic rice borer moth) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cellular response to amine stimulus [GO:0071418]; octopamine signaling pathway [GO:0071927]; tyramine signaling pathway [GO:0071928] GO:0004989; GO:0005886; GO:0007189; GO:0008226; GO:0016020; GO:0071418; GO:0071927; GO:0071928 31715 XM_044326394.1 1277 955 699 1287 1773 O97593 0 Structural maintenance of chromosomes protein 1A (SMC protein 1A) (SMC-1A) Bos taurus (Bovine) cell division [GO:0051301]; DNA repair [GO:0006281]; meiotic cell cycle [GO:0051321]; mitotic spindle assembly [GO:0090307]; response to DNA damage checkpoint signaling [GO:0072423]; response to radiation [GO:0009314]; sister chromatid cohesion [GO:0007062]; somatic stem cell population maintenance [GO:0035019] GO:0000776; GO:0003677; GO:0003682; GO:0005524; GO:0005634; GO:0005654; GO:0005829; GO:0006281; GO:0007062; GO:0008278; GO:0009314; GO:0016363; GO:0016887; GO:0030893; GO:0035019; GO:0036033; GO:0046982; GO:0051301; GO:0051321; GO:0072423; GO:0090307; GO:0097431 31716 XM_029330692.2 61 8 27 49 41 Q9D0S4 2.28e-30 Neuralized-like protein 2 Mus musculus (Mouse) intracellular signal transduction [GO:0035556]; myofibril assembly [GO:0030239]; sarcomere organization [GO:0045214] GO:0005927; GO:0030239; GO:0030891; GO:0035556; GO:0045214; GO:0061630 31717 XM_029349421.2 10388 11821 4881 8486 3507 Q6PBJ2 8.22e-138 Cilia- and flagella-associated protein 20 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; positive regulation of cell motility [GO:2000147]; positive regulation of feeding behavior [GO:2000253]; protein polyglutamylation [GO:0018095]; regulation of cilium beat frequency involved in ciliary motility [GO:0060296]; regulation of heart looping [GO:1901207]; regulation of somitogenesis [GO:0014807]; specification of axis polarity [GO:0065001] GO:0005634; GO:0005814; GO:0005879; GO:0005929; GO:0014807; GO:0018095; GO:0031514; GO:0036064; GO:0060271; GO:0060296; GO:0065001; GO:1901207; GO:2000147; GO:2000253 31718 XM_044308031.1 47 53 0 0 64 NA NA NA NA NA NA 31719 XM_029343234.2 1408 1110 1093 2133 1767 O43896 4.55e-76 Kinesin-like protein KIF1C Homo sapiens (Human) anterograde neuronal dense core vesicle transport [GO:1990048]; cytoskeleton-dependent intracellular transport [GO:0030705]; microtubule-based movement [GO:0007018]; retrograde neuronal dense core vesicle transport [GO:1990049]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; vesicle-mediated transport [GO:0016192] GO:0003723; GO:0003774; GO:0003777; GO:0005524; GO:0005783; GO:0005794; GO:0005871; GO:0005874; GO:0006890; GO:0007018; GO:0008017; GO:0008574; GO:0016192; GO:0016887; GO:0030424; GO:0030425; GO:0030705; GO:1904115; GO:1990048; GO:1990049 31720 XM_029327216.2 1360 715 540 1263 0 P47736 2.88e-114 Rap1 GTPase-activating protein 1 (Rap1GAP) (Rap1GAP1) Homo sapiens (Human) activation of GTPase activity [GO:0090630]; adaptive immune response [GO:0002250]; cellular response to glial cell derived neurotrophic factor [GO:1990792]; negative regulation of GTP binding [GO:1904425]; negative regulation of microvillus assembly [GO:1903697]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of thyroid gland epithelial cell proliferation [GO:1904442]; positive regulation of GTPase activity [GO:0043547]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] GO:0000139; GO:0002250; GO:0003924; GO:0005096; GO:0005737; GO:0005769; GO:0005829; GO:0007165; GO:0016020; GO:0030424; GO:0030425; GO:0031267; GO:0042803; GO:0043025; GO:0043087; GO:0043547; GO:0045665; GO:0051056; GO:0090630; GO:1903697; GO:1904425; GO:1904442; GO:1990792 31721 XM_029347250.2 12478 13891 8939 13500 14180 O35920 0 Calpain-9 (EC 3.4.22.-) (Digestive tract-specific calpain) (New calpain 4) (nCL-4) Rattus norvegicus (Rat) proteolysis [GO:0006508] GO:0004198; GO:0005509; GO:0005737; GO:0006508 31722 XR_006391286.1 21 0 22 3 0 NA NA NA NA NA NA 31723 XM_029343016.2 1415 874 938 1846 1552 A0A1D5NSM8 2.13e-31 NA NA NA NA 31724 XM_029343016.2 1415 874 938 1846 1552 A0A1D5NSM8 1.51e-23 NA NA NA NA 31725 XM_029343016.2 1415 874 938 1846 1552 A0A1D5NSM8 6.28e-23 NA NA NA NA 31726 XM_029343016.2 1415 874 938 1846 1552 A0A1D5NSM8 6.35e-21 NA NA NA NA 31727 XM_044325576.1 718 630 336 559 510 NA NA NA NA NA NA 31728 XM_044323321.1 94 81 29 104 67 Q3UNX5 0 Acyl-coenzyme A synthetase ACSM3, mitochondrial (EC 6.2.1.2) (Acyl-CoA synthetase medium-chain family member 3) (Butyrate--CoA ligase 3) (Butyryl-coenzyme A synthetase 3) (Middle-chain acyl-CoA synthetase 3) (Propionate--CoA ligase) (EC 6.2.1.17) (Protein SA homolog) Mus musculus (Mouse) acyl-CoA metabolic process [GO:0006637]; fatty acid biosynthetic process [GO:0006633] GO:0004321; GO:0005524; GO:0005739; GO:0005759; GO:0006633; GO:0006637; GO:0015645; GO:0018729; GO:0043759; GO:0046872; GO:0047760; GO:0050218 31729 XM_044310497.1 0 0 0 0 10 NA NA NA NA NA NA 31730 XM_029332593.2 136 29 26 52 43 Q7RTR2 7.23e-61 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 31731 XM_029332593.2 136 29 26 52 43 Q7RTR2 2.54e-60 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 31732 XM_029332593.2 136 29 26 52 43 Q7RTR2 3.27e-56 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 31733 XM_029332593.2 136 29 26 52 43 Q7RTR2 7.56e-56 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 31734 XM_029332593.2 136 29 26 52 43 Q7RTR2 8.5e-54 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 31735 XM_029347941.2 107 124 25 175 64 NA NA NA NA NA NA 31736 XM_029337884.2 19 81 4 37 90 NA NA NA NA NA NA 31737 XM_044317113.1 37 32 21 30 107 NA NA NA NA NA NA 31738 XM_044308744.1 57 0 3 62 0 NA NA NA NA NA NA 31739 XM_029353617.2 161 73 17 126 58 P32018 2.19e-24 Collagen alpha-1(XIV) chain (Undulin) Gallus gallus (Chicken) cell adhesion [GO:0007155] GO:0005576; GO:0005581; GO:0007155 31740 XM_044308263.1 205 23 73 204 21 P48380 0 Transcription factor RFX3 (Regulatory factor X 3) Homo sapiens (Human) cell maturation [GO:0048469]; cilium assembly [GO:0060271]; cilium-dependent cell motility [GO:0060285]; endocrine pancreas development [GO:0031018]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type B pancreatic cell development [GO:2000078]; regulation of DNA-templated transcription [GO:0006355]; regulation of insulin secretion [GO:0050796]; regulation of transcription by RNA polymerase II [GO:0006357]; type B pancreatic cell maturation [GO:0072560] GO:0000785; GO:0000976; GO:0000978; GO:0000981; GO:0003677; GO:0003700; GO:0005576; GO:0005634; GO:0005667; GO:0006355; GO:0006357; GO:0031018; GO:0045892; GO:0045893; GO:0045944; GO:0048469; GO:0050796; GO:0060271; GO:0060285; GO:0060287; GO:0072560; GO:1990837; GO:2000078 31741 XR_006393295.1 43 54 64 10 82 NA NA NA NA NA NA 31742 XM_044329344.1 56 80 60 149 39 Q9CWG8 3.71e-136 Protein arginine methyltransferase NDUFAF7, mitochondrial (EC 2.1.1.320) (NADH dehydrogenase [ubiquinone] complex I, assembly factor 7) (Protein midA homolog) Mus musculus (Mouse) mitochondrial respiratory chain complex I assembly [GO:0032981]; peptidyl-arginine methylation, to symmetrical-dimethyl arginine [GO:0019918] GO:0005739; GO:0019899; GO:0019918; GO:0032981; GO:0035243 31743 XM_029343379.2 107 42 65 82 60 Q54TR1 2.68e-61 Counting factor associated protein D Dictyostelium discoideum (Social amoeba) immune response [GO:0006955]; negative regulation of asexual reproduction [GO:1903665]; positive regulation of chemorepellent activity [GO:1903669]; protein localization to plasma membrane [GO:0072659]; proteolysis involved in protein catabolic process [GO:0051603]; sorocarp morphogenesis [GO:0031288] GO:0004197; GO:0005576; GO:0005615; GO:0005764; GO:0006955; GO:0031288; GO:0031410; GO:0051603; GO:0072659; GO:1903665; GO:1903669 31744 XM_044329252.1 0 0 0 40 0 NA NA NA NA NA NA 31745 XM_029332837.2 445 354 174 378 616 O14578 0 Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21) Homo sapiens (Human) actomyosin structure organization [GO:0031032]; G2/M transition of mitotic cell cycle [GO:0000086]; generation of neurons [GO:0048699]; Golgi organization [GO:0007030]; liver development [GO:0001889]; mitotic cell cycle [GO:0000278]; mitotic cytokinesis [GO:0000281]; negative regulation of hippo signaling [GO:0035331]; neuron apoptotic process [GO:0051402]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of cytokinesis [GO:0032467]; regulation of actin polymerization or depolymerization [GO:0008064] GO:0000086; GO:0000278; GO:0000281; GO:0001223; GO:0001889; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0005856; GO:0007030; GO:0008064; GO:0016020; GO:0017124; GO:0018107; GO:0019901; GO:0030165; GO:0030291; GO:0030496; GO:0031032; GO:0031985; GO:0032154; GO:0032467; GO:0035331; GO:0043025; GO:0046872; GO:0048699; GO:0051402; GO:0097110; GO:0106310 31746 XM_044310408.1 754 515 489 535 442 Q9QZS6 1.57e-82 Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (3-OST-3B) (Heparan sulfate 3-O-sulfotransferase 3B1) (m3-OST-3B) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; protein sulfation [GO:0006477] GO:0000139; GO:0001658; GO:0005886; GO:0006024; GO:0006477; GO:0008467; GO:0015012; GO:0033872 31747 XM_029345381.2 927 692 406 1199 815 A0A1L8GXY4 0 Cilia- and flagella-associated protein 43 Xenopus laevis (African clawed frog) epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; regulation of cilium beat frequency [GO:0003356] GO:0003351; GO:0003356; GO:0005576; GO:0005737; GO:0005856; GO:0042995 31748 XM_044318959.1 0 75 69 97 0 P39429 3.43e-25 TNF receptor-associated factor 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF2) (RING-type E3 ubiquitin transferase TRAF2) Mus musculus (Mouse) activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; cellular response to nitric oxide [GO:0071732]; interleukin-17-mediated signaling pathway [GO:0097400]; mRNA stabilization [GO:0048255]; negative regulation of apoptotic process [GO:0043066]; negative regulation of glial cell apoptotic process [GO:0034351]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein K63-linked ubiquitination [GO:0070534]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin production [GO:0002637]; regulation of JNK cascade [GO:0046328]; regulation of protein-containing complex assembly [GO:0043254]; signal transduction [GO:0007165]; signal transduction involved in regulation of gene expression [GO:0023019]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000151; GO:0002637; GO:0002726; GO:0002947; GO:0004842; GO:0005164; GO:0005174; GO:0005737; GO:0005829; GO:0005938; GO:0006915; GO:0007165; GO:0007250; GO:0008270; GO:0009898; GO:0012506; GO:0019899; GO:0019901; GO:0019903; GO:0023019; GO:0030163; GO:0030674; GO:0031435; GO:0031625; GO:0031996; GO:0032743; GO:0032991; GO:0033209; GO:0034351; GO:0035631; GO:0042802; GO:0042981; GO:0043066; GO:0043120; GO:0043122; GO:0043123; GO:0043254; GO:0043507; GO:0044877; GO:0045121; GO:0046328; GO:0046330; GO:0046625; GO:0048255; GO:0051091; GO:0051092; GO:0051865; GO:0065003; GO:0070534; GO:0071732; GO:0097057; GO:0097300; GO:0097400; GO:1903265; GO:1903721; GO:1990604; GO:2001238 31749 XM_029343017.2 6 23 82 54 5 P48040 8.66e-28 Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor) Ovis aries (Sheep) NA GO:0005886; GO:0008502 31750 XM_044323711.1 22 10 0 12 11 O02751 4.86e-24 Craniofacial development protein 2 (p97 bucentaur protein) Bos taurus (Bovine) chromatin remodeling [GO:0006338] GO:0003824; GO:0005634; GO:0005737; GO:0006338 31751 XM_029357189.2 236 177 137 197 492 NA NA NA NA NA NA 31752 XR_006393793.1 29 34 56 30 35 NA NA NA NA NA NA 31753 XM_029336227.2 878 505 411 601 466 O96006 1.59e-45 E3 SUMO-protein ligase ZBED1 (EC 2.3.2.-) (DNA replication-related element-binding factor) (Putative Ac-like transposable element) (Zinc finger BED domain-containing protein 1) (dREF homolog) Homo sapiens (Human) negative regulation by host of viral genome replication [GO:0044828]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein autosumoylation [GO:1990466]; protein sumoylation [GO:0016925]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000785; GO:0000978; GO:0000981; GO:0001228; GO:0003712; GO:0003713; GO:0005634; GO:0005654; GO:0005813; GO:0006355; GO:0006357; GO:0016605; GO:0016925; GO:0019789; GO:0031965; GO:0042802; GO:0043565; GO:0044828; GO:0045944; GO:0046872; GO:0046983; GO:0061665; GO:1990466; GO:1990837 31754 XR_006393584.1 69 5 77 26 60 NA NA NA NA NA NA 31755 XR_006397834.1 0 61 34 2 0 NA NA NA NA NA NA 31756 XM_029355547.2 665 557 595 511 815 A4IIW7 1.6e-140 Cyclin-dependent kinase 14 (EC 2.7.11.22) (Cell division protein kinase 14) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell division [GO:0051301]; G2/M transition of mitotic cell cycle [GO:0000086]; protein phosphorylation [GO:0006468]; regulation of canonical Wnt signaling pathway [GO:0060828]; Wnt signaling pathway [GO:0016055] GO:0000086; GO:0000308; GO:0004693; GO:0005524; GO:0005886; GO:0006468; GO:0016055; GO:0051301; GO:0060828; GO:0106310 31757 XR_006396442.1 0 0 16 0 29 NA NA NA NA NA NA 31758 XM_044307436.1 22 7 0 13 46 NA NA NA NA NA NA 31759 XM_044321799.1 96 35 56 108 0 NA NA NA NA NA NA 31760 XM_029356748.2 28 7 550 846 1617 P54797 3.65e-60 Transport and Golgi organization 2 homolog (Ser/Thr-rich protein T10 in DGCR region) Mus musculus (Mouse) Golgi organization [GO:0007030]; protein secretion [GO:0009306] GO:0005737; GO:0005739; GO:0005794; GO:0005829; GO:0007030; GO:0009306 31761 XR_003823816.2 2 0 0 0 11 NA NA NA NA NA NA 31762 XM_044309163.1 0 240 0 0 0 NA NA NA NA NA NA 31763 XM_044324170.1 414 545 82 497 383 Q61091 3.41e-22 Frizzled-8 (Fz-8) (mFz8) Mus musculus (Mouse) angiogenesis [GO:0001525]; canonical Wnt signaling pathway [GO:0060070]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of protein phosphorylation [GO:0001934]; T cell differentiation in thymus [GO:0033077]; Wnt signaling pathway [GO:0016055] GO:0001525; GO:0001934; GO:0004930; GO:0005102; GO:0005576; GO:0005794; GO:0005886; GO:0016020; GO:0016055; GO:0017147; GO:0030165; GO:0031625; GO:0033077; GO:0042813; GO:0043507; GO:0060070; GO:0098992; GO:1990851 31764 XM_029329299.2 1120 1081 926 811 725 NA NA NA NA NA NA 31765 XR_006395260.1 52 8 60 71 56 NA NA NA NA NA NA 31766 XM_044316108.1 9 3 2 60 16 NA NA NA NA NA NA 31767 XM_029325004.2 2972 2081 1129 2159 1482 Q8VHX6 1.61e-123 Filamin-C (FLN-C) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin) Mus musculus (Mouse) actin filament-based process [GO:0030029]; muscle cell development [GO:0055001]; sarcomere organization [GO:0045214] GO:0003779; GO:0005737; GO:0005829; GO:0005886; GO:0008092; GO:0015629; GO:0016528; GO:0030018; GO:0030029; GO:0030506; GO:0042383; GO:0042802; GO:0045214; GO:0051015; GO:0055001 31768 XM_029325004.2 2972 2081 1129 2159 1482 Q8VHX6 2.4e-92 Filamin-C (FLN-C) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin) Mus musculus (Mouse) actin filament-based process [GO:0030029]; muscle cell development [GO:0055001]; sarcomere organization [GO:0045214] GO:0003779; GO:0005737; GO:0005829; GO:0005886; GO:0008092; GO:0015629; GO:0016528; GO:0030018; GO:0030029; GO:0030506; GO:0042383; GO:0042802; GO:0045214; GO:0051015; GO:0055001 31769 XM_029325004.2 2972 2081 1129 2159 1482 Q8VHX6 6.74e-85 Filamin-C (FLN-C) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin) Mus musculus (Mouse) actin filament-based process [GO:0030029]; muscle cell development [GO:0055001]; sarcomere organization [GO:0045214] GO:0003779; GO:0005737; GO:0005829; GO:0005886; GO:0008092; GO:0015629; GO:0016528; GO:0030018; GO:0030029; GO:0030506; GO:0042383; GO:0042802; GO:0045214; GO:0051015; GO:0055001 31770 XM_029325004.2 2972 2081 1129 2159 1482 Q8VHX6 4.44e-76 Filamin-C (FLN-C) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin) Mus musculus (Mouse) actin filament-based process [GO:0030029]; muscle cell development [GO:0055001]; sarcomere organization [GO:0045214] GO:0003779; GO:0005737; GO:0005829; GO:0005886; GO:0008092; GO:0015629; GO:0016528; GO:0030018; GO:0030029; GO:0030506; GO:0042383; GO:0042802; GO:0045214; GO:0051015; GO:0055001 31771 XM_029325004.2 2972 2081 1129 2159 1482 Q8VHX6 3e-73 Filamin-C (FLN-C) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin) Mus musculus (Mouse) actin filament-based process [GO:0030029]; muscle cell development [GO:0055001]; sarcomere organization [GO:0045214] GO:0003779; GO:0005737; GO:0005829; GO:0005886; GO:0008092; GO:0015629; GO:0016528; GO:0030018; GO:0030029; GO:0030506; GO:0042383; GO:0042802; GO:0045214; GO:0051015; GO:0055001 31772 XM_029325004.2 2972 2081 1129 2159 1482 Q8VHX6 2.52e-52 Filamin-C (FLN-C) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin) Mus musculus (Mouse) actin filament-based process [GO:0030029]; muscle cell development [GO:0055001]; sarcomere organization [GO:0045214] GO:0003779; GO:0005737; GO:0005829; GO:0005886; GO:0008092; GO:0015629; GO:0016528; GO:0030018; GO:0030029; GO:0030506; GO:0042383; GO:0042802; GO:0045214; GO:0051015; GO:0055001 31773 XM_029325004.2 2972 2081 1129 2159 1482 Q8VHX6 4.26e-49 Filamin-C (FLN-C) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin) Mus musculus (Mouse) actin filament-based process [GO:0030029]; muscle cell development [GO:0055001]; sarcomere organization [GO:0045214] GO:0003779; GO:0005737; GO:0005829; GO:0005886; GO:0008092; GO:0015629; GO:0016528; GO:0030018; GO:0030029; GO:0030506; GO:0042383; GO:0042802; GO:0045214; GO:0051015; GO:0055001 31774 XM_029325004.2 2972 2081 1129 2159 1482 Q8VHX6 1.42e-39 Filamin-C (FLN-C) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin) Mus musculus (Mouse) actin filament-based process [GO:0030029]; muscle cell development [GO:0055001]; sarcomere organization [GO:0045214] GO:0003779; GO:0005737; GO:0005829; GO:0005886; GO:0008092; GO:0015629; GO:0016528; GO:0030018; GO:0030029; GO:0030506; GO:0042383; GO:0042802; GO:0045214; GO:0051015; GO:0055001 31775 XM_029325004.2 2972 2081 1129 2159 1482 Q8VHX6 2.44e-23 Filamin-C (FLN-C) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin) Mus musculus (Mouse) actin filament-based process [GO:0030029]; muscle cell development [GO:0055001]; sarcomere organization [GO:0045214] GO:0003779; GO:0005737; GO:0005829; GO:0005886; GO:0008092; GO:0015629; GO:0016528; GO:0030018; GO:0030029; GO:0030506; GO:0042383; GO:0042802; GO:0045214; GO:0051015; GO:0055001 31776 XM_029333664.2 331 189 224 248 274 Q6P9Z4 4.68e-43 Protein fem-1 homolog A (FEM1a) (FEM1-alpha) Danio rerio (Zebrafish) (Brachydanio rerio) negative regulation of inflammatory response [GO:0050728]; positive regulation of inflammatory response [GO:0050729]; protein ubiquitination [GO:0016567]; regulation of ubiquitin-protein transferase activity [GO:0051438]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent protein catabolic process via the C-end degron rule pathway [GO:0140627] GO:0000151; GO:0005739; GO:0006511; GO:0016567; GO:0031462; GO:0050728; GO:0050729; GO:0051438; GO:0140627; GO:1990756 31777 XM_029333664.2 331 189 224 248 274 Q6P9Z4 9.3e-34 Protein fem-1 homolog A (FEM1a) (FEM1-alpha) Danio rerio (Zebrafish) (Brachydanio rerio) negative regulation of inflammatory response [GO:0050728]; positive regulation of inflammatory response [GO:0050729]; protein ubiquitination [GO:0016567]; regulation of ubiquitin-protein transferase activity [GO:0051438]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent protein catabolic process via the C-end degron rule pathway [GO:0140627] GO:0000151; GO:0005739; GO:0006511; GO:0016567; GO:0031462; GO:0050728; GO:0050729; GO:0051438; GO:0140627; GO:1990756 31778 XM_029338002.2 40 54 58 0 46 NA NA NA NA NA NA 31779 XM_029348218.2 0 11 3 8 5 Q09575 4e-41 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 31780 XM_044315446.1 1 0 25 140 1 NA NA NA NA NA NA 31781 XM_029352527.2 6 0 41 0 0 Q9P2K3 7.43e-112 REST corepressor 3 Homo sapiens (Human) histone deacetylation [GO:0016575]; negative regulation of DNA-templated transcription [GO:0045892]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000118; GO:0003714; GO:0005654; GO:0005667; GO:0005829; GO:0006357; GO:0016575; GO:0045892 31782 XM_044319056.1 168 81 94 177 35 Q9Y226 3.76e-58 Solute carrier family 22 member 13 (Organic anion transporter 10) (OAT10) (Organic cation transporter-like 3) (ORCTL-3) (ORCTL3) Homo sapiens (Human) NAD biosynthesis via nicotinamide riboside salvage pathway [GO:0034356]; negative regulation of fatty acid metabolic process [GO:0045922]; nicotinate transport [GO:2001142]; positive regulation of T cell mediated cytotoxicity directed against tumor cell target [GO:0002854]; urate transport [GO:0015747] GO:0002854; GO:0005783; GO:0005794; GO:0005886; GO:0015143; GO:0015747; GO:0016324; GO:0034356; GO:0045922; GO:0070062; GO:0090416; GO:2001142 31783 XM_044315537.1 2 4 0 0 32 NA NA NA NA NA NA 31784 XM_044318947.1 18 0 2 0 0 Q5ZKZ9 2.32e-72 Lipase maturation factor 2 Gallus gallus (Chicken) protein maturation [GO:0051604] GO:0005789; GO:0051604 31785 XM_044318947.1 18 0 2 0 0 Q5ZKZ9 2.43e-47 Lipase maturation factor 2 Gallus gallus (Chicken) protein maturation [GO:0051604] GO:0005789; GO:0051604 31786 XM_044318555.1 83 107 45 161 95 Q68F72 2.3e-77 Solute carrier family 15 member 4 Xenopus laevis (African clawed frog) dipeptide import across plasma membrane [GO:0140206]; innate immune response [GO:0045087]; mast cell homeostasis [GO:0033023]; peptidoglycan transport [GO:0015835]; positive regulation of innate immune response [GO:0045089]; positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [GO:0070430]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of toll-like receptor 7 signaling pathway [GO:0034157]; positive regulation of toll-like receptor 8 signaling pathway [GO:0034161]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; protein transport [GO:0015031]; regulation of isotype switching to IgG isotypes [GO:0048302]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424] GO:0005290; GO:0005765; GO:0015031; GO:0015333; GO:0015647; GO:0015835; GO:0031901; GO:0033023; GO:0034157; GO:0034161; GO:0034165; GO:0036020; GO:0045087; GO:0045089; GO:0048302; GO:0070424; GO:0070430; GO:0070434; GO:0071916; GO:0140206 31787 XM_044317748.1 0 403 319 452 487 Q60431 2.02e-34 Caspase-3 (CASP-3) (EC 3.4.22.56) (Apopain) (Cysteine protease CPP32) (CPP-32) (Protein Yama) (SREBP cleavage activity 1) (SCA-1) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12] Mesocricetus auratus (Golden hamster) intracellular signal transduction [GO:0035556]; positive regulation of amyloid-beta formation [GO:1902004]; proteolysis [GO:0006508]; regulation of protein stability [GO:0031647] GO:0004175; GO:0005737; GO:0006508; GO:0031647; GO:0035556; GO:0097153; GO:0097199; GO:0097200; GO:1902004 31788 XM_044314494.1 13 1 3 0 3 NA NA NA NA NA NA 31789 XR_006392103.1 35 64 66 0 0 NA NA NA NA NA NA 31790 XM_029340166.2 120 22 0 0 30 NA NA NA NA NA NA 31791 XM_029340843.2 1132 857 588 1129 1032 Q8TBF4 5.28e-65 Zinc finger CCHC-type and RNA-binding motif-containing protein 1 (U11/U12 small nuclear ribonucleoprotein 31 kDa protein) (U11/U12 snRNP 31 kDa protein) (U11/U12-31K) Homo sapiens (Human) mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380] GO:0000398; GO:0003723; GO:0005654; GO:0005689; GO:0005829; GO:0008270; GO:0008380 31792 XM_029325042.2 0 126 117 202 482 NA NA NA NA NA NA 31793 XM_029339554.2 1297 1227 844 1400 1249 Q9UQ07 8.56e-154 MAPK/MAK/MRK overlapping kinase (EC 2.7.11.22) (MOK protein kinase) (Renal tumor antigen 1) (RAGE-1) Homo sapiens (Human) intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165] GO:0004672; GO:0004674; GO:0004693; GO:0005524; GO:0005634; GO:0005737; GO:0005929; GO:0006468; GO:0007165; GO:0035556; GO:0046872; GO:0097546; GO:0106310 31794 XR_003827624.1 2 7 2 9 4 NA NA NA NA NA NA 31795 XM_044318336.1 87 2 7 32 43 Q09575 3.4e-26 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 31796 XM_029353434.2 0 0 1 0 15 NA NA NA NA NA NA 31797 XM_029333210.2 639 429 367 502 357 A0A1L8GWK2 5.53e-159 NA NA NA NA 31798 XM_044328810.1 149 120 92 85 154 A4FUY7 4.48e-60 Molybdopterin synthase catalytic subunit (EC 2.8.1.12) (Molybdenum cofactor synthesis protein 2 large subunit) (Molybdenum cofactor synthesis protein 2B) (MOCS2B) Bos taurus (Bovine) Mo-molybdopterin cofactor biosynthetic process [GO:0006777] GO:0005829; GO:0006777; GO:0016607; GO:0019008; GO:0030366 31799 XM_044320271.1 1 31 60 10 76 Q8N2E2 2.13e-26 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 31800 XM_044311405.1 56 1 26 8 253 NA NA NA NA NA NA 31801 XR_006396263.1 18 0 10 18 35 NA NA NA NA NA NA 31802 XR_006396665.1 316 166 477 265 1120 NA NA NA NA NA NA 31803 XM_029347965.2 10 0 1 11 35 O15973 6.92e-32 Rhodopsin, GQ-coupled (GQ-rhodopsin) Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis) phototransduction [GO:0007602]; visual perception [GO:0007601] GO:0004930; GO:0005886; GO:0007601; GO:0007602; GO:0009881 31804 XM_044327809.1 2 0 6 0 6 NA NA NA NA NA NA 31805 XM_044320953.1 29 0 21 0 81 NA NA NA NA NA NA 31806 XM_044323706.1 8 3 0 2 36 NA NA NA NA NA NA 31807 XM_044309959.1 43 39 2 24 27 Q96AY4 5.28e-104 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31808 XM_044309959.1 43 39 2 24 27 Q96AY4 3.18e-99 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31809 XM_044309959.1 43 39 2 24 27 Q96AY4 7.19e-96 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31810 XM_044309959.1 43 39 2 24 27 Q96AY4 7.96e-94 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31811 XM_044309959.1 43 39 2 24 27 Q96AY4 8.64e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31812 XM_044309959.1 43 39 2 24 27 Q96AY4 4.58e-89 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31813 XM_044309959.1 43 39 2 24 27 Q96AY4 5.53e-88 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31814 XM_044309959.1 43 39 2 24 27 Q96AY4 1.96e-86 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31815 XM_044309959.1 43 39 2 24 27 Q96AY4 8.34e-58 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31816 XM_044309959.1 43 39 2 24 27 Q96AY4 1.66e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31817 XM_029344118.2 5293 3906 2191 3516 2805 Q8VHT6 4.84e-104 Arsenite methyltransferase (EC 2.1.1.137) (Methylarsonite methyltransferase) (S-adenosyl-L-methionine:arsenic(III) methyltransferase) Rattus norvegicus (Rat) arsonoacetate metabolic process [GO:0018872]; methylation [GO:0032259]; response to arsenic-containing substance [GO:0046685]; toxin metabolic process [GO:0009404] GO:0005829; GO:0008168; GO:0008276; GO:0008757; GO:0009404; GO:0018872; GO:0030791; GO:0030792; GO:0032259; GO:0046685 31818 XM_029326064.2 0 0 0 0 27 NA NA NA NA NA NA 31819 XM_029340520.2 1435 989 829 1477 1536 O75165 0 DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8) Homo sapiens (Human) endosome organization [GO:0007032]; osteoblast differentiation [GO:0001649]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of early endosome to recycling endosome transport [GO:1902954] GO:0001649; GO:0005765; GO:0005829; GO:0005886; GO:0006898; GO:0007032; GO:0010008; GO:0015031; GO:0016020; GO:0030667; GO:0031901; GO:0035577; GO:0043231; GO:0070062; GO:1902954; GO:2000641 31820 XM_029327242.2 51 0 0 44 30 NA NA NA NA NA NA 31821 XR_003827979.2 109 9 0 65 100 NA NA NA NA NA NA 31822 XM_029332767.2 5567 5531 3604 4709 5869 P84023 0 Mothers against decapentaplegic homolog 3 (MAD homolog 3) (Mad3) (Mothers against DPP homolog 3) (SMAD family member 3) (SMAD 3) (Smad3) Gallus gallus (Chicken) activin receptor signaling pathway [GO:0032924]; anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; positive regulation of transcription by RNA polymerase II [GO:0045944]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0000978; GO:0000981; GO:0000987; GO:0003700; GO:0005634; GO:0005667; GO:0005737; GO:0007179; GO:0009653; GO:0030154; GO:0032924; GO:0045944; GO:0046872; GO:0060395; GO:0070411; GO:0071141; GO:0071144 31823 XM_029350022.2 375 175 143 308 213 O75808 0 Calpain-15 (EC 3.4.22.-) (Small optic lobes homolog) Homo sapiens (Human) proteolysis [GO:0006508] GO:0004198; GO:0005737; GO:0006508; GO:0046872 31824 XM_044307115.1 11 2 0 0 137 Q9U6Y6 4.17e-112 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 31825 XM_029331718.2 584 561 363 493 616 Q5T1B0 3.05e-143 Axonemal dynein light chain domain-containing protein 1 Homo sapiens (Human) NA NA 31826 XM_029356075.2 570 474 500 942 585 Q9CZV8 4.11e-28 F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like) Mus musculus (Mouse) behavioral fear response [GO:0001662]; regulation of protein catabolic process at presynapse, modulating synaptic transmission [GO:0099575]; regulation of synaptic vesicle exocytosis [GO:2000300]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0001662; GO:0005737; GO:0019005; GO:0031146; GO:0045202; GO:0098685; GO:0098793; GO:0098978; GO:0099575; GO:2000300 31827 XR_006394249.1 48 4 25 21 41 NA NA NA NA NA NA 31828 XM_029332678.2 146 167 278 130 206 Q9H4G4 2.96e-28 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Homo sapiens (Human) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070062; GO:0070374 31829 XM_029336994.2 15 11 24 153 65 Q9BVG8 1.99e-149 Kinesin-like protein KIFC3 Homo sapiens (Human) epithelial cell-cell adhesion [GO:0090136]; Golgi organization [GO:0007030]; microtubule-based movement [GO:0007018]; microtubule-based process [GO:0007017]; visual perception [GO:0007601]; zonula adherens maintenance [GO:0045218] GO:0003777; GO:0005524; GO:0005794; GO:0005813; GO:0005871; GO:0005874; GO:0005915; GO:0007017; GO:0007018; GO:0007030; GO:0007601; GO:0008017; GO:0015630; GO:0030659; GO:0042802; GO:0045218; GO:0070062; GO:0090136 31830 XM_044328438.1 37 18 14 74 20 NA NA NA NA NA NA 31831 XM_044326381.1 42 17 4 32 51 NA NA NA NA NA NA 31832 XM_029327312.2 73 22 54 73 172 NA NA NA NA NA NA 31833 XM_044315489.1 0 0 0 0 8 NA NA NA NA NA NA 31834 XM_029339990.2 343 181 181 251 285 Q5ZL00 0 ER membrane protein complex subunit 1 Gallus gallus (Chicken) protein insertion into ER membrane by stop-transfer membrane-anchor sequence [GO:0045050]; tail-anchored membrane protein insertion into ER membrane [GO:0071816] GO:0005789; GO:0016020; GO:0045050; GO:0071816; GO:0072546 31835 XM_029342660.2 369 221 73 283 341 NA NA NA NA NA NA 31836 XM_044327828.1 78 5 13 26 53 NA NA NA NA NA NA 31837 XM_029353526.2 513 331 317 322 584 NA NA NA NA NA NA 31838 XR_003828452.2 32 39 0 22 0 NA NA NA NA NA NA 31839 XM_044323565.1 483 56 122 236 721 Q96DM1 8.28e-33 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 31840 XM_029330922.2 2086 1535 734 756 852 Q5XIR8 1.16e-47 Clathrin heavy chain linker domain-containing protein 1 Rattus norvegicus (Rat) NA NA 31841 XM_029335609.2 1529 1199 889 1336 1362 Q2KIR8 5.06e-137 L-threonine 3-dehydrogenase, mitochondrial (EC 1.1.1.103) Bos taurus (Bovine) L-threonine catabolic process to glycine [GO:0019518]; threonine catabolic process [GO:0006567] GO:0005739; GO:0006567; GO:0008743; GO:0019518; GO:0042802 31842 XM_044324687.1 105 12 123 70 306 O43422 5.62e-24 52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (Death-associated protein 4) (THAP domain-containing protein 0) (THAP domain-containing protein 12) Homo sapiens (Human) negative regulation of cell population proliferation [GO:0008285]; signal transduction [GO:0007165] GO:0003677; GO:0005634; GO:0007165; GO:0008285; GO:0046872; GO:0046983 31843 XM_044321880.1 242 419 242 174 281 H9XP47 4.03e-40 NA NA NA NA 31844 XM_029346347.2 16 28 26 23 5 NA NA NA NA NA NA 31845 XM_029332351.2 108 207 25 104 54 Q9NXG6 1.19e-63 Transmembrane prolyl 4-hydroxylase (P4H-TM) (EC 1.14.11.29) (Hypoxia-inducible factor prolyl hydroxylase 4) (HIF-PH4) (HIF-prolyl hydroxylase 4) (HPH-4) Homo sapiens (Human) peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; regulation of erythrocyte differentiation [GO:0045646] GO:0004656; GO:0005506; GO:0005509; GO:0005783; GO:0005789; GO:0016706; GO:0018401; GO:0031418; GO:0045646 31846 XM_029333327.2 1929 2144 1358 1640 1388 Q86V85 1.02e-67 Integral membrane protein GPR180 (Intimal thickness-related receptor) Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186]; response to pheromone [GO:0019236] GO:0007186; GO:0016020; GO:0019236 31847 XM_044310152.1 0 0 2 79 0 NA NA NA NA NA NA 31848 XM_044326306.1 105 166 159 225 100 Q9DC53 0 Copine-8 (Copine VIII) Mus musculus (Mouse) cellular response to calcium ion [GO:0071277] GO:0005544; GO:0005886; GO:0046872; GO:0071277 31849 XM_044316730.1 27 35 14 35 11 P41041 5.76e-33 Calmodulin (CaM) Pneumocystis carinii NA GO:0005509 31850 XM_029332492.2 0 325 914 475 1221 Q4R562 1.61e-153 Beta-arrestin-1 (Arrestin beta-1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) negative regulation of Notch signaling pathway [GO:0045746]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; protein transport [GO:0015031]; signal transduction [GO:0007165]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0001934; GO:0002092; GO:0005634; GO:0005905; GO:0006511; GO:0007165; GO:0015031; GO:0031143; GO:0031410; GO:0045746 31851 XM_029325887.2 0 43 204 97 90 NA NA NA NA NA NA 31852 XR_006395686.1 0 118 21 4 0 Q28C69 1.85e-76 Enolase-phosphatase E1 (EC 3.1.3.77) (2,3-diketo-5-methylthio-1-phosphopentane phosphatase) (MASA homolog) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284] GO:0000287; GO:0005634; GO:0005737; GO:0019284; GO:0019509; GO:0043715; GO:0043716; GO:0043874 31853 XR_003825326.2 10 11 21 22 36 NA NA NA NA NA NA 31854 XM_044322960.1 139 32 35 38 112 NA NA NA NA NA NA 31855 XM_029342812.2 468 259 576 140 177 NA NA NA NA NA NA 31856 XM_029356982.2 102 3 78 137 107 Q6QNK2 2.06e-72 Adhesion G-protein coupled receptor D1 (G-protein coupled receptor 133) (G-protein coupled receptor PGR25) Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0005654; GO:0005886; GO:0007166; GO:0007186; GO:0007189; GO:0016020 31857 XM_044327467.1 64 12 13 113 68 Q7RTR2 6.59e-34 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 31858 XM_044327467.1 64 12 13 113 68 Q7RTR2 6.91e-30 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 31859 XM_044327467.1 64 12 13 113 68 Q7RTR2 2.47e-27 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 31860 XM_029343318.2 456 505 229 382 351 NA NA NA NA NA NA 31861 XM_029345383.2 156 0 58 0 94 Q5ZKJ5 2.38e-101 Transmembrane protein 180 (Major facilitator superfamily domain-containing 13A) Gallus gallus (Chicken) NA GO:0016020 31862 XM_029345383.2 156 0 58 0 94 Q5ZKJ5 2.46e-53 Transmembrane protein 180 (Major facilitator superfamily domain-containing 13A) Gallus gallus (Chicken) NA GO:0016020 31863 XM_044314592.1 0 0 0 0 16 NA NA NA NA NA NA 31864 XR_006394615.1 65 53 76 28 124 NA NA NA NA NA NA 31865 XM_029346658.2 545 215 245 238 318 NA NA NA NA NA NA 31866 XM_044325830.1 3 8 47 11 51 NA NA NA NA NA NA 31867 XM_044318790.1 18 0 7 5 188 NA NA NA NA NA NA 31868 XM_044326440.1 22 124 104 110 26 NA NA NA NA NA NA 31869 XM_029327337.2 87 40 5 68 54 NA NA NA NA NA NA 31870 XM_044311939.1 184 42 197 69 514 NA NA NA NA NA NA 31871 XM_029333323.2 369 201 92 140 128 A0JPI9 1.27e-64 Leucine-rich repeat-containing protein 74A (Leucine-rich repeat-containing protein 74) Rattus norvegicus (Rat) NA NA 31872 XR_006392757.1 0 0 0 26 46 P04323 1.04e-61 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 31873 XM_029356918.2 1024 685 811 1353 840 Q5R839 1.12e-152 Solute carrier family 41 member 1 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cellular magnesium ion homeostasis [GO:0010961]; cellular response to magnesium ion [GO:0071286] GO:0010961; GO:0015095; GO:0016323; GO:0032991; GO:0061768; GO:0071286 31874 XM_029357406.2 5 10 11 9 42 NA NA NA NA NA NA 31875 XM_044322879.1 959 1300 853 938 4023 P15882 2.71e-172 N-chimaerin (A-chimaerin) (Alpha-chimerin) (N-chimerin) (NC) (Rho GTPase-activating protein 2) Homo sapiens (Human) ephrin receptor signaling pathway [GO:0048013]; motor neuron axon guidance [GO:0008045]; positive regulation of GTPase activity [GO:0043547]; regulation of axonogenesis [GO:0050770]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056] GO:0005096; GO:0005829; GO:0008045; GO:0043087; GO:0043547; GO:0046872; GO:0046875; GO:0048013; GO:0050770; GO:0051056 31876 XM_029339561.2 168 0 0 19 0 Q17RD7 2.68e-75 Synaptotagmin-16 (Chr14Syt) (Synaptotagmin 14-like protein) (Synaptotagmin XIV-related protein) Homo sapiens (Human) NA GO:0005543; GO:0042802 31877 XM_029355424.2 352 103 236 839 351 Q8CHL0 2.52e-53 Frizzled-5 (Fz-5) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; anterior/posterior axis specification, embryo [GO:0008595]; apoptotic process involved in morphogenesis [GO:0060561]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; canonical Wnt signaling pathway [GO:0060070]; cell maturation [GO:0048469]; cellular response to molecule of bacterial origin [GO:0071219]; chorionic trophoblast cell differentiation [GO:0060718]; embryonic axis specification [GO:0000578]; embryonic camera-type eye development [GO:0031076]; embryonic camera-type eye morphogenesis [GO:0048596]; glandular epithelial cell maturation [GO:0002071]; intestinal epithelial cell maturation [GO:0060574]; labyrinthine layer blood vessel development [GO:0060716]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type II interferon production [GO:0032729]; post-embryonic camera-type eye development [GO:0031077]; presynapse assembly [GO:0099054]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of chorionic trophoblast cell proliferation [GO:1901382]; Spemann organizer formation [GO:0060061]; syncytiotrophoblast cell differentiation involved in labyrinthine layer development [GO:0060715]; T cell differentiation in thymus [GO:0033077]; vasculature development [GO:0001944]; Wnt signaling pathway [GO:0016055] GO:0000139; GO:0000578; GO:0001525; GO:0001540; GO:0001944; GO:0002071; GO:0002726; GO:0004930; GO:0005794; GO:0005886; GO:0005923; GO:0008285; GO:0008289; GO:0008595; GO:0009986; GO:0016020; GO:0016055; GO:0017147; GO:0019901; GO:0030424; GO:0030425; GO:0031076; GO:0031077; GO:0031625; GO:0032729; GO:0032731; GO:0032760; GO:0033077; GO:0042813; GO:0043204; GO:0043507; GO:0044877; GO:0045202; GO:0045944; GO:0048469; GO:0048471; GO:0048596; GO:0060061; GO:0060070; GO:0060561; GO:0060574; GO:0060670; GO:0060715; GO:0060716; GO:0060718; GO:0071219; GO:0098978; GO:0099054; GO:1901382; GO:2000810 31878 XM_044328091.1 4 0 0 3 12 Q9D1A2 0 Cytosolic non-specific dipeptidase (EC 3.4.13.18) (CNDP dipeptidase 2) (Glutamate carboxypeptidase-like protein 1) (Threonyl dipeptidase) Mus musculus (Mouse) proteolysis [GO:0006508] GO:0004180; GO:0005654; GO:0005829; GO:0006508; GO:0008233; GO:0016805; GO:0046872; GO:0070573; GO:0103046 31879 XM_044323202.1 25 0 14 4 2 NA NA NA NA NA NA 31880 XM_029329628.2 31 328 15 595 23 NA NA NA NA NA NA 31881 XM_029350158.2 450 276 217 361 267 A7S6A1 0 FHIP family protein v1g243165 Nematostella vectensis (Starlet sea anemone) NA NA 31882 XR_006392728.1 453 298 221 145 208 NA NA NA NA NA NA 31883 XM_029330893.2 5 26 17 7 14 R1CW23 4.05e-99 Dimethylsulfonioproprionate lyase 7 (DMSP lyase 7) (EC 4.4.1.3) (Dimethylpropiothetin dethiomethylase 7) Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi) NA GO:0047869 31884 XM_029335255.2 912 519 423 493 592 Q9CWL8 0 Beta-catenin-like protein 1 (Nuclear-associated protein) (NAP) Mus musculus (Mouse) adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of apoptotic process [GO:0043065]; somatic diversification of immunoglobulins [GO:0016445] GO:0000398; GO:0000974; GO:0002250; GO:0005634; GO:0005654; GO:0005681; GO:0005813; GO:0005829; GO:0006915; GO:0016445; GO:0019899; GO:0043065 31885 XM_044311897.1 351 145 8 189 222 Q8IZH2 1.48e-41 5'-3' exoribonuclease 1 (EC 3.1.13.-) (Strand-exchange protein 1 homolog) Homo sapiens (Human) cellular response to cycloheximide [GO:0071409]; cellular response to puromycin [GO:1905795]; histone mRNA catabolic process [GO:0071044]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of translation [GO:0017148]; nuclear mRNA surveillance [GO:0071028]; nuclear-transcribed mRNA catabolic process [GO:0000956]; response to testosterone [GO:0033574]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; rRNA catabolic process [GO:0016075] GO:0000932; GO:0000956; GO:0002151; GO:0003723; GO:0004534; GO:0005634; GO:0005829; GO:0005886; GO:0016020; GO:0016075; GO:0017148; GO:0030425; GO:0032211; GO:0033574; GO:0043025; GO:0045202; GO:0051880; GO:0070034; GO:0071028; GO:0071044; GO:0071409; GO:0090503; GO:1905795 31886 XM_044311897.1 351 145 8 189 222 Q8IZH2 2.23e-35 5'-3' exoribonuclease 1 (EC 3.1.13.-) (Strand-exchange protein 1 homolog) Homo sapiens (Human) cellular response to cycloheximide [GO:0071409]; cellular response to puromycin [GO:1905795]; histone mRNA catabolic process [GO:0071044]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of translation [GO:0017148]; nuclear mRNA surveillance [GO:0071028]; nuclear-transcribed mRNA catabolic process [GO:0000956]; response to testosterone [GO:0033574]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; rRNA catabolic process [GO:0016075] GO:0000932; GO:0000956; GO:0002151; GO:0003723; GO:0004534; GO:0005634; GO:0005829; GO:0005886; GO:0016020; GO:0016075; GO:0017148; GO:0030425; GO:0032211; GO:0033574; GO:0043025; GO:0045202; GO:0051880; GO:0070034; GO:0071028; GO:0071044; GO:0071409; GO:0090503; GO:1905795 31887 XM_044324807.1 1029 1429 816 1661 1401 Q6GQB9 0 ER degradation-enhancing alpha-mannosidase-like protein 3 (EC 3.2.1.113) (Alpha-1,2-mannosidase EDEM3) Xenopus laevis (African clawed frog) carbohydrate metabolic process [GO:0005975]; endoplasmic reticulum mannose trimming [GO:1904380]; mannose trimming involved in glycoprotein ERAD pathway [GO:1904382]; protein glycosylation [GO:0006486]; response to unfolded protein [GO:0006986] GO:0004571; GO:0005509; GO:0005788; GO:0005975; GO:0006486; GO:0006986; GO:0016020; GO:0044322; GO:1904380; GO:1904382 31888 XM_029357431.2 43 0 66 405 303 A7MBF6 1.58e-120 Armadillo-like helical domain containing protein 1 Bos taurus (Bovine) NA NA 31889 XM_029341897.2 510 413 215 491 214 A0A1L8G016 4.84e-154 Dynein axonemal assembly factor 11 (DNAAF11) (Leucine-rich repeat-containing protein 6) (Protein tilB homolog) Xenopus laevis (African clawed frog) axonemal dynein complex assembly [GO:0070286]; cerebrospinal fluid circulation [GO:0090660]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; outer dynein arm assembly [GO:0036158]; protein localization to cilium [GO:0061512]; protein localization to motile cilium [GO:0120229] GO:0003351; GO:0005576; GO:0005829; GO:0030317; GO:0031514; GO:0036158; GO:0051649; GO:0060287; GO:0061512; GO:0070286; GO:0090660; GO:0120229; GO:0120293 31890 XM_029349079.2 16048 20083 11418 16279 14215 NA NA NA NA NA NA 31891 XM_029323735.2 2335 2176 601 758 1641 Q5R7L8 5.11e-42 Biogenesis of lysosome-related organelles complex 1 subunit 1 (BLOC-1 subunit 1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) aerobic respiration [GO:0009060]; anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; lysosome localization [GO:0032418]; neuron projection development [GO:0031175]; peptidyl-lysine acetylation [GO:0018394] GO:0005758; GO:0005759; GO:0005765; GO:0005769; GO:0005829; GO:0008089; GO:0009060; GO:0018394; GO:0031083; GO:0031175; GO:0032418; GO:0048490; GO:0099078; GO:1904115 31892 XM_044327087.1 1410 1153 897 3081 2970 P35555 3.12e-61 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 31893 XM_044327087.1 1410 1153 897 3081 2970 P35555 3.26e-58 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 31894 XM_044327087.1 1410 1153 897 3081 2970 P35555 1.33e-49 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 31895 XM_044327087.1 1410 1153 897 3081 2970 P35555 2.06e-45 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 31896 XM_044327087.1 1410 1153 897 3081 2970 P35555 3.37e-45 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 31897 XM_044327087.1 1410 1153 897 3081 2970 P35555 1.25e-44 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 31898 XM_044327087.1 1410 1153 897 3081 2970 P35555 1.54e-44 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 31899 XM_044327087.1 1410 1153 897 3081 2970 P35555 3.41e-44 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 31900 XM_044327087.1 1410 1153 897 3081 2970 P35555 2.21e-40 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 31901 XM_044327087.1 1410 1153 897 3081 2970 P35555 4.93e-38 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 31902 XM_044327087.1 1410 1153 897 3081 2970 P35555 5.55e-32 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 31903 XM_044327087.1 1410 1153 897 3081 2970 P35555 7.05e-32 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 31904 XM_044327087.1 1410 1153 897 3081 2970 P35555 1.74e-31 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 31905 XM_044327087.1 1410 1153 897 3081 2970 P35555 3.32e-31 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 31906 XM_044327087.1 1410 1153 897 3081 2970 P35555 3.41e-31 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 31907 XM_044327087.1 1410 1153 897 3081 2970 P35555 9.01e-28 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 31908 XM_029343184.2 495 0 390 590 352 NA NA NA NA NA NA 31909 XM_044316738.1 0 0 0 27 0 NA NA NA NA NA NA 31910 XM_044320108.1 9 0 0 23 0 Q5U243 2.83e-140 CAP-Gly domain-containing linker protein 3 (Cytoplasmic linker protein 170-related 59 kDa protein) (CLIP-170-related 59 kDa protein) (CLIPR-59) Xenopus laevis (African clawed frog) NA GO:0005795 31911 XM_029350870.2 0 8 31 0 0 NA NA NA NA NA NA 31912 XM_044320745.1 23 7 5 64 42 NA NA NA NA NA NA 31913 XM_029340507.2 112 132 85 46 247 Q5XIN7 2.54e-173 Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGnT1) (EC 2.4.1.-) Rattus norvegicus (Rat) O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493] GO:0000139; GO:0006493; GO:0008375; GO:0016020; GO:0016266; GO:0030145; GO:0047223 31914 XM_029327086.2 266 0 0 53 0 NA NA NA NA NA NA 31915 XR_006394404.1 4 101 51 9 55 NA NA NA NA NA NA 31916 XM_029330054.2 74 26 0 0 21 Q16445 1.12e-69 Gamma-aminobutyric acid receptor subunit alpha-6 (GABA(A) receptor subunit alpha-6) Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid signaling pathway [GO:0007214]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; regulation of postsynaptic membrane potential [GO:0060078]; signal transduction [GO:0007165]; synaptic transmission, GABAergic [GO:0051932] GO:0004890; GO:0005231; GO:0005237; GO:0005886; GO:0007165; GO:0007214; GO:0007268; GO:0008503; GO:0022851; GO:0030594; GO:0032590; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051932; GO:0060078; GO:0098794; GO:0099192; GO:1902476; GO:1902711; GO:1904315 31917 XM_029346184.2 51 107 70 59 66 NA NA NA NA NA NA 31918 XM_044316158.1 16 0 0 0 0 NA NA NA NA NA NA 31919 XM_029352594.2 27 16 23 22 17 NA NA NA NA NA NA 31920 XR_006392777.1 0 7 14 0 21 NA NA NA NA NA NA 31921 XM_029349457.2 42 30 35 3 16 NA NA NA NA NA NA 31922 XM_044309295.1 6 18 23 12 40 NA NA NA NA NA NA 31923 XR_006395909.1 2 32 1 48 63 Q95LU3 5.16e-65 Fibrinogen C domain-containing protein 1 Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0008061; GO:0016020; GO:0046872 31924 XM_044308776.1 0 61 39 211 486 Q6XP49 5.65e-74 Zinc finger protein GLIS3 (GLI-similar 3) Mus musculus (Mouse) negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366] GO:0000122; GO:0000977; GO:0000978; GO:0000981; GO:0001227; GO:0001228; GO:0003677; GO:0003700; GO:0005634; GO:0006357; GO:0006366; GO:0045944; GO:0046872 31925 XM_044317839.1 0 0 11 11 30 NA NA NA NA NA NA 31926 XM_029341717.2 61 903 0 1432 1528 Q96MU7 1.1e-62 YTH domain-containing protein 1 (Splicing factor YT521) (YT521-B) Homo sapiens (Human) dosage compensation by inactivation of X chromosome [GO:0009048]; in utero embryonic development [GO:0001701]; mRNA alternative polyadenylation [GO:0110104]; mRNA export from nucleus [GO:0006406]; mRNA splice site selection [GO:0006376]; mRNA splicing, via spliceosome [GO:0000398]; post-transcriptional regulation of gene expression [GO:0010608]; primary follicle stage [GO:0048160]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of mRNA splicing, via spliceosome [GO:0048024]; spermatogenesis [GO:0007283] GO:0000381; GO:0000398; GO:0001701; GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0005886; GO:0006376; GO:0006406; GO:0007283; GO:0009048; GO:0010608; GO:0016607; GO:0048024; GO:0048160; GO:0110104; GO:1990247 31927 XM_044322324.1 0 0 0 0 105 NA NA NA NA NA NA 31928 XM_044311782.1 28 68 15 71 64 NA NA NA NA NA NA 31929 XM_044323847.1 36 19 20 34 55 P70490 2.83e-24 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 31930 XM_044320410.1 347 203 34 175 139 NA NA NA NA NA NA 31931 XM_044327689.1 0 0 0 15 0 NA NA NA NA NA NA 31932 XR_003825595.2 0 12 0 0 0 NA NA NA NA NA NA 31933 XM_044327884.1 18 49 42 66 0 Q05AL1 0 Armadillo repeat-containing protein 8 Danio rerio (Zebrafish) (Brachydanio rerio) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] GO:0000151; GO:0005634; GO:0005737; GO:0034657; GO:0043161 31934 XM_044328281.1 29 54 41 0 91 NA NA NA NA NA NA 31935 XM_029341076.2 742 473 197 547 254 Q9BZ19 4.59e-39 Ankyrin repeat domain-containing protein 60 Homo sapiens (Human) NA NA 31936 XR_003826719.2 51 1 55 8 132 NA NA NA NA NA NA 31937 XM_044313365.1 169 0 0 0 0 NA NA NA NA NA NA 31938 XR_003827430.2 1 0 7 0 0 NA NA NA NA NA NA 31939 XM_044327631.1 903 589 848 800 347 NA NA NA NA NA NA 31940 XR_006395075.1 12 0 0 10 0 NA NA NA NA NA NA 31941 XM_029341355.2 379 408 174 737 379 A7SGF0 5.94e-51 BLOC-1-related complex subunit 8 homolog Nematostella vectensis (Starlet sea anemone) NA GO:0005765; GO:0099078 31942 XM_044326974.1 9 10 0 18 15 Q80VN0 2.54e-40 Cilia- and flagella-associated protein 100 (Coiled-coil domain-containing protein 37) Mus musculus (Mouse) cilium movement [GO:0003341]; inner dynein arm assembly [GO:0036159] GO:0003341; GO:0031514; GO:0036064; GO:0036159; GO:0070840; GO:0097545 31943 XM_044322688.1 2281 1605 1189 1894 1523 Q7TMK9 9.94e-150 Heterogeneous nuclear ribonucleoprotein Q (hnRNP Q) (Glycine- and tyrosine-rich RNA-binding protein) (GRY-RBP) (NS1-associated protein 1) (Synaptotagmin-binding, cytoplasmic RNA-interacting protein) (pp68) Mus musculus (Mouse) cellular response to type II interferon [GO:0071346]; CRD-mediated mRNA stabilization [GO:0070934]; mRNA modification [GO:0016556]; mRNA processing [GO:0006397]; negative regulation of mRNA modification [GO:0090367]; negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900152]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; negative regulation of translation [GO:0017148]; positive regulation of cytoplasmic translation [GO:2000767]; positive regulation of DNA demethylation [GO:1901537]; positive regulation of translation [GO:0045727]; RNA splicing [GO:0008380] GO:0003723; GO:0003729; GO:0003730; GO:0005634; GO:0005654; GO:0005737; GO:0005783; GO:0005829; GO:0006397; GO:0008143; GO:0008380; GO:0016020; GO:0016556; GO:0017148; GO:0043025; GO:0045293; GO:0045727; GO:0048027; GO:0070934; GO:0070937; GO:0071013; GO:0071204; GO:0071346; GO:0090367; GO:0097452; GO:0106002; GO:1900152; GO:1901537; GO:1990635; GO:1990904; GO:2000623; GO:2000767 31944 XM_044322688.1 2281 1605 1189 1894 1523 Q7TMK9 6.39e-136 Heterogeneous nuclear ribonucleoprotein Q (hnRNP Q) (Glycine- and tyrosine-rich RNA-binding protein) (GRY-RBP) (NS1-associated protein 1) (Synaptotagmin-binding, cytoplasmic RNA-interacting protein) (pp68) Mus musculus (Mouse) cellular response to type II interferon [GO:0071346]; CRD-mediated mRNA stabilization [GO:0070934]; mRNA modification [GO:0016556]; mRNA processing [GO:0006397]; negative regulation of mRNA modification [GO:0090367]; negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900152]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; negative regulation of translation [GO:0017148]; positive regulation of cytoplasmic translation [GO:2000767]; positive regulation of DNA demethylation [GO:1901537]; positive regulation of translation [GO:0045727]; RNA splicing [GO:0008380] GO:0003723; GO:0003729; GO:0003730; GO:0005634; GO:0005654; GO:0005737; GO:0005783; GO:0005829; GO:0006397; GO:0008143; GO:0008380; GO:0016020; GO:0016556; GO:0017148; GO:0043025; GO:0045293; GO:0045727; GO:0048027; GO:0070934; GO:0070937; GO:0071013; GO:0071204; GO:0071346; GO:0090367; GO:0097452; GO:0106002; GO:1900152; GO:1901537; GO:1990635; GO:1990904; GO:2000623; GO:2000767 31945 XM_029329888.2 38 0 0 0 0 NA NA NA NA NA NA 31946 XM_044327996.1 738 725 436 650 589 Q3S8M4 1.43e-95 Elongation of very long chain fatty acids protein 4 (EC 2.3.1.199) (3-keto acyl-CoA synthase ELOVL4) (ELOVL fatty acid elongase 4) (ELOVL FA elongase 4) (Very long chain 3-ketoacyl-CoA synthase 4) (Very long chain 3-oxoacyl-CoA synthase 4) Macaca mulatta (Rhesus macaque) fatty acid elongation, monounsaturated fatty acid [GO:0034625]; fatty acid elongation, polyunsaturated fatty acid [GO:0034626]; fatty acid elongation, saturated fatty acid [GO:0019367]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; sphingolipid biosynthetic process [GO:0030148]; unsaturated fatty acid biosynthetic process [GO:0006636]; very long-chain fatty acid biosynthetic process [GO:0042761] GO:0005783; GO:0005789; GO:0006636; GO:0009922; GO:0019367; GO:0030148; GO:0034625; GO:0034626; GO:0035338; GO:0042761; GO:0102756 31947 XM_044316127.1 4 10 0 18 10 Q8NDA2 1.92e-26 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 31948 XM_044316127.1 4 10 0 18 10 Q8NDA2 4.59e-25 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 31949 XM_044316127.1 4 10 0 18 10 Q8NDA2 1.59e-23 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 31950 XM_044316127.1 4 10 0 18 10 Q8NDA2 1.91e-21 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 31951 XM_044317152.1 82 14 21 54 35 Q149M9 8.3e-121 NACHT domain- and WD repeat-containing protein 1 Homo sapiens (Human) negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of gene expression [GO:0010628] GO:0005524; GO:0005730; GO:0005829; GO:0010628; GO:0032088 31952 XM_044322607.1 14 4 0 36 23 NA NA NA NA NA NA 31953 XM_044319385.1 12 0 22 0 0 NA NA NA NA NA NA 31954 XM_044311046.1 31 7 11 21 22 NA NA NA NA NA NA 31955 XM_044328357.1 0 1 6 1 14 NA NA NA NA NA NA 31956 XM_029347165.2 2973 1614 1065 1873 1279 D2XV59 0 GTP-binding protein 1 Rattus norvegicus (Rat) GTP metabolic process [GO:0046039]; positive regulation of mRNA catabolic process [GO:0061014]; translational elongation [GO:0006414] GO:0000177; GO:0003746; GO:0003924; GO:0005525; GO:0005829; GO:0006414; GO:0046039; GO:0061014 31957 XM_044324316.1 171 71 57 94 72 NA NA NA NA NA NA 31958 XM_029342726.2 4636 2951 2233 2940 2052 Q9R1K5 0 Fizzy-related protein homolog (Fzr) (Cdh1/Hct1 homolog) Mus musculus (Mouse) anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; DNA repair [GO:0006281]; lens fiber cell differentiation [GO:0070306]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; negative regulation of cellular senescence [GO:2000773]; positive regulation of anaphase-promoting complex-dependent catabolic process [GO:1905786]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; protein ubiquitination [GO:0016567]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of meiotic nuclear division [GO:0040020] GO:0005654; GO:0005680; GO:0006281; GO:0007095; GO:0008284; GO:0010997; GO:0016567; GO:0031145; GO:0031965; GO:0040020; GO:0051301; GO:0051603; GO:0070306; GO:1904668; GO:1905786; GO:1990757; GO:2000773 31959 XM_029334458.2 0 0 170 250 0 Q26636 2.56e-124 Cathepsin L (EC 3.4.22.15) [Cleaved into: Cathepsin L heavy chain; Cathepsin L light chain] Sarcophaga peregrina (Flesh fly) (Boettcherisca peregrina) cell differentiation [GO:0030154]; proteolysis [GO:0006508] GO:0004197; GO:0005764; GO:0006508; GO:0030154 31960 XM_029332429.2 3 0 4 0 11 Q5QD04 1.53e-22 Trace amine-associated receptor 9 (TaR-9) (Trace amine receptor 9) (mTaar9) Mus musculus (Mouse) NA GO:0001594; GO:0005886 31961 XM_029330159.2 1111 722 373 819 756 O81916 1.29e-27 Uncharacterized calcium-binding protein At1g02270 Arabidopsis thaliana (Mouse-ear cress) NA GO:0000175; GO:0005509; GO:0005634; GO:0016020 31962 XM_044316077.1 156 20 95 44 265 NA NA NA NA NA NA 31963 XM_029352601.2 240 170 30 143 60 Q5YLH5 2.96e-29 Homeobox protein Hox-A6 Gallus gallus (Chicken) anterior/posterior pattern specification [GO:0009952]; embryonic skeletal system development [GO:0048706]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0009952; GO:0016607; GO:0048706 31964 XM_029329978.2 15 4 54 0 1 Q32LL6 9.58e-43 MORN repeat-containing protein 5 Bos taurus (Bovine) NA NA 31965 XR_006396051.1 87 29 197 182 392 NA NA NA NA NA NA 31966 XM_044311586.1 58 0 8 0 27 NA NA NA NA NA NA 31967 XM_029325149.2 4187 6630 2116 3244 5021 P61258 1.76e-112 Proliferating cell nuclear antigen (PCNA) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) base-excision repair, gap-filling [GO:0006287]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; epithelial cell differentiation [GO:0030855]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of DNA-directed DNA polymerase activity [GO:1900264]; replication fork processing [GO:0031297]; translesion synthesis [GO:0019985] GO:0000122; GO:0000307; GO:0000701; GO:0000785; GO:0001673; GO:0003682; GO:0003684; GO:0005652; GO:0005813; GO:0006287; GO:0006298; GO:0008022; GO:0016604; GO:0019985; GO:0030337; GO:0030855; GO:0030971; GO:0031297; GO:0032077; GO:0032139; GO:0032405; GO:0034644; GO:0035035; GO:0042802; GO:0043596; GO:0043626; GO:0045739; GO:0045740; GO:0070182; GO:0070557; GO:0071466; GO:1900264; GO:1902990 31968 XM_029344856.2 1200 296 660 560 607 Q6PF45 6.55e-60 Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Solute carrier family 32 member 1) (Vesicular GABA transporter) (xVIAAT) Xenopus laevis (African clawed frog) beta-alanine transport [GO:0001762]; gamma-aminobutyric acid import [GO:0051939]; gamma-aminobutyric acid transport [GO:0015812]; glycine transport [GO:0015816]; neurotransmitter transport [GO:0006836] GO:0001762; GO:0006836; GO:0008021; GO:0015185; GO:0015187; GO:0015812; GO:0015816; GO:0030659; GO:0042995; GO:0051939; GO:0098793; GO:0140799; GO:0140800 31969 XM_044316445.1 165 59 122 57 531 NA NA NA NA NA NA 31970 XM_029347959.2 0 0 6 4 2 Q86V86 1.06e-58 Serine/threonine-protein kinase pim-3 (EC 2.7.11.1) Homo sapiens (Human) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; negative regulation of apoptotic process [GO:0043066]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of mitotic cell cycle [GO:0007346] GO:0004674; GO:0005524; GO:0005737; GO:0005829; GO:0006468; GO:0006915; GO:0007049; GO:0007346; GO:0043066; GO:0046777; GO:0061179; GO:0106310 31971 XM_044327417.1 39 59 12 24 26 NA NA NA NA NA NA 31972 XM_029324303.2 47 37 27 63 39 Q5ZKY0 2.68e-61 Endosomal/lysosomal proton channel TMEM175 (Transmembrane protein 175) Gallus gallus (Chicken) lysosomal lumen pH elevation [GO:0035752]; neuron cellular homeostasis [GO:0070050]; phagosome-lysosome fusion [GO:0090385]; potassium ion transmembrane transport [GO:0071805]; proton transmembrane transport [GO:1902600]; regulation of lysosomal lumen pH [GO:0035751] GO:0005267; GO:0005764; GO:0005765; GO:0005768; GO:0010008; GO:0015252; GO:0022841; GO:0035751; GO:0035752; GO:0050544; GO:0070050; GO:0071805; GO:0090385; GO:1902600 31973 XM_044311088.1 27 0 0 0 0 NA NA NA NA NA NA 31974 XR_006395908.1 389 785 361 260 268 NA NA NA NA NA NA 31975 XM_029324221.2 11 17 3 75 46 P0DXC0 3.5e-109 NA NA NA NA 31976 XM_044313824.1 16 0 0 0 16 NA NA NA NA NA NA 31977 XM_029330125.2 162 0 55 147 0 Q14155 1.9e-126 Rho guanine nucleotide exchange factor 7 (Beta-Pix) (COOL-1) (PAK-interacting exchange factor beta) (p85) Homo sapiens (Human) ephrin receptor signaling pathway [GO:0048013]; focal adhesion assembly [GO:0048041]; Golgi organization [GO:0007030]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; negative regulation of microtubule nucleation [GO:1905833]; nervous system development [GO:0007399]; positive regulation of apoptotic process [GO:0043065]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of GTPase activity [GO:0043547]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of GTP binding [GO:1904424]; signal transduction [GO:0007165] GO:0001726; GO:0005085; GO:0005737; GO:0005813; GO:0005829; GO:0005925; GO:0005938; GO:0007030; GO:0007165; GO:0007399; GO:0010763; GO:0019901; GO:0030027; GO:0030032; GO:0032991; GO:0035556; GO:0043005; GO:0043015; GO:0043025; GO:0043065; GO:0043547; GO:0048013; GO:0048041; GO:0097431; GO:0098794; GO:1900026; GO:1904424; GO:1905833; GO:2000394 31978 XM_044312165.1 14 0 51 7 69 NA NA NA NA NA NA 31979 XM_044328034.1 865 571 945 1718 908 O54922 1.91e-162 Exocyst complex component 7 (Exocyst complex component Exo70) (rExo70) Rattus norvegicus (Rat) exocytosis [GO:0006887]; protein transport [GO:0015031]; regulation of entry of bacterium into host cell [GO:2000535] GO:0000145; GO:0005546; GO:0005815; GO:0005829; GO:0006887; GO:0015031; GO:0032584; GO:0034451; GO:0090543; GO:2000535 31980 XM_044320779.1 0 3 0 0 6 NA NA NA NA NA NA 31981 XM_044308858.1 97 90 82 117 23 NA NA NA NA NA NA 31982 XM_044318404.1 7 12 12 47 17 NA NA NA NA NA NA 31983 XM_029343356.2 1960 1911 1242 1393 470 NA NA NA NA NA NA 31984 XM_029332352.2 138 231 77 175 179 Q8BG58 3.76e-53 Transmembrane prolyl 4-hydroxylase (P4H-TM) (EC 1.14.11.29) (Hypoxia-inducible factor prolyl hydroxylase 4) (HIF-PH4) (HIF-prolyl hydroxylase 4) (HPH-4) Mus musculus (Mouse) peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; regulation of erythrocyte differentiation [GO:0045646] GO:0004656; GO:0005506; GO:0005509; GO:0005783; GO:0005789; GO:0016706; GO:0018401; GO:0031418; GO:0045646 31985 XM_044320798.1 303 215 88 577 115 NA NA NA NA NA NA 31986 XM_044319839.1 0 153 42 56 0 NA NA NA NA NA NA 31987 XM_044314090.1 0 0 12 1 2 NA NA NA NA NA NA 31988 XM_044307589.1 323 297 49 339 76 NA NA NA NA NA NA 31989 XM_044311504.1 93 0 53 0 256 NA NA NA NA NA NA 31990 XM_044326143.1 0 3 6 0 0 Q9TXJ8 1.36e-31 Putative ATP-dependent DNA helicase Q1 (EC 3.6.4.12) Caenorhabditis elegans DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724] GO:0000724; GO:0003676; GO:0005524; GO:0005634; GO:0005694; GO:0005737; GO:0006268; GO:0006281; GO:0006310; GO:0009378; GO:0016887; GO:0032508; GO:0043138 31991 XM_044325306.1 480 316 296 666 535 Q6IE24 4.39e-120 Inactive ubiquitin carboxyl-terminal hydrolase 54 (Inactive ubiquitin-specific peptidase 54) Rattus norvegicus (Rat) protein deubiquitination [GO:0016579] GO:0004843; GO:0016579 31992 XM_029351082.2 16 0 0 8 42 NA NA NA NA NA NA 31993 XM_044309132.1 17 93 911 421 841 NA NA NA NA NA NA 31994 XM_044320338.1 0 0 30 14 0 Q804R0 9.9e-33 Transcription factor LBX2 (Ladybird homeobox 2) (Ladybird homeobox protein homolog 2) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic axis specification [GO:0000578]; muscle cell development [GO:0055001]; muscle cell differentiation [GO:0042692]; positive regulation of convergent extension involved in gastrulation [GO:1904105]; positive regulation of non-canonical Wnt signaling pathway [GO:2000052]; posterior lateral line neuromast deposition [GO:0048922]; posterior lateral line neuromast primordium migration [GO:0048920]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000578; GO:0000981; GO:0005634; GO:0006357; GO:0042692; GO:0048920; GO:0048922; GO:0055001; GO:0060828; GO:1904105; GO:1990837; GO:2000052 31995 XM_029337870.2 20 0 233 0 513 Q5FWR0 0 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.4.12) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) DNA double-strand break processing [GO:0000729] GO:0000729; GO:0003677; GO:0004386; GO:0005524; GO:0005634; GO:0016887; GO:0035861; GO:0043130; GO:0140658 31996 XM_044328059.1 1202 1086 899 1021 1165 NA NA NA NA NA NA 31997 XM_044321445.1 19 0 27 16 0 NA NA NA NA NA NA 31998 XM_044306937.1 697 516 337 503 642 Q6ZMV9 0 Kinesin-like protein KIF6 Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0003777; GO:0005524; GO:0005737; GO:0005871; GO:0005874; GO:0007018; GO:0008017; GO:0016887 31999 XM_029340749.2 0 0 0 21 0 Q6AX59 4.96e-70 Protein ABHD8 (EC 3.-.-.-) (Alpha/beta hydrolase domain-containing protein 8) (Abhydrolase domain-containing protein 8) Xenopus laevis (African clawed frog) NA GO:0016787 32000 XM_029357606.2 369 404 270 363 431 Q5E9Y5 3.04e-93 Decapping and exoribonuclease protein (DXO) (EC 3.6.1.-) (5'-3' exoribonuclease DXO) (EC 3.1.13.-) (Dom-3 homolog Z) (NAD-capped RNA hydrolase DXO) (DeNADding enzyme DXO) (EC 3.6.1.-) Bos taurus (Bovine) mRNA catabolic process [GO:0006402]; NAD-cap decapping [GO:0110155]; nuclear mRNA surveillance [GO:0071028]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; RNA destabilization [GO:0050779] GO:0000166; GO:0000287; GO:0000956; GO:0003729; GO:0005634; GO:0005829; GO:0006402; GO:0008409; GO:0034353; GO:0050779; GO:0071028; GO:0090305; GO:0110152; GO:0110155 32001 XM_044312925.1 101 0 0 0 0 F8W2M8 1.92e-175 Tripeptidyl-peptidase 1 (TPP-1) (EC 3.4.14.9) (Tripeptidyl aminopeptidase) (Tripeptidyl-peptidase I) (TPP-I) Danio rerio (Zebrafish) (Brachydanio rerio) central nervous system development [GO:0007417]; locomotory behavior [GO:0007626]; neurogenesis [GO:0022008]; proteolysis [GO:0006508] GO:0004175; GO:0004252; GO:0005764; GO:0006508; GO:0007417; GO:0007626; GO:0008240; GO:0022008; GO:0046872 32002 XR_006394831.1 842 775 469 911 252 NA NA NA NA NA NA 32003 XM_044317422.1 538 594 250 253 80 NA NA NA NA NA NA 32004 XM_029349612.2 24 6 0 19 24 NA NA NA NA NA NA 32005 XM_044324748.1 0 0 0 0 22 Q9UKP5 1.25e-94 A disintegrin and metalloproteinase with thrombospondin motifs 6 (ADAM-TS 6) (ADAM-TS6) (ADAMTS-6) (EC 3.4.24.-) Homo sapiens (Human) aorta development [GO:0035904]; cardiac septum development [GO:0003279]; coronary vasculature development [GO:0060976]; extracellular matrix organization [GO:0030198]; kidney development [GO:0001822]; proteolysis [GO:0006508] GO:0001822; GO:0003279; GO:0004222; GO:0005576; GO:0006508; GO:0008237; GO:0030198; GO:0031012; GO:0035904; GO:0046872; GO:0060976 32006 XM_029332629.2 1761 2826 2580 3701 3553 Q8IUR6 1.72e-34 CREB3 regulatory factor (Luman recruitment factor) (LRF) Homo sapiens (Human) negative regulation of endoplasmic reticulum unfolded protein response [GO:1900102]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of intracellular transport [GO:0032388]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein transport [GO:0051222]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; response to endoplasmic reticulum stress [GO:0034976]; response to unfolded protein [GO:0006986] GO:0000122; GO:0000977; GO:0000981; GO:0001228; GO:0005634; GO:0005654; GO:0005737; GO:0006357; GO:0006986; GO:0016604; GO:0032388; GO:0034976; GO:0045732; GO:0045944; GO:0051222; GO:1900102 32007 XM_044324098.1 10 0 24 0 62 NA NA NA NA NA NA 32008 XM_044316264.1 38 6 35 21 21 NA NA NA NA NA NA 32009 XM_029330209.2 90 65 71 334 336 P12527 1.1e-48 Polyunsaturated fatty acid 5-lipoxygenase (EC 1.13.11.-) (Arachidonate 5-lipoxygenase) (5-LO) (5-lipoxygenase) (EC 1.13.11.34) Rattus norvegicus (Rat) acute inflammatory response [GO:0002526]; arachidonic acid metabolic process [GO:0019369]; dendritic cell migration [GO:0036336]; glucose homeostasis [GO:0042593]; hepoxilin biosynthetic process [GO:0051122]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; leukocyte chemotaxis involved in inflammatory response [GO:0002232]; leukocyte migration involved in inflammatory response [GO:0002523]; leukotriene A4 biosynthetic process [GO:1901753]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; leukotriene production involved in inflammatory response [GO:0002540]; linoleic acid metabolic process [GO:0043651]; lipid oxidation [GO:0034440]; lipoxin biosynthetic process [GO:2001301]; lipoxygenase pathway [GO:0019372]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of inflammatory response [GO:0050728]; negative regulation of response to endoplasmic reticulum stress [GO:1903573]; negative regulation of sprouting angiogenesis [GO:1903671]; negative regulation of vascular wound healing [GO:0061044]; negative regulation of wound healing [GO:0061045]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cytochrome-c oxidase activity [GO:1904960]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of vasoconstriction [GO:0045907]; regulation of cellular response to oxidative stress [GO:1900407]; regulation of cytokine production involved in inflammatory response [GO:1900015]; regulation of fat cell differentiation [GO:0045598]; regulation of inflammatory response [GO:0050727]; regulation of inflammatory response to wounding [GO:0106014]; regulation of insulin secretion [GO:0050796]; regulation of reactive oxygen species biosynthetic process [GO:1903426]; response to hyperoxia [GO:0055093]; response to nutrient [GO:0007584]; sensory perception of pain [GO:0019233] GO:0001937; GO:0002232; GO:0002523; GO:0002526; GO:0002540; GO:0004051; GO:0004052; GO:0005506; GO:0005634; GO:0005635; GO:0005641; GO:0005737; GO:0005829; GO:0006691; GO:0006954; GO:0006959; GO:0007584; GO:0016363; GO:0016525; GO:0016702; GO:0016787; GO:0019233; GO:0019369; GO:0019370; GO:0019372; GO:0030425; GO:0030501; GO:0031965; GO:0034440; GO:0036336; GO:0036403; GO:0042383; GO:0042593; GO:0043651; GO:0045598; GO:0045907; GO:0048471; GO:0050727; GO:0050728; GO:0050796; GO:0051122; GO:0055093; GO:0061044; GO:0061045; GO:0106014; GO:1900015; GO:1900407; GO:1901753; GO:1903426; GO:1903573; GO:1903671; GO:1904960; GO:1904999; GO:2001301 32010 XM_044329325.1 6038 5517 1656 3185 2137 NA NA NA NA NA NA 32011 XM_029358359.2 0 0 77 0 0 Q3KP44 1.26e-63 Ankyrin repeat domain-containing protein 55 Homo sapiens (Human) NA NA 32012 XM_029331209.2 690 782 488 491 691 Q80Y44 0 Probable ATP-dependent RNA helicase DDX10 (EC 3.6.4.13) (DEAD box protein 10) Mus musculus (Mouse) anterior head development [GO:0097065]; rRNA processing [GO:0006364] GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0006364; GO:0016887; GO:0097065 32013 XM_029348473.2 1944 3384 1266 2493 1294 P62313 9.17e-46 U6 snRNA-associated Sm-like protein LSm6 Mus musculus (Mouse) maturation of SSU-rRNA [GO:0030490]; mRNA catabolic process [GO:0006402]; mRNA splicing, via spliceosome [GO:0000398]; tRNA processing [GO:0008033] GO:0000398; GO:0000932; GO:0003723; GO:0005634; GO:0005688; GO:0005730; GO:0005732; GO:0005737; GO:0006402; GO:0008033; GO:0030490; GO:0046540; GO:0046982; GO:0071005; GO:0120115 32014 XM_044327637.1 468 313 0 0 317 Q0P5W1 0 Vacuolar protein sorting-associated protein 8 homolog Mus musculus (Mouse) endosomal vesicle fusion [GO:0034058]; protein targeting to vacuole [GO:0006623] GO:0005769; GO:0006623; GO:0033263; GO:0034058; GO:0046872 32015 XM_044312249.1 36 10 27 0 0 NA NA NA NA NA NA 32016 XM_044309576.1 4 1 5 1 118 NA NA NA NA NA NA 32017 XM_029354096.2 2 0 0 7 11 P0CT39 2.7e-81 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 32018 XR_003826145.2 224 137 105 183 248 NA NA NA NA NA NA 32019 XR_006395465.1 0 3 0 0 30 NA NA NA NA NA NA 32020 XM_029338403.2 167 89 76 118 124 NA NA NA NA NA NA 32021 XM_029357678.2 603 431 350 486 691 NA NA NA NA NA NA 32022 XM_044308654.1 0 7 0 50 15 A8Y5U1 2.15e-45 RAB7A-interacting MON1-CCZ1 complex subunit 1 (UPF0600 protein C5orf51 homolog) Danio rerio (Zebrafish) (Brachydanio rerio) mitophagy [GO:0000423] GO:0000423; GO:0005829 32023 XM_044316719.1 86 91 64 198 0 P14207 9.07e-36 Folate receptor beta (FR-beta) (Folate receptor 2) (Folate receptor, fetal/placental) (Placental folate-binding protein) (FBP) Homo sapiens (Human) cell adhesion [GO:0007155]; folic acid transport [GO:0015884]; fusion of sperm to egg plasma membrane involved in single fertilization [GO:0007342]; inflammatory response [GO:0006954]; positive regulation of cell population proliferation [GO:0008284]; sperm-egg recognition [GO:0035036] GO:0005542; GO:0005576; GO:0005886; GO:0006954; GO:0007155; GO:0007342; GO:0008284; GO:0009897; GO:0009986; GO:0015884; GO:0035036; GO:0038023; GO:0061714 32024 XM_044321882.1 73 109 152 151 65 NA NA NA NA NA NA 32025 XM_044316006.1 369 162 44 333 280 NA NA NA NA NA NA 32026 XM_029326874.2 108 47 90 78 91 Q3SZ21 1.16e-51 Ribonuclease P protein subunit p30 (RNaseP protein p30) (RNase P subunit 2) Bos taurus (Bovine) RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; rRNA processing [GO:0006364]; tRNA 5'-leader removal [GO:0001682]; tRNA processing [GO:0008033] GO:0000172; GO:0001682; GO:0003723; GO:0004526; GO:0005655; GO:0006364; GO:0008033; GO:0033204; GO:0090502 32027 XM_029338173.2 93 61 49 174 110 P0DH96 7.61e-25 Calmodulin-4 (CaM-4) Arabidopsis thaliana (Mouse-ear cress) NA GO:0005509 32028 XM_029335760.2 0 156 61 0 117 Q5XFW6 3.49e-111 WD repeat-containing protein 6 Rattus norvegicus (Rat) G1 to G0 transition [GO:0070314]; insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009]; negative regulation of autophagy [GO:0010507]; negative regulation of cell population proliferation [GO:0008285]; tRNA methylation [GO:0030488] GO:0005737; GO:0008285; GO:0008286; GO:0010507; GO:0030488; GO:0032991; GO:0043560; GO:0048009; GO:0070314 32029 XM_044317669.1 73 67 69 142 108 Q5SPC5 0 Otoferlin (Fer-1-like protein 2) Danio rerio (Zebrafish) (Brachydanio rerio) neuromuscular process controlling balance [GO:0050885]; plasma membrane organization [GO:0007009]; response to auditory stimulus [GO:0010996]; sensory perception of sound [GO:0007605]; startle response [GO:0001964]; synaptic vesicle exocytosis [GO:0016079]; synaptic vesicle priming [GO:0016082] GO:0000139; GO:0001964; GO:0005509; GO:0005789; GO:0007009; GO:0007605; GO:0010996; GO:0016079; GO:0016082; GO:0016323; GO:0030672; GO:0035612; GO:0042995; GO:0048787; GO:0050885 32030 XM_044317669.1 73 67 69 142 108 Q5SPC5 2.85e-106 Otoferlin (Fer-1-like protein 2) Danio rerio (Zebrafish) (Brachydanio rerio) neuromuscular process controlling balance [GO:0050885]; plasma membrane organization [GO:0007009]; response to auditory stimulus [GO:0010996]; sensory perception of sound [GO:0007605]; startle response [GO:0001964]; synaptic vesicle exocytosis [GO:0016079]; synaptic vesicle priming [GO:0016082] GO:0000139; GO:0001964; GO:0005509; GO:0005789; GO:0007009; GO:0007605; GO:0010996; GO:0016079; GO:0016082; GO:0016323; GO:0030672; GO:0035612; GO:0042995; GO:0048787; GO:0050885 32031 XM_044317669.1 73 67 69 142 108 Q5SPC5 2.85e-106 Otoferlin (Fer-1-like protein 2) Danio rerio (Zebrafish) (Brachydanio rerio) neuromuscular process controlling balance [GO:0050885]; plasma membrane organization [GO:0007009]; response to auditory stimulus [GO:0010996]; sensory perception of sound [GO:0007605]; startle response [GO:0001964]; synaptic vesicle exocytosis [GO:0016079]; synaptic vesicle priming [GO:0016082] GO:0000139; GO:0001964; GO:0005509; GO:0005789; GO:0007009; GO:0007605; GO:0010996; GO:0016079; GO:0016082; GO:0016323; GO:0030672; GO:0035612; GO:0042995; GO:0048787; GO:0050885 32032 XM_029350422.2 1675 3485 1771 3429 3184 Q3M6C3 1.05e-68 Demethyl-4-deoxygadusol synthase (DDGS) (EC 4.2.3.154) Trichormus variabilis (strain ATCC 29413 / PCC 7937) (Anabaena variabilis) antibiotic biosynthetic process [GO:0017000] GO:0000166; GO:0016829; GO:0017000; GO:0046872 32033 XM_044313850.1 21 5 11 18 25 NA NA NA NA NA NA 32034 XM_044307178.1 55 26 5 41 29 NA NA NA NA NA NA 32035 XM_029331062.2 2276 1757 1340 2022 2001 G5EFS2 2.61e-52 NA NA NA NA 32036 XM_044323734.1 0 0 0 0 7 NA NA NA NA NA NA 32037 XM_029324008.2 20 8 19 2 47 NA NA NA NA NA NA 32038 XR_006396120.1 27 162 130 34 19 Q99570 0 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 32039 XR_006396120.1 27 162 130 34 19 Q99570 0 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 32040 XM_044324005.1 20 33 25 30 32 NA NA NA NA NA NA 32041 XM_029352100.2 244 243 132 391 216 NA NA NA NA NA NA 32042 XM_044329216.1 2402 4676 3134 3406 2169 NA NA NA NA NA NA 32043 XM_029332706.2 108 64 60 53 56 NA NA NA NA NA NA 32044 XM_044320973.1 1066 374 679 856 1048 Q9CWP6 1.47e-74 Motile sperm domain-containing protein 2 Mus musculus (Mouse) chemotaxis [GO:0006935]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of neutrophil chemotaxis [GO:0090023] GO:0005783; GO:0005789; GO:0005886; GO:0006935; GO:0012505; GO:0044232; GO:0090023; GO:0090026; GO:0140284 32045 XM_044308864.1 668 529 433 468 100 NA NA NA NA NA NA 32046 XR_006392943.1 41 2 25 5 151 NA NA NA NA NA NA 32047 XM_029339906.2 842 1179 684 1140 810 Q98925 1.64e-35 Interferon regulatory factor 2 (IRF-2) Gallus gallus (Chicken) immune system process [GO:0002376]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0002376; GO:0005634; GO:0006357 32048 XM_029335565.2 0 0 0 0 8 NA NA NA NA NA NA 32049 XM_029331193.2 185 119 64 260 0 NA NA NA NA NA NA 32050 XM_044315935.1 600 228 219 525 504 Q5TEA3 0 Dynein axonemal assembly factor 9 (DNAAF9) Homo sapiens (Human) NA NA 32051 XM_029339621.2 277 2 30 220 89 NA NA NA NA NA NA 32052 XM_044322713.1 1389 1525 828 901 1164 NA NA NA NA NA NA 32053 XR_006397591.1 1 0 1 6 14 NA NA NA NA NA NA 32054 XM_044328295.1 82 6 45 78 802 NA NA NA NA NA NA 32055 XM_029337167.2 49 0 0 0 14 NA NA NA NA NA NA 32056 XM_044311038.1 158 90 51 39 74 NA NA NA NA NA NA 32057 XM_044320068.1 47 79 34 149 98 A1L1W9 1.56e-24 Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10) Danio rerio (Zebrafish) (Brachydanio rerio) aromatic amino acid transport [GO:0015801]; thyroid hormone transport [GO:0070327] GO:0005302; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0070327 32058 XM_044310827.1 18 0 3 29 54 NA NA NA NA NA NA 32059 XR_006397423.1 0 0 19 3 4 NA NA NA NA NA NA 32060 XM_029330551.2 3184 2167 1273 3163 3551 Q8BX70 0 Intermembrane lipid transfer protein VPS13C (Vacuolar protein sorting-associated protein 13C) Mus musculus (Mouse) lipid transport [GO:0006869]; mitochondrion organization [GO:0007005]; negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:1905090]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]; response to insulin [GO:0032868] GO:0005741; GO:0005764; GO:0005765; GO:0005770; GO:0005789; GO:0005811; GO:0005829; GO:0006623; GO:0006869; GO:0007005; GO:0019898; GO:0031902; GO:0032127; GO:0032868; GO:0045053; GO:1905090 32061 XM_029330551.2 3184 2167 1273 3163 3551 Q8BX70 4.15e-139 Intermembrane lipid transfer protein VPS13C (Vacuolar protein sorting-associated protein 13C) Mus musculus (Mouse) lipid transport [GO:0006869]; mitochondrion organization [GO:0007005]; negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:1905090]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]; response to insulin [GO:0032868] GO:0005741; GO:0005764; GO:0005765; GO:0005770; GO:0005789; GO:0005811; GO:0005829; GO:0006623; GO:0006869; GO:0007005; GO:0019898; GO:0031902; GO:0032127; GO:0032868; GO:0045053; GO:1905090 32062 XM_044329167.1 24 0 48 48 215 A6QLE6 5.98e-179 Anoctamin-4 (Transmembrane protein 16D) Bos taurus (Bovine) chloride transmembrane transport [GO:1902476]; lipid transport [GO:0006869]; transmembrane transport [GO:0055085] GO:0005229; GO:0005254; GO:0005886; GO:0006869; GO:0046983; GO:0055085; GO:1902476 32063 XM_044311097.1 0 4 0 7 0 NA NA NA NA NA NA 32064 XM_029334053.2 375 140 101 227 0 Q9UKY4 0 Protein O-mannosyl-transferase 2 (EC 2.4.1.109) (Dolichyl-phosphate-mannose--protein mannosyltransferase 2) Homo sapiens (Human) positive regulation of protein O-linked glycosylation [GO:1904100]; protein O-linked mannosylation [GO:0035269] GO:0000030; GO:0004169; GO:0005654; GO:0005730; GO:0005783; GO:0005789; GO:0005829; GO:0035269; GO:0046872; GO:1904100 32065 XM_044319324.1 20 30 6 8 32 NA NA NA NA NA NA 32066 XM_029350863.2 26 59 35 84 19 NA NA NA NA NA NA 32067 XR_003827243.2 29 19 6 15 43 NA NA NA NA NA NA 32068 XM_044311654.1 1 3 0 2 85 B8VIU6 3.92e-70 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 32069 XM_029326981.2 6253 4737 3681 4755 3544 Q9UJX0 1.2e-117 Oxidative stress-induced growth inhibitor 1 (Bone marrow stromal cell-derived growth inhibitor) (BMSC-derived growth inhibitor) (Ovary, kidney and liver protein 38) (huOKL38) (Pregnancy-induced growth inhibitor OKL38) Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of cell growth [GO:0030308]; regulation of apoptotic process [GO:0042981]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127] GO:0008083; GO:0030154; GO:0030308; GO:0030334; GO:0042127; GO:0042981 32070 XM_029353638.2 12 0 0 0 0 NA NA NA NA NA NA 32071 XM_029338410.2 16 530 239 5 841 Q3SZL5 2.22e-76 GPI transamidase component PIG-S (Phosphatidylinositol-glycan biosynthesis class S protein) Bos taurus (Bovine) attachment of GPI anchor to protein [GO:0016255] GO:0016255; GO:0042765 32072 XM_029338671.2 750 818 837 997 735 NA NA NA NA NA NA 32073 XR_006393839.1 14 1 49 0 1 NA NA NA NA NA NA 32074 XM_029348940.2 102 103 111 272 131 O54852 3.91e-101 Potassium voltage-gated channel subfamily H member 7 (Ether-a-go-go-related gene potassium channel 3) (ERG-3) (Eag-related protein 3) (Ether-a-go-go-related protein 3) (Voltage-gated potassium channel subunit Kv11.3) Rattus norvegicus (Rat) circadian rhythm [GO:0007623]; membrane repolarization during action potential [GO:0086011]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391] GO:0005242; GO:0005249; GO:0005267; GO:0005886; GO:0006813; GO:0007623; GO:0034765; GO:0042391; GO:0044877; GO:0071805; GO:0086011 32075 XM_029344199.2 230 365 181 593 717 Q4HX89 8.19e-37 Protein BTN1 Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1) (Wheat head blight fungus) (Fusarium graminearum) amino acid transport [GO:0006865] GO:0005774; GO:0006865 32076 XM_044327171.1 0 0 1 38 28 NA NA NA NA NA NA 32077 XM_044321722.1 9 8 0 2 0 NA NA NA NA NA NA 32078 XM_044310602.1 3 15 0 12 27 NA NA NA NA NA NA 32079 XR_006395162.1 102 26 32 132 147 NA NA NA NA NA NA 32080 XM_044326358.1 82 328 125 36 0 NA NA NA NA NA NA 32081 XM_029347162.2 14 87 128 344 229 P70426 2.19e-37 GTP-binding protein Rit1 (EC 3.6.5.2) (Ras-like protein expressed in many tissues) (Ras-like without CAAX protein 1) Mus musculus (Mouse) Ras protein signal transduction [GO:0007265] GO:0003924; GO:0003925; GO:0005516; GO:0005525; GO:0005886; GO:0007265; GO:0019003 32082 XM_029327049.2 2 130 0 56 48 Q8R4K8 0 Pappalysin-1 (EC 3.4.24.79) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase) (Pregnancy-associated plasma protein A) (PAPP-A) Mus musculus (Mouse) cell surface receptor signaling pathway [GO:0007166]; female pregnancy [GO:0007565]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to dexamethasone [GO:0071548]; response to follicle-stimulating hormone [GO:0032354] GO:0004175; GO:0004222; GO:0005576; GO:0005615; GO:0006508; GO:0007166; GO:0007565; GO:0008237; GO:0030163; GO:0032354; GO:0046872; GO:0071548 32083 XM_029332747.2 601 150 443 499 528 NA NA NA NA NA NA 32084 XM_029346356.2 16 72 29 39 119 NA NA NA NA NA NA 32085 XM_044320887.1 24 59 11 54 22 NA NA NA NA NA NA 32086 XM_044327917.1 26 0 19 76 62 NA NA NA NA NA NA 32087 XM_029339026.2 4060 7284 3255 5822 5028 Q99JW4 1.41e-145 LIM and senescent cell antigen-like-containing domain protein 1 (Particularly interesting new Cys-His protein 1) (PINCH-1) Mus musculus (Mouse) cell-cell adhesion [GO:0098609]; cell-cell junction organization [GO:0045216]; cell-matrix adhesion [GO:0007160]; cholangiocyte proliferation [GO:1990705]; chordate embryonic development [GO:0043009]; establishment of protein localization [GO:0045184]; establishment or maintenance of cell polarity [GO:0007163]; hepatocyte apoptotic process [GO:0097284]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of cholangiocyte proliferation [GO:1904055]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of hepatocyte apoptotic process [GO:1903944]; negative regulation of hepatocyte proliferation [GO:2000346]; negative regulation of neural precursor cell proliferation [GO:2000178]; neural precursor cell proliferation [GO:0061351]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of GTPase activity [GO:0043547]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0005737; GO:0005886; GO:0005911; GO:0005925; GO:0007160; GO:0007163; GO:0007229; GO:0008270; GO:0010628; GO:0010811; GO:0019901; GO:0032991; GO:0033209; GO:0043009; GO:0043547; GO:0044877; GO:0045184; GO:0045216; GO:0045892; GO:0048471; GO:0051894; GO:0061351; GO:0097284; GO:0098609; GO:1900026; GO:1901224; GO:1903944; GO:1904055; GO:1990705; GO:2000178; GO:2000346; GO:2001046 32088 XM_029335139.2 2156 1965 880 1892 968 Q969V4 1.11e-140 Tektin-1 Homo sapiens (Human) cilium assembly [GO:0060271]; cilium movement involved in cell motility [GO:0060294] GO:0005634; GO:0005879; GO:0015630; GO:0031514; GO:0060271; GO:0060294 32089 XM_029355506.2 201 145 135 179 99 P42586 3.01e-40 Homeobox protein Nkx-2.2 (Homeobox protein NK-2 homolog B) Mus musculus (Mouse) astrocyte differentiation [GO:0048708]; cell development [GO:0048468]; cell differentiation [GO:0030154]; digestive tract development [GO:0048565]; endocrine pancreas development [GO:0031018]; negative regulation of neuron differentiation [GO:0045665]; nervous system development [GO:0007399]; neuroendocrine cell differentiation [GO:0061101]; neuron differentiation [GO:0030182]; neuron fate specification [GO:0048665]; oligodendrocyte development [GO:0014003]; oligodendrocyte differentiation [GO:0048709]; optic nerve development [GO:0021554]; pancreatic A cell fate commitment [GO:0003326]; pancreatic PP cell fate commitment [GO:0003329]; positive regulation of epithelial cell differentiation [GO:0030858]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; response to glucose [GO:0009749]; response to progesterone [GO:0032570]; smoothened signaling pathway [GO:0007224]; spinal cord motor neuron differentiation [GO:0021522]; spinal cord oligodendrocyte cell differentiation [GO:0021529]; spinal cord oligodendrocyte cell fate specification [GO:0021530]; type B pancreatic cell development [GO:0003323]; type B pancreatic cell differentiation [GO:0003309]; type B pancreatic cell fate commitment [GO:0003327]; ventral spinal cord interneuron fate determination [GO:0060580] GO:0000978; GO:0000981; GO:0000987; GO:0001228; GO:0003309; GO:0003323; GO:0003326; GO:0003327; GO:0003329; GO:0003700; GO:0005634; GO:0006355; GO:0006357; GO:0007224; GO:0007399; GO:0009749; GO:0010628; GO:0014003; GO:0021522; GO:0021529; GO:0021530; GO:0021554; GO:0030154; GO:0030182; GO:0030858; GO:0031018; GO:0032570; GO:0043565; GO:0045665; GO:0045666; GO:0045944; GO:0048468; GO:0048565; GO:0048665; GO:0048708; GO:0048709; GO:0048714; GO:0060580; GO:0061101 32090 XM_044320607.1 368 269 215 266 188 Q99JW2 7.67e-110 Aminoacylase-1 (ACY-1) (EC 3.5.1.14) (N-acyl-L-amino-acid amidohydrolase) Mus musculus (Mouse) amino acid metabolic process [GO:0006520] GO:0004046; GO:0005737; GO:0006520; GO:0042802; GO:0046872; GO:0070062 32091 XR_003825143.2 8 0 1 0 0 NA NA NA NA NA NA 32092 XM_044322992.1 21 3 0 9 0 NA NA NA NA NA NA 32093 XR_006392954.1 41 2 25 5 151 NA NA NA NA NA NA 32094 XM_029348780.2 615 660 520 1038 765 Q75Q39 4.73e-140 Mitochondrial import receptor subunit TOM70 (Mitochondrial precursor proteins import receptor) (Translocase of outer membrane 70 kDa subunit) (Translocase of outer mitochondrial membrane protein 70) Rattus norvegicus (Rat) activation of innate immune response [GO:0002218]; cellular response to virus [GO:0098586]; negative regulation of cell growth involved in cardiac muscle cell development [GO:0061052]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of protein import [GO:1904591]; protein import into mitochondrial matrix [GO:0030150]; protein insertion into mitochondrial inner membrane [GO:0045039]; protein targeting to mitochondrion [GO:0006626]; regulation of apoptotic process [GO:0042981]; response to thyroxine [GO:0097068] GO:0002218; GO:0002230; GO:0005739; GO:0005741; GO:0005742; GO:0006626; GO:0030150; GO:0030943; GO:0032728; GO:0042981; GO:0045039; GO:0061052; GO:0097068; GO:0098586; GO:1904591 32095 XM_044321669.1 152 32 34 224 187 Q86WI3 9.05e-33 Protein NLRC5 (Caterpiller protein 16.1) (CLR16.1) (Nucleotide-binding oligomerization domain protein 27) (Nucleotide-binding oligomerization domain protein 4) Homo sapiens (Human) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of type II interferon-mediated signaling pathway [GO:0060335]; regulation of kinase activity [GO:0043549]; response to bacterium [GO:0009617] GO:0000978; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0009617; GO:0032088; GO:0035556; GO:0043549; GO:0045087; GO:0045345; GO:0045944; GO:0051607; GO:0060335; GO:0060339; GO:0060340 32096 XM_029336592.2 0 0 0 0 90 Q5XIN3 1.71e-51 TRAF3-interacting protein 1 (Intraflagellar transport protein 54 homolog) (Microtubule-interacting protein associated with TRAF3) (MIP-T3) Rattus norvegicus (Rat) cilium assembly [GO:0060271]; defense response to virus [GO:0051607]; embryonic camera-type eye development [GO:0031076]; embryonic digit morphogenesis [GO:0042733]; embryonic heart tube development [GO:0035050]; intraciliary transport [GO:0042073]; kidney development [GO:0001822]; morphogenesis of a polarized epithelium [GO:0001738]; negative regulation of defense response to virus [GO:0050687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:1901621]; negative regulation of type I interferon production [GO:0032480]; neural tube patterning [GO:0021532]; post-anal tail morphogenesis [GO:0036342]; regulation of microtubule cytoskeleton organization [GO:0070507]; smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] GO:0001738; GO:0001822; GO:0001933; GO:0005813; GO:0005929; GO:0005930; GO:0008017; GO:0021532; GO:0030992; GO:0031076; GO:0031333; GO:0032480; GO:0032688; GO:0035050; GO:0035869; GO:0036064; GO:0036342; GO:0042073; GO:0042733; GO:0050687; GO:0051607; GO:0060271; GO:0060831; GO:0070507; GO:0097542; GO:0097546; GO:1901621 32097 XM_029336592.2 0 0 0 0 90 Q5XIN3 6.39e-47 TRAF3-interacting protein 1 (Intraflagellar transport protein 54 homolog) (Microtubule-interacting protein associated with TRAF3) (MIP-T3) Rattus norvegicus (Rat) cilium assembly [GO:0060271]; defense response to virus [GO:0051607]; embryonic camera-type eye development [GO:0031076]; embryonic digit morphogenesis [GO:0042733]; embryonic heart tube development [GO:0035050]; intraciliary transport [GO:0042073]; kidney development [GO:0001822]; morphogenesis of a polarized epithelium [GO:0001738]; negative regulation of defense response to virus [GO:0050687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:1901621]; negative regulation of type I interferon production [GO:0032480]; neural tube patterning [GO:0021532]; post-anal tail morphogenesis [GO:0036342]; regulation of microtubule cytoskeleton organization [GO:0070507]; smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] GO:0001738; GO:0001822; GO:0001933; GO:0005813; GO:0005929; GO:0005930; GO:0008017; GO:0021532; GO:0030992; GO:0031076; GO:0031333; GO:0032480; GO:0032688; GO:0035050; GO:0035869; GO:0036064; GO:0036342; GO:0042073; GO:0042733; GO:0050687; GO:0051607; GO:0060271; GO:0060831; GO:0070507; GO:0097542; GO:0097546; GO:1901621 32098 XM_029344715.2 260 190 200 231 309 Q8LET2 8.05e-37 Nudix hydrolase 11 (AtNUDT11) (EC 3.6.1.-) (Coenzyme A diphosphatase NUDT11) Arabidopsis thaliana (Mouse-ear cress) coenzyme A biosynthetic process [GO:0015937]; coenzyme A catabolic process [GO:0015938]; malonyl-CoA catabolic process [GO:2001294]; nucleoside phosphate metabolic process [GO:0006753] GO:0000210; GO:0003986; GO:0005778; GO:0005829; GO:0006753; GO:0008893; GO:0010945; GO:0015937; GO:0015938; GO:0046872; GO:2001294 32099 XM_029336436.2 336 171 177 275 376 Q5XIR4 5.12e-42 Coiled-coil domain-containing protein 33 Rattus norvegicus (Rat) NA GO:0005777 32100 XM_029351274.2 265 88 155 79 0 P60764 3.83e-26 Ras-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3) Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; cell projection assembly [GO:0030031]; cerebral cortex GABAergic interneuron development [GO:0021894]; cortical cytoskeleton organization [GO:0030865]; establishment or maintenance of cell polarity [GO:0007163]; homeostasis of number of cells within a tissue [GO:0048873]; neuromuscular process [GO:0050905]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; postsynaptic actin cytoskeleton organization [GO:0098974]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell morphogenesis [GO:0022604]; regulation of cell shape [GO:0008360]; regulation of neuron maturation [GO:0014041]; small GTPase mediated signal transduction [GO:0007264]; synaptic transmission, GABAergic [GO:0051932]; Wnt signaling pathway [GO:0016055] GO:0003924; GO:0003925; GO:0005525; GO:0005829; GO:0005856; GO:0005886; GO:0005938; GO:0007015; GO:0007163; GO:0007264; GO:0008360; GO:0012505; GO:0014041; GO:0016055; GO:0019901; GO:0021894; GO:0022604; GO:0030027; GO:0030031; GO:0030036; GO:0030426; GO:0030865; GO:0031175; GO:0031410; GO:0031941; GO:0032956; GO:0033630; GO:0042995; GO:0043005; GO:0043025; GO:0048306; GO:0048471; GO:0048873; GO:0050885; GO:0050905; GO:0051932; GO:0071944; GO:0098974; GO:0098978; GO:1900026 32101 XR_006391616.1 102 32 17 34 19 NA NA NA NA NA NA 32102 XM_044313467.1 47 1 52 647 38 NA NA NA NA NA NA 32103 XR_006394466.1 123 82 59 198 152 NA NA NA NA NA NA 32104 XM_044311144.1 545 239 410 500 1181 Q8QGX4 0 DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) Gallus gallus (Chicken) double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; immunoglobulin V(D)J recombination [GO:0033152]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; mitotic G1 DNA damage checkpoint signaling [GO:0031571]; protein phosphorylation [GO:0006468]; ribosome biogenesis [GO:0042254]; telomere maintenance [GO:0000723] GO:0000723; GO:0000724; GO:0004674; GO:0004677; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0006302; GO:0006303; GO:0006468; GO:0008630; GO:0031571; GO:0033152; GO:0042254; GO:0070419; GO:0106310 32105 XM_029331689.2 20 44 28 45 38 O75063 1.03e-140 Glycosaminoglycan xylosylkinase (EC 2.7.1.-) (Xylose kinase) Homo sapiens (Human) phosphorylation [GO:0016310]; proteoglycan biosynthetic process [GO:0030166] GO:0000139; GO:0005524; GO:0005654; GO:0005794; GO:0016301; GO:0016310; GO:0016773; GO:0030166; GO:0046872 32106 XM_044321830.1 1638 270 587 612 3103 NA NA NA NA NA NA 32107 XM_029350845.2 684 377 74 1305 807 NA NA NA NA NA NA 32108 XR_006395807.1 1718 1592 2008 1529 1453 NA NA NA NA NA NA 32109 XM_029357005.2 16 2 5 3 17 NA NA NA NA NA NA 32110 XM_044325394.1 37 23 11 31 86 P07911 5.15e-25 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Homo sapiens (Human) antibacterial innate immune response [GO:0140367]; apoptotic signaling pathway [GO:0097190]; autophagy [GO:0006914]; cellular calcium ion homeostasis [GO:0006874]; cellular chloride ion homeostasis [GO:0030644]; cellular defense response [GO:0006968]; cellular phosphate ion homeostasis [GO:0030643]; cellular response to unfolded protein [GO:0034620]; cellular sodium ion homeostasis [GO:0006883]; chaperone-mediated protein folding [GO:0061077]; citric acid secretion [GO:0046720]; collecting duct development [GO:0072044]; connective tissue replacement [GO:0097709]; creatinine homeostasis [GO:0097273]; defense response to Gram-negative bacterium [GO:0050829]; endoplasmic reticulum organization [GO:0007029]; glomerular filtration [GO:0003094]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; juxtaglomerular apparatus development [GO:0072051]; leukocyte cell-cell adhesion [GO:0007159]; lipid metabolic process [GO:0006629]; metanephric ascending thin limb development [GO:0072218]; metanephric distal convoluted tubule development [GO:0072221]; metanephric thick ascending limb development [GO:0072233]; micturition [GO:0060073]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell population proliferation [GO:0008285]; neutrophil migration [GO:1990266]; organ or tissue specific immune response [GO:0002251]; peptidyl-threonine phosphorylation [GO:0018107]; potassium ion homeostasis [GO:0055075]; protein localization to vacuole [GO:0072665]; protein transport into plasma membrane raft [GO:0044861]; regulation of blood pressure [GO:0008217]; regulation of protein transport [GO:0051223]; regulation of urine volume [GO:0035809]; renal sodium ion absorption [GO:0070294]; renal urate salt excretion [GO:0097744]; renal water homeostasis [GO:0003091]; response to lipopolysaccharide [GO:0032496]; response to water deprivation [GO:0009414]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; ubiquitin-dependent ERAD pathway [GO:0030433]; urate transport [GO:0015747]; urea transmembrane transport [GO:0071918] GO:0000922; GO:0002251; GO:0003091; GO:0003094; GO:0005201; GO:0005509; GO:0005615; GO:0005783; GO:0005796; GO:0005929; GO:0006629; GO:0006874; GO:0006883; GO:0006914; GO:0006954; GO:0006968; GO:0007029; GO:0007157; GO:0007159; GO:0008217; GO:0008285; GO:0008380; GO:0009410; GO:0009414; GO:0009986; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0018107; GO:0019864; GO:0019898; GO:0030433; GO:0030643; GO:0030644; GO:0032496; GO:0033209; GO:0033555; GO:0034620; GO:0035809; GO:0044861; GO:0046720; GO:0050829; GO:0051223; GO:0055075; GO:0060073; GO:0060170; GO:0061077; GO:0070062; GO:0070294; GO:0071918; GO:0072044; GO:0072051; GO:0072218; GO:0072221; GO:0072233; GO:0072665; GO:0097190; GO:0097273; GO:0097709; GO:0097744; GO:0140367; GO:1990266 32111 XM_044307753.1 14 9 4 5 9 Q9UJA9 2.58e-82 Ectonucleotide pyrophosphatase/phosphodiesterase family member 5 (E-NPP 5) (NPP-5) (EC 3.1.-.-) Homo sapiens (Human) cell communication [GO:0007154] GO:0000210; GO:0005576; GO:0005886; GO:0007154; GO:0008270 32112 XM_044324530.1 1806 1059 672 925 686 Q6NRH1 1.08e-125 DDB1- and CUL4-associated factor 8 (WD repeat-containing protein 42A) Xenopus laevis (African clawed frog) NA GO:0005634; GO:0005737 32113 XM_044312444.1 12 0 9 0 12 P04323 7.12e-62 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 32114 XR_006393082.1 41 2 25 5 151 NA NA NA NA NA NA 32115 XM_044321117.1 54 40 215 116 121 Q9H1A4 0 Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Mitotic checkpoint regulator) (Testis-specific gene 24 protein) Homo sapiens (Human) anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; metaphase/anaphase transition of mitotic cell cycle [GO:0007091]; protein K11-linked ubiquitination [GO:0070979]; regulation of meiotic cell cycle [GO:0051445]; regulation of mitotic cell cycle [GO:0007346] GO:0005654; GO:0005680; GO:0005829; GO:0007091; GO:0007346; GO:0031145; GO:0051301; GO:0051445; GO:0060090; GO:0070979 32116 XM_029350413.2 0 0 18 6 19 NA NA NA NA NA NA 32117 XR_006397695.1 18 39 61 69 82 Q26636 1.8e-30 Cathepsin L (EC 3.4.22.15) [Cleaved into: Cathepsin L heavy chain; Cathepsin L light chain] Sarcophaga peregrina (Flesh fly) (Boettcherisca peregrina) cell differentiation [GO:0030154]; proteolysis [GO:0006508] GO:0004197; GO:0005764; GO:0006508; GO:0030154 32118 XR_003825207.2 0 0 8 0 22 NA NA NA NA NA NA 32119 XM_044310242.1 0 10 13 13 32 Q5F371 1.61e-52 Protein strawberry notch homolog 1 Gallus gallus (Chicken) regulation of DNA-templated transcription [GO:0006355]; regulation of response to stimulus [GO:0048583] GO:0005634; GO:0006355; GO:0031490; GO:0042393; GO:0048583 32120 XM_044310242.1 0 10 13 13 32 Q5F371 1.61e-52 Protein strawberry notch homolog 1 Gallus gallus (Chicken) regulation of DNA-templated transcription [GO:0006355]; regulation of response to stimulus [GO:0048583] GO:0005634; GO:0006355; GO:0031490; GO:0042393; GO:0048583 32121 XM_044314164.1 114 1 58 51 125 Q9I8C7 5.95e-77 Neuronal acetylcholine receptor subunit alpha-10 (Alpha 10 nAChR) (Nicotinic acetylcholine receptor subunit alpha-10) (NACHR alpha-10) Gallus gallus (Chicken) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; response to auditory stimulus [GO:0010996]; signal transduction [GO:0007165] GO:0004888; GO:0005231; GO:0005262; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0010996; GO:0022848; GO:0030594; GO:0034220; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051899; GO:1904315 32122 XM_044308812.1 43 21 28 15 10 NA NA NA NA NA NA 32123 XM_029358308.2 111 79 36 37 77 Q9QYS2 0 Metabotropic glutamate receptor 3 (mGluR3) Mus musculus (Mouse) G protein-coupled glutamate receptor signaling pathway [GO:0007216]; gene expression [GO:0010467]; modulation of chemical synaptic transmission [GO:0050804]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; regulation of sensory perception of pain [GO:0051930]; regulation of synaptic transmission, glutamatergic [GO:0051966]; sensory perception of pain [GO:0019233]; synaptic transmission, glutamatergic [GO:0035249] GO:0001640; GO:0001641; GO:0005246; GO:0005886; GO:0007216; GO:0010467; GO:0014069; GO:0019233; GO:0030424; GO:0035249; GO:0042734; GO:0043005; GO:0043197; GO:0045211; GO:0048786; GO:0050804; GO:0051930; GO:0051966; GO:0097110; GO:0097449; GO:0098978; GO:0099170 32124 XM_029356256.2 224 184 54 139 255 Q5R733 2.16e-127 Cytoplasmic polyadenylation element-binding protein 1 (CPE-BP1) (CPE-binding protein 1) (CPEB-1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cellular response to amino acid stimulus [GO:0071230]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; mRNA processing [GO:0006397]; negative regulation of cytoplasmic translation [GO:2000766]; positive regulation of mRNA polyadenylation [GO:1900365] GO:0000900; GO:0000932; GO:0005634; GO:0005737; GO:0006397; GO:0014069; GO:0016020; GO:0030425; GO:0032869; GO:0035925; GO:0046872; GO:0071230; GO:0071456; GO:1900365; GO:1990904; GO:2000766 32125 XM_029336744.2 5937 4967 2586 3965 3724 Q5RC90 7.36e-75 Neuronal calcium sensor 1 (NCS-1) (Frequenin homolog) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) regulation of neuron projection development [GO:0010975] GO:0005245; GO:0005509; GO:0005794; GO:0005886; GO:0010975; GO:0014069; GO:0048471 32126 XM_044323097.1 3 4 2 2 21 NA NA NA NA NA NA 32127 XM_029347147.2 114 59 194 56 106 A0JPE1 2.72e-28 Divergent protein kinase domain 1B (Protein FAM69B) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005789 32128 XM_029341289.2 1545 614 681 913 620 NA NA NA NA NA NA 32129 XM_044318615.1 1383 629 440 1011 257 NA NA NA NA NA NA 32130 XM_044324383.1 33 55 114 0 0 NA NA NA NA NA NA 32131 XM_044322485.1 26 0 0 82 0 NA NA NA NA NA NA 32132 XM_029330842.2 1493 1101 779 1862 251 Q9Y2E4 0 Disco-interacting protein 2 homolog C (DIP2 homolog C) Homo sapiens (Human) NA NA 32133 XR_006397781.1 25 2 13 18 27 NA NA NA NA NA NA 32134 XM_044324074.1 56 156 0 22 39 NA NA NA NA NA NA 32135 XM_029357149.2 7 5 0 6 0 NA NA NA NA NA NA 32136 XM_029330434.2 70 61 42 62 44 G5EDU6 3.12e-47 Transcription factor ovo-like homolog lin-48 (Abnormal cell lineage protein 48) Caenorhabditis elegans epidermal cell differentiation [GO:0009913]; hindgut morphogenesis [GO:0007442]; nematode male tail tip morphogenesis [GO:0045138]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0003700; GO:0005634; GO:0006355; GO:0006357; GO:0007442; GO:0009913; GO:0045138; GO:0046872 32137 XM_029354316.2 6 0 38 5 181 NA NA NA NA NA NA 32138 XM_044321333.1 0 0 10 0 0 Q13416 1.79e-112 Origin recognition complex subunit 2 Homo sapiens (Human) DNA replication initiation [GO:0006270]; negative regulation of transcription by RNA polymerase II [GO:0000122] GO:0000122; GO:0000781; GO:0000792; GO:0000808; GO:0000939; GO:0003688; GO:0005634; GO:0005654; GO:0005664; GO:0005813; GO:0006270; GO:0016020 32139 XM_029330857.2 2186 2499 2339 2636 1816 Q6AYB8 6.86e-33 Golgin-45 (Basic leucine zipper nuclear factor 1) Rattus norvegicus (Rat) Golgi organization [GO:0007030]; Golgi to plasma membrane protein transport [GO:0043001] GO:0000139; GO:0005634; GO:0005794; GO:0007030; GO:0019899; GO:0031625; GO:0043001 32140 XM_029351476.2 17 11 0 0 0 Q5TJF5 7.27e-68 (3R)-3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.n12) (17-beta-hydroxysteroid dehydrogenase 8) (17-beta-HSD 8) (3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit) (KAR alpha subunit) (3-oxoacyl-[acyl-carrier-protein] reductase) (Estradiol 17-beta-dehydrogenase 8) (EC 1.1.1.62) (Testosterone 17-beta-dehydrogenase 8) (EC 1.1.1.239) Canis lupus familiaris (Dog) (Canis familiaris) androgen metabolic process [GO:0008209]; estrogen biosynthetic process [GO:0006703]; fatty acid biosynthetic process [GO:0006633]; protein heterotetramerization [GO:0051290] GO:0004303; GO:0005740; GO:0005759; GO:0005886; GO:0006633; GO:0006703; GO:0008209; GO:0016616; GO:0044594; GO:0047035; GO:0048038; GO:0051290; GO:0070404; GO:0106386; GO:1990204 32141 XM_029324592.2 1024 869 791 1609 1323 Q69ZJ7 0 Guanine nucleotide exchange factor subunit RIC1 (Protein RIC1 homolog) (RAB6A-GEF complex partner protein 1) Mus musculus (Mouse) cranial skeletal system development [GO:1904888]; intracellular protein transport [GO:0006886]; negative regulation of protein catabolic process [GO:0042177]; positive regulation of GTPase activity [GO:0043547]; regulation of extracellular matrix constituent secretion [GO:0003330]; retrograde transport, endosome to Golgi [GO:0042147] GO:0000139; GO:0003330; GO:0005085; GO:0005829; GO:0006886; GO:0016020; GO:0031267; GO:0032991; GO:0034066; GO:0042147; GO:0042177; GO:0043547; GO:1904888 32142 XM_029334865.2 163 37 246 712 282 NA NA NA NA NA NA 32143 XM_029355290.1 0 3 0 9 0 NA NA NA NA NA NA 32144 XM_044319083.1 219 427 78 220 206 NA NA NA NA NA NA 32145 XR_003825640.2 43 41 8 60 49 NA NA NA NA NA NA 32146 XM_044319159.1 152 140 154 174 308 A8KBG2 2.11e-21 Post-GPI attachment to proteins factor 2 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) GPI anchor biosynthetic process [GO:0006506] GO:0000139; GO:0005789; GO:0006506 32147 XM_044317225.1 1266 1342 512 1195 791 NA NA NA NA NA NA 32148 XM_029340163.2 334 238 365 249 404 Q80VY9 0 ATP-dependent RNA helicase DHX33 (EC 3.6.4.13) (DEAH box protein 33) Mus musculus (Mouse) positive regulation of MAPK cascade [GO:0043410]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NLRP3 inflammasome complex assembly [GO:1900227]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of type I interferon production [GO:0032481]; translational initiation [GO:0006413] GO:0000182; GO:0003723; GO:0003724; GO:0003725; GO:0003729; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0006413; GO:0016887; GO:0032481; GO:0043023; GO:0043410; GO:0045943; GO:0051092; GO:0072559; GO:0140297; GO:1900227 32149 XM_029342631.2 131 48 81 109 132 NA NA NA NA NA NA 32150 XM_029341481.2 0 135 0 0 0 Q6INE3 5.83e-67 Toll-interacting protein B Xenopus laevis (African clawed frog) autophagy [GO:0006914]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; phosphorylation [GO:0016310] GO:0005737; GO:0006914; GO:0006954; GO:0016310; GO:0043130; GO:0045087 32151 XM_044321002.1 95 0 0 768 723 A2ASQ1 7.7e-22 Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment (C90); Agrin C-terminal 22 kDa fragment (C22)] Mus musculus (Mouse) animal organ morphogenesis [GO:0009887]; cell differentiation [GO:0030154]; chemical synaptic transmission [GO:0007268]; motor neuron apoptotic process [GO:0097049]; negative regulation of P-type sodium:potassium-exchanging transporter activity [GO:1903407]; negative regulation of sodium ion export across plasma membrane [GO:1903277]; neuromuscular junction development [GO:0007528]; neurotransmitter receptor metabolic process [GO:0045213]; plasma membrane organization [GO:0007009]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of motor neuron apoptotic process [GO:2000673]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein binding [GO:0032092]; positive regulation of protein geranylgeranylation [GO:2000541]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of synaptic assembly at neuromuscular junction [GO:0045887]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor clustering [GO:0043113]; regulation of axon guidance [GO:1902667]; regulation of cardiac muscle cell membrane potential [GO:0086036]; regulation of cardiac muscle contraction [GO:0055117]; regulation of GTPase activity [GO:0043087]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of protein phosphorylation [GO:0001932]; regulation of synapse organization [GO:0050807]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse assembly [GO:0007416]; tissue development [GO:0009888] GO:0001932; GO:0001934; GO:0002162; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005796; GO:0007009; GO:0007268; GO:0007416; GO:0007528; GO:0009887; GO:0009888; GO:0009986; GO:0030154; GO:0030548; GO:0032092; GO:0033691; GO:0035374; GO:0036122; GO:0042030; GO:0042383; GO:0043083; GO:0043087; GO:0043113; GO:0043395; GO:0043547; GO:0044295; GO:0044325; GO:0045202; GO:0045213; GO:0045887; GO:0045944; GO:0050431; GO:0050731; GO:0050807; GO:0051491; GO:0055117; GO:0061098; GO:0062023; GO:0070507; GO:0071340; GO:0086036; GO:0097049; GO:0098978; GO:1902667; GO:1903277; GO:1903407; GO:2000541; GO:2000673 32152 XM_044315472.1 15 10 8 10 10 NA NA NA NA NA NA 32153 XM_044323692.1 30 0 0 0 12 NA NA NA NA NA NA 32154 XM_029352326.2 15 44 16 26 23 NA NA NA NA NA NA 32155 XM_044313641.1 9 12 6 4 0 Q9QXW0 1.44e-51 F-box/LRR-repeat protein 6 (F-box and leucine-rich repeat protein 6) (F-box protein FBL6) Mus musculus (Mouse) entrainment of circadian clock by photoperiod [GO:0043153]; G2/M transition of mitotic cell cycle [GO:0000086]; regulation of cell cycle [GO:0051726]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0000086; GO:0005634; GO:0005829; GO:0019005; GO:0031146; GO:0043153; GO:0051726 32156 XM_029345481.2 4517 4044 4201 3223 1007 NA NA NA NA NA NA 32157 XM_044320217.1 748 576 292 459 351 NA NA NA NA NA NA 32158 XR_003824339.2 15 12 36 20 90 NA NA NA NA NA NA 32159 XM_029342053.2 4149 3413 461 4040 4336 Q60520 0 Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a) Mus musculus (Mouse) activation of innate immune response [GO:0002218]; aging [GO:0007568]; cellular response to dopamine [GO:1903351]; cellular response to glucose stimulus [GO:0071333]; cerebral cortex neuron differentiation [GO:0021895]; DNA replication [GO:0006260]; hematopoietic progenitor cell differentiation [GO:0002244]; histone deacetylation [GO:0016575]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell migration [GO:0030336]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of histone H3-K27 acetylation [GO:1901675]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of stem cell population maintenance [GO:1902455]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of heterochromatin formation [GO:0031453]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deacetylation [GO:0006476]; protein localization [GO:0008104]; regulation of axon extension [GO:0030516]; regulation of DNA-templated transcription [GO:0006355]; regulation of hormone levels [GO:0010817]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to methylglyoxal [GO:0051595]; response to organonitrogen compound [GO:0010243]; rhythmic process [GO:0048511] GO:0000118; GO:0000122; GO:0000776; GO:0000785; GO:0001701; GO:0002218; GO:0002230; GO:0002244; GO:0003677; GO:0003682; GO:0003713; GO:0003714; GO:0003723; GO:0005634; GO:0005654; GO:0005667; GO:0005730; GO:0006260; GO:0006355; GO:0006476; GO:0007568; GO:0008104; GO:0010243; GO:0010817; GO:0010971; GO:0016575; GO:0016580; GO:0017053; GO:0021895; GO:0030336; GO:0030512; GO:0030516; GO:0031453; GO:0032991; GO:0042754; GO:0043066; GO:0043619; GO:0044877; GO:0045666; GO:0045892; GO:0045944; GO:0048511; GO:0051595; GO:0061629; GO:0071333; GO:0140416; GO:1900181; GO:1901675; GO:1902455; GO:1902459; GO:1903351; GO:2000678 32160 XM_029342053.2 4149 3413 461 4040 4336 Q60520 8.73e-39 Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a) Mus musculus (Mouse) activation of innate immune response [GO:0002218]; aging [GO:0007568]; cellular response to dopamine [GO:1903351]; cellular response to glucose stimulus [GO:0071333]; cerebral cortex neuron differentiation [GO:0021895]; DNA replication [GO:0006260]; hematopoietic progenitor cell differentiation [GO:0002244]; histone deacetylation [GO:0016575]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell migration [GO:0030336]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of histone H3-K27 acetylation [GO:1901675]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of stem cell population maintenance [GO:1902455]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of heterochromatin formation [GO:0031453]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deacetylation [GO:0006476]; protein localization [GO:0008104]; regulation of axon extension [GO:0030516]; regulation of DNA-templated transcription [GO:0006355]; regulation of hormone levels [GO:0010817]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to methylglyoxal [GO:0051595]; response to organonitrogen compound [GO:0010243]; rhythmic process [GO:0048511] GO:0000118; GO:0000122; GO:0000776; GO:0000785; GO:0001701; GO:0002218; GO:0002230; GO:0002244; GO:0003677; GO:0003682; GO:0003713; GO:0003714; GO:0003723; GO:0005634; GO:0005654; GO:0005667; GO:0005730; GO:0006260; GO:0006355; GO:0006476; GO:0007568; GO:0008104; GO:0010243; GO:0010817; GO:0010971; GO:0016575; GO:0016580; GO:0017053; GO:0021895; GO:0030336; GO:0030512; GO:0030516; GO:0031453; GO:0032991; GO:0042754; GO:0043066; GO:0043619; GO:0044877; GO:0045666; GO:0045892; GO:0045944; GO:0048511; GO:0051595; GO:0061629; GO:0071333; GO:0140416; GO:1900181; GO:1901675; GO:1902455; GO:1902459; GO:1903351; GO:2000678 32161 XM_029334879.2 13 43 10 7 3 P00377 1.63e-45 Dihydrofolate reductase (EC 1.5.1.3) Sus scrofa (Pig) glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653] GO:0003729; GO:0004146; GO:0005737; GO:0005739; GO:0006545; GO:0006730; GO:0031427; GO:0046653; GO:0046654; GO:0050661 32162 XM_029339290.2 1127 755 703 996 999 Q92556 0 Engulfment and cell motility protein 1 (Protein ced-12 homolog) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; apoptotic process [GO:0006915]; cell motility [GO:0048870]; phagocytosis, engulfment [GO:0006911]; Rac protein signal transduction [GO:0016601] GO:0005737; GO:0005829; GO:0005886; GO:0006911; GO:0006915; GO:0007015; GO:0016020; GO:0016601; GO:0017124; GO:0030036; GO:0032045; GO:0048870 32163 XM_044316213.1 6 0 9 0 4 NA NA NA NA NA NA 32164 XR_006394255.1 11 4 43 9 189 NA NA NA NA NA NA 32165 XM_029347210.2 59 38 112 78 42 A8MT70 1.69e-21 Zinc finger B-box domain-containing protein 1 Homo sapiens (Human) cilium movement [GO:0003341] GO:0003341; GO:0031514; GO:0046872 32166 XM_044319377.1 1 0 30 3 20 NA NA NA NA NA NA 32167 XM_044316189.1 16 1 60 4 88 NA NA NA NA NA NA 32168 XR_003826515.2 0 10 7 0 31 NA NA NA NA NA NA 32169 XM_044314169.1 5 28 78 59 27 NA NA NA NA NA NA 32170 XM_029330133.2 342 147 171 214 350 Q15696 5.62e-79 U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2 (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (Renal carcinoma antigen NY-REN-20) (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (U2AF35-related protein) (URP) Homo sapiens (Human) mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]; spliceosomal complex assembly [GO:0000245] GO:0000245; GO:0000398; GO:0005654; GO:0005681; GO:0005689; GO:0008380; GO:0030628; GO:0042802; GO:0046872; GO:0089701 32171 XM_044322122.1 191 415 22 301 395 Q9EQK7 3.11e-76 Protein-S-isoprenylcysteine O-methyltransferase (EC 2.1.1.100) (Isoprenylcysteine carboxylmethyltransferase) (Prenylated protein carboxyl methyltransferase) (PPMT) (Prenylcysteine carboxyl methyltransferase) (pcCMT) Mus musculus (Mouse) bone mineralization [GO:0030282]; C-terminal protein methylation [GO:0006481]; determination of adult lifespan [GO:0008340]; fibroblast proliferation [GO:0048144]; in utero embryonic development [GO:0001701]; liver development [GO:0001889]; multicellular organism growth [GO:0035264]; neuromuscular process [GO:0050905]; positive regulation of fibroblast proliferation [GO:0048146]; protein localization [GO:0008104]; protein methylation [GO:0006479]; regulation of cellular senescence [GO:2000772]; regulation of protein localization [GO:0032880]; regulation of Ras protein signal transduction [GO:0046578]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethioninamine metabolic process [GO:0046499]; TOR signaling [GO:0031929] GO:0001701; GO:0001889; GO:0004671; GO:0005783; GO:0005789; GO:0006479; GO:0006481; GO:0008104; GO:0008140; GO:0008340; GO:0016020; GO:0030282; GO:0031929; GO:0032880; GO:0035264; GO:0046498; GO:0046499; GO:0046578; GO:0048144; GO:0048146; GO:0050905; GO:2000772 32172 XM_044328486.1 74 39 0 25 6 Q6NU40 0 Chromosome transmission fidelity protein 18 homolog Xenopus laevis (African clawed frog) cell cycle [GO:0007049]; DNA replication [GO:0006260] GO:0003677; GO:0003689; GO:0005524; GO:0005634; GO:0005663; GO:0006260; GO:0007049; GO:0016887 32173 XR_006396390.1 26 31 72 82 73 NA NA NA NA NA NA 32174 XM_029355863.2 23 44 2 39 36 Q6DBY9 1.91e-43 Carbohydrate sulfotransferase 1 (EC 2.8.2.21) (Keratan sulfate Gal-6 sulfotransferase) (KS6ST) (KSGal6ST) (KSST) Danio rerio (Zebrafish) (Brachydanio rerio) carbohydrate metabolic process [GO:0005975]; keratan sulfate metabolic process [GO:0042339]; N-acetylglucosamine metabolic process [GO:0006044]; sulfur compound metabolic process [GO:0006790] GO:0000139; GO:0001517; GO:0005802; GO:0005975; GO:0006044; GO:0006790; GO:0042339; GO:0045130 32175 XM_029325510.2 62 26 27 21 79 NA NA NA NA NA NA 32176 XM_029324485.2 227 654 451 6 53 NA NA NA NA NA NA 32177 XR_006397212.1 0 7 0 5 0 NA NA NA NA NA NA 32178 XM_044322139.1 129 54 16 39 39 NA NA NA NA NA NA 32179 XM_044322054.1 71 0 43 71 36 Q8NCX0 4.56e-86 Coiled-coil domain-containing protein 150 Homo sapiens (Human) NA NA 32180 XM_044327738.1 1645 2749 1666 1825 1533 Q8C0L0 3.64e-50 Thioredoxin-related transmembrane protein 4 (Thioredoxin domain-containing protein 13) Mus musculus (Mouse) NA GO:0005637; GO:0012505; GO:0015036 32181 XR_006395188.1 0 0 14 9 53 NA NA NA NA NA NA 32182 XM_029347966.2 308 424 302 602 413 O70528 9.64e-32 5-hydroxytryptamine receptor 4 (5-HT-4) (5-HT4) (Serotonin receptor 4) Cavia porcellus (Guinea pig) chemical synaptic transmission [GO:0007268]; regulation of appetite [GO:0032098] GO:0004993; GO:0005768; GO:0005886; GO:0007268; GO:0032098; GO:0045202 32183 XM_029324379.2 9 1 7 0 19 NA NA NA NA NA NA 32184 XM_044312188.1 41 1 56 690 646 Q5AXT5 6.21e-31 ATP-dependent DNA helicase PIF1 (EC 3.6.4.12) (DNA repair and recombination helicase PIF1) Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; mitochondrial genome maintenance [GO:0000002]; telomere maintenance [GO:0000723] GO:0000002; GO:0000723; GO:0003677; GO:0005524; GO:0005634; GO:0005657; GO:0005739; GO:0006260; GO:0006281; GO:0006310; GO:0016887; GO:0032508; GO:0043139 32185 XM_029344283.2 584 338 421 275 65 B3DK16 2.37e-75 Polycomb group RING finger protein 5-A Danio rerio (Zebrafish) (Brachydanio rerio) histone H2A-K119 monoubiquitination [GO:0036353]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0006357; GO:0031519; GO:0035102; GO:0036353; GO:0046872 32186 XM_029334871.2 136 56 46 41 59 NA NA NA NA NA NA 32187 XR_006393659.1 1565 2326 1297 1967 1041 NA NA NA NA NA NA 32188 XR_003827165.2 38 9 68 40 295 NA NA NA NA NA NA 32189 XR_006393392.1 7 49 4 45 36 NA NA NA NA NA NA 32190 XM_029335343.2 1405 2146 1740 2977 1204 P61917 1.27e-38 NPC intracellular cholesterol transporter 2 (EPI-1) (Epididymal secretory protein E1) (Niemann Pick type C2 protein homolog) Pan troglodytes (Chimpanzee) cholesterol efflux [GO:0033344]; cholesterol metabolic process [GO:0008203]; cholesterol transport [GO:0030301]; intracellular cholesterol transport [GO:0032367]; sterol transport [GO:0015918] GO:0005615; GO:0005764; GO:0005783; GO:0008203; GO:0015485; GO:0015918; GO:0030301; GO:0032367; GO:0032934; GO:0033344 32191 XM_029332784.2 3258 3506 1936 3118 2421 O35182 6.04e-53 Mothers against decapentaplegic homolog 6 (MAD homolog 6) (Mothers against DPP homolog 6) (Mad homolog 7) (SMAD family member 6) (SMAD 6) (Smad6) Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; BMP signaling pathway [GO:0030509]; cardiac vascular smooth muscle cell development [GO:0060948]; cell differentiation [GO:0030154]; cell-substrate adhesion [GO:0031589]; coronary vasculature development [GO:0060976]; coronary vasculature morphogenesis [GO:0060977]; fat cell differentiation [GO:0045444]; heart valve development [GO:0003170]; immune response [GO:0006955]; mitral valve morphogenesis [GO:0003183]; negative regulation of apoptotic process [GO:0043066]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ossification [GO:0030279]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of pathway-restricted SMAD protein phosphorylation [GO:0060394]; negative regulation of SMAD protein complex assembly [GO:0010991]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of vasoconstriction [GO:0045907]; pulmonary valve morphogenesis [GO:0003184]; response to estrogen [GO:0043627]; response to laminar fluid shear stress [GO:0034616]; response to lipopolysaccharide [GO:0032496]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ureteric bud development [GO:0001657]; vasoconstriction [GO:0042310]; ventricular septum development [GO:0003281]; zygotic specification of dorsal/ventral axis [GO:0007352] GO:0000976; GO:0001657; GO:0003148; GO:0003170; GO:0003180; GO:0003183; GO:0003184; GO:0003281; GO:0003682; GO:0005634; GO:0005654; GO:0005794; GO:0005829; GO:0006955; GO:0007179; GO:0007352; GO:0008285; GO:0009653; GO:0010991; GO:0016604; GO:0030154; GO:0030279; GO:0030509; GO:0030512; GO:0030514; GO:0031589; GO:0031625; GO:0032496; GO:0032991; GO:0034616; GO:0034713; GO:0035904; GO:0042310; GO:0042802; GO:0043066; GO:0043627; GO:0045444; GO:0045668; GO:0045907; GO:0046872; GO:0060394; GO:0060395; GO:0060948; GO:0060976; GO:0060977; GO:0070410; GO:0070411; GO:0070412; GO:0070698; GO:0071144; GO:0140416; GO:1902895 32192 XR_003822997.2 9 2 10 5 20 NA NA NA NA NA NA 32193 XR_003826794.2 0 121 0 13 0 Q90744 8.21e-139 Alpha-N-acetylgalactosaminidase (EC 3.2.1.49) (Alpha-galactosidase B) Gallus gallus (Chicken) glycoside catabolic process [GO:0016139]; lipid metabolic process [GO:0006629]; oligosaccharide metabolic process [GO:0009311] GO:0004557; GO:0005737; GO:0005764; GO:0006629; GO:0008456; GO:0009311; GO:0016139 32194 XR_006394612.1 0 7 0 9 0 NA NA NA NA NA NA 32195 XM_044316864.1 0 0 3 0 6 F7J220 1.21e-30 Scavenger receptor cysteine-rich domain superfamily protein (ApSRCR1) Patiria pectinifera (Starfish) (Asterina pectinifera) innate immune response [GO:0045087]; phagocytosis [GO:0006909] GO:0005044; GO:0006909; GO:0030659; GO:0045087 32196 XM_044316864.1 0 0 3 0 6 F7J220 6.08e-26 Scavenger receptor cysteine-rich domain superfamily protein (ApSRCR1) Patiria pectinifera (Starfish) (Asterina pectinifera) innate immune response [GO:0045087]; phagocytosis [GO:0006909] GO:0005044; GO:0006909; GO:0030659; GO:0045087 32197 XM_044316864.1 0 0 3 0 6 F7J220 2.63e-25 Scavenger receptor cysteine-rich domain superfamily protein (ApSRCR1) Patiria pectinifera (Starfish) (Asterina pectinifera) innate immune response [GO:0045087]; phagocytosis [GO:0006909] GO:0005044; GO:0006909; GO:0030659; GO:0045087 32198 XM_044316864.1 0 0 3 0 6 F7J220 2.76e-23 Scavenger receptor cysteine-rich domain superfamily protein (ApSRCR1) Patiria pectinifera (Starfish) (Asterina pectinifera) innate immune response [GO:0045087]; phagocytosis [GO:0006909] GO:0005044; GO:0006909; GO:0030659; GO:0045087 32199 XM_044316864.1 0 0 3 0 6 F7J220 2.87e-22 Scavenger receptor cysteine-rich domain superfamily protein (ApSRCR1) Patiria pectinifera (Starfish) (Asterina pectinifera) innate immune response [GO:0045087]; phagocytosis [GO:0006909] GO:0005044; GO:0006909; GO:0030659; GO:0045087 32200 XM_029332685.2 30 7 15 39 56 Q9H3H1 2.59e-71 tRNA dimethylallyltransferase (EC 2.5.1.75) (Isopentenyl-diphosphate:tRNA isopentenyltransferase) (IPP transferase) (IPPT) (hGRO1) (tRNA isopentenyltransferase 1) (IPTase) Homo sapiens (Human) mitochondrial tRNA modification [GO:0070900]; tRNA modification [GO:0006400] GO:0003676; GO:0005524; GO:0005739; GO:0005759; GO:0006400; GO:0008270; GO:0052381; GO:0070900 32201 XM_029332685.2 30 7 15 39 56 Q9H3H1 9.78e-43 tRNA dimethylallyltransferase (EC 2.5.1.75) (Isopentenyl-diphosphate:tRNA isopentenyltransferase) (IPP transferase) (IPPT) (hGRO1) (tRNA isopentenyltransferase 1) (IPTase) Homo sapiens (Human) mitochondrial tRNA modification [GO:0070900]; tRNA modification [GO:0006400] GO:0003676; GO:0005524; GO:0005739; GO:0005759; GO:0006400; GO:0008270; GO:0052381; GO:0070900 32202 XM_044329196.1 0 165 0 0 0 NA NA NA NA NA NA 32203 XR_003828371.2 0 6 0 2 0 Q9WUV0 4.44e-118 Origin recognition complex subunit 5 Mus musculus (Mouse) DNA replication [GO:0006260]; DNA replication initiation [GO:0006270]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0000808; GO:0003688; GO:0005524; GO:0005654; GO:0005664; GO:0005829; GO:0006260; GO:0006270; GO:0006275 32204 XM_029355095.2 0 29 0 0 0 NA NA NA NA NA NA 32205 XR_006398020.1 1129 1778 532 1225 476 NA NA NA NA NA NA 32206 XM_029328995.2 92 97 21 164 179 Q8BG58 8.16e-58 Transmembrane prolyl 4-hydroxylase (P4H-TM) (EC 1.14.11.29) (Hypoxia-inducible factor prolyl hydroxylase 4) (HIF-PH4) (HIF-prolyl hydroxylase 4) (HPH-4) Mus musculus (Mouse) peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; regulation of erythrocyte differentiation [GO:0045646] GO:0004656; GO:0005506; GO:0005509; GO:0005783; GO:0005789; GO:0016706; GO:0018401; GO:0031418; GO:0045646 32207 XR_006392913.1 41 2 25 5 151 NA NA NA NA NA NA 32208 XM_029355749.2 32 2 52 71 224 NA NA NA NA NA NA 32209 XM_044316907.1 0 0 0 71 0 NA NA NA NA NA NA 32210 XM_029348107.2 0 0 0 0 137 P47793 2.09e-129 Protein Wnt-4a Danio rerio (Zebrafish) (Brachydanio rerio) canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; cell migration involved in gastrulation [GO:0042074]; embryonic viscerocranium morphogenesis [GO:0048703]; habenula development [GO:0021986]; heart development [GO:0007507]; neuron differentiation [GO:0030182]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of axon extension involved in axon guidance [GO:0048841]; sensory epithelium regeneration [GO:0070654] GO:0005109; GO:0005125; GO:0005615; GO:0007507; GO:0021986; GO:0030182; GO:0042074; GO:0045165; GO:0045893; GO:0048703; GO:0048841; GO:0060070; GO:0070654 32211 XM_044315111.1 38 17 9 48 159 NA NA NA NA NA NA 32212 XM_044306962.1 63 33 19 88 71 B3EX02 5.54e-122 MAM and fibronectin type III domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 32213 XM_044306962.1 63 33 19 88 71 B3EX02 8.74e-118 MAM and fibronectin type III domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 32214 XM_044306962.1 63 33 19 88 71 B3EX02 9.28e-83 MAM and fibronectin type III domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 32215 XM_044306962.1 63 33 19 88 71 B3EX02 3.63e-27 MAM and fibronectin type III domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 32216 XM_044325382.1 67 6 0 153 0 Q9Z351 4.78e-56 Potassium voltage-gated channel subfamily KQT member 2 (KQT-like 2) (Potassium channel subunit alpha KvLQT2) (Voltage-gated potassium channel subunit Kv7.2) Mus musculus (Mouse) potassium ion transmembrane transport [GO:0071805]; regulation of ion transmembrane transport [GO:0034765]; transmission of nerve impulse [GO:0019226] GO:0005244; GO:0005249; GO:0005251; GO:0005516; GO:0005886; GO:0008076; GO:0009986; GO:0016020; GO:0019226; GO:0030506; GO:0032991; GO:0033268; GO:0034765; GO:0043194; GO:0047485; GO:0071805 32217 XM_044316122.1 0 8 0 0 0 NA NA NA NA NA NA 32218 XM_029347280.2 350 290 424 414 402 Q9H777 5.87e-93 Zinc phosphodiesterase ELAC protein 1 (EC 3.1.26.11) (Deleted in Ma29) (ElaC homolog protein 1) (Ribonuclease Z 1) (RNase Z 1) (tRNA 3 endonuclease 1) (tRNase Z 1) Homo sapiens (Human) tRNA 3'-trailer cleavage [GO:0042779] GO:0005634; GO:0005654; GO:0005829; GO:0042779; GO:0042781; GO:0046872 32219 XM_044313116.1 142 121 50 104 106 Q1T765 5.14e-24 Centromere protein N (CENP-N) Gallus gallus (Chicken) chromosome segregation [GO:0007059]; kinetochore assembly [GO:0051382] GO:0000775; GO:0005654; GO:0007059; GO:0051382 32220 XM_044314019.1 18 4 2 1 18 NA NA NA NA NA NA 32221 XR_006391398.1 40 41 51 89 16 NA NA NA NA NA NA 32222 XM_029337206.2 186 0 52 69 66 Q64731 1.75e-40 Forkhead box protein L1 (Forkhead-related protein FKHL11) (Transcription factor FKH-6) Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; heart development [GO:0007507]; Peyer's patch morphogenesis [GO:0061146]; proteoglycan biosynthetic process [GO:0030166]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of Wnt signaling pathway [GO:0030111]; visceral mesoderm-endoderm interaction involved in midgut development [GO:0007495] GO:0000978; GO:0000981; GO:0003677; GO:0003700; GO:0005634; GO:0006355; GO:0006357; GO:0007495; GO:0007507; GO:0009653; GO:0030111; GO:0030154; GO:0030166; GO:0043565; GO:0061146 32223 XM_044313094.1 0 49 0 37 104 NA NA NA NA NA NA 32224 XM_029343126.2 8419 10563 4470 12462 9043 Q92519 1.51e-123 Tribbles homolog 2 (TRB-2) Homo sapiens (Human) negative regulation of fat cell differentiation [GO:0045599]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; regulation of MAP kinase activity [GO:0043405] GO:0004860; GO:0005634; GO:0005737; GO:0005856; GO:0006469; GO:0031434; GO:0031625; GO:0032436; GO:0032693; GO:0043405; GO:0045599; GO:0055106; GO:0061629 32225 XM_029342235.2 303 71 40 321 147 O88898 9.74e-58 Tumor protein 63 (p63) (Transformation-related protein 63) (TP63) (Tumor protein p73-like) (p73L) Mus musculus (Mouse) anatomical structure formation involved in morphogenesis [GO:0048646]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular senescence [GO:0090398]; chromatin remodeling [GO:0006338]; cloacal septation [GO:0060197]; cranial skeletal system development [GO:1904888]; ectoderm and mesoderm interaction [GO:0007499]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; epidermal cell differentiation [GO:0009913]; epidermal cell division [GO:0010481]; epidermis development [GO:0008544]; epithelial cell development [GO:0002064]; epithelial cell differentiation [GO:0030855]; establishment of planar polarity [GO:0001736]; establishment of skin barrier [GO:0061436]; female genitalia morphogenesis [GO:0048807]; hair follicle development [GO:0001942]; hair follicle morphogenesis [GO:0031069]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; keratinocyte differentiation [GO:0030216]; keratinocyte proliferation [GO:0043616]; morphogenesis of a polarized epithelium [GO:0001738]; multicellular organism aging [GO:0010259]; negative regulation of cellular senescence [GO:2000773]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of keratinocyte differentiation [GO:0045617]; negative regulation of mesoderm development [GO:2000381]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron apoptotic process [GO:0051402]; Notch signaling pathway [GO:0007219]; odontogenesis of dentin-containing tooth [GO:0042475]; pattern specification process [GO:0007389]; polarized epithelial cell differentiation [GO:0030859]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cell cycle G1/S phase transition [GO:1902808]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of fibroblast apoptotic process [GO:2000271]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of somatic stem cell population maintenance [GO:1904674]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; prostate gland development [GO:0030850]; prostatic bud formation [GO:0060513]; protein tetramerization [GO:0051262]; proximal/distal pattern formation [GO:0009954]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of epidermal cell division [GO:0010482]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal system development [GO:0001501]; skin epidermis development [GO:0098773]; skin morphogenesis [GO:0043589]; spermatogenesis [GO:0007283]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; stem cell differentiation [GO:0048863]; stem cell proliferation [GO:0072089]; sympathetic nervous system development [GO:0048485]; transcription by RNA polymerase II [GO:0006366] GO:0000122; GO:0000785; GO:0000977; GO:0000978; GO:0000981; GO:0001228; GO:0001501; GO:0001736; GO:0001738; GO:0001942; GO:0002039; GO:0002064; GO:0003677; GO:0003682; GO:0003684; GO:0003690; GO:0003700; GO:0005634; GO:0005654; GO:0005737; GO:0005791; GO:0006338; GO:0006357; GO:0006366; GO:0006915; GO:0006974; GO:0007219; GO:0007283; GO:0007389; GO:0007499; GO:0008284; GO:0008544; GO:0009887; GO:0009913; GO:0009954; GO:0010259; GO:0010481; GO:0010482; GO:0010838; GO:0019904; GO:0030216; GO:0030326; GO:0030425; GO:0030850; GO:0030855; GO:0030859; GO:0031069; GO:0032991; GO:0033147; GO:0035115; GO:0035116; GO:0036342; GO:0042475; GO:0042771; GO:0042802; GO:0043005; GO:0043281; GO:0043565; GO:0043589; GO:0043616; GO:0045617; GO:0045669; GO:0045747; GO:0045892; GO:0045893; GO:0045944; GO:0046872; GO:0048485; GO:0048646; GO:0048807; GO:0048863; GO:0050699; GO:0051262; GO:0051402; GO:0060197; GO:0060513; GO:0060529; GO:0061436; GO:0072089; GO:0090398; GO:0097371; GO:0098773; GO:1902808; GO:1904674; GO:1904888; GO:2000271; GO:2000381; GO:2000648; GO:2000773; GO:2001235 32226 XM_044312053.1 4697 9676 2416 12939 7462 NA NA NA NA NA NA 32227 XM_044319212.1 67 69 42 82 44 P0DX22 3.83e-26 NA NA NA NA 32228 XM_029339798.2 691 196 134 1428 258 NA NA NA NA NA NA 32229 XM_044311878.1 18 20 20 30 44 NA NA NA NA NA NA 32230 XM_029334887.2 310 264 185 310 255 O42574 4.39e-24 Beta-1 adrenergic receptor (Beta-1 adrenoreceptor) (Beta-1 adrenoceptor) (x-BETA1AR) Xenopus laevis (African clawed frog) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; positive regulation of GTPase activity [GO:0043547]; positive regulation of heart contraction [GO:0045823] GO:0004940; GO:0005085; GO:0005769; GO:0005886; GO:0043547; GO:0045823; GO:0071880 32231 XM_029349651.2 11 1 15 16 74 NA NA NA NA NA NA 32232 XM_044317924.1 16899 18210 11323 21286 21400 P08582 1.3e-62 Melanotransferrin (Melanoma-associated antigen p97) (CD antigen CD228) Homo sapiens (Human) iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of plasminogen activation [GO:0010756] GO:0005506; GO:0005576; GO:0005615; GO:0005769; GO:0005788; GO:0005886; GO:0006826; GO:0009986; GO:0010756; GO:0055037; GO:0055072; GO:0070062; GO:0090091; GO:1900025 32233 XM_044317924.1 16899 18210 11323 21286 21400 P08582 8.7e-62 Melanotransferrin (Melanoma-associated antigen p97) (CD antigen CD228) Homo sapiens (Human) iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of plasminogen activation [GO:0010756] GO:0005506; GO:0005576; GO:0005615; GO:0005769; GO:0005788; GO:0005886; GO:0006826; GO:0009986; GO:0010756; GO:0055037; GO:0055072; GO:0070062; GO:0090091; GO:1900025 32234 XM_044328446.1 115 56 38 68 58 NA NA NA NA NA NA 32235 XM_044312772.1 99 57 119 223 62 NA NA NA NA NA NA 32236 XM_044321056.1 662 859 619 915 885 Q58DT4 1.45e-66 Pyrroline-5-carboxylate reductase 1, mitochondrial (P5C reductase 1) (P5CR 1) (EC 1.5.1.2) Bos taurus (Bovine) cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; proline biosynthetic process [GO:0006561] GO:0004735; GO:0005739; GO:0006561; GO:0034599; GO:0055129 32237 XM_044321607.1 1931 422 282 1451 1013 NA NA NA NA NA NA 32238 XM_044311895.1 0 0 7 18 44 NA NA NA NA NA NA 32239 XM_029353987.2 447 465 206 368 340 Q66H07 1.77e-88 Fibronectin type 3 and ankyrin repeat domains 1 protein Rattus norvegicus (Rat) negative regulation of apoptotic process [GO:0043066]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of apoptotic process [GO:0042981] GO:0005634; GO:0005737; GO:0005829; GO:0005929; GO:0036064; GO:0042981; GO:0043065; GO:0043066; GO:0045893; GO:0051091; GO:0097546 32240 XR_006397521.1 32 10 24 142 97 NA NA NA NA NA NA 32241 XR_003825558.2 22 0 2 2 60 NA NA NA NA NA NA 32242 XM_044320137.1 92 28 13 76 67 NA NA NA NA NA NA 32243 XM_029334066.2 95 85 317 57 375 Q9NTG7 7.39e-121 NAD-dependent protein deacetylase sirtuin-3, mitochondrial (hSIRT3) (EC 2.3.1.286) (Regulatory protein SIR2 homolog 3) (SIR2-like protein 3) Homo sapiens (Human) aerobic respiration [GO:0009060]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of catalase activity [GO:1902553]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of superoxide dismutase activity [GO:1901671]; protein deacetylation [GO:0006476] GO:0005634; GO:0005654; GO:0005739; GO:0005759; GO:0006476; GO:0008270; GO:0009060; GO:0016740; GO:0017136; GO:0032991; GO:0034979; GO:0034983; GO:0043565; GO:0070403; GO:1901671; GO:1902553; GO:2000304 32244 XM_044313905.1 0 0 0 0 7 Q09575 8.76e-40 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 32245 XM_044324864.1 4607 5573 4665 7335 7279 P02463 8.23e-103 Collagen alpha-1(IV) chain [Cleaved into: Arresten] Mus musculus (Mouse) basement membrane organization [GO:0071711]; blood vessel morphogenesis [GO:0048514]; brain development [GO:0007420]; branching involved in blood vessel morphogenesis [GO:0001569]; cellular response to amino acid stimulus [GO:0071230]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; epithelial cell differentiation [GO:0030855]; extracellular matrix organization [GO:0030198]; neuromuscular junction development [GO:0007528]; renal tubule morphogenesis [GO:0061333]; retinal blood vessel morphogenesis [GO:0061304] GO:0001569; GO:0005201; GO:0005576; GO:0005587; GO:0005604; GO:0005615; GO:0007420; GO:0007528; GO:0030020; GO:0030198; GO:0030855; GO:0031012; GO:0038063; GO:0048407; GO:0048514; GO:0061304; GO:0061333; GO:0062023; GO:0071230; GO:0071711 32246 XM_044324864.1 4607 5573 4665 7335 7279 P02463 5.77e-21 Collagen alpha-1(IV) chain [Cleaved into: Arresten] Mus musculus (Mouse) basement membrane organization [GO:0071711]; blood vessel morphogenesis [GO:0048514]; brain development [GO:0007420]; branching involved in blood vessel morphogenesis [GO:0001569]; cellular response to amino acid stimulus [GO:0071230]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; epithelial cell differentiation [GO:0030855]; extracellular matrix organization [GO:0030198]; neuromuscular junction development [GO:0007528]; renal tubule morphogenesis [GO:0061333]; retinal blood vessel morphogenesis [GO:0061304] GO:0001569; GO:0005201; GO:0005576; GO:0005587; GO:0005604; GO:0005615; GO:0007420; GO:0007528; GO:0030020; GO:0030198; GO:0030855; GO:0031012; GO:0038063; GO:0048407; GO:0048514; GO:0061304; GO:0061333; GO:0062023; GO:0071230; GO:0071711 32247 XM_044311413.1 11 0 7 42 36 O60290 1.24e-49 Zinc finger protein 862 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006355; GO:0046872; GO:0046983 32248 XM_044313670.1 720 541 283 352 1 NA NA NA NA NA NA 32249 XM_029349690.2 647 708 310 487 491 F1QMV3 6.13e-67 Trafficking protein particle complex subunit 6b (TRAPP complex subunit 6B) Danio rerio (Zebrafish) (Brachydanio rerio) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; nervous system development [GO:0007399]; regulation of GTPase activity [GO:0043087] GO:0005783; GO:0005801; GO:0005802; GO:0006888; GO:0007399; GO:0030008; GO:0043087 32250 XM_029339468.2 403 239 340 757 789 P51612 9.51e-114 DNA repair protein complementing XP-C cells homolog (Xeroderma pigmentosum group C-complementing protein homolog) (p125) Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]; mitotic intra-S DNA damage checkpoint signaling [GO:0031573]; nucleotide-excision repair [GO:0006289]; positive regulation of DNA-templated transcription [GO:0045893]; pyrimidine dimer repair by nucleotide-excision repair [GO:0000720]; regulation of gluconeogenesis [GO:0006111]; regulation of mitotic cell cycle phase transition [GO:1901990]; response to auditory stimulus [GO:0010996]; response to UV-B [GO:0010224]; response to xenobiotic stimulus [GO:0009410]; UV-damage excision repair [GO:0070914] GO:0000109; GO:0000111; GO:0000720; GO:0003684; GO:0003697; GO:0003713; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005739; GO:0005829; GO:0005886; GO:0006111; GO:0006281; GO:0006289; GO:0006298; GO:0006974; GO:0009410; GO:0010224; GO:0010996; GO:0031573; GO:0043231; GO:0044877; GO:0045893; GO:0061629; GO:0070914; GO:0071942; GO:0090734; GO:0140612; GO:1901990 32251 XM_044317816.1 237 176 183 242 244 Q8HYJ7 2.05e-43 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5 (EC 2.4.1.152) (3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT5) (EC 2.4.1.65) (Fucosyltransferase 5) (Fucosyltransferase V) (Fuc-TV) (FucT-V) (Galactoside 3-L-fucosyltransferase) Gorilla gorilla gorilla (Western lowland gorilla) ceramide metabolic process [GO:0006672]; fucosylation [GO:0036065]; oligosaccharide metabolic process [GO:0009311]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493] GO:0006487; GO:0006493; GO:0006672; GO:0009311; GO:0017060; GO:0017083; GO:0032580; GO:0036065; GO:0046920 32252 XM_029341538.2 37 10 18 0 12 Q8IN35 6.19e-33 Neuropeptide SIFamide receptor Drosophila melanogaster (Fruit fly) determination of adult lifespan [GO:0008340]; G protein-coupled receptor signaling pathway [GO:0007186]; mating behavior, sex discrimination [GO:0048047]; neuropeptide signaling pathway [GO:0007218] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0008340; GO:0008528; GO:0016020; GO:0042277; GO:0048047 32253 XM_044325896.1 0 0 18 0 0 NA NA NA NA NA NA 32254 XM_044312520.1 0 38 113 120 100 Q02356 0 AMP deaminase 2 (EC 3.5.4.6) (AMP deaminase isoform L) Rattus norvegicus (Rat) AMP metabolic process [GO:0046033]; ATP metabolic process [GO:0046034]; cholesterol homeostasis [GO:0042632]; cyclic purine nucleotide metabolic process [GO:0052652]; energy homeostasis [GO:0097009]; GTP metabolic process [GO:0046039]; IMP biosynthetic process [GO:0006188]; IMP salvage [GO:0032264]; nucleotide metabolic process [GO:0009117]; podocyte development [GO:0072015] GO:0003876; GO:0005829; GO:0006188; GO:0009117; GO:0032264; GO:0042632; GO:0046033; GO:0046034; GO:0046039; GO:0046872; GO:0052652; GO:0072015; GO:0097009 32255 XM_044320072.1 18361 10905 10383 14408 10028 Q5IZC5 1.53e-166 Cryptochrome-1 Erithacus rubecula (European robin) circadian rhythm [GO:0007623]; negative regulation of gluconeogenesis [GO:0045721]; response to light stimulus [GO:0009416] GO:0000166; GO:0003677; GO:0005634; GO:0005829; GO:0007623; GO:0009416; GO:0009881; GO:0042622; GO:0045721; GO:0097381 32256 XM_044320072.1 18361 10905 10383 14408 10028 Q5IZC5 8.14e-154 Cryptochrome-1 Erithacus rubecula (European robin) circadian rhythm [GO:0007623]; negative regulation of gluconeogenesis [GO:0045721]; response to light stimulus [GO:0009416] GO:0000166; GO:0003677; GO:0005634; GO:0005829; GO:0007623; GO:0009416; GO:0009881; GO:0042622; GO:0045721; GO:0097381 32257 XM_044320072.1 18361 10905 10383 14408 10028 Q5IZC5 1.54e-150 Cryptochrome-1 Erithacus rubecula (European robin) circadian rhythm [GO:0007623]; negative regulation of gluconeogenesis [GO:0045721]; response to light stimulus [GO:0009416] GO:0000166; GO:0003677; GO:0005634; GO:0005829; GO:0007623; GO:0009416; GO:0009881; GO:0042622; GO:0045721; GO:0097381 32258 XM_044320072.1 18361 10905 10383 14408 10028 Q5IZC5 3.84e-149 Cryptochrome-1 Erithacus rubecula (European robin) circadian rhythm [GO:0007623]; negative regulation of gluconeogenesis [GO:0045721]; response to light stimulus [GO:0009416] GO:0000166; GO:0003677; GO:0005634; GO:0005829; GO:0007623; GO:0009416; GO:0009881; GO:0042622; GO:0045721; GO:0097381 32259 XM_044320072.1 18361 10905 10383 14408 10028 Q5IZC5 1.3e-128 Cryptochrome-1 Erithacus rubecula (European robin) circadian rhythm [GO:0007623]; negative regulation of gluconeogenesis [GO:0045721]; response to light stimulus [GO:0009416] GO:0000166; GO:0003677; GO:0005634; GO:0005829; GO:0007623; GO:0009416; GO:0009881; GO:0042622; GO:0045721; GO:0097381 32260 XM_044309860.1 1392 491 232 541 764 NA NA NA NA NA NA 32261 XM_044317862.1 0 1 0 0 23 NA NA NA NA NA NA 32262 XR_006391653.1 31 7 28 34 14 Q570Y9 4.35e-42 DEP domain-containing mTOR-interacting protein (DEP domain-containing protein 6) Mus musculus (Mouse) intracellular signal transduction [GO:0035556]; negative regulation of cell size [GO:0045792]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of TOR signaling [GO:0032007]; negative regulation of TORC1 signaling [GO:1904262]; negative regulation of TORC2 signaling [GO:1903940]; regulation of extrinsic apoptotic signaling pathway [GO:2001236] GO:0006469; GO:0032007; GO:0035556; GO:0045792; GO:1903940; GO:1904262; GO:2001236 32263 XM_044323015.1 295 187 189 119 22 Q5XJ85 4.48e-27 Myeloid differentiation primary response protein MyD88 Danio rerio (Zebrafish) (Brachydanio rerio) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; monocyte activation [GO:0042117]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; neutrophil activation involved in immune response [GO:0002283]; neutrophil chemotaxis [GO:0030593]; positive regulation of hematopoietic progenitor cell differentiation [GO:1901534]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of hematopoietic progenitor cell differentiation [GO:1901532]; response to molecule of bacterial origin [GO:0002237]; Toll signaling pathway [GO:0008063] GO:0002218; GO:0002237; GO:0002283; GO:0002755; GO:0005737; GO:0005886; GO:0006954; GO:0008063; GO:0030593; GO:0035325; GO:0042117; GO:0042742; GO:0043123; GO:0045087; GO:0050830; GO:0070976; GO:1901532; GO:1901534 32264 XM_044321246.1 158 147 87 139 159 F6QEU4 8.95e-49 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 32265 XR_006392451.1 31 1 0 26 0 Q99570 4.72e-22 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 32266 XR_006394972.1 0 0 0 0 11 NA NA NA NA NA NA 32267 XM_029338470.2 814 757 495 728 714 P29674 4.76e-90 LIM/homeobox protein Lhx1 (LIM homeobox protein 1) (Homeobox protein Lim-1) (Xlim1) (x-Lhx1) (xLIM-1) Xenopus laevis (African clawed frog) anterior/posterior pattern specification [GO:0009952]; axis specification [GO:0009798]; cell migration involved in gastrulation [GO:0042074]; chordate embryonic development [GO:0043009]; muscle organ development [GO:0007517]; nephron tubule development [GO:0072080]; neurogenesis [GO:0022008]; notochord development [GO:0030903]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; pronephric field specification [GO:0039003]; pronephric nephron tubule development [GO:0039020]; pronephros development [GO:0048793]; regionalization [GO:0003002]; regulation of pronephros size [GO:0035565]; response to retinoic acid [GO:0032526] GO:0000981; GO:0001221; GO:0003002; GO:0005634; GO:0005667; GO:0007517; GO:0009798; GO:0009952; GO:0022008; GO:0030903; GO:0032526; GO:0035565; GO:0039003; GO:0039020; GO:0042074; GO:0043009; GO:0043565; GO:0045893; GO:0045944; GO:0046872; GO:0048793; GO:0072080 32268 XM_044307666.1 0 21 0 125 90 NA NA NA NA NA NA 32269 XM_029326995.2 61835 32206 27456 54787 38838 NA NA NA NA NA NA 32270 XM_029336014.2 533 406 293 535 510 Q6ZW76 1.7e-44 Ankyrin repeat and SAM domain-containing protein 3 Homo sapiens (Human) NA GO:0005737; GO:0005929 32271 XM_029342704.2 623 309 279 602 621 Q15526 1.89e-77 Surfeit locus protein 1 Homo sapiens (Human) aerobic respiration [GO:0009060]; mitochondrial cytochrome c oxidase assembly [GO:0033617]; respiratory chain complex IV assembly [GO:0008535] GO:0004129; GO:0005739; GO:0005746; GO:0008535; GO:0009060; GO:0033617 32272 XR_006397658.1 22 0 8 0 14 A0A8V1ABE9 8.48e-122 NA NA NA NA 32273 XM_044309009.1 0 27 0 60 247 NA NA NA NA NA NA 32274 XR_006396234.1 80 72 8 76 285 NA NA NA NA NA NA 32275 XM_029333469.2 0 0 0 0 6 NA NA NA NA NA NA 32276 XM_029328964.2 2564 2658 1925 3692 3479 P57784 4.58e-77 U2 small nuclear ribonucleoprotein A' (U2 snRNP A') Mus musculus (Mouse) mRNA splicing, via spliceosome [GO:0000398]; spermatogenesis [GO:0007283] GO:0000398; GO:0005634; GO:0005654; GO:0005681; GO:0005686; GO:0007283; GO:0016604; GO:0016607; GO:0030620; GO:0071005; GO:0071007; GO:0071013 32277 XM_044308784.1 249 610 314 469 312 NA NA NA NA NA NA 32278 XM_029356330.2 3737 4214 1805 3430 2412 Q5EBG8 2.26e-60 Uncharacterized protein C1orf50 homolog Mus musculus (Mouse) NA GO:0042802 32279 XM_029340789.2 228 72 89 110 61 Q8K2J9 6.76e-56 BTB/POZ domain-containing protein 6 Mus musculus (Mouse) neurogenesis [GO:0022008] GO:0005829; GO:0022008 32280 XM_029339314.2 93 29 27 68 64 Q9GLP1 1.74e-26 Coagulation factor V (Activated protein C cofactor) [Cleaved into: Coagulation factor V heavy chain; Coagulation factor V light chain] Sus scrofa (Pig) blood circulation [GO:0008015]; blood coagulation [GO:0007596] GO:0005507; GO:0005576; GO:0007596; GO:0008015; GO:0031091 32281 XR_006397248.1 143 25 0 0 49 NA NA NA NA NA NA 32282 XM_044326568.1 13 49 29 37 50 NA NA NA NA NA NA 32283 XM_029339937.2 5564 7557 4698 9449 7824 Q5IGR8 0 Exostosin-1a (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase 1a) (Multiple exostoses protein 1 homolog a) Danio rerio (Zebrafish) (Brachydanio rerio) heparan sulfate proteoglycan biosynthetic process [GO:0015012]; protein glycosylation [GO:0006486] GO:0005789; GO:0005794; GO:0006486; GO:0008375; GO:0015012; GO:0015020; GO:0016757; GO:0046872; GO:0050508; GO:0050509 32284 XM_029331855.2 610 377 347 892 1517 O08653 1.16e-39 Telomerase protein component 1 (rTLP1) (Telomerase-associated protein 1) (Telomerase protein 1) (p230) (p240) (p80 telomerase homolog) Rattus norvegicus (Rat) RNA-templated DNA biosynthetic process [GO:0006278]; telomere maintenance via recombination [GO:0000722] GO:0000722; GO:0000781; GO:0002039; GO:0003723; GO:0005524; GO:0005697; GO:0005737; GO:0006278; GO:0016363; GO:0019899; GO:0070034; GO:1990904 32285 XM_029329122.2 2109 3098 1873 1702 1958 Q99622 1.51e-23 Protein C10 Homo sapiens (Human) camera-type eye morphogenesis [GO:0048593]; cognition [GO:0050890]; corpus callosum morphogenesis [GO:0021540]; post-embryonic development [GO:0009791]; psychomotor behavior [GO:0036343]; regulation of skeletal muscle contraction [GO:0014819]; third ventricle development [GO:0021678] GO:0005737; GO:0009791; GO:0014819; GO:0016607; GO:0021540; GO:0021678; GO:0036343; GO:0048593; GO:0050890 32286 XR_006393360.1 0 0 0 0 21 NA NA NA NA NA NA 32287 XM_044315343.1 23 43 5 28 56 NA NA NA NA NA NA 32288 XM_044325600.1 10 0 9 0 5 NA NA NA NA NA NA 32289 XM_044318632.1 731 614 289 4 85 Q9Z2E3 1.84e-54 Serine/threonine-protein kinase/endoribonuclease IRE2 (Endoplasmic reticulum-to-nucleus signaling 2) (Inositol-requiring protein 2) (Ire1-beta) (IRE1b) (mIre1) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)] Mus musculus (Mouse) apoptotic chromosome condensation [GO:0030263]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; IRE1-mediated unfolded protein response [GO:0036498]; mRNA processing [GO:0006397]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of JUN kinase activity [GO:0043507]; protein phosphorylation [GO:0006468]; regulation of DNA-templated transcription [GO:0006355]; response to endoplasmic reticulum stress [GO:0034976]; rRNA catabolic process [GO:0016075] GO:0000287; GO:0004519; GO:0004521; GO:0004674; GO:0005524; GO:0005783; GO:0005829; GO:0006355; GO:0006397; GO:0006468; GO:0016075; GO:0030263; GO:0034976; GO:0036498; GO:0043507; GO:0044322; GO:0045892; GO:0051082; GO:0070059; GO:0106310; GO:1990604 32290 XR_006394092.1 100 0 0 0 0 NA NA NA NA NA NA 32291 XM_029357505.2 0 2 8 0 0 P23824 2.65e-70 GATA-binding factor 2 (GATA-2) (Transcription factor NF-E1b) Gallus gallus (Chicken) cell fate commitment [GO:0045165]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of angiogenesis [GO:0045766]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000122; GO:0000978; GO:0000981; GO:0001223; GO:0005634; GO:0008270; GO:0045165; GO:0045766; GO:0045944; GO:1902895 32292 XM_029328917.2 21 19 48 83 73 P24045 1.77e-60 Gamma-aminobutyric acid receptor subunit beta-4 (GABA(A) receptor subunit beta-4) Gallus gallus (Chicken) chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165] GO:0004890; GO:0005231; GO:0005254; GO:0005886; GO:0007165; GO:0007268; GO:0030594; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:1902476; GO:1902711; GO:1904315 32293 XM_029351358.2 237 37 50 110 17 NA NA NA NA NA NA 32294 XM_029328986.2 475 343 226 337 394 NA NA NA NA NA NA 32295 XR_006398003.1 201 84 84 223 158 NA NA NA NA NA NA 32296 XM_029356753.2 0 0 0 68 0 Q8NHP1 3.6e-87 Aflatoxin B1 aldehyde reductase member 4 (EC 1.-.-.-) (AFB1 aldehyde reductase 3) (AFB1-AR 3) (Aldoketoreductase 7-like) Homo sapiens (Human) NA GO:0004033; GO:0005737; GO:0005829; GO:0070062 32297 XM_029356753.2 0 0 0 68 0 Q8NHP1 5.66e-60 Aflatoxin B1 aldehyde reductase member 4 (EC 1.-.-.-) (AFB1 aldehyde reductase 3) (AFB1-AR 3) (Aldoketoreductase 7-like) Homo sapiens (Human) NA GO:0004033; GO:0005737; GO:0005829; GO:0070062 32298 XM_044311815.1 41 7 8 2 73 Q96AY4 2.36e-94 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32299 XM_044311815.1 41 7 8 2 73 Q96AY4 3.74e-91 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32300 XM_044311815.1 41 7 8 2 73 Q96AY4 1.47e-88 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32301 XM_044311815.1 41 7 8 2 73 Q96AY4 8.27e-84 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32302 XM_044311815.1 41 7 8 2 73 Q96AY4 4.7e-83 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32303 XM_044311815.1 41 7 8 2 73 Q96AY4 8.92e-82 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32304 XM_044311815.1 41 7 8 2 73 Q96AY4 3.3e-73 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32305 XM_044311815.1 41 7 8 2 73 Q96AY4 8.71e-56 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32306 XM_044311815.1 41 7 8 2 73 Q96AY4 1.93e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32307 XM_044311815.1 41 7 8 2 73 Q96AY4 2.5e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32308 XM_029329533.2 622 258 191 503 247 Q5F349 1.51e-54 Protein O-mannose kinase (POMK) (EC 2.7.1.183) (Protein kinase-like protein SgK196) (Sugen kinase 196) Gallus gallus (Chicken) carbohydrate phosphorylation [GO:0046835]; protein O-linked glycosylation [GO:0006493]; protein phosphorylation [GO:0006468] GO:0004672; GO:0005524; GO:0005789; GO:0006468; GO:0006493; GO:0016773; GO:0019200; GO:0046835 32309 XM_029347094.2 5 3 2 4 11 Q09575 2.56e-40 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 32310 XM_029350606.2 1089 742 470 858 901 Q5F3F5 1.28e-170 G-protein coupled receptor-associated protein LMBRD2 Gallus gallus (Chicken) adrenergic receptor signaling pathway [GO:0071875] GO:0005886; GO:0016020; GO:0071875 32311 XM_029324220.2 0 143 19 0 0 P0DXC0 1.16e-108 NA NA NA NA 32312 XM_044328696.1 322 136 99 195 237 Q3T075 1.52e-36 Syntaxin-8 Bos taurus (Bovine) intracellular protein transport [GO:0006886]; vesicle docking [GO:0048278]; vesicle fusion [GO:0006906] GO:0000149; GO:0005484; GO:0006886; GO:0006906; GO:0012505; GO:0016020; GO:0031201; GO:0048278 32313 XM_029336911.2 0 81 319 162 162 Q765P7 7.98e-59 Protein MTSS 2 (Actin-bundling with BAIAP2 homology protein 1) (ABBA-1) (MTSS1-like protein) Homo sapiens (Human) activation of GTPase activity [GO:0090630]; cell projection assembly [GO:0030031]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; lamellipodium organization [GO:0097581]; membrane organization [GO:0061024]; plasma membrane organization [GO:0007009] GO:0003779; GO:0003785; GO:0005096; GO:0005543; GO:0005546; GO:0007009; GO:0009898; GO:0015629; GO:0030027; GO:0030031; GO:0030864; GO:0031267; GO:0032587; GO:0036120; GO:0061024; GO:0090630; GO:0097581 32314 XR_006396232.1 302 205 99 192 139 NA NA NA NA NA NA 32315 XM_044323264.1 159 30 100 143 83 NA NA NA NA NA NA 32316 XM_044311709.1 1448 1142 693 851 838 B1WAP7 0 Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) ciliary basal body organization [GO:0032053]; cilium assembly [GO:0060271]; intracellular signal transduction [GO:0035556]; Wnt signaling pathway [GO:0016055] GO:0005737; GO:0008013; GO:0016055; GO:0032053; GO:0035556; GO:0060271 32317 XM_029356570.2 4623 5815 3057 4270 2833 Q9VJ33 9.63e-31 NEDD8 (Neddylin) (Ubiquitin-like protein Nedd8) Drosophila melanogaster (Fruit fly) cell population proliferation [GO:0008283]; female germ-line stem cell population maintenance [GO:0036099]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of smoothened signaling pathway [GO:0045879]; protein neddylation [GO:0045116]; regulation of protein stability [GO:0031647]; regulation of proteolysis [GO:0030162]; regulation of smoothened signaling pathway [GO:0008589]; regulation of stem cell differentiation [GO:2000736]; regulation of ubiquitin-protein transferase activity [GO:0051438]; sleep [GO:0030431] GO:0005634; GO:0005737; GO:0008283; GO:0008589; GO:0019941; GO:0030162; GO:0030431; GO:0031386; GO:0031625; GO:0031647; GO:0036099; GO:0045116; GO:0045879; GO:0051438; GO:2000736 32318 XR_006391708.1 534 407 304 658 487 NA NA NA NA NA NA 32319 XM_029349949.2 303 144 97 223 351 Q6GLK6 3.7e-180 Malonate--CoA ligase ACSF3, mitochondrial (EC 6.2.1.76) (Acyl-CoA synthetase family member 3) Xenopus laevis (African clawed frog) fatty acid metabolic process [GO:0006631] GO:0005524; GO:0005739; GO:0006631; GO:0090409 32320 XM_029345214.2 73 19 23 19 38 NA NA NA NA NA NA 32321 XM_044327061.1 120 18 25 152 145 NA NA NA NA NA NA 32322 XM_044314687.1 0 14 0 5 39 Q8NDX2 3.22e-107 Vesicular glutamate transporter 3 (VGluT3) (Solute carrier family 17 member 8) Homo sapiens (Human) anion transport [GO:0006820]; brain development [GO:0007420]; cochlea development [GO:0090102]; ion transport [GO:0006811]; L-glutamate import [GO:0051938]; L-glutamate transmembrane transport [GO:0015813]; neural retina development [GO:0003407]; neurotransmitter loading into synaptic vesicle [GO:0098700]; phosphate ion homeostasis [GO:0055062]; positive regulation of glutamate uptake involved in transmission of nerve impulse [GO:0051951]; regulation of acetylcholine uptake [GO:0051631]; regulation of synapse structure or activity [GO:0050803]; sensory perception of sound [GO:0007605]; sodium-dependent phosphate transport [GO:0044341]; synaptic transmission, glutamatergic [GO:0035249] GO:0003407; GO:0005254; GO:0005313; GO:0005326; GO:0005436; GO:0005771; GO:0005886; GO:0006811; GO:0006820; GO:0007420; GO:0007605; GO:0015813; GO:0016020; GO:0022857; GO:0030672; GO:0034707; GO:0035249; GO:0043204; GO:0043679; GO:0044341; GO:0050803; GO:0051631; GO:0051938; GO:0051951; GO:0055062; GO:0060076; GO:0090102; GO:0097440; GO:0097441; GO:0097451; GO:0098700; GO:0140788; GO:1990030 32323 XM_044310159.1 0 26 6 39 22 NA NA NA NA NA NA 32324 XR_006394145.1 158 47 92 148 380 NA NA NA NA NA NA 32325 XR_003826581.2 610 17 360 21 8 NA NA NA NA NA NA 32326 XM_029344035.2 301 194 166 385 442 Q99P31 3.97e-47 Hsp70-binding protein 1 (HspBP1) (Heat shock protein-binding protein 1) (Hsp70-interacting protein 1) Mus musculus (Mouse) positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398] GO:0000774; GO:0031398; GO:0031625; GO:0032436 32327 XM_044329046.1 16 24 9 26 0 Q7Z442 7.03e-63 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Homo sapiens (Human) detection of mechanical stimulus [GO:0050982] GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 32328 XR_006394954.1 19 1 13 16 66 NA NA NA NA NA NA 32329 XM_029349194.2 3 8 12 37 15 NA NA NA NA NA NA 32330 XM_044328088.1 539 0 28 0 191 Q6NZF1 1.67e-29 Zinc finger CCCH domain-containing protein 11A Mus musculus (Mouse) poly(A)+ mRNA export from nucleus [GO:0016973] GO:0000346; GO:0003729; GO:0016973; GO:0046872 32331 XM_044315531.1 14 2 22 6 13 Q2HJ10 1.77e-105 Proton-coupled zinc antiporter SLC30A2 (Solute carrier family 30 member 2) (Zinc transporter 2) (ZnT-2) Mus musculus (Mouse) cellular zinc ion homeostasis [GO:0006882]; positive regulation of sequestering of zinc ion [GO:0061090]; regulation of sequestering of zinc ion [GO:0061088]; response to zinc ion [GO:0010043]; zinc export across plasma membrane [GO:0140882]; zinc ion import into lysosome [GO:0140916]; zinc ion import into mitochondrion [GO:0140917]; zinc ion import into organelle [GO:0062111]; zinc ion import into zymogen granule [GO:0140915]; zinc ion transmembrane transport [GO:0071577]; zinc ion transport [GO:0006829] GO:0005385; GO:0005737; GO:0005743; GO:0005765; GO:0005770; GO:0005886; GO:0006829; GO:0006882; GO:0010008; GO:0010043; GO:0030658; GO:0031410; GO:0042589; GO:0042802; GO:0043231; GO:0046872; GO:0061088; GO:0061090; GO:0062111; GO:0071577; GO:0099503; GO:0140826; GO:0140882; GO:0140915; GO:0140916; GO:0140917 32332 XM_044329262.1 33 5595 480 1255 1404 NA NA NA NA NA NA 32333 XR_006395043.1 723 572 408 606 1034 Q5BJL5 0 Protein strawberry notch homolog 1 Rattus norvegicus (Rat) regulation of DNA-templated transcription [GO:0006355]; regulation of response to stimulus [GO:0048583] GO:0005634; GO:0006355; GO:0031490; GO:0042393; GO:0048583 32334 XM_044320165.1 179 54 36 133 109 A4FUB8 9.95e-75 Transmembrane protein 115 Bos taurus (Bovine) retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] GO:0006890; GO:0032580; GO:0042802 32335 XR_003825036.2 4 3 7 0 3 NA NA NA NA NA NA 32336 XM_029336806.2 32 5 0 0 15 P43690 0 Developmentally-regulated GTP-binding protein 1 (DRG-1) (xDRG) (Translation factor GTPase DRG1) (TRAFAC GTPase DRG1) (EC 3.6.5.-) Xenopus laevis (African clawed frog) microtubule bundle formation [GO:0001578]; positive regulation of microtubule polymerization [GO:0031116] GO:0001578; GO:0003924; GO:0005525; GO:0005634; GO:0005737; GO:0008017; GO:0031116; GO:0046872 32337 XM_029355358.2 1072 2045 623 774 887 NA NA NA NA NA NA 32338 XM_029327578.2 391 125 0 29 0 B8EIZ7 1.91e-168 NA NA NA NA 32339 XM_029351218.2 0 1 13 0 0 NA NA NA NA NA NA 32340 XM_029338775.2 101 81 121 56 186 NA NA NA NA NA NA 32341 XM_029345854.2 6 4 4 0 3 NA NA NA NA NA NA 32342 XM_029329735.2 449 297 202 330 314 NA NA NA NA NA NA 32343 XM_029329446.2 70 77 37 51 74 Q8BHR2 3.41e-33 Ecto-NOX disulfide-thiol exchanger 1 (Constitutive Ecto-NOX) (cNOX) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)] Mus musculus (Mouse) ultradian rhythm [GO:0007624] GO:0003723; GO:0003756; GO:0003954; GO:0005615; GO:0005886; GO:0007624; GO:0009897 32344 XM_029339331.2 9 0 0 0 0 NA NA NA NA NA NA 32345 XM_044321863.1 1466 2370 465 112 212 Q5DU56 1.7e-24 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 32346 XM_029327722.2 192 7 36 29 400 NA NA NA NA NA NA 32347 XM_044328819.1 0 1 7 0 0 NA NA NA NA NA NA 32348 XR_003825324.2 21 0 0 0 0 NA NA NA NA NA NA 32349 XM_029348501.2 4 6 6 0 0 NA NA NA NA NA NA 32350 XR_006391737.1 12 0 0 8 17 Q96DM1 1.39e-43 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 32351 XR_006393911.1 41 2 25 5 151 NA NA NA NA NA NA 32352 XM_044308297.1 0 50 0 106 0 NA NA NA NA NA NA 32353 XM_044327133.1 0 0 0 0 89 NA NA NA NA NA NA 32354 XM_029338572.2 43 124 80 21 14 NA NA NA NA NA NA 32355 XM_029335135.2 100 28 96 138 280 NA NA NA NA NA NA 32356 XM_029329636.2 1429 1651 910 1050 1271 Q9QY36 6.67e-98 N-alpha-acetyltransferase 10 (EC 2.3.1.255) (N-terminal acetyltransferase complex ARD1 subunit homolog A) (NatA catalytic subunit Naa10) Mus musculus (Mouse) N-terminal protein amino acid acetylation [GO:0006474]; negative regulation of maintenance of mitotic sister chromatid cohesion, centromeric [GO:2000719]; protein acetylation [GO:0006473] GO:0004596; GO:0005634; GO:0005730; GO:0005737; GO:0005829; GO:0006473; GO:0006474; GO:0008080; GO:0016407; GO:0031415; GO:0043022; GO:1990189; GO:1990190; GO:2000719 32357 XM_044316329.1 142 48 42 323 304 Q09575 2.14e-34 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 32358 XM_044323169.1 0 0 0 0 18 NA NA NA NA NA NA 32359 XM_044311360.1 5 0 0 0 11 NA NA NA NA NA NA 32360 XM_044322263.1 232 40 107 309 176 NA NA NA NA NA NA 32361 XM_029346497.2 1308 1179 675 1221 750 Q8AVY1 2.11e-79 Outer dense fiber protein 3 (Outer dense fiber of sperm tails protein 3) Xenopus laevis (African clawed frog) NA GO:0005737 32362 XM_029332019.2 8 40 28 11 18 Q4R642 2.91e-23 Dynein regulatory complex subunit 5 (T-complex-associated testis-expressed protein 1) (Tcte-1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) flagellated sperm motility [GO:0030317] GO:0005737; GO:0005856; GO:0030317; GO:0036126 32363 XM_029331872.2 132 127 87 331 237 A0A8M1NHK4 1.07e-127 RNA-binding protein 47 (RNA-binding motif protein 47) Danio rerio (Zebrafish) (Brachydanio rerio) antiviral innate immune response [GO:0140374]; lysosomal protein catabolic process [GO:1905146] GO:0003723; GO:0005634; GO:0005764; GO:0140374; GO:1905146 32364 XM_044326820.1 0 0 5 2 8 NA NA NA NA NA NA 32365 XM_029345843.2 2086 1121 1030 2415 2270 Q9M2G7 2.59e-21 Lipid phosphate phosphatase delta (AtLPPD) (EC 3.1.3.-) (Phosphatidic acid phosphatase delta) (Sphingoid phosphate phosphatase 1) (AtSSP1) (Sphingosine-1-phosphate phosphatase) (AtSPPASE) Arabidopsis thaliana (Mouse-ear cress) phospholipid dephosphorylation [GO:0046839]; response to abscisic acid [GO:0009737]; sphingolipid metabolic process [GO:0006665]; stomatal closure [GO:0090332] GO:0005789; GO:0006665; GO:0008117; GO:0009737; GO:0016020; GO:0042392; GO:0046839; GO:0090332 32366 XM_029358234.2 323 258 126 275 806 P14543 2.88e-87 Nidogen-1 (NID-1) (Entactin) Homo sapiens (Human) basement membrane organization [GO:0071711]; cell-matrix adhesion [GO:0007160]; glomerular basement membrane development [GO:0032836]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of muscle cell differentiation [GO:0051149]; regulation of basement membrane organization [GO:0110011] GO:0005201; GO:0005509; GO:0005518; GO:0005576; GO:0005604; GO:0005886; GO:0007160; GO:0010811; GO:0032836; GO:0043236; GO:0043237; GO:0043394; GO:0045785; GO:0051149; GO:0062023; GO:0070062; GO:0071711; GO:0098637; GO:0110011; GO:2001046 32367 XM_029358234.2 323 258 126 275 806 P14543 5.29e-43 Nidogen-1 (NID-1) (Entactin) Homo sapiens (Human) basement membrane organization [GO:0071711]; cell-matrix adhesion [GO:0007160]; glomerular basement membrane development [GO:0032836]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of muscle cell differentiation [GO:0051149]; regulation of basement membrane organization [GO:0110011] GO:0005201; GO:0005509; GO:0005518; GO:0005576; GO:0005604; GO:0005886; GO:0007160; GO:0010811; GO:0032836; GO:0043236; GO:0043237; GO:0043394; GO:0045785; GO:0051149; GO:0062023; GO:0070062; GO:0071711; GO:0098637; GO:0110011; GO:2001046 32368 XM_029358234.2 323 258 126 275 806 P14543 5.58e-22 Nidogen-1 (NID-1) (Entactin) Homo sapiens (Human) basement membrane organization [GO:0071711]; cell-matrix adhesion [GO:0007160]; glomerular basement membrane development [GO:0032836]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of muscle cell differentiation [GO:0051149]; regulation of basement membrane organization [GO:0110011] GO:0005201; GO:0005509; GO:0005518; GO:0005576; GO:0005604; GO:0005886; GO:0007160; GO:0010811; GO:0032836; GO:0043236; GO:0043237; GO:0043394; GO:0045785; GO:0051149; GO:0062023; GO:0070062; GO:0071711; GO:0098637; GO:0110011; GO:2001046 32369 XM_029331793.2 1449 1034 1010 1599 2176 Q8BWU8 2.47e-173 Ethanolamine-phosphate phospho-lyase (EC 4.2.3.2) (Alanine--glyoxylate aminotransferase 2-like 1) Mus musculus (Mouse) NA GO:0005739; GO:0008483; GO:0030170; GO:0050459 32370 XR_003824273.2 226 362 56 1125 176 NA NA NA NA NA NA 32371 XM_044319099.1 5697 4221 2747 5300 4647 Q8BZZ3 0 NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase WWP1) (WW domain-containing protein 1) Mus musculus (Mouse) lung development [GO:0030324]; negative regulation of DNA-templated transcription [GO:0045892]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; T cell differentiation [GO:0030217] GO:0000209; GO:0004842; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0016567; GO:0030217; GO:0030324; GO:0043161; GO:0045892; GO:0061630 32372 XM_029335737.2 0 18 0 13 7 Q2KIP6 9.67e-23 Kappa-type opioid receptor (K-OR-1) (KOR-1) Bos taurus (Bovine) adenylate cyclase-inhibiting opioid receptor signaling pathway [GO:0031635]; defense response to virus [GO:0051607]; G protein-coupled opioid receptor signaling pathway [GO:0038003]; immune response [GO:0006955]; locomotory behavior [GO:0007626]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; regulation of saliva secretion [GO:0046877]; sensory perception of pain [GO:0019233] GO:0004930; GO:0004985; GO:0005654; GO:0005829; GO:0005886; GO:0006955; GO:0007200; GO:0007218; GO:0007626; GO:0016020; GO:0019233; GO:0031635; GO:0038003; GO:0038048; GO:0042277; GO:0042923; GO:0043005; GO:0046877; GO:0051607 32373 XR_006395179.1 52 24 13 8 20 A0JM24 2.78e-48 NADP-dependent oxidoreductase domain-containing protein 1 (EC 1.-.-.-) (Pyrroline-5-carboxylate reductase-like protein C14orf148 homolog) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0016491 32374 XR_006394040.1 16 0 1 11 0 NA NA NA NA NA NA 32375 XM_029336748.2 2422 1702 1274 1276 1549 Q6UWE0 1.55e-140 E3 ubiquitin-protein ligase LRSAM1 (EC 2.3.2.27) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (RING-type E3 ubiquitin transferase LRSAM1) (Tsg101-associated ligase) (hTAL) Homo sapiens (Human) autophagy [GO:0006914]; negative regulation of endocytosis [GO:0045806]; positive regulation of autophagosome assembly [GO:2000786]; positive regulation of xenophagy [GO:1904417]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein polyubiquitination [GO:0000209]; ubiquitin-dependent endocytosis [GO:0070086]; viral budding [GO:0046755] GO:0000209; GO:0004842; GO:0005737; GO:0005829; GO:0006914; GO:0016020; GO:0030163; GO:0045806; GO:0046755; GO:0046872; GO:0051865; GO:0061630; GO:0070086; GO:1904417; GO:2000786 32376 XM_029329025.2 1055 1672 1522 1626 1849 Q8NHR9 1.31e-28 Profilin-4 (Profilin IV) Homo sapiens (Human) acrosome assembly [GO:0001675]; flagellated sperm motility [GO:0030317]; manchette assembly [GO:1905198]; sequestering of actin monomers [GO:0042989]; sperm flagellum assembly [GO:0120316]; spermatogenesis [GO:0007283] GO:0001675; GO:0003785; GO:0005856; GO:0005938; GO:0007283; GO:0008289; GO:0030317; GO:0042989; GO:0120316; GO:1905198 32377 XM_029339361.2 4094 5378 3277 3829 2471 NA NA NA NA NA NA 32378 XM_044324785.1 858 62 135 209 505 NA NA NA NA NA NA 32379 XR_006393371.1 23 5 0 19 50 NA NA NA NA NA NA 32380 XM_044308146.1 4 0 19 2 0 NA NA NA NA NA NA 32381 XM_029355209.2 503 194 102 164 199 P52758 5.94e-51 2-iminobutanoate/2-iminopropanoate deaminase (EC 3.5.99.10) (14.5 kDa translational inhibitor protein) (hp14.5) (p14.5) (Heat-responsive protein 12) (Reactive intermediate imine deaminase A homolog) (Translation inhibitor L-PSP ribonuclease) (UK114 antigen homolog) Homo sapiens (Human) brain development [GO:0007420]; G1 to G0 transition [GO:0070314]; kidney development [GO:0001822]; L-threonine catabolic process to glycine [GO:0019518]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; mRNA catabolic process [GO:0006402]; mRNA destabilization [GO:0061157]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of translation [GO:0017148]; organonitrogen compound catabolic process [GO:1901565]; response to lipid [GO:0033993]; response to salt [GO:1902074] GO:0001822; GO:0003723; GO:0003729; GO:0005634; GO:0005737; GO:0005739; GO:0005759; GO:0005777; GO:0005829; GO:0006402; GO:0006629; GO:0007420; GO:0016892; GO:0017148; GO:0019239; GO:0019518; GO:0030324; GO:0033993; GO:0036041; GO:0042802; GO:0046914; GO:0050680; GO:0061157; GO:0070062; GO:0070314; GO:0120242; GO:0120243; GO:1901565; GO:1902074 32382 XM_029349799.2 18 2 1 5 22 NA NA NA NA NA NA 32383 XR_006397159.1 835 1271 723 609 1179 Q21029 8.83e-21 Mitogen-activated protein kinase kinase kinase nsy-1 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 1) (ASK-1) (Neuronal symmetry kinase 1) Caenorhabditis elegans cell fate commitment [GO:0045165]; chemotaxis [GO:0006935]; defense response to fungus [GO:0050832]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; determination of adult lifespan [GO:0008340]; determination of left/right asymmetry in nervous system [GO:0035545]; innate immune response [GO:0045087]; MAPK cascade [GO:0000165]; oviposition [GO:0018991]; p38MAPK cascade [GO:0038066]; positive regulation of gene expression [GO:0010628]; positive regulation of oviposition [GO:1901046]; positive regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium [GO:1902097]; protein phosphorylation [GO:0006468]; response to nematicide [GO:0093002]; response to oxidative stress [GO:0006979]; response to starvation [GO:0042594] GO:0000165; GO:0004672; GO:0004709; GO:0004712; GO:0005524; GO:0006468; GO:0006935; GO:0006979; GO:0008340; GO:0010628; GO:0014069; GO:0018991; GO:0031434; GO:0035545; GO:0038066; GO:0042594; GO:0043025; GO:0043204; GO:0045087; GO:0045165; GO:0046872; GO:0050829; GO:0050830; GO:0050832; GO:0093002; GO:0106310; GO:1901046; GO:1902097; GO:1904115 32384 XM_029349736.2 1894 1207 1004 1397 1270 Q1HFZ0 1.33e-146 RNA cytosine C(5)-methyltransferase NSUN2 (EC 2.1.1.-) (Myc-induced SUN domain-containing protein) (Misu) (NOL1/NOP2/Sun domain family member 2) (mRNA cytosine C(5)-methyltransferase) (EC 2.1.1.-) (tRNA cytosine C(5)-methyltransferase) (EC 2.1.1.-, EC 2.1.1.203) Mus musculus (Mouse) cell division [GO:0051301]; hair follicle maturation [GO:0048820]; in utero embryonic development [GO:0001701]; meiotic cell cycle checkpoint signaling [GO:0033313]; mRNA methylation [GO:0080009]; regulation of mRNA export from nucleus [GO:0010793]; regulation of stem cell differentiation [GO:2000736]; RNA methylation [GO:0001510]; spermatid development [GO:0007286]; tRNA methylation [GO:0030488]; tRNA stabilization [GO:0036416] GO:0000049; GO:0001510; GO:0001701; GO:0005634; GO:0005730; GO:0005737; GO:0005739; GO:0005819; GO:0007286; GO:0008168; GO:0010793; GO:0016428; GO:0030488; GO:0033313; GO:0033391; GO:0036416; GO:0048820; GO:0051301; GO:0062152; GO:0070062; GO:0080009; GO:2000736 32385 XM_029349736.2 1894 1207 1004 1397 1270 Q1HFZ0 2.24e-43 RNA cytosine C(5)-methyltransferase NSUN2 (EC 2.1.1.-) (Myc-induced SUN domain-containing protein) (Misu) (NOL1/NOP2/Sun domain family member 2) (mRNA cytosine C(5)-methyltransferase) (EC 2.1.1.-) (tRNA cytosine C(5)-methyltransferase) (EC 2.1.1.-, EC 2.1.1.203) Mus musculus (Mouse) cell division [GO:0051301]; hair follicle maturation [GO:0048820]; in utero embryonic development [GO:0001701]; meiotic cell cycle checkpoint signaling [GO:0033313]; mRNA methylation [GO:0080009]; regulation of mRNA export from nucleus [GO:0010793]; regulation of stem cell differentiation [GO:2000736]; RNA methylation [GO:0001510]; spermatid development [GO:0007286]; tRNA methylation [GO:0030488]; tRNA stabilization [GO:0036416] GO:0000049; GO:0001510; GO:0001701; GO:0005634; GO:0005730; GO:0005737; GO:0005739; GO:0005819; GO:0007286; GO:0008168; GO:0010793; GO:0016428; GO:0030488; GO:0033313; GO:0033391; GO:0036416; GO:0048820; GO:0051301; GO:0062152; GO:0070062; GO:0080009; GO:2000736 32386 XR_006393452.1 40 4 4 40 0 NA NA NA NA NA NA 32387 XM_029356348.2 21026 18923 13640 19557 16920 P30676 0 Guanine nucleotide-binding protein G(i) subunit alpha (Adenylate cyclase-inhibiting G alpha protein) Patiria pectinifera (Starfish) (Asterina pectinifera) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188] GO:0003924; GO:0005525; GO:0007188; GO:0031683; GO:0046872; GO:0110165 32388 XM_029336243.2 615 310 396 527 537 Q14432 3.36e-131 cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A) (cGMP-inhibited cAMP phosphodiesterase) (cGI-PDE) Homo sapiens (Human) apoptotic signaling pathway [GO:0097190]; cAMP-mediated signaling [GO:0019933]; cellular response to cGMP [GO:0071321]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP-mediated signaling [GO:0019934]; G protein-coupled receptor signaling pathway [GO:0007186]; lipid metabolic process [GO:0006629]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of vascular permeability [GO:0043116]; oocyte maturation [GO:0001556]; positive regulation of oocyte development [GO:0060282]; positive regulation of vascular permeability [GO:0043117]; regulation of meiotic nuclear division [GO:0040020]; regulation of ribonuclease activity [GO:0060700]; response to xenobiotic stimulus [GO:0009410]; signal transduction [GO:0007165] GO:0001556; GO:0004114; GO:0004115; GO:0004119; GO:0005829; GO:0006629; GO:0007165; GO:0007186; GO:0009410; GO:0016020; GO:0019933; GO:0019934; GO:0040020; GO:0043066; GO:0043116; GO:0043117; GO:0043951; GO:0046872; GO:0047555; GO:0060282; GO:0060700; GO:0071321; GO:0071560; GO:0097190; GO:0099130 32389 XM_029326988.2 656 552 523 662 744 NA NA NA NA NA NA 32390 XM_044318060.1 2459 2724 1504 2533 1772 P80317 0 T-complex protein 1 subunit zeta (TCP-1-zeta) (CCT-zeta-1) Mus musculus (Mouse) binding of sperm to zona pellucida [GO:0007339]; chaperone-mediated protein folding [GO:0061077]; positive regulation of establishment of protein localization to telomere [GO:1904851]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein folding [GO:0006457]; protein stabilization [GO:0050821]; toxin transport [GO:1901998] GO:0001669; GO:0002199; GO:0005524; GO:0005829; GO:0005832; GO:0005874; GO:0006457; GO:0007339; GO:0016887; GO:0032212; GO:0044183; GO:0044297; GO:0050821; GO:0051082; GO:0061077; GO:0071987; GO:0140662; GO:1901998; GO:1904851 32391 XM_029333885.2 1159 621 821 1488 1537 NA NA NA NA NA NA 32392 XR_003828610.1 1 0 5 0 6 NA NA NA NA NA NA 32393 XM_044323225.1 48 0 0 1 6 NA NA NA NA NA NA 32394 XR_006396747.1 310 124 163 370 166 NA NA NA NA NA NA 32395 XR_006391920.1 12 105 51 8 93 NA NA NA NA NA NA 32396 XM_029348079.2 1624 387 722 482 1334 Q8K268 0 ATP-binding cassette sub-family F member 3 Mus musculus (Mouse) defense response to virus [GO:0051607] GO:0005524; GO:0016887; GO:0051607 32397 XM_029338884.2 141 239 100 210 226 NA NA NA NA NA NA 32398 XM_044319479.1 879 1538 570 1411 25 NA NA NA NA NA NA 32399 XM_029333324.2 669 340 342 173 260 NA NA NA NA NA NA 32400 XM_044317038.1 171 223 183 120 104 P01123 1.79e-47 GTP-binding protein YPT1 (Protein YP2) (Rab GTPase YPT1) (Transport GTPase YPT1) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) autophagosome assembly [GO:0000045]; COPII-coated vesicle budding [GO:0090114]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; early endosome to Golgi transport [GO:0034498]; endocytic recycling [GO:0032456]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi vesicle budding [GO:0048194]; Golgi vesicle docking [GO:0048211]; intracellular protein transport [GO:0006886]; macroautophagy [GO:0016236]; pre-mRNA catabolic process [GO:1990261]; protein localization to phagophore assembly site [GO:0034497]; regulation of endoplasmic reticulum unfolded protein response [GO:1900101]; regulation of kinase activity [GO:0043549]; reticulophagy [GO:0061709]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; SNARE complex assembly [GO:0035493]; SNARE complex disassembly [GO:0035494] GO:0000045; GO:0000139; GO:0000149; GO:0000407; GO:0003924; GO:0005525; GO:0005739; GO:0005789; GO:0005795; GO:0005801; GO:0005829; GO:0006886; GO:0006888; GO:0006890; GO:0012505; GO:0016236; GO:0031410; GO:0032258; GO:0032456; GO:0034045; GO:0034497; GO:0034498; GO:0035493; GO:0035494; GO:0043549; GO:0048194; GO:0048211; GO:0061709; GO:0090114; GO:1900101; GO:1990261 32401 XM_044314520.1 139 100 153 164 152 NA NA NA NA NA NA 32402 XM_044321324.1 103 61 99 72 75 NA NA NA NA NA NA 32403 XM_029343920.2 365 211 154 383 356 Q008S8 0 Epithelial cell-transforming sequence 2 oncogene-like (Lung-specific F-box and DH domain-containing protein) (Putative guanine nucleotide exchange factor LFDH) Homo sapiens (Human) NA GO:0005085 32404 XR_003824329.1 3 1 6 12 2 NA NA NA NA NA NA 32405 XM_029351402.2 0 42 89 36 97 P34410 7.03e-26 TWiK family of potassium channels protein 7 Caenorhabditis elegans potassium ion transmembrane transport [GO:0071805]; stabilization of membrane potential [GO:0030322] GO:0005886; GO:0015271; GO:0022841; GO:0030322; GO:0071805 32406 XM_044311786.1 86 149 19 128 218 NA NA NA NA NA NA 32407 XM_044327642.1 37 79 11 32 28 Q8BVT6 3.61e-35 Protein phosphatase 2C-like domain-containing protein 1 Mus musculus (Mouse) protein dephosphorylation [GO:0006470] GO:0004722; GO:0006470 32408 XM_029329037.2 71 11 0 55 0 Q8CGF5 1.28e-54 TLC domain-containing protein 4 (Transmembrane protein 56) Mus musculus (Mouse) lipid homeostasis [GO:0055088] GO:0005783; GO:0016020; GO:0055088 32409 XM_044316140.1 0 0 7 18 1 NA NA NA NA NA NA 32410 XM_044320987.1 5 4 6 8 48 NA NA NA NA NA NA 32411 XM_044317274.1 0 2 0 28 0 NA NA NA NA NA NA 32412 XR_006395653.1 0 0 0 17 0 NA NA NA NA NA NA 32413 XR_003825384.2 221 19 24 69 4 NA NA NA NA NA NA 32414 XM_044321624.1 22 0 20 5 9 Q9D110 2.17e-57 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) (5,10-methenyl-tetrahydrofolate synthetase) (MTHFS) (Methenyl-THF synthetase) Mus musculus (Mouse) DNA geometric change [GO:0032392]; DNA-templated transcription termination [GO:0006353]; folic acid catabolic process [GO:0046657]; folic acid-containing compound biosynthetic process [GO:0009396]; glutamate metabolic process [GO:0006536]; termination of mitochondrial transcription [GO:0006393]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653] GO:0003690; GO:0005524; GO:0005542; GO:0005737; GO:0005739; GO:0005759; GO:0005829; GO:0006353; GO:0006393; GO:0006536; GO:0009396; GO:0030272; GO:0032392; GO:0035999; GO:0042645; GO:0046653; GO:0046657; GO:0046872 32415 XM_044316607.1 29 0 1 63 2 NA NA NA NA NA NA 32416 XM_044315382.1 5 0 0 22 43 P04323 2.1e-66 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 32417 XM_029323798.2 239 0 104 18 19 A0FKN5 4.19e-131 NA NA NA NA 32418 XM_029356681.2 1300 992 874 1267 1254 P56517 0 Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-) Gallus gallus (Chicken) chromatin organization [GO:0006325]; circadian regulation of gene expression [GO:0032922]; DNA methylation-dependent heterochromatin formation [GO:0006346]; embryonic digit morphogenesis [GO:0042733]; endoderm development [GO:0007492]; epidermal cell differentiation [GO:0009913]; eyelid development in camera-type eye [GO:0061029]; fungiform papilla formation [GO:0061198]; hippocampus development [GO:0021766]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endopeptidase activity [GO:0052548]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000118; GO:0000122; GO:0000792; GO:0000979; GO:0001222; GO:0002039; GO:0003714; GO:0004407; GO:0005634; GO:0005737; GO:0005829; GO:0006325; GO:0006346; GO:0006357; GO:0007492; GO:0008284; GO:0009913; GO:0016580; GO:0016581; GO:0017053; GO:0021766; GO:0030182; GO:0032922; GO:0035851; GO:0042733; GO:0042826; GO:0043025; GO:0043124; GO:0043922; GO:0045944; GO:0047485; GO:0048709; GO:0048714; GO:0051059; GO:0052548; GO:0060766; GO:0061029; GO:0061198; GO:0070888; GO:0070932; GO:0070933; GO:0090090; GO:0140297; GO:0160009; GO:1990841; GO:2000273; GO:2001243 32419 XR_006397427.1 15 4 7 31 75 NA NA NA NA NA NA 32420 XM_029345039.2 203 62 0 198 0 NA NA NA NA NA NA 32421 XM_044325543.1 56 57 64 37 88 NA NA NA NA NA NA 32422 XR_006397181.1 11 0 4 5 39 P43141 1.55e-26 Beta-4C adrenergic receptor (Beta-4C adrenoreceptor) (Beta-4C adrenoceptor) Meleagris gallopavo (Wild turkey) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; positive regulation of heart contraction [GO:0045823] GO:0004940; GO:0005886; GO:0007189; GO:0045823 32423 XM_029333764.2 1708 977 732 1244 1459 Q28FH2 0 N-terminal kinase-like protein (SCY1-like protein 1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) protein phosphorylation [GO:0006468] GO:0004672; GO:0005524; GO:0006468 32424 XM_029334135.2 985 1035 773 768 821 Q96P53 8.88e-163 WD repeat and FYVE domain-containing protein 2 (Propeller-FYVE protein) (Prof) (WD40- and FYVE domain-containing protein 2) (Zinc finger FYVE domain-containing protein 22) Homo sapiens (Human) positive regulation of fat cell differentiation [GO:0045600]; positive regulation of protein phosphorylation [GO:0001934] GO:0001934; GO:0005769; GO:0031982; GO:0043231; GO:0045600; GO:0046872 32425 XM_029358049.2 84 353 38 427 132 Q5R4G6 0 Cullin-1 (CUL-1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; cell population proliferation [GO:0008283]; protein K48-linked ubiquitination [GO:0070936]; protein monoubiquitination [GO:0006513]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0005886; GO:0006513; GO:0006915; GO:0008283; GO:0009887; GO:0019005; GO:0031146; GO:0031625; GO:0070936; GO:1990452 32426 XM_044327257.1 634 180 840 371 1158 Q3UZV7 1.58e-27 Endosome/lysosome-associated apoptosis and autophagy regulator family member 2 (Estrogen-induced gene 121-like protein) Mus musculus (Mouse) negative regulation of nervous system development [GO:0051961]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of epidermis development [GO:0045684] GO:0005886; GO:0016020; GO:0030513; GO:0045684; GO:0051961; GO:0070700 32427 XM_029348065.2 8 3 0 2 5 P97295 6.53e-26 Neuropeptide Y receptor type 2 (NPY2-R) (NPY-Y2 receptor) (Y2 receptor) Mus musculus (Mouse) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; behavioral fear response [GO:0001662]; cardiac left ventricle morphogenesis [GO:0003214]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of feeding behavior [GO:2000252]; negative regulation of nervous system process [GO:0031645]; negative regulation of secretion [GO:0051048]; negative regulation of synaptic transmission [GO:0050805]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nitric oxide mediated signal transduction [GO:0007263]; outflow tract morphogenesis [GO:0003151]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of circadian sleep/wake cycle, non-REM sleep [GO:0046010]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of dopamine secretion [GO:0033603]; positive regulation of peptide secretion [GO:0002793]; positive regulation of smooth muscle contraction [GO:0045987]; regulation of sensory perception of pain [GO:0051930]; secretion [GO:0046903] GO:0001601; GO:0001662; GO:0002793; GO:0003151; GO:0003214; GO:0004983; GO:0005886; GO:0005929; GO:0007186; GO:0007193; GO:0007204; GO:0007263; GO:0008188; GO:0010811; GO:0016020; GO:0031645; GO:0033603; GO:0042923; GO:0043005; GO:0043951; GO:0045987; GO:0046010; GO:0046903; GO:0050805; GO:0051048; GO:0051930; GO:0051967; GO:0090394; GO:0097730; GO:2000252 32428 XM_044307330.1 97 24 27 81 136 NA NA NA NA NA NA 32429 XM_029358516.2 1 16 2 0 6 NA NA NA NA NA NA 32430 XM_029346455.2 15 9 22 65 15 NA NA NA NA NA NA 32431 XM_029349717.2 55 79 6 38 37 NA NA NA NA NA NA 32432 XM_044311604.1 0 18 0 0 48 P54132 3.22e-35 RecQ-like DNA helicase BLM (EC 3.6.4.12) (Bloom syndrome protein) (DNA helicase, RecQ-like type 2) (RecQ2) (RecQ protein-like 3) Homo sapiens (Human) cellular response to camptothecin [GO:0072757]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hydroxyurea [GO:0072711]; cellular response to ionizing radiation [GO:0071479]; DNA double-strand break processing [GO:0000729]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724]; G-quadruplex DNA unwinding [GO:0044806]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; negative regulation of cell division [GO:0051782]; negative regulation of DNA recombination [GO:0045910]; positive regulation of DNA-templated transcription [GO:0045893]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of DNA-templated DNA replication [GO:0090329]; replication fork processing [GO:0031297]; replication fork protection [GO:0048478]; resolution of recombination intermediates [GO:0071139]; response to X-ray [GO:0010165]; t-circle formation [GO:0090656]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; telomeric D-loop disassembly [GO:0061820] GO:0000079; GO:0000228; GO:0000400; GO:0000403; GO:0000405; GO:0000723; GO:0000724; GO:0000729; GO:0000800; GO:0002039; GO:0003677; GO:0003678; GO:0003697; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0005657; GO:0005694; GO:0005730; GO:0005737; GO:0005829; GO:0006260; GO:0006268; GO:0006281; GO:0006310; GO:0006974; GO:0007095; GO:0008094; GO:0008270; GO:0009378; GO:0010165; GO:0016363; GO:0016605; GO:0016887; GO:0031297; GO:0031422; GO:0032201; GO:0032508; GO:0032991; GO:0042802; GO:0042803; GO:0043138; GO:0044806; GO:0045893; GO:0045910; GO:0048478; GO:0051259; GO:0051260; GO:0051782; GO:0051880; GO:0061749; GO:0061820; GO:0061821; GO:0061849; GO:0071139; GO:0071479; GO:0072711; GO:0072757; GO:0090329; GO:0090656; GO:0140677; GO:1905773; GO:1990814 32433 XM_029351988.2 558 366 253 383 312 NA NA NA NA NA NA 32434 XM_044322365.1 3 0 9 6 29 NA NA NA NA NA NA 32435 XM_044317386.1 81 0 0 0 0 NA NA NA NA NA NA 32436 XR_003823015.1 29 34 56 30 35 NA NA NA NA NA NA 32437 XR_006391909.1 63 90 40 210 102 NA NA NA NA NA NA 32438 XM_044315510.1 87 46 52 63 79 Q96AY4 1.7e-146 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32439 XM_044315510.1 87 46 52 63 79 Q96AY4 5.5e-106 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32440 XM_044315510.1 87 46 52 63 79 Q96AY4 1.23e-104 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32441 XM_044315510.1 87 46 52 63 79 Q96AY4 3.72e-101 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32442 XM_029354671.2 1032 454 248 757 1406 O15992 0 Arginine kinase (AK) (EC 2.7.3.3) Anthopleura japonica (Sea anemone) phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310] GO:0004054; GO:0004111; GO:0005524; GO:0016310; GO:0046314 32443 XM_044316147.1 0 0 11 1 4 NA NA NA NA NA NA 32444 XM_044328076.1 2169 1550 1092 1551 974 NA NA NA NA NA NA 32445 XM_044314120.1 1 7 9 9 21 Q94K49 1.02e-32 Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1 (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) epigenetic regulation of gene expression [GO:0040029] GO:0003682; GO:0004518; GO:0005634; GO:0035098; GO:0035102; GO:0040029; GO:0046872 32446 XR_006397009.1 18 84 10 24 18 NA NA NA NA NA NA 32447 XM_044307425.1 14 3 4 14 11 B8V7S0 5.44e-46 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 32448 XM_029357050.2 7298 6164 4621 6821 7638 P25867 2.15e-98 Ubiquitin-conjugating enzyme E2-17 kDa (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme D1) (Protein effete) (Ubiquitin carrier protein) (Ubiquitin-protein ligase) Drosophila melanogaster (Fruit fly) anaphase-promoting complex-dependent catabolic process [GO:0031145]; chromosome organization [GO:0051276]; compound eye morphogenesis [GO:0001745]; compound eye photoreceptor cell differentiation [GO:0001751]; female germ-line stem cell asymmetric division [GO:0048132]; germ-line stem cell population maintenance [GO:0030718]; male meiotic nuclear division [GO:0007140]; mitotic cell cycle [GO:0000278]; negative regulation of smoothened signaling pathway [GO:0045879]; neuron remodeling [GO:0016322]; peptidoglycan recognition protein signaling pathway [GO:0061057]; protein linear polyubiquitination [GO:0097039]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of protein stability [GO:0031647]; regulation of R7 cell differentiation [GO:0045676]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000209; GO:0000278; GO:0001745; GO:0001751; GO:0005524; GO:0005634; GO:0005829; GO:0006511; GO:0007140; GO:0016322; GO:0016567; GO:0030718; GO:0031145; GO:0031625; GO:0031647; GO:0045676; GO:0045879; GO:0048132; GO:0051276; GO:0061057; GO:0061631; GO:0097039 32449 XM_029355671.2 57 34 19 90 84 NA NA NA NA NA NA 32450 XR_006396766.1 9 0 9 6 15 NA NA NA NA NA NA 32451 XM_044312740.1 0 34 0 91 130 Q923S8 0 4'-phosphopantetheine phosphatase (EC 3.1.3.-) (Inactive pantothenic acid kinase 4) (rPanK4) Rattus norvegicus (Rat) coenzyme A biosynthetic process [GO:0015937] GO:0004594; GO:0005524; GO:0005634; GO:0005829; GO:0015937; GO:0016787; GO:0046872 32452 XR_006396922.1 39 17 37 56 142 NA NA NA NA NA NA 32453 XM_044321788.1 213 94 49 43 52 NA NA NA NA NA NA 32454 XM_029349469.2 3368 2780 1974 3157 2220 P82808 0 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (EC 2.6.1.16) (D-fructose-6-phosphate amidotransferase 1) (Glutamine:fructose-6-phosphate amidotransferase 1) (GFAT 1) (GFAT1) (Hexosephosphate aminotransferase 1) Rattus norvegicus (Rat) cellular response to insulin stimulus [GO:0032869]; circadian regulation of gene expression [GO:0032922]; fructose 6-phosphate metabolic process [GO:0006002]; glucosamine biosynthetic process [GO:0006042]; glutamine metabolic process [GO:0006541]; negative regulation of glycogen biosynthetic process [GO:0045719]; protein N-linked glycosylation [GO:0006487]; response to insulin [GO:0032868]; response to sucrose [GO:0009744]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047] GO:0004360; GO:0006002; GO:0006042; GO:0006047; GO:0006048; GO:0006487; GO:0006541; GO:0009744; GO:0016597; GO:0030246; GO:0032868; GO:0032869; GO:0032922; GO:0042802; GO:0045719; GO:0097367 32455 XM_029327693.2 422 169 591 0 776 Q96DM1 7.5e-53 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 32456 XM_044327741.1 33 13 8 37 117 NA NA NA NA NA NA 32457 XM_029357008.2 2107 1069 1028 1436 1464 Q5ZHS0 4.71e-27 BRCA1-A complex subunit Abraxas 1 (Coiled-coil domain-containing protein 98) (Protein FAM175A) Gallus gallus (Chicken) attachment of spindle microtubules to kinetochore [GO:0008608]; chromatin organization [GO:0006325]; double-strand break repair [GO:0006302]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; mitotic spindle assembly [GO:0090307]; positive regulation of DNA repair [GO:0045739]; protein K63-linked deubiquitination [GO:0070536]; response to ionizing radiation [GO:0010212] GO:0005634; GO:0006302; GO:0006325; GO:0007095; GO:0008017; GO:0008608; GO:0010212; GO:0031593; GO:0045739; GO:0070531; GO:0070536; GO:0090307 32458 XM_044318281.1 0 5 4 0 12 NA NA NA NA NA NA 32459 XM_044318897.1 464 236 177 313 263 O43426 0 Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1) Homo sapiens (Human) brain development [GO:0007420]; inositol phosphate dephosphorylation [GO:0046855]; inositol phosphate metabolic process [GO:0043647]; learning [GO:0007612]; membrane organization [GO:0061024]; neurotransmitter transport [GO:0006836]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; phosphatidylinositol metabolic process [GO:0046488]; positive regulation of endosome organization [GO:1904980]; positive regulation of gliogenesis [GO:0014015]; positive regulation of receptor-mediated endocytosis [GO:0048260]; response to cytokine [GO:0034097]; response to retinoic acid [GO:0032526]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle priming [GO:0016082]; synaptic vesicle transport [GO:0048489]; synaptic vesicle uncoating [GO:0016191] GO:0003723; GO:0004438; GO:0004439; GO:0005829; GO:0005874; GO:0006661; GO:0006836; GO:0007420; GO:0007612; GO:0008022; GO:0012506; GO:0014015; GO:0016082; GO:0016191; GO:0017124; GO:0030117; GO:0030132; GO:0032526; GO:0034097; GO:0034595; GO:0034596; GO:0043195; GO:0043647; GO:0043812; GO:0043813; GO:0044877; GO:0046488; GO:0046855; GO:0046856; GO:0048260; GO:0048471; GO:0048488; GO:0048489; GO:0052629; GO:0052658; GO:0061024; GO:0097060; GO:0098688; GO:0098793; GO:1904980; GO:1990175 32460 XM_044318897.1 464 236 177 313 263 O43426 9.96e-21 Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1) Homo sapiens (Human) brain development [GO:0007420]; inositol phosphate dephosphorylation [GO:0046855]; inositol phosphate metabolic process [GO:0043647]; learning [GO:0007612]; membrane organization [GO:0061024]; neurotransmitter transport [GO:0006836]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; phosphatidylinositol metabolic process [GO:0046488]; positive regulation of endosome organization [GO:1904980]; positive regulation of gliogenesis [GO:0014015]; positive regulation of receptor-mediated endocytosis [GO:0048260]; response to cytokine [GO:0034097]; response to retinoic acid [GO:0032526]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle priming [GO:0016082]; synaptic vesicle transport [GO:0048489]; synaptic vesicle uncoating [GO:0016191] GO:0003723; GO:0004438; GO:0004439; GO:0005829; GO:0005874; GO:0006661; GO:0006836; GO:0007420; GO:0007612; GO:0008022; GO:0012506; GO:0014015; GO:0016082; GO:0016191; GO:0017124; GO:0030117; GO:0030132; GO:0032526; GO:0034097; GO:0034595; GO:0034596; GO:0043195; GO:0043647; GO:0043812; GO:0043813; GO:0044877; GO:0046488; GO:0046855; GO:0046856; GO:0048260; GO:0048471; GO:0048488; GO:0048489; GO:0052629; GO:0052658; GO:0061024; GO:0097060; GO:0098688; GO:0098793; GO:1904980; GO:1990175 32461 XM_029336857.2 1532 1942 1202 2886 1159 NA NA NA NA NA NA 32462 XM_044311336.1 305 776 816 691 7 B0S5N4 0 Plexin A3 Danio rerio (Zebrafish) (Brachydanio rerio) axon extension [GO:0048675]; branching morphogenesis of a nerve [GO:0048755]; embryonic skeletal joint morphogenesis [GO:0060272]; motor neuron axon guidance [GO:0008045]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of collateral sprouting in absence of injury [GO:0048696]; regulation of GTPase activity [GO:0043087]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287] GO:0002116; GO:0005886; GO:0007162; GO:0008045; GO:0008360; GO:0016020; GO:0017154; GO:0030334; GO:0042802; GO:0043087; GO:0048675; GO:0048696; GO:0048755; GO:0050772; GO:0060272; GO:1902287 32463 XM_044307353.1 26 57 9 5 17 P0DP43 1.92e-27 Cation channel sperm-associated auxiliary subunit epsilon (CatSper-epsilon) (CatSperepsilon) (C1orf101-like protein) Mus musculus (Mouse) flagellated sperm motility [GO:0030317]; sperm capacitation [GO:0048240] GO:0030317; GO:0036128; GO:0048240; GO:0097228 32464 XM_029337580.2 215 76 520 283 776 B6ZLK2 0 Chromodomain-helicase-DNA-binding protein 1 (CHD-1) (EC 3.6.4.12) (ATP-dependent helicase CHD1) Gallus gallus (Chicken) chromatin remodeling [GO:0006338]; nucleosome organization [GO:0034728]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000775; GO:0000785; GO:0003677; GO:0003682; GO:0004386; GO:0005524; GO:0005634; GO:0006338; GO:0006357; GO:0016887; GO:0034728; GO:0042393; GO:0140658 32465 XM_029337580.2 215 76 520 283 776 B6ZLK2 1.59e-27 Chromodomain-helicase-DNA-binding protein 1 (CHD-1) (EC 3.6.4.12) (ATP-dependent helicase CHD1) Gallus gallus (Chicken) chromatin remodeling [GO:0006338]; nucleosome organization [GO:0034728]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000775; GO:0000785; GO:0003677; GO:0003682; GO:0004386; GO:0005524; GO:0005634; GO:0006338; GO:0006357; GO:0016887; GO:0034728; GO:0042393; GO:0140658 32466 XM_029328430.2 35 6 41 10 84 NA NA NA NA NA NA 32467 XM_044316714.1 175 40 0 354 1121 P02752 1.21e-36 Riboflavin-binding protein (RBP) [Cleaved into: Riboflavin-binding protein, plasma form; Riboflavin-binding protein, yolk major form; Riboflavin-binding protein, yolk minor form] Gallus gallus (Chicken) negative regulation of sensory perception of bitter taste [GO:1904661]; negative regulation of sensory perception of sweet taste [GO:1904657]; riboflavin transport [GO:0032218] GO:0009897; GO:0032217; GO:0032218; GO:0038023; GO:1902444; GO:1904657; GO:1904661 32468 XM_044324717.1 10 0 0 3 1 NA NA NA NA NA NA 32469 XM_044311139.1 16 4 0 0 102 Q8BUZ3 1.22e-29 Tigger transposable element-derived protein 4 Mus musculus (Mouse) NA GO:0003677; GO:0005634 32470 XM_044325706.1 0 0 0 100 0 Q12789 7.39e-72 General transcription factor 3C polypeptide 1 (TF3C-alpha) (TFIIIC box B-binding subunit) (Transcription factor IIIC 220 kDa subunit) (TFIIIC 220 kDa subunit) (TFIIIC220) (Transcription factor IIIC subunit alpha) Homo sapiens (Human) 5S class rRNA transcription by RNA polymerase III [GO:0042791]; rRNA transcription [GO:0009303]; transcription by RNA polymerase III [GO:0006383]; transcription initiation at RNA polymerase III promoter [GO:0006384]; tRNA transcription [GO:0009304]; tRNA transcription by RNA polymerase III [GO:0042797] GO:0000127; GO:0000995; GO:0003677; GO:0005654; GO:0005730; GO:0006383; GO:0006384; GO:0009303; GO:0009304; GO:0016020; GO:0042791; GO:0042797; GO:1990904 32471 XM_044325706.1 0 0 0 100 0 Q12789 5.75e-45 General transcription factor 3C polypeptide 1 (TF3C-alpha) (TFIIIC box B-binding subunit) (Transcription factor IIIC 220 kDa subunit) (TFIIIC 220 kDa subunit) (TFIIIC220) (Transcription factor IIIC subunit alpha) Homo sapiens (Human) 5S class rRNA transcription by RNA polymerase III [GO:0042791]; rRNA transcription [GO:0009303]; transcription by RNA polymerase III [GO:0006383]; transcription initiation at RNA polymerase III promoter [GO:0006384]; tRNA transcription [GO:0009304]; tRNA transcription by RNA polymerase III [GO:0042797] GO:0000127; GO:0000995; GO:0003677; GO:0005654; GO:0005730; GO:0006383; GO:0006384; GO:0009303; GO:0009304; GO:0016020; GO:0042791; GO:0042797; GO:1990904 32472 XM_029344175.2 1200 812 629 1035 711 NA NA NA NA NA NA 32473 XM_044316538.1 0 19 0 13 39 Q8BP78 5.58e-71 Protein FRA10AC1 homolog Mus musculus (Mouse) dephosphorylation [GO:0016311] GO:0005634; GO:0016311; GO:0016791 32474 XM_044317109.1 179 44 29 164 122 NA NA NA NA NA NA 32475 XM_029327607.2 3 8 0 0 4 Q0VAA2 4.82e-53 Leucine-rich repeat-containing protein 74A (Leucine-rich repeat-containing protein 74) Homo sapiens (Human) NA NA 32476 XM_044320175.1 0 0 579 1 866 NA NA NA NA NA NA 32477 XM_044324695.1 28 0 0 0 0 A1KZ92 4.43e-32 Probable oxidoreductase PXDNL (EC 1.-.-.-) (Cardiac peroxidase) (Inactive peroxidasin-like protein) (Polysomal ribonuclease 1) (PRM1) (Vascular peroxidase 2) Homo sapiens (Human) hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979] GO:0004519; GO:0004601; GO:0005615; GO:0005783; GO:0005886; GO:0006979; GO:0020037; GO:0042744; GO:0046872; GO:0140825 32478 XM_044324695.1 28 0 0 0 0 A1KZ92 3.79e-23 Probable oxidoreductase PXDNL (EC 1.-.-.-) (Cardiac peroxidase) (Inactive peroxidasin-like protein) (Polysomal ribonuclease 1) (PRM1) (Vascular peroxidase 2) Homo sapiens (Human) hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979] GO:0004519; GO:0004601; GO:0005615; GO:0005783; GO:0005886; GO:0006979; GO:0020037; GO:0042744; GO:0046872; GO:0140825 32479 XM_029330999.2 0 0 27 0 51 Q29R99 1.74e-79 Putative lipoyltransferase 2, mitochondrial (EC 2.3.1.181) (Lipoate-protein ligase B) (Lipoyl/octanoyl transferase) (Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase) Danio rerio (Zebrafish) (Brachydanio rerio) positive regulation of oxygen metabolic process [GO:2000376]; protein lipoylation [GO:0009249] GO:0005739; GO:0009249; GO:0016874; GO:0033819; GO:2000376 32480 XM_029336482.2 910 459 505 995 1111 Q14005 1.21e-34 Pro-interleukin-16 [Cleaved into: Interleukin-16 (IL-16) (Lymphocyte chemoattractant factor) (LCF)] Homo sapiens (Human) cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; induction of positive chemotaxis [GO:0050930]; leukocyte chemotaxis [GO:0030595]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 alpha production [GO:0032730]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of neutrophil activation [GO:1902565]; regulation of calcium ion transport [GO:0051924] GO:0005125; GO:0005576; GO:0005615; GO:0005829; GO:0005886; GO:0005925; GO:0006955; GO:0016607; GO:0019221; GO:0030595; GO:0032730; GO:0032735; GO:0032755; GO:0042609; GO:0050729; GO:0050930; GO:0051924; GO:0090543; GO:1902565 32481 XM_044318675.1 531 0 0 160 97 Q8IVV2 0 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 32482 XM_044318675.1 531 0 0 160 97 Q8IVV2 1.45e-169 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 32483 XM_044318675.1 531 0 0 160 97 Q8IVV2 2.23e-163 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 32484 XM_044318675.1 531 0 0 160 97 Q8IVV2 4.02e-154 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 32485 XM_044318675.1 531 0 0 160 97 Q8IVV2 2.26e-117 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 32486 XM_044318675.1 531 0 0 160 97 Q8IVV2 1.23e-107 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 32487 XM_029338200.2 61 66 10 100 58 O15973 1.27e-26 Rhodopsin, GQ-coupled (GQ-rhodopsin) Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis) phototransduction [GO:0007602]; visual perception [GO:0007601] GO:0004930; GO:0005886; GO:0007601; GO:0007602; GO:0009881 32488 XM_044311312.1 88 21 65 76 69 NA NA NA NA NA NA 32489 XM_029326842.2 175 88 43 47 63 NA NA NA NA NA NA 32490 XM_044319194.1 65 99 113 177 207 Q8K4Z4 5.63e-31 Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor) Cavia porcellus (Guinea pig) activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; bone resorption [GO:0045453]; brown fat cell differentiation [GO:0050873]; cellular response to amyloid-beta [GO:1904646]; desensitization of G protein-coupled receptor signaling pathway by arrestin [GO:0002032]; diet induced thermogenesis [GO:0002024]; heat generation [GO:0031649]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of smooth muscle contraction [GO:0045986]; norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0002025]; positive regulation of AMPA receptor activity [GO:2000969]; positive regulation of autophagosome maturation [GO:1901098]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of lipophagy [GO:1904504]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mini excitatory postsynaptic potential [GO:0061885]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor-mediated endocytosis [GO:0006898]; regulation of sodium ion transport [GO:0002028]; response to cold [GO:0009409]; smooth muscle contraction [GO:0006939]; transcription by RNA polymerase II [GO:0006366] GO:0001540; GO:0002024; GO:0002025; GO:0002028; GO:0002032; GO:0004941; GO:0005634; GO:0005769; GO:0005794; GO:0006366; GO:0006898; GO:0006939; GO:0007189; GO:0007190; GO:0008179; GO:0009409; GO:0010739; GO:0015459; GO:0016324; GO:0030501; GO:0031649; GO:0040015; GO:0042803; GO:0043235; GO:0043410; GO:0044877; GO:0045453; GO:0045944; GO:0045986; GO:0050873; GO:0051380; GO:0061885; GO:0071902; GO:0098992; GO:0120162; GO:1901098; GO:1904504; GO:1904646; GO:2000969 32491 XM_044308538.1 26 62 23 12 129 NA NA NA NA NA NA 32492 XM_044316878.1 353 288 284 270 505 Q9Z0U4 1.38e-116 Gamma-aminobutyric acid type B receptor subunit 1 (GABA-B receptor 1) (GABA-B-R1) (GABA-BR1) (GABABR1) (Gb1) Rattus norvegicus (Rat) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; chemical synaptic transmission [GO:0007268]; chemical synaptic transmission, postsynaptic [GO:0099565]; G protein-coupled receptor signaling pathway [GO:0007186]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of dopamine secretion [GO:0033602]; negative regulation of epinephrine secretion [GO:0032811]; negative regulation of gamma-aminobutyric acid secretion [GO:0014053]; negative regulation of synaptic transmission [GO:0050805]; neuron-glial cell signaling [GO:0150099]; osteoblast differentiation [GO:0001649]; positive regulation of glutamate secretion [GO:0014049]; positive regulation of growth hormone secretion [GO:0060124]; regulation of glutamate secretion [GO:0014048]; regulation of postsynaptic membrane potential [GO:0060078]; response to ethanol [GO:0045471]; response to nicotine [GO:0035094]; synaptic transmission, GABAergic [GO:0051932] GO:0001649; GO:0004888; GO:0004965; GO:0005615; GO:0005737; GO:0005789; GO:0005886; GO:0007186; GO:0007193; GO:0007194; GO:0007214; GO:0007268; GO:0008021; GO:0008285; GO:0014048; GO:0014049; GO:0014053; GO:0016020; GO:0030673; GO:0031966; GO:0032811; GO:0033602; GO:0035094; GO:0038037; GO:0038039; GO:0042734; GO:0043005; GO:0043025; GO:0043197; GO:0043198; GO:0043204; GO:0043231; GO:0045121; GO:0045211; GO:0045471; GO:0046982; GO:0050805; GO:0051932; GO:0060078; GO:0060124; GO:0097060; GO:0098685; GO:0098793; GO:0098978; GO:0098982; GO:0099565; GO:0099579; GO:0150047; GO:0150099; GO:1902710; GO:1902712; GO:1990430 32493 XM_044326690.1 383 169 602 885 92 NA NA NA NA NA NA 32494 XM_029351057.2 15 8 0 9 17 NA NA NA NA NA NA 32495 XM_029354455.2 616 548 453 610 944 NA NA NA NA NA NA 32496 XM_044319163.1 0 0 1 0 18 NA NA NA NA NA NA 32497 XM_029340746.2 489 219 244 943 1260 NA NA NA NA NA NA 32498 XM_044322828.1 11 0 0 5 14 NA NA NA NA NA NA 32499 XM_044319618.1 1 0 0 5 18 NA NA NA NA NA NA 32500 XM_044319639.1 18 15 16 16 77 NA NA NA NA NA NA 32501 XM_044317147.1 177 196 130 68 191 NA NA NA NA NA NA 32502 XM_044318257.1 1525 1066 980 1508 1149 E9Q634 0 Unconventional myosin-Ie (Unconventional myosin 1E) Mus musculus (Mouse) actin filament organization [GO:0007015]; endocytosis [GO:0006897]; glomerular basement membrane development [GO:0032836]; glomerular filtration [GO:0003094]; hemopoiesis [GO:0030097]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; nitrogen compound metabolic process [GO:0006807]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; podocyte development [GO:0072015]; post-embryonic hemopoiesis [GO:0035166]; vasculogenesis [GO:0001570]; vesicle transport along actin filament [GO:0030050] GO:0000146; GO:0001570; GO:0001701; GO:0001822; GO:0003094; GO:0005516; GO:0005524; GO:0005737; GO:0005856; GO:0005886; GO:0005902; GO:0005903; GO:0005912; GO:0006807; GO:0006897; GO:0007015; GO:0015629; GO:0016459; GO:0016887; GO:0030050; GO:0030097; GO:0031982; GO:0032437; GO:0032836; GO:0032991; GO:0035091; GO:0035166; GO:0044877; GO:0045334; GO:0048008; GO:0051015; GO:0072015 32503 XM_044327654.1 418 207 190 136 195 NA NA NA NA NA NA 32504 XM_029343267.2 4690 4749 3078 4749 3885 P22892 0 AP-1 complex subunit gamma-1 (Adaptor protein complex AP-1 subunit gamma-1) (Adaptor-related protein complex 1 subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain) (Gamma-adaptin) (Gamma1-adaptin) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1) Mus musculus (Mouse) basolateral protein secretion [GO:0110010]; endosome to melanosome transport [GO:0035646]; Golgi to lysosome transport [GO:0090160]; Golgi to vacuole transport [GO:0006896]; intracellular protein transport [GO:0006886]; melanosome assembly [GO:1903232]; platelet dense granule organization [GO:0060155]; positive regulation of natural killer cell degranulation [GO:0043323]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; vesicle-mediated transport [GO:0016192] GO:0005765; GO:0005769; GO:0005794; GO:0005802; GO:0005829; GO:0005905; GO:0006886; GO:0006896; GO:0016192; GO:0019894; GO:0030121; GO:0030136; GO:0030742; GO:0031267; GO:0032588; GO:0035615; GO:0035646; GO:0043231; GO:0043323; GO:0045954; GO:0048471; GO:0055037; GO:0060155; GO:0090160; GO:0110010; GO:0140312; GO:1903232 32505 XM_029343267.2 4690 4749 3078 4749 3885 P22892 4.64e-30 AP-1 complex subunit gamma-1 (Adaptor protein complex AP-1 subunit gamma-1) (Adaptor-related protein complex 1 subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain) (Gamma-adaptin) (Gamma1-adaptin) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1) Mus musculus (Mouse) basolateral protein secretion [GO:0110010]; endosome to melanosome transport [GO:0035646]; Golgi to lysosome transport [GO:0090160]; Golgi to vacuole transport [GO:0006896]; intracellular protein transport [GO:0006886]; melanosome assembly [GO:1903232]; platelet dense granule organization [GO:0060155]; positive regulation of natural killer cell degranulation [GO:0043323]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; vesicle-mediated transport [GO:0016192] GO:0005765; GO:0005769; GO:0005794; GO:0005802; GO:0005829; GO:0005905; GO:0006886; GO:0006896; GO:0016192; GO:0019894; GO:0030121; GO:0030136; GO:0030742; GO:0031267; GO:0032588; GO:0035615; GO:0035646; GO:0043231; GO:0043323; GO:0045954; GO:0048471; GO:0055037; GO:0060155; GO:0090160; GO:0110010; GO:0140312; GO:1903232 32506 XM_029343267.2 4690 4749 3078 4749 3885 P22892 4.64e-30 AP-1 complex subunit gamma-1 (Adaptor protein complex AP-1 subunit gamma-1) (Adaptor-related protein complex 1 subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain) (Gamma-adaptin) (Gamma1-adaptin) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1) Mus musculus (Mouse) basolateral protein secretion [GO:0110010]; endosome to melanosome transport [GO:0035646]; Golgi to lysosome transport [GO:0090160]; Golgi to vacuole transport [GO:0006896]; intracellular protein transport [GO:0006886]; melanosome assembly [GO:1903232]; platelet dense granule organization [GO:0060155]; positive regulation of natural killer cell degranulation [GO:0043323]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; vesicle-mediated transport [GO:0016192] GO:0005765; GO:0005769; GO:0005794; GO:0005802; GO:0005829; GO:0005905; GO:0006886; GO:0006896; GO:0016192; GO:0019894; GO:0030121; GO:0030136; GO:0030742; GO:0031267; GO:0032588; GO:0035615; GO:0035646; GO:0043231; GO:0043323; GO:0045954; GO:0048471; GO:0055037; GO:0060155; GO:0090160; GO:0110010; GO:0140312; GO:1903232 32507 XR_006395027.1 0 0 0 1 13 NA NA NA NA NA NA 32508 XR_006394955.1 58 48 41 57 63 NA NA NA NA NA NA 32509 XM_044308546.1 295 390 147 412 261 NA NA NA NA NA NA 32510 XM_044323397.1 479 583 429 293 354 Q9JM13 5.22e-104 Rab5 GDP/GTP exchange factor (Rabex-5) Mus musculus (Mouse) dendritic transport [GO:0098935]; establishment of localization in cell [GO:0051649]; Kit signaling pathway [GO:0038109]; mast cell degranulation [GO:0043303]; mast cell migration [GO:0097531]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of Kit signaling pathway [GO:1900235]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of mast cell activation [GO:0033004]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; negative regulation of receptor-mediated endocytosis [GO:0048261]; protein phosphorylation [GO:0006468]; protein targeting to membrane [GO:0006612]; Ras protein signal transduction [GO:0007265]; receptor-mediated endocytosis [GO:0006898]; regulation of Fc receptor mediated stimulatory signaling pathway [GO:0060368] GO:0001933; GO:0002686; GO:0003677; GO:0005085; GO:0005730; GO:0005769; GO:0005829; GO:0006468; GO:0006612; GO:0006898; GO:0007265; GO:0008270; GO:0030139; GO:0030425; GO:0031267; GO:0031982; GO:0032715; GO:0032764; GO:0033004; GO:0038109; GO:0043303; GO:0043305; GO:0046580; GO:0048261; GO:0050728; GO:0051649; GO:0055037; GO:0060368; GO:0061630; GO:0097531; GO:0098935; GO:1900235 32511 XM_029350760.2 2135 1318 1324 2362 2750 P51029 1.12e-73 Protein Wnt-8b Danio rerio (Zebrafish) (Brachydanio rerio) canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; commissural neuron axon guidance [GO:0071679]; embryonic pattern specification [GO:0009880]; eye development [GO:0001654]; eye field cell fate commitment involved in camera-type eye formation [GO:0060898]; forebrain development [GO:0030900]; forebrain neuron differentiation [GO:0021879]; hypothalamus development [GO:0021854]; negative regulation of anterior neural cell fate commitment of the neural plate by Wnt signaling pathway [GO:0022002]; neuron differentiation [GO:0030182]; otic placode formation [GO:0043049]; sensory epithelium regeneration [GO:0070654] GO:0001654; GO:0005109; GO:0005125; GO:0005615; GO:0009880; GO:0021854; GO:0021879; GO:0022002; GO:0030182; GO:0030900; GO:0043049; GO:0045165; GO:0060070; GO:0060898; GO:0070654; GO:0071679 32512 XR_003825543.2 20 19 20 9 52 NA NA NA NA NA NA 32513 XM_029346228.2 238 126 108 168 181 NA NA NA NA NA NA 32514 XM_029327090.2 369 332 256 298 309 Q5ZIG3 1.42e-88 Mitochondrial outer membrane protein SLC25A46 (Solute carrier family 25 member 46) Gallus gallus (Chicken) axon development [GO:0061564]; cristae formation [GO:0042407]; mitochondrial fission [GO:0000266]; mitochondrial membrane fission [GO:0090149]; phospholipid homeostasis [GO:0055091]; respiratory chain complex IV assembly [GO:0008535] GO:0000266; GO:0005741; GO:0008535; GO:0042407; GO:0044877; GO:0055091; GO:0061564; GO:0090149 32515 XM_044312226.1 152 0 260 138 69 NA NA NA NA NA NA 32516 XM_029332140.2 941 584 407 1107 945 Q6A028 1.97e-42 Switch-associated protein 70 (SWAP-70) Mus musculus (Mouse) actin filament bundle assembly [GO:0051017]; isotype switching [GO:0045190]; negative regulation of actin filament depolymerization [GO:0030835]; negative regulation of cell-cell adhesion mediated by integrin [GO:0033633]; negative regulation of peptidyl-serine dephosphorylation [GO:1902309]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of mast cell chemotaxis [GO:0060754]; regulation of actin polymerization or depolymerization [GO:0008064]; regulation of protein localization [GO:0032880]; somatic cell DNA recombination [GO:0016444] GO:0003677; GO:0005524; GO:0005634; GO:0005737; GO:0005886; GO:0007204; GO:0008064; GO:0015629; GO:0016444; GO:0030027; GO:0030835; GO:0032233; GO:0032880; GO:0033633; GO:0045190; GO:0051017; GO:0060754; GO:1902309 32517 XR_006393925.1 12 0 14 0 73 NA NA NA NA NA NA 32518 XM_044309282.1 46 1 42 110 56 NA NA NA NA NA NA 32519 XM_044320964.1 0 0 34 0 0 NA NA NA NA NA NA 32520 XM_029330962.2 40 48 43 60 76 Q9R1A9 6.5e-34 Three prime repair exonuclease 2 (EC 3.1.11.2) (3'-5' exonuclease TREX2) Mus musculus (Mouse) DNA catabolic process, exonucleolytic [GO:0000738]; DNA metabolic process [GO:0006259]; DNA repair [GO:0006281] GO:0000287; GO:0000738; GO:0003677; GO:0005634; GO:0005737; GO:0006259; GO:0006281; GO:0008296; GO:0008853; GO:0042803; GO:0060090 32521 XM_029340699.2 89 30 1717 29 1802 Q9Y4L5 8.6e-45 E3 ubiquitin-protein ligase RNF115 (EC 2.3.2.27) (RING finger protein 115) (RING-type E3 ubiquitin transferase RNF115) (Rab7-interacting RING finger protein) (Rabring 7) (Zinc finger protein 364) Homo sapiens (Human) negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] GO:0004842; GO:0005829; GO:0042059; GO:0043162; GO:0046872; GO:0051865; GO:0061630; GO:0070534; GO:0070936 32522 XR_006395240.1 856 563 512 827 868 NA NA NA NA NA NA 32523 XM_044325828.1 27 0 70 84 17 NA NA NA NA NA NA 32524 XR_006398141.1 0 3 9 28 5 NA NA NA NA NA NA 32525 XM_029342337.2 0 0 0 0 44 NA NA NA NA NA NA 32526 XM_029334210.2 4536 898 1135 3398 3336 NA NA NA NA NA NA 32527 XR_006395748.1 31 6 6 11 38 NA NA NA NA NA NA 32528 XM_044308130.1 7 8 45 30 13 NA NA NA NA NA NA 32529 XR_003824939.2 4 15 3 12 11 NA NA NA NA NA NA 32530 XM_044322108.1 25 6 2 8 2 Q5DTY9 2.62e-51 BTB/POZ domain-containing protein KCTD16 Mus musculus (Mouse) protein homooligomerization [GO:0051260]; regulation of G protein-coupled receptor signaling pathway [GO:0008277] GO:0008277; GO:0042734; GO:0042995; GO:0043235; GO:0045211; GO:0051260 32531 XM_044310816.1 44 40 38 40 50 NA NA NA NA NA NA 32532 XM_029345914.2 412 370 244 549 659 Q13188 0 Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) (MST-2) (STE20-like kinase MST2) (Serine/threonine-protein kinase Krs-1) [Cleaved into: Serine/threonine-protein kinase 3 36kDa subunit (MST2/N); Serine/threonine-protein kinase 3 20kDa subunit (MST2/C)] Homo sapiens (Human) apoptotic process [GO:0006915]; canonical Wnt signaling pathway [GO:0060070]; cell differentiation involved in embryonic placenta development [GO:0060706]; central nervous system development [GO:0007417]; endocardium development [GO:0003157]; epithelial cell proliferation [GO:0050673]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; hepatocyte apoptotic process [GO:0097284]; hippo signaling [GO:0035329]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of organ growth [GO:0046621]; neural tube formation [GO:0001841]; organ growth [GO:0035265]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein binding [GO:0032092]; positive regulation of protein kinase B signaling [GO:0051897]; primitive hemopoiesis [GO:0060215]; protein import into nucleus [GO:0006606]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; regulation of cell differentiation involved in embryonic placenta development [GO:0060800]; regulation of MAPK cascade [GO:0043408]; selective autophagy [GO:0061912]; signal transduction [GO:0007165] GO:0000287; GO:0001841; GO:0003157; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006468; GO:0006606; GO:0006915; GO:0007165; GO:0007254; GO:0007417; GO:0008625; GO:0032092; GO:0032991; GO:0035265; GO:0035329; GO:0035556; GO:0042802; GO:0043065; GO:0043408; GO:0043491; GO:0043539; GO:0045600; GO:0046330; GO:0046621; GO:0050673; GO:0050680; GO:0050821; GO:0051091; GO:0051262; GO:0051897; GO:0060070; GO:0060215; GO:0060706; GO:0060800; GO:0061912; GO:0090090; GO:0097284; GO:0106310; GO:1902043 32533 XR_006395066.1 191 135 104 152 225 NA NA NA NA NA NA 32534 XM_029351084.2 202 0 181 0 168 NA NA NA NA NA NA 32535 XM_044312203.1 62 21 0 35 158 NA NA NA NA NA NA 32536 XM_029357997.2 710 210 260 431 359 NA NA NA NA NA NA 32537 XM_044322593.1 10 0 0 5 0 C6KFA3 1.25e-22 Adhesion G-protein coupled receptor G6 (G-protein coupled receptor 126) [Cleaved into: ADGRG6 N-terminal fragment (ADGRG6-NTF); ADGRG6 C-terminal fragment (ADGRG6-CTF)] Danio rerio (Zebrafish) (Brachydanio rerio) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cAMP-mediated signaling [GO:0019933]; cell surface receptor signaling pathway [GO:0007166]; ear development [GO:0043583]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; heart trabecula formation [GO:0060347]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; myelination of posterior lateral line nerve axons [GO:0048932]; ossification [GO:0001503]; peripheral nervous system myelin formation [GO:0032290]; regulation of sprouting angiogenesis [GO:1903670]; Schwann cell differentiation [GO:0014037]; semicircular canal fusion [GO:0060879] GO:0001503; GO:0004930; GO:0005518; GO:0005886; GO:0007005; GO:0007166; GO:0007186; GO:0007189; GO:0007507; GO:0014037; GO:0019933; GO:0022011; GO:0032290; GO:0042552; GO:0043236; GO:0043583; GO:0048932; GO:0050840; GO:0060347; GO:0060879; GO:1903670 32538 XM_029350531.2 85 105 20 249 40 O42127 6.78e-59 Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) Xenopus laevis (African clawed frog) apoptotic process [GO:0006915]; positive regulation of cell population proliferation [GO:0008284] GO:0005007; GO:0005524; GO:0005886; GO:0006915; GO:0008284 32539 XM_044310980.1 4049 5940 2463 4157 3539 O42148 2.12e-26 Ornithine decarboxylase antizyme 1 (ODC-Az) Gallus gallus (Chicken) positive regulation of protein catabolic process [GO:0045732]; regulation of catalytic activity [GO:0050790] GO:0005634; GO:0005737; GO:0008073; GO:0045732; GO:0050790 32540 XM_044324872.1 278 197 289 143 835 Q9D379 4.66e-123 Epoxide hydrolase 1 (EC 3.3.2.9) (Epoxide hydratase) (Microsomal epoxide hydrolase) (mEH) Mus musculus (Mouse) arachidonic acid metabolic process [GO:0019369]; aromatic compound catabolic process [GO:0019439]; cellular aromatic compound metabolic process [GO:0006725]; cellular response to glucocorticoid stimulus [GO:0071385]; diol biosynthetic process [GO:0034312]; epoxide metabolic process [GO:0097176]; liver development [GO:0001889]; response to organic cyclic compound [GO:0014070]; response to toxic substance [GO:0009636] GO:0001889; GO:0004301; GO:0005789; GO:0005886; GO:0006725; GO:0009636; GO:0014070; GO:0016020; GO:0019369; GO:0019439; GO:0019899; GO:0033961; GO:0034312; GO:0043231; GO:0071385; GO:0097176 32541 XM_029327094.2 2085 1216 1198 2238 942 Q09225 3.88e-66 Nose resistant to fluoxetine protein 6 (Protein nrf-6) Caenorhabditis elegans lipid transport [GO:0006869] GO:0006869; GO:0008289; GO:0016020; GO:0016747 32542 XM_044322945.1 1409 1222 569 896 747 NA NA NA NA NA NA 32543 XM_044326053.1 10 34 38 24 29 NA NA NA NA NA NA 32544 XM_029339093.2 24 3 16 16 66 P27590 2.74e-33 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Rattus norvegicus (Rat) antibacterial innate immune response [GO:0140367]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; autophagy [GO:0006914]; calcium ion homeostasis [GO:0055074]; cellular calcium ion homeostasis [GO:0006874]; cellular chloride ion homeostasis [GO:0030644]; cellular phosphate ion homeostasis [GO:0030643]; cellular response to unfolded protein [GO:0034620]; cellular sodium ion homeostasis [GO:0006883]; chaperone-mediated protein folding [GO:0061077]; chemical homeostasis [GO:0048878]; chloride ion homeostasis [GO:0055064]; citric acid secretion [GO:0046720]; collecting duct development [GO:0072044]; connective tissue replacement [GO:0097709]; creatinine homeostasis [GO:0097273]; defense response to Gram-negative bacterium [GO:0050829]; endoplasmic reticulum organization [GO:0007029]; gene expression [GO:0010467]; glomerular filtration [GO:0003094]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; ion homeostasis [GO:0050801]; juxtaglomerular apparatus development [GO:0072051]; kidney development [GO:0001822]; leukocyte cell-cell adhesion [GO:0007159]; lipid metabolic process [GO:0006629]; loop of Henle development [GO:0072070]; metanephric ascending thin limb development [GO:0072218]; metanephric distal convoluted tubule development [GO:0072221]; metanephric thick ascending limb development [GO:0072233]; micturition [GO:0060073]; multicellular organismal homeostasis [GO:0048871]; multicellular organismal response to stress [GO:0033555]; neutrophil migration [GO:1990266]; organ or tissue specific immune response [GO:0002251]; peptidyl-threonine phosphorylation [GO:0018107]; phosphate ion homeostasis [GO:0055062]; potassium ion homeostasis [GO:0055075]; protein localization to vacuole [GO:0072665]; protein phosphorylation [GO:0006468]; protein transport into plasma membrane raft [GO:0044861]; regulation of blood pressure [GO:0008217]; regulation of protein transport [GO:0051223]; regulation of urine volume [GO:0035809]; renal sodium ion absorption [GO:0070294]; renal urate salt excretion [GO:0097744]; renal water homeostasis [GO:0003091]; response to endoplasmic reticulum stress [GO:0034976]; response to lipopolysaccharide [GO:0032496]; response to organic substance [GO:0010033]; response to unfolded protein [GO:0006986]; response to water deprivation [GO:0009414]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; sodium ion homeostasis [GO:0055078]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; ubiquitin-dependent ERAD pathway [GO:0030433]; urate transport [GO:0015747]; urea transmembrane transport [GO:0071918]; water homeostasis [GO:0030104] GO:0000922; GO:0001822; GO:0002251; GO:0003091; GO:0003094; GO:0005201; GO:0005509; GO:0005615; GO:0005783; GO:0005794; GO:0005886; GO:0005929; GO:0006468; GO:0006629; GO:0006874; GO:0006883; GO:0006914; GO:0006915; GO:0006954; GO:0006986; GO:0007029; GO:0007157; GO:0007159; GO:0008217; GO:0008380; GO:0009410; GO:0009414; GO:0009986; GO:0010033; GO:0010467; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0018107; GO:0019864; GO:0030104; GO:0030433; GO:0030643; GO:0030644; GO:0031410; GO:0032496; GO:0033209; GO:0033555; GO:0034620; GO:0034976; GO:0035809; GO:0044861; GO:0045121; GO:0045177; GO:0046720; GO:0048871; GO:0048878; GO:0050801; GO:0050829; GO:0051223; GO:0055062; GO:0055064; GO:0055074; GO:0055075; GO:0055078; GO:0060073; GO:0060170; GO:0061077; GO:0070294; GO:0071918; GO:0072044; GO:0072051; GO:0072070; GO:0072218; GO:0072221; GO:0072233; GO:0072665; GO:0097190; GO:0097273; GO:0097709; GO:0097744; GO:0140367; GO:1990266 32545 XR_006395915.1 5 0 0 0 9 NA NA NA NA NA NA 32546 XM_044323614.1 525 0 0 254 584 NA NA NA NA NA NA 32547 XM_044318998.1 159 127 27 104 23 Q5E9B3 2.98e-168 Geranylgeranyl transferase type-2 subunit beta (EC 2.5.1.60) (Geranylgeranyl transferase type II subunit beta) (GGTase-II-beta) (Rab geranyl-geranyltransferase subunit beta) (Rab GG transferase beta) (Rab GGTase beta) (Rab geranylgeranyltransferase subunit beta) (Type II protein geranyl-geranyltransferase subunit beta) Bos taurus (Bovine) protein geranylgeranylation [GO:0018344]; protein prenylation [GO:0018342] GO:0004663; GO:0005968; GO:0008270; GO:0018342; GO:0018344; GO:0031267 32548 XR_006396633.1 59 0 26 0 32 NA NA NA NA NA NA 32549 XM_044316496.1 951 343 72 1148 656 NA NA NA NA NA NA 32550 XM_044307351.1 38 11 9 89 24 NA NA NA NA NA NA 32551 XR_006395872.1 168 146 59 164 322 NA NA NA NA NA NA 32552 XM_029358133.2 143 111 85 95 94 Q5U2R1 3.61e-81 All trans-polyprenyl-diphosphate synthase PDSS2 (All-trans-decaprenyl-diphosphate synthase subunit 2) (EC 2.5.1.91) (Decaprenyl-diphosphate synthase subunit 2) (Solanesyl-diphosphate synthase subunit 2) Rattus norvegicus (Rat) cerebellum development [GO:0021549]; isoprenoid biosynthetic process [GO:0008299]; regulation of body fluid levels [GO:0050878]; ubiquinone biosynthetic process [GO:0006744] GO:0000010; GO:0004659; GO:0005739; GO:0005829; GO:0006744; GO:0008299; GO:0021549; GO:0046982; GO:0050878; GO:0052923; GO:0097269; GO:1990234 32553 XM_044319280.1 0 167 186 331 100 Q8TEP8 1.01e-152 Centrosomal protein of 192 kDa (Cep192) (Cep192/SPD-2) Homo sapiens (Human) centriole replication [GO:0007099]; centrosome-templated microtubule nucleation [GO:0090222]; mitotic spindle assembly [GO:0090307]; protein localization to centrosome [GO:0071539]; response to bacterium [GO:0009617] GO:0000242; GO:0005737; GO:0005813; GO:0005814; GO:0005829; GO:0007099; GO:0009617; GO:0019901; GO:0019902; GO:0071539; GO:0090222; GO:0090307; GO:0120098; GO:0120099 32554 XM_044318153.1 927 685 475 884 1011 Q13948 0 Protein CASP Homo sapiens (Human) intra-Golgi vesicle-mediated transport [GO:0006891] GO:0000139; GO:0005654; GO:0005794; GO:0006891 32555 XM_029356196.2 117 0 70 119 128 Q96A58 3.38e-33 Ras-related and estrogen-regulated growth inhibitor (EC 3.6.5.2) Homo sapiens (Human) negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; Ras protein signal transduction [GO:0007265]; response to hormone [GO:0009725]; small GTPase mediated signal transduction [GO:0007264] GO:0001650; GO:0003924; GO:0003925; GO:0005525; GO:0005634; GO:0005654; GO:0005829; GO:0005886; GO:0007264; GO:0007265; GO:0008285; GO:0009725; GO:0019003; GO:0030308; GO:0030331 32556 XM_044312815.1 0 0 28 0 10 NA NA NA NA NA NA 32557 XM_044307232.1 690 526 216 209 485 Q7M456 6.87e-33 Ribonuclease Oy (RNase Oy) (EC 3.1.27.-) Crassostrea gigas (Pacific oyster) (Crassostrea angulata) NA GO:0003723; GO:0005576; GO:0033897 32558 XM_044325810.1 50 39 29 78 80 NA NA NA NA NA NA 32559 XM_044319900.1 103 70 52 70 129 NA NA NA NA NA NA 32560 XM_029332068.2 384 373 159 345 302 NA NA NA NA NA NA 32561 XM_029326997.2 158 982 520 1005 2034 Q9NZI7 1.6e-100 Upstream-binding protein 1 (Transcription factor LBP-1) Homo sapiens (Human) angiogenesis [GO:0001525]; negative regulation of viral transcription [GO:0032897]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000785; GO:0000978; GO:0000981; GO:0001228; GO:0001525; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0032897; GO:0045944; GO:1990837 32562 XM_044324154.1 16 9 8 9 1 NA NA NA NA NA NA 32563 XM_029347157.2 0 427 265 388 803 O88427 0 Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage-gated calcium channel subunit alpha Cav3.2) Mus musculus (Mouse) aldosterone biosynthetic process [GO:0032342]; calcium ion import [GO:0070509]; calcium ion transport [GO:0006816]; cortisol biosynthetic process [GO:0034651]; inorganic cation transmembrane transport [GO:0098662]; membrane depolarization during action potential [GO:0086010]; neuronal action potential [GO:0019228]; positive regulation of acrosome reaction [GO:2000344]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of cardiac muscle cell contraction [GO:0106134]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; sensory perception of pain [GO:0019233] GO:0001518; GO:0005244; GO:0005248; GO:0005634; GO:0005737; GO:0005886; GO:0005891; GO:0005901; GO:0006816; GO:0008332; GO:0016020; GO:0019228; GO:0019233; GO:0030425; GO:0032342; GO:0034651; GO:0034765; GO:0042383; GO:0042391; GO:0043005; GO:0043204; GO:0045211; GO:0045956; GO:0046872; GO:0048787; GO:0070509; GO:0086010; GO:0097110; GO:0098662; GO:0098978; GO:0106134; GO:2000344 32564 XM_029347157.2 0 427 265 388 803 O88427 2.37e-88 Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage-gated calcium channel subunit alpha Cav3.2) Mus musculus (Mouse) aldosterone biosynthetic process [GO:0032342]; calcium ion import [GO:0070509]; calcium ion transport [GO:0006816]; cortisol biosynthetic process [GO:0034651]; inorganic cation transmembrane transport [GO:0098662]; membrane depolarization during action potential [GO:0086010]; neuronal action potential [GO:0019228]; positive regulation of acrosome reaction [GO:2000344]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of cardiac muscle cell contraction [GO:0106134]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; sensory perception of pain [GO:0019233] GO:0001518; GO:0005244; GO:0005248; GO:0005634; GO:0005737; GO:0005886; GO:0005891; GO:0005901; GO:0006816; GO:0008332; GO:0016020; GO:0019228; GO:0019233; GO:0030425; GO:0032342; GO:0034651; GO:0034765; GO:0042383; GO:0042391; GO:0043005; GO:0043204; GO:0045211; GO:0045956; GO:0046872; GO:0048787; GO:0070509; GO:0086010; GO:0097110; GO:0098662; GO:0098978; GO:0106134; GO:2000344 32565 XM_029336564.2 1724 1512 1334 1433 1225 Q7TPL3 1.95e-129 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 (BTB/POZ domain-containing protein KCTD10) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; heart development [GO:0007507]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of Rho protein signal transduction [GO:0035024]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0001525; GO:0005112; GO:0005634; GO:0006511; GO:0007507; GO:0016567; GO:0031463; GO:0035024; GO:0036038; GO:0042802; GO:0043161; GO:0045746; GO:0051260 32566 XM_044311140.1 82 0 0 0 7 NA NA NA NA NA NA 32567 XM_044329183.1 81 31 93 59 286 Q5XG58 1.21e-108 Elongator complex protein 4 Xenopus laevis (African clawed frog) regulation of transcription by RNA polymerase II [GO:0006357]; tRNA wobble uridine modification [GO:0002098] GO:0002098; GO:0005737; GO:0006357; GO:0008023; GO:0008607; GO:0033588 32568 XR_006394256.1 11 4 43 9 189 NA NA NA NA NA NA 32569 XM_029341968.2 115 87 66 87 138 A6NNA5 5.66e-26 Dorsal root ganglia homeobox protein (Paired-related homeobox protein-like 1) Homo sapiens (Human) axon guidance [GO:0007411]; detection of chemical stimulus [GO:0009593]; detection of temperature stimulus [GO:0016048]; dorsal spinal cord development [GO:0021516]; neuron migration [GO:0001764]; regulation of transcription by RNA polymerase II [GO:0006357]; sensory perception of mechanical stimulus [GO:0050954]; trigeminal nerve development [GO:0021559] GO:0000785; GO:0000977; GO:0000981; GO:0001764; GO:0005634; GO:0006357; GO:0007411; GO:0009593; GO:0016048; GO:0021516; GO:0021559; GO:0050954; GO:1990837 32570 XR_006393125.1 3 18 295 24 391 NA NA NA NA NA NA 32571 XM_029356580.2 2035 1915 1704 1463 871 NA NA NA NA NA NA 32572 XM_044325689.1 18 0 9 9 53 NA NA NA NA NA NA 32573 XM_029328641.2 4186 4393 2976 3783 3201 P28075 5.79e-124 Proteasome subunit beta type-5 (EC 3.4.25.1) (Macropain epsilon chain) (Multicatalytic endopeptidase complex epsilon chain) (Proteasome chain 6) (Proteasome epsilon chain) (Proteasome subunit X) Rattus norvegicus (Rat) proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; proteolysis [GO:0006508]; response to oxidative stress [GO:0006979] GO:0000502; GO:0004175; GO:0004298; GO:0005634; GO:0005737; GO:0005839; GO:0006508; GO:0006979; GO:0008233; GO:0010498; GO:0019774; GO:0043161 32574 XM_044325287.1 12 20 0 0 67 NA NA NA NA NA NA 32575 XM_029350597.2 19 16 19 23 31 NA NA NA NA NA NA 32576 XM_044309653.1 118 33 110 144 106 NA NA NA NA NA NA 32577 XM_029332855.2 1210 793 657 812 1166 P97767 5.71e-154 Eyes absent homolog 1 (EC 3.1.3.16) (EC 3.1.3.48) Mus musculus (Mouse) anatomical structure development [GO:0048856]; animal organ morphogenesis [GO:0009887]; aorta morphogenesis [GO:0035909]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chromatin organization [GO:0006325]; cochlea morphogenesis [GO:0090103]; double-strand break repair [GO:0006302]; embryonic skeletal system morphogenesis [GO:0048704]; epithelial cell proliferation [GO:0050673]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; inner ear morphogenesis [GO:0042472]; mesodermal cell fate specification [GO:0007501]; metanephros development [GO:0001656]; middle ear morphogenesis [GO:0042474]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; neuron fate specification [GO:0048665]; otic vesicle development [GO:0071599]; otic vesicle morphogenesis [GO:0071600]; outer ear morphogenesis [GO:0042473]; outflow tract morphogenesis [GO:0003151]; pattern specification process [GO:0007389]; pharyngeal system development [GO:0060037]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of secondary heart field cardioblast proliferation [GO:0072513]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein dephosphorylation [GO:0006470]; protein sumoylation [GO:0016925]; regulation of neuron differentiation [GO:0045664]; response to ionizing radiation [GO:0010212]; semicircular canal morphogenesis [GO:0048752]; striated muscle tissue development [GO:0014706]; ureteric bud development [GO:0001657] GO:0001656; GO:0001657; GO:0001658; GO:0003151; GO:0003723; GO:0004725; GO:0005634; GO:0005654; GO:0005737; GO:0006302; GO:0006325; GO:0006470; GO:0007389; GO:0007501; GO:0009887; GO:0010212; GO:0014706; GO:0016604; GO:0016925; GO:0017018; GO:0030154; GO:0032991; GO:0032993; GO:0035909; GO:0042472; GO:0042473; GO:0042474; GO:0045165; GO:0045664; GO:0045739; GO:0045893; GO:0045944; GO:0046872; GO:0048665; GO:0048704; GO:0048752; GO:0048856; GO:0050673; GO:0050679; GO:0060037; GO:0071599; GO:0071600; GO:0072513; GO:0090103; GO:0097192; GO:0140793; GO:2001240 32578 XR_006396669.1 0 0 0 0 12 NA NA NA NA NA NA 32579 XM_044324848.1 0 0 0 43 0 NA NA NA NA NA NA 32580 XM_044329082.1 23 22 12 1 17 NA NA NA NA NA NA 32581 XM_029353124.2 409 258 185 367 416 Q5XIB2 2.27e-127 Spliceosome-associated protein CWC27 homolog (Probable inactive peptidyl-prolyl cis-trans isomerase CWC27 homolog) (PPIase CWC27) Rattus norvegicus (Rat) protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413] GO:0000413; GO:0005634; GO:0006457; GO:0071005; GO:0071013 32582 XR_006397872.1 108 23 0 0 13 NA NA NA NA NA NA 32583 XM_044312819.1 14 81 68 20 3 Q9NPC2 2.36e-28 Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3) (Two pore potassium channel KT3.2) (Two pore K(+) channel KT3.2) Homo sapiens (Human) potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; stabilization of membrane potential [GO:0030322] GO:0005267; GO:0005886; GO:0006813; GO:0008021; GO:0015271; GO:0022841; GO:0030322; GO:0071805; GO:1990573 32584 XM_044319577.1 82 55 40 74 44 NA NA NA NA NA NA 32585 XR_006393017.1 223 510 153 187 169 NA NA NA NA NA NA 32586 XM_029356296.2 819 484 354 574 728 Q80UY1 2.49e-130 Carnosine N-methyltransferase (EC 2.1.1.22) Mus musculus (Mouse) carnosine metabolic process [GO:0035498]; methylation [GO:0032259] GO:0005634; GO:0005829; GO:0008757; GO:0030735; GO:0032259; GO:0035498; GO:0042803 32587 XR_003824353.2 0 7 0 1 0 NA NA NA NA NA NA 32588 XM_044307064.1 318 33 205 181 368 Q7RTR2 6e-76 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 32589 XM_044307064.1 318 33 205 181 368 Q7RTR2 3.38e-75 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 32590 XM_044307064.1 318 33 205 181 368 Q7RTR2 3.27e-71 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 32591 XM_044307064.1 318 33 205 181 368 Q7RTR2 4.8e-55 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 32592 XM_029332570.2 54 59 34 79 97 NA NA NA NA NA NA 32593 XM_029338217.2 1653 1097 822 1229 1392 Q5R4T3 1.62e-36 Myeloid leukemia factor 1 (Myelodysplasia-myeloid leukemia factor 1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cell cycle [GO:0007049]; DNA-templated transcription [GO:0006351]; myeloid progenitor cell differentiation [GO:0002318]; regulation of cell cycle G1/S phase transition [GO:1902806] GO:0002318; GO:0003677; GO:0005634; GO:0005737; GO:0005929; GO:0006351; GO:0007049; GO:0036064; GO:1902806 32594 XR_003825532.2 632 450 387 590 615 NA NA NA NA NA NA 32595 XM_044318276.1 154 25 134 82 227 NA NA NA NA NA NA 32596 XM_044315039.1 9 43 0 0 0 NA NA NA NA NA NA 32597 XM_044322919.1 12 0 0 13 21 NA NA NA NA NA NA 32598 XR_003825156.2 12 4 0 6 5 NA NA NA NA NA NA 32599 XM_029343014.2 286 243 114 103 83 Q6P2K6 0 Serine/threonine-protein phosphatase 4 regulatory subunit 3A (SMEK homolog 1) Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; gluconeogenesis [GO:0006094]; positive regulation of gluconeogenesis [GO:0045722]; protein dephosphorylation [GO:0006470] GO:0005634; GO:0005654; GO:0005737; GO:0005815; GO:0005829; GO:0006094; GO:0006470; GO:0006974; GO:0016607; GO:0030289; GO:0045722; GO:0072542 32600 XM_029333660.2 1761 1356 560 1018 810 Q9V576 3.11e-47 Putative phosphatidate phosphatase (EC 3.1.3.4) (Germ cell guidance factor) (Phosphatidic acid phosphatase type 2) (Protein wunen) Drosophila melanogaster (Fruit fly) defense response to Gram-negative bacterium [GO:0050829]; ectopic germ cell programmed cell death [GO:0035234]; germ cell migration [GO:0008354]; germ cell repulsion [GO:0035233]; negative regulation of innate immune response [GO:0045824]; open tracheal system development [GO:0007424]; phospholipid dephosphorylation [GO:0046839]; phospholipid metabolic process [GO:0006644]; pole cell migration [GO:0007280]; septate junction assembly [GO:0019991]; signal transduction [GO:0007165] GO:0005886; GO:0005918; GO:0006644; GO:0007165; GO:0007280; GO:0007424; GO:0008195; GO:0008354; GO:0016791; GO:0019991; GO:0035233; GO:0035234; GO:0042577; GO:0045177; GO:0045824; GO:0046839; GO:0050829 32601 XM_029336711.2 0 2 5 0 38 NA NA NA NA NA NA 32602 XM_029357432.2 602 417 509 508 508 Q69Z66 4.44e-109 Deubiquitinase MYSM1 (2A-DUB) (EC 3.4.19.-) (Myb-like, SWIRM and MPN domain-containing protein 1) Mus musculus (Mouse) chromatin remodeling [GO:0006338]; immune system process [GO:0002376]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; pigmentation [GO:0043473]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell migration [GO:0030334]; regulation of hair follicle development [GO:0051797]; regulation of hemopoiesis [GO:1903706] GO:0002376; GO:0003677; GO:0003713; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0006338; GO:0030334; GO:0032991; GO:0035522; GO:0042393; GO:0043473; GO:0045944; GO:0046872; GO:0051797; GO:0140492; GO:1903706 32603 XM_044312417.1 16 4 0 7 0 NA NA NA NA NA NA 32604 XM_029353178.2 16 30 15 23 66 NA NA NA NA NA NA 32605 XM_029351327.2 0 38 29 92 33 Q924V1 6.37e-130 NADPH oxidase 4 (EC 1.6.3.-) (Kidney oxidase-1) (KOX-1) (Kidney superoxide-producing NADPH oxidase) Rattus norvegicus (Rat) aging [GO:0007568]; bone resorption [GO:0045453]; cardiac muscle cell differentiation [GO:0055007]; cell morphogenesis [GO:0000902]; cellular response to cAMP [GO:0071320]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose stimulus [GO:0071333]; cellular response to transforming growth factor beta stimulus [GO:0071560]; defense response [GO:0006952]; gene expression [GO:0010467]; heart process [GO:0003015]; homocysteine metabolic process [GO:0050667]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hydrogen peroxide biosynthetic process [GO:0010729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of stress fiber assembly [GO:0051496]; reactive oxygen species metabolic process [GO:0072593]; response to hypoxia [GO:0001666]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801] GO:0000902; GO:0001666; GO:0003015; GO:0005634; GO:0005739; GO:0005789; GO:0005886; GO:0005925; GO:0006801; GO:0006952; GO:0007568; GO:0008285; GO:0010467; GO:0010729; GO:0014911; GO:0016174; GO:0016175; GO:0016324; GO:0042554; GO:0043020; GO:0043065; GO:0043406; GO:0045453; GO:0048471; GO:0050664; GO:0050667; GO:0051496; GO:0051897; GO:0055007; GO:0061098; GO:0070374; GO:0071320; GO:0071333; GO:0071480; GO:0071560; GO:0071944; GO:0072341; GO:0072593; GO:0097038; GO:1990782; GO:2000379; GO:2000573 32606 XM_029336042.2 535 278 322 498 451 Q9CR92 7.41e-68 Coiled-coil domain-containing protein 96 Mus musculus (Mouse) cilium assembly [GO:0060271] GO:0005930; GO:0036064; GO:0060271 32607 XM_029333288.2 2268 1640 1218 2366 2300 O43586 1.74e-78 Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP) Homo sapiens (Human) actin filament polymerization [GO:0030041]; cell adhesion [GO:0007155]; endocytosis [GO:0006897]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; signal transduction [GO:0007165] GO:0001931; GO:0005737; GO:0005829; GO:0005884; GO:0005886; GO:0006897; GO:0006954; GO:0007155; GO:0007165; GO:0016020; GO:0030027; GO:0030041; GO:0032154; GO:0042802; GO:0045087; GO:0048471; GO:0051015 32608 XM_029345718.2 31 28 21 18 10 NA NA NA NA NA NA 32609 XM_044327227.1 0 28 126 0 180 Q4V348 1.59e-117 Zinc finger protein 658B Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 32610 XM_044327227.1 0 28 126 0 180 Q4V348 6.78e-110 Zinc finger protein 658B Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 32611 XM_044327227.1 0 28 126 0 180 Q4V348 8.1e-108 Zinc finger protein 658B Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 32612 XM_044327227.1 0 28 126 0 180 Q4V348 1.26e-105 Zinc finger protein 658B Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 32613 XM_044327227.1 0 28 126 0 180 Q4V348 5.79e-87 Zinc finger protein 658B Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 32614 XM_044327227.1 0 28 126 0 180 Q4V348 4.87e-77 Zinc finger protein 658B Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 32615 XM_044327227.1 0 28 126 0 180 Q4V348 1.81e-70 Zinc finger protein 658B Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 32616 XM_029328959.2 316 232 148 319 185 Q8VDU0 2.8e-27 G-protein-signaling modulator 2 (Pins homolog) Mus musculus (Mouse) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 32617 XM_044310634.1 9 1 56 15 46 NA NA NA NA NA NA 32618 XM_029329244.2 32496 33146 28044 33737 26198 NA NA NA NA NA NA 32619 XM_044307888.1 0 4 10 0 10 P04323 2.49e-42 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 32620 XM_044328766.1 104 23 37 27 150 NA NA NA NA NA NA 32621 XM_044314149.1 1 11 0 0 18 NA NA NA NA NA NA 32622 XM_029350491.2 0 170 42 53 181 Q5C9Z4 7.5e-159 Nucleolar MIF4G domain-containing protein 1 (SGD1 homolog) Homo sapiens (Human) hair follicle maturation [GO:0048820]; ribosomal small subunit biogenesis [GO:0042274] GO:0003723; GO:0005730; GO:0042274; GO:0048820 32623 XM_029342420.2 426 418 132 403 459 O60930 1.71e-65 Ribonuclease H1 (RNase H1) (EC 3.1.26.4) (Ribonuclease H type II) Homo sapiens (Human) DNA replication, removal of RNA primer [GO:0043137]; RNA catabolic process [GO:0006401]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502] GO:0000287; GO:0003676; GO:0003723; GO:0004523; GO:0004540; GO:0005737; GO:0006401; GO:0043137; GO:0090502 32624 XM_044328187.1 4823 2006 725 2551 1296 NA NA NA NA NA NA 32625 XM_029334508.2 1399 541 703 1061 966 NA NA NA NA NA NA 32626 XM_029348130.2 1005 1399 472 847 908 P58058 1.28e-127 NAD kinase (EC 2.7.1.23) (Poly(P)/ATP NAD kinase) Mus musculus (Mouse) NAD metabolic process [GO:0019674]; NADP biosynthetic process [GO:0006741]; phosphorylation [GO:0016310]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774] GO:0003951; GO:0005524; GO:0005829; GO:0006741; GO:0016310; GO:0019674; GO:0035774; GO:0046872 32627 XM_029340954.2 162 242 225 87 134 P57054 1.9e-39 Phosphatidylinositol N-acetylglucosaminyltransferase subunit P (Down syndrome critical region protein 5) (Down syndrome critical region protein C) (Phosphatidylinositol-glycan biosynthesis class P protein) (PIG-P) Homo sapiens (Human) GPI anchor biosynthetic process [GO:0006506] GO:0000506; GO:0005783; GO:0005789; GO:0006506; GO:0017176 32628 XM_029340569.2 274 294 255 224 310 Q9D8U2 1.66e-73 Transmembrane protein 41A Mus musculus (Mouse) NA GO:0016020 32629 XM_029354469.2 542 167 224 460 403 NA NA NA NA NA NA 32630 XM_044324984.1 5 0 0 11 93 NA NA NA NA NA NA 32631 XM_029349670.2 1206 857 650 1273 1205 P49139 4.66e-154 MAP kinase-activated protein kinase 2 (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAP-K2) (MAPKAPK-2) (MK-2) (MK2) (EC 2.7.11.1) Oryctolagus cuniculus (Rabbit) 3'-UTR-mediated mRNA stabilization [GO:0070935]; cellular response to DNA damage stimulus [GO:0006974]; inflammatory response [GO:0006954]; macropinocytosis [GO:0044351]; protein phosphorylation [GO:0006468]; regulation of interleukin-6 production [GO:0032675]; regulation of tumor necrosis factor production [GO:0032680]; response to cytokine [GO:0034097]; response to lipopolysaccharide [GO:0032496]; toll-like receptor signaling pathway [GO:0002224] GO:0002224; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0006468; GO:0006954; GO:0006974; GO:0032496; GO:0032675; GO:0032680; GO:0034097; GO:0044351; GO:0070935; GO:0106310 32632 XM_044312863.1 476 313 235 507 554 Q8CJB9 1.4e-125 E3 ubiquitin-protein ligase BRE1B (BRE1-B) (EC 2.3.2.27) (RING finger protein 40) (RING-type E3 ubiquitin transferase BRE1B) (Syntaxin-1-interacting RING finger protein) (Protein staring) Rattus norvegicus (Rat) chromatin organization [GO:0006325]; histone H2B conserved C-terminal lysine ubiquitination [GO:0071894]; histone H2B ubiquitination [GO:0033523]; histone monoubiquitination [GO:0010390]; negative regulation of mRNA polyadenylation [GO:1900364]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein polyubiquitination [GO:1902916]; response to peptide hormone [GO:0043434]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000151; GO:0003730; GO:0004842; GO:0005634; GO:0005654; GO:0006325; GO:0006511; GO:0010390; GO:0016020; GO:0017075; GO:0031624; GO:0031625; GO:0032991; GO:0033503; GO:0033523; GO:0042803; GO:0043434; GO:0046872; GO:0061630; GO:0071894; GO:1900364; GO:1901800; GO:1902916; GO:2001168 32633 XM_044312863.1 476 313 235 507 554 Q8CJB9 2.43e-60 E3 ubiquitin-protein ligase BRE1B (BRE1-B) (EC 2.3.2.27) (RING finger protein 40) (RING-type E3 ubiquitin transferase BRE1B) (Syntaxin-1-interacting RING finger protein) (Protein staring) Rattus norvegicus (Rat) chromatin organization [GO:0006325]; histone H2B conserved C-terminal lysine ubiquitination [GO:0071894]; histone H2B ubiquitination [GO:0033523]; histone monoubiquitination [GO:0010390]; negative regulation of mRNA polyadenylation [GO:1900364]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein polyubiquitination [GO:1902916]; response to peptide hormone [GO:0043434]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000151; GO:0003730; GO:0004842; GO:0005634; GO:0005654; GO:0006325; GO:0006511; GO:0010390; GO:0016020; GO:0017075; GO:0031624; GO:0031625; GO:0032991; GO:0033503; GO:0033523; GO:0042803; GO:0043434; GO:0046872; GO:0061630; GO:0071894; GO:1900364; GO:1901800; GO:1902916; GO:2001168 32634 XM_029356122.2 1027 489 359 371 291 NA NA NA NA NA NA 32635 XR_006394306.1 17 0 51 60 79 NA NA NA NA NA NA 32636 XM_029326930.2 65 0 119 129 0 Q90268 2.17e-58 Paired box protein Pax-2a (No isthmus protein) (Pax[Zf-b]) Danio rerio (Zebrafish) (Brachydanio rerio) anatomical structure development [GO:0048856]; anterior/posterior pattern specification [GO:0009952]; anterior/posterior pattern specification involved in pronephros development [GO:0034672]; cell fate specification [GO:0001708]; cerebellum development [GO:0021549]; cerebellum formation [GO:0021588]; cilium assembly [GO:0060271]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic pattern specification [GO:0009880]; hindbrain development [GO:0030902]; inner ear receptor cell differentiation [GO:0060113]; kidney development [GO:0001822]; locus ceruleus development [GO:0021703]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; nervous system development [GO:0007399]; otic placode formation [GO:0043049]; peripheral nervous system development [GO:0007422]; pronephric glomerulus morphogenesis [GO:0035775]; pronephros development [GO:0048793]; pronephros morphogenesis [GO:0072114]; regulation of transcription by RNA polymerase II [GO:0006357]; thyroid gland development [GO:0030878]; vestibular receptor cell development [GO:0060118] GO:0000978; GO:0000981; GO:0001708; GO:0001822; GO:0003677; GO:0003700; GO:0005634; GO:0006357; GO:0007399; GO:0007422; GO:0009880; GO:0009952; GO:0021549; GO:0021588; GO:0021703; GO:0030878; GO:0030901; GO:0030902; GO:0030917; GO:0034672; GO:0035775; GO:0043049; GO:0043565; GO:0048596; GO:0048793; GO:0048856; GO:0060113; GO:0060118; GO:0060271; GO:0072114 32637 XM_029351875.2 559 888 339 426 258 NA NA NA NA NA NA 32638 XM_044317749.1 20 9 0 125 2 NA NA NA NA NA NA 32639 XM_044323138.1 22 32 17 26 29 NA NA NA NA NA NA 32640 XR_006396568.1 1813 1238 1102 1694 1878 NA NA NA NA NA NA 32641 XM_044307869.1 2453 1633 482 3904 1645 P23468 0 Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48) Homo sapiens (Human) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; neuron differentiation [GO:0030182]; phosphate-containing compound metabolic process [GO:0006796]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse assembly [GO:0051965]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; regulation of immune response [GO:0050776]; regulation of postsynaptic density assembly [GO:0099151]; synaptic membrane adhesion [GO:0099560]; trans-synaptic signaling by trans-synaptic complex [GO:0099545]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185] GO:0004725; GO:0005001; GO:0005102; GO:0005886; GO:0006470; GO:0006796; GO:0007157; GO:0007185; GO:0030182; GO:0042734; GO:0046426; GO:0050775; GO:0050776; GO:0050804; GO:0050839; GO:0051965; GO:0070062; GO:0097105; GO:0098685; GO:0098686; GO:0098978; GO:0099054; GO:0099151; GO:0099545; GO:0099560 32642 XM_044307869.1 2453 1633 482 3904 1645 P23468 6.59e-73 Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48) Homo sapiens (Human) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; neuron differentiation [GO:0030182]; phosphate-containing compound metabolic process [GO:0006796]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse assembly [GO:0051965]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; regulation of immune response [GO:0050776]; regulation of postsynaptic density assembly [GO:0099151]; synaptic membrane adhesion [GO:0099560]; trans-synaptic signaling by trans-synaptic complex [GO:0099545]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185] GO:0004725; GO:0005001; GO:0005102; GO:0005886; GO:0006470; GO:0006796; GO:0007157; GO:0007185; GO:0030182; GO:0042734; GO:0046426; GO:0050775; GO:0050776; GO:0050804; GO:0050839; GO:0051965; GO:0070062; GO:0097105; GO:0098685; GO:0098686; GO:0098978; GO:0099054; GO:0099151; GO:0099545; GO:0099560 32643 XM_044307869.1 2453 1633 482 3904 1645 P23468 1.7e-64 Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48) Homo sapiens (Human) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; neuron differentiation [GO:0030182]; phosphate-containing compound metabolic process [GO:0006796]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse assembly [GO:0051965]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; regulation of immune response [GO:0050776]; regulation of postsynaptic density assembly [GO:0099151]; synaptic membrane adhesion [GO:0099560]; trans-synaptic signaling by trans-synaptic complex [GO:0099545]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185] GO:0004725; GO:0005001; GO:0005102; GO:0005886; GO:0006470; GO:0006796; GO:0007157; GO:0007185; GO:0030182; GO:0042734; GO:0046426; GO:0050775; GO:0050776; GO:0050804; GO:0050839; GO:0051965; GO:0070062; GO:0097105; GO:0098685; GO:0098686; GO:0098978; GO:0099054; GO:0099151; GO:0099545; GO:0099560 32644 XM_044307869.1 2453 1633 482 3904 1645 P23468 8.5e-57 Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48) Homo sapiens (Human) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; neuron differentiation [GO:0030182]; phosphate-containing compound metabolic process [GO:0006796]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse assembly [GO:0051965]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; regulation of immune response [GO:0050776]; regulation of postsynaptic density assembly [GO:0099151]; synaptic membrane adhesion [GO:0099560]; trans-synaptic signaling by trans-synaptic complex [GO:0099545]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185] GO:0004725; GO:0005001; GO:0005102; GO:0005886; GO:0006470; GO:0006796; GO:0007157; GO:0007185; GO:0030182; GO:0042734; GO:0046426; GO:0050775; GO:0050776; GO:0050804; GO:0050839; GO:0051965; GO:0070062; GO:0097105; GO:0098685; GO:0098686; GO:0098978; GO:0099054; GO:0099151; GO:0099545; GO:0099560 32645 XM_044307869.1 2453 1633 482 3904 1645 P23468 4.72e-45 Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48) Homo sapiens (Human) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; neuron differentiation [GO:0030182]; phosphate-containing compound metabolic process [GO:0006796]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse assembly [GO:0051965]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; regulation of immune response [GO:0050776]; regulation of postsynaptic density assembly [GO:0099151]; synaptic membrane adhesion [GO:0099560]; trans-synaptic signaling by trans-synaptic complex [GO:0099545]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185] GO:0004725; GO:0005001; GO:0005102; GO:0005886; GO:0006470; GO:0006796; GO:0007157; GO:0007185; GO:0030182; GO:0042734; GO:0046426; GO:0050775; GO:0050776; GO:0050804; GO:0050839; GO:0051965; GO:0070062; GO:0097105; GO:0098685; GO:0098686; GO:0098978; GO:0099054; GO:0099151; GO:0099545; GO:0099560 32646 XM_044312736.1 0 0 0 0 14 Q8BRH0 1.28e-100 Protein O-mannosyl-transferase TMTC3 (EC 2.4.1.109) (Transmembrane and TPR repeat-containing protein 3) Mus musculus (Mouse) bud outgrowth involved in lung branching [GO:0060447]; cell differentiation [GO:0030154]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; muscle cell development [GO:0055001]; positive regulation of proteasomal protein catabolic process [GO:1901800]; post-embryonic development [GO:0009791]; protein O-linked mannosylation [GO:0035269]; regulation of gene expression [GO:0010468]; response to endoplasmic reticulum stress [GO:0034976] GO:0000030; GO:0004169; GO:0005783; GO:0009791; GO:0010468; GO:0016020; GO:0030154; GO:0030324; GO:0034976; GO:0035269; GO:0048286; GO:0055001; GO:0060447; GO:1901800 32647 XM_044314013.1 0 1 0 0 10 NA NA NA NA NA NA 32648 XM_029329541.2 2 13 12 0 0 P30974 1.58e-30 Tachykinin-like peptides receptor 86C (NKD) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; inter-male aggressive behavior [GO:0002121]; neuropeptide signaling pathway [GO:0007218]; tachykinin receptor signaling pathway [GO:0007217] GO:0002121; GO:0004995; GO:0005886; GO:0007186; GO:0007217; GO:0007218; GO:0008188; GO:0016020 32649 XM_044323389.1 349 192 259 0 150 A4D1E9 1.84e-63 GTP-binding protein 10 (Protein obg homolog 2) (ObgH2) Homo sapiens (Human) ribosome biogenesis [GO:0042254] GO:0000287; GO:0003723; GO:0003924; GO:0005525; GO:0005694; GO:0005730; GO:0005739; GO:0042254 32650 XM_044325783.1 0 16 2 14 44 Q5ZIJ9 1.9e-74 E3 ubiquitin-protein ligase MIB2 (EC 2.3.2.27) (Mind bomb homolog 2) (RING-type E3 ubiquitin transferase MIB2) Gallus gallus (Chicken) Notch signaling pathway [GO:0007219]; protein ubiquitination [GO:0016567] GO:0004842; GO:0005737; GO:0007219; GO:0008270; GO:0016567 32651 XM_029331348.2 18258 13475 11883 13024 8234 NA NA NA NA NA NA 32652 XR_006397891.1 1 45 16 21 26 NA NA NA NA NA NA 32653 XM_044313904.1 8 15 249 312 257 NA NA NA NA NA NA 32654 XM_044317633.1 22 0 0 69 0 Q5RHH4 0 Intraflagellar transport protein 172 homolog Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; intraciliary transport [GO:0042073]; photoreceptor cell maintenance [GO:0045494]; pronephros development [GO:0048793]; regulation of TOR signaling [GO:0032006]; retina development in camera-type eye [GO:0060041] GO:0005929; GO:0005930; GO:0030992; GO:0032006; GO:0036064; GO:0042073; GO:0045494; GO:0048793; GO:0060041; GO:0060271 32655 XM_029356213.2 97 70 29 50 0 Q8R367 1.05e-30 Ras-related and estrogen-regulated growth inhibitor (EC 3.6.5.2) Mus musculus (Mouse) negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; Ras protein signal transduction [GO:0007265]; response to hormone [GO:0009725] GO:0001650; GO:0003924; GO:0003925; GO:0005525; GO:0005634; GO:0005654; GO:0005829; GO:0005886; GO:0007265; GO:0008285; GO:0009725; GO:0019003; GO:0030308 32656 XM_029349958.2 490 438 350 314 614 F1M0Z1 1.96e-71 Triple functional domain protein (EC 2.7.11.1) (PTPRF-interacting protein) Rattus norvegicus (Rat) axon guidance [GO:0007411]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of fat cell differentiation [GO:0045599]; neuron projection morphogenesis [GO:0048812]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; protein phosphorylation [GO:0006468] GO:0004674; GO:0005085; GO:0005524; GO:0005737; GO:0006468; GO:0007411; GO:0019898; GO:0019899; GO:0042995; GO:0045599; GO:0048786; GO:0048812; GO:0050804; GO:0098685; GO:0098794; GO:0098978; GO:0099170; GO:0106310 32657 XM_029349958.2 490 438 350 314 614 F1M0Z1 1.59e-53 Triple functional domain protein (EC 2.7.11.1) (PTPRF-interacting protein) Rattus norvegicus (Rat) axon guidance [GO:0007411]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of fat cell differentiation [GO:0045599]; neuron projection morphogenesis [GO:0048812]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; protein phosphorylation [GO:0006468] GO:0004674; GO:0005085; GO:0005524; GO:0005737; GO:0006468; GO:0007411; GO:0019898; GO:0019899; GO:0042995; GO:0045599; GO:0048786; GO:0048812; GO:0050804; GO:0098685; GO:0098794; GO:0098978; GO:0099170; GO:0106310 32658 XM_029334905.2 280 1552 624 1541 1878 D3ZSZ3 0 Serine/threonine-protein kinase NLK (EC 2.7.11.24) (Nemo-like kinase) Rattus norvegicus (Rat) intracellular signal transduction [GO:0035556]; negative regulation of Wnt signaling pathway [GO:0030178]; peptidyl-threonine phosphorylation [GO:0018107]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of DNA-templated transcription [GO:0006355]; serine phosphorylation of STAT protein [GO:0042501]; transforming growth factor beta receptor signaling pathway [GO:0007179]; Wnt signaling pathway [GO:0016055] GO:0000287; GO:0004672; GO:0004674; GO:0004707; GO:0005524; GO:0005634; GO:0005737; GO:0006355; GO:0006468; GO:0007179; GO:0016055; GO:0018107; GO:0030178; GO:0031625; GO:0035556; GO:0042169; GO:0042501; GO:0046777; GO:0050821; GO:0106310; GO:0140297 32659 XM_029357710.2 2937 2931 1798 3433 955 NA NA NA NA NA NA 32660 XM_029353555.2 463 139 262 203 232 Q9N126 3.35e-68 Retinol dehydrogenase 8 (EC 1.1.1.300) (Photoreceptor outer segment all-trans retinol dehydrogenase) Bos taurus (Bovine) estrogen biosynthetic process [GO:0006703]; response to stimulus [GO:0050896]; retinol metabolic process [GO:0042572]; visual perception [GO:0007601] GO:0004303; GO:0004745; GO:0005829; GO:0006703; GO:0007601; GO:0016491; GO:0042572; GO:0042622; GO:0050896; GO:0052650 32661 XM_029331514.2 3244 3271 1430 3120 1192 NA NA NA NA NA NA 32662 XM_029324274.2 82 59 62 96 212 NA NA NA NA NA NA 32663 XM_044308068.1 126 0 0 169 246 Q8BQH6 1.22e-22 CUB domain-containing protein 2 Mus musculus (Mouse) NA GO:0005576 32664 XM_044318390.1 35 19 53 27 26 NA NA NA NA NA NA 32665 XM_044308808.1 779 706 298 318 363 NA NA NA NA NA NA 32666 XM_044321714.1 0 3204 2397 4064 3928 Q6AYC8 1.24e-36 SH2 domain-containing protein 4A Rattus norvegicus (Rat) NA GO:0005737; GO:0005829; GO:0019902 32667 XM_044329239.1 0 0 12 0 0 NA NA NA NA NA NA 32668 XM_029355166.2 111 63 0 21 3 Q9BX84 1.12e-21 Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6) Homo sapiens (Human) calcium ion transmembrane transport [GO:0070588]; cation transmembrane transport [GO:0098655]; protein phosphorylation [GO:0006468]; protein tetramerization [GO:0051262]; response to toxic substance [GO:0009636] GO:0004674; GO:0005261; GO:0005262; GO:0005524; GO:0005886; GO:0006468; GO:0009636; GO:0016324; GO:0031526; GO:0046872; GO:0051262; GO:0070588; GO:0098655; GO:0106310 32669 XM_044312964.1 12 30 32 461 49 NA NA NA NA NA NA 32670 XM_044308034.1 0 0 0 6 43 NA NA NA NA NA NA 32671 XM_029344132.2 65 405 50 78 101 P02720 3.19e-69 Phosphatidylcholine transfer protein (PC-TP) (START domain-containing protein 2) (StARD2) (StAR-related lipid transfer protein 2) Bos taurus (Bovine) phospholipid transport [GO:0015914] GO:0005737; GO:0008525; GO:0015914; GO:0031210 32672 XM_044323265.1 13 0 38 239 191 NA NA NA NA NA NA 32673 XM_029335054.2 1 0 22 10 38 NA NA NA NA NA NA 32674 XM_029340097.2 606 540 501 690 887 Q4FZQ6 6.37e-94 Pre-mRNA-splicing factor 38A Xenopus laevis (African clawed frog) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0005634; GO:0071005 32675 XM_029344825.2 15864 21952 10074 10485 14262 Q5RBA4 4.37e-74 Myosin regulatory light polypeptide 9 (Myosin regulatory light chain 2, smooth muscle isoform) (Myosin regulatory light chain 9) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0005509; GO:0005938; GO:0016459 32676 XM_044321737.1 10 1 0 0 8 O54853 4.45e-106 Potassium voltage-gated channel subfamily H member 6 (Ether-a-go-go-related gene potassium channel 2) (ERG-2) (Eag-related protein 2) (Ether-a-go-go-related protein 2) (Voltage-gated potassium channel subunit Kv11.2) Rattus norvegicus (Rat) membrane repolarization during action potential [GO:0086011]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307] GO:0005242; GO:0005249; GO:0005267; GO:0005886; GO:0006813; GO:0034765; GO:0042391; GO:0044877; GO:0060307; GO:0071805; GO:0086011; GO:0086091 32677 XM_044319003.1 81 170 44 41 45 Q9NRK6 0 ATP-binding cassette sub-family B member 10, mitochondrial (ABC-mitochondrial erythroid protein) (ABC-me protein) (ATP-binding cassette transporter 10) (ABC transporter 10 protein) (Mitochondrial ATP-binding cassette 2) (M-ABC2) Homo sapiens (Human) erythrocyte development [GO:0048821]; heme biosynthetic process [GO:0006783]; mitochondrial transport [GO:0006839]; mitochondrial unfolded protein response [GO:0034514]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of heme biosynthetic process [GO:0070455]; positive regulation of hemoglobin biosynthetic process [GO:0046985] GO:0005524; GO:0005739; GO:0005743; GO:0006783; GO:0006839; GO:0016887; GO:0031966; GO:0034514; GO:0042803; GO:0045648; GO:0046985; GO:0048821; GO:0070455; GO:0140359 32678 XM_029356664.2 11 59 0 5 0 NA NA NA NA NA NA 32679 XM_044307268.1 39 2 7 29 74 NA NA NA NA NA NA 32680 XM_029342787.2 121 240 24 182 176 P05363 3.61e-35 Substance-K receptor (SKR) (NK-2 receptor) (NK-2R) (Neurokinin A receptor) (Tachykinin receptor 2) Bos taurus (Bovine) positive regulation of flagellated sperm motility [GO:1902093]; regulation of uterine smooth muscle contraction [GO:0070472] GO:0004995; GO:0005886; GO:0016497; GO:0061827; GO:0070472; GO:0097225; GO:1902093 32681 XM_029358115.2 47 31 6 47 6 P56476 8.88e-57 Gamma-aminobutyric acid receptor subunit rho-2 (GABA(A) receptor subunit rho-2) (GABA(C) receptor) Mus musculus (Mouse) chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; chloride transport [GO:0006821]; gamma-aminobutyric acid signaling pathway [GO:0007214]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165]; visual perception [GO:0007601] GO:0004890; GO:0005231; GO:0005254; GO:0005886; GO:0006821; GO:0007165; GO:0007214; GO:0007268; GO:0007601; GO:0019904; GO:0030424; GO:0030594; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0098982; GO:1902476; GO:1902711; GO:1904315 32682 XM_029332142.2 310 215 120 227 205 NA NA NA NA NA NA 32683 XR_006395832.1 53 22 37 64 49 NA NA NA NA NA NA 32684 XM_029341122.2 3341 3003 2597 4295 3357 Q2HJE9 2.02e-39 Mitochondrial import inner membrane translocase subunit Tim17-B Bos taurus (Bovine) protein import into mitochondrial matrix [GO:0030150] GO:0005744; GO:0008320; GO:0030150 32685 XM_029355672.2 54 0 0 11 0 NA NA NA NA NA NA 32686 XM_044326879.1 36 0 39 0 0 A1KZ92 6.25e-25 Probable oxidoreductase PXDNL (EC 1.-.-.-) (Cardiac peroxidase) (Inactive peroxidasin-like protein) (Polysomal ribonuclease 1) (PRM1) (Vascular peroxidase 2) Homo sapiens (Human) hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979] GO:0004519; GO:0004601; GO:0005615; GO:0005783; GO:0005886; GO:0006979; GO:0020037; GO:0042744; GO:0046872; GO:0140825 32687 XM_029340186.2 1008 2123 602 824 688 P0C6T1 1.72e-25 Chromosome transmission fidelity protein 8 homolog Rattus norvegicus (Rat) DNA duplex unwinding [GO:0032508]; DNA replication [GO:0006260]; mitotic sister chromatid cohesion [GO:0007064]; positive regulation of DNA-directed DNA polymerase activity [GO:1900264] GO:0003677; GO:0006260; GO:0007064; GO:0031390; GO:0032508; GO:1900264 32688 XM_044316717.1 11 18 0 0 0 P02752 6.53e-36 Riboflavin-binding protein (RBP) [Cleaved into: Riboflavin-binding protein, plasma form; Riboflavin-binding protein, yolk major form; Riboflavin-binding protein, yolk minor form] Gallus gallus (Chicken) negative regulation of sensory perception of bitter taste [GO:1904661]; negative regulation of sensory perception of sweet taste [GO:1904657]; riboflavin transport [GO:0032218] GO:0009897; GO:0032217; GO:0032218; GO:0038023; GO:1902444; GO:1904657; GO:1904661 32689 XM_029344685.2 281 162 132 441 279 Q7Z020 1.58e-114 Transient receptor potential cation channel subfamily A member 1 (dTRPA1) (Ankyrin-like with transmembrane domains protein 1) (dANKTM1) Drosophila melanogaster (Fruit fly) calcium ion transport [GO:0006816]; cation transport [GO:0006812]; cellular response to heat [GO:0034605]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; detection of temperature stimulus involved in thermoception [GO:0050960]; mechanosensory behavior [GO:0007638]; negative phototaxis [GO:0046957]; neuronal signal transduction [GO:0023041]; phototransduction [GO:0007602]; positive regulation of calcium-mediated signaling [GO:0050850]; response to heat [GO:0009408]; response to light stimulus [GO:0009416]; temperature compensation of the circadian clock [GO:0010378]; thermosensory behavior [GO:0040040]; thermotaxis [GO:0043052] GO:0001580; GO:0005261; GO:0005262; GO:0005886; GO:0006812; GO:0006816; GO:0007602; GO:0007638; GO:0009408; GO:0009416; GO:0010378; GO:0015276; GO:0016020; GO:0023041; GO:0034605; GO:0034703; GO:0040040; GO:0043052; GO:0046957; GO:0050850; GO:0050960; GO:0050965; GO:0050968; GO:0097604 32690 XM_029356248.2 1041 787 457 568 673 Q1LWX3 6.07e-64 Protein N-terminal glutamine amidohydrolase (EC 3.5.1.122) (Protein NH2-terminal glutamine deamidase) (N-terminal Gln amidase) (Nt(Q)-amidase) (WDYHV motif-containing protein 1) Danio rerio (Zebrafish) (Brachydanio rerio) protein modification process [GO:0036211] GO:0005634; GO:0005829; GO:0008418; GO:0036211; GO:0070773 32691 XR_003823545.2 912 368 191 301 676 NA NA NA NA NA NA 32692 XM_044318305.1 1801 1557 624 1697 1387 P41515 0 DNA topoisomerase 2-alpha (EC 5.6.2.2) (DNA topoisomerase II, alpha isozyme) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) apoptotic chromosome condensation [GO:0030263]; cellular response to DNA damage stimulus [GO:0006974]; chromosome segregation [GO:0007059]; DNA ligation [GO:0006266]; DNA topological change [GO:0006265]; embryonic cleavage [GO:0040016]; female meiotic nuclear division [GO:0007143]; hematopoietic progenitor cell differentiation [GO:0002244]; negative regulation of DNA duplex unwinding [GO:1905463]; positive regulation of apoptotic process [GO:0043065]; positive regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045870]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511] GO:0000228; GO:0000287; GO:0000775; GO:0000793; GO:0001673; GO:0002244; GO:0003682; GO:0003918; GO:0005080; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005814; GO:0006265; GO:0006266; GO:0006974; GO:0007059; GO:0007143; GO:0008022; GO:0008301; GO:0009330; GO:0030263; GO:0040016; GO:0042752; GO:0042803; GO:0042826; GO:0043065; GO:0043130; GO:0045870; GO:0045944; GO:0046982; GO:0048511; GO:1905463; GO:1990904 32693 XM_044327496.1 1576 2024 321 2696 2871 NA NA NA NA NA NA 32694 XM_029349829.2 252 257 152 285 131 Q8NBL1 5.75e-168 Protein O-glucosyltransferase 1 (EC 2.4.1.376) (CAP10-like 46 kDa protein) (hCLP46) (KTEL motif-containing protein 1) (Myelodysplastic syndromes relative protein) (O-glucosyltransferase Rumi homolog) (hRumi) (Protein O-xylosyltransferase POGLUT1) (EC 2.4.2.63) Homo sapiens (Human) axial mesoderm development [GO:0048318]; circulatory system development [GO:0072359]; gastrulation [GO:0007369]; muscle tissue development [GO:0060537]; paraxial mesoderm development [GO:0048339]; positive regulation of Notch signaling pathway [GO:0045747]; protein O-linked glycosylation [GO:0006493]; protein O-linked glycosylation via serine [GO:0018242]; regulation of gastrulation [GO:0010470]; somitogenesis [GO:0001756] GO:0001756; GO:0005783; GO:0005788; GO:0006493; GO:0007369; GO:0010470; GO:0012505; GO:0018242; GO:0035251; GO:0035252; GO:0045747; GO:0046527; GO:0048318; GO:0048339; GO:0060537; GO:0072359; GO:0140561; GO:0140562 32695 XM_044319846.1 2589 2265 959 2498 1271 Q11136 0 Xaa-Pro dipeptidase (X-Pro dipeptidase) (EC 3.4.13.9) (Imidodipeptidase) (Peptidase 4) (Peptidase D) (Proline dipeptidase) (Prolidase) Mus musculus (Mouse) collagen catabolic process [GO:0030574]; proteolysis [GO:0006508] GO:0006508; GO:0008233; GO:0030145; GO:0030574; GO:0070006; GO:0102009 32696 XM_044318844.1 79 7 66 35 82 NA NA NA NA NA NA 32697 XM_029328387.2 11 12 15 20 21 NA NA NA NA NA NA 32698 XM_029348769.2 588 610 382 512 620 Q66JE4 1.26e-54 E3 ubiquitin-protein ligase rnf146 (EC 2.3.2.27) (RING finger protein 146) (RING-type E3 ubiquitin transferase rnf146) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) positive regulation of canonical Wnt signaling pathway [GO:0090263]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt signaling pathway [GO:0016055] GO:0004842; GO:0005634; GO:0005829; GO:0006511; GO:0008270; GO:0016055; GO:0051865; GO:0061630; GO:0070936; GO:0072572; GO:0090263 32699 XM_029340877.2 126 74 28 92 92 O93430 2.5e-69 Glycine receptor subunit alphaZ1 Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to amino acid stimulus [GO:0071230]; cellular response to ethanol [GO:0071361]; cellular response to zinc ion [GO:0071294]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; nervous system process [GO:0050877]; neuropeptide signaling pathway [GO:0007218]; regulation of membrane potential [GO:0042391]; regulation of neuron differentiation [GO:0045664]; response to amino acid [GO:0043200]; signal transduction [GO:0007165]; synaptic transmission, glycinergic [GO:0060012] GO:0004888; GO:0005231; GO:0005886; GO:0006811; GO:0007165; GO:0007218; GO:0007268; GO:0007417; GO:0008270; GO:0016594; GO:0016933; GO:0016934; GO:0030425; GO:0030594; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0043200; GO:0043204; GO:0045202; GO:0045211; GO:0045664; GO:0050877; GO:0060012; GO:0071230; GO:0071294; GO:0071361; GO:1902476; GO:1904315 32700 XM_044308407.1 447 210 249 331 247 NA NA NA NA NA NA 32701 XM_029334232.2 0 17 0 17 0 Q9HBY0 1.06e-174 NADPH oxidase 3 (EC 1.6.3.-) (Mitogenic oxidase 2) (MOX-2) (gp91phox homolog 3) (GP91-3) Homo sapiens (Human) defense response [GO:0006952]; detection of gravity [GO:0009590]; otolith development [GO:0048840]; superoxide anion generation [GO:0042554]; temperature homeostasis [GO:0001659] GO:0001659; GO:0005737; GO:0005886; GO:0006952; GO:0009590; GO:0016175; GO:0042554; GO:0043020; GO:0048840; GO:0070062 32702 XR_003826270.2 5789 6975 4158 7270 3188 NA NA NA NA NA NA 32703 XR_006398148.1 26 12 10 13 5 E9Q236 0 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 32704 XR_006398148.1 26 12 10 13 5 E9Q236 0 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 32705 XM_044325741.1 0 3 0 0 10 NA NA NA NA NA NA 32706 XM_029341480.2 10029 8574 4230 6620 6367 P63245 0 Receptor of activated protein C kinase 1 (Guanine nucleotide-binding protein subunit beta-2-like 1) (Receptor for activated C kinase) (Receptor of activated protein kinase C 1) [Cleaved into: Receptor of activated protein C kinase 1, N-terminally processed] Rattus norvegicus (Rat) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cell cycle [GO:0007049]; cellular response to glucose stimulus [GO:0071333]; cellular response to growth factor stimulus [GO:0071363]; gastrulation [GO:0007369]; negative regulation of cell growth [GO:0030308]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of phagocytosis [GO:0050765]; negative regulation of protein binding [GO:0032091]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of translation [GO:0017148]; negative regulation of Wnt signaling pathway [GO:0030178]; osteoblast differentiation [GO:0001649]; pigmentation [GO:0043473]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration [GO:0030335]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of gastrulation [GO:2000543]; positive regulation of Golgi to plasma membrane protein transport [GO:0042998]; positive regulation of GTPase activity [GO:0043547]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein-containing complex assembly [GO:0031334]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; protein ubiquitination [GO:0016567]; regulation of cell cycle [GO:0051726]; regulation of cell division [GO:0051302]; regulation of establishment of cell polarity [GO:2000114]; regulation of protein localization [GO:0032880]; regulation of protein localization to plasma membrane [GO:1903076]; rescue of stalled ribosome [GO:0072344]; rhythmic process [GO:0048511]; translation [GO:0006412] GO:0001649; GO:0001891; GO:0001934; GO:0005080; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0006412; GO:0006919; GO:0007049; GO:0007205; GO:0007369; GO:0008200; GO:0008656; GO:0010629; GO:0015935; GO:0016020; GO:0016567; GO:0017148; GO:0019899; GO:0019903; GO:0030178; GO:0030292; GO:0030308; GO:0030332; GO:0030335; GO:0030425; GO:0030496; GO:0030971; GO:0031334; GO:0032091; GO:0032436; GO:0032880; GO:0033137; GO:0035591; GO:0042169; GO:0042803; GO:0042998; GO:0043005; GO:0043022; GO:0043025; GO:0043065; GO:0043204; GO:0043473; GO:0043547; GO:0044297; GO:0045182; GO:0045879; GO:0048471; GO:0048511; GO:0050765; GO:0051302; GO:0051343; GO:0051434; GO:0051726; GO:0051898; GO:0051901; GO:0071333; GO:0071363; GO:0072344; GO:1903076; GO:1903208; GO:1990630; GO:2000114; GO:2000543; GO:2001244 32707 XM_044323125.1 4 21 0 13 0 NA NA NA NA NA NA 32708 XM_044321148.1 219 108 172 48 1092 Q9NYT0 2.8e-46 Pleckstrin-2 Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; intracellular signal transduction [GO:0035556]; positive regulation of plasma membrane bounded cell projection assembly [GO:0120034] GO:0005737; GO:0005856; GO:0005886; GO:0031258; GO:0031532; GO:0032266; GO:0035556; GO:0043325; GO:0080025; GO:0120034 32709 XM_044309976.1 72 120 63 109 174 Q15485 8.89e-80 Ficolin-2 (37 kDa elastin-binding protein) (Collagen/fibrinogen domain-containing protein 2) (EBP-37) (Ficolin-B) (Ficolin-beta) (Hucolin) (L-ficolin) (Serum lectin p35) Homo sapiens (Human) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; positive regulation of opsonization [GO:1903028]; proteolysis [GO:0006508]; recognition of apoptotic cell [GO:0043654] GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005576; GO:0005581; GO:0005615; GO:0006508; GO:0008228; GO:0009897; GO:0042802; GO:0043394; GO:0043654; GO:0046872; GO:0048306; GO:0050829; GO:0050830; GO:0062023; GO:0070062; GO:0072562; GO:0097367; GO:1903028; GO:1905370; GO:2001065 32710 XM_044310467.1 484 382 263 421 401 Q7S8Z0 6.01e-85 Cytosolic Fe-S cluster assembly factor nbp35 (Nucleotide-binding protein 35) Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) iron-sulfur cluster assembly [GO:0016226] GO:0005524; GO:0005829; GO:0016226; GO:0046872; GO:0051536; GO:0051539; GO:0140663 32711 XM_029358116.2 2829 2593 1847 2859 2482 Q9JJ31 0 Cullin-5 (CUL-5) (Vasopressin-activated calcium-mobilizing receptor 1) (VACM-1) Rattus norvegicus (Rat) cerebral cortex radially oriented cell migration [GO:0021799]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; radial glia guided migration of Purkinje cell [GO:0021942]; regulation of cytosolic calcium ion concentration [GO:0051480]; response to osmotic stress [GO:0006970]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0000209; GO:0004842; GO:0005000; GO:0005634; GO:0005737; GO:0005886; GO:0006970; GO:0016567; GO:0019005; GO:0021799; GO:0021942; GO:0030674; GO:0031146; GO:0031461; GO:0031466; GO:0031625; GO:0051480; GO:0090734 32712 XM_029351593.2 782 559 420 536 427 Q4KLZ6 6.43e-146 Triokinase/FMN cyclase (Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing)) [Includes: ATP-dependent dihydroxyacetone kinase (DHA kinase) (EC 2.7.1.28) (EC 2.7.1.29) (Glycerone kinase) (Triokinase) (Triose kinase); FAD-AMP lyase (cyclizing) (EC 4.6.1.15) (FAD-AMP lyase (cyclic FMN forming)) (FMN cyclase)] Rattus norvegicus (Rat) carbohydrate phosphorylation [GO:0046835]; cellular carbohydrate metabolic process [GO:0044262]; fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; glycerol catabolic process [GO:0019563]; negative regulation of MDA-5 signaling pathway [GO:0039534]; regulation of innate immune response [GO:0045088] GO:0004371; GO:0005524; GO:0005829; GO:0019563; GO:0034012; GO:0039534; GO:0044262; GO:0045088; GO:0046835; GO:0046872; GO:0050354; GO:0061624 32713 XM_044316119.1 2 1 8 3 18 NA NA NA NA NA NA 32714 XM_029351333.2 184 151 174 124 124 NA NA NA NA NA NA 32715 XM_044324976.1 23 1 0 20 18 Q96AY4 5.89e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32716 XM_044324976.1 23 1 0 20 18 Q96AY4 2.09e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32717 XM_044324976.1 23 1 0 20 18 Q96AY4 2.26e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32718 XM_044324976.1 23 1 0 20 18 Q96AY4 8.28e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32719 XM_044324976.1 23 1 0 20 18 Q96AY4 9.2e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32720 XM_044324976.1 23 1 0 20 18 Q96AY4 9.37e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32721 XM_044324976.1 23 1 0 20 18 Q96AY4 6.42e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32722 XM_044324976.1 23 1 0 20 18 Q96AY4 8.81e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32723 XM_044324976.1 23 1 0 20 18 Q96AY4 5.27e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32724 XM_044324976.1 23 1 0 20 18 Q96AY4 1.92e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32725 XM_044324976.1 23 1 0 20 18 Q96AY4 5.86e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32726 XM_044319175.1 16 0 18 0 0 NA NA NA NA NA NA 32727 XM_029329823.2 15114 18393 10824 15286 9638 NA NA NA NA NA NA 32728 XM_044328889.1 2713 3418 2959 2145 3648 P05307 3.31e-50 Protein disulfide-isomerase (PDI) (EC 5.3.4.1) (Cellular thyroid hormone-binding protein) (Prolyl 4-hydroxylase subunit beta) (p55) Bos taurus (Bovine) peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976] GO:0003756; GO:0004656; GO:0005783; GO:0005788; GO:0006457; GO:0009897; GO:0018401; GO:0034976; GO:0042470; GO:0046982 32729 XR_003824601.2 3 8 7 21 10 NA NA NA NA NA NA 32730 XM_029334096.2 321 175 203 317 367 P48547 3.99e-119 Potassium voltage-gated channel subfamily C member 1 (NGK2) (Voltage-gated potassium channel subunit Kv3.1) (Voltage-gated potassium channel subunit Kv4) Homo sapiens (Human) cellular response to xenobiotic stimulus [GO:0071466]; cerebellum development [GO:0021549]; corpus callosum development [GO:0022038]; globus pallidus development [GO:0021759]; optic nerve development [GO:0021554]; positive regulation of voltage-gated potassium channel activity [GO:1903818]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; protein tetramerization [GO:0051262]; response to amine [GO:0014075]; response to auditory stimulus [GO:0010996]; response to fibroblast growth factor [GO:0071774]; response to light intensity [GO:0009642]; response to nerve growth factor [GO:1990089]; response to potassium ion [GO:0035864]; response to toxic substance [GO:0009636] GO:0005249; GO:0005251; GO:0005886; GO:0006813; GO:0008076; GO:0009636; GO:0009642; GO:0009986; GO:0010996; GO:0014075; GO:0016020; GO:0019894; GO:0021549; GO:0021554; GO:0021759; GO:0022038; GO:0030424; GO:0030673; GO:0032590; GO:0032809; GO:0035864; GO:0042734; GO:0044305; GO:0044325; GO:0045211; GO:0051260; GO:0051262; GO:0071466; GO:0071774; GO:0071805; GO:0099508; GO:1903818; GO:1990089 32731 XR_006393179.1 35 30 24 132 154 NA NA NA NA NA NA 32732 XM_044328831.1 16 0 18 1 0 NA NA NA NA NA NA 32733 XM_029324610.2 471 154 211 254 171 Q6N075 1.02e-121 Molybdate-anion transporter (Major facilitator superfamily domain-containing protein 5) (Molybdate transporter 2 homolog) (hsMOT2) Homo sapiens (Human) NA GO:0005886; GO:0015098; GO:0016020 32734 XM_029328889.2 1502 1444 990 835 4198 Q8BLA8 4.25e-121 Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Wasabi receptor) Mus musculus (Mouse) calcium ion transmembrane import into cytosol [GO:0097553]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cell surface receptor signaling pathway [GO:0007166]; cellular calcium ion homeostasis [GO:0006874]; cellular response to carbon dioxide [GO:0071244]; cellular response to cold [GO:0070417]; cellular response to heat [GO:0034605]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to organic substance [GO:0071310]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; positive regulation of anion transport [GO:1903793]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of sensory perception of pain [GO:1904058]; protein homotetramerization [GO:0051289]; regulation of blood circulation [GO:1903522]; regulation of neuronal action potential [GO:0098908]; response to cold [GO:0009409]; response to hydrogen peroxide [GO:0042542]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; sensory perception of pain [GO:0019233]; thermoception [GO:0050955]; urinary bladder smooth muscle contraction [GO:0014832] GO:0005216; GO:0005245; GO:0005262; GO:0005886; GO:0006816; GO:0006874; GO:0007166; GO:0009409; GO:0009410; GO:0010033; GO:0014070; GO:0014832; GO:0015267; GO:0015278; GO:0016020; GO:0016324; GO:0019233; GO:0030424; GO:0032421; GO:0034605; GO:0035774; GO:0042542; GO:0042802; GO:0048265; GO:0050955; GO:0050966; GO:0050968; GO:0050974; GO:0051289; GO:0070301; GO:0070417; GO:0070588; GO:0071244; GO:0071310; GO:0097553; GO:0097604; GO:0098908; GO:1903522; GO:1903793; GO:1904058; GO:1990760 32735 XR_006395978.1 78 66 73 86 63 P30825 2.27e-150 High affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (Ecotropic retroviral leukemia receptor homolog) (Ecotropic retrovirus receptor homolog) (Solute carrier family 7 member 1) (System Y+ basic amino acid transporter) Homo sapiens (Human) amino acid import across plasma membrane [GO:0089718]; amino acid transport [GO:0006865]; L-amino acid transport [GO:0015807]; L-arginine import across plasma membrane [GO:0097638]; L-arginine transmembrane transport [GO:1903826]; L-histidine import across plasma membrane [GO:1903810]; L-ornithine transmembrane transport [GO:1903352]; lysine transport [GO:0015819]; ornithine transport [GO:0015822]; positive regulation of T cell proliferation [GO:0042102]; transport across blood-brain barrier [GO:0150104] GO:0000064; GO:0001618; GO:0005290; GO:0005886; GO:0006865; GO:0009925; GO:0015171; GO:0015174; GO:0015189; GO:0015807; GO:0015819; GO:0015822; GO:0016020; GO:0016323; GO:0016324; GO:0032991; GO:0042102; GO:0061459; GO:0089718; GO:0097638; GO:0150104; GO:1903352; GO:1903810; GO:1903826 32736 XM_044329309.1 2184 3690 1450 2117 1149 NA NA NA NA NA NA 32737 XM_029342703.2 1387 1237 1379 1613 2005 Q9PUB8 7.99e-88 Zinc transporter Slc39a7 (Histidine-rich membrane protein Ke4) (Solute carrier family 39 member 7) (Zrt-, Irt-like protein 7) (ZIP7) Danio rerio (Zebrafish) (Brachydanio rerio) cellular zinc ion homeostasis [GO:0006882]; zinc ion homeostasis [GO:0055069]; zinc ion transmembrane transport [GO:0071577]; zinc ion transport [GO:0006829] GO:0005385; GO:0005789; GO:0005794; GO:0006829; GO:0006882; GO:0055069; GO:0071577 32738 XM_044321478.1 38 26 30 23 21 NA NA NA NA NA NA 32739 XM_029334661.2 1566 744 726 1383 1775 NA NA NA NA NA NA 32740 XM_029349889.2 17 20 9 15 56 A0A2B4RNI3 0 NA NA NA NA 32741 XM_044327746.1 369 307 217 258 237 Q7RTR2 1.88e-35 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 32742 XM_044327746.1 369 307 217 258 237 Q7RTR2 7.11e-31 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 32743 XM_044327746.1 369 307 217 258 237 Q7RTR2 1.41e-24 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 32744 XM_029343042.2 675 318 311 649 599 NA NA NA NA NA NA 32745 XM_029355990.2 0 0 10 0 0 NA NA NA NA NA NA 32746 XM_044306983.1 1794 805 1362 2974 1118 Q6V0I7 1.43e-58 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 32747 XM_044306983.1 1794 805 1362 2974 1118 Q6V0I7 1.55e-55 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 32748 XM_044306983.1 1794 805 1362 2974 1118 Q6V0I7 3.99e-43 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 32749 XM_044306983.1 1794 805 1362 2974 1118 Q6V0I7 1.25e-40 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 32750 XM_044306983.1 1794 805 1362 2974 1118 Q6V0I7 4.7e-40 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 32751 XM_044306983.1 1794 805 1362 2974 1118 Q6V0I7 2.52e-39 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 32752 XM_044306983.1 1794 805 1362 2974 1118 Q6V0I7 3.16e-35 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 32753 XM_044306983.1 1794 805 1362 2974 1118 Q6V0I7 6.64e-29 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 32754 XM_044306983.1 1794 805 1362 2974 1118 Q6V0I7 1.86e-26 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 32755 XM_044306983.1 1794 805 1362 2974 1118 Q6V0I7 5.17e-26 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 32756 XM_044306983.1 1794 805 1362 2974 1118 Q6V0I7 2.46e-23 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 32757 XM_029349837.2 2635 2540 1757 2421 2469 P25207 6e-57 Nuclear transcription factor Y subunit beta (CAAT box DNA-binding protein subunit B) (Nuclear transcription factor Y subunit B) (NF-YB) Gallus gallus (Chicken) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000981; GO:0001228; GO:0006357; GO:0016602; GO:0043565; GO:0046982 32758 XM_029343707.2 0 9 114 224 0 NA NA NA NA NA NA 32759 XM_029334542.2 5 0 8 1 1 Q8TE60 2.97e-101 A disintegrin and metalloproteinase with thrombospondin motifs 18 (ADAM-TS 18) (ADAM-TS18) (ADAMTS-18) (EC 3.4.24.-) Homo sapiens (Human) extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; negative regulation of platelet aggregation [GO:0090331]; proteolysis [GO:0006508] GO:0001654; GO:0004222; GO:0005576; GO:0006508; GO:0030198; GO:0031012; GO:0046872; GO:0090331 32760 XM_044319357.1 1863 774 750 833 1361 NA NA NA NA NA NA 32761 XM_029333480.2 0 2 1 8 15 NA NA NA NA NA NA 32762 XM_029328756.2 969 516 380 952 967 Q6PCX9 0 E3 ubiquitin-protein ligase TRIM37 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TRIM37) (Tripartite motif-containing protein 37) Mus musculus (Mouse) aggresome assembly [GO:0070842]; histone H2A monoubiquitination [GO:0035518]; histone H2A-K119 monoubiquitination [GO:0036353]; negative regulation of centriole replication [GO:0046600]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein autoubiquitination [GO:0051865]; protein import into peroxisome matrix [GO:0016558] GO:0000122; GO:0003682; GO:0003713; GO:0004842; GO:0005164; GO:0005694; GO:0005737; GO:0005777; GO:0005778; GO:0005829; GO:0008270; GO:0016235; GO:0016558; GO:0031625; GO:0032088; GO:0035098; GO:0035518; GO:0036353; GO:0042803; GO:0046600; GO:0048471; GO:0051091; GO:0051092; GO:0051865; GO:0061630; GO:0070842 32763 XM_044310588.1 33 0 15 3 51 NA NA NA NA NA NA 32764 XM_029357121.2 162 46 95 84 114 A7RJI7 0 Vacuolar fusion protein CCZ1 homolog Nematostella vectensis (Starlet sea anemone) vesicle-mediated transport [GO:0016192] GO:0016192; GO:0035658; GO:0043231 32765 XM_029344159.2 26 15 9 12 14 NA NA NA NA NA NA 32766 XR_003824240.2 60 6 7 40 64 NA NA NA NA NA NA 32767 XM_044308520.1 118 63 44 48 248 A1DPK7 4.12e-73 Actin-related protein 2/3 complex subunit 3-A Xenopus laevis (African clawed frog) Arp2/3 complex-mediated actin nucleation [GO:0034314]; regulation of actin filament polymerization [GO:0030833] GO:0003779; GO:0005634; GO:0005737; GO:0005885; GO:0030833; GO:0034314; GO:0035861; GO:0042995 32768 XM_029340700.2 4761 7935 5083 9183 7854 Q5ZK14 2.14e-26 DET1- and DDB1-associated protein 1 Gallus gallus (Chicken) positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209] GO:0000209; GO:0032436; GO:0080008 32769 XM_044313154.1 63 39 22 50 95 NA NA NA NA NA NA 32770 XM_044326002.1 51 50 34 85 31 Q5M954 7.98e-61 tRNA-splicing endonuclease subunit Sen2 (EC 4.6.1.16) (tRNA-intron endonuclease Sen2) Rattus norvegicus (Rat) mRNA processing [GO:0006397]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]; tRNA-type intron splice site recognition and cleavage [GO:0000379] GO:0000213; GO:0000214; GO:0000379; GO:0003676; GO:0005654; GO:0005730; GO:0005813; GO:0005829; GO:0006388; GO:0006397; GO:0016829 32771 XM_029323547.2 0 0 15 0 75 P0C6B8 0 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 32772 XM_029323547.2 0 0 15 0 75 P0C6B8 4.65e-57 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 32773 XM_029323547.2 0 0 15 0 75 P0C6B8 3.43e-52 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 32774 XM_029323547.2 0 0 15 0 75 P0C6B8 2.29e-49 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 32775 XM_029323547.2 0 0 15 0 75 P0C6B8 7.48e-49 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 32776 XM_029323547.2 0 0 15 0 75 P0C6B8 1.52e-45 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 32777 XM_029323547.2 0 0 15 0 75 P0C6B8 1.9e-42 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 32778 XM_029323547.2 0 0 15 0 75 P0C6B8 3.07e-42 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 32779 XM_029323547.2 0 0 15 0 75 P0C6B8 2.08e-41 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 32780 XM_029323547.2 0 0 15 0 75 P0C6B8 2.01e-40 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 32781 XM_029323547.2 0 0 15 0 75 P0C6B8 1.83e-39 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 32782 XM_029323547.2 0 0 15 0 75 P0C6B8 7.28e-37 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 32783 XM_029323547.2 0 0 15 0 75 P0C6B8 2.58e-29 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 32784 XM_029323547.2 0 0 15 0 75 P0C6B8 5.22e-26 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 32785 XM_029326850.2 195 527 182 1788 243 Q2M3R5 4.08e-45 Solute carrier family 35 member G1 (Partner of STIM1) (Transmembrane protein 20) Homo sapiens (Human) calcium ion export across plasma membrane [GO:1990034]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0005789; GO:0005886; GO:0016020; GO:0051480; GO:1990034 32786 XM_029329526.2 2500 1497 1127 2029 824 G5EG78 9.16e-81 Peroxidasin homolog pxn-2 (EC 1.11.2.-) Caenorhabditis elegans axon guidance [GO:0007411]; basement membrane organization [GO:0071711]; embryonic body morphogenesis [GO:0010172]; muscle attachment [GO:0016203]; negative regulation of axon regeneration [GO:0048681]; regulation of basement membrane organization [GO:0110011]; response to oxidative stress [GO:0006979] GO:0004601; GO:0005604; GO:0005615; GO:0006979; GO:0007411; GO:0010172; GO:0016203; GO:0020037; GO:0046872; GO:0048681; GO:0071711; GO:0110011; GO:0140825 32787 XR_006392356.1 2 51 15 26 0 NA NA NA NA NA NA 32788 XM_029356385.2 94 38 148 147 152 NA NA NA NA NA NA 32789 XM_044326924.1 0 0 246 53 20 NA NA NA NA NA NA 32790 XM_029334411.2 149 130 116 7 257 NA NA NA NA NA NA 32791 XR_003827852.2 62 155 88 396 247 Q9M2U3 2.06e-24 Protein ALP1-like (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) NA GO:0000118; GO:0004518; GO:0046872 32792 XM_029357975.2 1020 625 395 591 564 P61963 0 DDB1- and CUL4-associated factor 7 (WD repeat-containing protein 68) (WD repeat-containing protein An11 homolog) Mus musculus (Mouse) protein ubiquitination [GO:0016567] GO:0005634; GO:0005654; GO:0005829; GO:0016363; GO:0016567; GO:0016604; GO:0032991; GO:0080008 32793 XM_029331169.2 234 125 135 190 258 C9JQI7 4.07e-29 Transmembrane protein 232 Homo sapiens (Human) NA GO:0016020 32794 XM_044307193.1 757 656 356 470 366 NA NA NA NA NA NA 32795 XM_044312773.1 455 299 303 276 382 Q8K4Q6 9.18e-95 Endonuclease 8-like 1 (EC 3.2.2.-) (EC 4.2.99.18) (DNA glycosylase/AP lyase Neil1) (DNA-(apurinic or apyrimidinic site) lyase Neil1) (Endonuclease VIII-like 1) (Nei homolog 1) (NEH1) (Nei-like protein 1) Mus musculus (Mouse) base-excision repair [GO:0006284]; DNA repair [GO:0006281]; negative regulation of nuclease activity [GO:0032074]; response to oxidative stress [GO:0006979] GO:0003684; GO:0003906; GO:0005634; GO:0005654; GO:0005694; GO:0005737; GO:0005815; GO:0006281; GO:0006284; GO:0006979; GO:0008022; GO:0008270; GO:0016798; GO:0016829; GO:0019104; GO:0032074; GO:0140078 32796 XM_029331715.2 0 0 0 9 0 Q5T1B0 4.54e-143 Axonemal dynein light chain domain-containing protein 1 Homo sapiens (Human) NA NA 32797 XM_044326227.1 0 0 6 0 6 Q9M2U3 5.7e-35 Protein ALP1-like (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) NA GO:0000118; GO:0004518; GO:0046872 32798 XM_044325999.1 387 202 185 317 321 Q8VE97 2.62e-37 Serine/arginine-rich splicing factor 4 (Splicing factor, arginine/serine-rich 4) Mus musculus (Mouse) hematopoietic progenitor cell differentiation [GO:0002244]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025] GO:0000398; GO:0002244; GO:0003723; GO:0003729; GO:0005634; GO:0016607; GO:0048025; GO:1990825 32799 XM_044325643.1 1092 855 1398 1944 1043 NA NA NA NA NA NA 32800 XM_029356830.2 2 6 0 0 10 NA NA NA NA NA NA 32801 XM_029355610.2 0 0 23 453 90 NA NA NA NA NA NA 32802 XM_029357463.2 102 89 171 193 0 NA NA NA NA NA NA 32803 XM_029337237.2 17066 24336 9974 14099 11899 P62246 1.1e-78 40S ribosomal protein S15a Rattus norvegicus (Rat) positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; response to virus [GO:0009615]; translation [GO:0006412] GO:0003735; GO:0005737; GO:0006412; GO:0008284; GO:0009615; GO:0022626; GO:0022627; GO:0045202; GO:0045787 32804 XM_044317567.1 0 5 1 10 3 NA NA NA NA NA NA 32805 XM_044324506.1 53 3 44 13 243 NA NA NA NA NA NA 32806 XM_044307821.1 0 0 32 0 11 NA NA NA NA NA NA 32807 XM_029348539.2 1891 1507 888 2086 1486 Q99KY4 0 Cyclin-G-associated kinase (EC 2.7.11.1) Mus musculus (Mouse) cell cycle [GO:0007049]; clathrin coat disassembly [GO:0072318]; clathrin-coated pit assembly [GO:1905224]; clathrin-dependent endocytosis [GO:0072583]; endoplasmic reticulum organization [GO:0007029]; epidermal cell differentiation [GO:0009913]; epithelial cell development [GO:0002064]; establishment of skin barrier [GO:0061436]; forebrain morphogenesis [GO:0048853]; Golgi organization [GO:0007030]; Golgi to lysosome transport [GO:0090160]; intrahepatic bile duct development [GO:0035622]; keratinocyte differentiation [GO:0030216]; negative regulation of neuron projection development [GO:0010977]; neural precursor cell proliferation [GO:0061351]; neuroepithelial cell differentiation [GO:0060563]; positive regulation of neural precursor cell proliferation [GO:2000179]; protein localization to Golgi apparatus [GO:0034067]; protein localization to plasma membrane [GO:0072659]; protein phosphorylation [GO:0006468]; receptor-mediated endocytosis [GO:0006898]; stem cell differentiation [GO:0048863] GO:0002064; GO:0004674; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005925; GO:0006468; GO:0006898; GO:0007029; GO:0007030; GO:0007049; GO:0009913; GO:0010977; GO:0030216; GO:0030276; GO:0030332; GO:0031982; GO:0034067; GO:0035622; GO:0043231; GO:0048471; GO:0048853; GO:0048863; GO:0060563; GO:0061351; GO:0061436; GO:0072318; GO:0072583; GO:0072659; GO:0090160; GO:0106310; GO:1905224; GO:2000179 32808 XM_029348539.2 1891 1507 888 2086 1486 Q99KY4 2.06e-39 Cyclin-G-associated kinase (EC 2.7.11.1) Mus musculus (Mouse) cell cycle [GO:0007049]; clathrin coat disassembly [GO:0072318]; clathrin-coated pit assembly [GO:1905224]; clathrin-dependent endocytosis [GO:0072583]; endoplasmic reticulum organization [GO:0007029]; epidermal cell differentiation [GO:0009913]; epithelial cell development [GO:0002064]; establishment of skin barrier [GO:0061436]; forebrain morphogenesis [GO:0048853]; Golgi organization [GO:0007030]; Golgi to lysosome transport [GO:0090160]; intrahepatic bile duct development [GO:0035622]; keratinocyte differentiation [GO:0030216]; negative regulation of neuron projection development [GO:0010977]; neural precursor cell proliferation [GO:0061351]; neuroepithelial cell differentiation [GO:0060563]; positive regulation of neural precursor cell proliferation [GO:2000179]; protein localization to Golgi apparatus [GO:0034067]; protein localization to plasma membrane [GO:0072659]; protein phosphorylation [GO:0006468]; receptor-mediated endocytosis [GO:0006898]; stem cell differentiation [GO:0048863] GO:0002064; GO:0004674; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005925; GO:0006468; GO:0006898; GO:0007029; GO:0007030; GO:0007049; GO:0009913; GO:0010977; GO:0030216; GO:0030276; GO:0030332; GO:0031982; GO:0034067; GO:0035622; GO:0043231; GO:0048471; GO:0048853; GO:0048863; GO:0060563; GO:0061351; GO:0061436; GO:0072318; GO:0072583; GO:0072659; GO:0090160; GO:0106310; GO:1905224; GO:2000179 32809 XR_006395311.1 29 6 0 3 0 NA NA NA NA NA NA 32810 XM_044327283.1 4 4 0 14 22 NA NA NA NA NA NA 32811 XM_044327645.1 18594 13683 10797 20624 18139 Q01082 0 Spectrin beta chain, non-erythrocytic 1 (Beta-II spectrin) (Fodrin beta chain) (Spectrin, non-erythroid beta chain 1) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; actin filament capping [GO:0051693]; central nervous system development [GO:0007417]; central nervous system formation [GO:0021556]; common-partner SMAD protein phosphorylation [GO:0007182]; Golgi to plasma membrane protein transport [GO:0043001]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; plasma membrane organization [GO:0007009]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein localization to plasma membrane [GO:0072659]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of SMAD protein signal transduction [GO:0060390] GO:0000281; GO:0003723; GO:0003779; GO:0005200; GO:0005516; GO:0005543; GO:0005730; GO:0005737; GO:0005829; GO:0005886; GO:0007009; GO:0007182; GO:0007417; GO:0008091; GO:0014069; GO:0014731; GO:0021556; GO:0030036; GO:0030054; GO:0030506; GO:0030673; GO:0030864; GO:0031430; GO:0032437; GO:0032743; GO:0042995; GO:0043001; GO:0045296; GO:0051015; GO:0051020; GO:0051693; GO:0060390; GO:0070062; GO:0071709; GO:0072659; GO:0098978; GO:1903076; GO:1903078 32812 XM_044319072.1 1020 609 410 794 271 Q5RET6 2.53e-152 Transmembrane protein 184C (Transmembrane protein 34) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0016020 32813 XM_044316720.1 16 0 115 14 5 P14207 1.02e-35 Folate receptor beta (FR-beta) (Folate receptor 2) (Folate receptor, fetal/placental) (Placental folate-binding protein) (FBP) Homo sapiens (Human) cell adhesion [GO:0007155]; folic acid transport [GO:0015884]; fusion of sperm to egg plasma membrane involved in single fertilization [GO:0007342]; inflammatory response [GO:0006954]; positive regulation of cell population proliferation [GO:0008284]; sperm-egg recognition [GO:0035036] GO:0005542; GO:0005576; GO:0005886; GO:0006954; GO:0007155; GO:0007342; GO:0008284; GO:0009897; GO:0009986; GO:0015884; GO:0035036; GO:0038023; GO:0061714 32814 XM_044328946.1 6 0 0 0 13 NA NA NA NA NA NA 32815 XM_029335027.2 632 256 215 536 531 Q3TC93 3.68e-22 HCLS1-binding protein 3 (HS1-binding protein 3) (HSP1BP-3) Mus musculus (Mouse) cell surface receptor signaling pathway [GO:0007166]; regulation of apoptotic process [GO:0042981]; T cell differentiation [GO:0030217] GO:0005739; GO:0005783; GO:0007166; GO:0030217; GO:0035091; GO:0042981 32816 XM_029332259.2 33 0 0 0 0 Q9HCD5 2.37e-32 Nuclear receptor coactivator 5 (NCoA-5) (Coactivator independent of AF-2) (CIA) Homo sapiens (Human) glucose homeostasis [GO:0042593]; insulin receptor signaling pathway [GO:0008286]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of signal transduction [GO:0009966] GO:0000122; GO:0003682; GO:0003714; GO:0003723; GO:0005615; GO:0005654; GO:0008286; GO:0009966; GO:0015629; GO:0042593; GO:0046627 32817 XM_044328017.1 10 7 10 5 70 NA NA NA NA NA NA 32818 XM_029328921.2 336 210 135 312 232 Q6YC49 9.7e-126 UDP-N-acetylglucosamine transporter (Golgi UDP-GlcNAc transporter) (Solute carrier family 35 member A3) Bos taurus (Bovine) carbohydrate transport [GO:0008643]; UDP-N-acetylglucosamine transmembrane transport [GO:1990569] GO:0000139; GO:0005459; GO:0008643; GO:1990569 32819 XR_006392513.1 34 1 5 0 5 NA NA NA NA NA NA 32820 XM_029324715.2 470 237 174 321 381 P48630 1.84e-115 Omega-6 fatty acid desaturase, endoplasmic reticulum isozyme 1 (EC 1.14.19.-) Glycine max (Soybean) (Glycine hispida) unsaturated fatty acid biosynthetic process [GO:0006636] GO:0005789; GO:0006636; GO:0016491 32821 XM_029324478.2 509 331 286 293 399 Q8TBR7 3.44e-32 TLC domain-containing protein 3A (Protein CT120) (Protein FAM57A) Homo sapiens (Human) lipid homeostasis [GO:0055088] GO:0005783; GO:0005886; GO:0055088 32822 XM_044322529.1 36 0 60 0 15 NA NA NA NA NA NA 32823 XM_029326950.2 0 1 19 25 32 P48733 9.92e-26 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Bos taurus (Bovine) antibacterial innate immune response [GO:0140367]; defense response to Gram-negative bacterium [GO:0050829] GO:0000922; GO:0005201; GO:0005509; GO:0005576; GO:0005929; GO:0016020; GO:0016323; GO:0016324; GO:0031012; GO:0050829; GO:0060170; GO:0140367 32824 XM_044309362.1 2 4 1 5 16 NA NA NA NA NA NA 32825 XM_029332616.2 0 0 0 61 0 P49337 4.58e-67 Protein Wnt-4 Gallus gallus (Chicken) canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; kidney morphogenesis [GO:0060993]; negative regulation of androgen biosynthetic process [GO:2000180]; neuron differentiation [GO:0030182]; positive regulation of cartilage development [GO:0061036]; positive regulation of skeletal muscle cell proliferation [GO:0014858]; positive regulation of skeletal muscle fiber differentiation [GO:1902811] GO:0005109; GO:0005125; GO:0005615; GO:0005737; GO:0014858; GO:0030182; GO:0045165; GO:0060070; GO:0060993; GO:0061036; GO:1902811; GO:2000180 32826 XM_029339173.2 3247 2560 1556 4062 3675 NA NA NA NA NA NA 32827 XM_029338440.2 1929 1726 1377 2780 2280 NA NA NA NA NA NA 32828 XM_044318560.1 0 53 16 40 135 Q68F72 3.1e-82 Solute carrier family 15 member 4 Xenopus laevis (African clawed frog) dipeptide import across plasma membrane [GO:0140206]; innate immune response [GO:0045087]; mast cell homeostasis [GO:0033023]; peptidoglycan transport [GO:0015835]; positive regulation of innate immune response [GO:0045089]; positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [GO:0070430]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of toll-like receptor 7 signaling pathway [GO:0034157]; positive regulation of toll-like receptor 8 signaling pathway [GO:0034161]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; protein transport [GO:0015031]; regulation of isotype switching to IgG isotypes [GO:0048302]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424] GO:0005290; GO:0005765; GO:0015031; GO:0015333; GO:0015647; GO:0015835; GO:0031901; GO:0033023; GO:0034157; GO:0034161; GO:0034165; GO:0036020; GO:0045087; GO:0045089; GO:0048302; GO:0070424; GO:0070430; GO:0070434; GO:0071916; GO:0140206 32829 XR_006391471.1 64 97 285 76 166 NA NA NA NA NA NA 32830 XM_029339912.2 1206 1254 975 1215 1337 NA NA NA NA NA NA 32831 XM_044316074.1 0 0 9 6 6 NA NA NA NA NA NA 32832 XM_029344598.2 9318 18471 9385 9507 7378 Q9D4P0 1.06e-95 ADP-ribosylation factor-like protein 5B (ADP-ribosylation factor-like protein 8) Mus musculus (Mouse) intracellular protein transport [GO:0006886]; protein localization to Golgi membrane [GO:1903292]; vesicle-mediated transport [GO:0016192] GO:0003924; GO:0005525; GO:0005737; GO:0005802; GO:0006886; GO:0016192; GO:1903292 32833 XR_006394443.1 534 273 13 132 160 NA NA NA NA NA NA 32834 XM_029357622.2 397 90 310 351 276 NA NA NA NA NA NA 32835 XR_006391399.1 181 219 24 260 479 NA NA NA NA NA NA 32836 XM_044321452.1 75 0 12 0 0 O43900 3.34e-130 Prickle planar cell polarity protein 3 (LIM domain only protein 6) (LMO-6) (Prickle-like protein 3) (Pk3) (Triple LIM domain protein 6) Homo sapiens (Human) cell projection organization [GO:0030030] GO:0005739; GO:0005886; GO:0008270; GO:0030030 32837 XR_006392855.1 0 0 18 5 3 NA NA NA NA NA NA 32838 XM_029351378.2 104 828 137 788 508 Q2KIN6 2.04e-42 Protein Mpv17 Bos taurus (Bovine) regulation of mitochondrial DNA metabolic process [GO:1901858] GO:0005737; GO:0005743; GO:0015267; GO:1901858 32839 XM_029329164.2 2199 2249 1231 1553 1522 B2KI79 3.18e-59 Dolichyldiphosphatase 1 (EC 3.6.1.43) (Dolichyl pyrophosphate phosphatase 1) Rhinolophus ferrumequinum (Greater horseshoe bat) protein N-linked glycosylation [GO:0006487] GO:0005789; GO:0006487; GO:0047874 32840 XM_044328274.1 13 30 16 23 12 NA NA NA NA NA NA 32841 XM_029355817.2 337 298 197 647 194 NA NA NA NA NA NA 32842 XM_029339721.2 529 0 0 511 10 Q7Z7A1 5.11e-79 Centriolin (Centrosomal protein 1) (Centrosomal protein of 110 kDa) (Cep110) Homo sapiens (Human) aorta development [GO:0035904]; cell cycle [GO:0007049]; cell division [GO:0051301]; coronary vasculature development [GO:0060976]; kidney development [GO:0001822]; ventricular septum development [GO:0003281] GO:0001822; GO:0003281; GO:0005813; GO:0005815; GO:0005829; GO:0007049; GO:0016020; GO:0034451; GO:0035904; GO:0048471; GO:0051301; GO:0060976; GO:0090543; GO:0090619; GO:0097431; GO:0120103 32843 XM_044318260.1 114 135 86 117 183 E7FAM5 5.06e-90 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 32844 XM_044307877.1 118 9 82 111 118 NA NA NA NA NA NA 32845 XM_044310558.1 7 4 1 12 180 Q9VBW3 1.04e-61 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 32846 XM_029337761.2 547 462 321 611 658 O88866 1.65e-113 Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (Serine/threonine-protein kinase MAK-V) Mus musculus (Mouse) intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468] GO:0004672; GO:0004674; GO:0005524; GO:0006468; GO:0035556; GO:0106310 32847 XM_044315447.1 0 0 9 14 0 NA NA NA NA NA NA 32848 XM_044322822.1 903 811 473 1227 851 Q9CR50 1.92e-27 RING finger and CHY zinc finger domain-containing protein 1 (EC 2.3.2.27) (Androgen receptor N-terminal-interacting protein) (CH-rich-interacting match with PLAG1) (E3 ubiquitin-protein ligase Pirh2) (RING-type E3 ubiquitin transferase RCHY1) (Zinc finger protein 363) Mus musculus (Mouse) positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; protein autoubiquitination [GO:0051865]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000151; GO:0002039; GO:0005102; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006511; GO:0008270; GO:0016567; GO:0016607; GO:0031398; GO:0032436; GO:0042803; GO:0043231; GO:0051865; GO:0061630 32849 XR_006393391.1 1282 1012 1018 1306 892 NA NA NA NA NA NA 32850 XM_044319096.1 1792 1069 961 1703 1185 Q96KP1 0 Exocyst complex component 2 (Exocyst complex component Sec5) Homo sapiens (Human) exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; membrane fission [GO:0090148]; mitotic cytokinesis [GO:0000281]; protein transport [GO:0015031]; regulation of entry of bacterium into host cell [GO:2000535]; vesicle docking involved in exocytosis [GO:0006904]; vesicle tethering involved in exocytosis [GO:0090522] GO:0000145; GO:0000281; GO:0005829; GO:0005886; GO:0006887; GO:0006893; GO:0006904; GO:0015031; GO:0016020; GO:0019901; GO:0031267; GO:0047485; GO:0090148; GO:0090522; GO:0090543; GO:2000535 32851 XM_044307099.1 30 9 20 11 64 NA NA NA NA NA NA 32852 XR_006394894.1 1 9 9 103 3 NA NA NA NA NA NA 32853 XM_044318830.1 0 0 0 0 397 Q5R9T9 2.12e-47 Guanylate-binding protein 6 (EC 3.6.5.-) (GTP-binding protein 6) (GBP-6) (Guanine nucleotide-binding protein 6) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cellular response to type II interferon [GO:0071346]; defense response to bacterium [GO:0042742]; immune response [GO:0006955] GO:0003924; GO:0005525; GO:0006955; GO:0031410; GO:0042742; GO:0071346 32854 XM_029339131.2 211 0 33 24 140 B2GUE2 1.43e-45 Leucine-rich repeat flightless-interacting protein 2 (LRR FLII-interacting protein 2) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) dorsal/ventral axis specification [GO:0009950]; regulation of DNA-templated transcription [GO:0006355]; Wnt signaling pathway [GO:0016055] GO:0006355; GO:0009950; GO:0016055; GO:0030275 32855 XM_044329035.1 93 42 28 135 212 Q8K2J9 3.93e-76 BTB/POZ domain-containing protein 6 Mus musculus (Mouse) neurogenesis [GO:0022008] GO:0005829; GO:0022008 32856 XM_029358452.2 11 21 37 0 70 P49582 3.44e-80 Neuronal acetylcholine receptor subunit alpha-7 Mus musculus (Mouse) acetylcholine receptor signaling pathway [GO:0095500]; associative learning [GO:0008306]; B cell activation [GO:0042113]; behavioral response to ethanol [GO:0048149]; behavioral response to nicotine [GO:0035095]; calcium ion transport [GO:0006816]; chemical synaptic transmission [GO:0007268]; dendrite arborization [GO:0140059]; dendritic spine organization [GO:0097061]; endocytosis [GO:0006897]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; generation of ovulation cycle rhythm [GO:0060112]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; learning or memory [GO:0007611]; membrane depolarization [GO:0051899]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; modulation of excitatory postsynaptic potential [GO:0098815]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of tumor necrosis factor production [GO:0032720]; nervous system process [GO:0050877]; neuronal action potential [GO:0019228]; ovulation cycle [GO:0042698]; positive regulation of acetylcholine biosynthetic process [GO:1905923]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of CoA-transferase activity [GO:1905920]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure [GO:0001988]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of amyloid fibril formation [GO:1905906]; regulation of inflammatory response [GO:0050727]; regulation of membrane potential [GO:0042391]; regulation of neuron death [GO:1901214]; regulation of nitric oxide metabolic process [GO:0080164]; regulation of norepinephrine secretion [GO:0014061]; regulation of response to drug [GO:2001023]; regulation of synapse structural plasticity [GO:0051823]; regulation of synaptic transmission, cholinergic [GO:0032222]; regulation of synaptic transmission, dopaminergic [GO:0032225]; response to acetylcholine [GO:1905144]; response to amyloid-beta [GO:1904645]; response to cold [GO:0009409]; response to ethanol [GO:0045471]; response to food [GO:0032094]; response to nicotine [GO:0035094]; sensory processing [GO:0050893]; signal transduction [GO:0007165]; synapse organization [GO:0050808]; synaptic transmission, cholinergic [GO:0007271]; T cell activation [GO:0042110] GO:0001540; GO:0001933; GO:0001934; GO:0001988; GO:0005216; GO:0005231; GO:0005737; GO:0005886; GO:0005892; GO:0006811; GO:0006816; GO:0006897; GO:0007165; GO:0007268; GO:0007271; GO:0007611; GO:0007613; GO:0008179; GO:0008306; GO:0009409; GO:0009897; GO:0010628; GO:0014061; GO:0014069; GO:0015464; GO:0015643; GO:0016020; GO:0016324; GO:0017081; GO:0019228; GO:0019901; GO:0022848; GO:0030317; GO:0030424; GO:0030425; GO:0030426; GO:0030594; GO:0030673; GO:0032094; GO:0032222; GO:0032225; GO:0032279; GO:0032691; GO:0032715; GO:0032720; GO:0033138; GO:0034220; GO:0035094; GO:0035095; GO:0042110; GO:0042113; GO:0042166; GO:0042391; GO:0042698; GO:0042734; GO:0042803; GO:0043005; GO:0043025; GO:0043197; GO:0043198; GO:0044853; GO:0045121; GO:0045202; GO:0045211; GO:0045471; GO:0048149; GO:0050727; GO:0050728; GO:0050804; GO:0050808; GO:0050877; GO:0050893; GO:0051117; GO:0051247; GO:0051649; GO:0051823; GO:0051899; GO:0060112; GO:0070373; GO:0070374; GO:0080164; GO:0095500; GO:0097061; GO:0097110; GO:0098690; GO:0098793; GO:0098815; GO:0098897; GO:0098981; GO:0099171; GO:0099634; GO:0140059; GO:1900273; GO:1901214; GO:1902004; GO:1904315; GO:1904645; GO:1905144; GO:1905906; GO:1905920; GO:1905923; GO:2000463; GO:2001023 32857 XM_029349311.2 4465 3180 2635 4567 4475 Q3UXZ9 0 Lysine-specific demethylase 5A (EC 1.14.11.67) (Histone demethylase JARID1A) (Jumonji/ARID domain-containing protein 1A) (Retinoblastoma-binding protein 2) (RBBP-2) ([histone H3]-trimethyl-L-lysine(4) demethylase 5A) Mus musculus (Mouse) chromatin remodeling [GO:0006338]; circadian regulation of gene expression [GO:0032922]; facultative heterochromatin formation [GO:0140718]; histone H3-K4 demethylation [GO:0034720]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA-binding transcription factor activity [GO:0051090] GO:0000122; GO:0000976; GO:0003677; GO:0003682; GO:0003713; GO:0004857; GO:0005634; GO:0005730; GO:0006338; GO:0008270; GO:0031490; GO:0032452; GO:0032453; GO:0032922; GO:0032993; GO:0034647; GO:0034720; GO:0035064; GO:0042393; GO:0045893; GO:0051090; GO:0140718 32858 XM_044323721.1 0 0 0 0 27 NA NA NA NA NA NA 32859 XM_029331562.2 925 346 498 695 800 Q498R1 7.78e-134 Methionine synthase reductase (MSR) (EC 1.16.1.8) (Aquacobalamin reductase) (AqCbl reductase) Rattus norvegicus (Rat) cobalamin metabolic process [GO:0009235]; DNA methylation [GO:0006306]; folic acid metabolic process [GO:0046655]; homocysteine catabolic process [GO:0043418]; homocysteine metabolic process [GO:0050667]; methionine biosynthetic process [GO:0009086]; negative regulation of cystathionine beta-synthase activity [GO:1904042]; regulation of apoptotic process [GO:0042981]; S-adenosylmethionine cycle [GO:0033353] GO:0003958; GO:0005654; GO:0005829; GO:0006306; GO:0009086; GO:0009235; GO:0010181; GO:0016491; GO:0016723; GO:0030586; GO:0033353; GO:0042981; GO:0043418; GO:0045111; GO:0046655; GO:0050660; GO:0050667; GO:0070402; GO:0071949; GO:1904042 32860 XM_029331562.2 925 346 498 695 800 Q498R1 1.43e-46 Methionine synthase reductase (MSR) (EC 1.16.1.8) (Aquacobalamin reductase) (AqCbl reductase) Rattus norvegicus (Rat) cobalamin metabolic process [GO:0009235]; DNA methylation [GO:0006306]; folic acid metabolic process [GO:0046655]; homocysteine catabolic process [GO:0043418]; homocysteine metabolic process [GO:0050667]; methionine biosynthetic process [GO:0009086]; negative regulation of cystathionine beta-synthase activity [GO:1904042]; regulation of apoptotic process [GO:0042981]; S-adenosylmethionine cycle [GO:0033353] GO:0003958; GO:0005654; GO:0005829; GO:0006306; GO:0009086; GO:0009235; GO:0010181; GO:0016491; GO:0016723; GO:0030586; GO:0033353; GO:0042981; GO:0043418; GO:0045111; GO:0046655; GO:0050660; GO:0050667; GO:0070402; GO:0071949; GO:1904042 32861 XM_044312473.1 0 0 4 21 17 Q5SVZ6 2.29e-57 Zinc finger MYM-type protein 1 Homo sapiens (Human) NA GO:0005634; GO:0008270; GO:0046983 32862 XM_044316171.1 0 37 47 3 1 NA NA NA NA NA NA 32863 XM_029355559.2 8502 15571 5826 9652 7467 Q98TR7 5.31e-69 40S ribosomal protein S16 Heteropneustes fossilis (Stinging catfish) translation [GO:0006412] GO:0003735; GO:0005840; GO:0006412; GO:1990904 32864 XM_029352491.2 34 4 11 6 108 Q09575 1.52e-27 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 32865 XM_044324953.1 32 66 20 28 60 NA NA NA NA NA NA 32866 XM_044319253.1 832 265 274 181 568 NA NA NA NA NA NA 32867 XM_029339132.2 1986 1836 1020 1734 1680 B2GUE2 1.93e-46 Leucine-rich repeat flightless-interacting protein 2 (LRR FLII-interacting protein 2) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) dorsal/ventral axis specification [GO:0009950]; regulation of DNA-templated transcription [GO:0006355]; Wnt signaling pathway [GO:0016055] GO:0006355; GO:0009950; GO:0016055; GO:0030275 32868 XM_029337874.2 1858 1514 1106 1903 1840 O70439 7.06e-31 Syntaxin-7 Mus musculus (Mouse) endosome to lysosome transport [GO:0008333]; intracellular protein transport [GO:0006886]; organelle assembly [GO:0070925]; organelle localization [GO:0051640]; positive regulation of receptor localization to synapse [GO:1902685]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; regulation of protein localization to plasma membrane [GO:1903076]; vesicle docking [GO:0048278]; vesicle fusion [GO:0006906]; vesicle-mediated transport [GO:0016192] GO:0000149; GO:0001772; GO:0001916; GO:0005484; GO:0005764; GO:0005765; GO:0005768; GO:0005769; GO:0005770; GO:0005886; GO:0006886; GO:0006906; GO:0008021; GO:0008333; GO:0012505; GO:0016020; GO:0016192; GO:0019869; GO:0019905; GO:0030139; GO:0030672; GO:0031201; GO:0031901; GO:0031902; GO:0031982; GO:0042582; GO:0044877; GO:0048278; GO:0048471; GO:0051640; GO:0055037; GO:0070820; GO:0070925; GO:1902685; GO:1903076 32869 XM_029345114.2 41 0 11 53 88 NA NA NA NA NA NA 32870 XM_029351540.2 1573 1049 966 1341 1466 Q05090 0 Kinesin light chain (KLC) Strongylocentrotus purpuratus (Purple sea urchin) microtubule-based movement [GO:0007018] GO:0005737; GO:0005871; GO:0005874; GO:0007018; GO:0019894 32871 XM_044308172.1 2813 3301 2228 4692 5147 Q9K9H0 0 Isocitrate lyase (ICL) (EC 4.1.3.1) (Isocitrase) (Isocitratase) Halalkalibacterium halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) (Bacillus halodurans) glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099] GO:0004451; GO:0006097; GO:0006099; GO:0046872 32872 XM_044328519.1 334 38 62 39 81 Q9NVV5 6.82e-43 Androgen-induced gene 1 protein (AIG-1) (Fatty acid esters of hydroxy fatty acids hydrolase AIG1) (FAHFA hydrolase AIG1) (EC 3.1.-.-) Homo sapiens (Human) long-chain fatty acid catabolic process [GO:0042758] GO:0005886; GO:0012505; GO:0016020; GO:0016787; GO:0042758 32873 XM_044321787.1 43 0 11 168 220 NA NA NA NA NA NA 32874 XM_029351829.2 474 636 372 722 534 Q6TDP4 4.26e-131 Kelch-like protein 17 (Actinfilin) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; protein ubiquitination [GO:0016567]; regulation protein catabolic process at postsynapse [GO:0140252] GO:0005615; GO:0007420; GO:0014069; GO:0015629; GO:0016567; GO:0030036; GO:0031208; GO:0032839; GO:0043025; GO:0051015; GO:0060090; GO:0098978; GO:0140252 32875 XM_029351829.2 474 636 372 722 534 Q6TDP4 1.36e-36 Kelch-like protein 17 (Actinfilin) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; protein ubiquitination [GO:0016567]; regulation protein catabolic process at postsynapse [GO:0140252] GO:0005615; GO:0007420; GO:0014069; GO:0015629; GO:0016567; GO:0030036; GO:0031208; GO:0032839; GO:0043025; GO:0051015; GO:0060090; GO:0098978; GO:0140252 32876 XR_006394814.1 49 5 31 18 11 Q11126 3.57e-37 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3 (EC 2.4.1.65) (4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase) (EC 2.4.1.152) (Alpha-3-fucosyltransferase FUT3) (EC 2.4.1.-) (Blood group Lewis alpha-4-fucosyltransferase) (Lewis FT) (FUTB) (Fucosyltransferase 3) (Fucosyltransferase III) (FucT-III) Bos taurus (Bovine) fucosylation [GO:0036065]; lipid metabolic process [GO:0006629]; oligosaccharide metabolic process [GO:0009311]; positive regulation of cell-cell adhesion [GO:0022409]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127] GO:0006487; GO:0006493; GO:0006629; GO:0009311; GO:0017060; GO:0017083; GO:0022409; GO:0030334; GO:0032580; GO:0036065; GO:0042127; GO:0046920 32877 XR_006394814.1 49 5 31 18 11 Q11126 3.57e-37 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3 (EC 2.4.1.65) (4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase) (EC 2.4.1.152) (Alpha-3-fucosyltransferase FUT3) (EC 2.4.1.-) (Blood group Lewis alpha-4-fucosyltransferase) (Lewis FT) (FUTB) (Fucosyltransferase 3) (Fucosyltransferase III) (FucT-III) Bos taurus (Bovine) fucosylation [GO:0036065]; lipid metabolic process [GO:0006629]; oligosaccharide metabolic process [GO:0009311]; positive regulation of cell-cell adhesion [GO:0022409]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127] GO:0006487; GO:0006493; GO:0006629; GO:0009311; GO:0017060; GO:0017083; GO:0022409; GO:0030334; GO:0032580; GO:0036065; GO:0042127; GO:0046920 32878 XM_029337532.2 58 0 0 0 0 Q9YHV3 5.17e-33 Noggin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cartilage development [GO:0051216]; cloaca development [GO:0035844]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic viscerocranium morphogenesis [GO:0048703]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell differentiation [GO:0045596]; osteoblast differentiation [GO:0001649]; pronephros development [GO:0048793] GO:0001649; GO:0005615; GO:0007368; GO:0009953; GO:0030514; GO:0035844; GO:0045596; GO:0048703; GO:0048793; GO:0051216 32879 XM_044325407.1 0 2 0 7 0 Q6Q629 1.04e-115 Inactive dipeptidyl peptidase 10 (Dipeptidyl peptidase X) (DPP X) (Kv4 potassium channel auxiliary subunit) Rattus norvegicus (Rat) positive regulation of protein localization to plasma membrane [GO:1903078]; protein localization to plasma membrane [GO:0072659]; proteolysis [GO:0006508]; regulation of potassium ion transmembrane transport [GO:1901379] GO:0005886; GO:0006508; GO:0008076; GO:0008236; GO:0015459; GO:0016020; GO:0044325; GO:0072659; GO:1901379; GO:1903078 32880 XM_029344861.2 324 199 148 223 234 NA NA NA NA NA NA 32881 XM_044323380.1 12 0 7 6 47 Q9LHQ6 7.05e-58 Organic cation/carnitine transporter 4 (AtOCT4) Arabidopsis thaliana (Mouse-ear cress) cellular response to water deprivation [GO:0042631]; ion transport [GO:0006811] GO:0005524; GO:0006811; GO:0009535; GO:0009705; GO:0022857; GO:0042631 32882 XM_029330716.2 0 230 85 0 0 P56377 1.01e-87 AP-1 complex subunit sigma-2 (Adaptor protein complex AP-1 subunit sigma-1B) (Adaptor-related protein complex 1 subunit sigma-1B) (Clathrin assembly protein complex 1 sigma-1B small chain) (Golgi adaptor HA1/AP1 adaptin sigma-1B subunit) (Sigma 1B subunit of AP-1 clathrin) (Sigma-adaptin 1B) (Sigma1B-adaptin) Homo sapiens (Human) intracellular protein transport [GO:0006886]; melanosome assembly [GO:1903232]; platelet dense granule organization [GO:0060155]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0005765; GO:0005769; GO:0005794; GO:0005829; GO:0005905; GO:0006886; GO:0016192; GO:0030119; GO:0030121; GO:0030659; GO:0032588; GO:0035615; GO:0043231; GO:0060155; GO:1903232 32883 XM_029348738.2 368 201 213 251 337 Q8IWL3 2.51e-36 Iron-sulfur cluster co-chaperone protein HscB (DnaJ homolog subfamily C member 20) [Cleaved into: Iron-sulfur cluster co-chaperone protein HscB, cytoplasmic (C-HSC20); Iron-sulfur cluster co-chaperone protein HscB, mitochondrial] Homo sapiens (Human) [2Fe-2S] cluster assembly [GO:0044571]; iron-sulfur cluster assembly [GO:0016226]; primitive erythrocyte differentiation [GO:0060319]; primitive hemopoiesis [GO:0060215]; protein complex oligomerization [GO:0051259] GO:0001671; GO:0005654; GO:0005737; GO:0005739; GO:0005829; GO:0016226; GO:0042802; GO:0044571; GO:0046872; GO:0051087; GO:0051259; GO:0060215; GO:0060319 32884 XM_044311593.1 112 29 33 65 77 NA NA NA NA NA NA 32885 XR_006394104.1 12 76 36 26 69 NA NA NA NA NA NA 32886 XR_003826057.2 731 1307 587 440 829 NA NA NA NA NA NA 32887 XM_029339754.2 16 26 0 0 0 Q767K8 3.21e-26 28S ribosomal protein S18b, mitochondrial (MRP-S18-b) (Mrps18-b) (S18mt-b) (28S ribosomal protein S18-2, mitochondrial) (MRP-S18-2) Sus scrofa (Pig) mitochondrial translation [GO:0032543] GO:0003735; GO:0005654; GO:0005739; GO:0005763; GO:0030054; GO:0032543 32888 XM_029339726.2 326 242 234 661 538 NA NA NA NA NA NA 32889 XM_029355347.2 95 204 26 387 0 O15439 0 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 32890 XM_044314646.1 0 0 9 0 4 Q96AY4 1.96e-171 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32891 XM_044314646.1 0 0 9 0 4 Q96AY4 1.68e-159 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32892 XM_044314646.1 0 0 9 0 4 Q96AY4 1.15e-139 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32893 XM_044314646.1 0 0 9 0 4 Q96AY4 7.76e-131 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32894 XM_044314646.1 0 0 9 0 4 Q96AY4 6.13e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32895 XM_029343007.2 26059 35941 8691 12442 11137 P26642 6.98e-163 Elongation factor 1-gamma-A (EF-1-gamma-A) (eEF-1B gamma-A) (p47) Xenopus laevis (African clawed frog) NA GO:0003746 32896 XM_044311253.1 0 8 0 36 22 NA NA NA NA NA NA 32897 XM_029349672.2 10 0 31 8 28 NA NA NA NA NA NA 32898 XM_029335729.2 24 62 18 8 38 Q9HD40 0 O-phosphoseryl-tRNA(Sec) selenium transferase (EC 2.9.1.2) (Liver-pancreas antigen) (LP) (SLA-p35) (SLA/LP autoantigen) (Selenocysteine synthase) (Sec synthase) (Selenocysteinyl-tRNA(Sec) synthase) (Sep-tRNA:Sec-tRNA synthase) (SepSecS) (Soluble liver antigen) (SLA) (UGA suppressor tRNA-associated protein) (tRNA(Ser/Sec)-associated antigenic protein) Homo sapiens (Human) selenocysteine incorporation [GO:0001514]; selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056] GO:0000049; GO:0001514; GO:0005634; GO:0005737; GO:0005829; GO:0097056; GO:0098621 32899 XM_029335252.2 552 447 415 579 534 Q9BQ70 8.55e-150 Transcription factor 25 (TCF-25) (Nuclear localized protein 1) Homo sapiens (Human) heart development [GO:0007507]; negative regulation of transcription by RNA polymerase II [GO:0000122] GO:0000122; GO:0003677; GO:0003714; GO:0005634; GO:0007507; GO:1990112 32900 XM_029338694.2 33 0 464 5 119 NA NA NA NA NA NA 32901 XM_044317015.1 11 41 6 26 42 Q9N126 1.86e-64 Retinol dehydrogenase 8 (EC 1.1.1.300) (Photoreceptor outer segment all-trans retinol dehydrogenase) Bos taurus (Bovine) estrogen biosynthetic process [GO:0006703]; response to stimulus [GO:0050896]; retinol metabolic process [GO:0042572]; visual perception [GO:0007601] GO:0004303; GO:0004745; GO:0005829; GO:0006703; GO:0007601; GO:0016491; GO:0042572; GO:0042622; GO:0050896; GO:0052650 32902 XM_029341206.2 400 729 344 584 183 P41969 7.73e-26 ETS domain-containing protein Elk-1 Mus musculus (Mouse) cell differentiation [GO:0030154]; cellular response to gamma radiation [GO:0071480]; cellular response to lipid [GO:0071396]; cellular response to testosterone stimulus [GO:0071394]; gene expression [GO:0010467]; liver development [GO:0001889]; lung development [GO:0030324]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of neuron death [GO:1901216]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; response to fibroblast growth factor [GO:0071774]; response to light stimulus [GO:0009416] GO:0000976; GO:0000978; GO:0000981; GO:0001228; GO:0001889; GO:0003682; GO:0003690; GO:0003700; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0006355; GO:0006357; GO:0009416; GO:0010467; GO:0030154; GO:0030324; GO:0030374; GO:0030425; GO:0043025; GO:0043679; GO:0045893; GO:0045944; GO:0061629; GO:0071394; GO:0071396; GO:0071480; GO:0071774; GO:1901216; GO:1990837 32903 XM_044310663.1 629 237 160 268 341 NA NA NA NA NA NA 32904 XM_044320866.1 0 43 0 0 240 Q96PM5 2.56e-28 RING finger and CHY zinc finger domain-containing protein 1 (EC 2.3.2.27) (Androgen receptor N-terminal-interacting protein) (CH-rich-interacting match with PLAG1) (E3 ubiquitin-protein ligase Pirh2) (RING finger protein 199) (RING-type E3 ubiquitin transferase RCHY1) (Zinc finger protein 363) (p53-induced RING-H2 protein) (hPirh2) Homo sapiens (Human) error-free translesion synthesis [GO:0070987]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; protein autoubiquitination [GO:0051865]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000151; GO:0002039; GO:0004842; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006511; GO:0008270; GO:0016567; GO:0016607; GO:0031398; GO:0032436; GO:0042803; GO:0043231; GO:0051865; GO:0061630; GO:0070987 32905 XR_003824412.2 56 0 0 0 0 NA NA NA NA NA NA 32906 XM_029336064.2 2720 2307 1266 2228 1464 Q5RC74 2.95e-134 Derlin-2 (Der1-like protein 2) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) endoplasmic reticulum unfolded protein response [GO:0030968]; negative regulation of retrograde protein transport, ER to cytosol [GO:1904153]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; retrograde protein transport, ER to cytosol [GO:0030970]; suckling behavior [GO:0001967]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0001967; GO:0005047; GO:0005769; GO:0005770; GO:0005789; GO:0008284; GO:0030307; GO:0030433; GO:0030968; GO:0030970; GO:1904153 32907 XM_029339622.2 9 83 40 0 16 NA NA NA NA NA NA 32908 XM_029338452.2 156 0 0 0 0 Q1JQC1 1.45e-41 Major facilitator superfamily domain-containing protein 1 Bos taurus (Bovine) protein localization to lysosome [GO:0061462]; protein stabilization [GO:0050821] GO:0005764; GO:0005765; GO:0022857; GO:0042803; GO:0050821; GO:0061462 32909 XM_029331611.2 1998 3044 1435 2827 1013 NA NA NA NA NA NA 32910 XM_029330554.2 87 209 100 101 112 Q8BG93 3.18e-40 Nucleotide triphosphate diphosphatase NUDT15 (EC 3.6.1.9) (MutT homolog 2) (mMTH2) (Nucleoside diphosphate-linked moiety X motif 15) (Nudix motif 15) (Nucleoside diphosphate-linked to another moiety X hydrolase 15) (Nudix hydrolase 15) Mus musculus (Mouse) dGTP catabolic process [GO:0006203]; DNA protection [GO:0042262]; mitotic cell cycle [GO:0000278]; nucleoside phosphate catabolic process [GO:1901292]; purine deoxyribonucleoside triphosphate catabolic process [GO:0009217]; purine nucleotide catabolic process [GO:0006195]; regulation of proteasomal protein catabolic process [GO:0061136]; response to reactive oxygen species [GO:0000302]; xenobiotic catabolic process [GO:0042178] GO:0000278; GO:0000302; GO:0005829; GO:0006195; GO:0006203; GO:0008413; GO:0009217; GO:0035539; GO:0042178; GO:0042262; GO:0044715; GO:0046872; GO:0047429; GO:0061136; GO:1901292 32911 XM_044317345.1 246 0 236 236 275 Q9Y4E6 0 WD repeat-containing protein 7 (Rabconnectin-3 beta) (TGF-beta resistance-associated protein TRAG) Homo sapiens (Human) hematopoietic progenitor cell differentiation [GO:0002244] GO:0002244; GO:0005737 32912 XM_044319617.1 78 80 277 195 1 NA NA NA NA NA NA 32913 XM_044319260.1 24 0 0 0 0 Q86W24 2.18e-42 NACHT, LRR and PYD domains-containing protein 14 (Nucleotide-binding oligomerization domain protein 5) Homo sapiens (Human) cell differentiation [GO:0030154]; regulation of inflammatory response [GO:0050727]; spermatogenesis [GO:0007283] GO:0005524; GO:0005737; GO:0007283; GO:0030154; GO:0050727 32914 XM_044320927.1 22 0 4 23 105 NA NA NA NA NA NA 32915 XM_029346478.2 923 897 454 968 679 Q6DHC3 1.68e-104 Probable mitochondrial glutathione transporter SLC25A40 (Solute carrier family 25 member 40) Danio rerio (Zebrafish) (Brachydanio rerio) mitochondrial transmembrane transport [GO:1990542] GO:0005739; GO:0005743; GO:1990542 32916 XM_029330340.2 1900 1369 925 1716 1428 NA NA NA NA NA NA 32917 XM_029336336.2 10280 7845 5096 5097 5386 O02703 4.72e-22 Apoptosis regulator BAX Bos taurus (Bovine) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; apoptotic mitochondrial changes [GO:0008637]; apoptotic signaling pathway [GO:0097190]; B cell apoptotic process [GO:0001783]; establishment or maintenance of transmembrane electrochemical gradient [GO:0010248]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; mitochondrial fusion [GO:0008053]; negative regulation of mitochondrial membrane potential [GO:0010917]; negative regulation of protein binding [GO:0032091]; positive regulation of apoptotic process [GO:0043065]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein-containing complex assembly [GO:0031334]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; regulation of apoptotic process [GO:0042981]; regulation of mitochondrial membrane potential [GO:0051881]; release of cytochrome c from mitochondria [GO:0001836]; release of matrix enzymes from mitochondria [GO:0032976]; response to toxic substance [GO:0009636] GO:0001783; GO:0001836; GO:0005634; GO:0005737; GO:0005739; GO:0005741; GO:0005757; GO:0005783; GO:0005789; GO:0005829; GO:0006919; GO:0008053; GO:0008289; GO:0008630; GO:0008635; GO:0008637; GO:0009636; GO:0010248; GO:0010917; GO:0015267; GO:0031334; GO:0032091; GO:0032976; GO:0042803; GO:0042981; GO:0043065; GO:0043525; GO:0043653; GO:0046930; GO:0046982; GO:0051434; GO:0051881; GO:0070059; GO:0090200; GO:0097136; GO:0097144; GO:0097190; GO:0097192; GO:0097193; GO:1900103; GO:2001244 32918 XR_006396946.1 384 110 105 152 99 NA NA NA NA NA NA 32919 XM_044306861.1 497 31 0 0 0 B3EWY9 0 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 32920 XM_044306861.1 497 31 0 0 0 B3EWY9 1.11e-101 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 32921 XM_044325150.1 31 17 20 0 96 Q86YA3 0 Protein ZGRF1 (GRF-type zinc finger domain-containing protein 1) Homo sapiens (Human) replication fork reversal [GO:0071932] GO:0003723; GO:0004386; GO:0005737; GO:0008270; GO:0016020; GO:0017108; GO:0071932 32922 XM_044317388.1 711 302 50 33 46 NA NA NA NA NA NA 32923 XR_006394855.1 113 47 66 73 87 Q8K430 2.77e-37 Kelch-like protein 17 (Actinfilin) Rattus norvegicus (Rat) actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; protein ubiquitination [GO:0016567]; regulation protein catabolic process at postsynapse [GO:0140252] GO:0007420; GO:0014069; GO:0015629; GO:0016567; GO:0030036; GO:0031208; GO:0032839; GO:0043025; GO:0051015; GO:0060090; GO:0098794; GO:0098978; GO:0140252 32924 XM_029345606.2 158 33 7 76 48 O14662 1.72e-84 Syntaxin-16 (Syn16) Homo sapiens (Human) endocytic recycling [GO:0032456]; intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]; vesicle docking [GO:0048278]; vesicle fusion [GO:0006906] GO:0000139; GO:0000149; GO:0005484; GO:0005737; GO:0005794; GO:0005802; GO:0005829; GO:0005925; GO:0006886; GO:0006906; GO:0012505; GO:0016020; GO:0019905; GO:0030672; GO:0031201; GO:0031985; GO:0032456; GO:0032588; GO:0042147; GO:0043231; GO:0048278; GO:0048471 32925 XR_006391507.1 396 177 250 184 296 NA NA NA NA NA NA 32926 XM_029351858.2 1985 1036 1059 1508 1033 Q9NR99 1.16e-41 Matrix-remodeling-associated protein 5 (Adhesion protein with leucine-rich repeats and immunoglobulin domains related to perlecan) (Adlican) Homo sapiens (Human) response to transforming growth factor beta [GO:0071559] GO:0005201; GO:0005576; GO:0062023; GO:0070062; GO:0071559 32927 XM_029351858.2 1985 1036 1059 1508 1033 Q9NR99 1.38e-33 Matrix-remodeling-associated protein 5 (Adhesion protein with leucine-rich repeats and immunoglobulin domains related to perlecan) (Adlican) Homo sapiens (Human) response to transforming growth factor beta [GO:0071559] GO:0005201; GO:0005576; GO:0062023; GO:0070062; GO:0071559 32928 XM_029351858.2 1985 1036 1059 1508 1033 Q9NR99 1.65e-29 Matrix-remodeling-associated protein 5 (Adhesion protein with leucine-rich repeats and immunoglobulin domains related to perlecan) (Adlican) Homo sapiens (Human) response to transforming growth factor beta [GO:0071559] GO:0005201; GO:0005576; GO:0062023; GO:0070062; GO:0071559 32929 XM_029351858.2 1985 1036 1059 1508 1033 Q9NR99 6.33e-28 Matrix-remodeling-associated protein 5 (Adhesion protein with leucine-rich repeats and immunoglobulin domains related to perlecan) (Adlican) Homo sapiens (Human) response to transforming growth factor beta [GO:0071559] GO:0005201; GO:0005576; GO:0062023; GO:0070062; GO:0071559 32930 XM_029351858.2 1985 1036 1059 1508 1033 Q9NR99 7.99e-28 Matrix-remodeling-associated protein 5 (Adhesion protein with leucine-rich repeats and immunoglobulin domains related to perlecan) (Adlican) Homo sapiens (Human) response to transforming growth factor beta [GO:0071559] GO:0005201; GO:0005576; GO:0062023; GO:0070062; GO:0071559 32931 XM_044326738.1 129 380 123 75 60 NA NA NA NA NA NA 32932 XM_029347851.2 0 0 22 52 0 Q96DM1 9.36e-65 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 32933 XM_029342931.2 377 285 305 203 146 Q91754 2.29e-131 Glucokinase regulatory protein (GKRP) (Glucokinase regulator) Xenopus laevis (African clawed frog) carbohydrate derivative metabolic process [GO:1901135]; carbohydrate metabolic process [GO:0005975]; negative regulation of glucokinase activity [GO:0033132] GO:0005654; GO:0005737; GO:0005739; GO:0005975; GO:0033132; GO:0070095; GO:1901135 32934 XM_029346380.2 71 38 37 38 56 NA NA NA NA NA NA 32935 XM_029332132.2 0 67 465 0 1491 NA NA NA NA NA NA 32936 XM_029358153.2 44 22 57 35 90 NA NA NA NA NA NA 32937 XM_029343078.2 13 32 29 12 23 Q5ZID2 2.3e-55 Programmed cell death protein 2-like Gallus gallus (Chicken) apoptotic process [GO:0006915] GO:0005737; GO:0006915 32938 XM_044325425.1 0 55 44 153 14 NA NA NA NA NA NA 32939 XM_029355910.2 1084 718 421 853 642 Q9NQE7 8.61e-98 Thymus-specific serine protease (EC 3.4.-.-) (Serine protease 16) Homo sapiens (Human) protein catabolic process [GO:0030163]; proteolysis [GO:0006508] GO:0005764; GO:0005768; GO:0006508; GO:0008236; GO:0008239; GO:0030163 32940 XM_029336887.2 769 112 316 1273 1964 P0CT39 2.19e-84 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 32941 XM_044314208.1 57 66 65 133 250 Q96AY4 2.74e-93 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32942 XM_044314208.1 57 66 65 133 250 Q96AY4 1.14e-86 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32943 XM_044314208.1 57 66 65 133 250 Q96AY4 1.14e-86 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32944 XM_044314208.1 57 66 65 133 250 Q96AY4 1.95e-86 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32945 XM_044314208.1 57 66 65 133 250 Q96AY4 3.04e-86 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32946 XM_044314208.1 57 66 65 133 250 Q96AY4 9.56e-85 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32947 XM_044314208.1 57 66 65 133 250 Q96AY4 3.03e-84 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32948 XM_044314208.1 57 66 65 133 250 Q96AY4 7.17e-83 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32949 XM_044314208.1 57 66 65 133 250 Q96AY4 9.44e-78 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32950 XM_044314208.1 57 66 65 133 250 Q96AY4 1.09e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32951 XM_044314208.1 57 66 65 133 250 Q96AY4 1.22e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32952 XM_029347191.2 70 173 156 197 191 NA NA NA NA NA NA 32953 XM_044311790.1 10 3 6 1 7 NA NA NA NA NA NA 32954 XM_044316027.1 11 3 20 11 53 NA NA NA NA NA NA 32955 XM_029327362.2 1570 933 659 1015 970 Q5ZL34 5.79e-36 Cleavage and polyadenylation specificity factor subunit 6 Gallus gallus (Chicken) messenger ribonucleoprotein complex assembly [GO:1990120]; mRNA alternative polyadenylation [GO:0110104]; positive regulation of RNA export from nucleus [GO:0046833]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; protein heterotetramerization [GO:0051290] GO:0003729; GO:0005634; GO:0005654; GO:0005726; GO:0005737; GO:0005847; GO:0005849; GO:0016607; GO:0035061; GO:0042382; GO:0046833; GO:0051290; GO:0098789; GO:0110104; GO:1990120 32956 XM_029332634.2 392 414 250 295 421 Q99K74 3.86e-85 Mediator of RNA polymerase II transcription subunit 24 (Mediator complex subunit 24) (Thyroid hormone receptor-associated protein 4) (Thyroid hormone receptor-associated protein complex 100 kDa component) (Trap100) (mTRAP100) Mus musculus (Mouse) positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; protein ubiquitination [GO:0016567]; RNA polymerase II preinitiation complex assembly [GO:0051123]; somatic stem cell population maintenance [GO:0035019]; transcription by RNA polymerase II [GO:0006366] GO:0000151; GO:0003712; GO:0003713; GO:0004402; GO:0005634; GO:0005654; GO:0006366; GO:0016567; GO:0016592; GO:0032968; GO:0035019; GO:0044877; GO:0045893; GO:0046966; GO:0051123; GO:0060261; GO:0061630; GO:0070847 32957 XM_029331992.2 2107 2054 1291 1610 1022 Q0P5B7 2.15e-45 Arylacetamide deacetylase (EC 3.1.1.3) Bos taurus (Bovine) lipid metabolic process [GO:0006629]; positive regulation of triglyceride catabolic process [GO:0010898] GO:0004806; GO:0005789; GO:0006629; GO:0010898; GO:0017171 32958 XM_044315015.1 8 0 16 1 0 NA NA NA NA NA NA 32959 XM_044324410.1 203 177 137 117 291 NA NA NA NA NA NA 32960 XM_029334810.2 5971 4139 3604 5527 3022 NA NA NA NA NA NA 32961 XM_044328813.1 97 44 44 119 90 NA NA NA NA NA NA 32962 XM_029337718.2 62 101 31 84 222 Q9D4G9 7.07e-41 RecQ-mediated genome instability protein 1 Mus musculus (Mouse) DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; glucose homeostasis [GO:0042593]; multicellular organism growth [GO:0035264]; reduction of food intake in response to dietary excess [GO:0002023]; resolution of meiotic recombination intermediates [GO:0000712]; resolution of recombination intermediates [GO:0071139]; response to dietary excess [GO:0002021]; response to glucose [GO:0009749] GO:0000166; GO:0000712; GO:0000724; GO:0002021; GO:0002023; GO:0005634; GO:0005654; GO:0006260; GO:0009749; GO:0016604; GO:0031422; GO:0035264; GO:0042593; GO:0071139 32963 XM_029328958.2 1082 706 376 967 604 H9JW43 1.91e-83 Chitin deacetylase 8 (BmCDA8) (EC 3.5.1.41) (Chitin deacetylase 17) Bombyx mori (Silk moth) chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272] GO:0000272; GO:0004099; GO:0005615; GO:0006032; GO:0008270 32964 XM_029327079.2 192 33 54 69 92 Q8TEQ8 5.98e-153 GPI ethanolamine phosphate transferase 3 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class O protein) (PIG-O) Homo sapiens (Human) GPI anchor biosynthetic process [GO:0006506] GO:0005789; GO:0006506; GO:0016020; GO:0051377 32965 XM_044317403.1 0 165 178 100 19 NA NA NA NA NA NA 32966 XM_044313504.1 4 0 0 6 0 NA NA NA NA NA NA 32967 XM_029348927.2 1112 1009 715 842 744 Q9CQ22 1.53e-27 Ragulator complex protein LAMTOR1 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1) (Lipid raft adaptor protein p18) Mus musculus (Mouse) cellular response to amino acid stimulus [GO:0071230]; cholesterol homeostasis [GO:0042632]; endosomal transport [GO:0016197]; endosome organization [GO:0007032]; lysosome localization [GO:0032418]; lysosome organization [GO:0007040]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of TOR signaling [GO:0032008]; protein localization [GO:0008104]; regulation of cell growth [GO:0001558]; regulation of cholesterol efflux [GO:0010874]; regulation of cholesterol import [GO:0060620]; regulation of receptor recycling [GO:0001919]; TORC1 signaling [GO:0038202] GO:0001558; GO:0001919; GO:0005085; GO:0005764; GO:0005765; GO:0005886; GO:0007032; GO:0007040; GO:0008104; GO:0010874; GO:0016197; GO:0031902; GO:0032008; GO:0032418; GO:0038202; GO:0042632; GO:0043410; GO:0045121; GO:0051020; GO:0060090; GO:0060620; GO:0071230; GO:0071986 32968 XM_044312228.1 6 6 0 37 18 NA NA NA NA NA NA 32969 XM_029355134.2 911 447 349 392 535 NA NA NA NA NA NA 32970 XM_044329095.1 3680 3151 2011 2915 2985 Q503V0 4.6e-71 Charged multivesicular body protein 6 (Chromatin-modifying protein 6) Danio rerio (Zebrafish) (Brachydanio rerio) late endosome to vacuole transport via multivesicular body sorting pathway [GO:0032511]; protein transport [GO:0015031]; vesicle budding from membrane [GO:0006900] GO:0000815; GO:0005771; GO:0006900; GO:0015031; GO:0031902; GO:0032511 32971 XR_003827975.2 38 13 13 1 41 NA NA NA NA NA NA 32972 XM_044328300.1 0 113 0 70 0 Q6NVC5 0 Mitochondrial Rho GTPase 1-A (MIRO-1-A) (EC 3.6.5.-) (Ras homolog gene family member T1-A) Danio rerio (Zebrafish) (Brachydanio rerio) cellular homeostasis [GO:0019725]; mitochondrial outer membrane permeabilization [GO:0097345]; mitochondrion organization [GO:0007005]; mitochondrion transport along microtubule [GO:0047497]; regulation of mitochondrion organization [GO:0010821]; small GTPase mediated signal transduction [GO:0007264] GO:0003924; GO:0005509; GO:0005525; GO:0005739; GO:0005741; GO:0007005; GO:0007264; GO:0010821; GO:0019725; GO:0047497; GO:0097345 32973 XM_029349123.2 747 589 428 684 656 Q5U395 1.57e-103 CTD nuclear envelope phosphatase 1A (EC 3.1.3.16) (Serine/threonine-protein phosphatase dullard-A) Danio rerio (Zebrafish) (Brachydanio rerio) nuclear envelope organization [GO:0006998]; positive regulation of triglyceride biosynthetic process [GO:0010867]; protein dephosphorylation [GO:0006470] GO:0004721; GO:0004722; GO:0005635; GO:0005737; GO:0005789; GO:0006470; GO:0006998; GO:0010867; GO:0017018; GO:0031965; GO:0071595 32974 XM_029329832.2 47 7 20 12 57 NA NA NA NA NA NA 32975 XM_029334782.2 8 0 50 38 0 Q8WV07 8.17e-21 Protein LTO1 homolog (Oral cancer-overexpressed protein 1) (Tumor-amplified and overexpressed sequence 1) Homo sapiens (Human) protein maturation by [4Fe-4S] cluster transfer [GO:0106035]; ribosomal large subunit biogenesis [GO:0042273]; telomere maintenance [GO:0000723]; translational initiation [GO:0006413] GO:0000723; GO:0005634; GO:0006413; GO:0042273; GO:0106035 32976 XM_044324325.1 442 168 116 231 222 NA NA NA NA NA NA 32977 XM_044323531.1 46 9 78 57 45 NA NA NA NA NA NA 32978 XM_029342858.2 80 16 26 48 29 NA NA NA NA NA NA 32979 XM_029340127.2 223 125 108 359 155 Q9WUJ8 1.41e-38 Origin recognition complex subunit 6 Mus musculus (Mouse) DNA replication initiation [GO:0006270]; DNA-templated DNA replication [GO:0006261]; negative regulation of cell division [GO:0051782] GO:0000808; GO:0001650; GO:0003677; GO:0005654; GO:0005664; GO:0006261; GO:0006270; GO:0051782 32980 XM_044322636.1 4523 3093 2902 3237 4331 NA NA NA NA NA NA 32981 XM_044309374.1 2 12 8 0 16 NA NA NA NA NA NA 32982 XM_044307856.1 1457 1730 1082 2484 2776 Q2KJG3 0 Asparagine--tRNA ligase, cytoplasmic (EC 6.1.1.22) (Asparaginyl-tRNA synthetase) (AsnRS) Bos taurus (Bovine) asparaginyl-tRNA aminoacylation [GO:0006421] GO:0003676; GO:0004816; GO:0005524; GO:0005737; GO:0006421; GO:0031090 32983 XM_044319050.1 193 29 0 0 0 NA NA NA NA NA NA 32984 XM_029352293.2 91 102 125 137 171 Q9H0J4 1.01e-26 Glutamine-rich protein 2 Homo sapiens (Human) cell projection assembly [GO:0030031]; flagellated sperm motility [GO:0030317]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059] GO:0005737; GO:0030031; GO:0030317; GO:0031965; GO:0036126; GO:2000059 32985 XM_044317874.1 128 37 8 170 156 Q8CG08 3.01e-38 Collagen triple helix repeat-containing protein 1 Rattus norvegicus (Rat) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005581; GO:0005615; GO:0005737; GO:0016477; GO:0016528; GO:0017147; GO:0031012; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0090090; GO:0090103; GO:0090177 32986 XM_029335101.2 470 300 604 529 835 Q9Y6D9 8.85e-83 Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient 1-like protein 1) (MAD1-like protein 1) (Mitotic checkpoint MAD1 protein homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181) Homo sapiens (Human) attachment of mitotic spindle microtubules to kinetochore [GO:0051315]; cell division [GO:0051301]; cytoplasmic sequestering of protein [GO:0051220]; deactivation of mitotic spindle assembly checkpoint [GO:1902426]; mitotic spindle assembly checkpoint signaling [GO:0007094]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; regulation of metaphase plate congression [GO:0090235]; thymus development [GO:0048538] GO:0000776; GO:0000922; GO:0005634; GO:0005737; GO:0005813; GO:0005819; GO:0005829; GO:0007094; GO:0042130; GO:0042802; GO:0043515; GO:0044615; GO:0048538; GO:0051220; GO:0051301; GO:0051315; GO:0072686; GO:0090235; GO:0090267; GO:1902426; GO:1990706; GO:1990728 32987 XM_044306855.1 27 16 6 22 78 Q7TN88 5.86e-53 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 32988 XM_044306855.1 27 16 6 22 78 Q7TN88 5.11e-36 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 32989 XM_029343199.2 422 33 75 117 96 NA NA NA NA NA NA 32990 XM_029343211.2 4037 2608 2302 3783 3917 Q9JLR1 0 Protein transport protein Sec61 subunit alpha isoform 2 (Sec61 alpha-2) Mus musculus (Mouse) post-translational protein targeting to membrane, translocation [GO:0031204]; SRP-dependent cotranslational protein targeting to membrane, translocation [GO:0006616] GO:0005048; GO:0005784; GO:0006616; GO:0008320; GO:0031204; GO:0043022 32991 XM_029329447.2 8485 6321 3726 8467 7276 Q7T0T9 1.01e-163 Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase); Lysophospholipase (EC 3.1.1.5)] Xenopus laevis (African clawed frog) phospholipid catabolic process [GO:0009395] GO:0004622; GO:0004623; GO:0005509; GO:0009395; GO:0031410; GO:0102545 32992 XR_006397967.1 2084 1560 1277 753 1192 NA NA NA NA NA NA 32993 XM_044319477.1 249 172 120 268 95 Q8TF32 2.86e-67 Zinc finger protein 431 Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355] GO:0000122; GO:0000978; GO:0000981; GO:0003682; GO:0005634; GO:0006355; GO:0030154; GO:0043433; GO:0046872 32994 XM_044319477.1 249 172 120 268 95 Q8TF32 2.09e-64 Zinc finger protein 431 Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355] GO:0000122; GO:0000978; GO:0000981; GO:0003682; GO:0005634; GO:0006355; GO:0030154; GO:0043433; GO:0046872 32995 XM_044319477.1 249 172 120 268 95 Q8TF32 3.45e-63 Zinc finger protein 431 Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355] GO:0000122; GO:0000978; GO:0000981; GO:0003682; GO:0005634; GO:0006355; GO:0030154; GO:0043433; GO:0046872 32996 XM_044319477.1 249 172 120 268 95 Q8TF32 3.59e-61 Zinc finger protein 431 Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355] GO:0000122; GO:0000978; GO:0000981; GO:0003682; GO:0005634; GO:0006355; GO:0030154; GO:0043433; GO:0046872 32997 XM_044319477.1 249 172 120 268 95 Q8TF32 4.46e-56 Zinc finger protein 431 Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355] GO:0000122; GO:0000978; GO:0000981; GO:0003682; GO:0005634; GO:0006355; GO:0030154; GO:0043433; GO:0046872 32998 XM_044319477.1 249 172 120 268 95 Q8TF32 7.25e-50 Zinc finger protein 431 Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355] GO:0000122; GO:0000978; GO:0000981; GO:0003682; GO:0005634; GO:0006355; GO:0030154; GO:0043433; GO:0046872 32999 XM_044319477.1 249 172 120 268 95 Q8TF32 3.12e-40 Zinc finger protein 431 Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355] GO:0000122; GO:0000978; GO:0000981; GO:0003682; GO:0005634; GO:0006355; GO:0030154; GO:0043433; GO:0046872 33000 XM_044319477.1 249 172 120 268 95 Q8TF32 4.82e-35 Zinc finger protein 431 Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355] GO:0000122; GO:0000978; GO:0000981; GO:0003682; GO:0005634; GO:0006355; GO:0030154; GO:0043433; GO:0046872 33001 XM_044319477.1 249 172 120 268 95 Q8TF32 7.81e-29 Zinc finger protein 431 Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355] GO:0000122; GO:0000978; GO:0000981; GO:0003682; GO:0005634; GO:0006355; GO:0030154; GO:0043433; GO:0046872 33002 XM_029343070.2 8 56 25 20 11 P18870 4.5e-33 Transcription factor Jun (Proto-oncogene c-Jun) (Transcription factor AP-1 subunit Jun) Gallus gallus (Chicken) positive regulation by host of viral transcription [GO:0043923]; positive regulation of cell growth [GO:0030307]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000976; GO:0000978; GO:0000981; GO:0005634; GO:0005667; GO:0006357; GO:0030307; GO:0042127; GO:0043923; GO:0045944; GO:0051726 33003 XR_003824579.2 197 200 24 140 115 NA NA NA NA NA NA 33004 XM_044308548.1 1 0 0 0 6 NA NA NA NA NA NA 33005 XM_029346919.2 1685 979 862 1645 2087 Q92503 0 SEC14-like protein 1 Homo sapiens (Human) choline transport [GO:0015871]; innate immune response [GO:0045087]; negative regulation of RIG-I signaling pathway [GO:0039536] GO:0005654; GO:0005737; GO:0005794; GO:0005829; GO:0015871; GO:0039536; GO:0039552; GO:0045087 33006 XM_044314050.1 320 299 128 226 98 Q6AZN8 9.11e-94 Zinc transporter 6-A (ZnT-6-A) (Solute carrier family 30 member 6-A) Xenopus laevis (African clawed frog) zinc ion import into Golgi lumen [GO:1904257] GO:0008324; GO:0032588; GO:1904257 33007 XM_029342028.2 14 16 6 36 12 P11617 4.26e-21 Adenosine receptor A2a Canis lupus familiaris (Dog) (Canis familiaris) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; apoptotic signaling pathway [GO:0097190]; eating behavior [GO:0042755]; G protein-coupled adenosine receptor signaling pathway [GO:0001973]; G protein-coupled receptor signaling pathway [GO:0007186]; inhibitory postsynaptic potential [GO:0060080]; locomotory behavior [GO:0007626]; negative regulation of alpha-beta T cell activation [GO:0046636]; negative regulation of inflammatory response [GO:0050728]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; response to amphetamine [GO:0001975]; response to inorganic substance [GO:0010035]; response to purine-containing compound [GO:0014074]; synaptic transmission, dopaminergic [GO:0001963] GO:0001609; GO:0001963; GO:0001973; GO:0001975; GO:0004930; GO:0005886; GO:0007186; GO:0007189; GO:0007626; GO:0008289; GO:0010035; GO:0014074; GO:0019899; GO:0032230; GO:0042755; GO:0042802; GO:0046636; GO:0050728; GO:0060080; GO:0097190; GO:0098794; GO:2001235 33008 XM_044311444.1 37 1 4 0 0 NA NA NA NA NA NA 33009 XM_029350184.2 996 858 668 1014 728 Q5RAK8 4.13e-47 Circadian locomoter output cycles protein kaput (EC 2.3.1.48) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cellular response to DNA damage stimulus [GO:0006974]; circadian regulation of gene expression [GO:0032922]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of glucocorticoid receptor signaling pathway [GO:2000323]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein acetylation [GO:0006473]; regulation of circadian rhythm [GO:0042752]; regulation of DNA-templated transcription [GO:0006355]; regulation of hair cycle [GO:0042634]; regulation of insulin secretion [GO:0050796]; regulation of type B pancreatic cell development [GO:2000074]; response to redox state [GO:0051775]; spermatogenesis [GO:0007283] GO:0000978; GO:0003677; GO:0003700; GO:0004402; GO:0005634; GO:0005667; GO:0005829; GO:0006355; GO:0006473; GO:0006974; GO:0007283; GO:0031490; GO:0032922; GO:0033391; GO:0042634; GO:0042752; GO:0043161; GO:0043565; GO:0045892; GO:0045893; GO:0045944; GO:0046983; GO:0050796; GO:0051092; GO:0051775; GO:0070888; GO:2000074; GO:2000323 33010 XM_044307412.1 298 695 354 2263 261 Q95P04 1.34e-160 GFP-like non-fluorescent chromoprotein (gtCP) Goniopora tenuidens (Anemone coral) (Rhodaraea tenuidens) bioluminescence [GO:0008218] GO:0008218 33011 XM_029333925.2 146 64 52 263 236 NA NA NA NA NA NA 33012 XM_029334546.2 45 17 56 18 74 NA NA NA NA NA NA 33013 XR_006393355.1 78 21 0 5 56 Q62384 1.76e-157 Zinc finger protein ZPR1 (Zinc finger protein 259) Mus musculus (Mouse) apoptotic process involved in development [GO:1902742]; axon development [GO:0061564]; Cajal body organization [GO:0030576]; cell population proliferation [GO:0008283]; cellular response to epidermal growth factor stimulus [GO:0071364]; DNA endoreduplication [GO:0042023]; inner cell mass cell proliferation [GO:0001833]; microtubule cytoskeleton organization [GO:0000226]; mRNA processing [GO:0006397]; negative regulation of motor neuron apoptotic process [GO:2000672]; positive regulation of cell cycle [GO:0045787]; positive regulation of gene expression [GO:0010628]; positive regulation of growth [GO:0045927]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of RNA splicing [GO:0033120]; positive regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0071931]; pre-mRNA catabolic process [GO:1990261]; regulation of myelination [GO:0031641]; RNA splicing [GO:0008380]; spinal cord development [GO:0021510]; trophectodermal cell proliferation [GO:0001834] GO:0000226; GO:0001833; GO:0001834; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0006397; GO:0008270; GO:0008283; GO:0008380; GO:0010628; GO:0015030; GO:0021510; GO:0030424; GO:0030426; GO:0030576; GO:0030971; GO:0031369; GO:0031641; GO:0033120; GO:0042023; GO:0042307; GO:0043025; GO:0043204; GO:0045787; GO:0045927; GO:0048471; GO:0061564; GO:0071364; GO:0071931; GO:0097504; GO:1902742; GO:1990261; GO:2000672 33014 XM_029331877.2 595 1233 345 746 746 NA NA NA NA NA NA 33015 XR_006392473.1 57 604 326 200 73 NA NA NA NA NA NA 33016 XM_029339024.2 10571 9649 5418 10274 9869 P63018 0 Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) Rattus norvegicus (Rat) aging [GO:0007568]; ATP metabolic process [GO:0046034]; axo-dendritic transport [GO:0008088]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; cerebellum development [GO:0021549]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein folding [GO:0061077]; clathrin coat disassembly [GO:0072318]; estrous cycle [GO:0044849]; forebrain development [GO:0030900]; G1/S transition of mitotic cell cycle [GO:0000082]; kidney development [GO:0001822]; late endosomal microautophagy [GO:0061738]; maintenance of postsynaptic specialization structure [GO:0098880]; modulation by host of viral process [GO:0044788]; mRNA processing [GO:0006397]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of supramolecular fiber organization [GO:1902904]; positive regulation by host of viral genome replication [GO:0044829]; positive regulation of catalytic activity [GO:0043085]; positive regulation of gene expression [GO:0010628]; positive regulation of lysosomal membrane permeability [GO:0097214]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein refolding [GO:1904592]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein autophosphorylation [GO:0046777]; protein folding [GO:0006457]; protein import into nucleus [GO:0006606]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; protein transmembrane import into intracellular organelle [GO:0044743]; protein-containing complex disassembly [GO:0032984]; regulation of cell cycle [GO:0051726]; regulation of postsynapse organization [GO:0099175]; regulation of protein complex stability [GO:0061635]; regulation of protein stability [GO:0031647]; response to activity [GO:0014823]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to nickel cation [GO:0010045]; response to odorant [GO:1990834]; response to progesterone [GO:0032570]; response to starvation [GO:0042594]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; sensory perception of smell [GO:0007608]; skeletal muscle tissue development [GO:0007519]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192] GO:0000082; GO:0000974; GO:0001664; GO:0001786; GO:0001822; GO:0001916; GO:0001917; GO:0003723; GO:0005102; GO:0005524; GO:0005634; GO:0005681; GO:0005730; GO:0005737; GO:0005764; GO:0005765; GO:0005770; GO:0005776; GO:0005829; GO:0005874; GO:0005882; GO:0005886; GO:0006397; GO:0006457; GO:0006606; GO:0007519; GO:0007568; GO:0007608; GO:0008021; GO:0008088; GO:0008380; GO:0009408; GO:0009410; GO:0009986; GO:0010045; GO:0010628; GO:0010667; GO:0014069; GO:0014823; GO:0016191; GO:0016192; GO:0016887; GO:0019899; GO:0021549; GO:0030424; GO:0030425; GO:0030674; GO:0030900; GO:0031072; GO:0031625; GO:0031647; GO:0031686; GO:0032279; GO:0032355; GO:0032570; GO:0032984; GO:0032991; GO:0034605; GO:0034620; GO:0042026; GO:0042277; GO:0042470; GO:0042594; GO:0043005; GO:0043025; GO:0043085; GO:0043195; GO:0043197; GO:0043198; GO:0043202; GO:0043204; GO:0043531; GO:0044183; GO:0044309; GO:0044743; GO:0044788; GO:0044829; GO:0044849; GO:0045121; GO:0045471; GO:0045862; GO:0045892; GO:0046034; GO:0046777; GO:0048026; GO:0048471; GO:0050766; GO:0051082; GO:0051085; GO:0051087; GO:0051726; GO:0051787; GO:0055131; GO:0061077; GO:0061635; GO:0061684; GO:0061738; GO:0061740; GO:0070062; GO:0071276; GO:0072318; GO:0097214; GO:0098684; GO:0098690; GO:0098793; GO:0098794; GO:0098880; GO:0098978; GO:0099175; GO:0099523; GO:0099524; GO:0099634; GO:0101031; GO:0140545; GO:0140662; GO:1902904; GO:1903206; GO:1904592; GO:1904593; GO:1904764; GO:1990124; GO:1990832; GO:1990833; GO:1990834; GO:1990836; GO:1990904 33017 XM_044315856.1 12 12 0 2 55 B3EWZ6 5.43e-28 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 33018 XM_044315856.1 12 12 0 2 55 B3EWZ6 8.62e-24 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 33019 XM_044315856.1 12 12 0 2 55 B3EWZ6 8.84e-23 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 33020 XM_044315856.1 12 12 0 2 55 B3EWZ6 1.48e-22 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 33021 XM_044315856.1 12 12 0 2 55 B3EWZ6 4.71e-22 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 33022 XM_044315856.1 12 12 0 2 55 B3EWZ6 5.24e-22 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 33023 XM_044315856.1 12 12 0 2 55 B3EWZ6 7.81e-22 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 33024 XM_044315856.1 12 12 0 2 55 B3EWZ6 3.99e-21 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 33025 XM_044315856.1 12 12 0 2 55 B3EWZ6 8.48e-21 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 33026 XM_044324867.1 4925 3673 3269 3760 1792 NA NA NA NA NA NA 33027 XM_044328298.1 198 70 0 7 197 Q6NVC5 0 Mitochondrial Rho GTPase 1-A (MIRO-1-A) (EC 3.6.5.-) (Ras homolog gene family member T1-A) Danio rerio (Zebrafish) (Brachydanio rerio) cellular homeostasis [GO:0019725]; mitochondrial outer membrane permeabilization [GO:0097345]; mitochondrion organization [GO:0007005]; mitochondrion transport along microtubule [GO:0047497]; regulation of mitochondrion organization [GO:0010821]; small GTPase mediated signal transduction [GO:0007264] GO:0003924; GO:0005509; GO:0005525; GO:0005739; GO:0005741; GO:0007005; GO:0007264; GO:0010821; GO:0019725; GO:0047497; GO:0097345 33028 XM_044322096.1 6 0 10 0 19 D3YXG0 1.87e-95 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 33029 XM_044322096.1 6 0 10 0 19 D3YXG0 1.31e-92 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 33030 XM_044322096.1 6 0 10 0 19 D3YXG0 5.25e-88 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 33031 XM_044322096.1 6 0 10 0 19 D3YXG0 6.7e-76 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 33032 XM_044322096.1 6 0 10 0 19 D3YXG0 3.9e-67 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 33033 XM_029335927.2 480 369 241 399 444 Q5U4T9 2.04e-91 Lysophospholipid acyltransferase 7 (LPLAT 7) (EC 2.3.1.-) (Leukocyte receptor cluster member 4) (Membrane-bound O-acyltransferase domain-containing protein 7) (O-acyltransferase domain-containing protein 7) Xenopus laevis (African clawed frog) phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylinositol acyl-chain remodeling [GO:0036149]; phosphatidylinositol biosynthetic process [GO:0006661]; regulation of triglyceride metabolic process [GO:0090207] GO:0005789; GO:0006661; GO:0008374; GO:0036149; GO:0036151; GO:0090207 33034 XM_029335652.2 64 123 0 94 103 F6QEU4 6.77e-52 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 33035 XR_006396711.1 4 69 59 113 107 NA NA NA NA NA NA 33036 XM_044328245.1 60 58 35 58 85 Q49SH1 5.22e-99 Sodium/potassium/calcium exchanger 5 (Na(+)/K(+)/Ca(2+)-exchange protein 5) (Protein golden) (Solute carrier family 24 member 5) Danio rerio (Zebrafish) (Brachydanio rerio) calcium ion transport [GO:0006816]; potassium ion transport [GO:0006813]; response to stimulus [GO:0050896]; sodium ion transport [GO:0006814] GO:0005794; GO:0006813; GO:0006814; GO:0006816; GO:0015293; GO:0015297; GO:0016020; GO:0042470; GO:0050896 33037 XM_029349685.2 4520 2714 2650 4659 5366 Q14151 1.79e-32 Scaffold attachment factor B2 (SAF-B2) Homo sapiens (Human) regulation of androgen receptor signaling pathway [GO:0060765]; regulation of mRNA processing [GO:0050684]; regulation of transcription by RNA polymerase II [GO:0006357]; Sertoli cell differentiation [GO:0060008] GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006357; GO:0016604; GO:0042802; GO:0043231; GO:0043565; GO:0050684; GO:0060008; GO:0060765; GO:0070062 33038 XM_029333426.2 6578 8046 2912 6239 4612 Q6PAB3 6.77e-151 Malate dehydrogenase, cytoplasmic (EC 1.1.1.37) (Cytosolic malate dehydrogenase) Xenopus laevis (African clawed frog) malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099] GO:0005737; GO:0006099; GO:0006108; GO:0030060 33039 XM_029352228.2 148 0 99 144 0 NA NA NA NA NA NA 33040 XM_029347558.2 167 164 115 194 93 Q8K4H1 8.65e-66 Kynurenine formamidase (KFA) (KFase) (EC 3.5.1.9) (Arylformamidase) (N-formylkynurenine formamidase) (FKF) Mus musculus (Mouse) 'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; tryptophan catabolic process to kynurenine [GO:0019441] GO:0004061; GO:0005634; GO:0005737; GO:0005829; GO:0019441; GO:0034354 33041 XR_006395927.1 0 0 0 9 0 NA NA NA NA NA NA 33042 XM_029333662.2 153 61 38 99 71 NA NA NA NA NA NA 33043 XM_044310201.1 82 61 34 0 2 NA NA NA NA NA NA 33044 XM_029332125.2 22 34 43 47 56 O15178 2.55e-118 T-box transcription factor T (Brachyury protein) (Protein T) Homo sapiens (Human) anterior/posterior axis specification, embryo [GO:0008595]; cardiac muscle cell myoblast differentiation [GO:0060379]; cell fate specification [GO:0001708]; heart morphogenesis [GO:0003007]; mesoderm development [GO:0007498]; mesoderm formation [GO:0001707]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; primitive streak formation [GO:0090009]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; somitogenesis [GO:0001756] GO:0000122; GO:0000785; GO:0000978; GO:0000981; GO:0001707; GO:0001708; GO:0001756; GO:0003007; GO:0003700; GO:0005634; GO:0005654; GO:0006357; GO:0007165; GO:0007498; GO:0008595; GO:0043433; GO:0045944; GO:0060379; GO:0061629; GO:0090009; GO:1990837 33045 XM_044309606.1 66 198 63 34 53 NA NA NA NA NA NA 33046 XM_044308452.1 37 94 85 165 148 NA NA NA NA NA NA 33047 XM_044321340.1 0 0 0 0 35 Q13416 5.63e-113 Origin recognition complex subunit 2 Homo sapiens (Human) DNA replication initiation [GO:0006270]; negative regulation of transcription by RNA polymerase II [GO:0000122] GO:0000122; GO:0000781; GO:0000792; GO:0000808; GO:0000939; GO:0003688; GO:0005634; GO:0005654; GO:0005664; GO:0005813; GO:0006270; GO:0016020 33048 XM_029344186.2 2004 1711 745 1903 2638 O46640 8.54e-53 Amine sulfotransferase (EC 2.8.2.3) (AST-RB1) (Sulfotransferase 3A1) (ST3A1) Oryctolagus cuniculus (Rabbit) NA GO:0005737; GO:0047685 33049 XM_044313017.1 0 0 0 58 0 P22300 5.17e-39 Gamma-aminobutyric acid receptor subunit gamma-2 (GABA(A) receptor subunit gamma-2) Bos taurus (Bovine) cellular response to histamine [GO:0071420]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid signaling pathway [GO:0007214]; inhibitory synapse assembly [GO:1904862] GO:0004890; GO:0005230; GO:0005254; GO:0005886; GO:0007214; GO:0030425; GO:0030659; GO:0034707; GO:0045211; GO:0071420; GO:1902476; GO:1902711; GO:1904862 33050 XR_006391671.1 151 25 98 70 356 NA NA NA NA NA NA 33051 XM_044314253.1 10 20 5 1 23 Q96AY4 1.33e-62 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33052 XM_044314253.1 10 20 5 1 23 Q96AY4 2.35e-61 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33053 XM_044314253.1 10 20 5 1 23 Q96AY4 9.97e-61 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33054 XM_044314253.1 10 20 5 1 23 Q96AY4 7.63e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33055 XM_044314253.1 10 20 5 1 23 Q96AY4 6.43e-55 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33056 XM_044314253.1 10 20 5 1 23 Q96AY4 6.39e-50 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33057 XM_044314253.1 10 20 5 1 23 Q96AY4 5.2e-47 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33058 XM_044314253.1 10 20 5 1 23 Q96AY4 9.23e-45 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33059 XM_044314253.1 10 20 5 1 23 Q96AY4 5.11e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33060 XM_044314253.1 10 20 5 1 23 Q96AY4 6.56e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33061 XM_044314253.1 10 20 5 1 23 Q96AY4 1.58e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33062 XM_044314253.1 10 20 5 1 23 Q96AY4 6.35e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33063 XM_044314253.1 10 20 5 1 23 Q96AY4 6.64e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33064 XM_044311609.1 17 0 0 0 0 P0CT40 1.79e-86 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 33065 XM_029354747.2 1772 1622 974 379 0 Q9EQC4 1.88e-63 Elongation of very long chain fatty acids protein 4 (EC 2.3.1.199) (3-keto acyl-CoA synthase Elovl4) (ELOVL fatty acid elongase 4) (ELOVL FA elongase 4) (Very long chain 3-ketoacyl-CoA synthase 4) (Very long chain 3-oxoacyl-CoA synthase 4) Mus musculus (Mouse) fatty acid elongation, monounsaturated fatty acid [GO:0034625]; fatty acid elongation, polyunsaturated fatty acid [GO:0034626]; fatty acid elongation, saturated fatty acid [GO:0019367]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; sphingolipid biosynthetic process [GO:0030148]; unsaturated fatty acid biosynthetic process [GO:0006636]; very long-chain fatty acid biosynthetic process [GO:0042761] GO:0005783; GO:0005789; GO:0006636; GO:0009922; GO:0019367; GO:0030148; GO:0034625; GO:0034626; GO:0035338; GO:0042761; GO:0102756 33066 XM_029327527.2 1237 855 262 2287 1152 Q19269 3.26e-46 Zinc metalloproteinase nas-14 (EC 3.4.24.-) (Nematode astacin 14) Caenorhabditis elegans proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0006508; GO:0008270 33067 XM_029329386.2 11 0 51 22 34 P46023 2.42e-113 G-protein coupled receptor GRL101 Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004930; GO:0005886 33068 XM_029333193.2 0 28 0 38 0 Q16281 1.91e-127 Cyclic nucleotide-gated cation channel alpha-3 (Cone photoreceptor cGMP-gated channel subunit alpha) (Cyclic nucleotide-gated channel alpha-3) (CNG channel alpha-3) (CNG-3) (CNG3) Homo sapiens (Human) cation transmembrane transport [GO:0098655]; cation transport [GO:0006812]; inorganic cation import across plasma membrane [GO:0098659]; response to cAMP [GO:0051591]; response to corticosteroid [GO:0031960]; response to magnesium ion [GO:0032026]; signal transduction [GO:0007165]; visual perception [GO:0007601] GO:0005222; GO:0005223; GO:0005737; GO:0005886; GO:0006812; GO:0007165; GO:0007601; GO:0008022; GO:0015276; GO:0017071; GO:0030425; GO:0030553; GO:0031960; GO:0032026; GO:0043194; GO:0043204; GO:0044877; GO:0051591; GO:0097386; GO:0098655; GO:0098659; GO:1902495 33069 XM_044311522.1 44 40 190 201 193 Q9VBW3 1.72e-77 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 33070 XM_029355969.2 771 311 332 470 660 Q6GQB9 0 ER degradation-enhancing alpha-mannosidase-like protein 3 (EC 3.2.1.113) (Alpha-1,2-mannosidase EDEM3) Xenopus laevis (African clawed frog) carbohydrate metabolic process [GO:0005975]; endoplasmic reticulum mannose trimming [GO:1904380]; mannose trimming involved in glycoprotein ERAD pathway [GO:1904382]; protein glycosylation [GO:0006486]; response to unfolded protein [GO:0006986] GO:0004571; GO:0005509; GO:0005788; GO:0005975; GO:0006486; GO:0006986; GO:0016020; GO:0044322; GO:1904380; GO:1904382 33071 XM_044317522.1 38 11 12 41 0 C3VPR6 2.13e-28 Protein NLRC5 Mus musculus (Mouse) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of type II interferon-mediated signaling pathway [GO:0060335]; regulation of kinase activity [GO:0043549]; response to bacterium [GO:0009617] GO:0000978; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0009617; GO:0032088; GO:0035556; GO:0043549; GO:0045087; GO:0045345; GO:0045944; GO:0051607; GO:0060335; GO:0060339; GO:0060340 33072 XM_044328330.1 124 1212 828 554 914 NA NA NA NA NA NA 33073 XM_029336750.2 56 211 143 119 126 NA NA NA NA NA NA 33074 XM_044311202.1 3518 1537 1081 3565 1527 NA NA NA NA NA NA 33075 XM_044328940.1 248 47 29 76 78 Q9H857 1.17e-141 5'-nucleotidase domain-containing protein 2 (EC 3.1.3.-) Homo sapiens (Human) NA GO:0008253; GO:0046872 33076 XM_044312763.1 0 7 2 0 0 Q5RCP8 4.93e-58 Histone H2B type 2-E (H2B-clustered histone 21) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) defense response to bacterium [GO:0042742] GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0042742; GO:0046982 33077 XM_029338835.2 83 89 161 261 177 NA NA NA NA NA NA 33078 XM_044326614.1 20 0 6 0 9 NA NA NA NA NA NA 33079 XM_044307559.1 12626 13896 5384 8133 6429 NA NA NA NA NA NA 33080 XM_044319115.1 114 45 59 60 88 NA NA NA NA NA NA 33081 XM_029324462.2 414 370 237 239 474 NA NA NA NA NA NA 33082 XM_029356979.2 0 0 12 0 8 Q6QNK2 1.24e-71 Adhesion G-protein coupled receptor D1 (G-protein coupled receptor 133) (G-protein coupled receptor PGR25) Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0005654; GO:0005886; GO:0007166; GO:0007186; GO:0007189; GO:0016020 33083 XM_044309535.1 1 0 1 5 6 NA NA NA NA NA NA 33084 XM_029351376.2 303 256 146 127 145 NA NA NA NA NA NA 33085 XM_044323051.1 0 0 11 10 53 Q08DY9 2.81e-40 Caspase-3 (CASP-3) (EC 3.4.22.56) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12] Bos taurus (Bovine) positive regulation of amyloid-beta formation [GO:1902004]; proteolysis [GO:0006508]; regulation of protein stability [GO:0031647] GO:0004175; GO:0005737; GO:0006508; GO:0031647; GO:0097153; GO:0097199; GO:0097200; GO:1902004 33086 XM_029352696.2 2022 1541 874 1171 889 Q9W2H1 2.19e-43 TM2 domain-containing protein CG10795 Drosophila melanogaster (Fruit fly) positive regulation of Notch signaling pathway [GO:0045747] GO:0005886; GO:0045747 33087 XM_044318931.1 640 278 178 116 746 Q9BUZ4 7.61e-55 TNF receptor-associated factor 4 (EC 2.3.2.27) (Cysteine-rich domain associated with RING and Traf domains protein 1) (Metastatic lymph node gene 62 protein) (MLN 62) (RING finger protein 83) Homo sapiens (Human) activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; innate immune response [GO:0045087]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein kinase activity [GO:0045860]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; respiratory gaseous exchange by respiratory system [GO:0007585]; respiratory tube development [GO:0030323] GO:0001650; GO:0005164; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0005923; GO:0006915; GO:0007250; GO:0007585; GO:0008270; GO:0016740; GO:0019901; GO:0030323; GO:0031625; GO:0031996; GO:0042802; GO:0042981; GO:0043122; GO:0043161; GO:0045087; GO:0045860; GO:0046330; GO:0048471; GO:0050699 33088 XM_044319168.1 74 0 8 0 22 O88917 5.3e-48 Adhesion G protein-coupled receptor L1 (Calcium-independent alpha-latrotoxin receptor 1) (CIRL-1) (Latrophilin-1) Rattus norvegicus (Rat) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; brain development [GO:0007420]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell surface receptor signaling pathway [GO:0007166]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synapse maturation [GO:0090129] GO:0004930; GO:0005886; GO:0007157; GO:0007166; GO:0007189; GO:0007420; GO:0014069; GO:0015643; GO:0016524; GO:0030246; GO:0030424; GO:0030426; GO:0035584; GO:0042734; GO:0043005; GO:0045202; GO:0050839; GO:0051965; GO:0090129; GO:0098978 33089 XM_029331530.2 103 73 118 134 152 Q58D06 8.44e-84 WD repeat-containing protein 74 Bos taurus (Bovine) blastocyst formation [GO:0001825]; ribosomal large subunit biogenesis [GO:0042273]; RNA metabolic process [GO:0016070]; rRNA processing [GO:0006364] GO:0000176; GO:0001825; GO:0005634; GO:0005654; GO:0005730; GO:0006364; GO:0016070; GO:0030687; GO:0042273 33090 XR_006392284.1 9 37 15 29 13 NA NA NA NA NA NA 33091 XM_029337127.2 309 96 21 184 124 NA NA NA NA NA NA 33092 XM_044318079.1 11 105 34 0 30 NA NA NA NA NA NA 33093 XM_029354489.2 10 0 5 3 22 O42412 2.6e-53 Thyroxine 5-deiodinase (EC 1.21.99.3) (5DIII) (DIOIII) (Type 3 DI) (Type III iodothyronine deiodinase) Gallus gallus (Chicken) hormone biosynthetic process [GO:0042446]; thyroid hormone metabolic process [GO:0042403] GO:0004800; GO:0005886; GO:0010008; GO:0033798; GO:0042403; GO:0042446 33094 XM_044315493.1 46 9 6 13 26 NA NA NA NA NA NA 33095 XM_029337816.2 0 0 0 0 15 NA NA NA NA NA NA 33096 XM_044328266.1 109 206 175 73 172 Q7JQD3 3.52e-34 Gelsolin-like protein 1 (Actin-modulator) (EWAM) (EWAM-P1) Lumbricus terrestris (Common earthworm) actin filament capping [GO:0051693]; actin filament fragmentation [GO:0030043]; actin filament polymerization [GO:0030041]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010] GO:0003779; GO:0005509; GO:0005737; GO:0005856; GO:0030041; GO:0030043; GO:0045010; GO:0051014; GO:0051015; GO:0051693 33097 XM_029343669.2 886 982 281 870 24 NA NA NA NA NA NA 33098 XM_029339648.2 2172 1832 1350 2427 2476 Q9NWM3 2.6e-40 CUE domain-containing protein 1 Homo sapiens (Human) NA GO:0043130 33099 XR_006396924.1 67 6 19 10 42 O46640 3.63e-53 Amine sulfotransferase (EC 2.8.2.3) (AST-RB1) (Sulfotransferase 3A1) (ST3A1) Oryctolagus cuniculus (Rabbit) NA GO:0005737; GO:0047685 33100 XR_003826504.2 2 6 0 4 2 NA NA NA NA NA NA 33101 XR_006394789.1 296 205 235 252 435 NA NA NA NA NA NA 33102 XM_029340240.2 314 144 89 352 44 NA NA NA NA NA NA 33103 XM_029332482.2 4050 3192 1012 3388 1499 Q4R562 3.28e-153 Beta-arrestin-1 (Arrestin beta-1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) negative regulation of Notch signaling pathway [GO:0045746]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; protein transport [GO:0015031]; signal transduction [GO:0007165]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0001934; GO:0002092; GO:0005634; GO:0005905; GO:0006511; GO:0007165; GO:0015031; GO:0031143; GO:0031410; GO:0045746 33104 XM_029356078.2 28909 36354 17176 26507 23057 NA NA NA NA NA NA 33105 XM_029325067.2 11 0 0 5 10 NA NA NA NA NA NA 33106 XM_029345708.2 0 124 101 138 113 NA NA NA NA NA NA 33107 XM_044324445.1 159 42 106 0 420 NA NA NA NA NA NA 33108 XM_044327463.1 158 149 106 246 65 NA NA NA NA NA NA 33109 XM_044311496.1 0 4 14 16 0 NA NA NA NA NA NA 33110 XR_006394556.1 63 62 9 44 5 NA NA NA NA NA NA 33111 XM_044308348.1 302 265 231 224 307 B4E2M5 5.99e-23 Ankyrin repeat domain-containing protein 66 Homo sapiens (Human) NA NA 33112 XM_029348117.2 863 624 523 753 861 Q6P2T7 2.58e-42 UPF0462 protein C4orf33 homolog Danio rerio (Zebrafish) (Brachydanio rerio) NA NA 33113 XM_044327348.1 10 10 5 7 0 NA NA NA NA NA NA 33114 XM_029325278.2 665 634 448 542 316 NA NA NA NA NA NA 33115 XM_029356699.2 838 463 591 978 1144 Q8WUA4 4.58e-74 General transcription factor 3C polypeptide 2 (TF3C-beta) (Transcription factor IIIC 110 kDa subunit) (TFIIIC 110 kDa subunit) (TFIIIC110) (Transcription factor IIIC subunit beta) Homo sapiens (Human) 5S class rRNA transcription by RNA polymerase III [GO:0042791]; transcription by RNA polymerase III [GO:0006383]; tRNA transcription by RNA polymerase III [GO:0042797] GO:0000127; GO:0000995; GO:0005654; GO:0006383; GO:0042791; GO:0042797 33116 XM_029327011.2 0 0 0 0 24 Q5BKQ4 1.88e-60 Inactive pancreatic lipase-related protein 1 (PL-RP1) Mus musculus (Mouse) lipid metabolic process [GO:0006629] GO:0004806; GO:0005509; GO:0005615; GO:0006629; GO:0016298 33117 XM_029345852.2 4937 3567 1899 5071 2547 Q75N90 9.02e-83 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 33118 XM_029345852.2 4937 3567 1899 5071 2547 Q75N90 1.43e-71 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 33119 XM_029345852.2 4937 3567 1899 5071 2547 Q75N90 5.03e-69 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 33120 XM_029345852.2 4937 3567 1899 5071 2547 Q75N90 1.83e-67 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 33121 XM_029345852.2 4937 3567 1899 5071 2547 Q75N90 2.33e-67 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 33122 XM_029345852.2 4937 3567 1899 5071 2547 Q75N90 5.83e-67 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 33123 XM_029345852.2 4937 3567 1899 5071 2547 Q75N90 9.82e-67 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 33124 XM_029345852.2 4937 3567 1899 5071 2547 Q75N90 1.05e-66 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 33125 XM_029345852.2 4937 3567 1899 5071 2547 Q75N90 1.23e-65 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 33126 XM_029345852.2 4937 3567 1899 5071 2547 Q75N90 2.01e-65 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 33127 XM_029345852.2 4937 3567 1899 5071 2547 Q75N90 6.33e-63 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 33128 XM_029345852.2 4937 3567 1899 5071 2547 Q75N90 7.64e-62 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 33129 XM_029345852.2 4937 3567 1899 5071 2547 Q75N90 3.27e-61 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 33130 XM_029345852.2 4937 3567 1899 5071 2547 Q75N90 1.16e-57 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 33131 XM_029345852.2 4937 3567 1899 5071 2547 Q75N90 5.13e-48 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 33132 XM_044308717.1 0 0 6 0 0 NA NA NA NA NA NA 33133 XM_044311767.1 9 13 35 9 2 B8VIU6 5.08e-41 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 33134 XM_044324875.1 80 87 55 14 37 P79381 2.34e-123 Epoxide hydrolase 1 (EC 3.3.2.9) (Epoxide hydratase) (Microsomal epoxide hydrolase) (mEH) Sus scrofa (Pig) arachidonic acid metabolic process [GO:0019369]; aromatic compound catabolic process [GO:0019439]; epoxide metabolic process [GO:0097176]; response to toxic substance [GO:0009636] GO:0004301; GO:0005789; GO:0009636; GO:0019369; GO:0019439; GO:0033961; GO:0097176 33135 XM_044329242.1 212 19 139 69 155 NA NA NA NA NA NA 33136 XM_044320058.1 49 74 0 175 36 B8EIZ7 3.58e-169 NA NA NA NA 33137 XM_044307790.1 360 200 101 387 398 NA NA NA NA NA NA 33138 XM_044310445.1 259 62 83 229 418 Q9JMA7 1.98e-95 Cytochrome P450 3A41 (EC 1.14.14.1) Mus musculus (Mouse) alkaloid catabolic process [GO:0009822]; estrogen metabolic process [GO:0008210]; lipid hydroxylation [GO:0002933]; oxidative demethylation [GO:0070989]; regulation of gene expression [GO:0010468]; response to bacterium [GO:0009617]; retinoic acid metabolic process [GO:0042573]; steroid metabolic process [GO:0008202]; xenobiotic catabolic process [GO:0042178] GO:0002933; GO:0004497; GO:0005506; GO:0005789; GO:0008202; GO:0008210; GO:0008395; GO:0008401; GO:0009617; GO:0009822; GO:0010468; GO:0016491; GO:0020037; GO:0032451; GO:0042178; GO:0042573; GO:0043231; GO:0050649; GO:0070330; GO:0070989; GO:0101020 33139 XM_044310445.1 259 62 83 229 418 Q9JMA7 1.24e-89 Cytochrome P450 3A41 (EC 1.14.14.1) Mus musculus (Mouse) alkaloid catabolic process [GO:0009822]; estrogen metabolic process [GO:0008210]; lipid hydroxylation [GO:0002933]; oxidative demethylation [GO:0070989]; regulation of gene expression [GO:0010468]; response to bacterium [GO:0009617]; retinoic acid metabolic process [GO:0042573]; steroid metabolic process [GO:0008202]; xenobiotic catabolic process [GO:0042178] GO:0002933; GO:0004497; GO:0005506; GO:0005789; GO:0008202; GO:0008210; GO:0008395; GO:0008401; GO:0009617; GO:0009822; GO:0010468; GO:0016491; GO:0020037; GO:0032451; GO:0042178; GO:0042573; GO:0043231; GO:0050649; GO:0070330; GO:0070989; GO:0101020 33140 XM_044306959.1 11 11 9 23 11 NA NA NA NA NA NA 33141 XM_044312625.1 47 3 10 14 18 NA NA NA NA NA NA 33142 XR_006395913.1 131 17 51 34 0 NA NA NA NA NA NA 33143 XM_029336816.2 2329 663 962 2330 789 Q5VVW2 0 GTPase-activating Rap/Ran-GAP domain-like protein 3 Homo sapiens (Human) activation of GTPase activity [GO:0090630]; regulation of small GTPase mediated signal transduction [GO:0051056] GO:0005096; GO:0005737; GO:0051056; GO:0090630 33144 XM_044311909.1 0 18 16 16 4 NA NA NA NA NA NA 33145 XM_029332739.2 3049 3119 1204 4154 2283 Q0P483 2.07e-99 Mitochondrial coenzyme A transporter SLC25A42 (Solute carrier family 25 member 42) Danio rerio (Zebrafish) (Brachydanio rerio) ADP transport [GO:0015866]; AMP transport [GO:0080121]; ATP transport [GO:0015867]; coenzyme A transmembrane transport [GO:0035349]; mitochondrial coenzyme A transmembrane transport [GO:1990559]; mitochondrial membrane organization [GO:0007006] GO:0005347; GO:0005739; GO:0005743; GO:0007006; GO:0015217; GO:0015228; GO:0015866; GO:0015867; GO:0035349; GO:0043262; GO:0080121; GO:0080122; GO:1990559 33146 XM_029326771.2 934 849 348 1368 412 NA NA NA NA NA NA 33147 XM_044313892.1 8 0 0 1 2 NA NA NA NA NA NA 33148 XM_029353481.2 0 34 0 138 393 NA NA NA NA NA NA 33149 XM_029331488.2 290 170 137 343 198 NA NA NA NA NA NA 33150 XM_044323894.1 223 27 452 500 97 NA NA NA NA NA NA 33151 XM_044307922.1 0 0 6 31 14 NA NA NA NA NA NA 33152 XM_044318200.1 0 7 0 1 15 NA NA NA NA NA NA 33153 XM_029324144.2 805 435 589 992 1331 Q803S3 5.68e-123 Protein MEMO1 (Mediator of ErbB2-driven cell motility 1) (Memo-1) Danio rerio (Zebrafish) (Brachydanio rerio) NA NA 33154 XM_044306977.1 227968 209854 131257 237113 239742 NA NA NA NA NA NA 33155 XM_029347712.2 296 223 179 315 443 Q9JI78 6.77e-174 Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase (PNGase) (mPNGase) (EC 3.5.1.52) (N-glycanase 1) (Peptide:N-glycanase) Mus musculus (Mouse) ER-associated misfolded protein catabolic process [GO:0071712]; glycoprotein catabolic process [GO:0006516]; protein deglycosylation [GO:0006517]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515] GO:0000224; GO:0005634; GO:0005737; GO:0005829; GO:0006515; GO:0006516; GO:0006517; GO:0046872; GO:0062023; GO:0071712 33156 XM_029354143.2 1250 1062 746 867 1141 A7SJ66 3.78e-73 UPF0587 protein v1g245604 Nematostella vectensis (Starlet sea anemone) NA GO:0008270 33157 XM_044323453.1 17 80 37 29 26 NA NA NA NA NA NA 33158 XM_044308829.1 0 0 0 0 34 NA NA NA NA NA NA 33159 XM_029349425.2 1087 1010 854 1637 1334 Q9ERQ8 1.23e-50 Carbonic anhydrase 7 (EC 4.2.1.1) (Carbonate dehydratase VII) (Carbonic anhydrase VII) (CA-VII) Mus musculus (Mouse) neuron cellular homeostasis [GO:0070050]; one-carbon metabolic process [GO:0006730]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453] GO:0004089; GO:0005829; GO:0006730; GO:0008270; GO:0016836; GO:0032230; GO:0032849; GO:0051453; GO:0070050; GO:2001225 33160 XM_044315049.1 3 19 21 24 23 NA NA NA NA NA NA 33161 XM_044322816.1 0 1 0 0 85 NA NA NA NA NA NA 33162 XM_029356630.2 6543 4594 3598 6934 6663 Q91VC9 2.56e-86 Growth hormone-inducible transmembrane protein (Mitochondrial morphology and cristae structure 1) (MICS1) Mus musculus (Mouse) apoptotic process [GO:0006915]; inner mitochondrial membrane organization [GO:0007007]; negative regulation of release of cytochrome c from mitochondria [GO:0090201] GO:0005739; GO:0005743; GO:0006915; GO:0007007; GO:0016020; GO:0090201 33163 XM_029338817.2 15846 21495 9918 15591 10513 P62282 8.54e-77 40S ribosomal protein S11 Rattus norvegicus (Rat) osteoblast differentiation [GO:0001649]; translation [GO:0006412] GO:0001649; GO:0003735; GO:0006412; GO:0016020; GO:0019843; GO:0022626; GO:0022627; GO:0045202 33164 XM_044310385.1 110 11 4 5 78 NA NA NA NA NA NA 33165 XM_044322978.1 85 20 53 54 136 NA NA NA NA NA NA 33166 XM_029327244.2 122 65 59 135 121 NA NA NA NA NA NA 33167 XM_029333449.2 52 25 44 11 159 NA NA NA NA NA NA 33168 XM_029330274.2 106 0 0 21 27 O42574 8.48e-36 Beta-1 adrenergic receptor (Beta-1 adrenoreceptor) (Beta-1 adrenoceptor) (x-BETA1AR) Xenopus laevis (African clawed frog) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; positive regulation of GTPase activity [GO:0043547]; positive regulation of heart contraction [GO:0045823] GO:0004940; GO:0005085; GO:0005769; GO:0005886; GO:0043547; GO:0045823; GO:0071880 33169 XM_044318666.1 0 0 0 198 27 O75899 9.59e-72 Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51) (HG20) Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway [GO:0007186]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; neuron-glial cell signaling [GO:0150099]; synaptic transmission, GABAergic [GO:0051932] GO:0004888; GO:0004965; GO:0005737; GO:0005886; GO:0007186; GO:0007193; GO:0007194; GO:0007214; GO:0007268; GO:0038039; GO:0043005; GO:0045211; GO:0046982; GO:0051932; GO:0150099; GO:1902710; GO:1902712 33170 XM_029328934.2 3150 2612 2077 3073 2528 P98081 3.83e-32 Protein disabled Drosophila melanogaster (Fruit fly) cellularization [GO:0007349]; clathrin-dependent endocytosis [GO:0072583]; compound eye photoreceptor development [GO:0042051]; dorsal closure [GO:0007391]; motor neuron axon guidance [GO:0008045]; mushroom body development [GO:0016319]; positive regulation of sevenless signaling pathway [GO:0045874]; receptor-mediated endocytosis [GO:0006898]; synaptic vesicle endocytosis [GO:0048488] GO:0005118; GO:0005737; GO:0005829; GO:0006898; GO:0007349; GO:0007391; GO:0008045; GO:0016319; GO:0017124; GO:0030424; GO:0035591; GO:0042051; GO:0045874; GO:0048488; GO:0072583; GO:0098793 33171 XR_006398192.1 3 5 0 0 7 NA NA NA NA NA NA 33172 XM_029339786.2 0 0 91 0 0 NA NA NA NA NA NA 33173 XM_044310553.1 20 0 6 0 0 NA NA NA NA NA NA 33174 XM_029327255.2 66 33 35 226 245 B0S5Y3 5.45e-51 Solute carrier family 52, riboflavin transporter, member 3-A (Riboflavin transporter 2-A) (RFT2-A) Danio rerio (Zebrafish) (Brachydanio rerio) riboflavin transport [GO:0032218] GO:0005886; GO:0032217; GO:0032218 33175 XM_044320173.1 0 31 125 0 309 Q5DTN8 9.24e-50 Janus kinase and microtubule-interacting protein 3 (Neuroendocrine long coiled-coil protein 2) Mus musculus (Mouse) NA GO:0005794; GO:0008017; GO:0019900 33176 XM_044318766.1 11 13 7 13 11 NA NA NA NA NA NA 33177 XM_044314091.1 0 1 0 0 33 NA NA NA NA NA NA 33178 XR_006394779.1 0 0 1 0 7 NA NA NA NA NA NA 33179 XM_044318358.1 19 0 0 2 13 NA NA NA NA NA NA 33180 XM_044308225.1 14010 10786 8445 14684 23790 Q9U943 3.03e-77 Apolipophorins [Cleaved into: Apolipophorin-2 (Apolipophorin II) (apoLp-2); Apolipophorin-1 (Apolipophorin I) (apoLp-1)] Locusta migratoria (Migratory locust) Wnt signaling pathway [GO:0016055] GO:0005319; GO:0005576; GO:0008289; GO:0016055 33181 XM_044308225.1 14010 10786 8445 14684 23790 Q9U943 2.29e-27 Apolipophorins [Cleaved into: Apolipophorin-2 (Apolipophorin II) (apoLp-2); Apolipophorin-1 (Apolipophorin I) (apoLp-1)] Locusta migratoria (Migratory locust) Wnt signaling pathway [GO:0016055] GO:0005319; GO:0005576; GO:0008289; GO:0016055 33182 XM_029338021.2 312 157 143 169 300 Q8RWN2 1.51e-52 Protein ZINC INDUCED FACILITATOR 1 Arabidopsis thaliana (Mouse-ear cress) regulation of stomatal closure [GO:0090333]; response to nematode [GO:0009624]; response to zinc ion [GO:0010043]; zinc ion homeostasis [GO:0055069] GO:0005886; GO:0009624; GO:0009705; GO:0010043; GO:0022821; GO:0055069; GO:0090333 33183 XR_006398088.1 30 31 32 51 43 NA NA NA NA NA NA 33184 XM_044320554.1 59 39 105 119 51 NA NA NA NA NA NA 33185 XM_029335400.2 168 12 28 7 54 NA NA NA NA NA NA 33186 XM_044324746.1 0 50 39 67 36 Q9UKP5 8e-95 A disintegrin and metalloproteinase with thrombospondin motifs 6 (ADAM-TS 6) (ADAM-TS6) (ADAMTS-6) (EC 3.4.24.-) Homo sapiens (Human) aorta development [GO:0035904]; cardiac septum development [GO:0003279]; coronary vasculature development [GO:0060976]; extracellular matrix organization [GO:0030198]; kidney development [GO:0001822]; proteolysis [GO:0006508] GO:0001822; GO:0003279; GO:0004222; GO:0005576; GO:0006508; GO:0008237; GO:0030198; GO:0031012; GO:0035904; GO:0046872; GO:0060976 33187 XR_006391403.1 420 237 275 226 309 NA NA NA NA NA NA 33188 XM_029347824.2 209 79 0 147 70 Q14642 4.61e-117 Inositol polyphosphate-5-phosphatase A (EC 3.1.3.56) (43 kDa inositol polyphosphate 5-phosphatase) (Type I inositol 1,4,5-trisphosphate 5-phosphatase) (5PTase) Homo sapiens (Human) inositol phosphate dephosphorylation [GO:0046855]; inositol phosphate metabolic process [GO:0043647]; inositol phosphate-mediated signaling [GO:0048016]; negative regulation of neuron death [GO:1901215]; phosphatidylinositol dephosphorylation [GO:0046856] GO:0004445; GO:0005886; GO:0016020; GO:0030425; GO:0042731; GO:0043647; GO:0046855; GO:0046856; GO:0048016; GO:0052658; GO:0052659; GO:1901215 33189 XM_029331232.2 53 55 74 110 204 Q4QRH7 6.03e-84 Peroxisomal membrane protein PEX16 (Peroxin-16) (Peroxisomal biogenesis factor 16) Danio rerio (Zebrafish) (Brachydanio rerio) peroxisome organization [GO:0007031] GO:0005778; GO:0007031 33190 XM_044316125.1 0 0 0 2 6 NA NA NA NA NA NA 33191 XM_029337418.2 0 0 0 111 0 NA NA NA NA NA NA 33192 XR_003827369.2 0 62 51 86 105 NA NA NA NA NA NA 33193 XM_044309057.1 60 20 53 47 17 Q3UQ28 5.03e-31 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 33194 XM_044309057.1 60 20 53 47 17 Q3UQ28 2.52e-28 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 33195 XM_044313509.1 9 31 7 137 420 NA NA NA NA NA NA 33196 XM_029340310.2 444 239 166 270 246 P35610 6.68e-137 Sterol O-acyltransferase 1 (EC 2.3.1.26) (Acyl-coenzyme A:cholesterol acyltransferase 1) (ACAT-1) (Cholesterol acyltransferase 1) Homo sapiens (Human) cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; cholesterol storage [GO:0010878]; low-density lipoprotein particle clearance [GO:0034383]; macrophage derived foam cell differentiation [GO:0010742]; positive regulation of amyloid precursor protein biosynthetic process [GO:0042986]; very-low-density lipoprotein particle assembly [GO:0034379] GO:0000062; GO:0004772; GO:0005783; GO:0005789; GO:0008203; GO:0008374; GO:0010742; GO:0010878; GO:0015485; GO:0016020; GO:0033344; GO:0034379; GO:0034383; GO:0034736; GO:0042632; GO:0042802; GO:0042986 33197 XM_044325943.1 0 0 0 0 9 NA NA NA NA NA NA 33198 XM_044307216.1 6 0 110 0 0 NA NA NA NA NA NA 33199 XM_029356139.2 29 0 72 214 0 NA NA NA NA NA NA 33200 XM_029357412.2 616 84 255 356 700 Q9Z0U4 2.64e-57 Gamma-aminobutyric acid type B receptor subunit 1 (GABA-B receptor 1) (GABA-B-R1) (GABA-BR1) (GABABR1) (Gb1) Rattus norvegicus (Rat) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; chemical synaptic transmission [GO:0007268]; chemical synaptic transmission, postsynaptic [GO:0099565]; G protein-coupled receptor signaling pathway [GO:0007186]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of dopamine secretion [GO:0033602]; negative regulation of epinephrine secretion [GO:0032811]; negative regulation of gamma-aminobutyric acid secretion [GO:0014053]; negative regulation of synaptic transmission [GO:0050805]; neuron-glial cell signaling [GO:0150099]; osteoblast differentiation [GO:0001649]; positive regulation of glutamate secretion [GO:0014049]; positive regulation of growth hormone secretion [GO:0060124]; regulation of glutamate secretion [GO:0014048]; regulation of postsynaptic membrane potential [GO:0060078]; response to ethanol [GO:0045471]; response to nicotine [GO:0035094]; synaptic transmission, GABAergic [GO:0051932] GO:0001649; GO:0004888; GO:0004965; GO:0005615; GO:0005737; GO:0005789; GO:0005886; GO:0007186; GO:0007193; GO:0007194; GO:0007214; GO:0007268; GO:0008021; GO:0008285; GO:0014048; GO:0014049; GO:0014053; GO:0016020; GO:0030673; GO:0031966; GO:0032811; GO:0033602; GO:0035094; GO:0038037; GO:0038039; GO:0042734; GO:0043005; GO:0043025; GO:0043197; GO:0043198; GO:0043204; GO:0043231; GO:0045121; GO:0045211; GO:0045471; GO:0046982; GO:0050805; GO:0051932; GO:0060078; GO:0060124; GO:0097060; GO:0098685; GO:0098793; GO:0098978; GO:0098982; GO:0099565; GO:0099579; GO:0150047; GO:0150099; GO:1902710; GO:1902712; GO:1990430 33201 XM_029351094.2 717 397 308 333 348 Q9N126 5.84e-59 Retinol dehydrogenase 8 (EC 1.1.1.300) (Photoreceptor outer segment all-trans retinol dehydrogenase) Bos taurus (Bovine) estrogen biosynthetic process [GO:0006703]; response to stimulus [GO:0050896]; retinol metabolic process [GO:0042572]; visual perception [GO:0007601] GO:0004303; GO:0004745; GO:0005829; GO:0006703; GO:0007601; GO:0016491; GO:0042572; GO:0042622; GO:0050896; GO:0052650 33202 XM_029334225.2 0 16 0 0 20 P25931 6.06e-34 RYamide receptor (Neuropeptide Y-like receptor) (NPY-R) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218] GO:0001653; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0016020 33203 XM_029336656.2 0 0 0 2 6 NA NA NA NA NA NA 33204 XM_044313568.1 57 0 626 173 1788 Q02253 0 Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial (MMSDH) (Malonate-semialdehyde dehydrogenase [acylating]) (EC 1.2.1.18) (EC 1.2.1.27) (Aldehyde dehydrogenase family 6 member A1) Rattus norvegicus (Rat) beta-alanine catabolic process [GO:0019484]; brown fat cell differentiation [GO:0050873]; thymine catabolic process [GO:0006210]; thymine metabolic process [GO:0019859]; valine catabolic process [GO:0006574]; valine metabolic process [GO:0006573] GO:0000062; GO:0004491; GO:0005739; GO:0006210; GO:0006573; GO:0006574; GO:0016790; GO:0018478; GO:0019484; GO:0019859; GO:0050873; GO:0102662 33205 XM_044324941.1 285 312 172 271 181 NA NA NA NA NA NA 33206 XM_044326177.1 0 0 0 0 9 NA NA NA NA NA NA 33207 XM_029352118.2 58 86 0 94 115 NA NA NA NA NA NA 33208 XM_029343180.2 159 136 95 277 183 NA NA NA NA NA NA 33209 XM_029330803.2 286 444 221 347 192 NA NA NA NA NA NA 33210 XM_029333618.2 15930 11895 8519 15778 13489 Q2F7Z7 1.17e-29 Transmembrane protein 59 Sus scrofa (Pig) autophagy [GO:0006914]; positive regulation of autophagy [GO:0010508] GO:0000139; GO:0005764; GO:0005765; GO:0005770; GO:0005886; GO:0006914; GO:0010508; GO:0031902 33211 XR_006392339.1 4 0 5 50 5 NA NA NA NA NA NA 33212 XM_029349997.2 31 3 6 9 125 NA NA NA NA NA NA 33213 XM_044321196.1 2298 1717 2160 1928 1386 A3KNS9 4.1e-23 All-trans retinoic acid-induced differentiation factor (Apoptosis-related protein 3) (APR-3) Danio rerio (Zebrafish) (Brachydanio rerio) anatomical structure development [GO:0048856]; cell differentiation [GO:0030154]; negative regulation of osteoblast proliferation [GO:0033689]; negative regulation of protein catabolic process [GO:0042177]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of gene expression [GO:0010468] GO:0005635; GO:0005886; GO:0010468; GO:0030154; GO:0030501; GO:0033689; GO:0042177; GO:0043231; GO:0045669; GO:0048471; GO:0048856 33214 XM_044308188.1 0 0 0 294 0 Q9V9A7 1.11e-163 Probable methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCase subunit beta) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 2) (3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta) Drosophila melanogaster (Fruit fly) coenzyme A metabolic process [GO:0015936]; leucine catabolic process [GO:0006552]; regulation of eclosion [GO:0007563] GO:0004485; GO:0005524; GO:0005739; GO:0005759; GO:0006552; GO:0007563; GO:0015936; GO:1905202 33215 XR_003827435.2 29 0 41 0 60 NA NA NA NA NA NA 33216 XM_029344130.2 797 8 107 210 11 P02720 8.58e-69 Phosphatidylcholine transfer protein (PC-TP) (START domain-containing protein 2) (StARD2) (StAR-related lipid transfer protein 2) Bos taurus (Bovine) phospholipid transport [GO:0015914] GO:0005737; GO:0008525; GO:0015914; GO:0031210 33217 XM_044323163.1 0 0 0 0 20 NA NA NA NA NA NA 33218 XM_044311023.1 5 0 8 2 7 NA NA NA NA NA NA 33219 XM_029323670.2 811 750 884 1180 669 NA NA NA NA NA NA 33220 XM_044307418.1 94 38 15 54 14 NA NA NA NA NA NA 33221 XM_044312984.1 53 24 17 39 78 NA NA NA NA NA NA 33222 XM_044311226.1 98 31 44 14 24 B3EWZ5 8.22e-24 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 33223 XM_044311226.1 98 31 44 14 24 B3EWZ5 5.43e-22 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 33224 XM_044311226.1 98 31 44 14 24 B3EWZ5 8.71e-22 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 33225 XM_044311226.1 98 31 44 14 24 B3EWZ5 1.8e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 33226 XM_044311226.1 98 31 44 14 24 B3EWZ5 4.41e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 33227 XM_044311226.1 98 31 44 14 24 B3EWZ5 6.56e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 33228 XR_003827020.2 1 0 9 2 3 NA NA NA NA NA NA 33229 XM_044314552.1 0 45 1 0 4 Q80WG5 8.72e-77 Volume-regulated anion channel subunit LRRC8A (Leucine-rich repeat-containing protein 8A) (Protein ebouriffe) (ebo) Mus musculus (Mouse) anion transmembrane transport [GO:0098656]; anion transport [GO:0006820]; aspartate transmembrane transport [GO:0015810]; cell volume homeostasis [GO:0006884]; cellular glucose homeostasis [GO:0001678]; chloride transmembrane transport [GO:1902476]; cyclic-GMP-AMP transmembrane import across plasma membrane [GO:0140361]; positive regulation of insulin secretion [GO:0032024]; positive regulation of myoblast differentiation [GO:0045663]; pre-B cell differentiation [GO:0002329]; protein hexamerization [GO:0034214]; response to osmotic stress [GO:0006970]; spermatogenesis [GO:0007283]; taurine transport [GO:0015734] GO:0001678; GO:0002329; GO:0005225; GO:0005253; GO:0005765; GO:0005886; GO:0006820; GO:0006884; GO:0006970; GO:0007283; GO:0009986; GO:0015734; GO:0015810; GO:0016020; GO:0032024; GO:0034214; GO:0034702; GO:0042802; GO:0045663; GO:0098656; GO:0140360; GO:0140361; GO:1902476 33230 XM_029352332.2 746 720 312 758 750 F1MMV1 1.06e-162 EF-hand domain-containing family member B (Cilia- and flagella-associated protein 21) Bos taurus (Bovine) calcium ion transport [GO:0006816]; negative regulation of protein binding [GO:0032091]; regulation of calcineurin-NFAT signaling cascade [GO:0070884]; regulation of store-operated calcium entry [GO:2001256] GO:0005879; GO:0006816; GO:0032091; GO:0061891; GO:0070884; GO:2001256 33231 XM_029324259.2 36 23 319 172 120 NA NA NA NA NA NA 33232 XM_044325742.1 9 0 28 3 45 NA NA NA NA NA NA 33233 XR_006392791.1 62 8 57 20 241 NA NA NA NA NA NA 33234 XM_044308701.1 87 136 0 131 0 NA NA NA NA NA NA 33235 XM_029357135.2 270 0 0 141 223 NA NA NA NA NA NA 33236 XM_044309311.1 0 0 1 8 0 NA NA NA NA NA NA 33237 XM_044326470.1 20 3 37 4 54 NA NA NA NA NA NA 33238 XM_029355680.2 774 517 623 1344 1294 NA NA NA NA NA NA 33239 XM_044327102.1 54 43 119 39 76 Q94K49 8.15e-37 Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1 (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) epigenetic regulation of gene expression [GO:0040029] GO:0003682; GO:0004518; GO:0005634; GO:0035098; GO:0035102; GO:0040029; GO:0046872 33240 XM_029342038.2 887 873 4 641 463 Q28772 2.71e-31 Transcription factor 12 (TCF-12) (DNA-binding protein HTF4) (E-box-binding protein) (Transcription factor HTF-4) Papio hamadryas (Hamadryas baboon) cell differentiation [GO:0030154]; nervous system development [GO:0007399]; positive regulation of neuron differentiation [GO:0045666]; response to gonadotropin-releasing hormone [GO:0097210] GO:0005634; GO:0007399; GO:0030154; GO:0045666; GO:0046982; GO:0070888; GO:0097210 33241 XM_029343592.2 4559 4770 2176 2680 1030 NA NA NA NA NA NA 33242 XM_029335865.2 29 0 0 29 0 Q9HA64 2.19e-118 Ketosamine-3-kinase (EC 2.7.1.172) (Fructosamine-3-kinase-related protein) (FN3K-RP) (FN3K-related protein) (Protein-psicosamine 3-kinase FN3KRP) (EC 2.7.1.-) Homo sapiens (Human) phosphorylation [GO:0016310]; post-translational protein modification [GO:0043687] GO:0005524; GO:0005829; GO:0016301; GO:0016310; GO:0043687; GO:0102193 33243 XM_044307125.1 0 0 5 7 14 Q9U6Y6 3.65e-110 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 33244 XM_029357607.2 366 358 216 542 536 Q61858 3.2e-40 G patch domain and ankyrin repeat-containing protein 1 (G5 protein) (HLA-B-associated transcript 4) Mus musculus (Mouse) NA GO:0003676 33245 XR_006396958.1 314 142 187 222 541 Q8BZ20 1.43e-59 Protein mono-ADP-ribosyltransferase PARP12 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 12) (ARTD12) (Poly [ADP-ribose] polymerase 12) (PARP-12) (Zinc finger CCCH domain-containing protein 1) Mus musculus (Mouse) protein auto-ADP-ribosylation [GO:0070213] GO:0003950; GO:0005634; GO:0016779; GO:0046872; GO:0070213; GO:0140803; GO:1990404 33246 XM_029347167.2 0 0 0 26 0 NA NA NA NA NA NA 33247 XR_006395004.1 246 284 197 298 357 NA NA NA NA NA NA 33248 XM_044327715.1 60 168 47 110 266 NA NA NA NA NA NA 33249 XM_044318691.1 683 393 308 470 737 Q6GN08 0 NA NA NA NA 33250 XM_029344772.2 1081 720 452 786 897 P52292 0 Importin subunit alpha-1 (Karyopherin subunit alpha-2) (RAG cohort protein 1) (SRP1-alpha) Homo sapiens (Human) DNA metabolic process [GO:0006259]; entry of viral genome into host nucleus through nuclear pore complex via importin [GO:0075506]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of viral life cycle [GO:1903902]; protein import into nucleus [GO:0006606]; regulation of DNA recombination [GO:0000018] GO:0000018; GO:0000139; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0005789; GO:0005829; GO:0006259; GO:0006606; GO:0006607; GO:0008139; GO:0016020; GO:0042564; GO:0042826; GO:0043657; GO:0061608; GO:0075506; GO:1903902 33251 XM_029351288.2 686 944 560 377 359 Q0VCJ8 6.73e-72 Protein-L-histidine N-pros-methyltransferase (EC 2.1.1.-) (Methyltransferase-like protein 9) Bos taurus (Bovine) NA GO:0005739; GO:0005783; GO:0106370 33252 XM_029351288.2 686 944 560 377 359 Q0VCJ8 6.73e-72 Protein-L-histidine N-pros-methyltransferase (EC 2.1.1.-) (Methyltransferase-like protein 9) Bos taurus (Bovine) NA GO:0005739; GO:0005783; GO:0106370 33253 XM_029329191.2 50 0 0 0 1119 Q63413 0 Spliceosome RNA helicase Ddx39b (EC 3.6.4.13) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (DEAD box protein Uap56) Rattus norvegicus (Rat) liver development [GO:0001889]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of translation [GO:0045727]; positive regulation of vascular associated smooth muscle cell proliferation [GO:1904707]; RNA secondary structure unwinding [GO:0010501]; RNA splicing [GO:0008380]; spliceosomal complex assembly [GO:0000245]; viral mRNA export from host cell nucleus [GO:0046784] GO:0000245; GO:0000346; GO:0000398; GO:0001889; GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005681; GO:0005687; GO:0005688; GO:0005737; GO:0006406; GO:0008186; GO:0008380; GO:0010501; GO:0016363; GO:0016607; GO:0016887; GO:0017070; GO:0030621; GO:0032786; GO:0032991; GO:0042802; GO:0043008; GO:0044877; GO:0045727; GO:0046784; GO:0061051; GO:1904707; GO:2000002; GO:2000573 33254 XM_029347153.2 27 12 11 26 2 NA NA NA NA NA NA 33255 XR_006395326.1 28 16 31 39 77 NA NA NA NA NA NA 33256 XM_029323999.2 14 0 120 71 45 A8E7N9 9.78e-40 Growth/differentiation factor 6-B (GDF-6-B) (Growth differentiation factor 6b) (Protein dynamo) Danio rerio (Zebrafish) (Brachydanio rerio) positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; SMAD protein signal transduction [GO:0060395] GO:0005125; GO:0005615; GO:0008083; GO:0010862; GO:0060395 33257 XM_029334867.2 710 585 533 449 381 O94979 0 Protein transport protein Sec31A (ABP125) (ABP130) (SEC31-like protein 1) (SEC31-related protein A) (Web1-like protein) Homo sapiens (Human) COPII-coated vesicle cargo loading [GO:0090110]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; response to calcium ion [GO:0051592] GO:0005198; GO:0005737; GO:0005783; GO:0005789; GO:0005829; GO:0006886; GO:0006888; GO:0007029; GO:0012507; GO:0030120; GO:0030127; GO:0030134; GO:0043231; GO:0048306; GO:0048471; GO:0051592; GO:0070971; GO:0090110 33258 XM_029334867.2 710 585 533 449 381 O94979 2.96e-28 Protein transport protein Sec31A (ABP125) (ABP130) (SEC31-like protein 1) (SEC31-related protein A) (Web1-like protein) Homo sapiens (Human) COPII-coated vesicle cargo loading [GO:0090110]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; response to calcium ion [GO:0051592] GO:0005198; GO:0005737; GO:0005783; GO:0005789; GO:0005829; GO:0006886; GO:0006888; GO:0007029; GO:0012507; GO:0030120; GO:0030127; GO:0030134; GO:0043231; GO:0048306; GO:0048471; GO:0051592; GO:0070971; GO:0090110 33259 XM_044320436.1 53 36 10 103 0 NA NA NA NA NA NA 33260 XM_044309195.1 38 0 7 0 46 Q3UQ28 2.44e-32 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 33261 XM_044309195.1 38 0 7 0 46 Q3UQ28 4.19e-27 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 33262 XM_029339171.2 0 149 47 213 190 Q5VTY9 1.34e-53 Protein-cysteine N-palmitoyltransferase HHAT (EC 2.3.1.-) (Hedgehog acyltransferase) (Melanoma antigen recognized by T-cells 2) (MART-2) (Skinny hedgehog protein 1) Homo sapiens (Human) N-terminal peptidyl-L-cysteine N-palmitoylation [GO:0018009]; protein palmitoylation [GO:0018345]; smoothened signaling pathway [GO:0007224] GO:0000139; GO:0005525; GO:0005783; GO:0005789; GO:0005794; GO:0007224; GO:0008374; GO:0016409; GO:0016746; GO:0018009; GO:0018345 33263 XM_029327671.2 3 0 23 13 25 P95648 1.99e-40 Protein CbbX Cereibacter sphaeroides (Rhodobacter sphaeroides) NA GO:0005524; GO:0016887 33264 XM_044321829.1 109 99 35 40 157 NA NA NA NA NA NA 33265 XM_044319923.1 8 0 50 15 35 Q5XJN2 4.12e-49 Gamma-interferon-inducible lysosomal thiol reductase (EC 1.8.-.-) (Gamma-interferon-inducible protein IP-30) Danio rerio (Zebrafish) (Brachydanio rerio) immune system process [GO:0002376] GO:0002376; GO:0005576; GO:0005764; GO:0016491; GO:0016667; GO:0016671; GO:0047134 33266 XM_044323954.1 1 0 7 0 27 NA NA NA NA NA NA 33267 XM_029338542.2 1852 1676 2916 3699 2419 Q9DDT2 3.2e-22 Phosphoinositide 3-kinase adapter protein 1 (B-cell adapter for phosphoinositide 3-kinase) (B-cell phosphoinositide 3-kinase adapter protein 1) Gallus gallus (Chicken) cellular response to insulin stimulus [GO:0032869]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; regulation of inflammatory response [GO:0050727]; regulation of kinase activity [GO:0043549]; regulation of phosphorylation [GO:0042325]; toll-like receptor 2 signaling pathway [GO:0034134]; toll-like receptor 4 signaling pathway [GO:0034142]; toll-like receptor 7 signaling pathway [GO:0034154]; toll-like receptor 9 signaling pathway [GO:0034162]; TOR signaling [GO:0031929] GO:0005102; GO:0005829; GO:0005886; GO:0014068; GO:0016020; GO:0031929; GO:0032869; GO:0034134; GO:0034142; GO:0034154; GO:0034162; GO:0036312; GO:0042325; GO:0043549; GO:0050727 33268 XM_029333578.2 3013 1259 1724 2310 839 Q76KP1 4.57e-75 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Homo sapiens (Human) NA GO:0008376; GO:0032580; GO:0033842 33269 XM_029333578.2 3013 1259 1724 2310 839 Q76KP1 1.33e-36 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Homo sapiens (Human) NA GO:0008376; GO:0032580; GO:0033842 33270 XM_029340220.2 1013 602 527 679 630 Q4VBS4 3.23e-103 Methionine aminopeptidase 1D, mitochondrial (MAP 1D) (MetAP 1D) (EC 3.4.11.18) (Methionyl aminopeptidase type 1D, mitochondrial) (Peptidase M 1D) Danio rerio (Zebrafish) (Brachydanio rerio) protein initiator methionine removal [GO:0070084]; proteolysis [GO:0006508] GO:0005739; GO:0006508; GO:0046872; GO:0070006; GO:0070084 33271 XM_044326128.1 0 0 9 0 0 Q99J85 8.56e-37 Neuronal pentraxin receptor Mus musculus (Mouse) neuron projection development [GO:0031175]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; regulation of postsynaptic specialization assembly [GO:0099150] GO:0005615; GO:0005886; GO:0008029; GO:0019903; GO:0031175; GO:0044877; GO:0046872; GO:0098962; GO:0098978; GO:0099150; GO:0099645 33272 XM_044326528.1 203 77 111 68 111 Q9NBX4 8.76e-46 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 33273 XM_044316629.1 0 0 0 0 98 NA NA NA NA NA NA 33274 XM_029349368.2 24 5 32 4 68 Q4R4A8 8.33e-66 Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C (EC 2.4.1.145) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVc) (GnT-IVc) (N-acetylglucosaminyltransferase IVc) (UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVc) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0008454; GO:0046872 33275 XM_044327555.1 24 0 0 9 102 NA NA NA NA NA NA 33276 XM_029345227.2 305 141 102 291 379 Q6NVR9 0 ATPase family AAA domain-containing protein 3 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005524; GO:0005743; GO:0016887; GO:0042645 33277 XM_044317454.1 0 2 3 6 0 NA NA NA NA NA NA 33278 XR_006392027.1 0 5 228 568 10 NA NA NA NA NA NA 33279 XM_029346928.2 457 671 303 626 667 P33947 2e-115 ER lumen protein-retaining receptor 2 (ERD2-like protein 1) (ELP-1) (KDEL endoplasmic reticulum protein retention receptor 2) (KDEL receptor 2) Homo sapiens (Human) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; protein retention in ER lumen [GO:0006621]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] GO:0000139; GO:0005046; GO:0005783; GO:0005789; GO:0005801; GO:0006621; GO:0006888; GO:0006890; GO:0015031; GO:0016020; GO:0030133; GO:0030663; GO:0035437; GO:0046923 33280 XM_029327793.2 275 340 275 852 276 NA NA NA NA NA NA 33281 XM_044327673.1 277 0 0 0 0 Q5FWL3 5.66e-141 E3 ubiquitin-protein ligase NRDP1 (EC 2.3.2.27) (RING finger protein 41) (RING-type E3 ubiquitin transferase NRDP1) Xenopus laevis (African clawed frog) extrinsic apoptotic signaling pathway [GO:0097191]; protein polyubiquitination [GO:0000209] GO:0000209; GO:0004842; GO:0046872; GO:0061630; GO:0097191 33282 XM_029349217.2 1874 1796 1614 1766 2652 Q5SXY1 1.51e-23 Cytospin-B (Sperm antigen with calponin homology and coiled-coil domains 1) Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; associative learning [GO:0008306]; blastocyst development [GO:0001824] GO:0001650; GO:0001824; GO:0005634; GO:0005654; GO:0005737; GO:0005815; GO:0005829; GO:0008306; GO:0016020; GO:0030036; GO:0031941; GO:0043231; GO:0045177 33283 XM_044321066.1 1 0 11 2 18 NA NA NA NA NA NA 33284 XM_029333294.2 420 342 377 480 445 Q9M390 2.19e-85 Protein NRT1/ PTR FAMILY 8.1 (AtNPF8.1) (Peptide transporter PTR1) Arabidopsis thaliana (Mouse-ear cress) dipeptide transport [GO:0042938]; nitrogen compound metabolic process [GO:0006807]; protein transport [GO:0015031]; transmembrane transport [GO:0055085]; tripeptide transport [GO:0042939] GO:0005886; GO:0006807; GO:0009506; GO:0015031; GO:0016020; GO:0022857; GO:0042937; GO:0042938; GO:0042939; GO:0055085; GO:0071916 33285 XM_029351938.2 36 23 20 32 62 NA NA NA NA NA NA 33286 XR_006394478.1 12 0 2 0 0 NA NA NA NA NA NA 33287 XM_029356732.2 2747 2554 1971 2719 3296 Q5RBR8 4.68e-30 Eukaryotic translation initiation factor 4H (eIF-4H) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003723; GO:0003743; GO:0048471 33288 XM_029340407.2 754 2432 481 1661 1978 Q99943 5.91e-49 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 1) (1-AGP acyltransferase 1) (1-AGPAT 1) (Lysophosphatidic acid acyltransferase alpha) (LPAAT-alpha) (Protein G15) Homo sapiens (Human) CDP-diacylglycerol biosynthetic process [GO:0016024]; phosphatidic acid biosynthetic process [GO:0006654]; phospholipid metabolic process [GO:0006644]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine-mediated signaling pathway [GO:0001961] GO:0001819; GO:0001961; GO:0003841; GO:0005783; GO:0005789; GO:0006644; GO:0006654; GO:0016020; GO:0016024 33289 XR_006396788.1 210 104 36 169 190 NA NA NA NA NA NA 33290 XM_044319549.1 48 136 127 102 94 NA NA NA NA NA NA 33291 XM_044318653.1 14 1 8 4 17 Q9UBS5 1.09e-29 Gamma-aminobutyric acid type B receptor subunit 1 (GABA-B receptor 1) (GABA-B-R1) (GABA-BR1) (GABABR1) (Gb1) Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of dopamine secretion [GO:0033602]; negative regulation of epinephrine secretion [GO:0032811]; negative regulation of gamma-aminobutyric acid secretion [GO:0014053]; negative regulation of synaptic transmission [GO:0050805]; neuron-glial cell signaling [GO:0150099]; osteoblast differentiation [GO:0001649]; positive regulation of glutamate secretion [GO:0014049]; positive regulation of growth hormone secretion [GO:0060124]; response to ethanol [GO:0045471]; response to nicotine [GO:0035094]; synaptic transmission, GABAergic [GO:0051932] GO:0001649; GO:0004888; GO:0004965; GO:0005615; GO:0005789; GO:0005886; GO:0007193; GO:0007194; GO:0007214; GO:0008021; GO:0008285; GO:0014049; GO:0014053; GO:0030673; GO:0031966; GO:0032811; GO:0033602; GO:0035094; GO:0038039; GO:0042734; GO:0043025; GO:0043197; GO:0043198; GO:0045121; GO:0045211; GO:0045471; GO:0046982; GO:0050805; GO:0051932; GO:0060124; GO:0098685; GO:0098978; GO:0098982; GO:0099579; GO:0150047; GO:0150099; GO:1902712; GO:1990430 33292 XM_044323129.1 208 227 112 84 12 P55210 7.67e-32 Caspase-7 (CASP-7) (EC 3.4.22.60) (Apoptotic protease Mch-3) (CMH-1) (ICE-like apoptotic protease 3) (ICE-LAP3) [Cleaved into: Caspase-7 subunit p20; Caspase-7 subunit p11] Homo sapiens (Human) apoptotic process [GO:0006915]; cellular response to staurosporine [GO:0072734]; defense response to bacterium [GO:0042742]; execution phase of apoptosis [GO:0097194]; extrinsic apoptotic signaling pathway [GO:0097191]; fibroblast apoptotic process [GO:0044346]; heart development [GO:0007507]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway [GO:0097193]; lymphocyte apoptotic process [GO:0070227]; neuron apoptotic process [GO:0051402]; positive regulation of apoptotic process [GO:0043065]; positive regulation of plasma membrane repair [GO:1905686]; protein processing [GO:0016485]; proteolysis [GO:0006508]; response to UV [GO:0009411] GO:0003723; GO:0004190; GO:0004197; GO:0005615; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006508; GO:0006915; GO:0006954; GO:0007507; GO:0008233; GO:0008234; GO:0008303; GO:0009411; GO:0016485; GO:0035556; GO:0042742; GO:0043065; GO:0044346; GO:0051402; GO:0070227; GO:0072734; GO:0097153; GO:0097191; GO:0097193; GO:0097194; GO:0097200; GO:1905686 33293 XM_029333948.2 1036 476 550 726 691 Q5FVJ6 1.56e-60 Seipin (Bernardinelli-Seip congenital lipodystrophy type 2 protein homolog) Rattus norvegicus (Rat) adipose tissue development [GO:0060612]; cytosolic lipolysis [GO:0061725]; fat cell differentiation [GO:0045444]; lipid droplet formation [GO:0140042]; lipid droplet organization [GO:0034389]; lipid storage [GO:0019915]; maintenance of location in cell [GO:0051651]; negative regulation of catalytic activity [GO:0043086]; negative regulation of lipid catabolic process [GO:0050995]; positive regulation of cold-induced thermogenesis [GO:0120162]; regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction [GO:0014853]; regulation of phosphatidic acid biosynthetic process [GO:1905693]; spermatid differentiation [GO:0048515] GO:0005543; GO:0005783; GO:0005789; GO:0005811; GO:0005829; GO:0014853; GO:0019915; GO:0034389; GO:0043086; GO:0045444; GO:0048515; GO:0050995; GO:0051651; GO:0060612; GO:0061725; GO:0120162; GO:0140042; GO:1905693 33294 XM_029353888.2 333 43 231 343 300 Q3UQ28 3.29e-30 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 33295 XM_029353888.2 333 43 231 343 300 Q3UQ28 4.39e-30 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 33296 XM_044308891.1 305 65 122 343 295 NA NA NA NA NA NA 33297 XM_029348832.2 499 663 443 786 743 NA NA NA NA NA NA 33298 XR_006391552.1 54 0 38 23 126 NA NA NA NA NA NA 33299 XR_003823834.2 9 12 8 27 38 NA NA NA NA NA NA 33300 XM_044311893.1 50 0 0 0 0 NA NA NA NA NA NA 33301 XR_003825415.2 0 2 0 8 10 NA NA NA NA NA NA 33302 XM_044329307.1 229 189 95 188 209 Q8AWD2 2.8e-170 Adenylyltransferase and sulfurtransferase MOCS3 (Molybdenum cofactor synthesis protein 3) [Includes: Molybdopterin-synthase adenylyltransferase (EC 2.7.7.80) (Adenylyltransferase MOCS3) (Sulfur carrier protein MOCS2A adenylyltransferase); Molybdopterin-synthase sulfurtransferase (EC 2.8.1.11) (Sulfur carrier protein MOCS2A sulfurtransferase) (Sulfurtransferase MOCS3)] Danio rerio (Zebrafish) (Brachydanio rerio) Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; protein urmylation [GO:0032447]; tRNA thio-modification [GO:0034227]; tRNA wobble position uridine thiolation [GO:0002143]; tRNA wobble uridine modification [GO:0002098] GO:0002098; GO:0002143; GO:0004792; GO:0005524; GO:0005737; GO:0005829; GO:0006777; GO:0016779; GO:0016783; GO:0032447; GO:0034227; GO:0042292; GO:0046872; GO:0061604; GO:0061605 33303 XR_006393356.1 14 0 0 0 0 NA NA NA NA NA NA 33304 XM_044307166.1 347 281 420 418 740 O15381 0 Nuclear valosin-containing protein-like (NVLp) (Nuclear VCP-like protein) Homo sapiens (Human) positive regulation of protein binding [GO:0032092]; positive regulation of telomerase activity [GO:0051973]; regulation of protein localization to nucleolus [GO:1904749]; ribosomal large subunit biogenesis [GO:0042273]; ribosome biogenesis [GO:0042254]; rRNA processing [GO:0006364] GO:0003723; GO:0005524; GO:0005634; GO:0005654; GO:0005697; GO:0005730; GO:0006364; GO:0016020; GO:0016887; GO:0032092; GO:0042254; GO:0042273; GO:0051973; GO:1904749; GO:1990275 33305 XM_044328734.1 22 42 19 2 18 NA NA NA NA NA NA 33306 XM_044325401.1 245 113 206 191 470 O15460 2.14e-135 Prolyl 4-hydroxylase subunit alpha-2 (4-PH alpha-2) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-2) Homo sapiens (Human) peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401] GO:0004656; GO:0005506; GO:0005654; GO:0005783; GO:0005788; GO:0005829; GO:0009055; GO:0018401; GO:0031418; GO:0043231 33307 XM_044327011.1 1105 1072 552 1104 881 NA NA NA NA NA NA 33308 XM_044326603.1 215 277 45 134 99 NA NA NA NA NA NA 33309 XM_029333322.2 2208 1689 1887 2078 1463 NA NA NA NA NA NA 33310 XM_029357374.2 17 22 38 127 17 P54131 9.04e-67 Neuronal acetylcholine receptor subunit alpha-7 Bos taurus (Bovine) calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; cognition [GO:0050890]; ion transmembrane transport [GO:0034220]; negative regulation of tumor necrosis factor production [GO:0032720]; nervous system process [GO:0050877]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAPK cascade [GO:0043410]; regulation of membrane potential [GO:0042391]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271] GO:0001540; GO:0001666; GO:0005231; GO:0005886; GO:0005892; GO:0006816; GO:0006874; GO:0007165; GO:0007268; GO:0007271; GO:0008284; GO:0015464; GO:0015643; GO:0017081; GO:0022848; GO:0030594; GO:0032720; GO:0034220; GO:0035094; GO:0042166; GO:0042391; GO:0042803; GO:0043005; GO:0043410; GO:0045202; GO:0045211; GO:0045766; GO:0050877; GO:0050890; GO:1904315 33311 XM_044324313.1 19 0 22 15 56 Q1XA76 1.8e-30 Acid-sensing ion channel 1 (ASIC1) (Amiloride-sensitive cation channel 2, neuronal) Gallus gallus (Chicken) cellular response to pH [GO:0071467]; protein homotrimerization [GO:0070207]; sodium ion transmembrane transport [GO:0035725] GO:0005886; GO:0015280; GO:0035725; GO:0042802; GO:0044736; GO:0070207; GO:0071467 33312 XM_044325145.1 38 62 24 38 101 NA NA NA NA NA NA 33313 XR_006397882.1 132 114 88 101 53 NA NA NA NA NA NA 33314 XM_044309472.1 5 11 4 6 15 NA NA NA NA NA NA 33315 XM_044328723.1 78 25 213 35 92 O15457 0 MutS protein homolog 4 (hMSH4) Homo sapiens (Human) female gamete generation [GO:0007292]; homologous chromosome pairing at meiosis [GO:0007129]; mismatch repair [GO:0006298]; ovarian follicle development [GO:0001541]; reciprocal meiotic recombination [GO:0007131]; spermatogenesis [GO:0007283] GO:0000795; GO:0001541; GO:0003677; GO:0003690; GO:0005524; GO:0005634; GO:0005694; GO:0005713; GO:0006298; GO:0007129; GO:0007131; GO:0007283; GO:0007292; GO:0030983; GO:0140664 33316 XM_029345096.2 287 373 362 1149 542 A2AKX3 6.82e-87 Probable helicase senataxin (EC 3.6.4.-) (Amyotrophic lateral sclerosis 4 protein homolog) (SEN1 homolog) Mus musculus (Mouse) cell differentiation [GO:0030154]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to oxidative stress [GO:0034599]; cellular response to retinoic acid [GO:0071300]; circadian rhythm [GO:0007623]; DNA recombination [GO:0006310]; DNA-templated transcription termination [GO:0006353]; double-strand break repair [GO:0006302]; fibroblast growth factor receptor signaling pathway [GO:0008543]; MAPK cascade [GO:0000165]; mRNA splice site selection [GO:0006376]; negative regulation of apoptotic process [GO:0043066]; nervous system development [GO:0007399]; positive regulation of DNA-templated transcription initiation [GO:2000144]; positive regulation of neuron projection development [GO:0010976]; positive regulation of RNA splicing [GO:0033120]; positive regulation of termination of DNA-templated transcription [GO:0060566]; positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled [GO:2000806]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein kinase B signaling [GO:0043491]; spermatogenesis [GO:0007283]; termination of RNA polymerase II transcription [GO:0006369] GO:0000165; GO:0000228; GO:0000781; GO:0001147; GO:0003723; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0006302; GO:0006310; GO:0006353; GO:0006369; GO:0006376; GO:0006974; GO:0007283; GO:0007399; GO:0007623; GO:0008543; GO:0010976; GO:0016604; GO:0016787; GO:0030154; GO:0030424; GO:0030426; GO:0033120; GO:0034599; GO:0042802; GO:0043066; GO:0043491; GO:0044344; GO:0045171; GO:0045944; GO:0060566; GO:0070301; GO:0071300; GO:2000144; GO:2000806 33317 XM_044320070.1 475 264 335 395 379 NA NA NA NA NA NA 33318 XM_029335222.2 1370 1183 868 1067 1246 Q8BQM4 4.07e-46 HEAT repeat-containing protein 3 Mus musculus (Mouse) protein import into nucleus [GO:0006606]; ribosomal large subunit biogenesis [GO:0042273] GO:0006606; GO:0042273; GO:0051082 33319 XM_029335222.2 1370 1183 868 1067 1246 Q8BQM4 1.58e-44 HEAT repeat-containing protein 3 Mus musculus (Mouse) protein import into nucleus [GO:0006606]; ribosomal large subunit biogenesis [GO:0042273] GO:0006606; GO:0042273; GO:0051082 33320 XM_044322648.1 2 0 2 4 7 NA NA NA NA NA NA 33321 XM_044312770.1 51 33 241 238 36 P35604 2.1e-72 Coatomer subunit zeta-1 (Zeta-1-coat protein) (Zeta-1 COP) Bos taurus (Bovine) intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; toxin transport [GO:1901998] GO:0000139; GO:0006886; GO:0006890; GO:0006891; GO:0030126; GO:1901998 33322 XM_029332815.2 1236 832 678 901 1123 Q8TC07 5.66e-33 TBC1 domain family member 15 (GTPase-activating protein RAB7) (GAP for RAB7) (Rab7-GAP) Homo sapiens (Human) activation of GTPase activity [GO:0090630]; regulation of GTPase activity [GO:0043087] GO:0005096; GO:0005576; GO:0005737; GO:0043087; GO:0090630 33323 XM_044317205.1 211 54 93 27 80 Q921G8 0 Gamma-tubulin complex component 2 (GCP-2) Mus musculus (Mouse) brain development [GO:0007420]; cytoplasmic microtubule organization [GO:0031122]; meiotic cell cycle [GO:0051321]; microtubule nucleation [GO:0007020]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; spindle assembly [GO:0051225] GO:0000278; GO:0000922; GO:0000923; GO:0000930; GO:0001764; GO:0005654; GO:0005813; GO:0005815; GO:0005829; GO:0005874; GO:0007020; GO:0007420; GO:0008275; GO:0031122; GO:0043015; GO:0051225; GO:0051321 33324 XM_029323915.2 456 186 98 236 427 NA NA NA NA NA NA 33325 XM_029332422.2 180 78 12 77 39 NA NA NA NA NA NA 33326 XM_029325328.2 0 3 1 3 10 NA NA NA NA NA NA 33327 XM_044324222.1 0 6 0 0 0 NA NA NA NA NA NA 33328 XM_029349679.2 12 0 0 0 1 Q9EQD2 4.76e-25 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 33329 XM_044316464.1 1 0 0 21 24 Q17RP2 2.35e-56 Tigger transposable element-derived protein 6 Homo sapiens (Human) NA GO:0003677; GO:0005634 33330 XM_029328542.2 487 833 798 1363 1018 P97846 3.92e-39 Contactin-associated protein 1 (Caspr) (Caspr1) (Neurexin IV) (Neurexin-4) (Paranodin) (p190) Rattus norvegicus (Rat) axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cytoskeleton organization [GO:0007010]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process [GO:0050905]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuronal action potential propagation [GO:0019227]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; postsynaptic density organization [GO:0097106]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; regulation of synapse maturation [GO:0090128] GO:0002175; GO:0007005; GO:0007010; GO:0007155; GO:0007409; GO:0016020; GO:0017124; GO:0019227; GO:0022010; GO:0022011; GO:0030424; GO:0030913; GO:0031175; GO:0033010; GO:0033270; GO:0042552; GO:0048786; GO:0048812; GO:0050884; GO:0050885; GO:0050905; GO:0071205; GO:0090128; GO:0097106; GO:0098529; GO:0098978; GO:1990227 33331 XM_029347176.2 14000 15018 10224 27558 15764 C3YWU0 4.28e-178 Alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucoside fucohydrolase) Branchiostoma floridae (Florida lancelet) (Amphioxus) fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139] GO:0004560; GO:0005576; GO:0005764; GO:0006004; GO:0016139 33332 XM_044311662.1 0 153 26 62 0 Q9CWQ0 5.69e-128 Diphthine methyl ester synthase (EC 2.1.1.314) (Diphthamide biosynthesis methyltransferase) Mus musculus (Mouse) methylation [GO:0032259]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183] GO:0004164; GO:0017183; GO:0032259 33333 XM_029354119.2 1302 1250 936 1265 1193 NA NA NA NA NA NA 33334 XM_029348899.2 20 10 7 9 46 NA NA NA NA NA NA 33335 XM_029344202.2 11 0 7 0 0 Q4HX89 3.81e-25 Protein BTN1 Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1) (Wheat head blight fungus) (Fusarium graminearum) amino acid transport [GO:0006865] GO:0005774; GO:0006865 33336 XM_044322408.1 1 1 5 12 27 NA NA NA NA NA NA 33337 XM_029351907.2 2595 3264 2019 5460 4546 Q99NH2 1.25e-58 Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP) Mus musculus (Mouse) apical constriction [GO:0003383]; bicellular tight junction assembly [GO:0070830]; cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell-cell adhesion [GO:0098609]; centrosome localization [GO:0051642]; establishment of cell polarity [GO:0030010]; establishment of centrosome localization [GO:0051660]; establishment of epithelial cell polarity [GO:0090162]; establishment or maintenance of cell polarity [GO:0007163]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; microtubule cytoskeleton organization [GO:0000226]; myelination in peripheral nervous system [GO:0022011]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; positive regulation of myelination [GO:0031643]; positive regulation of receptor internalization [GO:0002092]; protein localization [GO:0008104]; protein targeting to membrane [GO:0006612]; regulation of actin filament-based process [GO:0032970]; regulation of cellular localization [GO:0060341]; wound healing, spreading of cells [GO:0044319] GO:0000226; GO:0002092; GO:0003383; GO:0005546; GO:0005547; GO:0005737; GO:0005819; GO:0005886; GO:0005911; GO:0005912; GO:0005923; GO:0005938; GO:0006612; GO:0007049; GO:0007155; GO:0007163; GO:0008104; GO:0010801; GO:0012505; GO:0016324; GO:0019903; GO:0022011; GO:0030010; GO:0030054; GO:0031643; GO:0032266; GO:0032970; GO:0032991; GO:0033269; GO:0035091; GO:0042802; GO:0043025; GO:0043219; GO:0043220; GO:0043296; GO:0044295; GO:0044319; GO:0045197; GO:0051301; GO:0051642; GO:0051660; GO:0060341; GO:0070830; GO:0090162; GO:0098609; GO:0120157 33338 XM_044310605.1 223 181 255 115 375 Q96L58 4.87e-88 Beta-1,3-galactosyltransferase 6 (Beta-1,3-GalTase 6) (Beta3Gal-T6) (Beta3GalT6) (EC 2.4.1.134) (GAG GalTII) (Galactosyltransferase II) (Galactosylxylosylprotein 3-beta-galactosyltransferase) (UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6) Homo sapiens (Human) chondroitin sulfate biosynthetic process [GO:0030206]; glycosaminoglycan biosynthetic process [GO:0006024]; glycosaminoglycan metabolic process [GO:0030203]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; protein glycosylation [GO:0006486]; proteoglycan biosynthetic process [GO:0030166] GO:0000139; GO:0005794; GO:0005797; GO:0006024; GO:0006486; GO:0008194; GO:0015012; GO:0016020; GO:0016757; GO:0030166; GO:0030203; GO:0030206; GO:0032580; GO:0035250; GO:0047220 33339 XM_029336834.2 1926 1586 993 1726 1065 A7MBH5 2.29e-91 Outer dynein arm-docking complex subunit 3 (Coiled-coil domain-containing protein 151) Bos taurus (Bovine) brain development [GO:0007420]; cerebrospinal fluid circulation [GO:0090660]; cilium movement [GO:0003341]; determination of heart left/right asymmetry [GO:0061371]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; flagellated sperm motility [GO:0030317]; multicellular organism growth [GO:0035264]; outer dynein arm assembly [GO:0036158]; regulation of cilium assembly [GO:1902017]; spermatogenesis [GO:0007283] GO:0003341; GO:0005576; GO:0005814; GO:0005929; GO:0005930; GO:0007283; GO:0007420; GO:0030317; GO:0035253; GO:0035264; GO:0036064; GO:0036158; GO:0060287; GO:0061371; GO:0090660; GO:0097542; GO:0120228; GO:1902017 33340 XM_044314260.1 4 6 0 0 0 NA NA NA NA NA NA 33341 XM_029340517.2 645 249 302 583 361 Q12852 1.53e-159 Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine zipper bearing kinase) (DLK) (Leucine-zipper protein kinase) (ZPK) (MAPK-upstream kinase) (MUK) (Mixed lineage kinase) Homo sapiens (Human) intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; negative regulation of motor neuron apoptotic process [GO:2000672]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of protein kinase activity [GO:0045860]; post-translational protein modification [GO:0043687]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468] GO:0004672; GO:0004674; GO:0004706; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006468; GO:0007254; GO:0016020; GO:0018105; GO:0018107; GO:0019901; GO:0030426; GO:0035556; GO:0042803; GO:0043507; GO:0043539; GO:0043687; GO:0045860; GO:0045893; GO:0046777; GO:0070374; GO:0106310; GO:2000672 33342 XM_029325611.2 15 0 0 8 0 NA NA NA NA NA NA 33343 XM_044328180.1 6308 14362 2888 10856 8987 Q90YS3 1.35e-151 40S ribosomal protein S2 Ictalurus punctatus (Channel catfish) (Silurus punctatus) translation [GO:0006412] GO:0003723; GO:0003735; GO:0006412; GO:0015935 33344 XM_029350802.2 7 0 0 0 0 O16025 0 Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (AOS) (EC 4.2.1.-) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)] Plexaura homomalla (Black sea rod) arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; lipid oxidation [GO:0034440]; oxylipin biosynthetic process [GO:0031408] GO:0005506; GO:0005737; GO:0006633; GO:0009978; GO:0016020; GO:0019369; GO:0020037; GO:0031408; GO:0034440; GO:0047677 33345 XM_029329633.2 266 219 241 284 448 Q4V893 6.87e-35 GPALPP motifs-containing protein 1 Rattus norvegicus (Rat) NA NA 33346 XM_044309801.1 1947 1581 851 1621 3347 NA NA NA NA NA NA 33347 XR_006396639.1 141 445 246 377 431 NA NA NA NA NA NA 33348 XM_029347158.2 659 531 278 691 508 Q6ICB0 9.4e-64 Desumoylating isopeptidase 1 (DeSI-1) (EC 3.4.-.-) (PPPDE peptidase domain-containing protein 2) (Polyubiquitinated substrate transporter) (POST) Homo sapiens (Human) protein desumoylation [GO:0016926]; protein export from nucleus [GO:0006611]; protein modification by small protein removal [GO:0070646]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434] GO:0005634; GO:0005829; GO:0006611; GO:0016926; GO:0016929; GO:0032434; GO:0032991; GO:0042802; GO:0061676; GO:0070646 33349 XM_044324136.1 0 0 15 2 0 NA NA NA NA NA NA 33350 XM_029347776.2 6 2 13 0 13 NA NA NA NA NA NA 33351 XM_029350940.2 525 223 307 259 394 Q5I0M0 3.94e-78 Histone-lysine N-methyltransferase SETMAR (EC 2.1.1.357) (SET domain and mariner transposase fusion protein homolog) Rattus norvegicus (Rat) cell population proliferation [GO:0008283]; chromatin organization [GO:0006325]; DNA catabolic process, endonucleolytic [GO:0000737]; DNA double-strand break processing [GO:0000729]; DNA integration [GO:0015074]; double-strand break repair via nonhomologous end joining [GO:0006303]; histone H3-K36 dimethylation [GO:0097676]; histone H3-K36 methylation [GO:0010452]; histone H3-K4 methylation [GO:0051568]; histone methylation [GO:0016571]; mitotic DNA integrity checkpoint signaling [GO:0044774]; negative regulation of chromosome organization [GO:2001251]; negative regulation of DNA-templated transcription [GO:0045892]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity [GO:2000373]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; replication fork processing [GO:0031297] GO:0000014; GO:0000729; GO:0000737; GO:0003677; GO:0003690; GO:0003697; GO:0004519; GO:0005634; GO:0006303; GO:0006325; GO:0008270; GO:0008283; GO:0010452; GO:0015074; GO:0016571; GO:0031297; GO:0035861; GO:0042054; GO:0042800; GO:0042803; GO:0044547; GO:0044774; GO:0045892; GO:0046975; GO:0051568; GO:0090305; GO:0097676; GO:0140954; GO:2000373; GO:2001034; GO:2001251 33352 XM_029351122.2 16 73 2 8 51 NA NA NA NA NA NA 33353 XM_029328904.2 163 85 90 207 64 Q0R4F1 0 ATP-dependent DNA helicase PIF1 (EC 3.6.4.12) (DNA repair and recombination helicase PIF1) Xenopus laevis (African clawed frog) DNA recombination [GO:0006310]; DNA repair [GO:0006281]; mitochondrial genome maintenance [GO:0000002]; telomere maintenance [GO:0000723] GO:0000002; GO:0000723; GO:0003677; GO:0005524; GO:0005634; GO:0005739; GO:0006281; GO:0006310; GO:0016887; GO:0043139 33354 XM_044314672.1 0 5 4 0 83 NA NA NA NA NA NA 33355 XM_029340250.2 1689 1695 1450 1454 1485 NA NA NA NA NA NA 33356 XM_029345121.2 28 0 0 0 54 P56966 5.62e-99 Geranylgeranyl pyrophosphate synthase (GGPP synthase) (GGPPSase) (EC 2.5.1.-) ((2E,6E)-farnesyl diphosphate synthase) (Dimethylallyltranstransferase) (EC 2.5.1.1) (Farnesyl diphosphate synthase) (Farnesyltranstransferase) (EC 2.5.1.29) (Geranylgeranyl diphosphate synthase) (Geranyltranstransferase) (EC 2.5.1.10) Bos taurus (Bovine) farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; geranylgeranyl diphosphate biosynthetic process [GO:0033386]; isoprenoid biosynthetic process [GO:0008299]; isoprenoid metabolic process [GO:0006720] GO:0004161; GO:0004311; GO:0004337; GO:0004659; GO:0005654; GO:0005737; GO:0005829; GO:0006720; GO:0008299; GO:0030018; GO:0033384; GO:0033386; GO:0042802; GO:0045337; GO:0046872; GO:0048471 33357 XM_044311719.1 245 345 599 219 996 NA NA NA NA NA NA 33358 XR_006396328.1 2 0 0 0 62 NA NA NA NA NA NA 33359 XM_029358578.2 1145 764 356 534 585 C9J069 1.21e-29 Apical junction component 1 homolog Homo sapiens (Human) cell-cell junction organization [GO:0045216] GO:0005886; GO:0005912; GO:0005929; GO:0016324; GO:0043296; GO:0045216 33360 XM_029355517.2 47 0 38 75 111 Q8NFF2 1.17e-115 Sodium/potassium/calcium exchanger 4 (Na(+)/K(+)/Ca(2+)-exchange protein 4) (Solute carrier family 24 member 4) Homo sapiens (Human) amelogenesis [GO:0097186]; calcium ion export across plasma membrane [GO:1990034]; calcium ion homeostasis [GO:0055074]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; cellular response to high light intensity [GO:0071486]; cone photoresponse recovery [GO:0036368]; detection of chemical stimulus involved in sensory perception of smell [GO:0050911]; drinking behavior [GO:0042756]; enamel mineralization [GO:0070166]; ion transport [GO:0006811]; membrane repolarization [GO:0086009]; negative regulation of calcium-mediated signaling [GO:0050849]; olfactory nerve maturation [GO:0021630]; phototransduction [GO:0007602]; positive regulation of gene expression [GO:0010628]; potassium ion transmembrane transport [GO:0071805]; regulation of eating behavior [GO:1903998]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; regulation of signaling receptor activity [GO:0010469]; response to high light intensity [GO:0009644]; response to melanocyte-stimulating hormone [GO:1990680]; response to odorant [GO:1990834]; sensory perception of smell [GO:0007608]; sodium ion transmembrane transport [GO:0035725] GO:0005262; GO:0005516; GO:0005737; GO:0005886; GO:0006811; GO:0006874; GO:0007602; GO:0007608; GO:0008273; GO:0008277; GO:0009644; GO:0010469; GO:0010628; GO:0015293; GO:0016020; GO:0016324; GO:0021630; GO:0031982; GO:0035725; GO:0036368; GO:0042756; GO:0048306; GO:0050849; GO:0050911; GO:0055074; GO:0070166; GO:0070588; GO:0071486; GO:0071805; GO:0086009; GO:0097186; GO:0098703; GO:0120199; GO:1903998; GO:1990034; GO:1990680; GO:1990834 33361 XR_006397266.1 4 0 17 23 0 NA NA NA NA NA NA 33362 XM_044315165.1 29 58 79 263 3 NA NA NA NA NA NA 33363 XM_044308291.1 198 152 109 237 234 NA NA NA NA NA NA 33364 XM_029352095.2 2 0 7 0 30 Q8R4V5 4.35e-40 Oncoprotein-induced transcript 3 protein (Liver-specific zona pellucida domain-containing protein) Mus musculus (Mouse) urate homeostasis [GO:1903118] GO:0005201; GO:0005509; GO:0005615; GO:0005635; GO:0009986; GO:1903118 33365 XM_029332378.2 34 1 25 29 73 NA NA NA NA NA NA 33366 XM_044321507.1 0 0 30 0 0 NA NA NA NA NA NA 33367 XM_044313800.1 417 271 456 166 577 Q7RTR2 1.05e-72 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 33368 XM_044313800.1 417 271 456 166 577 Q7RTR2 1.65e-66 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 33369 XM_044313800.1 417 271 456 166 577 Q7RTR2 7.73e-66 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 33370 XM_044313800.1 417 271 456 166 577 Q7RTR2 5.01e-63 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 33371 XM_044313800.1 417 271 456 166 577 Q7RTR2 5.28e-55 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 33372 XM_029330244.2 3883 3049 3197 3045 4284 NA NA NA NA NA NA 33373 XR_006394785.1 0 0 0 0 6 NA NA NA NA NA NA 33374 XM_044321834.1 948 469 481 616 717 NA NA NA NA NA NA 33375 XM_029331339.2 281 174 9 24 163 O43246 1.66e-124 Cationic amino acid transporter 4 (CAT-4) (CAT4) (Solute carrier family 7 member 4) Homo sapiens (Human) amino acid transport [GO:0006865] GO:0005886; GO:0006865; GO:0015171; GO:0015174; GO:0016020 33376 XM_029323886.2 47 44 49 171 85 F1RB95 4.72e-135 NA NA NA NA 33377 XR_003824185.2 65 34 52 37 33 Q8TF09 8.74e-32 Dynein light chain roadblock-type 2 (Dynein light chain 2B, cytoplasmic) (Roadblock domain-containing protein 2) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0003777; GO:0005737; GO:0005813; GO:0005868; GO:0005874; GO:0005929; GO:0007018; GO:0045505; GO:0097542 33378 XM_029348425.2 41 0 13 22 39 Q9H4G4 3.32e-28 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Homo sapiens (Human) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070062; GO:0070374 33379 XM_029351613.2 667 283 176 366 367 Q5W041 1.72e-160 Armadillo repeat-containing protein 3 (Beta-catenin-like protein) (Cancer/testis antigen 81) (CT81) (KU-CT-1) Homo sapiens (Human) NA GO:0070062 33380 XM_029351613.2 667 283 176 366 367 Q5W041 6.3e-43 Armadillo repeat-containing protein 3 (Beta-catenin-like protein) (Cancer/testis antigen 81) (CT81) (KU-CT-1) Homo sapiens (Human) NA GO:0070062 33381 XM_029347279.2 258 451 153 333 178 NA NA NA NA NA NA 33382 XM_029348945.2 93 34 421 87 807 O54852 3.39e-102 Potassium voltage-gated channel subfamily H member 7 (Ether-a-go-go-related gene potassium channel 3) (ERG-3) (Eag-related protein 3) (Ether-a-go-go-related protein 3) (Voltage-gated potassium channel subunit Kv11.3) Rattus norvegicus (Rat) circadian rhythm [GO:0007623]; membrane repolarization during action potential [GO:0086011]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391] GO:0005242; GO:0005249; GO:0005267; GO:0005886; GO:0006813; GO:0007623; GO:0034765; GO:0042391; GO:0044877; GO:0071805; GO:0086011 33383 XR_006392020.1 64 43 5 23 58 NA NA NA NA NA NA 33384 XM_029329914.2 37 15 41 33 132 B8VIU6 1.36e-127 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 33385 XM_044325739.1 281 289 157 422 595 Q9JJS0 1.81e-38 Signal peptide, CUB and EGF-like domain-containing protein 2 (Protein CEGP1) (Scube/You) Mus musculus (Mouse) chondrocyte differentiation involved in endochondral bone morphogenesis [GO:0003413]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of ossification [GO:0045778]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of smoothened signaling pathway [GO:0045880]; signal transduction [GO:0007165] GO:0003413; GO:0005509; GO:0005615; GO:0007165; GO:0008289; GO:0009986; GO:0019897; GO:0042802; GO:0045669; GO:0045778; GO:0045880; GO:0097108; GO:1902732 33386 XM_029341884.2 1259 1007 629 1095 1185 NA NA NA NA NA NA 33387 XM_044327764.1 49 17 36 49 73 NA NA NA NA NA NA 33388 XR_003827976.2 3 0 14 0 0 NA NA NA NA NA NA 33389 XR_006393915.1 41 2 25 5 151 NA NA NA NA NA NA 33390 XR_006391849.1 18 26 6 1 26 NA NA NA NA NA NA 33391 XR_006397033.1 68 71 18 47 18 NA NA NA NA NA NA 33392 XM_029337263.2 344 124 302 340 416 Q6JZS3 7.97e-73 Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) Oryzias latipes (Japanese rice fish) (Japanese killifish) NA GO:0004497; GO:0005506; GO:0005789; GO:0020037; GO:0043231; GO:0070330 33393 XR_006391384.1 62 13 25 30 39 NA NA NA NA NA NA 33394 XM_044313273.1 14 13 19 0 0 NA NA NA NA NA NA 33395 XM_029333881.2 49 0 12 39 206 P34949 3.03e-136 Mannose-6-phosphate isomerase (EC 5.3.1.8) (Phosphohexomutase) (Phosphomannose isomerase) (PMI) Homo sapiens (Human) GDP-mannose biosynthetic process [GO:0009298]; mannose to fructose-6-phosphate metabolic process [GO:0061611] GO:0004476; GO:0005829; GO:0008270; GO:0009298; GO:0061611; GO:0070062 33396 XM_029344501.2 3353 849 572 2666 3538 A0A2P1BRQ0 3.67e-82 Cytolytic toxin-alpha (Sp-CTx-alpha) Scorpaena plumieri (Spotted scorpionfish) hemolysis in another organism [GO:0044179] GO:0005576; GO:0044179; GO:0090729 33397 XM_029335399.2 14 104 26 35 3 NA NA NA NA NA NA 33398 XR_006392708.1 43 9 4 8 7 NA NA NA NA NA NA 33399 XM_029336345.2 111 77 108 107 94 NA NA NA NA NA NA 33400 XM_044321710.1 0 0 22 0 1 A4D0V7 4.42e-101 Cadherin-like and PC-esterase domain-containing protein 1 Homo sapiens (Human) NA GO:0005783 33401 XM_029355913.2 531 126 190 509 542 C9D7C2 0 Voltage-dependent calcium channel type A subunit alpha-1 (Cacophony protein) Apis mellifera (Honeybee) regulation of ion transmembrane transport [GO:0034765] GO:0005245; GO:0005509; GO:0005891; GO:0034765 33402 XR_006393150.1 0 16 16 11 16 NA NA NA NA NA NA 33403 XM_044307733.1 190 337 144 312 246 NA NA NA NA NA NA 33404 XM_029327971.2 9 17 0 2 5 NA NA NA NA NA NA 33405 XM_029342057.2 357 153 205 239 246 NA NA NA NA NA NA 33406 XM_029337795.2 0 71 226 858 99 B3EWY9 5.88e-28 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 33407 XM_029337795.2 0 71 226 858 99 B3EWY9 8.24e-24 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 33408 XM_029333517.2 2103 1514 1201 2423 1902 Q6GN29 0 Atlastin-2 (EC 3.6.5.-) (ADP-ribosylation factor-like protein 6-interacting protein 2) (ARL-6-interacting protein 2) (Aip-2) Xenopus laevis (African clawed frog) endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum tubular network membrane organization [GO:1990809]; Golgi organization [GO:0007030]; protein homooligomerization [GO:0051260] GO:0003924; GO:0005525; GO:0005783; GO:0007029; GO:0007030; GO:0016020; GO:0042802; GO:0051260; GO:0098826; GO:1990809 33409 XR_003825444.2 33 40 35 16 35 NA NA NA NA NA NA 33410 XM_044325710.1 0 0 0 0 6 NA NA NA NA NA NA 33411 XR_003824614.2 0 0 0 0 14 NA NA NA NA NA NA 33412 XM_029332903.2 0 284 37 0 95 NA NA NA NA NA NA 33413 XM_044317584.1 21 12 20 5 20 B8VIU6 6.5e-23 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 33414 XM_044318030.1 2 0 0 10 0 NA NA NA NA NA NA 33415 XM_044325322.1 238 226 179 247 465 A6QLU6 2.01e-70 Adhesion G-protein coupled receptor D1 (G-protein coupled receptor 133) Bos taurus (Bovine) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0005886; GO:0007166; GO:0007186; GO:0007189 33416 XM_044318724.1 335 271 114 675 134 NA NA NA NA NA NA 33417 XM_029327039.2 48 0 0 20 0 P81139 3.01e-56 Pancreatic lipase-related protein 2 (PL-RP2) (Cytotoxic T lymphocyte lipase) (GPL) (Galactolipase) (EC 3.1.1.26) (Triacylglycerol lipase) (EC 3.1.1.3) Cavia porcellus (Guinea pig) galactolipid catabolic process [GO:0019376]; lipid metabolic process [GO:0006629]; phospholipid catabolic process [GO:0009395]; phospholipid metabolic process [GO:0006644]; triglyceride catabolic process [GO:0019433] GO:0004620; GO:0004806; GO:0005509; GO:0005615; GO:0006629; GO:0006644; GO:0009395; GO:0016020; GO:0019376; GO:0019433; GO:0031410; GO:0043005; GO:0047372; GO:0047714; GO:0102549 33418 XM_044324289.1 21 0 64 18 32 Q76IC6 2.6e-28 Palmitoyltransferase ZDHHC23 (EC 2.3.1.225) (NNOS-interacting DHHC domain-containing protein with dendritic mRNA) (Zinc finger DHHC domain-containing protein 23) (DHHC-23) (zDHHC23) Rattus norvegicus (Rat) peptidyl-L-cysteine S-palmitoylation [GO:0018230]; protein localization to plasma membrane [GO:0072659]; protein palmitoylation [GO:0018345]; protein targeting to membrane [GO:0006612] GO:0000139; GO:0005783; GO:0005794; GO:0006612; GO:0018230; GO:0018345; GO:0019706; GO:0072659 33419 XM_029344061.2 15 117 39 137 64 NA NA NA NA NA NA 33420 XR_006395745.1 56 33 40 63 110 NA NA NA NA NA NA 33421 XM_044322519.1 79 30 0 63 53 NA NA NA NA NA NA 33422 XM_029346025.2 61 24 41 13 14 Q68CR1 9.23e-90 Protein sel-1 homolog 3 (Suppressor of lin-12-like protein 3) (Sel-1L3) Homo sapiens (Human) NA GO:0005654; GO:0016020 33423 XM_044316009.1 14 2 12 2 18 Q5ZMW0 1.54e-118 Protein argonaute-4 (Argonaute4) (Argonaute RISC catalytic component 4) (Eukaryotic translation initiation factor 2C 4) (eIF-2C 4) (eIF2C 4) Gallus gallus (Chicken) miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; mRNA catabolic process [GO:0006402] GO:0000932; GO:0003723; GO:0003727; GO:0004521; GO:0006402; GO:0016442; GO:0035198; GO:0035278 33424 XM_029338009.2 0 0 13 0 27 NA NA NA NA NA NA 33425 XM_029330582.2 1331 1532 854 1498 1696 Q8CG46 0 Structural maintenance of chromosomes protein 5 (SMC protein 5) (SMC-5) (mSMC5) (Protein expressed in male leptotene and zygotene spermatocytes 453) (MLZ-453) Mus musculus (Mouse) cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; cellular senescence [GO:0090398]; chromosome condensation [GO:0030261]; chromosome segregation [GO:0007059]; double-strand break repair via homologous recombination [GO:0000724]; internal peptidyl-lysine acetylation [GO:0018393]; mitotic cell cycle phase transition [GO:0044772]; positive regulation of chromosome segregation [GO:0051984]; positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184]; protein localization to chromosome, centromeric region [GO:0071459]; stem cell population maintenance [GO:0019827]; telomere maintenance via recombination [GO:0000722] GO:0000722; GO:0000724; GO:0000775; GO:0000781; GO:0000803; GO:0003697; GO:0005524; GO:0005634; GO:0005737; GO:0006974; GO:0007059; GO:0016605; GO:0016607; GO:0016887; GO:0018393; GO:0019827; GO:0030054; GO:0030261; GO:0030915; GO:0034184; GO:0035061; GO:0035861; GO:0044772; GO:0051301; GO:0051984; GO:0071459; GO:0090398 33426 XM_044309468.1 6852 6106 5140 6487 5122 P37193 6.79e-69 Adrenodoxin-like protein 1, mitochondrial (Ferredoxin-1) Drosophila melanogaster (Fruit fly) electron transport chain [GO:0022900]; P450-containing electron transport chain [GO:0140647]; positive regulation of ecdysteroid biosynthetic process [GO:0045998]; positive regulation of oxidoreductase activity [GO:0051353]; steroid biosynthetic process [GO:0006694] GO:0005739; GO:0005759; GO:0006694; GO:0009055; GO:0022900; GO:0045998; GO:0046872; GO:0051353; GO:0051537; GO:0140647 33427 XM_029337000.2 0 0 0 88 0 Q5RHR6 0 Protein broad-minded (TBC1 domain family member 32) Danio rerio (Zebrafish) (Brachydanio rerio) axoneme assembly [GO:0035082]; cilium assembly [GO:0060271]; non-motile cilium assembly [GO:1905515] GO:0005737; GO:0005929; GO:0035082; GO:0060271; GO:1905515 33428 XM_029348855.2 2397 2270 2016 2830 3346 O75081 1.45e-131 Protein CBFA2T3 (MTG8-related protein 2) (Myeloid translocation gene on chromosome 16 protein) (hMTG16) (Zinc finger MYND domain-containing protein 4) Homo sapiens (Human) granulocyte differentiation [GO:0030851]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of glycolytic process [GO:0045820]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; regulation of aerobic respiration [GO:1903715]; response to hypoxia [GO:0001666] GO:0000139; GO:0001666; GO:0003714; GO:0005634; GO:0005654; GO:0005730; GO:0008285; GO:0030851; GO:0032436; GO:0045820; GO:0045892; GO:0046872; GO:1903715 33429 XM_029356431.2 107 55 66 86 151 Q9MYM7 6.58e-27 Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.86) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1) Pongo pygmaeus (Bornean orangutan) lipid metabolic process [GO:0006629]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0006629; GO:0047275 33430 XM_044323674.1 0 65 54 3 115 NA NA NA NA NA NA 33431 XM_044325993.1 328 27 215 143 345 NA NA NA NA NA NA 33432 XM_044316395.1 60 120 182 451 192 P21328 1.95e-25 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 33433 XM_029355619.2 17 0 19 73 31 NA NA NA NA NA NA 33434 XM_029335388.2 18 13 13 21 10 NA NA NA NA NA NA 33435 XR_006397887.1 1391 1033 524 961 917 A0A1B0GTJ6 8.21e-24 NA NA NA NA 33436 XM_029350957.2 211 245 162 278 219 NA NA NA NA NA NA 33437 XM_044318810.1 332 37 151 160 240 B3EWY9 0 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 33438 XM_044318810.1 332 37 151 160 240 B3EWY9 0 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 33439 XM_044318810.1 332 37 151 160 240 B3EWY9 1.39e-34 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 33440 XR_006391304.1 88 79 139 105 119 NA NA NA NA NA NA 33441 XM_029341615.2 27 170 0 221 530 Q5PRF9 1.39e-73 Protein Smaug homolog 2 (Smaug 2) (hSmaug2) (Sterile alpha motif domain-containing protein 4B) (SAM domain-containing protein 4B) Homo sapiens (Human) nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289] GO:0000289; GO:0000932; GO:0003723; GO:0003729; GO:0005634; GO:0005829; GO:0030371 33442 XM_029335272.2 1145 928 664 945 822 Q5R6Q7 1.2e-31 Sorting nexin-16 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; protein targeting to lysosome [GO:0006622] GO:0005764; GO:0005769; GO:0005770; GO:0005829; GO:0006622; GO:0008333; GO:0031313; GO:0031901; GO:0031902; GO:0035091; GO:0045022 33443 XM_044312184.1 10 16 84 74 106 NA NA NA NA NA NA 33444 XM_044316898.1 70 6 35 14 25 NA NA NA NA NA NA 33445 XM_029348397.2 59 455 77 109 139 Q9JJS6 7.27e-106 Beta,beta-carotene 15,15'-dioxygenase (EC 1.13.11.63) (Beta-carotene dioxygenase 1) (Beta-carotene oxygenase 1) Mus musculus (Mouse) beta-carotene metabolic process [GO:1901810]; carotene catabolic process [GO:0016121]; retinal metabolic process [GO:0042574]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572] GO:0001523; GO:0003834; GO:0005829; GO:0010436; GO:0016121; GO:0042572; GO:0042574; GO:0046872; GO:1901810 33446 XM_044323618.1 14 0 2 0 0 NA NA NA NA NA NA 33447 XR_006395977.1 19 39 43 118 87 NA NA NA NA NA NA 33448 XR_006397772.1 1183 1058 432 1035 842 NA NA NA NA NA NA 33449 XM_029338550.2 80 101 64 98 167 NA NA NA NA NA NA 33450 XM_029340595.2 218 193 113 221 256 NA NA NA NA NA NA 33451 XR_006393402.1 5 14 0 0 0 NA NA NA NA NA NA 33452 XM_044322725.1 157 152 180 168 198 P09759 7.46e-172 Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (Tyrosine-protein kinase receptor EPH-2) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; axon guidance [GO:0007411]; camera-type eye morphogenesis [GO:0048593]; cell chemotaxis [GO:0060326]; cell-substrate adhesion [GO:0031589]; central nervous system projection neuron axonogenesis [GO:0021952]; cranial nerve development [GO:0021545]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; ephrin receptor signaling pathway [GO:0048013]; establishment of cell polarity [GO:0030010]; hindbrain tangential cell migration [GO:0021934]; immunological synapse formation [GO:0001771]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of satellite cell differentiation [GO:1902725]; negative regulation of skeletal muscle satellite cell proliferation [GO:1902723]; neural precursor cell proliferation [GO:0061351]; neurogenesis [GO:0022008]; optic nerve morphogenesis [GO:0021631]; positive regulation of kinase activity [GO:0033674]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of neuron death [GO:1901214]; retinal ganglion cell axon guidance [GO:0031290]; skeletal muscle satellite cell activation [GO:0014719]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0001525; GO:0001771; GO:0004713; GO:0004714; GO:0005005; GO:0005524; GO:0005737; GO:0005783; GO:0005829; GO:0005886; GO:0007169; GO:0007411; GO:0008046; GO:0014719; GO:0016020; GO:0021545; GO:0021631; GO:0021934; GO:0021952; GO:0022008; GO:0030010; GO:0030424; GO:0030425; GO:0031290; GO:0031589; GO:0031901; GO:0032433; GO:0033674; GO:0043005; GO:0043235; GO:0044877; GO:0045121; GO:0046328; GO:0046777; GO:0048013; GO:0048593; GO:0050804; GO:0050965; GO:0051965; GO:0060326; GO:0060996; GO:0060997; GO:0061351; GO:0070372; GO:0098978; GO:1901214; GO:1902723; GO:1902725 33453 XM_044314951.1 305 174 234 366 359 O94887 1.4e-50 FERM, ARHGEF and pleckstrin domain-containing protein 2 (FERM domain-including RhoGEF) (FIR) (FERM, RhoGEF and pleckstrin domain-containing protein 2) (Pleckstrin homology domain-containing family C member 3) (PH domain-containing family C member 3) Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; cell adhesion [GO:0007155]; hair cycle process [GO:0022405]; neuron remodeling [GO:0016322]; osteoclast differentiation [GO:0030316]; podosome assembly [GO:0071800]; Rac protein signal transduction [GO:0016601]; regulation of integrin activation [GO:0033623]; semaphorin-plexin signaling pathway [GO:0071526] GO:0005085; GO:0005737; GO:0005829; GO:0005856; GO:0007155; GO:0008092; GO:0016322; GO:0016601; GO:0022405; GO:0030316; GO:0031532; GO:0033623; GO:0071526; GO:0071800 33454 XM_029328872.2 257 263 154 50 149 Q28DB0 1.37e-159 Tetratricopeptide repeat protein 39B (TPR repeat protein 39B) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) lipid metabolic process [GO:0006629] GO:0006629 33455 XM_044324778.1 52 24 53 129 77 NA NA NA NA NA NA 33456 XM_029330433.2 1089 1259 1234 1291 1370 D0Z9R0 2.16e-61 3'-5' ssDNA/RNA exonuclease TatD (EC 3.1.11.-) (EC 3.1.13.-) (DNase TatD) Edwardsiella tarda (strain EIB202) NA GO:0000175; GO:0000287; GO:0005737; GO:0008310 33457 XM_044321976.1 1038 1340 1061 1329 1051 Q0EEE2 3.04e-76 Patched domain-containing protein 3 (RND-type protein RNDEu-3) Mus musculus (Mouse) NA GO:0005783; GO:0005789; GO:0005886; GO:0016020; GO:0097225 33458 XM_044326466.1 0 1 2 25 13 Q92611 0 ER degradation-enhancing alpha-mannosidase-like protein 1 Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; endoplasmic reticulum mannose trimming [GO:1904380]; mannose trimming involved in glycoprotein ERAD pathway [GO:1904382]; positive regulation of retrograde protein transport, ER to cytosol [GO:1904154]; protein targeting to ER [GO:0045047]; response to unfolded protein [GO:0006986]; trimming of terminal mannose on C branch [GO:0036510]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent glycoprotein ERAD pathway [GO:0097466] GO:0004571; GO:0005509; GO:0005783; GO:0005789; GO:0005975; GO:0006986; GO:0016235; GO:0030433; GO:0036510; GO:0044322; GO:0045047; GO:0051787; GO:0097466; GO:1904154; GO:1904380; GO:1904382 33459 XM_029335887.2 763 839 523 692 673 Q9Y6N1 3.12e-85 Cytochrome c oxidase assembly protein COX11, mitochondrial Homo sapiens (Human) metal ion homeostasis [GO:0055065]; negative regulation of glucokinase activity [GO:0033132] GO:0005507; GO:0005739; GO:0005743; GO:0009055; GO:0032991; GO:0033132; GO:0055065 33460 XM_044314066.1 0 0 2 17 0 NA NA NA NA NA NA 33461 XM_029358056.2 271 286 242 321 408 Q28BZ2 5.16e-36 Adenosine 5'-monophosphoramidase HINT3 (EC 3.9.1.-) (Histidine triad nucleotide-binding protein 3) (HINT-3) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0000166; GO:0005634; GO:0005737; GO:0043530 33462 XM_044316693.1 28 0 0 34 10 NA NA NA NA NA NA 33463 XM_029343589.2 85 64 63 78 124 NA NA NA NA NA NA 33464 XM_044313902.1 97 66 25 0 22 NA NA NA NA NA NA 33465 XR_006395186.1 11 13 37 0 13 NA NA NA NA NA NA 33466 XM_029346424.2 636 534 439 649 706 A1L258 0 D-2-hydroxyglutarate dehydrogenase, mitochondrial (EC 1.1.99.39) Danio rerio (Zebrafish) (Brachydanio rerio) malate metabolic process [GO:0006108] GO:0005739; GO:0006108; GO:0008270; GO:0051990; GO:0071949 33467 XM_044315259.1 301 418 328 342 444 Q7RTR2 4.35e-53 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 33468 XM_044315259.1 301 418 328 342 444 Q7RTR2 1.2e-52 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 33469 XM_044315259.1 301 418 328 342 444 Q7RTR2 2.28e-44 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 33470 XR_006397410.1 4 0 26 29 60 NA NA NA NA NA NA 33471 XM_044325143.1 3248 3781 2193 2882 1446 A6QQM4 1.02e-55 Zinc finger protein 474 Bos taurus (Bovine) NA GO:0046872 33472 XM_044325143.1 3248 3781 2193 2882 1446 A6QQM4 1.09e-34 Zinc finger protein 474 Bos taurus (Bovine) NA GO:0046872 33473 XM_029343394.2 785 1043 410 1343 644 Q6GL75 3.97e-91 Sister chromatid cohesion protein DCC1 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) DNA replication [GO:0006260]; maintenance of mitotic sister chromatid cohesion [GO:0034088]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0003677; GO:0006260; GO:0006275; GO:0031390; GO:0034088 33474 XM_029348775.2 5 7 26 26 51 Q20191 1.98e-44 Zinc metalloproteinase nas-13 (EC 3.4.24.-) (Nematode astacin 13) Caenorhabditis elegans proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0006508; GO:0008270 33475 XM_044315633.1 68 236 171 10 89 NA NA NA NA NA NA 33476 XM_029337582.2 26 12 6 22 26 NA NA NA NA NA NA 33477 XM_029325957.2 375 213 124 225 213 Q8INF0 7.93e-153 Soluble guanylate cyclase 88E (EC 4.6.1.2) Drosophila melanogaster (Fruit fly) cGMP-mediated signaling [GO:0019934]; nitric oxide-cGMP-mediated signaling pathway [GO:0038060]; response to hypoxia [GO:0001666]; response to oxygen levels [GO:0070482]; response to reactive oxygen species [GO:0000302] GO:0000302; GO:0001666; GO:0003924; GO:0004383; GO:0005525; GO:0008074; GO:0019825; GO:0019826; GO:0019899; GO:0019934; GO:0020037; GO:0038060; GO:0042803; GO:0046872; GO:0046982; GO:0070025; GO:0070026; GO:0070482 33478 XM_029338196.2 0 0 10 0 33 NA NA NA NA NA NA 33479 XR_006394935.1 29 98 0 95 329 NA NA NA NA NA NA 33480 XM_044307833.1 2495 2125 1064 1665 1202 NA NA NA NA NA NA 33481 XM_044313647.1 0 6 0 0 0 C3VPR6 7.12e-26 Protein NLRC5 Mus musculus (Mouse) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of type II interferon-mediated signaling pathway [GO:0060335]; regulation of kinase activity [GO:0043549]; response to bacterium [GO:0009617] GO:0000978; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0009617; GO:0032088; GO:0035556; GO:0043549; GO:0045087; GO:0045345; GO:0045944; GO:0051607; GO:0060335; GO:0060339; GO:0060340 33482 XM_044327760.1 5 3 7 8 71 NA NA NA NA NA NA 33483 XR_006396756.1 2 3 112 22 198 NA NA NA NA NA NA 33484 XM_044328678.1 70 227 0 0 354 NA NA NA NA NA NA 33485 XM_044307828.1 9 0 9 4 2 NA NA NA NA NA NA 33486 XM_044325758.1 72 42 0 20 35 Q9JK72 2.51e-67 Copper chaperone for superoxide dismutase (Superoxide dismutase copper chaperone) Rattus norvegicus (Rat) positive regulation of oxidoreductase activity [GO:0051353]; removal of superoxide radicals [GO:0019430] GO:0005507; GO:0005634; GO:0005737; GO:0016532; GO:0019430; GO:0019899; GO:0051353 33487 XM_044322965.1 705 536 506 643 799 Q0V9W6 4.61e-102 BTB/POZ domain-containing protein 6 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737 33488 XM_044307047.1 34 905 755 0 1067 O75445 5.54e-115 Usherin (Usher syndrome type IIa protein) (Usher syndrome type-2A protein) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear receptor cell differentiation [GO:0060113]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0001917; GO:0002141; GO:0002142; GO:0005518; GO:0005576; GO:0005604; GO:0005737; GO:0007601; GO:0007605; GO:0009887; GO:0009888; GO:0016324; GO:0016477; GO:0017022; GO:0032391; GO:0032421; GO:0034446; GO:0035315; GO:0036064; GO:0042491; GO:0042802; GO:0045184; GO:0045494; GO:0048496; GO:0050896; GO:0050953; GO:0051649; GO:0060113; GO:0060171; GO:1990075; GO:1990696 33489 XM_044318489.1 38 6 33 41 118 NA NA NA NA NA NA 33490 XM_044321168.1 1 0 0 15 35 NA NA NA NA NA NA 33491 XM_029351651.2 0 532 273 847 706 NA NA NA NA NA NA 33492 XM_029333722.2 613 349 345 589 504 Q8TBZ3 0 WD repeat-containing protein 20 (Protein DMR) Homo sapiens (Human) NA GO:0005654 33493 XM_029343232.2 1582 651 882 2464 2102 Q8BIE6 1.16e-135 FERM domain-containing protein 4A Mus musculus (Mouse) establishment of epithelial cell polarity [GO:0090162]; negative regulation of protein secretion [GO:0050709]; positive regulation of protein secretion [GO:0050714] GO:0005737; GO:0005856; GO:0005912; GO:0005923; GO:0030674; GO:0050709; GO:0050714; GO:0090162 33494 XM_044323642.1 0 7 0 33 0 NA NA NA NA NA NA 33495 XM_044326067.1 209 121 78 176 178 Q9WVQ1 1.56e-154 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Activin receptor-interacting protein 1) (Acvrip1) (Atrophin-1-interacting protein 1) (AIP-1) (Membrane-associated guanylate kinase inverted 2) (MAGI-2) Mus musculus (Mouse) cellular response to nerve growth factor stimulus [GO:1990090]; clathrin-dependent endocytosis [GO:0072583]; negative regulation of activin receptor signaling pathway [GO:0032926]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein kinase B signaling [GO:0051898]; nerve growth factor signaling pathway [GO:0038180]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; podocyte development [GO:0072015]; positive regulation of neuron projection development [GO:0010976]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of receptor internalization [GO:0002092]; positive regulation of synaptic vesicle clustering [GO:2000809]; receptor clustering [GO:0043113]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of synaptic membrane adhesion [GO:0099179]; signal transduction [GO:0007165]; SMAD protein signal transduction [GO:0060395] GO:0001750; GO:0001917; GO:0002092; GO:0005634; GO:0005737; GO:0005770; GO:0005814; GO:0005886; GO:0005911; GO:0005923; GO:0007165; GO:0008285; GO:0010976; GO:0014069; GO:0019894; GO:0019902; GO:0030159; GO:0030336; GO:0030425; GO:0031697; GO:0032516; GO:0032926; GO:0032991; GO:0036057; GO:0038180; GO:0043113; GO:0044877; GO:0045202; GO:0046332; GO:0048471; GO:0051898; GO:0060395; GO:0070697; GO:0070699; GO:0072015; GO:0072583; GO:0097118; GO:0097546; GO:0098696; GO:0098879; GO:0098890; GO:0098919; GO:0098978; GO:0098982; GO:0099179; GO:1990090; GO:2000809 33496 XM_044326067.1 209 121 78 176 178 Q9WVQ1 7.4e-46 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Activin receptor-interacting protein 1) (Acvrip1) (Atrophin-1-interacting protein 1) (AIP-1) (Membrane-associated guanylate kinase inverted 2) (MAGI-2) Mus musculus (Mouse) cellular response to nerve growth factor stimulus [GO:1990090]; clathrin-dependent endocytosis [GO:0072583]; negative regulation of activin receptor signaling pathway [GO:0032926]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein kinase B signaling [GO:0051898]; nerve growth factor signaling pathway [GO:0038180]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; podocyte development [GO:0072015]; positive regulation of neuron projection development [GO:0010976]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of receptor internalization [GO:0002092]; positive regulation of synaptic vesicle clustering [GO:2000809]; receptor clustering [GO:0043113]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of synaptic membrane adhesion [GO:0099179]; signal transduction [GO:0007165]; SMAD protein signal transduction [GO:0060395] GO:0001750; GO:0001917; GO:0002092; GO:0005634; GO:0005737; GO:0005770; GO:0005814; GO:0005886; GO:0005911; GO:0005923; GO:0007165; GO:0008285; GO:0010976; GO:0014069; GO:0019894; GO:0019902; GO:0030159; GO:0030336; GO:0030425; GO:0031697; GO:0032516; GO:0032926; GO:0032991; GO:0036057; GO:0038180; GO:0043113; GO:0044877; GO:0045202; GO:0046332; GO:0048471; GO:0051898; GO:0060395; GO:0070697; GO:0070699; GO:0072015; GO:0072583; GO:0097118; GO:0097546; GO:0098696; GO:0098879; GO:0098890; GO:0098919; GO:0098978; GO:0098982; GO:0099179; GO:1990090; GO:2000809 33497 XM_044323865.1 19 0 30 13 12 NA NA NA NA NA NA 33498 XR_006396374.1 30 25 38 76 55 NA NA NA NA NA NA 33499 XM_029329007.2 17 1 27 0 0 Q8BG58 1.69e-73 Transmembrane prolyl 4-hydroxylase (P4H-TM) (EC 1.14.11.29) (Hypoxia-inducible factor prolyl hydroxylase 4) (HIF-PH4) (HIF-prolyl hydroxylase 4) (HPH-4) Mus musculus (Mouse) peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; regulation of erythrocyte differentiation [GO:0045646] GO:0004656; GO:0005506; GO:0005509; GO:0005783; GO:0005789; GO:0016706; GO:0018401; GO:0031418; GO:0045646 33500 XR_006396943.1 0 0 0 1 19 NA NA NA NA NA NA 33501 XM_029355229.2 369 234 238 326 374 Q5RA91 1.07e-48 Transcription initiation factor TFIID subunit 11 (TFIID subunit p30-beta) (Transcription initiation factor TFIID 28 kDa subunit) (TAF(II)28) (TAFII-28) (TAFII28) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) RNA polymerase II preinitiation complex assembly [GO:0051123] GO:0005669; GO:0046982; GO:0051123 33502 XM_044327165.1 915 1063 749 817 949 P46461 0 Vesicle-fusing ATPase 1 (EC 3.6.4.6) (N-ethylmaleimide-sensitive fusion protein 1) (NEM-sensitive fusion protein 1) (Protein comatose) (Vesicular-fusion protein NSF1) (dNsf-1) (NSF-1) Drosophila melanogaster (Fruit fly) autophagy [GO:0006914]; Golgi organization [GO:0007030]; Golgi to lysosome transport [GO:0090160]; Golgi to plasma membrane protein transport [GO:0043001]; intra-Golgi vesicle-mediated transport [GO:0006891]; neuromuscular synaptic transmission [GO:0007274]; neuron cellular homeostasis [GO:0070050]; neurotransmitter secretion [GO:0007269]; regulation of neuromuscular synaptic transmission [GO:1900073]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; SNARE complex disassembly [GO:0035494]; synaptic vesicle cycle [GO:0099504]; synaptic vesicle fusion to presynaptic active zone membrane [GO:0031629]; synaptic vesicle priming [GO:0016082] GO:0005524; GO:0005737; GO:0005795; GO:0006891; GO:0006914; GO:0007030; GO:0007269; GO:0007274; GO:0016082; GO:0016887; GO:0031594; GO:0031629; GO:0035494; GO:0043001; GO:0043195; GO:0046872; GO:0048172; GO:0070050; GO:0090160; GO:0098527; GO:0099504; GO:0099523; GO:1900073 33503 XM_044313101.1 207 6 2 2338 5 NA NA NA NA NA NA 33504 XM_044318606.1 274 996 266 372 79 NA NA NA NA NA NA 33505 XR_006395005.1 174 58 85 142 155 Q95SX7 4.69e-30 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 33506 XR_006395005.1 174 58 85 142 155 Q95SX7 4.69e-30 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 33507 XM_044326014.1 2631 2142 1643 3085 2207 Q01484 0 Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin) Homo sapiens (Human) atrial cardiac muscle cell action potential [GO:0086014]; atrial cardiac muscle cell to AV node cell communication [GO:0086066]; atrial septum development [GO:0003283]; cellular calcium ion homeostasis [GO:0006874]; endocytosis [GO:0006897]; membrane depolarization during SA node cell action potential [GO:0086046]; paranodal junction assembly [GO:0030913]; positive regulation of calcium ion transmembrane transporter activity [GO:1901021]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cation channel activity [GO:2001259]; positive regulation of gene expression [GO:0010628]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to endoplasmic reticulum [GO:0070972]; protein localization to M-band [GO:0036309]; protein localization to organelle [GO:0033365]; protein localization to plasma membrane [GO:0072659]; protein localization to T-tubule [GO:0036371]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; regulation of atrial cardiac muscle cell action potential [GO:0098910]; regulation of calcium ion transmembrane transporter activity [GO:1901019]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of heart rate [GO:0002027]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of protein stability [GO:0031647]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of SA node cell action potential [GO:0098907]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; response to methylmercury [GO:0051597]; SA node cell action potential [GO:0086015]; SA node cell to atrial cardiac muscle cell communication [GO:0086070]; sarcoplasmic reticulum calcium ion transport [GO:0070296]; T-tubule organization [GO:0033292]; ventricular cardiac muscle cell action potential [GO:0086005] GO:0002027; GO:0003283; GO:0005200; GO:0005739; GO:0005764; GO:0005769; GO:0005829; GO:0005856; GO:0005886; GO:0006874; GO:0006897; GO:0008093; GO:0008104; GO:0010628; GO:0010881; GO:0010882; GO:0014704; GO:0015031; GO:0016323; GO:0016324; GO:0019899; GO:0019901; GO:0030018; GO:0030315; GO:0030507; GO:0030674; GO:0030913; GO:0031430; GO:0031647; GO:0031672; GO:0033292; GO:0033365; GO:0034394; GO:0036309; GO:0036371; GO:0042383; GO:0043005; GO:0043034; GO:0043268; GO:0044325; GO:0045121; GO:0045211; GO:0050821; GO:0051117; GO:0051279; GO:0051597; GO:0051924; GO:0051928; GO:0055037; GO:0055117; GO:0060307; GO:0070296; GO:0070972; GO:0072659; GO:0086004; GO:0086005; GO:0086014; GO:0086015; GO:0086046; GO:0086066; GO:0086070; GO:0086091; GO:0098907; GO:0098910; GO:0140031; GO:1901018; GO:1901019; GO:1901021; GO:2001259 33508 XM_044326014.1 2631 2142 1643 3085 2207 Q01484 1.2e-105 Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin) Homo sapiens (Human) atrial cardiac muscle cell action potential [GO:0086014]; atrial cardiac muscle cell to AV node cell communication [GO:0086066]; atrial septum development [GO:0003283]; cellular calcium ion homeostasis [GO:0006874]; endocytosis [GO:0006897]; membrane depolarization during SA node cell action potential [GO:0086046]; paranodal junction assembly [GO:0030913]; positive regulation of calcium ion transmembrane transporter activity [GO:1901021]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cation channel activity [GO:2001259]; positive regulation of gene expression [GO:0010628]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to endoplasmic reticulum [GO:0070972]; protein localization to M-band [GO:0036309]; protein localization to organelle [GO:0033365]; protein localization to plasma membrane [GO:0072659]; protein localization to T-tubule [GO:0036371]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; regulation of atrial cardiac muscle cell action potential [GO:0098910]; regulation of calcium ion transmembrane transporter activity [GO:1901019]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of heart rate [GO:0002027]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of protein stability [GO:0031647]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of SA node cell action potential [GO:0098907]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; response to methylmercury [GO:0051597]; SA node cell action potential [GO:0086015]; SA node cell to atrial cardiac muscle cell communication [GO:0086070]; sarcoplasmic reticulum calcium ion transport [GO:0070296]; T-tubule organization [GO:0033292]; ventricular cardiac muscle cell action potential [GO:0086005] GO:0002027; GO:0003283; GO:0005200; GO:0005739; GO:0005764; GO:0005769; GO:0005829; GO:0005856; GO:0005886; GO:0006874; GO:0006897; GO:0008093; GO:0008104; GO:0010628; GO:0010881; GO:0010882; GO:0014704; GO:0015031; GO:0016323; GO:0016324; GO:0019899; GO:0019901; GO:0030018; GO:0030315; GO:0030507; GO:0030674; GO:0030913; GO:0031430; GO:0031647; GO:0031672; GO:0033292; GO:0033365; GO:0034394; GO:0036309; GO:0036371; GO:0042383; GO:0043005; GO:0043034; GO:0043268; GO:0044325; GO:0045121; GO:0045211; GO:0050821; GO:0051117; GO:0051279; GO:0051597; GO:0051924; GO:0051928; GO:0055037; GO:0055117; GO:0060307; GO:0070296; GO:0070972; GO:0072659; GO:0086004; GO:0086005; GO:0086014; GO:0086015; GO:0086046; GO:0086066; GO:0086070; GO:0086091; GO:0098907; GO:0098910; GO:0140031; GO:1901018; GO:1901019; GO:1901021; GO:2001259 33509 XM_044326014.1 2631 2142 1643 3085 2207 Q01484 1.32e-103 Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin) Homo sapiens (Human) atrial cardiac muscle cell action potential [GO:0086014]; atrial cardiac muscle cell to AV node cell communication [GO:0086066]; atrial septum development [GO:0003283]; cellular calcium ion homeostasis [GO:0006874]; endocytosis [GO:0006897]; membrane depolarization during SA node cell action potential [GO:0086046]; paranodal junction assembly [GO:0030913]; positive regulation of calcium ion transmembrane transporter activity [GO:1901021]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cation channel activity [GO:2001259]; positive regulation of gene expression [GO:0010628]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to endoplasmic reticulum [GO:0070972]; protein localization to M-band [GO:0036309]; protein localization to organelle [GO:0033365]; protein localization to plasma membrane [GO:0072659]; protein localization to T-tubule [GO:0036371]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; regulation of atrial cardiac muscle cell action potential [GO:0098910]; regulation of calcium ion transmembrane transporter activity [GO:1901019]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of heart rate [GO:0002027]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of protein stability [GO:0031647]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of SA node cell action potential [GO:0098907]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; response to methylmercury [GO:0051597]; SA node cell action potential [GO:0086015]; SA node cell to atrial cardiac muscle cell communication [GO:0086070]; sarcoplasmic reticulum calcium ion transport [GO:0070296]; T-tubule organization [GO:0033292]; ventricular cardiac muscle cell action potential [GO:0086005] GO:0002027; GO:0003283; GO:0005200; GO:0005739; GO:0005764; GO:0005769; GO:0005829; GO:0005856; GO:0005886; GO:0006874; GO:0006897; GO:0008093; GO:0008104; GO:0010628; GO:0010881; GO:0010882; GO:0014704; GO:0015031; GO:0016323; GO:0016324; GO:0019899; GO:0019901; GO:0030018; GO:0030315; GO:0030507; GO:0030674; GO:0030913; GO:0031430; GO:0031647; GO:0031672; GO:0033292; GO:0033365; GO:0034394; GO:0036309; GO:0036371; GO:0042383; GO:0043005; GO:0043034; GO:0043268; GO:0044325; GO:0045121; GO:0045211; GO:0050821; GO:0051117; GO:0051279; GO:0051597; GO:0051924; GO:0051928; GO:0055037; GO:0055117; GO:0060307; GO:0070296; GO:0070972; GO:0072659; GO:0086004; GO:0086005; GO:0086014; GO:0086015; GO:0086046; GO:0086066; GO:0086070; GO:0086091; GO:0098907; GO:0098910; GO:0140031; GO:1901018; GO:1901019; GO:1901021; GO:2001259 33510 XM_044323041.1 0 78 0 0 0 NA NA NA NA NA NA 33511 XM_044307007.1 223 171 194 236 56 NA NA NA NA NA NA 33512 XM_044312395.1 2 4 14 3 41 NA NA NA NA NA NA 33513 XM_029325119.2 4505 3598 3277 3831 4049 Q56I99 0 Mothers against decapentaplegic homolog 5 (MAD homolog 5) (Mothers against DPP homolog 5) (SMAD family member 5) (SMAD 5) (Smad5) Gallus gallus (Chicken) anatomical structure morphogenesis [GO:0009653]; BMP signaling pathway [GO:0030509]; cell differentiation [GO:0030154]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0000978; GO:0000981; GO:0005634; GO:0005737; GO:0007179; GO:0009653; GO:0030154; GO:0030509; GO:0046872; GO:0060395; GO:0070411; GO:0071144 33514 XM_044314690.1 157 8 106 18 588 P14381 1.14e-27 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 33515 XM_044309550.1 0 39 3 2 0 NA NA NA NA NA NA 33516 XM_029330723.2 1720 1113 1116 1401 1416 Q9BUN8 3.69e-77 Derlin-1 (Degradation in endoplasmic reticulum protein 1) (DERtrin-1) (Der1-like protein 1) Homo sapiens (Human) endoplasmic reticulum unfolded protein response [GO:0030968]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; establishment of protein localization [GO:0045184]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein destabilization [GO:0031648]; response to unfolded protein [GO:0006986]; retrograde protein transport, ER to cytosol [GO:0030970]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0000839; GO:0002020; GO:0005047; GO:0005769; GO:0005770; GO:0005783; GO:0005789; GO:0006986; GO:0016020; GO:0030433; GO:0030968; GO:0030970; GO:0031398; GO:0031625; GO:0031648; GO:0032092; GO:0036502; GO:0036503; GO:0036513; GO:0038023; GO:0042288; GO:0042802; GO:0044322; GO:0044877; GO:0045184; GO:0051117; GO:0051787; GO:0071712; GO:1990381 33517 XR_006393275.1 0 7 12 1 46 NA NA NA NA NA NA 33518 XM_029358231.2 1689 1189 1107 1617 1374 Q6A070 2.54e-101 TOG array regulator of axonemal microtubules protein 1 (Crescerin-1) (Protein FAM179B) Mus musculus (Mouse) axoneme assembly [GO:0035082]; cilium assembly [GO:0060271]; microtubule cytoskeleton organization [GO:0000226]; mitotic spindle assembly [GO:0090307]; non-motile cilium assembly [GO:1905515]; positive regulation of microtubule polymerization [GO:0031116] GO:0000226; GO:0005815; GO:0005876; GO:0005881; GO:0005929; GO:0005930; GO:0008017; GO:0031116; GO:0035082; GO:0036064; GO:0060271; GO:0072686; GO:0090307; GO:1905515 33519 XM_029358231.2 1689 1189 1107 1617 1374 Q6A070 1.24e-86 TOG array regulator of axonemal microtubules protein 1 (Crescerin-1) (Protein FAM179B) Mus musculus (Mouse) axoneme assembly [GO:0035082]; cilium assembly [GO:0060271]; microtubule cytoskeleton organization [GO:0000226]; mitotic spindle assembly [GO:0090307]; non-motile cilium assembly [GO:1905515]; positive regulation of microtubule polymerization [GO:0031116] GO:0000226; GO:0005815; GO:0005876; GO:0005881; GO:0005929; GO:0005930; GO:0008017; GO:0031116; GO:0035082; GO:0036064; GO:0060271; GO:0072686; GO:0090307; GO:1905515 33520 XM_044316111.1 435 1305 422 730 316 NA NA NA NA NA NA 33521 XR_006391346.1 4 15 2 16 0 NA NA NA NA NA NA 33522 XR_006391496.1 34 9 0 21 11 NA NA NA NA NA NA 33523 XM_044324021.1 2 3 5 8 4 NA NA NA NA NA NA 33524 XM_029342085.2 3123 3388 1707 2942 2898 Q5EAE3 6.46e-83 Ubiquitin domain-containing protein 2 Bos taurus (Bovine) NA GO:0005737 33525 XM_029337406.2 292 371 207 258 256 B2RUR8 1.42e-92 OTU domain-containing protein 7B (EC 3.4.19.12) (Cellular zinc finger anti-NF-kappa-B protein) (Zinc finger A20 domain-containing protein 1) (Zinc finger protein Cezanne) Mus musculus (Mouse) adaptive immune response [GO:0002250]; in utero embryonic development [GO:0001701]; mucosal immune response [GO:0002385]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein deubiquitination [GO:0016579]; protein deubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0071947]; protein K11-linked deubiquitination [GO:0035871]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536] GO:0000122; GO:0001701; GO:0002250; GO:0002385; GO:0003677; GO:0004843; GO:0005634; GO:0005737; GO:0008234; GO:0008270; GO:0016579; GO:0032717; GO:0035871; GO:0043124; GO:0070530; GO:0070536; GO:0071108; GO:0071947; GO:1900181; GO:1990380 33526 XM_029337247.2 462 306 286 651 360 NA NA NA NA NA NA 33527 XM_044313308.1 0 0 0 0 28 NA NA NA NA NA NA 33528 XM_029345254.2 47 19 8 3 76 NA NA NA NA NA NA 33529 XM_044310375.1 234 635 523 783 345 NA NA NA NA NA NA 33530 XM_044326166.1 1192 665 635 1194 1243 NA NA NA NA NA NA 33531 XM_044328563.1 34 50 140 36 134 F1MBP6 9.23e-41 Kelch-like protein 3 Bos taurus (Bovine) distal tubule morphogenesis [GO:0072156]; gene expression [GO:0010467]; ion homeostasis [GO:0050801]; potassium ion homeostasis [GO:0055075]; protein K48-linked ubiquitination [GO:0070936]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; renal sodium ion absorption [GO:0070294]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0003779; GO:0005829; GO:0005856; GO:0006468; GO:0006511; GO:0010467; GO:0016567; GO:0031463; GO:0050801; GO:0055075; GO:0070294; GO:0070936; GO:0072156; GO:0097602 33532 XM_044320424.1 193 217 90 135 69 NA NA NA NA NA NA 33533 XM_029324546.2 23 3 26 15 208 Q27403 1.11e-46 Transcription factor glial cells missing (Protein glide) Drosophila melanogaster (Fruit fly) dendrite morphogenesis [GO:0048813]; embryonic crystal cell differentiation [GO:0035165]; establishment of glial blood-brain barrier [GO:0060857]; glial cell development [GO:0021782]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; gliogenesis [GO:0042063]; hemocyte development [GO:0007516]; negative regulation of crystal cell differentiation [GO:0042690]; neuron differentiation [GO:0030182]; plasmatocyte differentiation [GO:0042387]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell differentiation [GO:0045687]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of transcription by RNA polymerase II [GO:0045944]; posterior head segmentation [GO:0035289]; regulation of gene expression [GO:0010468]; regulation of hemocyte differentiation [GO:0045610]; regulation of phagocytosis [GO:0050764]; regulation of transcription by RNA polymerase II [GO:0006357]; retinal ganglion cell axon guidance [GO:0031290] GO:0000977; GO:0000978; GO:0000981; GO:0001228; GO:0003677; GO:0005634; GO:0006357; GO:0007403; GO:0007516; GO:0010001; GO:0010468; GO:0010628; GO:0021782; GO:0030182; GO:0031290; GO:0035165; GO:0035289; GO:0042063; GO:0042387; GO:0042690; GO:0045610; GO:0045687; GO:0045893; GO:0045944; GO:0048813; GO:0050764; GO:0060252; GO:0060857 33534 XM_029337066.2 0 42 0 0 0 NA NA NA NA NA NA 33535 XM_044329181.1 472 516 136 552 191 P94598 0 Glutamate dehydrogenase (GDH) (EC 1.4.1.3) (NAD(P)H-utilizing glutamate dehydrogenase) Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) glutamate biosynthetic process [GO:0006537] GO:0004352; GO:0004354; GO:0005829; GO:0006537 33536 XM_029334857.2 539 541 466 527 572 O75899 3.38e-115 Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51) (HG20) Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway [GO:0007186]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; neuron-glial cell signaling [GO:0150099]; synaptic transmission, GABAergic [GO:0051932] GO:0004888; GO:0004965; GO:0005737; GO:0005886; GO:0007186; GO:0007193; GO:0007194; GO:0007214; GO:0007268; GO:0038039; GO:0043005; GO:0045211; GO:0046982; GO:0051932; GO:0150099; GO:1902710; GO:1902712 33537 XM_029351399.2 43 40 40 12 50 Q16515 9.1e-70 Acid-sensing ion channel 2 (ASIC2) (Amiloride-sensitive brain sodium channel) (Amiloride-sensitive cation channel 1, neuronal) (Amiloride-sensitive cation channel neuronal 1) (Brain sodium channel 1) (BNC1) (BNaC1) (Mammalian degenerin homolog) (MDEG) Homo sapiens (Human) central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; establishment of localization in cell [GO:0051649]; inorganic cation transmembrane transport [GO:0098662]; negative regulation of apoptotic process [GO:0043066]; peripheral nervous system development [GO:0007422]; phototransduction [GO:0007602]; positive regulation of synapse assembly [GO:0051965]; protein localization to synapse [GO:0035418]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback [GO:0003026]; regulation of vasoconstriction [GO:0019229]; response to acidic pH [GO:0010447]; sensory perception of sound [GO:0007605]; sensory perception of sour taste [GO:0050915]; sodium ion transmembrane transport [GO:0035725]; synapse assembly [GO:0007416] GO:0003026; GO:0005886; GO:0007268; GO:0007416; GO:0007417; GO:0007422; GO:0007602; GO:0007605; GO:0010447; GO:0015280; GO:0019229; GO:0022839; GO:0034765; GO:0035418; GO:0035725; GO:0042391; GO:0043025; GO:0043066; GO:0043197; GO:0050915; GO:0050974; GO:0051649; GO:0051965; GO:0098662 33538 XM_029353508.2 59 15 4 44 7 NA NA NA NA NA NA 33539 XM_044313076.1 0 69 72 250 365 F8S101 1.49e-27 Phospholipase B (PLB) (EC 3.1.1.-) Crotalus adamanteus (Eastern diamondback rattlesnake) hemolysis in another organism [GO:0044179]; lipid catabolic process [GO:0016042] GO:0004620; GO:0005576; GO:0016042; GO:0044179; GO:0090729 33540 XM_044314160.1 0 104 0 73 61 Q9I8C7 3.57e-77 Neuronal acetylcholine receptor subunit alpha-10 (Alpha 10 nAChR) (Nicotinic acetylcholine receptor subunit alpha-10) (NACHR alpha-10) Gallus gallus (Chicken) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; response to auditory stimulus [GO:0010996]; signal transduction [GO:0007165] GO:0004888; GO:0005231; GO:0005262; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0010996; GO:0022848; GO:0030594; GO:0034220; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051899; GO:1904315 33541 XM_044319474.1 60 34 145 22 169 P0CI65 3.42e-47 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 33542 XM_044319474.1 60 34 145 22 169 P0CI65 2.94e-45 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 33543 XM_029346306.2 30 17 29 93 45 Q6L8S8 1.7e-57 Beta-1,4-N-acetylgalactosaminyltransferase 3 (Beta4GalNAc-T3) (Beta4GalNAcT3) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase III) (N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 2) (NGalNAc-T2) Mus musculus (Mouse) chondroitin sulfate biosynthetic process [GO:0030206] GO:0005794; GO:0008376; GO:0030206; GO:0032580; GO:0033842; GO:0043231; GO:0047238 33544 XM_029342409.2 514 337 231 648 485 Q3KQ80 1.36e-40 O(6)-methylguanine-induced apoptosis 2 (MAPO2) (Sperm-tail PG-rich repeat-containing protein 1) Xenopus laevis (African clawed frog) apoptotic process [GO:0006915]; positive regulation of DNA demethylation [GO:1901537] GO:0005634; GO:0005737; GO:0006915; GO:1901537 33545 XM_044309077.1 16 0 6 0 8 Q09575 9.78e-37 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 33546 XM_029323760.2 2 0 19 23 28 NA NA NA NA NA NA 33547 XM_044329335.1 0 60 0 0 0 Q1PSW8 6.58e-24 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (mLin41) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Mus musculus (Mouse) 3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to organic substance [GO:0071310]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA processing [GO:0035196]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; post-transcriptional regulation of gene expression [GO:0010608]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein metabolic process [GO:0051246]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0001843; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0010608; GO:0017148; GO:0021915; GO:0030371; GO:0035196; GO:0035198; GO:0035278; GO:0043161; GO:0051246; GO:0051865; GO:0060964; GO:0061158; GO:0061630; GO:0071310; GO:0072089; GO:2000177; GO:2000637 33548 XR_003825289.2 11 63 28 34 37 NA NA NA NA NA NA 33549 XM_044321559.1 81 118 159 210 172 NA NA NA NA NA NA 33550 XM_044313493.1 0 0 18 0 0 P07911 1.17e-50 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Homo sapiens (Human) antibacterial innate immune response [GO:0140367]; apoptotic signaling pathway [GO:0097190]; autophagy [GO:0006914]; cellular calcium ion homeostasis [GO:0006874]; cellular chloride ion homeostasis [GO:0030644]; cellular defense response [GO:0006968]; cellular phosphate ion homeostasis [GO:0030643]; cellular response to unfolded protein [GO:0034620]; cellular sodium ion homeostasis [GO:0006883]; chaperone-mediated protein folding [GO:0061077]; citric acid secretion [GO:0046720]; collecting duct development [GO:0072044]; connective tissue replacement [GO:0097709]; creatinine homeostasis [GO:0097273]; defense response to Gram-negative bacterium [GO:0050829]; endoplasmic reticulum organization [GO:0007029]; glomerular filtration [GO:0003094]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; juxtaglomerular apparatus development [GO:0072051]; leukocyte cell-cell adhesion [GO:0007159]; lipid metabolic process [GO:0006629]; metanephric ascending thin limb development [GO:0072218]; metanephric distal convoluted tubule development [GO:0072221]; metanephric thick ascending limb development [GO:0072233]; micturition [GO:0060073]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell population proliferation [GO:0008285]; neutrophil migration [GO:1990266]; organ or tissue specific immune response [GO:0002251]; peptidyl-threonine phosphorylation [GO:0018107]; potassium ion homeostasis [GO:0055075]; protein localization to vacuole [GO:0072665]; protein transport into plasma membrane raft [GO:0044861]; regulation of blood pressure [GO:0008217]; regulation of protein transport [GO:0051223]; regulation of urine volume [GO:0035809]; renal sodium ion absorption [GO:0070294]; renal urate salt excretion [GO:0097744]; renal water homeostasis [GO:0003091]; response to lipopolysaccharide [GO:0032496]; response to water deprivation [GO:0009414]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; ubiquitin-dependent ERAD pathway [GO:0030433]; urate transport [GO:0015747]; urea transmembrane transport [GO:0071918] GO:0000922; GO:0002251; GO:0003091; GO:0003094; GO:0005201; GO:0005509; GO:0005615; GO:0005783; GO:0005796; GO:0005929; GO:0006629; GO:0006874; GO:0006883; GO:0006914; GO:0006954; GO:0006968; GO:0007029; GO:0007157; GO:0007159; GO:0008217; GO:0008285; GO:0008380; GO:0009410; GO:0009414; GO:0009986; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0018107; GO:0019864; GO:0019898; GO:0030433; GO:0030643; GO:0030644; GO:0032496; GO:0033209; GO:0033555; GO:0034620; GO:0035809; GO:0044861; GO:0046720; GO:0050829; GO:0051223; GO:0055075; GO:0060073; GO:0060170; GO:0061077; GO:0070062; GO:0070294; GO:0071918; GO:0072044; GO:0072051; GO:0072218; GO:0072221; GO:0072233; GO:0072665; GO:0097190; GO:0097273; GO:0097709; GO:0097744; GO:0140367; GO:1990266 33551 XM_044319073.1 1311 1016 740 872 767 Q9NX01 8.26e-77 Thioredoxin-like protein 4B (Dim1-like protein) Homo sapiens (Human) cell cycle [GO:0007049]; mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0005654; GO:0005681; GO:0005682; GO:0005829; GO:0007049; GO:0046540 33552 XM_029333695.2 213 154 126 242 183 NA NA NA NA NA NA 33553 XM_044322161.1 0 43 43 0 0 O22943 7.27e-90 Probable glycosyltransferase STELLO1 (EC 2.4.-.-) Arabidopsis thaliana (Mouse-ear cress) plant-type cell wall cellulose biosynthetic process [GO:0052324]; regulation of plant-type cell wall cellulose biosynthetic process [GO:2001009] GO:0000139; GO:0005768; GO:0005794; GO:0005802; GO:0016757; GO:0042802; GO:0052324; GO:2001009 33554 XM_044315173.1 197 33 47 221 141 D4DCG0 8.18e-55 Probable dipeptidyl-aminopeptidase B (DPAP B) (EC 3.4.14.5) Trichophyton verrucosum (strain HKI 0517) proteolysis [GO:0006508] GO:0004177; GO:0004252; GO:0005774; GO:0006508; GO:0008239 33555 XR_003826505.2 223 190 0 176 76 Q86WA9 3.75e-53 Sodium-independent sulfate anion transporter (Solute carrier family 26 member 11) Homo sapiens (Human) ion transport [GO:0006811]; sulfate transport [GO:0008272] GO:0005654; GO:0005765; GO:0005783; GO:0005794; GO:0005886; GO:0006811; GO:0008271; GO:0008272; GO:0008509; GO:0015116; GO:0016020; GO:0043231; GO:0070062 33556 XR_003826505.2 223 190 0 176 76 Q86WA9 3.75e-53 Sodium-independent sulfate anion transporter (Solute carrier family 26 member 11) Homo sapiens (Human) ion transport [GO:0006811]; sulfate transport [GO:0008272] GO:0005654; GO:0005765; GO:0005783; GO:0005794; GO:0005886; GO:0006811; GO:0008271; GO:0008272; GO:0008509; GO:0015116; GO:0016020; GO:0043231; GO:0070062 33557 XM_044321534.1 33 0 14 4 17 P69478 9.41e-41 Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4S-1) (C4ST-1) (C4ST1) Rattus norvegicus (Rat) apoptotic process [GO:0006915]; carbohydrate biosynthetic process [GO:0016051]; cartilage development [GO:0051216]; chondrocyte development [GO:0002063]; chondroitin sulfate biosynthetic process [GO:0030206]; chondroitin sulfate metabolic process [GO:0030204]; developmental growth [GO:0048589]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; embryonic viscerocranium morphogenesis [GO:0048703]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; polysaccharide localization [GO:0033037]; post-anal tail morphogenesis [GO:0036342]; post-embryonic development [GO:0009791]; proteoglycan biosynthetic process [GO:0030166]; regulation of cell population proliferation [GO:0042127]; respiratory gaseous exchange by respiratory system [GO:0007585]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0000139; GO:0001537; GO:0001701; GO:0002063; GO:0006915; GO:0007179; GO:0007585; GO:0008146; GO:0009791; GO:0016051; GO:0030166; GO:0030204; GO:0030206; GO:0030326; GO:0030512; GO:0033037; GO:0036342; GO:0042127; GO:0042733; GO:0043066; GO:0047756; GO:0048589; GO:0048703; GO:0048704; GO:0050659; GO:0051216 33558 XM_044306779.1 40 52 43 23 12 NA NA NA NA NA NA 33559 XM_029334335.2 485 1518 374 587 618 NA NA NA NA NA NA 33560 XM_029338050.2 388 351 98 236 272 NA NA NA NA NA NA 33561 XM_029355978.2 0 86 48 54 0 NA NA NA NA NA NA 33562 XR_006394316.1 25 8 30 14 79 NA NA NA NA NA NA 33563 XM_044315377.1 78 40 70 84 65 NA NA NA NA NA NA 33564 XM_029339450.2 104 4 71 55 80 P55023 2.7e-21 Tyrosinase (EC 1.14.18.1) (Monophenol monooxygenase) Streptomyces lincolnensis melanin biosynthetic process [GO:0042438] GO:0004503; GO:0042438; GO:0046872 33565 XM_044316018.1 0 1 38 0 0 Q13443 1.32e-70 Disintegrin and metalloproteinase domain-containing protein 9 (ADAM 9) (EC 3.4.24.-) (Cellular disintegrin-related protein) (Meltrin-gamma) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) Homo sapiens (Human) amyloid precursor protein catabolic process [GO:0042987]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell migration [GO:0016477]; cell-cell adhesion mediated by integrin [GO:0033631]; cell-matrix adhesion [GO:0007160]; cellular response to lipopolysaccharide [GO:0071222]; integrin-mediated signaling pathway [GO:0007229]; keratinocyte differentiation [GO:0030216]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; monocyte activation [GO:0042117]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of macrophage fusion [GO:0034241]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of protein secretion [GO:0050714]; protein processing [GO:0016485]; response to calcium ion [GO:0051592]; response to glucocorticoid [GO:0051384]; response to hydrogen peroxide [GO:0042542]; response to manganese ion [GO:0010042]; response to tumor necrosis factor [GO:0034612]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0004222; GO:0005080; GO:0005178; GO:0005518; GO:0005615; GO:0005925; GO:0006509; GO:0007155; GO:0007160; GO:0007179; GO:0007229; GO:0008237; GO:0009897; GO:0009986; GO:0010042; GO:0016477; GO:0016485; GO:0017124; GO:0030216; GO:0030335; GO:0031293; GO:0033627; GO:0033630; GO:0033631; GO:0034241; GO:0034612; GO:0042117; GO:0042542; GO:0042987; GO:0043236; GO:0043406; GO:0046872; GO:0050714; GO:0051044; GO:0051384; GO:0051549; GO:0051592; GO:0070062; GO:0071222; GO:1902945 33566 XM_044324385.1 61 43 28 226 161 NA NA NA NA NA NA 33567 XR_003826185.2 220 81 110 176 327 NA NA NA NA NA NA 33568 XM_029338875.2 346 273 190 348 161 NA NA NA NA NA NA 33569 XR_006396136.1 156 191 68 214 373 NA NA NA NA NA NA 33570 XM_029336801.2 114 74 100 114 65 Q9TSL6 5.28e-60 UDP-glucuronosyltransferase 2B23 (UDPGT 2B23) (EC 2.4.1.17) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0005789; GO:0015020 33571 XM_044326639.1 296 269 167 297 286 Q6DUZ9 2.78e-164 EARP-interacting protein homolog Gekko japonicus (Schlegel's Japanese gecko) NA NA 33572 XM_044313252.1 1794 2030 854 1835 2718 Q04637 1.18e-177 Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G 1) (eIF-4G1) (p220) Homo sapiens (Human) behavioral fear response [GO:0001662]; cap-dependent translational initiation [GO:0002191]; cellular macromolecule biosynthetic process [GO:0034645]; cellular response to nutrient levels [GO:0031669]; energy homeostasis [GO:0097009]; lung development [GO:0030324]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of autophagy [GO:0010507]; negative regulation of neuron death [GO:1901215]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; neuron differentiation [GO:0030182]; positive regulation of cell death [GO:0010942]; positive regulation of cell growth [GO:0030307]; positive regulation of eukaryotic translation initiation factor 4F complex assembly [GO:1905537]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of mRNA cap binding [GO:1905612]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of translation in response to endoplasmic reticulum stress [GO:0036493]; regulation of cellular response to stress [GO:0080135]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of polysome binding [GO:1905696]; regulation of presynapse assembly [GO:1905606]; regulation of translational initiation [GO:0006446]; response to ethanol [GO:0045471]; translation [GO:0006412]; translational initiation [GO:0006413] GO:0001662; GO:0002191; GO:0003723; GO:0003729; GO:0003743; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0005844; GO:0006412; GO:0006413; GO:0006446; GO:0008135; GO:0008190; GO:0010494; GO:0010507; GO:0010801; GO:0010942; GO:0016020; GO:0016281; GO:0030182; GO:0030307; GO:0030324; GO:0031369; GO:0031669; GO:0033138; GO:0034645; GO:0035278; GO:0036493; GO:0042802; GO:0045471; GO:0045666; GO:0051247; GO:0060090; GO:0060964; GO:0080135; GO:0097009; GO:0098794; GO:1900087; GO:1901215; GO:1905537; GO:1905606; GO:1905612; GO:1905696 33573 XR_006391741.1 191 230 98 168 244 D3ZAT9 3.63e-46 Failed axon connections homolog Rattus norvegicus (Rat) NA GO:0005737; GO:0016020 33574 XR_006396311.1 193 94 76 77 309 NA NA NA NA NA NA 33575 XR_003826721.2 48 20 77 16 89 NA NA NA NA NA NA 33576 XM_044310369.1 15 4 0 0 0 NA NA NA NA NA NA 33577 XM_044317947.1 94 67 85 103 93 NA NA NA NA NA NA 33578 XM_029334864.2 232 209 24 236 122 NA NA NA NA NA NA 33579 XR_006397231.1 209 0 0 10 0 NA NA NA NA NA NA 33580 XM_029336938.2 1100 924 720 1239 1435 Q8BGA9 4.65e-75 Mitochondrial inner membrane protein OXA1L (Oxidase assembly 1-like protein) (OXA1-like protein) Mus musculus (Mouse) aerobic respiration [GO:0009060]; mitochondrial proton-transporting ATP synthase complex assembly [GO:0033615]; mitochondrial respiratory chain complex I assembly [GO:0032981]; negative regulation of ATP-dependent activity [GO:0032780]; negative regulation of oxidoreductase activity [GO:0051354]; protein insertion into membrane [GO:0051205]; protein insertion into mitochondrial inner membrane from matrix [GO:0032979]; protein tetramerization [GO:0051262] GO:0005739; GO:0005743; GO:0009060; GO:0031966; GO:0032780; GO:0032977; GO:0032979; GO:0032981; GO:0032991; GO:0033615; GO:0042803; GO:0051205; GO:0051262; GO:0051354; GO:0097177 33581 XM_044318074.1 92 44 58 52 58 E3TDS3 1.46e-76 Mitochondrial ribosome-associated GTPase 1 (Mitochondrial GTPase 1) Ictalurus punctatus (Channel catfish) (Silurus punctatus) regulation of translation [GO:0006417] GO:0005525; GO:0005743; GO:0005759; GO:0005761; GO:0006417 33582 XM_044328987.1 133 98 124 133 7 P30974 5.34e-27 Tachykinin-like peptides receptor 86C (NKD) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; inter-male aggressive behavior [GO:0002121]; neuropeptide signaling pathway [GO:0007218]; tachykinin receptor signaling pathway [GO:0007217] GO:0002121; GO:0004995; GO:0005886; GO:0007186; GO:0007217; GO:0007218; GO:0008188; GO:0016020 33583 XM_029354679.2 5 2 19 25 32 NA NA NA NA NA NA 33584 XM_029351987.2 0 79 0 0 49 Q6DDH6 1.54e-40 Histone deacetylase complex subunit SAP130-A (130 kDa Sin3-associated polypeptide A) (Sin3-associated polypeptide p130 A) Xenopus laevis (African clawed frog) regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006355 33585 XM_029355368.2 1 0 10 1 68 NA NA NA NA NA NA 33586 XM_029326259.2 80 98 75 38 152 NA NA NA NA NA NA 33587 XM_044323214.1 0 6 17 8 0 P0CT39 6.68e-66 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 33588 XM_029325340.2 51 17 8 26 9 O35750 1.9e-22 Short stature homeobox protein 2 (Paired family homeodomain protein Prx3) Rattus norvegicus (Rat) cardiac atrium morphogenesis [GO:0003209]; cardiac pacemaker cell differentiation [GO:0060920]; cardiac right atrium morphogenesis [GO:0003213]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; chondrocyte development [GO:0002063]; chondrocyte differentiation [GO:0002062]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic forelimb morphogenesis [GO:0035115]; embryonic limb morphogenesis [GO:0030326]; embryonic morphogenesis [GO:0048598]; embryonic skeletal joint morphogenesis [GO:0060272]; heart valve development [GO:0003170]; mesenchymal cell proliferation [GO:0010463]; muscle tissue morphogenesis [GO:0060415]; negative regulation of transcription by RNA polymerase II [GO:0000122]; osteoblast differentiation [GO:0001649]; positive regulation of axonogenesis [GO:0050772]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of skeletal muscle fiber development [GO:0048743]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of branching morphogenesis of a nerve [GO:2000172]; regulation of chondrocyte differentiation [GO:0032330]; regulation of heart rate [GO:0002027]; regulation of transcription by RNA polymerase II [GO:0006357]; sinoatrial node cell development [GO:0060931]; sinoatrial node development [GO:0003163]; sinoatrial valve development [GO:0003172]; smoothened signaling pathway [GO:0007224]; stem cell proliferation [GO:0072089] GO:0000122; GO:0000981; GO:0001649; GO:0002027; GO:0002053; GO:0002062; GO:0002063; GO:0003163; GO:0003170; GO:0003172; GO:0003209; GO:0003213; GO:0005634; GO:0006357; GO:0007224; GO:0010463; GO:0030326; GO:0032330; GO:0035115; GO:0043565; GO:0045880; GO:0045944; GO:0048557; GO:0048598; GO:0048743; GO:0050772; GO:0060272; GO:0060351; GO:0060415; GO:0060920; GO:0060931; GO:0072089; GO:1990837; GO:2000172; GO:2000648 33589 XM_044320493.1 76 75 32 152 134 NA NA NA NA NA NA 33590 XM_029354730.2 0 0 135 0 0 Q3S8M4 6.73e-95 Elongation of very long chain fatty acids protein 4 (EC 2.3.1.199) (3-keto acyl-CoA synthase ELOVL4) (ELOVL fatty acid elongase 4) (ELOVL FA elongase 4) (Very long chain 3-ketoacyl-CoA synthase 4) (Very long chain 3-oxoacyl-CoA synthase 4) Macaca mulatta (Rhesus macaque) fatty acid elongation, monounsaturated fatty acid [GO:0034625]; fatty acid elongation, polyunsaturated fatty acid [GO:0034626]; fatty acid elongation, saturated fatty acid [GO:0019367]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; sphingolipid biosynthetic process [GO:0030148]; unsaturated fatty acid biosynthetic process [GO:0006636]; very long-chain fatty acid biosynthetic process [GO:0042761] GO:0005783; GO:0005789; GO:0006636; GO:0009922; GO:0019367; GO:0030148; GO:0034625; GO:0034626; GO:0035338; GO:0042761; GO:0102756 33591 XM_029338988.2 3403 6595 4643 18901 5170 Q99042 3.44e-37 D-amino-acid oxidase (DAAO) (DAMOX) (DAO) (EC 1.4.3.3) Trigonopsis variabilis (Yeast) D-amino acid metabolic process [GO:0046416] GO:0003884; GO:0046416; GO:0071949 33592 XM_044319636.1 5 0 0 0 10 P30974 8.46e-33 Tachykinin-like peptides receptor 86C (NKD) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; inter-male aggressive behavior [GO:0002121]; neuropeptide signaling pathway [GO:0007218]; tachykinin receptor signaling pathway [GO:0007217] GO:0002121; GO:0004995; GO:0005886; GO:0007186; GO:0007217; GO:0007218; GO:0008188; GO:0016020 33593 XM_044315513.1 9 0 2 0 21 NA NA NA NA NA NA 33594 XM_029352617.2 122 200 166 357 379 Q5NDL0 0 EGF domain-specific O-linked N-acetylglucosamine transferase (EC 2.4.1.255) (Extracellular O-linked N-acetylglucosamine transferase) Rattus norvegicus (Rat) protein O-GlcNAcylation via threonine [GO:0097370]; protein O-linked glycosylation [GO:0006493] GO:0005788; GO:0006493; GO:0008375; GO:0016262; GO:0016757; GO:0097363; GO:0097370 33595 XM_029342604.2 674 396 355 847 1165 Q9VBW3 2.58e-85 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 33596 XM_044323020.1 1565 0 0 0 0 P02466 4.69e-46 Collagen alpha-2(I) chain (Alpha-2 type I collagen) Rattus norvegicus (Rat) blood vessel development [GO:0001568]; bone mineralization [GO:0030282]; cellular response to amino acid stimulus [GO:0071230]; cellular response to organic substance [GO:0071310]; cellular response to retinoic acid [GO:0071300]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; extracellular matrix assembly [GO:0085029]; extracellular matrix organization [GO:0030198]; protein heterotrimerization [GO:0070208]; regulation of blood pressure [GO:0008217]; response to norepinephrine [GO:0071873]; Rho protein signal transduction [GO:0007266]; skeletal system development [GO:0001501]; skin morphogenesis [GO:0043589]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001501; GO:0001568; GO:0002020; GO:0005201; GO:0005576; GO:0005581; GO:0005584; GO:0005615; GO:0007179; GO:0007266; GO:0008217; GO:0030198; GO:0030199; GO:0030282; GO:0030674; GO:0031012; GO:0032963; GO:0042802; GO:0043589; GO:0046332; GO:0046872; GO:0048407; GO:0062023; GO:0070208; GO:0071230; GO:0071300; GO:0071310; GO:0071873; GO:0085029; GO:0097067 33597 XM_029351167.2 27 0 0 13 2 NA NA NA NA NA NA 33598 XM_029358134.2 26 17 20 22 5 Q5U2R1 1.49e-69 All trans-polyprenyl-diphosphate synthase PDSS2 (All-trans-decaprenyl-diphosphate synthase subunit 2) (EC 2.5.1.91) (Decaprenyl-diphosphate synthase subunit 2) (Solanesyl-diphosphate synthase subunit 2) Rattus norvegicus (Rat) cerebellum development [GO:0021549]; isoprenoid biosynthetic process [GO:0008299]; regulation of body fluid levels [GO:0050878]; ubiquinone biosynthetic process [GO:0006744] GO:0000010; GO:0004659; GO:0005739; GO:0005829; GO:0006744; GO:0008299; GO:0021549; GO:0046982; GO:0050878; GO:0052923; GO:0097269; GO:1990234 33599 XM_029352256.2 2504 2605 1612 2859 2241 Q8N6S4 0 Ankyrin repeat domain-containing protein 13C Homo sapiens (Human) protein retention in ER lumen [GO:0006621]; regulation of anoikis [GO:2000209]; regulation of signaling receptor activity [GO:0010469] GO:0005102; GO:0005737; GO:0005783; GO:0005789; GO:0006621; GO:0010469; GO:0048471; GO:2000209 33600 XM_044315968.1 4 25 0 103 0 NA NA NA NA NA NA 33601 XM_029330566.2 185 69 104 54 47 Q9Y5X5 7.18e-31 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (G-protein coupled receptor HLWAR77) (Neuropeptide G-protein coupled receptor) Homo sapiens (Human) detection of abiotic stimulus [GO:0009582]; G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0009582; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 33602 XM_044324012.1 0 103 5 37 50 NA NA NA NA NA NA 33603 XM_029332232.2 113 47 38 71 108 NA NA NA NA NA NA 33604 XM_029356969.2 16 0 25 0 563 Q15JG7 1.34e-25 Validamycin A dioxygenase (EC 1.14.11.52) (Alpha-ketoglutarate/Fe(II)-dependent dioxygenase VldW) (Validamycin B synthase) Streptomyces hygroscopicus subsp. limoneus antibiotic biosynthetic process [GO:0017000] GO:0005506; GO:0017000; GO:0051213 33605 XM_029341218.2 6158 8420 5691 6134 10255 Q640R7 2.03e-100 Ras-related protein Rap-1b (EC 3.6.5.2) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) Rap protein signal transduction [GO:0032486] GO:0003925; GO:0005525; GO:0005829; GO:0005886; GO:0032486; GO:0070161 33606 XM_044309085.1 34 28 26 17 17 NA NA NA NA NA NA 33607 XM_044307808.1 2 0 12 8 0 P0DP43 1.82e-32 Cation channel sperm-associated auxiliary subunit epsilon (CatSper-epsilon) (CatSperepsilon) (C1orf101-like protein) Mus musculus (Mouse) flagellated sperm motility [GO:0030317]; sperm capacitation [GO:0048240] GO:0030317; GO:0036128; GO:0048240; GO:0097228 33608 XM_044324732.1 0 8 0 14 4 NA NA NA NA NA NA 33609 XM_044314223.1 2 0 0 8 0 NA NA NA NA NA NA 33610 XM_044308232.1 176 123 85 156 149 Q9CQ24 2.79e-22 F-box only protein 36 Mus musculus (Mouse) NA NA 33611 XM_029333545.2 781 358 604 774 943 D4A8G9 2.33e-134 Zinc finger FYVE domain-containing protein 26 Rattus norvegicus (Rat) autophagosome organization [GO:1905037]; double-strand break repair via homologous recombination [GO:0000724]; lysosome organization [GO:0007040]; mitotic cytokinesis [GO:0000281]; regulation of cytokinesis [GO:0032465] GO:0000281; GO:0000724; GO:0005764; GO:0005769; GO:0005770; GO:0005813; GO:0007040; GO:0019901; GO:0030496; GO:0032266; GO:0032465; GO:0046872; GO:1905037 33612 XM_029333545.2 781 358 604 774 943 D4A8G9 7e-26 Zinc finger FYVE domain-containing protein 26 Rattus norvegicus (Rat) autophagosome organization [GO:1905037]; double-strand break repair via homologous recombination [GO:0000724]; lysosome organization [GO:0007040]; mitotic cytokinesis [GO:0000281]; regulation of cytokinesis [GO:0032465] GO:0000281; GO:0000724; GO:0005764; GO:0005769; GO:0005770; GO:0005813; GO:0007040; GO:0019901; GO:0030496; GO:0032266; GO:0032465; GO:0046872; GO:1905037 33613 XM_029333545.2 781 358 604 774 943 D4A8G9 3.05e-23 Zinc finger FYVE domain-containing protein 26 Rattus norvegicus (Rat) autophagosome organization [GO:1905037]; double-strand break repair via homologous recombination [GO:0000724]; lysosome organization [GO:0007040]; mitotic cytokinesis [GO:0000281]; regulation of cytokinesis [GO:0032465] GO:0000281; GO:0000724; GO:0005764; GO:0005769; GO:0005770; GO:0005813; GO:0007040; GO:0019901; GO:0030496; GO:0032266; GO:0032465; GO:0046872; GO:1905037 33614 XM_044324408.1 85 17 90 94 664 NA NA NA NA NA NA 33615 XM_044321497.1 494 0 0 0 0 Q01804 3.27e-71 OTU domain-containing protein 4 (EC 3.4.19.12) (HIV-1-induced protein HIN-1) Homo sapiens (Human) innate immune response [GO:0045087]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; positive regulation of DNA demethylation [GO:1901537]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; regulation of protein K48-linked deubiquitination [GO:1903093] GO:0003723; GO:0004843; GO:0005634; GO:0005829; GO:0016579; GO:0034122; GO:0045087; GO:0060090; GO:0061578; GO:0070536; GO:0071108; GO:1901537; GO:1903093; GO:2000660 33616 XM_044319374.1 0 0 0 0 6 NA NA NA NA NA NA 33617 XM_029348787.2 246 163 45 276 223 Q9BZ29 0 Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin-1) (Zizimin-1) Homo sapiens (Human) positive regulation of GTPase activity [GO:0043547]; small GTPase mediated signal transduction [GO:0007264] GO:0005085; GO:0005829; GO:0007264; GO:0012505; GO:0016020; GO:0043547; GO:0045296 33618 XR_006393553.1 0 1 8 0 0 NA NA NA NA NA NA 33619 XM_029343851.2 33 1 36 0 111 Q75N90 1.38e-67 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 33620 XM_029343851.2 33 1 36 0 111 Q75N90 8.05e-51 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 33621 XM_029343851.2 33 1 36 0 111 Q75N90 1.46e-45 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 33622 XM_029343851.2 33 1 36 0 111 Q75N90 9.74e-44 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 33623 XM_029343851.2 33 1 36 0 111 Q75N90 1.95e-42 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 33624 XM_029343851.2 33 1 36 0 111 Q75N90 3.87e-41 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 33625 XM_029343851.2 33 1 36 0 111 Q75N90 1.75e-40 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 33626 XM_029343851.2 33 1 36 0 111 Q75N90 5.8e-33 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 33627 XM_029343851.2 33 1 36 0 111 Q75N90 1.01e-32 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 33628 XM_029343851.2 33 1 36 0 111 Q75N90 1.14e-30 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 33629 XM_029343851.2 33 1 36 0 111 Q75N90 3.11e-30 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 33630 XM_029343851.2 33 1 36 0 111 Q75N90 5.17e-28 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 33631 XM_029343851.2 33 1 36 0 111 Q75N90 6.71e-26 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 33632 XM_044327268.1 9 3 1 2 0 NA NA NA NA NA NA 33633 XM_029351575.2 408 340 269 458 535 Q9Y6V7 1.18e-171 Probable ATP-dependent RNA helicase DDX49 (EC 3.6.4.13) (DEAD box protein 49) Homo sapiens (Human) positive regulation of cell growth [GO:0030307]; regulation of rRNA stability [GO:0044357]; rRNA processing [GO:0006364] GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005654; GO:0006364; GO:0016887; GO:0030307; GO:0044357 33634 XM_044323970.1 38 7 25 7 3 NA NA NA NA NA NA 33635 XM_029331406.2 15 0 0 73 9 Q5BKF8 5.12e-111 Cyclin-L2 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) regulation of transcription by RNA polymerase II [GO:0006357] GO:0006357; GO:0016538; GO:0016607 33636 XR_006397425.1 44 0 0 0 104 NA NA NA NA NA NA 33637 XM_044312267.1 0 0 0 160 1 NA NA NA NA NA NA 33638 XR_006391281.1 405 0 74 74 966 NA NA NA NA NA NA 33639 XM_044326023.1 0 78 0 0 0 Q9UKV8 4.93e-153 Protein argonaute-2 (Argonaute2) (hAgo2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (PAZ Piwi domain protein) (PPD) (Protein slicer) Homo sapiens (Human) miRNA metabolic process [GO:0010586]; miRNA processing [GO:0035196]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; miRNA-mediated gene silencing by mRNA destabilization [GO:0035279]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; negative regulation of translational initiation [GO:0045947]; positive regulation of angiogenesis [GO:0045766]; positive regulation of gene expression [GO:0010628]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of trophoblast cell migration [GO:1901165]; post-embryonic development [GO:0009791]; pre-miRNA processing [GO:0031054]; RISC complex assembly [GO:0070922]; RNA secondary structure unwinding [GO:0010501]; RNA-mediated gene silencing [GO:0031047]; RNA-mediated post-transcriptional gene silencing [GO:0035194]; siRNA processing [GO:0030422]; siRNA-mediated gene silencing by mRNA destabilization [GO:0090625]; translation [GO:0006412] GO:0000340; GO:0000932; GO:0000993; GO:0001046; GO:0003723; GO:0003725; GO:0003727; GO:0003743; GO:0004521; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005844; GO:0005845; GO:0006412; GO:0008022; GO:0009791; GO:0010501; GO:0010586; GO:0010628; GO:0016020; GO:0016442; GO:0030422; GO:0030425; GO:0031047; GO:0031054; GO:0035194; GO:0035196; GO:0035197; GO:0035198; GO:0035278; GO:0035279; GO:0036464; GO:0042985; GO:0045766; GO:0045944; GO:0045947; GO:0046872; GO:0060213; GO:0070062; GO:0070551; GO:0070578; GO:0070922; GO:0090624; GO:0090625; GO:0098808; GO:1900153; GO:1901165; GO:1990904 33640 XM_044323211.1 0 0 4 7 7 NA NA NA NA NA NA 33641 XR_006393540.1 15 9 0 0 4 NA NA NA NA NA NA 33642 XM_029328998.2 57 7 94 0 11 Q8N543 9.29e-143 Prolyl 3-hydroxylase OGFOD1 (EC 1.14.11.-) (2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1) (Termination and polyadenylation 1 homolog) (uS12 prolyl 3-hydroxylase) Homo sapiens (Human) cell population proliferation [GO:0008283]; peptidyl-proline hydroxylation [GO:0019511]; protein hydroxylation [GO:0018126]; regulation of translational termination [GO:0006449]; stress granule assembly [GO:0034063] GO:0005506; GO:0005654; GO:0005737; GO:0005829; GO:0006449; GO:0008283; GO:0010494; GO:0018126; GO:0019511; GO:0031418; GO:0031543; GO:0031544; GO:0034063 33643 XM_044322943.1 702 566 427 358 366 NA NA NA NA NA NA 33644 XM_029329882.2 40 42 95 0 73 O31463 5.08e-53 Homocysteine S-methyltransferase YbgG (EC 2.1.1.10) (S-methylmethionine:homocysteine methyltransferase) Bacillus subtilis (strain 168) methionine biosynthetic process [GO:0009086]; methylation [GO:0032259]; S-methylmethionine cycle [GO:0033528] GO:0008270; GO:0008898; GO:0009086; GO:0032259; GO:0033528; GO:0061627 33645 XM_044327853.1 0 0 86 118 20 NA NA NA NA NA NA 33646 XM_044328547.1 0 0 12 0 45 Q6NVC5 0 Mitochondrial Rho GTPase 1-A (MIRO-1-A) (EC 3.6.5.-) (Ras homolog gene family member T1-A) Danio rerio (Zebrafish) (Brachydanio rerio) cellular homeostasis [GO:0019725]; mitochondrial outer membrane permeabilization [GO:0097345]; mitochondrion organization [GO:0007005]; mitochondrion transport along microtubule [GO:0047497]; regulation of mitochondrion organization [GO:0010821]; small GTPase mediated signal transduction [GO:0007264] GO:0003924; GO:0005509; GO:0005525; GO:0005739; GO:0005741; GO:0007005; GO:0007264; GO:0010821; GO:0019725; GO:0047497; GO:0097345 33647 XM_044317779.1 735 930 539 1182 646 Q8TBY9 0 Cilia- and flagella-associated protein 251 (WD repeat-containing protein 66) Homo sapiens (Human) cilium movement [GO:0003341]; flagellated sperm motility [GO:0030317] GO:0003341; GO:0005930; GO:0030317; GO:0031514; GO:0036126 33648 XM_029340276.2 28 2 2 16 18 Q5RA50 9.82e-26 Protein FAM124A Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA NA 33649 XM_029338201.2 1267 1176 1320 1417 834 Q5EA33 4.04e-45 Ankyrin repeat domain-containing protein 49 Bos taurus (Bovine) cell differentiation [GO:0030154]; positive regulation of DNA-templated transcription [GO:0045893]; spermatogenesis [GO:0007283] GO:0005634; GO:0005829; GO:0007283; GO:0030154; GO:0045893 33650 XM_044309044.1 462 247 38 177 315 NA NA NA NA NA NA 33651 XR_006398062.1 0 0 14 0 0 NA NA NA NA NA NA 33652 XM_029329973.2 0 1 0 6 0 Q8WMS0 6.34e-68 UDP-galactose translocator (Solute carrier family 35 member A2) (UDP-galactose transporter) (UDP-Gal-Tr) (UGT) Canis lupus familiaris (Dog) (Canis familiaris) carbohydrate transport [GO:0008643] GO:0000139; GO:0005459; GO:0008643 33653 XM_044327471.1 0 0 1 0 22 NA NA NA NA NA NA 33654 XM_029353731.2 39 47 27 33 33 NA NA NA NA NA NA 33655 XM_029332116.2 40 19 22 20 81 NA NA NA NA NA NA 33656 XM_029349413.2 0 30 0 0 0 NA NA NA NA NA NA 33657 XM_044329353.1 16 0 24 9 56 Q9NUV7 4.49e-25 Serine palmitoyltransferase 3 (EC 2.3.1.50) (Long chain base biosynthesis protein 2b) (LCB2b) (Long chain base biosynthesis protein 3) (LCB 3) (Serine-palmitoyl-CoA transferase 3) (SPT 3) Homo sapiens (Human) ceramide biosynthetic process [GO:0046513]; sphingoid biosynthetic process [GO:0046520]; sphingolipid biosynthetic process [GO:0030148]; sphingosine biosynthetic process [GO:0046512] GO:0004758; GO:0005789; GO:0017059; GO:0030148; GO:0030170; GO:0046512; GO:0046513; GO:0046520 33658 XM_029354459.2 1051 1262 654 1486 1042 P90543 1.14e-43 Histone H3 Euplotes crassus NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 33659 XM_029358047.2 2268 1047 1821 1200 1423 O81884 4.08e-85 L-galactose dehydrogenase (At-GalDH) (L-GalDH) (EC 1.1.1.316) Arabidopsis thaliana (Mouse-ear cress) galactose metabolic process [GO:0006012]; L-ascorbic acid biosynthetic process [GO:0019853] GO:0005829; GO:0006012; GO:0010349; GO:0016491; GO:0019853 33660 XM_044324845.1 212 159 118 127 104 P84079 3.17e-81 ADP-ribosylation factor 1 (EC 3.6.5.2) Rattus norvegicus (Rat) actin filament organization [GO:0007015]; cellular copper ion homeostasis [GO:0006878]; cellular response to virus [GO:0098586]; dendritic spine organization [GO:0097061]; Golgi to transport vesicle transport [GO:0055108]; intracellular protein transport [GO:0006886]; long-term synaptic depression [GO:0060292]; lysosomal membrane organization [GO:0097212]; mitotic cleavage furrow ingression [GO:1990386]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of endocytosis [GO:0045807]; positive regulation of ER to Golgi vesicle-mediated transport [GO:1902953]; positive regulation of late endosome to lysosome transport [GO:1902824]; positive regulation of protein secretion [GO:0050714]; positive regulation of sodium ion transmembrane transport [GO:1902307]; postsynaptic actin cytoskeleton organization [GO:0098974]; regulation of Arp2/3 complex-mediated actin nucleation [GO:0034315]; regulation of phospholipid metabolic process [GO:1903725]; regulation of receptor internalization [GO:0002090]; synaptic vesicle budding [GO:0070142]; very-low-density lipoprotein particle assembly [GO:0034379]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0000287; GO:0002090; GO:0003924; GO:0005525; GO:0005737; GO:0005770; GO:0005794; GO:0005829; GO:0005886; GO:0006878; GO:0006886; GO:0007015; GO:0012505; GO:0014069; GO:0016192; GO:0019003; GO:0019904; GO:0030017; GO:0031252; GO:0032991; GO:0034315; GO:0034379; GO:0043005; GO:0045807; GO:0045956; GO:0050714; GO:0055108; GO:0060292; GO:0060999; GO:0070142; GO:0097061; GO:0097212; GO:0098586; GO:0098974; GO:0098978; GO:1902307; GO:1902824; GO:1902953; GO:1903725; GO:1990386; GO:1990583 33661 XM_044311812.1 543 37 251 111 244 Q96AY4 6.43e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33662 XM_029333346.2 0 24 0 0 0 NA NA NA NA NA NA 33663 XR_006393370.1 53 38 2 27 22 NA NA NA NA NA NA 33664 XM_029342687.2 14 32 9 5 18 NA NA NA NA NA NA 33665 XM_029355872.2 22 33 0 0 45 D3YY91 7.32e-78 Leucine-rich repeat protein 1 Mus musculus (Mouse) protein ubiquitination [GO:0016567] GO:0005634; GO:0016567 33666 XR_006391877.1 0 45 0 0 39 P49642 2.36e-155 DNA primase small subunit (EC 2.7.7.102) (DNA primase 49 kDa subunit) (p49) Homo sapiens (Human) DNA replication initiation [GO:0006270]; DNA replication, synthesis of RNA primer [GO:0006269] GO:0000287; GO:0003896; GO:0005654; GO:0005658; GO:0006269; GO:0006270; GO:0008270; GO:0016020; GO:0032553 33667 XM_029339891.2 1607 1158 949 1217 1453 O60216 1.21e-82 Double-strand-break repair protein rad21 homolog (hHR21) (Nuclear matrix protein 1) (NXP-1) (SCC1 homolog) [Cleaved into: 64-kDa C-terminal product (64-kDa carboxy-terminal product) (65-kDa carboxy-terminal product)] Homo sapiens (Human) apoptotic process [GO:0006915]; cell division [GO:0051301]; chromatin looping [GO:0140588]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; establishment of meiotic sister chromatid cohesion [GO:0034089]; establishment of mitotic sister chromatid cohesion [GO:0034087]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; negative regulation of mitotic metaphase/anaphase transition [GO:0045841]; positive regulation of sister chromatid cohesion [GO:0045876]; protein localization to chromatin [GO:0071168]; reciprocal meiotic recombination [GO:0007131]; regulation of transcription by RNA polymerase II [GO:0006357]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414]; sister chromatid cohesion [GO:0007062] GO:0000775; GO:0000785; GO:0000794; GO:0000922; GO:0003677; GO:0003682; GO:0005634; GO:0005654; GO:0005694; GO:0005829; GO:0006302; GO:0006310; GO:0006357; GO:0006915; GO:0007062; GO:0007131; GO:0008278; GO:0010972; GO:0016020; GO:0016363; GO:0030496; GO:0034087; GO:0034089; GO:0045841; GO:0045876; GO:0051301; GO:0071168; GO:0140588; GO:1990414 33668 XM_029328206.2 13 3 4 4 2 NA NA NA NA NA NA 33669 XM_044322425.1 160 103 68 45 55 NA NA NA NA NA NA 33670 XM_044325756.1 44 3 3 10 5 NA NA NA NA NA NA 33671 XM_029327532.2 0 0 8 5 8 NA NA NA NA NA NA 33672 XM_029355382.2 1073 1322 432 735 584 NA NA NA NA NA NA 33673 XM_044315217.1 739 7 183 138 86 NA NA NA NA NA NA 33674 XR_006397034.1 2 3 0 3 25 NA NA NA NA NA NA 33675 XM_044326628.1 0 7 0 0 0 NA NA NA NA NA NA 33676 XM_029326244.2 1718 4512 811 1307 725 NA NA NA NA NA NA 33677 XM_029346319.2 136 206 74 122 125 Q5RBA4 1.93e-40 Myosin regulatory light polypeptide 9 (Myosin regulatory light chain 2, smooth muscle isoform) (Myosin regulatory light chain 9) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0005509; GO:0005938; GO:0016459 33678 XM_044313624.1 47 10 41 21 84 NA NA NA NA NA NA 33679 XM_029357038.2 1184 972 530 1347 1602 Q9Z0K8 6.05e-144 Pantetheinase (EC 3.5.1.92) (Pantetheine hydrolase) (Vascular non-inflammatory molecule 1) (Vanin-1) Mus musculus (Mouse) acute inflammatory response [GO:0002526]; cell-cell adhesion [GO:0098609]; chronic inflammatory response [GO:0002544]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; pantothenate metabolic process [GO:0015939]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of T cell differentiation in thymus [GO:0033089] GO:0002526; GO:0002544; GO:0005886; GO:0006954; GO:0015939; GO:0016020; GO:0017159; GO:0033089; GO:0034235; GO:0045087; GO:0098609; GO:1902177 33680 XM_029346511.2 551 349 303 561 473 Q6ZQ11 0 Chondroitin sulfate synthase 1 (EC 2.4.1.175) (EC 2.4.1.226) (Chondroitin glucuronyltransferase 1) (Chondroitin synthase 1) (ChSy-1) (Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1) (N-acetylgalactosaminyltransferase 1) Mus musculus (Mouse) bone morphogenesis [GO:0060349]; cartilage development [GO:0051216]; chondrocyte development [GO:0002063]; chondroitin sulfate biosynthetic process [GO:0030206]; negative regulation of ossification [GO:0030279]; positive regulation of smoothened signaling pathway [GO:0045880]; proximal/distal pattern formation [GO:0009954]; response to nutrient levels [GO:0031667]; sulfation [GO:0051923] GO:0002063; GO:0005576; GO:0005794; GO:0008376; GO:0009954; GO:0016757; GO:0030206; GO:0030279; GO:0031667; GO:0032580; GO:0045880; GO:0046872; GO:0047238; GO:0050510; GO:0051216; GO:0051923; GO:0060349 33681 XM_029342659.2 67 31 55 0 64 NA NA NA NA NA NA 33682 XM_029339295.2 80 0 0 90 102 NA NA NA NA NA NA 33683 XM_044308029.1 0 0 58 0 0 NA NA NA NA NA NA 33684 XM_044318977.1 125 155 119 59 111 Q3ZCC3 5.91e-111 TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6) Bos taurus (Bovine) activation of NF-kappaB-inducing kinase activity [GO:0007250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; bone resorption [GO:0045453]; cellular response to DNA damage stimulus [GO:0006974]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; in utero embryonic development [GO:0001701]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-17-mediated signaling pathway [GO:0097400]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin production [GO:0002637]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000122; GO:0001503; GO:0001701; GO:0001843; GO:0002637; GO:0002726; GO:0004842; GO:0005164; GO:0005634; GO:0005811; GO:0005829; GO:0005938; GO:0006974; GO:0007249; GO:0007250; GO:0008270; GO:0009898; GO:0019886; GO:0030316; GO:0031435; GO:0031624; GO:0031625; GO:0031663; GO:0031666; GO:0031996; GO:0032735; GO:0032743; GO:0032755; GO:0032813; GO:0033209; GO:0035631; GO:0042088; GO:0042102; GO:0042475; GO:0042802; GO:0042826; GO:0042981; GO:0043011; GO:0043122; GO:0043123; GO:0043422; GO:0043507; GO:0045453; GO:0045672; GO:0045944; GO:0046330; GO:0047485; GO:0048471; GO:0050852; GO:0051092; GO:0051865; GO:0061630; GO:0070498; GO:0070534; GO:0097400; GO:1901224; GO:1904996; GO:2000679 33685 XR_006396664.1 16 9 344 534 30 NA NA NA NA NA NA 33686 XM_044315635.1 23 27 6 9 12 NA NA NA NA NA NA 33687 XM_044322983.1 56 0 2 26 1 NA NA NA NA NA NA 33688 XM_029328622.2 0 0 0 70 0 Q1WK23 1.33e-38 Serine protease 23 (EC 3.4.21.-) Macaca mulatta (Rhesus macaque) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 33689 XR_006395706.1 300 252 195 174 138 NA NA NA NA NA NA 33690 XM_029358212.2 5508 7725 5082 5039 4640 Q5R9W6 4.71e-43 Transcription initiation factor TFIID subunit 13 (Transcription initiation factor TFIID 18 kDa subunit) (TAF(II)18) (TAFII-18) (TAFII18) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) mRNA transcription by RNA polymerase II [GO:0042789]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; protein phosphorylation [GO:0006468]; RNA polymerase II preinitiation complex assembly [GO:0051123] GO:0003677; GO:0005669; GO:0005730; GO:0006468; GO:0008022; GO:0017025; GO:0042789; GO:0046982; GO:0051123; GO:0060261 33691 XM_029327484.2 696 321 443 672 950 Q6L9W6 3.61e-92 Beta-1,4-N-acetylgalactosaminyltransferase 3 (B4GalNAcT3) (Beta4GalNAc-T3) (Beta4GalNAcT3) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase III) (N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 2) (NGalNAc-T2) Homo sapiens (Human) NA GO:0005794; GO:0008376; GO:0032580; GO:0033842; GO:0043231 33692 XM_029327484.2 696 321 443 672 950 Q6L9W6 1.82e-44 Beta-1,4-N-acetylgalactosaminyltransferase 3 (B4GalNAcT3) (Beta4GalNAc-T3) (Beta4GalNAcT3) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase III) (N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 2) (NGalNAc-T2) Homo sapiens (Human) NA GO:0005794; GO:0008376; GO:0032580; GO:0033842; GO:0043231 33693 XM_044317841.1 3 0 0 0 33 NA NA NA NA NA NA 33694 XM_029341303.2 93 26 55 49 64 NA NA NA NA NA NA 33695 XM_044318970.1 298 43 108 67 128 NA NA NA NA NA NA 33696 XM_029346125.2 769 709 478 583 893 NA NA NA NA NA NA 33697 XM_044328657.1 943 582 179 397 297 P61214 1.93e-48 ADP-ribosylation factor-like protein 4A Rattus norvegicus (Rat) brown fat cell differentiation [GO:0050873]; intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192] GO:0003924; GO:0005525; GO:0005634; GO:0005730; GO:0005737; GO:0005886; GO:0006886; GO:0016192; GO:0050873 33698 XM_044324806.1 10344 10573 7396 11509 7110 Q2HJ40 4.8e-136 Beta-secretase 1 (EC 3.4.23.46) (Beta-site amyloid precursor protein cleaving enzyme 1) (Beta-site APP cleaving enzyme 1) (Memapsin-2) (Membrane-associated aspartic protease 2) Bos taurus (Bovine) amyloid-beta formation [GO:0034205]; amyloid-beta metabolic process [GO:0050435]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; proteolysis [GO:0006508]; signaling receptor ligand precursor processing [GO:0140448] GO:0001540; GO:0004175; GO:0004190; GO:0005764; GO:0005768; GO:0005769; GO:0005770; GO:0005771; GO:0005783; GO:0005794; GO:0005802; GO:0005886; GO:0006508; GO:0006509; GO:0009986; GO:0019899; GO:0030424; GO:0030425; GO:0030659; GO:0034205; GO:0043525; GO:0045121; GO:0050435; GO:0055037; GO:0098686; GO:0098793; GO:0099171; GO:0140448 33699 XR_006396737.1 30 0 10 16 84 NA NA NA NA NA NA 33700 XM_029333649.2 0 0 0 8 34 A0JPI9 8.32e-49 Leucine-rich repeat-containing protein 74A (Leucine-rich repeat-containing protein 74) Rattus norvegicus (Rat) NA NA 33701 XR_006396727.1 0 5 3 18 17 NA NA NA NA NA NA 33702 XM_044323094.1 1387 267 225 889 169 NA NA NA NA NA NA 33703 XR_006391565.1 172 81 101 114 126 NA NA NA NA NA NA 33704 XM_044329114.1 2 9 11 0 7 NA NA NA NA NA NA 33705 XM_044327408.1 0 0 0 67 31 Q49GP3 5.29e-151 Phosphatidylinositol 4-kinase beta (PI4K-beta) (PI4Kbeta) (PtdIns 4-kinase beta) (EC 2.7.1.67) Danio rerio (Zebrafish) (Brachydanio rerio) phosphatidylinositol phosphate biosynthetic process [GO:0046854]; phosphatidylinositol-mediated signaling [GO:0048015]; phosphorylation [GO:0016310]; semicircular canal development [GO:0060872] GO:0004430; GO:0005524; GO:0005737; GO:0005741; GO:0016020; GO:0016310; GO:0030867; GO:0046854; GO:0048015; GO:0052742; GO:0060872 33706 XM_044327408.1 0 0 0 67 31 Q49GP3 1.75e-38 Phosphatidylinositol 4-kinase beta (PI4K-beta) (PI4Kbeta) (PtdIns 4-kinase beta) (EC 2.7.1.67) Danio rerio (Zebrafish) (Brachydanio rerio) phosphatidylinositol phosphate biosynthetic process [GO:0046854]; phosphatidylinositol-mediated signaling [GO:0048015]; phosphorylation [GO:0016310]; semicircular canal development [GO:0060872] GO:0004430; GO:0005524; GO:0005737; GO:0005741; GO:0016020; GO:0016310; GO:0030867; GO:0046854; GO:0048015; GO:0052742; GO:0060872 33707 XM_044327408.1 0 0 0 67 31 Q49GP3 4.54e-23 Phosphatidylinositol 4-kinase beta (PI4K-beta) (PI4Kbeta) (PtdIns 4-kinase beta) (EC 2.7.1.67) Danio rerio (Zebrafish) (Brachydanio rerio) phosphatidylinositol phosphate biosynthetic process [GO:0046854]; phosphatidylinositol-mediated signaling [GO:0048015]; phosphorylation [GO:0016310]; semicircular canal development [GO:0060872] GO:0004430; GO:0005524; GO:0005737; GO:0005741; GO:0016020; GO:0016310; GO:0030867; GO:0046854; GO:0048015; GO:0052742; GO:0060872 33708 XM_044329173.1 7 18 10 36 14 NA NA NA NA NA NA 33709 XM_029323603.2 7395 8431 4084 9012 4509 Q80ZQ5 1.76e-32 Juxtaposed with another zinc finger protein 1 Mus musculus (Mouse) lipid metabolic process [GO:0006629]; negative regulation of transcription by RNA polymerase II [GO:0000122] GO:0000122; GO:0001650; GO:0003714; GO:0005634; GO:0005654; GO:0005829; GO:0006629; GO:0017053; GO:0046872 33710 XM_044313952.1 1615 766 455 1199 1013 A2AIV2 0 Protein virilizer homolog Mus musculus (Mouse) mRNA alternative polyadenylation [GO:0110104]; mRNA methylation [GO:0080009]; mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006397; GO:0008380; GO:0016604; GO:0016607; GO:0036396; GO:0080009; GO:0110104 33711 XM_044313952.1 1615 766 455 1199 1013 A2AIV2 9.88e-26 Protein virilizer homolog Mus musculus (Mouse) mRNA alternative polyadenylation [GO:0110104]; mRNA methylation [GO:0080009]; mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006397; GO:0008380; GO:0016604; GO:0016607; GO:0036396; GO:0080009; GO:0110104 33712 XM_044321448.1 2388 1858 853 1907 1113 NA NA NA NA NA NA 33713 XM_044321266.1 0 78 25 591 433 NA NA NA NA NA NA 33714 XR_006391377.1 54 23 52 16 90 NA NA NA NA NA NA 33715 XM_044325136.1 9 0 0 0 0 NA NA NA NA NA NA 33716 XM_044327766.1 52 16 57 51 31 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33717 XM_044327766.1 52 16 57 51 31 Q96AY4 1.48e-142 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33718 XM_044327766.1 52 16 57 51 31 Q96AY4 2.41e-94 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33719 XM_044327766.1 52 16 57 51 31 Q96AY4 4.15e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33720 XM_029339432.2 0 0 0 318 0 Q7T163 2.17e-154 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 33721 XM_029339432.2 0 0 0 318 0 Q7T163 7.42e-42 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 33722 XM_029341497.2 215 153 168 195 310 Q9UGK8 3.5e-68 Secretion-regulating guanine nucleotide exchange factor (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF) (Guanine nucleotide exchange factor-related protein) Homo sapiens (Human) negative regulation of protein secretion [GO:0050709]; signal transduction [GO:0007165] GO:0005085; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0007165; GO:0050709 33723 XM_029342223.2 427 398 231 389 206 Q9BSG0 1.45e-45 Protease-associated domain-containing protein 1 (Protease-associated domain-containing protein of 21 kDa) (hPAP21) Homo sapiens (Human) NA GO:0005576 33724 XM_044322287.1 77 404 204 504 29 NA NA NA NA NA NA 33725 XM_029348395.2 70 0 0 63 47 Q9JJS6 8.38e-105 Beta,beta-carotene 15,15'-dioxygenase (EC 1.13.11.63) (Beta-carotene dioxygenase 1) (Beta-carotene oxygenase 1) Mus musculus (Mouse) beta-carotene metabolic process [GO:1901810]; carotene catabolic process [GO:0016121]; retinal metabolic process [GO:0042574]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572] GO:0001523; GO:0003834; GO:0005829; GO:0010436; GO:0016121; GO:0042572; GO:0042574; GO:0046872; GO:1901810 33726 XM_044314968.1 75 51 36 56 123 P34457 3.86e-29 Putative uncharacterized transposon-derived protein F54H12.3 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0015074 33727 XM_029334717.2 3115 2841 1479 3046 1036 Q01887 5.54e-113 Tyrosine-protein kinase RYK (EC 2.7.10.1) (Kinase VIK) (Met-related kinase) (NYK-R) Mus musculus (Mouse) axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cell proliferation in midbrain [GO:0033278]; chemorepulsion of axon [GO:0061643]; chemorepulsion of dopaminergic neuron axon [GO:0036518]; commissural neuron axon guidance [GO:0071679]; corpus callosum development [GO:0022038]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative chemotaxis [GO:0050919]; negative regulation of axon extension involved in axon guidance [GO:0048843]; neuron differentiation [GO:0030182]; neuron projection development [GO:0031175]; planar cell polarity pathway involved in axon guidance [GO:1904938]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; protein phosphorylation [GO:0006468]; skeletal system morphogenesis [GO:0048705]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953] GO:0004672; GO:0004888; GO:0005109; GO:0005524; GO:0005634; GO:0005737; GO:0005886; GO:0006468; GO:0007169; GO:0007409; GO:0007411; GO:0016020; GO:0016055; GO:0017147; GO:0022038; GO:0030182; GO:0031175; GO:0033278; GO:0033674; GO:0036518; GO:0042813; GO:0043235; GO:0043410; GO:0048705; GO:0048843; GO:0048846; GO:0050919; GO:0061643; GO:0071679; GO:1904938; GO:1904948; GO:1904953 33728 XM_029341209.2 141 151 59 377 315 P41969 2.89e-26 ETS domain-containing protein Elk-1 Mus musculus (Mouse) cell differentiation [GO:0030154]; cellular response to gamma radiation [GO:0071480]; cellular response to lipid [GO:0071396]; cellular response to testosterone stimulus [GO:0071394]; gene expression [GO:0010467]; liver development [GO:0001889]; lung development [GO:0030324]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of neuron death [GO:1901216]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; response to fibroblast growth factor [GO:0071774]; response to light stimulus [GO:0009416] GO:0000976; GO:0000978; GO:0000981; GO:0001228; GO:0001889; GO:0003682; GO:0003690; GO:0003700; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0006355; GO:0006357; GO:0009416; GO:0010467; GO:0030154; GO:0030324; GO:0030374; GO:0030425; GO:0043025; GO:0043679; GO:0045893; GO:0045944; GO:0061629; GO:0071394; GO:0071396; GO:0071480; GO:0071774; GO:1901216; GO:1990837 33729 XM_029324009.2 45 0 5 0 8 NA NA NA NA NA NA 33730 XM_029335406.2 16618 20672 13456 8160 12240 NA NA NA NA NA NA 33731 XM_044319273.1 85 20 44 12 135 NA NA NA NA NA NA 33732 XR_006393642.1 19 0 10 0 20 NA NA NA NA NA NA 33733 XM_044321057.1 109 65 20 65 63 Q5E9T7 1.96e-116 Protein Jade-1 (Jade family PHD finger protein 1) (PHD finger protein 17) Bos taurus (Bovine) apoptotic process [GO:0006915]; histone modification [GO:0016570]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000123; GO:0005634; GO:0005737; GO:0005856; GO:0006357; GO:0006915; GO:0016570; GO:0042995; GO:0046872 33734 XM_029354185.2 12 0 9 6 0 NA NA NA NA NA NA 33735 XM_029337444.2 0 4 0 23 0 Q9DCV4 1.12e-69 Regulator of microtubule dynamics protein 1 (RMD-1) (mRMD-1) (Microtubule-associated protein) (Protein FAM82B) Mus musculus (Mouse) NA GO:0005737; GO:0005739; GO:0005876; GO:0008017; GO:0097431 33736 XM_044321470.1 125 18 216 102 292 NA NA NA NA NA NA 33737 XR_006393946.1 9 0 6 0 194 NA NA NA NA NA NA 33738 XR_006391997.1 9 0 0 0 0 NA NA NA NA NA NA 33739 XM_029356039.2 235 123 0 90 237 NA NA NA NA NA NA 33740 XM_044326387.1 3481 1612 2203 5404 2343 Q90413 4.09e-74 Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) Danio rerio (Zebrafish) (Brachydanio rerio) fibroblast growth factor receptor signaling pathway [GO:0008543]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of kinase activity [GO:0033674]; regulation of bile acid biosynthetic process [GO:0070857]; regulation of hematopoietic stem cell differentiation [GO:1902036]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0004714; GO:0005007; GO:0005524; GO:0005768; GO:0005783; GO:0005886; GO:0007169; GO:0008543; GO:0017134; GO:0033674; GO:0043235; GO:0070374; GO:0070857; GO:1902036 33741 XR_006395051.1 1002 726 758 1194 717 A9ZSY3 1.51e-85 Facilitated trehalose transporter Tret1 (BmTRET1) Bombyx mori (Silk moth) trehalose transport [GO:0015771] GO:0005886; GO:0015574; GO:0015771; GO:0051119 33742 XR_006395051.1 1002 726 758 1194 717 A9ZSY3 1.51e-85 Facilitated trehalose transporter Tret1 (BmTRET1) Bombyx mori (Silk moth) trehalose transport [GO:0015771] GO:0005886; GO:0015574; GO:0015771; GO:0051119 33743 XM_029332077.2 480 281 190 377 340 NA NA NA NA NA NA 33744 XR_006392558.1 10 3 54 4 100 NA NA NA NA NA NA 33745 XM_029339549.2 1995 1589 1071 1544 1753 P20650 3.97e-139 Protein phosphatase 1A (EC 3.1.3.16) (Protein phosphatase 2C isoform alpha) (PP2C-alpha) (Protein phosphatase IA) Rattus norvegicus (Rat) cellular response to transforming growth factor beta stimulus [GO:0071560]; dephosphorylation [GO:0016311]; N-terminal protein myristoylation [GO:0006499]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of SMAD protein complex assembly [GO:0010991]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of protein export from nucleus [GO:0046827]; protein dephosphorylation [GO:0006470]; protein export from nucleus [GO:0006611] GO:0000287; GO:0004721; GO:0004722; GO:0005634; GO:0005829; GO:0006470; GO:0006499; GO:0006611; GO:0008022; GO:0010991; GO:0016020; GO:0016311; GO:0017018; GO:0030145; GO:0030512; GO:0030514; GO:0033192; GO:0035970; GO:0043005; GO:0043124; GO:0044325; GO:0045893; GO:0046827; GO:0070412; GO:0071560; GO:0090263; GO:1901223 33746 XM_029350419.2 1485 1018 755 970 1202 O14802 0 DNA-directed RNA polymerase III subunit RPC1 (RNA polymerase III subunit C1) (EC 2.7.7.6) (DNA-directed RNA polymerase III largest subunit) (DNA-directed RNA polymerase III subunit A) (RNA polymerase III 155 kDa subunit) (RPC155) (RNA polymerase III subunit C160) Homo sapiens (Human) defense response to virus [GO:0051607]; DNA-templated transcription [GO:0006351]; innate immune response [GO:0045087]; positive regulation of interferon-beta production [GO:0032728] GO:0003677; GO:0003682; GO:0003899; GO:0005634; GO:0005654; GO:0005666; GO:0005829; GO:0006351; GO:0016020; GO:0032728; GO:0045087; GO:0046872; GO:0051607 33747 XM_029348457.2 154 76 132 165 227 Q5M8G4 7.96e-23 Leucine-rich repeat-containing protein 40 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA NA 33748 XM_044326843.1 0 0 7 0 8 NA NA NA NA NA NA 33749 XM_044324539.1 3 2 23 40 99 NA NA NA NA NA NA 33750 XM_029355133.2 0 0 0 647 560 NA NA NA NA NA NA 33751 XM_029341620.2 2162 1386 1012 1619 1846 P67963 0 Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1) Xenopus laevis (African clawed frog) cell cycle [GO:0007049]; cell division [GO:0051301]; intermediate filament cytoskeleton organization [GO:0045104]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; protein phosphorylation [GO:0006468]; Wnt signaling pathway [GO:0016055] GO:0000776; GO:0004674; GO:0005524; GO:0005737; GO:0005819; GO:0006468; GO:0007049; GO:0016055; GO:0016607; GO:0036064; GO:0045104; GO:0051301; GO:0106310; GO:1900226 33752 XR_006395945.1 0 0 8 1 0 NA NA NA NA NA NA 33753 XM_044323580.1 138 159 53 48 160 NA NA NA NA NA NA 33754 XM_044322276.1 18 0 0 31 4 NA NA NA NA NA NA 33755 XM_029344680.2 284 1008 244 182 256 Q9CYL5 1.97e-24 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Mus musculus (Mouse) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070374 33756 XM_044318479.1 0 5 72 554 290 Q28824 2.25e-98 Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form] Bos taurus (Bovine) protein phosphorylation [GO:0006468]; tonic smooth muscle contraction [GO:0014820] GO:0001725; GO:0003779; GO:0004672; GO:0004687; GO:0005516; GO:0005524; GO:0005737; GO:0006468; GO:0014820; GO:0030027; GO:0032154; GO:0046872 33757 XM_029323526.2 13053 16729 8068 11702 6321 Q9EQX4 2.15e-36 Allograft inflammatory factor 1-like (Ionized calcium-binding adapter molecule 2) Mus musculus (Mouse) actin filament bundle assembly [GO:0051017]; ruffle assembly [GO:0097178] GO:0005509; GO:0005737; GO:0005884; GO:0005925; GO:0015629; GO:0032587; GO:0032991; GO:0051015; GO:0051017; GO:0097178 33758 XM_029338210.2 0 6 13 16 4 NA NA NA NA NA NA 33759 XM_029337846.2 719 269 209 68 193 NA NA NA NA NA NA 33760 XM_029351403.2 8 0 0 0 0 P34410 2.5e-25 TWiK family of potassium channels protein 7 Caenorhabditis elegans potassium ion transmembrane transport [GO:0071805]; stabilization of membrane potential [GO:0030322] GO:0005886; GO:0015271; GO:0022841; GO:0030322; GO:0071805 33761 XM_029358426.2 28 0 92 0 67 Q708S6 9.14e-41 Acid-sensing ion channel 1C (ASIC1-C) (Acid-sensing ion channel 1.3-C) (Amiloride-sensitive cation channel 2-C, neuronal-C) (ZASIC1.3) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to pH [GO:0071467]; protein homotrimerization [GO:0070207]; sodium ion transmembrane transport [GO:0035725] GO:0005261; GO:0005886; GO:0015280; GO:0035725; GO:0044736; GO:0070207; GO:0071467 33762 XM_044326446.1 12 3 4 31 9 NA NA NA NA NA NA 33763 XM_029337203.2 95 86 108 106 17 NA NA NA NA NA NA 33764 XM_044319480.1 1 13 9 29 12 Q09575 7.88e-32 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 33765 XM_044320031.1 54 3 444 37 73 NA NA NA NA NA NA 33766 XR_006396367.1 13 0 24 1 89 NA NA NA NA NA NA 33767 XM_044316882.1 337 44 196 220 492 P46869 1.07e-65 Kinesin-like protein FLA10 (Protein KHP1) Chlamydomonas reinhardtii (Chlamydomonas smithii) intraciliary anterograde transport [GO:0035720]; motile cilium assembly [GO:0044458] GO:0003777; GO:0005524; GO:0005874; GO:0005929; GO:0008017; GO:0031514; GO:0035720; GO:0036064; GO:0044458; GO:0097014 33768 XM_044313671.1 85 12 68 14 274 NA NA NA NA NA NA 33769 XM_029344445.2 0 0 94 153 147 Q9H9Q4 2.95e-22 Non-homologous end-joining factor 1 (Protein cernunnos) (XRCC4-like factor) Homo sapiens (Human) B cell differentiation [GO:0030183]; central nervous system development [GO:0007417]; DNA ligation involved in DNA repair [GO:0051103]; double-strand break repair via nonhomologous end joining [GO:0006303]; immunoglobulin V(D)J recombination [GO:0033152]; positive regulation of ligase activity [GO:0051351]; response to ionizing radiation [GO:0010212]; T cell differentiation [GO:0030217] GO:0001650; GO:0005634; GO:0005654; GO:0006303; GO:0007417; GO:0010212; GO:0030183; GO:0030217; GO:0032807; GO:0033152; GO:0035861; GO:0045027; GO:0051103; GO:0051351; GO:0070182; GO:0070419 33770 XM_044323381.1 24 12 13 45 40 B8UU78 0 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 33771 XM_044308916.1 6 7 0 0 9 NA NA NA NA NA NA 33772 XM_029358357.2 27 0 0 95 39 Q3KP44 3.16e-63 Ankyrin repeat domain-containing protein 55 Homo sapiens (Human) NA NA 33773 XM_044324602.1 0 6 6 1 29 NA NA NA NA NA NA 33774 XM_044321931.1 4 2 10 32 25 NA NA NA NA NA NA 33775 XR_003824504.2 0 0 0 80 263 NA NA NA NA NA NA 33776 XM_029338040.2 34237 25798 9039 16595 11894 NA NA NA NA NA NA 33777 XM_029339624.2 0 0 0 0 13 Q9Y394 3.37e-85 Dehydrogenase/reductase SDR family member 7 (EC 1.1.1.-) (Retinal short-chain dehydrogenase/reductase 4) (retSDR4) (Short chain dehydrogenase/reductase family 34C member 1) (Protein SDR34C1) Homo sapiens (Human) NA GO:0004090; GO:0005789; GO:0016020; GO:0016616; GO:0052650 33778 XM_029338359.2 0 25 0 0 0 Q96F81 0 Protein dispatched homolog 1 Homo sapiens (Human) determination of left/right symmetry [GO:0007368]; diaphragm development [GO:0060539]; dorsal/ventral pattern formation [GO:0009953]; embryonic pattern specification [GO:0009880]; patched ligand maturation [GO:0007225]; peptide transport [GO:0015833]; protein homotrimerization [GO:0070207]; regulation of protein secretion [GO:0050708]; smoothened signaling pathway [GO:0007224]; transmembrane transport [GO:0055085] GO:0007224; GO:0007225; GO:0007368; GO:0009880; GO:0009953; GO:0015833; GO:0016020; GO:0016323; GO:0022857; GO:0050708; GO:0055085; GO:0060539; GO:0070207; GO:1904680 33779 XM_029324813.2 1576 1808 980 488 417 NA NA NA NA NA NA 33780 XM_029353982.2 2682 2319 1529 2529 2468 Q7T292 2.21e-109 Mitoferrin-2 (Mitochondrial iron transporter 2) (Solute carrier family 25 member 28) Danio rerio (Zebrafish) (Brachydanio rerio) iron import into the mitochondrion [GO:0048250]; iron ion homeostasis [GO:0055072] GO:0005743; GO:0015093; GO:0031966; GO:0048250; GO:0055072 33781 XM_029356718.2 1788 1808 1191 1400 1236 Q58DG1 4.16e-144 MYG1 exonuclease (EC 3.1.-.-) Bos taurus (Bovine) locomotory exploration behavior [GO:0035641] GO:0004518; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005739; GO:0005759; GO:0035641 33782 XM_029342656.2 1358 1174 691 1067 1272 Q9R0N9 2.26e-42 Synaptotagmin-9 (Synaptotagmin IX) (SytIX) (Synaptotagmin V) Mus musculus (Mouse) calcium-dependent activation of synaptic vesicle fusion [GO:0099502]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of insulin secretion [GO:0050796]; vesicle-mediated transport [GO:0016192] GO:0000149; GO:0001786; GO:0005509; GO:0005544; GO:0005546; GO:0005886; GO:0014059; GO:0016192; GO:0017156; GO:0017158; GO:0019905; GO:0030141; GO:0030276; GO:0030667; GO:0030672; GO:0031045; GO:0042802; GO:0045956; GO:0050796; GO:0070382; GO:0071277; GO:0098686; GO:0099502 33783 XM_044327183.1 0 6 0 0 25 NA NA NA NA NA NA 33784 XM_044310670.1 8 7 8 0 2 NA NA NA NA NA NA 33785 XM_044316314.1 3 2 2 45 107 P0CT39 2.75e-87 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 33786 XM_029358630.2 16 67 46 143 208 Q80W54 0 CAAX prenyl protease 1 homolog (EC 3.4.24.84) (Farnesylated proteins-converting enzyme 1) (FACE-1) (Prenyl protein-specific endoprotease 1) (Zinc metalloproteinase Ste24 homolog) Mus musculus (Mouse) adult walking behavior [GO:0007628]; bone mineralization [GO:0030282]; CAAX-box protein processing [GO:0071586]; calcium ion import into sarcoplasmic reticulum [GO:1990036]; CAMKK-AMPK signaling cascade [GO:0061762]; cardiac conduction [GO:0061337]; cardiac muscle cell development [GO:0055013]; cardiac ventricle development [GO:0003231]; cellular lipid metabolic process [GO:0044255]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; chromatin organization [GO:0006325]; chromosome organization [GO:0051276]; determination of adult lifespan [GO:0008340]; DNA repair [GO:0006281]; epidermis development [GO:0008544]; growth plate cartilage development [GO:0003417]; hair follicle development [GO:0001942]; heart morphogenesis [GO:0003007]; histone H2B acetylation [GO:0043969]; histone H2B-K5 acetylation [GO:0043979]; hypomethylation of CpG island [GO:0044029]; inflammatory cell apoptotic process [GO:0006925]; kidney morphogenesis [GO:0060993]; liver development [GO:0001889]; maintenance of rDNA [GO:0043007]; multicellular organism growth [GO:0035264]; negative regulation of gene expression [GO:0010629]; negative regulation of miRNA maturation [GO:1903799]; neuromuscular process [GO:0050905]; nuclear envelope organization [GO:0006998]; nucleus organization [GO:0006997]; positive regulation of gene expression [GO:0010628]; prenylated protein catabolic process [GO:0030327]; protein processing [GO:0016485]; regulation of autophagy [GO:0010506]; regulation of blood circulation [GO:1903522]; regulation of bone mineralization [GO:0030500]; regulation of cell shape [GO:0008360]; regulation of cellular senescence [GO:2000772]; regulation of defense response to virus [GO:0050688]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of DNA methylation [GO:0044030]; regulation of DNA-templated transcription [GO:0006355]; regulation of fibroblast proliferation [GO:0048145]; regulation of glucose metabolic process [GO:0010906]; regulation of heart contraction [GO:0008016]; regulation of histone H4 acetylation [GO:0090239]; regulation of histone H4-K16 acetylation [GO:2000618]; regulation of hormone metabolic process [GO:0032350]; regulation of lipid metabolic process [GO:0019216]; regulation of mitotic cell cycle [GO:0007346]; regulation of mitotic cell cycle DNA replication [GO:1903463]; regulation of multicellular organism growth [GO:0040014]; regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903025]; regulation of stress-activated protein kinase signaling cascade [GO:0070302]; regulation of termination of RNA polymerase I transcription [GO:2000730]; regulation of TOR signaling [GO:0032006]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; response to DNA damage checkpoint signaling [GO:0072423]; thymus development [GO:0048538]; ventricular cardiac muscle tissue development [GO:0003229] GO:0001889; GO:0001942; GO:0003007; GO:0003229; GO:0003231; GO:0003417; GO:0003690; GO:0004175; GO:0004222; GO:0005635; GO:0005637; GO:0005789; GO:0006281; GO:0006325; GO:0006355; GO:0006925; GO:0006974; GO:0006997; GO:0006998; GO:0007346; GO:0007628; GO:0008016; GO:0008340; GO:0008360; GO:0008544; GO:0010506; GO:0010628; GO:0010629; GO:0010906; GO:0016020; GO:0016485; GO:0019216; GO:0030282; GO:0030327; GO:0030500; GO:0032006; GO:0032350; GO:0032991; GO:0035264; GO:0040014; GO:0043007; GO:0043516; GO:0043969; GO:0043979; GO:0044029; GO:0044030; GO:0044255; GO:0046872; GO:0048145; GO:0048538; GO:0050688; GO:0050905; GO:0051276; GO:0055013; GO:0060307; GO:0060993; GO:0061337; GO:0061762; GO:0070302; GO:0071480; GO:0071586; GO:0072423; GO:0090239; GO:1903025; GO:1903463; GO:1903522; GO:1903799; GO:1990036; GO:2000618; GO:2000730; GO:2000772 33787 XM_044327079.1 298 161 224 560 517 NA NA NA NA NA NA 33788 XM_044323608.1 72 30 35 143 111 Q9UFW8 5.27e-26 CGG triplet repeat-binding protein 1 (CGG-binding protein 1) (20 kDa CGG-binding protein) (p20-CGGBP DNA-binding protein) Homo sapiens (Human) epigenetic regulation of gene expression [GO:0040029]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of gene expression [GO:0010468] GO:0000122; GO:0003690; GO:0005634; GO:0005654; GO:0010468; GO:0040029; GO:0042802; GO:0140297 33789 XM_029333081.2 396 363 367 380 513 A7RQM5 0 ATPase ASNA1 homolog (EC 3.6.-.-) (Arsenical pump-driving ATPase homolog) (Arsenite-stimulated ATPase) Nematostella vectensis (Starlet sea anemone) post-translational protein targeting to endoplasmic reticulum membrane [GO:0006620]; protein insertion into ER membrane [GO:0045048] GO:0005524; GO:0006620; GO:0016887; GO:0043529; GO:0045048; GO:0046872 33790 XM_029345905.2 136 1 1 106 14 NA NA NA NA NA NA 33791 XR_006395010.1 13 20 17 28 45 NA NA NA NA NA NA 33792 XM_044324532.1 13 0 7 4 77 NA NA NA NA NA NA 33793 XM_029344937.2 26 16 20 33 22 NA NA NA NA NA NA 33794 XM_029342115.2 7 6 13 5 50 NA NA NA NA NA NA 33795 XR_006395711.1 891 1515 744 729 275 NA NA NA NA NA NA 33796 XM_029358455.2 3 24 10 17 37 Q05941 1.17e-80 Neuronal acetylcholine receptor subunit alpha-7 Rattus norvegicus (Rat) acetylcholine receptor signaling pathway [GO:0095500]; associative learning [GO:0008306]; B cell activation [GO:0042113]; behavioral response to ethanol [GO:0048149]; behavioral response to nicotine [GO:0035095]; calcium ion transport [GO:0006816]; cation transmembrane transport [GO:0098655]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; cognition [GO:0050890]; dendrite arborization [GO:0140059]; dendritic spine organization [GO:0097061]; dopamine biosynthetic process [GO:0042416]; endocytosis [GO:0006897]; establishment of localization in cell [GO:0051649]; excitatory postsynaptic potential [GO:0060079]; flagellated sperm motility [GO:0030317]; generation of ovulation cycle rhythm [GO:0060112]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; learning or memory [GO:0007611]; membrane depolarization [GO:0051899]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; modulation of excitatory postsynaptic potential [GO:0098815]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of tumor necrosis factor production [GO:0032720]; nervous system process [GO:0050877]; neuronal action potential [GO:0019228]; ovulation cycle [GO:0042698]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of CoA-transferase activity [GO:1905920]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure [GO:0001988]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of amyloid fibril formation [GO:1905906]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of inflammatory response [GO:0050727]; regulation of membrane potential [GO:0042391]; regulation of neuron death [GO:1901214]; regulation of nitric oxide metabolic process [GO:0080164]; regulation of norepinephrine secretion [GO:0014061]; regulation of response to drug [GO:2001023]; regulation of synaptic transmission, dopaminergic [GO:0032225]; response to acetylcholine [GO:1905144]; response to amyloid-beta [GO:1904645]; response to carbamate [GO:0046681]; response to cold [GO:0009409]; response to ethanol [GO:0045471]; response to food [GO:0032094]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; sensory processing [GO:0050893]; signal transduction [GO:0007165]; synapse organization [GO:0050808]; synaptic transmission, cholinergic [GO:0007271]; T cell activation [GO:0042110] GO:0001540; GO:0001666; GO:0001933; GO:0001934; GO:0001988; GO:0005216; GO:0005231; GO:0005737; GO:0005886; GO:0005892; GO:0006811; GO:0006816; GO:0006874; GO:0006897; GO:0007165; GO:0007268; GO:0007271; GO:0007611; GO:0007613; GO:0008179; GO:0008284; GO:0008306; GO:0009409; GO:0009897; GO:0010628; GO:0014061; GO:0014069; GO:0015464; GO:0015643; GO:0016020; GO:0016324; GO:0017081; GO:0019228; GO:0019901; GO:0022848; GO:0030317; GO:0030424; GO:0030425; GO:0030426; GO:0030594; GO:0030673; GO:0032094; GO:0032225; GO:0032279; GO:0032691; GO:0032715; GO:0032720; GO:0033138; GO:0034220; GO:0035094; GO:0035095; GO:0042110; GO:0042113; GO:0042166; GO:0042391; GO:0042416; GO:0042698; GO:0042734; GO:0042803; GO:0043005; GO:0043025; GO:0043197; GO:0043198; GO:0043410; GO:0044853; GO:0045121; GO:0045202; GO:0045211; GO:0045471; GO:0045766; GO:0046681; GO:0048149; GO:0050727; GO:0050728; GO:0050804; GO:0050808; GO:0050877; GO:0050890; GO:0050893; GO:0051117; GO:0051247; GO:0051649; GO:0051899; GO:0060079; GO:0060112; GO:0070373; GO:0070374; GO:0080164; GO:0095500; GO:0097061; GO:0097110; GO:0098655; GO:0098690; GO:0098815; GO:0098897; GO:0098981; GO:0099171; GO:0099634; GO:0140059; GO:1900273; GO:1901214; GO:1902004; GO:1902430; GO:1902991; GO:1904315; GO:1904645; GO:1905144; GO:1905906; GO:1905920; GO:2000463; GO:2001023 33797 XR_006391871.1 18 0 12 14 19 Q3UQ28 2.3e-29 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 33798 XR_006391871.1 18 0 12 14 19 Q3UQ28 8.53e-27 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 33799 XR_006395517.1 297 106 41 119 24 NA NA NA NA NA NA 33800 XM_044321440.1 125 0 0 75 0 Q7T163 0 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 33801 XM_044321440.1 125 0 0 75 0 Q7T163 4.03e-42 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 33802 XM_044321440.1 125 0 0 75 0 Q7T163 3.84e-33 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 33803 XM_044321440.1 125 0 0 75 0 Q7T163 2.52e-29 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 33804 XM_044321440.1 125 0 0 75 0 Q7T163 6.33e-27 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 33805 XM_044321440.1 125 0 0 75 0 Q7T163 1.28e-22 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 33806 XM_029345112.2 26 22 16 20 47 NA NA NA NA NA NA 33807 XR_006391952.1 6 0 1 0 0 NA NA NA NA NA NA 33808 XM_029355654.2 151 44 51 94 163 P43141 1.1e-26 Beta-4C adrenergic receptor (Beta-4C adrenoreceptor) (Beta-4C adrenoceptor) Meleagris gallopavo (Wild turkey) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; positive regulation of heart contraction [GO:0045823] GO:0004940; GO:0005886; GO:0007189; GO:0045823 33809 XR_006396696.1 1530 985 613 747 826 NA NA NA NA NA NA 33810 XM_029353210.2 10 0 0 0 0 Q96DM1 7.55e-63 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 33811 XM_044307397.1 158 176 86 104 60 NA NA NA NA NA NA 33812 XM_029332525.2 1457 1074 503 477 364 NA NA NA NA NA NA 33813 XM_044325343.1 0 0 0 100 102 P07911 6.11e-23 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Homo sapiens (Human) antibacterial innate immune response [GO:0140367]; apoptotic signaling pathway [GO:0097190]; autophagy [GO:0006914]; cellular calcium ion homeostasis [GO:0006874]; cellular chloride ion homeostasis [GO:0030644]; cellular defense response [GO:0006968]; cellular phosphate ion homeostasis [GO:0030643]; cellular response to unfolded protein [GO:0034620]; cellular sodium ion homeostasis [GO:0006883]; chaperone-mediated protein folding [GO:0061077]; citric acid secretion [GO:0046720]; collecting duct development [GO:0072044]; connective tissue replacement [GO:0097709]; creatinine homeostasis [GO:0097273]; defense response to Gram-negative bacterium [GO:0050829]; endoplasmic reticulum organization [GO:0007029]; glomerular filtration [GO:0003094]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; juxtaglomerular apparatus development [GO:0072051]; leukocyte cell-cell adhesion [GO:0007159]; lipid metabolic process [GO:0006629]; metanephric ascending thin limb development [GO:0072218]; metanephric distal convoluted tubule development [GO:0072221]; metanephric thick ascending limb development [GO:0072233]; micturition [GO:0060073]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell population proliferation [GO:0008285]; neutrophil migration [GO:1990266]; organ or tissue specific immune response [GO:0002251]; peptidyl-threonine phosphorylation [GO:0018107]; potassium ion homeostasis [GO:0055075]; protein localization to vacuole [GO:0072665]; protein transport into plasma membrane raft [GO:0044861]; regulation of blood pressure [GO:0008217]; regulation of protein transport [GO:0051223]; regulation of urine volume [GO:0035809]; renal sodium ion absorption [GO:0070294]; renal urate salt excretion [GO:0097744]; renal water homeostasis [GO:0003091]; response to lipopolysaccharide [GO:0032496]; response to water deprivation [GO:0009414]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; ubiquitin-dependent ERAD pathway [GO:0030433]; urate transport [GO:0015747]; urea transmembrane transport [GO:0071918] GO:0000922; GO:0002251; GO:0003091; GO:0003094; GO:0005201; GO:0005509; GO:0005615; GO:0005783; GO:0005796; GO:0005929; GO:0006629; GO:0006874; GO:0006883; GO:0006914; GO:0006954; GO:0006968; GO:0007029; GO:0007157; GO:0007159; GO:0008217; GO:0008285; GO:0008380; GO:0009410; GO:0009414; GO:0009986; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0018107; GO:0019864; GO:0019898; GO:0030433; GO:0030643; GO:0030644; GO:0032496; GO:0033209; GO:0033555; GO:0034620; GO:0035809; GO:0044861; GO:0046720; GO:0050829; GO:0051223; GO:0055075; GO:0060073; GO:0060170; GO:0061077; GO:0070062; GO:0070294; GO:0071918; GO:0072044; GO:0072051; GO:0072218; GO:0072221; GO:0072233; GO:0072665; GO:0097190; GO:0097273; GO:0097709; GO:0097744; GO:0140367; GO:1990266 33814 XM_044307517.1 0 0 1 0 24 NA NA NA NA NA NA 33815 XR_006395367.1 208 123 47 470 305 NA NA NA NA NA NA 33816 XM_029334150.2 2077 1817 1848 2152 1687 NA NA NA NA NA NA 33817 XM_029337921.2 2327 1565 824 1315 1276 NA NA NA NA NA NA 33818 XM_044320400.1 0 27 0 9 14 NA NA NA NA NA NA 33819 XM_044316894.1 41 86 52 0 0 P07314 3.35e-110 Glutathione hydrolase 1 proenzyme (EC 3.4.19.13) (Gamma-glutamyltransferase 1) (Gamma-glutamyltranspeptidase 1) (GGT 1) (EC 2.3.2.2) (Leukotriene-C4 hydrolase) (EC 3.4.19.14) (CD antigen CD224) [Cleaved into: Glutathione hydrolase 1 heavy chain; Glutathione hydrolase 1 light chain] Rattus norvegicus (Rat) aging [GO:0007568]; amino acid metabolic process [GO:0006520]; cellular response to oxidative stress [GO:0034599]; cysteine biosynthetic process [GO:0019344]; fatty acid metabolic process [GO:0006631]; glutamate metabolic process [GO:0006536]; glutathione biosynthetic process [GO:0006750]; glutathione catabolic process [GO:0006751]; hepatoblast differentiation [GO:0061017]; hepatocyte differentiation [GO:0070365]; leukotriene D4 biosynthetic process [GO:1901750]; leukotriene metabolic process [GO:0006691]; liver regeneration [GO:0097421]; peptide modification [GO:0031179]; proteolysis [GO:0006508]; regulation of immune system process [GO:0002682]; regulation of inflammatory response [GO:0050727]; response to alcohol [GO:0097305]; response to estradiol [GO:0032355]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]; spermatogenesis [GO:0007283]; zymogen activation [GO:0031638] GO:0000048; GO:0002682; GO:0002951; GO:0005615; GO:0005886; GO:0006508; GO:0006520; GO:0006536; GO:0006631; GO:0006691; GO:0006750; GO:0006751; GO:0007283; GO:0007568; GO:0016755; GO:0019344; GO:0031179; GO:0031638; GO:0031982; GO:0032355; GO:0032496; GO:0034599; GO:0034612; GO:0036374; GO:0050727; GO:0061017; GO:0070365; GO:0097305; GO:0097421; GO:0102953; GO:0103068; GO:1901750 33820 XR_006392935.1 41 2 25 5 151 NA NA NA NA NA NA 33821 XM_044325003.1 205 93 68 48 124 Q96AY4 1.51e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33822 XM_044325003.1 205 93 68 48 124 Q96AY4 5.8e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33823 XM_044325003.1 205 93 68 48 124 Q96AY4 2.67e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33824 XM_044325003.1 205 93 68 48 124 Q96AY4 2.53e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33825 XM_044325003.1 205 93 68 48 124 Q96AY4 2.58e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33826 XM_044325003.1 205 93 68 48 124 Q96AY4 2.88e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33827 XM_044325003.1 205 93 68 48 124 Q96AY4 7.87e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33828 XM_044325003.1 205 93 68 48 124 Q96AY4 5.33e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33829 XM_044323845.1 1795 558 1283 1833 1431 O57683 0 Splicing factor 3B subunit 1 (146 kDa nuclear protein) (Pre-mRNA-splicing factor SF3b 155 kDa subunit) (SF3b155) (Spliceosome-associated protein 155) (SAP 155) Xenopus laevis (African clawed frog) spliceosomal complex assembly [GO:0000245] GO:0000245; GO:0003729; GO:0005634; GO:0005681 33830 XR_006394355.1 1 0 9 48 104 NA NA NA NA NA NA 33831 XM_044311577.1 616 385 344 575 714 Q9H999 5.47e-133 Pantothenate kinase 3 (hPanK3) (EC 2.7.1.33) (Pantothenic acid kinase 3) Homo sapiens (Human) coenzyme A biosynthetic process [GO:0015937]; phosphorylation [GO:0016310] GO:0004594; GO:0005524; GO:0005634; GO:0005829; GO:0015937; GO:0016310; GO:0019842; GO:0042803; GO:1905502 33832 XR_003825069.2 6 2 13 10 15 NA NA NA NA NA NA 33833 XM_044324460.1 35 0 0 0 0 NA NA NA NA NA NA 33834 XR_006396853.1 29 31 11 0 8 NA NA NA NA NA NA 33835 XR_003824336.2 49 20 39 10 115 NA NA NA NA NA NA 33836 XM_044316472.1 0 0 10 0 0 NA NA NA NA NA NA 33837 XM_044324616.1 1 0 0 0 9 NA NA NA NA NA NA 33838 XM_029335183.2 119 34 0 49 28 C3YWU0 1.76e-169 Alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucoside fucohydrolase) Branchiostoma floridae (Florida lancelet) (Amphioxus) fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139] GO:0004560; GO:0005576; GO:0005764; GO:0006004; GO:0016139 33839 XM_044328248.1 0 0 6 19 0 NA NA NA NA NA NA 33840 XM_029330015.2 51 0 4 0 93 Q9Y2M2 3.18e-72 Protein SSUH2 homolog (Protein ssu-2 homolog) Homo sapiens (Human) odontogenesis [GO:0042476] GO:0005634; GO:0005737; GO:0031072; GO:0042476; GO:0051082 33841 XM_029339555.2 546 494 364 323 300 NA NA NA NA NA NA 33842 XR_006395964.1 82 19 14 25 17 NA NA NA NA NA NA 33843 XM_029334930.2 57 461 5 9 970 NA NA NA NA NA NA 33844 XM_044310000.1 0 0 2 0 13 NA NA NA NA NA NA 33845 XR_006393504.1 5 35 33 101 59 NA NA NA NA NA NA 33846 XM_044317524.1 11 10 11 3 6 Q7TN88 1.98e-59 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 33847 XM_044317524.1 11 10 11 3 6 Q7TN88 1.1e-42 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 33848 XM_044322147.1 0 18 0 0 18 Q9DCC4 1.74e-75 Pyrroline-5-carboxylate reductase 3 (P5C reductase 3) (P5CR 3) (EC 1.5.1.2) (Pyrroline-5-carboxylate reductase-like protein) Mus musculus (Mouse) cytidine deamination [GO:0009972]; L-proline biosynthetic process [GO:0055129] GO:0004126; GO:0004735; GO:0005829; GO:0009972; GO:0045171; GO:0055129; GO:0072686 33849 XM_044310383.1 0 0 0 0 7 NA NA NA NA NA NA 33850 XM_044317382.1 49 13 59 8 67 NA NA NA NA NA NA 33851 XM_044309412.1 1 0 8 0 1 NA NA NA NA NA NA 33852 XM_029346525.2 125 0 31 110 0 Q9I8C7 7.29e-93 Neuronal acetylcholine receptor subunit alpha-10 (Alpha 10 nAChR) (Nicotinic acetylcholine receptor subunit alpha-10) (NACHR alpha-10) Gallus gallus (Chicken) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; response to auditory stimulus [GO:0010996]; signal transduction [GO:0007165] GO:0004888; GO:0005231; GO:0005262; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0010996; GO:0022848; GO:0030594; GO:0034220; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051899; GO:1904315 33853 XR_006395418.1 15 37 39 52 18 NA NA NA NA NA NA 33854 XM_044324315.1 55 65 49 69 140 Q96MB7 2.93e-44 Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease) Homo sapiens (Human) NA GO:0004518; GO:0005634; GO:0005829; GO:0005886; GO:0034451; GO:0046872 33855 XM_044324315.1 55 65 49 69 140 Q96MB7 2.93e-44 Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease) Homo sapiens (Human) NA GO:0004518; GO:0005634; GO:0005829; GO:0005886; GO:0034451; GO:0046872 33856 XM_029327285.2 283 16 87 26 103 Q6NZ04 3.04e-117 Homeobox protein six1b (Homeobox protein six1a) (Sine oculis homeobox homolog 1a) (Sine oculis homeobox homolog 1b) Danio rerio (Zebrafish) (Brachydanio rerio) adenohypophysis development [GO:0021984]; apoptotic process [GO:0006915]; extraocular skeletal muscle development [GO:0002074]; inner ear development [GO:0048839]; peripheral nervous system neuron development [GO:0048935]; pharyngeal muscle development [GO:0043282]; regulation of skeletal muscle cell proliferation [GO:0014857]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal muscle fiber development [GO:0048741]; striated muscle cell differentiation [GO:0051146] GO:0000978; GO:0000981; GO:0002074; GO:0005634; GO:0005667; GO:0005737; GO:0006357; GO:0006915; GO:0014857; GO:0021984; GO:0043282; GO:0048741; GO:0048839; GO:0048935; GO:0051146 33857 XM_029338295.2 10969 9656 4794 8373 5438 Q6P5H6 1.91e-95 FERM domain-containing protein 5 Mus musculus (Mouse) actomyosin structure organization [GO:0031032]; negative regulation of cell motility [GO:2000146]; positive regulation of cell adhesion [GO:0045785]; regulation of cell migration [GO:0030334] GO:0005178; GO:0005856; GO:0005912; GO:0008092; GO:0019901; GO:0030334; GO:0031032; GO:0045785; GO:2000146 33858 XM_029340874.2 4869 4575 3669 9041 9098 P55196 0 Afadin (ALL1-fused gene from chromosome 6 protein) (Protein AF-6) (Afadin adherens junction formation factor) Homo sapiens (Human) bicellular tight junction assembly [GO:0070830]; cell adhesion [GO:0007155]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell signaling [GO:0007267]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of protein localization to plasma membrane [GO:0061951]; negative regulation of cell migration [GO:0030336]; pore complex assembly [GO:0046931]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of cell-cell adhesion mediated by cadherin [GO:2000049]; positive regulation of gene expression [GO:0010628]; positive regulation of GTPase activity [GO:0043547]; regulation of protein localization [GO:0032880]; signal transduction [GO:0007165] GO:0005654; GO:0005829; GO:0005886; GO:0005911; GO:0005912; GO:0007155; GO:0007165; GO:0007267; GO:0008022; GO:0010628; GO:0016607; GO:0022409; GO:0030054; GO:0030336; GO:0031267; GO:0032880; GO:0043547; GO:0044291; GO:0044331; GO:0045296; GO:0046930; GO:0046931; GO:0050839; GO:0051015; GO:0061951; GO:0070160; GO:0070830; GO:0090557; GO:2000049 33859 XM_029339722.2 0 0 318 0 257 Q7Z7A1 5.12e-79 Centriolin (Centrosomal protein 1) (Centrosomal protein of 110 kDa) (Cep110) Homo sapiens (Human) aorta development [GO:0035904]; cell cycle [GO:0007049]; cell division [GO:0051301]; coronary vasculature development [GO:0060976]; kidney development [GO:0001822]; ventricular septum development [GO:0003281] GO:0001822; GO:0003281; GO:0005813; GO:0005815; GO:0005829; GO:0007049; GO:0016020; GO:0034451; GO:0035904; GO:0048471; GO:0051301; GO:0060976; GO:0090543; GO:0090619; GO:0097431; GO:0120103 33860 XM_029341307.2 742 552 353 491 436 O75582 0 Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 5) (Nuclear mitogen- and stress-activated protein kinase 1) (RSK-like protein kinase) (RSKL) Homo sapiens (Human) axon guidance [GO:0007411]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production [GO:0001818]; negative regulation of DNA-templated transcription [GO:0045892]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-translational protein modification [GO:0043687]; protein phosphorylation [GO:0006468]; regulation of DNA-templated transcription [GO:0006355]; regulation of postsynapse organization [GO:0099175] GO:0000287; GO:0001818; GO:0004674; GO:0004713; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0006355; GO:0006468; GO:0006954; GO:0007411; GO:0018105; GO:0032793; GO:0035175; GO:0035556; GO:0043687; GO:0044022; GO:0044024; GO:0045892; GO:0045944; GO:0051092; GO:0070498; GO:0099175; GO:0106310 33861 XM_029348098.2 66 0 0 0 0 P56705 1.32e-138 Protein Wnt-4 Homo sapiens (Human) adrenal gland development [GO:0030325]; apoptotic signaling pathway [GO:0097190]; branching involved in ureteric bud morphogenesis [GO:0001658]; canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; cellular response to starvation [GO:0009267]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic epithelial tube formation [GO:0001838]; epithelial to mesenchymal transition [GO:0001837]; female gonad development [GO:0008585]; female sex determination [GO:0030237]; fibroblast growth factor receptor signaling pathway [GO:0008543]; hormone metabolic process [GO:0042445]; immature T cell proliferation in thymus [GO:0033080]; kidney development [GO:0001822]; liver development [GO:0001889]; male gonad development [GO:0008584]; mammary gland epithelium development [GO:0061180]; meiotic nuclear division [GO:0140013]; mesenchymal to epithelial transition [GO:0060231]; metanephric mesenchymal cell differentiation [GO:0072162]; metanephric nephron morphogenesis [GO:0072273]; metanephric tubule formation [GO:0072174]; negative regulation of androgen biosynthetic process [GO:2000180]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell migration [GO:0030336]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; negative regulation of gene expression [GO:0010629]; negative regulation of male gonad development [GO:2000019]; negative regulation of steroid biosynthetic process [GO:0010894]; negative regulation of testicular blood vessel morphogenesis [GO:0061369]; negative regulation of testosterone biosynthetic process [GO:2000225]; negative regulation of wound healing [GO:0061045]; neuron differentiation [GO:0030182]; non-canonical Wnt signaling pathway via MAPK cascade [GO:0038030]; oocyte development [GO:0048599]; paramesonephric duct development [GO:0061205]; pericyte cell differentiation [GO:1904238]; positive regulation of aldosterone biosynthetic process [GO:0032349]; positive regulation of bone mineralization [GO:0030501]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of cortisol biosynthetic process [GO:2000066]; positive regulation of dermatome development [GO:0061184]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of GTPase activity [GO:0043547]; positive regulation of meiotic nuclear division [GO:0045836]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of stress fiber assembly [GO:0051496]; regulation of cell-cell adhesion [GO:0022407]; renal vesicle formation [GO:0072033]; renal vesicle induction [GO:0072034]; Sertoli cell differentiation [GO:0060008]; smooth muscle cell differentiation [GO:0051145]; somatotropin secreting cell differentiation [GO:0060126]; tertiary branching involved in mammary gland duct morphogenesis [GO:0060748]; thyroid-stimulating hormone-secreting cell differentiation [GO:0060129] GO:0001658; GO:0001822; GO:0001837; GO:0001838; GO:0001889; GO:0003714; GO:0005109; GO:0005125; GO:0005576; GO:0005615; GO:0005737; GO:0005788; GO:0005796; GO:0005886; GO:0008543; GO:0008584; GO:0008585; GO:0009267; GO:0009986; GO:0010629; GO:0010894; GO:0022407; GO:0030182; GO:0030237; GO:0030325; GO:0030336; GO:0030501; GO:0030666; GO:0031012; GO:0032349; GO:0032967; GO:0033080; GO:0038030; GO:0040037; GO:0042445; GO:0043547; GO:0045165; GO:0045596; GO:0045669; GO:0045836; GO:0045892; GO:0045893; GO:0048018; GO:0048599; GO:0051145; GO:0051496; GO:0051894; GO:0060008; GO:0060070; GO:0060126; GO:0060129; GO:0060231; GO:0060748; GO:0061045; GO:0061180; GO:0061184; GO:0061205; GO:0061369; GO:0070062; GO:0071560; GO:0072033; GO:0072034; GO:0072162; GO:0072174; GO:0072273; GO:0097190; GO:0140013; GO:1904238; GO:2000019; GO:2000066; GO:2000180; GO:2000225; GO:2001234 33862 XM_044308718.1 1 0 0 28 16 NA NA NA NA NA NA 33863 XR_006392922.1 41 2 25 5 151 NA NA NA NA NA NA 33864 XR_003823930.2 91 8 0 107 20 NA NA NA NA NA NA 33865 XM_029338873.2 8755 7227 4253 6951 6343 P42669 2.02e-47 Transcriptional activator protein Pur-alpha (Purine-rich single-stranded DNA-binding protein alpha) Mus musculus (Mouse) cell population proliferation [GO:0008283]; dendritic transport of messenger ribonucleoprotein complex [GO:0098963]; DNA unwinding involved in DNA replication [GO:0006268]; epithelial cell proliferation [GO:0050673]; lymphocyte proliferation [GO:0046651]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; positive regulation of cell population proliferation [GO:0008284]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000900; GO:0000977; GO:0000981; GO:0003677; GO:0003690; GO:0003691; GO:0003697; GO:0003700; GO:0005634; GO:0005737; GO:0006268; GO:0006357; GO:0007399; GO:0008283; GO:0008284; GO:0014069; GO:0030425; GO:0032422; GO:0032839; GO:0043025; GO:0043433; GO:0045892; GO:0046332; GO:0046651; GO:0050673; GO:0098794; GO:0098963; GO:0098978; GO:0140297; GO:0140416 33866 XM_029357179.2 87 83 73 126 223 NA NA NA NA NA NA 33867 XM_029337287.2 190 105 170 186 268 Q7TN88 2.43e-98 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 33868 XM_029337287.2 190 105 170 186 268 Q7TN88 4.06e-85 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 33869 XR_006394581.1 1990 1646 1755 2685 3062 NA NA NA NA NA NA 33870 XM_044316370.1 839 464 1395 1293 2031 NA NA NA NA NA NA 33871 XR_003825395.2 8 20 48 6 3 NA NA NA NA NA NA 33872 XM_029346393.2 520 469 400 714 803 F4KGU4 0 ATP-dependent RNA helicase DEAH12, chloroplastic (EC 3.6.4.13) Arabidopsis thaliana (Mouse-ear cress) NA GO:0003723; GO:0003724; GO:0005524; GO:0009507; GO:0016740; GO:0016887; GO:0046872; GO:0140096 33873 XR_006397256.1 202 114 8 1 70 NA NA NA NA NA NA 33874 XM_029340088.2 0 0 30 0 0 P22300 4.01e-42 Gamma-aminobutyric acid receptor subunit gamma-2 (GABA(A) receptor subunit gamma-2) Bos taurus (Bovine) cellular response to histamine [GO:0071420]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid signaling pathway [GO:0007214]; inhibitory synapse assembly [GO:1904862] GO:0004890; GO:0005230; GO:0005254; GO:0005886; GO:0007214; GO:0030425; GO:0030659; GO:0034707; GO:0045211; GO:0071420; GO:1902476; GO:1902711; GO:1904862 33875 XR_003826695.2 0 23 0 0 0 NA NA NA NA NA NA 33876 XM_044313661.1 0 0 0 35 57 NA NA NA NA NA NA 33877 XM_029351572.2 0 0 0 72 11 NA NA NA NA NA NA 33878 XM_029328487.2 7 0 0 0 2 A0JPI9 1.51e-51 Leucine-rich repeat-containing protein 74A (Leucine-rich repeat-containing protein 74) Rattus norvegicus (Rat) NA NA 33879 XM_044321257.1 1389 815 611 793 924 P46060 4.96e-139 Ran GTPase-activating protein 1 (RanGAP1) Homo sapiens (Human) activation of GTPase activity [GO:0090630]; cellular response to vasopressin [GO:1904117]; negative regulation of protein export from nucleus [GO:0046826]; nuclear export [GO:0051168]; nucleocytoplasmic transport [GO:0006913]; protein sumoylation [GO:0016925]; response to axon injury [GO:0048678]; signal transduction [GO:0007165] GO:0000776; GO:0003723; GO:0005096; GO:0005634; GO:0005635; GO:0005643; GO:0005654; GO:0005737; GO:0005829; GO:0006913; GO:0007165; GO:0016235; GO:0016925; GO:0030425; GO:0031267; GO:0031625; GO:0031965; GO:0043231; GO:0044614; GO:0045296; GO:0046826; GO:0048471; GO:0048678; GO:0051168; GO:0072686; GO:0090630; GO:0106068; GO:1904115; GO:1904117; GO:1990723 33880 XM_044322231.1 436 104 219 216 229 NA NA NA NA NA NA 33881 XM_029333104.2 0 0 5 0 56 P58307 7.32e-28 Orexin/Hypocretin receptor type 1 (Hypocretin receptor type 1) (Orexin receptor type 1) (Ox-1-R) (Ox1-R) (Ox1R) Mus musculus (Mouse) feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0004930; GO:0005886; GO:0007186; GO:0007218; GO:0007631; GO:0016499; GO:0017046; GO:0051480; GO:0070374 33882 XM_029348140.2 2 39 1 34 24 P49338 2.66e-114 Protein Wnt-4 (XWnt-4) Xenopus laevis (African clawed frog) embryonic pattern specification [GO:0009880]; glomus development [GO:0072013]; nephrostome development [GO:0039018]; pronephric nephron tubule development [GO:0039020]; Wnt signaling pathway [GO:0016055] GO:0005102; GO:0005576; GO:0009880; GO:0016055; GO:0039018; GO:0039020; GO:0072013 33883 XM_029356764.2 3311 4400 2515 2901 2195 NA NA NA NA NA NA 33884 XM_044321339.1 23 10 3 18 19 B3EWZ5 3.79e-23 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 33885 XM_044321339.1 23 10 3 18 19 B3EWZ5 9.94e-23 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 33886 XM_044321339.1 23 10 3 18 19 B3EWZ5 3.79e-22 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 33887 XM_044321339.1 23 10 3 18 19 B3EWZ5 4.58e-22 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 33888 XM_044321339.1 23 10 3 18 19 B3EWZ5 7.9e-22 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 33889 XM_044321339.1 23 10 3 18 19 B3EWZ5 1.98e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 33890 XM_044321339.1 23 10 3 18 19 B3EWZ5 2.91e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 33891 XM_044321339.1 23 10 3 18 19 B3EWZ5 9.27e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 33892 XM_029334634.2 0 0 0 64 13 Q66IB8 2.66e-30 UPF0538 protein C2orf76 homolog Danio rerio (Zebrafish) (Brachydanio rerio) NA NA 33893 XR_003824141.2 9 43 52 44 16 NA NA NA NA NA NA 33894 XM_044322692.1 3 2 2 19 39 NA NA NA NA NA NA 33895 XM_029343351.2 135 49 93 127 129 B0WWP2 2.61e-132 Kelch-like protein diablo Culex quinquefasciatus (Southern house mosquito) (Culex pungens) negative regulation of synaptic assembly at neuromuscular junction [GO:0045886]; protein ubiquitination [GO:0016567] GO:0003779; GO:0016567; GO:0045886 33896 XM_029343351.2 135 49 93 127 129 B0WWP2 1.47e-34 Kelch-like protein diablo Culex quinquefasciatus (Southern house mosquito) (Culex pungens) negative regulation of synaptic assembly at neuromuscular junction [GO:0045886]; protein ubiquitination [GO:0016567] GO:0003779; GO:0016567; GO:0045886 33897 XR_006393185.1 16 0 0 17 3 NA NA NA NA NA NA 33898 XM_044325981.1 5 2 1 3 6 NA NA NA NA NA NA 33899 XM_029337801.2 536 329 255 437 576 Q7Z6B0 2.72e-21 Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein) Homo sapiens (Human) Golgi to lysosome transport [GO:0090160]; protein transport [GO:0015031] GO:0005654; GO:0005794; GO:0005802; GO:0005829; GO:0015031; GO:0016020; GO:0090160 33900 XM_029344303.2 65 86 94 62 177 O75762 2.87e-121 Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation-sensitive protein p120) (p120) (Wasabi receptor) Homo sapiens (Human) calcium ion transmembrane transport [GO:0070588]; cell surface receptor signaling pathway [GO:0007166]; cellular calcium ion homeostasis [GO:0006874]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to organic substance [GO:0071310]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; ion transport [GO:0006811]; protein homotetramerization [GO:0051289]; response to cold [GO:0009409]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; sensory perception of pain [GO:0019233]; thermoception [GO:0050955] GO:0005262; GO:0005886; GO:0006811; GO:0006874; GO:0007166; GO:0009409; GO:0009410; GO:0010033; GO:0014070; GO:0015267; GO:0015278; GO:0019233; GO:0032421; GO:0042802; GO:0048265; GO:0050955; GO:0050966; GO:0050968; GO:0051289; GO:0070301; GO:0070588; GO:0071310; GO:0097604 33901 XM_029354863.2 568 726 43 1097 437 O88974 7.88e-76 Histone-lysine N-methyltransferase SETDB1 (EC 2.1.1.366) (ERG-associated protein with SET domain) (ESET) (SET domain bifurcated 1) Mus musculus (Mouse) bone development [GO:0060348]; heterochromatin organization [GO:0070828]; histone H3-K9 methylation [GO:0051567]; inner cell mass cell proliferation [GO:0001833]; negative regulation of gene expression [GO:0010629]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA methylation-dependent heterochromatin formation [GO:0090309]; Ras protein signal transduction [GO:0007265] GO:0000122; GO:0001833; GO:0003677; GO:0003682; GO:0005634; GO:0005654; GO:0005694; GO:0005737; GO:0007265; GO:0008270; GO:0010629; GO:0018024; GO:0043231; GO:0045869; GO:0046974; GO:0051567; GO:0060348; GO:0070828; GO:0090309; GO:0140947; GO:0140948; GO:1990841 33902 XM_029354863.2 568 726 43 1097 437 O88974 1.91e-44 Histone-lysine N-methyltransferase SETDB1 (EC 2.1.1.366) (ERG-associated protein with SET domain) (ESET) (SET domain bifurcated 1) Mus musculus (Mouse) bone development [GO:0060348]; heterochromatin organization [GO:0070828]; histone H3-K9 methylation [GO:0051567]; inner cell mass cell proliferation [GO:0001833]; negative regulation of gene expression [GO:0010629]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA methylation-dependent heterochromatin formation [GO:0090309]; Ras protein signal transduction [GO:0007265] GO:0000122; GO:0001833; GO:0003677; GO:0003682; GO:0005634; GO:0005654; GO:0005694; GO:0005737; GO:0007265; GO:0008270; GO:0010629; GO:0018024; GO:0043231; GO:0045869; GO:0046974; GO:0051567; GO:0060348; GO:0070828; GO:0090309; GO:0140947; GO:0140948; GO:1990841 33903 XM_029354863.2 568 726 43 1097 437 O88974 4.25e-39 Histone-lysine N-methyltransferase SETDB1 (EC 2.1.1.366) (ERG-associated protein with SET domain) (ESET) (SET domain bifurcated 1) Mus musculus (Mouse) bone development [GO:0060348]; heterochromatin organization [GO:0070828]; histone H3-K9 methylation [GO:0051567]; inner cell mass cell proliferation [GO:0001833]; negative regulation of gene expression [GO:0010629]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA methylation-dependent heterochromatin formation [GO:0090309]; Ras protein signal transduction [GO:0007265] GO:0000122; GO:0001833; GO:0003677; GO:0003682; GO:0005634; GO:0005654; GO:0005694; GO:0005737; GO:0007265; GO:0008270; GO:0010629; GO:0018024; GO:0043231; GO:0045869; GO:0046974; GO:0051567; GO:0060348; GO:0070828; GO:0090309; GO:0140947; GO:0140948; GO:1990841 33904 XR_006398104.1 203 84 113 168 275 NA NA NA NA NA NA 33905 XM_029324073.2 445 344 197 235 389 Q5RCI5 4.24e-24 Citrate synthase-lysine N-methyltransferase CSKMT, mitochondrial (CS-KMT) (EC 2.1.1.-) (Methyltransferase-like protein 12, mitochondrial) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) peptidyl-lysine dimethylation [GO:0018027]; peptidyl-lysine monomethylation [GO:0018026]; peptidyl-lysine trimethylation [GO:0018023]; protein methylation [GO:0006479] GO:0005739; GO:0006479; GO:0016278; GO:0016279; GO:0018023; GO:0018026; GO:0018027 33906 XM_029343959.2 959 503 437 863 614 Q8INF0 0 Soluble guanylate cyclase 88E (EC 4.6.1.2) Drosophila melanogaster (Fruit fly) cGMP-mediated signaling [GO:0019934]; nitric oxide-cGMP-mediated signaling pathway [GO:0038060]; response to hypoxia [GO:0001666]; response to oxygen levels [GO:0070482]; response to reactive oxygen species [GO:0000302] GO:0000302; GO:0001666; GO:0003924; GO:0004383; GO:0005525; GO:0008074; GO:0019825; GO:0019826; GO:0019899; GO:0019934; GO:0020037; GO:0038060; GO:0042803; GO:0046872; GO:0046982; GO:0070025; GO:0070026; GO:0070482 33907 XM_029340236.2 391 286 395 469 269 Q9NPD3 4.7e-106 Exosome complex component RRP41 (Exosome component 4) (Ribosomal RNA-processing protein 41) (p12A) Homo sapiens (Human) defense response to virus [GO:0051607]; DNA deamination [GO:0045006]; histone mRNA catabolic process [GO:0071044]; maturation of 5.8S rRNA [GO:0000460]; nuclear mRNA surveillance [GO:0071028]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; positive regulation of cell growth [GO:0030307]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; U4 snRNA 3'-end processing [GO:0034475] GO:0000175; GO:0000176; GO:0000177; GO:0000178; GO:0000460; GO:0000791; GO:0000956; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0006364; GO:0006396; GO:0006401; GO:0016075; GO:0030307; GO:0034427; GO:0034475; GO:0035925; GO:0043231; GO:0045006; GO:0051607; GO:0071028; GO:0071044; GO:0071051; GO:0101019 33908 XM_029330603.2 99 78 72 134 160 NA NA NA NA NA NA 33909 XM_029348790.2 1162 953 587 951 630 Q8BIK4 0 Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin-1) (Zizimin-1) Mus musculus (Mouse) positive regulation of GTPase activity [GO:0043547]; small GTPase mediated signal transduction [GO:0007264] GO:0005085; GO:0007264; GO:0012505; GO:0016020; GO:0031267; GO:0043547 33910 XM_029352964.2 164 118 120 90 157 Q8BFR2 5.73e-56 Follistatin-related protein 5 (Follistatin-like protein 5) (m-D/Bsp120I 1-2) Mus musculus (Mouse) cell differentiation [GO:0030154] GO:0005509; GO:0005576; GO:0030154 33911 XM_029352964.2 164 118 120 90 157 Q8BFR2 4.3e-22 Follistatin-related protein 5 (Follistatin-like protein 5) (m-D/Bsp120I 1-2) Mus musculus (Mouse) cell differentiation [GO:0030154] GO:0005509; GO:0005576; GO:0030154 33912 XM_044317517.1 287 106 4 0 37 NA NA NA NA NA NA 33913 XM_044322377.1 188 332 128 260 323 Q9XTR8 1.19e-24 Lipase ZK262.3 (EC 3.1.1.-) Caenorhabditis elegans lipid catabolic process [GO:0016042] GO:0005576; GO:0016042; GO:0016787 33914 XM_044315834.1 3 2 4 6 126 NA NA NA NA NA NA 33915 XM_044315858.1 0 0 10 34 73 Q28I85 0 POC1 centriolar protein homolog A (Pat-interacting protein 2) (Pix2) (xPix2) (WD repeat-containing protein 51A) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737; GO:0005856 33916 XM_029340406.2 508 2142 426 563 203 NA NA NA NA NA NA 33917 XM_044307347.1 2 5 18 7 8 P79385 2.78e-25 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (SED1) (Sperm surface protein SP47) (PP47) Sus scrofa (Pig) angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; single fertilization [GO:0007338] GO:0001525; GO:0002080; GO:0005576; GO:0007155; GO:0007338 33918 XM_029350759.2 0 349 426 0 301 P51029 1.69e-73 Protein Wnt-8b Danio rerio (Zebrafish) (Brachydanio rerio) canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; commissural neuron axon guidance [GO:0071679]; embryonic pattern specification [GO:0009880]; eye development [GO:0001654]; eye field cell fate commitment involved in camera-type eye formation [GO:0060898]; forebrain development [GO:0030900]; forebrain neuron differentiation [GO:0021879]; hypothalamus development [GO:0021854]; negative regulation of anterior neural cell fate commitment of the neural plate by Wnt signaling pathway [GO:0022002]; neuron differentiation [GO:0030182]; otic placode formation [GO:0043049]; sensory epithelium regeneration [GO:0070654] GO:0001654; GO:0005109; GO:0005125; GO:0005615; GO:0009880; GO:0021854; GO:0021879; GO:0022002; GO:0030182; GO:0030900; GO:0043049; GO:0045165; GO:0060070; GO:0060898; GO:0070654; GO:0071679 33919 XM_044319148.1 64 38 52 41 12 NA NA NA NA NA NA 33920 XM_029327819.2 1574 1921 481 996 1047 NA NA NA NA NA NA 33921 XM_029327083.2 5312 4273 3409 7068 5671 Q7ZVZ7 1.56e-162 Alpha/beta hydrolase domain-containing protein 17C (Abhydrolase domain-containing protein 17C) (EC 3.1.2.22) Danio rerio (Zebrafish) (Brachydanio rerio) protein depalmitoylation [GO:0002084]; regulation of postsynapse organization [GO:0099175] GO:0002084; GO:0005886; GO:0008474; GO:0010008; GO:0043197; GO:0055038; GO:0098839; GO:0099175 33922 XM_029329769.2 21 0 0 6 39 NA NA NA NA NA NA 33923 XM_029356215.2 29 36 39 48 26 Q04892 2.89e-32 Transcription factor SOX-14 Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; entrainment of circadian clock [GO:0009649]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355]; regulation of neuron migration [GO:2001222]; visual perception [GO:0007601] GO:0000122; GO:0000978; GO:0000981; GO:0003682; GO:0005634; GO:0005667; GO:0006355; GO:0007601; GO:0009649; GO:0009653; GO:0030154; GO:0043565; GO:0045892; GO:1990837; GO:2001222 33924 XM_029327148.2 0 25 84 40 110 P43140 3.44e-29 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) Rattus norvegicus (Rat) activation of phospholipase C activity [GO:0007202]; adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; adrenergic receptor signaling pathway [GO:0071875]; adult heart development [GO:0007512]; aging [GO:0007568]; calcium ion transport into cytosol [GO:0060402]; cell growth involved in cardiac muscle cell development [GO:0061049]; cell-cell signaling [GO:0007267]; MAPK cascade [GO:0000165]; micturition [GO:0060073]; multicellular organism aging [GO:0010259]; negative regulation of autophagy [GO:0010507]; negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure [GO:0001985]; negative regulation of Rho protein signal transduction [GO:0035024]; neuron-glial cell signaling [GO:0150099]; norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001994]; organ growth [GO:0035265]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; pilomotor reflex [GO:0097195]; positive regulation of action potential [GO:0045760]; positive regulation of cardiac muscle contraction [GO:0060452]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of heart rate [GO:0010460]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; positive regulation of systemic arterial blood pressure [GO:0003084]; positive regulation of the force of heart contraction by epinephrine-norepinephrine [GO:0001997]; positive regulation of vasoconstriction [GO:0045907]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of blood pressure [GO:0008217]; response to hormone [GO:0009725]; response to xenobiotic stimulus [GO:0009410] GO:0000165; GO:0001985; GO:0001994; GO:0001996; GO:0001997; GO:0003084; GO:0004930; GO:0004937; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0005901; GO:0007200; GO:0007202; GO:0007204; GO:0007267; GO:0007512; GO:0007568; GO:0008217; GO:0009410; GO:0009725; GO:0010259; GO:0010460; GO:0010507; GO:0010613; GO:0016020; GO:0030018; GO:0030315; GO:0031965; GO:0032230; GO:0035024; GO:0035265; GO:0042734; GO:0043410; GO:0045211; GO:0045760; GO:0045907; GO:0045987; GO:0046982; GO:0060073; GO:0060402; GO:0060452; GO:0061049; GO:0070374; GO:0071875; GO:0071880; GO:0090037; GO:0097195; GO:0098691; GO:0098978; GO:0098982; GO:0099171; GO:0150099; GO:1903997 33925 XM_044325534.1 0 100 0 0 0 B1AS29 1.09e-82 Glutamate receptor ionotropic, kainate 3 (GluK3) (Glutamate receptor 7) (GluR-7) (GluR7) Mus musculus (Mouse) G protein-coupled glutamate receptor signaling pathway [GO:0007216]; glutamate receptor signaling pathway [GO:0007215]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; regulation of membrane potential [GO:0042391]; synaptic transmission, glutamatergic [GO:0035249] GO:0001640; GO:0004970; GO:0005886; GO:0007215; GO:0007216; GO:0008066; GO:0015276; GO:0015277; GO:0030424; GO:0030425; GO:0032839; GO:0032983; GO:0035249; GO:0038023; GO:0042391; GO:0042734; GO:0043195; GO:0043204; GO:0045211; GO:0050804; GO:0051967; GO:0098978; GO:0099507; GO:1904315 33926 XM_029329871.2 295 592 155 788 246 P20072 1.33e-70 Annexin A7 (Annexin VII) (Annexin-7) (Synexin) Bos taurus (Bovine) NA GO:0005509; GO:0005544; GO:0005634; GO:0005737; GO:0042584 33927 XM_029336248.2 2892 2763 2760 2178 2192 Q86SQ9 3.44e-119 Dehydrodolichyl diphosphate synthase complex subunit DHDDS (EC 2.5.1.87) (Cis-isoprenyltransferase) (CIT) (Cis-IPTase) (Cis-prenyltransferase subunit hCIT) (Epididymis tissue protein Li 189m) Homo sapiens (Human) dolichyl diphosphate biosynthetic process [GO:0006489]; polyprenol biosynthetic process [GO:0016094] GO:0005783; GO:0005789; GO:0006489; GO:0016094; GO:0045547; GO:0046872; GO:1904423 33928 XM_044307372.1 167 246 168 112 96 Q8TB61 3.4e-112 Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (PAPS transporter 1) (Putative MAPK-activating protein PM15) (Putative NF-kappa-B-activating protein 48) (Solute carrier family 35 member B2) Homo sapiens (Human) 3'-phosphoadenosine 5'-phosphosulfate transport [GO:0046963]; 5'-adenylyl sulfate transmembrane transport [GO:1902558]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123] GO:0000139; GO:0005789; GO:0005794; GO:0016020; GO:0022857; GO:0043123; GO:0046963; GO:0046964; GO:1902558 33929 XM_044307228.1 53 18 45 89 87 NA NA NA NA NA NA 33930 XR_006392474.1 394 665 290 226 181 NA NA NA NA NA NA 33931 XM_029324150.2 2573 2278 1080 2378 2126 Q9W6T7 1.23e-119 Presenilin-1 (PS-1) (Zf-PS1) (EC 3.4.23.-) Danio rerio (Zebrafish) (Brachydanio rerio) amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta formation [GO:0034205]; amyloid-beta metabolic process [GO:0050435]; brain development [GO:0007420]; calcium ion transport [GO:0006816]; canonical Wnt signaling pathway [GO:0060070]; lymphangiogenesis [GO:0001946]; melanocyte differentiation [GO:0030318]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of apoptotic process [GO:0043066]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; optomotor response [GO:0071632]; positive regulation of catalytic activity [GO:0043085]; protein processing [GO:0016485]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of endopeptidase activity [GO:0052548]; response to hypoxia [GO:0001666]; smooth endoplasmic reticulum calcium ion homeostasis [GO:0051563]; somite development [GO:0061053]; swimming behavior [GO:0036269] GO:0000139; GO:0001666; GO:0001946; GO:0004175; GO:0005634; GO:0005739; GO:0005743; GO:0005765; GO:0005783; GO:0005789; GO:0005790; GO:0005794; GO:0005886; GO:0005938; GO:0006509; GO:0006816; GO:0007219; GO:0007220; GO:0007420; GO:0008013; GO:0009986; GO:0016020; GO:0016324; GO:0016485; GO:0030018; GO:0030318; GO:0030426; GO:0031594; GO:0034205; GO:0035253; GO:0036269; GO:0042500; GO:0042987; GO:0043025; GO:0043066; GO:0043085; GO:0043198; GO:0045121; GO:0045296; GO:0048471; GO:0050435; GO:0051563; GO:0052548; GO:0060070; GO:0060828; GO:0061053; GO:0070765; GO:0071632 33932 XM_029328792.2 0 21 0 0 0 NA NA NA NA NA NA 33933 XM_029340637.2 4930 5353 4342 4821 3450 NA NA NA NA NA NA 33934 XM_029323832.2 0 5 3 0 8 NA NA NA NA NA NA 33935 XM_044320393.1 4517 4415 1825 11469 5622 NA NA NA NA NA NA 33936 XM_029328728.2 10 24 76 0 110 NA NA NA NA NA NA 33937 XR_006391678.1 733 716 673 990 1345 NA NA NA NA NA NA 33938 XM_044327376.1 258 91 111 369 437 NA NA NA NA NA NA 33939 XM_044325624.1 101 79 71 143 243 Q9HAR2 1.44e-58 Adhesion G protein-coupled receptor L3 (Calcium-independent alpha-latrotoxin receptor 3) (CIRL-3) (Latrophilin-3) (Lectomedin-3) Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; brain development [GO:0007420]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; G protein-coupled receptor signaling pathway [GO:0007186]; neuron migration [GO:0001764]; synapse assembly [GO:0007416] GO:0001764; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007166; GO:0007186; GO:0007189; GO:0007416; GO:0007420; GO:0016020; GO:0030246; GO:0030424; GO:0098742; GO:0098978 33940 XM_029336751.2 493 0 407 609 87 P82343 2.11e-147 N-acylglucosamine 2-epimerase (AGE) (EC 5.1.3.8) (GlcNAc 2-epimerase) (N-acetyl-D-glucosamine 2-epimerase) (Renin-binding protein) (RnBP) Mus musculus (Mouse) carbohydrate metabolic process [GO:0005975]; N-acetylglucosamine metabolic process [GO:0006044]; N-acetylmannosamine metabolic process [GO:0006051]; N-acetylneuraminate catabolic process [GO:0019262]; negative regulation of catalytic activity [GO:0043086]; negative regulation of endopeptidase activity [GO:0010951] GO:0004857; GO:0005524; GO:0005975; GO:0006044; GO:0006051; GO:0010951; GO:0017076; GO:0019262; GO:0030414; GO:0042802; GO:0043086; GO:0050121 33941 XM_044326013.1 2 76 3 14 28 NA NA NA NA NA NA 33942 XM_029357245.2 84 142 77 130 51 NA NA NA NA NA NA 33943 XM_044326318.1 122 70 50 146 143 NA NA NA NA NA NA 33944 XM_029357861.2 185 123 82 43 117 Q9WTK3 1.29e-94 Glycosylphosphatidylinositol anchor attachment 1 protein (GPI anchor attachment protein 1) (GAA1 protein homolog) (mGAA1) Mus musculus (Mouse) attachment of GPI anchor to protein [GO:0016255]; GPI anchor biosynthetic process [GO:0006506]; protein-containing complex assembly [GO:0065003] GO:0003923; GO:0005739; GO:0005783; GO:0005813; GO:0005829; GO:0005886; GO:0006506; GO:0016020; GO:0016255; GO:0034235; GO:0042765; GO:0065003 33945 XM_029334189.2 50 0 0 0 0 P25931 3.68e-34 RYamide receptor (Neuropeptide Y-like receptor) (NPY-R) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218] GO:0001653; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0016020 33946 XM_044324166.1 3731 4385 3666 4070 2769 Q9D0B5 2.73e-24 Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 3 (Rhodanese domain-containing protein 3) Mus musculus (Mouse) NA GO:0004792 33947 XM_044324166.1 3731 4385 3666 4070 2769 Q9D0B5 4.43e-23 Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 3 (Rhodanese domain-containing protein 3) Mus musculus (Mouse) NA GO:0004792 33948 XM_044327149.1 1006 1079 665 2856 1088 B8VIW9 0 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 33949 XM_044318313.1 77 69 94 143 140 NA NA NA NA NA NA 33950 XR_006396617.1 1826 2144 1591 354 1563 NA NA NA NA NA NA 33951 XM_044309099.1 0 72 0 140 0 NA NA NA NA NA NA 33952 XM_029342774.2 0 0 0 72 0 Q64077 5.25e-25 Substance-K receptor (SKR) (NK-2 receptor) (NK-2R) (Neurokinin A receptor) (Tachykinin receptor 2) Cavia porcellus (Guinea pig) positive regulation of flagellated sperm motility [GO:1902093]; regulation of uterine smooth muscle contraction [GO:0070472] GO:0004995; GO:0005886; GO:0061827; GO:0070472; GO:0097225; GO:1902093 33953 XR_006396699.1 21 8 7 1 46 NA NA NA NA NA NA 33954 XM_044319215.1 0 0 82 35 129 NA NA NA NA NA NA 33955 XM_029337929.2 2684 4226 1072 3938 2117 NA NA NA NA NA NA 33956 XM_044318210.1 13 5 0 6 21 NA NA NA NA NA NA 33957 XM_029330508.2 49 48 21 37 55 NA NA NA NA NA NA 33958 XM_029356606.2 8 0 0 0 8 NA NA NA NA NA NA 33959 XM_029339491.2 1455 1068 762 1606 1622 Q9UPS8 3.36e-33 Ankyrin repeat domain-containing protein 26 Homo sapiens (Human) negative regulation of fat cell differentiation [GO:0045599] GO:0005813; GO:0045599 33960 XM_029339491.2 1455 1068 762 1606 1622 Q9UPS8 4.15e-25 Ankyrin repeat domain-containing protein 26 Homo sapiens (Human) negative regulation of fat cell differentiation [GO:0045599] GO:0005813; GO:0045599 33961 XM_029344973.2 2609 1910 1482 2190 1931 P70445 1.82e-31 Eukaryotic translation initiation factor 4E-binding protein 2 (4E-BP2) (eIF4E-binding protein 2) (Phosphorylated heat- and acid-stable protein regulated by insulin 2) (PHAS-II) Mus musculus (Mouse) insulin receptor signaling pathway [GO:0008286]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of translational initiation [GO:0045947]; regulation of synaptic plasticity [GO:0048167]; regulation of translational initiation [GO:0006446]; social behavior [GO:0035176]; TOR signaling [GO:0031929] GO:0005737; GO:0006446; GO:0007613; GO:0008190; GO:0008286; GO:0030371; GO:0031929; GO:0035176; GO:0045947; GO:0048167; GO:0050804; GO:0098794 33962 XM_029348031.2 1112 1094 622 778 1049 NA NA NA NA NA NA 33963 XM_029339479.2 9929 10628 4783 11370 7898 Q91827 4.28e-23 Apoptosis regulator R1 (XR1) Xenopus laevis (African clawed frog) apoptotic process [GO:0006915]; regulation of apoptotic process [GO:0042981] GO:0006915; GO:0016020; GO:0042981 33964 XR_006397262.1 0 18 0 0 5 NA NA NA NA NA NA 33965 XM_044323764.1 17 4 24 3 21 NA NA NA NA NA NA 33966 XR_006394997.1 307 634 179 261 227 NA NA NA NA NA NA 33967 XM_044324087.1 173 12 12 6 165 NA NA NA NA NA NA 33968 XM_044327570.1 1 156 0 0 0 Q9H267 1.95e-174 Vacuolar protein sorting-associated protein 33B (hVPS33B) Homo sapiens (Human) collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; endosome organization [GO:0007032]; intracellular protein transport [GO:0006886]; intracellular transport [GO:0046907]; lysosome localization [GO:0032418]; megakaryocyte development [GO:0035855]; melanosome localization [GO:0032400]; membrane fusion [GO:0061025]; peptidyl-lysine hydroxylation [GO:0017185]; phagosome-lysosome fusion [GO:0090385]; platelet alpha granule organization [GO:0070889]; protein transport [GO:0015031]; regulation of platelet aggregation [GO:0090330]; vesicle-mediated transport [GO:0016192] GO:0005737; GO:0005764; GO:0005765; GO:0005768; GO:0005770; GO:0005773; GO:0005794; GO:0005829; GO:0006886; GO:0007032; GO:0010008; GO:0015031; GO:0016192; GO:0017185; GO:0030136; GO:0030199; GO:0030897; GO:0031091; GO:0031901; GO:0031902; GO:0032400; GO:0032418; GO:0032963; GO:0033263; GO:0035855; GO:0044877; GO:0046907; GO:0048471; GO:0055037; GO:0061025; GO:0070889; GO:0090330; GO:0090385; GO:0099023 33969 XM_044319147.1 1233 491 460 1378 842 NA NA NA NA NA NA 33970 XM_044315168.1 90 0 94 330 0 C5FYZ3 2.02e-66 Probable dipeptidyl-aminopeptidase B (DPAP B) (EC 3.4.14.5) Arthroderma otae (strain ATCC MYA-4605 / CBS 113480) (Microsporum canis) proteolysis [GO:0006508] GO:0004177; GO:0005774; GO:0006508; GO:0008236; GO:0008239 33971 XM_044312868.1 246 186 134 286 328 Q96JM7 1.64e-112 Lethal(3)malignant brain tumor-like protein 3 (H-l(3)mbt-like protein 3) (L(3)mbt-like protein 3) (L3mbt-like 3) (MBT-1) Homo sapiens (Human) chromatin organization [GO:0006325]; erythrocyte maturation [GO:0043249]; granulocyte differentiation [GO:0030851]; macrophage differentiation [GO:0030225]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; regulation of DNA methylation-dependent heterochromatin formation [GO:0090308] GO:0003682; GO:0005634; GO:0005654; GO:0005730; GO:0006325; GO:0008270; GO:0030225; GO:0030851; GO:0042393; GO:0042802; GO:0043249; GO:0045892; GO:0090308; GO:0140034; GO:2000060 33972 XM_029353085.2 3138 2459 2077 2044 2153 Q7ZUX6 5.03e-136 Deoxyhypusine hydroxylase (DOHH) (EC 1.14.99.29) (Deoxyhypusine dioxygenase) (Deoxyhypusine monooxygenase) Danio rerio (Zebrafish) (Brachydanio rerio) peptidyl-lysine modification to peptidyl-hypusine [GO:0008612] GO:0005506; GO:0008612; GO:0016491; GO:0019135 33973 XM_029326107.2 930 310 165 548 8 NA NA NA NA NA NA 33974 XM_029337003.2 88 141 134 159 206 NA NA NA NA NA NA 33975 XM_044319848.1 70 9 8 113 57 Q7TNH6 2.97e-46 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 33976 XM_044319848.1 70 9 8 113 57 Q7TNH6 1.43e-44 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 33977 XM_044319848.1 70 9 8 113 57 Q7TNH6 1.43e-39 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 33978 XM_029329238.2 24 16 42 28 120 NA NA NA NA NA NA 33979 XM_044328801.1 250 54 25 98 30 Q7RTR2 1.73e-40 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 33980 XM_044328801.1 250 54 25 98 30 Q7RTR2 3.85e-27 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 33981 XM_044310296.1 17 7 5 2 8 Q80XJ3 1.54e-48 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 33982 XM_044310296.1 17 7 5 2 8 Q80XJ3 3.48e-47 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 33983 XM_044310296.1 17 7 5 2 8 Q80XJ3 8.77e-46 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 33984 XM_044310296.1 17 7 5 2 8 Q80XJ3 7.38e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 33985 XM_044310296.1 17 7 5 2 8 Q80XJ3 4.26e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 33986 XM_044310296.1 17 7 5 2 8 Q80XJ3 4.47e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 33987 XM_044310296.1 17 7 5 2 8 Q80XJ3 1.63e-37 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 33988 XM_044310296.1 17 7 5 2 8 Q80XJ3 6.82e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 33989 XM_044310296.1 17 7 5 2 8 Q80XJ3 1.13e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 33990 XM_044310296.1 17 7 5 2 8 Q80XJ3 7.34e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 33991 XM_044312816.1 741 497 409 384 485 NA NA NA NA NA NA 33992 XR_006395670.1 67 0 6 33 37 NA NA NA NA NA NA 33993 XM_044313648.1 105 28 51 47 12 C3VPR6 2.81e-24 Protein NLRC5 Mus musculus (Mouse) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of type II interferon-mediated signaling pathway [GO:0060335]; regulation of kinase activity [GO:0043549]; response to bacterium [GO:0009617] GO:0000978; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0009617; GO:0032088; GO:0035556; GO:0043549; GO:0045087; GO:0045345; GO:0045944; GO:0051607; GO:0060335; GO:0060339; GO:0060340 33994 XM_044323536.1 0 0 0 0 17 NA NA NA NA NA NA 33995 XR_006394425.1 0 2 0 28 0 NA NA NA NA NA NA 33996 XM_029331088.2 0 50 59 297 0 Q9BXB4 0 Oxysterol-binding protein-related protein 11 (ORP-11) (OSBP-related protein 11) Homo sapiens (Human) fat cell differentiation [GO:0045444]; positive regulation of sequestering of triglyceride [GO:0010890] GO:0005654; GO:0005794; GO:0005829; GO:0010890; GO:0015248; GO:0016020; GO:0031902; GO:0032934; GO:0043231; GO:0045444 33997 XM_029356432.2 318 367 194 399 290 Q96DE0 4.76e-32 U8 snoRNA-decapping enzyme (EC 3.6.1.62) (IDP phosphatase) (IDPase) (EC 3.6.1.64) (Inosine diphosphate phosphatase) (Nucleoside diphosphate-linked moiety X motif 16) (Nudix motif 16) (Nudix hydrolase 16) (U8 snoRNA-binding protein H29K) (m7GpppN-mRNA hydrolase) Homo sapiens (Human) dITP catabolic process [GO:0035863]; mRNA catabolic process [GO:0006402]; NAD-cap decapping [GO:0110155]; negative regulation of rRNA processing [GO:2000233]; positive regulation of cell cycle process [GO:0090068]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; sno(s)RNA catabolic process [GO:0016077] GO:0000166; GO:0000287; GO:0003729; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0006402; GO:0008235; GO:0016077; GO:0030145; GO:0030515; GO:0031404; GO:0035863; GO:0035870; GO:0042802; GO:0042803; GO:0050072; GO:0050897; GO:0090068; GO:0090502; GO:0097383; GO:0110153; GO:0110155; GO:0140933; GO:1990003; GO:1990174; GO:2000233 33998 XM_044307783.1 84 41 118 42 27 Q29081 7.16e-69 Phosphomevalonate kinase (PMKase) (EC 2.7.4.2) Sus scrofa (Pig) cholesterol biosynthetic process [GO:0006695]; isopentenyl diphosphate biosynthetic process, mevalonate pathway [GO:0019287]; phosphorylation [GO:0016310]; response to cholesterol [GO:0070723] GO:0004631; GO:0005524; GO:0005829; GO:0006695; GO:0016310; GO:0019287; GO:0070723 33999 XM_029334064.2 2363 1256 1210 2530 2586 Q6ZQ03 6.05e-32 Formin-binding protein 4 (Formin-binding protein 30) Mus musculus (Mouse) NA GO:0016607 34000 XM_044313865.1 2029 375 241 179 20 NA NA NA NA NA NA 34001 XM_044316642.1 246 276 124 279 221 P30937 2.05e-21 Somatostatin receptor type 4 (SS-4-R) (SS4-R) (SS4R) Rattus norvegicus (Rat) cell migration [GO:0016477]; cellular response to glucocorticoid stimulus [GO:0071385]; forebrain development [GO:0030900]; negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0106072]; neuropeptide signaling pathway [GO:0007218]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0004930; GO:0004994; GO:0005737; GO:0005886; GO:0007218; GO:0016477; GO:0030900; GO:0042277; GO:0042923; GO:0043005; GO:0070374; GO:0071385; GO:0090238; GO:0106072 34002 XR_006393130.1 897 2674 2575 1797 1448 NA NA NA NA NA NA 34003 XM_029345396.2 806 321 349 220 240 Q8CAI1 2.5e-24 Coiled-coil domain-containing protein 142 Mus musculus (Mouse) NA NA 34004 XM_029353717.2 371 186 220 142 1566 NA NA NA NA NA NA 34005 XM_029356724.2 1282 1486 764 1166 1004 NA NA NA NA NA NA 34006 XM_044311738.1 2 3 9 3 9 Q96AY4 1.31e-53 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34007 XM_044311738.1 2 3 9 3 9 Q96AY4 7.18e-53 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34008 XM_044311738.1 2 3 9 3 9 Q96AY4 9.36e-51 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34009 XM_044311738.1 2 3 9 3 9 Q96AY4 1.95e-48 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34010 XM_044311738.1 2 3 9 3 9 Q96AY4 2.51e-48 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34011 XM_044311738.1 2 3 9 3 9 Q96AY4 4.24e-47 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34012 XM_044311738.1 2 3 9 3 9 Q96AY4 1.33e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34013 XM_044311738.1 2 3 9 3 9 Q96AY4 1.12e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34014 XM_044311738.1 2 3 9 3 9 Q96AY4 3.92e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34015 XM_044311738.1 2 3 9 3 9 Q96AY4 5.83e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34016 XM_044311738.1 2 3 9 3 9 Q96AY4 3.82e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34017 XM_044311738.1 2 3 9 3 9 Q96AY4 2.22e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34018 XM_044311738.1 2 3 9 3 9 Q96AY4 6.93e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34019 XM_044311738.1 2 3 9 3 9 Q96AY4 7.89e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34020 XM_044311738.1 2 3 9 3 9 Q96AY4 7.14e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34021 XM_044311738.1 2 3 9 3 9 Q96AY4 1.97e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34022 XM_029323511.2 0 5 28 4 4 NA NA NA NA NA NA 34023 XR_006391786.1 9 0 0 6 7 NA NA NA NA NA NA 34024 XM_044307607.1 6 41 6 65 66 NA NA NA NA NA NA 34025 XM_044327081.1 38 19 10 17 11 NA NA NA NA NA NA 34026 XM_044317292.1 2110 1089 965 1720 1557 Q6PCJ1 0 Dynactin subunit 1 Xenopus laevis (African clawed frog) cell division [GO:0051301]; cytoplasmic microtubule organization [GO:0031122]; establishment of mitotic spindle orientation [GO:0000132]; positive regulation of intracellular protein transport [GO:0090316]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000776; GO:0005813; GO:0005814; GO:0005819; GO:0005874; GO:0005938; GO:0008017; GO:0030286; GO:0031122; GO:0035371; GO:0051301; GO:0060236; GO:0090316; GO:0099738 34027 XM_044317292.1 2110 1089 965 1720 1557 Q6PCJ1 7.97e-30 Dynactin subunit 1 Xenopus laevis (African clawed frog) cell division [GO:0051301]; cytoplasmic microtubule organization [GO:0031122]; establishment of mitotic spindle orientation [GO:0000132]; positive regulation of intracellular protein transport [GO:0090316]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000776; GO:0005813; GO:0005814; GO:0005819; GO:0005874; GO:0005938; GO:0008017; GO:0030286; GO:0031122; GO:0035371; GO:0051301; GO:0060236; GO:0090316; GO:0099738 34028 XM_029356110.2 77 5 15 24 27 O88491 0 Histone-lysine N-methyltransferase, H3 lysine-36 specific (EC 2.1.1.357) (H3-K36-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) Mus musculus (Mouse) chromatin organization [GO:0006325]; gastrulation with mouth forming second [GO:0001702]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA-templated transcription [GO:0006355]; regulation of peptidyl-serine phosphorylation [GO:0033135]; regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903025] GO:0000122; GO:0000785; GO:0000978; GO:0001702; GO:0003682; GO:0003712; GO:0003714; GO:0005634; GO:0006325; GO:0006355; GO:0008270; GO:0030331; GO:0033135; GO:0035097; GO:0042054; GO:0042799; GO:0042974; GO:0045893; GO:0046965; GO:0046966; GO:0046975; GO:0050681; GO:0140954; GO:1903025 34029 XM_029341375.2 60 45 24 55 53 Q8BP74 7.9e-33 L-seryl-tRNA(Sec) kinase (EC 2.7.1.164) (O-phosphoseryl-tRNA(Sec) kinase) Mus musculus (Mouse) phosphorylation [GO:0016310]; selenocysteine incorporation [GO:0001514]; selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056] GO:0000049; GO:0001514; GO:0005524; GO:0005739; GO:0005829; GO:0016301; GO:0016310; GO:0043915; GO:0097056 34030 XM_029344487.2 521 193 228 526 265 Q8WU67 2.04e-120 Phospholipase ABHD3 (EC 3.1.1.32) (EC 3.1.1.4) (Abhydrolase domain-containing protein 3) Homo sapiens (Human) cellular lipid metabolic process [GO:0044255]; medium-chain fatty acid biosynthetic process [GO:0051792]; medium-chain fatty acid catabolic process [GO:0051793]; phosphatidylcholine biosynthetic process [GO:0006656]; phosphatidylcholine metabolic process [GO:0046470] GO:0004623; GO:0005886; GO:0006656; GO:0008126; GO:0008970; GO:0034338; GO:0044255; GO:0046470; GO:0047372; GO:0051792; GO:0051793; GO:0052739; GO:0052740 34031 XM_029331374.2 5 2 0 6 2 NA NA NA NA NA NA 34032 XM_029352260.2 1098 1277 659 764 844 Q12834 1.46e-153 Cell division cycle protein 20 homolog (p55CDC) Homo sapiens (Human) anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell differentiation [GO:0030154]; cell division [GO:0051301]; mitotic sister chromatid cohesion [GO:0007064]; mitotic spindle assembly [GO:0090307]; mitotic spindle assembly checkpoint signaling [GO:0007094]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; nervous system development [GO:0007399]; positive regulation of anaphase-promoting complex-dependent catabolic process [GO:1905786]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of synapse maturation [GO:0090129]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; protein ubiquitination [GO:0016567]; regulation of dendrite development [GO:0050773]; regulation of meiotic cell cycle [GO:0051445]; regulation of meiotic nuclear division [GO:0040020]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005654; GO:0005680; GO:0005813; GO:0005819; GO:0005829; GO:0007064; GO:0007094; GO:0007346; GO:0007399; GO:0008022; GO:0008284; GO:0010997; GO:0016567; GO:0019899; GO:0030154; GO:0031145; GO:0031915; GO:0033597; GO:0040020; GO:0042826; GO:0048471; GO:0050773; GO:0051301; GO:0051444; GO:0051445; GO:0090129; GO:0090307; GO:1904668; GO:1905786; GO:1990757 34033 XM_044312322.1 0 0 0 25 0 NA NA NA NA NA NA 34034 XM_044312137.1 110 0 56 88 48 NA NA NA NA NA NA 34035 XM_029350190.2 420 94 0 0 3 A0JMV4 3.53e-72 RNA-binding protein 5-A (RNA-binding motif protein 5-A) Xenopus laevis (African clawed frog) positive regulation of apoptotic process [GO:0043065]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; spliceosomal complex assembly [GO:0000245] GO:0000245; GO:0000381; GO:0003729; GO:0005634; GO:0005681; GO:0043065; GO:0046872 34036 XM_029350190.2 420 94 0 0 3 A0JMV4 7.43e-39 RNA-binding protein 5-A (RNA-binding motif protein 5-A) Xenopus laevis (African clawed frog) positive regulation of apoptotic process [GO:0043065]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; spliceosomal complex assembly [GO:0000245] GO:0000245; GO:0000381; GO:0003729; GO:0005634; GO:0005681; GO:0043065; GO:0046872 34037 XM_029337055.2 312 223 0 397 23 Q8IVH2 3e-74 Forkhead box protein P4 (Fork head-related protein-like A) Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000785; GO:0000978; GO:0000981; GO:0001227; GO:0005634; GO:0006357; GO:0046872 34038 XM_044315316.1 0 0 33 57 245 Q9CZR2 4.26e-163 N-acetylated-alpha-linked acidic dipeptidase 2 (EC 3.4.17.21) (Glutamate carboxypeptidase III) (GCPIII) (N-acetylaspartylglutamate peptidase II) (NAAG-peptidase II) (N-acetylated-alpha-linked acidic dipeptidase II) (NAALADase II) Mus musculus (Mouse) neurotransmitter catabolic process [GO:0042135]; proteolysis [GO:0006508] GO:0004180; GO:0004181; GO:0005886; GO:0006508; GO:0008233; GO:0016020; GO:0016805; GO:0042135; GO:0046872; GO:0050129 34039 XR_006393931.1 61 66 143 47 98 NA NA NA NA NA NA 34040 XM_029343562.2 0 0 0 0 187 Q569T7 6.98e-53 Sodium-dependent glucose transporter 1 (Major facilitator superfamily domain-containing protein 4B) Xenopus laevis (African clawed frog) carbohydrate transport [GO:0008643]; sodium ion transport [GO:0006814] GO:0006814; GO:0008643; GO:0015293; GO:0016324 34041 XR_006397187.1 919 1023 342 320 511 NA NA NA NA NA NA 34042 XM_029333336.2 0 25 0 68 295 NA NA NA NA NA NA 34043 XM_029337902.2 239 37 99 171 306 Q4R5T4 1.37e-102 RING finger protein 32 Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0005737; GO:0046872 34044 XM_044311966.1 657 880 245 1214 513 F1PZV2 1.68e-75 Major facilitator superfamily domain-containing protein 12 Canis lupus familiaris (Dog) (Canis familiaris) carbohydrate transport [GO:0008643]; cysteine transmembrane transport [GO:1903712]; melanin biosynthetic process [GO:0042438]; organic substance transport [GO:0071702]; pigment metabolic process involved in pigmentation [GO:0043474]; regulation of melanin biosynthetic process [GO:0048021] GO:0005764; GO:0005765; GO:0005886; GO:0008643; GO:0015293; GO:0033162; GO:0033229; GO:0042438; GO:0043474; GO:0048021; GO:0071702; GO:1903712 34045 XM_044306867.1 50 65 31 36 52 O43854 1.03e-85 EGF-like repeat and discoidin I-like domain-containing protein 3 (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1) Homo sapiens (Human) cell adhesion [GO:0007155]; positive regulation of cell-substrate adhesion [GO:0010811] GO:0005178; GO:0005509; GO:0007155; GO:0010811; GO:0062023; GO:0070062; GO:1903561 34046 XM_044306867.1 50 65 31 36 52 O43854 9.8e-25 EGF-like repeat and discoidin I-like domain-containing protein 3 (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1) Homo sapiens (Human) cell adhesion [GO:0007155]; positive regulation of cell-substrate adhesion [GO:0010811] GO:0005178; GO:0005509; GO:0007155; GO:0010811; GO:0062023; GO:0070062; GO:1903561 34047 XM_044310078.1 8 0 0 0 3 NA NA NA NA NA NA 34048 XM_029350976.2 0 2 171 257 244 NA NA NA NA NA NA 34049 XM_029330336.2 286 165 151 239 268 NA NA NA NA NA NA 34050 XR_006393930.1 17 705 413 846 165 NA NA NA NA NA NA 34051 XM_029334902.2 175 127 171 274 396 Q29498 0 Nitric oxide synthase, brain (EC 1.14.13.39) (BNOS) (Constitutive NOS) (NC-NOS) (NOS type I) (Neuronal NOS) (N-NOS) (NNOS) (Peptidyl-cysteine S-nitrosylase NOS1) Ovis aries (Sheep) NA GO:0004517; GO:0005516; GO:0042383; GO:0043197; GO:0046872 34052 XM_029338659.2 665 536 504 637 758 Q3UVG3 0 Protein FAM91A1 Mus musculus (Mouse) intracellular protein transport [GO:0006886]; vesicle tethering to Golgi [GO:0099041] GO:0005802; GO:0006886; GO:0031410; GO:0099041 34053 XM_029331853.2 577 476 309 598 520 Q6ZT07 0 TBC1 domain family member 9 (TBC1 domain family member 9A) Homo sapiens (Human) activation of GTPase activity [GO:0090630] GO:0005096; GO:0005509; GO:0090630 34054 XM_044318497.1 105 78 68 191 52 Q9ULT8 0 E3 ubiquitin-protein ligase HECTD1 (EC 2.3.2.26) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1) Homo sapiens (Human) anatomical structure development [GO:0048856]; aorta development [GO:0035904]; heart valve development [GO:0003170]; natural killer cell differentiation [GO:0001779]; negative regulation of protein localization to plasma membrane [GO:1903077]; neural tube closure [GO:0001843]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein localization to plasma membrane [GO:0072659]; protein polyubiquitination [GO:0000209]; spongiotrophoblast differentiation [GO:0060708]; trophoblast giant cell differentiation [GO:0060707]; ventricular septum development [GO:0003281] GO:0000209; GO:0001779; GO:0001843; GO:0003170; GO:0003281; GO:0016607; GO:0032436; GO:0035904; GO:0043161; GO:0046872; GO:0048856; GO:0051865; GO:0060707; GO:0060708; GO:0061630; GO:0070534; GO:0072659; GO:1903077 34055 XM_044318497.1 105 78 68 191 52 Q9ULT8 2e-164 E3 ubiquitin-protein ligase HECTD1 (EC 2.3.2.26) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1) Homo sapiens (Human) anatomical structure development [GO:0048856]; aorta development [GO:0035904]; heart valve development [GO:0003170]; natural killer cell differentiation [GO:0001779]; negative regulation of protein localization to plasma membrane [GO:1903077]; neural tube closure [GO:0001843]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein localization to plasma membrane [GO:0072659]; protein polyubiquitination [GO:0000209]; spongiotrophoblast differentiation [GO:0060708]; trophoblast giant cell differentiation [GO:0060707]; ventricular septum development [GO:0003281] GO:0000209; GO:0001779; GO:0001843; GO:0003170; GO:0003281; GO:0016607; GO:0032436; GO:0035904; GO:0043161; GO:0046872; GO:0048856; GO:0051865; GO:0060707; GO:0060708; GO:0061630; GO:0070534; GO:0072659; GO:1903077 34056 XM_044318497.1 105 78 68 191 52 Q9ULT8 2.33e-103 E3 ubiquitin-protein ligase HECTD1 (EC 2.3.2.26) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1) Homo sapiens (Human) anatomical structure development [GO:0048856]; aorta development [GO:0035904]; heart valve development [GO:0003170]; natural killer cell differentiation [GO:0001779]; negative regulation of protein localization to plasma membrane [GO:1903077]; neural tube closure [GO:0001843]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein localization to plasma membrane [GO:0072659]; protein polyubiquitination [GO:0000209]; spongiotrophoblast differentiation [GO:0060708]; trophoblast giant cell differentiation [GO:0060707]; ventricular septum development [GO:0003281] GO:0000209; GO:0001779; GO:0001843; GO:0003170; GO:0003281; GO:0016607; GO:0032436; GO:0035904; GO:0043161; GO:0046872; GO:0048856; GO:0051865; GO:0060707; GO:0060708; GO:0061630; GO:0070534; GO:0072659; GO:1903077 34057 XM_029345454.2 356 273 263 286 394 Q4G0U5 1.29e-166 Cilia- and flagella-associated protein 221 (Primary ciliary dyskinesia protein 1) Homo sapiens (Human) cerebrospinal fluid circulation [GO:0090660]; cilium assembly [GO:0060271]; establishment of localization in cell [GO:0051649]; motile cilium assembly [GO:0044458]; mucociliary clearance [GO:0120197]; sperm flagellum assembly [GO:0120316] GO:0002177; GO:0005516; GO:0005576; GO:0005737; GO:0005929; GO:0005930; GO:0036126; GO:0044458; GO:0051649; GO:0060271; GO:0090660; GO:0097729; GO:0120197; GO:0120316 34058 XM_044308475.1 53 16 56 68 161 NA NA NA NA NA NA 34059 XM_044312031.1 7 30 17 3 225 NA NA NA NA NA NA 34060 XM_044311429.1 93 39 41 64 40 Q9NBX4 3.25e-23 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 34061 XM_029351303.2 140 222 106 280 335 NA NA NA NA NA NA 34062 XM_044319885.1 5 3 1 12 8 NA NA NA NA NA NA 34063 XM_044307637.1 0 0 0 0 6 P79385 3.28e-23 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (SED1) (Sperm surface protein SP47) (PP47) Sus scrofa (Pig) angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; single fertilization [GO:0007338] GO:0001525; GO:0002080; GO:0005576; GO:0007155; GO:0007338 34064 XM_029329417.2 227 228 50 200 72 NA NA NA NA NA NA 34065 XM_029355533.2 18 27 18 29 47 NA NA NA NA NA NA 34066 XM_044312887.1 24 2 3 0 0 NA NA NA NA NA NA 34067 XR_003823899.2 345 287 233 348 551 NA NA NA NA NA NA 34068 XM_029358611.2 463 393 141 471 608 Q6P3X3 0 Tetratricopeptide repeat protein 27 (TPR repeat protein 27) Homo sapiens (Human) NA NA 34069 XM_029353670.2 196 370 89 919 216 NA NA NA NA NA NA 34070 XM_029356168.2 10 0 0 6 0 Q96A58 1.8e-36 Ras-related and estrogen-regulated growth inhibitor (EC 3.6.5.2) Homo sapiens (Human) negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; Ras protein signal transduction [GO:0007265]; response to hormone [GO:0009725]; small GTPase mediated signal transduction [GO:0007264] GO:0001650; GO:0003924; GO:0003925; GO:0005525; GO:0005634; GO:0005654; GO:0005829; GO:0005886; GO:0007264; GO:0007265; GO:0008285; GO:0009725; GO:0019003; GO:0030308; GO:0030331 34071 XM_029358442.2 731 178 31 832 415 Q80VW5 7.16e-103 Whirlin Mus musculus (Mouse) auditory receptor cell stereocilium organization [GO:0060088]; cerebellar Purkinje cell layer formation [GO:0021694]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; inner ear receptor cell differentiation [GO:0060113]; inner ear receptor cell stereocilium organization [GO:0060122]; paranodal junction maintenance [GO:1990227]; positive regulation of gene expression [GO:0010628]; retina homeostasis [GO:0001895]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605] GO:0001895; GO:0001917; GO:0002141; GO:0002142; GO:0005737; GO:0005829; GO:0005884; GO:0005886; GO:0005929; GO:0007605; GO:0010628; GO:0016020; GO:0019904; GO:0021694; GO:0030426; GO:0032391; GO:0032420; GO:0032421; GO:0032426; GO:0036064; GO:0042802; GO:0043005; GO:0043025; GO:0043198; GO:0044303; GO:0045184; GO:0048471; GO:0050910; GO:0050953; GO:0051649; GO:0060088; GO:0060113; GO:0060122; GO:0097440; GO:0098793; GO:0098794; GO:1990075; GO:1990227; GO:1990696 34072 XM_029334817.2 0 0 0 0 68 NA NA NA NA NA NA 34073 XR_006391735.1 123 88 169 172 85 NA NA NA NA NA NA 34074 XM_029330029.2 6 1 28 0 137 O18276 2.22e-59 Gamma-aminobutyric acid receptor subunit beta (GABA(A) receptor subunit beta) Caenorhabditis elegans chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165] GO:0004890; GO:0005230; GO:0005231; GO:0005254; GO:0005886; GO:0006811; GO:0007165; GO:0007268; GO:0030594; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:1902476; GO:1902711; GO:1904315 34075 XM_029353668.2 0 0 0 0 10 P25931 1.53e-23 RYamide receptor (Neuropeptide Y-like receptor) (NPY-R) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218] GO:0001653; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0016020 34076 XM_044317640.1 1431 1049 694 1080 793 Q8CG45 2.44e-110 Aflatoxin B1 aldehyde reductase member 2 (rAFAR2) (EC 1.1.1.n11) (Succinic semialdehyde reductase) (SSA reductase) Rattus norvegicus (Rat) daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; lipid metabolic process [GO:0006629] GO:0004032; GO:0004033; GO:0005635; GO:0005737; GO:0005739; GO:0005794; GO:0005795; GO:0006629; GO:0019119; GO:0044597; GO:0044598 34077 XM_044307878.1 0 0 0 21 6 NA NA NA NA NA NA 34078 XM_029345473.2 0 0 0 14 0 Q5NU32 1.26e-84 Amine oxidase [flavin-containing] A (EC 1.4.3.21) (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A) Equus caballus (Horse) catecholamine metabolic process [GO:0006584]; neurotransmitter catabolic process [GO:0042135] GO:0005739; GO:0005741; GO:0006584; GO:0008131; GO:0042135; GO:0050660; GO:0052595; GO:0052596; GO:0097621 34079 XM_029329192.2 1242 1246 798 988 733 Q0P5A1 2.5e-27 Dynactin subunit 3 Bos taurus (Bovine) cytoskeleton-dependent cytokinesis [GO:0061640]; microtubule-based process [GO:0007017] GO:0000776; GO:0005730; GO:0005813; GO:0005819; GO:0005829; GO:0005869; GO:0007017; GO:0030496; GO:0032154; GO:0048471; GO:0061640 34080 XR_006392205.1 451 271 326 383 467 NA NA NA NA NA NA 34081 XM_029330731.2 684 541 577 539 825 Q8CGC6 3.12e-60 RNA-binding protein 28 (RNA-binding motif protein 28) Mus musculus (Mouse) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0003723; GO:0005681; GO:0005730; GO:0006397; GO:0008380 34082 XM_029332214.2 368 248 176 422 408 Q8R323 0 Replication factor C subunit 3 (Activator 1 38 kDa subunit) (A1 38 kDa subunit) (Activator 1 subunit 3) (Replication factor C 38 kDa subunit) (RF-C 38 kDa subunit) (RFC38) Mus musculus (Mouse) DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA-templated DNA replication [GO:0006261]; positive regulation of DNA-directed DNA polymerase activity [GO:1900264]; response to organophosphorus [GO:0046683] GO:0003677; GO:0003689; GO:0005634; GO:0005663; GO:0006260; GO:0006261; GO:0006281; GO:0008094; GO:0017116; GO:0031390; GO:0046683; GO:1900264 34083 XM_044316715.1 41 17 37 86 95 D8VNT0 3.23e-54 Ryncolin-4 Cerberus rynchops (Dog-faced water snake) NA GO:0005576; GO:0090729 34084 XM_029344267.2 1709 1964 1127 704 817 Q8RYE9 9.34e-41 Haloacid dehalogenase-like hydrolase domain-containing protein At2g33255 (EC 3.1.3.-) Arabidopsis thaliana (Mouse-ear cress) NA GO:0005783; GO:0005829; GO:0009507; GO:0016791; GO:0046872 34085 XM_044329324.1 79 27 50 64 73 NA NA NA NA NA NA 34086 XM_044318081.1 6 0 0 7 6 NA NA NA NA NA NA 34087 XM_029348718.2 0 0 0 48 0 Q6AYE3 7.51e-130 Transcriptional adapter 2-alpha (Transcriptional adapter 2-like) (ADA2-like protein) Rattus norvegicus (Rat) chromatin remodeling [GO:0006338]; histone H3 acetylation [GO:0043966]; histone H3-K14 acetylation [GO:0044154]; mitotic cell cycle [GO:0000278]; positive regulation of histone acetylation [GO:0035066]; regulation of cell cycle [GO:0051726]; regulation of cell division [GO:0051302]; regulation of DNA-templated transcription [GO:0006355]; regulation of embryonic development [GO:0045995]; regulation of histone deacetylation [GO:0031063]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tubulin deacetylation [GO:0090043] GO:0000124; GO:0000278; GO:0001932; GO:0003677; GO:0003682; GO:0003713; GO:0005634; GO:0006338; GO:0006355; GO:0006357; GO:0008270; GO:0031063; GO:0031647; GO:0035066; GO:0043966; GO:0044154; GO:0045995; GO:0051302; GO:0051726; GO:0070461; GO:0072686; GO:0090043; GO:0140672 34088 XM_029324197.2 855 981 497 584 562 O14733 2.47e-154 Dual specificity mitogen-activated protein kinase kinase 7 (MAP kinase kinase 7) (MAPKK 7) (EC 2.7.12.2) (JNK-activating kinase 2) (MAPK/ERK kinase 7) (MEK 7) (Stress-activated protein kinase kinase 4) (SAPK kinase 4) (SAPKK-4) (SAPKK4) (c-Jun N-terminal kinase kinase 2) (JNK kinase 2) (JNKK 2) Homo sapiens (Human) apoptotic process [GO:0006915]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to sorbitol [GO:0072709]; cellular senescence [GO:0090398]; Fc-epsilon receptor signaling pathway [GO:0038095]; JNK cascade [GO:0007254]; MAPK cascade [GO:0000165]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of motor neuron apoptotic process [GO:2000671]; response to heat [GO:0009408]; response to osmotic stress [GO:0006970]; response to tumor necrosis factor [GO:0034612]; response to UV [GO:0009411]; response to wounding [GO:0009611]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403] GO:0000165; GO:0000287; GO:0004707; GO:0004708; GO:0004713; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006915; GO:0006970; GO:0007165; GO:0007254; GO:0008022; GO:0008545; GO:0009408; GO:0009411; GO:0009611; GO:0019899; GO:0019901; GO:0019903; GO:0031435; GO:0032212; GO:0034612; GO:0038095; GO:0043507; GO:0043525; GO:0045893; GO:0046330; GO:0051403; GO:0051973; GO:0070374; GO:0071222; GO:0071347; GO:0072709; GO:0090398; GO:0106310; GO:0140677; GO:1904355; GO:2000671 34089 XM_044317988.1 132 76 34 77 142 Q9NWS8 7.73e-77 Required for meiotic nuclear division protein 1 homolog Homo sapiens (Human) positive regulation of mitochondrial translation [GO:0070131]; translation [GO:0006412] GO:0005739; GO:0006412; GO:0070131 34090 XM_029323882.2 0 0 25 0 0 NA NA NA NA NA NA 34091 XM_044328545.1 22 2 8 0 21 NA NA NA NA NA NA 34092 XM_029323601.2 588 288 405 418 460 Q66J74 0 Tuftelin-interacting protein 11 (Septin and tuftelin-interacting protein 1) (STIP-1) Xenopus laevis (African clawed frog) spliceosomal complex disassembly [GO:0000390] GO:0000390; GO:0003676; GO:0005681 34093 XM_029323694.2 1859 1527 1056 1519 1253 Q3UHD6 6.18e-168 Sorting nexin-27 Mus musculus (Mouse) endocytic recycling [GO:0032456]; endosomal transport [GO:0016197]; endosome to lysosome transport [GO:0008333]; endosome to plasma membrane protein transport [GO:0099638]; establishment of protein localization to plasma membrane [GO:0061951]; intracellular protein transport [GO:0006886]; negative regulation of inward rectifier potassium channel activity [GO:1903609]; positive regulation of AMPA glutamate receptor clustering [GO:1904719]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; signal transduction [GO:0007165] GO:0001772; GO:0005768; GO:0005769; GO:0005829; GO:0005886; GO:0006886; GO:0007165; GO:0008333; GO:0014069; GO:0016197; GO:0030904; GO:0031901; GO:0032266; GO:0032456; GO:0035091; GO:0035255; GO:0061951; GO:0071203; GO:0098685; GO:0098978; GO:0099072; GO:0099638; GO:1903609; GO:1904719 34094 XM_029347233.2 65 0 79 47 69 NA NA NA NA NA NA 34095 XM_029329710.2 394 134 103 90 143 NA NA NA NA NA NA 34096 XR_003828474.2 1 17 8 46 20 NA NA NA NA NA NA 34097 XM_044317610.1 5 0 19 11 54 NA NA NA NA NA NA 34098 XR_006391390.1 0 0 13 15 26 NA NA NA NA NA NA 34099 XM_029329866.2 180 19 136 632 295 P20072 1.2e-70 Annexin A7 (Annexin VII) (Annexin-7) (Synexin) Bos taurus (Bovine) NA GO:0005509; GO:0005544; GO:0005634; GO:0005737; GO:0042584 34100 XM_044326047.1 15 5 7 50 1 NA NA NA NA NA NA 34101 XM_044309255.1 5 7 6 2 18 NA NA NA NA NA NA 34102 XM_044327799.1 43 27 21 42 35 O88488 1.43e-48 Phosphatidylinositol phosphatase PTPRQ (EC 3.1.3.-) (Protein-tyrosine phosphatase receptor-type expressed by glomerular mesangial cells protein 1) (rPTP-GMC1) (Receptor-type tyrosine-protein phosphatase Q) (PTP-RQ) (R-PTP-Q) (EC 3.1.3.48) Rattus norvegicus (Rat) detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; hematopoietic progenitor cell differentiation [GO:0002244]; inner ear morphogenesis [GO:0042472]; neuromuscular process controlling balance [GO:0050885]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; regulation of fat cell differentiation [GO:0045598]; vestibular receptor cell morphogenesis [GO:0060116] GO:0002244; GO:0004725; GO:0005886; GO:0032421; GO:0042472; GO:0043235; GO:0045598; GO:0050885; GO:0050910; GO:0060116; GO:1990264 34103 XM_044327799.1 43 27 21 42 35 O88488 6.08e-34 Phosphatidylinositol phosphatase PTPRQ (EC 3.1.3.-) (Protein-tyrosine phosphatase receptor-type expressed by glomerular mesangial cells protein 1) (rPTP-GMC1) (Receptor-type tyrosine-protein phosphatase Q) (PTP-RQ) (R-PTP-Q) (EC 3.1.3.48) Rattus norvegicus (Rat) detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; hematopoietic progenitor cell differentiation [GO:0002244]; inner ear morphogenesis [GO:0042472]; neuromuscular process controlling balance [GO:0050885]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; regulation of fat cell differentiation [GO:0045598]; vestibular receptor cell morphogenesis [GO:0060116] GO:0002244; GO:0004725; GO:0005886; GO:0032421; GO:0042472; GO:0043235; GO:0045598; GO:0050885; GO:0050910; GO:0060116; GO:1990264 34104 XM_044327799.1 43 27 21 42 35 O88488 7.68e-27 Phosphatidylinositol phosphatase PTPRQ (EC 3.1.3.-) (Protein-tyrosine phosphatase receptor-type expressed by glomerular mesangial cells protein 1) (rPTP-GMC1) (Receptor-type tyrosine-protein phosphatase Q) (PTP-RQ) (R-PTP-Q) (EC 3.1.3.48) Rattus norvegicus (Rat) detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; hematopoietic progenitor cell differentiation [GO:0002244]; inner ear morphogenesis [GO:0042472]; neuromuscular process controlling balance [GO:0050885]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; regulation of fat cell differentiation [GO:0045598]; vestibular receptor cell morphogenesis [GO:0060116] GO:0002244; GO:0004725; GO:0005886; GO:0032421; GO:0042472; GO:0043235; GO:0045598; GO:0050885; GO:0050910; GO:0060116; GO:1990264 34105 XM_044319532.1 8 4 11 1 25 Q9UHC6 6.46e-34 Contactin-associated protein-like 2 (Cell recognition molecule Caspr2) Homo sapiens (Human) adult behavior [GO:0030534]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell population proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; clustering of voltage-gated potassium channels [GO:0045163]; learning [GO:0007612]; limbic system development [GO:0021761]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuron recognition [GO:0008038]; positive regulation of gap junction assembly [GO:1903598]; protein localization to juxtaparanode region of axon [GO:0071205]; social behavior [GO:0035176]; striatum development [GO:0021756]; superior temporal gyrus development [GO:0071109]; thalamus development [GO:0021794]; transmission of nerve impulse [GO:0019226]; vocal learning [GO:0042297]; vocalization behavior [GO:0071625] GO:0005769; GO:0005794; GO:0007155; GO:0007420; GO:0007612; GO:0008038; GO:0008076; GO:0008283; GO:0009986; GO:0016020; GO:0019226; GO:0019899; GO:0021756; GO:0021761; GO:0021794; GO:0021987; GO:0030424; GO:0030425; GO:0030534; GO:0030673; GO:0031175; GO:0033010; GO:0035176; GO:0042297; GO:0043025; GO:0043204; GO:0044224; GO:0045163; GO:0048812; GO:0071109; GO:0071205; GO:0071625; GO:1903598 34106 XM_029329283.2 2191 1306 1098 1199 1136 Q96BD5 2.01e-57 PHD finger protein 21A (BHC80a) (BRAF35-HDAC complex protein BHC80) Homo sapiens (Human) chromatin organization [GO:0006325]; negative regulation of transcription by RNA polymerase II [GO:0000122] GO:0000118; GO:0000122; GO:0003677; GO:0003682; GO:0005654; GO:0006325; GO:0046872; GO:1990391 34107 XM_029323409.2 4883 5978 3461 6569 4670 NA NA NA NA NA NA 34108 XR_006395267.1 45 315 83 108 174 NA NA NA NA NA NA 34109 XM_029346869.2 291 289 112 231 184 Q587K4 8.98e-69 Leucine-rich repeat-containing protein 73 (NOD3-like protein) Rattus norvegicus (Rat) NA NA 34110 XM_029347397.2 1723 902 1127 1553 1687 Q8IUD2 8.19e-72 ELKS/Rab6-interacting/CAST family member 1 (ERC-1) (Rab6-interacting protein 2) Homo sapiens (Human) I-kappaB phosphorylation [GO:0007252]; maintenance of presynaptic active zone structure [GO:0048790]; neuromuscular synaptic transmission [GO:0007274]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein transport [GO:0015031]; regulation of DNA-templated transcription [GO:0006355]; regulation of synaptic plasticity [GO:0048167]; retrograde transport, endosome to Golgi [GO:0042147] GO:0000139; GO:0005737; GO:0005813; GO:0006355; GO:0007252; GO:0007274; GO:0008385; GO:0015031; GO:0030165; GO:0031267; GO:0036064; GO:0042147; GO:0042734; GO:0045202; GO:0045296; GO:0048167; GO:0048788; GO:0048790; GO:0051092; GO:0098882 34111 XM_029338427.2 16864 13923 10465 18907 15670 P48727 0 Serine/threonine-protein phosphatase PP1-beta (EC 3.1.3.16) (CeGLC-7-beta) (Glc seven-like phosphatase 2) Caenorhabditis elegans cell division [GO:0051301]; chromatin organization [GO:0006325]; meiotic cell cycle [GO:0051321]; peptidyl-serine dephosphorylation [GO:0070262] GO:0004722; GO:0005634; GO:0005694; GO:0005737; GO:0006325; GO:0017018; GO:0031965; GO:0046872; GO:0051301; GO:0051321; GO:0070262 34112 XM_029339899.2 0 0 0 11 0 NA NA NA NA NA NA 34113 XM_029333779.2 0 0 0 77 87 Q7TN88 2.84e-68 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 34114 XM_029333779.2 0 0 0 77 87 Q7TN88 2.83e-49 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 34115 XM_044327211.1 88 41 59 124 101 NA NA NA NA NA NA 34116 XM_044326898.1 1783 1149 1034 1817 1514 Q96MY1 8.27e-29 Nucleolar protein 4-like Homo sapiens (Human) NA GO:0005654; GO:0005829 34117 XR_003824787.2 19 38 68 20 79 NA NA NA NA NA NA 34118 XR_006395932.1 35 47 6 88 71 NA NA NA NA NA NA 34119 XM_029354139.2 653 403 369 711 821 NA NA NA NA NA NA 34120 XM_029355528.2 0 112 91 86 0 Q7ZWE3 1.58e-66 La-related protein 7 (La ribonucleoprotein domain family member 7) Danio rerio (Zebrafish) (Brachydanio rerio) box C/D RNA 3'-end processing [GO:0000494]; cardiac muscle tissue regeneration [GO:0061026]; cell differentiation [GO:0030154]; mRNA processing [GO:0006397]; positive regulation of protein localization to Cajal body [GO:1904871]; positive regulation of snRNA transcription by RNA polymerase II [GO:1905382]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of mRNA splicing, via spliceosome [GO:0048024]; RNA splicing [GO:0008380]; spermatogenesis [GO:0007283]; U6 2'-O-snRNA methylation [GO:1990438] GO:0000494; GO:0003723; GO:0005634; GO:0005654; GO:0006397; GO:0007283; GO:0008380; GO:0017070; GO:0030154; GO:0030532; GO:0048024; GO:0060043; GO:0061026; GO:0097322; GO:1904871; GO:1905382; GO:1990438; GO:1990904 34121 XM_044320926.1 0 84 0 0 0 NA NA NA NA NA NA 34122 XM_044323498.1 114 0 0 163 32 P21137 8.48e-22 cAMP-dependent protein kinase catalytic subunit (PKA C) (EC 2.7.11.11) Caenorhabditis elegans positive regulation of oocyte maturation [GO:1900195]; protein kinase A signaling [GO:0010737]; protein phosphorylation [GO:0006468] GO:0004679; GO:0004691; GO:0005524; GO:0005634; GO:0005952; GO:0006468; GO:0010737; GO:0106310; GO:1900195 34123 XM_044323498.1 114 0 0 163 32 P21137 8.48e-22 cAMP-dependent protein kinase catalytic subunit (PKA C) (EC 2.7.11.11) Caenorhabditis elegans positive regulation of oocyte maturation [GO:1900195]; protein kinase A signaling [GO:0010737]; protein phosphorylation [GO:0006468] GO:0004679; GO:0004691; GO:0005524; GO:0005634; GO:0005952; GO:0006468; GO:0010737; GO:0106310; GO:1900195 34124 XR_006392811.1 37 13 54 39 7 NA NA NA NA NA NA 34125 XM_044311351.1 0 5 30 0 0 NA NA NA NA NA NA 34126 XM_029340921.2 168 194 243 609 380 Q6TH22 1.21e-141 Protein DDI1 homolog 2 (EC 3.4.23.-) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to hydroxyurea [GO:0072711]; proteasomal protein catabolic process [GO:0010498]; protein processing [GO:0016485]; regulation of DNA stability [GO:0097752]; regulation of protein stability [GO:0031647] GO:0004190; GO:0005694; GO:0005829; GO:0010498; GO:0016485; GO:0031647; GO:0042802; GO:0072711; GO:0097752 34127 XM_044314663.1 55 15 0 0 94 NA NA NA NA NA NA 34128 XM_029339115.2 3229 2331 1872 2757 2074 O88407 5.79e-41 Protein lifeguard 2 (Fas apoptotic inhibitory molecule 2) (Neural membrane protein 35) Rattus norvegicus (Rat) apoptotic signaling pathway [GO:0097190]; central nervous system development [GO:0007417]; cerebellar granular layer development [GO:0021681]; cerebellar Purkinje cell differentiation [GO:0021702]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum development [GO:0021549]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of neuron apoptotic process [GO:0043524]; neuron apoptotic process [GO:0051402]; regulation of neuron apoptotic process [GO:0043523]; response to ischemia [GO:0002931] GO:0002931; GO:0005783; GO:0005794; GO:0007417; GO:0016020; GO:0021549; GO:0021680; GO:0021681; GO:0021702; GO:0043523; GO:0043524; GO:0045121; GO:0045211; GO:0051402; GO:0097190; GO:1902042; GO:2001234 34129 XM_029348932.2 164 38 67 441 143 P50571 6.42e-78 Gamma-aminobutyric acid receptor subunit beta-1 (GABA(A) receptor subunit beta-1) Mus musculus (Mouse) cellular response to histamine [GO:0071420]; central nervous system neuron development [GO:0021954]; chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid signaling pathway [GO:0007214]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; nervous system process [GO:0050877]; ovulation cycle [GO:0042698]; regulation of membrane potential [GO:0042391]; response to progesterone [GO:0032570]; response to toxic substance [GO:0009636]; signal transduction [GO:0007165] GO:0004890; GO:0005231; GO:0005253; GO:0005634; GO:0005635; GO:0005737; GO:0005886; GO:0006811; GO:0007165; GO:0007214; GO:0007268; GO:0009636; GO:0015276; GO:0016020; GO:0021954; GO:0022851; GO:0030425; GO:0030594; GO:0032570; GO:0034220; GO:0034707; GO:0042391; GO:0042698; GO:0043005; GO:0043235; GO:0045202; GO:0048787; GO:0050811; GO:0050877; GO:0071420; GO:0098685; GO:0098982; GO:0099507; GO:0099634; GO:0150047; GO:1902476; GO:1902711; GO:1904315 34130 XM_029327105.2 0 217 190 0 6 NA NA NA NA NA NA 34131 XM_044307635.1 20 50 14 3 4 P79385 2.14e-28 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (SED1) (Sperm surface protein SP47) (PP47) Sus scrofa (Pig) angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; single fertilization [GO:0007338] GO:0001525; GO:0002080; GO:0005576; GO:0007155; GO:0007338 34132 XM_029330693.2 5 28 0 0 16 Q9D0S4 1.5e-30 Neuralized-like protein 2 Mus musculus (Mouse) intracellular signal transduction [GO:0035556]; myofibril assembly [GO:0030239]; sarcomere organization [GO:0045214] GO:0005927; GO:0030239; GO:0030891; GO:0035556; GO:0045214; GO:0061630 34133 XM_029329250.2 51 20 38 59 54 NA NA NA NA NA NA 34134 XM_044316187.1 119 229 166 109 279 Q69CM7 7e-34 MYCBP-associated protein (Organ of Corti membrane-associated protein of 106 kDa) Rattus norvegicus (Rat) cell differentiation [GO:0030154]; chemical synaptic transmission [GO:0007268]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283] GO:0005737; GO:0007268; GO:0007283; GO:0007605; GO:0019897; GO:0030154 34135 XM_029348798.2 430 210 142 262 256 NA NA NA NA NA NA 34136 XM_029351132.2 33 8 12 12 20 NA NA NA NA NA NA 34137 XM_029329529.2 2690 1505 848 5390 3936 NA NA NA NA NA NA 34138 XM_029342577.2 2055 1512 1231 1946 1695 Q5NVI9 2.09e-178 DnaJ homolog subfamily A member 1 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) negative regulation of apoptotic process [GO:0043066]; negative regulation of JUN kinase activity [GO:0043508]; positive regulation of apoptotic process [GO:0043065]; protein folding [GO:0006457]; protein localization to mitochondrion [GO:0070585]; regulation of protein transport [GO:0051223]; response to heat [GO:0009408] GO:0001671; GO:0005524; GO:0005634; GO:0005739; GO:0005783; GO:0006457; GO:0009408; GO:0016020; GO:0030544; GO:0043065; GO:0043066; GO:0043508; GO:0046872; GO:0048471; GO:0051082; GO:0051087; GO:0051223; GO:0070585 34139 XM_029327132.2 0 0 7 0 4 Q923X6 6.61e-24 Trace amine-associated receptor 7e (TaR-7e) (Trace amine receptor 7e) (Trace amine receptor 14) (TaR-14) Rattus norvegicus (Rat) NA GO:0001594; GO:0005886 34140 XM_029357555.2 2715 11508 3938 6656 4665 Q9GZQ3 5.02e-40 COMM domain-containing protein 5 (Hypertension-related calcium-regulated gene protein) (HCaRG) Homo sapiens (Human) NA GO:0005634; GO:0005654; GO:0005829 34141 XM_029351442.2 132 65 88 67 164 B8VIU6 1.4e-56 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 34142 XM_044321335.1 45 18 27 19 31 NA NA NA NA NA NA 34143 XM_029353814.2 2618 1783 1839 1773 1333 Q32LP4 0 Sodium-driven chloride bicarbonate exchanger (Solute carrier family 4 member 10) Bos taurus (Bovine) bicarbonate transport [GO:0015701]; brain morphogenesis [GO:0048854]; ion homeostasis [GO:0050801]; locomotory exploration behavior [GO:0035641]; multicellular organism growth [GO:0035264]; post-embryonic development [GO:0009791]; proton transmembrane transport [GO:1902600]; pyramidal neuron development [GO:0021860]; regulation of intracellular pH [GO:0051453]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; response to light stimulus [GO:0009416]; transmembrane transport [GO:0055085]; visual perception [GO:0007601] GO:0005886; GO:0007601; GO:0008510; GO:0009416; GO:0009791; GO:0015701; GO:0016323; GO:0016324; GO:0021860; GO:0022857; GO:0030425; GO:0035264; GO:0035641; GO:0036477; GO:0043025; GO:0043204; GO:0043679; GO:0045202; GO:0048172; GO:0048854; GO:0050801; GO:0051453; GO:0055085; GO:0097440; GO:0097441; GO:0097442; GO:0098794; GO:0140892; GO:1902600 34144 XR_003826216.2 800 748 579 1472 1009 NA NA NA NA NA NA 34145 XM_029333292.2 689 574 471 539 544 NA NA NA NA NA NA 34146 XM_029333984.2 401 338 39 451 393 Q498L0 1.08e-22 Centrosomal protein of 170 kDa protein B (Centrosomal protein 170B) (Cep170B) Xenopus laevis (African clawed frog) NA GO:0005737; GO:0005874 34147 XM_029344204.2 39 36 36 17 186 NA NA NA NA NA NA 34148 XM_044308785.1 460 6 909 104 377 A0A1B4XBH3 3.58e-155 Highly reducing polyketide synthase sdnO (EC 2.3.1.-) (Sordarin/hypoxysordarin biosynthesis cluster protein O) Sordaria araneosa (Pleurage araneosa) antibiotic biosynthetic process [GO:0017000]; organic substance biosynthetic process [GO:1901576] GO:0016491; GO:0016746; GO:0017000; GO:0031177; GO:1901576 34149 XM_044307696.1 726 574 411 891 827 NA NA NA NA NA NA 34150 XM_044325243.1 2059 1075 875 2967 3210 Q61093 1.66e-179 Cytochrome b-245 heavy chain (EC 1.-.-.-) (CGD91-phox) (Cytochrome b(558) subunit beta) (Cytochrome b558 subunit beta) (Heme-binding membrane glycoprotein gp91phox) (Neutrophil cytochrome b 91 kDa polypeptide) (gp91-1) (gp91-phox) (p22 phagocyte B-cytochrome) Mus musculus (Mouse) cellular response to cadmium ion [GO:0071276]; cellular response to ethanol [GO:0071361]; cellular response to L-glutamine [GO:1904845]; defense response [GO:0006952]; hydrogen peroxide biosynthetic process [GO:0050665]; hypoxia-inducible factor-1alpha signaling pathway [GO:0097411]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; positive regulation of angiogenesis [GO:0045766]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of ion transmembrane transport [GO:0034765]; respiratory burst [GO:0045730]; response to aldosterone [GO:1904044]; response to angiotensin [GO:1990776]; response to nutrient [GO:0007584]; response to xenobiotic stimulus [GO:0009410]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801] GO:0005244; GO:0005635; GO:0005737; GO:0005739; GO:0005783; GO:0005791; GO:0005794; GO:0005886; GO:0006801; GO:0006952; GO:0006954; GO:0007584; GO:0009055; GO:0009410; GO:0016175; GO:0020037; GO:0030425; GO:0032760; GO:0034765; GO:0042554; GO:0043020; GO:0043025; GO:0045087; GO:0045335; GO:0045730; GO:0045766; GO:0046872; GO:0046982; GO:0050660; GO:0050665; GO:0071276; GO:0071361; GO:0097038; GO:0097411; GO:1904044; GO:1904845; GO:1990776 34151 XM_029334834.2 12406 30109 20413 28750 20295 Q92843 2.19e-28 Bcl-2-like protein 2 (Bcl2-L-2) (Apoptosis regulator Bcl-W) Homo sapiens (Human) brain development [GO:0007420]; cellular response to amyloid-beta [GO:1904646]; cellular response to estradiol stimulus [GO:0071392]; cellular response to glycine [GO:1905430]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; negative regulation of apoptotic process [GO:0043066]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of mitochondrial membrane permeability [GO:0035795]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; regulation of apoptotic process [GO:0042981]; response to ischemia [GO:0002931]; Sertoli cell proliferation [GO:0060011]; spermatogenesis [GO:0007283] GO:0002931; GO:0005741; GO:0005829; GO:0007283; GO:0007420; GO:0008630; GO:0035795; GO:0042802; GO:0042803; GO:0042981; GO:0043066; GO:0044877; GO:0046982; GO:0051400; GO:0060011; GO:0071392; GO:0090201; GO:0097136; GO:0097192; GO:0097718; GO:1904646; GO:1905430; GO:2001243 34152 XM_044317181.1 1866 1661 1378 1156 1829 Q6PFL8 2.24e-81 Thymocyte nuclear protein 1 Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005634 34153 XM_029333529.2 933 1118 310 108 440 P10079 2.2e-166 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 34154 XM_029333529.2 933 1118 310 108 440 P10079 1.45e-158 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 34155 XM_029333529.2 933 1118 310 108 440 P10079 7.15e-152 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 34156 XM_029333529.2 933 1118 310 108 440 P10079 1.19e-124 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 34157 XM_044317838.1 71 101 17 61 43 NA NA NA NA NA NA 34158 XM_044316972.1 0 0 0 2 8 NA NA NA NA NA NA 34159 XM_029329635.2 946 587 609 861 754 Q3U564 9.82e-41 mRNA-decapping enzyme 1B (EC 3.6.1.62) Mus musculus (Mouse) cellular response to interleukin-17 [GO:0097398]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; deadenylation-independent decapping of nuclear-transcribed mRNA [GO:0031087]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of catalytic activity [GO:0043085]; protein localization to nucleus [GO:0034504]; protein localization to P-body [GO:0110012] GO:0000184; GO:0000290; GO:0000932; GO:0003729; GO:0005634; GO:0005829; GO:0008047; GO:0031087; GO:0034504; GO:0043085; GO:0043231; GO:0097398; GO:0110012; GO:0140933 34160 XM_044326424.1 23 47 50 97 80 NA NA NA NA NA NA 34161 XM_029344293.2 9206 9713 7199 9558 7008 Q6P8Y1 1.26e-62 Calcyphosin-like protein Mus musculus (Mouse) NA GO:0005509; GO:0005737 34162 XM_044322576.1 176 201 330 0 0 Q7RTR2 4.38e-62 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 34163 XM_044322576.1 176 201 330 0 0 Q7RTR2 2.07e-59 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 34164 XM_044322576.1 176 201 330 0 0 Q7RTR2 3.85e-56 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 34165 XM_044322576.1 176 201 330 0 0 Q7RTR2 2.92e-38 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 34166 XM_044328534.1 62 112 18 92 0 NA NA NA NA NA NA 34167 XM_029353930.2 0 10 0 0 0 D4A9K4 4.23e-65 MFS-type transporter SLC18B1 (Solute carrier family 18 member B1) (Vesicular polyamine transporter) (VPAT) Rattus norvegicus (Rat) serotonin transport [GO:0006837]; serotonin uptake [GO:0051610]; spermidine transport [GO:0015848]; spermine transport [GO:0000296] GO:0000296; GO:0006837; GO:0015311; GO:0015312; GO:0015848; GO:0022857; GO:0030667; GO:0030672; GO:0051610 34168 XM_029328007.2 2787 988 1001 827 82 NA NA NA NA NA NA 34169 XM_029346711.2 186 135 64 264 155 Q5R4J5 3.67e-27 Synaptotagmin-1 (Synaptotagmin I) (SytI) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cell differentiation [GO:0030154]; positive regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903235] GO:0030154; GO:0030672; GO:0042584; GO:0046872; GO:1903235 34170 XM_029358595.2 25 8 27 43 52 E9Q4F2 6.65e-59 Kelch-like protein 18 Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; positive regulation of mitotic cell cycle phase transition [GO:1901992]; protein ubiquitination [GO:0016567] GO:0007049; GO:0016567; GO:0051301; GO:1901992 34171 XM_029348352.2 141 182 0 139 48 NA NA NA NA NA NA 34172 XM_029330276.2 151 78 142 429 57 NA NA NA NA NA NA 34173 XM_044324092.1 0 0 5 0 11 NA NA NA NA NA NA 34174 XM_044318372.1 23 8 16 0 62 NA NA NA NA NA NA 34175 XM_029331750.2 310 204 375 275 463 NA NA NA NA NA NA 34176 XM_029324163.2 1521 1010 941 1024 1066 Q00004 4.03e-175 Signal recognition particle subunit SRP68 (SRP68) (Signal recognition particle 68 kDa protein) Canis lupus familiaris (Dog) (Canis familiaris) SRP-dependent cotranslational protein targeting to membrane [GO:0006614] GO:0005047; GO:0005730; GO:0005783; GO:0005786; GO:0005829; GO:0006614; GO:0008312; GO:0030942 34177 XR_006394770.1 12 0 1 27 7 NA NA NA NA NA NA 34178 XM_029349661.2 12 2 2 9 13 NA NA NA NA NA NA 34179 XM_029331181.2 18 0 0 0 55 P23416 4.88e-85 Glycine receptor subunit alpha-2 Homo sapiens (Human) cellular response to amino acid stimulus [GO:0071230]; cellular response to ethanol [GO:0071361]; cellular response to zinc ion [GO:0071294]; chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; neuropeptide signaling pathway [GO:0007218]; regulation of membrane potential [GO:0042391]; response to amino acid [GO:0043200]; signal transduction [GO:0007165]; synaptic transmission, glycinergic [GO:0060012] GO:0004888; GO:0005231; GO:0005886; GO:0007165; GO:0007218; GO:0007268; GO:0016594; GO:0016934; GO:0022852; GO:0030594; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0043200; GO:0045202; GO:0045211; GO:0046872; GO:0050877; GO:0060012; GO:0071230; GO:0071294; GO:0071361; GO:0098690; GO:1902476; GO:1904315 34180 XM_029339892.2 3050 2405 2392 3336 3205 Q5VYX0 2.19e-80 Renalase (EC 1.6.3.5) (Monoamine oxidase-C) (MAO-C) Homo sapiens (Human) negative regulation of blood pressure [GO:0045776]; negative regulation of heart rate [GO:0010459]; response to epinephrine [GO:0071871]; response to ischemia [GO:0002931]; response to salt [GO:1902074] GO:0002931; GO:0005576; GO:0005615; GO:0010459; GO:0016651; GO:0045776; GO:0051379; GO:0070404; GO:0071871; GO:0097621; GO:1902074 34181 XM_044316296.1 146 15 63 213 197 P18460 1.9e-46 Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (Tyrosine kinase receptor CEK2) Gallus gallus (Chicken) apoptotic process [GO:0006915]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0004714; GO:0005007; GO:0005524; GO:0005886; GO:0006915; GO:0007169; GO:0008284; GO:0017134; GO:0033674; GO:0043235; GO:0043410 34182 XM_044326885.1 49 45 77 133 0 NA NA NA NA NA NA 34183 XM_044318729.1 130 6 47 28 63 P35295 2.3e-36 Ras-related protein Rab-20 Mus musculus (Mouse) cellular response to type II interferon [GO:0071346]; intracellular protein transport [GO:0006886]; phagosome acidification [GO:0090383]; phagosome-lysosome fusion [GO:0090385] GO:0003924; GO:0005525; GO:0005794; GO:0006886; GO:0012505; GO:0030670; GO:0043231; GO:0045335; GO:0071346; GO:0090383; GO:0090385 34184 XM_044327036.1 8 0 7 13 12 NA NA NA NA NA NA 34185 XM_044315656.1 8 0 7 27 9 B3EWZ5 4.95e-36 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 34186 XM_044315656.1 8 0 7 27 9 B3EWZ5 9.53e-36 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 34187 XM_044315656.1 8 0 7 27 9 B3EWZ5 2.01e-33 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 34188 XM_044315656.1 8 0 7 27 9 B3EWZ5 2.71e-33 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 34189 XM_044315656.1 8 0 7 27 9 B3EWZ5 3.19e-33 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 34190 XM_044315656.1 8 0 7 27 9 B3EWZ5 7.97e-33 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 34191 XM_044315656.1 8 0 7 27 9 B3EWZ5 2.26e-31 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 34192 XM_044315656.1 8 0 7 27 9 B3EWZ5 7.74e-31 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 34193 XM_044315656.1 8 0 7 27 9 B3EWZ5 3.48e-30 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 34194 XM_044315656.1 8 0 7 27 9 B3EWZ5 5.85e-30 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 34195 XM_044315656.1 8 0 7 27 9 B3EWZ5 2.27e-29 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 34196 XM_044315656.1 8 0 7 27 9 B3EWZ5 2.73e-29 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 34197 XM_044315656.1 8 0 7 27 9 B3EWZ5 1.24e-28 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 34198 XM_044315656.1 8 0 7 27 9 B3EWZ5 3.27e-28 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 34199 XM_044315656.1 8 0 7 27 9 B3EWZ5 9.24e-28 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 34200 XM_044315656.1 8 0 7 27 9 B3EWZ5 9.61e-26 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 34201 XM_044315656.1 8 0 7 27 9 B3EWZ5 9.61e-26 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 34202 XM_044315656.1 8 0 7 27 9 B3EWZ5 9.7e-26 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 34203 XM_044315656.1 8 0 7 27 9 B3EWZ5 1.51e-25 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 34204 XM_044315656.1 8 0 7 27 9 B3EWZ5 2.96e-25 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 34205 XM_044315656.1 8 0 7 27 9 B3EWZ5 3.91e-25 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 34206 XM_044315656.1 8 0 7 27 9 B3EWZ5 7.23e-25 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 34207 XM_044315656.1 8 0 7 27 9 B3EWZ5 3.92e-24 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 34208 XM_044315147.1 6 0 0 2 9 NA NA NA NA NA NA 34209 XM_029340456.2 3149 2704 1633 3062 1499 NA NA NA NA NA NA 34210 XM_044316707.1 383 190 78 271 382 NA NA NA NA NA NA 34211 XM_029342457.2 275 307 202 329 313 Q1RMJ7 5.02e-72 tRNA selenocysteine 1-associated protein 1 (tRNA selenocysteine-associated protein 1) Bos taurus (Bovine) selenocysteine incorporation [GO:0001514] GO:0000049; GO:0001514; GO:0005634; GO:0005737 34212 XM_029339198.2 3658 2958 2575 6427 5065 Q6NT99 4.05e-28 Dual specificity protein phosphatase 23 (EC 3.1.3.16) (EC 3.1.3.48) (Low molecular mass dual specificity phosphatase 3) (LDP-3) Mus musculus (Mouse) dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470] GO:0004725; GO:0005654; GO:0005737; GO:0005829; GO:0006470; GO:0008138; GO:0016311; GO:0016791; GO:0017018 34213 XM_044307597.1 217 16 69 41 150 Q9LIQ4 2.38e-60 Hydroxyethylthiazole kinase (EC 2.7.1.50) (4-methyl-5-beta-hydroxyethylthiazole kinase) (TH kinase) (Thz kinase) Arabidopsis thaliana (Mouse-ear cress) phosphorylation [GO:0016310]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]; thiamine salvage [GO:0036172] GO:0000287; GO:0004417; GO:0005524; GO:0009228; GO:0009229; GO:0016310; GO:0036172 34214 XR_006391818.1 1 0 0 11 0 NA NA NA NA NA NA 34215 XM_044325219.1 17 52 0 86 135 P47972 2.1e-23 Neuronal pentraxin-2 (NP2) (Neuronal pentraxin II) (NP-II) Homo sapiens (Human) associative learning [GO:0008306]; chemical synaptic transmission [GO:0007268]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962] GO:0005576; GO:0007268; GO:0008306; GO:0030246; GO:0046872; GO:0098962; GO:0098978 34216 XM_029352498.2 7974 7264 4629 10064 7998 Q4GZT3 0 Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Transient receptor potential cation channel subfamily P member 2) Bos taurus (Bovine) calcium ion transmembrane transport [GO:0070588]; cell-cell signaling by wnt [GO:0198738]; cellular response to calcium ion [GO:0071277]; detection of mechanical stimulus [GO:0050982]; inorganic cation transmembrane transport [GO:0098662]; potassium ion transmembrane transport [GO:0071805]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]; regulation of ion transmembrane transport [GO:0034765]; release of sequestered calcium ion into cytosol [GO:0051209]; Wnt signaling pathway [GO:0016055] GO:0002133; GO:0005102; GO:0005245; GO:0005248; GO:0005261; GO:0005262; GO:0005267; GO:0005509; GO:0005783; GO:0005789; GO:0005794; GO:0005886; GO:0005929; GO:0015271; GO:0016020; GO:0016055; GO:0016323; GO:0030659; GO:0034703; GO:0034765; GO:0050982; GO:0051209; GO:0051262; GO:0051290; GO:0051371; GO:0060170; GO:0070588; GO:0071277; GO:0071805; GO:0098662; GO:0198738 34217 XM_029323498.2 0 0 0 16 0 NA NA NA NA NA NA 34218 XM_044323139.1 49 100 44 77 38 NA NA NA NA NA NA 34219 XM_044310968.1 0 0 0 9 0 NA NA NA NA NA NA 34220 XM_029355736.2 12 32 0 127 12 P24044 1.86e-47 Calmodulin Plasmodium falciparum NA GO:0005509; GO:0005737; GO:0020007 34221 XM_044319671.1 0 0 1 0 20 Q9CYL5 1.44e-27 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Mus musculus (Mouse) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070374 34222 XM_029347745.2 86 144 128 143 118 Q96DM1 1.42e-30 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 34223 XM_044319873.1 301 64 402 97 1033 NA NA NA NA NA NA 34224 XM_029329985.2 0 0 0 50 0 O46043 6.1e-39 Poly(ADP-ribose) glycohydrolase (EC 3.2.1.143) Drosophila melanogaster (Fruit fly) ATP generation from poly-ADP-D-ribose [GO:1990966]; Cajal body organization [GO:0030576]; carbohydrate metabolic process [GO:0005975]; female germ-line stem cell population maintenance [GO:0036099]; heterochromatin formation [GO:0031507]; maintenance of protein location in nucleus [GO:0051457]; nucleotide-sugar metabolic process [GO:0009225]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of RNA splicing [GO:0043484]; response to heat [GO:0009408] GO:0004649; GO:0005634; GO:0005654; GO:0005737; GO:0005975; GO:0006282; GO:0009225; GO:0009408; GO:0030576; GO:0031056; GO:0031507; GO:0036099; GO:0043484; GO:0051457; GO:1990966 34225 XM_044311392.1 111 18 185 59 422 P25931 1.45e-23 RYamide receptor (Neuropeptide Y-like receptor) (NPY-R) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218] GO:0001653; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0016020 34226 XM_029344148.2 440 0 49 362 425 Q54UT2 3.58e-62 Deoxyguanosine kinase (dGK) (EC 2.7.1.113) (DddGK) Dictyostelium discoideum (Social amoeba) deoxyguanosine salvage [GO:0006180]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; phosphorylation [GO:0016310] GO:0004138; GO:0005524; GO:0005737; GO:0005747; GO:0006120; GO:0006180; GO:0016310 34227 XM_044322093.1 61 3 7 2 1 NA NA NA NA NA NA 34228 XM_029324827.2 130 85 137 78 60 Q96PV6 7.6e-86 Leukocyte receptor cluster member 8 Homo sapiens (Human) NA GO:0005634; GO:0032991 34229 XR_006395715.1 0 0 0 12 2 NA NA NA NA NA NA 34230 XM_044320868.1 2876 3416 1370 2945 1481 NA NA NA NA NA NA 34231 XM_044326450.1 69 25 52 47 91 Q8IYQ7 0 Threonine synthase-like 1 (TSH1) Homo sapiens (Human) NA GO:0005737 34232 XM_044307736.1 92 379 473 691 447 Q96L93 0 Kinesin-like protein KIF16B (Sorting nexin-23) Homo sapiens (Human) early endosome to late endosome transport [GO:0045022]; endoderm development [GO:0007492]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; formation of primary germ layer [GO:0001704]; Golgi to endosome transport [GO:0006895]; microtubule-based movement [GO:0007018]; receptor catabolic process [GO:0032801]; regulation of receptor recycling [GO:0001919] GO:0001704; GO:0001919; GO:0003777; GO:0005524; GO:0005547; GO:0005737; GO:0005768; GO:0005769; GO:0005819; GO:0005829; GO:0005871; GO:0005874; GO:0006895; GO:0007018; GO:0007173; GO:0007492; GO:0008017; GO:0008543; GO:0008574; GO:0016887; GO:0031901; GO:0032266; GO:0032801; GO:0043325; GO:0045022; GO:0080025 34233 XM_044307736.1 92 379 473 691 447 Q96L93 5.89e-30 Kinesin-like protein KIF16B (Sorting nexin-23) Homo sapiens (Human) early endosome to late endosome transport [GO:0045022]; endoderm development [GO:0007492]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; formation of primary germ layer [GO:0001704]; Golgi to endosome transport [GO:0006895]; microtubule-based movement [GO:0007018]; receptor catabolic process [GO:0032801]; regulation of receptor recycling [GO:0001919] GO:0001704; GO:0001919; GO:0003777; GO:0005524; GO:0005547; GO:0005737; GO:0005768; GO:0005769; GO:0005819; GO:0005829; GO:0005871; GO:0005874; GO:0006895; GO:0007018; GO:0007173; GO:0007492; GO:0008017; GO:0008543; GO:0008574; GO:0016887; GO:0031901; GO:0032266; GO:0032801; GO:0043325; GO:0045022; GO:0080025 34234 XM_029330175.2 1127 593 2583 1845 1569 A4UTP7 2.73e-63 Myocyte-specific enhancer factor 2C Sus scrofa (Pig) B cell homeostasis [GO:0001782]; B cell proliferation [GO:0042100]; B cell receptor signaling pathway [GO:0050853]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cardiac ventricle formation [GO:0003211]; cardiocyte differentiation [GO:0035051]; cellular response to calcium ion [GO:0071277]; cellular response to fluid shear stress [GO:0071498]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cellular response to trichostatin A [GO:0035984]; cellular response to xenobiotic stimulus [GO:0071466]; chondrocyte differentiation [GO:0002062]; endochondral ossification [GO:0001958]; epithelial cell proliferation involved in renal tubule morphogenesis [GO:2001013]; germinal center formation [GO:0002467]; glomerulus morphogenesis [GO:0072102]; heart development [GO:0007507]; heart looping [GO:0001947]; humoral immune response [GO:0006959]; learning or memory [GO:0007611]; MAPK cascade [GO:0000165]; melanocyte differentiation [GO:0030318]; muscle cell fate determination [GO:0007521]; negative regulation of gene expression [GO:0010629]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of ossification [GO:0030279]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nephron tubule epithelial cell differentiation [GO:0072160]; neural crest cell differentiation [GO:0014033]; neuron development [GO:0048666]; neuron differentiation [GO:0030182]; osteoblast differentiation [GO:0001649]; outflow tract morphogenesis [GO:0003151]; platelet formation [GO:0030220]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of behavioral fear response [GO:2000987]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cardiac muscle cell differentiation [GO:2000727]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of macrophage apoptotic process [GO:2000111]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of skeletal muscle cell differentiation [GO:2001016]; positive regulation of skeletal muscle tissue development [GO:0048643]; positive regulation of transcription by RNA polymerase II [GO:0045944]; primary heart field specification [GO:0003138]; regulation of germinal center formation [GO:0002634]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of synaptic activity [GO:0060025]; regulation of transcription by RNA polymerase II [GO:0006357]; renal tubule morphogenesis [GO:0061333]; secondary heart field specification [GO:0003139]; sinoatrial valve morphogenesis [GO:0003185]; skeletal muscle tissue development [GO:0007519]; smooth muscle cell differentiation [GO:0051145]; ventricular cardiac muscle cell differentiation [GO:0055012] GO:0000122; GO:0000165; GO:0000976; GO:0000977; GO:0000978; GO:0000981; GO:0001228; GO:0001568; GO:0001649; GO:0001782; GO:0001947; GO:0001958; GO:0001974; GO:0002062; GO:0002467; GO:0002634; GO:0003138; GO:0003139; GO:0003151; GO:0003185; GO:0003211; GO:0003677; GO:0003700; GO:0005634; GO:0005737; GO:0006357; GO:0006959; GO:0007507; GO:0007519; GO:0007521; GO:0007611; GO:0010628; GO:0010629; GO:0010694; GO:0014033; GO:0016528; GO:0016607; GO:0030182; GO:0030220; GO:0030279; GO:0030318; GO:0030501; GO:0030890; GO:0032991; GO:0035051; GO:0035984; GO:0042100; GO:0043524; GO:0045652; GO:0045663; GO:0045666; GO:0045669; GO:0045893; GO:0045944; GO:0046983; GO:0048643; GO:0048666; GO:0050853; GO:0051145; GO:0055012; GO:0060025; GO:0060045; GO:0061333; GO:0071222; GO:0071277; GO:0071374; GO:0071466; GO:0071498; GO:0071560; GO:0072102; GO:0072160; GO:2000111; GO:2000727; GO:2000987; GO:2001013; GO:2001016 34235 XM_044317952.1 0 0 19 0 0 Q9FT73 1.5e-23 ATP-dependent DNA helicase Q-like 2 (EC 3.6.4.12) (RecQ-like protein 2) (AtRQ2) (AtRecQ2) (AtRecQl2) Arabidopsis thaliana (Mouse-ear cress) DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724] GO:0000724; GO:0003677; GO:0005524; GO:0005694; GO:0005737; GO:0006268; GO:0006281; GO:0006310; GO:0009378; GO:0016592; GO:0016887; GO:0032508; GO:0043138; GO:0046872 34236 XM_029354398.2 2 84 300 172 136 NA NA NA NA NA NA 34237 XM_029342158.2 103 25 24 44 115 NA NA NA NA NA NA 34238 XM_029354458.2 1164 2045 697 1642 1468 Q5XGA9 7.69e-90 N-alpha-acetyltransferase 50 (EC 2.3.1.258) (N-acetyltransferase NAT13) (N-epsilon-acetyltransferase 50) (EC 2.3.1.-) (NatE catalytic subunit) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) establishment of mitotic sister chromatid cohesion [GO:0034087]; mitotic sister chromatid cohesion, centromeric [GO:0071962]; N-terminal protein amino acid acetylation [GO:0006474] GO:0004596; GO:0005634; GO:0005737; GO:0005829; GO:0006474; GO:0010485; GO:0034087; GO:0052858; GO:0071962 34239 XM_029342160.2 71 132 65 87 58 NA NA NA NA NA NA 34240 XM_029348721.2 44 164 126 73 0 NA NA NA NA NA NA 34241 XM_029356834.2 3 0 1 6 16 NA NA NA NA NA NA 34242 XM_029332630.2 339 127 228 208 364 Q12888 2.99e-37 TP53-binding protein 1 (53BP1) (p53-binding protein 1) (p53BP1) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; cellular response to X-ray [GO:0071481]; DNA damage checkpoint signaling [GO:0000077]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of isotype switching [GO:0045830]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein homooligomerization [GO:0051260] GO:0000077; GO:0000776; GO:0000781; GO:0002039; GO:0003684; GO:0003712; GO:0005634; GO:0005654; GO:0005657; GO:0005737; GO:0006303; GO:0006974; GO:0016604; GO:0035064; GO:0035861; GO:0042162; GO:0042393; GO:0045830; GO:0045893; GO:0045944; GO:0051091; GO:0051260; GO:0061629; GO:0061649; GO:0071481; GO:1990391; GO:2000042 34243 XM_044306940.1 9 59 214 3 22 O18806 2e-40 Coagulation factor VIII (Procoagulant component) Canis lupus familiaris (Dog) (Canis familiaris) acute-phase response [GO:0006953]; blood coagulation [GO:0007596] GO:0005507; GO:0005615; GO:0006953; GO:0007596; GO:0016491 34244 XM_029335202.2 5738 8429 5909 5315 4376 Q5FVL2 3.41e-43 ER membrane protein complex subunit 8 (Neighbor of COX4) Rattus norvegicus (Rat) protein insertion into ER membrane by stop-transfer membrane-anchor sequence [GO:0045050]; tail-anchored membrane protein insertion into ER membrane [GO:0071816] GO:0005737; GO:0005794; GO:0032977; GO:0045050; GO:0071816; GO:0072546 34245 XM_029340857.2 461 99 66 433 156 A7S2N8 0 E3 UFM1-protein ligase 1 homolog (EC 2.3.2.-) (E3 UFM1-protein transferase 1 homolog) Nematostella vectensis (Starlet sea anemone) protein K69-linked ufmylation [GO:1990592]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]; response to endoplasmic reticulum stress [GO:0034976] GO:0005789; GO:0032434; GO:0034976; GO:0061666; GO:0071568; GO:1990592 34246 XM_029350705.2 476 568 549 860 714 NA NA NA NA NA NA 34247 XM_044319267.1 23 0 0 0 70 NA NA NA NA NA NA 34248 XM_029338936.2 73 0 35 14 104 NA NA NA NA NA NA 34249 XR_003824893.2 47 19 8 73 59 NA NA NA NA NA NA 34250 XM_029347882.2 715 1456 573 720 386 NA NA NA NA NA NA 34251 XM_029336980.2 386 553 602 1085 1030 NA NA NA NA NA NA 34252 XM_044311921.1 259 50 231 51 464 NA NA NA NA NA NA 34253 XR_003824782.2 84 157 28 160 46 NA NA NA NA NA NA 34254 XR_006392999.1 41 2 25 5 151 NA NA NA NA NA NA 34255 XM_044328896.1 27 4 68 3 61 NA NA NA NA NA NA 34256 XM_029337250.2 1284 798 1071 1098 1547 Q9NXZ2 0 Probable ATP-dependent RNA helicase DDX43 (EC 3.6.4.13) (Cancer/testis antigen 13) (CT13) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen) Homo sapiens (Human) NA GO:0003723; GO:0003724; GO:0005524; GO:0016887 34257 XM_044320854.1 11 5 4 54 51 NA NA NA NA NA NA 34258 XM_029341272.2 0 45 0 0 105 Q7RTR2 2.15e-39 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 34259 XM_029341272.2 0 45 0 0 105 Q7RTR2 1.35e-38 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 34260 XM_029341272.2 0 45 0 0 105 Q7RTR2 2.5e-34 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 34261 XM_029341272.2 0 45 0 0 105 Q7RTR2 5.86e-28 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 34262 XM_044314758.1 34 44 36 15 8 Q9UBN7 4.79e-40 Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-) Homo sapiens (Human) aggresome assembly [GO:0070842]; autophagy [GO:0006914]; axonal transport of mitochondrion [GO:0019896]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to misfolded protein [GO:0071218]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to topologically incorrect protein [GO:0035967]; cilium assembly [GO:0060271]; cilium disassembly [GO:0061523]; collateral sprouting [GO:0048668]; dendritic spine morphogenesis [GO:0060997]; epigenetic regulation of gene expression [GO:0040029]; histone deacetylation [GO:0016575]; Hsp90 deacetylation [GO:0070846]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of protein-containing complex disassembly [GO:0043242]; negative regulation of proteolysis [GO:0045861]; negative regulation of transcription by RNA polymerase II [GO:0000122]; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:0061734]; peptidyl-lysine deacetylation [GO:0034983]; polyubiquitinated misfolded protein transport [GO:0070845]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of hydrogen peroxide-mediated programmed cell death [GO:1901300]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of tubulin deacetylation [GO:0090044]; protein deacetylation [GO:0006476]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; protein-containing complex disassembly [GO:0032984]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of autophagy [GO:0010506]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of establishment of protein localization [GO:0070201]; regulation of fat cell differentiation [GO:0045598]; regulation of macroautophagy [GO:0016241]; regulation of microtubule-based movement [GO:0060632]; regulation of protein stability [GO:0031647]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]; response to dexamethasone [GO:0071548]; response to growth factor [GO:0070848]; response to immobilization stress [GO:0035902]; response to misfolded protein [GO:0051788]; tubulin deacetylation [GO:0090042]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] GO:0000118; GO:0000122; GO:0000209; GO:0000978; GO:0001222; GO:0001975; GO:0003779; GO:0004407; GO:0005634; GO:0005654; GO:0005737; GO:0005771; GO:0005813; GO:0005829; GO:0005874; GO:0005875; GO:0005901; GO:0006476; GO:0006515; GO:0006886; GO:0006914; GO:0007026; GO:0008013; GO:0008017; GO:0008270; GO:0010506; GO:0010634; GO:0010727; GO:0016234; GO:0016235; GO:0016241; GO:0016575; GO:0019896; GO:0019899; GO:0030424; GO:0030425; GO:0031252; GO:0031333; GO:0031593; GO:0031625; GO:0031647; GO:0031648; GO:0032418; GO:0032984; GO:0033138; GO:0033558; GO:0034983; GO:0035902; GO:0035967; GO:0036064; GO:0040029; GO:0042826; GO:0042903; GO:0043014; GO:0043130; GO:0043162; GO:0043204; GO:0043242; GO:0045598; GO:0045861; GO:0045892; GO:0048156; GO:0048471; GO:0048487; GO:0048668; GO:0048843; GO:0050775; GO:0051354; GO:0051412; GO:0051787; GO:0051788; GO:0051879; GO:0051968; GO:0060271; GO:0060632; GO:0060765; GO:0060997; GO:0061523; GO:0061734; GO:0070201; GO:0070301; GO:0070840; GO:0070842; GO:0070845; GO:0070846; GO:0070848; GO:0071218; GO:0071374; GO:0071548; GO:0090042; GO:0090044; GO:1901300; GO:1901984; GO:1903146; GO:1903223; GO:1904056; GO:1904115; GO:2000273 34263 XM_044314758.1 34 44 36 15 8 Q9UBN7 1.14e-33 Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-) Homo sapiens (Human) aggresome assembly [GO:0070842]; autophagy [GO:0006914]; axonal transport of mitochondrion [GO:0019896]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to misfolded protein [GO:0071218]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to topologically incorrect protein [GO:0035967]; cilium assembly [GO:0060271]; cilium disassembly [GO:0061523]; collateral sprouting [GO:0048668]; dendritic spine morphogenesis [GO:0060997]; epigenetic regulation of gene expression [GO:0040029]; histone deacetylation [GO:0016575]; Hsp90 deacetylation [GO:0070846]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of protein-containing complex disassembly [GO:0043242]; negative regulation of proteolysis [GO:0045861]; negative regulation of transcription by RNA polymerase II [GO:0000122]; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:0061734]; peptidyl-lysine deacetylation [GO:0034983]; polyubiquitinated misfolded protein transport [GO:0070845]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of hydrogen peroxide-mediated programmed cell death [GO:1901300]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of tubulin deacetylation [GO:0090044]; protein deacetylation [GO:0006476]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; protein-containing complex disassembly [GO:0032984]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of autophagy [GO:0010506]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of establishment of protein localization [GO:0070201]; regulation of fat cell differentiation [GO:0045598]; regulation of macroautophagy [GO:0016241]; regulation of microtubule-based movement [GO:0060632]; regulation of protein stability [GO:0031647]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]; response to dexamethasone [GO:0071548]; response to growth factor [GO:0070848]; response to immobilization stress [GO:0035902]; response to misfolded protein [GO:0051788]; tubulin deacetylation [GO:0090042]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] GO:0000118; GO:0000122; GO:0000209; GO:0000978; GO:0001222; GO:0001975; GO:0003779; GO:0004407; GO:0005634; GO:0005654; GO:0005737; GO:0005771; GO:0005813; GO:0005829; GO:0005874; GO:0005875; GO:0005901; GO:0006476; GO:0006515; GO:0006886; GO:0006914; GO:0007026; GO:0008013; GO:0008017; GO:0008270; GO:0010506; GO:0010634; GO:0010727; GO:0016234; GO:0016235; GO:0016241; GO:0016575; GO:0019896; GO:0019899; GO:0030424; GO:0030425; GO:0031252; GO:0031333; GO:0031593; GO:0031625; GO:0031647; GO:0031648; GO:0032418; GO:0032984; GO:0033138; GO:0033558; GO:0034983; GO:0035902; GO:0035967; GO:0036064; GO:0040029; GO:0042826; GO:0042903; GO:0043014; GO:0043130; GO:0043162; GO:0043204; GO:0043242; GO:0045598; GO:0045861; GO:0045892; GO:0048156; GO:0048471; GO:0048487; GO:0048668; GO:0048843; GO:0050775; GO:0051354; GO:0051412; GO:0051787; GO:0051788; GO:0051879; GO:0051968; GO:0060271; GO:0060632; GO:0060765; GO:0060997; GO:0061523; GO:0061734; GO:0070201; GO:0070301; GO:0070840; GO:0070842; GO:0070845; GO:0070846; GO:0070848; GO:0071218; GO:0071374; GO:0071548; GO:0090042; GO:0090044; GO:1901300; GO:1901984; GO:1903146; GO:1903223; GO:1904056; GO:1904115; GO:2000273 34264 XM_044329101.1 536 179 155 424 283 Q86YS7 1.78e-170 C2 domain-containing protein 5 (C2 domain-containing phosphoprotein of 138 kDa) Homo sapiens (Human) cellular response to insulin stimulus [GO:0032869]; insulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028]; intracellular protein transmembrane transport [GO:0065002]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of vesicle fusion [GO:0031340]; protein localization to plasma membrane [GO:0072659] GO:0005509; GO:0005544; GO:0005829; GO:0005886; GO:0005938; GO:0010828; GO:0030659; GO:0031340; GO:0032587; GO:0032869; GO:0034451; GO:0038028; GO:0065002; GO:0072659; GO:0090314 34265 XM_044329101.1 536 179 155 424 283 Q86YS7 5.08e-105 C2 domain-containing protein 5 (C2 domain-containing phosphoprotein of 138 kDa) Homo sapiens (Human) cellular response to insulin stimulus [GO:0032869]; insulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028]; intracellular protein transmembrane transport [GO:0065002]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of vesicle fusion [GO:0031340]; protein localization to plasma membrane [GO:0072659] GO:0005509; GO:0005544; GO:0005829; GO:0005886; GO:0005938; GO:0010828; GO:0030659; GO:0031340; GO:0032587; GO:0032869; GO:0034451; GO:0038028; GO:0065002; GO:0072659; GO:0090314 34266 XM_029339719.2 0 1 1 250 559 Q7Z7A1 4.98e-79 Centriolin (Centrosomal protein 1) (Centrosomal protein of 110 kDa) (Cep110) Homo sapiens (Human) aorta development [GO:0035904]; cell cycle [GO:0007049]; cell division [GO:0051301]; coronary vasculature development [GO:0060976]; kidney development [GO:0001822]; ventricular septum development [GO:0003281] GO:0001822; GO:0003281; GO:0005813; GO:0005815; GO:0005829; GO:0007049; GO:0016020; GO:0034451; GO:0035904; GO:0048471; GO:0051301; GO:0060976; GO:0090543; GO:0090619; GO:0097431; GO:0120103 34267 XR_006395887.1 0 0 0 26 0 Q8WZA2 0 Rap guanine nucleotide exchange factor 4 (Exchange factor directly activated by cAMP 2) (Exchange protein directly activated by cAMP 2) (EPAC 2) (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) Homo sapiens (Human) adaptive immune response [GO:0002250]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; calcium-ion regulated exocytosis [GO:0017156]; G protein-coupled receptor signaling pathway [GO:0007186]; insulin secretion [GO:0030073]; positive regulation of GTPase activity [GO:0043547]; positive regulation of insulin secretion [GO:0032024]; Ras protein signal transduction [GO:0007265]; regulation of exocytosis [GO:0017157]; regulation of synaptic vesicle cycle [GO:0098693] GO:0002250; GO:0005085; GO:0005096; GO:0005829; GO:0005886; GO:0007186; GO:0007189; GO:0007265; GO:0016020; GO:0017156; GO:0017157; GO:0030073; GO:0030552; GO:0030674; GO:0031267; GO:0032024; GO:0043547; GO:0098686; GO:0098693 34268 XM_044323243.1 211 188 125 290 385 Q9NWU1 1.11e-129 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial (EC 2.3.1.41) (Beta-ketoacyl-ACP synthase) Homo sapiens (Human) acyl-CoA metabolic process [GO:0006637]; fatty acid biosynthetic process [GO:0006633]; medium-chain fatty acid biosynthetic process [GO:0051792]; short-chain fatty acid biosynthetic process [GO:0051790] GO:0004315; GO:0005739; GO:0005829; GO:0006633; GO:0006637; GO:0051790; GO:0051792 34269 XM_029325341.2 785 456 428 1115 1106 NA NA NA NA NA NA 34270 XM_029333707.2 2107 2100 1392 3040 2211 Q60553 2.89e-53 Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (p185erbB2) (CD antigen CD340) Mesocricetus auratus (Golden hamster) cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; central nervous system development [GO:0007417]; ERBB signaling pathway [GO:0038127]; intracellular signal transduction [GO:0035556]; positive regulation of cell growth [GO:0030307]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; regulation of cell population proliferation [GO:0042127]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886] GO:0001042; GO:0004714; GO:0005524; GO:0005634; GO:0005769; GO:0005886; GO:0007417; GO:0030307; GO:0032587; GO:0032886; GO:0035556; GO:0038127; GO:0042127; GO:0045727; GO:0045943; GO:0048471; GO:0070372; GO:0071363; GO:0071364; GO:0090314 34271 XR_006393852.1 10 1 3 0 27 NA NA NA NA NA NA 34272 XM_044328397.1 0 17 5 17 44 NA NA NA NA NA NA 34273 XM_044315437.1 31 74 5062 72 161 NA NA NA NA NA NA 34274 XM_044319048.1 115 44 47 50 63 NA NA NA NA NA NA 34275 XR_006391287.1 6 4 5 3 9 NA NA NA NA NA NA 34276 XM_044309635.1 10698 11063 4989 4203 4008 NA NA NA NA NA NA 34277 XR_003826856.2 348 264 168 308 235 NA NA NA NA NA NA 34278 XM_044310805.1 52 52 15 28 35 Q80XJ3 2.07e-69 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 34279 XM_044310805.1 52 52 15 28 35 Q80XJ3 1.44e-62 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 34280 XM_044310805.1 52 52 15 28 35 Q80XJ3 1.5e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 34281 XM_044310805.1 52 52 15 28 35 Q80XJ3 1.66e-55 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 34282 XM_044310805.1 52 52 15 28 35 Q80XJ3 2.7e-51 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 34283 XM_044310805.1 52 52 15 28 35 Q80XJ3 4.04e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 34284 XM_044320223.1 275 82 93 1854 415 NA NA NA NA NA NA 34285 XM_044320635.1 11 47 0 0 0 NA NA NA NA NA NA 34286 XM_029329667.2 429 188 226 292 512 Q6INP8 6.63e-71 Mediator of RNA polymerase II transcription subunit 1 (Mediator complex subunit 1) Xenopus laevis (African clawed frog) positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0003712; GO:0016592; GO:0045944 34287 XM_029342647.2 2559 2196 1460 2016 1770 Q66I24 0 Argininosuccinate synthase (EC 6.3.4.5) (Citrulline--aspartate ligase) Danio rerio (Zebrafish) (Brachydanio rerio) arginine biosynthetic process [GO:0006526]; argininosuccinate metabolic process [GO:0000053]; urea cycle [GO:0000050] GO:0000050; GO:0000053; GO:0004055; GO:0005524; GO:0005737; GO:0005829; GO:0006526 34288 XM_044325087.1 7 0 0 0 0 NA NA NA NA NA NA 34289 XM_029343992.2 663 584 405 424 333 NA NA NA NA NA NA 34290 XR_003824477.2 33 34 22 18 14 NA NA NA NA NA NA 34291 XM_044310973.1 56 13 12 11 91 NA NA NA NA NA NA 34292 XM_044311457.1 48 21 83 57 117 Q9UKP5 1.93e-113 A disintegrin and metalloproteinase with thrombospondin motifs 6 (ADAM-TS 6) (ADAM-TS6) (ADAMTS-6) (EC 3.4.24.-) Homo sapiens (Human) aorta development [GO:0035904]; cardiac septum development [GO:0003279]; coronary vasculature development [GO:0060976]; extracellular matrix organization [GO:0030198]; kidney development [GO:0001822]; proteolysis [GO:0006508] GO:0001822; GO:0003279; GO:0004222; GO:0005576; GO:0006508; GO:0008237; GO:0030198; GO:0031012; GO:0035904; GO:0046872; GO:0060976 34293 XM_044323664.1 0 36 0 34 65 Q9DEY9 2.7e-73 RecQ-like DNA helicase BLM (EC 3.6.4.12) (Bloom syndrome protein homolog) (xBLM) (RecQ helicase homolog) Xenopus laevis (African clawed frog) DNA double-strand break processing [GO:0000729]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA replication [GO:0006260]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of DNA-templated DNA replication [GO:0090329] GO:0000400; GO:0000729; GO:0003677; GO:0003678; GO:0003697; GO:0005524; GO:0005634; GO:0006260; GO:0006310; GO:0008094; GO:0008270; GO:0009378; GO:0016887; GO:0032508; GO:0042803; GO:0043138; GO:0051259; GO:0051260; GO:0061749; GO:0090329 34294 XM_029344599.2 252 104 159 160 74 A1DWM3 1.98e-29 Major facilitator superfamily domain-containing protein 6 (Macrophage MHC class I receptor 2 homolog) Sus scrofa (Pig) antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590] GO:0005886; GO:0016020; GO:0042590 34295 XM_044323274.1 3 0 3 11 6 Q9VBW3 1.3e-59 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 34296 XM_044326100.1 16 139 20 13 106 NA NA NA NA NA NA 34297 XM_044310631.1 7679 12082 10607 14571 8393 NA NA NA NA NA NA 34298 XM_029345605.2 1710 1494 1153 1377 872 O14662 1.22e-86 Syntaxin-16 (Syn16) Homo sapiens (Human) endocytic recycling [GO:0032456]; intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]; vesicle docking [GO:0048278]; vesicle fusion [GO:0006906] GO:0000139; GO:0000149; GO:0005484; GO:0005737; GO:0005794; GO:0005802; GO:0005829; GO:0005925; GO:0006886; GO:0006906; GO:0012505; GO:0016020; GO:0019905; GO:0030672; GO:0031201; GO:0031985; GO:0032456; GO:0032588; GO:0042147; GO:0043231; GO:0048278; GO:0048471 34299 XM_029339217.2 2541 1500 1217 2859 2868 Q5RDQ2 6.16e-164 Protein PALS1 (MAGUK p55 subfamily member 5) (Protein associated with Lin-7 1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) central nervous system neuron development [GO:0021954]; cerebral cortex development [GO:0021987]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015] GO:0005524; GO:0005794; GO:0005912; GO:0005923; GO:0016324; GO:0017015; GO:0021954; GO:0021987; GO:0030424; GO:0043204 34300 XM_029338646.2 10 5 0 6 38 NA NA NA NA NA NA 34301 XR_006392866.1 27 0 23 6 103 NA NA NA NA NA NA 34302 XR_006393451.1 35 45 54 93 81 NA NA NA NA NA NA 34303 XM_044318254.1 398 191 127 103 63 NA NA NA NA NA NA 34304 XM_044319708.1 106 25 0 0 0 Q54H46 1.54e-24 Probable serine/threonine-protein kinase drkA (EC 2.7.11.1) (Receptor-like kinase 1) (Receptor-like kinase A) (Vesicle-associated receptor tyrosine kinase-like protein 1) Dictyostelium discoideum (Social amoeba) receptor signaling pathway via STAT [GO:0097696]; signal transduction [GO:0007165] GO:0004672; GO:0004674; GO:0004713; GO:0005524; GO:0005737; GO:0007165; GO:0016020; GO:0097677; GO:0097696; GO:0106310 34305 XM_044319634.1 18 3 2 26 17 NA NA NA NA NA NA 34306 XM_044328792.1 12 0 11 0 0 E9Q236 0 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 34307 XM_029328576.2 6 0 0 0 4 Q5U374 9.35e-120 Kelch-like protein 12 Danio rerio (Zebrafish) (Brachydanio rerio) anterior/posterior pattern specification [GO:0009952]; convergent extension involved in axis elongation [GO:0060028]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; protein monoubiquitination [GO:0006513]; Wnt signaling pathway [GO:0016055] GO:0006513; GO:0006888; GO:0009952; GO:0014029; GO:0014032; GO:0016055; GO:0030127; GO:0030134; GO:0031463; GO:0048208; GO:0060028 34308 XM_029336647.2 1261 573 702 757 305 Q53HC0 7.69e-23 Coiled-coil domain-containing protein 92 (Limkain beta-2) Homo sapiens (Human) innate immune response [GO:0045087]; regulation of defense response to virus [GO:0050688] GO:0005654; GO:0005737; GO:0005813; GO:0005814; GO:0042802; GO:0043231; GO:0045087; GO:0050688 34309 XM_029328313.2 0 0 0 0 6 Q9M2U3 2.61e-24 Protein ALP1-like (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) NA GO:0000118; GO:0004518; GO:0046872 34310 XM_044322256.1 0 0 0 12 6 NA NA NA NA NA NA 34311 XM_029356266.2 157 226 132 124 485 Q95108 1.04e-35 Thioredoxin, mitochondrial (MTRX) (Mt-Trx) (Thioredoxin-2) Bos taurus (Bovine) cell redox homeostasis [GO:0045454] GO:0005730; GO:0005739; GO:0015035; GO:0045454 34312 XM_029344727.2 0 0 0 0 962 Q5R2J4 7.02e-76 Protein APCDD1 (Adenomatosis polyposis coli down-regulated 1 protein homolog) (PsAPCDD1) Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis) negative regulation of Wnt signaling pathway [GO:0030178]; Wnt signaling pathway [GO:0016055] GO:0005615; GO:0005886; GO:0016055; GO:0017147; GO:0030178 34313 XR_003825009.2 32 3 27 7 76 NA NA NA NA NA NA 34314 XM_029342135.2 646 249 389 578 583 NA NA NA NA NA NA 34315 XM_044314460.1 0 230 0 0 1 NA NA NA NA NA NA 34316 XM_029352446.2 18 11 34 36 166 NA NA NA NA NA NA 34317 XM_029350436.2 1315 1184 678 963 866 NA NA NA NA NA NA 34318 XM_044310448.1 32 40 94 40 49 NA NA NA NA NA NA 34319 XM_044307767.1 907 313 57 416 0 P14543 1.66e-87 Nidogen-1 (NID-1) (Entactin) Homo sapiens (Human) basement membrane organization [GO:0071711]; cell-matrix adhesion [GO:0007160]; glomerular basement membrane development [GO:0032836]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of muscle cell differentiation [GO:0051149]; regulation of basement membrane organization [GO:0110011] GO:0005201; GO:0005509; GO:0005518; GO:0005576; GO:0005604; GO:0005886; GO:0007160; GO:0010811; GO:0032836; GO:0043236; GO:0043237; GO:0043394; GO:0045785; GO:0051149; GO:0062023; GO:0070062; GO:0071711; GO:0098637; GO:0110011; GO:2001046 34320 XM_044307767.1 907 313 57 416 0 P14543 3.51e-43 Nidogen-1 (NID-1) (Entactin) Homo sapiens (Human) basement membrane organization [GO:0071711]; cell-matrix adhesion [GO:0007160]; glomerular basement membrane development [GO:0032836]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of muscle cell differentiation [GO:0051149]; regulation of basement membrane organization [GO:0110011] GO:0005201; GO:0005509; GO:0005518; GO:0005576; GO:0005604; GO:0005886; GO:0007160; GO:0010811; GO:0032836; GO:0043236; GO:0043237; GO:0043394; GO:0045785; GO:0051149; GO:0062023; GO:0070062; GO:0071711; GO:0098637; GO:0110011; GO:2001046 34321 XM_044307767.1 907 313 57 416 0 P14543 4.01e-22 Nidogen-1 (NID-1) (Entactin) Homo sapiens (Human) basement membrane organization [GO:0071711]; cell-matrix adhesion [GO:0007160]; glomerular basement membrane development [GO:0032836]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of muscle cell differentiation [GO:0051149]; regulation of basement membrane organization [GO:0110011] GO:0005201; GO:0005509; GO:0005518; GO:0005576; GO:0005604; GO:0005886; GO:0007160; GO:0010811; GO:0032836; GO:0043236; GO:0043237; GO:0043394; GO:0045785; GO:0051149; GO:0062023; GO:0070062; GO:0071711; GO:0098637; GO:0110011; GO:2001046 34322 XM_044310320.1 44 17 10 9 63 Q80XJ3 1.76e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 34323 XR_003828648.2 124 27 26 57 105 NA NA NA NA NA NA 34324 XM_044318483.1 0 11 0 0 0 NA NA NA NA NA NA 34325 XM_044309825.1 30 29 22 53 20 NA NA NA NA NA NA 34326 XM_029333562.2 89 2 19 18 42 P25228 1e-68 Ras-related protein Rab-3 Drosophila melanogaster (Fruit fly) cytoskeletal matrix organization at active zone [GO:0048789]; maintenance of presynaptic active zone structure [GO:0048790]; neurotransmitter secretion [GO:0007269]; protein localization to plasma membrane [GO:0072659]; protein secretion [GO:0009306]; Rab protein signal transduction [GO:0032482]; regulation of exocytosis [GO:0017157]; regulation of neurotransmitter secretion [GO:0046928]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic vesicle fusion to presynaptic active zone membrane [GO:0031630]; vesicle docking involved in exocytosis [GO:0006904]; vesicle-mediated transport [GO:0016192]; viral entry into host cell [GO:0046718] GO:0003924; GO:0005525; GO:0005768; GO:0005886; GO:0006904; GO:0007269; GO:0008021; GO:0009306; GO:0016192; GO:0017157; GO:0031489; GO:0031630; GO:0031982; GO:0032482; GO:0043231; GO:0045202; GO:0046718; GO:0046928; GO:0048172; GO:0048786; GO:0048789; GO:0048790; GO:0072659 34327 XR_006395760.1 18 3 7 6 4 NA NA NA NA NA NA 34328 XM_029335885.2 25621 41955 22526 42445 24344 NA NA NA NA NA NA 34329 XM_029350296.2 185 42 359 264 185 D3YXG0 7.64e-31 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 34330 XM_029350296.2 185 42 359 264 185 D3YXG0 3.67e-28 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 34331 XM_029350296.2 185 42 359 264 185 D3YXG0 7.49e-27 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 34332 XM_029350296.2 185 42 359 264 185 D3YXG0 1.8e-23 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 34333 XM_029350296.2 185 42 359 264 185 D3YXG0 4.75e-23 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 34334 XM_029350296.2 185 42 359 264 185 D3YXG0 8.17e-23 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 34335 XM_029350296.2 185 42 359 264 185 D3YXG0 2.13e-22 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 34336 XM_029350296.2 185 42 359 264 185 D3YXG0 2.17e-22 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 34337 XM_029350296.2 185 42 359 264 185 D3YXG0 6.65e-22 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 34338 XM_029350296.2 185 42 359 264 185 D3YXG0 3.01e-21 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 34339 XM_029350296.2 185 42 359 264 185 D3YXG0 4.3e-21 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 34340 XM_029350296.2 185 42 359 264 185 D3YXG0 8.32e-21 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 34341 XM_044309234.1 82 26 8 36 72 C3ZQF9 1.72e-24 QRFP-like peptide receptor Branchiostoma floridae (Florida lancelet) (Amphioxus) cellular response to peptide [GO:1901653]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:1901653 34342 XM_044320023.1 106 22 5 42 44 NA NA NA NA NA NA 34343 XM_029342501.2 48 27 18 21 46 NA NA NA NA NA NA 34344 XM_029335913.2 737 737 595 651 619 Q5M9P8 3.49e-91 ADP-ribosylation factor-like protein 6 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; determination of left/right symmetry [GO:0007368]; gastrulation [GO:0007369]; intracellular protein transport [GO:0006886]; Kupffer's vesicle development [GO:0070121]; melanosome transport [GO:0032402]; pectoral fin development [GO:0033339]; protein localization to cilium [GO:0061512]; regulation of Notch signaling pathway [GO:0008593]; response to stimulus [GO:0050896]; vesicle-mediated transport [GO:0016192]; visual perception [GO:0007601] GO:0003924; GO:0005525; GO:0005737; GO:0005930; GO:0006886; GO:0007368; GO:0007369; GO:0007601; GO:0008593; GO:0016192; GO:0032402; GO:0033339; GO:0046872; GO:0050896; GO:0060170; GO:0060271; GO:0061512; GO:0070121 34345 XM_044327855.1 21 18 21 34 73 NA NA NA NA NA NA 34346 XM_029356346.2 1003 2 957 1636 1286 Q8CIQ7 0 Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP) Mus musculus (Mouse) small GTPase mediated signal transduction [GO:0007264] GO:0005085; GO:0005096; GO:0005737; GO:0005829; GO:0005886; GO:0007264; GO:0017124; GO:0031267 34347 XM_029328222.2 12 16 23 62 81 NA NA NA NA NA NA 34348 XM_029343214.2 0 43 0 164 247 Q41745 1.12e-74 1-acyl-sn-glycerol-3-phosphate acyltransferase PLS1 (EC 2.3.1.51) (Phospholipid synthesis protein 1) Zea mays (Maize) CDP-diacylglycerol biosynthetic process [GO:0016024] GO:0003841; GO:0012505; GO:0016020; GO:0016024; GO:0016746 34349 XM_044308951.1 43 19 0 71 5 NA NA NA NA NA NA 34350 XM_029326875.2 44 37 131 0 187 Q7ZXC9 2.93e-156 Ribose-phosphate pyrophosphokinase 2 (EC 2.7.6.1) (Phosphoribosyl pyrophosphate synthase II) (PRS-II) Xenopus laevis (African clawed frog) 5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleotide biosynthetic process [GO:0009165]; phosphorylation [GO:0016310]; ribonucleoside monophosphate biosynthetic process [GO:0009156] GO:0000287; GO:0004749; GO:0005524; GO:0006015; GO:0009156; GO:0009165; GO:0016301; GO:0016310; GO:0042803 34351 XM_044326158.1 6 2 0 0 0 NA NA NA NA NA NA 34352 XM_029356767.2 1551 1547 747 956 1078 Q6PDY2 5.8e-34 2-aminoethanethiol dioxygenase (EC 1.13.11.19) (Cysteamine dioxygenase) Mus musculus (Mouse) cellular response to hypoxia [GO:0071456] GO:0005506; GO:0005739; GO:0047800; GO:0071456 34353 XM_044312316.1 0 0 8 0 0 NA NA NA NA NA NA 34354 XM_029325797.2 62 8 63 0 183 Q5RJA1 8.67e-146 DNA-binding protein RFX6 (Regulatory factor X 6) Danio rerio (Zebrafish) (Brachydanio rerio) endocrine pancreas development [GO:0031018]; glucose homeostasis [GO:0042593]; pancreatic A cell differentiation [GO:0003310]; pancreatic D cell differentiation [GO:0003311]; pancreatic epsilon cell differentiation [GO:0090104]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of insulin secretion [GO:0050796]; regulation of transcription by RNA polymerase II [GO:0006357]; type B pancreatic cell differentiation [GO:0003309] GO:0000976; GO:0000978; GO:0000981; GO:0003309; GO:0003310; GO:0003311; GO:0005634; GO:0006357; GO:0031018; GO:0035774; GO:0042593; GO:0045893; GO:0045944; GO:0050796; GO:0090104 34355 XM_044321104.1 47 16 23 63 63 Q91Y77 2.44e-26 Monocarboxylate transporter 10 (MCT 10) (Aromatic amino acid transporter 1) (Solute carrier family 16 member 10) (T-type amino acid transporter 1) Rattus norvegicus (Rat) aromatic amino acid transport [GO:0015801]; thyroid hormone generation [GO:0006590]; thyroid hormone transport [GO:0070327]; thyroid-stimulating hormone secretion [GO:0070460] GO:0005302; GO:0005886; GO:0006590; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0070327; GO:0070460 34356 XM_044313895.1 163 47 8 41 137 NA NA NA NA NA NA 34357 XR_006395119.1 1 7 0 29 32 NA NA NA NA NA NA 34358 XM_029358485.2 241 145 0 193 338 NA NA NA NA NA NA 34359 XM_029356185.2 34 20 13 23 19 NA NA NA NA NA NA 34360 XM_029341077.2 665 722 246 704 411 F1QWW8 8.12e-89 NA NA NA NA 34361 XM_044319776.1 147 64 106 196 208 Q90WU3 0 ATP-dependent RNA helicase DDX1 (EC 3.6.4.13) (DEAD box protein 1) Gallus gallus (Chicken) DNA duplex unwinding [GO:0032508]; double-strand break repair [GO:0006302]; mRNA processing [GO:0006397]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388] GO:0003677; GO:0003682; GO:0003712; GO:0003724; GO:0004518; GO:0004527; GO:0005524; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0006302; GO:0006388; GO:0006397; GO:0008143; GO:0016887; GO:0032508; GO:0033677; GO:0072669 34362 XM_044320346.1 309 0 237 0 0 NA NA NA NA NA NA 34363 XM_044316732.1 212 223 119 100 122 P02598 1.5e-30 Calmodulin (CaM) Tetrahymena pyriformis NA GO:0005509 34364 XM_029349482.2 1632 2098 1660 3246 1374 Q27128 0 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase (PAPS synthase) (PAPS synthetase) (PAPSS) (Sulfurylase kinase) (SK) [Includes: Sulfate adenylyltransferase (EC 2.7.7.4) (ATP-sulfurylase) (Sulfate adenylate transferase) (SAT); Adenylyl-sulfate kinase (EC 2.7.1.25) (3'-phosphoadenosine-5'-phosphosulfate synthase) (APS kinase) (Adenosine-5'-phosphosulfate 3'-phosphotransferase) (Adenylylsulfate 3'-phosphotransferase)] Urechis caupo (Innkeeper worm) (Spoonworm) phosphorylation [GO:0016310]; sulfate assimilation [GO:0000103] GO:0000103; GO:0004020; GO:0004781; GO:0005524; GO:0016310; GO:0016779 34365 XM_029334040.2 1222 707 1225 865 1146 NA NA NA NA NA NA 34366 XM_044316089.1 0 0 0 0 8 NA NA NA NA NA NA 34367 XM_044318954.1 117 547 161 176 598 P07607 1.02e-163 Thymidylate synthase (TS) (TSase) (EC 2.1.1.45) Mus musculus (Mouse) aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; methylation [GO:0032259]; negative regulation of translation [GO:0017148]; regulation of translation [GO:0006417]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to toxic substance [GO:0009636]; response to vitamin A [GO:0033189]; response to xenobiotic stimulus [GO:0009410]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860] GO:0000900; GO:0003729; GO:0004799; GO:0005542; GO:0005634; GO:0005730; GO:0005737; GO:0005739; GO:0005743; GO:0005759; GO:0005829; GO:0006231; GO:0006235; GO:0006417; GO:0007568; GO:0007623; GO:0009410; GO:0009636; GO:0017148; GO:0019860; GO:0032259; GO:0032570; GO:0033189; GO:0034097; GO:0035999; GO:0042803; GO:0045471; GO:0046683; GO:0048589; GO:0051216; GO:0051384; GO:0051593; GO:0060574; GO:0097421; GO:1901363; GO:1990825 34368 XM_044319581.1 0 17 0 1 156 O94762 1.24e-163 ATP-dependent DNA helicase Q5 (EC 3.6.4.12) (DNA helicase, RecQ-like type 5) (RecQ5) (RecQ protein-like 5) Homo sapiens (Human) cell division [GO:0051301]; cellular response to camptothecin [GO:0072757]; cellular response to ketone [GO:1901655]; cellular response to xenobiotic stimulus [GO:0071466]; chromosome separation [GO:0051304]; DNA duplex unwinding [GO:0032508]; DNA metabolic process [GO:0006259]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724]; mitotic cell cycle [GO:0000278]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; negative regulation of transcription elongation by RNA polymerase II [GO:0034244]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414] GO:0000278; GO:0000724; GO:0000993; GO:0003676; GO:0003678; GO:0005524; GO:0005634; GO:0005654; GO:0005694; GO:0005737; GO:0005829; GO:0006259; GO:0006260; GO:0006268; GO:0006281; GO:0006310; GO:0009378; GO:0016591; GO:0016887; GO:0032508; GO:0034244; GO:0042802; GO:0043138; GO:0051301; GO:0051304; GO:0071466; GO:0072757; GO:1901655; GO:1990414; GO:2000042 34369 XM_044307613.1 18 0 2 82 101 NA NA NA NA NA NA 34370 XM_044320775.1 44 42 14 25 9 NA NA NA NA NA NA 34371 XM_044308820.1 74 15 135 55 153 NA NA NA NA NA NA 34372 XM_029341471.2 66 47 20 125 50 NA NA NA NA NA NA 34373 XM_044314197.1 27 20 0 99 43 NA NA NA NA NA NA 34374 XM_044308906.1 19 11 7 10 15 NA NA NA NA NA NA 34375 XM_044312101.1 467 401 84 184 45 NA NA NA NA NA NA 34376 XM_029349858.2 11 6 18 15 28 Q8WVB3 1.6e-97 Hexosaminidase D (EC 3.2.1.52) (Beta-N-acetylhexosaminidase) (Beta-hexosaminidase D) (Hexosaminidase domain-containing protein) (N-acetyl-beta-galactosaminidase) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975] GO:0004563; GO:0005634; GO:0005737; GO:0005975; GO:0015929; GO:0102148; GO:1903561 34377 XM_029323548.2 67 14 1 54 60 P0C6B8 0 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 34378 XM_029323548.2 67 14 1 54 60 P0C6B8 4.12e-57 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 34379 XM_029323548.2 67 14 1 54 60 P0C6B8 3.47e-52 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 34380 XM_029323548.2 67 14 1 54 60 P0C6B8 2.17e-49 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 34381 XM_029323548.2 67 14 1 54 60 P0C6B8 6.97e-49 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 34382 XM_029323548.2 67 14 1 54 60 P0C6B8 1.52e-45 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 34383 XM_029323548.2 67 14 1 54 60 P0C6B8 2.74e-42 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 34384 XM_029323548.2 67 14 1 54 60 P0C6B8 3.67e-42 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 34385 XM_029323548.2 67 14 1 54 60 P0C6B8 2.41e-41 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 34386 XM_029323548.2 67 14 1 54 60 P0C6B8 2.02e-40 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 34387 XM_029323548.2 67 14 1 54 60 P0C6B8 1.52e-39 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 34388 XM_029323548.2 67 14 1 54 60 P0C6B8 6.3e-37 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 34389 XM_029323548.2 67 14 1 54 60 P0C6B8 2.87e-29 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 34390 XM_029323548.2 67 14 1 54 60 P0C6B8 5.12e-26 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 34391 XM_029324589.2 270 397 134 285 313 Q3KNI6 7.18e-29 Dynein axonemal assembly factor 6 (PIH1 domain-containing protein 3) Mus musculus (Mouse) axonemal dynein complex assembly [GO:0070286]; cilium movement [GO:0003341]; flagellated sperm motility [GO:0030317]; inner dynein arm assembly [GO:0036159]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0005737; GO:0005802; GO:0030317; GO:0036158; GO:0036159; GO:0045505; GO:0051087; GO:0070286 34392 XM_044319568.1 48 2 6 4 1 O43422 5.42e-44 52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (Death-associated protein 4) (THAP domain-containing protein 0) (THAP domain-containing protein 12) Homo sapiens (Human) negative regulation of cell population proliferation [GO:0008285]; signal transduction [GO:0007165] GO:0003677; GO:0005634; GO:0007165; GO:0008285; GO:0046872; GO:0046983 34393 XM_044327034.1 0 0 6 41 0 Q6P6B7 3.38e-78 Ankyrin repeat domain-containing protein 16 Homo sapiens (Human) tRNA modification [GO:0006400] GO:0005634; GO:0005737; GO:0006400 34394 XM_044324857.1 6 7 7 17 0 Q9H8P0 3.41e-37 Polyprenol reductase (EC 1.3.1.94) (3-oxo-5-alpha-steroid 4-dehydrogenase 3) (EC 1.3.1.22) (Steroid 5-alpha-reductase 2-like) (Steroid 5-alpha-reductase 3) (S5AR 3) (SR type 3) Homo sapiens (Human) androgen biosynthetic process [GO:0006702]; dolichol biosynthetic process [GO:0019408]; dolichol metabolic process [GO:0019348]; dolichol-linked oligosaccharide biosynthetic process [GO:0006488]; dolichyl diphosphate biosynthetic process [GO:0006489]; polyprenol catabolic process [GO:0016095] GO:0003865; GO:0005783; GO:0005789; GO:0006488; GO:0006489; GO:0006702; GO:0016095; GO:0016628; GO:0019348; GO:0019408; GO:0047751; GO:0102389 34395 XM_029339256.2 1564 5350 904 3063 582 NA NA NA NA NA NA 34396 XM_029350841.2 15 0 6 3 3 NA NA NA NA NA NA 34397 XM_044320216.1 695 164 403 856 131 NA NA NA NA NA NA 34398 XM_029355723.2 935 422 633 443 273 Q0IH87 1.51e-68 Paired box protein Pax-3-B (xPax3-B) (Paired-domain transcription factor Pax3-B) Xenopus laevis (African clawed frog) fibroblast growth factor receptor signaling pathway [GO:0008543]; hatching gland development [GO:0048785]; nervous system development [GO:0007399]; neural crest cell fate commitment [GO:0014034]; neural crest formation [GO:0014029]; positive regulation of DNA-templated transcription [GO:0045893]; Wnt signaling pathway [GO:0016055] GO:0000981; GO:0003677; GO:0005634; GO:0007399; GO:0008543; GO:0014029; GO:0014034; GO:0016055; GO:0045893; GO:0048785 34399 XM_029345632.2 1692 2224 864 1738 837 O95620 6.33e-130 tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like (EC 1.3.1.90) (pp35) (tRNA-dihydrouridine synthase 4-like) Homo sapiens (Human) tRNA dihydrouridine synthesis [GO:0002943] GO:0002943; GO:0017150; GO:0050660 34400 XR_006393954.1 25 19 18 18 47 NA NA NA NA NA NA 34401 XR_006393334.1 106 29 102 98 153 NA NA NA NA NA NA 34402 XR_003823959.2 0 123 31 25 155 NA NA NA NA NA NA 34403 XM_029323449.2 875 977 532 500 580 NA NA NA NA NA NA 34404 XM_029330953.2 755 559 436 710 530 NA NA NA NA NA NA 34405 XR_006391557.1 40 176 47 124 95 NA NA NA NA NA NA 34406 XM_044317687.1 52 18 8 9 8 NA NA NA NA NA NA 34407 XM_029352719.2 53 31 68 72 67 NA NA NA NA NA NA 34408 XM_029338188.2 834 992 482 662 369 A4FV54 6.45e-71 Ras-related protein Rab-8A (EC 3.6.5.2) Bos taurus (Bovine) autophagy [GO:0006914]; axonogenesis [GO:0007409]; cellular response to insulin stimulus [GO:0032869]; cilium assembly [GO:0060271]; endocytic recycling [GO:0032456]; Golgi organization [GO:0007030]; Golgi vesicle fusion to target membrane [GO:0048210]; neurotransmitter receptor transport to postsynaptic membrane [GO:0098969]; protein localization to cilium [GO:0061512]; protein localization to plasma membrane [GO:0072659]; protein secretion [GO:0009306]; regulation of autophagy [GO:0010506]; regulation of exocytosis [GO:0017157]; vesicle docking involved in exocytosis [GO:0006904] GO:0003924; GO:0005525; GO:0005768; GO:0005794; GO:0005813; GO:0005814; GO:0005886; GO:0005929; GO:0006904; GO:0006914; GO:0007030; GO:0007409; GO:0008021; GO:0009306; GO:0010506; GO:0017157; GO:0019003; GO:0030140; GO:0030496; GO:0030670; GO:0031267; GO:0031489; GO:0032456; GO:0032869; GO:0036064; GO:0043197; GO:0043231; GO:0045335; GO:0048210; GO:0055038; GO:0060170; GO:0060271; GO:0061512; GO:0072659; GO:0097546; GO:0097730; GO:0098969 34409 XM_044309795.1 271 193 0 0 787 Q8R4V5 4.91e-27 Oncoprotein-induced transcript 3 protein (Liver-specific zona pellucida domain-containing protein) Mus musculus (Mouse) urate homeostasis [GO:1903118] GO:0005201; GO:0005509; GO:0005615; GO:0005635; GO:0009986; GO:1903118 34410 XM_044309058.1 0 0 0 2 25 Q3UQ28 9.2e-32 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 34411 XM_044309058.1 0 0 0 2 25 Q3UQ28 2.05e-28 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 34412 XM_044316320.1 45 22 27 20 89 NA NA NA NA NA NA 34413 XM_029328827.2 304 226 195 419 209 P15848 1.46e-141 Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S) Homo sapiens (Human) autophagy [GO:0006914]; central nervous system development [GO:0007417]; colon epithelial cell migration [GO:0061580]; lysosomal transport [GO:0007041]; lysosome organization [GO:0007040]; positive regulation of neuron projection development [GO:0010976]; regulation of epithelial cell migration [GO:0010632]; response to estrogen [GO:0043627]; response to methylmercury [GO:0051597]; response to nutrient [GO:0007584]; response to pH [GO:0009268] GO:0003943; GO:0004065; GO:0005576; GO:0005739; GO:0005764; GO:0005788; GO:0005791; GO:0005794; GO:0006914; GO:0007040; GO:0007041; GO:0007417; GO:0007584; GO:0009268; GO:0009986; GO:0010632; GO:0010976; GO:0035578; GO:0043202; GO:0043627; GO:0046872; GO:0051597; GO:0061580; GO:0070062; GO:1904813 34414 XM_044317858.1 85 6 0 87 0 NA NA NA NA NA NA 34415 XM_029336329.2 806 663 362 647 721 Q5BK48 1.39e-113 Tetratricopeptide repeat protein 5 (TPR repeat protein 5) (Stress-responsive activator of p300) (Protein Strap) Rattus norvegicus (Rat) cellular response to DNA damage stimulus [GO:0006974]; cellular response to starvation [GO:0009267]; DNA repair [GO:0006281]; positive regulation of mRNA catabolic process [GO:0061014]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0003677; GO:0003682; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005759; GO:0005829; GO:0006281; GO:0006974; GO:0009267; GO:0031410; GO:0043022; GO:0045944; GO:0061014 34416 XM_044308005.1 0 3898 4047 1167 268 NA NA NA NA NA NA 34417 XM_029324643.2 625 315 371 471 565 Q8CA95 0 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (EC 3.1.4.17) Mus musculus (Mouse) cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0106070]; regulation of protein kinase A signaling [GO:0010738]; signal transduction [GO:0007165] GO:0004112; GO:0004114; GO:0004115; GO:0004118; GO:0005829; GO:0006198; GO:0007165; GO:0010738; GO:0010754; GO:0016020; GO:0030552; GO:0030553; GO:0043025; GO:0043204; GO:0043951; GO:0046069; GO:0046872; GO:0047555; GO:0106070 34418 XM_044325461.1 72 46 23 52 35 NA NA NA NA NA NA 34419 XM_044326821.1 10 0 0 58 96 NA NA NA NA NA NA 34420 XM_044325973.1 55 0 18 2 156 NA NA NA NA NA NA 34421 XM_044315027.1 28 209 138 419 320 NA NA NA NA NA NA 34422 XM_029329515.2 21 10 12 27 13 F1R332 3.39e-23 Galanin receptor 2a Danio rerio (Zebrafish) (Brachydanio rerio) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; neuropeptide signaling pathway [GO:0007218] GO:0004966; GO:0005886; GO:0007188; GO:0007218; GO:0008528 34423 XM_044309794.1 83 0 420 0 44 Q8R4V5 2.49e-27 Oncoprotein-induced transcript 3 protein (Liver-specific zona pellucida domain-containing protein) Mus musculus (Mouse) urate homeostasis [GO:1903118] GO:0005201; GO:0005509; GO:0005615; GO:0005635; GO:0009986; GO:1903118 34424 XM_029324867.2 821 843 340 543 422 Q9CQJ4 1.38e-130 E3 ubiquitin-protein ligase RING2 (EC 2.3.2.27) (RING finger protein 1B) (RING1b) (RING finger protein 2) (RING-type E3 ubiquitin transferase RING2) Mus musculus (Mouse) anterior/posterior axis specification [GO:0009948]; chromatin remodeling [GO:0006338]; gastrulation with mouth forming second [GO:0001702]; gene expression [GO:0010467]; germ cell development [GO:0007281]; histone H2A monoubiquitination [GO:0035518]; histone H2A-K119 monoubiquitination [GO:0036353]; histone ubiquitination [GO:0016574]; mitotic cell cycle [GO:0000278]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122] GO:0000122; GO:0000151; GO:0000278; GO:0000791; GO:0000792; GO:0001702; GO:0001739; GO:0003682; GO:0004842; GO:0005634; GO:0005654; GO:0005737; GO:0006338; GO:0007281; GO:0008270; GO:0009948; GO:0010467; GO:0016574; GO:0016604; GO:0031519; GO:0035102; GO:0035518; GO:0036353; GO:0043433; GO:0061630; GO:0071339; GO:0071535 34425 XM_044314692.1 0 7 4 6 0 NA NA NA NA NA NA 34426 XM_044319417.1 15 2 2 5 8 NA NA NA NA NA NA 34427 XM_029338649.2 54 0 70 0 0 NA NA NA NA NA NA 34428 XM_044317014.1 110 479 134 472 198 Q9N126 1.82e-64 Retinol dehydrogenase 8 (EC 1.1.1.300) (Photoreceptor outer segment all-trans retinol dehydrogenase) Bos taurus (Bovine) estrogen biosynthetic process [GO:0006703]; response to stimulus [GO:0050896]; retinol metabolic process [GO:0042572]; visual perception [GO:0007601] GO:0004303; GO:0004745; GO:0005829; GO:0006703; GO:0007601; GO:0016491; GO:0042572; GO:0042622; GO:0050896; GO:0052650 34429 XM_044315701.1 24 15 86 79 33 P35546 3.02e-80 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; anatomical structure morphogenesis [GO:0009653]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006919; GO:0007156; GO:0007158; GO:0007169; GO:0007399; GO:0009410; GO:0009653; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030182; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0098797; GO:2001241 34430 XM_029352211.2 16 17 35 22 57 NA NA NA NA NA NA 34431 XR_006396518.1 102 48 34 23 70 NA NA NA NA NA NA 34432 XM_029346014.2 213 0 258 0 3 Q9VBW3 4.79e-82 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 34433 XM_029352605.2 0 11 0 0 0 P48040 1.39e-24 Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor) Ovis aries (Sheep) NA GO:0005886; GO:0008502 34434 XM_029335037.2 11 8 0 13 10 O94766 8.86e-82 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 (EC 2.4.1.135) (Beta-1,3-glucuronyltransferase 3) (Glucuronosyltransferase I) (GlcAT-I) (UDP-GlcUA:Gal beta-1,3-Gal-R glucuronyltransferase) (GlcUAT-I) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; chondroitin sulfate proteoglycan biosynthetic process [GO:0050650]; dermatan sulfate proteoglycan biosynthetic process [GO:0050651]; glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; positive regulation of catalytic activity [GO:0043085]; positive regulation of intracellular protein transport [GO:0090316]; protein glycosylation [GO:0006486] GO:0000139; GO:0005794; GO:0005801; GO:0005975; GO:0006024; GO:0006486; GO:0015012; GO:0015018; GO:0015020; GO:0016020; GO:0043085; GO:0046872; GO:0050650; GO:0050651; GO:0070062; GO:0072542; GO:0090316 34435 XM_044308579.1 11 31 10 20 21 NA NA NA NA NA NA 34436 XM_029335634.2 157 413 108 333 75 Q8BKD6 5.61e-63 E3 ubiquitin-protein ligase RNF144B (EC 2.3.2.31) (IBR domain-containing protein 2) (RING finger protein 144B) Mus musculus (Mouse) apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000151; GO:0000209; GO:0004842; GO:0005737; GO:0006511; GO:0006915; GO:0031624; GO:0031966; GO:0032436; GO:0043066; GO:0046872; GO:0061630 34437 XM_029330382.2 94 99 89 43 80 Q8NB15 2.68e-43 Zinc finger protein 511 Homo sapiens (Human) NA GO:0003677; GO:0005634; GO:0046872 34438 XM_029330427.2 21 2 2 24 76 NA NA NA NA NA NA 34439 XM_029331548.2 1218 971 650 804 400 Q6AYP4 1.34e-28 Zinc finger C2HC domain-containing protein 1C Rattus norvegicus (Rat) NA GO:0046872 34440 XM_029330651.2 1613 1285 842 1126 1177 B5XGE7 9.29e-71 Trafficking protein particle complex subunit 2-like protein Salmo salar (Atlantic salmon) COPII vesicle coating [GO:0048208]; vesicle tethering [GO:0099022] GO:0005783; GO:0048208; GO:0048471; GO:0099022; GO:1990071; GO:1990072 34441 XM_029346631.2 75 104 66 110 99 NA NA NA NA NA NA 34442 XM_044310342.1 4 0 0 0 10 NA NA NA NA NA NA 34443 XM_029330675.2 270 639 384 1026 316 Q9I9A7 1.1e-93 DNA replication factor Cdt1 (XCDT1) Xenopus laevis (African clawed frog) DNA replication preinitiation complex assembly [GO:0071163]; regulation of DNA-templated DNA replication initiation [GO:0030174] GO:0005634; GO:0030174; GO:0031490; GO:0071163 34444 XM_044327380.1 50 15 11 14 15 NA NA NA NA NA NA 34445 XM_044322073.1 651 979 669 909 857 Q5R5W2 2.21e-76 TAR DNA-binding protein 43 (TDP-43) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) mRNA processing [GO:0006397]; regulation of circadian rhythm [GO:0042752]; regulation of protein stability [GO:0031647]; RNA splicing [GO:0008380] GO:0003677; GO:0003723; GO:0005694; GO:0005730; GO:0005739; GO:0006397; GO:0008380; GO:0016607; GO:0031647; GO:0042752 34446 XM_044324305.1 3238 327 249 1950 565 P49961 2.62e-48 Ectonucleoside triphosphate diphosphohydrolase 1 (NTPDase 1) (EC 3.6.1.5) (Ecto-ATP diphosphohydrolase 1) (Ecto-ATPDase 1) (Ecto-ATPase 1) (Ecto-apyrase) (Lymphoid cell activation antigen) (CD antigen CD39) Homo sapiens (Human) blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; nucleoside diphosphate catabolic process [GO:0009134] GO:0004382; GO:0005524; GO:0005886; GO:0007155; GO:0007596; GO:0009134; GO:0016020; GO:0017110; GO:0045134; GO:0070062 34447 XM_044316941.1 0 0 0 0 13 NA NA NA NA NA NA 34448 XM_029334296.2 0 0 0 8 56 NA NA NA NA NA NA 34449 XM_044316471.1 2 0 0 0 9 NA NA NA NA NA NA 34450 XM_044313461.1 9 0 13 27 46 O43422 1.11e-83 52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (Death-associated protein 4) (THAP domain-containing protein 0) (THAP domain-containing protein 12) Homo sapiens (Human) negative regulation of cell population proliferation [GO:0008285]; signal transduction [GO:0007165] GO:0003677; GO:0005634; GO:0007165; GO:0008285; GO:0046872; GO:0046983 34451 XM_029342035.2 432 105 129 42 1 Q90683 1.18e-35 Transcription factor 4 (TCF-4) (Class A helix-loop-helix transcription factor GE2) Gallus gallus (Chicken) positive regulation of neuron differentiation [GO:0045666]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005667; GO:0006357; GO:0045666; GO:0046982; GO:0070888 34452 XM_029329354.2 709 814 149 928 247 O08873 3.63e-161 MAP kinase-activating death domain protein (Rab3 GDP/GTP exchange factor) (RabGEF) (Rab3 GDP/GTP exchange protein) (RabGEP) Rattus norvegicus (Rat) anterograde synaptic vesicle transport [GO:0048490]; execution phase of apoptosis [GO:0097194]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of growth hormone secretion [GO:0060125]; negative regulation of pancreatic amylase secretion [GO:1902277]; positive regulation of MAPK cascade [GO:0043410]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of extrinsic apoptotic signaling pathway [GO:2001236]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of Rab protein signal transduction [GO:0032483] GO:0005085; GO:0005634; GO:0005829; GO:0005886; GO:0008021; GO:0016020; GO:0030424; GO:0032483; GO:0042981; GO:0043410; GO:0045202; GO:0048490; GO:0051726; GO:0060125; GO:0097194; GO:1902041; GO:1902277; GO:1904115; GO:2001234; GO:2001236 34453 XM_029329354.2 709 814 149 928 247 O08873 1.14e-123 MAP kinase-activating death domain protein (Rab3 GDP/GTP exchange factor) (RabGEF) (Rab3 GDP/GTP exchange protein) (RabGEP) Rattus norvegicus (Rat) anterograde synaptic vesicle transport [GO:0048490]; execution phase of apoptosis [GO:0097194]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of growth hormone secretion [GO:0060125]; negative regulation of pancreatic amylase secretion [GO:1902277]; positive regulation of MAPK cascade [GO:0043410]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of extrinsic apoptotic signaling pathway [GO:2001236]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of Rab protein signal transduction [GO:0032483] GO:0005085; GO:0005634; GO:0005829; GO:0005886; GO:0008021; GO:0016020; GO:0030424; GO:0032483; GO:0042981; GO:0043410; GO:0045202; GO:0048490; GO:0051726; GO:0060125; GO:0097194; GO:1902041; GO:1902277; GO:1904115; GO:2001234; GO:2001236 34454 XM_029329354.2 709 814 149 928 247 O08873 1.88e-21 MAP kinase-activating death domain protein (Rab3 GDP/GTP exchange factor) (RabGEF) (Rab3 GDP/GTP exchange protein) (RabGEP) Rattus norvegicus (Rat) anterograde synaptic vesicle transport [GO:0048490]; execution phase of apoptosis [GO:0097194]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of growth hormone secretion [GO:0060125]; negative regulation of pancreatic amylase secretion [GO:1902277]; positive regulation of MAPK cascade [GO:0043410]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of extrinsic apoptotic signaling pathway [GO:2001236]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of Rab protein signal transduction [GO:0032483] GO:0005085; GO:0005634; GO:0005829; GO:0005886; GO:0008021; GO:0016020; GO:0030424; GO:0032483; GO:0042981; GO:0043410; GO:0045202; GO:0048490; GO:0051726; GO:0060125; GO:0097194; GO:1902041; GO:1902277; GO:1904115; GO:2001234; GO:2001236 34455 XR_003828064.2 0 7 0 0 0 NA NA NA NA NA NA 34456 XM_044307698.1 0 9 0 28 12 NA NA NA NA NA NA 34457 XM_029346098.2 952 1376 3418 4451 2990 Q10738 6.01e-45 Matrilysin (EC 3.4.24.23) (Matrin) (Matrix metalloproteinase-7) (MMP-7) (Pump-1 protease) (Uterine metalloproteinase) Mus musculus (Mouse) antibacterial peptide biosynthetic process [GO:0002780]; antibacterial peptide secretion [GO:0002779]; collagen catabolic process [GO:0030574]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; extracellular matrix organization [GO:0030198]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell population proliferation [GO:0042127]; response to xenobiotic stimulus [GO:0009410] GO:0002779; GO:0002780; GO:0004175; GO:0004222; GO:0005576; GO:0005615; GO:0006508; GO:0006509; GO:0008201; GO:0008233; GO:0008237; GO:0008270; GO:0009410; GO:0009986; GO:0030198; GO:0030335; GO:0030574; GO:0031012; GO:0031293; GO:0042127; GO:0042742; GO:0050829; GO:0050830 34458 XR_006397135.1 0 5 48 0 33 NA NA NA NA NA NA 34459 XM_044319788.1 141 0 51 89 82 Q8R151 2.49e-131 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 34460 XM_044319788.1 141 0 51 89 82 Q8R151 2.42e-79 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 34461 XM_044319788.1 141 0 51 89 82 Q8R151 8.16e-72 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 34462 XM_044319788.1 141 0 51 89 82 Q8R151 9.59e-23 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 34463 XM_044329090.1 28 23 12 40 54 NA NA NA NA NA NA 34464 XM_029353875.2 178 241 305 308 424 NA NA NA NA NA NA 34465 XM_029330268.2 3 0 9 0 7 NA NA NA NA NA NA 34466 XR_006396134.1 0 0 0 17 0 P0C0R5 4.19e-25 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) Rattus norvegicus (Rat) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006623; GO:0010506; GO:0015630; GO:0016236; GO:0016241; GO:0030242; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 34467 XM_029354961.2 279 104 124 159 145 O95427 0 GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (MCD4 homolog) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N) Homo sapiens (Human) GPI anchor biosynthetic process [GO:0006506]; preassembly of GPI anchor in ER membrane [GO:0016254] GO:0005789; GO:0005829; GO:0005886; GO:0006506; GO:0016020; GO:0016254; GO:0051377 34468 XM_029336847.2 610 920 590 658 571 Q3MII6 4.26e-93 TBC1 domain family member 25 Homo sapiens (Human) activation of GTPase activity [GO:0090630]; autophagy [GO:0006914]; regulation of autophagosome maturation [GO:1901096] GO:0005096; GO:0005776; GO:0006914; GO:0031410; GO:0090630; GO:1901096 34469 XM_044310417.1 0 0 16 4 63 P06803 2.35e-52 Serine/threonine-protein kinase pim-1 (EC 2.7.11.1) Mus musculus (Mouse) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cellular detoxification [GO:1990748]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cardioblast proliferation [GO:1905062]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of transmembrane transporter activity [GO:0022898]; vitamin D receptor signaling pathway [GO:0070561] GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0005886; GO:0006468; GO:0006915; GO:0007049; GO:0022898; GO:0030145; GO:0043024; GO:0043066; GO:0043433; GO:0043539; GO:0045737; GO:0045893; GO:0046777; GO:0050821; GO:0060045; GO:0070561; GO:0071902; GO:0090336; GO:0106310; GO:1902033; GO:1905062; GO:1990748 34470 XM_044325535.1 0 0 0 79 123 B1AS29 8.27e-83 Glutamate receptor ionotropic, kainate 3 (GluK3) (Glutamate receptor 7) (GluR-7) (GluR7) Mus musculus (Mouse) G protein-coupled glutamate receptor signaling pathway [GO:0007216]; glutamate receptor signaling pathway [GO:0007215]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; regulation of membrane potential [GO:0042391]; synaptic transmission, glutamatergic [GO:0035249] GO:0001640; GO:0004970; GO:0005886; GO:0007215; GO:0007216; GO:0008066; GO:0015276; GO:0015277; GO:0030424; GO:0030425; GO:0032839; GO:0032983; GO:0035249; GO:0038023; GO:0042391; GO:0042734; GO:0043195; GO:0043204; GO:0045211; GO:0050804; GO:0051967; GO:0098978; GO:0099507; GO:1904315 34471 XM_029354630.2 74 9 64 139 121 C6FG12 1.11e-23 Protein NLRC5 Ictalurus punctatus (Channel catfish) (Silurus punctatus) innate immune response [GO:0045087] GO:0005524; GO:0005737; GO:0045087 34472 XM_044307723.1 10 0 4 113 74 NA NA NA NA NA NA 34473 XM_029351302.2 25 10 9 21 22 NA NA NA NA NA NA 34474 XM_029337108.2 362 72 111 128 189 A2RV80 1.64e-69 GRAM domain-containing protein 4 Xenopus laevis (African clawed frog) apoptotic process [GO:0006915] GO:0005789; GO:0006915; GO:0031966 34475 XR_006393310.1 29 16 0 0 47 NA NA NA NA NA NA 34476 XM_044310268.1 0 0 1 0 6 NA NA NA NA NA NA 34477 XR_006396474.1 0 8 8 5 0 NA NA NA NA NA NA 34478 XM_029343681.2 14 0 16 4 49 NA NA NA NA NA NA 34479 XM_044312959.1 0 0 179 381 0 Q9NZM1 0 Myoferlin (Fer-1-like protein 3) Homo sapiens (Human) blood circulation [GO:0008015]; membrane fusion [GO:0061025]; muscle contraction [GO:0006936]; plasma membrane organization [GO:0007009]; plasma membrane repair [GO:0001778]; T-tubule organization [GO:0033292] GO:0001778; GO:0005543; GO:0005635; GO:0005886; GO:0005901; GO:0006936; GO:0007009; GO:0008015; GO:0030659; GO:0031410; GO:0031965; GO:0033292; GO:0043231; GO:0046872; GO:0061025; GO:0070062 34480 XM_044319981.1 9 2 6 0 33 NA NA NA NA NA NA 34481 XM_029329152.2 750 639 368 592 505 Q9WVA3 0 Mitotic checkpoint protein BUB3 (WD repeat type I transmembrane protein A72.5) Mus musculus (Mouse) attachment of spindle microtubules to kinetochore [GO:0008608]; cell division [GO:0051301]; meiotic cell cycle [GO:0051321]; mitotic spindle assembly checkpoint signaling [GO:0007094]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; protein localization to kinetochore [GO:0034501]; regulation of chromosome segregation [GO:0051983] GO:0000776; GO:0005654; GO:0007094; GO:0008608; GO:0033597; GO:0034501; GO:0043130; GO:0051301; GO:0051321; GO:0051444; GO:0051983; GO:1990298 34482 XM_029348742.2 4390 3583 1798 3024 3015 Q9UPZ9 4.51e-169 Serine/threonine-protein kinase ICK (EC 2.7.11.1) (Ciliogenesis associated kinase 1) (Intestinal cell kinase) (hICK) (Laryngeal cancer kinase 2) (LCK2) (MAK-related kinase) (MRK) Homo sapiens (Human) cilium assembly [GO:0060271]; intracellular signal transduction [GO:0035556]; intraciliary anterograde transport [GO:0035720]; intraciliary retrograde transport [GO:0035721]; intraciliary transport [GO:0042073]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165] GO:0000287; GO:0001650; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0005929; GO:0006468; GO:0007165; GO:0035556; GO:0035720; GO:0035721; GO:0036064; GO:0042073; GO:0060271; GO:0097542; GO:0097546; GO:0106310 34483 XM_029333492.2 432 250 274 658 828 Q03701 0 CCAAT/enhancer-binding protein zeta (CCAAT-box-binding transcription factor) (CBF) (CCAAT-binding factor) Homo sapiens (Human) positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0003713; GO:0003723; GO:0005634; GO:0016602; GO:0045944 34484 XM_044307495.1 32 4 1 22 22 NA NA NA NA NA NA 34485 XM_029329827.2 0 36 0 0 0 NA NA NA NA NA NA 34486 XM_029338149.2 0 118 62 330 768 Q8CBF3 0 Ephrin type-B receptor 1 (EC 2.7.10.1) Mus musculus (Mouse) angiogenesis [GO:0001525]; axon guidance [GO:0007411]; camera-type eye morphogenesis [GO:0048593]; cell chemotaxis [GO:0060326]; cell-substrate adhesion [GO:0031589]; central nervous system projection neuron axonogenesis [GO:0021952]; cranial nerve development [GO:0021545]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; ephrin receptor signaling pathway [GO:0048013]; establishment of cell polarity [GO:0030010]; hindbrain tangential cell migration [GO:0021934]; immunological synapse formation [GO:0001771]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of satellite cell differentiation [GO:1902725]; negative regulation of skeletal muscle satellite cell proliferation [GO:1902723]; neural precursor cell proliferation [GO:0061351]; neurogenesis [GO:0022008]; optic nerve morphogenesis [GO:0021631]; positive regulation of kinase activity [GO:0033674]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of neuron death [GO:1901214]; retinal ganglion cell axon guidance [GO:0031290]; skeletal muscle satellite cell activation [GO:0014719]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0001525; GO:0001771; GO:0004713; GO:0004714; GO:0005005; GO:0005524; GO:0005737; GO:0005783; GO:0005829; GO:0005886; GO:0007169; GO:0007411; GO:0008046; GO:0014719; GO:0016020; GO:0021545; GO:0021631; GO:0021934; GO:0021952; GO:0022008; GO:0030010; GO:0030424; GO:0030425; GO:0031290; GO:0031589; GO:0031901; GO:0032433; GO:0033674; GO:0043005; GO:0043235; GO:0044877; GO:0045121; GO:0046328; GO:0046777; GO:0048013; GO:0048593; GO:0050804; GO:0050965; GO:0051965; GO:0060326; GO:0060996; GO:0060997; GO:0061351; GO:0070372; GO:0098978; GO:1901214; GO:1902723; GO:1902725 34487 XM_044321524.1 515 240 293 34 280 NA NA NA NA NA NA 34488 XM_029334382.2 3718 3139 3458 3086 1886 Q96HN2 0 Adenosylhomocysteinase 3 (AdoHcyase 3) (EC 3.13.2.1) (IP(3)Rs binding protein released with IP(3) 2) (IRBIT2) (Long-IRBIT) (S-adenosyl-L-homocysteine hydrolase 3) (S-adenosylhomocysteine hydrolase-like protein 2) Homo sapiens (Human) one-carbon metabolic process [GO:0006730]; S-adenosylmethionine cycle [GO:0033353] GO:0005783; GO:0005829; GO:0006730; GO:0016787; GO:0033353; GO:0043005 34489 XM_029343965.2 1094 747 1116 1754 1697 Q9DE27 0 RuvB-like 2 (EC 3.6.4.12) (Reptin) Xenopus laevis (African clawed frog) DNA recombination [GO:0006310]; DNA repair [GO:0006281] GO:0000812; GO:0004386; GO:0005524; GO:0006281; GO:0006310; GO:0008094; GO:0016887; GO:0071339; GO:0120293 34490 XM_029335024.2 18 45 41 0 0 Q3TC93 2.1e-23 HCLS1-binding protein 3 (HS1-binding protein 3) (HSP1BP-3) Mus musculus (Mouse) cell surface receptor signaling pathway [GO:0007166]; regulation of apoptotic process [GO:0042981]; T cell differentiation [GO:0030217] GO:0005739; GO:0005783; GO:0007166; GO:0030217; GO:0035091; GO:0042981 34491 XM_044318114.1 218 0 73 57 102 Q6RI86 4.23e-119 Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Wasabi receptor) Rattus norvegicus (Rat) calcium ion transmembrane import into cytosol [GO:0097553]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cell surface receptor signaling pathway [GO:0007166]; cellular calcium ion homeostasis [GO:0006874]; cellular response to caffeine [GO:0071313]; cellular response to carbon dioxide [GO:0071244]; cellular response to cold [GO:0070417]; cellular response to heat [GO:0034605]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to organic substance [GO:0071310]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; ion transmembrane transport [GO:0034220]; positive regulation of anion transport [GO:1903793]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of sensory perception of pain [GO:1904058]; protein homotetramerization [GO:0051289]; regulation of blood circulation [GO:1903522]; regulation of neuronal action potential [GO:0098908]; response to cold [GO:0009409]; response to hydrogen peroxide [GO:0042542]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; sensory perception of pain [GO:0019233]; thermoception [GO:0050955]; transmembrane transport [GO:0055085]; urinary bladder smooth muscle contraction [GO:0014832] GO:0005216; GO:0005245; GO:0005262; GO:0005886; GO:0006816; GO:0006874; GO:0007166; GO:0009409; GO:0009410; GO:0010033; GO:0014070; GO:0014832; GO:0015267; GO:0015278; GO:0016324; GO:0019233; GO:0030424; GO:0032421; GO:0034220; GO:0034605; GO:0035774; GO:0042542; GO:0042802; GO:0048265; GO:0050955; GO:0050966; GO:0050968; GO:0050974; GO:0051289; GO:0055085; GO:0070301; GO:0070417; GO:0070588; GO:0071244; GO:0071310; GO:0071313; GO:0097553; GO:0097604; GO:0098908; GO:1903522; GO:1903793; GO:1904058; GO:1990760 34492 XM_029346589.2 324 268 228 387 404 A0MGZ5 6.29e-114 Heparan-sulfate 6-O-sulfotransferase 1-B (HS 6-OST-1B) (EC 2.8.2.-) Danio rerio (Zebrafish) (Brachydanio rerio) heparan sulfate proteoglycan biosynthetic process, enzymatic modification [GO:0015015] GO:0015015; GO:0016020; GO:0017095 34493 XM_029331297.2 422 370 236 269 672 NA NA NA NA NA NA 34494 XM_029340020.2 4373 6252 2676 3058 2290 Q2TA24 4.05e-66 V-type proton ATPase 21 kDa proteolipid subunit c'' (V-ATPase 21 kDa proteolipid subunit c'') (Vacuolar proton pump 21 kDa proteolipid subunit c'') Bos taurus (Bovine) pH reduction [GO:0045851]; proton transmembrane transport [GO:1902600] GO:0000220; GO:0005768; GO:0016020; GO:0030665; GO:0045851; GO:0046961; GO:1902495; GO:1902600; GO:1904949 34495 XM_029324507.2 69 106 118 176 141 NA NA NA NA NA NA 34496 XM_029331142.2 19 39 78 61 40 Q9BUZ4 9.19e-48 TNF receptor-associated factor 4 (EC 2.3.2.27) (Cysteine-rich domain associated with RING and Traf domains protein 1) (Metastatic lymph node gene 62 protein) (MLN 62) (RING finger protein 83) Homo sapiens (Human) activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; innate immune response [GO:0045087]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein kinase activity [GO:0045860]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; respiratory gaseous exchange by respiratory system [GO:0007585]; respiratory tube development [GO:0030323] GO:0001650; GO:0005164; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0005923; GO:0006915; GO:0007250; GO:0007585; GO:0008270; GO:0016740; GO:0019901; GO:0030323; GO:0031625; GO:0031996; GO:0042802; GO:0042981; GO:0043122; GO:0043161; GO:0045087; GO:0045860; GO:0046330; GO:0048471; GO:0050699 34497 XM_029332703.2 698 705 248 697 411 P42325 5.33e-68 Neurocalcin homolog (DrosNCa) Drosophila melanogaster (Fruit fly) negative regulation of neuronal signal transduction [GO:1902848]; positive regulation of circadian sleep/wake cycle, sleep [GO:0045938] GO:0005509; GO:0045938; GO:1902848 34498 XM_029337732.2 199 71 60 93 8 NA NA NA NA NA NA 34499 XM_029329809.2 0 83 82 72 197 NA NA NA NA NA NA 34500 XM_044310175.1 45 7 6 39 2 NA NA NA NA NA NA 34501 XR_006395730.1 25 73 49 28 150 NA NA NA NA NA NA 34502 XM_029355405.2 432 31 266 400 524 Q05793 0 Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG) [Cleaved into: Endorepellin; LG3 peptide] Mus musculus (Mouse) angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; brain development [GO:0007420]; cardiac muscle tissue development [GO:0048738]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; chondrocyte differentiation [GO:0002062]; embryonic skeletal system morphogenesis [GO:0048704]; endochondral ossification [GO:0001958]; extracellular matrix organization [GO:0030198]; negative regulation of amyloid fibril formation [GO:1905907]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell death [GO:0060548]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of endothelial cell proliferation [GO:0001938]; protein localization [GO:0008104]; receptor-mediated endocytosis [GO:0006898]; smoothened signaling pathway [GO:0007224]; tissue development [GO:0009888] GO:0001525; GO:0001938; GO:0001958; GO:0002020; GO:0002062; GO:0005509; GO:0005576; GO:0005604; GO:0005796; GO:0006898; GO:0007162; GO:0007224; GO:0007420; GO:0008022; GO:0008104; GO:0008285; GO:0009887; GO:0009888; GO:0030198; GO:0031012; GO:0048704; GO:0048738; GO:0060351; GO:0060548; GO:0062023; GO:0070052; GO:1905907 34503 XM_029355405.2 432 31 266 400 524 Q05793 0 Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG) [Cleaved into: Endorepellin; LG3 peptide] Mus musculus (Mouse) angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; brain development [GO:0007420]; cardiac muscle tissue development [GO:0048738]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; chondrocyte differentiation [GO:0002062]; embryonic skeletal system morphogenesis [GO:0048704]; endochondral ossification [GO:0001958]; extracellular matrix organization [GO:0030198]; negative regulation of amyloid fibril formation [GO:1905907]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell death [GO:0060548]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of endothelial cell proliferation [GO:0001938]; protein localization [GO:0008104]; receptor-mediated endocytosis [GO:0006898]; smoothened signaling pathway [GO:0007224]; tissue development [GO:0009888] GO:0001525; GO:0001938; GO:0001958; GO:0002020; GO:0002062; GO:0005509; GO:0005576; GO:0005604; GO:0005796; GO:0006898; GO:0007162; GO:0007224; GO:0007420; GO:0008022; GO:0008104; GO:0008285; GO:0009887; GO:0009888; GO:0030198; GO:0031012; GO:0048704; GO:0048738; GO:0060351; GO:0060548; GO:0062023; GO:0070052; GO:1905907 34504 XM_029355405.2 432 31 266 400 524 Q05793 6.72e-128 Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG) [Cleaved into: Endorepellin; LG3 peptide] Mus musculus (Mouse) angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; brain development [GO:0007420]; cardiac muscle tissue development [GO:0048738]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; chondrocyte differentiation [GO:0002062]; embryonic skeletal system morphogenesis [GO:0048704]; endochondral ossification [GO:0001958]; extracellular matrix organization [GO:0030198]; negative regulation of amyloid fibril formation [GO:1905907]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell death [GO:0060548]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of endothelial cell proliferation [GO:0001938]; protein localization [GO:0008104]; receptor-mediated endocytosis [GO:0006898]; smoothened signaling pathway [GO:0007224]; tissue development [GO:0009888] GO:0001525; GO:0001938; GO:0001958; GO:0002020; GO:0002062; GO:0005509; GO:0005576; GO:0005604; GO:0005796; GO:0006898; GO:0007162; GO:0007224; GO:0007420; GO:0008022; GO:0008104; GO:0008285; GO:0009887; GO:0009888; GO:0030198; GO:0031012; GO:0048704; GO:0048738; GO:0060351; GO:0060548; GO:0062023; GO:0070052; GO:1905907 34505 XM_029355405.2 432 31 266 400 524 Q05793 1.09e-59 Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG) [Cleaved into: Endorepellin; LG3 peptide] Mus musculus (Mouse) angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; brain development [GO:0007420]; cardiac muscle tissue development [GO:0048738]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; chondrocyte differentiation [GO:0002062]; embryonic skeletal system morphogenesis [GO:0048704]; endochondral ossification [GO:0001958]; extracellular matrix organization [GO:0030198]; negative regulation of amyloid fibril formation [GO:1905907]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell death [GO:0060548]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of endothelial cell proliferation [GO:0001938]; protein localization [GO:0008104]; receptor-mediated endocytosis [GO:0006898]; smoothened signaling pathway [GO:0007224]; tissue development [GO:0009888] GO:0001525; GO:0001938; GO:0001958; GO:0002020; GO:0002062; GO:0005509; GO:0005576; GO:0005604; GO:0005796; GO:0006898; GO:0007162; GO:0007224; GO:0007420; GO:0008022; GO:0008104; GO:0008285; GO:0009887; GO:0009888; GO:0030198; GO:0031012; GO:0048704; GO:0048738; GO:0060351; GO:0060548; GO:0062023; GO:0070052; GO:1905907 34506 XM_029355405.2 432 31 266 400 524 Q05793 6.1e-33 Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG) [Cleaved into: Endorepellin; LG3 peptide] Mus musculus (Mouse) angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; brain development [GO:0007420]; cardiac muscle tissue development [GO:0048738]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; chondrocyte differentiation [GO:0002062]; embryonic skeletal system morphogenesis [GO:0048704]; endochondral ossification [GO:0001958]; extracellular matrix organization [GO:0030198]; negative regulation of amyloid fibril formation [GO:1905907]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell death [GO:0060548]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of endothelial cell proliferation [GO:0001938]; protein localization [GO:0008104]; receptor-mediated endocytosis [GO:0006898]; smoothened signaling pathway [GO:0007224]; tissue development [GO:0009888] GO:0001525; GO:0001938; GO:0001958; GO:0002020; GO:0002062; GO:0005509; GO:0005576; GO:0005604; GO:0005796; GO:0006898; GO:0007162; GO:0007224; GO:0007420; GO:0008022; GO:0008104; GO:0008285; GO:0009887; GO:0009888; GO:0030198; GO:0031012; GO:0048704; GO:0048738; GO:0060351; GO:0060548; GO:0062023; GO:0070052; GO:1905907 34507 XM_029341462.2 49 94 57 65 93 NA NA NA NA NA NA 34508 XM_029340402.2 8919 9030 4313 6836 4709 Q5ZKN1 0 Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 9) Gallus gallus (Chicken) positive regulation of protein localization to chromatin [GO:0120187]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; protein phosphorylation [GO:0006468]; transcription by RNA polymerase II [GO:0006366] GO:0004674; GO:0004693; GO:0005524; GO:0005634; GO:0006366; GO:0006468; GO:0008353; GO:0016592; GO:0032968; GO:0045944; GO:0070691; GO:0106310; GO:0120187 34509 XM_029330997.2 107 52 41 207 155 NA NA NA NA NA NA 34510 XM_044313693.1 3 20 3 50 0 NA NA NA NA NA NA 34511 XR_006391538.1 0 0 0 0 18 NA NA NA NA NA NA 34512 XM_044322653.1 0 0 0 0 6 NA NA NA NA NA NA 34513 XR_006394945.1 1 0 0 6 0 NA NA NA NA NA NA 34514 XM_044318634.1 94 316 27 665 234 NA NA NA NA NA NA 34515 XM_029343545.2 61 75 36 69 36 NA NA NA NA NA NA 34516 XM_029349409.2 2727 1524 996 1394 1712 Q2TA03 2.6e-105 Ubiquitin-conjugating enzyme E2 J2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme J2) Bos taurus (Bovine) protein polyubiquitination [GO:0000209]; response to unfolded protein [GO:0006986]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0000151; GO:0000209; GO:0005524; GO:0005634; GO:0005783; GO:0005789; GO:0006986; GO:0030433; GO:0031625; GO:0061631 34517 XM_029348591.2 166 154 69 160 261 Q9DEY9 9.19e-177 RecQ-like DNA helicase BLM (EC 3.6.4.12) (Bloom syndrome protein homolog) (xBLM) (RecQ helicase homolog) Xenopus laevis (African clawed frog) DNA double-strand break processing [GO:0000729]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA replication [GO:0006260]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of DNA-templated DNA replication [GO:0090329] GO:0000400; GO:0000729; GO:0003677; GO:0003678; GO:0003697; GO:0005524; GO:0005634; GO:0006260; GO:0006310; GO:0008094; GO:0008270; GO:0009378; GO:0016887; GO:0032508; GO:0042803; GO:0043138; GO:0051259; GO:0051260; GO:0061749; GO:0090329 34518 XM_044328004.1 69 13 51 61 223 NA NA NA NA NA NA 34519 XM_044311204.1 2265 1882 1489 2627 2231 A0JP85 0 CCR4-NOT transcription complex subunit 1 (CCR4-associated factor 1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of retinoic acid receptor signaling pathway [GO:0048387]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of translation [GO:0017148]; positive regulation of cytoplasmic mRNA processing body assembly [GO:0010606]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; RNA-mediated gene silencing [GO:0031047] GO:0000122; GO:0000932; GO:0005634; GO:0010606; GO:0017148; GO:0030014; GO:0030015; GO:0030331; GO:0031047; GO:0033147; GO:0042974; GO:0048387; GO:0060213; GO:1900153 34520 XM_044311204.1 2265 1882 1489 2627 2231 A0JP85 0 CCR4-NOT transcription complex subunit 1 (CCR4-associated factor 1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of retinoic acid receptor signaling pathway [GO:0048387]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of translation [GO:0017148]; positive regulation of cytoplasmic mRNA processing body assembly [GO:0010606]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; RNA-mediated gene silencing [GO:0031047] GO:0000122; GO:0000932; GO:0005634; GO:0010606; GO:0017148; GO:0030014; GO:0030015; GO:0030331; GO:0031047; GO:0033147; GO:0042974; GO:0048387; GO:0060213; GO:1900153 34521 XR_006391808.1 0 3 0 10 0 NA NA NA NA NA NA 34522 XM_029337325.2 9 3 10 4 19 P41340 0 Actin-3 (EC 3.6.4.-) Limulus polyphemus (Atlantic horseshoe crab) NA GO:0005524; GO:0005737; GO:0005856; GO:0016787 34523 XM_044321225.1 497 47 390 160 322 P22304 2.71e-177 Iduronate 2-sulfatase (EC 3.1.6.13) (Alpha-L-iduronate sulfate sulfatase) (Idursulfase) [Cleaved into: Iduronate 2-sulfatase 42 kDa chain; Iduronate 2-sulfatase 14 kDa chain] Homo sapiens (Human) dermatan sulfate catabolic process [GO:0030209]; glycosaminoglycan catabolic process [GO:0006027]; heparan sulfate proteoglycan catabolic process [GO:0030200] GO:0004423; GO:0005509; GO:0005737; GO:0005764; GO:0006027; GO:0008484; GO:0030200; GO:0030209; GO:0043202 34524 XM_044310457.1 313 269 83 899 310 Q8R151 0 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 34525 XM_044310457.1 313 269 83 899 310 Q8R151 5.1e-110 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 34526 XM_029330659.2 357 112 141 155 280 NA NA NA NA NA NA 34527 XM_044307384.1 37 17 0 34 21 NA NA NA NA NA NA 34528 XR_006396632.1 0 0 0 0 72 NA NA NA NA NA NA 34529 XM_029353460.2 1303 769 781 956 777 Q9H8M5 2.4e-170 Metal transporter CNNM2 (Ancient conserved domain-containing protein 2) (Cyclin-M2) Homo sapiens (Human) magnesium ion homeostasis [GO:0010960] GO:0005524; GO:0005886; GO:0010960; GO:0015095; GO:0016323; GO:0022857; GO:0043231 34530 XM_029357610.2 176 304 164 303 410 Q5TJE1 1.21e-30 Death domain-associated protein 6 (Daxx) Canis lupus familiaris (Dog) (Canis familiaris) androgen receptor signaling pathway [GO:0030521]; cellular response to cadmium ion [GO:0071276]; cellular response to copper ion [GO:0071280]; cellular response to diamide [GO:0072738]; cellular response to heat [GO:0034605]; cellular response to sodium arsenite [GO:1903936]; cellular response to unfolded protein [GO:0034620]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; JNK cascade [GO:0007254]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; nucleosome assembly [GO:0006334]; positive regulation of neuron death [GO:1901216]; positive regulation of protein kinase activity [GO:0045860]; regulation of apoptotic process [GO:0042981]; regulation of protein ubiquitination [GO:0031396] GO:0000775; GO:0002039; GO:0003713; GO:0003714; GO:0005634; GO:0005730; GO:0005829; GO:0006334; GO:0007254; GO:0008625; GO:0010629; GO:0016605; GO:0019901; GO:0030295; GO:0030521; GO:0031396; GO:0031625; GO:0034605; GO:0034620; GO:0042393; GO:0042803; GO:0042981; GO:0045860; GO:0045892; GO:0047485; GO:0050681; GO:0061629; GO:0071276; GO:0071280; GO:0072738; GO:0140037; GO:0140416; GO:1901216; GO:1903936 34531 XM_029342872.2 17 0 4 0 70 NA NA NA NA NA NA 34532 XM_044310564.1 58 94 98 218 229 NA NA NA NA NA NA 34533 XR_006393768.1 29 34 56 30 35 NA NA NA NA NA NA 34534 XM_029331308.2 0 17 26 49 8 NA NA NA NA NA NA 34535 XM_044320975.1 10 10 26 71 14 NA NA NA NA NA NA 34536 XM_044320303.1 108 60 35 47 65 NA NA NA NA NA NA 34537 XM_029335339.2 460 477 390 628 623 NA NA NA NA NA NA 34538 XR_006396246.1 3 0 19 12 18 NA NA NA NA NA NA 34539 XM_044318576.1 0 0 70 111 0 Q68F72 2.95e-92 Solute carrier family 15 member 4 Xenopus laevis (African clawed frog) dipeptide import across plasma membrane [GO:0140206]; innate immune response [GO:0045087]; mast cell homeostasis [GO:0033023]; peptidoglycan transport [GO:0015835]; positive regulation of innate immune response [GO:0045089]; positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [GO:0070430]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of toll-like receptor 7 signaling pathway [GO:0034157]; positive regulation of toll-like receptor 8 signaling pathway [GO:0034161]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; protein transport [GO:0015031]; regulation of isotype switching to IgG isotypes [GO:0048302]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424] GO:0005290; GO:0005765; GO:0015031; GO:0015333; GO:0015647; GO:0015835; GO:0031901; GO:0033023; GO:0034157; GO:0034161; GO:0034165; GO:0036020; GO:0045087; GO:0045089; GO:0048302; GO:0070424; GO:0070430; GO:0070434; GO:0071916; GO:0140206 34540 XR_006391432.1 0 0 0 8 1 NA NA NA NA NA NA 34541 XM_029335564.2 0 114 57 222 0 NA NA NA NA NA NA 34542 XM_044311468.1 264 200 208 109 709 NA NA NA NA NA NA 34543 XM_029337854.2 777 354 377 643 531 Q6NSI8 2.86e-132 SANT and BTB domain regulator of class switch recombination (SANT and BTB domain regulator of CSR) Homo sapiens (Human) isotype switching [GO:0045190] GO:0042802; GO:0045190 34544 XM_044307669.1 0 0 8 4 4 Q62371 1.08e-37 Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b) Mus musculus (Mouse) biomineral tissue development [GO:0031214]; cellular response to angiotensin [GO:1904385]; cellular response to hypoxia [GO:0071456]; cellular response to transforming growth factor beta stimulus [GO:0071560]; chondrocyte proliferation [GO:0035988]; collagen fibril organization [GO:0030199]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; endochondral bone growth [GO:0003416]; negative regulation of apoptotic process [GO:0043066]; negative regulation of hydrogen peroxide-mediated programmed cell death [GO:1901299]; negative regulation of kinase activity [GO:0033673]; negative regulation of necrotic cell death [GO:0060547]; ossification [GO:0001503]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of hepatic stellate cell activation [GO:2000491]; positive regulation of hepatic stellate cell proliferation [GO:1904899]; positive regulation of kinase activity [GO:0033674]; positive regulation of neuron death [GO:1901216]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; positive regulation of vascular associated smooth muscle cell proliferation [GO:1904707]; positive regulation of wound healing [GO:0090303]; protein autophosphorylation [GO:0046777]; regulation of bone mineralization [GO:0030500]; regulation of tissue remodeling [GO:0034103]; response to muscle stretch [GO:0035994]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0001503; GO:0003416; GO:0004714; GO:0005518; GO:0005524; GO:0005886; GO:0007169; GO:0008284; GO:0010763; GO:0015629; GO:0016324; GO:0018108; GO:0030199; GO:0030500; GO:0031214; GO:0032967; GO:0033673; GO:0033674; GO:0034103; GO:0035988; GO:0035994; GO:0038062; GO:0038063; GO:0043066; GO:0043235; GO:0045669; GO:0045860; GO:0046777; GO:0048146; GO:0051091; GO:0060547; GO:0070374; GO:0071456; GO:0071560; GO:0090091; GO:0090303; GO:1900087; GO:1901216; GO:1901299; GO:1904385; GO:1904707; GO:1904754; GO:1904899; GO:2000491 34545 XM_044320430.1 418 450 108 368 60 NA NA NA NA NA NA 34546 XM_044317704.1 341 237 440 577 517 Q0VGW6 7.55e-146 Solute carrier family 12 member 9 (Cation-chloride cotransporter-interacting protein 1) Xenopus laevis (African clawed frog) NA GO:0005886; GO:0015377 34547 XM_044313177.1 30 22 25 53 61 NA NA NA NA NA NA 34548 XM_044323838.1 2 3 14 0 70 NA NA NA NA NA NA 34549 XM_044309851.1 32 6 2 52 545 NA NA NA NA NA NA 34550 XM_029331906.2 55 49 31 31 77 NA NA NA NA NA NA 34551 XR_003823073.2 12 7 2 6 28 NA NA NA NA NA NA 34552 XM_044314885.1 218 398 146 24 125 Q9JHX4 4.27e-29 Caspase-8 (CASP-8) (EC 3.4.22.61) [Cleaved into: Caspase-8 subunit p18; Caspase-8 subunit p10] Rattus norvegicus (Rat) activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; execution phase of apoptosis [GO:0097194]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; heart development [GO:0007507]; hepatocyte apoptotic process [GO:0097284]; macrophage differentiation [GO:0030225]; necroptotic process [GO:0070266]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of necroptotic process [GO:0060546]; neural tube formation [GO:0001841]; positive regulation of apoptotic process [GO:0043065]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of neuron death [GO:1901216]; positive regulation of proteolysis [GO:0045862]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; pyroptosis [GO:0070269]; regulation of apoptotic signaling pathway [GO:2001233]; regulation of cytokine production [GO:0001817]; regulation of innate immune response [GO:0045088]; regulation of thymocyte apoptotic process [GO:0070243]; response to antibiotic [GO:0046677]; response to cobalt ion [GO:0032025]; response to cold [GO:0009409]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]; self proteolysis [GO:0097264]; TRAIL-activated apoptotic signaling pathway [GO:0036462] GO:0001525; GO:0001817; GO:0001841; GO:0004175; GO:0004197; GO:0005123; GO:0005164; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0006508; GO:0006915; GO:0006919; GO:0007507; GO:0008233; GO:0008303; GO:0008625; GO:0009409; GO:0016485; GO:0030225; GO:0030690; GO:0031264; GO:0031265; GO:0031625; GO:0032025; GO:0032355; GO:0032496; GO:0032731; GO:0032991; GO:0034612; GO:0035877; GO:0036462; GO:0042802; GO:0043005; GO:0043065; GO:0043123; GO:0043124; GO:0044297; GO:0044877; GO:0045088; GO:0045121; GO:0045471; GO:0045651; GO:0045862; GO:0046677; GO:0051603; GO:0060546; GO:0070243; GO:0070266; GO:0070269; GO:0071260; GO:0071407; GO:0097110; GO:0097153; GO:0097190; GO:0097191; GO:0097194; GO:0097199; GO:0097200; GO:0097202; GO:0097264; GO:0097284; GO:0097342; GO:1901216; GO:2001233; GO:2001238 34553 XM_029339944.2 766 305 357 53 331 Q9UJT0 0 Tubulin epsilon chain (Epsilon-tubulin) Homo sapiens (Human) centrosome cycle [GO:0007098]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278] GO:0000226; GO:0000242; GO:0000278; GO:0005200; GO:0005525; GO:0005737; GO:0005874; GO:0007098 34554 XM_029347461.2 487 244 247 414 453 NA NA NA NA NA NA 34555 XM_029335928.2 2002 2482 2299 2192 1754 P83871 2.73e-68 PHD finger-like domain-containing protein 5A (PHD finger-like domain protein 5A) (Splicing factor 3B-associated 14 kDa protein) (SF3b14b) Rattus norvegicus (Rat) mRNA splicing, via spliceosome [GO:0000398]; positive regulation of DNA-templated transcription [GO:0045893]; stem cell differentiation [GO:0048863] GO:0000398; GO:0003677; GO:0003723; GO:0005634; GO:0005684; GO:0005686; GO:0005689; GO:0008270; GO:0016363; GO:0016607; GO:0045893; GO:0048863; GO:0071005; GO:0071011 34556 XR_003825830.2 59 0 0 0 17 NA NA NA NA NA NA 34557 XR_003828249.2 487 26 58 35 131 NA NA NA NA NA NA 34558 XM_044310003.1 210 37 0 27 0 O54697 5.75e-123 Aminopeptidase NAALADL1 (EC 3.4.11.-) (100 kDa ileum brush border membrane protein) (I100) (Ileal dipeptidylpeptidase) (N-acetylated-alpha-linked acidic dipeptidase-like protein) (NAALADase L) Rattus norvegicus (Rat) peptide catabolic process [GO:0043171]; proteolysis [GO:0006508] GO:0004177; GO:0004180; GO:0005509; GO:0006508; GO:0008237; GO:0008270; GO:0016020; GO:0016324; GO:0042803; GO:0043171 34559 XM_044323196.1 0 0 0 0 19 O73792 7.81e-53 Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1) Danio rerio (Zebrafish) (Brachydanio rerio) angiogenesis [GO:0001525]; blood vessel development [GO:0001568]; endothelial cell-cell adhesion [GO:0071603]; heart development [GO:0007507]; positive regulation of angiogenesis [GO:0045766]; positive regulation of kinase activity [GO:0033674]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculature development [GO:0001944] GO:0001525; GO:0001568; GO:0001944; GO:0004714; GO:0005524; GO:0005886; GO:0007169; GO:0007507; GO:0033674; GO:0043235; GO:0045766; GO:0071603 34560 XM_044320364.1 6 3 6 6 8 Q8TE73 3.01e-33 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5) Homo sapiens (Human) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0005524; GO:0005576; GO:0005737; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 34561 XM_044314452.1 1665 989 512 856 991 O75840 6.76e-49 Krueppel-like factor 7 (Ubiquitous krueppel-like factor) Homo sapiens (Human) axon guidance [GO:0007411]; axonogenesis [GO:0007409]; dendrite morphogenesis [GO:0048813]; glucose homeostasis [GO:0042593]; negative regulation of adipose tissue development [GO:1904178]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of epidermal cell differentiation [GO:0045604]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000785; GO:0000978; GO:0000981; GO:0001228; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0007409; GO:0007411; GO:0008270; GO:0042593; GO:0045604; GO:0045944; GO:0048813; GO:0061179; GO:1904178 34562 XM_044321504.1 0 0 10 0 19 NA NA NA NA NA NA 34563 XM_029354478.2 367 104 69 110 80 A4IGM4 9.95e-59 Hydroxysteroid 11-beta-dehydrogenase 1-like protein (EC 1.1.1.-) (11-beta-hydroxysteroid dehydrogenase type 3) (11-DH3) (11-beta-HSD3) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005576; GO:0016491 34564 XM_029342607.2 23 0 0 23 0 Q9VBW3 4.73e-85 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 34565 XM_044325691.1 2 0 12 21 6 NA NA NA NA NA NA 34566 XM_029329444.2 69 236 51 142 320 O94818 3.86e-35 Nucleolar protein 4 (Nucleolar-localized protein) Homo sapiens (Human) NA GO:0003723; GO:0005730 34567 XM_029329444.2 69 236 51 142 320 O94818 3.58e-27 Nucleolar protein 4 (Nucleolar-localized protein) Homo sapiens (Human) NA GO:0003723; GO:0005730 34568 XM_029342328.2 205 142 399 78 466 NA NA NA NA NA NA 34569 XR_006393154.1 193 338 236 327 168 NA NA NA NA NA NA 34570 XM_044326417.1 1570 893 1296 1173 1475 Q9UP83 0 Conserved oligomeric Golgi complex subunit 5 (COG complex subunit 5) (13S Golgi transport complex 90 kDa subunit) (GTC-90) (Component of oligomeric Golgi complex 5) (Golgi transport complex 1) Homo sapiens (Human) glycosylation [GO:0070085]; Golgi organization [GO:0007030]; inter-Golgi cisterna vesicle-mediated transport [GO:0048219]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein transport [GO:0015031]; retrograde transport, vesicle recycling within Golgi [GO:0000301] GO:0000139; GO:0000301; GO:0005654; GO:0005794; GO:0005829; GO:0006891; GO:0007030; GO:0015031; GO:0016020; GO:0017119; GO:0032588; GO:0048219; GO:0070085 34571 XM_029356851.2 250 182 146 265 202 NA NA NA NA NA NA 34572 XR_006397121.1 11 0 0 19 43 NA NA NA NA NA NA 34573 XM_029351708.2 30 56 23 65 98 Q8VIG6 1.29e-31 E3 ubiquitin-protein ligase TRAIP (EC 2.3.2.27) (TRAF-interacting protein) Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; protein ubiquitination [GO:0016567]; protein-DNA covalent cross-linking repair [GO:0106300]; replication fork processing [GO:0031297]; signal transduction [GO:0007165] GO:0004842; GO:0005634; GO:0005654; GO:0005730; GO:0006974; GO:0007165; GO:0010804; GO:0016567; GO:0031297; GO:0032088; GO:0032688; GO:0042802; GO:0046872; GO:0048471; GO:0061630; GO:0090734; GO:0106300 34574 XM_029330727.2 1726 1200 1237 3403 1845 O15063 1.11e-30 Granule associated Rac and RHOG effector protein 1 (GARRE1) Homo sapiens (Human) Rac protein signal transduction [GO:0016601] GO:0000932; GO:0005829; GO:0016601; GO:0031267; GO:1905762 34575 XR_003824378.2 149 1143 73 71 73 NA NA NA NA NA NA 34576 XM_044317627.1 0 38 0 0 0 Q5RHH4 0 Intraflagellar transport protein 172 homolog Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; intraciliary transport [GO:0042073]; photoreceptor cell maintenance [GO:0045494]; pronephros development [GO:0048793]; regulation of TOR signaling [GO:0032006]; retina development in camera-type eye [GO:0060041] GO:0005929; GO:0005930; GO:0030992; GO:0032006; GO:0036064; GO:0042073; GO:0045494; GO:0048793; GO:0060041; GO:0060271 34577 XM_044314445.1 91 49 2 83 22 NA NA NA NA NA NA 34578 XM_029351823.2 0 46 0 36 0 Q9NYT0 6.51e-48 Pleckstrin-2 Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; intracellular signal transduction [GO:0035556]; positive regulation of plasma membrane bounded cell projection assembly [GO:0120034] GO:0005737; GO:0005856; GO:0005886; GO:0031258; GO:0031532; GO:0032266; GO:0035556; GO:0043325; GO:0080025; GO:0120034 34579 XM_029354939.2 14 0 14 9 9 NA NA NA NA NA NA 34580 XM_029357001.2 551 429 457 754 1567 Q3T1L0 0 Aldehyde dehydrogenase family 16 member A1 Rattus norvegicus (Rat) NA GO:0016620 34581 XM_029332771.2 831 642 411 910 740 NA NA NA NA NA NA 34582 XM_044312706.1 0 0 0 7 7 NA NA NA NA NA NA 34583 XM_044320466.1 2436 1895 1758 1467 3430 P48722 0 Heat shock 70 kDa protein 4L (Heat shock 70-related protein APG-1) (Osmotic stress protein 94) Mus musculus (Mouse) protein folding [GO:0006457]; response to unfolded protein [GO:0006986] GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006457; GO:0006986; GO:0140662 34584 XM_029333787.2 20 33 30 25 87 Q91ZY8 1.54e-76 E3 ubiquitin-protein ligase TRIM9 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TRIM9) (SNAP-25-interacting RING finger protein) (Tripartite motif-containing protein 9) Rattus norvegicus (Rat) negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of SNARE complex assembly [GO:0035544]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; synaptic vesicle exocytosis [GO:0016079] GO:0000149; GO:0005737; GO:0005856; GO:0008021; GO:0008270; GO:0016079; GO:0019904; GO:0030425; GO:0035544; GO:0042803; GO:0043161; GO:0045955; GO:0061630; GO:0099523 34585 XM_029333787.2 20 33 30 25 87 Q91ZY8 1.35e-23 E3 ubiquitin-protein ligase TRIM9 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TRIM9) (SNAP-25-interacting RING finger protein) (Tripartite motif-containing protein 9) Rattus norvegicus (Rat) negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of SNARE complex assembly [GO:0035544]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; synaptic vesicle exocytosis [GO:0016079] GO:0000149; GO:0005737; GO:0005856; GO:0008021; GO:0008270; GO:0016079; GO:0019904; GO:0030425; GO:0035544; GO:0042803; GO:0043161; GO:0045955; GO:0061630; GO:0099523 34586 XM_029348925.2 51 0 10 0 0 Q6P360 7.77e-92 E3 ubiquitin ligase Rnf121 (EC 2.3.2.27) (RING finger protein 121) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0016020; GO:0046872 34587 XM_029354223.2 0 61 10 24 0 NA NA NA NA NA NA 34588 XM_044325016.1 10 1 0 13 20 NA NA NA NA NA NA 34589 XR_006392993.1 41 2 25 5 151 NA NA NA NA NA NA 34590 XR_006397674.1 59 5 32 17 85 NA NA NA NA NA NA 34591 XR_006392628.1 0 0 1 0 22 NA NA NA NA NA NA 34592 XM_044324914.1 285 516 281 270 165 Q8VBV3 1.19e-123 Exosome complex component RRP4 (Exosome component 2) (Ribosomal RNA-processing protein 4) Mus musculus (Mouse) CUT catabolic process [GO:0071034]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; positive regulation of cell growth [GO:0030307]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]; U4 snRNA 3'-end processing [GO:0034475] GO:0000176; GO:0000177; GO:0000178; GO:0000467; GO:0003723; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0006396; GO:0006401; GO:0030307; GO:0034427; GO:0034475; GO:0043928; GO:0071034; GO:0071035; GO:0071038; GO:0071051; GO:0101019 34593 XM_044308513.1 0 3 31 1 59 NA NA NA NA NA NA 34594 XM_044321644.1 6 32 13 0 11 NA NA NA NA NA NA 34595 XM_029341214.2 4276 3790 3184 4392 4043 C4R7Z3 5.71e-128 Sphingolipid C9-methyltransferase (C-9-MT) (EC 2.1.1.317) Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris) methylation [GO:0032259]; sphingolipid metabolic process [GO:0006665] GO:0006665; GO:0008168; GO:0016020; GO:0032259 34596 XM_029353883.2 0 0 18 0 5 P82649 2.06e-86 28S ribosomal protein S22, mitochondrial (MRP-S22) (S22mt) Bos taurus (Bovine) mitochondrial translation [GO:0032543] GO:0003735; GO:0005743; GO:0005763; GO:0032543 34597 XM_029347952.2 27 21 19 35 41 B3DM66 3.03e-35 G-protein coupled receptor 161 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:1901621] GO:0004930; GO:0005929; GO:0007189; GO:0055037; GO:0060170; GO:1901621 34598 XM_029335346.2 0 98 103 235 194 Q7SY06 2.39e-74 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase (EC 4.2.1.134) (3-hydroxyacyl-CoA dehydratase) (HACD) (Protein-tyrosine phosphatase-like A domain-containing protein 1) Danio rerio (Zebrafish) (Brachydanio rerio) fatty acid elongation [GO:0030497]; sphingolipid biosynthetic process [GO:0030148]; very long-chain fatty acid biosynthetic process [GO:0042761] GO:0005783; GO:0005789; GO:0018812; GO:0030148; GO:0030497; GO:0042761; GO:0102158; GO:0102343; GO:0102344; GO:0102345 34599 XM_029330351.2 0 0 9 1 1 Q5F4A1 8.22e-24 G2/M phase-specific E3 ubiquitin-protein ligase (EC 2.3.2.26) (G2/M phase-specific HECT-type E3 ubiquitin transferase) Gallus gallus (Chicken) apoptotic process [GO:0006915] GO:0004842; GO:0005634; GO:0005730; GO:0005737; GO:0006915; GO:0046872 34600 XM_044319938.1 139 0 113 12 16 NA NA NA NA NA NA 34601 XM_029340739.2 73 31 35 35 60 Q7L5Y6 0 DET1 homolog (De-etiolated-1 homolog) Homo sapiens (Human) positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein ubiquitination [GO:0016567]; protein-containing complex assembly [GO:0065003] GO:0005634; GO:0016567; GO:0031461; GO:0031464; GO:0031625; GO:0032436; GO:0044877; GO:0065003; GO:0080008; GO:1990756 34602 XM_044325408.1 0 177 0 172 0 Q9DBN1 3.3e-29 Stimulated by retinoic acid gene 6 protein-like (STRA6-like protein) (Retinol-binding protein 4 receptor 2) (RBP4 receptor 2) Mus musculus (Mouse) establishment of localization in cell [GO:0051649]; retinol transport [GO:0034633]; vitamin A import into cell [GO:0071939] GO:0005886; GO:0034633; GO:0051649; GO:0071939 34603 XR_006391994.1 3 0 6 2 60 NA NA NA NA NA NA 34604 XM_029329833.2 434 683 364 452 273 NA NA NA NA NA NA 34605 XM_044308603.1 195 107 239 341 622 Q9U943 1.37e-56 Apolipophorins [Cleaved into: Apolipophorin-2 (Apolipophorin II) (apoLp-2); Apolipophorin-1 (Apolipophorin I) (apoLp-1)] Locusta migratoria (Migratory locust) Wnt signaling pathway [GO:0016055] GO:0005319; GO:0005576; GO:0008289; GO:0016055 34606 XR_006394357.1 31 21 77 28 64 NA NA NA NA NA NA 34607 XM_044320664.1 4 4 0 0 40 Q6ZWJ1 3.88e-33 Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (STX4-interacting protein) (Synip) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; cellular response to type II interferon [GO:0071346]; insulin receptor signaling pathway [GO:0008286]; positive regulation of cell cycle G1/S phase transition [GO:1902808]; positive regulation of keratinocyte proliferation [GO:0010838]; protein stabilization [GO:0050821]; protein targeting [GO:0006605]; regulation of glucose transmembrane transport [GO:0010827]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072] GO:0006605; GO:0006974; GO:0008286; GO:0010827; GO:0010838; GO:0019905; GO:0031410; GO:0045335; GO:0050821; GO:0061178; GO:0070062; GO:0071346; GO:0098685; GO:0099072; GO:1902808 34608 XR_006397942.1 1216 647 716 1029 938 P16065 0 Speract receptor (EC 4.6.1.2) (Guanylate cyclase) Strongylocentrotus purpuratus (Purple sea urchin) cGMP biosynthetic process [GO:0006182]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]; receptor guanylyl cyclase signaling pathway [GO:0007168]; signal transduction [GO:0007165] GO:0001653; GO:0004383; GO:0004672; GO:0005524; GO:0005525; GO:0005886; GO:0006182; GO:0006468; GO:0007165; GO:0007168; GO:0035556 34609 XR_006397942.1 1216 647 716 1029 938 P16065 0 Speract receptor (EC 4.6.1.2) (Guanylate cyclase) Strongylocentrotus purpuratus (Purple sea urchin) cGMP biosynthetic process [GO:0006182]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]; receptor guanylyl cyclase signaling pathway [GO:0007168]; signal transduction [GO:0007165] GO:0001653; GO:0004383; GO:0004672; GO:0005524; GO:0005525; GO:0005886; GO:0006182; GO:0006468; GO:0007165; GO:0007168; GO:0035556 34610 XM_044328576.1 0 0 0 71 6 NA NA NA NA NA NA 34611 XM_044310821.1 7 0 6 17 0 NA NA NA NA NA NA 34612 XM_044319553.1 64 55 29 71 73 NA NA NA NA NA NA 34613 XM_029326468.2 109 1868 0 2431 2263 P61765 0 Syntaxin-binding protein 1 (N-Sec1) (Protein unc-18 homolog 1) (Unc18-1) (Protein unc-18 homolog A) (Unc-18A) (p67) (rbSec1) Rattus norvegicus (Rat) axon target recognition [GO:0007412]; cellular response to type II interferon [GO:0071346]; developmental process involved in reproduction [GO:0003006]; establishment of localization in cell [GO:0051649]; exocytosis [GO:0006887]; intracellular protein transport [GO:0006886]; long-term synaptic depression [GO:0060292]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of SNARE complex assembly [GO:0035544]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; neuromuscular synaptic transmission [GO:0007274]; neuron apoptotic process [GO:0051402]; neurotransmitter secretion [GO:0007269]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of exocytosis [GO:0045921]; positive regulation of glutamate secretion, neurotransmission [GO:1903296]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of vesicle docking [GO:0106022]; presynaptic dense core vesicle exocytosis [GO:0099525]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; regulation of acrosomal vesicle exocytosis [GO:2000367]; regulation of synaptic vesicle priming [GO:0010807]; regulation of vesicle fusion [GO:0031338]; response to estradiol [GO:0032355]; SNARE complex assembly [GO:0035493]; synaptic vesicle maturation [GO:0016188]; synaptic vesicle priming [GO:0016082]; vesicle docking involved in exocytosis [GO:0006904]; vesicle-mediated transport [GO:0016192] GO:0000149; GO:0002576; GO:0003006; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0006886; GO:0006887; GO:0006904; GO:0007269; GO:0007274; GO:0007412; GO:0010807; GO:0016082; GO:0016188; GO:0016192; GO:0017075; GO:0019901; GO:0019904; GO:0019905; GO:0030141; GO:0030424; GO:0031091; GO:0031333; GO:0031338; GO:0032229; GO:0032355; GO:0032991; GO:0035493; GO:0035544; GO:0042802; GO:0043195; GO:0043274; GO:0043306; GO:0043524; GO:0045335; GO:0045921; GO:0045956; GO:0047485; GO:0048471; GO:0048787; GO:0050821; GO:0051402; GO:0051649; GO:0060090; GO:0060292; GO:0070527; GO:0071346; GO:0072659; GO:0098688; GO:0098793; GO:0098794; GO:0098831; GO:0098888; GO:0098978; GO:0099523; GO:0099525; GO:0106022; GO:1903296; GO:2000367 34614 XM_044315806.1 16 1 23 10 51 NA NA NA NA NA NA 34615 XM_044323839.1 123 55 14 305 84 NA NA NA NA NA NA 34616 XM_044326645.1 1214 1949 877 1212 1156 A7RT29 1.71e-43 Ragulator complex protein LAMTOR5 homolog (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5) Nematostella vectensis (Starlet sea anemone) cellular response to amino acid stimulus [GO:0071230]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of TOR signaling [GO:0032008]; positive regulation of TORC1 signaling [GO:1904263]; protein localization to lysosome [GO:0061462]; regulation of cell size [GO:0008361] GO:0005764; GO:0008361; GO:0032008; GO:0043154; GO:0061462; GO:0071230; GO:0071986; GO:1904263 34617 XM_029347915.2 1782 1326 970 1338 1100 Q9VCA9 1.22e-65 Signal peptidase complex subunit 3 (Microsomal signal peptidase 22 kDa subunit) (SPC22) (SPase 22 kDa subunit) Drosophila melanogaster (Fruit fly) protein targeting to ER [GO:0045047]; signal peptide processing [GO:0006465] GO:0005787; GO:0006465; GO:0045047 34618 XR_006393072.1 41 2 25 5 151 NA NA NA NA NA NA 34619 XM_044313495.1 2868 2082 1286 2582 1492 Q9D051 0 Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (PDHE1-B) (EC 1.2.4.1) Mus musculus (Mouse) acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; tricarboxylic acid cycle [GO:0006099] GO:0004739; GO:0005654; GO:0005739; GO:0005967; GO:0006006; GO:0006086; GO:0006099; GO:0034604; GO:0045240; GO:0045254; GO:1902493; GO:1902494 34620 XM_044316375.1 0 1 383 258 237 NA NA NA NA NA NA 34621 XM_029351110.2 6 91 46 0 0 NA NA NA NA NA NA 34622 XM_029340981.2 314 211 210 226 368 Q9EP71 4.61e-38 Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Novel retinal pigment epithelial cell protein) (Retinoic acid-induced protein 14) (p125) Mus musculus (Mouse) cell differentiation [GO:0030154]; spermatogenesis [GO:0007283] GO:0001650; GO:0003779; GO:0005654; GO:0005739; GO:0005829; GO:0005856; GO:0005938; GO:0007283; GO:0030154; GO:0070161 34623 XM_029333671.2 136 107 85 157 193 Q6NU91 8.1e-129 Nucleolar complex protein 4 homolog B (NOC4 protein homolog B) (NOC4-like protein B) (Nucleolar complex-associated protein 4-like protein B) Xenopus laevis (African clawed frog) ribosome biogenesis [GO:0042254] GO:0005730; GO:0031965; GO:0042254 34624 XM_044328593.1 260 402 159 242 161 NA NA NA NA NA NA 34625 XM_029328903.2 1116 963 28 0 71 Q28DB0 3.96e-121 Tetratricopeptide repeat protein 39B (TPR repeat protein 39B) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) lipid metabolic process [GO:0006629] GO:0006629 34626 XM_044326579.1 0 13 0 0 0 Q09575 9.39e-63 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 34627 XM_044325969.1 1 0 0 0 9 NA NA NA NA NA NA 34628 XM_044315548.1 5 0 18 11 86 NA NA NA NA NA NA 34629 XM_029347874.2 206 95 151 113 182 Q3LSS0 1.07e-152 CWF19-like protein 2 Danio rerio (Zebrafish) (Brachydanio rerio) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0071014 34630 XM_044323188.1 6 0 12 1 34 NA NA NA NA NA NA 34631 XM_029333419.2 207 258 194 250 382 Q06609 0 DNA repair protein RAD51 homolog 1 (HsRAD51) (hRAD51) (RAD51 homolog A) Homo sapiens (Human) cellular response to camptothecin [GO:0072757]; cellular response to cisplatin [GO:0072719]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; cellular response to hydroxyurea [GO:0072711]; cellular response to ionizing radiation [GO:0071479]; chromosome organization involved in meiotic cell cycle [GO:0070192]; DNA recombinase assembly [GO:0000730]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724]; histone H2A monoubiquitination [GO:0035518]; interstrand cross-link repair [GO:0036297]; meiotic cell cycle [GO:0051321]; mitotic recombination [GO:0006312]; mitotic recombination-dependent replication fork processing [GO:1990426]; positive regulation of DNA ligation [GO:0051106]; protein autoubiquitination [GO:0051865]; reciprocal meiotic recombination [GO:0007131]; regulation of DNA damage checkpoint [GO:2000001]; regulation of double-strand break repair via homologous recombination [GO:0010569]; regulation of protein phosphorylation [GO:0001932]; replication fork processing [GO:0031297]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414]; response to glucoside [GO:1904631]; response to toxic substance [GO:0009636]; response to X-ray [GO:0010165]; response to xenobiotic stimulus [GO:0009410]; strand invasion [GO:0042148]; telomere maintenance via recombination [GO:0000722]; telomere maintenance via telomere lengthening [GO:0010833] GO:0000150; GO:0000152; GO:0000228; GO:0000722; GO:0000724; GO:0000730; GO:0000781; GO:0000785; GO:0000793; GO:0000794; GO:0000800; GO:0001673; GO:0001932; GO:0003676; GO:0003682; GO:0003690; GO:0003697; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005759; GO:0005815; GO:0006268; GO:0006281; GO:0006310; GO:0006312; GO:0006974; GO:0007131; GO:0008022; GO:0008094; GO:0009410; GO:0009636; GO:0010165; GO:0010569; GO:0010833; GO:0016605; GO:0017116; GO:0019899; GO:0031297; GO:0032991; GO:0035518; GO:0035861; GO:0036297; GO:0042148; GO:0042802; GO:0048471; GO:0051106; GO:0051321; GO:0051865; GO:0070182; GO:0070192; GO:0071479; GO:0071480; GO:0072711; GO:0072719; GO:0072757; GO:0140664; GO:1904631; GO:1990414; GO:1990426; GO:2000001 34632 XR_006396984.1 31 17 34 68 69 NA NA NA NA NA NA 34633 XM_044318387.1 0 0 1 4 37 NA NA NA NA NA NA 34634 XM_044329091.1 495 223 293 474 613 A6L330 8.54e-100 Probable endonuclease 4 (EC 3.1.21.2) (Endodeoxyribonuclease IV) (Endonuclease IV) Phocaeicola vulgatus (strain ATCC 8482 / DSM 1447 / JCM 5826 / CCUG 4940 / NBRC 14291 / NCTC 11154) (Bacteroides vulgatus) DNA repair [GO:0006281] GO:0003677; GO:0006281; GO:0008270; GO:0008833 34635 XM_044327993.1 334 128 148 94 136 Q8C8H8 1.31e-29 Kyphoscoliosis peptidase (EC 3.4.-.-) Mus musculus (Mouse) muscle organ development [GO:0007517]; neuromuscular junction development [GO:0007528]; proteolysis [GO:0006508] GO:0005737; GO:0005856; GO:0006508; GO:0007517; GO:0007528; GO:0008233; GO:0030018 34636 XM_044327898.1 886 404 432 604 611 Q9QZ05 0 eIF-2-alpha kinase GCN2 (Eukaryotic translation initiation factor 2-alpha kinase 4) (EC 2.7.11.1) (GCN2-like protein) (mGCN2) Mus musculus (Mouse) adaptive immune response [GO:0002250]; cell cycle [GO:0007049]; cellular response to amino acid starvation [GO:0034198]; cellular response to cold [GO:0070417]; cellular response to leucine starvation [GO:1990253]; cellular response to starvation [GO:0009267]; cellular response to UV [GO:0034644]; defense response to virus [GO:0051607]; DNA damage checkpoint signaling [GO:0000077]; eiF2alpha phosphorylation in response to endoplasmic reticulum stress [GO:0036492]; endoplasmic reticulum unfolded protein response [GO:0030968]; GCN2-mediated signaling [GO:0140469]; learning [GO:0007612]; long-term memory [GO:0007616]; negative regulation by host of viral genome replication [GO:0044828]; negative regulation of CREB transcription factor activity [GO:0032792]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of translation [GO:0017148]; negative regulation of translational initiation [GO:0045947]; negative regulation of translational initiation in response to stress [GO:0032057]; neuron projection extension [GO:1990138]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of gene expression [GO:0010628]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of translational initiation in response to starvation [GO:0071264]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of feeding behavior [GO:0060259]; regulation of translational initiation [GO:0006446]; regulation of translational initiation by eIF2 alpha phosphorylation [GO:0010998]; regulation of translational initiation in response to stress [GO:0043558]; response to endoplasmic reticulum stress [GO:0034976]; T cell activation involved in immune response [GO:0002286]; viral translation [GO:0019081] GO:0000049; GO:0000077; GO:0001934; GO:0002230; GO:0002250; GO:0002286; GO:0002821; GO:0004672; GO:0004674; GO:0004694; GO:0005524; GO:0005829; GO:0005844; GO:0006446; GO:0006468; GO:0007049; GO:0007612; GO:0007616; GO:0009267; GO:0010628; GO:0010998; GO:0017148; GO:0019081; GO:0022626; GO:0030968; GO:0032057; GO:0032792; GO:0034198; GO:0034644; GO:0034976; GO:0036492; GO:0043558; GO:0044828; GO:0045665; GO:0045947; GO:0046777; GO:0051607; GO:0060259; GO:0070417; GO:0071074; GO:0071264; GO:0106310; GO:0140469; GO:1900273; GO:1990138; GO:1990253 34637 XM_044327898.1 886 404 432 604 611 Q9QZ05 1.25e-58 eIF-2-alpha kinase GCN2 (Eukaryotic translation initiation factor 2-alpha kinase 4) (EC 2.7.11.1) (GCN2-like protein) (mGCN2) Mus musculus (Mouse) adaptive immune response [GO:0002250]; cell cycle [GO:0007049]; cellular response to amino acid starvation [GO:0034198]; cellular response to cold [GO:0070417]; cellular response to leucine starvation [GO:1990253]; cellular response to starvation [GO:0009267]; cellular response to UV [GO:0034644]; defense response to virus [GO:0051607]; DNA damage checkpoint signaling [GO:0000077]; eiF2alpha phosphorylation in response to endoplasmic reticulum stress [GO:0036492]; endoplasmic reticulum unfolded protein response [GO:0030968]; GCN2-mediated signaling [GO:0140469]; learning [GO:0007612]; long-term memory [GO:0007616]; negative regulation by host of viral genome replication [GO:0044828]; negative regulation of CREB transcription factor activity [GO:0032792]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of translation [GO:0017148]; negative regulation of translational initiation [GO:0045947]; negative regulation of translational initiation in response to stress [GO:0032057]; neuron projection extension [GO:1990138]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of gene expression [GO:0010628]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of translational initiation in response to starvation [GO:0071264]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of feeding behavior [GO:0060259]; regulation of translational initiation [GO:0006446]; regulation of translational initiation by eIF2 alpha phosphorylation [GO:0010998]; regulation of translational initiation in response to stress [GO:0043558]; response to endoplasmic reticulum stress [GO:0034976]; T cell activation involved in immune response [GO:0002286]; viral translation [GO:0019081] GO:0000049; GO:0000077; GO:0001934; GO:0002230; GO:0002250; GO:0002286; GO:0002821; GO:0004672; GO:0004674; GO:0004694; GO:0005524; GO:0005829; GO:0005844; GO:0006446; GO:0006468; GO:0007049; GO:0007612; GO:0007616; GO:0009267; GO:0010628; GO:0010998; GO:0017148; GO:0019081; GO:0022626; GO:0030968; GO:0032057; GO:0032792; GO:0034198; GO:0034644; GO:0034976; GO:0036492; GO:0043558; GO:0044828; GO:0045665; GO:0045947; GO:0046777; GO:0051607; GO:0060259; GO:0070417; GO:0071074; GO:0071264; GO:0106310; GO:0140469; GO:1900273; GO:1990138; GO:1990253 34638 XM_044327898.1 886 404 432 604 611 Q9QZ05 3.39e-24 eIF-2-alpha kinase GCN2 (Eukaryotic translation initiation factor 2-alpha kinase 4) (EC 2.7.11.1) (GCN2-like protein) (mGCN2) Mus musculus (Mouse) adaptive immune response [GO:0002250]; cell cycle [GO:0007049]; cellular response to amino acid starvation [GO:0034198]; cellular response to cold [GO:0070417]; cellular response to leucine starvation [GO:1990253]; cellular response to starvation [GO:0009267]; cellular response to UV [GO:0034644]; defense response to virus [GO:0051607]; DNA damage checkpoint signaling [GO:0000077]; eiF2alpha phosphorylation in response to endoplasmic reticulum stress [GO:0036492]; endoplasmic reticulum unfolded protein response [GO:0030968]; GCN2-mediated signaling [GO:0140469]; learning [GO:0007612]; long-term memory [GO:0007616]; negative regulation by host of viral genome replication [GO:0044828]; negative regulation of CREB transcription factor activity [GO:0032792]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of translation [GO:0017148]; negative regulation of translational initiation [GO:0045947]; negative regulation of translational initiation in response to stress [GO:0032057]; neuron projection extension [GO:1990138]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of gene expression [GO:0010628]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of translational initiation in response to starvation [GO:0071264]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of feeding behavior [GO:0060259]; regulation of translational initiation [GO:0006446]; regulation of translational initiation by eIF2 alpha phosphorylation [GO:0010998]; regulation of translational initiation in response to stress [GO:0043558]; response to endoplasmic reticulum stress [GO:0034976]; T cell activation involved in immune response [GO:0002286]; viral translation [GO:0019081] GO:0000049; GO:0000077; GO:0001934; GO:0002230; GO:0002250; GO:0002286; GO:0002821; GO:0004672; GO:0004674; GO:0004694; GO:0005524; GO:0005829; GO:0005844; GO:0006446; GO:0006468; GO:0007049; GO:0007612; GO:0007616; GO:0009267; GO:0010628; GO:0010998; GO:0017148; GO:0019081; GO:0022626; GO:0030968; GO:0032057; GO:0032792; GO:0034198; GO:0034644; GO:0034976; GO:0036492; GO:0043558; GO:0044828; GO:0045665; GO:0045947; GO:0046777; GO:0051607; GO:0060259; GO:0070417; GO:0071074; GO:0071264; GO:0106310; GO:0140469; GO:1900273; GO:1990138; GO:1990253 34639 XR_003826096.2 434 787 371 549 311 NA NA NA NA NA NA 34640 XM_029342165.2 46 185 24 38 0 Q96L93 1.02e-103 Kinesin-like protein KIF16B (Sorting nexin-23) Homo sapiens (Human) early endosome to late endosome transport [GO:0045022]; endoderm development [GO:0007492]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; formation of primary germ layer [GO:0001704]; Golgi to endosome transport [GO:0006895]; microtubule-based movement [GO:0007018]; receptor catabolic process [GO:0032801]; regulation of receptor recycling [GO:0001919] GO:0001704; GO:0001919; GO:0003777; GO:0005524; GO:0005547; GO:0005737; GO:0005768; GO:0005769; GO:0005819; GO:0005829; GO:0005871; GO:0005874; GO:0006895; GO:0007018; GO:0007173; GO:0007492; GO:0008017; GO:0008543; GO:0008574; GO:0016887; GO:0031901; GO:0032266; GO:0032801; GO:0043325; GO:0045022; GO:0080025 34641 XM_029345255.2 15 0 0 14 4 Q94887 1.48e-35 Neurexin-4 (Neurexin IV) Drosophila melanogaster (Fruit fly) axon ensheathment [GO:0008366]; cell adhesion involved in heart morphogenesis [GO:0061343]; cell-cell junction organization [GO:0045216]; dorsal closure [GO:0007391]; establishment of glial blood-brain barrier [GO:0060857]; heart process [GO:0003015]; nerve maturation [GO:0021682]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]; synaptic target recognition [GO:0008039]; terminal button organization [GO:0072553] GO:0003015; GO:0005886; GO:0005919; GO:0007391; GO:0008039; GO:0008104; GO:0008366; GO:0019991; GO:0021682; GO:0035151; GO:0045202; GO:0045216; GO:0048786; GO:0060857; GO:0061343; GO:0072553; GO:0097105 34642 XM_044320064.1 18 0 18 28 10 NA NA NA NA NA NA 34643 XR_003824055.2 550 335 234 399 432 O46043 6.42e-39 Poly(ADP-ribose) glycohydrolase (EC 3.2.1.143) Drosophila melanogaster (Fruit fly) ATP generation from poly-ADP-D-ribose [GO:1990966]; Cajal body organization [GO:0030576]; carbohydrate metabolic process [GO:0005975]; female germ-line stem cell population maintenance [GO:0036099]; heterochromatin formation [GO:0031507]; maintenance of protein location in nucleus [GO:0051457]; nucleotide-sugar metabolic process [GO:0009225]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of RNA splicing [GO:0043484]; response to heat [GO:0009408] GO:0004649; GO:0005634; GO:0005654; GO:0005737; GO:0005975; GO:0006282; GO:0009225; GO:0009408; GO:0030576; GO:0031056; GO:0031507; GO:0036099; GO:0043484; GO:0051457; GO:1990966 34644 XM_029324783.2 23 6 61 7 124 Q9H0Z9 1.64e-31 RNA-binding protein 38 (CLL-associated antigen KW-5) (HSRNASEB) (RNA-binding motif protein 38) (RNA-binding region-containing protein 1) (ssDNA-binding protein SEB4) Homo sapiens (Human) 3'-UTR-mediated mRNA stabilization [GO:0070935]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; mRNA processing [GO:0006397]; mRNA stabilization [GO:0048255]; negative regulation of cell population proliferation [GO:0008285]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of cell cycle [GO:0051726]; regulation of myotube differentiation [GO:0010830]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380] GO:0000381; GO:0003723; GO:0003729; GO:0003730; GO:0005634; GO:0005829; GO:0006397; GO:0006977; GO:0006978; GO:0007049; GO:0008285; GO:0008380; GO:0010830; GO:0030154; GO:0043484; GO:0048255; GO:0051726; GO:0070935 34645 XM_044319662.1 1 0 0 0 43 NA NA NA NA NA NA 34646 XM_029339030.2 32 13 25 30 22 Q9DCL2 2.08e-52 Cytosolic iron-sulfur assembly component 2A (MIP18 family protein FAM96A) Mus musculus (Mouse) chromosome segregation [GO:0007059]; iron-sulfur cluster assembly [GO:0016226]; protein maturation by [4Fe-4S] cluster transfer [GO:0106035]; protein maturation by iron-sulfur cluster transfer [GO:0097428] GO:0005654; GO:0005829; GO:0007059; GO:0016226; GO:0046872; GO:0097361; GO:0097428; GO:0106035 34647 XM_029336058.2 702 390 502 693 938 NA NA NA NA NA NA 34648 XR_006393272.1 14 0 89 0 100 NA NA NA NA NA NA 34649 XM_044321639.1 126 107 138 0 0 P49914 4.79e-54 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) (5,10-methenyl-tetrahydrofolate synthetase) (MTHFS) (Methenyl-THF synthetase) Homo sapiens (Human) folic acid catabolic process [GO:0046657]; folic acid metabolic process [GO:0046655]; folic acid-containing compound biosynthetic process [GO:0009396]; formate metabolic process [GO:0015942]; glutamate metabolic process [GO:0006536]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653] GO:0005524; GO:0005542; GO:0005737; GO:0005739; GO:0005759; GO:0005829; GO:0006536; GO:0009396; GO:0015942; GO:0030272; GO:0035999; GO:0046653; GO:0046655; GO:0046657; GO:0046872 34650 XM_029342469.2 5 8 22 16 16 NA NA NA NA NA NA 34651 XR_006396649.1 107 41 47 80 38 NA NA NA NA NA NA 34652 XM_029350793.2 1300 1097 737 1147 840 Q8NG66 1.11e-114 Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (Never in mitosis A-related kinase 11) (NimA-related protein kinase 11) Homo sapiens (Human) chromosome segregation [GO:0007059]; intracellular signal transduction [GO:0035556]; mitotic intra-S DNA damage checkpoint signaling [GO:0031573]; protein phosphorylation [GO:0006468]; regulation of mitotic cell cycle phase transition [GO:1901990] GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005813; GO:0006468; GO:0007059; GO:0031573; GO:0035556; GO:0046872; GO:0106310; GO:1901990 34653 XM_029333065.2 407 630 587 563 867 NA NA NA NA NA NA 34654 XR_006397675.1 202 108 39 102 321 NA NA NA NA NA NA 34655 XM_044321041.1 0 0 0 68 0 C3ZQF9 5.02e-30 QRFP-like peptide receptor Branchiostoma floridae (Florida lancelet) (Amphioxus) cellular response to peptide [GO:1901653]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:1901653 34656 XM_029341190.2 441 393 314 299 436 NA NA NA NA NA NA 34657 XM_029341616.2 0 90 153 0 23 Q5PRF9 1.65e-73 Protein Smaug homolog 2 (Smaug 2) (hSmaug2) (Sterile alpha motif domain-containing protein 4B) (SAM domain-containing protein 4B) Homo sapiens (Human) nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289] GO:0000289; GO:0000932; GO:0003723; GO:0003729; GO:0005634; GO:0005829; GO:0030371 34658 XM_044326125.1 9 3 2 1 18 D3YXG0 3.29e-36 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 34659 XM_044326125.1 9 3 2 1 18 D3YXG0 2.9e-33 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 34660 XM_044326125.1 9 3 2 1 18 D3YXG0 1.31e-31 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 34661 XM_044326125.1 9 3 2 1 18 D3YXG0 3.44e-31 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 34662 XM_044326125.1 9 3 2 1 18 D3YXG0 9.83e-31 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 34663 XM_044326125.1 9 3 2 1 18 D3YXG0 1e-30 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 34664 XM_044326125.1 9 3 2 1 18 D3YXG0 1.09e-30 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 34665 XM_044326125.1 9 3 2 1 18 D3YXG0 1.67e-30 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 34666 XM_044326125.1 9 3 2 1 18 D3YXG0 2.19e-30 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 34667 XM_044326125.1 9 3 2 1 18 D3YXG0 3.48e-30 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 34668 XM_044326125.1 9 3 2 1 18 D3YXG0 2.72e-29 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 34669 XM_044326125.1 9 3 2 1 18 D3YXG0 1.26e-28 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 34670 XM_044326125.1 9 3 2 1 18 D3YXG0 1.96e-27 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 34671 XM_044326125.1 9 3 2 1 18 D3YXG0 2.86e-27 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 34672 XM_044326125.1 9 3 2 1 18 D3YXG0 4.68e-27 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 34673 XM_044326125.1 9 3 2 1 18 D3YXG0 5.55e-27 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 34674 XM_044326125.1 9 3 2 1 18 D3YXG0 1.58e-25 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 34675 XM_044326125.1 9 3 2 1 18 D3YXG0 6.5e-25 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 34676 XM_044326125.1 9 3 2 1 18 D3YXG0 7.45e-25 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 34677 XM_044326125.1 9 3 2 1 18 D3YXG0 1.29e-24 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 34678 XM_044326125.1 9 3 2 1 18 D3YXG0 1.88e-24 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 34679 XM_044326125.1 9 3 2 1 18 D3YXG0 6.83e-23 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 34680 XM_044326125.1 9 3 2 1 18 D3YXG0 1.31e-22 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 34681 XM_044326125.1 9 3 2 1 18 D3YXG0 1.35e-22 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 34682 XM_044323440.1 56 67 17 0 0 NA NA NA NA NA NA 34683 XM_029353610.2 56 85 77 48 67 Q9NVH0 1.15e-27 Exonuclease 3'-5' domain-containing protein 2 (EC 3.1.11.1) (3'-5' exoribonuclease EXD2) (EC 3.1.13.-) (Exonuclease 3'-5' domain-like-containing protein 2) Homo sapiens (Human) DNA double-strand break processing [GO:0000729]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; replication fork processing [GO:0031297] GO:0000175; GO:0000287; GO:0000724; GO:0000729; GO:0003676; GO:0005634; GO:0005737; GO:0005739; GO:0005741; GO:0005759; GO:0006302; GO:0008296; GO:0008310; GO:0008408; GO:0008852; GO:0030145; GO:0031297; GO:0042803; GO:0045111; GO:0090305; GO:0090734 34684 XM_029332858.2 0 87 0 18 0 NA NA NA NA NA NA 34685 XM_029334447.2 54 0 0 0 0 O13018 6.82e-43 Vertebrate ancient opsin Salmo salar (Atlantic salmon) phototransduction, visible light [GO:0007603] GO:0004930; GO:0007603; GO:0009881; GO:0016020 34686 XM_044312841.1 2017 1285 920 1206 1010 NA NA NA NA NA NA 34687 XM_044309177.1 878 194 121 32 0 NA NA NA NA NA NA 34688 XM_029335362.2 74 112 312 93 331 P30884 7.23e-76 Bone morphogenetic protein 2-B (BMP-2-II) Xenopus laevis (African clawed frog) cartilage development [GO:0051216]; cell differentiation [GO:0030154]; ossification [GO:0001503] GO:0001503; GO:0005125; GO:0005615; GO:0008083; GO:0030154; GO:0051216 34689 XR_003822945.2 15 0 3 0 3 NA NA NA NA NA NA 34690 XM_044328704.1 0 9 0 7 13 NA NA NA NA NA NA 34691 XM_029329887.2 172 52 75 17 239 NA NA NA NA NA NA 34692 XM_029349150.2 918 636 530 895 926 Q5ZLF0 5.22e-67 Hsc70-interacting protein (Hip) (Protein FAM10A1) (Protein ST13 homolog) Gallus gallus (Chicken) chaperone cofactor-dependent protein refolding [GO:0051085] GO:0005737; GO:0030544; GO:0046983; GO:0051085 34693 XR_006395278.1 47 40 20 49 75 NA NA NA NA NA NA 34694 XM_029343054.2 45 47 6 40 34 NA NA NA NA NA NA 34695 XM_029337677.2 29 11 38 17 26 NA NA NA NA NA NA 34696 XM_044313376.1 13 20 27 2 29 Q96AY4 4.51e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34697 XM_044313376.1 13 20 27 2 29 Q96AY4 2.61e-73 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34698 XM_044313376.1 13 20 27 2 29 Q96AY4 8.5e-70 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34699 XM_044313376.1 13 20 27 2 29 Q96AY4 2.16e-68 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34700 XM_044313376.1 13 20 27 2 29 Q96AY4 1.26e-65 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34701 XM_044313376.1 13 20 27 2 29 Q96AY4 1.47e-65 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34702 XM_044313376.1 13 20 27 2 29 Q96AY4 3.04e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34703 XM_044307150.1 71 3427 4436 1383 1927 NA NA NA NA NA NA 34704 XM_044316327.1 1313 229 236 825 643 NA NA NA NA NA NA 34705 XM_044327015.1 364 129 135 396 505 NA NA NA NA NA NA 34706 XM_029324640.2 168 113 70 146 175 Q6GNS1 4.92e-32 Carbohydrate sulfotransferase 10 (EC 2.8.2.-) (HNK-1 sulfotransferase) (HNK-1ST) (HNK1ST) Xenopus laevis (African clawed frog) carbohydrate biosynthetic process [GO:0016051] GO:0000139; GO:0008146; GO:0016051 34707 XM_044310167.1 0 0 1 11 0 NA NA NA NA NA NA 34708 XM_029328283.2 77 115 41 164 139 NA NA NA NA NA NA 34709 XM_044310662.1 1 0 20 2 40 NA NA NA NA NA NA 34710 XM_044312978.1 13 0 0 15 14 NA NA NA NA NA NA 34711 XM_029331835.2 10671 22238 10072 46327 28628 NA NA NA NA NA NA 34712 XM_044326025.1 0 78 0 0 0 Q8CJG0 3.74e-153 Protein argonaute-2 (Argonaute2) (mAgo2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (Piwi/argonaute family protein meIF2C2) (Protein slicer) Mus musculus (Mouse) cell differentiation [GO:0030154]; miRNA metabolic process [GO:0010586]; miRNA processing [GO:0035196]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; miRNA-mediated gene silencing by mRNA destabilization [GO:0035279]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; negative regulation of translational initiation [GO:0045947]; positive regulation of angiogenesis [GO:0045766]; positive regulation of gene expression [GO:0010628]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of trophoblast cell migration [GO:1901165]; post-embryonic development [GO:0009791]; pre-miRNA processing [GO:0031054]; RISC complex assembly [GO:0070922]; RNA secondary structure unwinding [GO:0010501]; RNA-mediated gene silencing [GO:0031047]; siRNA processing [GO:0030422]; siRNA-mediated gene silencing by mRNA destabilization [GO:0090625] GO:0000340; GO:0000932; GO:0000993; GO:0001046; GO:0003723; GO:0003725; GO:0003727; GO:0003729; GO:0004521; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0005844; GO:0005845; GO:0008022; GO:0009791; GO:0010501; GO:0010586; GO:0010628; GO:0016442; GO:0030154; GO:0030422; GO:0030425; GO:0031047; GO:0031054; GO:0035196; GO:0035197; GO:0035198; GO:0035278; GO:0035279; GO:0036464; GO:0042985; GO:0045766; GO:0045944; GO:0045947; GO:0046872; GO:0060213; GO:0070062; GO:0070551; GO:0070578; GO:0070922; GO:0090624; GO:0090625; GO:0098808; GO:1900153; GO:1901165; GO:1990904 34713 XM_029328670.2 0 0 204 252 433 NA NA NA NA NA NA 34714 XM_029335552.2 20 937 625 24 281 NA NA NA NA NA NA 34715 XM_029323995.2 1252 1070 628 765 797 NA NA NA NA NA NA 34716 XM_044323023.1 152 0 0 0 0 P02466 4.38e-46 Collagen alpha-2(I) chain (Alpha-2 type I collagen) Rattus norvegicus (Rat) blood vessel development [GO:0001568]; bone mineralization [GO:0030282]; cellular response to amino acid stimulus [GO:0071230]; cellular response to organic substance [GO:0071310]; cellular response to retinoic acid [GO:0071300]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; extracellular matrix assembly [GO:0085029]; extracellular matrix organization [GO:0030198]; protein heterotrimerization [GO:0070208]; regulation of blood pressure [GO:0008217]; response to norepinephrine [GO:0071873]; Rho protein signal transduction [GO:0007266]; skeletal system development [GO:0001501]; skin morphogenesis [GO:0043589]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001501; GO:0001568; GO:0002020; GO:0005201; GO:0005576; GO:0005581; GO:0005584; GO:0005615; GO:0007179; GO:0007266; GO:0008217; GO:0030198; GO:0030199; GO:0030282; GO:0030674; GO:0031012; GO:0032963; GO:0042802; GO:0043589; GO:0046332; GO:0046872; GO:0048407; GO:0062023; GO:0070208; GO:0071230; GO:0071300; GO:0071310; GO:0071873; GO:0085029; GO:0097067 34717 XR_006394778.1 41 9 12 0 7 NA NA NA NA NA NA 34718 XM_029338638.2 281 231 119 181 199 NA NA NA NA NA NA 34719 XM_029338483.2 672 1 238 158 794 A2AAY5 1.63e-50 SH3 and PX domain-containing protein 2B (Factor for adipocyte differentiation 49) (Tyrosine kinase substrate with four SH3 domains) Mus musculus (Mouse) adipose tissue development [GO:0060612]; bone development [GO:0060348]; cranial skeletal system development [GO:1904888]; extracellular matrix disassembly [GO:0022617]; eye development [GO:0001654]; heart development [GO:0007507]; osteoblast fate commitment [GO:0002051]; podosome assembly [GO:0071800]; positive regulation of adipose tissue development [GO:1904179]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of gene expression [GO:0010628]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of stress fiber assembly [GO:0051496]; protein localization to membrane [GO:0072657]; regulation of brood size [GO:0060378]; skeletal system development [GO:0001501]; skeletal system morphogenesis [GO:0048705]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801] GO:0001501; GO:0001654; GO:0002051; GO:0002102; GO:0005737; GO:0006801; GO:0007507; GO:0010314; GO:0010628; GO:0016176; GO:0022617; GO:0032266; GO:0040018; GO:0042169; GO:0042554; GO:0042995; GO:0045600; GO:0048705; GO:0051496; GO:0060348; GO:0060378; GO:0060612; GO:0070161; GO:0070273; GO:0071800; GO:0072657; GO:0080025; GO:1904179; GO:1904888 34720 XM_029336326.2 61 108 117 532 136 NA NA NA NA NA NA 34721 XM_044326087.1 0 0 0 0 10 NA NA NA NA NA NA 34722 XM_044315708.1 81 0 61 304 369 NA NA NA NA NA NA 34723 XR_006396695.1 370 147 266 244 778 NA NA NA NA NA NA 34724 XM_029327986.2 2449 1577 1471 2116 1640 Q06190 8.58e-165 Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha (PP2A subunit B isoform PR72/PR130) (PP2A subunit B isoform R3 isoform) (PP2A subunit B isoforms B''-PR72/PR130) (PP2A subunit B isoforms B72/B130) (Serine/threonine-protein phosphatase 2A 72/130 kDa regulatory subunit B) Homo sapiens (Human) eye photoreceptor cell differentiation [GO:0001754]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of protein catabolic process [GO:0045732]; protein dephosphorylation [GO:0006470]; regulation of cell migration involved in somitogenic axis elongation [GO:0090249]; somatic muscle development [GO:0007525]; somite development [GO:0061053]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0000159; GO:0001754; GO:0005509; GO:0006470; GO:0007525; GO:0019888; GO:0030674; GO:0045732; GO:0061053; GO:0090090; GO:0090244; GO:0090249; GO:0090263 34725 XR_006391374.1 688 249 21 669 1053 NA NA NA NA NA NA 34726 XM_029339279.2 8 0 0 39 0 NA NA NA NA NA NA 34727 XM_029358248.2 35 0 13 13 25 Q6R5J2 0 Protein dispatched homolog 1 (Protein chameleon) Danio rerio (Zebrafish) (Brachydanio rerio) adenohypophysis development [GO:0021984]; animal organ morphogenesis [GO:0009887]; anterior/posterior pattern specification [GO:0009952]; blood circulation [GO:0008015]; embryonic cranial skeleton morphogenesis [GO:0048701]; inner ear development [GO:0048839]; muscle cell fate specification [GO:0042694]; retinal ganglion cell axon guidance [GO:0031290]; skeletal muscle tissue development [GO:0007519]; smoothened signaling pathway [GO:0007224]; transmembrane transport [GO:0055085] GO:0007224; GO:0007519; GO:0008015; GO:0009887; GO:0009952; GO:0016020; GO:0021984; GO:0022857; GO:0031290; GO:0042694; GO:0048701; GO:0048839; GO:0055085; GO:1904680 34728 XM_029356605.2 0 0 3 0 11 NA NA NA NA NA NA 34729 XM_029338460.2 961 1117 884 1303 1183 NA NA NA NA NA NA 34730 XM_029345076.2 0 7 0 6 2 NA NA NA NA NA NA 34731 XM_044312173.1 0 0 8 0 1 NA NA NA NA NA NA 34732 XM_044323395.1 74 1 57 10 103 Q9VBW3 2.28e-64 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 34733 XM_029350730.2 12 10 5 16 2 NA NA NA NA NA NA 34734 XM_029331449.2 191 201 648 233 171 J7GQ11 2.06e-66 L-tyrosine decarboxylase (TDC) (EC 4.1.1.25) Levilactobacillus brevis (Lactobacillus brevis) carboxylic acid metabolic process [GO:0019752] GO:0004837; GO:0019752; GO:0030170; GO:0036468 34735 XR_006391276.1 35 17 47 21 93 P33206 6.24e-40 Forkhead box protein A4-B (FoxA4-B) (FoxA4b) (Fork head domain-related protein 1') (FKH-1) (Forkhead protein 1) (xFD-1') (xFKH1) Xenopus laevis (African clawed frog) cell differentiation [GO:0030154]; negative regulation of DNA-templated transcription [GO:0045892]; nervous system development [GO:0007399]; regulation of DNA-templated transcription [GO:0006355] GO:0003677; GO:0003700; GO:0005634; GO:0006355; GO:0007399; GO:0019904; GO:0030154; GO:0043565; GO:0045892 34736 XM_029333243.2 485 400 159 566 420 Q8N6G5 3.09e-89 Chondroitin sulfate N-acetylgalactosaminyltransferase 2 (EC 2.4.1.174) (Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 2) (Beta4GalNAcT-2) (GalNAcT-2) Homo sapiens (Human) chondroitin sulfate biosynthetic process [GO:0030206]; chondroitin sulfate proteoglycan biosynthetic process [GO:0050650]; chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0050653]; dermatan sulfate proteoglycan biosynthetic process [GO:0050651]; dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0050652]; proteoglycan biosynthetic process [GO:0030166] GO:0000139; GO:0008376; GO:0016020; GO:0030166; GO:0030206; GO:0032580; GO:0046872; GO:0047237; GO:0047238; GO:0050650; GO:0050651; GO:0050652; GO:0050653 34737 XR_006392370.1 20 0 2 0 108 NA NA NA NA NA NA 34738 XM_044309954.1 8 4 0 1 5 Q96AY4 1.22e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34739 XM_044327562.1 2021 1644 1202 1257 1641 Q8WXE9 4.3e-67 Stonin-2 (Stoned B) Homo sapiens (Human) regulation of endocytosis [GO:0030100]; synaptic vesicle endocytosis [GO:0048488]; vesicle-mediated transport [GO:0016192] GO:0005730; GO:0005829; GO:0008021; GO:0016020; GO:0016192; GO:0030100; GO:0030136; GO:0031410; GO:0035615; GO:0043005; GO:0048488 34740 XM_044315543.1 51 58 23 75 0 NA NA NA NA NA NA 34741 XM_044315240.1 97 60 0 39 146 NA NA NA NA NA NA 34742 XM_029339870.2 180 157 153 103 238 NA NA NA NA NA NA 34743 XM_029349478.2 829 790 467 1096 812 Q99PW8 0 Kinesin-like protein KIF17 (MmKIF17) Mus musculus (Mouse) anterograde dendritic transport of neurotransmitter receptor complex [GO:0098971]; cell projection organization [GO:0030030]; intraciliary transport [GO:0042073]; microtubule-based movement [GO:0007018]; microtubule-based process [GO:0007017]; protein transport [GO:0015031]; protein-containing complex localization [GO:0031503]; vesicle-mediated transport [GO:0016192] GO:0001750; GO:0001917; GO:0003777; GO:0005524; GO:0005815; GO:0005829; GO:0005871; GO:0005874; GO:0005929; GO:0005930; GO:0007017; GO:0007018; GO:0008017; GO:0008574; GO:0015031; GO:0015630; GO:0016192; GO:0016887; GO:0030030; GO:0031503; GO:0032391; GO:0032839; GO:0036064; GO:0042073; GO:0043005; GO:0098971; GO:1990075 34744 XM_029349478.2 829 790 467 1096 812 Q99PW8 7.39e-33 Kinesin-like protein KIF17 (MmKIF17) Mus musculus (Mouse) anterograde dendritic transport of neurotransmitter receptor complex [GO:0098971]; cell projection organization [GO:0030030]; intraciliary transport [GO:0042073]; microtubule-based movement [GO:0007018]; microtubule-based process [GO:0007017]; protein transport [GO:0015031]; protein-containing complex localization [GO:0031503]; vesicle-mediated transport [GO:0016192] GO:0001750; GO:0001917; GO:0003777; GO:0005524; GO:0005815; GO:0005829; GO:0005871; GO:0005874; GO:0005929; GO:0005930; GO:0007017; GO:0007018; GO:0008017; GO:0008574; GO:0015031; GO:0015630; GO:0016192; GO:0016887; GO:0030030; GO:0031503; GO:0032391; GO:0032839; GO:0036064; GO:0042073; GO:0043005; GO:0098971; GO:1990075 34745 XM_044309100.1 489 1587 464 0 555 NA NA NA NA NA NA 34746 XR_006394005.1 35 0 31 11 0 NA NA NA NA NA NA 34747 XR_006396228.1 107 3 62 10 96 NA NA NA NA NA NA 34748 XM_029335873.2 303 314 240 432 399 Q9HA64 3.22e-88 Ketosamine-3-kinase (EC 2.7.1.172) (Fructosamine-3-kinase-related protein) (FN3K-RP) (FN3K-related protein) (Protein-psicosamine 3-kinase FN3KRP) (EC 2.7.1.-) Homo sapiens (Human) phosphorylation [GO:0016310]; post-translational protein modification [GO:0043687] GO:0005524; GO:0005829; GO:0016301; GO:0016310; GO:0043687; GO:0102193 34749 XM_029358629.2 1243 1250 1589 1263 1413 B9FAF3 8.7e-94 Kinesin-like protein KIN-14E Oryza sativa subsp. japonica (Rice) microtubule-based movement [GO:0007018]; microtubule-based process [GO:0007017] GO:0003777; GO:0005524; GO:0005874; GO:0007017; GO:0007018; GO:0008017; GO:0015630 34750 XM_044320686.1 0 0 7 3 0 NA NA NA NA NA NA 34751 XR_006391392.1 15 5 33 8 91 NA NA NA NA NA NA 34752 XM_044317419.1 49 175 164 98 75 O93430 1e-65 Glycine receptor subunit alphaZ1 Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to amino acid stimulus [GO:0071230]; cellular response to ethanol [GO:0071361]; cellular response to zinc ion [GO:0071294]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; nervous system process [GO:0050877]; neuropeptide signaling pathway [GO:0007218]; regulation of membrane potential [GO:0042391]; regulation of neuron differentiation [GO:0045664]; response to amino acid [GO:0043200]; signal transduction [GO:0007165]; synaptic transmission, glycinergic [GO:0060012] GO:0004888; GO:0005231; GO:0005886; GO:0006811; GO:0007165; GO:0007218; GO:0007268; GO:0007417; GO:0008270; GO:0016594; GO:0016933; GO:0016934; GO:0030425; GO:0030594; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0043200; GO:0043204; GO:0045202; GO:0045211; GO:0045664; GO:0050877; GO:0060012; GO:0071230; GO:0071294; GO:0071361; GO:1902476; GO:1904315 34753 XM_029350963.2 209 188 166 17 98 Q4KLE6 8.49e-75 N-terminal Xaa-Pro-Lys N-methyltransferase 1-B (EC 2.1.1.244) (Alpha N-terminal protein methyltransferase 1A-B) (Methyltransferase-like protein 11A-B) (X-Pro-Lys N-terminal protein methyltransferase 1A-B) (NTM1A-B) Xenopus laevis (African clawed frog) chromosome segregation [GO:0007059]; histone methylation [GO:0016571]; N-terminal peptidyl-glycine methylation [GO:0018013]; N-terminal peptidyl-proline dimethylation [GO:0018016]; N-terminal peptidyl-serine dimethylation [GO:0035572]; N-terminal peptidyl-serine trimethylation [GO:0035573]; spindle organization [GO:0007051] GO:0005634; GO:0007051; GO:0007059; GO:0008276; GO:0016571; GO:0018013; GO:0018016; GO:0035572; GO:0035573; GO:0042054; GO:0071885 34754 XR_006392931.1 41 2 25 5 151 NA NA NA NA NA NA 34755 XM_044309067.1 308 605 93 618 559 Q94B65 1.03e-44 UDP-galactose/UDP-glucose transporter 7 (AtUTr7) Arabidopsis thaliana (Mouse-ear cress) carbohydrate transport [GO:0008643]; lateral root development [GO:0048527]; root hair cell development [GO:0080147]; UDP-galactose transmembrane transport [GO:0072334]; UDP-glucose transmembrane transport [GO:0015786] GO:0000139; GO:0005459; GO:0005460; GO:0005794; GO:0008643; GO:0015297; GO:0015786; GO:0048527; GO:0072334; GO:0080147 34756 XM_029326033.2 0 5 0 5 9 NA NA NA NA NA NA 34757 XM_044312624.1 125 89 103 65 168 NA NA NA NA NA NA 34758 XM_029336608.2 114 113 41 96 88 NA NA NA NA NA NA 34759 XM_044306775.1 299 0 91 0 208 NA NA NA NA NA NA 34760 XM_044313889.1 1 0 42 10 26 NA NA NA NA NA NA 34761 XM_029347156.2 382 0 287 0 307 O88427 0 Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage-gated calcium channel subunit alpha Cav3.2) Mus musculus (Mouse) aldosterone biosynthetic process [GO:0032342]; calcium ion import [GO:0070509]; calcium ion transport [GO:0006816]; cortisol biosynthetic process [GO:0034651]; inorganic cation transmembrane transport [GO:0098662]; membrane depolarization during action potential [GO:0086010]; neuronal action potential [GO:0019228]; positive regulation of acrosome reaction [GO:2000344]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of cardiac muscle cell contraction [GO:0106134]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; sensory perception of pain [GO:0019233] GO:0001518; GO:0005244; GO:0005248; GO:0005634; GO:0005737; GO:0005886; GO:0005891; GO:0005901; GO:0006816; GO:0008332; GO:0016020; GO:0019228; GO:0019233; GO:0030425; GO:0032342; GO:0034651; GO:0034765; GO:0042383; GO:0042391; GO:0043005; GO:0043204; GO:0045211; GO:0045956; GO:0046872; GO:0048787; GO:0070509; GO:0086010; GO:0097110; GO:0098662; GO:0098978; GO:0106134; GO:2000344 34762 XM_029347156.2 382 0 287 0 307 O88427 2.35e-88 Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage-gated calcium channel subunit alpha Cav3.2) Mus musculus (Mouse) aldosterone biosynthetic process [GO:0032342]; calcium ion import [GO:0070509]; calcium ion transport [GO:0006816]; cortisol biosynthetic process [GO:0034651]; inorganic cation transmembrane transport [GO:0098662]; membrane depolarization during action potential [GO:0086010]; neuronal action potential [GO:0019228]; positive regulation of acrosome reaction [GO:2000344]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of cardiac muscle cell contraction [GO:0106134]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; sensory perception of pain [GO:0019233] GO:0001518; GO:0005244; GO:0005248; GO:0005634; GO:0005737; GO:0005886; GO:0005891; GO:0005901; GO:0006816; GO:0008332; GO:0016020; GO:0019228; GO:0019233; GO:0030425; GO:0032342; GO:0034651; GO:0034765; GO:0042383; GO:0042391; GO:0043005; GO:0043204; GO:0045211; GO:0045956; GO:0046872; GO:0048787; GO:0070509; GO:0086010; GO:0097110; GO:0098662; GO:0098978; GO:0106134; GO:2000344 34763 XM_044312695.1 6 0 43 16 40 NA NA NA NA NA NA 34764 XR_006392512.1 29 10 8 10 32 NA NA NA NA NA NA 34765 XM_029354964.2 1489 4291 1687 1464 1108 P41825 0 Heat shock protein 70 A1 Anopheles albimanus (New world malaria mosquito) NA GO:0005524; GO:0140662 34766 XM_044316070.1 1 17 6 0 7 P48052 3.01e-39 Carboxypeptidase A2 (EC 3.4.17.15) Homo sapiens (Human) protein catabolic process in the vacuole [GO:0007039]; proteolysis [GO:0006508] GO:0004180; GO:0004181; GO:0005576; GO:0005615; GO:0005773; GO:0006508; GO:0007039; GO:0008270 34767 XM_029351779.2 0 0 0 0 172 Q99LX5 8.87e-33 Multiple myeloma tumor-associated protein 2 homolog Mus musculus (Mouse) NA NA 34768 XM_029331726.2 135 159 166 149 169 NA NA NA NA NA NA 34769 XR_006396893.1 7 0 7 8 209 NA NA NA NA NA NA 34770 XM_044322759.1 0 0 274 0 0 NA NA NA NA NA NA 34771 XM_029338320.2 16 9 8 31 60 P84239 7.15e-89 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 34772 XR_006397959.1 17 0 0 3 27 NA NA NA NA NA NA 34773 XM_029329549.2 766 966 266 711 409 R1CW23 3.47e-114 Dimethylsulfonioproprionate lyase 7 (DMSP lyase 7) (EC 4.4.1.3) (Dimethylpropiothetin dethiomethylase 7) Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi) NA GO:0047869 34774 XM_029350798.2 465 301 187 335 409 A7SGU3 1.26e-100 Dynactin subunit 6 Nematostella vectensis (Starlet sea anemone) mitotic spindle organization [GO:0007052] GO:0005737; GO:0005869; GO:0007052; GO:0070840 34775 XM_044322447.1 0 0 23 0 0 NA NA NA NA NA NA 34776 XM_029342764.2 0 67 0 49 33 P48547 2.58e-89 Potassium voltage-gated channel subfamily C member 1 (NGK2) (Voltage-gated potassium channel subunit Kv3.1) (Voltage-gated potassium channel subunit Kv4) Homo sapiens (Human) cellular response to xenobiotic stimulus [GO:0071466]; cerebellum development [GO:0021549]; corpus callosum development [GO:0022038]; globus pallidus development [GO:0021759]; optic nerve development [GO:0021554]; positive regulation of voltage-gated potassium channel activity [GO:1903818]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; protein tetramerization [GO:0051262]; response to amine [GO:0014075]; response to auditory stimulus [GO:0010996]; response to fibroblast growth factor [GO:0071774]; response to light intensity [GO:0009642]; response to nerve growth factor [GO:1990089]; response to potassium ion [GO:0035864]; response to toxic substance [GO:0009636] GO:0005249; GO:0005251; GO:0005886; GO:0006813; GO:0008076; GO:0009636; GO:0009642; GO:0009986; GO:0010996; GO:0014075; GO:0016020; GO:0019894; GO:0021549; GO:0021554; GO:0021759; GO:0022038; GO:0030424; GO:0030673; GO:0032590; GO:0032809; GO:0035864; GO:0042734; GO:0044305; GO:0044325; GO:0045211; GO:0051260; GO:0051262; GO:0071466; GO:0071774; GO:0071805; GO:0099508; GO:1903818; GO:1990089 34777 XR_006392477.1 14 0 0 0 0 NA NA NA NA NA NA 34778 XM_044322997.1 65 33 7 99 43 NA NA NA NA NA NA 34779 XM_029329576.2 2747 1975 1560 2377 2689 NA NA NA NA NA NA 34780 XM_044316725.1 143 31 83 75 141 NA NA NA NA NA NA 34781 XM_044317814.1 192 110 72 110 31 O96017 9.64e-159 Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2) Homo sapiens (Human) cell division [GO:0051301]; cellular response to bisphenol A [GO:1903926]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage checkpoint signaling [GO:0000077]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; double-strand break repair [GO:0006302]; G2/M transition of mitotic cell cycle [GO:0000086]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; mitotic DNA damage checkpoint signaling [GO:0044773]; mitotic intra-S DNA damage checkpoint signaling [GO:0031573]; mitotic spindle assembly [GO:0090307]; negative regulation of DNA damage checkpoint [GO:2000002]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of anoikis [GO:2000210]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of protein phosphorylation [GO:0001934]; protein autophosphorylation [GO:0046777]; protein catabolic process [GO:0030163]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of DNA-templated transcription [GO:0006355]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction by p53 class mediator [GO:1901796]; replicative senescence [GO:0090399]; response to glycoside [GO:1903416]; signal transduction in response to DNA damage [GO:0042770]; thymocyte apoptotic process [GO:0070242] GO:0000077; GO:0000086; GO:0001934; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005794; GO:0006302; GO:0006355; GO:0006468; GO:0006974; GO:0006977; GO:0006978; GO:0008630; GO:0016605; GO:0018105; GO:0019901; GO:0030163; GO:0031573; GO:0031625; GO:0042176; GO:0042770; GO:0042771; GO:0042802; GO:0042803; GO:0044773; GO:0045893; GO:0046777; GO:0046872; GO:0050821; GO:0051301; GO:0070242; GO:0071466; GO:0071480; GO:0090307; GO:0090399; GO:0106310; GO:1901796; GO:1903416; GO:1903926; GO:2000002; GO:2000210 34782 XM_029348441.2 235 50 99 131 270 Q2PZL6 3.6e-105 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 34783 XM_029348441.2 235 50 99 131 270 Q2PZL6 1.02e-95 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 34784 XM_029348441.2 235 50 99 131 270 Q2PZL6 1e-94 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 34785 XM_029348441.2 235 50 99 131 270 Q2PZL6 3.05e-88 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 34786 XM_029348441.2 235 50 99 131 270 Q2PZL6 7.66e-81 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 34787 XM_029348441.2 235 50 99 131 270 Q2PZL6 4.43e-79 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 34788 XM_029348441.2 235 50 99 131 270 Q2PZL6 2.54e-72 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 34789 XM_029348441.2 235 50 99 131 270 Q2PZL6 9.19e-71 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 34790 XM_029348441.2 235 50 99 131 270 Q2PZL6 1.96e-57 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 34791 XR_006397481.1 0 0 0 51 0 NA NA NA NA NA NA 34792 XM_029332864.2 1049 1053 951 1507 948 NA NA NA NA NA NA 34793 XM_044308043.1 183 70 140 99 77 P24155 0 Thimet oligopeptidase (EC 3.4.24.15) (Endo-oligopeptidase A) (Endopeptidase 24.15) (PZ-peptidase) (Soluble metallo-endopeptidase) Rattus norvegicus (Rat) intracellular signal transduction [GO:0035556]; peptide catabolic process [GO:0043171]; peptide metabolic process [GO:0006518]; proteolysis [GO:0006508] GO:0004222; GO:0005758; GO:0006508; GO:0006518; GO:0008233; GO:0035556; GO:0042277; GO:0043171; GO:0046872 34794 XM_044329337.1 206 359 0 0 0 P58027 1.52e-130 Amine oxidase [flavin-containing] A (EC 1.4.3.21) (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A) Canis lupus familiaris (Dog) (Canis familiaris) catecholamine metabolic process [GO:0006584]; neurotransmitter catabolic process [GO:0042135] GO:0005739; GO:0005741; GO:0006584; GO:0008131; GO:0042135; GO:0050660; GO:0052595; GO:0052596; GO:0097621 34795 XM_044307491.1 48 22 11 23 23 Q0V8S9 1.59e-24 Contactin-associated protein-like 5 (Cell recognition molecule Caspr5) Gallus gallus (Chicken) cell adhesion [GO:0007155] GO:0007155; GO:0016020 34796 XM_044307491.1 48 22 11 23 23 Q0V8S9 3.84e-24 Contactin-associated protein-like 5 (Cell recognition molecule Caspr5) Gallus gallus (Chicken) cell adhesion [GO:0007155] GO:0007155; GO:0016020 34797 XM_029338647.2 6 2 399 4 48 NA NA NA NA NA NA 34798 XM_044324518.1 142 188 66 144 135 NA NA NA NA NA NA 34799 XM_044321616.1 36 55 70 4 36 Q8BHB0 3.58e-30 Nucleotide-binding oligomerization domain-containing protein 1 (Caspase recruitment domain-containing protein 4) Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cellular response to muramyl dipeptide [GO:0071225]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; ERK1 and ERK2 cascade [GO:0070371]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of cell death [GO:0010942]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of xenophagy [GO:1904417]; regulation of apoptotic process [GO:0042981]; stress-activated MAPK cascade [GO:0051403]; xenophagy [GO:0098792] GO:0002221; GO:0002606; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006915; GO:0006919; GO:0007249; GO:0007254; GO:0010942; GO:0016045; GO:0016323; GO:0016324; GO:0032731; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0035556; GO:0038187; GO:0042742; GO:0042802; GO:0042803; GO:0042981; GO:0043123; GO:0043280; GO:0044877; GO:0045087; GO:0045335; GO:0046330; GO:0050700; GO:0050830; GO:0051000; GO:0051092; GO:0051403; GO:0060907; GO:0070371; GO:0070374; GO:0071225; GO:0098792; GO:1901224; GO:1904417 34800 XM_029347183.2 109 73 22 125 70 Q08DM7 1.41e-128 Neuronal-specific septin-3 Bos taurus (Bovine) cytoskeleton-dependent cytokinesis [GO:0061640] GO:0003924; GO:0005525; GO:0005940; GO:0015630; GO:0031105; GO:0032153; GO:0043005; GO:0060090; GO:0061640; GO:0098793; GO:0099569 34801 XM_029323426.2 316 76 234 141 595 NA NA NA NA NA NA 34802 XM_044328752.1 26 50 57 23 100 NA NA NA NA NA NA 34803 XM_044314116.1 0 0 26 30 121 NA NA NA NA NA NA 34804 XM_044317355.1 1204 926 598 982 1329 Q8CDN6 1.52e-104 Thioredoxin-like protein 1 (32 kDa thioredoxin-related protein) Mus musculus (Mouse) NA GO:0000502; GO:0005634; GO:0005737; GO:0005829; GO:0015035; GO:0015036 34805 XM_029333049.2 91 285 551 84 558 B0CQN7 2.59e-31 NADH-cytochrome b5 reductase 1 (EC 1.6.2.2) (Microsomal cytochrome b reductase) Laccaria bicolor (strain S238N-H82 / ATCC MYA-4686) (Bicoloured deceiver) (Laccaria laccata var. bicolor) peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]; tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation [GO:0002926] GO:0002926; GO:0003954; GO:0004128; GO:0005741; GO:0016740; GO:0017183 34806 XM_029340770.2 290 224 180 126 231 A1L0Y2 0 Neuralized-like protein 4 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737; GO:0005814 34807 XM_029340770.2 290 224 180 126 231 A1L0Y2 2.71e-172 Neuralized-like protein 4 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737; GO:0005814 34808 XM_029340770.2 290 224 180 126 231 A1L0Y2 2.94e-144 Neuralized-like protein 4 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737; GO:0005814 34809 XM_029340770.2 290 224 180 126 231 A1L0Y2 2.05e-142 Neuralized-like protein 4 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737; GO:0005814 34810 XM_029340770.2 290 224 180 126 231 A1L0Y2 8.42e-50 Neuralized-like protein 4 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737; GO:0005814 34811 XM_029340770.2 290 224 180 126 231 A1L0Y2 3.33e-30 Neuralized-like protein 4 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737; GO:0005814 34812 XM_029340770.2 290 224 180 126 231 A1L0Y2 1.04e-23 Neuralized-like protein 4 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737; GO:0005814 34813 XM_029333810.2 966 682 561 979 907 A7SMW7 0 L-2-hydroxyglutarate dehydrogenase, mitochondrial (EC 1.1.99.2) Nematostella vectensis (Starlet sea anemone) NA GO:0005739; GO:0047545 34814 XM_029357080.2 271 312 380 452 322 NA NA NA NA NA NA 34815 XM_044328716.1 12 29 82 62 122 NA NA NA NA NA NA 34816 XM_029346440.2 644 485 513 340 317 Q62077 0 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-1) (Phospholipase C-gamma-1) (PLC-gamma-1) Mus musculus (Mouse) calcium ion transport [GO:0006816]; calcium-mediated signaling [GO:0019722]; cell migration [GO:0016477]; cellular response to epidermal growth factor stimulus [GO:0071364]; epidermal growth factor receptor signaling pathway [GO:0007173]; in utero embryonic development [GO:0001701]; inositol trisphosphate biosynthetic process [GO:0032959]; inositol trisphosphate metabolic process [GO:0032957]; modulation of chemical synaptic transmission [GO:0050804]; phosphatidylinositol catabolic process [GO:0031161]; phosphatidylinositol metabolic process [GO:0046488]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; protein secretion [GO:0009306]; regulation of store-operated calcium channel activity [GO:1901339]; response to curcumin [GO:1904643]; response to organonitrogen compound [GO:0010243]; T cell receptor signaling pathway [GO:0050852] GO:0001701; GO:0001726; GO:0004435; GO:0004629; GO:0005158; GO:0005168; GO:0005509; GO:0005737; GO:0005829; GO:0005886; GO:0005911; GO:0006816; GO:0007173; GO:0008180; GO:0009306; GO:0010243; GO:0010634; GO:0016020; GO:0016477; GO:0019722; GO:0019901; GO:0030027; GO:0030136; GO:0030971; GO:0031161; GO:0032587; GO:0032957; GO:0032959; GO:0035254; GO:0042995; GO:0043005; GO:0043536; GO:0045766; GO:0046488; GO:0050429; GO:0050804; GO:0050852; GO:0051219; GO:0051281; GO:0071364; GO:0098685; GO:0098978; GO:1901339; GO:1904643; GO:1905564; GO:2000353 34817 XM_029356812.2 4534 2431 2475 3921 5516 NA NA NA NA NA NA 34818 XM_044307852.1 0 28 0 24 171 NA NA NA NA NA NA 34819 XM_044324625.1 10 4 2 5 46 NA NA NA NA NA NA 34820 XM_044324026.1 1736 647 570 1889 1378 Q6DE75 1.2e-93 Mitochondrial glycine transporter (Solute carrier family 25 member 38) Xenopus laevis (African clawed frog) erythrocyte differentiation [GO:0030218]; glycine import into mitochondrion [GO:1904983] GO:0005743; GO:0015187; GO:0030218; GO:1904983 34821 XM_029340727.2 617 743 155 484 811 Q98TA5 2.53e-37 Chromatin assembly factor 1 subunit A-A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit A) (CAF-I 150 kDa subunit A) (CAF-I p150-A) (xp150) Xenopus laevis (African clawed frog) cell cycle [GO:0007049]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication-dependent chromatin assembly [GO:0006335]; nucleosome assembly [GO:0006334] GO:0005634; GO:0006260; GO:0006281; GO:0006334; GO:0006335; GO:0007049; GO:0033186 34822 XM_029338533.2 95 66 86 183 194 NA NA NA NA NA NA 34823 XR_006391733.1 19 71 29 122 122 NA NA NA NA NA NA 34824 XM_044314744.1 147 0 0 56 306 NA NA NA NA NA NA 34825 XM_044325372.1 399 157 237 392 421 Q3BSE3 1.38e-130 Protein adenylyltransferase SelO (EC 2.7.7.108) Xanthomonas campestris pv. vesicatoria (strain 85-10) NA GO:0000287; GO:0005524; GO:0016779 34826 XM_029358382.2 838 692 310 1163 588 B3EWZ2 6.02e-129 Uncharacterized skeletal organic matrix protein 8 (Uncharacterized SOMP-8) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 34827 XM_029343043.2 0 0 1 2 13 NA NA NA NA NA NA 34828 XM_029324024.2 2173 1084 805 1720 1566 Q9W3F7 2.64e-58 Mitoguardin Drosophila melanogaster (Fruit fly) mitochondrial fusion [GO:0008053]; mitochondrion morphogenesis [GO:0070584]; photoreceptor cell maintenance [GO:0045494]; regulation of mitochondrial fusion [GO:0010635] GO:0005739; GO:0005741; GO:0008053; GO:0010635; GO:0045494; GO:0070584 34829 XM_029338073.2 144 90 55 89 130 NA NA NA NA NA NA 34830 XM_044310770.1 21 8 13 28 16 NA NA NA NA NA NA 34831 XM_044310091.1 29 6 36 88 115 NA NA NA NA NA NA 34832 XM_044325931.1 3 0 0 0 94 NA NA NA NA NA NA 34833 XM_029327030.2 25 51 13 91 28 P81139 1.46e-68 Pancreatic lipase-related protein 2 (PL-RP2) (Cytotoxic T lymphocyte lipase) (GPL) (Galactolipase) (EC 3.1.1.26) (Triacylglycerol lipase) (EC 3.1.1.3) Cavia porcellus (Guinea pig) galactolipid catabolic process [GO:0019376]; lipid metabolic process [GO:0006629]; phospholipid catabolic process [GO:0009395]; phospholipid metabolic process [GO:0006644]; triglyceride catabolic process [GO:0019433] GO:0004620; GO:0004806; GO:0005509; GO:0005615; GO:0006629; GO:0006644; GO:0009395; GO:0016020; GO:0019376; GO:0019433; GO:0031410; GO:0043005; GO:0047372; GO:0047714; GO:0102549 34834 XM_044325716.1 100 143 75 124 196 NA NA NA NA NA NA 34835 XM_029334380.2 1600 729 741 607 404 B3EWY9 3.51e-41 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 34836 XM_029334380.2 1600 729 741 607 404 B3EWY9 1.09e-33 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 34837 XM_029337895.2 933 678 416 678 526 Q3KQ77 2.6e-56 Calaxin (EF-hand calcium-binding domain-containing protein 1) Xenopus laevis (African clawed frog) cilium movement [GO:0003341]; outer dynein arm assembly [GO:0036158]; regulation of cilium movement [GO:0003352]; regulation of flagellated sperm motility [GO:1901317] GO:0003341; GO:0003352; GO:0005509; GO:0005737; GO:0005856; GO:0005929; GO:0036158; GO:1901317 34838 XM_029330668.2 589 805 385 510 316 Q8VYX1 2.99e-171 NA NA NA NA 34839 XR_006394614.1 16 223 7 179 194 NA NA NA NA NA NA 34840 XM_029329315.2 0 123 0 186 102 NA NA NA NA NA NA 34841 XM_029342511.2 3 0 0 6 17 NA NA NA NA NA NA 34842 XM_029340820.2 86 48 39 87 9 P25102 9.06e-34 Histamine H2 receptor (H2R) (HH2R) (Gastric receptor I) Rattus norvegicus (Rat) cellular response to histamine [GO:0071420]; chemical synaptic transmission [GO:0007268]; digestive tract development [GO:0048565]; epithelial cell morphogenesis [GO:0003382]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; gastric acid secretion [GO:0001696]; gastrin-induced gastric acid secretion [GO:0001698]; gland development [GO:0048732]; histamine-induced gastric acid secretion [GO:0001697]; memory [GO:0007613]; negative regulation of arachidonic acid secretion [GO:1900139]; positive regulation of vasoconstriction [GO:0045907]; regulation of synaptic plasticity [GO:0048167]; toxin transport [GO:1901998]; visual learning [GO:0008542] GO:0001696; GO:0001697; GO:0001698; GO:0003382; GO:0004969; GO:0004993; GO:0005886; GO:0007187; GO:0007268; GO:0007613; GO:0008542; GO:0016020; GO:0030425; GO:0030594; GO:0045202; GO:0045907; GO:0048167; GO:0048565; GO:0048732; GO:0071420; GO:1900139; GO:1901363; GO:1901998 34843 XM_029340910.2 320 182 85 205 237 B2RPY5 1.59e-21 G-protein coupled receptor 161 Mus musculus (Mouse) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:1901621] GO:0004930; GO:0005929; GO:0007186; GO:0007189; GO:0043005; GO:0055037; GO:0060170; GO:0097386; GO:1901621 34844 XM_029324752.2 2642 1630 629 1019 1166 Q9H0Z9 1.55e-31 RNA-binding protein 38 (CLL-associated antigen KW-5) (HSRNASEB) (RNA-binding motif protein 38) (RNA-binding region-containing protein 1) (ssDNA-binding protein SEB4) Homo sapiens (Human) 3'-UTR-mediated mRNA stabilization [GO:0070935]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; mRNA processing [GO:0006397]; mRNA stabilization [GO:0048255]; negative regulation of cell population proliferation [GO:0008285]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of cell cycle [GO:0051726]; regulation of myotube differentiation [GO:0010830]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380] GO:0000381; GO:0003723; GO:0003729; GO:0003730; GO:0005634; GO:0005829; GO:0006397; GO:0006977; GO:0006978; GO:0007049; GO:0008285; GO:0008380; GO:0010830; GO:0030154; GO:0043484; GO:0048255; GO:0051726; GO:0070935 34845 XM_044311223.1 10 9 18 0 51 B3EWZ5 2.12e-22 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 34846 XM_044311223.1 10 9 18 0 51 B3EWZ5 4.12e-22 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 34847 XM_044311223.1 10 9 18 0 51 B3EWZ5 1.86e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 34848 XM_044311223.1 10 9 18 0 51 B3EWZ5 2.12e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 34849 XM_044313329.1 1807 690 676 2526 1674 Q9GLN7 0 Angiotensin-converting enzyme (ACE) (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (CD antigen CD143) [Cleaved into: Angiotensin-converting enzyme, soluble form] Pan troglodytes (Chimpanzee) angiotensin maturation [GO:0002003]; bradykinin catabolic process [GO:0010815]; hormone catabolic process [GO:0042447]; hormone metabolic process [GO:0042445]; kidney development [GO:0001822]; positive regulation of systemic arterial blood pressure [GO:0003084]; regulation of blood pressure [GO:0008217]; regulation of synaptic plasticity [GO:0048167]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; substance P catabolic process [GO:0010814] GO:0001822; GO:0002003; GO:0003081; GO:0003084; GO:0004180; GO:0004222; GO:0005516; GO:0005576; GO:0005615; GO:0005737; GO:0005886; GO:0008217; GO:0008233; GO:0008237; GO:0008241; GO:0010814; GO:0010815; GO:0031404; GO:0042445; GO:0042447; GO:0046872; GO:0048167; GO:0070573 34850 XM_029341324.2 2 5 0 1 16 NA NA NA NA NA NA 34851 XM_029345101.2 230 195 67 226 197 Q9DBW0 2.46e-159 Cytochrome P450 4V2 (Docosahexaenoic acid omega-hydroxylase CYP4V2) (EC 1.14.14.79) (Long-chain fatty acid omega-monooxygenase) (EC 1.14.14.80) Mus musculus (Mouse) fatty acid omega-oxidation [GO:0010430] GO:0005506; GO:0005789; GO:0010430; GO:0020037; GO:0102033 34852 XM_029351739.2 14 4276 14 5141 4019 P17244 0 Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (EC 1.2.1.12) (Peptidyl-cysteine S-nitrosylase GAPDH) (EC 2.6.99.-) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]; innate immune response [GO:0045087]; microtubule cytoskeleton organization [GO:0000226]; neuron apoptotic process [GO:0051402]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of type I interferon production [GO:0032481]; protein stabilization [GO:0050821]; regulation of translation [GO:0006417] GO:0000226; GO:0004365; GO:0005634; GO:0005737; GO:0005829; GO:0006006; GO:0006096; GO:0006417; GO:0008017; GO:0015630; GO:0032481; GO:0035605; GO:0035606; GO:0043123; GO:0045087; GO:0050661; GO:0050821; GO:0051287; GO:0051402; GO:0097452 34853 XM_029344857.2 183 146 54 129 169 NA NA NA NA NA NA 34854 XR_006393405.1 0 0 0 0 13 NA NA NA NA NA NA 34855 XM_044324681.1 680 395 182 304 211 Q8C0W1 1.97e-61 Ankyrin repeat and MYND domain-containing protein 1 Mus musculus (Mouse) NA GO:0046872 34856 XM_044324681.1 680 395 182 304 211 Q8C0W1 1.74e-22 Ankyrin repeat and MYND domain-containing protein 1 Mus musculus (Mouse) NA GO:0046872 34857 XM_044311953.1 1 0 24 1 29 NA NA NA NA NA NA 34858 XM_044315880.1 0 0 23 0 14 NA NA NA NA NA NA 34859 XM_029357450.2 0 0 0 202 152 Q80TC6 0 Zinc finger SWIM domain-containing protein 5 Mus musculus (Mouse) NA GO:0008270; GO:0031462 34860 XM_029324196.2 7 0 4 5 15 NA NA NA NA NA NA 34861 XR_006391537.1 0 73 81 56 78 NA NA NA NA NA NA 34862 XM_029343612.2 0 0 0 6 3 NA NA NA NA NA NA 34863 XM_029324925.1 7347 5285 4010 6120 5118 Q2HJ23 1e-45 Microtubule-associated proteins 1A/1B light chain 3A (Autophagy-related protein LC3 A) (Autophagy-related ubiquitin-like modifier LC3 A) (MAP1 light chain 3-like protein 1) (MAP1A/MAP1B light chain 3 A) (MAP1A/MAP1B LC3 A) (Microtubule-associated protein 1 light chain 3 alpha) Bos taurus (Bovine) autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; macroautophagy [GO:0016236] GO:0000045; GO:0000421; GO:0000422; GO:0005543; GO:0005776; GO:0005829; GO:0005874; GO:0006995; GO:0008017; GO:0012505; GO:0016236; GO:0031090; GO:0031410; GO:0031625; GO:0097352 34864 XR_006395764.1 42 12 13 38 22 NA NA NA NA NA NA 34865 XM_044307360.1 10 55 34 6 4 NA NA NA NA NA NA 34866 XR_003826337.2 2659 2944 641 3149 3315 NA NA NA NA NA NA 34867 XM_029337170.2 363 303 262 255 531 NA NA NA NA NA NA 34868 XM_029335145.2 2 7 0 0 2 A7SLC8 1.53e-57 N-acetyltransferase 9-like protein (EC 2.3.1.-) Nematostella vectensis (Starlet sea anemone) protein acetylation [GO:0006473] GO:0006473; GO:0008080 34869 XM_029334936.2 0 5 0 0 90 NA NA NA NA NA NA 34870 XM_044328532.1 524 254 352 532 980 Q8BYA0 0 Tubulin-specific chaperone D (Beta-tubulin cofactor D) (Tubulin-folding cofactor D) Mus musculus (Mouse) adherens junction assembly [GO:0034333]; bicellular tight junction assembly [GO:0070830]; cell morphogenesis involved in neuron differentiation [GO:0048667]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of microtubule polymerization [GO:0031115]; post-chaperonin tubulin folding pathway [GO:0007023]; protein folding [GO:0006457]; tubulin complex assembly [GO:0007021] GO:0000226; GO:0000278; GO:0005096; GO:0005737; GO:0005813; GO:0005912; GO:0005923; GO:0006457; GO:0007021; GO:0007023; GO:0010812; GO:0016328; GO:0031115; GO:0034333; GO:0048487; GO:0048667; GO:0070830 34871 XM_044323510.1 0 0 1 23 5 NA NA NA NA NA NA 34872 XM_029334728.2 9 16 54 0 88 Q9C0E8 2.15e-56 Endoplasmic reticulum junction formation protein lunapark (ER junction formation factor lunapark) Homo sapiens (Human) blood coagulation [GO:0007596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum tubular network maintenance [GO:0071788]; endoplasmic reticulum tubular network organization [GO:0071786]; limb development [GO:0060173]; positive regulation of endoplasmic reticulum tubular network organization [GO:1903373]; regulation of chondrocyte differentiation [GO:0032330] GO:0005654; GO:0005783; GO:0005789; GO:0007029; GO:0007596; GO:0016020; GO:0032330; GO:0035115; GO:0042733; GO:0042802; GO:0046872; GO:0060173; GO:0071782; GO:0071786; GO:0071788; GO:0098826; GO:1903373 34873 XR_006396986.1 20 17 140 28 265 NA NA NA NA NA NA 34874 XM_044313507.1 7 8 0 2 6 NA NA NA NA NA NA 34875 XM_029346316.2 1589 1501 857 2431 2500 NA NA NA NA NA NA 34876 XM_044308453.1 23675 8363 8373 17574 3361 NA NA NA NA NA NA 34877 XM_029338496.2 3348 2443 1066 2261 2406 Q16932 3.66e-93 Syntaxin Aplysia californica (California sea hare) intracellular protein transport [GO:0006886]; neurotransmitter transport [GO:0006836]; vesicle-mediated transport [GO:0016192] GO:0005484; GO:0006836; GO:0006886; GO:0016020; GO:0016192 34878 XM_029335138.2 221 174 213 289 227 Q5RCV1 4.78e-174 Transmembrane protein 104 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0016020 34879 XM_044308230.1 462 1842 399 173 196 Q9BU40 1.89e-26 Chordin-like protein 1 (Neuralin-1) (Neurogenesin-1) (Ventroptin) Homo sapiens (Human) AMPA glutamate receptor clustering [GO:0097113]; BMP signaling pathway [GO:0030509]; cell differentiation [GO:0030154]; embryonic axis specification [GO:0000578]; excitatory chemical synaptic transmission [GO:0098976]; eye development [GO:0001654]; negative regulation of BMP signaling pathway [GO:0030514]; ossification [GO:0001503]; regulation of synaptic plasticity [GO:0048167]; synapse maturation [GO:0060074] GO:0000578; GO:0001503; GO:0001654; GO:0005576; GO:0005788; GO:0005886; GO:0030154; GO:0030509; GO:0030514; GO:0036122; GO:0045202; GO:0048167; GO:0050431; GO:0060074; GO:0097113; GO:0098976 34880 XM_029337509.2 65 28 25 19 26 Q569C3 6.45e-46 Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.4.19.12) (Deubiquitinating enzyme 1) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) [Cleaved into: Ubiquitin carboxyl-terminal hydrolase 1, N-terminal fragment] Rattus norvegicus (Rat) DNA repair [GO:0006281]; monoubiquitinated protein deubiquitination [GO:0035520]; protein deubiquitination [GO:0016579]; regulation of DNA repair [GO:0006282]; response to UV [GO:0009411]; skeletal system development [GO:0001501]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0001501; GO:0004197; GO:0004843; GO:0005634; GO:0005654; GO:0005829; GO:0006281; GO:0006282; GO:0006511; GO:0008233; GO:0009411; GO:0016579; GO:0035520 34881 XM_029337720.2 13 33 6 91 92 Q9D4G9 2.66e-28 RecQ-mediated genome instability protein 1 Mus musculus (Mouse) DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; glucose homeostasis [GO:0042593]; multicellular organism growth [GO:0035264]; reduction of food intake in response to dietary excess [GO:0002023]; resolution of meiotic recombination intermediates [GO:0000712]; resolution of recombination intermediates [GO:0071139]; response to dietary excess [GO:0002021]; response to glucose [GO:0009749] GO:0000166; GO:0000712; GO:0000724; GO:0002021; GO:0002023; GO:0005634; GO:0005654; GO:0006260; GO:0009749; GO:0016604; GO:0031422; GO:0035264; GO:0042593; GO:0071139 34882 XM_044322769.1 3440 3433 2913 3769 8929 Q3TZZ7 3.84e-113 Extended synaptotagmin-2 (E-Syt2) Mus musculus (Mouse) endocytosis [GO:0006897]; endoplasmic reticulum-plasma membrane tethering [GO:0061817]; lipid transport [GO:0006869] GO:0005509; GO:0005544; GO:0005789; GO:0005829; GO:0005886; GO:0006869; GO:0006897; GO:0008429; GO:0031210; GO:0031234; GO:0035091; GO:0042802; GO:0044232; GO:0061817; GO:0140268 34883 XM_044322769.1 3440 3433 2913 3769 8929 Q3TZZ7 3.83e-30 Extended synaptotagmin-2 (E-Syt2) Mus musculus (Mouse) endocytosis [GO:0006897]; endoplasmic reticulum-plasma membrane tethering [GO:0061817]; lipid transport [GO:0006869] GO:0005509; GO:0005544; GO:0005789; GO:0005829; GO:0005886; GO:0006869; GO:0006897; GO:0008429; GO:0031210; GO:0031234; GO:0035091; GO:0042802; GO:0044232; GO:0061817; GO:0140268 34884 XM_044307758.1 8 0 13 4 21 NA NA NA NA NA NA 34885 XM_044307571.1 83 67 31 132 90 P13608 1.65e-25 Aggrecan core protein (Cartilage-specific proteoglycan core protein) (CSPCP) Bos taurus (Bovine) cell adhesion [GO:0007155]; central nervous system development [GO:0007417]; skeletal system development [GO:0001501] GO:0001501; GO:0005509; GO:0005540; GO:0005576; GO:0007155; GO:0007417; GO:0030246; GO:0031012 34886 XM_044309004.1 0 0 24 0 0 NA NA NA NA NA NA 34887 XM_029346287.2 200 91 142 221 280 P08953 1.07e-60 Protein toll Drosophila melanogaster (Fruit fly) antifungal innate immune response [GO:0061760]; cell adhesion [GO:0007155]; cell competition in a multicellular organism [GO:0035212]; defense response to Gram-positive bacterium [GO:0050830]; defense response to oomycetes [GO:0002229]; detection of virus [GO:0009597]; dorsal/ventral axis specification [GO:0009950]; heart development [GO:0007507]; innate immune response [GO:0045087]; larval somatic muscle development [GO:0007526]; negative regulation of cell growth [GO:0030308]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of multicellular organism growth [GO:0040015]; positive regulation of antifungal peptide production [GO:0002804]; positive regulation of antimicrobial peptide production [GO:0002225]; positive regulation of hemocyte proliferation [GO:0035208]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of embryonic pattern specification [GO:1902875]; response to tumor cell [GO:0002347]; response to wounding [GO:0009611]; synapse assembly [GO:0007416]; synaptic target inhibition [GO:0016201]; Toll signaling pathway [GO:0008063]; toll-like receptor signaling pathway [GO:0002224] GO:0002224; GO:0002225; GO:0002229; GO:0002347; GO:0002804; GO:0004888; GO:0004896; GO:0005769; GO:0005886; GO:0007155; GO:0007416; GO:0007507; GO:0007526; GO:0008063; GO:0009597; GO:0009611; GO:0009897; GO:0009950; GO:0009986; GO:0016201; GO:0019955; GO:0030308; GO:0032154; GO:0035208; GO:0035212; GO:0038023; GO:0040015; GO:0042802; GO:0045087; GO:0045944; GO:0046627; GO:0046790; GO:0050135; GO:0050830; GO:0061760; GO:0061809; GO:0070976; GO:1902875 34888 XM_029330205.2 216 0 193 68 423 NA NA NA NA NA NA 34889 XM_044318235.1 2 10 11 14 9 E7FAM5 2.35e-62 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 34890 XM_044317086.1 0 0 3 10 53 P36544 3.85e-85 Neuronal acetylcholine receptor subunit alpha-7 Homo sapiens (Human) acetylcholine receptor signaling pathway [GO:0095500]; calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; cognition [GO:0050890]; dendrite arborization [GO:0140059]; dendritic spine organization [GO:0097061]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; learning or memory [GO:0007611]; membrane depolarization [GO:0051899]; memory [GO:0007613]; modulation of excitatory postsynaptic potential [GO:0098815]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of tumor necrosis factor production [GO:0032720]; nervous system process [GO:0050877]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of CoA-transferase activity [GO:1905920]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; regulation of amyloid fibril formation [GO:1905906]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of membrane potential [GO:0042391]; regulation of neuron death [GO:1901214]; regulation of nitric oxide metabolic process [GO:0080164]; response to acetylcholine [GO:1905144]; response to amyloid-beta [GO:1904645]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; sensory processing [GO:0050893]; short-term memory [GO:0007614]; signal transduction [GO:0007165]; synapse organization [GO:0050808]; synaptic transmission, cholinergic [GO:0007271] GO:0001540; GO:0001666; GO:0001934; GO:0005216; GO:0005231; GO:0005262; GO:0005886; GO:0005892; GO:0006811; GO:0006816; GO:0006874; GO:0007165; GO:0007268; GO:0007271; GO:0007611; GO:0007613; GO:0007614; GO:0008284; GO:0015464; GO:0015643; GO:0016020; GO:0017081; GO:0022848; GO:0030594; GO:0032720; GO:0034220; GO:0035094; GO:0042166; GO:0042391; GO:0042803; GO:0043005; GO:0043410; GO:0044853; GO:0045202; GO:0045211; GO:0045766; GO:0050808; GO:0050877; GO:0050890; GO:0050893; GO:0051247; GO:0051899; GO:0070374; GO:0080164; GO:0095500; GO:0097061; GO:0098794; GO:0098815; GO:0140059; GO:1900273; GO:1901214; GO:1902004; GO:1902430; GO:1902991; GO:1904315; GO:1904645; GO:1905144; GO:1905906; GO:1905920; GO:2000463 34891 XM_029332420.2 341 181 160 245 320 Q922B6 1.99e-98 E3 ubiquitin-protein ligase TRAF7 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TRAF7) (TNF receptor-associated factor 7) Mus musculus (Mouse) apoptotic process [GO:0006915]; cellular response to interleukin-6 [GO:0071354]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein sumoylation [GO:0033235]; protein ubiquitination [GO:0016567]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of protein localization [GO:0032880]; ribosomal large subunit assembly [GO:0000027] GO:0000027; GO:0000122; GO:0000151; GO:0004842; GO:0005634; GO:0005730; GO:0005829; GO:0005886; GO:0006915; GO:0007219; GO:0008270; GO:0016567; GO:0031410; GO:0032880; GO:0033235; GO:0043231; GO:0043410; GO:0043525; GO:0048471; GO:0070372; GO:0071354; GO:2001235 34892 XM_044308832.1 83 45 98 19 153 NA NA NA NA NA NA 34893 XM_044323276.1 168 132 187 232 197 NA NA NA NA NA NA 34894 XM_029332300.2 398 126 25 895 523 Q0P8I7 3.44e-78 GDP-D-glycero-alpha-D-manno-heptose dehydrogenase (EC 1.1.98.-) Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) capsule polysaccharide biosynthetic process [GO:0045227]; protein homotetramerization [GO:0051289] GO:0003978; GO:0016491; GO:0019003; GO:0042802; GO:0045227; GO:0051289; GO:0070404 34895 XM_029340710.2 198 1 0 1 28 Q9NQX0 9.04e-91 Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.361) (PR domain zinc finger protein 6) (PR domain-containing protein 6) Homo sapiens (Human) chromatin organization [GO:0006325]; histone methylation [GO:0016571]; negative regulation of smooth muscle cell differentiation [GO:0051151]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of gene expression [GO:0010468] GO:0000122; GO:0005634; GO:0006325; GO:0010468; GO:0016571; GO:0022008; GO:0042802; GO:0046872; GO:0051151; GO:0140944 34896 XM_029331539.2 1277 1299 1123 1081 1570 Q9WVK8 1.82e-105 Cholesterol 24-hydroxylase (CH24H) (EC 1.14.14.25) (Cholesterol 24-monooxygenase) (Cholesterol 24S-hydroxylase) (Cytochrome P450 46A1) Mus musculus (Mouse) cholesterol catabolic process [GO:0006707]; progesterone metabolic process [GO:0042448]; protein localization to membrane raft [GO:1903044]; regulation of long-term synaptic potentiation [GO:1900271]; xenobiotic metabolic process [GO:0006805] GO:0005506; GO:0005789; GO:0006707; GO:0006805; GO:0008395; GO:0020037; GO:0030425; GO:0033781; GO:0042448; GO:0062184; GO:0098793; GO:0098794; GO:1900271; GO:1903044 34897 XM_029338409.2 1286 644 559 1311 784 Q96S52 8.51e-90 GPI transamidase component PIG-S (Phosphatidylinositol-glycan biosynthesis class S protein) Homo sapiens (Human) attachment of GPI anchor to protein [GO:0016255] GO:0005789; GO:0016020; GO:0016255; GO:0042765 34898 XM_044328524.1 0 45 9 6 7 Q8K2J9 7.44e-83 BTB/POZ domain-containing protein 6 Mus musculus (Mouse) neurogenesis [GO:0022008] GO:0005829; GO:0022008 34899 XM_044325827.1 3103 1263 396 3327 901 NA NA NA NA NA NA 34900 XM_029338652.2 0 0 0 0 62 P47937 3.25e-29 Neuromedin-K receptor (NKR) (NK-3 receptor) (NK-3R) (Neurokinin B receptor) (Tachykinin receptor 3) Mus musculus (Mouse) aging [GO:0007568]; hyperosmotic salinity response [GO:0042538]; positive regulation of blood pressure [GO:0045777]; positive regulation of flagellated sperm motility [GO:1902093]; positive regulation of heart rate [GO:0010460]; positive regulation of uterine smooth muscle contraction [GO:0070474]; regulation of dopamine metabolic process [GO:0042053]; regulation of feeding behavior [GO:0060259]; response to cocaine [GO:0042220]; response to estradiol [GO:0032355]; response to morphine [GO:0043278] GO:0004995; GO:0005634; GO:0005737; GO:0005886; GO:0007568; GO:0010460; GO:0016020; GO:0032355; GO:0032590; GO:0032809; GO:0042053; GO:0042220; GO:0042538; GO:0043278; GO:0045777; GO:0060259; GO:0070474; GO:0097225; GO:1902093 34901 XM_044314675.1 0 6 0 0 10 NA NA NA NA NA NA 34902 XM_029333295.2 17442 18649 9226 16621 12264 P49165 2.47e-142 60S ribosomal protein L4 (L1) Urechis caupo (Innkeeper worm) (Spoonworm) translation [GO:0006412] GO:0003735; GO:0005840; GO:0006412; GO:1990904 34903 XM_029336709.2 6 40 3 87 100 NA NA NA NA NA NA 34904 XM_029338036.2 926 829 549 864 1094 Q92621 0 Nuclear pore complex protein Nup205 (205 kDa nucleoporin) (Nucleoporin Nup205) Homo sapiens (Human) mRNA transport [GO:0051028]; nuclear pore complex assembly [GO:0051292]; nuclear pore organization [GO:0006999]; nucleocytoplasmic transport [GO:0006913]; protein transport [GO:0015031] GO:0005635; GO:0005643; GO:0005829; GO:0006913; GO:0006999; GO:0015031; GO:0016020; GO:0017056; GO:0031965; GO:0034399; GO:0044611; GO:0051028; GO:0051292 34905 XM_029352788.2 364 188 176 208 280 Q6EJB6 7.65e-43 U3 small nucleolar RNA-associated protein 14 homolog B (Juvenile spermatogonial depletion protein) Mus musculus (Mouse) cell differentiation [GO:0030154]; meiotic cell cycle [GO:0051321]; rRNA processing [GO:0006364]; spermatogenesis [GO:0007283] GO:0005730; GO:0005829; GO:0006364; GO:0007283; GO:0030154; GO:0032040; GO:0051321 34906 XM_029352788.2 364 188 176 208 280 Q6EJB6 5.63e-37 U3 small nucleolar RNA-associated protein 14 homolog B (Juvenile spermatogonial depletion protein) Mus musculus (Mouse) cell differentiation [GO:0030154]; meiotic cell cycle [GO:0051321]; rRNA processing [GO:0006364]; spermatogenesis [GO:0007283] GO:0005730; GO:0005829; GO:0006364; GO:0007283; GO:0030154; GO:0032040; GO:0051321 34907 XM_029336963.2 526 137 138 393 502 O95685 6.28e-23 Protein phosphatase 1 regulatory subunit 3D (Protein phosphatase 1 regulatory subunit 6) (PP1 subunit R6) (Protein phosphatase 1-binding subunit R6) Homo sapiens (Human) glycogen metabolic process [GO:0005977]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of glycogen catabolic process [GO:0005981] GO:0000164; GO:0004722; GO:0005977; GO:0005979; GO:0005981; GO:0008157; GO:0042587; GO:0043231; GO:2001069 34908 XR_006396840.1 0 0 0 6 0 NA NA NA NA NA NA 34909 XR_006391790.1 13 0 4 11 0 NA NA NA NA NA NA 34910 XM_029358656.2 109 47 46 185 203 Q71B07 1.72e-168 Probable C-mannosyltransferase DPY19L3 (EC 2.4.1.-) (Dpy-19-like protein 3) (Protein dpy-19 homolog 3) Mus musculus (Mouse) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan [GO:0018406] GO:0000030; GO:0005637; GO:0018406 34911 XM_029342215.2 1621 1580 984 1374 1798 Q96NB2 5.26e-120 Sideroflexin-2 Homo sapiens (Human) mitochondrial transmembrane transport [GO:1990542]; serine import into mitochondrion [GO:0140300] GO:0005739; GO:0005741; GO:0005743; GO:0022857; GO:0022889; GO:0140300; GO:1990542 34912 XM_044320971.1 10 24 11 29 45 NA NA NA NA NA NA 34913 XM_044325375.1 591 808 115 54 609 Q9C0D7 1.16e-85 Probable ribonuclease ZC3H12C (EC 3.1.-.-) (MCP-induced protein 3) (Zinc finger CCCH domain-containing protein 12C) Homo sapiens (Human) RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502] GO:0003729; GO:0004521; GO:0005634; GO:0036464; GO:0046872; GO:0090502 34914 XR_003822748.2 130 118 339 86 52 NA NA NA NA NA NA 34915 XM_044324017.1 1 6 3 9 0 NA NA NA NA NA NA 34916 XR_006391506.1 486 239 104 297 258 NA NA NA NA NA NA 34917 XM_044325400.1 810 755 510 1382 776 Q5RAG8 2.54e-136 Prolyl 4-hydroxylase subunit alpha-1 (4-PH alpha-1) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0004656; GO:0005506; GO:0005739; GO:0005788; GO:0031418; GO:0042802 34918 XM_029356905.2 355 423 186 270 207 Q1JQ66 2.36e-118 Solute carrier family 35 member E3 Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005338; GO:0005794; GO:0015297; GO:0016020 34919 XM_029349625.2 21 0 18 1 41 NA NA NA NA NA NA 34920 XM_044310488.1 23 0 0 34 24 NA NA NA NA NA NA 34921 XM_044324246.1 736 379 274 774 992 Q864S8 3.05e-148 Breast cancer type 2 susceptibility protein homolog (Fanconi anemia group D1 protein homolog) Felis catus (Cat) (Felis silvestris catus) centrosome duplication [GO:0051298]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; nucleotide-excision repair [GO:0006289]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA-templated transcription [GO:0006355] GO:0000724; GO:0003677; GO:0005634; GO:0005813; GO:0006289; GO:0006302; GO:0006355; GO:0030141; GO:0032991; GO:0033593; GO:0033600; GO:0043015; GO:0045893; GO:0051298 34922 XM_029335190.2 197 300 212 281 154 P49842 3.43e-58 Serine/threonine-protein kinase 19 (EC 2.7.11.1) (Protein G11) (Protein RP1) Homo sapiens (Human) positive regulation of Ras protein signal transduction [GO:0046579]; protein phosphorylation [GO:0006468] GO:0004674; GO:0005524; GO:0005634; GO:0006468; GO:0016607; GO:0031267; GO:0046579; GO:0106310 34923 XM_044326772.1 39 0 0 0 26 P00774 1.08e-46 Chymotrypsin-like elastase family member 2A (EC 3.4.21.71) (Elastase-2) (Elastase-2A) Rattus norvegicus (Rat) insulin catabolic process [GO:1901143]; proteolysis [GO:0006508]; regulation of insulin secretion [GO:0050796]; regulation of platelet aggregation [GO:0090330]; response to insulin [GO:0032868] GO:0004175; GO:0004252; GO:0005576; GO:0005615; GO:0006508; GO:0017171; GO:0032868; GO:0036457; GO:0050796; GO:0090330; GO:1901143 34924 XM_044328068.1 732 325 516 679 693 Q8BGC4 1.07e-131 Prostaglandin reductase-3 (PTGR-3) (EC 1.3.1.48) (15-oxoprostaglandin 13-reductase) (Zinc-binding alcohol dehydrogenase domain-containing protein 2) Mus musculus (Mouse) negative regulation of fat cell differentiation [GO:0045599] GO:0005739; GO:0005777; GO:0008270; GO:0016491; GO:0036132; GO:0045599; GO:0047522 34925 XM_044319845.1 526 264 189 478 436 Q5HZL5 7.32e-31 Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase A (EC 2.4.1.206) (Lactotriaosylceramide synthase A) (Lc(3)Cer synthase A) (Lc3 synthase A) (UDP-GlcNAc:beta-Gal beta-1,3-N-acetylglucosaminyltransferase 5A) (BGnT-5A) (Beta-1,3-Gn-T5A) (Beta-1,3-N-acetylglucosaminyltransferase 5A) (Beta3Gn-T5A) Xenopus laevis (African clawed frog) protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0008457; GO:0047256 34926 XM_044306756.1 21 0 0 0 0 P42696 4.79e-44 RNA-binding protein 34 (RNA-binding motif protein 34) Homo sapiens (Human) NA GO:0003723; GO:0005654; GO:0005694; GO:0005730 34927 XM_044308413.1 32 7 15 13 0 NA NA NA NA NA NA 34928 XM_029336366.2 192 109 69 136 122 NA NA NA NA NA NA 34929 XM_029358486.2 512 441 600 2332 1118 NA NA NA NA NA NA 34930 XM_029333448.2 179 67 123 109 93 NA NA NA NA NA NA 34931 XM_029344579.2 17 0 23 0 0 Q9HAC7 1.11e-164 Succinate--hydroxymethylglutarate CoA-transferase (EC 2.8.3.13) (Dermal papilla-derived protein 13) (SuccinylCoA:glutarate-CoA transferase) Homo sapiens (Human) NA GO:0005739; GO:0047369 34932 XM_029332427.2 0 38 44 34 44 Q6PC60 7.06e-59 Histone H2B 3 Danio rerio (Zebrafish) (Brachydanio rerio) nucleosome assembly [GO:0006334] GO:0000785; GO:0000786; GO:0003677; GO:0005634; GO:0006334; GO:0030527; GO:0046982 34933 XM_029334387.2 319 868 559 795 516 Q04073 1.13e-113 DNA-binding protein P3A2 Strongylocentrotus purpuratus (Purple sea urchin) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357 34934 XM_029357132.2 565 338 282 426 525 Q4QY64 4.03e-28 ATPase family AAA domain-containing protein 5 (Chromosome fragility-associated gene 1 protein) Mus musculus (Mouse) cell population proliferation [GO:0008283]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; isotype switching [GO:0045190]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902230]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; nuclear DNA replication [GO:0033260]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell cycle G2/M phase transition [GO:1902751]; positive regulation of DNA replication [GO:0045740]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; regulation of mitotic cell cycle phase transition [GO:1901990]; signal transduction in response to DNA damage [GO:0042770] GO:0003677; GO:0005524; GO:0005634; GO:0006974; GO:0008283; GO:0008630; GO:0016887; GO:0030890; GO:0031391; GO:0033260; GO:0042770; GO:0042771; GO:0045190; GO:0045740; GO:0048304; GO:0061860; GO:0090305; GO:1901990; GO:1902166; GO:1902230; GO:1902751 34935 XM_029357132.2 565 338 282 426 525 Q4QY64 3.78e-23 ATPase family AAA domain-containing protein 5 (Chromosome fragility-associated gene 1 protein) Mus musculus (Mouse) cell population proliferation [GO:0008283]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; isotype switching [GO:0045190]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902230]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; nuclear DNA replication [GO:0033260]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell cycle G2/M phase transition [GO:1902751]; positive regulation of DNA replication [GO:0045740]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; regulation of mitotic cell cycle phase transition [GO:1901990]; signal transduction in response to DNA damage [GO:0042770] GO:0003677; GO:0005524; GO:0005634; GO:0006974; GO:0008283; GO:0008630; GO:0016887; GO:0030890; GO:0031391; GO:0033260; GO:0042770; GO:0042771; GO:0045190; GO:0045740; GO:0048304; GO:0061860; GO:0090305; GO:1901990; GO:1902166; GO:1902230; GO:1902751 34936 XM_044323805.1 774 252 0 531 476 Q4LDE5 0 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 34937 XM_044323805.1 774 252 0 531 476 Q4LDE5 0 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 34938 XM_044323805.1 774 252 0 531 476 Q4LDE5 9.79e-176 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 34939 XM_044323805.1 774 252 0 531 476 Q4LDE5 2.27e-171 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 34940 XM_044323805.1 774 252 0 531 476 Q4LDE5 5.71e-166 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 34941 XM_044323805.1 774 252 0 531 476 Q4LDE5 5.08e-165 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 34942 XM_044323805.1 774 252 0 531 476 Q4LDE5 6.46e-156 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 34943 XM_029323604.2 4903 6487 3691 5635 2690 NA NA NA NA NA NA 34944 XM_029357421.2 0 0 0 0 109 NA NA NA NA NA NA 34945 XR_003825896.2 269 370 104 345 187 NA NA NA NA NA NA 34946 XM_044306896.1 192 125 45 52 243 Q9TU19 2.7e-120 Nephrocystin-1 Canis lupus familiaris (Dog) (Canis familiaris) cell differentiation [GO:0030154]; cell projection organization [GO:0030030]; protein localization involved in establishment of planar polarity [GO:0090251]; spermatogenesis [GO:0007283] GO:0005737; GO:0005856; GO:0005911; GO:0005912; GO:0005923; GO:0005929; GO:0007283; GO:0030030; GO:0030154; GO:0090251 34947 XM_044326587.1 0 163 0 0 0 Q91285 6.15e-77 Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (PFR1) Pleurodeles waltl (Iberian ribbed newt) positive regulation of cell population proliferation [GO:0008284] GO:0005007; GO:0005524; GO:0005634; GO:0005829; GO:0005886; GO:0008284; GO:0031410 34948 XM_029343262.2 1484 1893 968 1673 2690 Q8RDT4 7.95e-113 L-methionine gamma-lyase (MGL) (EC 4.4.1.11) (Homocysteine desulfhydrase) (EC 4.4.1.2) (L-cysteine desulfidase) (EC 4.4.1.28) Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / DSM 15643 / BCRC 10681 / CIP 101130 / JCM 8532 / KCTC 2640 / LMG 13131 / VPI 4355) transsulfuration [GO:0019346] GO:0005737; GO:0016846; GO:0018826; GO:0019346; GO:0030170; GO:0047982; GO:0080146 34949 XM_044317701.1 0 33 0 0 0 Q9HC77 1.01e-87 Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1) Homo sapiens (Human) astral microtubule nucleation [GO:0030954]; cell division [GO:0051301]; centriole elongation [GO:0061511]; centriole replication [GO:0007099]; cilium assembly [GO:0060271]; microtubule nucleation [GO:0007020]; microtubule polymerization [GO:0046785]; motile cilium assembly [GO:0044458]; non-motile cilium assembly [GO:1905515]; positive regulation of centriole elongation [GO:1903724]; positive regulation of centriole replication [GO:0046601]; positive regulation of establishment of protein localization [GO:1904951]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of non-motile cilium assembly [GO:1902857]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of spindle assembly [GO:1905832]; regulation of centriole replication [GO:0046599]; regulation of mitotic spindle organization [GO:0060236]; smoothened signaling pathway [GO:0007224] GO:0003713; GO:0005634; GO:0005737; GO:0005813; GO:0005814; GO:0005829; GO:0005874; GO:0007020; GO:0007099; GO:0007224; GO:0008275; GO:0015631; GO:0019901; GO:0019904; GO:0030954; GO:0036064; GO:0042802; GO:0043015; GO:0044458; GO:0046427; GO:0046599; GO:0046601; GO:0046785; GO:0051301; GO:0060236; GO:0060271; GO:0061511; GO:0120099; GO:1900087; GO:1902857; GO:1903724; GO:1904951; GO:1905515; GO:1905832 34950 XM_044317701.1 0 33 0 0 0 Q9HC77 7.26e-34 Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1) Homo sapiens (Human) astral microtubule nucleation [GO:0030954]; cell division [GO:0051301]; centriole elongation [GO:0061511]; centriole replication [GO:0007099]; cilium assembly [GO:0060271]; microtubule nucleation [GO:0007020]; microtubule polymerization [GO:0046785]; motile cilium assembly [GO:0044458]; non-motile cilium assembly [GO:1905515]; positive regulation of centriole elongation [GO:1903724]; positive regulation of centriole replication [GO:0046601]; positive regulation of establishment of protein localization [GO:1904951]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of non-motile cilium assembly [GO:1902857]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of spindle assembly [GO:1905832]; regulation of centriole replication [GO:0046599]; regulation of mitotic spindle organization [GO:0060236]; smoothened signaling pathway [GO:0007224] GO:0003713; GO:0005634; GO:0005737; GO:0005813; GO:0005814; GO:0005829; GO:0005874; GO:0007020; GO:0007099; GO:0007224; GO:0008275; GO:0015631; GO:0019901; GO:0019904; GO:0030954; GO:0036064; GO:0042802; GO:0043015; GO:0044458; GO:0046427; GO:0046599; GO:0046601; GO:0046785; GO:0051301; GO:0060236; GO:0060271; GO:0061511; GO:0120099; GO:1900087; GO:1902857; GO:1903724; GO:1904951; GO:1905515; GO:1905832 34951 XM_029342986.2 0 0 55 58 242 Q9JID6 0 Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3) (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain acyl-CoA synthetase 1) (LACS 1) (Palmitoyl-CoA ligase) (Phytanate--CoA ligase) (EC 6.2.1.24) Cavia porcellus (Guinea pig) long-chain fatty acid metabolic process [GO:0001676]; very long-chain fatty acid metabolic process [GO:0000038] GO:0000038; GO:0001676; GO:0004467; GO:0005524; GO:0005741; GO:0005778; GO:0005783; GO:0005789; GO:0047676; GO:0050197; GO:0070251 34952 XM_044316350.1 1 0 0 0 12 NA NA NA NA NA NA 34953 XM_029328913.2 220 206 84 326 190 Q641A1 2e-54 Poly(A) RNA polymerase GLD2-A (EC 2.7.7.19) (PAP-associated domain-containing protein 4-A) Xenopus laevis (African clawed frog) mRNA processing [GO:0006397]; negative regulation of miRNA catabolic process [GO:2000626]; oogenesis [GO:0048477]; RNA polyadenylation [GO:0043631]; RNA stabilization [GO:0043489] GO:0004652; GO:0005524; GO:0005737; GO:0006397; GO:0034062; GO:0043489; GO:0043631; GO:0046872; GO:0048477; GO:0070566; GO:2000626 34954 XM_044311064.1 160 124 56 37 64 P16157 1.17e-77 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 34955 XM_044311064.1 160 124 56 37 64 P16157 4.82e-60 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 34956 XM_044311064.1 160 124 56 37 64 P16157 1.08e-55 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 34957 XM_044311064.1 160 124 56 37 64 P16157 5.4e-52 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 34958 XM_044311064.1 160 124 56 37 64 P16157 7.34e-44 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 34959 XM_044311064.1 160 124 56 37 64 P16157 2.26e-23 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 34960 XM_044324029.1 1 2 338 23 279 Q2LE78 2.28e-80 BTB/POZ domain-containing protein 6 Xenopus laevis (African clawed frog) NA GO:0005737 34961 XM_044328794.1 0 12 5 3 29 E9Q236 1.33e-153 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 34962 XM_029341882.2 434 1509 388 543 617 A0A0G2K1Q8 0 Phospholipid-transporting ATPase ABCA3 (EC 7.6.2.1) (ATP-binding cassette sub-family A member 3) (Xenobiotic-transporting ATPase ABCA3) (EC 7.6.2.2) [Cleaved into: 150 Kda mature form] Rattus norvegicus (Rat) lipid transport [GO:0006869]; lung development [GO:0030324]; organelle assembly [GO:0070925]; phosphatidylcholine metabolic process [GO:0046470]; phosphatidylglycerol metabolic process [GO:0046471]; phospholipid homeostasis [GO:0055091]; phospholipid transport [GO:0015914]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of phospholipid efflux [GO:1902995]; positive regulation of phospholipid transport [GO:2001140]; positive regulation of protein homooligomerization [GO:0032464]; regulation of lipid biosynthetic process [GO:0046890]; regulation of lipid transport [GO:0032368]; regulation of phosphatidylcholine metabolic process [GO:0150172]; response to glucocorticoid [GO:0051384]; surfactant homeostasis [GO:0043129]; xenobiotic export from cell [GO:0046618]; xenobiotic transmembrane transport [GO:0006855]; xenobiotic transport [GO:0042908] GO:0005319; GO:0005524; GO:0005765; GO:0005770; GO:0005886; GO:0006855; GO:0006869; GO:0008559; GO:0010875; GO:0015914; GO:0016887; GO:0030324; GO:0030659; GO:0032368; GO:0032464; GO:0032585; GO:0042599; GO:0042626; GO:0042908; GO:0043129; GO:0043231; GO:0046470; GO:0046471; GO:0046618; GO:0046890; GO:0051384; GO:0055091; GO:0070925; GO:0097208; GO:0097232; GO:0097233; GO:0120019; GO:0140345; GO:0150172; GO:1902995; GO:2001140 34963 XM_029341882.2 434 1509 388 543 617 A0A0G2K1Q8 3.92e-120 Phospholipid-transporting ATPase ABCA3 (EC 7.6.2.1) (ATP-binding cassette sub-family A member 3) (Xenobiotic-transporting ATPase ABCA3) (EC 7.6.2.2) [Cleaved into: 150 Kda mature form] Rattus norvegicus (Rat) lipid transport [GO:0006869]; lung development [GO:0030324]; organelle assembly [GO:0070925]; phosphatidylcholine metabolic process [GO:0046470]; phosphatidylglycerol metabolic process [GO:0046471]; phospholipid homeostasis [GO:0055091]; phospholipid transport [GO:0015914]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of phospholipid efflux [GO:1902995]; positive regulation of phospholipid transport [GO:2001140]; positive regulation of protein homooligomerization [GO:0032464]; regulation of lipid biosynthetic process [GO:0046890]; regulation of lipid transport [GO:0032368]; regulation of phosphatidylcholine metabolic process [GO:0150172]; response to glucocorticoid [GO:0051384]; surfactant homeostasis [GO:0043129]; xenobiotic export from cell [GO:0046618]; xenobiotic transmembrane transport [GO:0006855]; xenobiotic transport [GO:0042908] GO:0005319; GO:0005524; GO:0005765; GO:0005770; GO:0005886; GO:0006855; GO:0006869; GO:0008559; GO:0010875; GO:0015914; GO:0016887; GO:0030324; GO:0030659; GO:0032368; GO:0032464; GO:0032585; GO:0042599; GO:0042626; GO:0042908; GO:0043129; GO:0043231; GO:0046470; GO:0046471; GO:0046618; GO:0046890; GO:0051384; GO:0055091; GO:0070925; GO:0097208; GO:0097232; GO:0097233; GO:0120019; GO:0140345; GO:0150172; GO:1902995; GO:2001140 34964 XM_029341882.2 434 1509 388 543 617 A0A0G2K1Q8 2.31e-48 Phospholipid-transporting ATPase ABCA3 (EC 7.6.2.1) (ATP-binding cassette sub-family A member 3) (Xenobiotic-transporting ATPase ABCA3) (EC 7.6.2.2) [Cleaved into: 150 Kda mature form] Rattus norvegicus (Rat) lipid transport [GO:0006869]; lung development [GO:0030324]; organelle assembly [GO:0070925]; phosphatidylcholine metabolic process [GO:0046470]; phosphatidylglycerol metabolic process [GO:0046471]; phospholipid homeostasis [GO:0055091]; phospholipid transport [GO:0015914]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of phospholipid efflux [GO:1902995]; positive regulation of phospholipid transport [GO:2001140]; positive regulation of protein homooligomerization [GO:0032464]; regulation of lipid biosynthetic process [GO:0046890]; regulation of lipid transport [GO:0032368]; regulation of phosphatidylcholine metabolic process [GO:0150172]; response to glucocorticoid [GO:0051384]; surfactant homeostasis [GO:0043129]; xenobiotic export from cell [GO:0046618]; xenobiotic transmembrane transport [GO:0006855]; xenobiotic transport [GO:0042908] GO:0005319; GO:0005524; GO:0005765; GO:0005770; GO:0005886; GO:0006855; GO:0006869; GO:0008559; GO:0010875; GO:0015914; GO:0016887; GO:0030324; GO:0030659; GO:0032368; GO:0032464; GO:0032585; GO:0042599; GO:0042626; GO:0042908; GO:0043129; GO:0043231; GO:0046470; GO:0046471; GO:0046618; GO:0046890; GO:0051384; GO:0055091; GO:0070925; GO:0097208; GO:0097232; GO:0097233; GO:0120019; GO:0140345; GO:0150172; GO:1902995; GO:2001140 34965 XM_029341882.2 434 1509 388 543 617 A0A0G2K1Q8 2.94e-43 Phospholipid-transporting ATPase ABCA3 (EC 7.6.2.1) (ATP-binding cassette sub-family A member 3) (Xenobiotic-transporting ATPase ABCA3) (EC 7.6.2.2) [Cleaved into: 150 Kda mature form] Rattus norvegicus (Rat) lipid transport [GO:0006869]; lung development [GO:0030324]; organelle assembly [GO:0070925]; phosphatidylcholine metabolic process [GO:0046470]; phosphatidylglycerol metabolic process [GO:0046471]; phospholipid homeostasis [GO:0055091]; phospholipid transport [GO:0015914]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of phospholipid efflux [GO:1902995]; positive regulation of phospholipid transport [GO:2001140]; positive regulation of protein homooligomerization [GO:0032464]; regulation of lipid biosynthetic process [GO:0046890]; regulation of lipid transport [GO:0032368]; regulation of phosphatidylcholine metabolic process [GO:0150172]; response to glucocorticoid [GO:0051384]; surfactant homeostasis [GO:0043129]; xenobiotic export from cell [GO:0046618]; xenobiotic transmembrane transport [GO:0006855]; xenobiotic transport [GO:0042908] GO:0005319; GO:0005524; GO:0005765; GO:0005770; GO:0005886; GO:0006855; GO:0006869; GO:0008559; GO:0010875; GO:0015914; GO:0016887; GO:0030324; GO:0030659; GO:0032368; GO:0032464; GO:0032585; GO:0042599; GO:0042626; GO:0042908; GO:0043129; GO:0043231; GO:0046470; GO:0046471; GO:0046618; GO:0046890; GO:0051384; GO:0055091; GO:0070925; GO:0097208; GO:0097232; GO:0097233; GO:0120019; GO:0140345; GO:0150172; GO:1902995; GO:2001140 34966 XM_029340761.2 252 14 40 589 384 P21674 8.32e-38 Follistatin (FS) (Activin-binding protein) Rattus norvegicus (Rat) ameloblast differentiation [GO:0036305]; BMP signaling pathway [GO:0030509]; cell differentiation [GO:0030154]; cellular response to growth factor stimulus [GO:0071363]; female gonad development [GO:0008585]; gamete generation [GO:0007276]; hair follicle morphogenesis [GO:0031069]; hematopoietic progenitor cell differentiation [GO:0002244]; keratinocyte proliferation [GO:0043616]; negative regulation of activin receptor signaling pathway [GO:0032926]; negative regulation of cell differentiation [GO:0045596]; negative regulation of epithelial cell differentiation [GO:0030857]; negative regulation of follicle-stimulating hormone secretion [GO:0046882]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis of dentin-containing tooth [GO:0042475]; pattern specification process [GO:0007389]; positive regulation of hair follicle development [GO:0051798]; regulation of BMP signaling pathway [GO:0030510]; response to organic cyclic compound [GO:0014070]; skeletal system development [GO:0001501] GO:0000122; GO:0001501; GO:0002244; GO:0005615; GO:0005634; GO:0005737; GO:0007276; GO:0007389; GO:0008585; GO:0014070; GO:0030154; GO:0030509; GO:0030510; GO:0030857; GO:0031069; GO:0032926; GO:0036305; GO:0038102; GO:0042475; GO:0043395; GO:0043616; GO:0045596; GO:0046882; GO:0048185; GO:0051798; GO:0071363 34967 XM_044324424.1 22 22 29 72 45 NA NA NA NA NA NA 34968 XR_006392631.1 3 4 31 25 0 NA NA NA NA NA NA 34969 XM_029347185.2 290 164 125 230 175 Q5M7F8 2.58e-25 Protein FAM166C A Xenopus laevis (African clawed frog) NA NA 34970 XM_029354818.2 470 364 286 575 750 A7RLE5 2.28e-61 Putative 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 (EC 3.2.2.-) Nematostella vectensis (Starlet sea anemone) deoxyribonucleoside monophosphate catabolic process [GO:0009159]; nucleoside metabolic process [GO:0009116]; nucleotide metabolic process [GO:0009117]; positive regulation of cell growth [GO:0030307] GO:0005634; GO:0005737; GO:0009116; GO:0009117; GO:0009159; GO:0030307; GO:0070694 34971 XR_006391544.1 13 7 15 11 24 NA NA NA NA NA NA 34972 XM_029328188.2 434 367 301 362 338 A5A6I3 2.84e-103 Eukaryotic translation initiation factor 3 subunit F (eIF3f) (Deubiquitinating enzyme eIF3f) (EC 3.4.19.12) (Eukaryotic translation initiation factor 3 subunit 5) (eIF-3-epsilon) (eIF3 p47) Pan troglodytes (Chimpanzee) formation of cytoplasmic translation initiation complex [GO:0001732]; proteolysis [GO:0006508]; translational initiation [GO:0006413] GO:0001732; GO:0003743; GO:0004843; GO:0005852; GO:0006413; GO:0006508; GO:0008237; GO:0016282; GO:0031369; GO:0033290 34973 XM_029338513.2 1072 1000 825 1540 1018 NA NA NA NA NA NA 34974 XR_006392519.1 0 0 10 20 25 NA NA NA NA NA NA 34975 XM_044317018.1 202 106 57 125 121 NA NA NA NA NA NA 34976 XM_044322731.1 180 134 50 56 266 Q8N653 6.33e-25 Leucine-zipper-like transcriptional regulator 1 (LZTR-1) Homo sapiens (Human) negative regulation of Ras protein signal transduction [GO:0046580]; protein ubiquitination [GO:0016567] GO:0005794; GO:0012505; GO:0016567; GO:0031267; GO:0031463; GO:0046580; GO:0055038 34977 XM_044316232.1 49 4 4 4 19 Q17RP2 1.49e-66 Tigger transposable element-derived protein 6 Homo sapiens (Human) NA GO:0003677; GO:0005634 34978 XM_044320451.1 79 103 105 113 172 NA NA NA NA NA NA 34979 XM_029329719.2 99 336 192 350 108 NA NA NA NA NA NA 34980 XR_003825331.1 65 72 58 93 51 NA NA NA NA NA NA 34981 XM_029355667.2 177 111 82 126 142 Q9DBN9 0 Probable ATP-dependent RNA helicase DDX59 (EC 3.6.4.13) (DEAD box protein 59) (Zinc finger HIT domain-containing protein 5) Mus musculus (Mouse) NA GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005737; GO:0016887; GO:0046872 34982 XM_029330570.2 0 21 0 0 0 A0A3Q2HW92 5.51e-119 Major facilitator superfamily domain-containing protein 12 Equus caballus (Horse) carbohydrate transport [GO:0008643]; cysteine transmembrane transport [GO:1903712]; melanin biosynthetic process [GO:0042438]; negative regulation of melanin biosynthetic process [GO:0048022]; pigment metabolic process involved in pigmentation [GO:0043474] GO:0005764; GO:0005765; GO:0005770; GO:0008643; GO:0015293; GO:0033162; GO:0033229; GO:0042438; GO:0043474; GO:0048022; GO:1903712 34983 XM_029340211.2 204 70 168 106 209 NA NA NA NA NA NA 34984 XM_044315912.1 5 29 15 7 21 NA NA NA NA NA NA 34985 XM_044309901.1 97 98 44 168 274 Q80XJ3 1.09e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 34986 XM_044309901.1 97 98 44 168 274 Q80XJ3 5.84e-65 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 34987 XM_044309901.1 97 98 44 168 274 Q80XJ3 4.02e-61 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 34988 XM_044309901.1 97 98 44 168 274 Q80XJ3 4.54e-61 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 34989 XM_044309901.1 97 98 44 168 274 Q80XJ3 2.83e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 34990 XM_044309901.1 97 98 44 168 274 Q80XJ3 7.99e-57 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 34991 XM_044309901.1 97 98 44 168 274 Q80XJ3 2.71e-51 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 34992 XM_029343534.2 47 26 11 10 106 NA NA NA NA NA NA 34993 XM_044318297.1 45 46 24 15 61 NA NA NA NA NA NA 34994 XM_044327625.1 10 7 2 0 2 Q5R6J3 4.85e-109 Solute carrier family 35 member F5 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0016020 34995 XM_029338992.2 81 242 96 97 158 NA NA NA NA NA NA 34996 XM_044317777.1 358 320 184 514 667 NA NA NA NA NA NA 34997 XM_029337933.2 0 0 0 23 14 NA NA NA NA NA NA 34998 XM_044325794.1 0 7 0 0 0 NA NA NA NA NA NA 34999 XM_044311057.1 19 0 0 0 0 NA NA NA NA NA NA 35000 XM_044326793.1 1 1 18 0 16 NA NA NA NA NA NA 35001 XM_029345997.2 455 524 335 948 348 P53804 1.2e-41 E3 ubiquitin-protein ligase TTC3 (EC 2.3.2.27) (Protein DCRR1) (RING finger protein 105) (RING-type E3 ubiquitin transferase TTC3) (TPR repeat protein D) (Tetratricopeptide repeat protein 3) (TPR repeat protein 3) Homo sapiens (Human) protein K48-linked ubiquitination [GO:0070936]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004842; GO:0005634; GO:0005654; GO:0005730; GO:0005794; GO:0005829; GO:0006511; GO:0046872; GO:0070936 35002 XM_044327255.1 2038 1557 2254 2953 2409 Q3UZV7 5.56e-29 Endosome/lysosome-associated apoptosis and autophagy regulator family member 2 (Estrogen-induced gene 121-like protein) Mus musculus (Mouse) negative regulation of nervous system development [GO:0051961]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of epidermis development [GO:0045684] GO:0005886; GO:0016020; GO:0030513; GO:0045684; GO:0051961; GO:0070700 35003 XM_029329350.2 17366 15051 14247 21345 21913 A1L157 3.44e-34 Tetraspanin-11 (Tspan-11) Homo sapiens (Human) cell migration [GO:0016477] GO:0005886; GO:0016477 35004 XM_029331367.2 17 51 0 29 71 Q6P1S2 6.26e-21 Protein C3orf33 (Protein AC3-33) Homo sapiens (Human) negative regulation of ERK1 and ERK2 cascade [GO:0070373]; regulation of DNA-binding transcription factor activity [GO:0051090] GO:0005615; GO:0016020; GO:0051090; GO:0070373 35005 XM_044312354.1 0 0 10 0 1 NA NA NA NA NA NA 35006 XM_029326555.2 316 371 160 798 676 Q00685 8.97e-144 Complement C3 [Cleaved into: Complement C3 beta chain; Complement C3 alpha chain; C3a anaphylatoxin; Complement C3 gamma chain] Lethenteron camtschaticum (Japanese lamprey) (Lampetra japonica) complement activation, classical pathway [GO:0006958]; inflammatory response [GO:0006954]; innate immune response [GO:0045087] GO:0004866; GO:0005615; GO:0006954; GO:0006958; GO:0045087 35007 XM_029326555.2 316 371 160 798 676 Q00685 5.27e-24 Complement C3 [Cleaved into: Complement C3 beta chain; Complement C3 alpha chain; C3a anaphylatoxin; Complement C3 gamma chain] Lethenteron camtschaticum (Japanese lamprey) (Lampetra japonica) complement activation, classical pathway [GO:0006958]; inflammatory response [GO:0006954]; innate immune response [GO:0045087] GO:0004866; GO:0005615; GO:0006954; GO:0006958; GO:0045087 35008 XR_006396127.1 87 75 57 32 154 NA NA NA NA NA NA 35009 XM_029323631.2 347 29 644 119 1890 NA NA NA NA NA NA 35010 XM_044317169.1 196 0 0 77 0 A5D6U8 2.33e-99 Acid phosphatase type 7 (EC 3.1.3.2) (Purple acid phosphatase long form) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0003993; GO:0005576; GO:0046872 35011 XM_044319227.1 200 47 66 198 186 Q8N9H8 4.66e-95 Exonuclease mut-7 homolog (EC 3.1.-.-) (Exonuclease 3'-5' domain-containing protein 3) Homo sapiens (Human) NA GO:0003676; GO:0008408; GO:0046872 35012 XM_029354905.2 499 487 369 455 528 NA NA NA NA NA NA 35013 XM_044328349.1 24 605 446 551 43 P22105 1.18e-48 Tenascin-X (TN-X) (Hexabrachion-like protein) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; elastic fiber assembly [GO:0048251]; extracellular matrix organization [GO:0030198]; fatty acid metabolic process [GO:0006631]; positive regulation of cell fate determination [GO:1905935]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen fibril organization [GO:1904028]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of transforming growth factor beta activation [GO:1901390]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of cell migration [GO:0030334]; regulation of JUN kinase activity [GO:0043506]; triglyceride metabolic process [GO:0006641] GO:0005178; GO:0005201; GO:0005518; GO:0005576; GO:0005615; GO:0006631; GO:0006641; GO:0007155; GO:0007160; GO:0008201; GO:0008284; GO:0010718; GO:0010862; GO:0030036; GO:0030155; GO:0030198; GO:0030199; GO:0030334; GO:0030511; GO:0031012; GO:0032963; GO:0043506; GO:0045595; GO:0048251; GO:0062023; GO:0070062; GO:0090733; GO:0098609; GO:0098633; GO:1900748; GO:1901390; GO:1904028; GO:1905935 35014 XM_044328349.1 24 605 446 551 43 P22105 1.26e-44 Tenascin-X (TN-X) (Hexabrachion-like protein) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; elastic fiber assembly [GO:0048251]; extracellular matrix organization [GO:0030198]; fatty acid metabolic process [GO:0006631]; positive regulation of cell fate determination [GO:1905935]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen fibril organization [GO:1904028]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of transforming growth factor beta activation [GO:1901390]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of cell migration [GO:0030334]; regulation of JUN kinase activity [GO:0043506]; triglyceride metabolic process [GO:0006641] GO:0005178; GO:0005201; GO:0005518; GO:0005576; GO:0005615; GO:0006631; GO:0006641; GO:0007155; GO:0007160; GO:0008201; GO:0008284; GO:0010718; GO:0010862; GO:0030036; GO:0030155; GO:0030198; GO:0030199; GO:0030334; GO:0030511; GO:0031012; GO:0032963; GO:0043506; GO:0045595; GO:0048251; GO:0062023; GO:0070062; GO:0090733; GO:0098609; GO:0098633; GO:1900748; GO:1901390; GO:1904028; GO:1905935 35015 XM_044328349.1 24 605 446 551 43 P22105 2.07e-42 Tenascin-X (TN-X) (Hexabrachion-like protein) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; elastic fiber assembly [GO:0048251]; extracellular matrix organization [GO:0030198]; fatty acid metabolic process [GO:0006631]; positive regulation of cell fate determination [GO:1905935]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen fibril organization [GO:1904028]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of transforming growth factor beta activation [GO:1901390]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of cell migration [GO:0030334]; regulation of JUN kinase activity [GO:0043506]; triglyceride metabolic process [GO:0006641] GO:0005178; GO:0005201; GO:0005518; GO:0005576; GO:0005615; GO:0006631; GO:0006641; GO:0007155; GO:0007160; GO:0008201; GO:0008284; GO:0010718; GO:0010862; GO:0030036; GO:0030155; GO:0030198; GO:0030199; GO:0030334; GO:0030511; GO:0031012; GO:0032963; GO:0043506; GO:0045595; GO:0048251; GO:0062023; GO:0070062; GO:0090733; GO:0098609; GO:0098633; GO:1900748; GO:1901390; GO:1904028; GO:1905935 35016 XM_044328349.1 24 605 446 551 43 P22105 4.22e-32 Tenascin-X (TN-X) (Hexabrachion-like protein) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; elastic fiber assembly [GO:0048251]; extracellular matrix organization [GO:0030198]; fatty acid metabolic process [GO:0006631]; positive regulation of cell fate determination [GO:1905935]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen fibril organization [GO:1904028]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of transforming growth factor beta activation [GO:1901390]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of cell migration [GO:0030334]; regulation of JUN kinase activity [GO:0043506]; triglyceride metabolic process [GO:0006641] GO:0005178; GO:0005201; GO:0005518; GO:0005576; GO:0005615; GO:0006631; GO:0006641; GO:0007155; GO:0007160; GO:0008201; GO:0008284; GO:0010718; GO:0010862; GO:0030036; GO:0030155; GO:0030198; GO:0030199; GO:0030334; GO:0030511; GO:0031012; GO:0032963; GO:0043506; GO:0045595; GO:0048251; GO:0062023; GO:0070062; GO:0090733; GO:0098609; GO:0098633; GO:1900748; GO:1901390; GO:1904028; GO:1905935 35017 XM_044320524.1 93 5 31 11 54 A0A1L8FZ98 1.81e-67 Peroxisome biogenesis factor 2 (EC 2.3.2.27) (EC 2.3.2.36) (Peroxin-2) Xenopus laevis (African clawed frog) pexophagy [GO:0000425]; protein import into peroxisome matrix, receptor recycling [GO:0016562]; response to amino acid starvation [GO:1990928] GO:0000425; GO:0005778; GO:0016562; GO:0046872; GO:0061630; GO:1990928 35018 XR_006391463.1 38 48 18 21 31 NA NA NA NA NA NA 35019 XM_029341864.2 22 0 23 33 47 NA NA NA NA NA NA 35020 XM_044315837.1 175 116 296 163 619 NA NA NA NA NA NA 35021 XM_029351977.2 50 35 30 60 5 B1WC40 1.34e-63 Nuclear cap-binding protein subunit 2 (20 kDa nuclear cap-binding protein) (NCBP 20 kDa subunit) (CBP20) Rattus norvegicus (Rat) histone mRNA metabolic process [GO:0008334]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transcription by RNA polymerase II [GO:0042789]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of mRNA 3'-end processing [GO:0031442]; positive regulation of RNA export from nucleus [GO:0046833]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; regulation of translational initiation [GO:0006446]; RNA splicing [GO:0008380]; RNA-mediated gene silencing [GO:0031047]; snRNA export from nucleus [GO:0006408] GO:0000184; GO:0000339; GO:0000340; GO:0000398; GO:0003677; GO:0003729; GO:0005634; GO:0005737; GO:0005845; GO:0005846; GO:0006406; GO:0006408; GO:0006446; GO:0008334; GO:0008380; GO:0017069; GO:0031047; GO:0031442; GO:0034518; GO:0042789; GO:0045292; GO:0046833; GO:0098789 35022 XM_029338585.2 0 0 126 235 172 Q13976 0 cGMP-dependent protein kinase 1 (cGK 1) (cGK1) (EC 2.7.11.12) (cGMP-dependent protein kinase I) (cGKI) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cGMP-mediated signaling [GO:0019934]; collateral sprouting [GO:0048668]; dendrite development [GO:0016358]; forebrain development [GO:0030900]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; negative regulation of vascular associated smooth muscle cell proliferation [GO:1904706]; neuron migration [GO:0001764]; protein phosphorylation [GO:0006468]; regulation of GTPase activity [GO:0043087]; relaxation of vascular associated smooth muscle [GO:0060087]; signal transduction [GO:0007165] GO:0001764; GO:0004672; GO:0004692; GO:0005246; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005886; GO:0006468; GO:0007165; GO:0016358; GO:0019934; GO:0030036; GO:0030553; GO:0030900; GO:0042802; GO:0043087; GO:0048668; GO:0060087; GO:0090331; GO:0106310; GO:1904706; GO:1904753 35023 XM_044307275.1 82 38 33 48 48 NA NA NA NA NA NA 35024 XM_029350391.2 302 213 158 188 385 Q61006 5.73e-77 Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine-protein kinase receptor) (MuSK) (Muscle-specific kinase receptor) Mus musculus (Mouse) cell differentiation [GO:0030154]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; motor neuron apoptotic process [GO:0097049]; negative regulation of gene expression [GO:0010629]; neuromuscular junction development [GO:0007528]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of motor neuron apoptotic process [GO:2000673]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein geranylgeranylation [GO:2000541]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; positive regulation of synaptic assembly at neuromuscular junction [GO:0045887]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; protein autophosphorylation [GO:0046777]; receptor clustering [GO:0043113]; regulation of DNA-templated transcription [GO:0006355]; regulation of synaptic assembly at neuromuscular junction [GO:0008582]; response to electrical stimulus [GO:0051602]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0001934; GO:0004713; GO:0004714; GO:0005518; GO:0005524; GO:0005886; GO:0006355; GO:0007169; GO:0007528; GO:0007613; GO:0008582; GO:0009897; GO:0010628; GO:0010629; GO:0016020; GO:0019901; GO:0030154; GO:0030165; GO:0031594; GO:0032224; GO:0033674; GO:0038062; GO:0042995; GO:0043113; GO:0043235; GO:0045202; GO:0045211; GO:0045887; GO:0046777; GO:0046872; GO:0050731; GO:0051602; GO:0060291; GO:0071340; GO:0097049; GO:1904395; GO:2000541; GO:2000673 35025 XM_029338457.2 17 0 0 0 220 Q7K556 1.41e-147 TRPL translocation defect protein 14 Drosophila melanogaster (Fruit fly) photoreceptor cell maintenance [GO:0045494]; protein transport [GO:0015031] GO:0005525; GO:0005829; GO:0015031; GO:0035091; GO:0045494; GO:0070300 35026 XM_029358715.2 93 160 0 0 0 Q9GYZ0 0 Kinesin-like protein KIF15 (Kinesin-related protein KRP180) Strongylocentrotus purpuratus (Purple sea urchin) microtubule-based movement [GO:0007018]; regulation of mitotic spindle assembly [GO:1901673] GO:0003777; GO:0005524; GO:0005737; GO:0005819; GO:0005871; GO:0005874; GO:0007018; GO:0008017; GO:0016887; GO:1901673 35027 XM_044312749.1 60 52 0 0 0 Q17RS7 9.71e-67 Flap endonuclease GEN homolog 1 (EC 3.1.-.-) Homo sapiens (Human) double-strand break repair via homologous recombination [GO:0000724]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; regulation of centrosome duplication [GO:0010824]; replication fork processing [GO:0031297]; resolution of mitotic recombination intermediates [GO:0071140]; resolution of recombination intermediates [GO:0071139] GO:0000287; GO:0000400; GO:0000724; GO:0005654; GO:0005813; GO:0008821; GO:0010824; GO:0017108; GO:0031297; GO:0042803; GO:0071139; GO:0071140; GO:0090267 35028 XM_029343926.2 68 113 219 267 152 Q13360 8.19e-43 Zinc finger protein 177 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000977; GO:0000981; GO:0001227; GO:0005634; GO:0006357; GO:0046872; GO:0072562; GO:1990837 35029 XM_029343926.2 68 113 219 267 152 Q13360 2.09e-24 Zinc finger protein 177 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000977; GO:0000981; GO:0001227; GO:0005634; GO:0006357; GO:0046872; GO:0072562; GO:1990837 35030 XM_029336503.2 0 0 0 0 15 Q6DDJ5 1.59e-24 WD repeat and coiled-coil-containing protein Xenopus laevis (African clawed frog) NA NA 35031 XM_044322955.1 0 0 9 0 0 Q03701 0 CCAAT/enhancer-binding protein zeta (CCAAT-box-binding transcription factor) (CBF) (CCAAT-binding factor) Homo sapiens (Human) positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0003713; GO:0003723; GO:0005634; GO:0016602; GO:0045944 35032 XM_029333986.2 228 0 0 107 148 NA NA NA NA NA NA 35033 XM_029338701.2 787 788 549 1542 1153 O75116 0 Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, coiled-coil-containing protein kinase 2) (Rho-associated, coiled-coil-containing protein kinase II) (ROCK-II) (p164 ROCK-2) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; actomyosin structure organization [GO:0031032]; aortic valve morphogenesis [GO:0003180]; blood vessel diameter maintenance [GO:0097746]; cellular response to acetylcholine [GO:1905145]; cellular response to testosterone stimulus [GO:0071394]; centrosome duplication [GO:0051298]; cortical actin cytoskeleton organization [GO:0030866]; embryonic morphogenesis [GO:0048598]; epithelial to mesenchymal transition [GO:0001837]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; mitotic cytokinesis [GO:0000281]; modulation by host of viral process [GO:0044788]; mRNA destabilization [GO:0061157]; negative regulation of angiogenesis [GO:0016525]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of gene expression [GO:0010629]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of protein localization to lysosome [GO:0150033]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of amyloid precursor protein catabolic process [GO:1902993]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell migration [GO:0030335]; positive regulation of centrosome duplication [GO:0010825]; positive regulation of connective tissue growth factor production [GO:0032723]; positive regulation of connective tissue replacement [GO:1905205]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of stress fiber assembly [GO:0051496]; protein localization to plasma membrane [GO:0072659]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of angiotensin-activated signaling pathway [GO:0110061]; regulation of cell adhesion [GO:0030155]; regulation of cell junction assembly [GO:1901888]; regulation of cell motility [GO:2000145]; regulation of cellular response to hypoxia [GO:1900037]; regulation of circadian rhythm [GO:0042752]; regulation of establishment of cell polarity [GO:2000114]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of focal adhesion assembly [GO:0051893]; regulation of keratinocyte differentiation [GO:0045616]; regulation of nervous system process [GO:0031644]; regulation of protein metabolic process [GO:0051246]; regulation of stress fiber assembly [GO:0051492]; response to angiotensin [GO:1990776]; response to ischemia [GO:0002931]; response to transforming growth factor beta [GO:0071559]; Rho protein signal transduction [GO:0007266]; rhythmic process [GO:0048511]; smooth muscle contraction [GO:0006939] GO:0000281; GO:0001837; GO:0001934; GO:0002931; GO:0003180; GO:0003723; GO:0004674; GO:0005198; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0005856; GO:0005886; GO:0006468; GO:0006939; GO:0007249; GO:0007266; GO:0010595; GO:0010613; GO:0010628; GO:0010629; GO:0010825; GO:0016525; GO:0018105; GO:0018107; GO:0030036; GO:0030155; GO:0030335; GO:0030866; GO:0031032; GO:0031267; GO:0031644; GO:0032723; GO:0032956; GO:0035509; GO:0036464; GO:0042752; GO:0043410; GO:0044788; GO:0045019; GO:0045616; GO:0046872; GO:0048156; GO:0048511; GO:0048598; GO:0050321; GO:0051246; GO:0051298; GO:0051492; GO:0051496; GO:0051893; GO:0061157; GO:0070168; GO:0071394; GO:0071559; GO:0072518; GO:0072659; GO:0090271; GO:0097746; GO:0106310; GO:0110061; GO:0150033; GO:1900037; GO:1901888; GO:1902004; GO:1902961; GO:1902966; GO:1902993; GO:1903140; GO:1903347; GO:1905145; GO:1905205; GO:1990776; GO:2000114; GO:2000145 35034 XM_029340241.2 7529 5865 5129 5608 4588 Q6FRC6 3.21e-32 Nuclear transport factor 2 (NTF-2) Candida glabrata (Yeast) (Torulopsis glabrata) protein import into nucleus [GO:0006606] GO:0005635; GO:0005737; GO:0006606; GO:0031267 35035 XM_044325861.1 28 57 25 102 44 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35036 XM_044325861.1 28 57 25 102 44 Q96AY4 2.34e-165 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35037 XM_044325861.1 28 57 25 102 44 Q96AY4 3.24e-108 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35038 XM_044325861.1 28 57 25 102 44 Q96AY4 6.77e-77 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35039 XM_044325861.1 28 57 25 102 44 Q96AY4 7.83e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35040 XM_029348785.2 0 58 10 474 186 Q9BZ29 0 Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin-1) (Zizimin-1) Homo sapiens (Human) positive regulation of GTPase activity [GO:0043547]; small GTPase mediated signal transduction [GO:0007264] GO:0005085; GO:0005829; GO:0007264; GO:0012505; GO:0016020; GO:0043547; GO:0045296 35041 XM_044321766.1 722 835 310 713 2034 Q5R4J5 4.51e-21 Synaptotagmin-1 (Synaptotagmin I) (SytI) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cell differentiation [GO:0030154]; positive regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903235] GO:0030154; GO:0030672; GO:0042584; GO:0046872; GO:1903235 35042 XR_006392350.1 96 56 211 272 39 Q99570 0 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 35043 XR_006392350.1 96 56 211 272 39 Q99570 0 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 35044 XR_006392350.1 96 56 211 272 39 Q99570 0 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 35045 XR_006392350.1 96 56 211 272 39 Q99570 0 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 35046 XM_044316915.1 754 427 375 517 783 Q8WML3 3.35e-141 Histone acetyltransferase KAT6B (EC 2.3.1.48) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (MYST-4) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) histone acetylation [GO:0016573]; negative regulation of DNA-templated transcription [GO:0045892]; nucleosome assembly [GO:0006334]; positive regulation of DNA-templated transcription [GO:0045893] GO:0000786; GO:0003677; GO:0003713; GO:0004402; GO:0005634; GO:0006334; GO:0016573; GO:0045892; GO:0045893; GO:0046872; GO:0061733; GO:0070776 35047 XM_044316915.1 754 427 375 517 783 Q8WML3 2.68e-65 Histone acetyltransferase KAT6B (EC 2.3.1.48) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (MYST-4) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) histone acetylation [GO:0016573]; negative regulation of DNA-templated transcription [GO:0045892]; nucleosome assembly [GO:0006334]; positive regulation of DNA-templated transcription [GO:0045893] GO:0000786; GO:0003677; GO:0003713; GO:0004402; GO:0005634; GO:0006334; GO:0016573; GO:0045892; GO:0045893; GO:0046872; GO:0061733; GO:0070776 35048 XM_029333560.2 31 8 14 33 18 NA NA NA NA NA NA 35049 XM_044321688.1 0 10 0 0 25 Q5RGV1 0 Inosine-5'-monophosphate dehydrogenase 1b (IMP dehydrogenase 1b) (IMPD 1b) (IMPDH 1b) (EC 1.1.1.205) Danio rerio (Zebrafish) (Brachydanio rerio) GMP biosynthetic process [GO:0006177]; GTP biosynthetic process [GO:0006183] GO:0000166; GO:0003938; GO:0005634; GO:0005737; GO:0006177; GO:0006183; GO:0046872 35050 XM_044325207.1 23 0 0 0 0 NA NA NA NA NA NA 35051 XM_044309150.1 89 178 114 65 158 C3YZ51 1.36e-170 Ubiquitin-like modifier-activating enzyme 5 (Ubiquitin-activating enzyme 5) Branchiostoma floridae (Florida lancelet) (Amphioxus) protein modification by small protein conjugation [GO:0032446]; protein ufmylation [GO:0071569] GO:0005524; GO:0005737; GO:0005829; GO:0032446; GO:0046872; GO:0071566; GO:0071569 35052 XM_044310133.1 19 101 0 29 17 Q9Y6N7 9.51e-31 Roundabout homolog 1 (Deleted in U twenty twenty) (H-Robo-1) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; axon midline choice point recognition [GO:0016199]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; endocardial cushion formation [GO:0003272]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of gene expression [GO:0010629]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; negative regulation of negative chemotaxis [GO:0050925]; nervous system development [GO:0007399]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; pulmonary valve morphogenesis [GO:0003184]; Roundabout signaling pathway [GO:0035385]; ventricular septum morphogenesis [GO:0060412] GO:0002042; GO:0003148; GO:0003180; GO:0003184; GO:0003272; GO:0005737; GO:0005886; GO:0006919; GO:0007155; GO:0007156; GO:0007399; GO:0008046; GO:0009986; GO:0010628; GO:0010629; GO:0016199; GO:0021836; GO:0030275; GO:0030336; GO:0030424; GO:0033116; GO:0033600; GO:0035025; GO:0035385; GO:0035481; GO:0035904; GO:0042802; GO:0043406; GO:0050772; GO:0050925; GO:0060412; GO:0070100; GO:1900748 35053 XM_044310133.1 19 101 0 29 17 Q9Y6N7 1.32e-21 Roundabout homolog 1 (Deleted in U twenty twenty) (H-Robo-1) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; axon midline choice point recognition [GO:0016199]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; endocardial cushion formation [GO:0003272]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of gene expression [GO:0010629]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; negative regulation of negative chemotaxis [GO:0050925]; nervous system development [GO:0007399]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; pulmonary valve morphogenesis [GO:0003184]; Roundabout signaling pathway [GO:0035385]; ventricular septum morphogenesis [GO:0060412] GO:0002042; GO:0003148; GO:0003180; GO:0003184; GO:0003272; GO:0005737; GO:0005886; GO:0006919; GO:0007155; GO:0007156; GO:0007399; GO:0008046; GO:0009986; GO:0010628; GO:0010629; GO:0016199; GO:0021836; GO:0030275; GO:0030336; GO:0030424; GO:0033116; GO:0033600; GO:0035025; GO:0035385; GO:0035481; GO:0035904; GO:0042802; GO:0043406; GO:0050772; GO:0050925; GO:0060412; GO:0070100; GO:1900748 35054 XR_006397963.1 77 32 33 73 54 O08696 4.97e-25 Forkhead box protein M1 (Forkhead homolog 16) (Winged-helix transcription factor Trident) Mus musculus (Mouse) cell population proliferation [GO:0008283]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA repair [GO:0006281]; G2/M transition of mitotic cell cycle [GO:0000086]; liver development [GO:0001889]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of Ras protein signal transduction [GO:0046578]; regulation of reactive oxygen species metabolic process [GO:2000377]; regulation of transcription by RNA polymerase II [GO:0006357]; stem cell proliferation [GO:0072089]; vasculogenesis [GO:0001570] GO:0000086; GO:0000122; GO:0000976; GO:0000977; GO:0001570; GO:0001889; GO:0003677; GO:0003700; GO:0005634; GO:0006281; GO:0006357; GO:0006978; GO:0008283; GO:0008284; GO:0019901; GO:0032873; GO:0042127; GO:0043565; GO:0045892; GO:0045893; GO:0045944; GO:0046578; GO:0051726; GO:0072089; GO:2000377; GO:2000648; GO:2000781 35055 XM_029345147.2 134 105 118 249 40 NA NA NA NA NA NA 35056 XR_006398018.1 2 1 6 4 7 NA NA NA NA NA NA 35057 XM_044322868.1 253 153 334 570 38 Q9NZJ4 0 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 35058 XM_044322868.1 253 153 334 570 38 Q9NZJ4 1.02e-41 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 35059 XM_044313142.1 182 462 132 253 644 Q9NYG2 4.9e-48 Palmitoyltransferase ZDHHC3 (EC 2.3.1.225) (Acyltransferase ZDHHC3) (EC 2.3.1.-) (Protein DHHC1) (Zinc finger DHHC domain-containing protein 3) (DHHC-3) Homo sapiens (Human) lipoprotein localization to membrane [GO:0044873]; peptidyl-L-cysteine S-palmitoylation [GO:0018230]; positive regulation of receptor localization to synapse [GO:1902685]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; protein localization to photoreceptor outer segment [GO:1903546]; protein localization to plasma membrane [GO:0072659]; protein palmitoylation [GO:0018345]; protein targeting to membrane [GO:0006612]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; TRAIL-activated apoptotic signaling pathway [GO:0036462] GO:0000139; GO:0005783; GO:0005794; GO:0006612; GO:0008277; GO:0016020; GO:0016409; GO:0018230; GO:0018345; GO:0019705; GO:0019706; GO:0032230; GO:0036462; GO:0042803; GO:0044873; GO:0072659; GO:0140439; GO:1902685; GO:1903546 35060 XM_044327247.1 0 64 101 0 0 Q9UBD5 0 Origin recognition complex subunit 3 (Origin recognition complex subunit Latheo) Homo sapiens (Human) DNA replication [GO:0006260]; DNA replication initiation [GO:0006270]; glial cell proliferation [GO:0014009]; neural precursor cell proliferation [GO:0061351]; regulation of DNA replication [GO:0006275] GO:0000781; GO:0000785; GO:0000808; GO:0003688; GO:0005654; GO:0005656; GO:0005664; GO:0006260; GO:0006270; GO:0006275; GO:0014009; GO:0016604; GO:0031261; GO:0061351 35061 XM_029348600.2 905 0 0 179 1287 Q5ZJZ6 0 Nuclear cap-binding protein subunit 1 (80 kDa nuclear cap-binding protein) (CBP80) (NCBP 80 kDa subunit) Gallus gallus (Chicken) 7-methylguanosine mRNA capping [GO:0006370]; mRNA export from nucleus [GO:0006406]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of mRNA processing [GO:0050684]; regulation of translational initiation [GO:0006446]; RNA splicing [GO:0008380]; RNA-mediated gene silencing [GO:0031047] GO:0000184; GO:0000339; GO:0003729; GO:0005634; GO:0005737; GO:0005845; GO:0005846; GO:0006370; GO:0006406; GO:0006446; GO:0008380; GO:0031047; GO:0050684 35062 XM_029349129.2 0 31 0 0 71 Q6NRC9 0 Leucine-rich repeat and coiled-coil domain-containing protein 1 Xenopus laevis (African clawed frog) cell cycle [GO:0007049]; cell division [GO:0051301] GO:0005737; GO:0005814; GO:0007049; GO:0051301 35063 XM_044310801.1 24 20 26 24 62 NA NA NA NA NA NA 35064 XM_029357151.2 66 40 96 20 370 A0A2R8Q1W5 2.36e-38 Kelch-like ECH-associated protein 1B Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to oxidative stress [GO:0034599]; cellular response to prostaglandin stimulus [GO:0071379]; cellular response to xenobiotic stimulus [GO:0071466]; protein ubiquitination [GO:0016567]; regulation of autophagy [GO:0010506]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0005634; GO:0005737; GO:0006511; GO:0010506; GO:0016234; GO:0016567; GO:0034599; GO:0071379; GO:0071466 35065 XM_044310040.1 20 0 0 3 4 O46640 3.34e-55 Amine sulfotransferase (EC 2.8.2.3) (AST-RB1) (Sulfotransferase 3A1) (ST3A1) Oryctolagus cuniculus (Rabbit) NA GO:0005737; GO:0047685 35066 XM_044328903.1 453 126 436 321 540 Q80ZA4 0 Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86) Mus musculus (Mouse) sensory perception of sound [GO:0007605] GO:0007605; GO:0016020; GO:0032426; GO:0120234 35067 XM_029358223.2 745 94 392 492 396 Q68D06 9.63e-60 Schlafen family member 13 (EC 3.1.-.-) (Schlafen-13) (hSLFN13) Homo sapiens (Human) defense response to virus [GO:0051607]; rRNA catabolic process [GO:0016075]; tRNA catabolic process [GO:0016078] GO:0000049; GO:0004521; GO:0005524; GO:0005737; GO:0008270; GO:0016075; GO:0016078; GO:0051607 35068 XM_029344291.2 0 0 36 242 314 B3DK16 2.2e-75 Polycomb group RING finger protein 5-A Danio rerio (Zebrafish) (Brachydanio rerio) histone H2A-K119 monoubiquitination [GO:0036353]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0006357; GO:0031519; GO:0035102; GO:0036353; GO:0046872 35069 XM_029335275.2 209 131 137 377 81 Q26636 1.17e-130 Cathepsin L (EC 3.4.22.15) [Cleaved into: Cathepsin L heavy chain; Cathepsin L light chain] Sarcophaga peregrina (Flesh fly) (Boettcherisca peregrina) cell differentiation [GO:0030154]; proteolysis [GO:0006508] GO:0004197; GO:0005764; GO:0006508; GO:0030154 35070 XM_044311746.1 250 184 109 170 195 A8WG43 6.9e-44 Coiled-coil domain-containing protein 89 (Bc8 orange-interacting protein) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005634; GO:0005737 35071 XM_044324759.1 35 0 2 16 56 NA NA NA NA NA NA 35072 XM_044312858.1 144 52 57 108 89 A4IF93 7.78e-152 TBCC domain-containing protein 1 Bos taurus (Bovine) maintenance of centrosome location [GO:0051661]; maintenance of Golgi location [GO:0051684]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360] GO:0005737; GO:0008360; GO:0030334; GO:0031616; GO:0051661; GO:0051684 35073 XM_044329328.1 14 22 0 5 28 Q9BUZ4 5.26e-66 TNF receptor-associated factor 4 (EC 2.3.2.27) (Cysteine-rich domain associated with RING and Traf domains protein 1) (Metastatic lymph node gene 62 protein) (MLN 62) (RING finger protein 83) Homo sapiens (Human) activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; innate immune response [GO:0045087]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein kinase activity [GO:0045860]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; respiratory gaseous exchange by respiratory system [GO:0007585]; respiratory tube development [GO:0030323] GO:0001650; GO:0005164; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0005923; GO:0006915; GO:0007250; GO:0007585; GO:0008270; GO:0016740; GO:0019901; GO:0030323; GO:0031625; GO:0031996; GO:0042802; GO:0042981; GO:0043122; GO:0043161; GO:0045087; GO:0045860; GO:0046330; GO:0048471; GO:0050699 35074 XM_029358727.2 260 142 81 244 408 Q5XIA9 1.11e-24 Kelch domain-containing protein 8B Rattus norvegicus (Rat) mitotic cytokinetic process [GO:1902410]; mitotic nuclear division [GO:0140014]; nuclear chromosome segregation [GO:0098813] GO:0005737; GO:0030496; GO:0045171; GO:0098813; GO:0110070; GO:0140014; GO:1902410 35075 XM_044306980.1 1138 521 811 0 704 Q6V0I7 1.43e-58 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 35076 XM_044306980.1 1138 521 811 0 704 Q6V0I7 1.55e-55 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 35077 XM_044306980.1 1138 521 811 0 704 Q6V0I7 3.99e-43 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 35078 XM_044306980.1 1138 521 811 0 704 Q6V0I7 1.25e-40 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 35079 XM_044306980.1 1138 521 811 0 704 Q6V0I7 4.7e-40 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 35080 XM_044306980.1 1138 521 811 0 704 Q6V0I7 2.52e-39 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 35081 XM_044306980.1 1138 521 811 0 704 Q6V0I7 3.16e-35 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 35082 XM_044306980.1 1138 521 811 0 704 Q6V0I7 6.64e-29 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 35083 XM_044306980.1 1138 521 811 0 704 Q6V0I7 1.86e-26 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 35084 XM_044306980.1 1138 521 811 0 704 Q6V0I7 5.18e-26 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 35085 XM_044306980.1 1138 521 811 0 704 Q6V0I7 2.46e-23 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 35086 XR_006396154.1 0 0 0 0 20 NA NA NA NA NA NA 35087 XM_044326348.1 4081 125 101 1645 2929 R1CW23 1.62e-109 Dimethylsulfonioproprionate lyase 7 (DMSP lyase 7) (EC 4.4.1.3) (Dimethylpropiothetin dethiomethylase 7) Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi) NA GO:0047869 35088 XM_029358575.2 299 50 0 0 0 Q9R088 3.04e-62 Thymidine kinase 2, mitochondrial (EC 2.7.1.21) (2'-deoxyuridine kinase TK2) (EC 2.7.1.74) (Deoxycytidine kinase TK2) (EC 2.7.1.-) (Mt-TK) Mus musculus (Mouse) deoxycytidine metabolic process [GO:0046092]; deoxyribonucleotide metabolic process [GO:0009262]; DNA biosynthetic process [GO:0071897]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA replication [GO:0006264]; phosphorylation [GO:0016310]; thymidine metabolic process [GO:0046104] GO:0004137; GO:0004797; GO:0005524; GO:0005737; GO:0005739; GO:0005743; GO:0006264; GO:0009262; GO:0016310; GO:0019136; GO:0032042; GO:0046092; GO:0046104; GO:0071897 35089 XM_044314199.1 204 0 0 101 119 P70195 6.31e-33 Proteasome subunit beta type-7 (EC 3.4.25.1) (Macropain chain Z) (Multicatalytic endopeptidase complex chain Z) (Proteasome subunit Z) Mus musculus (Mouse) proteasomal protein catabolic process [GO:0010498] GO:0000502; GO:0004175; GO:0004298; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005839; GO:0010498; GO:0016604; GO:0019774 35090 XM_044314199.1 204 0 0 101 119 P70195 6.31e-33 Proteasome subunit beta type-7 (EC 3.4.25.1) (Macropain chain Z) (Multicatalytic endopeptidase complex chain Z) (Proteasome subunit Z) Mus musculus (Mouse) proteasomal protein catabolic process [GO:0010498] GO:0000502; GO:0004175; GO:0004298; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005839; GO:0010498; GO:0016604; GO:0019774 35091 XM_044314199.1 204 0 0 101 119 P70195 6.31e-33 Proteasome subunit beta type-7 (EC 3.4.25.1) (Macropain chain Z) (Multicatalytic endopeptidase complex chain Z) (Proteasome subunit Z) Mus musculus (Mouse) proteasomal protein catabolic process [GO:0010498] GO:0000502; GO:0004175; GO:0004298; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005839; GO:0010498; GO:0016604; GO:0019774 35092 XM_044318719.1 7 335 62 140 51 NA NA NA NA NA NA 35093 XM_029337905.2 610 140 287 466 445 NA NA NA NA NA NA 35094 XR_006394376.1 28 11 27 36 57 NA NA NA NA NA NA 35095 XM_029335809.2 704 642 365 685 655 NA NA NA NA NA NA 35096 XM_044307625.1 102 16 66 71 72 Q9GZX3 1.56e-25 Carbohydrate sulfotransferase 6 (Corneal N-acetylglucosamine-6-O-sulfotransferase) (C-GlcNAc6ST) (hCGn6ST) (EC 2.8.2.21) (Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 4-beta) (GST4-beta) (N-acetylglucosamine 6-O-sulfotransferase 5) (GlcNAc6ST-5) (Gn6st-5) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; keratan sulfate biosynthetic process [GO:0018146]; N-acetylglucosamine metabolic process [GO:0006044]; sulfur compound metabolic process [GO:0006790] GO:0000139; GO:0001517; GO:0005794; GO:0005802; GO:0005975; GO:0006044; GO:0006790; GO:0018146; GO:0045130 35097 XM_029343640.2 295 147 126 282 435 NA NA NA NA NA NA 35098 XM_044311661.1 99 104 29 27 0 Q9H2P9 1.28e-96 Diphthine methyl ester synthase (EC 2.1.1.314) (Diphthamide biosynthesis methyltransferase) Homo sapiens (Human) methylation [GO:0032259]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183] GO:0004164; GO:0005829; GO:0017183; GO:0032259 35099 XM_044327762.1 245 141 127 52 134 NA NA NA NA NA NA 35100 XR_003824814.2 0 10 0 131 2 NA NA NA NA NA NA 35101 XM_044309307.1 16 6 20 11 20 NA NA NA NA NA NA 35102 XM_029356184.2 0 24 0 0 0 Q9GJS9 1.78e-59 Glycine receptor subunit beta (Glycine receptor 58 kDa subunit) Bos taurus (Bovine) acrosome reaction [GO:0007340]; adult walking behavior [GO:0007628]; chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid receptor clustering [GO:0097112]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; nervous system development [GO:0007399]; nervous system process [GO:0050877]; neuropeptide signaling pathway [GO:0007218]; regulation of membrane potential [GO:0042391]; response to amino acid [GO:0043200]; righting reflex [GO:0060013]; signal transduction [GO:0007165]; startle response [GO:0001964]; synaptic transmission, glycinergic [GO:0060012]; visual perception [GO:0007601] GO:0001964; GO:0004888; GO:0005231; GO:0005737; GO:0005886; GO:0006811; GO:0007165; GO:0007218; GO:0007268; GO:0007340; GO:0007399; GO:0007601; GO:0007628; GO:0016594; GO:0016933; GO:0016934; GO:0016935; GO:0030425; GO:0030594; GO:0034220; GO:0042391; GO:0043005; GO:0043200; GO:0045202; GO:0045211; GO:0050877; GO:0060012; GO:0060013; GO:0097112; GO:0098690; GO:0098982; GO:1902476; GO:1904315 35103 XM_029342005.2 89 46 24 101 45 P23034 4.38e-50 Aspartate aminotransferase (AspAT) (EC 2.6.1.1) (Transaminase A) Bacillus sp. (strain YM-2) biosynthetic process [GO:0009058] GO:0004069; GO:0005737; GO:0009058; GO:0030170 35104 XM_044308508.1 53 15 12 11 10 Q6AZB8 2.16e-61 Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0004518; GO:0005634; GO:0005737; GO:0046872 35105 XM_029340058.2 92 87 27 48 38 P83852 1.03e-149 Carboxypeptidase D (EC 3.4.17.22) (CPD-2) (Metallocarboxypeptidase D) Lophonetta specularioides (Crested duck) (Anas specularioides) proteolysis [GO:0006508] GO:0004181; GO:0006508; GO:0008270; GO:0016020 35106 XR_006395694.1 0 2 2 8 0 NA NA NA NA NA NA 35107 XM_044321929.1 163 124 98 128 286 NA NA NA NA NA NA 35108 XM_044310339.1 0 0 3 6 11 NA NA NA NA NA NA 35109 XM_044323060.1 239 7 0 9 135 NA NA NA NA NA NA 35110 XM_044312808.1 0 0 4 0 65 Q17RS7 5.42e-51 Flap endonuclease GEN homolog 1 (EC 3.1.-.-) Homo sapiens (Human) double-strand break repair via homologous recombination [GO:0000724]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; regulation of centrosome duplication [GO:0010824]; replication fork processing [GO:0031297]; resolution of mitotic recombination intermediates [GO:0071140]; resolution of recombination intermediates [GO:0071139] GO:0000287; GO:0000400; GO:0000724; GO:0005654; GO:0005813; GO:0008821; GO:0010824; GO:0017108; GO:0031297; GO:0042803; GO:0071139; GO:0071140; GO:0090267 35111 XM_044311956.1 13 14 11 5 20 Q19546 1.43e-32 ATP-dependent helicase wrn-1 (EC 3.6.4.12) (Werner syndrome protein homolog) Caenorhabditis elegans determination of adult lifespan [GO:0008340]; DNA duplex unwinding [GO:0032508]; DNA metabolic process [GO:0006259]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724]; G-quadruplex DNA unwinding [GO:0044806]; multicellular organism aging [GO:0010259]; response to ionizing radiation [GO:0010212]; telomere maintenance [GO:0000723] GO:0000723; GO:0000724; GO:0003677; GO:0005524; GO:0005634; GO:0005654; GO:0005694; GO:0005737; GO:0006259; GO:0006268; GO:0006281; GO:0006310; GO:0008340; GO:0009378; GO:0010212; GO:0010259; GO:0016887; GO:0032508; GO:0035861; GO:0043138; GO:0044806 35112 XM_044311956.1 13 14 11 5 20 Q19546 1.43e-32 ATP-dependent helicase wrn-1 (EC 3.6.4.12) (Werner syndrome protein homolog) Caenorhabditis elegans determination of adult lifespan [GO:0008340]; DNA duplex unwinding [GO:0032508]; DNA metabolic process [GO:0006259]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724]; G-quadruplex DNA unwinding [GO:0044806]; multicellular organism aging [GO:0010259]; response to ionizing radiation [GO:0010212]; telomere maintenance [GO:0000723] GO:0000723; GO:0000724; GO:0003677; GO:0005524; GO:0005634; GO:0005654; GO:0005694; GO:0005737; GO:0006259; GO:0006268; GO:0006281; GO:0006310; GO:0008340; GO:0009378; GO:0010212; GO:0010259; GO:0016887; GO:0032508; GO:0035861; GO:0043138; GO:0044806 35113 XM_029356653.2 53 215 31 62 43 P19491 1.21e-80 Glutamate receptor 2 (GluR-2) (AMPA-selective glutamate receptor 2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (GluA2) Rattus norvegicus (Rat) cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to glycine [GO:1905430]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226] GO:0000149; GO:0001540; GO:0001919; GO:0004970; GO:0004971; GO:0005234; GO:0005783; GO:0005789; GO:0005886; GO:0007268; GO:0008021; GO:0008092; GO:0008328; GO:0009986; GO:0010226; GO:0014069; GO:0015276; GO:0015277; GO:0016020; GO:0019865; GO:0019901; GO:0021987; GO:0030165; GO:0030424; GO:0030425; GO:0030426; GO:0030672; GO:0031623; GO:0032279; GO:0032281; GO:0032590; GO:0032839; GO:0032991; GO:0035235; GO:0035254; GO:0035255; GO:0036477; GO:0038023; GO:0042734; GO:0042802; GO:0043005; GO:0043025; GO:0043195; GO:0043197; GO:0043198; GO:0043204; GO:0044326; GO:0044327; GO:0045184; GO:0045202; GO:0045211; GO:0048787; GO:0050806; GO:0051117; GO:0051262; GO:0051966; GO:0060992; GO:0097060; GO:0097110; GO:0098685; GO:0098793; GO:0098839; GO:0098978; GO:0099507; GO:0099544; GO:0106033; GO:1904315; GO:1905430; GO:1990416 35114 XM_044310658.1 4 34 9 0 9 P04323 1.01e-44 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 35115 XM_029356676.2 808 589 1328 1794 1200 NA NA NA NA NA NA 35116 XM_044319574.1 0 0 19 0 22 O94762 0 ATP-dependent DNA helicase Q5 (EC 3.6.4.12) (DNA helicase, RecQ-like type 5) (RecQ5) (RecQ protein-like 5) Homo sapiens (Human) cell division [GO:0051301]; cellular response to camptothecin [GO:0072757]; cellular response to ketone [GO:1901655]; cellular response to xenobiotic stimulus [GO:0071466]; chromosome separation [GO:0051304]; DNA duplex unwinding [GO:0032508]; DNA metabolic process [GO:0006259]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724]; mitotic cell cycle [GO:0000278]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; negative regulation of transcription elongation by RNA polymerase II [GO:0034244]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414] GO:0000278; GO:0000724; GO:0000993; GO:0003676; GO:0003678; GO:0005524; GO:0005634; GO:0005654; GO:0005694; GO:0005737; GO:0005829; GO:0006259; GO:0006260; GO:0006268; GO:0006281; GO:0006310; GO:0009378; GO:0016591; GO:0016887; GO:0032508; GO:0034244; GO:0042802; GO:0043138; GO:0051301; GO:0051304; GO:0071466; GO:0072757; GO:1901655; GO:1990414; GO:2000042 35117 XM_029357796.2 0 14 0 37 0 Q9EQD2 2.68e-46 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 35118 XM_044318150.1 472 290 210 407 428 Q8BLA8 1.58e-126 Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Wasabi receptor) Mus musculus (Mouse) calcium ion transmembrane import into cytosol [GO:0097553]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cell surface receptor signaling pathway [GO:0007166]; cellular calcium ion homeostasis [GO:0006874]; cellular response to carbon dioxide [GO:0071244]; cellular response to cold [GO:0070417]; cellular response to heat [GO:0034605]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to organic substance [GO:0071310]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; positive regulation of anion transport [GO:1903793]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of sensory perception of pain [GO:1904058]; protein homotetramerization [GO:0051289]; regulation of blood circulation [GO:1903522]; regulation of neuronal action potential [GO:0098908]; response to cold [GO:0009409]; response to hydrogen peroxide [GO:0042542]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; sensory perception of pain [GO:0019233]; thermoception [GO:0050955]; urinary bladder smooth muscle contraction [GO:0014832] GO:0005216; GO:0005245; GO:0005262; GO:0005886; GO:0006816; GO:0006874; GO:0007166; GO:0009409; GO:0009410; GO:0010033; GO:0014070; GO:0014832; GO:0015267; GO:0015278; GO:0016020; GO:0016324; GO:0019233; GO:0030424; GO:0032421; GO:0034605; GO:0035774; GO:0042542; GO:0042802; GO:0048265; GO:0050955; GO:0050966; GO:0050968; GO:0050974; GO:0051289; GO:0070301; GO:0070417; GO:0070588; GO:0071244; GO:0071310; GO:0097553; GO:0097604; GO:0098908; GO:1903522; GO:1903793; GO:1904058; GO:1990760 35119 XM_044317165.1 225 65 75 70 124 Q8CGC6 4.78e-33 RNA-binding protein 28 (RNA-binding motif protein 28) Mus musculus (Mouse) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0003723; GO:0005681; GO:0005730; GO:0006397; GO:0008380 35120 XM_029344213.2 248 251 212 135 129 Q9I8I2 4.47e-23 Bcl-2-related ovarian killer protein Gallus gallus (Chicken) extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; regulation of apoptotic process [GO:0042981] GO:0005741; GO:0008630; GO:0042803; GO:0042981; GO:0046982; GO:0097192 35121 XM_029334293.2 0 12 14 31 7 NA NA NA NA NA NA 35122 XM_029331431.2 496 668 344 588 412 Q6AYY8 0 Acetyl-coenzyme A transporter 1 (AT-1) (Acetyl-CoA transporter 1) (Solute carrier family 33 member 1) Rattus norvegicus (Rat) BMP signaling pathway [GO:0030509]; central nervous system development [GO:0007417]; SMAD protein signal transduction [GO:0060395] GO:0005789; GO:0007417; GO:0008521; GO:0015295; GO:0030509; GO:0060395 35123 XM_029330506.2 391 194 197 201 176 O95149 3.9e-109 Snurportin-1 (RNA U transporter 1) Homo sapiens (Human) protein import into nucleus [GO:0006606]; RNA import into nucleus [GO:0006404]; snRNA import into nucleus [GO:0061015] GO:0000339; GO:0005643; GO:0005654; GO:0005829; GO:0006404; GO:0006606; GO:0042564; GO:0061015; GO:0061608 35124 XM_044309438.1 490 407 462 508 325 Q6AXK4 2.66e-46 BRISC and BRCA1-A complex member 1 (Mediator of RAP80 interactions and targeting subunit of 40 kDa) (New component of the BRCA1-A complex) Danio rerio (Zebrafish) (Brachydanio rerio) cell division [GO:0051301]; chromatin organization [GO:0006325]; double-strand break repair [GO:0006302]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; positive regulation of DNA repair [GO:0045739]; protein K63-linked deubiquitination [GO:0070536]; response to ionizing radiation [GO:0010212] GO:0005634; GO:0005737; GO:0006302; GO:0006325; GO:0007095; GO:0010212; GO:0016604; GO:0045739; GO:0051301; GO:0070531; GO:0070536; GO:0070552 35125 XM_029356934.2 859 173 272 269 218 Q8NEE6 2.92e-166 Dynein regulatory complex subunit 6 (F-box and leucine-rich repeat protein 13) (F-box/LRR-repeat protein 13) Homo sapiens (Human) SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0005829; GO:0005856; GO:0019005; GO:0031146; GO:0031514 35126 XM_044328177.1 2081 1104 1288 2600 1823 O75581 0 Low-density lipoprotein receptor-related protein 6 (LRP-6) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; chemical synaptic transmission [GO:0007268]; dopaminergic neuron differentiation [GO:0071542]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001933; GO:0005041; GO:0005102; GO:0005109; GO:0005576; GO:0005783; GO:0005886; GO:0006469; GO:0007204; GO:0007268; GO:0009986; GO:0014029; GO:0014033; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0031410; GO:0031901; GO:0034392; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043434; GO:0044335; GO:0044340; GO:0045121; GO:0045202; GO:0045787; GO:0045893; GO:0045944; GO:0051091; GO:0060070; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072659; GO:0090118; GO:0090244; GO:0098609; GO:1904928; GO:1904948; GO:1904953; GO:1990851; GO:1990909 35127 XM_029327762.2 0 28 9 25 2 NA NA NA NA NA NA 35128 XR_003826553.2 0 0 2 0 18 NA NA NA NA NA NA 35129 XM_044320447.1 99 238 128 77 91 Q6F6U3 1.47e-31 NA NA NA NA 35130 XM_029335348.2 366 97 115 0 0 Q7SY06 2.49e-74 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase (EC 4.2.1.134) (3-hydroxyacyl-CoA dehydratase) (HACD) (Protein-tyrosine phosphatase-like A domain-containing protein 1) Danio rerio (Zebrafish) (Brachydanio rerio) fatty acid elongation [GO:0030497]; sphingolipid biosynthetic process [GO:0030148]; very long-chain fatty acid biosynthetic process [GO:0042761] GO:0005783; GO:0005789; GO:0018812; GO:0030148; GO:0030497; GO:0042761; GO:0102158; GO:0102343; GO:0102344; GO:0102345 35131 XM_044327188.1 35 23 24 5 60 NA NA NA NA NA NA 35132 XM_029342840.2 411 406 361 294 321 Q9NYI0 1.69e-93 PH and SEC7 domain-containing protein 3 (Epididymis tissue protein Li 20mP) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 D) (Exchange factor for ARF6 D) (Hepatocellular carcinoma-associated antigen 67) (Pleckstrin homology and SEC7 domain-containing protein 3) Homo sapiens (Human) regulation of ARF protein signal transduction [GO:0032012] GO:0005085; GO:0014069; GO:0032012; GO:0032587 35133 XR_006397175.1 27 8 5 10 27 NA NA NA NA NA NA 35134 XM_044319176.1 137 113 192 125 413 Q9HCU4 3.83e-70 Cadherin EGF LAG seven-pass G-type receptor 2 (Cadherin family member 10) (Epidermal growth factor-like protein 2) (EGF-like protein 2) (Flamingo homolog 3) (Multiple epidermal growth factor-like domains protein 3) (Multiple EGF-like domains protein 3) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebrospinal fluid secretion [GO:0033326]; cilium assembly [GO:0060271]; cilium movement [GO:0003341]; dendrite morphogenesis [GO:0048813]; G protein-coupled receptor signaling pathway [GO:0007186]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; neural plate anterior/posterior regionalization [GO:0021999]; regulation of cell-cell adhesion [GO:0022407]; regulation of DNA-templated transcription [GO:0006355]; regulation of protein localization [GO:0032880]; ventricular system development [GO:0021591]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0003341; GO:0004930; GO:0005509; GO:0005737; GO:0005886; GO:0006355; GO:0007156; GO:0007186; GO:0016020; GO:0016055; GO:0021591; GO:0021999; GO:0022407; GO:0032880; GO:0033326; GO:0048813; GO:0060071; GO:0060271; GO:0097475; GO:0098609 35135 XM_044319176.1 137 113 192 125 413 Q9HCU4 2.25e-56 Cadherin EGF LAG seven-pass G-type receptor 2 (Cadherin family member 10) (Epidermal growth factor-like protein 2) (EGF-like protein 2) (Flamingo homolog 3) (Multiple epidermal growth factor-like domains protein 3) (Multiple EGF-like domains protein 3) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebrospinal fluid secretion [GO:0033326]; cilium assembly [GO:0060271]; cilium movement [GO:0003341]; dendrite morphogenesis [GO:0048813]; G protein-coupled receptor signaling pathway [GO:0007186]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; neural plate anterior/posterior regionalization [GO:0021999]; regulation of cell-cell adhesion [GO:0022407]; regulation of DNA-templated transcription [GO:0006355]; regulation of protein localization [GO:0032880]; ventricular system development [GO:0021591]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0003341; GO:0004930; GO:0005509; GO:0005737; GO:0005886; GO:0006355; GO:0007156; GO:0007186; GO:0016020; GO:0016055; GO:0021591; GO:0021999; GO:0022407; GO:0032880; GO:0033326; GO:0048813; GO:0060071; GO:0060271; GO:0097475; GO:0098609 35136 XM_044319176.1 137 113 192 125 413 Q9HCU4 5.34e-53 Cadherin EGF LAG seven-pass G-type receptor 2 (Cadherin family member 10) (Epidermal growth factor-like protein 2) (EGF-like protein 2) (Flamingo homolog 3) (Multiple epidermal growth factor-like domains protein 3) (Multiple EGF-like domains protein 3) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebrospinal fluid secretion [GO:0033326]; cilium assembly [GO:0060271]; cilium movement [GO:0003341]; dendrite morphogenesis [GO:0048813]; G protein-coupled receptor signaling pathway [GO:0007186]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; neural plate anterior/posterior regionalization [GO:0021999]; regulation of cell-cell adhesion [GO:0022407]; regulation of DNA-templated transcription [GO:0006355]; regulation of protein localization [GO:0032880]; ventricular system development [GO:0021591]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0003341; GO:0004930; GO:0005509; GO:0005737; GO:0005886; GO:0006355; GO:0007156; GO:0007186; GO:0016020; GO:0016055; GO:0021591; GO:0021999; GO:0022407; GO:0032880; GO:0033326; GO:0048813; GO:0060071; GO:0060271; GO:0097475; GO:0098609 35137 XM_044319176.1 137 113 192 125 413 Q9HCU4 1.72e-51 Cadherin EGF LAG seven-pass G-type receptor 2 (Cadherin family member 10) (Epidermal growth factor-like protein 2) (EGF-like protein 2) (Flamingo homolog 3) (Multiple epidermal growth factor-like domains protein 3) (Multiple EGF-like domains protein 3) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebrospinal fluid secretion [GO:0033326]; cilium assembly [GO:0060271]; cilium movement [GO:0003341]; dendrite morphogenesis [GO:0048813]; G protein-coupled receptor signaling pathway [GO:0007186]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; neural plate anterior/posterior regionalization [GO:0021999]; regulation of cell-cell adhesion [GO:0022407]; regulation of DNA-templated transcription [GO:0006355]; regulation of protein localization [GO:0032880]; ventricular system development [GO:0021591]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0003341; GO:0004930; GO:0005509; GO:0005737; GO:0005886; GO:0006355; GO:0007156; GO:0007186; GO:0016020; GO:0016055; GO:0021591; GO:0021999; GO:0022407; GO:0032880; GO:0033326; GO:0048813; GO:0060071; GO:0060271; GO:0097475; GO:0098609 35138 XR_003826490.2 22 5 18 17 64 NA NA NA NA NA NA 35139 XM_044325785.1 328 329 396 573 749 Q9H251 0 Cadherin-23 (Otocadherin) Homo sapiens (Human) auditory receptor cell stereocilium organization [GO:0060088]; calcium ion transport [GO:0006816]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; equilibrioception [GO:0050957]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; locomotory behavior [GO:0007626]; photoreceptor cell maintenance [GO:0045494]; post-embryonic animal organ morphogenesis [GO:0048563]; regulation of cytosolic calcium ion concentration [GO:0051480]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] GO:0001917; GO:0005509; GO:0005813; GO:0006816; GO:0007156; GO:0007601; GO:0007605; GO:0007626; GO:0016020; GO:0016339; GO:0016342; GO:0032420; GO:0032426; GO:0045296; GO:0045494; GO:0048563; GO:0050896; GO:0050953; GO:0050957; GO:0051480; GO:0060088; GO:0060091; GO:0098683; GO:0098684; GO:0098742 35140 XM_044325785.1 328 329 396 573 749 Q9H251 0 Cadherin-23 (Otocadherin) Homo sapiens (Human) auditory receptor cell stereocilium organization [GO:0060088]; calcium ion transport [GO:0006816]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; equilibrioception [GO:0050957]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; locomotory behavior [GO:0007626]; photoreceptor cell maintenance [GO:0045494]; post-embryonic animal organ morphogenesis [GO:0048563]; regulation of cytosolic calcium ion concentration [GO:0051480]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] GO:0001917; GO:0005509; GO:0005813; GO:0006816; GO:0007156; GO:0007601; GO:0007605; GO:0007626; GO:0016020; GO:0016339; GO:0016342; GO:0032420; GO:0032426; GO:0045296; GO:0045494; GO:0048563; GO:0050896; GO:0050953; GO:0050957; GO:0051480; GO:0060088; GO:0060091; GO:0098683; GO:0098684; GO:0098742 35141 XM_044325785.1 328 329 396 573 749 Q9H251 0 Cadherin-23 (Otocadherin) Homo sapiens (Human) auditory receptor cell stereocilium organization [GO:0060088]; calcium ion transport [GO:0006816]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; equilibrioception [GO:0050957]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; locomotory behavior [GO:0007626]; photoreceptor cell maintenance [GO:0045494]; post-embryonic animal organ morphogenesis [GO:0048563]; regulation of cytosolic calcium ion concentration [GO:0051480]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] GO:0001917; GO:0005509; GO:0005813; GO:0006816; GO:0007156; GO:0007601; GO:0007605; GO:0007626; GO:0016020; GO:0016339; GO:0016342; GO:0032420; GO:0032426; GO:0045296; GO:0045494; GO:0048563; GO:0050896; GO:0050953; GO:0050957; GO:0051480; GO:0060088; GO:0060091; GO:0098683; GO:0098684; GO:0098742 35142 XM_044325785.1 328 329 396 573 749 Q9H251 0 Cadherin-23 (Otocadherin) Homo sapiens (Human) auditory receptor cell stereocilium organization [GO:0060088]; calcium ion transport [GO:0006816]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; equilibrioception [GO:0050957]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; locomotory behavior [GO:0007626]; photoreceptor cell maintenance [GO:0045494]; post-embryonic animal organ morphogenesis [GO:0048563]; regulation of cytosolic calcium ion concentration [GO:0051480]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] GO:0001917; GO:0005509; GO:0005813; GO:0006816; GO:0007156; GO:0007601; GO:0007605; GO:0007626; GO:0016020; GO:0016339; GO:0016342; GO:0032420; GO:0032426; GO:0045296; GO:0045494; GO:0048563; GO:0050896; GO:0050953; GO:0050957; GO:0051480; GO:0060088; GO:0060091; GO:0098683; GO:0098684; GO:0098742 35143 XM_044325785.1 328 329 396 573 749 Q9H251 0 Cadherin-23 (Otocadherin) Homo sapiens (Human) auditory receptor cell stereocilium organization [GO:0060088]; calcium ion transport [GO:0006816]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; equilibrioception [GO:0050957]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; locomotory behavior [GO:0007626]; photoreceptor cell maintenance [GO:0045494]; post-embryonic animal organ morphogenesis [GO:0048563]; regulation of cytosolic calcium ion concentration [GO:0051480]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] GO:0001917; GO:0005509; GO:0005813; GO:0006816; GO:0007156; GO:0007601; GO:0007605; GO:0007626; GO:0016020; GO:0016339; GO:0016342; GO:0032420; GO:0032426; GO:0045296; GO:0045494; GO:0048563; GO:0050896; GO:0050953; GO:0050957; GO:0051480; GO:0060088; GO:0060091; GO:0098683; GO:0098684; GO:0098742 35144 XM_044325785.1 328 329 396 573 749 Q9H251 2.53e-177 Cadherin-23 (Otocadherin) Homo sapiens (Human) auditory receptor cell stereocilium organization [GO:0060088]; calcium ion transport [GO:0006816]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; equilibrioception [GO:0050957]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; locomotory behavior [GO:0007626]; photoreceptor cell maintenance [GO:0045494]; post-embryonic animal organ morphogenesis [GO:0048563]; regulation of cytosolic calcium ion concentration [GO:0051480]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] GO:0001917; GO:0005509; GO:0005813; GO:0006816; GO:0007156; GO:0007601; GO:0007605; GO:0007626; GO:0016020; GO:0016339; GO:0016342; GO:0032420; GO:0032426; GO:0045296; GO:0045494; GO:0048563; GO:0050896; GO:0050953; GO:0050957; GO:0051480; GO:0060088; GO:0060091; GO:0098683; GO:0098684; GO:0098742 35145 XM_044325785.1 328 329 396 573 749 Q9H251 7.4e-53 Cadherin-23 (Otocadherin) Homo sapiens (Human) auditory receptor cell stereocilium organization [GO:0060088]; calcium ion transport [GO:0006816]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; equilibrioception [GO:0050957]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; locomotory behavior [GO:0007626]; photoreceptor cell maintenance [GO:0045494]; post-embryonic animal organ morphogenesis [GO:0048563]; regulation of cytosolic calcium ion concentration [GO:0051480]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] GO:0001917; GO:0005509; GO:0005813; GO:0006816; GO:0007156; GO:0007601; GO:0007605; GO:0007626; GO:0016020; GO:0016339; GO:0016342; GO:0032420; GO:0032426; GO:0045296; GO:0045494; GO:0048563; GO:0050896; GO:0050953; GO:0050957; GO:0051480; GO:0060088; GO:0060091; GO:0098683; GO:0098684; GO:0098742 35146 XM_029343148.2 853 237 670 59 581 Q2KJI2 0 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (Oligosaccharyl transferase subunit STT3A) (STT3-A) (EC 2.4.99.18) Bos taurus (Bovine) co-translational protein modification [GO:0043686]; post-translational protein modification [GO:0043687]; protein N-linked glycosylation via asparagine [GO:0018279] GO:0004579; GO:0018279; GO:0035000; GO:0043686; GO:0043687; GO:0046872 35147 XM_044328216.1 95 77 64 70 130 E1BYJ2 0 DNA mismatch repair protein Msh6 Gallus gallus (Chicken) mismatch repair [GO:0006298]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; negative regulation of DNA endoreduplication [GO:0032876]; positive regulation of B cell proliferation [GO:0030890] GO:0003690; GO:0005524; GO:0005634; GO:0006298; GO:0007095; GO:0030890; GO:0030983; GO:0032301; GO:0032876; GO:0140664 35148 XM_029329864.2 0 32 0 2 0 P20072 4.36e-70 Annexin A7 (Annexin VII) (Annexin-7) (Synexin) Bos taurus (Bovine) NA GO:0005509; GO:0005544; GO:0005634; GO:0005737; GO:0042584 35149 XM_029328573.2 15 0 0 0 11 NA NA NA NA NA NA 35150 XM_029344153.2 7048 2850 1619 6972 7049 Q9DBP0 5.57e-159 Sodium-dependent phosphate transport protein 2B (Sodium-phosphate transport protein 2B) (Na(+)-dependent phosphate cotransporter 2B) (Sodium/phosphate cotransporter 2B) (Na(+)/Pi cotransporter 2B) (NaPi-2b) (Solute carrier family 34 member 2) Mus musculus (Mouse) cellular phosphate ion homeostasis [GO:0030643]; in utero embryonic development [GO:0001701]; phosphate ion transport [GO:0006817]; response to estrogen [GO:0043627]; sodium-dependent phosphate transport [GO:0044341] GO:0001701; GO:0005436; GO:0005903; GO:0006817; GO:0016020; GO:0016324; GO:0019904; GO:0030643; GO:0031402; GO:0031526; GO:0031528; GO:0031982; GO:0042301; GO:0043627; GO:0044341 35151 XM_029353453.2 12 13 19 36 75 P17124 8.35e-38 Histamine H2 receptor (H2R) (HH2R) (Gastric receptor I) Canis lupus familiaris (Dog) (Canis familiaris) chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; gastric acid secretion [GO:0001696]; positive regulation of vasoconstriction [GO:0045907] GO:0001696; GO:0004969; GO:0004993; GO:0005886; GO:0007187; GO:0007268; GO:0030425; GO:0030594; GO:0045202; GO:0045907 35152 XM_044325614.1 575 1518 854 1691 939 O43399 3.32e-22 Tumor protein D54 (hD54) (Tumor protein D52-like 2) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; regulation of cell population proliferation [GO:0042127] GO:0003723; GO:0005737; GO:0005975; GO:0042127; GO:0042803; GO:0048471 35153 XM_044320443.1 20 0 5 14 95 NA NA NA NA NA NA 35154 XM_029349939.2 4 0 2 17 0 NA NA NA NA NA NA 35155 XM_029350249.2 842 960 357 1021 686 NA NA NA NA NA NA 35156 XM_029329570.2 6 31 15 43 84 NA NA NA NA NA NA 35157 XR_003824113.2 277 128 119 100 362 NA NA NA NA NA NA 35158 XR_006393743.1 15 22 2 45 26 NA NA NA NA NA NA 35159 XM_029331490.2 14 13 1 21 12 NA NA NA NA NA NA 35160 XR_006391960.1 632 356 192 300 619 Q91VS8 2.34e-134 FERM, ARHGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR) (FERM, RhoGEF and pleckstrin domain-containing protein 2) Mus musculus (Mouse) actin cytoskeleton reorganization [GO:0031532]; cell adhesion [GO:0007155]; hair cycle process [GO:0022405]; neuron remodeling [GO:0016322]; osteoclast differentiation [GO:0030316]; podosome assembly [GO:0071800]; Rac protein signal transduction [GO:0016601]; regulation of integrin activation [GO:0033623]; semaphorin-plexin signaling pathway [GO:0071526] GO:0005085; GO:0005737; GO:0005829; GO:0005856; GO:0007155; GO:0008092; GO:0016322; GO:0016601; GO:0022405; GO:0030316; GO:0031532; GO:0033623; GO:0071526; GO:0071800 35161 XR_006391960.1 632 356 192 300 619 Q91VS8 2.34e-134 FERM, ARHGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR) (FERM, RhoGEF and pleckstrin domain-containing protein 2) Mus musculus (Mouse) actin cytoskeleton reorganization [GO:0031532]; cell adhesion [GO:0007155]; hair cycle process [GO:0022405]; neuron remodeling [GO:0016322]; osteoclast differentiation [GO:0030316]; podosome assembly [GO:0071800]; Rac protein signal transduction [GO:0016601]; regulation of integrin activation [GO:0033623]; semaphorin-plexin signaling pathway [GO:0071526] GO:0005085; GO:0005737; GO:0005829; GO:0005856; GO:0007155; GO:0008092; GO:0016322; GO:0016601; GO:0022405; GO:0030316; GO:0031532; GO:0033623; GO:0071526; GO:0071800 35162 XM_029338162.2 949 951 556 1100 1618 Q5SUC9 6.12e-74 Protein SCO1 homolog, mitochondrial Mus musculus (Mouse) cellular copper ion homeostasis [GO:0006878]; cyclooxygenase pathway [GO:0019371]; mitochondrial cytochrome c oxidase assembly [GO:0033617]; negative regulation of cellular response to insulin stimulus [GO:1900077]; negative regulation of proteasomal protein catabolic process [GO:1901799]; negative regulation of protein kinase B signaling [GO:0051898]; post-transcriptional regulation of gene expression [GO:0010608]; proteasomal protein catabolic process [GO:0010498]; protein localization to plasma membrane [GO:0072659]; regulation of cytochrome-c oxidase activity [GO:1904959] GO:0005739; GO:0005743; GO:0006878; GO:0010498; GO:0010608; GO:0019371; GO:0030016; GO:0033617; GO:0046872; GO:0051898; GO:0072659; GO:1900077; GO:1901799; GO:1904959 35163 XR_006397892.1 102 82 54 31 52 NA NA NA NA NA NA 35164 XM_029332687.2 28 0 23 5 21 NA NA NA NA NA NA 35165 XM_029340908.2 0 159 260 555 955 C5H5C4 2.33e-80 Palmitoleoyl-protein carboxylesterase notum1a (EC 3.1.1.98) Danio rerio (Zebrafish) (Brachydanio rerio) anterior/posterior pattern specification [GO:0009952]; GPI anchor release [GO:0006507]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of Wnt signaling pathway [GO:0030178]; neural tube patterning [GO:0021532]; protein depalmitoleylation [GO:1990697]; Wnt signaling pathway [GO:0016055] GO:0005576; GO:0006507; GO:0009952; GO:0016055; GO:0021532; GO:0030178; GO:0090090; GO:1990697; GO:1990699 35166 XM_044328869.1 24 17 25 30 31 Q96AY4 2.22e-105 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35167 XM_044328869.1 24 17 25 30 31 Q96AY4 1.34e-100 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35168 XM_044328869.1 24 17 25 30 31 Q96AY4 1.75e-100 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35169 XM_044328869.1 24 17 25 30 31 Q96AY4 5.1e-73 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35170 XM_029337669.2 140 187 40 567 127 P32674 1.26e-36 Probable dehydratase PflD (EC 4.2.1.-) Escherichia coli (strain K12) NA GO:0005829; GO:0016829 35171 XM_044308354.1 1686 732 871 136 318 Q9JHA8 4.1e-66 von Willebrand factor A domain-containing protein 7 (Protein G7c) Mus musculus (Mouse) NA GO:0005576 35172 XM_044317531.1 0 3 16 9 3 NA NA NA NA NA NA 35173 XM_044323187.1 1106 722 385 773 667 NA NA NA NA NA NA 35174 XM_029324369.2 3 19 28 76 28 Q80XJ3 4.3e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 35175 XR_006392082.1 74 45 46 33 66 NA NA NA NA NA NA 35176 XM_029323519.2 28 39 65 69 52 NA NA NA NA NA NA 35177 XM_029323667.2 317 134 104 211 197 Q9C0B7 8.59e-134 Transport and Golgi organization protein 6 homolog (Transmembrane and coiled-coil domain-containing protein 7) Homo sapiens (Human) protein secretion [GO:0009306] GO:0009306; GO:0016020 35178 XM_029334444.2 27 1 2 13 5 NA NA NA NA NA NA 35179 XM_044309660.1 0 0 12 0 0 NA NA NA NA NA NA 35180 XM_044325508.1 7 77 29 197 51 NA NA NA NA NA NA 35181 XM_029329079.2 16 0 111 54 0 P41778 2.74e-159 Pre-B-cell leukemia transcription factor 1 (Homeobox protein PBX1) Mus musculus (Mouse) adrenal gland development [GO:0030325]; animal organ morphogenesis [GO:0009887]; anterior/posterior pattern specification [GO:0009952]; brain development [GO:0007420]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell population proliferation [GO:0008283]; embryonic hemopoiesis [GO:0035162]; embryonic limb morphogenesis [GO:0030326]; embryonic organ development [GO:0048568]; embryonic skeletal system development [GO:0048706]; eye development [GO:0001654]; G2/M transition of mitotic cell cycle [GO:0000086]; natural killer cell differentiation [GO:0001779]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of neuron differentiation [GO:0045665]; neuron development [GO:0048666]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proximal/distal pattern formation [GO:0009954]; regulation of cell population proliferation [GO:0042127]; regulation of ossification [GO:0030278]; regulation of transcription by RNA polymerase II [GO:0006357]; sex differentiation [GO:0007548]; spleen development [GO:0048536]; stem cell proliferation [GO:0072089]; steroid biosynthetic process [GO:0006694]; thymus development [GO:0048538]; urogenital system development [GO:0001655] GO:0000086; GO:0000976; GO:0000977; GO:0000978; GO:0000981; GO:0001221; GO:0001222; GO:0001228; GO:0001654; GO:0001655; GO:0001658; GO:0001779; GO:0003677; GO:0005634; GO:0005654; GO:0005667; GO:0005737; GO:0006357; GO:0006694; GO:0007420; GO:0007548; GO:0008283; GO:0009887; GO:0009952; GO:0009954; GO:0010971; GO:0030278; GO:0030325; GO:0030326; GO:0035162; GO:0042127; GO:0043433; GO:0043565; GO:0045665; GO:0045944; GO:0048536; GO:0048538; GO:0048568; GO:0048666; GO:0048706; GO:0072089; GO:0090575; GO:0140297; GO:1990837; GO:2000648 35182 XM_029357839.2 367 82 143 102 155 Q5XXP2 4.51e-28 Melanopsin (Opsin-4) Phodopus sungorus (Striped hairy-footed hamster) (Djungarian hamster) hyaloid vascular plexus regression [GO:1990384]; optokinetic behavior [GO:0007634]; phototransduction [GO:0007602]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511]; visual perception [GO:0007601] GO:0005502; GO:0005886; GO:0007601; GO:0007602; GO:0007634; GO:0008020; GO:0016020; GO:0030424; GO:0030425; GO:0042752; GO:0043204; GO:0048511; GO:1990384 35183 XM_044315448.1 182 115 16 111 34 Q7RTR2 4.2e-23 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 35184 XR_006392344.1 26 69 51 19 20 Q5R9I3 9.41e-45 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cellular response to glucose starvation [GO:0042149]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; protein phosphorylation [GO:0006468] GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005930; GO:0006468; GO:0016236; GO:0035032; GO:0042149; GO:0045324; GO:0106310 35185 XM_029342627.2 157 18 88 171 433 NA NA NA NA NA NA 35186 XM_044318622.1 454 357 355 450 652 Q6NRG5 0 NADPH-dependent diflavin oxidoreductase 1 (EC 1.18.1.-) (NADPH-dependent FMN and FAD-containing oxidoreductase) Xenopus laevis (African clawed frog) cell death [GO:0008219]; cellular response to menadione [GO:0036245]; iron-sulfur cluster assembly [GO:0016226] GO:0003958; GO:0005829; GO:0008219; GO:0009055; GO:0010181; GO:0016226; GO:0016653; GO:0016731; GO:0036245; GO:0048471; GO:0050660; GO:0050661 35187 XM_029350470.2 587 505 613 1206 1156 NA NA NA NA NA NA 35188 XM_029330301.2 2858 3796 3674 1825 1272 Q9H0K1 2.37e-156 Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2) Homo sapiens (Human) cellular response to glucose starvation [GO:0042149]; intracellular signal transduction [GO:0035556]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of insulin receptor signaling pathway [GO:0046626] GO:0000287; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005789; GO:0006468; GO:0035556; GO:0042149; GO:0046626; GO:0046777; GO:0106310 35189 XR_003822741.2 107 52 57 151 153 NA NA NA NA NA NA 35190 XM_044312744.1 54 70 73 107 141 NA NA NA NA NA NA 35191 XM_029353719.2 1241 1091 1024 1273 1431 NA NA NA NA NA NA 35192 XM_029348525.2 38 25 0 8 15 NA NA NA NA NA NA 35193 XR_003824232.2 23 3 17 26 48 NA NA NA NA NA NA 35194 XM_044328555.1 3250 2242 1517 3472 2465 Q6NTN5 0 Myotubularin-related protein 13 (Inactive phosphatidylinositol 3-phosphatase 13) (SET-binding factor 2) Xenopus laevis (African clawed frog) autophagy [GO:0006914] GO:0005085; GO:0005737; GO:0006914; GO:0016020 35195 XM_029333694.2 805 585 360 558 689 Q05752 3.7e-21 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (Complex I-B14.5a) (CI-B14.5a) (NADH-ubiquinone oxidoreductase subunit B14.5a) Bos taurus (Bovine) ATP synthesis coupled electron transport [GO:0042773]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrial translation [GO:0032543] GO:0003735; GO:0005739; GO:0005743; GO:0005747; GO:0005761; GO:0006120; GO:0016491; GO:0032543; GO:0042773 35196 XM_029334294.2 99 114 91 352 144 NA NA NA NA NA NA 35197 XR_006391555.1 0 15 0 0 76 NA NA NA NA NA NA 35198 XM_029335933.2 719 855 533 506 350 Q9CQY1 2.91e-30 Ubiquitin-like protein ATG12 (Autophagy-related protein 12) (APG12-like) Mus musculus (Mouse) autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; autophagy of nucleus [GO:0044804]; C-terminal protein lipidation [GO:0006501]; macroautophagy [GO:0016236]; negative regulation of defense response to virus [GO:0050687]; negative regulation of innate immune response [GO:0045824]; negative regulation of type I interferon production [GO:0032480]; positive regulation of viral translation [GO:1904973]; protein lipidation [GO:0006497]; regulation of autophagosome maturation [GO:1901096] GO:0000045; GO:0000422; GO:0005654; GO:0005776; GO:0005829; GO:0006497; GO:0006501; GO:0006914; GO:0016020; GO:0016236; GO:0032480; GO:0032991; GO:0034045; GO:0034274; GO:0043231; GO:0044804; GO:0045824; GO:0050687; GO:1901096; GO:1904973; GO:1990234 35199 XM_044310954.1 0 0 9 4 0 Q9W6S5 2.97e-88 Allantoicase (EC 3.5.3.4) (Allantoate amidinohydrolase) Xenopus laevis (African clawed frog) allantoin catabolic process [GO:0000256]; purine nucleobase metabolic process [GO:0006144] GO:0000256; GO:0004037; GO:0006144 35200 XM_044316024.1 74 24 29 69 234 NA NA NA NA NA NA 35201 XM_044328482.1 60 48 11 61 76 Q91611 7.71e-31 Desert hedgehog protein B (EC 3.1.-.-) (Desert hedgehog protein 2) (DHH-2) (Hedgehog protein 4) (X-HH4) [Cleaved into: Desert hedgehog protein B N-product] Xenopus laevis (African clawed frog) cell-cell signaling [GO:0007267]; positive regulation of smoothened signaling pathway [GO:0045880]; protein autoprocessing [GO:0016540]; self proteolysis [GO:0097264] GO:0000139; GO:0005113; GO:0005576; GO:0005789; GO:0005886; GO:0007267; GO:0008233; GO:0016540; GO:0045880; GO:0046872; GO:0097264; GO:0140853 35202 XM_029332985.2 132 46 84 148 102 NA NA NA NA NA NA 35203 XR_003824285.2 0 0 0 0 18 NA NA NA NA NA NA 35204 XM_044326708.1 60 34 24 29 76 NA NA NA NA NA NA 35205 XM_029354556.2 61 85 52 54 50 O00534 8.79e-134 von Willebrand factor A domain-containing protein 5A (Breast cancer suppressor candidate 1) (BCSC-1) (Loss of heterozygosity 11 chromosomal region 2 gene A protein) Homo sapiens (Human) NA GO:0005654 35206 XM_029343287.2 127 0 280 237 223 NA NA NA NA NA NA 35207 XM_029338478.2 403 291 488 503 619 Q5ZLG0 0 Acetoacetyl-CoA synthetase (EC 6.2.1.16) Gallus gallus (Chicken) fatty acid metabolic process [GO:0006631]; positive regulation of insulin secretion [GO:0032024] GO:0005524; GO:0005829; GO:0006631; GO:0030729; GO:0032024 35208 XM_029336570.2 203 0 49 16 0 P63079 2.9e-73 Gamma-aminobutyric acid receptor subunit beta-3 (GABA(A) receptor subunit beta-3) Rattus norvegicus (Rat) brain development [GO:0007420]; cellular response to histamine [GO:0071420]; cellular response to zinc ion [GO:0071294]; cerebellum development [GO:0021549]; chemical synaptic transmission [GO:0007268]; chemical synaptic transmission, postsynaptic [GO:0099565]; chloride transmembrane transport [GO:1902476]; circadian sleep/wake cycle, REM sleep [GO:0042747]; cochlea development [GO:0090102]; exploration behavior [GO:0035640]; gamma-aminobutyric acid signaling pathway [GO:0007214]; hard palate development [GO:0060022]; inhibitory postsynaptic potential [GO:0060080]; inhibitory synapse assembly [GO:1904862]; inner ear receptor cell development [GO:0060119]; innervation [GO:0060384]; ion transmembrane transport [GO:0034220]; learning [GO:0007612]; memory [GO:0007613]; motor behavior [GO:0061744]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; nervous system development [GO:0007399]; nervous system process [GO:0050877]; neuron development [GO:0048666]; regulation of membrane potential [GO:0042391]; regulation of neuron apoptotic process [GO:0043523]; regulation of postsynaptic membrane potential [GO:0060078]; reproductive behavior [GO:0019098]; response to anesthetic [GO:0072347]; response to xenobiotic stimulus [GO:0009410]; roof of mouth development [GO:0060021]; sensory perception of sound [GO:0007605]; signal transduction [GO:0007165]; social behavior [GO:0035176]; synaptic transmission, GABAergic [GO:0051932] GO:0004890; GO:0005216; GO:0005231; GO:0005254; GO:0005886; GO:0007165; GO:0007214; GO:0007268; GO:0007399; GO:0007420; GO:0007605; GO:0007612; GO:0007613; GO:0009410; GO:0009986; GO:0019098; GO:0021549; GO:0022851; GO:0030594; GO:0030659; GO:0034220; GO:0034707; GO:0035176; GO:0035612; GO:0035640; GO:0042391; GO:0042747; GO:0042802; GO:0043005; GO:0043195; GO:0043523; GO:0043524; GO:0045202; GO:0045211; GO:0048666; GO:0050877; GO:0051932; GO:0060021; GO:0060022; GO:0060077; GO:0060078; GO:0060080; GO:0060119; GO:0060384; GO:0061744; GO:0071294; GO:0071420; GO:0072347; GO:0090102; GO:0098982; GO:0099565; GO:0099634; GO:1901215; GO:1902476; GO:1902711; GO:1904315; GO:1904862 35209 XM_044326327.1 53 13 29 67 10 NA NA NA NA NA NA 35210 XM_044309708.1 63 59 114 144 232 NA NA NA NA NA NA 35211 XM_044319315.1 1008 679 425 461 566 P19387 5.14e-152 DNA-directed RNA polymerase II subunit RPB3 (RNA polymerase II subunit 3) (RNA polymerase II subunit B3) (DNA-directed RNA polymerase II 33 kDa polypeptide) (RPB33) (DNA-directed RNA polymerase II subunit C) (RPB31) Homo sapiens (Human) transcription by RNA polymerase II [GO:0006366] GO:0003677; GO:0003899; GO:0005634; GO:0005654; GO:0005665; GO:0005829; GO:0006366; GO:0046983 35212 XM_044315107.1 7 13 0 1 0 NA NA NA NA NA NA 35213 XM_029332856.2 30 0 12 2 0 NA NA NA NA NA NA 35214 XM_029357751.2 173 0 0 139 275 P52483 1.92e-95 Ubiquitin-conjugating enzyme E2 E3 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme E3) (UbcM2) (Ubiquitin carrier protein E3) (Ubiquitin-conjugating enzyme E2-23 kDa) (Ubiquitin-protein ligase E3) Mus musculus (Mouse) protein K11-linked ubiquitination [GO:0070979]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209] GO:0000209; GO:0004842; GO:0005524; GO:0005634; GO:0005737; GO:0061631; GO:0070534; GO:0070936; GO:0070979 35215 XM_029339270.2 39 9 4 44 130 Q9N2B7 7.12e-39 5-hydroxytryptamine receptor 1B (5-HT-1B) (5-HT1B) (Serotonin receptor 1B) Gorilla gorilla gorilla (Western lowland gorilla) adenylate cyclase-inhibiting serotonin receptor signaling pathway [GO:0007198]; behavior [GO:0007610]; bone remodeling [GO:0046849]; cellular response to alkaloid [GO:0071312]; cellular response to xenobiotic stimulus [GO:0071466]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; negative regulation of serotonin secretion [GO:0014063]; regulation of behavior [GO:0050795]; vasoconstriction [GO:0042310] GO:0004993; GO:0005886; GO:0007187; GO:0007198; GO:0007268; GO:0007610; GO:0014063; GO:0030425; GO:0030594; GO:0042310; GO:0045202; GO:0046849; GO:0050795; GO:0051378; GO:0071312; GO:0071466 35216 XR_006392464.1 15 6 58 70 4 Q8VD65 9.12e-70 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) Mus musculus (Mouse) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016236; GO:0016241; GO:0030242; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 35217 XR_006392464.1 15 6 58 70 4 Q8VD65 9.12e-70 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) Mus musculus (Mouse) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016236; GO:0016241; GO:0030242; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 35218 XR_006392464.1 15 6 58 70 4 Q8VD65 9.12e-70 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) Mus musculus (Mouse) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016236; GO:0016241; GO:0030242; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 35219 XM_044325138.1 3 74 0 292 0 NA NA NA NA NA NA 35220 XM_029349412.2 3 15 0 3 0 NA NA NA NA NA NA 35221 XM_044324781.1 0 136 126 59 597 NA NA NA NA NA NA 35222 XM_044309694.1 0 9 0 0 0 NA NA NA NA NA NA 35223 XR_003828318.2 37 12 27 153 91 NA NA NA NA NA NA 35224 XM_029349715.2 286 98 48 104 40 Q8UUZ1 2.74e-124 Protein mab-21-like 2 Danio rerio (Zebrafish) (Brachydanio rerio) camera-type eye development [GO:0043010]; closure of optic fissure [GO:0061386]; cornea development in camera-type eye [GO:0061303]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic eye morphogenesis [GO:0048048]; enteric nervous system development [GO:0048484]; eye development [GO:0001654]; lens development in camera-type eye [GO:0002088]; lens morphogenesis in camera-type eye [GO:0002089]; retina development in camera-type eye [GO:0060041] GO:0001654; GO:0002088; GO:0002089; GO:0005634; GO:0005737; GO:0043010; GO:0048048; GO:0048484; GO:0048701; GO:0060041; GO:0061303; GO:0061386 35225 XM_044326498.1 15 2 11 1 55 NA NA NA NA NA NA 35226 XM_029346314.2 1203 690 1058 1433 2070 NA NA NA NA NA NA 35227 XM_029347398.2 404 385 223 486 423 Q8BID8 1.01e-174 F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14) Mus musculus (Mouse) SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004842; GO:0005737; GO:0006511; GO:0019005; GO:0031146 35228 XR_006391343.1 18 1 9 16 0 NA NA NA NA NA NA 35229 XM_044322973.1 147 95 130 174 157 NA NA NA NA NA NA 35230 XM_029339932.2 33315 31776 20050 35951 41690 G8HTB6 0 ZP domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 35231 XM_029324028.2 11 113 29 37 62 NA NA NA NA NA NA 35232 XM_029344438.2 207 286 0 129 228 A0A1D5PUP4 0 Reversion-inducing cysteine-rich protein with Kazal motifs Gallus gallus (Chicken) blood vessel maturation [GO:0001955]; extracellular matrix organization [GO:0030198]; negative regulation of metalloendopeptidase activity [GO:1904684]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; regulation of angiogenesis [GO:0045765]; regulation of establishment of blood-brain barrier [GO:0090210]; sprouting angiogenesis [GO:0002040] GO:0001955; GO:0002040; GO:0004866; GO:0004867; GO:0005615; GO:0005886; GO:0008191; GO:0030198; GO:0045765; GO:0090210; GO:0090263; GO:1904684; GO:1904928; GO:1990909 35233 XM_029337687.2 48 12 20 87 241 NA NA NA NA NA NA 35234 XM_029331708.2 279 57 316 489 776 Q9H0J9 2.5e-53 Protein mono-ADP-ribosyltransferase PARP12 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 12) (ARTD12) (Poly [ADP-ribose] polymerase 12) (PARP-12) (Zinc finger CCCH domain-containing protein 1) Homo sapiens (Human) protein auto-ADP-ribosylation [GO:0070213] GO:0003723; GO:0003950; GO:0005634; GO:0016779; GO:0046872; GO:0070213; GO:0140803; GO:1990404 35235 XR_006394953.1 71 84 46 50 73 F1RB95 1.01e-48 NA NA NA NA 35236 XM_044328788.1 549 370 442 527 478 F8VPZ5 3.5e-76 DNA excision repair protein ERCC-6 (EC 3.6.4.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB) Mus musculus (Mouse) base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; chromatin remodeling [GO:0006338]; DNA damage checkpoint signaling [GO:0000077]; DNA protection [GO:0042262]; DNA repair [GO:0006281]; double-strand break repair via classical nonhomologous end joining [GO:0097680]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; multicellular organism growth [GO:0035264]; negative regulation of double-strand break repair via nonhomologous end joining [GO:2001033]; neurogenesis [GO:0022008]; neuron differentiation [GO:0030182]; neuron projection development [GO:0031175]; photoreceptor cell maintenance [GO:0045494]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of gene expression [GO:0010628]; positive regulation of histone acetylation [GO:0035066]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription by RNA polymerase III [GO:0045945]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; pyrimidine dimer repair [GO:0006290]; regulation of DNA-templated transcription elongation [GO:0032784]; regulation of transcription elongation by RNA polymerase II [GO:0034243]; response to gamma radiation [GO:0010332]; response to oxidative stress [GO:0006979]; response to superoxide [GO:0000303]; response to toxic substance [GO:0009636]; response to UV [GO:0009411]; response to UV-B [GO:0010224]; response to X-ray [GO:0010165]; single strand break repair [GO:0000012]; transcription elongation by RNA polymerase I [GO:0006362]; transcription-coupled nucleotide-excision repair [GO:0006283] GO:0000012; GO:0000077; GO:0000303; GO:0002230; GO:0003677; GO:0003682; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0006281; GO:0006283; GO:0006284; GO:0006290; GO:0006338; GO:0006362; GO:0006974; GO:0006979; GO:0007254; GO:0008022; GO:0008023; GO:0008094; GO:0008630; GO:0009411; GO:0009636; GO:0010165; GO:0010224; GO:0010332; GO:0010628; GO:0016604; GO:0016887; GO:0022008; GO:0030182; GO:0030296; GO:0031175; GO:0032784; GO:0032786; GO:0033141; GO:0034243; GO:0035066; GO:0035264; GO:0042262; GO:0043565; GO:0044877; GO:0045494; GO:0045739; GO:0045943; GO:0045944; GO:0045945; GO:0047485; GO:0060261; GO:0070063; GO:0090734; GO:0097680; GO:0110016; GO:0140658; GO:1905168; GO:2001033 35237 XM_044328788.1 549 370 442 527 478 F8VPZ5 3.32e-49 DNA excision repair protein ERCC-6 (EC 3.6.4.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB) Mus musculus (Mouse) base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; chromatin remodeling [GO:0006338]; DNA damage checkpoint signaling [GO:0000077]; DNA protection [GO:0042262]; DNA repair [GO:0006281]; double-strand break repair via classical nonhomologous end joining [GO:0097680]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; multicellular organism growth [GO:0035264]; negative regulation of double-strand break repair via nonhomologous end joining [GO:2001033]; neurogenesis [GO:0022008]; neuron differentiation [GO:0030182]; neuron projection development [GO:0031175]; photoreceptor cell maintenance [GO:0045494]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of gene expression [GO:0010628]; positive regulation of histone acetylation [GO:0035066]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription by RNA polymerase III [GO:0045945]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; pyrimidine dimer repair [GO:0006290]; regulation of DNA-templated transcription elongation [GO:0032784]; regulation of transcription elongation by RNA polymerase II [GO:0034243]; response to gamma radiation [GO:0010332]; response to oxidative stress [GO:0006979]; response to superoxide [GO:0000303]; response to toxic substance [GO:0009636]; response to UV [GO:0009411]; response to UV-B [GO:0010224]; response to X-ray [GO:0010165]; single strand break repair [GO:0000012]; transcription elongation by RNA polymerase I [GO:0006362]; transcription-coupled nucleotide-excision repair [GO:0006283] GO:0000012; GO:0000077; GO:0000303; GO:0002230; GO:0003677; GO:0003682; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0006281; GO:0006283; GO:0006284; GO:0006290; GO:0006338; GO:0006362; GO:0006974; GO:0006979; GO:0007254; GO:0008022; GO:0008023; GO:0008094; GO:0008630; GO:0009411; GO:0009636; GO:0010165; GO:0010224; GO:0010332; GO:0010628; GO:0016604; GO:0016887; GO:0022008; GO:0030182; GO:0030296; GO:0031175; GO:0032784; GO:0032786; GO:0033141; GO:0034243; GO:0035066; GO:0035264; GO:0042262; GO:0043565; GO:0044877; GO:0045494; GO:0045739; GO:0045943; GO:0045944; GO:0045945; GO:0047485; GO:0060261; GO:0070063; GO:0090734; GO:0097680; GO:0110016; GO:0140658; GO:1905168; GO:2001033 35238 XR_003823843.2 54 47 14 38 80 NA NA NA NA NA NA 35239 XM_029349093.2 23 65 29 101 203 NA NA NA NA NA NA 35240 XM_029340915.2 1240 986 622 918 564 P49406 3.82e-24 39S ribosomal protein L19, mitochondrial (L19mt) (MRP-L19) (39S ribosomal protein L15, mitochondrial) (L15mt) (MRP-L15) (Mitochondrial large ribosomal subunit protein bL19m) Homo sapiens (Human) mitochondrial translation [GO:0032543] GO:0003735; GO:0005634; GO:0005739; GO:0005743; GO:0005762; GO:0032543 35241 XM_029344847.2 3322 3485 1501 3218 1718 E1B836 1.15e-74 Enkurin Bos taurus (Bovine) establishment of left/right asymmetry [GO:0061966]; flagellated sperm motility [GO:0030317] GO:0001669; GO:0005516; GO:0005879; GO:0017124; GO:0030317; GO:0061966; GO:0097228; GO:0097728 35242 XM_044321879.1 3540 4508 4161 3328 2042 Q6TGS6 2.93e-154 Tyrosine--tRNA ligase, cytoplasmic (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to DNA damage stimulus [GO:0006974]; tyrosyl-tRNA aminoacylation [GO:0006437] GO:0000049; GO:0004831; GO:0005524; GO:0005634; GO:0005737; GO:0006437; GO:0006974 35243 XM_044320818.1 10 0 1 4 0 NA NA NA NA NA NA 35244 XR_006396509.1 128 26 32 0 49 NA NA NA NA NA NA 35245 XR_006393057.1 25 3 24 3 46 Q1LYL8 1.19e-25 Protein asteroid homolog 1 Danio rerio (Zebrafish) (Brachydanio rerio) NA NA 35246 XR_006393057.1 25 3 24 3 46 Q1LYL8 1.19e-25 Protein asteroid homolog 1 Danio rerio (Zebrafish) (Brachydanio rerio) NA NA 35247 XR_006393057.1 25 3 24 3 46 Q1LYL8 1.19e-25 Protein asteroid homolog 1 Danio rerio (Zebrafish) (Brachydanio rerio) NA NA 35248 XM_044329263.1 0 42 9 14 21 NA NA NA NA NA NA 35249 XM_029334745.2 704 934 1221 908 1032 Q6GL69 2.89e-54 MKI67 FHA domain-interacting nucleolar phosphoprotein-like Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0003723; GO:0005730 35250 XM_044317732.1 375 134 242 425 980 A6NMZ7 1.47e-55 Collagen alpha-6(VI) chain Homo sapiens (Human) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 35251 XM_044317732.1 375 134 242 425 980 A6NMZ7 7.07e-48 Collagen alpha-6(VI) chain Homo sapiens (Human) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 35252 XM_044317732.1 375 134 242 425 980 A6NMZ7 2.54e-41 Collagen alpha-6(VI) chain Homo sapiens (Human) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 35253 XM_044317732.1 375 134 242 425 980 A6NMZ7 9.67e-29 Collagen alpha-6(VI) chain Homo sapiens (Human) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 35254 XM_044317732.1 375 134 242 425 980 A6NMZ7 1.99e-26 Collagen alpha-6(VI) chain Homo sapiens (Human) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 35255 XM_044317732.1 375 134 242 425 980 A6NMZ7 3.25e-24 Collagen alpha-6(VI) chain Homo sapiens (Human) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 35256 XM_029341863.2 278 196 139 127 105 NA NA NA NA NA NA 35257 XM_044323120.1 24 24 0 9 0 NA NA NA NA NA NA 35258 XM_044314378.1 7 0 0 0 2 Q8NDA2 6.63e-27 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 35259 XM_044314378.1 7 0 0 0 2 Q8NDA2 5.67e-25 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 35260 XM_044314378.1 7 0 0 0 2 Q8NDA2 6.73e-21 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 35261 XM_029353358.2 114 23 61 17 266 NA NA NA NA NA NA 35262 XM_044320085.1 0 19 46 0 0 P18257 3.5e-59 Neuronal acetylcholine receptor subunit non-alpha-3 (GFN-alpha-3) Carassius auratus (Goldfish) NA GO:0004888; GO:0022848; GO:0045211 35263 XR_006391981.1 293 43 313 18 412 NA NA NA NA NA NA 35264 XM_044309001.1 79 159 54 100 86 NA NA NA NA NA NA 35265 XM_029339079.2 0 132 0 2 263 Q8N653 8.34e-25 Leucine-zipper-like transcriptional regulator 1 (LZTR-1) Homo sapiens (Human) negative regulation of Ras protein signal transduction [GO:0046580]; protein ubiquitination [GO:0016567] GO:0005794; GO:0012505; GO:0016567; GO:0031267; GO:0031463; GO:0046580; GO:0055038 35266 XM_029357605.2 324 310 93 359 160 A0A2B4RNI3 1.22e-27 NA NA NA NA 35267 XM_029333910.2 3007 2952 1758 2778 1897 NA NA NA NA NA NA 35268 XM_044319565.1 1559 1706 393 1168 614 NA NA NA NA NA NA 35269 XM_044319119.1 17 28 36 73 4 B0BN95 9.68e-30 Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease) Rattus norvegicus (Rat) NA GO:0004518; GO:0005634; GO:0005737; GO:0046872 35270 XM_044319107.1 20 0 0 0 1 NA NA NA NA NA NA 35271 XR_006395538.1 0 0 143 0 0 P53992 0 Protein transport protein Sec24C (SEC24-related protein C) Homo sapiens (Human) COPII-coated vesicle cargo loading [GO:0090110]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; in utero embryonic development [GO:0001701]; intracellular protein transport [GO:0006886] GO:0000149; GO:0001701; GO:0005789; GO:0005829; GO:0006886; GO:0006888; GO:0008270; GO:0012507; GO:0030127; GO:0070971; GO:0090110 35272 XM_044326201.1 120 3 26 188 45 NA NA NA NA NA NA 35273 XM_044328191.1 8 0 0 0 11 O43854 1.21e-23 EGF-like repeat and discoidin I-like domain-containing protein 3 (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1) Homo sapiens (Human) cell adhesion [GO:0007155]; positive regulation of cell-substrate adhesion [GO:0010811] GO:0005178; GO:0005509; GO:0007155; GO:0010811; GO:0062023; GO:0070062; GO:1903561 35274 XR_006392719.1 65 41 26 38 36 NA NA NA NA NA NA 35275 XM_029333510.2 76 11 119 176 187 Q61382 2.14e-50 TNF receptor-associated factor 4 (EC 2.3.2.27) (Cysteine-rich motif associated to RING and Traf domains protein 1) Mus musculus (Mouse) activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; innate immune response [GO:0045087]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein kinase activity [GO:0045860]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; respiratory gaseous exchange by respiratory system [GO:0007585]; respiratory tube development [GO:0030323] GO:0001650; GO:0005164; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0005923; GO:0006915; GO:0007250; GO:0007585; GO:0008270; GO:0016740; GO:0019901; GO:0030323; GO:0031625; GO:0031996; GO:0042802; GO:0042981; GO:0043122; GO:0043161; GO:0045087; GO:0045860; GO:0046330; GO:0048471; GO:0050699 35276 XM_044313361.1 1978 1229 1229 1890 1861 NA NA NA NA NA NA 35277 XM_029337352.2 40 38 0 62 0 NA NA NA NA NA NA 35278 XM_029339598.2 562 445 98 482 173 Q9W676 6.59e-141 LIM domain-binding protein 2 (LDB-2) (Carboxyl-terminal LIM domain-binding protein 1) (CLIM-1) (LIM domain-binding factor CLIM1) (cLdb2) Gallus gallus (Chicken) negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000122; GO:0005634; GO:0005667; GO:0007399; GO:0030274; GO:0045944 35279 XM_029335287.2 0 0 0 31 0 Q09694 2.05e-89 Saccharopine dehydrogenase [NAD(+), L-lysine-forming] (SDH) (EC 1.5.1.7) (Lysine--2-oxoglutarate reductase) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) lysine biosynthetic process [GO:0009085]; lysine biosynthetic process via aminoadipic acid [GO:0019878] GO:0004753; GO:0004754; GO:0005737; GO:0009085; GO:0019878 35280 XM_044321457.1 1032 896 930 685 453 Q14192 6.07e-64 Four and a half LIM domains protein 2 (FHL-2) (LIM domain protein DRAL) (Skeletal muscle LIM-protein 3) (SLIM-3) Homo sapiens (Human) atrial cardiac muscle cell development [GO:0055014]; heart trabecula formation [GO:0060347]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of transcription by RNA polymerase II [GO:0000122]; osteoblast differentiation [GO:0001649]; response to hormone [GO:0009725]; ventricular cardiac muscle cell development [GO:0055015] GO:0000122; GO:0001649; GO:0003712; GO:0003714; GO:0005634; GO:0005654; GO:0005925; GO:0008134; GO:0009725; GO:0030018; GO:0042802; GO:0043066; GO:0043425; GO:0046872; GO:0055014; GO:0055015; GO:0060347; GO:0070885 35281 XM_044321457.1 1032 896 930 685 453 Q14192 3.75e-34 Four and a half LIM domains protein 2 (FHL-2) (LIM domain protein DRAL) (Skeletal muscle LIM-protein 3) (SLIM-3) Homo sapiens (Human) atrial cardiac muscle cell development [GO:0055014]; heart trabecula formation [GO:0060347]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of transcription by RNA polymerase II [GO:0000122]; osteoblast differentiation [GO:0001649]; response to hormone [GO:0009725]; ventricular cardiac muscle cell development [GO:0055015] GO:0000122; GO:0001649; GO:0003712; GO:0003714; GO:0005634; GO:0005654; GO:0005925; GO:0008134; GO:0009725; GO:0030018; GO:0042802; GO:0043066; GO:0043425; GO:0046872; GO:0055014; GO:0055015; GO:0060347; GO:0070885 35282 XM_044321457.1 1032 896 930 685 453 Q14192 9.07e-25 Four and a half LIM domains protein 2 (FHL-2) (LIM domain protein DRAL) (Skeletal muscle LIM-protein 3) (SLIM-3) Homo sapiens (Human) atrial cardiac muscle cell development [GO:0055014]; heart trabecula formation [GO:0060347]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of transcription by RNA polymerase II [GO:0000122]; osteoblast differentiation [GO:0001649]; response to hormone [GO:0009725]; ventricular cardiac muscle cell development [GO:0055015] GO:0000122; GO:0001649; GO:0003712; GO:0003714; GO:0005634; GO:0005654; GO:0005925; GO:0008134; GO:0009725; GO:0030018; GO:0042802; GO:0043066; GO:0043425; GO:0046872; GO:0055014; GO:0055015; GO:0060347; GO:0070885 35283 XM_044321457.1 1032 896 930 685 453 Q14192 1.18e-23 Four and a half LIM domains protein 2 (FHL-2) (LIM domain protein DRAL) (Skeletal muscle LIM-protein 3) (SLIM-3) Homo sapiens (Human) atrial cardiac muscle cell development [GO:0055014]; heart trabecula formation [GO:0060347]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of transcription by RNA polymerase II [GO:0000122]; osteoblast differentiation [GO:0001649]; response to hormone [GO:0009725]; ventricular cardiac muscle cell development [GO:0055015] GO:0000122; GO:0001649; GO:0003712; GO:0003714; GO:0005634; GO:0005654; GO:0005925; GO:0008134; GO:0009725; GO:0030018; GO:0042802; GO:0043066; GO:0043425; GO:0046872; GO:0055014; GO:0055015; GO:0060347; GO:0070885 35284 XM_029330892.2 48 20 18 33 75 NA NA NA NA NA NA 35285 XM_044318881.1 65 31 102 13 180 NA NA NA NA NA NA 35286 XM_044312732.1 109 418 0 211 0 Q66HG5 0 Transmembrane 9 superfamily member 2 Rattus norvegicus (Rat) ceramide metabolic process [GO:0006672]; glycosphingolipid biosynthetic process [GO:0006688]; protein localization to membrane [GO:0072657]; regulation of heparan sulfate proteoglycan biosynthetic process [GO:0010908] GO:0005794; GO:0005856; GO:0006672; GO:0006688; GO:0010008; GO:0010908; GO:0016020; GO:0072657 35287 XR_006395892.1 278 53 351 76 760 Q66IB8 5.59e-40 UPF0538 protein C2orf76 homolog Danio rerio (Zebrafish) (Brachydanio rerio) NA NA 35288 XM_044317540.1 0 1 0 9 2 P29147 1.88e-71 D-beta-hydroxybutyrate dehydrogenase, mitochondrial (EC 1.1.1.30) (3-hydroxybutyrate dehydrogenase) (BDH) Rattus norvegicus (Rat) adipose tissue development [GO:0060612]; brain development [GO:0007420]; liver development [GO:0001889]; response to cadmium ion [GO:0046686]; response to corticosterone [GO:0051412]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to growth hormone [GO:0060416]; response to hormone [GO:0009725]; response to insulin [GO:0032868]; response to nutrient [GO:0007584]; response to starvation [GO:0042594]; response to toxic substance [GO:0009636]; response to xenobiotic stimulus [GO:0009410]; steroid metabolic process [GO:0008202] GO:0001889; GO:0003858; GO:0005543; GO:0005743; GO:0005759; GO:0007420; GO:0007584; GO:0008202; GO:0009410; GO:0009636; GO:0009725; GO:0016491; GO:0032355; GO:0032868; GO:0042594; GO:0043231; GO:0045471; GO:0046686; GO:0051412; GO:0060416; GO:0060612; GO:0099617 35289 XM_044317235.1 0 0 0 7 0 NA NA NA NA NA NA 35290 XM_044328661.1 128 149 17 96 138 P28606 6.27e-88 Uncharacterized protein SYNPCC7002_A1628 Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (Agmenellum quadruplicatum) histone deacetylation [GO:0016575] GO:0004407; GO:0016575 35291 XR_006391825.1 1 1 7 24 3 NA NA NA NA NA NA 35292 XM_029323598.2 4227 5432 3847 8970 5482 Q6P132 1.97e-36 Tax1-binding protein 1 homolog B Danio rerio (Zebrafish) (Brachydanio rerio) apoptotic process [GO:0006915] GO:0006915; GO:0046872 35293 XM_044319293.1 793 1693 526 628 902 Q502K2 0 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (dNTPase) (EC 3.1.5.-) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to DNA damage stimulus [GO:0006974]; dATP catabolic process [GO:0046061]; defense response to virus [GO:0051607]; deoxyribonucleotide catabolic process [GO:0009264]; dGTP catabolic process [GO:0006203]; DNA strand resection involved in replication fork processing [GO:0110025]; double-strand break repair via homologous recombination [GO:0000724]; innate immune response [GO:0045087]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; protein homotetramerization [GO:0051289]; regulation of innate immune response [GO:0045088]; somatic hypermutation of immunoglobulin genes [GO:0016446] GO:0000724; GO:0003676; GO:0003697; GO:0003723; GO:0005525; GO:0005634; GO:0006203; GO:0006974; GO:0008270; GO:0008832; GO:0009264; GO:0016446; GO:0016793; GO:0032567; GO:0035861; GO:0045087; GO:0045088; GO:0046061; GO:0051289; GO:0051607; GO:0060339; GO:0106375; GO:0110025 35294 XM_029338764.2 226 209 157 859 508 P42325 1.24e-119 Neurocalcin homolog (DrosNCa) Drosophila melanogaster (Fruit fly) negative regulation of neuronal signal transduction [GO:1902848]; positive regulation of circadian sleep/wake cycle, sleep [GO:0045938] GO:0005509; GO:0045938; GO:1902848 35295 XR_006393955.1 21 15 31 22 33 NA NA NA NA NA NA 35296 XM_044314243.1 0 74 0 0 0 NA NA NA NA NA NA 35297 XM_029345489.2 0 113 109 14 200 Q8N0W4 1.02e-77 Neuroligin-4, X-linked (Neuroligin X) (HNLX) Homo sapiens (Human) adult behavior [GO:0030534]; brainstem development [GO:0003360]; cell-cell junction organization [GO:0045216]; cerebellum development [GO:0021549]; chemical synaptic transmission [GO:0007268]; learning [GO:0007612]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of excitatory postsynaptic potential [GO:0090394]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; organ growth [GO:0035265]; postsynaptic membrane assembly [GO:0097104]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; social behavior [GO:0035176]; synapse organization [GO:0050808]; synaptic vesicle endocytosis [GO:0048488]; vocalization behavior [GO:0071625] GO:0003360; GO:0005886; GO:0007158; GO:0007268; GO:0007612; GO:0009986; GO:0016020; GO:0021549; GO:0030182; GO:0030425; GO:0030534; GO:0031404; GO:0035176; GO:0035265; GO:0038023; GO:0042043; GO:0042803; GO:0045202; GO:0045216; GO:0048488; GO:0050804; GO:0050808; GO:0050839; GO:0060076; GO:0071625; GO:0090394; GO:0097104; GO:0097105; GO:0097110; GO:0098793; GO:0098839; GO:0098983; GO:0098985; GO:0099054; GO:0099634 35298 XM_029336115.2 199 274 160 271 354 Q32NQ7 8.64e-134 Dynein axonemal assembly factor 3 Xenopus laevis (African clawed frog) axonemal dynein complex assembly [GO:0070286]; motile cilium assembly [GO:0044458] GO:0044458; GO:0070286; GO:0120293 35299 XM_044322853.1 88 29 0 193 146 NA NA NA NA NA NA 35300 XM_029346162.2 876 682 306 780 618 Q561P5 0 DNA replication licensing factor mcm5 (EC 3.6.4.12) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell cycle [GO:0007049]; DNA replication initiation [GO:0006270]; DNA unwinding involved in DNA replication [GO:0006268]; regulation of DNA-templated DNA replication initiation [GO:0030174] GO:0000785; GO:0003688; GO:0004386; GO:0005524; GO:0006268; GO:0006270; GO:0007049; GO:0016887; GO:0030174; GO:0042555; GO:0071162 35301 XM_029353819.2 1335 489 1021 1623 1718 NA NA NA NA NA NA 35302 XM_029356265.2 33 48 29 32 124 Q95108 1.2e-35 Thioredoxin, mitochondrial (MTRX) (Mt-Trx) (Thioredoxin-2) Bos taurus (Bovine) cell redox homeostasis [GO:0045454] GO:0005730; GO:0005739; GO:0015035; GO:0045454 35303 XM_044317847.1 411 371 449 522 387 NA NA NA NA NA NA 35304 XM_044307951.1 0 0 15 2 0 NA NA NA NA NA NA 35305 XM_029339835.2 69 0 0 28 218 NA NA NA NA NA NA 35306 XM_029324123.2 30 50 40 100 411 NA NA NA NA NA NA 35307 XM_029336111.2 1724 1317 902 1450 1234 Q2YDM0 3.98e-25 Transmembrane protein 248 Bos taurus (Bovine) NA GO:0016020 35308 XR_003826393.2 4385 6359 17357 47750 21425 NA NA NA NA NA NA 35309 XM_029341865.2 82 100 78 86 146 Q03555 9.56e-157 Gephyrin (Putative glycine receptor-tubulin linker protein) [Includes: Molybdopterin adenylyltransferase (MPT adenylyltransferase) (EC 2.7.7.75) (Domain G); Molybdopterin molybdenumtransferase (MPT Mo-transferase) (EC 2.10.1.1) (Domain E)] Rattus norvegicus (Rat) establishment of protein localization [GO:0045184]; establishment of synaptic specificity at neuromuscular junction [GO:0007529]; gamma-aminobutyric acid receptor clustering [GO:0097112]; glycine receptor clustering [GO:0072579]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein targeting [GO:0006605]; response to metal ion [GO:0010038]; synapse assembly [GO:0007416] GO:0005102; GO:0005524; GO:0005737; GO:0005829; GO:0005856; GO:0006605; GO:0006777; GO:0007416; GO:0007529; GO:0008940; GO:0010038; GO:0014069; GO:0015631; GO:0018315; GO:0030425; GO:0030674; GO:0031234; GO:0032324; GO:0042802; GO:0043025; GO:0043546; GO:0045184; GO:0045202; GO:0045211; GO:0046872; GO:0060077; GO:0060090; GO:0061598; GO:0061599; GO:0072579; GO:0097060; GO:0097112; GO:0098690; GO:0098794; GO:0098970; GO:0098982; GO:0099091; GO:0099572; GO:0099634; GO:0099645 35310 XM_029341865.2 82 100 78 86 146 Q03555 6.92e-49 Gephyrin (Putative glycine receptor-tubulin linker protein) [Includes: Molybdopterin adenylyltransferase (MPT adenylyltransferase) (EC 2.7.7.75) (Domain G); Molybdopterin molybdenumtransferase (MPT Mo-transferase) (EC 2.10.1.1) (Domain E)] Rattus norvegicus (Rat) establishment of protein localization [GO:0045184]; establishment of synaptic specificity at neuromuscular junction [GO:0007529]; gamma-aminobutyric acid receptor clustering [GO:0097112]; glycine receptor clustering [GO:0072579]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein targeting [GO:0006605]; response to metal ion [GO:0010038]; synapse assembly [GO:0007416] GO:0005102; GO:0005524; GO:0005737; GO:0005829; GO:0005856; GO:0006605; GO:0006777; GO:0007416; GO:0007529; GO:0008940; GO:0010038; GO:0014069; GO:0015631; GO:0018315; GO:0030425; GO:0030674; GO:0031234; GO:0032324; GO:0042802; GO:0043025; GO:0043546; GO:0045184; GO:0045202; GO:0045211; GO:0046872; GO:0060077; GO:0060090; GO:0061598; GO:0061599; GO:0072579; GO:0097060; GO:0097112; GO:0098690; GO:0098794; GO:0098970; GO:0098982; GO:0099091; GO:0099572; GO:0099634; GO:0099645 35311 XM_044329030.1 0 0 17 13 0 NA NA NA NA NA NA 35312 XR_003828453.2 0 0 4 9 8 NA NA NA NA NA NA 35313 XM_029356413.2 805 712 466 654 821 Q5ZMV7 2.06e-160 WD repeat-containing protein 82 Gallus gallus (Chicken) DNA-templated transcription termination [GO:0006353]; histone H3-K4 trimethylation [GO:0080182]; lncRNA catabolic process [GO:0110064]; negative regulation of DNA-templated transcription, elongation [GO:0032785]; negative regulation of lncRNA transcription [GO:0140744]; nuclear RNA surveillance [GO:0071027] GO:0003682; GO:0005694; GO:0006353; GO:0032785; GO:0048188; GO:0071027; GO:0080182; GO:0110064; GO:0140744 35314 XM_029339746.2 27 32 33 0 0 O88609 1e-74 LIM homeobox transcription factor 1-beta (LIM/homeobox protein 1.2) (LMX-1.2) (LIM/homeobox protein LMX1B) Mus musculus (Mouse) camera-type eye development [GO:0043010]; cell population proliferation [GO:0008283]; central nervous system neuron development [GO:0021954]; cerebellum morphogenesis [GO:0021587]; collagen fibril organization [GO:0030199]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral pattern formation [GO:0009953]; embryonic limb morphogenesis [GO:0030326]; limb morphogenesis [GO:0035108]; locomotory behavior [GO:0007626]; memory [GO:0007613]; midbrain development [GO:0030901]; neuron differentiation [GO:0030182]; neuron migration [GO:0001764]; olfactory behavior [GO:0042048]; organ growth [GO:0035265]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of autophagy [GO:0010506]; regulation of DNA-templated transcription [GO:0006355]; regulation of gene expression [GO:0010468]; regulation of intracellular transport [GO:0032386]; regulation of transcription by RNA polymerase II [GO:0006357]; synapse organization [GO:0050808]; trabecular meshwork development [GO:0002930] GO:0000977; GO:0000981; GO:0001228; GO:0001764; GO:0002930; GO:0003700; GO:0005634; GO:0006355; GO:0006357; GO:0007613; GO:0007626; GO:0008283; GO:0009953; GO:0010468; GO:0010506; GO:0021587; GO:0021954; GO:0030182; GO:0030199; GO:0030326; GO:0030901; GO:0032386; GO:0035108; GO:0035265; GO:0042048; GO:0043010; GO:0045944; GO:0046872; GO:0050808; GO:0071542; GO:1990837 35315 XM_029340470.2 243 203 104 177 195 NA NA NA NA NA NA 35316 XR_006391944.1 0 0 4 0 70 NA NA NA NA NA NA 35317 XM_044308535.1 39 37 65 198 186 P20825 3.89e-92 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 35318 XM_044326960.1 0 1 2 7 0 NA NA NA NA NA NA 35319 XR_006397691.1 0 0 0 212 227 NA NA NA NA NA NA 35320 XR_006397128.1 103 235 60 28 148 NA NA NA NA NA NA 35321 XM_044310275.1 1024 243 138 831 292 NA NA NA NA NA NA 35322 XR_003823193.2 16 59 34 43 86 NA NA NA NA NA NA 35323 XM_029337027.2 1086 924 638 1322 990 P17971 0 Potassium voltage-gated channel protein Shal (Shaker cognate l) (Shal2) Drosophila melanogaster (Fruit fly) associative learning [GO:0008306]; chemical synaptic transmission [GO:0007268]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005250; GO:0005886; GO:0006813; GO:0007268; GO:0008076; GO:0008306; GO:0016020; GO:0030425; GO:0034765; GO:0043204; GO:0045202; GO:0051260; GO:0071805 35324 XR_006397192.1 41 0 65 0 190 NA NA NA NA NA NA 35325 XM_044324699.1 29 79 9 25 21 NA NA NA NA NA NA 35326 XM_029327493.2 58 21 4 57 30 NA NA NA NA NA NA 35327 XM_044321150.1 3 12 0 0 27 Q9NYT0 2.39e-46 Pleckstrin-2 Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; intracellular signal transduction [GO:0035556]; positive regulation of plasma membrane bounded cell projection assembly [GO:0120034] GO:0005737; GO:0005856; GO:0005886; GO:0031258; GO:0031532; GO:0032266; GO:0035556; GO:0043325; GO:0080025; GO:0120034 35328 XM_029350360.2 729 475 438 823 643 Q9Z1Z0 0 General vesicular transport factor p115 (Protein USO1 homolog) (Transcytosis-associated protein) (TAP) (Vesicle-docking protein) Mus musculus (Mouse) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; Golgi vesicle docking [GO:0048211]; intracellular protein transport [GO:0006886]; membrane fusion [GO:0061025]; regulation of cellular response to insulin stimulus [GO:1900076]; secretory granule localization [GO:0032252]; small GTPase mediated signal transduction [GO:0007264]; transcytosis [GO:0045056]; vesicle fusion with Golgi apparatus [GO:0048280] GO:0000139; GO:0001650; GO:0005783; GO:0005794; GO:0005795; GO:0005829; GO:0006886; GO:0006888; GO:0007030; GO:0007264; GO:0012507; GO:0032252; GO:0045056; GO:0048211; GO:0048280; GO:0048471; GO:0061025; GO:1900076 35329 XM_044321915.1 14 47 43 69 20 Q8IRC7 1e-76 LIM/homeobox protein Awh (Protein arrowhead) Drosophila melanogaster (Fruit fly) compound eye development [GO:0048749]; imaginal disc development [GO:0007444]; neuron differentiation [GO:0030182]; regulation of DNA-templated transcription [GO:0006355]; regulation of gene expression [GO:0010468]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000977; GO:0000981; GO:0003700; GO:0005634; GO:0006355; GO:0006357; GO:0007444; GO:0010468; GO:0030182; GO:0046872; GO:0048749 35330 XM_044327108.1 126 0 33 0 0 NA NA NA NA NA NA 35331 XM_044326213.1 1593 2050 2172 2196 18288 A4IGL7 4.4e-88 Peroxidasin (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0005576; GO:0005604; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0031012; GO:0042744; GO:0046872; GO:0051260; GO:0070207; GO:0070831; GO:0071711; GO:0140825 35332 XM_029345793.2 229 284 141 184 180 Q1T7C0 1.1e-30 Centromere protein L (CENP-L) Gallus gallus (Chicken) NA GO:0000775; GO:0005634 35333 XM_029349966.2 0 0 0 7 0 B2RY50 1.49e-139 Outer dynein arm-docking complex subunit 2 (Armadillo repeat-containing protein 4) Mus musculus (Mouse) cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; outer dynein arm assembly [GO:0036158]; regulation of cilium beat frequency [GO:0003356]; ventricular system development [GO:0021591] GO:0003341; GO:0003356; GO:0005930; GO:0007368; GO:0007507; GO:0021591; GO:0036158; GO:0097546 35334 XM_044312804.1 26 2 27 5 14 NA NA NA NA NA NA 35335 XR_006391620.1 247 330 118 43 16 NA NA NA NA NA NA 35336 XM_044322637.1 21898 25378 14786 28550 13197 B3EWZ0 6.26e-51 Secreted acidic protein 1A Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 35337 XM_044315577.1 3 0 0 0 28 NA NA NA NA NA NA 35338 XM_029350977.2 97 233 77 110 36 Q08DH3 2.68e-52 Probable tRNA methyltransferase 9B (Probable tRNA methyltransferase 9-like protein) (EC 2.1.1.-) Bos taurus (Bovine) tRNA methylation [GO:0030488]; tRNA wobble uridine modification [GO:0002098] GO:0000049; GO:0002098; GO:0005634; GO:0005737; GO:0030488; GO:0106335 35339 XM_029346767.2 369 480 264 599 420 NA NA NA NA NA NA 35340 XR_006392980.1 41 2 25 5 151 NA NA NA NA NA NA 35341 XM_044324666.1 235 342 209 432 447 Q5RAL7 7.42e-28 UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1 (Beta-1,3-GalNAc-T1) (EC 2.4.1.79) (Beta-1,3-galactosyltransferase 3) (Beta-1,3-GalTase 3) (Beta3Gal-T3) (Beta3GalT3) (b3Gal-T3) (Beta-3-Gx-T3) (Galactosylgalactosylglucosylceramide beta-D-acetyl-galactosaminyltransferase) (Globoside synthase) (UDP-N-acetylgalactosamine:globotriaosylceramide beta-1,3-N-acetylgalactosaminyltransferase) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) lipid metabolic process [GO:0006629]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0006629; GO:0047273 35342 XM_044310870.1 0 1 0 18 19 NA NA NA NA NA NA 35343 XM_029333824.2 48 128 40 79 65 F1QCP6 4.68e-86 Tafazzin (Taz) (EC 2.3.1.-) Danio rerio (Zebrafish) (Brachydanio rerio) cardiolipin acyl-chain remodeling [GO:0035965]; cardiolipin metabolic process [GO:0032048]; heart development [GO:0007507]; heart looping [GO:0001947]; inner mitochondrial membrane organization [GO:0007007]; mitophagy [GO:0000423]; positive regulation of heart contraction [GO:0045823] GO:0000423; GO:0001947; GO:0005739; GO:0005741; GO:0005743; GO:0007007; GO:0007507; GO:0008374; GO:0031966; GO:0032048; GO:0035965; GO:0045823; GO:0047184 35344 XR_006396408.1 29 18 32 9 44 NA NA NA NA NA NA 35345 XR_006397086.1 39 23 8 35 46 NA NA NA NA NA NA 35346 XM_029329695.2 240 158 135 175 277 Q80Y56 3.86e-95 Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (RAB effector RBSN) (Zinc finger FYVE domain-containing protein 20) Mus musculus (Mouse) early endosome to Golgi transport [GO:0034498]; Golgi to lysosome transport [GO:0090160]; protein transport [GO:0015031]; regulation of Golgi organization [GO:1903358] GO:0005829; GO:0005886; GO:0015031; GO:0031267; GO:0031901; GO:0034498; GO:0043231; GO:0046872; GO:0090160; GO:1903358 35347 XM_044324612.1 226 250 115 129 168 NA NA NA NA NA NA 35348 XM_029342290.2 58 60 34 44 78 Q6TDP4 1.57e-59 Kelch-like protein 17 (Actinfilin) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; protein ubiquitination [GO:0016567]; regulation protein catabolic process at postsynapse [GO:0140252] GO:0005615; GO:0007420; GO:0014069; GO:0015629; GO:0016567; GO:0030036; GO:0031208; GO:0032839; GO:0043025; GO:0051015; GO:0060090; GO:0098978; GO:0140252 35349 XM_044316735.1 206 0 205 178 255 NA NA NA NA NA NA 35350 XM_044323525.1 1111 1193 1007 939 896 NA NA NA NA NA NA 35351 XM_029335207.2 624 321 287 399 665 Q1LU86 2.28e-38 CBY1-interacting BAR domain-containing protein 1 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; inner mitochondrial membrane organization [GO:0007007]; positive regulation of smoothened signaling pathway [GO:0045880] GO:0005634; GO:0005737; GO:0005743; GO:0005814; GO:0005929; GO:0007007; GO:0019898; GO:0035869; GO:0036064; GO:0045880; GO:0060271; GO:0097546 35352 XM_044319857.1 0 2 1 7 1 NA NA NA NA NA NA 35353 XM_044310187.1 5 3 102 60 89 Q80XJ3 1.24e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 35354 XM_029328972.2 531 174 216 805 682 Q5R5M5 3.78e-155 Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 (E-NPP 3) (Phosphodiesterase I beta) (PD-Ibeta) (Phosphodiesterase I/nucleotide pyrophosphatase 3) (CD antigen CD203c) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (NPPase) (EC 3.6.1.9) (Nucleotide diphosphatase)] Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) ATP metabolic process [GO:0046034]; basophil activation involved in immune response [GO:0002276]; negative regulation of inflammatory response [GO:0050728]; negative regulation of mast cell activation involved in immune response [GO:0033007]; negative regulation of mast cell proliferation [GO:0070667]; pyrimidine nucleotide metabolic process [GO:0006220] GO:0002276; GO:0003676; GO:0004528; GO:0005509; GO:0005576; GO:0006220; GO:0008270; GO:0009897; GO:0016324; GO:0033007; GO:0046034; GO:0047429; GO:0050728; GO:0070667 35355 XM_029340499.2 994 823 430 909 597 A0JMY4 8.68e-135 Basal body-orientation factor 1 (Coiled-coil domain-containing protein 176) Xenopus laevis (African clawed frog) motile cilium assembly [GO:0044458] GO:0005737; GO:0036064; GO:0044458 35356 XM_044317157.1 6 0 0 0 0 P81139 4.65e-72 Pancreatic lipase-related protein 2 (PL-RP2) (Cytotoxic T lymphocyte lipase) (GPL) (Galactolipase) (EC 3.1.1.26) (Triacylglycerol lipase) (EC 3.1.1.3) Cavia porcellus (Guinea pig) galactolipid catabolic process [GO:0019376]; lipid metabolic process [GO:0006629]; phospholipid catabolic process [GO:0009395]; phospholipid metabolic process [GO:0006644]; triglyceride catabolic process [GO:0019433] GO:0004620; GO:0004806; GO:0005509; GO:0005615; GO:0006629; GO:0006644; GO:0009395; GO:0016020; GO:0019376; GO:0019433; GO:0031410; GO:0043005; GO:0047372; GO:0047714; GO:0102549 35357 XM_044327571.1 373 418 108 428 280 Q13257 7.14e-74 Mitotic spindle assembly checkpoint protein MAD2A (HsMAD2) (Mitotic arrest deficient 2-like protein 1) (MAD2-like protein 1) Homo sapiens (Human) cell division [GO:0051301]; establishment of centrosome localization [GO:0051660]; establishment of mitotic spindle orientation [GO:0000132]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint signaling [GO:0007094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of ubiquitin protein ligase activity [GO:1904667]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267] GO:0000070; GO:0000132; GO:0000776; GO:0000922; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0007094; GO:0008022; GO:0033597; GO:0042177; GO:0042802; GO:0042803; GO:0043066; GO:0044615; GO:0045930; GO:0048471; GO:0051301; GO:0051444; GO:0051660; GO:0072686; GO:0090267; GO:1904667; GO:1990728 35358 XM_044316650.1 23 22 51 58 127 NA NA NA NA NA NA 35359 XM_044311399.1 12 16 29 7 28 NA NA NA NA NA NA 35360 XM_029330248.2 132 322 253 308 65 NA NA NA NA NA NA 35361 XM_029355512.2 0 0 0 49 0 P11362 1.4e-63 Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331) Homo sapiens (Human) cell migration [GO:0016477]; chordate embryonic development [GO:0043009]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; MAPK cascade [GO:0000165]; neuron migration [GO:0001764]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell differentiation [GO:0045595]; regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001239]; skeletal system development [GO:0001501]; skeletal system morphogenesis [GO:0048705]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0000165; GO:0001501; GO:0001764; GO:0001837; GO:0004713; GO:0004714; GO:0005007; GO:0005524; GO:0005576; GO:0005634; GO:0005829; GO:0005886; GO:0006468; GO:0007169; GO:0008201; GO:0008284; GO:0008543; GO:0010518; GO:0010863; GO:0014068; GO:0016020; GO:0016477; GO:0017134; GO:0018108; GO:0031410; GO:0033674; GO:0042802; GO:0042803; GO:0043009; GO:0043235; GO:0043406; GO:0043410; GO:0043536; GO:0045595; GO:0045597; GO:0045666; GO:0046777; GO:0048015; GO:0048705; GO:0051897; GO:0090722; GO:1905564; GO:2000546; GO:2001239 35362 XM_029343008.2 753 649 585 849 710 Q0V989 1.83e-43 Coiled-coil domain-containing protein 85C Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005912; GO:0005923 35363 XM_044318513.1 130 56 54 0 0 NA NA NA NA NA NA 35364 XM_029341971.2 711 441 377 563 391 NA NA NA NA NA NA 35365 XM_044324843.1 524 0 47 57 0 Q9WVF7 0 DNA polymerase epsilon catalytic subunit A (EC 2.7.7.7) (3'-5' exodeoxyribonuclease) (EC 3.1.11.-) (DNA polymerase II subunit A) Mus musculus (Mouse) base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; DNA replication proofreading [GO:0045004]; DNA synthesis involved in DNA repair [GO:0000731]; DNA-templated DNA replication [GO:0006261]; embryonic organ development [GO:0048568]; G1/S transition of mitotic cell cycle [GO:0000082]; leading strand elongation [GO:0006272]; mitotic cell cycle [GO:0000278]; nucleotide-excision repair, DNA gap filling [GO:0006297] GO:0000082; GO:0000166; GO:0000278; GO:0000731; GO:0003677; GO:0003682; GO:0003887; GO:0005634; GO:0005654; GO:0005886; GO:0006260; GO:0006261; GO:0006272; GO:0006287; GO:0006297; GO:0008270; GO:0008310; GO:0008622; GO:0045004; GO:0048568; GO:0051539; GO:0071897 35366 XM_044315654.1 0 0 0 5 7 NA NA NA NA NA NA 35367 XM_044310635.1 33 12 43 19 26 NA NA NA NA NA NA 35368 XM_029332934.2 1360 794 690 1294 1222 Q6NYY9 1.89e-140 Vacuole membrane protein 1 Danio rerio (Zebrafish) (Brachydanio rerio) autophagy [GO:0006914]; Golgi organization [GO:0007030]; lipoprotein transport [GO:0042953] GO:0005774; GO:0005783; GO:0005789; GO:0005886; GO:0006914; GO:0007030; GO:0012505; GO:0016020; GO:0017128; GO:0033116; GO:0042953 35369 XM_029341667.2 970 1555 606 795 942 Q6UX73 1.72e-29 UPF0764 protein C16orf89 Homo sapiens (Human) NA GO:0005829; GO:0016020; GO:0042803; GO:0070062 35370 XM_044322907.1 0 132 49 258 471 Q9VLC0 5.75e-169 Vacuolar protein sorting-associated protein 54 (Protein scattered) Drosophila melanogaster (Fruit fly) acrosome assembly [GO:0001675]; endocytic recycling [GO:0032456]; Golgi to vacuole transport [GO:0006896]; protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147]; sperm individualization [GO:0007291]; spermatid nucleus elongation [GO:0007290] GO:0000138; GO:0000938; GO:0001675; GO:0005794; GO:0005829; GO:0006896; GO:0007290; GO:0007291; GO:0015031; GO:0019905; GO:0032456; GO:0042147 35371 XM_044326159.1 8 0 0 0 7 NA NA NA NA NA NA 35372 XR_006392110.1 28 6 16 6 80 NA NA NA NA NA NA 35373 XM_029343782.2 794 477 332 570 532 P05183 1.28e-96 Cytochrome P450 3A2 (EC 1.14.14.1) (CYPIIIA2) (Cytochrome P450-PCN2) (Cytochrome P450/6-beta-A) (Testosterone 6-beta-hydroxylase) Rattus norvegicus (Rat) alkaloid catabolic process [GO:0009822]; estrogen metabolic process [GO:0008210]; heterocycle metabolic process [GO:0046483]; lipid hydroxylation [GO:0002933]; monoterpenoid metabolic process [GO:0016098]; oxidative demethylation [GO:0070989]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]; steroid catabolic process [GO:0006706]; steroid metabolic process [GO:0008202]; vitamin D catabolic process [GO:0042369]; xenobiotic catabolic process [GO:0042178]; xenobiotic metabolic process [GO:0006805] GO:0002933; GO:0004497; GO:0005496; GO:0005506; GO:0005737; GO:0005789; GO:0006706; GO:0006805; GO:0008202; GO:0008210; GO:0008395; GO:0008401; GO:0009822; GO:0016098; GO:0016491; GO:0019899; GO:0020037; GO:0030343; GO:0032451; GO:0034875; GO:0042178; GO:0042369; GO:0042572; GO:0042573; GO:0046483; GO:0050649; GO:0062181; GO:0070330; GO:0070576; GO:0070989; GO:0101020; GO:0101021 35374 XM_044320930.1 195 4 6 191 128 NA NA NA NA NA NA 35375 XM_029347043.2 3458 3980 2804 2212 1664 Q9NUS5 1.33e-27 AP-5 complex subunit sigma-1 (Adaptor-related protein complex 5 sigma subunit) (Sigma5) Homo sapiens (Human) double-strand break repair via homologous recombination [GO:0000724]; endosomal transport [GO:0016197]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] GO:0000724; GO:0005654; GO:0005764; GO:0005765; GO:0005770; GO:0005829; GO:0015031; GO:0016192; GO:0016197; GO:0030119; GO:0031902; GO:0044599 35376 XM_044315875.1 18 0 1 6 5 Q80XJ3 5.9e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 35377 XM_029339378.2 755 986 1142 1309 626 NA NA NA NA NA NA 35378 XM_029330982.2 57 18 28 42 57 Q62623 4.17e-159 Cell division cycle protein 20 homolog (p55CDC) Rattus norvegicus (Rat) anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; mitotic sister chromatid cohesion [GO:0007064]; mitotic spindle assembly [GO:0090307]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; positive regulation of anaphase-promoting complex-dependent catabolic process [GO:1905786]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of synapse maturation [GO:0090129]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; protein ubiquitination [GO:0016567]; regulation of dendrite development [GO:0050773]; regulation of meiotic nuclear division [GO:0040020] GO:0000922; GO:0005654; GO:0005680; GO:0005813; GO:0005829; GO:0007064; GO:0008022; GO:0008284; GO:0010997; GO:0016567; GO:0019899; GO:0031145; GO:0031915; GO:0032991; GO:0033597; GO:0040020; GO:0042826; GO:0048471; GO:0050773; GO:0051301; GO:0051444; GO:0090129; GO:0090307; GO:1904668; GO:1905786; GO:1990757 35379 XM_029345540.2 94 176 44245 69 49 NA NA NA NA NA NA 35380 XM_029345961.2 293 85 101 241 258 O15439 0 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 35381 XM_029326308.2 1045 675 604 831 1066 Q6MG55 1.32e-135 Phosphatidylserine lipase ABHD16A (EC 3.1.-.-) (Alpha/beta hydrolase domain-containing protein 16A) (Abhydrolase domain-containing protein 16A) (HLA-B-associated transcript 5 homolog) (Monoacylglycerol lipase ABHD16A) (EC 3.1.1.23) Rattus norvegicus (Rat) monoacylglycerol catabolic process [GO:0052651]; phosphatidylserine catabolic process [GO:0006660]; prostaglandin catabolic process [GO:1905344] GO:0004620; GO:0006660; GO:0008474; GO:0016020; GO:0047372; GO:0052651; GO:1905344 35382 XM_029332101.2 0 27 56 9 41 NA NA NA NA NA NA 35383 XM_044316632.1 0 0 0 26 0 NA NA NA NA NA NA 35384 XM_044310231.1 74 217 108 68 541 NA NA NA NA NA NA 35385 XM_029332922.2 895 248 247 580 626 Q6GVH4 6.16e-165 Gametogenetin-binding protein 2 (Protein ZNF403) Gallus gallus (Chicken) cell differentiation [GO:0030154]; spermatogenesis [GO:0007283] GO:0005634; GO:0005737; GO:0007283; GO:0030154 35386 XM_044324946.1 60 2 8 25 15 NA NA NA NA NA NA 35387 XM_029335880.2 487 469 333 405 392 Q8N1S5 1.57e-125 Zinc transporter ZIP11 (Solute carrier family 39 member 11) (Zrt- and Irt-like protein 11) (ZIP-11) Homo sapiens (Human) zinc ion transmembrane transport [GO:0071577] GO:0005385; GO:0005634; GO:0005737; GO:0005794; GO:0005886; GO:0016020; GO:0071577 35388 XR_006396827.1 14 0 30 18 75 NA NA NA NA NA NA 35389 XR_003827074.2 19 3 27 14 27 NA NA NA NA NA NA 35390 XM_044328226.1 63 273 68 65 81 Q8K2J9 7.79e-73 BTB/POZ domain-containing protein 6 Mus musculus (Mouse) neurogenesis [GO:0022008] GO:0005829; GO:0022008 35391 XM_044328614.1 0 3 6 0 0 Q49SH1 9.35e-89 Sodium/potassium/calcium exchanger 5 (Na(+)/K(+)/Ca(2+)-exchange protein 5) (Protein golden) (Solute carrier family 24 member 5) Danio rerio (Zebrafish) (Brachydanio rerio) calcium ion transport [GO:0006816]; potassium ion transport [GO:0006813]; response to stimulus [GO:0050896]; sodium ion transport [GO:0006814] GO:0005794; GO:0006813; GO:0006814; GO:0006816; GO:0015293; GO:0015297; GO:0016020; GO:0042470; GO:0050896 35392 XM_044313018.1 0 0 0 0 42 P22300 2.38e-39 Gamma-aminobutyric acid receptor subunit gamma-2 (GABA(A) receptor subunit gamma-2) Bos taurus (Bovine) cellular response to histamine [GO:0071420]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid signaling pathway [GO:0007214]; inhibitory synapse assembly [GO:1904862] GO:0004890; GO:0005230; GO:0005254; GO:0005886; GO:0007214; GO:0030425; GO:0030659; GO:0034707; GO:0045211; GO:0071420; GO:1902476; GO:1902711; GO:1904862 35393 XM_044318734.1 727 595 505 841 534 B0S5D5 2.73e-52 Palmitoyltransferase ZDHHC12-A (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 12-A) Danio rerio (Zebrafish) (Brachydanio rerio) peptidyl-L-cysteine S-palmitoylation [GO:0018230]; protein targeting to membrane [GO:0006612] GO:0000139; GO:0005783; GO:0005789; GO:0005794; GO:0006612; GO:0018230; GO:0019706 35394 XM_044327362.1 14 5 1 2 5 NA NA NA NA NA NA 35395 XM_029330401.2 1644 1037 734 1173 1053 A2A432 0 Cullin-4B (CUL-4B) Mus musculus (Mouse) astrocyte differentiation [GO:0048708]; cell cycle [GO:0007049]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; gene expression [GO:0010467]; histone H2A monoubiquitination [GO:0035518]; neuron projection development [GO:0031175]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of protein catabolic process [GO:0045732]; proteasomal protein catabolic process [GO:0010498]; protein ubiquitination [GO:0016567]; ribosome biogenesis [GO:0042254]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; UV-damage excision repair [GO:0070914] GO:0003684; GO:0005634; GO:0005654; GO:0005829; GO:0006974; GO:0007049; GO:0010467; GO:0010498; GO:0016567; GO:0030674; GO:0031146; GO:0031175; GO:0031461; GO:0031464; GO:0031465; GO:0031625; GO:0034644; GO:0035518; GO:0042254; GO:0045732; GO:0048708; GO:0070914; GO:0080008; GO:1900087 35396 XM_029343019.2 1086 744 692 1030 801 A4IIL4 8.78e-135 BRO1 domain-containing protein BROX (BRO1 domain- and CAAX motif-containing protein) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0016020 35397 XM_044321244.1 101 45 46 44 43 NA NA NA NA NA NA 35398 XM_044308221.1 78 27 14 27 34 Q80TC6 0 Zinc finger SWIM domain-containing protein 5 Mus musculus (Mouse) NA GO:0008270; GO:0031462 35399 XM_044324129.1 13 3 1 1 2 NA NA NA NA NA NA 35400 XM_029346694.2 4 3 2 0 15 NA NA NA NA NA NA 35401 XM_044329150.1 44 21 13 24 87 P30974 1.45e-25 Tachykinin-like peptides receptor 86C (NKD) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; inter-male aggressive behavior [GO:0002121]; neuropeptide signaling pathway [GO:0007218]; tachykinin receptor signaling pathway [GO:0007217] GO:0002121; GO:0004995; GO:0005886; GO:0007186; GO:0007217; GO:0007218; GO:0008188; GO:0016020 35402 XM_029328902.2 1609 1432 1441 1411 1457 Q28DB0 1.65e-121 Tetratricopeptide repeat protein 39B (TPR repeat protein 39B) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) lipid metabolic process [GO:0006629] GO:0006629 35403 XM_029353105.2 7 5 4 0 26 NA NA NA NA NA NA 35404 XM_029323597.2 930 501 345 444 690 Q4V7W3 1.16e-30 Protein HEXIM1 Xenopus laevis (African clawed frog) negative regulation of transcription by RNA polymerase II [GO:0000122] GO:0000122; GO:0004861; GO:0005634; GO:0005737; GO:0017069 35405 XM_044326859.1 0 0 0 29 119 Q75N90 3.7e-45 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 35406 XM_044326859.1 0 0 0 29 119 Q75N90 9.74e-39 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 35407 XM_044326859.1 0 0 0 29 119 Q75N90 4.27e-33 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 35408 XM_044326859.1 0 0 0 29 119 Q75N90 5.34e-32 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 35409 XM_044326859.1 0 0 0 29 119 Q75N90 1.97e-28 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 35410 XM_044326859.1 0 0 0 29 119 Q75N90 2.11e-28 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 35411 XM_044326859.1 0 0 0 29 119 Q75N90 6.11e-28 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 35412 XM_044326859.1 0 0 0 29 119 Q75N90 1.15e-26 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 35413 XM_044326859.1 0 0 0 29 119 Q75N90 1.91e-23 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 35414 XM_044326859.1 0 0 0 29 119 Q75N90 4.34e-23 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 35415 XM_044326859.1 0 0 0 29 119 Q75N90 2.09e-22 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 35416 XM_044326859.1 0 0 0 29 119 Q75N90 4.87e-22 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 35417 XM_044326859.1 0 0 0 29 119 Q75N90 1.18e-21 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 35418 XM_029344931.2 144 80 172 104 223 Q61473 5.9e-30 Transcription factor SOX-17 Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; cardiac cell fate determination [GO:0060913]; cardiogenic plate morphogenesis [GO:0003142]; cell differentiation [GO:0030154]; cell migration involved in gastrulation [GO:0042074]; cellular response to leukemia inhibitory factor [GO:1990830]; common bile duct development [GO:0061009]; embryonic foregut morphogenesis [GO:0048617]; embryonic heart tube development [GO:0035050]; embryonic heart tube morphogenesis [GO:0003143]; embryonic organ development [GO:0048568]; endocardial cell differentiation [GO:0060956]; endocardium formation [GO:0060214]; endoderm development [GO:0007492]; endoderm formation [GO:0001706]; endodermal cell differentiation [GO:0035987]; endodermal cell fate determination [GO:0007493]; endodermal cell fate specification [GO:0001714]; endodermal digestive tract morphogenesis [GO:0061031]; gallbladder development [GO:0061010]; gastrulation [GO:0007369]; gene expression [GO:0010467]; heart development [GO:0007507]; heart looping [GO:0001947]; inner cell mass cellular morphogenesis [GO:0001828]; metanephros development [GO:0001656]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell growth [GO:0030308]; negative regulation of Wnt signaling pathway [GO:0030178]; negative regulation of Wnt signaling pathway involved in heart development [GO:0003308]; outflow tract morphogenesis [GO:0003151]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of endodermal cell differentiation [GO:1903226]; positive regulation of gene expression [GO:0010628]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of stem cell differentiation [GO:2000738]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein destabilization [GO:0031648]; protein stabilization [GO:0050821]; regulation of cardiac cell fate specification [GO:2000043]; regulation of cell differentiation [GO:0045595]; regulation of DNA-templated transcription [GO:0006355]; regulation of embryonic development [GO:0045995]; regulation of stem cell division [GO:2000035]; regulation of stem cell proliferation [GO:0072091]; regulation of transcription by RNA polymerase II [GO:0006357]; rostrocaudal neural tube patterning [GO:0021903]; signal transduction involved in regulation of gene expression [GO:0023019]; spermatogenesis [GO:0007283]; stem cell differentiation [GO:0048863]; stem cell fate specification [GO:0048866]; ureter development [GO:0072189]; vasculogenesis [GO:0001570]; Wnt signaling pathway [GO:0016055] GO:0000976; GO:0000978; GO:0000981; GO:0001228; GO:0001525; GO:0001570; GO:0001656; GO:0001706; GO:0001714; GO:0001828; GO:0001947; GO:0003142; GO:0003143; GO:0003151; GO:0003308; GO:0003677; GO:0003700; GO:0005634; GO:0005667; GO:0006355; GO:0006357; GO:0007283; GO:0007369; GO:0007492; GO:0007493; GO:0007507; GO:0008013; GO:0009653; GO:0010467; GO:0010628; GO:0016055; GO:0021903; GO:0023019; GO:0030154; GO:0030178; GO:0030308; GO:0031648; GO:0035050; GO:0035987; GO:0042074; GO:0043565; GO:0045595; GO:0045732; GO:0045893; GO:0045944; GO:0045995; GO:0048568; GO:0048617; GO:0048863; GO:0048866; GO:0050821; GO:0060214; GO:0060913; GO:0060956; GO:0061009; GO:0061010; GO:0061031; GO:0061629; GO:0072091; GO:0072189; GO:0090090; GO:1903226; GO:1990830; GO:2000035; GO:2000043; GO:2000738 35419 XM_044314282.1 30 7 29 16 6 NA NA NA NA NA NA 35420 XM_029333932.2 205 303 258 221 324 NA NA NA NA NA NA 35421 XM_044323128.1 3 6 6 4 22 NA NA NA NA NA NA 35422 XM_044307725.1 92 155 0 61 0 Q9D565 0 WD repeat-containing protein 64 Mus musculus (Mouse) NA NA 35423 XM_029341263.2 1054 1397 576 1244 2007 NA NA NA NA NA NA 35424 XM_044316673.1 0 20 71 0 0 Q8R3B7 3.47e-59 Bromodomain-containing protein 8 Mus musculus (Mouse) cellular response to thyroid hormone stimulus [GO:0097067]; chromatin organization [GO:0006325]; histone acetylation [GO:0016573]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of double-strand break repair [GO:2000779] GO:0000786; GO:0000812; GO:0005654; GO:0005739; GO:0006325; GO:0016573; GO:0030374; GO:0035267; GO:0042981; GO:0043967; GO:0043968; GO:0045893; GO:0045944; GO:0046966; GO:0051726; GO:0097067; GO:1905168; GO:2000779 35425 XM_044316673.1 0 20 71 0 0 Q8R3B7 1.37e-38 Bromodomain-containing protein 8 Mus musculus (Mouse) cellular response to thyroid hormone stimulus [GO:0097067]; chromatin organization [GO:0006325]; histone acetylation [GO:0016573]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of double-strand break repair [GO:2000779] GO:0000786; GO:0000812; GO:0005654; GO:0005739; GO:0006325; GO:0016573; GO:0030374; GO:0035267; GO:0042981; GO:0043967; GO:0043968; GO:0045893; GO:0045944; GO:0046966; GO:0051726; GO:0097067; GO:1905168; GO:2000779 35426 XM_029334451.2 195 438 504 823 1728 Q9UPV9 2.22e-50 Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase-interacting protein) (Protein Milton) Homo sapiens (Human) anterograde axonal transport of mitochondrion [GO:0098957]; endosome to lysosome transport [GO:0008333]; mitochondrion distribution [GO:0048311]; neurogenesis [GO:0022008]; protein O-linked glycosylation [GO:0006493]; protein targeting [GO:0006605]; regulation of transcription by RNA polymerase II [GO:0006357]; vesicle transport along microtubule [GO:0047496] GO:0005102; GO:0005634; GO:0005737; GO:0005739; GO:0005769; GO:0005829; GO:0005938; GO:0006357; GO:0006493; GO:0006605; GO:0008333; GO:0017022; GO:0022008; GO:0030425; GO:0031410; GO:0031966; GO:0047496; GO:0048311; GO:0050811; GO:0098957; GO:1904115 35427 XM_044326595.1 2 19 0 0 0 Q91ZV7 5.8e-51 Plexin domain-containing protein 1 (Tumor endothelial marker 7) Mus musculus (Mouse) spinal cord development [GO:0021510] GO:0005737; GO:0005886; GO:0005923; GO:0021510; GO:0030425; GO:0043025; GO:0043235 35428 XM_029323717.2 0 47 0 47 0 P25931 4.83e-28 RYamide receptor (Neuropeptide Y-like receptor) (NPY-R) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218] GO:0001653; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0016020 35429 XR_003824334.2 0 21 0 0 44 NA NA NA NA NA NA 35430 XM_029355468.2 383 316 98 164 126 Q5RJU3 1.84e-44 Coiled-coil domain-containing protein 103 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) axonemal dynein complex assembly [GO:0070286] GO:0031514; GO:0036157; GO:0070286 35431 XM_044324933.1 15 11 0 37 38 Q9ULM3 2.16e-64 YEATS domain-containing protein 2 Homo sapiens (Human) chromatin remodeling [GO:0006338]; histone acetylation [GO:0016573]; histone H3 acetylation [GO:0043966]; histone H3-K14 acetylation [GO:0044154]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of cell cycle [GO:0051726]; regulation of cell division [GO:0051302]; regulation of DNA-templated transcription [GO:0006355]; regulation of embryonic development [GO:0045995]; regulation of histone deacetylation [GO:0031063]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tubulin deacetylation [GO:0090043] GO:0000122; GO:0005634; GO:0006338; GO:0006355; GO:0006357; GO:0016573; GO:0017025; GO:0031063; GO:0035267; GO:0042393; GO:0043966; GO:0044154; GO:0045892; GO:0045995; GO:0051302; GO:0051726; GO:0072686; GO:0090043; GO:0140030; GO:0140672 35432 XR_003827031.2 49 1 62 53 188 NA NA NA NA NA NA 35433 XM_044320299.1 446 238 288 451 342 Q8VHT8 5.79e-71 Transcription factor IIIA (TFIIIA) Rattus norvegicus (Rat) ribosomal large subunit biogenesis [GO:0042273] GO:0000995; GO:0003677; GO:0005634; GO:0008097; GO:0042273; GO:0046872 35434 XM_044323695.1 0 0 0 7 0 NA NA NA NA NA NA 35435 XM_029346532.2 830 447 500 714 873 P32297 8.39e-93 Neuronal acetylcholine receptor subunit alpha-3 Homo sapiens (Human) acetylcholine receptor signaling pathway [GO:0095500]; activation of transmembrane receptor protein tyrosine kinase activity [GO:0007171]; behavioral response to nicotine [GO:0035095]; chemical synaptic transmission [GO:0007268]; excitatory postsynaptic potential [GO:0060079]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; locomotory behavior [GO:0007626]; membrane depolarization [GO:0051899]; nervous system development [GO:0007399]; nervous system process [GO:0050877]; regulation of acetylcholine secretion, neurotransmission [GO:0014056]; regulation of dendrite morphogenesis [GO:0048814]; regulation of membrane potential [GO:0042391]; regulation of smooth muscle contraction [GO:0006940]; response to acetylcholine [GO:1905144]; signal transduction [GO:0007165]; synaptic transmission involved in micturition [GO:0060084]; synaptic transmission, cholinergic [GO:0007271] GO:0005231; GO:0005886; GO:0005892; GO:0006811; GO:0006940; GO:0007165; GO:0007171; GO:0007268; GO:0007271; GO:0007399; GO:0007626; GO:0014056; GO:0014069; GO:0015276; GO:0015464; GO:0016020; GO:0016607; GO:0022848; GO:0030425; GO:0030594; GO:0034220; GO:0035095; GO:0042166; GO:0042391; GO:0043005; GO:0043025; GO:0044853; GO:0045202; GO:0045211; GO:0048814; GO:0050877; GO:0051899; GO:0060079; GO:0060084; GO:0095500; GO:1904315; GO:1905144 35436 XM_044329110.1 3 4 2 2 7 NA NA NA NA NA NA 35437 XM_029332516.2 1044 690 1371 3642 2238 Q8CGY8 0 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.255) (O-GlcNAc transferase subunit p110) (O-linked N-acetylglucosamine transferase 110 kDa subunit) (OGT) Mus musculus (Mouse) apoptotic process [GO:0006915]; cellular response to glucose stimulus [GO:0071333]; cellular response to lipopolysaccharide [GO:0071222]; chromatin organization [GO:0006325]; circadian regulation of gene expression [GO:0032922]; glucosamine metabolic process [GO:0006041]; hemopoiesis [GO:0030097]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; intracellular distribution of mitochondria [GO:0048312]; mitophagy [GO:0000423]; negative regulation of cell death [GO:0060548]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular response to hypoxia [GO:1900038]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein targeting to membrane [GO:0090315]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of stem cell population maintenance [GO:1902455]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cell size [GO:0045793]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of histone H3-K27 methylation [GO:0061087]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of proteolysis [GO:0045862]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein O-linked glycosylation [GO:0006493]; protein processing [GO:0016485]; regulation of dosage compensation by inactivation of X chromosome [GO:1900095]; regulation of gluconeogenesis [GO:0006111]; regulation of glycolytic process [GO:0006110]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of Rac protein signal transduction [GO:0035020]; regulation of synapse assembly [GO:0051963]; regulation of transcription by RNA polymerase II [GO:0006357]; response to insulin [GO:0032868] GO:0000122; GO:0000123; GO:0000423; GO:0000791; GO:0001933; GO:0001934; GO:0003824; GO:0005547; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005829; GO:0005886; GO:0006041; GO:0006110; GO:0006111; GO:0006325; GO:0006357; GO:0006493; GO:0006915; GO:0008080; GO:0010628; GO:0010801; GO:0016485; GO:0016580; GO:0017122; GO:0019904; GO:0030097; GO:0030336; GO:0030512; GO:0031397; GO:0031490; GO:0031966; GO:0032435; GO:0032868; GO:0032922; GO:0032991; GO:0033137; GO:0035020; GO:0042277; GO:0042588; GO:0042802; GO:0043005; GO:0043025; GO:0043981; GO:0043982; GO:0043984; GO:0044545; GO:0044877; GO:0045202; GO:0045793; GO:0045862; GO:0045893; GO:0045944; GO:0046626; GO:0048015; GO:0048312; GO:0051571; GO:0051963; GO:0060548; GO:0061087; GO:0071222; GO:0071333; GO:0090315; GO:0097363; GO:0098696; GO:0098978; GO:0098982; GO:0099523; GO:0099524; GO:0120162; GO:0150048; GO:1900038; GO:1900095; GO:1900182; GO:1902455; GO:1902459; GO:1903428 35438 XM_029332516.2 1044 690 1371 3642 2238 Q8CGY8 1.91e-51 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.255) (O-GlcNAc transferase subunit p110) (O-linked N-acetylglucosamine transferase 110 kDa subunit) (OGT) Mus musculus (Mouse) apoptotic process [GO:0006915]; cellular response to glucose stimulus [GO:0071333]; cellular response to lipopolysaccharide [GO:0071222]; chromatin organization [GO:0006325]; circadian regulation of gene expression [GO:0032922]; glucosamine metabolic process [GO:0006041]; hemopoiesis [GO:0030097]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; intracellular distribution of mitochondria [GO:0048312]; mitophagy [GO:0000423]; negative regulation of cell death [GO:0060548]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular response to hypoxia [GO:1900038]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein targeting to membrane [GO:0090315]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of stem cell population maintenance [GO:1902455]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cell size [GO:0045793]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of histone H3-K27 methylation [GO:0061087]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of proteolysis [GO:0045862]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein O-linked glycosylation [GO:0006493]; protein processing [GO:0016485]; regulation of dosage compensation by inactivation of X chromosome [GO:1900095]; regulation of gluconeogenesis [GO:0006111]; regulation of glycolytic process [GO:0006110]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of Rac protein signal transduction [GO:0035020]; regulation of synapse assembly [GO:0051963]; regulation of transcription by RNA polymerase II [GO:0006357]; response to insulin [GO:0032868] GO:0000122; GO:0000123; GO:0000423; GO:0000791; GO:0001933; GO:0001934; GO:0003824; GO:0005547; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005829; GO:0005886; GO:0006041; GO:0006110; GO:0006111; GO:0006325; GO:0006357; GO:0006493; GO:0006915; GO:0008080; GO:0010628; GO:0010801; GO:0016485; GO:0016580; GO:0017122; GO:0019904; GO:0030097; GO:0030336; GO:0030512; GO:0031397; GO:0031490; GO:0031966; GO:0032435; GO:0032868; GO:0032922; GO:0032991; GO:0033137; GO:0035020; GO:0042277; GO:0042588; GO:0042802; GO:0043005; GO:0043025; GO:0043981; GO:0043982; GO:0043984; GO:0044545; GO:0044877; GO:0045202; GO:0045793; GO:0045862; GO:0045893; GO:0045944; GO:0046626; GO:0048015; GO:0048312; GO:0051571; GO:0051963; GO:0060548; GO:0061087; GO:0071222; GO:0071333; GO:0090315; GO:0097363; GO:0098696; GO:0098978; GO:0098982; GO:0099523; GO:0099524; GO:0120162; GO:0150048; GO:1900038; GO:1900095; GO:1900182; GO:1902455; GO:1902459; GO:1903428 35439 XM_029337664.2 914 544 536 751 829 Q9BY11 1.07e-71 Protein kinase C and casein kinase substrate in neurons protein 1 (Syndapin-1) Homo sapiens (Human) actin filament organization [GO:0007015]; cytoskeleton organization [GO:0007010]; negative regulation of endocytosis [GO:0045806]; neuron projection morphogenesis [GO:0048812]; plasma membrane tubulation [GO:0097320]; positive regulation of dendrite development [GO:1900006]; protein localization to membrane [GO:0072657]; protein localization to plasma membrane [GO:0072659]; regulation of endocytosis [GO:0030100]; synaptic vesicle endocytosis [GO:0048488] GO:0005543; GO:0005737; GO:0005768; GO:0005829; GO:0005886; GO:0007010; GO:0007015; GO:0008092; GO:0030100; GO:0030137; GO:0030659; GO:0032587; GO:0042802; GO:0043679; GO:0045202; GO:0045806; GO:0048471; GO:0048488; GO:0048812; GO:0072657; GO:0072659; GO:0097320; GO:0098684; GO:0098833; GO:1900006 35440 XM_029332091.2 3753 1788 1162 2894 2729 P49282 0 Natural resistance-associated macrophage protein 2 (NRAMP 2) (Divalent cation transporter 1) (Divalent metal transporter 1) (DMT-1) (Solute carrier family 11 member 2) Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cadmium ion transmembrane transport [GO:0070574]; cellular response to oxidative stress [GO:0034599]; cobalt ion transport [GO:0006824]; copper ion import across plasma membrane [GO:0098705]; copper ion transport [GO:0006825]; dendrite morphogenesis [GO:0048813]; erythrocyte development [GO:0048821]; establishment of localization in cell [GO:0051649]; heme biosynthetic process [GO:0006783]; iron import into cell [GO:0033212]; iron ion transmembrane transport [GO:0034755]; iron ion transport [GO:0006826]; lead ion transport [GO:0015692]; learning or memory [GO:0007611]; manganese ion transport [GO:0006828]; multicellular organismal iron ion homeostasis [GO:0060586]; nickel cation transport [GO:0015675]; porphyrin-containing compound biosynthetic process [GO:0006779]; porphyrin-containing compound metabolic process [GO:0006778]; response to hypoxia [GO:0001666]; response to iron ion [GO:0010039]; response to manganese ion [GO:0010042]; transition metal ion transport [GO:0000041]; vanadium ion transport [GO:0015676] GO:0000041; GO:0001666; GO:0005375; GO:0005381; GO:0005384; GO:0005506; GO:0005507; GO:0005634; GO:0005737; GO:0005739; GO:0005741; GO:0005764; GO:0005765; GO:0005768; GO:0005769; GO:0005770; GO:0005773; GO:0005802; GO:0005886; GO:0006778; GO:0006779; GO:0006783; GO:0006824; GO:0006825; GO:0006826; GO:0006828; GO:0006919; GO:0007611; GO:0008270; GO:0009986; GO:0010039; GO:0010042; GO:0015086; GO:0015087; GO:0015093; GO:0015094; GO:0015099; GO:0015100; GO:0015295; GO:0015675; GO:0015676; GO:0015692; GO:0016020; GO:0016151; GO:0016324; GO:0022890; GO:0030145; GO:0031410; GO:0031526; GO:0031902; GO:0033212; GO:0034599; GO:0034755; GO:0045177; GO:0045178; GO:0046870; GO:0046915; GO:0048471; GO:0048813; GO:0048821; GO:0050897; GO:0051649; GO:0055037; GO:0060586; GO:0070574; GO:0070826; GO:0098705; GO:1903561; GO:1905394 35441 XM_044325820.1 13 0 13 0 38 NA NA NA NA NA NA 35442 XM_044327686.1 265 300 267 485 694 Q7RTR2 4.91e-42 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 35443 XM_044327686.1 265 300 267 485 694 Q7RTR2 2.05e-26 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 35444 XM_044327686.1 265 300 267 485 694 Q7RTR2 3.15e-23 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 35445 XM_044328995.1 7 43 29 68 0 F1R332 3.52e-25 Galanin receptor 2a Danio rerio (Zebrafish) (Brachydanio rerio) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; neuropeptide signaling pathway [GO:0007218] GO:0004966; GO:0005886; GO:0007188; GO:0007218; GO:0008528 35446 XM_029328529.2 542 614 445 524 456 Q6PIP5 2.28e-105 NudC domain-containing protein 1 Mus musculus (Mouse) NA GO:0005654; GO:0005829 35447 XM_044312128.1 0 0 0 0 6 NA NA NA NA NA NA 35448 XM_029343996.2 536 607 309 686 721 P97739 7.54e-148 Endothelin-converting enzyme 1 (ECE-1) (EC 3.4.24.71) Cavia porcellus (Guinea pig) proteolysis [GO:0006508] GO:0004222; GO:0005886; GO:0006508; GO:0046872 35449 XM_029355556.2 253 114 104 123 210 NA NA NA NA NA NA 35450 XM_044308091.1 0 0 0 248 620 O00471 0 Exocyst complex component 5 (Exocyst complex component Sec10) (hSec10) Homo sapiens (Human) epithelial cell apoptotic process [GO:1904019]; establishment of planar polarity [GO:0001736]; exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; membrane fission [GO:0090148]; mitotic cytokinesis [GO:0000281]; non-motile cilium assembly [GO:1905515]; post-Golgi vesicle-mediated transport [GO:0006892]; protein localization to plasma membrane [GO:0072659]; protein transport [GO:0015031]; vesicle docking involved in exocytosis [GO:0006904]; vesicle tethering involved in exocytosis [GO:0090522] GO:0000145; GO:0000281; GO:0001736; GO:0005737; GO:0005829; GO:0006887; GO:0006892; GO:0006893; GO:0006904; GO:0015031; GO:0030496; GO:0031267; GO:0047485; GO:0072659; GO:0090148; GO:0090522; GO:1904019; GO:1905515 35451 XM_044316531.1 253 633 83 257 390 Q8BS35 1.28e-151 Alkylglycerol monooxygenase (EC 1.14.16.5) (Transmembrane protein 195) Mus musculus (Mouse) ether lipid metabolic process [GO:0046485]; lipid biosynthetic process [GO:0008610]; membrane lipid metabolic process [GO:0006643] GO:0005506; GO:0005783; GO:0005789; GO:0006643; GO:0008610; GO:0046485; GO:0050479 35452 XM_029344457.2 79 26 50 44 22 NA NA NA NA NA NA 35453 XM_029341563.2 196 26 0 82 49 Q9P107 1.09e-97 GEM-interacting protein (GMIP) Homo sapiens (Human) activation of GTPase activity [GO:0090630]; intracellular signal transduction [GO:0035556]; negative regulation of GTPase activity [GO:0034260]; regulation of small GTPase mediated signal transduction [GO:0051056] GO:0005096; GO:0005654; GO:0005829; GO:0005886; GO:0034260; GO:0035556; GO:0046872; GO:0051056; GO:0090630 35454 XM_044313029.1 117 148 4 31 18 Q96AY4 1.37e-63 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35455 XM_044313029.1 117 148 4 31 18 Q96AY4 1.87e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35456 XM_044313029.1 117 148 4 31 18 Q96AY4 1.11e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35457 XM_044313029.1 117 148 4 31 18 Q96AY4 4.96e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35458 XM_044313029.1 117 148 4 31 18 Q96AY4 1.45e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35459 XM_044313029.1 117 148 4 31 18 Q96AY4 1.12e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35460 XM_044313029.1 117 148 4 31 18 Q96AY4 1.54e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35461 XM_044313029.1 117 148 4 31 18 Q96AY4 1.37e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35462 XM_044313029.1 117 148 4 31 18 Q96AY4 6.28e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35463 XM_044313029.1 117 148 4 31 18 Q96AY4 5.87e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35464 XM_044313029.1 117 148 4 31 18 Q96AY4 1.1e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35465 XM_029338144.2 63 73 97 177 51 NA NA NA NA NA NA 35466 XM_044324321.1 456 211 392 216 465 Q1W1Y5 1e-57 Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of non-genomic activity of estrogen receptor) Macaca mulatta (Rhesus macaque) cellular response to estrogen stimulus [GO:0071391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; rRNA processing [GO:0006364] GO:0000791; GO:0003682; GO:0005634; GO:0005730; GO:0005737; GO:0006364; GO:0045944; GO:0071339; GO:0071391 35467 XR_006397966.1 69 3 15 6 19 NA NA NA NA NA NA 35468 XM_044319090.1 127 0 94 152 21 NA NA NA NA NA NA 35469 XM_044315216.1 0 0 0 0 47 NA NA NA NA NA NA 35470 XM_044314880.1 0 4 2 0 19 NA NA NA NA NA NA 35471 XM_029342443.2 0 0 201 0 5 B9EJV3 6.02e-122 GREB1-like protein Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cardiac ventricle development [GO:0003231]; epithelial tube morphogenesis [GO:0060562]; kidney development [GO:0001822]; male genitalia development [GO:0030539]; mesonephric duct development [GO:0072177]; metanephros development [GO:0001656]; paramesonephric duct development [GO:0061205]; uterus development [GO:0060065] GO:0001656; GO:0001658; GO:0001822; GO:0003231; GO:0016020; GO:0030539; GO:0060065; GO:0060562; GO:0061205; GO:0072177 35472 XM_029342443.2 0 0 201 0 5 B9EJV3 7.48e-96 GREB1-like protein Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cardiac ventricle development [GO:0003231]; epithelial tube morphogenesis [GO:0060562]; kidney development [GO:0001822]; male genitalia development [GO:0030539]; mesonephric duct development [GO:0072177]; metanephros development [GO:0001656]; paramesonephric duct development [GO:0061205]; uterus development [GO:0060065] GO:0001656; GO:0001658; GO:0001822; GO:0003231; GO:0016020; GO:0030539; GO:0060065; GO:0060562; GO:0061205; GO:0072177 35473 XM_029342443.2 0 0 201 0 5 B9EJV3 7.9e-42 GREB1-like protein Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cardiac ventricle development [GO:0003231]; epithelial tube morphogenesis [GO:0060562]; kidney development [GO:0001822]; male genitalia development [GO:0030539]; mesonephric duct development [GO:0072177]; metanephros development [GO:0001656]; paramesonephric duct development [GO:0061205]; uterus development [GO:0060065] GO:0001656; GO:0001658; GO:0001822; GO:0003231; GO:0016020; GO:0030539; GO:0060065; GO:0060562; GO:0061205; GO:0072177 35474 XM_044321164.1 15 1 6 11 34 NA NA NA NA NA NA 35475 XM_044312764.1 62 42 90 44 85 Q09325 1.49e-147 Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (EC 2.4.1.101) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I) (GNT-I) (GlcNAc-T I) Rattus norvegicus (Rat) in utero embryonic development [GO:0001701]; protein glycosylation [GO:0006486]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279]; UDP-N-acetylglucosamine catabolic process [GO:0006049] GO:0000139; GO:0001701; GO:0003827; GO:0005794; GO:0006049; GO:0006486; GO:0006487; GO:0008375; GO:0018279; GO:0030145; GO:0048471 35476 XM_029335491.2 308 198 42 263 253 Q9H3E2 0 Sorting nexin-25 Homo sapiens (Human) negative regulation of pathway-restricted SMAD protein phosphorylation [GO:0060394]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; protein transport [GO:0015031]; receptor catabolic process [GO:0032801] GO:0005768; GO:0010008; GO:0015031; GO:0030512; GO:0032801; GO:0035091; GO:0043231; GO:0060394 35477 XM_029347401.2 0 67 24 0 586 O13267 1.27e-90 Protein Wnt-5a (PWnt-5a) Pleurodeles waltl (Iberian ribbed newt) anatomical structure development [GO:0048856]; Wnt signaling pathway [GO:0016055] GO:0005102; GO:0005576; GO:0016055; GO:0048856 35478 XM_029344624.2 11 17 25 0 75 Q5R5U3 9.92e-104 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 35479 XM_029344624.2 11 17 25 0 75 Q5R5U3 3.25e-99 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 35480 XM_029344624.2 11 17 25 0 75 Q5R5U3 3.03e-45 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 35481 XM_029344624.2 11 17 25 0 75 Q5R5U3 1.05e-31 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 35482 XM_029346970.2 10 2 27 5 50 NA NA NA NA NA NA 35483 XM_029339201.2 525 678 515 474 407 NA NA NA NA NA NA 35484 XM_029336588.2 51 110 62 109 117 NA NA NA NA NA NA 35485 XM_029353813.2 1736 2233 2248 1899 774 Q9D8N3 1.17e-56 Lysoplasmalogenase-like protein TMEM86A (Transmembrane protein 86A) Mus musculus (Mouse) NA GO:0016020; GO:0047408; GO:0047409 35486 XM_029333914.2 628 626 332 731 564 NA NA NA NA NA NA 35487 XM_029333242.2 0 0 0 0 12 Q16281 0 Cyclic nucleotide-gated cation channel alpha-3 (Cone photoreceptor cGMP-gated channel subunit alpha) (Cyclic nucleotide-gated channel alpha-3) (CNG channel alpha-3) (CNG-3) (CNG3) Homo sapiens (Human) cation transmembrane transport [GO:0098655]; cation transport [GO:0006812]; inorganic cation import across plasma membrane [GO:0098659]; response to cAMP [GO:0051591]; response to corticosteroid [GO:0031960]; response to magnesium ion [GO:0032026]; signal transduction [GO:0007165]; visual perception [GO:0007601] GO:0005222; GO:0005223; GO:0005737; GO:0005886; GO:0006812; GO:0007165; GO:0007601; GO:0008022; GO:0015276; GO:0017071; GO:0030425; GO:0030553; GO:0031960; GO:0032026; GO:0043194; GO:0043204; GO:0044877; GO:0051591; GO:0097386; GO:0098655; GO:0098659; GO:1902495 35488 XM_029337515.2 683 714 350 545 486 Q8L7C9 2.17e-31 Glutathione S-transferase U20 (AtGSTU20) (EC 2.5.1.18) (FIN219-interacting protein 1) (GST class-tau member 20) Arabidopsis thaliana (Mouse-ear cress) glutathione metabolic process [GO:0006749]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407] GO:0004364; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0006749; GO:0009407; GO:0009507; GO:0009629; GO:0019899; GO:0043295; GO:0048046; GO:2000030 35489 XM_029329588.2 1361 837 1054 1374 1266 Q8BYF6 1.36e-135 Sodium-coupled monocarboxylate transporter 1 (Electrogenic sodium monocarboxylate cotransporter) (Solute carrier family 5 member 8) Mus musculus (Mouse) apoptotic process [GO:0006915]; monocarboxylic acid transport [GO:0015718]; propanoate transport [GO:0015730]; short-chain fatty acid import [GO:0015913]; sodium ion transport [GO:0006814] GO:0005343; GO:0006814; GO:0006915; GO:0015129; GO:0015293; GO:0015552; GO:0015636; GO:0015718; GO:0015730; GO:0015913; GO:0016324; GO:0031526; GO:0140161 35490 XR_006395992.1 134 129 29 165 127 NA NA NA NA NA NA 35491 XM_029334551.2 569 358 290 884 677 E9Q5F9 2.06e-103 Histone-lysine N-methyltransferase SETD2 (EC 2.1.1.359) (Lysine N-methyltransferase 3A) (Protein-lysine N-methyltransferase SETD2) (EC 2.1.1.-) (SET domain-containing protein 2) Mus musculus (Mouse) angiogenesis [GO:0001525]; cell migration involved in vasculogenesis [GO:0035441]; coronary vasculature morphogenesis [GO:0060977]; defense response to virus [GO:0051607]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic organ development [GO:0048568]; embryonic placenta morphogenesis [GO:0060669]; endodermal cell differentiation [GO:0035987]; forebrain development [GO:0030900]; histone H3-K36 dimethylation [GO:0097676]; histone H3-K36 trimethylation [GO:0097198]; mesoderm morphogenesis [GO:0048332]; microtubule cytoskeleton organization involved in mitosis [GO:1902850]; mismatch repair [GO:0006298]; morphogenesis of a branching structure [GO:0001763]; neural tube closure [GO:0001843]; nucleosome organization [GO:0034728]; peptidyl-lysine trimethylation [GO:0018023]; pericardium development [GO:0060039]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of ossification [GO:0045778]; regulation of cytokinesis [GO:0032465]; regulation of DNA-templated transcription [GO:0006355]; regulation of double-strand break repair via homologous recombination [GO:0010569]; regulation of gene expression [GO:0010468]; regulation of mRNA export from nucleus [GO:0010793]; regulation of protein localization to chromatin [GO:1905634]; response to type I interferon [GO:0034340]; stem cell development [GO:0048864]; stem cell differentiation [GO:0048863]; transcription elongation by RNA polymerase II promoter [GO:0006368]; vasculogenesis [GO:0001570] GO:0001525; GO:0001570; GO:0001763; GO:0001843; GO:0005634; GO:0005694; GO:0006298; GO:0006355; GO:0006368; GO:0010468; GO:0010569; GO:0010793; GO:0016279; GO:0018023; GO:0030900; GO:0032465; GO:0032727; GO:0034340; GO:0034728; GO:0035441; GO:0035987; GO:0043014; GO:0045778; GO:0046872; GO:0046975; GO:0048332; GO:0048568; GO:0048701; GO:0048863; GO:0048864; GO:0051607; GO:0060039; GO:0060669; GO:0060977; GO:0097198; GO:0097676; GO:0140955; GO:1902850; GO:1905634 35492 XM_029342820.2 7 5 0 3 6 NA NA NA NA NA NA 35493 XM_029355298.2 407 103 37 93 9 Q9Y2S2 6.15e-87 Lambda-crystallin homolog (EC 1.1.1.45) (L-gulonate 3-dehydrogenase) (Gul3DH) Homo sapiens (Human) fatty acid metabolic process [GO:0006631]; glucuronate catabolic process to xylulose 5-phosphate [GO:0019640] GO:0005829; GO:0006631; GO:0016491; GO:0019640; GO:0042803; GO:0050104; GO:0070062; GO:0070403 35494 XM_044321666.1 20 8 0 20 1 NA NA NA NA NA NA 35495 XM_044313259.1 0 0 141 202 343 A2AP18 0 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-eta-2) (Phosphoinositide phospholipase C-like 4) (PLC-L4) (Phospholipase C-like protein 4) (Phospholipase C-eta-2) (PLC-eta2) Mus musculus (Mouse) lipid catabolic process [GO:0016042]; phosphatidylinositol metabolic process [GO:0046488]; phosphatidylinositol-mediated signaling [GO:0048015] GO:0004435; GO:0004629; GO:0005509; GO:0005737; GO:0005886; GO:0016042; GO:0046488; GO:0048015 35496 XM_029357099.2 8141 6596 3880 8547 6720 Q7L0R7 7.33e-31 RING finger protein 44 Homo sapiens (Human) protein ubiquitination [GO:0016567] GO:0016567; GO:0046872; GO:0061630 35497 XM_044316955.1 456 331 136 495 663 Q5ZIA5 0 Coatomer subunit beta (Beta-coat protein) (Beta-COP) Gallus gallus (Chicken) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886] GO:0000139; GO:0005198; GO:0005829; GO:0006886; GO:0006888; GO:0006891; GO:0030126 35498 XM_044325786.1 34 11 22 0 24 NA NA NA NA NA NA 35499 XM_044326426.1 316 190 202 424 671 Q9NVE4 7.95e-28 Coiled-coil domain-containing protein 87 Homo sapiens (Human) cell differentiation [GO:0030154]; positive regulation of acrosome reaction [GO:2000344]; positive regulation of fertilization [GO:1905516]; single fertilization [GO:0007338]; spermatogenesis [GO:0007283] GO:0007283; GO:0007338; GO:0030154; GO:1905516; GO:2000344 35500 XM_044321158.1 3 6 5 11 21 NA NA NA NA NA NA 35501 XM_029327598.2 22 24 77 33 47 NA NA NA NA NA NA 35502 XM_029357573.2 1236 2207 451 1157 595 O95639 1.38e-114 Cleavage and polyadenylation specificity factor subunit 4 (Cleavage and polyadenylation specificity factor 30 kDa subunit) (CPSF 30 kDa subunit) (NS1 effector domain-binding protein 1) (Neb-1) (No arches homolog) Homo sapiens (Human) pre-mRNA cleavage required for polyadenylation [GO:0098789] GO:0003723; GO:0005654; GO:0005847; GO:0008270; GO:0043231; GO:0098789; GO:1990837 35503 XM_029332064.2 454 334 217 384 333 NA NA NA NA NA NA 35504 XM_029333923.2 139 54 101 192 160 NA NA NA NA NA NA 35505 XR_006397885.1 0 2 6 0 0 NA NA NA NA NA NA 35506 XR_003823829.2 12 5 0 0 12 NA NA NA NA NA NA 35507 XM_029345988.2 298 97 53 203 76 NA NA NA NA NA NA 35508 XR_006397881.1 47 40 0 0 13 NA NA NA NA NA NA 35509 XM_044324091.1 4 283 0 151 0 NA NA NA NA NA NA 35510 XM_044307052.1 95 47 104 74 73 NA NA NA NA NA NA 35511 XM_029332996.2 1267 1003 1091 880 2835 NA NA NA NA NA NA 35512 XM_029349141.2 1884 1444 720 919 591 O16025 0 Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (AOS) (EC 4.2.1.-) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)] Plexaura homomalla (Black sea rod) arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; lipid oxidation [GO:0034440]; oxylipin biosynthetic process [GO:0031408] GO:0005506; GO:0005737; GO:0006633; GO:0009978; GO:0016020; GO:0019369; GO:0020037; GO:0031408; GO:0034440; GO:0047677 35513 XM_029343845.2 25 10 13 51 30 NA NA NA NA NA NA 35514 XM_044307539.1 0 13 0 12 13 NA NA NA NA NA NA 35515 XM_044317742.1 49 50 24 158 33 Q08DY9 3.84e-35 Caspase-3 (CASP-3) (EC 3.4.22.56) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12] Bos taurus (Bovine) positive regulation of amyloid-beta formation [GO:1902004]; proteolysis [GO:0006508]; regulation of protein stability [GO:0031647] GO:0004175; GO:0005737; GO:0006508; GO:0031647; GO:0097153; GO:0097199; GO:0097200; GO:1902004 35516 XM_044320901.1 78 217 141 380 174 Q3ZBV2 9.4e-163 ATP-dependent RNA helicase DDX19A (EC 3.6.4.13) (DEAD box protein 19A) Bos taurus (Bovine) poly(A)+ mRNA export from nucleus [GO:0016973] GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005654; GO:0010494; GO:0016887; GO:0016973 35517 XM_029329594.2 1790 1243 1007 1688 1860 P59750 0 Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) Papio anubis (Olive baboon) actin cytoskeleton organization [GO:0030036]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; MAPK cascade [GO:0000165]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of osteoblast proliferation [GO:0033689]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of Schwann cell proliferation [GO:0010626]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; osteoblast proliferation [GO:0033687]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010] GO:0000165; GO:0001707; GO:0001726; GO:0003779; GO:0005730; GO:0005769; GO:0005829; GO:0005912; GO:0006469; GO:0007398; GO:0010626; GO:0014010; GO:0021766; GO:0022408; GO:0030027; GO:0030036; GO:0030175; GO:0030864; GO:0031647; GO:0032154; GO:0033687; GO:0033689; GO:0035330; GO:0042475; GO:0042532; GO:0042981; GO:0043005; GO:0043409; GO:0044297; GO:0045177; GO:0045216; GO:0045597; GO:0048471; GO:0051496; GO:0051726; GO:0070306; GO:0072091; GO:1900180; GO:2000177 35518 XM_029356870.2 19 0 0 0 0 NA NA NA NA NA NA 35519 XR_006391534.1 60 0 0 22 51 NA NA NA NA NA NA 35520 XM_044320565.1 0 0 253 0 0 NA NA NA NA NA NA 35521 XR_006392611.1 23 1 8 0 7 NA NA NA NA NA NA 35522 XR_006393423.1 43 0 85 22 180 NA NA NA NA NA NA 35523 XM_044321071.1 565 334 215 413 179 Q96RW7 7.29e-57 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 35524 XM_044321071.1 565 334 215 413 179 Q96RW7 1.93e-56 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 35525 XM_044321071.1 565 334 215 413 179 Q96RW7 3.73e-50 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 35526 XM_044315943.1 12 11 22 10 19 NA NA NA NA NA NA 35527 XM_029330708.2 1099 1189 739 960 553 B5FZ63 2.36e-35 Transcription and mRNA export factor ENY2 (Enhancer of yellow 2 transcription factor homolog) Taeniopygia guttata (Zebra finch) (Poephila guttata) chromatin organization [GO:0006325]; histone H3 acetylation [GO:0043966]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; poly(A)+ mRNA export from nucleus [GO:0016973]; positive regulation of DNA-templated transcription [GO:0045893]; protein transport [GO:0015031]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription elongation by RNA polymerase II promoter [GO:0006368] GO:0000124; GO:0003713; GO:0005654; GO:0005739; GO:0006325; GO:0006357; GO:0006368; GO:0015031; GO:0016973; GO:0030374; GO:0035522; GO:0043966; GO:0044615; GO:0045893; GO:0070390; GO:0071819 35528 XR_006393094.1 142 3 3 0 70 NA NA NA NA NA NA 35529 XR_006393092.1 94 3 56 31 298 NA NA NA NA NA NA 35530 XM_029329271.2 129 14 13 45 107 NA NA NA NA NA NA 35531 XM_029355343.2 924 537 327 126 54 Q14AT5 0 Anoctamin-7 (New gene expressed in prostate homolog) (Transmembrane protein 16G) Mus musculus (Mouse) calcium activated galactosylceramide scrambling [GO:0061591]; calcium activated phosphatidylcholine scrambling [GO:0061590]; calcium activated phosphatidylserine scrambling [GO:0061589]; calcium activated phospholipid scrambling [GO:0061588]; chloride transmembrane transport [GO:1902476]; chloride transport [GO:0006821]; establishment of localization in cell [GO:0051649]; transmembrane transport [GO:0055085] GO:0005254; GO:0005783; GO:0005886; GO:0006821; GO:0017128; GO:0046983; GO:0051649; GO:0055085; GO:0061588; GO:0061589; GO:0061590; GO:0061591; GO:1902476 35532 XR_006393778.1 2 1 12 2 23 NA NA NA NA NA NA 35533 XM_044307395.1 21 6 7 4 22 Q29555 1.12e-106 Glycine N-methyltransferase (EC 2.1.1.20) Sus scrofa (Pig) methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein homotetramerization [GO:0051289]; regulation of gluconeogenesis [GO:0006111]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; sarcosine metabolic process [GO:1901052] GO:0005542; GO:0005829; GO:0006111; GO:0006730; GO:0016594; GO:0017174; GO:0032259; GO:0042802; GO:0046498; GO:0046500; GO:0051289; GO:1901052; GO:1904047 35534 XM_044318132.1 8 0 7 5 0 NA NA NA NA NA NA 35535 XR_006392804.1 24 0 21 53 0 NA NA NA NA NA NA 35536 XM_029342914.2 150 58 88 89 131 P82094 1.43e-118 TATA element modulatory factor (TMF) (Androgen receptor coactivator 160 kDa protein) (Androgen receptor-associated protein of 160 kDa) Homo sapiens (Human) acrosome assembly [GO:0001675]; androgen receptor signaling pathway [GO:0030521]; defense response to bacterium [GO:0042742]; epithelial cell apoptotic process [GO:1904019]; flagellated sperm motility [GO:0030317]; Leydig cell differentiation [GO:0033327]; luteinizing hormone secretion [GO:0032275]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of gene expression [GO:0010629]; positive regulation of cytokine production [GO:0001819]; positive regulation of testosterone secretion [GO:2000845]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of proteasomal protein catabolic process [GO:0061136]; spermatid nucleus differentiation [GO:0007289] GO:0000139; GO:0001675; GO:0001819; GO:0003677; GO:0005634; GO:0005783; GO:0005794; GO:0005829; GO:0007289; GO:0010629; GO:0030317; GO:0030374; GO:0030521; GO:0032275; GO:0033327; GO:0042742; GO:0045944; GO:0050681; GO:0061136; GO:1904019; GO:1904036; GO:2000845 35537 XM_044310691.1 17 0 0 1 9 NA NA NA NA NA NA 35538 XM_044311597.1 85 0 9 12 24 NA NA NA NA NA NA 35539 XM_044322951.1 178 0 49 72 129 NA NA NA NA NA NA 35540 XM_029343454.2 0 0 0 44 37 NA NA NA NA NA NA 35541 XM_029335904.2 2049 2270 1826 1650 1265 Q9CQK1 4.26e-22 Zinc finger HIT domain-containing protein 3 (Thyroid hormone receptor interactor 3) (Thyroid receptor-interacting protein 3) (TR-interacting protein 3) (TRIP-3) Mus musculus (Mouse) box C/D snoRNP assembly [GO:0000492]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; snoRNA localization [GO:0048254] GO:0000463; GO:0000492; GO:0005634; GO:0005737; GO:0046872; GO:0048254; GO:0070761 35542 XM_044310106.1 0 29 0 0 0 NA NA NA NA NA NA 35543 XM_044324568.1 0 57 0 19 0 H1AFJ5 2.64e-39 Amiloride-sensitive sodium channel subunit alpha (Alpha-NaCH) (Epithelial Na(+) channel subunit alpha) (Alpha-ENaC) (Nonvoltage-gated sodium channel 1 subunit alpha) (SCNEA) Neoceratodus forsteri (Australian lungfish) (Ceratodus forsteri) sodium ion transmembrane transport [GO:0035725] GO:0001669; GO:0005737; GO:0015280; GO:0016324; GO:0031514; GO:0034706; GO:0035725 35544 XM_029328687.2 0 0 0 14 51 Q4KLT3 6.67e-135 Probable tRNA (uracil-O(2)-)-methyltransferase (EC 2.1.1.211) (Methyltransferase-like protein 19) Xenopus laevis (African clawed frog) NA GO:0005737; GO:0046872; GO:0052665 35545 XM_029333516.2 631 224 197 201 202 NA NA NA NA NA NA 35546 XM_044310468.1 212 37 33 115 156 NA NA NA NA NA NA 35547 XM_044328080.1 1591 1880 1078 2437 4739 Q5XIU9 1.1e-25 Membrane-associated progesterone receptor component 2 Rattus norvegicus (Rat) adipose tissue development [GO:0060612]; heme transport [GO:0015886] GO:0005496; GO:0005635; GO:0005783; GO:0012505; GO:0015232; GO:0015886; GO:0016020; GO:0020037; GO:0060612 35548 XR_006397589.1 18 4 9 7 30 NA NA NA NA NA NA 35549 XM_044311209.1 0 0 0 0 85 NA NA NA NA NA NA 35550 XM_029350494.2 21 0 18 5 27 NA NA NA NA NA NA 35551 XM_044328433.1 239 98 93 131 187 A6NHR9 0 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 (SMC hinge domain-containing protein 1) (EC 3.6.1.-) Homo sapiens (Human) chromosome organization [GO:0051276]; dosage compensation by inactivation of X chromosome [GO:0009048]; double-strand break repair [GO:0006302]; inactivation of X chromosome by heterochromatin formation [GO:0060820]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; nose development [GO:0043584]; positive regulation of DNA repair [GO:0045739]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034] GO:0001740; GO:0003677; GO:0005524; GO:0006302; GO:0009048; GO:0016887; GO:0035861; GO:0042803; GO:0043584; GO:0045739; GO:0051276; GO:0060820; GO:2000042; GO:2001034 35552 XM_044313942.1 0 4 5 0 19 B8VIU6 7.25e-64 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 35553 XM_044312081.1 6 52 51 51 59 NA NA NA NA NA NA 35554 XM_029348342.2 2080 2424 1403 4331 1525 NA NA NA NA NA NA 35555 XM_029329898.2 16 5 6 44 11 NA NA NA NA NA NA 35556 XM_029327176.2 65 106 22 69 79 NA NA NA NA NA NA 35557 XM_029347942.2 201 107 140 287 250 NA NA NA NA NA NA 35558 XM_044326941.1 255 230 93 278 121 Q6BZW3 8.14e-31 Protein BTN1 Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica) L-arginine transmembrane transport [GO:1903826]; lysine transport [GO:0015819]; regulation of intracellular pH [GO:0051453] GO:0000324; GO:0005773; GO:0005774; GO:0015819; GO:0022857; GO:0051453; GO:1903826 35559 XM_044321114.1 32 21 2 131 85 Q9H1A4 0 Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Mitotic checkpoint regulator) (Testis-specific gene 24 protein) Homo sapiens (Human) anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; metaphase/anaphase transition of mitotic cell cycle [GO:0007091]; protein K11-linked ubiquitination [GO:0070979]; regulation of meiotic cell cycle [GO:0051445]; regulation of mitotic cell cycle [GO:0007346] GO:0005654; GO:0005680; GO:0005829; GO:0007091; GO:0007346; GO:0031145; GO:0051301; GO:0051445; GO:0060090; GO:0070979 35560 XM_044320041.1 313 309 171 474 569 Q5U243 4.24e-138 CAP-Gly domain-containing linker protein 3 (Cytoplasmic linker protein 170-related 59 kDa protein) (CLIP-170-related 59 kDa protein) (CLIPR-59) Xenopus laevis (African clawed frog) NA GO:0005795 35561 XM_029332163.2 111 108 93 103 93 Q5YKK9 6.06e-21 Melanopsin (Opsin-4) Felis catus (Cat) (Felis silvestris catus) cellular response to light stimulus [GO:0071482]; detection of temperature stimulus involved in thermoception [GO:0050960]; G protein-coupled receptor signaling pathway [GO:0007186]; hyaloid vascular plexus regression [GO:1990384]; optokinetic behavior [GO:0007634]; phototransduction [GO:0007602]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511]; thermotaxis [GO:0043052]; visual perception [GO:0007601] GO:0005502; GO:0005886; GO:0007186; GO:0007601; GO:0007602; GO:0007634; GO:0008020; GO:0016020; GO:0030424; GO:0030425; GO:0042752; GO:0043052; GO:0043204; GO:0048511; GO:0050960; GO:0071482; GO:1990384; GO:1990913 35562 XM_044326679.1 91 19 83 84 70 NA NA NA NA NA NA 35563 XM_029349766.2 0 0 0 0 13 NA NA NA NA NA NA 35564 XM_029358334.2 4851 5538 4768 5616 3241 NA NA NA NA NA NA 35565 XM_044319680.1 112 31 81 14 0 NA NA NA NA NA NA 35566 XM_029342021.2 479 372 203 421 373 Q1JQD2 5.46e-156 Glutamate-rich WD repeat-containing protein 1 Bos taurus (Bovine) DNA replication [GO:0006260]; nucleosome assembly [GO:0006334]; nucleosome disassembly [GO:0006337]; ribosome biogenesis [GO:0042254] GO:0003682; GO:0003688; GO:0005634; GO:0005654; GO:0005694; GO:0005730; GO:0005829; GO:0006260; GO:0006334; GO:0006337; GO:0032991; GO:0042254; GO:0042393 35567 XR_006396149.1 58 172 16 35 31 P95896 2.26e-39 Amidase (EC 3.5.1.4) Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) NA GO:0004040; GO:0043864 35568 XR_006392906.1 41 2 25 5 151 NA NA NA NA NA NA 35569 XR_006394069.1 21 3 4 15 12 NA NA NA NA NA NA 35570 XM_044316474.1 0 0 0 2 8 NA NA NA NA NA NA 35571 XM_029358176.2 0 0 94 0 10 Q6REY9 1.51e-97 Rho GTPase-activating protein 20 (RA and RhoGAP domain-containing protein) (RARhoGAP) (Rho-type GTPase-activating protein 20) Rattus norvegicus (Rat) regulation of Rho protein signal transduction [GO:0035023]; signal transduction [GO:0007165] GO:0005096; GO:0007165; GO:0031267; GO:0035023 35572 XM_029323736.2 690 161 2618 247 2669 Q6PDK2 6.66e-178 Histone-lysine N-methyltransferase 2D (Lysine N-methyltransferase 2D) (EC 2.1.1.364) (ALL1-related protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 2) Mus musculus (Mouse) heterochromatin formation [GO:0031507]; histone H3-K4 dimethylation [GO:0044648]; histone H3-K4 monomethylation [GO:0097692]; histone H3-K4 trimethylation [GO:0080182]; in utero embryonic development [GO:0001701]; oocyte growth [GO:0001555]; oogenesis [GO:0048477]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression [GO:0010468]; response to estrogen [GO:0043627] GO:0000976; GO:0001228; GO:0001555; GO:0001701; GO:0003713; GO:0005654; GO:0008284; GO:0010468; GO:0031507; GO:0033148; GO:0035097; GO:0042393; GO:0042800; GO:0043627; GO:0044648; GO:0044666; GO:0045944; GO:0046872; GO:0048477; GO:0080182; GO:0097692; GO:0140945 35573 XM_029323736.2 690 161 2618 247 2669 Q6PDK2 7.11e-78 Histone-lysine N-methyltransferase 2D (Lysine N-methyltransferase 2D) (EC 2.1.1.364) (ALL1-related protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 2) Mus musculus (Mouse) heterochromatin formation [GO:0031507]; histone H3-K4 dimethylation [GO:0044648]; histone H3-K4 monomethylation [GO:0097692]; histone H3-K4 trimethylation [GO:0080182]; in utero embryonic development [GO:0001701]; oocyte growth [GO:0001555]; oogenesis [GO:0048477]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression [GO:0010468]; response to estrogen [GO:0043627] GO:0000976; GO:0001228; GO:0001555; GO:0001701; GO:0003713; GO:0005654; GO:0008284; GO:0010468; GO:0031507; GO:0033148; GO:0035097; GO:0042393; GO:0042800; GO:0043627; GO:0044648; GO:0044666; GO:0045944; GO:0046872; GO:0048477; GO:0080182; GO:0097692; GO:0140945 35574 XM_029323736.2 690 161 2618 247 2669 Q6PDK2 1.74e-66 Histone-lysine N-methyltransferase 2D (Lysine N-methyltransferase 2D) (EC 2.1.1.364) (ALL1-related protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 2) Mus musculus (Mouse) heterochromatin formation [GO:0031507]; histone H3-K4 dimethylation [GO:0044648]; histone H3-K4 monomethylation [GO:0097692]; histone H3-K4 trimethylation [GO:0080182]; in utero embryonic development [GO:0001701]; oocyte growth [GO:0001555]; oogenesis [GO:0048477]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression [GO:0010468]; response to estrogen [GO:0043627] GO:0000976; GO:0001228; GO:0001555; GO:0001701; GO:0003713; GO:0005654; GO:0008284; GO:0010468; GO:0031507; GO:0033148; GO:0035097; GO:0042393; GO:0042800; GO:0043627; GO:0044648; GO:0044666; GO:0045944; GO:0046872; GO:0048477; GO:0080182; GO:0097692; GO:0140945 35575 XM_029323736.2 690 161 2618 247 2669 Q6PDK2 2.75e-26 Histone-lysine N-methyltransferase 2D (Lysine N-methyltransferase 2D) (EC 2.1.1.364) (ALL1-related protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 2) Mus musculus (Mouse) heterochromatin formation [GO:0031507]; histone H3-K4 dimethylation [GO:0044648]; histone H3-K4 monomethylation [GO:0097692]; histone H3-K4 trimethylation [GO:0080182]; in utero embryonic development [GO:0001701]; oocyte growth [GO:0001555]; oogenesis [GO:0048477]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression [GO:0010468]; response to estrogen [GO:0043627] GO:0000976; GO:0001228; GO:0001555; GO:0001701; GO:0003713; GO:0005654; GO:0008284; GO:0010468; GO:0031507; GO:0033148; GO:0035097; GO:0042393; GO:0042800; GO:0043627; GO:0044648; GO:0044666; GO:0045944; GO:0046872; GO:0048477; GO:0080182; GO:0097692; GO:0140945 35576 XM_044327468.1 51 21 3 56 3 NA NA NA NA NA NA 35577 XM_029353737.2 0 0 11 10 0 NA NA NA NA NA NA 35578 XR_006395448.1 211 124 165 125 224 NA NA NA NA NA NA 35579 XM_029353112.2 65 0 0 0 10 P49582 2.44e-77 Neuronal acetylcholine receptor subunit alpha-7 Mus musculus (Mouse) acetylcholine receptor signaling pathway [GO:0095500]; associative learning [GO:0008306]; B cell activation [GO:0042113]; behavioral response to ethanol [GO:0048149]; behavioral response to nicotine [GO:0035095]; calcium ion transport [GO:0006816]; chemical synaptic transmission [GO:0007268]; dendrite arborization [GO:0140059]; dendritic spine organization [GO:0097061]; endocytosis [GO:0006897]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; generation of ovulation cycle rhythm [GO:0060112]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; learning or memory [GO:0007611]; membrane depolarization [GO:0051899]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; modulation of excitatory postsynaptic potential [GO:0098815]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of tumor necrosis factor production [GO:0032720]; nervous system process [GO:0050877]; neuronal action potential [GO:0019228]; ovulation cycle [GO:0042698]; positive regulation of acetylcholine biosynthetic process [GO:1905923]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of CoA-transferase activity [GO:1905920]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure [GO:0001988]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of amyloid fibril formation [GO:1905906]; regulation of inflammatory response [GO:0050727]; regulation of membrane potential [GO:0042391]; regulation of neuron death [GO:1901214]; regulation of nitric oxide metabolic process [GO:0080164]; regulation of norepinephrine secretion [GO:0014061]; regulation of response to drug [GO:2001023]; regulation of synapse structural plasticity [GO:0051823]; regulation of synaptic transmission, cholinergic [GO:0032222]; regulation of synaptic transmission, dopaminergic [GO:0032225]; response to acetylcholine [GO:1905144]; response to amyloid-beta [GO:1904645]; response to cold [GO:0009409]; response to ethanol [GO:0045471]; response to food [GO:0032094]; response to nicotine [GO:0035094]; sensory processing [GO:0050893]; signal transduction [GO:0007165]; synapse organization [GO:0050808]; synaptic transmission, cholinergic [GO:0007271]; T cell activation [GO:0042110] GO:0001540; GO:0001933; GO:0001934; GO:0001988; GO:0005216; GO:0005231; GO:0005737; GO:0005886; GO:0005892; GO:0006811; GO:0006816; GO:0006897; GO:0007165; GO:0007268; GO:0007271; GO:0007611; GO:0007613; GO:0008179; GO:0008306; GO:0009409; GO:0009897; GO:0010628; GO:0014061; GO:0014069; GO:0015464; GO:0015643; GO:0016020; GO:0016324; GO:0017081; GO:0019228; GO:0019901; GO:0022848; GO:0030317; GO:0030424; GO:0030425; GO:0030426; GO:0030594; GO:0030673; GO:0032094; GO:0032222; GO:0032225; GO:0032279; GO:0032691; GO:0032715; GO:0032720; GO:0033138; GO:0034220; GO:0035094; GO:0035095; GO:0042110; GO:0042113; GO:0042166; GO:0042391; GO:0042698; GO:0042734; GO:0042803; GO:0043005; GO:0043025; GO:0043197; GO:0043198; GO:0044853; GO:0045121; GO:0045202; GO:0045211; GO:0045471; GO:0048149; GO:0050727; GO:0050728; GO:0050804; GO:0050808; GO:0050877; GO:0050893; GO:0051117; GO:0051247; GO:0051649; GO:0051823; GO:0051899; GO:0060112; GO:0070373; GO:0070374; GO:0080164; GO:0095500; GO:0097061; GO:0097110; GO:0098690; GO:0098793; GO:0098815; GO:0098897; GO:0098981; GO:0099171; GO:0099634; GO:0140059; GO:1900273; GO:1901214; GO:1902004; GO:1904315; GO:1904645; GO:1905144; GO:1905906; GO:1905920; GO:1905923; GO:2000463; GO:2001023 35580 XR_006393180.1 129 318 402 501 637 NA NA NA NA NA NA 35581 XM_044318841.1 491 316 328 326 327 Q7YS61 5.5e-103 tRNA (cytosine(38)-C(5))-methyltransferase (EC 2.1.1.204) (DNA (cytosine-5)-methyltransferase-like protein 2) (Dnmt2) Bos taurus (Bovine) tRNA C5-cytosine methylation [GO:0002946]; tRNA methylation [GO:0030488]; tRNA stabilization [GO:0036416] GO:0002946; GO:0003723; GO:0005634; GO:0005737; GO:0016428; GO:0030488; GO:0036416 35582 XM_029342288.2 0 0 3 6 5 NA NA NA NA NA NA 35583 XM_029356098.2 36 63 59 77 131 NA NA NA NA NA NA 35584 XM_044310528.1 4 1 6 1 6 NA NA NA NA NA NA 35585 XM_044327465.1 30 52 20 31 13 Q8BY79 3.05e-34 Solute carrier family 35 member G1 (Transmembrane protein 20) Mus musculus (Mouse) calcium ion export across plasma membrane [GO:1990034]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0005789; GO:0005886; GO:0016020; GO:0051480; GO:1990034 35586 XM_029331994.2 39 4 8 17 2 NA NA NA NA NA NA 35587 XM_029343417.2 1689 1077 1000 1524 1595 Q6ZUT9 0 DENN domain-containing protein 5B (Rab6IP1-like protein) Homo sapiens (Human) positive regulation of triglyceride transport [GO:1905885] GO:0005085; GO:0005829; GO:0016020; GO:0031267; GO:1905885 35588 XM_029343417.2 1689 1077 1000 1524 1595 Q6ZUT9 3.39e-124 DENN domain-containing protein 5B (Rab6IP1-like protein) Homo sapiens (Human) positive regulation of triglyceride transport [GO:1905885] GO:0005085; GO:0005829; GO:0016020; GO:0031267; GO:1905885 35589 XM_044326472.1 1386 1646 1038 1423 929 Q5IS99 3.13e-50 Caspase-3 (CASP-3) (EC 3.4.22.56) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12] Saimiri boliviensis boliviensis (Bolivian squirrel monkey) cellular response to staurosporine [GO:0072734]; erythrocyte differentiation [GO:0030218]; intracellular signal transduction [GO:0035556]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of amyloid-beta formation [GO:1902004]; proteolysis [GO:0006508]; regulation of protein stability [GO:0031647] GO:0004175; GO:0005634; GO:0005829; GO:0006508; GO:0030218; GO:0031647; GO:0035556; GO:0048011; GO:0072734; GO:0097153; GO:0097199; GO:0097200; GO:1902004 35590 XM_044321407.1 6 26 9 14 29 Q9D6L8 1.57e-84 Peptidyl-prolyl cis-trans isomerase-like 3 (PPIase) (EC 5.2.1.8) (CYP10L) (Cyclophilin-like protein PPIL3) (Rotamase PPIL3) Mus musculus (Mouse) mRNA processing [GO:0006397]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; RNA splicing [GO:0008380] GO:0000413; GO:0003755; GO:0006397; GO:0006457; GO:0008380; GO:0071013 35591 XR_003825351.2 1 31 1 11 12 Q7LG56 2.09e-33 Ribonucleoside-diphosphate reductase subunit M2 B (EC 1.17.4.1) (TP53-inducible ribonucleotide reductase M2 B) (p53-inducible ribonucleotide reductase small subunit 2-like protein) (p53R2) Homo sapiens (Human) 2'-deoxyribonucleotide biosynthetic process [GO:0009265]; deoxyribonucleoside triphosphate metabolic process [GO:0009200]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA repair [GO:0006281]; DNA synthesis involved in DNA repair [GO:0000731]; kidney development [GO:0001822]; mitochondrial DNA replication [GO:0006264]; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902254]; positive regulation of G0 to G1 transition [GO:0070318]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; renal system process [GO:0003014]; response to amine [GO:0014075]; response to oxidative stress [GO:0006979]; ribonucleoside diphosphate metabolic process [GO:0009185] GO:0000731; GO:0001822; GO:0003014; GO:0004748; GO:0005654; GO:0005739; GO:0005829; GO:0005971; GO:0006264; GO:0006281; GO:0006979; GO:0009185; GO:0009200; GO:0009263; GO:0009265; GO:0010971; GO:0014075; GO:0042802; GO:0046872; GO:0070318; GO:1902254 35592 XM_029346550.2 18 29 58 70 25 P41384 2.76e-39 Cyclin-dependent kinases regulatory subunit (SUC1 homolog) Patella vulgata (Common limpet) cell cycle [GO:0007049]; cell division [GO:0051301] GO:0007049; GO:0016538; GO:0051301 35593 XM_029336090.2 52 0 0 0 0 NA NA NA NA NA NA 35594 XM_044317596.1 7 19 5 7 16 NA NA NA NA NA NA 35595 XM_044321444.1 12 0 9 0 0 NA NA NA NA NA NA 35596 XM_044320533.1 130 57 143 121 116 Q7RTR2 1.13e-41 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 35597 XM_044320533.1 130 57 143 121 116 Q7RTR2 6.67e-41 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 35598 XM_044320533.1 130 57 143 121 116 Q7RTR2 9.64e-29 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 35599 XR_006391309.1 43 10 7 17 34 NA NA NA NA NA NA 35600 XM_044326975.1 93 51 48 32 98 Q9JHH6 1.89e-84 Carboxypeptidase B2 (EC 3.4.17.20) (Carboxypeptidase R) (CPR) (Carboxypeptidase U) (CPU) (Thrombin-activable fibrinolysis inhibitor) (TAFI) Mus musculus (Mouse) blood coagulation [GO:0007596]; cellular response to glucose stimulus [GO:0071333]; fibrinolysis [GO:0042730]; liver regeneration [GO:0097421]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of hepatocyte proliferation [GO:2000346]; negative regulation of plasminogen activation [GO:0010757]; positive regulation of extracellular matrix constituent secretion [GO:0003331]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to xenobiotic stimulus [GO:0009410] GO:0003331; GO:0004180; GO:0004181; GO:0005615; GO:0006508; GO:0007596; GO:0008270; GO:0009408; GO:0009410; GO:0010757; GO:0030163; GO:0042730; GO:0051918; GO:0071333; GO:0097421; GO:2000346 35601 XM_029337028.2 36 16 24 9 32 Q8HYZ1 2.38e-98 Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2) Mustela putorius furo (European domestic ferret) (Mustela furo) cardiac muscle cell action potential [GO:0086001]; cellular response to hypoxia [GO:0071456]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005250; GO:0005886; GO:0005901; GO:0008076; GO:0030315; GO:0032809; GO:0034765; GO:0042383; GO:0043197; GO:0043204; GO:0044853; GO:0045211; GO:0046872; GO:0051260; GO:0070161; GO:0071456; GO:0071805; GO:0086001 35602 XM_044308226.1 31 4 20 44 27 B3EWZ6 3.62e-47 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 35603 XM_044308226.1 31 4 20 44 27 B3EWZ6 5.33e-45 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 35604 XM_044308226.1 31 4 20 44 27 B3EWZ6 1.5e-44 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 35605 XM_044308226.1 31 4 20 44 27 B3EWZ6 3.42e-43 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 35606 XM_044308226.1 31 4 20 44 27 B3EWZ6 2.28e-40 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 35607 XM_044308226.1 31 4 20 44 27 B3EWZ6 1.6e-38 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 35608 XM_044308226.1 31 4 20 44 27 B3EWZ6 6.82e-38 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 35609 XM_044308226.1 31 4 20 44 27 B3EWZ6 4.11e-28 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 35610 XM_044308226.1 31 4 20 44 27 B3EWZ6 3.12e-27 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 35611 XM_044308226.1 31 4 20 44 27 B3EWZ6 1.81e-26 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 35612 XM_044308226.1 31 4 20 44 27 B3EWZ6 2.61e-24 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 35613 XM_044308226.1 31 4 20 44 27 B3EWZ6 9.48e-24 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 35614 XM_044308226.1 31 4 20 44 27 B3EWZ6 4.23e-23 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 35615 XM_044308226.1 31 4 20 44 27 B3EWZ6 9.12e-23 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 35616 XM_044308226.1 31 4 20 44 27 B3EWZ6 1.09e-22 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 35617 XM_044308226.1 31 4 20 44 27 B3EWZ6 1.26e-22 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 35618 XM_044308226.1 31 4 20 44 27 B3EWZ6 1.84e-22 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 35619 XM_044308226.1 31 4 20 44 27 B3EWZ6 1.27e-21 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 35620 XM_044308226.1 31 4 20 44 27 B3EWZ6 3.86e-21 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 35621 XM_044308226.1 31 4 20 44 27 B3EWZ6 7.38e-21 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 35622 XM_044308226.1 31 4 20 44 27 B3EWZ6 8.46e-21 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 35623 XM_044308226.1 31 4 20 44 27 B3EWZ6 8.68e-21 MAM and LDL-receptor class A domain-containing protein 2 (Skeletal organic matrix MAM and LDL-receptor 2) (SOM MAM and LDL-receptor 2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 35624 XM_044321268.1 0 0 16 0 245 NA NA NA NA NA NA 35625 XM_044316782.1 655 408 470 701 1364 NA NA NA NA NA NA 35626 XM_044310868.1 26 7 3 72 16 Q3UQ28 3.03e-31 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 35627 XM_044310868.1 26 7 3 72 16 Q3UQ28 8.4e-28 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 35628 XM_029355414.2 93 158 104 78 285 NA NA NA NA NA NA 35629 XM_029328723.2 29 0 114 69 141 O88845 1.63e-83 A-kinase anchor protein 10, mitochondrial (AKAP-10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2) (Protein kinase A-anchoring protein 10) (PRKA10) Mus musculus (Mouse) protein localization [GO:0008104] GO:0005739; GO:0005829; GO:0005886; GO:0008104; GO:0032991; GO:0051018 35630 XM_044326140.1 0 0 9 22 0 Q09575 3.88e-63 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 35631 XM_029342111.2 233 111 90 61 314 Q6GLC9 9.26e-104 Fragile X messenger ribonucleoprotein 1 homolog (XtFmrp) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) brain development [GO:0007420]; branching morphogenesis of a nerve [GO:0048755]; cartilage development [GO:0051216]; cognition [GO:0050890]; DNA repair [GO:0006281]; forebrain-midbrain boundary formation [GO:0021905]; glutamate receptor signaling pathway [GO:0007215]; mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; negative regulation of cytoplasmic translation [GO:2000766]; negative regulation of gene expression [GO:0010629]; negative regulation of long-term synaptic depression [GO:1900453]; negative regulation of synaptic vesicle exocytosis [GO:2000301]; negative regulation of translation [GO:0017148]; negative regulation of translational initiation [GO:0045947]; negative regulation of voltage-gated calcium channel activity [GO:1901386]; neural crest cell fate specification [GO:0014036]; neuron projection morphogenesis [GO:0048812]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; positive regulation of mRNA binding [GO:1902416]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of receptor internalization [GO:0002092]; positive regulation of translation [GO:0045727]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of dendritic spine development [GO:0060998]; regulation of filopodium assembly [GO:0051489]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of mRNA modification [GO:0090365]; regulation of mRNA stability [GO:0043488]; regulation of neuronal action potential [GO:0098908]; regulation of neurotransmitter secretion [GO:0046928]; RNA splicing [GO:0008380]; skeletal muscle organ development [GO:0060538] GO:0000381; GO:0000775; GO:0002092; GO:0002151; GO:0003682; GO:0003723; GO:0003729; GO:0003730; GO:0005634; GO:0005654; GO:0005694; GO:0005730; GO:0005737; GO:0005844; GO:0006281; GO:0006397; GO:0007215; GO:0007420; GO:0008017; GO:0008266; GO:0008380; GO:0010369; GO:0010494; GO:0010629; GO:0014036; GO:0014069; GO:0017148; GO:0019897; GO:0021905; GO:0030371; GO:0030424; GO:0030425; GO:0030426; GO:0032433; GO:0033592; GO:0034046; GO:0035064; GO:0035197; GO:0035198; GO:0035613; GO:0036464; GO:0042734; GO:0042803; GO:0042995; GO:0043005; GO:0043197; GO:0043204; GO:0043488; GO:0043679; GO:0045202; GO:0045211; GO:0045727; GO:0045947; GO:0046928; GO:0046982; GO:0048027; GO:0048471; GO:0048755; GO:0048812; GO:0050890; GO:0051028; GO:0051216; GO:0051489; GO:0051491; GO:0060538; GO:0060964; GO:0060998; GO:0060999; GO:0070840; GO:0071598; GO:0090365; GO:0097386; GO:0098793; GO:0098794; GO:0098908; GO:1900453; GO:1901386; GO:1901800; GO:1902416; GO:1902737; GO:1990812; GO:1990825; GO:1990904; GO:2000301; GO:2000637; GO:2000766 35632 XR_006397360.1 65 147 56 73 82 NA NA NA NA NA NA 35633 XR_003824097.2 3675 5745 2311 2077 3270 NA NA NA NA NA NA 35634 XM_029355768.2 801 954 686 696 367 NA NA NA NA NA NA 35635 XR_006397941.1 10 25 9 22 13 NA NA NA NA NA NA 35636 XM_044328821.1 1 0 9 0 2 NA NA NA NA NA NA 35637 XM_029350058.2 133 69 110 315 374 P12111 2.77e-51 Collagen alpha-3(VI) chain Homo sapiens (Human) cell adhesion [GO:0007155]; muscle organ development [GO:0007517]; negative regulation of peptidase activity [GO:0010466] GO:0004867; GO:0005576; GO:0005589; GO:0005615; GO:0005788; GO:0007155; GO:0007517; GO:0010466; GO:0030020; GO:0031012; GO:0042383; GO:0062023; GO:0070062; GO:1903561 35638 XM_029350058.2 133 69 110 315 374 P12111 9.95e-50 Collagen alpha-3(VI) chain Homo sapiens (Human) cell adhesion [GO:0007155]; muscle organ development [GO:0007517]; negative regulation of peptidase activity [GO:0010466] GO:0004867; GO:0005576; GO:0005589; GO:0005615; GO:0005788; GO:0007155; GO:0007517; GO:0010466; GO:0030020; GO:0031012; GO:0042383; GO:0062023; GO:0070062; GO:1903561 35639 XM_029350058.2 133 69 110 315 374 P12111 1.86e-41 Collagen alpha-3(VI) chain Homo sapiens (Human) cell adhesion [GO:0007155]; muscle organ development [GO:0007517]; negative regulation of peptidase activity [GO:0010466] GO:0004867; GO:0005576; GO:0005589; GO:0005615; GO:0005788; GO:0007155; GO:0007517; GO:0010466; GO:0030020; GO:0031012; GO:0042383; GO:0062023; GO:0070062; GO:1903561 35640 XM_029350058.2 133 69 110 315 374 P12111 1.31e-31 Collagen alpha-3(VI) chain Homo sapiens (Human) cell adhesion [GO:0007155]; muscle organ development [GO:0007517]; negative regulation of peptidase activity [GO:0010466] GO:0004867; GO:0005576; GO:0005589; GO:0005615; GO:0005788; GO:0007155; GO:0007517; GO:0010466; GO:0030020; GO:0031012; GO:0042383; GO:0062023; GO:0070062; GO:1903561 35641 XM_029350058.2 133 69 110 315 374 P12111 4.3e-31 Collagen alpha-3(VI) chain Homo sapiens (Human) cell adhesion [GO:0007155]; muscle organ development [GO:0007517]; negative regulation of peptidase activity [GO:0010466] GO:0004867; GO:0005576; GO:0005589; GO:0005615; GO:0005788; GO:0007155; GO:0007517; GO:0010466; GO:0030020; GO:0031012; GO:0042383; GO:0062023; GO:0070062; GO:1903561 35642 XM_029350058.2 133 69 110 315 374 P12111 1.41e-28 Collagen alpha-3(VI) chain Homo sapiens (Human) cell adhesion [GO:0007155]; muscle organ development [GO:0007517]; negative regulation of peptidase activity [GO:0010466] GO:0004867; GO:0005576; GO:0005589; GO:0005615; GO:0005788; GO:0007155; GO:0007517; GO:0010466; GO:0030020; GO:0031012; GO:0042383; GO:0062023; GO:0070062; GO:1903561 35643 XM_029350058.2 133 69 110 315 374 P12111 2.09e-28 Collagen alpha-3(VI) chain Homo sapiens (Human) cell adhesion [GO:0007155]; muscle organ development [GO:0007517]; negative regulation of peptidase activity [GO:0010466] GO:0004867; GO:0005576; GO:0005589; GO:0005615; GO:0005788; GO:0007155; GO:0007517; GO:0010466; GO:0030020; GO:0031012; GO:0042383; GO:0062023; GO:0070062; GO:1903561 35644 XM_029355754.2 21 6 0 0 53 P24044 1.8e-47 Calmodulin Plasmodium falciparum NA GO:0005509; GO:0005737; GO:0020007 35645 XM_044319924.1 399 682 189 1059 603 Q5XJN2 3.8e-51 Gamma-interferon-inducible lysosomal thiol reductase (EC 1.8.-.-) (Gamma-interferon-inducible protein IP-30) Danio rerio (Zebrafish) (Brachydanio rerio) immune system process [GO:0002376] GO:0002376; GO:0005576; GO:0005764; GO:0016491; GO:0016667; GO:0016671; GO:0047134 35646 XR_006394921.1 71 108 53 88 105 NA NA NA NA NA NA 35647 XM_029339607.2 705 161 36 252 0 P30997 4.21e-46 Catenin alpha-2 (Alpha N-catenin) (Neural alpha-catenin) Gallus gallus (Chicken) axonogenesis [GO:0007409]; brain morphogenesis [GO:0048854]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; dendrite morphogenesis [GO:0048813]; epithelial cell differentiation [GO:0030855]; neural crest cell migration [GO:0001755]; protein localization [GO:0008104]; regulation of synapse structural plasticity [GO:0051823]; trigeminal ganglion formation [GO:0061561] GO:0001755; GO:0005198; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0005912; GO:0007409; GO:0008013; GO:0008104; GO:0015629; GO:0016342; GO:0016477; GO:0030424; GO:0030855; GO:0045296; GO:0048813; GO:0048854; GO:0051015; GO:0051823; GO:0061561; GO:0098609 35648 XM_029354051.2 7 8 6 4 21 NA NA NA NA NA NA 35649 XM_044309162.1 72 0 202 7 92 NA NA NA NA NA NA 35650 XR_006394523.1 45 30 30 29 117 NA NA NA NA NA NA 35651 XR_006395090.1 7 0 10 3 0 NA NA NA NA NA NA 35652 XM_029333011.2 697 371 199 416 398 NA NA NA NA NA NA 35653 XM_044315079.1 6 0 0 0 0 NA NA NA NA NA NA 35654 XM_044314665.1 208 178 73 140 352 Q5F371 1.58e-41 Protein strawberry notch homolog 1 Gallus gallus (Chicken) regulation of DNA-templated transcription [GO:0006355]; regulation of response to stimulus [GO:0048583] GO:0005634; GO:0006355; GO:0031490; GO:0042393; GO:0048583 35655 XM_044328636.1 72 52 28 67 0 NA NA NA NA NA NA 35656 XM_029337030.2 108 45 12 0 0 Q8HYZ1 3.23e-100 Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2) Mustela putorius furo (European domestic ferret) (Mustela furo) cardiac muscle cell action potential [GO:0086001]; cellular response to hypoxia [GO:0071456]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005250; GO:0005886; GO:0005901; GO:0008076; GO:0030315; GO:0032809; GO:0034765; GO:0042383; GO:0043197; GO:0043204; GO:0044853; GO:0045211; GO:0046872; GO:0051260; GO:0070161; GO:0071456; GO:0071805; GO:0086001 35657 XM_029331128.2 581 429 359 442 845 Q6PFM0 1.29e-156 Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 (EC 1.14.11.-) (Histone arginine demethylase JMJD6) (JmjC domain-containing protein 6) (Jumonji domain-containing protein 6) (Lysyl-hydroxylase JMJD6) (Peptide-lysine 5-dioxygenase JMJD6) (Phosphatidylserine receptor) (Protein PTDSR) (zfpsr) Danio rerio (Zebrafish) (Brachydanio rerio) cell differentiation [GO:0030154]; chromatin organization [GO:0006325]; mRNA processing [GO:0006397]; peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine [GO:0018395]; phagocytosis [GO:0006909]; protein homooligomerization [GO:0051260]; regulation of mRNA splicing, via spliceosome [GO:0048024]; RNA splicing [GO:0008380]; sprouting angiogenesis [GO:0002040] GO:0002040; GO:0003727; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0006325; GO:0006397; GO:0006909; GO:0008380; GO:0018395; GO:0030154; GO:0032452; GO:0033746; GO:0033749; GO:0046872; GO:0048024; GO:0051260; GO:0070815; GO:0106140 35658 XM_044312516.1 102 60 15 79 17 A6H730 1.4e-69 Prostatic acid phosphatase (EC 3.1.3.2) (Protein tyrosine phosphatase ACP3) (EC 3.1.3.48) Bos taurus (Bovine) adenosine metabolic process [GO:0046085]; dephosphorylation [GO:0016311]; lipid metabolic process [GO:0006629]; lysosome organization [GO:0007040]; positive regulation of adenosine receptor signaling pathway [GO:0060168]; regulation of sensory perception of pain [GO:0051930]; thiamine metabolic process [GO:0006772] GO:0003993; GO:0004725; GO:0005615; GO:0005764; GO:0005886; GO:0006629; GO:0006772; GO:0007040; GO:0008253; GO:0012506; GO:0016311; GO:0016791; GO:0042131; GO:0046085; GO:0051930; GO:0052642; GO:0060168 35659 XM_029335898.2 111 95 100 123 160 E7F7V7 9.72e-26 Galanin receptor 2b Danio rerio (Zebrafish) (Brachydanio rerio) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; neuropeptide signaling pathway [GO:0007218] GO:0004966; GO:0005886; GO:0007188; GO:0007218; GO:0008528 35660 XM_029338250.2 3327 2631 2062 3371 3336 Q8IS64 0 Endothelin-converting enzyme homolog (ECE) (EC 3.4.24.-) Locusta migratoria (Migratory locust) proteolysis [GO:0006508] GO:0004175; GO:0004222; GO:0005886; GO:0006508; GO:0008270 35661 XM_044314415.1 378 33 0 1 32 NA NA NA NA NA NA 35662 XR_006392321.1 0 12 0 0 119 NA NA NA NA NA NA 35663 XM_044315665.1 117 22 7 115 101 NA NA NA NA NA NA 35664 XM_029341819.2 6483 4207 2385 4599 3027 Q9Y2I6 1.34e-33 Ninein-like protein Homo sapiens (Human) microtubule anchoring at centrosome [GO:0034454] GO:0005509; GO:0005813; GO:0005829; GO:0005874; GO:0015630; GO:0034454; GO:0045171 35665 XM_029349051.2 4 2 10 1 0 NA NA NA NA NA NA 35666 XM_044307088.1 46 9 28 0 0 NA NA NA NA NA NA 35667 XM_044324300.1 4444 3578 3148 7509 6207 NA NA NA NA NA NA 35668 XM_044313247.1 64 0 0 0 0 NA NA NA NA NA NA 35669 XM_044324165.1 0 2 3 0 8 NA NA NA NA NA NA 35670 XM_029352499.2 3711 1987 2011 3257 2501 NA NA NA NA NA NA 35671 XM_029324482.2 67 320 126 168 1 Q9N294 3.9e-24 Beta-1,3-galactosyltransferase 5 (Beta-1,3-GalTase 5) (Beta3Gal-T5) (Beta3GalT5) (b3Gal-T5) (EC 2.4.1.-) (Beta-3-Gx-T5) (UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 5) (UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 5) Pan paniscus (Pygmy chimpanzee) (Bonobo) lipid metabolic process [GO:0006629]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0006629; GO:0016758 35672 XM_029353427.2 1 204 60 330 0 NA NA NA NA NA NA 35673 XR_006393841.1 2 2 0 14 8 NA NA NA NA NA NA 35674 XM_029341128.2 1115 1117 709 1319 800 NA NA NA NA NA NA 35675 XM_044327879.1 39 0 73 15 161 NA NA NA NA NA NA 35676 XM_044319945.1 139 41 66 63 50 Q9NTJ5 0 Phosphatidylinositol-3-phosphatase SAC1 (EC 3.1.3.64) (Phosphatidylinositol-4-phosphate phosphatase) (Suppressor of actin mutations 1-like protein) Homo sapiens (Human) phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856] GO:0000139; GO:0004438; GO:0005783; GO:0005789; GO:0005794; GO:0006661; GO:0016791; GO:0034596; GO:0043812; GO:0046856; GO:0140268 35677 XM_044319153.1 4 0 0 59 0 NA NA NA NA NA NA 35678 XM_029355926.2 86 133 101 154 142 B5XF11 1.36e-117 Lysine-specific demethylase 8 (EC 1.14.11.27) (JmjC domain-containing protein 5) (Jumonji domain-containing protein 5) Salmo salar (Atlantic salmon) chromatin organization [GO:0006325]; circadian regulation of gene expression [GO:0032922]; G2/M transition of mitotic cell cycle [GO:0000086]; positive regulation of DNA-templated transcription [GO:0045893] GO:0000086; GO:0003682; GO:0005634; GO:0006325; GO:0032922; GO:0045893; GO:0046872; GO:0051864; GO:0140680 35679 XM_029333162.2 6255 6022 2163 3754 2949 Q5RFN0 4.25e-47 ADP-ribosylation factor-like protein 15 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003924; GO:0005525 35680 XM_029353228.2 0 0 15 0 0 NA NA NA NA NA NA 35681 XR_006392852.1 2 0 0 14 8 NA NA NA NA NA NA 35682 XM_044320044.1 2 0 9 7 0 NA NA NA NA NA NA 35683 XM_029347918.2 1014 569 561 882 1149 Q96NL6 5.57e-78 Sodium channel and clathrin linker 1 (Sodium channel-associated protein 1) Homo sapiens (Human) cilium assembly [GO:0060271]; clustering of voltage-gated sodium channels [GO:0045162] GO:0005813; GO:0005814; GO:0005829; GO:0008022; GO:0017080; GO:0030276; GO:0045162; GO:0060271; GO:0071439; GO:0097539 35684 XM_044311913.1 2 10 0 1 4 NA NA NA NA NA NA 35685 XM_029350873.2 0 0 1 0 59 Q6VFT6 3.64e-53 Forkhead box protein L2 Sus scrofa (Pig) anatomical structure morphogenesis [GO:0009653]; apoptotic DNA fragmentation [GO:0006309]; cell differentiation [GO:0030154]; embryonic eye morphogenesis [GO:0048048]; extraocular skeletal muscle development [GO:0002074]; female somatic sex determination [GO:0019101]; granulosa cell differentiation [GO:0060014]; ovarian follicle development [GO:0001541]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0001541; GO:0002074; GO:0003677; GO:0003700; GO:0005634; GO:0006309; GO:0006357; GO:0009653; GO:0019101; GO:0030154; GO:0043028; GO:0043065; GO:0043280; GO:0045893; GO:0045944; GO:0048048; GO:0060014 35686 XM_029339809.2 200 1312 911 1313 918 NA NA NA NA NA NA 35687 XM_044318238.1 542 406 325 524 326 F4JTS8 3.03e-148 Protein NO VEIN (Protein EMBRYO DEFECTIVE 2597) Arabidopsis thaliana (Mouse-ear cress) auxin polar transport [GO:0009926]; cell fate specification [GO:0001708]; embryo development ending in seed dormancy [GO:0009793]; leaf vascular tissue pattern formation [GO:0010305]; root development [GO:0048364]; stem cell population maintenance [GO:0019827] GO:0001708; GO:0005634; GO:0009793; GO:0009926; GO:0010305; GO:0019827; GO:0048364 35688 XR_006396369.1 113 10 54 7 153 NA NA NA NA NA NA 35689 XR_003827330.2 0 6 0 0 0 NA NA NA NA NA NA 35690 XM_044320773.1 28 0 3 0 2 B3EWZ5 2.04e-24 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 35691 XM_044320773.1 28 0 3 0 2 B3EWZ5 3.5e-23 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 35692 XM_044320773.1 28 0 3 0 2 B3EWZ5 1.45e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 35693 XM_029355918.2 14 0 0 4 0 Q8JGM4 7.53e-117 Sulfhydryl oxidase 1 (EC 1.8.3.2) (Quiescin Q6) Gallus gallus (Chicken) protein folding [GO:0006457] GO:0000139; GO:0003756; GO:0005615; GO:0006457; GO:0016971 35694 XM_029332013.2 249 188 243 479 449 NA NA NA NA NA NA 35695 XM_044327672.1 147 0 0 0 0 Q5FWL3 8.83e-141 E3 ubiquitin-protein ligase NRDP1 (EC 2.3.2.27) (RING finger protein 41) (RING-type E3 ubiquitin transferase NRDP1) Xenopus laevis (African clawed frog) extrinsic apoptotic signaling pathway [GO:0097191]; protein polyubiquitination [GO:0000209] GO:0000209; GO:0004842; GO:0046872; GO:0061630; GO:0097191 35696 XM_044307082.1 459 115 96 268 536 P26446 0 Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 1) (ARTD1) (DNA ADP-ribosyltransferase PARP1) (EC 2.4.2.-) (NAD(+) ADP-ribosyltransferase 1) (ADPRT 1) (Poly[ADP-ribose] synthase 1) (Protein poly-ADP-ribosyltransferase PARP1) (EC 2.4.2.-) Gallus gallus (Chicken) ATP generation from poly-ADP-D-ribose [GO:1990966]; DNA ADP-ribosylation [GO:0030592]; DNA repair [GO:0006281]; innate immune response [GO:0045087]; negative regulation of innate immune response [GO:0045824]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; protein auto-ADP-ribosylation [GO:0070213]; protein poly-ADP-ribosylation [GO:0070212]; replication fork reversal [GO:0071932] GO:0000122; GO:0000785; GO:0003684; GO:0003950; GO:0005730; GO:0005829; GO:0006281; GO:0008270; GO:0016779; GO:0030592; GO:0031491; GO:0035861; GO:0042803; GO:0043596; GO:0045087; GO:0045824; GO:0051287; GO:0070212; GO:0070213; GO:0071932; GO:0140805; GO:0140806; GO:0140807; GO:0140808; GO:0140815; GO:1905168; GO:1990404; GO:1990966 35697 XR_003826114.2 3718 3751 2758 2861 2321 NA NA NA NA NA NA 35698 XM_044316023.1 110 35 134 112 171 NA NA NA NA NA NA 35699 XM_029323632.2 611 380 243 489 524 NA NA NA NA NA NA 35700 XM_029342917.2 2186 736 1002 919 1172 Q3B8K3 2.19e-23 28S ribosomal protein S24-B, mitochondrial (MRP-S24-B) (S24mt-B) Xenopus laevis (African clawed frog) mitochondrial translation [GO:0032543] GO:0003735; GO:0005763; GO:0032543 35701 XR_006393896.1 41 2 25 5 151 NA NA NA NA NA NA 35702 XM_044314801.1 16 0 8 5 15 NA NA NA NA NA NA 35703 XM_029349331.2 40 3 37 61 226 Q6DFC2 1.59e-167 Coiled-coil domain-containing protein 77 Xenopus laevis (African clawed frog) NA NA 35704 XM_029353815.2 4084 4421 2572 2002 3433 Q6U841 0 Sodium-driven chloride bicarbonate exchanger (Solute carrier family 4 member 10) Homo sapiens (Human) bicarbonate transport [GO:0015701]; brain morphogenesis [GO:0048854]; chloride transport [GO:0006821]; ion homeostasis [GO:0050801]; locomotory exploration behavior [GO:0035641]; multicellular organism growth [GO:0035264]; post-embryonic development [GO:0009791]; proton transmembrane transport [GO:1902600]; pyramidal neuron development [GO:0021860]; regulation of intracellular pH [GO:0051453]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; response to light stimulus [GO:0009416]; transmembrane transport [GO:0055085]; visual perception [GO:0007601] GO:0005452; GO:0005886; GO:0006821; GO:0007601; GO:0008510; GO:0009416; GO:0009791; GO:0015701; GO:0016020; GO:0016323; GO:0016324; GO:0021860; GO:0022857; GO:0030425; GO:0035264; GO:0035641; GO:0036477; GO:0043025; GO:0043204; GO:0043679; GO:0045202; GO:0048172; GO:0048854; GO:0050801; GO:0051453; GO:0055085; GO:0097440; GO:0097441; GO:0097442; GO:0098794; GO:0140892; GO:1902600 35705 XM_044319225.1 4036 1145 372 3041 873 NA NA NA NA NA NA 35706 XM_029330784.2 22 4 10 10 14 NA NA NA NA NA NA 35707 XM_044323316.1 125 76 115 115 56 Q149M9 9.33e-80 NACHT domain- and WD repeat-containing protein 1 Homo sapiens (Human) negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of gene expression [GO:0010628] GO:0005524; GO:0005730; GO:0005829; GO:0010628; GO:0032088 35708 XR_006394661.1 221 208 176 228 403 NA NA NA NA NA NA 35709 XM_044311104.1 16 5 0 0 0 NA NA NA NA NA NA 35710 XM_044313625.1 9 20 32 36 60 NA NA NA NA NA NA 35711 XM_044308984.1 5 0 30 0 8 NA NA NA NA NA NA 35712 XM_029343617.2 6 1 70 0 111 NA NA NA NA NA NA 35713 XM_044323942.1 21 75 20 16 12 Q9CXI3 1.04e-121 DBH-like monooxygenase protein 1 (EC 1.14.17.-) (DBH-related protein) (Monooxygenase X) Mus musculus (Mouse) dopamine catabolic process [GO:0042420]; norepinephrine biosynthetic process [GO:0042421]; octopamine biosynthetic process [GO:0006589] GO:0004500; GO:0005507; GO:0005615; GO:0005789; GO:0006589; GO:0030667; GO:0042420; GO:0042421 35714 XR_006391491.1 912 7226 23 31 59 NA NA NA NA NA NA 35715 XR_006393076.1 41 2 25 5 151 NA NA NA NA NA NA 35716 XM_029326470.2 0 9 0 18 0 NA NA NA NA NA NA 35717 XM_044306948.1 2 0 3 11 62 NA NA NA NA NA NA 35718 XM_029348824.2 34 10 10 7 3 NA NA NA NA NA NA 35719 XM_029341204.2 55 30 0 2 38 NA NA NA NA NA NA 35720 XM_044314485.1 595 575 456 1132 610 Q5TCS8 0 Adenylate kinase 9 (AK 9) (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase domain-containing protein 1) (Adenylate kinase domain-containing protein 2) Homo sapiens (Human) AMP phosphorylation [GO:0006756]; ATP generation from ADP [GO:0006757]; CDP phosphorylation [GO:0061508]; CMP phosphorylation [GO:0061566]; dADP phosphorylation [GO:0006174]; dAMP phosphorylation [GO:0061565]; dCDP phosphorylation [GO:0061570]; dCMP phosphorylation [GO:0061567]; dGDP phosphorylation [GO:0006186]; GDP phosphorylation [GO:0061568]; TDP phosphorylation [GO:0061571]; UDP phosphorylation [GO:0061569] GO:0004017; GO:0004550; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005829; GO:0006174; GO:0006186; GO:0006756; GO:0006757; GO:0031965; GO:0050145; GO:0061508; GO:0061565; GO:0061566; GO:0061567; GO:0061568; GO:0061569; GO:0061570; GO:0061571 35721 XM_044314485.1 595 575 456 1132 610 Q5TCS8 8.94e-93 Adenylate kinase 9 (AK 9) (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase domain-containing protein 1) (Adenylate kinase domain-containing protein 2) Homo sapiens (Human) AMP phosphorylation [GO:0006756]; ATP generation from ADP [GO:0006757]; CDP phosphorylation [GO:0061508]; CMP phosphorylation [GO:0061566]; dADP phosphorylation [GO:0006174]; dAMP phosphorylation [GO:0061565]; dCDP phosphorylation [GO:0061570]; dCMP phosphorylation [GO:0061567]; dGDP phosphorylation [GO:0006186]; GDP phosphorylation [GO:0061568]; TDP phosphorylation [GO:0061571]; UDP phosphorylation [GO:0061569] GO:0004017; GO:0004550; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005829; GO:0006174; GO:0006186; GO:0006756; GO:0006757; GO:0031965; GO:0050145; GO:0061508; GO:0061565; GO:0061566; GO:0061567; GO:0061568; GO:0061569; GO:0061570; GO:0061571 35722 XM_044314485.1 595 575 456 1132 610 Q5TCS8 1.38e-31 Adenylate kinase 9 (AK 9) (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase domain-containing protein 1) (Adenylate kinase domain-containing protein 2) Homo sapiens (Human) AMP phosphorylation [GO:0006756]; ATP generation from ADP [GO:0006757]; CDP phosphorylation [GO:0061508]; CMP phosphorylation [GO:0061566]; dADP phosphorylation [GO:0006174]; dAMP phosphorylation [GO:0061565]; dCDP phosphorylation [GO:0061570]; dCMP phosphorylation [GO:0061567]; dGDP phosphorylation [GO:0006186]; GDP phosphorylation [GO:0061568]; TDP phosphorylation [GO:0061571]; UDP phosphorylation [GO:0061569] GO:0004017; GO:0004550; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005829; GO:0006174; GO:0006186; GO:0006756; GO:0006757; GO:0031965; GO:0050145; GO:0061508; GO:0061565; GO:0061566; GO:0061567; GO:0061568; GO:0061569; GO:0061570; GO:0061571 35723 XM_044315052.1 38 26 62 23 100 NA NA NA NA NA NA 35724 XM_029344647.2 10 1 3 1 6 A6QNK1 1.47e-46 Galactosylceramide sulfotransferase (GalCer sulfotransferase) (EC 2.8.2.11) (3'-phosphoadenosine-5'-phosphosulfate:GalCer sulfotransferase) (3'-phosphoadenylylsulfate:galactosylceramide 3'-sulfotransferase) (Cerebroside sulfotransferase) Bos taurus (Bovine) galactosylceramide biosynthetic process [GO:0006682]; galactosylceramide metabolic process [GO:0006681]; glycerolipid metabolic process [GO:0046486]; myelination [GO:0042552]; sphingolipid metabolic process [GO:0006665] GO:0000139; GO:0001733; GO:0006665; GO:0006681; GO:0006682; GO:0008146; GO:0042552; GO:0046486; GO:0050694 35725 XM_029327548.2 367 238 298 266 289 NA NA NA NA NA NA 35726 XM_044315977.1 40 12 0 0 2 NA NA NA NA NA NA 35727 XM_029352379.2 494 457 605 937 784 Q3TIT8 1.24e-155 Sugar phosphate exchanger 3 (Solute carrier family 37 member 3) Mus musculus (Mouse) carbohydrate transport [GO:0008643] GO:0005789; GO:0008643; GO:0022857 35728 XM_029323448.2 1531 1026 700 1276 1250 P29374 3.45e-79 AT-rich interactive domain-containing protein 4A (ARID domain-containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1) Homo sapiens (Human) erythrocyte development [GO:0048821]; establishment of Sertoli cell barrier [GO:0097368]; histone H3-K4 trimethylation [GO:0080182]; histone H3-K9 trimethylation [GO:0036124]; histone H4-K20 trimethylation [GO:0034773]; negative regulation of cell migration [GO:0030336]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of stem cell population maintenance [GO:1902455]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression by genomic imprinting [GO:0006349]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]; transcription by RNA polymerase II [GO:0006366] GO:0000122; GO:0000976; GO:0003677; GO:0005634; GO:0005654; GO:0005829; GO:0005886; GO:0006349; GO:0006357; GO:0006366; GO:0007283; GO:0016580; GO:0017053; GO:0030336; GO:0030512; GO:0034773; GO:0036124; GO:0045892; GO:0045944; GO:0048821; GO:0080182; GO:0097368; GO:1902455; GO:1902459 35729 XM_044315004.1 64 36 90 32 248 NA NA NA NA NA NA 35730 XM_029333807.2 87 171 109 46 146 NA NA NA NA NA NA 35731 XM_044327580.1 48 5 0 0 15 NA NA NA NA NA NA 35732 XR_006396752.1 0 0 0 20 10 NA NA NA NA NA NA 35733 XR_003826579.2 250 2 86 411 171 NA NA NA NA NA NA 35734 XM_044321278.1 568 298 203 431 454 B6ELU0 1.97e-40 tRNA-cytidine(32) 2-sulfurtransferase (EC 2.8.1.-) (Two-thiocytidine biosynthesis protein A) (tRNA 2-thiocytidine biosynthesis protein TtcA) Aliivibrio salmonicida (strain LFI1238) (Vibrio salmonicida (strain LFI1238)) tRNA thio-modification [GO:0034227] GO:0000049; GO:0000287; GO:0005524; GO:0005737; GO:0016783; GO:0034227; GO:0051539 35735 XM_044316371.1 0 0 1 7 2 NA NA NA NA NA NA 35736 XR_006397321.1 80 20 72 85 86 Q32P85 6.74e-23 Dynein light chain roadblock-type 2 (Dynein light chain 2B, cytoplasmic) Bos taurus (Bovine) microtubule-based movement [GO:0007018] GO:0005737; GO:0005813; GO:0005868; GO:0005874; GO:0007018; GO:0045505 35737 XM_044323135.1 6 57 0 3 0 NA NA NA NA NA NA 35738 XM_029356147.2 107 242 27 36 0 NA NA NA NA NA NA 35739 XM_044307365.1 25 12 9 17 52 NA NA NA NA NA NA 35740 XM_029341540.2 1450 1892 1168 2082 1814 Q5FWK3 2.75e-112 Rho GTPase-activating protein 1 (Rho-type GTPase-activating protein 1) Mus musculus (Mouse) endosomal transport [GO:0016197]; negative regulation of endocytic recycling [GO:2001136]; regulation of GTPase activity [GO:0043087]; small GTPase mediated signal transduction [GO:0007264]; transferrin transport [GO:0033572] GO:0001726; GO:0005096; GO:0005737; GO:0005886; GO:0007264; GO:0010008; GO:0016197; GO:0017124; GO:0031252; GO:0031267; GO:0033572; GO:0043087; GO:0048471; GO:0097443; GO:2001136 35741 XM_044314095.1 0 0 1 0 7 NA NA NA NA NA NA 35742 XM_044317954.1 0 0 0 0 7 Q9SZJ2 1.84e-36 Glycine-rich domain-containing protein 2 (AtGRDP2) Arabidopsis thaliana (Mouse-ear cress) auxin-activated signaling pathway [GO:0009734]; cellular response to osmotic stress [GO:0071470]; regulation of auxin mediated signaling pathway [GO:0010928]; regulation of photoperiodism, flowering [GO:2000028] GO:0009734; GO:0010928; GO:0071470; GO:2000028 35743 XM_044317452.1 13 0 0 0 0 Q9VJJ7 3.64e-51 Transient receptor potential-gamma protein (TRPgamma) (Transient receptor potential cation channel gamma) Drosophila melanogaster (Fruit fly) adult walking behavior [GO:0007628]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cation transport [GO:0006812]; detection of light stimulus involved in visual perception [GO:0050908]; neuromuscular process controlling posture [GO:0050884]; regulation of cytosolic calcium ion concentration [GO:0051480]; response to light stimulus [GO:0009416] GO:0005261; GO:0005262; GO:0005886; GO:0006812; GO:0006816; GO:0007628; GO:0008381; GO:0009416; GO:0015279; GO:0016028; GO:0034703; GO:0043025; GO:0050884; GO:0050908; GO:0051480; GO:0070588; GO:0070679; GO:1990635 35744 XM_044313288.1 0 70 5 6 12 NA NA NA NA NA NA 35745 XM_044323552.1 54 0 51 115 23 E1BD59 1.51e-21 E3 ubiquitin-protein ligase TRIM56 (EC 2.3.2.27) (Tripartite motif-containing protein 56) Bos taurus (Bovine) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of interferon-beta production [GO:0032728]; protein K63-linked ubiquitination [GO:0070534]; response to type I interferon [GO:0034340] GO:0000785; GO:0004842; GO:0005654; GO:0005737; GO:0008270; GO:0032728; GO:0034340; GO:0045087; GO:0045893; GO:0051607; GO:0061630; GO:0070534 35746 XM_029333719.2 1636 1868 1005 2896 1187 O00180 3.39e-44 Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1) (Potassium channel K2P1) (Potassium channel KCNO1) Homo sapiens (Human) potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of resting membrane potential [GO:0060075]; response to nicotine [GO:0035094]; sodium ion transmembrane transport [GO:0035725]; stabilization of membrane potential [GO:0030322] GO:0005242; GO:0005267; GO:0005272; GO:0005886; GO:0006813; GO:0008076; GO:0016020; GO:0016324; GO:0022841; GO:0030322; GO:0030425; GO:0031526; GO:0034705; GO:0035094; GO:0035725; GO:0042802; GO:0043204; GO:0043231; GO:0055037; GO:0060075; GO:0071805; GO:0097060; GO:1902937 35747 XM_029338772.2 16 0 0 1 0 NA NA NA NA NA NA 35748 XM_044320293.1 373 201 154 198 528 NA NA NA NA NA NA 35749 XR_006395888.1 8 12 0 3 16 NA NA NA NA NA NA 35750 XM_044325124.1 105 53 0 197 158 B3EX02 9e-124 MAM and fibronectin type III domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 35751 XM_044325124.1 105 53 0 197 158 B3EX02 4.46e-122 MAM and fibronectin type III domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 35752 XM_044325124.1 105 53 0 197 158 B3EX02 4.28e-112 MAM and fibronectin type III domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 35753 XM_044325124.1 105 53 0 197 158 B3EX02 6.92e-29 MAM and fibronectin type III domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 35754 XM_044325124.1 105 53 0 197 158 B3EX02 1.61e-23 MAM and fibronectin type III domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 35755 XM_029351634.2 586 165 305 513 649 NA NA NA NA NA NA 35756 XM_029339665.2 6 11 14 14 43 NA NA NA NA NA NA 35757 XM_029343693.2 694 836 1046 785 730 Q9UFN0 7.23e-30 Protein NipSnap homolog 3A (NipSnap3A) (Protein NipSnap homolog 4) (NipSnap4) (Target for Salmonella secreted protein C) (TassC) Homo sapiens (Human) NA GO:0005634; GO:0005739; GO:0005829 35758 XR_003826111.2 466 101 61 277 206 NA NA NA NA NA NA 35759 XM_044327748.1 82 78 45 2 44 Q05609 1.56e-25 Serine/threonine-protein kinase CTR1 (EC 2.7.11.1) (Protein CONSTITUTIVE TRIPLE RESPONSE1) Arabidopsis thaliana (Mouse-ear cress) ethylene-activated signaling pathway [GO:0009873]; gibberellin biosynthetic process [GO:0009686]; negative regulation of ethylene-activated signaling pathway [GO:0010105]; protein autophosphorylation [GO:0046777]; regulation of post-embryonic root development [GO:2000069]; regulation of stem cell division [GO:2000035]; regulation of timing of transition from vegetative to reproductive phase [GO:0048510]; response to ethylene [GO:0009723]; response to fructose [GO:0009750]; response to hypoxia [GO:0001666]; response to sucrose [GO:0009744]; sugar mediated signaling pathway [GO:0010182] GO:0001666; GO:0004674; GO:0004712; GO:0005524; GO:0005789; GO:0009686; GO:0009723; GO:0009744; GO:0009750; GO:0009873; GO:0010105; GO:0010182; GO:0046777; GO:0048510; GO:0106310; GO:2000035; GO:2000069 35760 XM_029336103.2 18850 16936 10002 20888 19402 P53448 0 Fructose-bisphosphate aldolase C (EC 4.1.2.13) (Brain-type aldolase) Carassius auratus (Goldfish) fructose 1,6-bisphosphate metabolic process [GO:0030388]; glycolytic process [GO:0006096] GO:0004332; GO:0006096; GO:0030388 35761 XM_029332143.2 1201 625 856 1096 1010 H2QII6 1.48e-78 E3 SUMO-protein ligase RanBP2 (EC 2.3.2.-) (358 kDa nucleoporin) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (Ran-binding protein 2) (RanBP2) Pan troglodytes (Chimpanzee) mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein sumoylation [GO:0016925] GO:0000413; GO:0003723; GO:0003755; GO:0005635; GO:0005642; GO:0005643; GO:0005737; GO:0006457; GO:0006607; GO:0016740; GO:0016925; GO:0031965; GO:0046872; GO:0051028 35762 XM_029332143.2 1201 625 856 1096 1010 H2QII6 3.95e-52 E3 SUMO-protein ligase RanBP2 (EC 2.3.2.-) (358 kDa nucleoporin) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (Ran-binding protein 2) (RanBP2) Pan troglodytes (Chimpanzee) mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein sumoylation [GO:0016925] GO:0000413; GO:0003723; GO:0003755; GO:0005635; GO:0005642; GO:0005643; GO:0005737; GO:0006457; GO:0006607; GO:0016740; GO:0016925; GO:0031965; GO:0046872; GO:0051028 35763 XM_029332143.2 1201 625 856 1096 1010 H2QII6 5.21e-52 E3 SUMO-protein ligase RanBP2 (EC 2.3.2.-) (358 kDa nucleoporin) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (Ran-binding protein 2) (RanBP2) Pan troglodytes (Chimpanzee) mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein sumoylation [GO:0016925] GO:0000413; GO:0003723; GO:0003755; GO:0005635; GO:0005642; GO:0005643; GO:0005737; GO:0006457; GO:0006607; GO:0016740; GO:0016925; GO:0031965; GO:0046872; GO:0051028 35764 XM_029332143.2 1201 625 856 1096 1010 H2QII6 4.51e-46 E3 SUMO-protein ligase RanBP2 (EC 2.3.2.-) (358 kDa nucleoporin) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (Ran-binding protein 2) (RanBP2) Pan troglodytes (Chimpanzee) mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein sumoylation [GO:0016925] GO:0000413; GO:0003723; GO:0003755; GO:0005635; GO:0005642; GO:0005643; GO:0005737; GO:0006457; GO:0006607; GO:0016740; GO:0016925; GO:0031965; GO:0046872; GO:0051028 35765 XM_029332143.2 1201 625 856 1096 1010 H2QII6 6.21e-46 E3 SUMO-protein ligase RanBP2 (EC 2.3.2.-) (358 kDa nucleoporin) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (Ran-binding protein 2) (RanBP2) Pan troglodytes (Chimpanzee) mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein sumoylation [GO:0016925] GO:0000413; GO:0003723; GO:0003755; GO:0005635; GO:0005642; GO:0005643; GO:0005737; GO:0006457; GO:0006607; GO:0016740; GO:0016925; GO:0031965; GO:0046872; GO:0051028 35766 XM_029332143.2 1201 625 856 1096 1010 H2QII6 1.1e-40 E3 SUMO-protein ligase RanBP2 (EC 2.3.2.-) (358 kDa nucleoporin) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (Ran-binding protein 2) (RanBP2) Pan troglodytes (Chimpanzee) mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein sumoylation [GO:0016925] GO:0000413; GO:0003723; GO:0003755; GO:0005635; GO:0005642; GO:0005643; GO:0005737; GO:0006457; GO:0006607; GO:0016740; GO:0016925; GO:0031965; GO:0046872; GO:0051028 35767 XM_029332143.2 1201 625 856 1096 1010 H2QII6 1.71e-40 E3 SUMO-protein ligase RanBP2 (EC 2.3.2.-) (358 kDa nucleoporin) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (Ran-binding protein 2) (RanBP2) Pan troglodytes (Chimpanzee) mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein sumoylation [GO:0016925] GO:0000413; GO:0003723; GO:0003755; GO:0005635; GO:0005642; GO:0005643; GO:0005737; GO:0006457; GO:0006607; GO:0016740; GO:0016925; GO:0031965; GO:0046872; GO:0051028 35768 XM_029332143.2 1201 625 856 1096 1010 H2QII6 7.64e-40 E3 SUMO-protein ligase RanBP2 (EC 2.3.2.-) (358 kDa nucleoporin) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (Ran-binding protein 2) (RanBP2) Pan troglodytes (Chimpanzee) mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein sumoylation [GO:0016925] GO:0000413; GO:0003723; GO:0003755; GO:0005635; GO:0005642; GO:0005643; GO:0005737; GO:0006457; GO:0006607; GO:0016740; GO:0016925; GO:0031965; GO:0046872; GO:0051028 35769 XM_029332143.2 1201 625 856 1096 1010 H2QII6 8.3e-40 E3 SUMO-protein ligase RanBP2 (EC 2.3.2.-) (358 kDa nucleoporin) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (Ran-binding protein 2) (RanBP2) Pan troglodytes (Chimpanzee) mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein sumoylation [GO:0016925] GO:0000413; GO:0003723; GO:0003755; GO:0005635; GO:0005642; GO:0005643; GO:0005737; GO:0006457; GO:0006607; GO:0016740; GO:0016925; GO:0031965; GO:0046872; GO:0051028 35770 XM_029332143.2 1201 625 856 1096 1010 H2QII6 1.98e-34 E3 SUMO-protein ligase RanBP2 (EC 2.3.2.-) (358 kDa nucleoporin) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (Ran-binding protein 2) (RanBP2) Pan troglodytes (Chimpanzee) mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein sumoylation [GO:0016925] GO:0000413; GO:0003723; GO:0003755; GO:0005635; GO:0005642; GO:0005643; GO:0005737; GO:0006457; GO:0006607; GO:0016740; GO:0016925; GO:0031965; GO:0046872; GO:0051028 35771 XM_029332143.2 1201 625 856 1096 1010 H2QII6 4.99e-34 E3 SUMO-protein ligase RanBP2 (EC 2.3.2.-) (358 kDa nucleoporin) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (Ran-binding protein 2) (RanBP2) Pan troglodytes (Chimpanzee) mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein sumoylation [GO:0016925] GO:0000413; GO:0003723; GO:0003755; GO:0005635; GO:0005642; GO:0005643; GO:0005737; GO:0006457; GO:0006607; GO:0016740; GO:0016925; GO:0031965; GO:0046872; GO:0051028 35772 XM_029332143.2 1201 625 856 1096 1010 H2QII6 1.04e-33 E3 SUMO-protein ligase RanBP2 (EC 2.3.2.-) (358 kDa nucleoporin) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (Ran-binding protein 2) (RanBP2) Pan troglodytes (Chimpanzee) mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein sumoylation [GO:0016925] GO:0000413; GO:0003723; GO:0003755; GO:0005635; GO:0005642; GO:0005643; GO:0005737; GO:0006457; GO:0006607; GO:0016740; GO:0016925; GO:0031965; GO:0046872; GO:0051028 35773 XM_029332143.2 1201 625 856 1096 1010 H2QII6 3.9e-33 E3 SUMO-protein ligase RanBP2 (EC 2.3.2.-) (358 kDa nucleoporin) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (Ran-binding protein 2) (RanBP2) Pan troglodytes (Chimpanzee) mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein sumoylation [GO:0016925] GO:0000413; GO:0003723; GO:0003755; GO:0005635; GO:0005642; GO:0005643; GO:0005737; GO:0006457; GO:0006607; GO:0016740; GO:0016925; GO:0031965; GO:0046872; GO:0051028 35774 XM_029332143.2 1201 625 856 1096 1010 H2QII6 5.34e-32 E3 SUMO-protein ligase RanBP2 (EC 2.3.2.-) (358 kDa nucleoporin) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (Ran-binding protein 2) (RanBP2) Pan troglodytes (Chimpanzee) mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein sumoylation [GO:0016925] GO:0000413; GO:0003723; GO:0003755; GO:0005635; GO:0005642; GO:0005643; GO:0005737; GO:0006457; GO:0006607; GO:0016740; GO:0016925; GO:0031965; GO:0046872; GO:0051028 35775 XM_029332143.2 1201 625 856 1096 1010 H2QII6 2.81e-31 E3 SUMO-protein ligase RanBP2 (EC 2.3.2.-) (358 kDa nucleoporin) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (Ran-binding protein 2) (RanBP2) Pan troglodytes (Chimpanzee) mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein sumoylation [GO:0016925] GO:0000413; GO:0003723; GO:0003755; GO:0005635; GO:0005642; GO:0005643; GO:0005737; GO:0006457; GO:0006607; GO:0016740; GO:0016925; GO:0031965; GO:0046872; GO:0051028 35776 XM_029332143.2 1201 625 856 1096 1010 H2QII6 1.01e-28 E3 SUMO-protein ligase RanBP2 (EC 2.3.2.-) (358 kDa nucleoporin) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (Ran-binding protein 2) (RanBP2) Pan troglodytes (Chimpanzee) mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein sumoylation [GO:0016925] GO:0000413; GO:0003723; GO:0003755; GO:0005635; GO:0005642; GO:0005643; GO:0005737; GO:0006457; GO:0006607; GO:0016740; GO:0016925; GO:0031965; GO:0046872; GO:0051028 35777 XM_029332143.2 1201 625 856 1096 1010 H2QII6 3.2e-28 E3 SUMO-protein ligase RanBP2 (EC 2.3.2.-) (358 kDa nucleoporin) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (Ran-binding protein 2) (RanBP2) Pan troglodytes (Chimpanzee) mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein sumoylation [GO:0016925] GO:0000413; GO:0003723; GO:0003755; GO:0005635; GO:0005642; GO:0005643; GO:0005737; GO:0006457; GO:0006607; GO:0016740; GO:0016925; GO:0031965; GO:0046872; GO:0051028 35778 XM_029332143.2 1201 625 856 1096 1010 H2QII6 3.62e-26 E3 SUMO-protein ligase RanBP2 (EC 2.3.2.-) (358 kDa nucleoporin) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (Ran-binding protein 2) (RanBP2) Pan troglodytes (Chimpanzee) mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein sumoylation [GO:0016925] GO:0000413; GO:0003723; GO:0003755; GO:0005635; GO:0005642; GO:0005643; GO:0005737; GO:0006457; GO:0006607; GO:0016740; GO:0016925; GO:0031965; GO:0046872; GO:0051028 35779 XM_029332143.2 1201 625 856 1096 1010 H2QII6 6.2e-26 E3 SUMO-protein ligase RanBP2 (EC 2.3.2.-) (358 kDa nucleoporin) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (Ran-binding protein 2) (RanBP2) Pan troglodytes (Chimpanzee) mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein sumoylation [GO:0016925] GO:0000413; GO:0003723; GO:0003755; GO:0005635; GO:0005642; GO:0005643; GO:0005737; GO:0006457; GO:0006607; GO:0016740; GO:0016925; GO:0031965; GO:0046872; GO:0051028 35780 XM_029332143.2 1201 625 856 1096 1010 H2QII6 1.41e-22 E3 SUMO-protein ligase RanBP2 (EC 2.3.2.-) (358 kDa nucleoporin) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (Ran-binding protein 2) (RanBP2) Pan troglodytes (Chimpanzee) mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein sumoylation [GO:0016925] GO:0000413; GO:0003723; GO:0003755; GO:0005635; GO:0005642; GO:0005643; GO:0005737; GO:0006457; GO:0006607; GO:0016740; GO:0016925; GO:0031965; GO:0046872; GO:0051028 35781 XM_029332143.2 1201 625 856 1096 1010 H2QII6 1.62e-21 E3 SUMO-protein ligase RanBP2 (EC 2.3.2.-) (358 kDa nucleoporin) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (Ran-binding protein 2) (RanBP2) Pan troglodytes (Chimpanzee) mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein sumoylation [GO:0016925] GO:0000413; GO:0003723; GO:0003755; GO:0005635; GO:0005642; GO:0005643; GO:0005737; GO:0006457; GO:0006607; GO:0016740; GO:0016925; GO:0031965; GO:0046872; GO:0051028 35782 XR_006391608.1 530 11 23 516 452 NA NA NA NA NA NA 35783 XM_044316600.1 0 0 0 0 31 NA NA NA NA NA NA 35784 XM_029348159.2 3639 3384 1395 2308 2574 Q9D1Q6 1.37e-127 Endoplasmic reticulum resident protein 44 (ER protein 44) (ERp44) (Thioredoxin domain-containing protein 4) Mus musculus (Mouse) glycoprotein metabolic process [GO:0009100]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976]; response to unfolded protein [GO:0006986] GO:0003756; GO:0005788; GO:0005789; GO:0005793; GO:0006457; GO:0006986; GO:0009100; GO:0009986; GO:0034976 35785 XM_029333381.2 0 0 0 0 43 Q99614 4.8e-47 Tetratricopeptide repeat protein 1 (TPR repeat protein 1) Homo sapiens (Human) protein folding [GO:0006457] GO:0005778; GO:0005829; GO:0006457; GO:0051082 35786 XM_029351518.2 0 856 326 58 42 Q05BQ1 2.65e-48 Protein turtle homolog A (Dendrite arborization and synapse maturation protein 1) (Immunoglobulin superfamily member 9A) (IgSF9A) Mus musculus (Mouse) cell-cell adhesion [GO:0098609]; dendrite development [GO:0016358]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; regulation of synapse organization [GO:0050807] GO:0005886; GO:0007156; GO:0016358; GO:0030424; GO:0030425; GO:0050807; GO:0060077; GO:0098609; GO:0098632 35787 XM_029356792.2 466 5 3 559 3 P00767 7.83e-48 Chymotrypsinogen B (EC 3.4.21.1) [Cleaved into: Chymotrypsin B chain A; Chymotrypsin B chain B; Chymotrypsin B chain C] Bos taurus (Bovine) digestion [GO:0007586]; proteolysis [GO:0006508] GO:0004252; GO:0005615; GO:0006508; GO:0007586 35788 XM_029349535.2 42 0 49 0 41 NA NA NA NA NA NA 35789 XM_044308323.1 272 112 31 69 92 Q9NUV9 1.68e-21 GTPase IMAP family member 4 (Immunity-associated nucleotide 1 protein) (IAN-1) (hIAN1) (Immunity-associated protein 4) Homo sapiens (Human) NA GO:0005525; GO:0005829; GO:0043231 35790 XM_029323782.2 1856 1460 1171 1448 1294 Q99JW2 4.13e-173 Aminoacylase-1 (ACY-1) (EC 3.5.1.14) (N-acyl-L-amino-acid amidohydrolase) Mus musculus (Mouse) amino acid metabolic process [GO:0006520] GO:0004046; GO:0005737; GO:0006520; GO:0042802; GO:0046872; GO:0070062 35791 XM_044322382.1 411 177 422 175 636 Q5BKR2 1.16e-110 Sodium/hydrogen exchanger 9B2 (NHA-oc) (Na(+)/H(+) exchanger NHA2) (Na(+)/H(+) exchanger-like domain-containing protein 2) (NHE domain-containing protein 2) (Soditlum/hydrogen exchanger-like domain-containing protein 2) (Solute carrier family 9 subfamily B member 2) Mus musculus (Mouse) clathrin-dependent endocytosis [GO:0072583]; flagellated sperm motility [GO:0030317]; positive regulation of osteoclast development [GO:2001206]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; sodium ion transport [GO:0006814] GO:0005886; GO:0006814; GO:0010008; GO:0010348; GO:0015385; GO:0016323; GO:0030317; GO:0030672; GO:0031966; GO:0042802; GO:0061178; GO:0072583; GO:0097228; GO:2001206 35792 XM_044327665.1 91 27 0 76 159 NA NA NA NA NA NA 35793 XM_029353009.2 0 0 0 332 284 NA NA NA NA NA NA 35794 XM_029346165.2 11433 11675 10321 9864 9558 NA NA NA NA NA NA 35795 XM_029351072.2 988 1617 393 307 547 NA NA NA NA NA NA 35796 XM_044318553.1 1031 1246 262 255 379 Q96DM1 1.27e-42 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 35797 XM_029348064.2 342 143 0 294 33 NA NA NA NA NA NA 35798 XM_044318186.1 0 0 0 0 38 NA NA NA NA NA NA 35799 XM_029331070.2 339 182 139 305 174 NA NA NA NA NA NA 35800 XM_044326673.1 28 0 32 0 0 NA NA NA NA NA NA 35801 XM_044317192.1 467 167 420 241 2007 Q5DU56 2.29e-38 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 35802 XM_044317192.1 467 167 420 241 2007 Q5DU56 2.04e-36 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 35803 XM_044317192.1 467 167 420 241 2007 Q5DU56 3.42e-30 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 35804 XM_044317192.1 467 167 420 241 2007 Q5DU56 1.05e-27 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 35805 XM_044317192.1 467 167 420 241 2007 Q5DU56 1.31e-26 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 35806 XM_044325398.1 516 327 136 137 38 Q91W90 1.33e-96 Thioredoxin domain-containing protein 5 (EC 1.8.4.-) (EC 5.3.4.1) (Endoplasmic reticulum resident protein 46) (ER protein 46) (ERp46) (Plasma cell-specific thioredoxin-related protein) (PC-TRP) (Thioredoxin-like protein p46) Mus musculus (Mouse) protein folding [GO:0006457] GO:0003756; GO:0005783; GO:0005788; GO:0006457; GO:0015035 35807 XM_044325398.1 516 327 136 137 38 Q91W90 2.16e-52 Thioredoxin domain-containing protein 5 (EC 1.8.4.-) (EC 5.3.4.1) (Endoplasmic reticulum resident protein 46) (ER protein 46) (ERp46) (Plasma cell-specific thioredoxin-related protein) (PC-TRP) (Thioredoxin-like protein p46) Mus musculus (Mouse) protein folding [GO:0006457] GO:0003756; GO:0005783; GO:0005788; GO:0006457; GO:0015035 35808 XM_044314872.1 0 2 0 35 0 NA NA NA NA NA NA 35809 XM_029324383.2 6 2 0 0 3 NA NA NA NA NA NA 35810 XM_044326244.1 14 13 0 2 5 NA NA NA NA NA NA 35811 XM_044323944.1 107 142 60 88 56 Q9CXI3 1.86e-119 DBH-like monooxygenase protein 1 (EC 1.14.17.-) (DBH-related protein) (Monooxygenase X) Mus musculus (Mouse) dopamine catabolic process [GO:0042420]; norepinephrine biosynthetic process [GO:0042421]; octopamine biosynthetic process [GO:0006589] GO:0004500; GO:0005507; GO:0005615; GO:0005789; GO:0006589; GO:0030667; GO:0042420; GO:0042421 35812 XM_029338075.2 986 146 442 651 318 Q75V66 0 Anoctamin-5 (Gnathodiaphyseal dysplasia 1 protein) (Transmembrane protein 16E) Homo sapiens (Human) chloride transmembrane transport [GO:1902476]; chloride transport [GO:0006821]; ion transmembrane transport [GO:0034220]; transmembrane transport [GO:0055085] GO:0005229; GO:0005254; GO:0005789; GO:0005886; GO:0006821; GO:0031982; GO:0034220; GO:0046983; GO:0055085; GO:1902476 35813 XM_029348559.2 1645 1024 504 1079 895 Q9Z139 2.26e-133 Inactive tyrosine-protein kinase transmembrane receptor ROR1 (mROR1) (Neurotrophic tyrosine kinase, receptor-related 1) Mus musculus (Mouse) astrocyte development [GO:0014002]; inner ear development [GO:0048839]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of kinase activity [GO:0033674]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; sensory perception of sound [GO:0007605] GO:0001725; GO:0004714; GO:0005524; GO:0005737; GO:0005886; GO:0007605; GO:0009986; GO:0010976; GO:0014002; GO:0014068; GO:0017147; GO:0033674; GO:0042813; GO:0043123; GO:0043235; GO:0043679; GO:0048839; GO:0051092 35814 XM_044323729.1 4 0 0 1 7 NA NA NA NA NA NA 35815 XM_044308628.1 20 0 15 0 0 NA NA NA NA NA NA 35816 XM_029338474.2 1161 1068 176 820 153 NA NA NA NA NA NA 35817 XM_044307939.1 8 0 0 0 0 NA NA NA NA NA NA 35818 XM_044321292.1 23 0 3 51 44 A6QLD2 2.68e-52 Olfactomedin-like protein 2B Bos taurus (Bovine) extracellular matrix organization [GO:0030198]; signal transduction [GO:0007165] GO:0005615; GO:0007165; GO:0030198; GO:0031012; GO:0042802; GO:0050840 35819 XM_044322886.1 14 0 19 53 13 B3EWY9 1.41e-47 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 35820 XM_044322886.1 14 0 19 53 13 B3EWY9 4.71e-36 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 35821 XM_029330057.2 101 6775 3121 374 113 NA NA NA NA NA NA 35822 XM_044319120.1 148 170 101 240 2 NA NA NA NA NA NA 35823 XM_029349445.2 6 1 9 6 20 NA NA NA NA NA NA 35824 XM_044323888.1 0 184 16 36 249 NA NA NA NA NA NA 35825 XM_044327178.1 115 56 28 83 132 NA NA NA NA NA NA 35826 XM_029347664.2 195 129 145 163 192 NA NA NA NA NA NA 35827 XM_029336331.2 5393 2630 2664 3853 3874 Q5ZLA6 0 Unconventional myosin-Ic (Myosin I beta) (MMI-beta) (MMIb) Gallus gallus (Chicken) actin filament organization [GO:0007015]; vesicle transport along actin filament [GO:0030050] GO:0000146; GO:0005524; GO:0005737; GO:0005886; GO:0005902; GO:0005938; GO:0007015; GO:0015629; GO:0016459; GO:0030050; GO:0031410; GO:0031982; GO:0032587; GO:0051015; GO:0060171 35828 XM_044317196.1 0 0 0 0 17 Q0VBU9 3.38e-67 Phospholipid phosphatase 4 (EC 3.1.3.4) (EC 3.6.1.75) Mus musculus (Mouse) blastocyst hatching [GO:0001835]; phospholipid dephosphorylation [GO:0046839]; phospholipid metabolic process [GO:0006644]; regulation of calcium ion import [GO:0090279] GO:0000810; GO:0001835; GO:0006644; GO:0008195; GO:0016020; GO:0042802; GO:0046839; GO:0090279 35829 XM_044325008.1 2 1 11 11 57 Q5XIT9 1.31e-147 Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCase subunit beta) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 2) (3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta) Rattus norvegicus (Rat) coenzyme A metabolic process [GO:0015936]; leucine catabolic process [GO:0006552] GO:0002169; GO:0004485; GO:0005524; GO:0005739; GO:0005759; GO:0006552; GO:0015936; GO:1905202 35830 XR_003826614.2 0 90 0 11 0 NA NA NA NA NA NA 35831 XM_044324083.1 4 0 0 7 0 NA NA NA NA NA NA 35832 XM_029345516.2 1157 871 522 883 925 Q0IHH9 1.73e-174 Speckle-type POZ protein B Xenopus laevis (African clawed frog) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567] GO:0005634; GO:0016567; GO:0016607; GO:0031463; GO:0043161 35833 XM_029337569.2 12 0 0 0 14 NA NA NA NA NA NA 35834 XM_044327524.1 5 0 272 0 415 Q8BV79 0 TPR and ankyrin repeat-containing protein 1 (Lupus brain antigen 1) Mus musculus (Mouse) NA NA 35835 XM_044327524.1 5 0 272 0 415 Q8BV79 0 TPR and ankyrin repeat-containing protein 1 (Lupus brain antigen 1) Mus musculus (Mouse) NA NA 35836 XM_029343765.2 445 380 259 467 262 NA NA NA NA NA NA 35837 XM_044314883.1 0 1 3 4 6 NA NA NA NA NA NA 35838 XM_044312980.1 14 560 87 24 49 NA NA NA NA NA NA 35839 XR_006395424.1 17 1 1 16 13 NA NA NA NA NA NA 35840 XM_044326612.1 9 99 0 837 280 Q91ZV7 4.22e-51 Plexin domain-containing protein 1 (Tumor endothelial marker 7) Mus musculus (Mouse) spinal cord development [GO:0021510] GO:0005737; GO:0005886; GO:0005923; GO:0021510; GO:0030425; GO:0043025; GO:0043235 35841 XR_006391324.1 2 12 4 22 69 NA NA NA NA NA NA 35842 XM_029343202.2 43 14 96 53 7 NA NA NA NA NA NA 35843 XR_006393231.1 9 8 1 13 10 NA NA NA NA NA NA 35844 XM_044326785.1 66 147 43 32 27 NA NA NA NA NA NA 35845 XM_029328608.2 14 18 5 63 75 Q6AY61 5.02e-39 Serine protease 23 (EC 3.4.21.-) Rattus norvegicus (Rat) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 35846 XR_006391978.1 65 34 50 36 29 NA NA NA NA NA NA 35847 XM_044320910.1 16 0 23 74 0 NA NA NA NA NA NA 35848 XM_044311074.1 3 6 17 8 0 NA NA NA NA NA NA 35849 XM_044307164.1 1614 2403 1412 1789 2620 NA NA NA NA NA NA 35850 XR_006394755.1 342 489 475 247 195 NA NA NA NA NA NA 35851 XM_044322656.1 3 3 0 8 0 NA NA NA NA NA NA 35852 XM_044328687.1 27 117 64 321 98 P16065 0 Speract receptor (EC 4.6.1.2) (Guanylate cyclase) Strongylocentrotus purpuratus (Purple sea urchin) cGMP biosynthetic process [GO:0006182]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]; receptor guanylyl cyclase signaling pathway [GO:0007168]; signal transduction [GO:0007165] GO:0001653; GO:0004383; GO:0004672; GO:0005524; GO:0005525; GO:0005886; GO:0006182; GO:0006468; GO:0007165; GO:0007168; GO:0035556 35853 XM_029349199.2 166 63 117 44 69 NA NA NA NA NA NA 35854 XM_029349868.2 185 0 76 0 216 P50211 1.03e-123 Insulin gene enhancer protein ISL-1 (Islet-1) Gallus gallus (Chicken) atrial septum morphogenesis [GO:0060413]; axonogenesis [GO:0007409]; canonical Wnt signaling pathway [GO:0060070]; cardiac cell fate determination [GO:0060913]; cardiac muscle cell myoblast differentiation [GO:0060379]; cardiac right ventricle morphogenesis [GO:0003215]; cell population proliferation [GO:0008283]; endocardial cushion morphogenesis [GO:0003203]; heart development [GO:0007507]; innervation [GO:0060384]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural crest cell migration [GO:0001755]; neuron fate specification [GO:0048665]; outflow tract septum morphogenesis [GO:0003148]; pancreas development [GO:0031016]; peripheral nervous system neuron axonogenesis [GO:0048936]; pharyngeal system development [GO:0060037]; pituitary gland development [GO:0021983]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA binding [GO:0043388]; positive regulation of granulocyte colony-stimulating factor production [GO:0071657]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of histone acetylation [GO:0035066]; positive regulation of insulin secretion [GO:0032024]; positive regulation of interleukin-1 alpha production [GO:0032730]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type II interferon production [GO:0032729]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of secondary heart field cardioblast proliferation [GO:0003266]; regulation of transcription by RNA polymerase II [GO:0006357]; retinal ganglion cell axon guidance [GO:0031290]; secondary heart field specification [GO:0003139]; sensory system development [GO:0048880]; sinoatrial node cell development [GO:0060931]; spinal cord motor neuron cell fate specification [GO:0021520]; transcription by RNA polymerase II [GO:0006366]; trigeminal nerve development [GO:0021559]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; visceral motor neuron differentiation [GO:0021524] GO:0000122; GO:0000785; GO:0000978; GO:0000981; GO:0000987; GO:0001228; GO:0001755; GO:0003139; GO:0003148; GO:0003203; GO:0003215; GO:0003266; GO:0005634; GO:0006357; GO:0006366; GO:0007409; GO:0007507; GO:0008283; GO:0008284; GO:0010575; GO:0021520; GO:0021524; GO:0021559; GO:0021983; GO:0031016; GO:0031290; GO:0032024; GO:0032725; GO:0032729; GO:0032730; GO:0032731; GO:0032735; GO:0032755; GO:0032760; GO:0035066; GO:0042531; GO:0043388; GO:0043425; GO:0043524; GO:0045597; GO:0045665; GO:0045766; GO:0045892; GO:0045944; GO:0046872; GO:0048665; GO:0048880; GO:0048936; GO:0050728; GO:0055010; GO:0060037; GO:0060070; GO:0060379; GO:0060384; GO:0060413; GO:0060913; GO:0060931; GO:0061629; GO:0071657; GO:0086091; GO:0090090; GO:1990841 35855 XM_044319765.1 523 714 246 377 696 Q4R7U8 1.03e-65 Isoaspartyl peptidase/L-asparaginase (EC 3.4.19.5) (EC 3.5.1.1) (Asparaginase-like protein 1) (Beta-aspartyl-peptidase) (Isoaspartyl dipeptidase) (L-asparagine amidohydrolase) [Cleaved into: Isoaspartyl peptidase/L-asparaginase alpha chain; Isoaspartyl peptidase/L-asparaginase beta chain] Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) asparagine catabolic process via L-aspartate [GO:0033345]; proteolysis [GO:0006508] GO:0001917; GO:0004067; GO:0005737; GO:0006508; GO:0008798; GO:0033345 35856 XM_044329025.1 2 1 0 0 24 NA NA NA NA NA NA 35857 XM_029340675.2 788 1331 1030 1125 1014 NA NA NA NA NA NA 35858 XM_029331832.2 1341 1360 1309 2329 2638 A1ZA47 3.2e-46 PDZ and LIM domain protein Zasp (Z band alternatively spliced PDZ-motif protein) Drosophila melanogaster (Fruit fly) actin cytoskeleton organization [GO:0030036]; muscle structure development [GO:0061061]; myofibril assembly [GO:0030239]; regulation of cell-matrix adhesion [GO:0001952] GO:0001725; GO:0001952; GO:0003779; GO:0005912; GO:0005915; GO:0005925; GO:0005927; GO:0015629; GO:0016323; GO:0030018; GO:0030036; GO:0030239; GO:0031252; GO:0031941; GO:0042805; GO:0045177; GO:0045178; GO:0046872; GO:0051371; GO:0061061 35859 XM_029333726.2 376 15 319 20 0 NA NA NA NA NA NA 35860 XM_029334394.2 18 16 4 29 8 O54912 6.14e-28 Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1) (Two pore K(+) channel KT3.1) Rattus norvegicus (Rat) brain development [GO:0007420]; cellular response to hypoxia [GO:0071456]; cellular response to zinc ion [GO:0071294]; cochlea development [GO:0090102]; ion transmembrane transport [GO:0034220]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; positive regulation of voltage-gated potassium channel activity [GO:1903818]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of resting membrane potential [GO:0060075]; response to xenobiotic stimulus [GO:0009410]; stabilization of membrane potential [GO:0030322] GO:0005216; GO:0005252; GO:0005886; GO:0006813; GO:0007420; GO:0008022; GO:0009410; GO:0015271; GO:0022841; GO:0030322; GO:0034220; GO:0044548; GO:0051481; GO:0060075; GO:0071294; GO:0071456; GO:0071805; GO:0090102; GO:1903818 35861 XM_044318082.1 49 41 64 41 209 NA NA NA NA NA NA 35862 XM_029337249.2 635 332 512 527 482 Q5ZIE8 1.98e-23 Activating transcription factor 7-interacting protein 1 (MBD1-containing chromatin-associated factor 1) Gallus gallus (Chicken) positive regulation of DNA methylation-dependent heterochromatin formation [GO:0090309]; protein stabilization [GO:0050821]; regulation of DNA-templated transcription [GO:0006355]; regulation of protein stability [GO:0031647] GO:0003712; GO:0005634; GO:0005667; GO:0006355; GO:0031647; GO:0050821; GO:0090309 35863 XM_044312339.1 14 6 6 2 5 NA NA NA NA NA NA 35864 XM_044312824.1 14 2 8 20 5 NA NA NA NA NA NA 35865 XM_044317853.1 172 0 154 275 75 Q4KLT3 3.36e-138 Probable tRNA (uracil-O(2)-)-methyltransferase (EC 2.1.1.211) (Methyltransferase-like protein 19) Xenopus laevis (African clawed frog) NA GO:0005737; GO:0046872; GO:0052665 35866 XM_029351802.2 68 250 24 117 55 Q66HG5 0 Transmembrane 9 superfamily member 2 Rattus norvegicus (Rat) ceramide metabolic process [GO:0006672]; glycosphingolipid biosynthetic process [GO:0006688]; protein localization to membrane [GO:0072657]; regulation of heparan sulfate proteoglycan biosynthetic process [GO:0010908] GO:0005794; GO:0005856; GO:0006672; GO:0006688; GO:0010008; GO:0010908; GO:0016020; GO:0072657 35867 XR_006396250.1 0 0 0 0 7 NA NA NA NA NA NA 35868 XM_029351020.2 1 0 11 0 0 NA NA NA NA NA NA 35869 XR_006393645.1 10321 26552 3822 16581 26944 NA NA NA NA NA NA 35870 XM_044310226.1 0 8 5 0 394 NA NA NA NA NA NA 35871 XM_029341632.2 70 16 27 110 37 NA NA NA NA NA NA 35872 XM_044314891.1 105 0 17 33 0 NA NA NA NA NA NA 35873 XR_006393228.1 102 324 152 113 99 NA NA NA NA NA NA 35874 XM_029355435.2 537 632 171 457 423 O88350 5.95e-72 Serine hydrolase RBBP9 (EC 3.-.-.-) (B5T-overexpressed gene protein) (Protein BOG) (Retinoblastoma-binding protein 9) (RBBP-9) Rattus norvegicus (Rat) positive regulation of gene expression [GO:0010628]; regulation of cell population proliferation [GO:0042127]; response to nematode [GO:0009624]; type II pneumocyte differentiation [GO:0060510] GO:0005654; GO:0009624; GO:0010628; GO:0016787; GO:0042127; GO:0060510 35875 XM_029333727.2 0 16 5 21 21 Q5U3G6 6.99e-102 Protein YIF1B (YIP1-interacting factor homolog B) Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; protein transport [GO:0015031]; sperm flagellum assembly [GO:0120316] GO:0000139; GO:0005783; GO:0005789; GO:0005793; GO:0005794; GO:0006888; GO:0015031; GO:0030134; GO:0033116; GO:0060271; GO:0120316 35876 XR_006392172.1 12 64 35 21 29 NA NA NA NA NA NA 35877 XM_044314159.1 23 25 7 21 69 NA NA NA NA NA NA 35878 XM_044313307.1 9 7 27 2 6 Q5R4R7 1.03e-37 PHD finger protein 24 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0046872 35879 XM_044311996.1 4 3 84 18 15 NA NA NA NA NA NA 35880 XM_029356593.2 216 185 159 130 262 Q2KIB9 1.06e-45 Ribonuclease P protein subunit p29 Bos taurus (Bovine) rRNA processing [GO:0006364]; tRNA 5'-leader removal [GO:0001682] GO:0000172; GO:0001682; GO:0004526; GO:0005654; GO:0005730; GO:0006364; GO:0030677; GO:0030681; GO:0033204 35881 XM_029337120.2 44 27 26 8 92 NA NA NA NA NA NA 35882 XM_044328996.1 502 349 197 268 443 Q5RF65 6.23e-158 Cytosolic beta-glucosidase (EC 3.2.1.21) (Cytosolic galactosylceramidase) (EC 3.2.1.46) (Cytosolic glucosylceramidase) (EC 3.2.1.45) (Cytosolic glycosylceramidase) (Cytosolic GCase) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) beta-glucoside catabolic process [GO:1901805]; carbohydrate metabolic process [GO:0005975]; galactosylceramide catabolic process [GO:0006683]; glucosylceramide catabolic process [GO:0006680] GO:0004336; GO:0004348; GO:0004565; GO:0005829; GO:0005975; GO:0006680; GO:0006683; GO:0008422; GO:0017042; GO:0102483; GO:1901805 35883 XM_044316681.1 287 51 61 155 121 NA NA NA NA NA NA 35884 XR_003827470.2 88 111 32 103 221 NA NA NA NA NA NA 35885 XM_029337367.2 1223 852 503 1361 795 P43378 2.19e-149 Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase MEG2) Homo sapiens (Human) negative regulation of neuron projection development [GO:0010977]; peptidyl-tyrosine dephosphorylation [GO:0035335]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein dephosphorylation [GO:0006470] GO:0004725; GO:0004726; GO:0005654; GO:0005737; GO:0006470; GO:0010977; GO:0035335; GO:0044306; GO:1903078 35886 XM_029338121.2 50 174 46 97 64 NA NA NA NA NA NA 35887 XM_029328684.2 0 31 0 70 121 NA NA NA NA NA NA 35888 XM_029335233.2 9 4 5 29 81 Q6NYL5 4.76e-152 Alanine aminotransferase 2-like (ALT2) (EC 2.6.1.2) (Glutamate pyruvate transaminase 2) (GPT 2) (Glutamic--alanine transaminase 2) (Glutamic--pyruvic transaminase 2) Danio rerio (Zebrafish) (Brachydanio rerio) 2-oxoglutarate metabolic process [GO:0006103]; biosynthetic process [GO:0009058]; L-alanine catabolic process [GO:0042853]; L-alanine metabolic process [GO:0042851] GO:0004021; GO:0006103; GO:0009058; GO:0030170; GO:0042851; GO:0042853 35889 XM_029358023.2 0 0 0 6 0 P23819 4.35e-92 Glutamate receptor 2 (GluR-2) (AMPA-selective glutamate receptor 2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (GluA2) Mus musculus (Mouse) cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to glycine [GO:1905430]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966] GO:0000149; GO:0001540; GO:0001919; GO:0004970; GO:0004971; GO:0005234; GO:0005783; GO:0005789; GO:0005886; GO:0007268; GO:0008021; GO:0008092; GO:0009986; GO:0014069; GO:0015276; GO:0015277; GO:0016020; GO:0019865; GO:0019901; GO:0030165; GO:0030424; GO:0030425; GO:0030426; GO:0030672; GO:0031623; GO:0032279; GO:0032281; GO:0032590; GO:0032839; GO:0032991; GO:0035235; GO:0035254; GO:0035255; GO:0036477; GO:0038023; GO:0042734; GO:0042802; GO:0043005; GO:0043025; GO:0043195; GO:0043197; GO:0043198; GO:0043204; GO:0044326; GO:0044327; GO:0044877; GO:0045184; GO:0045202; GO:0045211; GO:0048787; GO:0050806; GO:0051117; GO:0051262; GO:0051966; GO:0097060; GO:0097110; GO:0098685; GO:0098793; GO:0098839; GO:0098978; GO:0099507; GO:0099544; GO:0106033; GO:1904315; GO:1905430; GO:1990416 35890 XM_029333440.2 268 194 91 106 187 Q99JG3 7.99e-25 Annexin A13 (Annexin XIII) (Annexin-13) Mus musculus (Mouse) NA GO:0001786; GO:0005509; GO:0005544; GO:0005654; GO:0005737; GO:0005886; GO:0016324; GO:0019898; GO:0031410; GO:1901611 35891 XM_044307904.1 0 25 2 28 26 NA NA NA NA NA NA 35892 XM_044322350.1 0 68 0 0 0 P06845 3.77e-22 Tyrosinase (EC 1.14.18.1) (Monophenol monooxygenase) Streptomyces glaucescens melanin biosynthetic process [GO:0042438] GO:0004503; GO:0042438; GO:0046872 35893 XR_006395181.1 14 13 16 2 18 NA NA NA NA NA NA 35894 XM_029335963.2 535 261 350 616 539 Q9JL56 5.54e-73 Glycerophosphodiester phosphodiesterase 1 (Glycerophosphoinositol glycerophosphodiesterase GDE1) (EC 3.1.4.44) (Lysophospholipase D GDE1) (EC 3.1.4.-) (Membrane-interacting protein of RGS16) Mus musculus (Mouse) ethanolamine metabolic process [GO:0006580]; G protein-coupled receptor signaling pathway [GO:0007186]; N-acylethanolamine metabolic process [GO:0070291]; phospholipid metabolic process [GO:0006644] GO:0004622; GO:0005886; GO:0006580; GO:0006644; GO:0007186; GO:0008081; GO:0008889; GO:0016020; GO:0030659; GO:0046872; GO:0047395; GO:0070291 35895 XM_029352054.2 247 205 474 87 140 NA NA NA NA NA NA 35896 XM_029344413.2 1351 1524 1225 2480 3107 Q91VY9 5.62e-72 Cytoplasmic 60S subunit biogenesis factor ZNF622 (Zinc finger protein 622) Mus musculus (Mouse) intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; positive regulation of apoptotic process [GO:0043065]; positive regulation of JNK cascade [GO:0046330]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; ribosomal large subunit biogenesis [GO:0042273] GO:0003676; GO:0005654; GO:0005730; GO:0005794; GO:0005829; GO:0008270; GO:0008631; GO:0030687; GO:0033674; GO:0042273; GO:0043065; GO:0043410; GO:0046330; GO:1990275 35897 XM_029344413.2 1351 1524 1225 2480 3107 Q91VY9 8.57e-26 Cytoplasmic 60S subunit biogenesis factor ZNF622 (Zinc finger protein 622) Mus musculus (Mouse) intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; positive regulation of apoptotic process [GO:0043065]; positive regulation of JNK cascade [GO:0046330]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; ribosomal large subunit biogenesis [GO:0042273] GO:0003676; GO:0005654; GO:0005730; GO:0005794; GO:0005829; GO:0008270; GO:0008631; GO:0030687; GO:0033674; GO:0042273; GO:0043065; GO:0043410; GO:0046330; GO:1990275 35898 XM_044317655.1 645 430 252 324 882 P0C928 0 Regulator of telomere elongation helicase 1 (EC 3.6.4.12) Danio rerio (Zebrafish) (Brachydanio rerio) DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; negative regulation of DNA recombination [GO:0045910]; negative regulation of t-circle formation [GO:1904430]; regulation of double-strand break repair via homologous recombination [GO:0010569]; telomeric loop disassembly [GO:0090657] GO:0003677; GO:0003678; GO:0005524; GO:0005634; GO:0006260; GO:0006281; GO:0006310; GO:0010569; GO:0016887; GO:0032508; GO:0045910; GO:0046872; GO:0051539; GO:0070182; GO:0090657; GO:1904430 35899 XM_029355341.2 471 758 463 1430 1223 Q6IWH7 0 Anoctamin-7 (Dresden transmembrane protein of the prostate) (D-TMPP) (IPCA-5) (New gene expressed in prostate) (Prostate cancer-associated protein 5) (Transmembrane protein 16G) Homo sapiens (Human) calcium activated phospholipid scrambling [GO:0061588]; chloride transmembrane transport [GO:1902476]; chloride transport [GO:0006821]; ion transmembrane transport [GO:0034220]; transmembrane transport [GO:0055085] GO:0005229; GO:0005254; GO:0005783; GO:0005829; GO:0005886; GO:0006821; GO:0034220; GO:0046983; GO:0055085; GO:0061588; GO:0070161; GO:1902476 35900 XM_029338577.2 113 560 0 879 173 NA NA NA NA NA NA 35901 XM_029335677.2 134 96 54 166 100 P07314 1.07e-149 Glutathione hydrolase 1 proenzyme (EC 3.4.19.13) (Gamma-glutamyltransferase 1) (Gamma-glutamyltranspeptidase 1) (GGT 1) (EC 2.3.2.2) (Leukotriene-C4 hydrolase) (EC 3.4.19.14) (CD antigen CD224) [Cleaved into: Glutathione hydrolase 1 heavy chain; Glutathione hydrolase 1 light chain] Rattus norvegicus (Rat) aging [GO:0007568]; amino acid metabolic process [GO:0006520]; cellular response to oxidative stress [GO:0034599]; cysteine biosynthetic process [GO:0019344]; fatty acid metabolic process [GO:0006631]; glutamate metabolic process [GO:0006536]; glutathione biosynthetic process [GO:0006750]; glutathione catabolic process [GO:0006751]; hepatoblast differentiation [GO:0061017]; hepatocyte differentiation [GO:0070365]; leukotriene D4 biosynthetic process [GO:1901750]; leukotriene metabolic process [GO:0006691]; liver regeneration [GO:0097421]; peptide modification [GO:0031179]; proteolysis [GO:0006508]; regulation of immune system process [GO:0002682]; regulation of inflammatory response [GO:0050727]; response to alcohol [GO:0097305]; response to estradiol [GO:0032355]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]; spermatogenesis [GO:0007283]; zymogen activation [GO:0031638] GO:0000048; GO:0002682; GO:0002951; GO:0005615; GO:0005886; GO:0006508; GO:0006520; GO:0006536; GO:0006631; GO:0006691; GO:0006750; GO:0006751; GO:0007283; GO:0007568; GO:0016755; GO:0019344; GO:0031179; GO:0031638; GO:0031982; GO:0032355; GO:0032496; GO:0034599; GO:0034612; GO:0036374; GO:0050727; GO:0061017; GO:0070365; GO:0097305; GO:0097421; GO:0102953; GO:0103068; GO:1901750 35902 XM_029334025.2 34 35 10 26 0 Q9VFB2 3.67e-35 28S ribosomal protein S10, mitochondrial (MRP-S10) (S10mt) Drosophila melanogaster (Fruit fly) mitochondrial translation [GO:0032543] GO:0003735; GO:0005739; GO:0005763; GO:0032543 35903 XR_003826610.2 0 14 0 0 0 NA NA NA NA NA NA 35904 XM_029348720.2 102 0 0 0 80 Q6AYE3 2.74e-127 Transcriptional adapter 2-alpha (Transcriptional adapter 2-like) (ADA2-like protein) Rattus norvegicus (Rat) chromatin remodeling [GO:0006338]; histone H3 acetylation [GO:0043966]; histone H3-K14 acetylation [GO:0044154]; mitotic cell cycle [GO:0000278]; positive regulation of histone acetylation [GO:0035066]; regulation of cell cycle [GO:0051726]; regulation of cell division [GO:0051302]; regulation of DNA-templated transcription [GO:0006355]; regulation of embryonic development [GO:0045995]; regulation of histone deacetylation [GO:0031063]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tubulin deacetylation [GO:0090043] GO:0000124; GO:0000278; GO:0001932; GO:0003677; GO:0003682; GO:0003713; GO:0005634; GO:0006338; GO:0006355; GO:0006357; GO:0008270; GO:0031063; GO:0031647; GO:0035066; GO:0043966; GO:0044154; GO:0045995; GO:0051302; GO:0051726; GO:0070461; GO:0072686; GO:0090043; GO:0140672 35905 XM_044313514.1 3 10 3 0 10 NA NA NA NA NA NA 35906 XM_044325125.1 452 267 150 1193 649 B3EX02 5.57e-124 MAM and fibronectin type III domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 35907 XM_044325125.1 452 267 150 1193 649 B3EX02 2.76e-122 MAM and fibronectin type III domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 35908 XM_044325125.1 452 267 150 1193 649 B3EX02 2.63e-112 MAM and fibronectin type III domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 35909 XM_044325125.1 452 267 150 1193 649 B3EX02 1.36e-23 MAM and fibronectin type III domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 35910 XR_006396966.1 5 3 42 15 21 NA NA NA NA NA NA 35911 XM_044308295.1 3213 1834 1259 2609 2596 NA NA NA NA NA NA 35912 XM_044317126.1 3 0 0 3 15 NA NA NA NA NA NA 35913 XM_044313374.1 15 31 0 0 0 Q4R964 1.76e-34 Probable inactive allantoicase (Allantoate amidinohydrolase) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) allantoin catabolic process [GO:0000256] GO:0000256; GO:0004037 35914 XR_003827986.2 618 218 207 435 397 NA NA NA NA NA NA 35915 XM_029345091.2 0 0 3 0 30 NA NA NA NA NA NA 35916 XM_029329051.2 41 24 26 52 42 NA NA NA NA NA NA 35917 XM_029335106.2 1479 1302 564 734 849 NA NA NA NA NA NA 35918 XR_006396907.1 220 271 123 100 71 NA NA NA NA NA NA 35919 XM_044329233.1 4503 3622 1573 3499 3511 O35920 0 Calpain-9 (EC 3.4.22.-) (Digestive tract-specific calpain) (New calpain 4) (nCL-4) Rattus norvegicus (Rat) proteolysis [GO:0006508] GO:0004198; GO:0005509; GO:0005737; GO:0006508 35920 XM_029323739.2 16956 13485 6464 14850 15183 P53812 4.19e-89 Phosphatidylinositol transfer protein beta isoform (PI-TP-beta) (PtdIns transfer protein beta) (PtdInsTP beta) Rattus norvegicus (Rat) in utero embryonic development [GO:0001701]; phospholipid transport [GO:0015914]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] GO:0000139; GO:0001701; GO:0005737; GO:0005789; GO:0005794; GO:0006890; GO:0008525; GO:0008526; GO:0015914; GO:0031210; GO:0035091; GO:0120019; GO:0140338 35921 XR_006395540.1 44 40 63 37 90 NA NA NA NA NA NA 35922 XM_044328866.1 36 0 0 0 34 NA NA NA NA NA NA 35923 XM_044319063.1 3388 2089 1760 2602 2576 Q80U16 2.37e-31 Rho family-interacting cell polarization regulator 2 Mus musculus (Mouse) auditory receptor cell stereocilium organization [GO:0060088]; cell adhesion [GO:0007155]; cellular response to chemokine [GO:1990869]; cellular response to mechanical stimulus [GO:0071260]; chemotaxis [GO:0006935]; establishment of protein localization [GO:0045184]; muscle organ development [GO:0007517]; negative regulation of cell adhesion [GO:0007162]; negative regulation of establishment of T cell polarity [GO:1903904]; negative regulation of protein localization to cell leading edge [GO:1905872]; negative regulation of Rho guanyl-nucleotide exchange factor activity [GO:2001107]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of T cell migration [GO:2000405]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of neutrophil extravasation [GO:2000391]; protein homooligomerization [GO:0051260]; regulation of cell cycle [GO:0051726]; regulation of establishment of cell polarity [GO:2000114]; regulation of mitotic spindle assembly [GO:1901673]; sensory perception of sound [GO:0007605] GO:0005737; GO:0005829; GO:0005856; GO:0006935; GO:0007155; GO:0007162; GO:0007517; GO:0007605; GO:0016324; GO:0030175; GO:0032420; GO:0035024; GO:0042130; GO:0042802; GO:0045184; GO:0045663; GO:0051260; GO:0051491; GO:0051726; GO:0060088; GO:0060171; GO:0071260; GO:0071889; GO:0090023; GO:1901673; GO:1901741; GO:1903904; GO:1905872; GO:1990869; GO:2000114; GO:2000391; GO:2000405; GO:2001107 35924 XR_006398119.1 1 0 8 9 7 NA NA NA NA NA NA 35925 XM_029332353.2 386 316 205 192 166 Q8BG58 1.27e-62 Transmembrane prolyl 4-hydroxylase (P4H-TM) (EC 1.14.11.29) (Hypoxia-inducible factor prolyl hydroxylase 4) (HIF-PH4) (HIF-prolyl hydroxylase 4) (HPH-4) Mus musculus (Mouse) peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; regulation of erythrocyte differentiation [GO:0045646] GO:0004656; GO:0005506; GO:0005509; GO:0005783; GO:0005789; GO:0016706; GO:0018401; GO:0031418; GO:0045646 35926 XM_044306842.1 78 30 11 284 62 NA NA NA NA NA NA 35927 XM_044312028.1 30 11 6 25 98 NA NA NA NA NA NA 35928 XM_044308280.1 367 142 248 320 311 NA NA NA NA NA NA 35929 XM_044320080.1 179 853 140 222 254 P10079 0 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 35930 XM_044320080.1 179 853 140 222 254 P10079 0 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 35931 XM_044320080.1 179 853 140 222 254 P10079 0 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 35932 XM_044320080.1 179 853 140 222 254 P10079 0 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 35933 XM_044320080.1 179 853 140 222 254 P10079 3.65e-169 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 35934 XM_044320080.1 179 853 140 222 254 P10079 1.81e-143 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 35935 XM_044320080.1 179 853 140 222 254 P10079 9.39e-132 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 35936 XM_044316770.1 20 31 36 142 108 Q9H4G4 9.73e-21 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Homo sapiens (Human) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070062; GO:0070374 35937 XM_044307202.1 72 74 43 55 183 NA NA NA NA NA NA 35938 XM_029341203.2 0 22 18 65 22 NA NA NA NA NA NA 35939 XM_029340960.2 469 165 209 454 306 NA NA NA NA NA NA 35940 XR_006395890.1 134 24 39 52 185 Q9UJA9 1.03e-47 Ectonucleotide pyrophosphatase/phosphodiesterase family member 5 (E-NPP 5) (NPP-5) (EC 3.1.-.-) Homo sapiens (Human) cell communication [GO:0007154] GO:0000210; GO:0005576; GO:0005886; GO:0007154; GO:0008270 35941 XM_044318212.1 0 5 44 0 182 NA NA NA NA NA NA 35942 XM_029342498.2 249 163 25 198 68 Q6ZN57 1.23e-53 Zinc finger protein ZFP2 (Zfp-2) (Zinc finger protein 751) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 35943 XM_029342498.2 249 163 25 198 68 Q6ZN57 4.3e-49 Zinc finger protein ZFP2 (Zfp-2) (Zinc finger protein 751) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 35944 XM_029342498.2 249 163 25 198 68 Q6ZN57 2.22e-48 Zinc finger protein ZFP2 (Zfp-2) (Zinc finger protein 751) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 35945 XM_029342498.2 249 163 25 198 68 Q6ZN57 3.6e-48 Zinc finger protein ZFP2 (Zfp-2) (Zinc finger protein 751) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 35946 XM_029342498.2 249 163 25 198 68 Q6ZN57 1.66e-47 Zinc finger protein ZFP2 (Zfp-2) (Zinc finger protein 751) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 35947 XM_029342498.2 249 163 25 198 68 Q6ZN57 9.22e-46 Zinc finger protein ZFP2 (Zfp-2) (Zinc finger protein 751) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 35948 XM_029342498.2 249 163 25 198 68 Q6ZN57 2.22e-41 Zinc finger protein ZFP2 (Zfp-2) (Zinc finger protein 751) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 35949 XR_006393084.1 12 3 32 0 12 NA NA NA NA NA NA 35950 XM_044313644.1 6 5 0 0 0 NA NA NA NA NA NA 35951 XM_029351584.2 11749 12978 7240 9101 4083 P35069 3.35e-59 Histone H2B.3 Tigriopus californicus (Marine copepod) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0044877; GO:0046982 35952 XM_044313567.1 1853 1334 463 1255 316 Q02253 0 Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial (MMSDH) (Malonate-semialdehyde dehydrogenase [acylating]) (EC 1.2.1.18) (EC 1.2.1.27) (Aldehyde dehydrogenase family 6 member A1) Rattus norvegicus (Rat) beta-alanine catabolic process [GO:0019484]; brown fat cell differentiation [GO:0050873]; thymine catabolic process [GO:0006210]; thymine metabolic process [GO:0019859]; valine catabolic process [GO:0006574]; valine metabolic process [GO:0006573] GO:0000062; GO:0004491; GO:0005739; GO:0006210; GO:0006573; GO:0006574; GO:0016790; GO:0018478; GO:0019484; GO:0019859; GO:0050873; GO:0102662 35953 XM_029341022.2 96 47 45 52 281 P07949 1.06e-52 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; axon guidance [GO:0007411]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; lymphocyte migration into lymphoid organs [GO:0097021]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; posterior midgut development [GO:0007497]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006468; GO:0006919; GO:0007156; GO:0007158; GO:0007165; GO:0007169; GO:0007411; GO:0007497; GO:0009410; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0038023; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0097021; GO:0098797; GO:2001241 35954 XM_044325755.1 4 4 17 3 28 NA NA NA NA NA NA 35955 XM_029357728.2 9360 6737 4156 5923 7081 NA NA NA NA NA NA 35956 XM_029335995.2 11981 10078 5115 10091 8286 A0A0R4IVA4 1.16e-80 Dual specificity protein phosphatase CDC14AB (EC 3.1.3.16) (EC 3.1.3.48) (CDC14 cell division cycle 14 homolog AB) Danio rerio (Zebrafish) (Brachydanio rerio) cell cycle [GO:0007049]; cell division [GO:0051301]; cilium assembly [GO:0060271]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of cytokinesis [GO:0032467]; protein dephosphorylation [GO:0006470]; regulation of exit from mitosis [GO:0007096] GO:0000226; GO:0000922; GO:0004722; GO:0004725; GO:0005730; GO:0005737; GO:0005813; GO:0006470; GO:0007049; GO:0007096; GO:0008138; GO:0017018; GO:0032467; GO:0051301; GO:0060271; GO:0072686; GO:1902636 35957 XM_044326969.1 9 45 6 4 11 Q94K49 3.77e-32 Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1 (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) epigenetic regulation of gene expression [GO:0040029] GO:0003682; GO:0004518; GO:0005634; GO:0035098; GO:0035102; GO:0040029; GO:0046872 35958 XM_044307346.1 17 5 31 0 0 NA NA NA NA NA NA 35959 XM_029334486.2 4977 7179 5029 3797 2732 Q9CXL1 9.82e-49 Transmembrane protein 50A (Small membrane protein 1) Mus musculus (Mouse) late endosome to vacuole transport via multivesicular body sorting pathway [GO:0032511] GO:0005737; GO:0005783; GO:0016020; GO:0032511; GO:0043025; GO:0097386 35960 XM_029338720.2 1489 848 701 1156 1256 Q6NSQ7 8.58e-90 Protein LTV1 homolog Mus musculus (Mouse) ribosomal small subunit biogenesis [GO:0042274]; ribosomal small subunit export from nucleus [GO:0000056] GO:0000056; GO:0005634; GO:0005654; GO:0005829; GO:0030688; GO:0042274 35961 XM_029349688.2 812 881 406 683 840 O14772 4.28e-134 Fucose-1-phosphate guanylyltransferase (EC 2.7.7.30) (GDP-L-fucose diphosphorylase) (GDP-L-fucose pyrophosphorylase) Homo sapiens (Human) fucose metabolic process [GO:0006004] GO:0003824; GO:0005525; GO:0005737; GO:0005829; GO:0006004; GO:0047341 35962 XM_029329903.2 99 35 164 63 64 P47972 1.19e-23 Neuronal pentraxin-2 (NP2) (Neuronal pentraxin II) (NP-II) Homo sapiens (Human) associative learning [GO:0008306]; chemical synaptic transmission [GO:0007268]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962] GO:0005576; GO:0007268; GO:0008306; GO:0030246; GO:0046872; GO:0098962; GO:0098978 35963 XR_006395025.1 160 124 139 125 36 NA NA NA NA NA NA 35964 XR_003826183.2 0 102 0 47 99 NA NA NA NA NA NA 35965 XM_044309061.1 0 3 0 41 0 Q3UQ28 1.28e-31 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 35966 XM_044309061.1 0 3 0 41 0 Q3UQ28 6.19e-29 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 35967 XM_029337544.2 69 110 50 92 39 P70236 7.25e-137 Dual specificity mitogen-activated protein kinase kinase 6 (MAP kinase kinase 6) (MAPKK 6) (EC 2.7.12.2) (MAPK/ERK kinase 6) (MEK 6) (SAPKK3) Mus musculus (Mouse) apoptotic process [GO:0006915]; bone development [GO:0060348]; cardiac muscle contraction [GO:0060048]; cellular response to sorbitol [GO:0072709]; MAPK cascade [GO:0000165]; negative regulation of cold-induced thermogenesis [GO:0120163]; osteoblast differentiation [GO:0001649]; ovulation cycle process [GO:0022602]; positive regulation of apoptotic process [GO:0043065]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein phosphorylation [GO:0001934]; protein phosphorylation [GO:0006468]; response to ischemia [GO:0002931]; response to xenobiotic stimulus [GO:0009410]; stress-activated MAPK cascade [GO:0051403] GO:0000165; GO:0001649; GO:0001934; GO:0002931; GO:0004674; GO:0004708; GO:0004713; GO:0005524; GO:0005654; GO:0005829; GO:0005856; GO:0006468; GO:0006915; GO:0009410; GO:0019211; GO:0019901; GO:0022602; GO:0032308; GO:0042802; GO:0043065; GO:0043406; GO:0043410; GO:0043539; GO:0051403; GO:0051770; GO:0060048; GO:0060348; GO:0072709; GO:0106310; GO:0120163; GO:0140537 35968 XM_029341295.2 19594 15778 11135 12149 6919 Q99538 6.55e-147 Legumain (EC 3.4.22.34) (Asparaginyl endopeptidase) (Protease, cysteine 1) Homo sapiens (Human) activation of cysteine-type endopeptidase activity [GO:0097202]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; associative learning [GO:0008306]; cellular response to amyloid-beta [GO:1904646]; cellular response to calcium ion [GO:0071277]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; dendritic spine organization [GO:0097061]; memory [GO:0007613]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of gene expression [GO:0010629]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of monocyte chemotaxis [GO:0090026]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; receptor catabolic process [GO:0032801]; renal system process [GO:0003014]; response to acidic pH [GO:0010447]; self proteolysis [GO:0097264]; vacuolar protein processing [GO:0006624]; vitamin D metabolic process [GO:0042359] GO:0003014; GO:0004197; GO:0005576; GO:0005737; GO:0005764; GO:0005770; GO:0006508; GO:0006624; GO:0007613; GO:0008233; GO:0008284; GO:0008306; GO:0010447; GO:0010629; GO:0019886; GO:0032801; GO:0035729; GO:0036021; GO:0040015; GO:0042359; GO:0043202; GO:0043524; GO:0045177; GO:0045931; GO:0048156; GO:0048471; GO:0051603; GO:0070062; GO:0071277; GO:0090026; GO:0097061; GO:0097202; GO:0097264; GO:1900273; GO:1901185; GO:1904646; GO:2001028 35969 XM_044307935.1 24 4 12 22 38 Q99315 1.04e-93 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 35970 XM_044313004.1 7 0 13 21 96 NA NA NA NA NA NA 35971 XM_044323899.1 97 35 202 96 767 O60290 6.76e-35 Zinc finger protein 862 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006355; GO:0046872; GO:0046983 35972 XM_029325025.2 25 0 0 13 0 Q99JY4 7.5e-96 TraB domain-containing protein Mus musculus (Mouse) NA NA 35973 XR_006396274.1 19 18 19 11 2 NA NA NA NA NA NA 35974 XR_006394875.1 33 2 70 23 67 NA NA NA NA NA NA 35975 XM_029344181.2 35 9 43 28 5 NA NA NA NA NA NA 35976 XM_029356867.2 41 31 100 124 65 NA NA NA NA NA NA 35977 XM_029355901.2 48100 45862 23475 52340 35501 O02705 0 Heat shock protein HSP 90-alpha (EC 3.6.4.10) Sus scrofa (Pig) activation of innate immune response [GO:0002218]; cellular response to heat [GO:0034605]; cellular response to virus [GO:0098586]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; protein folding [GO:0006457]; protein stabilization [GO:0050821]; regulation of apoptotic process [GO:0042981]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408] GO:0002218; GO:0002230; GO:0005524; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0005886; GO:0006457; GO:0009408; GO:0009409; GO:0016887; GO:0030235; GO:0030911; GO:0032728; GO:0032991; GO:0034605; GO:0042470; GO:0042981; GO:0043025; GO:0043209; GO:0045429; GO:0046677; GO:0048471; GO:0050821; GO:0051082; GO:0097718; GO:0098586; GO:0140662 35978 XM_029355901.2 48100 45862 23475 52340 35501 O02705 5.5e-104 Heat shock protein HSP 90-alpha (EC 3.6.4.10) Sus scrofa (Pig) activation of innate immune response [GO:0002218]; cellular response to heat [GO:0034605]; cellular response to virus [GO:0098586]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; protein folding [GO:0006457]; protein stabilization [GO:0050821]; regulation of apoptotic process [GO:0042981]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408] GO:0002218; GO:0002230; GO:0005524; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0005886; GO:0006457; GO:0009408; GO:0009409; GO:0016887; GO:0030235; GO:0030911; GO:0032728; GO:0032991; GO:0034605; GO:0042470; GO:0042981; GO:0043025; GO:0043209; GO:0045429; GO:0046677; GO:0048471; GO:0050821; GO:0051082; GO:0097718; GO:0098586; GO:0140662 35979 XM_044309199.1 116 616 21 123 38 NA NA NA NA NA NA 35980 XM_044327470.1 14 62 53 265 126 NA NA NA NA NA NA 35981 XM_044315838.1 85 112 185 63 1360 NA NA NA NA NA NA 35982 XM_029341516.2 0 0 0 99 89 Q02974 2.43e-98 Ketohexokinase (EC 2.7.1.3) (Hepatic fructokinase) Rattus norvegicus (Rat) carbohydrate catabolic process [GO:0016052]; carbohydrate phosphorylation [GO:0046835]; fructose catabolic process [GO:0006001]; fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; fructose metabolic process [GO:0006000]; regulation of glycogen metabolic process [GO:0070873]; response to fructose [GO:0009750]; response to glucose [GO:0009749]; response to insulin [GO:0032868]; response to sucrose [GO:0009744]; response to zinc ion [GO:0010043] GO:0004454; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006000; GO:0006001; GO:0009744; GO:0009749; GO:0009750; GO:0010043; GO:0016052; GO:0032868; GO:0046835; GO:0061624; GO:0070873 35983 XM_029339426.2 313 275 242 439 372 Q7T163 0 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 35984 XM_029339426.2 313 275 242 439 372 Q7T163 3.43e-42 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 35985 XM_029339426.2 313 275 242 439 372 Q7T163 3.59e-33 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 35986 XM_029339426.2 313 275 242 439 372 Q7T163 2.12e-29 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 35987 XM_029339426.2 313 275 242 439 372 Q7T163 5.65e-27 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 35988 XM_029339426.2 313 275 242 439 372 Q7T163 1.19e-22 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 35989 XM_044323423.1 38 16 23 36 80 NA NA NA NA NA NA 35990 XR_006391305.1 3 9 10 3 8 NA NA NA NA NA NA 35991 XM_029327388.2 2771 2059 1328 2048 386 Q8C033 1.02e-138 Rho guanine nucleotide exchange factor 10 Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; activation of GTPase activity [GO:0090630]; centrosome duplication [GO:0051298]; mitotic spindle assembly [GO:0090307]; myelination in peripheral nervous system [GO:0022011]; positive regulation of stress fiber assembly [GO:0051496] GO:0005085; GO:0005813; GO:0019894; GO:0022011; GO:0030036; GO:0051298; GO:0051496; GO:0090307; GO:0090630 35992 XM_044312937.1 7 29 7 11 9 P59046 4.04e-37 NACHT, LRR and PYD domains-containing protein 12 (Monarch-1) (PYRIN-containing APAF1-like protein 7) (Regulated by nitric oxide) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cellular response to cytokine stimulus [GO:0071345]; dendritic cell migration [GO:0036336]; ERK1 and ERK2 cascade [GO:0070371]; negative regulation of cytokine production [GO:0001818]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of signal transduction [GO:0009968]; negative regulation of Toll signaling pathway [GO:0045751]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of inflammatory response [GO:0050727]; regulation of interleukin-18 production [GO:0032661]; signal transduction [GO:0007165] GO:0001818; GO:0005524; GO:0005737; GO:0005829; GO:0006919; GO:0007165; GO:0008656; GO:0009968; GO:0031953; GO:0032088; GO:0032661; GO:0032692; GO:0032715; GO:0032731; GO:0036336; GO:0038061; GO:0043122; GO:0043124; GO:0043281; GO:0045345; GO:0045751; GO:0050727; GO:0050728; GO:0050729; GO:0070371; GO:0070373; GO:0071345; GO:1901223; GO:1901224 35993 XM_044323417.1 0 16 0 7 11 A7RWD2 9.31e-115 Probable cytosolic iron-sulfur protein assembly protein CIAO1 homolog Nematostella vectensis (Starlet sea anemone) iron-sulfur cluster assembly [GO:0016226] GO:0016226; GO:0097361 35994 XM_044323417.1 0 16 0 7 11 A7RWD2 9.82e-23 Probable cytosolic iron-sulfur protein assembly protein CIAO1 homolog Nematostella vectensis (Starlet sea anemone) iron-sulfur cluster assembly [GO:0016226] GO:0016226; GO:0097361 35995 XM_044321413.1 260 156 183 264 242 Q96AY4 3.23e-81 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35996 XM_044321413.1 260 156 183 264 242 Q96AY4 2.12e-78 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35997 XM_044321413.1 260 156 183 264 242 Q96AY4 6e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35998 XM_044321413.1 260 156 183 264 242 Q96AY4 2.2e-72 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35999 XM_044321413.1 260 156 183 264 242 Q96AY4 2.66e-72 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36000 XM_044321413.1 260 156 183 264 242 Q96AY4 2.53e-71 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36001 XM_044321413.1 260 156 183 264 242 Q96AY4 6.44e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36002 XM_044321413.1 260 156 183 264 242 Q96AY4 3.06e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36003 XM_044321413.1 260 156 183 264 242 Q96AY4 3.84e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36004 XM_029355514.2 0 35 13 87 10 Q90481 1.59e-34 Homeobox protein Nkx-2.2a (Homeobox protein NK-2 homolog B-A) Danio rerio (Zebrafish) (Brachydanio rerio) cell differentiation [GO:0030154]; endocrine pancreas development [GO:0031018]; floor plate development [GO:0033504]; floor plate formation [GO:0021508]; glial cell migration [GO:0008347]; motor neuron axon guidance [GO:0008045]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357]; Schwann cell development [GO:0014044]; spinal cord oligodendrocyte cell differentiation [GO:0021529]; spinal cord oligodendrocyte cell fate specification [GO:0021530]; ventral spinal cord interneuron differentiation [GO:0021514] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0008045; GO:0008347; GO:0014044; GO:0021508; GO:0021514; GO:0021529; GO:0021530; GO:0030154; GO:0031018; GO:0033504; GO:0045893 36005 XM_029345927.2 1207 949 1095 909 1187 Q9V3H2 0 26S proteasome non-ATPase regulatory subunit 14 (EC 3.4.19.-) (26S proteasome regulatory complex subunit p37B) (26S proteasome regulatory subunit rpn11) (Yippee-interacting protein 5) Drosophila melanogaster (Fruit fly) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579] GO:0000502; GO:0005654; GO:0005829; GO:0005838; GO:0008237; GO:0008541; GO:0016579; GO:0043161; GO:0046872; GO:0070628; GO:0140492 36006 XM_029342418.2 0 0 255 0 696 P16157 3.31e-94 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 36007 XM_029342418.2 0 0 255 0 696 P16157 1.89e-86 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 36008 XM_029342418.2 0 0 255 0 696 P16157 5.04e-86 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 36009 XM_029342418.2 0 0 255 0 696 P16157 1.07e-55 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 36010 XM_029342418.2 0 0 255 0 696 P16157 2.02e-34 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 36011 XM_029342418.2 0 0 255 0 696 P16157 1.55e-24 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 36012 XM_029333852.2 992 86 159 507 0 Q8K4J6 3.39e-26 Myocardin-related transcription factor A (MRTF-A) (Basic SAP coiled-coil transcription activator) (MKL/myocardin-like protein 1) (Megakaryoblastic leukemia 1 protein homolog) (Megakaryocytic acute leukemia protein homolog) Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; forebrain development [GO:0030900]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; smooth muscle cell differentiation [GO:0051145]; wound healing, spreading of cells [GO:0044319] GO:0000976; GO:0001764; GO:0003700; GO:0003713; GO:0003779; GO:0003785; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006357; GO:0030036; GO:0030900; GO:0031175; GO:0043154; GO:0043522; GO:0044319; GO:0045893; GO:0045944; GO:0051145; GO:0060090; GO:1902895; GO:2001234 36013 XM_029336417.2 204 161 176 46 174 NA NA NA NA NA NA 36014 XM_044312724.1 4 3 0 2 8 NA NA NA NA NA NA 36015 XM_029334957.2 1558 2156 1072 1351 1933 O35207 1.61e-22 Cyclin-dependent kinase 2-associated protein 1 (CDK2-associated protein 1) (Deleted in oral cancer 1) (DOC-1) (Putative oral cancer suppressor) Mus musculus (Mouse) cell cycle [GO:0007049]; face morphogenesis [GO:0060325]; in utero embryonic development [GO:0001701]; positive regulation of protein phosphorylation [GO:0001934] GO:0001701; GO:0001934; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0007049; GO:0048471; GO:0060325; GO:0070182 36016 XM_044306933.1 0 12 0 0 0 NA NA NA NA NA NA 36017 XM_044329274.1 8 0 1 0 11 Q7L622 1.22e-31 G2/M phase-specific E3 ubiquitin-protein ligase (EC 2.3.2.26) (G2/M phase-specific HECT-type E3 ubiquitin transferase) Homo sapiens (Human) apoptotic process [GO:0006915] GO:0004842; GO:0005634; GO:0005730; GO:0005794; GO:0005829; GO:0006915; GO:0043231; GO:0046872 36018 XM_029339005.2 28 32 33 44 54 A6NJI9 2.5e-21 Leucine-rich repeat-containing protein 72 Homo sapiens (Human) NA NA 36019 XR_006392554.1 23 7 22 18 10 NA NA NA NA NA NA 36020 XM_029326560.2 52 94 65 26 31 NA NA NA NA NA NA 36021 XM_044320232.1 669 596 322 462 598 Q9VXB5 1.73e-31 39S ribosomal protein L22, mitochondrial (L22mt) (MRP-L22) Drosophila melanogaster (Fruit fly) mitochondrial translation [GO:0032543]; ribosome assembly [GO:0042255] GO:0003735; GO:0005739; GO:0005762; GO:0015934; GO:0032543; GO:0042255 36022 XM_029349991.2 13 4 31 21 73 NA NA NA NA NA NA 36023 XM_044321102.1 0 243 381 0 0 NA NA NA NA NA NA 36024 XM_029324415.2 1915 1513 905 1649 1683 Q91WA9 0 ATP-binding cassette subfamily G member 4 (EC 7.6.2.-) (ATP-binding cassette transporter White2) Mus musculus (Mouse) cellular response to high density lipoprotein particle stimulus [GO:0071403]; cellular response to leukemia inhibitory factor [GO:1990830]; cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of cholesterol efflux [GO:0010875]; regulation of DNA-templated transcription [GO:0006355]; sterol transport [GO:0015918]; transmembrane transport [GO:0055085] GO:0005524; GO:0005768; GO:0005886; GO:0006355; GO:0010008; GO:0010875; GO:0015918; GO:0016020; GO:0016887; GO:0031410; GO:0033344; GO:0034041; GO:0042626; GO:0042632; GO:0042802; GO:0042803; GO:0045542; GO:0046982; GO:0055085; GO:0071403; GO:1990830 36025 XM_044308256.1 57 27 25 49 49 O93403 2.9e-25 Carbohydrate sulfotransferase 3 (EC 2.8.2.17) (EC 2.8.2.21) (Chondroitin 6-O-sulfotransferase 1) (C6ST-1) (Nervous system involved sulfotransferase) Tetronarce californica (Pacific electric ray) (Torpedo californica) carbohydrate metabolic process [GO:0005975]; chondroitin sulfate biosynthetic process [GO:0030206] GO:0000139; GO:0005975; GO:0008459; GO:0030206 36026 XM_044319809.1 61 0 23 0 0 P97292 4.4e-21 Histamine H2 receptor (H2R) (HH2R) (Gastric receptor I) Mus musculus (Mouse) chemical synaptic transmission [GO:0007268]; digestive tract development [GO:0048565]; epithelial cell morphogenesis [GO:0003382]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; gastric acid secretion [GO:0001696]; gastrin-induced gastric acid secretion [GO:0001698]; gland development [GO:0048732]; histamine-induced gastric acid secretion [GO:0001697]; memory [GO:0007613]; negative regulation of arachidonic acid secretion [GO:1900139]; positive regulation of vasoconstriction [GO:0045907]; regulation of synaptic plasticity [GO:0048167]; toxin transport [GO:1901998]; visual learning [GO:0008542] GO:0001696; GO:0001697; GO:0001698; GO:0003382; GO:0004969; GO:0004993; GO:0005886; GO:0007187; GO:0007268; GO:0007613; GO:0008542; GO:0016020; GO:0030425; GO:0030594; GO:0045202; GO:0045907; GO:0048167; GO:0048565; GO:0048732; GO:1900139; GO:1901363; GO:1901998 36027 XM_044312244.1 45 12 66 103 24 Q6PEC4 9.02e-54 S-phase kinase-associated protein 1 (Cyclin-A/CDK2-associated protein p19) (S-phase kinase-associated protein 1A) (p19A) (p19skp1) Rattus norvegicus (Rat) chromatin remodeling [GO:0006338]; histone H2A monoubiquitination [GO:0035518]; maintenance of protein location in nucleus [GO:0051457]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; protein K48-linked ubiquitination [GO:0070936]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0000209; GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0005921; GO:0006338; GO:0006513; GO:0008013; GO:0016567; GO:0019005; GO:0019904; GO:0031146; GO:0031467; GO:0031519; GO:0035518; GO:0051457; GO:0070936; GO:0097602; GO:1904668; GO:1990444; GO:1990756 36028 XM_029342051.2 659 522 302 543 565 S3D784 3.79e-36 2-oxoglutarate-dependent dioxygenase gloF (EC 1.14.-.-) (Pneumocandin biosynthesis cluster protein F) (Proline hydroxylase) Glarea lozoyensis (strain ATCC 20868 / MF5171) organic acid biosynthetic process [GO:0016053]; organic cyclic compound biosynthetic process [GO:1901362] GO:0016053; GO:0046872; GO:0051213; GO:1901362 36029 XM_029347754.2 61 1 24 0 29 NA NA NA NA NA NA 36030 XM_044318369.1 2 0 2 3 20 NA NA NA NA NA NA 36031 XM_029358579.2 4550 3302 3212 4336 3126 Q3SZV6 1.02e-33 Mitochondrial import inner membrane translocase subunit Tim21 (TIM21-like protein, mitochondrial) Bos taurus (Bovine) mitochondrial cytochrome c oxidase assembly [GO:0033617]; mitochondrial respiratory chain complex I assembly [GO:0032981]; protein import into mitochondrial matrix [GO:0030150] GO:0005744; GO:0030150; GO:0032981; GO:0033617 36032 XM_044313481.1 9 2 0 0 1 P07911 7.42e-50 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Homo sapiens (Human) antibacterial innate immune response [GO:0140367]; apoptotic signaling pathway [GO:0097190]; autophagy [GO:0006914]; cellular calcium ion homeostasis [GO:0006874]; cellular chloride ion homeostasis [GO:0030644]; cellular defense response [GO:0006968]; cellular phosphate ion homeostasis [GO:0030643]; cellular response to unfolded protein [GO:0034620]; cellular sodium ion homeostasis [GO:0006883]; chaperone-mediated protein folding [GO:0061077]; citric acid secretion [GO:0046720]; collecting duct development [GO:0072044]; connective tissue replacement [GO:0097709]; creatinine homeostasis [GO:0097273]; defense response to Gram-negative bacterium [GO:0050829]; endoplasmic reticulum organization [GO:0007029]; glomerular filtration [GO:0003094]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; juxtaglomerular apparatus development [GO:0072051]; leukocyte cell-cell adhesion [GO:0007159]; lipid metabolic process [GO:0006629]; metanephric ascending thin limb development [GO:0072218]; metanephric distal convoluted tubule development [GO:0072221]; metanephric thick ascending limb development [GO:0072233]; micturition [GO:0060073]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell population proliferation [GO:0008285]; neutrophil migration [GO:1990266]; organ or tissue specific immune response [GO:0002251]; peptidyl-threonine phosphorylation [GO:0018107]; potassium ion homeostasis [GO:0055075]; protein localization to vacuole [GO:0072665]; protein transport into plasma membrane raft [GO:0044861]; regulation of blood pressure [GO:0008217]; regulation of protein transport [GO:0051223]; regulation of urine volume [GO:0035809]; renal sodium ion absorption [GO:0070294]; renal urate salt excretion [GO:0097744]; renal water homeostasis [GO:0003091]; response to lipopolysaccharide [GO:0032496]; response to water deprivation [GO:0009414]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; ubiquitin-dependent ERAD pathway [GO:0030433]; urate transport [GO:0015747]; urea transmembrane transport [GO:0071918] GO:0000922; GO:0002251; GO:0003091; GO:0003094; GO:0005201; GO:0005509; GO:0005615; GO:0005783; GO:0005796; GO:0005929; GO:0006629; GO:0006874; GO:0006883; GO:0006914; GO:0006954; GO:0006968; GO:0007029; GO:0007157; GO:0007159; GO:0008217; GO:0008285; GO:0008380; GO:0009410; GO:0009414; GO:0009986; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0018107; GO:0019864; GO:0019898; GO:0030433; GO:0030643; GO:0030644; GO:0032496; GO:0033209; GO:0033555; GO:0034620; GO:0035809; GO:0044861; GO:0046720; GO:0050829; GO:0051223; GO:0055075; GO:0060073; GO:0060170; GO:0061077; GO:0070062; GO:0070294; GO:0071918; GO:0072044; GO:0072051; GO:0072218; GO:0072221; GO:0072233; GO:0072665; GO:0097190; GO:0097273; GO:0097709; GO:0097744; GO:0140367; GO:1990266 36033 XM_044313481.1 9 2 0 0 1 P07911 5.09e-23 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Homo sapiens (Human) antibacterial innate immune response [GO:0140367]; apoptotic signaling pathway [GO:0097190]; autophagy [GO:0006914]; cellular calcium ion homeostasis [GO:0006874]; cellular chloride ion homeostasis [GO:0030644]; cellular defense response [GO:0006968]; cellular phosphate ion homeostasis [GO:0030643]; cellular response to unfolded protein [GO:0034620]; cellular sodium ion homeostasis [GO:0006883]; chaperone-mediated protein folding [GO:0061077]; citric acid secretion [GO:0046720]; collecting duct development [GO:0072044]; connective tissue replacement [GO:0097709]; creatinine homeostasis [GO:0097273]; defense response to Gram-negative bacterium [GO:0050829]; endoplasmic reticulum organization [GO:0007029]; glomerular filtration [GO:0003094]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; juxtaglomerular apparatus development [GO:0072051]; leukocyte cell-cell adhesion [GO:0007159]; lipid metabolic process [GO:0006629]; metanephric ascending thin limb development [GO:0072218]; metanephric distal convoluted tubule development [GO:0072221]; metanephric thick ascending limb development [GO:0072233]; micturition [GO:0060073]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell population proliferation [GO:0008285]; neutrophil migration [GO:1990266]; organ or tissue specific immune response [GO:0002251]; peptidyl-threonine phosphorylation [GO:0018107]; potassium ion homeostasis [GO:0055075]; protein localization to vacuole [GO:0072665]; protein transport into plasma membrane raft [GO:0044861]; regulation of blood pressure [GO:0008217]; regulation of protein transport [GO:0051223]; regulation of urine volume [GO:0035809]; renal sodium ion absorption [GO:0070294]; renal urate salt excretion [GO:0097744]; renal water homeostasis [GO:0003091]; response to lipopolysaccharide [GO:0032496]; response to water deprivation [GO:0009414]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; ubiquitin-dependent ERAD pathway [GO:0030433]; urate transport [GO:0015747]; urea transmembrane transport [GO:0071918] GO:0000922; GO:0002251; GO:0003091; GO:0003094; GO:0005201; GO:0005509; GO:0005615; GO:0005783; GO:0005796; GO:0005929; GO:0006629; GO:0006874; GO:0006883; GO:0006914; GO:0006954; GO:0006968; GO:0007029; GO:0007157; GO:0007159; GO:0008217; GO:0008285; GO:0008380; GO:0009410; GO:0009414; GO:0009986; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0018107; GO:0019864; GO:0019898; GO:0030433; GO:0030643; GO:0030644; GO:0032496; GO:0033209; GO:0033555; GO:0034620; GO:0035809; GO:0044861; GO:0046720; GO:0050829; GO:0051223; GO:0055075; GO:0060073; GO:0060170; GO:0061077; GO:0070062; GO:0070294; GO:0071918; GO:0072044; GO:0072051; GO:0072218; GO:0072221; GO:0072233; GO:0072665; GO:0097190; GO:0097273; GO:0097709; GO:0097744; GO:0140367; GO:1990266 36034 XM_044307063.1 31 7 14 37 16 Q40723 4.35e-27 Ras-related protein RGP2 (GTP-binding regulatory protein RGP2) Oryza sativa subsp. japonica (Rice) NA GO:0003924; GO:0005525; GO:0005768; GO:0005794; GO:0005886 36035 XM_029342597.2 107 144 186 177 306 NA NA NA NA NA NA 36036 XR_003828419.2 716 1173 616 514 301 NA NA NA NA NA NA 36037 XM_044317982.1 0 0 5 0 19 NA NA NA NA NA NA 36038 XM_029330466.2 120 247 78 191 145 Q708S6 5.35e-49 Acid-sensing ion channel 1C (ASIC1-C) (Acid-sensing ion channel 1.3-C) (Amiloride-sensitive cation channel 2-C, neuronal-C) (ZASIC1.3) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to pH [GO:0071467]; protein homotrimerization [GO:0070207]; sodium ion transmembrane transport [GO:0035725] GO:0005261; GO:0005886; GO:0015280; GO:0035725; GO:0044736; GO:0070207; GO:0071467 36039 XR_006395754.1 24 0 0 8 6 NA NA NA NA NA NA 36040 XR_006392261.1 6 0 0 0 0 NA NA NA NA NA NA 36041 XM_029338682.2 482 244 161 246 341 Q9GZN2 2.51e-33 Homeobox protein TGIF2 (5'-TG-3'-interacting factor 2) (TGF-beta-induced transcription factor 2) (TGFB-induced factor 2) Homo sapiens (Human) amacrine cell differentiation [GO:0035881]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nodal signaling pathway [GO:0038092]; positive regulation of amacrine cell differentiation [GO:1902871]; regulation of DNA-templated transcription [GO:0006355]; regulation of gastrulation [GO:0010470]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000785; GO:0000978; GO:0000981; GO:0003700; GO:0005634; GO:0005654; GO:0005813; GO:0006355; GO:0006357; GO:0010470; GO:0035881; GO:0038092; GO:1902871; GO:1990837 36042 XM_044315093.1 509 283 325 638 582 Q8BH74 0 Nuclear pore complex protein Nup107 (107 kDa nucleoporin) (Nucleoporin Nup107) Mus musculus (Mouse) female gonad development [GO:0008585]; mRNA export from nucleus [GO:0006406]; nephron development [GO:0072006]; nuclear pore complex assembly [GO:0051292]; nucleocytoplasmic transport [GO:0006913]; post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000973]; protein import into nucleus [GO:0006606] GO:0000776; GO:0000973; GO:0005635; GO:0005643; GO:0006406; GO:0006606; GO:0006913; GO:0008585; GO:0017056; GO:0031080; GO:0031965; GO:0034399; GO:0051292; GO:0072006 36043 XM_029341960.2 0 0 0 113 708 P98070 5.14e-21 Bone morphogenetic protein 1 (BMP-1) (EC 3.4.24.-) Xenopus laevis (African clawed frog) cartilage development [GO:0051216]; cell differentiation [GO:0030154]; ossification [GO:0001503]; proteolysis [GO:0006508] GO:0001503; GO:0004222; GO:0005125; GO:0005509; GO:0005615; GO:0005794; GO:0006508; GO:0008083; GO:0008270; GO:0030154; GO:0051216 36044 XM_029356173.2 555 29 33 190 224 NA NA NA NA NA NA 36045 XM_044313137.1 232 55 144 174 157 NA NA NA NA NA NA 36046 XR_006392844.1 6 1 6 0 13 NA NA NA NA NA NA 36047 XM_029340670.2 1776 1375 1226 1772 2126 O14795 0 Protein unc-13 homolog B (Munc13-2) (munc13) Homo sapiens (Human) acrosomal vesicle exocytosis [GO:0060478]; cellular response to glucose stimulus [GO:0071333]; chemical synaptic transmission [GO:0007268]; dense core granule priming [GO:0061789]; neuromuscular junction development [GO:0007528]; neuronal dense core vesicle exocytosis [GO:0099011]; positive regulation of apoptotic process [GO:0043065]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of protein secretion [GO:0050714]; positive regulation of synaptic vesicle priming [GO:0010808]; presynaptic dense core vesicle exocytosis [GO:0099525]; synaptic transmission, glutamatergic [GO:0035249]; synaptic vesicle docking [GO:0016081]; synaptic vesicle maturation [GO:0016188]; synaptic vesicle priming [GO:0016082] GO:0005509; GO:0005516; GO:0005543; GO:0005794; GO:0005829; GO:0005886; GO:0007268; GO:0007528; GO:0010808; GO:0016020; GO:0016081; GO:0016082; GO:0016188; GO:0017075; GO:0019992; GO:0030672; GO:0030742; GO:0031267; GO:0031594; GO:0035249; GO:0042734; GO:0043065; GO:0043195; GO:0048786; GO:0050714; GO:0060478; GO:0061789; GO:0071333; GO:0097151; GO:0098831; GO:0099011; GO:0099525 36048 XM_029333839.2 52 149 140 465 637 NA NA NA NA NA NA 36049 XM_044310368.1 0 0 0 14 15 NA NA NA NA NA NA 36050 XM_029330654.2 832 542 385 578 407 B5FXE5 3.43e-65 Ferroptosis suppressor protein 1 (FSP1) (EC 1.6.5.-) (Apoptosis-inducing factor homologous mitochondrion-associated inducer of death) (AMID) (p53-responsive gene 3 protein) Taeniopygia guttata (Zebra finch) (Poephila guttata) apoptotic process [GO:0006915]; vitamin K metabolic process [GO:0042373] GO:0005634; GO:0005811; GO:0005886; GO:0006915; GO:0016655; GO:0031966; GO:0042373 36051 XR_003827481.2 32 0 28 31 0 NA NA NA NA NA NA 36052 XM_029341996.2 343 170 168 483 418 Q5NVD0 0 U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0005681; GO:0006397; GO:0008380; GO:0016607; GO:0071001; GO:0097525 36053 XR_006395721.1 45028 46725 18814 33404 18431 NA NA NA NA NA NA 36054 XM_044314182.1 3 0 0 17 32 NA NA NA NA NA NA 36055 XM_044325158.1 44 20 28 41 48 NA NA NA NA NA NA 36056 XM_044311998.1 41 6 42 11 96 NA NA NA NA NA NA 36057 XM_029329673.2 200 246 117 233 148 NA NA NA NA NA NA 36058 XR_003824013.2 18 0 0 8 12 NA NA NA NA NA NA 36059 XM_029337883.2 11 50 2 22 0 NA NA NA NA NA NA 36060 XM_044325765.1 24 7 5 8 3 NA NA NA NA NA NA 36061 XM_044318317.1 0 1 11 12 0 Q99315 3.97e-65 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 36062 XM_044322380.1 411 229 199 214 449 Q60HE5 0 Methylenetetrahydrofolate reductase (NADPH) (EC 1.5.1.53) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) methionine metabolic process [GO:0006555]; tetrahydrofolate interconversion [GO:0035999] GO:0004489; GO:0006555; GO:0035999; GO:0106313 36063 XM_029351833.2 131 48 0 450 91 P23508 3.86e-95 Colorectal mutant cancer protein (Protein MCC) Homo sapiens (Human) establishment of protein localization [GO:0045184]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of epithelial cell proliferation [GO:0050680]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055] GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0007165; GO:0010633; GO:0016055; GO:0030027; GO:0036464; GO:0038023; GO:0045184; GO:0050680; GO:0090090 36064 XM_029325742.2 2066 1714 1398 1443 827 Q28BQ6 2.97e-28 Transmembrane emp24 domain-containing protein 1 (p24 family protein gamma-1) (p24gamma1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) protein transport [GO:0015031] GO:0005789; GO:0005794; GO:0005886; GO:0015031; GO:0033116 36065 XM_044318673.1 0 0 0 0 23 NA NA NA NA NA NA 36066 XM_029331755.2 405 148 334 512 180 NA NA NA NA NA NA 36067 XR_006397912.1 0 51 0 87 68 NA NA NA NA NA NA 36068 XM_029352831.2 134 197 89 135 164 NA NA NA NA NA NA 36069 XM_044317335.1 814 1943 334 1812 881 NA NA NA NA NA NA 36070 XM_044310084.1 121 138 56 104 101 Q14585 2.39e-130 Zinc finger protein 345 (Zinc finger protein HZF10) Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription by RNA polymerase III [GO:0006359]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383] GO:0000122; GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0006359; GO:0006366; GO:0006383; GO:0046872; GO:1990837 36071 XM_044310084.1 121 138 56 104 101 Q14585 6.42e-128 Zinc finger protein 345 (Zinc finger protein HZF10) Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription by RNA polymerase III [GO:0006359]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383] GO:0000122; GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0006359; GO:0006366; GO:0006383; GO:0046872; GO:1990837 36072 XM_044310084.1 121 138 56 104 101 Q14585 5.15e-123 Zinc finger protein 345 (Zinc finger protein HZF10) Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription by RNA polymerase III [GO:0006359]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383] GO:0000122; GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0006359; GO:0006366; GO:0006383; GO:0046872; GO:1990837 36073 XM_044310084.1 121 138 56 104 101 Q14585 2.75e-96 Zinc finger protein 345 (Zinc finger protein HZF10) Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription by RNA polymerase III [GO:0006359]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383] GO:0000122; GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0006359; GO:0006366; GO:0006383; GO:0046872; GO:1990837 36074 XM_029330628.2 2 0 0 7 37 NA NA NA NA NA NA 36075 XR_006396742.1 28 75 18 15 22 NA NA NA NA NA NA 36076 XM_029333513.2 1965 2166 1598 3652 4146 Q9BXW4 2.47e-52 Microtubule-associated proteins 1A/1B light chain 3C (Autophagy-related protein LC3 C) (Autophagy-related ubiquitin-like modifier LC3 C) (MAP1 light chain 3-like protein 3) (MAP1A/MAP1B light chain 3 C) (MAP1A/MAP1B LC3 C) (Microtubule-associated protein 1 light chain 3 gamma) Homo sapiens (Human) aggrephagy [GO:0035973]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]; protein exit from endoplasmic reticulum [GO:0032527] GO:0000045; GO:0000421; GO:0000422; GO:0005776; GO:0005829; GO:0005874; GO:0006995; GO:0008017; GO:0009267; GO:0012505; GO:0016236; GO:0031090; GO:0031410; GO:0031625; GO:0032527; GO:0035973; GO:0036464; GO:0097352 36077 XM_044325644.1 20 0 34 48 18 A7SCH8 4.74e-151 Kynureninase (EC 3.7.1.3) (L-kynurenine hydrolase) Nematostella vectensis (Starlet sea anemone) 'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; anthranilate metabolic process [GO:0043420]; L-kynurenine catabolic process [GO:0097053]; quinolinate biosynthetic process [GO:0019805]; tryptophan catabolic process to kynurenine [GO:0019441] GO:0005737; GO:0019441; GO:0019805; GO:0030170; GO:0030429; GO:0034354; GO:0043420; GO:0061981; GO:0097053 36078 XM_044310394.1 1859 1068 953 1684 1317 O95622 0 Adenylate cyclase type 5 (EC 4.6.1.1) (ATP pyrophosphate-lyase 5) (Adenylate cyclase type V) (Adenylyl cyclase 5) (AC5) Homo sapiens (Human) adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; cAMP biosynthetic process [GO:0006171]; cellular response to forskolin [GO:1904322]; G protein-coupled adenosine receptor signaling pathway [GO:0001973]; intracellular signal transduction [GO:0035556]; locomotory behavior [GO:0007626]; neuromuscular process controlling balance [GO:0050885]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178] GO:0001973; GO:0004016; GO:0005524; GO:0005886; GO:0005929; GO:0006171; GO:0007189; GO:0007191; GO:0007193; GO:0007195; GO:0007204; GO:0007626; GO:0008179; GO:0016020; GO:0035556; GO:0045111; GO:0046872; GO:0050885; GO:0061178; GO:0097110; GO:1904322 36079 XM_029328790.2 0 9 43 0 0 Q8R2J9 4.9e-116 DNA repair protein RAD51 homolog 3 (R51H3) (RAD51 homolog C) (RAD51-like protein 2) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) DNA recombination [GO:0006310]; DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; female meiosis sister chromatid cohesion [GO:0007066]; male meiosis I [GO:0007141]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; reciprocal meiotic recombination [GO:0007131]; sister chromatid cohesion [GO:0007062]; spermatogenesis [GO:0007283]; telomere maintenance via recombination [GO:0000722] GO:0000400; GO:0000722; GO:0000724; GO:0005524; GO:0005634; GO:0005654; GO:0005657; GO:0005737; GO:0005739; GO:0005829; GO:0006281; GO:0006310; GO:0007062; GO:0007066; GO:0007131; GO:0007141; GO:0007283; GO:0008821; GO:0010971; GO:0030054; GO:0033063; GO:0033065; GO:0048471; GO:0048476; GO:0140664 36080 XM_029333770.2 379 312 177 216 200 NA NA NA NA NA NA 36081 XR_006393152.1 34 11 53 28 59 NA NA NA NA NA NA 36082 XM_044309784.1 1 19 1 5 32 NA NA NA NA NA NA 36083 XM_044308124.1 0 0 0 50 0 Q6P8Y1 4.34e-71 Calcyphosin-like protein Mus musculus (Mouse) NA GO:0005509; GO:0005737 36084 XM_044316758.1 490 550 340 644 283 NA NA NA NA NA NA 36085 XR_006391889.1 17 0 1 48 6 NA NA NA NA NA NA 36086 XM_044320918.1 23 0 0 13 0 Q9VBW3 1.58e-61 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 36087 XM_029352523.2 351 224 124 55 235 Q9P2K3 7.21e-112 REST corepressor 3 Homo sapiens (Human) histone deacetylation [GO:0016575]; negative regulation of DNA-templated transcription [GO:0045892]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000118; GO:0003714; GO:0005654; GO:0005667; GO:0005829; GO:0006357; GO:0016575; GO:0045892 36088 XM_044308967.1 0 0 0 8 0 NA NA NA NA NA NA 36089 XM_044308775.1 20 29 7 5 18 NA NA NA NA NA NA 36090 XM_044319684.1 386 1882 1104 1102 640 Q8WNV7 8.15e-83 Dehydrogenase/reductase SDR family member 4 (EC 1.1.1.184) (EC 1.1.1.300) (NADPH-dependent carbonyl reductase) (CR) (PHCR) (NADPH-dependent retinol dehydrogenase/reductase) (NDRD) (Peroxisomal carbonyl reductase) (PerCR) (Peroxisomal short-chain alcohol dehydrogenase) (PSCD) (Short chain dehydrogenase/reductase family 25C member 2) (Protein SDR25C2) Sus scrofa (Pig) cellular ketone metabolic process [GO:0042180]; retinal metabolic process [GO:0042574]; retinoid metabolic process [GO:0001523]; steroid metabolic process [GO:0008202] GO:0000253; GO:0001523; GO:0004090; GO:0005739; GO:0005777; GO:0008202; GO:0042180; GO:0042574; GO:0042802; GO:0052650 36091 XM_044322351.1 79 0 25 19 34 P06845 3.56e-22 Tyrosinase (EC 1.14.18.1) (Monophenol monooxygenase) Streptomyces glaucescens melanin biosynthetic process [GO:0042438] GO:0004503; GO:0042438; GO:0046872 36092 XM_044314363.1 0 7 0 0 0 NA NA NA NA NA NA 36093 XM_044308995.1 15 312 0 151 104 NA NA NA NA NA NA 36094 XM_044312387.1 33 0 0 0 5 A6NED2 1.29e-39 RCC1 domain-containing protein 1 Homo sapiens (Human) chromatin organization [GO:0006325] GO:0005694; GO:0005829; GO:0005886; GO:0006325 36095 XM_029335790.2 828 256 410 621 943 P43249 0 G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK5) Bos taurus (Bovine) apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell population proliferation [GO:0008284]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell cycle [GO:0051726]; regulation of signal transduction [GO:0009966]; tachykinin receptor signaling pathway [GO:0007217]; Wnt signaling pathway [GO:0016055] GO:0004672; GO:0004674; GO:0004703; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006468; GO:0006915; GO:0007217; GO:0008284; GO:0008289; GO:0009966; GO:0016055; GO:0016607; GO:0031965; GO:0043066; GO:0046777; GO:0047696; GO:0051726 36096 XR_003824072.2 14 31 16 15 8 A1L1W9 9.53e-45 Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10) Danio rerio (Zebrafish) (Brachydanio rerio) aromatic amino acid transport [GO:0015801]; thyroid hormone transport [GO:0070327] GO:0005302; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0070327 36097 XM_044310331.1 5 8 2 0 9 NA NA NA NA NA NA 36098 XM_044311810.1 90 13 21 100 7 Q96AY4 3.86e-102 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36099 XM_044311810.1 90 13 21 100 7 Q96AY4 1.52e-101 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36100 XM_044311810.1 90 13 21 100 7 Q96AY4 5.09e-101 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36101 XM_044311810.1 90 13 21 100 7 Q96AY4 2.11e-100 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36102 XM_044311810.1 90 13 21 100 7 Q96AY4 2.27e-100 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36103 XM_044311810.1 90 13 21 100 7 Q96AY4 2.85e-99 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36104 XM_044311810.1 90 13 21 100 7 Q96AY4 7.43e-50 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36105 XM_044311810.1 90 13 21 100 7 Q96AY4 4.39e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36106 XM_044311810.1 90 13 21 100 7 Q96AY4 2.54e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36107 XM_044308848.1 101 117 123 335 639 P09917 3.74e-41 Polyunsaturated fatty acid 5-lipoxygenase (EC 1.13.11.-) (Arachidonate 5-lipoxygenase) (5-LO) (5-lipoxygenase) (EC 1.13.11.34) Homo sapiens (Human) arachidonic acid metabolic process [GO:0019369]; dendritic cell migration [GO:0036336]; glucose homeostasis [GO:0042593]; hepoxilin biosynthetic process [GO:0051122]; humoral immune response [GO:0006959]; leukocyte chemotaxis involved in inflammatory response [GO:0002232]; leukocyte migration involved in inflammatory response [GO:0002523]; leukotriene A4 biosynthetic process [GO:1901753]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; leukotriene production involved in inflammatory response [GO:0002540]; linoleic acid metabolic process [GO:0043651]; lipid oxidation [GO:0034440]; lipoxin biosynthetic process [GO:2001301]; lipoxygenase pathway [GO:0019372]; long-chain fatty acid biosynthetic process [GO:0042759]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of inflammatory response [GO:0050728]; negative regulation of response to endoplasmic reticulum stress [GO:1903573]; negative regulation of sprouting angiogenesis [GO:1903671]; negative regulation of vascular wound healing [GO:0061044]; negative regulation of wound healing [GO:0061045]; positive regulation of bone mineralization [GO:0030501]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; regulation of cellular response to oxidative stress [GO:1900407]; regulation of cytokine production involved in inflammatory response [GO:1900015]; regulation of fat cell differentiation [GO:0045598]; regulation of inflammatory response [GO:0050727]; regulation of inflammatory response to wounding [GO:0106014]; regulation of insulin secretion [GO:0050796]; regulation of reactive oxygen species biosynthetic process [GO:1903426] GO:0001937; GO:0002232; GO:0002523; GO:0002540; GO:0004051; GO:0004052; GO:0005506; GO:0005576; GO:0005615; GO:0005635; GO:0005641; GO:0005654; GO:0005829; GO:0006691; GO:0006959; GO:0016363; GO:0016525; GO:0016702; GO:0016787; GO:0019369; GO:0019370; GO:0019372; GO:0030501; GO:0031965; GO:0034440; GO:0034774; GO:0036336; GO:0036403; GO:0042593; GO:0042759; GO:0043651; GO:0045598; GO:0048471; GO:0050727; GO:0050728; GO:0050796; GO:0051122; GO:0061044; GO:0061045; GO:0106014; GO:1900015; GO:1900407; GO:1901753; GO:1903426; GO:1903573; GO:1903671; GO:1904813; GO:1904999; GO:2001301 36108 XM_029349628.2 5474 2220 1645 1926 2058 O57321 3.85e-128 Excitatory amino acid transporter 1 (SEAAT1) (Sodium-dependent glutamate/aspartate transporter) (GLAST) Ambystoma tigrinum (Eastern tiger salamander) chloride transmembrane transport [GO:1902476]; D-aspartate import across plasma membrane [GO:0070779]; L-aspartate import across plasma membrane [GO:0140009]; L-glutamate import across plasma membrane [GO:0098712]; potassium ion transmembrane transport [GO:0071805] GO:0005314; GO:0005886; GO:0015501; GO:0046872; GO:0070779; GO:0071805; GO:0098712; GO:0140009; GO:1902476 36109 XM_029327221.2 257 46 510 465 1235 P47736 6.85e-114 Rap1 GTPase-activating protein 1 (Rap1GAP) (Rap1GAP1) Homo sapiens (Human) activation of GTPase activity [GO:0090630]; adaptive immune response [GO:0002250]; cellular response to glial cell derived neurotrophic factor [GO:1990792]; negative regulation of GTP binding [GO:1904425]; negative regulation of microvillus assembly [GO:1903697]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of thyroid gland epithelial cell proliferation [GO:1904442]; positive regulation of GTPase activity [GO:0043547]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] GO:0000139; GO:0002250; GO:0003924; GO:0005096; GO:0005737; GO:0005769; GO:0005829; GO:0007165; GO:0016020; GO:0030424; GO:0030425; GO:0031267; GO:0042803; GO:0043025; GO:0043087; GO:0043547; GO:0045665; GO:0051056; GO:0090630; GO:1903697; GO:1904425; GO:1904442; GO:1990792 36110 XM_029335118.2 10 2 1 10 2 Q96P65 2.14e-29 Pyroglutamylated RF-amide peptide receptor (AQ27) (G-protein coupled receptor 103) (Orexigenic neuropeptide QRFP receptor) (SP9155) Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:0016020 36111 XM_044327848.1 6 0 0 0 18 NA NA NA NA NA NA 36112 XM_044316029.1 23 7 8 7 54 Q54H55 3.15e-30 FAD-linked oxidoreductase DDB_G0289697 (EC 1.-.-.-) Dictyostelium discoideum (Social amoeba) NA GO:0016491; GO:0071949 36113 XR_006398092.1 24 0 0 0 18 NA NA NA NA NA NA 36114 XM_029346691.2 0 101 1 0 0 A2AUY4 3.5e-99 Bromodomain adjacent to zinc finger domain protein 2B Mus musculus (Mouse) NA GO:0003677; GO:0005634; GO:0046872 36115 XM_029346691.2 0 101 1 0 0 A2AUY4 2.79e-43 Bromodomain adjacent to zinc finger domain protein 2B Mus musculus (Mouse) NA GO:0003677; GO:0005634; GO:0046872 36116 XR_006395998.1 19 1 7 6 1 NA NA NA NA NA NA 36117 XM_029342269.2 212 215 168 161 88 P15129 1.42e-130 Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1) (Cytochrome P450 L-2) (Cytochrome P450 isozyme 5) Rattus norvegicus (Rat) biphenyl metabolic process [GO:0018879] GO:0004497; GO:0005506; GO:0005789; GO:0018879; GO:0020037; GO:0043231; GO:0070330; GO:1901363 36118 XM_029350083.2 39 21 54 157 31 NA NA NA NA NA NA 36119 XM_029350830.2 246 218 158 266 387 NA NA NA NA NA NA 36120 XM_029340196.2 899 907 553 705 955 Q3U821 1.35e-123 WD repeat-containing protein 75 (U3 small nucleolar RNA-associated protein 17 homolog) Mus musculus (Mouse) positive regulation of rRNA processing [GO:2000234]; positive regulation of transcription by RNA polymerase I [GO:0045943]; rRNA processing [GO:0006364] GO:0003723; GO:0005730; GO:0006364; GO:0045943; GO:2000234 36121 XM_029346240.2 2117 1188 777 1277 2426 NA NA NA NA NA NA 36122 XM_029328476.2 1250 1055 787 926 1149 Q5SZT7 4.45e-50 NKAP-like protein Mus musculus (Mouse) cell differentiation [GO:0030154]; regulation of gene expression [GO:0010468]; spermatogenesis [GO:0007283] GO:0003682; GO:0005634; GO:0007283; GO:0010468; GO:0030154 36123 XM_029328447.2 865 781 622 828 1054 NA NA NA NA NA NA 36124 XM_044321072.1 362 0 142 0 374 B2GUZ1 0 Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.4.19.12) (Deubiquitinating enzyme 4) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) Rattus norvegicus (Rat) negative regulation of protein ubiquitination [GO:0031397]; protein deubiquitination [GO:0016579]; protein localization to cell surface [GO:0034394]; regulation of protein stability [GO:0031647]; spliceosomal tri-snRNP complex assembly [GO:0000244]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000244; GO:0004843; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0006511; GO:0016579; GO:0031397; GO:0031647; GO:0031685; GO:0034394; GO:0042802; GO:0046872 36125 XM_029354232.2 8 11 1 26 48 NA NA NA NA NA NA 36126 XM_044316250.1 300 1208 135 119 306 Q95JD5 2.02e-54 Sulfotransferase 1B1 (ST1B1) (cSULT1B1) (EC 2.8.2.1) (Sulfotransferase family cytosolic 1B member 1) Canis lupus familiaris (Dog) (Canis familiaris) 3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; epithelial cell differentiation [GO:0030855]; ethanol catabolic process [GO:0006068]; flavonoid metabolic process [GO:0009812]; sulfation [GO:0051923]; thyroid hormone metabolic process [GO:0042403]; xenobiotic metabolic process [GO:0006805] GO:0004062; GO:0005737; GO:0006068; GO:0006805; GO:0008146; GO:0009812; GO:0030855; GO:0042403; GO:0050427; GO:0051923 36127 XM_029324141.2 15 0 45 18 14 NA NA NA NA NA NA 36128 XM_029328079.2 1 0 4 9 50 Q19546 6.2e-43 ATP-dependent helicase wrn-1 (EC 3.6.4.12) (Werner syndrome protein homolog) Caenorhabditis elegans determination of adult lifespan [GO:0008340]; DNA duplex unwinding [GO:0032508]; DNA metabolic process [GO:0006259]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724]; G-quadruplex DNA unwinding [GO:0044806]; multicellular organism aging [GO:0010259]; response to ionizing radiation [GO:0010212]; telomere maintenance [GO:0000723] GO:0000723; GO:0000724; GO:0003677; GO:0005524; GO:0005634; GO:0005654; GO:0005694; GO:0005737; GO:0006259; GO:0006268; GO:0006281; GO:0006310; GO:0008340; GO:0009378; GO:0010212; GO:0010259; GO:0016887; GO:0032508; GO:0035861; GO:0043138; GO:0044806 36129 XM_044318911.1 112 38 308 559 84 Q6V0I7 1.02e-50 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 36130 XM_044318911.1 112 38 308 559 84 Q6V0I7 4.15e-40 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 36131 XM_044318911.1 112 38 308 559 84 Q6V0I7 4.37e-37 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 36132 XM_044318911.1 112 38 308 559 84 Q6V0I7 1.45e-36 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 36133 XM_044318911.1 112 38 308 559 84 Q6V0I7 5.1e-36 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 36134 XM_044318911.1 112 38 308 559 84 Q6V0I7 9.1e-33 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 36135 XM_044318911.1 112 38 308 559 84 Q6V0I7 1.36e-32 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 36136 XM_044318911.1 112 38 308 559 84 Q6V0I7 9.02e-32 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 36137 XM_044318911.1 112 38 308 559 84 Q6V0I7 1.05e-31 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 36138 XM_044318911.1 112 38 308 559 84 Q6V0I7 1.57e-30 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 36139 XM_044318911.1 112 38 308 559 84 Q6V0I7 2.48e-29 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 36140 XM_044318911.1 112 38 308 559 84 Q6V0I7 1.99e-25 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 36141 XM_044318911.1 112 38 308 559 84 Q6V0I7 3.14e-24 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 36142 XM_029336352.2 66 43 48 30 48 NA NA NA NA NA NA 36143 XM_044319886.1 13 1 53 4 32 NA NA NA NA NA NA 36144 XM_029324005.2 5079 5499 4196 5702 2617 A5PJJ7 2.2e-100 Short-chain dehydrogenase/reductase family 16C member 6 (EC 1.1.1.-) Bos taurus (Bovine) NA GO:0005811; GO:0016616 36145 XM_044312674.1 59 26 22 16 62 NA NA NA NA NA NA 36146 XM_029325772.2 107 54 25 44 118 NA NA NA NA NA NA 36147 XR_003824539.2 530 183 254 420 210 NA NA NA NA NA NA 36148 XR_006395943.1 43 52 18 38 86 Q8R149 3.39e-25 BUD13 homolog Mus musculus (Mouse) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0005634; GO:0005654; GO:0005684; GO:0070274; GO:0071005 36149 XR_006395943.1 43 52 18 38 86 Q8R149 3.39e-25 BUD13 homolog Mus musculus (Mouse) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0005634; GO:0005654; GO:0005684; GO:0070274; GO:0071005 36150 XM_029354916.2 1430 931 686 1323 1385 Q86TZ1 5.98e-109 Tetratricopeptide repeat protein 6 (TPR repeat protein 6) Homo sapiens (Human) NA NA 36151 XM_029334676.2 165 135 228 124 174 Q9SSA4 1.26e-31 NA NA NA NA 36152 XR_006393169.1 32 5 23 5 122 NA NA NA NA NA NA 36153 XM_029326858.2 609 433 273 721 726 O15460 9.1e-138 Prolyl 4-hydroxylase subunit alpha-2 (4-PH alpha-2) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-2) Homo sapiens (Human) peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401] GO:0004656; GO:0005506; GO:0005654; GO:0005783; GO:0005788; GO:0005829; GO:0009055; GO:0018401; GO:0031418; GO:0043231 36154 XR_006393532.1 7 2 7 1 13 NA NA NA NA NA NA 36155 XR_006397682.1 68 3 10 5 76 NA NA NA NA NA NA 36156 XM_044317420.1 558 267 318 822 529 P98198 0 Phospholipid-transporting ATPase ID (EC 7.6.2.1) (ATPase class I type 8B member 2) (P4-ATPase flippase complex alpha subunit ATP8B2) Homo sapiens (Human) Golgi organization [GO:0007030]; ion transmembrane transport [GO:0034220]; phospholipid translocation [GO:0045332] GO:0000287; GO:0005524; GO:0005730; GO:0005789; GO:0005794; GO:0005802; GO:0005829; GO:0005886; GO:0007030; GO:0016887; GO:0034220; GO:0045332; GO:0090554; GO:0140326; GO:0140345; GO:1990531 36157 XM_029348853.2 0 0 0 0 27 O75081 4.48e-131 Protein CBFA2T3 (MTG8-related protein 2) (Myeloid translocation gene on chromosome 16 protein) (hMTG16) (Zinc finger MYND domain-containing protein 4) Homo sapiens (Human) granulocyte differentiation [GO:0030851]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of glycolytic process [GO:0045820]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; regulation of aerobic respiration [GO:1903715]; response to hypoxia [GO:0001666] GO:0000139; GO:0001666; GO:0003714; GO:0005634; GO:0005654; GO:0005730; GO:0008285; GO:0030851; GO:0032436; GO:0045820; GO:0045892; GO:0046872; GO:1903715 36158 XM_029345784.2 24 7 105 84 0 B8VIW9 2.8e-112 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 36159 XR_006392802.1 87 0 0 8 36 NA NA NA NA NA NA 36160 XR_006394536.1 425 0 409 0 0 NA NA NA NA NA NA 36161 XM_029337486.2 72 0 0 74 0 NA NA NA NA NA NA 36162 XM_029340859.2 6739 5367 3190 3132 2250 NA NA NA NA NA NA 36163 XM_044314280.1 15 13 3 165 3 NA NA NA NA NA NA 36164 XM_044314161.1 0 6 0 0 9 NA NA NA NA NA NA 36165 XM_029341784.2 3 0 13 0 0 NA NA NA NA NA NA 36166 XM_044328063.1 70 48 40 116 73 Q90678 1.39e-79 Platelet-activating factor acetylhydrolase (PAF acetylhydrolase) (EC 3.1.1.47) (1-alkyl-2-acetylglycerophosphocholine esterase) (2-acetyl-1-alkylglycerophosphocholine esterase) (LDL-associated phospholipase A2) (LDL-PLA(2)) (PAF 2-acylhydrolase) Gallus gallus (Chicken) lipid catabolic process [GO:0016042] GO:0003847; GO:0005615; GO:0016042 36167 XM_029335523.2 202 194 103 154 159 NA NA NA NA NA NA 36168 XR_003826431.1 169 97 142 216 136 NA NA NA NA NA NA 36169 XM_029348968.2 17 0 0 0 79 F1R8P4 3e-94 Glycine receptor subunit alpha-2 Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0004888; GO:0005254; GO:0016594; GO:0016933; GO:0022824; GO:0034707; GO:0042995; GO:0045211; GO:0046872 36170 XM_029348463.2 651 514 470 991 1300 B2RR83 0 3'-5' RNA helicase YTHDC2 (EC 3.6.4.13) (Keen to exit meiosis leaving testes under-populated protein) (Ketu) (YTH domain-containing protein C2) (mYTHDC2) Mus musculus (Mouse) germline cell cycle switching, mitotic to meiotic cell cycle [GO:0051729]; meiotic cell cycle [GO:0051321]; oocyte development [GO:0048599]; positive regulation by host of viral genome replication [GO:0044829]; response to interleukin-1 [GO:0070555]; response to tumor necrosis factor [GO:0034612]; spermatid development [GO:0007286] GO:0003723; GO:0005524; GO:0005634; GO:0005737; GO:0005783; GO:0007286; GO:0008186; GO:0016887; GO:0034458; GO:0034612; GO:0035770; GO:0044829; GO:0048471; GO:0048599; GO:0051321; GO:0051729; GO:0070063; GO:0070555; GO:1990247 36171 XM_029348463.2 651 514 470 991 1300 B2RR83 1.59e-123 3'-5' RNA helicase YTHDC2 (EC 3.6.4.13) (Keen to exit meiosis leaving testes under-populated protein) (Ketu) (YTH domain-containing protein C2) (mYTHDC2) Mus musculus (Mouse) germline cell cycle switching, mitotic to meiotic cell cycle [GO:0051729]; meiotic cell cycle [GO:0051321]; oocyte development [GO:0048599]; positive regulation by host of viral genome replication [GO:0044829]; response to interleukin-1 [GO:0070555]; response to tumor necrosis factor [GO:0034612]; spermatid development [GO:0007286] GO:0003723; GO:0005524; GO:0005634; GO:0005737; GO:0005783; GO:0007286; GO:0008186; GO:0016887; GO:0034458; GO:0034612; GO:0035770; GO:0044829; GO:0048471; GO:0048599; GO:0051321; GO:0051729; GO:0070063; GO:0070555; GO:1990247 36172 XM_029348463.2 651 514 470 991 1300 B2RR83 1.5e-51 3'-5' RNA helicase YTHDC2 (EC 3.6.4.13) (Keen to exit meiosis leaving testes under-populated protein) (Ketu) (YTH domain-containing protein C2) (mYTHDC2) Mus musculus (Mouse) germline cell cycle switching, mitotic to meiotic cell cycle [GO:0051729]; meiotic cell cycle [GO:0051321]; oocyte development [GO:0048599]; positive regulation by host of viral genome replication [GO:0044829]; response to interleukin-1 [GO:0070555]; response to tumor necrosis factor [GO:0034612]; spermatid development [GO:0007286] GO:0003723; GO:0005524; GO:0005634; GO:0005737; GO:0005783; GO:0007286; GO:0008186; GO:0016887; GO:0034458; GO:0034612; GO:0035770; GO:0044829; GO:0048471; GO:0048599; GO:0051321; GO:0051729; GO:0070063; GO:0070555; GO:1990247 36173 XR_006396975.1 1171 2343 1480 1397 1017 NA NA NA NA NA NA 36174 XM_029351983.2 144 0 0 0 0 Q5F364 0 Multidrug resistance-associated protein 1 (EC 7.6.2.2) (ATP-binding cassette sub-family C member 1) (Glutathione-S-conjugate-translocating ATPase ABCC1) (EC 7.6.2.3) (Leukotriene C(4) transporter) (LTC4 transporter) Gallus gallus (Chicken) glutathione transmembrane transport [GO:0034775]; lipid transport [GO:0006869]; transmembrane transport [GO:0055085]; xenobiotic transport [GO:0042908] GO:0005524; GO:0006869; GO:0008559; GO:0016020; GO:0016323; GO:0016887; GO:0034634; GO:0034775; GO:0042626; GO:0042908; GO:0055085 36175 XM_044316558.1 506 233 192 386 542 Q6ZQB6 1.32e-83 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 (EC 2.7.4.24) (Diphosphoinositol pentakisphosphate kinase 2) (Histidine acid phosphatase domain-containing protein 1) (InsP6 and PP-IP5 kinase 2) (VIP1 homolog 2) (mmVIP2) Mus musculus (Mouse) inositol metabolic process [GO:0006020]; inositol phosphate biosynthetic process [GO:0032958]; phosphorylation [GO:0016310]; sensory perception of sound [GO:0007605] GO:0000827; GO:0000828; GO:0000829; GO:0000832; GO:0005524; GO:0005829; GO:0006020; GO:0007605; GO:0016310; GO:0032958; GO:0033857; GO:0052723; GO:0052724 36176 XM_044311686.1 91 28 56 97 226 B8VIU6 2.73e-59 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 36177 XM_029332695.2 1982 10 373 5672 960 NA NA NA NA NA NA 36178 XR_006393243.1 0 0 0 0 7 NA NA NA NA NA NA 36179 XM_044311748.1 0 0 0 1 9 NA NA NA NA NA NA 36180 XM_044315638.1 0 10 0 0 66 NA NA NA NA NA NA 36181 XM_029356738.2 58 46 67 90 153 NA NA NA NA NA NA 36182 XR_006391739.1 0 0 0 0 56 NA NA NA NA NA NA 36183 XM_029324278.2 273 179 102 222 244 Q6NUT3 1.16e-60 Major facilitator superfamily domain-containing protein 12 Homo sapiens (Human) carbohydrate transport [GO:0008643]; cysteine transmembrane transport [GO:1903712]; melanin biosynthetic process [GO:0042438]; negative regulation of melanin biosynthetic process [GO:0048022]; organic substance transport [GO:0071702]; pigment metabolic process involved in pigmentation [GO:0043474]; regulation of melanin biosynthetic process [GO:0048021] GO:0005764; GO:0005765; GO:0005770; GO:0005886; GO:0008643; GO:0015293; GO:0033162; GO:0033229; GO:0042438; GO:0042470; GO:0043474; GO:0048021; GO:0048022; GO:0071702; GO:1903712 36184 XM_029324278.2 273 179 102 222 244 Q6NUT3 3.49e-36 Major facilitator superfamily domain-containing protein 12 Homo sapiens (Human) carbohydrate transport [GO:0008643]; cysteine transmembrane transport [GO:1903712]; melanin biosynthetic process [GO:0042438]; negative regulation of melanin biosynthetic process [GO:0048022]; organic substance transport [GO:0071702]; pigment metabolic process involved in pigmentation [GO:0043474]; regulation of melanin biosynthetic process [GO:0048021] GO:0005764; GO:0005765; GO:0005770; GO:0005886; GO:0008643; GO:0015293; GO:0033162; GO:0033229; GO:0042438; GO:0042470; GO:0043474; GO:0048021; GO:0048022; GO:0071702; GO:1903712 36185 XM_044319754.1 449 310 167 329 219 NA NA NA NA NA NA 36186 XM_044311365.1 31 43 8 4 43 NA NA NA NA NA NA 36187 XM_029327778.2 12507 8119 5222 8770 7132 Q16829 5.9e-87 Dual specificity protein phosphatase 7 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity protein phosphatase PYST2) Homo sapiens (Human) ERK1 and ERK2 cascade [GO:0070371]; MAPK cascade [GO:0000165]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; peptidyl-tyrosine dephosphorylation [GO:0035335] GO:0000165; GO:0004721; GO:0004725; GO:0005654; GO:0005737; GO:0005829; GO:0008138; GO:0008330; GO:0017017; GO:0017018; GO:0035335; GO:0043407; GO:0043409; GO:0070371 36188 XM_029344941.2 5972 4149 3070 4999 4443 Q14247 1.66e-138 Src substrate cortactin (Amplaxin) (Oncogene EMS1) Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; cell motility [GO:0048870]; dendritic spine maintenance [GO:0097062]; extrinsic apoptotic signaling pathway [GO:0097191]; focal adhesion assembly [GO:0048041]; intracellular protein transport [GO:0006886]; lamellipodium organization [GO:0097581]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; neuron projection morphogenesis [GO:0048812]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of smooth muscle contraction [GO:0045987]; receptor-mediated endocytosis [GO:0006898]; regulation of actin filament polymerization [GO:0030833]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of axon extension [GO:0030516]; substrate-dependent cell migration, cell extension [GO:0006930] GO:0001726; GO:0002102; GO:0005522; GO:0005737; GO:0005783; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0005905; GO:0005925; GO:0005938; GO:0006886; GO:0006898; GO:0006930; GO:0008076; GO:0030027; GO:0030427; GO:0030516; GO:0030833; GO:0030838; GO:0030863; GO:0030864; GO:0031532; GO:0043197; GO:0043231; GO:0045296; GO:0045987; GO:0048041; GO:0048812; GO:0048870; GO:0051015; GO:0097062; GO:0097191; GO:0097581; GO:1903146; GO:1990023; GO:2001237 36189 XM_029349103.2 785 1378 557 1466 1008 Q8K215 4.03e-26 LYR motif-containing protein 4 Mus musculus (Mouse) [2Fe-2S] cluster assembly [GO:0044571]; [4Fe-4S] cluster assembly [GO:0044572]; iron-sulfur cluster assembly [GO:0016226] GO:0005739; GO:0016226; GO:0016604; GO:0042803; GO:0044571; GO:0044572; GO:0099128; GO:1990221; GO:1990229 36190 XM_044319620.1 36 23 39 7 9 NA NA NA NA NA NA 36191 XM_044323887.1 228 0 3 702 0 NA NA NA NA NA NA 36192 XM_044328070.1 422 313 381 751 0 NA NA NA NA NA NA 36193 XM_044317882.1 141 95 18 53 32 P54131 1.28e-66 Neuronal acetylcholine receptor subunit alpha-7 Bos taurus (Bovine) calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; cognition [GO:0050890]; ion transmembrane transport [GO:0034220]; negative regulation of tumor necrosis factor production [GO:0032720]; nervous system process [GO:0050877]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAPK cascade [GO:0043410]; regulation of membrane potential [GO:0042391]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271] GO:0001540; GO:0001666; GO:0005231; GO:0005886; GO:0005892; GO:0006816; GO:0006874; GO:0007165; GO:0007268; GO:0007271; GO:0008284; GO:0015464; GO:0015643; GO:0017081; GO:0022848; GO:0030594; GO:0032720; GO:0034220; GO:0035094; GO:0042166; GO:0042391; GO:0042803; GO:0043005; GO:0043410; GO:0045202; GO:0045211; GO:0045766; GO:0050877; GO:0050890; GO:1904315 36194 XM_044321397.1 0 5 13 4 0 NA NA NA NA NA NA 36195 XM_029336765.2 6988 6785 4234 6997 9811 Q9WU63 4.92e-35 Heme-binding protein 2 (Protein SOUL) Mus musculus (Mouse) negative regulation of mitochondrial membrane potential [GO:0010917]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of necrotic cell death [GO:0010940] GO:0005737; GO:0005739; GO:0010917; GO:0010940; GO:0020037; GO:0035794 36196 XM_044313285.1 8 3 4 5 4 NA NA NA NA NA NA 36197 XM_044307192.1 3 0 0 9 5 NA NA NA NA NA NA 36198 XM_044316602.1 101 131 27 77 40 NA NA NA NA NA NA 36199 XM_029323630.2 1747 970 953 1932 1570 B0CM26 0 Cilia- and flagella-associated protein 69 Papio anubis (Olive baboon) cell differentiation [GO:0030154]; olfactory behavior [GO:0042048]; positive regulation of fertilization [GO:1905516]; positive regulation of flagellated sperm motility [GO:1902093]; response to odorant [GO:1990834]; sensory perception of smell [GO:0007608]; spermatogenesis [GO:0007283] GO:0005737; GO:0007283; GO:0007608; GO:0030154; GO:0042048; GO:0097225; GO:0097730; GO:1902093; GO:1905516; GO:1990834 36200 XM_044311707.1 437 287 366 566 576 A1L0Y2 0 Neuralized-like protein 4 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737; GO:0005814 36201 XM_044311707.1 437 287 366 566 576 A1L0Y2 1.25e-145 Neuralized-like protein 4 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737; GO:0005814 36202 XM_044311707.1 437 287 366 566 576 A1L0Y2 5.36e-144 Neuralized-like protein 4 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737; GO:0005814 36203 XM_044311707.1 437 287 366 566 576 A1L0Y2 5.47e-127 Neuralized-like protein 4 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737; GO:0005814 36204 XM_044311707.1 437 287 366 566 576 A1L0Y2 2.24e-30 Neuralized-like protein 4 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737; GO:0005814 36205 XM_044311707.1 437 287 366 566 576 A1L0Y2 6.06e-24 Neuralized-like protein 4 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737; GO:0005814 36206 XM_029357968.2 446 297 222 428 284 Q8N697 5.48e-62 Solute carrier family 15 member 4 (Peptide transporter 4) (Peptide/histidine transporter 1) (hPHT1) Homo sapiens (Human) dipeptide import across plasma membrane [GO:0140206]; histidine transport [GO:0015817]; innate immune response [GO:0045087]; ion transport [GO:0006811]; L-histidine transmembrane export from vacuole [GO:0089708]; mast cell homeostasis [GO:0033023]; peptidoglycan transport [GO:0015835]; positive regulation of innate immune response [GO:0045089]; positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [GO:0070430]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of toll-like receptor 7 signaling pathway [GO:0034157]; positive regulation of toll-like receptor 8 signaling pathway [GO:0034161]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; protein transport [GO:0015031]; regulation of isotype switching to IgG isotypes [GO:0048302]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424]; transmembrane transport [GO:0055085] GO:0005290; GO:0005765; GO:0005886; GO:0006811; GO:0015031; GO:0015333; GO:0015647; GO:0015817; GO:0015835; GO:0016020; GO:0022857; GO:0031901; GO:0033023; GO:0034157; GO:0034161; GO:0034165; GO:0035579; GO:0036020; GO:0045087; GO:0045089; GO:0048302; GO:0055085; GO:0070424; GO:0070430; GO:0070434; GO:0071916; GO:0089708; GO:0140206 36207 XR_006392289.1 39 3 16 14 17 NA NA NA NA NA NA 36208 XM_044312633.1 38 2 23 1 31 NA NA NA NA NA NA 36209 XM_029351016.2 182 56 87 66 167 P09011 1.45e-35 Lens fiber major intrinsic protein (Aquaporin-0) (MIP26) (MP26) Rattus norvegicus (Rat) canalicular bile acid transport [GO:0015722]; gap junction-mediated intercellular transport [GO:1990349]; lens development in camera-type eye [GO:0002088]; positive regulation of cell adhesion [GO:0045785]; protein homotetramerization [GO:0051289]; transmembrane transport [GO:0055085]; visual perception [GO:0007601]; water transport [GO:0006833] GO:0002088; GO:0005212; GO:0005516; GO:0005783; GO:0005886; GO:0005921; GO:0006833; GO:0007601; GO:0015250; GO:0015722; GO:0016020; GO:0016324; GO:0043231; GO:0045785; GO:0046691; GO:0051289; GO:0055085; GO:1990349 36210 XM_044313390.1 22 13 11 7 27 NA NA NA NA NA NA 36211 XM_029357414.2 56 35 42 74 77 Q6DF94 4.85e-27 Spindle and centriole-associated protein 1 (Coiled-coil domain-containing protein 52) Xenopus laevis (African clawed frog) cell division [GO:0051301]; mitotic spindle assembly [GO:0090307]; regulation of centriole replication [GO:0046599] GO:0005737; GO:0005814; GO:0005819; GO:0046599; GO:0051301; GO:0090307 36212 XM_029344234.2 553 497 271 476 250 E1BNS6 4.97e-27 Sperm-associated antigen 8 Bos taurus (Bovine) cell cycle [GO:0007049]; cell differentiation [GO:0030154]; positive regulation of protein binding [GO:0032092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; single fertilization [GO:0007338]; spermatogenesis [GO:0007283] GO:0001669; GO:0001673; GO:0005634; GO:0005737; GO:0005819; GO:0005879; GO:0007049; GO:0007283; GO:0007338; GO:0008017; GO:0030154; GO:0032092; GO:0045944 36213 XM_029355494.2 0 42 0 55 20 Q5ZIP4 0 5'-3' exoribonuclease 2 (EC 3.1.13.-) Gallus gallus (Chicken) DNA catabolic process, exonucleolytic [GO:0000738]; mRNA processing [GO:0006397]; nuclear-transcribed mRNA catabolic process [GO:0000956]; spermatogenesis [GO:0007283] GO:0000738; GO:0000956; GO:0001147; GO:0003723; GO:0004534; GO:0005634; GO:0005654; GO:0005730; GO:0006397; GO:0007283; GO:0008409; GO:0016235; GO:0042802; GO:0046872 36214 XM_029356722.2 950 483 454 660 913 Q2KHP8 0 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1 (EC 4.1.3.44) (Radical S-adenosyl methionine and flavodoxin domain-containing protein 1) (tRNA wybutosine-synthesizing protein 1 homolog) (tRNA-yW-synthesizing protein) Xenopus laevis (African clawed frog) tRNA processing [GO:0008033] GO:0008033; GO:0010181; GO:0046872; GO:0051539; GO:0102521 36215 XM_029340393.2 986 385 40 479 234 E9QAT4 1.12e-45 Protein transport protein Sec16A (SEC16 homolog A) (p250) Mus musculus (Mouse) autophagy [GO:0006914]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; Golgi to plasma membrane transport [GO:0006893]; protein exit from endoplasmic reticulum [GO:0032527]; protein localization to endoplasmic reticulum exit site [GO:0070973]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; response to endoplasmic reticulum stress [GO:0034976] GO:0000139; GO:0005789; GO:0005829; GO:0006888; GO:0006893; GO:0006914; GO:0007029; GO:0007030; GO:0012507; GO:0031090; GO:0032527; GO:0034976; GO:0048208; GO:0048471; GO:0050821; GO:0070971; GO:0070973; GO:0072659 36216 XM_029343856.2 7 0 1 13 7 NA NA NA NA NA NA 36217 XM_029333687.2 1060 2470 1019 1485 896 O96952 1.28e-24 Thioredoxin (Trx) Geodia cydonium (Sponge) NA GO:0005737; GO:0015035 36218 XM_044320028.1 227 109 89 98 71 Q9NU02 0 Ankyrin repeat and EF-hand domain-containing protein 1 (Ankyrin repeat domain-containing protein 5) Homo sapiens (Human) NA GO:0005509 36219 XM_029346700.2 4076 6561 3170 4368 2564 Q2TBP7 2.62e-31 c-Myc-binding protein (Associate of Myc 1) (AMY-1) Bos taurus (Bovine) regulation of DNA-templated transcription [GO:0006355] GO:0003713; GO:0005634; GO:0005737; GO:0006355 36220 XM_029325791.2 23 49 11 89 80 Q5RJA1 8.17e-148 DNA-binding protein RFX6 (Regulatory factor X 6) Danio rerio (Zebrafish) (Brachydanio rerio) endocrine pancreas development [GO:0031018]; glucose homeostasis [GO:0042593]; pancreatic A cell differentiation [GO:0003310]; pancreatic D cell differentiation [GO:0003311]; pancreatic epsilon cell differentiation [GO:0090104]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of insulin secretion [GO:0050796]; regulation of transcription by RNA polymerase II [GO:0006357]; type B pancreatic cell differentiation [GO:0003309] GO:0000976; GO:0000978; GO:0000981; GO:0003309; GO:0003310; GO:0003311; GO:0005634; GO:0006357; GO:0031018; GO:0035774; GO:0042593; GO:0045893; GO:0045944; GO:0050796; GO:0090104 36221 XM_044319286.1 0 41 25 60 120 Q08BM0 4.93e-54 tRNA methyltransferase 10 homolog B (EC 2.1.1.221) (RNA (guanine-9-)-methyltransferase domain-containing protein 3) (tRNA (guanine(9)-N(1))-methyltransferase TRMT10B) Danio rerio (Zebrafish) (Brachydanio rerio) tRNA N1-guanine methylation [GO:0002939] GO:0000049; GO:0002939; GO:0005634; GO:0005654; GO:0009019; GO:0052905 36222 XM_029350174.2 120 56 43 138 85 NA NA NA NA NA NA 36223 XM_044308860.1 273 113 0 63 258 Q8WVM7 0 Cohesin subunit SA-1 (SCC3 homolog 1) (Stromal antigen 1) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic sister chromatid cohesion [GO:0034087]; localization [GO:0051179]; mitotic spindle assembly [GO:0090307]; sister chromatid cohesion [GO:0007062] GO:0000775; GO:0000785; GO:0003682; GO:0005634; GO:0005654; GO:0005694; GO:0005829; GO:0007062; GO:0008278; GO:0016363; GO:0016604; GO:0034087; GO:0051179; GO:0051301; GO:0090307; GO:0097431 36224 XM_044317286.1 311 331 243 534 592 Q9Y394 1.07e-72 Dehydrogenase/reductase SDR family member 7 (EC 1.1.1.-) (Retinal short-chain dehydrogenase/reductase 4) (retSDR4) (Short chain dehydrogenase/reductase family 34C member 1) (Protein SDR34C1) Homo sapiens (Human) NA GO:0004090; GO:0005789; GO:0016020; GO:0016616; GO:0052650 36225 XM_044314309.1 63 14 50 97 212 NA NA NA NA NA NA 36226 XM_029352546.2 303 155 94 457 264 P98133 1.62e-21 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 36227 XM_044307719.1 1818 2411 1083 2141 1357 Q5ZIF1 8.02e-101 Adipocyte plasma membrane-associated protein Gallus gallus (Chicken) biosynthetic process [GO:0009058] GO:0004064; GO:0009058; GO:0009986; GO:0016020; GO:0016844 36228 XR_006394476.1 19 11 6 3 28 NA NA NA NA NA NA 36229 XM_029348039.2 1748 1921 854 1288 1229 Q5U465 3.01e-40 Coiled-coil domain-containing protein 125 Mus musculus (Mouse) activation of GTPase activity [GO:0090630]; negative regulation of cell motility [GO:2000146]; negative regulation of Rho protein signal transduction [GO:0035024] GO:0005737; GO:0035024; GO:0042802; GO:0090630; GO:2000146 36230 XM_044318183.1 134 372 292 200 151 NA NA NA NA NA NA 36231 XM_044319064.1 121 17 23 51 23 O75751 3.45e-63 Solute carrier family 22 member 3 (Extraneuronal monoamine transporter) (EMT) (Organic cation transporter 3) Homo sapiens (Human) dopamine uptake [GO:0090494]; epinephrine uptake [GO:0051625]; histamine metabolic process [GO:0001692]; histamine uptake [GO:0051615]; monoamine transport [GO:0015844]; monocarboxylic acid transport [GO:0015718]; neurotransmitter transport [GO:0006836]; norepinephrine uptake [GO:0051620]; organic anion transport [GO:0015711]; organic cation transport [GO:0015695]; purine-containing compound transmembrane transport [GO:0072530]; quaternary ammonium group transport [GO:0015697]; regulation of appetite [GO:0032098]; serotonin uptake [GO:0051610]; spermidine transport [GO:0015848]; toxin transport [GO:1901998]; transport across blood-brain barrier [GO:0150104]; xenobiotic transport [GO:0042908] GO:0001692; GO:0005326; GO:0005886; GO:0006836; GO:0008504; GO:0008514; GO:0015101; GO:0015606; GO:0015651; GO:0015695; GO:0015697; GO:0015711; GO:0015718; GO:0015844; GO:0015848; GO:0016020; GO:0019534; GO:0032098; GO:0042908; GO:0043025; GO:0051610; GO:0051615; GO:0051620; GO:0051625; GO:0072530; GO:0090494; GO:0098793; GO:0150104; GO:1901998 36232 XR_006396179.1 52 82 33 27 116 NA NA NA NA NA NA 36233 XM_044318374.1 38 0 7 1 54 NA NA NA NA NA NA 36234 XM_029338498.2 20244 25182 11622 19451 17689 P52301 8.66e-121 GTP-binding nuclear protein Ran (EC 3.6.5.-) (GTPase Ran) (Ras-like protein TC4) (Ras-related nuclear protein) Xenopus laevis (African clawed frog) eye development [GO:0001654]; GTP metabolic process [GO:0046039]; mitotic sister chromatid segregation [GO:0000070]; protein import into nucleus [GO:0006606]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015] GO:0000055; GO:0000056; GO:0000070; GO:0000287; GO:0001654; GO:0003924; GO:0005525; GO:0005634; GO:0005635; GO:0005829; GO:0006606; GO:0046039; GO:0061015 36235 XM_029336477.2 1452 422 322 1502 688 NA NA NA NA NA NA 36236 XM_044309501.1 0 0 8 6 12 NA NA NA NA NA NA 36237 XR_006396347.1 0 0 0 0 142 NA NA NA NA NA NA 36238 XM_029331629.2 2043 2347 1061 2298 812 Q8R3J5 3.32e-53 Glutathione-specific gamma-glutamylcyclotransferase 1 (Gamma-GCG 1) (EC 4.3.2.7) (Blocks Notch protein) (Botch) (Cation transport regulator-like protein 1) Mus musculus (Mouse) glutathione catabolic process [GO:0006751]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein processing [GO:0010955]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; response to unfolded protein [GO:0006986] GO:0003839; GO:0005112; GO:0005737; GO:0005802; GO:0005829; GO:0006751; GO:0006986; GO:0007219; GO:0010955; GO:0022008; GO:0045746; GO:0061928; GO:0070059 36239 XM_044322142.1 0 0 189 2 0 A7T1N0 0 Transient receptor potential cation channel subfamily M member-like 2 (nvTRPM2) Nematostella vectensis (Starlet sea anemone) calcium ion transmembrane transport [GO:0070588]; cation transmembrane transport [GO:0098655]; sodium ion transmembrane transport [GO:0035725] GO:0005261; GO:0005886; GO:0015280; GO:0035725; GO:0046872; GO:0047631; GO:0070588; GO:0098655; GO:0099604 36240 XM_044324859.1 7 37 5 8 35 NA NA NA NA NA NA 36241 XM_044318181.1 168 52 46 259 302 NA NA NA NA NA NA 36242 XM_029337380.2 211 0 58 26 73 O95294 0 RasGAP-activating-like protein 1 (RAS protein activator like 1) (Ras GTPase-activating-like protein) Homo sapiens (Human) cell differentiation [GO:0030154]; cellular response to calcium ion [GO:0071277]; intracellular signal transduction [GO:0035556]; negative regulation of Ras protein signal transduction [GO:0046580]; positive regulation of dendrite extension [GO:1903861]; regulation of GTPase activity [GO:0043087]; signal transduction [GO:0007165] GO:0005096; GO:0005543; GO:0005829; GO:0007165; GO:0030154; GO:0035556; GO:0043087; GO:0046580; GO:0046872; GO:0071277; GO:1903861 36243 XM_044319085.1 0 34 0 0 0 NA NA NA NA NA NA 36244 XM_029350696.2 424 340 273 634 670 NA NA NA NA NA NA 36245 XM_044328308.1 212 53 53 70 280 NA NA NA NA NA NA 36246 XM_044315219.1 411 403 328 507 512 Q13615 0 Myotubularin-related protein 3 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 1) (FYVE-DSP1) (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64) (Zinc finger FYVE domain-containing protein 10) Homo sapiens (Human) cellular response to glucose starvation [GO:0042149]; macroautophagy [GO:0016236]; phosphatidylinositol 5-phosphate metabolic process [GO:1904562]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; protein dephosphorylation [GO:0006470]; regulation of autophagosome assembly [GO:2000785]; regulation of autophagy [GO:0010506]; regulation of phosphatidylinositol dephosphorylation [GO:0060304] GO:0004438; GO:0004722; GO:0004725; GO:0005737; GO:0005829; GO:0006470; GO:0006661; GO:0008138; GO:0010506; GO:0016020; GO:0016236; GO:0019898; GO:0019903; GO:0042149; GO:0046856; GO:0046872; GO:0052629; GO:0060304; GO:1904562; GO:2000785 36247 XM_044315219.1 411 403 328 507 512 Q13615 4.07e-35 Myotubularin-related protein 3 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 1) (FYVE-DSP1) (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64) (Zinc finger FYVE domain-containing protein 10) Homo sapiens (Human) cellular response to glucose starvation [GO:0042149]; macroautophagy [GO:0016236]; phosphatidylinositol 5-phosphate metabolic process [GO:1904562]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; protein dephosphorylation [GO:0006470]; regulation of autophagosome assembly [GO:2000785]; regulation of autophagy [GO:0010506]; regulation of phosphatidylinositol dephosphorylation [GO:0060304] GO:0004438; GO:0004722; GO:0004725; GO:0005737; GO:0005829; GO:0006470; GO:0006661; GO:0008138; GO:0010506; GO:0016020; GO:0016236; GO:0019898; GO:0019903; GO:0042149; GO:0046856; GO:0046872; GO:0052629; GO:0060304; GO:1904562; GO:2000785 36248 XM_044320256.1 17 0 8 0 0 NA NA NA NA NA NA 36249 XM_029356999.2 1071 710 517 990 916 Q6PFX9 0 Poly [ADP-ribose] polymerase tankyrase-1 (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 5) (ARTD5) (Protein poly-ADP-ribosyltransferase tankyrase-1) (EC 2.4.2.-) (TRF1-interacting ankyrin-related ADP-ribose polymerase 1) (Tankyrase I) (Tankyrase-1) (TANK1) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to nutrient [GO:0031670]; mRNA transport [GO:0051028]; negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric [GO:1904908]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of telomeric DNA binding [GO:1904743]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; protein transport [GO:0015031]; Wnt signaling pathway [GO:0016055] GO:0000139; GO:0000209; GO:0000781; GO:0003950; GO:0005634; GO:0005643; GO:0005654; GO:0005737; GO:0005794; GO:0005815; GO:0005829; GO:0007049; GO:0008270; GO:0015031; GO:0016055; GO:0016604; GO:0016779; GO:0018105; GO:0018107; GO:0031670; GO:0031965; GO:0032212; GO:0042393; GO:0045944; GO:0051028; GO:0051301; GO:0051973; GO:0070198; GO:0070212; GO:0070213; GO:0090263; GO:0097431; GO:1904355; GO:1904357; GO:1904743; GO:1904908; GO:1990404 36250 XM_029342814.2 10 7 0 30 268 NA NA NA NA NA NA 36251 XM_029329382.2 554 504 496 910 1170 Q8BI21 2.51e-29 E3 ubiquitin-protein ligase RNF38 (EC 2.3.2.27) (RING finger protein 38) (RING-type E3 ubiquitin transferase RNF38) Mus musculus (Mouse) protein ubiquitination [GO:0016567] GO:0005634; GO:0005654; GO:0016567; GO:0036126; GO:0046872; GO:0061630 36252 XM_029338621.2 0 0 27 55 50 P21521 5.64e-123 Synaptotagmin 1 (p65) Drosophila melanogaster (Fruit fly) calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; chemical synaptic transmission [GO:0007268]; clathrin-dependent synaptic vesicle endocytosis [GO:0150007]; larval locomotory behavior [GO:0008345]; neurotransmitter secretion [GO:0007269]; positive regulation of vesicle fusion [GO:0031340]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of neuromuscular synaptic transmission [GO:1900073]; regulation of pole plasm oskar mRNA localization [GO:0007317]; regulation of synapse structure or activity [GO:0050803]; rhythmic synaptic transmission [GO:0060024]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle exocytosis [GO:0016079]; vesicle-mediated transport [GO:0016192] GO:0000149; GO:0001786; GO:0005509; GO:0005544; GO:0005886; GO:0007268; GO:0007269; GO:0007317; GO:0008021; GO:0008345; GO:0014059; GO:0016020; GO:0016079; GO:0016192; GO:0017156; GO:0017158; GO:0019905; GO:0030276; GO:0030424; GO:0030672; GO:0031045; GO:0031340; GO:0031594; GO:0042803; GO:0043195; GO:0048488; GO:0048791; GO:0050803; GO:0060024; GO:0070382; GO:0071277; GO:0150007; GO:1900073 36253 XM_029349940.2 0 0 0 34 0 NA NA NA NA NA NA 36254 XM_044324668.1 22 97 0 0 0 Q01484 1.09e-22 Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin) Homo sapiens (Human) atrial cardiac muscle cell action potential [GO:0086014]; atrial cardiac muscle cell to AV node cell communication [GO:0086066]; atrial septum development [GO:0003283]; cellular calcium ion homeostasis [GO:0006874]; endocytosis [GO:0006897]; membrane depolarization during SA node cell action potential [GO:0086046]; paranodal junction assembly [GO:0030913]; positive regulation of calcium ion transmembrane transporter activity [GO:1901021]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cation channel activity [GO:2001259]; positive regulation of gene expression [GO:0010628]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to endoplasmic reticulum [GO:0070972]; protein localization to M-band [GO:0036309]; protein localization to organelle [GO:0033365]; protein localization to plasma membrane [GO:0072659]; protein localization to T-tubule [GO:0036371]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; regulation of atrial cardiac muscle cell action potential [GO:0098910]; regulation of calcium ion transmembrane transporter activity [GO:1901019]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of heart rate [GO:0002027]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of protein stability [GO:0031647]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of SA node cell action potential [GO:0098907]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; response to methylmercury [GO:0051597]; SA node cell action potential [GO:0086015]; SA node cell to atrial cardiac muscle cell communication [GO:0086070]; sarcoplasmic reticulum calcium ion transport [GO:0070296]; T-tubule organization [GO:0033292]; ventricular cardiac muscle cell action potential [GO:0086005] GO:0002027; GO:0003283; GO:0005200; GO:0005739; GO:0005764; GO:0005769; GO:0005829; GO:0005856; GO:0005886; GO:0006874; GO:0006897; GO:0008093; GO:0008104; GO:0010628; GO:0010881; GO:0010882; GO:0014704; GO:0015031; GO:0016323; GO:0016324; GO:0019899; GO:0019901; GO:0030018; GO:0030315; GO:0030507; GO:0030674; GO:0030913; GO:0031430; GO:0031647; GO:0031672; GO:0033292; GO:0033365; GO:0034394; GO:0036309; GO:0036371; GO:0042383; GO:0043005; GO:0043034; GO:0043268; GO:0044325; GO:0045121; GO:0045211; GO:0050821; GO:0051117; GO:0051279; GO:0051597; GO:0051924; GO:0051928; GO:0055037; GO:0055117; GO:0060307; GO:0070296; GO:0070972; GO:0072659; GO:0086004; GO:0086005; GO:0086014; GO:0086015; GO:0086046; GO:0086066; GO:0086070; GO:0086091; GO:0098907; GO:0098910; GO:0140031; GO:1901018; GO:1901019; GO:1901021; GO:2001259 36255 XM_044324668.1 22 97 0 0 0 Q01484 9.96e-21 Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin) Homo sapiens (Human) atrial cardiac muscle cell action potential [GO:0086014]; atrial cardiac muscle cell to AV node cell communication [GO:0086066]; atrial septum development [GO:0003283]; cellular calcium ion homeostasis [GO:0006874]; endocytosis [GO:0006897]; membrane depolarization during SA node cell action potential [GO:0086046]; paranodal junction assembly [GO:0030913]; positive regulation of calcium ion transmembrane transporter activity [GO:1901021]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cation channel activity [GO:2001259]; positive regulation of gene expression [GO:0010628]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to endoplasmic reticulum [GO:0070972]; protein localization to M-band [GO:0036309]; protein localization to organelle [GO:0033365]; protein localization to plasma membrane [GO:0072659]; protein localization to T-tubule [GO:0036371]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; regulation of atrial cardiac muscle cell action potential [GO:0098910]; regulation of calcium ion transmembrane transporter activity [GO:1901019]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of heart rate [GO:0002027]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of protein stability [GO:0031647]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of SA node cell action potential [GO:0098907]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; response to methylmercury [GO:0051597]; SA node cell action potential [GO:0086015]; SA node cell to atrial cardiac muscle cell communication [GO:0086070]; sarcoplasmic reticulum calcium ion transport [GO:0070296]; T-tubule organization [GO:0033292]; ventricular cardiac muscle cell action potential [GO:0086005] GO:0002027; GO:0003283; GO:0005200; GO:0005739; GO:0005764; GO:0005769; GO:0005829; GO:0005856; GO:0005886; GO:0006874; GO:0006897; GO:0008093; GO:0008104; GO:0010628; GO:0010881; GO:0010882; GO:0014704; GO:0015031; GO:0016323; GO:0016324; GO:0019899; GO:0019901; GO:0030018; GO:0030315; GO:0030507; GO:0030674; GO:0030913; GO:0031430; GO:0031647; GO:0031672; GO:0033292; GO:0033365; GO:0034394; GO:0036309; GO:0036371; GO:0042383; GO:0043005; GO:0043034; GO:0043268; GO:0044325; GO:0045121; GO:0045211; GO:0050821; GO:0051117; GO:0051279; GO:0051597; GO:0051924; GO:0051928; GO:0055037; GO:0055117; GO:0060307; GO:0070296; GO:0070972; GO:0072659; GO:0086004; GO:0086005; GO:0086014; GO:0086015; GO:0086046; GO:0086066; GO:0086070; GO:0086091; GO:0098907; GO:0098910; GO:0140031; GO:1901018; GO:1901019; GO:1901021; GO:2001259 36256 XM_029352876.2 0 9 0 9 10 NA NA NA NA NA NA 36257 XM_044318921.1 254 15 134 107 13 NA NA NA NA NA NA 36258 XM_044317347.1 448 19 114 422 431 P0C5E4 1.77e-26 Phosphatidylinositol phosphatase PTPRQ (EC 3.1.3.-) (Receptor-type tyrosine-protein phosphatase Q) (PTP-RQ) (R-PTP-Q) (EC 3.1.3.48) Mus musculus (Mouse) detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; hematopoietic progenitor cell differentiation [GO:0002244]; inner ear morphogenesis [GO:0042472]; neuromuscular process controlling balance [GO:0050885]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; regulation of fat cell differentiation [GO:0045598]; vestibular receptor cell morphogenesis [GO:0060116] GO:0002244; GO:0004725; GO:0016020; GO:0032421; GO:0042472; GO:0043235; GO:0045598; GO:0050885; GO:0050910; GO:0060116; GO:1990264 36259 XM_044317347.1 448 19 114 422 431 P0C5E4 6.05e-26 Phosphatidylinositol phosphatase PTPRQ (EC 3.1.3.-) (Receptor-type tyrosine-protein phosphatase Q) (PTP-RQ) (R-PTP-Q) (EC 3.1.3.48) Mus musculus (Mouse) detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; hematopoietic progenitor cell differentiation [GO:0002244]; inner ear morphogenesis [GO:0042472]; neuromuscular process controlling balance [GO:0050885]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; regulation of fat cell differentiation [GO:0045598]; vestibular receptor cell morphogenesis [GO:0060116] GO:0002244; GO:0004725; GO:0016020; GO:0032421; GO:0042472; GO:0043235; GO:0045598; GO:0050885; GO:0050910; GO:0060116; GO:1990264 36260 XR_006391988.1 0 0 0 8 0 NA NA NA NA NA NA 36261 XM_044317226.1 2 7 0 2 13 NA NA NA NA NA NA 36262 XM_044317390.1 146 58 75 92 108 O43345 1.46e-41 Zinc finger protein 208 (Zinc finger protein 91-like) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0008270 36263 XM_044317390.1 146 58 75 92 108 O43345 8.31e-38 Zinc finger protein 208 (Zinc finger protein 91-like) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0008270 36264 XM_044327010.1 45 7 34 35 31 NA NA NA NA NA NA 36265 XM_044306758.1 224 137 140 172 181 NA NA NA NA NA NA 36266 XM_044321513.1 183 15 56 73 89 NA NA NA NA NA NA 36267 XM_029323723.2 128 31 26 70 119 NA NA NA NA NA NA 36268 XM_044325915.1 0 1 0 24 0 NA NA NA NA NA NA 36269 XM_044323916.1 144 41 95 166 0 Q91X17 1.74e-38 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Mus musculus (Mouse) antibacterial innate immune response [GO:0140367]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; autophagy [GO:0006914]; calcium ion homeostasis [GO:0055074]; cellular calcium ion homeostasis [GO:0006874]; cellular chloride ion homeostasis [GO:0030644]; cellular phosphate ion homeostasis [GO:0030643]; cellular response to unfolded protein [GO:0034620]; cellular sodium ion homeostasis [GO:0006883]; chaperone-mediated protein folding [GO:0061077]; chemical homeostasis [GO:0048878]; chloride ion homeostasis [GO:0055064]; citric acid secretion [GO:0046720]; collecting duct development [GO:0072044]; connective tissue replacement [GO:0097709]; creatinine homeostasis [GO:0097273]; defense response to Gram-negative bacterium [GO:0050829]; endoplasmic reticulum organization [GO:0007029]; gene expression [GO:0010467]; glomerular filtration [GO:0003094]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; ion homeostasis [GO:0050801]; juxtaglomerular apparatus development [GO:0072051]; kidney development [GO:0001822]; leukocyte cell-cell adhesion [GO:0007159]; lipid metabolic process [GO:0006629]; loop of Henle development [GO:0072070]; metanephric ascending thin limb development [GO:0072218]; metanephric distal convoluted tubule development [GO:0072221]; metanephric thick ascending limb development [GO:0072233]; micturition [GO:0060073]; multicellular organismal homeostasis [GO:0048871]; multicellular organismal response to stress [GO:0033555]; neutrophil migration [GO:1990266]; organ or tissue specific immune response [GO:0002251]; peptidyl-threonine phosphorylation [GO:0018107]; phosphate ion homeostasis [GO:0055062]; potassium ion homeostasis [GO:0055075]; protein localization to vacuole [GO:0072665]; protein phosphorylation [GO:0006468]; protein transport into plasma membrane raft [GO:0044861]; regulation of blood pressure [GO:0008217]; regulation of protein transport [GO:0051223]; regulation of urine volume [GO:0035809]; renal sodium ion absorption [GO:0070294]; renal urate salt excretion [GO:0097744]; renal water homeostasis [GO:0003091]; response to endoplasmic reticulum stress [GO:0034976]; response to lipopolysaccharide [GO:0032496]; response to unfolded protein [GO:0006986]; response to water deprivation [GO:0009414]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; sodium ion homeostasis [GO:0055078]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; ubiquitin-dependent ERAD pathway [GO:0030433]; urate transport [GO:0015747]; urea transmembrane transport [GO:0071918]; water homeostasis [GO:0030104] GO:0000922; GO:0001822; GO:0002251; GO:0003091; GO:0003094; GO:0005201; GO:0005509; GO:0005615; GO:0005783; GO:0005794; GO:0005886; GO:0005929; GO:0006468; GO:0006629; GO:0006874; GO:0006883; GO:0006914; GO:0006915; GO:0006954; GO:0006986; GO:0007029; GO:0007157; GO:0007159; GO:0008217; GO:0008380; GO:0009410; GO:0009414; GO:0009986; GO:0010467; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0018107; GO:0019864; GO:0030104; GO:0030433; GO:0030643; GO:0030644; GO:0031410; GO:0032496; GO:0033209; GO:0033555; GO:0034620; GO:0034976; GO:0035809; GO:0044861; GO:0045121; GO:0045177; GO:0046720; GO:0048871; GO:0048878; GO:0050801; GO:0050829; GO:0051223; GO:0055062; GO:0055064; GO:0055074; GO:0055075; GO:0055078; GO:0060073; GO:0060170; GO:0061077; GO:0070294; GO:0071918; GO:0072044; GO:0072051; GO:0072070; GO:0072218; GO:0072221; GO:0072233; GO:0072665; GO:0097190; GO:0097273; GO:0097709; GO:0097744; GO:0140367; GO:1990266 36270 XM_044315030.1 146 80 103 636 783 NA NA NA NA NA NA 36271 XM_044326911.1 732 814 443 676 534 Q14318 5.39e-79 Peptidyl-prolyl cis-trans isomerase FKBP8 (PPIase FKBP8) (EC 5.2.1.8) (38 kDa FK506-binding protein) (38 kDa FKBP) (FKBP-38) (hFKBP38) (FK506-binding protein 8) (FKBP-8) (FKBPR38) (Rotamase) Homo sapiens (Human) apoptotic process [GO:0006915]; BMP signaling pathway [GO:0030509]; camera-type eye development [GO:0043010]; dorsal/ventral neural tube patterning [GO:0021904]; intracellular signal transduction [GO:0035556]; multicellular organism growth [GO:0035264]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein phosphorylation [GO:0001933]; neuron fate specification [GO:0048665]; positive regulation of BMP signaling pathway [GO:0030513]; protein folding [GO:0006457]; protein localization to mitochondrion [GO:0070585]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of gene expression [GO:0010468]; smoothened signaling pathway [GO:0007224] GO:0001933; GO:0003755; GO:0005516; GO:0005739; GO:0005740; GO:0005783; GO:0005789; GO:0005829; GO:0006457; GO:0006915; GO:0007224; GO:0010468; GO:0012505; GO:0016020; GO:0021904; GO:0030509; GO:0030513; GO:0031966; GO:0032991; GO:0035264; GO:0035556; GO:0042802; GO:0043010; GO:0043066; GO:0044183; GO:0046872; GO:0048665; GO:0070585; GO:0097718; GO:1903146 36272 XM_044317116.1 55 15 7 4 44 NA NA NA NA NA NA 36273 XM_029325152.2 391 274 122 132 275 A7SLX5 0 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 (EC 2.5.1.108) (Diphthamide biosynthesis protein 1) (Diphtheria toxin resistance protein 1) (S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1) Nematostella vectensis (Starlet sea anemone) peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183] GO:0017183; GO:0032991; GO:0046872; GO:0051539; GO:0090560 36274 XM_044327230.1 9 0 7 0 5 Q96RW7 6.29e-25 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 36275 XM_044307014.1 0 1 0 7 0 NA NA NA NA NA NA 36276 XM_044319066.1 34 22 19 20 56 NA NA NA NA NA NA 36277 XM_044314202.1 40 0 6 17 22 Q96AY4 1.55e-63 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36278 XM_044314202.1 40 0 6 17 22 Q96AY4 7.54e-62 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36279 XM_044314202.1 40 0 6 17 22 Q96AY4 2.09e-61 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36280 XM_044314202.1 40 0 6 17 22 Q96AY4 1.33e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36281 XM_044314202.1 40 0 6 17 22 Q96AY4 8.2e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36282 XM_044314202.1 40 0 6 17 22 Q96AY4 6.57e-58 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36283 XM_044314202.1 40 0 6 17 22 Q96AY4 4.28e-56 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36284 XM_044314202.1 40 0 6 17 22 Q96AY4 1.84e-51 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36285 XM_044314202.1 40 0 6 17 22 Q96AY4 7.62e-49 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36286 XM_044314202.1 40 0 6 17 22 Q96AY4 5.43e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36287 XM_044329268.1 442 326 256 311 677 NA NA NA NA NA NA 36288 XM_029338692.2 1601 624 656 1466 444 NA NA NA NA NA NA 36289 XM_044316589.1 0 0 5 0 74 C3ZQF9 1.45e-25 QRFP-like peptide receptor Branchiostoma floridae (Florida lancelet) (Amphioxus) cellular response to peptide [GO:1901653]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:1901653 36290 XM_044311881.1 153 99 153 166 433 NA NA NA NA NA NA 36291 XM_044313013.1 32 14 14 40 9 NA NA NA NA NA NA 36292 XM_044325274.1 2 2 0 111 143 NA NA NA NA NA NA 36293 XM_029348428.2 908 1257 701 1050 765 P29687 5.68e-32 Ras-related protein Rab5 Nicotiana tabacum (Common tobacco) intracellular protein transport [GO:0006886] GO:0003924; GO:0005525; GO:0005768; GO:0005886; GO:0006886; GO:0012505; GO:0030139 36294 XM_029343462.2 6 7 0 0 0 NA NA NA NA NA NA 36295 XM_044312987.1 940 814 540 726 793 O95405 6.76e-170 Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Novel serine protease) (NSP) (Receptor activation anchor) (hSARA) (Smad anchor for receptor activation) Homo sapiens (Human) endocytosis [GO:0006897]; endosomal transport [GO:0016197]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0005545; GO:0005769; GO:0005829; GO:0006897; GO:0007179; GO:0016197; GO:0019904; GO:0031901; GO:0032991; GO:0043231; GO:0046872 36296 XM_044323384.1 0 0 0 0 7 Q9EP86 1.15e-21 Neuropeptide FF receptor 1 (G-protein coupled receptor 147) (RFamide-related peptide receptor OT7T022) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0005886; GO:0005929; GO:0007186; GO:0008188; GO:0042277 36297 XM_044321502.1 120 39 48 134 144 NA NA NA NA NA NA 36298 XR_006392838.1 60 7 19 22 8 NA NA NA NA NA NA 36299 XM_029323549.2 16281 20902 7667 9086 7104 NA NA NA NA NA NA 36300 XM_029349859.2 665 344 362 574 478 Q2HZX7 7.15e-122 Protein fuzzy homolog (Xfy) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cilium assembly [GO:0060271]; embryonic body morphogenesis [GO:0010172]; embryonic skeletal system morphogenesis [GO:0048704]; establishment of planar polarity [GO:0001736]; neural tube closure [GO:0001843]; protein transport [GO:0015031]; regulation of smoothened signaling pathway [GO:0008589]; vesicle-mediated transport [GO:0016192] GO:0001736; GO:0001843; GO:0005737; GO:0005856; GO:0008589; GO:0010172; GO:0015031; GO:0016192; GO:0042995; GO:0048704; GO:0060271 36301 XR_006394162.1 6 38 46 63 100 NA NA NA NA NA NA 36302 XM_029334129.2 212 122 303 111 528 NA NA NA NA NA NA 36303 XR_003824495.2 34 11 0 66 8 NA NA NA NA NA NA 36304 XM_044319868.1 8 0 93 25 134 Q8MIQ9 4.25e-126 P protein (Melanocyte-specific transporter protein) (Pink-eyed dilution protein homolog) Sus scrofa (Pig) lysosomal lumen pH elevation [GO:0035752]; melanin biosynthetic process [GO:0042438]; melanin biosynthetic process from tyrosine [GO:0006583]; melanocyte differentiation [GO:0030318] GO:0006583; GO:0030318; GO:0033162; GO:0035752; GO:0042438; GO:0061778 36305 XR_003823595.2 164 0 71 88 41 NA NA NA NA NA NA 36306 XM_044309597.1 0 20 0 0 0 NA NA NA NA NA NA 36307 XM_029356689.2 0 123 0 0 0 Q5ZHS1 0 Elongator complex protein 3 (EC 2.3.1.-) (tRNA uridine(34) acetyltransferase) Gallus gallus (Chicken) regulation of transcription by RNA polymerase II [GO:0006357]; tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation [GO:0002926]; tRNA wobble uridine modification [GO:0002098] GO:0000049; GO:0002098; GO:0002926; GO:0005634; GO:0005737; GO:0006357; GO:0008607; GO:0033588; GO:0046872; GO:0051539; GO:0106261 36308 XM_029333762.2 86 69 25 46 133 NA NA NA NA NA NA 36309 XM_044316926.1 0 3 0 0 8 NA NA NA NA NA NA 36310 XM_029335989.2 578 0 182 164 521 P49815 0 Tuberin (Tuberous sclerosis 2 protein) Homo sapiens (Human) anoikis [GO:0043276]; endocytosis [GO:0006897]; heart development [GO:0007507]; insulin-like growth factor receptor signaling pathway [GO:0048009]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of mitophagy [GO:1901525]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of Wnt signaling pathway [GO:0030178]; neural tube closure [GO:0001843]; positive chemotaxis [GO:0050918]; positive regulation of GTPase activity [GO:0043547]; positive regulation of macroautophagy [GO:0016239]; protein import into nucleus [GO:0006606]; protein kinase B signaling [GO:0043491]; protein localization [GO:0008104]; regulation of cell cycle [GO:0051726]; regulation of endocytosis [GO:0030100]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of small GTPase mediated signal transduction [GO:0051056]; vesicle-mediated transport [GO:0016192] GO:0001843; GO:0005096; GO:0005634; GO:0005737; GO:0005764; GO:0005794; GO:0005829; GO:0006469; GO:0006606; GO:0006897; GO:0007507; GO:0008104; GO:0008285; GO:0014067; GO:0014069; GO:0016020; GO:0016192; GO:0016239; GO:0019902; GO:0030100; GO:0030178; GO:0031267; GO:0032007; GO:0033596; GO:0042803; GO:0043276; GO:0043491; GO:0043547; GO:0046626; GO:0046627; GO:0048009; GO:0048471; GO:0050918; GO:0051056; GO:0051726; GO:0051879; GO:0051898; GO:1901525 36311 XM_029335989.2 578 0 182 164 521 P49815 4.89e-83 Tuberin (Tuberous sclerosis 2 protein) Homo sapiens (Human) anoikis [GO:0043276]; endocytosis [GO:0006897]; heart development [GO:0007507]; insulin-like growth factor receptor signaling pathway [GO:0048009]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of mitophagy [GO:1901525]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of Wnt signaling pathway [GO:0030178]; neural tube closure [GO:0001843]; positive chemotaxis [GO:0050918]; positive regulation of GTPase activity [GO:0043547]; positive regulation of macroautophagy [GO:0016239]; protein import into nucleus [GO:0006606]; protein kinase B signaling [GO:0043491]; protein localization [GO:0008104]; regulation of cell cycle [GO:0051726]; regulation of endocytosis [GO:0030100]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of small GTPase mediated signal transduction [GO:0051056]; vesicle-mediated transport [GO:0016192] GO:0001843; GO:0005096; GO:0005634; GO:0005737; GO:0005764; GO:0005794; GO:0005829; GO:0006469; GO:0006606; GO:0006897; GO:0007507; GO:0008104; GO:0008285; GO:0014067; GO:0014069; GO:0016020; GO:0016192; GO:0016239; GO:0019902; GO:0030100; GO:0030178; GO:0031267; GO:0032007; GO:0033596; GO:0042803; GO:0043276; GO:0043491; GO:0043547; GO:0046626; GO:0046627; GO:0048009; GO:0048471; GO:0050918; GO:0051056; GO:0051726; GO:0051879; GO:0051898; GO:1901525 36312 XR_006393993.1 279 305 181 645 458 NA NA NA NA NA NA 36313 XM_044324959.1 0 0 1 0 24 NA NA NA NA NA NA 36314 XM_029332627.2 686 648 470 502 297 Q8IUR6 2.56e-34 CREB3 regulatory factor (Luman recruitment factor) (LRF) Homo sapiens (Human) negative regulation of endoplasmic reticulum unfolded protein response [GO:1900102]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of intracellular transport [GO:0032388]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein transport [GO:0051222]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; response to endoplasmic reticulum stress [GO:0034976]; response to unfolded protein [GO:0006986] GO:0000122; GO:0000977; GO:0000981; GO:0001228; GO:0005634; GO:0005654; GO:0005737; GO:0006357; GO:0006986; GO:0016604; GO:0032388; GO:0034976; GO:0045732; GO:0045944; GO:0051222; GO:1900102 36315 XM_044317378.1 138 0 0 0 0 Q96AY4 2.82e-81 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36316 XM_044317378.1 138 0 0 0 0 Q96AY4 2.22e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36317 XM_044317378.1 138 0 0 0 0 Q96AY4 3.33e-70 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36318 XM_044317378.1 138 0 0 0 0 Q96AY4 1.3e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36319 XM_044317378.1 138 0 0 0 0 Q96AY4 2.71e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36320 XM_029328966.2 345 69 185 373 132 Q9D2E2 1.98e-85 Target of EGR1 protein 1 Mus musculus (Mouse) RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; snRNA 3'-end processing [GO:0034472] GO:0000175; GO:0003723; GO:0004535; GO:0005654; GO:0005730; GO:0005737; GO:0015030; GO:0016604; GO:0016607; GO:0017069; GO:0034472; GO:0046872; GO:0090503 36321 XM_044316433.1 22 5 21 135 14 NA NA NA NA NA NA 36322 XM_044313108.1 151 215 90 296 125 NA NA NA NA NA NA 36323 XM_029356006.2 1290 2910 1460 3240 3288 NA NA NA NA NA NA 36324 XR_006396035.1 43 42 19 38 16 NA NA NA NA NA NA 36325 XM_044321817.1 111 9 38 70 114 NA NA NA NA NA NA 36326 XM_029324986.2 1574 844 646 514 693 NA NA NA NA NA NA 36327 XM_044328234.1 14 21 0 0 0 Q9CS74 2.25e-149 Protein ecdysoneless homolog Mus musculus (Mouse) fibroblast proliferation [GO:0048144]; mRNA processing [GO:0006397]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; RNA splicing [GO:0008380] GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006397; GO:0008380; GO:0035035; GO:0045944; GO:0048144; GO:2000045 36328 XM_044307544.1 26 109 0 0 213 Q8R418 4.85e-165 Endoribonuclease Dicer (EC 3.1.26.3) (Double-strand-specific ribonuclease mDCR-1) Mus musculus (Mouse) anatomical structure development [GO:0048856]; angiogenesis [GO:0001525]; apoptotic DNA fragmentation [GO:0006309]; branching morphogenesis of an epithelial tube [GO:0048754]; cardiac muscle cell development [GO:0055013]; cardiac neural crest cell development involved in outflow tract morphogenesis [GO:0061309]; cartilage development [GO:0051216]; cell population proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; defense response to virus [GO:0051607]; digestive tract development [GO:0048565]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; epidermis morphogenesis [GO:0048730]; ganglion development [GO:0061548]; gene expression [GO:0010467]; global gene silencing by mRNA cleavage [GO:0098795]; hair follicle cell proliferation [GO:0071335]; hair follicle development [GO:0001942]; hair follicle morphogenesis [GO:0031069]; inner ear receptor cell development [GO:0060119]; intestinal epithelial cell development [GO:0060576]; lung development [GO:0030324]; meiotic spindle organization [GO:0000212]; miRNA processing [GO:0035196]; mRNA stabilization [GO:0048255]; multicellular organism growth [GO:0035264]; myoblast differentiation involved in skeletal muscle regeneration [GO:0014835]; negative regulation of gene expression [GO:0010629]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of Schwann cell proliferation [GO:0010626]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of tumor necrosis factor production [GO:0032720]; nerve development [GO:0021675]; neuron projection morphogenesis [GO:0048812]; NIK/NF-kappaB signaling [GO:0038061]; olfactory bulb interneuron differentiation [GO:0021889]; pericentric heterochromatin formation [GO:0031508]; peripheral nervous system myelin formation [GO:0032290]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904906]; positive regulation of establishment of endothelial barrier [GO:1903142]; positive regulation of gene expression [GO:0010628]; positive regulation of hepatic stellate cell proliferation [GO:1904899]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of myelination [GO:0031643]; positive regulation of Schwann cell differentiation [GO:0014040]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; post-embryonic development [GO:0009791]; pre-miRNA processing [GO:0031054]; regulation of cell cycle [GO:0051726]; regulation of enamel mineralization [GO:0070173]; regulation of epithelial cell differentiation [GO:0030856]; regulation of gene expression [GO:0010468]; regulation of inflammatory response [GO:0050727]; regulation of miRNA metabolic process [GO:2000628]; regulation of muscle cell apoptotic process [GO:0010660]; regulation of myelination [GO:0031641]; regulation of neurogenesis [GO:0050767]; regulation of neuron differentiation [GO:0045664]; regulation of Notch signaling pathway [GO:0008593]; regulation of odontogenesis of dentin-containing tooth [GO:0042487]; regulation of oligodendrocyte differentiation [GO:0048713]; regulation of protein phosphorylation [GO:0001932]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of RNA metabolic process [GO:0051252]; regulation of stem cell differentiation [GO:2000736]; regulation of viral genome replication [GO:0045069]; reproductive structure development [GO:0048608]; RISC complex assembly [GO:0070922]; RNA phosphodiester bond hydrolysis [GO:0090501]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; RNA processing [GO:0006396]; RNA-mediated post-transcriptional gene silencing [GO:0035194]; rRNA processing [GO:0006364]; siRNA processing [GO:0030422]; spermatogonial cell division [GO:0007284]; spinal cord motor neuron differentiation [GO:0021522]; spindle assembly [GO:0051225]; spleen development [GO:0048536]; stem cell population maintenance [GO:0019827]; trophectodermal cell proliferation [GO:0001834]; zygote asymmetric cell division [GO:0010070] GO:0000122; GO:0000212; GO:0001525; GO:0001834; GO:0001932; GO:0001942; GO:0003677; GO:0003723; GO:0003725; GO:0004386; GO:0004521; GO:0004525; GO:0004530; GO:0005524; GO:0005634; GO:0005737; GO:0005783; GO:0005793; GO:0005829; GO:0006309; GO:0006364; GO:0006396; GO:0007284; GO:0008283; GO:0008593; GO:0009791; GO:0010070; GO:0010467; GO:0010468; GO:0010595; GO:0010626; GO:0010628; GO:0010629; GO:0010660; GO:0014040; GO:0014835; GO:0016442; GO:0019827; GO:0019904; GO:0021522; GO:0021675; GO:0021889; GO:0021987; GO:0030324; GO:0030326; GO:0030422; GO:0030424; GO:0030425; GO:0030426; GO:0030856; GO:0031054; GO:0031069; GO:0031508; GO:0031641; GO:0031643; GO:0032290; GO:0032720; GO:0032967; GO:0035116; GO:0035194; GO:0035196; GO:0035197; GO:0035198; GO:0035264; GO:0038061; GO:0042487; GO:0045069; GO:0045589; GO:0045664; GO:0045944; GO:0046872; GO:0048255; GO:0048471; GO:0048536; GO:0048565; GO:0048608; GO:0048713; GO:0048730; GO:0048754; GO:0048812; GO:0048856; GO:0050727; GO:0050767; GO:0051216; GO:0051225; GO:0051252; GO:0051607; GO:0051726; GO:0055013; GO:0060119; GO:0060253; GO:0060576; GO:0061309; GO:0061548; GO:0070062; GO:0070173; GO:0070578; GO:0070883; GO:0070922; GO:0071335; GO:0090501; GO:0090502; GO:0098795; GO:0098978; GO:0099092; GO:1903142; GO:1904899; GO:1904906; GO:1905564; GO:2000628; GO:2000630; GO:2000736 36329 XM_044307544.1 26 109 0 0 213 Q8R418 1.36e-66 Endoribonuclease Dicer (EC 3.1.26.3) (Double-strand-specific ribonuclease mDCR-1) Mus musculus (Mouse) anatomical structure development [GO:0048856]; angiogenesis [GO:0001525]; apoptotic DNA fragmentation [GO:0006309]; branching morphogenesis of an epithelial tube [GO:0048754]; cardiac muscle cell development [GO:0055013]; cardiac neural crest cell development involved in outflow tract morphogenesis [GO:0061309]; cartilage development [GO:0051216]; cell population proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; defense response to virus [GO:0051607]; digestive tract development [GO:0048565]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; epidermis morphogenesis [GO:0048730]; ganglion development [GO:0061548]; gene expression [GO:0010467]; global gene silencing by mRNA cleavage [GO:0098795]; hair follicle cell proliferation [GO:0071335]; hair follicle development [GO:0001942]; hair follicle morphogenesis [GO:0031069]; inner ear receptor cell development [GO:0060119]; intestinal epithelial cell development [GO:0060576]; lung development [GO:0030324]; meiotic spindle organization [GO:0000212]; miRNA processing [GO:0035196]; mRNA stabilization [GO:0048255]; multicellular organism growth [GO:0035264]; myoblast differentiation involved in skeletal muscle regeneration [GO:0014835]; negative regulation of gene expression [GO:0010629]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of Schwann cell proliferation [GO:0010626]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of tumor necrosis factor production [GO:0032720]; nerve development [GO:0021675]; neuron projection morphogenesis [GO:0048812]; NIK/NF-kappaB signaling [GO:0038061]; olfactory bulb interneuron differentiation [GO:0021889]; pericentric heterochromatin formation [GO:0031508]; peripheral nervous system myelin formation [GO:0032290]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904906]; positive regulation of establishment of endothelial barrier [GO:1903142]; positive regulation of gene expression [GO:0010628]; positive regulation of hepatic stellate cell proliferation [GO:1904899]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of myelination [GO:0031643]; positive regulation of Schwann cell differentiation [GO:0014040]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; post-embryonic development [GO:0009791]; pre-miRNA processing [GO:0031054]; regulation of cell cycle [GO:0051726]; regulation of enamel mineralization [GO:0070173]; regulation of epithelial cell differentiation [GO:0030856]; regulation of gene expression [GO:0010468]; regulation of inflammatory response [GO:0050727]; regulation of miRNA metabolic process [GO:2000628]; regulation of muscle cell apoptotic process [GO:0010660]; regulation of myelination [GO:0031641]; regulation of neurogenesis [GO:0050767]; regulation of neuron differentiation [GO:0045664]; regulation of Notch signaling pathway [GO:0008593]; regulation of odontogenesis of dentin-containing tooth [GO:0042487]; regulation of oligodendrocyte differentiation [GO:0048713]; regulation of protein phosphorylation [GO:0001932]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of RNA metabolic process [GO:0051252]; regulation of stem cell differentiation [GO:2000736]; regulation of viral genome replication [GO:0045069]; reproductive structure development [GO:0048608]; RISC complex assembly [GO:0070922]; RNA phosphodiester bond hydrolysis [GO:0090501]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; RNA processing [GO:0006396]; RNA-mediated post-transcriptional gene silencing [GO:0035194]; rRNA processing [GO:0006364]; siRNA processing [GO:0030422]; spermatogonial cell division [GO:0007284]; spinal cord motor neuron differentiation [GO:0021522]; spindle assembly [GO:0051225]; spleen development [GO:0048536]; stem cell population maintenance [GO:0019827]; trophectodermal cell proliferation [GO:0001834]; zygote asymmetric cell division [GO:0010070] GO:0000122; GO:0000212; GO:0001525; GO:0001834; GO:0001932; GO:0001942; GO:0003677; GO:0003723; GO:0003725; GO:0004386; GO:0004521; GO:0004525; GO:0004530; GO:0005524; GO:0005634; GO:0005737; GO:0005783; GO:0005793; GO:0005829; GO:0006309; GO:0006364; GO:0006396; GO:0007284; GO:0008283; GO:0008593; GO:0009791; GO:0010070; GO:0010467; GO:0010468; GO:0010595; GO:0010626; GO:0010628; GO:0010629; GO:0010660; GO:0014040; GO:0014835; GO:0016442; GO:0019827; GO:0019904; GO:0021522; GO:0021675; GO:0021889; GO:0021987; GO:0030324; GO:0030326; GO:0030422; GO:0030424; GO:0030425; GO:0030426; GO:0030856; GO:0031054; GO:0031069; GO:0031508; GO:0031641; GO:0031643; GO:0032290; GO:0032720; GO:0032967; GO:0035116; GO:0035194; GO:0035196; GO:0035197; GO:0035198; GO:0035264; GO:0038061; GO:0042487; GO:0045069; GO:0045589; GO:0045664; GO:0045944; GO:0046872; GO:0048255; GO:0048471; GO:0048536; GO:0048565; GO:0048608; GO:0048713; GO:0048730; GO:0048754; GO:0048812; GO:0048856; GO:0050727; GO:0050767; GO:0051216; GO:0051225; GO:0051252; GO:0051607; GO:0051726; GO:0055013; GO:0060119; GO:0060253; GO:0060576; GO:0061309; GO:0061548; GO:0070062; GO:0070173; GO:0070578; GO:0070883; GO:0070922; GO:0071335; GO:0090501; GO:0090502; GO:0098795; GO:0098978; GO:0099092; GO:1903142; GO:1904899; GO:1904906; GO:1905564; GO:2000628; GO:2000630; GO:2000736 36330 XM_029352618.2 105 0 57 0 0 Q5NDL0 0 EGF domain-specific O-linked N-acetylglucosamine transferase (EC 2.4.1.255) (Extracellular O-linked N-acetylglucosamine transferase) Rattus norvegicus (Rat) protein O-GlcNAcylation via threonine [GO:0097370]; protein O-linked glycosylation [GO:0006493] GO:0005788; GO:0006493; GO:0008375; GO:0016262; GO:0016757; GO:0097363; GO:0097370 36331 XM_029353673.2 0 0 0 87 13 P25931 1.45e-23 RYamide receptor (Neuropeptide Y-like receptor) (NPY-R) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218] GO:0001653; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0016020 36332 XM_044323973.1 864 1994 667 1703 1520 NA NA NA NA NA NA 36333 XM_044313236.1 341 369 170 273 217 P54315 1.3e-63 Inactive pancreatic lipase-related protein 1 (PL-RP1) Homo sapiens (Human) lipid metabolic process [GO:0006629] GO:0004806; GO:0005509; GO:0005576; GO:0006629 36334 XM_029357570.2 4852 4126 3948 4254 4875 P51570 2.45e-150 Galactokinase (EC 2.7.1.6) (Galactose kinase) Homo sapiens (Human) galactitol metabolic process [GO:0019402]; galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]; glycolytic process from galactose [GO:0061623] GO:0004335; GO:0005524; GO:0005534; GO:0005737; GO:0005829; GO:0006012; GO:0016020; GO:0019388; GO:0019402; GO:0033499; GO:0061623; GO:0070062 36335 XM_029337724.2 199 172 151 105 178 E7F5E1 6.86e-97 Centrosomal protein of 162 kDa (Cep162) Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; heart looping [GO:0001947] GO:0001947; GO:0005813; GO:0005814; GO:0005879; GO:0060271 36336 XR_006395587.1 0 0 0 63 0 Q20191 2.38e-51 Zinc metalloproteinase nas-13 (EC 3.4.24.-) (Nematode astacin 13) Caenorhabditis elegans proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0006508; GO:0008270 36337 XM_029336170.2 215 309 151 117 223 Q5U3U4 1.44e-27 Cytidine and dCMP deaminase domain-containing protein 1 (EC 3.5.4.5) (Cytidine deaminase) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0004126; GO:0008270 36338 XM_029336694.2 1724 1915 739 2253 2181 Q9STG6 4.74e-56 Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase) (dUTP-pyrophosphatase-like 1) (AtDUT1) Arabidopsis thaliana (Mouse-ear cress) DNA repair [GO:0006281]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081] GO:0000287; GO:0004170; GO:0006226; GO:0006281; GO:0042802; GO:0046081 36339 XM_029334870.2 0 0 0 22 7 NA NA NA NA NA NA 36340 XR_006394429.1 10424 4666 2627 7376 6485 Q9NQX0 2.16e-58 Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.361) (PR domain zinc finger protein 6) (PR domain-containing protein 6) Homo sapiens (Human) chromatin organization [GO:0006325]; histone methylation [GO:0016571]; negative regulation of smooth muscle cell differentiation [GO:0051151]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of gene expression [GO:0010468] GO:0000122; GO:0005634; GO:0006325; GO:0010468; GO:0016571; GO:0022008; GO:0042802; GO:0046872; GO:0051151; GO:0140944 36341 XR_006394429.1 10424 4666 2627 7376 6485 Q9NQX0 2.97e-44 Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.361) (PR domain zinc finger protein 6) (PR domain-containing protein 6) Homo sapiens (Human) chromatin organization [GO:0006325]; histone methylation [GO:0016571]; negative regulation of smooth muscle cell differentiation [GO:0051151]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of gene expression [GO:0010468] GO:0000122; GO:0005634; GO:0006325; GO:0010468; GO:0016571; GO:0022008; GO:0042802; GO:0046872; GO:0051151; GO:0140944 36342 XR_006394429.1 10424 4666 2627 7376 6485 Q9NQX0 2.07e-36 Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.361) (PR domain zinc finger protein 6) (PR domain-containing protein 6) Homo sapiens (Human) chromatin organization [GO:0006325]; histone methylation [GO:0016571]; negative regulation of smooth muscle cell differentiation [GO:0051151]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of gene expression [GO:0010468] GO:0000122; GO:0005634; GO:0006325; GO:0010468; GO:0016571; GO:0022008; GO:0042802; GO:0046872; GO:0051151; GO:0140944 36343 XM_044329089.1 18 12 10 2 94 NA NA NA NA NA NA 36344 XM_029329753.2 0 0 0 490 0 Q9R0X0 3.88e-58 Mediator of RNA polymerase II transcription subunit 20 (Mediator complex subunit 20) (TRF-proximal protein homolog) Mus musculus (Mouse) positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; protein ubiquitination [GO:0016567]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA polymerase II preinitiation complex assembly [GO:0051123]; skeletal muscle cell differentiation [GO:0035914] GO:0000151; GO:0003713; GO:0005634; GO:0005654; GO:0006357; GO:0016567; GO:0016592; GO:0032968; GO:0035914; GO:0051123; GO:0060261; GO:0061630; GO:0070847 36345 XM_029357166.2 2722 2320 1002 2626 2768 NA NA NA NA NA NA 36346 XM_029339263.2 0 0 19 82 0 Q9N2B7 4.57e-39 5-hydroxytryptamine receptor 1B (5-HT-1B) (5-HT1B) (Serotonin receptor 1B) Gorilla gorilla gorilla (Western lowland gorilla) adenylate cyclase-inhibiting serotonin receptor signaling pathway [GO:0007198]; behavior [GO:0007610]; bone remodeling [GO:0046849]; cellular response to alkaloid [GO:0071312]; cellular response to xenobiotic stimulus [GO:0071466]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; negative regulation of serotonin secretion [GO:0014063]; regulation of behavior [GO:0050795]; vasoconstriction [GO:0042310] GO:0004993; GO:0005886; GO:0007187; GO:0007198; GO:0007268; GO:0007610; GO:0014063; GO:0030425; GO:0030594; GO:0042310; GO:0045202; GO:0046849; GO:0050795; GO:0051378; GO:0071312; GO:0071466 36347 XM_044312389.1 9 0 13 0 0 NA NA NA NA NA NA 36348 XM_029335120.2 669 744 236 516 338 Q9H773 1.1e-51 dCTP pyrophosphatase 1 (EC 3.6.1.12) (Deoxycytidine-triphosphatase 1) (dCTPase 1) (RS21C6) (XTP3-transactivated gene A protein) Homo sapiens (Human) dCTP catabolic process [GO:0006253]; DNA protection [GO:0042262]; nucleoside triphosphate catabolic process [GO:0009143] GO:0000287; GO:0005634; GO:0005654; GO:0005739; GO:0005829; GO:0006253; GO:0009143; GO:0032556; GO:0042262; GO:0042802; GO:0047429; GO:0047840 36349 XM_029352155.2 3149 3196 1889 3199 2317 A8MY62 1.94e-47 Putative beta-lactamase-like 1 Homo sapiens (Human) NA NA 36350 XM_029358175.2 499 39 209 0 664 Q6REY9 1.37e-97 Rho GTPase-activating protein 20 (RA and RhoGAP domain-containing protein) (RARhoGAP) (Rho-type GTPase-activating protein 20) Rattus norvegicus (Rat) regulation of Rho protein signal transduction [GO:0035023]; signal transduction [GO:0007165] GO:0005096; GO:0007165; GO:0031267; GO:0035023 36351 XM_029353479.2 196 285 130 232 422 Q5SSI6 7.33e-117 U3 small nucleolar RNA-associated protein 18 homolog (WD repeat-containing protein 50) Mus musculus (Mouse) rRNA processing [GO:0006364] GO:0005634; GO:0005654; GO:0005730; GO:0006364; GO:0031965; GO:0032040; GO:0034388 36352 XR_003825942.2 1816 2192 838 900 1454 NA NA NA NA NA NA 36353 XM_029348502.2 0 0 0 12 0 D3YXG0 1.27e-24 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 36354 XM_029348502.2 0 0 0 12 0 D3YXG0 9e-22 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 36355 XR_006394214.1 0 2 0 96 30 NA NA NA NA NA NA 36356 XM_029350369.2 847 1101 678 876 829 NA NA NA NA NA NA 36357 XR_006396895.1 222 103 58 54 267 NA NA NA NA NA NA 36358 XM_029339628.2 2601 3392 1251 2136 1417 Q9FR44 1.24e-95 Phosphoethanolamine N-methyltransferase 1 (AtNMT1) (PEAMT 1) (EC 2.1.1.103) (Protein XIPOTL 1) Arabidopsis thaliana (Mouse-ear cress) choline biosynthetic process [GO:0042425]; methylation [GO:0032259]; phosphatidylcholine biosynthetic process [GO:0006656]; pollen development [GO:0009555]; pollen tube growth [GO:0009860]; pollen tube guidance [GO:0010183]; post-embryonic root development [GO:0048528]; unidimensional cell growth [GO:0009826] GO:0000234; GO:0005737; GO:0006656; GO:0008168; GO:0009555; GO:0009826; GO:0009860; GO:0010183; GO:0032259; GO:0042425; GO:0048528; GO:0052667 36359 XR_003823573.2 54 36 45 91 55 NA NA NA NA NA NA 36360 XM_044319062.1 0 0 1 0 27 NA NA NA NA NA NA 36361 XM_044326921.1 9 13 436 6 196 NA NA NA NA NA NA 36362 XM_044311453.1 4 6 616 367 13 NA NA NA NA NA NA 36363 XM_044307195.1 196 146 165 169 228 NA NA NA NA NA NA 36364 XM_029342548.2 0 0 0 291 0 Q08257 3.28e-125 Quinone oxidoreductase (EC 1.6.5.5) (NADPH:quinone reductase) (Zeta-crystallin) Homo sapiens (Human) protein homotetramerization [GO:0051289]; visual perception [GO:0007601]; xenobiotic catabolic process [GO:0042178] GO:0003730; GO:0003960; GO:0005829; GO:0007601; GO:0008270; GO:0042178; GO:0042802; GO:0051289; GO:0070062; GO:0070402 36365 XR_006396187.1 36 3 2 3 16 NA NA NA NA NA NA 36366 XM_029340438.2 730 658 383 501 630 Q6DIH3 0 DNA replication licensing factor mcm2 (EC 3.6.4.12) (Minichromosome maintenance protein 2) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell cycle [GO:0007049]; DNA replication initiation [GO:0006270]; DNA unwinding involved in DNA replication [GO:0006268]; negative regulation of DNA helicase activity [GO:1905775]; regulation of DNA-templated DNA replication initiation [GO:0030174] GO:0000785; GO:0003677; GO:0004386; GO:0005524; GO:0006268; GO:0006270; GO:0007049; GO:0016887; GO:0030174; GO:0042555; GO:0046872; GO:0071162; GO:1905775 36367 XR_006397020.1 82 39 11 0 0 NA NA NA NA NA NA 36368 XM_029332704.2 130 0 226 11 313 NA NA NA NA NA NA 36369 XM_029331438.2 186 192 212 275 161 Q70VZ7 3.41e-62 2-acylglycerol O-acyltransferase 1 (EC 2.3.1.22) (Acyl CoA:monoacylglycerol acyltransferase 1) (MGAT1) (Monoacylglycerol O-acyltransferase 1) Bos taurus (Bovine) diacylglycerol biosynthetic process [GO:0006651]; glycerol metabolic process [GO:0006071]; lipid metabolic process [GO:0006629]; triglyceride biosynthetic process [GO:0019432] GO:0003846; GO:0004144; GO:0005789; GO:0006071; GO:0006629; GO:0006651; GO:0008374; GO:0019432 36370 XM_029337981.2 253 160 210 679 310 Q08881 1.93e-33 Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) Homo sapiens (Human) activation of phospholipase C activity [GO:0007202]; adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular defense response [GO:0006968]; gamma-delta T cell activation [GO:0046629]; intracellular signal transduction [GO:0035556]; NK T cell differentiation [GO:0001865]; positive regulation of cytokine production [GO:0001819]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell receptor signaling pathway [GO:0050852] GO:0001819; GO:0001865; GO:0002250; GO:0004713; GO:0004715; GO:0005524; GO:0005634; GO:0005829; GO:0005886; GO:0005911; GO:0006968; GO:0007165; GO:0007202; GO:0035556; GO:0042110; GO:0046629; GO:0046872; GO:0050852; GO:0050853 36371 XM_044318157.1 1470 2148 1516 1394 1777 NA NA NA NA NA NA 36372 XM_044312263.1 75 0 9 7 8 NA NA NA NA NA NA 36373 XM_029330156.2 19 4 48 15 32 P29508 2.3e-79 Serpin B3 (Protein T4-A) (Squamous cell carcinoma antigen 1) (SCCA-1) Homo sapiens (Human) autocrine signaling [GO:0035425]; negative regulation of catalytic activity [GO:0043086]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; paracrine signaling [GO:0038001]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endopeptidase activity [GO:0010950]; positive regulation of epithelial to mesenchymal transition [GO:0010718] GO:0001618; GO:0002020; GO:0004867; GO:0004869; GO:0005576; GO:0005615; GO:0005634; GO:0005737; GO:0008284; GO:0010466; GO:0010718; GO:0010950; GO:0010951; GO:0030335; GO:0031410; GO:0031982; GO:0035425; GO:0035578; GO:0038001; GO:0043086; GO:0043508; GO:0045861; GO:0070062 36374 XM_029344693.2 0 0 0 0 87 Q502B3 7.26e-110 UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2 (Beta-1,3-GalNAc-T2) (EC 2.4.1.313) (Beta-1,3-N-acetylgalactosaminyltransferase II) Danio rerio (Zebrafish) (Brachydanio rerio) protein glycosylation [GO:0006486]; protein O-linked glycosylation [GO:0006493] GO:0000139; GO:0005783; GO:0006486; GO:0006493; GO:0008194; GO:0008376; GO:0016757 36375 XM_029346320.2 1552 1337 1031 1922 1718 O95071 5.21e-54 E3 ubiquitin-protein ligase UBR5 (EC 2.3.2.26) (E3 ubiquitin-protein ligase, HECT domain-containing 1) (HECT-type E3 ubiquitin transferase UBR5) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA repair-dependent chromatin remodeling [GO:0140861]; negative regulation of double-strand break repair [GO:2000780]; negative regulation of histone H2A K63-linked ubiquitination [GO:1901315]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of protein import into nucleus [GO:0042307]; progesterone receptor signaling pathway [GO:0050847]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; regulation of double-strand break repair [GO:2000779] GO:0000209; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006281; GO:0006974; GO:0008270; GO:0010628; GO:0016020; GO:0032991; GO:0034450; GO:0042307; GO:0043130; GO:0048471; GO:0050847; GO:0061630; GO:0070936; GO:0090263; GO:0140861; GO:1901315; GO:2000779; GO:2000780 36376 XM_044308059.1 427 114 65 143 179 Q1PSW8 2.34e-38 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (mLin41) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Mus musculus (Mouse) 3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to organic substance [GO:0071310]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA processing [GO:0035196]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; post-transcriptional regulation of gene expression [GO:0010608]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein metabolic process [GO:0051246]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0001843; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0010608; GO:0017148; GO:0021915; GO:0030371; GO:0035196; GO:0035198; GO:0035278; GO:0043161; GO:0051246; GO:0051865; GO:0060964; GO:0061158; GO:0061630; GO:0071310; GO:0072089; GO:2000177; GO:2000637 36377 XM_044325561.1 104 49 62 31 13 NA NA NA NA NA NA 36378 XM_044306761.1 34 16 73 66 47 NA NA NA NA NA NA 36379 XM_029347017.2 0 0 0 0 10 NA NA NA NA NA NA 36380 XM_044328690.1 0 23 8 0 23 P46197 0 Atrial natriuretic peptide receptor 2 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type B) (ANP-B) (ANPR-B) (NPR-B) (Guanylate cyclase B) (GC-B) Bos taurus (Bovine) activation of meiosis involved in egg activation [GO:0060466]; axonogenesis involved in innervation [GO:0060385]; blood circulation [GO:0008015]; blood vessel remodeling [GO:0001974]; c-di-GMP signaling [GO:0061939]; cellular response to cGMP [GO:0071321]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to peptide [GO:1901653]; cGMP biosynthetic process [GO:0006182]; chemical synaptic transmission [GO:0007268]; chondrocyte differentiation [GO:0002062]; chondrocyte proliferation [GO:0035988]; chromosome organization [GO:0051276]; collateral sprouting [GO:0048668]; cumulus cell differentiation [GO:0001549]; digestive tract morphogenesis [GO:0048546]; endochondral ossification [GO:0001958]; epidermal growth factor receptor signaling pathway [GO:0007173]; execution phase of apoptosis [GO:0097194]; female genitalia development [GO:0030540]; gastric emptying [GO:0035483]; genitalia morphogenesis [GO:0035112]; growth plate cartilage development [GO:0003417]; limb morphogenesis [GO:0035108]; lymph vessel development [GO:0001945]; MAPK cascade [GO:0000165]; meiotic cell cycle process involved in oocyte maturation [GO:1903537]; multicellular organism growth [GO:0035264]; negative regulation of meiotic cell cycle [GO:0051447]; negative regulation of oocyte maturation [GO:1900194]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; post-anal tail morphogenesis [GO:0036342]; protein phosphorylation [GO:0006468]; receptor guanylyl cyclase signaling pathway [GO:0007168]; response to fibroblast growth factor [GO:0071774]; response to luteinizing hormone [GO:0034699]; response to salt [GO:1902074]; sensory perception of sound [GO:0007605]; signal transduction [GO:0007165]; smooth muscle tissue development [GO:0048745]; spermatogenesis [GO:0007283]; startle response [GO:0001964]; vacuole organization [GO:0007033]; vascular wound healing [GO:0061042]; vasculogenesis [GO:0001570]; vestibulocochlear nerve maturation [GO:0021647]; white fat cell differentiation [GO:0050872] GO:0000165; GO:0001549; GO:0001570; GO:0001653; GO:0001945; GO:0001958; GO:0001964; GO:0001974; GO:0002062; GO:0003417; GO:0004383; GO:0004672; GO:0005524; GO:0005525; GO:0005634; GO:0005737; GO:0005886; GO:0005929; GO:0006182; GO:0006468; GO:0007033; GO:0007165; GO:0007168; GO:0007173; GO:0007268; GO:0007283; GO:0007605; GO:0008015; GO:0016941; GO:0017046; GO:0019228; GO:0021647; GO:0030540; GO:0034699; GO:0035108; GO:0035112; GO:0035264; GO:0035483; GO:0035988; GO:0036342; GO:0042802; GO:0043005; GO:0045202; GO:0048546; GO:0048668; GO:0048745; GO:0050872; GO:0051276; GO:0051402; GO:0051447; GO:0060385; GO:0060466; GO:0061042; GO:0061939; GO:0071321; GO:0071774; GO:0097011; GO:0097194; GO:1900194; GO:1901653; GO:1902074; GO:1903537 36381 XR_006398076.1 17 0 29 0 28 NA NA NA NA NA NA 36382 XM_029343512.2 75 172 43 56 50 NA NA NA NA NA NA 36383 XM_044320750.1 329 131 112 234 304 Q8N5T2 1.51e-169 TBC1 domain family member 19 Homo sapiens (Human) NA GO:0005096 36384 XM_029340234.2 55 66 47 100 0 O19094 7.5e-165 Peroxisomal carnitine O-octanoyltransferase (COT) (EC 2.3.1.137) Bos taurus (Bovine) carnitine metabolic process [GO:0009437]; coenzyme A metabolic process [GO:0015936]; fatty acid beta-oxidation [GO:0006635]; fatty acid metabolic process [GO:0006631]; generation of precursor metabolites and energy [GO:0006091]; medium-chain fatty acid metabolic process [GO:0051791] GO:0005777; GO:0006091; GO:0006631; GO:0006635; GO:0008458; GO:0009437; GO:0015936; GO:0051791 36385 XM_044315258.1 0 0 36 32 103 Q7RTR2 4.88e-53 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 36386 XM_044315258.1 0 0 36 32 103 Q7RTR2 1.35e-52 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 36387 XM_044315258.1 0 0 36 32 103 Q7RTR2 2.53e-44 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 36388 XM_044327791.1 0 0 8 0 0 NA NA NA NA NA NA 36389 XR_006396498.1 22 0 6 11 18 NA NA NA NA NA NA 36390 XR_006395731.1 281 188 171 154 265 NA NA NA NA NA NA 36391 XR_006396908.1 0 164 58 266 160 NA NA NA NA NA NA 36392 XM_029330022.2 626 1156 699 544 419 Q04832 1.11e-41 DNA-binding protein HEXBP (Hexamer-binding protein) Leishmania major NA GO:0003677; GO:0005634; GO:0008270 36393 XM_029330022.2 626 1156 699 544 419 Q04832 1.08e-28 DNA-binding protein HEXBP (Hexamer-binding protein) Leishmania major NA GO:0003677; GO:0005634; GO:0008270 36394 XM_029330022.2 626 1156 699 544 419 Q04832 1.17e-28 DNA-binding protein HEXBP (Hexamer-binding protein) Leishmania major NA GO:0003677; GO:0005634; GO:0008270 36395 XM_029330022.2 626 1156 699 544 419 Q04832 3.34e-26 DNA-binding protein HEXBP (Hexamer-binding protein) Leishmania major NA GO:0003677; GO:0005634; GO:0008270 36396 XR_006397366.1 34 26 10 29 21 NA NA NA NA NA NA 36397 XM_044329094.1 9 0 0 5 11 NA NA NA NA NA NA 36398 XM_044324150.1 187 111 168 187 127 Q96AY4 7.41e-153 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36399 XM_044324150.1 187 111 168 187 127 Q96AY4 6e-102 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36400 XM_044324150.1 187 111 168 187 127 Q96AY4 3.76e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36401 XM_029356275.2 0 0 0 0 6 Q6P832 0 Glycine amidinotransferase, mitochondrial (EC 2.1.4.1) (L-arginine:glycine amidinotransferase) (Transamidinase) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) creatine biosynthetic process [GO:0006601] GO:0005743; GO:0006601; GO:0015068 36402 XM_029332262.2 72 37 21 119 88 O43854 3.32e-23 EGF-like repeat and discoidin I-like domain-containing protein 3 (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1) Homo sapiens (Human) cell adhesion [GO:0007155]; positive regulation of cell-substrate adhesion [GO:0010811] GO:0005178; GO:0005509; GO:0007155; GO:0010811; GO:0062023; GO:0070062; GO:1903561 36403 XM_044308486.1 2 0 9 47 5 NA NA NA NA NA NA 36404 XM_044327490.1 50 0 0 8 0 NA NA NA NA NA NA 36405 XM_029351349.2 0 26 0 0 0 Q6NS23 5.14e-135 tRNA (guanine(10)-N2)-methyltransferase homolog (EC 2.1.1.-) (tRNA guanosine-2'-O-methyltransferase TRM11 homolog) Xenopus laevis (African clawed frog) RNA methylation [GO:0001510]; tRNA processing [GO:0008033] GO:0000049; GO:0001510; GO:0008033; GO:0008168 36406 XM_044314099.1 320 351 223 259 233 P48147 0 Prolyl endopeptidase (PE) (EC 3.4.21.26) (Post-proline cleaving enzyme) Homo sapiens (Human) proteolysis [GO:0006508] GO:0004252; GO:0005634; GO:0005737; GO:0005829; GO:0006508; GO:0008236; GO:0016020; GO:0070012 36407 XM_029336756.2 1047 900 372 562 554 P82343 2.04e-147 N-acylglucosamine 2-epimerase (AGE) (EC 5.1.3.8) (GlcNAc 2-epimerase) (N-acetyl-D-glucosamine 2-epimerase) (Renin-binding protein) (RnBP) Mus musculus (Mouse) carbohydrate metabolic process [GO:0005975]; N-acetylglucosamine metabolic process [GO:0006044]; N-acetylmannosamine metabolic process [GO:0006051]; N-acetylneuraminate catabolic process [GO:0019262]; negative regulation of catalytic activity [GO:0043086]; negative regulation of endopeptidase activity [GO:0010951] GO:0004857; GO:0005524; GO:0005975; GO:0006044; GO:0006051; GO:0010951; GO:0017076; GO:0019262; GO:0030414; GO:0042802; GO:0043086; GO:0050121 36408 XM_029327107.2 4 0 0 39 4 NA NA NA NA NA NA 36409 XM_044310706.1 1 0 0 1 15 NA NA NA NA NA NA 36410 XM_029335574.2 480 278 180 555 133 Q9CQF6 2.04e-84 L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase (EC 2.7.8.7) (4'-phosphopantetheinyl transferase) (Alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase) (AASD-PPT) Mus musculus (Mouse) 10-formyltetrahydrofolate catabolic process [GO:0009258]; lysine biosynthetic process via aminoadipic acid [GO:0019878]; protein maturation [GO:0051604] GO:0000287; GO:0005829; GO:0008897; GO:0009258; GO:0019878; GO:0051604 36411 XM_029335460.2 0 208 0 0 0 Q8JZP9 4.02e-54 GAS2-like protein 1 (Growth arrest-specific protein 2-like 1) Mus musculus (Mouse) actin crosslink formation [GO:0051764]; cellular response to starvation [GO:0009267]; cellular response to thyroid hormone stimulus [GO:0097067]; microtubule bundle formation [GO:0001578]; negative regulation of cell growth [GO:0030308]; negative regulation of erythrocyte differentiation [GO:0045647]; negative regulation of gene expression [GO:0010629]; negative regulation of microtubule depolymerization [GO:0007026]; protein localization to microtubule plus-end [GO:1904825]; regulation of cell cycle [GO:0051726]; regulation of microtubule polymerization or depolymerization [GO:0031110] GO:0001578; GO:0001725; GO:0005737; GO:0005874; GO:0005884; GO:0007026; GO:0008017; GO:0008093; GO:0009267; GO:0010629; GO:0030308; GO:0031110; GO:0035371; GO:0045647; GO:0046966; GO:0051015; GO:0051726; GO:0051764; GO:0097067; GO:1904825 36412 XR_006391870.1 336 45 270 28 1017 NA NA NA NA NA NA 36413 XM_029336358.2 127 88 116 121 162 Q9JJK3 5.79e-102 Peroxisomal biogenesis factor 3 (Peroxin-3) (Peroxisomal assembly protein PEX3) Cricetulus longicaudatus (Long-tailed dwarf hamster) (Chinese hamster) peroxisome organization [GO:0007031]; protein import into peroxisome membrane [GO:0045046] GO:0005777; GO:0005778; GO:0007031; GO:0045046 36414 XM_029348385.2 235 284 49 143 62 NA NA NA NA NA NA 36415 XM_044316523.1 12 17 60 29 70 NA NA NA NA NA NA 36416 XR_003823007.2 8 1 2 5 12 Q6P686 1.47e-23 Osteoclast-stimulating factor 1 Rattus norvegicus (Rat) signal transduction [GO:0007165] GO:0005737; GO:0007165; GO:0017124 36417 XM_044315751.1 4 0 0 0 9 NA NA NA NA NA NA 36418 XM_029334328.2 473 447 34 1245 198 NA NA NA NA NA NA 36419 XM_029331222.2 1368 447 532 1330 2016 NA NA NA NA NA NA 36420 XR_006393920.1 41 2 25 5 151 NA NA NA NA NA NA 36421 XM_029349264.2 181 16 11 13 247 NA NA NA NA NA NA 36422 XM_044321200.1 1653 1020 705 1466 1245 Q91ZW3 0 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.4.-) (Sucrose nonfermenting protein 2 homolog) (mSnf2h) Mus musculus (Mouse) cellular response to leukemia inhibitory factor [GO:1990830]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; DNA repair [GO:0006281]; DNA-templated transcription initiation [GO:0006352]; heterochromatin formation [GO:0031507]; negative regulation of mitotic chromosome condensation [GO:1905213]; negative regulation of transcription by RNA polymerase I [GO:0016479]; nucleosome assembly [GO:0006334]; positive regulation of DNA replication [GO:0045740]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of histone methylation [GO:0031062]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription by RNA polymerase III [GO:0045945]; rDNA heterochromatin formation [GO:0000183]; regulation of DNA methylation [GO:0044030]; regulation of DNA replication [GO:0006275]; regulation of DNA-templated transcription [GO:0006355]; regulation of response to DNA damage stimulus [GO:2001020] GO:0000183; GO:0000793; GO:0001650; GO:0003677; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0005677; GO:0005721; GO:0005730; GO:0006275; GO:0006281; GO:0006325; GO:0006334; GO:0006338; GO:0006352; GO:0006355; GO:0008094; GO:0008623; GO:0016479; GO:0016589; GO:0016590; GO:0016887; GO:0031010; GO:0031062; GO:0031065; GO:0031213; GO:0031491; GO:0031507; GO:0035066; GO:0035861; GO:0042393; GO:0043596; GO:0044030; GO:0045740; GO:0045893; GO:0045943; GO:0045944; GO:0045945; GO:0090535; GO:0090536; GO:0110016; GO:0140658; GO:0140751; GO:1905213; GO:1990830; GO:2001020 36423 XM_029347283.2 7 5 28 22 20 NA NA NA NA NA NA 36424 XM_029358430.2 95 90 17 64 16 NA NA NA NA NA NA 36425 XM_044327902.1 116 48 80 85 38 P0CT40 3.16e-79 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 36426 XM_044327943.1 36 0 58 32 1 NA NA NA NA NA NA 36427 XM_044311779.1 0 46 12 1 8 Q810D6 4.19e-36 Glutamate-rich WD repeat-containing protein 1 (Protein A301) Mus musculus (Mouse) DNA replication [GO:0006260]; nucleosome assembly [GO:0006334]; nucleosome disassembly [GO:0006337]; ribosome biogenesis [GO:0042254] GO:0003682; GO:0003688; GO:0005634; GO:0005654; GO:0005694; GO:0005730; GO:0005829; GO:0006260; GO:0006334; GO:0006337; GO:0032991; GO:0042254; GO:0042393 36428 XM_044311779.1 0 46 12 1 8 Q810D6 4.19e-36 Glutamate-rich WD repeat-containing protein 1 (Protein A301) Mus musculus (Mouse) DNA replication [GO:0006260]; nucleosome assembly [GO:0006334]; nucleosome disassembly [GO:0006337]; ribosome biogenesis [GO:0042254] GO:0003682; GO:0003688; GO:0005634; GO:0005654; GO:0005694; GO:0005730; GO:0005829; GO:0006260; GO:0006334; GO:0006337; GO:0032991; GO:0042254; GO:0042393 36429 XM_044323147.1 80 151 103 187 74 Q7RTR2 1.52e-78 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 36430 XM_044323147.1 80 151 103 187 74 Q7RTR2 1.74e-51 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 36431 XM_044323147.1 80 151 103 187 74 Q7RTR2 2.34e-49 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 36432 XM_029330578.2 18 0 72 0 0 NA NA NA NA NA NA 36433 XR_006391902.1 20 503 8 3 17 NA NA NA NA NA NA 36434 XR_003823821.2 41 22 69 115 233 NA NA NA NA NA NA 36435 XM_029349960.2 345 210 358 388 414 NA NA NA NA NA NA 36436 XM_044328497.1 0 166 1 0 0 Q9BYK8 7.55e-168 Helicase with zinc finger domain 2 (ATP-dependent helicase PRIC285) (Helicase with zinc finger 2, transcriptional coactivator) (PPAR-alpha-interacting complex protein 285) (PPAR-gamma DNA-binding domain-interacting protein 1) (PDIP1) (PPAR-gamma DBD-interacting protein 1) (Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein) (EC 3.6.4.-) Homo sapiens (Human) nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000184; GO:0003677; GO:0003723; GO:0003724; GO:0004540; GO:0005524; GO:0005654; GO:0005737; GO:0016020; GO:0030374; GO:0045944; GO:0046872 36437 XM_044328497.1 0 166 1 0 0 Q9BYK8 4.36e-103 Helicase with zinc finger domain 2 (ATP-dependent helicase PRIC285) (Helicase with zinc finger 2, transcriptional coactivator) (PPAR-alpha-interacting complex protein 285) (PPAR-gamma DNA-binding domain-interacting protein 1) (PDIP1) (PPAR-gamma DBD-interacting protein 1) (Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein) (EC 3.6.4.-) Homo sapiens (Human) nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000184; GO:0003677; GO:0003723; GO:0003724; GO:0004540; GO:0005524; GO:0005654; GO:0005737; GO:0016020; GO:0030374; GO:0045944; GO:0046872 36438 XM_044328497.1 0 166 1 0 0 Q9BYK8 7.86e-27 Helicase with zinc finger domain 2 (ATP-dependent helicase PRIC285) (Helicase with zinc finger 2, transcriptional coactivator) (PPAR-alpha-interacting complex protein 285) (PPAR-gamma DNA-binding domain-interacting protein 1) (PDIP1) (PPAR-gamma DBD-interacting protein 1) (Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein) (EC 3.6.4.-) Homo sapiens (Human) nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000184; GO:0003677; GO:0003723; GO:0003724; GO:0004540; GO:0005524; GO:0005654; GO:0005737; GO:0016020; GO:0030374; GO:0045944; GO:0046872 36439 XM_044307579.1 2317 5543 2527 3338 2312 Q8BN59 3.71e-36 La-related protein 6 (Acheron) (Achn) (La ribonucleoprotein domain family member 6) Mus musculus (Mouse) positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of mRNA binding [GO:1902416]; positive regulation of translation [GO:0045727]; RNA processing [GO:0006396] GO:0003723; GO:0003729; GO:0005634; GO:0005737; GO:0005844; GO:0006396; GO:0017022; GO:0032967; GO:0035613; GO:0045727; GO:0048027; GO:1902416; GO:1990825; GO:1990904 36440 XM_044315986.1 318 0 31 32 119 A3KN83 0 Protein strawberry notch homolog 1 (Monocyte protein 3) (MOP-3) Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355]; regulation of response to stimulus [GO:0048583] GO:0005634; GO:0006355; GO:0031490; GO:0042393; GO:0048583 36441 XM_044317837.1 0 4 144 95 165 NA NA NA NA NA NA 36442 XR_006393710.1 24 15 43 49 223 NA NA NA NA NA NA 36443 XR_006396316.1 2 10 0 8 33 NA NA NA NA NA NA 36444 XM_044327434.1 42 24 0 24 59 Q9QYP1 0 Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7) Rattus norvegicus (Rat) amyloid-beta clearance by cellular catabolic process [GO:0150094]; anatomical structure development [GO:0048856]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; proximal/distal pattern formation [GO:0009954]; receptor clustering [GO:0043113]; regulation of protein phosphorylation [GO:0001932]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001932; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0008104; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030326; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0043113; GO:0044853; GO:0048699; GO:0048813; GO:0048856; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 36445 XM_044327434.1 42 24 0 24 59 Q9QYP1 0 Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7) Rattus norvegicus (Rat) amyloid-beta clearance by cellular catabolic process [GO:0150094]; anatomical structure development [GO:0048856]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; proximal/distal pattern formation [GO:0009954]; receptor clustering [GO:0043113]; regulation of protein phosphorylation [GO:0001932]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001932; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0008104; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030326; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0043113; GO:0044853; GO:0048699; GO:0048813; GO:0048856; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 36446 XM_044327434.1 42 24 0 24 59 Q9QYP1 5.47e-137 Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7) Rattus norvegicus (Rat) amyloid-beta clearance by cellular catabolic process [GO:0150094]; anatomical structure development [GO:0048856]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; proximal/distal pattern formation [GO:0009954]; receptor clustering [GO:0043113]; regulation of protein phosphorylation [GO:0001932]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001932; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0008104; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030326; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0043113; GO:0044853; GO:0048699; GO:0048813; GO:0048856; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 36447 XM_029345370.2 5 3 21 15 2 Q6DFJ9 6.77e-55 Cyclin-J Xenopus laevis (African clawed frog) NA NA 36448 XM_044307831.1 119 111 63 134 173 Q9QYV8 0 DNA polymerase subunit gamma-1 (EC 2.7.7.7) (Mitochondrial DNA polymerase catalytic subunit) (PolG-alpha) Rattus norvegicus (Rat) aging [GO:0007568]; base-excision repair, gap-filling [GO:0006287]; cellular response to glucose stimulus [GO:0071333]; DNA-templated DNA replication [GO:0006261]; mitochondrial DNA replication [GO:0006264]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to light stimulus [GO:0009416] GO:0002020; GO:0003677; GO:0003682; GO:0003887; GO:0004527; GO:0005615; GO:0005730; GO:0005739; GO:0005759; GO:0005760; GO:0006261; GO:0006264; GO:0006287; GO:0007568; GO:0008408; GO:0009416; GO:0010332; GO:0032991; GO:0042645; GO:0043195; GO:0055093; GO:0071333; GO:0090305 36449 XM_029333177.2 7 0 10 0 6 P0C6B8 1.14e-49 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 36450 XM_029333177.2 7 0 10 0 6 P0C6B8 5.2e-46 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 36451 XM_029333177.2 7 0 10 0 6 P0C6B8 1.21e-36 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 36452 XM_029333177.2 7 0 10 0 6 P0C6B8 2.64e-36 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 36453 XM_044324502.1 23 0 0 31 0 NA NA NA NA NA NA 36454 XM_029349315.2 385 651 583 1439 1422 Q15075 3.23e-50 Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2) Homo sapiens (Human) chemical synaptic transmission, postsynaptic [GO:0099565]; early endosome to late endosome transport [GO:0045022]; endocytosis [GO:0006897]; modulation by host of viral process [GO:0044788]; synaptic vesicle to endosome fusion [GO:0016189]; vesicle fusion [GO:0006906] GO:0005516; GO:0005545; GO:0005737; GO:0005769; GO:0005829; GO:0005969; GO:0006897; GO:0006906; GO:0008270; GO:0016020; GO:0016189; GO:0019897; GO:0030742; GO:0031901; GO:0042803; GO:0044308; GO:0044788; GO:0045022; GO:0070062; GO:0098685; GO:0098794; GO:0098978; GO:0099565 36455 XM_029338231.2 1659 1010 1399 2268 1221 P51788 0 Chloride channel protein 2 (ClC-2) Homo sapiens (Human) acinar cell differentiation [GO:0090425]; cell differentiation involved in salivary gland development [GO:0060689]; chloride transport [GO:0006821]; lung development [GO:0030324]; regulation of aldosterone biosynthetic process [GO:0032347]; regulation of ion transmembrane transport [GO:0034765]; retina development in camera-type eye [GO:0060041] GO:0005247; GO:0005886; GO:0006821; GO:0030324; GO:0030425; GO:0032347; GO:0034707; GO:0034765; GO:0043204; GO:0060041; GO:0060689; GO:0090425 36456 XM_029349884.2 1282 904 680 1071 1398 A7SMR1 0 Eukaryotic translation initiation factor 3 subunit D (eIF3d) (Eukaryotic translation initiation factor 3 subunit 7) Nematostella vectensis (Starlet sea anemone) cap-dependent translational initiation [GO:0002191]; formation of cytoplasmic translation initiation complex [GO:0001732]; translational initiation [GO:0006413] GO:0001732; GO:0002191; GO:0003743; GO:0005852; GO:0006413; GO:0016282; GO:0033290; GO:0098808 36457 XM_044309064.1 18 15 24 104 68 Q3UQ28 1.83e-30 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 36458 XM_044309064.1 18 15 24 104 68 Q3UQ28 1.1e-25 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 36459 XM_044309117.1 8 0 0 3 8 NA NA NA NA NA NA 36460 XM_044328600.1 1173 1718 672 1455 1532 P08478 2.64e-137 Peptidyl-glycine alpha-amidating monooxygenase A (PAM-A) (Peptide C-terminal alpha-amidating enzyme I) (AE-I) (Peptidyl-glycine alpha-amidating monooxygenase I) [Includes: Peptidylglycine alpha-hydroxylating monooxygenase A (PHM-A) (EC 1.14.17.3); Peptidyl-alpha-hydroxyglycine alpha-amidating lyase A (EC 4.3.2.5) (Peptidylamidoglycolate lyase-A) (PAL-A)] Xenopus laevis (African clawed frog) peptide metabolic process [GO:0006518] GO:0004504; GO:0004598; GO:0005507; GO:0006518; GO:0030658 36461 XM_029350386.2 5515 4023 4401 7591 5108 P83205 4.47e-118 Cathepsin B (EC 3.4.22.1) (Cathepsin B1) [Cleaved into: Cathepsin B light chain; Cathepsin B heavy chain] Ovis aries (Sheep) cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; decidualization [GO:0046697]; epithelial cell differentiation [GO:0030855]; negative regulation of peptidase activity [GO:0010466]; proteolysis involved in protein catabolic process [GO:0051603]; thyroid hormone generation [GO:0006590]; viral entry into host cell [GO:0046718] GO:0004175; GO:0004197; GO:0005518; GO:0005615; GO:0005764; GO:0006590; GO:0009897; GO:0010466; GO:0016324; GO:0030574; GO:0030855; GO:0042470; GO:0043394; GO:0046697; GO:0046718; GO:0048471; GO:0051603; GO:0097067; GO:1904090 36462 XM_029351552.2 0 0 668 0 324 Q75N73 8.67e-62 Metal cation symporter ZIP14 (Factor for adipocyte differentiation 123) (FAD-123) (Solute carrier family 39 member 14) (Zrt- and Irt-like protein 14) (ZIP-14) Mus musculus (Mouse) cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; cellular zinc ion homeostasis [GO:0006882]; chondrocyte differentiation [GO:0002062]; gluconeogenesis [GO:0006094]; import across plasma membrane [GO:0098739]; inorganic cation transmembrane transport [GO:0098662]; insulin receptor signaling pathway [GO:0008286]; iron import into cell [GO:0033212]; iron ion transmembrane transport [GO:0034755]; iron ion transport [GO:0006826]; manganese ion homeostasis [GO:0055071]; manganese ion transmembrane transport [GO:0071421]; negative regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051344]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; regulation of hormone levels [GO:0010817]; zinc ion import across plasma membrane [GO:0071578]; zinc ion transmembrane transport [GO:0071577]; zinc ion transport [GO:0006829] GO:0002062; GO:0005381; GO:0005384; GO:0005385; GO:0005765; GO:0005886; GO:0006094; GO:0006826; GO:0006829; GO:0006882; GO:0008286; GO:0010817; GO:0015086; GO:0015093; GO:0015296; GO:0016020; GO:0016323; GO:0016324; GO:0031901; GO:0031902; GO:0032869; GO:0033212; GO:0034755; GO:0045745; GO:0051344; GO:0055071; GO:0071333; GO:0071421; GO:0071577; GO:0071578; GO:0098662; GO:0098739 36463 XM_044327904.1 0 3 3 0 57 NA NA NA NA NA NA 36464 XM_044309645.1 373 223 185 195 227 Q9Z2W0 0 Aspartyl aminopeptidase (EC 3.4.11.21) Mus musculus (Mouse) proteolysis [GO:0006508] GO:0004177; GO:0005829; GO:0006508; GO:0008237; GO:0008270; GO:0042802 36465 XM_044327244.1 37 15 51 24 149 P08953 5.15e-61 Protein toll Drosophila melanogaster (Fruit fly) antifungal innate immune response [GO:0061760]; cell adhesion [GO:0007155]; cell competition in a multicellular organism [GO:0035212]; defense response to Gram-positive bacterium [GO:0050830]; defense response to oomycetes [GO:0002229]; detection of virus [GO:0009597]; dorsal/ventral axis specification [GO:0009950]; heart development [GO:0007507]; innate immune response [GO:0045087]; larval somatic muscle development [GO:0007526]; negative regulation of cell growth [GO:0030308]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of multicellular organism growth [GO:0040015]; positive regulation of antifungal peptide production [GO:0002804]; positive regulation of antimicrobial peptide production [GO:0002225]; positive regulation of hemocyte proliferation [GO:0035208]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of embryonic pattern specification [GO:1902875]; response to tumor cell [GO:0002347]; response to wounding [GO:0009611]; synapse assembly [GO:0007416]; synaptic target inhibition [GO:0016201]; Toll signaling pathway [GO:0008063]; toll-like receptor signaling pathway [GO:0002224] GO:0002224; GO:0002225; GO:0002229; GO:0002347; GO:0002804; GO:0004888; GO:0004896; GO:0005769; GO:0005886; GO:0007155; GO:0007416; GO:0007507; GO:0007526; GO:0008063; GO:0009597; GO:0009611; GO:0009897; GO:0009950; GO:0009986; GO:0016201; GO:0019955; GO:0030308; GO:0032154; GO:0035208; GO:0035212; GO:0038023; GO:0040015; GO:0042802; GO:0045087; GO:0045944; GO:0046627; GO:0046790; GO:0050135; GO:0050830; GO:0061760; GO:0061809; GO:0070976; GO:1902875 36466 XM_044325213.1 2 0 14 11 0 NA NA NA NA NA NA 36467 XR_006396375.1 155 31 29 46 121 NA NA NA NA NA NA 36468 XM_029324516.2 1995 2253 1609 1770 1708 Q4V8V1 7.53e-86 Breast cancer metastasis-suppressor 1-like protein-A Danio rerio (Zebrafish) (Brachydanio rerio) histone deacetylation [GO:0016575]; negative regulation of cell migration [GO:0030336]; negative regulation of stem cell population maintenance [GO:1902455]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; positive regulation of stem cell population maintenance [GO:1902459] GO:0000122; GO:0016575; GO:0030336; GO:0030512; GO:0042826; GO:0070822; GO:1902455; GO:1902459 36469 XR_006394631.1 94 14 6 14 77 Q80UY1 2.32e-107 Carnosine N-methyltransferase (EC 2.1.1.22) Mus musculus (Mouse) carnosine metabolic process [GO:0035498]; methylation [GO:0032259] GO:0005634; GO:0005829; GO:0008757; GO:0030735; GO:0032259; GO:0035498; GO:0042803 36470 XR_006392783.1 6 133 9 214 134 NA NA NA NA NA NA 36471 XM_029332998.2 634 336 135 392 347 P36871 0 Phosphoglucomutase-1 (PGM 1) (EC 5.4.2.2) (Glucose phosphomutase 1) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; gluconeogenesis [GO:0006094]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096] GO:0000287; GO:0004614; GO:0005576; GO:0005737; GO:0005829; GO:0005975; GO:0006006; GO:0006094; GO:0006096; GO:0070062; GO:1904724; GO:1904813 36472 XM_029351440.2 498 530 461 373 298 NA NA NA NA NA NA 36473 XR_006398032.1 0 9 0 0 0 NA NA NA NA NA NA 36474 XM_029337576.2 522 480 524 681 875 Q64732 1.43e-55 Forkhead box protein B1 (Transcription factor FKH-5) Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; axon target recognition [GO:0007412]; cell differentiation [GO:0030154]; cell migration in diencephalon [GO:0061381]; epithelial cell differentiation involved in mammary gland alveolus development [GO:0061030]; floor plate development [GO:0033504]; hypothalamus cell migration [GO:0021855]; inferior colliculus development [GO:0061379]; lactation [GO:0007595]; mammary gland lobule development [GO:0061377]; mammillary body development [GO:0021767]; mammillothalamic axonal tract development [GO:0061374]; midbrain development [GO:0030901]; negative regulation of neuron apoptotic process [GO:0043524]; regulation of transcription by RNA polymerase II [GO:0006357]; somitogenesis [GO:0001756]; spinal cord development [GO:0021510]; telencephalon cell migration [GO:0022029]; thalamus development [GO:0021794]; urogenital system development [GO:0001655]; visual learning [GO:0008542] GO:0000978; GO:0000981; GO:0001655; GO:0001756; GO:0005634; GO:0006357; GO:0007412; GO:0007595; GO:0008542; GO:0009653; GO:0021510; GO:0021767; GO:0021794; GO:0021855; GO:0022029; GO:0030154; GO:0030901; GO:0033504; GO:0043524; GO:0043565; GO:0061030; GO:0061374; GO:0061377; GO:0061379; GO:0061381; GO:1990837 36475 XM_029339266.2 48 4 23 0 0 Q9N2B7 3.31e-39 5-hydroxytryptamine receptor 1B (5-HT-1B) (5-HT1B) (Serotonin receptor 1B) Gorilla gorilla gorilla (Western lowland gorilla) adenylate cyclase-inhibiting serotonin receptor signaling pathway [GO:0007198]; behavior [GO:0007610]; bone remodeling [GO:0046849]; cellular response to alkaloid [GO:0071312]; cellular response to xenobiotic stimulus [GO:0071466]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; negative regulation of serotonin secretion [GO:0014063]; regulation of behavior [GO:0050795]; vasoconstriction [GO:0042310] GO:0004993; GO:0005886; GO:0007187; GO:0007198; GO:0007268; GO:0007610; GO:0014063; GO:0030425; GO:0030594; GO:0042310; GO:0045202; GO:0046849; GO:0050795; GO:0051378; GO:0071312; GO:0071466 36476 XM_044324352.1 16 3 29 15 277 NA NA NA NA NA NA 36477 XR_006394511.1 79 12 30 91 231 NA NA NA NA NA NA 36478 XM_029334024.2 569 567 317 430 150 Q9VFB2 2.81e-35 28S ribosomal protein S10, mitochondrial (MRP-S10) (S10mt) Drosophila melanogaster (Fruit fly) mitochondrial translation [GO:0032543] GO:0003735; GO:0005739; GO:0005763; GO:0032543 36479 XM_044307375.1 256 174 195 271 113 NA NA NA NA NA NA 36480 XM_029323777.2 1197 864 730 1404 1439 Q9P2J5 0 Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS) Homo sapiens (Human) cellular response to amino acid starvation [GO:0034198]; cellular response to amino acid stimulus [GO:0071230]; cellular response to leucine [GO:0071233]; cellular response to leucine starvation [GO:1990253]; glutaminyl-tRNA aminoacylation [GO:0006425]; leucyl-tRNA aminoacylation [GO:0006429]; positive regulation of GTPase activity [GO:0043547]; positive regulation of TOR signaling [GO:0032008]; positive regulation of TORC1 signaling [GO:1904263]; regulation of cell size [GO:0008361]; tRNA aminoacylation for protein translation [GO:0006418] GO:0002161; GO:0004819; GO:0004823; GO:0005096; GO:0005524; GO:0005737; GO:0005764; GO:0005783; GO:0005829; GO:0006418; GO:0006425; GO:0006429; GO:0008361; GO:0012505; GO:0016604; GO:0017101; GO:0032008; GO:0034198; GO:0043547; GO:0071230; GO:0071233; GO:1904263; GO:1990253 36481 XM_029338415.2 402 515 179 592 1093 Q8BZI6 2.28e-45 Protein GUCD1 (Guanylyl cyclase domain-containing protein 1) (Protein LLN4) Mus musculus (Mouse) NA NA 36482 XM_044312358.1 0 17 0 0 0 NA NA NA NA NA NA 36483 XR_003823042.2 57 96 83 425 297 NA NA NA NA NA NA 36484 XM_044321569.1 1188 1598 295 1122 469 NA NA NA NA NA NA 36485 XM_029340577.2 1346 1223 834 1138 979 NA NA NA NA NA NA 36486 XM_044327818.1 671 326 113 412 641 NA NA NA NA NA NA 36487 XM_044314076.1 2 4 1 0 27 NA NA NA NA NA NA 36488 XR_003825411.2 11 6 9 4 5 NA NA NA NA NA NA 36489 XR_006397473.1 428 1190 1965 250 179 NA NA NA NA NA NA 36490 XM_044317790.1 0 0 0 0 13 Q5ZLA6 0 Unconventional myosin-Ic (Myosin I beta) (MMI-beta) (MMIb) Gallus gallus (Chicken) actin filament organization [GO:0007015]; vesicle transport along actin filament [GO:0030050] GO:0000146; GO:0005524; GO:0005737; GO:0005886; GO:0005902; GO:0005938; GO:0007015; GO:0015629; GO:0016459; GO:0030050; GO:0031410; GO:0031982; GO:0032587; GO:0051015; GO:0060171 36491 XM_044318814.1 13 6 0 42 24 NA NA NA NA NA NA 36492 XM_029346418.2 127 23 12 50 33 Q16822 0 Phosphoenolpyruvate carboxykinase [GTP], mitochondrial (PEPCK-M) (EC 4.1.1.32) Homo sapiens (Human) cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glycerol biosynthetic process from pyruvate [GO:0046327]; hepatocyte differentiation [GO:0070365]; NADH oxidation [GO:0006116]; oxaloacetate metabolic process [GO:0006107]; positive regulation of insulin secretion [GO:0032024]; propionate catabolic process [GO:0019543]; response to lipid [GO:0033993]; response to lipopolysaccharide [GO:0032496]; response to starvation [GO:0042594] GO:0004611; GO:0004613; GO:0005525; GO:0005739; GO:0005759; GO:0005829; GO:0006094; GO:0006107; GO:0006116; GO:0019543; GO:0030145; GO:0032024; GO:0032496; GO:0032869; GO:0033993; GO:0042594; GO:0046327; GO:0070365; GO:0071333; GO:0071356; GO:0071549 36493 XM_044328001.1 3 10 0 2166 8 NA NA NA NA NA NA 36494 XM_029334455.2 11547 9665 8284 13187 11223 Q26636 3.83e-128 Cathepsin L (EC 3.4.22.15) [Cleaved into: Cathepsin L heavy chain; Cathepsin L light chain] Sarcophaga peregrina (Flesh fly) (Boettcherisca peregrina) cell differentiation [GO:0030154]; proteolysis [GO:0006508] GO:0004197; GO:0005764; GO:0006508; GO:0030154 36495 XM_044328512.1 0 90 6 3 3 NA NA NA NA NA NA 36496 XR_006396627.1 17 0 27 0 58 NA NA NA NA NA NA 36497 XR_006391314.1 80 33 20 15 31 NA NA NA NA NA NA 36498 XM_029356440.2 372 226 252 285 818 Q9U3S9 7.24e-36 Zinc metalloproteinase nas-6 (EC 3.4.24.-) (Nematode astacin 6) Caenorhabditis elegans pharyngeal pumping [GO:0043050]; pharynx development [GO:0060465]; proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0006508; GO:0008270; GO:0043050; GO:0060465 36499 XM_029350826.2 582 304 297 501 193 Q5MPA9 3.9e-171 Serine/threonine-protein kinase DCLK2 (EC 2.7.11.1) (CaMK-like CREB regulatory kinase 2) (CL2) (CLICK-II) (CLICK2) (Doublecortin-like and CAM kinase-like 2) (Doublecortin-like kinase 2) Rattus norvegicus (Rat) hippocampus development [GO:0021766]; intracellular signal transduction [GO:0035556]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of protein localization to nucleus [GO:1900181]; peptidyl-serine phosphorylation [GO:0018105]; protein localization to nucleus [GO:0034504]; pyramidal neuron development [GO:0021860] GO:0000226; GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0005856; GO:0008017; GO:0018105; GO:0021766; GO:0021860; GO:0034504; GO:0035556; GO:0106310; GO:1900181 36500 XM_029339311.2 544 494 147 219 115 NA NA NA NA NA NA 36501 XM_044325533.1 7 0 0 2 0 B1AS29 8.62e-83 Glutamate receptor ionotropic, kainate 3 (GluK3) (Glutamate receptor 7) (GluR-7) (GluR7) Mus musculus (Mouse) G protein-coupled glutamate receptor signaling pathway [GO:0007216]; glutamate receptor signaling pathway [GO:0007215]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; regulation of membrane potential [GO:0042391]; synaptic transmission, glutamatergic [GO:0035249] GO:0001640; GO:0004970; GO:0005886; GO:0007215; GO:0007216; GO:0008066; GO:0015276; GO:0015277; GO:0030424; GO:0030425; GO:0032839; GO:0032983; GO:0035249; GO:0038023; GO:0042391; GO:0042734; GO:0043195; GO:0043204; GO:0045211; GO:0050804; GO:0051967; GO:0098978; GO:0099507; GO:1904315 36502 XM_029339395.2 7960 11618 5455 8050 6735 G1SWI6 2.43e-79 NA NA NA NA 36503 XM_029333858.2 2067 1332 804 1590 1873 E9PY46 0 Intraflagellar transport protein 140 homolog (WD and tetratricopeptide repeats protein 2) Mus musculus (Mouse) cilium assembly [GO:0060271]; determination of left/right symmetry [GO:0007368]; embryonic brain development [GO:1990403]; embryonic camera-type eye development [GO:0031076]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digit morphogenesis [GO:0042733]; heart development [GO:0007507]; intraciliary retrograde transport [GO:0035721]; intraciliary transport [GO:0042073]; limb morphogenesis [GO:0035108]; neural tube patterning [GO:0021532]; non-motile cilium assembly [GO:1905515]; photoreceptor cell outer segment organization [GO:0035845]; protein localization to cilium [GO:0061512]; regulation of cilium assembly [GO:1902017]; regulation of smoothened signaling pathway [GO:0008589] GO:0005813; GO:0005814; GO:0005929; GO:0005930; GO:0007368; GO:0007507; GO:0008589; GO:0021532; GO:0030991; GO:0031076; GO:0032391; GO:0035108; GO:0035721; GO:0035845; GO:0036064; GO:0042073; GO:0042733; GO:0048701; GO:0060271; GO:0061512; GO:0097730; GO:0120199; GO:1902017; GO:1905515; GO:1990403 36504 XM_029326482.2 24 8 30 6 31 NA NA NA NA NA NA 36505 XM_044316315.1 233 386 116 106 62 P16157 2.41e-89 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 36506 XM_044316315.1 233 386 116 106 62 P16157 2.59e-81 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 36507 XM_044316315.1 233 386 116 106 62 P16157 2.43e-71 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 36508 XM_044316315.1 233 386 116 106 62 P16157 1.44e-70 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 36509 XM_044316315.1 233 386 116 106 62 P16157 2.83e-66 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 36510 XM_044316315.1 233 386 116 106 62 P16157 2.02e-62 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 36511 XM_044316315.1 233 386 116 106 62 P16157 1.71e-37 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 36512 XM_029345929.2 1037 615 477 794 1207 NA NA NA NA NA NA 36513 XM_044310228.1 48 52 7 43 107 Q96DM1 8.11e-41 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 36514 XM_029337640.2 243 162 107 138 197 Q8AWF4 3.28e-24 Kinetochore protein Nuf2-A (xNuf2) (Cell division cycle-associated protein 1-A) Xenopus laevis (African clawed frog) cell cycle [GO:0007049]; cell division [GO:0051301] GO:0005634; GO:0007049; GO:0031262; GO:0051301 36515 XM_029337336.2 786 1144 489 884 443 O42115 2.03e-28 Aristaless-related homeobox protein (ARX) Danio rerio (Zebrafish) (Brachydanio rerio) enteric nervous system development [GO:0048484]; neuron development [GO:0048666]; pancreatic A cell development [GO:0003322]; regulation of transcription by RNA polymerase II [GO:0006357]; subthalamus development [GO:0021539]; telencephalon development [GO:0021537]; thalamus development [GO:0021794] GO:0000977; GO:0000981; GO:0003322; GO:0005634; GO:0006357; GO:0021537; GO:0021539; GO:0021794; GO:0048484; GO:0048666 36516 XR_006392759.1 308 246 153 188 86 Q868M7 3.05e-125 Galactose/N-acetylgalactosamine-binding lectin CEL-III (Gal/GalNAc-binding lectin CEL-III) (CEL-III) (Hemolytic lectin CEL-III) (Lectin CEL-III) Cucumaria echinata (Sea cucumber) antibacterial humoral response [GO:0019731]; cell killing [GO:0001906]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; disruption of membrane integrity in another organism [GO:0051673]; hemolysis in another organism [GO:0044179]; positive regulation of erythrocyte aggregation [GO:0034120]; protein homooligomerization [GO:0051260] GO:0000287; GO:0001906; GO:0005509; GO:0005534; GO:0005615; GO:0019731; GO:0030395; GO:0034120; GO:0042806; GO:0043621; GO:0044179; GO:0046871; GO:0050829; GO:0050830; GO:0051260; GO:0051673; GO:1903777 36517 XR_006392759.1 308 246 153 188 86 Q868M7 3.05e-125 Galactose/N-acetylgalactosamine-binding lectin CEL-III (Gal/GalNAc-binding lectin CEL-III) (CEL-III) (Hemolytic lectin CEL-III) (Lectin CEL-III) Cucumaria echinata (Sea cucumber) antibacterial humoral response [GO:0019731]; cell killing [GO:0001906]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; disruption of membrane integrity in another organism [GO:0051673]; hemolysis in another organism [GO:0044179]; positive regulation of erythrocyte aggregation [GO:0034120]; protein homooligomerization [GO:0051260] GO:0000287; GO:0001906; GO:0005509; GO:0005534; GO:0005615; GO:0019731; GO:0030395; GO:0034120; GO:0042806; GO:0043621; GO:0044179; GO:0046871; GO:0050829; GO:0050830; GO:0051260; GO:0051673; GO:1903777 36518 XM_044317499.1 17 189 69 291 72 NA NA NA NA NA NA 36519 XM_029348311.2 175 104 40 197 141 NA NA NA NA NA NA 36520 XM_044327001.1 142 74 44 66 133 NA NA NA NA NA NA 36521 XM_029347154.2 3439 1808 1241 2529 1830 O88427 0 Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage-gated calcium channel subunit alpha Cav3.2) Mus musculus (Mouse) aldosterone biosynthetic process [GO:0032342]; calcium ion import [GO:0070509]; calcium ion transport [GO:0006816]; cortisol biosynthetic process [GO:0034651]; inorganic cation transmembrane transport [GO:0098662]; membrane depolarization during action potential [GO:0086010]; neuronal action potential [GO:0019228]; positive regulation of acrosome reaction [GO:2000344]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of cardiac muscle cell contraction [GO:0106134]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; sensory perception of pain [GO:0019233] GO:0001518; GO:0005244; GO:0005248; GO:0005634; GO:0005737; GO:0005886; GO:0005891; GO:0005901; GO:0006816; GO:0008332; GO:0016020; GO:0019228; GO:0019233; GO:0030425; GO:0032342; GO:0034651; GO:0034765; GO:0042383; GO:0042391; GO:0043005; GO:0043204; GO:0045211; GO:0045956; GO:0046872; GO:0048787; GO:0070509; GO:0086010; GO:0097110; GO:0098662; GO:0098978; GO:0106134; GO:2000344 36522 XM_029347154.2 3439 1808 1241 2529 1830 O88427 2.4e-88 Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage-gated calcium channel subunit alpha Cav3.2) Mus musculus (Mouse) aldosterone biosynthetic process [GO:0032342]; calcium ion import [GO:0070509]; calcium ion transport [GO:0006816]; cortisol biosynthetic process [GO:0034651]; inorganic cation transmembrane transport [GO:0098662]; membrane depolarization during action potential [GO:0086010]; neuronal action potential [GO:0019228]; positive regulation of acrosome reaction [GO:2000344]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of cardiac muscle cell contraction [GO:0106134]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; sensory perception of pain [GO:0019233] GO:0001518; GO:0005244; GO:0005248; GO:0005634; GO:0005737; GO:0005886; GO:0005891; GO:0005901; GO:0006816; GO:0008332; GO:0016020; GO:0019228; GO:0019233; GO:0030425; GO:0032342; GO:0034651; GO:0034765; GO:0042383; GO:0042391; GO:0043005; GO:0043204; GO:0045211; GO:0045956; GO:0046872; GO:0048787; GO:0070509; GO:0086010; GO:0097110; GO:0098662; GO:0098978; GO:0106134; GO:2000344 36523 XM_044312751.1 18 0 36 20 0 Q17RS7 2.33e-68 Flap endonuclease GEN homolog 1 (EC 3.1.-.-) Homo sapiens (Human) double-strand break repair via homologous recombination [GO:0000724]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; regulation of centrosome duplication [GO:0010824]; replication fork processing [GO:0031297]; resolution of mitotic recombination intermediates [GO:0071140]; resolution of recombination intermediates [GO:0071139] GO:0000287; GO:0000400; GO:0000724; GO:0005654; GO:0005813; GO:0008821; GO:0010824; GO:0017108; GO:0031297; GO:0042803; GO:0071139; GO:0071140; GO:0090267 36524 XM_029356012.2 88 72 31 74 105 A2AJ77 9.52e-110 PR domain zinc finger protein 12 (EC 2.1.1.-) (PR domain-containing protein 12) Mus musculus (Mouse) detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; neuron projection development [GO:0031175]; positive regulation of histone H3-K9 dimethylation [GO:1900111]; protein methylation [GO:0006479]; regulation of gene expression [GO:0010468]; sensory perception of pain [GO:0019233] GO:0000122; GO:0003677; GO:0005634; GO:0005654; GO:0006479; GO:0008168; GO:0010468; GO:0019233; GO:0022008; GO:0031175; GO:0046872; GO:0050965; GO:0140713; GO:1900111; GO:1990226 36525 XM_044308430.1 26 64 38 64 43 NA NA NA NA NA NA 36526 XM_044317518.1 25 23 2 34 37 NA NA NA NA NA NA 36527 XM_044315106.1 0 0 0 14 0 NA NA NA NA NA NA 36528 XM_029327992.2 268 210 158 219 320 Q8VDI9 0 Alpha-1,2-mannosyltransferase ALG9 (EC 2.4.1.259) (EC 2.4.1.261) (Dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase) (Dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase) Mus musculus (Mouse) protein N-linked glycosylation [GO:0006487] GO:0000026; GO:0000030; GO:0005789; GO:0006487; GO:0052918; GO:0052926 36529 XM_044326851.1 2 0 2 0 931 NA NA NA NA NA NA 36530 XM_029346798.2 669 596 379 582 990 Q95K40 1.75e-34 Coiled-coil domain-containing protein 83 Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA NA 36531 XM_029335466.2 376 21 276 399 269 Q8JZP9 3.96e-54 GAS2-like protein 1 (Growth arrest-specific protein 2-like 1) Mus musculus (Mouse) actin crosslink formation [GO:0051764]; cellular response to starvation [GO:0009267]; cellular response to thyroid hormone stimulus [GO:0097067]; microtubule bundle formation [GO:0001578]; negative regulation of cell growth [GO:0030308]; negative regulation of erythrocyte differentiation [GO:0045647]; negative regulation of gene expression [GO:0010629]; negative regulation of microtubule depolymerization [GO:0007026]; protein localization to microtubule plus-end [GO:1904825]; regulation of cell cycle [GO:0051726]; regulation of microtubule polymerization or depolymerization [GO:0031110] GO:0001578; GO:0001725; GO:0005737; GO:0005874; GO:0005884; GO:0007026; GO:0008017; GO:0008093; GO:0009267; GO:0010629; GO:0030308; GO:0031110; GO:0035371; GO:0045647; GO:0046966; GO:0051015; GO:0051726; GO:0051764; GO:0097067; GO:1904825 36532 XM_029338030.2 1375 994 441 1127 528 NA NA NA NA NA NA 36533 XM_044327688.1 53 0 0 2 0 NA NA NA NA NA NA 36534 XR_006395641.1 21 185 27 23 24 NA NA NA NA NA NA 36535 XM_044326892.1 2293 1227 1424 2490 2130 NA NA NA NA NA NA 36536 XR_006396861.1 91 91 176 463 89 NA NA NA NA NA NA 36537 XM_044314960.1 0 0 10 0 0 NA NA NA NA NA NA 36538 XM_044328378.1 238 0 0 401 38 Q99315 8.34e-76 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 36539 XM_029355072.2 416 271 320 358 242 Q801S4 2.15e-90 Uncharacterized protein KIAA0930 homolog Xenopus laevis (African clawed frog) NA NA 36540 XM_044325662.1 2503 1489 804 1579 1262 Q4R7W3 7.04e-136 Ras-specific guanine nucleotide-releasing factor RalGPS2 (Ral GEF with PH domain and SH3-binding motif 2) (RalA exchange factor RalGPS2) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) small GTPase mediated signal transduction [GO:0007264] GO:0005085; GO:0005737; GO:0005886; GO:0007264 36541 XR_003823896.2 714 431 626 454 121 NA NA NA NA NA NA 36542 XM_029348880.2 465 322 227 397 526 Q5F389 3.54e-149 WW domain-containing oxidoreductase (EC 1.1.1.-) Gallus gallus (Chicken) cellular response to transforming growth factor beta stimulus [GO:0071560]; extrinsic apoptotic signaling pathway [GO:0097191]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; negative regulation of Wnt signaling pathway [GO:0030178]; osteoblast differentiation [GO:0001649]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of transcription by RNA polymerase II [GO:0045944]; skeletal system morphogenesis [GO:0048705]; Wnt signaling pathway [GO:0016055] GO:0001649; GO:0003713; GO:0005654; GO:0005739; GO:0005794; GO:0005829; GO:0005886; GO:0005902; GO:0016055; GO:0016491; GO:0019899; GO:0030178; GO:0045944; GO:0048705; GO:0071560; GO:0072332; GO:0090575; GO:0097191; GO:2001241 36543 XM_029337311.2 233 0 0 0 0 F1R8P4 1.01e-51 Glycine receptor subunit alpha-2 Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0004888; GO:0005254; GO:0016594; GO:0016933; GO:0022824; GO:0034707; GO:0042995; GO:0045211; GO:0046872 36544 XM_029353957.2 143 194 135 436 432 Q9K7A0 2.63e-30 Probable cysteine desulfurase (EC 2.8.1.7) Halalkalibacterium halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) (Bacillus halodurans) cysteine metabolic process [GO:0006534] GO:0006534; GO:0030170; GO:0031071 36545 XM_029329834.2 215 115 133 125 185 NA NA NA NA NA NA 36546 XM_029338045.2 284 423 297 380 207 Q91WC1 3.63e-41 Protection of telomeres protein 1 (mPot1) (POT1-like telomere end-binding protein) Mus musculus (Mouse) chromosome organization [GO:0051276]; DNA duplex unwinding [GO:0032508]; establishment of protein localization to telomere [GO:0070200]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; positive regulation of DNA helicase activity [GO:1905776]; positive regulation of DNA strand elongation [GO:0060383]; positive regulation of helicase activity [GO:0051096]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere maintenance [GO:0032206]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of DNA helicase activity [GO:1905774]; regulation of double-strand break repair via nonhomologous end joining [GO:2001032]; regulation of telomere maintenance via telomerase [GO:0032210]; telomere assembly [GO:0032202]; telomere capping [GO:0016233]; telomere maintenance via telomerase [GO:0007004]; telomeric D-loop disassembly [GO:0061820] GO:0000781; GO:0000783; GO:0005654; GO:0007004; GO:0010521; GO:0016233; GO:0017151; GO:0032202; GO:0032206; GO:0032210; GO:0032211; GO:0032212; GO:0032508; GO:0042162; GO:0043047; GO:0051096; GO:0051276; GO:0051973; GO:0051974; GO:0060383; GO:0061820; GO:0061821; GO:0070187; GO:0070200; GO:0098505; GO:1905773; GO:1905774; GO:1905776; GO:1990955; GO:2001032 36547 XM_044327306.1 0 1 0 0 6 NA NA NA NA NA NA 36548 XM_029336003.2 628 312 254 535 460 Q8IWF2 0 FAD-dependent oxidoreductase domain-containing protein 2 (Endoplasmic reticulum flavoprotein associated with degradation) Homo sapiens (Human) ubiquitin-dependent ERAD pathway [GO:0030433] GO:0004497; GO:0005788; GO:0030433; GO:0050660 36549 XM_044316346.1 0 0 0 2 28 NA NA NA NA NA NA 36550 XM_029340124.2 42 164 65 488 304 Q9WUJ8 3.19e-38 Origin recognition complex subunit 6 Mus musculus (Mouse) DNA replication initiation [GO:0006270]; DNA-templated DNA replication [GO:0006261]; negative regulation of cell division [GO:0051782] GO:0000808; GO:0001650; GO:0003677; GO:0005654; GO:0005664; GO:0006261; GO:0006270; GO:0051782 36551 XM_044327976.1 80 0 134 138 0 NA NA NA NA NA NA 36552 XM_044314476.1 1062 553 974 6 1283 Q9NZJ4 0 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 36553 XM_044314476.1 1062 553 974 6 1283 Q9NZJ4 4.81e-42 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 36554 XM_044323846.1 134 44 45 12 93 C6FG12 1.08e-26 Protein NLRC5 Ictalurus punctatus (Channel catfish) (Silurus punctatus) innate immune response [GO:0045087] GO:0005524; GO:0005737; GO:0045087 36555 XM_044312977.1 43 315 10 40 60 NA NA NA NA NA NA 36556 XM_029327087.2 52 24 14 7 22 NA NA NA NA NA NA 36557 XM_044307188.1 61 114 63 39 49 NA NA NA NA NA NA 36558 XR_006398157.1 436 152 53 3 137 NA NA NA NA NA NA 36559 XM_029326696.2 665 512 485 469 587 O62852 3.46e-71 Short transient receptor potential channel 5 (Rtrp5) (TrpC5) (Capacitative calcium entry channel 2) (CCE2) Oryctolagus cuniculus (Rabbit) neuron apoptotic process [GO:0051402]; phosphatidylserine exposure on apoptotic cell surface [GO:0070782] GO:0005262; GO:0005886; GO:0034704; GO:0051402; GO:0070679; GO:0070782 36560 XM_029356972.2 3155 3918 1797 4202 2639 Q9QYI5 6.66e-36 DnaJ homolog subfamily B member 2 (DnaJ homolog subfamily B member 10) (mDj8) Mus musculus (Mouse) chaperone-mediated protein folding [GO:0061077]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of protein binding [GO:0032091]; negative regulation of protein deubiquitination [GO:0090086]; positive regulation of ATP-dependent activity [GO:0032781]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein refolding [GO:0042026]; regulation of chaperone-mediated protein folding [GO:1903644]; regulation of protein localization [GO:0032880]; regulation of protein ubiquitination [GO:0031396]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0000502; GO:0001671; GO:0005634; GO:0005737; GO:0005789; GO:0005829; GO:0008285; GO:0016234; GO:0030308; GO:0030433; GO:0030544; GO:0031396; GO:0031398; GO:0031593; GO:0031625; GO:0031965; GO:0032091; GO:0032436; GO:0032781; GO:0032880; GO:0042026; GO:0043130; GO:0043161; GO:0048471; GO:0051082; GO:0051087; GO:0061077; GO:0070628; GO:0090084; GO:0090086; GO:0140036; GO:1903644 36561 XM_029346492.2 543 242 504 204 987 Q9CS00 0 Splicing factor Cactin Mus musculus (Mouse) cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; innate immune response [GO:0045087]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339] GO:0000398; GO:0001933; GO:0005634; GO:0005654; GO:0005681; GO:0005737; GO:0005829; GO:0016607; GO:0031665; GO:0032088; GO:0032688; GO:0032717; GO:0032720; GO:0034122; GO:0043124; GO:0045087; GO:0045292; GO:0045824; GO:0060339; GO:0071013; GO:0071222; GO:0071347; GO:0071356 36562 XM_029340607.2 0 0 51 0 160 NA NA NA NA NA NA 36563 XM_029323722.2 0 0 47 0 0 E1BD52 2.9e-146 Transmembrane protein 245 Bos taurus (Bovine) NA GO:0016020 36564 XM_044307186.1 188 85 98 369 742 NA NA NA NA NA NA 36565 XM_044308777.1 289 235 614 592 1498 Q6XP49 5.14e-74 Zinc finger protein GLIS3 (GLI-similar 3) Mus musculus (Mouse) negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366] GO:0000122; GO:0000977; GO:0000978; GO:0000981; GO:0001227; GO:0001228; GO:0003677; GO:0003700; GO:0005634; GO:0006357; GO:0006366; GO:0045944; GO:0046872 36566 XM_044310989.1 0 46 17 0 26 Q3T108 2.79e-98 Proteasome subunit beta type-4 Bos taurus (Bovine) proteasomal protein catabolic process [GO:0010498] GO:0005634; GO:0005654; GO:0005739; GO:0005839; GO:0010498; GO:0019774; GO:0036064 36567 XM_029339920.2 120 127 60 241 45 P31422 0 Metabotropic glutamate receptor 3 (mGluR3) Rattus norvegicus (Rat) G protein-coupled glutamate receptor signaling pathway [GO:0007216]; gene expression [GO:0010467]; modulation of chemical synaptic transmission [GO:0050804]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; regulation of synaptic transmission, glutamatergic [GO:0051966]; sensory perception of pain [GO:0019233] GO:0001640; GO:0001641; GO:0005246; GO:0005886; GO:0007216; GO:0010467; GO:0014069; GO:0019233; GO:0030424; GO:0042734; GO:0043005; GO:0043197; GO:0045211; GO:0050804; GO:0051966; GO:0097110; GO:0097449; GO:0098794; GO:0098978; GO:0099170 36568 XM_029349014.2 212 0 26 47 0 P58307 1.57e-31 Orexin/Hypocretin receptor type 1 (Hypocretin receptor type 1) (Orexin receptor type 1) (Ox-1-R) (Ox1-R) (Ox1R) Mus musculus (Mouse) feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0004930; GO:0005886; GO:0007186; GO:0007218; GO:0007631; GO:0016499; GO:0017046; GO:0051480; GO:0070374 36569 XR_006392651.1 0 13 11 33 12 NA NA NA NA NA NA 36570 XM_029323502.2 69 30 35 55 0 O46564 1.8e-25 Bone morphogenetic protein 2 (BMP-2) Oryctolagus cuniculus (Rabbit) BMP signaling pathway [GO:0030509]; BMP signaling pathway involved in heart induction [GO:0003130]; cardiac epithelial to mesenchymal transition [GO:0060317]; cardiocyte differentiation [GO:0035051]; cartilage development [GO:0051216]; epithelial to mesenchymal transition [GO:0001837]; mesenchymal cell differentiation [GO:0048762]; negative regulation of cardiac muscle cell differentiation [GO:2000726]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of Wnt signaling pathway involved in heart development [GO:0003308]; osteoblast differentiation [GO:0001649]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone mineralization [GO:0030501]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of cartilage development [GO:0061036]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ossification [GO:0045778]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of phosphatase activity [GO:0010922]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; SMAD protein signal transduction [GO:0060395]; telencephalon development [GO:0021537] GO:0000122; GO:0001649; GO:0001837; GO:0001934; GO:0001938; GO:0003130; GO:0003308; GO:0005125; GO:0005615; GO:0008083; GO:0008285; GO:0009986; GO:0010862; GO:0010922; GO:0019211; GO:0021537; GO:0030501; GO:0030509; GO:0035051; GO:0043065; GO:0045778; GO:0045786; GO:0045892; GO:0045944; GO:0046332; GO:0048762; GO:0051216; GO:0060317; GO:0060389; GO:0060395; GO:0061036; GO:0070700; GO:1900159; GO:2000726 36571 XM_029333850.2 18 2 27 23 66 NA NA NA NA NA NA 36572 XR_006393186.1 4 11 0 8 9 NA NA NA NA NA NA 36573 XM_029336906.2 1284 530 697 1011 981 Q9WYX8 1.14e-36 Uncharacterized protein TM_0508 Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) DNA recombination [GO:0006310]; DNA synthesis involved in DNA repair [GO:0000731]; DNA-templated DNA replication [GO:0006261] GO:0000731; GO:0003677; GO:0005524; GO:0006261; GO:0006310; GO:0008047; GO:0009378; GO:0017116 36574 XM_029350044.2 519 186 432 416 278 Q12791 0 Calcium-activated potassium channel subunit alpha-1 (BK channel) (BKCA alpha) (Calcium-activated potassium channel, subfamily M subunit alpha-1) (K(VCA)alpha) (KCa1.1) (Maxi K channel) (MaxiK) (Slo-alpha) (Slo1) (Slowpoke homolog) (Slo homolog) (hSlo) Homo sapiens (Human) cellular potassium ion homeostasis [GO:0030007]; micturition [GO:0060073]; negative regulation of cell volume [GO:0045794]; positive regulation of apoptotic process [GO:0043065]; potassium ion transport [GO:0006813]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; relaxation of vascular associated smooth muscle [GO:0060087]; response to calcium ion [GO:0051592]; response to carbon monoxide [GO:0034465]; response to hypoxia [GO:0001666]; response to osmotic stress [GO:0006970]; smooth muscle contraction involved in micturition [GO:0060083] GO:0001666; GO:0003779; GO:0005249; GO:0005886; GO:0005901; GO:0006813; GO:0006970; GO:0008076; GO:0015269; GO:0016020; GO:0016324; GO:0030007; GO:0034465; GO:0034765; GO:0042391; GO:0042802; GO:0043065; GO:0045211; GO:0045794; GO:0046872; GO:0051592; GO:0060072; GO:0060073; GO:0060083; GO:0060087 36575 XM_029350667.2 3 0 0 0 8 NA NA NA NA NA NA 36576 XM_029345258.2 5895 5809 3723 4137 2560 NA NA NA NA NA NA 36577 XM_044324552.1 0 0 0 21 0 H1AFJ5 3.19e-39 Amiloride-sensitive sodium channel subunit alpha (Alpha-NaCH) (Epithelial Na(+) channel subunit alpha) (Alpha-ENaC) (Nonvoltage-gated sodium channel 1 subunit alpha) (SCNEA) Neoceratodus forsteri (Australian lungfish) (Ceratodus forsteri) sodium ion transmembrane transport [GO:0035725] GO:0001669; GO:0005737; GO:0015280; GO:0016324; GO:0031514; GO:0034706; GO:0035725 36578 XM_029353531.2 9 0 0 13 6 NA NA NA NA NA NA 36579 XM_044327602.1 0 0 0 0 9 NA NA NA NA NA NA 36580 XM_029350814.2 13019 9550 5851 8373 8464 P35565 4.11e-161 Calnexin Rattus norvegicus (Rat) aging [GO:0007568]; clathrin-dependent endocytosis [GO:0072583]; protein folding [GO:0006457]; synaptic vesicle endocytosis [GO:0048488]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0005509; GO:0005737; GO:0005783; GO:0005789; GO:0005790; GO:0005840; GO:0006457; GO:0007568; GO:0016020; GO:0030246; GO:0030424; GO:0030433; GO:0031965; GO:0032839; GO:0032991; GO:0034185; GO:0035255; GO:0042470; GO:0043025; GO:0043197; GO:0044233; GO:0044322; GO:0045202; GO:0045211; GO:0048488; GO:0048787; GO:0051082; GO:0072583; GO:0098793; GO:0098978 36581 XM_044309684.1 252 58 77 207 213 Q80XJ3 1.8e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 36582 XM_044319247.1 1599 970 1494 842 818 Q9R0R1 1.57e-58 Melanotransferrin (Membrane-bound transferrin-like protein p97) (MTf) (CD antigen CD228) Mus musculus (Mouse) iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of plasminogen activation [GO:0010756] GO:0005506; GO:0005615; GO:0005769; GO:0005886; GO:0006826; GO:0009986; GO:0010756; GO:0055037; GO:0055072; GO:0090091; GO:1900025 36583 XM_044319247.1 1599 970 1494 842 818 Q9R0R1 9.42e-51 Melanotransferrin (Membrane-bound transferrin-like protein p97) (MTf) (CD antigen CD228) Mus musculus (Mouse) iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of plasminogen activation [GO:0010756] GO:0005506; GO:0005615; GO:0005769; GO:0005886; GO:0006826; GO:0009986; GO:0010756; GO:0055037; GO:0055072; GO:0090091; GO:1900025 36584 XM_029329298.2 0 0 9 0 0 NA NA NA NA NA NA 36585 XM_029358350.2 2724 1779 1723 2695 2657 A7SK48 0 Eukaryotic translation initiation factor 3 subunit A (eIF3a) (Eukaryotic translation initiation factor 3 subunit 10) Nematostella vectensis (Starlet sea anemone) formation of cytoplasmic translation initiation complex [GO:0001732]; translation reinitiation [GO:0002188] GO:0001732; GO:0002188; GO:0003729; GO:0003743; GO:0016282; GO:0033290; GO:0043614; GO:0071540; GO:0071541 36586 XM_044328456.1 388 442 535 813 1024 Q5REL1 1.14e-171 cAMP-dependent protein kinase type I-alpha regulatory subunit Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) regulation of protein phosphorylation [GO:0001932] GO:0001932; GO:0005737; GO:0005886; GO:0005952; GO:0008603; GO:0030552 36587 XM_044328647.1 0 105 22 55 320 Q4V7Q8 7.23e-21 Transmembrane protein 220 Xenopus laevis (African clawed frog) NA GO:0016020 36588 XR_006395217.1 59 35 51 70 175 NA NA NA NA NA NA 36589 XM_044326771.1 0 0 58 0 0 B0BM20 8.79e-42 Enolase 4 (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) glycolytic process [GO:0006096] GO:0000015; GO:0000287; GO:0004634; GO:0006096 36590 XM_044310439.1 23 4 0 29 18 NA NA NA NA NA NA 36591 XM_029342119.2 0 0 0 70 0 P21804 3.35e-58 Fibroblast growth factor receptor 1 (FGFR-1) (bFGF-R-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (Tyrosine kinase receptor CEK1) Gallus gallus (Chicken) epicardial cell to mesenchymal cell transition [GO:0003347]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phospholipase C activity [GO:0010863]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0003347; GO:0004714; GO:0005007; GO:0005524; GO:0005634; GO:0005829; GO:0005886; GO:0007169; GO:0008201; GO:0008284; GO:0010863; GO:0017134; GO:0018108; GO:0031410; GO:0033674; GO:0043235; GO:0043406; GO:0045597; GO:0045893 36592 XM_029342119.2 0 0 0 70 0 P21804 3.35e-58 Fibroblast growth factor receptor 1 (FGFR-1) (bFGF-R-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (Tyrosine kinase receptor CEK1) Gallus gallus (Chicken) epicardial cell to mesenchymal cell transition [GO:0003347]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phospholipase C activity [GO:0010863]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0003347; GO:0004714; GO:0005007; GO:0005524; GO:0005634; GO:0005829; GO:0005886; GO:0007169; GO:0008201; GO:0008284; GO:0010863; GO:0017134; GO:0018108; GO:0031410; GO:0033674; GO:0043235; GO:0043406; GO:0045597; GO:0045893 36593 XM_029339184.2 13 32 36 0 9 NA NA NA NA NA NA 36594 XM_029341805.2 89 0 0 147 577 NA NA NA NA NA NA 36595 XM_029350589.2 1912 2372 1198 1507 408 Q6XP49 4.43e-74 Zinc finger protein GLIS3 (GLI-similar 3) Mus musculus (Mouse) negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366] GO:0000122; GO:0000977; GO:0000978; GO:0000981; GO:0001227; GO:0001228; GO:0003677; GO:0003700; GO:0005634; GO:0006357; GO:0006366; GO:0045944; GO:0046872 36596 XR_006394063.1 0 0 8 0 13 NA NA NA NA NA NA 36597 XM_044324801.1 0 5 0 4 9 NA NA NA NA NA NA 36598 XR_006392941.1 41 2 25 5 151 NA NA NA NA NA NA 36599 XM_029344911.2 20 0 0 0 0 Q54KD0 5.3e-69 TPR repeat-containing protein DDB_G0287407 Dictyostelium discoideum (Social amoeba) NA NA 36600 XM_029331930.2 53 3 34 0 136 NA NA NA NA NA NA 36601 XM_044311083.1 16 11 14 22 35 NA NA NA NA NA NA 36602 XR_006391453.1 0 55 73 39 0 NA NA NA NA NA NA 36603 XM_029327820.2 975 890 758 947 487 Q96DM1 1.04e-49 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 36604 XM_029336575.2 0 31 0 0 10 NA NA NA NA NA NA 36605 XR_006394807.1 146 141 121 171 188 NA NA NA NA NA NA 36606 XR_003825611.2 524 323 287 841 0 NA NA NA NA NA NA 36607 XR_006394616.1 78 45 18 43 20 NA NA NA NA NA NA 36608 XM_029333646.2 224 331 134 152 219 Q5R592 2.9e-49 DNA-directed RNA polymerases I, II, and III subunit RPABC2 (RNA polymerases I, II, and III subunit ABC2) (DNA-directed RNA polymerase II subunit F) (RPB6 homolog) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) transcription by RNA polymerase II [GO:0006366] GO:0003677; GO:0003899; GO:0005634; GO:0005665; GO:0006366 36609 XM_044321152.1 157 45 182 129 117 NA NA NA NA NA NA 36610 XM_044323623.1 59 54 37 102 103 NA NA NA NA NA NA 36611 XR_006395068.1 456 109 80 646 477 NA NA NA NA NA NA 36612 XM_029356796.2 48 66 28 27 80 Q6P3S6 2.94e-64 F-box only protein 42 (Just one F-box and Kelch domain-containing protein) Homo sapiens (Human) NA GO:0019005; GO:1990756 36613 XM_044317984.1 0 34 0 0 0 NA NA NA NA NA NA 36614 XR_003828369.2 97 107 65 90 52 NA NA NA NA NA NA 36615 XM_029353947.2 84 60 43 69 95 NA NA NA NA NA NA 36616 XM_029333002.2 655 652 875 670 467 NA NA NA NA NA NA 36617 XM_044309125.1 24 53 40 0 13 C3YZ51 1.97e-173 Ubiquitin-like modifier-activating enzyme 5 (Ubiquitin-activating enzyme 5) Branchiostoma floridae (Florida lancelet) (Amphioxus) protein modification by small protein conjugation [GO:0032446]; protein ufmylation [GO:0071569] GO:0005524; GO:0005737; GO:0005829; GO:0032446; GO:0046872; GO:0071566; GO:0071569 36618 XM_044307766.1 354 0 0 284 813 P14543 1.74e-87 Nidogen-1 (NID-1) (Entactin) Homo sapiens (Human) basement membrane organization [GO:0071711]; cell-matrix adhesion [GO:0007160]; glomerular basement membrane development [GO:0032836]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of muscle cell differentiation [GO:0051149]; regulation of basement membrane organization [GO:0110011] GO:0005201; GO:0005509; GO:0005518; GO:0005576; GO:0005604; GO:0005886; GO:0007160; GO:0010811; GO:0032836; GO:0043236; GO:0043237; GO:0043394; GO:0045785; GO:0051149; GO:0062023; GO:0070062; GO:0071711; GO:0098637; GO:0110011; GO:2001046 36619 XM_044307766.1 354 0 0 284 813 P14543 3.63e-43 Nidogen-1 (NID-1) (Entactin) Homo sapiens (Human) basement membrane organization [GO:0071711]; cell-matrix adhesion [GO:0007160]; glomerular basement membrane development [GO:0032836]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of muscle cell differentiation [GO:0051149]; regulation of basement membrane organization [GO:0110011] GO:0005201; GO:0005509; GO:0005518; GO:0005576; GO:0005604; GO:0005886; GO:0007160; GO:0010811; GO:0032836; GO:0043236; GO:0043237; GO:0043394; GO:0045785; GO:0051149; GO:0062023; GO:0070062; GO:0071711; GO:0098637; GO:0110011; GO:2001046 36620 XM_044307766.1 354 0 0 284 813 P14543 4.11e-22 Nidogen-1 (NID-1) (Entactin) Homo sapiens (Human) basement membrane organization [GO:0071711]; cell-matrix adhesion [GO:0007160]; glomerular basement membrane development [GO:0032836]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of muscle cell differentiation [GO:0051149]; regulation of basement membrane organization [GO:0110011] GO:0005201; GO:0005509; GO:0005518; GO:0005576; GO:0005604; GO:0005886; GO:0007160; GO:0010811; GO:0032836; GO:0043236; GO:0043237; GO:0043394; GO:0045785; GO:0051149; GO:0062023; GO:0070062; GO:0071711; GO:0098637; GO:0110011; GO:2001046 36621 XM_044328241.1 13 34 3 29 34 NA NA NA NA NA NA 36622 XM_029343210.2 0 0 0 15 0 Q9Z142 6.19e-63 Transmembrane protein 33 (Protein DB83) Rattus norvegicus (Rat) endoplasmic reticulum tubular network organization [GO:0071786]; innate immune response [GO:0045087]; membrane organization [GO:0061024]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of PERK-mediated unfolded protein response [GO:1903899]; regulation of endoplasmic reticulum tubular network organization [GO:1903371]; response to endoplasmic reticulum stress [GO:0034976] GO:0005635; GO:0005783; GO:0005789; GO:0034976; GO:0042470; GO:0045087; GO:0061024; GO:0071786; GO:1903371; GO:1903896; GO:1903899 36623 XR_006396262.1 264 33 3 104 15 NA NA NA NA NA NA 36624 XR_006394587.1 306 40 11 14 39 NA NA NA NA NA NA 36625 XM_029336395.2 4 2 0 9 14 NA NA NA NA NA NA 36626 XM_044327942.1 215 108 177 207 368 Q5R8Y3 2.51e-31 Regulation of nuclear pre-mRNA domain-containing protein 1A (Cyclin-dependent kinase inhibitor 2B-related protein) (p15INK4B-related protein) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) dephosphorylation of RNA polymerase II C-terminal domain [GO:0070940] GO:0005634; GO:0016591; GO:0070940 36627 XR_006392015.1 247 132 77 135 130 NA NA NA NA NA NA 36628 XM_029331285.2 153 179 102 169 122 Q5UAW9 4.57e-35 G-protein coupled receptor 157 Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; circadian behavior [GO:0048512]; G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; radial glial cell differentiation [GO:0060019] GO:0004930; GO:0005886; GO:0007166; GO:0007186; GO:0007189; GO:0048512; GO:0051482; GO:0060019; GO:0060170 36629 XM_029324805.2 0 20 0 0 0 P98198 0 Phospholipid-transporting ATPase ID (EC 7.6.2.1) (ATPase class I type 8B member 2) (P4-ATPase flippase complex alpha subunit ATP8B2) Homo sapiens (Human) Golgi organization [GO:0007030]; ion transmembrane transport [GO:0034220]; phospholipid translocation [GO:0045332] GO:0000287; GO:0005524; GO:0005730; GO:0005789; GO:0005794; GO:0005802; GO:0005829; GO:0005886; GO:0007030; GO:0016887; GO:0034220; GO:0045332; GO:0090554; GO:0140326; GO:0140345; GO:1990531 36630 XM_029333676.2 685 480 445 0 971 A2A9C3 0 KICSTOR complex protein SZT2 (Seizure threshold 2 protein) (Transcript increased in glutamate resistance) (TIGR) Mus musculus (Mouse) cellular response to amino acid starvation [GO:0034198]; cellular response to glucose starvation [GO:0042149]; central nervous system development [GO:0007417]; corpus callosum morphogenesis [GO:0021540]; negative regulation of TORC1 signaling [GO:1904262]; pigmentation [GO:0043473]; post-embryonic development [GO:0009791]; protein localization to lysosome [GO:0061462]; regulation of superoxide dismutase activity [GO:1901668]; response to nutrient levels [GO:0031667] GO:0005765; GO:0005777; GO:0007417; GO:0009791; GO:0021540; GO:0031667; GO:0034198; GO:0042149; GO:0043473; GO:0061462; GO:0061700; GO:0140007; GO:1901668; GO:1904262; GO:1990130 36631 XM_029333676.2 685 480 445 0 971 A2A9C3 5.56e-91 KICSTOR complex protein SZT2 (Seizure threshold 2 protein) (Transcript increased in glutamate resistance) (TIGR) Mus musculus (Mouse) cellular response to amino acid starvation [GO:0034198]; cellular response to glucose starvation [GO:0042149]; central nervous system development [GO:0007417]; corpus callosum morphogenesis [GO:0021540]; negative regulation of TORC1 signaling [GO:1904262]; pigmentation [GO:0043473]; post-embryonic development [GO:0009791]; protein localization to lysosome [GO:0061462]; regulation of superoxide dismutase activity [GO:1901668]; response to nutrient levels [GO:0031667] GO:0005765; GO:0005777; GO:0007417; GO:0009791; GO:0021540; GO:0031667; GO:0034198; GO:0042149; GO:0043473; GO:0061462; GO:0061700; GO:0140007; GO:1901668; GO:1904262; GO:1990130 36632 XM_029333676.2 685 480 445 0 971 A2A9C3 1.05e-59 KICSTOR complex protein SZT2 (Seizure threshold 2 protein) (Transcript increased in glutamate resistance) (TIGR) Mus musculus (Mouse) cellular response to amino acid starvation [GO:0034198]; cellular response to glucose starvation [GO:0042149]; central nervous system development [GO:0007417]; corpus callosum morphogenesis [GO:0021540]; negative regulation of TORC1 signaling [GO:1904262]; pigmentation [GO:0043473]; post-embryonic development [GO:0009791]; protein localization to lysosome [GO:0061462]; regulation of superoxide dismutase activity [GO:1901668]; response to nutrient levels [GO:0031667] GO:0005765; GO:0005777; GO:0007417; GO:0009791; GO:0021540; GO:0031667; GO:0034198; GO:0042149; GO:0043473; GO:0061462; GO:0061700; GO:0140007; GO:1901668; GO:1904262; GO:1990130 36633 XR_006397403.1 2 0 17 9 86 NA NA NA NA NA NA 36634 XM_029353310.2 9 0 0 2 8 NA NA NA NA NA NA 36635 XM_029326765.2 0 0 7 9 9 NA NA NA NA NA NA 36636 XR_006393729.1 0 0 2 8 28 NA NA NA NA NA NA 36637 XM_029328522.2 17 23 32 59 52 Q8IZU8 0 Dermatan-sulfate epimerase-like protein (EC 5.1.-.-) Homo sapiens (Human) chondroitin sulfate metabolic process [GO:0030204]; dermatan sulfate biosynthetic process [GO:0030208]; dermatan sulfate metabolic process [GO:0030205] GO:0000139; GO:0008146; GO:0030204; GO:0030205; GO:0030208; GO:0047757 36638 XM_029328522.2 17 23 32 59 52 Q8IZU8 3.16e-25 Dermatan-sulfate epimerase-like protein (EC 5.1.-.-) Homo sapiens (Human) chondroitin sulfate metabolic process [GO:0030204]; dermatan sulfate biosynthetic process [GO:0030208]; dermatan sulfate metabolic process [GO:0030205] GO:0000139; GO:0008146; GO:0030204; GO:0030205; GO:0030208; GO:0047757 36639 XM_029350383.2 872 410 242 452 190 Q99020 2.25e-49 Heterogeneous nuclear ribonucleoprotein A/B (hnRNP A/B) (CArG-binding factor-A) (CBF-A) Mus musculus (Mouse) epithelial to mesenchymal transition [GO:0001837]; mRNA modification [GO:0016556]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA demethylation [GO:1901537]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of cellular localization [GO:0060341]; regulation of gene expression [GO:0010468]; regulation of intracellular mRNA localization [GO:1904580] GO:0000122; GO:0001837; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0010468; GO:0016556; GO:0030425; GO:0044877; GO:0045293; GO:0045893; GO:0060341; GO:0071598; GO:0090575; GO:0099523; GO:1901537; GO:1904580; GO:1990124; GO:1990837; GO:1990904; GO:2000623 36640 XR_003826358.2 7 30 4 28 40 NA NA NA NA NA NA 36641 XM_029340522.2 205 193 55 90 38 NA NA NA NA NA NA 36642 XM_029352284.2 95 108 98 307 83 NA NA NA NA NA NA 36643 XM_044310002.1 62 3 96 17 142 NA NA NA NA NA NA 36644 XM_029344412.2 20 15 25 89 53 Q28997 1.65e-27 Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor) Sus scrofa (Pig) activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; blood vessel diameter maintenance [GO:0097746]; desensitization of G protein-coupled receptor signaling pathway by arrestin [GO:0002032]; positive regulation of autophagosome maturation [GO:1901098]; positive regulation of lipophagy [GO:1904504]; positive regulation of MAPK cascade [GO:0043410]; receptor-mediated endocytosis [GO:0006898]; regulation of smooth muscle contraction [GO:0006940] GO:0002032; GO:0004941; GO:0005769; GO:0005794; GO:0005886; GO:0006898; GO:0006940; GO:0007189; GO:0007190; GO:0042803; GO:0043235; GO:0043410; GO:0051380; GO:0097746; GO:1901098; GO:1904504 36645 XM_029332008.2 25 26 0 0 99 NA NA NA NA NA NA 36646 XM_029339841.2 356 55 156 181 177 Q149N8 0 E3 ubiquitin-protein ligase SHPRH (EC 2.3.2.27) (EC 3.6.4.-) (RING-type E3 ubiquitin transferase SHPRH) (SNF2, histone-linker, PHD and RING finger domain-containing helicase) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; nucleosome assembly [GO:0006334]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567] GO:0000209; GO:0000786; GO:0003677; GO:0004386; GO:0004842; GO:0005524; GO:0005654; GO:0006281; GO:0006334; GO:0006974; GO:0016567; GO:0016787; GO:0031625; GO:0046872; GO:0061630; GO:0140658 36647 XM_044323573.1 36 18 8 27 8 NA NA NA NA NA NA 36648 XM_044310660.1 28 32 39 42 60 NA NA NA NA NA NA 36649 XM_029337636.2 31 11 22 28 20 NA NA NA NA NA NA 36650 XM_044328972.1 13 0 27 28 47 NA NA NA NA NA NA 36651 XM_044311217.1 0 0 0 0 85 P46023 9.31e-112 G-protein coupled receptor GRL101 Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004930; GO:0005886 36652 XM_044328954.1 43 20 47 56 65 NA NA NA NA NA NA 36653 XM_044327068.1 120 6 81 88 101 Q9EP86 4.33e-25 Neuropeptide FF receptor 1 (G-protein coupled receptor 147) (RFamide-related peptide receptor OT7T022) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0005886; GO:0005929; GO:0007186; GO:0008188; GO:0042277 36654 XM_029341815.2 4 54 53 52 30 Q5TFE4 1.4e-91 5'-nucleotidase domain-containing protein 1 (EC 3.1.3.-) Homo sapiens (Human) NA GO:0008253; GO:0046872 36655 XR_006396532.1 2074 6819 2723 6086 5043 NA NA NA NA NA NA 36656 XM_044309050.1 88 49 23 67 91 NA NA NA NA NA NA 36657 XM_044328530.1 402 340 192 280 201 Q8H1F7 1.24e-34 Isopentenyl phosphate kinase (AtIPK) (IPK) (EC 2.7.4.26) Arabidopsis thaliana (Mouse-ear cress) phosphorylation [GO:0016310]; terpenoid biosynthetic process [GO:0016114] GO:0005524; GO:0005829; GO:0016114; GO:0016301; GO:0016310; GO:0102043 36658 XM_044324310.1 215 146 124 165 81 Q568Q0 2.34e-36 8-oxo-dGDP phosphatase NUDT18 (EC 3.6.1.58) (2-hydroxy-dADP phosphatase) (7,8-dihydro-8-oxoguanine phosphatase) (Nucleoside diphosphate-linked moiety X motif 18) (Nudix motif 18) Danio rerio (Zebrafish) (Brachydanio rerio) dADP catabolic process [GO:0046057]; dGDP catabolic process [GO:0046067]; GDP catabolic process [GO:0046712] GO:0000287; GO:0044715; GO:0044716; GO:0044717; GO:0046057; GO:0046067; GO:0046712 36659 XM_044327482.1 81 95 59 296 167 NA NA NA NA NA NA 36660 XM_044308505.1 0 0 27 0 24 NA NA NA NA NA NA 36661 XR_006395879.1 66 48 98 110 71 NA NA NA NA NA NA 36662 XM_044323368.1 34 37 37 34 110 Q5ZMC3 5.1e-52 WD repeat, SAM and U-box domain-containing protein 1 Gallus gallus (Chicken) NA GO:0004842 36663 XR_006397951.1 43 29 67 85 225 NA NA NA NA NA NA 36664 XM_044326586.1 54 1329 276 2352 435 Q80TR8 0 DDB1- and CUL4-associated factor 1 (Serine/threonine-protein kinase VPRBP) (EC 2.7.11.1) Mus musculus (Mouse) B cell differentiation [GO:0030183]; cell competition in a multicellular organism [GO:0035212]; chromatin organization [GO:0006325]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phosphorylation [GO:0016310]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; V(D)J recombination [GO:0033151] GO:0000122; GO:0001650; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0006325; GO:0008180; GO:0016310; GO:0016567; GO:0030183; GO:0030331; GO:0033151; GO:0035212; GO:0043687; GO:0080008; GO:0106310; GO:1990244 36665 XM_044326586.1 54 1329 276 2352 435 Q80TR8 1.09e-116 DDB1- and CUL4-associated factor 1 (Serine/threonine-protein kinase VPRBP) (EC 2.7.11.1) Mus musculus (Mouse) B cell differentiation [GO:0030183]; cell competition in a multicellular organism [GO:0035212]; chromatin organization [GO:0006325]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phosphorylation [GO:0016310]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; V(D)J recombination [GO:0033151] GO:0000122; GO:0001650; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0006325; GO:0008180; GO:0016310; GO:0016567; GO:0030183; GO:0030331; GO:0033151; GO:0035212; GO:0043687; GO:0080008; GO:0106310; GO:1990244 36666 XM_044312812.1 333 194 90 198 3 Q11011 0 Puromycin-sensitive aminopeptidase (PSA) (EC 3.4.11.14) (Cytosol alanyl aminopeptidase) (AAP-S) Mus musculus (Mouse) cellular response to hypoxia [GO:0071456]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508] GO:0004177; GO:0005634; GO:0005737; GO:0005829; GO:0006508; GO:0008270; GO:0042277; GO:0043171; GO:0070006; GO:0071456 36667 XM_029354261.2 355 398 234 239 405 NA NA NA NA NA NA 36668 XR_006396356.1 0 1 0 0 6 NA NA NA NA NA NA 36669 XM_044321549.1 26 3 4 0 123 NA NA NA NA NA NA 36670 XM_044323809.1 0 0 740 465 407 Q4LDE5 0 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 36671 XM_044323809.1 0 0 740 465 407 Q4LDE5 6.4e-177 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 36672 XM_044323809.1 0 0 740 465 407 Q4LDE5 1.2e-174 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 36673 XM_044323809.1 0 0 740 465 407 Q4LDE5 1.48e-171 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 36674 XM_044323809.1 0 0 740 465 407 Q4LDE5 4.39e-163 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 36675 XM_044323809.1 0 0 740 465 407 Q4LDE5 5.22e-130 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 36676 XM_044316481.1 6 0 0 4 0 O60290 1.04e-51 Zinc finger protein 862 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006355; GO:0046872; GO:0046983 36677 XM_044316853.1 874 1335 411 1803 1064 NA NA NA NA NA NA 36678 XR_003827077.2 108 78 87 203 160 NA NA NA NA NA NA 36679 XM_029346006.2 46 97 64 70 123 NA NA NA NA NA NA 36680 XM_044309960.1 0 0 8 0 3 NA NA NA NA NA NA 36681 XM_029337484.2 33 0 0 39 12 P16065 0 Speract receptor (EC 4.6.1.2) (Guanylate cyclase) Strongylocentrotus purpuratus (Purple sea urchin) cGMP biosynthetic process [GO:0006182]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]; receptor guanylyl cyclase signaling pathway [GO:0007168]; signal transduction [GO:0007165] GO:0001653; GO:0004383; GO:0004672; GO:0005524; GO:0005525; GO:0005886; GO:0006182; GO:0006468; GO:0007165; GO:0007168; GO:0035556 36682 XM_044310161.1 58 17 33 24 19 G5EBQ8 3.72e-120 Chitin synthase chs-2 (EC 2.4.1.16) (Chitin-UDP acetyl-glucosaminyl transferase chs-2) Caenorhabditis elegans cell wall chitin biosynthetic process [GO:0006038]; chitin biosynthetic process [GO:0006031]; positive regulation of nematode larval development [GO:0061063] GO:0004100; GO:0005886; GO:0006031; GO:0006038; GO:0030428; GO:0061063; GO:0071944 36683 XM_029356747.2 933 862 540 832 1523 P54797 2.5e-60 Transport and Golgi organization 2 homolog (Ser/Thr-rich protein T10 in DGCR region) Mus musculus (Mouse) Golgi organization [GO:0007030]; protein secretion [GO:0009306] GO:0005737; GO:0005739; GO:0005794; GO:0005829; GO:0007030; GO:0009306 36684 XM_029348694.2 852 562 316 833 883 NA NA NA NA NA NA 36685 XR_006393944.1 2395 1740 1275 461 963 NA NA NA NA NA NA 36686 XM_029338159.2 555 357 490 1298 1493 NA NA NA NA NA NA 36687 XM_044322811.1 20 0 11 16 9 NA NA NA NA NA NA 36688 XM_029356711.2 202 149 46 152 119 Q9DG67 0 DNA repair and recombination protein RAD54B (EC 3.6.4.-) (RAD54 homolog B) Gallus gallus (Chicken) DNA repair [GO:0006281] GO:0003677; GO:0004386; GO:0005524; GO:0005634; GO:0006281; GO:0016787; GO:0140658 36689 XM_044311022.1 143 193 274 151 143 Q9UJG1 8.57e-49 Motile sperm domain-containing protein 1 Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000122; GO:0000139; GO:0005634; GO:0005737; GO:0005789; GO:0030154; GO:0045944; GO:0048471 36690 XM_029333933.2 606 236 124 340 631 NA NA NA NA NA NA 36691 XM_044326367.1 16 13 27 10 7 P30974 2.5e-30 Tachykinin-like peptides receptor 86C (NKD) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; inter-male aggressive behavior [GO:0002121]; neuropeptide signaling pathway [GO:0007218]; tachykinin receptor signaling pathway [GO:0007217] GO:0002121; GO:0004995; GO:0005886; GO:0007186; GO:0007217; GO:0007218; GO:0008188; GO:0016020 36692 XM_044323176.1 1 1 0 74 0 NA NA NA NA NA NA 36693 XM_044317727.1 56 10 1 29 33 A7RWP6 7.81e-60 Eukaryotic translation initiation factor 3 subunit E (eIF3e) (Eukaryotic translation initiation factor 3 subunit 6) Nematostella vectensis (Starlet sea anemone) formation of cytoplasmic translation initiation complex [GO:0001732]; translational initiation [GO:0006413] GO:0001732; GO:0003743; GO:0005634; GO:0005852; GO:0006413; GO:0016282; GO:0033290; GO:0071540 36694 XM_044317727.1 56 10 1 29 33 A7RWP6 7.81e-60 Eukaryotic translation initiation factor 3 subunit E (eIF3e) (Eukaryotic translation initiation factor 3 subunit 6) Nematostella vectensis (Starlet sea anemone) formation of cytoplasmic translation initiation complex [GO:0001732]; translational initiation [GO:0006413] GO:0001732; GO:0003743; GO:0005634; GO:0005852; GO:0006413; GO:0016282; GO:0033290; GO:0071540 36695 XM_044316888.1 594 488 206 942 689 NA NA NA NA NA NA 36696 XM_029326168.2 0 6 4 1 11 NA NA NA NA NA NA 36697 XM_044328551.1 10 51 11 20 11 Q7L5D6 4.08e-78 Golgi to ER traffic protein 4 homolog (Conserved edge-expressed protein) (Transmembrane domain recognition complex 35 kDa subunit) (TRC35) Homo sapiens (Human) cytoplasmic sequestering of protein [GO:0051220]; maintenance of unfolded protein involved in ERAD pathway [GO:1904378]; post-translational protein targeting to endoplasmic reticulum membrane [GO:0006620]; protein insertion into ER membrane [GO:0045048]; regulation of protein stability [GO:0031647]; tail-anchored membrane protein insertion into ER membrane [GO:0071816]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0005654; GO:0005694; GO:0005730; GO:0005737; GO:0005829; GO:0006511; GO:0006620; GO:0031647; GO:0045048; GO:0051087; GO:0051220; GO:0071816; GO:0071818; GO:1904378 36698 XM_029323459.2 69 0 70 0 0 NA NA NA NA NA NA 36699 XM_044325412.1 0 0 17 0 10 NA NA NA NA NA NA 36700 XM_029333593.2 1008 1075 713 1195 1074 P70187 0 Hippocampus abundant transcript 1 protein (Major facilitator superfamily domain-containing 14A) Mus musculus (Mouse) acrosome assembly [GO:0001675]; sperm mitochondrion organization [GO:0030382]; spermatid development [GO:0007286]; spermatid nucleus differentiation [GO:0007289]; spermatogenesis [GO:0007283] GO:0001675; GO:0007283; GO:0007286; GO:0007289; GO:0016020; GO:0022857; GO:0030382 36701 XM_029324070.2 195 152 125 120 144 Q803A6 8.41e-171 Mini-chromosome maintenance complex-binding protein (MCM-BP) (MCM-binding protein) Danio rerio (Zebrafish) (Brachydanio rerio) cell division [GO:0051301]; DNA-templated DNA replication [GO:0006261]; sister chromatid cohesion [GO:0007062] GO:0003682; GO:0005634; GO:0006261; GO:0007062; GO:0051301 36702 XM_044318603.1 2240 1173 629 897 1357 NA NA NA NA NA NA 36703 XM_029343786.2 615 394 375 549 450 NA NA NA NA NA NA 36704 XM_044328615.1 43 38 24 6 20 NA NA NA NA NA NA 36705 XR_006396522.1 13 21 12 13 38 NA NA NA NA NA NA 36706 XM_029323881.2 137 82 51 127 117 O15973 8.15e-21 Rhodopsin, GQ-coupled (GQ-rhodopsin) Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis) phototransduction [GO:0007602]; visual perception [GO:0007601] GO:0004930; GO:0005886; GO:0007601; GO:0007602; GO:0009881 36707 XM_044307680.1 2346 2224 997 567 1625 A2RRH5 2.79e-100 WD repeat-containing protein 27 Homo sapiens (Human) NA GO:0005654 36708 XM_044320831.1 220 266 430 48 204 Q8K3Z0 4.72e-25 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 36709 XM_044318378.1 30 1 16 1 15 NA NA NA NA NA NA 36710 XM_029327293.2 3303 2287 1752 2702 2719 NA NA NA NA NA NA 36711 XM_044321518.1 178 187 286 266 309 Q54RA4 5.06e-54 Probable iron/ascorbate oxidoreductase DDB_G0283291 (EC 1.14.-.-) Dictyostelium discoideum (Social amoeba) NA GO:0046872; GO:0051213 36712 XM_044309220.1 0 0 6 0 9 NA NA NA NA NA NA 36713 XM_029333714.2 596 398 271 481 542 Q9U518 3.84e-146 L-asparaginase (EC 3.5.1.1) (DiAsp) (L-asparagine amidohydrolase) Dirofilaria immitis (Canine heartworm) asparagine metabolic process [GO:0006528] GO:0004067; GO:0006528 36714 XM_029335481.2 15 33 6 17 19 O15439 0 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 36715 XR_006395324.1 8 1 1 22 34 NA NA NA NA NA NA 36716 XM_044324320.1 17 1 77 0 53 NA NA NA NA NA NA 36717 XM_029336270.2 1 1 5 0 9 NA NA NA NA NA NA 36718 XM_044307615.1 270 187 34 348 222 NA NA NA NA NA NA 36719 XM_044322321.1 49 17 31 5 49 P04323 1.13e-56 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 36720 XM_044311069.1 88 27 49 143 65 P16157 1.45e-65 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 36721 XM_044311069.1 88 27 49 143 65 P16157 5.67e-57 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 36722 XM_044311069.1 88 27 49 143 65 P16157 1.97e-51 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 36723 XM_044311069.1 88 27 49 143 65 P16157 4.64e-37 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 36724 XM_044311069.1 88 27 49 143 65 P16157 1.25e-28 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 36725 XM_044311069.1 88 27 49 143 65 P16157 3.02e-28 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 36726 XM_044312077.1 0 16 3 0 19 NA NA NA NA NA NA 36727 XM_029334547.2 805 204 291 810 289 NA NA NA NA NA NA 36728 XM_029350848.2 530 221 505 219 423 NA NA NA NA NA NA 36729 XM_044315012.1 97 4 307 70 271 Q13443 5.68e-72 Disintegrin and metalloproteinase domain-containing protein 9 (ADAM 9) (EC 3.4.24.-) (Cellular disintegrin-related protein) (Meltrin-gamma) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) Homo sapiens (Human) amyloid precursor protein catabolic process [GO:0042987]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell migration [GO:0016477]; cell-cell adhesion mediated by integrin [GO:0033631]; cell-matrix adhesion [GO:0007160]; cellular response to lipopolysaccharide [GO:0071222]; integrin-mediated signaling pathway [GO:0007229]; keratinocyte differentiation [GO:0030216]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; monocyte activation [GO:0042117]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of macrophage fusion [GO:0034241]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of protein secretion [GO:0050714]; protein processing [GO:0016485]; response to calcium ion [GO:0051592]; response to glucocorticoid [GO:0051384]; response to hydrogen peroxide [GO:0042542]; response to manganese ion [GO:0010042]; response to tumor necrosis factor [GO:0034612]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0004222; GO:0005080; GO:0005178; GO:0005518; GO:0005615; GO:0005925; GO:0006509; GO:0007155; GO:0007160; GO:0007179; GO:0007229; GO:0008237; GO:0009897; GO:0009986; GO:0010042; GO:0016477; GO:0016485; GO:0017124; GO:0030216; GO:0030335; GO:0031293; GO:0033627; GO:0033630; GO:0033631; GO:0034241; GO:0034612; GO:0042117; GO:0042542; GO:0042987; GO:0043236; GO:0043406; GO:0046872; GO:0050714; GO:0051044; GO:0051384; GO:0051549; GO:0051592; GO:0070062; GO:0071222; GO:1902945 36730 XM_044318913.1 16 13 23 12 11 C9D7C2 0 Voltage-dependent calcium channel type A subunit alpha-1 (Cacophony protein) Apis mellifera (Honeybee) regulation of ion transmembrane transport [GO:0034765] GO:0005245; GO:0005509; GO:0005891; GO:0034765 36731 XM_029357497.2 0 68 652 0 0 P23824 2.55e-70 GATA-binding factor 2 (GATA-2) (Transcription factor NF-E1b) Gallus gallus (Chicken) cell fate commitment [GO:0045165]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of angiogenesis [GO:0045766]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000122; GO:0000978; GO:0000981; GO:0001223; GO:0005634; GO:0008270; GO:0045165; GO:0045766; GO:0045944; GO:1902895 36732 XM_029331369.2 354 210 135 352 364 Q8AYS7 2.77e-104 Centromere protein I (CENP-I) Gallus gallus (Chicken) centromere complex assembly [GO:0034508] GO:0000776; GO:0005634; GO:0034508 36733 XM_029343041.2 2173 1972 1633 1926 1992 Q14166 4.31e-27 Tubulin--tyrosine ligase-like protein 12 (Inactive tubulin--tyrosine ligase-like protein 12) Homo sapiens (Human) innate immune response [GO:0045087]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; protein modification process [GO:0036211]; regulation of mitotic cell cycle [GO:0007346] GO:0005524; GO:0005634; GO:0005737; GO:0005815; GO:0005819; GO:0007346; GO:0015631; GO:0030496; GO:0036211; GO:0045087; GO:0060339; GO:1990889 36734 XM_029337685.2 1275 991 571 989 876 Q921W4 2.71e-82 Quinone oxidoreductase-like protein 1 (EC 1.-.-.-) (Quinone oxidoreductase homolog 1) (QOH-1) (Zeta-crystallin homolog) Mus musculus (Mouse) NA GO:0016491 36735 XM_044321951.1 0 0 0 3 39 NA NA NA NA NA NA 36736 XM_044306807.1 819 246 494 799 463 NA NA NA NA NA NA 36737 XR_006396060.1 1 7 2 14 15 NA NA NA NA NA NA 36738 XM_044307370.1 358 269 248 502 368 Q5S007 1.74e-64 Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin) Homo sapiens (Human) autophagy [GO:0006914]; calcium-mediated signaling [GO:0019722]; canonical Wnt signaling pathway [GO:0060070]; cellular response to dopamine [GO:1903351]; cellular response to manganese ion [GO:0071287]; cellular response to organic cyclic compound [GO:0071407]; cellular response to oxidative stress [GO:0034599]; cellular response to starvation [GO:0009267]; determination of adult lifespan [GO:0008340]; endocytosis [GO:0006897]; endoplasmic reticulum organization [GO:0007029]; excitatory postsynaptic potential [GO:0060079]; exploration behavior [GO:0035640]; Golgi organization [GO:0007030]; GTP metabolic process [GO:0046039]; intracellular distribution of mitochondria [GO:0048312]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; locomotory exploration behavior [GO:0035641]; lysosome organization [GO:0007040]; MAPK cascade [GO:0000165]; mitochondrion localization [GO:0051646]; mitochondrion organization [GO:0007005]; negative regulation of autophagosome assembly [GO:1902902]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of GTPase activity [GO:0034260]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of late endosome to lysosome transport [GO:1902823]; negative regulation of macroautophagy [GO:0016242]; negative regulation of neuron death [GO:1901215]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein binding [GO:0032091]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein processing [GO:0010955]; negative regulation of protein processing involved in protein targeting to mitochondrion [GO:1903217]; negative regulation of protein targeting to mitochondrion [GO:1903215]; negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation [GO:1903125]; neuromuscular junction development [GO:0007528]; neuron death [GO:0070997]; neuron projection arborization [GO:0140058]; neuron projection morphogenesis [GO:0048812]; olfactory bulb development [GO:0021772]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; phosphorylation [GO:0016310]; positive regulation of autophagy [GO:0010508]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of dopamine receptor signaling pathway [GO:0060161]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of programmed cell death [GO:0043068]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein autoubiquitination [GO:1902499]; positive regulation of protein binding [GO:0032092]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; positive regulation of tumor necrosis factor production [GO:0032760]; protein autophosphorylation [GO:0046777]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein localization to endoplasmic reticulum exit site [GO:0070973]; protein localization to mitochondrion [GO:0070585]; protein phosphorylation [GO:0006468]; reactive oxygen species metabolic process [GO:0072593]; regulation of autophagy [GO:0010506]; regulation of branching morphogenesis of a nerve [GO:2000172]; regulation of CAMKK-AMPK signaling cascade [GO:1905289]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of dopamine receptor signaling pathway [GO:0060159]; regulation of ER to Golgi vesicle-mediated transport [GO:0060628]; regulation of kidney size [GO:0035564]; regulation of locomotion [GO:0040012]; regulation of lysosomal lumen pH [GO:0035751]; regulation of membrane potential [GO:0042391]; regulation of mitochondrial depolarization [GO:0051900]; regulation of mitochondrial fission [GO:0090140]; regulation of neuroblast proliferation [GO:1902692]; regulation of neuron death [GO:1901214]; regulation of neuron maturation [GO:0014041]; regulation of protein kinase A signaling [GO:0010738]; regulation of protein stability [GO:0031647]; regulation of retrograde transport, endosome to Golgi [GO:1905279]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of synaptic vesicle exocytosis [GO:2000300]; regulation of synaptic vesicle transport [GO:1902803]; response to oxidative stress [GO:0006979]; signal transduction [GO:0007165]; spermatogenesis [GO:0007283]; striatum development [GO:0021756]; tangential migration from the subventricular zone to the olfactory bulb [GO:0022028]; Wnt signalosome assembly [GO:1904887] GO:0000139; GO:0000149; GO:0000165; GO:0000287; GO:0001933; GO:0001934; GO:0003779; GO:0003924; GO:0004672; GO:0004674; GO:0004706; GO:0004709; GO:0004722; GO:0005096; GO:0005524; GO:0005525; GO:0005615; GO:0005737; GO:0005739; GO:0005741; GO:0005743; GO:0005759; GO:0005764; GO:0005768; GO:0005783; GO:0005789; GO:0005794; GO:0005798; GO:0005802; GO:0005829; GO:0005886; GO:0005902; GO:0006468; GO:0006606; GO:0006897; GO:0006914; GO:0006979; GO:0007005; GO:0007029; GO:0007030; GO:0007040; GO:0007165; GO:0007254; GO:0007283; GO:0007528; GO:0008017; GO:0008104; GO:0008340; GO:0009267; GO:0010506; GO:0010508; GO:0010738; GO:0010955; GO:0010977; GO:0014041; GO:0015631; GO:0016234; GO:0016242; GO:0016301; GO:0016310; GO:0017075; GO:0018105; GO:0018107; GO:0019722; GO:0021756; GO:0021772; GO:0022028; GO:0030159; GO:0030276; GO:0030424; GO:0030425; GO:0030426; GO:0030672; GO:0031267; GO:0031398; GO:0031410; GO:0031647; GO:0031966; GO:0032091; GO:0032092; GO:0032436; GO:0032473; GO:0032760; GO:0032839; GO:0034211; GO:0034260; GO:0034599; GO:0035556; GO:0035564; GO:0035640; GO:0035641; GO:0035751; GO:0036479; GO:0039706; GO:0040012; GO:0042391; GO:0042802; GO:0042803; GO:0043005; GO:0043025; GO:0043068; GO:0043195; GO:0043204; GO:0043231; GO:0043406; GO:0044325; GO:0044753; GO:0044754; GO:0045121; GO:0045860; GO:0046039; GO:0046777; GO:0048312; GO:0048812; GO:0051018; GO:0051646; GO:0051770; GO:0051900; GO:0051966; GO:0060070; GO:0060079; GO:0060159; GO:0060161; GO:0060628; GO:0060828; GO:0061001; GO:0070062; GO:0070585; GO:0070971; GO:0070973; GO:0070997; GO:0071287; GO:0071407; GO:0072593; GO:0090140; GO:0090263; GO:0090394; GO:0097487; GO:0098794; GO:0098978; GO:0099400; GO:0099523; GO:0106310; GO:0140058; GO:1900244; GO:1901214; GO:1901215; GO:1901727; GO:1902236; GO:1902499; GO:1902692; GO:1902803; GO:1902823; GO:1902902; GO:1903125; GO:1903206; GO:1903215; GO:1903217; GO:1903351; GO:1903980; GO:1904713; GO:1904887; GO:1905279; GO:1905289; GO:1990904; GO:1990909; GO:2000172; GO:2000300 36739 XM_044307370.1 358 269 248 502 368 Q5S007 1.13e-52 Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin) Homo sapiens (Human) autophagy [GO:0006914]; calcium-mediated signaling [GO:0019722]; canonical Wnt signaling pathway [GO:0060070]; cellular response to dopamine [GO:1903351]; cellular response to manganese ion [GO:0071287]; cellular response to organic cyclic compound [GO:0071407]; cellular response to oxidative stress [GO:0034599]; cellular response to starvation [GO:0009267]; determination of adult lifespan [GO:0008340]; endocytosis [GO:0006897]; endoplasmic reticulum organization [GO:0007029]; excitatory postsynaptic potential [GO:0060079]; exploration behavior [GO:0035640]; Golgi organization [GO:0007030]; GTP metabolic process [GO:0046039]; intracellular distribution of mitochondria [GO:0048312]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; locomotory exploration behavior [GO:0035641]; lysosome organization [GO:0007040]; MAPK cascade [GO:0000165]; mitochondrion localization [GO:0051646]; mitochondrion organization [GO:0007005]; negative regulation of autophagosome assembly [GO:1902902]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of GTPase activity [GO:0034260]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of late endosome to lysosome transport [GO:1902823]; negative regulation of macroautophagy [GO:0016242]; negative regulation of neuron death [GO:1901215]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein binding [GO:0032091]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein processing [GO:0010955]; negative regulation of protein processing involved in protein targeting to mitochondrion [GO:1903217]; negative regulation of protein targeting to mitochondrion [GO:1903215]; negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation [GO:1903125]; neuromuscular junction development [GO:0007528]; neuron death [GO:0070997]; neuron projection arborization [GO:0140058]; neuron projection morphogenesis [GO:0048812]; olfactory bulb development [GO:0021772]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; phosphorylation [GO:0016310]; positive regulation of autophagy [GO:0010508]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of dopamine receptor signaling pathway [GO:0060161]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of programmed cell death [GO:0043068]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein autoubiquitination [GO:1902499]; positive regulation of protein binding [GO:0032092]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; positive regulation of tumor necrosis factor production [GO:0032760]; protein autophosphorylation [GO:0046777]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein localization to endoplasmic reticulum exit site [GO:0070973]; protein localization to mitochondrion [GO:0070585]; protein phosphorylation [GO:0006468]; reactive oxygen species metabolic process [GO:0072593]; regulation of autophagy [GO:0010506]; regulation of branching morphogenesis of a nerve [GO:2000172]; regulation of CAMKK-AMPK signaling cascade [GO:1905289]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of dopamine receptor signaling pathway [GO:0060159]; regulation of ER to Golgi vesicle-mediated transport [GO:0060628]; regulation of kidney size [GO:0035564]; regulation of locomotion [GO:0040012]; regulation of lysosomal lumen pH [GO:0035751]; regulation of membrane potential [GO:0042391]; regulation of mitochondrial depolarization [GO:0051900]; regulation of mitochondrial fission [GO:0090140]; regulation of neuroblast proliferation [GO:1902692]; regulation of neuron death [GO:1901214]; regulation of neuron maturation [GO:0014041]; regulation of protein kinase A signaling [GO:0010738]; regulation of protein stability [GO:0031647]; regulation of retrograde transport, endosome to Golgi [GO:1905279]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of synaptic vesicle exocytosis [GO:2000300]; regulation of synaptic vesicle transport [GO:1902803]; response to oxidative stress [GO:0006979]; signal transduction [GO:0007165]; spermatogenesis [GO:0007283]; striatum development [GO:0021756]; tangential migration from the subventricular zone to the olfactory bulb [GO:0022028]; Wnt signalosome assembly [GO:1904887] GO:0000139; GO:0000149; GO:0000165; GO:0000287; GO:0001933; GO:0001934; GO:0003779; GO:0003924; GO:0004672; GO:0004674; GO:0004706; GO:0004709; GO:0004722; GO:0005096; GO:0005524; GO:0005525; GO:0005615; GO:0005737; GO:0005739; GO:0005741; GO:0005743; GO:0005759; GO:0005764; GO:0005768; GO:0005783; GO:0005789; GO:0005794; GO:0005798; GO:0005802; GO:0005829; GO:0005886; GO:0005902; GO:0006468; GO:0006606; GO:0006897; GO:0006914; GO:0006979; GO:0007005; GO:0007029; GO:0007030; GO:0007040; GO:0007165; GO:0007254; GO:0007283; GO:0007528; GO:0008017; GO:0008104; GO:0008340; GO:0009267; GO:0010506; GO:0010508; GO:0010738; GO:0010955; GO:0010977; GO:0014041; GO:0015631; GO:0016234; GO:0016242; GO:0016301; GO:0016310; GO:0017075; GO:0018105; GO:0018107; GO:0019722; GO:0021756; GO:0021772; GO:0022028; GO:0030159; GO:0030276; GO:0030424; GO:0030425; GO:0030426; GO:0030672; GO:0031267; GO:0031398; GO:0031410; GO:0031647; GO:0031966; GO:0032091; GO:0032092; GO:0032436; GO:0032473; GO:0032760; GO:0032839; GO:0034211; GO:0034260; GO:0034599; GO:0035556; GO:0035564; GO:0035640; GO:0035641; GO:0035751; GO:0036479; GO:0039706; GO:0040012; GO:0042391; GO:0042802; GO:0042803; GO:0043005; GO:0043025; GO:0043068; GO:0043195; GO:0043204; GO:0043231; GO:0043406; GO:0044325; GO:0044753; GO:0044754; GO:0045121; GO:0045860; GO:0046039; GO:0046777; GO:0048312; GO:0048812; GO:0051018; GO:0051646; GO:0051770; GO:0051900; GO:0051966; GO:0060070; GO:0060079; GO:0060159; GO:0060161; GO:0060628; GO:0060828; GO:0061001; GO:0070062; GO:0070585; GO:0070971; GO:0070973; GO:0070997; GO:0071287; GO:0071407; GO:0072593; GO:0090140; GO:0090263; GO:0090394; GO:0097487; GO:0098794; GO:0098978; GO:0099400; GO:0099523; GO:0106310; GO:0140058; GO:1900244; GO:1901214; GO:1901215; GO:1901727; GO:1902236; GO:1902499; GO:1902692; GO:1902803; GO:1902823; GO:1902902; GO:1903125; GO:1903206; GO:1903215; GO:1903217; GO:1903351; GO:1903980; GO:1904713; GO:1904887; GO:1905279; GO:1905289; GO:1990904; GO:1990909; GO:2000172; GO:2000300 36740 XM_044317189.1 1092 3 605 1065 6 Q0VBU9 5.05e-39 Phospholipid phosphatase 4 (EC 3.1.3.4) (EC 3.6.1.75) Mus musculus (Mouse) blastocyst hatching [GO:0001835]; phospholipid dephosphorylation [GO:0046839]; phospholipid metabolic process [GO:0006644]; regulation of calcium ion import [GO:0090279] GO:0000810; GO:0001835; GO:0006644; GO:0008195; GO:0016020; GO:0042802; GO:0046839; GO:0090279 36741 XM_044309964.1 261 88 158 334 302 Q96AY4 1.83e-101 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36742 XM_044309964.1 261 88 158 334 302 Q96AY4 9.24e-100 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36743 XM_044309964.1 261 88 158 334 302 Q96AY4 2.04e-98 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36744 XM_044309964.1 261 88 158 334 302 Q96AY4 4.15e-96 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36745 XM_044309964.1 261 88 158 334 302 Q96AY4 1.86e-93 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36746 XM_044309964.1 261 88 158 334 302 Q96AY4 6.9e-58 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36747 XM_044309964.1 261 88 158 334 302 Q96AY4 1.44e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36748 XM_044309964.1 261 88 158 334 302 Q96AY4 3.59e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36749 XM_044322286.1 13 28 18 7 48 Q99570 3.23e-22 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 36750 XM_044314970.1 194 86 129 355 218 NA NA NA NA NA NA 36751 XR_003822745.2 1 18 12 22 20 NA NA NA NA NA NA 36752 XM_029345528.2 91 57 13 35 59 NA NA NA NA NA NA 36753 XM_029324289.2 13 14 21 23 25 Q7TN88 6.58e-59 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 36754 XM_029324289.2 13 14 21 23 25 Q7TN88 5.76e-41 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 36755 XM_044319856.1 137 32 23 204 116 P0CI65 1.69e-53 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 36756 XM_044319856.1 137 32 23 204 116 P0CI65 7.5e-45 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 36757 XM_044319856.1 137 32 23 204 116 P0CI65 6.53e-43 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 36758 XM_044319856.1 137 32 23 204 116 P0CI65 2.76e-35 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 36759 XM_029329965.2 1344 1090 678 1516 1606 NA NA NA NA NA NA 36760 XM_044310131.1 212 69 175 323 590 Q3UQ28 3.06e-32 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 36761 XM_044310131.1 212 69 175 323 590 Q3UQ28 1.06e-30 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 36762 XM_044308518.1 3 16 2 0 0 NA NA NA NA NA NA 36763 XM_029338644.2 0 0 0 10 0 P00767 2.8e-36 Chymotrypsinogen B (EC 3.4.21.1) [Cleaved into: Chymotrypsin B chain A; Chymotrypsin B chain B; Chymotrypsin B chain C] Bos taurus (Bovine) digestion [GO:0007586]; proteolysis [GO:0006508] GO:0004252; GO:0005615; GO:0006508; GO:0007586 36764 XM_044326258.1 7 1 0 6 9 Q96DM1 5.88e-30 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 36765 XM_029332236.2 5910 3852 2710 4647 4196 Q8K5C0 5.63e-79 Grainyhead-like protein 2 homolog (Brother of mammalian grainyhead) (Transcription factor CP2-like 3) Mus musculus (Mouse) anterior neural tube closure [GO:0061713]; bicellular tight junction assembly [GO:0070830]; brain development [GO:0007420]; camera-type eye development [GO:0043010]; cardiac ventricle morphogenesis [GO:0003208]; cell adhesion [GO:0007155]; cell junction assembly [GO:0034329]; cell population proliferation [GO:0008283]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digit morphogenesis [GO:0042733]; embryonic organ development [GO:0048568]; epidermis development [GO:0008544]; epithelial cell morphogenesis [GO:0003382]; epithelial cell morphogenesis involved in placental branching [GO:0060672]; epithelium migration [GO:0090132]; face development [GO:0060324]; in utero embryonic development [GO:0001701]; lung epithelial cell differentiation [GO:0060487]; lung lobe morphogenesis [GO:0060463]; multicellular organism growth [GO:0035264]; negative regulation of keratinocyte differentiation [GO:0045617]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of telomerase activity [GO:0051973]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA methylation [GO:0044030]; regulation of DNA-templated transcription [GO:0006355]; regulation of gene expression [GO:0010468]; regulation of transcription by RNA polymerase II [GO:0006357]; respiratory tube development [GO:0030323] GO:0000978; GO:0001161; GO:0001228; GO:0001701; GO:0001843; GO:0003208; GO:0003382; GO:0003677; GO:0003682; GO:0003700; GO:0005634; GO:0005654; GO:0005911; GO:0006355; GO:0006357; GO:0007155; GO:0007420; GO:0008283; GO:0008544; GO:0010468; GO:0016020; GO:0021915; GO:0030323; GO:0031490; GO:0034329; GO:0035264; GO:0042733; GO:0043010; GO:0043565; GO:0044030; GO:0045617; GO:0045893; GO:0045944; GO:0048568; GO:0048701; GO:0051973; GO:0060324; GO:0060463; GO:0060487; GO:0060672; GO:0061713; GO:0070830; GO:0090132 36766 XM_044326415.1 1426 283 130 1261 317 Q96DM1 6.74e-62 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 36767 XM_029338375.2 0 87 11 124 11 A6QR44 6.42e-60 Microprocessor complex subunit DGCR8 (DiGeorge syndrome critical region 8 homolog) Bos taurus (Bovine) primary miRNA processing [GO:0031053] GO:0003725; GO:0005730; GO:0020037; GO:0031053; GO:0042802; GO:0046872; GO:0070877; GO:0070878 36768 XR_006392877.1 41 2 25 5 151 NA NA NA NA NA NA 36769 XM_044309350.1 77 2 67 48 204 Q17QR8 2.76e-23 Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease) Bos taurus (Bovine) NA GO:0004518; GO:0005634; GO:0005829; GO:0005886; GO:0034451; GO:0046872 36770 XM_044319039.1 760 448 243 1280 755 Q6DD44 0 Xenotropic and polytropic retrovirus receptor 1 homolog Xenopus laevis (African clawed frog) cellular phosphate ion homeostasis [GO:0030643]; phosphate ion transmembrane transport [GO:0035435] GO:0000822; GO:0005886; GO:0015114; GO:0015562; GO:0030643; GO:0035435 36771 XM_029349673.2 39 27 13 17 53 NA NA NA NA NA NA 36772 XM_029326852.2 82 56 42 36 69 Q8BVT6 2.42e-34 Protein phosphatase 2C-like domain-containing protein 1 Mus musculus (Mouse) protein dephosphorylation [GO:0006470] GO:0004722; GO:0006470 36773 XM_044316105.1 107 42 36 35 28 NA NA NA NA NA NA 36774 XM_044328119.1 592 472 392 630 483 A7SKE9 2.66e-142 Eukaryotic translation initiation factor 3 subunit G (eIF3g) (Eukaryotic translation initiation factor 3 RNA-binding subunit) (eIF-3 RNA-binding subunit) (Eukaryotic translation initiation factor 3 subunit 4) Nematostella vectensis (Starlet sea anemone) formation of cytoplasmic translation initiation complex [GO:0001732] GO:0001732; GO:0003723; GO:0003743; GO:0005852; GO:0016282; GO:0033290 36775 XM_044328592.1 0 0 14 21 5 NA NA NA NA NA NA 36776 XM_044324545.1 0 58 0 236 13 H1AFJ5 2.4e-39 Amiloride-sensitive sodium channel subunit alpha (Alpha-NaCH) (Epithelial Na(+) channel subunit alpha) (Alpha-ENaC) (Nonvoltage-gated sodium channel 1 subunit alpha) (SCNEA) Neoceratodus forsteri (Australian lungfish) (Ceratodus forsteri) sodium ion transmembrane transport [GO:0035725] GO:0001669; GO:0005737; GO:0015280; GO:0016324; GO:0031514; GO:0034706; GO:0035725 36777 XM_029341347.2 564 761 398 759 827 Q91WD2 1.79e-39 Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Calcium transport protein 1) (CaT1) (Epithelial calcium channel 2) (ECaC2) Mus musculus (Mouse) calcium ion homeostasis [GO:0055074]; calcium ion import [GO:0070509]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; parathyroid hormone secretion [GO:0035898]; protein homotetramerization [GO:0051289]; response to calcium ion [GO:0051592] GO:0005216; GO:0005262; GO:0005516; GO:0005886; GO:0006816; GO:0016020; GO:0034704; GO:0035898; GO:0042802; GO:0046872; GO:0051289; GO:0051592; GO:0055074; GO:0070509; GO:0070588; GO:0098703 36778 XM_044306847.1 554 258 362 214 298 Q8CCP0 0 Ribosome quality control complex subunit NEMF (Nuclear export mediator factor) (Serologically defined colon cancer antigen 1 homolog) Mus musculus (Mouse) CAT tailing [GO:0140708]; nuclear export [GO:0051168]; protein-containing complex assembly [GO:0065003]; rescue of stalled ribosome [GO:0072344]; ribosome-associated ubiquitin-dependent protein catabolic process [GO:1990116] GO:0000049; GO:0005634; GO:0005829; GO:0043023; GO:0051168; GO:0065003; GO:0072344; GO:0140708; GO:1990112; GO:1990116 36779 XM_044306847.1 554 258 362 214 298 Q8CCP0 4.05e-33 Ribosome quality control complex subunit NEMF (Nuclear export mediator factor) (Serologically defined colon cancer antigen 1 homolog) Mus musculus (Mouse) CAT tailing [GO:0140708]; nuclear export [GO:0051168]; protein-containing complex assembly [GO:0065003]; rescue of stalled ribosome [GO:0072344]; ribosome-associated ubiquitin-dependent protein catabolic process [GO:1990116] GO:0000049; GO:0005634; GO:0005829; GO:0043023; GO:0051168; GO:0065003; GO:0072344; GO:0140708; GO:1990112; GO:1990116 36780 XR_003827261.2 388 315 196 1568 869 NA NA NA NA NA NA 36781 XR_006397110.1 379 305 302 166 361 NA NA NA NA NA NA 36782 XM_029335103.2 2205 2944 2249 1915 821 NA NA NA NA NA NA 36783 XM_044309121.1 13 0 0 0 0 NA NA NA NA NA NA 36784 XM_029353077.2 54 72 25 103 44 D2CLZ9 1.58e-22 Transcription factor atoh8 (Atonal bHLH transcription factor 8) (Protein atonal homolog 8) Danio rerio (Zebrafish) (Brachydanio rerio) heart development [GO:0007507]; heart looping [GO:0001947]; neuron differentiation [GO:0030182]; regulation of neural retina development [GO:0061074]; regulation of skeletal muscle cell differentiation [GO:2001014]; regulation of transcription by RNA polymerase II [GO:0006357]; swim bladder formation [GO:0048797] GO:0000978; GO:0000981; GO:0001947; GO:0005634; GO:0005737; GO:0006357; GO:0007507; GO:0016607; GO:0030182; GO:0046983; GO:0048797; GO:0061074; GO:2001014 36785 XM_029356441.2 0 6 9 0 13 NA NA NA NA NA NA 36786 XM_044319817.1 63 35 49 55 129 P97288 5.63e-36 5-hydroxytryptamine receptor 4 (5-HT-4) (5-HT4) (Serotonin receptor 4) Mus musculus (Mouse) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting serotonin receptor signaling pathway [GO:0007198]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; gamma-aminobutyric acid signaling pathway [GO:0007214]; regulation of appetite [GO:0032098] GO:0004993; GO:0005737; GO:0005768; GO:0005886; GO:0007187; GO:0007189; GO:0007198; GO:0007214; GO:0007268; GO:0016020; GO:0030425; GO:0030594; GO:0032098; GO:0045202; GO:0051378 36787 XM_044313216.1 692 244 115 91 708 P54315 1.68e-65 Inactive pancreatic lipase-related protein 1 (PL-RP1) Homo sapiens (Human) lipid metabolic process [GO:0006629] GO:0004806; GO:0005509; GO:0005576; GO:0006629 36788 XM_029339137.2 2023 2142 1079 1507 1120 NA NA NA NA NA NA 36789 XM_044312408.1 1 1 0 9 1 NA NA NA NA NA NA 36790 XM_029346531.2 67 81 0 13 0 Q9I8C7 8.61e-93 Neuronal acetylcholine receptor subunit alpha-10 (Alpha 10 nAChR) (Nicotinic acetylcholine receptor subunit alpha-10) (NACHR alpha-10) Gallus gallus (Chicken) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; response to auditory stimulus [GO:0010996]; signal transduction [GO:0007165] GO:0004888; GO:0005231; GO:0005262; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0010996; GO:0022848; GO:0030594; GO:0034220; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051899; GO:1904315 36791 XR_003822988.2 100 146 52 78 104 NA NA NA NA NA NA 36792 XM_029347400.2 214 47 186 65 63 O13267 5.76e-91 Protein Wnt-5a (PWnt-5a) Pleurodeles waltl (Iberian ribbed newt) anatomical structure development [GO:0048856]; Wnt signaling pathway [GO:0016055] GO:0005102; GO:0005576; GO:0016055; GO:0048856 36793 XM_044313180.1 47 38 43 34 86 NA NA NA NA NA NA 36794 XR_006393407.1 0 0 0 0 12 NA NA NA NA NA NA 36795 XM_044322933.1 650 221 512 270 1662 NA NA NA NA NA NA 36796 XM_044321939.1 16 136 205 0 10 NA NA NA NA NA NA 36797 XM_044325596.1 0 0 1 16 0 NA NA NA NA NA NA 36798 XM_029340149.2 10 0 6 0 22 NA NA NA NA NA NA 36799 XM_029326074.1 632 410 332 568 555 Q9UHR5 2.73e-27 SAP30-binding protein (Transcriptional regulator protein HCNGP) Homo sapiens (Human) modulation by host of symbiont transcription [GO:0052472]; positive regulation of histone deacetylation [GO:0031065]; regulation of DNA-templated transcription [GO:0006355]; response to virus [GO:0009615] GO:0005634; GO:0005654; GO:0006355; GO:0009615; GO:0031065; GO:0045111; GO:0052472 36800 XM_044314986.1 111 69 43 131 153 A8DYE2 2.65e-26 Transient receptor potential cation channel trpm (Transient receptor potential cation channel, subfamily M ortholog) Drosophila melanogaster (Fruit fly) cation transmembrane transport [GO:0098655]; cellular zinc ion homeostasis [GO:0006882]; magnesium ion homeostasis [GO:0010960]; metal ion transport [GO:0030001]; protein tetramerization [GO:0051262] GO:0005261; GO:0005385; GO:0005886; GO:0006882; GO:0010960; GO:0022890; GO:0030001; GO:0034703; GO:0051262; GO:0097682; GO:0098655 36801 XM_044314529.1 14 0 3 0 33 NA NA NA NA NA NA 36802 XM_044326185.1 11 34 12 7 38 NA NA NA NA NA NA 36803 XM_044321193.1 0 0 0 0 8 Q8SX37 3.2e-21 CDP-diacylglycerol--inositol 3-phosphatidyltransferase (CDIPT) (EC 2.7.8.11) (Phosphatidylinositol synthase) Drosophila melanogaster (Fruit fly) basement membrane organization [GO:0071711]; phosphatidylinositol biosynthetic process [GO:0006661]; phototransduction [GO:0007602] GO:0003881; GO:0005794; GO:0006661; GO:0007602; GO:0016324; GO:0016328; GO:0046872; GO:0071711 36804 XM_029358667.2 84 137 174 277 149 NA NA NA NA NA NA 36805 XM_029331769.2 663 387 321 590 668 Q9R1A8 0 E3 ubiquitin-protein ligase COP1 (EC 2.3.2.27) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1) (RING finger and WD repeat domain protein 2) (RING-type E3 ubiquitin transferase RFWD2) Mus musculus (Mouse) positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; response to ionizing radiation [GO:0010212] GO:0000139; GO:0010212; GO:0016607; GO:0031464; GO:0032436; GO:0043161; GO:0046872; GO:0061630 36806 XM_044323449.1 27 12 34 54 13 Q7RTR2 2.47e-40 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 36807 XM_029333455.2 17 35 160 2406 518 A2RRH5 4.88e-101 WD repeat-containing protein 27 Homo sapiens (Human) NA GO:0005654 36808 XM_029335668.2 106 89 0 559 294 F1MA98 0 Nucleoprotein TPR (Megator) (NPC-associated intranuclear protein) (Translocated promoter region protein) Rattus norvegicus (Rat) cell division [GO:0051301]; cellular response to heat [GO:0034605]; cellular response to interferon-alpha [GO:0035457]; mitotic spindle assembly checkpoint signaling [GO:0007094]; mRNA export from nucleus [GO:0006406]; mRNA export from nucleus in response to heat stress [GO:0031990]; negative regulation of RNA export from nucleus [GO:0046832]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of translational initiation [GO:0045947]; nuclear pore organization [GO:0006999]; positive regulation of heterochromatin formation [GO:0031453]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; regulation of mitotic sister chromatid separation [GO:0010965]; regulation of mitotic spindle assembly [GO:1901673]; regulation of protein localization [GO:0032880]; response to epidermal growth factor [GO:0070849]; RNA export from nucleus [GO:0006405]; RNA import into nucleus [GO:0006404] GO:0000122; GO:0000776; GO:0003682; GO:0003729; GO:0005634; GO:0005635; GO:0005643; GO:0005737; GO:0005868; GO:0006404; GO:0006405; GO:0006406; GO:0006606; GO:0006611; GO:0006999; GO:0007094; GO:0010965; GO:0015631; GO:0017056; GO:0019898; GO:0031072; GO:0031453; GO:0031965; GO:0031990; GO:0032880; GO:0034399; GO:0034605; GO:0035457; GO:0042307; GO:0042405; GO:0042803; GO:0044615; GO:0045947; GO:0046827; GO:0046832; GO:0051019; GO:0051301; GO:0070840; GO:0070849; GO:0072686; GO:0090267; GO:0090316; GO:1901673 36809 XM_029350410.2 1 4 9 3 0 E7FAM5 1e-78 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 36810 XM_029331635.2 698 531 142 1010 281 Q8BZ20 6.46e-55 Protein mono-ADP-ribosyltransferase PARP12 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 12) (ARTD12) (Poly [ADP-ribose] polymerase 12) (PARP-12) (Zinc finger CCCH domain-containing protein 1) Mus musculus (Mouse) protein auto-ADP-ribosylation [GO:0070213] GO:0003950; GO:0005634; GO:0016779; GO:0046872; GO:0070213; GO:0140803; GO:1990404 36811 XM_044325001.1 3 3 9 6 0 NA NA NA NA NA NA 36812 XM_029347112.2 219 136 98 121 242 NA NA NA NA NA NA 36813 XM_044317770.1 470 516 312 806 747 P67999 0 Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA) Rattus norvegicus (Rat) aging [GO:0007568]; apoptotic process [GO:0006915]; behavioral fear response [GO:0001662]; cell migration [GO:0016477]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to growth factor stimulus [GO:0071363]; cellular response to hormone stimulus [GO:0032870]; cellular response to insulin stimulus [GO:0032869]; cellular response to organic cyclic compound [GO:0071407]; cellular response to type II interferon [GO:0071346]; G1/S transition of mitotic cell cycle [GO:0000082]; germ cell development [GO:0007281]; long-chain fatty acid import into cell [GO:0044539]; long-term memory [GO:0007616]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of insulin receptor signaling pathway [GO:0046627]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of skeletal muscle tissue growth [GO:0048633]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of translation [GO:0045727]; positive regulation of translational initiation [GO:0045948]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; regulation of glucose import [GO:0046324]; response to amino acid [GO:0043200]; response to electrical stimulus involved in regulation of muscle adaptation [GO:0014878]; response to ethanol [GO:0045471]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to insulin [GO:0032868]; response to leucine [GO:0043201]; response to lipopolysaccharide [GO:0032496]; response to mechanical stimulus [GO:0009612]; response to nutrient [GO:0007584]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to testosterone [GO:0033574]; response to toxic substance [GO:0009636]; response to tumor necrosis factor [GO:0034612]; response to wounding [GO:0009611]; response to xenobiotic stimulus [GO:0009410]; skeletal muscle atrophy [GO:0014732]; skeletal muscle contraction [GO:0003009]; TOR signaling [GO:0031929] GO:0000082; GO:0001662; GO:0003009; GO:0004672; GO:0004674; GO:0004711; GO:0004712; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005741; GO:0005829; GO:0006468; GO:0006915; GO:0007281; GO:0007568; GO:0007584; GO:0007616; GO:0009408; GO:0009410; GO:0009611; GO:0009612; GO:0009636; GO:0009749; GO:0009986; GO:0010033; GO:0010243; GO:0014070; GO:0014732; GO:0014878; GO:0014911; GO:0016477; GO:0018105; GO:0030165; GO:0031667; GO:0031929; GO:0032496; GO:0032868; GO:0032869; GO:0032870; GO:0033574; GO:0033762; GO:0034612; GO:0042277; GO:0042802; GO:0043005; GO:0043066; GO:0043200; GO:0043201; GO:0043434; GO:0043491; GO:0044539; GO:0045202; GO:0045471; GO:0045727; GO:0045931; GO:0045948; GO:0046324; GO:0046627; GO:0048471; GO:0048633; GO:0048661; GO:0050804; GO:0051384; GO:0051721; GO:0071346; GO:0071363; GO:0071407; GO:0071549; GO:0098794; GO:0098978; GO:0106310; GO:2001237 36814 XM_029331288.2 3231 3582 1959 3979 1734 Q5ZID0 3.11e-73 NmrA-like family domain-containing protein 1 Gallus gallus (Chicken) NA GO:0005634; GO:0048471 36815 XM_044316596.1 0 463 37 0 0 Q8BWC0 9.34e-160 Two pore channel protein 2 (Two pore calcium channel protein 2) (Voltage-dependent calcium channel protein TPC2) Mus musculus (Mouse) calcium-mediated signaling [GO:0019722]; cellular calcium ion homeostasis [GO:0006874]; endocytosis involved in viral entry into host cell [GO:0075509]; endosome to lysosome transport of low-density lipoprotein particle [GO:0090117]; intracellular pH reduction [GO:0051452]; lysosome organization [GO:0007040]; negative regulation of developmental pigmentation [GO:0048086]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of autophagy [GO:0010506]; regulation of exocytosis [GO:0017157]; regulation of ion transmembrane transport [GO:0034765]; release of sequestered calcium ion into cytosol [GO:0051209]; response to vitamin D [GO:0033280]; smooth muscle contraction [GO:0006939]; sodium ion transmembrane transport [GO:0035725] GO:0005245; GO:0005262; GO:0005764; GO:0005765; GO:0005829; GO:0006874; GO:0006939; GO:0007040; GO:0010008; GO:0010506; GO:0015280; GO:0017157; GO:0019065; GO:0019722; GO:0019901; GO:0031902; GO:0033162; GO:0033280; GO:0034765; GO:0035725; GO:0036020; GO:0042802; GO:0048086; GO:0051209; GO:0051452; GO:0072345; GO:0075509; GO:0080025; GO:0090117; GO:0097682 36816 XR_006393942.1 155 59 80 244 82 Q17QR8 7.04e-29 Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease) Bos taurus (Bovine) NA GO:0004518; GO:0005634; GO:0005829; GO:0005886; GO:0034451; GO:0046872 36817 XM_029328078.2 222 450 145 330 195 Q6DRI7 8.67e-154 ATP-dependent RNA helicase DDX51 (EC 3.6.4.13) (DEAD box protein 51) Danio rerio (Zebrafish) (Brachydanio rerio) rRNA processing [GO:0006364] GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005730; GO:0006364; GO:0016887 36818 XM_044311525.1 100 0 8 55 63 Q9VBW3 4.85e-78 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 36819 XM_044318996.1 661 906 446 837 753 O93257 1.71e-176 X-ray repair cross-complementing protein 5 (EC 3.6.4.-) (EC 4.2.99.-) (5'-deoxyribose-5-phosphate lyase Ku70) (5'-dRP/AP lyase Ku70) (ATP-dependent DNA helicase 2 subunit 1) (ATP-dependent DNA helicase II 70 kDa subunit) (DNA repair protein XRCC6) (Ku autoantigen protein p70 homolog) (Ku70) Gallus gallus (Chicken) cellular response to gamma radiation [GO:0071480]; cellular response to X-ray [GO:0071481]; DNA recombination [GO:0006310]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of DNA-templated transcription [GO:0045892]; telomere maintenance [GO:0000723] GO:0000723; GO:0003678; GO:0003684; GO:0003723; GO:0005524; GO:0005654; GO:0005694; GO:0006303; GO:0006310; GO:0016787; GO:0042162; GO:0043564; GO:0045892; GO:0051575; GO:0070419; GO:0071480; GO:0071481; GO:1990904 36820 XM_044309205.1 70 32 40 27 103 P81274 1.97e-24 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 36821 XM_044310184.1 62 27 125 615 509 Q9NZJ4 0 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 36822 XM_029347159.2 1244 1005 819 1421 982 Q99PT9 0 Kinesin-like protein KIF19 Mus musculus (Mouse) axonemal microtubule depolymerization [GO:0060404]; microtubule-based movement [GO:0007018]; plus-end specific microtubule depolymerization [GO:0070462] GO:0003777; GO:0005524; GO:0005871; GO:0005874; GO:0005929; GO:0005930; GO:0007018; GO:0008017; GO:0008574; GO:0016887; GO:0060404; GO:0070462 36823 XM_029344240.2 383 140 378 206 47 Q9DC70 4.72e-98 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (EC 7.1.1.2) (Complex I-20kD) (CI-20kD) (NADH-ubiquinone oxidoreductase 20 kDa subunit) Mus musculus (Mouse) aerobic respiration [GO:0009060]; electron transport coupled proton transport [GO:0015990]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrial respiratory chain complex I assembly [GO:0032981]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776] GO:0002020; GO:0003954; GO:0005739; GO:0005743; GO:0005747; GO:0006120; GO:0008137; GO:0009060; GO:0015990; GO:0032981; GO:0042776; GO:0043005; GO:0043025; GO:0046872; GO:0048038; GO:0051539; GO:0097060 36824 XM_029340970.2 0 26 0 0 152 NA NA NA NA NA NA 36825 XM_044326697.1 173 76 1 1 159 NA NA NA NA NA NA 36826 XM_029356339.2 0 0 0 0 77 P0CF65 6.89e-98 Protein cereblon Gallus gallus (Chicken) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567] GO:0005634; GO:0005737; GO:0016567; GO:0031464; GO:0043161; GO:0046872 36827 XM_044322332.1 52 21 7 19 12 Q0V7M0 0 Importin subunit alpha-7 (Karyopherin subunit alpha-6) Bos taurus (Bovine) NLS-bearing protein import into nucleus [GO:0006607] GO:0005634; GO:0005654; GO:0005737; GO:0006607; GO:0008139; GO:0061608 36828 XM_044309521.1 181 150 43 155 140 NA NA NA NA NA NA 36829 XM_029353299.2 52 69 25 131 85 NA NA NA NA NA NA 36830 XM_029329150.2 2458 1736 1578 2161 1996 Q12802 2.79e-82 A-kinase anchor protein 13 (AKAP-13) (AKAP-Lbc) (Breast cancer nuclear receptor-binding auxiliary protein) (Guanine nucleotide exchange factor Lbc) (Human thyroid-anchoring protein 31) (Lymphoid blast crisis oncogene) (LBC oncogene) (Non-oncogenic Rho GTPase-specific GTP exchange factor) (Protein kinase A-anchoring protein 13) (PRKA13) (p47) Homo sapiens (Human) adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process [GO:0086023]; adrenergic receptor signaling pathway [GO:0071875]; bone development [GO:0060348]; cardiac muscle cell differentiation [GO:0055007]; cell growth involved in cardiac muscle cell development [GO:0061049]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; nuclear export [GO:0051168]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Rho protein signal transduction [GO:0035025]; regulation of Rho protein signal transduction [GO:0035023]; regulation of sarcomere organization [GO:0060297]; regulation of small GTPase mediated signal transduction [GO:0051056] GO:0005078; GO:0005085; GO:0005634; GO:0005829; GO:0005938; GO:0007186; GO:0007507; GO:0016020; GO:0031267; GO:0035023; GO:0035025; GO:0043123; GO:0043406; GO:0046872; GO:0048471; GO:0051018; GO:0051056; GO:0051168; GO:0055007; GO:0060090; GO:0060297; GO:0060348; GO:0061049; GO:0071875; GO:0086023 36831 XM_044318714.1 0 0 0 5 8 Q7LGC8 2.05e-28 Carbohydrate sulfotransferase 3 (EC 2.8.2.17) (EC 2.8.2.21) (Chondroitin 6-O-sulfotransferase 1) (C6ST-1) (Chondroitin 6-sulfotransferase) (C6ST) (Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 0) (GST-0) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; chondroitin sulfate biosynthetic process [GO:0030206]; N-acetylglucosamine metabolic process [GO:0006044]; sulfur compound metabolic process [GO:0006790]; T cell homeostasis [GO:0043029] GO:0000139; GO:0001517; GO:0005802; GO:0005975; GO:0006044; GO:0006790; GO:0008459; GO:0030206; GO:0043029; GO:0050698 36832 XM_044321121.1 6 4 0 1 0 NA NA NA NA NA NA 36833 XM_029355751.2 192 150 0 77 429 R1CW23 8.54e-91 Dimethylsulfonioproprionate lyase 7 (DMSP lyase 7) (EC 4.4.1.3) (Dimethylpropiothetin dethiomethylase 7) Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi) NA GO:0047869 36834 XM_044329272.1 823 413 348 979 900 P49756 1.81e-53 RNA-binding protein 25 (Arg/Glu/Asp-rich protein of 120 kDa) (RED120) (Protein S164) (RNA-binding motif protein 25) (RNA-binding region-containing protein 7) Homo sapiens (Human) mRNA processing [GO:0006397]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of apoptotic process [GO:0042981]; RNA splicing [GO:0008380] GO:0000381; GO:0003723; GO:0003729; GO:0005737; GO:0006397; GO:0008380; GO:0016607; GO:0042981 36835 XM_044329272.1 823 413 348 979 900 P49756 4.46e-33 RNA-binding protein 25 (Arg/Glu/Asp-rich protein of 120 kDa) (RED120) (Protein S164) (RNA-binding motif protein 25) (RNA-binding region-containing protein 7) Homo sapiens (Human) mRNA processing [GO:0006397]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of apoptotic process [GO:0042981]; RNA splicing [GO:0008380] GO:0000381; GO:0003723; GO:0003729; GO:0005737; GO:0006397; GO:0008380; GO:0016607; GO:0042981 36836 XM_044315155.1 0 0 282 0 0 NA NA NA NA NA NA 36837 XM_029335071.2 107 102 123 118 175 P10079 5.92e-72 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36838 XM_029335071.2 107 102 123 118 175 P10079 4.93e-68 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36839 XM_029335071.2 107 102 123 118 175 P10079 5.73e-66 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36840 XM_029335071.2 107 102 123 118 175 P10079 2.83e-63 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36841 XM_029335071.2 107 102 123 118 175 P10079 4.22e-47 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36842 XM_029335071.2 107 102 123 118 175 P10079 9.75e-42 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36843 XM_029335071.2 107 102 123 118 175 P10079 2.44e-25 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36844 XR_006395203.1 0 3 0 6 0 NA NA NA NA NA NA 36845 XM_029334456.2 1220 742 1220 1065 265 Q26636 2.71e-124 Cathepsin L (EC 3.4.22.15) [Cleaved into: Cathepsin L heavy chain; Cathepsin L light chain] Sarcophaga peregrina (Flesh fly) (Boettcherisca peregrina) cell differentiation [GO:0030154]; proteolysis [GO:0006508] GO:0004197; GO:0005764; GO:0006508; GO:0030154 36846 XM_044329023.1 982 339 35 1029 710 Q9Y2G1 2.06e-131 Myelin regulatory factor (EC 3.4.-.-) (Myelin gene regulatory factor) [Cleaved into: Myelin regulatory factor, N-terminal; Myelin regulatory factor, C-terminal] Homo sapiens (Human) central nervous system myelin maintenance [GO:0032286]; central nervous system myelination [GO:0022010]; oligodendrocyte development [GO:0014003]; oligodendrocyte differentiation [GO:0048709]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of myelination [GO:0031643]; protein autoprocessing [GO:0016540] GO:0000981; GO:0003677; GO:0003700; GO:0005634; GO:0005654; GO:0005789; GO:0005794; GO:0005829; GO:0008233; GO:0014003; GO:0016540; GO:0022010; GO:0031643; GO:0032286; GO:0042802; GO:0043565; GO:0045893; GO:0048709 36847 XM_029347473.2 135 439 137 338 120 NA NA NA NA NA NA 36848 XM_029336480.2 24547 38113 15437 23604 16347 P24049 2.32e-89 60S ribosomal protein L17 (Amino acid starvation-induced protein) (ASI) (L23) Rattus norvegicus (Rat) cellular response to amino acid starvation [GO:0034198]; cytoplasmic translation [GO:0002181]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; response to amino acid starvation [GO:1990928] GO:0002181; GO:0003735; GO:0005634; GO:0005844; GO:0022625; GO:0022626; GO:0031672; GO:0034198; GO:0045202; GO:0070180; GO:1900087; GO:1990928 36849 XM_044307184.1 24 0 15 8 23 Q9MYM7 2.98e-29 Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.86) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1) Pongo pygmaeus (Bornean orangutan) lipid metabolic process [GO:0006629]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0006629; GO:0047275 36850 XM_029339177.2 80 202 96 125 56 NA NA NA NA NA NA 36851 XM_029327280.2 72 54 75 131 106 Q6NZ04 1.8e-75 Homeobox protein six1b (Homeobox protein six1a) (Sine oculis homeobox homolog 1a) (Sine oculis homeobox homolog 1b) Danio rerio (Zebrafish) (Brachydanio rerio) adenohypophysis development [GO:0021984]; apoptotic process [GO:0006915]; extraocular skeletal muscle development [GO:0002074]; inner ear development [GO:0048839]; peripheral nervous system neuron development [GO:0048935]; pharyngeal muscle development [GO:0043282]; regulation of skeletal muscle cell proliferation [GO:0014857]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal muscle fiber development [GO:0048741]; striated muscle cell differentiation [GO:0051146] GO:0000978; GO:0000981; GO:0002074; GO:0005634; GO:0005667; GO:0005737; GO:0006357; GO:0006915; GO:0014857; GO:0021984; GO:0043282; GO:0048741; GO:0048839; GO:0048935; GO:0051146 36852 XR_006396774.1 51 444 732 274 193 NA NA NA NA NA NA 36853 XM_044322750.1 55 668 1151 982 1247 Q9NZJ4 0 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 36854 XM_044322750.1 55 668 1151 982 1247 Q9NZJ4 2.69e-52 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 36855 XM_044322750.1 55 668 1151 982 1247 Q9NZJ4 6.62e-40 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 36856 XM_044322163.1 1561 1298 1071 1020 807 O22943 3.25e-91 Probable glycosyltransferase STELLO1 (EC 2.4.-.-) Arabidopsis thaliana (Mouse-ear cress) plant-type cell wall cellulose biosynthetic process [GO:0052324]; regulation of plant-type cell wall cellulose biosynthetic process [GO:2001009] GO:0000139; GO:0005768; GO:0005794; GO:0005802; GO:0016757; GO:0042802; GO:0052324; GO:2001009 36857 XM_029341612.2 777 852 345 918 1024 Q80XS6 9.46e-75 Protein Smaug homolog 2 (Smaug 2) (mSmaug2) (Sterile alpha motif domain-containing protein 4B) Mus musculus (Mouse) cerebellar neuron development [GO:0098749]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289] GO:0000289; GO:0000932; GO:0003729; GO:0005634; GO:0005829; GO:0030371; GO:0098749 36858 XR_006396203.1 87 49 50 71 76 NA NA NA NA NA NA 36859 XM_029331408.2 124 0 224 259 77 Q5BKF8 9.65e-57 Cyclin-L2 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) regulation of transcription by RNA polymerase II [GO:0006357] GO:0006357; GO:0016538; GO:0016607 36860 XM_029354162.2 227 207 106 241 113 G3M4F8 1.33e-40 Octopamine receptor beta-2R (CsOA2B2) Chilo suppressalis (Asiatic rice borer moth) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cellular response to amine stimulus [GO:0071418]; octopamine signaling pathway [GO:0071927]; tyramine signaling pathway [GO:0071928] GO:0004989; GO:0005886; GO:0007189; GO:0008226; GO:0016020; GO:0071418; GO:0071927; GO:0071928 36861 XM_044319702.1 101 23 22 94 58 E7FAM5 1.52e-79 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 36862 XM_029324487.2 75 42 28 39 47 NA NA NA NA NA NA 36863 XM_044307508.1 3 15 0 0 5 NA NA NA NA NA NA 36864 XM_029352781.2 959 597 406 692 554 NA NA NA NA NA NA 36865 XM_029347155.2 209 62 319 0 0 O88427 0 Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage-gated calcium channel subunit alpha Cav3.2) Mus musculus (Mouse) aldosterone biosynthetic process [GO:0032342]; calcium ion import [GO:0070509]; calcium ion transport [GO:0006816]; cortisol biosynthetic process [GO:0034651]; inorganic cation transmembrane transport [GO:0098662]; membrane depolarization during action potential [GO:0086010]; neuronal action potential [GO:0019228]; positive regulation of acrosome reaction [GO:2000344]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of cardiac muscle cell contraction [GO:0106134]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; sensory perception of pain [GO:0019233] GO:0001518; GO:0005244; GO:0005248; GO:0005634; GO:0005737; GO:0005886; GO:0005891; GO:0005901; GO:0006816; GO:0008332; GO:0016020; GO:0019228; GO:0019233; GO:0030425; GO:0032342; GO:0034651; GO:0034765; GO:0042383; GO:0042391; GO:0043005; GO:0043204; GO:0045211; GO:0045956; GO:0046872; GO:0048787; GO:0070509; GO:0086010; GO:0097110; GO:0098662; GO:0098978; GO:0106134; GO:2000344 36866 XM_029347155.2 209 62 319 0 0 O88427 2.51e-88 Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage-gated calcium channel subunit alpha Cav3.2) Mus musculus (Mouse) aldosterone biosynthetic process [GO:0032342]; calcium ion import [GO:0070509]; calcium ion transport [GO:0006816]; cortisol biosynthetic process [GO:0034651]; inorganic cation transmembrane transport [GO:0098662]; membrane depolarization during action potential [GO:0086010]; neuronal action potential [GO:0019228]; positive regulation of acrosome reaction [GO:2000344]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of cardiac muscle cell contraction [GO:0106134]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; sensory perception of pain [GO:0019233] GO:0001518; GO:0005244; GO:0005248; GO:0005634; GO:0005737; GO:0005886; GO:0005891; GO:0005901; GO:0006816; GO:0008332; GO:0016020; GO:0019228; GO:0019233; GO:0030425; GO:0032342; GO:0034651; GO:0034765; GO:0042383; GO:0042391; GO:0043005; GO:0043204; GO:0045211; GO:0045956; GO:0046872; GO:0048787; GO:0070509; GO:0086010; GO:0097110; GO:0098662; GO:0098978; GO:0106134; GO:2000344 36867 XR_006391367.1 579 326 358 473 420 Q6DBY9 1.94e-29 Carbohydrate sulfotransferase 1 (EC 2.8.2.21) (Keratan sulfate Gal-6 sulfotransferase) (KS6ST) (KSGal6ST) (KSST) Danio rerio (Zebrafish) (Brachydanio rerio) carbohydrate metabolic process [GO:0005975]; keratan sulfate metabolic process [GO:0042339]; N-acetylglucosamine metabolic process [GO:0006044]; sulfur compound metabolic process [GO:0006790] GO:0000139; GO:0001517; GO:0005802; GO:0005975; GO:0006044; GO:0006790; GO:0042339; GO:0045130 36868 XM_029337807.2 17646 7335 10187 3360 3888 NA NA NA NA NA NA 36869 XM_044313523.1 30 9 34 47 64 A0A0C2SRU0 9.13e-80 Decarboxylase iboD (EC 4.1.1.-) (Ibotenic acid biosynthesis cluster protein D) Amanita muscaria (strain Koide BX008) phospholipid biosynthetic process [GO:0008654] GO:0004609; GO:0008654 36870 XM_044307896.1 916 0 201 84 30 Q6DIP8 8.94e-96 Cotranscriptional regulator FAM172A homolog (Protein FAM172A) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0005634; GO:0005737; GO:0006397; GO:0008380 36871 XM_029342084.2 11 9 10 9 2 NA NA NA NA NA NA 36872 XR_006397854.1 17 13 26 23 21 NA NA NA NA NA NA 36873 XM_044315917.1 0 3 9 0 6 NA NA NA NA NA NA 36874 XR_003828554.2 87 26 42 57 73 NA NA NA NA NA NA 36875 XM_029326889.2 1618 1663 960 1269 879 P61087 6.59e-90 Ubiquitin-conjugating enzyme E2 K (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme K) (Huntingtin-interacting protein 2) (HIP-2) (Ubiquitin carrier protein) (Ubiquitin-conjugating enzyme E2-25 kDa) (Ubiquitin-conjugating enzyme E2(25K)) (Ubiquitin-conjugating enzyme E2-25K) (Ubiquitin-protein ligase) Mus musculus (Mouse) cellular response to interferon-beta [GO:0035458]; free ubiquitin chain polymerization [GO:0010994]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434] GO:0000209; GO:0004842; GO:0005524; GO:0005634; GO:0005737; GO:0010800; GO:0010994; GO:0031625; GO:0032433; GO:0032434; GO:0034450; GO:0035458; GO:0043161; GO:0060340; GO:0061631; GO:0070059; GO:0070936; GO:1903265 36876 XM_044316892.1 42 885 189 7 0 NA NA NA NA NA NA 36877 XM_044312207.1 154 76 234 244 192 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36878 XM_044312207.1 154 76 234 244 192 Q96AY4 1.05e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36879 XM_029328787.2 2616 1323 190 744 1023 NA NA NA NA NA NA 36880 XM_029336306.2 1491 1467 2041 2170 1581 NA NA NA NA NA NA 36881 XR_006392910.1 41 2 25 5 151 NA NA NA NA NA NA 36882 XM_029352312.2 14 9 0 29 13 Q9JIQ8 2.04e-55 Transmembrane protease serine 2 (EC 3.4.21.-) (Epitheliasin) (Plasmic transmembrane protein X) [Cleaved into: Transmembrane protease serine 2 non-catalytic chain; Transmembrane protease serine 2 catalytic chain] Mus musculus (Mouse) positive regulation of viral entry into host cell [GO:0046598]; protein autoprocessing [GO:0016540]; proteolysis [GO:0006508] GO:0004252; GO:0005044; GO:0005576; GO:0005654; GO:0005886; GO:0006508; GO:0016540; GO:0046598 36883 XM_044319258.1 947 205 0 406 256 Q86W24 4.96e-47 NACHT, LRR and PYD domains-containing protein 14 (Nucleotide-binding oligomerization domain protein 5) Homo sapiens (Human) cell differentiation [GO:0030154]; regulation of inflammatory response [GO:0050727]; spermatogenesis [GO:0007283] GO:0005524; GO:0005737; GO:0007283; GO:0030154; GO:0050727 36884 XM_044319130.1 324 306 483 414 591 Q6AZB8 9.82e-61 Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0004518; GO:0005634; GO:0005737; GO:0046872 36885 XM_029339151.2 36 10 69 21 61 NA NA NA NA NA NA 36886 XR_003823980.2 177 349 313 263 207 NA NA NA NA NA NA 36887 XM_029333979.2 0 0 16 0 26 A9C3R9 2.59e-116 All-trans-retinyl ester 13-cis isomerohydrolase (13cIMH) (EC 3.1.1.90) (Lutein isomerase) (Meso-zeaxanthin isomerase) (EC 5.3.3.22) (Retinal pigment epithelium-specific 65 kDa protein homolog B) (RPE56b) Danio rerio (Zebrafish) (Brachydanio rerio) retinoid metabolic process [GO:0001523]; zeaxanthin biosynthetic process [GO:1901827] GO:0001523; GO:0005789; GO:0005886; GO:0016702; GO:0016787; GO:0046872; GO:0050251; GO:1901827 36888 XM_029330392.2 615 498 225 453 261 P11833 0 Tubulin beta chain (Beta-tubulin) Paracentrotus lividus (Common sea urchin) microtubule-based process [GO:0007017] GO:0003924; GO:0005200; GO:0005525; GO:0005737; GO:0005874; GO:0007017; GO:0046872 36889 XR_003828240.2 187 211 146 135 126 NA NA NA NA NA NA 36890 XM_044320757.1 12 0 19 6 109 NA NA NA NA NA NA 36891 XR_003827081.2 15 0 0 0 23 NA NA NA NA NA NA 36892 XM_029350694.2 5990 4942 3893 7040 5673 NA NA NA NA NA NA 36893 XM_029342048.2 418 516 945 610 515 NA NA NA NA NA NA 36894 XM_044325091.1 492 1557 399 689 277 NA NA NA NA NA NA 36895 XM_044319427.1 4 0 4 2 27 NA NA NA NA NA NA 36896 XM_029329557.2 205 96 111 114 164 Q5GH73 5.18e-50 XK-related protein 6 Homo sapiens (Human) apoptotic process involved in development [GO:1902742]; engulfment of apoptotic cell [GO:0043652]; phosphatidylserine exposure on apoptotic cell surface [GO:0070782] GO:0005886; GO:0016020; GO:0043652; GO:0070782; GO:1902742 36897 XM_029339727.2 0 0 0 0 85 NA NA NA NA NA NA 36898 XM_029335942.2 445 241 300 458 662 P30974 4.62e-27 Tachykinin-like peptides receptor 86C (NKD) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; inter-male aggressive behavior [GO:0002121]; neuropeptide signaling pathway [GO:0007218]; tachykinin receptor signaling pathway [GO:0007217] GO:0002121; GO:0004995; GO:0005886; GO:0007186; GO:0007217; GO:0007218; GO:0008188; GO:0016020 36899 XM_044317829.1 108 447 279 3 93 NA NA NA NA NA NA 36900 XM_029333392.2 809 917 562 1268 725 NA NA NA NA NA NA 36901 XM_029330005.2 40 3 13 86 31 Q9TTT5 2.55e-84 Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3) Oryctolagus cuniculus (Rabbit) protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0008076; GO:0030425; GO:0034765; GO:0042383; GO:0046872; GO:0051260 36902 XM_044314995.1 8 16 0 10 0 NA NA NA NA NA NA 36903 XM_029341334.2 1489 1390 2185 2428 937 Q8BQH6 9.53e-50 CUB domain-containing protein 2 Mus musculus (Mouse) NA GO:0005576 36904 XR_006391589.1 272 155 3 190 143 NA NA NA NA NA NA 36905 XM_029340303.2 18 0 62 39 89 Q15434 2.35e-80 RNA-binding motif, single-stranded-interacting protein 2 (Suppressor of CDC2 with RNA-binding motif 3) Homo sapiens (Human) RNA processing [GO:0006396] GO:0003723; GO:0003730; GO:0005634; GO:0005829; GO:0006396; GO:0008143; GO:0008266; GO:1990904 36906 XM_029326327.2 5 5 16 2 4 NA NA NA NA NA NA 36907 XM_029355772.2 52 0 0 0 0 C0HL12 6.24e-31 Adhesion G protein-coupled receptor B1 (Brain-specific angiogenesis inhibitor 1) [Cleaved into: Vasculostatin-120 (Vstat120); Vasculostatin-40 (Vstat-40)] Rattus norvegicus (Rat) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; apoptotic cell clearance [GO:0043277]; cell surface receptor signaling pathway [GO:0007166]; defense response to Gram-negative bacterium [GO:0050829]; engulfment of apoptotic cell [GO:0043652]; innate immune response [GO:0045087]; muscle organ development [GO:0007517]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein ubiquitination [GO:0031397]; nervous system development [GO:0007399]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of synapse assembly [GO:0051965]; postsynaptic actin cytoskeleton organization [GO:0098974]; regulation of synaptic plasticity [GO:0048167] GO:0001530; GO:0001786; GO:0001891; GO:0004888; GO:0004930; GO:0005615; GO:0005886; GO:0005925; GO:0006910; GO:0006911; GO:0007166; GO:0007189; GO:0007399; GO:0007517; GO:0010596; GO:0014069; GO:0016525; GO:0030165; GO:0030425; GO:0031397; GO:0042177; GO:0043197; GO:0043277; GO:0043652; GO:0045087; GO:0045211; GO:0048167; GO:0048471; GO:0050829; GO:0051965; GO:0098974; GO:0098978; GO:1901741; GO:1903428 36908 XM_044313719.1 7 2 0 0 6 NA NA NA NA NA NA 36909 XM_044326475.1 178 143 93 144 168 Q9Y5R4 1.33e-69 MTRF1L release factor glutamine methyltransferase (EC 2.1.1.297) (HemK methyltransferase family member 1) (M.HsaHemKP) Homo sapiens (Human) DNA methylation [GO:0006306] GO:0003677; GO:0005739; GO:0006306; GO:0008170; GO:0008276; GO:0008757; GO:0102559 36910 XM_044316462.1 0 6 5 0 6 NA NA NA NA NA NA 36911 XM_029344321.2 187 411 121 433 246 A2VDD2 7.89e-48 Dynein light chain Tctex-type 5-B (Tctex1 domain-containing protein 1-B) Xenopus laevis (African clawed frog) NA NA 36912 XM_029326866.2 121 46 28 34 58 O54853 6.83e-149 Potassium voltage-gated channel subfamily H member 6 (Ether-a-go-go-related gene potassium channel 2) (ERG-2) (Eag-related protein 2) (Ether-a-go-go-related protein 2) (Voltage-gated potassium channel subunit Kv11.2) Rattus norvegicus (Rat) membrane repolarization during action potential [GO:0086011]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307] GO:0005242; GO:0005249; GO:0005267; GO:0005886; GO:0006813; GO:0034765; GO:0042391; GO:0044877; GO:0060307; GO:0071805; GO:0086011; GO:0086091 36913 XM_044327293.1 61 80 80 377 61 NA NA NA NA NA NA 36914 XM_044312260.1 0 0 0 0 8 NA NA NA NA NA NA 36915 XM_029325096.2 878 890 339 738 387 Q9D3W1 4.92e-86 Radial spoke head 14 homolog (Rhabdoid tumor deletion region protein 1) Mus musculus (Mouse) NA NA 36916 XM_029340542.2 522 361 285 432 532 Q9Y253 6.28e-154 DNA polymerase eta (EC 2.7.7.7) (RAD30 homolog A) (Xeroderma pigmentosum variant type protein) Homo sapiens (Human) cellular response to UV-C [GO:0071494]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; pyrimidine dimer repair [GO:0006290]; regulation of DNA repair [GO:0006282]; response to radiation [GO:0009314]; response to UV-C [GO:0010225] GO:0000731; GO:0003684; GO:0003887; GO:0005634; GO:0005654; GO:0005657; GO:0005829; GO:0006260; GO:0006281; GO:0006282; GO:0006290; GO:0009314; GO:0010225; GO:0035861; GO:0042276; GO:0046872; GO:0070987; GO:0071494 36917 XM_044324232.1 3990 0 142 5588 1435 NA NA NA NA NA NA 36918 XR_006397460.1 176 101 163 130 390 NA NA NA NA NA NA 36919 XM_044325097.1 7 0 12 1 8 NA NA NA NA NA NA 36920 XM_029330649.2 18 0 6 0 0 Q32KJ6 0 N-acetylgalactosamine-6-sulfatase (EC 3.1.6.4) (Chondroitinsulfatase) (Chondroitinase) (Galactose-6-sulfate sulfatase) (N-acetylgalactosamine-6-sulfate sulfatase) (GalNAc6S sulfatase) Rattus norvegicus (Rat) NA GO:0004065; GO:0005764; GO:0008484; GO:0043890; GO:0046872 36921 XM_044308730.1 0 3 0 6 9 NA NA NA NA NA NA 36922 XM_044310840.1 157 93 102 79 6 Q7RTR2 4.95e-76 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 36923 XM_044310840.1 157 93 102 79 6 Q7RTR2 2.97e-74 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 36924 XM_044310840.1 157 93 102 79 6 Q7RTR2 1.16e-66 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 36925 XM_029345926.2 58 0 0 26 75 O15439 0 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 36926 XM_044309639.1 159 208 55 103 111 NA NA NA NA NA NA 36927 XM_029338362.2 293 342 209 145 167 NA NA NA NA NA NA 36928 XM_044324023.1 1213 946 580 1130 692 Q4VSN4 3.22e-80 Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein kinase) (Dusty PK) (Receptor-interacting serine/threonine-protein kinase 5) Canis lupus familiaris (Dog) (Canis familiaris) cellular response to fibroblast growth factor stimulus [GO:0044344]; negative regulation of apoptotic process [GO:0043066]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast growth factor receptor signaling pathway [GO:0045743]; positive regulation of kinase activity [GO:0033674] GO:0004674; GO:0004712; GO:0004713; GO:0005524; GO:0005737; GO:0016323; GO:0016324; GO:0033674; GO:0043066; GO:0044344; GO:0045743; GO:0070161; GO:0070374; GO:0106310 36929 XR_006392761.1 436 94 277 301 2042 NA NA NA NA NA NA 36930 XM_029330652.2 828 493 731 1333 1625 A1L1W9 6.81e-48 Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10) Danio rerio (Zebrafish) (Brachydanio rerio) aromatic amino acid transport [GO:0015801]; thyroid hormone transport [GO:0070327] GO:0005302; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0070327 36931 XR_006397747.1 0 0 16 0 0 NA NA NA NA NA NA 36932 XM_029357739.2 0 69 85 173 270 Q8AYG3 5.26e-92 Dual specificity protein kinase Ttk (EC 2.7.12.1) (Mitotic checkpoint serine/threonine-protein kinase Mps1) (Monopolar spindle protein 1) (Protein nightcap) Danio rerio (Zebrafish) (Brachydanio rerio) anatomical structure homeostasis [GO:0060249]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; female meiosis chromosome segregation [GO:0016321]; fin regeneration [GO:0031101]; male meiosis chromosome segregation [GO:0007060]; meiotic spindle assembly checkpoint signaling [GO:0033316]; mitotic spindle assembly checkpoint signaling [GO:0007094]; negative regulation of exit from mitosis [GO:0001100]; peptidyl-serine phosphorylation [GO:0018105]; protein localization to kinetochore [GO:0034501]; tissue regeneration [GO:0042246] GO:0000776; GO:0001100; GO:0004674; GO:0004712; GO:0004713; GO:0005524; GO:0005634; GO:0007059; GO:0007060; GO:0007094; GO:0016321; GO:0018105; GO:0031101; GO:0033316; GO:0034501; GO:0042246; GO:0046872; GO:0051301; GO:0060249; GO:0106310 36933 XM_029333172.2 115 87 79 140 168 Q3TCX3 7.25e-67 KH homology domain-containing protein 4 (Brings lots of money 7) (Pre-mRNA splicing factor protein Khdc4) Mus musculus (Mouse) mRNA splice site selection [GO:0006376] GO:0003723; GO:0005634; GO:0005654; GO:0005681; GO:0005737; GO:0006376 36934 XM_029341972.2 144 0 0 26 85 Q8N5H7 3.34e-29 SH2 domain-containing protein 3C (Cas/HEF1-associated signal transducer) (Chat-H) (Novel SH2-containing protein 3) (SH2 domain-containing Eph receptor-binding protein 1) (SHEP1) Homo sapiens (Human) JNK cascade [GO:0007254]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; small GTPase mediated signal transduction [GO:0007264] GO:0001784; GO:0005085; GO:0005829; GO:0007254; GO:0007264; GO:0030424; GO:0032587; GO:0033138 36935 XM_044317884.1 35 167 29 69 11 P54131 1.99e-73 Neuronal acetylcholine receptor subunit alpha-7 Bos taurus (Bovine) calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; cognition [GO:0050890]; ion transmembrane transport [GO:0034220]; negative regulation of tumor necrosis factor production [GO:0032720]; nervous system process [GO:0050877]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAPK cascade [GO:0043410]; regulation of membrane potential [GO:0042391]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271] GO:0001540; GO:0001666; GO:0005231; GO:0005886; GO:0005892; GO:0006816; GO:0006874; GO:0007165; GO:0007268; GO:0007271; GO:0008284; GO:0015464; GO:0015643; GO:0017081; GO:0022848; GO:0030594; GO:0032720; GO:0034220; GO:0035094; GO:0042166; GO:0042391; GO:0042803; GO:0043005; GO:0043410; GO:0045202; GO:0045211; GO:0045766; GO:0050877; GO:0050890; GO:1904315 36936 XR_006392299.1 47 46 7 99 18 NA NA NA NA NA NA 36937 XM_029350538.2 0 184 142 136 0 NA NA NA NA NA NA 36938 XM_044326246.1 26 9 5 63 27 NA NA NA NA NA NA 36939 XR_006394453.1 380 82 33 61 21 NA NA NA NA NA NA 36940 XM_044316408.1 650 556 353 870 431 Q7RTR2 2.98e-55 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 36941 XM_044316408.1 650 556 353 870 431 Q7RTR2 4.91e-51 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 36942 XM_044316408.1 650 556 353 870 431 Q7RTR2 2.04e-40 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 36943 XM_044316408.1 650 556 353 870 431 Q7RTR2 1.65e-30 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 36944 XM_029355725.2 2259 2741 1546 1981 1352 Q9Y3E0 1.54e-35 Vesicle transport protein GOT1B (Germ cell tumor 2) (Golgi transport 1 homolog B) (Putative NF-kappa-B-activating protein 470) (hGOT1a) Homo sapiens (Human) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147] GO:0000139; GO:0005783; GO:0005829; GO:0006888; GO:0015031; GO:0016020; GO:0032991; GO:0042147; GO:0043123 36945 XM_029339322.2 64 0 102 9 309 P0CT39 5.88e-90 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 36946 XM_044321222.1 34 59 57 134 57 NA NA NA NA NA NA 36947 XM_029347883.2 2942 2495 1601 2379 2947 O75840 1.17e-48 Krueppel-like factor 7 (Ubiquitous krueppel-like factor) Homo sapiens (Human) axon guidance [GO:0007411]; axonogenesis [GO:0007409]; dendrite morphogenesis [GO:0048813]; glucose homeostasis [GO:0042593]; negative regulation of adipose tissue development [GO:1904178]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of epidermal cell differentiation [GO:0045604]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000785; GO:0000978; GO:0000981; GO:0001228; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0007409; GO:0007411; GO:0008270; GO:0042593; GO:0045604; GO:0045944; GO:0048813; GO:0061179; GO:1904178 36948 XM_029325525.2 264 288 383 288 462 NA NA NA NA NA NA 36949 XM_044313770.1 309 459 138 133 316 Q567B1 6.36e-89 Ubiquitin thioesterase OTU1 (EC 3.4.19.12) Danio rerio (Zebrafish) (Brachydanio rerio) endoplasmic reticulum unfolded protein response [GO:0030968]; macroautophagy [GO:0016236]; protein deubiquitination [GO:0016579]; protein K11-linked deubiquitination [GO:0035871]; protein K27-linked deubiquitination [GO:1990167]; protein K29-linked deubiquitination [GO:0035523]; protein K33-linked deubiquitination [GO:1990168]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0004843; GO:0005737; GO:0016236; GO:0016579; GO:0030433; GO:0030968; GO:0035523; GO:0035871; GO:0046872; GO:0070536; GO:0071108; GO:1990167; GO:1990168 36950 XM_029323672.2 593 631 326 1009 962 NA NA NA NA NA NA 36951 XM_029345377.2 539 461 336 357 382 NA NA NA NA NA NA 36952 XM_029350714.2 58 27 5 39 64 A4FUD4 4e-84 Peroxisome assembly protein 12 (Peroxin-12) Bos taurus (Bovine) peroxisome organization [GO:0007031]; protein import into peroxisome matrix [GO:0016558]; protein import into peroxisome matrix, receptor recycling [GO:0016562]; protein monoubiquitination [GO:0006513] GO:0004842; GO:0005778; GO:0006513; GO:0007031; GO:0008022; GO:0008270; GO:0016558; GO:0016562; GO:1990429; GO:1990757 36953 XM_044313134.1 169 90 46 87 40 NA NA NA NA NA NA 36954 XM_029344544.2 184 0 145 89 327 Q5M9N0 6.32e-29 Coiled-coil domain-containing protein 158 Homo sapiens (Human) NA NA 36955 XM_044320840.1 47 4 15 34 87 NA NA NA NA NA NA 36956 XM_029351975.2 242 286 169 244 261 Q641W3 5.68e-33 FMR1-interacting protein NUFIP1 (Nuclear FMRP-interacting protein 1) Rattus norvegicus (Rat) box C/D snoRNP assembly [GO:0000492]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000492; GO:0001650; GO:0003723; GO:0005634; GO:0005726; GO:0008023; GO:0016363; GO:0030515; GO:0030674; GO:0032991; GO:0042802; GO:0045202; GO:0045944; GO:0046872; GO:0048786; GO:0051117; GO:0070761 36957 XM_044327350.1 75 19 16 156 43 NA NA NA NA NA NA 36958 XM_044326155.1 48 21 31 1 20 NA NA NA NA NA NA 36959 XM_044316630.1 67 14 40 34 36 NA NA NA NA NA NA 36960 XM_044327500.1 27 0 0 2 97 NA NA NA NA NA NA 36961 XM_044320540.1 995 770 644 807 757 Q8N3Z3 8.05e-38 GTP-binding protein 8 Homo sapiens (Human) NA GO:0005525; GO:0005739; GO:0046872 36962 XM_029346852.2 240 129 122 184 145 B3DMA2 0 Acyl-CoA dehydrogenase family member 11 (ACAD-11) (EC 1.3.8.-) Rattus norvegicus (Rat) fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539] GO:0003995; GO:0004466; GO:0005634; GO:0005737; GO:0005739; GO:0005777; GO:0017099; GO:0031966; GO:0033539; GO:0050660; GO:0070991 36963 XM_029347163.2 104 15 12 12 24 P70426 2.58e-37 GTP-binding protein Rit1 (EC 3.6.5.2) (Ras-like protein expressed in many tissues) (Ras-like without CAAX protein 1) Mus musculus (Mouse) Ras protein signal transduction [GO:0007265] GO:0003924; GO:0003925; GO:0005516; GO:0005525; GO:0005886; GO:0007265; GO:0019003 36964 XM_044319670.1 93 18 0 0 6 Q9CYL5 4.26e-27 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Mus musculus (Mouse) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070374 36965 XR_006396953.1 396 322 371 344 875 NA NA NA NA NA NA 36966 XM_044309623.1 10 7 54 10 147 Q9CL21 3.7e-26 ATP-dependent DNA helicase RecQ (EC 3.6.4.12) Pasteurella multocida (strain Pm70) DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; SOS response [GO:0009432] GO:0003677; GO:0005524; GO:0006260; GO:0006281; GO:0006310; GO:0009432; GO:0016887; GO:0043138 36967 XR_003828564.2 1355 1172 841 1211 822 NA NA NA NA NA NA 36968 XM_029330325.2 0 0 10 0 2 NA NA NA NA NA NA 36969 XM_044319068.1 0 0 65 45 64 Q9VEU6 2.63e-110 Soluble guanylate cyclase 89Da (EC 4.6.1.2) Drosophila melanogaster (Fruit fly) cGMP-mediated signaling [GO:0019934]; nitric oxide-cGMP-mediated signaling pathway [GO:0038060]; response to hypoxia [GO:0001666]; response to oxygen levels [GO:0070482]; response to reactive oxygen species [GO:0000302] GO:0000302; GO:0001666; GO:0004383; GO:0005525; GO:0008074; GO:0019899; GO:0019934; GO:0020037; GO:0038060; GO:0046872; GO:0070482 36970 XR_006395255.1 449 270 268 217 369 NA NA NA NA NA NA 36971 XM_029340579.2 1 0 4 8 31 NA NA NA NA NA NA 36972 XM_044323640.1 0 7 0 3 0 Q6AZB8 5.9e-21 Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0004518; GO:0005634; GO:0005737; GO:0046872 36973 XM_044309170.1 295 501 335 718 467 NA NA NA NA NA NA 36974 XM_029324075.2 3 18 13 141 2 NA NA NA NA NA NA 36975 XM_029330304.2 183 131 231 1015 121 Q9IA88 1.32e-156 Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2) Gallus gallus (Chicken) intracellular signal transduction [GO:0035556]; microtubule cytoskeleton organization [GO:0000226]; protein phosphorylation [GO:0006468]; regulation of insulin receptor signaling pathway [GO:0046626] GO:0000226; GO:0000287; GO:0004674; GO:0005524; GO:0005737; GO:0006468; GO:0035556; GO:0046626; GO:0050321; GO:0106310 36976 XM_044321291.1 21 0 0 0 47 A6QLD2 6.34e-52 Olfactomedin-like protein 2B Bos taurus (Bovine) extracellular matrix organization [GO:0030198]; signal transduction [GO:0007165] GO:0005615; GO:0007165; GO:0030198; GO:0031012; GO:0042802; GO:0050840 36977 XM_044327189.1 91 27 92 166 136 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36978 XM_044327189.1 91 27 92 166 136 Q96AY4 2.65e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36979 XM_029332966.2 0 0 18 0 0 Q5ZLD7 0 Vacuolar protein sorting-associated protein 53 homolog Gallus gallus (Chicken) endocytic recycling [GO:0032456]; protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147] GO:0000938; GO:0005829; GO:0010008; GO:0015031; GO:0032456; GO:0042147; GO:0055037; GO:1990745 36980 XM_044317412.1 120 62 92 132 81 NA NA NA NA NA NA 36981 XM_029350487.2 1474 1168 813 768 730 Q9N0E7 0 Molybdenum cofactor sulfurase (MCS) (MOS) (MoCo sulfurase) (EC 2.8.1.9) (Molybdenum cofactor sulfurtransferase) Bos taurus (Bovine) Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdopterin cofactor metabolic process [GO:0043545] GO:0006777; GO:0008265; GO:0016829; GO:0030151; GO:0030170; GO:0043545; GO:0102867 36982 XM_044317465.1 2029 659 792 1562 1207 Q4R3Y4 0 Long-chain fatty acid transport protein 4 (FATP-4) (Fatty acid transport protein 4) (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Solute carrier family 27 member 4) (Very long-chain acyl-CoA synthetase 4) (ACSVL4) (EC 6.2.1.-) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0000166; GO:0005789; GO:0047676; GO:1901480 36983 XM_029341894.2 1237 1135 644 997 823 Q6GLT8 1.39e-134 Fumarylacetoacetate hydrolase domain-containing protein 2 (EC 3.-.-.-) Xenopus laevis (African clawed frog) NA GO:0016787; GO:0046872 36984 XM_029358422.2 48 0 64 0 0 NA NA NA NA NA NA 36985 XM_029357176.2 78 67 20 60 59 P61315 1.73e-37 Galactose-3-O-sulfotransferase 3 (Gal3ST-3) (EC 2.8.2.-) (Beta-galactose-3-O-sulfotransferase 3) (Gal-beta-1, 3-GalNAc 3'-sulfotransferase 3) Mus musculus (Mouse) glycolipid biosynthetic process [GO:0009247] GO:0001733; GO:0008146; GO:0009247; GO:0032580; GO:0050694 36986 XM_044324457.1 71 27 56 81 7 NA NA NA NA NA NA 36987 XM_029332670.2 2863 1876 1754 2790 3173 Q6P2W5 1.27e-22 Arginine and glutamate-rich protein 1 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA NA 36988 XM_029348106.2 0 15 0 59 0 P47793 1.79e-130 Protein Wnt-4a Danio rerio (Zebrafish) (Brachydanio rerio) canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; cell migration involved in gastrulation [GO:0042074]; embryonic viscerocranium morphogenesis [GO:0048703]; habenula development [GO:0021986]; heart development [GO:0007507]; neuron differentiation [GO:0030182]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of axon extension involved in axon guidance [GO:0048841]; sensory epithelium regeneration [GO:0070654] GO:0005109; GO:0005125; GO:0005615; GO:0007507; GO:0021986; GO:0030182; GO:0042074; GO:0045165; GO:0045893; GO:0048703; GO:0048841; GO:0060070; GO:0070654 36989 XM_044323918.1 66 0 0 23 185 P07911 1.91e-45 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Homo sapiens (Human) antibacterial innate immune response [GO:0140367]; apoptotic signaling pathway [GO:0097190]; autophagy [GO:0006914]; cellular calcium ion homeostasis [GO:0006874]; cellular chloride ion homeostasis [GO:0030644]; cellular defense response [GO:0006968]; cellular phosphate ion homeostasis [GO:0030643]; cellular response to unfolded protein [GO:0034620]; cellular sodium ion homeostasis [GO:0006883]; chaperone-mediated protein folding [GO:0061077]; citric acid secretion [GO:0046720]; collecting duct development [GO:0072044]; connective tissue replacement [GO:0097709]; creatinine homeostasis [GO:0097273]; defense response to Gram-negative bacterium [GO:0050829]; endoplasmic reticulum organization [GO:0007029]; glomerular filtration [GO:0003094]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; juxtaglomerular apparatus development [GO:0072051]; leukocyte cell-cell adhesion [GO:0007159]; lipid metabolic process [GO:0006629]; metanephric ascending thin limb development [GO:0072218]; metanephric distal convoluted tubule development [GO:0072221]; metanephric thick ascending limb development [GO:0072233]; micturition [GO:0060073]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell population proliferation [GO:0008285]; neutrophil migration [GO:1990266]; organ or tissue specific immune response [GO:0002251]; peptidyl-threonine phosphorylation [GO:0018107]; potassium ion homeostasis [GO:0055075]; protein localization to vacuole [GO:0072665]; protein transport into plasma membrane raft [GO:0044861]; regulation of blood pressure [GO:0008217]; regulation of protein transport [GO:0051223]; regulation of urine volume [GO:0035809]; renal sodium ion absorption [GO:0070294]; renal urate salt excretion [GO:0097744]; renal water homeostasis [GO:0003091]; response to lipopolysaccharide [GO:0032496]; response to water deprivation [GO:0009414]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; ubiquitin-dependent ERAD pathway [GO:0030433]; urate transport [GO:0015747]; urea transmembrane transport [GO:0071918] GO:0000922; GO:0002251; GO:0003091; GO:0003094; GO:0005201; GO:0005509; GO:0005615; GO:0005783; GO:0005796; GO:0005929; GO:0006629; GO:0006874; GO:0006883; GO:0006914; GO:0006954; GO:0006968; GO:0007029; GO:0007157; GO:0007159; GO:0008217; GO:0008285; GO:0008380; GO:0009410; GO:0009414; GO:0009986; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0018107; GO:0019864; GO:0019898; GO:0030433; GO:0030643; GO:0030644; GO:0032496; GO:0033209; GO:0033555; GO:0034620; GO:0035809; GO:0044861; GO:0046720; GO:0050829; GO:0051223; GO:0055075; GO:0060073; GO:0060170; GO:0061077; GO:0070062; GO:0070294; GO:0071918; GO:0072044; GO:0072051; GO:0072218; GO:0072221; GO:0072233; GO:0072665; GO:0097190; GO:0097273; GO:0097709; GO:0097744; GO:0140367; GO:1990266 36990 XM_029340744.2 583 410 292 458 172 P0CN91 3.66e-27 Sterol 3-beta-glucosyltransferase (EC 2.4.1.173) (Autophagy-related protein 26) Cryptococcus neoformans var. neoformans serotype D (strain B-3501A) (Filobasidiella neoformans) carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; sterol biosynthetic process [GO:0016126] GO:0005737; GO:0005975; GO:0016020; GO:0016126; GO:0016906; GO:0030259; GO:0102202; GO:0102203; GO:0102205 36991 XM_044321009.1 0 31 0 0 0 NA NA NA NA NA NA 36992 XM_044317365.1 7563 4607 5090 7708 5742 Q9Y4G6 0 Talin-2 Homo sapiens (Human) cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-cell junction assembly [GO:0007043] GO:0001726; GO:0003779; GO:0005178; GO:0005198; GO:0005200; GO:0005737; GO:0005886; GO:0005925; GO:0007043; GO:0007155; GO:0015629; GO:0045202; GO:0051015; GO:0098609 36993 XM_044307235.1 6665 4184 3422 2911 2430 Q7M456 2.26e-34 Ribonuclease Oy (RNase Oy) (EC 3.1.27.-) Crassostrea gigas (Pacific oyster) (Crassostrea angulata) NA GO:0003723; GO:0005576; GO:0033897 36994 XM_029358555.2 51 107 15 63 78 NA NA NA NA NA NA 36995 XM_044314136.1 7 27 3 18 12 NA NA NA NA NA NA 36996 XM_029324466.2 602 385 295 434 378 Q3MQ06 6.81e-119 Autophagy protein 5 Rattus norvegicus (Rat) aggrephagy [GO:0035973]; antigen processing and presentation of endogenous antigen [GO:0019883]; apoptotic process [GO:0006915]; autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; autophagy of nucleus [GO:0044804]; blood vessel remodeling [GO:0001974]; C-terminal protein lipidation [GO:0006501]; cardiac muscle cell apoptotic process [GO:0010659]; cellular response to nitrogen starvation [GO:0006995]; cellular response to nitrosative stress [GO:0071500]; cellular response to starvation [GO:0009267]; chaperone-mediated autophagy [GO:0061684]; establishment of localization in cell [GO:0051649]; heart contraction [GO:0060047]; macroautophagy [GO:0016236]; mucus secretion [GO:0070254]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of cell death [GO:0060548]; negative regulation of defense response to virus [GO:0050687]; negative regulation of histone H4-K16 acetylation [GO:2000619]; negative regulation of innate immune response [GO:0045824]; negative regulation of phagocytosis [GO:0050765]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of type I interferon production [GO:0032480]; negative stranded viral RNA replication [GO:0039689]; negative thymic T cell selection [GO:0045060]; otolith development [GO:0048840]; positive regulation of mucus secretion [GO:0070257]; positive regulation of viral translation [GO:1904973]; post-translational protein modification [GO:0043687]; protein lipidation [GO:0006497]; protein lipidation involved in autophagosome assembly [GO:0061739]; protein ubiquitination [GO:0016567]; regulation of autophagosome maturation [GO:1901096]; regulation of cilium assembly [GO:1902017]; regulation of cytokine production involved in immune response [GO:0002718]; regulation of reactive oxygen species metabolic process [GO:2000377]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; response to fluoride [GO:1902617]; response to fungus [GO:0009620]; response to iron(II) ion [GO:0010040]; response to xenobiotic stimulus [GO:0009410]; vasodilation [GO:0042311]; ventricular cardiac muscle cell development [GO:0055015] GO:0000045; GO:0000422; GO:0001974; GO:0002718; GO:0005737; GO:0005776; GO:0005930; GO:0006497; GO:0006501; GO:0006914; GO:0006915; GO:0006995; GO:0009267; GO:0009410; GO:0009620; GO:0010040; GO:0010659; GO:0010667; GO:0016020; GO:0016236; GO:0016567; GO:0019883; GO:0030424; GO:0031397; GO:0032480; GO:0032991; GO:0034045; GO:0034274; GO:0035973; GO:0039689; GO:0042311; GO:0043066; GO:0043687; GO:0044233; GO:0044804; GO:0045060; GO:0045824; GO:0048840; GO:0050687; GO:0050765; GO:0051279; GO:0051649; GO:0055015; GO:0060047; GO:0060548; GO:0061684; GO:0061739; GO:0070254; GO:0070257; GO:0071500; GO:1901096; GO:1902017; GO:1902617; GO:1904973; GO:1990234; GO:2000377; GO:2000378; GO:2000619 36997 XM_029334649.2 29 1232 1157 349 100 Q96DM1 3.41e-68 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 36998 XM_044309754.1 0 0 0 45 35 O75581 0 Low-density lipoprotein receptor-related protein 6 (LRP-6) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; chemical synaptic transmission [GO:0007268]; dopaminergic neuron differentiation [GO:0071542]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001933; GO:0005041; GO:0005102; GO:0005109; GO:0005576; GO:0005783; GO:0005886; GO:0006469; GO:0007204; GO:0007268; GO:0009986; GO:0014029; GO:0014033; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0031410; GO:0031901; GO:0034392; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043434; GO:0044335; GO:0044340; GO:0045121; GO:0045202; GO:0045787; GO:0045893; GO:0045944; GO:0051091; GO:0060070; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072659; GO:0090118; GO:0090244; GO:0098609; GO:1904928; GO:1904948; GO:1904953; GO:1990851; GO:1990909 36999 XM_044309754.1 0 0 0 45 35 O75581 1.28e-168 Low-density lipoprotein receptor-related protein 6 (LRP-6) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; chemical synaptic transmission [GO:0007268]; dopaminergic neuron differentiation [GO:0071542]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001933; GO:0005041; GO:0005102; GO:0005109; GO:0005576; GO:0005783; GO:0005886; GO:0006469; GO:0007204; GO:0007268; GO:0009986; GO:0014029; GO:0014033; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0031410; GO:0031901; GO:0034392; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043434; GO:0044335; GO:0044340; GO:0045121; GO:0045202; GO:0045787; GO:0045893; GO:0045944; GO:0051091; GO:0060070; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072659; GO:0090118; GO:0090244; GO:0098609; GO:1904928; GO:1904948; GO:1904953; GO:1990851; GO:1990909 37000 XM_044328262.1 5 11 0 14 2 NA NA NA NA NA NA 37001 XR_006393426.1 37 144 101 213 163 NA NA NA NA NA NA 37002 XM_029348599.2 197 837 732 983 238 Q6DIE2 0 Nuclear cap-binding protein subunit 1 (80 kDa nuclear cap-binding protein) (CBP80) (NCBP 80 kDa subunit) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) 7-methylguanosine mRNA capping [GO:0006370]; mRNA export from nucleus [GO:0006406]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of mRNA 3'-end processing [GO:0031442]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; regulation of translational initiation [GO:0006446]; RNA splicing [GO:0008380]; RNA-mediated gene silencing [GO:0031047] GO:0000184; GO:0000339; GO:0005634; GO:0005737; GO:0005845; GO:0005846; GO:0006370; GO:0006406; GO:0006446; GO:0008380; GO:0031047; GO:0031442; GO:0098789 37003 XM_029338233.2 1411 1428 1543 2138 732 NA NA NA NA NA NA 37004 XM_044314111.1 0 8 28 0 0 NA NA NA NA NA NA 37005 XM_029347109.2 64 40 41 35 92 NA NA NA NA NA NA 37006 XM_044312916.1 6 25 61 49 17 NA NA NA NA NA NA 37007 XM_029336838.2 0 3 0 22 12 O42409 7.06e-95 Zinc finger protein Gfi-1b (Growth factor-independent protein 1B) Gallus gallus (Chicken) chromatin organization [GO:0006325]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001227; GO:0005654; GO:0006325; GO:0006357; GO:0046872 37008 XM_029336838.2 0 3 0 22 12 O42409 1.96e-21 Zinc finger protein Gfi-1b (Growth factor-independent protein 1B) Gallus gallus (Chicken) chromatin organization [GO:0006325]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001227; GO:0005654; GO:0006325; GO:0006357; GO:0046872 37009 XM_044327636.1 3 8 1 8 24 NA NA NA NA NA NA 37010 XM_044316644.1 41 91 23 57 59 NA NA NA NA NA NA 37011 XM_029323508.2 31 10 22 7 13 NA NA NA NA NA NA 37012 XM_044318882.1 21 49 7 0 0 NA NA NA NA NA NA 37013 XM_044310446.1 47 0 46 23 216 O77469 3.37e-21 Fibulin-1 Caenorhabditis elegans extracellular matrix organization [GO:0030198]; positive regulation of locomotion [GO:0040017]; protein localization [GO:0008104] GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0008104; GO:0016504; GO:0030198; GO:0040017 37014 XM_044312739.1 258 183 141 98 147 Q923S8 0 4'-phosphopantetheine phosphatase (EC 3.1.3.-) (Inactive pantothenic acid kinase 4) (rPanK4) Rattus norvegicus (Rat) coenzyme A biosynthetic process [GO:0015937] GO:0004594; GO:0005524; GO:0005634; GO:0005829; GO:0015937; GO:0016787; GO:0046872 37015 XM_029338648.2 4 29 0 2 0 NA NA NA NA NA NA 37016 XM_044323665.1 0 9 21 60 53 NA NA NA NA NA NA 37017 XM_044326913.1 0 0 22 28 0 NA NA NA NA NA NA 37018 XM_029358453.2 7 2 2 2 0 P49582 6.07e-78 Neuronal acetylcholine receptor subunit alpha-7 Mus musculus (Mouse) acetylcholine receptor signaling pathway [GO:0095500]; associative learning [GO:0008306]; B cell activation [GO:0042113]; behavioral response to ethanol [GO:0048149]; behavioral response to nicotine [GO:0035095]; calcium ion transport [GO:0006816]; chemical synaptic transmission [GO:0007268]; dendrite arborization [GO:0140059]; dendritic spine organization [GO:0097061]; endocytosis [GO:0006897]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; generation of ovulation cycle rhythm [GO:0060112]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; learning or memory [GO:0007611]; membrane depolarization [GO:0051899]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; modulation of excitatory postsynaptic potential [GO:0098815]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of tumor necrosis factor production [GO:0032720]; nervous system process [GO:0050877]; neuronal action potential [GO:0019228]; ovulation cycle [GO:0042698]; positive regulation of acetylcholine biosynthetic process [GO:1905923]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of CoA-transferase activity [GO:1905920]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure [GO:0001988]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of amyloid fibril formation [GO:1905906]; regulation of inflammatory response [GO:0050727]; regulation of membrane potential [GO:0042391]; regulation of neuron death [GO:1901214]; regulation of nitric oxide metabolic process [GO:0080164]; regulation of norepinephrine secretion [GO:0014061]; regulation of response to drug [GO:2001023]; regulation of synapse structural plasticity [GO:0051823]; regulation of synaptic transmission, cholinergic [GO:0032222]; regulation of synaptic transmission, dopaminergic [GO:0032225]; response to acetylcholine [GO:1905144]; response to amyloid-beta [GO:1904645]; response to cold [GO:0009409]; response to ethanol [GO:0045471]; response to food [GO:0032094]; response to nicotine [GO:0035094]; sensory processing [GO:0050893]; signal transduction [GO:0007165]; synapse organization [GO:0050808]; synaptic transmission, cholinergic [GO:0007271]; T cell activation [GO:0042110] GO:0001540; GO:0001933; GO:0001934; GO:0001988; GO:0005216; GO:0005231; GO:0005737; GO:0005886; GO:0005892; GO:0006811; GO:0006816; GO:0006897; GO:0007165; GO:0007268; GO:0007271; GO:0007611; GO:0007613; GO:0008179; GO:0008306; GO:0009409; GO:0009897; GO:0010628; GO:0014061; GO:0014069; GO:0015464; GO:0015643; GO:0016020; GO:0016324; GO:0017081; GO:0019228; GO:0019901; GO:0022848; GO:0030317; GO:0030424; GO:0030425; GO:0030426; GO:0030594; GO:0030673; GO:0032094; GO:0032222; GO:0032225; GO:0032279; GO:0032691; GO:0032715; GO:0032720; GO:0033138; GO:0034220; GO:0035094; GO:0035095; GO:0042110; GO:0042113; GO:0042166; GO:0042391; GO:0042698; GO:0042734; GO:0042803; GO:0043005; GO:0043025; GO:0043197; GO:0043198; GO:0044853; GO:0045121; GO:0045202; GO:0045211; GO:0045471; GO:0048149; GO:0050727; GO:0050728; GO:0050804; GO:0050808; GO:0050877; GO:0050893; GO:0051117; GO:0051247; GO:0051649; GO:0051823; GO:0051899; GO:0060112; GO:0070373; GO:0070374; GO:0080164; GO:0095500; GO:0097061; GO:0097110; GO:0098690; GO:0098793; GO:0098815; GO:0098897; GO:0098981; GO:0099171; GO:0099634; GO:0140059; GO:1900273; GO:1901214; GO:1902004; GO:1904315; GO:1904645; GO:1905144; GO:1905906; GO:1905920; GO:1905923; GO:2000463; GO:2001023 37019 XR_006394540.1 420 468 326 531 263 NA NA NA NA NA NA 37020 XM_044307433.1 291 420 126 80 237 Q9VFB2 3.35e-35 28S ribosomal protein S10, mitochondrial (MRP-S10) (S10mt) Drosophila melanogaster (Fruit fly) mitochondrial translation [GO:0032543] GO:0003735; GO:0005739; GO:0005763; GO:0032543 37021 XR_003827390.2 29 0 4 21 5 NA NA NA NA NA NA 37022 XM_044318476.1 1271 708 353 998 656 P29294 1.62e-85 Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form] Oryctolagus cuniculus (Rabbit) protein phosphorylation [GO:0006468] GO:0003779; GO:0004687; GO:0005516; GO:0005524; GO:0005737; GO:0005856; GO:0006468; GO:0030027; GO:0032154; GO:0046872 37023 XM_044318476.1 1271 708 353 998 656 P29294 5.59e-62 Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form] Oryctolagus cuniculus (Rabbit) protein phosphorylation [GO:0006468] GO:0003779; GO:0004687; GO:0005516; GO:0005524; GO:0005737; GO:0005856; GO:0006468; GO:0030027; GO:0032154; GO:0046872 37024 XM_029332053.2 0 0 0 0 396 Q5R4U9 9.56e-82 Sorcin Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) calcium ion transport [GO:0006816]; cytoplasmic sequestering of transcription factor [GO:0042994]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of heart rate [GO:0010459]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of relaxation of muscle [GO:1901077] GO:0002020; GO:0005509; GO:0005654; GO:0005829; GO:0005886; GO:0006816; GO:0010459; GO:0030018; GO:0033017; GO:0035774; GO:0042584; GO:0042994; GO:0046982; GO:0051281; GO:0055118; GO:0060315; GO:0070062; GO:0086004; GO:0140297; GO:1901077; GO:1901841; GO:1901844; GO:2000678 37025 XM_029339771.2 51 93 27 0 133 NA NA NA NA NA NA 37026 XM_044325301.1 0 0 0 0 6 NA NA NA NA NA NA 37027 XM_029336130.2 860 632 732 798 1401 Q3UDK1 3.53e-34 TRAF-type zinc finger domain-containing protein 1 (Protein FLN29) Mus musculus (Mouse) negative regulation of innate immune response [GO:0045824] GO:0008270; GO:0045824 37028 XM_044314242.1 252 50 113 0 180 NA NA NA NA NA NA 37029 XM_044312272.1 96 0 13 0 0 O00463 2.25e-22 TNF receptor-associated factor 5 (RING finger protein 84) Homo sapiens (Human) apoptotic process [GO:0006915]; interleukin-17-mediated signaling pathway [GO:0097400]; mRNA stabilization [GO:0048255]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of JNK cascade [GO:0046330]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; signal transduction [GO:0007165]; signal transduction involved in regulation of gene expression [GO:0023019]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0005164; GO:0005813; GO:0005829; GO:0006915; GO:0007165; GO:0008270; GO:0008284; GO:0009898; GO:0023019; GO:0031625; GO:0031996; GO:0033209; GO:0035631; GO:0042802; GO:0042981; GO:0043122; GO:0043123; GO:0046330; GO:0048255; GO:0051091; GO:0051092; GO:0070534; GO:0097400 37030 XM_044310668.1 14 0 16 0 3 NA NA NA NA NA NA 37031 XM_029338826.2 335 205 178 191 527 P97479 0 Unconventional myosin-VIIa Mus musculus (Mouse) actin filament organization [GO:0007015]; actin filament-based movement [GO:0030048]; auditory receptor cell stereocilium organization [GO:0060088]; cell projection organization [GO:0030030]; equilibrioception [GO:0050957]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear development [GO:0048839]; inner ear morphogenesis [GO:0042472]; inner ear receptor cell differentiation [GO:0060113]; inner ear receptor cell stereocilium organization [GO:0060122]; intracellular protein transport [GO:0006886]; lysosome organization [GO:0007040]; mechanoreceptor differentiation [GO:0042490]; phagocytosis [GO:0006909]; phagolysosome assembly [GO:0001845]; pigment granule localization [GO:0051875]; pigment granule transport [GO:0051904]; post-embryonic animal organ morphogenesis [GO:0048563]; protein localization [GO:0008104]; sensory organ development [GO:0007423]; sensory perception [GO:0007600]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; vesicle transport along actin filament [GO:0030050]; visual perception [GO:0007601] GO:0000146; GO:0001750; GO:0001845; GO:0001917; GO:0003774; GO:0003779; GO:0005516; GO:0005524; GO:0005737; GO:0005765; GO:0005829; GO:0005902; GO:0005938; GO:0006886; GO:0006909; GO:0007015; GO:0007040; GO:0007423; GO:0007600; GO:0007601; GO:0007605; GO:0008104; GO:0015629; GO:0016324; GO:0016459; GO:0019904; GO:0030030; GO:0030048; GO:0030050; GO:0030507; GO:0031477; GO:0031982; GO:0032391; GO:0032420; GO:0042470; GO:0042472; GO:0042490; GO:0042491; GO:0042802; GO:0043531; GO:0044877; GO:0045202; GO:0047485; GO:0048563; GO:0048839; GO:0050953; GO:0050957; GO:0051015; GO:0051875; GO:0051904; GO:0060088; GO:0060113; GO:0060122; GO:0120044; GO:1990435 37032 XM_029358586.2 2614 1653 1014 1477 1447 Q6DIJ4 6.37e-109 Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.4.19.12) (Deubiquitinating enzyme 10) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) autophagy [GO:0006914]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to interleukin-1 [GO:0071347]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA repair [GO:0006281]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; protein deubiquitination [GO:0016579]; regulation of autophagy [GO:0010506]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0002039; GO:0004197; GO:0004843; GO:0005634; GO:0005737; GO:0005769; GO:0006281; GO:0006511; GO:0006914; GO:0006974; GO:0010506; GO:0016579; GO:0030330; GO:0043124; GO:0044325; GO:0071347 37033 XR_006395751.1 111 29 37 1 2 NA NA NA NA NA NA 37034 XM_044329054.1 27 12 23 18 27 Q09575 8.34e-24 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 37035 XM_044314780.1 77 0 0 17 16 NA NA NA NA NA NA 37036 XM_029348460.2 396 265 22 97 34 Q53HC5 4.63e-41 Kelch-like protein 26 Homo sapiens (Human) NA NA 37037 XM_044314535.1 143 114 28 167 144 NA NA NA NA NA NA 37038 XM_044314787.1 67 160 98 670 49 NA NA NA NA NA NA 37039 XM_029323594.2 423 330 400 566 721 P51400 5.95e-166 Double-stranded RNA-specific editase 1 (EC 3.5.4.37) (RNA-editing deaminase 1) (RNA-editing enzyme 1) (dsRNA adenosine deaminase) Rattus norvegicus (Rat) adenosine to inosine editing [GO:0006382]; base conversion or substitution editing [GO:0016553]; brain development [GO:0007420]; facial nerve morphogenesis [GO:0021610]; hypoglossal nerve morphogenesis [GO:0021618]; innervation [GO:0060384]; motor behavior [GO:0061744]; motor neuron apoptotic process [GO:0097049]; mRNA modification [GO:0016556]; mRNA processing [GO:0006397]; multicellular organism growth [GO:0035264]; muscle tissue morphogenesis [GO:0060415]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; neuromuscular process controlling posture [GO:0050884]; neuromuscular synaptic transmission [GO:0007274]; positive regulation of mRNA processing [GO:0050685]; positive regulation of viral genome replication [GO:0045070]; regulation of cell cycle [GO:0051726]; RNA processing [GO:0006396]; spinal cord ventral commissure morphogenesis [GO:0021965] GO:0003723; GO:0003725; GO:0003726; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0006382; GO:0006396; GO:0006397; GO:0007274; GO:0007420; GO:0008251; GO:0008285; GO:0016553; GO:0016556; GO:0021610; GO:0021618; GO:0021965; GO:0030336; GO:0035264; GO:0042802; GO:0044387; GO:0045070; GO:0045202; GO:0046872; GO:0050685; GO:0050884; GO:0051726; GO:0060384; GO:0060415; GO:0061744; GO:0097049 37040 XM_029349806.2 477 458 365 421 502 Q4KLV7 1.88e-132 Protein FAM50A-B Xenopus laevis (African clawed frog) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0005634; GO:0006397; GO:0008380 37041 XM_029356191.2 800 633 541 539 220 Q6MG12 4.5e-24 Uncharacterized protein C6orf136 homolog Rattus norvegicus (Rat) NA NA 37042 XM_044310171.1 0 0 0 0 16 Q9D662 4.78e-140 Protein transport protein Sec23B (SEC23-related protein B) Mus musculus (Mouse) COPII-coated vesicle cargo loading [GO:0090110]; intracellular protein transport [GO:0006886] GO:0005096; GO:0005783; GO:0005789; GO:0005829; GO:0006886; GO:0008270; GO:0012505; GO:0030127; GO:0048471; GO:0070971; GO:0090110 37043 XM_029352258.2 522 627 238 843 628 Q6GQ33 4.54e-63 Calmodulin-lysine N-methyltransferase (CLNMT) (CaM KMT) (EC 2.1.1.60) Xenopus laevis (African clawed frog) NA GO:0005634; GO:0005737; GO:0018025 37044 XM_044306809.1 6 3 5 9 6 NA NA NA NA NA NA 37045 XM_029340701.2 5869 6714 3965 4701 4487 Q9CR47 2.37e-157 Ribosome biogenesis protein NSA2 homolog (L-name-related protein 42) (LNR42) (TGF-beta-inducible nuclear protein 1) Mus musculus (Mouse) maturation of 5.8S rRNA [GO:0000460]; maturation of LSU-rRNA [GO:0000470] GO:0000460; GO:0000470; GO:0005730; GO:0030687 37046 XM_029337151.2 10 10 5 67 20 NA NA NA NA NA NA 37047 XM_029330255.2 3566 3487 2475 3946 2997 B5DGI7 8.11e-56 RNA-binding protein 8A (RNA-binding motif protein 8A) (Ribonucleoprotein RBM8A) Salmo salar (Atlantic salmon) mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of translation [GO:0006417] GO:0000184; GO:0000381; GO:0000398; GO:0003729; GO:0005634; GO:0005737; GO:0006417; GO:0016607; GO:0051028; GO:0071006 37048 XM_029340113.2 557 490 278 412 157 O97860 9.94e-75 Tartrate-resistant acid phosphatase type 5 (TR-AP) (EC 3.1.3.2) (Tartrate-resistant acid ATPase) (TrATPase) (Type 5 acid phosphatase) Oryctolagus cuniculus (Rabbit) NA GO:0003993; GO:0005764; GO:0008198; GO:0008199 37049 XM_029324145.2 11040 9728 3998 7560 10176 Q6NYB7 6.87e-123 Ras-related protein Rab-1A (EC 3.6.5.2) Rattus norvegicus (Rat) autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; cell migration [GO:0016477]; COPII-coated vesicle cargo loading [GO:0090110]; defense response to bacterium [GO:0042742]; endocytosis [GO:0006897]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; growth hormone secretion [GO:0030252]; intracellular protein transport [GO:0006886]; melanosome transport [GO:0032402]; positive regulation of glycoprotein metabolic process [GO:1903020]; positive regulation of interleukin-8 production [GO:0032757]; Rab protein signal transduction [GO:0032482]; substrate adhesion-dependent cell spreading [GO:0034446]; vesicle transport along microtubule [GO:0047496]; virion assembly [GO:0019068] GO:0000045; GO:0000139; GO:0003924; GO:0003925; GO:0005525; GO:0005769; GO:0005789; GO:0005794; GO:0005829; GO:0006886; GO:0006888; GO:0006897; GO:0006914; GO:0007030; GO:0012505; GO:0016477; GO:0019068; GO:0030252; GO:0032402; GO:0032482; GO:0032757; GO:0034446; GO:0042470; GO:0042742; GO:0043025; GO:0047496; GO:0090110; GO:0098793; GO:1903020 37050 XR_006392383.1 708 1411 585 1753 832 P13595 3.35e-39 Neural cell adhesion molecule 1 (N-CAM-1) (NCAM-1) (CD antigen CD56) Mus musculus (Mouse) aging [GO:0007568]; axonal fasciculation [GO:0007413]; calcium-mediated signaling [GO:0019722]; cell surface receptor signaling pathway [GO:0007166]; commissural neuron axon guidance [GO:0071679]; homotypic cell-cell adhesion [GO:0034109]; learning or memory [GO:0007611]; modulation of chemical synaptic transmission [GO:0050804]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell death [GO:0060548]; neuron development [GO:0048666]; neuron projection development [GO:0031175]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; regulation of exocyst assembly [GO:0001928]; regulation of semaphorin-plexin signaling pathway [GO:2001260]; regulation of sensory perception of pain [GO:0051930]; response to cocaine [GO:0042220]; response to lead ion [GO:0010288]; response to xenobiotic stimulus [GO:0009410]; thalamus development [GO:0021794] GO:0001928; GO:0005829; GO:0005886; GO:0005911; GO:0007166; GO:0007413; GO:0007568; GO:0007611; GO:0008201; GO:0009410; GO:0009897; GO:0009986; GO:0010288; GO:0019722; GO:0019902; GO:0021794; GO:0030275; GO:0030424; GO:0030426; GO:0031175; GO:0033555; GO:0034109; GO:0042220; GO:0042734; GO:0043005; GO:0043025; GO:0043209; GO:0045211; GO:0048666; GO:0050804; GO:0050850; GO:0051930; GO:0060045; GO:0060548; GO:0071679; GO:0098685; GO:0098978; GO:2001260 37051 XM_029335130.2 2559 1176 716 2986 1673 Q4R7U0 5.11e-111 Transmembrane channel-like protein 7 Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) ion transport [GO:0006811] GO:0005886; GO:0006811 37052 XM_044327494.1 0 279 348 563 0 NA NA NA NA NA NA 37053 XM_029350717.2 958 860 694 390 659 O14653 1.59e-58 Golgi SNAP receptor complex member 2 (27 kDa Golgi SNARE protein) (Membrin) Homo sapiens (Human) intra-Golgi vesicle-mediated transport [GO:0006891]; protein transport [GO:0015031]; vesicle fusion [GO:0006906] GO:0000139; GO:0000149; GO:0005484; GO:0005789; GO:0005794; GO:0006891; GO:0006906; GO:0012507; GO:0015031; GO:0016020; GO:0031201; GO:0031902; GO:0033116 37054 XM_044314276.1 9 8 1 10 9 NA NA NA NA NA NA 37055 XM_029351741.2 8229 4178 5378 1680 1523 P17244 0 Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (EC 1.2.1.12) (Peptidyl-cysteine S-nitrosylase GAPDH) (EC 2.6.99.-) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]; innate immune response [GO:0045087]; microtubule cytoskeleton organization [GO:0000226]; neuron apoptotic process [GO:0051402]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of type I interferon production [GO:0032481]; protein stabilization [GO:0050821]; regulation of translation [GO:0006417] GO:0000226; GO:0004365; GO:0005634; GO:0005737; GO:0005829; GO:0006006; GO:0006096; GO:0006417; GO:0008017; GO:0015630; GO:0032481; GO:0035605; GO:0035606; GO:0043123; GO:0045087; GO:0050661; GO:0050821; GO:0051287; GO:0051402; GO:0097452 37056 XM_029345036.2 7961 9959 3853 8027 5943 NA NA NA NA NA NA 37057 XM_044319894.1 83 92 31 96 111 Q9N294 1.81e-32 Beta-1,3-galactosyltransferase 5 (Beta-1,3-GalTase 5) (Beta3Gal-T5) (Beta3GalT5) (b3Gal-T5) (EC 2.4.1.-) (Beta-3-Gx-T5) (UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 5) (UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 5) Pan paniscus (Pygmy chimpanzee) (Bonobo) lipid metabolic process [GO:0006629]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0006629; GO:0016758 37058 XM_044311416.1 107 9 42 55 38 Q9CL21 4.51e-30 ATP-dependent DNA helicase RecQ (EC 3.6.4.12) Pasteurella multocida (strain Pm70) DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; SOS response [GO:0009432] GO:0003677; GO:0005524; GO:0006260; GO:0006281; GO:0006310; GO:0009432; GO:0016887; GO:0043138 37059 XM_044307805.1 3 0 0 0 25 P0DP43 1.34e-37 Cation channel sperm-associated auxiliary subunit epsilon (CatSper-epsilon) (CatSperepsilon) (C1orf101-like protein) Mus musculus (Mouse) flagellated sperm motility [GO:0030317]; sperm capacitation [GO:0048240] GO:0030317; GO:0036128; GO:0048240; GO:0097228 37060 XM_029330581.2 2512 2119 1568 2416 1860 Q38SD2 0 Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1) Homo sapiens (Human) bone resorption [GO:0045453]; intracellular signal transduction [GO:0035556]; negative regulation of peptidyl-tyrosine phosphorylation [GO:0050732]; osteoclast development [GO:0036035]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; signal transduction [GO:0007165] GO:0004674; GO:0004722; GO:0005524; GO:0005525; GO:0005737; GO:0005739; GO:0005829; GO:0007165; GO:0018108; GO:0035556; GO:0036035; GO:0042802; GO:0043231; GO:0045453; GO:0046872; GO:0050731; GO:0050732; GO:0090263; GO:0106310; GO:1902533 37061 XM_044327194.1 0 0 35 0 243 NA NA NA NA NA NA 37062 XM_044322420.1 4233 6016 4075 4226 2572 NA NA NA NA NA NA 37063 XM_029354545.2 1 0 15 14 34 NA NA NA NA NA NA 37064 XM_044320229.1 1092 779 628 676 992 Q96AG4 3.27e-44 Leucine-rich repeat-containing protein 59 (Ribosome-binding protein p34) (p34) [Cleaved into: Leucine-rich repeat-containing protein 59, N-terminally processed] Homo sapiens (Human) positive regulation of Ras protein signal transduction [GO:0046579]; signal transduction [GO:0007165] GO:0003723; GO:0005635; GO:0005783; GO:0005789; GO:0007165; GO:0016020; GO:0042645; GO:0045296; GO:0046579 37065 XM_044313382.1 9 0 13 4 192 NA NA NA NA NA NA 37066 XM_044326617.1 0 0 0 6 3 NA NA NA NA NA NA 37067 XM_029327180.2 101 85 73 525 151 NA NA NA NA NA NA 37068 XM_029352246.2 2018 1299 356 1001 854 NA NA NA NA NA NA 37069 XM_044322976.1 789 238 418 557 1076 Q838D6 1.87e-43 L-tyrosine decarboxylase (TDC) (EC 4.1.1.25) (Levodopa decarboxylase) (L-dopa decarboxylase) (EC 4.1.1.-) Enterococcus faecalis (strain ATCC 700802 / V583) L-dopa metabolic process [GO:1903184] GO:0004837; GO:0030170; GO:0036468; GO:1903184 37070 XM_044326300.1 169 115 64 149 56 Q5VU97 6.15e-85 VWFA and cache domain-containing protein 1 (Cache domain-containing protein 1) Homo sapiens (Human) NA GO:0005245; GO:0005891 37071 XM_044324691.1 2389 0 0 5 0 D3YXG0 3.53e-45 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 37072 XM_044324691.1 2389 0 0 5 0 D3YXG0 5.48e-43 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 37073 XM_044324691.1 2389 0 0 5 0 D3YXG0 3.9e-42 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 37074 XM_044324691.1 2389 0 0 5 0 D3YXG0 1.5e-39 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 37075 XM_044324691.1 2389 0 0 5 0 D3YXG0 6.48e-39 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 37076 XM_044324691.1 2389 0 0 5 0 D3YXG0 1.5e-38 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 37077 XM_044324691.1 2389 0 0 5 0 D3YXG0 1.99e-38 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 37078 XM_044324691.1 2389 0 0 5 0 D3YXG0 1.75e-37 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 37079 XM_044324691.1 2389 0 0 5 0 D3YXG0 1.9e-37 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 37080 XM_044324691.1 2389 0 0 5 0 D3YXG0 6.05e-36 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 37081 XM_044324691.1 2389 0 0 5 0 D3YXG0 3.63e-35 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 37082 XM_044324691.1 2389 0 0 5 0 D3YXG0 7.72e-35 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 37083 XM_044324691.1 2389 0 0 5 0 D3YXG0 4.71e-34 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 37084 XM_044324691.1 2389 0 0 5 0 D3YXG0 5.21e-25 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 37085 XM_029340975.2 316 399 168 268 321 O95619 4.99e-87 YEATS domain-containing protein 4 (Glioma-amplified sequence 41) (Gas41) (NuMA-binding protein 1) (NuBI-1) (NuBI1) Homo sapiens (Human) chromatin remodeling [GO:0006338]; histone acetylation [GO:0016573]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; mitotic cell cycle [GO:0000278]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of DNA-templated transcription [GO:0006355]; regulation of double-strand break repair [GO:2000779]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000278; GO:0000786; GO:0005200; GO:0005634; GO:0005654; GO:0006338; GO:0006355; GO:0006357; GO:0008022; GO:0016363; GO:0016573; GO:0031965; GO:0035267; GO:0042393; GO:0042981; GO:0043967; GO:0043968; GO:0045893; GO:0051726; GO:0070577; GO:0140030; GO:1905168; GO:2000779 37086 XR_003824548.2 76 86 12 16 10 NA NA NA NA NA NA 37087 XM_044312985.1 0 96 155 121 179 B7ZCC9 1.07e-47 Adhesion G-protein coupled receptor G4 (G-protein coupled receptor 112) Mus musculus (Mouse) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; neurogenesis [GO:0022008] GO:0004930; GO:0005886; GO:0007166; GO:0007189; GO:0022008 37088 XM_044309755.1 139 106 169 164 258 O75581 0 Low-density lipoprotein receptor-related protein 6 (LRP-6) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; chemical synaptic transmission [GO:0007268]; dopaminergic neuron differentiation [GO:0071542]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001933; GO:0005041; GO:0005102; GO:0005109; GO:0005576; GO:0005783; GO:0005886; GO:0006469; GO:0007204; GO:0007268; GO:0009986; GO:0014029; GO:0014033; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0031410; GO:0031901; GO:0034392; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043434; GO:0044335; GO:0044340; GO:0045121; GO:0045202; GO:0045787; GO:0045893; GO:0045944; GO:0051091; GO:0060070; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072659; GO:0090118; GO:0090244; GO:0098609; GO:1904928; GO:1904948; GO:1904953; GO:1990851; GO:1990909 37089 XM_044309755.1 139 106 169 164 258 O75581 1.78e-169 Low-density lipoprotein receptor-related protein 6 (LRP-6) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; chemical synaptic transmission [GO:0007268]; dopaminergic neuron differentiation [GO:0071542]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001933; GO:0005041; GO:0005102; GO:0005109; GO:0005576; GO:0005783; GO:0005886; GO:0006469; GO:0007204; GO:0007268; GO:0009986; GO:0014029; GO:0014033; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0031410; GO:0031901; GO:0034392; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043434; GO:0044335; GO:0044340; GO:0045121; GO:0045202; GO:0045787; GO:0045893; GO:0045944; GO:0051091; GO:0060070; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072659; GO:0090118; GO:0090244; GO:0098609; GO:1904928; GO:1904948; GO:1904953; GO:1990851; GO:1990909 37090 XM_029356343.2 12 1013 6 15 14 Q8CIQ7 0 Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP) Mus musculus (Mouse) small GTPase mediated signal transduction [GO:0007264] GO:0005085; GO:0005096; GO:0005737; GO:0005829; GO:0005886; GO:0007264; GO:0017124; GO:0031267 37091 XM_029346448.2 1052 428 215 292 204 Q9SY73 9.37e-64 NADPH-dependent pterin aldehyde reductase (EC 1.1.1.-) Arabidopsis thaliana (Mouse-ear cress) folic acid-containing compound metabolic process [GO:0006760] GO:0005829; GO:0006760; GO:0016616 37092 XM_044326737.1 63 0 0 43 129 NA NA NA NA NA NA 37093 XM_044312426.1 0 16 0 42 0 NA NA NA NA NA NA 37094 XM_044317767.1 12 24 0 0 7 Q9BTY7 1.73e-27 Protein HGH1 homolog Homo sapiens (Human) NA NA 37095 XM_029328139.2 83 0 2 12 0 NA NA NA NA NA NA 37096 XR_006391893.1 70 0 12 0 2 NA NA NA NA NA NA 37097 XR_006396682.1 5 2 0 7 21 NA NA NA NA NA NA 37098 XM_044312026.1 0 27 4 25 9 NA NA NA NA NA NA 37099 XM_044315623.1 2 6 0 0 4 NA NA NA NA NA NA 37100 XM_029323521.2 0 34 0 0 123 A2RU49 1.43e-50 Hydroxylysine kinase (5-hydroxy-L-lysine kinase) (EC 2.7.1.81) (Aminoglycoside phosphotransferase domain-containing protein 1) Homo sapiens (Human) lysine catabolic process [GO:0006554]; phosphorylation [GO:0016310] GO:0005759; GO:0006554; GO:0016310; GO:0019202; GO:0047992 37101 XM_044325655.1 2 6 0 13 29 NA NA NA NA NA NA 37102 XM_029336916.2 214 234 247 320 157 NA NA NA NA NA NA 37103 XM_029353762.2 387 0 22 645 1045 NA NA NA NA NA NA 37104 XM_044322756.1 1146 915 50 399 1265 Q8LQJ9 0 ATP-dependent zinc metalloprotease FTSH 4, mitochondrial (OsFTSH4) (EC 3.4.24.-) Oryza sativa subsp. japonica (Rice) proteolysis [GO:0006508] GO:0004176; GO:0004222; GO:0005524; GO:0005739; GO:0006508; GO:0009534; GO:0016020; GO:0016887; GO:0046872 37105 XM_044329341.1 749 746 696 815 607 Q21279 3.14e-104 Probable tubulin polyglutamylase ttll-15 (EC 6.-.-.-) (Tubulin--tyrosine ligase-like protein 15) Caenorhabditis elegans oviposition [GO:0018991]; protein modification process [GO:0036211] GO:0005524; GO:0016874; GO:0018991; GO:0036211 37106 XM_044316970.1 118 78 50 193 62 Q96K80 2.79e-31 Zinc finger CCCH domain-containing protein 10 Homo sapiens (Human) negative regulation of miRNA maturation [GO:1903799]; post-transcriptional regulation of gene expression [GO:0010608]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381] GO:0000381; GO:0003723; GO:0005654; GO:0005737; GO:0010608; GO:0035198; GO:0046872; GO:1903799 37107 XR_006395225.1 8 0 0 0 10 NA NA NA NA NA NA 37108 XM_029331794.2 1326 1487 744 1135 1030 NA NA NA NA NA NA 37109 XM_044311132.1 196 114 167 196 214 NA NA NA NA NA NA 37110 XM_029324183.2 88 59 36 135 73 Q3B8H4 8.47e-62 Rhombotin-1 (LIM domain only protein 1) (LMO-1) Xenopus laevis (African clawed frog) NA GO:0005634; GO:0046872 37111 XR_003826503.2 212 265 220 198 147 NA NA NA NA NA NA 37112 XM_044320215.1 706 1387 545 216 883 NA NA NA NA NA NA 37113 XM_044309381.1 0 11 0 135 32 NA NA NA NA NA NA 37114 XM_044319567.1 15 0 4 4 27 NA NA NA NA NA NA 37115 XM_044312577.1 55 0 15 54 69 Q80U62 1.67e-68 Run domain Beclin-1-interacting and cysteine-rich domain-containing protein (Rubicon) Mus musculus (Mouse) autophagy [GO:0006914]; endocytosis [GO:0006897]; immune system process [GO:0002376]; negative regulation of autophagosome maturation [GO:1901097]; negative regulation of autophagy [GO:0010507]; negative regulation of endocytosis [GO:0045806]; negative regulation of phosphatidylinositol 3-kinase activity [GO:0043553] GO:0002376; GO:0005654; GO:0005764; GO:0005769; GO:0005770; GO:0005829; GO:0006897; GO:0006914; GO:0010507; GO:0043231; GO:0043553; GO:0045806; GO:1901097; GO:1901981 37116 XR_003824945.2 200 266 118 137 158 NA NA NA NA NA NA 37117 XM_029358048.2 1428 1061 660 864 582 NA NA NA NA NA NA 37118 XM_044310315.1 115 9 73 60 550 Q80XJ3 4.24e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 37119 XM_029331269.2 681 277 394 441 472 Q92562 0 Polyphosphoinositide phosphatase (EC 3.1.3.-) (EC 3.1.3.36) (EC 3.1.3.86) (Phosphatidylinositol 3,5-bisphosphate 5-phosphatase) (SAC domain-containing protein 3) (Serine-protein phosphatase FIG4) (EC 3.1.3.16) Homo sapiens (Human) locomotory behavior [GO:0007626]; myelin assembly [GO:0032288]; negative regulation of myelination [GO:0031642]; neuron development [GO:0048666]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; pigmentation [GO:0043473]; positive regulation of neuron projection development [GO:0010976]; vacuole organization [GO:0007033] GO:0000139; GO:0004438; GO:0004439; GO:0004722; GO:0005783; GO:0005811; GO:0006661; GO:0007033; GO:0007626; GO:0010008; GO:0010976; GO:0031642; GO:0031901; GO:0031902; GO:0032288; GO:0034485; GO:0043231; GO:0043473; GO:0043812; GO:0043813; GO:0046856; GO:0048666; GO:0055037 37120 XM_029331269.2 681 277 394 441 472 Q92562 6.72e-59 Polyphosphoinositide phosphatase (EC 3.1.3.-) (EC 3.1.3.36) (EC 3.1.3.86) (Phosphatidylinositol 3,5-bisphosphate 5-phosphatase) (SAC domain-containing protein 3) (Serine-protein phosphatase FIG4) (EC 3.1.3.16) Homo sapiens (Human) locomotory behavior [GO:0007626]; myelin assembly [GO:0032288]; negative regulation of myelination [GO:0031642]; neuron development [GO:0048666]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; pigmentation [GO:0043473]; positive regulation of neuron projection development [GO:0010976]; vacuole organization [GO:0007033] GO:0000139; GO:0004438; GO:0004439; GO:0004722; GO:0005783; GO:0005811; GO:0006661; GO:0007033; GO:0007626; GO:0010008; GO:0010976; GO:0031642; GO:0031901; GO:0031902; GO:0032288; GO:0034485; GO:0043231; GO:0043473; GO:0043812; GO:0043813; GO:0046856; GO:0048666; GO:0055037 37121 XM_044318747.1 41 25 81 63 198 Q766D5 3.15e-60 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Mus musculus (Mouse) chondroitin sulfate biosynthetic process [GO:0030206] GO:0008376; GO:0030206; GO:0032580; GO:0033842; GO:0047238 37122 XM_029336558.2 0 129 223 242 270 Q29496 9.62e-107 Cytochrome P450 3A24 (EC 1.14.14.1) (CYPIIIA24) Ovis aries (Sheep) NA GO:0004497; GO:0005506; GO:0005789; GO:0020037; GO:0070330 37123 XR_003826244.2 423 308 292 15 114 NA NA NA NA NA NA 37124 XM_029334935.2 289 117 0 0 0 Q9NRA8 1.31e-32 Eukaryotic translation initiation factor 4E transporter (4E-T) (eIF4E transporter) (Eukaryotic translation initiation factor 4E nuclear import factor 1) Homo sapiens (Human) miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; mRNA stabilization [GO:0048255]; negative regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0106289]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of translation [GO:0017148]; neuron differentiation [GO:0030182]; P-body assembly [GO:0033962]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; protein import into nucleus [GO:0006606]; stem cell population maintenance [GO:0019827]; translation [GO:0006412] GO:0000932; GO:0003723; GO:0003729; GO:0005049; GO:0005634; GO:0005737; GO:0005829; GO:0006412; GO:0006606; GO:0016020; GO:0016605; GO:0016607; GO:0017148; GO:0019827; GO:0019900; GO:0030182; GO:0033962; GO:0035278; GO:0043231; GO:0045665; GO:0048255; GO:0060213; GO:0106289 37125 XM_044327062.1 57 6 9 113 316 NA NA NA NA NA NA 37126 XM_044312109.1 10 2 0 5 0 Q09575 1.12e-49 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 37127 XM_044318128.1 37 5 25 28 24 NA NA NA NA NA NA 37128 XM_044312550.1 0 0 1 8 6 B8V7S0 1.18e-68 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 37129 XM_044310077.1 3 11 0 27 24 NA NA NA NA NA NA 37130 XM_029331157.2 4162 5139 3362 9751 8029 P53111 4.62e-35 NADPH-dependent aldehyde reductase ARI1 (EC 1.1.1.-) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) NA GO:0004090; GO:0005634; GO:0005737; GO:0016491; GO:0016616 37131 XM_029352655.2 11 7 7 2 21 NA NA NA NA NA NA 37132 XM_044322572.1 7 0 4 0 0 NA NA NA NA NA NA 37133 XM_029324540.2 14 1 0 6 0 NA NA NA NA NA NA 37134 XM_044308412.1 19 29 38 56 28 O93403 1.88e-25 Carbohydrate sulfotransferase 3 (EC 2.8.2.17) (EC 2.8.2.21) (Chondroitin 6-O-sulfotransferase 1) (C6ST-1) (Nervous system involved sulfotransferase) Tetronarce californica (Pacific electric ray) (Torpedo californica) carbohydrate metabolic process [GO:0005975]; chondroitin sulfate biosynthetic process [GO:0030206] GO:0000139; GO:0005975; GO:0008459; GO:0030206 37135 XM_029340689.2 2350 2112 1594 2037 1645 A4FUY7 1.29e-60 Molybdopterin synthase catalytic subunit (EC 2.8.1.12) (Molybdenum cofactor synthesis protein 2 large subunit) (Molybdenum cofactor synthesis protein 2B) (MOCS2B) Bos taurus (Bovine) Mo-molybdopterin cofactor biosynthetic process [GO:0006777] GO:0005829; GO:0006777; GO:0016607; GO:0019008; GO:0030366 37136 XM_029352604.2 12 0 18 0 4 P48040 1.01e-24 Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor) Ovis aries (Sheep) NA GO:0005886; GO:0008502 37137 XR_006392619.1 216 126 65 150 113 NA NA NA NA NA NA 37138 XM_044326976.1 336 766 324 502 233 NA NA NA NA NA NA 37139 XM_044322531.1 44 2 4 0 7 NA NA NA NA NA NA 37140 XR_006392242.1 28 43 33 71 146 NA NA NA NA NA NA 37141 XR_006392911.1 41 2 25 5 151 NA NA NA NA NA NA 37142 XM_029327071.2 120 74 56 47 95 Q64264 2.29e-21 5-hydroxytryptamine receptor 1A (5-HT-1A) (5-HT1A) (Serotonin receptor 1A) Mus musculus (Mouse) adenylate cyclase-inhibiting serotonin receptor signaling pathway [GO:0007198]; behavioral fear response [GO:0001662]; chemical synaptic transmission [GO:0007268]; exploration behavior [GO:0035640]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of gamma-aminobutyric acid secretion [GO:0014053]; NMDA glutamate receptor clustering [GO:0097114]; positive regulation of microtubule depolymerization [GO:0031117]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of dopamine metabolic process [GO:0042053]; regulation of feeding behavior [GO:0060259]; regulation of hormone secretion [GO:0046883]; regulation of serotonin secretion [GO:0014062]; regulation of vasoconstriction [GO:0019229]; serotonin metabolic process [GO:0042428]; serotonin receptor signaling pathway [GO:0007210] GO:0001662; GO:0001965; GO:0004993; GO:0005102; GO:0005886; GO:0007186; GO:0007187; GO:0007198; GO:0007210; GO:0007214; GO:0007268; GO:0014053; GO:0014062; GO:0019229; GO:0030425; GO:0030594; GO:0031117; GO:0035640; GO:0042053; GO:0042428; GO:0042734; GO:0043025; GO:0043203; GO:0046883; GO:0051378; GO:0060259; GO:0090722; GO:0097114; GO:0098982; GO:0099171 37143 XM_044328360.1 0 198 58 0 172 P52701 0 DNA mismatch repair protein Msh6 (hMSH6) (G/T mismatch-binding protein) (GTBP) (GTMBP) (MutS protein homolog 6) (MutS-alpha 160 kDa subunit) (p160) Homo sapiens (Human) determination of adult lifespan [GO:0008340]; DNA repair [GO:0006281]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; isotype switching [GO:0045190]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; negative regulation of DNA recombination [GO:0045910]; positive regulation of helicase activity [GO:0051096]; response to UV [GO:0009411]; somatic hypermutation of immunoglobulin genes [GO:0016446]; somatic recombination of immunoglobulin gene segments [GO:0016447]; spermatogenesis [GO:0007283] GO:0000710; GO:0000785; GO:0003682; GO:0003684; GO:0005524; GO:0005634; GO:0005654; GO:0005794; GO:0005829; GO:0006281; GO:0006298; GO:0007283; GO:0008094; GO:0008340; GO:0008630; GO:0009411; GO:0016446; GO:0016447; GO:0019899; GO:0030983; GO:0032137; GO:0032301; GO:0035064; GO:0043231; GO:0045190; GO:0045910; GO:0051096; GO:0097193; GO:0140664 37144 XM_029349974.2 8 0 56 0 0 NA NA NA NA NA NA 37145 XM_044321027.1 532 323 333 646 491 Q9UGM3 1.79e-62 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 37146 XM_044321027.1 532 323 333 646 491 Q9UGM3 1.7e-59 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 37147 XM_044321027.1 532 323 333 646 491 Q9UGM3 5.64e-59 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 37148 XM_044321027.1 532 323 333 646 491 Q9UGM3 7.19e-59 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 37149 XM_044321027.1 532 323 333 646 491 Q9UGM3 9.52e-59 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 37150 XM_044321027.1 532 323 333 646 491 Q9UGM3 2.76e-58 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 37151 XM_044321027.1 532 323 333 646 491 Q9UGM3 1.11e-57 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 37152 XM_044321027.1 532 323 333 646 491 Q9UGM3 1.36e-56 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 37153 XM_029347056.2 954 517 456 727 1099 NA NA NA NA NA NA 37154 XM_029339934.2 0 0 20 376 358 A0JM56 0 Leucine-rich repeat-containing protein 9 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737 37155 XR_006396087.1 1317 2544 874 3053 2308 NA NA NA NA NA NA 37156 XR_003824578.2 1605 2107 653 838 545 NA NA NA NA NA NA 37157 XM_044309850.1 673 431 308 636 469 Q9FT73 2.38e-30 ATP-dependent DNA helicase Q-like 2 (EC 3.6.4.12) (RecQ-like protein 2) (AtRQ2) (AtRecQ2) (AtRecQl2) Arabidopsis thaliana (Mouse-ear cress) DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724] GO:0000724; GO:0003677; GO:0005524; GO:0005694; GO:0005737; GO:0006268; GO:0006281; GO:0006310; GO:0009378; GO:0016592; GO:0016887; GO:0032508; GO:0043138; GO:0046872 37158 XM_029342159.2 7 22 0 44 28 NA NA NA NA NA NA 37159 XR_003825327.2 23 36 68 23 85 NA NA NA NA NA NA 37160 XR_003823475.1 48 40 41 61 60 NA NA NA NA NA NA 37161 XM_044326620.1 0 10 9 13 12 NA NA NA NA NA NA 37162 XM_044329295.1 92 0 8 0 0 P35234 2.44e-36 Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Neural-specific protein-tyrosine phosphatase) (Striatum-enriched protein-tyrosine phosphatase) (STEP) Rattus norvegicus (Rat) aging [GO:0007568]; exploration behavior [GO:0035640]; negative regulation of MAP kinase activity [GO:0043407]; peptidyl-tyrosine dephosphorylation [GO:0035335]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of receptor internalization [GO:0002092]; positive regulation of response to drug [GO:2001025]; protein dephosphorylation [GO:0006470]; response to acetylsalicylate [GO:1903492]; response to amphetamine [GO:0001975]; response to immobilization stress [GO:0035902]; response to xenobiotic stimulus [GO:0009410]; signal transduction [GO:0007165] GO:0001784; GO:0001934; GO:0001975; GO:0002092; GO:0004725; GO:0005783; GO:0005829; GO:0005886; GO:0006470; GO:0007165; GO:0007568; GO:0008021; GO:0009410; GO:0010976; GO:0016020; GO:0019901; GO:0030054; GO:0030424; GO:0035254; GO:0035335; GO:0035640; GO:0035902; GO:0042307; GO:0042802; GO:0043025; GO:0043204; GO:0043407; GO:0051019; GO:0097060; GO:1900273; GO:1901216; GO:1903492; GO:1903955; GO:1990635; GO:2001025 37163 XM_029356220.2 0 0 86 0 0 Q9JIM4 2.92e-66 Dual specificity protein phosphatase 12 (EC 3.1.3.16) (EC 3.1.3.48) (Glucokinase-associated dual specificity phosphatase) (GKAP) Rattus norvegicus (Rat) dephosphorylation [GO:0016311]; positive regulation of glucokinase activity [GO:0033133]; protein dephosphorylation [GO:0006470] GO:0004721; GO:0004725; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006470; GO:0008138; GO:0008270; GO:0016311; GO:0016791; GO:0017018; GO:0019900; GO:0033133 37164 XM_044322745.1 217 27 34 224 42 P95896 1.13e-141 Amidase (EC 3.5.1.4) Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) NA GO:0004040; GO:0043864 37165 XM_029325530.2 0 1 0 2 6 NA NA NA NA NA NA 37166 XR_006393351.1 224 113 126 178 144 NA NA NA NA NA NA 37167 XM_044328140.1 71 126 57 86 98 NA NA NA NA NA NA 37168 XM_029350342.2 244 85 100 440 72 NA NA NA NA NA NA 37169 XM_029349990.2 14 0 19 12 93 NA NA NA NA NA NA 37170 XM_029346835.2 0 9 19 18 0 P54357 3.63e-37 Myosin-2 essential light chain (Myosin II essential light chain) (Non-muscle myosin essential light chain) Drosophila melanogaster (Fruit fly) actin filament-based movement [GO:0030048] GO:0005509; GO:0005829; GO:0016460; GO:0017022; GO:0030048; GO:0031475; GO:0031476; GO:0031477; GO:0032036 37171 XM_044308318.1 724 510 341 641 466 Q95YJ5 0 Thioredoxin domain-containing protein 3 homolog (Dynein intermediate chain 3) Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis) cell differentiation [GO:0030154]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside diphosphate phosphorylation [GO:0006165]; spermatogenesis [GO:0007283]; UTP biosynthetic process [GO:0006228] GO:0004550; GO:0006165; GO:0006183; GO:0006228; GO:0006241; GO:0007283; GO:0030154 37172 XR_003825245.2 67 52 114 99 246 Q8IUH3 1.92e-92 RNA-binding protein 45 (Developmentally-regulated RNA-binding protein 1) (RB-1) (RNA-binding motif protein 45) Homo sapiens (Human) cell differentiation [GO:0030154]; nervous system development [GO:0007399] GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0007399; GO:0030154; GO:0042802; GO:1990904 37173 XM_044310654.1 8 4 0 0 42 NA NA NA NA NA NA 37174 XM_044317481.1 0 0 0 232 0 Q13114 5.66e-99 TNF receptor-associated factor 3 (EC 2.3.2.27) (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein 1) (LAP1) (RING-type E3 ubiquitin transferase TRAF3) Homo sapiens (Human) apoptotic process [GO:0006915]; defense response to virus [GO:0051607]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of JNK cascade [GO:0046330]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of cytokine production [GO:0001817]; regulation of defense response to virus [GO:0050688]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of interferon-beta production [GO:0032648]; regulation of proteolysis [GO:0030162]; signal transduction [GO:0007165]; Toll signaling pathway [GO:0008063]; toll-like receptor signaling pathway [GO:0002224]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; type I interferon-mediated signaling pathway [GO:0060337] GO:0000151; GO:0001817; GO:0002224; GO:0004842; GO:0005164; GO:0005739; GO:0005768; GO:0005829; GO:0006915; GO:0007165; GO:0008063; GO:0008270; GO:0009898; GO:0019901; GO:0019903; GO:0030162; GO:0031625; GO:0031996; GO:0032088; GO:0032648; GO:0033209; GO:0035631; GO:0035666; GO:0042802; GO:0042981; GO:0043122; GO:0046330; GO:0050688; GO:0051607; GO:0060337; GO:0070534; GO:1902554 37175 XR_006395944.1 0 10 0 0 31 NA NA NA NA NA NA 37176 XM_044323489.1 56 7 29 36 63 NA NA NA NA NA NA 37177 XM_044310690.1 0 0 0 1 24 NA NA NA NA NA NA 37178 XM_044309556.1 198 382 3 173 376 Q4A3R3 1.08e-55 Deleted in malignant brain tumors 1 protein (Hensin) Sus scrofa (Pig) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031]; zymogen activation [GO:0031638] GO:0004252; GO:0005044; GO:0005576; GO:0005886; GO:0015031; GO:0019898; GO:0030154; GO:0030658; GO:0031638; GO:0035375; GO:0042589; GO:0050829; GO:0050830 37179 XM_044309556.1 198 382 3 173 376 Q4A3R3 2.98e-55 Deleted in malignant brain tumors 1 protein (Hensin) Sus scrofa (Pig) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031]; zymogen activation [GO:0031638] GO:0004252; GO:0005044; GO:0005576; GO:0005886; GO:0015031; GO:0019898; GO:0030154; GO:0030658; GO:0031638; GO:0035375; GO:0042589; GO:0050829; GO:0050830 37180 XM_044309556.1 198 382 3 173 376 Q4A3R3 2.84e-28 Deleted in malignant brain tumors 1 protein (Hensin) Sus scrofa (Pig) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031]; zymogen activation [GO:0031638] GO:0004252; GO:0005044; GO:0005576; GO:0005886; GO:0015031; GO:0019898; GO:0030154; GO:0030658; GO:0031638; GO:0035375; GO:0042589; GO:0050829; GO:0050830 37181 XM_044309556.1 198 382 3 173 376 Q4A3R3 9.54e-26 Deleted in malignant brain tumors 1 protein (Hensin) Sus scrofa (Pig) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031]; zymogen activation [GO:0031638] GO:0004252; GO:0005044; GO:0005576; GO:0005886; GO:0015031; GO:0019898; GO:0030154; GO:0030658; GO:0031638; GO:0035375; GO:0042589; GO:0050829; GO:0050830 37182 XM_044309556.1 198 382 3 173 376 Q4A3R3 5.16e-23 Deleted in malignant brain tumors 1 protein (Hensin) Sus scrofa (Pig) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031]; zymogen activation [GO:0031638] GO:0004252; GO:0005044; GO:0005576; GO:0005886; GO:0015031; GO:0019898; GO:0030154; GO:0030658; GO:0031638; GO:0035375; GO:0042589; GO:0050829; GO:0050830 37183 XM_029338258.2 218 296 100 543 396 O15014 2.74e-22 Zinc finger protein 609 Homo sapiens (Human) muscle organ development [GO:0007517]; positive regulation of neuron migration [GO:2001224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of myoblast proliferation [GO:2000291]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0005634; GO:0005654; GO:0006357; GO:0007517; GO:0045944; GO:0046872; GO:1990841; GO:2000291; GO:2001224 37184 XM_044320218.1 1344 1469 635 826 411 NA NA NA NA NA NA 37185 XM_044323700.1 52 0 1 0 0 NA NA NA NA NA NA 37186 XM_044308588.1 1712 1076 963 1414 1802 Q9UNN5 5.38e-143 FAS-associated factor 1 (hFAF1) (UBX domain-containing protein 12) (UBX domain-containing protein 3A) Homo sapiens (Human) apoptotic process [GO:0006915]; cell death [GO:0008219]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell death [GO:0010942]; positive regulation of DNA replication [GO:0045740]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein-containing complex assembly [GO:0031334]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of cell adhesion [GO:0030155]; regulation of protein catabolic process [GO:0042176]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0005634; GO:0005635; GO:0005654; GO:0005783; GO:0005829; GO:0006915; GO:0007253; GO:0008219; GO:0010942; GO:0019887; GO:0019901; GO:0019904; GO:0030155; GO:0030433; GO:0031072; GO:0031265; GO:0031334; GO:0031625; GO:0034098; GO:0042176; GO:0043065; GO:0043130; GO:0043161; GO:0045732; GO:0045740; GO:0048471; GO:0051059; GO:1902043; GO:1990917 37187 XM_044308314.1 2239 2490 886 2156 2135 NA NA NA NA NA NA 37188 XM_029332796.2 531 440 322 352 358 Q9CZS3 5.05e-42 Centrosomal protein 20 (FGFR1OP N-terminal-like protein) (FOP-related protein of 20 kDa) (LisH domain-containing protein FOPNL) Mus musculus (Mouse) cilium assembly [GO:0060271]; microtubule anchoring [GO:0034453] GO:0005654; GO:0005737; GO:0005813; GO:0005814; GO:0031514; GO:0034451; GO:0034453; GO:0036064; GO:0042802; GO:0060271 37189 XR_006393406.1 35 44 41 52 104 NA NA NA NA NA NA 37190 XM_029358132.2 206 60 148 176 202 P49288 8.55e-28 Melatonin receptor type 1C (Mel-1C-R) (Mel1c receptor) (CKB) Gallus gallus (Chicken) G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of glucose import [GO:0046325]; negative regulation of glycolytic process [GO:0045820] GO:0004930; GO:0005654; GO:0005886; GO:0007186; GO:0008502; GO:0045820; GO:0046325; GO:1904408 37191 XM_044308920.1 0 0 0 9 0 NA NA NA NA NA NA 37192 XM_029358397.2 851 257 504 744 1160 Q60992 3.77e-171 Guanine nucleotide exchange factor VAV2 (VAV-2) Mus musculus (Mouse) angiogenesis [GO:0001525]; cell migration [GO:0016477]; cell projection assembly [GO:0030031]; lamellipodium assembly [GO:0030032]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; small GTPase mediated signal transduction [GO:0007264] GO:0001525; GO:0001784; GO:0005085; GO:0005154; GO:0005737; GO:0005829; GO:0005886; GO:0007264; GO:0008361; GO:0016477; GO:0030031; GO:0030032; GO:0043087; GO:0043552; GO:0046872 37193 XM_044322530.1 58 26 94 40 55 P54357 3.55e-40 Myosin-2 essential light chain (Myosin II essential light chain) (Non-muscle myosin essential light chain) Drosophila melanogaster (Fruit fly) actin filament-based movement [GO:0030048] GO:0005509; GO:0005829; GO:0016460; GO:0017022; GO:0030048; GO:0031475; GO:0031476; GO:0031477; GO:0032036 37194 XM_029349313.2 0 20 3 0 2 Q15075 2.59e-50 Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2) Homo sapiens (Human) chemical synaptic transmission, postsynaptic [GO:0099565]; early endosome to late endosome transport [GO:0045022]; endocytosis [GO:0006897]; modulation by host of viral process [GO:0044788]; synaptic vesicle to endosome fusion [GO:0016189]; vesicle fusion [GO:0006906] GO:0005516; GO:0005545; GO:0005737; GO:0005769; GO:0005829; GO:0005969; GO:0006897; GO:0006906; GO:0008270; GO:0016020; GO:0016189; GO:0019897; GO:0030742; GO:0031901; GO:0042803; GO:0044308; GO:0044788; GO:0045022; GO:0070062; GO:0098685; GO:0098794; GO:0098978; GO:0099565 37195 XM_044309296.1 18 0 0 0 78 NA NA NA NA NA NA 37196 XM_029356024.2 169 92 92 79 235 Q4KLQ5 1.21e-93 WD repeat-containing protein 76 Xenopus laevis (African clawed frog) NA NA 37197 XM_029355722.2 1066 673 362 371 234 Q0IH87 6.64e-84 Paired box protein Pax-3-B (xPax3-B) (Paired-domain transcription factor Pax3-B) Xenopus laevis (African clawed frog) fibroblast growth factor receptor signaling pathway [GO:0008543]; hatching gland development [GO:0048785]; nervous system development [GO:0007399]; neural crest cell fate commitment [GO:0014034]; neural crest formation [GO:0014029]; positive regulation of DNA-templated transcription [GO:0045893]; Wnt signaling pathway [GO:0016055] GO:0000981; GO:0003677; GO:0005634; GO:0007399; GO:0008543; GO:0014029; GO:0014034; GO:0016055; GO:0045893; GO:0048785 37198 XM_044311177.1 13 0 2 9 19 O60290 3.55e-27 Zinc finger protein 862 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006355; GO:0046872; GO:0046983 37199 XM_029353322.2 650 418 270 526 548 Q3UUG6 1.94e-56 TBC1 domain family member 24 Mus musculus (Mouse) axon development [GO:0061564]; dendrite development [GO:0016358]; negative regulation of oxidative stress-induced neuron death [GO:1903204]; negative regulation of peptidyl-cysteine S-nitrosylation [GO:1902083]; neuron death in response to oxidative stress [GO:0036475]; neuron projection development [GO:0031175]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neuron migration [GO:2001224]; synaptic vesicle endocytosis [GO:0048488] GO:0005096; GO:0005737; GO:0005886; GO:0016358; GO:0030054; GO:0030659; GO:0031175; GO:0031594; GO:0036475; GO:0043195; GO:0048488; GO:0050775; GO:0061564; GO:1902083; GO:1903204; GO:2000463; GO:2001224 37200 XM_029333536.2 4649 4327 2642 3484 2518 Q55E31 5.69e-74 Ras-related protein Rab-32B Dictyostelium discoideum (Social amoeba) intracellular protein transport [GO:0006886]; melanosome organization [GO:0032438]; vesicle-mediated transport [GO:0016192] GO:0003924; GO:0005525; GO:0005802; GO:0006886; GO:0012505; GO:0016192; GO:0031982; GO:0032438 37201 XM_044318478.1 40 20 74 193 168 O02827 2.76e-44 Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form] Ovis aries (Sheep) protein phosphorylation [GO:0006468] GO:0003779; GO:0004687; GO:0005516; GO:0005524; GO:0005737; GO:0005856; GO:0006468; GO:0030027; GO:0032154; GO:0046872 37202 XM_029357814.2 2 4 0 8 0 NA NA NA NA NA NA 37203 XR_006394669.1 92 41 71 145 34 NA NA NA NA NA NA 37204 XR_003825688.2 0 11 29 61 3 Q62717 0 Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1) (rCAPS) Rattus norvegicus (Rat) catecholamine secretion [GO:0050432]; establishment of localization in cell [GO:0051649]; exocytosis [GO:0006887]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of exocytosis [GO:0045921]; presynaptic dense core vesicle exocytosis [GO:0099525]; protein transport [GO:0015031]; regulated exocytosis [GO:0045055]; synaptic vesicle priming [GO:0016082]; vesicle organization [GO:0016050] GO:0005509; GO:0005546; GO:0006887; GO:0015031; GO:0016050; GO:0016082; GO:0019901; GO:0031045; GO:0031410; GO:0045055; GO:0045921; GO:0045956; GO:0050432; GO:0051649; GO:0098674; GO:0098793; GO:0098978; GO:0099525 37205 XM_029330221.2 41 10 15 24 11 Q9JHS6 2.8e-35 Acid-sensing ion channel 4 (ASIC4) (Amiloride-sensitive cation channel 4) (Spinal cord ASIC) Rattus norvegicus (Rat) behavioral fear response [GO:0001662]; sodium ion transmembrane transport [GO:0035725] GO:0001662; GO:0005886; GO:0015280; GO:0035725 37206 XR_003825094.2 556 657 548 649 528 NA NA NA NA NA NA 37207 XM_029327363.2 74 325 265 194 252 Q5ZL34 6.44e-36 Cleavage and polyadenylation specificity factor subunit 6 Gallus gallus (Chicken) messenger ribonucleoprotein complex assembly [GO:1990120]; mRNA alternative polyadenylation [GO:0110104]; positive regulation of RNA export from nucleus [GO:0046833]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; protein heterotetramerization [GO:0051290] GO:0003729; GO:0005634; GO:0005654; GO:0005726; GO:0005737; GO:0005847; GO:0005849; GO:0016607; GO:0035061; GO:0042382; GO:0046833; GO:0051290; GO:0098789; GO:0110104; GO:1990120 37208 XM_029327397.2 141 32 126 0 238 A1A5X5 1.67e-29 Adipolin (Adipose-derived insulin-sensitizing factor) (Complement C1q tumor necrosis factor-related protein 12) Danio rerio (Zebrafish) (Brachydanio rerio) regulation of glucose import [GO:0046324]; Wnt signaling pathway [GO:0016055] GO:0005179; GO:0005576; GO:0005615; GO:0016055; GO:0046324 37209 XM_044316409.1 119 132 103 75 14 NA NA NA NA NA NA 37210 XR_006395444.1 2 4 0 11 7 NA NA NA NA NA NA 37211 XM_044313785.1 106 144 118 99 79 NA NA NA NA NA NA 37212 XM_029330300.2 2485 2482 942 1372 2514 NA NA NA NA NA NA 37213 XM_029353521.2 0 0 2 0 9 NA NA NA NA NA NA 37214 XM_044313812.1 22 1 17 0 11 NA NA NA NA NA NA 37215 XM_044316978.1 130 84 6 18 6 NA NA NA NA NA NA 37216 XM_029343791.2 24610 40119 16609 15692 10178 NA NA NA NA NA NA 37217 XR_006391602.1 0 0 32 10 32 NA NA NA NA NA NA 37218 XM_044318708.1 334 76 53 279 214 P46825 1.44e-26 Kinesin light chain (KLC) Doryteuthis pealeii (Longfin inshore squid) (Loligo pealeii) NA GO:0005737; GO:0005871; GO:0005874 37219 XM_044318708.1 334 76 53 279 214 P46825 3.56e-23 Kinesin light chain (KLC) Doryteuthis pealeii (Longfin inshore squid) (Loligo pealeii) NA GO:0005737; GO:0005871; GO:0005874 37220 XM_044307220.1 172 10820 4346 8369 8332 NA NA NA NA NA NA 37221 XM_044312352.1 93 53 46 78 115 NA NA NA NA NA NA 37222 XR_003828410.2 42 37 47 67 58 NA NA NA NA NA NA 37223 XM_029330083.2 4365 4712 2972 6734 5719 P13195 0 5-aminolevulinate synthase, non-specific, mitochondrial (ALAS-H) (EC 2.3.1.37) (5-aminolevulinic acid synthase 1) (Delta-ALA synthase 1) (Delta-aminolevulinate synthase 1) Rattus norvegicus (Rat) cellular response to insulin stimulus [GO:0032869]; cellular response to organic cyclic compound [GO:0071407]; erythrocyte development [GO:0048821]; heme biosynthetic process [GO:0006783]; hemoglobin biosynthetic process [GO:0042541]; protoporphyrinogen IX biosynthetic process [GO:0006782]; response to bile acid [GO:1903412]; response to cAMP [GO:0051591]; response to cobalt ion [GO:0032025]; response to ethanol [GO:0045471]; response to gonadotropin [GO:0034698]; response to herbicide [GO:0009635]; response to hypoxia [GO:0001666]; response to nickel cation [GO:0010045]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to platinum ion [GO:0070541]; response to xenobiotic stimulus [GO:0009410] GO:0001666; GO:0003870; GO:0005739; GO:0005743; GO:0005759; GO:0006782; GO:0006783; GO:0009410; GO:0009635; GO:0010033; GO:0010045; GO:0014070; GO:0030170; GO:0031667; GO:0032025; GO:0032869; GO:0034698; GO:0042541; GO:0042802; GO:0045471; GO:0048821; GO:0051591; GO:0070541; GO:0071407; GO:1903412 37224 XM_044308222.1 1973 1477 1434 1922 2593 Q5W5U4 1.76e-161 Probable ATP-dependent RNA helicase DDX4 (EC 3.6.4.13) (DEAD box protein 4) Bos taurus (Bovine) cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; male meiosis I [GO:0007141]; male meiotic nuclear division [GO:0007140]; negative regulation of transposition [GO:0010529]; piRNA processing [GO:0034587]; spermatogenesis [GO:0007283] GO:0003676; GO:0003724; GO:0005524; GO:0005737; GO:0007140; GO:0007141; GO:0007283; GO:0010529; GO:0016887; GO:0030154; GO:0033391; GO:0034587; GO:0043046; GO:0048471; GO:0071546; GO:0071547 37225 XM_044315340.1 15 0 19 0 77 NA NA NA NA NA NA 37226 XM_029323975.2 1065 1241 724 562 406 Q27433 1.66e-119 Mechanosensory protein 2 Caenorhabditis elegans detection of mechanical stimulus involved in sensory perception of touch [GO:0050976]; mechanosensory behavior [GO:0007638]; positive regulation of detection of mechanical stimulus involved in sensory perception of touch [GO:1905789]; positive regulation of mechanosensory behavior [GO:1905792]; potassium ion transport [GO:0006813]; response to mechanical stimulus [GO:0009612] GO:0005272; GO:0005886; GO:0006813; GO:0007638; GO:0009612; GO:0015485; GO:0032589; GO:0043005; GO:0050976; GO:1905789; GO:1905792 37227 XM_044312348.1 20 3 6 13 28 NA NA NA NA NA NA 37228 XM_029341449.2 775 108 388 850 797 Q6NUT3 2.66e-79 Major facilitator superfamily domain-containing protein 12 Homo sapiens (Human) carbohydrate transport [GO:0008643]; cysteine transmembrane transport [GO:1903712]; melanin biosynthetic process [GO:0042438]; negative regulation of melanin biosynthetic process [GO:0048022]; organic substance transport [GO:0071702]; pigment metabolic process involved in pigmentation [GO:0043474]; regulation of melanin biosynthetic process [GO:0048021] GO:0005764; GO:0005765; GO:0005770; GO:0005886; GO:0008643; GO:0015293; GO:0033162; GO:0033229; GO:0042438; GO:0042470; GO:0043474; GO:0048021; GO:0048022; GO:0071702; GO:1903712 37229 XM_029330691.2 465 345 265 256 298 Q9D0S4 1.15e-32 Neuralized-like protein 2 Mus musculus (Mouse) intracellular signal transduction [GO:0035556]; myofibril assembly [GO:0030239]; sarcomere organization [GO:0045214] GO:0005927; GO:0030239; GO:0030891; GO:0035556; GO:0045214; GO:0061630 37230 XM_044312897.1 11 42 23 14 23 P55006 4.51e-75 Retinol dehydrogenase 7 (EC 1.1.1.105) (Retinol dehydrogenase 3) (Retinol dehydrogenase type III) (RODH III) Rattus norvegicus (Rat) retinol metabolic process [GO:0042572]; steroid metabolic process [GO:0008202] GO:0004745; GO:0005783; GO:0008202; GO:0016491; GO:0042572; GO:0043231 37231 XM_044317428.1 7 366 88 117 136 NA NA NA NA NA NA 37232 XM_029334151.2 109 96 221 401 256 NA NA NA NA NA NA 37233 XM_029337518.2 68 154 360 341 13 Q4TZY1 1.42e-103 ATP-sensitive inward rectifier potassium channel 12 (Potassium channel, inwardly rectifying subfamily J member 12) Bos taurus (Bovine) potassium ion import across plasma membrane [GO:1990573]; potassium ion transport [GO:0006813]; protein homotetramerization [GO:0051289]; regulation of ion transmembrane transport [GO:0034765] GO:0005242; GO:0005886; GO:0006813; GO:0016020; GO:0034765; GO:0051289; GO:1990573 37234 XM_029346313.2 287 119 189 300 393 Q766D5 1.41e-58 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Mus musculus (Mouse) chondroitin sulfate biosynthetic process [GO:0030206] GO:0008376; GO:0030206; GO:0032580; GO:0033842; GO:0047238 37235 XM_044323988.1 36 488 152 373 360 NA NA NA NA NA NA 37236 XM_029335800.2 120 94 53 69 100 Q8K3P0 8.98e-72 Short-chain dehydrogenase/reductase family 9C member 7 (EC 1.1.1.-) (Orphan short-chain dehydrogenase/reductase) (SDR-O) (RDH-S) Mus musculus (Mouse) retinol metabolic process [GO:0042572]; steroid metabolic process [GO:0008202] GO:0004745; GO:0005737; GO:0008202; GO:0016491; GO:0042572; GO:0043231 37237 XM_044310957.1 5 16 0 0 2 NA NA NA NA NA NA 37238 XM_029328523.2 1113 1363 698 1374 1260 Q6GNG3 5.67e-85 Protein disulfide-isomerase TMX3 (EC 5.3.4.1) (Thioredoxin domain-containing protein 10) (Thioredoxin-related transmembrane protein 3) Xenopus laevis (African clawed frog) NA GO:0003756; GO:0005789 37239 XM_029341021.2 25 17 20 1 40 NA NA NA NA NA NA 37240 XM_029340145.2 0 72 0 65 209 O46504 9.56e-170 Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial (PDPr) Bos taurus (Bovine) NA GO:0005759; GO:0016491 37241 XM_044322763.1 94 260 38 47 183 P55011 0 Solute carrier family 12 member 2 (Basolateral Na-K-Cl symporter) (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2) Homo sapiens (Human) aging [GO:0007568]; ammonium transmembrane transport [GO:0072488]; cell volume homeostasis [GO:0006884]; cellular chloride ion homeostasis [GO:0030644]; cellular potassium ion homeostasis [GO:0030007]; cellular response to chemokine [GO:1990869]; cellular response to potassium ion [GO:0035865]; cellular sodium ion homeostasis [GO:0006883]; chloride ion homeostasis [GO:0055064]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid signaling pathway [GO:0007214]; hyperosmotic response [GO:0006972]; inorganic anion import across plasma membrane [GO:0098658]; inorganic cation import across plasma membrane [GO:0098659]; ion transport [GO:0006811]; maintenance of blood-brain barrier [GO:0035633]; negative regulation of vascular wound healing [GO:0061044]; positive regulation of aspartate secretion [GO:1904450]; positive regulation of cell volume [GO:0045795]; potassium ion homeostasis [GO:0055075]; potassium ion import across plasma membrane [GO:1990573]; regulation of matrix metallopeptidase secretion [GO:1904464]; regulation of spontaneous synaptic transmission [GO:0150003]; sodium ion homeostasis [GO:0055078]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725]; T cell chemotaxis [GO:0010818]; transepithelial ammonium transport [GO:0070634]; transepithelial chloride transport [GO:0030321]; transport across blood-brain barrier [GO:0150104] GO:0005829; GO:0005886; GO:0006811; GO:0006883; GO:0006884; GO:0006972; GO:0007214; GO:0007568; GO:0008511; GO:0008519; GO:0009925; GO:0010818; GO:0015079; GO:0015377; GO:0015379; GO:0016020; GO:0016323; GO:0016324; GO:0016328; GO:0019901; GO:0030007; GO:0030321; GO:0030644; GO:0030659; GO:0031253; GO:0035633; GO:0035725; GO:0035865; GO:0042995; GO:0043005; GO:0043025; GO:0044297; GO:0044298; GO:0045795; GO:0046873; GO:0051087; GO:0051879; GO:0055064; GO:0055075; GO:0055078; GO:0061044; GO:0070062; GO:0070634; GO:0071944; GO:0072488; GO:0098658; GO:0098659; GO:0098719; GO:0150003; GO:0150104; GO:1902476; GO:1903561; GO:1904450; GO:1904464; GO:1990573; GO:1990869 37242 XM_029339783.2 533 482 286 497 326 P59083 2.18e-38 14 kDa phosphohistidine phosphatase (EC 3.9.1.3) (Phosphohistidine phosphatase 1) (PHPT1) (Protein histidine phosphatase) (PHP) Sus scrofa (Pig) peptidyl-histidine dephosphorylation [GO:0035971] GO:0005829; GO:0035971; GO:0101006 37243 XM_044318383.1 4 0 8 1 56 NA NA NA NA NA NA 37244 XR_006395269.1 0 0 0 2 6 NA NA NA NA NA NA 37245 XM_044326459.1 387 141 85 147 54 Q6DBU5 0 Mannose-1-phosphate guanyltransferase beta (EC 2.7.7.13) (GDP-mannose pyrophosphorylase B) (GTP-mannose-1-phosphate guanylyltransferase beta) Danio rerio (Zebrafish) (Brachydanio rerio) GDP-mannose biosynthetic process [GO:0009298]; protein glycosylation [GO:0006486] GO:0004475; GO:0005525; GO:0005737; GO:0006486; GO:0009298; GO:0016779 37246 XM_044327109.1 141 52 35 77 115 NA NA NA NA NA NA 37247 XM_044311328.1 9 0 16 0 33 NA NA NA NA NA NA 37248 XM_029354429.2 10 0 2 4 18 A3RL54 0 NA NA NA NA 37249 XM_029358065.2 11309 15619 6704 6299 6778 P23935 5.23e-34 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (Complex I subunit B13) (Complex I-13kD-B) (CI-13kD-B) (NADH-ubiquinone oxidoreductase 13 kDa-B subunit) Bos taurus (Bovine) mitochondrial respiratory chain complex I assembly [GO:0032981]; respiratory electron transport chain [GO:0022904] GO:0005747; GO:0022904; GO:0032981 37250 XR_003824534.2 25 4 2 2 10 NA NA NA NA NA NA 37251 XM_044326744.1 132 40 117 79 69 NA NA NA NA NA NA 37252 XM_029335043.2 68 82 0 13 0 Q6GQN5 9.31e-68 Protein phosphatase 1 regulatory subunit 42 (Leucine-rich repeat-containing protein 67) Danio rerio (Zebrafish) (Brachydanio rerio) positive regulation of protein dephosphorylation [GO:0035307] GO:0000164; GO:0002177; GO:0003779; GO:0004865; GO:0005813; GO:0005815; GO:0015630; GO:0015631; GO:0035307; GO:0070840 37253 XM_029357990.2 70 55 56 71 120 Q6ZQY2 1.19e-23 Leucine-rich repeat-containing protein 74B Homo sapiens (Human) NA NA 37254 XM_044314731.1 433 245 150 243 413 Q7RTR2 1.72e-68 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 37255 XM_044314731.1 433 245 150 243 413 Q7RTR2 2.33e-68 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 37256 XM_044314731.1 433 245 150 243 413 Q7RTR2 2.84e-56 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 37257 XM_044314731.1 433 245 150 243 413 Q7RTR2 2.79e-43 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 37258 XM_044321917.1 0 95 0 98 125 Q9ESJ0 0 Exportin-4 (Exp4) Mus musculus (Mouse) positive regulation of protein export from nucleus [GO:0046827]; protein export from nucleus [GO:0006611] GO:0005049; GO:0005643; GO:0005654; GO:0005737; GO:0005829; GO:0006611; GO:0046827 37259 XR_006395519.1 190 350 1 124 53 NA NA NA NA NA NA 37260 XR_006393588.1 500 25 20 446 118 NA NA NA NA NA NA 37261 XM_044309865.1 0 5 0 0 9 NA NA NA NA NA NA 37262 XM_029358246.2 7 40 25 6 13 NA NA NA NA NA NA 37263 XR_003827896.2 0 0 118 26 37 NA NA NA NA NA NA 37264 XM_044321145.1 81 114 23 0 0 Q9NYT0 1.05e-45 Pleckstrin-2 Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; intracellular signal transduction [GO:0035556]; positive regulation of plasma membrane bounded cell projection assembly [GO:0120034] GO:0005737; GO:0005856; GO:0005886; GO:0031258; GO:0031532; GO:0032266; GO:0035556; GO:0043325; GO:0080025; GO:0120034 37265 XM_044316685.1 1094 738 715 794 752 P27170 9.99e-43 Serum paraoxonase/arylesterase 1 (PON 1) (EC 3.1.1.2) (EC 3.1.1.81) (EC 3.1.8.1) (Aromatic esterase 1) (A-esterase 1) (Serum aryldialkylphosphatase 1) Oryctolagus cuniculus (Rabbit) response to organophosphorus [GO:0046683] GO:0004063; GO:0004064; GO:0005509; GO:0016209; GO:0034364; GO:0046683; GO:0102007 37266 XM_029355627.2 809 58 216 51 0 Q5R8G6 0 DNA replication licensing factor MCM3 (EC 3.6.4.12) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cell cycle [GO:0007049]; DNA replication initiation [GO:0006270]; DNA unwinding involved in DNA replication [GO:0006268]; regulation of DNA-templated DNA replication initiation [GO:0030174] GO:0003677; GO:0004386; GO:0005524; GO:0006268; GO:0006270; GO:0007049; GO:0016887; GO:0030174; GO:0042555; GO:0071162 37267 XM_029341867.2 793 488 325 882 416 Q9QZU7 1.76e-79 Gamma-butyrobetaine dioxygenase (EC 1.14.11.1) (Gamma-butyrobetaine hydroxylase) (Gamma-BBH) (Gamma-butyrobetaine,2-oxoglutarate dioxygenase) Rattus norvegicus (Rat) carnitine biosynthetic process [GO:0045329] GO:0005506; GO:0005739; GO:0008270; GO:0008336; GO:0042802; GO:0045329 37268 XM_044308349.1 7 0 0 0 13 B4E2M5 4.63e-23 Ankyrin repeat domain-containing protein 66 Homo sapiens (Human) NA NA 37269 XM_029337625.2 115 91 58 16 110 Q5R7X9 1.09e-104 Cell cycle checkpoint protein RAD1 (EC 3.1.11.2) (DNA repair exonuclease rad1 homolog) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cellular response to ionizing radiation [GO:0071479]; DNA damage checkpoint signaling [GO:0000077]; DNA repair [GO:0006281]; meiotic recombination checkpoint signaling [GO:0051598] GO:0000077; GO:0005654; GO:0005694; GO:0006281; GO:0008408; GO:0008853; GO:0051598; GO:0071479 37270 XM_029334843.2 166 72 79 135 305 O60678 8.33e-155 Protein arginine N-methyltransferase 3 (EC 2.1.1.319) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3) Homo sapiens (Human) dendritic spine morphogenesis [GO:0060997]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of retinoic acid biosynthetic process [GO:1900053]; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [GO:0019919]; protein methylation [GO:0006479] GO:0005737; GO:0005829; GO:0006479; GO:0008168; GO:0016274; GO:0019919; GO:0031397; GO:0035241; GO:0035242; GO:0043022; GO:0046872; GO:0060997; GO:0072341; GO:1900053 37271 XM_029323831.2 30 9 9 12 35 NA NA NA NA NA NA 37272 XM_029329347.2 456 276 235 274 427 Q8N137 5.96e-60 Centrobin (Centrosomal BRCA2-interacting protein) (LYST-interacting protein 8) Homo sapiens (Human) centriole replication [GO:0007099]; centrosome separation [GO:0051299]; mitotic cytokinetic process [GO:1902410]; regulation of cilium assembly [GO:1902017] GO:0005737; GO:0005813; GO:0005814; GO:0007099; GO:0019904; GO:0051299; GO:1902017; GO:1902410 37273 XM_044324768.1 95 40 31 71 21 P35546 1.13e-83 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; anatomical structure morphogenesis [GO:0009653]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006919; GO:0007156; GO:0007158; GO:0007169; GO:0007399; GO:0009410; GO:0009653; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030182; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0098797; GO:2001241 37274 XR_003827726.2 41 6 3 18 80 NA NA NA NA NA NA 37275 XM_044328587.1 5 7 25 2 61 E9Q236 0 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 37276 XM_029338435.2 309 35 0 0 350 A4QNN3 5.44e-75 Ubiquitin carboxyl-terminal hydrolase 30 (EC 3.4.19.12) (Deubiquitinating enzyme 30) (Ubiquitin thioesterase 30) (Ubiquitin-specific-processing protease 30) (Ub-specific protease 30) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) autophagy of mitochondrion [GO:0000422]; mitochondrial fusion [GO:0008053]; protein deubiquitination [GO:0016579]; protein K11-linked deubiquitination [GO:0035871]; protein K6-linked deubiquitination [GO:0044313]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000422; GO:0004197; GO:0004843; GO:0005739; GO:0005741; GO:0006511; GO:0008053; GO:0016579; GO:0035871; GO:0044313 37277 XM_044308631.1 19 0 0 4 4 P0CT40 1.44e-85 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 37278 XM_044311882.1 64 170 37 12 77 NA NA NA NA NA NA 37279 XM_044314893.1 11 12 13 9 13 NA NA NA NA NA NA 37280 XM_044315702.1 259 112 85 144 189 Q12955 5e-73 Ankyrin-3 (ANK-3) (Ankyrin-G) Homo sapiens (Human) axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165] GO:0000281; GO:0005200; GO:0005764; GO:0005783; GO:0005794; GO:0005829; GO:0005886; GO:0007009; GO:0007165; GO:0007409; GO:0007528; GO:0008092; GO:0008093; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014704; GO:0014731; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030425; GO:0030507; GO:0030674; GO:0031594; GO:0033268; GO:0034112; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045184; GO:0045211; GO:0045296; GO:0045838; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:1900827; GO:1902260; GO:2000651; GO:2001259 37281 XM_044315702.1 259 112 85 144 189 Q12955 1.76e-61 Ankyrin-3 (ANK-3) (Ankyrin-G) Homo sapiens (Human) axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165] GO:0000281; GO:0005200; GO:0005764; GO:0005783; GO:0005794; GO:0005829; GO:0005886; GO:0007009; GO:0007165; GO:0007409; GO:0007528; GO:0008092; GO:0008093; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014704; GO:0014731; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030425; GO:0030507; GO:0030674; GO:0031594; GO:0033268; GO:0034112; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045184; GO:0045211; GO:0045296; GO:0045838; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:1900827; GO:1902260; GO:2000651; GO:2001259 37282 XM_044315702.1 259 112 85 144 189 Q12955 2.44e-52 Ankyrin-3 (ANK-3) (Ankyrin-G) Homo sapiens (Human) axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165] GO:0000281; GO:0005200; GO:0005764; GO:0005783; GO:0005794; GO:0005829; GO:0005886; GO:0007009; GO:0007165; GO:0007409; GO:0007528; GO:0008092; GO:0008093; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014704; GO:0014731; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030425; GO:0030507; GO:0030674; GO:0031594; GO:0033268; GO:0034112; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045184; GO:0045211; GO:0045296; GO:0045838; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:1900827; GO:1902260; GO:2000651; GO:2001259 37283 XM_044315702.1 259 112 85 144 189 Q12955 3.14e-49 Ankyrin-3 (ANK-3) (Ankyrin-G) Homo sapiens (Human) axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165] GO:0000281; GO:0005200; GO:0005764; GO:0005783; GO:0005794; GO:0005829; GO:0005886; GO:0007009; GO:0007165; GO:0007409; GO:0007528; GO:0008092; GO:0008093; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014704; GO:0014731; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030425; GO:0030507; GO:0030674; GO:0031594; GO:0033268; GO:0034112; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045184; GO:0045211; GO:0045296; GO:0045838; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:1900827; GO:1902260; GO:2000651; GO:2001259 37284 XM_044315702.1 259 112 85 144 189 Q12955 1.9e-41 Ankyrin-3 (ANK-3) (Ankyrin-G) Homo sapiens (Human) axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165] GO:0000281; GO:0005200; GO:0005764; GO:0005783; GO:0005794; GO:0005829; GO:0005886; GO:0007009; GO:0007165; GO:0007409; GO:0007528; GO:0008092; GO:0008093; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014704; GO:0014731; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030425; GO:0030507; GO:0030674; GO:0031594; GO:0033268; GO:0034112; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045184; GO:0045211; GO:0045296; GO:0045838; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:1900827; GO:1902260; GO:2000651; GO:2001259 37285 XM_044317373.1 160 87 138 87 89 Q7Z020 1.56e-134 Transient receptor potential cation channel subfamily A member 1 (dTRPA1) (Ankyrin-like with transmembrane domains protein 1) (dANKTM1) Drosophila melanogaster (Fruit fly) calcium ion transport [GO:0006816]; cation transport [GO:0006812]; cellular response to heat [GO:0034605]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; detection of temperature stimulus involved in thermoception [GO:0050960]; mechanosensory behavior [GO:0007638]; negative phototaxis [GO:0046957]; neuronal signal transduction [GO:0023041]; phototransduction [GO:0007602]; positive regulation of calcium-mediated signaling [GO:0050850]; response to heat [GO:0009408]; response to light stimulus [GO:0009416]; temperature compensation of the circadian clock [GO:0010378]; thermosensory behavior [GO:0040040]; thermotaxis [GO:0043052] GO:0001580; GO:0005261; GO:0005262; GO:0005886; GO:0006812; GO:0006816; GO:0007602; GO:0007638; GO:0009408; GO:0009416; GO:0010378; GO:0015276; GO:0016020; GO:0023041; GO:0034605; GO:0034703; GO:0040040; GO:0043052; GO:0046957; GO:0050850; GO:0050960; GO:0050965; GO:0050968; GO:0097604 37286 XM_044309193.1 345 228 255 472 337 Q9WV76 3.56e-160 AP-4 complex subunit beta-1 (AP-4 adaptor complex subunit beta) (Adaptor-related protein complex 4 subunit beta-1) (Beta subunit of AP-4) (Beta4-adaptin) Mus musculus (Mouse) intracellular protein transport [GO:0006886]; protein localization to somatodendritic compartment [GO:0061938]; protein targeting [GO:0006605]; vesicle-mediated transport [GO:0016192] GO:0005802; GO:0005829; GO:0006605; GO:0006886; GO:0016192; GO:0030124; GO:0030131; GO:0030276; GO:0061938; GO:0098541 37287 XM_029350230.2 806 1081 510 888 1090 B2RQL2 1.46e-24 Storkhead-box protein 1 Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to nitrosative stress [GO:0071500]; inner ear development [GO:0048839]; negative regulation of gene expression [GO:0010629]; positive regulation of cell cycle [GO:0045787]; positive regulation of cyclin-dependent protein kinase activity [GO:1904031]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of gene expression [GO:0010628]; positive regulation of otic vesicle morphogenesis [GO:1904120]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression [GO:0010468]; regulation of mitochondrial DNA metabolic process [GO:1901858]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mitochondrion organization [GO:0010821]; regulation of mitotic cell cycle [GO:0007346]; regulation of response to oxidative stress [GO:1902882]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418] GO:0000977; GO:0001228; GO:0001650; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007049; GO:0007346; GO:0010468; GO:0010628; GO:0010629; GO:0010800; GO:0010821; GO:0010971; GO:0033138; GO:0045787; GO:0045944; GO:0048839; GO:0051301; GO:0051881; GO:0051897; GO:0061418; GO:0071500; GO:1900087; GO:1901858; GO:1902882; GO:1904031; GO:1904120 37288 XM_029327081.2 1153 762 556 987 898 Q9CYC6 1.41e-85 m7GpppN-mRNA hydrolase (EC 3.6.1.62) (mRNA-decapping enzyme 2) Mus musculus (Mouse) deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; histone mRNA catabolic process [GO:0071044]; mRNA catabolic process [GO:0006402]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of mRNA stability [GO:0043488]; regulation of telomerase RNA localization to Cajal body [GO:1904872] GO:0000184; GO:0000290; GO:0000932; GO:0003723; GO:0004534; GO:0005654; GO:0005737; GO:0006402; GO:0016442; GO:0030054; GO:0030145; GO:0032211; GO:0036464; GO:0043488; GO:0050072; GO:0071044; GO:0140933; GO:1904872 37289 XM_029331828.2 1864 1275 848 1501 1640 Q2KIR1 1.19e-44 U1 small nuclear ribonucleoprotein A (U1 snRNP A) (U1-A) (U1A) Bos taurus (Bovine) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0003723; GO:0005654; GO:0005681; GO:0005685; GO:0030619; GO:0042802; GO:0046540 37290 XM_029331828.2 1864 1275 848 1501 1640 Q2KIR1 1.17e-32 U1 small nuclear ribonucleoprotein A (U1 snRNP A) (U1-A) (U1A) Bos taurus (Bovine) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0003723; GO:0005654; GO:0005681; GO:0005685; GO:0030619; GO:0042802; GO:0046540 37291 XM_044314930.1 0 0 73 0 0 NA NA NA NA NA NA 37292 XM_029345951.2 0 0 88 0 206 Q91175 5.95e-38 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (MAR1) Oryzias latipes (Japanese rice fish) (Japanese killifish) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of vasoconstriction [GO:0045907] GO:0001996; GO:0004930; GO:0004937; GO:0005886; GO:0007200; GO:0007204; GO:0007267; GO:0043410; GO:0045907; GO:0071880 37293 XM_029333874.2 694 495 422 904 590 Q4G0X9 0 Coiled-coil domain-containing protein 40 Homo sapiens (Human) axonemal dynein complex assembly [GO:0070286]; axoneme assembly [GO:0035082]; cilium movement [GO:0003341]; determination of digestive tract left/right asymmetry [GO:0071907]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; flagellated sperm motility [GO:0030317]; heart looping [GO:0001947]; inner dynein arm assembly [GO:0036159]; lung development [GO:0030324]; motile cilium assembly [GO:0044458]; regulation of cilium beat frequency [GO:0003356] GO:0001947; GO:0003341; GO:0003351; GO:0003356; GO:0005576; GO:0005737; GO:0005929; GO:0005930; GO:0030317; GO:0030324; GO:0035082; GO:0035469; GO:0036159; GO:0044458; GO:0060287; GO:0070286; GO:0071907; GO:0071910 37294 XR_006397200.1 23 2 32 14 71 NA NA NA NA NA NA 37295 XM_029338378.2 0 24 31 0 140 NA NA NA NA NA NA 37296 XM_044322330.1 15 5 3 2 18 Q09575 1.97e-36 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 37297 XM_029338782.2 287 8810 3038 184 1629 NA NA NA NA NA NA 37298 XR_003825318.2 2 0 0 1 22 NA NA NA NA NA NA 37299 XM_029357845.2 15 122 2 6 3 NA NA NA NA NA NA 37300 XM_044323777.1 7 18 36 31 16 NA NA NA NA NA NA 37301 XM_044309919.1 9 0 3 0 8 NA NA NA NA NA NA 37302 XM_044317773.1 932 415 430 713 603 NA NA NA NA NA NA 37303 XR_006394958.1 1147 1095 683 1623 2150 NA NA NA NA NA NA 37304 XM_029356450.2 125 126 110 282 225 E2JA28 1.88e-38 Dapdiamide synthesis protein DdaC (EC 1.-.-.-) Enterobacter agglomerans (Erwinia herbicola) (Pantoea agglomerans) antibiotic biosynthetic process [GO:0017000] GO:0016491; GO:0017000 37305 XR_003824418.2 0 0 14 6 13 NA NA NA NA NA NA 37306 XM_044313910.1 27 2 8 30 28 NA NA NA NA NA NA 37307 XM_029339921.2 2444 2171 1601 3789 3922 P31422 0 Metabotropic glutamate receptor 3 (mGluR3) Rattus norvegicus (Rat) G protein-coupled glutamate receptor signaling pathway [GO:0007216]; gene expression [GO:0010467]; modulation of chemical synaptic transmission [GO:0050804]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; regulation of synaptic transmission, glutamatergic [GO:0051966]; sensory perception of pain [GO:0019233] GO:0001640; GO:0001641; GO:0005246; GO:0005886; GO:0007216; GO:0010467; GO:0014069; GO:0019233; GO:0030424; GO:0042734; GO:0043005; GO:0043197; GO:0045211; GO:0050804; GO:0051966; GO:0097110; GO:0097449; GO:0098794; GO:0098978; GO:0099170 37308 XM_044308757.1 95 43 31 100 55 Q5XXP2 5.34e-30 Melanopsin (Opsin-4) Phodopus sungorus (Striped hairy-footed hamster) (Djungarian hamster) hyaloid vascular plexus regression [GO:1990384]; optokinetic behavior [GO:0007634]; phototransduction [GO:0007602]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511]; visual perception [GO:0007601] GO:0005502; GO:0005886; GO:0007601; GO:0007602; GO:0007634; GO:0008020; GO:0016020; GO:0030424; GO:0030425; GO:0042752; GO:0043204; GO:0048511; GO:1990384 37309 XR_006391668.1 67 72 67 91 146 NA NA NA NA NA NA 37310 XM_029345604.2 453 111 483 400 164 Q8TEL6 1.22e-147 Short transient receptor potential channel 4-associated protein (Trp4-associated protein) (Trpc4-associated protein) (Protein TAP1) (TNF-receptor ubiquitous scaffolding/signaling protein) (Protein TRUSS) Homo sapiens (Human) calcium ion transmembrane transport [GO:0070588]; hair follicle maturation [GO:0048820]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent protein catabolic process via the C-end degron rule pathway [GO:0140627] GO:0005262; GO:0005886; GO:0006511; GO:0016567; GO:0019902; GO:0031464; GO:0048471; GO:0048820; GO:0070588; GO:0080008; GO:0140627; GO:1990756 37311 XM_029339139.2 5250 2906 1887 3504 2591 NA NA NA NA NA NA 37312 XM_044307429.1 0 252 0 454 553 Q9NR09 3.36e-176 Baculoviral IAP repeat-containing protein 6 (EC 2.3.2.27) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (RING-type E3 ubiquitin transferase BIRC6) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON) Homo sapiens (Human) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell population proliferation [GO:0008283]; labyrinthine layer development [GO:0060711]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of peptidase activity [GO:0010466]; positive regulation of cell population proliferation [GO:0008284]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell population proliferation [GO:0042127]; regulation of cytokinesis [GO:0032465]; regulation of endopeptidase activity [GO:0052548]; spongiotrophoblast layer development [GO:0060712] GO:0000922; GO:0004842; GO:0004869; GO:0005634; GO:0005768; GO:0005802; GO:0005815; GO:0005829; GO:0006468; GO:0006915; GO:0007049; GO:0008283; GO:0008284; GO:0010466; GO:0016020; GO:0016567; GO:0030496; GO:0032465; GO:0042127; GO:0043066; GO:0051301; GO:0052548; GO:0060711; GO:0060712; GO:0061631; GO:0090543; GO:2001237 37313 XM_044307429.1 0 252 0 454 553 Q9NR09 3.91e-91 Baculoviral IAP repeat-containing protein 6 (EC 2.3.2.27) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (RING-type E3 ubiquitin transferase BIRC6) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON) Homo sapiens (Human) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell population proliferation [GO:0008283]; labyrinthine layer development [GO:0060711]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of peptidase activity [GO:0010466]; positive regulation of cell population proliferation [GO:0008284]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell population proliferation [GO:0042127]; regulation of cytokinesis [GO:0032465]; regulation of endopeptidase activity [GO:0052548]; spongiotrophoblast layer development [GO:0060712] GO:0000922; GO:0004842; GO:0004869; GO:0005634; GO:0005768; GO:0005802; GO:0005815; GO:0005829; GO:0006468; GO:0006915; GO:0007049; GO:0008283; GO:0008284; GO:0010466; GO:0016020; GO:0016567; GO:0030496; GO:0032465; GO:0042127; GO:0043066; GO:0051301; GO:0052548; GO:0060711; GO:0060712; GO:0061631; GO:0090543; GO:2001237 37314 XM_044307429.1 0 252 0 454 553 Q9NR09 5.54e-73 Baculoviral IAP repeat-containing protein 6 (EC 2.3.2.27) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (RING-type E3 ubiquitin transferase BIRC6) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON) Homo sapiens (Human) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell population proliferation [GO:0008283]; labyrinthine layer development [GO:0060711]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of peptidase activity [GO:0010466]; positive regulation of cell population proliferation [GO:0008284]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell population proliferation [GO:0042127]; regulation of cytokinesis [GO:0032465]; regulation of endopeptidase activity [GO:0052548]; spongiotrophoblast layer development [GO:0060712] GO:0000922; GO:0004842; GO:0004869; GO:0005634; GO:0005768; GO:0005802; GO:0005815; GO:0005829; GO:0006468; GO:0006915; GO:0007049; GO:0008283; GO:0008284; GO:0010466; GO:0016020; GO:0016567; GO:0030496; GO:0032465; GO:0042127; GO:0043066; GO:0051301; GO:0052548; GO:0060711; GO:0060712; GO:0061631; GO:0090543; GO:2001237 37315 XM_044307429.1 0 252 0 454 553 Q9NR09 1.16e-56 Baculoviral IAP repeat-containing protein 6 (EC 2.3.2.27) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (RING-type E3 ubiquitin transferase BIRC6) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON) Homo sapiens (Human) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell population proliferation [GO:0008283]; labyrinthine layer development [GO:0060711]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of peptidase activity [GO:0010466]; positive regulation of cell population proliferation [GO:0008284]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell population proliferation [GO:0042127]; regulation of cytokinesis [GO:0032465]; regulation of endopeptidase activity [GO:0052548]; spongiotrophoblast layer development [GO:0060712] GO:0000922; GO:0004842; GO:0004869; GO:0005634; GO:0005768; GO:0005802; GO:0005815; GO:0005829; GO:0006468; GO:0006915; GO:0007049; GO:0008283; GO:0008284; GO:0010466; GO:0016020; GO:0016567; GO:0030496; GO:0032465; GO:0042127; GO:0043066; GO:0051301; GO:0052548; GO:0060711; GO:0060712; GO:0061631; GO:0090543; GO:2001237 37316 XM_044307429.1 0 252 0 454 553 Q9NR09 2.28e-33 Baculoviral IAP repeat-containing protein 6 (EC 2.3.2.27) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (RING-type E3 ubiquitin transferase BIRC6) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON) Homo sapiens (Human) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell population proliferation [GO:0008283]; labyrinthine layer development [GO:0060711]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of peptidase activity [GO:0010466]; positive regulation of cell population proliferation [GO:0008284]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell population proliferation [GO:0042127]; regulation of cytokinesis [GO:0032465]; regulation of endopeptidase activity [GO:0052548]; spongiotrophoblast layer development [GO:0060712] GO:0000922; GO:0004842; GO:0004869; GO:0005634; GO:0005768; GO:0005802; GO:0005815; GO:0005829; GO:0006468; GO:0006915; GO:0007049; GO:0008283; GO:0008284; GO:0010466; GO:0016020; GO:0016567; GO:0030496; GO:0032465; GO:0042127; GO:0043066; GO:0051301; GO:0052548; GO:0060711; GO:0060712; GO:0061631; GO:0090543; GO:2001237 37317 XM_044307429.1 0 252 0 454 553 Q9NR09 6.02e-32 Baculoviral IAP repeat-containing protein 6 (EC 2.3.2.27) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (RING-type E3 ubiquitin transferase BIRC6) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON) Homo sapiens (Human) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell population proliferation [GO:0008283]; labyrinthine layer development [GO:0060711]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of peptidase activity [GO:0010466]; positive regulation of cell population proliferation [GO:0008284]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell population proliferation [GO:0042127]; regulation of cytokinesis [GO:0032465]; regulation of endopeptidase activity [GO:0052548]; spongiotrophoblast layer development [GO:0060712] GO:0000922; GO:0004842; GO:0004869; GO:0005634; GO:0005768; GO:0005802; GO:0005815; GO:0005829; GO:0006468; GO:0006915; GO:0007049; GO:0008283; GO:0008284; GO:0010466; GO:0016020; GO:0016567; GO:0030496; GO:0032465; GO:0042127; GO:0043066; GO:0051301; GO:0052548; GO:0060711; GO:0060712; GO:0061631; GO:0090543; GO:2001237 37318 XM_029347924.2 1140 823 556 911 719 Q26613 4.59e-171 77 kDa echinoderm microtubule-associated protein Strongylocentrotus purpuratus (Purple sea urchin) microtubule cytoskeleton organization [GO:0000226] GO:0000226; GO:0005737; GO:0005874; GO:0008017 37319 XM_044310769.1 34 1 8 16 123 NA NA NA NA NA NA 37320 XM_029325297.2 2186 1477 2639 2347 1331 Q54271 7.77e-48 Phosphonopyruvate decarboxylase (EC 4.1.1.82) Streptomyces hygroscopicus antibiotic biosynthetic process [GO:0017000]; organic phosphonate biosynthetic process [GO:0032923] GO:0000287; GO:0017000; GO:0030976; GO:0032923; GO:0033980 37321 XM_029328924.2 508 1159 649 226 229 P07463 7.85e-37 Calmodulin (CaM) Paramecium tetraurelia NA GO:0005509; GO:0030234 37322 XM_029344452.2 532 195 245 541 401 Q90419 9.25e-95 Tiggy-winkle hedgehog protein (TWHH) (EC 3.1.-.-) (Sonic hedgehog protein B) (SHHB) [Cleaved into: Tiggy-winkle hedgehog protein N-product (Shh N-terminal processed signaling domains) (ShhNp) (Sonic hedgehog protein N-product) (ShhN)] Danio rerio (Zebrafish) (Brachydanio rerio) cell fate specification [GO:0001708]; cell-cell signaling [GO:0007267]; embryonic neurocranium morphogenesis [GO:0048702]; embryonic viscerocranium morphogenesis [GO:0048703]; endocardial cell differentiation [GO:0060956]; forebrain development [GO:0030900]; gliogenesis [GO:0042063]; neuron differentiation [GO:0030182]; neuron fate commitment [GO:0048663]; oligodendrocyte differentiation [GO:0048709]; positive regulation of smoothened signaling pathway [GO:0045880]; protein autoprocessing [GO:0016540]; regulation of gene expression [GO:0010468]; self proteolysis [GO:0097264]; smoothened signaling pathway [GO:0007224]; striated muscle cell development [GO:0055002] GO:0000139; GO:0001708; GO:0005113; GO:0005509; GO:0005615; GO:0005789; GO:0005886; GO:0007224; GO:0007267; GO:0008233; GO:0010468; GO:0016540; GO:0030182; GO:0030900; GO:0042063; GO:0045880; GO:0048663; GO:0048702; GO:0048703; GO:0048709; GO:0055002; GO:0060956; GO:0097264; GO:0140853 37323 XM_044326779.1 38 0 0 4 198 NA NA NA NA NA NA 37324 XM_044310790.1 80 20 585 13 394 NA NA NA NA NA NA 37325 XM_044317239.1 26 4 7 6 242 NA NA NA NA NA NA 37326 XM_044309471.1 2 6 5 6 6 NA NA NA NA NA NA 37327 XM_029323563.2 1310 307 266 715 606 Q69ZS0 1.67e-59 E3 ubiquitin-protein ligase PDZRN3 (EC 2.3.2.27) (PDZ domain-containing RING finger protein 3) (RING-type E3 ubiquitin transferase PDZRN3) (Semaphorin cytoplasmic domain-associated protein 3) (Protein SEMACAP3) Mus musculus (Mouse) neuromuscular junction development [GO:0007528]; protein ubiquitination [GO:0016567] GO:0004842; GO:0005737; GO:0007528; GO:0008270; GO:0016567; GO:0031594; GO:0061630 37328 XM_029349434.2 295 251 214 454 184 Q6ZQ88 0 Lysine-specific histone demethylase 1A (EC 1.14.99.66) (BRAF35-HDAC complex protein BHC110) (Flavin-containing amine oxidase domain-containing protein 2) Mus musculus (Mouse) cell differentiation [GO:0030154]; cellular response to gamma radiation [GO:0071480]; cellular response to UV [GO:0034644]; DNA repair-dependent chromatin remodeling [GO:0140861]; granulocyte differentiation [GO:0030851]; guanine metabolic process [GO:0046098]; histone H3-K4 demethylation [GO:0034720]; histone H3-K9 demethylation [GO:0033169]; histone modification [GO:0016570]; muscle cell development [GO:0055001]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone H3-K9 methylation [GO:0051573]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of neurogenesis [GO:0050768]; negative regulation of protein binding [GO:0032091]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron projection extension [GO:1990138]; pituitary gland development [GO:0021983]; positive regulation of cell size [GO:0045793]; positive regulation of chromatin binding [GO:0035563]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein demethylation [GO:0006482]; regulation of DNA methylation-dependent heterochromatin formation [GO:0090308]; regulation of double-strand break repair via homologous recombination [GO:0010569]; regulation of neurogenesis [GO:0050767]; regulation of primitive erythrocyte differentiation [GO:0010725]; regulation of protein localization [GO:0032880]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366] GO:0000122; GO:0000781; GO:0000785; GO:0000978; GO:0002039; GO:0002052; GO:0003682; GO:0003714; GO:0005634; GO:0005654; GO:0006357; GO:0006366; GO:0006482; GO:0010569; GO:0010725; GO:0010976; GO:0016491; GO:0016570; GO:0019899; GO:0021983; GO:0030154; GO:0030374; GO:0030851; GO:0031398; GO:0032091; GO:0032451; GO:0032452; GO:0032453; GO:0032454; GO:0032880; GO:0032991; GO:0033169; GO:0034644; GO:0034720; GO:0035563; GO:0043426; GO:0043433; GO:0043518; GO:0045648; GO:0045654; GO:0045793; GO:0045892; GO:0045944; GO:0046098; GO:0050660; GO:0050681; GO:0050767; GO:0050768; GO:0051091; GO:0051572; GO:0051573; GO:0055001; GO:0061629; GO:0061752; GO:0071480; GO:0090308; GO:0106222; GO:0120162; GO:0140297; GO:0140682; GO:0140861; GO:1902166; GO:1990138; GO:1990391; GO:1990841; GO:2000179; GO:2000648 37329 XM_044318650.1 110 16 36 47 77 O75899 3.46e-73 Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51) (HG20) Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway [GO:0007186]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; neuron-glial cell signaling [GO:0150099]; synaptic transmission, GABAergic [GO:0051932] GO:0004888; GO:0004965; GO:0005737; GO:0005886; GO:0007186; GO:0007193; GO:0007194; GO:0007214; GO:0007268; GO:0038039; GO:0043005; GO:0045211; GO:0046982; GO:0051932; GO:0150099; GO:1902710; GO:1902712 37330 XM_029331465.2 200 90 403 100 1118 NA NA NA NA NA NA 37331 XR_006392461.1 13 4 0 15 15 NA NA NA NA NA NA 37332 XM_044318065.1 308 340 164 246 323 NA NA NA NA NA NA 37333 XM_044328324.1 801 1450 730 4322 2147 Q5VV67 2.63e-22 Peroxisome proliferator-activated receptor gamma coactivator-related protein 1 (PGC-1-related coactivator) (PRC) Homo sapiens (Human) positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0003723; GO:0005634; GO:0005654; GO:0030374; GO:0045944; GO:0051091 37334 XM_044324644.1 17 0 27 22 0 A2AJ76 4.43e-27 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 37335 XM_029353101.2 90 14 47 20 113 NA NA NA NA NA NA 37336 XM_044309306.1 1 0 0 0 29 NA NA NA NA NA NA 37337 XM_029339434.2 595 484 290 551 613 NA NA NA NA NA NA 37338 XM_044312803.1 3065 1293 1477 1331 972 Q5R941 6.16e-29 Peptidyl-prolyl cis-trans isomerase FKBP14 (PPIase FKBP14) (EC 5.2.1.8) (FK506-binding protein 14) (FKBP-14) (Rotamase) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003755; GO:0005509; GO:0005788 37339 XR_006391729.1 90 110 44 136 45 NA NA NA NA NA NA 37340 XM_044324041.1 639 472 274 542 811 P09884 0 DNA polymerase alpha catalytic subunit (EC 2.7.7.7) (DNA polymerase alpha catalytic subunit p180) Homo sapiens (Human) DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication initiation [GO:0006270]; DNA replication, synthesis of RNA primer [GO:0006269]; DNA strand elongation involved in DNA replication [GO:0006271]; DNA synthesis involved in DNA repair [GO:0000731]; double-strand break repair via nonhomologous end joining [GO:0006303]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; mitotic DNA replication initiation [GO:1902975]; regulation of type I interferon production [GO:0032479] GO:0000166; GO:0000731; GO:0003677; GO:0003682; GO:0003688; GO:0003697; GO:0003887; GO:0005634; GO:0005635; GO:0005654; GO:0005658; GO:0005730; GO:0005829; GO:0006260; GO:0006269; GO:0006270; GO:0006271; GO:0006272; GO:0006273; GO:0006281; GO:0006303; GO:0008270; GO:0016363; GO:0019901; GO:0032479; GO:1902975 37341 XR_003823952.2 479 540 263 340 324 NA NA NA NA NA NA 37342 XM_044326142.1 8 0 0 67 3 NA NA NA NA NA NA 37343 XM_044318899.1 0 229 87 237 593 NA NA NA NA NA NA 37344 XM_029331485.2 867 982 443 849 860 Q8K4P0 0 pre-mRNA 3' end processing protein WDR33 (WD repeat-containing protein 33) (WD repeat-containing protein of 146 kDa) Mus musculus (Mouse) mRNA polyadenylation [GO:0006378] GO:0001650; GO:0005581; GO:0005634; GO:0005654; GO:0005847; GO:0006378 37345 XM_044323732.1 0 24 0 0 22 NA NA NA NA NA NA 37346 XM_044307183.1 8 4 1 5 0 NA NA NA NA NA NA 37347 XM_044314605.1 15 0 0 0 0 Q09575 3.71e-22 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 37348 XM_029328823.2 73 34 37 64 110 Q8HYJ5 3.23e-44 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3 (EC 2.4.1.65) (4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase) (EC 2.4.1.152) (Alpha-3-fucosyltransferase FUT3) (EC 2.4.1.-) (Alpha-3/4-fucosyltransferase) (Blood group Lewis alpha-4-fucosyltransferase) (Lewis FT) (Fucosyltransferase 3) (Fucosyltransferase III) (FucT-III) Pongo pygmaeus (Bornean orangutan) fucosylation [GO:0036065]; lipid metabolic process [GO:0006629]; oligosaccharide metabolic process [GO:0009311]; positive regulation of cell-cell adhesion [GO:0022409]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127] GO:0006487; GO:0006493; GO:0006629; GO:0009311; GO:0017060; GO:0017083; GO:0022409; GO:0030334; GO:0032580; GO:0036065; GO:0042127 37349 XM_029327219.2 325 531 412 387 203 Q5XIJ1 3.33e-89 Abasic site processing protein HMCES (Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein) (ES cell-specific 5hmC-binding protein) (Peptidase HMCES) (EC 3.4.-.-) (SRAP domain-containing protein 1) Rattus norvegicus (Rat) cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; positive regulation of isotype switching [GO:0045830]; protein-DNA covalent cross-linking [GO:0018142]; proteolysis [GO:0006508] GO:0003697; GO:0005657; GO:0006508; GO:0006974; GO:0008233; GO:0018142; GO:0045830; GO:0097681 37350 XM_029358489.2 69 89 15 13 24 Q9R0W9 1.77e-34 Neuronal acetylcholine receptor subunit alpha-6 Mus musculus (Mouse) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system process [GO:0050877]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of dopamine secretion [GO:0014059]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165] GO:0004888; GO:0005231; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0014059; GO:0016020; GO:0022848; GO:0030594; GO:0032991; GO:0034220; GO:0042391; GO:0042734; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051899; GO:0098691; GO:0099171; GO:1901363; GO:1904315 37351 XM_029340037.2 9182 9138 3538 6253 4464 P03967 1.51e-33 Ras-like protein rasD (EC 3.6.5.2) (Transforming protein p23 homolog) Dictyostelium discoideum (Social amoeba) adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway [GO:0140582]; chemotaxis [GO:0006935]; MAPK cascade [GO:0000165]; mitotic cytokinesis [GO:0000281]; phototaxis [GO:0042331]; Ras protein signal transduction [GO:0007265]; response to bacterium [GO:0009617]; thermotaxis [GO:0043052] GO:0000165; GO:0000281; GO:0003924; GO:0003925; GO:0004860; GO:0005525; GO:0005811; GO:0005829; GO:0005886; GO:0006935; GO:0007265; GO:0009617; GO:0019003; GO:0019887; GO:0042331; GO:0043052; GO:0140582 37352 XR_006391895.1 62 75 21 143 129 NA NA NA NA NA NA 37353 XM_044324046.1 239 0 0 0 23 D3ZZL9 5.82e-90 GRIP and coiled-coil domain-containing protein 2 (185 kDa Golgi coiled-coil protein) Rattus norvegicus (Rat) Golgi ribbon formation [GO:0090161]; late endosome to Golgi transport [GO:0034499]; microtubule anchoring [GO:0034453]; microtubule organizing center organization [GO:0031023]; protein localization to Golgi apparatus [GO:0034067]; protein targeting to lysosome [GO:0006622]; recycling endosome to Golgi transport [GO:0071955]; regulation of protein exit from endoplasmic reticulum [GO:0070861]; retrograde transport, endosome to Golgi [GO:0042147] GO:0005794; GO:0005802; GO:0005829; GO:0006622; GO:0016020; GO:0031023; GO:0034067; GO:0034453; GO:0034499; GO:0042147; GO:0042802; GO:0070861; GO:0071955; GO:0090161 37354 XR_006397700.1 0 0 0 0 11 NA NA NA NA NA NA 37355 XM_044325944.1 464 188 52 246 481 NA NA NA NA NA NA 37356 XM_044316504.1 1577 1464 785 1532 1460 NA NA NA NA NA NA 37357 XM_029328838.2 499 320 32 50 317 NA NA NA NA NA NA 37358 XM_029344314.2 229 143 95 181 333 Q15468 1.89e-72 SCL-interrupting locus protein (TAL-1-interrupting locus protein) Homo sapiens (Human) centrosome duplication [GO:0051298]; determination of left/right symmetry [GO:0007368]; embryonic axis specification [GO:0000578]; floor plate development [GO:0033504]; forebrain development [GO:0030900]; heart looping [GO:0001947]; in utero embryonic development [GO:0001701]; mitotic spindle organization [GO:0007052]; multicellular organism growth [GO:0035264]; negative regulation of apoptotic process [GO:0043066]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; notochord development [GO:0030903]; positive regulation of centriole replication [GO:0046601]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of spindle assembly [GO:1905832]; protein localization to centrosome [GO:0071539]; regulation of centriole replication [GO:0046599]; regulation of mitotic spindle organization [GO:0060236]; smoothened signaling pathway [GO:0007224] GO:0000578; GO:0001701; GO:0001843; GO:0001947; GO:0005737; GO:0005813; GO:0005814; GO:0005829; GO:0007052; GO:0007224; GO:0007368; GO:0021915; GO:0030900; GO:0030903; GO:0033504; GO:0035264; GO:0042802; GO:0043066; GO:0046599; GO:0046601; GO:0051298; GO:0060236; GO:0071539; GO:0120099; GO:1900087; GO:1905832 37359 XM_029326811.2 1 1 44 14 47 NA NA NA NA NA NA 37360 XM_044321872.1 543 333 313 267 135 Q23915 1.4e-28 Probable serine/threonine-protein kinase kinX (EC 2.7.11.1) Dictyostelium discoideum (Social amoeba) protein phosphorylation [GO:0006468]; signal transduction [GO:0007165] GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0006468; GO:0007165; GO:0106310 37361 XM_044326040.1 0 0 0 0 77 Q91175 4.68e-38 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (MAR1) Oryzias latipes (Japanese rice fish) (Japanese killifish) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of vasoconstriction [GO:0045907] GO:0001996; GO:0004930; GO:0004937; GO:0005886; GO:0007200; GO:0007204; GO:0007267; GO:0043410; GO:0045907; GO:0071880 37362 XM_029341078.2 1603 1416 908 2055 1483 Q9JK84 1.12e-99 Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A) Mus musculus (Mouse) cell division [GO:0051301]; centrosome cycle [GO:0007098]; establishment or maintenance of cell polarity [GO:0007163]; regulation of cellular localization [GO:0060341] GO:0005080; GO:0005634; GO:0005923; GO:0005938; GO:0007098; GO:0007163; GO:0016324; GO:0032991; GO:0051301; GO:0060341 37363 XM_029338168.2 611 269 179 283 531 A5PJ65 5.41e-72 Protein RER1 Bos taurus (Bovine) localization [GO:0051179] GO:0000139; GO:0051179 37364 XM_029331337.2 0 0 0 12 11 NA NA NA NA NA NA 37365 XM_044309738.1 34 18 33 32 85 NA NA NA NA NA NA 37366 XM_029355188.2 10024 9732 4857 16981 11479 P18654 0 Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (p90RSK3) (MAP kinase-activated protein kinase 1b) (MAPK-activated protein kinase 1b) (MAPKAP kinase 1b) (MAPKAPK-1b) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) Mus musculus (Mouse) cell cycle [GO:0007049]; intracellular signal transduction [GO:0035556]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to lipopolysaccharide [GO:0032496]; toll-like receptor signaling pathway [GO:0002224] GO:0000287; GO:0002224; GO:0004674; GO:0004711; GO:0005524; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0007049; GO:0018105; GO:0019901; GO:0032496; GO:0035556; GO:0043027; GO:0043154; GO:0045944; GO:0106310 37367 XM_044323533.1 56 52 50 0 0 NA NA NA NA NA NA 37368 XM_044327198.1 109 0 0 9 2 NA NA NA NA NA NA 37369 XM_044327060.1 608 270 253 393 415 Q9Y334 7.43e-22 von Willebrand factor A domain-containing protein 7 (Protein G7c) Homo sapiens (Human) NA GO:0005576 37370 XM_044327523.1 59 56 6 36 39 P27653 0 C-1-tetrahydrofolate synthase, cytoplasmic (C1-THF synthase) [Includes: Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9); Formyltetrahydrofolate synthetase (EC 6.3.4.3)] Rattus norvegicus (Rat) 10-formyltetrahydrofolate biosynthetic process [GO:0009257]; heart development [GO:0007507]; histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; methionine metabolic process [GO:0006555]; neural tube closure [GO:0001843]; neutrophil homeostasis [GO:0001780]; nucleotide metabolic process [GO:0009117]; one-carbon metabolic process [GO:0006730]; purine nucleotide biosynthetic process [GO:0006164]; purine ribonucleotide biosynthetic process [GO:0009152]; response to nitrogen dioxide [GO:0035713]; serine family amino acid biosynthetic process [GO:0009070]; serine family amino acid metabolic process [GO:0009069]; somite development [GO:0061053]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653]; transsulfuration [GO:0019346] GO:0000105; GO:0001780; GO:0001843; GO:0004329; GO:0004477; GO:0004486; GO:0004487; GO:0004488; GO:0005524; GO:0005737; GO:0005829; GO:0006164; GO:0006555; GO:0006730; GO:0007507; GO:0009069; GO:0009070; GO:0009086; GO:0009117; GO:0009152; GO:0009257; GO:0019346; GO:0035713; GO:0035999; GO:0046653; GO:0061053 37371 XR_006396196.1 6 0 0 0 11 NA NA NA NA NA NA 37372 XM_044319622.1 7 0 0 0 7 NA NA NA NA NA NA 37373 XM_029335432.2 103 247 80 329 91 Q6DC77 3.04e-47 Membrane progestin receptor gamma-B (mPR gamma-B) (Progestin and adipoQ receptor family member V-B) Danio rerio (Zebrafish) (Brachydanio rerio) oogenesis [GO:0048477] GO:0005496; GO:0016020; GO:0038023; GO:0048477 37374 XM_044310511.1 0 24 24 1 0 NA NA NA NA NA NA 37375 XM_044325593.1 43 28 9 28 14 NA NA NA NA NA NA 37376 XM_044318440.1 1 0 0 0 8 NA NA NA NA NA NA 37377 XM_044320208.1 45 7 91 0 261 NA NA NA NA NA NA 37378 XM_029349852.2 62 84 11 46 22 A4QND0 1.12e-23 Ubiquitin-like protein 4A Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) tail-anchored membrane protein insertion into ER membrane [GO:0071816] GO:0005634; GO:0005829; GO:0071816; GO:0071818 37379 XM_029335764.2 269 204 160 306 289 NA NA NA NA NA NA 37380 XR_006396610.1 31 38 70 19 319 NA NA NA NA NA NA 37381 XM_044315599.1 136 14 24 62 76 P22897 9.6e-39 Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0001618; GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 37382 XM_044315599.1 136 14 24 62 76 P22897 2.22e-36 Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0001618; GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 37383 XM_044315599.1 136 14 24 62 76 P22897 1.98e-27 Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0001618; GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 37384 XM_044315599.1 136 14 24 62 76 P22897 7.85e-27 Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0001618; GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 37385 XM_044315599.1 136 14 24 62 76 P22897 4.31e-26 Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0001618; GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 37386 XR_006395756.1 35 14 9 52 19 NA NA NA NA NA NA 37387 XM_044320151.1 736 560 422 571 461 P70531 7.7e-129 Eukaryotic elongation factor 2 kinase (eEF-2 kinase) (eEF-2K) (EC 2.7.11.20) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase) Rattus norvegicus (Rat) cellular response to anoxia [GO:0071454]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to insulin stimulus [GO:0032869]; negative regulation of apoptotic process [GO:0043066]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of endocytosis [GO:0045807]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; regulation of protein autophosphorylation [GO:0031952]; regulation of translation at postsynapse [GO:0140245]; response to ischemia [GO:0002931]; response to prolactin [GO:1990637] GO:0002931; GO:0004674; GO:0004686; GO:0005509; GO:0005516; GO:0005524; GO:0014069; GO:0031952; GO:0032869; GO:0043066; GO:0043197; GO:0045182; GO:0045807; GO:0046777; GO:0051965; GO:0061003; GO:0071277; GO:0071320; GO:0071454; GO:0098978; GO:0140245; GO:1990416; GO:1990637 37388 XM_044320151.1 736 560 422 571 461 P70531 9.29e-43 Eukaryotic elongation factor 2 kinase (eEF-2 kinase) (eEF-2K) (EC 2.7.11.20) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase) Rattus norvegicus (Rat) cellular response to anoxia [GO:0071454]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to insulin stimulus [GO:0032869]; negative regulation of apoptotic process [GO:0043066]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of endocytosis [GO:0045807]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; regulation of protein autophosphorylation [GO:0031952]; regulation of translation at postsynapse [GO:0140245]; response to ischemia [GO:0002931]; response to prolactin [GO:1990637] GO:0002931; GO:0004674; GO:0004686; GO:0005509; GO:0005516; GO:0005524; GO:0014069; GO:0031952; GO:0032869; GO:0043066; GO:0043197; GO:0045182; GO:0045807; GO:0046777; GO:0051965; GO:0061003; GO:0071277; GO:0071320; GO:0071454; GO:0098978; GO:0140245; GO:1990416; GO:1990637 37389 XM_044323892.1 483 6 32 55 7 Q86WI3 3.01e-23 Protein NLRC5 (Caterpiller protein 16.1) (CLR16.1) (Nucleotide-binding oligomerization domain protein 27) (Nucleotide-binding oligomerization domain protein 4) Homo sapiens (Human) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of type II interferon-mediated signaling pathway [GO:0060335]; regulation of kinase activity [GO:0043549]; response to bacterium [GO:0009617] GO:0000978; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0009617; GO:0032088; GO:0035556; GO:0043549; GO:0045087; GO:0045345; GO:0045944; GO:0051607; GO:0060335; GO:0060339; GO:0060340 37390 XR_006392135.1 3 0 7 5 11 NA NA NA NA NA NA 37391 XM_044315567.1 65 17 19 0 19 NA NA NA NA NA NA 37392 XM_029333489.2 852 669 495 1507 739 Q90Y54 0 Protein jagged-1b (Jagged1b) (Jagged3) Danio rerio (Zebrafish) (Brachydanio rerio) auditory receptor cell development [GO:0060117]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; cranial skeletal system development [GO:1904888]; dorsal/ventral pattern formation [GO:0009953]; exocrine pancreas development [GO:0031017]; face morphogenesis [GO:0060325]; fin regeneration [GO:0031101]; inner ear morphogenesis [GO:0042472]; intrahepatic bile duct development [GO:0035622]; liver development [GO:0001889]; Notch signaling pathway [GO:0007219]; otolith morphogenesis [GO:0032474]; pancreas development [GO:0031016]; semicircular canal development [GO:0060872]; semicircular canal morphogenesis [GO:0048752]; thyroid gland development [GO:0030878] GO:0001889; GO:0005112; GO:0005509; GO:0005886; GO:0007219; GO:0009953; GO:0030878; GO:0031016; GO:0031017; GO:0031101; GO:0032474; GO:0035622; GO:0042472; GO:0048752; GO:0060117; GO:0060325; GO:0060351; GO:0060872; GO:1904888 37393 XM_029333489.2 852 669 495 1507 739 Q90Y54 6.84e-164 Protein jagged-1b (Jagged1b) (Jagged3) Danio rerio (Zebrafish) (Brachydanio rerio) auditory receptor cell development [GO:0060117]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; cranial skeletal system development [GO:1904888]; dorsal/ventral pattern formation [GO:0009953]; exocrine pancreas development [GO:0031017]; face morphogenesis [GO:0060325]; fin regeneration [GO:0031101]; inner ear morphogenesis [GO:0042472]; intrahepatic bile duct development [GO:0035622]; liver development [GO:0001889]; Notch signaling pathway [GO:0007219]; otolith morphogenesis [GO:0032474]; pancreas development [GO:0031016]; semicircular canal development [GO:0060872]; semicircular canal morphogenesis [GO:0048752]; thyroid gland development [GO:0030878] GO:0001889; GO:0005112; GO:0005509; GO:0005886; GO:0007219; GO:0009953; GO:0030878; GO:0031016; GO:0031017; GO:0031101; GO:0032474; GO:0035622; GO:0042472; GO:0048752; GO:0060117; GO:0060325; GO:0060351; GO:0060872; GO:1904888 37394 XM_044310922.1 0 0 6 0 0 NA NA NA NA NA NA 37395 XM_029356362.2 7261 5307 3138 6592 5212 P26630 4.09e-86 Paired box protein Pax-6 (Pax[Zf-a]) Danio rerio (Zebrafish) (Brachydanio rerio) anatomical structure development [GO:0048856]; anterior/posterior pattern specification [GO:0009952]; epithalamus development [GO:0021538]; forebrain development [GO:0030900]; habenula development [GO:0021986]; hindbrain development [GO:0030902]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression [GO:0010468]; regulation of transcription by RNA polymerase II [GO:0006357]; retinal cone cell differentiation [GO:0042670]; retinal rod cell differentiation [GO:0060221] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0008284; GO:0009952; GO:0010468; GO:0021538; GO:0021986; GO:0030900; GO:0030902; GO:0042670; GO:0043565; GO:0045944; GO:0048856; GO:0060221 37396 XM_029325591.2 531 437 278 305 294 NA NA NA NA NA NA 37397 XM_029334178.2 40 0 0 0 0 NA NA NA NA NA NA 37398 XM_044317424.1 1175 918 825 1276 1182 NA NA NA NA NA NA 37399 XM_029329393.2 255 184 135 227 267 Q6P859 1.29e-46 G patch domain-containing protein 4 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0003676 37400 XM_029335728.2 151 111 95 113 178 NA NA NA NA NA NA 37401 XR_006395129.1 14 17 19 17 54 NA NA NA NA NA NA 37402 XM_044308562.1 40 14 33 56 51 NA NA NA NA NA NA 37403 XM_044316653.1 9 1 11 3 9 P29274 1.17e-22 Adenosine receptor A2a Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; astrocyte activation [GO:0048143]; blood circulation [GO:0008015]; blood coagulation [GO:0007596]; cell-cell signaling [GO:0007267]; cellular defense response [GO:0006968]; central nervous system development [GO:0007417]; eating behavior [GO:0042755]; excitatory postsynaptic potential [GO:0060079]; G protein-coupled adenosine receptor signaling pathway [GO:0001973]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; inhibitory postsynaptic potential [GO:0060080]; locomotory behavior [GO:0007626]; membrane depolarization [GO:0051899]; negative regulation of alpha-beta T cell activation [GO:0046636]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of inflammatory response [GO:0050728]; negative regulation of locomotion [GO:0040013]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of vascular permeability [GO:0043116]; neuron projection morphogenesis [GO:0048812]; phagocytosis [GO:0006909]; positive regulation of acetylcholine secretion, neurotransmission [GO:0014057]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of circadian sleep/wake cycle, sleep [GO:0045938]; positive regulation of glutamate secretion [GO:0014049]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of protein secretion [GO:0050714]; positive regulation of renal sodium excretion [GO:0035815]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of urine volume [GO:0035810]; prepulse inhibition [GO:0060134]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; regulation of calcium ion transport [GO:0051924]; regulation of DNA-templated transcription [GO:0006355]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of norepinephrine secretion [GO:0014061]; response to amphetamine [GO:0001975]; response to caffeine [GO:0031000]; response to inorganic substance [GO:0010035]; response to purine-containing compound [GO:0014074]; response to xenobiotic stimulus [GO:0009410]; sensory perception [GO:0007600]; synaptic transmission, cholinergic [GO:0007271]; synaptic transmission, dopaminergic [GO:0001963]; synaptic transmission, glutamatergic [GO:0035249]; vasodilation [GO:0042311] GO:0001609; GO:0001963; GO:0001973; GO:0001975; GO:0004930; GO:0005882; GO:0005886; GO:0006355; GO:0006469; GO:0006909; GO:0006915; GO:0006954; GO:0006968; GO:0007186; GO:0007188; GO:0007189; GO:0007205; GO:0007267; GO:0007271; GO:0007417; GO:0007596; GO:0007600; GO:0007626; GO:0008015; GO:0008285; GO:0008289; GO:0009410; GO:0010035; GO:0012505; GO:0014049; GO:0014057; GO:0014061; GO:0014069; GO:0014074; GO:0016020; GO:0019899; GO:0030425; GO:0030673; GO:0031000; GO:0031802; GO:0032230; GO:0035249; GO:0035810; GO:0035815; GO:0040013; GO:0042311; GO:0042734; GO:0042755; GO:0042802; GO:0043025; GO:0043116; GO:0043154; GO:0043524; GO:0044877; GO:0045211; GO:0045938; GO:0046636; GO:0048143; GO:0048786; GO:0048812; GO:0050714; GO:0050728; GO:0051393; GO:0051881; GO:0051899; GO:0051924; GO:0051968; GO:0060079; GO:0060080; GO:0060134; GO:0097190; GO:0098978; GO:0099171; GO:1900273; GO:2001235 37404 XM_044321674.1 25 0 0 0 0 P35439 5.5e-53 Glutamate receptor ionotropic, NMDA 1 (GluN1) (Glutamate [NMDA] receptor subunit zeta-1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1) Rattus norvegicus (Rat) adult locomotory behavior [GO:0008344]; associative learning [GO:0008306]; calcium ion homeostasis [GO:0055074]; calcium ion transmembrane import into cytosol [GO:0097553]; calcium ion transport [GO:0006816]; cation transmembrane transport [GO:0098655]; cation transport [GO:0006812]; cellular calcium ion homeostasis [GO:0006874]; cellular response to manganese ion [GO:0071287]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; conditioned taste aversion [GO:0001661]; excitatory postsynaptic potential [GO:0060079]; ionotropic glutamate receptor signaling pathway [GO:0035235]; learning [GO:0007612]; learning or memory [GO:0007611]; long-term memory [GO:0007616]; male mating behavior [GO:0060179]; memory [GO:0007613]; negative regulation of neuron apoptotic process [GO:0043524]; neuromuscular process [GO:0050905]; neuron cellular homeostasis [GO:0070050]; olfactory learning [GO:0008355]; pons maturation [GO:0021586]; positive regulation of apoptotic process [GO:0043065]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of cell death [GO:0010942]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of dendritic spine maintenance [GO:1902952]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of Schwann cell migration [GO:1900149]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; prepulse inhibition [GO:0060134]; propylene metabolic process [GO:0018964]; protein heterotetramerization [GO:0051290]; protein localization to postsynaptic membrane [GO:1903539]; protein-containing complex assembly [GO:0065003]; regulation of axonogenesis [GO:0050770]; regulation of cation transmembrane transport [GO:1904062]; regulation of cell communication [GO:0010646]; regulation of dendrite morphogenesis [GO:0048814]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of membrane potential [GO:0042391]; regulation of neuron apoptotic process [GO:0043523]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of respiratory gaseous exchange [GO:0043576]; regulation of synapse assembly [GO:0051963]; regulation of synaptic plasticity [GO:0048167]; response to amine [GO:0014075]; response to amphetamine [GO:0001975]; response to calcium ion [GO:0051592]; response to ethanol [GO:0045471]; response to fungicide [GO:0060992]; response to glycine [GO:1905429]; response to morphine [GO:0043278]; response to organic cyclic compound [GO:0014070]; rhythmic process [GO:0048511]; sensory perception of pain [GO:0019233]; social behavior [GO:0035176]; startle response [GO:0001964]; suckling behavior [GO:0001967]; synaptic transmission, glutamatergic [GO:0035249]; transcription by RNA polymerase II [GO:0006366]; visual learning [GO:0008542] GO:0001540; GO:0001661; GO:0001964; GO:0001967; GO:0001975; GO:0004970; GO:0004972; GO:0005102; GO:0005261; GO:0005262; GO:0005509; GO:0005516; GO:0005737; GO:0005783; GO:0005789; GO:0005886; GO:0006366; GO:0006812; GO:0006816; GO:0006874; GO:0007268; GO:0007611; GO:0007612; GO:0007613; GO:0007616; GO:0008021; GO:0008306; GO:0008344; GO:0008355; GO:0008542; GO:0009986; GO:0010524; GO:0010646; GO:0010942; GO:0014069; GO:0014070; GO:0014075; GO:0015276; GO:0016020; GO:0016594; GO:0016595; GO:0017146; GO:0018964; GO:0019233; GO:0019899; GO:0019902; GO:0021586; GO:0021987; GO:0022843; GO:0022849; GO:0030425; GO:0030672; GO:0032590; GO:0035176; GO:0035235; GO:0035249; GO:0035254; GO:0038023; GO:0042165; GO:0042391; GO:0042734; GO:0043005; GO:0043025; GO:0043065; GO:0043083; GO:0043195; GO:0043197; GO:0043278; GO:0043523; GO:0043524; GO:0043576; GO:0044307; GO:0044877; GO:0045202; GO:0045211; GO:0045471; GO:0045944; GO:0048167; GO:0048168; GO:0048169; GO:0048511; GO:0048787; GO:0048814; GO:0050770; GO:0050905; GO:0051290; GO:0051592; GO:0051963; GO:0051968; GO:0055074; GO:0060076; GO:0060079; GO:0060134; GO:0060179; GO:0060992; GO:0065003; GO:0070050; GO:0071287; GO:0097060; GO:0097553; GO:0098655; GO:0098686; GO:0098688; GO:0098839; GO:0098978; GO:0099507; GO:1900149; GO:1902952; GO:1903428; GO:1903539; GO:1904062; GO:1904315; GO:1905429; GO:2000463; GO:2001056 37405 XR_006392306.1 0 15 0 7 22 NA NA NA NA NA NA 37406 XM_044314033.1 100 72 116 92 138 NA NA NA NA NA NA 37407 XM_029331534.2 54 17 28 13 80 NA NA NA NA NA NA 37408 XM_044312485.1 200 359 207 65 206 G3V9H8 2.82e-81 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Rattus norvegicus (Rat) cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0007156; GO:0007158; GO:0007169; GO:0007399; GO:0009410; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030182; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0098797 37409 XM_044312002.1 2 61 0 0 4 NA NA NA NA NA NA 37410 XM_029338820.2 28 2 12 23 12 B3EWZ7 9.51e-79 Threonine-rich protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 37411 XR_003827302.2 554 554 280 358 408 NA NA NA NA NA NA 37412 XM_044308353.1 7 32 16 76 17 NA NA NA NA NA NA 37413 XM_044313815.1 4 0 0 11 41 Q15485 7.68e-79 Ficolin-2 (37 kDa elastin-binding protein) (Collagen/fibrinogen domain-containing protein 2) (EBP-37) (Ficolin-B) (Ficolin-beta) (Hucolin) (L-ficolin) (Serum lectin p35) Homo sapiens (Human) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; positive regulation of opsonization [GO:1903028]; proteolysis [GO:0006508]; recognition of apoptotic cell [GO:0043654] GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005576; GO:0005581; GO:0005615; GO:0006508; GO:0008228; GO:0009897; GO:0042802; GO:0043394; GO:0043654; GO:0046872; GO:0048306; GO:0050829; GO:0050830; GO:0062023; GO:0070062; GO:0072562; GO:0097367; GO:1903028; GO:1905370; GO:2001065 37414 XM_044315422.1 171 96 55 99 219 NA NA NA NA NA NA 37415 XR_006396304.1 123 125 66 163 179 NA NA NA NA NA NA 37416 XR_006392799.1 0 0 174 0 555 NA NA NA NA NA NA 37417 XM_029334422.2 13 0 60 20 0 Q91981 1.67e-32 Homeobox protein OTX2 (zOTX2) (Orthodenticle homolog 2) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to alcohol [GO:0097306]; cerebellum development [GO:0021549]; hindbrain development [GO:0030902]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; regulation of transcription by RNA polymerase II [GO:0006357]; retinal pigment epithelium development [GO:0003406] GO:0000978; GO:0000981; GO:0003406; GO:0005634; GO:0006357; GO:0021549; GO:0030901; GO:0030902; GO:0030917; GO:0097306 37418 XM_044318198.1 0 904 604 354 164 NA NA NA NA NA NA 37419 XM_044308473.1 8 42 22 39 67 NA NA NA NA NA NA 37420 XM_029335700.2 90 0 0 0 0 B3DLH6 0 Myoferlin (Fer-1-like protein 3) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) plasma membrane repair [GO:0001778] GO:0001778; GO:0005543; GO:0005901; GO:0030659; GO:0031965; GO:0046872 37421 XM_029351964.2 37664 21508 21070 36320 24621 P29773 2.14e-36 Protein C-ets-2 Lytechinus variegatus (Green sea urchin) (Echinus variegatus) regulation of transcription by RNA polymerase II [GO:0006357] GO:0003700; GO:0005634; GO:0006357; GO:0043565 37422 XR_003828480.2 75 40 75 80 111 NA NA NA NA NA NA 37423 XM_044321353.1 576 0 151 30 0 Q96PY6 1.33e-145 Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase 1) (NimA-related protein kinase 1) (Renal carcinoma antigen NY-REN-55) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; cilium assembly [GO:0060271]; protein phosphorylation [GO:0006468] GO:0000242; GO:0004672; GO:0004674; GO:0004713; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0005829; GO:0006468; GO:0007049; GO:0016301; GO:0034451; GO:0046872; GO:0051301; GO:0060271; GO:0071889; GO:0106310 37424 XR_003824176.2 223 45 81 196 151 NA NA NA NA NA NA 37425 XR_006393245.1 0 9 5 7 0 NA NA NA NA NA NA 37426 XM_029336287.2 1034 876 612 865 999 Q9BW91 8.23e-107 ADP-ribose pyrophosphatase, mitochondrial (EC 3.6.1.13) (ADP-ribose diphosphatase) (ADP-ribose phosphohydrolase) (Adenosine diphosphoribose pyrophosphatase) (ADPR-PPase) (Nucleoside diphosphate-linked moiety X motif 9) (Nudix motif 9) Homo sapiens (Human) ADP catabolic process [GO:0046032]; IDP catabolic process [GO:0046709]; nucleobase-containing small molecule metabolic process [GO:0055086] GO:0005739; GO:0005759; GO:0016604; GO:0019144; GO:0030054; GO:0031965; GO:0046032; GO:0046709; GO:0047631; GO:0055086; GO:0070062 37427 XM_029355719.2 9 0 36 0 50 Q9D2E1 1.93e-87 Testis-specific serine/threonine-protein kinase 3 (TSK-3) (TSSK-3) (Testis-specific kinase 3) (EC 2.7.11.1) (Serine/threonine-protein kinase 22C) Mus musculus (Mouse) intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]; sperm capacitation [GO:0048240]; spermatogenesis [GO:0007283] GO:0000287; GO:0004674; GO:0005524; GO:0006468; GO:0007283; GO:0035556; GO:0048240; GO:0106310 37428 XM_044323385.1 1 68 22 64 19 NA NA NA NA NA NA 37429 XR_003825362.2 28 0 21 22 6 Q9Z1N6 5.73e-27 Secreted frizzled-related sequence protein 4 (FRP-4) (sFRP-4) Mus musculus (Mouse) bone morphogenesis [GO:0060349]; canonical Wnt signaling pathway [GO:0060070]; cell differentiation [GO:0030154]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of JNK cascade [GO:0046329]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of sodium-dependent phosphate transport [GO:2000119]; phosphate ion homeostasis [GO:0055062]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of epidermal cell differentiation [GO:0045606]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of receptor internalization [GO:0002092]; regulation of BMP signaling pathway [GO:0030510] GO:0002092; GO:0005615; GO:0005634; GO:0005737; GO:0008285; GO:0009986; GO:0010628; GO:0017147; GO:0030154; GO:0030510; GO:0043065; GO:0043433; GO:0045606; GO:0046329; GO:0055062; GO:0060070; GO:0060349; GO:0090090; GO:0090263; GO:1902174; GO:2000051; GO:2000119 37430 XM_029352328.2 365 116 166 229 31 Q94B65 1.06e-44 UDP-galactose/UDP-glucose transporter 7 (AtUTr7) Arabidopsis thaliana (Mouse-ear cress) carbohydrate transport [GO:0008643]; lateral root development [GO:0048527]; root hair cell development [GO:0080147]; UDP-galactose transmembrane transport [GO:0072334]; UDP-glucose transmembrane transport [GO:0015786] GO:0000139; GO:0005459; GO:0005460; GO:0005794; GO:0008643; GO:0015297; GO:0015786; GO:0048527; GO:0072334; GO:0080147 37431 XR_006394760.1 283 296 356 189 786 NA NA NA NA NA NA 37432 XM_029328857.2 0 8 0 25 0 Q68CZ6 1.16e-43 HAUS augmin-like complex subunit 3 Homo sapiens (Human) cell division [GO:0051301]; centrosome cycle [GO:0007098]; spindle assembly [GO:0051225] GO:0005813; GO:0005829; GO:0007098; GO:0051225; GO:0051301; GO:0070652; GO:0072686; GO:1990498 37433 XM_044328444.1 14 60 497 975 22 NA NA NA NA NA NA 37434 XM_029333875.2 2297 2479 1006 2251 2277 Q96PX1 1.85e-103 E3 ubiquitin ligase RNF157 (EC 2.3.2.27) (RING finger protein 157) (RING-type E3 ubiquitin transferase RNF157) Homo sapiens (Human) endosome to lysosome transport [GO:0008333]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; positive regulation of dendrite extension [GO:1903861]; protein autoubiquitination [GO:0051865]; protein ubiquitination [GO:0016567] GO:0005634; GO:0005737; GO:0005769; GO:0005886; GO:0008333; GO:0016567; GO:0043066; GO:0043951; GO:0044297; GO:0045744; GO:0046872; GO:0051865; GO:0061630; GO:1903861 37435 XM_029344751.2 14 27 16 31 20 P56718 4.15e-27 Orexin/Hypocretin receptor type 1 (Hypocretin receptor type 1) (Orexin receptor type 1) (Ox-1-R) (Ox1-R) (Ox1R) Rattus norvegicus (Rat) feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0004930; GO:0005886; GO:0007186; GO:0007218; GO:0007631; GO:0016499; GO:0017046; GO:0051480; GO:0070374 37436 XM_044311630.1 109 16 203 28 268 NA NA NA NA NA NA 37437 XM_029331560.2 0 0 68 0 0 Q5RAM2 3.73e-58 Estrogen-related receptor gamma (Estrogen receptor-related protein 3) (Nuclear receptor subfamily 3 group B member 3) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) regulation of DNA-templated transcription [GO:0006355]; retinoic acid receptor signaling pathway [GO:0048384] GO:0003707; GO:0004879; GO:0005496; GO:0005654; GO:0006355; GO:0008270; GO:0043565; GO:0048384 37438 XR_006395182.1 3 28 10 0 12 NA NA NA NA NA NA 37439 XM_044306885.1 55 34 20 12 48 NA NA NA NA NA NA 37440 XM_029337381.2 5319 14394 3147 9299 4272 Q7ZUB2 1.86e-73 40S ribosomal protein S17 Coturnix japonica (Japanese quail) (Coturnix coturnix japonica) translation [GO:0006412] GO:0003735; GO:0005840; GO:0006412; GO:1990904 37441 XM_044319131.1 37 31 2 50 21 NA NA NA NA NA NA 37442 XM_044320114.1 0 3 0 8 1 O14718 2.31e-27 Visual pigment-like receptor peropsin Homo sapiens (Human) cellular response to light stimulus [GO:0071482]; G protein-coupled receptor signaling pathway [GO:0007186]; phototransduction [GO:0007602]; visual perception [GO:0007601] GO:0001750; GO:0004930; GO:0005886; GO:0007186; GO:0007601; GO:0007602; GO:0008020; GO:0071482 37443 XM_029340968.2 406 490 241 320 258 P0AF48 1.18e-46 UPF0047 protein YjbQ Escherichia coli (strain K12) NA NA 37444 XR_003828646.2 304 154 196 236 194 NA NA NA NA NA NA 37445 XM_029345050.2 893 566 501 471 714 Q8TCT0 5.86e-121 Ceramide kinase (hCERK) (EC 2.7.1.138) (Acylsphingosine kinase) (Lipid kinase 4) (LK4) Homo sapiens (Human) ceramide metabolic process [GO:0006672]; glycosphingolipid metabolic process [GO:0006687]; phosphorylation [GO:0016310]; sphingolipid metabolic process [GO:0006665] GO:0000287; GO:0001727; GO:0001729; GO:0005524; GO:0005737; GO:0005886; GO:0006665; GO:0006672; GO:0006687; GO:0016020; GO:0016310; GO:0102773 37446 XM_029332801.2 0 0 19 0 84 Q9I8C7 1.02e-95 Neuronal acetylcholine receptor subunit alpha-10 (Alpha 10 nAChR) (Nicotinic acetylcholine receptor subunit alpha-10) (NACHR alpha-10) Gallus gallus (Chicken) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; response to auditory stimulus [GO:0010996]; signal transduction [GO:0007165] GO:0004888; GO:0005231; GO:0005262; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0010996; GO:0022848; GO:0030594; GO:0034220; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051899; GO:1904315 37447 XR_006397191.1 7786 10677 4564 6550 3636 NA NA NA NA NA NA 37448 XM_044320951.1 13 6 20 36 24 D3Z5L6 4e-44 MFS-type transporter SLC18B1 (Solute carrier family 18 member B1) (Vesicular polyamine transporter) (VPAT) Mus musculus (Mouse) serotonin transport [GO:0006837]; serotonin uptake [GO:0051610]; spermidine transport [GO:0015848]; spermine transport [GO:0000296] GO:0000296; GO:0006837; GO:0015311; GO:0015312; GO:0015848; GO:0022857; GO:0030667; GO:0030672; GO:0051610 37449 XM_044325120.1 3 0 7 0 12 NA NA NA NA NA NA 37450 XM_029352643.2 63 7 49 185 253 NA NA NA NA NA NA 37451 XM_044314757.1 0 7 12 31 3 Q9UBN7 2.18e-42 Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-) Homo sapiens (Human) aggresome assembly [GO:0070842]; autophagy [GO:0006914]; axonal transport of mitochondrion [GO:0019896]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to misfolded protein [GO:0071218]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to topologically incorrect protein [GO:0035967]; cilium assembly [GO:0060271]; cilium disassembly [GO:0061523]; collateral sprouting [GO:0048668]; dendritic spine morphogenesis [GO:0060997]; epigenetic regulation of gene expression [GO:0040029]; histone deacetylation [GO:0016575]; Hsp90 deacetylation [GO:0070846]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of protein-containing complex disassembly [GO:0043242]; negative regulation of proteolysis [GO:0045861]; negative regulation of transcription by RNA polymerase II [GO:0000122]; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:0061734]; peptidyl-lysine deacetylation [GO:0034983]; polyubiquitinated misfolded protein transport [GO:0070845]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of hydrogen peroxide-mediated programmed cell death [GO:1901300]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of tubulin deacetylation [GO:0090044]; protein deacetylation [GO:0006476]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; protein-containing complex disassembly [GO:0032984]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of autophagy [GO:0010506]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of establishment of protein localization [GO:0070201]; regulation of fat cell differentiation [GO:0045598]; regulation of macroautophagy [GO:0016241]; regulation of microtubule-based movement [GO:0060632]; regulation of protein stability [GO:0031647]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]; response to dexamethasone [GO:0071548]; response to growth factor [GO:0070848]; response to immobilization stress [GO:0035902]; response to misfolded protein [GO:0051788]; tubulin deacetylation [GO:0090042]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] GO:0000118; GO:0000122; GO:0000209; GO:0000978; GO:0001222; GO:0001975; GO:0003779; GO:0004407; GO:0005634; GO:0005654; GO:0005737; GO:0005771; GO:0005813; GO:0005829; GO:0005874; GO:0005875; GO:0005901; GO:0006476; GO:0006515; GO:0006886; GO:0006914; GO:0007026; GO:0008013; GO:0008017; GO:0008270; GO:0010506; GO:0010634; GO:0010727; GO:0016234; GO:0016235; GO:0016241; GO:0016575; GO:0019896; GO:0019899; GO:0030424; GO:0030425; GO:0031252; GO:0031333; GO:0031593; GO:0031625; GO:0031647; GO:0031648; GO:0032418; GO:0032984; GO:0033138; GO:0033558; GO:0034983; GO:0035902; GO:0035967; GO:0036064; GO:0040029; GO:0042826; GO:0042903; GO:0043014; GO:0043130; GO:0043162; GO:0043204; GO:0043242; GO:0045598; GO:0045861; GO:0045892; GO:0048156; GO:0048471; GO:0048487; GO:0048668; GO:0048843; GO:0050775; GO:0051354; GO:0051412; GO:0051787; GO:0051788; GO:0051879; GO:0051968; GO:0060271; GO:0060632; GO:0060765; GO:0060997; GO:0061523; GO:0061734; GO:0070201; GO:0070301; GO:0070840; GO:0070842; GO:0070845; GO:0070846; GO:0070848; GO:0071218; GO:0071374; GO:0071548; GO:0090042; GO:0090044; GO:1901300; GO:1901984; GO:1903146; GO:1903223; GO:1904056; GO:1904115; GO:2000273 37452 XM_044314757.1 0 7 12 31 3 Q9UBN7 2.14e-36 Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-) Homo sapiens (Human) aggresome assembly [GO:0070842]; autophagy [GO:0006914]; axonal transport of mitochondrion [GO:0019896]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to misfolded protein [GO:0071218]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to topologically incorrect protein [GO:0035967]; cilium assembly [GO:0060271]; cilium disassembly [GO:0061523]; collateral sprouting [GO:0048668]; dendritic spine morphogenesis [GO:0060997]; epigenetic regulation of gene expression [GO:0040029]; histone deacetylation [GO:0016575]; Hsp90 deacetylation [GO:0070846]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of protein-containing complex disassembly [GO:0043242]; negative regulation of proteolysis [GO:0045861]; negative regulation of transcription by RNA polymerase II [GO:0000122]; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:0061734]; peptidyl-lysine deacetylation [GO:0034983]; polyubiquitinated misfolded protein transport [GO:0070845]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of hydrogen peroxide-mediated programmed cell death [GO:1901300]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of tubulin deacetylation [GO:0090044]; protein deacetylation [GO:0006476]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; protein-containing complex disassembly [GO:0032984]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of autophagy [GO:0010506]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of establishment of protein localization [GO:0070201]; regulation of fat cell differentiation [GO:0045598]; regulation of macroautophagy [GO:0016241]; regulation of microtubule-based movement [GO:0060632]; regulation of protein stability [GO:0031647]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]; response to dexamethasone [GO:0071548]; response to growth factor [GO:0070848]; response to immobilization stress [GO:0035902]; response to misfolded protein [GO:0051788]; tubulin deacetylation [GO:0090042]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] GO:0000118; GO:0000122; GO:0000209; GO:0000978; GO:0001222; GO:0001975; GO:0003779; GO:0004407; GO:0005634; GO:0005654; GO:0005737; GO:0005771; GO:0005813; GO:0005829; GO:0005874; GO:0005875; GO:0005901; GO:0006476; GO:0006515; GO:0006886; GO:0006914; GO:0007026; GO:0008013; GO:0008017; GO:0008270; GO:0010506; GO:0010634; GO:0010727; GO:0016234; GO:0016235; GO:0016241; GO:0016575; GO:0019896; GO:0019899; GO:0030424; GO:0030425; GO:0031252; GO:0031333; GO:0031593; GO:0031625; GO:0031647; GO:0031648; GO:0032418; GO:0032984; GO:0033138; GO:0033558; GO:0034983; GO:0035902; GO:0035967; GO:0036064; GO:0040029; GO:0042826; GO:0042903; GO:0043014; GO:0043130; GO:0043162; GO:0043204; GO:0043242; GO:0045598; GO:0045861; GO:0045892; GO:0048156; GO:0048471; GO:0048487; GO:0048668; GO:0048843; GO:0050775; GO:0051354; GO:0051412; GO:0051787; GO:0051788; GO:0051879; GO:0051968; GO:0060271; GO:0060632; GO:0060765; GO:0060997; GO:0061523; GO:0061734; GO:0070201; GO:0070301; GO:0070840; GO:0070842; GO:0070845; GO:0070846; GO:0070848; GO:0071218; GO:0071374; GO:0071548; GO:0090042; GO:0090044; GO:1901300; GO:1901984; GO:1903146; GO:1903223; GO:1904056; GO:1904115; GO:2000273 37453 XR_006392435.1 53 50 38 42 23 NA NA NA NA NA NA 37454 XR_006391685.1 26 14 37 16 7 NA NA NA NA NA NA 37455 XM_044314454.1 381 950 405 604 561 P34334 1.26e-48 60S ribosomal protein L21 Caenorhabditis elegans translation [GO:0006412] GO:0003735; GO:0006412; GO:0022625 37456 XM_029346010.2 4 3 6 8 15 Q5ZI69 7.67e-33 39S ribosomal protein L37, mitochondrial (L37mt) (MRP-L37) Gallus gallus (Chicken) translation [GO:0006412] GO:0003735; GO:0005739; GO:0005743; GO:0005762; GO:0006412 37457 XR_003824612.2 13 0 0 0 0 NA NA NA NA NA NA 37458 XM_029328724.2 84 7 5 56 191 O88845 1.4e-84 A-kinase anchor protein 10, mitochondrial (AKAP-10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2) (Protein kinase A-anchoring protein 10) (PRKA10) Mus musculus (Mouse) protein localization [GO:0008104] GO:0005739; GO:0005829; GO:0005886; GO:0008104; GO:0032991; GO:0051018 37459 XR_003824019.2 27 33 31 78 49 NA NA NA NA NA NA 37460 XM_029344888.2 83 281 148 334 149 Q56A06 0 Protein O-mannosyl-transferase TMTC2 (EC 2.4.1.109) (Transmembrane and TPR repeat-containing protein 2) Mus musculus (Mouse) calcium ion homeostasis [GO:0055074]; protein O-linked mannosylation [GO:0035269] GO:0000030; GO:0004169; GO:0005783; GO:0005789; GO:0035269; GO:0055074 37461 XM_044309574.1 20 2 4 0 1 NA NA NA NA NA NA 37462 XM_044318732.1 138 28 79 86 283 NA NA NA NA NA NA 37463 XR_006397012.1 76 12 15 73 9 Q3YEC7 1.35e-86 Rab-like protein 6 (GTP-binding protein Parf) (Partner of ARF) (Rab-like protein 1) (RBEL1) Homo sapiens (Human) NA GO:0003924; GO:0005525; GO:0005634; GO:0005737; GO:0005813; GO:0005829 37464 XM_029348239.2 1840 1136 1364 1904 1510 Q5BKC9 4.55e-92 Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor) Rattus norvegicus (Rat) activation of GTPase activity [GO:0090630]; cell differentiation [GO:0030154]; ephrin receptor signaling pathway [GO:0048013]; negative regulation of dendritic spine morphogenesis [GO:0061002]; nervous system development [GO:0007399]; regulation of GTPase activity [GO:0043087]; regulation of synapse pruning [GO:1905806]; synapse pruning [GO:0098883] GO:0005085; GO:0005737; GO:0007399; GO:0016020; GO:0030154; GO:0030426; GO:0043087; GO:0046875; GO:0048013; GO:0061002; GO:0090630; GO:0098794; GO:0098883; GO:0098978; GO:1905806 37465 XM_029338267.2 5209 5246 3522 4991 5929 NA NA NA NA NA NA 37466 XM_029350743.2 6 13 3 2 56 NA NA NA NA NA NA 37467 XM_029337047.2 111 0 0 22 97 NA NA NA NA NA NA 37468 XM_044329310.1 0 3 0 53 1 NA NA NA NA NA NA 37469 XR_006393705.1 41 43 32 20 178 NA NA NA NA NA NA 37470 XM_029335270.2 86 0 0 0 0 NA NA NA NA NA NA 37471 XM_029332661.2 1046 634 545 1110 1215 NA NA NA NA NA NA 37472 XM_029324372.2 10 0 0 1 2 NA NA NA NA NA NA 37473 XM_029338869.2 1300 1487 515 2189 1800 P97401 1.55e-28 Secreted frizzled-related protein 3 (sFRP-3) (Frezzled) (Fritz) (Frizzled-related protein 1) (FrzB-1) Mus musculus (Mouse) canonical Wnt signaling pathway [GO:0060070]; cochlea morphogenesis [GO:0090103]; convergent extension involved in organogenesis [GO:0060029]; epithelial cell development [GO:0002064]; hepatocyte differentiation [GO:0070365]; inner ear morphogenesis [GO:0042472]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cartilage development [GO:0061037]; negative regulation of cell development [GO:0010721]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of hepatocyte differentiation [GO:0070367]; negative regulation of Wnt signaling pathway [GO:0030178]; neural crest cell differentiation [GO:0014033]; positive regulation of apoptotic process [GO:0043065]; positive regulation of fat cell differentiation [GO:0045600]; somite development [GO:0061053] GO:0002064; GO:0005576; GO:0005615; GO:0005737; GO:0008285; GO:0010721; GO:0014033; GO:0017147; GO:0030178; GO:0030308; GO:0042472; GO:0043065; GO:0045600; GO:0060029; GO:0060070; GO:0061037; GO:0061053; GO:0070365; GO:0070367; GO:0090090; GO:0090103 37474 XM_044319794.1 420 149 366 329 564 Q8TEX9 0 Importin-4 (Imp4) (Importin-4b) (Imp4b) (Ran-binding protein 4) (RanBP4) Homo sapiens (Human) protein import into nucleus [GO:0006606]; protein localization to nucleus [GO:0034504] GO:0000785; GO:0005634; GO:0005737; GO:0006606; GO:0008139; GO:0016020; GO:0031267; GO:0032991; GO:0034504; GO:0061608 37475 XM_044308851.1 694 3 1 648 1 NA NA NA NA NA NA 37476 XM_044314130.1 18 19 7 30 186 NA NA NA NA NA NA 37477 XM_044320258.1 0 112 0 0 74 Q08DH3 1.99e-52 Probable tRNA methyltransferase 9B (Probable tRNA methyltransferase 9-like protein) (EC 2.1.1.-) Bos taurus (Bovine) tRNA methylation [GO:0030488]; tRNA wobble uridine modification [GO:0002098] GO:0000049; GO:0002098; GO:0005634; GO:0005737; GO:0030488; GO:0106335 37478 XM_029358185.2 17060 25620 15238 14758 11841 Q3SZ90 9.19e-73 60S ribosomal protein L13a Bos taurus (Bovine) cellular response to type II interferon [GO:0071346]; homeostatic process [GO:0042592]; lung morphogenesis [GO:0060425]; macrophage chemotaxis [GO:0048246]; negative regulation of formation of translation preinitiation complex [GO:1901194]; negative regulation of translation [GO:0017148]; response to lipopolysaccharide [GO:0032496]; translation [GO:0006412] GO:0003729; GO:0003735; GO:0005840; GO:0006412; GO:0017148; GO:0022625; GO:0032496; GO:0042592; GO:0045202; GO:0048246; GO:0060425; GO:0071346; GO:0097452; GO:1901194 37479 XM_029335581.2 1646 1979 1984 2784 2116 Q5BKL0 0 4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) (4-hydroxyphenylpyruvic acid oxidase) (4HPPD) (HPD) (HPPDase) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572] GO:0000139; GO:0003868; GO:0005789; GO:0006559; GO:0006572; GO:0042803; GO:0046872 37480 XM_044307031.1 73 18 34 33 44 NA NA NA NA NA NA 37481 XM_029338257.2 340 1034 0 1011 350 O15014 2.7e-22 Zinc finger protein 609 Homo sapiens (Human) muscle organ development [GO:0007517]; positive regulation of neuron migration [GO:2001224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of myoblast proliferation [GO:2000291]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0005634; GO:0005654; GO:0006357; GO:0007517; GO:0045944; GO:0046872; GO:1990841; GO:2000291; GO:2001224 37482 XM_044329316.1 0 0 0 15 0 NA NA NA NA NA NA 37483 XM_029356774.2 3364 3021 1674 3276 2151 Q3B7L6 8.01e-50 Serine/arginine-rich splicing factor 6 (Splicing factor, arginine/serine-rich 6) Bos taurus (Bovine) alternative mRNA splicing, via spliceosome [GO:0000380]; mRNA splice site selection [GO:0006376]; negative regulation of keratinocyte differentiation [GO:0045617]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of keratinocyte proliferation [GO:0010837]; regulation of wound healing [GO:0061041] GO:0000380; GO:0000381; GO:0003723; GO:0006376; GO:0010837; GO:0016607; GO:0036002; GO:0045617; GO:0048025; GO:0061041 37484 XM_029345211.2 3294 2456 1815 3201 3202 Q08AW4 2.73e-73 Pleckstrin homology domain-containing family M member 3 (PH domain-containing family M member 3) Xenopus laevis (African clawed frog) myoblast differentiation [GO:0045445] GO:0005737; GO:0005794; GO:0005886; GO:0045445; GO:0046872 37485 XM_044309291.1 0 1 0 0 10 NA NA NA NA NA NA 37486 XM_044321943.1 19 0 126 4 117 NA NA NA NA NA NA 37487 XM_044328112.1 153 68 30 63 19 NA NA NA NA NA NA 37488 XM_044325423.1 26 8 33 9 765 NA NA NA NA NA NA 37489 XM_044312005.1 203 13 26 41 27 Q7RTR2 1.47e-61 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 37490 XM_044312005.1 203 13 26 41 27 Q7RTR2 3.71e-50 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 37491 XM_044312005.1 203 13 26 41 27 Q7RTR2 3.13e-38 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 37492 XM_044312005.1 203 13 26 41 27 Q7RTR2 2.09e-35 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 37493 XM_029345794.2 685 2634 503 514 432 Q9D1M0 4.54e-152 Protein SEC13 homolog (GATOR complex protein SEC13) (SEC13-like protein 1) (SEC13-related protein) Mus musculus (Mouse) COPII-coated vesicle budding [GO:0090114]; COPII-coated vesicle cargo loading [GO:0090110]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; mRNA transport [GO:0051028]; nucleocytoplasmic transport [GO:0006913]; positive regulation of TOR signaling [GO:0032008]; protein exit from endoplasmic reticulum [GO:0032527]; protein import into nucleus [GO:0006606]; protein localization to plasma membrane [GO:0072659] GO:0000776; GO:0005198; GO:0005635; GO:0005643; GO:0005654; GO:0005765; GO:0005783; GO:0005789; GO:0005829; GO:0006606; GO:0006888; GO:0006913; GO:0030127; GO:0031080; GO:0032008; GO:0032527; GO:0032991; GO:0042802; GO:0043231; GO:0051028; GO:0061700; GO:0072659; GO:0090110; GO:0090114 37494 XR_006396450.1 0 36 0 0 0 NA NA NA NA NA NA 37495 XM_044321977.1 576 357 353 715 678 P56399 0 Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.4.19.12) (Deubiquitinating enzyme 5) (Isopeptidase T) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) Mus musculus (Mouse) positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004197; GO:0004843; GO:0005634; GO:0005829; GO:0006511; GO:0008270; GO:0016579; GO:0032436; GO:0043130; GO:0071108 37496 XM_044308990.1 151 209 41 163 150 NA NA NA NA NA NA 37497 XM_029348368.2 0 9 0 0 0 NA NA NA NA NA NA 37498 XM_029340495.2 17 214 111 190 96 Q64338 2.78e-118 Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Cam-PDE 1C) (EC 3.1.4.17) Mus musculus (Mouse) negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; response to calcium ion [GO:0051592]; sensory perception of smell [GO:0007608]; signal transduction [GO:0007165] GO:0004114; GO:0004115; GO:0004117; GO:0005516; GO:0005764; GO:0005929; GO:0007165; GO:0007608; GO:0030552; GO:0043025; GO:0046872; GO:0047555; GO:0048101; GO:0051592; GO:0061179 37499 XM_044326302.1 36 38 0 67 9 Q0DXS3 7.51e-134 Probable RNA-dependent RNA polymerase 1 (OsRDR1) (EC 2.7.7.48) Oryza sativa subsp. japonica (Rice) positive regulation of post-transcriptional gene silencing [GO:0060148]; response to salicylic acid [GO:0009751]; response to virus [GO:0009615]; siRNA processing [GO:0030422]; wax biosynthetic process [GO:0010025] GO:0003723; GO:0003968; GO:0009615; GO:0009751; GO:0010025; GO:0030422; GO:0031380; GO:0060148 37500 XM_029326549.2 10 0 3 4 27 NA NA NA NA NA NA 37501 XM_029356406.2 44 49 13 71 46 Q9NRM2 2.24e-116 Zinc finger protein 277 (Nuclear receptor-interacting factor 4) Homo sapiens (Human) cellular response to hydrogen peroxide [GO:0070301]; regulation of cellular senescence [GO:2000772] GO:0000978; GO:0005634; GO:0046872; GO:0070301; GO:2000772 37502 XM_029348937.2 104 36 133 108 274 NA NA NA NA NA NA 37503 XM_044322259.1 0 0 0 7 5 NA NA NA NA NA NA 37504 XM_029328025.2 4 217 2 4 28 NA NA NA NA NA NA 37505 XM_044316579.1 242 187 260 777 446 C3ZQF9 1.07e-31 QRFP-like peptide receptor Branchiostoma floridae (Florida lancelet) (Amphioxus) cellular response to peptide [GO:1901653]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:1901653 37506 XM_029337678.2 439 359 317 489 395 NA NA NA NA NA NA 37507 XM_044312255.1 64 18 28 80 89 NA NA NA NA NA NA 37508 XR_006393903.1 41 2 25 5 151 NA NA NA NA NA NA 37509 XM_029357533.2 4424 4011 2607 3027 2458 NA NA NA NA NA NA 37510 XM_044324364.1 1879 1686 1000 1586 1354 NA NA NA NA NA NA 37511 XM_029352068.2 13 116 5 82 6 NA NA NA NA NA NA 37512 XM_029339590.2 27 61 24 26 39 NA NA NA NA NA NA 37513 XM_044319642.1 77 95 64 25 84 NA NA NA NA NA NA 37514 XR_006393782.1 2 7 2 9 4 NA NA NA NA NA NA 37515 XM_044316513.1 146 52 71 93 176 NA NA NA NA NA NA 37516 XM_044324448.1 0 1 0 9 21 NA NA NA NA NA NA 37517 XM_029326779.2 144 189 130 203 140 NA NA NA NA NA NA 37518 XM_044321425.1 237 45 351 61 0 Q91ZI0 1.29e-64 Cadherin EGF LAG seven-pass G-type receptor 3 Mus musculus (Mouse) axonal fasciculation [GO:0007413]; cell-cell adhesion [GO:0098609]; cilium assembly [GO:0060271]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; planar cell polarity pathway involved in axon guidance [GO:1904938]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] GO:0001932; GO:0004930; GO:0005509; GO:0005886; GO:0007156; GO:0007413; GO:0032880; GO:0036514; GO:0036515; GO:0060271; GO:0097475; GO:0098609; GO:1904938 37519 XM_044321425.1 237 45 351 61 0 Q91ZI0 5.93e-45 Cadherin EGF LAG seven-pass G-type receptor 3 Mus musculus (Mouse) axonal fasciculation [GO:0007413]; cell-cell adhesion [GO:0098609]; cilium assembly [GO:0060271]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; planar cell polarity pathway involved in axon guidance [GO:1904938]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] GO:0001932; GO:0004930; GO:0005509; GO:0005886; GO:0007156; GO:0007413; GO:0032880; GO:0036514; GO:0036515; GO:0060271; GO:0097475; GO:0098609; GO:1904938 37520 XM_044321425.1 237 45 351 61 0 Q91ZI0 1.31e-37 Cadherin EGF LAG seven-pass G-type receptor 3 Mus musculus (Mouse) axonal fasciculation [GO:0007413]; cell-cell adhesion [GO:0098609]; cilium assembly [GO:0060271]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; planar cell polarity pathway involved in axon guidance [GO:1904938]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] GO:0001932; GO:0004930; GO:0005509; GO:0005886; GO:0007156; GO:0007413; GO:0032880; GO:0036514; GO:0036515; GO:0060271; GO:0097475; GO:0098609; GO:1904938 37521 XM_044307591.1 1738 2149 2027 1661 1765 NA NA NA NA NA NA 37522 XM_029349083.2 497 387 205 483 296 Q5FWU8 1.92e-164 Zinc finger MYND domain-containing protein 10 Xenopus laevis (African clawed frog) inner dynein arm assembly [GO:0036159]; motile cilium assembly [GO:0044458]; outer dynein arm assembly [GO:0036158]; positive regulation of motile cilium assembly [GO:1905505] GO:0005929; GO:0016324; GO:0034451; GO:0036158; GO:0036159; GO:0044458; GO:0046872; GO:0120293; GO:1905505 37523 XM_044329031.1 2 4 0 9 15 NA NA NA NA NA NA 37524 XM_029333573.2 36 7 34 56 10 NA NA NA NA NA NA 37525 XR_006396630.1 0 8 49 73 33 NA NA NA NA NA NA 37526 XM_029336729.2 219 165 41 123 13 Q61292 4.22e-117 Laminin subunit beta-2 (Laminin-11 subunit beta) (Laminin-14 subunit beta) (Laminin-15 subunit beta) (Laminin-3 subunit beta) (Laminin-4 subunit beta) (Laminin-7 subunit beta) (Laminin-9 subunit beta) (S-laminin subunit beta) (S-LAM beta) Mus musculus (Mouse) animal organ morphogenesis [GO:0009887]; astrocyte development [GO:0014002]; axon extension involved in regeneration [GO:0048677]; axon guidance [GO:0007411]; basement membrane assembly [GO:0070831]; cell migration [GO:0016477]; cell morphogenesis involved in differentiation [GO:0000904]; metanephric glomerular basement membrane development [GO:0072274]; metanephric podocyte development [GO:0072249]; neuromuscular junction development [GO:0007528]; neuron projection development [GO:0031175]; positive regulation of cell adhesion [GO:0045785]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of muscle cell differentiation [GO:0051149]; regulation of basement membrane organization [GO:0110011]; retina development in camera-type eye [GO:0060041]; Schwann cell development [GO:0014044]; substrate adhesion-dependent cell spreading [GO:0034446]; synapse organization [GO:0050808]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0000904; GO:0005178; GO:0005201; GO:0005576; GO:0005604; GO:0005608; GO:0007411; GO:0007528; GO:0007601; GO:0009887; GO:0009888; GO:0014002; GO:0014044; GO:0016477; GO:0031175; GO:0031594; GO:0034446; GO:0043083; GO:0043256; GO:0045202; GO:0045785; GO:0048677; GO:0050808; GO:0051149; GO:0060041; GO:0062023; GO:0070831; GO:0072249; GO:0072274; GO:0098637; GO:0110011; GO:0150043; GO:2001046 37527 XM_044321898.1 542 572 340 778 852 E9PYK3 0 Protein mono-ADP-ribosyltransferase PARP4 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 4) (ARTD4) (Poly [ADP-ribose] polymerase 4) (PARP-4) (Vault poly(ADP-ribose) polymerase) (VPARP) (mVparp) Mus musculus (Mouse) cell death [GO:0008219]; inflammatory response [GO:0006954]; protein modification process [GO:0036211]; regulation of telomerase activity [GO:0051972] GO:0003950; GO:0005634; GO:0005654; GO:0005737; GO:0005819; GO:0005829; GO:0005876; GO:0006954; GO:0008219; GO:0016779; GO:0019899; GO:0036211; GO:0051972; GO:1990404; GO:1990904 37528 XM_044323386.1 55 0 0 17 45 NA NA NA NA NA NA 37529 XR_006396359.1 274 302 144 270 284 NA NA NA NA NA NA 37530 XR_006393009.1 41 2 25 5 151 NA NA NA NA NA NA 37531 XM_044313726.1 0 0 16 0 82 Q96RW7 4.2e-29 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 37532 XM_044313726.1 0 0 16 0 82 Q96RW7 3.28e-25 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 37533 XM_044313726.1 0 0 16 0 82 Q96RW7 1.03e-23 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 37534 XM_044313726.1 0 0 16 0 82 Q96RW7 2.16e-23 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 37535 XM_044313726.1 0 0 16 0 82 Q96RW7 3e-23 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 37536 XM_044313726.1 0 0 16 0 82 Q96RW7 1.26e-22 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 37537 XM_044313726.1 0 0 16 0 82 Q96RW7 8.06e-21 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 37538 XM_044313726.1 0 0 16 0 82 Q96RW7 8.21e-21 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 37539 XM_044327122.1 25 76 56 47 64 NA NA NA NA NA NA 37540 XM_044309179.1 428 246 305 1060 1517 A6QLU1 0 Glycerol-3-phosphate dehydrogenase, mitochondrial (GPD-M) (GPDH-M) (EC 1.1.5.3) Bos taurus (Bovine) glycerol catabolic process [GO:0019563]; glycerol-3-phosphate metabolic process [GO:0006072] GO:0004368; GO:0005509; GO:0005739; GO:0006072; GO:0009331; GO:0019563; GO:0052591 37541 XM_029338203.2 823 1010 695 875 867 Q28GE1 6.81e-63 Mediator of RNA polymerase II transcription subunit 18 (Mediator complex subunit 18) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) regulation of transcription by RNA polymerase II [GO:0006357] GO:0003712; GO:0006357; GO:0016592 37542 XM_029347949.2 3807 2970 2690 3722 2968 P16591 1.82e-176 Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) (Fujinami poultry sarcoma/Feline sarcoma-related protein Fer) (Proto-oncogene c-Fer) (Tyrosine kinase 3) (p94-Fer) Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; adherens junction assembly [GO:0034333]; adherens junction disassembly [GO:0120179]; cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; cell-cell adhesion mediated by cadherin [GO:0044331]; cellular response to insulin stimulus [GO:0032869]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to reactive oxygen species [GO:0034614]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; diapedesis [GO:0050904]; extracellular matrix-cell signaling [GO:0035426]; Fc-epsilon receptor signaling pathway [GO:0038095]; germ cell development [GO:0007281]; innate immune response [GO:0045087]; insulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028]; interleukin-6-mediated signaling pathway [GO:0070102]; intracellular signal transduction [GO:0035556]; Kit signaling pathway [GO:0038109]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of mast cell activation involved in immune response [GO:0033007]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of fibroblast migration [GO:0010762]; regulation of lamellipodium assembly [GO:0010591]; regulation of mast cell degranulation [GO:0043304]; regulation of protein phosphorylation [GO:0001932]; response to lipopolysaccharide [GO:0032496]; response to platelet-derived growth factor [GO:0036119]; Sertoli cell development [GO:0060009]; substrate adhesion-dependent cell spreading [GO:0034446]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; tyrosine phosphorylation of STAT protein [GO:0007260] GO:0000226; GO:0001932; GO:0003779; GO:0004713; GO:0004715; GO:0005102; GO:0005154; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0005938; GO:0006468; GO:0006935; GO:0007155; GO:0007169; GO:0007260; GO:0007281; GO:0008157; GO:0008284; GO:0008289; GO:0010591; GO:0010762; GO:0018108; GO:0019221; GO:0030154; GO:0030335; GO:0030838; GO:0031234; GO:0031267; GO:0031532; GO:0032496; GO:0032869; GO:0033007; GO:0034333; GO:0034446; GO:0034614; GO:0035426; GO:0035556; GO:0036006; GO:0036119; GO:0038028; GO:0038095; GO:0038109; GO:0042058; GO:0042995; GO:0043304; GO:0044331; GO:0045087; GO:0045098; GO:0045295; GO:0045296; GO:0046777; GO:0048008; GO:0050904; GO:0051092; GO:0060009; GO:0070097; GO:0070102; GO:0070161; GO:0120179; GO:1990782 37543 XM_044322937.1 18 6 0 9 19 NA NA NA NA NA NA 37544 XM_044325482.1 15 30 17 58 79 Q9Z0J5 3.67e-121 Thioredoxin reductase 2, mitochondrial (EC 1.8.1.9) (Thioredoxin reductase TR3) Rattus norvegicus (Rat) cell redox homeostasis [GO:0045454]; heart development [GO:0007507]; hemopoiesis [GO:0030097]; protein-containing complex assembly [GO:0065003]; response to hydrogen peroxide [GO:0042542]; response to hyperoxia [GO:0055093]; response to oxygen radical [GO:0000305]; response to selenium ion [GO:0010269]; response to xenobiotic stimulus [GO:0009410] GO:0000305; GO:0004791; GO:0005737; GO:0005739; GO:0005829; GO:0007507; GO:0009410; GO:0010269; GO:0030097; GO:0030424; GO:0030425; GO:0042542; GO:0042803; GO:0043025; GO:0044877; GO:0045454; GO:0050660; GO:0055093; GO:0065003 37545 XM_044321981.1 2902 2679 1374 1926 1016 Q9H0C1 6.42e-114 Zinc finger MYND domain-containing protein 12 Homo sapiens (Human) NA GO:0046872 37546 XM_044319202.1 119 87 108 106 33 P0DX22 3.53e-52 NA NA NA NA 37547 XR_006393321.1 0 24 0 21 4 NA NA NA NA NA NA 37548 XR_006395529.1 434 0 13 0 0 P53992 0 Protein transport protein Sec24C (SEC24-related protein C) Homo sapiens (Human) COPII-coated vesicle cargo loading [GO:0090110]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; in utero embryonic development [GO:0001701]; intracellular protein transport [GO:0006886] GO:0000149; GO:0001701; GO:0005789; GO:0005829; GO:0006886; GO:0006888; GO:0008270; GO:0012507; GO:0030127; GO:0070971; GO:0090110 37549 XM_044324233.1 32 5444 7582 0 9102 NA NA NA NA NA NA 37550 XR_003826950.2 17 3 12 13 30 NA NA NA NA NA NA 37551 XM_029335727.2 126 864 341 691 330 NA NA NA NA NA NA 37552 XM_044311195.1 59 439 531 456 920 Q5TJ56 4.64e-44 Formin-F (Diaphanous-related formin dia1) Dictyostelium discoideum (Social amoeba) 'de novo' actin filament nucleation [GO:0070060]; actin filament polymerization [GO:0030041]; positive phototaxis [GO:0046956] GO:0005522; GO:0015629; GO:0030041; GO:0031143; GO:0031267; GO:0046956; GO:0051015; GO:0070060 37553 XM_029329078.2 3027 2669 1688 2984 2983 P41778 1.96e-159 Pre-B-cell leukemia transcription factor 1 (Homeobox protein PBX1) Mus musculus (Mouse) adrenal gland development [GO:0030325]; animal organ morphogenesis [GO:0009887]; anterior/posterior pattern specification [GO:0009952]; brain development [GO:0007420]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell population proliferation [GO:0008283]; embryonic hemopoiesis [GO:0035162]; embryonic limb morphogenesis [GO:0030326]; embryonic organ development [GO:0048568]; embryonic skeletal system development [GO:0048706]; eye development [GO:0001654]; G2/M transition of mitotic cell cycle [GO:0000086]; natural killer cell differentiation [GO:0001779]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of neuron differentiation [GO:0045665]; neuron development [GO:0048666]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proximal/distal pattern formation [GO:0009954]; regulation of cell population proliferation [GO:0042127]; regulation of ossification [GO:0030278]; regulation of transcription by RNA polymerase II [GO:0006357]; sex differentiation [GO:0007548]; spleen development [GO:0048536]; stem cell proliferation [GO:0072089]; steroid biosynthetic process [GO:0006694]; thymus development [GO:0048538]; urogenital system development [GO:0001655] GO:0000086; GO:0000976; GO:0000977; GO:0000978; GO:0000981; GO:0001221; GO:0001222; GO:0001228; GO:0001654; GO:0001655; GO:0001658; GO:0001779; GO:0003677; GO:0005634; GO:0005654; GO:0005667; GO:0005737; GO:0006357; GO:0006694; GO:0007420; GO:0007548; GO:0008283; GO:0009887; GO:0009952; GO:0009954; GO:0010971; GO:0030278; GO:0030325; GO:0030326; GO:0035162; GO:0042127; GO:0043433; GO:0043565; GO:0045665; GO:0045944; GO:0048536; GO:0048538; GO:0048568; GO:0048666; GO:0048706; GO:0072089; GO:0090575; GO:0140297; GO:1990837; GO:2000648 37554 XM_029339885.2 1059 934 603 633 738 Q9Y2Y1 2.58e-42 DNA-directed RNA polymerase III subunit RPC10 (RNA polymerase III subunit C10) (DNA-directed RNA polymerase III subunit K) (RNA polymerase III 12.5 kDa subunit) (RPC12.5) (RNA polymerase III subunit C11) (HsC11p) (RPC11) (hRPC11) Homo sapiens (Human) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; termination of RNA polymerase III transcription [GO:0006386]; transcription by RNA polymerase III [GO:0006383]; tRNA 3'-trailer cleavage [GO:0042779] GO:0003676; GO:0003899; GO:0005654; GO:0005666; GO:0005730; GO:0005829; GO:0006383; GO:0006386; GO:0008270; GO:0042779; GO:0045087; GO:0051607 37555 XM_044309705.1 8 0 11 1 16 NA NA NA NA NA NA 37556 XM_029337244.2 1634 1171 910 1573 1363 Q8K394 6.74e-73 Inactive phospholipase C-like protein 2 (PLC-L(2)) (PLC-L2) (Phospholipase C-L2) (Phospholipase C-epsilon-2) (PLC-epsilon-2) Mus musculus (Mouse) B cell proliferation involved in immune response [GO:0002322]; B-1a B cell differentiation [GO:0002337]; gamma-aminobutyric acid signaling pathway [GO:0007214]; lipid metabolic process [GO:0006629]; negative regulation of B cell receptor signaling pathway [GO:0050859]; negative regulation of cold-induced thermogenesis [GO:0120163]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of receptor binding [GO:1900122]; regulation of synaptic transmission, GABAergic [GO:0032228] GO:0002322; GO:0002337; GO:0004435; GO:0005737; GO:0006629; GO:0007214; GO:0032228; GO:0048015; GO:0050811; GO:0050859; GO:0070679; GO:0120163; GO:1900122 37557 XR_006391315.1 109 17 67 89 114 Q8NBN7 9.3e-55 Retinol dehydrogenase 13 (EC 1.1.1.300) (Short chain dehydrogenase/reductase family 7C member 3) Homo sapiens (Human) eye photoreceptor cell development [GO:0042462]; response to high light intensity [GO:0009644]; retina layer formation [GO:0010842]; retinal metabolic process [GO:0042574] GO:0005743; GO:0009644; GO:0010842; GO:0042462; GO:0042574; GO:0052650 37558 XR_006391315.1 109 17 67 89 114 Q8NBN7 9.3e-55 Retinol dehydrogenase 13 (EC 1.1.1.300) (Short chain dehydrogenase/reductase family 7C member 3) Homo sapiens (Human) eye photoreceptor cell development [GO:0042462]; response to high light intensity [GO:0009644]; retina layer formation [GO:0010842]; retinal metabolic process [GO:0042574] GO:0005743; GO:0009644; GO:0010842; GO:0042462; GO:0042574; GO:0052650 37559 XM_029356915.2 9 4 11 0 0 NA NA NA NA NA NA 37560 XR_003825515.2 34 22 0 0 0 NA NA NA NA NA NA 37561 XM_044312943.1 404 579 423 411 518 P43249 0 G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK5) Bos taurus (Bovine) apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell population proliferation [GO:0008284]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell cycle [GO:0051726]; regulation of signal transduction [GO:0009966]; tachykinin receptor signaling pathway [GO:0007217]; Wnt signaling pathway [GO:0016055] GO:0004672; GO:0004674; GO:0004703; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006468; GO:0006915; GO:0007217; GO:0008284; GO:0008289; GO:0009966; GO:0016055; GO:0016607; GO:0031965; GO:0043066; GO:0046777; GO:0047696; GO:0051726 37562 XM_029355437.2 2434 1527 1363 1804 2098 Q9P2G1 0 Ankyrin repeat and IBR domain-containing protein 1 (EC 2.3.2.31) Homo sapiens (Human) positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000151; GO:0000209; GO:0005737; GO:0006511; GO:0031624; GO:0032436; GO:0046872; GO:0061630 37563 XM_029352607.2 55 62 149 0 205 Q5YLH5 3.31e-28 Homeobox protein Hox-A6 Gallus gallus (Chicken) anterior/posterior pattern specification [GO:0009952]; embryonic skeletal system development [GO:0048706]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0009952; GO:0016607; GO:0048706 37564 XM_029328861.2 91 43 78 99 160 O75311 6.07e-64 Glycine receptor subunit alpha-3 Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; neuropeptide signaling pathway [GO:0007218]; protein homooligomerization [GO:0051260]; regulation of membrane potential [GO:0042391]; response to amino acid [GO:0043200]; signal transduction [GO:0007165]; synaptic transmission, glycinergic [GO:0060012] GO:0004888; GO:0005231; GO:0005886; GO:0007165; GO:0007218; GO:0007268; GO:0016594; GO:0016934; GO:0016935; GO:0022852; GO:0030425; GO:0030594; GO:0034220; GO:0042391; GO:0043005; GO:0043200; GO:0043204; GO:0045202; GO:0045211; GO:0046872; GO:0050877; GO:0051260; GO:0060012; GO:1902476; GO:1904315 37565 XM_029337952.2 72 352 376 167 245 P42674 5.49e-33 Blastula protease 10 (EC 3.4.24.-) Paracentrotus lividus (Common sea urchin) proteolysis [GO:0006508] GO:0004222; GO:0005615; GO:0005938; GO:0006508; GO:0008270; GO:0048471 37566 XM_029358329.2 1879 1124 1230 1628 1979 O57429 2.14e-119 Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.4.19.12) (41 kDa ubiquitin-specific protease) (Deubiquitinating enzyme 2) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) Gallus gallus (Chicken) protein deubiquitination [GO:0016579]; rhythmic process [GO:0048511]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004843; GO:0005737; GO:0006511; GO:0016579; GO:0046872; GO:0048471; GO:0048511 37567 XM_044309691.1 29 20 46 20 67 NA NA NA NA NA NA 37568 XR_006392392.1 186 69 73 24 226 NA NA NA NA NA NA 37569 XM_044319871.1 5 0 7 6 14 NA NA NA NA NA NA 37570 XM_044322589.1 13 12 6 13 42 NA NA NA NA NA NA 37571 XM_044313195.1 2 2 0 45 0 NA NA NA NA NA NA 37572 XM_029358260.2 4 0 33 0 0 NA NA NA NA NA NA 37573 XM_029343274.2 261 166 239 130 282 NA NA NA NA NA NA 37574 XM_044308663.1 8 29 28 21 38 D3YXG0 3.7e-66 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 37575 XM_044308663.1 8 29 28 21 38 D3YXG0 1.94e-51 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 37576 XM_044308663.1 8 29 28 21 38 D3YXG0 2.65e-47 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 37577 XM_044308663.1 8 29 28 21 38 D3YXG0 1.59e-40 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 37578 XM_044308663.1 8 29 28 21 38 D3YXG0 1.59e-40 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 37579 XM_044308663.1 8 29 28 21 38 D3YXG0 1.9e-40 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 37580 XM_044308663.1 8 29 28 21 38 D3YXG0 3.28e-40 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 37581 XM_044308663.1 8 29 28 21 38 D3YXG0 2.53e-39 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 37582 XM_044308663.1 8 29 28 21 38 D3YXG0 4.92e-39 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 37583 XM_044308663.1 8 29 28 21 38 D3YXG0 9.65e-38 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 37584 XM_044308663.1 8 29 28 21 38 D3YXG0 1.12e-36 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 37585 XM_044308663.1 8 29 28 21 38 D3YXG0 1.57e-36 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 37586 XR_006393214.1 26 35 3 16 45 Q9BPW9 4.66e-57 Dehydrogenase/reductase SDR family member 9 (EC 1.1.1.209) (EC 1.1.1.53) (3-alpha hydroxysteroid dehydrogenase) (3-alpha-HSD) (NADP-dependent retinol dehydrogenase/reductase) (RDH-E2) (RDHL) (Retinol dehydrogenase 15) (EC 1.1.1.105) (Short chain dehydrogenase/reductase family 9C member 4) (Short-chain dehydrogenase/reductase retSDR8) (Tracheobronchial epithelial cell-specific retinol dehydrogenase) (RDH-TBE) Homo sapiens (Human) 9-cis-retinoic acid biosynthetic process [GO:0042904]; androgen metabolic process [GO:0008209]; epithelial cell differentiation [GO:0030855]; progesterone metabolic process [GO:0042448]; retinol metabolic process [GO:0042572]; steroid metabolic process [GO:0008202] GO:0004022; GO:0004745; GO:0005789; GO:0008202; GO:0008209; GO:0016491; GO:0016854; GO:0030855; GO:0042448; GO:0042572; GO:0042904; GO:0043231; GO:0047023; GO:0047035; GO:0047044 37587 XR_006393214.1 26 35 3 16 45 Q9BPW9 4.66e-57 Dehydrogenase/reductase SDR family member 9 (EC 1.1.1.209) (EC 1.1.1.53) (3-alpha hydroxysteroid dehydrogenase) (3-alpha-HSD) (NADP-dependent retinol dehydrogenase/reductase) (RDH-E2) (RDHL) (Retinol dehydrogenase 15) (EC 1.1.1.105) (Short chain dehydrogenase/reductase family 9C member 4) (Short-chain dehydrogenase/reductase retSDR8) (Tracheobronchial epithelial cell-specific retinol dehydrogenase) (RDH-TBE) Homo sapiens (Human) 9-cis-retinoic acid biosynthetic process [GO:0042904]; androgen metabolic process [GO:0008209]; epithelial cell differentiation [GO:0030855]; progesterone metabolic process [GO:0042448]; retinol metabolic process [GO:0042572]; steroid metabolic process [GO:0008202] GO:0004022; GO:0004745; GO:0005789; GO:0008202; GO:0008209; GO:0016491; GO:0016854; GO:0030855; GO:0042448; GO:0042572; GO:0042904; GO:0043231; GO:0047023; GO:0047035; GO:0047044 37588 XM_044308220.1 496 508 233 422 419 Q6GPB9 0 Dynein axonemal intermediate chain 4 (WD repeat-containing protein 78) Xenopus laevis (African clawed frog) NA GO:0005856; GO:0031514; GO:0120293 37589 XM_044317079.1 64 117 12 109 15 O95935 2.77e-95 T-box transcription factor TBX18 (T-box protein 18) Homo sapiens (Human) cell fate specification [GO:0001708]; cochlea morphogenesis [GO:0090103]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation [GO:0060829]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of SA node cell action potential [GO:0098907]; regulation of transcription by RNA polymerase II [GO:0006357]; sinoatrial node cell development [GO:0060931]; sinoatrial node cell fate commitment [GO:0060930]; sinoatrial node development [GO:0003163]; smooth muscle cell differentiation [GO:0051145]; somitogenesis [GO:0001756]; ureter development [GO:0072189] GO:0000785; GO:0000976; GO:0000978; GO:0000981; GO:0001227; GO:0001708; GO:0001756; GO:0003163; GO:0005634; GO:0005654; GO:0006357; GO:0016331; GO:0042803; GO:0045893; GO:0051145; GO:0060829; GO:0060930; GO:0060931; GO:0072189; GO:0090103; GO:0090571; GO:0098907; GO:1990837 37590 XM_029339729.2 5445 4411 1961 3267 4865 G1TFM5 1.36e-132 NA NA NA NA 37591 XM_029339861.2 53 28 25 37 28 Q9H5Z1 0 Probable ATP-dependent RNA helicase DHX35 (EC 3.6.4.13) (DEAH box protein 35) Homo sapiens (Human) in utero embryonic development [GO:0001701]; mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0001701; GO:0003723; GO:0003724; GO:0005524; GO:0016887; GO:0071013 37592 XM_044311354.1 0 0 6 0 0 Q95LR0 5.32e-32 Cilia- and flagella-associated protein 91 (CFAP91) (AMY-1-associating protein expressed in testis 1) (AAT-1) (MYCBP/AMY-1-associated testis-expressed protein 1) (Protein MAATS1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) axonemal central apparatus assembly [GO:1904158]; cell differentiation [GO:0030154]; cilium movement [GO:0003341]; spermatogenesis [GO:0007283] GO:0003341; GO:0005739; GO:0005930; GO:0007283; GO:0030154; GO:0031514; GO:1904158 37593 XM_044311354.1 0 0 6 0 0 Q95LR0 5.32e-32 Cilia- and flagella-associated protein 91 (CFAP91) (AMY-1-associating protein expressed in testis 1) (AAT-1) (MYCBP/AMY-1-associated testis-expressed protein 1) (Protein MAATS1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) axonemal central apparatus assembly [GO:1904158]; cell differentiation [GO:0030154]; cilium movement [GO:0003341]; spermatogenesis [GO:0007283] GO:0003341; GO:0005739; GO:0005930; GO:0007283; GO:0030154; GO:0031514; GO:1904158 37594 XM_029346516.2 0 9 82 0 0 Q9PTS8 1.41e-93 Neuronal acetylcholine receptor subunit alpha-9 (Nicotinic acetylcholine receptor subunit alpha-9) (NACHR alpha-9) Gallus gallus (Chicken) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; regulation of nitric oxide metabolic process [GO:0080164]; response to auditory stimulus [GO:0010996]; signal transduction [GO:0007165] GO:0004888; GO:0005231; GO:0005262; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0010996; GO:0022848; GO:0030594; GO:0034220; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051899; GO:0080164; GO:1904315 37595 XM_044313809.1 85 82 46 17 66 NA NA NA NA NA NA 37596 XM_044311936.1 0 0 4 13 4 NA NA NA NA NA NA 37597 XM_029351555.2 216 140 120 166 212 P46718 2.58e-96 Programmed cell death protein 2 (Zinc finger protein Rp-8) Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; regulation of hematopoietic progenitor cell differentiation [GO:1901532] GO:0003677; GO:0005634; GO:0005737; GO:0006915; GO:0006919; GO:0019899; GO:0043065; GO:0046872; GO:1901532; GO:1902035 37598 XM_044320441.1 0 0 312 149 160 NA NA NA NA NA NA 37599 XM_029336507.2 5 358 142 309 123 NA NA NA NA NA NA 37600 XM_029340547.2 48 47 44 57 87 Q5EAB6 0 Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGnT1) (EC 2.4.1.-) Bos taurus (Bovine) O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493] GO:0000139; GO:0006493; GO:0008375; GO:0016020; GO:0016266; GO:0030145 37601 XM_044313571.1 13 20 0 2 4 NA NA NA NA NA NA 37602 XR_003824591.2 35 42 35 82 88 NA NA NA NA NA NA 37603 XR_006395980.1 314 237 382 270 357 Q54NA6 1.35e-54 Myb-like protein L Dictyostelium discoideum (Social amoeba) regulation of DNA-templated transcription [GO:0006355] GO:0000978; GO:0000981; GO:0005634; GO:0006355 37604 XM_044321673.1 69 54 221 77 206 P35439 5.25e-53 Glutamate receptor ionotropic, NMDA 1 (GluN1) (Glutamate [NMDA] receptor subunit zeta-1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1) Rattus norvegicus (Rat) adult locomotory behavior [GO:0008344]; associative learning [GO:0008306]; calcium ion homeostasis [GO:0055074]; calcium ion transmembrane import into cytosol [GO:0097553]; calcium ion transport [GO:0006816]; cation transmembrane transport [GO:0098655]; cation transport [GO:0006812]; cellular calcium ion homeostasis [GO:0006874]; cellular response to manganese ion [GO:0071287]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; conditioned taste aversion [GO:0001661]; excitatory postsynaptic potential [GO:0060079]; ionotropic glutamate receptor signaling pathway [GO:0035235]; learning [GO:0007612]; learning or memory [GO:0007611]; long-term memory [GO:0007616]; male mating behavior [GO:0060179]; memory [GO:0007613]; negative regulation of neuron apoptotic process [GO:0043524]; neuromuscular process [GO:0050905]; neuron cellular homeostasis [GO:0070050]; olfactory learning [GO:0008355]; pons maturation [GO:0021586]; positive regulation of apoptotic process [GO:0043065]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of cell death [GO:0010942]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of dendritic spine maintenance [GO:1902952]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of Schwann cell migration [GO:1900149]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; prepulse inhibition [GO:0060134]; propylene metabolic process [GO:0018964]; protein heterotetramerization [GO:0051290]; protein localization to postsynaptic membrane [GO:1903539]; protein-containing complex assembly [GO:0065003]; regulation of axonogenesis [GO:0050770]; regulation of cation transmembrane transport [GO:1904062]; regulation of cell communication [GO:0010646]; regulation of dendrite morphogenesis [GO:0048814]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of membrane potential [GO:0042391]; regulation of neuron apoptotic process [GO:0043523]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of respiratory gaseous exchange [GO:0043576]; regulation of synapse assembly [GO:0051963]; regulation of synaptic plasticity [GO:0048167]; response to amine [GO:0014075]; response to amphetamine [GO:0001975]; response to calcium ion [GO:0051592]; response to ethanol [GO:0045471]; response to fungicide [GO:0060992]; response to glycine [GO:1905429]; response to morphine [GO:0043278]; response to organic cyclic compound [GO:0014070]; rhythmic process [GO:0048511]; sensory perception of pain [GO:0019233]; social behavior [GO:0035176]; startle response [GO:0001964]; suckling behavior [GO:0001967]; synaptic transmission, glutamatergic [GO:0035249]; transcription by RNA polymerase II [GO:0006366]; visual learning [GO:0008542] GO:0001540; GO:0001661; GO:0001964; GO:0001967; GO:0001975; GO:0004970; GO:0004972; GO:0005102; GO:0005261; GO:0005262; GO:0005509; GO:0005516; GO:0005737; GO:0005783; GO:0005789; GO:0005886; GO:0006366; GO:0006812; GO:0006816; GO:0006874; GO:0007268; GO:0007611; GO:0007612; GO:0007613; GO:0007616; GO:0008021; GO:0008306; GO:0008344; GO:0008355; GO:0008542; GO:0009986; GO:0010524; GO:0010646; GO:0010942; GO:0014069; GO:0014070; GO:0014075; GO:0015276; GO:0016020; GO:0016594; GO:0016595; GO:0017146; GO:0018964; GO:0019233; GO:0019899; GO:0019902; GO:0021586; GO:0021987; GO:0022843; GO:0022849; GO:0030425; GO:0030672; GO:0032590; GO:0035176; GO:0035235; GO:0035249; GO:0035254; GO:0038023; GO:0042165; GO:0042391; GO:0042734; GO:0043005; GO:0043025; GO:0043065; GO:0043083; GO:0043195; GO:0043197; GO:0043278; GO:0043523; GO:0043524; GO:0043576; GO:0044307; GO:0044877; GO:0045202; GO:0045211; GO:0045471; GO:0045944; GO:0048167; GO:0048168; GO:0048169; GO:0048511; GO:0048787; GO:0048814; GO:0050770; GO:0050905; GO:0051290; GO:0051592; GO:0051963; GO:0051968; GO:0055074; GO:0060076; GO:0060079; GO:0060134; GO:0060179; GO:0060992; GO:0065003; GO:0070050; GO:0071287; GO:0097060; GO:0097553; GO:0098655; GO:0098686; GO:0098688; GO:0098839; GO:0098978; GO:0099507; GO:1900149; GO:1902952; GO:1903428; GO:1903539; GO:1904062; GO:1904315; GO:1905429; GO:2000463; GO:2001056 37605 XM_044325279.1 39 29 49 69 53 NA NA NA NA NA NA 37606 XR_006391929.1 76 0 12 171 20 NA NA NA NA NA NA 37607 XM_044328138.1 0 0 18 30 0 NA NA NA NA NA NA 37608 XM_029350056.2 660 607 278 115 317 NA NA NA NA NA NA 37609 XM_044327790.1 162 194 178 315 688 NA NA NA NA NA NA 37610 XM_029325724.2 838 813 464 886 330 O22943 5.17e-89 Probable glycosyltransferase STELLO1 (EC 2.4.-.-) Arabidopsis thaliana (Mouse-ear cress) plant-type cell wall cellulose biosynthetic process [GO:0052324]; regulation of plant-type cell wall cellulose biosynthetic process [GO:2001009] GO:0000139; GO:0005768; GO:0005794; GO:0005802; GO:0016757; GO:0042802; GO:0052324; GO:2001009 37611 XM_029358398.2 1144 1062 527 989 918 P54100 3.23e-172 Proto-oncogene vav (p95) Rattus norvegicus (Rat) cell development [GO:0048468]; cell migration [GO:0016477]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; immune response-regulating cell surface receptor signaling pathway [GO:0002768]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; neutrophil chemotaxis [GO:0030593]; phagocytosis [GO:0006909]; positive regulation of cell adhesion [GO:0045785]; positive regulation of GTPase activity [GO:0043547]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; reactive oxygen species metabolic process [GO:0072593]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217] GO:0001784; GO:0002768; GO:0005085; GO:0005737; GO:0005911; GO:0006909; GO:0006955; GO:0007186; GO:0007229; GO:0008361; GO:0016477; GO:0030217; GO:0030593; GO:0035556; GO:0042110; GO:0043087; GO:0043547; GO:0045785; GO:0045954; GO:0046872; GO:0048468; GO:0072593; GO:0140031 37612 XM_044307999.1 0 0 0 0 36 NA NA NA NA NA NA 37613 XM_029357309.2 458 406 182 451 302 Q8K4C0 0 Flavin-containing monooxygenase 5 (FMO 5) (Dimethylaniline monooxygenase [N-oxide-forming] 5) (EC 1.14.13.8) (Dimethylaniline oxidase 5) (Hepatic flavin-containing monooxygenase 5) (NADPH oxidase) (EC 1.6.3.1) Rattus norvegicus (Rat) lipid metabolic process [GO:0006629]; NADPH oxidation [GO:0070995]; regulation of cholesterol metabolic process [GO:0090181]; xenobiotic metabolic process [GO:0006805] GO:0004031; GO:0004497; GO:0004499; GO:0005789; GO:0006629; GO:0006805; GO:0047822; GO:0050660; GO:0050661; GO:0070995; GO:0090181; GO:0106294 37614 XM_029330524.2 0 0 0 0 267 NA NA NA NA NA NA 37615 XM_029331587.2 0 15 0 58 0 NA NA NA NA NA NA 37616 XM_044327522.1 129 0 21 0 63 Q5XIN7 3.82e-172 Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGnT1) (EC 2.4.1.-) Rattus norvegicus (Rat) O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493] GO:0000139; GO:0006493; GO:0008375; GO:0016020; GO:0016266; GO:0030145; GO:0047223 37617 XM_044309534.1 175 18 132 26 334 Q9UGM3 9.02e-58 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 37618 XM_044309534.1 175 18 132 26 334 Q9UGM3 6.57e-56 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 37619 XM_044309534.1 175 18 132 26 334 Q9UGM3 2.71e-55 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 37620 XM_044309534.1 175 18 132 26 334 Q9UGM3 1.84e-54 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 37621 XM_044309534.1 175 18 132 26 334 Q9UGM3 2.33e-54 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 37622 XM_044309534.1 175 18 132 26 334 Q9UGM3 3.09e-54 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 37623 XM_044309534.1 175 18 132 26 334 Q9UGM3 3.51e-54 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 37624 XM_044309534.1 175 18 132 26 334 Q9UGM3 3.77e-54 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 37625 XM_044309534.1 175 18 132 26 334 Q9UGM3 4.56e-54 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 37626 XM_044309534.1 175 18 132 26 334 Q9UGM3 4.99e-54 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 37627 XM_044309534.1 175 18 132 26 334 Q9UGM3 9e-54 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 37628 XM_044309534.1 175 18 132 26 334 Q9UGM3 1.43e-34 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 37629 XM_029348125.2 61 0 49 283 75 NA NA NA NA NA NA 37630 XM_044314928.1 15 0 15 21 34 Q2TBP0 1.93e-44 Proteasome subunit beta type-7 (EC 3.4.25.1) Bos taurus (Bovine) proteolysis involved in protein catabolic process [GO:0051603] GO:0004298; GO:0005634; GO:0005737; GO:0005839; GO:0019774; GO:0051603 37631 XM_044314928.1 15 0 15 21 34 Q2TBP0 1.93e-44 Proteasome subunit beta type-7 (EC 3.4.25.1) Bos taurus (Bovine) proteolysis involved in protein catabolic process [GO:0051603] GO:0004298; GO:0005634; GO:0005737; GO:0005839; GO:0019774; GO:0051603 37632 XM_044314928.1 15 0 15 21 34 Q2TBP0 1.93e-44 Proteasome subunit beta type-7 (EC 3.4.25.1) Bos taurus (Bovine) proteolysis involved in protein catabolic process [GO:0051603] GO:0004298; GO:0005634; GO:0005737; GO:0005839; GO:0019774; GO:0051603 37633 XM_029338636.2 479 169 216 205 204 Q6DCV0 9.86e-137 WD repeat domain phosphoinositide-interacting protein 4 (WIPI-4) (WD repeat-containing protein 45) Xenopus laevis (African clawed frog) autophagosome assembly [GO:0000045]; cellular response to starvation [GO:0009267]; positive regulation of autophagosome assembly [GO:2000786] GO:0000045; GO:0000407; GO:0009267; GO:0032266; GO:1901981; GO:2000786 37634 XM_029349597.2 2365 1101 458 1557 900 NA NA NA NA NA NA 37635 XM_029328231.2 521 636 161 628 403 Q5UNS8 1.67e-31 Uncharacterized protein R665 Acanthamoeba polyphaga mimivirus (APMV) NA NA 37636 XM_029342699.2 499 236 281 407 575 NA NA NA NA NA NA 37637 XM_044309225.1 147 42 46 215 158 Q6V4S5 6.87e-52 Protein sidekick-2 Mus musculus (Mouse) camera-type eye photoreceptor cell differentiation [GO:0060219]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; retina layer formation [GO:0010842]; synapse assembly [GO:0007416] GO:0005886; GO:0007156; GO:0007416; GO:0010842; GO:0045202; GO:0060219 37638 XM_044309225.1 147 42 46 215 158 Q6V4S5 7.47e-47 Protein sidekick-2 Mus musculus (Mouse) camera-type eye photoreceptor cell differentiation [GO:0060219]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; retina layer formation [GO:0010842]; synapse assembly [GO:0007416] GO:0005886; GO:0007156; GO:0007416; GO:0010842; GO:0045202; GO:0060219 37639 XM_044309225.1 147 42 46 215 158 Q6V4S5 3.91e-40 Protein sidekick-2 Mus musculus (Mouse) camera-type eye photoreceptor cell differentiation [GO:0060219]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; retina layer formation [GO:0010842]; synapse assembly [GO:0007416] GO:0005886; GO:0007156; GO:0007416; GO:0010842; GO:0045202; GO:0060219 37640 XM_044309225.1 147 42 46 215 158 Q6V4S5 5.13e-33 Protein sidekick-2 Mus musculus (Mouse) camera-type eye photoreceptor cell differentiation [GO:0060219]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; retina layer formation [GO:0010842]; synapse assembly [GO:0007416] GO:0005886; GO:0007156; GO:0007416; GO:0010842; GO:0045202; GO:0060219 37641 XM_044309225.1 147 42 46 215 158 Q6V4S5 5.3e-32 Protein sidekick-2 Mus musculus (Mouse) camera-type eye photoreceptor cell differentiation [GO:0060219]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; retina layer formation [GO:0010842]; synapse assembly [GO:0007416] GO:0005886; GO:0007156; GO:0007416; GO:0010842; GO:0045202; GO:0060219 37642 XM_044309225.1 147 42 46 215 158 Q6V4S5 1.29e-28 Protein sidekick-2 Mus musculus (Mouse) camera-type eye photoreceptor cell differentiation [GO:0060219]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; retina layer formation [GO:0010842]; synapse assembly [GO:0007416] GO:0005886; GO:0007156; GO:0007416; GO:0010842; GO:0045202; GO:0060219 37643 XM_044314741.1 745 261 213 333 588 NA NA NA NA NA NA 37644 XM_029357719.2 949 914 517 959 1199 Q13217 1.28e-166 DnaJ homolog subfamily C member 3 (Endoplasmic reticulum DNA J domain-containing protein 6) (ER-resident protein ERdj6) (ERdj6) (Interferon-induced, double-stranded RNA-activated protein kinase inhibitor) (Protein kinase inhibitor of 58 kDa) (Protein kinase inhibitor p58) Homo sapiens (Human) cellular response to cold [GO:0070417]; defense response to virus [GO:0051607]; negative regulation of apoptotic process [GO:0043066]; negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation [GO:1903912]; positive regulation of translation initiation in response to endoplasmic reticulum stress [GO:0036494]; protein folding in endoplasmic reticulum [GO:0034975]; proteolysis involved in protein catabolic process [GO:0051603]; response to unfolded protein [GO:0006986] GO:0004860; GO:0005576; GO:0005737; GO:0005783; GO:0005788; GO:0005790; GO:0005829; GO:0006986; GO:0016020; GO:0019901; GO:0034975; GO:0035578; GO:0036494; GO:0043066; GO:0051087; GO:0051603; GO:0051607; GO:0051787; GO:0070062; GO:0070417; GO:1903561; GO:1903912 37645 XR_006398050.1 843 32 35 33 340 NA NA NA NA NA NA 37646 XR_006395420.1 45 24 47 22 90 P99177 4.57e-27 Probable cysteine desulfurase (EC 2.8.1.7) Staphylococcus aureus (strain N315) cysteine metabolic process [GO:0006534] GO:0006534; GO:0030170; GO:0031071 37647 XM_044311855.1 2486 3813 4025 6166 1344 P27012 6.09e-30 S-crystallin 4 (OL4) Enteroctopus dofleini (North Pacific giant octopus) (Octopus dofleini) NA GO:0005212 37648 XM_044319699.1 52 28 33 34 14 E7FAM5 9.47e-84 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 37649 XM_029326371.2 6 0 5 0 7 NA NA NA NA NA NA 37650 XM_029344476.2 2084 2312 1369 1520 1049 NA NA NA NA NA NA 37651 XM_029352525.2 120 103 23 31 40 Q9P2K3 6.11e-112 REST corepressor 3 Homo sapiens (Human) histone deacetylation [GO:0016575]; negative regulation of DNA-templated transcription [GO:0045892]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000118; GO:0003714; GO:0005654; GO:0005667; GO:0005829; GO:0006357; GO:0016575; GO:0045892 37652 XR_006392017.1 11 3 0 0 0 NA NA NA NA NA NA 37653 XM_044308238.1 215 14 68 11 180 NA NA NA NA NA NA 37654 XM_044314053.1 62 23 60 46 3 Q8N0W3 0 L-fucose kinase (Fucokinase) (EC 2.7.1.52) Homo sapiens (Human) carbohydrate phosphorylation [GO:0046835]; GDP-L-fucose salvage [GO:0042352]; response to dopamine [GO:1903350] GO:0005524; GO:0005829; GO:0042352; GO:0046835; GO:0050201; GO:1903350 37655 XM_044313117.1 125 33 31 19 32 Q6H601 4.47e-23 DEAD-box ATP-dependent RNA helicase 22 (EC 3.6.4.13) Oryza sativa subsp. japonica (Rice) NA GO:0003723; GO:0003724; GO:0005524; GO:0016887 37656 XM_044310220.1 10 1 0 0 0 NA NA NA NA NA NA 37657 XM_044311321.1 0 0 5 0 12 NA NA NA NA NA NA 37658 XM_044314962.1 73 36 30 14 24 NA NA NA NA NA NA 37659 XM_044316113.1 29 1 5 18 13 Q64WY5 5.88e-106 Probable endonuclease 4 (EC 3.1.21.2) (Endodeoxyribonuclease IV) (Endonuclease IV) Bacteroides fragilis (strain YCH46) DNA repair [GO:0006281] GO:0003677; GO:0006281; GO:0008270; GO:0008833 37660 XM_044310263.1 15 23 0 41 33 Q5F371 0 Protein strawberry notch homolog 1 Gallus gallus (Chicken) regulation of DNA-templated transcription [GO:0006355]; regulation of response to stimulus [GO:0048583] GO:0005634; GO:0006355; GO:0031490; GO:0042393; GO:0048583 37661 XR_006392410.1 25 0 44 0 56 NA NA NA NA NA NA 37662 XM_044307838.1 913 1001 532 2094 799 NA NA NA NA NA NA 37663 XM_044318752.1 0 0 0 32 172 NA NA NA NA NA NA 37664 XM_044317938.1 85 177 107 100 108 NA NA NA NA NA NA 37665 XM_029344561.2 217 311 89 264 183 Q91VL8 7.2e-33 Telomeric repeat-binding factor 2-interacting protein 1 (TERF2-interacting telomeric protein 1) (TRF2-interacting telomeric protein 1) (Repressor/activator protein 1 homolog) (RAP1 homolog) Mus musculus (Mouse) negative regulation of DNA recombination at telomere [GO:0048239]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of telomere maintenance [GO:0032205]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein acetylation [GO:1901985]; positive regulation of telomere maintenance [GO:0032206]; protein localization to chromosome, telomeric region [GO:0070198]; regulation of DNA-templated transcription [GO:0006355]; regulation of double-strand break repair via homologous recombination [GO:0010569]; regulation of telomere maintenance [GO:0032204]; telomere capping [GO:0016233]; telomere maintenance [GO:0000723]; telomere maintenance via telomere lengthening [GO:0010833] GO:0000723; GO:0000781; GO:0000783; GO:0001673; GO:0001933; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006355; GO:0010569; GO:0010833; GO:0016233; GO:0016604; GO:0019902; GO:0032204; GO:0032205; GO:0032206; GO:0033138; GO:0042162; GO:0043123; GO:0048239; GO:0051092; GO:0070187; GO:0070198; GO:0098505; GO:1901224; GO:1901985 37666 XM_044327871.1 860 360 869 768 928 NA NA NA NA NA NA 37667 XM_029348070.2 38 8 55 7 73 NA NA NA NA NA NA 37668 XM_044310509.1 9 15 13 6 46 NA NA NA NA NA NA 37669 XR_006396329.1 10 9 393 1684 58 NA NA NA NA NA NA 37670 XM_029340064.2 1297 1164 538 953 780 NA NA NA NA NA NA 37671 XM_044311379.1 96 17 40 67 53 NA NA NA NA NA NA 37672 XM_029343834.2 1272 1338 431 876 786 NA NA NA NA NA NA 37673 XM_029344967.2 1756 1000 838 972 1038 Q9NWT6 5.29e-141 Hypoxia-inducible factor 1-alpha inhibitor (EC 1.14.11.30) (EC 1.14.11.n4) (Factor inhibiting HIF-1) (FIH-1) (Hypoxia-inducible factor asparagine hydroxylase) Homo sapiens (Human) negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061428]; peptidyl-aspartic acid hydroxylation [GO:0042264]; peptidyl-histidine hydroxylation [GO:0036138]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of vasculogenesis [GO:2001214] GO:0005112; GO:0005654; GO:0005737; GO:0005829; GO:0008198; GO:0008270; GO:0016706; GO:0019826; GO:0031406; GO:0036138; GO:0036139; GO:0036140; GO:0042264; GO:0042803; GO:0043433; GO:0045663; GO:0045746; GO:0048471; GO:0051059; GO:0061428; GO:0062101; GO:0071532; GO:2001214 37674 XM_029348104.2 94 20 67 41 56 P47793 1.47e-129 Protein Wnt-4a Danio rerio (Zebrafish) (Brachydanio rerio) canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; cell migration involved in gastrulation [GO:0042074]; embryonic viscerocranium morphogenesis [GO:0048703]; habenula development [GO:0021986]; heart development [GO:0007507]; neuron differentiation [GO:0030182]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of axon extension involved in axon guidance [GO:0048841]; sensory epithelium regeneration [GO:0070654] GO:0005109; GO:0005125; GO:0005615; GO:0007507; GO:0021986; GO:0030182; GO:0042074; GO:0045165; GO:0045893; GO:0048703; GO:0048841; GO:0060070; GO:0070654 37675 XR_006395254.1 17 0 14 14 9 NA NA NA NA NA NA 37676 XM_044325627.1 0 0 0 31 0 Q9HAR2 1e-58 Adhesion G protein-coupled receptor L3 (Calcium-independent alpha-latrotoxin receptor 3) (CIRL-3) (Latrophilin-3) (Lectomedin-3) Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; brain development [GO:0007420]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; G protein-coupled receptor signaling pathway [GO:0007186]; neuron migration [GO:0001764]; synapse assembly [GO:0007416] GO:0001764; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007166; GO:0007186; GO:0007189; GO:0007416; GO:0007420; GO:0016020; GO:0030246; GO:0030424; GO:0098742; GO:0098978 37677 XM_029357553.2 549 240 248 469 483 Q96AY4 5.93e-58 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 37678 XM_029357553.2 549 240 248 469 483 Q96AY4 5.82e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 37679 XM_029326957.2 4 0 20 18 60 P27590 8.4e-33 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Rattus norvegicus (Rat) antibacterial innate immune response [GO:0140367]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; autophagy [GO:0006914]; calcium ion homeostasis [GO:0055074]; cellular calcium ion homeostasis [GO:0006874]; cellular chloride ion homeostasis [GO:0030644]; cellular phosphate ion homeostasis [GO:0030643]; cellular response to unfolded protein [GO:0034620]; cellular sodium ion homeostasis [GO:0006883]; chaperone-mediated protein folding [GO:0061077]; chemical homeostasis [GO:0048878]; chloride ion homeostasis [GO:0055064]; citric acid secretion [GO:0046720]; collecting duct development [GO:0072044]; connective tissue replacement [GO:0097709]; creatinine homeostasis [GO:0097273]; defense response to Gram-negative bacterium [GO:0050829]; endoplasmic reticulum organization [GO:0007029]; gene expression [GO:0010467]; glomerular filtration [GO:0003094]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; ion homeostasis [GO:0050801]; juxtaglomerular apparatus development [GO:0072051]; kidney development [GO:0001822]; leukocyte cell-cell adhesion [GO:0007159]; lipid metabolic process [GO:0006629]; loop of Henle development [GO:0072070]; metanephric ascending thin limb development [GO:0072218]; metanephric distal convoluted tubule development [GO:0072221]; metanephric thick ascending limb development [GO:0072233]; micturition [GO:0060073]; multicellular organismal homeostasis [GO:0048871]; multicellular organismal response to stress [GO:0033555]; neutrophil migration [GO:1990266]; organ or tissue specific immune response [GO:0002251]; peptidyl-threonine phosphorylation [GO:0018107]; phosphate ion homeostasis [GO:0055062]; potassium ion homeostasis [GO:0055075]; protein localization to vacuole [GO:0072665]; protein phosphorylation [GO:0006468]; protein transport into plasma membrane raft [GO:0044861]; regulation of blood pressure [GO:0008217]; regulation of protein transport [GO:0051223]; regulation of urine volume [GO:0035809]; renal sodium ion absorption [GO:0070294]; renal urate salt excretion [GO:0097744]; renal water homeostasis [GO:0003091]; response to endoplasmic reticulum stress [GO:0034976]; response to lipopolysaccharide [GO:0032496]; response to organic substance [GO:0010033]; response to unfolded protein [GO:0006986]; response to water deprivation [GO:0009414]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; sodium ion homeostasis [GO:0055078]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; ubiquitin-dependent ERAD pathway [GO:0030433]; urate transport [GO:0015747]; urea transmembrane transport [GO:0071918]; water homeostasis [GO:0030104] GO:0000922; GO:0001822; GO:0002251; GO:0003091; GO:0003094; GO:0005201; GO:0005509; GO:0005615; GO:0005783; GO:0005794; GO:0005886; GO:0005929; GO:0006468; GO:0006629; GO:0006874; GO:0006883; GO:0006914; GO:0006915; GO:0006954; GO:0006986; GO:0007029; GO:0007157; GO:0007159; GO:0008217; GO:0008380; GO:0009410; GO:0009414; GO:0009986; GO:0010033; GO:0010467; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0018107; GO:0019864; GO:0030104; GO:0030433; GO:0030643; GO:0030644; GO:0031410; GO:0032496; GO:0033209; GO:0033555; GO:0034620; GO:0034976; GO:0035809; GO:0044861; GO:0045121; GO:0045177; GO:0046720; GO:0048871; GO:0048878; GO:0050801; GO:0050829; GO:0051223; GO:0055062; GO:0055064; GO:0055074; GO:0055075; GO:0055078; GO:0060073; GO:0060170; GO:0061077; GO:0070294; GO:0071918; GO:0072044; GO:0072051; GO:0072070; GO:0072218; GO:0072221; GO:0072233; GO:0072665; GO:0097190; GO:0097273; GO:0097709; GO:0097744; GO:0140367; GO:1990266 37680 XM_029357220.2 367 19 218 161 45 P49288 5.29e-24 Melatonin receptor type 1C (Mel-1C-R) (Mel1c receptor) (CKB) Gallus gallus (Chicken) G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of glucose import [GO:0046325]; negative regulation of glycolytic process [GO:0045820] GO:0004930; GO:0005654; GO:0005886; GO:0007186; GO:0008502; GO:0045820; GO:0046325; GO:1904408 37681 XM_044325199.1 0 43 108 0 0 NA NA NA NA NA NA 37682 XM_029358600.2 1006 504 318 447 509 P70665 3.48e-131 Sialate O-acetylesterase (EC 3.1.1.53) (Sialic acid-specific 9-O-acetylesterase) (Yolk sac protein 2) [Cleaved into: Sialate O-acetylesterase small subunit; Sialate O-acetylesterase large subunit] Mus musculus (Mouse) carbohydrate metabolic process [GO:0005975]; regulation of immune system process [GO:0002682] GO:0001681; GO:0002682; GO:0005764; GO:0005975; GO:0106330; GO:0106331 37683 XM_029324225.2 27 2 26 24 80 NA NA NA NA NA NA 37684 XM_029345342.2 935 1000 318 811 555 D4ACN8 2.12e-37 Plasminogen receptor (KT) (Plg-R(KT)) Rattus norvegicus (Rat) chemotaxis [GO:0006935]; inflammatory response [GO:0006954]; positive regulation of plasminogen activation [GO:0010756] GO:0005886; GO:0006935; GO:0006954; GO:0010756 37685 XR_006395235.1 62 34 13 29 29 NA NA NA NA NA NA 37686 XM_029344608.2 314 54 143 128 150 Q0D4Z6 1.57e-51 Indole-3-acetic acid-amido synthetase GH3.8 (EC 6.3.2.-) (Auxin-responsive GH3-like protein 8) (OsGH3-8) (OsMGH3) Oryza sativa subsp. japonica (Rice) auxin homeostasis [GO:0010252]; defense response [GO:0006952]; pollen development [GO:0009555]; regulation of defense response to bacterium [GO:1900424] GO:0005737; GO:0006952; GO:0009555; GO:0010252; GO:0010279; GO:0016208; GO:0016881; GO:1900424 37687 XM_029334016.2 171 81 74 44 162 D2IYS2 1.57e-64 Tyrosine-protein kinase receptor torso (EC 2.7.10.1) Bombyx mori (Silk moth) NA GO:0004714; GO:0005524; GO:0005886; GO:0046872 37688 XM_044318870.1 1781 1436 914 1370 905 Q9BSW2 4.38e-55 EF-hand calcium-binding domain-containing protein 4B (Calcium release-activated calcium channel regulator 2A) (CRAC channel regulator 2A) (Calcium release-activated channel regulator 2A) (Ras-related protein Rab-46) Homo sapiens (Human) activation of store-operated calcium channel activity [GO:0032237]; endosomal transport [GO:0016197]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of JNK cascade [GO:0046330]; response to histamine [GO:0034776]; store-operated calcium entry [GO:0002115]; T-helper 1 cell differentiation [GO:0045063] GO:0000139; GO:0001772; GO:0002115; GO:0003924; GO:0005509; GO:0005525; GO:0005576; GO:0005737; GO:0005815; GO:0005886; GO:0016020; GO:0016197; GO:0031982; GO:0032237; GO:0032588; GO:0033093; GO:0034776; GO:0035580; GO:0045063; GO:0046330; GO:0051928 37689 XM_044318870.1 1781 1436 914 1370 905 Q9BSW2 5.61e-36 EF-hand calcium-binding domain-containing protein 4B (Calcium release-activated calcium channel regulator 2A) (CRAC channel regulator 2A) (Calcium release-activated channel regulator 2A) (Ras-related protein Rab-46) Homo sapiens (Human) activation of store-operated calcium channel activity [GO:0032237]; endosomal transport [GO:0016197]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of JNK cascade [GO:0046330]; response to histamine [GO:0034776]; store-operated calcium entry [GO:0002115]; T-helper 1 cell differentiation [GO:0045063] GO:0000139; GO:0001772; GO:0002115; GO:0003924; GO:0005509; GO:0005525; GO:0005576; GO:0005737; GO:0005815; GO:0005886; GO:0016020; GO:0016197; GO:0031982; GO:0032237; GO:0032588; GO:0033093; GO:0034776; GO:0035580; GO:0045063; GO:0046330; GO:0051928 37690 XM_029349926.2 2 3 0 7 4 P49286 1.03e-25 Melatonin receptor type 1B (Mel-1B-R) (Mel1b receptor) Homo sapiens (Human) camera-type eye development [GO:0043010]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; glucose homeostasis [GO:0042593]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of insulin secretion [GO:0046676]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transmission of nerve impulse [GO:0051970]; negative regulation of vasoconstriction [GO:0045906]; positive regulation of circadian sleep/wake cycle, non-REM sleep [GO:0046010]; positive regulation of transmission of nerve impulse [GO:0051971]; regulation of insulin secretion [GO:0050796]; regulation of neuronal action potential [GO:0098908] GO:0004930; GO:0005886; GO:0007186; GO:0007187; GO:0007268; GO:0008502; GO:0010754; GO:0042593; GO:0043010; GO:0043524; GO:0045202; GO:0045906; GO:0046010; GO:0046676; GO:0050796; GO:0051481; GO:0051970; GO:0051971; GO:0098908; GO:1902260 37691 XM_029326925.2 42 34 8 39 30 P08510 4.14e-102 Potassium voltage-gated channel protein Shaker (Protein minisleep) Drosophila melanogaster (Fruit fly) action potential [GO:0001508]; axon extension [GO:0048675]; behavioral response to ether [GO:0048150]; cellular response to dopamine [GO:1903351]; courtship behavior [GO:0007619]; detection of visible light [GO:0009584]; larval locomotory behavior [GO:0008345]; learning or memory [GO:0007611]; mating behavior, sex discrimination [GO:0048047]; positive regulation of circadian sleep/wake cycle, sleep [GO:0045938]; positive regulation of membrane potential [GO:0045838]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; proboscis extension reflex [GO:0007637]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; regulation of ion transmembrane transport [GO:0034765]; regulation of synaptic activity [GO:0060025]; sensory perception of taste [GO:0050909]; sleep [GO:0030431] GO:0001508; GO:0005249; GO:0005251; GO:0006813; GO:0007611; GO:0007619; GO:0007637; GO:0008076; GO:0008345; GO:0009584; GO:0016020; GO:0022843; GO:0030431; GO:0034765; GO:0045187; GO:0045838; GO:0045938; GO:0048047; GO:0048150; GO:0048675; GO:0050909; GO:0051260; GO:0060025; GO:0071805; GO:1903351 37692 XM_044312356.1 455 303 340 128 143 Q3B7T1 0 Erythroid differentiation-related factor 1 Homo sapiens (Human) positive regulation of DNA-templated transcription [GO:0045893] GO:0005634; GO:0045893 37693 XM_044328291.1 568 543 267 335 950 P17844 0 Probable ATP-dependent RNA helicase DDX5 (EC 3.6.4.13) (DEAD box protein 5) (RNA helicase p68) Homo sapiens (Human) alternative mRNA splicing, via spliceosome [GO:0000380]; androgen receptor signaling pathway [GO:0030521]; BMP signaling pathway [GO:0030509]; epithelial to mesenchymal transition [GO:0001837]; intracellular estrogen receptor signaling pathway [GO:0030520]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; miRNA transcription [GO:0061614]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transcription [GO:0009299]; myoblast differentiation [GO:0045445]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nuclear-transcribed mRNA catabolic process [GO:0000956]; positive regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043517]; primary miRNA processing [GO:0031053]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of osteoblast differentiation [GO:0045667]; regulation of skeletal muscle cell differentiation [GO:2001014]; regulation of transcription by RNA polymerase II [GO:0006357]; rhythmic process [GO:0048511] GO:0000122; GO:0000380; GO:0000381; GO:0000398; GO:0000956; GO:0001837; GO:0003723; GO:0003724; GO:0003730; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005829; GO:0006357; GO:0009299; GO:0016020; GO:0016607; GO:0016887; GO:0030509; GO:0030520; GO:0030521; GO:0031053; GO:0035500; GO:0036002; GO:0043021; GO:0043517; GO:0045445; GO:0045667; GO:0046332; GO:0048511; GO:0050681; GO:0060765; GO:0061614; GO:0070062; GO:0070412; GO:0070878; GO:0071013; GO:0072332; GO:1990841; GO:1990904; GO:2001014 37694 XR_006394416.1 16 17 16 46 26 NA NA NA NA NA NA 37695 XM_044326691.1 846 1291 1768 1423 0 NA NA NA NA NA NA 37696 XM_029351040.2 380 71 169 71 274 Q8NDA2 1.01e-22 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 37697 XR_003828181.2 8 1 2 12 28 NA NA NA NA NA NA 37698 XM_029355442.2 9447 7209 4356 6292 6239 NA NA NA NA NA NA 37699 XM_029351831.2 179 104 124 161 196 P91309 0 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase (EC 2.7.4.24) (InsP6 and PP-IP5 kinase) Caenorhabditis elegans inositol metabolic process [GO:0006020]; inositol phosphate biosynthetic process [GO:0032958]; phosphorylation [GO:0016310] GO:0000827; GO:0000828; GO:0000829; GO:0000832; GO:0005524; GO:0005737; GO:0005829; GO:0006020; GO:0016310; GO:0032958; GO:0033857; GO:0052723; GO:0052724 37700 XM_029333985.2 0 26 142 0 0 NA NA NA NA NA NA 37701 XM_029350081.2 46 36 41 37 99 NA NA NA NA NA NA 37702 XM_044325672.1 754 0 3 1 189 NA NA NA NA NA NA 37703 XM_044309210.1 560 256 188 515 582 Q7Z494 0 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 37704 XM_044309210.1 560 256 188 515 582 Q7Z494 2.85e-21 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 37705 XM_044309210.1 560 256 188 515 582 Q7Z494 3.61e-21 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 37706 XM_044321431.1 77873 104980 161919 202899 135716 NA NA NA NA NA NA 37707 XM_029339327.2 220 167 110 350 225 NA NA NA NA NA NA 37708 XM_044309107.1 4 0 0 115 0 NA NA NA NA NA NA 37709 XM_029331130.2 5 3 10 0 20 O64411 1.51e-67 Polyamine oxidase 1 (EC 1.5.3.14) (EC 1.5.3.15) Zea mays (Maize) polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208] GO:0006598; GO:0009505; GO:0016491; GO:0046208; GO:0046592; GO:0048046; GO:0050660; GO:0052893; GO:0052896; GO:0052897; GO:0052900 37710 XM_044320589.1 545 160 119 447 318 NA NA NA NA NA NA 37711 XM_044320963.1 128 23 12 0 0 NA NA NA NA NA NA 37712 XM_044318960.1 260 29 75 62 317 Q3ZCC3 9.42e-112 TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6) Bos taurus (Bovine) activation of NF-kappaB-inducing kinase activity [GO:0007250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; bone resorption [GO:0045453]; cellular response to DNA damage stimulus [GO:0006974]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; in utero embryonic development [GO:0001701]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-17-mediated signaling pathway [GO:0097400]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin production [GO:0002637]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000122; GO:0001503; GO:0001701; GO:0001843; GO:0002637; GO:0002726; GO:0004842; GO:0005164; GO:0005634; GO:0005811; GO:0005829; GO:0005938; GO:0006974; GO:0007249; GO:0007250; GO:0008270; GO:0009898; GO:0019886; GO:0030316; GO:0031435; GO:0031624; GO:0031625; GO:0031663; GO:0031666; GO:0031996; GO:0032735; GO:0032743; GO:0032755; GO:0032813; GO:0033209; GO:0035631; GO:0042088; GO:0042102; GO:0042475; GO:0042802; GO:0042826; GO:0042981; GO:0043011; GO:0043122; GO:0043123; GO:0043422; GO:0043507; GO:0045453; GO:0045672; GO:0045944; GO:0046330; GO:0047485; GO:0048471; GO:0050852; GO:0051092; GO:0051865; GO:0061630; GO:0070498; GO:0070534; GO:0097400; GO:1901224; GO:1904996; GO:2000679 37713 XM_044326648.1 2 3 0 6 6 NA NA NA NA NA NA 37714 XM_044317462.1 1 13 1 7 11 NA NA NA NA NA NA 37715 XM_029349913.2 229 588 487 445 363 NA NA NA NA NA NA 37716 XR_003824265.2 7 7 7 7 0 NA NA NA NA NA NA 37717 XR_006396877.1 85 23 95 46 394 NA NA NA NA NA NA 37718 XM_029353703.2 2 0 2 7 88 P07949 1.77e-83 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; axon guidance [GO:0007411]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; lymphocyte migration into lymphoid organs [GO:0097021]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; posterior midgut development [GO:0007497]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006468; GO:0006919; GO:0007156; GO:0007158; GO:0007165; GO:0007169; GO:0007411; GO:0007497; GO:0009410; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0038023; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0097021; GO:0098797; GO:2001241 37719 XM_044314792.1 12 0 0 1 11 NA NA NA NA NA NA 37720 XM_044318739.1 29 33 13 21 15 NA NA NA NA NA NA 37721 XM_029334599.2 5338 2041 2319 2526 4878 Q8IUK5 4.11e-48 Plexin domain-containing protein 1 (Tumor endothelial marker 3) (Tumor endothelial marker 7) Homo sapiens (Human) angiogenesis [GO:0001525]; spinal cord development [GO:0021510] GO:0001525; GO:0005576; GO:0005615; GO:0005737; GO:0005886; GO:0005923; GO:0021510; GO:0030425; GO:0043025; GO:0043235 37722 XM_044317644.1 0 17 0 0 0 Q66PG1 1.89e-41 Xylosyl- and glucuronyltransferase LARGE2s (EC 2.4.-.-) (Glycosyltransferase-like 1B) (LARGE xylosyl- and glucuronyltransferase 2) [Includes: Alpha-1,3-xylosyltransferase LARGE2 (EC 2.4.2.-); Beta-1,3-glucuronyltransferase LARGE2 (EC 2.4.1.-)] Danio rerio (Zebrafish) (Brachydanio rerio) protein glycosylation [GO:0006486]; protein O-linked mannosylation [GO:0035269] GO:0000139; GO:0005794; GO:0006486; GO:0015020; GO:0035269; GO:0042285; GO:0046872 37723 XR_006392974.1 41 2 25 5 151 NA NA NA NA NA NA 37724 XM_029355825.2 62 19 24 78 38 NA NA NA NA NA NA 37725 XM_029338475.2 0 0 287 0 344 NA NA NA NA NA NA 37726 XM_044324723.1 89 4 97 309 16 Q9H0K6 2.29e-31 Pseudouridylate synthase PUS7L (EC 5.4.99.-) (Pseudouridylate synthase 7 homolog-like protein) Homo sapiens (Human) mRNA processing [GO:0006397]; mRNA pseudouridine synthesis [GO:1990481]; pseudouridine synthesis [GO:0001522] GO:0001522; GO:0003723; GO:0005634; GO:0006397; GO:0009982; GO:1990481 37727 XR_006391969.1 0 0 18 0 0 NA NA NA NA NA NA 37728 XM_029339128.2 186 0 32 61 103 NA NA NA NA NA NA 37729 XR_006395685.1 118 91 113 106 174 NA NA NA NA NA NA 37730 XM_029351797.2 1903 1841 1202 1836 1454 Q8JZZ6 1.13e-91 AMMECR1-like protein Mus musculus (Mouse) NA GO:0005634 37731 XM_044319086.1 400 584 100 196 254 Q9QZ85 1.48e-50 Interferon-inducible GTPase 1 (EC 3.6.5.-) Mus musculus (Mouse) cellular response to interferon-beta [GO:0035458]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; regulation of autophagy [GO:0010506]; response to bacterium [GO:0009617] GO:0003924; GO:0005525; GO:0005737; GO:0005789; GO:0006952; GO:0009617; GO:0010506; GO:0019003; GO:0019221; GO:0020005; GO:0031965; GO:0032580; GO:0035458; GO:0042802; GO:0042832; GO:0045087; GO:0050829 37732 XM_029348410.2 268 349 611 1451 1836 NA NA NA NA NA NA 37733 XR_003827235.2 7 0 5 0 0 NA NA NA NA NA NA 37734 XM_029337396.2 102 114 83 173 134 NA NA NA NA NA NA 37735 XM_044325226.1 40 56 43 55 62 Q4LDE5 3.44e-28 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 37736 XM_029338243.2 719 787 355 695 1062 NA NA NA NA NA NA 37737 XM_044321259.1 706 398 316 585 570 Q5R724 3.98e-89 Transcription factor SPT20 homolog Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) gastrulation [GO:0007369] GO:0000124; GO:0003712; GO:0007369 37738 XR_006395975.1 0 42 0 0 0 NA NA NA NA NA NA 37739 XM_044323076.1 7 1 0 10 23 NA NA NA NA NA NA 37740 XM_029338503.2 0 23 0 64 23 NA NA NA NA NA NA 37741 XM_029346547.2 0 162 271 167 301 Q1LZA0 5.08e-153 GPI mannosyltransferase 3 (EC 2.4.1.-) (GPI mannosyltransferase III) (GPI-MT-III) (Phosphatidylinositol-glycan biosynthesis class B protein) (PIG-B) Bos taurus (Bovine) GPI anchor biosynthetic process [GO:0006506] GO:0000026; GO:0000030; GO:0005789; GO:0006506 37742 XM_044310059.1 40 13 23 41 22 NA NA NA NA NA NA 37743 XR_006397161.1 0 19 0 52 84 NA NA NA NA NA NA 37744 XM_029339433.2 1772 1274 1183 1786 1717 Q6ZQ58 1.28e-152 La-related protein 1 (La ribonucleoprotein domain family member 1) Mus musculus (Mouse) cell population proliferation [GO:0008283]; cellular response to rapamycin [GO:0072752]; mRNA stabilization [GO:0048255]; negative regulation of translation [GO:0017148]; negative regulation of translational initiation [GO:0045947]; positive regulation of macroautophagy [GO:0016239]; positive regulation of translation [GO:0045727]; positive regulation of translational initiation [GO:0045948]; positive regulation of viral genome replication [GO:0045070]; post-transcriptional regulation of gene expression [GO:0010608]; response to amino acid starvation [GO:1990928]; TOR signaling [GO:0031929]; TORC1 signaling [GO:0038202]; translational initiation [GO:0006413] GO:0000339; GO:0000340; GO:0003723; GO:0003730; GO:0005737; GO:0005829; GO:0005844; GO:0006413; GO:0008190; GO:0008283; GO:0008494; GO:0010494; GO:0010608; GO:0016239; GO:0017148; GO:0031369; GO:0031929; GO:0031931; GO:0038202; GO:0042788; GO:0043024; GO:0045070; GO:0045727; GO:0045947; GO:0045948; GO:0048027; GO:0048255; GO:0072752; GO:1990928 37745 XM_044324135.1 82 36 46 43 143 Q5XJY4 1.88e-54 Presenilins-associated rhomboid-like protein, mitochondrial (EC 3.4.21.105) (Mitochondrial intramembrane-cleaving protease PARL) [Cleaved into: P-beta (Pbeta)] Mus musculus (Mouse) membrane protein proteolysis [GO:0033619]; mitochondrial fusion [GO:0008053]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; proteolysis [GO:0006508]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of mitochondrion organization [GO:0010821]; regulation of protein targeting to mitochondrion [GO:1903214]; regulation of proteolysis [GO:0030162]; regulation of reactive oxygen species metabolic process [GO:2000377]; signal peptide processing [GO:0006465] GO:0004175; GO:0004252; GO:0005634; GO:0005739; GO:0005743; GO:0006465; GO:0006508; GO:0008053; GO:0010821; GO:0030162; GO:0033619; GO:0090201; GO:1903146; GO:1903214; GO:2000377; GO:2001243 37746 XM_029355851.2 74 62 41 72 99 NA NA NA NA NA NA 37747 XM_029350451.2 1292 1054 1081 1144 1058 Q66I21 0 2-aminomuconic semialdehyde dehydrogenase (EC 1.2.1.32) (Aldehyde dehydrogenase family 8 member A1) Danio rerio (Zebrafish) (Brachydanio rerio) L-kynurenine catabolic process [GO:0097053]; liver development [GO:0001889]; retinoic acid metabolic process [GO:0042573] GO:0001758; GO:0001889; GO:0005737; GO:0016620; GO:0042573; GO:0047102; GO:0097053 37748 XM_029324001.2 273 0 0 4 321 A8E7N9 9.1e-40 Growth/differentiation factor 6-B (GDF-6-B) (Growth differentiation factor 6b) (Protein dynamo) Danio rerio (Zebrafish) (Brachydanio rerio) positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; SMAD protein signal transduction [GO:0060395] GO:0005125; GO:0005615; GO:0008083; GO:0010862; GO:0060395 37749 XM_044307145.1 334 468 210 407 316 Q8T882 2.12e-32 Tauropine dehydrogenase (TaDH) (EC 1.5.1.23) (NAD: tauropine oxidoreductase) Arabella iricolor (Opal worm) NA GO:0050325 37750 XM_029340818.2 4460 4419 6334 4359 942 Q8K3C3 7.42e-67 Protein LZIC (Leucine zipper and CTNNBIP1 domain-containing protein) (Leucine zipper and ICAT homologous domain-containing protein) Mus musculus (Mouse) negative regulation of Wnt signaling pathway [GO:0030178] GO:0008013; GO:0030178 37751 XM_029329883.2 141 99 59 93 71 Q09470 2.48e-92 Potassium voltage-gated channel subfamily A member 1 (Voltage-gated K(+) channel HuKI) (Voltage-gated potassium channel HBK1) (Voltage-gated potassium channel subunit Kv1.1) Homo sapiens (Human) axon development [GO:0061564]; cell communication by electrical coupling [GO:0010644]; cellular response to magnesium ion [GO:0071286]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; corpus callosum development [GO:0022038]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; detection of mechanical stimulus involved in sensory perception of touch [GO:0050976]; hippocampus development [GO:0021766]; magnesium ion homeostasis [GO:0010960]; neuroblast proliferation [GO:0007405]; neuromuscular process [GO:0050905]; neuronal action potential [GO:0019228]; neuronal signal transduction [GO:0023041]; optic nerve development [GO:0021554]; positive regulation of voltage-gated potassium channel activity [GO:1903818]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; protein localization [GO:0008104]; regulation of membrane potential [GO:0042391]; regulation of muscle contraction [GO:0006937]; startle response [GO:0001964] GO:0001964; GO:0005249; GO:0005251; GO:0005267; GO:0005783; GO:0005829; GO:0005886; GO:0006813; GO:0006937; GO:0007268; GO:0007405; GO:0008076; GO:0008104; GO:0009986; GO:0010644; GO:0010960; GO:0015079; GO:0016020; GO:0016324; GO:0019228; GO:0021554; GO:0021766; GO:0021987; GO:0022038; GO:0023041; GO:0030054; GO:0030425; GO:0031410; GO:0033270; GO:0042391; GO:0042734; GO:0043025; GO:0043194; GO:0043204; GO:0043679; GO:0044224; GO:0044305; GO:0045202; GO:0045211; GO:0050905; GO:0050966; GO:0050976; GO:0051260; GO:0061564; GO:0070161; GO:0071286; GO:0071805; GO:0097718; GO:0098978; GO:0099508; GO:1903818; GO:1905030 37752 XM_029331526.2 395 222 171 501 169 Q96JM7 2.86e-130 Lethal(3)malignant brain tumor-like protein 3 (H-l(3)mbt-like protein 3) (L(3)mbt-like protein 3) (L3mbt-like 3) (MBT-1) Homo sapiens (Human) chromatin organization [GO:0006325]; erythrocyte maturation [GO:0043249]; granulocyte differentiation [GO:0030851]; macrophage differentiation [GO:0030225]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; regulation of DNA methylation-dependent heterochromatin formation [GO:0090308] GO:0003682; GO:0005634; GO:0005654; GO:0005730; GO:0006325; GO:0008270; GO:0030225; GO:0030851; GO:0042393; GO:0042802; GO:0043249; GO:0045892; GO:0090308; GO:0140034; GO:2000060 37753 XM_029345739.2 2318 1061 1299 2029 2113 Q9R226 2.75e-65 KH domain-containing, RNA-binding, signal transduction-associated protein 3 (RNA-binding protein Etoile) (Sam68-like mammalian protein 2) (SLM-2) Mus musculus (Mouse) mRNA processing [GO:0006397]; positive regulation of RNA splicing [GO:0033120]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of mRNA splicing, via spliceosome [GO:0048024] GO:0000381; GO:0003723; GO:0003727; GO:0003729; GO:0005634; GO:0005654; GO:0006397; GO:0017124; GO:0019904; GO:0032991; GO:0033120; GO:0042802; GO:0048024 37754 XM_029335057.2 871 508 566 876 593 F1SPM8 1.8e-122 AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1) Sus scrofa (Pig) endocytosis [GO:0006897]; positive regulation of Notch signaling pathway [GO:0045747]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of clathrin-dependent endocytosis [GO:2000369]; regulation of protein localization [GO:0032880] GO:0004674; GO:0005112; GO:0005524; GO:0005737; GO:0005905; GO:0006468; GO:0006897; GO:0019897; GO:0030136; GO:0031252; GO:0032880; GO:0035612; GO:0043195; GO:0045747; GO:0046777; GO:0050821; GO:0106310; GO:2000369 37755 XR_006392574.1 77 0 2 0 9 NA NA NA NA NA NA 37756 XM_044311366.1 1 0 0 7 2 NA NA NA NA NA NA 37757 XM_044315130.1 3479 964 62 1175 9 NA NA NA NA NA NA 37758 XM_029339825.2 24 32 0 17 0 NA NA NA NA NA NA 37759 XM_044307663.1 42 64 28 19 11 NA NA NA NA NA NA 37760 XM_044318791.1 0 41 0 42 0 Q96C34 5.13e-67 RUN domain-containing protein 1 Homo sapiens (Human) activation of GTPase activity [GO:0090630]; in utero embryonic development [GO:0001701] GO:0001701; GO:0005096; GO:0090630 37761 XM_029351898.2 1853 1270 971 1921 2523 P83510 2.22e-144 Traf2 and NCK-interacting protein kinase (EC 2.7.11.1) Mus musculus (Mouse) actin cytoskeleton reorganization [GO:0031532]; cytoskeleton organization [GO:0007010]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; microvillus assembly [GO:0030033]; neuron projection morphogenesis [GO:0048812]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein phosphorylation [GO:0001934]; protein autophosphorylation [GO:0046777]; protein localization to plasma membrane [GO:0072659]; protein phosphorylation [GO:0006468]; regulation of dendrite morphogenesis [GO:0048814]; regulation of MAPK cascade [GO:0043408]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; Wnt signaling pathway [GO:0016055] GO:0000165; GO:0001934; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0006468; GO:0007010; GO:0016055; GO:0016324; GO:0030033; GO:0031532; GO:0035556; GO:0043408; GO:0046330; GO:0046777; GO:0048471; GO:0048812; GO:0048814; GO:0050775; GO:0055037; GO:0072659; GO:0098696; GO:0098793; GO:0098978; GO:0099092; GO:0106310 37762 XM_029351898.2 1853 1270 971 1921 2523 P83510 1.87e-124 Traf2 and NCK-interacting protein kinase (EC 2.7.11.1) Mus musculus (Mouse) actin cytoskeleton reorganization [GO:0031532]; cytoskeleton organization [GO:0007010]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; microvillus assembly [GO:0030033]; neuron projection morphogenesis [GO:0048812]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein phosphorylation [GO:0001934]; protein autophosphorylation [GO:0046777]; protein localization to plasma membrane [GO:0072659]; protein phosphorylation [GO:0006468]; regulation of dendrite morphogenesis [GO:0048814]; regulation of MAPK cascade [GO:0043408]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; Wnt signaling pathway [GO:0016055] GO:0000165; GO:0001934; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0006468; GO:0007010; GO:0016055; GO:0016324; GO:0030033; GO:0031532; GO:0035556; GO:0043408; GO:0046330; GO:0046777; GO:0048471; GO:0048812; GO:0048814; GO:0050775; GO:0055037; GO:0072659; GO:0098696; GO:0098793; GO:0098978; GO:0099092; GO:0106310 37763 XM_029334504.2 151 7 105 61 315 Q9PVM0 3.94e-24 Homeobox protein otx5-A (Orthodenticle homolog 5-A) (Xotx5) Xenopus laevis (African clawed frog) anterior/posterior pattern specification [GO:0009952]; eye photoreceptor cell fate commitment [GO:0042706]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000981; GO:0003677; GO:0005634; GO:0009952; GO:0042706; GO:0045944 37764 XM_044326335.1 25 19 6 18 16 NA NA NA NA NA NA 37765 XM_029348074.2 527 296 329 289 168 NA NA NA NA NA NA 37766 XM_044307716.1 162 37 82 195 104 P12804 3.11e-38 Fibroleukin (Cytotoxic T-lymphocyte-specific protein) (Fibrinogen-like protein 2) (Prothrombinase) Mus musculus (Mouse) cytolysis [GO:0019835]; negative regulation of defense response to virus [GO:0050687]; negative regulation of dendritic cell antigen processing and presentation [GO:0002605]; negative regulation of macrophage antigen processing and presentation [GO:0002617]; negative regulation of memory T cell differentiation [GO:0043381]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291] GO:0002291; GO:0002605; GO:0002617; GO:0005102; GO:0005615; GO:0019835; GO:0043381; GO:0050687; GO:0062023 37767 XM_044307313.1 245 0 104 12 53 NA NA NA NA NA NA 37768 XM_029331261.2 214 76 92 87 123 P49326 4.27e-79 Flavin-containing monooxygenase 5 (FMO 5) (Baeyer-Villiger monooxygenase 1) (hBVMO1) (EC 1.14.13.-) (Dimethylaniline monooxygenase [N-oxide-forming] 5) (EC 1.14.13.8) (Dimethylaniline oxidase 5) (NADPH oxidase) (EC 1.6.3.1) Homo sapiens (Human) lipid metabolic process [GO:0006629]; NADPH oxidation [GO:0070995]; regulation of cholesterol metabolic process [GO:0090181]; xenobiotic metabolic process [GO:0006805] GO:0004031; GO:0004497; GO:0004499; GO:0005783; GO:0005789; GO:0005829; GO:0006629; GO:0006805; GO:0047822; GO:0050660; GO:0050661; GO:0070995; GO:0090181; GO:0106294 37769 XM_044322113.1 0 0 0 0 13 NA NA NA NA NA NA 37770 XM_044327712.1 461 247 254 482 803 NA NA NA NA NA NA 37771 XM_029336204.2 0 31 0 66 0 NA NA NA NA NA NA 37772 XM_044313136.1 2421 1641 908 3261 2041 Q9QXA6 4.9e-132 b(0,+)-type amino acid transporter 1 (b(0,+)AT1) (Glycoprotein-associated amino acid transporter b0,+AT1) (Solute carrier family 7 member 9) Mus musculus (Mouse) amino acid transport [GO:0006865]; L-cystine transport [GO:0015811]; neutral amino acid transport [GO:0015804] GO:0005886; GO:0006865; GO:0015171; GO:0015175; GO:0015179; GO:0015184; GO:0015804; GO:0015811; GO:0016324; GO:0031526; GO:0042605 37773 XM_044324486.1 102 1 33 20 220 NA NA NA NA NA NA 37774 XM_044314493.1 34 3 8 11 53 Q94K49 1.76e-23 Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1 (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) epigenetic regulation of gene expression [GO:0040029] GO:0003682; GO:0004518; GO:0005634; GO:0035098; GO:0035102; GO:0040029; GO:0046872 37775 XM_044319734.1 36 0 0 36 0 NA NA NA NA NA NA 37776 XM_044319110.1 759 84 299 629 122 NA NA NA NA NA NA 37777 XM_044311885.1 7 0 0 0 0 NA NA NA NA NA NA 37778 XM_029338129.2 193 10 85 43 123 P08510 1.34e-86 Potassium voltage-gated channel protein Shaker (Protein minisleep) Drosophila melanogaster (Fruit fly) action potential [GO:0001508]; axon extension [GO:0048675]; behavioral response to ether [GO:0048150]; cellular response to dopamine [GO:1903351]; courtship behavior [GO:0007619]; detection of visible light [GO:0009584]; larval locomotory behavior [GO:0008345]; learning or memory [GO:0007611]; mating behavior, sex discrimination [GO:0048047]; positive regulation of circadian sleep/wake cycle, sleep [GO:0045938]; positive regulation of membrane potential [GO:0045838]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; proboscis extension reflex [GO:0007637]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; regulation of ion transmembrane transport [GO:0034765]; regulation of synaptic activity [GO:0060025]; sensory perception of taste [GO:0050909]; sleep [GO:0030431] GO:0001508; GO:0005249; GO:0005251; GO:0006813; GO:0007611; GO:0007619; GO:0007637; GO:0008076; GO:0008345; GO:0009584; GO:0016020; GO:0022843; GO:0030431; GO:0034765; GO:0045187; GO:0045838; GO:0045938; GO:0048047; GO:0048150; GO:0048675; GO:0050909; GO:0051260; GO:0060025; GO:0071805; GO:1903351 37779 XM_029346842.2 4722 4712 2096 4802 2529 Q9IA79 3.18e-69 Probable Bax inhibitor 1 (BI-1) (Testis-enhanced gene transcript protein homolog) (Transmembrane BAX inhibitor motif-containing protein 6) Paralichthys olivaceus (Bastard halibut) (Hippoglossus olivaceus) apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; response to unfolded protein [GO:0006986] GO:0005789; GO:0006915; GO:0006986; GO:0043066 37780 XM_029344294.2 666 1220 534 1100 2183 Q6P8Y1 1.33e-62 Calcyphosin-like protein Mus musculus (Mouse) NA GO:0005509; GO:0005737 37781 XR_006397788.1 1120 1964 746 516 903 NA NA NA NA NA NA 37782 XM_029346499.2 318 1168 892 275 501 Q6DHQ1 2.12e-29 Voltage-gated hydrogen channel 1 (Hydrogen voltage-gated channel 1) (HV1) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to pH [GO:0071467]; cellular response to zinc ion [GO:0071294]; proton transmembrane transport [GO:1902600]; regulation of ion transmembrane transport [GO:0034765]; response to zinc ion [GO:0010043] GO:0005886; GO:0008270; GO:0010043; GO:0030171; GO:0034765; GO:0071294; GO:0071467; GO:1902600 37783 XM_029356659.2 2772 2630 1574 2544 1962 Q9QXN5 6.22e-123 Inositol oxygenase (EC 1.13.99.1) (Aldehyde reductase-like 6) (Myo-inositol oxygenase) (MI oxygenase) (Renal-specific oxidoreductase) Mus musculus (Mouse) inositol catabolic process [GO:0019310] GO:0004033; GO:0005737; GO:0008199; GO:0016234; GO:0016491; GO:0016651; GO:0016701; GO:0019310; GO:0050113; GO:0050661 37784 XM_029332691.2 77 99 71 111 233 NA NA NA NA NA NA 37785 XM_044325337.1 20 0 25 9 36 A6QLU6 1.73e-72 Adhesion G-protein coupled receptor D1 (G-protein coupled receptor 133) Bos taurus (Bovine) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0005886; GO:0007166; GO:0007186; GO:0007189 37786 XM_029352694.2 109 107 41 89 144 NA NA NA NA NA NA 37787 XM_029336149.2 1682 1408 1346 1981 1754 Q7KZ85 0 Transcription elongation factor SPT6 (hSPT6) (Histone chaperone suppressor of Ty6) (Tat-cotransactivator 2 protein) (Tat-CT2 protein) Homo sapiens (Human) blastocyst formation [GO:0001825]; mRNA processing [GO:0006397]; mRNA transcription by RNA polymerase II [GO:0042789]; mRNA transport [GO:0051028]; nucleosome organization [GO:0034728]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; regulation of isotype switching [GO:0045191]; regulation of mRNA export from nucleus [GO:0010793]; regulation of mRNA processing [GO:0050684]; regulation of muscle cell differentiation [GO:0051147]; RNA splicing [GO:0008380]; transcription elongation by RNA polymerase II promoter [GO:0006368]; transcription elongation-coupled chromatin remodeling [GO:0140673] GO:0001825; GO:0003677; GO:0003723; GO:0005654; GO:0006368; GO:0006397; GO:0008023; GO:0008380; GO:0010793; GO:0031491; GO:0032968; GO:0034728; GO:0042393; GO:0042789; GO:0045191; GO:0050684; GO:0051028; GO:0051147; GO:0140673 37788 XM_029330580.2 2718 1535 1147 2804 3255 Q9JHS4 0 ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial Mus musculus (Mouse) ATP metabolic process [GO:0046034]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603] GO:0004176; GO:0005524; GO:0005654; GO:0005739; GO:0005743; GO:0005759; GO:0005829; GO:0006508; GO:0008270; GO:0009368; GO:0009841; GO:0016504; GO:0016887; GO:0042645; GO:0046034; GO:0046983; GO:0051082; GO:0051603; GO:0140662 37789 XR_003825295.2 591 265 524 606 279 Q96DM1 1.01e-49 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 37790 XM_044309986.1 20 8 14 19 60 P19477 5.17e-46 Fibrinogen-like protein A (FREP-A) Apostichopus parvimensis (Warty sea cucumber) (Stichopus parvimensis) NA NA 37791 XM_044309862.1 95 10 188 14 1141 NA NA NA NA NA NA 37792 XM_044318127.1 3782 534 2908 2185 1560 Q6RI86 9.28e-120 Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Wasabi receptor) Rattus norvegicus (Rat) calcium ion transmembrane import into cytosol [GO:0097553]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cell surface receptor signaling pathway [GO:0007166]; cellular calcium ion homeostasis [GO:0006874]; cellular response to caffeine [GO:0071313]; cellular response to carbon dioxide [GO:0071244]; cellular response to cold [GO:0070417]; cellular response to heat [GO:0034605]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to organic substance [GO:0071310]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; ion transmembrane transport [GO:0034220]; positive regulation of anion transport [GO:1903793]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of sensory perception of pain [GO:1904058]; protein homotetramerization [GO:0051289]; regulation of blood circulation [GO:1903522]; regulation of neuronal action potential [GO:0098908]; response to cold [GO:0009409]; response to hydrogen peroxide [GO:0042542]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; sensory perception of pain [GO:0019233]; thermoception [GO:0050955]; transmembrane transport [GO:0055085]; urinary bladder smooth muscle contraction [GO:0014832] GO:0005216; GO:0005245; GO:0005262; GO:0005886; GO:0006816; GO:0006874; GO:0007166; GO:0009409; GO:0009410; GO:0010033; GO:0014070; GO:0014832; GO:0015267; GO:0015278; GO:0016324; GO:0019233; GO:0030424; GO:0032421; GO:0034220; GO:0034605; GO:0035774; GO:0042542; GO:0042802; GO:0048265; GO:0050955; GO:0050966; GO:0050968; GO:0050974; GO:0051289; GO:0055085; GO:0070301; GO:0070417; GO:0070588; GO:0071244; GO:0071310; GO:0071313; GO:0097553; GO:0097604; GO:0098908; GO:1903522; GO:1903793; GO:1904058; GO:1990760 37793 XM_029342410.2 2733 3180 1351 2586 1938 P83941 5.86e-65 Elongin-C (EloC) (Elongin 15 kDa subunit) (RNA polymerase II transcription factor SIII subunit C) (SIII p15) (Stromal membrane-associated protein SMAP1B homolog) (Transcription elongation factor B polypeptide 1) Rattus norvegicus (Rat) positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; protein ubiquitination [GO:0016567]; transcription initiation at RNA polymerase II promoter [GO:0006367]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0001222; GO:0006367; GO:0006511; GO:0016567; GO:0030674; GO:0030891; GO:0031466; GO:0032968; GO:0044877; GO:0070449 37794 XM_029353955.2 239 302 0 503 692 Q9K7A0 1.39e-29 Probable cysteine desulfurase (EC 2.8.1.7) Halalkalibacterium halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) (Bacillus halodurans) cysteine metabolic process [GO:0006534] GO:0006534; GO:0030170; GO:0031071 37795 XM_029349090.2 802 250 385 521 342 Q8BFR4 1.54e-168 N-acetylglucosamine-6-sulfatase (EC 3.1.6.14) (Glucosamine-6-sulfatase) (G6S) Mus musculus (Mouse) keratan sulfate catabolic process [GO:0042340] GO:0005539; GO:0005764; GO:0008449; GO:0008484; GO:0042340; GO:0043199; GO:0046872 37796 XM_044322615.1 388 149 466 187 1849 NA NA NA NA NA NA 37797 XR_006392952.1 41 2 25 5 151 NA NA NA NA NA NA 37798 XM_029324997.2 1038 1267 890 1340 942 NA NA NA NA NA NA 37799 XR_006397486.1 1 45 12 3 23 Q8BR93 4.79e-58 Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease) Mus musculus (Mouse) NA GO:0004518; GO:0005634; GO:0005829; GO:0005886; GO:0034451; GO:0046872 37800 XM_044312587.1 0 0 0 0 7 NA NA NA NA NA NA 37801 XM_029328758.2 10295 9442 8273 10821 6979 NA NA NA NA NA NA 37802 XM_044308375.1 15 0 9 17 38 A0JPE9 4.51e-159 Putative glycerol kinase 5 (GK 5) (Glycerokinase 5) (EC 2.7.1.30) (ATP:glycerol 3-phosphotransferase 5) Danio rerio (Zebrafish) (Brachydanio rerio) glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate biosynthetic process [GO:0046167]; phosphorylation [GO:0016310]; triglyceride metabolic process [GO:0006641] GO:0004370; GO:0005524; GO:0005739; GO:0006071; GO:0006641; GO:0016310; GO:0019563; GO:0046167 37803 XM_044314422.1 14 62 7 2 33 Q80XJ3 1.6e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 37804 XM_044323737.1 0 5 6 28 6 NA NA NA NA NA NA 37805 XM_029336182.2 6 0 384 410 168 Q61603 9.63e-66 Glycine receptor subunit alpha-4 Mus musculus (Mouse) chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; neuropeptide signaling pathway [GO:0007218]; regulation of membrane potential [GO:0042391]; response to amino acid [GO:0043200]; signal transduction [GO:0007165]; synaptic transmission, glycinergic [GO:0060012] GO:0004888; GO:0005231; GO:0005886; GO:0007165; GO:0007218; GO:0007268; GO:0016594; GO:0016934; GO:0030425; GO:0030594; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0043200; GO:0043204; GO:0045202; GO:0050877; GO:0060012; GO:0098690; GO:0099634; GO:1902476; GO:1904315 37806 XM_029352979.2 2 1 2 7 12 NA NA NA NA NA NA 37807 XM_044328149.1 0 0 353 0 0 O88974 8.16e-76 Histone-lysine N-methyltransferase SETDB1 (EC 2.1.1.366) (ERG-associated protein with SET domain) (ESET) (SET domain bifurcated 1) Mus musculus (Mouse) bone development [GO:0060348]; heterochromatin organization [GO:0070828]; histone H3-K9 methylation [GO:0051567]; inner cell mass cell proliferation [GO:0001833]; negative regulation of gene expression [GO:0010629]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA methylation-dependent heterochromatin formation [GO:0090309]; Ras protein signal transduction [GO:0007265] GO:0000122; GO:0001833; GO:0003677; GO:0003682; GO:0005634; GO:0005654; GO:0005694; GO:0005737; GO:0007265; GO:0008270; GO:0010629; GO:0018024; GO:0043231; GO:0045869; GO:0046974; GO:0051567; GO:0060348; GO:0070828; GO:0090309; GO:0140947; GO:0140948; GO:1990841 37808 XM_044328149.1 0 0 353 0 0 O88974 4.13e-50 Histone-lysine N-methyltransferase SETDB1 (EC 2.1.1.366) (ERG-associated protein with SET domain) (ESET) (SET domain bifurcated 1) Mus musculus (Mouse) bone development [GO:0060348]; heterochromatin organization [GO:0070828]; histone H3-K9 methylation [GO:0051567]; inner cell mass cell proliferation [GO:0001833]; negative regulation of gene expression [GO:0010629]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA methylation-dependent heterochromatin formation [GO:0090309]; Ras protein signal transduction [GO:0007265] GO:0000122; GO:0001833; GO:0003677; GO:0003682; GO:0005634; GO:0005654; GO:0005694; GO:0005737; GO:0007265; GO:0008270; GO:0010629; GO:0018024; GO:0043231; GO:0045869; GO:0046974; GO:0051567; GO:0060348; GO:0070828; GO:0090309; GO:0140947; GO:0140948; GO:1990841 37809 XM_044328149.1 0 0 353 0 0 O88974 4.17e-39 Histone-lysine N-methyltransferase SETDB1 (EC 2.1.1.366) (ERG-associated protein with SET domain) (ESET) (SET domain bifurcated 1) Mus musculus (Mouse) bone development [GO:0060348]; heterochromatin organization [GO:0070828]; histone H3-K9 methylation [GO:0051567]; inner cell mass cell proliferation [GO:0001833]; negative regulation of gene expression [GO:0010629]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA methylation-dependent heterochromatin formation [GO:0090309]; Ras protein signal transduction [GO:0007265] GO:0000122; GO:0001833; GO:0003677; GO:0003682; GO:0005634; GO:0005654; GO:0005694; GO:0005737; GO:0007265; GO:0008270; GO:0010629; GO:0018024; GO:0043231; GO:0045869; GO:0046974; GO:0051567; GO:0060348; GO:0070828; GO:0090309; GO:0140947; GO:0140948; GO:1990841 37810 XM_044323770.1 64 35 29 27 26 B8UU78 0 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 37811 XM_044323770.1 64 35 29 27 26 B8UU78 0 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 37812 XM_044320034.1 13 17 40 49 34 NA NA NA NA NA NA 37813 XM_029352616.2 46 71 37 79 87 NA NA NA NA NA NA 37814 XM_029327084.2 1164 797 859 1735 1099 Q8NEV4 0 Myosin-IIIa (EC 2.7.11.1) Homo sapiens (Human) cochlea morphogenesis [GO:0090103]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of filopodium assembly [GO:0051491]; protein autophosphorylation [GO:0046777]; regulation of actin filament length [GO:0030832]; response to stimulus [GO:0050896]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] GO:0000146; GO:0001917; GO:0003779; GO:0004672; GO:0004674; GO:0005516; GO:0005524; GO:0005737; GO:0007601; GO:0007605; GO:0016459; GO:0018105; GO:0030175; GO:0030832; GO:0031941; GO:0032426; GO:0032433; GO:0043531; GO:0046777; GO:0050896; GO:0051491; GO:0060002; GO:0090103; GO:0106310 37815 XM_029323556.2 0 0 0 19 0 NA NA NA NA NA NA 37816 XR_006392869.1 41 2 25 5 151 NA NA NA NA NA NA 37817 XM_029350587.2 12 0 0 63 0 Q6XP49 5e-74 Zinc finger protein GLIS3 (GLI-similar 3) Mus musculus (Mouse) negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366] GO:0000122; GO:0000977; GO:0000978; GO:0000981; GO:0001227; GO:0001228; GO:0003677; GO:0003700; GO:0005634; GO:0006357; GO:0006366; GO:0045944; GO:0046872 37818 XR_006395819.1 165 113 99 210 195 P69478 4.32e-39 Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4S-1) (C4ST-1) (C4ST1) Rattus norvegicus (Rat) apoptotic process [GO:0006915]; carbohydrate biosynthetic process [GO:0016051]; cartilage development [GO:0051216]; chondrocyte development [GO:0002063]; chondroitin sulfate biosynthetic process [GO:0030206]; chondroitin sulfate metabolic process [GO:0030204]; developmental growth [GO:0048589]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; embryonic viscerocranium morphogenesis [GO:0048703]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; polysaccharide localization [GO:0033037]; post-anal tail morphogenesis [GO:0036342]; post-embryonic development [GO:0009791]; proteoglycan biosynthetic process [GO:0030166]; regulation of cell population proliferation [GO:0042127]; respiratory gaseous exchange by respiratory system [GO:0007585]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0000139; GO:0001537; GO:0001701; GO:0002063; GO:0006915; GO:0007179; GO:0007585; GO:0008146; GO:0009791; GO:0016051; GO:0030166; GO:0030204; GO:0030206; GO:0030326; GO:0030512; GO:0033037; GO:0036342; GO:0042127; GO:0042733; GO:0043066; GO:0047756; GO:0048589; GO:0048703; GO:0048704; GO:0050659; GO:0051216 37819 XM_044324307.1 0 751 0 1165 371 Q92542 4.14e-129 Nicastrin Homo sapiens (Human) adult behavior [GO:0030534]; amyloid precursor protein biosynthetic process [GO:0042983]; amyloid precursor protein catabolic process [GO:0042987]; amyloid precursor protein metabolic process [GO:0042982]; amyloid-beta formation [GO:0034205]; cellular response to calcium ion [GO:0071277]; central nervous system myelination [GO:0022010]; cerebellum development [GO:0021549]; dopamine receptor signaling pathway [GO:0007212]; epithelial cell proliferation [GO:0050673]; glutamate receptor signaling pathway [GO:0007215]; learning or memory [GO:0007611]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; myeloid cell homeostasis [GO:0002262]; neuron apoptotic process [GO:0051402]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; positive regulation of amyloid precursor protein biosynthetic process [GO:0042986]; positive regulation of catalytic activity [GO:0043085]; positive regulation of endopeptidase activity [GO:0010950]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of long-term synaptic potentiation [GO:1900271]; short-term synaptic potentiation [GO:1990926]; T cell proliferation [GO:0042098] GO:0002262; GO:0005739; GO:0005765; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005925; GO:0006508; GO:0006509; GO:0007212; GO:0007215; GO:0007219; GO:0007220; GO:0007611; GO:0008021; GO:0010008; GO:0010950; GO:0016020; GO:0016485; GO:0021549; GO:0022010; GO:0030534; GO:0030674; GO:0031293; GO:0034205; GO:0035577; GO:0042098; GO:0042383; GO:0042470; GO:0042500; GO:0042734; GO:0042982; GO:0042983; GO:0042986; GO:0042987; GO:0043085; GO:0050673; GO:0051117; GO:0051402; GO:0070062; GO:0070765; GO:0070851; GO:0071277; GO:1900271; GO:1990926 37820 XM_044318502.1 562 271 352 241 125 Q924L9 9.67e-157 Folylpolyglutamate synthase, mitochondrial (EC 6.3.2.17) (Folylpoly-gamma-glutamate synthetase) (FPGS) (Tetrahydrofolate synthase) (Tetrahydrofolylpolyglutamate synthase) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) one-carbon metabolic process [GO:0006730] GO:0004326; GO:0005524; GO:0005743; GO:0005759; GO:0006730; GO:0046872 37821 XR_006394737.1 37 10 31 20 105 NA NA NA NA NA NA 37822 XM_029333320.2 373 211 293 541 0 Q12923 2.84e-57 Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1) (PTP-BAS) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (Protein-tyrosine phosphatase PTPL1) Homo sapiens (Human) cellular response to toxic substance [GO:0097237]; negative regulation of excitatory synapse assembly [GO:1904890]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066] GO:0001650; GO:0001933; GO:0004725; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0006470; GO:0014066; GO:0030027; GO:0035335; GO:0036312; GO:0043005; GO:0044297; GO:0070062; GO:0097237; GO:1904890 37823 XM_029333320.2 373 211 293 541 0 Q12923 1.66e-28 Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1) (PTP-BAS) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (Protein-tyrosine phosphatase PTPL1) Homo sapiens (Human) cellular response to toxic substance [GO:0097237]; negative regulation of excitatory synapse assembly [GO:1904890]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066] GO:0001650; GO:0001933; GO:0004725; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0006470; GO:0014066; GO:0030027; GO:0035335; GO:0036312; GO:0043005; GO:0044297; GO:0070062; GO:0097237; GO:1904890 37824 XM_044313081.1 319 28 218 162 155 Q7RTR2 6.82e-32 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 37825 XM_044313081.1 319 28 218 162 155 Q7RTR2 4.61e-28 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 37826 XM_044313081.1 319 28 218 162 155 Q7RTR2 1.72e-27 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 37827 XM_044313081.1 319 28 218 162 155 Q7RTR2 1.17e-26 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 37828 XM_044313081.1 319 28 218 162 155 Q7RTR2 9.32e-24 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 37829 XM_029356925.2 563 988 369 523 434 Q5R947 2.42e-132 U3 small nucleolar ribonucleoprotein protein IMP4 (U3 snoRNP protein IMP4) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) rRNA processing [GO:0006364] GO:0005730; GO:0006364; GO:0042134; GO:1990904 37830 XM_044312794.1 4 0 5 8 8 NA NA NA NA NA NA 37831 XM_029351147.2 3003 3925 1930 1119 1226 Q9DAM1 9.22e-103 Leucine-rich repeat-containing protein 34 Mus musculus (Mouse) cell differentiation [GO:0030154] GO:0005730; GO:0005737; GO:0030154 37832 XM_029357682.2 562 453 452 686 434 Q22460 5.43e-48 Beta carbonic anhydrase 1 (EC 4.2.1.1) Caenorhabditis elegans NA GO:0004089; GO:0008270 37833 XM_029342977.2 4 14 9 7 0 NA NA NA NA NA NA 37834 XM_029324952.2 12 26 28 23 30 NA NA NA NA NA NA 37835 XM_044318917.1 10 4 17 18 0 NA NA NA NA NA NA 37836 XM_029356627.2 30 42 46 70 58 NA NA NA NA NA NA 37837 XM_029344428.2 1288 1240 598 902 1510 Q8IWW6 2.3e-84 Rho GTPase-activating protein 12 (Rho-type GTPase-activating protein 12) Homo sapiens (Human) actin filament organization [GO:0007015]; morphogenesis of an epithelial sheet [GO:0002011]; negative regulation of small GTPase mediated signal transduction [GO:0051058]; phagocytosis, engulfment [GO:0006911]; regulation of GTPase activity [GO:0043087]; signal transduction [GO:0007165] GO:0001891; GO:0002011; GO:0005096; GO:0005737; GO:0006911; GO:0007015; GO:0007165; GO:0043087; GO:0051058 37838 XR_006393949.1 36 0 7 8 4 NA NA NA NA NA NA 37839 XM_029351805.2 1047 1068 673 1135 845 Q9H095 2e-83 Dynein regulatory complex protein 9 (IQ domain-containing protein G) Homo sapiens (Human) cilium organization [GO:0044782]; sperm axoneme assembly [GO:0007288]; spermatid development [GO:0007286] GO:0002177; GO:0005516; GO:0005737; GO:0005829; GO:0007286; GO:0007288; GO:0030544; GO:0031514; GO:0036126; GO:0044782; GO:0070062 37840 XM_044315934.1 7 7 21 18 16 NA NA NA NA NA NA 37841 XR_006395471.1 562 62 52 75 14 NA NA NA NA NA NA 37842 XR_006397896.1 23 31 5 4 18 NA NA NA NA NA NA 37843 XM_044313129.1 187 187 186 206 318 NA NA NA NA NA NA 37844 XR_006393014.1 0 0 0 0 92 NA NA NA NA NA NA 37845 XM_029357567.2 897 542 604 1546 831 D3ZEN0 5.97e-46 MICAL-like protein 2 (Junctional Rab13-binding protein) (Molecule interacting with CasL-like 2) (MICAL-L2) Rattus norvegicus (Rat) actin cytoskeleton reorganization [GO:0031532]; actin filament polymerization [GO:0030041]; bicellular tight junction assembly [GO:0070830]; endocytic recycling [GO:0032456]; neuron projection development [GO:0031175]; substrate adhesion-dependent cell spreading [GO:0034446] GO:0005829; GO:0005886; GO:0005911; GO:0005923; GO:0030041; GO:0031005; GO:0031175; GO:0031267; GO:0031532; GO:0032432; GO:0032456; GO:0034446; GO:0042805; GO:0043005; GO:0046872; GO:0051015; GO:0055037; GO:0070830 37846 XR_006392486.1 20 27 29 32 36 NA NA NA NA NA NA 37847 XM_029347287.2 3 0 32 13 16 NA NA NA NA NA NA 37848 XM_044319226.1 507 468 40 1314 770 NA NA NA NA NA NA 37849 XM_029356073.2 35 2 3 1 4 NA NA NA NA NA NA 37850 XM_044317600.1 12 45 49 66 101 NA NA NA NA NA NA 37851 XM_029325740.2 978 18 33 27 58 Q8K3Z0 1.96e-30 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 37852 XM_044324870.1 28 4 7 0 60 NA NA NA NA NA NA 37853 XM_044320939.1 838 448 365 580 585 NA NA NA NA NA NA 37854 XM_044319987.1 41 4 0 7 24 NA NA NA NA NA NA 37855 XM_044307730.1 0 0 22 6 122 NA NA NA NA NA NA 37856 XR_006395722.1 0 22 1 0 17 NA NA NA NA NA NA 37857 XM_044316455.1 6 0 16 23 33 NA NA NA NA NA NA 37858 XR_006392079.1 28 17 1 10 8 NA NA NA NA NA NA 37859 XM_044323130.1 16 22 39 18 58 NA NA NA NA NA NA 37860 XM_029341828.2 65 9 0 8 13 NA NA NA NA NA NA 37861 XM_044313400.1 28 4 18 12 19 P04323 1.61e-66 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 37862 XM_044309725.1 4 13 0 8 11 P0CT39 4.82e-75 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 37863 XM_044309227.1 2 7 2 8 39 NA NA NA NA NA NA 37864 XM_029330174.2 116 0 1468 229 2911 A4UTP7 2.65e-63 Myocyte-specific enhancer factor 2C Sus scrofa (Pig) B cell homeostasis [GO:0001782]; B cell proliferation [GO:0042100]; B cell receptor signaling pathway [GO:0050853]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cardiac ventricle formation [GO:0003211]; cardiocyte differentiation [GO:0035051]; cellular response to calcium ion [GO:0071277]; cellular response to fluid shear stress [GO:0071498]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cellular response to trichostatin A [GO:0035984]; cellular response to xenobiotic stimulus [GO:0071466]; chondrocyte differentiation [GO:0002062]; endochondral ossification [GO:0001958]; epithelial cell proliferation involved in renal tubule morphogenesis [GO:2001013]; germinal center formation [GO:0002467]; glomerulus morphogenesis [GO:0072102]; heart development [GO:0007507]; heart looping [GO:0001947]; humoral immune response [GO:0006959]; learning or memory [GO:0007611]; MAPK cascade [GO:0000165]; melanocyte differentiation [GO:0030318]; muscle cell fate determination [GO:0007521]; negative regulation of gene expression [GO:0010629]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of ossification [GO:0030279]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nephron tubule epithelial cell differentiation [GO:0072160]; neural crest cell differentiation [GO:0014033]; neuron development [GO:0048666]; neuron differentiation [GO:0030182]; osteoblast differentiation [GO:0001649]; outflow tract morphogenesis [GO:0003151]; platelet formation [GO:0030220]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of behavioral fear response [GO:2000987]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cardiac muscle cell differentiation [GO:2000727]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of macrophage apoptotic process [GO:2000111]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of skeletal muscle cell differentiation [GO:2001016]; positive regulation of skeletal muscle tissue development [GO:0048643]; positive regulation of transcription by RNA polymerase II [GO:0045944]; primary heart field specification [GO:0003138]; regulation of germinal center formation [GO:0002634]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of synaptic activity [GO:0060025]; regulation of transcription by RNA polymerase II [GO:0006357]; renal tubule morphogenesis [GO:0061333]; secondary heart field specification [GO:0003139]; sinoatrial valve morphogenesis [GO:0003185]; skeletal muscle tissue development [GO:0007519]; smooth muscle cell differentiation [GO:0051145]; ventricular cardiac muscle cell differentiation [GO:0055012] GO:0000122; GO:0000165; GO:0000976; GO:0000977; GO:0000978; GO:0000981; GO:0001228; GO:0001568; GO:0001649; GO:0001782; GO:0001947; GO:0001958; GO:0001974; GO:0002062; GO:0002467; GO:0002634; GO:0003138; GO:0003139; GO:0003151; GO:0003185; GO:0003211; GO:0003677; GO:0003700; GO:0005634; GO:0005737; GO:0006357; GO:0006959; GO:0007507; GO:0007519; GO:0007521; GO:0007611; GO:0010628; GO:0010629; GO:0010694; GO:0014033; GO:0016528; GO:0016607; GO:0030182; GO:0030220; GO:0030279; GO:0030318; GO:0030501; GO:0030890; GO:0032991; GO:0035051; GO:0035984; GO:0042100; GO:0043524; GO:0045652; GO:0045663; GO:0045666; GO:0045669; GO:0045893; GO:0045944; GO:0046983; GO:0048643; GO:0048666; GO:0050853; GO:0051145; GO:0055012; GO:0060025; GO:0060045; GO:0061333; GO:0071222; GO:0071277; GO:0071374; GO:0071466; GO:0071498; GO:0071560; GO:0072102; GO:0072160; GO:2000111; GO:2000727; GO:2000987; GO:2001013; GO:2001016 37865 XM_044312811.1 89 89 38 82 81 Q92900 3.94e-77 Regulator of nonsense transcripts 1 (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up-frameshift suppressor 1 homolog) (hUpf1) Homo sapiens (Human) 3'-UTR-mediated mRNA destabilization [GO:0061158]; cell cycle phase transition [GO:0044770]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; DNA duplex unwinding [GO:0032508]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; histone mRNA catabolic process [GO:0071044]; mRNA export from nucleus [GO:0006406]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay [GO:0000294]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of mRNA catabolic process [GO:0061014]; regulation of telomere maintenance [GO:0032204]; regulation of translational termination [GO:0006449]; telomere maintenance via semi-conservative replication [GO:0032201] GO:0000184; GO:0000294; GO:0000781; GO:0000785; GO:0000932; GO:0000956; GO:0003682; GO:0003723; GO:0003724; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006260; GO:0006281; GO:0006406; GO:0006449; GO:0008270; GO:0016887; GO:0032201; GO:0032204; GO:0032508; GO:0035145; GO:0036121; GO:0042162; GO:0044530; GO:0044770; GO:0044877; GO:0048471; GO:0061014; GO:0061158; GO:0071044; GO:0071222; GO:0071347 37866 XM_044321574.1 333 85 4492 413 440 NA NA NA NA NA NA 37867 XM_044329149.1 0 0 0 0 15 NA NA NA NA NA NA 37868 XM_044310614.1 539 108 116 262 115 P31836 4.02e-23 Neural cell adhesion molecule 1 (N-CAM-1) (NCAM-1) Bos taurus (Bovine) axon guidance [GO:0007411]; dendrite self-avoidance [GO:0070593]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005886; GO:0007156; GO:0007411; GO:0030424; GO:0070593; GO:0098632 37869 XM_044314959.1 4 0 7 1 8 B8UU78 1.26e-180 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 37870 XM_029336421.2 54 31 0 0 31 NA NA NA NA NA NA 37871 XR_006397340.1 0 1 0 6 4 NA NA NA NA NA NA 37872 XM_029332896.2 3936 4072 2420 4784 7174 NA NA NA NA NA NA 37873 XM_044326923.1 74 91 159 581 159 NA NA NA NA NA NA 37874 XM_044326890.1 100 8 77 22 264 P10079 2.6e-91 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37875 XM_044326890.1 100 8 77 22 264 P10079 6.3e-87 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37876 XM_044326890.1 100 8 77 22 264 P10079 4.1e-84 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37877 XM_044326890.1 100 8 77 22 264 P10079 1.05e-82 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37878 XM_044326890.1 100 8 77 22 264 P10079 8.55e-81 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37879 XM_044314964.1 55 20 2 3 51 NA NA NA NA NA NA 37880 XM_029355923.2 507 673 330 273 568 NA NA NA NA NA NA 37881 XM_044327840.1 114 352 106 100 63 NA NA NA NA NA NA 37882 XM_044328969.1 62 48 76 67 201 NA NA NA NA NA NA 37883 XM_044325829.1 2545 4247 2881 3130 2838 P59708 1.32e-69 Splicing factor 3B subunit 6 (Pre-mRNA branch site protein p14) (SF3b 14 kDa subunit) Mus musculus (Mouse) blastocyst formation [GO:0001825]; mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0001825; GO:0003729; GO:0005634; GO:0005654; GO:0005684; GO:0005686; GO:0005689; GO:0071011; GO:0071013 37884 XM_029332967.2 115 0 69 133 253 Q5ZLD7 0 Vacuolar protein sorting-associated protein 53 homolog Gallus gallus (Chicken) endocytic recycling [GO:0032456]; protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147] GO:0000938; GO:0005829; GO:0010008; GO:0015031; GO:0032456; GO:0042147; GO:0055037; GO:1990745 37885 XR_003825902.2 82 36 43 34 153 P91660 2.63e-36 Probable multidrug resistance-associated protein lethal(2)03659 (Wunen region A protein) Drosophila melanogaster (Fruit fly) organic anion transport [GO:0015711]; transmembrane transport [GO:0055085] GO:0005524; GO:0008514; GO:0015562; GO:0015711; GO:0016020; GO:0016887; GO:0042626; GO:0055085; GO:0140359 37886 XR_006393722.1 85 654 310 448 627 NA NA NA NA NA NA 37887 XM_044323669.1 2 0 0 0 28 NA NA NA NA NA NA 37888 XM_044322269.1 379 115 484 241 484 NA NA NA NA NA NA 37889 XM_044327250.1 570 487 377 569 589 P50867 1.64e-136 Cysteine synthase 1 (CS 1) (EC 2.5.1.-) (EC 2.5.1.47) (O-acetylserine (thiol)-lyase 1) (OAS-TL 1) (O-acetylserine sulfhydrylase 1) (O-succinylserine sulfhydrylase) Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) amino acid biosynthetic process [GO:0008652]; cysteine biosynthetic process [GO:0019344]; cysteine biosynthetic process from serine [GO:0006535] GO:0004124; GO:0005737; GO:0005739; GO:0006535; GO:0008652; GO:0019344 37890 XM_029329076.2 2397 1328 1258 1735 1826 A2RV61 3.95e-112 GTPase-activating protein and VPS9 domain-containing protein 1 Xenopus laevis (African clawed frog) endocytosis [GO:0006897]; regulation of GTPase activity [GO:0043087]; regulation of protein transport [GO:0051223] GO:0005085; GO:0005096; GO:0005768; GO:0005829; GO:0006897; GO:0016020; GO:0032794; GO:0043087; GO:0051223 37891 XM_029329076.2 2397 1328 1258 1735 1826 A2RV61 2.15e-61 GTPase-activating protein and VPS9 domain-containing protein 1 Xenopus laevis (African clawed frog) endocytosis [GO:0006897]; regulation of GTPase activity [GO:0043087]; regulation of protein transport [GO:0051223] GO:0005085; GO:0005096; GO:0005768; GO:0005829; GO:0006897; GO:0016020; GO:0032794; GO:0043087; GO:0051223 37892 XM_044320437.1 91 808 422 139 763 NA NA NA NA NA NA 37893 XM_044313143.1 3 1 10 0 0 NA NA NA NA NA NA 37894 XM_029339029.2 781 907 411 754 781 Q9DCL2 1.28e-54 Cytosolic iron-sulfur assembly component 2A (MIP18 family protein FAM96A) Mus musculus (Mouse) chromosome segregation [GO:0007059]; iron-sulfur cluster assembly [GO:0016226]; protein maturation by [4Fe-4S] cluster transfer [GO:0106035]; protein maturation by iron-sulfur cluster transfer [GO:0097428] GO:0005654; GO:0005829; GO:0007059; GO:0016226; GO:0046872; GO:0097361; GO:0097428; GO:0106035 37895 XM_029331473.2 0 8 0 0 12 Q9D2U5 4.06e-27 N-alpha-acetyltransferase 38, NatC auxiliary subunit (LSM domain-containing protein 1) Mus musculus (Mouse) negative regulation of apoptotic process [GO:0043066] GO:0005634; GO:0005654; GO:0005737; GO:0005844; GO:0031417; GO:0043066 37896 XM_044321707.1 92 37 20 76 129 NA NA NA NA NA NA 37897 XM_029337450.2 12 0 25 0 6 Q9DCV4 4.62e-70 Regulator of microtubule dynamics protein 1 (RMD-1) (mRMD-1) (Microtubule-associated protein) (Protein FAM82B) Mus musculus (Mouse) NA GO:0005737; GO:0005739; GO:0005876; GO:0008017; GO:0097431 37898 XM_029356962.2 585 304 194 133 505 Q8TD16 4.78e-128 Protein bicaudal D homolog 2 (Bic-D 2) Homo sapiens (Human) centrosome localization [GO:0051642]; microtubule anchoring at microtubule organizing center [GO:0072393]; microtubule-based movement [GO:0007018]; minus-end-directed organelle transport along microtubule [GO:0072385]; mRNA transport [GO:0051028]; protein localization to Golgi apparatus [GO:0034067]; protein localization to organelle [GO:0033365]; protein transport [GO:0015031]; regulation of microtubule cytoskeleton organization [GO:0070507]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] GO:0005635; GO:0005642; GO:0005643; GO:0005737; GO:0005794; GO:0005813; GO:0005829; GO:0005886; GO:0006890; GO:0007018; GO:0008093; GO:0015031; GO:0031267; GO:0031410; GO:0033365; GO:0034067; GO:0034452; GO:0051028; GO:0051642; GO:0051959; GO:0070507; GO:0070840; GO:0072385; GO:0072393 37899 XR_006397537.1 10 17 24 9 69 NA NA NA NA NA NA 37900 XR_003825599.2 46 0 31 23 28 NA NA NA NA NA NA 37901 XM_044309877.1 0 0 0 8 0 NA NA NA NA NA NA 37902 XR_003825140.2 10985 17135 11511 17231 6460 NA NA NA NA NA NA 37903 XM_029330269.2 7 0 6 5 37 Q6PH18 3.55e-112 Nuclear receptor subfamily 2 group F member 1-B (COUP transcription factor 1-B) (COUP-TFalpha-B) Danio rerio (Zebrafish) (Brachydanio rerio) anatomical structure development [GO:0048856]; angioblast cell migration [GO:0035476]; cell differentiation [GO:0030154]; cranial skeletal system development [GO:1904888]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; vasculature development [GO:0001944]; venous blood vessel development [GO:0060841] GO:0000122; GO:0000978; GO:0001944; GO:0004879; GO:0005634; GO:0006357; GO:0008270; GO:0030154; GO:0035476; GO:0045944; GO:0048856; GO:0060841; GO:1904888 37904 XR_003826630.2 1509 3197 1588 4460 1278 NA NA NA NA NA NA 37905 XM_044312112.1 58 4 52 9 40 P04323 4.15e-61 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 37906 XR_006394564.1 8 0 0 0 0 NA NA NA NA NA NA 37907 XM_029337615.2 178 7 42 27 30 Q8R151 0 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 37908 XM_029337615.2 178 7 42 27 30 Q8R151 5.95e-76 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 37909 XM_029346863.2 0 0 97 0 142 P48058 8.83e-94 Glutamate receptor 4 (GluR-4) (GluR4) (AMPA-selective glutamate receptor 4) (GluR-D) (Glutamate receptor ionotropic, AMPA 4) (GluA4) Homo sapiens (Human) glutamate receptor signaling pathway [GO:0007215]; negative regulation of smooth muscle cell apoptotic process [GO:0034392] GO:0001540; GO:0004970; GO:0004971; GO:0005886; GO:0007215; GO:0015276; GO:0030666; GO:0032281; GO:0034392; GO:0038023; GO:0043025; GO:0043197; GO:0045211; GO:0099507; GO:1903561 37910 XM_044314851.1 117 88 75 120 65 E1BY51 1.89e-47 Transmembrane protein 17 Gallus gallus (Chicken) cilium assembly [GO:0060271]; non-motile cilium assembly [GO:1905515]; smoothened signaling pathway [GO:0007224] GO:0007224; GO:0035869; GO:0036038; GO:0060170; GO:0060271; GO:1905515 37911 XM_044312579.1 577 501 579 280 2234 NA NA NA NA NA NA 37912 XM_044311445.1 0 6 0 22 0 NA NA NA NA NA NA 37913 XM_029355707.2 388 207 238 634 471 P28818 0 Ras-specific guanine nucleotide-releasing factor 1 (Ras-GRF1) (Guanine nucleotide-releasing protein) (GNRP) (P140 Ras-GRF) Rattus norvegicus (Rat) activation of GTPase activity [GO:0090630]; cell population proliferation [GO:0008283]; cellular response to antibiotic [GO:0071236]; cellular response to insulin stimulus [GO:0032869]; neuron projection development [GO:0031175]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of GTPase activity [GO:0043547]; positive regulation of Ras protein signal transduction [GO:0046579]; Ras protein signal transduction [GO:0007265]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of NMDA receptor activity [GO:2000310]; regulation of Rac protein signal transduction [GO:0035020]; regulation of Ras protein signal transduction [GO:0046578]; regulation of synaptic plasticity [GO:0048167]; response to amphetamine [GO:0001975]; response to endoplasmic reticulum stress [GO:0034976]; type B pancreatic cell proliferation [GO:0044342] GO:0001975; GO:0005085; GO:0005096; GO:0005737; GO:0005829; GO:0005886; GO:0007265; GO:0008022; GO:0008283; GO:0016323; GO:0016327; GO:0019901; GO:0030426; GO:0030971; GO:0031175; GO:0031267; GO:0032869; GO:0034976; GO:0035020; GO:0035254; GO:0043025; GO:0043547; GO:0044342; GO:0046578; GO:0046579; GO:0048146; GO:0048167; GO:0048168; GO:0071236; GO:0090630; GO:0097440; GO:2000310 37914 XM_029355707.2 388 207 238 634 471 P28818 8.53e-100 Ras-specific guanine nucleotide-releasing factor 1 (Ras-GRF1) (Guanine nucleotide-releasing protein) (GNRP) (P140 Ras-GRF) Rattus norvegicus (Rat) activation of GTPase activity [GO:0090630]; cell population proliferation [GO:0008283]; cellular response to antibiotic [GO:0071236]; cellular response to insulin stimulus [GO:0032869]; neuron projection development [GO:0031175]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of GTPase activity [GO:0043547]; positive regulation of Ras protein signal transduction [GO:0046579]; Ras protein signal transduction [GO:0007265]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of NMDA receptor activity [GO:2000310]; regulation of Rac protein signal transduction [GO:0035020]; regulation of Ras protein signal transduction [GO:0046578]; regulation of synaptic plasticity [GO:0048167]; response to amphetamine [GO:0001975]; response to endoplasmic reticulum stress [GO:0034976]; type B pancreatic cell proliferation [GO:0044342] GO:0001975; GO:0005085; GO:0005096; GO:0005737; GO:0005829; GO:0005886; GO:0007265; GO:0008022; GO:0008283; GO:0016323; GO:0016327; GO:0019901; GO:0030426; GO:0030971; GO:0031175; GO:0031267; GO:0032869; GO:0034976; GO:0035020; GO:0035254; GO:0043025; GO:0043547; GO:0044342; GO:0046578; GO:0046579; GO:0048146; GO:0048167; GO:0048168; GO:0071236; GO:0090630; GO:0097440; GO:2000310 37915 XR_006393995.1 52 6 76 16 128 NA NA NA NA NA NA 37916 XR_006392537.1 6 106 32 153 21 NA NA NA NA NA NA 37917 XM_044312765.1 372 272 287 281 397 A4IGM4 1.29e-56 Hydroxysteroid 11-beta-dehydrogenase 1-like protein (EC 1.1.1.-) (11-beta-hydroxysteroid dehydrogenase type 3) (11-DH3) (11-beta-HSD3) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005576; GO:0016491 37918 XM_044326984.1 184 49 56 146 102 NA NA NA NA NA NA 37919 XM_029343037.2 53 0 7 33 108 NA NA NA NA NA NA 37920 XM_029357825.2 696 453 421 806 784 Q9P1Z9 5.1e-108 Coiled-coil domain-containing protein 180 Homo sapiens (Human) NA GO:0070062 37921 XM_029357825.2 696 453 421 806 784 Q9P1Z9 2.34e-68 Coiled-coil domain-containing protein 180 Homo sapiens (Human) NA GO:0070062 37922 XM_044318804.1 843 538 648 1032 816 P59470 0 DNA-directed RNA polymerase III subunit RPC2 (RNA polymerase III subunit C2) (EC 2.7.7.6) (C128) (DNA-directed RNA polymerase III 127.6 kDa polypeptide) (DNA-directed RNA polymerase III subunit B) Mus musculus (Mouse) defense response to virus [GO:0051607]; DNA-templated transcription [GO:0006351]; innate immune response [GO:0045087]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-beta production [GO:0032728] GO:0003677; GO:0003899; GO:0005666; GO:0006351; GO:0032549; GO:0032728; GO:0045087; GO:0045089; GO:0046872; GO:0051607 37923 XM_044316942.1 283 101 201 242 356 Q2YDF6 5.16e-58 28S ribosomal protein S35, mitochondrial (MRP-S35) (S35mt) (28S ribosomal protein S28, mitochondrial) (MRP-S28) (S28mt) Bos taurus (Bovine) mitochondrial translation [GO:0032543] GO:0003735; GO:0005743; GO:0005763; GO:0032543 37924 XM_029332994.2 2792 4288 2661 4226 3648 Q32NT4 2.86e-78 Leucine-rich repeat-containing protein 58 Xenopus laevis (African clawed frog) NA NA 37925 XR_006397077.1 13 19 41 21 49 NA NA NA NA NA NA 37926 XM_044326615.1 0 0 11 0 0 NA NA NA NA NA NA 37927 XM_044315092.1 2405 2354 1338 1804 2452 Q6NZJ6 1.52e-98 Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G 1) (eIF-4G1) Mus musculus (Mouse) behavioral fear response [GO:0001662]; cellular macromolecule biosynthetic process [GO:0034645]; cellular response to nutrient levels [GO:0031669]; energy homeostasis [GO:0097009]; lung development [GO:0030324]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of autophagy [GO:0010507]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; neuron differentiation [GO:0030182]; positive regulation of cell death [GO:0010942]; positive regulation of cell growth [GO:0030307]; positive regulation of eukaryotic translation initiation factor 4F complex assembly [GO:1905537]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of mRNA cap binding [GO:1905612]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of translation in response to endoplasmic reticulum stress [GO:0036493]; regulation of polysome binding [GO:1905696]; regulation of presynapse assembly [GO:1905606]; regulation of translational initiation [GO:0006446]; response to ethanol [GO:0045471]; translation [GO:0006412]; translational initiation [GO:0006413] GO:0001662; GO:0003729; GO:0003743; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0005844; GO:0006412; GO:0006413; GO:0006446; GO:0008135; GO:0008190; GO:0010494; GO:0010507; GO:0010801; GO:0010942; GO:0016281; GO:0030182; GO:0030307; GO:0030324; GO:0031669; GO:0033138; GO:0034645; GO:0035278; GO:0036493; GO:0042802; GO:0045471; GO:0045666; GO:0051247; GO:0097009; GO:0098794; GO:1900087; GO:1905537; GO:1905606; GO:1905612; GO:1905696 37928 XM_044315092.1 2405 2354 1338 1804 2452 Q6NZJ6 1.52e-55 Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G 1) (eIF-4G1) Mus musculus (Mouse) behavioral fear response [GO:0001662]; cellular macromolecule biosynthetic process [GO:0034645]; cellular response to nutrient levels [GO:0031669]; energy homeostasis [GO:0097009]; lung development [GO:0030324]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of autophagy [GO:0010507]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; neuron differentiation [GO:0030182]; positive regulation of cell death [GO:0010942]; positive regulation of cell growth [GO:0030307]; positive regulation of eukaryotic translation initiation factor 4F complex assembly [GO:1905537]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of mRNA cap binding [GO:1905612]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of translation in response to endoplasmic reticulum stress [GO:0036493]; regulation of polysome binding [GO:1905696]; regulation of presynapse assembly [GO:1905606]; regulation of translational initiation [GO:0006446]; response to ethanol [GO:0045471]; translation [GO:0006412]; translational initiation [GO:0006413] GO:0001662; GO:0003729; GO:0003743; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0005844; GO:0006412; GO:0006413; GO:0006446; GO:0008135; GO:0008190; GO:0010494; GO:0010507; GO:0010801; GO:0010942; GO:0016281; GO:0030182; GO:0030307; GO:0030324; GO:0031669; GO:0033138; GO:0034645; GO:0035278; GO:0036493; GO:0042802; GO:0045471; GO:0045666; GO:0051247; GO:0097009; GO:0098794; GO:1900087; GO:1905537; GO:1905606; GO:1905612; GO:1905696 37929 XR_003826165.2 0 0 7 0 4 NA NA NA NA NA NA 37930 XM_044314230.1 26 7 26 9 1209 B0BN95 1.84e-33 Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease) Rattus norvegicus (Rat) NA GO:0004518; GO:0005634; GO:0005737; GO:0046872 37931 XM_044315302.1 153 16 120 33 419 NA NA NA NA NA NA 37932 XM_029351131.2 237 263 214 242 329 Q9WV70 4.4e-136 Nucleolar complex protein 2 homolog (Protein NOC2 homolog) (NOC2-like protein) (Novel INHAT repressor) Mus musculus (Mouse) apoptotic process [GO:0006915]; cellular response to UV [GO:0034644]; negative regulation of B cell apoptotic process [GO:0002903]; negative regulation of histone acetylation [GO:0035067]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of transcription by RNA polymerase II [GO:0000122]; ribosomal large subunit biogenesis [GO:0042273]; transcription initiation-coupled chromatin remodeling [GO:0045815] GO:0000122; GO:0000786; GO:0002039; GO:0002903; GO:0003682; GO:0003714; GO:0005634; GO:0005654; GO:0005694; GO:0005730; GO:0005829; GO:0006915; GO:0030690; GO:0030691; GO:0031491; GO:0034644; GO:0035067; GO:0042273; GO:0042393; GO:0045815; GO:0140297; GO:2001243 37933 XM_044312995.1 0 0 13 5 35 Q60997 9.09e-34 Deleted in malignant brain tumors 1 protein (Apactin) (CRP-ductin) (Glycoprotein 300) (gp300) (Hensin) (Mucin-like glycoprotein) (Muclin) (Vomeroglandin) (p80) Mus musculus (Mouse) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blastocyst development [GO:0001824]; columnar/cuboidal epithelial cell differentiation [GO:0002065]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterial lipoprotein [GO:0042494]; induction of bacterial agglutination [GO:0043152]; inner cell mass cell proliferation [GO:0001833]; positive regulation of epithelial cell differentiation [GO:0030858]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617] GO:0001530; GO:0001824; GO:0001833; GO:0002065; GO:0003677; GO:0005044; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0009617; GO:0015031; GO:0019898; GO:0030658; GO:0030670; GO:0030858; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0050829; GO:0050830; GO:0050840; GO:0061844; GO:0062023; GO:0070891; GO:1904399 37934 XM_044312995.1 0 0 13 5 35 Q60997 9.16e-30 Deleted in malignant brain tumors 1 protein (Apactin) (CRP-ductin) (Glycoprotein 300) (gp300) (Hensin) (Mucin-like glycoprotein) (Muclin) (Vomeroglandin) (p80) Mus musculus (Mouse) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blastocyst development [GO:0001824]; columnar/cuboidal epithelial cell differentiation [GO:0002065]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterial lipoprotein [GO:0042494]; induction of bacterial agglutination [GO:0043152]; inner cell mass cell proliferation [GO:0001833]; positive regulation of epithelial cell differentiation [GO:0030858]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617] GO:0001530; GO:0001824; GO:0001833; GO:0002065; GO:0003677; GO:0005044; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0009617; GO:0015031; GO:0019898; GO:0030658; GO:0030670; GO:0030858; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0050829; GO:0050830; GO:0050840; GO:0061844; GO:0062023; GO:0070891; GO:1904399 37935 XM_044312995.1 0 0 13 5 35 Q60997 1.9e-28 Deleted in malignant brain tumors 1 protein (Apactin) (CRP-ductin) (Glycoprotein 300) (gp300) (Hensin) (Mucin-like glycoprotein) (Muclin) (Vomeroglandin) (p80) Mus musculus (Mouse) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blastocyst development [GO:0001824]; columnar/cuboidal epithelial cell differentiation [GO:0002065]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterial lipoprotein [GO:0042494]; induction of bacterial agglutination [GO:0043152]; inner cell mass cell proliferation [GO:0001833]; positive regulation of epithelial cell differentiation [GO:0030858]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617] GO:0001530; GO:0001824; GO:0001833; GO:0002065; GO:0003677; GO:0005044; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0009617; GO:0015031; GO:0019898; GO:0030658; GO:0030670; GO:0030858; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0050829; GO:0050830; GO:0050840; GO:0061844; GO:0062023; GO:0070891; GO:1904399 37936 XM_044316521.1 6184 5591 3067 5642 5666 Q9VVE5 8.07e-28 RNA-binding protein Musashi homolog Rbp6 Drosophila melanogaster (Fruit fly) regulation of translation [GO:0006417]; stem cell development [GO:0048864] GO:0003727; GO:0003729; GO:0005737; GO:0005844; GO:0006417; GO:0008266; GO:0048864 37937 XM_044316521.1 6184 5591 3067 5642 5666 Q9VVE5 1.1e-22 RNA-binding protein Musashi homolog Rbp6 Drosophila melanogaster (Fruit fly) regulation of translation [GO:0006417]; stem cell development [GO:0048864] GO:0003727; GO:0003729; GO:0005737; GO:0005844; GO:0006417; GO:0008266; GO:0048864 37938 XR_003827056.2 27 0 22 18 29 NA NA NA NA NA NA 37939 XR_003826855.2 18 3 17 11 3 NA NA NA NA NA NA 37940 XM_044310489.1 19 70 15 546 22 NA NA NA NA NA NA 37941 XM_029346416.2 382 250 354 318 604 Q9JIL9 9.7e-54 Nibrin (Nijmegen breakage syndrome protein 1 homolog) Rattus norvegicus (Rat) blastocyst growth [GO:0001832]; cell population proliferation [GO:0008283]; DNA damage checkpoint signaling [GO:0000077]; DNA duplex unwinding [GO:0032508]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; in utero embryonic development [GO:0001701]; intrinsic apoptotic signaling pathway [GO:0097193]; isotype switching [GO:0045190]; meiotic cell cycle [GO:0051321]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of telomere capping [GO:1904354]; negative regulation of viral entry into host cell [GO:0046597]; neuroblast proliferation [GO:0007405]; neuromuscular process controlling balance [GO:0050885]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of kinase activity [GO:0033674]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of telomere maintenance [GO:0032206]; regulation of fibroblast proliferation [GO:0048145]; response to xenobiotic stimulus [GO:0009410]; t-circle formation [GO:0090656]; telomere maintenance [GO:0000723]; telomere maintenance via telomere trimming [GO:0090737]; telomeric 3' overhang formation [GO:0031860] GO:0000077; GO:0000723; GO:0000724; GO:0000781; GO:0001701; GO:0001832; GO:0003684; GO:0005634; GO:0005657; GO:0005730; GO:0006302; GO:0007095; GO:0007405; GO:0008283; GO:0008284; GO:0009410; GO:0016605; GO:0030870; GO:0031860; GO:0031954; GO:0032206; GO:0032508; GO:0033674; GO:0035861; GO:0042405; GO:0045190; GO:0045665; GO:0046597; GO:0047485; GO:0048145; GO:0050885; GO:0051321; GO:0070533; GO:0090656; GO:0090737; GO:0097193; GO:0140297; GO:1904354 37942 XM_044316584.1 4 0 1 12 0 Q09575 1.57e-33 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 37943 XM_044319799.1 194 111 82 176 84 NA NA NA NA NA NA 37944 XM_029334153.2 6569 6509 2177 6048 6213 Q9HBY0 1.12e-174 NADPH oxidase 3 (EC 1.6.3.-) (Mitogenic oxidase 2) (MOX-2) (gp91phox homolog 3) (GP91-3) Homo sapiens (Human) defense response [GO:0006952]; detection of gravity [GO:0009590]; otolith development [GO:0048840]; superoxide anion generation [GO:0042554]; temperature homeostasis [GO:0001659] GO:0001659; GO:0005737; GO:0005886; GO:0006952; GO:0009590; GO:0016175; GO:0042554; GO:0043020; GO:0048840; GO:0070062 37945 XM_029349751.2 6 10 19 5 4 Q94K49 6.18e-27 Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1 (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) epigenetic regulation of gene expression [GO:0040029] GO:0003682; GO:0004518; GO:0005634; GO:0035098; GO:0035102; GO:0040029; GO:0046872 37946 XM_029332413.2 158 92 104 254 212 NA NA NA NA NA NA 37947 XM_029325271.2 308 116 0 25 0 NA NA NA NA NA NA 37948 XM_029346130.2 226 251 219 347 146 NA NA NA NA NA NA 37949 XM_029323869.2 0 11 31 0 34 NA NA NA NA NA NA 37950 XM_044308489.1 280 188 287 552 403 Q96RT1 4.57e-129 Erbin (Densin-180-like protein) (Erbb2-interacting protein) (Protein LAP2) Homo sapiens (Human) basal protein localization [GO:0045175]; cell adhesion [GO:0007155]; cellular response to tumor necrosis factor [GO:0071356]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; integrin-mediated signaling pathway [GO:0007229]; intermediate filament cytoskeleton organization [GO:0045104]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070433]; positive regulation of Ras protein signal transduction [GO:0046579]; protein targeting [GO:0006605]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; signal transduction [GO:0007165] GO:0005102; GO:0005176; GO:0005200; GO:0005604; GO:0005634; GO:0005737; GO:0005886; GO:0006605; GO:0007155; GO:0007165; GO:0007173; GO:0007229; GO:0009925; GO:0016323; GO:0016607; GO:0030054; GO:0030056; GO:0031965; GO:0032088; GO:0032495; GO:0032496; GO:0045104; GO:0045175; GO:0045197; GO:0046579; GO:0070433; GO:0071356; GO:0071638; GO:0098794; GO:0098978; GO:0099072 37951 XM_029357577.2 453 385 403 574 806 Q8BX80 1.46e-123 Cytosolic endo-beta-N-acetylglucosaminidase (ENGase) (EC 3.2.1.96) Mus musculus (Mouse) protein deglycosylation [GO:0006517] GO:0004553; GO:0005829; GO:0006517; GO:0033925 37952 XM_044307138.1 3 2 13 0 0 Q924H0 8.96e-23 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide NPFF receptor) Mus musculus (Mouse) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 37953 XM_029349867.2 3154 2075 1713 2715 3308 A9UMS3 3.52e-136 Prohibitin-2 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) mitophagy [GO:0000423] GO:0000423; GO:0005634; GO:0005737; GO:0005743; GO:0005886; GO:0009986; GO:0016363; GO:0035632; GO:0042803 37954 XR_006393908.1 41 2 25 5 151 NA NA NA NA NA NA 37955 XM_044325232.1 141 163 120 149 299 NA NA NA NA NA NA 37956 XM_044317021.1 0 0 13 0 22 P36544 2.24e-85 Neuronal acetylcholine receptor subunit alpha-7 Homo sapiens (Human) acetylcholine receptor signaling pathway [GO:0095500]; calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; cognition [GO:0050890]; dendrite arborization [GO:0140059]; dendritic spine organization [GO:0097061]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; learning or memory [GO:0007611]; membrane depolarization [GO:0051899]; memory [GO:0007613]; modulation of excitatory postsynaptic potential [GO:0098815]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of tumor necrosis factor production [GO:0032720]; nervous system process [GO:0050877]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of CoA-transferase activity [GO:1905920]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; regulation of amyloid fibril formation [GO:1905906]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of membrane potential [GO:0042391]; regulation of neuron death [GO:1901214]; regulation of nitric oxide metabolic process [GO:0080164]; response to acetylcholine [GO:1905144]; response to amyloid-beta [GO:1904645]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; sensory processing [GO:0050893]; short-term memory [GO:0007614]; signal transduction [GO:0007165]; synapse organization [GO:0050808]; synaptic transmission, cholinergic [GO:0007271] GO:0001540; GO:0001666; GO:0001934; GO:0005216; GO:0005231; GO:0005262; GO:0005886; GO:0005892; GO:0006811; GO:0006816; GO:0006874; GO:0007165; GO:0007268; GO:0007271; GO:0007611; GO:0007613; GO:0007614; GO:0008284; GO:0015464; GO:0015643; GO:0016020; GO:0017081; GO:0022848; GO:0030594; GO:0032720; GO:0034220; GO:0035094; GO:0042166; GO:0042391; GO:0042803; GO:0043005; GO:0043410; GO:0044853; GO:0045202; GO:0045211; GO:0045766; GO:0050808; GO:0050877; GO:0050890; GO:0050893; GO:0051247; GO:0051899; GO:0070374; GO:0080164; GO:0095500; GO:0097061; GO:0098794; GO:0098815; GO:0140059; GO:1900273; GO:1901214; GO:1902004; GO:1902430; GO:1902991; GO:1904315; GO:1904645; GO:1905144; GO:1905906; GO:1905920; GO:2000463 37957 XM_029327876.2 2932 1680 1261 1907 1454 Q8GW72 5.85e-31 Alpha-L-fucosidase 1 (EC 3.2.1.51) (Alpha-1,3/4-fucosidase) (AtFUC1) (Alpha-L-fucoside fucohydrolase) Arabidopsis thaliana (Mouse-ear cress) fucose metabolic process [GO:0006004]; glycoprotein catabolic process [GO:0006516]; glycoside catabolic process [GO:0016139] GO:0000325; GO:0004560; GO:0005764; GO:0006004; GO:0006516; GO:0016139; GO:0048046; GO:0099503 37958 XM_029351515.2 37 611 0 8 4 NA NA NA NA NA NA 37959 XM_044324973.1 427 240 290 356 462 Q9QW30 6.52e-132 Neurogenic locus notch homolog protein 2 (Notch 2) [Cleaved into: Notch 2 extracellular truncation; Notch 2 intracellular domain] Rattus norvegicus (Rat) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; atrial septum morphogenesis [GO:0060413]; BMP signaling pathway [GO:0030509]; bone remodeling [GO:0046849]; cell fate determination [GO:0001709]; cell population proliferation [GO:0008283]; cellular response to tumor cell [GO:0071228]; central nervous system development [GO:0007417]; cholangiocyte proliferation [GO:1990705]; ciliary body morphogenesis [GO:0061073]; defense response to bacterium [GO:0042742]; determination of left/right symmetry [GO:0007368]; embryonic limb morphogenesis [GO:0030326]; glomerular capillary formation [GO:0072104]; heart looping [GO:0001947]; hepatocyte proliferation [GO:0072574]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; intrahepatic bile duct development [GO:0035622]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; liver morphogenesis [GO:0072576]; marginal zone B cell differentiation [GO:0002315]; morphogenesis of an epithelial sheet [GO:0002011]; multicellular organism growth [GO:0035264]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; placenta blood vessel development [GO:0060674]; placenta development [GO:0001890]; podocyte development [GO:0072015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of Ras protein signal transduction [GO:0046579]; proximal tubule development [GO:0072014]; pulmonary valve morphogenesis [GO:0003184]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of osteoclast development [GO:2001204]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal system development [GO:0001501]; tissue regeneration [GO:0042246]; wound healing [GO:0042060] GO:0000122; GO:0001501; GO:0001701; GO:0001709; GO:0001889; GO:0001890; GO:0001947; GO:0002011; GO:0002315; GO:0002437; GO:0003184; GO:0005509; GO:0005576; GO:0005634; GO:0005829; GO:0005886; GO:0005929; GO:0006357; GO:0006915; GO:0006959; GO:0007219; GO:0007368; GO:0007417; GO:0008283; GO:0008284; GO:0009887; GO:0009986; GO:0010629; GO:0010838; GO:0019899; GO:0030326; GO:0030509; GO:0030513; GO:0031012; GO:0035264; GO:0035622; GO:0038023; GO:0042060; GO:0042246; GO:0042742; GO:0043011; GO:0043065; GO:0043235; GO:0045672; GO:0046579; GO:0046849; GO:0051059; GO:0060413; GO:0060674; GO:0061073; GO:0070374; GO:0070986; GO:0071228; GO:0072014; GO:0072015; GO:0072104; GO:0072574; GO:0072576; GO:1990705; GO:2000249; GO:2001204 37960 XM_044324973.1 427 240 290 356 462 Q9QW30 1.56e-128 Neurogenic locus notch homolog protein 2 (Notch 2) [Cleaved into: Notch 2 extracellular truncation; Notch 2 intracellular domain] Rattus norvegicus (Rat) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; atrial septum morphogenesis [GO:0060413]; BMP signaling pathway [GO:0030509]; bone remodeling [GO:0046849]; cell fate determination [GO:0001709]; cell population proliferation [GO:0008283]; cellular response to tumor cell [GO:0071228]; central nervous system development [GO:0007417]; cholangiocyte proliferation [GO:1990705]; ciliary body morphogenesis [GO:0061073]; defense response to bacterium [GO:0042742]; determination of left/right symmetry [GO:0007368]; embryonic limb morphogenesis [GO:0030326]; glomerular capillary formation [GO:0072104]; heart looping [GO:0001947]; hepatocyte proliferation [GO:0072574]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; intrahepatic bile duct development [GO:0035622]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; liver morphogenesis [GO:0072576]; marginal zone B cell differentiation [GO:0002315]; morphogenesis of an epithelial sheet [GO:0002011]; multicellular organism growth [GO:0035264]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; placenta blood vessel development [GO:0060674]; placenta development [GO:0001890]; podocyte development [GO:0072015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of Ras protein signal transduction [GO:0046579]; proximal tubule development [GO:0072014]; pulmonary valve morphogenesis [GO:0003184]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of osteoclast development [GO:2001204]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal system development [GO:0001501]; tissue regeneration [GO:0042246]; wound healing [GO:0042060] GO:0000122; GO:0001501; GO:0001701; GO:0001709; GO:0001889; GO:0001890; GO:0001947; GO:0002011; GO:0002315; GO:0002437; GO:0003184; GO:0005509; GO:0005576; GO:0005634; GO:0005829; GO:0005886; GO:0005929; GO:0006357; GO:0006915; GO:0006959; GO:0007219; GO:0007368; GO:0007417; GO:0008283; GO:0008284; GO:0009887; GO:0009986; GO:0010629; GO:0010838; GO:0019899; GO:0030326; GO:0030509; GO:0030513; GO:0031012; GO:0035264; GO:0035622; GO:0038023; GO:0042060; GO:0042246; GO:0042742; GO:0043011; GO:0043065; GO:0043235; GO:0045672; GO:0046579; GO:0046849; GO:0051059; GO:0060413; GO:0060674; GO:0061073; GO:0070374; GO:0070986; GO:0071228; GO:0072014; GO:0072015; GO:0072104; GO:0072574; GO:0072576; GO:1990705; GO:2000249; GO:2001204 37961 XM_044324973.1 427 240 290 356 462 Q9QW30 1.36e-127 Neurogenic locus notch homolog protein 2 (Notch 2) [Cleaved into: Notch 2 extracellular truncation; Notch 2 intracellular domain] Rattus norvegicus (Rat) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; atrial septum morphogenesis [GO:0060413]; BMP signaling pathway [GO:0030509]; bone remodeling [GO:0046849]; cell fate determination [GO:0001709]; cell population proliferation [GO:0008283]; cellular response to tumor cell [GO:0071228]; central nervous system development [GO:0007417]; cholangiocyte proliferation [GO:1990705]; ciliary body morphogenesis [GO:0061073]; defense response to bacterium [GO:0042742]; determination of left/right symmetry [GO:0007368]; embryonic limb morphogenesis [GO:0030326]; glomerular capillary formation [GO:0072104]; heart looping [GO:0001947]; hepatocyte proliferation [GO:0072574]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; intrahepatic bile duct development [GO:0035622]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; liver morphogenesis [GO:0072576]; marginal zone B cell differentiation [GO:0002315]; morphogenesis of an epithelial sheet [GO:0002011]; multicellular organism growth [GO:0035264]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; placenta blood vessel development [GO:0060674]; placenta development [GO:0001890]; podocyte development [GO:0072015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of Ras protein signal transduction [GO:0046579]; proximal tubule development [GO:0072014]; pulmonary valve morphogenesis [GO:0003184]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of osteoclast development [GO:2001204]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal system development [GO:0001501]; tissue regeneration [GO:0042246]; wound healing [GO:0042060] GO:0000122; GO:0001501; GO:0001701; GO:0001709; GO:0001889; GO:0001890; GO:0001947; GO:0002011; GO:0002315; GO:0002437; GO:0003184; GO:0005509; GO:0005576; GO:0005634; GO:0005829; GO:0005886; GO:0005929; GO:0006357; GO:0006915; GO:0006959; GO:0007219; GO:0007368; GO:0007417; GO:0008283; GO:0008284; GO:0009887; GO:0009986; GO:0010629; GO:0010838; GO:0019899; GO:0030326; GO:0030509; GO:0030513; GO:0031012; GO:0035264; GO:0035622; GO:0038023; GO:0042060; GO:0042246; GO:0042742; GO:0043011; GO:0043065; GO:0043235; GO:0045672; GO:0046579; GO:0046849; GO:0051059; GO:0060413; GO:0060674; GO:0061073; GO:0070374; GO:0070986; GO:0071228; GO:0072014; GO:0072015; GO:0072104; GO:0072574; GO:0072576; GO:1990705; GO:2000249; GO:2001204 37962 XM_044324973.1 427 240 290 356 462 Q9QW30 2.23e-127 Neurogenic locus notch homolog protein 2 (Notch 2) [Cleaved into: Notch 2 extracellular truncation; Notch 2 intracellular domain] Rattus norvegicus (Rat) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; atrial septum morphogenesis [GO:0060413]; BMP signaling pathway [GO:0030509]; bone remodeling [GO:0046849]; cell fate determination [GO:0001709]; cell population proliferation [GO:0008283]; cellular response to tumor cell [GO:0071228]; central nervous system development [GO:0007417]; cholangiocyte proliferation [GO:1990705]; ciliary body morphogenesis [GO:0061073]; defense response to bacterium [GO:0042742]; determination of left/right symmetry [GO:0007368]; embryonic limb morphogenesis [GO:0030326]; glomerular capillary formation [GO:0072104]; heart looping [GO:0001947]; hepatocyte proliferation [GO:0072574]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; intrahepatic bile duct development [GO:0035622]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; liver morphogenesis [GO:0072576]; marginal zone B cell differentiation [GO:0002315]; morphogenesis of an epithelial sheet [GO:0002011]; multicellular organism growth [GO:0035264]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; placenta blood vessel development [GO:0060674]; placenta development [GO:0001890]; podocyte development [GO:0072015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of Ras protein signal transduction [GO:0046579]; proximal tubule development [GO:0072014]; pulmonary valve morphogenesis [GO:0003184]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of osteoclast development [GO:2001204]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal system development [GO:0001501]; tissue regeneration [GO:0042246]; wound healing [GO:0042060] GO:0000122; GO:0001501; GO:0001701; GO:0001709; GO:0001889; GO:0001890; GO:0001947; GO:0002011; GO:0002315; GO:0002437; GO:0003184; GO:0005509; GO:0005576; GO:0005634; GO:0005829; GO:0005886; GO:0005929; GO:0006357; GO:0006915; GO:0006959; GO:0007219; GO:0007368; GO:0007417; GO:0008283; GO:0008284; GO:0009887; GO:0009986; GO:0010629; GO:0010838; GO:0019899; GO:0030326; GO:0030509; GO:0030513; GO:0031012; GO:0035264; GO:0035622; GO:0038023; GO:0042060; GO:0042246; GO:0042742; GO:0043011; GO:0043065; GO:0043235; GO:0045672; GO:0046579; GO:0046849; GO:0051059; GO:0060413; GO:0060674; GO:0061073; GO:0070374; GO:0070986; GO:0071228; GO:0072014; GO:0072015; GO:0072104; GO:0072574; GO:0072576; GO:1990705; GO:2000249; GO:2001204 37963 XM_044324973.1 427 240 290 356 462 Q9QW30 6.1e-126 Neurogenic locus notch homolog protein 2 (Notch 2) [Cleaved into: Notch 2 extracellular truncation; Notch 2 intracellular domain] Rattus norvegicus (Rat) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; atrial septum morphogenesis [GO:0060413]; BMP signaling pathway [GO:0030509]; bone remodeling [GO:0046849]; cell fate determination [GO:0001709]; cell population proliferation [GO:0008283]; cellular response to tumor cell [GO:0071228]; central nervous system development [GO:0007417]; cholangiocyte proliferation [GO:1990705]; ciliary body morphogenesis [GO:0061073]; defense response to bacterium [GO:0042742]; determination of left/right symmetry [GO:0007368]; embryonic limb morphogenesis [GO:0030326]; glomerular capillary formation [GO:0072104]; heart looping [GO:0001947]; hepatocyte proliferation [GO:0072574]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; intrahepatic bile duct development [GO:0035622]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; liver morphogenesis [GO:0072576]; marginal zone B cell differentiation [GO:0002315]; morphogenesis of an epithelial sheet [GO:0002011]; multicellular organism growth [GO:0035264]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; placenta blood vessel development [GO:0060674]; placenta development [GO:0001890]; podocyte development [GO:0072015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of Ras protein signal transduction [GO:0046579]; proximal tubule development [GO:0072014]; pulmonary valve morphogenesis [GO:0003184]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of osteoclast development [GO:2001204]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal system development [GO:0001501]; tissue regeneration [GO:0042246]; wound healing [GO:0042060] GO:0000122; GO:0001501; GO:0001701; GO:0001709; GO:0001889; GO:0001890; GO:0001947; GO:0002011; GO:0002315; GO:0002437; GO:0003184; GO:0005509; GO:0005576; GO:0005634; GO:0005829; GO:0005886; GO:0005929; GO:0006357; GO:0006915; GO:0006959; GO:0007219; GO:0007368; GO:0007417; GO:0008283; GO:0008284; GO:0009887; GO:0009986; GO:0010629; GO:0010838; GO:0019899; GO:0030326; GO:0030509; GO:0030513; GO:0031012; GO:0035264; GO:0035622; GO:0038023; GO:0042060; GO:0042246; GO:0042742; GO:0043011; GO:0043065; GO:0043235; GO:0045672; GO:0046579; GO:0046849; GO:0051059; GO:0060413; GO:0060674; GO:0061073; GO:0070374; GO:0070986; GO:0071228; GO:0072014; GO:0072015; GO:0072104; GO:0072574; GO:0072576; GO:1990705; GO:2000249; GO:2001204 37964 XM_044324973.1 427 240 290 356 462 Q9QW30 6.9e-117 Neurogenic locus notch homolog protein 2 (Notch 2) [Cleaved into: Notch 2 extracellular truncation; Notch 2 intracellular domain] Rattus norvegicus (Rat) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; atrial septum morphogenesis [GO:0060413]; BMP signaling pathway [GO:0030509]; bone remodeling [GO:0046849]; cell fate determination [GO:0001709]; cell population proliferation [GO:0008283]; cellular response to tumor cell [GO:0071228]; central nervous system development [GO:0007417]; cholangiocyte proliferation [GO:1990705]; ciliary body morphogenesis [GO:0061073]; defense response to bacterium [GO:0042742]; determination of left/right symmetry [GO:0007368]; embryonic limb morphogenesis [GO:0030326]; glomerular capillary formation [GO:0072104]; heart looping [GO:0001947]; hepatocyte proliferation [GO:0072574]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; intrahepatic bile duct development [GO:0035622]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; liver morphogenesis [GO:0072576]; marginal zone B cell differentiation [GO:0002315]; morphogenesis of an epithelial sheet [GO:0002011]; multicellular organism growth [GO:0035264]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; placenta blood vessel development [GO:0060674]; placenta development [GO:0001890]; podocyte development [GO:0072015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of Ras protein signal transduction [GO:0046579]; proximal tubule development [GO:0072014]; pulmonary valve morphogenesis [GO:0003184]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of osteoclast development [GO:2001204]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal system development [GO:0001501]; tissue regeneration [GO:0042246]; wound healing [GO:0042060] GO:0000122; GO:0001501; GO:0001701; GO:0001709; GO:0001889; GO:0001890; GO:0001947; GO:0002011; GO:0002315; GO:0002437; GO:0003184; GO:0005509; GO:0005576; GO:0005634; GO:0005829; GO:0005886; GO:0005929; GO:0006357; GO:0006915; GO:0006959; GO:0007219; GO:0007368; GO:0007417; GO:0008283; GO:0008284; GO:0009887; GO:0009986; GO:0010629; GO:0010838; GO:0019899; GO:0030326; GO:0030509; GO:0030513; GO:0031012; GO:0035264; GO:0035622; GO:0038023; GO:0042060; GO:0042246; GO:0042742; GO:0043011; GO:0043065; GO:0043235; GO:0045672; GO:0046579; GO:0046849; GO:0051059; GO:0060413; GO:0060674; GO:0061073; GO:0070374; GO:0070986; GO:0071228; GO:0072014; GO:0072015; GO:0072104; GO:0072574; GO:0072576; GO:1990705; GO:2000249; GO:2001204 37965 XM_044324973.1 427 240 290 356 462 Q9QW30 4.03e-112 Neurogenic locus notch homolog protein 2 (Notch 2) [Cleaved into: Notch 2 extracellular truncation; Notch 2 intracellular domain] Rattus norvegicus (Rat) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; atrial septum morphogenesis [GO:0060413]; BMP signaling pathway [GO:0030509]; bone remodeling [GO:0046849]; cell fate determination [GO:0001709]; cell population proliferation [GO:0008283]; cellular response to tumor cell [GO:0071228]; central nervous system development [GO:0007417]; cholangiocyte proliferation [GO:1990705]; ciliary body morphogenesis [GO:0061073]; defense response to bacterium [GO:0042742]; determination of left/right symmetry [GO:0007368]; embryonic limb morphogenesis [GO:0030326]; glomerular capillary formation [GO:0072104]; heart looping [GO:0001947]; hepatocyte proliferation [GO:0072574]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; intrahepatic bile duct development [GO:0035622]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; liver morphogenesis [GO:0072576]; marginal zone B cell differentiation [GO:0002315]; morphogenesis of an epithelial sheet [GO:0002011]; multicellular organism growth [GO:0035264]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; placenta blood vessel development [GO:0060674]; placenta development [GO:0001890]; podocyte development [GO:0072015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of Ras protein signal transduction [GO:0046579]; proximal tubule development [GO:0072014]; pulmonary valve morphogenesis [GO:0003184]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of osteoclast development [GO:2001204]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal system development [GO:0001501]; tissue regeneration [GO:0042246]; wound healing [GO:0042060] GO:0000122; GO:0001501; GO:0001701; GO:0001709; GO:0001889; GO:0001890; GO:0001947; GO:0002011; GO:0002315; GO:0002437; GO:0003184; GO:0005509; GO:0005576; GO:0005634; GO:0005829; GO:0005886; GO:0005929; GO:0006357; GO:0006915; GO:0006959; GO:0007219; GO:0007368; GO:0007417; GO:0008283; GO:0008284; GO:0009887; GO:0009986; GO:0010629; GO:0010838; GO:0019899; GO:0030326; GO:0030509; GO:0030513; GO:0031012; GO:0035264; GO:0035622; GO:0038023; GO:0042060; GO:0042246; GO:0042742; GO:0043011; GO:0043065; GO:0043235; GO:0045672; GO:0046579; GO:0046849; GO:0051059; GO:0060413; GO:0060674; GO:0061073; GO:0070374; GO:0070986; GO:0071228; GO:0072014; GO:0072015; GO:0072104; GO:0072574; GO:0072576; GO:1990705; GO:2000249; GO:2001204 37966 XM_044324973.1 427 240 290 356 462 Q9QW30 9.87e-82 Neurogenic locus notch homolog protein 2 (Notch 2) [Cleaved into: Notch 2 extracellular truncation; Notch 2 intracellular domain] Rattus norvegicus (Rat) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; atrial septum morphogenesis [GO:0060413]; BMP signaling pathway [GO:0030509]; bone remodeling [GO:0046849]; cell fate determination [GO:0001709]; cell population proliferation [GO:0008283]; cellular response to tumor cell [GO:0071228]; central nervous system development [GO:0007417]; cholangiocyte proliferation [GO:1990705]; ciliary body morphogenesis [GO:0061073]; defense response to bacterium [GO:0042742]; determination of left/right symmetry [GO:0007368]; embryonic limb morphogenesis [GO:0030326]; glomerular capillary formation [GO:0072104]; heart looping [GO:0001947]; hepatocyte proliferation [GO:0072574]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; intrahepatic bile duct development [GO:0035622]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; liver morphogenesis [GO:0072576]; marginal zone B cell differentiation [GO:0002315]; morphogenesis of an epithelial sheet [GO:0002011]; multicellular organism growth [GO:0035264]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; placenta blood vessel development [GO:0060674]; placenta development [GO:0001890]; podocyte development [GO:0072015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of Ras protein signal transduction [GO:0046579]; proximal tubule development [GO:0072014]; pulmonary valve morphogenesis [GO:0003184]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of osteoclast development [GO:2001204]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal system development [GO:0001501]; tissue regeneration [GO:0042246]; wound healing [GO:0042060] GO:0000122; GO:0001501; GO:0001701; GO:0001709; GO:0001889; GO:0001890; GO:0001947; GO:0002011; GO:0002315; GO:0002437; GO:0003184; GO:0005509; GO:0005576; GO:0005634; GO:0005829; GO:0005886; GO:0005929; GO:0006357; GO:0006915; GO:0006959; GO:0007219; GO:0007368; GO:0007417; GO:0008283; GO:0008284; GO:0009887; GO:0009986; GO:0010629; GO:0010838; GO:0019899; GO:0030326; GO:0030509; GO:0030513; GO:0031012; GO:0035264; GO:0035622; GO:0038023; GO:0042060; GO:0042246; GO:0042742; GO:0043011; GO:0043065; GO:0043235; GO:0045672; GO:0046579; GO:0046849; GO:0051059; GO:0060413; GO:0060674; GO:0061073; GO:0070374; GO:0070986; GO:0071228; GO:0072014; GO:0072015; GO:0072104; GO:0072574; GO:0072576; GO:1990705; GO:2000249; GO:2001204 37967 XM_044324973.1 427 240 290 356 462 Q9QW30 3.5e-80 Neurogenic locus notch homolog protein 2 (Notch 2) [Cleaved into: Notch 2 extracellular truncation; Notch 2 intracellular domain] Rattus norvegicus (Rat) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; atrial septum morphogenesis [GO:0060413]; BMP signaling pathway [GO:0030509]; bone remodeling [GO:0046849]; cell fate determination [GO:0001709]; cell population proliferation [GO:0008283]; cellular response to tumor cell [GO:0071228]; central nervous system development [GO:0007417]; cholangiocyte proliferation [GO:1990705]; ciliary body morphogenesis [GO:0061073]; defense response to bacterium [GO:0042742]; determination of left/right symmetry [GO:0007368]; embryonic limb morphogenesis [GO:0030326]; glomerular capillary formation [GO:0072104]; heart looping [GO:0001947]; hepatocyte proliferation [GO:0072574]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; intrahepatic bile duct development [GO:0035622]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; liver morphogenesis [GO:0072576]; marginal zone B cell differentiation [GO:0002315]; morphogenesis of an epithelial sheet [GO:0002011]; multicellular organism growth [GO:0035264]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; placenta blood vessel development [GO:0060674]; placenta development [GO:0001890]; podocyte development [GO:0072015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of Ras protein signal transduction [GO:0046579]; proximal tubule development [GO:0072014]; pulmonary valve morphogenesis [GO:0003184]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of osteoclast development [GO:2001204]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal system development [GO:0001501]; tissue regeneration [GO:0042246]; wound healing [GO:0042060] GO:0000122; GO:0001501; GO:0001701; GO:0001709; GO:0001889; GO:0001890; GO:0001947; GO:0002011; GO:0002315; GO:0002437; GO:0003184; GO:0005509; GO:0005576; GO:0005634; GO:0005829; GO:0005886; GO:0005929; GO:0006357; GO:0006915; GO:0006959; GO:0007219; GO:0007368; GO:0007417; GO:0008283; GO:0008284; GO:0009887; GO:0009986; GO:0010629; GO:0010838; GO:0019899; GO:0030326; GO:0030509; GO:0030513; GO:0031012; GO:0035264; GO:0035622; GO:0038023; GO:0042060; GO:0042246; GO:0042742; GO:0043011; GO:0043065; GO:0043235; GO:0045672; GO:0046579; GO:0046849; GO:0051059; GO:0060413; GO:0060674; GO:0061073; GO:0070374; GO:0070986; GO:0071228; GO:0072014; GO:0072015; GO:0072104; GO:0072574; GO:0072576; GO:1990705; GO:2000249; GO:2001204 37968 XM_044324973.1 427 240 290 356 462 Q9QW30 3.9e-79 Neurogenic locus notch homolog protein 2 (Notch 2) [Cleaved into: Notch 2 extracellular truncation; Notch 2 intracellular domain] Rattus norvegicus (Rat) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; atrial septum morphogenesis [GO:0060413]; BMP signaling pathway [GO:0030509]; bone remodeling [GO:0046849]; cell fate determination [GO:0001709]; cell population proliferation [GO:0008283]; cellular response to tumor cell [GO:0071228]; central nervous system development [GO:0007417]; cholangiocyte proliferation [GO:1990705]; ciliary body morphogenesis [GO:0061073]; defense response to bacterium [GO:0042742]; determination of left/right symmetry [GO:0007368]; embryonic limb morphogenesis [GO:0030326]; glomerular capillary formation [GO:0072104]; heart looping [GO:0001947]; hepatocyte proliferation [GO:0072574]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; intrahepatic bile duct development [GO:0035622]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; liver morphogenesis [GO:0072576]; marginal zone B cell differentiation [GO:0002315]; morphogenesis of an epithelial sheet [GO:0002011]; multicellular organism growth [GO:0035264]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; placenta blood vessel development [GO:0060674]; placenta development [GO:0001890]; podocyte development [GO:0072015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of Ras protein signal transduction [GO:0046579]; proximal tubule development [GO:0072014]; pulmonary valve morphogenesis [GO:0003184]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of osteoclast development [GO:2001204]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal system development [GO:0001501]; tissue regeneration [GO:0042246]; wound healing [GO:0042060] GO:0000122; GO:0001501; GO:0001701; GO:0001709; GO:0001889; GO:0001890; GO:0001947; GO:0002011; GO:0002315; GO:0002437; GO:0003184; GO:0005509; GO:0005576; GO:0005634; GO:0005829; GO:0005886; GO:0005929; GO:0006357; GO:0006915; GO:0006959; GO:0007219; GO:0007368; GO:0007417; GO:0008283; GO:0008284; GO:0009887; GO:0009986; GO:0010629; GO:0010838; GO:0019899; GO:0030326; GO:0030509; GO:0030513; GO:0031012; GO:0035264; GO:0035622; GO:0038023; GO:0042060; GO:0042246; GO:0042742; GO:0043011; GO:0043065; GO:0043235; GO:0045672; GO:0046579; GO:0046849; GO:0051059; GO:0060413; GO:0060674; GO:0061073; GO:0070374; GO:0070986; GO:0071228; GO:0072014; GO:0072015; GO:0072104; GO:0072574; GO:0072576; GO:1990705; GO:2000249; GO:2001204 37969 XM_044324973.1 427 240 290 356 462 Q9QW30 7.61e-76 Neurogenic locus notch homolog protein 2 (Notch 2) [Cleaved into: Notch 2 extracellular truncation; Notch 2 intracellular domain] Rattus norvegicus (Rat) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; atrial septum morphogenesis [GO:0060413]; BMP signaling pathway [GO:0030509]; bone remodeling [GO:0046849]; cell fate determination [GO:0001709]; cell population proliferation [GO:0008283]; cellular response to tumor cell [GO:0071228]; central nervous system development [GO:0007417]; cholangiocyte proliferation [GO:1990705]; ciliary body morphogenesis [GO:0061073]; defense response to bacterium [GO:0042742]; determination of left/right symmetry [GO:0007368]; embryonic limb morphogenesis [GO:0030326]; glomerular capillary formation [GO:0072104]; heart looping [GO:0001947]; hepatocyte proliferation [GO:0072574]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; intrahepatic bile duct development [GO:0035622]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; liver morphogenesis [GO:0072576]; marginal zone B cell differentiation [GO:0002315]; morphogenesis of an epithelial sheet [GO:0002011]; multicellular organism growth [GO:0035264]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; placenta blood vessel development [GO:0060674]; placenta development [GO:0001890]; podocyte development [GO:0072015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of Ras protein signal transduction [GO:0046579]; proximal tubule development [GO:0072014]; pulmonary valve morphogenesis [GO:0003184]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of osteoclast development [GO:2001204]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal system development [GO:0001501]; tissue regeneration [GO:0042246]; wound healing [GO:0042060] GO:0000122; GO:0001501; GO:0001701; GO:0001709; GO:0001889; GO:0001890; GO:0001947; GO:0002011; GO:0002315; GO:0002437; GO:0003184; GO:0005509; GO:0005576; GO:0005634; GO:0005829; GO:0005886; GO:0005929; GO:0006357; GO:0006915; GO:0006959; GO:0007219; GO:0007368; GO:0007417; GO:0008283; GO:0008284; GO:0009887; GO:0009986; GO:0010629; GO:0010838; GO:0019899; GO:0030326; GO:0030509; GO:0030513; GO:0031012; GO:0035264; GO:0035622; GO:0038023; GO:0042060; GO:0042246; GO:0042742; GO:0043011; GO:0043065; GO:0043235; GO:0045672; GO:0046579; GO:0046849; GO:0051059; GO:0060413; GO:0060674; GO:0061073; GO:0070374; GO:0070986; GO:0071228; GO:0072014; GO:0072015; GO:0072104; GO:0072574; GO:0072576; GO:1990705; GO:2000249; GO:2001204 37970 XM_044324973.1 427 240 290 356 462 Q9QW30 1.68e-74 Neurogenic locus notch homolog protein 2 (Notch 2) [Cleaved into: Notch 2 extracellular truncation; Notch 2 intracellular domain] Rattus norvegicus (Rat) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; atrial septum morphogenesis [GO:0060413]; BMP signaling pathway [GO:0030509]; bone remodeling [GO:0046849]; cell fate determination [GO:0001709]; cell population proliferation [GO:0008283]; cellular response to tumor cell [GO:0071228]; central nervous system development [GO:0007417]; cholangiocyte proliferation [GO:1990705]; ciliary body morphogenesis [GO:0061073]; defense response to bacterium [GO:0042742]; determination of left/right symmetry [GO:0007368]; embryonic limb morphogenesis [GO:0030326]; glomerular capillary formation [GO:0072104]; heart looping [GO:0001947]; hepatocyte proliferation [GO:0072574]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; intrahepatic bile duct development [GO:0035622]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; liver morphogenesis [GO:0072576]; marginal zone B cell differentiation [GO:0002315]; morphogenesis of an epithelial sheet [GO:0002011]; multicellular organism growth [GO:0035264]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; placenta blood vessel development [GO:0060674]; placenta development [GO:0001890]; podocyte development [GO:0072015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of Ras protein signal transduction [GO:0046579]; proximal tubule development [GO:0072014]; pulmonary valve morphogenesis [GO:0003184]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of osteoclast development [GO:2001204]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal system development [GO:0001501]; tissue regeneration [GO:0042246]; wound healing [GO:0042060] GO:0000122; GO:0001501; GO:0001701; GO:0001709; GO:0001889; GO:0001890; GO:0001947; GO:0002011; GO:0002315; GO:0002437; GO:0003184; GO:0005509; GO:0005576; GO:0005634; GO:0005829; GO:0005886; GO:0005929; GO:0006357; GO:0006915; GO:0006959; GO:0007219; GO:0007368; GO:0007417; GO:0008283; GO:0008284; GO:0009887; GO:0009986; GO:0010629; GO:0010838; GO:0019899; GO:0030326; GO:0030509; GO:0030513; GO:0031012; GO:0035264; GO:0035622; GO:0038023; GO:0042060; GO:0042246; GO:0042742; GO:0043011; GO:0043065; GO:0043235; GO:0045672; GO:0046579; GO:0046849; GO:0051059; GO:0060413; GO:0060674; GO:0061073; GO:0070374; GO:0070986; GO:0071228; GO:0072014; GO:0072015; GO:0072104; GO:0072574; GO:0072576; GO:1990705; GO:2000249; GO:2001204 37971 XM_044324973.1 427 240 290 356 462 Q9QW30 8.67e-70 Neurogenic locus notch homolog protein 2 (Notch 2) [Cleaved into: Notch 2 extracellular truncation; Notch 2 intracellular domain] Rattus norvegicus (Rat) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; atrial septum morphogenesis [GO:0060413]; BMP signaling pathway [GO:0030509]; bone remodeling [GO:0046849]; cell fate determination [GO:0001709]; cell population proliferation [GO:0008283]; cellular response to tumor cell [GO:0071228]; central nervous system development [GO:0007417]; cholangiocyte proliferation [GO:1990705]; ciliary body morphogenesis [GO:0061073]; defense response to bacterium [GO:0042742]; determination of left/right symmetry [GO:0007368]; embryonic limb morphogenesis [GO:0030326]; glomerular capillary formation [GO:0072104]; heart looping [GO:0001947]; hepatocyte proliferation [GO:0072574]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; intrahepatic bile duct development [GO:0035622]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; liver morphogenesis [GO:0072576]; marginal zone B cell differentiation [GO:0002315]; morphogenesis of an epithelial sheet [GO:0002011]; multicellular organism growth [GO:0035264]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; placenta blood vessel development [GO:0060674]; placenta development [GO:0001890]; podocyte development [GO:0072015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of Ras protein signal transduction [GO:0046579]; proximal tubule development [GO:0072014]; pulmonary valve morphogenesis [GO:0003184]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of osteoclast development [GO:2001204]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal system development [GO:0001501]; tissue regeneration [GO:0042246]; wound healing [GO:0042060] GO:0000122; GO:0001501; GO:0001701; GO:0001709; GO:0001889; GO:0001890; GO:0001947; GO:0002011; GO:0002315; GO:0002437; GO:0003184; GO:0005509; GO:0005576; GO:0005634; GO:0005829; GO:0005886; GO:0005929; GO:0006357; GO:0006915; GO:0006959; GO:0007219; GO:0007368; GO:0007417; GO:0008283; GO:0008284; GO:0009887; GO:0009986; GO:0010629; GO:0010838; GO:0019899; GO:0030326; GO:0030509; GO:0030513; GO:0031012; GO:0035264; GO:0035622; GO:0038023; GO:0042060; GO:0042246; GO:0042742; GO:0043011; GO:0043065; GO:0043235; GO:0045672; GO:0046579; GO:0046849; GO:0051059; GO:0060413; GO:0060674; GO:0061073; GO:0070374; GO:0070986; GO:0071228; GO:0072014; GO:0072015; GO:0072104; GO:0072574; GO:0072576; GO:1990705; GO:2000249; GO:2001204 37972 XM_044324973.1 427 240 290 356 462 Q9QW30 1e-69 Neurogenic locus notch homolog protein 2 (Notch 2) [Cleaved into: Notch 2 extracellular truncation; Notch 2 intracellular domain] Rattus norvegicus (Rat) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; atrial septum morphogenesis [GO:0060413]; BMP signaling pathway [GO:0030509]; bone remodeling [GO:0046849]; cell fate determination [GO:0001709]; cell population proliferation [GO:0008283]; cellular response to tumor cell [GO:0071228]; central nervous system development [GO:0007417]; cholangiocyte proliferation [GO:1990705]; ciliary body morphogenesis [GO:0061073]; defense response to bacterium [GO:0042742]; determination of left/right symmetry [GO:0007368]; embryonic limb morphogenesis [GO:0030326]; glomerular capillary formation [GO:0072104]; heart looping [GO:0001947]; hepatocyte proliferation [GO:0072574]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; intrahepatic bile duct development [GO:0035622]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; liver morphogenesis [GO:0072576]; marginal zone B cell differentiation [GO:0002315]; morphogenesis of an epithelial sheet [GO:0002011]; multicellular organism growth [GO:0035264]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; placenta blood vessel development [GO:0060674]; placenta development [GO:0001890]; podocyte development [GO:0072015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of Ras protein signal transduction [GO:0046579]; proximal tubule development [GO:0072014]; pulmonary valve morphogenesis [GO:0003184]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of osteoclast development [GO:2001204]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal system development [GO:0001501]; tissue regeneration [GO:0042246]; wound healing [GO:0042060] GO:0000122; GO:0001501; GO:0001701; GO:0001709; GO:0001889; GO:0001890; GO:0001947; GO:0002011; GO:0002315; GO:0002437; GO:0003184; GO:0005509; GO:0005576; GO:0005634; GO:0005829; GO:0005886; GO:0005929; GO:0006357; GO:0006915; GO:0006959; GO:0007219; GO:0007368; GO:0007417; GO:0008283; GO:0008284; GO:0009887; GO:0009986; GO:0010629; GO:0010838; GO:0019899; GO:0030326; GO:0030509; GO:0030513; GO:0031012; GO:0035264; GO:0035622; GO:0038023; GO:0042060; GO:0042246; GO:0042742; GO:0043011; GO:0043065; GO:0043235; GO:0045672; GO:0046579; GO:0046849; GO:0051059; GO:0060413; GO:0060674; GO:0061073; GO:0070374; GO:0070986; GO:0071228; GO:0072014; GO:0072015; GO:0072104; GO:0072574; GO:0072576; GO:1990705; GO:2000249; GO:2001204 37973 XM_044324973.1 427 240 290 356 462 Q9QW30 3.94e-68 Neurogenic locus notch homolog protein 2 (Notch 2) [Cleaved into: Notch 2 extracellular truncation; Notch 2 intracellular domain] Rattus norvegicus (Rat) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; atrial septum morphogenesis [GO:0060413]; BMP signaling pathway [GO:0030509]; bone remodeling [GO:0046849]; cell fate determination [GO:0001709]; cell population proliferation [GO:0008283]; cellular response to tumor cell [GO:0071228]; central nervous system development [GO:0007417]; cholangiocyte proliferation [GO:1990705]; ciliary body morphogenesis [GO:0061073]; defense response to bacterium [GO:0042742]; determination of left/right symmetry [GO:0007368]; embryonic limb morphogenesis [GO:0030326]; glomerular capillary formation [GO:0072104]; heart looping [GO:0001947]; hepatocyte proliferation [GO:0072574]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; intrahepatic bile duct development [GO:0035622]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; liver morphogenesis [GO:0072576]; marginal zone B cell differentiation [GO:0002315]; morphogenesis of an epithelial sheet [GO:0002011]; multicellular organism growth [GO:0035264]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; placenta blood vessel development [GO:0060674]; placenta development [GO:0001890]; podocyte development [GO:0072015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of Ras protein signal transduction [GO:0046579]; proximal tubule development [GO:0072014]; pulmonary valve morphogenesis [GO:0003184]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of osteoclast development [GO:2001204]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal system development [GO:0001501]; tissue regeneration [GO:0042246]; wound healing [GO:0042060] GO:0000122; GO:0001501; GO:0001701; GO:0001709; GO:0001889; GO:0001890; GO:0001947; GO:0002011; GO:0002315; GO:0002437; GO:0003184; GO:0005509; GO:0005576; GO:0005634; GO:0005829; GO:0005886; GO:0005929; GO:0006357; GO:0006915; GO:0006959; GO:0007219; GO:0007368; GO:0007417; GO:0008283; GO:0008284; GO:0009887; GO:0009986; GO:0010629; GO:0010838; GO:0019899; GO:0030326; GO:0030509; GO:0030513; GO:0031012; GO:0035264; GO:0035622; GO:0038023; GO:0042060; GO:0042246; GO:0042742; GO:0043011; GO:0043065; GO:0043235; GO:0045672; GO:0046579; GO:0046849; GO:0051059; GO:0060413; GO:0060674; GO:0061073; GO:0070374; GO:0070986; GO:0071228; GO:0072014; GO:0072015; GO:0072104; GO:0072574; GO:0072576; GO:1990705; GO:2000249; GO:2001204 37974 XM_044324973.1 427 240 290 356 462 Q9QW30 4.74e-68 Neurogenic locus notch homolog protein 2 (Notch 2) [Cleaved into: Notch 2 extracellular truncation; Notch 2 intracellular domain] Rattus norvegicus (Rat) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; atrial septum morphogenesis [GO:0060413]; BMP signaling pathway [GO:0030509]; bone remodeling [GO:0046849]; cell fate determination [GO:0001709]; cell population proliferation [GO:0008283]; cellular response to tumor cell [GO:0071228]; central nervous system development [GO:0007417]; cholangiocyte proliferation [GO:1990705]; ciliary body morphogenesis [GO:0061073]; defense response to bacterium [GO:0042742]; determination of left/right symmetry [GO:0007368]; embryonic limb morphogenesis [GO:0030326]; glomerular capillary formation [GO:0072104]; heart looping [GO:0001947]; hepatocyte proliferation [GO:0072574]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; intrahepatic bile duct development [GO:0035622]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; liver morphogenesis [GO:0072576]; marginal zone B cell differentiation [GO:0002315]; morphogenesis of an epithelial sheet [GO:0002011]; multicellular organism growth [GO:0035264]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; placenta blood vessel development [GO:0060674]; placenta development [GO:0001890]; podocyte development [GO:0072015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of Ras protein signal transduction [GO:0046579]; proximal tubule development [GO:0072014]; pulmonary valve morphogenesis [GO:0003184]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of osteoclast development [GO:2001204]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal system development [GO:0001501]; tissue regeneration [GO:0042246]; wound healing [GO:0042060] GO:0000122; GO:0001501; GO:0001701; GO:0001709; GO:0001889; GO:0001890; GO:0001947; GO:0002011; GO:0002315; GO:0002437; GO:0003184; GO:0005509; GO:0005576; GO:0005634; GO:0005829; GO:0005886; GO:0005929; GO:0006357; GO:0006915; GO:0006959; GO:0007219; GO:0007368; GO:0007417; GO:0008283; GO:0008284; GO:0009887; GO:0009986; GO:0010629; GO:0010838; GO:0019899; GO:0030326; GO:0030509; GO:0030513; GO:0031012; GO:0035264; GO:0035622; GO:0038023; GO:0042060; GO:0042246; GO:0042742; GO:0043011; GO:0043065; GO:0043235; GO:0045672; GO:0046579; GO:0046849; GO:0051059; GO:0060413; GO:0060674; GO:0061073; GO:0070374; GO:0070986; GO:0071228; GO:0072014; GO:0072015; GO:0072104; GO:0072574; GO:0072576; GO:1990705; GO:2000249; GO:2001204 37975 XM_044324973.1 427 240 290 356 462 Q9QW30 2e-61 Neurogenic locus notch homolog protein 2 (Notch 2) [Cleaved into: Notch 2 extracellular truncation; Notch 2 intracellular domain] Rattus norvegicus (Rat) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; atrial septum morphogenesis [GO:0060413]; BMP signaling pathway [GO:0030509]; bone remodeling [GO:0046849]; cell fate determination [GO:0001709]; cell population proliferation [GO:0008283]; cellular response to tumor cell [GO:0071228]; central nervous system development [GO:0007417]; cholangiocyte proliferation [GO:1990705]; ciliary body morphogenesis [GO:0061073]; defense response to bacterium [GO:0042742]; determination of left/right symmetry [GO:0007368]; embryonic limb morphogenesis [GO:0030326]; glomerular capillary formation [GO:0072104]; heart looping [GO:0001947]; hepatocyte proliferation [GO:0072574]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; intrahepatic bile duct development [GO:0035622]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; liver morphogenesis [GO:0072576]; marginal zone B cell differentiation [GO:0002315]; morphogenesis of an epithelial sheet [GO:0002011]; multicellular organism growth [GO:0035264]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; placenta blood vessel development [GO:0060674]; placenta development [GO:0001890]; podocyte development [GO:0072015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of Ras protein signal transduction [GO:0046579]; proximal tubule development [GO:0072014]; pulmonary valve morphogenesis [GO:0003184]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of osteoclast development [GO:2001204]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal system development [GO:0001501]; tissue regeneration [GO:0042246]; wound healing [GO:0042060] GO:0000122; GO:0001501; GO:0001701; GO:0001709; GO:0001889; GO:0001890; GO:0001947; GO:0002011; GO:0002315; GO:0002437; GO:0003184; GO:0005509; GO:0005576; GO:0005634; GO:0005829; GO:0005886; GO:0005929; GO:0006357; GO:0006915; GO:0006959; GO:0007219; GO:0007368; GO:0007417; GO:0008283; GO:0008284; GO:0009887; GO:0009986; GO:0010629; GO:0010838; GO:0019899; GO:0030326; GO:0030509; GO:0030513; GO:0031012; GO:0035264; GO:0035622; GO:0038023; GO:0042060; GO:0042246; GO:0042742; GO:0043011; GO:0043065; GO:0043235; GO:0045672; GO:0046579; GO:0046849; GO:0051059; GO:0060413; GO:0060674; GO:0061073; GO:0070374; GO:0070986; GO:0071228; GO:0072014; GO:0072015; GO:0072104; GO:0072574; GO:0072576; GO:1990705; GO:2000249; GO:2001204 37976 XM_044324973.1 427 240 290 356 462 Q9QW30 2.6e-56 Neurogenic locus notch homolog protein 2 (Notch 2) [Cleaved into: Notch 2 extracellular truncation; Notch 2 intracellular domain] Rattus norvegicus (Rat) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; atrial septum morphogenesis [GO:0060413]; BMP signaling pathway [GO:0030509]; bone remodeling [GO:0046849]; cell fate determination [GO:0001709]; cell population proliferation [GO:0008283]; cellular response to tumor cell [GO:0071228]; central nervous system development [GO:0007417]; cholangiocyte proliferation [GO:1990705]; ciliary body morphogenesis [GO:0061073]; defense response to bacterium [GO:0042742]; determination of left/right symmetry [GO:0007368]; embryonic limb morphogenesis [GO:0030326]; glomerular capillary formation [GO:0072104]; heart looping [GO:0001947]; hepatocyte proliferation [GO:0072574]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; intrahepatic bile duct development [GO:0035622]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; liver morphogenesis [GO:0072576]; marginal zone B cell differentiation [GO:0002315]; morphogenesis of an epithelial sheet [GO:0002011]; multicellular organism growth [GO:0035264]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; placenta blood vessel development [GO:0060674]; placenta development [GO:0001890]; podocyte development [GO:0072015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of Ras protein signal transduction [GO:0046579]; proximal tubule development [GO:0072014]; pulmonary valve morphogenesis [GO:0003184]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of osteoclast development [GO:2001204]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal system development [GO:0001501]; tissue regeneration [GO:0042246]; wound healing [GO:0042060] GO:0000122; GO:0001501; GO:0001701; GO:0001709; GO:0001889; GO:0001890; GO:0001947; GO:0002011; GO:0002315; GO:0002437; GO:0003184; GO:0005509; GO:0005576; GO:0005634; GO:0005829; GO:0005886; GO:0005929; GO:0006357; GO:0006915; GO:0006959; GO:0007219; GO:0007368; GO:0007417; GO:0008283; GO:0008284; GO:0009887; GO:0009986; GO:0010629; GO:0010838; GO:0019899; GO:0030326; GO:0030509; GO:0030513; GO:0031012; GO:0035264; GO:0035622; GO:0038023; GO:0042060; GO:0042246; GO:0042742; GO:0043011; GO:0043065; GO:0043235; GO:0045672; GO:0046579; GO:0046849; GO:0051059; GO:0060413; GO:0060674; GO:0061073; GO:0070374; GO:0070986; GO:0071228; GO:0072014; GO:0072015; GO:0072104; GO:0072574; GO:0072576; GO:1990705; GO:2000249; GO:2001204 37977 XM_044324973.1 427 240 290 356 462 Q9QW30 1.68e-39 Neurogenic locus notch homolog protein 2 (Notch 2) [Cleaved into: Notch 2 extracellular truncation; Notch 2 intracellular domain] Rattus norvegicus (Rat) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; atrial septum morphogenesis [GO:0060413]; BMP signaling pathway [GO:0030509]; bone remodeling [GO:0046849]; cell fate determination [GO:0001709]; cell population proliferation [GO:0008283]; cellular response to tumor cell [GO:0071228]; central nervous system development [GO:0007417]; cholangiocyte proliferation [GO:1990705]; ciliary body morphogenesis [GO:0061073]; defense response to bacterium [GO:0042742]; determination of left/right symmetry [GO:0007368]; embryonic limb morphogenesis [GO:0030326]; glomerular capillary formation [GO:0072104]; heart looping [GO:0001947]; hepatocyte proliferation [GO:0072574]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; intrahepatic bile duct development [GO:0035622]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; liver morphogenesis [GO:0072576]; marginal zone B cell differentiation [GO:0002315]; morphogenesis of an epithelial sheet [GO:0002011]; multicellular organism growth [GO:0035264]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; placenta blood vessel development [GO:0060674]; placenta development [GO:0001890]; podocyte development [GO:0072015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of Ras protein signal transduction [GO:0046579]; proximal tubule development [GO:0072014]; pulmonary valve morphogenesis [GO:0003184]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of osteoclast development [GO:2001204]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal system development [GO:0001501]; tissue regeneration [GO:0042246]; wound healing [GO:0042060] GO:0000122; GO:0001501; GO:0001701; GO:0001709; GO:0001889; GO:0001890; GO:0001947; GO:0002011; GO:0002315; GO:0002437; GO:0003184; GO:0005509; GO:0005576; GO:0005634; GO:0005829; GO:0005886; GO:0005929; GO:0006357; GO:0006915; GO:0006959; GO:0007219; GO:0007368; GO:0007417; GO:0008283; GO:0008284; GO:0009887; GO:0009986; GO:0010629; GO:0010838; GO:0019899; GO:0030326; GO:0030509; GO:0030513; GO:0031012; GO:0035264; GO:0035622; GO:0038023; GO:0042060; GO:0042246; GO:0042742; GO:0043011; GO:0043065; GO:0043235; GO:0045672; GO:0046579; GO:0046849; GO:0051059; GO:0060413; GO:0060674; GO:0061073; GO:0070374; GO:0070986; GO:0071228; GO:0072014; GO:0072015; GO:0072104; GO:0072574; GO:0072576; GO:1990705; GO:2000249; GO:2001204 37978 XM_044324973.1 427 240 290 356 462 Q9QW30 3.57e-32 Neurogenic locus notch homolog protein 2 (Notch 2) [Cleaved into: Notch 2 extracellular truncation; Notch 2 intracellular domain] Rattus norvegicus (Rat) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; atrial septum morphogenesis [GO:0060413]; BMP signaling pathway [GO:0030509]; bone remodeling [GO:0046849]; cell fate determination [GO:0001709]; cell population proliferation [GO:0008283]; cellular response to tumor cell [GO:0071228]; central nervous system development [GO:0007417]; cholangiocyte proliferation [GO:1990705]; ciliary body morphogenesis [GO:0061073]; defense response to bacterium [GO:0042742]; determination of left/right symmetry [GO:0007368]; embryonic limb morphogenesis [GO:0030326]; glomerular capillary formation [GO:0072104]; heart looping [GO:0001947]; hepatocyte proliferation [GO:0072574]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; intrahepatic bile duct development [GO:0035622]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; liver morphogenesis [GO:0072576]; marginal zone B cell differentiation [GO:0002315]; morphogenesis of an epithelial sheet [GO:0002011]; multicellular organism growth [GO:0035264]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; placenta blood vessel development [GO:0060674]; placenta development [GO:0001890]; podocyte development [GO:0072015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of Ras protein signal transduction [GO:0046579]; proximal tubule development [GO:0072014]; pulmonary valve morphogenesis [GO:0003184]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of osteoclast development [GO:2001204]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal system development [GO:0001501]; tissue regeneration [GO:0042246]; wound healing [GO:0042060] GO:0000122; GO:0001501; GO:0001701; GO:0001709; GO:0001889; GO:0001890; GO:0001947; GO:0002011; GO:0002315; GO:0002437; GO:0003184; GO:0005509; GO:0005576; GO:0005634; GO:0005829; GO:0005886; GO:0005929; GO:0006357; GO:0006915; GO:0006959; GO:0007219; GO:0007368; GO:0007417; GO:0008283; GO:0008284; GO:0009887; GO:0009986; GO:0010629; GO:0010838; GO:0019899; GO:0030326; GO:0030509; GO:0030513; GO:0031012; GO:0035264; GO:0035622; GO:0038023; GO:0042060; GO:0042246; GO:0042742; GO:0043011; GO:0043065; GO:0043235; GO:0045672; GO:0046579; GO:0046849; GO:0051059; GO:0060413; GO:0060674; GO:0061073; GO:0070374; GO:0070986; GO:0071228; GO:0072014; GO:0072015; GO:0072104; GO:0072574; GO:0072576; GO:1990705; GO:2000249; GO:2001204 37979 XM_029340227.2 1350 981 726 1598 1554 Q6ZWH5 0 Serine/threonine-protein kinase Nek10 (EC 2.7.11.1) (Never in mitosis A-related kinase 10) (NimA-related protein kinase 10) Homo sapiens (Human) mucociliary clearance [GO:0120197]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein autophosphorylation [GO:0031954]; protein phosphorylation [GO:0006468]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of ERK1 and ERK2 cascade [GO:0070372] GO:0004672; GO:0004674; GO:0005524; GO:0005576; GO:0006468; GO:0031954; GO:0043406; GO:0046872; GO:0070372; GO:0106310; GO:0120197; GO:1902749; GO:1902911 37980 XM_029340227.2 1350 981 726 1598 1554 Q6ZWH5 1.34e-29 Serine/threonine-protein kinase Nek10 (EC 2.7.11.1) (Never in mitosis A-related kinase 10) (NimA-related protein kinase 10) Homo sapiens (Human) mucociliary clearance [GO:0120197]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein autophosphorylation [GO:0031954]; protein phosphorylation [GO:0006468]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of ERK1 and ERK2 cascade [GO:0070372] GO:0004672; GO:0004674; GO:0005524; GO:0005576; GO:0006468; GO:0031954; GO:0043406; GO:0046872; GO:0070372; GO:0106310; GO:0120197; GO:1902749; GO:1902911 37981 XM_044308617.1 56 0 0 0 0 NA NA NA NA NA NA 37982 XR_003826842.2 328 445 37 211 611 NA NA NA NA NA NA 37983 XM_044319173.1 590 779 591 394 451 NA NA NA NA NA NA 37984 XM_029329436.2 5202 5477 3198 3974 3143 P62334 0 26S proteasome regulatory subunit 10B (26S proteasome AAA-ATPase subunit RPT4) (Proteasome 26S subunit ATPase 6) (Proteasome subunit p42) Mus musculus (Mouse) positive regulation of inclusion body assembly [GO:0090261]; positive regulation of RNA polymerase II transcription preinitiation complex assembly [GO:0045899]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0000502; GO:0005524; GO:0005634; GO:0008540; GO:0016234; GO:0016887; GO:0022624; GO:0030433; GO:0031597; GO:0036402; GO:0042802; GO:0043161; GO:0045899; GO:0090261 37985 XM_029353884.2 12639 9872 7445 9351 7991 NA NA NA NA NA NA 37986 XM_029348373.2 100 26 43 50 13 NA NA NA NA NA NA 37987 XM_029344882.2 74 104 132 148 145 Q9Z2D7 1.34e-65 Methyl-CpG-binding domain protein 4 (EC 3.2.2.-) (Methyl-CpG-binding protein MBD4) (Mismatch-specific DNA N-glycosylase) Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; DNA methylation [GO:0006306]; DNA repair [GO:0006281]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; response to radiation [GO:0009314] GO:0000785; GO:0003677; GO:0005634; GO:0005737; GO:0006281; GO:0006306; GO:0006974; GO:0007095; GO:0008263; GO:0008630; GO:0009314; GO:0016607 37988 XM_029328566.2 236 390 95 634 279 Q9YGL7 5.27e-64 Pituitary-specific positive transcription factor 1 (PIT-1) (Growth hormone factor 1) (GHF-1) Gallus gallus (Chicken) positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0045944 37989 XM_044326103.1 12 8 14 7 13 NA NA NA NA NA NA 37990 XR_006393825.1 0 241 21 31 9 NA NA NA NA NA NA 37991 XR_006396712.1 11 4 0 0 8 NA NA NA NA NA NA 37992 XR_006395803.1 131 17 40 150 41 NA NA NA NA NA NA 37993 XM_044326342.1 113 73 54 44 27 NA NA NA NA NA NA 37994 XM_029348061.2 7 3 4 0 57 NA NA NA NA NA NA 37995 XM_044310098.1 28 2 19 0 160 NA NA NA NA NA NA 37996 XM_044308621.1 14 0 0 0 0 NA NA NA NA NA NA 37997 XM_029331492.2 1080 1105 505 893 296 Q3B8R1 9.39e-78 Endoplasmic reticulum membrane-associated RNA degradation protein (ER membrane-associated RNA degradation protein) Rattus norvegicus (Rat) NA GO:0005789 37998 XM_029346039.2 0 0 0 10 0 NA NA NA NA NA NA 37999 XM_044322548.1 39 4 6 11 25 NA NA NA NA NA NA 38000 XR_003823143.2 758 399 492 273 832 NA NA NA NA NA NA 38001 XM_044321648.1 1232 791 656 884 2549 Q6IP59 3.08e-164 Choline transporter-like protein 2 (Solute carrier family 44 member 2) Xenopus laevis (African clawed frog) NA GO:0016020; GO:0022857 38002 XR_006393805.1 0 3 21 61 0 NA NA NA NA NA NA 38003 XM_029346181.2 48 0 21 0 73 P38571 6.19e-127 Lysosomal acid lipase/cholesteryl ester hydrolase (Acid cholesteryl ester hydrolase) (LAL) (EC 3.1.1.13) (Cholesteryl esterase) (Lipase A) (Sterol esterase) Homo sapiens (Human) cell morphogenesis [GO:0000902]; epithelial cell proliferation [GO:0050673]; homeostasis of number of cells within a tissue [GO:0048873]; inflammatory response [GO:0006954]; lipid catabolic process [GO:0016042]; low-density lipoprotein particle clearance [GO:0034383]; lung development [GO:0030324]; macrophage homeostasis [GO:0061519]; sterol metabolic process [GO:0016125]; tissue remodeling [GO:0048771] GO:0000902; GO:0001650; GO:0004771; GO:0005654; GO:0005764; GO:0005829; GO:0006954; GO:0016042; GO:0016125; GO:0016298; GO:0030324; GO:0034383; GO:0043202; GO:0043231; GO:0048771; GO:0048873; GO:0050673; GO:0061519 38004 XR_006394653.1 582 213 178 334 284 NA NA NA NA NA NA 38005 XM_029349261.2 29 6 26 14 36 NA NA NA NA NA NA 38006 XR_006393918.1 41 2 25 5 151 NA NA NA NA NA NA 38007 XM_029355552.2 155 110 113 95 79 NA NA NA NA NA NA 38008 XR_006394319.1 0 0 6 0 0 NA NA NA NA NA NA 38009 XM_044322888.1 1342 1672 468 1725 1484 NA NA NA NA NA NA 38010 XM_044312892.1 112 74 45 82 12 Q7TN88 7.03e-73 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 38011 XM_029324347.2 109 60 96 86 114 Q8R2T8 1.47e-97 General transcription factor 3C polypeptide 5 (TF3C-epsilon) (Transcription factor IIIC 63 kDa subunit) (TFIIIC 63 kDa subunit) (TFIIIC63) (Transcription factor IIIC subunit epsilon) Mus musculus (Mouse) skeletal muscle cell differentiation [GO:0035914]; transcription initiation at RNA polymerase III promoter [GO:0006384] GO:0000127; GO:0000995; GO:0003677; GO:0005654; GO:0006384; GO:0035914 38012 XM_044327880.1 37 37 41 62 64 P08953 6.11e-67 Protein toll Drosophila melanogaster (Fruit fly) antifungal innate immune response [GO:0061760]; cell adhesion [GO:0007155]; cell competition in a multicellular organism [GO:0035212]; defense response to Gram-positive bacterium [GO:0050830]; defense response to oomycetes [GO:0002229]; detection of virus [GO:0009597]; dorsal/ventral axis specification [GO:0009950]; heart development [GO:0007507]; innate immune response [GO:0045087]; larval somatic muscle development [GO:0007526]; negative regulation of cell growth [GO:0030308]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of multicellular organism growth [GO:0040015]; positive regulation of antifungal peptide production [GO:0002804]; positive regulation of antimicrobial peptide production [GO:0002225]; positive regulation of hemocyte proliferation [GO:0035208]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of embryonic pattern specification [GO:1902875]; response to tumor cell [GO:0002347]; response to wounding [GO:0009611]; synapse assembly [GO:0007416]; synaptic target inhibition [GO:0016201]; Toll signaling pathway [GO:0008063]; toll-like receptor signaling pathway [GO:0002224] GO:0002224; GO:0002225; GO:0002229; GO:0002347; GO:0002804; GO:0004888; GO:0004896; GO:0005769; GO:0005886; GO:0007155; GO:0007416; GO:0007507; GO:0007526; GO:0008063; GO:0009597; GO:0009611; GO:0009897; GO:0009950; GO:0009986; GO:0016201; GO:0019955; GO:0030308; GO:0032154; GO:0035208; GO:0035212; GO:0038023; GO:0040015; GO:0042802; GO:0045087; GO:0045944; GO:0046627; GO:0046790; GO:0050135; GO:0050830; GO:0061760; GO:0061809; GO:0070976; GO:1902875 38013 XR_006393676.1 19 15 97 85 11 NA NA NA NA NA NA 38014 XM_044323172.1 13 0 1 2 0 NA NA NA NA NA NA 38015 XM_044310390.1 82 281 114 122 117 NA NA NA NA NA NA 38016 XR_006395926.1 84 129 95 159 200 NA NA NA NA NA NA 38017 XM_044323797.1 549 343 184 185 103 A8QMS7 3.52e-37 Myeloid differentiation primary response protein MyD88 Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) inflammatory response [GO:0006954]; innate immune response [GO:0045087]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123] GO:0002755; GO:0005737; GO:0006954; GO:0043123; GO:0045087; GO:0070976 38018 XM_029342086.2 51 17 0 82 37 NA NA NA NA NA NA 38019 XR_003823824.2 257 2203 572 166 960 NA NA NA NA NA NA 38020 XM_044319815.1 8 0 1 0 7 NA NA NA NA NA NA 38021 XR_006398174.1 315 247 141 166 91 NA NA NA NA NA NA 38022 XM_029356415.2 1062 688 450 636 424 NA NA NA NA NA NA 38023 XM_044327202.1 31 15 37 40 33 NA NA NA NA NA NA 38024 XM_044311638.1 4 22 4 0 2 NA NA NA NA NA NA 38025 XM_029348040.2 1084 447 418 731 225 NA NA NA NA NA NA 38026 XM_044312033.1 75 0 82 3 195 P84239 7.73e-91 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 38027 XM_029349772.2 0 0 5 35 32 NA NA NA NA NA NA 38028 XM_029339183.2 239 354 112 240 143 NA NA NA NA NA NA 38029 XM_044325681.1 6 34 2 0 20 NA NA NA NA NA NA 38030 XM_029327077.2 14957 13308 8307 12789 7421 Q29RM3 3.14e-61 Receptor expression-enhancing protein 5 Bos taurus (Bovine) endoplasmic reticulum membrane organization [GO:0090158] GO:0033017; GO:0071782; GO:0090158 38031 XM_044319511.1 1462 957 636 1242 1082 A7MBL8 0 Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like 2) (Protein-kinase C-related kinase 2) Danio rerio (Zebrafish) (Brachydanio rerio) cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell division [GO:0051301]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105] GO:0004674; GO:0004698; GO:0005524; GO:0005634; GO:0005737; GO:0005856; GO:0007049; GO:0007155; GO:0018105; GO:0030027; GO:0030496; GO:0031267; GO:0032154; GO:0035556; GO:0051301; GO:0070161; GO:0106310 38032 XM_044317082.1 360 563 292 475 214 Q18969 3.64e-64 NA NA NA NA 38033 XM_044313565.1 903 687 481 887 961 P05455 4.93e-62 Lupus La protein (La autoantigen) (La ribonucleoprotein) (Sjoegren syndrome type B antigen) (SS-B) Homo sapiens (Human) histone mRNA metabolic process [GO:0008334]; IRES-dependent viral translational initiation [GO:0075522]; nuclear histone mRNA catabolic process [GO:0071045]; protein localization to cytoplasmic stress granule [GO:1903608]; tRNA 3'-end processing [GO:0042780]; tRNA 5'-leader removal [GO:0001682]; tRNA export from nucleus [GO:0006409]; tRNA modification [GO:0006400]; tRNA processing [GO:0008033] GO:0000049; GO:0000781; GO:0001682; GO:0003677; GO:0003723; GO:0003729; GO:0005634; GO:0005737; GO:0006400; GO:0006409; GO:0008033; GO:0008266; GO:0008334; GO:0042780; GO:0071045; GO:0075522; GO:1903608; GO:1990825; GO:1990904 38034 XR_006393039.1 0 6 0 0 3 NA NA NA NA NA NA 38035 XM_029336104.2 3506 2692 1309 2873 1441 NA NA NA NA NA NA 38036 XM_044314410.1 57 122 38 181 113 NA NA NA NA NA NA 38037 XR_006395620.1 25 163 52 96 39 NA NA NA NA NA NA 38038 XM_029356056.2 700 647 437 668 557 Q15428 6.55e-118 Splicing factor 3A subunit 2 (SF3a66) (Spliceosome-associated protein 62) (SAP 62) Homo sapiens (Human) mRNA 3'-splice site recognition [GO:0000389]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of neuron projection development [GO:0010976]; spliceosomal complex assembly [GO:0000245]; U2-type prespliceosome assembly [GO:1903241] GO:0000245; GO:0000389; GO:0000398; GO:0003723; GO:0005634; GO:0005654; GO:0005681; GO:0005684; GO:0005686; GO:0006397; GO:0008270; GO:0010976; GO:0016607; GO:0071004; GO:0071005; GO:0071013; GO:1903241 38039 XM_029324583.2 29 34 29 160 93 Q0IIE6 5.77e-81 ELMO domain-containing protein 1 Bos taurus (Bovine) NA GO:0005096 38040 XM_029330535.2 699 541 388 663 607 P21575 0 Dynamin-1 (EC 3.6.5.5) (B-dynamin) (D100) (Dynamin, brain) Rattus norvegicus (Rat) endocytosis [GO:0006897]; endosome organization [GO:0007032]; G protein-coupled receptor internalization [GO:0002031]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; positive regulation of synaptic vesicle recycling [GO:1903423]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of synaptic vesicle endocytosis [GO:1900242]; response to amyloid-beta [GO:1904645]; synaptic vesicle budding from presynaptic endocytic zone membrane [GO:0016185]; synaptic vesicle endocytosis [GO:0048488]; toxin transport [GO:1901998] GO:0001917; GO:0002031; GO:0003924; GO:0005525; GO:0005737; GO:0005794; GO:0005874; GO:0005886; GO:0006897; GO:0006898; GO:0007032; GO:0008017; GO:0008021; GO:0008022; GO:0016020; GO:0016185; GO:0017124; GO:0019901; GO:0030117; GO:0031623; GO:0031749; GO:0032991; GO:0042802; GO:0043196; GO:0044877; GO:0045202; GO:0048488; GO:0050804; GO:0050998; GO:0098684; GO:0098793; GO:0098835; GO:0098978; GO:0120283; GO:1900242; GO:1900244; GO:1901998; GO:1903423; GO:1904645 38041 XM_029337797.2 690 238 464 549 482 Q09299 1.34e-41 Putative RNA-binding protein EEED8.10 Caenorhabditis elegans SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0003723; GO:0019005; GO:0031146 38042 XM_044312142.1 14 0 46 5 6 NA NA NA NA NA NA 38043 XM_029328207.2 222 199 28 334 182 NA NA NA NA NA NA 38044 XM_044314261.1 228 0 91 0 0 O54781 5.51e-87 SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) (Serine/arginine-rich protein-specific kinase 2) (SR-protein-specific kinase 2) [Cleaved into: SRSF protein kinase 2 N-terminal; SRSF protein kinase 2 C-terminal] Mus musculus (Mouse) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; intracellular signal transduction [GO:0035556]; negative regulation of viral genome replication [GO:0045071]; nuclear speck organization [GO:0035063]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of viral genome replication [GO:0045070]; protein phosphorylation [GO:0006468]; R-loop processing [GO:0062176]; regulation of mRNA processing [GO:0050684]; RNA splicing [GO:0008380]; spliceosomal complex assembly [GO:0000245] GO:0000245; GO:0000287; GO:0000785; GO:0001525; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0006468; GO:0008284; GO:0008380; GO:0010628; GO:0016607; GO:0018105; GO:0030154; GO:0035063; GO:0035556; GO:0043525; GO:0045070; GO:0045071; GO:0045787; GO:0050684; GO:0062176; GO:0071889; GO:0106310 38045 XM_044314261.1 228 0 91 0 0 O54781 3.03e-82 SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) (Serine/arginine-rich protein-specific kinase 2) (SR-protein-specific kinase 2) [Cleaved into: SRSF protein kinase 2 N-terminal; SRSF protein kinase 2 C-terminal] Mus musculus (Mouse) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; intracellular signal transduction [GO:0035556]; negative regulation of viral genome replication [GO:0045071]; nuclear speck organization [GO:0035063]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of viral genome replication [GO:0045070]; protein phosphorylation [GO:0006468]; R-loop processing [GO:0062176]; regulation of mRNA processing [GO:0050684]; RNA splicing [GO:0008380]; spliceosomal complex assembly [GO:0000245] GO:0000245; GO:0000287; GO:0000785; GO:0001525; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0006468; GO:0008284; GO:0008380; GO:0010628; GO:0016607; GO:0018105; GO:0030154; GO:0035063; GO:0035556; GO:0043525; GO:0045070; GO:0045071; GO:0045787; GO:0050684; GO:0062176; GO:0071889; GO:0106310 38046 XM_044307552.1 169 27 289 486 372 Q8K596 4.56e-73 Sodium/calcium exchanger 2 (Na(+)/Ca(2+)-exchange protein 2) (Solute carrier family 8 member 2) Mus musculus (Mouse) calcium ion export across plasma membrane [GO:1990034]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport into cytosol [GO:0060402]; cell communication [GO:0007154]; cellular calcium ion homeostasis [GO:0006874]; cognition [GO:0050890]; learning [GO:0007612]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; metal ion transport [GO:0030001]; modulation of excitatory postsynaptic potential [GO:0098815]; neuron cellular homeostasis [GO:0070050]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; regulation of action potential firing pattern [GO:0099608]; regulation of calcineurin-mediated signaling [GO:0106056]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; response to ischemia [GO:0002931]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814]; synapse organization [GO:0050808] GO:0002931; GO:0005432; GO:0005516; GO:0005739; GO:0005874; GO:0005886; GO:0006814; GO:0006874; GO:0007154; GO:0007611; GO:0007612; GO:0007613; GO:0010468; GO:0014069; GO:0015081; GO:0015085; GO:0016020; GO:0016323; GO:0030001; GO:0030424; GO:0030425; GO:0035725; GO:0042383; GO:0042995; GO:0043025; GO:0043197; GO:0043679; GO:0045202; GO:0045211; GO:0046872; GO:0048172; GO:0050808; GO:0050890; GO:0051480; GO:0060291; GO:0060402; GO:0070050; GO:0070588; GO:0071902; GO:0098703; GO:0098793; GO:0098794; GO:0098815; GO:0099608; GO:0106056; GO:1905060; GO:1990034 38047 XM_044307552.1 169 27 289 486 372 Q8K596 1.18e-43 Sodium/calcium exchanger 2 (Na(+)/Ca(2+)-exchange protein 2) (Solute carrier family 8 member 2) Mus musculus (Mouse) calcium ion export across plasma membrane [GO:1990034]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport into cytosol [GO:0060402]; cell communication [GO:0007154]; cellular calcium ion homeostasis [GO:0006874]; cognition [GO:0050890]; learning [GO:0007612]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; metal ion transport [GO:0030001]; modulation of excitatory postsynaptic potential [GO:0098815]; neuron cellular homeostasis [GO:0070050]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; regulation of action potential firing pattern [GO:0099608]; regulation of calcineurin-mediated signaling [GO:0106056]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; response to ischemia [GO:0002931]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814]; synapse organization [GO:0050808] GO:0002931; GO:0005432; GO:0005516; GO:0005739; GO:0005874; GO:0005886; GO:0006814; GO:0006874; GO:0007154; GO:0007611; GO:0007612; GO:0007613; GO:0010468; GO:0014069; GO:0015081; GO:0015085; GO:0016020; GO:0016323; GO:0030001; GO:0030424; GO:0030425; GO:0035725; GO:0042383; GO:0042995; GO:0043025; GO:0043197; GO:0043679; GO:0045202; GO:0045211; GO:0046872; GO:0048172; GO:0050808; GO:0050890; GO:0051480; GO:0060291; GO:0060402; GO:0070050; GO:0070588; GO:0071902; GO:0098703; GO:0098793; GO:0098794; GO:0098815; GO:0099608; GO:0106056; GO:1905060; GO:1990034 38048 XM_029346847.2 3366 1554 778 3871 1473 P42678 1.83e-40 Eukaryotic translation initiation factor eIF1 (Protein translation factor SUI1 homolog) Anopheles gambiae (African malaria mosquito) NA GO:0003723; GO:0003743; GO:0016282; GO:0043024 38049 XM_029335951.2 487 369 183 316 474 A7RUD5 0 Cytosolic Fe-S cluster assembly factor NUBP1 homolog Nematostella vectensis (Starlet sea anemone) iron-sulfur cluster assembly [GO:0016226] GO:0005524; GO:0005829; GO:0016226; GO:0046872; GO:0051536; GO:0051539; GO:0140663 38050 XM_029348391.2 0 0 87 0 0 Q9JJS6 8.41e-106 Beta,beta-carotene 15,15'-dioxygenase (EC 1.13.11.63) (Beta-carotene dioxygenase 1) (Beta-carotene oxygenase 1) Mus musculus (Mouse) beta-carotene metabolic process [GO:1901810]; carotene catabolic process [GO:0016121]; retinal metabolic process [GO:0042574]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572] GO:0001523; GO:0003834; GO:0005829; GO:0010436; GO:0016121; GO:0042572; GO:0042574; GO:0046872; GO:1901810 38051 XM_044318197.1 738 477 0 673 721 NA NA NA NA NA NA 38052 XM_044326562.1 70 51 90 74 186 Q96AY4 6.67e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38053 XM_044326562.1 70 51 90 74 186 Q96AY4 8.45e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38054 XM_044326562.1 70 51 90 74 186 Q96AY4 9.36e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38055 XM_044326562.1 70 51 90 74 186 Q96AY4 6.8e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38056 XM_044326562.1 70 51 90 74 186 Q96AY4 9.64e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38057 XM_044326562.1 70 51 90 74 186 Q96AY4 2.09e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38058 XM_044328680.1 0 0 0 0 26 NA NA NA NA NA NA 38059 XM_044321676.1 34 0 30 0 14 Q8K3Z0 1.3e-33 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 38060 XM_044324067.1 31 0 0 0 9 Q3KPR5 7.55e-82 Basic immunoglobulin-like variable motif-containing protein Xenopus laevis (African clawed frog) NA GO:0005634; GO:0005737 38061 XM_029340306.2 657 0 98 256 155 Q15434 2.66e-80 RNA-binding motif, single-stranded-interacting protein 2 (Suppressor of CDC2 with RNA-binding motif 3) Homo sapiens (Human) RNA processing [GO:0006396] GO:0003723; GO:0003730; GO:0005634; GO:0005829; GO:0006396; GO:0008143; GO:0008266; GO:1990904 38062 XR_006391581.1 175 0 107 125 330 NA NA NA NA NA NA 38063 XM_044318347.1 2 0 0 10 0 NA NA NA NA NA NA 38064 XM_044307355.1 19 0 0 0 0 NA NA NA NA NA NA 38065 XM_044326262.1 27 16 45 10 252 NA NA NA NA NA NA 38066 XM_044307424.1 106 17 0 0 0 NA NA NA NA NA NA 38067 XM_029354563.2 81 8 14 79 34 NA NA NA NA NA NA 38068 XM_044328496.1 69 0 0 0 0 NA NA NA NA NA NA 38069 XM_044322359.1 3 0 4 3 15 Q7TN88 1.13e-54 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 38070 XM_044322359.1 3 0 4 3 15 Q7TN88 1.02e-51 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 38071 XR_006396222.1 0 0 0 20 0 Q80UG8 0 Tubulin monoglutamylase TTLL4 (EC 6.3.2.-) (Protein monoglutamylase TTLL4) (Tubulin--tyrosine ligase-like protein 4) Mus musculus (Mouse) microtubule cytoskeleton organization [GO:0000226]; peptidyl-glutamic acid modification [GO:0018200]; protein polyglutamylation [GO:0018095]; regulation of blastocyst development [GO:0120222] GO:0000226; GO:0005524; GO:0005737; GO:0005874; GO:0005929; GO:0015631; GO:0018095; GO:0018200; GO:0036064; GO:0046872; GO:0070739; GO:0070740; GO:0097731; GO:0120222 38072 XM_044309552.1 37 32 47 39 96 NA NA NA NA NA NA 38073 XM_029331585.2 95 96 68 112 325 NA NA NA NA NA NA 38074 XM_044328345.1 15 0 0 0 79 NA NA NA NA NA NA 38075 XM_044315466.1 46 49 59 58 25 O43422 2.06e-75 52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (Death-associated protein 4) (THAP domain-containing protein 0) (THAP domain-containing protein 12) Homo sapiens (Human) negative regulation of cell population proliferation [GO:0008285]; signal transduction [GO:0007165] GO:0003677; GO:0005634; GO:0007165; GO:0008285; GO:0046872; GO:0046983 38076 XR_006394751.1 17 3 15 21 42 NA NA NA NA NA NA 38077 XM_029346788.2 713 12 18 757 14 NA NA NA NA NA NA 38078 XR_006393128.1 93 265 188 41 117 NA NA NA NA NA NA 38079 XR_006393962.1 2 36 2 0 11 NA NA NA NA NA NA 38080 XR_003825438.2 25 0 25 1 35 NA NA NA NA NA NA 38081 XM_044307512.1 254 170 159 333 203 Q6ZWH5 0 Serine/threonine-protein kinase Nek10 (EC 2.7.11.1) (Never in mitosis A-related kinase 10) (NimA-related protein kinase 10) Homo sapiens (Human) mucociliary clearance [GO:0120197]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein autophosphorylation [GO:0031954]; protein phosphorylation [GO:0006468]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of ERK1 and ERK2 cascade [GO:0070372] GO:0004672; GO:0004674; GO:0005524; GO:0005576; GO:0006468; GO:0031954; GO:0043406; GO:0046872; GO:0070372; GO:0106310; GO:0120197; GO:1902749; GO:1902911 38082 XM_044307512.1 254 170 159 333 203 Q6ZWH5 2.52e-30 Serine/threonine-protein kinase Nek10 (EC 2.7.11.1) (Never in mitosis A-related kinase 10) (NimA-related protein kinase 10) Homo sapiens (Human) mucociliary clearance [GO:0120197]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein autophosphorylation [GO:0031954]; protein phosphorylation [GO:0006468]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of ERK1 and ERK2 cascade [GO:0070372] GO:0004672; GO:0004674; GO:0005524; GO:0005576; GO:0006468; GO:0031954; GO:0043406; GO:0046872; GO:0070372; GO:0106310; GO:0120197; GO:1902749; GO:1902911 38083 XM_029340343.2 0 0 0 0 14 NA NA NA NA NA NA 38084 XR_006395347.1 18 0 8 0 11 NA NA NA NA NA NA 38085 XR_003824980.2 17 17 4 23 43 NA NA NA NA NA NA 38086 XM_044328620.1 197 146 63 315 213 Q91ZV2 5.56e-23 Discoidin, CUB and LCCL domain-containing protein 2 (Endothelial and smooth muscle cell-derived neuropilin-like protein) Rattus norvegicus (Rat) negative regulation of cell growth [GO:0030308]; wound healing [GO:0042060] GO:0005886; GO:0009986; GO:0030308; GO:0038023; GO:0042060 38087 XM_044308614.1 33 0 33 36 157 NA NA NA NA NA NA 38088 XM_044307207.1 1896 1243 961 999 902 NA NA NA NA NA NA 38089 XM_029340404.2 2471 2266 1303 1116 927 Q5ZKN1 8.15e-161 Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 9) Gallus gallus (Chicken) positive regulation of protein localization to chromatin [GO:0120187]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; protein phosphorylation [GO:0006468]; transcription by RNA polymerase II [GO:0006366] GO:0004674; GO:0004693; GO:0005524; GO:0005634; GO:0006366; GO:0006468; GO:0008353; GO:0016592; GO:0032968; GO:0045944; GO:0070691; GO:0106310; GO:0120187 38090 XM_044317229.1 3 2 38 10 20 Q94887 1.27e-32 Neurexin-4 (Neurexin IV) Drosophila melanogaster (Fruit fly) axon ensheathment [GO:0008366]; cell adhesion involved in heart morphogenesis [GO:0061343]; cell-cell junction organization [GO:0045216]; dorsal closure [GO:0007391]; establishment of glial blood-brain barrier [GO:0060857]; heart process [GO:0003015]; nerve maturation [GO:0021682]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]; synaptic target recognition [GO:0008039]; terminal button organization [GO:0072553] GO:0003015; GO:0005886; GO:0005919; GO:0007391; GO:0008039; GO:0008104; GO:0008366; GO:0019991; GO:0021682; GO:0035151; GO:0045202; GO:0045216; GO:0048786; GO:0060857; GO:0061343; GO:0072553; GO:0097105 38091 XR_006392723.1 22 0 10 2 59 NA NA NA NA NA NA 38092 XM_029330135.2 542 839 317 783 546 Q8VHR5 3.28e-33 Transcriptional repressor p66-beta (GATA zinc finger domain-containing protein 2B) (p66/p68) Mus musculus (Mouse) chromatin remodeling [GO:0006338]; histone deacetylation [GO:0016575]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of cell fate specification [GO:0042659]; regulation of stem cell differentiation [GO:2000736] GO:0000122; GO:0000781; GO:0005634; GO:0005654; GO:0006338; GO:0008270; GO:0016575; GO:0016581; GO:0016607; GO:0042659; GO:0043565; GO:0045892; GO:0045893; GO:2000736 38093 XM_044326784.1 52 32 60 22 26 NA NA NA NA NA NA 38094 XR_006392681.1 4 1 11 8 4 NA NA NA NA NA NA 38095 XM_044327201.1 0 24 0 37 20 NA NA NA NA NA NA 38096 XM_044326266.1 58 12 0 34 24 A0JPI9 1.25e-73 Leucine-rich repeat-containing protein 74A (Leucine-rich repeat-containing protein 74) Rattus norvegicus (Rat) NA NA 38097 XR_003828236.2 1166 896 480 1086 243 NA NA NA NA NA NA 38098 XR_006396109.1 1009 466 434 3085 1387 NA NA NA NA NA NA 38099 XR_003827536.2 425 304 197 848 350 NA NA NA NA NA NA 38100 XM_044319362.1 1 15 1 2 12 NA NA NA NA NA NA 38101 XM_029356347.2 1139 1371 499 439 284 Q0P5B3 3.19e-43 Rhombotin-1 (LIM domain only protein 1) (LMO-1) Bos taurus (Bovine) positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0003713; GO:0005634; GO:0045944; GO:0046872; GO:0140297 38102 XM_044313894.1 155 17 41 221 32 NA NA NA NA NA NA 38103 XM_044323526.1 24 36 26 60 45 NA NA NA NA NA NA 38104 XM_044310306.1 7 2 1 0 6 NA NA NA NA NA NA 38105 XR_003824813.2 13 0 0 5 20 NA NA NA NA NA NA 38106 XM_044322243.1 2900 2307 1623 2673 1019 P46939 2.6e-70 Utrophin (Dystrophin-related protein 1) (DRP-1) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; muscle contraction [GO:0006936]; muscle organ development [GO:0007517]; positive regulation of cell-matrix adhesion [GO:0001954]; regulation of sodium ion transmembrane transporter activity [GO:2000649] GO:0001954; GO:0003779; GO:0005178; GO:0005654; GO:0005737; GO:0005856; GO:0005886; GO:0006936; GO:0007517; GO:0008270; GO:0016010; GO:0016020; GO:0017166; GO:0019901; GO:0030036; GO:0030054; GO:0030175; GO:0030864; GO:0031527; GO:0031594; GO:0032991; GO:0042383; GO:0042995; GO:0045211; GO:0051015; GO:0070062; GO:2000649 38107 XM_044318069.1 1069 1405 1378 1799 917 NA NA NA NA NA NA 38108 XM_029339276.2 0 4 5 0 14 NA NA NA NA NA NA 38109 XM_044322936.1 157 164 159 192 203 Q8N0W4 1.2e-89 Neuroligin-4, X-linked (Neuroligin X) (HNLX) Homo sapiens (Human) adult behavior [GO:0030534]; brainstem development [GO:0003360]; cell-cell junction organization [GO:0045216]; cerebellum development [GO:0021549]; chemical synaptic transmission [GO:0007268]; learning [GO:0007612]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of excitatory postsynaptic potential [GO:0090394]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; organ growth [GO:0035265]; postsynaptic membrane assembly [GO:0097104]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; social behavior [GO:0035176]; synapse organization [GO:0050808]; synaptic vesicle endocytosis [GO:0048488]; vocalization behavior [GO:0071625] GO:0003360; GO:0005886; GO:0007158; GO:0007268; GO:0007612; GO:0009986; GO:0016020; GO:0021549; GO:0030182; GO:0030425; GO:0030534; GO:0031404; GO:0035176; GO:0035265; GO:0038023; GO:0042043; GO:0042803; GO:0045202; GO:0045216; GO:0048488; GO:0050804; GO:0050808; GO:0050839; GO:0060076; GO:0071625; GO:0090394; GO:0097104; GO:0097105; GO:0097110; GO:0098793; GO:0098839; GO:0098983; GO:0098985; GO:0099054; GO:0099634 38110 XM_029343447.2 28 29 13 0 4 NA NA NA NA NA NA 38111 XM_044307032.1 176 216 84 135 146 NA NA NA NA NA NA 38112 XM_044309612.1 102 0 0 235 0 NA NA NA NA NA NA 38113 XM_044319714.1 2 0 0 7 0 NA NA NA NA NA NA 38114 XM_044328343.1 111 69 65 108 139 NA NA NA NA NA NA 38115 XM_029347133.2 526 427 553 237 672 Q9Z0J4 0 Nitric oxide synthase, brain (EC 1.14.13.39) (Constitutive NOS) (NC-NOS) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Peptidyl-cysteine S-nitrosylase NOS1) (bNOS) Mus musculus (Mouse) arginine catabolic process [GO:0006527]; behavioral response to cocaine [GO:0048148]; calcium ion transport [GO:0006816]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to growth factor stimulus [GO:0071363]; cellular response to mechanical stimulus [GO:0071260]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; multicellular organismal response to stress [GO:0033555]; muscle contraction [GO:0006936]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood pressure [GO:0045776]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of heart contraction [GO:0045822]; negative regulation of hepatic stellate cell contraction [GO:0061875]; negative regulation of hydrolase activity [GO:0051346]; negative regulation of insulin secretion [GO:0046676]; negative regulation of iron ion transmembrane transport [GO:0034760]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of potassium ion transport [GO:0043267]; negative regulation of serotonin uptake [GO:0051612]; negative regulation of vasoconstriction [GO:0045906]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process [GO:0140196]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of histone acetylation [GO:0035066]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neuron death [GO:1901216]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of sodium ion transmembrane transport [GO:1902307]; positive regulation of the force of heart contraction [GO:0098735]; positive regulation of transcription by RNA polymerase II [GO:0045944]; potassium ion transport [GO:0006813]; regulation of heart contraction [GO:0008016]; regulation of neurogenesis [GO:0050767]; regulation of postsynaptic membrane potential [GO:0060078]; regulation of sensory perception of pain [GO:0051930]; regulation of sodium ion transport [GO:0002028]; response to estrogen [GO:0043627]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to lipopolysaccharide [GO:0032496]; response to peptide hormone [GO:0043434]; retrograde trans-synaptic signaling by nitric oxide [GO:0098924]; striated muscle contraction [GO:0006941]; synaptic signaling by nitric oxide [GO:0099163]; vasodilation [GO:0042311]; xenobiotic catabolic process [GO:0042178] GO:0001917; GO:0002028; GO:0004517; GO:0005516; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005741; GO:0005829; GO:0005856; GO:0005886; GO:0006527; GO:0006809; GO:0006813; GO:0006816; GO:0006936; GO:0006941; GO:0007263; GO:0008016; GO:0008270; GO:0008285; GO:0009408; GO:0009725; GO:0010181; GO:0012506; GO:0014069; GO:0016020; GO:0016491; GO:0016529; GO:0017080; GO:0018119; GO:0019899; GO:0020037; GO:0030018; GO:0030141; GO:0030315; GO:0030425; GO:0031284; GO:0031965; GO:0032496; GO:0032991; GO:0033017; GO:0033137; GO:0033138; GO:0033555; GO:0034760; GO:0035066; GO:0042178; GO:0042311; GO:0042383; GO:0042582; GO:0042802; GO:0043066; GO:0043197; GO:0043267; GO:0043434; GO:0043524; GO:0043627; GO:0044305; GO:0044325; GO:0045121; GO:0045184; GO:0045202; GO:0045776; GO:0045822; GO:0045893; GO:0045906; GO:0045944; GO:0046676; GO:0046870; GO:0048148; GO:0048306; GO:0048471; GO:0050660; GO:0050661; GO:0050767; GO:0051117; GO:0051219; GO:0051346; GO:0051481; GO:0051612; GO:0051649; GO:0051926; GO:0051930; GO:0060078; GO:0061875; GO:0070402; GO:0071260; GO:0071363; GO:0071872; GO:0071944; GO:0097110; GO:0098735; GO:0098924; GO:0098978; GO:0099091; GO:0099092; GO:0099163; GO:0140196; GO:1900273; GO:1901216; GO:1902307 38116 XM_044312951.1 29 51 47 279 52 Q8K3Z0 3.83e-32 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 38117 XM_044321087.1 624 448 605 1827 1091 Q17RW2 2.02e-34 Collagen alpha-1(XXIV) chain Homo sapiens (Human) extracellular matrix organization [GO:0030198] GO:0005201; GO:0005576; GO:0005581; GO:0005615; GO:0005788; GO:0030198; GO:0031012; GO:0062023 38118 XR_006391850.1 0 0 8 2 0 NA NA NA NA NA NA 38119 XM_029336668.2 65 216 155 220 229 Q0KHY3 4.29e-52 Protein mesh Drosophila melanogaster (Fruit fly) cell-matrix adhesion [GO:0007160]; smooth septate junction assembly [GO:0090528] GO:0005615; GO:0005920; GO:0007160; GO:0016327; GO:0090528 38120 XM_029335178.2 41 0 0 52 0 E1BY51 3.01e-46 Transmembrane protein 17 Gallus gallus (Chicken) cilium assembly [GO:0060271]; non-motile cilium assembly [GO:1905515]; smoothened signaling pathway [GO:0007224] GO:0007224; GO:0035869; GO:0036038; GO:0060170; GO:0060271; GO:1905515 38121 XM_029336112.2 709 746 512 819 1133 NA NA NA NA NA NA 38122 XM_044327114.1 1 13 5 11 1 NA NA NA NA NA NA 38123 XR_006393453.1 585 359 699 412 739 NA NA NA NA NA NA 38124 XM_044309600.1 11 1 6 6 0 NA NA NA NA NA NA 38125 XR_006392393.1 0 0 10 0 1 NA NA NA NA NA NA 38126 XM_029343789.2 0 13 13 0 24 NA NA NA NA NA NA 38127 XM_044319343.1 0 0 0 0 78 Q6PHS6 0 Sorting nexin-13 Mus musculus (Mouse) intracellular protein transport [GO:0006886]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547] GO:0005769; GO:0006886; GO:0009968; GO:0031901; GO:0032266; GO:0035091; GO:0043231; GO:0043547 38128 XM_029333663.2 3436 3238 1978 3442 2848 NA NA NA NA NA NA 38129 XM_029350737.2 9152 9858 9495 12724 11379 NA NA NA NA NA NA 38130 XM_044326505.1 300 149 198 200 275 Q9Y6A2 3.81e-91 Cholesterol 24-hydroxylase (CH24H) (EC 1.14.14.25) (Cholesterol 24-monooxygenase) (Cholesterol 24S-hydroxylase) (Cytochrome P450 46A1) Homo sapiens (Human) bile acid biosynthetic process [GO:0006699]; cholesterol catabolic process [GO:0006707]; nervous system development [GO:0007399]; progesterone metabolic process [GO:0042448]; protein localization to membrane raft [GO:1903044]; regulation of long-term synaptic potentiation [GO:1900271]; sterol metabolic process [GO:0016125]; xenobiotic metabolic process [GO:0006805] GO:0005506; GO:0005783; GO:0005789; GO:0006699; GO:0006707; GO:0006805; GO:0007399; GO:0008395; GO:0016125; GO:0020037; GO:0030425; GO:0033781; GO:0042448; GO:0062184; GO:0098793; GO:0098794; GO:1900271; GO:1903044 38131 XR_006397252.1 127 114 53 58 39 NA NA NA NA NA NA 38132 XM_044320091.1 2805 1127 974 1742 2751 F1NWE3 1.99e-164 Receptor-type tyrosine-protein phosphatase S (R-PTP-S) (EC 3.1.3.48) (Chick receptor tyrosine phosphatase alpha) (CRYP alpha) (CRYPalpha) Gallus gallus (Chicken) negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; synaptic membrane adhesion [GO:0099560] GO:0004725; GO:0005886; GO:0006470; GO:0008201; GO:0030424; GO:0030426; GO:0030517; GO:0030672; GO:0035335; GO:0042803; GO:0043204; GO:0043395; GO:0048671; GO:0048681; GO:0061000; GO:0098839; GO:0099560 38133 XM_044317855.1 62 104 4 17 35 NA NA NA NA NA NA 38134 XM_044313761.1 0 12 7 30 9 NA NA NA NA NA NA 38135 XM_044315775.1 8 25 29 1 27 NA NA NA NA NA NA 38136 XR_006396470.1 107 22 78 54 292 NA NA NA NA NA NA 38137 XM_029324109.2 1212 879 545 1237 1148 Q3U1T9 6.63e-125 DENN domain-containing protein 1B (Connecdenn 2) Mus musculus (Mouse) endocytic recycling [GO:0032456]; endocytosis [GO:0006897]; positive regulation of GTPase activity [GO:0043547]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; protein transport [GO:0015031]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852] GO:0005085; GO:0005829; GO:0006897; GO:0015031; GO:0016607; GO:0030136; GO:0031267; GO:0032456; GO:0043231; GO:0043547; GO:0050776; GO:0050852; GO:1901981; GO:2000553 38138 XR_006392143.1 0 2 13 0 11 NA NA NA NA NA NA 38139 XM_044316710.1 6 0 0 8 0 NA NA NA NA NA NA 38140 XM_029328281.2 548 599 257 200 998 A2A259 7.07e-42 Polycystic kidney disease 2-like 1 protein (Polycystin-2 homolog) Mus musculus (Mouse) cation transport [GO:0006812]; cellular response to acidic pH [GO:0071468]; cellular response to pH [GO:0071467]; detection of chemical stimulus involved in sensory perception of sour taste [GO:0001581]; detection of chemical stimulus involved in sensory perception of taste [GO:0050912]; detection of mechanical stimulus [GO:0050982]; inorganic cation transmembrane transport [GO:0098662]; potassium ion transmembrane transport [GO:0071805]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; response to water [GO:0009415]; sensory perception of sour taste [GO:0050915]; smoothened signaling pathway [GO:0007224]; sodium ion transmembrane transport [GO:0035725] GO:0001581; GO:0005227; GO:0005261; GO:0005262; GO:0005272; GO:0005509; GO:0005783; GO:0005829; GO:0005886; GO:0006812; GO:0007224; GO:0008092; GO:0009415; GO:0015269; GO:0015629; GO:0016020; GO:0031410; GO:0034703; GO:0034704; GO:0035725; GO:0042802; GO:0043231; GO:0043235; GO:0050912; GO:0050915; GO:0050982; GO:0051262; GO:0051289; GO:0051371; GO:0051393; GO:0060170; GO:0071467; GO:0071468; GO:0071805; GO:0097730; GO:0098662 38141 XM_044307509.1 698 449 451 610 589 Q6NRY2 0 Nucleolar protein 6 Xenopus laevis (African clawed frog) NA GO:0003723; GO:0005730 38142 XR_006397225.1 60 14 19 17 70 NA NA NA NA NA NA 38143 XM_044321405.1 2 0 4 23 20 NA NA NA NA NA NA 38144 XM_029331575.2 260 0 195 600 380 Q5RAM2 3.37e-58 Estrogen-related receptor gamma (Estrogen receptor-related protein 3) (Nuclear receptor subfamily 3 group B member 3) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) regulation of DNA-templated transcription [GO:0006355]; retinoic acid receptor signaling pathway [GO:0048384] GO:0003707; GO:0004879; GO:0005496; GO:0005654; GO:0006355; GO:0008270; GO:0043565; GO:0048384 38145 XM_044312270.1 26 0 344 46 0 NA NA NA NA NA NA 38146 XM_044318849.1 6168 7647 2594 10623 9279 P9WKB8 2.53e-25 Putative diacyglycerol O-acyltransferase MT1809 (EC 2.3.1.20) (Putative triacylglycerol synthase MT1809) Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) glycerol metabolic process [GO:0006071]; triglyceride biosynthetic process [GO:0019432] GO:0004144; GO:0006071; GO:0019432 38147 XM_029356164.2 205 70 46 76 69 Q8VCR7 8.86e-39 Putative protein-lysine deacylase ABHD14B (EC 2.3.1.-) (Alpha/beta hydrolase domain-containing protein 14B) (Abhydrolase domain-containing protein 14B) Mus musculus (Mouse) positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0016746; GO:0016787; GO:0045944 38148 XR_003823913.2 0 0 10 10 56 Q8BLA8 4.48e-27 Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Wasabi receptor) Mus musculus (Mouse) calcium ion transmembrane import into cytosol [GO:0097553]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cell surface receptor signaling pathway [GO:0007166]; cellular calcium ion homeostasis [GO:0006874]; cellular response to carbon dioxide [GO:0071244]; cellular response to cold [GO:0070417]; cellular response to heat [GO:0034605]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to organic substance [GO:0071310]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; positive regulation of anion transport [GO:1903793]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of sensory perception of pain [GO:1904058]; protein homotetramerization [GO:0051289]; regulation of blood circulation [GO:1903522]; regulation of neuronal action potential [GO:0098908]; response to cold [GO:0009409]; response to hydrogen peroxide [GO:0042542]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; sensory perception of pain [GO:0019233]; thermoception [GO:0050955]; urinary bladder smooth muscle contraction [GO:0014832] GO:0005216; GO:0005245; GO:0005262; GO:0005886; GO:0006816; GO:0006874; GO:0007166; GO:0009409; GO:0009410; GO:0010033; GO:0014070; GO:0014832; GO:0015267; GO:0015278; GO:0016020; GO:0016324; GO:0019233; GO:0030424; GO:0032421; GO:0034605; GO:0035774; GO:0042542; GO:0042802; GO:0048265; GO:0050955; GO:0050966; GO:0050968; GO:0050974; GO:0051289; GO:0070301; GO:0070417; GO:0070588; GO:0071244; GO:0071310; GO:0097553; GO:0097604; GO:0098908; GO:1903522; GO:1903793; GO:1904058; GO:1990760 38149 XM_044319481.1 45 88 94 95 2 NA NA NA NA NA NA 38150 XM_044313819.1 298 276 320 265 272 NA NA NA NA NA NA 38151 XM_044318765.1 23 9 15 18 45 P04323 1.46e-50 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 38152 XM_029343373.2 178 0 30 126 12 NA NA NA NA NA NA 38153 XR_006393490.1 26 0 0 0 0 NA NA NA NA NA NA 38154 XM_029345588.2 57 138 94 77 115 P42264 5.26e-80 Glutamate receptor ionotropic, kainate 3 (GluK3) (Glutamate receptor 7) (GluR-7) (GluR7) Rattus norvegicus (Rat) chemical synaptic transmission [GO:0007268]; G protein-coupled glutamate receptor signaling pathway [GO:0007216]; glutamate receptor signaling pathway [GO:0007215]; ion transmembrane transport [GO:0034220]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; regulation of membrane potential [GO:0042391]; regulation of presynaptic membrane potential [GO:0099505]; synaptic transmission, glutamatergic [GO:0035249] GO:0001640; GO:0004970; GO:0005886; GO:0007215; GO:0007216; GO:0007268; GO:0008066; GO:0015276; GO:0015277; GO:0030424; GO:0030425; GO:0032839; GO:0032983; GO:0034220; GO:0035249; GO:0038023; GO:0042391; GO:0042734; GO:0043195; GO:0043204; GO:0045211; GO:0050804; GO:0051967; GO:0098978; GO:0099505; GO:0099507; GO:1904315 38155 XR_003826435.2 0 0 0 0 11 NA NA NA NA NA NA 38156 XM_029350178.2 4676 2801 1687 3870 2665 Q92870 9.95e-58 Amyloid beta precursor protein binding family B member 2 (Amyloid-beta (A4) precursor protein-binding family B member 2) (Protein Fe65-like 1) Homo sapiens (Human) intracellular signal transduction [GO:0035556]; maintenance of lens transparency [GO:0036438]; negative regulation of cell cycle phase transition [GO:1901988]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; smooth muscle contraction [GO:0006939]; synapse organization [GO:0050808] GO:0000122; GO:0001540; GO:0005634; GO:0005737; GO:0005769; GO:0005783; GO:0005794; GO:0006355; GO:0006939; GO:0016020; GO:0030027; GO:0030426; GO:0035556; GO:0036438; GO:0045202; GO:0045944; GO:0050808; GO:1901988 38157 XM_044317843.1 0 0 6 0 0 NA NA NA NA NA NA 38158 XM_044322097.1 24 1 3 0 58 D3YXG0 4.92e-80 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 38159 XM_044322097.1 24 1 3 0 58 D3YXG0 3.33e-72 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 38160 XM_044326453.1 82 17 48 45 75 NA NA NA NA NA NA 38161 XM_044323542.1 64 25 36 222 151 NA NA NA NA NA NA 38162 XM_029358569.2 313 967 515 88 307 NA NA NA NA NA NA 38163 XR_006396058.1 205 139 61 69 170 P21127 2.63e-141 Cyclin-dependent kinase 11B (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 1) (CLK-1) (Cell division protein kinase 11B) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L1) (p58 CLK-1) Homo sapiens (Human) apoptotic process [GO:0006915]; mitotic cell cycle [GO:0000278]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell growth [GO:0001558]; regulation of centrosome cycle [GO:0046605]; regulation of DNA-templated transcription [GO:0006355]; regulation of mitotic cell cycle [GO:0007346]; regulation of mRNA processing [GO:0050684]; regulation of RNA splicing [GO:0043484] GO:0000278; GO:0000307; GO:0001558; GO:0003723; GO:0004672; GO:0004674; GO:0004693; GO:0005524; GO:0005634; GO:0005737; GO:0006355; GO:0006468; GO:0006915; GO:0007346; GO:0042981; GO:0043484; GO:0046605; GO:0050684; GO:0051726; GO:0106310 38164 XM_044323271.1 14 13 2 18 48 NA NA NA NA NA NA 38165 XR_006391687.1 185 250 121 243 202 P25122 7.45e-90 Potassium voltage-gated channel subfamily C member 1 (NGK2) (RAW2) (Voltage-gated potassium channel subunit Kv3.1) (Voltage-gated potassium channel subunit Kv4) Rattus norvegicus (Rat) brain development [GO:0007420]; cellular response to xenobiotic stimulus [GO:0071466]; cerebellum development [GO:0021549]; corpus callosum development [GO:0022038]; globus pallidus development [GO:0021759]; optic nerve development [GO:0021554]; positive regulation of ion transmembrane transport [GO:0034767]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of voltage-gated potassium channel activity [GO:1903818]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; protein tetramerization [GO:0051262]; regulation of ion transmembrane transport [GO:0034765]; regulation of potassium ion transmembrane transport [GO:1901379]; response to amine [GO:0014075]; response to auditory stimulus [GO:0010996]; response to fibroblast growth factor [GO:0071774]; response to light intensity [GO:0009642]; response to nerve growth factor [GO:1990089]; response to potassium ion [GO:0035864]; response to toxic substance [GO:0009636] GO:0005249; GO:0005251; GO:0007420; GO:0008076; GO:0009636; GO:0009642; GO:0009986; GO:0010996; GO:0014075; GO:0016020; GO:0019894; GO:0021549; GO:0021554; GO:0021759; GO:0022038; GO:0030424; GO:0030425; GO:0030673; GO:0032589; GO:0032590; GO:0032809; GO:0034765; GO:0034767; GO:0035864; GO:0042734; GO:0043025; GO:0044305; GO:0044325; GO:0045211; GO:0051260; GO:0051262; GO:0071466; GO:0071774; GO:0071805; GO:0099508; GO:1901379; GO:1901381; GO:1903818; GO:1990089 38166 XR_006391687.1 185 250 121 243 202 P25122 7.45e-90 Potassium voltage-gated channel subfamily C member 1 (NGK2) (RAW2) (Voltage-gated potassium channel subunit Kv3.1) (Voltage-gated potassium channel subunit Kv4) Rattus norvegicus (Rat) brain development [GO:0007420]; cellular response to xenobiotic stimulus [GO:0071466]; cerebellum development [GO:0021549]; corpus callosum development [GO:0022038]; globus pallidus development [GO:0021759]; optic nerve development [GO:0021554]; positive regulation of ion transmembrane transport [GO:0034767]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of voltage-gated potassium channel activity [GO:1903818]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; protein tetramerization [GO:0051262]; regulation of ion transmembrane transport [GO:0034765]; regulation of potassium ion transmembrane transport [GO:1901379]; response to amine [GO:0014075]; response to auditory stimulus [GO:0010996]; response to fibroblast growth factor [GO:0071774]; response to light intensity [GO:0009642]; response to nerve growth factor [GO:1990089]; response to potassium ion [GO:0035864]; response to toxic substance [GO:0009636] GO:0005249; GO:0005251; GO:0007420; GO:0008076; GO:0009636; GO:0009642; GO:0009986; GO:0010996; GO:0014075; GO:0016020; GO:0019894; GO:0021549; GO:0021554; GO:0021759; GO:0022038; GO:0030424; GO:0030425; GO:0030673; GO:0032589; GO:0032590; GO:0032809; GO:0034765; GO:0034767; GO:0035864; GO:0042734; GO:0043025; GO:0044305; GO:0044325; GO:0045211; GO:0051260; GO:0051262; GO:0071466; GO:0071774; GO:0071805; GO:0099508; GO:1901379; GO:1901381; GO:1903818; GO:1990089 38167 XM_044309192.1 0 0 21 13 0 NA NA NA NA NA NA 38168 XM_029350614.2 392 137 156 701 150 Q7Z6L1 6.47e-112 Tectonin beta-propeller repeat-containing protein 1 Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; macroautophagy [GO:0016236]; regulation of autophagosome maturation [GO:1901096] GO:0000421; GO:0005654; GO:0005765; GO:0006914; GO:0016236; GO:0031410; GO:0032266; GO:0032991; GO:0043231; GO:0097352; GO:1901096 38169 XM_029350614.2 392 137 156 701 150 Q7Z6L1 6.25e-69 Tectonin beta-propeller repeat-containing protein 1 Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; macroautophagy [GO:0016236]; regulation of autophagosome maturation [GO:1901096] GO:0000421; GO:0005654; GO:0005765; GO:0006914; GO:0016236; GO:0031410; GO:0032266; GO:0032991; GO:0043231; GO:0097352; GO:1901096 38170 XM_029350614.2 392 137 156 701 150 Q7Z6L1 2.68e-36 Tectonin beta-propeller repeat-containing protein 1 Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; macroautophagy [GO:0016236]; regulation of autophagosome maturation [GO:1901096] GO:0000421; GO:0005654; GO:0005765; GO:0006914; GO:0016236; GO:0031410; GO:0032266; GO:0032991; GO:0043231; GO:0097352; GO:1901096 38171 XM_029350614.2 392 137 156 701 150 Q7Z6L1 1.14e-32 Tectonin beta-propeller repeat-containing protein 1 Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; macroautophagy [GO:0016236]; regulation of autophagosome maturation [GO:1901096] GO:0000421; GO:0005654; GO:0005765; GO:0006914; GO:0016236; GO:0031410; GO:0032266; GO:0032991; GO:0043231; GO:0097352; GO:1901096 38172 XM_029335892.2 0 0 0 0 9 E7F7V7 3.27e-24 Galanin receptor 2b Danio rerio (Zebrafish) (Brachydanio rerio) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; neuropeptide signaling pathway [GO:0007218] GO:0004966; GO:0005886; GO:0007188; GO:0007218; GO:0008528 38173 XM_029333511.2 378 246 129 249 249 Q61382 1.08e-66 TNF receptor-associated factor 4 (EC 2.3.2.27) (Cysteine-rich motif associated to RING and Traf domains protein 1) Mus musculus (Mouse) activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; innate immune response [GO:0045087]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein kinase activity [GO:0045860]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; respiratory gaseous exchange by respiratory system [GO:0007585]; respiratory tube development [GO:0030323] GO:0001650; GO:0005164; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0005923; GO:0006915; GO:0007250; GO:0007585; GO:0008270; GO:0016740; GO:0019901; GO:0030323; GO:0031625; GO:0031996; GO:0042802; GO:0042981; GO:0043122; GO:0043161; GO:0045087; GO:0045860; GO:0046330; GO:0048471; GO:0050699 38174 XM_044324013.1 5 11 6 0 34 NA NA NA NA NA NA 38175 XM_029350292.2 354 190 158 204 214 NA NA NA NA NA NA 38176 XM_029351961.2 0 357 27 0 439 NA NA NA NA NA NA 38177 XM_044322536.1 1111 318 534 765 927 NA NA NA NA NA NA 38178 XM_044323923.1 26 14 11 52 77 NA NA NA NA NA NA 38179 XM_029339577.2 613 595 383 506 376 Q0E3L5 3.23e-44 Urease accessory protein F (AtUREF) Oryza sativa subsp. japonica (Rice) nitrogen compound metabolic process [GO:0006807] GO:0006807; GO:0016151 38180 XM_044324565.1 154 75 145 51 69 NA NA NA NA NA NA 38181 XM_029323752.2 2992 3989 1308 1935 2129 Q5BJI9 1.46e-71 Signal peptidase complex subunit 2 (Microsomal signal peptidase 25 kDa subunit) (SPase 25 kDa subunit) Danio rerio (Zebrafish) (Brachydanio rerio) protein targeting to ER [GO:0045047]; signal peptide processing [GO:0006465] GO:0005787; GO:0006465; GO:0045047 38182 XM_029333271.2 0 0 0 0 43 Q16281 0 Cyclic nucleotide-gated cation channel alpha-3 (Cone photoreceptor cGMP-gated channel subunit alpha) (Cyclic nucleotide-gated channel alpha-3) (CNG channel alpha-3) (CNG-3) (CNG3) Homo sapiens (Human) cation transmembrane transport [GO:0098655]; cation transport [GO:0006812]; inorganic cation import across plasma membrane [GO:0098659]; response to cAMP [GO:0051591]; response to corticosteroid [GO:0031960]; response to magnesium ion [GO:0032026]; signal transduction [GO:0007165]; visual perception [GO:0007601] GO:0005222; GO:0005223; GO:0005737; GO:0005886; GO:0006812; GO:0007165; GO:0007601; GO:0008022; GO:0015276; GO:0017071; GO:0030425; GO:0030553; GO:0031960; GO:0032026; GO:0043194; GO:0043204; GO:0044877; GO:0051591; GO:0097386; GO:0098655; GO:0098659; GO:1902495 38183 XM_029345051.2 7 81 14 0 62 P58912 9.08e-78 DELTA-alicitoxin-Pse2b (DELTA-ALTX-Pse2b) (Toxin PsTX-60B) (PTX60B) Phyllodiscus semoni (Night anemone) hemolysis in another organism [GO:0044179] GO:0005576; GO:0042151; GO:0044179; GO:0090729 38184 XM_029357802.2 2096 2348 1227 2156 1714 P60881 9.51e-68 Synaptosomal-associated protein 25 (SNAP-25) (Super protein) (SUP) (Synaptosomal-associated 25 kDa protein) Rattus norvegicus (Rat) associative learning [GO:0008306]; axonogenesis [GO:0007409]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; endosomal transport [GO:0016197]; exocytic insertion of neurotransmitter receptor to postsynaptic membrane [GO:0098967]; exocytosis [GO:0006887]; growth hormone secretion [GO:0030252]; localization [GO:0051179]; locomotory behavior [GO:0007626]; long-term memory [GO:0007616]; long-term synaptic potentiation [GO:0060291]; neuron differentiation [GO:0030182]; neurotransmitter receptor internalization [GO:0099590]; neurotransmitter secretion [GO:0007269]; positive regulation of hormone secretion [GO:0046887]; positive regulation of insulin secretion [GO:0032024]; presynaptic dense core vesicle exocytosis [GO:0099525]; regulation of establishment of protein localization [GO:0070201]; regulation of neuron projection development [GO:0010975]; regulation of synapse assembly [GO:0051963]; sleep [GO:0030431]; SNARE complex assembly [GO:0035493]; synaptic vesicle exocytosis [GO:0016079]; synaptic vesicle fusion to presynaptic active zone membrane [GO:0031629]; synaptic vesicle priming [GO:0016082]; vesicle fusion [GO:0006906] GO:0000149; GO:0001917; GO:0005249; GO:0005484; GO:0005737; GO:0005768; GO:0005802; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006906; GO:0007269; GO:0007409; GO:0007616; GO:0007626; GO:0008021; GO:0008076; GO:0008289; GO:0008306; GO:0010975; GO:0015629; GO:0016020; GO:0016079; GO:0016082; GO:0016197; GO:0017022; GO:0017075; GO:0019904; GO:0019905; GO:0030027; GO:0030175; GO:0030182; GO:0030252; GO:0030424; GO:0030426; GO:0030431; GO:0031201; GO:0031234; GO:0031629; GO:0032024; GO:0035493; GO:0036477; GO:0042734; GO:0043005; GO:0043025; GO:0043195; GO:0043229; GO:0044295; GO:0044325; GO:0045121; GO:0045202; GO:0046887; GO:0047485; GO:0048306; GO:0048471; GO:0048787; GO:0048791; GO:0051179; GO:0051963; GO:0060090; GO:0060291; GO:0070032; GO:0070033; GO:0070044; GO:0070201; GO:0097470; GO:0098793; GO:0098794; GO:0098888; GO:0098967; GO:0098978; GO:0099525; GO:0099590 38185 XM_029353236.2 134 0 93 118 45 Q4QRK0 0 Methionine aminopeptidase 1 (MAP 1) (MetAP 1) (EC 3.4.11.18) (Peptidase M 1) Danio rerio (Zebrafish) (Brachydanio rerio) protein initiator methionine removal involved in protein maturation [GO:0035551] GO:0005829; GO:0035551; GO:0046872; GO:0070006 38186 XM_044308698.1 9 26 6 19 21 NA NA NA NA NA NA 38187 XM_029328444.2 21 160 11 1 22 NA NA NA NA NA NA 38188 XR_006394486.1 0 33 0 68 3 NA NA NA NA NA NA 38189 XM_044327722.1 18647 37213 5297 20095 6521 NA NA NA NA NA NA 38190 XM_029341834.2 247 105 166 358 265 Q08DA5 7.58e-133 Pantothenate kinase 3 (EC 2.7.1.33) (Pantothenic acid kinase 3) Bos taurus (Bovine) coenzyme A biosynthetic process [GO:0015937]; phosphorylation [GO:0016310] GO:0004594; GO:0005524; GO:0005634; GO:0005829; GO:0015937; GO:0016310; GO:0019842; GO:0042803; GO:1905502 38191 XM_044317612.1 146 91 99 312 28 P49183 7.54e-77 Deoxyribonuclease-1 (EC 3.1.21.1) (Deoxyribonuclease I) (DNase I) Mus musculus (Mouse) apoptotic process [GO:0006915]; DNA catabolic process [GO:0006308]; DNA catabolic process, endonucleolytic [GO:0000737]; neutrophil activation involved in immune response [GO:0002283]; regulation of acute inflammatory response [GO:0002673]; regulation of neutrophil mediated cytotoxicity [GO:0070948] GO:0000737; GO:0002283; GO:0002673; GO:0003677; GO:0003779; GO:0004530; GO:0004536; GO:0005576; GO:0005634; GO:0005635; GO:0006308; GO:0006915; GO:0042588; GO:0070948 38192 XM_044307198.1 12 33 10 12 53 Q5PQ59 6.75e-87 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6 (EC 1.14.11.-) (Alkylated DNA repair protein alkB homolog 6) Xenopus laevis (African clawed frog) NA GO:0005634; GO:0005737; GO:0046872; GO:0051213 38193 XM_029356973.2 510 572 347 966 520 Q8IYW2 0 Cilia- and flagella-associated protein 46 (Tetratricopeptide repeat protein 40) Homo sapiens (Human) axoneme assembly [GO:0035082]; cilium movement involved in cell motility [GO:0060294] GO:0005930; GO:0035082; GO:0060294 38194 XM_029356973.2 510 572 347 966 520 Q8IYW2 2.39e-75 Cilia- and flagella-associated protein 46 (Tetratricopeptide repeat protein 40) Homo sapiens (Human) axoneme assembly [GO:0035082]; cilium movement involved in cell motility [GO:0060294] GO:0005930; GO:0035082; GO:0060294 38195 XM_029356973.2 510 572 347 966 520 Q8IYW2 3.66e-54 Cilia- and flagella-associated protein 46 (Tetratricopeptide repeat protein 40) Homo sapiens (Human) axoneme assembly [GO:0035082]; cilium movement involved in cell motility [GO:0060294] GO:0005930; GO:0035082; GO:0060294 38196 XM_029342062.2 450 139 351 457 606 Q5RF48 0 Methanethiol oxidase (MTO) (EC 1.8.3.4) (Selenium-binding protein 1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) protein transport [GO:0015031] GO:0005634; GO:0005829; GO:0008430; GO:0015031; GO:0016020; GO:0018549 38197 XM_029330525.2 375 926 458 647 184 NA NA NA NA NA NA 38198 XM_029356706.2 429 284 161 631 501 NA NA NA NA NA NA 38199 XM_029350552.2 18 574 240 835 717 Q9BST9 8.67e-53 Rhotekin Homo sapiens (Human) actomyosin contractile ring assembly [GO:0000915]; apoptotic process [GO:0006915]; mitotic cytokinesis [GO:0000281]; regulation of apoptotic process [GO:0042981]; Rho protein signal transduction [GO:0007266]; septin ring organization [GO:0031106]; signal transduction [GO:0007165] GO:0000281; GO:0000915; GO:0005095; GO:0005525; GO:0005826; GO:0005829; GO:0006915; GO:0007165; GO:0007266; GO:0031106; GO:0031267; GO:0042981 38200 XM_029331021.2 0 0 11 0 0 NA NA NA NA NA NA 38201 XM_044309549.1 0 0 0 0 7 NA NA NA NA NA NA 38202 XM_044312346.1 0 7 0 0 2 NA NA NA NA NA NA 38203 XM_044313412.1 19 1 15 3 0 NA NA NA NA NA NA 38204 XM_029355832.2 1483 1014 838 1347 1288 Q6PCN3 2.63e-111 Tau-tubulin kinase 1 (EC 2.7.11.1) Mus musculus (Mouse) learning or memory [GO:0007611]; negative regulation of gene expression [GO:0010629]; negative regulation of protein binding [GO:0032091]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cyclin-dependent protein kinase activity [GO:1904031]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of gene expression [GO:0010628]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of protein polymerization [GO:0032273]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165] GO:0004674; GO:0004713; GO:0005524; GO:0005634; GO:0005654; GO:0005829; GO:0005875; GO:0006468; GO:0007165; GO:0007611; GO:0010628; GO:0010629; GO:0018105; GO:0018107; GO:0018108; GO:0032091; GO:0032273; GO:0043025; GO:0048156; GO:0048471; GO:0050321; GO:0106310; GO:1903980; GO:1904031; GO:2001056 38205 XM_029342137.2 3483 1846 1670 3570 2440 A6QNP3 6.05e-28 Protein phosphatase 1 regulatory subunit 3B Bos taurus (Bovine) glycogen metabolic process [GO:0005977]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of glycogen catabolic process [GO:0005981] GO:0000164; GO:0005977; GO:0005979; GO:0005981; GO:0008157; GO:0019888; GO:2001069 38206 XM_029344551.2 549 303 71 275 198 P0DPD6 3.85e-166 Endothelin-converting enzyme 2 (ECE-2) (EC 3.4.24.71) Homo sapiens (Human) cell-cell signaling [GO:0007267]; G protein-coupled receptor signaling pathway [GO:0007186]; methylation [GO:0032259]; peptide hormone processing [GO:0016486]; protein processing [GO:0016485] GO:0000139; GO:0004222; GO:0005886; GO:0007186; GO:0007267; GO:0008168; GO:0016485; GO:0016486; GO:0030658; GO:0030659; GO:0032259; GO:0046872 38207 XM_029334726.2 87 179 2285 102 247 Q96DM1 8.75e-52 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 38208 XM_044316909.1 1928 169 406 1940 119 NA NA NA NA NA NA 38209 XM_044320047.1 2 0 11 1 1 NA NA NA NA NA NA 38210 XR_006392269.1 3 0 12 3 0 NA NA NA NA NA NA 38211 XM_044319712.1 294 155 60 102 85 Q23915 1.49e-26 Probable serine/threonine-protein kinase kinX (EC 2.7.11.1) Dictyostelium discoideum (Social amoeba) protein phosphorylation [GO:0006468]; signal transduction [GO:0007165] GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0006468; GO:0007165; GO:0106310 38212 XM_044321927.1 0 0 0 25 8 NA NA NA NA NA NA 38213 XM_044314089.1 78 17 18 18 40 NA NA NA NA NA NA 38214 XR_003825095.2 15 0 3 7 2 NA NA NA NA NA NA 38215 XM_029351564.2 753 569 535 1138 1069 Q75N73 4.64e-70 Metal cation symporter ZIP14 (Factor for adipocyte differentiation 123) (FAD-123) (Solute carrier family 39 member 14) (Zrt- and Irt-like protein 14) (ZIP-14) Mus musculus (Mouse) cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; cellular zinc ion homeostasis [GO:0006882]; chondrocyte differentiation [GO:0002062]; gluconeogenesis [GO:0006094]; import across plasma membrane [GO:0098739]; inorganic cation transmembrane transport [GO:0098662]; insulin receptor signaling pathway [GO:0008286]; iron import into cell [GO:0033212]; iron ion transmembrane transport [GO:0034755]; iron ion transport [GO:0006826]; manganese ion homeostasis [GO:0055071]; manganese ion transmembrane transport [GO:0071421]; negative regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051344]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; regulation of hormone levels [GO:0010817]; zinc ion import across plasma membrane [GO:0071578]; zinc ion transmembrane transport [GO:0071577]; zinc ion transport [GO:0006829] GO:0002062; GO:0005381; GO:0005384; GO:0005385; GO:0005765; GO:0005886; GO:0006094; GO:0006826; GO:0006829; GO:0006882; GO:0008286; GO:0010817; GO:0015086; GO:0015093; GO:0015296; GO:0016020; GO:0016323; GO:0016324; GO:0031901; GO:0031902; GO:0032869; GO:0033212; GO:0034755; GO:0045745; GO:0051344; GO:0055071; GO:0071333; GO:0071421; GO:0071577; GO:0071578; GO:0098662; GO:0098739 38216 XM_029338539.2 1024 733 431 831 711 Q9DDT2 3.37e-22 Phosphoinositide 3-kinase adapter protein 1 (B-cell adapter for phosphoinositide 3-kinase) (B-cell phosphoinositide 3-kinase adapter protein 1) Gallus gallus (Chicken) cellular response to insulin stimulus [GO:0032869]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; regulation of inflammatory response [GO:0050727]; regulation of kinase activity [GO:0043549]; regulation of phosphorylation [GO:0042325]; toll-like receptor 2 signaling pathway [GO:0034134]; toll-like receptor 4 signaling pathway [GO:0034142]; toll-like receptor 7 signaling pathway [GO:0034154]; toll-like receptor 9 signaling pathway [GO:0034162]; TOR signaling [GO:0031929] GO:0005102; GO:0005829; GO:0005886; GO:0014068; GO:0016020; GO:0031929; GO:0032869; GO:0034134; GO:0034142; GO:0034154; GO:0034162; GO:0036312; GO:0042325; GO:0043549; GO:0050727 38217 XM_029356604.2 8 3 0 12 15 NA NA NA NA NA NA 38218 XM_044314797.1 1514 6611 2202 4593 3922 NA NA NA NA NA NA 38219 XM_029335796.2 891 241 380 606 736 B3EWZ8 0 Ectin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 38220 XM_029357545.2 448 409 314 558 436 Q9NX08 1.29e-29 COMM domain-containing protein 8 Homo sapiens (Human) NA GO:0005654; GO:0005829 38221 XM_044319678.1 38 20 19 23 38 NA NA NA NA NA NA 38222 XM_044314648.1 62 5 59 77 82 Q96AY4 2.16e-170 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38223 XM_044314648.1 62 5 59 77 82 Q96AY4 1.61e-158 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38224 XM_044314648.1 62 5 59 77 82 Q96AY4 8.31e-139 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38225 XM_044314648.1 62 5 59 77 82 Q96AY4 4.85e-130 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38226 XM_044314648.1 62 5 59 77 82 Q96AY4 7.01e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38227 XM_029347090.2 459 342 316 539 496 Q9D1P0 4.95e-49 39S ribosomal protein L13, mitochondrial (L13mt) (MRP-L13) Mus musculus (Mouse) mitochondrial translation [GO:0032543]; negative regulation of translation [GO:0017148]; translation [GO:0006412] GO:0003729; GO:0003735; GO:0005739; GO:0005743; GO:0005761; GO:0005762; GO:0005840; GO:0006412; GO:0017148; GO:0032543 38228 XM_029343973.2 598 334 189 349 236 Q96IK5 1.91e-120 Germ cell-less protein-like 1 (Spermatogenesis-associated protein 29) Homo sapiens (Human) germ cell development [GO:0007281]; spermatogenesis [GO:0007283] GO:0005634; GO:0007281; GO:0007283; GO:0016363; GO:0042802 38229 XM_044308986.1 236 139 82 192 196 P20664 1.23e-161 DNA primase small subunit (EC 2.7.7.102) (DNA primase 49 kDa subunit) (p49) Mus musculus (Mouse) DNA replication initiation [GO:0006270]; DNA replication, synthesis of RNA primer [GO:0006269] GO:0000287; GO:0003896; GO:0005658; GO:0006269; GO:0006270; GO:0008270; GO:0032553 38230 XM_029348840.2 200 80 95 89 150 Q9FWW9 1.19e-72 Flavin-containing monooxygenase FMO GS-OX-like 2 (EC 1.8.-.-) (Flavin-monooxygenase glucosinolate S-oxygenase-like 2) Arabidopsis thaliana (Mouse-ear cress) defense response to fungus [GO:0050832] GO:0004499; GO:0050660; GO:0050661; GO:0050832 38231 XM_044321642.1 1716 1324 1030 1806 953 Q6IP59 9.01e-164 Choline transporter-like protein 2 (Solute carrier family 44 member 2) Xenopus laevis (African clawed frog) NA GO:0016020; GO:0022857 38232 XM_044318461.1 1212 827 510 690 1582 Q6ZZY0 0 Cryptochrome-1 Sylvia borin (Garden warbler) circadian rhythm [GO:0007623]; negative regulation of gluconeogenesis [GO:0045721]; response to light stimulus [GO:0009416] GO:0000166; GO:0005634; GO:0005829; GO:0007623; GO:0009416; GO:0009881; GO:0042622; GO:0045721; GO:0097381 38233 XM_044324172.1 2 2 305 0 150 NA NA NA NA NA NA 38234 XM_029344072.2 0 0 16 27 0 NA NA NA NA NA NA 38235 XR_006396237.1 336 229 284 434 528 NA NA NA NA NA NA 38236 XM_029334969.2 571 386 294 383 445 Q6DE94 1.3e-22 Nuclear cap-binding protein subunit 3 Xenopus laevis (African clawed frog) 7-methylguanosine mRNA capping [GO:0006370]; mRNA transport [GO:0051028] GO:0000340; GO:0003729; GO:0005634; GO:0005737; GO:0006370; GO:0051028 38237 XM_029329478.2 146 119 115 129 113 Q7Z6V5 3.48e-52 tRNA-specific adenosine deaminase 2 (EC 3.5.4.33) (Deaminase domain-containing protein 1) (tRNA-specific adenosine-34 deaminase subunit ADAT2) Homo sapiens (Human) tRNA wobble adenosine to inosine editing [GO:0002100] GO:0002100; GO:0005654; GO:0008270; GO:0052717 38238 XM_029333502.2 0 0 0 9 29 P58027 2.65e-111 Amine oxidase [flavin-containing] A (EC 1.4.3.21) (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A) Canis lupus familiaris (Dog) (Canis familiaris) catecholamine metabolic process [GO:0006584]; neurotransmitter catabolic process [GO:0042135] GO:0005739; GO:0005741; GO:0006584; GO:0008131; GO:0042135; GO:0050660; GO:0052595; GO:0052596; GO:0097621 38239 XM_029333502.2 0 0 0 9 29 P58027 2.65e-111 Amine oxidase [flavin-containing] A (EC 1.4.3.21) (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A) Canis lupus familiaris (Dog) (Canis familiaris) catecholamine metabolic process [GO:0006584]; neurotransmitter catabolic process [GO:0042135] GO:0005739; GO:0005741; GO:0006584; GO:0008131; GO:0042135; GO:0050660; GO:0052595; GO:0052596; GO:0097621 38240 XM_044319287.1 421 142 72 248 238 NA NA NA NA NA NA 38241 XR_006394719.1 59 4 0 0 31 NA NA NA NA NA NA 38242 XM_044327939.1 3 1 10 3 12 Q09575 7.8e-24 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 38243 XM_044308449.1 1705 1607 929 1227 798 Q1JPX3 0 Phenylalanine--tRNA ligase alpha subunit (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase alpha subunit) (PheRS) Danio rerio (Zebrafish) (Brachydanio rerio) anatomical structure development [GO:0048856]; phenylalanyl-tRNA aminoacylation [GO:0006432]; protein heterotetramerization [GO:0051290] GO:0000049; GO:0000287; GO:0004826; GO:0005524; GO:0005737; GO:0006432; GO:0009328; GO:0048856; GO:0051290 38244 XM_044318222.1 528 494 316 702 572 Q8C1D8 7.82e-86 Protein IWS1 homolog (IWS1-like protein) Mus musculus (Mouse) mRNA processing [GO:0006397]; poly(A)+ mRNA export from nucleus [GO:0016973]; regulation of histone H3-K36 trimethylation [GO:2001253]; regulation of histone H4 acetylation [GO:0090239]; regulation of mRNA export from nucleus [GO:0010793]; regulation of mRNA processing [GO:0050684]; RNA splicing [GO:0008380] GO:0005634; GO:0005654; GO:0006397; GO:0008380; GO:0010793; GO:0016973; GO:0050684; GO:0090239; GO:2001253 38245 XM_029339733.2 0 21 0 0 81 Q6GLQ4 1.06e-25 Serine/threonine-protein phosphatase 1 regulatory subunit 10 Xenopus laevis (African clawed frog) NA GO:0004864; GO:0005634; GO:0046872 38246 XM_029339733.2 0 21 0 0 81 Q6GLQ4 2.32e-25 Serine/threonine-protein phosphatase 1 regulatory subunit 10 Xenopus laevis (African clawed frog) NA GO:0004864; GO:0005634; GO:0046872 38247 XM_029347001.2 1172 949 465 823 638 Q2HJ46 3.87e-21 E3 ubiquitin-protein ligase RNF8 (EC 2.3.2.27) (RING finger protein 8) (RING-type E3 ubiquitin transferase RNF8) Bos taurus (Bovine) cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair [GO:0006302]; double-strand break repair via nonhomologous end joining [GO:0006303]; histone H2A K63-linked ubiquitination [GO:0070535]; histone H2A ubiquitination [GO:0033522]; histone H2B ubiquitination [GO:0033523]; isotype switching [GO:0045190]; negative regulation of transcription elongation by RNA polymerase II [GO:0034244]; positive regulation of DNA repair [GO:0045739]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; response to ionizing radiation [GO:0010212]; sperm DNA condensation [GO:0035092]; spermatid development [GO:0007286]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000151; GO:0000781; GO:0003682; GO:0004842; GO:0005634; GO:0005737; GO:0005829; GO:0006302; GO:0006303; GO:0006511; GO:0006974; GO:0007049; GO:0007286; GO:0008270; GO:0010212; GO:0016567; GO:0030496; GO:0033522; GO:0033523; GO:0034244; GO:0035092; GO:0035861; GO:0042393; GO:0042803; GO:0043130; GO:0045190; GO:0045739; GO:0051301; GO:0061630; GO:0070534; GO:0070535; GO:0070936 38248 XM_044313278.1 130 121 94 194 98 P51687 0 Sulfite oxidase, mitochondrial (EC 1.8.3.1) Homo sapiens (Human) sulfur compound metabolic process [GO:0006790] GO:0005739; GO:0005758; GO:0005759; GO:0006790; GO:0008482; GO:0020037; GO:0030151; GO:0043546 38249 XM_029325931.2 1021 710 517 1433 607 P07953 6.76e-163 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 (6PF-2-K/Fru-2,6-P2ase 1) (PFK/FBPase 1) (6PF-2-K/Fru-2,6-P2ase liver isozyme) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)] Rattus norvegicus (Rat) animal organ regeneration [GO:0031100]; carbohydrate phosphorylation [GO:0046835]; fructose 2,6-bisphosphate metabolic process [GO:0006003]; fructose metabolic process [GO:0006000]; positive regulation of glucokinase activity [GO:0033133]; response to cAMP [GO:0051591]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to insulin [GO:0032868]; response to starvation [GO:0042594] GO:0003873; GO:0004331; GO:0005524; GO:0005829; GO:0006000; GO:0006003; GO:0019900; GO:0031100; GO:0032868; GO:0033133; GO:0033762; GO:0042594; GO:0042802; GO:0043540; GO:0046835; GO:0051384; GO:0051591; GO:0070095 38250 XM_029357865.2 70 59 102 94 70 P51028 9.15e-73 Protein Wnt-8a Danio rerio (Zebrafish) (Brachydanio rerio) anterior/posterior pattern specification [GO:0009952]; brain segmentation [GO:0035284]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation [GO:0060823]; cell fate commitment [GO:0045165]; cell migration involved in gastrulation [GO:0042074]; cell proliferation involved in pronephros development [GO:0039015]; central nervous system development [GO:0007417]; determination of dorsal identity [GO:0048263]; dorsal/ventral pattern formation [GO:0009953]; ectoderm development [GO:0007398]; embryonic axis specification [GO:0000578]; endoderm development [GO:0007492]; eye development [GO:0001654]; hindbrain development [GO:0030902]; mesoderm development [GO:0007498]; mesoderm formation [GO:0001707]; mesodermal cell fate commitment [GO:0001710]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; neural crest cell fate specification [GO:0014036]; neural plate anterior/posterior regionalization [GO:0021999]; neural plate pattern specification [GO:0060896]; neuron differentiation [GO:0030182]; notochord development [GO:0030903]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of fibroblast growth factor receptor signaling pathway [GO:0045743]; positive regulation of gene expression [GO:0010628]; post-anal tail morphogenesis [GO:0036342]; regulation of anterior head development [GO:2000742]; regulation of cell population proliferation [GO:0042127]; somitogenesis [GO:0001756]; Spemann organizer formation [GO:0060061]; spinal cord anterior/posterior patterning [GO:0021512]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in dorsal/ventral axis specification [GO:0044332] GO:0000578; GO:0001654; GO:0001707; GO:0001710; GO:0001756; GO:0005109; GO:0005125; GO:0005615; GO:0007398; GO:0007417; GO:0007492; GO:0007498; GO:0009952; GO:0009953; GO:0009986; GO:0010628; GO:0014036; GO:0016055; GO:0021512; GO:0021999; GO:0030182; GO:0030902; GO:0030903; GO:0035284; GO:0036342; GO:0039015; GO:0042074; GO:0042127; GO:0044332; GO:0045165; GO:0045743; GO:0048263; GO:0060061; GO:0060070; GO:0060823; GO:0060896; GO:0090090; GO:0090263; GO:0097189; GO:2000742 38251 XM_029342706.2 1351 1008 680 1077 1326 Q4VBT5 3.56e-105 Probable E3 ubiquitin-protein ligase makorin-1 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase makorin-1) Danio rerio (Zebrafish) (Brachydanio rerio) protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567] GO:0000209; GO:0016567; GO:0046872; GO:0061630 38252 XM_029356716.2 653 421 204 480 249 Q6DE37 5.51e-95 Glucoside xylosyltransferase 2 (EC 2.4.2.42) (Glycosyltransferase 8 domain-containing protein 4) Xenopus laevis (African clawed frog) O-glycan processing [GO:0016266] GO:0016020; GO:0016266; GO:0035252; GO:0140563 38253 XM_029348786.2 0 0 16 0 46 Q8BIK4 0 Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin-1) (Zizimin-1) Mus musculus (Mouse) positive regulation of GTPase activity [GO:0043547]; small GTPase mediated signal transduction [GO:0007264] GO:0005085; GO:0007264; GO:0012505; GO:0016020; GO:0031267; GO:0043547 38254 XM_044315128.1 0 6 3 0 0 NA NA NA NA NA NA 38255 XM_044308231.1 169 43 233 106 64 Q9BU40 1.98e-26 Chordin-like protein 1 (Neuralin-1) (Neurogenesin-1) (Ventroptin) Homo sapiens (Human) AMPA glutamate receptor clustering [GO:0097113]; BMP signaling pathway [GO:0030509]; cell differentiation [GO:0030154]; embryonic axis specification [GO:0000578]; excitatory chemical synaptic transmission [GO:0098976]; eye development [GO:0001654]; negative regulation of BMP signaling pathway [GO:0030514]; ossification [GO:0001503]; regulation of synaptic plasticity [GO:0048167]; synapse maturation [GO:0060074] GO:0000578; GO:0001503; GO:0001654; GO:0005576; GO:0005788; GO:0005886; GO:0030154; GO:0030509; GO:0030514; GO:0036122; GO:0045202; GO:0048167; GO:0050431; GO:0060074; GO:0097113; GO:0098976 38256 XM_029357484.2 176 218 95 290 137 NA NA NA NA NA NA 38257 XM_029340512.2 0 13 3 1 1 NA NA NA NA NA NA 38258 XM_029339379.2 0 44 84 72 35 NA NA NA NA NA NA 38259 XM_044325675.1 436 631 236 670 442 P16260 3.58e-86 Solute carrier family 25 member 16 (Graves disease autoantigen) (GDA) (Graves disease carrier protein) (GDC) (Mitochondrial solute carrier protein homolog) Homo sapiens (Human) adenine nucleotide transport [GO:0051503]; coenzyme A biosynthetic process [GO:0015937]; mitochondrial transport [GO:0006839] GO:0005739; GO:0005743; GO:0006839; GO:0015215; GO:0015291; GO:0015297; GO:0015937; GO:0051503 38260 XM_044307944.1 378 349 65 452 540 NA NA NA NA NA NA 38261 XM_044322817.1 16 5 0 7 22 Q8CBH5 1.41e-40 Major facilitator superfamily domain-containing protein 6 (Macrophage MHC class I receptor 2) Mus musculus (Mouse) adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590] GO:0002250; GO:0005886; GO:0016020; GO:0032393; GO:0042288; GO:0042590 38262 XM_044328436.1 44 6 21 39 41 NA NA NA NA NA NA 38263 XM_044318103.1 23 40 49 765 47 NA NA NA NA NA NA 38264 XM_029333920.2 555 483 272 577 420 Q6AYK1 8.75e-26 RNA-binding protein with serine-rich domain 1 Rattus norvegicus (Rat) mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of apoptotic process [GO:0043065]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381] GO:0000184; GO:0000381; GO:0000398; GO:0003730; GO:0005634; GO:0005654; GO:0005737; GO:0016607; GO:0043065; GO:0048025; GO:0061574 38265 XM_029348730.2 2328 4552 3175 2655 4522 Q8IZQ5 2.02e-24 Selenoprotein H (SelH) Homo sapiens (Human) NA GO:0003723; GO:0005794 38266 XR_006393797.1 29 34 56 30 35 NA NA NA NA NA NA 38267 XM_029327366.2 1594 1024 1176 1244 1428 Q9D1A2 0 Cytosolic non-specific dipeptidase (EC 3.4.13.18) (CNDP dipeptidase 2) (Glutamate carboxypeptidase-like protein 1) (Threonyl dipeptidase) Mus musculus (Mouse) proteolysis [GO:0006508] GO:0004180; GO:0005654; GO:0005829; GO:0006508; GO:0008233; GO:0016805; GO:0046872; GO:0070573; GO:0103046 38268 XM_029350536.2 300 228 270 269 84 NA NA NA NA NA NA 38269 XM_029347977.2 71 152 59 43 81 O88544 0 COP9 signalosome complex subunit 4 (SGN4) (Signalosome subunit 4) (JAB1-containing signalosome subunit 4) Mus musculus (Mouse) protein deneddylation [GO:0000338] GO:0000338; GO:0005634; GO:0005737; GO:0008021; GO:0008180; GO:0016607; GO:0030054 38270 XM_029354897.2 1050 1007 606 1652 1360 NA NA NA NA NA NA 38271 XM_029350546.2 388 313 272 320 691 Q58EK5 3.23e-57 Tudor domain-containing protein 1 Danio rerio (Zebrafish) (Brachydanio rerio) DNA methylation involved in gamete generation [GO:0043046]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; P granule organization [GO:0030719]; piRNA processing [GO:0034587]; RNA-mediated gene silencing [GO:0031047]; spermatogenesis [GO:0007283] GO:0005737; GO:0007281; GO:0007283; GO:0030719; GO:0031047; GO:0034584; GO:0034587; GO:0043046; GO:0043186; GO:0046872; GO:0051321; GO:0071546 38272 XM_029350546.2 388 313 272 320 691 Q58EK5 3.14e-40 Tudor domain-containing protein 1 Danio rerio (Zebrafish) (Brachydanio rerio) DNA methylation involved in gamete generation [GO:0043046]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; P granule organization [GO:0030719]; piRNA processing [GO:0034587]; RNA-mediated gene silencing [GO:0031047]; spermatogenesis [GO:0007283] GO:0005737; GO:0007281; GO:0007283; GO:0030719; GO:0031047; GO:0034584; GO:0034587; GO:0043046; GO:0043186; GO:0046872; GO:0051321; GO:0071546 38273 XM_029350546.2 388 313 272 320 691 Q58EK5 1.51e-27 Tudor domain-containing protein 1 Danio rerio (Zebrafish) (Brachydanio rerio) DNA methylation involved in gamete generation [GO:0043046]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; P granule organization [GO:0030719]; piRNA processing [GO:0034587]; RNA-mediated gene silencing [GO:0031047]; spermatogenesis [GO:0007283] GO:0005737; GO:0007281; GO:0007283; GO:0030719; GO:0031047; GO:0034584; GO:0034587; GO:0043046; GO:0043186; GO:0046872; GO:0051321; GO:0071546 38274 XM_029329323.2 45 37 76 62 72 Q8CDK2 0 Cytosolic carboxypeptidase 2 (EC 3.4.17.-) (ATP/GTP-binding protein-like 2) (Protein deglutamylase CCP2) Mus musculus (Mouse) protein side chain deglutamylation [GO:0035610]; proteolysis [GO:0006508] GO:0004181; GO:0005814; GO:0005829; GO:0006508; GO:0008270; GO:0035610; GO:0036064 38275 XM_029330800.2 820 744 392 638 1244 NA NA NA NA NA NA 38276 XM_029331002.2 315 305 100 292 215 O43257 1.08e-42 Zinc finger HIT domain-containing protein 1 (Cyclin-G1-binding protein 1) (Zinc finger protein subfamily 4A member 1) (p18 Hamlet) Homo sapiens (Human) calcium ion homeostasis [GO:0055074]; chromatin remodeling [GO:0006338]; heart process [GO:0003015]; intestinal stem cell homeostasis [GO:0036335]; muscle cell differentiation [GO:0042692]; positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:1902164]; positive regulation of lymphoid progenitor cell differentiation [GO:1905458]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; regulation of DNA-templated transcription [GO:0006355] GO:0000786; GO:0000812; GO:0003015; GO:0005634; GO:0005654; GO:0006338; GO:0006355; GO:0031491; GO:0036335; GO:0042393; GO:0042692; GO:0046872; GO:0055074; GO:0060261; GO:0140849; GO:1902164; GO:1905458 38277 XM_044314539.1 8 12 14 17 33 NA NA NA NA NA NA 38278 XM_044314756.1 0 0 1 10 0 Q9UBN7 4.11e-40 Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-) Homo sapiens (Human) aggresome assembly [GO:0070842]; autophagy [GO:0006914]; axonal transport of mitochondrion [GO:0019896]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to misfolded protein [GO:0071218]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to topologically incorrect protein [GO:0035967]; cilium assembly [GO:0060271]; cilium disassembly [GO:0061523]; collateral sprouting [GO:0048668]; dendritic spine morphogenesis [GO:0060997]; epigenetic regulation of gene expression [GO:0040029]; histone deacetylation [GO:0016575]; Hsp90 deacetylation [GO:0070846]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of protein-containing complex disassembly [GO:0043242]; negative regulation of proteolysis [GO:0045861]; negative regulation of transcription by RNA polymerase II [GO:0000122]; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:0061734]; peptidyl-lysine deacetylation [GO:0034983]; polyubiquitinated misfolded protein transport [GO:0070845]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of hydrogen peroxide-mediated programmed cell death [GO:1901300]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of tubulin deacetylation [GO:0090044]; protein deacetylation [GO:0006476]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; protein-containing complex disassembly [GO:0032984]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of autophagy [GO:0010506]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of establishment of protein localization [GO:0070201]; regulation of fat cell differentiation [GO:0045598]; regulation of macroautophagy [GO:0016241]; regulation of microtubule-based movement [GO:0060632]; regulation of protein stability [GO:0031647]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]; response to dexamethasone [GO:0071548]; response to growth factor [GO:0070848]; response to immobilization stress [GO:0035902]; response to misfolded protein [GO:0051788]; tubulin deacetylation [GO:0090042]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] GO:0000118; GO:0000122; GO:0000209; GO:0000978; GO:0001222; GO:0001975; GO:0003779; GO:0004407; GO:0005634; GO:0005654; GO:0005737; GO:0005771; GO:0005813; GO:0005829; GO:0005874; GO:0005875; GO:0005901; GO:0006476; GO:0006515; GO:0006886; GO:0006914; GO:0007026; GO:0008013; GO:0008017; GO:0008270; GO:0010506; GO:0010634; GO:0010727; GO:0016234; GO:0016235; GO:0016241; GO:0016575; GO:0019896; GO:0019899; GO:0030424; GO:0030425; GO:0031252; GO:0031333; GO:0031593; GO:0031625; GO:0031647; GO:0031648; GO:0032418; GO:0032984; GO:0033138; GO:0033558; GO:0034983; GO:0035902; GO:0035967; GO:0036064; GO:0040029; GO:0042826; GO:0042903; GO:0043014; GO:0043130; GO:0043162; GO:0043204; GO:0043242; GO:0045598; GO:0045861; GO:0045892; GO:0048156; GO:0048471; GO:0048487; GO:0048668; GO:0048843; GO:0050775; GO:0051354; GO:0051412; GO:0051787; GO:0051788; GO:0051879; GO:0051968; GO:0060271; GO:0060632; GO:0060765; GO:0060997; GO:0061523; GO:0061734; GO:0070201; GO:0070301; GO:0070840; GO:0070842; GO:0070845; GO:0070846; GO:0070848; GO:0071218; GO:0071374; GO:0071548; GO:0090042; GO:0090044; GO:1901300; GO:1901984; GO:1903146; GO:1903223; GO:1904056; GO:1904115; GO:2000273 38279 XM_044314756.1 0 0 1 10 0 Q9UBN7 2.07e-34 Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-) Homo sapiens (Human) aggresome assembly [GO:0070842]; autophagy [GO:0006914]; axonal transport of mitochondrion [GO:0019896]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to misfolded protein [GO:0071218]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to topologically incorrect protein [GO:0035967]; cilium assembly [GO:0060271]; cilium disassembly [GO:0061523]; collateral sprouting [GO:0048668]; dendritic spine morphogenesis [GO:0060997]; epigenetic regulation of gene expression [GO:0040029]; histone deacetylation [GO:0016575]; Hsp90 deacetylation [GO:0070846]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of protein-containing complex disassembly [GO:0043242]; negative regulation of proteolysis [GO:0045861]; negative regulation of transcription by RNA polymerase II [GO:0000122]; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:0061734]; peptidyl-lysine deacetylation [GO:0034983]; polyubiquitinated misfolded protein transport [GO:0070845]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of hydrogen peroxide-mediated programmed cell death [GO:1901300]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of tubulin deacetylation [GO:0090044]; protein deacetylation [GO:0006476]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; protein-containing complex disassembly [GO:0032984]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of autophagy [GO:0010506]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of establishment of protein localization [GO:0070201]; regulation of fat cell differentiation [GO:0045598]; regulation of macroautophagy [GO:0016241]; regulation of microtubule-based movement [GO:0060632]; regulation of protein stability [GO:0031647]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]; response to dexamethasone [GO:0071548]; response to growth factor [GO:0070848]; response to immobilization stress [GO:0035902]; response to misfolded protein [GO:0051788]; tubulin deacetylation [GO:0090042]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] GO:0000118; GO:0000122; GO:0000209; GO:0000978; GO:0001222; GO:0001975; GO:0003779; GO:0004407; GO:0005634; GO:0005654; GO:0005737; GO:0005771; GO:0005813; GO:0005829; GO:0005874; GO:0005875; GO:0005901; GO:0006476; GO:0006515; GO:0006886; GO:0006914; GO:0007026; GO:0008013; GO:0008017; GO:0008270; GO:0010506; GO:0010634; GO:0010727; GO:0016234; GO:0016235; GO:0016241; GO:0016575; GO:0019896; GO:0019899; GO:0030424; GO:0030425; GO:0031252; GO:0031333; GO:0031593; GO:0031625; GO:0031647; GO:0031648; GO:0032418; GO:0032984; GO:0033138; GO:0033558; GO:0034983; GO:0035902; GO:0035967; GO:0036064; GO:0040029; GO:0042826; GO:0042903; GO:0043014; GO:0043130; GO:0043162; GO:0043204; GO:0043242; GO:0045598; GO:0045861; GO:0045892; GO:0048156; GO:0048471; GO:0048487; GO:0048668; GO:0048843; GO:0050775; GO:0051354; GO:0051412; GO:0051787; GO:0051788; GO:0051879; GO:0051968; GO:0060271; GO:0060632; GO:0060765; GO:0060997; GO:0061523; GO:0061734; GO:0070201; GO:0070301; GO:0070840; GO:0070842; GO:0070845; GO:0070846; GO:0070848; GO:0071218; GO:0071374; GO:0071548; GO:0090042; GO:0090044; GO:1901300; GO:1901984; GO:1903146; GO:1903223; GO:1904056; GO:1904115; GO:2000273 38280 XM_029342745.2 217 49 145 391 128 NA NA NA NA NA NA 38281 XM_044315937.1 18 18 1 25 25 Q6ING9 2.88e-58 Protein phosphatase 1K, mitochondrial (EC 3.1.3.16) (Protein phosphatase 2C isoform kappa) (PP2C-kappa) Xenopus laevis (African clawed frog) protein dephosphorylation [GO:0006470] GO:0005759; GO:0006470; GO:0017018; GO:0046872 38282 XR_006396657.1 829 813 1086 721 846 NA NA NA NA NA NA 38283 XM_029345965.2 57 23 4 39 122 NA NA NA NA NA NA 38284 XM_029348319.2 1133 655 472 819 774 Q96M96 4.93e-127 FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament-binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cytoskeleton organization [GO:0007010]; filopodium assembly [GO:0046847]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056] GO:0001726; GO:0003779; GO:0005085; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0007010; GO:0008360; GO:0030027; GO:0030036; GO:0030175; GO:0031267; GO:0043087; GO:0046847; GO:0046872; GO:0051056 38285 XM_044328886.1 2 14 6 29 6 Q7TN88 1.42e-63 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 38286 XM_044328886.1 2 14 6 29 6 Q7TN88 2.04e-49 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 38287 XM_044328962.1 323 202 91 199 192 NA NA NA NA NA NA 38288 XM_044309334.1 1 9 3 0 9 NA NA NA NA NA NA 38289 XM_044312570.1 0 0 8 0 53 NA NA NA NA NA NA 38290 XM_029351538.2 913 487 585 654 796 P57052 1.04e-26 Splicing regulator RBM11 (RNA-binding motif protein 11) Homo sapiens (Human) cell differentiation [GO:0030154]; cellular response to oxidative stress [GO:0034599]; mRNA processing [GO:0006397]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380] GO:0000381; GO:0003727; GO:0005634; GO:0005654; GO:0006397; GO:0008266; GO:0008380; GO:0016607; GO:0030154; GO:0034599; GO:0042803 38291 XM_029339267.2 0 36 0 101 19 Q9N2B7 3.78e-39 5-hydroxytryptamine receptor 1B (5-HT-1B) (5-HT1B) (Serotonin receptor 1B) Gorilla gorilla gorilla (Western lowland gorilla) adenylate cyclase-inhibiting serotonin receptor signaling pathway [GO:0007198]; behavior [GO:0007610]; bone remodeling [GO:0046849]; cellular response to alkaloid [GO:0071312]; cellular response to xenobiotic stimulus [GO:0071466]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; negative regulation of serotonin secretion [GO:0014063]; regulation of behavior [GO:0050795]; vasoconstriction [GO:0042310] GO:0004993; GO:0005886; GO:0007187; GO:0007198; GO:0007268; GO:0007610; GO:0014063; GO:0030425; GO:0030594; GO:0042310; GO:0045202; GO:0046849; GO:0050795; GO:0051378; GO:0071312; GO:0071466 38292 XR_006394804.1 84 0 0 0 108 NA NA NA NA NA NA 38293 XR_006391316.1 137 106 59 202 324 NA NA NA NA NA NA 38294 XM_044317535.1 1 0 15 31 5 NA NA NA NA NA NA 38295 XR_006397593.1 0 47 93 0 4 NA NA NA NA NA NA 38296 XM_044315719.1 95 38 19 225 154 Q8NCC3 2.32e-104 Phospholipase A2 group XV (1-O-acylceramide synthase) (ACS) (LCAT-like lysophospholipase) (LLPL) (EC 3.1.1.5) (Lysophospholipase 3) (Lysosomal phospholipase A and acyltransferase) (EC 2.3.1.-, EC 3.1.1.32, EC 3.1.1.4) (Lysosomal phospholipase A2) (LPLA2) Homo sapiens (Human) ceramide metabolic process [GO:0006672]; diacylglycerol biosynthetic process [GO:0006651]; fatty acid catabolic process [GO:0009062]; glycerophospholipid metabolic process [GO:0006650]; lipid metabolic process [GO:0006629]; phosphatidylcholine catabolic process [GO:0034638]; phosphatidylcholine metabolic process [GO:0046470]; phosphatidylethanolamine catabolic process [GO:0046338]; phosphatidylglycerol metabolic process [GO:0046471]; phosphatidylserine metabolic process [GO:0006658]; phospholipid metabolic process [GO:0006644] GO:0004622; GO:0005543; GO:0005576; GO:0005615; GO:0005654; GO:0005764; GO:0006629; GO:0006644; GO:0006650; GO:0006651; GO:0006658; GO:0006672; GO:0008270; GO:0008374; GO:0008970; GO:0009062; GO:0016020; GO:0016411; GO:0034638; GO:0043231; GO:0046338; GO:0046470; GO:0046471; GO:0047499; GO:0052739; GO:0052740; GO:0070062; GO:0102545 38297 XR_006393919.1 41 2 25 5 151 NA NA NA NA NA NA 38298 XM_044328373.1 0 0 0 0 60 Q28DX0 1.07e-81 Queuine tRNA-ribosyltransferase accessory subunit 2 (Queuine tRNA-ribosyltransferase domain-containing protein 1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) tRNA-guanine transglycosylation [GO:0101030] GO:0005737; GO:0005739; GO:0005741; GO:0008479; GO:0042803; GO:0046872; GO:0046982; GO:0101030 38299 XM_044316383.1 2758 1864 678 75 2445 Q9VW71 8.93e-25 Fat-like cadherin-related tumor suppressor homolog (Protein kugelei) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; centripetally migrating follicle cell migration [GO:0060269]; defense response to Gram-negative bacterium [GO:0050829]; establishment of planar polarity of follicular epithelium [GO:0042247]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; foregut morphogenesis [GO:0007440]; growth of a germarium-derived egg chamber [GO:0007295]; hindgut morphogenesis [GO:0007442]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of innate immune response [GO:0045089]; protein localization to cell leading edge [GO:1902463]; salivary gland development [GO:0007431] GO:0005509; GO:0005886; GO:0005925; GO:0007156; GO:0007295; GO:0007424; GO:0007431; GO:0007440; GO:0007442; GO:0009925; GO:0016339; GO:0030950; GO:0031254; GO:0042247; GO:0044331; GO:0044877; GO:0045089; GO:0048477; GO:0050829; GO:0050839; GO:0051491; GO:0060269; GO:0098609; GO:0098858; GO:1902463 38300 XR_006394078.1 224 227 190 56 64 NA NA NA NA NA NA 38301 XR_006393897.1 41 2 25 5 151 NA NA NA NA NA NA 38302 XM_044324779.1 7 0 2 34 10 NA NA NA NA NA NA 38303 XM_029350633.2 2930 1717 1235 2725 3504 Q9BUJ2 3.64e-127 Heterogeneous nuclear ribonucleoprotein U-like protein 1 (Adenovirus early region 1B-associated protein 5) (E1B-55 kDa-associated protein 5) (E1B-AP5) Homo sapiens (Human) response to virus [GO:0009615]; RNA processing [GO:0006396] GO:0003723; GO:0005634; GO:0005654; GO:0006396; GO:0009615; GO:0019899; GO:0045202; GO:1990904 38304 XM_044322642.1 450 598 393 356 372 NA NA NA NA NA NA 38305 XM_029337621.2 420 226 271 363 241 P97390 0 Vacuolar protein sorting-associated protein 45 (mVps45) Mus musculus (Mouse) intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0005794; GO:0006886; GO:0008021; GO:0010008; GO:0016020; GO:0016192 38306 XM_044309459.1 42762 20615 8731 11908 11621 NA NA NA NA NA NA 38307 XM_044309879.1 0 16 2 5 0 NA NA NA NA NA NA 38308 XM_044315685.1 0 0 0 0 24 NA NA NA NA NA NA 38309 XM_044319410.1 0 25 6 36 10 NA NA NA NA NA NA 38310 XM_029329621.2 98 6 48 89 141 O62809 1.83e-21 Orexin receptor type 2 (Ox-2-R) (Ox2-R) (Ox2R) (Hypocretin receptor type 2) Sus scrofa (Pig) circadian sleep/wake cycle process [GO:0022410]; feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; locomotion [GO:0040011]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; regulation of circadian sleep/wake cycle, wakefulness [GO:0010840]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0004930; GO:0005886; GO:0007186; GO:0007200; GO:0007218; GO:0007631; GO:0010840; GO:0016499; GO:0022410; GO:0040011; GO:0051480 38311 XR_006395912.1 22 0 0 0 1 NA NA NA NA NA NA 38312 XM_029344526.2 0 0 83 0 0 Q568G4 3.41e-31 EF-hand calcium-binding domain-containing protein 11 Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005509 38313 XR_006395925.1 85 67 96 63 80 NA NA NA NA NA NA 38314 XR_006394402.1 0 21 14 4 17 A5PK19 7.28e-130 eEF1A lysine and N-terminal methyltransferase (eEF1A-KNMT) (Methyltransferase-like protein 13) [Includes: eEF1A lysine methyltransferase (EC 2.1.1.-); eEF1A N-terminal methyltransferase (EC 2.1.1.-)] Bos taurus (Bovine) negative regulation of cell cycle G1/S phase transition [GO:1902807]; negative regulation of transcription by RNA polymerase II [GO:0000122] GO:0000122; GO:0005634; GO:0005737; GO:0005739; GO:0016279; GO:1902807 38315 XM_044326441.1 5 0 7 22 4 NA NA NA NA NA NA 38316 XM_044308356.1 4979 4534 2094 2406 1950 Q8BYK4 5.41e-88 Retinol dehydrogenase 12 (EC 1.1.1.300) Mus musculus (Mouse) cellular detoxification of aldehyde [GO:0110095]; retinol metabolic process [GO:0042572]; visual perception [GO:0007601] GO:0001917; GO:0004745; GO:0007601; GO:0042572; GO:0052650; GO:0102354; GO:0110095 38317 XM_029337637.2 37 0 0 41 0 Q5YCC5 5.68e-86 Transmembrane channel-like protein 7 Gallus gallus (Chicken) NA GO:0005886; GO:0008381 38318 XM_029351879.2 890 455 526 1262 538 P14629 1.14e-85 DNA excision repair protein ERCC-5 homolog (EC 3.1.-.-) (DNA repair protein complementing XP-G cells homolog) (Xeroderma pigmentosum group G-complementing protein homolog) Xenopus laevis (African clawed frog) nucleotide-excision repair [GO:0006289] GO:0003697; GO:0004519; GO:0005634; GO:0005694; GO:0006289; GO:0046872 38319 XM_029351879.2 890 455 526 1262 538 P14629 8.75e-59 DNA excision repair protein ERCC-5 homolog (EC 3.1.-.-) (DNA repair protein complementing XP-G cells homolog) (Xeroderma pigmentosum group G-complementing protein homolog) Xenopus laevis (African clawed frog) nucleotide-excision repair [GO:0006289] GO:0003697; GO:0004519; GO:0005634; GO:0005694; GO:0006289; GO:0046872 38320 XR_006393112.1 270 115 233 221 310 NA NA NA NA NA NA 38321 XR_003824812.2 346 526 342 306 298 NA NA NA NA NA NA 38322 XM_029348783.2 269 229 119 259 461 Q8BIK4 0 Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin-1) (Zizimin-1) Mus musculus (Mouse) positive regulation of GTPase activity [GO:0043547]; small GTPase mediated signal transduction [GO:0007264] GO:0005085; GO:0007264; GO:0012505; GO:0016020; GO:0031267; GO:0043547 38323 XR_006394116.1 72 9 63 23 73 NA NA NA NA NA NA 38324 XR_006397749.1 127 52 106 75 125 NA NA NA NA NA NA 38325 XM_029337641.2 389 292 188 471 297 NA NA NA NA NA NA 38326 XM_044321411.1 290 267 268 340 42 J7GQ11 2.12e-76 L-tyrosine decarboxylase (TDC) (EC 4.1.1.25) Levilactobacillus brevis (Lactobacillus brevis) carboxylic acid metabolic process [GO:0019752] GO:0004837; GO:0019752; GO:0030170; GO:0036468 38327 XM_029326743.2 0 0 0 0 7 Q15760 1.61e-32 Probable G-protein coupled receptor 19 (GPR-NGA) Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0005886; GO:0005929; GO:0007186 38328 XM_044308726.1 113 52 97 226 224 NA NA NA NA NA NA 38329 XM_044327630.1 17 0 0 0 588 NA NA NA NA NA NA 38330 XM_044323183.1 52 16 37 61 86 Q13591 4.96e-71 Semaphorin-5A (Semaphorin-F) (Sema F) Homo sapiens (Human) axon extension [GO:0048675]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell-cell signaling [GO:0007267]; diencephalon development [GO:0021536]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of cell adhesion [GO:0007162]; negative regulation of endothelial cell apoptotic process [GO:2000352]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; positive chemotaxis [GO:0050918]; positive regulation of actin filament depolymerization [GO:0030836]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein kinase B signaling [GO:0051897]; semaphorin-plexin signaling pathway [GO:0071526]; signal clustering [GO:1990256] GO:0001755; GO:0001938; GO:0002043; GO:0005886; GO:0007155; GO:0007162; GO:0007267; GO:0007399; GO:0007411; GO:0007413; GO:0016020; GO:0021536; GO:0030215; GO:0030335; GO:0030836; GO:0035373; GO:0043395; GO:0045499; GO:0045545; GO:0045766; GO:0048675; GO:0048842; GO:0048843; GO:0050918; GO:0051897; GO:0060326; GO:0070062; GO:0071526; GO:0090263; GO:1990256; GO:2000352; GO:2001028 38331 XM_044315878.1 0 40 7 0 25 NA NA NA NA NA NA 38332 XM_029334477.2 7592 5750 3841 5768 6023 Q8R4G6 9.66e-179 Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (EC 2.4.1.155) (Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase) (GlcNAc-T V) (GNT-V) (Mannoside acetylglucosaminyltransferase 5) (N-acetylglucosaminyl-transferase V) [Cleaved into: Secreted alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (Secreted beta-1,6-N-acetylglucosaminyltransferase V) (Secreted GNT-V)] Mus musculus (Mouse) negative regulation of protein tyrosine phosphatase activity [GO:1903614]; positive regulation of cell migration [GO:0030335]; positive regulation of receptor signaling pathway via STAT [GO:1904894]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279] GO:0000139; GO:0004864; GO:0005576; GO:0005794; GO:0006487; GO:0008375; GO:0016020; GO:0016757; GO:0018279; GO:0030144; GO:0030145; GO:0030335; GO:0043204; GO:1903614; GO:1904894 38333 XM_029334477.2 7592 5750 3841 5768 6023 Q8R4G6 2.46e-29 Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (EC 2.4.1.155) (Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase) (GlcNAc-T V) (GNT-V) (Mannoside acetylglucosaminyltransferase 5) (N-acetylglucosaminyl-transferase V) [Cleaved into: Secreted alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (Secreted beta-1,6-N-acetylglucosaminyltransferase V) (Secreted GNT-V)] Mus musculus (Mouse) negative regulation of protein tyrosine phosphatase activity [GO:1903614]; positive regulation of cell migration [GO:0030335]; positive regulation of receptor signaling pathway via STAT [GO:1904894]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279] GO:0000139; GO:0004864; GO:0005576; GO:0005794; GO:0006487; GO:0008375; GO:0016020; GO:0016757; GO:0018279; GO:0030144; GO:0030145; GO:0030335; GO:0043204; GO:1903614; GO:1904894 38334 XM_044323107.1 12 0 0 0 8 NA NA NA NA NA NA 38335 XM_044324271.1 617 0 14 23 10 NA NA NA NA NA NA 38336 XM_029331402.2 5986 6359 3845 4003 3465 NA NA NA NA NA NA 38337 XM_029349000.2 75 4 41 68 99 NA NA NA NA NA NA 38338 XM_044307995.1 30 3 4 12 5 NA NA NA NA NA NA 38339 XM_044327095.1 2274 2519 1405 1578 1760 Q5RCP3 6.52e-48 U6 snRNA-associated Sm-like protein LSm8 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0003723; GO:0005634; GO:0005688; GO:0046540; GO:0071005; GO:0120115 38340 XM_029334893.2 385 224 229 272 277 NA NA NA NA NA NA 38341 XM_029336105.2 23295 34989 8012 28301 30101 NA NA NA NA NA NA 38342 XM_029336132.2 2268 2311 1339 2248 2688 O55125 4.39e-90 Protein NipSnap homolog 1 (NipSnap1) Mus musculus (Mouse) sensory perception of pain [GO:0019233] GO:0005739; GO:0005743; GO:0016020; GO:0019233; GO:0042165; GO:0097060 38343 XM_044318291.1 45 12 4 33 5 NA NA NA NA NA NA 38344 XM_029334086.2 88 340 181 60 0 Q09081 1.61e-144 Potassium voltage-gated channel subfamily A member 2 (KC22) (Voltage-gated potassium channel subunit Kv1.2) Oryctolagus cuniculus (Rabbit) neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233] GO:0005249; GO:0005251; GO:0005789; GO:0005886; GO:0008076; GO:0014059; GO:0019228; GO:0019233; GO:0021633; GO:0030027; GO:0030424; GO:0030425; GO:0031258; GO:0032809; GO:0033010; GO:0034765; GO:0042734; GO:0043194; GO:0043204; GO:0043679; GO:0044224; GO:0045188; GO:0051260; GO:0071805 38345 XM_044311207.1 26 29 39 17 5 Q9FT72 1.12e-21 ATP-dependent DNA helicase Q-like 3 (EC 3.6.4.12) (RecQ-like protein 3) (AtRecQ3) (AtRecQl3) Arabidopsis thaliana (Mouse-ear cress) DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724] GO:0000724; GO:0004386; GO:0005524; GO:0005634; GO:0005694; GO:0005737; GO:0006268; GO:0006281; GO:0006310; GO:0009378; GO:0016887; GO:0032508; GO:0043138; GO:0046872; GO:1990814 38346 XM_044312540.1 15 9 104 5 82 NA NA NA NA NA NA 38347 XM_029339057.2 209 180 87 134 150 P58557 2.83e-22 Endoribonuclease YbeY (EC 3.1.-.-) Homo sapiens (Human) rRNA processing [GO:0006364] GO:0004222; GO:0004521; GO:0005634; GO:0006364; GO:0046872 38348 XM_044326297.1 28 8 21 24 31 P02469 1.83e-133 Laminin subunit beta-1 (Laminin B1 chain) (Laminin-1 subunit beta) (Laminin-10 subunit beta) (Laminin-12 subunit beta) (Laminin-2 subunit beta) (Laminin-6 subunit beta) (Laminin-8 subunit beta) Mus musculus (Mouse) animal organ morphogenesis [GO:0009887]; basement membrane assembly [GO:0070831]; cell migration [GO:0016477]; embryo implantation [GO:0007566]; learning or memory [GO:0007611]; negative regulation of cell adhesion [GO:0007162]; neuron projection development [GO:0031175]; neuronal-glial interaction involved in cerebral cortex radial glia guided migration [GO:0021812]; odontogenesis [GO:0042476]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of muscle cell differentiation [GO:0051149]; regulation of basement membrane organization [GO:0110011]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888] GO:0005178; GO:0005201; GO:0005576; GO:0005604; GO:0005606; GO:0005607; GO:0005615; GO:0005634; GO:0007162; GO:0007566; GO:0007611; GO:0009887; GO:0009888; GO:0016477; GO:0019899; GO:0021812; GO:0030335; GO:0031012; GO:0031175; GO:0034446; GO:0042476; GO:0043208; GO:0043256; GO:0043257; GO:0043259; GO:0045785; GO:0048471; GO:0051149; GO:0062023; GO:0070831; GO:0098637; GO:0110011; GO:2001046 38349 XM_044327358.1 1 0 0 0 8 NA NA NA NA NA NA 38350 XR_006394361.1 18 7 8 4 17 NA NA NA NA NA NA 38351 XM_044316305.1 0 1 0 3 9 Q5SVZ6 1.41e-22 Zinc finger MYM-type protein 1 Homo sapiens (Human) NA GO:0005634; GO:0008270; GO:0046983 38352 XM_029327327.2 0 1 0 0 10 NA NA NA NA NA NA 38353 XM_029325439.2 0 0 0 0 29 Q9HF54 7.38e-41 GTP-binding protein RHO1 Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii) actin filament organization [GO:0007015]; cortical cytoskeleton organization [GO:0030865]; establishment or maintenance of cell polarity [GO:0007163]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; small GTPase mediated signal transduction [GO:0007264] GO:0003924; GO:0005525; GO:0005856; GO:0005886; GO:0005938; GO:0007015; GO:0007163; GO:0007264; GO:0008360; GO:0019901; GO:0030865; GO:0031410; GO:0032956; GO:0042995 38354 XM_044324037.1 298616 424298 334764 220534 186494 P42577 1.79e-65 Soma ferritin (EC 1.16.3.1) Lymnaea stagnalis (Great pond snail) (Helix stagnalis) cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826] GO:0004322; GO:0005737; GO:0006826; GO:0006879; GO:0008199 38355 XM_044324037.1 298616 424298 334764 220534 186494 P42577 4.39e-42 Soma ferritin (EC 1.16.3.1) Lymnaea stagnalis (Great pond snail) (Helix stagnalis) cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826] GO:0004322; GO:0005737; GO:0006826; GO:0006879; GO:0008199 38356 XM_029326316.2 84 90 70 73 92 A0A2B4RNI3 6.79e-25 NA NA NA NA 38357 XM_029355471.2 2131 1265 1126 1954 1588 Q07722 2.68e-180 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 (EC 3.1.4.11) (PCL-C1) (Phosphoinositide phospholipase C-beta-4) (Phospholipase C-beta-4) (PLC-beta-4) Bos taurus (Bovine) lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015] GO:0004435; GO:0005509; GO:0016042; GO:0048015; GO:0110165 38358 XM_029355471.2 2131 1265 1126 1954 1588 Q07722 1.25e-108 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 (EC 3.1.4.11) (PCL-C1) (Phosphoinositide phospholipase C-beta-4) (Phospholipase C-beta-4) (PLC-beta-4) Bos taurus (Bovine) lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015] GO:0004435; GO:0005509; GO:0016042; GO:0048015; GO:0110165 38359 XM_029337257.2 143 117 0 38 75 F4KFT7 3.43e-23 Bifunctional TH2 protein, mitochondrial (THIAMINE REQUIRING 2) [Includes: Thiamine phosphate phosphatase (EC 3.1.3.100); Aminopyrimidine aminohydrolase (EC 3.5.99.2)] Arabidopsis thaliana (Mouse-ear cress) thiamine biosynthetic process [GO:0009228] GO:0005739; GO:0005829; GO:0009228; GO:0042131; GO:0050334 38360 XM_029326952.2 48 321 109 233 287 NA NA NA NA NA NA 38361 XM_044315809.1 22 49 68 39518 15307 NA NA NA NA NA NA 38362 XM_044311527.1 0 0 43 55 0 Q7RTR2 6.27e-26 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 38363 XM_044311527.1 0 0 43 55 0 Q7RTR2 1.82e-25 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 38364 XM_044311527.1 0 0 43 55 0 Q7RTR2 2.47e-24 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 38365 XM_044311527.1 0 0 43 55 0 Q7RTR2 2.98e-23 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 38366 XM_044311527.1 0 0 43 55 0 Q7RTR2 7.04e-23 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 38367 XM_044307657.1 29 227 24 73 164 NA NA NA NA NA NA 38368 XM_029337693.2 8 20 41 0 80 NA NA NA NA NA NA 38369 XM_029337672.2 42 11 32 13 127 NA NA NA NA NA NA 38370 XM_029345964.2 32 18 17 0 46 P26794 2.28e-49 Serine/threonine-protein kinase pim-1 (EC 2.7.11.1) Rattus norvegicus (Rat) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cellular detoxification [GO:1990748]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cardioblast proliferation [GO:1905062]; positive regulation of DNA-templated transcription [GO:0045893]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of transmembrane transporter activity [GO:0022898]; vitamin D receptor signaling pathway [GO:0070561] GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0005886; GO:0006468; GO:0006915; GO:0007049; GO:0022898; GO:0030145; GO:0043024; GO:0043066; GO:0043433; GO:0045893; GO:0046777; GO:0050821; GO:0060045; GO:0070561; GO:0090336; GO:0106310; GO:1902033; GO:1905062; GO:1990748 38371 XR_006393644.1 36533 288955 274888 155334 163547 NA NA NA NA NA NA 38372 XM_044324405.1 0 298 49 643 1034 P35658 9.05e-78 Nuclear pore complex protein Nup214 (214 kDa nucleoporin) (Nucleoporin Nup214) (Protein CAN) Homo sapiens (Human) mitotic cell cycle [GO:0000278]; mRNA export from nucleus [GO:0006406]; nucleocytoplasmic transport [GO:0006913]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; regulation of cell cycle [GO:0051726]; regulation of nucleocytoplasmic transport [GO:0046822]; RNA export from nucleus [GO:0006405] GO:0000278; GO:0005049; GO:0005635; GO:0005643; GO:0005654; GO:0005829; GO:0006405; GO:0006406; GO:0006606; GO:0006611; GO:0006913; GO:0008139; GO:0017056; GO:0046822; GO:0051726; GO:1990876 38373 XM_044324405.1 0 298 49 643 1034 P35658 1.09e-32 Nuclear pore complex protein Nup214 (214 kDa nucleoporin) (Nucleoporin Nup214) (Protein CAN) Homo sapiens (Human) mitotic cell cycle [GO:0000278]; mRNA export from nucleus [GO:0006406]; nucleocytoplasmic transport [GO:0006913]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; regulation of cell cycle [GO:0051726]; regulation of nucleocytoplasmic transport [GO:0046822]; RNA export from nucleus [GO:0006405] GO:0000278; GO:0005049; GO:0005635; GO:0005643; GO:0005654; GO:0005829; GO:0006405; GO:0006406; GO:0006606; GO:0006611; GO:0006913; GO:0008139; GO:0017056; GO:0046822; GO:0051726; GO:1990876 38374 XM_029348781.2 58 153 81 80 149 NA NA NA NA NA NA 38375 XM_029342930.2 4046 6549 2440 4562 3088 P31399 6.19e-26 ATP synthase subunit d, mitochondrial (ATPase subunit d) (ATP synthase peripheral stalk subunit d) Rattus norvegicus (Rat) ATP metabolic process [GO:0046034]; cellular response to peptide [GO:1901653]; proton motive force-driven ATP synthesis [GO:0015986]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776] GO:0000274; GO:0000276; GO:0005739; GO:0005743; GO:0005753; GO:0015078; GO:0015986; GO:0042776; GO:0044877; GO:0046034; GO:1901653 38376 XR_003827566.2 8 1046 10 7 501 NA NA NA NA NA NA 38377 XM_044315508.1 50 34 18 10 120 NA NA NA NA NA NA 38378 XR_006393889.1 17 35 0 20 33 NA NA NA NA NA NA 38379 XR_006397137.1 90 44 93 86 215 NA NA NA NA NA NA 38380 XR_006395341.1 56 18 28 4 10 O42430 8.02e-86 Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) Limanda limanda (Common dab) (Pleuronectes limanda) NA GO:0005506; GO:0005789; GO:0020037; GO:0070330 38381 XM_029346832.2 426 469 295 675 490 Q5RFE6 6.5e-157 Threonine synthase-like 2 (TSH2) (EC 4.2.3.-) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0016829 38382 XM_029347868.2 0 6 36 36 12 NA NA NA NA NA NA 38383 XR_006392113.1 78 163 118 192 141 NA NA NA NA NA NA 38384 XR_006393331.1 97 52 118 20 378 B3EWZ9 0 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 38385 XR_006393331.1 97 52 118 20 378 B3EWZ9 0 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 38386 XR_006393331.1 97 52 118 20 378 B3EWZ9 0 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 38387 XR_006393331.1 97 52 118 20 378 B3EWZ9 5.34e-173 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 38388 XR_006393331.1 97 52 118 20 378 B3EWZ9 2.3e-76 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 38389 XR_006393331.1 97 52 118 20 378 B3EWZ9 2.3e-76 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 38390 XR_006393331.1 97 52 118 20 378 B3EWZ9 2.95e-70 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 38391 XR_006393331.1 97 52 118 20 378 B3EWZ9 2.95e-70 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 38392 XM_044329331.1 324 127 195 231 424 Q7TN88 7e-67 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 38393 XM_044329331.1 324 127 195 231 424 Q7TN88 5.94e-52 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 38394 XM_044314124.1 8 0 0 0 5 NA NA NA NA NA NA 38395 XM_029345405.2 0 25 0 0 0 Q9CYL5 4.11e-23 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Mus musculus (Mouse) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070374 38396 XM_029351645.2 34 9 14 11 70 NA NA NA NA NA NA 38397 XM_029351675.2 613 364 530 735 561 NA NA NA NA NA NA 38398 XM_029355605.2 729 661 333 654 708 Q62825 0 Exocyst complex component 3 (Exocyst complex component Sec6) (rSec6) Rattus norvegicus (Rat) exocyst localization [GO:0051601]; exocytosis [GO:0006887]; protein transport [GO:0015031] GO:0000145; GO:0000149; GO:0005794; GO:0006887; GO:0015031; GO:0016020; GO:0030426; GO:0030496; GO:0042734; GO:0048471; GO:0051601 38399 XM_029343461.2 11 34 0 0 0 NA NA NA NA NA NA 38400 XM_029351541.2 0 0 0 0 7 Q05090 0 Kinesin light chain (KLC) Strongylocentrotus purpuratus (Purple sea urchin) microtubule-based movement [GO:0007018] GO:0005737; GO:0005871; GO:0005874; GO:0007018; GO:0019894 38401 XM_029338588.2 0 4 0 5 7 NA NA NA NA NA NA 38402 XR_006392595.1 4 23 24 10 30 NA NA NA NA NA NA 38403 XM_044314273.1 0 5 0 1 11 NA NA NA NA NA NA 38404 XM_044312867.1 26 23 27 3 44 Q7ZU90 7.4e-152 Chromodomain-helicase-DNA-binding protein 1-like (EC 3.6.4.-) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to DNA damage stimulus [GO:0006974]; chromatin remodeling [GO:0006338]; DNA repair [GO:0006281] GO:0000166; GO:0003678; GO:0005524; GO:0005634; GO:0006281; GO:0006338; GO:0006974; GO:0016887; GO:0031491; GO:0035861; GO:0140566; GO:0140658; GO:0160004 38405 XM_044312088.1 19 0 0 0 0 Q99MW1 5.62e-30 Serine/threonine-protein kinase 31 (EC 2.7.11.1) Mus musculus (Mouse) protein phosphorylation [GO:0006468] GO:0001669; GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0006468; GO:0106310 38406 XR_006395718.1 0 0 0 3 7 NA NA NA NA NA NA 38407 XR_006393487.1 27 32 3 25 5 NA NA NA NA NA NA 38408 XM_044315897.1 0 0 0 5 8 Q9VBW3 6.39e-58 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 38409 XM_044316912.1 496 394 220 300 347 Q5RA37 2.86e-45 Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 (EC 3.1.3.16) (RNA polymerase II-associated protein 2) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) dephosphorylation of RNA polymerase II C-terminal domain [GO:0070940]; snRNA transcription [GO:0009301] GO:0005634; GO:0005737; GO:0008420; GO:0009301; GO:0016591; GO:0017018; GO:0043175; GO:0046872; GO:0070940 38410 XR_006395939.1 0 7 0 2 0 NA NA NA NA NA NA 38411 XR_006397960.1 42 55 50 14 5 NA NA NA NA NA NA 38412 XM_029339160.2 646 489 483 893 562 NA NA NA NA NA NA 38413 XM_029348471.2 0 0 0 0 45 NA NA NA NA NA NA 38414 XM_029344451.2 137 89 29 92 76 Q8N865 1.75e-39 Uncharacterized protein C7orf31 Homo sapiens (Human) NA GO:0005737; GO:0005813 38415 XM_029323860.2 40 11 13 38 126 Q566X8 2.32e-23 Diencephalon/mesencephalon homeobox protein 1-B Danio rerio (Zebrafish) (Brachydanio rerio) midbrain development [GO:0030901]; regulation of cell cycle [GO:0051726]; regulation of mitotic cell cycle [GO:0007346]; regulation of neural retina development [GO:0061074]; regulation of neurogenesis [GO:0050767]; regulation of transcription by RNA polymerase II [GO:0006357]; retina development in camera-type eye [GO:0060041] GO:0000977; GO:0000981; GO:0005634; GO:0006357; GO:0007346; GO:0030901; GO:0050767; GO:0051726; GO:0060041; GO:0061074 38416 XR_003822760.2 9 0 0 7 0 NA NA NA NA NA NA 38417 XR_006391419.1 4 2 22 0 77 NA NA NA NA NA NA 38418 XR_006398110.1 20 21 2 0 19 NA NA NA NA NA NA 38419 XR_003823986.2 3 4 10 4 2 NA NA NA NA NA NA 38420 XM_044318105.1 10 10 4 17 20 NA NA NA NA NA NA 38421 XM_029330752.2 253 272 129 219 275 Q5U4I3 1.12e-66 Cyclin-D1-binding protein 1 homolog Xenopus laevis (African clawed frog) cell cycle [GO:0007049]; regulation of cell cycle [GO:0051726] GO:0005634; GO:0005737; GO:0007049; GO:0051726 38422 XM_029346834.2 18 1 23 6 111 P00565 0 Creatine kinase M-type (EC 2.7.3.2) (Creatine kinase M chain) (Creatine phosphokinase M-type) (CPK-M) (M-CK) Gallus gallus (Chicken) phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]; response to heat [GO:0009408] GO:0004111; GO:0005524; GO:0005615; GO:0005829; GO:0009408; GO:0016301; GO:0016310; GO:0046314 38423 XM_044327186.1 341 159 399 371 444 NA NA NA NA NA NA 38424 XM_044325433.1 351 215 213 347 217 NA NA NA NA NA NA 38425 XM_029330457.2 1217 1303 822 1142 1119 Q5W111 8.16e-66 SPRY domain-containing protein 7 (Chronic lymphocytic leukemia deletion region gene 6 protein) (CLL deletion region gene 6 protein) Homo sapiens (Human) NA NA 38426 XM_029326522.2 0 3 25 8 13 Q9V6Y3 9.19e-31 Probable 28S ribosomal protein S16, mitochondrial (MRP-S16) (S16mt) Drosophila melanogaster (Fruit fly) mitochondrial translation [GO:0032543] GO:0003735; GO:0005763; GO:0015935; GO:0032543 38427 XR_003828595.2 51 27 24 20 185 NA NA NA NA NA NA 38428 XR_006393292.1 26 7 8 35 0 NA NA NA NA NA NA 38429 XM_044320396.1 363 196 142 619 333 NA NA NA NA NA NA 38430 XM_044309583.1 0 0 0 0 14 NA NA NA NA NA NA 38431 XM_029340698.2 3477 3636 1245 3613 1490 Q9Y4L5 7.93e-45 E3 ubiquitin-protein ligase RNF115 (EC 2.3.2.27) (RING finger protein 115) (RING-type E3 ubiquitin transferase RNF115) (Rab7-interacting RING finger protein) (Rabring 7) (Zinc finger protein 364) Homo sapiens (Human) negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] GO:0004842; GO:0005829; GO:0042059; GO:0043162; GO:0046872; GO:0051865; GO:0061630; GO:0070534; GO:0070936 38432 XM_029355487.2 5331 3955 2994 4040 3576 Q5NVP8 2.54e-44 Protein lin-52 homolog Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) regulation of DNA-templated transcription [GO:0006355] GO:0006355; GO:0070176 38433 XM_044307510.1 73 81 42 66 126 NA NA NA NA NA NA 38434 XM_029329441.2 592 416 373 537 342 D3ZAT9 2.4e-52 Failed axon connections homolog Rattus norvegicus (Rat) NA GO:0005737; GO:0016020 38435 XR_006392680.1 14 8 39 2 3 NA NA NA NA NA NA 38436 XM_044323775.1 11 1 0 0 4 NA NA NA NA NA NA 38437 XM_029336897.2 15 0 0 0 0 NA NA NA NA NA NA 38438 XM_044319658.1 17 20 6 39 3 NA NA NA NA NA NA 38439 XM_044311265.1 112 0 183 0 776 Q9VBW3 7.08e-45 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 38440 XM_044306932.1 130 70 33 93 173 Q61382 8.54e-51 TNF receptor-associated factor 4 (EC 2.3.2.27) (Cysteine-rich motif associated to RING and Traf domains protein 1) Mus musculus (Mouse) activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; innate immune response [GO:0045087]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein kinase activity [GO:0045860]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; respiratory gaseous exchange by respiratory system [GO:0007585]; respiratory tube development [GO:0030323] GO:0001650; GO:0005164; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0005923; GO:0006915; GO:0007250; GO:0007585; GO:0008270; GO:0016740; GO:0019901; GO:0030323; GO:0031625; GO:0031996; GO:0042802; GO:0042981; GO:0043122; GO:0043161; GO:0045087; GO:0045860; GO:0046330; GO:0048471; GO:0050699 38441 XM_029343426.2 64 41 80 97 136 Q6TEN1 1.55e-34 Ras-related protein Rap-1b (EC 3.6.5.2) Danio rerio (Zebrafish) (Brachydanio rerio) cartilage morphogenesis [GO:0060536]; cellular response to cAMP [GO:0071320]; chondrocyte intercalation involved in growth plate cartilage morphogenesis [GO:0003428]; convergent extension [GO:0060026]; heart development [GO:0007507]; negative regulation of synaptic vesicle exocytosis [GO:2000301]; Rap protein signal transduction [GO:0032486]; somite rostral/caudal axis specification [GO:0032525]; somitogenesis [GO:0001756] GO:0001756; GO:0003428; GO:0003924; GO:0003925; GO:0004708; GO:0005525; GO:0005829; GO:0005886; GO:0005911; GO:0007507; GO:0019003; GO:0032486; GO:0032525; GO:0060026; GO:0060536; GO:0071320; GO:2000301 38442 XM_029339001.2 0 21 22 0 40 NA NA NA NA NA NA 38443 XM_044316734.1 156 293 295 121 419 NA NA NA NA NA NA 38444 XM_044307211.1 27 17 7 3 25 Q94K49 1.41e-26 Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1 (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) epigenetic regulation of gene expression [GO:0040029] GO:0003682; GO:0004518; GO:0005634; GO:0035098; GO:0035102; GO:0040029; GO:0046872 38445 XM_029348112.2 21 62 98 191 48 NA NA NA NA NA NA 38446 XR_006397391.1 315 143 124 6 445 NA NA NA NA NA NA 38447 XM_029324054.1 4151 5400 2704 6058 5802 Q6QLW4 9.47e-64 Cytochrome c Pectinaria gouldii (Trumpet worm) (Ice-cream cone worm) NA GO:0005758; GO:0009055; GO:0020037; GO:0046872; GO:0070469 38448 XM_029355687.2 3232 1569 786 5928 5339 Q0IH87 1.25e-54 Paired box protein Pax-3-B (xPax3-B) (Paired-domain transcription factor Pax3-B) Xenopus laevis (African clawed frog) fibroblast growth factor receptor signaling pathway [GO:0008543]; hatching gland development [GO:0048785]; nervous system development [GO:0007399]; neural crest cell fate commitment [GO:0014034]; neural crest formation [GO:0014029]; positive regulation of DNA-templated transcription [GO:0045893]; Wnt signaling pathway [GO:0016055] GO:0000981; GO:0003677; GO:0005634; GO:0007399; GO:0008543; GO:0014029; GO:0014034; GO:0016055; GO:0045893; GO:0048785 38449 XM_044320724.1 0 34 0 12 6 Q96DM1 3.67e-52 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 38450 XM_044325488.1 2 98 44 0 39 Q6DIV6 3.17e-47 Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Solute carrier family 32 member 1) (Vesicular GABA transporter) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) beta-alanine transport [GO:0001762]; gamma-aminobutyric acid import [GO:0051939]; gamma-aminobutyric acid transport [GO:0015812]; glycine transport [GO:0015816]; neurotransmitter transport [GO:0006836] GO:0001762; GO:0006836; GO:0008021; GO:0015185; GO:0015187; GO:0015812; GO:0015816; GO:0030659; GO:0042995; GO:0051939; GO:0098793; GO:0140799; GO:0140800 38451 XM_044315578.1 21 3 0 8 15 NA NA NA NA NA NA 38452 XM_044328759.1 153 146 107 32 142 NA NA NA NA NA NA 38453 XM_044325466.1 270 122 94 152 115 B1AVH7 5.69e-145 TBC1 domain family member 2A Mus musculus (Mouse) activation of GTPase activity [GO:0090630]; positive regulation of GTPase activity [GO:0043547] GO:0005096; GO:0005654; GO:0005829; GO:0005886; GO:0030054; GO:0031410; GO:0043547; GO:0045296; GO:0070161; GO:0090630 38454 XM_029330704.2 186 68 0 99 170 P29119 1.95e-120 Furin-1 (EC 3.4.21.75) (Dibasic-processing enzyme) (Paired basic amino acid residue-cleaving enzyme) (PACE) Xenopus laevis (African clawed frog) positive regulation of transforming growth factor beta1 activation [GO:1901394]; proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0005794; GO:0005886; GO:0006508; GO:0010008; GO:0046872; GO:1901394 38455 XM_029356825.2 30 39 20 37 18 NA NA NA NA NA NA 38456 XR_006394906.1 55 6 7 136 13 NA NA NA NA NA NA 38457 XM_029349035.2 197 33 138 165 322 NA NA NA NA NA NA 38458 XM_029330394.2 22 17 0 5 82 Q5JVF3 8.18e-166 PCI domain-containing protein 2 (CSN12-like protein) Homo sapiens (Human) heterochromatin organization [GO:0070828]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lymphoid progenitor cell differentiation [GO:1905457]; negative regulation of transcription initiation by RNA polymerase II [GO:0060633]; poly(A)+ mRNA export from nucleus [GO:0016973]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000973]; protein transport [GO:0015031]; regulation of mRNA stability [GO:0043488]; spleen development [GO:0048536]; transcription elongation by RNA polymerase II promoter [GO:0006368] GO:0000973; GO:0003690; GO:0003723; GO:0005634; GO:0005737; GO:0006368; GO:0015031; GO:0016973; GO:0043066; GO:0043488; GO:0044615; GO:0045579; GO:0045893; GO:0048536; GO:0060633; GO:0070390; GO:0070828; GO:0090267; GO:1905457; GO:2000117 38459 XM_029329818.2 2612 2375 1203 1473 1037 Q9Y5B8 2.17e-156 Nucleoside diphosphate kinase 7 (NDK 7) (NDP kinase 7) (EC 2.7.4.6) (nm23-H7) Homo sapiens (Human) CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside diphosphate phosphorylation [GO:0006165]; UTP biosynthetic process [GO:0006228] GO:0004550; GO:0005524; GO:0005813; GO:0005829; GO:0005879; GO:0006165; GO:0006183; GO:0006228; GO:0006241; GO:0046872 38460 XR_006391951.1 0 0 0 0 8 NA NA NA NA NA NA 38461 XR_006393796.1 29 34 56 30 35 NA NA NA NA NA NA 38462 XM_029336654.2 214 91 107 130 280 NA NA NA NA NA NA 38463 XR_003824815.2 1679 1171 911 1348 1132 A7SLC8 2.54e-72 N-acetyltransferase 9-like protein (EC 2.3.1.-) Nematostella vectensis (Starlet sea anemone) protein acetylation [GO:0006473] GO:0006473; GO:0008080 38464 XM_029329467.2 3150 2019 1870 3339 2226 P51464 0 Argininosuccinate lyase (ASAL) (EC 4.3.2.1) (Arginosuccinase) Lithobates catesbeianus (American bullfrog) (Rana catesbeiana) arginine biosynthetic process via ornithine [GO:0042450]; urea cycle [GO:0000050] GO:0000050; GO:0004056; GO:0042450 38465 XM_029325000.2 121 0 0 0 0 NA NA NA NA NA NA 38466 XR_006397977.1 1536 2038 1357 2488 1999 Q99743 3.46e-42 Neuronal PAS domain-containing protein 2 (Neuronal PAS2) (Basic-helix-loop-helix-PAS protein MOP4) (Class E basic helix-loop-helix protein 9) (bHLHe9) (Member of PAS protein 4) (PAS domain-containing protein 4) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; central nervous system development [GO:0007417]; circadian regulation of gene expression [GO:0032922]; negative regulation of cell death [GO:0060548]; positive regulation of behavioral fear response [GO:2000987]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of response to DNA damage stimulus [GO:2001020]; regulation of transcription by RNA polymerase II [GO:0006357]; response to redox state [GO:0051775]; response to xenobiotic stimulus [GO:0009410] GO:0000785; GO:0000978; GO:0000981; GO:0003677; GO:0003700; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0006974; GO:0007417; GO:0009410; GO:0032922; GO:0045739; GO:0045893; GO:0045944; GO:0046872; GO:0046983; GO:0051775; GO:0051879; GO:0060548; GO:1990513; GO:1990837; GO:2000987; GO:2001020 38467 XR_006393599.1 0 0 0 7 0 NA NA NA NA NA NA 38468 XR_003826729.2 1258 2412 739 1222 964 NA NA NA NA NA NA 38469 XM_044328663.1 48 56 3 19 83 Q8VIJ8 1.18e-162 GATOR complex protein NPRL3 (Nitrogen permease regulator 3-like protein) Mus musculus (Mouse) aorta morphogenesis [GO:0035909]; cardiac muscle tissue development [GO:0048738]; cellular response to amino acid starvation [GO:0034198]; negative regulation of TOR signaling [GO:0032007]; negative regulation of TORC1 signaling [GO:1904262]; positive regulation of autophagy [GO:0010508]; roof of mouth development [GO:0060021]; TORC1 signaling [GO:0038202]; ventricular septum development [GO:0003281] GO:0003281; GO:0005096; GO:0005765; GO:0010508; GO:0032007; GO:0034198; GO:0035909; GO:0038202; GO:0048738; GO:0060021; GO:1904262; GO:1990130 38470 XM_044314381.1 91 60 96 183 262 NA NA NA NA NA NA 38471 XM_044308871.1 8 0 10 44 4 NA NA NA NA NA NA 38472 XM_029353241.2 331 192 138 303 209 Q8IX29 4.93e-66 F-box only protein 16 Homo sapiens (Human) NA NA 38473 XR_006392686.1 0 0 11 0 27 NA NA NA NA NA NA 38474 XM_029327730.2 3 0 0 0 9 O60290 2.98e-69 Zinc finger protein 862 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006355; GO:0046872; GO:0046983 38475 XM_044329299.1 0 0 20 20 7 P08575 9.78e-36 Receptor-type tyrosine-protein phosphatase C (EC 3.1.3.48) (Leukocyte common antigen) (L-CA) (T200) (CD antigen CD45) Homo sapiens (Human) alpha-beta T cell proliferation [GO:0046633]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; B cell receptor signaling pathway [GO:0050853]; bone marrow development [GO:0048539]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell cycle phase transition [GO:0044770]; cell surface receptor signaling pathway [GO:0007166]; cellular response to extracellular stimulus [GO:0031668]; defense response to virus [GO:0051607]; dephosphorylation [GO:0016311]; DN2 thymocyte differentiation [GO:1904155]; extrinsic apoptotic signaling pathway [GO:0097191]; gamma-delta T cell differentiation [GO:0042492]; hematopoietic progenitor cell differentiation [GO:0002244]; heterotypic cell-cell adhesion [GO:0034113]; leukocyte cell-cell adhesion [GO:0007159]; MAPK cascade [GO:0000165]; natural killer cell differentiation [GO:0001779]; negative regulation of cell adhesion involved in substrate-bound cell migration [GO:0006933]; negative regulation of cytokine-mediated signaling pathway [GO:0001960]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of microglial cell activation [GO:1903979]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein tyrosine kinase activity [GO:0061099]; negative regulation of T cell mediated cytotoxicity [GO:0001915]; negative thymic T cell selection [GO:0045060]; peptidyl-tyrosine phosphorylation [GO:0018108]; plasma membrane raft distribution [GO:0044855]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of antigen receptor-mediated signaling pathway [GO:0050857]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis [GO:1905451]; positive regulation of gamma-delta T cell differentiation [GO:0045588]; positive regulation of hematopoietic stem cell migration [GO:2000473]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein tyrosine phosphatase activity [GO:1903615]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tumor necrosis factor production [GO:0032760]; positive thymic T cell selection [GO:0045059]; protein autophosphorylation [GO:0046777]; protein dephosphorylation [GO:0006470]; regulation of cell cycle [GO:0051726]; regulation of gene expression [GO:0010468]; regulation of interleukin-8 production [GO:0032677]; regulation of phagocytosis [GO:0050764]; regulation of protein tyrosine kinase activity [GO:0061097]; regulation of receptor signaling pathway via JAK-STAT [GO:0046425]; release of sequestered calcium ion into cytosol [GO:0051209]; response to gamma radiation [GO:0010332]; stem cell development [GO:0048864]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852] GO:0000165; GO:0001779; GO:0001915; GO:0001916; GO:0001960; GO:0002244; GO:0002639; GO:0002925; GO:0004725; GO:0005001; GO:0005102; GO:0005886; GO:0005925; GO:0006469; GO:0006470; GO:0006933; GO:0007159; GO:0007166; GO:0008201; GO:0009897; GO:0009898; GO:0009986; GO:0010332; GO:0010468; GO:0016020; GO:0016311; GO:0018108; GO:0019901; GO:0030183; GO:0030217; GO:0030506; GO:0030507; GO:0030667; GO:0030890; GO:0031668; GO:0031953; GO:0032059; GO:0032677; GO:0032703; GO:0032743; GO:0032760; GO:0034113; GO:0035584; GO:0042100; GO:0042102; GO:0042110; GO:0042492; GO:0043395; GO:0043406; GO:0043410; GO:0044770; GO:0044855; GO:0045059; GO:0045060; GO:0045121; GO:0045588; GO:0045860; GO:0046425; GO:0046633; GO:0046641; GO:0046777; GO:0048304; GO:0048539; GO:0048864; GO:0050731; GO:0050764; GO:0050852; GO:0050853; GO:0050857; GO:0051209; GO:0051607; GO:0051726; GO:0061097; GO:0061099; GO:0070062; GO:0070373; GO:0070374; GO:0097191; GO:0098857; GO:1903615; GO:1903979; GO:1904155; GO:1905451; GO:2000473; GO:2000648; GO:2001238 38476 XM_044329299.1 0 0 20 20 7 P08575 1.22e-22 Receptor-type tyrosine-protein phosphatase C (EC 3.1.3.48) (Leukocyte common antigen) (L-CA) (T200) (CD antigen CD45) Homo sapiens (Human) alpha-beta T cell proliferation [GO:0046633]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; B cell receptor signaling pathway [GO:0050853]; bone marrow development [GO:0048539]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell cycle phase transition [GO:0044770]; cell surface receptor signaling pathway [GO:0007166]; cellular response to extracellular stimulus [GO:0031668]; defense response to virus [GO:0051607]; dephosphorylation [GO:0016311]; DN2 thymocyte differentiation [GO:1904155]; extrinsic apoptotic signaling pathway [GO:0097191]; gamma-delta T cell differentiation [GO:0042492]; hematopoietic progenitor cell differentiation [GO:0002244]; heterotypic cell-cell adhesion [GO:0034113]; leukocyte cell-cell adhesion [GO:0007159]; MAPK cascade [GO:0000165]; natural killer cell differentiation [GO:0001779]; negative regulation of cell adhesion involved in substrate-bound cell migration [GO:0006933]; negative regulation of cytokine-mediated signaling pathway [GO:0001960]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of microglial cell activation [GO:1903979]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein tyrosine kinase activity [GO:0061099]; negative regulation of T cell mediated cytotoxicity [GO:0001915]; negative thymic T cell selection [GO:0045060]; peptidyl-tyrosine phosphorylation [GO:0018108]; plasma membrane raft distribution [GO:0044855]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of antigen receptor-mediated signaling pathway [GO:0050857]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis [GO:1905451]; positive regulation of gamma-delta T cell differentiation [GO:0045588]; positive regulation of hematopoietic stem cell migration [GO:2000473]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein tyrosine phosphatase activity [GO:1903615]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tumor necrosis factor production [GO:0032760]; positive thymic T cell selection [GO:0045059]; protein autophosphorylation [GO:0046777]; protein dephosphorylation [GO:0006470]; regulation of cell cycle [GO:0051726]; regulation of gene expression [GO:0010468]; regulation of interleukin-8 production [GO:0032677]; regulation of phagocytosis [GO:0050764]; regulation of protein tyrosine kinase activity [GO:0061097]; regulation of receptor signaling pathway via JAK-STAT [GO:0046425]; release of sequestered calcium ion into cytosol [GO:0051209]; response to gamma radiation [GO:0010332]; stem cell development [GO:0048864]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852] GO:0000165; GO:0001779; GO:0001915; GO:0001916; GO:0001960; GO:0002244; GO:0002639; GO:0002925; GO:0004725; GO:0005001; GO:0005102; GO:0005886; GO:0005925; GO:0006469; GO:0006470; GO:0006933; GO:0007159; GO:0007166; GO:0008201; GO:0009897; GO:0009898; GO:0009986; GO:0010332; GO:0010468; GO:0016020; GO:0016311; GO:0018108; GO:0019901; GO:0030183; GO:0030217; GO:0030506; GO:0030507; GO:0030667; GO:0030890; GO:0031668; GO:0031953; GO:0032059; GO:0032677; GO:0032703; GO:0032743; GO:0032760; GO:0034113; GO:0035584; GO:0042100; GO:0042102; GO:0042110; GO:0042492; GO:0043395; GO:0043406; GO:0043410; GO:0044770; GO:0044855; GO:0045059; GO:0045060; GO:0045121; GO:0045588; GO:0045860; GO:0046425; GO:0046633; GO:0046641; GO:0046777; GO:0048304; GO:0048539; GO:0048864; GO:0050731; GO:0050764; GO:0050852; GO:0050853; GO:0050857; GO:0051209; GO:0051607; GO:0051726; GO:0061097; GO:0061099; GO:0070062; GO:0070373; GO:0070374; GO:0097191; GO:0098857; GO:1903615; GO:1903979; GO:1904155; GO:1905451; GO:2000473; GO:2000648; GO:2001238 38477 XM_044321297.1 293 145 70 120 199 NA NA NA NA NA NA 38478 XM_044319507.1 5 0 5 45 51 NA NA NA NA NA NA 38479 XM_044316667.1 354 129 166 130 339 Q923J1 5.02e-159 Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Channel-kinase 1) (Long transient receptor potential channel 7) (LTrpC-7) (LTrpC7) (Transient receptor potential-phospholipase C-interacting kinase) (TRP-PLIK) Mus musculus (Mouse) actomyosin structure organization [GO:0031032]; calcium ion transport [GO:0006816]; calcium-dependent cell-matrix adhesion [GO:0016340]; cation transmembrane transport [GO:0098655]; cellular magnesium ion homeostasis [GO:0010961]; divalent inorganic cation homeostasis [GO:0072507]; memory [GO:0007613]; necroptotic process [GO:0070266]; positive regulation of apoptotic process [GO:0043065]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein tetramerization [GO:0051262] GO:0001726; GO:0003779; GO:0004672; GO:0004674; GO:0005261; GO:0005262; GO:0005524; GO:0005737; GO:0005886; GO:0006468; GO:0006816; GO:0007613; GO:0010961; GO:0016020; GO:0016301; GO:0016340; GO:0017022; GO:0030672; GO:0031032; GO:0043005; GO:0043025; GO:0043065; GO:0043196; GO:0046777; GO:0046872; GO:0051262; GO:0070266; GO:0072507; GO:0098655; GO:0106310 38480 XR_006391436.1 16 35 69 83 132 NA NA NA NA NA NA 38481 XM_044316084.1 11 0 0 10 7 F1M3J4 6.76e-55 ATP-binding cassette subfamily C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Rattus norvegicus (Rat) bile acid and bile salt transport [GO:0015721]; bile acid signaling pathway [GO:0038183]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to organonitrogen compound [GO:0010243]; response to xenobiotic stimulus [GO:0009410]; transmembrane transport [GO:0055085]; urate transport [GO:0015747] GO:0001409; GO:0005524; GO:0005886; GO:0008559; GO:0009410; GO:0010033; GO:0010243; GO:0014070; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0038183; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115 38482 XM_029344613.2 17 42 19 0 131 NA NA NA NA NA NA 38483 XM_029332385.2 49 0 47 0 78 P78357 1.13e-59 Contactin-associated protein 1 (Caspr) (Caspr1) (Neurexin IV) (Neurexin-4) (p190) Homo sapiens (Human) axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cytoskeleton organization [GO:0007010]; mitochondrion organization [GO:0007005]; myelination in peripheral nervous system [GO:0022011]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; neuron projection morphogenesis [GO:0048812]; neuronal action potential propagation [GO:0019227]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; postsynaptic density organization [GO:0097106]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; regulation of synapse maturation [GO:0090128]; signal transduction [GO:0007165] GO:0002175; GO:0005886; GO:0007005; GO:0007010; GO:0007155; GO:0007165; GO:0007409; GO:0016020; GO:0017124; GO:0019227; GO:0022010; GO:0022011; GO:0030913; GO:0033010; GO:0033270; GO:0038023; GO:0048786; GO:0048812; GO:0050884; GO:0050885; GO:0071205; GO:0090128; GO:0097106; GO:0098529; GO:0098978; GO:1990227 38484 XM_044309835.1 948 169 205 1199 175 Q29RU2 1.64e-35 Oncoprotein-induced transcript 3 protein Bos taurus (Bovine) NA GO:0005509; GO:0005635 38485 XM_044317394.1 11894 7338 11264 12278 14084 O97758 3.51e-82 Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1) Canis lupus familiaris (Dog) (Canis familiaris) bicellular tight junction assembly [GO:0070830]; cell-cell adhesion [GO:0098609]; cell-cell junction organization [GO:0045216]; cellular response to calcium ion [GO:0071277]; establishment of endothelial intestinal barrier [GO:0090557]; positive regulation of blood-brain barrier permeability [GO:1905605]; protein localization to cell-cell junction [GO:0150105] GO:0005516; GO:0005886; GO:0005911; GO:0005921; GO:0005923; GO:0009986; GO:0031410; GO:0045216; GO:0050839; GO:0070160; GO:0070830; GO:0071277; GO:0090557; GO:0098609; GO:0150105; GO:1905605 38486 XM_044317394.1 11894 7338 11264 12278 14084 O97758 9.58e-56 Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1) Canis lupus familiaris (Dog) (Canis familiaris) bicellular tight junction assembly [GO:0070830]; cell-cell adhesion [GO:0098609]; cell-cell junction organization [GO:0045216]; cellular response to calcium ion [GO:0071277]; establishment of endothelial intestinal barrier [GO:0090557]; positive regulation of blood-brain barrier permeability [GO:1905605]; protein localization to cell-cell junction [GO:0150105] GO:0005516; GO:0005886; GO:0005911; GO:0005921; GO:0005923; GO:0009986; GO:0031410; GO:0045216; GO:0050839; GO:0070160; GO:0070830; GO:0071277; GO:0090557; GO:0098609; GO:0150105; GO:1905605 38487 XM_044326308.1 639 283 115 193 438 Q9DC53 0 Copine-8 (Copine VIII) Mus musculus (Mouse) cellular response to calcium ion [GO:0071277] GO:0005544; GO:0005886; GO:0046872; GO:0071277 38488 XM_029352541.2 354 285 383 306 440 NA NA NA NA NA NA 38489 XR_006391861.1 130 242 177 159 238 NA NA NA NA NA NA 38490 XR_006397478.1 694 268 181 527 450 NA NA NA NA NA NA 38491 XM_044319547.1 137 24 355 114 455 NA NA NA NA NA NA 38492 XM_044306786.1 0 0 0 0 12 NA NA NA NA NA NA 38493 XM_029337695.2 73 96 45 30 77 Q32PP1 3.28e-25 MRN complex-interacting protein (MRN-interacting protein) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of protein kinase activity [GO:0045860]; protein localization to chromatin [GO:0071168]; regulation of double-strand break repair via nonhomologous end joining [GO:2001032]; response to ionizing radiation [GO:0010212] GO:0003682; GO:0005634; GO:0005654; GO:0006281; GO:0006974; GO:0007095; GO:0010212; GO:0045860; GO:0071168; GO:1905168; GO:2001032 38494 XM_029345309.2 35 25 5 5 0 Q92113 3.08e-141 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Squalus acanthias (Spiny dogfish) steroid biosynthetic process [GO:0006694] GO:0004508; GO:0005506; GO:0006694; GO:0016020; GO:0020037; GO:0047442 38495 XM_044326926.1 11 53 78 93 53 Q8IYQ7 0 Threonine synthase-like 1 (TSH1) Homo sapiens (Human) NA GO:0005737 38496 XM_029341755.2 62 89 28 68 15 Q6GPE5 1.86e-101 Protein fem-1 homolog B (FEM1b) (FEM1-beta) Xenopus laevis (African clawed frog) apoptotic process [GO:0006915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of DNA damage checkpoint [GO:2000001]; ubiquitin-dependent protein catabolic process via the C-end degron rule pathway [GO:0140627] GO:0005634; GO:0005737; GO:0006915; GO:0016567; GO:0031462; GO:0043161; GO:0140627; GO:1990756; GO:2000001 38497 XM_044309545.1 2 0 0 2 9 NA NA NA NA NA NA 38498 XM_029342465.2 145 47 109 79 73 NA NA NA NA NA NA 38499 XM_044308662.1 244 44 125 56 97 Q96AY4 1.63e-61 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38500 XM_044308662.1 244 44 125 56 97 Q96AY4 2.68e-56 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38501 XM_044308662.1 244 44 125 56 97 Q96AY4 1.15e-53 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38502 XM_044308662.1 244 44 125 56 97 Q96AY4 1.92e-53 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38503 XM_044308662.1 244 44 125 56 97 Q96AY4 1.28e-49 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38504 XM_044308662.1 244 44 125 56 97 Q96AY4 9.51e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38505 XM_044308662.1 244 44 125 56 97 Q96AY4 5.81e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38506 XR_006398071.1 17 26 192 157 31 NA NA NA NA NA NA 38507 XM_044317430.1 24 13 14 15 13 NA NA NA NA NA NA 38508 XM_029330144.2 794 666 371 566 642 Q5BIR5 4.87e-63 Serpin B8 Bos taurus (Bovine) epithelial cell-cell adhesion [GO:0090136]; negative regulation of endopeptidase activity [GO:0010951] GO:0004867; GO:0005615; GO:0005737; GO:0005829; GO:0010951; GO:0090136 38509 XM_029343988.2 71 190 55 188 174 Q9D1D1 6.55e-40 Tetraspanin-11 (Tspan-11) Mus musculus (Mouse) cell migration [GO:0016477] GO:0005886; GO:0016477 38510 XM_044317117.1 192 92 117 76 142 Q0VBU9 3.36e-67 Phospholipid phosphatase 4 (EC 3.1.3.4) (EC 3.6.1.75) Mus musculus (Mouse) blastocyst hatching [GO:0001835]; phospholipid dephosphorylation [GO:0046839]; phospholipid metabolic process [GO:0006644]; regulation of calcium ion import [GO:0090279] GO:0000810; GO:0001835; GO:0006644; GO:0008195; GO:0016020; GO:0042802; GO:0046839; GO:0090279 38511 XM_044321296.1 284 228 236 414 600 Q7RTR2 5.3e-68 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 38512 XM_044321296.1 284 228 236 414 600 Q7RTR2 2.3e-67 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 38513 XM_044321296.1 284 228 236 414 600 Q7RTR2 1.06e-65 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 38514 XM_044321296.1 284 228 236 414 600 Q7RTR2 9.34e-28 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 38515 XM_044307810.1 253 181 252 164 513 Q7RTR2 1.03e-68 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 38516 XM_044307810.1 253 181 252 164 513 Q7RTR2 1.54e-62 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 38517 XM_044307810.1 253 181 252 164 513 Q7RTR2 9.27e-62 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 38518 XM_044307810.1 253 181 252 164 513 Q7RTR2 4.24e-58 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 38519 XM_044307810.1 253 181 252 164 513 Q7RTR2 1.56e-52 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 38520 XM_044320760.1 0 16 0 38 41 NA NA NA NA NA NA 38521 XM_044323584.1 55 0 16 0 0 NA NA NA NA NA NA 38522 XM_029332023.2 66 3 30 32 84 NA NA NA NA NA NA 38523 XM_029343003.2 1500 1518 1190 1684 1449 F1MAB7 0 Diacylglycerol kinase iota (DAG kinase iota) (EC 2.7.1.107) Rattus norvegicus (Rat) diacylglycerol metabolic process [GO:0046339]; excitatory postsynaptic potential [GO:0060079]; habituation [GO:0046959]; intracellular signal transduction [GO:0035556]; lipid phosphorylation [GO:0046834]; neurotransmitter secretion [GO:0007269]; phosphatidic acid biosynthetic process [GO:0006654]; positive regulation of Ras protein signal transduction [GO:0046579]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; Ras protein signal transduction [GO:0007265]; regulation of GTPase activity [GO:0043087]; regulation of long-term synaptic depression [GO:1900452]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of synaptic vesicle exocytosis [GO:2000300] GO:0004143; GO:0005095; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006654; GO:0007205; GO:0007265; GO:0007269; GO:0008021; GO:0014069; GO:0030672; GO:0031267; GO:0032045; GO:0032991; GO:0035556; GO:0043025; GO:0043087; GO:0043197; GO:0043679; GO:0045202; GO:0046339; GO:0046579; GO:0046834; GO:0046872; GO:0046959; GO:0048471; GO:0048786; GO:0051966; GO:0060076; GO:0060079; GO:0097060; GO:0098685; GO:0098793; GO:0098891; GO:0098978; GO:0099147; GO:0099171; GO:1900452; GO:2000300 38524 XM_044312146.1 25 0 18 2 7 NA NA NA NA NA NA 38525 XM_044328217.1 57 0 0 1 0 NA NA NA NA NA NA 38526 XM_044318473.1 1217 839 1175 2383 791 A9ZSY3 1.16e-92 Facilitated trehalose transporter Tret1 (BmTRET1) Bombyx mori (Silk moth) trehalose transport [GO:0015771] GO:0005886; GO:0015574; GO:0015771; GO:0051119 38527 XM_029357711.2 868 527 182 860 497 P70097 3.99e-38 Succinate dehydrogenase cytochrome b560 subunit, mitochondrial (Integral membrane protein CII-3) (QPs-1) (QPs1) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) proton motive force-driven mitochondrial ATP synthesis [GO:0042776]; tricarboxylic acid cycle [GO:0006099] GO:0000104; GO:0005743; GO:0005749; GO:0006099; GO:0009055; GO:0020037; GO:0042776; GO:0046872 38528 XM_044311176.1 0 0 0 12 0 NA NA NA NA NA NA 38529 XM_044317209.1 16 41 45 15 63 NA NA NA NA NA NA 38530 XM_044317123.1 18 0 1988 0 0 NA NA NA NA NA NA 38531 XR_006395298.1 82 68 49 99 64 NA NA NA NA NA NA 38532 XM_029328798.2 0 50 0 120 0 Q14184 3.34e-95 Double C2-like domain-containing protein beta (Doc2-beta) Homo sapiens (Human) calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-dependent activation of synaptic vesicle fusion [GO:0099502]; exocytosis [GO:0006887]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of insulin secretion [GO:0032024]; positive regulation of vesicle fusion [GO:0031340]; protein localization [GO:0008104]; regulation of calcium ion-dependent exocytosis [GO:0017158]; spontaneous neurotransmitter secretion [GO:0061669] GO:0005509; GO:0005544; GO:0005737; GO:0005886; GO:0006887; GO:0008104; GO:0017158; GO:0019905; GO:0031340; GO:0032024; GO:0045202; GO:0045956; GO:0048791; GO:0061669; GO:0098793; GO:0099502 38533 XM_044326881.1 331 194 206 328 335 Q7T0Q5 0 Nucleolar protein 10 Xenopus laevis (African clawed frog) NA GO:0005730 38534 XM_044309198.1 32 10 18 62 140 NA NA NA NA NA NA 38535 XM_044319934.1 7 0 0 0 0 NA NA NA NA NA NA 38536 XM_029337004.2 1706 2474 1751 4660 1064 Q9VVY3 4.69e-24 Glycogen-binding subunit 76A (CBM21 domain-containing protein CG9619) Drosophila melanogaster (Fruit fly) regulation of glycogen biosynthetic process [GO:0005979] GO:0000164; GO:0005979; GO:0008157; GO:2001069 38537 XM_029330852.2 5914 4767 3347 8182 3466 NA NA NA NA NA NA 38538 XM_044312518.1 1683 1124 1075 1294 1466 Q2VUH7 2.35e-64 Dixin (Coiled-coil protein DIX1) (Coiled-coil-DIX1) (DIX domain-containing protein 1) Rattus norvegicus (Rat) canonical Wnt signaling pathway [GO:0060070]; cell proliferation in forebrain [GO:0021846]; cerebellar cortex development [GO:0021695]; cerebral cortex cell migration [GO:0021795]; cerebral cortex radially oriented cell migration [GO:0021799]; forebrain ventricular zone progenitor cell division [GO:0021869]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of axonogenesis [GO:0050772]; positive regulation of JNK cascade [GO:0046330]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of microtubule cytoskeleton organization [GO:0070507] GO:0003779; GO:0005737; GO:0005829; GO:0005856; GO:0005925; GO:0019904; GO:0021695; GO:0021795; GO:0021799; GO:0021846; GO:0021869; GO:0030177; GO:0031435; GO:0032956; GO:0032991; GO:0043015; GO:0043025; GO:0043679; GO:0045665; GO:0046330; GO:0050772; GO:0060070; GO:0070507; GO:0140677 38539 XM_029349489.2 26 0 0 0 0 Q4U4D2 5.36e-48 Melanopsin (Opsin-4) Podarcis siculus (Italian wall lizard) phototransduction [GO:0007602]; visual perception [GO:0007601] GO:0004930; GO:0005886; GO:0007601; GO:0007602; GO:0009881 38540 XM_029348500.2 1224 1144 1101 1282 1289 Q9Y6R4 0 Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAP three kinase 1) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4) Homo sapiens (Human) chorionic trophoblast cell differentiation [GO:0060718]; intracellular signal transduction [GO:0035556]; male germ-line sex determination [GO:0019100]; MAPK cascade [GO:0000165]; placenta development [GO:0001890]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein phosphorylation [GO:0006468]; regulation of gene expression [GO:0010468]; response to UV-C [GO:0010225] GO:0000165; GO:0001890; GO:0004709; GO:0005524; GO:0005737; GO:0006468; GO:0010225; GO:0010468; GO:0019100; GO:0032212; GO:0035556; GO:0043507; GO:0046872; GO:0048471; GO:0051973; GO:0060718; GO:0106310; GO:1900745; GO:1904355 38541 XM_044309081.1 29 36 62 40 73 P70168 2.06e-113 Importin subunit beta-1 (Karyopherin subunit beta-1) (Nuclear factor p97) (Pore targeting complex 97 kDa subunit) (PTAC97) (SCG) Mus musculus (Mouse) astral microtubule organization [GO:0030953]; establishment of mitotic spindle localization [GO:0040001]; establishment of protein localization [GO:0045184]; mitotic chromosome movement towards spindle pole [GO:0007079]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly [GO:0090307]; protein import into nucleus [GO:0006606]; Ran protein signal transduction [GO:0031291]; ribosomal protein import into nucleus [GO:0006610]; RNA import into nucleus [GO:0006404] GO:0005634; GO:0005635; GO:0005643; GO:0005654; GO:0005737; GO:0005829; GO:0006404; GO:0006606; GO:0006610; GO:0007079; GO:0007080; GO:0008139; GO:0010494; GO:0019894; GO:0019899; GO:0019904; GO:0030953; GO:0031267; GO:0031291; GO:0031965; GO:0032991; GO:0040001; GO:0042564; GO:0044877; GO:0045184; GO:0051879; GO:0061608; GO:0061676; GO:0071782; GO:0090307 38542 XM_029349473.2 83 71 17 96 71 NA NA NA NA NA NA 38543 XM_044320273.1 116 11 14 161 177 NA NA NA NA NA NA 38544 XM_029346104.2 523 532 381 584 216 NA NA NA NA NA NA 38545 XM_029328080.2 0 6 0 0 22 Q19546 3.35e-41 ATP-dependent helicase wrn-1 (EC 3.6.4.12) (Werner syndrome protein homolog) Caenorhabditis elegans determination of adult lifespan [GO:0008340]; DNA duplex unwinding [GO:0032508]; DNA metabolic process [GO:0006259]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724]; G-quadruplex DNA unwinding [GO:0044806]; multicellular organism aging [GO:0010259]; response to ionizing radiation [GO:0010212]; telomere maintenance [GO:0000723] GO:0000723; GO:0000724; GO:0003677; GO:0005524; GO:0005634; GO:0005654; GO:0005694; GO:0005737; GO:0006259; GO:0006268; GO:0006281; GO:0006310; GO:0008340; GO:0009378; GO:0010212; GO:0010259; GO:0016887; GO:0032508; GO:0035861; GO:0043138; GO:0044806 38546 XM_029330812.2 2 3 8 18 17 Q68DL7 3.68e-61 Uncharacterized protein C18orf63 Homo sapiens (Human) NA NA 38547 XR_006392889.1 41 2 25 5 151 NA NA NA NA NA NA 38548 XM_044329340.1 179 52 0 21 83 Q21279 5.11e-102 Probable tubulin polyglutamylase ttll-15 (EC 6.-.-.-) (Tubulin--tyrosine ligase-like protein 15) Caenorhabditis elegans oviposition [GO:0018991]; protein modification process [GO:0036211] GO:0005524; GO:0016874; GO:0018991; GO:0036211 38549 XM_044324110.1 0 0 0 14 1 NA NA NA NA NA NA 38550 XM_044307802.1 138 77 37 75 105 Q7RTR2 1.63e-32 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 38551 XM_044307802.1 138 77 37 75 105 Q7RTR2 1.65e-31 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 38552 XM_044307802.1 138 77 37 75 105 Q7RTR2 1.88e-30 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 38553 XM_044307802.1 138 77 37 75 105 Q7RTR2 1.6e-29 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 38554 XM_029351862.2 208 91 73 299 478 Q8CC12 1.37e-115 Codanin-1 Mus musculus (Mouse) chromatin organization [GO:0006325]; import into nucleus [GO:0051170]; nuclear envelope organization [GO:0006998]; protein localization [GO:0008104] GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0006325; GO:0006998; GO:0008104; GO:0012505; GO:0051170 38555 XM_029345378.2 4595 4743 3371 5221 2570 Q6PCJ9 2.24e-92 Lysosomal thioesterase PPT2-A (PPT-2-A) (EC 3.1.2.-) Xenopus laevis (African clawed frog) NA GO:0005764; GO:0016787 38556 XR_006392311.1 90 33 24 24 161 NA NA NA NA NA NA 38557 XM_044309914.1 118 2 5 9 33 NA NA NA NA NA NA 38558 XM_044316007.1 84 16 24 40 82 NA NA NA NA NA NA 38559 XM_029345527.2 33 13 11 12 21 Q09575 4.13e-33 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 38560 XM_029333285.2 0 0 17 16 0 P83858 4.72e-27 Pyroglutamylated RF-amide peptide receptor (AQ27) (G-protein coupled receptor 103) (Orexigenic neuropeptide QRFP receptor) (SP9155) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:0097730 38561 XM_044326165.1 2 5 5 5 12 NA NA NA NA NA NA 38562 XM_044310189.1 51 0 21 5 91 NA NA NA NA NA NA 38563 XM_044318248.1 45 0 11 11 81 NA NA NA NA NA NA 38564 XM_029347010.2 187 88 65 213 168 P24044 8.49e-44 Calmodulin Plasmodium falciparum NA GO:0005509; GO:0005737; GO:0020007 38565 XM_029354983.2 1 4 15 11 22 NA NA NA NA NA NA 38566 XR_006396082.1 8 3 15 0 55 NA NA NA NA NA NA 38567 XM_044319672.1 29 0 55 0 152 Q69Z28 2.55e-159 A disintegrin and metalloproteinase with thrombospondin motifs 16 (ADAM-TS 16) (ADAM-TS16) (ADAMTS-16) (EC 3.4.24.-) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; extracellular matrix organization [GO:0030198]; male gamete generation [GO:0048232]; proteolysis [GO:0006508]; regulation of cilium assembly [GO:1902017]; regulation of systemic arterial blood pressure [GO:0003073] GO:0001658; GO:0003073; GO:0004222; GO:0005576; GO:0006508; GO:0030198; GO:0031012; GO:0046872; GO:0048232; GO:1902017 38568 XM_044313629.1 99 141 61 127 312 Q8N531 1.5e-36 F-box/LRR-repeat protein 6 (F-box and leucine-rich repeat protein 6) (F-box protein FBL6) (FBL6A) Homo sapiens (Human) entrainment of circadian clock by photoperiod [GO:0043153]; G2/M transition of mitotic cell cycle [GO:0000086]; proteolysis [GO:0006508]; regulation of cell cycle [GO:0051726]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0000086; GO:0004842; GO:0005634; GO:0005829; GO:0006508; GO:0019005; GO:0031146; GO:0043153; GO:0051726 38569 XM_029334723.2 1214 1822 415 1563 1092 P62997 1.72e-43 Transformer-2 protein homolog beta (TRA-2 beta) (TRA2-beta) (RA301) (Splicing factor, arginine/serine-rich 10) (Transformer-2 protein homolog B) Rattus norvegicus (Rat) cellular response to glucose stimulus [GO:0071333]; cerebral cortex regionalization [GO:0021796]; embryonic brain development [GO:1990403]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of RNA splicing [GO:0043484]; response to reactive oxygen species [GO:0000302] GO:0000302; GO:0000381; GO:0000398; GO:0001673; GO:0003723; GO:0003729; GO:0005634; GO:0005637; GO:0005681; GO:0019904; GO:0021796; GO:0032991; GO:0036002; GO:0042802; GO:0043484; GO:0048026; GO:0048471; GO:0071333; GO:1990403 38570 XM_029346540.2 207 17 64 60 97 P49582 1.46e-85 Neuronal acetylcholine receptor subunit alpha-7 Mus musculus (Mouse) acetylcholine receptor signaling pathway [GO:0095500]; associative learning [GO:0008306]; B cell activation [GO:0042113]; behavioral response to ethanol [GO:0048149]; behavioral response to nicotine [GO:0035095]; calcium ion transport [GO:0006816]; chemical synaptic transmission [GO:0007268]; dendrite arborization [GO:0140059]; dendritic spine organization [GO:0097061]; endocytosis [GO:0006897]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; generation of ovulation cycle rhythm [GO:0060112]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; learning or memory [GO:0007611]; membrane depolarization [GO:0051899]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; modulation of excitatory postsynaptic potential [GO:0098815]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of tumor necrosis factor production [GO:0032720]; nervous system process [GO:0050877]; neuronal action potential [GO:0019228]; ovulation cycle [GO:0042698]; positive regulation of acetylcholine biosynthetic process [GO:1905923]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of CoA-transferase activity [GO:1905920]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure [GO:0001988]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of amyloid fibril formation [GO:1905906]; regulation of inflammatory response [GO:0050727]; regulation of membrane potential [GO:0042391]; regulation of neuron death [GO:1901214]; regulation of nitric oxide metabolic process [GO:0080164]; regulation of norepinephrine secretion [GO:0014061]; regulation of response to drug [GO:2001023]; regulation of synapse structural plasticity [GO:0051823]; regulation of synaptic transmission, cholinergic [GO:0032222]; regulation of synaptic transmission, dopaminergic [GO:0032225]; response to acetylcholine [GO:1905144]; response to amyloid-beta [GO:1904645]; response to cold [GO:0009409]; response to ethanol [GO:0045471]; response to food [GO:0032094]; response to nicotine [GO:0035094]; sensory processing [GO:0050893]; signal transduction [GO:0007165]; synapse organization [GO:0050808]; synaptic transmission, cholinergic [GO:0007271]; T cell activation [GO:0042110] GO:0001540; GO:0001933; GO:0001934; GO:0001988; GO:0005216; GO:0005231; GO:0005737; GO:0005886; GO:0005892; GO:0006811; GO:0006816; GO:0006897; GO:0007165; GO:0007268; GO:0007271; GO:0007611; GO:0007613; GO:0008179; GO:0008306; GO:0009409; GO:0009897; GO:0010628; GO:0014061; GO:0014069; GO:0015464; GO:0015643; GO:0016020; GO:0016324; GO:0017081; GO:0019228; GO:0019901; GO:0022848; GO:0030317; GO:0030424; GO:0030425; GO:0030426; GO:0030594; GO:0030673; GO:0032094; GO:0032222; GO:0032225; GO:0032279; GO:0032691; GO:0032715; GO:0032720; GO:0033138; GO:0034220; GO:0035094; GO:0035095; GO:0042110; GO:0042113; GO:0042166; GO:0042391; GO:0042698; GO:0042734; GO:0042803; GO:0043005; GO:0043025; GO:0043197; GO:0043198; GO:0044853; GO:0045121; GO:0045202; GO:0045211; GO:0045471; GO:0048149; GO:0050727; GO:0050728; GO:0050804; GO:0050808; GO:0050877; GO:0050893; GO:0051117; GO:0051247; GO:0051649; GO:0051823; GO:0051899; GO:0060112; GO:0070373; GO:0070374; GO:0080164; GO:0095500; GO:0097061; GO:0097110; GO:0098690; GO:0098793; GO:0098815; GO:0098897; GO:0098981; GO:0099171; GO:0099634; GO:0140059; GO:1900273; GO:1901214; GO:1902004; GO:1904315; GO:1904645; GO:1905144; GO:1905906; GO:1905920; GO:1905923; GO:2000463; GO:2001023 38571 XM_029331326.2 0 0 60 59 166 Q9YH18 1.19e-58 KH domain-containing RNA-binding protein QKI (Protein quaking) Gallus gallus (Chicken) long-chain fatty acid biosynthetic process [GO:0042759]; mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; myelination [GO:0042552]; positive regulation of gene expression [GO:0010628]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of translation [GO:0006417]; RNA splicing [GO:0008380]; spermatid development [GO:0007286]; vascular associated smooth muscle cell differentiation [GO:0035886]; vasculogenesis [GO:0001570] GO:0001570; GO:0003729; GO:0005634; GO:0005737; GO:0006397; GO:0006417; GO:0007286; GO:0008380; GO:0010628; GO:0017124; GO:0035886; GO:0042552; GO:0042759; GO:0045202; GO:0048024; GO:0051028 38572 XM_044329352.1 11 16 35 41 43 P97363 1.24e-177 Serine palmitoyltransferase 2 (EC 2.3.1.50) (Long chain base biosynthesis protein 2) (LCB 2) (Long chain base biosynthesis protein 2a) (LCB2a) (Serine-palmitoyl-CoA transferase 2) (SPT 2) Mus musculus (Mouse) adipose tissue development [GO:0060612]; ceramide biosynthetic process [GO:0046513]; lipophagy [GO:0061724]; positive regulation of lipophagy [GO:1904504]; sphinganine biosynthetic process [GO:0046511]; sphingolipid biosynthetic process [GO:0030148]; sphingomyelin biosynthetic process [GO:0006686]; sphingosine biosynthetic process [GO:0046512] GO:0004758; GO:0005739; GO:0005789; GO:0006686; GO:0017059; GO:0030148; GO:0030170; GO:0046511; GO:0046512; GO:0046513; GO:0060612; GO:0061724; GO:1904504 38573 XM_029333942.2 320 193 118 152 226 Q14739 2.58e-124 Delta(14)-sterol reductase LBR (Delta-14-SR) (EC 1.3.1.70) (3-beta-hydroxysterol Delta (14)-reductase) (C-14 sterol reductase) (C14SR) (Integral nuclear envelope inner membrane protein) (LMN2R) (Lamin-B receptor) (Sterol C14-reductase) Homo sapiens (Human) cholesterol biosynthetic process [GO:0006695]; neutrophil differentiation [GO:0030223]; sterol biosynthetic process [GO:0016126] GO:0003677; GO:0003723; GO:0005521; GO:0005634; GO:0005635; GO:0005637; GO:0005737; GO:0005789; GO:0006695; GO:0016020; GO:0016126; GO:0016627; GO:0030223; GO:0031965; GO:0050613; GO:0070087; GO:0070402 38574 XM_044328342.1 52 352 32 112 175 Q58DM8 5.97e-128 Enoyl-CoA hydratase, mitochondrial (mECH) (mECH1) (EC 4.2.1.17) (EC 5.3.3.8) (Enoyl-CoA hydratase 1) (ECHS1) (Short-chain enoyl-CoA hydratase) (SCEH) Bos taurus (Bovine) fatty acid beta-oxidation [GO:0006635] GO:0004165; GO:0004300; GO:0005739; GO:0005759; GO:0006635; GO:0043956; GO:0120092 38575 XR_006394251.1 46 0 10 72 115 NA NA NA NA NA NA 38576 XR_006393932.1 0 0 26 3 13 NA NA NA NA NA NA 38577 XR_003827434.2 216 677 722 75 129 NA NA NA NA NA NA 38578 XM_029346445.2 97 89 108 136 185 NA NA NA NA NA NA 38579 XM_029345845.2 2619 2360 1635 1731 1718 P22439 3.14e-127 Pyruvate dehydrogenase protein X component (Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex) (E3-binding protein) (E3BP) (proX) Bos taurus (Bovine) NA GO:0005739; GO:0005967; GO:0016746; GO:0034604; GO:0045254 38580 XM_029333658.2 1208 925 241 808 807 Q6P5L8 1.74e-154 Hydroxysteroid dehydrogenase-like protein 2 (EC 1.-.-.-) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005739; GO:0005777; GO:0016491 38581 XM_044315139.1 4 62 9 56 0 NA NA NA NA NA NA 38582 XM_029358050.2 1093 811 281 674 1375 Q5R4G6 0 Cullin-1 (CUL-1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; cell population proliferation [GO:0008283]; protein K48-linked ubiquitination [GO:0070936]; protein monoubiquitination [GO:0006513]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0005886; GO:0006513; GO:0006915; GO:0008283; GO:0009887; GO:0019005; GO:0031146; GO:0031625; GO:0070936; GO:1990452 38583 XM_029357415.2 1014 678 426 827 783 A2RRS8 1.05e-111 Centrosomal protein of 78 kDa (Cep78) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cilium organization [GO:0044782] GO:0005737; GO:0005814; GO:0036064; GO:0044782 38584 XM_044323662.1 26 0 0 0 0 NA NA NA NA NA NA 38585 XR_006397338.1 4 6 0 0 7 NA NA NA NA NA NA 38586 XM_044315229.1 25 11 10 20 10 NA NA NA NA NA NA 38587 XR_006391666.1 5 5 0 5 25 NA NA NA NA NA NA 38588 XM_044329048.1 102 30 80 116 177 Q6L8S8 1.67e-58 Beta-1,4-N-acetylgalactosaminyltransferase 3 (Beta4GalNAc-T3) (Beta4GalNAcT3) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase III) (N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 2) (NGalNAc-T2) Mus musculus (Mouse) chondroitin sulfate biosynthetic process [GO:0030206] GO:0005794; GO:0008376; GO:0030206; GO:0032580; GO:0033842; GO:0043231; GO:0047238 38589 XM_044312155.1 94 15 0 5 3 NA NA NA NA NA NA 38590 XM_029340161.2 255 211 165 384 463 Q969N2 3.36e-167 GPI transamidase component PIG-T (Phosphatidylinositol-glycan biosynthesis class T protein) Homo sapiens (Human) attachment of GPI anchor to protein [GO:0016255]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182] GO:0005789; GO:0016020; GO:0016255; GO:0030182; GO:0031410; GO:0042765; GO:0051402 38591 XM_029346235.2 2053 2088 1094 1853 2409 Q9Y6N5 8.77e-161 Sulfide:quinone oxidoreductase, mitochondrial (SQOR) (EC 1.8.5.8) (Sulfide dehydrogenase-like) (Sulfide quinone oxidoreductase) Homo sapiens (Human) sulfide oxidation, using sulfide:quinone oxidoreductase [GO:0070221] GO:0005739; GO:0005743; GO:0048038; GO:0070221; GO:0070224; GO:0071949; GO:0106436 38592 XM_029324786.2 23 0 25 25 36 NA NA NA NA NA NA 38593 XR_003824942.2 17 167 8 6 50 NA NA NA NA NA NA 38594 XM_044325414.1 1226 1024 899 1354 1600 Q9DBN1 8.48e-35 Stimulated by retinoic acid gene 6 protein-like (STRA6-like protein) (Retinol-binding protein 4 receptor 2) (RBP4 receptor 2) Mus musculus (Mouse) establishment of localization in cell [GO:0051649]; retinol transport [GO:0034633]; vitamin A import into cell [GO:0071939] GO:0005886; GO:0034633; GO:0051649; GO:0071939 38595 XM_044312495.1 300 266 136 722 227 NA NA NA NA NA NA 38596 XR_006395094.1 157 5 149 102 121 NA NA NA NA NA NA 38597 XM_044322512.1 0 170 6 120 66 NA NA NA NA NA NA 38598 XR_003824300.2 0 25 17 19 9 NA NA NA NA NA NA 38599 XM_029334404.2 181 70 24 110 109 Q90Z12 8.52e-24 Transcription factor HES-4-A (Hairy and enhancer of split 4-A) (Protein hairy-2) (Xhairy2) (Protein hairy-2a) (Xhairy2a) Xenopus laevis (African clawed frog) BMP signaling pathway [GO:0030509]; floor plate development [GO:0033504]; lens development in camera-type eye [GO:0002088]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural crest formation [GO:0014029]; prechordal plate formation [GO:0021501] GO:0000122; GO:0002088; GO:0005634; GO:0014029; GO:0021501; GO:0030509; GO:0033504; GO:0043066; GO:0043425; GO:0043565; GO:0045892; GO:0046983 38600 XM_029348406.2 2524 1358 1107 1069 1118 P23709 7.62e-113 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (EC 7.1.1.2) (Complex I-30kD) (CI-30kD) (NADH-ubiquinone oxidoreductase 30 kDa subunit) Bos taurus (Bovine) mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrial respiratory chain complex I assembly [GO:0032981]; negative regulation of cell growth [GO:0030308]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; reactive oxygen species metabolic process [GO:0072593] GO:0003954; GO:0005743; GO:0005747; GO:0006120; GO:0008137; GO:0030308; GO:0031966; GO:0032981; GO:0072593; GO:2001243 38601 XR_003825089.2 98 39 0 29 24 NA NA NA NA NA NA 38602 XM_029336464.2 21 24 13 28 33 P30937 2.84e-22 Somatostatin receptor type 4 (SS-4-R) (SS4-R) (SS4R) Rattus norvegicus (Rat) cell migration [GO:0016477]; cellular response to glucocorticoid stimulus [GO:0071385]; forebrain development [GO:0030900]; negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0106072]; neuropeptide signaling pathway [GO:0007218]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0004930; GO:0004994; GO:0005737; GO:0005886; GO:0007218; GO:0016477; GO:0030900; GO:0042277; GO:0042923; GO:0043005; GO:0070374; GO:0071385; GO:0090238; GO:0106072 38603 XM_029334908.2 2682 2324 871 1064 1040 NA NA NA NA NA NA 38604 XM_029356087.2 1197 425 397 1129 539 NA NA NA NA NA NA 38605 XM_029344131.2 0 3 60 31 4 P02720 2.34e-60 Phosphatidylcholine transfer protein (PC-TP) (START domain-containing protein 2) (StARD2) (StAR-related lipid transfer protein 2) Bos taurus (Bovine) phospholipid transport [GO:0015914] GO:0005737; GO:0008525; GO:0015914; GO:0031210 38606 XM_044317809.1 94 170 124 113 92 Q9UH36 2.6e-41 SRR1-like protein (SRR1 domain-containing protein) Homo sapiens (Human) heme biosynthetic process [GO:0006783]; microtubule-based process [GO:0007017]; regulation of circadian rhythm [GO:0042752]; regulation of heme biosynthetic process [GO:0070453]; rhythmic process [GO:0048511] GO:0005634; GO:0005737; GO:0006783; GO:0007017; GO:0042752; GO:0048511; GO:0070453 38607 XM_044314366.1 7 0 6 1 36 NA NA NA NA NA NA 38608 XM_029356621.2 0 10 7 0 13 NA NA NA NA NA NA 38609 XM_044319100.1 285 225 174 338 103 NA NA NA NA NA NA 38610 XM_029336015.2 12 0 0 0 0 Q7Z2H8 1.98e-21 Proton-coupled amino acid transporter 1 (Proton/amino acid transporter 1) (hPAT1) (Solute carrier family 36 member 1) Homo sapiens (Human) alanine transport [GO:0032328]; amino acid import across plasma membrane [GO:0089718]; amino acid transmembrane transport [GO:0003333]; amino acid transport [GO:0006865]; glycine transport [GO:0015816]; ion transport [GO:0006811]; L-alanine transport [GO:0015808]; proline transmembrane transport [GO:0035524]; proline transport [GO:0015824]; proton transmembrane transport [GO:1902600]; taurine transport [GO:0015734] GO:0003333; GO:0005280; GO:0005297; GO:0005368; GO:0005765; GO:0005783; GO:0005886; GO:0006811; GO:0006865; GO:0015171; GO:0015179; GO:0015180; GO:0015187; GO:0015193; GO:0015734; GO:0015808; GO:0015816; GO:0015824; GO:0016324; GO:0022858; GO:0032328; GO:0035524; GO:0089718; GO:1902600 38611 XM_044315770.1 255 114 135 124 356 P21127 4.48e-97 Cyclin-dependent kinase 11B (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 1) (CLK-1) (Cell division protein kinase 11B) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L1) (p58 CLK-1) Homo sapiens (Human) apoptotic process [GO:0006915]; mitotic cell cycle [GO:0000278]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell growth [GO:0001558]; regulation of centrosome cycle [GO:0046605]; regulation of DNA-templated transcription [GO:0006355]; regulation of mitotic cell cycle [GO:0007346]; regulation of mRNA processing [GO:0050684]; regulation of RNA splicing [GO:0043484] GO:0000278; GO:0000307; GO:0001558; GO:0003723; GO:0004672; GO:0004674; GO:0004693; GO:0005524; GO:0005634; GO:0005737; GO:0006355; GO:0006468; GO:0006915; GO:0007346; GO:0042981; GO:0043484; GO:0046605; GO:0050684; GO:0051726; GO:0106310 38612 XM_044315770.1 255 114 135 124 356 P21127 4.48e-97 Cyclin-dependent kinase 11B (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 1) (CLK-1) (Cell division protein kinase 11B) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L1) (p58 CLK-1) Homo sapiens (Human) apoptotic process [GO:0006915]; mitotic cell cycle [GO:0000278]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell growth [GO:0001558]; regulation of centrosome cycle [GO:0046605]; regulation of DNA-templated transcription [GO:0006355]; regulation of mitotic cell cycle [GO:0007346]; regulation of mRNA processing [GO:0050684]; regulation of RNA splicing [GO:0043484] GO:0000278; GO:0000307; GO:0001558; GO:0003723; GO:0004672; GO:0004674; GO:0004693; GO:0005524; GO:0005634; GO:0005737; GO:0006355; GO:0006468; GO:0006915; GO:0007346; GO:0042981; GO:0043484; GO:0046605; GO:0050684; GO:0051726; GO:0106310 38613 XM_044315770.1 255 114 135 124 356 P21127 4.48e-97 Cyclin-dependent kinase 11B (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 1) (CLK-1) (Cell division protein kinase 11B) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L1) (p58 CLK-1) Homo sapiens (Human) apoptotic process [GO:0006915]; mitotic cell cycle [GO:0000278]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell growth [GO:0001558]; regulation of centrosome cycle [GO:0046605]; regulation of DNA-templated transcription [GO:0006355]; regulation of mitotic cell cycle [GO:0007346]; regulation of mRNA processing [GO:0050684]; regulation of RNA splicing [GO:0043484] GO:0000278; GO:0000307; GO:0001558; GO:0003723; GO:0004672; GO:0004674; GO:0004693; GO:0005524; GO:0005634; GO:0005737; GO:0006355; GO:0006468; GO:0006915; GO:0007346; GO:0042981; GO:0043484; GO:0046605; GO:0050684; GO:0051726; GO:0106310 38614 XM_044307388.1 441 214 538 1205 1200 Q5U374 2.29e-51 Kelch-like protein 12 Danio rerio (Zebrafish) (Brachydanio rerio) anterior/posterior pattern specification [GO:0009952]; convergent extension involved in axis elongation [GO:0060028]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; protein monoubiquitination [GO:0006513]; Wnt signaling pathway [GO:0016055] GO:0006513; GO:0006888; GO:0009952; GO:0014029; GO:0014032; GO:0016055; GO:0030127; GO:0030134; GO:0031463; GO:0048208; GO:0060028 38615 XM_044313964.1 17 50 20 3 38 NA NA NA NA NA NA 38616 XM_044315431.1 21 0 9 17 39 Q7RTR2 3.81e-58 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 38617 XM_044315431.1 21 0 9 17 39 Q7RTR2 5.54e-58 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 38618 XM_044315431.1 21 0 9 17 39 Q7RTR2 8.73e-45 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 38619 XM_044315431.1 21 0 9 17 39 Q7RTR2 1.14e-24 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 38620 XM_044315431.1 21 0 9 17 39 Q7RTR2 1.14e-24 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 38621 XM_044309965.1 206 55 104 186 140 Q6DG99 5.93e-22 BTB/POZ domain-containing protein KCTD6 Danio rerio (Zebrafish) (Brachydanio rerio) protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567] GO:0016567; GO:0051260 38622 XM_029340720.2 48 138 88 54 24 Q3UZD5 5.09e-35 Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.361) (PR domain zinc finger protein 6) (PR domain-containing protein 6) (PR domain-containing protein in smooth muscle) Mus musculus (Mouse) chromatin organization [GO:0006325]; histone methylation [GO:0016571]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of smooth muscle cell differentiation [GO:0051151]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of gene expression [GO:0010468] GO:0000122; GO:0005634; GO:0006325; GO:0010468; GO:0016571; GO:0022008; GO:0042802; GO:0045892; GO:0046872; GO:0051151; GO:0140944 38623 XM_029335289.2 312 369 121 267 417 Q09694 2.46e-91 Saccharopine dehydrogenase [NAD(+), L-lysine-forming] (SDH) (EC 1.5.1.7) (Lysine--2-oxoglutarate reductase) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) lysine biosynthetic process [GO:0009085]; lysine biosynthetic process via aminoadipic acid [GO:0019878] GO:0004753; GO:0004754; GO:0005737; GO:0009085; GO:0019878 38624 XM_044322045.1 792 525 781 855 1110 P27170 1.79e-40 Serum paraoxonase/arylesterase 1 (PON 1) (EC 3.1.1.2) (EC 3.1.1.81) (EC 3.1.8.1) (Aromatic esterase 1) (A-esterase 1) (Serum aryldialkylphosphatase 1) Oryctolagus cuniculus (Rabbit) response to organophosphorus [GO:0046683] GO:0004063; GO:0004064; GO:0005509; GO:0016209; GO:0034364; GO:0046683; GO:0102007 38625 XM_029328923.2 1516 1561 873 592 902 Q7ZW46 4.06e-121 UDP-xylose and UDP-N-acetylglucosamine transporter (Solute carrier family 35 member B4) Danio rerio (Zebrafish) (Brachydanio rerio) carbohydrate transport [GO:0008643] GO:0000139; GO:0005462; GO:0005464; GO:0005789; GO:0008643; GO:0022857 38626 XM_029342873.2 2 9 2 2 0 NA NA NA NA NA NA 38627 XM_044320382.1 201 0 0 1106 459 Q14517 0 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 38628 XM_044320382.1 201 0 0 1106 459 Q14517 6.62e-55 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 38629 XM_044320382.1 201 0 0 1106 459 Q14517 1.09e-34 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 38630 XM_029342020.2 1434 1004 622 1072 1111 Q4R6F8 0 T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0005524; GO:0005832; GO:0016887; GO:0051082; GO:0140662 38631 XM_044318040.1 113 288 368 299 350 Q6DCD1 0 FGGY carbohydrate kinase domain-containing protein (EC 2.7.1.-) Xenopus laevis (African clawed frog) carbohydrate metabolic process [GO:0005975]; phosphorylation [GO:0016310] GO:0005975; GO:0016301; GO:0016310; GO:0016773 38632 XM_029333898.2 31 0 0 0 0 Q9UHJ3 2.44e-57 Scm-like with four MBT domains protein 1 (hSFMBT) (Renal ubiquitous protein 1) Homo sapiens (Human) cell differentiation [GO:0030154]; chromatin organization [GO:0006325]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of muscle organ development [GO:0048635]; spermatogenesis [GO:0007283] GO:0003682; GO:0003714; GO:0005634; GO:0005654; GO:0006325; GO:0007283; GO:0030154; GO:0042393; GO:0045892; GO:0048635 38633 XM_029333898.2 31 0 0 0 0 Q9UHJ3 1.27e-32 Scm-like with four MBT domains protein 1 (hSFMBT) (Renal ubiquitous protein 1) Homo sapiens (Human) cell differentiation [GO:0030154]; chromatin organization [GO:0006325]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of muscle organ development [GO:0048635]; spermatogenesis [GO:0007283] GO:0003682; GO:0003714; GO:0005634; GO:0005654; GO:0006325; GO:0007283; GO:0030154; GO:0042393; GO:0045892; GO:0048635 38634 XM_044328776.1 0 0 6 0 0 NA NA NA NA NA NA 38635 XM_029333155.2 3 0 0 8 25 NA NA NA NA NA NA 38636 XM_044315474.1 25 0 0 0 11 NA NA NA NA NA NA 38637 XM_044312287.1 0 0 85 0 0 Q9U6Y6 4.83e-111 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 38638 XR_006393146.1 1111 2072 1908 1638 1377 NA NA NA NA NA NA 38639 XM_029332337.2 13 0 70 20 87 NA NA NA NA NA NA 38640 XM_029340605.2 261 156 104 127 102 NA NA NA NA NA NA 38641 XM_044326255.1 9 7 7 23 0 C3VPR6 2.78e-26 Protein NLRC5 Mus musculus (Mouse) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of type II interferon-mediated signaling pathway [GO:0060335]; regulation of kinase activity [GO:0043549]; response to bacterium [GO:0009617] GO:0000978; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0009617; GO:0032088; GO:0035556; GO:0043549; GO:0045087; GO:0045345; GO:0045944; GO:0051607; GO:0060335; GO:0060339; GO:0060340 38642 XM_029345134.2 424 360 325 503 750 P59723 2.85e-68 Hypoxia-inducible factor 1-alpha inhibitor (EC 1.14.11.30) (EC 1.14.11.n4) (Hypoxia-inducible factor asparagine hydroxylase) Danio rerio (Zebrafish) (Brachydanio rerio) negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061428]; negative regulation of vasculature development [GO:1901343]; peptidyl-aspartic acid hydroxylation [GO:0042264]; peptidyl-histidine hydroxylation [GO:0036138]; regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030947] GO:0005634; GO:0005737; GO:0008198; GO:0008270; GO:0016706; GO:0030947; GO:0031406; GO:0036138; GO:0036139; GO:0036140; GO:0042264; GO:0042803; GO:0045746; GO:0048471; GO:0061428; GO:0062101; GO:0071532; GO:1901343 38643 XM_029356994.2 1074 1020 537 1134 903 O35125 3.43e-106 Leucine-rich repeat-containing protein 23 (Leucine-rich protein B7) Mus musculus (Mouse) NA GO:0005737; GO:0005829 38644 XM_029347041.2 26424 25615 19356 32444 27354 Q92005 0 Elongation factor 1-alpha (EF-1-alpha) Danio rerio (Zebrafish) (Brachydanio rerio) translation [GO:0006412]; translational elongation [GO:0006414] GO:0003746; GO:0003924; GO:0005525; GO:0005737; GO:0006412; GO:0006414 38645 XM_029330688.2 762 475 378 594 711 O75521 1.95e-131 Enoyl-CoA delta isomerase 2 (EC 5.3.3.8) (DRS-1) (Delta(3),delta(2)-enoyl-CoA isomerase) (D3,D2-enoyl-CoA isomerase) (Diazepam-binding inhibitor-related protein 1) (DBI-related protein 1) (Dodecenoyl-CoA isomerase) (Hepatocellular carcinoma-associated antigen 88) (Peroxisomal 3,2-trans-enoyl-CoA isomerase) (pECI) (Renal carcinoma antigen NY-REN-1) Homo sapiens (Human) fatty acid beta-oxidation [GO:0006635]; fatty acid catabolic process [GO:0009062]; fatty acid metabolic process [GO:0006631] GO:0000062; GO:0004165; GO:0005739; GO:0005777; GO:0005782; GO:0005829; GO:0006631; GO:0006635; GO:0009062; GO:0016020; GO:0043231 38646 XM_044312490.1 0 16 0 11 7 NA NA NA NA NA NA 38647 XR_006391776.1 387 193 190 140 191 NA NA NA NA NA NA 38648 XM_044325657.1 153 63 25 37 22 Q3MIE0 8.07e-121 Enoyl-CoA hydratase domain-containing protein 3, mitochondrial Rattus norvegicus (Rat) fatty acid metabolic process [GO:0006631]; positive regulation of cellular response to insulin stimulus [GO:1900078] GO:0004300; GO:0005739; GO:0006631; GO:0016836; GO:1900078 38649 XM_044313545.1 20 18 68 27 34 NA NA NA NA NA NA 38650 XM_044307190.1 85 8 6 119 80 NA NA NA NA NA NA 38651 XM_029346528.2 141 37 23 97 91 Q9I8C7 9.96e-93 Neuronal acetylcholine receptor subunit alpha-10 (Alpha 10 nAChR) (Nicotinic acetylcholine receptor subunit alpha-10) (NACHR alpha-10) Gallus gallus (Chicken) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; response to auditory stimulus [GO:0010996]; signal transduction [GO:0007165] GO:0004888; GO:0005231; GO:0005262; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0010996; GO:0022848; GO:0030594; GO:0034220; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051899; GO:1904315 38652 XM_044310830.1 38 22 8 17 49 NA NA NA NA NA NA 38653 XR_003826385.2 148 180 114 15 35 NA NA NA NA NA NA 38654 XM_044314881.1 52 59 49 12 168 NA NA NA NA NA NA 38655 XM_029339790.2 343 125 158 277 192 NA NA NA NA NA NA 38656 XM_029349800.2 294 209 189 300 230 M9PBE2 2.2e-36 E3 ubiquitin-protein ligase Hakai (EC 2.3.2.27) Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; chitin-based cuticle development [GO:0040003]; dorsal closure [GO:0007391]; epithelial cell migration, open tracheal system [GO:0007427]; epithelium development [GO:0060429]; female sex determination [GO:0030237]; head involution [GO:0008258]; midgut development [GO:0007494]; mRNA methylation [GO:0080009]; protein ubiquitination [GO:0016567]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of cell adhesion [GO:0030155]; segmentation [GO:0035282] GO:0000381; GO:0004842; GO:0005634; GO:0005829; GO:0005886; GO:0007015; GO:0007391; GO:0007427; GO:0007494; GO:0008258; GO:0008270; GO:0016567; GO:0030155; GO:0030237; GO:0031410; GO:0035282; GO:0036396; GO:0040003; GO:0045296; GO:0048471; GO:0060429; GO:0061630; GO:0080009 38657 XR_003828565.2 53 35 67 27 110 Q5U2R1 4.92e-67 All trans-polyprenyl-diphosphate synthase PDSS2 (All-trans-decaprenyl-diphosphate synthase subunit 2) (EC 2.5.1.91) (Decaprenyl-diphosphate synthase subunit 2) (Solanesyl-diphosphate synthase subunit 2) Rattus norvegicus (Rat) cerebellum development [GO:0021549]; isoprenoid biosynthetic process [GO:0008299]; regulation of body fluid levels [GO:0050878]; ubiquinone biosynthetic process [GO:0006744] GO:0000010; GO:0004659; GO:0005739; GO:0005829; GO:0006744; GO:0008299; GO:0021549; GO:0046982; GO:0050878; GO:0052923; GO:0097269; GO:1990234 38658 XM_029346000.2 0 0 0 0 307 P53804 1.14e-41 E3 ubiquitin-protein ligase TTC3 (EC 2.3.2.27) (Protein DCRR1) (RING finger protein 105) (RING-type E3 ubiquitin transferase TTC3) (TPR repeat protein D) (Tetratricopeptide repeat protein 3) (TPR repeat protein 3) Homo sapiens (Human) protein K48-linked ubiquitination [GO:0070936]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004842; GO:0005634; GO:0005654; GO:0005730; GO:0005794; GO:0005829; GO:0006511; GO:0046872; GO:0070936 38659 XM_044307792.1 0 0 38 31 57 Q0VFM0 1.42e-83 Zinc finger protein-like 1 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) vesicle-mediated transport [GO:0016192] GO:0005794; GO:0016020; GO:0016192; GO:0046872 38660 XM_044322319.1 65 23 47 60 98 NA NA NA NA NA NA 38661 XM_029329486.2 28 22 22 181 14 NA NA NA NA NA NA 38662 XM_044328299.1 0 0 10 0 0 Q6NVC5 0 Mitochondrial Rho GTPase 1-A (MIRO-1-A) (EC 3.6.5.-) (Ras homolog gene family member T1-A) Danio rerio (Zebrafish) (Brachydanio rerio) cellular homeostasis [GO:0019725]; mitochondrial outer membrane permeabilization [GO:0097345]; mitochondrion organization [GO:0007005]; mitochondrion transport along microtubule [GO:0047497]; regulation of mitochondrion organization [GO:0010821]; small GTPase mediated signal transduction [GO:0007264] GO:0003924; GO:0005509; GO:0005525; GO:0005739; GO:0005741; GO:0007005; GO:0007264; GO:0010821; GO:0019725; GO:0047497; GO:0097345 38663 XM_044317764.1 9 7 0 14 4 P06760 9.04e-102 Beta-glucuronidase (EC 3.2.1.31) Rattus norvegicus (Rat) carbohydrate metabolic process [GO:0005975]; chondroitin sulfate catabolic process [GO:0030207]; glucuronoside catabolic process [GO:0019391]; heparan sulfate proteoglycan catabolic process [GO:0030200]; hyaluronan catabolic process [GO:0030214] GO:0004566; GO:0005102; GO:0005615; GO:0005764; GO:0005975; GO:0016787; GO:0019391; GO:0019904; GO:0030200; GO:0030207; GO:0030214; GO:0030246; GO:0043202 38664 XM_044308850.1 38 43 33 22 41 NA NA NA NA NA NA 38665 XM_029325560.2 169 224 189 383 421 D3ZG27 3.66e-92 UbiA prenyltransferase domain-containing protein 1 (EC 2.5.1.-) (EC 2.5.1.39) Rattus norvegicus (Rat) circulatory system development [GO:0072359]; endothelial cell development [GO:0001885]; menaquinone biosynthetic process [GO:0009234]; ubiquinone biosynthetic process [GO:0006744]; ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate [GO:0032194]; vitamin K biosynthetic process [GO:0042371] GO:0000139; GO:0001885; GO:0002083; GO:0004659; GO:0005634; GO:0005737; GO:0005783; GO:0005789; GO:0006744; GO:0009234; GO:0016020; GO:0016209; GO:0031966; GO:0032194; GO:0042371; GO:0072359 38666 XM_029339593.2 2276 3160 694 2211 1149 NA NA NA NA NA NA 38667 XM_044311482.1 301 54 51 132 88 NA NA NA NA NA NA 38668 XM_044307865.1 2 6 20 1004 561 NA NA NA NA NA NA 38669 XM_029337725.2 478 497 474 563 661 NA NA NA NA NA NA 38670 XM_044318172.1 10686 11677 7017 13150 11768 Q9JKM7 4.46e-100 Ras-related protein Rab-37 Mus musculus (Mouse) protein transport [GO:0015031] GO:0003924; GO:0005525; GO:0005768; GO:0005793; GO:0005794; GO:0015031; GO:0030141 38671 XM_029331904.2 1052 1218 472 1075 911 Q9UBQ7 3.13e-109 Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79) (EC 1.1.1.81) Homo sapiens (Human) carboxylic acid metabolic process [GO:0019752]; dicarboxylic acid metabolic process [GO:0043648]; glyoxylate metabolic process [GO:0046487] GO:0005737; GO:0005782; GO:0005829; GO:0008465; GO:0016618; GO:0019752; GO:0030267; GO:0031406; GO:0042803; GO:0043648; GO:0046487; GO:0051287; GO:0070062; GO:0070402; GO:1902494 38672 XM_029324669.2 821 1038 718 1475 1269 NA NA NA NA NA NA 38673 XM_029342621.2 6 0 1 1 37 NA NA NA NA NA NA 38674 XM_029356250.2 100 39 39 88 133 NA NA NA NA NA NA 38675 XM_029329943.2 219 175 82 129 56 P17971 9.3e-89 Potassium voltage-gated channel protein Shal (Shaker cognate l) (Shal2) Drosophila melanogaster (Fruit fly) associative learning [GO:0008306]; chemical synaptic transmission [GO:0007268]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005250; GO:0005886; GO:0006813; GO:0007268; GO:0008076; GO:0008306; GO:0016020; GO:0030425; GO:0034765; GO:0043204; GO:0045202; GO:0051260; GO:0071805 38676 XM_044323455.1 117 140 203 131 100 NA NA NA NA NA NA 38677 XM_029341528.2 0 0 288 177 0 NA NA NA NA NA NA 38678 XM_029358245.2 2557 2337 1347 2148 2316 Q08DB5 1.03e-101 Syntaxin-5 Bos taurus (Bovine) early endosome to Golgi transport [GO:0034498]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi disassembly [GO:0090166]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; regulation of Golgi organization [GO:1903358]; vesicle docking [GO:0048278]; vesicle fusion [GO:0006906] GO:0000139; GO:0000149; GO:0005484; GO:0005829; GO:0006886; GO:0006888; GO:0006906; GO:0012505; GO:0016020; GO:0031201; GO:0031982; GO:0033116; GO:0034498; GO:0045732; GO:0047485; GO:0048278; GO:0090166; GO:1903358 38679 XM_029333358.2 1 0 0 0 18 NA NA NA NA NA NA 38680 XM_044322804.1 204 39 130 0 5 Q13591 1.03e-71 Semaphorin-5A (Semaphorin-F) (Sema F) Homo sapiens (Human) axon extension [GO:0048675]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell-cell signaling [GO:0007267]; diencephalon development [GO:0021536]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of cell adhesion [GO:0007162]; negative regulation of endothelial cell apoptotic process [GO:2000352]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; positive chemotaxis [GO:0050918]; positive regulation of actin filament depolymerization [GO:0030836]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein kinase B signaling [GO:0051897]; semaphorin-plexin signaling pathway [GO:0071526]; signal clustering [GO:1990256] GO:0001755; GO:0001938; GO:0002043; GO:0005886; GO:0007155; GO:0007162; GO:0007267; GO:0007399; GO:0007411; GO:0007413; GO:0016020; GO:0021536; GO:0030215; GO:0030335; GO:0030836; GO:0035373; GO:0043395; GO:0045499; GO:0045545; GO:0045766; GO:0048675; GO:0048842; GO:0048843; GO:0050918; GO:0051897; GO:0060326; GO:0070062; GO:0071526; GO:0090263; GO:1990256; GO:2000352; GO:2001028 38681 XM_044322527.1 220 167 186 402 325 NA NA NA NA NA NA 38682 XM_029330307.2 25 11 0 11 18 Q5ZLS8 1.26e-103 Integrator complex subunit 10 (Int10) Gallus gallus (Chicken) snRNA processing [GO:0016180] GO:0016180; GO:0032039 38683 XM_029330613.2 571 2062 595 7299 10880 NA NA NA NA NA NA 38684 XM_044309136.1 251 762 26 37 34 NA NA NA NA NA NA 38685 XM_029337068.2 26 1 7 15 21 NA NA NA NA NA NA 38686 XM_044308770.1 226 227 337 703 301 Q0KIA2 1.77e-52 PP2C-like domain-containing protein CG9801 Drosophila melanogaster (Fruit fly) NA NA 38687 XM_044313480.1 428 224 114 252 426 A7YWP4 0 Histidine ammonia-lyase (Histidase) (EC 4.3.1.3) Bos taurus (Bovine) histidine catabolic process [GO:0006548]; histidine catabolic process to glutamate and formamide [GO:0019556]; histidine catabolic process to glutamate and formate [GO:0019557] GO:0004397; GO:0005737; GO:0006548; GO:0016841; GO:0019556; GO:0019557 38688 XR_006395829.1 23 0 12 7 80 NA NA NA NA NA NA 38689 XM_044328268.1 0 91 0 0 0 Q7Z6G8 3.63e-73 Ankyrin repeat and sterile alpha motif domain-containing protein 1B (Amyloid-beta protein intracellular domain-associated protein 1) (AIDA-1) (E2A-PBX1-associated protein) (EB-1) Homo sapiens (Human) ephrin receptor signaling pathway [GO:0048013] GO:0005654; GO:0005813; GO:0005829; GO:0005886; GO:0014069; GO:0015030; GO:0043197; GO:0046875; GO:0048013 38690 XM_044328268.1 0 91 0 0 0 Q7Z6G8 1.25e-70 Ankyrin repeat and sterile alpha motif domain-containing protein 1B (Amyloid-beta protein intracellular domain-associated protein 1) (AIDA-1) (E2A-PBX1-associated protein) (EB-1) Homo sapiens (Human) ephrin receptor signaling pathway [GO:0048013] GO:0005654; GO:0005813; GO:0005829; GO:0005886; GO:0014069; GO:0015030; GO:0043197; GO:0046875; GO:0048013 38691 XR_006393282.1 84 10 36 31 50 NA NA NA NA NA NA 38692 XM_029334730.2 1863 1477 1305 2382 1516 P42768 3.43e-56 Actin nucleation-promoting factor WAS (Wiskott-Aldrich syndrome protein) (WASp) Homo sapiens (Human) actin filament polymerization [GO:0030041]; actin filament-based movement [GO:0030048]; actin polymerization or depolymerization [GO:0008154]; blood coagulation [GO:0007596]; Cdc42 protein signal transduction [GO:0032488]; cellular response to type II interferon [GO:0071346]; defense response [GO:0006952]; endosomal transport [GO:0016197]; epidermis development [GO:0008544]; immune response [GO:0006955]; negative regulation of cell motility [GO:2000146]; negative regulation of stress fiber assembly [GO:0051497]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein-containing complex assembly [GO:0065003]; regulation of actin polymerization or depolymerization [GO:0008064]; regulation of lamellipodium assembly [GO:0010591]; regulation of stress fiber assembly [GO:0051492]; regulation of T cell antigen processing and presentation [GO:0002625]; T cell activation [GO:0042110] GO:0002625; GO:0003779; GO:0005634; GO:0005829; GO:0005884; GO:0005886; GO:0005911; GO:0006952; GO:0006955; GO:0007596; GO:0008064; GO:0008154; GO:0008544; GO:0010591; GO:0012506; GO:0015629; GO:0016197; GO:0017124; GO:0019901; GO:0030041; GO:0030048; GO:0030695; GO:0031267; GO:0032488; GO:0035861; GO:0042110; GO:0042802; GO:0043274; GO:0045335; GO:0045944; GO:0051492; GO:0051497; GO:0065003; GO:0070062; GO:0071346; GO:1905168; GO:2000146 38693 XM_029326600.2 17 5 1 0 3 NA NA NA NA NA NA 38694 XM_044314760.1 22 19 53 27 146 NA NA NA NA NA NA 38695 XM_044315157.1 93 323 46 540 138 NA NA NA NA NA NA 38696 XM_044318091.1 65 0 19 0 23 NA NA NA NA NA NA 38697 XR_006394693.1 0 0 101 30 0 NA NA NA NA NA NA 38698 XM_044325622.1 1183 953 819 794 724 NA NA NA NA NA NA 38699 XM_029341337.2 35 83 0 59 0 NA NA NA NA NA NA 38700 XM_044324689.1 297 153 129 105 427 Q96RW7 1.94e-47 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 38701 XM_044324689.1 297 153 129 105 427 Q96RW7 1.8e-44 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 38702 XM_044324689.1 297 153 129 105 427 Q96RW7 5.52e-44 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 38703 XM_044324689.1 297 153 129 105 427 Q96RW7 6.71e-44 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 38704 XM_044324689.1 297 153 129 105 427 Q96RW7 3.84e-40 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 38705 XM_044324689.1 297 153 129 105 427 Q96RW7 2.64e-39 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 38706 XM_044324689.1 297 153 129 105 427 Q96RW7 4.82e-39 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 38707 XM_044324689.1 297 153 129 105 427 Q96RW7 8.34e-39 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 38708 XM_044324689.1 297 153 129 105 427 Q96RW7 2.28e-37 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 38709 XM_044324689.1 297 153 129 105 427 Q96RW7 4.25e-37 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 38710 XM_044324689.1 297 153 129 105 427 Q96RW7 1.9e-36 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 38711 XM_044324689.1 297 153 129 105 427 Q96RW7 7.98e-36 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 38712 XM_044324689.1 297 153 129 105 427 Q96RW7 3.59e-35 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 38713 XM_044324689.1 297 153 129 105 427 Q96RW7 6.17e-35 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 38714 XM_044324689.1 297 153 129 105 427 Q96RW7 9.78e-33 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 38715 XM_044324689.1 297 153 129 105 427 Q96RW7 1.09e-31 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 38716 XM_044324689.1 297 153 129 105 427 Q96RW7 1.09e-30 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 38717 XM_044324689.1 297 153 129 105 427 Q96RW7 3.06e-30 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 38718 XM_044324689.1 297 153 129 105 427 Q96RW7 4.75e-28 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 38719 XM_044324689.1 297 153 129 105 427 Q96RW7 1.6e-26 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 38720 XM_044324689.1 297 153 129 105 427 Q96RW7 5.62e-26 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 38721 XM_044326314.1 665 982 444 609 759 NA NA NA NA NA NA 38722 XM_029332781.2 2449 2247 1484 2390 2144 Q9NXL6 0 SID1 transmembrane family member 1 Homo sapiens (Human) RNA transport [GO:0050658] GO:0003725; GO:0005764; GO:0005886; GO:0015485; GO:0050658; GO:0051033 38723 XM_029336950.2 1 13 5 13 15 NA NA NA NA NA NA 38724 XM_044324081.1 0 1 0 6 1 NA NA NA NA NA NA 38725 XM_029328920.2 1113 940 768 1100 953 Q6YC49 1.36e-132 UDP-N-acetylglucosamine transporter (Golgi UDP-GlcNAc transporter) (Solute carrier family 35 member A3) Bos taurus (Bovine) carbohydrate transport [GO:0008643]; UDP-N-acetylglucosamine transmembrane transport [GO:1990569] GO:0000139; GO:0005459; GO:0008643; GO:1990569 38726 XM_029351760.2 206 198 69 163 148 Q5E9C0 2.73e-96 Ras suppressor protein 1 (Rsu-1) Bos taurus (Bovine) NA NA 38727 XM_029343968.2 10 17 9 59 60 NA NA NA NA NA NA 38728 XM_029357081.2 418 288 0 407 394 NA NA NA NA NA NA 38729 XM_044307260.1 502 252 214 234 723 Q642T7 1.64e-143 U3 small nucleolar RNA-associated protein 25 homolog (Digestive organ expansion factor homolog) (UTP25 small subunit processor component) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) digestive tract morphogenesis [GO:0048546]; embryonic organ development [GO:0048568]; exocrine pancreas development [GO:0031017]; inflammatory response to wounding [GO:0090594]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; organ growth [GO:0035265]; protein catabolic process [GO:0030163]; protein destabilization [GO:0031648]; protein localization to nucleolus [GO:1902570]; sympathetic nervous system development [GO:0048485] GO:0000462; GO:0005730; GO:0030163; GO:0031017; GO:0031648; GO:0034511; GO:0035265; GO:0048485; GO:0048546; GO:0048568; GO:0090594; GO:1902570 38730 XR_006397871.1 56 53 40 86 25 NA NA NA NA NA NA 38731 XR_006395226.1 84 23 15 17 40 NA NA NA NA NA NA 38732 XR_006397923.1 12 1 0 10 2 NA NA NA NA NA NA 38733 XM_029345678.2 29746 25403 15980 17098 16570 Q9C0D7 3.49e-86 Probable ribonuclease ZC3H12C (EC 3.1.-.-) (MCP-induced protein 3) (Zinc finger CCCH domain-containing protein 12C) Homo sapiens (Human) RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502] GO:0003729; GO:0004521; GO:0005634; GO:0036464; GO:0046872; GO:0090502 38734 XM_044323232.1 0 28 28 23 82 Q9UNS1 0 Protein timeless homolog (hTIM) Homo sapiens (Human) branching morphogenesis of an epithelial tube [GO:0048754]; cell cycle phase transition [GO:0044770]; cell division [GO:0051301]; cellular response to bleomycin [GO:1904976]; cellular response to cisplatin [GO:0072719]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hydroxyurea [GO:0072711]; circadian rhythm [GO:0007623]; detection of abiotic stimulus [GO:0009582]; DNA repair [GO:0006281]; DNA replication checkpoint signaling [GO:0000076]; lung development [GO:0030324]; morphogenesis of an epithelium [GO:0002009]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; regulation of circadian rhythm [GO:0042752]; replication fork arrest [GO:0043111]; replication fork protection [GO:0048478] GO:0000076; GO:0000785; GO:0002009; GO:0003677; GO:0005634; GO:0005654; GO:0006281; GO:0006974; GO:0007623; GO:0009582; GO:0030324; GO:0031298; GO:0035861; GO:0042752; GO:0042802; GO:0043111; GO:0044770; GO:0045892; GO:0048478; GO:0048754; GO:0051301; GO:0072711; GO:0072719; GO:1904976; GO:1905168; GO:2000781 38735 XM_029357259.2 100 54 76 95 27 NA NA NA NA NA NA 38736 XM_029339838.2 70 17 2 63 39 Q460N3 3.83e-47 Protein mono-ADP-ribosyltransferase PARP15 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 7) (ARTD7) (B-aggressive lymphoma protein 3) (Poly [ADP-ribose] polymerase 15) (PARP-15) Homo sapiens (Human) negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein poly-ADP-ribosylation [GO:0070212] GO:0000122; GO:0003714; GO:0003950; GO:0005634; GO:0005737; GO:0010629; GO:0016779; GO:0070212; GO:0070403; GO:1990404 38737 XR_006393652.1 51 444 732 274 193 NA NA NA NA NA NA 38738 XM_044311677.1 0 4 0 16 0 B8VIU6 9.59e-57 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 38739 XM_029334069.2 24 0 0 0 0 Q9NTG7 8.86e-121 NAD-dependent protein deacetylase sirtuin-3, mitochondrial (hSIRT3) (EC 2.3.1.286) (Regulatory protein SIR2 homolog 3) (SIR2-like protein 3) Homo sapiens (Human) aerobic respiration [GO:0009060]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of catalase activity [GO:1902553]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of superoxide dismutase activity [GO:1901671]; protein deacetylation [GO:0006476] GO:0005634; GO:0005654; GO:0005739; GO:0005759; GO:0006476; GO:0008270; GO:0009060; GO:0016740; GO:0017136; GO:0032991; GO:0034979; GO:0034983; GO:0043565; GO:0070403; GO:1901671; GO:1902553; GO:2000304 38740 XM_044317349.1 14 0 0 87 0 P0C5E4 1.39e-26 Phosphatidylinositol phosphatase PTPRQ (EC 3.1.3.-) (Receptor-type tyrosine-protein phosphatase Q) (PTP-RQ) (R-PTP-Q) (EC 3.1.3.48) Mus musculus (Mouse) detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; hematopoietic progenitor cell differentiation [GO:0002244]; inner ear morphogenesis [GO:0042472]; neuromuscular process controlling balance [GO:0050885]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; regulation of fat cell differentiation [GO:0045598]; vestibular receptor cell morphogenesis [GO:0060116] GO:0002244; GO:0004725; GO:0016020; GO:0032421; GO:0042472; GO:0043235; GO:0045598; GO:0050885; GO:0050910; GO:0060116; GO:1990264 38741 XM_044317349.1 14 0 0 87 0 P0C5E4 4.38e-26 Phosphatidylinositol phosphatase PTPRQ (EC 3.1.3.-) (Receptor-type tyrosine-protein phosphatase Q) (PTP-RQ) (R-PTP-Q) (EC 3.1.3.48) Mus musculus (Mouse) detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; hematopoietic progenitor cell differentiation [GO:0002244]; inner ear morphogenesis [GO:0042472]; neuromuscular process controlling balance [GO:0050885]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; regulation of fat cell differentiation [GO:0045598]; vestibular receptor cell morphogenesis [GO:0060116] GO:0002244; GO:0004725; GO:0016020; GO:0032421; GO:0042472; GO:0043235; GO:0045598; GO:0050885; GO:0050910; GO:0060116; GO:1990264 38742 XM_044326659.1 10 0 4 23 0 NA NA NA NA NA NA 38743 XM_029338630.2 0 13 71 67 74 NA NA NA NA NA NA 38744 XM_044321093.1 504 286 271 393 177 Q9NZJ4 0 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 38745 XM_029343260.2 735 592 649 1287 991 O16025 0 Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (AOS) (EC 4.2.1.-) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)] Plexaura homomalla (Black sea rod) arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; lipid oxidation [GO:0034440]; oxylipin biosynthetic process [GO:0031408] GO:0005506; GO:0005737; GO:0006633; GO:0009978; GO:0016020; GO:0019369; GO:0020037; GO:0031408; GO:0034440; GO:0047677 38746 XR_006397286.1 34 25 14 48 102 Q95SX7 2.88e-31 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 38747 XM_029356161.2 338 359 359 207 258 Q7ZWG6 1.79e-59 Proton-coupled folate transporter (Solute carrier family 46 member 1) Danio rerio (Zebrafish) (Brachydanio rerio) transmembrane transport [GO:0055085] GO:0005542; GO:0005768; GO:0005886; GO:0010008; GO:0015293; GO:0015350; GO:0016020; GO:0016323; GO:0016324; GO:0022857; GO:0055085 38748 XM_044320508.1 19 20 0 0 47 NA NA NA NA NA NA 38749 XR_006394059.1 248 353 0 431 330 NA NA NA NA NA NA 38750 XM_044313184.1 128 0 172 2 3 NA NA NA NA NA NA 38751 XM_029332931.2 160 91 68 92 70 P62262 7.84e-95 14-3-3 protein epsilon (14-3-3E) (Protein kinase C inhibitor protein 1) (KCIP-1) Ovis aries (Sheep) cellular response to heat [GO:0034605]; MAPK cascade [GO:0000165]; positive regulation of protein export from nucleus [GO:0046827]; protein localization to nucleus [GO:0034504] GO:0000165; GO:0005634; GO:0005737; GO:0034504; GO:0034605; GO:0042470; GO:0046827 38752 XM_044308804.1 263 130 160 178 304 NA NA NA NA NA NA 38753 XM_029333497.2 85 0 0 0 75 Q1PSW8 7.16e-24 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (mLin41) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Mus musculus (Mouse) 3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to organic substance [GO:0071310]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA processing [GO:0035196]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; post-transcriptional regulation of gene expression [GO:0010608]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein metabolic process [GO:0051246]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0001843; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0010608; GO:0017148; GO:0021915; GO:0030371; GO:0035196; GO:0035198; GO:0035278; GO:0043161; GO:0051246; GO:0051865; GO:0060964; GO:0061158; GO:0061630; GO:0071310; GO:0072089; GO:2000177; GO:2000637 38754 XM_044310312.1 143 95 12 25 16 NA NA NA NA NA NA 38755 XM_029332251.2 173 732 138 140 332 Q9BX70 2.81e-61 BTB/POZ domain-containing protein 2 Homo sapiens (Human) neurogenesis [GO:0022008] GO:0000932; GO:0005829; GO:0022008 38756 XR_006392843.1 11 19 0 0 31 NA NA NA NA NA NA 38757 XM_029332000.2 262 312 267 417 302 Q0P5B7 6.06e-53 Arylacetamide deacetylase (EC 3.1.1.3) Bos taurus (Bovine) lipid metabolic process [GO:0006629]; positive regulation of triglyceride catabolic process [GO:0010898] GO:0004806; GO:0005789; GO:0006629; GO:0010898; GO:0017171 38758 XM_044318231.1 143 150 53 103 157 O88866 7.44e-51 Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (Serine/threonine-protein kinase MAK-V) Mus musculus (Mouse) intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468] GO:0004672; GO:0004674; GO:0005524; GO:0006468; GO:0035556; GO:0106310 38759 XM_029340181.2 694 305 309 93 23 A8DZE6 9.53e-59 Wilms tumor protein 1-interacting protein homolog (WT1-interacting protein homolog) Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; cloaca development [GO:0035844]; cytoskeleton organization [GO:0007010]; determination of heart left/right asymmetry [GO:0061371]; determination of left/right asymmetry in lateral mesoderm [GO:0003140]; establishment of mitotic spindle orientation [GO:0000132]; heart looping [GO:0001947]; negative regulation of hippo signaling [GO:0035331]; neural crest cell development [GO:0014032]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; regulation of cell morphogenesis [GO:0022604]; regulation of DNA-templated transcription [GO:0006355]; response to hypoxia [GO:0001666]; visceral serous pericardium development [GO:0061032] GO:0000132; GO:0000932; GO:0001666; GO:0001947; GO:0003140; GO:0003714; GO:0005634; GO:0005667; GO:0005912; GO:0006355; GO:0007010; GO:0014032; GO:0022604; GO:0035331; GO:0035844; GO:0036064; GO:0046872; GO:0060271; GO:0061032; GO:0061371; GO:2000637 38760 XM_044323874.1 11 0 27 0 89 NA NA NA NA NA NA 38761 XM_044315552.1 0 9 31 6 39 NA NA NA NA NA NA 38762 XM_044308441.1 84 70 44 107 86 Q5SX19 1.61e-48 N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase (EC 3.5.1.89) (Phosphatidylinositol-glycan biosynthesis class L protein) (PIG-L) Mus musculus (Mouse) GPI anchor biosynthetic process [GO:0006506] GO:0000225; GO:0005783; GO:0005789; GO:0006506; GO:0016811 38763 XM_044325026.1 0 0 0 4 74 NA NA NA NA NA NA 38764 XM_044311322.1 4 0 1 3 28 NA NA NA NA NA NA 38765 XR_003825378.2 147 16641 139 6692 8154 NA NA NA NA NA NA 38766 XM_029329518.2 38 52 0 77 156 O70521 7.51e-32 Regulator of G-protein signaling 19 (RGS19) (G-alpha-interacting protein) (GAIP) Rattus norvegicus (Rat) negative regulation of signal transduction [GO:0009968]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; response to ethanol [GO:0045471] GO:0000139; GO:0001965; GO:0005096; GO:0005737; GO:0005903; GO:0008277; GO:0009968; GO:0016020; GO:0030136; GO:0045121; GO:0045471 38767 XM_044317027.1 6 2 3 9 0 Q9IAT6 1.98e-30 Delta-like protein C (DeltaC) (delC) Danio rerio (Zebrafish) (Brachydanio rerio) arterial endothelial cell differentiation [GO:0060842]; blood vessel morphogenesis [GO:0048514]; dorsal aorta development [GO:0035907]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; negative regulation of Notch signaling pathway [GO:0045746]; neuron development [GO:0048666]; Notch signaling pathway [GO:0007219]; sclerotome development [GO:0061056]; somite specification [GO:0001757]; somitogenesis [GO:0001756]; ventral spinal cord interneuron differentiation [GO:0021514] GO:0001756; GO:0001757; GO:0002244; GO:0005112; GO:0005509; GO:0005737; GO:0005886; GO:0007219; GO:0021514; GO:0030165; GO:0035907; GO:0042802; GO:0045746; GO:0048471; GO:0048514; GO:0048666; GO:0060218; GO:0060842; GO:0061056 38768 XM_044317027.1 6 2 3 9 0 Q9IAT6 1.49e-24 Delta-like protein C (DeltaC) (delC) Danio rerio (Zebrafish) (Brachydanio rerio) arterial endothelial cell differentiation [GO:0060842]; blood vessel morphogenesis [GO:0048514]; dorsal aorta development [GO:0035907]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; negative regulation of Notch signaling pathway [GO:0045746]; neuron development [GO:0048666]; Notch signaling pathway [GO:0007219]; sclerotome development [GO:0061056]; somite specification [GO:0001757]; somitogenesis [GO:0001756]; ventral spinal cord interneuron differentiation [GO:0021514] GO:0001756; GO:0001757; GO:0002244; GO:0005112; GO:0005509; GO:0005737; GO:0005886; GO:0007219; GO:0021514; GO:0030165; GO:0035907; GO:0042802; GO:0045746; GO:0048471; GO:0048514; GO:0048666; GO:0060218; GO:0060842; GO:0061056 38769 XM_044317198.1 0 11 0 0 0 Q4G0X4 3.93e-32 BTB/POZ domain-containing protein KCTD21 (KCASH2 protein) (Potassium channel tetramerization domain-containing protein 21) Homo sapiens (Human) negative regulation of smoothened signaling pathway [GO:0045879]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0006511; GO:0016567; GO:0042802; GO:0042826; GO:0045879; GO:0051260; GO:0097602 38770 XM_029339439.2 3 5 18 12 57 NA NA NA NA NA NA 38771 XM_029351852.2 1131 1141 558 928 861 P29084 3.69e-64 Transcription initiation factor IIE subunit beta (TFIIE-beta) (General transcription factor IIE subunit 2) Homo sapiens (Human) transcription by RNA polymerase II [GO:0006366]; transcription initiation at RNA polymerase II promoter [GO:0006367] GO:0003677; GO:0003723; GO:0005654; GO:0005669; GO:0005673; GO:0005829; GO:0006366; GO:0006367; GO:0016251; GO:0016607 38772 XM_029335918.2 279 240 175 294 902 Q1LZF2 0 Actin-related protein 8 Bos taurus (Bovine) cell cycle [GO:0007049]; cell division [GO:0051301]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; regulation of DNA-templated transcription [GO:0006355] GO:0005524; GO:0006302; GO:0006310; GO:0006355; GO:0007049; GO:0031011; GO:0051301 38773 XM_044328505.1 167 56 153 185 320 Q9BX70 7.88e-68 BTB/POZ domain-containing protein 2 Homo sapiens (Human) neurogenesis [GO:0022008] GO:0000932; GO:0005829; GO:0022008 38774 XM_029325044.2 155 134 112 313 297 NA NA NA NA NA NA 38775 XM_044309146.1 46 17 66 18 104 Q99741 1.37e-132 Cell division control protein 6 homolog (CDC6-related protein) (Cdc18-related protein) (HsCdc18) (p62(cdc6)) (HsCDC6) Homo sapiens (Human) cell division [GO:0051301]; cellular response to angiotensin [GO:1904385]; cellular response to vasopressin [GO:1904117]; DNA replication checkpoint signaling [GO:0000076]; DNA replication initiation [GO:0006270]; mitotic cell cycle [GO:0000278]; mitotic DNA replication checkpoint signaling [GO:0033314]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; positive regulation of chromosome segregation [GO:0051984]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytokinesis [GO:0032467]; positive regulation of fibroblast proliferation [GO:0048146]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; traversing start control point of mitotic cell cycle [GO:0007089] GO:0000076; GO:0000079; GO:0000166; GO:0000278; GO:0000922; GO:0003688; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006270; GO:0007089; GO:0008156; GO:0008285; GO:0019900; GO:0030071; GO:0032467; GO:0033314; GO:0045171; GO:0045737; GO:0048146; GO:0051233; GO:0051301; GO:0051984; GO:0072686; GO:1904117; GO:1904385 38776 XM_029349314.2 24 55 63 115 195 Q15075 3.85e-50 Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2) Homo sapiens (Human) chemical synaptic transmission, postsynaptic [GO:0099565]; early endosome to late endosome transport [GO:0045022]; endocytosis [GO:0006897]; modulation by host of viral process [GO:0044788]; synaptic vesicle to endosome fusion [GO:0016189]; vesicle fusion [GO:0006906] GO:0005516; GO:0005545; GO:0005737; GO:0005769; GO:0005829; GO:0005969; GO:0006897; GO:0006906; GO:0008270; GO:0016020; GO:0016189; GO:0019897; GO:0030742; GO:0031901; GO:0042803; GO:0044308; GO:0044788; GO:0045022; GO:0070062; GO:0098685; GO:0098794; GO:0098978; GO:0099565 38777 XM_029333166.2 8 0 55 26 171 Q9HAD4 1.79e-58 WD repeat-containing protein 41 Homo sapiens (Human) autophagy [GO:0006914]; negative regulation of exocytosis [GO:0045920]; negative regulation of immune response [GO:0050777]; positive regulation of GTPase activity [GO:0043547]; regulation of autophagy [GO:0010506] GO:0005737; GO:0005765; GO:0006914; GO:0010506; GO:0032045; GO:0043547; GO:0045920; GO:0050777 38778 XM_044323482.1 60 1323 1599 1826 2058 F1NWE3 0 Receptor-type tyrosine-protein phosphatase S (R-PTP-S) (EC 3.1.3.48) (Chick receptor tyrosine phosphatase alpha) (CRYP alpha) (CRYPalpha) Gallus gallus (Chicken) negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; synaptic membrane adhesion [GO:0099560] GO:0004725; GO:0005886; GO:0006470; GO:0008201; GO:0030424; GO:0030426; GO:0030517; GO:0030672; GO:0035335; GO:0042803; GO:0043204; GO:0043395; GO:0048671; GO:0048681; GO:0061000; GO:0098839; GO:0099560 38779 XM_044323482.1 60 1323 1599 1826 2058 F1NWE3 1.39e-23 Receptor-type tyrosine-protein phosphatase S (R-PTP-S) (EC 3.1.3.48) (Chick receptor tyrosine phosphatase alpha) (CRYP alpha) (CRYPalpha) Gallus gallus (Chicken) negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; synaptic membrane adhesion [GO:0099560] GO:0004725; GO:0005886; GO:0006470; GO:0008201; GO:0030424; GO:0030426; GO:0030517; GO:0030672; GO:0035335; GO:0042803; GO:0043204; GO:0043395; GO:0048671; GO:0048681; GO:0061000; GO:0098839; GO:0099560 38780 XM_044323482.1 60 1323 1599 1826 2058 F1NWE3 7.05e-23 Receptor-type tyrosine-protein phosphatase S (R-PTP-S) (EC 3.1.3.48) (Chick receptor tyrosine phosphatase alpha) (CRYP alpha) (CRYPalpha) Gallus gallus (Chicken) negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; synaptic membrane adhesion [GO:0099560] GO:0004725; GO:0005886; GO:0006470; GO:0008201; GO:0030424; GO:0030426; GO:0030517; GO:0030672; GO:0035335; GO:0042803; GO:0043204; GO:0043395; GO:0048671; GO:0048681; GO:0061000; GO:0098839; GO:0099560 38781 XM_029358557.2 1222 817 932 905 1141 Q9P232 6.55e-73 Contactin-3 (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein) Homo sapiens (Human) cell adhesion [GO:0007155] GO:0005576; GO:0005886; GO:0007155; GO:0043005 38782 XM_029358557.2 1222 817 932 905 1141 Q9P232 2.1e-21 Contactin-3 (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein) Homo sapiens (Human) cell adhesion [GO:0007155] GO:0005576; GO:0005886; GO:0007155; GO:0043005 38783 XR_006397932.1 3 9 0 8 22 NA NA NA NA NA NA 38784 XM_029346761.2 220 177 12 156 374 NA NA NA NA NA NA 38785 XR_006392118.1 88 92 62 62 103 NA NA NA NA NA NA 38786 XM_029358295.2 233 220 27 52 231 Q6DJ06 4.39e-54 LIM domain transcription factor LMO4.2 (LIM domain only protein 4.2) (LMO-4.2) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell differentiation [GO:0030154]; gastrulation [GO:0007369]; mesoderm development [GO:0007498]; negative regulation of neuron differentiation [GO:0045665]; nervous system development [GO:0007399]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0003712; GO:0007369; GO:0007399; GO:0007498; GO:0030154; GO:0045665; GO:0045944; GO:0046872 38787 XM_029350394.2 504 345 263 377 380 Q6GPV5 2.12e-41 E3 ubiquitin-protein ligase RNF181 (EC 2.3.2.27) (RING finger protein 181) Xenopus laevis (African clawed frog) NA GO:0046872; GO:0061630 38788 XM_044322031.1 223 154 156 88 73 NA NA NA NA NA NA 38789 XM_044319566.1 10 0 19 19 139 P71359 1.73e-31 ATP-dependent DNA helicase RecQ (EC 3.6.4.12) Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; SOS response [GO:0009432] GO:0003677; GO:0005524; GO:0005694; GO:0005737; GO:0006260; GO:0006281; GO:0006310; GO:0009378; GO:0009432; GO:0016887; GO:0030894; GO:0032508; GO:0043138; GO:0043590 38790 XM_044326436.1 0 0 0 4 20 NA NA NA NA NA NA 38791 XR_006395205.1 18 6 7 23 10 NA NA NA NA NA NA 38792 XR_006393829.1 16 0 12 0 37 NA NA NA NA NA NA 38793 XM_044325833.1 13 43 1 4 29 NA NA NA NA NA NA 38794 XM_044327232.1 29 2 12 22 8 Q96RW7 1.25e-25 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 38795 XM_029333679.2 819 168 662 686 119 Q3ZC91 3.11e-39 Acid sphingomyelinase-like phosphodiesterase 3a (ASM-like phosphodiesterase 3a) (EC 3.1.4.-) Bos taurus (Bovine) nucleoside triphosphate catabolic process [GO:0009143] GO:0005576; GO:0005615; GO:0008081; GO:0008270; GO:0009143 38796 XM_044320164.1 398 188 236 410 435 Q9HC29 3.1e-26 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) (Inflammatory bowel disease protein 1) Homo sapiens (Human) biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gamma-delta T cell activation [GO:0046645]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0002221; GO:0002227; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005739; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006965; GO:0007249; GO:0007254; GO:0007584; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031982; GO:0032088; GO:0032495; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043552; GO:0044877; GO:0045087; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0046645; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050871; GO:0051092; GO:0051353; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 38797 XM_044314420.1 277 178 147 129 148 Q3UQ28 2.41e-32 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 38798 XM_044314420.1 277 178 147 129 148 Q3UQ28 1.76e-25 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 38799 XR_006393848.1 7 0 12 0 37 NA NA NA NA NA NA 38800 XM_044308814.1 2 4 3 0 9 NA NA NA NA NA NA 38801 XM_029336854.2 622 457 150 666 435 NA NA NA NA NA NA 38802 XM_029342018.2 1085 651 464 1082 962 Q5U3S1 0 Katanin p60 ATPase-containing subunit A-like 1 (Katanin p60 subunit A-like 1) (EC 5.6.1.1) (p60 katanin-like 1) Danio rerio (Zebrafish) (Brachydanio rerio) microtubule severing [GO:0051013]; spermatogenesis [GO:0007283] GO:0000922; GO:0005524; GO:0005737; GO:0005813; GO:0005819; GO:0005874; GO:0007283; GO:0008017; GO:0008568; GO:0015630; GO:0016853; GO:0016887; GO:0051013 38803 XM_029353766.2 1474 1110 833 1115 1229 NA NA NA NA NA NA 38804 XM_044324885.1 1054 690 551 1066 906 Q5ZIJ9 0 E3 ubiquitin-protein ligase MIB2 (EC 2.3.2.27) (Mind bomb homolog 2) (RING-type E3 ubiquitin transferase MIB2) Gallus gallus (Chicken) Notch signaling pathway [GO:0007219]; protein ubiquitination [GO:0016567] GO:0004842; GO:0005737; GO:0007219; GO:0008270; GO:0016567 38805 XM_044310718.1 73 79 75 99 55 A3KMX0 0 DNA excision repair protein ERCC-6-like 2 (EC 3.6.4.-) Bos taurus (Bovine) DNA repair [GO:0006281] GO:0003677; GO:0004386; GO:0005524; GO:0005634; GO:0005739; GO:0005815; GO:0006281; GO:0016787; GO:0140658 38806 XM_044310718.1 73 79 75 99 55 A3KMX0 2.09e-21 DNA excision repair protein ERCC-6-like 2 (EC 3.6.4.-) Bos taurus (Bovine) DNA repair [GO:0006281] GO:0003677; GO:0004386; GO:0005524; GO:0005634; GO:0005739; GO:0005815; GO:0006281; GO:0016787; GO:0140658 38807 XM_044318469.1 540 356 0 73 83 A5WUL3 5.89e-60 Mediator of RNA polymerase II transcription subunit 22 (Mediator complex subunit 22) (Surfeit locus protein 5) Danio rerio (Zebrafish) (Brachydanio rerio) regulation of transcription by RNA polymerase II [GO:0006357] GO:0003712; GO:0006357; GO:0016592 38808 XM_044316753.1 50 39 11 29 83 NA NA NA NA NA NA 38809 XM_029357616.2 590 459 230 330 469 Q8CGS5 2.37e-146 Zinc phosphodiesterase ELAC protein 2 (EC 3.1.26.11) (ElaC homolog protein 2) (Ribonuclease Z 2) (RNase Z 2) (tRNA 3 endonuclease 2) (tRNase Z 2) Rattus norvegicus (Rat) mitochondrial tRNA 3'-trailer cleavage, endonucleolytic [GO:0072684] GO:0004549; GO:0005634; GO:0005739; GO:0042645; GO:0042781; GO:0046872; GO:0072684 38810 XM_044317798.1 85 109 223 139 484 Q8RWN2 9.88e-53 Protein ZINC INDUCED FACILITATOR 1 Arabidopsis thaliana (Mouse-ear cress) regulation of stomatal closure [GO:0090333]; response to nematode [GO:0009624]; response to zinc ion [GO:0010043]; zinc ion homeostasis [GO:0055069] GO:0005886; GO:0009624; GO:0009705; GO:0010043; GO:0022821; GO:0055069; GO:0090333 38811 XM_044322177.1 164 192 94 38 364 Q91ZV2 8.55e-26 Discoidin, CUB and LCCL domain-containing protein 2 (Endothelial and smooth muscle cell-derived neuropilin-like protein) Rattus norvegicus (Rat) negative regulation of cell growth [GO:0030308]; wound healing [GO:0042060] GO:0005886; GO:0009986; GO:0030308; GO:0038023; GO:0042060 38812 XM_044309756.1 0 0 144 137 0 O75581 0 Low-density lipoprotein receptor-related protein 6 (LRP-6) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; chemical synaptic transmission [GO:0007268]; dopaminergic neuron differentiation [GO:0071542]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001933; GO:0005041; GO:0005102; GO:0005109; GO:0005576; GO:0005783; GO:0005886; GO:0006469; GO:0007204; GO:0007268; GO:0009986; GO:0014029; GO:0014033; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0031410; GO:0031901; GO:0034392; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043434; GO:0044335; GO:0044340; GO:0045121; GO:0045202; GO:0045787; GO:0045893; GO:0045944; GO:0051091; GO:0060070; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072659; GO:0090118; GO:0090244; GO:0098609; GO:1904928; GO:1904948; GO:1904953; GO:1990851; GO:1990909 38813 XM_044309756.1 0 0 144 137 0 O75581 2.95e-170 Low-density lipoprotein receptor-related protein 6 (LRP-6) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; chemical synaptic transmission [GO:0007268]; dopaminergic neuron differentiation [GO:0071542]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001933; GO:0005041; GO:0005102; GO:0005109; GO:0005576; GO:0005783; GO:0005886; GO:0006469; GO:0007204; GO:0007268; GO:0009986; GO:0014029; GO:0014033; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0031410; GO:0031901; GO:0034392; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043434; GO:0044335; GO:0044340; GO:0045121; GO:0045202; GO:0045787; GO:0045893; GO:0045944; GO:0051091; GO:0060070; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072659; GO:0090118; GO:0090244; GO:0098609; GO:1904928; GO:1904948; GO:1904953; GO:1990851; GO:1990909 38814 XM_029349613.2 0 0 17 0 26 Q5RJY2 3.15e-22 G2/M phase-specific E3 ubiquitin-protein ligase (EC 2.3.2.26) (G2/M phase-specific HECT-type E3 ubiquitin transferase) Mus musculus (Mouse) apoptotic process [GO:0006915]; blastocyst development [GO:0001824]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; protein polyubiquitination [GO:0000209] GO:0000209; GO:0001824; GO:0005634; GO:0005730; GO:0005794; GO:0005829; GO:0006915; GO:0043231; GO:0046872; GO:0061630; GO:2001243 38815 XR_006396892.1 20 24 0 0 0 NA NA NA NA NA NA 38816 XM_029333333.2 1654 1510 1210 1125 1748 Q6UW02 2.7e-78 Cytochrome P450 20A1 (EC 1.14.-.-) Homo sapiens (Human) NA GO:0004497; GO:0005506; GO:0016020; GO:0016705; GO:0020037 38817 XR_003827306.2 356 228 163 173 342 Q5F477 8.28e-63 Lipid droplet-associated hydrolase (EC 3.1.1.-) (Lipid droplet-associated serine hydrolase) Gallus gallus (Chicken) lipid storage [GO:0019915] GO:0004771; GO:0005783; GO:0005811; GO:0019915 38818 XM_029333690.2 24 23 24 30 35 NA NA NA NA NA NA 38819 XM_029354413.2 37 13 41 105 39 Q6DHN0 1.57e-31 Transmembrane protein 53 Danio rerio (Zebrafish) (Brachydanio rerio) negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of ossification [GO:0030279]; negative regulation of osteoblast differentiation [GO:0045668]; regulation of nucleocytoplasmic transport [GO:0046822] GO:0005640; GO:0030279; GO:0030514; GO:0031965; GO:0045668; GO:0046822 38820 XM_029323718.2 68 233 33 33 233 P25931 4.95e-28 RYamide receptor (Neuropeptide Y-like receptor) (NPY-R) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218] GO:0001653; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0016020 38821 XM_044307874.1 757 0 203 257 691 Q8IV61 5.07e-135 Ras guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1) Homo sapiens (Human) MAPK cascade [GO:0000165]; positive regulation of GTPase activity [GO:0043547]; Ras protein signal transduction [GO:0007265]; small GTPase mediated signal transduction [GO:0007264] GO:0000165; GO:0005085; GO:0005096; GO:0005509; GO:0005886; GO:0007264; GO:0007265; GO:0019900; GO:0019992; GO:0031267; GO:0032045; GO:0043547; GO:0048471 38822 XM_044325555.1 390 408 72 241 36 NA NA NA NA NA NA 38823 XM_029336414.2 221 103 99 77 247 F1QAM1 2.34e-39 Palmitoyltransferase ZDHHC4 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 4) Danio rerio (Zebrafish) (Brachydanio rerio) peptidyl-L-cysteine S-palmitoylation [GO:0018230]; protein targeting to membrane [GO:0006612] GO:0000139; GO:0005783; GO:0005789; GO:0005794; GO:0005886; GO:0006612; GO:0018230; GO:0019706 38824 XM_044328115.1 854 358 490 673 545 Q9UPZ3 1.64e-54 BLOC-2 complex member HPS5 (Alpha-integrin-binding protein 63) (Hermansky-Pudlak syndrome 5 protein) (Ruby-eye protein 2 homolog) (Ru2) Homo sapiens (Human) blood coagulation [GO:0007596]; developmental pigmentation [GO:0048066]; intracellular transport [GO:0046907]; melanosome assembly [GO:1903232]; platelet dense granule organization [GO:0060155] GO:0005737; GO:0005769; GO:0005829; GO:0007596; GO:0031084; GO:0046907; GO:0048066; GO:0060155; GO:1903232 38825 XM_044328115.1 854 358 490 673 545 Q9UPZ3 2.84e-29 BLOC-2 complex member HPS5 (Alpha-integrin-binding protein 63) (Hermansky-Pudlak syndrome 5 protein) (Ruby-eye protein 2 homolog) (Ru2) Homo sapiens (Human) blood coagulation [GO:0007596]; developmental pigmentation [GO:0048066]; intracellular transport [GO:0046907]; melanosome assembly [GO:1903232]; platelet dense granule organization [GO:0060155] GO:0005737; GO:0005769; GO:0005829; GO:0007596; GO:0031084; GO:0046907; GO:0048066; GO:0060155; GO:1903232 38826 XR_006395000.1 6 153 48 74 34 NA NA NA NA NA NA 38827 XM_029341262.2 37 12 20 0 81 O16025 2.35e-46 Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (AOS) (EC 4.2.1.-) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)] Plexaura homomalla (Black sea rod) arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; lipid oxidation [GO:0034440]; oxylipin biosynthetic process [GO:0031408] GO:0005506; GO:0005737; GO:0006633; GO:0009978; GO:0016020; GO:0019369; GO:0020037; GO:0031408; GO:0034440; GO:0047677 38828 XM_044309797.1 120 0 242 303 18 NA NA NA NA NA NA 38829 XR_003824656.2 30 3 17 5 95 NA NA NA NA NA NA 38830 XR_006393054.1 10 0 28 1 55 NA NA NA NA NA NA 38831 XM_044308328.1 0 0 0 0 222 NA NA NA NA NA NA 38832 XM_044308642.1 617 294 477 423 503 NA NA NA NA NA NA 38833 XM_029342123.2 1738 799 1011 1431 1364 Q14692 0 Ribosome biogenesis protein BMS1 homolog (Ribosome assembly protein BMS1 homolog) Homo sapiens (Human) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000479]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462] GO:0000462; GO:0000479; GO:0003723; GO:0003924; GO:0005524; GO:0005525; GO:0005654; GO:0005694; GO:0005730; GO:0030686; GO:0034511 38834 XM_029342123.2 1738 799 1011 1431 1364 Q14692 1.56e-170 Ribosome biogenesis protein BMS1 homolog (Ribosome assembly protein BMS1 homolog) Homo sapiens (Human) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000479]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462] GO:0000462; GO:0000479; GO:0003723; GO:0003924; GO:0005524; GO:0005525; GO:0005654; GO:0005694; GO:0005730; GO:0030686; GO:0034511 38835 XR_003827238.2 24 2 13 11 6 NA NA NA NA NA NA 38836 XM_044308661.1 139 109 255 55 289 Q96AY4 1.62e-63 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38837 XM_044308661.1 139 109 255 55 289 Q96AY4 9.7e-61 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38838 XM_044308661.1 139 109 255 55 289 Q96AY4 2.89e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38839 XM_044308661.1 139 109 255 55 289 Q96AY4 9.59e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38840 XM_044308661.1 139 109 255 55 289 Q96AY4 5.94e-58 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38841 XM_044308661.1 139 109 255 55 289 Q96AY4 3.52e-52 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38842 XM_044308661.1 139 109 255 55 289 Q96AY4 1.66e-46 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38843 XM_044308661.1 139 109 255 55 289 Q96AY4 9.85e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38844 XM_044308661.1 139 109 255 55 289 Q96AY4 2.22e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38845 XM_029342120.2 1423 346 356 534 553 Q86NP2 3.26e-48 Negative elongation factor A Drosophila melanogaster (Fruit fly) negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription elongation by RNA polymerase II [GO:0034244] GO:0000122; GO:0003723; GO:0005634; GO:0005694; GO:0017053; GO:0032021; GO:0034244 38846 XM_044315509.1 66 74 16 12 14 NA NA NA NA NA NA 38847 XR_006393595.1 12 0 0 0 6 NA NA NA NA NA NA 38848 XM_044309792.1 318 538 255 505 363 NA NA NA NA NA NA 38849 XM_044325564.1 71 31 77 46 50 NA NA NA NA NA NA 38850 XM_044319457.1 13 0 11 0 22 NA NA NA NA NA NA 38851 XM_029345161.2 4934 5699 1771 3939 6635 P29145 7.97e-144 PC3-like endoprotease variant B (EC 3.4.21.-) (SPC3) Hydra vulgaris (Hydra) (Hydra attenuata) proteolysis [GO:0006508] GO:0004252; GO:0006508 38852 XR_006397401.1 0 0 0 14 7 NA NA NA NA NA NA 38853 XR_006396261.1 290 43 21 181 59 NA NA NA NA NA NA 38854 XM_029341677.2 1838 1609 920 1927 1798 Q9Z254 7.73e-99 PDZ domain-containing protein GIPC1 (GAIP C-terminus-interacting protein) (GLUT1 C-terminal-binding protein) (GLUT1CBP) (RGS-GAIP-interacting protein) (RGS19-interacting protein 1) (Synectin) Rattus norvegicus (Rat) cellular response to interleukin-7 [GO:0098761]; chemical synaptic transmission [GO:0007268]; endothelial cell migration [GO:0043542]; glutamate secretion [GO:0014047]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; positive regulation of cytokinesis [GO:0032467]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; protein targeting [GO:0006605]; regulation of protein stability [GO:0031647]; regulation of synaptic plasticity [GO:0048167]; regulation of synaptic vesicle exocytosis [GO:2000300] GO:0003779; GO:0005102; GO:0005737; GO:0005829; GO:0005903; GO:0005938; GO:0006605; GO:0007268; GO:0008021; GO:0012506; GO:0014047; GO:0016020; GO:0017022; GO:0030139; GO:0030165; GO:0030511; GO:0031410; GO:0031647; GO:0032435; GO:0032467; GO:0042802; GO:0043197; GO:0043198; GO:0043542; GO:0048023; GO:0048167; GO:0098685; GO:0098761; GO:0098793; GO:0098794; GO:0098978; GO:0099171; GO:2000300 38855 XM_044310958.1 178 208 101 214 281 NA NA NA NA NA NA 38856 XM_029339669.2 610 552 451 950 720 Q8NB25 4.45e-111 Protein FAM184A Homo sapiens (Human) NA GO:0005615 38857 XM_044314710.1 5 0 4 3 46 NA NA NA NA NA NA 38858 XM_029328621.2 0 0 0 85 0 Q1WK23 1.47e-38 Serine protease 23 (EC 3.4.21.-) Macaca mulatta (Rhesus macaque) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 38859 XR_006396162.1 8 0 2 6 20 NA NA NA NA NA NA 38860 XM_029351982.2 881 497 402 787 798 Q5F364 0 Multidrug resistance-associated protein 1 (EC 7.6.2.2) (ATP-binding cassette sub-family C member 1) (Glutathione-S-conjugate-translocating ATPase ABCC1) (EC 7.6.2.3) (Leukotriene C(4) transporter) (LTC4 transporter) Gallus gallus (Chicken) glutathione transmembrane transport [GO:0034775]; lipid transport [GO:0006869]; transmembrane transport [GO:0055085]; xenobiotic transport [GO:0042908] GO:0005524; GO:0006869; GO:0008559; GO:0016020; GO:0016323; GO:0016887; GO:0034634; GO:0034775; GO:0042626; GO:0042908; GO:0055085 38861 XR_003828485.2 587 192 160 144 331 NA NA NA NA NA NA 38862 XM_044328872.1 1514 575 536 1813 1510 O76840 5.15e-26 Papilin (Abnormal cell migration protein 6) Caenorhabditis elegans cell morphogenesis [GO:0000902]; embryo development ending in birth or egg hatching [GO:0009792]; embryonic morphogenesis [GO:0048598]; extracellular matrix organization [GO:0030198]; multicellular organism reproduction [GO:0032504]; negative regulation of peptidase activity [GO:0010466]; nematode larval development [GO:0002119] GO:0000902; GO:0002119; GO:0004222; GO:0004867; GO:0005576; GO:0005604; GO:0009792; GO:0010466; GO:0030198; GO:0031012; GO:0032504; GO:0048598 38863 XM_029333343.2 0 0 46 40 0 Q8WVS4 9.36e-115 Cytoplasmic dynein 2 intermediate chain 1 (Dynein 2 intermediate chain 1) (WD repeat-containing protein 60) Homo sapiens (Human) cilium assembly [GO:0060271]; embryonic skeletal system morphogenesis [GO:0048704]; intraciliary retrograde transport [GO:0035721]; intraciliary transport [GO:0042073]; microtubule-based movement [GO:0007018] GO:0000242; GO:0005615; GO:0005813; GO:0005868; GO:0005929; GO:0007018; GO:0035721; GO:0042073; GO:0045503; GO:0045504; GO:0048704; GO:0060271; GO:0097014; GO:0097542; GO:0097546 38864 XM_029340480.2 639 381 362 754 576 Q9NXD2 8.33e-68 Myotubularin-related protein 10 (Inactive phosphatidylinositol 3-phosphatase 10) Homo sapiens (Human) phosphatidylinositol dephosphorylation [GO:0046856] GO:0004438; GO:0005737; GO:0005829; GO:0046856 38865 XM_029339009.2 285 312 207 340 423 Q9WVS8 3.63e-143 Mitogen-activated protein kinase 7 (MAP kinase 7) (MAPK 7) (EC 2.7.11.24) (Big MAP kinase 1) (BMK-1) (Extracellular signal-regulated kinase 5) (ERK-5) Mus musculus (Mouse) calcineurin-NFAT signaling cascade [GO:0033173]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cellular response to growth factor stimulus [GO:0071363]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to laminar fluid shear stress [GO:0071499]; cellular response to transforming growth factor beta stimulus [GO:0071560]; ERK5 cascade [GO:0070375]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of response to cytokine stimulus [GO:0060761]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765] GO:0000165; GO:0004672; GO:0004674; GO:0004707; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006468; GO:0007049; GO:0016605; GO:0018105; GO:0030154; GO:0033173; GO:0034115; GO:0035556; GO:0036003; GO:0043066; GO:0045765; GO:0045944; GO:0046777; GO:0051019; GO:0051247; GO:0060761; GO:0070301; GO:0070375; GO:0070885; GO:0071363; GO:0071499; GO:0071560; GO:0106310; GO:1902176; GO:2000352; GO:2001240 38866 XR_006393640.1 0 0 16 4 3 NA NA NA NA NA NA 38867 XM_029351834.2 465 442 386 105 819 P23508 7.35e-96 Colorectal mutant cancer protein (Protein MCC) Homo sapiens (Human) establishment of protein localization [GO:0045184]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of epithelial cell proliferation [GO:0050680]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055] GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0007165; GO:0010633; GO:0016055; GO:0030027; GO:0036464; GO:0038023; GO:0045184; GO:0050680; GO:0090090 38868 XM_044308521.1 132 125 86 70 118 P42942 8.32e-26 Uncharacterized GTP-binding protein YGR210C Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) NA GO:0005525; GO:0005737; GO:0016887 38869 XM_044308521.1 132 125 86 70 118 P42942 8.32e-26 Uncharacterized GTP-binding protein YGR210C Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) NA GO:0005525; GO:0005737; GO:0016887 38870 XM_044308521.1 132 125 86 70 118 P42942 8.32e-26 Uncharacterized GTP-binding protein YGR210C Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) NA GO:0005525; GO:0005737; GO:0016887 38871 XR_006392998.1 41 2 25 5 151 NA NA NA NA NA NA 38872 XM_029336226.2 169 26 110 225 346 O96006 1.21e-45 E3 SUMO-protein ligase ZBED1 (EC 2.3.2.-) (DNA replication-related element-binding factor) (Putative Ac-like transposable element) (Zinc finger BED domain-containing protein 1) (dREF homolog) Homo sapiens (Human) negative regulation by host of viral genome replication [GO:0044828]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein autosumoylation [GO:1990466]; protein sumoylation [GO:0016925]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000785; GO:0000978; GO:0000981; GO:0001228; GO:0003712; GO:0003713; GO:0005634; GO:0005654; GO:0005813; GO:0006355; GO:0006357; GO:0016605; GO:0016925; GO:0019789; GO:0031965; GO:0042802; GO:0043565; GO:0044828; GO:0045944; GO:0046872; GO:0046983; GO:0061665; GO:1990466; GO:1990837 38873 XM_029336787.2 81 46 89 348 205 G3M4F8 1.62e-34 Octopamine receptor beta-2R (CsOA2B2) Chilo suppressalis (Asiatic rice borer moth) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cellular response to amine stimulus [GO:0071418]; octopamine signaling pathway [GO:0071927]; tyramine signaling pathway [GO:0071928] GO:0004989; GO:0005886; GO:0007189; GO:0008226; GO:0016020; GO:0071418; GO:0071927; GO:0071928 38874 XR_006396277.1 6 43 4 4 9 NA NA NA NA NA NA 38875 XM_044321671.1 38 42 56 46 61 Q8K2J9 1.63e-110 BTB/POZ domain-containing protein 6 Mus musculus (Mouse) neurogenesis [GO:0022008] GO:0005829; GO:0022008 38876 XM_029324506.2 80 0 17 0 0 NA NA NA NA NA NA 38877 XM_044318310.1 10 3 0 0 0 NA NA NA NA NA NA 38878 XM_029334906.2 0 248 155 505 550 Q9UBE8 0 Serine/threonine-protein kinase NLK (EC 2.7.11.24) (Nemo-like kinase) (Protein LAK1) Homo sapiens (Human) intracellular signal transduction [GO:0035556]; negative regulation of Wnt signaling pathway [GO:0030178]; peptidyl-threonine phosphorylation [GO:0018107]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of DNA-templated transcription [GO:0006355]; serine phosphorylation of STAT protein [GO:0042501]; transforming growth factor beta receptor signaling pathway [GO:0007179]; Wnt signaling pathway, calcium modulating pathway [GO:0007223] GO:0000287; GO:0004672; GO:0004674; GO:0004707; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006355; GO:0006468; GO:0007179; GO:0007223; GO:0018107; GO:0030178; GO:0031625; GO:0035556; GO:0042169; GO:0042501; GO:0046777; GO:0050821; GO:0106310; GO:0140297 38879 XM_044308133.1 0 0 0 2 11 NA NA NA NA NA NA 38880 XM_029333844.2 16720 22228 14173 15093 14564 P40792 1.51e-106 Ras-related protein Rac1 Drosophila melanogaster (Fruit fly) actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; activation of protein kinase activity [GO:0032147]; axon extension [GO:0048675]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; axonal fasciculation [GO:0007413]; border follicle cell migration [GO:0007298]; cell competition in a multicellular organism [GO:0035212]; cell morphogenesis [GO:0000902]; cortical actin cytoskeleton organization [GO:0030866]; cortical cytoskeleton organization [GO:0030865]; dendrite development [GO:0016358]; determination of digestive tract left/right asymmetry [GO:0071907]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal closure, amnioserosa morphology change [GO:0046664]; dorsal closure, elongation of leading edge cells [GO:0007394]; dorsal closure, spreading of leading edge cells [GO:0007395]; embryonic anterior midgut (ectodermal) morphogenesis [GO:0048615]; encapsulation of foreign target [GO:0035010]; engulfment of apoptotic cell [GO:0043652]; establishment or maintenance of cell polarity [GO:0007163]; germ-band shortening [GO:0007390]; glial cell migration [GO:0008347]; head involution [GO:0008258]; hemocyte development [GO:0007516]; hemocyte migration [GO:0035099]; imaginal disc-derived wing hair site selection [GO:0035320]; immune response-regulating cell surface receptor signaling pathway involved in phagocytosis [GO:0002433]; JNK cascade [GO:0007254]; lamellipodium assembly [GO:0030032]; melanotic encapsulation of foreign target [GO:0035011]; memory [GO:0007613]; mesodermal cell migration [GO:0008078]; motor neuron axon guidance [GO:0008045]; muscle attachment [GO:0016203]; muscle cell development [GO:0055001]; myoblast fusion [GO:0007520]; myoblast proliferation [GO:0051450]; negative regulation of lamellipodium assembly [GO:0010593]; negative regulation of myotube cell migration [GO:0110125]; nephrocyte filtration [GO:0097206]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; open tracheal system development [GO:0007424]; peripheral nervous system development [GO:0007422]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669]; positive regulation of border follicle cell migration [GO:1903688]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of wound healing [GO:0090303]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of adherens junction organization [GO:1903391]; regulation of axonogenesis [GO:0050770]; regulation of cell shape [GO:0008360]; regulation of dendrite morphogenesis [GO:0048814]; regulation of locomotor rhythm [GO:1904059]; regulation of synapse assembly [GO:0051963]; regulation of synapse organization [GO:0050807]; response to wounding [GO:0009611]; rhabdomere development [GO:0042052]; salivary gland morphogenesis [GO:0007435]; sensory perception of touch [GO:0050975]; small GTPase mediated signal transduction [GO:0007264]; tracheal outgrowth, open tracheal system [GO:0007426]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; ventral cord development [GO:0007419] GO:0000902; GO:0001726; GO:0001954; GO:0002433; GO:0003924; GO:0005525; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0005938; GO:0007015; GO:0007163; GO:0007254; GO:0007264; GO:0007298; GO:0007390; GO:0007391; GO:0007394; GO:0007395; GO:0007411; GO:0007413; GO:0007419; GO:0007422; GO:0007424; GO:0007426; GO:0007435; GO:0007516; GO:0007520; GO:0007613; GO:0008045; GO:0008078; GO:0008258; GO:0008347; GO:0008360; GO:0009611; GO:0010593; GO:0016028; GO:0016199; GO:0016203; GO:0016358; GO:0019901; GO:0030032; GO:0030036; GO:0030865; GO:0030866; GO:0031175; GO:0031410; GO:0031532; GO:0032147; GO:0032794; GO:0032956; GO:0035010; GO:0035011; GO:0035099; GO:0035212; GO:0035320; GO:0042052; GO:0042995; GO:0043652; GO:0045773; GO:0046330; GO:0046664; GO:0046843; GO:0048010; GO:0048615; GO:0048675; GO:0048812; GO:0048814; GO:0050770; GO:0050807; GO:0050975; GO:0051017; GO:0051450; GO:0051491; GO:0051963; GO:0055001; GO:0071902; GO:0071907; GO:0090303; GO:0097206; GO:0110125; GO:1902669; GO:1903391; GO:1903688; GO:1904059 38881 XM_044328211.1 1852 740 1648 1418 1395 Q8BJ51 1.32e-127 UNC93-like protein MFSD11 (Major facilitator superfamily domain-containing protein 11) (Protein ET) Mus musculus (Mouse) NA GO:0016020 38882 XM_044313089.1 222 0 0 0 0 NA NA NA NA NA NA 38883 XM_029351489.2 86 0 0 142 0 Q5TZA2 7e-67 Rootletin (Ciliary rootlet coiled-coil protein) Homo sapiens (Human) cellular homeostasis [GO:0019725]; centriole-centriole cohesion [GO:0010457]; centrosome cycle [GO:0007098]; ciliary basal body organization [GO:0032053]; epithelial structure maintenance [GO:0010669]; establishment of localization in cell [GO:0051649]; establishment of organelle localization [GO:0051656]; photoreceptor cell maintenance [GO:0045494]; positive regulation of cilium assembly [GO:0045724]; positive regulation of protein localization to cilium [GO:1903566]; protein localization [GO:0008104]; protein localization to organelle [GO:0033365] GO:0001917; GO:0003779; GO:0005198; GO:0005200; GO:0005813; GO:0005814; GO:0005829; GO:0005886; GO:0007098; GO:0008104; GO:0010457; GO:0010669; GO:0015629; GO:0019725; GO:0019894; GO:0032053; GO:0033365; GO:0035253; GO:0045494; GO:0045724; GO:0051649; GO:0051656; GO:0070062; GO:0097729; GO:0120219; GO:1903566 38884 XM_029336735.2 0 0 0 0 244 Q9UKP5 0 A disintegrin and metalloproteinase with thrombospondin motifs 6 (ADAM-TS 6) (ADAM-TS6) (ADAMTS-6) (EC 3.4.24.-) Homo sapiens (Human) aorta development [GO:0035904]; cardiac septum development [GO:0003279]; coronary vasculature development [GO:0060976]; extracellular matrix organization [GO:0030198]; kidney development [GO:0001822]; proteolysis [GO:0006508] GO:0001822; GO:0003279; GO:0004222; GO:0005576; GO:0006508; GO:0008237; GO:0030198; GO:0031012; GO:0035904; GO:0046872; GO:0060976 38885 XM_029334788.2 405 355 220 334 444 Q9NUJ3 7.09e-97 T-complex protein 11-like protein 1 Homo sapiens (Human) signal transduction [GO:0007165] GO:0005874; GO:0007165 38886 XM_044329063.1 172 171 243 190 77 NA NA NA NA NA NA 38887 XM_029356310.2 271 454 257 406 256 NA NA NA NA NA NA 38888 XM_029328564.2 645 248 462 494 957 Q8IUC4 1.21e-112 Rhophilin-2 (76 kDa RhoB effector protein) (GTP-Rho-binding protein 2) (p76RBE) Homo sapiens (Human) glomerular filtration [GO:0003094]; negative regulation of stress fiber assembly [GO:0051497]; signal transduction [GO:0007165] GO:0003094; GO:0005829; GO:0005886; GO:0007165; GO:0048471; GO:0051497 38889 XR_006395876.1 253 233 195 266 240 NA NA NA NA NA NA 38890 XM_044314166.1 204 5 72 112 49 NA NA NA NA NA NA 38891 XM_029347354.2 10 0 3 1 25 NA NA NA NA NA NA 38892 XM_044311795.1 6 11 22 26 69 NA NA NA NA NA NA 38893 XM_044329284.1 8 0 0 0 0 Q28FH2 0 N-terminal kinase-like protein (SCY1-like protein 1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) protein phosphorylation [GO:0006468] GO:0004672; GO:0005524; GO:0006468 38894 XM_044314819.1 99 98 84 161 131 NA NA NA NA NA NA 38895 XR_006395329.1 91 121 189 238 103 NA NA NA NA NA NA 38896 XM_044325804.1 1943 1006 1687 1329 1702 NA NA NA NA NA NA 38897 XM_029340600.2 222 24 8 39 195 NA NA NA NA NA NA 38898 XM_029329941.2 132 175 220 153 265 Q9NSA2 5.97e-38 Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) Homo sapiens (Human) potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005250; GO:0005886; GO:0008076; GO:0014069; GO:0016020; GO:0034765; GO:0043025; GO:0043197; GO:0045211; GO:0046872; GO:0051260; GO:0071805 38899 XM_029351077.2 1593 909 723 920 997 NA NA NA NA NA NA 38900 XM_044309074.1 517 34 14 58 45 NA NA NA NA NA NA 38901 XM_044310515.1 285 485 387 622 287 Q7RTR2 1.58e-73 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 38902 XM_044310515.1 285 485 387 622 287 Q7RTR2 9.69e-72 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 38903 XM_044310515.1 285 485 387 622 287 Q7RTR2 4.55e-71 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 38904 XM_044310515.1 285 485 387 622 287 Q7RTR2 2.61e-63 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 38905 XM_044310515.1 285 485 387 622 287 Q7RTR2 1.44e-41 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 38906 XM_044310515.1 285 485 387 622 287 Q7RTR2 2.23e-41 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 38907 XM_044310515.1 285 485 387 622 287 Q7RTR2 2.35e-39 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 38908 XM_044310515.1 285 485 387 622 287 Q7RTR2 5.26e-39 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 38909 XM_044310515.1 285 485 387 622 287 Q7RTR2 5.32e-36 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 38910 XM_044310515.1 285 485 387 622 287 Q7RTR2 3.98e-35 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 38911 XM_044310515.1 285 485 387 622 287 Q7RTR2 8.62e-34 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 38912 XM_044310515.1 285 485 387 622 287 Q7RTR2 5.47e-24 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 38913 XM_044310321.1 41 23 46 49 59 NA NA NA NA NA NA 38914 XM_029355590.2 811 1223 887 283 847 NA NA NA NA NA NA 38915 XM_044328945.1 441 683 359 592 270 P16273 4.55e-36 Pathogen-related protein Hordeum vulgare (Barley) defense response [GO:0006952]; response to biotic stimulus [GO:0009607] GO:0006952; GO:0009607 38916 XM_029344082.2 712 599 346 585 492 Q8JHF2 3.94e-92 Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase) Danio rerio (Zebrafish) (Brachydanio rerio) cell differentiation [GO:0030154]; fin regeneration [GO:0031101]; hypochord development [GO:0055016]; negative regulation of neuron differentiation [GO:0045665]; nervous system development [GO:0007399]; Notch signaling pathway [GO:0007219]; pattern specification process [GO:0007389]; regulation of Notch signaling pathway [GO:0008593] GO:0000139; GO:0007219; GO:0007389; GO:0007399; GO:0008375; GO:0008593; GO:0030154; GO:0031101; GO:0033829; GO:0045665; GO:0046872; GO:0055016 38917 XM_029332405.2 767 642 563 706 359 NA NA NA NA NA NA 38918 XR_006395142.1 521 867 212 880 1259 NA NA NA NA NA NA 38919 XR_003824598.1 28 13 11 31 40 NA NA NA NA NA NA 38920 XR_003822924.2 3011 4934 1283 2390 1772 Q6P026 3.94e-46 Barrier-to-autointegration factor Danio rerio (Zebrafish) (Brachydanio rerio) chromatin organization [GO:0006325]; chromosome condensation [GO:0030261]; chromosome segregation [GO:0007059]; mitotic nuclear membrane reassembly [GO:0007084]; negative regulation of protein ADP-ribosylation [GO:0010836]; negative regulation of type I interferon production [GO:0032480]; response to oxidative stress [GO:0006979] GO:0000785; GO:0003677; GO:0005635; GO:0005654; GO:0005737; GO:0006325; GO:0006979; GO:0007059; GO:0007084; GO:0010836; GO:0030261; GO:0032480 38921 XM_044316519.1 0 0 0 0 38 P81139 2.17e-71 Pancreatic lipase-related protein 2 (PL-RP2) (Cytotoxic T lymphocyte lipase) (GPL) (Galactolipase) (EC 3.1.1.26) (Triacylglycerol lipase) (EC 3.1.1.3) Cavia porcellus (Guinea pig) galactolipid catabolic process [GO:0019376]; lipid metabolic process [GO:0006629]; phospholipid catabolic process [GO:0009395]; phospholipid metabolic process [GO:0006644]; triglyceride catabolic process [GO:0019433] GO:0004620; GO:0004806; GO:0005509; GO:0005615; GO:0006629; GO:0006644; GO:0009395; GO:0016020; GO:0019376; GO:0019433; GO:0031410; GO:0043005; GO:0047372; GO:0047714; GO:0102549 38922 XM_029343704.2 33 0 24 26 37 NA NA NA NA NA NA 38923 XM_044314018.1 6 2 1 0 6 NA NA NA NA NA NA 38924 XR_003826141.2 59 99 48 70 37 NA NA NA NA NA NA 38925 XM_029344205.2 19 22 6 7 2 NA NA NA NA NA NA 38926 XM_029345559.2 750 391 361 516 738 Q7YR39 0 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.4.13) (ATP-dependent RNA helicase #3) (DEAH-box protein 16) Pan troglodytes (Chimpanzee) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005654; GO:0016887; GO:0071005 38927 XM_029345040.2 425 205 0 342 560 NA NA NA NA NA NA 38928 XR_006391553.1 70 180 27 85 166 NA NA NA NA NA NA 38929 XM_044326425.1 292 379 185 330 613 NA NA NA NA NA NA 38930 XM_029333314.2 330 90 104 124 145 Q68F72 2.67e-88 Solute carrier family 15 member 4 Xenopus laevis (African clawed frog) dipeptide import across plasma membrane [GO:0140206]; innate immune response [GO:0045087]; mast cell homeostasis [GO:0033023]; peptidoglycan transport [GO:0015835]; positive regulation of innate immune response [GO:0045089]; positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [GO:0070430]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of toll-like receptor 7 signaling pathway [GO:0034157]; positive regulation of toll-like receptor 8 signaling pathway [GO:0034161]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; protein transport [GO:0015031]; regulation of isotype switching to IgG isotypes [GO:0048302]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424] GO:0005290; GO:0005765; GO:0015031; GO:0015333; GO:0015647; GO:0015835; GO:0031901; GO:0033023; GO:0034157; GO:0034161; GO:0034165; GO:0036020; GO:0045087; GO:0045089; GO:0048302; GO:0070424; GO:0070430; GO:0070434; GO:0071916; GO:0140206 38931 XM_044308817.1 0 0 0 0 8 NA NA NA NA NA NA 38932 XM_044324793.1 283 416 223 351 205 P07949 2.48e-77 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; axon guidance [GO:0007411]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; lymphocyte migration into lymphoid organs [GO:0097021]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; posterior midgut development [GO:0007497]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006468; GO:0006919; GO:0007156; GO:0007158; GO:0007165; GO:0007169; GO:0007411; GO:0007497; GO:0009410; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0038023; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0097021; GO:0098797; GO:2001241 38933 XR_006395800.1 46 35 24 12 44 Q80VL3 1.7e-63 Prickle planar cell polarity protein 3 (LIM domain only protein 6) (LMO-6) (Prickle-like protein 3) (Pk3) (Triple LIM domain protein 6) Mus musculus (Mouse) cell projection organization [GO:0030030] GO:0005739; GO:0005886; GO:0008270; GO:0030030 38934 XM_044319261.1 0 0 234 0 0 Q86W24 6.05e-38 NACHT, LRR and PYD domains-containing protein 14 (Nucleotide-binding oligomerization domain protein 5) Homo sapiens (Human) cell differentiation [GO:0030154]; regulation of inflammatory response [GO:0050727]; spermatogenesis [GO:0007283] GO:0005524; GO:0005737; GO:0007283; GO:0030154; GO:0050727 38935 XM_044311283.1 29 0 0 12 3 NA NA NA NA NA NA 38936 XM_044312070.1 7 28 2 1 1 NA NA NA NA NA NA 38937 XM_044325444.1 741 802 668 589 861 Q9JKP8 9.93e-24 Chromatin accessibility complex protein 1 (CHRAC-1) (DNA polymerase epsilon subunit p15) (NF-YC-like protein) (YC-like protein 1) (YCL1) Mus musculus (Mouse) chromatin remodeling [GO:0006338]; nucleosome assembly [GO:0006334]; regulation of DNA replication [GO:0006275] GO:0003677; GO:0003887; GO:0005634; GO:0005721; GO:0006275; GO:0006334; GO:0006338; GO:0008623; GO:0046982 38938 XM_044311675.1 9 29 37 44 8 Q8R4B8 2.84e-29 NACHT, LRR and PYD domains-containing protein 3 (EC 3.6.4.-) (Cold autoinflammatory syndrome 1 protein homolog) (Cryopyrin) (Mast cell maturation-associated-inducible protein 1) (PYRIN-containing APAF1-like protein 1) Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptidoglycan [GO:0071224]; cellular response to virus [GO:0098586]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of biotic stimulus [GO:0009595]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; NLRP3 inflammasome complex assembly [GO:0044546]; osmosensory signaling pathway [GO:0007231]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-13 production [GO:0032736]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-5 production [GO:0032754]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T-helper 17 cell differentiation [GO:2000321]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type 2 immune response [GO:0002830]; protein homooligomerization [GO:0051260]; pyroptosis [GO:0070269]; regulation of inflammatory response [GO:0050727]; response to ethanol [GO:0045471]; response to organic cyclic compound [GO:0014070] GO:0000139; GO:0002221; GO:0002523; GO:0002526; GO:0002674; GO:0002720; GO:0002830; GO:0005524; GO:0005576; GO:0005634; GO:0005737; GO:0005739; GO:0005783; GO:0005815; GO:0005829; GO:0006919; GO:0006954; GO:0007231; GO:0009595; GO:0014070; GO:0016020; GO:0016887; GO:0031021; GO:0032088; GO:0032691; GO:0032731; GO:0032736; GO:0032753; GO:0032754; GO:0035591; GO:0042802; GO:0043280; GO:0043531; GO:0043565; GO:0044546; GO:0045087; GO:0045471; GO:0045630; GO:0045944; GO:0050727; GO:0050728; GO:0050729; GO:0050830; GO:0051092; GO:0051260; GO:0051607; GO:0061702; GO:0070269; GO:0070273; GO:0071222; GO:0071224; GO:0072559; GO:0098586; GO:0140297; GO:0140299; GO:1901223; GO:1901981; GO:2000321; GO:2000553 38939 XM_029343594.2 8 8 0 19 48 Q6UXI7 5.61e-30 Vitrin Homo sapiens (Human) extracellular matrix organization [GO:0030198]; positive regulation of cell-substrate adhesion [GO:0010811]; spinal cord development [GO:0021510] GO:0005539; GO:0005576; GO:0005614; GO:0010811; GO:0021510; GO:0030198; GO:0062023 38940 XM_029351462.2 81 69 19 0 34 NA NA NA NA NA NA 38941 XR_006396873.1 6 0 0 0 11 NA NA NA NA NA NA 38942 XR_003824266.2 40890 9583 11947 27951 22460 NA NA NA NA NA NA 38943 XM_044323819.1 948 254 393 429 656 Q15434 4.96e-77 RNA-binding motif, single-stranded-interacting protein 2 (Suppressor of CDC2 with RNA-binding motif 3) Homo sapiens (Human) RNA processing [GO:0006396] GO:0003723; GO:0003730; GO:0005634; GO:0005829; GO:0006396; GO:0008143; GO:0008266; GO:1990904 38944 XM_044325224.1 62 76 22 138 152 NA NA NA NA NA NA 38945 XM_029333239.2 1053 1943 911 1357 708 NA NA NA NA NA NA 38946 XM_044323783.1 17 9 0 5 0 NA NA NA NA NA NA 38947 XM_044327951.1 740 873 376 717 598 P60881 9.51e-68 Synaptosomal-associated protein 25 (SNAP-25) (Super protein) (SUP) (Synaptosomal-associated 25 kDa protein) Rattus norvegicus (Rat) associative learning [GO:0008306]; axonogenesis [GO:0007409]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; endosomal transport [GO:0016197]; exocytic insertion of neurotransmitter receptor to postsynaptic membrane [GO:0098967]; exocytosis [GO:0006887]; growth hormone secretion [GO:0030252]; localization [GO:0051179]; locomotory behavior [GO:0007626]; long-term memory [GO:0007616]; long-term synaptic potentiation [GO:0060291]; neuron differentiation [GO:0030182]; neurotransmitter receptor internalization [GO:0099590]; neurotransmitter secretion [GO:0007269]; positive regulation of hormone secretion [GO:0046887]; positive regulation of insulin secretion [GO:0032024]; presynaptic dense core vesicle exocytosis [GO:0099525]; regulation of establishment of protein localization [GO:0070201]; regulation of neuron projection development [GO:0010975]; regulation of synapse assembly [GO:0051963]; sleep [GO:0030431]; SNARE complex assembly [GO:0035493]; synaptic vesicle exocytosis [GO:0016079]; synaptic vesicle fusion to presynaptic active zone membrane [GO:0031629]; synaptic vesicle priming [GO:0016082]; vesicle fusion [GO:0006906] GO:0000149; GO:0001917; GO:0005249; GO:0005484; GO:0005737; GO:0005768; GO:0005802; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006906; GO:0007269; GO:0007409; GO:0007616; GO:0007626; GO:0008021; GO:0008076; GO:0008289; GO:0008306; GO:0010975; GO:0015629; GO:0016020; GO:0016079; GO:0016082; GO:0016197; GO:0017022; GO:0017075; GO:0019904; GO:0019905; GO:0030027; GO:0030175; GO:0030182; GO:0030252; GO:0030424; GO:0030426; GO:0030431; GO:0031201; GO:0031234; GO:0031629; GO:0032024; GO:0035493; GO:0036477; GO:0042734; GO:0043005; GO:0043025; GO:0043195; GO:0043229; GO:0044295; GO:0044325; GO:0045121; GO:0045202; GO:0046887; GO:0047485; GO:0048306; GO:0048471; GO:0048787; GO:0048791; GO:0051179; GO:0051963; GO:0060090; GO:0060291; GO:0070032; GO:0070033; GO:0070044; GO:0070201; GO:0097470; GO:0098793; GO:0098794; GO:0098888; GO:0098967; GO:0098978; GO:0099525; GO:0099590 38948 XM_044310034.1 0 44 0 0 27 P70490 4.37e-52 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 38949 XM_044310034.1 0 44 0 0 27 P70490 4.99e-52 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 38950 XM_044310034.1 0 44 0 0 27 P70490 3.78e-51 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 38951 XM_044310034.1 0 44 0 0 27 P70490 3.85e-51 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 38952 XM_044310034.1 0 44 0 0 27 P70490 1.19e-50 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 38953 XM_044310034.1 0 44 0 0 27 P70490 2.99e-50 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 38954 XM_044310034.1 0 44 0 0 27 P70490 3.39e-50 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 38955 XM_044310034.1 0 44 0 0 27 P70490 6.83e-50 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 38956 XM_044310034.1 0 44 0 0 27 P70490 1.06e-49 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 38957 XM_044310034.1 0 44 0 0 27 P70490 2.04e-49 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 38958 XM_044310034.1 0 44 0 0 27 P70490 3.15e-49 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 38959 XM_044310034.1 0 44 0 0 27 P70490 3.43e-49 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 38960 XM_044310034.1 0 44 0 0 27 P70490 7.54e-49 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 38961 XM_044310034.1 0 44 0 0 27 P70490 8.69e-49 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 38962 XM_044310034.1 0 44 0 0 27 P70490 1.45e-48 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 38963 XM_044310034.1 0 44 0 0 27 P70490 3.89e-48 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 38964 XM_044310034.1 0 44 0 0 27 P70490 1.23e-46 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 38965 XM_029342834.2 49 36 36 118 31 P41777 6.71e-29 Nucleolar and coiled-body phosphoprotein 1 (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar 130 kDa protein) (Nucleolar phosphoprotein p130) Rattus norvegicus (Rat) axonogenesis [GO:0007409]; box H/ACA RNA metabolic process [GO:0033979]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; nucleolus organization [GO:0007000]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of protein import into nucleus [GO:0042306]; regulation of synaptic plasticity [GO:0048167]; regulation of translation [GO:0006417]; response to osmotic stress [GO:0006970] GO:0001093; GO:0001650; GO:0005524; GO:0005525; GO:0005654; GO:0005730; GO:0005737; GO:0006417; GO:0006970; GO:0007000; GO:0007409; GO:0008139; GO:0008284; GO:0014029; GO:0014032; GO:0015030; GO:0019904; GO:0030674; GO:0031428; GO:0031429; GO:0033979; GO:0034512; GO:0034513; GO:0042306; GO:0045893; GO:0046982; GO:0048167; GO:0062064; GO:0062065; GO:0140678 38966 XM_044313165.1 55 0 32 0 0 NA NA NA NA NA NA 38967 XR_006397111.1 26 0 58 8 551 NA NA NA NA NA NA 38968 XM_044314052.1 0 28 12 0 73 Q6P0D1 5.8e-76 Zinc transporter 6 (ZnT-6) (Solute carrier family 30 member 6) Danio rerio (Zebrafish) (Brachydanio rerio) zinc ion import into Golgi lumen [GO:1904257]; zinc ion transport [GO:0006829] GO:0005385; GO:0005794; GO:0006829; GO:0032588; GO:1904257 38969 XM_029348557.2 162 0 268 171 209 Q9Z139 1.15e-123 Inactive tyrosine-protein kinase transmembrane receptor ROR1 (mROR1) (Neurotrophic tyrosine kinase, receptor-related 1) Mus musculus (Mouse) astrocyte development [GO:0014002]; inner ear development [GO:0048839]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of kinase activity [GO:0033674]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; sensory perception of sound [GO:0007605] GO:0001725; GO:0004714; GO:0005524; GO:0005737; GO:0005886; GO:0007605; GO:0009986; GO:0010976; GO:0014002; GO:0014068; GO:0017147; GO:0033674; GO:0042813; GO:0043123; GO:0043235; GO:0043679; GO:0048839; GO:0051092 38970 XM_029356176.2 58 21 9 93 27 Q7ZWG6 2.66e-53 Proton-coupled folate transporter (Solute carrier family 46 member 1) Danio rerio (Zebrafish) (Brachydanio rerio) transmembrane transport [GO:0055085] GO:0005542; GO:0005768; GO:0005886; GO:0010008; GO:0015293; GO:0015350; GO:0016020; GO:0016323; GO:0016324; GO:0022857; GO:0055085 38971 XM_029331621.2 0 157 336 269 742 Q9NR09 3.37e-176 Baculoviral IAP repeat-containing protein 6 (EC 2.3.2.27) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (RING-type E3 ubiquitin transferase BIRC6) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON) Homo sapiens (Human) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell population proliferation [GO:0008283]; labyrinthine layer development [GO:0060711]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of peptidase activity [GO:0010466]; positive regulation of cell population proliferation [GO:0008284]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell population proliferation [GO:0042127]; regulation of cytokinesis [GO:0032465]; regulation of endopeptidase activity [GO:0052548]; spongiotrophoblast layer development [GO:0060712] GO:0000922; GO:0004842; GO:0004869; GO:0005634; GO:0005768; GO:0005802; GO:0005815; GO:0005829; GO:0006468; GO:0006915; GO:0007049; GO:0008283; GO:0008284; GO:0010466; GO:0016020; GO:0016567; GO:0030496; GO:0032465; GO:0042127; GO:0043066; GO:0051301; GO:0052548; GO:0060711; GO:0060712; GO:0061631; GO:0090543; GO:2001237 38972 XM_029331621.2 0 157 336 269 742 Q9NR09 3.91e-91 Baculoviral IAP repeat-containing protein 6 (EC 2.3.2.27) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (RING-type E3 ubiquitin transferase BIRC6) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON) Homo sapiens (Human) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell population proliferation [GO:0008283]; labyrinthine layer development [GO:0060711]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of peptidase activity [GO:0010466]; positive regulation of cell population proliferation [GO:0008284]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell population proliferation [GO:0042127]; regulation of cytokinesis [GO:0032465]; regulation of endopeptidase activity [GO:0052548]; spongiotrophoblast layer development [GO:0060712] GO:0000922; GO:0004842; GO:0004869; GO:0005634; GO:0005768; GO:0005802; GO:0005815; GO:0005829; GO:0006468; GO:0006915; GO:0007049; GO:0008283; GO:0008284; GO:0010466; GO:0016020; GO:0016567; GO:0030496; GO:0032465; GO:0042127; GO:0043066; GO:0051301; GO:0052548; GO:0060711; GO:0060712; GO:0061631; GO:0090543; GO:2001237 38973 XM_029331621.2 0 157 336 269 742 Q9NR09 5.54e-73 Baculoviral IAP repeat-containing protein 6 (EC 2.3.2.27) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (RING-type E3 ubiquitin transferase BIRC6) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON) Homo sapiens (Human) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell population proliferation [GO:0008283]; labyrinthine layer development [GO:0060711]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of peptidase activity [GO:0010466]; positive regulation of cell population proliferation [GO:0008284]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell population proliferation [GO:0042127]; regulation of cytokinesis [GO:0032465]; regulation of endopeptidase activity [GO:0052548]; spongiotrophoblast layer development [GO:0060712] GO:0000922; GO:0004842; GO:0004869; GO:0005634; GO:0005768; GO:0005802; GO:0005815; GO:0005829; GO:0006468; GO:0006915; GO:0007049; GO:0008283; GO:0008284; GO:0010466; GO:0016020; GO:0016567; GO:0030496; GO:0032465; GO:0042127; GO:0043066; GO:0051301; GO:0052548; GO:0060711; GO:0060712; GO:0061631; GO:0090543; GO:2001237 38974 XM_029331621.2 0 157 336 269 742 Q9NR09 1.16e-56 Baculoviral IAP repeat-containing protein 6 (EC 2.3.2.27) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (RING-type E3 ubiquitin transferase BIRC6) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON) Homo sapiens (Human) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell population proliferation [GO:0008283]; labyrinthine layer development [GO:0060711]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of peptidase activity [GO:0010466]; positive regulation of cell population proliferation [GO:0008284]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell population proliferation [GO:0042127]; regulation of cytokinesis [GO:0032465]; regulation of endopeptidase activity [GO:0052548]; spongiotrophoblast layer development [GO:0060712] GO:0000922; GO:0004842; GO:0004869; GO:0005634; GO:0005768; GO:0005802; GO:0005815; GO:0005829; GO:0006468; GO:0006915; GO:0007049; GO:0008283; GO:0008284; GO:0010466; GO:0016020; GO:0016567; GO:0030496; GO:0032465; GO:0042127; GO:0043066; GO:0051301; GO:0052548; GO:0060711; GO:0060712; GO:0061631; GO:0090543; GO:2001237 38975 XM_029331621.2 0 157 336 269 742 Q9NR09 2.28e-33 Baculoviral IAP repeat-containing protein 6 (EC 2.3.2.27) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (RING-type E3 ubiquitin transferase BIRC6) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON) Homo sapiens (Human) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell population proliferation [GO:0008283]; labyrinthine layer development [GO:0060711]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of peptidase activity [GO:0010466]; positive regulation of cell population proliferation [GO:0008284]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell population proliferation [GO:0042127]; regulation of cytokinesis [GO:0032465]; regulation of endopeptidase activity [GO:0052548]; spongiotrophoblast layer development [GO:0060712] GO:0000922; GO:0004842; GO:0004869; GO:0005634; GO:0005768; GO:0005802; GO:0005815; GO:0005829; GO:0006468; GO:0006915; GO:0007049; GO:0008283; GO:0008284; GO:0010466; GO:0016020; GO:0016567; GO:0030496; GO:0032465; GO:0042127; GO:0043066; GO:0051301; GO:0052548; GO:0060711; GO:0060712; GO:0061631; GO:0090543; GO:2001237 38976 XM_029331621.2 0 157 336 269 742 Q9NR09 6.02e-32 Baculoviral IAP repeat-containing protein 6 (EC 2.3.2.27) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (RING-type E3 ubiquitin transferase BIRC6) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON) Homo sapiens (Human) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell population proliferation [GO:0008283]; labyrinthine layer development [GO:0060711]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of peptidase activity [GO:0010466]; positive regulation of cell population proliferation [GO:0008284]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell population proliferation [GO:0042127]; regulation of cytokinesis [GO:0032465]; regulation of endopeptidase activity [GO:0052548]; spongiotrophoblast layer development [GO:0060712] GO:0000922; GO:0004842; GO:0004869; GO:0005634; GO:0005768; GO:0005802; GO:0005815; GO:0005829; GO:0006468; GO:0006915; GO:0007049; GO:0008283; GO:0008284; GO:0010466; GO:0016020; GO:0016567; GO:0030496; GO:0032465; GO:0042127; GO:0043066; GO:0051301; GO:0052548; GO:0060711; GO:0060712; GO:0061631; GO:0090543; GO:2001237 38977 XM_029350623.2 377 515 256 467 405 Q147U1 7.18e-55 Zinc finger protein 846 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000977; GO:0000981; GO:0001227; GO:0005634; GO:0006357; GO:0046872 38978 XM_029350623.2 377 515 256 467 405 Q147U1 1.48e-53 Zinc finger protein 846 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000977; GO:0000981; GO:0001227; GO:0005634; GO:0006357; GO:0046872 38979 XM_029350623.2 377 515 256 467 405 Q147U1 5.09e-52 Zinc finger protein 846 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000977; GO:0000981; GO:0001227; GO:0005634; GO:0006357; GO:0046872 38980 XM_029350623.2 377 515 256 467 405 Q147U1 1.4e-50 Zinc finger protein 846 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000977; GO:0000981; GO:0001227; GO:0005634; GO:0006357; GO:0046872 38981 XM_029350623.2 377 515 256 467 405 Q147U1 5.58e-50 Zinc finger protein 846 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000977; GO:0000981; GO:0001227; GO:0005634; GO:0006357; GO:0046872 38982 XM_029350623.2 377 515 256 467 405 Q147U1 8.84e-48 Zinc finger protein 846 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000977; GO:0000981; GO:0001227; GO:0005634; GO:0006357; GO:0046872 38983 XM_029350623.2 377 515 256 467 405 Q147U1 7.49e-35 Zinc finger protein 846 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000977; GO:0000981; GO:0001227; GO:0005634; GO:0006357; GO:0046872 38984 XM_029350283.2 0 0 0 0 34 Q6L8F3 3.14e-32 NA NA NA NA 38985 XM_044323558.1 323 40 192 73 748 NA NA NA NA NA NA 38986 XM_029353108.2 1011 511 502 669 509 Q6ZNA5 5.84e-44 Ferric-chelate reductase 1 (EC 1.-.-.-) (Stromal cell-derived receptor 2) (SDR-2) Homo sapiens (Human) cellular iron ion homeostasis [GO:0006879] GO:0006879; GO:0016020; GO:0016722; GO:0046872 38987 XM_029325388.2 5173 3810 2798 5286 3099 NA NA NA NA NA NA 38988 XM_044318342.1 179 127 86 150 173 A3KN83 0 Protein strawberry notch homolog 1 (Monocyte protein 3) (MOP-3) Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355]; regulation of response to stimulus [GO:0048583] GO:0005634; GO:0006355; GO:0031490; GO:0042393; GO:0048583 38989 XM_029332513.2 1394 1252 562 1618 1365 P07742 0 Ribonucleoside-diphosphate reductase large subunit (EC 1.17.4.1) (Ribonucleoside-diphosphate reductase subunit M1) (Ribonucleotide reductase large subunit) Mus musculus (Mouse) 2'-deoxyribonucleotide biosynthetic process [GO:0009265]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA repair [GO:0006281]; DNA synthesis involved in DNA repair [GO:0000731]; mitochondrial DNA replication [GO:0006264]; positive regulation of G0 to G1 transition [GO:0070318]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; protein heterotetramerization [GO:0051290]; ribonucleoside diphosphate metabolic process [GO:0009185] GO:0000731; GO:0004748; GO:0005524; GO:0005635; GO:0005737; GO:0005739; GO:0005829; GO:0005971; GO:0006264; GO:0006281; GO:0009185; GO:0009263; GO:0009265; GO:0010971; GO:0017076; GO:0042802; GO:0042995; GO:0043025; GO:0051290; GO:0061731; GO:0070318; GO:0097718; GO:1900087 38990 XM_044327922.1 32 5 7 14 41 NA NA NA NA NA NA 38991 XM_044325313.1 0 1 7 3 4 NA NA NA NA NA NA 38992 XM_044317048.1 120 211 106 144 137 Q32L63 1.99e-84 Vacuolar protein sorting-associated protein VTA1 homolog Bos taurus (Bovine) late endosome to vacuole transport via multivesicular body sorting pathway [GO:0032511]; protein transport [GO:0015031] GO:0010008; GO:0015031; GO:0032511 38993 XM_044315237.1 97 34 0 45 23 NA NA NA NA NA NA 38994 XM_044308283.1 49 51 2 6 33 P49582 1.14e-85 Neuronal acetylcholine receptor subunit alpha-7 Mus musculus (Mouse) acetylcholine receptor signaling pathway [GO:0095500]; associative learning [GO:0008306]; B cell activation [GO:0042113]; behavioral response to ethanol [GO:0048149]; behavioral response to nicotine [GO:0035095]; calcium ion transport [GO:0006816]; chemical synaptic transmission [GO:0007268]; dendrite arborization [GO:0140059]; dendritic spine organization [GO:0097061]; endocytosis [GO:0006897]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; generation of ovulation cycle rhythm [GO:0060112]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; learning or memory [GO:0007611]; membrane depolarization [GO:0051899]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; modulation of excitatory postsynaptic potential [GO:0098815]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of tumor necrosis factor production [GO:0032720]; nervous system process [GO:0050877]; neuronal action potential [GO:0019228]; ovulation cycle [GO:0042698]; positive regulation of acetylcholine biosynthetic process [GO:1905923]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of CoA-transferase activity [GO:1905920]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure [GO:0001988]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of amyloid fibril formation [GO:1905906]; regulation of inflammatory response [GO:0050727]; regulation of membrane potential [GO:0042391]; regulation of neuron death [GO:1901214]; regulation of nitric oxide metabolic process [GO:0080164]; regulation of norepinephrine secretion [GO:0014061]; regulation of response to drug [GO:2001023]; regulation of synapse structural plasticity [GO:0051823]; regulation of synaptic transmission, cholinergic [GO:0032222]; regulation of synaptic transmission, dopaminergic [GO:0032225]; response to acetylcholine [GO:1905144]; response to amyloid-beta [GO:1904645]; response to cold [GO:0009409]; response to ethanol [GO:0045471]; response to food [GO:0032094]; response to nicotine [GO:0035094]; sensory processing [GO:0050893]; signal transduction [GO:0007165]; synapse organization [GO:0050808]; synaptic transmission, cholinergic [GO:0007271]; T cell activation [GO:0042110] GO:0001540; GO:0001933; GO:0001934; GO:0001988; GO:0005216; GO:0005231; GO:0005737; GO:0005886; GO:0005892; GO:0006811; GO:0006816; GO:0006897; GO:0007165; GO:0007268; GO:0007271; GO:0007611; GO:0007613; GO:0008179; GO:0008306; GO:0009409; GO:0009897; GO:0010628; GO:0014061; GO:0014069; GO:0015464; GO:0015643; GO:0016020; GO:0016324; GO:0017081; GO:0019228; GO:0019901; GO:0022848; GO:0030317; GO:0030424; GO:0030425; GO:0030426; GO:0030594; GO:0030673; GO:0032094; GO:0032222; GO:0032225; GO:0032279; GO:0032691; GO:0032715; GO:0032720; GO:0033138; GO:0034220; GO:0035094; GO:0035095; GO:0042110; GO:0042113; GO:0042166; GO:0042391; GO:0042698; GO:0042734; GO:0042803; GO:0043005; GO:0043025; GO:0043197; GO:0043198; GO:0044853; GO:0045121; GO:0045202; GO:0045211; GO:0045471; GO:0048149; GO:0050727; GO:0050728; GO:0050804; GO:0050808; GO:0050877; GO:0050893; GO:0051117; GO:0051247; GO:0051649; GO:0051823; GO:0051899; GO:0060112; GO:0070373; GO:0070374; GO:0080164; GO:0095500; GO:0097061; GO:0097110; GO:0098690; GO:0098793; GO:0098815; GO:0098897; GO:0098981; GO:0099171; GO:0099634; GO:0140059; GO:1900273; GO:1901214; GO:1902004; GO:1904315; GO:1904645; GO:1905144; GO:1905906; GO:1905920; GO:1905923; GO:2000463; GO:2001023 38995 XM_029355834.2 506 422 258 575 432 Q8TAM2 0 Tetratricopeptide repeat protein 8 (TPR repeat protein 8) (Bardet-Biedl syndrome 8 protein) Homo sapiens (Human) axon guidance [GO:0007411]; camera-type eye photoreceptor cell differentiation [GO:0060219]; cilium assembly [GO:0060271]; establishment of anatomical structure orientation [GO:0048560]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of planar polarity [GO:0001736]; fat cell differentiation [GO:0045444]; inner ear receptor cell stereocilium organization [GO:0060122]; multi-ciliated epithelial cell differentiation [GO:1903251]; multicellular organism growth [GO:0035264]; negative regulation of GTPase activity [GO:0034260]; non-motile cilium assembly [GO:1905515]; olfactory bulb development [GO:0021772]; protein localization to plasma membrane [GO:0072659]; protein transport [GO:0015031]; regulation of protein localization [GO:0032880]; regulation of stress fiber assembly [GO:0051492]; renal tubule development [GO:0061326]; sensory perception of smell [GO:0007608]; sensory processing [GO:0050893] GO:0001736; GO:0005813; GO:0005829; GO:0005929; GO:0007411; GO:0007608; GO:0015031; GO:0021772; GO:0032391; GO:0032880; GO:0034260; GO:0034464; GO:0035264; GO:0036064; GO:0045198; GO:0045444; GO:0048560; GO:0050893; GO:0051492; GO:0060122; GO:0060170; GO:0060219; GO:0060271; GO:0061326; GO:0061629; GO:0072659; GO:0097730; GO:1903251; GO:1905515 38996 XM_029335290.2 645 672 15 339 426 NA NA NA NA NA NA 38997 XR_006393247.1 378 265 283 323 420 NA NA NA NA NA NA 38998 XM_044314483.1 0 17 12 611 0 NA NA NA NA NA NA 38999 XM_044316444.1 0 3 3 2 6 NA NA NA NA NA NA 39000 XM_029354027.2 0 0 5 21 42 NA NA NA NA NA NA 39001 XM_044312241.1 0 0 18 4 1 NA NA NA NA NA NA 39002 XM_044322737.1 368 166 232 603 259 NA NA NA NA NA NA 39003 XM_029331916.2 88 286 134 0 65 Q58D84 7.97e-68 Follistatin-related protein 1 (Follistatin-like protein 1) Bos taurus (Bovine) cell differentiation [GO:0030154]; endothelial cell differentiation [GO:0045446]; endothelial cell migration [GO:0043542]; negative regulation of apoptotic process [GO:0043066]; regulation of BMP signaling pathway [GO:0030510] GO:0005509; GO:0005576; GO:0008201; GO:0030154; GO:0030510; GO:0043066; GO:0043542; GO:0045446 39004 XM_029333911.2 1107 1180 978 1546 993 NA NA NA NA NA NA 39005 XM_044310118.1 0 0 0 221 0 NA NA NA NA NA NA 39006 XM_044328205.1 121 108 100 86 70 Q62867 1.59e-70 Gamma-glutamyl hydrolase (EC 3.4.19.9) (Conjugase) (GH) (Gamma-Glu-X carboxypeptidase) Rattus norvegicus (Rat) poly-gamma-glutamate metabolic process [GO:0070500]; response to ethanol [GO:0045471]; response to insulin [GO:0032868]; response to xenobiotic stimulus [GO:0009410]; response to zinc ion [GO:0010043]; tetrahydrofolylpolyglutamate metabolic process [GO:0046900] GO:0005615; GO:0005764; GO:0005773; GO:0005829; GO:0009410; GO:0010043; GO:0032868; GO:0034722; GO:0042470; GO:0045471; GO:0046900; GO:0070500 39007 XM_044316257.1 57 22 11 35 33 Q3UFF7 2.99e-36 Lysophospholipase-like protein 1 (EC 3.1.2.22) Mus musculus (Mouse) negative regulation of Golgi to plasma membrane protein transport [GO:0042997]; protein depalmitoylation [GO:0002084] GO:0002084; GO:0005737; GO:0005829; GO:0008474; GO:0042997 39008 XM_044317929.1 257 174 152 257 296 Q12933 7.85e-55 TNF receptor-associated factor 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF2) (RING-type E3 ubiquitin transferase TRAF2) (Tumor necrosis factor type 2 receptor-associated protein 3) Homo sapiens (Human) activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular response to nitric oxide [GO:0071732]; interleukin-17-mediated signaling pathway [GO:0097400]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; mRNA stabilization [GO:0048255]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron death [GO:1901215]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein K63-linked ubiquitination [GO:0070534]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin production [GO:0002637]; regulation of protein-containing complex assembly [GO:0043254]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; signal transduction involved in regulation of gene expression [GO:0023019]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000151; GO:0002637; GO:0002726; GO:0002947; GO:0004842; GO:0005164; GO:0005174; GO:0005654; GO:0005829; GO:0005938; GO:0007165; GO:0007250; GO:0008270; GO:0009898; GO:0012506; GO:0019899; GO:0019901; GO:0019903; GO:0023019; GO:0030163; GO:0030674; GO:0031435; GO:0031625; GO:0031996; GO:0032743; GO:0033209; GO:0034351; GO:0034976; GO:0035631; GO:0042802; GO:0042981; GO:0043120; GO:0043122; GO:0043123; GO:0043254; GO:0043507; GO:0044877; GO:0045121; GO:0046330; GO:0046625; GO:0048255; GO:0051091; GO:0051092; GO:0051865; GO:0065003; GO:0070059; GO:0070534; GO:0071732; GO:0097057; GO:0097300; GO:0097400; GO:1901215; GO:1903265; GO:1903721; GO:1990604; GO:2001238 39009 XM_029340638.2 310 368 230 312 310 NA NA NA NA NA NA 39010 XM_044307675.1 62 46 74 46 90 NA NA NA NA NA NA 39011 XR_003827943.2 45 56 19 17 31 NA NA NA NA NA NA 39012 XM_029352532.2 140 120 122 121 102 Q9EQG7 1.73e-114 Ectonucleotide pyrophosphatase/phosphodiesterase family member 5 (E-NPP 5) (NPP-5) (EC 3.1.-.-) Mus musculus (Mouse) cell communication [GO:0007154]; nucleotide catabolic process [GO:0009166] GO:0000210; GO:0004551; GO:0005576; GO:0005886; GO:0007154; GO:0008270; GO:0009166; GO:0016020 39013 XM_044311093.1 3 107 0 0 10 NA NA NA NA NA NA 39014 XR_006393621.1 35 34 18 28 48 NA NA NA NA NA NA 39015 XM_044320406.1 157 42 50 0 0 NA NA NA NA NA NA 39016 XM_044317762.1 73 0 0 0 0 O43435 4.73e-102 T-box transcription factor TBX1 (T-box protein 1) (Testis-specific T-box protein) Homo sapiens (Human) angiogenesis [GO:0001525]; anterior/posterior pattern specification [GO:0009952]; aorta morphogenesis [GO:0035909]; artery morphogenesis [GO:0048844]; blood vessel development [GO:0001568]; blood vessel morphogenesis [GO:0048514]; cell fate specification [GO:0001708]; cell population proliferation [GO:0008283]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to retinoic acid [GO:0071300]; cochlea morphogenesis [GO:0090103]; coronary artery morphogenesis [GO:0060982]; determination of left/right symmetry [GO:0007368]; ear morphogenesis [GO:0042471]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic viscerocranium morphogenesis [GO:0048703]; enamel mineralization [GO:0070166]; epithelial cell differentiation [GO:0030855]; face morphogenesis [GO:0060325]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; inner ear morphogenesis [GO:0042472]; lymph vessel development [GO:0001945]; mesenchymal cell apoptotic process [GO:0097152]; mesoderm development [GO:0007498]; middle ear morphogenesis [GO:0042474]; muscle cell fate commitment [GO:0042693]; muscle organ development [GO:0007517]; muscle organ morphogenesis [GO:0048644]; muscle tissue morphogenesis [GO:0060415]; negative regulation of cell differentiation [GO:0045596]; negative regulation of mesenchymal cell apoptotic process [GO:2001054]; neural crest cell migration [GO:0001755]; odontogenesis of dentin-containing tooth [GO:0042475]; outer ear morphogenesis [GO:0042473]; outflow tract morphogenesis [GO:0003151]; outflow tract septum morphogenesis [GO:0003148]; parathyroid gland development [GO:0060017]; pattern specification process [GO:0007389]; pharyngeal system development [GO:0060037]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of tongue muscle cell differentiation [GO:2001037]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of animal organ morphogenesis [GO:2000027]; regulation of transcription by RNA polymerase II [GO:0006357]; retinoic acid receptor signaling pathway [GO:0048384]; semicircular canal morphogenesis [GO:0048752]; sensory perception of sound [GO:0007605]; social behavior [GO:0035176]; soft palate development [GO:0060023]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; tongue morphogenesis [GO:0043587]; vagus nerve morphogenesis [GO:0021644] GO:0000785; GO:0000978; GO:0000981; GO:0001525; GO:0001568; GO:0001708; GO:0001755; GO:0001934; GO:0001945; GO:0002053; GO:0003007; GO:0003148; GO:0003151; GO:0003677; GO:0005634; GO:0006357; GO:0007368; GO:0007389; GO:0007498; GO:0007507; GO:0007517; GO:0007605; GO:0008283; GO:0008284; GO:0009952; GO:0021644; GO:0030855; GO:0030878; GO:0035176; GO:0035909; GO:0042471; GO:0042472; GO:0042473; GO:0042474; GO:0042475; GO:0042693; GO:0042803; GO:0043410; GO:0043565; GO:0043587; GO:0044344; GO:0045596; GO:0045893; GO:0045944; GO:0046983; GO:0048384; GO:0048514; GO:0048538; GO:0048644; GO:0048701; GO:0048703; GO:0048752; GO:0048844; GO:0050679; GO:0060017; GO:0060023; GO:0060037; GO:0060325; GO:0060415; GO:0060982; GO:0070166; GO:0071300; GO:0090103; GO:0097152; GO:1990837; GO:2000027; GO:2001037; GO:2001054 39017 XM_044321583.1 15 43 25 3 29 NA NA NA NA NA NA 39018 XM_029336939.2 137 94 147 113 235 Q94887 2.41e-36 Neurexin-4 (Neurexin IV) Drosophila melanogaster (Fruit fly) axon ensheathment [GO:0008366]; cell adhesion involved in heart morphogenesis [GO:0061343]; cell-cell junction organization [GO:0045216]; dorsal closure [GO:0007391]; establishment of glial blood-brain barrier [GO:0060857]; heart process [GO:0003015]; nerve maturation [GO:0021682]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]; synaptic target recognition [GO:0008039]; terminal button organization [GO:0072553] GO:0003015; GO:0005886; GO:0005919; GO:0007391; GO:0008039; GO:0008104; GO:0008366; GO:0019991; GO:0021682; GO:0035151; GO:0045202; GO:0045216; GO:0048786; GO:0060857; GO:0061343; GO:0072553; GO:0097105 39019 XR_006393440.1 79 77 185 76 114 Q9HAV4 2.87e-35 Exportin-5 (Exp5) (Ran-binding protein 21) Homo sapiens (Human) miRNA metabolic process [GO:0010586]; positive regulation of post-transcriptional gene silencing by RNA [GO:1900370]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; RNA export from nucleus [GO:0006405] GO:0000049; GO:0003723; GO:0003729; GO:0005049; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006405; GO:0006611; GO:0010586; GO:0016442; GO:0031267; GO:0035281; GO:0042565; GO:0070883; GO:1900370; GO:1905172 39020 XM_029330019.2 53 87 169 229 234 NA NA NA NA NA NA 39021 XM_044328384.1 7 0 4 0 11 NA NA NA NA NA NA 39022 XM_029344047.2 1075 1695 481 555 772 Q91YY4 5.69e-75 ATP synthase mitochondrial F1 complex assembly factor 2 Mus musculus (Mouse) mitochondrial proton-transporting ATP synthase complex assembly [GO:0033615] GO:0005739; GO:0005829; GO:0016607; GO:0033615 39023 XR_006394961.1 0 2 0 4 38 NA NA NA NA NA NA 39024 XM_044323043.1 340 546 378 141 182 NA NA NA NA NA NA 39025 XM_044326181.1 13 51 7 31 58 NA NA NA NA NA NA 39026 XM_029325972.2 16 0 8 152 262 Q9HF54 5.28e-41 GTP-binding protein RHO1 Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii) actin filament organization [GO:0007015]; cortical cytoskeleton organization [GO:0030865]; establishment or maintenance of cell polarity [GO:0007163]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; small GTPase mediated signal transduction [GO:0007264] GO:0003924; GO:0005525; GO:0005856; GO:0005886; GO:0005938; GO:0007015; GO:0007163; GO:0007264; GO:0008360; GO:0019901; GO:0030865; GO:0031410; GO:0032956; GO:0042995 39027 XM_044309982.1 0 0 6 0 2 NA NA NA NA NA NA 39028 XM_029328068.2 0 0 18 36 18 NA NA NA NA NA NA 39029 XR_006391946.1 0 0 10 2 0 NA NA NA NA NA NA 39030 XM_044328286.1 0 0 0 17 38 Q7ZX59 6.74e-52 Cytokine receptor-like factor 3 Xenopus laevis (African clawed frog) NA GO:0005737 39031 XM_044324537.1 0 1 7 0 7 NA NA NA NA NA NA 39032 XM_029352296.2 460 175 191 216 408 Q9QZN1 6.17e-54 F-box/LRR-repeat protein 17 (F-box and leucine-rich repeat protein 17) (F-box only protein 13) Mus musculus (Mouse) entrainment of circadian clock by photoperiod [GO:0043153]; G2/M transition of mitotic cell cycle [GO:0000086]; nervous system development [GO:0007399]; neural crest cell differentiation [GO:0014033]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; protein ubiquitination [GO:0016567]; regulation of cell cycle [GO:0051726]; regulation of smoothened signaling pathway [GO:0008589]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0000086; GO:0000209; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006515; GO:0007399; GO:0008589; GO:0014033; GO:0016567; GO:0019005; GO:0031146; GO:0043153; GO:0043161; GO:0051726 39033 XM_029351959.2 367 480 419 392 258 Q06546 1.16e-58 GA-binding protein alpha chain (GABP subunit alpha) (Nuclear respiratory factor 2 subunit alpha) (Transcription factor E4TF1-60) Homo sapiens (Human) blastocyst formation [GO:0001825]; cell differentiation [GO:0030154]; cellular response to dopamine [GO:1903351]; negative regulation of megakaryocyte differentiation [GO:0045653]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000785; GO:0000976; GO:0000978; GO:0000981; GO:0001228; GO:0001825; GO:0003682; GO:0003700; GO:0005634; GO:0005654; GO:0006357; GO:0010628; GO:0030154; GO:0045653; GO:0045944; GO:1903351; GO:1990837 39034 XM_029330454.2 129 277 211 277 134 NA NA NA NA NA NA 39035 XM_029356434.2 223 10 40 52 129 Q6A548 5.09e-117 Telomerase reverse transcriptase (EC 2.7.7.49) (Telomerase catalytic subunit) Canis lupus familiaris (Dog) (Canis familiaris) telomere maintenance via telomerase [GO:0007004] GO:0000333; GO:0000781; GO:0003720; GO:0003721; GO:0005697; GO:0005730; GO:0005737; GO:0007004; GO:0016605; GO:0042162; GO:0046872; GO:0070034 39036 XM_029356434.2 223 10 40 52 129 Q6A548 2.01e-22 Telomerase reverse transcriptase (EC 2.7.7.49) (Telomerase catalytic subunit) Canis lupus familiaris (Dog) (Canis familiaris) telomere maintenance via telomerase [GO:0007004] GO:0000333; GO:0000781; GO:0003720; GO:0003721; GO:0005697; GO:0005730; GO:0005737; GO:0007004; GO:0016605; GO:0042162; GO:0046872; GO:0070034 39037 XR_006394370.1 21 19 17 45 128 NA NA NA NA NA NA 39038 XR_006395498.1 190 199 22 45 30 NA NA NA NA NA NA 39039 XR_006393997.1 3 3 6 0 54 NA NA NA NA NA NA 39040 XM_044325618.1 801 720 486 822 780 A8NIX5 4.31e-23 Uncharacterized protein C2orf81 homolog Bos taurus (Bovine) NA NA 39041 XM_029358566.2 31 92 196 21 59 B3EWY8 2.51e-29 Skeletal aspartic acid-rich protein 2 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 39042 XM_044320032.1 0 42 8 46 26 Q9NU02 0 Ankyrin repeat and EF-hand domain-containing protein 1 (Ankyrin repeat domain-containing protein 5) Homo sapiens (Human) NA GO:0005509 39043 XM_029353137.2 34 25 21 43 106 E7FAM5 3.59e-54 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 39044 XM_029333287.2 9 0 30 0 34 P83858 4.38e-27 Pyroglutamylated RF-amide peptide receptor (AQ27) (G-protein coupled receptor 103) (Orexigenic neuropeptide QRFP receptor) (SP9155) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:0097730 39045 XM_044316575.1 3 2 5 0 16 NA NA NA NA NA NA 39046 XM_029346599.2 640 207 154 306 185 NA NA NA NA NA NA 39047 XM_029345259.2 71 41 39 74 23 Q9Z0E8 9.22e-82 Organic cation/carnitine transporter 2 (High-affinity sodium-dependent carnitine cotransporter) (Solute carrier family 22 member 5) Mus musculus (Mouse) (R)-carnitine transmembrane transport [GO:1902270]; (R)-carnitine transport [GO:1900749]; adult heart development [GO:0007512]; carnitine metabolic process [GO:0009437]; carnitine transport [GO:0015879]; establishment of localization in cell [GO:0051649]; locomotory behavior [GO:0007626]; mitochondrion organization [GO:0007005]; positive regulation of intestinal epithelial structure maintenance [GO:0060731]; quaternary ammonium group transport [GO:0015697]; reproductive structure development [GO:0048608]; response to symbiotic bacterium [GO:0009609]; response to tumor necrosis factor [GO:0034612]; response to type II interferon [GO:0034341]; sodium ion transport [GO:0006814]; sodium-dependent organic cation transport [GO:0070715]; transport across blood-brain barrier [GO:0150104] GO:0005524; GO:0005737; GO:0005783; GO:0005829; GO:0005886; GO:0006814; GO:0007005; GO:0007512; GO:0007626; GO:0009437; GO:0009609; GO:0009925; GO:0015226; GO:0015293; GO:0015651; GO:0015697; GO:0015879; GO:0016020; GO:0016323; GO:0016324; GO:0030165; GO:0031526; GO:0034341; GO:0034612; GO:0048608; GO:0051649; GO:0060731; GO:0070715; GO:0150104; GO:1900749; GO:1901235; GO:1902270 39048 XR_006397348.1 111 200 387 164 611 NA NA NA NA NA NA 39049 XM_044316499.1 125 6 33 186 75 NA NA NA NA NA NA 39050 XM_029325318.2 220 179 158 177 130 P38487 0 Creatinase (EC 3.5.3.3) (Creatine amidinohydrolase) Bacillus sp. (strain B-0618) NA GO:0016980 39051 XM_044327065.1 195 17 34 136 30 NA NA NA NA NA NA 39052 XM_044308364.1 34 10 17 49 46 NA NA NA NA NA NA 39053 XM_029343472.2 38 53 15 52 45 NA NA NA NA NA NA 39054 XM_044313576.1 0 0 9 0 0 NA NA NA NA NA NA 39055 XM_029358055.2 89 7 41 19 72 Q9W0Y2 1.09e-28 Putative gamma-glutamylcyclotransferase CG2811 (EC 2.3.2.-) Drosophila melanogaster (Fruit fly) NA GO:0005829; GO:0016746; GO:0061929 39056 XM_044324239.1 0 122 0 71 0 NA NA NA NA NA NA 39057 XM_044317212.1 73 368 137 611 138 P08684 7.02e-95 Cytochrome P450 3A4 (EC 1.14.14.1) (1,4-cineole 2-exo-monooxygenase) (1,8-cineole 2-exo-monooxygenase) (EC 1.14.14.56) (Albendazole monooxygenase (sulfoxide-forming)) (EC 1.14.14.73) (Albendazole sulfoxidase) (CYPIIIA3) (CYPIIIA4) (Cholesterol 25-hydroxylase) (Cytochrome P450 3A3) (Cytochrome P450 HLp) (Cytochrome P450 NF-25) (Cytochrome P450-PCN1) (Nifedipine oxidase) (Quinine 3-monooxygenase) (EC 1.14.14.55) Homo sapiens (Human) aflatoxin metabolic process [GO:0046222]; alkaloid catabolic process [GO:0009822]; androgen metabolic process [GO:0008209]; cholesterol metabolic process [GO:0008203]; estrogen metabolic process [GO:0008210]; heterocycle metabolic process [GO:0046483]; lipid hydroxylation [GO:0002933]; lipid metabolic process [GO:0006629]; long-chain fatty acid biosynthetic process [GO:0042759]; monoterpenoid metabolic process [GO:0016098]; oxidative demethylation [GO:0070989]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]; steroid catabolic process [GO:0006706]; steroid metabolic process [GO:0008202]; vitamin D catabolic process [GO:0042369]; vitamin D metabolic process [GO:0042359]; xenobiotic catabolic process [GO:0042178]; xenobiotic metabolic process [GO:0006805] GO:0002933; GO:0004497; GO:0005496; GO:0005506; GO:0005737; GO:0005789; GO:0006629; GO:0006706; GO:0006805; GO:0008202; GO:0008203; GO:0008209; GO:0008210; GO:0008395; GO:0008401; GO:0009822; GO:0016098; GO:0016491; GO:0019825; GO:0019899; GO:0020037; GO:0030343; GO:0034875; GO:0042178; GO:0042359; GO:0042369; GO:0042572; GO:0042573; GO:0042759; GO:0043231; GO:0046222; GO:0046483; GO:0050591; GO:0050649; GO:0062181; GO:0062187; GO:0062188; GO:0062189; GO:0070330; GO:0070576; GO:0070989; GO:0101020; GO:0101021; GO:0102320 39058 XM_029337890.2 0 0 0 987 1426 NA NA NA NA NA NA 39059 XM_044309699.1 0 14 0 0 13 NA NA NA NA NA NA 39060 XM_029337405.2 62 0 8 71 39 Q9Z1T2 6.73e-177 Thrombospondin-4 Mus musculus (Mouse) behavioral response to pain [GO:0048266]; endothelial cell-cell adhesion [GO:0071603]; myoblast migration [GO:0051451]; negative regulation of angiogenesis [GO:0016525]; nervous system development [GO:0007399]; neuron projection morphogenesis [GO:0048812]; positive regulation of cell division [GO:0051781]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of tissue remodeling [GO:0034103]; response to endoplasmic reticulum stress [GO:0034976]; response to unfolded protein [GO:0006986]; tissue remodeling [GO:0048771] GO:0001938; GO:0001968; GO:0005178; GO:0005509; GO:0005518; GO:0005604; GO:0005615; GO:0005783; GO:0006986; GO:0007399; GO:0008083; GO:0008201; GO:0016525; GO:0016529; GO:0031012; GO:0031594; GO:0034103; GO:0034976; GO:0042802; GO:0043237; GO:0048266; GO:0048771; GO:0048812; GO:0050731; GO:0051451; GO:0051781; GO:0062023; GO:0071603; GO:0090023 39061 XM_044327866.1 0 0 0 0 19 NA NA NA NA NA NA 39062 XM_029331303.2 55 27 22 23 4 Q6P2X9 2.7e-41 Monocarboxylate transporter 12 (MCT 12) (Solute carrier family 16 member 12) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) creatine transmembrane transport [GO:0015881]; creatinine metabolic process [GO:0046449] GO:0005308; GO:0005886; GO:0015292; GO:0015881; GO:0016323; GO:0046449 39063 XM_029341682.2 96 46 222 269 204 P05132 0 cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11) Mus musculus (Mouse) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cellular response to cold [GO:0070417]; cellular response to glucose stimulus [GO:0071333]; cellular response to heat [GO:0034605]; cellular response to parathyroid hormone stimulus [GO:0071374]; mesoderm formation [GO:0001707]; modulation of chemical synaptic transmission [GO:0050804]; mRNA processing [GO:0006397]; negative regulation of meiotic cell cycle [GO:0051447]; negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:1901621]; neural tube closure [GO:0001843]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of insulin secretion [GO:0032024]; positive regulation of protein export from nucleus [GO:0046827]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; protein autophosphorylation [GO:0046777]; protein export from nucleus [GO:0006611]; protein kinase A signaling [GO:0010737]; protein localization to lipid droplet [GO:1990044]; protein phosphorylation [GO:0006468]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of cell cycle [GO:0051726]; regulation of cellular respiration [GO:0043457]; regulation of osteoblast differentiation [GO:0045667]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of protein processing [GO:0070613]; regulation of synaptic transmission, glutamatergic [GO:0051966]; sperm capacitation [GO:0048240]; spontaneous exocytosis of neurotransmitter [GO:0048792] GO:0000287; GO:0001669; GO:0001707; GO:0001843; GO:0004672; GO:0004674; GO:0004679; GO:0004691; GO:0004712; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005794; GO:0005813; GO:0005829; GO:0005886; GO:0005930; GO:0005952; GO:0006397; GO:0006468; GO:0006611; GO:0007189; GO:0008284; GO:0010737; GO:0016020; GO:0016607; GO:0018105; GO:0018107; GO:0019901; GO:0019904; GO:0030145; GO:0031267; GO:0031588; GO:0031594; GO:0031625; GO:0032024; GO:0032991; GO:0034237; GO:0034605; GO:0036126; GO:0043005; GO:0043197; GO:0043457; GO:0044853; GO:0044877; GO:0045667; GO:0046777; GO:0046827; GO:0048240; GO:0048471; GO:0048792; GO:0050804; GO:0051447; GO:0051726; GO:0051966; GO:0061136; GO:0070417; GO:0070613; GO:0071333; GO:0071374; GO:0097225; GO:0097546; GO:0098793; GO:0098794; GO:0098978; GO:0099170; GO:0106310; GO:1901621; GO:1990044; GO:2000810 39064 XR_006396472.1 47 20 79 28 261 NA NA NA NA NA NA 39065 XM_029344717.2 192 278 206 145 266 NA NA NA NA NA NA 39066 XR_006396267.1 3713 2624 2110 2724 2181 NA NA NA NA NA NA 39067 XR_006392298.1 622 235 67 60 316 NA NA NA NA NA NA 39068 XM_029332951.2 50 9 114 510 247 NA NA NA NA NA NA 39069 XM_029353616.2 15 37 3 408 46 P0CT40 5.34e-64 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 39070 XM_029340912.2 1 21 19 4 6 NA NA NA NA NA NA 39071 XM_029334302.2 1635 1510 903 1096 1758 Q5E9U9 1.19e-131 GATOR complex protein NPRL2 (Nitrogen permease regulator 2-like protein) (NPR2-like protein) Bos taurus (Bovine) cellular response to amino acid starvation [GO:0034198]; negative regulation of TORC1 signaling [GO:1904262]; positive regulation of autophagy [GO:0010508] GO:0005096; GO:0005765; GO:0005774; GO:0010508; GO:0034198; GO:1904262; GO:1990130 39072 XM_044326715.1 670 155 108 404 87 NA NA NA NA NA NA 39073 XM_029352400.2 222 454 344 480 389 Q9H267 1.36e-177 Vacuolar protein sorting-associated protein 33B (hVPS33B) Homo sapiens (Human) collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; endosome organization [GO:0007032]; intracellular protein transport [GO:0006886]; intracellular transport [GO:0046907]; lysosome localization [GO:0032418]; megakaryocyte development [GO:0035855]; melanosome localization [GO:0032400]; membrane fusion [GO:0061025]; peptidyl-lysine hydroxylation [GO:0017185]; phagosome-lysosome fusion [GO:0090385]; platelet alpha granule organization [GO:0070889]; protein transport [GO:0015031]; regulation of platelet aggregation [GO:0090330]; vesicle-mediated transport [GO:0016192] GO:0005737; GO:0005764; GO:0005765; GO:0005768; GO:0005770; GO:0005773; GO:0005794; GO:0005829; GO:0006886; GO:0007032; GO:0010008; GO:0015031; GO:0016192; GO:0017185; GO:0030136; GO:0030199; GO:0030897; GO:0031091; GO:0031901; GO:0031902; GO:0032400; GO:0032418; GO:0032963; GO:0033263; GO:0035855; GO:0044877; GO:0046907; GO:0048471; GO:0055037; GO:0061025; GO:0070889; GO:0090330; GO:0090385; GO:0099023 39074 XM_029334987.2 10 10 14 17 39 P97292 4.01e-27 Histamine H2 receptor (H2R) (HH2R) (Gastric receptor I) Mus musculus (Mouse) chemical synaptic transmission [GO:0007268]; digestive tract development [GO:0048565]; epithelial cell morphogenesis [GO:0003382]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; gastric acid secretion [GO:0001696]; gastrin-induced gastric acid secretion [GO:0001698]; gland development [GO:0048732]; histamine-induced gastric acid secretion [GO:0001697]; memory [GO:0007613]; negative regulation of arachidonic acid secretion [GO:1900139]; positive regulation of vasoconstriction [GO:0045907]; regulation of synaptic plasticity [GO:0048167]; toxin transport [GO:1901998]; visual learning [GO:0008542] GO:0001696; GO:0001697; GO:0001698; GO:0003382; GO:0004969; GO:0004993; GO:0005886; GO:0007187; GO:0007268; GO:0007613; GO:0008542; GO:0016020; GO:0030425; GO:0030594; GO:0045202; GO:0045907; GO:0048167; GO:0048565; GO:0048732; GO:1900139; GO:1901363; GO:1901998 39075 XM_029334274.2 63 0 0 0 0 P25931 2.8e-34 RYamide receptor (Neuropeptide Y-like receptor) (NPY-R) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218] GO:0001653; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0016020 39076 XM_044312636.1 143 134 120 107 287 NA NA NA NA NA NA 39077 XR_006391727.1 58 40 5 38 18 NA NA NA NA NA NA 39078 XM_044321336.1 18 20 4 26 45 B3EWZ5 2.37e-22 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 39079 XM_044321336.1 18 20 4 26 45 B3EWZ5 3.27e-22 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 39080 XM_044321336.1 18 20 4 26 45 B3EWZ5 1.55e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 39081 XM_044321336.1 18 20 4 26 45 B3EWZ5 1.65e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 39082 XM_044321336.1 18 20 4 26 45 B3EWZ5 4.33e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 39083 XM_044321336.1 18 20 4 26 45 B3EWZ5 9.66e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 39084 XM_029331508.2 497 377 329 400 275 NA NA NA NA NA NA 39085 XM_044317726.1 257 311 6 385 414 NA NA NA NA NA NA 39086 XM_044314448.1 722 982 655 1088 635 NA NA NA NA NA NA 39087 XM_044325027.1 26 9 2 24 9 NA NA NA NA NA NA 39088 XM_044326152.1 5 0 0 3 23 NA NA NA NA NA NA 39089 XM_044318756.1 0 0 0 24 136 NA NA NA NA NA NA 39090 XM_029338938.2 268 325 241 287 368 Q8K4L0 0 ATP-dependent RNA helicase DDX54 (EC 3.6.4.13) (DEAD box protein 54) Mus musculus (Mouse) RNA metabolic process [GO:0016070]; RNA processing [GO:0006396]; rRNA processing [GO:0006364] GO:0003714; GO:0003723; GO:0003724; GO:0005102; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005794; GO:0006364; GO:0006396; GO:0016070; GO:0016887; GO:0030331 39091 XM_029351119.2 921 526 529 685 626 NA NA NA NA NA NA 39092 XM_029330232.2 434 149 70 190 488 Q6PCN7 0 Helicase-like transcription factor (EC 2.3.2.27) (EC 3.6.4.-) (P113) (RING-type E3 ubiquitin transferase HLTF) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) Mus musculus (Mouse) DNA repair [GO:0006281]; mRNA transcription by RNA polymerase II [GO:0042789]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of neurogenesis [GO:0050767] GO:0003677; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0006281; GO:0008094; GO:0008270; GO:0016363; GO:0016818; GO:0031625; GO:0042789; GO:0045944; GO:0050767; GO:0061630; GO:0090575; GO:0140658 39093 XM_044308276.1 461 349 544 701 489 Q8K385 2.36e-41 Ferric-chelate reductase 1 (EC 1.-.-.-) (Stromal cell-derived receptor 2) (SDR-2) Mus musculus (Mouse) cellular iron ion homeostasis [GO:0006879] GO:0006879; GO:0016020; GO:0016722; GO:0046872 39094 XM_044308276.1 461 349 544 701 489 Q8K385 9.2e-23 Ferric-chelate reductase 1 (EC 1.-.-.-) (Stromal cell-derived receptor 2) (SDR-2) Mus musculus (Mouse) cellular iron ion homeostasis [GO:0006879] GO:0006879; GO:0016020; GO:0016722; GO:0046872 39095 XM_029357928.2 2 0 5 14 76 NA NA NA NA NA NA 39096 XM_029324412.2 1044 742 846 526 677 Q96KN3 4.14e-43 Homeobox protein PKNOX2 (Homeobox protein PREP-2) (PBX/knotted homeobox 2) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0003785; GO:0005654; GO:0005737; GO:0006357; GO:0015629; GO:0015630; GO:0045171; GO:0051015; GO:1990837 39097 XM_029324412.2 1044 742 846 526 677 Q96KN3 7.42e-41 Homeobox protein PKNOX2 (Homeobox protein PREP-2) (PBX/knotted homeobox 2) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0003785; GO:0005654; GO:0005737; GO:0006357; GO:0015629; GO:0015630; GO:0045171; GO:0051015; GO:1990837 39098 XM_044329036.1 310 210 170 339 417 NA NA NA NA NA NA 39099 XR_006396812.1 18 15 30 17 73 NA NA NA NA NA NA 39100 XM_044314882.1 14 6 11 16 13 NA NA NA NA NA NA 39101 XM_044311765.1 0 0 0 0 7 NA NA NA NA NA NA 39102 XR_006393196.1 1 3 16 0 40 NA NA NA NA NA NA 39103 XM_029348744.2 75 39 13 60 130 Q9UJX3 6.42e-121 Anaphase-promoting complex subunit 7 (APC7) (Cyclosome subunit 7) Homo sapiens (Human) anaphase-promoting complex-dependent catabolic process [GO:0031145]; brain development [GO:0007420]; cell division [GO:0051301]; metaphase/anaphase transition of mitotic cell cycle [GO:0007091]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; protein K11-linked ubiquitination [GO:0070979]; protein ubiquitination [GO:0016567]; regulation of meiotic cell cycle [GO:0051445]; regulation of mitotic cell cycle [GO:0007346] GO:0000792; GO:0005634; GO:0005654; GO:0005680; GO:0005737; GO:0005819; GO:0005829; GO:0007091; GO:0007346; GO:0007420; GO:0015630; GO:0016567; GO:0019903; GO:0031145; GO:0045842; GO:0051301; GO:0051445; GO:0070979; GO:0140767 39104 XM_029337119.2 42 19 51 35 215 NA NA NA NA NA NA 39105 XM_029357076.2 10 0 0 0 0 Q3TUA9 1.72e-45 Protein O-mannose kinase (POMK) (EC 2.7.1.183) (Protein kinase-like protein SgK196) (Sugen kinase 196) Mus musculus (Mouse) brain development [GO:0007420]; carbohydrate phosphorylation [GO:0046835]; learning or memory [GO:0007611]; neuromuscular process [GO:0050905]; protein O-linked glycosylation [GO:0006493]; protein phosphorylation [GO:0006468]; sensory perception of pain [GO:0019233] GO:0004672; GO:0005524; GO:0005789; GO:0006468; GO:0006493; GO:0007420; GO:0007611; GO:0016773; GO:0019200; GO:0019233; GO:0046835; GO:0050905 39106 XM_029356545.2 1112 478 475 913 618 NA NA NA NA NA NA 39107 XM_044311077.1 66 37 46 147 93 NA NA NA NA NA NA 39108 XM_044313742.1 0 0 0 15 3 Q9JME2 6.63e-42 Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4S-1) (C4ST-1) (C4ST1) Mus musculus (Mouse) apoptotic process [GO:0006915]; carbohydrate biosynthetic process [GO:0016051]; cartilage development [GO:0051216]; chondrocyte development [GO:0002063]; chondroitin sulfate biosynthetic process [GO:0030206]; chondroitin sulfate metabolic process [GO:0030204]; developmental growth [GO:0048589]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; embryonic viscerocranium morphogenesis [GO:0048703]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; polysaccharide localization [GO:0033037]; post-anal tail morphogenesis [GO:0036342]; post-embryonic development [GO:0009791]; proteoglycan biosynthetic process [GO:0030166]; regulation of cell population proliferation [GO:0042127]; respiratory gaseous exchange by respiratory system [GO:0007585]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0000139; GO:0001537; GO:0001701; GO:0002063; GO:0006915; GO:0007179; GO:0007585; GO:0008146; GO:0009791; GO:0016051; GO:0030166; GO:0030204; GO:0030206; GO:0030326; GO:0030512; GO:0033037; GO:0036342; GO:0042127; GO:0042733; GO:0043066; GO:0047756; GO:0048589; GO:0048703; GO:0048704; GO:0050659; GO:0051216 39109 XR_006394122.1 335 132 244 135 439 NA NA NA NA NA NA 39110 XM_029342166.2 0 0 306 0 378 Q96L93 4.53e-104 Kinesin-like protein KIF16B (Sorting nexin-23) Homo sapiens (Human) early endosome to late endosome transport [GO:0045022]; endoderm development [GO:0007492]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; formation of primary germ layer [GO:0001704]; Golgi to endosome transport [GO:0006895]; microtubule-based movement [GO:0007018]; receptor catabolic process [GO:0032801]; regulation of receptor recycling [GO:0001919] GO:0001704; GO:0001919; GO:0003777; GO:0005524; GO:0005547; GO:0005737; GO:0005768; GO:0005769; GO:0005819; GO:0005829; GO:0005871; GO:0005874; GO:0006895; GO:0007018; GO:0007173; GO:0007492; GO:0008017; GO:0008543; GO:0008574; GO:0016887; GO:0031901; GO:0032266; GO:0032801; GO:0043325; GO:0045022; GO:0080025 39111 XM_044320272.1 229 55 3 127 96 NA NA NA NA NA NA 39112 XM_029344792.2 789 582 334 184 573 Q8N2Z9 7.57e-30 Centromere protein S (CENP-S) (Apoptosis-inducing TAF9-like domain-containing protein 1) (FANCM-associated histone fold protein 1) (FANCM-interacting histone fold protein 1) (Fanconi anemia-associated polypeptide of 16 kDa) Homo sapiens (Human) cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; interstrand cross-link repair [GO:0036297]; positive regulation of protein ubiquitination [GO:0031398]; replication fork processing [GO:0031297]; resolution of meiotic recombination intermediates [GO:0000712] GO:0000712; GO:0000776; GO:0000785; GO:0003677; GO:0003682; GO:0005654; GO:0005829; GO:0006281; GO:0006974; GO:0031297; GO:0031398; GO:0036297; GO:0043240; GO:0046982; GO:0051301; GO:0071821 39113 XM_044327874.1 7 0 9 0 24 NA NA NA NA NA NA 39114 XM_029342614.2 0 1062 57 0 0 Q58A42 6.05e-73 Protein DD3-3 Dictyostelium discoideum (Social amoeba) NA GO:0016020 39115 XM_044321783.1 110 0 0 124 0 NA NA NA NA NA NA 39116 XM_029355668.2 1095 795 714 1450 557 NA NA NA NA NA NA 39117 XM_044308251.1 51 65 30 65 82 NA NA NA NA NA NA 39118 XR_006395227.1 15 0 30 0 77 NA NA NA NA NA NA 39119 XR_006397308.1 712 423 833 948 111 NA NA NA NA NA NA 39120 XM_044322780.1 26 52 43 40 32 P78357 2.86e-26 Contactin-associated protein 1 (Caspr) (Caspr1) (Neurexin IV) (Neurexin-4) (p190) Homo sapiens (Human) axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cytoskeleton organization [GO:0007010]; mitochondrion organization [GO:0007005]; myelination in peripheral nervous system [GO:0022011]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; neuron projection morphogenesis [GO:0048812]; neuronal action potential propagation [GO:0019227]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; postsynaptic density organization [GO:0097106]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; regulation of synapse maturation [GO:0090128]; signal transduction [GO:0007165] GO:0002175; GO:0005886; GO:0007005; GO:0007010; GO:0007155; GO:0007165; GO:0007409; GO:0016020; GO:0017124; GO:0019227; GO:0022010; GO:0022011; GO:0030913; GO:0033010; GO:0033270; GO:0038023; GO:0048786; GO:0048812; GO:0050884; GO:0050885; GO:0071205; GO:0090128; GO:0097106; GO:0098529; GO:0098978; GO:1990227 39121 XM_044317443.1 0 1 0 0 7 Q9UL62 2.28e-60 Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (TRP-5) (hTRP-5) (hTRP5) Homo sapiens (Human) calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; negative regulation of dendrite morphogenesis [GO:0050774]; nervous system development [GO:0007399]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; phosphatidylserine exposure on apoptotic cell surface [GO:0070782]; positive regulation of axon extension [GO:0045773]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of membrane hyperpolarization [GO:1902630] GO:0003779; GO:0005262; GO:0005737; GO:0005886; GO:0006816; GO:0007204; GO:0007399; GO:0008284; GO:0010800; GO:0015279; GO:0030182; GO:0030276; GO:0030425; GO:0030426; GO:0034703; GO:0034704; GO:0042805; GO:0043025; GO:0045121; GO:0045666; GO:0045773; GO:0050774; GO:0051117; GO:0051402; GO:0051480; GO:0070588; GO:0070679; GO:0070782; GO:1902630 39122 XM_029332925.2 7343 7519 5790 7591 6492 Q20655 8.73e-89 14-3-3-like protein 2 Caenorhabditis elegans cytoplasmic sequestering of protein [GO:0051220]; cytoplasmic sequestering of transcription factor [GO:0042994]; dauer larval development [GO:0040024]; maintenance of protein location in nucleus [GO:0051457]; negative regulation of gene expression [GO:0010629]; negative regulation of protein import into nucleus [GO:0042308]; regulation of gene expression [GO:0010468]; signal transduction [GO:0007165] GO:0005634; GO:0005737; GO:0007165; GO:0010468; GO:0010629; GO:0040024; GO:0042308; GO:0042994; GO:0051220; GO:0051457; GO:0140297 39123 XM_029335825.2 4 0 7 10 34 Q708S4 5.35e-32 Acid-sensing ion channel 4-A (ASIC4-A) (Acid-sensing ion channel 4.1) (Amiloride-sensitive cation channel 4-A) (ZASIC4.1) Danio rerio (Zebrafish) (Brachydanio rerio) sodium ion transmembrane transport [GO:0035725] GO:0005248; GO:0005261; GO:0005886; GO:0015280; GO:0035725; GO:0045177 39124 XM_044307199.1 601 674 529 710 626 Q9WVK8 5.16e-100 Cholesterol 24-hydroxylase (CH24H) (EC 1.14.14.25) (Cholesterol 24-monooxygenase) (Cholesterol 24S-hydroxylase) (Cytochrome P450 46A1) Mus musculus (Mouse) cholesterol catabolic process [GO:0006707]; progesterone metabolic process [GO:0042448]; protein localization to membrane raft [GO:1903044]; regulation of long-term synaptic potentiation [GO:1900271]; xenobiotic metabolic process [GO:0006805] GO:0005506; GO:0005789; GO:0006707; GO:0006805; GO:0008395; GO:0020037; GO:0030425; GO:0033781; GO:0042448; GO:0062184; GO:0098793; GO:0098794; GO:1900271; GO:1903044 39125 XM_029352035.2 2011 1547 897 1893 1712 Q08CH6 3.03e-73 Ciliogenesis-associated TTC17-interacting protein Danio rerio (Zebrafish) (Brachydanio rerio) actin filament polymerization [GO:0030041]; cilium assembly [GO:0060271]; cilium organization [GO:0044782]; determination of heart left/right asymmetry [GO:0061371] GO:0005634; GO:0005737; GO:0005886; GO:0015629; GO:0030041; GO:0044782; GO:0060271; GO:0061371 39126 XM_029335133.2 1491 838 559 2681 1351 NA NA NA NA NA NA 39127 XM_029339451.2 2 0 6 4 46 NA NA NA NA NA NA 39128 XM_044325704.1 0 235 0 0 661 Q12789 7.35e-72 General transcription factor 3C polypeptide 1 (TF3C-alpha) (TFIIIC box B-binding subunit) (Transcription factor IIIC 220 kDa subunit) (TFIIIC 220 kDa subunit) (TFIIIC220) (Transcription factor IIIC subunit alpha) Homo sapiens (Human) 5S class rRNA transcription by RNA polymerase III [GO:0042791]; rRNA transcription [GO:0009303]; transcription by RNA polymerase III [GO:0006383]; transcription initiation at RNA polymerase III promoter [GO:0006384]; tRNA transcription [GO:0009304]; tRNA transcription by RNA polymerase III [GO:0042797] GO:0000127; GO:0000995; GO:0003677; GO:0005654; GO:0005730; GO:0006383; GO:0006384; GO:0009303; GO:0009304; GO:0016020; GO:0042791; GO:0042797; GO:1990904 39129 XM_044325704.1 0 235 0 0 661 Q12789 3.74e-43 General transcription factor 3C polypeptide 1 (TF3C-alpha) (TFIIIC box B-binding subunit) (Transcription factor IIIC 220 kDa subunit) (TFIIIC 220 kDa subunit) (TFIIIC220) (Transcription factor IIIC subunit alpha) Homo sapiens (Human) 5S class rRNA transcription by RNA polymerase III [GO:0042791]; rRNA transcription [GO:0009303]; transcription by RNA polymerase III [GO:0006383]; transcription initiation at RNA polymerase III promoter [GO:0006384]; tRNA transcription [GO:0009304]; tRNA transcription by RNA polymerase III [GO:0042797] GO:0000127; GO:0000995; GO:0003677; GO:0005654; GO:0005730; GO:0006383; GO:0006384; GO:0009303; GO:0009304; GO:0016020; GO:0042791; GO:0042797; GO:1990904 39130 XM_029338888.2 29 139 12 114 149 NA NA NA NA NA NA 39131 XM_029357660.2 11 0 1 7 8 P48733 1.03e-28 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Bos taurus (Bovine) antibacterial innate immune response [GO:0140367]; defense response to Gram-negative bacterium [GO:0050829] GO:0000922; GO:0005201; GO:0005509; GO:0005576; GO:0005929; GO:0016020; GO:0016323; GO:0016324; GO:0031012; GO:0050829; GO:0060170; GO:0140367 39132 XM_029342081.2 689 483 383 403 159 Q9NP66 1.64e-62 High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein 1) (HMG domain-containing protein HMGX1) Homo sapiens (Human) chromatin organization [GO:0006325]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355]; regulation of gene expression [GO:0010468] GO:0000122; GO:0003677; GO:0005634; GO:0006325; GO:0006355; GO:0010468; GO:0033234; GO:0042802; GO:0045665 39133 XM_029357977.2 420 328 358 469 475 NA NA NA NA NA NA 39134 XM_029330058.2 0 18 0 0 33 A1L1W9 2.25e-47 Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10) Danio rerio (Zebrafish) (Brachydanio rerio) aromatic amino acid transport [GO:0015801]; thyroid hormone transport [GO:0070327] GO:0005302; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0070327 39135 XM_044317527.1 59 26 18 35 25 NA NA NA NA NA NA 39136 XM_044325329.1 23 23 20 82 55 A6QLU6 2.57e-65 Adhesion G-protein coupled receptor D1 (G-protein coupled receptor 133) Bos taurus (Bovine) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0005886; GO:0007166; GO:0007186; GO:0007189 39137 XR_006397120.1 34 29 43 27 44 NA NA NA NA NA NA 39138 XM_044312424.1 16 7 0 0 0 NA NA NA NA NA NA 39139 XM_029326614.2 611 499 483 1087 1398 Q9W735 2.86e-39 Prominin-1-A (Prominin-like protein 1) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005783; GO:0005793; GO:0005886; GO:0005902; GO:0005929; GO:0009986; GO:0015485; GO:0016324; GO:0031528; GO:0071914 39140 XM_044309335.1 0 1 3 0 22 NA NA NA NA NA NA 39141 XM_029325668.2 2073 2208 1586 2079 1605 Q96C24 4.19e-58 Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin) Homo sapiens (Human) exocytosis [GO:0006887]; insulin secretion [GO:0030073]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; multivesicular body sorting pathway [GO:0071985]; negative regulation of insulin secretion [GO:0046676]; plasma membrane repair [GO:0001778]; positive regulation of exocytosis [GO:0045921]; positive regulation of protein secretion [GO:0050714]; regulation of plasma membrane repair [GO:1905684] GO:0001778; GO:0005543; GO:0005768; GO:0005886; GO:0006886; GO:0006887; GO:0019898; GO:0030073; GO:0030658; GO:0031092; GO:0031267; GO:0032418; GO:0042043; GO:0045921; GO:0046676; GO:0046872; GO:0050714; GO:0070382; GO:0071985; GO:1905684 39142 XM_029325668.2 2073 2208 1586 2079 1605 Q96C24 2.47e-26 Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin) Homo sapiens (Human) exocytosis [GO:0006887]; insulin secretion [GO:0030073]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; multivesicular body sorting pathway [GO:0071985]; negative regulation of insulin secretion [GO:0046676]; plasma membrane repair [GO:0001778]; positive regulation of exocytosis [GO:0045921]; positive regulation of protein secretion [GO:0050714]; regulation of plasma membrane repair [GO:1905684] GO:0001778; GO:0005543; GO:0005768; GO:0005886; GO:0006886; GO:0006887; GO:0019898; GO:0030073; GO:0030658; GO:0031092; GO:0031267; GO:0032418; GO:0042043; GO:0045921; GO:0046676; GO:0046872; GO:0050714; GO:0070382; GO:0071985; GO:1905684 39143 XM_044325666.1 0 33 0 0 0 NA NA NA NA NA NA 39144 XM_044327633.1 25 4 2 23 58 NA NA NA NA NA NA 39145 XM_044311380.1 0 4 0 9 10 Q95LR0 1.93e-85 Cilia- and flagella-associated protein 91 (CFAP91) (AMY-1-associating protein expressed in testis 1) (AAT-1) (MYCBP/AMY-1-associated testis-expressed protein 1) (Protein MAATS1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) axonemal central apparatus assembly [GO:1904158]; cell differentiation [GO:0030154]; cilium movement [GO:0003341]; spermatogenesis [GO:0007283] GO:0003341; GO:0005739; GO:0005930; GO:0007283; GO:0030154; GO:0031514; GO:1904158 39146 XM_044323518.1 1 0 0 2 47 NA NA NA NA NA NA 39147 XM_044329014.1 456 167 236 221 120 NA NA NA NA NA NA 39148 XM_029336584.2 13 24 12 9 44 NA NA NA NA NA NA 39149 XM_029358554.2 87 25 17 60 41 Q17QQ2 6.35e-36 Thiopurine S-methyltransferase (EC 2.1.1.67) (Thiopurine methyltransferase) Bos taurus (Bovine) methylation [GO:0032259]; xenobiotic metabolic process [GO:0006805] GO:0005737; GO:0006805; GO:0008119; GO:0032259; GO:1904047 39150 XM_029348857.2 493 309 134 330 32 O75081 3.63e-131 Protein CBFA2T3 (MTG8-related protein 2) (Myeloid translocation gene on chromosome 16 protein) (hMTG16) (Zinc finger MYND domain-containing protein 4) Homo sapiens (Human) granulocyte differentiation [GO:0030851]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of glycolytic process [GO:0045820]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; regulation of aerobic respiration [GO:1903715]; response to hypoxia [GO:0001666] GO:0000139; GO:0001666; GO:0003714; GO:0005634; GO:0005654; GO:0005730; GO:0008285; GO:0030851; GO:0032436; GO:0045820; GO:0045892; GO:0046872; GO:1903715 39151 XM_029334482.2 1493 566 506 1167 613 Q9VZF4 1.09e-23 F-box/WD repeat-containing protein 7 (F-box and WD-40 domain-containing protein 7) (Protein archipelago) Drosophila melanogaster (Fruit fly) branch fusion, open tracheal system [GO:0035147]; cellular response to hypoxia [GO:0071456]; DNA endoreduplication [GO:0042023]; negative regulation of cellular response to hypoxia [GO:1900038]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of growth [GO:0045926]; negative regulation of imaginal disc growth [GO:0045571]; protein ubiquitination [GO:0016567]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of exit from mitosis [GO:0007096]; regulation of mitotic nuclear division [GO:0007088]; regulation of proteolysis [GO:0030162]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; trachea development [GO:0060438]; ventral cord development [GO:0007419] GO:0005634; GO:0007088; GO:0007096; GO:0007419; GO:0016567; GO:0019005; GO:0030162; GO:0030332; GO:0031146; GO:0035147; GO:0042023; GO:0045571; GO:0045926; GO:0060253; GO:0060438; GO:0071456; GO:1900038; GO:1903146; GO:1990381 39152 XM_044327291.1 1080 1046 480 1297 670 NA NA NA NA NA NA 39153 XM_029339651.2 537 240 298 378 709 A4IG62 4.89e-177 ATP-dependent RNA helicase SUPV3L1, mitochondrial (EC 3.6.4.13) (Suppressor of var1 3-like protein 1) (SUV3-like protein 1) Danio rerio (Zebrafish) (Brachydanio rerio) DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; liver development [GO:0001889]; mitochondrial mRNA catabolic process [GO:0000958]; mitochondrial mRNA surveillance [GO:0035946]; mitochondrial ncRNA surveillance [GO:0035945]; mitochondrial RNA 3'-end processing [GO:0000965]; mitochondrial RNA surveillance [GO:2000827]; mitochondrion morphogenesis [GO:0070584]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell growth [GO:0030307]; positive regulation of mitochondrial RNA catabolic process [GO:0000962]; RNA catabolic process [GO:0006401] GO:0000958; GO:0000962; GO:0000965; GO:0001889; GO:0003677; GO:0003678; GO:0003724; GO:0003725; GO:0005524; GO:0005634; GO:0005739; GO:0005759; GO:0006310; GO:0006401; GO:0016887; GO:0030307; GO:0032508; GO:0034458; GO:0035945; GO:0035946; GO:0042645; GO:0043066; GO:0045025; GO:0070584; GO:2000827 39154 XM_044309627.1 0 3 18 9 4 NA NA NA NA NA NA 39155 XM_029332046.2 143 5 106 129 148 Q8JIR0 6.16e-57 Polycomb complex protein BMI-1-A (Polycomb group RING finger protein 4-A) Danio rerio (Zebrafish) (Brachydanio rerio) cerebellum development [GO:0021549]; hematopoietic stem cell migration [GO:0035701]; histone H2A-K119 monoubiquitination [GO:0036353]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of transcription by RNA polymerase II [GO:0000122]; primitive hemopoiesis [GO:0060215] GO:0000122; GO:0021549; GO:0031519; GO:0035102; GO:0035701; GO:0036353; GO:0045814; GO:0046872; GO:0060215; GO:1990841 39156 XM_044314235.1 3051 2440 1086 3046 2643 P04636 3.98e-150 Malate dehydrogenase, mitochondrial (EC 1.1.1.37) Rattus norvegicus (Rat) aerobic respiration [GO:0009060]; gluconeogenesis [GO:0006094]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099] GO:0005737; GO:0005739; GO:0005759; GO:0006094; GO:0006099; GO:0006107; GO:0006108; GO:0006734; GO:0009060; GO:0016020; GO:0016615; GO:0030060; GO:0042803; GO:0043621; GO:0046554 39157 XM_044329060.1 16 20 16 16 11 NA NA NA NA NA NA 39158 XR_006391347.1 9 0 12 4 18 Q9U6Y6 2.07e-107 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 39159 XM_044328354.1 536 502 311 444 434 B4JDU5 1.46e-127 KRR1 small subunit processome component homolog (KRR-R motif-containing protein 1) (Protein dribble) Drosophila grimshawi (Hawaiian fruit fly) (Idiomyia grimshawi) rRNA processing [GO:0006364] GO:0003677; GO:0003723; GO:0005654; GO:0005730; GO:0006364; GO:1990904 39160 XR_003825177.2 19 33 15 16 16 NA NA NA NA NA NA 39161 XM_029333473.2 4 5 22 14 0 NA NA NA NA NA NA 39162 XM_044313920.1 0 0 0 16 0 NA NA NA NA NA NA 39163 XM_044324370.1 64 9 70 6 19 NA NA NA NA NA NA 39164 XR_006392570.1 39 14 16 16 18 Q9ULL4 4.14e-45 Plexin-B3 Homo sapiens (Human) cell chemotaxis [GO:0060326]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell migration [GO:0030336]; negative regulation of GTPase activity [GO:0034260]; negative regulation of lamellipodium assembly [GO:0010593]; positive chemotaxis [GO:0050918]; positive regulation of axonogenesis [GO:0050772]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neuron projection development [GO:0010976]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287] GO:0001938; GO:0002116; GO:0005886; GO:0007156; GO:0007162; GO:0008360; GO:0009986; GO:0010593; GO:0010976; GO:0017154; GO:0019904; GO:0030334; GO:0030336; GO:0034260; GO:0043087; GO:0050772; GO:0050918; GO:0051022; GO:0060326; GO:0071526; GO:0098632; GO:1902287 39165 XR_006392570.1 39 14 16 16 18 Q9ULL4 4.14e-45 Plexin-B3 Homo sapiens (Human) cell chemotaxis [GO:0060326]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell migration [GO:0030336]; negative regulation of GTPase activity [GO:0034260]; negative regulation of lamellipodium assembly [GO:0010593]; positive chemotaxis [GO:0050918]; positive regulation of axonogenesis [GO:0050772]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neuron projection development [GO:0010976]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287] GO:0001938; GO:0002116; GO:0005886; GO:0007156; GO:0007162; GO:0008360; GO:0009986; GO:0010593; GO:0010976; GO:0017154; GO:0019904; GO:0030334; GO:0030336; GO:0034260; GO:0043087; GO:0050772; GO:0050918; GO:0051022; GO:0060326; GO:0071526; GO:0098632; GO:1902287 39166 XR_006392570.1 39 14 16 16 18 Q9ULL4 4.14e-45 Plexin-B3 Homo sapiens (Human) cell chemotaxis [GO:0060326]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell migration [GO:0030336]; negative regulation of GTPase activity [GO:0034260]; negative regulation of lamellipodium assembly [GO:0010593]; positive chemotaxis [GO:0050918]; positive regulation of axonogenesis [GO:0050772]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neuron projection development [GO:0010976]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287] GO:0001938; GO:0002116; GO:0005886; GO:0007156; GO:0007162; GO:0008360; GO:0009986; GO:0010593; GO:0010976; GO:0017154; GO:0019904; GO:0030334; GO:0030336; GO:0034260; GO:0043087; GO:0050772; GO:0050918; GO:0051022; GO:0060326; GO:0071526; GO:0098632; GO:1902287 39167 XR_003827025.2 38 57 25 31 31 NA NA NA NA NA NA 39168 XM_044327259.1 33 22 15 56 40 Q96AY4 1.66e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 39169 XM_044327259.1 33 22 15 56 40 Q96AY4 3.3e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 39170 XM_044327259.1 33 22 15 56 40 Q96AY4 1.04e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 39171 XM_044327259.1 33 22 15 56 40 Q96AY4 1.04e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 39172 XM_044327259.1 33 22 15 56 40 Q96AY4 3.34e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 39173 XM_044327259.1 33 22 15 56 40 Q96AY4 3.34e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 39174 XM_029349218.2 1118 392 326 358 236 Q16RX1 3.83e-32 Mediator of RNA polymerase II transcription subunit 21 (Mediator complex subunit 21) Aedes aegypti (Yellowfever mosquito) (Culex aegypti) regulation of DNA-templated transcription [GO:0006355] GO:0006355; GO:0016592 39175 XM_029339877.2 30061 39810 20614 23584 14848 O76756 2.07e-105 40S ribosomal protein S8 Apis mellifera (Honeybee) translation [GO:0006412] GO:0003735; GO:0005840; GO:0006412; GO:1990904 39176 XM_029337575.2 8 14 15 5 12 P28575 9.22e-34 Actin-binding protein IPP (Intracisternal A particle-promoted polypeptide) (IPP) (Murine IAP-promoted placenta-expressed protein) (Protein MIPP) Mus musculus (Mouse) NA GO:0003779; GO:0005737; GO:0005856 39177 XM_044307209.1 631 353 253 400 528 D3ZSC8 2.01e-65 DnaJ homolog subfamily C member 17 Rattus norvegicus (Rat) negative regulation of transcription by RNA polymerase II [GO:0000122]; spliceosomal complex disassembly [GO:0000390]; toxin transport [GO:1901998] GO:0000122; GO:0000390; GO:0003723; GO:0005634; GO:0005681; GO:0005737; GO:1901998 39178 XR_003826101.2 17 20 18 19 61 NA NA NA NA NA NA 39179 XR_003827517.2 184 245 214 195 62 NA NA NA NA NA NA 39180 XM_029334858.2 0 14 8 0 22 NA NA NA NA NA NA 39181 XM_044323750.1 18 0 0 0 3 NA NA NA NA NA NA 39182 XM_029329413.2 214 76 119 142 175 Q09143 6.61e-115 High affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (Ecotropic retroviral leukemia receptor) (Ecotropic retrovirus receptor) (ERR) (EcoR) (Solute carrier family 7 member 1) (System Y+ basic amino acid transporter) Mus musculus (Mouse) amino acid import across plasma membrane [GO:0089718]; amino acid transport [GO:0006865]; L-amino acid transport [GO:0015807]; L-arginine import across plasma membrane [GO:0097638]; L-arginine transmembrane transport [GO:1903826]; L-histidine import across plasma membrane [GO:1903810]; L-ornithine transmembrane transport [GO:1903352]; lysine transport [GO:0015819]; ornithine transport [GO:0015822]; positive regulation of T cell proliferation [GO:0042102]; regulation of TOR signaling [GO:0032006] GO:0000064; GO:0001618; GO:0005290; GO:0005886; GO:0006865; GO:0009925; GO:0015171; GO:0015174; GO:0015189; GO:0015807; GO:0015819; GO:0015822; GO:0016020; GO:0016323; GO:0016324; GO:0032006; GO:0032991; GO:0042102; GO:0061459; GO:0089718; GO:0097638; GO:1903352; GO:1903810; GO:1903826 39183 XM_044310045.1 0 0 0 0 46 Q28824 7.01e-75 Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form] Bos taurus (Bovine) protein phosphorylation [GO:0006468]; tonic smooth muscle contraction [GO:0014820] GO:0001725; GO:0003779; GO:0004672; GO:0004687; GO:0005516; GO:0005524; GO:0005737; GO:0006468; GO:0014820; GO:0030027; GO:0032154; GO:0046872 39184 XM_029328997.2 825 461 269 253 457 Q8N543 3.29e-151 Prolyl 3-hydroxylase OGFOD1 (EC 1.14.11.-) (2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1) (Termination and polyadenylation 1 homolog) (uS12 prolyl 3-hydroxylase) Homo sapiens (Human) cell population proliferation [GO:0008283]; peptidyl-proline hydroxylation [GO:0019511]; protein hydroxylation [GO:0018126]; regulation of translational termination [GO:0006449]; stress granule assembly [GO:0034063] GO:0005506; GO:0005654; GO:0005737; GO:0005829; GO:0006449; GO:0008283; GO:0010494; GO:0018126; GO:0019511; GO:0031418; GO:0031543; GO:0031544; GO:0034063 39185 XM_044317321.1 239 68 110 3 7 O16025 8.61e-35 Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (AOS) (EC 4.2.1.-) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)] Plexaura homomalla (Black sea rod) arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; lipid oxidation [GO:0034440]; oxylipin biosynthetic process [GO:0031408] GO:0005506; GO:0005737; GO:0006633; GO:0009978; GO:0016020; GO:0019369; GO:0020037; GO:0031408; GO:0034440; GO:0047677 39186 XM_044318302.1 103 226 13 188 205 Q96CG8 4.76e-44 Collagen triple helix repeat-containing protein 1 Homo sapiens (Human) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005576; GO:0005581; GO:0005615; GO:0016477; GO:0016528; GO:0017147; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0062023; GO:0090090; GO:0090103; GO:0090177 39187 XM_044318302.1 103 226 13 188 205 Q96CG8 3.45e-42 Collagen triple helix repeat-containing protein 1 Homo sapiens (Human) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005576; GO:0005581; GO:0005615; GO:0016477; GO:0016528; GO:0017147; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0062023; GO:0090090; GO:0090103; GO:0090177 39188 XM_029332271.2 0 133 0 114 0 A5A779 3.24e-148 Geranylgeranyl transferase type-2 subunit alpha (EC 2.5.1.60) (Geranylgeranyl transferase type II subunit alpha) (Rab geranyl-geranyltransferase subunit alpha) (Rab GG transferase alpha) (Rab GGTase alpha) (Rab geranylgeranyltransferase subunit alpha) Sus scrofa (Pig) protein geranylgeranylation [GO:0018344] GO:0004663; GO:0005737; GO:0005968; GO:0008270; GO:0018344; GO:0031267 39189 XM_044326755.1 1 0 0 0 11 NA NA NA NA NA NA 39190 XM_044323233.1 80 56 144 0 0 Q9UNS1 2.82e-175 Protein timeless homolog (hTIM) Homo sapiens (Human) branching morphogenesis of an epithelial tube [GO:0048754]; cell cycle phase transition [GO:0044770]; cell division [GO:0051301]; cellular response to bleomycin [GO:1904976]; cellular response to cisplatin [GO:0072719]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hydroxyurea [GO:0072711]; circadian rhythm [GO:0007623]; detection of abiotic stimulus [GO:0009582]; DNA repair [GO:0006281]; DNA replication checkpoint signaling [GO:0000076]; lung development [GO:0030324]; morphogenesis of an epithelium [GO:0002009]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; regulation of circadian rhythm [GO:0042752]; replication fork arrest [GO:0043111]; replication fork protection [GO:0048478] GO:0000076; GO:0000785; GO:0002009; GO:0003677; GO:0005634; GO:0005654; GO:0006281; GO:0006974; GO:0007623; GO:0009582; GO:0030324; GO:0031298; GO:0035861; GO:0042752; GO:0042802; GO:0043111; GO:0044770; GO:0045892; GO:0048478; GO:0048754; GO:0051301; GO:0072711; GO:0072719; GO:1904976; GO:1905168; GO:2000781 39191 XM_029354889.2 509 877 612 765 395 NA NA NA NA NA NA 39192 XM_044325051.1 0 3 0 10 9 NA NA NA NA NA NA 39193 XM_029344258.2 3031 2281 1809 3017 2330 Q6AZN6 0 Phosphatidylinositol 3-kinase catalytic subunit type 3 (PI3-kinase type 3) (PI3K type 3) (PtdIns-3-kinase type 3) (EC 2.7.1.137) (Phosphoinositide-3-kinase class 3) Xenopus laevis (African clawed frog) autophagy [GO:0006914]; cell cycle [GO:0007049]; cell division [GO:0051301]; phosphatidylinositol-mediated signaling [GO:0048015]; phosphorylation [GO:0016310]; regulation of cytokinesis [GO:0032465] GO:0005524; GO:0006914; GO:0007049; GO:0016303; GO:0016310; GO:0030496; GO:0032465; GO:0048015; GO:0051301 39194 XM_044326154.1 29 11 72 23 62 NA NA NA NA NA NA 39195 XM_044323463.1 8 4 358 1456 18 NA NA NA NA NA NA 39196 XM_044328334.1 0 0 0 239 46 B3CQD1 1.66e-115 Peptide chain release factor 1 (RF-1) Orientia tsutsugamushi (strain Ikeda) (Rickettsia tsutsugamushi) NA GO:0005737; GO:0016149 39197 XM_044311952.1 259 8 12 9 80 NA NA NA NA NA NA 39198 XM_044328009.1 557 169 478 410 493 Q80ZA4 0 Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86) Mus musculus (Mouse) sensory perception of sound [GO:0007605] GO:0007605; GO:0016020; GO:0032426; GO:0120234 39199 XM_044306908.1 0 57 0 23 0 NA NA NA NA NA NA 39200 XR_006393215.1 137 68 11 179 65 NA NA NA NA NA NA 39201 XM_044328041.1 74 17 77 63 108 Q7TN88 1.64e-78 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 39202 XM_044328041.1 74 17 77 63 108 Q7TN88 4.83e-73 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 39203 XR_006397986.1 0 3 8 2 2 NA NA NA NA NA NA 39204 XR_006397770.1 294 71 98 23 85 NA NA NA NA NA NA 39205 XM_044326707.1 60 34 42 53 44 NA NA NA NA NA NA 39206 XM_029338736.2 25 18 0 11 19 Q9BVH7 7.48e-24 Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 (EC 2.4.99.-) (GD1 alpha synthase) (GalNAc alpha-2,6-sialyltransferase V) (ST6GalNAc V) (ST6GalNAcV) (Sialyltransferase 7E) (SIAT7-E) Homo sapiens (Human) ganglioside biosynthetic process [GO:0001574]; glycosphingolipid biosynthetic process [GO:0006688]; oligosaccharide biosynthetic process [GO:0009312]; oligosaccharide metabolic process [GO:0009311]; protein glycosylation [GO:0006486] GO:0000139; GO:0001574; GO:0001665; GO:0006486; GO:0006688; GO:0008373; GO:0009311; GO:0009312 39207 XM_044315267.1 8 0 0 4 0 NA NA NA NA NA NA 39208 XM_044317059.1 0 32 0 55 0 NA NA NA NA NA NA 39209 XM_044322618.1 481 393 287 407 354 Q6AZW2 3.73e-91 Aldo-keto reductase family 1 member A1-A (Alcohol dehydrogenase [NADP(+)] A) (EC 1.1.1.2) (Aldehyde reductase-A) Danio rerio (Zebrafish) (Brachydanio rerio) aldehyde catabolic process [GO:0046185]; cellular detoxification of aldehyde [GO:0110095] GO:0004032; GO:0005829; GO:0016324; GO:0046185; GO:0110095 39210 XM_029357717.2 0 0 49 0 0 NA NA NA NA NA NA 39211 XM_029346576.2 1319 886 750 895 866 NA NA NA NA NA NA 39212 XR_003823868.2 0 0 3 26 13 NA NA NA NA NA NA 39213 XM_029332638.2 14984 12865 5861 7311 3098 P26632 1.18e-51 Early growth response protein 1 (EGR-1) (Zinc finger protein Krox-24) Danio rerio (Zebrafish) (Brachydanio rerio) camera-type eye development [GO:0043010]; circadian regulation of gene expression [GO:0032922]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; embryonic viscerocranium morphogenesis [GO:0048703]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005737; GO:0006357; GO:0008270; GO:0010385; GO:0032922; GO:0043010; GO:0043565; GO:0044729; GO:0045893; GO:0045944; GO:0048703; GO:0060059; GO:1990841 39214 XM_029330818.2 3188 2569 1776 3045 3062 Q21305 3.07e-30 Transcription factor sox-2 Caenorhabditis elegans anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; neuron fate specification [GO:0048665]; regulation of DNA-templated transcription [GO:0006355] GO:0000977; GO:0000978; GO:0000981; GO:0005634; GO:0006355; GO:0009653; GO:0030154; GO:0048665 39215 XM_044308341.1 455 124 165 246 371 NA NA NA NA NA NA 39216 XM_029337005.2 121 160 177 353 199 O95685 3.4e-24 Protein phosphatase 1 regulatory subunit 3D (Protein phosphatase 1 regulatory subunit 6) (PP1 subunit R6) (Protein phosphatase 1-binding subunit R6) Homo sapiens (Human) glycogen metabolic process [GO:0005977]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of glycogen catabolic process [GO:0005981] GO:0000164; GO:0004722; GO:0005977; GO:0005979; GO:0005981; GO:0008157; GO:0042587; GO:0043231; GO:2001069 39217 XM_029346309.2 1076 170 374 281 816 Q6L8S8 1.35e-59 Beta-1,4-N-acetylgalactosaminyltransferase 3 (Beta4GalNAc-T3) (Beta4GalNAcT3) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase III) (N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 2) (NGalNAc-T2) Mus musculus (Mouse) chondroitin sulfate biosynthetic process [GO:0030206] GO:0005794; GO:0008376; GO:0030206; GO:0032580; GO:0033842; GO:0043231; GO:0047238 39218 XM_029336082.2 0 20 0 1 43 Q90867 6.55e-77 Hepatocyte nuclear factor 1-alpha (HNF-1-alpha) (HNF-1A) (Transcription factor 1) (TCF-1) Gallus gallus (Chicken) glucose homeostasis [GO:0042593]; insulin secretion [GO:0030073]; liver development [GO:0001889]; pancreas development [GO:0031016]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000976; GO:0000978; GO:0000981; GO:0001889; GO:0003700; GO:0005634; GO:0006357; GO:0030073; GO:0031016; GO:0032991; GO:0042593; GO:0045893 39219 XM_044311933.1 74 44 60 44 137 NA NA NA NA NA NA 39220 XM_029351059.2 284 132 146 230 618 NA NA NA NA NA NA 39221 XM_044319428.1 5 5 4 1 6 NA NA NA NA NA NA 39222 XM_029326908.2 274 199 209 235 400 Q3UMC0 0 Ribosome biogenesis protein SPATA5 (EC 3.6.4.10) (Spermatogenesis-associated factor protein) (Spermatogenesis-associated protein 5) Mus musculus (Mouse) brain development [GO:0007420]; cell differentiation [GO:0030154]; ribosomal large subunit biogenesis [GO:0042273]; spermatogenesis [GO:0007283] GO:0005524; GO:0005737; GO:0005739; GO:0005819; GO:0007283; GO:0007420; GO:0016887; GO:0030154; GO:0042273; GO:1990275 39223 XM_044319240.1 1514 786 851 1236 1266 Q14703 0 Membrane-bound transcription factor site-1 protease (EC 3.4.21.112) (Endopeptidase S1P) (Subtilisin/kexin-isozyme 1) (SKI-1) Homo sapiens (Human) ATF6-mediated unfolded protein response [GO:0036500]; cholesterol metabolic process [GO:0008203]; endoplasmic reticulum unfolded protein response [GO:0030968]; lysosome organization [GO:0007040]; membrane protein intracellular domain proteolysis [GO:0031293]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of vesicle-mediated transport [GO:0060627]; response to endoplasmic reticulum stress [GO:0034976] GO:0000139; GO:0004252; GO:0005788; GO:0005789; GO:0005794; GO:0005795; GO:0006508; GO:0007040; GO:0008203; GO:0016485; GO:0030968; GO:0031293; GO:0034976; GO:0036500; GO:0045540; GO:0060627 39224 XM_029335019.2 291 135 144 348 385 Q84K35 4.8e-106 Pseudouridine-5'-phosphate glycosidase (PsiMP glycosidase) (EC 4.2.1.70) (Pseudouridine monophosphate glycosidase) Arabidopsis thaliana (Mouse-ear cress) NA GO:0004730; GO:0005777; GO:0030597; GO:0046872 39225 XM_029324459.2 0 15 0 6 12 NA NA NA NA NA NA 39226 XM_044323872.1 47 8 17 1 49 NA NA NA NA NA NA 39227 XM_044307017.1 138 111 41 83 146 Q7RTR2 1.31e-56 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 39228 XM_044307017.1 138 111 41 83 146 Q7RTR2 1.33e-55 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 39229 XM_044307017.1 138 111 41 83 146 Q7RTR2 1.24e-43 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 39230 XM_044307017.1 138 111 41 83 146 Q7RTR2 1.98e-36 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 39231 XM_044307017.1 138 111 41 83 146 Q7RTR2 7.62e-29 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 39232 XM_029335016.2 2000 1602 1324 2492 2074 Q5RHP9 1.44e-32 Glutamate-rich protein 3 Homo sapiens (Human) NA NA 39233 XM_029335016.2 2000 1602 1324 2492 2074 Q5RHP9 3.39e-31 Glutamate-rich protein 3 Homo sapiens (Human) NA NA 39234 XM_029349347.2 67 11 0 5 32 A7RX34 2.56e-76 THO complex subunit 7 homolog Nematostella vectensis (Starlet sea anemone) mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397] GO:0000445; GO:0005737; GO:0006397; GO:0006406; GO:0016607 39235 XM_029353817.2 577 309 0 6368 6791 Q32LP4 0 Sodium-driven chloride bicarbonate exchanger (Solute carrier family 4 member 10) Bos taurus (Bovine) bicarbonate transport [GO:0015701]; brain morphogenesis [GO:0048854]; ion homeostasis [GO:0050801]; locomotory exploration behavior [GO:0035641]; multicellular organism growth [GO:0035264]; post-embryonic development [GO:0009791]; proton transmembrane transport [GO:1902600]; pyramidal neuron development [GO:0021860]; regulation of intracellular pH [GO:0051453]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; response to light stimulus [GO:0009416]; transmembrane transport [GO:0055085]; visual perception [GO:0007601] GO:0005886; GO:0007601; GO:0008510; GO:0009416; GO:0009791; GO:0015701; GO:0016323; GO:0016324; GO:0021860; GO:0022857; GO:0030425; GO:0035264; GO:0035641; GO:0036477; GO:0043025; GO:0043204; GO:0043679; GO:0045202; GO:0048172; GO:0048854; GO:0050801; GO:0051453; GO:0055085; GO:0097440; GO:0097441; GO:0097442; GO:0098794; GO:0140892; GO:1902600 39236 XM_044313243.1 977 251 366 952 801 Q5VV63 1.27e-124 Attractin-like protein 1 Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; G protein-coupled receptor signaling pathway [GO:0007186]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888] GO:0005604; GO:0007186; GO:0009887; GO:0009888; GO:0016020; GO:0016477; GO:0030246; GO:0034446 39237 XM_044313243.1 977 251 366 952 801 Q5VV63 1.77e-83 Attractin-like protein 1 Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; G protein-coupled receptor signaling pathway [GO:0007186]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888] GO:0005604; GO:0007186; GO:0009887; GO:0009888; GO:0016020; GO:0016477; GO:0030246; GO:0034446 39238 XM_029352048.2 1524 2166 1069 2880 1995 NA NA NA NA NA NA 39239 XR_006394130.1 0 3 16 20 11 NA NA NA NA NA NA 39240 XM_029335264.2 1195 993 846 1235 959 Q61235 1.33e-147 Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin-3) (SNT3) (Syntrophin-like) (SNTL) Mus musculus (Mouse) NA GO:0003779; GO:0005198; GO:0005516; GO:0005654; GO:0005737; GO:0005794; GO:0005874; GO:0005886; GO:0016010; GO:0030658; GO:0032991; GO:0045202; GO:0070161 39241 XM_044307498.1 33 78 48 61 107 NA NA NA NA NA NA 39242 XR_006392453.1 0 35 9 29 17 NA NA NA NA NA NA 39243 XR_006396286.1 404 161 170 285 401 Q5DW34 1.08e-131 Histone-lysine N-methyltransferase EHMT1 (EC 2.1.1.-) (EC 2.1.1.367) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a-like protein 1) (GLP) (GLP1) (Lysine N-methyltransferase 1D) Mus musculus (Mouse) chromatin organization [GO:0006325]; DNA methylation [GO:0006306]; facultative heterochromatin formation [GO:0140718]; histone H3-K9 methylation [GO:0051567]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-lysine dimethylation [GO:0018027]; peptidyl-lysine monomethylation [GO:0018026]; positive regulation of cold-induced thermogenesis [GO:0120162]; regulation of embryonic development [GO:0045995]; regulation of histone H3-K9 methylation [GO:0051570] GO:0000122; GO:0000785; GO:0001222; GO:0002039; GO:0005634; GO:0005654; GO:0006306; GO:0006325; GO:0008168; GO:0008270; GO:0016279; GO:0016604; GO:0018024; GO:0018026; GO:0018027; GO:0045892; GO:0045995; GO:0046974; GO:0046976; GO:0051567; GO:0051570; GO:0070742; GO:0120162; GO:0140718; GO:0140947 39244 XR_006396286.1 404 161 170 285 401 Q5DW34 1.08e-131 Histone-lysine N-methyltransferase EHMT1 (EC 2.1.1.-) (EC 2.1.1.367) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a-like protein 1) (GLP) (GLP1) (Lysine N-methyltransferase 1D) Mus musculus (Mouse) chromatin organization [GO:0006325]; DNA methylation [GO:0006306]; facultative heterochromatin formation [GO:0140718]; histone H3-K9 methylation [GO:0051567]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-lysine dimethylation [GO:0018027]; peptidyl-lysine monomethylation [GO:0018026]; positive regulation of cold-induced thermogenesis [GO:0120162]; regulation of embryonic development [GO:0045995]; regulation of histone H3-K9 methylation [GO:0051570] GO:0000122; GO:0000785; GO:0001222; GO:0002039; GO:0005634; GO:0005654; GO:0006306; GO:0006325; GO:0008168; GO:0008270; GO:0016279; GO:0016604; GO:0018024; GO:0018026; GO:0018027; GO:0045892; GO:0045995; GO:0046974; GO:0046976; GO:0051567; GO:0051570; GO:0070742; GO:0120162; GO:0140718; GO:0140947 39245 XR_003824705.2 844 4677 303 4078 365 NA NA NA NA NA NA 39246 XM_029357587.2 800 722 539 702 935 Q9QZB9 1.06e-107 Dynactin subunit 5 (Dynactin subunit p25) Mus musculus (Mouse) aorta development [GO:0035904]; coronary vasculature development [GO:0060976]; ventricular septum development [GO:0003281] GO:0000776; GO:0003281; GO:0005654; GO:0005737; GO:0005813; GO:0005869; GO:0031965; GO:0035904; GO:0060976 39247 XM_029339275.2 0 42 0 0 0 NA NA NA NA NA NA 39248 XM_029333236.2 2056 2002 1011 1420 2090 A6H757 2.56e-62 Lysophosphatidic acid phosphatase type 6 (EC 3.1.3.2) Bos taurus (Bovine) dephosphorylation [GO:0016311]; lysobisphosphatidic acid metabolic process [GO:2001311] GO:0003993; GO:0005739; GO:0016311; GO:0016791; GO:0052642; GO:2001311 39249 XR_006397214.1 832 451 726 914 1150 NA NA NA NA NA NA 39250 XM_029356229.2 0 0 108 0 640 O08528 5.21e-111 Hexokinase-2 (EC 2.7.1.1) (Hexokinase type II) (HK II) Mus musculus (Mouse) apoptotic mitochondrial changes [GO:0008637]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; cellular response to leukemia inhibitory factor [GO:1990830]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]; lactation [GO:0007595]; maintenance of protein location in mitochondrion [GO:0072656]; negative regulation of mitochondrial membrane permeability [GO:0035795]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; positive regulation of angiogenesis [GO:0045766]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; regulation of glucose import [GO:0046324]; response to hypoxia [GO:0001666]; response to ischemia [GO:0002931] GO:0001666; GO:0001678; GO:0002931; GO:0004340; GO:0004396; GO:0005524; GO:0005536; GO:0005739; GO:0005741; GO:0005813; GO:0005829; GO:0005886; GO:0006002; GO:0006006; GO:0006096; GO:0007595; GO:0008637; GO:0008865; GO:0016529; GO:0035795; GO:0043231; GO:0045766; GO:0046324; GO:0046835; GO:0051156; GO:0072655; GO:0072656; GO:1904925; GO:1990830; GO:2000378 39251 XM_029356229.2 0 0 108 0 640 O08528 1.11e-107 Hexokinase-2 (EC 2.7.1.1) (Hexokinase type II) (HK II) Mus musculus (Mouse) apoptotic mitochondrial changes [GO:0008637]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; cellular response to leukemia inhibitory factor [GO:1990830]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]; lactation [GO:0007595]; maintenance of protein location in mitochondrion [GO:0072656]; negative regulation of mitochondrial membrane permeability [GO:0035795]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; positive regulation of angiogenesis [GO:0045766]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; regulation of glucose import [GO:0046324]; response to hypoxia [GO:0001666]; response to ischemia [GO:0002931] GO:0001666; GO:0001678; GO:0002931; GO:0004340; GO:0004396; GO:0005524; GO:0005536; GO:0005739; GO:0005741; GO:0005813; GO:0005829; GO:0005886; GO:0006002; GO:0006006; GO:0006096; GO:0007595; GO:0008637; GO:0008865; GO:0016529; GO:0035795; GO:0043231; GO:0045766; GO:0046324; GO:0046835; GO:0051156; GO:0072655; GO:0072656; GO:1904925; GO:1990830; GO:2000378 39252 XM_029337802.2 346 580 254 486 580 Q499R4 1.36e-61 Threonylcarbamoyl-AMP synthase (EC 2.7.7.87) Rattus norvegicus (Rat) negative regulation of transport [GO:0051051]; regulation of translational fidelity [GO:0006450]; tRNA threonylcarbamoyladenosine modification [GO:0002949] GO:0000049; GO:0002949; GO:0003725; GO:0005737; GO:0005739; GO:0005886; GO:0006450; GO:0016020; GO:0016779; GO:0051051; GO:0061710 39253 XM_044314530.1 2 3 0 11 26 NA NA NA NA NA NA 39254 XM_029341340.2 0 0 0 0 14 NA NA NA NA NA NA 39255 XM_044315883.1 9 3 0 6 8 NA NA NA NA NA NA 39256 XM_044326242.1 498 616 393 513 371 NA NA NA NA NA NA 39257 XM_029352377.2 11 0 19 13 5 NA NA NA NA NA NA 39258 XM_029333373.2 1850 2818 208 2009 849 NA NA NA NA NA NA 39259 XM_044320429.1 0 0 20 0 9 NA NA NA NA NA NA 39260 XR_006391373.1 45 25 2 51 35 NA NA NA NA NA NA 39261 XM_029356937.2 113 123 100 152 153 P13439 2.96e-178 Uridine 5'-monophosphate synthase (UMP synthase) [Includes: Orotate phosphoribosyltransferase (OPRTase) (EC 2.4.2.10); Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23) (OMPdecase)] Mus musculus (Mouse) 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular response to xenobiotic stimulus [GO:0071466]; female pregnancy [GO:0007565]; lactation [GO:0007595]; pyrimidine nucleobase biosynthetic process [GO:0019856]; UDP biosynthetic process [GO:0006225]; UMP biosynthetic process [GO:0006222] GO:0004588; GO:0004590; GO:0005634; GO:0005737; GO:0006207; GO:0006222; GO:0006225; GO:0007565; GO:0007595; GO:0019856; GO:0042802; GO:0044205; GO:0071466 39262 XM_044325463.1 194 72 71 63 125 NA NA NA NA NA NA 39263 XR_006392530.1 0 0 0 10 4 NA NA NA NA NA NA 39264 XM_044313174.1 1602 930 873 1112 914 A7MFZ8 1.33e-28 Glyoxylate/hydroxypyruvate reductase A (EC 1.1.1.79) (EC 1.1.1.81) (2-ketoacid reductase) Cronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii) NA GO:0005737; GO:0005886; GO:0008465; GO:0016618; GO:0030267; GO:0051287 39265 XM_029358187.2 433 293 299 314 431 NA NA NA NA NA NA 39266 XM_044326451.1 89 0 0 172 48 NA NA NA NA NA NA 39267 XM_044323218.1 42 0 9 5 7 NA NA NA NA NA NA 39268 XM_029334756.2 812 390 217 176 307 C3VPR6 6.03e-23 Protein NLRC5 Mus musculus (Mouse) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of type II interferon-mediated signaling pathway [GO:0060335]; regulation of kinase activity [GO:0043549]; response to bacterium [GO:0009617] GO:0000978; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0009617; GO:0032088; GO:0035556; GO:0043549; GO:0045087; GO:0045345; GO:0045944; GO:0051607; GO:0060335; GO:0060339; GO:0060340 39269 XM_044322718.1 0 0 26 2 0 NA NA NA NA NA NA 39270 XM_029349520.2 17 8 0 0 0 NA NA NA NA NA NA 39271 XM_044309431.1 1 1 10 0 1 NA NA NA NA NA NA 39272 XM_029342023.2 208 206 171 239 398 Q4KLM5 6.24e-43 Activator of basal transcription 1 Rattus norvegicus (Rat) endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000480]; endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000447]; endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000472]; regulation of transcription by RNA polymerase II [GO:0006357]; small-subunit processome assembly [GO:0034462]; spinal cord motor neuron differentiation [GO:0021522] GO:0000447; GO:0000472; GO:0000480; GO:0003677; GO:0003723; GO:0005667; GO:0005730; GO:0006357; GO:0021522; GO:0034462 39273 XM_029343345.2 667 729 579 930 451 Q4U0T9 6.92e-32 Cysteine and glycine-rich protein 3 (Cysteine-rich protein 3) (CRP3) Bos taurus (Bovine) actin cytoskeleton organization [GO:0030036]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac myofibril assembly [GO:0055003]; cellular calcium ion homeostasis [GO:0006874]; detection of muscle stretch [GO:0035995]; glucose homeostasis [GO:0042593]; inflammatory response [GO:0006954]; insulin receptor signaling pathway [GO:0008286]; muscle cell cellular homeostasis [GO:0046716]; muscle organ development [GO:0007517]; muscle tissue development [GO:0060537]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein kinase C signaling [GO:0070528]; protein localization to organelle [GO:0033365]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of the force of heart contraction [GO:0002026]; sarcomere organization [GO:0045214]; T-tubule organization [GO:0033292] GO:0002026; GO:0003300; GO:0003779; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0006874; GO:0006954; GO:0007517; GO:0008286; GO:0008307; GO:0030018; GO:0030036; GO:0031433; GO:0033292; GO:0033365; GO:0035995; GO:0042593; GO:0042802; GO:0042805; GO:0045214; GO:0045944; GO:0046716; GO:0046872; GO:0055003; GO:0060048; GO:0060537; GO:0070528; GO:1903076 39274 XM_044307605.1 134 70 63 47 279 C9D7C2 0 Voltage-dependent calcium channel type A subunit alpha-1 (Cacophony protein) Apis mellifera (Honeybee) regulation of ion transmembrane transport [GO:0034765] GO:0005245; GO:0005509; GO:0005891; GO:0034765 39275 XM_044307605.1 134 70 63 47 279 C9D7C2 5e-164 Voltage-dependent calcium channel type A subunit alpha-1 (Cacophony protein) Apis mellifera (Honeybee) regulation of ion transmembrane transport [GO:0034765] GO:0005245; GO:0005509; GO:0005891; GO:0034765 39276 XM_044307605.1 134 70 63 47 279 C9D7C2 4.61e-33 Voltage-dependent calcium channel type A subunit alpha-1 (Cacophony protein) Apis mellifera (Honeybee) regulation of ion transmembrane transport [GO:0034765] GO:0005245; GO:0005509; GO:0005891; GO:0034765 39277 XM_044326488.1 43 2 38 14 107 P26714 3.57e-21 Gamma-aminobutyric acid receptor subunit beta (GABA(A) receptor) Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004890; GO:0005230; GO:0005254; GO:0034707; GO:0045211 39278 XM_029332586.2 870 465 427 765 640 B6CZ61 9.18e-47 Leucine-rich repeat-containing protein 51 Rattus norvegicus (Rat) NA GO:0005737 39279 XM_029328776.2 0 0 0 7 37 Q5XXP2 9.36e-29 Melanopsin (Opsin-4) Phodopus sungorus (Striped hairy-footed hamster) (Djungarian hamster) hyaloid vascular plexus regression [GO:1990384]; optokinetic behavior [GO:0007634]; phototransduction [GO:0007602]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511]; visual perception [GO:0007601] GO:0005502; GO:0005886; GO:0007601; GO:0007602; GO:0007634; GO:0008020; GO:0016020; GO:0030424; GO:0030425; GO:0042752; GO:0043204; GO:0048511; GO:1990384 39280 XM_029334715.2 35 0 103 0 190 Q66JY2 5.91e-39 INO80 complex subunit D Mus musculus (Mouse) chromatin remodeling [GO:0006338]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of telomere maintenance in response to DNA damage [GO:1904507]; regulation of cell cycle [GO:0051726]; regulation of chromosome organization [GO:0033044]; regulation of DNA repair [GO:0006282]; regulation of DNA replication [GO:0006275]; regulation of DNA strand elongation [GO:0060382]; regulation of embryonic development [GO:0045995]; telomere maintenance [GO:0000723] GO:0000723; GO:0005634; GO:0006275; GO:0006281; GO:0006282; GO:0006310; GO:0006338; GO:0031011; GO:0033044; GO:0045739; GO:0045893; GO:0045995; GO:0051726; GO:0060382; GO:1904507 39281 XR_003825246.2 1 0 0 79 5 NA NA NA NA NA NA 39282 XM_044311568.1 67 107 42 126 126 Q8C5P5 4.31e-79 5'-nucleotidase domain-containing protein 1 (EC 3.1.3.-) (Cytosolic 5'-nucleotidase II-like protein 1) Mus musculus (Mouse) NA GO:0008253; GO:0046872 39283 XM_044323632.1 7 0 0 0 0 NA NA NA NA NA NA 39284 XM_044319757.1 0 0 0 0 8 Q5BIM1 1.05e-52 Tripartite motif-containing protein 45 Bos taurus (Bovine) bone development [GO:0060348]; positive regulation of DNA-templated transcription [GO:0045893] GO:0000785; GO:0004842; GO:0005654; GO:0005829; GO:0008270; GO:0045171; GO:0045893; GO:0060348 39285 XM_044307123.1 238 138 149 195 191 NA NA NA NA NA NA 39286 XM_044320259.1 96 28 55 14 210 NA NA NA NA NA NA 39287 XM_044319237.1 4974 2202 2617 1477 2665 NA NA NA NA NA NA 39288 XM_029329033.2 819 908 558 1201 413 Q6DFF6 6.06e-165 Kelch-like protein 20 Xenopus laevis (African clawed frog) Golgi to endosome transport [GO:0006895]; negative regulation of apoptotic process [GO:0043066]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K33-linked ubiquitination [GO:1990390]; protein transport [GO:0015031]; protein ubiquitination [GO:0016567] GO:0004842; GO:0005737; GO:0005802; GO:0005829; GO:0006895; GO:0015031; GO:0016567; GO:0016605; GO:0019964; GO:0031463; GO:0043066; GO:0043161; GO:0048471; GO:1990390 39289 XM_029329033.2 819 908 558 1201 413 Q6DFF6 3.36e-23 Kelch-like protein 20 Xenopus laevis (African clawed frog) Golgi to endosome transport [GO:0006895]; negative regulation of apoptotic process [GO:0043066]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K33-linked ubiquitination [GO:1990390]; protein transport [GO:0015031]; protein ubiquitination [GO:0016567] GO:0004842; GO:0005737; GO:0005802; GO:0005829; GO:0006895; GO:0015031; GO:0016567; GO:0016605; GO:0019964; GO:0031463; GO:0043066; GO:0043161; GO:0048471; GO:1990390 39290 XM_029326932.2 522 448 339 545 453 Q66IL0 6.48e-120 Chitinase domain-containing protein 1 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) carbohydrate metabolic process [GO:0005975] GO:0005576; GO:0005764; GO:0005975; GO:0008061 39291 XM_044324117.1 12 37 36 8 23 NA NA NA NA NA NA 39292 XM_044317177.1 10 5 11 28 2 NA NA NA NA NA NA 39293 XM_029329278.2 596 478 264 608 304 NA NA NA NA NA NA 39294 XM_029338608.2 190 72 56 127 76 NA NA NA NA NA NA 39295 XM_044319353.1 99 1 92 325 305 Q6NU47 1.61e-33 Serine/threonine-protein kinase pdik1l-A (EC 2.7.11.1) Xenopus laevis (African clawed frog) protein phosphorylation [GO:0006468] GO:0004674; GO:0005524; GO:0005634; GO:0006468; GO:0106310 39296 XM_044319353.1 99 1 92 325 305 Q6NU47 3.19e-27 Serine/threonine-protein kinase pdik1l-A (EC 2.7.11.1) Xenopus laevis (African clawed frog) protein phosphorylation [GO:0006468] GO:0004674; GO:0005524; GO:0005634; GO:0006468; GO:0106310 39297 XR_003822753.2 0 38 56 0 91 NA NA NA NA NA NA 39298 XM_029344541.2 576 254 136 251 166 Q5M9N0 7.19e-29 Coiled-coil domain-containing protein 158 Homo sapiens (Human) NA NA 39299 XM_029345333.2 97 33 11 24 104 Q1PSW8 8.97e-39 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (mLin41) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Mus musculus (Mouse) 3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to organic substance [GO:0071310]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA processing [GO:0035196]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; post-transcriptional regulation of gene expression [GO:0010608]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein metabolic process [GO:0051246]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0001843; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0010608; GO:0017148; GO:0021915; GO:0030371; GO:0035196; GO:0035198; GO:0035278; GO:0043161; GO:0051246; GO:0051865; GO:0060964; GO:0061158; GO:0061630; GO:0071310; GO:0072089; GO:2000177; GO:2000637 39300 XM_044314409.1 35 0 30 19 56 Q2TBP0 1.94e-46 Proteasome subunit beta type-7 (EC 3.4.25.1) Bos taurus (Bovine) proteolysis involved in protein catabolic process [GO:0051603] GO:0004298; GO:0005634; GO:0005737; GO:0005839; GO:0019774; GO:0051603 39301 XR_006393692.1 8 0 9 44 8 NA NA NA NA NA NA 39302 XR_003823861.2 79 33 84 145 207 NA NA NA NA NA NA 39303 XM_044328394.1 976 277 356 83 0 Q505B7 2.06e-50 Protein archease (Protein ZBTB8OS) Mus musculus (Mouse) tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388] GO:0006388; GO:0046872; GO:0072669 39304 XM_044316669.1 84 0 0 31 300 Q923J1 2.45e-159 Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Channel-kinase 1) (Long transient receptor potential channel 7) (LTrpC-7) (LTrpC7) (Transient receptor potential-phospholipase C-interacting kinase) (TRP-PLIK) Mus musculus (Mouse) actomyosin structure organization [GO:0031032]; calcium ion transport [GO:0006816]; calcium-dependent cell-matrix adhesion [GO:0016340]; cation transmembrane transport [GO:0098655]; cellular magnesium ion homeostasis [GO:0010961]; divalent inorganic cation homeostasis [GO:0072507]; memory [GO:0007613]; necroptotic process [GO:0070266]; positive regulation of apoptotic process [GO:0043065]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein tetramerization [GO:0051262] GO:0001726; GO:0003779; GO:0004672; GO:0004674; GO:0005261; GO:0005262; GO:0005524; GO:0005737; GO:0005886; GO:0006468; GO:0006816; GO:0007613; GO:0010961; GO:0016020; GO:0016301; GO:0016340; GO:0017022; GO:0030672; GO:0031032; GO:0043005; GO:0043025; GO:0043065; GO:0043196; GO:0046777; GO:0046872; GO:0051262; GO:0070266; GO:0072507; GO:0098655; GO:0106310 39305 XM_044311665.1 0 15 73 58 60 Q921Y2 1.5e-70 U3 small nucleolar ribonucleoprotein protein IMP3 (U3 snoRNP protein IMP3) Mus musculus (Mouse) ribosomal small subunit biogenesis [GO:0042274]; rRNA processing [GO:0006364] GO:0003735; GO:0005634; GO:0005654; GO:0005730; GO:0006364; GO:0015935; GO:0019843; GO:0030515; GO:0030684; GO:0032040; GO:0034457; GO:0042274 39306 XM_029345081.2 0 0 86 0 0 Q6BZW3 1.04e-30 Protein BTN1 Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica) L-arginine transmembrane transport [GO:1903826]; lysine transport [GO:0015819]; regulation of intracellular pH [GO:0051453] GO:0000324; GO:0005773; GO:0005774; GO:0015819; GO:0022857; GO:0051453; GO:1903826 39307 XR_006395788.1 36 11 30 42 146 NA NA NA NA NA NA 39308 XM_029340726.2 646 555 716 584 650 P52435 5.78e-62 DNA-directed RNA polymerase II subunit RPB11-a (RNA polymerase II subunit B11-a) (RPB11a) (DNA-directed RNA polymerase II subunit J-1) (RNA polymerase II 13.3 kDa subunit) Homo sapiens (Human) transcription by RNA polymerase II [GO:0006366] GO:0001055; GO:0003677; GO:0003899; GO:0005634; GO:0005654; GO:0005665; GO:0006366; GO:0030275; GO:0046983 39309 XM_044308985.1 2661 2639 1564 3043 1622 P97321 1.04e-152 Prolyl endopeptidase FAP (EC 3.4.21.26) (Dipeptidyl peptidase FAP) (EC 3.4.14.5) (Fibroblast activation protein alpha) (FAPalpha) (Gelatine degradation protease FAP) (EC 3.4.21.-) (Integral membrane serine protease) (Post-proline cleaving enzyme) (Serine integral membrane protease) (SIMP) (Surface-expressed protease) (Seprase) [Cleaved into: Antiplasmin-cleaving enzyme FAP, soluble form (APCE) (EC 3.4.14.5) (EC 3.4.21.-) (EC 3.4.21.26)] Mus musculus (Mouse) angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; melanocyte apoptotic process [GO:1902362]; melanocyte proliferation [GO:0097325]; negative regulation of cell proliferation involved in contact inhibition [GO:0060244]; negative regulation of extracellular matrix disassembly [GO:0010716]; negative regulation of extracellular matrix organization [GO:1903054]; positive regulation of execution phase of apoptosis [GO:1900119]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of cell cycle [GO:0051726]; regulation of collagen catabolic process [GO:0010710] GO:0001525; GO:0002020; GO:0004175; GO:0004252; GO:0005178; GO:0005615; GO:0005886; GO:0006508; GO:0007155; GO:0008233; GO:0008236; GO:0008239; GO:0009986; GO:0010710; GO:0010716; GO:0030027; GO:0031258; GO:0032587; GO:0042802; GO:0042803; GO:0043542; GO:0045177; GO:0045178; GO:0051603; GO:0051726; GO:0060244; GO:0070161; GO:0097325; GO:1900119; GO:1902362; GO:1903054; GO:1905368 39310 XM_044314088.1 15 9 25 7 30 NA NA NA NA NA NA 39311 XM_029348585.2 299 265 222 244 326 Q8QZR8 5.93e-57 Cyclin-Q (CDK10-activating cyclin) (Cyclin-M) (Cyclin-related protein FAM58A) (Cyclin-related protein FAM58B) Mus musculus (Mouse) positive regulation of MAPK cascade [GO:0043410]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000307; GO:0005634; GO:0006357; GO:0016538; GO:0030295; GO:0043410; GO:1902749 39312 XM_044319334.1 4 0 0 48 0 NA NA NA NA NA NA 39313 XM_029354321.2 0 17 3 7 0 NA NA NA NA NA NA 39314 XM_029335442.2 1522 877 744 1508 1244 Q80XK6 0 Autophagy-related protein 2 homolog B Mus musculus (Mouse) autophagosome assembly [GO:0000045]; autophagy of mitochondrion [GO:0000422]; late nucleophagy [GO:0044805]; piecemeal microautophagy of the nucleus [GO:0034727]; reticulophagy [GO:0061709] GO:0000045; GO:0000407; GO:0000422; GO:0005789; GO:0005811; GO:0019898; GO:0032266; GO:0034045; GO:0034727; GO:0044805; GO:0061709; GO:0120013 39315 XM_029335442.2 1522 877 744 1508 1244 Q80XK6 7.19e-79 Autophagy-related protein 2 homolog B Mus musculus (Mouse) autophagosome assembly [GO:0000045]; autophagy of mitochondrion [GO:0000422]; late nucleophagy [GO:0044805]; piecemeal microautophagy of the nucleus [GO:0034727]; reticulophagy [GO:0061709] GO:0000045; GO:0000407; GO:0000422; GO:0005789; GO:0005811; GO:0019898; GO:0032266; GO:0034045; GO:0034727; GO:0044805; GO:0061709; GO:0120013 39316 XM_044320877.1 2236 1740 575 1440 660 Q5JL96 2.02e-29 Probable E3 ubiquitin-protein ligase RZFP34 (EC 2.3.2.27) (OsRFP1) (RING zinc-finger protein 34) (OsRZFP34) Oryza sativa subsp. japonica (Rice) protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0005634; GO:0006511; GO:0008270; GO:0016567; GO:0061630 39317 XM_044321463.1 12 723 0 496 14 Q0P4F7 0 Medium-chain acyl-CoA ligase ACSF2, mitochondrial (EC 6.2.1.2) Danio rerio (Zebrafish) (Brachydanio rerio) fatty acid metabolic process [GO:0006631] GO:0005524; GO:0005739; GO:0006631; GO:0031956; GO:0047760 39318 XM_029341496.2 171 134 174 136 299 Q05940 8.19e-90 Synaptic vesicular amine transporter (Monoamine transporter) (Solute carrier family 18 member 2) (Vesicular amine transporter 2) (VAT2) Homo sapiens (Human) aminergic neurotransmitter loading into synaptic vesicle [GO:0015842]; chemical synaptic transmission [GO:0007268]; dopamine transport [GO:0015872]; histamine secretion by mast cell [GO:0002553]; histamine uptake [GO:0051615]; locomotory behavior [GO:0007626]; monoamine transport [GO:0015844]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neurotransmitter loading into synaptic vesicle [GO:0098700]; neurotransmitter transport [GO:0006836]; post-embryonic development [GO:0009791]; response to amphetamine [GO:0001975]; response to toxic substance [GO:0009636]; sequestering of neurotransmitter [GO:0042137]; serotonin secretion by mast cell [GO:0002552]; serotonin uptake [GO:0051610]; somato-dendritic dopamine secretion [GO:0099123] GO:0001975; GO:0002552; GO:0002553; GO:0005335; GO:0005813; GO:0005886; GO:0006836; GO:0007268; GO:0007626; GO:0008021; GO:0008504; GO:0009636; GO:0009791; GO:0015311; GO:0015842; GO:0015844; GO:0015872; GO:0016020; GO:0022857; GO:0030424; GO:0030425; GO:0030667; GO:0030672; GO:0042137; GO:0043195; GO:0043231; GO:0051610; GO:0051615; GO:0070083; GO:0098691; GO:0098700; GO:0099123; GO:1903427 39319 XM_044314845.1 15 0 3 1 10 NA NA NA NA NA NA 39320 XM_044318056.1 5 1 2 0 21 Q92752 2.3e-72 Tenascin-R (TN-R) (Janusin) (Restrictin) Homo sapiens (Human) associative learning [GO:0008306]; axon extension involved in regeneration [GO:0048677]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198]; locomotory exploration behavior [GO:0035641]; long-term synaptic potentiation [GO:0060291]; negative regulation of axon extension involved in regeneration [GO:0048692]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of neuron projection development [GO:0010977]; negative regulation of synaptic transmission [GO:0050805]; neuroblast migration [GO:0097402]; neuromuscular process controlling balance [GO:0050885]; neuron cell-cell adhesion [GO:0007158]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transmission of nerve impulse [GO:0051971]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of cell migration [GO:0030334]; synapse organization [GO:0050808]; synaptic transmission, glutamatergic [GO:0035249]; telencephalon cell migration [GO:0022029] GO:0005102; GO:0005576; GO:0005615; GO:0007155; GO:0007158; GO:0007411; GO:0008306; GO:0009986; GO:0010977; GO:0022029; GO:0022408; GO:0030155; GO:0030198; GO:0030334; GO:0035249; GO:0035641; GO:0045121; GO:0045595; GO:0048677; GO:0048692; GO:0050805; GO:0050808; GO:0050885; GO:0051968; GO:0051971; GO:0060291; GO:0062023; GO:0072534; GO:0090733; GO:0097402; GO:0098685; GO:0098978 39321 XR_006394829.1 383 8 17 388 21 NA NA NA NA NA NA 39322 XM_029338031.2 273 219 0 169 76 NA NA NA NA NA NA 39323 XM_044310253.1 25 4 7 15 31 Q5BJL5 2.96e-57 Protein strawberry notch homolog 1 Rattus norvegicus (Rat) regulation of DNA-templated transcription [GO:0006355]; regulation of response to stimulus [GO:0048583] GO:0005634; GO:0006355; GO:0031490; GO:0042393; GO:0048583 39324 XM_029340888.2 335 236 141 297 468 Q3T9Z9 2.63e-75 Zinc finger-containing ubiquitin peptidase 1 (EC 3.4.19.12) (Lys-63-specific deubiquitinase ZUFSP) (DUB) (Zinc finger with UFM1-specific peptidase domain protein) Mus musculus (Mouse) regulation of gene expression [GO:0010468] GO:0004843; GO:0005634; GO:0005654; GO:0005829; GO:0010468; GO:0046872 39325 XM_044309530.1 201 147 199 133 383 Q9DBW0 2.75e-112 Cytochrome P450 4V2 (Docosahexaenoic acid omega-hydroxylase CYP4V2) (EC 1.14.14.79) (Long-chain fatty acid omega-monooxygenase) (EC 1.14.14.80) Mus musculus (Mouse) fatty acid omega-oxidation [GO:0010430] GO:0005506; GO:0005789; GO:0010430; GO:0020037; GO:0102033 39326 XM_029339689.2 13438 14912 8629 11492 7782 Q5ZI20 5.42e-84 Zinc transporter ZIP13 (Solute carrier family 39 member 13) (Zrt- and Irt-like protein 13) (ZIP-13) Gallus gallus (Chicken) cellular zinc ion homeostasis [GO:0006882]; zinc ion transmembrane transport [GO:0071577] GO:0000139; GO:0005385; GO:0006882; GO:0071577 39327 XM_029334028.2 74 20 0 93 0 NA NA NA NA NA NA 39328 XR_006393237.1 0 25 5 8 33 NA NA NA NA NA NA 39329 XR_006395274.1 38 0 10 2 1 NA NA NA NA NA NA 39330 XM_044317960.1 5 2 157 0 0 NA NA NA NA NA NA 39331 XM_044312769.1 12 9 48 54 8 P18130 5.4e-43 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) Bos taurus (Bovine) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of vasoconstriction [GO:0045907]; regulation of cardiac muscle contraction [GO:0055117] GO:0001996; GO:0004930; GO:0004937; GO:0005634; GO:0005737; GO:0005886; GO:0005901; GO:0007200; GO:0007204; GO:0007267; GO:0031965; GO:0043410; GO:0045907; GO:0046982; GO:0055117; GO:0071880 39332 XM_044311674.1 474 206 236 140 179 Q66KE8 5.43e-70 Coiled-coil domain-containing protein 78 (xCCDC78) Xenopus laevis (African clawed frog) cell projection organization [GO:0030030]; de novo centriole assembly involved in multi-ciliated epithelial cell differentiation [GO:0098535] GO:0005737; GO:0005814; GO:0030030; GO:0098535; GO:0098536 39333 XM_029354712.2 310 233 0 120 0 Q3S8M4 8.56e-95 Elongation of very long chain fatty acids protein 4 (EC 2.3.1.199) (3-keto acyl-CoA synthase ELOVL4) (ELOVL fatty acid elongase 4) (ELOVL FA elongase 4) (Very long chain 3-ketoacyl-CoA synthase 4) (Very long chain 3-oxoacyl-CoA synthase 4) Macaca mulatta (Rhesus macaque) fatty acid elongation, monounsaturated fatty acid [GO:0034625]; fatty acid elongation, polyunsaturated fatty acid [GO:0034626]; fatty acid elongation, saturated fatty acid [GO:0019367]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; sphingolipid biosynthetic process [GO:0030148]; unsaturated fatty acid biosynthetic process [GO:0006636]; very long-chain fatty acid biosynthetic process [GO:0042761] GO:0005783; GO:0005789; GO:0006636; GO:0009922; GO:0019367; GO:0030148; GO:0034625; GO:0034626; GO:0035338; GO:0042761; GO:0102756 39334 XM_044327330.1 0 0 7 7 34 P51228 3.81e-23 Protein CfxQ homolog Porphyra purpurea (Red seaweed) (Ulva purpurea) NA GO:0005524; GO:0009507; GO:0016887 39335 XM_029330153.2 180 62 118 106 197 NA NA NA NA NA NA 39336 XM_029333141.2 0 13 0 111 46 NA NA NA NA NA NA 39337 XM_044316887.1 14414 14998 11964 18828 19935 NA NA NA NA NA NA 39338 XM_044311697.1 52 91 62 162 238 Q96T58 7.32e-62 Msx2-interacting protein (SMART/HDAC1-associated repressor protein) (SPEN homolog) Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of neurogenesis [GO:0050769]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0003677; GO:0003714; GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0006357; GO:0007219; GO:0017053; GO:0045892; GO:0050769; GO:0061629; GO:0070062 39339 XM_044311697.1 52 91 62 162 238 Q96T58 6.59e-59 Msx2-interacting protein (SMART/HDAC1-associated repressor protein) (SPEN homolog) Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of neurogenesis [GO:0050769]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0003677; GO:0003714; GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0006357; GO:0007219; GO:0017053; GO:0045892; GO:0050769; GO:0061629; GO:0070062 39340 XM_029350380.2 19 88 16 17 26 Q9DBU3 8.54e-177 Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) Mus musculus (Mouse) cellular response to dsDNA [GO:1990786]; cellular response to dsRNA [GO:0071359]; cellular response to virus [GO:0098586]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; maturation of SSU-rRNA [GO:0030490]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of MDA-5 signaling pathway [GO:0039534]; negative regulation of protein-containing complex assembly [GO:0031333]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-beta production [GO:0032728]; protein phosphorylation [GO:0006468] GO:0004674; GO:0005524; GO:0005829; GO:0006468; GO:0030490; GO:0030688; GO:0031333; GO:0032728; GO:0039534; GO:0043124; GO:0045087; GO:0045089; GO:0046872; GO:0051607; GO:0071359; GO:0089720; GO:0098586; GO:0106310; GO:1990786 39341 XM_029333215.2 277 362 253 363 643 NA NA NA NA NA NA 39342 XR_006397987.1 2077 1290 1177 1571 1275 NA NA NA NA NA NA 39343 XM_044329118.1 8 3 0 12 0 NA NA NA NA NA NA 39344 XM_044326360.1 96 69 68 23 54 NA NA NA NA NA NA 39345 XM_044307721.1 238 186 274 213 322 NA NA NA NA NA NA 39346 XR_006393199.1 0 15 19 17 9 NA NA NA NA NA NA 39347 XM_044314110.1 0 8 0 0 0 NA NA NA NA NA NA 39348 XM_029341740.2 16 4 0 2 0 NA NA NA NA NA NA 39349 XM_029334791.2 1418 550 421 561 371 E9Q7E2 3.98e-106 AT-rich interactive domain-containing protein 2 (ARID domain-containing protein 2) (BRG1-associated factor 200) (BAF200) (Zinc finger protein with activation potential) (Zipzap/p200) Mus musculus (Mouse) cardiac muscle cell proliferation [GO:0060038]; chromatin remodeling [GO:0006338]; circulatory system development [GO:0072359]; coronary artery morphogenesis [GO:0060982]; embryonic organ development [GO:0048568]; heart morphogenesis [GO:0003007]; homeostatic process [GO:0042592]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; nucleosome disassembly [GO:0006337]; positive regulation of cell differentiation [GO:0045597]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of G0 to G1 transition [GO:0070316]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of nucleotide-excision repair [GO:2000819]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000776; GO:0000785; GO:0003007; GO:0003677; GO:0005654; GO:0005667; GO:0005886; GO:0006337; GO:0006338; GO:0006357; GO:0008285; GO:0016363; GO:0016514; GO:0016586; GO:0030071; GO:0030336; GO:0042592; GO:0045582; GO:0045597; GO:0045663; GO:0045944; GO:0046872; GO:0048568; GO:0060038; GO:0060982; GO:0070316; GO:0072359; GO:1905168; GO:2000045; GO:2000781; GO:2000819 39350 XM_044322595.1 0 0 0 14 0 NA NA NA NA NA NA 39351 XM_029337750.2 105 0 0 0 26 P13697 0 NADP-dependent malic enzyme (NADP-ME) (EC 1.1.1.40) (Malic enzyme 1) Rattus norvegicus (Rat) malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; NADP metabolic process [GO:0006739]; protein homotetramerization [GO:0051289]; pyruvate metabolic process [GO:0006090]; regulation of NADP metabolic process [GO:1902031]; response to hormone [GO:0009725] GO:0000287; GO:0004470; GO:0004471; GO:0004473; GO:0005737; GO:0005739; GO:0005829; GO:0006090; GO:0006108; GO:0006734; GO:0006739; GO:0008948; GO:0009725; GO:0030145; GO:0042802; GO:0050661; GO:0051287; GO:0051289; GO:1902031 39352 XR_006392902.1 41 2 25 5 151 NA NA NA NA NA NA 39353 XR_006396933.1 148 43 114 135 277 NA NA NA NA NA NA 39354 XR_006392207.1 4 0 59 38 0 NA NA NA NA NA NA 39355 XM_044319775.1 0 14 6 5 0 NA NA NA NA NA NA 39356 XM_044308924.1 11 1 11 2 28 NA NA NA NA NA NA 39357 XM_029330562.2 0 0 0 0 20 Q9Y5X5 7.86e-31 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (G-protein coupled receptor HLWAR77) (Neuropeptide G-protein coupled receptor) Homo sapiens (Human) detection of abiotic stimulus [GO:0009582]; G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0009582; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 39358 XM_044314283.1 14 17 5 11 29 Q80XJ3 1.89e-69 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 39359 XM_044314283.1 14 17 5 11 29 Q80XJ3 1.31e-63 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 39360 XM_044314283.1 14 17 5 11 29 Q80XJ3 5.41e-60 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 39361 XM_044314283.1 14 17 5 11 29 Q80XJ3 1.9e-58 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 39362 XM_044314283.1 14 17 5 11 29 Q80XJ3 1.89e-57 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 39363 XM_044314283.1 14 17 5 11 29 Q80XJ3 2.17e-57 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 39364 XM_044314283.1 14 17 5 11 29 Q80XJ3 2.04e-52 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 39365 XM_044314283.1 14 17 5 11 29 Q80XJ3 2.99e-50 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 39366 XM_044314283.1 14 17 5 11 29 Q80XJ3 2.91e-49 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 39367 XM_044314283.1 14 17 5 11 29 Q80XJ3 1.11e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 39368 XM_044321679.1 53 43 21 14 54 NA NA NA NA NA NA 39369 XM_029344135.2 620 484 111 420 657 O22943 9.89e-89 Probable glycosyltransferase STELLO1 (EC 2.4.-.-) Arabidopsis thaliana (Mouse-ear cress) plant-type cell wall cellulose biosynthetic process [GO:0052324]; regulation of plant-type cell wall cellulose biosynthetic process [GO:2001009] GO:0000139; GO:0005768; GO:0005794; GO:0005802; GO:0016757; GO:0042802; GO:0052324; GO:2001009 39370 XM_044310357.1 27 61 170 223 340 NA NA NA NA NA NA 39371 XM_044322570.1 368 401 217 368 347 NA NA NA NA NA NA 39372 XM_044310088.1 40 9 163 33 292 NA NA NA NA NA NA 39373 XM_029354857.2 2530 1689 1763 3705 2592 Q9H2X6 8.45e-179 Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1) Homo sapiens (Human) adult walking behavior [GO:0007628]; anterior/posterior pattern specification [GO:0009952]; cell population proliferation [GO:0008283]; cellular response to hypoxia [GO:0071456]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; erythrocyte differentiation [GO:0030218]; eye development [GO:0001654]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; iris morphogenesis [GO:0061072]; lens induction in camera-type eye [GO:0060235]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; PML body organization [GO:0030578]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA binding [GO:0043388]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein binding [GO:0032092]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein phosphorylation [GO:0006468]; regulation of cell cycle [GO:0051726]; regulation of signal transduction by p53 class mediator [GO:1901796]; retina layer formation [GO:0010842]; SMAD protein signal transduction [GO:0060395]; smoothened signaling pathway [GO:0007224]; transforming growth factor beta receptor signaling pathway [GO:0007179]; voluntary musculoskeletal movement [GO:0050882] GO:0000122; GO:0001654; GO:0001934; GO:0003713; GO:0003714; GO:0004672; GO:0004674; GO:0004713; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0006468; GO:0006978; GO:0007179; GO:0007224; GO:0007628; GO:0008283; GO:0008284; GO:0009952; GO:0010494; GO:0010842; GO:0016604; GO:0016605; GO:0018105; GO:0018107; GO:0030182; GO:0030218; GO:0030511; GO:0030514; GO:0030578; GO:0032092; GO:0042771; GO:0043388; GO:0043524; GO:0045766; GO:0045893; GO:0045944; GO:0046330; GO:0046332; GO:0046790; GO:0048596; GO:0050882; GO:0051091; GO:0051402; GO:0051726; GO:0060059; GO:0060235; GO:0060395; GO:0061072; GO:0061629; GO:0071456; GO:0090575; GO:0097193; GO:0106310; GO:1901796; GO:2000059 39374 XM_029353879.2 334 273 212 325 395 Q3U4G3 6.1e-81 Xyloside xylosyltransferase 1 (EC 2.4.2.62) (UDP-xylose:alpha-xyloside alpha-1,3-xylosyltransferase) Mus musculus (Mouse) O-glycan processing [GO:0016266] GO:0000287; GO:0005789; GO:0016266; GO:0030145; GO:0035252; GO:0140560 39375 XM_044308830.1 11 0 1 12 0 Q95LR0 1.49e-64 Cilia- and flagella-associated protein 91 (CFAP91) (AMY-1-associating protein expressed in testis 1) (AAT-1) (MYCBP/AMY-1-associated testis-expressed protein 1) (Protein MAATS1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) axonemal central apparatus assembly [GO:1904158]; cell differentiation [GO:0030154]; cilium movement [GO:0003341]; spermatogenesis [GO:0007283] GO:0003341; GO:0005739; GO:0005930; GO:0007283; GO:0030154; GO:0031514; GO:1904158 39376 XR_006395153.1 0 0 9 0 0 NA NA NA NA NA NA 39377 XM_029357650.2 74 23 18 43 72 NA NA NA NA NA NA 39378 XM_044324587.1 1406 173 152 461 182 P35546 1.19e-75 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; anatomical structure morphogenesis [GO:0009653]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006919; GO:0007156; GO:0007158; GO:0007169; GO:0007399; GO:0009410; GO:0009653; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030182; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0098797; GO:2001241 39379 XM_029349664.2 273 154 155 314 193 P51611 0 Host cell factor 1 (HCF) (HCF-1) (C1 factor) (VCAF) (VP16 accessory protein) [Cleaved into: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6] Mesocricetus auratus (Golden hamster) cell cycle [GO:0007049]; chromatin organization [GO:0006325]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of mitotic cell cycle [GO:0045931]; protein stabilization [GO:0050821] GO:0000122; GO:0000123; GO:0003682; GO:0003713; GO:0005634; GO:0005737; GO:0006325; GO:0007049; GO:0043025; GO:0045931; GO:0048188; GO:0050821; GO:0071339 39380 XM_029349664.2 273 154 155 314 193 P51611 2.75e-75 Host cell factor 1 (HCF) (HCF-1) (C1 factor) (VCAF) (VP16 accessory protein) [Cleaved into: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6] Mesocricetus auratus (Golden hamster) cell cycle [GO:0007049]; chromatin organization [GO:0006325]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of mitotic cell cycle [GO:0045931]; protein stabilization [GO:0050821] GO:0000122; GO:0000123; GO:0003682; GO:0003713; GO:0005634; GO:0005737; GO:0006325; GO:0007049; GO:0043025; GO:0045931; GO:0048188; GO:0050821; GO:0071339 39381 XM_044329327.1 90 81 83 178 177 Q63HM2 3.32e-175 Pecanex-like protein 4 (Hepatitis C virus F protein-binding protein 2) (HCV F protein-binding protein 2) (Pecanex homolog protein 4) Homo sapiens (Human) NA GO:0016020 39382 XM_044324940.1 232 13 152 217 186 Q08BV2 4.6e-143 tRNA wybutosine-synthesizing protein 5 (EC 1.14.11.42) (tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-C(2))-hydroxylase) Danio rerio (Zebrafish) (Brachydanio rerio) wybutosine biosynthetic process [GO:0031591] GO:0000049; GO:0005506; GO:0016706; GO:0031591; GO:0042803; GO:0102524 39383 XM_044315317.1 2197 943 1664 2267 2346 Q2EMV9 5.21e-46 Protein mono-ADP-ribosyltransferase PARP14 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (Collaborator of STAT6) (CoaSt6) (Poly [ADP-ribose] polymerase 14) (PARP-14) Mus musculus (Mouse) innate immune response [GO:0045087]; negative regulation of gene expression [GO:0010629]; negative regulation of type II interferon-mediated signaling pathway [GO:0060336]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; positive regulation of interleukin-4-mediated signaling pathway [GO:1902216]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein poly-ADP-ribosylation [GO:0070212] GO:0003714; GO:0003950; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0010629; GO:0016779; GO:0019899; GO:0042531; GO:0042532; GO:0045087; GO:0060336; GO:0070212; GO:0070403; GO:1902216; GO:1990404 39384 XM_044323801.1 12 0 1 342 8 NA NA NA NA NA NA 39385 XM_029342273.2 385 403 469 224 328 Q98TB4 4.12e-24 Growth/differentiation factor 8 (Myostatin) (MSTN) Oreochromis mossambicus (Mozambique tilapia) (Tilapia mossambica) NA GO:0005125; GO:0005615; GO:0008083 39386 XM_044309321.1 21 4 0 0 8 NA NA NA NA NA NA 39387 XM_044321070.1 1511 1305 795 1643 997 B2GUZ1 0 Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.4.19.12) (Deubiquitinating enzyme 4) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) Rattus norvegicus (Rat) negative regulation of protein ubiquitination [GO:0031397]; protein deubiquitination [GO:0016579]; protein localization to cell surface [GO:0034394]; regulation of protein stability [GO:0031647]; spliceosomal tri-snRNP complex assembly [GO:0000244]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000244; GO:0004843; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0006511; GO:0016579; GO:0031397; GO:0031647; GO:0031685; GO:0034394; GO:0042802; GO:0046872 39388 XR_006396983.1 22 14 7 36 30 NA NA NA NA NA NA 39389 XR_003824585.2 50 11 5 53 75 NA NA NA NA NA NA 39390 XM_044319224.1 148 65 48 117 112 Q6P4W8 0 Pachytene checkpoint protein 2 homolog (Thyroid hormone receptor interactor 13 homolog) (Thyroid receptor-interacting protein 13 homolog) (TR-interacting protein 13 homolog) (TRIP-13 homolog) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) double-strand break repair [GO:0006302]; oogenesis [GO:0048477]; reciprocal meiotic recombination [GO:0007131]; spermatogenesis [GO:0007283]; synaptonemal complex assembly [GO:0007130] GO:0005524; GO:0006302; GO:0007130; GO:0007131; GO:0007283; GO:0016887; GO:0048477 39391 XM_029350905.2 152 50 20 73 183 NA NA NA NA NA NA 39392 XM_044311973.1 17 0 13 0 40 NA NA NA NA NA NA 39393 XR_006391646.1 24 104 154 39 48 NA NA NA NA NA NA 39394 XM_029357039.2 429 0 63 0 0 Q9Z0K8 2.56e-144 Pantetheinase (EC 3.5.1.92) (Pantetheine hydrolase) (Vascular non-inflammatory molecule 1) (Vanin-1) Mus musculus (Mouse) acute inflammatory response [GO:0002526]; cell-cell adhesion [GO:0098609]; chronic inflammatory response [GO:0002544]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; pantothenate metabolic process [GO:0015939]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of T cell differentiation in thymus [GO:0033089] GO:0002526; GO:0002544; GO:0005886; GO:0006954; GO:0015939; GO:0016020; GO:0017159; GO:0033089; GO:0034235; GO:0045087; GO:0098609; GO:1902177 39395 XM_044310317.1 73 49 64 37 0 NA NA NA NA NA NA 39396 XM_029345010.2 306 187 267 354 151 NA NA NA NA NA NA 39397 XM_044309833.1 575 367 451 768 1466 Q29RU2 1.6e-35 Oncoprotein-induced transcript 3 protein Bos taurus (Bovine) NA GO:0005509; GO:0005635 39398 XM_029340974.2 249 276 151 360 646 NA NA NA NA NA NA 39399 XM_044314024.1 93 0 0 32 116 A6NE52 9.01e-70 WD repeat-containing protein 97 Homo sapiens (Human) NA NA 39400 XM_044315546.1 0 15 3 0 3 Q09575 1.82e-36 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 39401 XM_044317368.1 479 495 308 513 615 Q80XJ3 2.74e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 39402 XM_044317368.1 479 495 308 513 615 Q80XJ3 6.41e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 39403 XM_044317368.1 479 495 308 513 615 Q80XJ3 1.07e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 39404 XM_044317368.1 479 495 308 513 615 Q80XJ3 8.94e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 39405 XM_044323003.1 16 0 5 0 0 P10090 8.24e-145 Protein white (EC 7.6.2.-) (EC 7.6.2.6) (ATP-binding cassette transporter sub-family G member white) (Broad substrate specificity ATP-binding cassette transporter white) Drosophila melanogaster (Fruit fly) aminergic neurotransmitter loading into synaptic vesicle [GO:0015842]; biogenic amine biosynthetic process [GO:0042401]; cGMP transport [GO:0070731]; compound eye pigmentation [GO:0048072]; eye pigment metabolic process [GO:0042441]; eye pigment precursor transport [GO:0006856]; gravitaxis [GO:0042332]; guanine transport [GO:0015854]; histamine uptake [GO:0051615]; male courtship behavior [GO:0008049]; memory [GO:0007613]; ommochrome biosynthetic process [GO:0006727]; riboflavin transport [GO:0032218]; transmembrane transport [GO:0055085]; tryptophan transport [GO:0015827]; xanthine transport [GO:0042906] GO:0005275; GO:0005524; GO:0005886; GO:0006727; GO:0006856; GO:0007613; GO:0008049; GO:0008558; GO:0015196; GO:0015208; GO:0015827; GO:0015842; GO:0015854; GO:0016020; GO:0016887; GO:0022857; GO:0030659; GO:0031409; GO:0031410; GO:0032217; GO:0032218; GO:0042332; GO:0042401; GO:0042441; GO:0042626; GO:0042906; GO:0042907; GO:0048072; GO:0048770; GO:0051615; GO:0055085; GO:0070731; GO:0090741; GO:0098793; GO:1905948 39406 XR_003824652.2 0 0 0 0 6 Q640B4 1.76e-158 Crossover junction endonuclease MUS81 (EC 3.1.22.-) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) DNA catabolic process, endonucleolytic [GO:0000737]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302] GO:0000737; GO:0003677; GO:0006302; GO:0006310; GO:0008821; GO:0043596; GO:0046872 39407 XM_029351344.2 877 994 400 633 447 Q7ZXH2 8.62e-27 E3 SUMO-protein ligase NSE2 (EC 2.3.2.-) (E3 SUMO-protein transferase NSE2) (MMS21 homolog) (Non-structural maintenance of chromosomes element 2 homolog) (Non-SMC element 2 homolog) Xenopus laevis (African clawed frog) cell cycle [GO:0007049]; cell division [GO:0051301]; cellular senescence [GO:0090398]; double-strand break repair via homologous recombination [GO:0000724]; positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; regulation of macromolecule metabolic process [GO:0060255]; telomere maintenance via recombination [GO:0000722] GO:0000722; GO:0000724; GO:0000781; GO:0007049; GO:0008270; GO:0016605; GO:0019789; GO:0030915; GO:0034184; GO:0045842; GO:0051301; GO:0060255; GO:0090398 39408 XM_029326283.2 24 6 31 2 128 NA NA NA NA NA NA 39409 XM_044308869.1 848 984 773 807 654 Q8BIZ6 5.38e-76 Smad nuclear-interacting protein 1 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; miRNA processing [GO:0035196]; mRNA splicing, via spliceosome [GO:0000398]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000398; GO:0003729; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0007249; GO:0035196; GO:0071005 39410 XM_029341501.2 8 0 7 94 24 NA NA NA NA NA NA 39411 XR_006393345.1 30 17 64 42 119 NA NA NA NA NA NA 39412 XM_044313925.1 62 490 107 119 113 NA NA NA NA NA NA 39413 XM_029338365.2 2036 1935 1372 1862 1842 O88637 4.22e-154 Ethanolamine-phosphate cytidylyltransferase (EC 2.7.7.14) (CTP:phosphoethanolamine cytidylyltransferase) (Phosphorylethanolamine transferase) Rattus norvegicus (Rat) phosphatidylethanolamine biosynthetic process [GO:0006646] GO:0004306; GO:0005737; GO:0006646 39414 XM_044327556.1 5486 6284 3259 8618 6940 Q90593 0 Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein) Gallus gallus (Chicken) cellular response to glucose starvation [GO:0042149]; cellular response to interleukin-4 [GO:0071353]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; positive regulation of cell migration [GO:0030335]; positive regulation of protein ubiquitination [GO:0031398]; post-translational protein targeting to membrane, translocation [GO:0031204]; protein refolding [GO:0042026]; toxin transport [GO:1901998]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0005524; GO:0005634; GO:0005737; GO:0005739; GO:0005788; GO:0005789; GO:0005793; GO:0005829; GO:0005886; GO:0006983; GO:0008180; GO:0009986; GO:0016020; GO:0016887; GO:0019904; GO:0021589; GO:0021680; GO:0030335; GO:0030433; GO:0030496; GO:0030512; GO:0030968; GO:0031072; GO:0031204; GO:0031333; GO:0031398; GO:0031625; GO:0034620; GO:0034663; GO:0035437; GO:0042026; GO:0042149; GO:0042470; GO:0043022; GO:0043066; GO:0044183; GO:0051082; GO:0051085; GO:0051787; GO:0071353; GO:0140662; GO:1901998; GO:1903895 39415 XR_003824190.2 30 24 3 26 38 NA NA NA NA NA NA 39416 XR_006398102.1 3 17 0 3 18 NA NA NA NA NA NA 39417 XM_029349591.2 157 118 98 0 105 NA NA NA NA NA NA 39418 XM_029330316.2 3057 1853 2671 2380 2875 P31400 0 V-type proton ATPase catalytic subunit A (V-ATPase subunit A) (EC 7.1.2.2) (V-ATPase 69 kDa subunit) (Vacuolar proton pump subunit alpha) Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm) NA GO:0005524; GO:0033180; GO:0046933; GO:0046961 39419 XM_029357472.2 2308 2367 1746 1426 1309 Q9D531 1.68e-42 Nucleoredoxin-like protein 2 (Rod-derived cone viability factor 2) (RdCVF2) Mus musculus (Mouse) photoreceptor cell maintenance [GO:0045494]; sensory perception of smell [GO:0007608]; visual perception [GO:0007601] GO:0007601; GO:0007608; GO:0045494 39420 XM_044326233.1 86 49 86 123 44 NA NA NA NA NA NA 39421 XM_044321983.1 0 14 15 9 1 NA NA NA NA NA NA 39422 XM_029347577.2 124 109 42 102 50 NA NA NA NA NA NA 39423 XR_006393977.1 530 776 310 3575 633 NA NA NA NA NA NA 39424 XM_044309983.1 23 8 19 20 35 O00602 1.38e-77 Ficolin-1 (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin-alpha) (M-ficolin) Homo sapiens (Human) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation, lectin pathway [GO:0001867]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of viral entry into host cell [GO:0046597]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of opsonization [GO:1903028]; protein localization to cell surface [GO:0034394]; proteolysis [GO:0006508]; recognition of apoptotic cell [GO:0043654] GO:0001664; GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005576; GO:0005581; GO:0005615; GO:0006508; GO:0007186; GO:0009897; GO:0030246; GO:0031232; GO:0032757; GO:0033691; GO:0034394; GO:0034774; GO:0038187; GO:0043654; GO:0046597; GO:0046872; GO:0062023; GO:0097367; GO:1903028; GO:1904813; GO:1905370 39425 XM_044310148.1 88 23 30 7 57 NA NA NA NA NA NA 39426 XM_044328429.1 17 42 37 18 18 NA NA NA NA NA NA 39427 XM_044312895.1 0 0 0 28 0 Q7ZU90 0 Chromodomain-helicase-DNA-binding protein 1-like (EC 3.6.4.-) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to DNA damage stimulus [GO:0006974]; chromatin remodeling [GO:0006338]; DNA repair [GO:0006281] GO:0000166; GO:0003678; GO:0005524; GO:0005634; GO:0006281; GO:0006338; GO:0006974; GO:0016887; GO:0031491; GO:0035861; GO:0140566; GO:0140658; GO:0160004 39428 XM_029331324.2 0 0 0 1 196 O95935 5.92e-94 T-box transcription factor TBX18 (T-box protein 18) Homo sapiens (Human) cell fate specification [GO:0001708]; cochlea morphogenesis [GO:0090103]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation [GO:0060829]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of SA node cell action potential [GO:0098907]; regulation of transcription by RNA polymerase II [GO:0006357]; sinoatrial node cell development [GO:0060931]; sinoatrial node cell fate commitment [GO:0060930]; sinoatrial node development [GO:0003163]; smooth muscle cell differentiation [GO:0051145]; somitogenesis [GO:0001756]; ureter development [GO:0072189] GO:0000785; GO:0000976; GO:0000978; GO:0000981; GO:0001227; GO:0001708; GO:0001756; GO:0003163; GO:0005634; GO:0005654; GO:0006357; GO:0016331; GO:0042803; GO:0045893; GO:0051145; GO:0060829; GO:0060930; GO:0060931; GO:0072189; GO:0090103; GO:0090571; GO:0098907; GO:1990837 39429 XM_029357833.2 8922 9060 6465 10603 9689 Q9CZX7 2.42e-51 Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase (Type 2 PtdIns-4,5-P2 4-Ptase) (EC 3.1.3.78) (PtdIns-4,5-P2 4-Ptase II) (Transmembrane protein 55A) Mus musculus (Mouse) negative regulation of phagocytosis [GO:0050765]; phosphatidylinositol dephosphorylation [GO:0046856] GO:0005765; GO:0005886; GO:0030670; GO:0031902; GO:0034597; GO:0046856; GO:0050765 39430 XM_029354496.2 13 24 0 9 0 Q8N531 8.73e-28 F-box/LRR-repeat protein 6 (F-box and leucine-rich repeat protein 6) (F-box protein FBL6) (FBL6A) Homo sapiens (Human) entrainment of circadian clock by photoperiod [GO:0043153]; G2/M transition of mitotic cell cycle [GO:0000086]; proteolysis [GO:0006508]; regulation of cell cycle [GO:0051726]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0000086; GO:0004842; GO:0005634; GO:0005829; GO:0006508; GO:0019005; GO:0031146; GO:0043153; GO:0051726 39431 XM_029347779.2 290 246 169 242 262 Q7L8A9 8.86e-77 Tubulinyl-Tyr carboxypeptidase 1 (EC 3.4.17.17) (Tubulin carboxypeptidase 1) (Tyrosine carboxypeptidase 1) (TTCP 1) (Vasohibin-1) Homo sapiens (Human) angiogenesis [GO:0001525]; cell cycle [GO:0007049]; labyrinthine layer blood vessel development [GO:0060716]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of lymphangiogenesis [GO:1901491]; proteolysis [GO:0006508]; regulation of angiogenesis [GO:0045765]; regulation of cell cycle [GO:0051726]; regulation of cellular senescence [GO:2000772]; response to wounding [GO:0009611] GO:0001525; GO:0001937; GO:0003779; GO:0004181; GO:0005615; GO:0005737; GO:0005783; GO:0006508; GO:0007049; GO:0009611; GO:0016525; GO:0043537; GO:0045177; GO:0045765; GO:0051726; GO:0060716; GO:0106423; GO:1901491; GO:2000772 39432 XM_029341395.2 2502 2698 1712 1848 2496 Q13367 0 AP-3 complex subunit beta-2 (Adaptor protein complex AP-3 subunit beta-2) (Adaptor-related protein complex 3 subunit beta-2) (Beta-3B-adaptin) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP) Homo sapiens (Human) anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; clathrin-coated vesicle cargo loading, AP-3-mediated [GO:0035654]; intracellular protein transport [GO:0006886]; intracellular transport [GO:0046907]; synaptic vesicle coating [GO:0016183]; synaptic vesicle recycling [GO:0036465]; vesicle-mediated transport [GO:0016192] GO:0005769; GO:0005794; GO:0006886; GO:0008089; GO:0016183; GO:0016192; GO:0030123; GO:0030665; GO:0035654; GO:0036465; GO:0046907; GO:0048490; GO:0097708; GO:0098793; GO:1904115 39433 XM_029341395.2 2502 2698 1712 1848 2496 Q13367 4.9e-49 AP-3 complex subunit beta-2 (Adaptor protein complex AP-3 subunit beta-2) (Adaptor-related protein complex 3 subunit beta-2) (Beta-3B-adaptin) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP) Homo sapiens (Human) anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; clathrin-coated vesicle cargo loading, AP-3-mediated [GO:0035654]; intracellular protein transport [GO:0006886]; intracellular transport [GO:0046907]; synaptic vesicle coating [GO:0016183]; synaptic vesicle recycling [GO:0036465]; vesicle-mediated transport [GO:0016192] GO:0005769; GO:0005794; GO:0006886; GO:0008089; GO:0016183; GO:0016192; GO:0030123; GO:0030665; GO:0035654; GO:0036465; GO:0046907; GO:0048490; GO:0097708; GO:0098793; GO:1904115 39434 XM_029350250.2 492 267 75 346 292 O18638 4.88e-52 Out at first protein Drosophila virilis (Fruit fly) NA NA 39435 XR_006393922.1 41 2 25 5 151 NA NA NA NA NA NA 39436 XM_044309257.1 40 0 0 0 0 NA NA NA NA NA NA 39437 XM_029350855.2 1 0 15 0 26 NA NA NA NA NA NA 39438 XM_029328754.2 215 158 118 231 228 Q8IZ69 1.17e-147 tRNA (uracil-5-)-methyltransferase homolog A (EC 2.1.1.35) (mRNA (uracil-5-)-methyltransferase TRMT2A) (EC 2.1.1.-) Homo sapiens (Human) mRNA processing [GO:0006397] GO:0003723; GO:0005829; GO:0006397; GO:0008169; GO:0030697 39439 XR_006396594.1 14 6 0 2 0 P18321 8.06e-56 Profilin Clypeaster japonicus (Sand dollar) regulation of cellular component biogenesis [GO:0044087] GO:0003779; GO:0005737; GO:0005856; GO:0044087 39440 XM_029348132.2 549 454 412 621 896 Q93YS4 3.35e-70 ABC transporter G family member 22 (ABC transporter ABCG.22) (AtABCG22) (White-brown complex homolog protein 23) (AtWBC23) Arabidopsis thaliana (Mouse-ear cress) response to water deprivation [GO:0009414]; transmembrane transport [GO:0055085]; transpiration [GO:0010148] GO:0005524; GO:0009414; GO:0010148; GO:0016020; GO:0016887; GO:0042626; GO:0055085; GO:0140359 39441 XM_029348132.2 549 454 412 621 896 Q93YS4 2.25e-42 ABC transporter G family member 22 (ABC transporter ABCG.22) (AtABCG22) (White-brown complex homolog protein 23) (AtWBC23) Arabidopsis thaliana (Mouse-ear cress) response to water deprivation [GO:0009414]; transmembrane transport [GO:0055085]; transpiration [GO:0010148] GO:0005524; GO:0009414; GO:0010148; GO:0016020; GO:0016887; GO:0042626; GO:0055085; GO:0140359 39442 XM_029328567.2 673 169 167 614 352 Q7TN88 1.24e-81 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 39443 XM_029328567.2 673 169 167 614 352 Q7TN88 1.49e-47 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 39444 XM_029328567.2 673 169 167 614 352 Q7TN88 3.61e-35 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 39445 XM_029352480.2 807 724 459 695 1089 P53610 2.74e-137 Geranylgeranyl transferase type-1 subunit beta (EC 2.5.1.59) (Geranylgeranyl transferase type I subunit beta) (GGTase-I-beta) (Type I protein geranyl-geranyltransferase subunit beta) Rattus norvegicus (Rat) negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; protein geranylgeranylation [GO:0018344]; protein prenylation [GO:0018342]; response to cytokine [GO:0034097] GO:0004661; GO:0004662; GO:0005953; GO:0008270; GO:0008284; GO:0018342; GO:0018344; GO:0034097; GO:0045787; GO:0051771; GO:1901363 39446 XM_044314533.1 3 3 9 0 17 NA NA NA NA NA NA 39447 XM_029330111.2 129 62 56 102 149 O08954 1.41e-56 Zinc finger protein SNAI2 (Neural crest transcription factor Slug) (Protein snail homolog 2) Rattus norvegicus (Rat) cartilage morphogenesis [GO:0060536]; cell migration [GO:0016477]; cell migration involved in endocardial cushion formation [GO:0003273]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to ionizing radiation [GO:0071479]; desmosome disassembly [GO:0035921]; DNA-templated transcription [GO:0006351]; endothelial cell migration [GO:0043542]; epithelial cell migration [GO:0010631]; epithelial to mesenchymal transition [GO:0001837]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; epithelium development [GO:0060429]; hematopoietic stem cell proliferation [GO:0071425]; myeloid cell apoptotic process [GO:0033028]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell adhesion involved in substrate-bound cell migration [GO:0006933]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of chondrocyte differentiation [GO:0032331]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of hematopoietic stem cell proliferation [GO:1902034]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902230]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of myeloid cell apoptotic process [GO:0033033]; negative regulation of stem cell proliferation [GO:2000647]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vitamin D biosynthetic process [GO:0010957]; negative regulation of vitamin D receptor signaling pathway [GO:0070563]; neural crest cell development [GO:0014032]; Notch signaling pathway [GO:0007219]; osteoblast differentiation [GO:0001649]; pigmentation [GO:0043473]; positive regulation of cell migration [GO:0030335]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of histone acetylation [GO:0035066]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of chemokine production [GO:0032642]; regulation of DNA-templated transcription [GO:0006355]; regulation of osteoblast differentiation [GO:0045667]; response to radiation [GO:0009314]; roof of mouth development [GO:0060021]; sensory perception of sound [GO:0007605]; substrate-dependent cell migration [GO:0006929]; white fat cell differentiation [GO:0050872] GO:0000122; GO:0000785; GO:0000977; GO:0000978; GO:0000981; GO:0001227; GO:0001649; GO:0001837; GO:0003198; GO:0003273; GO:0003682; GO:0005634; GO:0005737; GO:0006351; GO:0006355; GO:0006929; GO:0006933; GO:0007219; GO:0007605; GO:0009314; GO:0010631; GO:0010839; GO:0010957; GO:0014032; GO:0016477; GO:0030335; GO:0032331; GO:0032642; GO:0033028; GO:0033033; GO:0033629; GO:0035066; GO:0035921; GO:0043066; GO:0043473; GO:0043518; GO:0043542; GO:0043565; GO:0044344; GO:0045600; GO:0045667; GO:0046872; GO:0050872; GO:0060021; GO:0060429; GO:0060536; GO:0060693; GO:0070563; GO:0070888; GO:0071364; GO:0071425; GO:0071479; GO:0090090; GO:1902034; GO:1902230; GO:1990837; GO:2000647; GO:2000810; GO:2000811; GO:2001240 39448 XM_044316698.1 27 0 0 79 46 NA NA NA NA NA NA 39449 XM_029338977.2 105 19 96 21 61 NA NA NA NA NA NA 39450 XM_029344907.2 357 104 247 498 321 Q6QNK2 1.46e-79 Adhesion G-protein coupled receptor D1 (G-protein coupled receptor 133) (G-protein coupled receptor PGR25) Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0005654; GO:0005886; GO:0007166; GO:0007186; GO:0007189; GO:0016020 39451 XR_006393855.1 4 32 27 5 22 NA NA NA NA NA NA 39452 XR_003826778.2 108 47 46 41 103 NA NA NA NA NA NA 39453 XM_029340570.2 709 659 504 896 927 Q59990 1.32e-28 Putative cytochrome P450 120 (EC 1.14.-.-) Synechocystis sp. (strain PCC 6803 / Kazusa) sterol metabolic process [GO:0016125] GO:0004497; GO:0005506; GO:0016125; GO:0016491; GO:0016705; GO:0020037 39454 XM_044323132.1 1053 474 378 1992 1693 P15989 2.16e-38 Collagen alpha-3(VI) chain Gallus gallus (Chicken) cell adhesion [GO:0007155]; negative regulation of peptidase activity [GO:0010466] GO:0004867; GO:0005581; GO:0005615; GO:0007155; GO:0010466; GO:0062023 39455 XM_044323132.1 1053 474 378 1992 1693 P15989 8.73e-24 Collagen alpha-3(VI) chain Gallus gallus (Chicken) cell adhesion [GO:0007155]; negative regulation of peptidase activity [GO:0010466] GO:0004867; GO:0005581; GO:0005615; GO:0007155; GO:0010466; GO:0062023 39456 XM_044317593.1 4303 3413 3096 3672 4997 NA NA NA NA NA NA 39457 XM_044325360.1 168 74 109 90 107 NA NA NA NA NA NA 39458 XM_044312551.1 42 0 3 0 132 NA NA NA NA NA NA 39459 XM_044312894.1 125 33 105 0 251 Q7ZU90 0 Chromodomain-helicase-DNA-binding protein 1-like (EC 3.6.4.-) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to DNA damage stimulus [GO:0006974]; chromatin remodeling [GO:0006338]; DNA repair [GO:0006281] GO:0000166; GO:0003678; GO:0005524; GO:0005634; GO:0006281; GO:0006338; GO:0006974; GO:0016887; GO:0031491; GO:0035861; GO:0140566; GO:0140658; GO:0160004 39460 XM_029346270.2 7 0 0 0 33 NA NA NA NA NA NA 39461 XM_029337730.2 239 194 261 219 187 Q9DEB5 1.19e-173 Frizzled-10-A (Fz-10A) (Xfz10-A) Xenopus laevis (African clawed frog) Wnt signaling pathway [GO:0016055] GO:0004930; GO:0005886; GO:0016055 39462 XR_003827240.2 64 31 36 35 51 NA NA NA NA NA NA 39463 XM_029331472.2 2310 2656 1064 3022 2450 Q9D2U5 8.88e-26 N-alpha-acetyltransferase 38, NatC auxiliary subunit (LSM domain-containing protein 1) Mus musculus (Mouse) negative regulation of apoptotic process [GO:0043066] GO:0005634; GO:0005654; GO:0005737; GO:0005844; GO:0031417; GO:0043066 39464 XM_044328503.1 37 97 4 0 23 Q8L7C9 2.52e-31 Glutathione S-transferase U20 (AtGSTU20) (EC 2.5.1.18) (FIN219-interacting protein 1) (GST class-tau member 20) Arabidopsis thaliana (Mouse-ear cress) glutathione metabolic process [GO:0006749]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407] GO:0004364; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0006749; GO:0009407; GO:0009507; GO:0009629; GO:0019899; GO:0043295; GO:0048046; GO:2000030 39465 XM_029344455.2 0 0 0 0 21 Q8N865 2.08e-29 Uncharacterized protein C7orf31 Homo sapiens (Human) NA GO:0005737; GO:0005813 39466 XR_006397827.1 71 28 26 102 97 NA NA NA NA NA NA 39467 XM_044316688.1 520 247 298 646 538 Q80VL1 8.71e-62 Tudor and KH domain-containing protein (Tudor domain-containing protein 2) Mus musculus (Mouse) fertilization [GO:0009566]; male meiotic nuclear division [GO:0007140]; P granule organization [GO:0030719]; piRNA processing [GO:0034587]; spermatogenesis [GO:0007283] GO:0003723; GO:0005737; GO:0005739; GO:0005829; GO:0007140; GO:0007283; GO:0009566; GO:0030719; GO:0034587; GO:0043186; GO:0071546; GO:0071547 39468 XM_029340945.2 224 224 154 210 465 Q7ZVH1 5.92e-43 Membrane progestin receptor gamma-A (mPR gamma-A) (Progestin and adipoQ receptor family member V-A) Danio rerio (Zebrafish) (Brachydanio rerio) oogenesis [GO:0048477] GO:0005496; GO:0016020; GO:0038023; GO:0048477 39469 XM_044308771.1 39 42 23 0 36 NA NA NA NA NA NA 39470 XM_029331735.2 3525 3199 2492 4005 4147 NA NA NA NA NA NA 39471 XM_044310951.1 11 0 0 2 0 NA NA NA NA NA NA 39472 XM_029340040.2 917 1348 576 1457 1342 A8K855 2.99e-123 EF-hand calcium-binding domain-containing protein 7 Homo sapiens (Human) positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein localization to ciliary membrane [GO:1903569]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0005509; GO:0005929; GO:0019898; GO:0042307; GO:0045944; GO:0060170; GO:0098797; GO:1903569 39473 XR_003826790.2 7 61 0 1 41 NA NA NA NA NA NA 39474 XM_044308800.1 0 0 122 105 0 NA NA NA NA NA NA 39475 XM_044318140.1 105 0 37 0 21 NA NA NA NA NA NA 39476 XR_006395657.1 0 181 150 41 59 NA NA NA NA NA NA 39477 XM_044320576.1 0 2 3 13 9 NA NA NA NA NA NA 39478 XM_029331428.2 1420 951 851 1468 1643 P30825 1.77e-135 High affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (Ecotropic retroviral leukemia receptor homolog) (Ecotropic retrovirus receptor homolog) (Solute carrier family 7 member 1) (System Y+ basic amino acid transporter) Homo sapiens (Human) amino acid import across plasma membrane [GO:0089718]; amino acid transport [GO:0006865]; L-amino acid transport [GO:0015807]; L-arginine import across plasma membrane [GO:0097638]; L-arginine transmembrane transport [GO:1903826]; L-histidine import across plasma membrane [GO:1903810]; L-ornithine transmembrane transport [GO:1903352]; lysine transport [GO:0015819]; ornithine transport [GO:0015822]; positive regulation of T cell proliferation [GO:0042102]; transport across blood-brain barrier [GO:0150104] GO:0000064; GO:0001618; GO:0005290; GO:0005886; GO:0006865; GO:0009925; GO:0015171; GO:0015174; GO:0015189; GO:0015807; GO:0015819; GO:0015822; GO:0016020; GO:0016323; GO:0016324; GO:0032991; GO:0042102; GO:0061459; GO:0089718; GO:0097638; GO:0150104; GO:1903352; GO:1903810; GO:1903826 39479 XM_029334000.2 179 53 170 294 160 D2IYS2 1.27e-72 Tyrosine-protein kinase receptor torso (EC 2.7.10.1) Bombyx mori (Silk moth) NA GO:0004714; GO:0005524; GO:0005886; GO:0046872 39480 XM_029355476.2 155 58 11 0 146 P10894 0 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (EC 3.1.4.11) (PLC-154) (Phosphoinositide phospholipase C-beta-1) (Phospholipase C-beta-1) (PLC-beta-1) Bos taurus (Bovine) interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-15-mediated signaling pathway [GO:0035723]; lipid catabolic process [GO:0016042]; memory [GO:0007613]; phosphatidylinositol metabolic process [GO:0046488]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of JNK cascade [GO:0046330] GO:0004435; GO:0005096; GO:0005509; GO:0005516; GO:0005546; GO:0005737; GO:0005829; GO:0007613; GO:0016042; GO:0016607; GO:0019899; GO:0031965; GO:0035722; GO:0035723; GO:0046330; GO:0046488; GO:0048015; GO:0070498 39481 XR_006392968.1 10 0 8 0 55 NA NA NA NA NA NA 39482 XM_029332377.2 324 152 139 276 185 O42231 2.5e-92 Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) Chelon auratus (Golden grey mullet) (Liza aurata) NA GO:0005506; GO:0005789; GO:0020037; GO:0070330 39483 XM_044314988.1 2 17 15 56 1 NA NA NA NA NA NA 39484 XM_044320638.1 892 458 361 606 663 Q8NEN9 1.29e-59 PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR-104) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; lipid transport [GO:0006869]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrion-endoplasmic reticulum membrane tethering [GO:1990456]; regulation of cell morphogenesis [GO:0022604] GO:0005739; GO:0005789; GO:0006869; GO:0007010; GO:0008289; GO:0016020; GO:0022604; GO:0044233; GO:0046872; GO:0051560; GO:1990456 39485 XM_044320638.1 892 458 361 606 663 Q8NEN9 3.55e-23 PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR-104) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; lipid transport [GO:0006869]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrion-endoplasmic reticulum membrane tethering [GO:1990456]; regulation of cell morphogenesis [GO:0022604] GO:0005739; GO:0005789; GO:0006869; GO:0007010; GO:0008289; GO:0016020; GO:0022604; GO:0044233; GO:0046872; GO:0051560; GO:1990456 39486 XM_044327379.1 92 32 11 30 55 NA NA NA NA NA NA 39487 XM_044308708.1 0 5 1 10 0 NA NA NA NA NA NA 39488 XM_044315011.1 11 0 0 0 1 NA NA NA NA NA NA 39489 XR_003825440.2 34 7 9 39 24 NA NA NA NA NA NA 39490 XM_044307291.1 0 10 0 0 0 Q5VRY0 1.18e-59 DEAD-box ATP-dependent RNA helicase 39 (EC 3.6.4.13) Oryza sativa subsp. japonica (Rice) mitochondrial large ribosomal subunit assembly [GO:1902775] GO:0003723; GO:0003724; GO:0005524; GO:0005739; GO:0016887; GO:1902775 39491 XM_044319572.1 660 1153 127 420 311 NA NA NA NA NA NA 39492 XM_044322859.1 4 23 0 0 171 NA NA NA NA NA NA 39493 XM_044320401.1 10 0 20 16 9 NA NA NA NA NA NA 39494 XM_044325472.1 1014 769 656 1227 1211 Q5ZIJ9 1.86e-142 E3 ubiquitin-protein ligase MIB2 (EC 2.3.2.27) (Mind bomb homolog 2) (RING-type E3 ubiquitin transferase MIB2) Gallus gallus (Chicken) Notch signaling pathway [GO:0007219]; protein ubiquitination [GO:0016567] GO:0004842; GO:0005737; GO:0007219; GO:0008270; GO:0016567 39495 XM_044325472.1 1014 769 656 1227 1211 Q5ZIJ9 1.86e-61 E3 ubiquitin-protein ligase MIB2 (EC 2.3.2.27) (Mind bomb homolog 2) (RING-type E3 ubiquitin transferase MIB2) Gallus gallus (Chicken) Notch signaling pathway [GO:0007219]; protein ubiquitination [GO:0016567] GO:0004842; GO:0005737; GO:0007219; GO:0008270; GO:0016567 39496 XM_044325472.1 1014 769 656 1227 1211 Q5ZIJ9 1.13e-59 E3 ubiquitin-protein ligase MIB2 (EC 2.3.2.27) (Mind bomb homolog 2) (RING-type E3 ubiquitin transferase MIB2) Gallus gallus (Chicken) Notch signaling pathway [GO:0007219]; protein ubiquitination [GO:0016567] GO:0004842; GO:0005737; GO:0007219; GO:0008270; GO:0016567 39497 XM_029346326.2 84 0 0 48 121 O00305 3.33e-63 Voltage-dependent L-type calcium channel subunit beta-4 (CAB4) (Calcium channel voltage-dependent subunit beta 4) Homo sapiens (Human) adult walking behavior [GO:0007628]; cAMP metabolic process [GO:0046058]; cellular response to leukemia inhibitory factor [GO:1990830]; chemical synaptic transmission [GO:0007268]; detection of light stimulus involved in visual perception [GO:0050908]; gamma-aminobutyric acid secretion [GO:0014051]; gamma-aminobutyric acid signaling pathway [GO:0007214]; muscle cell development [GO:0055001]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; neuromuscular junction development [GO:0007528]; neuronal action potential propagation [GO:0019227]; Peyer's patch development [GO:0048541]; positive regulation of protein localization to nucleolus [GO:1904751]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; regulation of synaptic vesicle exocytosis [GO:2000300]; regulation of voltage-gated calcium channel activity [GO:1901385]; spleen development [GO:0048536]; synaptic transmission, glutamatergic [GO:0035249]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538] GO:0005730; GO:0005829; GO:0005886; GO:0005891; GO:0007214; GO:0007268; GO:0007528; GO:0007628; GO:0008285; GO:0009898; GO:0014051; GO:0016607; GO:0019227; GO:0019901; GO:0035249; GO:0045202; GO:0046058; GO:0048536; GO:0048538; GO:0048541; GO:0050852; GO:0050908; GO:0055001; GO:0098793; GO:0098978; GO:0099626; GO:1901385; GO:1901387; GO:1904751; GO:1990830; GO:2000134; GO:2000300 39498 XM_044319402.1 10 3 2 5 83 Q6AZB8 7.53e-34 Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0004518; GO:0005634; GO:0005737; GO:0046872 39499 XM_044322242.1 552 0 11 16 1598 P46939 1.82e-69 Utrophin (Dystrophin-related protein 1) (DRP-1) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; muscle contraction [GO:0006936]; muscle organ development [GO:0007517]; positive regulation of cell-matrix adhesion [GO:0001954]; regulation of sodium ion transmembrane transporter activity [GO:2000649] GO:0001954; GO:0003779; GO:0005178; GO:0005654; GO:0005737; GO:0005856; GO:0005886; GO:0006936; GO:0007517; GO:0008270; GO:0016010; GO:0016020; GO:0017166; GO:0019901; GO:0030036; GO:0030054; GO:0030175; GO:0030864; GO:0031527; GO:0031594; GO:0032991; GO:0042383; GO:0042995; GO:0045211; GO:0051015; GO:0070062; GO:2000649 39500 XR_003826904.2 405 601 275 384 262 NA NA NA NA NA NA 39501 XM_044307358.1 60 10 0 0 0 NA NA NA NA NA NA 39502 XM_044320458.1 85 415 0 57 310 NA NA NA NA NA NA 39503 XR_003825063.2 197 184 40 170 145 NA NA NA NA NA NA 39504 XM_029332554.2 1305 1202 616 1554 1986 Q9Y2Z0 1.89e-71 Protein SGT1 homolog (Protein 40-6-3) (Sgt1) (Suppressor of G2 allele of SKP1 homolog) Homo sapiens (Human) mitotic cell cycle [GO:0000278]; protein stabilization [GO:0050821]; regulation of protein stability [GO:0031647] GO:0000151; GO:0000278; GO:0000776; GO:0005634; GO:0005829; GO:0031647; GO:0032991; GO:0050821; GO:0051087 39505 XM_029357669.2 8123 8470 5777 6813 4051 NA NA NA NA NA NA 39506 XM_044312727.1 40 37 21 35 75 NA NA NA NA NA NA 39507 XR_006393297.1 0 58 16 46 49 NA NA NA NA NA NA 39508 XM_029342777.2 380 325 266 225 345 C9JJ37 9.95e-60 BTB/POZ domain-containing protein 19 Homo sapiens (Human) NA NA 39509 XM_029342060.2 158 94 58 40 43 Q7YRH6 8.22e-59 Phosphatidylethanolamine N-methyltransferase (PEAMT) (PEMT) (EC 2.1.1.17) (EC 2.1.1.71) (Phospholipid methyltransferase) (PLMT) Bos taurus (Bovine) methylation [GO:0032259]; phosphatidylcholine biosynthetic process [GO:0006656] GO:0000773; GO:0004608; GO:0005789; GO:0006656; GO:0031966; GO:0032259; GO:0080101 39510 XR_003828307.2 20 7 17 29 26 NA NA NA NA NA NA 39511 XM_029324273.2 80 83 29 46 63 NA NA NA NA NA NA 39512 XR_003826667.2 637 901 338 651 602 NA NA NA NA NA NA 39513 XM_044316078.1 2607 1606 1656 3054 2086 Q7TT36 1.98e-89 Adhesion G protein-coupled receptor A3 (G-protein coupled receptor 125) Mus musculus (Mouse) cell surface receptor signaling pathway [GO:0007166] GO:0004930; GO:0005886; GO:0007166; GO:0009897 39514 XM_029343331.2 181 226 140 146 228 NA NA NA NA NA NA 39515 XM_029333960.2 332 352 322 174 248 A0A061IR73 0 Peroxisomal ATPase PEX6 (EC 3.6.4.-) (Peroxin-6) (Peroxisomal biogenesis factor 6) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) protein import into peroxisome matrix [GO:0016558]; protein import into peroxisome matrix, receptor recycling [GO:0016562]; protein import into peroxisome matrix, translocation [GO:0016561]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335] GO:0001750; GO:0005524; GO:0005778; GO:0005829; GO:0008022; GO:0016558; GO:0016561; GO:0016562; GO:0016887; GO:0043335; GO:0044877; GO:0050821; GO:0140036; GO:0140318 39516 XM_044319849.1 0 5 0 14 0 NA NA NA NA NA NA 39517 XM_029327046.2 38924 20931 20451 32806 14533 O49447 1.67e-115 ADP,ATP carrier protein 3, mitochondrial (ADP/ATP translocase 3) (Adenine nucleotide translocator 3) (ANT 3) Arabidopsis thaliana (Mouse-ear cress) mitochondrial ADP transmembrane transport [GO:0140021]; mitochondrial ATP transmembrane transport [GO:1990544]; purine nucleotide transport [GO:0015865] GO:0005471; GO:0005739; GO:0005743; GO:0005886; GO:0009941; GO:0015865; GO:0016020; GO:0140021; GO:1990544 39518 XR_006394447.1 3984 4507 1293 56 1450 NA NA NA NA NA NA 39519 XM_044313483.1 5 4 9 10 33 NA NA NA NA NA NA 39520 XM_029327161.2 3178 3004 1833 3113 2055 O60268 1.02e-22 Uncharacterized protein KIAA0513 Homo sapiens (Human) NA GO:0005737 39521 XM_029327161.2 3178 3004 1833 3113 2055 O60268 7.41e-21 Uncharacterized protein KIAA0513 Homo sapiens (Human) NA GO:0005737 39522 XM_029331318.2 3 25 47 0 19 P54131 7.09e-90 Neuronal acetylcholine receptor subunit alpha-7 Bos taurus (Bovine) calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; cognition [GO:0050890]; ion transmembrane transport [GO:0034220]; negative regulation of tumor necrosis factor production [GO:0032720]; nervous system process [GO:0050877]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAPK cascade [GO:0043410]; regulation of membrane potential [GO:0042391]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271] GO:0001540; GO:0001666; GO:0005231; GO:0005886; GO:0005892; GO:0006816; GO:0006874; GO:0007165; GO:0007268; GO:0007271; GO:0008284; GO:0015464; GO:0015643; GO:0017081; GO:0022848; GO:0030594; GO:0032720; GO:0034220; GO:0035094; GO:0042166; GO:0042391; GO:0042803; GO:0043005; GO:0043410; GO:0045202; GO:0045211; GO:0045766; GO:0050877; GO:0050890; GO:1904315 39523 XM_029337107.2 52 11 25 4 3 Q5F2F2 6.12e-61 Protein ABHD15 (Alpha/beta hydrolase domain-containing protein 15) (Abhydrolase domain-containing protein 15) Mus musculus (Mouse) cellular lipid metabolic process [GO:0044255] GO:0005576; GO:0034338; GO:0044255; GO:0047372 39524 XM_029346826.2 0 306 135 24 28 Q9ULL1 1.56e-94 Pleckstrin homology domain-containing family G member 1 Homo sapiens (Human) regulation of small GTPase mediated signal transduction [GO:0051056] GO:0005085; GO:0005654; GO:0005829; GO:0051056 39525 XM_029346759.2 1081 913 517 1257 1091 NA NA NA NA NA NA 39526 XM_029342657.2 96 76 85 43 321 NA NA NA NA NA NA 39527 XM_029347591.2 275 160 143 263 233 NA NA NA NA NA NA 39528 XM_044308335.1 1067 592 643 1905 941 NA NA NA NA NA NA 39529 XM_029324958.2 276 1360 232 289 197 NA NA NA NA NA NA 39530 XR_006392345.1 12 15 0 7 0 Q99570 1.74e-25 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 39531 XM_044308268.1 9 32 50 38 30 NA NA NA NA NA NA 39532 XM_044327364.1 205 457 326 406 233 Q8R151 0 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 39533 XM_044327364.1 205 457 326 406 233 Q8R151 2.23e-77 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 39534 XM_044327593.1 846 648 428 940 721 D3YVL2 0 Cilia- and flagella-associated protein 70 (Tetratricopeptide repeat protein 18) (TPR repeat protein 18) Mus musculus (Mouse) cilium assembly [GO:0060271]; cilium movement [GO:0003341] GO:0003341; GO:0005930; GO:0031514; GO:0036064; GO:0036126; GO:0036157; GO:0060271 39535 XM_029349989.2 1355 784 785 871 765 O42411 2.5e-48 Type I iodothyronine deiodinase (EC 1.21.99.4) (5DI) (DIOI) (Type 1 DI) (Type-I 5'-deiodinase) Gallus gallus (Chicken) hormone biosynthetic process [GO:0042446]; thyroid hormone metabolic process [GO:0042403] GO:0004800; GO:0005789; GO:0042403; GO:0042446 39536 XM_029354743.2 201 79 165 165 96 Q3S8M4 3.24e-90 Elongation of very long chain fatty acids protein 4 (EC 2.3.1.199) (3-keto acyl-CoA synthase ELOVL4) (ELOVL fatty acid elongase 4) (ELOVL FA elongase 4) (Very long chain 3-ketoacyl-CoA synthase 4) (Very long chain 3-oxoacyl-CoA synthase 4) Macaca mulatta (Rhesus macaque) fatty acid elongation, monounsaturated fatty acid [GO:0034625]; fatty acid elongation, polyunsaturated fatty acid [GO:0034626]; fatty acid elongation, saturated fatty acid [GO:0019367]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; sphingolipid biosynthetic process [GO:0030148]; unsaturated fatty acid biosynthetic process [GO:0006636]; very long-chain fatty acid biosynthetic process [GO:0042761] GO:0005783; GO:0005789; GO:0006636; GO:0009922; GO:0019367; GO:0030148; GO:0034625; GO:0034626; GO:0035338; GO:0042761; GO:0102756 39537 XM_029340143.2 27 28 17 64 22 NA NA NA NA NA NA 39538 XM_029332980.2 6 0 4 8 6 Q92667 3.21e-38 A-kinase anchor protein 1, mitochondrial (A-kinase anchor protein 149 kDa) (AKAP 149) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Protein kinase A-anchoring protein 1) (PRKA1) (Spermatid A-kinase anchor protein 84) (S-AKAP84) Homo sapiens (Human) antiviral innate immune response [GO:0140374]; apoptotic process [GO:0006915] GO:0003723; GO:0005739; GO:0005741; GO:0005829; GO:0006915; GO:0016020; GO:0034237; GO:0140374 39539 XM_029329523.2 525 230 245 437 403 Q3TYL0 4.45e-114 IQ motif and ankyrin repeat domain-containing protein 1 Mus musculus (Mouse) NA NA 39540 XM_029336080.2 45 83 25 162 66 P27889 9.6e-88 Hepatocyte nuclear factor 1-beta (HNF-1-beta) (HNF-1B) (Homeoprotein LFB3) (Transcription factor 2) (TCF-2) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; apoptotic process [GO:0006915]; branching morphogenesis of an epithelial tube [GO:0048754]; circadian regulation of gene expression [GO:0032922]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic morphogenesis [GO:0048598]; endocrine pancreas development [GO:0031018]; endoderm development [GO:0007492]; endoderm formation [GO:0001706]; endodermal cell fate specification [GO:0001714]; epithelial cell proliferation [GO:0050673]; epithelium development [GO:0060429]; genitalia development [GO:0048806]; hepatoblast differentiation [GO:0061017]; hepatocyte differentiation [GO:0070365]; hindbrain development [GO:0030902]; inner cell mass cell differentiation [GO:0001826]; insulin secretion [GO:0030073]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; liver development [GO:0001889]; mesenchymal cell apoptotic process involved in metanephros development [GO:1900200]; mesonephric duct development [GO:0072177]; mesonephric duct formation [GO:0072181]; mesonephric tubule development [GO:0072164]; negative regulation of apoptotic process [GO:0043066]; negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis [GO:0061296]; negative regulation of mesenchymal cell apoptotic process involved in metanephros development [GO:1900212]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nephric duct development [GO:0072176]; nephric duct formation [GO:0072179]; Notch signaling pathway [GO:0007219]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; pronephric nephron tubule development [GO:0039020]; pronephros development [GO:0048793]; protein-DNA complex assembly [GO:0065004]; regulation of branch elongation involved in ureteric bud branching [GO:0072095]; regulation of pronephros size [GO:0035565]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of Wnt signaling pathway [GO:0030111]; response to glucose [GO:0009749]; response to organic cyclic compound [GO:0014070]; response to xenobiotic stimulus [GO:0009410]; ureteric bud elongation [GO:0060677] GO:0000122; GO:0000976; GO:0000978; GO:0000981; GO:0000987; GO:0001221; GO:0001706; GO:0001714; GO:0001822; GO:0001826; GO:0001889; GO:0003677; GO:0003700; GO:0005634; GO:0005654; GO:0005667; GO:0006357; GO:0006915; GO:0007219; GO:0007492; GO:0009410; GO:0009749; GO:0009952; GO:0010628; GO:0014070; GO:0030073; GO:0030111; GO:0030902; GO:0031018; GO:0032922; GO:0035565; GO:0039020; GO:0042802; GO:0042803; GO:0043066; GO:0043231; GO:0043565; GO:0044877; GO:0045893; GO:0045944; GO:0048557; GO:0048598; GO:0048754; GO:0048793; GO:0048806; GO:0050673; GO:0060261; GO:0060429; GO:0060677; GO:0060993; GO:0061017; GO:0061296; GO:0065004; GO:0070365; GO:0072095; GO:0072164; GO:0072176; GO:0072177; GO:0072179; GO:0072181; GO:1900200; GO:1900212 39541 XM_029349964.2 24 13 7 24 80 A0A0D3QS97 3.24e-32 Palmitoleoyl-protein carboxylesterase notum2 (EC 3.1.1.98) Xenopus laevis (African clawed frog) Wnt signaling pathway [GO:0016055] GO:0005576; GO:0016055; GO:0016787 39542 XR_006396101.1 105 47 40 146 64 NA NA NA NA NA NA 39543 XM_029330305.2 23 344 1033 676 627 Q9IA88 7.82e-157 Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2) Gallus gallus (Chicken) intracellular signal transduction [GO:0035556]; microtubule cytoskeleton organization [GO:0000226]; protein phosphorylation [GO:0006468]; regulation of insulin receptor signaling pathway [GO:0046626] GO:0000226; GO:0000287; GO:0004674; GO:0005524; GO:0005737; GO:0006468; GO:0035556; GO:0046626; GO:0050321; GO:0106310 39544 XR_006391964.1 0 0 0 0 16 NA NA NA NA NA NA 39545 XM_044324161.1 0 0 2 13 0 NA NA NA NA NA NA 39546 XM_044316917.1 481 308 276 270 412 Q9CR27 2.06e-57 WASH complex subunit 3 (Coiled-coil domain-containing protein 53) Mus musculus (Mouse) actin filament polymerization [GO:0030041]; endosomal transport [GO:0016197]; exocytosis [GO:0006887]; protein transport [GO:0015031]; regulation of Arp2/3 complex-mediated actin nucleation [GO:0034315] GO:0006887; GO:0015031; GO:0016197; GO:0030041; GO:0031901; GO:0034315; GO:0071203 39547 XR_006396331.1 43 73 78 73 110 NA NA NA NA NA NA 39548 XM_044316475.1 11 4 0 9 1 NA NA NA NA NA NA 39549 XM_029350450.2 199 101 166 73 51 P70085 1.17e-94 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Oryzias latipes (Japanese rice fish) (Japanese killifish) hormone biosynthetic process [GO:0042446]; progesterone metabolic process [GO:0042448]; steroid biosynthetic process [GO:0006694] GO:0004508; GO:0005506; GO:0006694; GO:0016020; GO:0020037; GO:0042446; GO:0042448; GO:0047442 39550 XM_029355554.2 0 26 0 0 23 NA NA NA NA NA NA 39551 XM_044328984.1 306 343 260 305 145 Q5E9X2 2.56e-137 Dual specificity mitogen-activated protein kinase kinase 6 (MAP kinase kinase 6) (MAPKK 6) (EC 2.7.12.2) (MAPK/ERK kinase 6) (MEK 6) Bos taurus (Bovine) apoptotic process [GO:0006915]; bone development [GO:0060348]; cardiac muscle contraction [GO:0060048]; negative regulation of cold-induced thermogenesis [GO:0120163]; osteoblast differentiation [GO:0001649]; positive regulation of MAP kinase activity [GO:0043406]; stress-activated MAPK cascade [GO:0051403] GO:0001649; GO:0004674; GO:0004708; GO:0004713; GO:0005524; GO:0005654; GO:0005829; GO:0005856; GO:0006915; GO:0019211; GO:0019901; GO:0043406; GO:0043539; GO:0051403; GO:0060048; GO:0060348; GO:0106310; GO:0120163; GO:0140537 39552 XM_044311641.1 86 8 60 37 112 NA NA NA NA NA NA 39553 XM_044314167.1 272 48 62 148 147 NA NA NA NA NA NA 39554 XM_029336234.2 5214 8737 9092 6940 8012 P62907 1.82e-113 60S ribosomal protein L10a Rattus norvegicus (Rat) cytoplasmic translation [GO:0002181]; maturation of LSU-rRNA [GO:0000470]; response to ethanol [GO:0045471]; translation [GO:0006412] GO:0000470; GO:0002181; GO:0003723; GO:0003735; GO:0006412; GO:0014069; GO:0022625; GO:0022626; GO:0042788; GO:0045202; GO:0045471 39555 XR_006395847.1 111 118 111 54 84 NA NA NA NA NA NA 39556 XM_044322691.1 28 0 14 10 67 Q95LU3 5.82e-60 Fibrinogen C domain-containing protein 1 Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0008061; GO:0016020; GO:0046872 39557 XM_044316865.1 0 0 0 56 39 NA NA NA NA NA NA 39558 XM_044320514.1 0 0 24 0 40 NA NA NA NA NA NA 39559 XM_044316565.1 193 167 43 119 104 NA NA NA NA NA NA 39560 XM_044320066.1 1 0 0 13 9 NA NA NA NA NA NA 39561 XM_029331622.2 304 153 153 101 201 Q90632 1.46e-31 Monocarboxylate transporter 3 (MCT 3) (Retinal epithelial membrane protein) (Solute carrier family 16 member 8) Gallus gallus (Chicken) monocarboxylic acid transport [GO:0015718] GO:0005886; GO:0008028; GO:0015293; GO:0015718; GO:0016020; GO:0016323 39562 XR_006395336.1 2 2 10 7 23 NA NA NA NA NA NA 39563 XM_044312825.1 108 274 100 134 65 Q7ZU45 5.29e-163 Outer dynein arm-docking complex subunit 4 (Tetratricopeptide repeat protein 25) (TPR repeat protein 25) Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of heart left/right asymmetry [GO:0061371]; otolith morphogenesis [GO:0032474]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0005737; GO:0005856; GO:0032474; GO:0036158; GO:0042995; GO:0060271; GO:0061371 39564 XM_029332293.2 941 669 332 853 805 Q4V8I4 6.81e-116 Differentially expressed in FDCP 8 homolog (DEF-8) Rattus norvegicus (Rat) lysosome localization [GO:0032418]; positive regulation of bone resorption [GO:0045780]; positive regulation of ruffle assembly [GO:1900029] GO:0032418; GO:0045780; GO:0046872; GO:1900029 39565 XR_006391525.1 59 31 54 18 24 NA NA NA NA NA NA 39566 XR_006393746.1 33 33 29 55 11 Q99570 0 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 39567 XR_006393746.1 33 33 29 55 11 Q99570 0 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 39568 XM_029340205.2 16 29 21 1 6 NA NA NA NA NA NA 39569 XM_044315319.1 171 97 104 361 162 NA NA NA NA NA NA 39570 XM_044320263.1 0 100 0 163 0 NA NA NA NA NA NA 39571 XM_044326091.1 3 17 0 8 7 Q15818 3.4e-37 Neuronal pentraxin-1 (NP1) (Neuronal pentraxin I) (NP-I) Homo sapiens (Human) axonogenesis involved in innervation [GO:0060385]; cellular response to glucose stimulus [GO:0071333]; cellular response to potassium ion [GO:0035865]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; mitochondrial transport [GO:0006839]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic density assembly [GO:0097107]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962] GO:0005739; GO:0005886; GO:0006839; GO:0007268; GO:0007417; GO:0030133; GO:0035865; GO:0043005; GO:0043083; GO:0043653; GO:0046872; GO:0060385; GO:0071333; GO:0097107; GO:0098962; GO:0098978; GO:0099645 39572 XM_044312030.1 0 26 16 4 57 NA NA NA NA NA NA 39573 XM_044310494.1 75 2 0 65 190 NA NA NA NA NA NA 39574 XM_029356054.2 1959 1534 1092 1598 1380 A4IFE4 3.28e-152 Ras-GEF domain-containing family member 1B Bos taurus (Bovine) positive regulation of GTPase activity [GO:0043547]; Ras protein signal transduction [GO:0007265] GO:0005085; GO:0005769; GO:0005770; GO:0005886; GO:0007265; GO:0030496; GO:0043547 39575 XM_044326292.1 17 18 19 16 53 Q5VU97 1.04e-146 VWFA and cache domain-containing protein 1 (Cache domain-containing protein 1) Homo sapiens (Human) NA GO:0005245; GO:0005891 39576 XM_029334160.2 816 504 275 648 556 Q8IUH5 0 Palmitoyltransferase ZDHHC17 (EC 2.3.1.225) (Acyltransferase ZDHHC17) (EC 2.3.1.-) (DHHC domain-containing cysteine-rich protein 17) (DHHC17) (Huntingtin yeast partner H) (Huntingtin-interacting protein 14) (HIP-14) (Huntingtin-interacting protein 3) (HIP-3) (Huntingtin-interacting protein H) (Putative MAPK-activating protein PM11) (Putative NF-kappa-B-activating protein 205) (Zinc finger DHHC domain-containing protein 17) Homo sapiens (Human) axonogenesis [GO:0007409]; lipoprotein transport [GO:0042953]; peptidyl-L-cysteine S-palmitoylation [GO:0018230]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein palmitoylation [GO:0018345]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of neurotrophin TRK receptor signaling pathway [GO:0051386] GO:0000139; GO:0005102; GO:0005794; GO:0007409; GO:0016235; GO:0016409; GO:0018230; GO:0018345; GO:0019705; GO:0019706; GO:0030660; GO:0042734; GO:0042802; GO:0042953; GO:0042995; GO:0043123; GO:0043231; GO:0051386; GO:0070372; GO:0140439 39577 XM_044318742.1 29 21 127 102 143 Q76KP1 3.21e-58 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Homo sapiens (Human) NA GO:0008376; GO:0032580; GO:0033842 39578 XM_044318742.1 29 21 127 102 143 Q76KP1 8.55e-27 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Homo sapiens (Human) NA GO:0008376; GO:0032580; GO:0033842 39579 XM_029345295.2 68 16 35 38 80 NA NA NA NA NA NA 39580 XM_029337543.2 16 21 6 27 38 NA NA NA NA NA NA 39581 XM_029334883.2 42 26 56 93 49 NA NA NA NA NA NA 39582 XR_006398197.1 40 30 1 13 4 NA NA NA NA NA NA 39583 XM_029334816.2 0 0 0 13 0 NA NA NA NA NA NA 39584 XM_044319219.1 148 103 107 203 218 Q8NCQ5 1.11e-42 F-box only protein 15 Homo sapiens (Human) NA GO:0005829; GO:0019005 39585 XM_029330473.2 760 759 499 280 606 NA NA NA NA NA NA 39586 XM_044323438.1 6 2 153 40 21 NA NA NA NA NA NA 39587 XM_044320021.1 182 6 79 24 215 NA NA NA NA NA NA 39588 XR_006398108.1 41 11 3 14 11 NA NA NA NA NA NA 39589 XR_006391921.1 45 8 5 5 12 NA NA NA NA NA NA 39590 XM_044325197.1 165 28 0 0 57 NA NA NA NA NA NA 39591 XM_044322355.1 13 2 55 0 165 NA NA NA NA NA NA 39592 XM_029344170.2 355 253 227 311 402 Q9H8Y5 1.41e-50 Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744) Homo sapiens (Human) cellular response to hydrogen peroxide [GO:0070301]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0005737; GO:0016020; GO:0030433; GO:0046872; GO:0070301 39593 XM_029344170.2 355 253 227 311 402 Q9H8Y5 1.2e-26 Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744) Homo sapiens (Human) cellular response to hydrogen peroxide [GO:0070301]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0005737; GO:0016020; GO:0030433; GO:0046872; GO:0070301 39594 XM_029344078.2 3519 3398 1990 2976 2362 A5PJY4 8.72e-45 Transmembrane protein 138 Bos taurus (Bovine) cilium assembly [GO:0060271] GO:0005774; GO:0005929; GO:0060271 39595 XM_044318686.1 0 54 0 0 0 Q6GN08 0 NA NA NA NA 39596 XM_044311629.1 12 13 35 3 27 NA NA NA NA NA NA 39597 XM_029335422.2 0 193 0 0 0 NA NA NA NA NA NA 39598 XM_044311875.1 10 0 2 5 20 NA NA NA NA NA NA 39599 XM_044324761.1 1 0 2 0 11 NA NA NA NA NA NA 39600 XM_029339597.2 456 78 178 246 328 Q9W676 1.84e-138 LIM domain-binding protein 2 (LDB-2) (Carboxyl-terminal LIM domain-binding protein 1) (CLIM-1) (LIM domain-binding factor CLIM1) (cLdb2) Gallus gallus (Chicken) negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000122; GO:0005634; GO:0005667; GO:0007399; GO:0030274; GO:0045944 39601 XM_044309504.1 5 0 4 0 64 NA NA NA NA NA NA 39602 XM_029329806.2 523 269 411 899 826 Q868Z9 2.06e-109 Papilin Drosophila melanogaster (Fruit fly) extracellular matrix organization [GO:0030198]; negative regulation of peptidase activity [GO:0010466] GO:0004222; GO:0004867; GO:0005201; GO:0005576; GO:0005604; GO:0010466; GO:0030198; GO:0031012 39603 XM_044319112.1 0 175 0 137 35 NA NA NA NA NA NA 39604 XM_029346612.2 3362 2554 2139 2272 2053 NA NA NA NA NA NA 39605 XM_029329491.2 716 656 469 456 377 Q922M5 3.39e-44 Cell division cycle-associated 7-like protein (Transcription factor RAM2) Mus musculus (Mouse) positive regulation of cell population proliferation [GO:0008284]; regulation of DNA-templated transcription [GO:0006355] GO:0001650; GO:0005634; GO:0005654; GO:0005730; GO:0005829; GO:0006355; GO:0008284 39606 XM_044316062.1 19 1 7 19 10 Q64WY5 6.32e-51 Probable endonuclease 4 (EC 3.1.21.2) (Endodeoxyribonuclease IV) (Endonuclease IV) Bacteroides fragilis (strain YCH46) DNA repair [GO:0006281] GO:0003677; GO:0006281; GO:0008270; GO:0008833 39607 XM_029354423.2 16 3 10 21 66 NA NA NA NA NA NA 39608 XM_044307219.1 161 143 91 160 95 NA NA NA NA NA NA 39609 XM_029358186.2 5290 4761 2904 4917 5920 Q9D7P6 3.41e-74 Iron-sulfur cluster assembly enzyme ISCU (NifU-like N-terminal domain-containing protein) (NifU-like protein) Mus musculus (Mouse) [2Fe-2S] cluster assembly [GO:0044571]; [4Fe-4S] cluster assembly [GO:0044572]; cellular iron ion homeostasis [GO:0006879]; iron ion homeostasis [GO:0055072]; iron-sulfur cluster assembly [GO:0016226]; negative regulation of iron ion import across plasma membrane [GO:1904439]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of mitochondrial electron transport, NADH to ubiquinone [GO:1902958] GO:0005737; GO:0005739; GO:0005759; GO:0005829; GO:0006879; GO:0008198; GO:0008270; GO:0016226; GO:0042803; GO:0044571; GO:0044572; GO:0051537; GO:0055072; GO:0060090; GO:0099128; GO:1902958; GO:1904234; GO:1904439; GO:1990229 39610 XM_029346827.2 80 33 0 0 0 Q9ULL1 1.8e-94 Pleckstrin homology domain-containing family G member 1 Homo sapiens (Human) regulation of small GTPase mediated signal transduction [GO:0051056] GO:0005085; GO:0005654; GO:0005829; GO:0051056 39611 XM_029326050.2 81 52 172 13 52 NA NA NA NA NA NA 39612 XR_006395680.1 33 44 11 310 205 Q8R151 0 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 39613 XR_006395680.1 33 44 11 310 205 Q8R151 2.24e-99 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 39614 XR_006394094.1 0 0 0 12 0 NA NA NA NA NA NA 39615 XR_006397877.1 54 8 2 0 4 NA NA NA NA NA NA 39616 XM_029328083.2 628 1618 599 292 123 Q8I913 1.15e-52 Dermonecrotic toxin LlSicTox-alphaIII3i (EC 4.6.1.-) (LlH13) (Phospholipase D) (PLD) (Sphingomyelin phosphodiesterase D) (SMD) (SMase D) (Sphingomyelinase D) Loxosceles laeta (South American recluse spider) (Scytodes laeta) hemolysis in another organism [GO:0044179]; lipid catabolic process [GO:0016042] GO:0005576; GO:0008081; GO:0016042; GO:0016829; GO:0044179; GO:0046872; GO:0090729 39617 XM_029340216.2 14 151 0 146 0 NA NA NA NA NA NA 39618 XM_029329149.2 0 1 0 0 7 Q12802 2.79e-82 A-kinase anchor protein 13 (AKAP-13) (AKAP-Lbc) (Breast cancer nuclear receptor-binding auxiliary protein) (Guanine nucleotide exchange factor Lbc) (Human thyroid-anchoring protein 31) (Lymphoid blast crisis oncogene) (LBC oncogene) (Non-oncogenic Rho GTPase-specific GTP exchange factor) (Protein kinase A-anchoring protein 13) (PRKA13) (p47) Homo sapiens (Human) adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process [GO:0086023]; adrenergic receptor signaling pathway [GO:0071875]; bone development [GO:0060348]; cardiac muscle cell differentiation [GO:0055007]; cell growth involved in cardiac muscle cell development [GO:0061049]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; nuclear export [GO:0051168]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Rho protein signal transduction [GO:0035025]; regulation of Rho protein signal transduction [GO:0035023]; regulation of sarcomere organization [GO:0060297]; regulation of small GTPase mediated signal transduction [GO:0051056] GO:0005078; GO:0005085; GO:0005634; GO:0005829; GO:0005938; GO:0007186; GO:0007507; GO:0016020; GO:0031267; GO:0035023; GO:0035025; GO:0043123; GO:0043406; GO:0046872; GO:0048471; GO:0051018; GO:0051056; GO:0051168; GO:0055007; GO:0060090; GO:0060297; GO:0060348; GO:0061049; GO:0071875; GO:0086023 39619 XM_044326389.1 10 4 7 605 25 NA NA NA NA NA NA 39620 XM_044312876.1 77 12 32 0 0 NA NA NA NA NA NA 39621 XM_044312780.1 1 2 14 27 0 NA NA NA NA NA NA 39622 XM_029327065.2 0 0 4 164 0 Q8R4K8 0 Pappalysin-1 (EC 3.4.24.79) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase) (Pregnancy-associated plasma protein A) (PAPP-A) Mus musculus (Mouse) cell surface receptor signaling pathway [GO:0007166]; female pregnancy [GO:0007565]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to dexamethasone [GO:0071548]; response to follicle-stimulating hormone [GO:0032354] GO:0004175; GO:0004222; GO:0005576; GO:0005615; GO:0006508; GO:0007166; GO:0007565; GO:0008237; GO:0030163; GO:0032354; GO:0046872; GO:0071548 39623 XM_044317242.1 2 5 12 0 2 NA NA NA NA NA NA 39624 XM_029327106.2 0 44 7 9 0 NA NA NA NA NA NA 39625 XM_044317692.1 13 0 0 0 0 NA NA NA NA NA NA 39626 XM_044324783.1 22 369 136 297 115 NA NA NA NA NA NA 39627 XM_044313091.1 60 75 36 135 65 NA NA NA NA NA NA 39628 XM_044324291.1 114 435 186 133 11 P60882 0 Multiple epidermal growth factor-like domains protein 8 (Multiple EGF-like domains protein 8) (Epidermal growth factor-like protein 4) (EGF-like protein 4) Mus musculus (Mouse) animal organ morphogenesis [GO:0009887]; BMP signaling pathway [GO:0030509]; cell migration involved in gastrulation [GO:0042074]; coronary vasculature development [GO:0060976]; craniofacial suture morphogenesis [GO:0097094]; determination of digestive tract left/right asymmetry [GO:0071907]; determination of heart left/right asymmetry [GO:0061371]; determination of left/right symmetry [GO:0007368]; embryonic heart tube left/right pattern formation [GO:0060971]; embryonic heart tube morphogenesis [GO:0003143]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; epiboly involved in gastrulation with mouth forming second [GO:0055113]; fasciculation of sensory neuron axon [GO:0097155]; left/right pattern formation [GO:0060972]; limb morphogenesis [GO:0035108]; negative regulation of smoothened signaling pathway [GO:0045879]; positive regulation of axon extension involved in axon guidance [GO:0048842]; regulation of gene expression [GO:0010468]; tissue development [GO:0009888] GO:0003143; GO:0005509; GO:0005634; GO:0007368; GO:0009887; GO:0009888; GO:0010468; GO:0016020; GO:0030326; GO:0030509; GO:0035108; GO:0042074; GO:0045879; GO:0048704; GO:0048842; GO:0055113; GO:0060971; GO:0060972; GO:0060976; GO:0061371; GO:0071907; GO:0097094; GO:0097155 39629 XM_029341745.2 26 12 45 8 38 NA NA NA NA NA NA 39630 XM_029337113.2 820 641 281 718 312 A2RV80 5.33e-70 GRAM domain-containing protein 4 Xenopus laevis (African clawed frog) apoptotic process [GO:0006915] GO:0005789; GO:0006915; GO:0031966 39631 XM_029326500.2 0 0 83 57 45 Q9HF54 4.42e-41 GTP-binding protein RHO1 Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii) actin filament organization [GO:0007015]; cortical cytoskeleton organization [GO:0030865]; establishment or maintenance of cell polarity [GO:0007163]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; small GTPase mediated signal transduction [GO:0007264] GO:0003924; GO:0005525; GO:0005856; GO:0005886; GO:0005938; GO:0007015; GO:0007163; GO:0007264; GO:0008360; GO:0019901; GO:0030865; GO:0031410; GO:0032956; GO:0042995 39632 XM_044322224.1 0 1 1 6 2 NA NA NA NA NA NA 39633 XM_044311377.1 12 6 21 29 75 NA NA NA NA NA NA 39634 XR_006396044.1 0 4 0 0 13 NA NA NA NA NA NA 39635 XM_029340014.2 0 10 10 4 6 P70079 0 Creatine kinase U-type, mitochondrial (EC 2.7.3.2) (Acidic-type mitochondrial creatine kinase) (Mia-CK) (Ubiquitous mitochondrial creatine kinase) (U-MtCK) Gallus gallus (Chicken) phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310] GO:0004111; GO:0005524; GO:0005739; GO:0005743; GO:0016301; GO:0016310; GO:0046314 39636 XM_044311793.1 5 115 1 221 142 NA NA NA NA NA NA 39637 XM_029358046.2 306 247 201 219 277 Q5ZI11 1.56e-80 Leucine-rich repeat-containing protein 45 Gallus gallus (Chicken) NA GO:0005737; GO:0005813 39638 XM_029339660.2 29 3 8 32 11 Q91770 5.13e-22 Homeobox protein not2 (Xnot-2) (Xnot2) Xenopus laevis (African clawed frog) negative regulation of DNA-templated transcription [GO:0045892]; notochord formation [GO:0014028] GO:0000981; GO:0003677; GO:0005634; GO:0014028; GO:0045892 39639 XM_029339687.2 1064 713 352 1276 1413 Q08DG6 9.82e-133 Cytochrome c oxidase assembly protein COX15 homolog Bos taurus (Bovine) heme A biosynthetic process [GO:0006784] GO:0005743; GO:0006784; GO:0016653 39640 XM_044320583.1 0 205 10 68 65 NA NA NA NA NA NA 39641 XM_029341746.2 990 507 541 850 322 Q9NZJ4 0 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 39642 XM_029341746.2 990 507 541 850 322 Q9NZJ4 5.51e-44 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 39643 XM_029340192.2 254 243 202 17 249 Q05096 0 Unconventional myosin-Ib (Myosin I alpha) (MMI-alpha) (MMIa) (Myosin heavy chain myr 1) Rattus norvegicus (Rat) actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; actin filament-based movement [GO:0030048]; nervous system development [GO:0007399]; post-Golgi vesicle-mediated transport [GO:0006892]; transferrin transport [GO:0033572]; vesicle transport along actin filament [GO:0030050] GO:0000146; GO:0003774; GO:0003779; GO:0005516; GO:0005524; GO:0005546; GO:0005547; GO:0005737; GO:0005769; GO:0005884; GO:0005886; GO:0005902; GO:0005903; GO:0006892; GO:0007015; GO:0007399; GO:0010008; GO:0015629; GO:0016459; GO:0030048; GO:0030050; GO:0030175; GO:0031982; GO:0032588; GO:0033572; GO:0045177; GO:0048471; GO:0051015; GO:0051017; GO:0071944 39644 XM_044314927.1 0 0 5 37 10 Q2TBP0 2.42e-42 Proteasome subunit beta type-7 (EC 3.4.25.1) Bos taurus (Bovine) proteolysis involved in protein catabolic process [GO:0051603] GO:0004298; GO:0005634; GO:0005737; GO:0005839; GO:0019774; GO:0051603 39645 XM_044324808.1 11 0 0 0 20 Q8CHP8 1.5e-86 Glycerol-3-phosphate phosphatase (G3PP) (EC 3.1.3.21) (Aspartate-based ubiquitous Mg(2+)-dependent phosphatase) (AUM) (EC 3.1.3.48) (Phosphoglycolate phosphatase) (PGP) Mus musculus (Mouse) glycerol biosynthetic process [GO:0006114]; glycerophospholipid metabolic process [GO:0006650]; negative regulation of gluconeogenesis [GO:0045721] GO:0000121; GO:0000287; GO:0004725; GO:0005737; GO:0006114; GO:0006650; GO:0008967; GO:0016791; GO:0043136; GO:0043262; GO:0045721 39646 XM_044313432.1 0 1 11 0 45 NA NA NA NA NA NA 39647 XR_006396396.1 3 15 2 5 8 NA NA NA NA NA NA 39648 XM_044313322.1 285 70 439 102 555 P14381 2.47e-22 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 39649 XM_044313322.1 285 70 439 102 555 P14381 2.47e-22 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 39650 XM_029351078.2 37 281 60 0 14 NA NA NA NA NA NA 39651 XM_029344728.2 2254 945 680 1206 1218 Q5R2J4 7.28e-76 Protein APCDD1 (Adenomatosis polyposis coli down-regulated 1 protein homolog) (PsAPCDD1) Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis) negative regulation of Wnt signaling pathway [GO:0030178]; Wnt signaling pathway [GO:0016055] GO:0005615; GO:0005886; GO:0016055; GO:0017147; GO:0030178 39652 XM_044308269.1 142 26 26 82 123 NA NA NA NA NA NA 39653 XR_006392385.1 8 0 0 8 0 NA NA NA NA NA NA 39654 XM_029333926.2 2303 1194 1061 1769 1197 Q4R979 5.53e-21 RNA-binding protein 4 (RNA-binding motif protein 4) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) cap-independent translational initiation [GO:0002190]; circadian regulation of gene expression [GO:0032922]; circadian regulation of translation [GO:0097167]; enteroendocrine cell differentiation [GO:0035883]; entrainment of circadian clock by photoperiod [GO:0043153]; insulin secretion involved in cellular response to glucose stimulus [GO:0035773]; IRES-dependent translational initiation of linear mRNA [GO:0002192]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; mRNA processing [GO:0006397]; negative regulation of translation [GO:0017148]; negative regulation of translation in response to stress [GO:0032055]; negative regulation of translational initiation [GO:0045947]; pancreas development [GO:0031016]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of translation [GO:0045727]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of nucleocytoplasmic transport [GO:0046822]; response to arsenic-containing substance [GO:0046685]; RNA splicing [GO:0008380] GO:0000381; GO:0002190; GO:0002192; GO:0003723; GO:0003729; GO:0003730; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0006397; GO:0008270; GO:0008380; GO:0010494; GO:0016607; GO:0017148; GO:0030332; GO:0031016; GO:0032055; GO:0032922; GO:0035198; GO:0035278; GO:0035773; GO:0035883; GO:0036002; GO:0043153; GO:0045727; GO:0045947; GO:0046626; GO:0046685; GO:0046822; GO:0048471; GO:0051149; GO:0097157; GO:0097158; GO:0097167 39655 XR_006395569.1 37 66 102 102 144 Q9CQL0 8.38e-28 Protein N-lysine methyltransferase METTL21A (EC 2.1.1.-) (Methyltransferase-like protein 21A) Mus musculus (Mouse) peptidyl-lysine methylation [GO:0018022]; protein methylation [GO:0006479] GO:0005737; GO:0005829; GO:0006479; GO:0008276; GO:0016279; GO:0018022; GO:0018024; GO:0030544; GO:0031072; GO:0032991; GO:0051117 39656 XR_006395569.1 37 66 102 102 144 Q9CQL0 8.38e-28 Protein N-lysine methyltransferase METTL21A (EC 2.1.1.-) (Methyltransferase-like protein 21A) Mus musculus (Mouse) peptidyl-lysine methylation [GO:0018022]; protein methylation [GO:0006479] GO:0005737; GO:0005829; GO:0006479; GO:0008276; GO:0016279; GO:0018022; GO:0018024; GO:0030544; GO:0031072; GO:0032991; GO:0051117 39657 XR_006395569.1 37 66 102 102 144 Q9CQL0 8.38e-28 Protein N-lysine methyltransferase METTL21A (EC 2.1.1.-) (Methyltransferase-like protein 21A) Mus musculus (Mouse) peptidyl-lysine methylation [GO:0018022]; protein methylation [GO:0006479] GO:0005737; GO:0005829; GO:0006479; GO:0008276; GO:0016279; GO:0018022; GO:0018024; GO:0030544; GO:0031072; GO:0032991; GO:0051117 39658 XM_044319027.1 4 9 8 5 11 Q9UHC6 1.14e-31 Contactin-associated protein-like 2 (Cell recognition molecule Caspr2) Homo sapiens (Human) adult behavior [GO:0030534]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell population proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; clustering of voltage-gated potassium channels [GO:0045163]; learning [GO:0007612]; limbic system development [GO:0021761]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuron recognition [GO:0008038]; positive regulation of gap junction assembly [GO:1903598]; protein localization to juxtaparanode region of axon [GO:0071205]; social behavior [GO:0035176]; striatum development [GO:0021756]; superior temporal gyrus development [GO:0071109]; thalamus development [GO:0021794]; transmission of nerve impulse [GO:0019226]; vocal learning [GO:0042297]; vocalization behavior [GO:0071625] GO:0005769; GO:0005794; GO:0007155; GO:0007420; GO:0007612; GO:0008038; GO:0008076; GO:0008283; GO:0009986; GO:0016020; GO:0019226; GO:0019899; GO:0021756; GO:0021761; GO:0021794; GO:0021987; GO:0030424; GO:0030425; GO:0030534; GO:0030673; GO:0031175; GO:0033010; GO:0035176; GO:0042297; GO:0043025; GO:0043204; GO:0044224; GO:0045163; GO:0048812; GO:0071109; GO:0071205; GO:0071625; GO:1903598 39659 XM_029348834.2 2922 3308 3757 3000 1268 Q86V88 3.38e-55 Magnesium-dependent phosphatase 1 (MDP-1) (EC 3.1.3.-) (EC 3.1.3.48) Homo sapiens (Human) NA GO:0003993; GO:0004725; GO:0046872 39660 XM_044311735.1 24 0 0 0 0 A8WG43 2.52e-38 Coiled-coil domain-containing protein 89 (Bc8 orange-interacting protein) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005634; GO:0005737 39661 XM_029338807.2 276 393 150 233 175 NA NA NA NA NA NA 39662 XM_044315069.1 13 19 0 0 32 Q9CYL5 4.11e-23 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Mus musculus (Mouse) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070374 39663 XM_029337492.2 0 0 41 23 0 O09118 0 Netrin-1 Mus musculus (Mouse) animal organ morphogenesis [GO:0009887]; anterior/posterior axon guidance [GO:0033564]; apoptotic process [GO:0006915]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; B cell mediated immunity [GO:0019724]; B cell proliferation [GO:0042100]; Cdc42 protein signal transduction [GO:0032488]; cell population proliferation [GO:0008283]; cell-cell adhesion [GO:0098609]; chemorepulsion of axon [GO:0061643]; dendrite development [GO:0016358]; glial cell proliferation [GO:0014009]; inner ear morphogenesis [GO:0042472]; mammary gland development [GO:0030879]; mammary gland duct morphogenesis [GO:0060603]; motor neuron axon guidance [GO:0008045]; motor neuron migration [GO:0097475]; negative regulation of axon extension [GO:0030517]; neuron migration [GO:0001764]; nuclear migration [GO:0007097]; positive regulation of axon extension [GO:0045773]; positive regulation of cell motility [GO:2000147]; positive regulation of glial cell proliferation [GO:0060252]; Ras protein signal transduction [GO:0007265]; regulation of cell migration [GO:0030334]; regulation of glial cell migration [GO:1903975]; regulation of synapse assembly [GO:0051963]; substrate-dependent cell migration, cell extension [GO:0006930]; T cell mediated immunity [GO:0002456]; tissue development [GO:0009888] GO:0001764; GO:0002456; GO:0005125; GO:0005576; GO:0005604; GO:0005654; GO:0005737; GO:0005829; GO:0006915; GO:0006930; GO:0007097; GO:0007265; GO:0007409; GO:0007411; GO:0008045; GO:0008283; GO:0009887; GO:0009888; GO:0014009; GO:0015629; GO:0016358; GO:0019724; GO:0030334; GO:0030517; GO:0030879; GO:0031012; GO:0032488; GO:0033564; GO:0042100; GO:0042472; GO:0045773; GO:0051963; GO:0060252; GO:0060603; GO:0061643; GO:0062023; GO:0071944; GO:0097475; GO:0098609; GO:1903975; GO:2000147 39664 XM_044310861.1 107 1187 282 176 370 NA NA NA NA NA NA 39665 XM_029355056.2 974 963 468 1346 1334 NA NA NA NA NA NA 39666 XM_029334048.2 0 0 2 0 117 NA NA NA NA NA NA 39667 XM_044315598.1 11 0 16 0 26 NA NA NA NA NA NA 39668 XM_044324563.1 71 62 0 93 0 H1AFJ5 2.84e-39 Amiloride-sensitive sodium channel subunit alpha (Alpha-NaCH) (Epithelial Na(+) channel subunit alpha) (Alpha-ENaC) (Nonvoltage-gated sodium channel 1 subunit alpha) (SCNEA) Neoceratodus forsteri (Australian lungfish) (Ceratodus forsteri) sodium ion transmembrane transport [GO:0035725] GO:0001669; GO:0005737; GO:0015280; GO:0016324; GO:0031514; GO:0034706; GO:0035725 39669 XM_044312111.1 4 42 4 67 4 NA NA NA NA NA NA 39670 XM_044319860.1 2311 1899 677 1231 935 Q8BVR6 1.04e-167 RING finger and SPRY domain-containing protein 1 Mus musculus (Mouse) proteolysis involved in protein catabolic process [GO:0051603] GO:0004842; GO:0005576; GO:0005737; GO:0046872; GO:0051603 39671 XM_029357609.2 1180 1458 850 1637 1155 Q6GR34 2.84e-51 Uncharacterized protein C16orf52 homolog A Xenopus laevis (African clawed frog) NA NA 39672 XM_044316900.1 30 17 31 7 79 NA NA NA NA NA NA 39673 XM_044311212.1 0 1 7 0 0 NA NA NA NA NA NA 39674 XM_029330753.2 831 553 404 633 799 A7RRG3 4.1e-154 Protein AKTIP homolog (Fused toes protein homolog) Nematostella vectensis (Starlet sea anemone) NA NA 39675 XM_044310015.1 1 0 13 2 8 NA NA NA NA NA NA 39676 XM_029336288.2 665 746 567 711 570 NA NA NA NA NA NA 39677 XM_029337324.2 116 69 46 54 97 Q9PVY8 1.61e-38 Forkhead box protein C2-B (FoxC2-B) (FoxC2b) (Fork head domain-related protein 4') (FD-4') (xFD-4') (xFD4 B) Xenopus laevis (African clawed frog) mesoderm development [GO:0007498]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355] GO:0003677; GO:0003700; GO:0005634; GO:0006355; GO:0007498; GO:0043565; GO:0045893; GO:0045944; GO:1990841 39678 XM_044329329.1 774 710 726 916 959 NA NA NA NA NA NA 39679 XR_006395067.1 5 5 23 6 44 P42260 1.09e-84 Glutamate receptor ionotropic, kainate 2 (GluK2) (Glutamate receptor 6) (GluR-6) (GluR6) Rattus norvegicus (Rat) behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; detection of cold stimulus involved in thermoception [GO:0120169]; excitatory postsynaptic potential [GO:0060079]; inhibitory postsynaptic potential [GO:0060080]; ion transmembrane transport [GO:0034220]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; modulation of excitatory postsynaptic potential [GO:0098815]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; potassium ion transmembrane transport [GO:0071805]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of membrane potential [GO:0042391]; regulation of postsynaptic membrane potential [GO:0060078]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; sodium ion transmembrane transport [GO:0035725]; synaptic transmission, glutamatergic [GO:0035249] GO:0000149; GO:0001662; GO:0004970; GO:0005234; GO:0005886; GO:0006874; GO:0007268; GO:0008066; GO:0008328; GO:0014069; GO:0015276; GO:0015277; GO:0016020; GO:0019228; GO:0030165; GO:0030424; GO:0030425; GO:0031624; GO:0031625; GO:0032839; GO:0032983; GO:0034220; GO:0035235; GO:0035249; GO:0035725; GO:0038023; GO:0042391; GO:0042734; GO:0042802; GO:0043025; GO:0043113; GO:0043195; GO:0043204; GO:0043524; GO:0043525; GO:0045202; GO:0045211; GO:0046328; GO:0048169; GO:0048172; GO:0050804; GO:0050806; GO:0051402; GO:0051967; GO:0060078; GO:0060079; GO:0060080; GO:0071805; GO:0097110; GO:0097471; GO:0098686; GO:0098815; GO:0098978; GO:0099171; GO:0099507; GO:0120169; GO:1904315 39680 XR_003826580.2 2 3 2 8 0 NA NA NA NA NA NA 39681 XM_044320912.1 126 32 76 62 225 Q9VBW3 4.63e-52 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 39682 XM_029340602.2 114 160 107 130 128 NA NA NA NA NA NA 39683 XM_029328875.2 0 0 52 264 138 A2ACP1 8.81e-154 Tetratricopeptide repeat protein 39A (TPR repeat protein 39A) Mus musculus (Mouse) NA GO:0005813 39684 XM_029347192.2 838 466 1652 1073 607 NA NA NA NA NA NA 39685 XM_044328898.1 31 0 41 31 36 Q7TN88 5.86e-87 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 39686 XM_044328898.1 31 0 41 31 36 Q7TN88 1.55e-61 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 39687 XR_003823017.1 2 1 12 2 23 NA NA NA NA NA NA 39688 XM_044315925.1 10 0 0 7 7 NA NA NA NA NA NA 39689 XM_029338024.2 61 0 14 0 100 NA NA NA NA NA NA 39690 XM_044307400.1 6 5 0 1 6 NA NA NA NA NA NA 39691 XM_044322443.1 0 294 378 827 243 P00767 7.63e-48 Chymotrypsinogen B (EC 3.4.21.1) [Cleaved into: Chymotrypsin B chain A; Chymotrypsin B chain B; Chymotrypsin B chain C] Bos taurus (Bovine) digestion [GO:0007586]; proteolysis [GO:0006508] GO:0004252; GO:0005615; GO:0006508; GO:0007586 39692 XR_003823720.1 2 1 12 2 23 NA NA NA NA NA NA 39693 XM_044324607.1 24 15 0 18 5 NA NA NA NA NA NA 39694 XR_003828363.2 177 99 171 160 296 NA NA NA NA NA NA 39695 XR_003825955.2 82 84 148 74 65 NA NA NA NA NA NA 39696 XM_044308882.1 0 0 0 49 0 P07949 1.22e-55 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; axon guidance [GO:0007411]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; lymphocyte migration into lymphoid organs [GO:0097021]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; posterior midgut development [GO:0007497]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006468; GO:0006919; GO:0007156; GO:0007158; GO:0007165; GO:0007169; GO:0007411; GO:0007497; GO:0009410; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0038023; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0097021; GO:0098797; GO:2001241 39697 XM_044308882.1 0 0 0 49 0 P07949 1.22e-55 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; axon guidance [GO:0007411]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; lymphocyte migration into lymphoid organs [GO:0097021]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; posterior midgut development [GO:0007497]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006468; GO:0006919; GO:0007156; GO:0007158; GO:0007165; GO:0007169; GO:0007411; GO:0007497; GO:0009410; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0038023; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0097021; GO:0098797; GO:2001241 39698 XM_044326365.1 197 108 74 148 270 NA NA NA NA NA NA 39699 XM_044323404.1 35 0 0 0 0 NA NA NA NA NA NA 39700 XM_044320469.1 391 688 298 282 189 NA NA NA NA NA NA 39701 XM_044328581.1 11 0 0 0 29 Q95LR0 2.67e-67 Cilia- and flagella-associated protein 91 (CFAP91) (AMY-1-associating protein expressed in testis 1) (AAT-1) (MYCBP/AMY-1-associated testis-expressed protein 1) (Protein MAATS1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) axonemal central apparatus assembly [GO:1904158]; cell differentiation [GO:0030154]; cilium movement [GO:0003341]; spermatogenesis [GO:0007283] GO:0003341; GO:0005739; GO:0005930; GO:0007283; GO:0030154; GO:0031514; GO:1904158 39702 XM_044328581.1 11 0 0 0 29 Q95LR0 2.67e-67 Cilia- and flagella-associated protein 91 (CFAP91) (AMY-1-associating protein expressed in testis 1) (AAT-1) (MYCBP/AMY-1-associated testis-expressed protein 1) (Protein MAATS1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) axonemal central apparatus assembly [GO:1904158]; cell differentiation [GO:0030154]; cilium movement [GO:0003341]; spermatogenesis [GO:0007283] GO:0003341; GO:0005739; GO:0005930; GO:0007283; GO:0030154; GO:0031514; GO:1904158 39703 XM_044328581.1 11 0 0 0 29 Q95LR0 2.67e-67 Cilia- and flagella-associated protein 91 (CFAP91) (AMY-1-associating protein expressed in testis 1) (AAT-1) (MYCBP/AMY-1-associated testis-expressed protein 1) (Protein MAATS1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) axonemal central apparatus assembly [GO:1904158]; cell differentiation [GO:0030154]; cilium movement [GO:0003341]; spermatogenesis [GO:0007283] GO:0003341; GO:0005739; GO:0005930; GO:0007283; GO:0030154; GO:0031514; GO:1904158 39704 XM_044323425.1 112 4 259 653 26 Q1G7G9 2.67e-23 TALPID3 protein Gallus gallus (Chicken) centrosome localization [GO:0051642]; cilium assembly [GO:0060271]; motile cilium assembly [GO:0044458]; smoothened signaling pathway [GO:0007224] GO:0005737; GO:0005813; GO:0005814; GO:0007224; GO:0036064; GO:0044458; GO:0051642; GO:0060271 39705 XM_044324572.1 94 66 54 130 2 NA NA NA NA NA NA 39706 XR_006395199.1 0 0 0 124 18 NA NA NA NA NA NA 39707 XR_006397002.1 251 7 58 318 133 NA NA NA NA NA NA 39708 XM_044323244.1 49 38 17 142 35 E7FAM5 1.25e-104 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 39709 XM_029330850.2 15 8 2 4 5 NA NA NA NA NA NA 39710 XM_044317968.1 562 196 38 0 69 NA NA NA NA NA NA 39711 XR_006395983.1 1970 1884 2528 2149 2282 NA NA NA NA NA NA 39712 XM_029339656.2 0 0 28 0 229 Q9WYP5 1.09e-60 Myo-inositol 2-dehydrogenase (EC 1.1.1.18) Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) inositol metabolic process [GO:0006020]; NADPH regeneration [GO:0006740] GO:0000166; GO:0006020; GO:0006740; GO:0016491; GO:0050112 39713 XR_003824789.2 5 34 66 12 11 NA NA NA NA NA NA 39714 XM_044316766.1 2806 2585 1713 4083 2948 NA NA NA NA NA NA 39715 XM_029332727.2 0 0 7 25 0 Q9NUN7 1.87e-61 Alkaline ceramidase 3 (AlkCDase 3) (Alkaline CDase 3) (EC 3.5.1.-) (EC 3.5.1.23) (Alkaline dihydroceramidase SB89) (Alkaline phytoceramidase) (aPHC) Homo sapiens (Human) ceramide catabolic process [GO:0046514]; inflammatory response [GO:0006954]; myelination [GO:0042552]; phytosphingosine biosynthetic process [GO:0071602]; positive regulation of cell population proliferation [GO:0008284]; regulation of programmed cell death [GO:0043067]; sphingolipid biosynthetic process [GO:0030148]; sphingosine biosynthetic process [GO:0046512] GO:0000139; GO:0005509; GO:0005789; GO:0006954; GO:0008270; GO:0008284; GO:0016020; GO:0017040; GO:0030148; GO:0042552; GO:0043067; GO:0046512; GO:0046514; GO:0070774; GO:0071602; GO:0071633; GO:0102121 39716 XM_044319524.1 0 6 2 18 13 NA NA NA NA NA NA 39717 XM_044307590.1 0 15 36 10 0 NA NA NA NA NA NA 39718 XM_044307319.1 0 15 82 0 17 Q9Y3Q0 6.38e-50 N-acetylated-alpha-linked acidic dipeptidase 2 (EC 3.4.17.21) (Glutamate carboxypeptidase III) (GCPIII) (N-acetylated-alpha-linked acidic dipeptidase II) (NAALADase II) Homo sapiens (Human) proteolysis [GO:0006508] GO:0004180; GO:0004181; GO:0005886; GO:0006508; GO:0008236; GO:0008239; GO:0016020; GO:0016805; GO:0046872 39719 XM_044307319.1 0 15 82 0 17 Q9Y3Q0 6.38e-50 N-acetylated-alpha-linked acidic dipeptidase 2 (EC 3.4.17.21) (Glutamate carboxypeptidase III) (GCPIII) (N-acetylated-alpha-linked acidic dipeptidase II) (NAALADase II) Homo sapiens (Human) proteolysis [GO:0006508] GO:0004180; GO:0004181; GO:0005886; GO:0006508; GO:0008236; GO:0008239; GO:0016020; GO:0016805; GO:0046872 39720 XR_006397937.1 0 6 0 17 28 NA NA NA NA NA NA 39721 XM_029342317.2 434 176 75 35 83 P97292 1.34e-34 Histamine H2 receptor (H2R) (HH2R) (Gastric receptor I) Mus musculus (Mouse) chemical synaptic transmission [GO:0007268]; digestive tract development [GO:0048565]; epithelial cell morphogenesis [GO:0003382]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; gastric acid secretion [GO:0001696]; gastrin-induced gastric acid secretion [GO:0001698]; gland development [GO:0048732]; histamine-induced gastric acid secretion [GO:0001697]; memory [GO:0007613]; negative regulation of arachidonic acid secretion [GO:1900139]; positive regulation of vasoconstriction [GO:0045907]; regulation of synaptic plasticity [GO:0048167]; toxin transport [GO:1901998]; visual learning [GO:0008542] GO:0001696; GO:0001697; GO:0001698; GO:0003382; GO:0004969; GO:0004993; GO:0005886; GO:0007187; GO:0007268; GO:0007613; GO:0008542; GO:0016020; GO:0030425; GO:0030594; GO:0045202; GO:0045907; GO:0048167; GO:0048565; GO:0048732; GO:1900139; GO:1901363; GO:1901998 39722 XR_006393484.1 36 33 58 14 429 NA NA NA NA NA NA 39723 XM_044319025.1 0 0 0 8 6 Q9UHC6 3.48e-38 Contactin-associated protein-like 2 (Cell recognition molecule Caspr2) Homo sapiens (Human) adult behavior [GO:0030534]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell population proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; clustering of voltage-gated potassium channels [GO:0045163]; learning [GO:0007612]; limbic system development [GO:0021761]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuron recognition [GO:0008038]; positive regulation of gap junction assembly [GO:1903598]; protein localization to juxtaparanode region of axon [GO:0071205]; social behavior [GO:0035176]; striatum development [GO:0021756]; superior temporal gyrus development [GO:0071109]; thalamus development [GO:0021794]; transmission of nerve impulse [GO:0019226]; vocal learning [GO:0042297]; vocalization behavior [GO:0071625] GO:0005769; GO:0005794; GO:0007155; GO:0007420; GO:0007612; GO:0008038; GO:0008076; GO:0008283; GO:0009986; GO:0016020; GO:0019226; GO:0019899; GO:0021756; GO:0021761; GO:0021794; GO:0021987; GO:0030424; GO:0030425; GO:0030534; GO:0030673; GO:0031175; GO:0033010; GO:0035176; GO:0042297; GO:0043025; GO:0043204; GO:0044224; GO:0045163; GO:0048812; GO:0071109; GO:0071205; GO:0071625; GO:1903598 39724 XM_029349049.2 189 94 59 92 144 Q92113 1.6e-84 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Squalus acanthias (Spiny dogfish) steroid biosynthetic process [GO:0006694] GO:0004508; GO:0005506; GO:0006694; GO:0016020; GO:0020037; GO:0047442 39725 XM_044310767.1 163 24 20 147 712 O43854 2.85e-24 EGF-like repeat and discoidin I-like domain-containing protein 3 (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1) Homo sapiens (Human) cell adhesion [GO:0007155]; positive regulation of cell-substrate adhesion [GO:0010811] GO:0005178; GO:0005509; GO:0007155; GO:0010811; GO:0062023; GO:0070062; GO:1903561 39726 XM_044310767.1 163 24 20 147 712 O43854 3.03e-22 EGF-like repeat and discoidin I-like domain-containing protein 3 (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1) Homo sapiens (Human) cell adhesion [GO:0007155]; positive regulation of cell-substrate adhesion [GO:0010811] GO:0005178; GO:0005509; GO:0007155; GO:0010811; GO:0062023; GO:0070062; GO:1903561 39727 XM_029339109.2 0 0 168 525 0 Q3TZ87 1.23e-22 E3 ubiquitin-protein ligase MARCHF9 (EC 2.3.2.27) (Membrane-associated RING finger protein 9) (Membrane-associated RING-CH protein IX) (MARCH-IX) (RING-type E3 ubiquitin transferase MARCHF9) Mus musculus (Mouse) NA GO:0000139; GO:0004842; GO:0005765; GO:0005795; GO:0005802; GO:0008270 39728 XM_029335142.2 338 86 91 211 163 P54923 1.48e-134 ADP-ribosylhydrolase ARH1 (EC 3.2.2.19) (ADP-ribose-L-arginine cleaving enzyme) ([Protein ADP-ribosylarginine] hydrolase) (ADP-ribosylarginine hydrolase) Mus musculus (Mouse) protein de-ADP-ribosylation [GO:0051725]; protein modification process [GO:0036211] GO:0000287; GO:0003875; GO:0005615; GO:0005829; GO:0030955; GO:0036211; GO:0051725 39729 XM_044317489.1 774 0 0 0 406 Q13114 1.42e-90 TNF receptor-associated factor 3 (EC 2.3.2.27) (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein 1) (LAP1) (RING-type E3 ubiquitin transferase TRAF3) Homo sapiens (Human) apoptotic process [GO:0006915]; defense response to virus [GO:0051607]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of JNK cascade [GO:0046330]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of cytokine production [GO:0001817]; regulation of defense response to virus [GO:0050688]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of interferon-beta production [GO:0032648]; regulation of proteolysis [GO:0030162]; signal transduction [GO:0007165]; Toll signaling pathway [GO:0008063]; toll-like receptor signaling pathway [GO:0002224]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; type I interferon-mediated signaling pathway [GO:0060337] GO:0000151; GO:0001817; GO:0002224; GO:0004842; GO:0005164; GO:0005739; GO:0005768; GO:0005829; GO:0006915; GO:0007165; GO:0008063; GO:0008270; GO:0009898; GO:0019901; GO:0019903; GO:0030162; GO:0031625; GO:0031996; GO:0032088; GO:0032648; GO:0033209; GO:0035631; GO:0035666; GO:0042802; GO:0042981; GO:0043122; GO:0046330; GO:0050688; GO:0051607; GO:0060337; GO:0070534; GO:1902554 39730 XM_029351107.2 1 0 17 53 2 NA NA NA NA NA NA 39731 XM_029356790.2 751 771 545 625 527 Q99542 3.18e-47 Matrix metalloproteinase-19 (MMP-19) (EC 3.4.24.-) (Matrix metalloproteinase RASI) (Matrix metalloproteinase-18) (MMP-18) Homo sapiens (Human) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; luteolysis [GO:0001554]; ovarian follicle development [GO:0001541]; ovulation from ovarian follicle [GO:0001542]; proteolysis [GO:0006508]; response to cAMP [GO:0051591]; response to hormone [GO:0009725] GO:0001525; GO:0001541; GO:0001542; GO:0001554; GO:0004222; GO:0004252; GO:0005576; GO:0005615; GO:0006508; GO:0008270; GO:0009725; GO:0022617; GO:0030154; GO:0030198; GO:0030574; GO:0031012; GO:0051591 39732 XR_003824112.2 318 329 246 611 1289 NA NA NA NA NA NA 39733 XM_044327280.1 0 6 2 1 17 NA NA NA NA NA NA 39734 XM_029348508.2 27 1 41 3 136 NA NA NA NA NA NA 39735 XR_006395451.1 13 29 36 3 14 P26152 3e-55 Neuronal acetylcholine receptor subunit alpha-5 Gallus gallus (Chicken) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; response to nicotine [GO:0035094]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271] GO:0004888; GO:0005231; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0007271; GO:0022848; GO:0030594; GO:0034220; GO:0035094; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051899; GO:1904315 39736 XM_044311863.1 4264 4715 2268 3933 1595 P46436 4.85e-23 Glutathione S-transferase 1 (EC 2.5.1.18) (GST class-sigma) Ascaris suum (Pig roundworm) (Ascaris lumbricoides) cellular oxidant detoxification [GO:0098869] GO:0004364; GO:0004602; GO:0005737; GO:0005903; GO:0098869 39737 XR_006393225.1 4 0 0 6 14 NA NA NA NA NA NA 39738 XM_044322424.1 120 18 27 112 46 NA NA NA NA NA NA 39739 XM_029336491.2 176 107 162 232 421 P20585 0 DNA mismatch repair protein Msh3 (hMSH3) (Divergent upstream protein) (DUP) (Mismatch repair protein 1) (MRP1) Homo sapiens (Human) DNA repair [GO:0006281]; maintenance of DNA repeat elements [GO:0043570]; mismatch repair [GO:0006298]; mitotic recombination [GO:0006312]; negative regulation of DNA recombination [GO:0045910]; positive regulation of helicase activity [GO:0051096]; somatic recombination of immunoglobulin gene segments [GO:0016447] GO:0003690; GO:0005524; GO:0005634; GO:0005654; GO:0006281; GO:0006298; GO:0006312; GO:0016020; GO:0016447; GO:0019899; GO:0030983; GO:0032302; GO:0043570; GO:0045910; GO:0051096; GO:0140664 39740 XM_044313138.1 479 386 338 708 716 Q9VCA8 8.71e-43 Ankyrin repeat and KH domain-containing protein mask (Multiple ankyrin repeat single KH domain-containing protein) Drosophila melanogaster (Fruit fly) compound eye photoreceptor cell differentiation [GO:0001751]; dorsal appendage formation [GO:0046843]; flight [GO:0060361]; mitochondrion organization [GO:0007005]; negative regulation of autophagy of mitochondrion [GO:1903147]; negative regulation of establishment of blood-brain barrier [GO:0090212]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of sevenless signaling pathway [GO:0045874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; sarcomere organization [GO:0045214]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing, spreading of cells [GO:0044319]; wound healing, spreading of epidermal cells [GO:0035313] GO:0001751; GO:0003723; GO:0005634; GO:0005737; GO:0005829; GO:0007005; GO:0007169; GO:0019901; GO:0030018; GO:0031430; GO:0035313; GO:0044319; GO:0045214; GO:0045874; GO:0045944; GO:0046427; GO:0046843; GO:0060361; GO:0090212; GO:0090575; GO:1903147 39741 XM_044313138.1 479 386 338 708 716 Q9VCA8 2.38e-30 Ankyrin repeat and KH domain-containing protein mask (Multiple ankyrin repeat single KH domain-containing protein) Drosophila melanogaster (Fruit fly) compound eye photoreceptor cell differentiation [GO:0001751]; dorsal appendage formation [GO:0046843]; flight [GO:0060361]; mitochondrion organization [GO:0007005]; negative regulation of autophagy of mitochondrion [GO:1903147]; negative regulation of establishment of blood-brain barrier [GO:0090212]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of sevenless signaling pathway [GO:0045874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; sarcomere organization [GO:0045214]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing, spreading of cells [GO:0044319]; wound healing, spreading of epidermal cells [GO:0035313] GO:0001751; GO:0003723; GO:0005634; GO:0005737; GO:0005829; GO:0007005; GO:0007169; GO:0019901; GO:0030018; GO:0031430; GO:0035313; GO:0044319; GO:0045214; GO:0045874; GO:0045944; GO:0046427; GO:0046843; GO:0060361; GO:0090212; GO:0090575; GO:1903147 39742 XM_044313138.1 479 386 338 708 716 Q9VCA8 1.27e-26 Ankyrin repeat and KH domain-containing protein mask (Multiple ankyrin repeat single KH domain-containing protein) Drosophila melanogaster (Fruit fly) compound eye photoreceptor cell differentiation [GO:0001751]; dorsal appendage formation [GO:0046843]; flight [GO:0060361]; mitochondrion organization [GO:0007005]; negative regulation of autophagy of mitochondrion [GO:1903147]; negative regulation of establishment of blood-brain barrier [GO:0090212]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of sevenless signaling pathway [GO:0045874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; sarcomere organization [GO:0045214]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing, spreading of cells [GO:0044319]; wound healing, spreading of epidermal cells [GO:0035313] GO:0001751; GO:0003723; GO:0005634; GO:0005737; GO:0005829; GO:0007005; GO:0007169; GO:0019901; GO:0030018; GO:0031430; GO:0035313; GO:0044319; GO:0045214; GO:0045874; GO:0045944; GO:0046427; GO:0046843; GO:0060361; GO:0090212; GO:0090575; GO:1903147 39743 XM_044313138.1 479 386 338 708 716 Q9VCA8 2.92e-26 Ankyrin repeat and KH domain-containing protein mask (Multiple ankyrin repeat single KH domain-containing protein) Drosophila melanogaster (Fruit fly) compound eye photoreceptor cell differentiation [GO:0001751]; dorsal appendage formation [GO:0046843]; flight [GO:0060361]; mitochondrion organization [GO:0007005]; negative regulation of autophagy of mitochondrion [GO:1903147]; negative regulation of establishment of blood-brain barrier [GO:0090212]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of sevenless signaling pathway [GO:0045874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; sarcomere organization [GO:0045214]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing, spreading of cells [GO:0044319]; wound healing, spreading of epidermal cells [GO:0035313] GO:0001751; GO:0003723; GO:0005634; GO:0005737; GO:0005829; GO:0007005; GO:0007169; GO:0019901; GO:0030018; GO:0031430; GO:0035313; GO:0044319; GO:0045214; GO:0045874; GO:0045944; GO:0046427; GO:0046843; GO:0060361; GO:0090212; GO:0090575; GO:1903147 39744 XM_044313138.1 479 386 338 708 716 Q9VCA8 7.24e-26 Ankyrin repeat and KH domain-containing protein mask (Multiple ankyrin repeat single KH domain-containing protein) Drosophila melanogaster (Fruit fly) compound eye photoreceptor cell differentiation [GO:0001751]; dorsal appendage formation [GO:0046843]; flight [GO:0060361]; mitochondrion organization [GO:0007005]; negative regulation of autophagy of mitochondrion [GO:1903147]; negative regulation of establishment of blood-brain barrier [GO:0090212]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of sevenless signaling pathway [GO:0045874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; sarcomere organization [GO:0045214]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing, spreading of cells [GO:0044319]; wound healing, spreading of epidermal cells [GO:0035313] GO:0001751; GO:0003723; GO:0005634; GO:0005737; GO:0005829; GO:0007005; GO:0007169; GO:0019901; GO:0030018; GO:0031430; GO:0035313; GO:0044319; GO:0045214; GO:0045874; GO:0045944; GO:0046427; GO:0046843; GO:0060361; GO:0090212; GO:0090575; GO:1903147 39745 XM_044313138.1 479 386 338 708 716 Q9VCA8 3.6e-21 Ankyrin repeat and KH domain-containing protein mask (Multiple ankyrin repeat single KH domain-containing protein) Drosophila melanogaster (Fruit fly) compound eye photoreceptor cell differentiation [GO:0001751]; dorsal appendage formation [GO:0046843]; flight [GO:0060361]; mitochondrion organization [GO:0007005]; negative regulation of autophagy of mitochondrion [GO:1903147]; negative regulation of establishment of blood-brain barrier [GO:0090212]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of sevenless signaling pathway [GO:0045874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; sarcomere organization [GO:0045214]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing, spreading of cells [GO:0044319]; wound healing, spreading of epidermal cells [GO:0035313] GO:0001751; GO:0003723; GO:0005634; GO:0005737; GO:0005829; GO:0007005; GO:0007169; GO:0019901; GO:0030018; GO:0031430; GO:0035313; GO:0044319; GO:0045214; GO:0045874; GO:0045944; GO:0046427; GO:0046843; GO:0060361; GO:0090212; GO:0090575; GO:1903147 39746 XM_044326884.1 4 0 11 3 1 NA NA NA NA NA NA 39747 XM_029330308.2 350 711 388 449 420 Q62384 1.11e-163 Zinc finger protein ZPR1 (Zinc finger protein 259) Mus musculus (Mouse) apoptotic process involved in development [GO:1902742]; axon development [GO:0061564]; Cajal body organization [GO:0030576]; cell population proliferation [GO:0008283]; cellular response to epidermal growth factor stimulus [GO:0071364]; DNA endoreduplication [GO:0042023]; inner cell mass cell proliferation [GO:0001833]; microtubule cytoskeleton organization [GO:0000226]; mRNA processing [GO:0006397]; negative regulation of motor neuron apoptotic process [GO:2000672]; positive regulation of cell cycle [GO:0045787]; positive regulation of gene expression [GO:0010628]; positive regulation of growth [GO:0045927]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of RNA splicing [GO:0033120]; positive regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0071931]; pre-mRNA catabolic process [GO:1990261]; regulation of myelination [GO:0031641]; RNA splicing [GO:0008380]; spinal cord development [GO:0021510]; trophectodermal cell proliferation [GO:0001834] GO:0000226; GO:0001833; GO:0001834; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0006397; GO:0008270; GO:0008283; GO:0008380; GO:0010628; GO:0015030; GO:0021510; GO:0030424; GO:0030426; GO:0030576; GO:0030971; GO:0031369; GO:0031641; GO:0033120; GO:0042023; GO:0042307; GO:0043025; GO:0043204; GO:0045787; GO:0045927; GO:0048471; GO:0061564; GO:0071364; GO:0071931; GO:0097504; GO:1902742; GO:1990261; GO:2000672 39748 XM_029351556.2 37 13 9 7 54 P43141 1.47e-21 Beta-4C adrenergic receptor (Beta-4C adrenoreceptor) (Beta-4C adrenoceptor) Meleagris gallopavo (Wild turkey) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; positive regulation of heart contraction [GO:0045823] GO:0004940; GO:0005886; GO:0007189; GO:0045823 39749 XM_044325021.1 367 169 340 353 312 Q5ZIJ9 4.4e-149 E3 ubiquitin-protein ligase MIB2 (EC 2.3.2.27) (Mind bomb homolog 2) (RING-type E3 ubiquitin transferase MIB2) Gallus gallus (Chicken) Notch signaling pathway [GO:0007219]; protein ubiquitination [GO:0016567] GO:0004842; GO:0005737; GO:0007219; GO:0008270; GO:0016567 39750 XM_029353528.2 540 272 295 361 766 Q9CQS5 6.79e-163 Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2) Mus musculus (Mouse) maturation of SSU-rRNA [GO:0030490]; positive regulation of ribosomal small subunit export from nucleus [GO:2000208]; positive regulation of rRNA processing [GO:2000234]; protein autophosphorylation [GO:0046777]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; ribosomal small subunit biogenesis [GO:0042274] GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0030071; GO:0030490; GO:0030688; GO:0042274; GO:0046777; GO:0046872; GO:0106310; GO:2000208; GO:2000234 39751 XM_044309819.1 7 0 4 40 32 P10079 4.43e-104 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 39752 XM_044309819.1 7 0 4 40 32 P10079 5.83e-99 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 39753 XM_044309819.1 7 0 4 40 32 P10079 3.03e-96 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 39754 XM_044309819.1 7 0 4 40 32 P10079 6.08e-96 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 39755 XM_044309819.1 7 0 4 40 32 P10079 7e-95 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 39756 XM_044309819.1 7 0 4 40 32 P10079 7.07e-95 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 39757 XM_044309819.1 7 0 4 40 32 P10079 1.96e-94 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 39758 XM_044309819.1 7 0 4 40 32 P10079 2.56e-94 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 39759 XM_044309819.1 7 0 4 40 32 P10079 1.13e-91 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 39760 XM_044309819.1 7 0 4 40 32 P10079 3.72e-90 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 39761 XM_044309819.1 7 0 4 40 32 P10079 3.8e-24 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 39762 XM_044325119.1 1 1 5 9 0 NA NA NA NA NA NA 39763 XM_044312067.1 17 10 52 4 24 NA NA NA NA NA NA 39764 XM_044315115.1 4 0 6 5 25 NA NA NA NA NA NA 39765 XR_003823458.2 1169 1162 504 1243 841 NA NA NA NA NA NA 39766 XM_044320099.1 724 20 24 52 433 NA NA NA NA NA NA 39767 XR_006397107.1 0 0 0 8 7 NA NA NA NA NA NA 39768 XM_044319974.1 24 389 65 23 351 NA NA NA NA NA NA 39769 XM_044322990.1 15 18 27 11 2 Q5R9I3 6.43e-26 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cellular response to glucose starvation [GO:0042149]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; protein phosphorylation [GO:0006468] GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005930; GO:0006468; GO:0016236; GO:0035032; GO:0042149; GO:0045324; GO:0106310 39770 XR_006395056.1 120986 118115 57790 135974 62395 NA NA NA NA NA NA 39771 XM_029349532.2 0 64 0 0 0 A7SXG9 5.06e-38 Nematocyst expressed protein 8 (NEP-8) (NEP8) Nematostella vectensis (Starlet sea anemone) NA GO:0005576; GO:0042151; GO:0090729 39772 XM_044324341.1 8 29 8 39 0 NA NA NA NA NA NA 39773 XR_006396652.1 0 0 0 9 5 NA NA NA NA NA NA 39774 XM_029339302.2 2376 3183 1917 2346 1422 P52504 3.66e-36 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (Complex I-13kD-A) (CI-13kD-A) (NADH-ubiquinone oxidoreductase 13 kDa-A subunit) Rattus norvegicus (Rat) circulatory system development [GO:0072359]; fatty acid metabolic process [GO:0006631]; kidney development [GO:0001822]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrial respiratory chain complex I assembly [GO:0032981]; mitochondrion morphogenesis [GO:0070584]; multicellular organism aging [GO:0010259]; multicellular organism growth [GO:0035264]; muscle contraction [GO:0006936]; reproductive system development [GO:0061458]; respiratory electron transport chain [GO:0022904] GO:0001822; GO:0005739; GO:0005743; GO:0005747; GO:0006120; GO:0006631; GO:0006936; GO:0010259; GO:0022904; GO:0032981; GO:0035264; GO:0061458; GO:0070584; GO:0072359 39775 XM_044310428.1 17 0 74 0 76 NA NA NA NA NA NA 39776 XM_029338360.2 486 121 209 732 432 Q96F81 0 Protein dispatched homolog 1 Homo sapiens (Human) determination of left/right symmetry [GO:0007368]; diaphragm development [GO:0060539]; dorsal/ventral pattern formation [GO:0009953]; embryonic pattern specification [GO:0009880]; patched ligand maturation [GO:0007225]; peptide transport [GO:0015833]; protein homotrimerization [GO:0070207]; regulation of protein secretion [GO:0050708]; smoothened signaling pathway [GO:0007224]; transmembrane transport [GO:0055085] GO:0007224; GO:0007225; GO:0007368; GO:0009880; GO:0009953; GO:0015833; GO:0016020; GO:0016323; GO:0022857; GO:0050708; GO:0055085; GO:0060539; GO:0070207; GO:1904680 39777 XM_029336999.2 319 270 271 332 401 Q5RHR6 0 Protein broad-minded (TBC1 domain family member 32) Danio rerio (Zebrafish) (Brachydanio rerio) axoneme assembly [GO:0035082]; cilium assembly [GO:0060271]; non-motile cilium assembly [GO:1905515] GO:0005737; GO:0005929; GO:0035082; GO:0060271; GO:1905515 39778 XR_006395143.1 49 14 23 57 89 NA NA NA NA NA NA 39779 XM_029341601.2 435 697 419 294 627 Q8K2X3 1.09e-29 CST complex subunit STN1 (Alpha-accessory factor of 44 kDa) (AAF-44) (AAF44) (Oligonucleotide/oligosaccharide-binding fold-containing protein 1) (Suppressor of cdc thirteen homolog) Mus musculus (Mouse) negative regulation of telomere maintenance via telomerase [GO:0032211]; positive regulation of DNA replication [GO:0045740]; telomere capping [GO:0016233]; telomere maintenance [GO:0000723]; telomere maintenance via telomere lengthening [GO:0010833] GO:0000723; GO:0000781; GO:0001650; GO:0003697; GO:0005634; GO:0005654; GO:0010833; GO:0016233; GO:0032211; GO:0042162; GO:0043047; GO:0043231; GO:0045111; GO:0045740; GO:1990879 39780 XM_029328706.2 21 20 127 224 201 NA NA NA NA NA NA 39781 XM_029352623.2 0 5 44 62 0 P49117 9.44e-35 Nuclear receptor subfamily 2 group C member 2 (Orphan nuclear receptor TAK1) (Orphan nuclear receptor TR4) (Testicular receptor 4) Mus musculus (Mouse) anatomical structure development [GO:0048856]; cell differentiation [GO:0030154]; cerebellum development [GO:0021549]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; meiotic cell cycle [GO:0051321]; negative regulation of transcription by RNA polymerase II [GO:0000122]; p38MAPK cascade [GO:0038066]; positive regulation of behavior [GO:0048520]; positive regulation of embryonic development [GO:0040019]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283] GO:0000122; GO:0000977; GO:0000978; GO:0001228; GO:0003700; GO:0004879; GO:0005654; GO:0006357; GO:0007283; GO:0008270; GO:0021549; GO:0030154; GO:0031663; GO:0038066; GO:0040019; GO:0043565; GO:0045663; GO:0045944; GO:0048520; GO:0048856; GO:0051321; GO:1990837 39782 XM_029327872.2 0 0 3 0 14 NA NA NA NA NA NA 39783 XM_029355288.2 0 0 0 0 42 Q9WUA2 0 Phenylalanine--tRNA ligase beta subunit (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase beta subunit) (PheRS) Mus musculus (Mouse) phenylalanyl-tRNA aminoacylation [GO:0006432]; protein heterotetramerization [GO:0051290] GO:0000287; GO:0003723; GO:0004826; GO:0005524; GO:0006432; GO:0009328; GO:0051290 39784 XM_029353381.2 9 0 7 1 16 P58308 9.57e-24 Orexin receptor type 2 (Ox-2-R) (Ox2-R) (Ox2R) (Hypocretin receptor type 2) Mus musculus (Mouse) circadian sleep/wake cycle process [GO:0022410]; feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; locomotion [GO:0040011]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; regulation of circadian sleep/wake cycle, wakefulness [GO:0010840]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0004930; GO:0005886; GO:0007186; GO:0007200; GO:0007218; GO:0007631; GO:0010840; GO:0016499; GO:0017046; GO:0022410; GO:0040011; GO:0051480 39785 XM_029356417.2 15 0 0 19 0 Q5S1U6 6.43e-92 Interferon-related developmental regulator 1 Sus scrofa (Pig) cell differentiation [GO:0030154] GO:0005634; GO:0030154 39786 XM_029337192.2 0 0 10 0 23 NA NA NA NA NA NA 39787 XM_044319089.1 197 170 0 34 137 NA NA NA NA NA NA 39788 XM_029327369.2 276 170 172 296 390 NA NA NA NA NA NA 39789 XM_029353410.2 3 2 4 7 13 NA NA NA NA NA NA 39790 XM_029353765.2 2652 2938 1056 6944 3888 NA NA NA NA NA NA 39791 XR_003825773.2 49 19 44 31 55 NA NA NA NA NA NA 39792 XM_044323833.1 405 303 0 767 674 Q4LDE5 1.01e-161 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 39793 XM_044323833.1 405 303 0 767 674 Q4LDE5 1.95e-158 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 39794 XM_044323833.1 405 303 0 767 674 Q4LDE5 1.97e-158 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 39795 XM_044323833.1 405 303 0 767 674 Q4LDE5 2.48e-157 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 39796 XM_044323833.1 405 303 0 767 674 Q4LDE5 6.62e-148 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 39797 XM_029332595.2 192 74 79 67 100 E7EYQ9 3.09e-21 Transmembrane protein 216 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension involved in gastrulation [GO:0060027]; non-motile cilium assembly [GO:1905515] GO:0005737; GO:0005856; GO:0016020; GO:0035869; GO:0060027; GO:0060271; GO:1905515 39798 XM_044326265.1 47 77 35 94 39 NA NA NA NA NA NA 39799 XM_029338976.2 56 37 20 49 83 NA NA NA NA NA NA 39800 XM_029323988.2 1059 683 587 899 933 Q9DBU0 0 Transmembrane 9 superfamily member 1 Mus musculus (Mouse) autophagy [GO:0006914]; protein localization to membrane [GO:0072657] GO:0000421; GO:0005765; GO:0006914; GO:0016020; GO:0031410; GO:0072657 39801 XM_044318219.1 62 0 0 4 41 NA NA NA NA NA NA 39802 XM_029327748.2 13 0 28 0 0 P08510 2.67e-106 Potassium voltage-gated channel protein Shaker (Protein minisleep) Drosophila melanogaster (Fruit fly) action potential [GO:0001508]; axon extension [GO:0048675]; behavioral response to ether [GO:0048150]; cellular response to dopamine [GO:1903351]; courtship behavior [GO:0007619]; detection of visible light [GO:0009584]; larval locomotory behavior [GO:0008345]; learning or memory [GO:0007611]; mating behavior, sex discrimination [GO:0048047]; positive regulation of circadian sleep/wake cycle, sleep [GO:0045938]; positive regulation of membrane potential [GO:0045838]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; proboscis extension reflex [GO:0007637]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; regulation of ion transmembrane transport [GO:0034765]; regulation of synaptic activity [GO:0060025]; sensory perception of taste [GO:0050909]; sleep [GO:0030431] GO:0001508; GO:0005249; GO:0005251; GO:0006813; GO:0007611; GO:0007619; GO:0007637; GO:0008076; GO:0008345; GO:0009584; GO:0016020; GO:0022843; GO:0030431; GO:0034765; GO:0045187; GO:0045838; GO:0045938; GO:0048047; GO:0048150; GO:0048675; GO:0050909; GO:0051260; GO:0060025; GO:0071805; GO:1903351 39803 XM_029324254.2 15 12 0 30 2 P0CT39 3.27e-86 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 39804 XM_044313791.1 8 0 29 4 61 NA NA NA NA NA NA 39805 XM_029344970.2 749 772 293 1056 805 P50637 2.16e-42 Translocator protein (Mitochondrial benzodiazepine receptor) (PKBS) (Peripheral-type benzodiazepine receptor) (PBR) Mus musculus (Mouse) adrenal gland development [GO:0030325]; aging [GO:0007568]; behavioral response to pain [GO:0048266]; cellular hypotonic response [GO:0071476]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to zinc ion [GO:0071294]; chloride transport [GO:0006821]; cholesterol homeostasis [GO:0042632]; contact inhibition [GO:0060242]; establishment of protein localization to mitochondrion [GO:0072655]; glial cell migration [GO:0008347]; ion transport [GO:0006811]; lipid transport [GO:0006869]; maintenance of protein location in mitochondrion [GO:0072656]; negative regulation of ATP metabolic process [GO:1903579]; negative regulation of autophagy of mitochondrion [GO:1903147]; negative regulation of corticosterone secretion [GO:2000853]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of mitochondrion organization [GO:0010823]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of tumor necrosis factor production [GO:0032720]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of apoptotic process [GO:0043065]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of necrotic cell death [GO:0010940]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; regulation of steroid biosynthetic process [GO:0050810]; response to acetylcholine [GO:1905144]; response to manganese ion [GO:0010042]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]; response to vitamin B1 [GO:0010266]; response to xenobiotic stimulus [GO:0009410]; steroid biosynthetic process [GO:0006694] GO:0005497; GO:0005739; GO:0005741; GO:0005783; GO:0005829; GO:0006694; GO:0006811; GO:0006821; GO:0006869; GO:0007568; GO:0008347; GO:0008503; GO:0009410; GO:0010042; GO:0010266; GO:0010823; GO:0010940; GO:0014012; GO:0015485; GO:0016020; GO:0030325; GO:0031397; GO:0032570; GO:0032720; GO:0033574; GO:0042632; GO:0043065; GO:0043231; GO:0044325; GO:0045019; GO:0048266; GO:0050810; GO:0051901; GO:0051928; GO:0060242; GO:0060252; GO:0060253; GO:0071222; GO:0071294; GO:0071476; GO:0072655; GO:0072656; GO:1903147; GO:1903579; GO:1905144; GO:2000379; GO:2000853 39806 XM_044311799.1 77 106 0 1 65 NA NA NA NA NA NA 39807 XM_029350512.2 857 825 465 916 953 Q7ZXF5 2.87e-153 Fatty acyl-CoA reductase 1 (EC 1.2.1.84) Xenopus laevis (African clawed frog) ether lipid biosynthetic process [GO:0008611]; wax biosynthetic process [GO:0010025] GO:0005778; GO:0008611; GO:0010025; GO:0080019; GO:0102965 39808 XM_029327395.2 483 546 170 731 1027 A1A5X5 2.15e-29 Adipolin (Adipose-derived insulin-sensitizing factor) (Complement C1q tumor necrosis factor-related protein 12) Danio rerio (Zebrafish) (Brachydanio rerio) regulation of glucose import [GO:0046324]; Wnt signaling pathway [GO:0016055] GO:0005179; GO:0005576; GO:0005615; GO:0016055; GO:0046324 39809 XM_029337407.2 0 41 0 28 4 Q9BS34 7.47e-30 Zinc finger protein 670 Homo sapiens (Human) cellular lipid metabolic process [GO:0044255]; lipid metabolic process [GO:0006629]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0006629; GO:0044255; GO:0046872 39810 XM_029337407.2 0 41 0 28 4 Q9BS34 3.97e-28 Zinc finger protein 670 Homo sapiens (Human) cellular lipid metabolic process [GO:0044255]; lipid metabolic process [GO:0006629]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0006629; GO:0044255; GO:0046872 39811 XM_029337407.2 0 41 0 28 4 Q9BS34 1.88e-25 Zinc finger protein 670 Homo sapiens (Human) cellular lipid metabolic process [GO:0044255]; lipid metabolic process [GO:0006629]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0006629; GO:0044255; GO:0046872 39812 XM_029337407.2 0 41 0 28 4 Q9BS34 2.35e-25 Zinc finger protein 670 Homo sapiens (Human) cellular lipid metabolic process [GO:0044255]; lipid metabolic process [GO:0006629]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0006629; GO:0044255; GO:0046872 39813 XR_006397168.1 2608 2234 1542 1448 992 Q8AVU4 5.71e-25 Transcription factor HES-1-B (Hairy and enhancer of split 1-B) Xenopus laevis (African clawed frog) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of muscle organ development [GO:0048635]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219] GO:0000122; GO:0003677; GO:0005634; GO:0007219; GO:0043425; GO:0045892; GO:0046982; GO:0048635 39814 XM_044310507.1 404 1719 147 419 350 Q7RTR2 6.28e-45 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 39815 XM_044310507.1 404 1719 147 419 350 Q7RTR2 1.73e-39 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 39816 XM_044310507.1 404 1719 147 419 350 Q7RTR2 1.73e-39 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 39817 XM_044310507.1 404 1719 147 419 350 Q7RTR2 1.05e-37 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 39818 XM_044310507.1 404 1719 147 419 350 Q7RTR2 3.97e-37 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 39819 XM_044310507.1 404 1719 147 419 350 Q7RTR2 3.96e-36 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 39820 XM_044310507.1 404 1719 147 419 350 Q7RTR2 1.29e-32 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 39821 XM_029343586.2 118 98 76 56 103 Q8N5P1 1.54e-29 Zinc finger CCCH domain-containing protein 8 Homo sapiens (Human) apoptotic process [GO:0006915]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of T cell differentiation in thymus [GO:0033085]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase III [GO:0045945]; response to antibiotic [GO:0046677]; snRNA transcription by RNA polymerase II [GO:0042795]; snRNA transcription by RNA polymerase III [GO:0042796]; T cell homeostasis [GO:0043029] GO:0000785; GO:0000791; GO:0001162; GO:0001227; GO:0003723; GO:0005634; GO:0005654; GO:0006915; GO:0008023; GO:0015030; GO:0016604; GO:0033085; GO:0035363; GO:0042795; GO:0042796; GO:0043029; GO:0045892; GO:0045945; GO:0046677; GO:0046872; GO:0070245 39822 XM_044322421.1 154 57 90 80 186 Q91VU7 3.17e-157 Pseudouridylate synthase 7 homolog (EC 5.4.99.-) Mus musculus (Mouse) mRNA processing [GO:0006397]; mRNA pseudouridine synthesis [GO:1990481]; negative regulation of translation [GO:0017148]; pseudouridine synthesis [GO:0001522]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mesoderm development [GO:2000380]; RNA splicing [GO:0008380]; tRNA pseudouridine synthesis [GO:0031119] GO:0001522; GO:0003723; GO:0005634; GO:0006397; GO:0008380; GO:0009982; GO:0017148; GO:0019899; GO:0031119; GO:1902036; GO:1990481; GO:2000380 39823 XR_006397825.1 0 602 238 422 201 NA NA NA NA NA NA 39824 XM_044323624.1 466 590 117 939 151 NA NA NA NA NA NA 39825 XM_044311608.1 0 0 0 4 16 O60290 4.27e-30 Zinc finger protein 862 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006355; GO:0046872; GO:0046983 39826 XM_044324284.1 2364 1645 1316 2305 2051 NA NA NA NA NA NA 39827 XM_044307789.1 75 130 45 0 262 NA NA NA NA NA NA 39828 XM_044315236.1 29 32 20 0 15 NA NA NA NA NA NA 39829 XM_044307281.1 227 246 0 52 87 Q1LZH1 1e-39 Mitochondrial amidoxime reducing component 2 (mARC2) (EC 1.7.-.-) (Molybdenum cofactor sulfurase C-terminal domain-containing protein 2) (MOSC domain-containing protein 2) (Moco sulfurase C-terminal domain-containing protein 2) Bos taurus (Bovine) cellular detoxification of nitrogen compound [GO:0070458]; nitrate metabolic process [GO:0042126]; nitric oxide biosynthetic process [GO:0006809] GO:0005741; GO:0005777; GO:0006809; GO:0008940; GO:0030151; GO:0030170; GO:0042126; GO:0043546; GO:0070458; GO:0098809 39830 XM_044326088.1 207 161 159 165 271 NA NA NA NA NA NA 39831 XM_029328001.2 0 0 0 0 128 Q7RTR2 2.12e-72 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 39832 XM_029328001.2 0 0 0 0 128 Q7RTR2 7.66e-68 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 39833 XM_029328001.2 0 0 0 0 128 Q7RTR2 9.87e-67 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 39834 XM_029328001.2 0 0 0 0 128 Q7RTR2 1.29e-64 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 39835 XM_029328001.2 0 0 0 0 128 Q7RTR2 1.37e-60 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 39836 XM_029328001.2 0 0 0 0 128 Q7RTR2 3.28e-58 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 39837 XM_044311138.1 9 0 1 2 5 NA NA NA NA NA NA 39838 XM_044309989.1 281 184 157 193 336 O60282 0 Kinesin heavy chain isoform 5C (EC 3.6.4.-) (Kinesin heavy chain neuron-specific 2) (Kinesin-1) Homo sapiens (Human) anterograde axonal protein transport [GO:0099641]; anterograde dendritic transport of neurotransmitter receptor complex [GO:0098971]; axon guidance [GO:0007411]; cytoskeleton-dependent intracellular transport [GO:0030705]; microtubule-based movement [GO:0007018]; motor neuron axon guidance [GO:0008045]; mRNA transport [GO:0051028]; organelle organization [GO:0006996]; synaptic vesicle transport [GO:0048489] GO:0003777; GO:0005524; GO:0005871; GO:0005874; GO:0006996; GO:0007018; GO:0007411; GO:0008017; GO:0008045; GO:0008574; GO:0016887; GO:0030705; GO:0032839; GO:0035253; GO:0043025; GO:0044295; GO:0048489; GO:0051028; GO:0098971; GO:0099641; GO:0150034; GO:1904115 39839 XM_044319151.1 28 64 38 118 104 Q6AZB8 1.1e-26 Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0004518; GO:0005634; GO:0005737; GO:0046872 39840 XM_029326533.2 68 5 33 0 0 Q69Z28 5.21e-158 A disintegrin and metalloproteinase with thrombospondin motifs 16 (ADAM-TS 16) (ADAM-TS16) (ADAMTS-16) (EC 3.4.24.-) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; extracellular matrix organization [GO:0030198]; male gamete generation [GO:0048232]; proteolysis [GO:0006508]; regulation of cilium assembly [GO:1902017]; regulation of systemic arterial blood pressure [GO:0003073] GO:0001658; GO:0003073; GO:0004222; GO:0005576; GO:0006508; GO:0030198; GO:0031012; GO:0046872; GO:0048232; GO:1902017 39841 XM_044324507.1 160 69 181 465 289 NA NA NA NA NA NA 39842 XR_006395880.1 503 514 253 419 694 NA NA NA NA NA NA 39843 XM_029354552.2 575 515 211 374 246 NA NA NA NA NA NA 39844 XM_029325466.2 8 101 81 78 111 NA NA NA NA NA NA 39845 XM_044327182.1 140 1052 904 3260 542 NA NA NA NA NA NA 39846 XM_029334417.2 593 340 1499 538 217 Q6DKN2 5.95e-34 Homeobox protein OTX2-B (xOTX2-B) (Orthodenticle 2-B) (Orthodenticle-A-like protein B) Xenopus laevis (African clawed frog) NA GO:0000981; GO:0003677; GO:0005634 39847 XM_029356533.2 856 563 333 458 429 Q5RBL0 5e-89 Protein YIPF1 (YIP1 family member 1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) vesicle-mediated transport [GO:0016192] GO:0000138; GO:0005797; GO:0005802; GO:0016192; GO:0031267; GO:0031902 39848 XM_044326176.1 1 0 25 11 20 Q8I7P9 3.65e-53 Retrovirus-related Pol polyprotein from transposon opus [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508]; transposition, DNA-mediated [GO:0006313] GO:0003676; GO:0003887; GO:0003964; GO:0004519; GO:0005634; GO:0006313; GO:0006508; GO:0008233; GO:0015074; GO:0042575 39849 XM_044315054.1 161 137 48 278 171 NA NA NA NA NA NA 39850 XM_044317337.1 696 384 1039 1237 1421 Q4LDE5 7.11e-149 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 39851 XM_044317337.1 696 384 1039 1237 1421 Q4LDE5 2.37e-143 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 39852 XM_044317337.1 696 384 1039 1237 1421 Q4LDE5 3.75e-138 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 39853 XM_044317337.1 696 384 1039 1237 1421 Q4LDE5 8.88e-134 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 39854 XM_044317337.1 696 384 1039 1237 1421 Q4LDE5 1.79e-131 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 39855 XM_044317337.1 696 384 1039 1237 1421 Q4LDE5 1.41e-128 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 39856 XM_044317337.1 696 384 1039 1237 1421 Q4LDE5 3.39e-128 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 39857 XM_044317337.1 696 384 1039 1237 1421 Q4LDE5 4.14e-128 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 39858 XM_044317337.1 696 384 1039 1237 1421 Q4LDE5 9.42e-122 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 39859 XM_044317337.1 696 384 1039 1237 1421 Q4LDE5 8.81e-120 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 39860 XM_044317337.1 696 384 1039 1237 1421 Q4LDE5 2.91e-108 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 39861 XM_044317337.1 696 384 1039 1237 1421 Q4LDE5 1.75e-89 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 39862 XM_044317337.1 696 384 1039 1237 1421 Q4LDE5 3e-84 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 39863 XM_044317337.1 696 384 1039 1237 1421 Q4LDE5 1.9e-83 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 39864 XM_044317337.1 696 384 1039 1237 1421 Q4LDE5 1.63e-51 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38) Homo sapiens (Human) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0036303; GO:0048014; GO:0120193 39865 XM_044327661.1 51 8 24 31 23 NA NA NA NA NA NA 39866 XM_044308196.1 0 0 0 1 16 NA NA NA NA NA NA 39867 XM_044326250.1 90 40 58 66 36 NA NA NA NA NA NA 39868 XM_044307973.1 166 39 30 95 137 NA NA NA NA NA NA 39869 XM_044328153.1 30 12 2 13 2 NA NA NA NA NA NA 39870 XR_006392924.1 41 2 25 5 151 NA NA NA NA NA NA 39871 XM_029340361.2 44 17 0 30 0 Q9R1C8 3.55e-23 5-hydroxytryptamine receptor 6 (5-HT-6) (5-HT6) (Serotonin receptor 6) Mus musculus (Mouse) cerebral cortex cell migration [GO:0021795]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; learning [GO:0007612]; long-term synaptic potentiation [GO:0060291]; negative regulation of acetylcholine secretion, neurotransmission [GO:0014058]; negative regulation of gamma-aminobutyric acid secretion [GO:0014053]; negative regulation of glutamate secretion [GO:0014050]; positive regulation of dopamine secretion [GO:0033603]; positive regulation of gamma-aminobutyric acid secretion [GO:0014054]; positive regulation of TOR signaling [GO:0032008] GO:0004993; GO:0005886; GO:0005929; GO:0007187; GO:0007268; GO:0007612; GO:0014050; GO:0014053; GO:0014054; GO:0014058; GO:0021795; GO:0030425; GO:0030594; GO:0032008; GO:0033603; GO:0045202; GO:0060291 39872 XM_029356166.2 7 16 28 24 71 O13076 1.66e-22 Adenosine receptor A2b (Adenosine receptor 2b) Gallus gallus (Chicken) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cellular response to extracellular stimulus [GO:0031668]; cGMP-mediated signaling [GO:0019934]; G protein-coupled receptor signaling pathway [GO:0007186]; mast cell degranulation [GO:0043303]; positive regulation of cGMP-mediated signaling [GO:0010753]; positive regulation of chemokine production [GO:0032722]; positive regulation of chronic inflammatory response to non-antigenic stimulus [GO:0002882]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of vascular endothelial growth factor production [GO:0010575]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; relaxation of vascular associated smooth muscle [GO:0060087]; vasodilation [GO:0042311] GO:0001609; GO:0002882; GO:0004930; GO:0005886; GO:0007186; GO:0007189; GO:0010575; GO:0010753; GO:0019934; GO:0031284; GO:0031668; GO:0032722; GO:0032755; GO:0042311; GO:0043303; GO:0043306; GO:0060087; GO:0098685; GO:0098793; GO:0098978; GO:0099171 39873 XM_044308863.1 20 686 519 127 238 NA NA NA NA NA NA 39874 XM_044318709.1 23 0 0 0 16 NA NA NA NA NA NA 39875 XM_044307599.1 0 9 0 0 21 NA NA NA NA NA NA 39876 XM_029342071.2 5720 1300 891 4162 797 NA NA NA NA NA NA 39877 XM_029338823.2 5 0 30 447 117 Q28BP9 1.82e-104 FAS-associated factor 2 (UBX domain-containing protein 8) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005783; GO:0005811 39878 XM_029336837.2 90 45 84 39 157 O42409 2.84e-90 Zinc finger protein Gfi-1b (Growth factor-independent protein 1B) Gallus gallus (Chicken) chromatin organization [GO:0006325]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001227; GO:0005654; GO:0006325; GO:0006357; GO:0046872 39879 XM_029336837.2 90 45 84 39 157 O42409 5.57e-21 Zinc finger protein Gfi-1b (Growth factor-independent protein 1B) Gallus gallus (Chicken) chromatin organization [GO:0006325]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001227; GO:0005654; GO:0006325; GO:0006357; GO:0046872 39880 XM_029356939.2 906 914 576 708 550 Q91VJ5 3.7e-40 Polyglutamine-binding protein 1 (PQBP-1) (38 kDa nuclear protein containing a WW domain) (Npw38) (Polyglutamine tract-binding protein 1) Mus musculus (Mouse) activation of innate immune response [GO:0002218]; alternative mRNA splicing, via spliceosome [GO:0000380]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; neuron projection development [GO:0031175]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of non-motile cilium assembly [GO:1902857]; positive regulation of type I interferon production [GO:0032481]; regulation of dendrite morphogenesis [GO:0048814]; regulation of RNA splicing [GO:0043484] GO:0000380; GO:0002218; GO:0002230; GO:0003690; GO:0005634; GO:0005737; GO:0005813; GO:0005929; GO:0008022; GO:0010494; GO:0016604; GO:0016607; GO:0031175; GO:0032481; GO:0043021; GO:0043484; GO:0045087; GO:0048814; GO:0051607; GO:0071360; GO:0071598; GO:0097546; GO:1902857 39881 XM_029347374.2 0 0 0 57 41 NA NA NA NA NA NA 39882 XM_029329842.2 20 6 0 12 19 P49147 3.24e-122 Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase); Lysophospholipase (EC 3.1.1.5)] Gallus gallus (Chicken) arachidonic acid metabolic process [GO:0019369]; arachidonic acid secretion [GO:0050482]; cellular response to antibiotic [GO:0071236]; establishment of localization in cell [GO:0051649]; glycerophospholipid catabolic process [GO:0046475]; leukotriene biosynthetic process [GO:0019370]; monoacylglycerol biosynthetic process [GO:0006640]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylcholine catabolic process [GO:0034638]; phosphatidylglycerol catabolic process [GO:0034478]; platelet activating factor biosynthetic process [GO:0006663]; positive regulation of macrophage activation [GO:0043032]; positive regulation of platelet activation [GO:0010572]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of T-helper 1 type immune response [GO:0002827]; prostaglandin biosynthetic process [GO:0001516]; regulation of cell population proliferation [GO:0042127] GO:0000139; GO:0001516; GO:0002827; GO:0004622; GO:0004623; GO:0005509; GO:0005544; GO:0005634; GO:0005635; GO:0005783; GO:0005794; GO:0005829; GO:0006640; GO:0006663; GO:0008374; GO:0010314; GO:0010572; GO:0019369; GO:0019370; GO:0031410; GO:0032266; GO:0032308; GO:0034478; GO:0034638; GO:0036151; GO:0042127; GO:0043032; GO:0046475; GO:0047498; GO:0047499; GO:0050482; GO:0051649; GO:0070273; GO:0071236; GO:0102545; GO:1902387 39883 XM_029330416.2 0 89 56 113 23 Q9EQD2 1.04e-37 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 39884 XR_006398193.1 0 0 0 2 8 NA NA NA NA NA NA 39885 XM_029338797.2 0 0 3 6 1 NA NA NA NA NA NA 39886 XM_044313061.1 74 144 0 34 88 NA NA NA NA NA NA 39887 XR_006395648.1 212 104 64 209 50 NA NA NA NA NA NA 39888 XM_044311426.1 1 28 29 26 5 Q5AXT5 9.29e-33 ATP-dependent DNA helicase PIF1 (EC 3.6.4.12) (DNA repair and recombination helicase PIF1) Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; mitochondrial genome maintenance [GO:0000002]; telomere maintenance [GO:0000723] GO:0000002; GO:0000723; GO:0003677; GO:0005524; GO:0005634; GO:0005657; GO:0005739; GO:0006260; GO:0006281; GO:0006310; GO:0016887; GO:0032508; GO:0043139 39889 XM_044310238.1 0 0 0 0 7 NA NA NA NA NA NA 39890 XM_044321848.1 476 706 88 1224 421 NA NA NA NA NA NA 39891 XM_029343980.2 360 138 0 984 0 B9EJ86 0 Oxysterol-binding protein-related protein 8 (ORP-8) (OSBP-related protein 8) Mus musculus (Mouse) activation of protein kinase B activity [GO:0032148]; fat cell differentiation [GO:0045444]; negative regulation of cell migration [GO:0030336]; negative regulation of sequestering of triglyceride [GO:0010891]; phospholipid transport [GO:0015914]; positive regulation of glucose import [GO:0046326]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of protein kinase B signaling [GO:0051897]; protein localization to nuclear pore [GO:0090204] GO:0001786; GO:0005783; GO:0005789; GO:0005829; GO:0010891; GO:0015248; GO:0015485; GO:0015914; GO:0016020; GO:0030336; GO:0031965; GO:0032148; GO:0032541; GO:0032934; GO:0043231; GO:0045444; GO:0046326; GO:0046628; GO:0051897; GO:0070273; GO:0090204; GO:0140343 39892 XM_029358206.2 2569 2108 1116 1825 1704 O95563 8.24e-40 Mitochondrial pyruvate carrier 2 (Brain protein 44) Homo sapiens (Human) mitochondrial pyruvate transmembrane transport [GO:0006850]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774] GO:0005634; GO:0005739; GO:0005743; GO:0006850; GO:0035774; GO:0042802; GO:0050833; GO:0098800 39893 XM_029342910.2 61 154 49 404 457 Q16U49 0 Mediator of RNA polymerase II transcription subunit 14 (Mediator complex subunit 14) Aedes aegypti (Yellowfever mosquito) (Culex aegypti) regulation of transcription by RNA polymerase II [GO:0006357] GO:0003712; GO:0006357; GO:0016592 39894 XR_006397838.1 0 0 0 12 6 NA NA NA NA NA NA 39895 XR_006391973.1 0 0 0 19 0 NA NA NA NA NA NA 39896 XR_006393917.1 41 2 25 5 151 NA NA NA NA NA NA 39897 XR_003825544.2 8 0 0 4 0 NA NA NA NA NA NA 39898 XM_029355389.2 418 398 170 377 217 NA NA NA NA NA NA 39899 XM_029346368.2 46 23 32 0 83 NA NA NA NA NA NA 39900 XM_029346196.2 90 53 74 0 0 Q9I8C7 8.72e-90 Neuronal acetylcholine receptor subunit alpha-10 (Alpha 10 nAChR) (Nicotinic acetylcholine receptor subunit alpha-10) (NACHR alpha-10) Gallus gallus (Chicken) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; response to auditory stimulus [GO:0010996]; signal transduction [GO:0007165] GO:0004888; GO:0005231; GO:0005262; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0010996; GO:0022848; GO:0030594; GO:0034220; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051899; GO:1904315 39901 XM_029343546.2 24 35 33 0 101 NA NA NA NA NA NA 39902 XR_003824225.2 4 1 0 5 9 NA NA NA NA NA NA 39903 XM_029328640.2 0 0 61 241 59 Q00168 8.74e-67 Calcium/calmodulin-dependent protein kinase type II alpha chain (CaM-kinase II alpha chain) (EC 2.7.11.17) Drosophila melanogaster (Fruit fly) cellular response to starvation [GO:0009267]; chemical synaptic transmission [GO:0007268]; courtship behavior [GO:0007619]; learning or memory [GO:0007611]; long-term memory [GO:0007616]; male courtship behavior [GO:0008049]; negative regulation of cytokine production [GO:0001818]; negative regulation of lipid storage [GO:0010888]; neuromuscular junction development [GO:0007528]; peptidyl-threonine autophosphorylation [GO:1990443]; positive regulation of synaptic transmission, dopaminergic [GO:0032226]; protein phosphorylation [GO:0006468]; regulation of filopodium assembly [GO:0051489]; regulation of ovulation [GO:0060278]; regulation of synaptic assembly at neuromuscular junction [GO:0008582] GO:0001818; GO:0004674; GO:0004683; GO:0005516; GO:0005524; GO:0005737; GO:0006468; GO:0007268; GO:0007528; GO:0007611; GO:0007616; GO:0007619; GO:0008049; GO:0008582; GO:0009267; GO:0010888; GO:0030424; GO:0030425; GO:0032226; GO:0043005; GO:0045211; GO:0048786; GO:0051489; GO:0060278; GO:0106310; GO:1990443 39904 XM_044316904.1 2010 3171 1397 1981 1187 Q3ZBK2 2.1e-54 Peroxiredoxin-like 2A (Peroxiredoxin-like 2 activated in M-CSF stimulated monocytes) (Protein PAMM) (Redox-regulatory protein FAM213A) Bos taurus (Bovine) regulation of osteoclast differentiation [GO:0045670] GO:0005576; GO:0005737; GO:0016209; GO:0045670 39905 XR_003824977.2 66 66 79 16 94 NA NA NA NA NA NA 39906 XM_029324581.2 1366 2239 1011 1093 1146 F1Q7H8 9.79e-102 Palmitoyltransferase ZDHHC20-A (EC 2.3.1.225) (Acyltransferase ZDHHC20-A) (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 20-A) Danio rerio (Zebrafish) (Brachydanio rerio) peptidyl-L-cysteine S-palmitoylation [GO:0018230]; protein palmitoylation [GO:0018345]; protein targeting to membrane [GO:0006612] GO:0000139; GO:0005783; GO:0005789; GO:0005794; GO:0005886; GO:0006612; GO:0018230; GO:0018345; GO:0019705; GO:0019706; GO:0033116; GO:0046872; GO:0048471; GO:0140439 39907 XR_006398196.1 0 0 2 0 21 NA NA NA NA NA NA 39908 XM_044317885.1 0 0 12 0 7 Q9CWQ2 7.67e-29 Zinc finger SWIM domain-containing protein 7 (SWIM domain-containing and Srs2-interacting protein 1 homolog) Mus musculus (Mouse) double-strand break repair via homologous recombination [GO:0000724]; protein stabilization [GO:0050821] GO:0000724; GO:0005634; GO:0008270; GO:0050821; GO:0097196 39909 XM_029324004.2 6 6 41 37 77 A5PJJ7 9.52e-102 Short-chain dehydrogenase/reductase family 16C member 6 (EC 1.1.1.-) Bos taurus (Bovine) NA GO:0005811; GO:0016616 39910 XM_044311243.1 45 26 25 18 17 NA NA NA NA NA NA 39911 XR_006393260.1 8 0 4 0 1 NA NA NA NA NA NA 39912 XM_044316290.1 22 5 18 19 99 NA NA NA NA NA NA 39913 XM_044319933.1 12 34 9 0 27 Q94K49 1.75e-22 Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1 (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) epigenetic regulation of gene expression [GO:0040029] GO:0003682; GO:0004518; GO:0005634; GO:0035098; GO:0035102; GO:0040029; GO:0046872 39914 XM_044320690.1 14 6 12 90 278 NA NA NA NA NA NA 39915 XM_044327294.1 0 7 0 0 11 NA NA NA NA NA NA 39916 XM_029330587.2 33777 29628 17866 22928 9107 NA NA NA NA NA NA 39917 XM_044316076.1 0 8 0 2 0 NA NA NA NA NA NA 39918 XM_029348399.2 73 0 0 117 76 Q9JJS6 9.94e-106 Beta,beta-carotene 15,15'-dioxygenase (EC 1.13.11.63) (Beta-carotene dioxygenase 1) (Beta-carotene oxygenase 1) Mus musculus (Mouse) beta-carotene metabolic process [GO:1901810]; carotene catabolic process [GO:0016121]; retinal metabolic process [GO:0042574]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572] GO:0001523; GO:0003834; GO:0005829; GO:0010436; GO:0016121; GO:0042572; GO:0042574; GO:0046872; GO:1901810 39919 XR_003828008.2 4 0 11 9 78 NA NA NA NA NA NA 39920 XR_006395619.1 61 20 46 56 92 NA NA NA NA NA NA 39921 XM_029337589.2 396 521 357 381 235 P79691 6.55e-23 Sonic hedgehog protein (SHHA) (EC 3.1.-.-) (Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains) (ShhNC) [Cleaved into: Sonic hedgehog protein A N-product (Shh N-terminal processed signaling domains) (ShhNp) (Sonic hedgehog protein N-product) (ShhN)] Carassius auratus (Goldfish) cell-cell signaling [GO:0007267]; intein-mediated protein splicing [GO:0016539]; positive regulation of smoothened signaling pathway [GO:0045880]; protein autoprocessing [GO:0016540]; self proteolysis [GO:0097264]; system development [GO:0048731] GO:0000139; GO:0005789; GO:0005886; GO:0007267; GO:0008233; GO:0016539; GO:0016540; GO:0045880; GO:0046872; GO:0048731; GO:0097264; GO:0140853 39922 XM_044312406.1 112 48 114 86 367 NA NA NA NA NA NA 39923 XR_006392368.1 139 16 119 0 34 NA NA NA NA NA NA 39924 XM_029347215.2 52 78 32 84 212 NA NA NA NA NA NA 39925 XM_029355291.2 104 135 39 115 124 Q9JHE4 1.07e-43 Galactosylceramide sulfotransferase (GalCer sulfotransferase) (EC 2.8.2.11) (3'-phosphoadenosine-5'-phosphosulfate:GalCer sulfotransferase) (3'-phosphoadenylylsulfate:galactosylceramide 3'-sulfotransferase) (Cerebroside sulfotransferase) Mus musculus (Mouse) galactosylceramide biosynthetic process [GO:0006682]; galactosylceramide metabolic process [GO:0006681]; glycerolipid metabolic process [GO:0046486]; glycolipid biosynthetic process [GO:0009247]; myelination [GO:0042552]; spermatogenesis [GO:0007283]; sphingolipid metabolic process [GO:0006665] GO:0000139; GO:0001733; GO:0006665; GO:0006681; GO:0006682; GO:0007283; GO:0008146; GO:0009247; GO:0016020; GO:0042552; GO:0046486; GO:0050694 39926 XM_044329270.1 63 1 48 28 103 NA NA NA NA NA NA 39927 XM_044326953.1 18 0 34 7 3 NA NA NA NA NA NA 39928 XM_044317401.1 276 28 39 150 155 O62852 1.6e-39 Short transient receptor potential channel 5 (Rtrp5) (TrpC5) (Capacitative calcium entry channel 2) (CCE2) Oryctolagus cuniculus (Rabbit) neuron apoptotic process [GO:0051402]; phosphatidylserine exposure on apoptotic cell surface [GO:0070782] GO:0005262; GO:0005886; GO:0034704; GO:0051402; GO:0070679; GO:0070782 39929 XM_044322705.1 12 5 6 6 22 Q96AY4 8.91e-154 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 39930 XM_044322705.1 12 5 6 6 22 Q96AY4 1.01e-140 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 39931 XM_044322705.1 12 5 6 6 22 Q96AY4 1.81e-127 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 39932 XM_044322705.1 12 5 6 6 22 Q96AY4 3.46e-95 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 39933 XM_044322705.1 12 5 6 6 22 Q96AY4 3.23e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 39934 XM_029358342.2 66 65 20 95 44 NA NA NA NA NA NA 39935 XR_006392340.1 47 13 13 43 197 NA NA NA NA NA NA 39936 XM_044323251.1 6 0 12 31 0 NA NA NA NA NA NA 39937 XM_044328508.1 69 0 9 0 41 NA NA NA NA NA NA 39938 XM_044306873.1 22 0 0 0 11 Q15858 0 Sodium channel protein type 9 subunit alpha (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1) (PN1) (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) Homo sapiens (Human) behavioral response to formalin induced pain [GO:0061368]; circadian rhythm [GO:0007623]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; inflammatory response [GO:0006954]; membrane depolarization during action potential [GO:0086010]; negative regulation of action potential [GO:0045759]; neuronal action potential [GO:0019228]; post-embryonic development [GO:0009791]; regulation of ion transmembrane transport [GO:0034765]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to toxic substance [GO:0009636]; sensory perception of pain [GO:0019233]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814] GO:0001518; GO:0005244; GO:0005248; GO:0005886; GO:0006814; GO:0006954; GO:0007623; GO:0009408; GO:0009409; GO:0009636; GO:0009791; GO:0019228; GO:0019233; GO:0030424; GO:0031402; GO:0034765; GO:0035725; GO:0045759; GO:0050965; GO:0050974; GO:0061368; GO:0086010 39939 XM_044306873.1 22 0 0 0 11 Q15858 1.83e-67 Sodium channel protein type 9 subunit alpha (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1) (PN1) (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) Homo sapiens (Human) behavioral response to formalin induced pain [GO:0061368]; circadian rhythm [GO:0007623]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; inflammatory response [GO:0006954]; membrane depolarization during action potential [GO:0086010]; negative regulation of action potential [GO:0045759]; neuronal action potential [GO:0019228]; post-embryonic development [GO:0009791]; regulation of ion transmembrane transport [GO:0034765]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to toxic substance [GO:0009636]; sensory perception of pain [GO:0019233]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814] GO:0001518; GO:0005244; GO:0005248; GO:0005886; GO:0006814; GO:0006954; GO:0007623; GO:0009408; GO:0009409; GO:0009636; GO:0009791; GO:0019228; GO:0019233; GO:0030424; GO:0031402; GO:0034765; GO:0035725; GO:0045759; GO:0050965; GO:0050974; GO:0061368; GO:0086010 39940 XM_044327836.1 6 0 0 0 0 NA NA NA NA NA NA 39941 XM_029336547.2 0 1 5 2 19 Q6GNV7 9.26e-64 Solute carrier family 49 member 4 homolog (Disrupted in renal carcinoma protein 2 homolog) Xenopus laevis (African clawed frog) NA GO:0005765; GO:0022857 39942 XM_029336547.2 0 1 5 2 19 Q6GNV7 9.26e-64 Solute carrier family 49 member 4 homolog (Disrupted in renal carcinoma protein 2 homolog) Xenopus laevis (African clawed frog) NA GO:0005765; GO:0022857 39943 XM_044320510.1 81 0 0 11 0 NA NA NA NA NA NA 39944 XM_044322418.1 27 0 9 77 44 NA NA NA NA NA NA 39945 XR_006392890.1 41 2 25 5 151 NA NA NA NA NA NA 39946 XM_044318930.1 4 2 0 2 58 Q61382 2.01e-49 TNF receptor-associated factor 4 (EC 2.3.2.27) (Cysteine-rich motif associated to RING and Traf domains protein 1) Mus musculus (Mouse) activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; innate immune response [GO:0045087]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein kinase activity [GO:0045860]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; respiratory gaseous exchange by respiratory system [GO:0007585]; respiratory tube development [GO:0030323] GO:0001650; GO:0005164; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0005923; GO:0006915; GO:0007250; GO:0007585; GO:0008270; GO:0016740; GO:0019901; GO:0030323; GO:0031625; GO:0031996; GO:0042802; GO:0042981; GO:0043122; GO:0043161; GO:0045087; GO:0045860; GO:0046330; GO:0048471; GO:0050699 39947 XR_003826039.2 2 2 0 10 14 NA NA NA NA NA NA 39948 XM_044326267.1 13 6 18 30 6 NA NA NA NA NA NA 39949 XM_029350637.2 608 491 132 459 569 NA NA NA NA NA NA 39950 XM_029342110.2 1108 1048 772 2486 2636 Q6GLC9 1.26e-116 Fragile X messenger ribonucleoprotein 1 homolog (XtFmrp) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) brain development [GO:0007420]; branching morphogenesis of a nerve [GO:0048755]; cartilage development [GO:0051216]; cognition [GO:0050890]; DNA repair [GO:0006281]; forebrain-midbrain boundary formation [GO:0021905]; glutamate receptor signaling pathway [GO:0007215]; mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; negative regulation of cytoplasmic translation [GO:2000766]; negative regulation of gene expression [GO:0010629]; negative regulation of long-term synaptic depression [GO:1900453]; negative regulation of synaptic vesicle exocytosis [GO:2000301]; negative regulation of translation [GO:0017148]; negative regulation of translational initiation [GO:0045947]; negative regulation of voltage-gated calcium channel activity [GO:1901386]; neural crest cell fate specification [GO:0014036]; neuron projection morphogenesis [GO:0048812]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; positive regulation of mRNA binding [GO:1902416]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of receptor internalization [GO:0002092]; positive regulation of translation [GO:0045727]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of dendritic spine development [GO:0060998]; regulation of filopodium assembly [GO:0051489]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of mRNA modification [GO:0090365]; regulation of mRNA stability [GO:0043488]; regulation of neuronal action potential [GO:0098908]; regulation of neurotransmitter secretion [GO:0046928]; RNA splicing [GO:0008380]; skeletal muscle organ development [GO:0060538] GO:0000381; GO:0000775; GO:0002092; GO:0002151; GO:0003682; GO:0003723; GO:0003729; GO:0003730; GO:0005634; GO:0005654; GO:0005694; GO:0005730; GO:0005737; GO:0005844; GO:0006281; GO:0006397; GO:0007215; GO:0007420; GO:0008017; GO:0008266; GO:0008380; GO:0010369; GO:0010494; GO:0010629; GO:0014036; GO:0014069; GO:0017148; GO:0019897; GO:0021905; GO:0030371; GO:0030424; GO:0030425; GO:0030426; GO:0032433; GO:0033592; GO:0034046; GO:0035064; GO:0035197; GO:0035198; GO:0035613; GO:0036464; GO:0042734; GO:0042803; GO:0042995; GO:0043005; GO:0043197; GO:0043204; GO:0043488; GO:0043679; GO:0045202; GO:0045211; GO:0045727; GO:0045947; GO:0046928; GO:0046982; GO:0048027; GO:0048471; GO:0048755; GO:0048812; GO:0050890; GO:0051028; GO:0051216; GO:0051489; GO:0051491; GO:0060538; GO:0060964; GO:0060998; GO:0060999; GO:0070840; GO:0071598; GO:0090365; GO:0097386; GO:0098793; GO:0098794; GO:0098908; GO:1900453; GO:1901386; GO:1901800; GO:1902416; GO:1902737; GO:1990812; GO:1990825; GO:1990904; GO:2000301; GO:2000637; GO:2000766 39951 XM_029337817.2 530 263 142 361 502 NA NA NA NA NA NA 39952 XM_044328591.1 5 15 0 0 27 NA NA NA NA NA NA 39953 XM_029325616.2 682 1023 769 612 552 NA NA NA NA NA NA 39954 XR_006394188.1 41 3 31 2 21 NA NA NA NA NA NA 39955 XM_044320465.1 4819 9260 4650 10645 6243 Q5R606 0 Heat shock protein 105 kDa (Heat shock 110 kDa protein) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0000774; GO:0005524; GO:0005737; GO:0140662 39956 XM_044318872.1 862 703 225 760 812 Q9BSW2 4.16e-55 EF-hand calcium-binding domain-containing protein 4B (Calcium release-activated calcium channel regulator 2A) (CRAC channel regulator 2A) (Calcium release-activated channel regulator 2A) (Ras-related protein Rab-46) Homo sapiens (Human) activation of store-operated calcium channel activity [GO:0032237]; endosomal transport [GO:0016197]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of JNK cascade [GO:0046330]; response to histamine [GO:0034776]; store-operated calcium entry [GO:0002115]; T-helper 1 cell differentiation [GO:0045063] GO:0000139; GO:0001772; GO:0002115; GO:0003924; GO:0005509; GO:0005525; GO:0005576; GO:0005737; GO:0005815; GO:0005886; GO:0016020; GO:0016197; GO:0031982; GO:0032237; GO:0032588; GO:0033093; GO:0034776; GO:0035580; GO:0045063; GO:0046330; GO:0051928 39957 XM_044318872.1 862 703 225 760 812 Q9BSW2 3.95e-35 EF-hand calcium-binding domain-containing protein 4B (Calcium release-activated calcium channel regulator 2A) (CRAC channel regulator 2A) (Calcium release-activated channel regulator 2A) (Ras-related protein Rab-46) Homo sapiens (Human) activation of store-operated calcium channel activity [GO:0032237]; endosomal transport [GO:0016197]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of JNK cascade [GO:0046330]; response to histamine [GO:0034776]; store-operated calcium entry [GO:0002115]; T-helper 1 cell differentiation [GO:0045063] GO:0000139; GO:0001772; GO:0002115; GO:0003924; GO:0005509; GO:0005525; GO:0005576; GO:0005737; GO:0005815; GO:0005886; GO:0016020; GO:0016197; GO:0031982; GO:0032237; GO:0032588; GO:0033093; GO:0034776; GO:0035580; GO:0045063; GO:0046330; GO:0051928 39958 XM_044321670.1 1 1 2 0 16 NA NA NA NA NA NA 39959 XM_044308798.1 109 16 43 14 69 NA NA NA NA NA NA 39960 XM_029340174.2 3816 2839 1675 3848 3741 Q5ZLR5 6.2e-87 Cytochrome b-c1 complex subunit Rieske, mitochondrial (EC 7.1.1.8) (Complex III subunit 5) (Cytochrome b-c1 complex subunit 5) (Rieske iron-sulfur protein) (RISP) (Rieske protein UQCRFS1) (Ubiquinol-cytochrome c reductase iron-sulfur subunit) [Cleaved into: Cytochrome b-c1 complex subunit 9 (Su9) (Subunit 9) (Complex III subunit IX) (UQCRFS1 mitochondrial targeting sequence) (UQCRFS1 MTS)] Gallus gallus (Chicken) mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122] GO:0005750; GO:0006122; GO:0008121; GO:0016491; GO:0046872; GO:0051537 39961 XM_044319235.1 0 0 0 65 53 NA NA NA NA NA NA 39962 XM_029354477.2 71 15 35 42 5 Q09325 3.42e-147 Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (EC 2.4.1.101) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I) (GNT-I) (GlcNAc-T I) Rattus norvegicus (Rat) in utero embryonic development [GO:0001701]; protein glycosylation [GO:0006486]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279]; UDP-N-acetylglucosamine catabolic process [GO:0006049] GO:0000139; GO:0001701; GO:0003827; GO:0005794; GO:0006049; GO:0006486; GO:0006487; GO:0008375; GO:0018279; GO:0030145; GO:0048471 39963 XM_044318391.1 30 2 79 45 76 NA NA NA NA NA NA 39964 XM_029336566.2 763 801 534 842 1156 Q4R6V2 0 T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) binding of sperm to zona pellucida [GO:0007339]; chaperone-mediated protein folding [GO:0061077]; positive regulation of establishment of protein localization to telomere [GO:1904851]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein stabilization [GO:0050821]; response to virus [GO:0009615]; toxin transport [GO:1901998] GO:0003730; GO:0005524; GO:0005813; GO:0005832; GO:0005874; GO:0007339; GO:0009615; GO:0016887; GO:0031681; GO:0032212; GO:0044297; GO:0048027; GO:0048487; GO:0050821; GO:0051082; GO:0061077; GO:0140662; GO:1901998; GO:1904851 39965 XM_029331556.2 191 192 23 115 70 NA NA NA NA NA NA 39966 XM_029324401.2 0 0 2 6 14 NA NA NA NA NA NA 39967 XM_044325134.1 1631 298 398 57 495 NA NA NA NA NA NA 39968 XM_044327626.1 112 113 55 91 39 Q8WV83 4.28e-109 Solute carrier family 35 member F5 (Hepatitis C virus NS5A-transactivated protein 3) (HCV NS5A-transactivated protein 3) Homo sapiens (Human) NA GO:0016020 39969 XM_029340541.2 647 471 436 692 649 Q9BZJ0 0 Crooked neck-like protein 1 (Crooked neck homolog) (hCrn) Homo sapiens (Human) mRNA splicing, via spliceosome [GO:0000398]; spliceosomal complex assembly [GO:0000245] GO:0000245; GO:0000398; GO:0000974; GO:0003723; GO:0005634; GO:0005654; GO:0005681; GO:0016607; GO:0071007; GO:0071013; GO:0071014 39970 XM_044311603.1 7 5 8 2 16 NA NA NA NA NA NA 39971 XM_044317945.1 127 99 111 163 203 Q6TDP4 8.82e-35 Kelch-like protein 17 (Actinfilin) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; protein ubiquitination [GO:0016567]; regulation protein catabolic process at postsynapse [GO:0140252] GO:0005615; GO:0007420; GO:0014069; GO:0015629; GO:0016567; GO:0030036; GO:0031208; GO:0032839; GO:0043025; GO:0051015; GO:0060090; GO:0098978; GO:0140252 39972 XM_029328531.2 8152 7502 4361 8296 8243 P11833 0 Tubulin beta chain (Beta-tubulin) Paracentrotus lividus (Common sea urchin) microtubule-based process [GO:0007017] GO:0003924; GO:0005200; GO:0005525; GO:0005737; GO:0005874; GO:0007017; GO:0046872 39973 XM_029352933.2 6 10 0 0 6 NA NA NA NA NA NA 39974 XR_006397064.1 10 4 0 0 11 NA NA NA NA NA NA 39975 XM_029336574.2 3524 2956 2520 2045 1578 Q66I67 5.3e-47 Intraflagellar transport protein 20 homolog Danio rerio (Zebrafish) (Brachydanio rerio) cell differentiation [GO:0030154]; centrosome localization [GO:0051642]; intraciliary transport [GO:0042073]; protein localization to cilium [GO:0061512]; regulation of platelet-derived growth factor receptor-alpha signaling pathway [GO:2000583]; spermatogenesis [GO:0007283] GO:0001669; GO:0005794; GO:0005813; GO:0005814; GO:0005929; GO:0005930; GO:0007283; GO:0030154; GO:0030992; GO:0036064; GO:0042073; GO:0051642; GO:0061512; GO:2000583 39976 XM_029334119.2 62 0 22 51 199 NA NA NA NA NA NA 39977 XR_006394019.1 217 167 82 216 86 NA NA NA NA NA NA 39978 XM_044323521.1 0 0 1 10 0 NA NA NA NA NA NA 39979 XR_003827258.2 2174 1970 1308 1741 1253 NA NA NA NA NA NA 39980 XM_029334612.2 23676 17190 8662 12975 10399 Q5ZLC5 0 ATP synthase subunit beta, mitochondrial (EC 7.1.2.2) (ATP synthase F1 subunit beta) Gallus gallus (Chicken) angiogenesis [GO:0001525]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776] GO:0001525; GO:0005524; GO:0005739; GO:0005753; GO:0042776; GO:0045261; GO:0046933; GO:0046961 39981 XM_044307474.1 0 9 4 3 1 NA NA NA NA NA NA 39982 XM_029340226.2 3683 3680 1695 2894 2525 Q5RCS0 0 Autophagy-related protein 9A (APG9-like 1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) autophagosome assembly [GO:0000045]; bone morphogenesis [GO:0060349]; positive regulation of necrotic cell death [GO:0010940] GO:0000045; GO:0000139; GO:0000421; GO:0005739; GO:0005789; GO:0005794; GO:0005802; GO:0010940; GO:0017128; GO:0031902; GO:0031966; GO:0034045; GO:0055038; GO:0060349 39983 XM_029337925.2 20 6 36 40 43 NA NA NA NA NA NA 39984 XM_044326512.1 0 67 34 79 49 F1QZ15 1.06e-39 EKC/KEOPS complex subunit TPRKB (PRPK-binding protein) (TP53RK-binding protein) Danio rerio (Zebrafish) (Brachydanio rerio) tRNA threonylcarbamoyladenosine modification [GO:0002949] GO:0000408; GO:0002949; GO:0005634; GO:0005737; GO:0005829 39985 XM_044309053.1 4 12 20 20 1 P86982 5.04e-22 Insoluble matrix shell protein 1 (IMSP1) Ruditapes philippinarum (Japanese littleneck clam) (Venerupis philippinarum) NA GO:0005576 39986 XM_044320708.1 0 0 0 0 9 NA NA NA NA NA NA 39987 XM_029355695.2 656 516 502 809 675 Q24322 2.86e-53 Semaphorin-1A (Semaphorin-I) (Sema I) Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; dendrite morphogenesis [GO:0048813]; motor neuron axon guidance [GO:0008045]; negative chemotaxis [GO:0050919]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of cell size [GO:0045792]; positive regulation of cell migration [GO:0030335]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in regulation of photoreceptor cell axon guidance [GO:2000305]; synapse assembly [GO:0007416]; synaptic target recognition [GO:0008039] GO:0005615; GO:0005886; GO:0007411; GO:0007416; GO:0008039; GO:0008045; GO:0008201; GO:0016020; GO:0016199; GO:0030215; GO:0030335; GO:0045499; GO:0045792; GO:0048813; GO:0048843; GO:0050919; GO:0071526; GO:2000305 39988 XM_029346831.2 129 224 135 113 49 NA NA NA NA NA NA 39989 XM_029341388.2 1189 707 541 1232 984 Q13009 2.27e-145 Rho guanine nucleotide exchange factor TIAM1 (T-lymphoma invasion and metastasis-inducing protein 1) (TIAM-1) Homo sapiens (Human) activation of GTPase activity [GO:0090630]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; ephrin receptor signaling pathway [GO:0048013]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of protein binding [GO:0032092]; protein-containing complex assembly [GO:0065003]; Rac protein signal transduction [GO:0016601]; regulation of dopaminergic neuron differentiation [GO:1904338]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of non-canonical Wnt signaling pathway [GO:2000050]; regulation of small GTPase mediated signal transduction [GO:0051056]; small GTPase mediated signal transduction [GO:0007264]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0005085; GO:0005829; GO:0005886; GO:0005911; GO:0007160; GO:0007264; GO:0008284; GO:0008289; GO:0010717; GO:0010718; GO:0016020; GO:0016477; GO:0016601; GO:0019900; GO:0030335; GO:0031234; GO:0032092; GO:0044291; GO:0045202; GO:0048013; GO:0050772; GO:0051056; GO:0060071; GO:0065003; GO:0090630; GO:1904338; GO:2000050 39990 XM_044315957.1 0 13 2 2 7 NA NA NA NA NA NA 39991 XM_044314421.1 0 6 1 0 3 NA NA NA NA NA NA 39992 XM_044310164.1 22 49 41 52 32 NA NA NA NA NA NA 39993 XM_029332164.2 9917 5649 3545 9227 6910 B8UU51 0 Galaxin-2 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 39994 XM_044323031.1 58 23 34 154 51 NA NA NA NA NA NA 39995 XM_044306832.1 10 37 27 14 38 NA NA NA NA NA NA 39996 XR_006393856.1 172 47 181 27 849 NA NA NA NA NA NA 39997 XR_006392624.1 264 216 250 398 313 NA NA NA NA NA NA 39998 XM_044311309.1 34 10 21 41 11 Q96AY4 7.56e-76 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 39999 XM_044311309.1 34 10 21 41 11 Q96AY4 3.26e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 40000 XM_044311309.1 34 10 21 41 11 Q96AY4 3.08e-72 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 40001 XM_044311309.1 34 10 21 41 11 Q96AY4 1.09e-65 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 40002 XM_044311309.1 34 10 21 41 11 Q96AY4 8.64e-64 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 40003 XM_044311309.1 34 10 21 41 11 Q96AY4 8.97e-64 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 40004 XM_044311309.1 34 10 21 41 11 Q96AY4 3.16e-57 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 40005 XM_044311309.1 34 10 21 41 11 Q96AY4 4.41e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 40006 XM_029334610.2 204 281 361 514 96 Q921L8 0 Polypeptide N-acetylgalactosaminyltransferase 11 (EC 2.4.1.41) (Polypeptide GalNAc transferase 11) (GalNAc-T11) (pp-GaNTase 11) (Protein-UDP acetylgalactosaminyltransferase 11) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 11) Mus musculus (Mouse) cilium assembly [GO:0060271]; determination of left/right symmetry [GO:0007368]; Notch receptor processing [GO:0007220]; Notch signaling involved in heart development [GO:0061314]; protein O-linked glycosylation [GO:0006493]; protein O-linked glycosylation via threonine [GO:0018243]; regulation of Notch signaling pathway [GO:0008593] GO:0000139; GO:0004653; GO:0005112; GO:0005794; GO:0006493; GO:0007220; GO:0007368; GO:0008593; GO:0018243; GO:0030246; GO:0046872; GO:0060271; GO:0061314 40007 XR_006391752.1 33 23 17 37 28 NA NA NA NA NA NA 40008 XM_044329132.1 37 43 9 9 37 NA NA NA NA NA NA 40009 XM_029356469.2 6193 4464 5908 13565 8969 NA NA NA NA NA NA 40010 XM_044328227.1 273 854 61 43 238 Q8K2J9 1.1e-68 BTB/POZ domain-containing protein 6 Mus musculus (Mouse) neurogenesis [GO:0022008] GO:0005829; GO:0022008 40011 XM_044313737.1 0 0 7 5 0 NA NA NA NA NA NA 40012 XM_044307817.1 33 15 0 7 13 NA NA NA NA NA NA 40013 XM_029335649.2 0 41 0 0 0 Q5F478 4.69e-77 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (PP6-ARS-B) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-B) (Ankyrin repeat domain-containing protein 44) Gallus gallus (Chicken) NA NA 40014 XM_029335649.2 0 41 0 0 0 Q5F478 1.24e-73 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (PP6-ARS-B) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-B) (Ankyrin repeat domain-containing protein 44) Gallus gallus (Chicken) NA NA 40015 XM_029335649.2 0 41 0 0 0 Q5F478 1.68e-72 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (PP6-ARS-B) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-B) (Ankyrin repeat domain-containing protein 44) Gallus gallus (Chicken) NA NA 40016 XM_029335649.2 0 41 0 0 0 Q5F478 9.96e-46 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (PP6-ARS-B) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-B) (Ankyrin repeat domain-containing protein 44) Gallus gallus (Chicken) NA NA 40017 XM_044309973.1 8 0 4 3 8 NA NA NA NA NA NA 40018 XM_029356357.2 0 62 0 0 0 NA NA NA NA NA NA 40019 XM_044315017.1 26 11 0 8 0 NA NA NA NA NA NA 40020 XM_029332976.2 0 92 2 35 0 Q9H0B8 6.47e-31 Cysteine-rich secretory protein LCCL domain-containing 2 (Cysteine-rich secretory protein 11) (CRISP-11) (LCCL domain-containing cysteine-rich secretory protein 2) Homo sapiens (Human) extracellular matrix organization [GO:0030198]; face morphogenesis [GO:0060325]; lung development [GO:0030324] GO:0005539; GO:0005576; GO:0005615; GO:0008201; GO:0030133; GO:0030198; GO:0030324; GO:0031012; GO:0034774; GO:0060325; GO:0070062; GO:1904813 40021 XM_029353711.2 0 4 0 3 7 NA NA NA NA NA NA 40022 XR_006397782.1 0 0 1 0 15 NA NA NA NA NA NA 40023 XM_044307677.1 17 0 0 272 54 Q8IVE3 0 Pleckstrin homology domain-containing family H member 2 Homo sapiens (Human) negative regulation of actin filament depolymerization [GO:0030835] GO:0003779; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0016604; GO:0030027; GO:0030835; GO:0030864 40024 XM_029346985.2 601 335 239 345 429 NA NA NA NA NA NA 40025 XM_029330412.2 6 0 10 5 53 P58308 2.19e-38 Orexin receptor type 2 (Ox-2-R) (Ox2-R) (Ox2R) (Hypocretin receptor type 2) Mus musculus (Mouse) circadian sleep/wake cycle process [GO:0022410]; feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; locomotion [GO:0040011]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; regulation of circadian sleep/wake cycle, wakefulness [GO:0010840]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0004930; GO:0005886; GO:0007186; GO:0007200; GO:0007218; GO:0007631; GO:0010840; GO:0016499; GO:0017046; GO:0022410; GO:0040011; GO:0051480 40026 XM_044327527.1 90 0 57 121 76 A2RUC4 6.52e-145 tRNA wybutosine-synthesizing protein 5 (hTYW5) (tRNA yW-synthesizing protein 5) (EC 1.14.11.42) (tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-C(2))-hydroxylase) Homo sapiens (Human) wybutosine biosynthetic process [GO:0031591] GO:0000049; GO:0005506; GO:0005737; GO:0016706; GO:0031591; GO:0042803; GO:0102524 40027 XM_029339321.2 11131 10780 12363 18743 12148 Q8WPW2 5.14e-148 Pyridoxal 5'-phosphate synthase subunit SNZERR (PLP synthase subunit SNZERR) (EC 4.3.3.6) (Ethylene response protein) (PDX1) Suberites domuncula (Sponge) pyridoxal phosphate biosynthetic process [GO:0042823] GO:0036381; GO:0042823 40028 XM_044311521.1 420 272 145 662 289 Q8WVM7 1.24e-164 Cohesin subunit SA-1 (SCC3 homolog 1) (Stromal antigen 1) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic sister chromatid cohesion [GO:0034087]; localization [GO:0051179]; mitotic spindle assembly [GO:0090307]; sister chromatid cohesion [GO:0007062] GO:0000775; GO:0000785; GO:0003682; GO:0005634; GO:0005654; GO:0005694; GO:0005829; GO:0007062; GO:0008278; GO:0016363; GO:0016604; GO:0034087; GO:0051179; GO:0051301; GO:0090307; GO:0097431 40029 XM_044325070.1 36 17 9 47 37 NA NA NA NA NA NA 40030 XR_006396702.1 20 16 63 0 88 NA NA NA NA NA NA 40031 XM_029334336.2 36054 33753 22239 52157 27438 P62976 0 Polyubiquitin [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2] Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) NA GO:0005634; GO:0005737 40032 XM_029334336.2 36054 33753 22239 52157 27438 P62976 0 Polyubiquitin [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2] Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) NA GO:0005634; GO:0005737 40033 XM_029334336.2 36054 33753 22239 52157 27438 P62976 0 Polyubiquitin [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2] Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) NA GO:0005634; GO:0005737 40034 XM_029334336.2 36054 33753 22239 52157 27438 P62976 0 Polyubiquitin [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2] Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) NA GO:0005634; GO:0005737 40035 XM_029338902.2 35 13 15 55 6 NA NA NA NA NA NA 40036 XR_006393145.1 90 938 90 862 57 NA NA NA NA NA NA 40037 XR_006397813.1 317 247 146 147 228 NA NA NA NA NA NA 40038 XR_006394833.1 1 11 13 17 12 Q96CG8 2.52e-45 Collagen triple helix repeat-containing protein 1 Homo sapiens (Human) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005576; GO:0005581; GO:0005615; GO:0016477; GO:0016528; GO:0017147; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0062023; GO:0090090; GO:0090103; GO:0090177 40039 XR_006397526.1 82 32 69 117 139 Q6PDC8 1.64e-40 Major facilitator superfamily domain-containing protein 4A (Major facilitator superfamily domain-containing protein 4) Mus musculus (Mouse) NA GO:0005355; GO:0016020 40040 XM_029327076.2 2793 1564 1316 1806 1300 Q29RM3 3.16e-48 Receptor expression-enhancing protein 5 Bos taurus (Bovine) endoplasmic reticulum membrane organization [GO:0090158] GO:0033017; GO:0071782; GO:0090158 40041 XR_006391701.1 184 163 123 145 283 NA NA NA NA NA NA 40042 XR_006392932.1 41 2 25 5 151 NA NA NA NA NA NA 40043 XM_044327450.1 0 9 6 4 84 Q91ZV3 2.08e-26 Discoidin, CUB and LCCL domain-containing protein 2 (Endothelial and smooth muscle cell-derived neuropilin-like protein) Mus musculus (Mouse) negative regulation of cell growth [GO:0030308]; wound healing [GO:0042060] GO:0005886; GO:0009986; GO:0030308; GO:0038023; GO:0042060 40044 XR_006393358.1 58 14 48 70 89 NA NA NA NA NA NA 40045 XM_044313919.1 7 0 5 0 12 NA NA NA NA NA NA 40046 XM_029329415.2 792 317 393 604 1028 P47800 1.04e-23 D(1)-like dopamine receptor Oreochromis mossambicus (Mozambique tilapia) (Tilapia mossambica) regulation of biological quality [GO:0065008] GO:0004930; GO:0005886; GO:0065008 40047 XM_029356263.2 1611 1833 1175 1435 1503 Q95108 2.19e-38 Thioredoxin, mitochondrial (MTRX) (Mt-Trx) (Thioredoxin-2) Bos taurus (Bovine) cell redox homeostasis [GO:0045454] GO:0005730; GO:0005739; GO:0015035; GO:0045454 40048 XM_029349798.2 1329 189 622 1601 1723 NA NA NA NA NA NA 40049 XM_044326791.1 0 6 10 0 21 NA NA NA NA NA NA 40050 XR_003824049.2 27 17 29 12 86 NA NA NA NA NA NA 40051 XM_029331081.2 85 7 136 95 261 D3YXG0 1.97e-41 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 40052 XM_029331081.2 85 7 136 95 261 D3YXG0 3.23e-41 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 40053 XM_029331081.2 85 7 136 95 261 D3YXG0 2.12e-38 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 40054 XM_029331081.2 85 7 136 95 261 D3YXG0 7.02e-34 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 40055 XM_029331081.2 85 7 136 95 261 D3YXG0 3.03e-25 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 40056 XM_044312498.1 361 422 501 595 763 Q92997 3.3e-147 Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; intracellular signal transduction [GO:0035556]; non-canonical Wnt signaling pathway [GO:0035567]; non-canonical Wnt signaling pathway via JNK cascade [GO:0038031]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of GTPase activity [GO:0043547]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein stabilization [GO:0050821]; regulation of protein localization [GO:0032880]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0000785; GO:0001934; GO:0002020; GO:0005102; GO:0005109; GO:0005829; GO:0008013; GO:0031267; GO:0032880; GO:0035556; GO:0035567; GO:0038031; GO:0043507; GO:0043547; GO:0045893; GO:0045944; GO:0050821; GO:0060070; GO:0060071; GO:0090179; GO:0150012 40057 XM_029348620.2 55 96 254 42 78 NA NA NA NA NA NA 40058 XM_029323551.2 65 0 52 41 0 Q80TT2 1.34e-147 BAI1-associated protein 3 (BAP3) (Brain-specific angiogenesis inhibitor I-associated protein 3) (Baiap3) Mus musculus (Mouse) dense core granule maturation [GO:1990502]; exocytosis [GO:0006887]; G protein-coupled receptor signaling pathway [GO:0007186]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of neurotransmitter secretion [GO:0001956]; regulation of behavior [GO:0050795]; regulation of dense core granule exocytosis [GO:1905413]; regulation of synaptic transmission, GABAergic [GO:0032228]; retrograde transport, endosome to Golgi [GO:0042147] GO:0000149; GO:0001956; GO:0005509; GO:0005543; GO:0005829; GO:0005886; GO:0006887; GO:0007186; GO:0019905; GO:0031902; GO:0032228; GO:0032588; GO:0035774; GO:0042147; GO:0050795; GO:0050804; GO:0055038; GO:0098793; GO:0098982; GO:0099503; GO:1905413; GO:1990502 40059 XR_003825199.2 0 28 2 2 32 NA NA NA NA NA NA 40060 XM_044326927.1 62 14 92 0 24 Q8IYQ7 1.17e-163 Threonine synthase-like 1 (TSH1) Homo sapiens (Human) NA GO:0005737 40061 XM_029329403.2 1345 1349 710 934 709 NA NA NA NA NA NA 40062 XM_029333584.2 5 15 48 43 7 NA NA NA NA NA NA 40063 XM_044315818.1 5 1 22 17 10 NA NA NA NA NA NA 40064 XM_044317392.1 428 484 259 283 293 NA NA NA NA NA NA 40065 XM_029333634.2 231 101 146 173 151 NA NA NA NA NA NA 40066 XM_044308998.1 165 138 121 237 168 O43301 4.59e-122 Heat shock 70 kDa protein 12A Homo sapiens (Human) NA GO:0005524; GO:0005634; GO:0005737; GO:0070062 40067 XM_029332073.2 313 90 184 111 325 Q7T3E6 2.55e-52 Polycomb complex protein BMI-1-B (Polycomb group RING finger protein 4-B) Danio rerio (Zebrafish) (Brachydanio rerio) cerebellum development [GO:0021549]; histone H2A-K119 monoubiquitination [GO:0036353]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of transcription by RNA polymerase II [GO:0000122] GO:0000122; GO:0021549; GO:0031519; GO:0035102; GO:0036353; GO:0045814; GO:0046872; GO:1990841 40068 XM_044323197.1 99 13 10 69 0 NA NA NA NA NA NA 40069 XM_029329742.2 531 267 206 520 193 Q400C8 8.01e-52 Archaemetzincin-2 (EC 3.4.-.-) (Archeobacterial metalloproteinase-like protein 2) Mus musculus (Mouse) proteolysis [GO:0006508] GO:0006508; GO:0008237; GO:0046872 40070 XM_029357765.2 38 17 0 0 0 P21728 7.1e-31 D(1A) dopamine receptor (Dopamine D1 receptor) Homo sapiens (Human) activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adult walking behavior [GO:0007628]; astrocyte development [GO:0014002]; behavioral fear response [GO:0001662]; behavioral response to cocaine [GO:0048148]; cellular response to catecholamine stimulus [GO:0071870]; cellular response to dopamine [GO:1903351]; cerebral cortex GABAergic interneuron migration [GO:0021853]; conditioned taste aversion [GO:0001661]; dentate gyrus development [GO:0021542]; dopamine metabolic process [GO:0042417]; dopamine receptor signaling pathway [GO:0007212]; dopamine transport [GO:0015872]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; glucose import [GO:0046323]; grooming behavior [GO:0007625]; habituation [GO:0046959]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; maternal behavior [GO:0042711]; mating behavior [GO:0007617]; memory [GO:0007613]; modification of postsynaptic structure [GO:0099010]; neuronal action potential [GO:0019228]; operant conditioning [GO:0035106]; peristalsis [GO:0030432]; phospholipase C-activating dopamine receptor signaling pathway [GO:0060158]; positive regulation of cell migration [GO:0030335]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transport [GO:0043268]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; prepulse inhibition [GO:0060134]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; protein import into nucleus [GO:0006606]; protein phosphorylation [GO:0006468]; regulation of dopamine metabolic process [GO:0042053]; regulation of dopamine uptake involved in synaptic transmission [GO:0051584]; regulation of protein phosphorylation [GO:0001932]; response to amphetamine [GO:0001975]; response to xenobiotic stimulus [GO:0009410]; sensitization [GO:0046960]; striatum development [GO:0021756]; synapse assembly [GO:0007416]; synaptic transmission, glutamatergic [GO:0035249]; temperature homeostasis [GO:0001659]; transmission of nerve impulse [GO:0019226]; vasodilation [GO:0042311]; visual learning [GO:0008542] GO:0001588; GO:0001659; GO:0001661; GO:0001662; GO:0001932; GO:0001975; GO:0004930; GO:0004952; GO:0005634; GO:0005789; GO:0005886; GO:0005929; GO:0006468; GO:0006606; GO:0007187; GO:0007189; GO:0007190; GO:0007191; GO:0007212; GO:0007416; GO:0007613; GO:0007617; GO:0007625; GO:0007628; GO:0008542; GO:0009410; GO:0010628; GO:0014002; GO:0015872; GO:0019226; GO:0019228; GO:0021542; GO:0021756; GO:0021853; GO:0030335; GO:0030432; GO:0035106; GO:0035240; GO:0035249; GO:0042053; GO:0042311; GO:0042417; GO:0042711; GO:0042734; GO:0043197; GO:0043268; GO:0045211; GO:0046323; GO:0046959; GO:0046960; GO:0048148; GO:0051281; GO:0051482; GO:0051584; GO:0051968; GO:0060134; GO:0060158; GO:0060170; GO:0060291; GO:0060292; GO:0071870; GO:0071880; GO:0097730; GO:0098978; GO:0098982; GO:0099010; GO:0099171; GO:1903351; GO:2001224 40071 XM_044306764.1 15 32 10 39 54 H1AFJ5 6.16e-38 Amiloride-sensitive sodium channel subunit alpha (Alpha-NaCH) (Epithelial Na(+) channel subunit alpha) (Alpha-ENaC) (Nonvoltage-gated sodium channel 1 subunit alpha) (SCNEA) Neoceratodus forsteri (Australian lungfish) (Ceratodus forsteri) sodium ion transmembrane transport [GO:0035725] GO:0001669; GO:0005737; GO:0015280; GO:0016324; GO:0031514; GO:0034706; GO:0035725 40072 XR_006396376.1 0 0 0 0 7 NA NA NA NA NA NA 40073 XM_044313705.1 342 48 117 229 226 NA NA NA NA NA NA 40074 XM_029355511.2 140 107 67 209 74 Q90481 1.07e-27 Homeobox protein Nkx-2.2a (Homeobox protein NK-2 homolog B-A) Danio rerio (Zebrafish) (Brachydanio rerio) cell differentiation [GO:0030154]; endocrine pancreas development [GO:0031018]; floor plate development [GO:0033504]; floor plate formation [GO:0021508]; glial cell migration [GO:0008347]; motor neuron axon guidance [GO:0008045]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357]; Schwann cell development [GO:0014044]; spinal cord oligodendrocyte cell differentiation [GO:0021529]; spinal cord oligodendrocyte cell fate specification [GO:0021530]; ventral spinal cord interneuron differentiation [GO:0021514] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0008045; GO:0008347; GO:0014044; GO:0021508; GO:0021514; GO:0021529; GO:0021530; GO:0030154; GO:0031018; GO:0033504; GO:0045893 40075 XM_029323595.2 1007 973 976 857 1114 Q5XJE5 7.77e-97 RNA polymerase-associated protein LEO1 Mus musculus (Mouse) endodermal cell fate commitment [GO:0001711]; histone H2B ubiquitination [GO:0033523]; histone monoubiquitination [GO:0010390]; mRNA polyadenylation [GO:0006378]; negative regulation of myeloid cell differentiation [GO:0045638]; positive regulation of mRNA 3'-end processing [GO:0031442]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; stem cell population maintenance [GO:0019827]; transcription elongation by RNA polymerase II promoter [GO:0006368]; Wnt signaling pathway [GO:0016055] GO:0001650; GO:0001711; GO:0005634; GO:0005654; GO:0005813; GO:0006368; GO:0006378; GO:0010390; GO:0016055; GO:0016593; GO:0019827; GO:0031442; GO:0032968; GO:0033523; GO:0045638; GO:1990269 40076 XM_044317019.1 140 4 67 72 45 A7S5D9 2.21e-120 Iodotyrosine deiodinase (EC 1.21.1.1) (Halotyrosine dehalogenase) Nematostella vectensis (Starlet sea anemone) tyrosine metabolic process [GO:0006570] GO:0005886; GO:0006570; GO:0010181; GO:0016491; GO:0140616 40077 XM_044327948.1 32 18 59 64 38 NA NA NA NA NA NA 40078 XR_006397493.1 187 395 131 794 199 NA NA NA NA NA NA 40079 XR_006398030.1 21 2 14 7 10 NA NA NA NA NA NA 40080 XR_003826958.2 8 0 16 22 13 NA NA NA NA NA NA 40081 XR_006393348.1 0 0 0 13 0 NA NA NA NA NA NA 40082 XM_044312167.1 7 0 22 7 9 NA NA NA NA NA NA 40083 XM_044325367.1 1 2 12 946 3 NA NA NA NA NA NA 40084 XM_029335281.2 2195 1733 1850 2020 1743 Q68ED3 2.28e-118 Terminal nucleotidyltransferase 4B (Non-canonical poly(A) RNA polymerase PAPD5) (EC 2.7.7.19) (PAP-associated domain-containing protein 5) (Terminal guanylyltransferase) (EC 2.7.7.-) (Terminal uridylyltransferase 3) (TUTase 3) (Topoisomerase-related function protein 4-2) (TRF4-2) Mus musculus (Mouse) carbohydrate homeostasis [GO:0033500]; cell cycle [GO:0007049]; cell division [GO:0051301]; histone mRNA catabolic process [GO:0071044]; miRNA catabolic process [GO:0010587]; mRNA polyadenylation [GO:0006378]; ncRNA polyadenylation [GO:0043629]; ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process [GO:0043630]; negative regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060212]; negative regulation of telomere maintenance via telomerase [GO:0032211]; positive regulation of 3'-UTR-mediated mRNA stabilization [GO:1905870]; RNA 3' uridylation [GO:0071076]; RNA 3'-end processing [GO:0031123]; rRNA processing [GO:0006364]; sno(s)RNA polyadenylation [GO:0071050] GO:0003677; GO:0003887; GO:0004652; GO:0005730; GO:0005737; GO:0005829; GO:0005886; GO:0006364; GO:0006378; GO:0007049; GO:0010587; GO:0031123; GO:0031499; GO:0032211; GO:0033500; GO:0043629; GO:0043630; GO:0046872; GO:0051301; GO:0060212; GO:0070568; GO:0071044; GO:0071050; GO:0071076; GO:1905870 40085 XM_044316424.1 3 0 7 3 5 NA NA NA NA NA NA 40086 XM_029353250.2 613 384 219 398 1425 NA NA NA NA NA NA 40087 XM_029343266.2 698 560 378 393 282 Q5RD73 1.17e-44 Dual specificity protein phosphatase 3 (EC 3.1.3.16) (EC 3.1.3.48) (Vaccinia H1-related phosphatase) (VHR) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470] GO:0004725; GO:0005634; GO:0006470; GO:0008138; GO:0016311; GO:0016791; GO:0017018 40088 XM_029351148.2 1452 911 604 1626 1532 NA NA NA NA NA NA 40089 XM_044308893.1 52 395 394 127 456 O13146 2.59e-171 Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 1) (Tyrosine-protein kinase receptor ZEK1) Danio rerio (Zebrafish) (Brachydanio rerio) axon guidance [GO:0007411]; cell migration [GO:0016477]; ephrin receptor signaling pathway [GO:0048013]; fasciculation of motor neuron axon [GO:0097156]; fasciculation of sensory neuron axon [GO:0097155]; positive regulation of kinase activity [GO:0033674]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of focal adhesion assembly [GO:0051893]; regulation of GTPase activity [GO:0043087]; regulation of microtubule cytoskeleton organization [GO:0070507]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0004714; GO:0005004; GO:0005005; GO:0005524; GO:0005769; GO:0005886; GO:0007169; GO:0007411; GO:0010717; GO:0016477; GO:0032956; GO:0033674; GO:0043005; GO:0043087; GO:0043235; GO:0048013; GO:0051893; GO:0070507; GO:0097155; GO:0097156 40090 XM_044328754.1 758 411 473 784 580 NA NA NA NA NA NA 40091 XM_029350820.2 235 83 101 185 66 Q5MPA9 8.77e-176 Serine/threonine-protein kinase DCLK2 (EC 2.7.11.1) (CaMK-like CREB regulatory kinase 2) (CL2) (CLICK-II) (CLICK2) (Doublecortin-like and CAM kinase-like 2) (Doublecortin-like kinase 2) Rattus norvegicus (Rat) hippocampus development [GO:0021766]; intracellular signal transduction [GO:0035556]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of protein localization to nucleus [GO:1900181]; peptidyl-serine phosphorylation [GO:0018105]; protein localization to nucleus [GO:0034504]; pyramidal neuron development [GO:0021860] GO:0000226; GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0005856; GO:0008017; GO:0018105; GO:0021766; GO:0021860; GO:0034504; GO:0035556; GO:0106310; GO:1900181 40092 XM_044315867.1 1 0 0 12 0 NA NA NA NA NA NA 40093 XM_044328364.1 127 127 67 137 149 Q9Y5N5 7.01e-67 Methyltransferase N6AMT1 (HemK methyltransferase family member 2) (M.HsaHemK2P) (Lysine N-methyltransferase 9) (EC 2.1.1.-) (Methylarsonite methyltransferase N6AMT1) (EC 2.1.1.-) (Protein N(5)-glutamine methyltransferase) (EC 2.1.1.-) Homo sapiens (Human) arsonoacetate metabolic process [GO:0018872]; chromatin organization [GO:0006325]; DNA methylation on adenine [GO:0032775]; histone lysine methylation [GO:0034968]; methylation [GO:0032259]; peptidyl-glutamine methylation [GO:0018364]; positive regulation of cell growth [GO:0030307]; toxin metabolic process [GO:0009404] GO:0003676; GO:0005634; GO:0005829; GO:0006325; GO:0008276; GO:0008757; GO:0009007; GO:0009404; GO:0018024; GO:0018364; GO:0018872; GO:0030307; GO:0030792; GO:0032259; GO:0032775; GO:0032991; GO:0034968; GO:0035657; GO:0036009; GO:1904047 40094 XM_029327289.2 111 33 38 103 300 O42406 5.92e-114 Homeobox protein SIX3 (CSIX3) (Sine oculis homeobox homolog 3) Gallus gallus (Chicken) apoptotic process involved in development [GO:1902742]; brain development [GO:0007420]; cell proliferation in forebrain [GO:0021846]; epithelial cell maturation [GO:0002070]; eye development [GO:0001654]; forebrain dorsal/ventral pattern formation [GO:0021798]; lens development in camera-type eye [GO:0002088]; lens fiber cell apoptotic process [GO:1990086]; lens fiber cell differentiation [GO:0070306]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of Wnt signaling pathway [GO:0030178]; neuroblast differentiation [GO:0014016]; neuroblast migration [GO:0097402]; optic vesicle morphogenesis [GO:0003404]; pituitary gland development [GO:0021983]; proximal/distal axis specification [GO:0009946]; regulation of cell cycle phase transition [GO:1901987]; regulation of cell population proliferation [GO:0042127]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neural retina development [GO:0061074]; regulation of neuroblast proliferation [GO:1902692]; regulation of transcription by RNA polymerase II [GO:0006357]; telencephalon development [GO:0021537]; telencephalon regionalization [GO:0021978] GO:0000978; GO:0000981; GO:0001228; GO:0001654; GO:0002070; GO:0002088; GO:0003404; GO:0003677; GO:0005634; GO:0005667; GO:0006357; GO:0007420; GO:0009946; GO:0014016; GO:0021537; GO:0021798; GO:0021846; GO:0021978; GO:0021983; GO:0030178; GO:0042127; GO:0045665; GO:0045892; GO:0061074; GO:0070306; GO:0097402; GO:1901987; GO:1902692; GO:1902742; GO:1990086; GO:2000177 40095 XM_044325633.1 42 5 4 5 31 Q8CE96 3.43e-29 tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 (mRNA methyladenosine-N(1)-methyltransferase non-catalytic subunit TRM6) (tRNA(m1A58)-methyltransferase subunit TRM6) (tRNA(m1A58)MTase subunit TRM6) Mus musculus (Mouse) mRNA methylation [GO:0080009]; tRNA methylation [GO:0030488] GO:0005634; GO:0030488; GO:0031515; GO:0080009 40096 XM_044319407.1 20 0 8 0 12 Q09575 1.18e-60 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 40097 XM_044311652.1 0 0 141 125 687 P36887 0 cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11) Sus scrofa (Pig) cellular response to heat [GO:0034605]; negative regulation of meiotic cell cycle process involved in oocyte maturation [GO:1904145]; protein phosphorylation [GO:0006468] GO:0001669; GO:0004674; GO:0004679; GO:0004691; GO:0005524; GO:0005634; GO:0005737; GO:0005739; GO:0005886; GO:0006468; GO:0034605; GO:0036126; GO:0042585; GO:0048471; GO:0106310; GO:1904145 40098 XM_029337642.2 0 5 6 1 20 NA NA NA NA NA NA 40099 XM_029356567.2 51 0 18 47 49 NA NA NA NA NA NA 40100 XM_029326035.2 142 115 17 127 3 Q8NDA2 1.35e-24 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 40101 XM_029333244.2 48 48 16 0 16 NA NA NA NA NA NA 40102 XR_003826771.2 0 9 0 4 1 NA NA NA NA NA NA 40103 XM_029354381.2 74 86 25 36 66 NA NA NA NA NA NA 40104 XM_044321309.1 294 20 57 267 25 NA NA NA NA NA NA 40105 XM_044325495.1 0 0 4 2 9 NA NA NA NA NA NA 40106 XM_029357461.2 0 43 60 88 112 NA NA NA NA NA NA 40107 XM_029339317.2 0 61 0 0 2734 Q8WPW2 3.56e-148 Pyridoxal 5'-phosphate synthase subunit SNZERR (PLP synthase subunit SNZERR) (EC 4.3.3.6) (Ethylene response protein) (PDX1) Suberites domuncula (Sponge) pyridoxal phosphate biosynthetic process [GO:0042823] GO:0036381; GO:0042823 40108 XM_029355411.2 0 9 0 19 0 NA NA NA NA NA NA 40109 XM_044316418.1 11 25 13 21 8 NA NA NA NA NA NA 40110 XM_044310955.1 358 12 125 119 314 B8V7S0 9.34e-64 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 40111 XM_029341341.2 27 62 41 79 67 NA NA NA NA NA NA 40112 XR_003827748.2 0 20 0 0 19 NA NA NA NA NA NA 40113 XM_044324567.1 400 329 202 434 354 A2AGH6 0 Mediator of RNA polymerase II transcription subunit 12 (Mediator complex subunit 12) (OPA-containing protein) (Thyroid hormone receptor-associated protein complex 230 kDa component) (Trap230) (Trinucleotide repeat-containing gene 11 protein) Mus musculus (Mouse) axis elongation involved in somitogenesis [GO:0090245]; embryonic brain development [GO:1990403]; embryonic neurocranium morphogenesis [GO:0048702]; embryonic organ development [GO:0048568]; endoderm development [GO:0007492]; heart development [GO:0007507]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; oligodendrocyte development [GO:0014003]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; post-anal tail morphogenesis [GO:0036342]; protein ubiquitination [GO:0016567]; Schwann cell development [GO:0014044]; somatic stem cell population maintenance [GO:0035019]; somitogenesis [GO:0001756]; spinal cord development [GO:0021510]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0000151; GO:0000978; GO:0001756; GO:0001843; GO:0003682; GO:0003712; GO:0003713; GO:0005634; GO:0005654; GO:0007492; GO:0007507; GO:0008013; GO:0008022; GO:0014003; GO:0014044; GO:0016567; GO:0016592; GO:0019904; GO:0021510; GO:0021915; GO:0035019; GO:0036342; GO:0045893; GO:0045944; GO:0046966; GO:0048568; GO:0048702; GO:0060071; GO:0060261; GO:0061630; GO:0090245; GO:1990403 40114 XM_029337056.2 479 63 210 259 175 Q8IVH2 2.64e-75 Forkhead box protein P4 (Fork head-related protein-like A) Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000785; GO:0000978; GO:0000981; GO:0001227; GO:0005634; GO:0006357; GO:0046872 40115 XM_044318652.1 5 0 3 10 27 O75899 1.33e-26 Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51) (HG20) Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway [GO:0007186]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; neuron-glial cell signaling [GO:0150099]; synaptic transmission, GABAergic [GO:0051932] GO:0004888; GO:0004965; GO:0005737; GO:0005886; GO:0007186; GO:0007193; GO:0007194; GO:0007214; GO:0007268; GO:0038039; GO:0043005; GO:0045211; GO:0046982; GO:0051932; GO:0150099; GO:1902710; GO:1902712 40116 XM_044325648.1 2277 116 1812 181 627 O95497 4.54e-135 Pantetheinase (EC 3.5.1.92) (Pantetheine hydrolase) (Tiff66) (Vascular non-inflammatory molecule 1) (Vanin-1) Homo sapiens (Human) acute inflammatory response [GO:0002526]; cell-cell adhesion [GO:0098609]; chronic inflammatory response [GO:0002544]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; pantothenate metabolic process [GO:0015939]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of T cell differentiation in thymus [GO:0033089]; response to oxidative stress [GO:0006979] GO:0002526; GO:0002544; GO:0005576; GO:0005886; GO:0006954; GO:0006979; GO:0015939; GO:0016020; GO:0017159; GO:0033089; GO:0035577; GO:0045087; GO:0098609; GO:1902177 40117 XR_003824892.2 22 86 83 100 522 NA NA NA NA NA NA 40118 XM_029345053.2 601 382 255 407 397 O95376 9.32e-180 E3 ubiquitin-protein ligase ARIH2 (ARI-2) (Protein ariadne-2 homolog) (EC 2.3.2.31) (RING-type E3 ubiquitin transferase ARIH2) (Triad1 protein) Homo sapiens (Human) developmental cell growth [GO:0048588]; hematopoietic stem cell proliferation [GO:0071425]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000151; GO:0000209; GO:0004842; GO:0005634; GO:0005654; GO:0005737; GO:0006511; GO:0008270; GO:0016567; GO:0031624; GO:0032436; GO:0048588; GO:0061630; GO:0070534; GO:0070936; GO:0071425; GO:1903955 40119 XM_029336869.2 8 0 1 36 12 NA NA NA NA NA NA 40120 XM_044315008.1 48 2 62 38 140 P14381 6.73e-54 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 40121 XM_044315008.1 48 2 62 38 140 P14381 6.73e-54 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 40122 XM_029355626.2 233 941 426 700 1093 P25205 0 DNA replication licensing factor MCM3 (EC 3.6.4.12) (DNA polymerase alpha holoenzyme-associated protein P1) (P1-MCM3) (RLF subunit beta) (p102) Homo sapiens (Human) DNA replication initiation [GO:0006270]; DNA strand elongation involved in DNA replication [GO:0006271]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via break-induced replication [GO:0000727]; mitotic DNA replication initiation [GO:1902975]; regulation of DNA-templated DNA replication initiation [GO:0030174] GO:0000727; GO:0000781; GO:0003677; GO:0003697; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0005658; GO:0005813; GO:0006268; GO:0006270; GO:0006271; GO:0016020; GO:0016887; GO:0030174; GO:0042555; GO:0048471; GO:0071162; GO:1902975 40123 XM_044311805.1 123 80 22 51 55 NA NA NA NA NA NA 40124 XM_029331114.2 136 49 15 102 109 NA NA NA NA NA NA 40125 XR_006394305.1 6 0 0 0 5 NA NA NA NA NA NA 40126 XM_044317364.1 0 0 0 272 2 Q9Y4G6 0 Talin-2 Homo sapiens (Human) cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-cell junction assembly [GO:0007043] GO:0001726; GO:0003779; GO:0005178; GO:0005198; GO:0005200; GO:0005737; GO:0005886; GO:0005925; GO:0007043; GO:0007155; GO:0015629; GO:0045202; GO:0051015; GO:0098609 40127 XM_029357381.2 48 34 10 75 85 Q9VUL9 1.15e-38 Glycoprotein 3-alpha-L-fucosyltransferase A (EC 2.4.1.214) (Core alpha-(1,3)-fucosyltransferase) Drosophila melanogaster (Fruit fly) fucosylation [GO:0036065]; N-glycan fucosylation [GO:0036071]; nervous system development [GO:0007399]; protein glycosylation [GO:0006486] GO:0005797; GO:0006486; GO:0007399; GO:0008417; GO:0018392; GO:0032580; GO:0036065; GO:0036071; GO:0046920 40128 XM_044313347.1 37 68 16 17 5 NA NA NA NA NA NA 40129 XM_029339164.2 131 95 37 78 66 Q55A09 4.23e-29 Probable serine/threonine-protein kinase DDB_G0272254 (EC 2.7.11.1) Dictyostelium discoideum (Social amoeba) protein phosphorylation [GO:0006468]; signal transduction [GO:0007165] GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0006468; GO:0007165; GO:0016020; GO:0106310 40130 XR_006392263.1 0 0 12 0 67 NA NA NA NA NA NA 40131 XM_029358448.2 125 149 102 145 185 NA NA NA NA NA NA 40132 XM_044308257.1 328 192 295 386 682 Q562C7 3.09e-130 Pumilio homolog 3 Rattus norvegicus (Rat) regulation of protein ADP-ribosylation [GO:0010835]; regulation of translation [GO:0006417] GO:0003677; GO:0003729; GO:0005654; GO:0005694; GO:0005730; GO:0005783; GO:0006417; GO:0010835 40133 XM_029327070.2 60 56 19 44 50 A0JPI9 1.23e-75 Leucine-rich repeat-containing protein 74A (Leucine-rich repeat-containing protein 74) Rattus norvegicus (Rat) NA NA 40134 XM_029349750.2 2235 1893 1236 1939 1429 Q9ES46 9.75e-93 Beta-parvin Mus musculus (Mouse) actin cytoskeleton reorganization [GO:0031532]; cell projection assembly [GO:0030031]; establishment or maintenance of cell polarity [GO:0007163]; establishment or maintenance of cell polarity regulating cell shape [GO:0071963]; lamellipodium assembly [GO:0030032]; substrate adhesion-dependent cell spreading [GO:0034446] GO:0003779; GO:0005737; GO:0005886; GO:0005925; GO:0007163; GO:0015629; GO:0030018; GO:0030027; GO:0030031; GO:0030032; GO:0031532; GO:0034446; GO:0071963 40135 XR_006394285.1 0 0 0 7 4 NA NA NA NA NA NA 40136 XM_044312881.1 507 346 210 317 141 Q5RB83 4.45e-88 Phosphoserine phosphatase (PSP) (PSPase) (EC 3.1.3.3) (O-phosphoserine phosphohydrolase) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) L-serine biosynthetic process [GO:0006564]; L-serine metabolic process [GO:0006563] GO:0000287; GO:0005829; GO:0006563; GO:0006564; GO:0036424 40137 XR_006396741.1 16 64 31 38 33 NA NA NA NA NA NA 40138 XR_006396612.1 283 49 207 4 4 NA NA NA NA NA NA 40139 XM_044324240.1 353 351 142 335 184 NA NA NA NA NA NA 40140 XM_029344299.2 11 1 18 13 44 B3DK16 4.31e-72 Polycomb group RING finger protein 5-A Danio rerio (Zebrafish) (Brachydanio rerio) histone H2A-K119 monoubiquitination [GO:0036353]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0006357; GO:0031519; GO:0035102; GO:0036353; GO:0046872 40141 XM_044319250.1 214 66 34 214 88 Q7RTR2 1.49e-30 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 40142 XM_044325381.1 49 47 0 0 56 P70057 2.02e-68 Potassium voltage-gated channel subfamily KQT member 1 (IKs producing slow voltage-gated potassium channel subunit alpha xKvLQT1) (KQT-like 1) (Voltage-gated potassium channel subunit Kv7.1) Xenopus laevis (African clawed frog) inner ear development [GO:0048839]; intestinal absorption [GO:0050892]; membrane repolarization [GO:0086009]; regulation of gastric acid secretion [GO:0060453]; regulation of ion transmembrane transport [GO:0034765]; renal absorption [GO:0070293] GO:0005249; GO:0005251; GO:0005516; GO:0005546; GO:0005737; GO:0005783; GO:0005886; GO:0008076; GO:0015271; GO:0016323; GO:0030659; GO:0034702; GO:0034765; GO:0045121; GO:0048839; GO:0050892; GO:0060453; GO:0070293; GO:0086009 40143 XM_044328730.1 2 0 25 6 88 NA NA NA NA NA NA 40144 XM_029338041.2 881 619 0 727 607 Q9FN03 8.85e-44 Ultraviolet-B receptor UVR8 (Protein UV-B RESISTANCE 8) (RCC1 domain-containing protein UVR8) Arabidopsis thaliana (Mouse-ear cress) entrainment of circadian clock [GO:0009649]; response to UV [GO:0009411]; response to UV-B [GO:0010224] GO:0000785; GO:0003682; GO:0005085; GO:0005634; GO:0005829; GO:0009411; GO:0009536; GO:0009649; GO:0009881; GO:0010224; GO:0042802; GO:0042803 40145 XM_029338041.2 881 619 0 727 607 Q9FN03 8.87e-29 Ultraviolet-B receptor UVR8 (Protein UV-B RESISTANCE 8) (RCC1 domain-containing protein UVR8) Arabidopsis thaliana (Mouse-ear cress) entrainment of circadian clock [GO:0009649]; response to UV [GO:0009411]; response to UV-B [GO:0010224] GO:0000785; GO:0003682; GO:0005085; GO:0005634; GO:0005829; GO:0009411; GO:0009536; GO:0009649; GO:0009881; GO:0010224; GO:0042802; GO:0042803 40146 XM_029338041.2 881 619 0 727 607 Q9FN03 2.41e-22 Ultraviolet-B receptor UVR8 (Protein UV-B RESISTANCE 8) (RCC1 domain-containing protein UVR8) Arabidopsis thaliana (Mouse-ear cress) entrainment of circadian clock [GO:0009649]; response to UV [GO:0009411]; response to UV-B [GO:0010224] GO:0000785; GO:0003682; GO:0005085; GO:0005634; GO:0005829; GO:0009411; GO:0009536; GO:0009649; GO:0009881; GO:0010224; GO:0042802; GO:0042803 40147 XM_044320492.1 4317 1658 1719 1211 1809 Q9UBM8 1.5e-61 Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C (EC 2.4.1.145) (N-acetylglucosaminyltransferase IV homolog) (hGnT-IV-H) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVc) (GlcNAc-T IVc) (GnT-IVc) (N-acetylglucosaminyltransferase IVc) (UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVc) Homo sapiens (Human) protein N-linked glycosylation [GO:0006487]; viral protein processing [GO:0019082] GO:0000139; GO:0006487; GO:0008375; GO:0008454; GO:0019082; GO:0046872 40148 XR_006396023.1 17 65 43 118 115 NA NA NA NA NA NA 40149 XM_029334875.2 326 100 320 483 252 O43451 0 Maltase-glucoamylase (Alpha-1,4-glucosidase) (EC 3.2.1.20) Homo sapiens (Human) dextrin catabolic process [GO:1901027]; maltose catabolic process [GO:0000025]; starch catabolic process [GO:0005983] GO:0000025; GO:0003824; GO:0004339; GO:0004553; GO:0004558; GO:0005886; GO:0005983; GO:0016160; GO:0016324; GO:0030246; GO:0032450; GO:0070062; GO:0070821; GO:0101003; GO:1901027 40150 XM_029334875.2 326 100 320 483 252 O43451 0 Maltase-glucoamylase (Alpha-1,4-glucosidase) (EC 3.2.1.20) Homo sapiens (Human) dextrin catabolic process [GO:1901027]; maltose catabolic process [GO:0000025]; starch catabolic process [GO:0005983] GO:0000025; GO:0003824; GO:0004339; GO:0004553; GO:0004558; GO:0005886; GO:0005983; GO:0016160; GO:0016324; GO:0030246; GO:0032450; GO:0070062; GO:0070821; GO:0101003; GO:1901027 40151 XM_029334875.2 326 100 320 483 252 O43451 0 Maltase-glucoamylase (Alpha-1,4-glucosidase) (EC 3.2.1.20) Homo sapiens (Human) dextrin catabolic process [GO:1901027]; maltose catabolic process [GO:0000025]; starch catabolic process [GO:0005983] GO:0000025; GO:0003824; GO:0004339; GO:0004553; GO:0004558; GO:0005886; GO:0005983; GO:0016160; GO:0016324; GO:0030246; GO:0032450; GO:0070062; GO:0070821; GO:0101003; GO:1901027 40152 XM_029350506.2 155 130 42 115 38 Q66X19 7.42e-41 NACHT, LRR and PYD domains-containing protein 4E (NALP-epsilon) Mus musculus (Mouse) inflammatory response [GO:0006954]; regulation of inflammatory response [GO:0050727] GO:0005524; GO:0005737; GO:0006954; GO:0050727 40153 XM_029357549.2 1304 1390 894 2321 2353 Q496Y0 1.56e-130 LON peptidase N-terminal domain and RING finger protein 3 (RING finger protein 127) Homo sapiens (Human) NA GO:0005737; GO:0046872; GO:0061630 40154 XM_044310904.1 4 0 14 0 0 NA NA NA NA NA NA 40155 XR_006394607.1 20 0 0 11 0 NA NA NA NA NA NA 40156 XM_029348094.2 0 12 0 14 12 O89103 3.4e-21 Complement component C1q receptor (C1q/MBL/SPA receptor) (C1qR(p)) (C1qRp) (Cell surface antigen AA4) (Complement component 1 q subcomponent receptor 1) (Lymphocyte antigen 68) (Ly-68) (CD antigen CD93) Mus musculus (Mouse) cell-cell adhesion [GO:0098609] GO:0001849; GO:0005509; GO:0005886; GO:0009986; GO:0030246; GO:0031410; GO:0098609 40157 XM_029337683.2 9963 9411 9262 9781 7779 Q6GVM3 2.14e-48 Eukaryotic translation initiation factor 1A, Y-chromosomal (eIF-1A Y isoform) (Eukaryotic translation initiation factor 4C) (eIF-4C) Pan troglodytes (Chimpanzee) translational initiation [GO:0006413] GO:0003723; GO:0003743; GO:0005737; GO:0006413 40158 XM_029328671.2 0 68 0 0 29 NA NA NA NA NA NA 40159 XR_006396579.1 0 0 20 0 0 NA NA NA NA NA NA 40160 XM_044313015.1 20 50 116 81 95 P24524 4.78e-45 Glycine receptor subunit alpha-3 Rattus norvegicus (Rat) cellular response to amino acid stimulus [GO:0071230]; cellular response to ethanol [GO:0071361]; cellular response to zinc ion [GO:0071294]; chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; neuropeptide signaling pathway [GO:0007218]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; protein homooligomerization [GO:0051260]; regulation of membrane potential [GO:0042391]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amino acid [GO:0043200]; signal transduction [GO:0007165]; synaptic transmission, glycinergic [GO:0060012] GO:0004888; GO:0005231; GO:0005886; GO:0007165; GO:0007218; GO:0007268; GO:0016594; GO:0016934; GO:0016935; GO:0022852; GO:0030425; GO:0030594; GO:0034220; GO:0042391; GO:0042734; GO:0043005; GO:0043200; GO:0043204; GO:0045202; GO:0046872; GO:0050877; GO:0051260; GO:0060012; GO:0071230; GO:0071294; GO:0071361; GO:0098690; GO:0098793; GO:0098978; GO:0098982; GO:0099171; GO:0099634; GO:1902476; GO:1904315; GO:2000300 40161 XM_029350047.2 1209 816 422 1168 1329 Q12791 0 Calcium-activated potassium channel subunit alpha-1 (BK channel) (BKCA alpha) (Calcium-activated potassium channel, subfamily M subunit alpha-1) (K(VCA)alpha) (KCa1.1) (Maxi K channel) (MaxiK) (Slo-alpha) (Slo1) (Slowpoke homolog) (Slo homolog) (hSlo) Homo sapiens (Human) cellular potassium ion homeostasis [GO:0030007]; micturition [GO:0060073]; negative regulation of cell volume [GO:0045794]; positive regulation of apoptotic process [GO:0043065]; potassium ion transport [GO:0006813]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; relaxation of vascular associated smooth muscle [GO:0060087]; response to calcium ion [GO:0051592]; response to carbon monoxide [GO:0034465]; response to hypoxia [GO:0001666]; response to osmotic stress [GO:0006970]; smooth muscle contraction involved in micturition [GO:0060083] GO:0001666; GO:0003779; GO:0005249; GO:0005886; GO:0005901; GO:0006813; GO:0006970; GO:0008076; GO:0015269; GO:0016020; GO:0016324; GO:0030007; GO:0034465; GO:0034765; GO:0042391; GO:0042802; GO:0043065; GO:0045211; GO:0045794; GO:0046872; GO:0051592; GO:0060072; GO:0060073; GO:0060083; GO:0060087 40162 XM_044325806.1 0 0 24 98 4 Q09575 1.96e-40 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 40163 XM_029325385.2 0 49 0 0 87 NA NA NA NA NA NA 40164 XM_044319307.1 1019 533 539 770 800 Q148V7 0 RAB11-binding protein RELCH (LisH domain and HEAT repeat-containing protein KIAA1468) (RAB11-binding protein containing LisH, coiled-coil, and HEAT repeats) Mus musculus (Mouse) intracellular cholesterol transport [GO:0032367] GO:0005802; GO:0032367; GO:0055037 40165 XM_044316982.1 2044 1538 1258 1559 1775 B1H1P9 7.59e-81 Lysosomal acid phosphatase (LAP) (EC 3.1.3.2) Xenopus laevis (African clawed frog) NA GO:0003993; GO:0005765; GO:0043202 40166 XR_006395305.1 12 0 0 4 1 NA NA NA NA NA NA 40167 XM_044321146.1 0 0 0 0 36 Q9NYT0 1.28e-45 Pleckstrin-2 Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; intracellular signal transduction [GO:0035556]; positive regulation of plasma membrane bounded cell projection assembly [GO:0120034] GO:0005737; GO:0005856; GO:0005886; GO:0031258; GO:0031532; GO:0032266; GO:0035556; GO:0043325; GO:0080025; GO:0120034 40168 XM_044309261.1 4 1 4 0 6 NA NA NA NA NA NA 40169 XM_029355182.2 981 900 214 1042 557 P52046 2.22e-24 Short-chain-enoyl-CoA hydratase (EC 4.2.1.150) (3-hydroxybutyryl-CoA dehydratase) (Crotonase) Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787) butyrate metabolic process [GO:0019605] GO:0016829; GO:0019605 40170 XR_003828393.2 0 0 0 0 36 NA NA NA NA NA NA 40171 XR_006392028.1 2 1 12 2 23 NA NA NA NA NA NA 40172 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 0 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40173 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 0 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40174 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 0 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40175 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 0 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40176 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 0 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40177 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 0 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40178 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 0 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40179 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 0 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40180 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 0 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40181 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 0 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40182 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 0 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40183 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 0 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40184 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 0 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40185 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 8.72e-175 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40186 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 3.27e-173 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40187 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 1.11e-143 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40188 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 1.17e-143 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40189 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 1.13e-137 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40190 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 3.66e-131 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40191 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 9.24e-128 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40192 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 4.53e-107 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40193 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 9.19e-105 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40194 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 6.34e-103 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40195 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 9.28e-98 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40196 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 1.59e-88 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40197 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 1.25e-86 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40198 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 4.46e-84 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40199 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 4.81e-81 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40200 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 8.96e-79 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40201 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 4.17e-78 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40202 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 2.8e-74 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40203 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 4.37e-72 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40204 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 2.25e-71 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40205 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 6.28e-71 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40206 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 6.27e-68 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40207 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 1.19e-66 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40208 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 1.37e-64 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40209 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 1.44e-63 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40210 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 3.32e-62 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40211 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 3.27e-61 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40212 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 5.53e-58 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40213 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 8.91e-58 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40214 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 4.31e-54 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40215 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 6.39e-54 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40216 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 4.61e-51 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40217 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 5.19e-50 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40218 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 6.56e-50 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40219 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 8.15e-50 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40220 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 7.91e-45 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40221 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 5.8e-39 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40222 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 4.84e-38 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40223 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 1.89e-36 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40224 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 2.1e-35 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40225 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 3.86e-35 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40226 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 4.94e-33 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40227 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 3.45e-32 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40228 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 4.85e-30 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40229 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 8.63e-30 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40230 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 2.66e-29 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40231 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 2.56e-28 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40232 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 8.17e-28 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40233 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 1.03e-27 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40234 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 2.51e-26 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40235 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 7.77e-25 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40236 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 9.03e-25 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40237 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 1.66e-24 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40238 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 4.64e-24 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40239 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 6.59e-24 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40240 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 8.32e-24 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40241 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 1.22e-23 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40242 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 5.45e-23 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40243 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 6.49e-23 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40244 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 7.36e-23 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40245 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 2.04e-22 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40246 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 4.43e-22 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40247 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 7.08e-22 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40248 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 1.86e-21 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40249 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 1.99e-21 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40250 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 2.17e-21 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40251 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 2.81e-21 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40252 XM_044316478.1 6725 4273 4592 10644 9505 Q8WZ42 9.5e-21 Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) Homo sapiens (Human) cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941] GO:0000794; GO:0002020; GO:0003300; GO:0004674; GO:0004713; GO:0005509; GO:0005516; GO:0005524; GO:0005576; GO:0005829; GO:0005865; GO:0006936; GO:0006941; GO:0007076; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0031433; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0070062; GO:0097493; GO:0106310; GO:1990733 40253 XM_044310371.1 9 0 1 4 0 NA NA NA NA NA NA 40254 XM_044316774.1 94 14 47 37 43 NA NA NA NA NA NA 40255 XR_006398169.1 240 475 333 416 429 NA NA NA NA NA NA 40256 XM_044317623.1 1226 975 893 1570 1947 A2AUY4 3.62e-98 Bromodomain adjacent to zinc finger domain protein 2B Mus musculus (Mouse) NA GO:0003677; GO:0005634; GO:0046872 40257 XM_044317623.1 1226 975 893 1570 1947 A2AUY4 2.78e-43 Bromodomain adjacent to zinc finger domain protein 2B Mus musculus (Mouse) NA GO:0003677; GO:0005634; GO:0046872 40258 XM_044312478.1 0 7 0 0 0 NA NA NA NA NA NA 40259 XM_029330217.2 170 117 12 150 37 A5D7U4 2.09e-49 Amiloride-sensitive sodium channel subunit beta (Beta-NaCH) (Epithelial Na(+) channel subunit beta) (Beta-ENaC) (Nonvoltage-gated sodium channel 1 subunit beta) (SCNEB) Bos taurus (Bovine) aldosterone metabolic process [GO:0032341]; artery smooth muscle contraction [GO:0014824]; cellular response to acidic pH [GO:0071468]; cellular response to aldosterone [GO:1904045]; cellular response to amiloride [GO:0036254]; cellular sodium ion homeostasis [GO:0006883]; epithelial fluid transport [GO:0042045]; erythrocyte homeostasis [GO:0034101]; gene expression [GO:0010467]; leukocyte activation involved in inflammatory response [GO:0002269]; mucus secretion [GO:0070254]; multicellular organism growth [GO:0035264]; multicellular organismal water homeostasis [GO:0050891]; neutrophil activation involved in immune response [GO:0002283]; neutrophil-mediated killing of bacterium [GO:0070944]; potassium ion homeostasis [GO:0055075]; response to food [GO:0032094]; response to xenobiotic stimulus [GO:0009410]; sensory perception of taste [GO:0050909]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725]; urea homeostasis [GO:0097274] GO:0002269; GO:0002283; GO:0005886; GO:0006883; GO:0009410; GO:0009897; GO:0010467; GO:0014824; GO:0015280; GO:0016324; GO:0030659; GO:0032094; GO:0032341; GO:0034101; GO:0034706; GO:0035264; GO:0035725; GO:0036254; GO:0042045; GO:0050699; GO:0050891; GO:0050909; GO:0055075; GO:0070062; GO:0070254; GO:0070944; GO:0071468; GO:0097274; GO:0098719; GO:1904045 40260 XM_029356988.2 0 5 10 0 0 P30975 1.35e-21 Tachykinin-like peptides receptor 99D (Tachykinin-like receptor at 99D) (dTKR) Drosophila melanogaster (Fruit fly) detection of chemical stimulus involved in sensory perception of smell [GO:0050911]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; neuropeptide signaling pathway [GO:0007218]; olfactory behavior [GO:0042048]; positive regulation of sensory perception of pain [GO:1904058]; tachykinin receptor signaling pathway [GO:0007217] GO:0004995; GO:0005886; GO:0007186; GO:0007217; GO:0007218; GO:0008188; GO:0016020; GO:0042048; GO:0050805; GO:0050911; GO:1904058 40261 XM_044314436.1 129 0 50 0 122 NA NA NA NA NA NA 40262 XR_006397169.1 162 98 75 121 265 NA NA NA NA NA NA 40263 XM_029339033.2 155 135 130 148 126 Q9FN03 4e-36 Ultraviolet-B receptor UVR8 (Protein UV-B RESISTANCE 8) (RCC1 domain-containing protein UVR8) Arabidopsis thaliana (Mouse-ear cress) entrainment of circadian clock [GO:0009649]; response to UV [GO:0009411]; response to UV-B [GO:0010224] GO:0000785; GO:0003682; GO:0005085; GO:0005634; GO:0005829; GO:0009411; GO:0009536; GO:0009649; GO:0009881; GO:0010224; GO:0042802; GO:0042803 40264 XM_029339033.2 155 135 130 148 126 Q9FN03 4.47e-33 Ultraviolet-B receptor UVR8 (Protein UV-B RESISTANCE 8) (RCC1 domain-containing protein UVR8) Arabidopsis thaliana (Mouse-ear cress) entrainment of circadian clock [GO:0009649]; response to UV [GO:0009411]; response to UV-B [GO:0010224] GO:0000785; GO:0003682; GO:0005085; GO:0005634; GO:0005829; GO:0009411; GO:0009536; GO:0009649; GO:0009881; GO:0010224; GO:0042802; GO:0042803 40265 XM_029339033.2 155 135 130 148 126 Q9FN03 8.46e-32 Ultraviolet-B receptor UVR8 (Protein UV-B RESISTANCE 8) (RCC1 domain-containing protein UVR8) Arabidopsis thaliana (Mouse-ear cress) entrainment of circadian clock [GO:0009649]; response to UV [GO:0009411]; response to UV-B [GO:0010224] GO:0000785; GO:0003682; GO:0005085; GO:0005634; GO:0005829; GO:0009411; GO:0009536; GO:0009649; GO:0009881; GO:0010224; GO:0042802; GO:0042803 40266 XM_029352389.2 239 1130 570 752 1978 NA NA NA NA NA NA 40267 XM_044327723.1 1747 1334 1031 1928 1521 Q6PB44 6.01e-159 Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) Mus musculus (Mouse) cilium assembly [GO:0060271]; early endosome to late endosome transport [GO:0045022]; endocytic recycling [GO:0032456]; negative regulation of epithelial cell migration [GO:0010633]; positive regulation of adherens junction organization [GO:1903393]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of homophilic cell adhesion [GO:1903387]; positive regulation of Wnt protein secretion [GO:0061357]; protein dephosphorylation [GO:0006470]; protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] GO:0004725; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005829; GO:0006470; GO:0010633; GO:0016604; GO:0019901; GO:0032456; GO:0036064; GO:0043162; GO:0043231; GO:0043328; GO:0045022; GO:0060271; GO:0061357; GO:1903387; GO:1903393; GO:2000643 40268 XM_044327723.1 1747 1334 1031 1928 1521 Q6PB44 3.1e-53 Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) Mus musculus (Mouse) cilium assembly [GO:0060271]; early endosome to late endosome transport [GO:0045022]; endocytic recycling [GO:0032456]; negative regulation of epithelial cell migration [GO:0010633]; positive regulation of adherens junction organization [GO:1903393]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of homophilic cell adhesion [GO:1903387]; positive regulation of Wnt protein secretion [GO:0061357]; protein dephosphorylation [GO:0006470]; protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] GO:0004725; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005829; GO:0006470; GO:0010633; GO:0016604; GO:0019901; GO:0032456; GO:0036064; GO:0043162; GO:0043231; GO:0043328; GO:0045022; GO:0060271; GO:0061357; GO:1903387; GO:1903393; GO:2000643 40269 XM_029353353.2 11 14 8 14 13 NA NA NA NA NA NA 40270 XM_044316971.1 507 540 565 552 579 NA NA NA NA NA NA 40271 XR_006396026.1 1 9 10 2 24 NA NA NA NA NA NA 40272 XM_044313627.1 37 137 63 81 208 O42412 7.53e-54 Thyroxine 5-deiodinase (EC 1.21.99.3) (5DIII) (DIOIII) (Type 3 DI) (Type III iodothyronine deiodinase) Gallus gallus (Chicken) hormone biosynthetic process [GO:0042446]; thyroid hormone metabolic process [GO:0042403] GO:0004800; GO:0005886; GO:0010008; GO:0033798; GO:0042403; GO:0042446 40273 XM_044315457.1 0 0 0 9 0 NA NA NA NA NA NA 40274 XM_044327934.1 74 121 450 1045 21 NA NA NA NA NA NA 40275 XM_044319964.1 20 0 69 304 0 NA NA NA NA NA NA 40276 XM_029341937.2 77 105 39 231 52 NA NA NA NA NA NA 40277 XM_044313956.1 529 322 10 191 254 NA NA NA NA NA NA 40278 XM_044316834.1 115 60 18 94 11 NA NA NA NA NA NA 40279 XR_006392948.1 41 2 25 5 151 NA NA NA NA NA NA 40280 XM_029335637.2 137 1 150 0 0 Q8K4R9 9.5e-29 Disks large-associated protein 5 (DAP-5) (Discs large homolog 7) (Disks large-associated protein DLG7) (Hepatoma up-regulated protein homolog) (HURP) Mus musculus (Mouse) centrosome localization [GO:0051642]; chromosome segregation [GO:0007059]; kinetochore assembly [GO:0051382]; mitotic spindle organization [GO:0007052]; regulation of mitotic cell cycle [GO:0007346]; signaling [GO:0023052] GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0007052; GO:0007059; GO:0007346; GO:0008017; GO:0023052; GO:0031616; GO:0034451; GO:0051382; GO:0051642 40281 XR_006394978.1 212 582 344 351 272 P52758 3.45e-50 2-iminobutanoate/2-iminopropanoate deaminase (EC 3.5.99.10) (14.5 kDa translational inhibitor protein) (hp14.5) (p14.5) (Heat-responsive protein 12) (Reactive intermediate imine deaminase A homolog) (Translation inhibitor L-PSP ribonuclease) (UK114 antigen homolog) Homo sapiens (Human) brain development [GO:0007420]; G1 to G0 transition [GO:0070314]; kidney development [GO:0001822]; L-threonine catabolic process to glycine [GO:0019518]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; mRNA catabolic process [GO:0006402]; mRNA destabilization [GO:0061157]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of translation [GO:0017148]; organonitrogen compound catabolic process [GO:1901565]; response to lipid [GO:0033993]; response to salt [GO:1902074] GO:0001822; GO:0003723; GO:0003729; GO:0005634; GO:0005737; GO:0005739; GO:0005759; GO:0005777; GO:0005829; GO:0006402; GO:0006629; GO:0007420; GO:0016892; GO:0017148; GO:0019239; GO:0019518; GO:0030324; GO:0033993; GO:0036041; GO:0042802; GO:0046914; GO:0050680; GO:0061157; GO:0070062; GO:0070314; GO:0120242; GO:0120243; GO:1901565; GO:1902074 40282 XM_044324777.1 0 30 15 64 19 NA NA NA NA NA NA 40283 XM_029355381.2 0 0 0 0 8 NA NA NA NA NA NA 40284 XM_029328461.2 0 10 0 0 29 NA NA NA NA NA NA 40285 XR_003827264.2 234 62 117 80 0 NA NA NA NA NA NA 40286 XM_029334801.2 2342 2089 1470 1518 1817 A0JM51 2.8e-118 CUGBP Elav-like family member 5 (CELF-5) (Bruno-like protein 5) (CUG-BP- and ETR-3-like factor 5) (RNA-binding protein BRUNOL-5) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) mRNA processing [GO:0006397] GO:0003723; GO:0005634; GO:0005737; GO:0006397 40287 XR_006397454.1 31 0 39 0 0 Q4V8E5 1.43e-28 Major facilitator superfamily domain-containing protein 3 Rattus norvegicus (Rat) NA GO:0015295; GO:0016020 40288 XM_044310437.1 38 52 98 9 136 NA NA NA NA NA NA 40289 XM_029349304.2 58 39 23 117 27 NA NA NA NA NA NA 40290 XM_029343436.2 30 44 3 16 10 Q8CBH5 3.08e-61 Major facilitator superfamily domain-containing protein 6 (Macrophage MHC class I receptor 2) Mus musculus (Mouse) adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590] GO:0002250; GO:0005886; GO:0016020; GO:0032393; GO:0042288; GO:0042590 40291 XM_044318698.1 7 0 0 0 0 NA NA NA NA NA NA 40292 XM_029342214.2 95 0 0 128 0 NA NA NA NA NA NA 40293 XM_044321567.1 0 0 8 0 0 Q96IZ5 7.91e-61 RNA-binding protein 41 (RNA-binding motif protein 41) Homo sapiens (Human) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0005689; GO:0030626; GO:0097157 40294 XM_029334430.2 174 94 137 251 181 NA NA NA NA NA NA 40295 XR_006397727.1 61 24 117 0 24 NA NA NA NA NA NA 40296 XM_029347343.2 31 178 243 237 223 Q8N159 2.3e-92 N-acetylglutamate synthase, mitochondrial (EC 2.3.1.1) (Amino-acid acetyltransferase) [Cleaved into: N-acetylglutamate synthase long form; N-acetylglutamate synthase short form; N-acetylglutamate synthase conserved domain form] Homo sapiens (Human) arginine biosynthetic process [GO:0006526]; glutamate metabolic process [GO:0006536]; urea cycle [GO:0000050] GO:0000050; GO:0004042; GO:0005739; GO:0005759; GO:0006526; GO:0006536; GO:0103045 40297 XM_044325575.1 326 197 161 238 339 Q7TQF2 9.39e-89 F-box only protein 10 Mus musculus (Mouse) apoptotic process [GO:0006915]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0005737; GO:0006511; GO:0006915; GO:0016567; GO:0042981 40298 XM_044325575.1 326 197 161 238 339 Q7TQF2 6.31e-62 F-box only protein 10 Mus musculus (Mouse) apoptotic process [GO:0006915]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0005737; GO:0006511; GO:0006915; GO:0016567; GO:0042981 40299 XM_044322887.1 166 33 56 246 193 Q5UQ13 8.39e-23 Collagen-like protein 2 Acanthamoeba polyphaga mimivirus (APMV) NA GO:0044423 40300 XM_044322887.1 166 33 56 246 193 Q5UQ13 1.14e-21 Collagen-like protein 2 Acanthamoeba polyphaga mimivirus (APMV) NA GO:0044423 40301 XM_044307776.1 7 0 39 10 62 P79134 4.45e-73 Annexin A6 (Annexin VI) (Annexin-6) Bos taurus (Bovine) apoptotic signaling pathway [GO:0097190]; biomineral tissue development [GO:0031214]; calcium ion import [GO:0070509]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; growth plate cartilage chondrocyte differentiation [GO:0003418]; mitochondrial calcium ion homeostasis [GO:0051560]; negative regulation of sequestering of calcium ion [GO:0051283]; neural crest cell migration [GO:0001755]; plasma membrane repair [GO:0001778]; regulation of muscle contraction [GO:0006937] GO:0001725; GO:0001755; GO:0001778; GO:0001786; GO:0003418; GO:0005262; GO:0005509; GO:0005525; GO:0005544; GO:0005737; GO:0005886; GO:0005925; GO:0006816; GO:0006937; GO:0008201; GO:0015276; GO:0015485; GO:0016020; GO:0019899; GO:0030061; GO:0031214; GO:0031982; GO:0035374; GO:0038024; GO:0042470; GO:0042584; GO:0048306; GO:0048471; GO:0051015; GO:0051283; GO:0051560; GO:0070509; GO:0070588; GO:0097190 40302 XM_044307776.1 7 0 39 10 62 P79134 1.46e-38 Annexin A6 (Annexin VI) (Annexin-6) Bos taurus (Bovine) apoptotic signaling pathway [GO:0097190]; biomineral tissue development [GO:0031214]; calcium ion import [GO:0070509]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; growth plate cartilage chondrocyte differentiation [GO:0003418]; mitochondrial calcium ion homeostasis [GO:0051560]; negative regulation of sequestering of calcium ion [GO:0051283]; neural crest cell migration [GO:0001755]; plasma membrane repair [GO:0001778]; regulation of muscle contraction [GO:0006937] GO:0001725; GO:0001755; GO:0001778; GO:0001786; GO:0003418; GO:0005262; GO:0005509; GO:0005525; GO:0005544; GO:0005737; GO:0005886; GO:0005925; GO:0006816; GO:0006937; GO:0008201; GO:0015276; GO:0015485; GO:0016020; GO:0019899; GO:0030061; GO:0031214; GO:0031982; GO:0035374; GO:0038024; GO:0042470; GO:0042584; GO:0048306; GO:0048471; GO:0051015; GO:0051283; GO:0051560; GO:0070509; GO:0070588; GO:0097190 40303 XM_044307776.1 7 0 39 10 62 P79134 9.75e-35 Annexin A6 (Annexin VI) (Annexin-6) Bos taurus (Bovine) apoptotic signaling pathway [GO:0097190]; biomineral tissue development [GO:0031214]; calcium ion import [GO:0070509]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; growth plate cartilage chondrocyte differentiation [GO:0003418]; mitochondrial calcium ion homeostasis [GO:0051560]; negative regulation of sequestering of calcium ion [GO:0051283]; neural crest cell migration [GO:0001755]; plasma membrane repair [GO:0001778]; regulation of muscle contraction [GO:0006937] GO:0001725; GO:0001755; GO:0001778; GO:0001786; GO:0003418; GO:0005262; GO:0005509; GO:0005525; GO:0005544; GO:0005737; GO:0005886; GO:0005925; GO:0006816; GO:0006937; GO:0008201; GO:0015276; GO:0015485; GO:0016020; GO:0019899; GO:0030061; GO:0031214; GO:0031982; GO:0035374; GO:0038024; GO:0042470; GO:0042584; GO:0048306; GO:0048471; GO:0051015; GO:0051283; GO:0051560; GO:0070509; GO:0070588; GO:0097190 40304 XM_044317709.1 8 21 8 0 0 NA NA NA NA NA NA 40305 XM_044324968.1 0 0 14 0 14 P81274 8.73e-32 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 40306 XM_044324968.1 0 0 14 0 14 P81274 9.35e-30 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 40307 XM_044310325.1 56 8 63 118 41 Q80XJ3 4.61e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 40308 XR_006398178.1 10 1 0 6 1 NA NA NA NA NA NA 40309 XM_044324360.1 13 0 0 91 46 NA NA NA NA NA NA 40310 XR_006394788.1 0 21 21 12 100 NA NA NA NA NA NA 40311 XM_044315494.1 195 195 107 213 163 NA NA NA NA NA NA 40312 XM_044315415.1 0 9 5 0 2 NA NA NA NA NA NA 40313 XM_029342525.2 53 24 37 31 32 NA NA NA NA NA NA 40314 XM_029337355.2 1342 1075 724 1175 1269 Q8IWZ8 1.16e-39 SURP and G-patch domain-containing protein 1 (RNA-binding protein RBP) (Splicing factor 4) Homo sapiens (Human) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0003723; GO:0005654; GO:0005681; GO:0006397; GO:0008380 40315 XM_029338569.2 1531 915 1173 941 727 Q9D8X1 1.11e-106 Copper homeostasis protein cutC homolog Mus musculus (Mouse) protein tetramerization [GO:0051262] GO:0005507; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0051262 40316 XM_029356043.2 60 34 44 95 126 NA NA NA NA NA NA 40317 XR_006396079.1 15 20 35 12 36 NA NA NA NA NA NA 40318 XM_044326557.1 14 13 34 32 7 NA NA NA NA NA NA 40319 XM_044308816.1 764 370 211 740 479 Q9VB11 0 Protein unc-80 homolog Drosophila melanogaster (Fruit fly) cation homeostasis [GO:0055080]; locomotor rhythm [GO:0045475] GO:0005261; GO:0030424; GO:0034703; GO:0045475; GO:0055080 40320 XM_044308816.1 764 370 211 740 479 Q9VB11 1.05e-23 Protein unc-80 homolog Drosophila melanogaster (Fruit fly) cation homeostasis [GO:0055080]; locomotor rhythm [GO:0045475] GO:0005261; GO:0030424; GO:0034703; GO:0045475; GO:0055080 40321 XM_029354498.2 56 83 22 102 84 P97402 2.73e-67 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase (N-acetylglucosaminyltransferase) (EC 2.4.1.150) (I-branching enzyme) (IGNT) (Large I antigen-forming beta-1,6-N-acetylglucosaminyltransferase) Mus musculus (Mouse) maintenance of lens transparency [GO:0036438]; negative regulation of cell-substrate adhesion [GO:0010812]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of protein kinase B signaling [GO:0051897]; post-transcriptional regulation of gene expression [GO:0010608]; protein glycosylation [GO:0006486]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0000139; GO:0005794; GO:0006486; GO:0007179; GO:0008109; GO:0008284; GO:0008375; GO:0010608; GO:0010718; GO:0010812; GO:0030335; GO:0034116; GO:0036438; GO:0051897; GO:0070374 40322 XM_029348288.2 97 71 72 97 74 Q9UKT8 3.22e-124 F-box/WD repeat-containing protein 2 (F-box and WD-40 domain-containing protein 2) (Protein MD6) Homo sapiens (Human) protein modification process [GO:0036211]; proteolysis [GO:0006508] GO:0004842; GO:0005829; GO:0006508; GO:0036211 40323 XM_044321269.1 8 19 7 75 71 NA NA NA NA NA NA 40324 XM_044327071.1 1 0 9 17 34 NA NA NA NA NA NA 40325 XM_029343314.2 108 65 24 73 72 Q8VCC1 8.29e-59 15-hydroxyprostaglandin dehydrogenase [NAD(+)] (15-PGDH) (EC 1.1.1.141) (Eicosanoid/docosanoid dehydrogenase [NAD(+)]) (EC 1.1.1.-, EC 1.1.1.232) (Prostaglandin dehydrogenase 1) Mus musculus (Mouse) ductus arteriosus closure [GO:0097070]; female pregnancy [GO:0007565]; kidney development [GO:0001822]; negative regulation of cell cycle [GO:0045786]; ovulation [GO:0030728]; parturition [GO:0007567]; positive regulation of apoptotic process [GO:0043065]; positive regulation of vascular associated smooth muscle cell proliferation [GO:1904707]; prostaglandin metabolic process [GO:0006693]; regulation of prostaglandin catabolic process [GO:1905828]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; thrombin-activated receptor signaling pathway [GO:0070493]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001822; GO:0004957; GO:0005615; GO:0005654; GO:0005737; GO:0005829; GO:0006693; GO:0007179; GO:0007565; GO:0007567; GO:0016323; GO:0016404; GO:0016616; GO:0030728; GO:0032355; GO:0032496; GO:0042802; GO:0043065; GO:0045471; GO:0045786; GO:0051287; GO:0070403; GO:0070493; GO:0097070; GO:1904707; GO:1905828 40326 XM_044319162.1 0 5 53 2 0 Q7L622 3.08e-32 G2/M phase-specific E3 ubiquitin-protein ligase (EC 2.3.2.26) (G2/M phase-specific HECT-type E3 ubiquitin transferase) Homo sapiens (Human) apoptotic process [GO:0006915] GO:0004842; GO:0005634; GO:0005730; GO:0005794; GO:0005829; GO:0006915; GO:0043231; GO:0046872 40327 XM_029351837.2 715 631 461 722 563 NA NA NA NA NA NA 40328 XM_029332798.2 34 2 13 0 0 Q9I8C7 5.94e-96 Neuronal acetylcholine receptor subunit alpha-10 (Alpha 10 nAChR) (Nicotinic acetylcholine receptor subunit alpha-10) (NACHR alpha-10) Gallus gallus (Chicken) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; response to auditory stimulus [GO:0010996]; signal transduction [GO:0007165] GO:0004888; GO:0005231; GO:0005262; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0010996; GO:0022848; GO:0030594; GO:0034220; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051899; GO:1904315 40329 XR_003826195.2 460 361 166 1211 632 NA NA NA NA NA NA 40330 XM_044315569.1 162 267 57 71 146 NA NA NA NA NA NA 40331 XM_029356509.2 6 2 29 0 32 NA NA NA NA NA NA 40332 XM_029335701.2 611 320 343 405 336 B3DLH6 0 Myoferlin (Fer-1-like protein 3) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) plasma membrane repair [GO:0001778] GO:0001778; GO:0005543; GO:0005901; GO:0030659; GO:0031965; GO:0046872 40333 XR_006394391.1 46 61 0 0 28 Q96AY4 3.45e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 40334 XR_006394391.1 46 61 0 0 28 Q96AY4 7.83e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 40335 XR_006394391.1 46 61 0 0 28 Q96AY4 1.87e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 40336 XR_006394391.1 46 61 0 0 28 Q96AY4 1.18e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 40337 XR_006394391.1 46 61 0 0 28 Q96AY4 1.59e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 40338 XM_029356755.2 0 29 171 0 34 Q8NHP1 2.45e-88 Aflatoxin B1 aldehyde reductase member 4 (EC 1.-.-.-) (AFB1 aldehyde reductase 3) (AFB1-AR 3) (Aldoketoreductase 7-like) Homo sapiens (Human) NA GO:0004033; GO:0005737; GO:0005829; GO:0070062 40339 XM_029356755.2 0 29 171 0 34 Q8NHP1 2.85e-56 Aflatoxin B1 aldehyde reductase member 4 (EC 1.-.-.-) (AFB1 aldehyde reductase 3) (AFB1-AR 3) (Aldoketoreductase 7-like) Homo sapiens (Human) NA GO:0004033; GO:0005737; GO:0005829; GO:0070062 40340 XM_044310695.1 0 10 23 47 23 A3KMX0 0 DNA excision repair protein ERCC-6-like 2 (EC 3.6.4.-) Bos taurus (Bovine) DNA repair [GO:0006281] GO:0003677; GO:0004386; GO:0005524; GO:0005634; GO:0005739; GO:0005815; GO:0006281; GO:0016787; GO:0140658 40341 XM_029336398.2 3163 1554 1687 3495 2431 Q6V4S5 0 Protein sidekick-2 Mus musculus (Mouse) camera-type eye photoreceptor cell differentiation [GO:0060219]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; retina layer formation [GO:0010842]; synapse assembly [GO:0007416] GO:0005886; GO:0007156; GO:0007416; GO:0010842; GO:0045202; GO:0060219 40342 XR_006392212.1 0 2 0 14 35 NA NA NA NA NA NA 40343 XR_006394197.1 27 67 19 83 29 Q6AXK4 7.82e-45 BRISC and BRCA1-A complex member 1 (Mediator of RAP80 interactions and targeting subunit of 40 kDa) (New component of the BRCA1-A complex) Danio rerio (Zebrafish) (Brachydanio rerio) cell division [GO:0051301]; chromatin organization [GO:0006325]; double-strand break repair [GO:0006302]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; positive regulation of DNA repair [GO:0045739]; protein K63-linked deubiquitination [GO:0070536]; response to ionizing radiation [GO:0010212] GO:0005634; GO:0005737; GO:0006302; GO:0006325; GO:0007095; GO:0010212; GO:0016604; GO:0045739; GO:0051301; GO:0070531; GO:0070536; GO:0070552 40344 XM_029348765.2 13 2 0 0 0 Q570Y9 9.37e-53 DEP domain-containing mTOR-interacting protein (DEP domain-containing protein 6) Mus musculus (Mouse) intracellular signal transduction [GO:0035556]; negative regulation of cell size [GO:0045792]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of TOR signaling [GO:0032007]; negative regulation of TORC1 signaling [GO:1904262]; negative regulation of TORC2 signaling [GO:1903940]; regulation of extrinsic apoptotic signaling pathway [GO:2001236] GO:0006469; GO:0032007; GO:0035556; GO:0045792; GO:1903940; GO:1904262; GO:2001236 40345 XM_029352187.2 778 605 495 962 1088 Q9M9E8 1.53e-25 Lysine-specific demethylase JMJ21 (EC 1.14.11.-) (F-box protein JMJ21) (Jumonji domain-containing protein 21) (AtJMJ21) (Protein JUMONJI 21) (Lysine-specific histone demethylase JMJ21) ([histone H3]-trimethyl-L-lysine monodemethylase JMJ21) Arabidopsis thaliana (Mouse-ear cress) NA GO:0005634; GO:0005737; GO:0016491; GO:0046872 40346 XM_029341123.2 500 315 156 343 200 Q8IY57 8.86e-24 YY1-associated factor 2 Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA-templated transcription [GO:0006355] GO:0003677; GO:0003712; GO:0003713; GO:0003714; GO:0005634; GO:0005654; GO:0005829; GO:0006355; GO:0045892; GO:0045893; GO:0046872 40347 XM_044313945.1 0 0 0 0 7 B8VIU6 1.34e-61 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 40348 XM_029339873.2 1018 996 657 910 894 Q9UJW0 4.22e-115 Dynactin subunit 4 (Dyn4) (Dynactin subunit p62) Homo sapiens (Human) NA GO:0000776; GO:0000922; GO:0001725; GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0005868; GO:0005869; GO:0005925; GO:0005938; GO:0030017; GO:0047485 40349 XM_029350886.2 66 150 97 0 21 Q5ZLC6 4.63e-39 Ankyrin repeat domain-containing protein 10 Gallus gallus (Chicken) NA NA 40350 XM_029355310.2 962 624 368 574 485 Q9WTS8 3.11e-73 Ficolin-1 (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin-alpha) (M-ficolin) Rattus norvegicus (Rat) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to virus [GO:0051607]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of RNA biosynthetic process [GO:1902679]; negative regulation of viral entry into host cell [GO:0046597]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of opsonization [GO:1903028]; proteolysis [GO:0006508]; recognition of apoptotic cell [GO:0043654] GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005581; GO:0005615; GO:0006508; GO:0006956; GO:0007186; GO:0030246; GO:0031232; GO:0032757; GO:0038187; GO:0043654; GO:0046597; GO:0046872; GO:0051607; GO:0062023; GO:0097367; GO:1902679; GO:1903028; GO:1905370 40351 XM_029332557.2 2108 1393 1357 1876 1905 P0C6F1 0 Dynein axonemal heavy chain 2 (Axonemal beta dynein heavy chain 2) (Ciliary dynein heavy chain 2) Mus musculus (Mouse) cilium movement [GO:0003341]; cilium-dependent cell motility [GO:0060285]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005524; GO:0005858; GO:0005874; GO:0005929; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0031514; GO:0036126; GO:0036156; GO:0036159; GO:0045505; GO:0051959; GO:0060285 40352 XM_029332557.2 2108 1393 1357 1876 1905 P0C6F1 1.1e-91 Dynein axonemal heavy chain 2 (Axonemal beta dynein heavy chain 2) (Ciliary dynein heavy chain 2) Mus musculus (Mouse) cilium movement [GO:0003341]; cilium-dependent cell motility [GO:0060285]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005524; GO:0005858; GO:0005874; GO:0005929; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0031514; GO:0036126; GO:0036156; GO:0036159; GO:0045505; GO:0051959; GO:0060285 40353 XR_003825498.2 4 0 7 6 23 NA NA NA NA NA NA 40354 XM_029337245.2 598 442 339 537 599 NA NA NA NA NA NA 40355 XR_003826318.2 30 23 3 2 52 NA NA NA NA NA NA 40356 XR_006394337.1 0 0 23 2 40 NA NA NA NA NA NA 40357 XM_044318903.1 1389 0 858 948 1069 Q5RD26 1.04e-44 Heterogeneous nuclear ribonucleoprotein H2 (hnRNP H2) (Heterogeneous nuclear ribonucleoprotein H') (hnRNP H') [Cleaved into: Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed] Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003723; GO:0005654; GO:1990904 40358 XM_029334615.2 4 124 20 11 3 Q8K3Z0 3.25e-30 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 40359 XR_006391814.1 70 367 165 53 427 NA NA NA NA NA NA 40360 XM_029343700.2 28 0 29 21 44 Q94K49 9.06e-40 Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1 (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) epigenetic regulation of gene expression [GO:0040029] GO:0003682; GO:0004518; GO:0005634; GO:0035098; GO:0035102; GO:0040029; GO:0046872 40361 XM_029331821.2 871 467 356 777 900 NA NA NA NA NA NA 40362 XM_044324544.1 345 253 226 279 141 NA NA NA NA NA NA 40363 XM_044320580.1 158 131 105 233 104 NA NA NA NA NA NA 40364 XM_044315045.1 0 0 1 1 16 NA NA NA NA NA NA 40365 XM_029352635.2 503 74 74 219 167 NA NA NA NA NA NA 40366 XM_029335779.2 20 4 27 0 28 NA NA NA NA NA NA 40367 XM_044317263.1 0 0 58 0 0 Q9WYP5 3.01e-61 Myo-inositol 2-dehydrogenase (EC 1.1.1.18) Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) inositol metabolic process [GO:0006020]; NADPH regeneration [GO:0006740] GO:0000166; GO:0006020; GO:0006740; GO:0016491; GO:0050112 40368 XR_006394321.1 28 0 38 19 31 NA NA NA NA NA NA 40369 XM_044319892.1 376 210 103 443 385 Q4V8I4 3.11e-116 Differentially expressed in FDCP 8 homolog (DEF-8) Rattus norvegicus (Rat) lysosome localization [GO:0032418]; positive regulation of bone resorption [GO:0045780]; positive regulation of ruffle assembly [GO:1900029] GO:0032418; GO:0045780; GO:0046872; GO:1900029 40370 XR_003823838.2 21 3 59 9 188 NA NA NA NA NA NA 40371 XM_029357540.2 0 0 0 6 10 O75899 2.82e-116 Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51) (HG20) Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway [GO:0007186]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; neuron-glial cell signaling [GO:0150099]; synaptic transmission, GABAergic [GO:0051932] GO:0004888; GO:0004965; GO:0005737; GO:0005886; GO:0007186; GO:0007193; GO:0007194; GO:0007214; GO:0007268; GO:0038039; GO:0043005; GO:0045211; GO:0046982; GO:0051932; GO:0150099; GO:1902710; GO:1902712 40372 XM_029323931.2 2040 2030 1111 1362 1174 P40307 3.96e-85 Proteasome subunit beta type-2 (Macropain subunit C7-I) (Multicatalytic endopeptidase complex subunit C7-I) (Proteasome component C7-I) Rattus norvegicus (Rat) proteasomal protein catabolic process [GO:0010498]; response to organic cyclic compound [GO:0014070]; response to organonitrogen compound [GO:0010243] GO:0000502; GO:0005634; GO:0005654; GO:0005737; GO:0005839; GO:0010243; GO:0010498; GO:0014070; GO:0019774 40373 XM_029358182.2 2400 2007 1066 2744 2525 C9WPN6 0 Eukaryotic translation initiation factor 2 subunit 3, Y-linked (EC 3.6.5.3) (Eukaryotic translation initiation factor 2 subunit gamma, Y-linked) (eIF-2-gamma Y) Rattus norvegicus (Rat) formation of translation preinitiation complex [GO:0001731] GO:0000049; GO:0001731; GO:0003743; GO:0003924; GO:0005525; GO:0005850 40374 XM_044308772.1 114 40 125 162 88 NA NA NA NA NA NA 40375 XR_006394593.1 6 0 2 0 12 NA NA NA NA NA NA 40376 XR_006393984.1 23 8 43 31 136 NA NA NA NA NA NA 40377 XR_003825450.2 6 18 12 0 94 NA NA NA NA NA NA 40378 XM_044319349.1 3844 2064 1144 2255 1628 Q1RMU2 2.54e-128 Ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.4.19.12) (Deubiquitinating enzyme CYLD) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD) Bos taurus (Bovine) innate immune response [GO:0045087]; necroptotic process [GO:0070266]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-18-mediated signaling pathway [GO:2000493]; negative regulation of JNK cascade [GO:0046329]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of p38MAPK cascade [GO:1903753]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; protein deubiquitination [GO:0016579]; protein K63-linked deubiquitination [GO:0070536]; protein linear deubiquitination [GO:1990108]; regulation of cilium assembly [GO:1902017]; regulation of inflammatory response [GO:0050727]; regulation of intrinsic apoptotic signaling pathway [GO:2001242]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of mitotic cell cycle [GO:0007346]; regulation of necroptotic process [GO:0060544]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt signaling pathway [GO:0016055] GO:0004843; GO:0005813; GO:0005819; GO:0005829; GO:0005881; GO:0006511; GO:0007346; GO:0008270; GO:0010803; GO:0016055; GO:0016579; GO:0019901; GO:0030496; GO:0031234; GO:0032088; GO:0036064; GO:0045087; GO:0046329; GO:0048471; GO:0050727; GO:0050728; GO:0060544; GO:0061578; GO:0070064; GO:0070266; GO:0070507; GO:0070536; GO:0090090; GO:0097542; GO:1901223; GO:1902017; GO:1903753; GO:1990108; GO:2000493; GO:2001238; GO:2001242 40379 XM_029355709.2 305 268 233 298 216 Q7ZXZ2 2.39e-157 U3 small nucleolar RNA-associated protein 15 homolog Xenopus laevis (African clawed frog) rRNA processing [GO:0006364] GO:0005730; GO:0006364 40380 XR_006396790.1 438 35 218 302 146 NA NA NA NA NA NA 40381 XM_044318125.1 6102 2120 514 2508 3252 NA NA NA NA NA NA 40382 XR_003827144.2 85 27 29 8 40 NA NA NA NA NA NA 40383 XR_006396598.1 386 254 350 379 445 NA NA NA NA NA NA 40384 XR_006396091.1 5 9 9 4 2 P07700 4.03e-26 Beta-1 adrenergic receptor (Beta-1 adrenoreceptor) (Beta-1 adrenoceptor) (Beta-T) Meleagris gallopavo (Wild turkey) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; positive regulation of GTPase activity [GO:0043547]; positive regulation of heart contraction [GO:0045823]; regulation of circadian sleep/wake cycle, sleep [GO:0045187] GO:0004940; GO:0005085; GO:0005769; GO:0005886; GO:0016020; GO:0042802; GO:0043547; GO:0045187; GO:0045823; GO:0071880 40385 XR_006396091.1 5 9 9 4 2 P07700 4.03e-26 Beta-1 adrenergic receptor (Beta-1 adrenoreceptor) (Beta-1 adrenoceptor) (Beta-T) Meleagris gallopavo (Wild turkey) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; positive regulation of GTPase activity [GO:0043547]; positive regulation of heart contraction [GO:0045823]; regulation of circadian sleep/wake cycle, sleep [GO:0045187] GO:0004940; GO:0005085; GO:0005769; GO:0005886; GO:0016020; GO:0042802; GO:0043547; GO:0045187; GO:0045823; GO:0071880 40386 XR_006392223.1 0 0 13 3 3 NA NA NA NA NA NA 40387 XM_029327338.2 0 3 8 0 0 NA NA NA NA NA NA 40388 XM_044308752.1 384 213 162 271 12 NA NA NA NA NA NA 40389 XM_029345771.2 454 382 214 482 255 Q9UHD2 2.51e-143 Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1) Homo sapiens (Human) activation of innate immune response [GO:0002218]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; dendritic cell proliferation [GO:0044565]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of gene expression [GO:0010629]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of macroautophagy [GO:0016239]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of xenophagy [GO:1904417]; protein phosphorylation [GO:0006468]; regulation of neuron death [GO:1901214]; regulation of type I interferon production [GO:0032479]; response to virus [GO:0009615]; type I interferon-mediated signaling pathway [GO:0060337] GO:0002218; GO:0003676; GO:0004672; GO:0004674; GO:0005524; GO:0005654; GO:0005737; GO:0005829; GO:0006468; GO:0006954; GO:0007249; GO:0009615; GO:0010629; GO:0016239; GO:0018105; GO:0018107; GO:0019903; GO:0032479; GO:0032481; GO:0032727; GO:0032728; GO:0033138; GO:0042802; GO:0043123; GO:0043231; GO:0044565; GO:0045087; GO:0045944; GO:0050830; GO:0051219; GO:0051607; GO:0060337; GO:0060340; GO:0106310; GO:1901214; GO:1902554; GO:1904417 40390 XM_044329100.1 210 279 271 257 393 Q86YS7 3.13e-170 C2 domain-containing protein 5 (C2 domain-containing phosphoprotein of 138 kDa) Homo sapiens (Human) cellular response to insulin stimulus [GO:0032869]; insulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028]; intracellular protein transmembrane transport [GO:0065002]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of vesicle fusion [GO:0031340]; protein localization to plasma membrane [GO:0072659] GO:0005509; GO:0005544; GO:0005829; GO:0005886; GO:0005938; GO:0010828; GO:0030659; GO:0031340; GO:0032587; GO:0032869; GO:0034451; GO:0038028; GO:0065002; GO:0072659; GO:0090314 40391 XM_044329100.1 210 279 271 257 393 Q86YS7 5.21e-105 C2 domain-containing protein 5 (C2 domain-containing phosphoprotein of 138 kDa) Homo sapiens (Human) cellular response to insulin stimulus [GO:0032869]; insulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028]; intracellular protein transmembrane transport [GO:0065002]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of vesicle fusion [GO:0031340]; protein localization to plasma membrane [GO:0072659] GO:0005509; GO:0005544; GO:0005829; GO:0005886; GO:0005938; GO:0010828; GO:0030659; GO:0031340; GO:0032587; GO:0032869; GO:0034451; GO:0038028; GO:0065002; GO:0072659; GO:0090314 40392 XM_044310196.1 0 45 16 1 11 NA NA NA NA NA NA 40393 XM_029327594.2 1488 1577 1052 957 1010 NA NA NA NA NA NA 40394 XM_029329535.2 35 76 16 100 43 NA NA NA NA NA NA 40395 XM_029352345.2 78 63 67 67 90 Q8IY37 0 Probable ATP-dependent RNA helicase DHX37 (EC 3.6.4.13) (DEAH box protein 37) Homo sapiens (Human) brain development [GO:0007420]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; positive regulation of male gonad development [GO:2000020]; ribosome assembly [GO:0042255]; ribosome biogenesis [GO:0042254] GO:0000462; GO:0003723; GO:0003724; GO:0005524; GO:0005654; GO:0005730; GO:0005737; GO:0007420; GO:0016887; GO:0031965; GO:0034511; GO:0042254; GO:0042255; GO:2000020 40396 XM_029341718.2 1246 0 941 190 0 Q96MU7 1.08e-62 YTH domain-containing protein 1 (Splicing factor YT521) (YT521-B) Homo sapiens (Human) dosage compensation by inactivation of X chromosome [GO:0009048]; in utero embryonic development [GO:0001701]; mRNA alternative polyadenylation [GO:0110104]; mRNA export from nucleus [GO:0006406]; mRNA splice site selection [GO:0006376]; mRNA splicing, via spliceosome [GO:0000398]; post-transcriptional regulation of gene expression [GO:0010608]; primary follicle stage [GO:0048160]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of mRNA splicing, via spliceosome [GO:0048024]; spermatogenesis [GO:0007283] GO:0000381; GO:0000398; GO:0001701; GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0005886; GO:0006376; GO:0006406; GO:0007283; GO:0009048; GO:0010608; GO:0016607; GO:0048024; GO:0048160; GO:0110104; GO:1990247 40397 XM_029346689.2 509 276 333 1071 211 A2AUY4 3.74e-98 Bromodomain adjacent to zinc finger domain protein 2B Mus musculus (Mouse) NA GO:0003677; GO:0005634; GO:0046872 40398 XM_029346689.2 509 276 333 1071 211 A2AUY4 2.06e-43 Bromodomain adjacent to zinc finger domain protein 2B Mus musculus (Mouse) NA GO:0003677; GO:0005634; GO:0046872 40399 XM_044325373.1 0 13 0 0 23 Q2Y8V8 2.23e-111 Protein adenylyltransferase SelO (EC 2.7.7.108) Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849 / C 71) NA GO:0000287; GO:0005524; GO:0016779 40400 XM_044313319.1 22 0 46 11 115 O43603 3.14e-28 Galanin receptor type 2 (GAL2-R) (GALR-2) Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell surface receptor signaling pathway [GO:0007166]; feeding behavior [GO:0007631]; galanin-activated signaling pathway [GO:0090663]; inositol phosphate metabolic process [GO:0043647]; learning or memory [GO:0007611]; muscle contraction [GO:0006936]; negative regulation of adenylate cyclase activity [GO:0007194]; neuron projection development [GO:0031175]; neuropeptide signaling pathway [GO:0007218]; phosphatidylinositol metabolic process [GO:0046488]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of large conductance calcium-activated potassium channel activity [GO:1902608]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0004966; GO:0005886; GO:0005929; GO:0006936; GO:0007166; GO:0007188; GO:0007189; GO:0007194; GO:0007200; GO:0007204; GO:0007218; GO:0007611; GO:0007631; GO:0008528; GO:0016020; GO:0017046; GO:0031175; GO:0042923; GO:0043647; GO:0045944; GO:0046488; GO:0090663; GO:1902608 40401 XR_006396169.1 179 28 91 18 529 NA NA NA NA NA NA 40402 XM_044307065.1 0 21 11 0 0 P0CT39 5.39e-72 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 40403 XM_044313464.1 14 0 13 2 28 NA NA NA NA NA NA 40404 XM_044325586.1 27754 47203 16135 16758 15369 P54985 2.65e-81 Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8) (Cyclophilin) (Cyclosporin A-binding protein) (Rotamase) Blattella germanica (German cockroach) (Blatta germanica) protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413] GO:0000413; GO:0003755; GO:0005737; GO:0006457 40405 XR_006391756.1 44 0 45 0 10 NA NA NA NA NA NA 40406 XM_044315669.1 9 0 0 4 10 NA NA NA NA NA NA 40407 XM_044307784.1 138 46 38 59 1 NA NA NA NA NA NA 40408 XM_029349036.2 72 16 61 569 5 NA NA NA NA NA NA 40409 XM_029336059.2 160 392 11 53 159 NA NA NA NA NA NA 40410 XM_044326409.1 176 40 20 435 2 NA NA NA NA NA NA 40411 XM_044307124.1 12 28 24 3 8 Q9U6Y6 2.63e-102 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 40412 XM_029327146.2 214 71 320 214 217 P43140 1.74e-28 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) Rattus norvegicus (Rat) activation of phospholipase C activity [GO:0007202]; adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; adrenergic receptor signaling pathway [GO:0071875]; adult heart development [GO:0007512]; aging [GO:0007568]; calcium ion transport into cytosol [GO:0060402]; cell growth involved in cardiac muscle cell development [GO:0061049]; cell-cell signaling [GO:0007267]; MAPK cascade [GO:0000165]; micturition [GO:0060073]; multicellular organism aging [GO:0010259]; negative regulation of autophagy [GO:0010507]; negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure [GO:0001985]; negative regulation of Rho protein signal transduction [GO:0035024]; neuron-glial cell signaling [GO:0150099]; norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001994]; organ growth [GO:0035265]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; pilomotor reflex [GO:0097195]; positive regulation of action potential [GO:0045760]; positive regulation of cardiac muscle contraction [GO:0060452]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of heart rate [GO:0010460]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; positive regulation of systemic arterial blood pressure [GO:0003084]; positive regulation of the force of heart contraction by epinephrine-norepinephrine [GO:0001997]; positive regulation of vasoconstriction [GO:0045907]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of blood pressure [GO:0008217]; response to hormone [GO:0009725]; response to xenobiotic stimulus [GO:0009410] GO:0000165; GO:0001985; GO:0001994; GO:0001996; GO:0001997; GO:0003084; GO:0004930; GO:0004937; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0005901; GO:0007200; GO:0007202; GO:0007204; GO:0007267; GO:0007512; GO:0007568; GO:0008217; GO:0009410; GO:0009725; GO:0010259; GO:0010460; GO:0010507; GO:0010613; GO:0016020; GO:0030018; GO:0030315; GO:0031965; GO:0032230; GO:0035024; GO:0035265; GO:0042734; GO:0043410; GO:0045211; GO:0045760; GO:0045907; GO:0045987; GO:0046982; GO:0060073; GO:0060402; GO:0060452; GO:0061049; GO:0070374; GO:0071875; GO:0071880; GO:0090037; GO:0097195; GO:0098691; GO:0098978; GO:0098982; GO:0099171; GO:0150099; GO:1903997 40413 XR_003823473.2 2 4 17 18 12 NA NA NA NA NA NA 40414 XR_006394604.1 134 0 22 81 30 NA NA NA NA NA NA 40415 XM_029326634.2 558 655 313 593 479 Q7KWX9 1.48e-67 Putative exosome complex component rrp40 (Exosome component 3) (Ribosomal RNA-processing protein 40) Dictyostelium discoideum (Social amoeba) CUT catabolic process [GO:0071034]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; U4 snRNA 3'-end processing [GO:0034475] GO:0000176; GO:0000177; GO:0000178; GO:0000467; GO:0003723; GO:0005730; GO:0034427; GO:0034475; GO:0043928; GO:0071034; GO:0071035; GO:0071038; GO:0071051 40416 XM_029340400.2 3465 2526 2130 3973 696 Q9NYT6 2.13e-40 Zinc finger protein 226 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 40417 XM_029340400.2 3465 2526 2130 3973 696 Q9NYT6 4.75e-24 Zinc finger protein 226 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 40418 XM_044329002.1 7 95 19 93 63 Q2LE78 2.21e-76 BTB/POZ domain-containing protein 6 Xenopus laevis (African clawed frog) NA GO:0005737 40419 XM_029329979.2 112 30 94 69 273 Q32LL6 4.35e-42 MORN repeat-containing protein 5 Bos taurus (Bovine) NA NA 40420 XR_006391919.1 33 4 16 27 67 NA NA NA NA NA NA 40421 XM_044323850.1 30 15 35 0 74 NA NA NA NA NA NA 40422 XM_029328759.2 187 130 158 176 235 NA NA NA NA NA NA 40423 XM_044325000.1 0 0 4 6 5 NA NA NA NA NA NA 40424 XM_044315853.1 28 21 109 43 230 NA NA NA NA NA NA 40425 XR_003823651.2 8 2 0 4 36 NA NA NA NA NA NA 40426 XM_044314480.1 0 0 153 0 220 Q9NZJ4 0 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 40427 XM_044314480.1 0 0 153 0 220 Q9NZJ4 2.78e-52 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 40428 XM_044314480.1 0 0 153 0 220 Q9NZJ4 1.06e-42 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 40429 XM_044314480.1 0 0 153 0 220 Q9NZJ4 2.56e-41 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 40430 XM_044318357.1 95 111 45 51 136 A4IFA7 4.83e-61 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) (3-ketoacyl-[acyl-carrier-protein] reductase beta subunit) (KAR beta subunit) (Carbonyl reductase family member 4) (CBR4) (Quinone reductase CBR4) (EC 1.6.5.10) Bos taurus (Bovine) daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fatty acid biosynthetic process [GO:0006633]; protein heterotetramerization [GO:0051290]; protein homotetramerization [GO:0051289] GO:0004316; GO:0005759; GO:0006633; GO:0008753; GO:0016616; GO:0044597; GO:0044598; GO:0048038; GO:0051289; GO:0051290; GO:0070402; GO:1990204 40431 XM_029348920.2 32973 30122 29221 27316 29345 NA NA NA NA NA NA 40432 XM_029329234.2 0 0 21 0 17 Q9U6A0 2.01e-61 Sodium/potassium/calcium exchanger Nckx30C (Na(+)/K(+)/Ca(2+)-exchange protein Nckx30C) Drosophila melanogaster (Fruit fly) calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; compound eye development [GO:0048749]; sodium ion transport [GO:0006814] GO:0005262; GO:0005886; GO:0006814; GO:0006816; GO:0006874; GO:0008273; GO:0015293; GO:0016020; GO:0048749; GO:0070588 40433 XM_044324560.1 45 26 704 1883 359 NA NA NA NA NA NA 40434 XM_044314583.1 54 56 14 87 43 NA NA NA NA NA NA 40435 XM_029338599.2 110 52 74 208 231 NA NA NA NA NA NA 40436 XM_029337195.2 1795 983 896 1026 668 Q15438 3.56e-180 Cytohesin-1 (PH, SEC7 and coiled-coil domain-containing protein 1) (SEC7 homolog B2-1) Homo sapiens (Human) establishment of epithelial cell polarity [GO:0090162]; regulation of ARF protein signal transduction [GO:0032012]; regulation of cell adhesion [GO:0030155]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0005085; GO:0005737; GO:0005829; GO:0005886; GO:0005912; GO:0005923; GO:0008289; GO:0016192; GO:0030155; GO:0031234; GO:0032012; GO:0090162 40437 XM_044327965.1 172 128 114 11 30 NA NA NA NA NA NA 40438 XM_044328460.1 4120 3116 1729 1588 2435 Q7ZV35 8.31e-58 Mediator of RNA polymerase II transcription subunit 7 (Cofactor required for Sp1 transcriptional activation subunit 9) (CRSP complex subunit 9) (Mediator complex subunit 7) Danio rerio (Zebrafish) (Brachydanio rerio) positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; RNA polymerase II preinitiation complex assembly [GO:0051123] GO:0003712; GO:0016592; GO:0032968; GO:0051123; GO:0060261 40439 XM_029352526.2 22 12 94 67 54 Q9P2K3 6.22e-112 REST corepressor 3 Homo sapiens (Human) histone deacetylation [GO:0016575]; negative regulation of DNA-templated transcription [GO:0045892]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000118; GO:0003714; GO:0005654; GO:0005667; GO:0005829; GO:0006357; GO:0016575; GO:0045892 40440 XM_029358170.2 19 0 60 96 195 Q6REY9 2.24e-96 Rho GTPase-activating protein 20 (RA and RhoGAP domain-containing protein) (RARhoGAP) (Rho-type GTPase-activating protein 20) Rattus norvegicus (Rat) regulation of Rho protein signal transduction [GO:0035023]; signal transduction [GO:0007165] GO:0005096; GO:0007165; GO:0031267; GO:0035023 40441 XM_044323079.1 7 0 6 152 210 NA NA NA NA NA NA 40442 XM_029355624.2 1201 736 645 1119 1368 Q91YR7 0 Pre-mRNA-processing factor 6 (PRP6 homolog) (U5 snRNP-associated 102 kDa protein) (U5-102 kDa protein) Mus musculus (Mouse) mRNA splicing, via spliceosome [GO:0000398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; RNA localization [GO:0006403]; spliceosomal tri-snRNP complex assembly [GO:0000244] GO:0000244; GO:0000398; GO:0003713; GO:0003723; GO:0005634; GO:0005682; GO:0006403; GO:0016607; GO:0042802; GO:0043021; GO:0045944; GO:0046540; GO:0050681; GO:0071005; GO:0071013 40443 XM_029352351.2 61 24 0 10 0 NA NA NA NA NA NA 40444 XM_029335356.2 0 0 29 80 37 P30884 1.08e-75 Bone morphogenetic protein 2-B (BMP-2-II) Xenopus laevis (African clawed frog) cartilage development [GO:0051216]; cell differentiation [GO:0030154]; ossification [GO:0001503] GO:0001503; GO:0005125; GO:0005615; GO:0008083; GO:0030154; GO:0051216 40445 XR_006394908.1 26 3 14 6 139 NA NA NA NA NA NA 40446 XM_044323266.1 0 35 0 6 99 NA NA NA NA NA NA 40447 XM_044312434.1 0 7 0 6 0 NA NA NA NA NA NA 40448 XM_029350941.2 208 341 80 283 106 NA NA NA NA NA NA 40449 XM_029326983.2 857 786 696 759 657 NA NA NA NA NA NA 40450 XR_006396156.1 49 23 3 7 20 NA NA NA NA NA NA 40451 XM_029358285.2 833 485 395 646 498 P34528 3.83e-106 Putative serine protease K12H4.7 (EC 3.4.-.-) Caenorhabditis elegans innate immune response [GO:0045087]; proteolysis [GO:0006508] GO:0006508; GO:0008236; GO:0008239; GO:0045087 40452 XM_029356779.2 1828 843 656 1652 1075 Q5ZJ43 5.33e-131 Exocyst complex component 8 Gallus gallus (Chicken) exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; protein localization [GO:0008104]; protein transport [GO:0015031] GO:0000145; GO:0006887; GO:0006893; GO:0008104; GO:0015031; GO:0030426; GO:0048471 40453 XR_006395467.1 483 343 264 1146 612 NA NA NA NA NA NA 40454 XM_044310051.1 5 1 2 0 37 NA NA NA NA NA NA 40455 XR_006392218.1 0 0 22 0 13 NA NA NA NA NA NA 40456 XM_044309168.1 623 170 130 13 280 NA NA NA NA NA NA 40457 XM_029358192.2 22 491 0 0 0 P15311 1.59e-155 Ezrin (Cytovillin) (Villin-2) (p81) Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; astral microtubule organization [GO:0030953]; cellular response to cAMP [GO:0071320]; cortical microtubule organization [GO:0043622]; establishment of centrosome localization [GO:0051660]; establishment of endothelial barrier [GO:0061028]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; filopodium assembly [GO:0046847]; intestinal D-glucose absorption [GO:0001951]; leukocyte cell-cell adhesion [GO:0007159]; membrane to membrane docking [GO:0022614]; microvillus assembly [GO:0030033]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of gene expression [GO:0010628]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein secretion [GO:0050714]; postsynaptic actin cytoskeleton organization [GO:0098974]; protein kinase A signaling [GO:0010737]; protein localization to cell cortex [GO:0072697]; protein localization to plasma membrane [GO:0072659]; protein-containing complex localization [GO:0031503]; receptor internalization [GO:0031623]; regulation of cell shape [GO:0008360]; regulation of microvillus length [GO:0032532]; regulation of organelle assembly [GO:1902115]; sphingosine-1-phosphate receptor signaling pathway [GO:0003376]; terminal web assembly [GO:1902896] GO:0000122; GO:0001650; GO:0001726; GO:0001772; GO:0001931; GO:0001951; GO:0003376; GO:0003723; GO:0003779; GO:0005615; GO:0005737; GO:0005768; GO:0005829; GO:0005884; GO:0005886; GO:0005902; GO:0005903; GO:0005912; GO:0005925; GO:0007159; GO:0008017; GO:0008022; GO:0008360; GO:0010628; GO:0010737; GO:0015629; GO:0016020; GO:0016323; GO:0016324; GO:0019898; GO:0019904; GO:0022614; GO:0030033; GO:0030175; GO:0030863; GO:0030953; GO:0031503; GO:0031528; GO:0031532; GO:0031623; GO:0031982; GO:0032532; GO:0032587; GO:0032703; GO:0032991; GO:0034236; GO:0034237; GO:0035088; GO:0036064; GO:0040018; GO:0042802; GO:0042995; GO:0043622; GO:0044548; GO:0044853; GO:0045177; GO:0045296; GO:0045732; GO:0046847; GO:0048015; GO:0048471; GO:0050714; GO:0050839; GO:0050860; GO:0051015; GO:0051017; GO:0051018; GO:0051117; GO:0051660; GO:0061028; GO:0070062; GO:0070373; GO:0071320; GO:0071944; GO:0072659; GO:0072697; GO:0097718; GO:0098592; GO:0098974; GO:1902115; GO:1902896; GO:1902966; GO:1903078; GO:1903753; GO:2000643 40458 XM_044318978.1 39 99 0 206 20 B5DF45 1.31e-113 TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6) Rattus norvegicus (Rat) activation of NF-kappaB-inducing kinase activity [GO:0007250]; activation of protein kinase activity [GO:0032147]; animal organ morphogenesis [GO:0009887]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; bone remodeling [GO:0046849]; bone resorption [GO:0045453]; cell development [GO:0048468]; cellular response to cytokine stimulus [GO:0071345]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-17-mediated signaling pathway [GO:0097400]; JNK cascade [GO:0007254]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin production [GO:0002637]; response to interleukin-1 [GO:0070555]; response to ischemia [GO:0002931]; signal transduction [GO:0007165]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000122; GO:0000209; GO:0001503; GO:0001701; GO:0001843; GO:0002637; GO:0002726; GO:0002931; GO:0004842; GO:0005164; GO:0005634; GO:0005737; GO:0005811; GO:0005829; GO:0005886; GO:0005938; GO:0006955; GO:0006974; GO:0007165; GO:0007249; GO:0007250; GO:0007254; GO:0008270; GO:0009887; GO:0009898; GO:0016567; GO:0019221; GO:0019886; GO:0019901; GO:0030316; GO:0031435; GO:0031624; GO:0031625; GO:0031666; GO:0031996; GO:0032147; GO:0032735; GO:0032743; GO:0032755; GO:0032813; GO:0032991; GO:0033209; GO:0035631; GO:0042088; GO:0042102; GO:0042475; GO:0042802; GO:0042826; GO:0042981; GO:0043011; GO:0043122; GO:0043123; GO:0043422; GO:0043507; GO:0045453; GO:0045672; GO:0045892; GO:0045944; GO:0046330; GO:0046849; GO:0047485; GO:0048468; GO:0048471; GO:0048661; GO:0050852; GO:0051091; GO:0051092; GO:0051865; GO:0061630; GO:0070498; GO:0070534; GO:0070555; GO:0071222; GO:0071345; GO:0097400; GO:1901224; GO:1904996; GO:2000679 40459 XM_029346251.2 54 15 88 74 68 A7S4N4 5.51e-105 Probable serine incorporator Nematostella vectensis (Starlet sea anemone) phospholipid biosynthetic process [GO:0008654] GO:0005789; GO:0008654; GO:0016020 40460 XR_006392229.1 0 17 0 26 23 NA NA NA NA NA NA 40461 XM_044322170.1 323 221 322 513 497 O95672 2.24e-111 Endothelin-converting enzyme-like 1 (EC 3.4.24.-) (Xce protein) Homo sapiens (Human) neuropeptide signaling pathway [GO:0007218]; protein processing [GO:0016485]; respiratory system process [GO:0003016] GO:0003016; GO:0004222; GO:0005886; GO:0007218; GO:0008237; GO:0016485; GO:0046872 40462 XR_003826121.2 17 12 10 3 0 NA NA NA NA NA NA 40463 XM_044326572.1 597 187 668 929 39 NA NA NA NA NA NA 40464 XM_029357557.2 0 0 0 9 0 Q91YE6 0 Importin-9 (Imp9) (Importin-9a) (Imp9a) (Importin-9b) (Imp9b) (Ran-binding protein 9) (RanBP9) Mus musculus (Mouse) proteasome localization [GO:0031144]; protein import into nucleus [GO:0006606]; protein stabilization [GO:0050821]; ribosome biogenesis [GO:0042254] GO:0005635; GO:0005737; GO:0005829; GO:0006606; GO:0031144; GO:0031267; GO:0042254; GO:0042393; GO:0050821; GO:0061608; GO:0140713 40465 XR_003828244.2 30 9 32 42 14 NA NA NA NA NA NA 40466 XM_029352735.2 1 1 43 13 59 NA NA NA NA NA NA 40467 XR_006394727.1 1222 80 461 0 907 Q6IQX7 1.43e-106 Chondroitin sulfate synthase 2 (EC 2.4.1.175) (EC 2.4.1.226) (Chondroitin glucuronyltransferase 2) (Chondroitin-polymerizing factor) (ChPF) (Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II) (N-acetylgalactosaminyltransferase 2) Mus musculus (Mouse) chondroitin sulfate biosynthetic process [GO:0030206] GO:0005759; GO:0005794; GO:0005829; GO:0008376; GO:0016757; GO:0030206; GO:0032580; GO:0046872; GO:0047238; GO:0050510 40468 XM_029339170.2 428 0 163 233 450 Q5VTY9 1.98e-54 Protein-cysteine N-palmitoyltransferase HHAT (EC 2.3.1.-) (Hedgehog acyltransferase) (Melanoma antigen recognized by T-cells 2) (MART-2) (Skinny hedgehog protein 1) Homo sapiens (Human) N-terminal peptidyl-L-cysteine N-palmitoylation [GO:0018009]; protein palmitoylation [GO:0018345]; smoothened signaling pathway [GO:0007224] GO:0000139; GO:0005525; GO:0005783; GO:0005789; GO:0005794; GO:0007224; GO:0008374; GO:0016409; GO:0016746; GO:0018009; GO:0018345 40469 XM_044318054.1 22 2 25 3 104 Q92752 1.88e-64 Tenascin-R (TN-R) (Janusin) (Restrictin) Homo sapiens (Human) associative learning [GO:0008306]; axon extension involved in regeneration [GO:0048677]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198]; locomotory exploration behavior [GO:0035641]; long-term synaptic potentiation [GO:0060291]; negative regulation of axon extension involved in regeneration [GO:0048692]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of neuron projection development [GO:0010977]; negative regulation of synaptic transmission [GO:0050805]; neuroblast migration [GO:0097402]; neuromuscular process controlling balance [GO:0050885]; neuron cell-cell adhesion [GO:0007158]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transmission of nerve impulse [GO:0051971]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of cell migration [GO:0030334]; synapse organization [GO:0050808]; synaptic transmission, glutamatergic [GO:0035249]; telencephalon cell migration [GO:0022029] GO:0005102; GO:0005576; GO:0005615; GO:0007155; GO:0007158; GO:0007411; GO:0008306; GO:0009986; GO:0010977; GO:0022029; GO:0022408; GO:0030155; GO:0030198; GO:0030334; GO:0035249; GO:0035641; GO:0045121; GO:0045595; GO:0048677; GO:0048692; GO:0050805; GO:0050808; GO:0050885; GO:0051968; GO:0051971; GO:0060291; GO:0062023; GO:0072534; GO:0090733; GO:0097402; GO:0098685; GO:0098978 40470 XM_044309780.1 20 5 3 17 37 NA NA NA NA NA NA 40471 XM_044315266.1 0 0 10 3 0 NA NA NA NA NA NA 40472 XM_044313297.1 126 21 0 42 42 F1NWE3 3.58e-141 Receptor-type tyrosine-protein phosphatase S (R-PTP-S) (EC 3.1.3.48) (Chick receptor tyrosine phosphatase alpha) (CRYP alpha) (CRYPalpha) Gallus gallus (Chicken) negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; synaptic membrane adhesion [GO:0099560] GO:0004725; GO:0005886; GO:0006470; GO:0008201; GO:0030424; GO:0030426; GO:0030517; GO:0030672; GO:0035335; GO:0042803; GO:0043204; GO:0043395; GO:0048671; GO:0048681; GO:0061000; GO:0098839; GO:0099560 40473 XM_044318143.1 40 6 2 73 13 Q95029 7.32e-92 Cathepsin L (EC 3.4.22.15) (Cysteine proteinase 1) [Cleaved into: Cathepsin L heavy chain; Cathepsin L light chain] Drosophila melanogaster (Fruit fly) digestion [GO:0007586]; immune response [GO:0006955]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603] GO:0004197; GO:0005615; GO:0005764; GO:0006508; GO:0006955; GO:0007586; GO:0008233; GO:0008234; GO:0045169; GO:0051603 40474 XM_044310862.1 51 118 57 154 48 NA NA NA NA NA NA 40475 XR_006395183.1 0 26 0 29 0 NA NA NA NA NA NA 40476 XR_006393365.1 0 0 16 0 0 NA NA NA NA NA NA 40477 XM_029332578.2 127 204 94 106 62 NA NA NA NA NA NA 40478 XM_044324536.1 24 1 40 3 220 NA NA NA NA NA NA 40479 XM_044308659.1 3 18 21 9 21 NA NA NA NA NA NA 40480 XM_029326406.2 77 52 102 77 73 NA NA NA NA NA NA 40481 XM_044309436.1 349 342 220 245 188 NA NA NA NA NA NA 40482 XM_029343596.2 57 62 40 69 170 Q60847 2.36e-21 Collagen alpha-1(XII) chain Mus musculus (Mouse) cell adhesion [GO:0007155]; endodermal cell differentiation [GO:0035987] GO:0005595; GO:0005615; GO:0007155; GO:0035987; GO:0062023 40483 XM_029336821.2 0 0 0 0 230 Q5VVW2 0 GTPase-activating Rap/Ran-GAP domain-like protein 3 Homo sapiens (Human) activation of GTPase activity [GO:0090630]; regulation of small GTPase mediated signal transduction [GO:0051056] GO:0005096; GO:0005737; GO:0051056; GO:0090630 40484 XM_044311361.1 168 96 91 148 84 C3VPR6 2.69e-26 Protein NLRC5 Mus musculus (Mouse) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of type II interferon-mediated signaling pathway [GO:0060335]; regulation of kinase activity [GO:0043549]; response to bacterium [GO:0009617] GO:0000978; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0009617; GO:0032088; GO:0035556; GO:0043549; GO:0045087; GO:0045345; GO:0045944; GO:0051607; GO:0060335; GO:0060339; GO:0060340 40485 XR_006394664.1 5 4 1 3 6 NA NA NA NA NA NA 40486 XM_044313906.1 101 8 59 33 673 NA NA NA NA NA NA 40487 XM_029343332.2 5375 3443 2098 5396 6722 Q0IHW8 0 Clustered mitochondria protein homolog Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) intracellular distribution of mitochondria [GO:0048312]; mitochondrion organization [GO:0007005] GO:0003729; GO:0005737; GO:0007005; GO:0048312 40488 XM_044307241.1 218 330 156 207 238 Q8D3M4 4.52e-106 2-aminoethylphosphonate--pyruvate transaminase (EC 2.6.1.37) (2-aminoethylphosphonate aminotransferase) (AEP transaminase) (AEPT) Vibrio vulnificus (strain CMCP6) organic phosphonate catabolic process [GO:0019700] GO:0019700; GO:0047304 40489 XM_044316053.1 1 0 3 0 26 NA NA NA NA NA NA 40490 XM_029356902.2 2663 2787 843 1799 1442 Q3U7U3 4.32e-54 F-box only protein 7 Mus musculus (Mouse) autophagy of mitochondrion [GO:0000422]; lymphocyte differentiation [GO:0030098]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of lymphocyte differentiation [GO:0045620]; negative regulation of neuron death [GO:1901215]; negative regulation of oxidative stress-induced neuron death [GO:1903204]; positive regulation of autophagy of mitochondrion [GO:1903599]; protein targeting to mitochondrion [GO:0006626]; protein ubiquitination [GO:0016567]; regulation of locomotion [GO:0040012]; regulation of neuron projection development [GO:0010975]; regulation of protein stability [GO:0031647]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000151; GO:0000422; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005829; GO:0006511; GO:0006626; GO:0010975; GO:0016567; GO:0019005; GO:0019901; GO:0030098; GO:0031625; GO:0031647; GO:0032991; GO:0040012; GO:0043130; GO:0045620; GO:0045736; GO:0046982; GO:0097409; GO:0097414; GO:0097462; GO:1901215; GO:1903204; GO:1903208; GO:1903599; GO:1990037; GO:1990038; GO:1990756; GO:2000134 40491 XM_029348636.2 3560 3045 2282 3506 2900 Q5ZLL1 0 Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1) Gallus gallus (Chicken) endocytosis [GO:0006897]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein phosphorylation [GO:0006468]; rhythmic process [GO:0048511]; signal transduction [GO:0007165] GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0006468; GO:0006897; GO:0007165; GO:0018105; GO:0032436; GO:0048511; GO:0090263; GO:0106310 40492 XR_006392066.1 27 19 0 11 4 NA NA NA NA NA NA 40493 XM_044328630.1 335 123 89 123 423 P54145 1.11e-84 Putative ammonium transporter 1 Caenorhabditis elegans ammonium homeostasis [GO:0097272]; ammonium transmembrane transport [GO:0072488] GO:0005886; GO:0008519; GO:0072488; GO:0097272 40494 XM_044313466.1 573 348 164 1010 725 NA NA NA NA NA NA 40495 XR_006397363.1 0 0 20 0 0 NA NA NA NA NA NA 40496 XM_044313710.1 13 25 4 8 50 NA NA NA NA NA NA 40497 XM_044314458.1 0 0 0 16 0 NA NA NA NA NA NA 40498 XM_029351702.2 443 462 281 596 201 Q9H089 0 Large subunit GTPase 1 homolog (hLsg1) (EC 3.6.1.-) Homo sapiens (Human) nuclear export [GO:0051168]; protein transport [GO:0015031]; ribosomal subunit export from nucleus [GO:0000054] GO:0000054; GO:0003924; GO:0005525; GO:0005654; GO:0005783; GO:0005829; GO:0015030; GO:0015031; GO:0016020; GO:0016604; GO:0051168 40499 XR_006397716.1 76 66 69 102 75 NA NA NA NA NA NA 40500 XM_044328163.1 0 0 0 0 22 NA NA NA NA NA NA 40501 XM_044310998.1 0 0 61 12 0 NA NA NA NA NA NA 40502 XM_029358330.2 203 147 111 219 204 Q6DJ06 1.92e-54 LIM domain transcription factor LMO4.2 (LIM domain only protein 4.2) (LMO-4.2) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell differentiation [GO:0030154]; gastrulation [GO:0007369]; mesoderm development [GO:0007498]; negative regulation of neuron differentiation [GO:0045665]; nervous system development [GO:0007399]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0003712; GO:0007369; GO:0007399; GO:0007498; GO:0030154; GO:0045665; GO:0045944; GO:0046872 40503 XM_029354923.2 238 273 247 152 94 NA NA NA NA NA NA 40504 XM_029357041.2 17013 13991 8003 6736 8258 P52209 0 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44) Homo sapiens (Human) D-gluconate catabolic process [GO:0046177]; pentose biosynthetic process [GO:0019322]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, oxidative branch [GO:0009051] GO:0004616; GO:0005634; GO:0005829; GO:0006098; GO:0009051; GO:0019322; GO:0046177; GO:0050661; GO:0070062 40505 XM_029357576.2 1524 1621 1067 1406 1682 NA NA NA NA NA NA 40506 XM_044313248.1 1951 1193 916 1417 1531 Q95J56 6.34e-41 DnaJ homolog subfamily C member 14 (J domain protein interacting with viral protein) (Jiv) Bos taurus (Bovine) protein transport [GO:0015031] GO:0005789; GO:0015031; GO:0050780 40507 XR_003824780.2 730 898 466 519 717 NA NA NA NA NA NA 40508 XM_044311879.1 7 15 14 8 0 NA NA NA NA NA NA 40509 XM_044319139.1 96 118 66 191 144 NA NA NA NA NA NA 40510 XM_044308241.1 176 76 70 120 200 NA NA NA NA NA NA 40511 XR_003827310.2 22 5 2 25 5 NA NA NA NA NA NA 40512 XM_029328515.2 1061 1010 732 938 603 Q8BT60 0 Copine-3 (Copine III) Mus musculus (Mouse) cellular response to calcium ion [GO:0071277]; cellular response to growth factor stimulus [GO:0071363]; ERBB2 signaling pathway [GO:0038128]; positive regulation of cell migration [GO:0030335] GO:0004674; GO:0005544; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005739; GO:0005829; GO:0005886; GO:0005925; GO:0030054; GO:0030335; GO:0030971; GO:0038128; GO:0046872; GO:0048306; GO:0071277; GO:0071363 40513 XM_044319290.1 2129 1579 1113 2256 2479 Q28165 7.02e-58 Polyadenylate-binding protein 2 (PABP-2) (Poly(A)-binding protein 2) (Nuclear poly(A)-binding protein 1) (Poly(A)-binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1) Bos taurus (Bovine) cellular response to lipopolysaccharide [GO:0071222]; MAPK cascade [GO:0000165]; mRNA processing [GO:0006397]; positive regulation of polynucleotide adenylyltransferase activity [GO:1904247] GO:0000165; GO:0003723; GO:0005634; GO:0005737; GO:0006397; GO:0016607; GO:0042405; GO:0043621; GO:0070063; GO:0071222; GO:1904247; GO:1990904 40514 XM_029339325.2 0 11 102 45 63 NA NA NA NA NA NA 40515 XR_006395646.1 14 24 57 7 65 NA NA NA NA NA NA 40516 XM_029357974.2 51 27 1 11 9 NA NA NA NA NA NA 40517 XR_003826783.2 29 10 12 31 29 NA NA NA NA NA NA 40518 XM_044319222.1 596 874 378 368 418 Q503Z8 4.48e-44 NA NA NA NA 40519 XM_029350987.2 100 70 72 37 65 Q9NPC2 6.86e-28 Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3) (Two pore potassium channel KT3.2) (Two pore K(+) channel KT3.2) Homo sapiens (Human) potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; stabilization of membrane potential [GO:0030322] GO:0005267; GO:0005886; GO:0006813; GO:0008021; GO:0015271; GO:0022841; GO:0030322; GO:0071805; GO:1990573 40520 XM_029329581.2 406 333 403 808 681 Q9Y6N7 2.84e-23 Roundabout homolog 1 (Deleted in U twenty twenty) (H-Robo-1) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; axon midline choice point recognition [GO:0016199]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; endocardial cushion formation [GO:0003272]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of gene expression [GO:0010629]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; negative regulation of negative chemotaxis [GO:0050925]; nervous system development [GO:0007399]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; pulmonary valve morphogenesis [GO:0003184]; Roundabout signaling pathway [GO:0035385]; ventricular septum morphogenesis [GO:0060412] GO:0002042; GO:0003148; GO:0003180; GO:0003184; GO:0003272; GO:0005737; GO:0005886; GO:0006919; GO:0007155; GO:0007156; GO:0007399; GO:0008046; GO:0009986; GO:0010628; GO:0010629; GO:0016199; GO:0021836; GO:0030275; GO:0030336; GO:0030424; GO:0033116; GO:0033600; GO:0035025; GO:0035385; GO:0035481; GO:0035904; GO:0042802; GO:0043406; GO:0050772; GO:0050925; GO:0060412; GO:0070100; GO:1900748 40521 XM_029329074.2 534 410 511 386 351 Q5F448 0 Golgi pH regulator (Protein GPR89) Gallus gallus (Chicken) intracellular pH reduction [GO:0051452]; protein transport [GO:0015031]; regulation of ion transmembrane transport [GO:0034765]; skin development [GO:0043588]; T cell differentiation [GO:0030217] GO:0000139; GO:0008308; GO:0015031; GO:0030217; GO:0030660; GO:0032580; GO:0034765; GO:0043588; GO:0051452 40522 XR_006395069.1 285 222 329 209 705 NA NA NA NA NA NA 40523 XM_044307100.1 0 5 20 5 10 NA NA NA NA NA NA 40524 XM_029344873.2 127 13 130 26 433 O57422 3.55e-33 Melanopsin-B (Opsin-4B) (xMOP) Xenopus laevis (African clawed frog) phototransduction [GO:0007602]; visual perception [GO:0007601] GO:0004930; GO:0005886; GO:0007601; GO:0007602; GO:0009881 40525 XM_044319426.1 17 339 908 41 144 NA NA NA NA NA NA 40526 XM_029356077.2 1713 2050 147 381 1593 NA NA NA NA NA NA 40527 XM_044327353.1 10 19 74 9 52 NA NA NA NA NA NA 40528 XM_044317191.1 150 103 167 248 25 F2Z5G5 8.22e-97 Alpha-centractin (Centractin) (ARP1) Sus scrofa (Pig) NA NA 40529 XM_044311957.1 0 0 0 0 10 NA NA NA NA NA NA 40530 XM_029330309.2 344 83 67 91 227 Q62384 3.56e-164 Zinc finger protein ZPR1 (Zinc finger protein 259) Mus musculus (Mouse) apoptotic process involved in development [GO:1902742]; axon development [GO:0061564]; Cajal body organization [GO:0030576]; cell population proliferation [GO:0008283]; cellular response to epidermal growth factor stimulus [GO:0071364]; DNA endoreduplication [GO:0042023]; inner cell mass cell proliferation [GO:0001833]; microtubule cytoskeleton organization [GO:0000226]; mRNA processing [GO:0006397]; negative regulation of motor neuron apoptotic process [GO:2000672]; positive regulation of cell cycle [GO:0045787]; positive regulation of gene expression [GO:0010628]; positive regulation of growth [GO:0045927]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of RNA splicing [GO:0033120]; positive regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0071931]; pre-mRNA catabolic process [GO:1990261]; regulation of myelination [GO:0031641]; RNA splicing [GO:0008380]; spinal cord development [GO:0021510]; trophectodermal cell proliferation [GO:0001834] GO:0000226; GO:0001833; GO:0001834; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0006397; GO:0008270; GO:0008283; GO:0008380; GO:0010628; GO:0015030; GO:0021510; GO:0030424; GO:0030426; GO:0030576; GO:0030971; GO:0031369; GO:0031641; GO:0033120; GO:0042023; GO:0042307; GO:0043025; GO:0043204; GO:0045787; GO:0045927; GO:0048471; GO:0061564; GO:0071364; GO:0071931; GO:0097504; GO:1902742; GO:1990261; GO:2000672 40531 XM_044307450.1 2672 25 29 45 6 NA NA NA NA NA NA 40532 XM_044322257.1 0 0 163 0 0 NA NA NA NA NA NA 40533 XM_029323637.2 403 208 208 484 492 Q96J01 4.46e-179 THO complex subunit 3 (Tho3) (TEX1 homolog) (hTREX45) Homo sapiens (Human) mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; RNA splicing [GO:0008380]; viral mRNA export from host cell nucleus [GO:0046784] GO:0000346; GO:0000445; GO:0003723; GO:0005654; GO:0006397; GO:0006406; GO:0008380; GO:0016607; GO:0046784 40534 XM_044317408.1 754 186 257 69 1149 NA NA NA NA NA NA 40535 XM_044327721.1 57 0 0 11 33 NA NA NA NA NA NA 40536 XR_003824306.2 108 49 10 61 66 NA NA NA NA NA NA 40537 XM_044315582.1 13 0 4 20 30 NA NA NA NA NA NA 40538 XR_006397186.1 44 71 25 66 150 NA NA NA NA NA NA 40539 XM_029347062.2 0 0 0 128 207 F1N476 1.23e-140 Endothelin-converting enzyme 2 (ECE-2) (EC 3.4.24.71) Bos taurus (Bovine) brain development [GO:0007420]; cardioblast differentiation [GO:0010002]; heart development [GO:0007507]; peptide hormone processing [GO:0016486] GO:0000139; GO:0004222; GO:0007420; GO:0007507; GO:0010002; GO:0016486; GO:0030658; GO:0030659; GO:0046872 40540 XR_006395124.1 4 4 9 10 19 NA NA NA NA NA NA 40541 XM_044317279.1 0 0 6 0 0 NA NA NA NA NA NA 40542 XR_006396987.1 0 0 0 18 0 NA NA NA NA NA NA 40543 XM_044313381.1 13 1 0 4 30 NA NA NA NA NA NA 40544 XM_044311823.1 1 5 27 38 35 B8VIU6 6.66e-42 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 40545 XM_029352071.2 221 864 469 423 0 Q9Y6R4 3.52e-36 Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAP three kinase 1) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4) Homo sapiens (Human) chorionic trophoblast cell differentiation [GO:0060718]; intracellular signal transduction [GO:0035556]; male germ-line sex determination [GO:0019100]; MAPK cascade [GO:0000165]; placenta development [GO:0001890]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein phosphorylation [GO:0006468]; regulation of gene expression [GO:0010468]; response to UV-C [GO:0010225] GO:0000165; GO:0001890; GO:0004709; GO:0005524; GO:0005737; GO:0006468; GO:0010225; GO:0010468; GO:0019100; GO:0032212; GO:0035556; GO:0043507; GO:0046872; GO:0048471; GO:0051973; GO:0060718; GO:0106310; GO:1900745; GO:1904355 40546 XM_044308466.1 1060 834 586 985 1357 Q2IA00 3.8e-167 Sperm flagellar protein 2 (Protein KPL2) Sus scrofa (Pig) sperm axoneme assembly [GO:0007288] GO:0002177; GO:0005794; GO:0007288; GO:0036126; GO:0097225 40547 XM_044308466.1 1060 834 586 985 1357 Q2IA00 8.32e-62 Sperm flagellar protein 2 (Protein KPL2) Sus scrofa (Pig) sperm axoneme assembly [GO:0007288] GO:0002177; GO:0005794; GO:0007288; GO:0036126; GO:0097225 40548 XM_044308466.1 1060 834 586 985 1357 Q2IA00 3.04e-50 Sperm flagellar protein 2 (Protein KPL2) Sus scrofa (Pig) sperm axoneme assembly [GO:0007288] GO:0002177; GO:0005794; GO:0007288; GO:0036126; GO:0097225 40549 XM_044307835.1 1319 416 462 2046 1039 Q5UPS7 4.4e-24 Collagen-like protein 4 Acanthamoeba polyphaga mimivirus (APMV) NA GO:0044423 40550 XM_044320705.1 0 9 0 1 1 NA NA NA NA NA NA 40551 XM_044311168.1 0 0 0 9 12 Q9CUX1 5.92e-84 52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (THAP domain-containing protein 0) (THAP domain-containing protein 12) Mus musculus (Mouse) NA GO:0003677; GO:0005634; GO:0046872; GO:0046983 40552 XM_044322279.1 48 2 0 11 24 NA NA NA NA NA NA 40553 XM_029326744.2 2 0 14 1 18 NA NA NA NA NA NA 40554 XR_006393725.1 1 4 4 15 0 NA NA NA NA NA NA 40555 XM_044310210.1 0 0 0 0 8 NA NA NA NA NA NA 40556 XR_006391622.1 3 0 0 0 76 NA NA NA NA NA NA 40557 XM_029342472.2 1519 1603 864 966 674 Q28FC1 4.37e-81 Ubiquitin-conjugating enzyme E2 W (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme W) (N-terminal E2 ubiquitin-conjugating enzyme) (EC 2.3.2.25) (Ubiquitin carrier protein W) (Ubiquitin-protein ligase W) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cellular response to misfolded protein [GO:0071218]; DNA repair [GO:0006281]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein monoubiquitination [GO:0006513]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515] GO:0004842; GO:0005524; GO:0005634; GO:0006281; GO:0006513; GO:0006515; GO:0043161; GO:0061631; GO:0071218 40558 XM_044310076.1 75 68 29 86 30 P10079 1.01e-82 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 40559 XM_044310076.1 75 68 29 86 30 P10079 3.32e-82 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 40560 XM_044310076.1 75 68 29 86 30 P10079 9.21e-82 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 40561 XM_044310076.1 75 68 29 86 30 P10079 1.63e-79 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 40562 XM_044310076.1 75 68 29 86 30 P10079 4.66e-78 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 40563 XM_044310076.1 75 68 29 86 30 P10079 5.24e-77 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 40564 XM_044310076.1 75 68 29 86 30 P10079 3.59e-60 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 40565 XM_044310076.1 75 68 29 86 30 P10079 5.19e-51 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 40566 XM_044310076.1 75 68 29 86 30 P10079 6.73e-49 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 40567 XM_044310076.1 75 68 29 86 30 P10079 1.33e-48 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 40568 XM_044310076.1 75 68 29 86 30 P10079 7.81e-48 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 40569 XM_029345769.2 61 128 1058 1838 691 Q9UHD2 8.61e-144 Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1) Homo sapiens (Human) activation of innate immune response [GO:0002218]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; dendritic cell proliferation [GO:0044565]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of gene expression [GO:0010629]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of macroautophagy [GO:0016239]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of xenophagy [GO:1904417]; protein phosphorylation [GO:0006468]; regulation of neuron death [GO:1901214]; regulation of type I interferon production [GO:0032479]; response to virus [GO:0009615]; type I interferon-mediated signaling pathway [GO:0060337] GO:0002218; GO:0003676; GO:0004672; GO:0004674; GO:0005524; GO:0005654; GO:0005737; GO:0005829; GO:0006468; GO:0006954; GO:0007249; GO:0009615; GO:0010629; GO:0016239; GO:0018105; GO:0018107; GO:0019903; GO:0032479; GO:0032481; GO:0032727; GO:0032728; GO:0033138; GO:0042802; GO:0043123; GO:0043231; GO:0044565; GO:0045087; GO:0045944; GO:0050830; GO:0051219; GO:0051607; GO:0060337; GO:0060340; GO:0106310; GO:1901214; GO:1902554; GO:1904417 40570 XM_044320505.1 705 534 437 1077 1332 Q9Y2U8 1.15e-74 Inner nuclear membrane protein Man1 (LEM domain-containing protein 3) Homo sapiens (Human) negative regulation of activin receptor signaling pathway [GO:0032926]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear envelope organization [GO:0006998] GO:0005637; GO:0006998; GO:0016020; GO:0030512; GO:0030514; GO:0031490; GO:0031965; GO:0032926 40571 XM_044320013.1 38 0 0 0 0 Q9VBW3 2.31e-57 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 40572 XM_029355785.2 54 6 4 3 3 NA NA NA NA NA NA 40573 XM_044327461.1 113 45 93 78 73 F1SS88 1.04e-164 Cilia- and flagella-associated protein 52 (WD repeat-containing protein 16) Sus scrofa (Pig) cilium assembly [GO:0060271]; establishment of left/right asymmetry [GO:0061966]; flagellated sperm motility [GO:0030317] GO:0005879; GO:0005930; GO:0030317; GO:0060271; GO:0061966; GO:0097729 40574 XM_044325047.1 53 12 21 12 59 NA NA NA NA NA NA 40575 XR_006395991.1 6 3 35 623 16 NA NA NA NA NA NA 40576 XM_029330470.2 197 124 103 185 91 Q9D0R2 0 Threonine--tRNA ligase 1, cytoplasmic (EC 6.1.1.3) (Threonine--tRNA ligase, cytoplasmic) (Threonyl-tRNA synthetase) (ThrRS) (Threonyl-tRNA synthetase 1) Mus musculus (Mouse) threonyl-tRNA aminoacylation [GO:0006435] GO:0004829; GO:0005524; GO:0005737; GO:0006435; GO:0008270; GO:0042802 40577 XM_029335681.2 1220 903 1111 1414 1220 P20735 1.17e-131 Glutathione hydrolase 1 proenzyme (EC 3.4.19.13) (Gamma-glutamyltransferase 1) (Gamma-glutamyltranspeptidase 1) (GGT 1) (EC 2.3.2.2) (Leukotriene-C4 hydrolase) (EC 3.4.19.14) (CD antigen CD224) [Cleaved into: Glutathione hydrolase 1 heavy chain; Glutathione hydrolase 1 light chain] Sus scrofa (Pig) glutamate metabolic process [GO:0006536]; glutathione biosynthetic process [GO:0006750]; glutathione catabolic process [GO:0006751]; zymogen activation [GO:0031638] GO:0002951; GO:0005886; GO:0006536; GO:0006750; GO:0006751; GO:0031638; GO:0036374; GO:0102953; GO:0103068 40578 XM_044310734.1 8 2 0 1 46 Q9Y6N7 4.89e-21 Roundabout homolog 1 (Deleted in U twenty twenty) (H-Robo-1) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; axon midline choice point recognition [GO:0016199]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; endocardial cushion formation [GO:0003272]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of gene expression [GO:0010629]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; negative regulation of negative chemotaxis [GO:0050925]; nervous system development [GO:0007399]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; pulmonary valve morphogenesis [GO:0003184]; Roundabout signaling pathway [GO:0035385]; ventricular septum morphogenesis [GO:0060412] GO:0002042; GO:0003148; GO:0003180; GO:0003184; GO:0003272; GO:0005737; GO:0005886; GO:0006919; GO:0007155; GO:0007156; GO:0007399; GO:0008046; GO:0009986; GO:0010628; GO:0010629; GO:0016199; GO:0021836; GO:0030275; GO:0030336; GO:0030424; GO:0033116; GO:0033600; GO:0035025; GO:0035385; GO:0035481; GO:0035904; GO:0042802; GO:0043406; GO:0050772; GO:0050925; GO:0060412; GO:0070100; GO:1900748 40579 XM_029329921.2 13 10 11 8 20 NA NA NA NA NA NA 40580 XM_044317139.1 0 0 0 70 28 NA NA NA NA NA NA 40581 XM_029338597.2 5 6 68 13 11 NA NA NA NA NA NA 40582 XR_006393835.1 4 1 0 9 18 NA NA NA NA NA NA 40583 XM_029336152.2 0 1 7 0 12 NA NA NA NA NA NA 40584 XM_044311409.1 0 0 0 8 20 NA NA NA NA NA NA 40585 XM_044316145.1 0 0 0 0 42 NA NA NA NA NA NA 40586 XM_029331519.2 4 239 0 0 802 Q13627 0 Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.11.23) (EC 2.7.12.1) (Dual specificity YAK1-related kinase) (HP86) (Protein kinase minibrain homolog) (MNBH) (hMNB) Homo sapiens (Human) amyloid-beta formation [GO:0034205]; circadian rhythm [GO:0007623]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of DNA methylation-dependent heterochromatin formation [GO:0090310]; negative regulation of microtubule polymerization [GO:0031115]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; nervous system development [GO:0007399]; peptidyl-serine autophosphorylation [GO:0036289]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of protein deacetylation [GO:0090312]; positive regulation of RNA splicing [GO:0033120]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468] GO:0003713; GO:0003779; GO:0004672; GO:0004674; GO:0004712; GO:0004713; GO:0004715; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005856; GO:0006468; GO:0007399; GO:0007623; GO:0008092; GO:0008353; GO:0015631; GO:0016607; GO:0018105; GO:0018107; GO:0018108; GO:0030424; GO:0030425; GO:0031115; GO:0033120; GO:0034205; GO:0036289; GO:0038083; GO:0042802; GO:0043518; GO:0043621; GO:0045893; GO:0046777; GO:0048025; GO:0048156; GO:0050321; GO:0090310; GO:0090312; GO:0106310; GO:0140857; GO:1990904 40587 XM_044322528.1 137 63 74 119 42 P13944 3.51e-21 Collagen alpha-1(XII) chain (Fibrochimerin) Gallus gallus (Chicken) cell adhesion [GO:0007155]; endodermal cell differentiation [GO:0035987] GO:0005581; GO:0005615; GO:0007155; GO:0035987; GO:0062023 40588 XM_044313301.1 5 0 0 9 0 NA NA NA NA NA NA 40589 XM_044323744.1 0 0 11 0 0 NA NA NA NA NA NA 40590 XM_044320718.1 25 18 45 47 78 NA NA NA NA NA NA 40591 XM_044310251.1 71 21 13 28 31 P04323 6.9e-47 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 40592 XM_029357204.2 220 240 103 486 493 Q9H324 2.11e-110 A disintegrin and metalloproteinase with thrombospondin motifs 10 (ADAM-TS 10) (ADAM-TS10) (ADAMTS-10) (EC 3.4.24.-) Homo sapiens (Human) extracellular matrix organization [GO:0030198]; proteolysis [GO:0006508] GO:0001527; GO:0004222; GO:0005576; GO:0006508; GO:0030198; GO:0031012; GO:0046872; GO:0062023 40593 XM_044328108.1 2820 2011 1341 2514 2022 NA NA NA NA NA NA 40594 XM_029338395.2 28 0 0 17 10 Q96P65 1.05e-25 Pyroglutamylated RF-amide peptide receptor (AQ27) (G-protein coupled receptor 103) (Orexigenic neuropeptide QRFP receptor) (SP9155) Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:0016020 40595 XM_029336792.2 230 14 23 273 65 Q8VHQ9 2.22e-111 Acyl-coenzyme A thioesterase 11 (Acyl-CoA thioesterase 11) (EC 3.1.2.-) (Acyl-CoA thioester hydrolase 11) (Adipose-associated thioesterase) (Brown fat-inducible thioesterase) (BFIT) (Palmitoyl-coenzyme A thioesterase) (EC 3.1.2.2) Mus musculus (Mouse) acyl-CoA metabolic process [GO:0006637]; fatty acid metabolic process [GO:0006631]; intracellular signal transduction [GO:0035556]; negative regulation of cold-induced thermogenesis [GO:0120163]; response to cold [GO:0009409]; response to temperature stimulus [GO:0009266] GO:0005737; GO:0005759; GO:0005829; GO:0006631; GO:0006637; GO:0009266; GO:0009409; GO:0016290; GO:0035556; GO:0036042; GO:0047617; GO:0052816; GO:0102991; GO:0120163 40596 XM_044324440.1 187 145 64 197 247 Q01433 4.53e-29 AMP deaminase 2 (EC 3.5.4.6) (AMP deaminase isoform L) Homo sapiens (Human) AMP metabolic process [GO:0046033]; cyclic purine nucleotide metabolic process [GO:0052652]; energy homeostasis [GO:0097009]; IMP biosynthetic process [GO:0006188]; IMP salvage [GO:0032264] GO:0003876; GO:0005829; GO:0006188; GO:0032264; GO:0042802; GO:0046033; GO:0046872; GO:0052652; GO:0097009 40597 XM_029333110.2 7517 9029 5563 4646 3435 Q9H0N5 1.72e-47 Pterin-4-alpha-carbinolamine dehydratase 2 (PHS 2) (EC 4.2.1.96) (4-alpha-hydroxy-tetrahydropterin dehydratase 2) (DcoH-like protein DCoHm) (Dimerization cofactor of hepatocyte nuclear factor 1 from muscle) (HNF-1-alpha dimerization cofactor) Homo sapiens (Human) positive regulation of DNA-templated transcription [GO:0045893]; tetrahydrobiopterin biosynthetic process [GO:0006729] GO:0004505; GO:0005634; GO:0006729; GO:0008124; GO:0042802; GO:0045893 40598 XM_029348330.2 7 17 25 83 89 NA NA NA NA NA NA 40599 XM_029354061.2 0 16 4 58 1 P30834 7.47e-45 Cytolysin tenebrosin-B (DELTA-actitoxin) Actinia tenebrosa (Australian red waratah sea anemone) cation transport [GO:0006812]; cytolysis in another organism [GO:0051715]; pore complex assembly [GO:0046931] GO:0005576; GO:0006812; GO:0015267; GO:0042151; GO:0044218; GO:0046930; GO:0046931; GO:0051715; GO:0090729 40600 XM_029324178.2 487 294 249 360 294 Q0P595 4.2e-140 NAD-dependent protein deacetylase sirtuin-7 (EC 2.3.1.286) (NAD-dependent protein deacylase sirtuin-7) (EC 2.3.1.-) (Regulatory protein SIR2 homolog 7) (SIR2-like protein 7) Bos taurus (Bovine) DNA repair [GO:0006281]; DNA repair-dependent chromatin remodeling [GO:0140861]; histone H3 deacetylation [GO:0070932]; homologous chromosome pairing at meiosis [GO:0007129]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transposition [GO:0010529]; osteoblast differentiation [GO:0001649]; positive regulation of rRNA processing [GO:2000234]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of transcription involved in exit from mitosis [GO:0007072]; protein deacetylation [GO:0006476]; protein deglutarylation [GO:0061698]; protein depropionylation [GO:0106230]; R-loop processing [GO:0062176]; regulation of double-strand break repair via nonhomologous end joining [GO:2001032]; regulation of gluconeogenesis [GO:0006111]; regulation of mitochondrion organization [GO:0010821]; regulation of protein export from nucleus [GO:0046825]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901836]; rRNA transcription [GO:0009303] GO:0000122; GO:0000785; GO:0001649; GO:0003682; GO:0003714; GO:0004407; GO:0005634; GO:0005730; GO:0005731; GO:0005737; GO:0006111; GO:0006281; GO:0006357; GO:0006476; GO:0007072; GO:0007129; GO:0009303; GO:0010529; GO:0010821; GO:0016607; GO:0019213; GO:0031397; GO:0034979; GO:0035861; GO:0036055; GO:0045943; GO:0046825; GO:0046872; GO:0061697; GO:0061698; GO:0062176; GO:0070403; GO:0070932; GO:0097372; GO:0106230; GO:0106231; GO:0140861; GO:1901836; GO:2000234; GO:2001032 40601 XM_044309322.1 4 0 0 8 0 NA NA NA NA NA NA 40602 XM_029357065.2 0 0 0 71 0 NA NA NA NA NA NA 40603 XM_029347622.2 2 0 2 9 6 Q5SVZ6 2.9e-55 Zinc finger MYM-type protein 1 Homo sapiens (Human) NA GO:0005634; GO:0008270; GO:0046983 40604 XM_029336576.2 0 843 746 1311 1763 NA NA NA NA NA NA 40605 XR_006391376.1 22 4 0 29 4 NA NA NA NA NA NA 40606 XM_029351249.2 10333 5830 4167 5836 4984 NA NA NA NA NA NA 40607 XM_044308713.1 62 724 659 1252 330 NA NA NA NA NA NA 40608 XM_029324798.2 0 22 3 15 0 NA NA NA NA NA NA 40609 XM_044323032.1 33 4 0 20 46 NA NA NA NA NA NA 40610 XM_044309706.1 131 1 73 56 118 NA NA NA NA NA NA 40611 XM_029332724.2 5450 3354 2734 4742 4089 Q8WY21 5.54e-102 VPS10 domain-containing receptor SorCS1 (hSorCS) Homo sapiens (Human) neuropeptide signaling pathway [GO:0007218]; post-Golgi vesicle-mediated transport [GO:0006892] GO:0005794; GO:0006892; GO:0007218; GO:0008188; GO:0016020 40612 XM_029326768.2 549 141 246 378 622 NA NA NA NA NA NA 40613 XM_044326916.1 3 0 2 11 2 NA NA NA NA NA NA 40614 XM_029346388.2 171 159 65 0 207 Q58EX7 3.44e-135 Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (PH domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1) Homo sapiens (Human) regulation of small GTPase mediated signal transduction [GO:0051056] GO:0005085; GO:0005829; GO:0051056 40615 XM_044313946.1 8 0 4 4 21 B8VIU6 1.69e-64 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 40616 XM_044323105.1 198 72 82 131 62 Q90419 1.61e-96 Tiggy-winkle hedgehog protein (TWHH) (EC 3.1.-.-) (Sonic hedgehog protein B) (SHHB) [Cleaved into: Tiggy-winkle hedgehog protein N-product (Shh N-terminal processed signaling domains) (ShhNp) (Sonic hedgehog protein N-product) (ShhN)] Danio rerio (Zebrafish) (Brachydanio rerio) cell fate specification [GO:0001708]; cell-cell signaling [GO:0007267]; embryonic neurocranium morphogenesis [GO:0048702]; embryonic viscerocranium morphogenesis [GO:0048703]; endocardial cell differentiation [GO:0060956]; forebrain development [GO:0030900]; gliogenesis [GO:0042063]; neuron differentiation [GO:0030182]; neuron fate commitment [GO:0048663]; oligodendrocyte differentiation [GO:0048709]; positive regulation of smoothened signaling pathway [GO:0045880]; protein autoprocessing [GO:0016540]; regulation of gene expression [GO:0010468]; self proteolysis [GO:0097264]; smoothened signaling pathway [GO:0007224]; striated muscle cell development [GO:0055002] GO:0000139; GO:0001708; GO:0005113; GO:0005509; GO:0005615; GO:0005789; GO:0005886; GO:0007224; GO:0007267; GO:0008233; GO:0010468; GO:0016540; GO:0030182; GO:0030900; GO:0042063; GO:0045880; GO:0048663; GO:0048702; GO:0048703; GO:0048709; GO:0055002; GO:0060956; GO:0097264; GO:0140853 40617 XM_029324491.2 4331 3915 3053 3368 3069 O35130 4.83e-104 Ribosomal RNA small subunit methyltransferase NEP1 (EC 2.1.1.-) (18S rRNA (pseudouridine(1248)-N1)-methyltransferase) (18S rRNA Psi1248 methyltransferase) (Nucleolar protein EMG1 homolog) (Protein C2f) (Ribosome biogenesis protein NEP1) Mus musculus (Mouse) blastocyst development [GO:0001824]; nucleologenesis [GO:0017126]; rRNA base methylation [GO:0070475] GO:0001824; GO:0005654; GO:0005694; GO:0005730; GO:0017126; GO:0019843; GO:0032040; GO:0042802; GO:0070037; GO:0070475 40618 XM_029350286.2 112 31 23 104 0 Q6L8F3 2.74e-32 NA NA NA NA 40619 XM_029330500.2 349 140 83 278 86 NA NA NA NA NA NA 40620 XM_029324044.2 0 7 0 0 3 Q09575 2.06e-21 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 40621 XM_044326469.1 512 448 354 535 655 NA NA NA NA NA NA 40622 XM_029326537.2 141 7 10 1 274 NA NA NA NA NA NA 40623 XM_029346825.2 431 346 314 456 733 Q9ULL1 1.33e-94 Pleckstrin homology domain-containing family G member 1 Homo sapiens (Human) regulation of small GTPase mediated signal transduction [GO:0051056] GO:0005085; GO:0005654; GO:0005829; GO:0051056 40624 XM_044313611.1 0 0 0 13 0 NA NA NA NA NA NA 40625 XM_044306776.1 0 170 0 68 0 NA NA NA NA NA NA 40626 XM_029332726.2 464 641 344 482 535 Q9P287 3.64e-33 BRCA2 and CDKN1A-interacting protein (P21- and CDK-associated protein 1) (Protein TOK-1) Homo sapiens (Human) DNA repair [GO:0006281]; establishment of mitotic spindle orientation [GO:0000132]; microtubule anchoring [GO:0034453]; microtubule cytoskeleton organization [GO:0000226]; mitotic spindle assembly [GO:0090307]; mitotic spindle organization [GO:0007052]; neuroendocrine cell differentiation [GO:0061101]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079] GO:0000079; GO:0000132; GO:0000226; GO:0003723; GO:0005634; GO:0005654; GO:0005813; GO:0005814; GO:0005829; GO:0006281; GO:0007052; GO:0015631; GO:0019207; GO:0019908; GO:0034453; GO:0061101; GO:0090307; GO:0097431 40627 XM_029339108.2 545 139 44 214 287 Q3TZ87 1.22e-22 E3 ubiquitin-protein ligase MARCHF9 (EC 2.3.2.27) (Membrane-associated RING finger protein 9) (Membrane-associated RING-CH protein IX) (MARCH-IX) (RING-type E3 ubiquitin transferase MARCHF9) Mus musculus (Mouse) NA GO:0000139; GO:0004842; GO:0005765; GO:0005795; GO:0005802; GO:0008270 40628 XM_044323430.1 6 0 10 4 6 NA NA NA NA NA NA 40629 XM_029342935.2 78 62 0 216 192 NA NA NA NA NA NA 40630 XM_029326385.2 20 35 122 102 268 NA NA NA NA NA NA 40631 XM_029355867.2 450 144 206 125 216 NA NA NA NA NA NA 40632 XM_029330294.2 673 52 1118 477 1182 P41247 7.21e-76 Patatin-like phospholipase domain-containing protein 4 (EC 3.1.1.3) (Calcium-independent phospholipase A2-eta) (iPLA2-eta) (EC 3.1.1.4) (Protein GS2) Homo sapiens (Human) lipid homeostasis [GO:0055088]; triglyceride catabolic process [GO:0019433] GO:0004623; GO:0004806; GO:0005737; GO:0005739; GO:0005811; GO:0005829; GO:0016020; GO:0016411; GO:0019433; GO:0047376; GO:0050253; GO:0051264; GO:0051265; GO:0055088 40633 XM_029344422.2 67 61 15 93 41 NA NA NA NA NA NA 40634 XM_029349270.2 699 6 0 691 910 Q9UHJ3 8.05e-83 Scm-like with four MBT domains protein 1 (hSFMBT) (Renal ubiquitous protein 1) Homo sapiens (Human) cell differentiation [GO:0030154]; chromatin organization [GO:0006325]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of muscle organ development [GO:0048635]; spermatogenesis [GO:0007283] GO:0003682; GO:0003714; GO:0005634; GO:0005654; GO:0006325; GO:0007283; GO:0030154; GO:0042393; GO:0045892; GO:0048635 40635 XM_044311295.1 16 10 15 13 21 Q91W78 1.19e-29 U6 snRNA phosphodiesterase 1 (3'-5' RNA exonuclease USB1) (EC 4.6.1.-) Mus musculus (Mouse) RNA splicing [GO:0008380]; snRNA 3'-end processing [GO:0034472]; U6 snRNA 3'-end processing [GO:0034477] GO:0000175; GO:0005634; GO:0005654; GO:0008380; GO:0016829; GO:0034472; GO:0034477; GO:0045171; GO:1990838 40636 XM_044322600.1 47 54 72 5 194 O43854 5.45e-24 EGF-like repeat and discoidin I-like domain-containing protein 3 (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1) Homo sapiens (Human) cell adhesion [GO:0007155]; positive regulation of cell-substrate adhesion [GO:0010811] GO:0005178; GO:0005509; GO:0007155; GO:0010811; GO:0062023; GO:0070062; GO:1903561 40637 XM_044322600.1 47 54 72 5 194 O43854 1.66e-23 EGF-like repeat and discoidin I-like domain-containing protein 3 (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1) Homo sapiens (Human) cell adhesion [GO:0007155]; positive regulation of cell-substrate adhesion [GO:0010811] GO:0005178; GO:0005509; GO:0007155; GO:0010811; GO:0062023; GO:0070062; GO:1903561 40638 XM_044328833.1 354 751 260 596 0 Q6AX59 9.75e-70 Protein ABHD8 (EC 3.-.-.-) (Alpha/beta hydrolase domain-containing protein 8) (Abhydrolase domain-containing protein 8) Xenopus laevis (African clawed frog) NA GO:0016787 40639 XM_044327366.1 692 603 488 661 876 NA NA NA NA NA NA 40640 XM_044321844.1 433 384 585 355 258 Q5ZJ65 1.19e-57 Protein FAM76A Gallus gallus (Chicken) NA GO:0005654; GO:0016607 40641 XM_029335489.2 44 4 67 6 104 NA NA NA NA NA NA 40642 XM_029325983.2 0 10 4 0 147 NA NA NA NA NA NA 40643 XR_006393485.1 35 0 9 40 36 NA NA NA NA NA NA 40644 XM_029350673.2 1334 0 217 127 1348 P54288 2.95e-125 Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2) Oryctolagus cuniculus (Rabbit) calcium ion import [GO:0070509]; chemical synaptic transmission [GO:0007268]; membrane depolarization during atrial cardiac muscle cell action potential [GO:0098912]; positive regulation of calcium ion transport [GO:0051928]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ion transmembrane transport [GO:0034765]; visual perception [GO:0007601] GO:0007268; GO:0007601; GO:0008331; GO:0034765; GO:0051015; GO:0051928; GO:0070509; GO:0086056; GO:0086091; GO:0098684; GO:0098793; GO:0098912; GO:0099626; GO:1990454 40645 XM_044313107.1 77 51 6 80 138 NA NA NA NA NA NA 40646 XM_029352380.2 61 275 64 167 93 Q3TIT8 1.2e-155 Sugar phosphate exchanger 3 (Solute carrier family 37 member 3) Mus musculus (Mouse) carbohydrate transport [GO:0008643] GO:0005789; GO:0008643; GO:0022857 40647 XR_006396940.1 278 73 186 94 920 NA NA NA NA NA NA 40648 XM_044319431.1 19 30 115 0 57 NA NA NA NA NA NA 40649 XM_044327756.1 0 0 0 11 0 NA NA NA NA NA NA 40650 XR_003823267.2 14 0 7 0 0 NA NA NA NA NA NA 40651 XM_044313384.1 0 0 0 0 8 NA NA NA NA NA NA 40652 XM_029358454.2 27 6 10 6 15 Q05941 5.31e-78 Neuronal acetylcholine receptor subunit alpha-7 Rattus norvegicus (Rat) acetylcholine receptor signaling pathway [GO:0095500]; associative learning [GO:0008306]; B cell activation [GO:0042113]; behavioral response to ethanol [GO:0048149]; behavioral response to nicotine [GO:0035095]; calcium ion transport [GO:0006816]; cation transmembrane transport [GO:0098655]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; cognition [GO:0050890]; dendrite arborization [GO:0140059]; dendritic spine organization [GO:0097061]; dopamine biosynthetic process [GO:0042416]; endocytosis [GO:0006897]; establishment of localization in cell [GO:0051649]; excitatory postsynaptic potential [GO:0060079]; flagellated sperm motility [GO:0030317]; generation of ovulation cycle rhythm [GO:0060112]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; learning or memory [GO:0007611]; membrane depolarization [GO:0051899]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; modulation of excitatory postsynaptic potential [GO:0098815]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of tumor necrosis factor production [GO:0032720]; nervous system process [GO:0050877]; neuronal action potential [GO:0019228]; ovulation cycle [GO:0042698]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of CoA-transferase activity [GO:1905920]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure [GO:0001988]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of amyloid fibril formation [GO:1905906]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of inflammatory response [GO:0050727]; regulation of membrane potential [GO:0042391]; regulation of neuron death [GO:1901214]; regulation of nitric oxide metabolic process [GO:0080164]; regulation of norepinephrine secretion [GO:0014061]; regulation of response to drug [GO:2001023]; regulation of synaptic transmission, dopaminergic [GO:0032225]; response to acetylcholine [GO:1905144]; response to amyloid-beta [GO:1904645]; response to carbamate [GO:0046681]; response to cold [GO:0009409]; response to ethanol [GO:0045471]; response to food [GO:0032094]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; sensory processing [GO:0050893]; signal transduction [GO:0007165]; synapse organization [GO:0050808]; synaptic transmission, cholinergic [GO:0007271]; T cell activation [GO:0042110] GO:0001540; GO:0001666; GO:0001933; GO:0001934; GO:0001988; GO:0005216; GO:0005231; GO:0005737; GO:0005886; GO:0005892; GO:0006811; GO:0006816; GO:0006874; GO:0006897; GO:0007165; GO:0007268; GO:0007271; GO:0007611; GO:0007613; GO:0008179; GO:0008284; GO:0008306; GO:0009409; GO:0009897; GO:0010628; GO:0014061; GO:0014069; GO:0015464; GO:0015643; GO:0016020; GO:0016324; GO:0017081; GO:0019228; GO:0019901; GO:0022848; GO:0030317; GO:0030424; GO:0030425; GO:0030426; GO:0030594; GO:0030673; GO:0032094; GO:0032225; GO:0032279; GO:0032691; GO:0032715; GO:0032720; GO:0033138; GO:0034220; GO:0035094; GO:0035095; GO:0042110; GO:0042113; GO:0042166; GO:0042391; GO:0042416; GO:0042698; GO:0042734; GO:0042803; GO:0043005; GO:0043025; GO:0043197; GO:0043198; GO:0043410; GO:0044853; GO:0045121; GO:0045202; GO:0045211; GO:0045471; GO:0045766; GO:0046681; GO:0048149; GO:0050727; GO:0050728; GO:0050804; GO:0050808; GO:0050877; GO:0050890; GO:0050893; GO:0051117; GO:0051247; GO:0051649; GO:0051899; GO:0060079; GO:0060112; GO:0070373; GO:0070374; GO:0080164; GO:0095500; GO:0097061; GO:0097110; GO:0098655; GO:0098690; GO:0098815; GO:0098897; GO:0098981; GO:0099171; GO:0099634; GO:0140059; GO:1900273; GO:1901214; GO:1902004; GO:1902430; GO:1902991; GO:1904315; GO:1904645; GO:1905144; GO:1905906; GO:1905920; GO:2000463; GO:2001023 40653 XM_029340928.2 96 28 15 103 48 NA NA NA NA NA NA 40654 XM_029346937.2 87 69 106 182 138 NA NA NA NA NA NA 40655 XM_029351682.2 3229 3084 2252 1036 2071 Q8VIG3 7.49e-74 Radial spoke head 1 homolog (Male meiotic metaphase chromosome-associated acidic protein) (Meichroacidin) (Testis-specific gene A2 protein) Mus musculus (Mouse) axoneme assembly [GO:0035082]; meiotic cell cycle [GO:0051321]; spermatid development [GO:0007286] GO:0000794; GO:0001520; GO:0005634; GO:0005737; GO:0005829; GO:0005929; GO:0007286; GO:0031514; GO:0035082; GO:0036126; GO:0051321; GO:0072687 40656 XM_029348740.2 0 6 0 0 0 NA NA NA NA NA NA 40657 XM_044313343.1 3624 3295 2708 2730 2996 O93327 1.64e-125 Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (H2A.y) (H2A/y) Gallus gallus (Chicken) nucleosome assembly [GO:0006334]; regulation of NAD metabolic process [GO:1902688] GO:0000786; GO:0003677; GO:0005634; GO:0006334; GO:0030527; GO:0046982; GO:0072570; GO:0160002; GO:1902688 40658 XR_003824270.2 21 27 46 93 59 NA NA NA NA NA NA 40659 XM_029346602.2 1154 730 1114 1443 2380 NA NA NA NA NA NA 40660 XM_029342036.2 0 0 0 0 58 Q90683 1.19e-35 Transcription factor 4 (TCF-4) (Class A helix-loop-helix transcription factor GE2) Gallus gallus (Chicken) positive regulation of neuron differentiation [GO:0045666]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005667; GO:0006357; GO:0045666; GO:0046982; GO:0070888 40661 XM_029331824.2 17125 15255 8223 13239 9300 Q5U2U2 1.22e-51 Crk-like protein Rattus norvegicus (Rat) acetylcholine receptor signaling pathway [GO:0095500]; activation of GTPase activity [GO:0090630]; animal organ morphogenesis [GO:0009887]; anterior/posterior pattern specification [GO:0009952]; B cell apoptotic process [GO:0001783]; blood vessel development [GO:0001568]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cellular response to interleukin-7 [GO:0098761]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cellular response to xenobiotic stimulus [GO:0071466]; cerebellar neuron development [GO:0098749]; cerebral cortex development [GO:0021987]; cranial skeletal system development [GO:1904888]; dendrite development [GO:0016358]; endothelin receptor signaling pathway [GO:0086100]; establishment of cell polarity [GO:0030010]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart development [GO:0007507]; helper T cell diapedesis [GO:0035685]; hippocampus development [GO:0021766]; lipid metabolic process [GO:0006629]; male gonad development [GO:0008584]; negative regulation of gene expression [GO:0010629]; negative regulation of protein phosphorylation [GO:0001933]; neuron migration [GO:0001764]; outflow tract morphogenesis [GO:0003151]; parathyroid gland development [GO:0060017]; pattern specification process [GO:0007389]; pharynx development [GO:0060465]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glial cell migration [GO:1903977]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; postsynaptic specialization assembly [GO:0098698]; reelin-mediated signaling pathway [GO:0038026]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell growth [GO:0001558]; regulation of dendrite development [GO:0050773]; regulation of gene expression [GO:0010468]; regulation of leukocyte migration [GO:0002685]; regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904393]; regulation of T cell migration [GO:2000404]; response to fibroblast growth factor [GO:0071774]; retinoic acid receptor signaling pathway [GO:0048384]; signal transduction [GO:0007165]; single fertilization [GO:0007338]; spermatogenesis [GO:0007283]; synapse assembly [GO:0007416]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; urogenital system development [GO:0001655] GO:0001558; GO:0001568; GO:0001655; GO:0001764; GO:0001783; GO:0001784; GO:0001933; GO:0001934; GO:0002685; GO:0003151; GO:0005654; GO:0005737; GO:0005829; GO:0006629; GO:0007165; GO:0007283; GO:0007338; GO:0007389; GO:0007416; GO:0007507; GO:0008284; GO:0008543; GO:0008584; GO:0009887; GO:0009952; GO:0010468; GO:0010629; GO:0016358; GO:0016477; GO:0021766; GO:0021987; GO:0030010; GO:0030971; GO:0031594; GO:0032991; GO:0033628; GO:0035591; GO:0035685; GO:0038026; GO:0042802; GO:0043410; GO:0045202; GO:0048384; GO:0048538; GO:0050773; GO:0050852; GO:0060017; GO:0060326; GO:0060465; GO:0061629; GO:0070374; GO:0071466; GO:0071560; GO:0071774; GO:0086100; GO:0090630; GO:0095500; GO:0098698; GO:0098749; GO:0098761; GO:0098890; GO:1900026; GO:1903977; GO:1904393; GO:1904888; GO:2000404 40662 XM_044307467.1 16 0 0 0 0 NA NA NA NA NA NA 40663 XM_044322452.1 2 15 36 5 22 NA NA NA NA NA NA 40664 XM_029350091.2 1846 881 681 1719 1684 P56941 0 NPC intracellular cholesterol transporter 1 (Niemann-Pick C1 protein) Sus scrofa (Pig) bile acid metabolic process [GO:0008206]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; cholesterol transport [GO:0030301]; intestinal cholesterol absorption [GO:0030299]; intracellular cholesterol transport [GO:0032367]; lysosomal transport [GO:0007041]; negative regulation of TORC1 signaling [GO:1904262]; protein glycosylation [GO:0006486]; sterol transport [GO:0015918] GO:0005319; GO:0005576; GO:0005635; GO:0005764; GO:0005765; GO:0005783; GO:0005886; GO:0006486; GO:0007041; GO:0008203; GO:0008206; GO:0015485; GO:0015918; GO:0016020; GO:0030299; GO:0030301; GO:0031902; GO:0032367; GO:0032934; GO:0042632; GO:0048471; GO:1904262 40665 XM_044320720.1 179 199 140 248 220 Q9NZJ4 0 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 40666 XM_044320720.1 179 199 140 248 220 Q9NZJ4 3.65e-46 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 40667 XR_006396183.1 0 0 6 0 15 NA NA NA NA NA NA 40668 XR_006392549.1 122 54 231 79 818 NA NA NA NA NA NA 40669 XM_044327512.1 73 0 0 325 81 NA NA NA NA NA NA 40670 XM_029340239.2 124 143 0 103 27 NA NA NA NA NA NA 40671 XM_044325562.1 0 0 0 0 9 NA NA NA NA NA NA 40672 XM_029347151.2 6 2 10 6 23 P30974 2.46e-27 Tachykinin-like peptides receptor 86C (NKD) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; inter-male aggressive behavior [GO:0002121]; neuropeptide signaling pathway [GO:0007218]; tachykinin receptor signaling pathway [GO:0007217] GO:0002121; GO:0004995; GO:0005886; GO:0007186; GO:0007217; GO:0007218; GO:0008188; GO:0016020 40673 XM_029338613.2 85 10 22 101 68 Q6P4M0 2.38e-143 7-dehydrocholesterol reductase (7-DHC reductase) (EC 1.3.1.21) (Sterol Delta(7)-reductase) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cholesterol biosynthetic process [GO:0006695] GO:0005789; GO:0006695; GO:0047598; GO:0050661 40674 XM_029342684.2 31811 36116 13856 19211 9711 Q5ZJF4 1.41e-109 Peroxiredoxin-6 (EC 1.11.1.27) (1-Cys peroxiredoxin) (1-Cys PRX) (Acidic calcium-independent phospholipase A2) (aiPLA2) (EC 3.1.1.4) (Glutathione-dependent peroxiredoxin) (Lysophosphatidylcholine acyltransferase 5) (LPC acyltransferase 5) (LPCAT-5) (Lyso-PC acyltransferase 5) (EC 2.3.1.23) (Non-selenium glutathione peroxidase) (NSGPx) Gallus gallus (Chicken) cell redox homeostasis [GO:0045454]; lipid catabolic process [GO:0016042] GO:0004623; GO:0005615; GO:0005739; GO:0005764; GO:0005829; GO:0016042; GO:0045454; GO:0047184; GO:0051920 40675 XM_029338080.2 151 158 133 142 220 Q5RFD0 4.33e-41 2',3'-cyclic-nucleotide 3'-phosphodiesterase (CNP) (CNPase) (EC 3.1.4.37) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cyclic nucleotide catabolic process [GO:0009214] GO:0003723; GO:0004113; GO:0009214; GO:0016020; GO:0042470 40676 XR_006397043.1 106 226 60 191 330 Q8BR76 5.98e-34 Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67) Mus musculus (Mouse) branching morphogenesis of an epithelial tube [GO:0048754]; cilium assembly [GO:0060271]; determination of left/right symmetry [GO:0007368]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; head development [GO:0060322]; heart development [GO:0007507]; kidney development [GO:0001822]; negative regulation of centrosome duplication [GO:0010826]; non-canonical Wnt signaling pathway [GO:0035567]; photoreceptor cell outer segment organization [GO:0035845]; positive regulation of ERAD pathway [GO:1904294]; positive regulation of non-motile cilium assembly [GO:1902857]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0001822; GO:0005789; GO:0005813; GO:0005886; GO:0005929; GO:0005930; GO:0007368; GO:0007507; GO:0010826; GO:0030433; GO:0030659; GO:0031005; GO:0035567; GO:0035845; GO:0035869; GO:0036038; GO:0048754; GO:0051082; GO:0051787; GO:0060170; GO:0060271; GO:0060322; GO:0060441; GO:1902857; GO:1904294 40677 XR_003827942.2 75 229 134 198 170 NA NA NA NA NA NA 40678 XM_029356132.2 156 123 34 270 336 Q9VCA2 2.06e-59 Organic cation transporter protein Drosophila melanogaster (Fruit fly) apoptotic process [GO:0006915]; ion transport [GO:0006811] GO:0006811; GO:0006915; GO:0016020; GO:0022857 40679 XM_029345133.2 15607 18234 6488 6181 6481 NA NA NA NA NA NA 40680 XM_029347875.2 876 763 650 1493 741 Q6UPE1 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial (ETF-QO) (ETF-ubiquinone oxidoreductase) (EC 1.5.5.1) (Electron-transferring-flavoprotein dehydrogenase) (ETF dehydrogenase) Rattus norvegicus (Rat) electron transport chain [GO:0022900]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; response to oxidative stress [GO:0006979] GO:0004174; GO:0005743; GO:0006979; GO:0009055; GO:0016491; GO:0022900; GO:0031966; GO:0033539; GO:0046872; GO:0048038; GO:0048039; GO:0051536; GO:0051539 40681 XM_044323289.1 21 0 25 0 108 Q5R5U3 1.35e-97 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 40682 XM_044323289.1 21 0 25 0 108 Q5R5U3 1.35e-96 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 40683 XM_044323289.1 21 0 25 0 108 Q5R5U3 3.92e-96 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 40684 XM_044323289.1 21 0 25 0 108 Q5R5U3 2.57e-95 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 40685 XM_044323289.1 21 0 25 0 108 Q5R5U3 3.65e-93 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 40686 XM_044323289.1 21 0 25 0 108 Q5R5U3 3.17e-90 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 40687 XM_044323289.1 21 0 25 0 108 Q5R5U3 1.25e-82 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 40688 XM_044323289.1 21 0 25 0 108 Q5R5U3 1.02e-79 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 40689 XM_029324195.2 21 2 4 72 32 NA NA NA NA NA NA 40690 XR_006391337.1 219 240 208 169 88 NA NA NA NA NA NA 40691 XM_044308988.1 113 38 10 229 177 NA NA NA NA NA NA 40692 XM_029330802.2 373 22 88 110 133 NA NA NA NA NA NA 40693 XM_029335126.2 1721 1034 919 1079 958 P05772 0 Protein kinase C beta type (PKC-B) (PKC-beta) (EC 2.7.11.13) Oryctolagus cuniculus (Rabbit) adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; B cell activation [GO:0042113]; B cell receptor signaling pathway [GO:0050853]; chromatin organization [GO:0006325]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; positive regulation of angiogenesis [GO:0045766]; positive regulation of B cell receptor signaling pathway [GO:0050861]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; post-translational protein modification [GO:0043687]; protein phosphorylation [GO:0006468]; regulation of glucose transmembrane transport [GO:0010827]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0002250; GO:0003682; GO:0004697; GO:0004698; GO:0005524; GO:0005634; GO:0005829; GO:0006325; GO:0006357; GO:0006468; GO:0006915; GO:0008270; GO:0010827; GO:0010829; GO:0016020; GO:0030374; GO:0030949; GO:0035403; GO:0042113; GO:0042393; GO:0043123; GO:0043687; GO:0045766; GO:0046627; GO:0050681; GO:0050853; GO:0050861; GO:0051092; GO:0106310 40694 XM_029345122.2 25 0 10 3 20 NA NA NA NA NA NA 40695 XM_029336383.2 598 259 368 231 330 NA NA NA NA NA NA 40696 XR_006391407.1 0 0 0 0 16 NA NA NA NA NA NA 40697 XM_044318543.1 5 23 0 0 9 O75899 5.9e-91 Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51) (HG20) Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway [GO:0007186]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; neuron-glial cell signaling [GO:0150099]; synaptic transmission, GABAergic [GO:0051932] GO:0004888; GO:0004965; GO:0005737; GO:0005886; GO:0007186; GO:0007193; GO:0007194; GO:0007214; GO:0007268; GO:0038039; GO:0043005; GO:0045211; GO:0046982; GO:0051932; GO:0150099; GO:1902710; GO:1902712 40698 XM_044324791.1 252 345 192 242 250 G3V9H8 5.28e-81 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Rattus norvegicus (Rat) cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0007156; GO:0007158; GO:0007169; GO:0007399; GO:0009410; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030182; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0098797 40699 XM_029341631.2 642 670 409 372 570 NA NA NA NA NA NA 40700 XM_029332835.2 169 48 0 98 103 Q6GQN8 6.95e-101 Enoyl-[acyl-carrier-protein] reductase, mitochondrial (EC 1.3.1.104) (2-enoyl thioester reductase) Danio rerio (Zebrafish) (Brachydanio rerio) fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631] GO:0005739; GO:0006631; GO:0006633; GO:0019166 40701 XM_029332139.2 51576 98374 36539 86641 49181 NA NA NA NA NA NA 40702 XM_044319889.1 212 56 145 263 491 NA NA NA NA NA NA 40703 XM_044307432.1 206 228 29 538 366 NA NA NA NA NA NA 40704 XM_044325717.1 290 367 128 361 225 NA NA NA NA NA NA 40705 XM_029338261.2 507 629 166 456 500 NA NA NA NA NA NA 40706 XM_044323235.1 9 11 0 0 1 NA NA NA NA NA NA 40707 XM_029337714.2 5558 6366 2583 4737 3578 Q9C0D7 1.2e-82 Probable ribonuclease ZC3H12C (EC 3.1.-.-) (MCP-induced protein 3) (Zinc finger CCCH domain-containing protein 12C) Homo sapiens (Human) RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502] GO:0003729; GO:0004521; GO:0005634; GO:0036464; GO:0046872; GO:0090502 40708 XM_044310921.1 0 0 0 6 0 NA NA NA NA NA NA 40709 XM_029327944.2 1 0 7 0 47 NA NA NA NA NA NA 40710 XR_006394898.1 22 0 52 54 17 NA NA NA NA NA NA 40711 XM_029351557.2 337 117 125 199 120 O42574 1.4e-23 Beta-1 adrenergic receptor (Beta-1 adrenoreceptor) (Beta-1 adrenoceptor) (x-BETA1AR) Xenopus laevis (African clawed frog) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; positive regulation of GTPase activity [GO:0043547]; positive regulation of heart contraction [GO:0045823] GO:0004940; GO:0005085; GO:0005769; GO:0005886; GO:0043547; GO:0045823; GO:0071880 40712 XM_044326052.1 33 15 165 32 204 NA NA NA NA NA NA 40713 XR_006392403.1 107 48 45 147 74 NA NA NA NA NA NA 40714 XM_029340131.2 337 168 140 183 231 NA NA NA NA NA NA 40715 XM_029335121.2 48 25 137 122 67 Q20191 4.08e-44 Zinc metalloproteinase nas-13 (EC 3.4.24.-) (Nematode astacin 13) Caenorhabditis elegans proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0006508; GO:0008270 40716 XR_003827576.2 1 0 0 6 0 NA NA NA NA NA NA 40717 XM_044311420.1 22 5 21 12 23 NA NA NA NA NA NA 40718 XM_044321039.1 50 157 27 0 0 C3ZQF9 5.98e-30 QRFP-like peptide receptor Branchiostoma floridae (Florida lancelet) (Amphioxus) cellular response to peptide [GO:1901653]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:1901653 40719 XM_044312010.1 156 8 0 0 0 Q95LR0 9.28e-53 Cilia- and flagella-associated protein 91 (CFAP91) (AMY-1-associating protein expressed in testis 1) (AAT-1) (MYCBP/AMY-1-associated testis-expressed protein 1) (Protein MAATS1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) axonemal central apparatus assembly [GO:1904158]; cell differentiation [GO:0030154]; cilium movement [GO:0003341]; spermatogenesis [GO:0007283] GO:0003341; GO:0005739; GO:0005930; GO:0007283; GO:0030154; GO:0031514; GO:1904158 40720 XM_029331586.2 54 18 3 42 10 NA NA NA NA NA NA 40721 XM_044313630.1 27 9 1 15 0 Q8N531 1.27e-26 F-box/LRR-repeat protein 6 (F-box and leucine-rich repeat protein 6) (F-box protein FBL6) (FBL6A) Homo sapiens (Human) entrainment of circadian clock by photoperiod [GO:0043153]; G2/M transition of mitotic cell cycle [GO:0000086]; proteolysis [GO:0006508]; regulation of cell cycle [GO:0051726]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0000086; GO:0004842; GO:0005634; GO:0005829; GO:0006508; GO:0019005; GO:0031146; GO:0043153; GO:0051726 40722 XM_044311210.1 135 100 102 132 84 NA NA NA NA NA NA 40723 XM_029334998.2 3103 3638 1654 2079 706 NA NA NA NA NA NA 40724 XM_029346747.2 587 427 529 953 922 Q91574 2.47e-26 ALX homeobox protein 1 (Cartilage homeoprotein 1) (CART-1) (XCART1) Xenopus laevis (African clawed frog) positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial to mesenchymal transition [GO:0010718] GO:0000981; GO:0003677; GO:0005634; GO:0010718; GO:0045893 40725 XM_044309266.1 0 0 8 0 12 NA NA NA NA NA NA 40726 XM_029357535.2 441 179 217 302 794 A7SBF0 0 Integrator complex subunit 9 homolog Nematostella vectensis (Starlet sea anemone) snRNA 3'-end processing [GO:0034472] GO:0032039; GO:0034472 40727 XM_044310270.1 115 0 0 0 17 NA NA NA NA NA NA 40728 XM_029352741.2 0 161 180 100 296 Q9H0J9 2.5e-23 Protein mono-ADP-ribosyltransferase PARP12 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 12) (ARTD12) (Poly [ADP-ribose] polymerase 12) (PARP-12) (Zinc finger CCCH domain-containing protein 1) Homo sapiens (Human) protein auto-ADP-ribosylation [GO:0070213] GO:0003723; GO:0003950; GO:0005634; GO:0016779; GO:0046872; GO:0070213; GO:0140803; GO:1990404 40729 XR_006396242.1 398 92 54 87 230 NA NA NA NA NA NA 40730 XM_044315528.1 129 403 259 318 337 NA NA NA NA NA NA 40731 XM_029324179.2 363 251 223 426 399 Q9Y3B9 3.55e-24 RRP15-like protein (Ribosomal RNA-processing protein 15) Homo sapiens (Human) maturation of 5.8S rRNA [GO:0000460]; maturation of LSU-rRNA [GO:0000470] GO:0000460; GO:0000470; GO:0030687 40732 XM_029346655.2 82 0 30 8 8 NA NA NA NA NA NA 40733 XM_044313097.1 12 93 17 60 16 NA NA NA NA NA NA 40734 XM_029342056.2 3327 5928 2379 3713 3101 Q9D8V7 6.99e-102 Signal peptidase complex catalytic subunit SEC11C (EC 3.4.21.89) (Microsomal signal peptidase 21 kDa subunit) (SPase 21 kDa subunit) (SEC11 homolog C) (SEC11-like protein 3) (SPC21) Mus musculus (Mouse) signal peptide processing [GO:0006465] GO:0004252; GO:0005787; GO:0006465; GO:0008233 40735 XM_044315920.1 0 13 4 0 0 NA NA NA NA NA NA 40736 XR_006397808.1 0 34 0 0 8 NA NA NA NA NA NA 40737 XR_006392496.1 127 319 119 349 213 NA NA NA NA NA NA 40738 XM_029332992.2 23 45 0 41 46 Q3UZD5 1.63e-97 Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.361) (PR domain zinc finger protein 6) (PR domain-containing protein 6) (PR domain-containing protein in smooth muscle) Mus musculus (Mouse) chromatin organization [GO:0006325]; histone methylation [GO:0016571]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of smooth muscle cell differentiation [GO:0051151]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of gene expression [GO:0010468] GO:0000122; GO:0005634; GO:0006325; GO:0010468; GO:0016571; GO:0022008; GO:0042802; GO:0045892; GO:0046872; GO:0051151; GO:0140944 40739 XM_044319026.1 4 6 9 2 38 Q9UHC6 1.77e-33 Contactin-associated protein-like 2 (Cell recognition molecule Caspr2) Homo sapiens (Human) adult behavior [GO:0030534]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell population proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; clustering of voltage-gated potassium channels [GO:0045163]; learning [GO:0007612]; limbic system development [GO:0021761]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuron recognition [GO:0008038]; positive regulation of gap junction assembly [GO:1903598]; protein localization to juxtaparanode region of axon [GO:0071205]; social behavior [GO:0035176]; striatum development [GO:0021756]; superior temporal gyrus development [GO:0071109]; thalamus development [GO:0021794]; transmission of nerve impulse [GO:0019226]; vocal learning [GO:0042297]; vocalization behavior [GO:0071625] GO:0005769; GO:0005794; GO:0007155; GO:0007420; GO:0007612; GO:0008038; GO:0008076; GO:0008283; GO:0009986; GO:0016020; GO:0019226; GO:0019899; GO:0021756; GO:0021761; GO:0021794; GO:0021987; GO:0030424; GO:0030425; GO:0030534; GO:0030673; GO:0031175; GO:0033010; GO:0035176; GO:0042297; GO:0043025; GO:0043204; GO:0044224; GO:0045163; GO:0048812; GO:0071109; GO:0071205; GO:0071625; GO:1903598 40740 XM_029329972.2 392 326 242 415 192 Q8WMS0 1.79e-67 UDP-galactose translocator (Solute carrier family 35 member A2) (UDP-galactose transporter) (UDP-Gal-Tr) (UGT) Canis lupus familiaris (Dog) (Canis familiaris) carbohydrate transport [GO:0008643] GO:0000139; GO:0005459; GO:0008643 40741 XM_029346969.2 1698 1445 1939 3121 2157 NA NA NA NA NA NA 40742 XM_044327794.1 35 6 88 11 363 NA NA NA NA NA NA 40743 XM_029358290.2 3 8 2 13 0 P98072 5.15e-55 Enteropeptidase (EC 3.4.21.9) (Enterokinase) (Serine protease 7) (Transmembrane protease serine 15) [Cleaved into: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain] Bos taurus (Bovine) protein digestion [GO:0044256]; trypsinogen activation [GO:0032023] GO:0004252; GO:0005044; GO:0016020; GO:0032023; GO:0044256 40744 XM_029356526.2 129 97 30 79 63 Q96K19 1.99e-65 E3 ubiquitin-protein ligase RNF170 (EC 2.3.2.27) (Putative LAG1-interacting protein) (RING finger protein 170) (RING-type E3 ubiquitin transferase RNF170) Homo sapiens (Human) NA GO:0005789; GO:0046872; GO:0061630 40745 XM_029357389.2 761 872 465 751 906 Q99LB0 2.62e-49 Deoxynucleotidyltransferase terminal-interacting protein 1 (Terminal deoxynucleotidyltransferase-interacting factor 1) (TdIF1) (TdT-interacting factor 1) Mus musculus (Mouse) NA GO:0000118; GO:0003677; GO:0005634; GO:0005654; GO:0005694; GO:0005730; GO:0008047; GO:0031491; GO:0042803 40746 XR_006393921.1 7 0 0 0 26 NA NA NA NA NA NA 40747 XM_029329718.2 59 90 28 57 86 NA NA NA NA NA NA 40748 XM_044327532.1 6814 2144 2651 5995 4186 NA NA NA NA NA NA 40749 XM_044322228.1 810 453 123 680 458 NA NA NA NA NA NA 40750 XM_029324327.2 135 11 16 44 4 Q9HF54 1.13e-39 GTP-binding protein RHO1 Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii) actin filament organization [GO:0007015]; cortical cytoskeleton organization [GO:0030865]; establishment or maintenance of cell polarity [GO:0007163]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; small GTPase mediated signal transduction [GO:0007264] GO:0003924; GO:0005525; GO:0005856; GO:0005886; GO:0005938; GO:0007015; GO:0007163; GO:0007264; GO:0008360; GO:0019901; GO:0030865; GO:0031410; GO:0032956; GO:0042995 40751 XM_029343804.2 1762 1563 1387 1146 1378 NA NA NA NA NA NA 40752 XR_006393672.1 0 66 0 0 0 NA NA NA NA NA NA 40753 XM_044308136.1 309 492 4 0 8 Q4GZT4 0 Broad substrate specificity ATP-binding cassette transporter ABCG2 (EC 7.6.2.2) (ATP-binding cassette sub-family G member 2) (Urate exporter) (CD antigen CD338) Bos taurus (Bovine) biotin transport [GO:0015878]; lipid transport [GO:0006869]; renal urate salt excretion [GO:0097744]; riboflavin transport [GO:0032218]; transmembrane transport [GO:0055085] GO:0005524; GO:0005886; GO:0006869; GO:0008559; GO:0015143; GO:0015225; GO:0015562; GO:0015878; GO:0016020; GO:0016324; GO:0031526; GO:0031966; GO:0032217; GO:0032218; GO:0042626; GO:0045121; GO:0055085; GO:0097744 40754 XM_044324525.1 101 48 43 64 11 Q09470 1.79e-87 Potassium voltage-gated channel subfamily A member 1 (Voltage-gated K(+) channel HuKI) (Voltage-gated potassium channel HBK1) (Voltage-gated potassium channel subunit Kv1.1) Homo sapiens (Human) axon development [GO:0061564]; cell communication by electrical coupling [GO:0010644]; cellular response to magnesium ion [GO:0071286]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; corpus callosum development [GO:0022038]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; detection of mechanical stimulus involved in sensory perception of touch [GO:0050976]; hippocampus development [GO:0021766]; magnesium ion homeostasis [GO:0010960]; neuroblast proliferation [GO:0007405]; neuromuscular process [GO:0050905]; neuronal action potential [GO:0019228]; neuronal signal transduction [GO:0023041]; optic nerve development [GO:0021554]; positive regulation of voltage-gated potassium channel activity [GO:1903818]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; protein localization [GO:0008104]; regulation of membrane potential [GO:0042391]; regulation of muscle contraction [GO:0006937]; startle response [GO:0001964] GO:0001964; GO:0005249; GO:0005251; GO:0005267; GO:0005783; GO:0005829; GO:0005886; GO:0006813; GO:0006937; GO:0007268; GO:0007405; GO:0008076; GO:0008104; GO:0009986; GO:0010644; GO:0010960; GO:0015079; GO:0016020; GO:0016324; GO:0019228; GO:0021554; GO:0021766; GO:0021987; GO:0022038; GO:0023041; GO:0030054; GO:0030425; GO:0031410; GO:0033270; GO:0042391; GO:0042734; GO:0043025; GO:0043194; GO:0043204; GO:0043679; GO:0044224; GO:0044305; GO:0045202; GO:0045211; GO:0050905; GO:0050966; GO:0050976; GO:0051260; GO:0061564; GO:0070161; GO:0071286; GO:0071805; GO:0097718; GO:0098978; GO:0099508; GO:1903818; GO:1905030 40755 XR_003824910.1 17 3 10 3 13 NA NA NA NA NA NA 40756 XM_044315602.1 1 0 9 5 12 NA NA NA NA NA NA 40757 XM_029349094.2 16738 15453 10511 13670 10719 A7S3J7 2.79e-139 40S ribosomal protein S3a Nematostella vectensis (Starlet sea anemone) translation [GO:0006412] GO:0003735; GO:0005829; GO:0006412; GO:0022627 40758 XM_029332968.2 19946 22783 19740 22452 23401 Q503L9 7.35e-106 Nucleoredoxin (EC 1.8.1.8) Danio rerio (Zebrafish) (Brachydanio rerio) cell differentiation [GO:0030154]; circulatory system development [GO:0072359]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of Wnt signaling pathway [GO:0030178]; Wnt signaling pathway [GO:0016055] GO:0004791; GO:0005634; GO:0005829; GO:0016055; GO:0030154; GO:0030178; GO:0031397; GO:0072359 40759 XR_006392151.1 810 445 145 432 466 Q12933 3.22e-65 TNF receptor-associated factor 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF2) (RING-type E3 ubiquitin transferase TRAF2) (Tumor necrosis factor type 2 receptor-associated protein 3) Homo sapiens (Human) activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular response to nitric oxide [GO:0071732]; interleukin-17-mediated signaling pathway [GO:0097400]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; mRNA stabilization [GO:0048255]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron death [GO:1901215]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein K63-linked ubiquitination [GO:0070534]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin production [GO:0002637]; regulation of protein-containing complex assembly [GO:0043254]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; signal transduction involved in regulation of gene expression [GO:0023019]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000151; GO:0002637; GO:0002726; GO:0002947; GO:0004842; GO:0005164; GO:0005174; GO:0005654; GO:0005829; GO:0005938; GO:0007165; GO:0007250; GO:0008270; GO:0009898; GO:0012506; GO:0019899; GO:0019901; GO:0019903; GO:0023019; GO:0030163; GO:0030674; GO:0031435; GO:0031625; GO:0031996; GO:0032743; GO:0033209; GO:0034351; GO:0034976; GO:0035631; GO:0042802; GO:0042981; GO:0043120; GO:0043122; GO:0043123; GO:0043254; GO:0043507; GO:0044877; GO:0045121; GO:0046330; GO:0046625; GO:0048255; GO:0051091; GO:0051092; GO:0051865; GO:0065003; GO:0070059; GO:0070534; GO:0071732; GO:0097057; GO:0097300; GO:0097400; GO:1901215; GO:1903265; GO:1903721; GO:1990604; GO:2001238 40760 XM_029355836.2 3900 3390 3213 5258 2834 NA NA NA NA NA NA 40761 XM_029349536.2 298 275 159 342 345 NA NA NA NA NA NA 40762 XR_006398176.1 220 197 155 258 298 NA NA NA NA NA NA 40763 XM_029344593.2 341 324 188 302 368 B9M6U2 8.26e-51 50S ribosomal protein L2 Geotalea daltonii (strain DSM 22248 / JCM 15807 / FRC-32) (Geobacter daltonii) translation [GO:0006412] GO:0003735; GO:0006412; GO:0015934; GO:0016740; GO:0019843 40764 XM_029333519.2 0 0 0 0 47 Q9WVF7 0 DNA polymerase epsilon catalytic subunit A (EC 2.7.7.7) (3'-5' exodeoxyribonuclease) (EC 3.1.11.-) (DNA polymerase II subunit A) Mus musculus (Mouse) base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; DNA replication proofreading [GO:0045004]; DNA synthesis involved in DNA repair [GO:0000731]; DNA-templated DNA replication [GO:0006261]; embryonic organ development [GO:0048568]; G1/S transition of mitotic cell cycle [GO:0000082]; leading strand elongation [GO:0006272]; mitotic cell cycle [GO:0000278]; nucleotide-excision repair, DNA gap filling [GO:0006297] GO:0000082; GO:0000166; GO:0000278; GO:0000731; GO:0003677; GO:0003682; GO:0003887; GO:0005634; GO:0005654; GO:0005886; GO:0006260; GO:0006261; GO:0006272; GO:0006287; GO:0006297; GO:0008270; GO:0008310; GO:0008622; GO:0045004; GO:0048568; GO:0051539; GO:0071897 40765 XM_029355373.2 280 123 182 245 303 Q9H477 1.81e-60 Ribokinase (RK) (EC 2.7.1.15) Homo sapiens (Human) D-ribose catabolic process [GO:0019303]; pentose-phosphate shunt [GO:0006098] GO:0004747; GO:0005524; GO:0005634; GO:0005829; GO:0006098; GO:0019303; GO:0042802; GO:0046872 40766 XM_044310177.1 2 0 1 8 6 NA NA NA NA NA NA 40767 XM_029338909.2 137 98 134 91 166 NA NA NA NA NA NA 40768 XM_029349239.2 190 202 87 325 239 Q96FV9 0 THO complex subunit 1 (Tho1) (Nuclear matrix protein p84) (p84N5) (hTREX84) Homo sapiens (Human) apoptotic process [GO:0006915]; mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; negative regulation of DNA damage checkpoint [GO:2000002]; negative regulation of isotype switching to IgA isotypes [GO:0048297]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; regulation of DNA recombination [GO:0000018]; regulation of DNA-templated transcription elongation [GO:0032784]; replication fork processing [GO:0031297]; RNA processing [GO:0006396]; RNA splicing [GO:0008380]; signal transduction [GO:0007165]; viral mRNA export from host cell nucleus [GO:0046784] GO:0000018; GO:0000346; GO:0000347; GO:0000445; GO:0003677; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006396; GO:0006397; GO:0006406; GO:0006915; GO:0007165; GO:0008380; GO:0016363; GO:0016607; GO:0031297; GO:0032784; GO:0032786; GO:0046784; GO:0048297; GO:2000002 40769 XR_006392258.1 9 0 0 0 2 NA NA NA NA NA NA 40770 XM_029336457.2 68 19 90 176 88 NA NA NA NA NA NA 40771 XM_044317585.1 0 0 7 33 0 NA NA NA NA NA NA 40772 XM_044312701.1 0 31 0 7 9 A1L1W9 3.47e-54 Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10) Danio rerio (Zebrafish) (Brachydanio rerio) aromatic amino acid transport [GO:0015801]; thyroid hormone transport [GO:0070327] GO:0005302; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0070327 40773 XM_029356177.2 11 36 19 62 48 Q6P0U3 3.6e-26 Ras-like protein family member 11B (EC 3.6.5.2) Danio rerio (Zebrafish) (Brachydanio rerio) mesendoderm development [GO:0048382] GO:0003925; GO:0005525; GO:0048382 40774 XM_044312246.1 22 4 2 10 38 NA NA NA NA NA NA 40775 XM_044325084.1 114 146 266 114 132 NA NA NA NA NA NA 40776 XM_044325735.1 71 0 26 0 288 NA NA NA NA NA NA 40777 XM_044311184.1 13 3 11 5 7 Q5XXP2 5.32e-26 Melanopsin (Opsin-4) Phodopus sungorus (Striped hairy-footed hamster) (Djungarian hamster) hyaloid vascular plexus regression [GO:1990384]; optokinetic behavior [GO:0007634]; phototransduction [GO:0007602]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511]; visual perception [GO:0007601] GO:0005502; GO:0005886; GO:0007601; GO:0007602; GO:0007634; GO:0008020; GO:0016020; GO:0030424; GO:0030425; GO:0042752; GO:0043204; GO:0048511; GO:1990384 40778 XM_044326726.1 4 0 0 0 19 NA NA NA NA NA NA 40779 XM_044327386.1 157 158 117 334 168 E9Q5F9 1.76e-30 Histone-lysine N-methyltransferase SETD2 (EC 2.1.1.359) (Lysine N-methyltransferase 3A) (Protein-lysine N-methyltransferase SETD2) (EC 2.1.1.-) (SET domain-containing protein 2) Mus musculus (Mouse) angiogenesis [GO:0001525]; cell migration involved in vasculogenesis [GO:0035441]; coronary vasculature morphogenesis [GO:0060977]; defense response to virus [GO:0051607]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic organ development [GO:0048568]; embryonic placenta morphogenesis [GO:0060669]; endodermal cell differentiation [GO:0035987]; forebrain development [GO:0030900]; histone H3-K36 dimethylation [GO:0097676]; histone H3-K36 trimethylation [GO:0097198]; mesoderm morphogenesis [GO:0048332]; microtubule cytoskeleton organization involved in mitosis [GO:1902850]; mismatch repair [GO:0006298]; morphogenesis of a branching structure [GO:0001763]; neural tube closure [GO:0001843]; nucleosome organization [GO:0034728]; peptidyl-lysine trimethylation [GO:0018023]; pericardium development [GO:0060039]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of ossification [GO:0045778]; regulation of cytokinesis [GO:0032465]; regulation of DNA-templated transcription [GO:0006355]; regulation of double-strand break repair via homologous recombination [GO:0010569]; regulation of gene expression [GO:0010468]; regulation of mRNA export from nucleus [GO:0010793]; regulation of protein localization to chromatin [GO:1905634]; response to type I interferon [GO:0034340]; stem cell development [GO:0048864]; stem cell differentiation [GO:0048863]; transcription elongation by RNA polymerase II promoter [GO:0006368]; vasculogenesis [GO:0001570] GO:0001525; GO:0001570; GO:0001763; GO:0001843; GO:0005634; GO:0005694; GO:0006298; GO:0006355; GO:0006368; GO:0010468; GO:0010569; GO:0010793; GO:0016279; GO:0018023; GO:0030900; GO:0032465; GO:0032727; GO:0034340; GO:0034728; GO:0035441; GO:0035987; GO:0043014; GO:0045778; GO:0046872; GO:0046975; GO:0048332; GO:0048568; GO:0048701; GO:0048863; GO:0048864; GO:0051607; GO:0060039; GO:0060669; GO:0060977; GO:0097198; GO:0097676; GO:0140955; GO:1902850; GO:1905634 40780 XM_029358351.2 729 473 565 648 933 F6S215 6.34e-50 AP-5 complex subunit beta-1 (Adaptor-related protein complex 5 beta subunit) (Beta5) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) endosomal transport [GO:0016197]; protein transport [GO:0015031] GO:0015031; GO:0016197; GO:0030119 40781 XR_006396871.1 65 98 107 207 234 NA NA NA NA NA NA 40782 XR_006394194.1 38 0 0 0 0 NA NA NA NA NA NA 40783 XM_044320949.1 467 327 302 383 573 Q9NTJ4 0 Alpha-mannosidase 2C1 (EC 3.2.1.24) (Alpha mannosidase 6A8B) (Alpha-D-mannoside mannohydrolase) (Mannosidase alpha class 2C member 1) Homo sapiens (Human) mannose metabolic process [GO:0006013]; oligosaccharide catabolic process [GO:0009313] GO:0004559; GO:0005654; GO:0005829; GO:0006013; GO:0009313; GO:0030246; GO:0046872 40784 XM_029350045.2 183 72 266 0 66 Q90ZC7 0 Calcium-activated potassium channel subunit alpha-1 (BK channel) (BKCA alpha) (Calcium-activated potassium channel, subfamily M subunit alpha-1) (K(VCA)alpha) (KCa1.1) (Maxi K channel) (MaxiK) (Slo-alpha) (Slo1) (Slowpoke homolog) (Slo homolog) (xSlo) Xenopus laevis (African clawed frog) regulation of ion transmembrane transport [GO:0034765] GO:0005244; GO:0005267; GO:0016020; GO:0034765; GO:0046872 40785 XM_029352040.2 310 121 166 174 247 Q9Y383 2.79e-73 Putative RNA-binding protein Luc7-like 2 Homo sapiens (Human) mRNA splice site selection [GO:0006376] GO:0003723; GO:0003729; GO:0005685; GO:0006376; GO:0016607; GO:0019899; GO:0071004 40786 XM_044329203.1 540 433 453 610 650 Q86SQ7 4.32e-36 Serologically defined colon cancer antigen 8 (Antigen NY-CO-8) (Centrosomal colon cancer autoantigen protein) (hCCCAP) Homo sapiens (Human) cell projection organization [GO:0030030]; centrosome cycle [GO:0007098]; establishment of cell polarity [GO:0030010]; microtubule organizing center organization [GO:0031023]; neuron migration [GO:0001764]; regulation of cilium assembly [GO:1902017]; tube formation [GO:0035148] GO:0001764; GO:0005813; GO:0005814; GO:0005829; GO:0005911; GO:0007098; GO:0030010; GO:0030030; GO:0031023; GO:0034451; GO:0035148; GO:0036064; GO:0097733; GO:1902017 40787 XM_044316402.1 146 78 80 204 127 O97592 1.61e-36 Dystrophin Canis lupus familiaris (Dog) (Canis familiaris) actin cytoskeleton organization [GO:0030036]; muscle cell development [GO:0055001]; neuron development [GO:0048666]; regulation of muscle system process [GO:0090257]; skeletal muscle tissue development [GO:0007519] GO:0005886; GO:0007519; GO:0008270; GO:0030036; GO:0030054; GO:0030864; GO:0042383; GO:0042995; GO:0045211; GO:0048666; GO:0051015; GO:0055001; GO:0090257; GO:0120025 40788 XM_044310373.1 0 3 0 8 2 NA NA NA NA NA NA 40789 XM_044318779.1 349 638 458 1103 788 NA NA NA NA NA NA 40790 XM_044317958.1 125 82 71 91 232 NA NA NA NA NA NA 40791 XM_044314109.1 40 0 0 0 0 Q9NX74 1.21e-160 tRNA-dihydrouridine(20) synthase [NAD(P)+]-like (EC 1.3.1.91) (Dihydrouridine synthase 2) (Up-regulated in lung cancer protein 8) (URLC8) (tRNA-dihydrouridine synthase 2-like) (hDUS2) Homo sapiens (Human) negative regulation of cell death [GO:0060548]; tRNA dihydrouridine synthesis [GO:0002943] GO:0000049; GO:0002943; GO:0003725; GO:0004860; GO:0005737; GO:0005783; GO:0005829; GO:0010181; GO:0017150; GO:0050660; GO:0060548; GO:0070402; GO:0102264 40792 XM_029328943.2 68 0 8 35 72 Q921H9 5.37e-38 Cytochrome c oxidase assembly factor 7 (Beta-lactamase hcp-like protein) (Respiratory chain assembly factor 1) (Sel1 repeat-containing protein 1) Mus musculus (Mouse) NA GO:0005654; GO:0005739; GO:0005758 40793 XM_044316316.1 12 0 30 50 35 NA NA NA NA NA NA 40794 XM_044313786.1 251 172 83 196 120 NA NA NA NA NA NA 40795 XM_044308703.1 16 164 198 0 87 NA NA NA NA NA NA 40796 XR_003827000.1 0 0 3 0 11 NA NA NA NA NA NA 40797 XM_044325951.1 0 0 0 88 128 NA NA NA NA NA NA 40798 XM_029335643.2 0 103 0 0 0 P31422 0 Metabotropic glutamate receptor 3 (mGluR3) Rattus norvegicus (Rat) G protein-coupled glutamate receptor signaling pathway [GO:0007216]; gene expression [GO:0010467]; modulation of chemical synaptic transmission [GO:0050804]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; regulation of synaptic transmission, glutamatergic [GO:0051966]; sensory perception of pain [GO:0019233] GO:0001640; GO:0001641; GO:0005246; GO:0005886; GO:0007216; GO:0010467; GO:0014069; GO:0019233; GO:0030424; GO:0042734; GO:0043005; GO:0043197; GO:0045211; GO:0050804; GO:0051966; GO:0097110; GO:0097449; GO:0098794; GO:0098978; GO:0099170 40799 XM_029357588.2 1710 936 952 1669 1879 Q8TD57 0 Dynein axonemal heavy chain 3 (Axonemal beta dynein heavy chain 3) (HsADHC3) (Ciliary dynein heavy chain 3) (Dnahc3-b) Homo sapiens (Human) cilium-dependent cell motility [GO:0060285]; microtubule-based movement [GO:0007018] GO:0003777; GO:0005524; GO:0005858; GO:0005874; GO:0007018; GO:0008569; GO:0030286; GO:0045505; GO:0051959; GO:0060285; GO:0097729 40800 XM_044327958.1 0 1 0 0 34 NA NA NA NA NA NA 40801 XR_006392203.1 62 153 62 67 76 NA NA NA NA NA NA 40802 XM_029333291.2 1975 1600 1314 1729 1991 Q14186 4.84e-120 Transcription factor Dp-1 (DRTF1-polypeptide 1) (DRTF1) (E2F dimerization partner 1) Homo sapiens (Human) anoikis [GO:0043276]; epidermis development [GO:0008544]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of fat cell proliferation [GO:0070345]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA biosynthetic process [GO:2000278]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; transcription by RNA polymerase II [GO:0006366] GO:0000083; GO:0000785; GO:0000981; GO:0000987; GO:0003700; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006357; GO:0006366; GO:0008544; GO:0019904; GO:0035189; GO:0043276; GO:0043433; GO:0045944; GO:0051091; GO:0070345; GO:0090575; GO:0140297; GO:1900087; GO:2000278 40803 XM_044313903.1 0 175 285 145 0 P35546 2.8e-88 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; anatomical structure morphogenesis [GO:0009653]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006919; GO:0007156; GO:0007158; GO:0007169; GO:0007399; GO:0009410; GO:0009653; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030182; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0098797; GO:2001241 40804 XM_044317561.1 36 0 43 15 16 Q99315 1.93e-26 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 40805 XM_029342487.2 256 21 98 565 85 NA NA NA NA NA NA 40806 XM_044315948.1 18 21 38 1 102 NA NA NA NA NA NA 40807 XM_029324189.2 10 0 0 4 10 NA NA NA NA NA NA 40808 XM_029337236.2 48 44 65 9 25 P62246 8.89e-80 40S ribosomal protein S15a Rattus norvegicus (Rat) positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; response to virus [GO:0009615]; translation [GO:0006412] GO:0003735; GO:0005737; GO:0006412; GO:0008284; GO:0009615; GO:0022626; GO:0022627; GO:0045202; GO:0045787 40809 XR_006391709.1 24 71 21 24 29 NA NA NA NA NA NA 40810 XM_029340703.2 594 297 367 162 468 A0JN62 0 Centrosomal protein of 120 kDa (Cep120) (Coiled-coil domain-containing protein 100) Bos taurus (Bovine) astral microtubule organization [GO:0030953]; centrosome cycle [GO:0007098]; cerebral cortex development [GO:0021987]; interkinetic nuclear migration [GO:0022027]; neurogenesis [GO:0022008]; positive regulation of centriole elongation [GO:1903724]; positive regulation of centrosome duplication [GO:0010825]; positive regulation of cilium assembly [GO:0045724]; positive regulation of establishment of protein localization [GO:1904951] GO:0005737; GO:0005813; GO:0005814; GO:0007098; GO:0008022; GO:0010825; GO:0021987; GO:0022008; GO:0022027; GO:0030953; GO:0045724; GO:1903724; GO:1904951 40811 XM_029351374.2 2 62 36 12 42 NA NA NA NA NA NA 40812 XR_006392021.1 74 9 21 85 28 Q5UPX0 7.86e-30 Putative ATP-dependent RNA helicase R290 (EC 3.6.4.13) Acanthamoeba polyphaga mimivirus (APMV) DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260] GO:0003676; GO:0003724; GO:0005524; GO:0006260; GO:0006281; GO:0006310; GO:0016887; GO:0043138 40813 XM_029337006.2 14 20 14 18 42 P35406 7.93e-21 D(1) dopamine receptor (Dopamine D1 receptor) Carassius auratus (Goldfish) regulation of biological quality [GO:0065008] GO:0004930; GO:0005886; GO:0065008 40814 XR_006392529.1 0 0 16 0 7 NA NA NA NA NA NA 40815 XM_044312058.1 46 7 0 14 0 NA NA NA NA NA NA 40816 XR_006396836.1 0 27 49 7 13 NA NA NA NA NA NA 40817 XR_006393795.1 2 1 12 2 23 NA NA NA NA NA NA 40818 XM_029330286.2 1224 902 609 1365 1157 O70589 0 Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase) Mus musculus (Mouse) calcium ion import [GO:0070509]; establishment of localization in cell [GO:0051649]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cellular response to growth factor stimulus [GO:0090288]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of wound healing [GO:0061045]; positive regulation of calcium ion import [GO:0090280]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; protein phosphorylation [GO:0006468]; regulation of neurotransmitter secretion [GO:0046928]; regulation of synaptic vesicle exocytosis [GO:2000300]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0001953; GO:0004674; GO:0005080; GO:0005102; GO:0005516; GO:0005524; GO:0005604; GO:0005634; GO:0005652; GO:0005730; GO:0005737; GO:0005829; GO:0005886; GO:0005911; GO:0006357; GO:0006468; GO:0008022; GO:0010839; GO:0014069; GO:0016020; GO:0016323; GO:0016363; GO:0030165; GO:0030425; GO:0031982; GO:0032024; GO:0032991; GO:0042043; GO:0042734; GO:0043025; GO:0044877; GO:0045121; GO:0045202; GO:0045944; GO:0046928; GO:0048471; GO:0051649; GO:0060170; GO:0061003; GO:0061045; GO:0070509; GO:0072659; GO:0090280; GO:0090288; GO:0097060; GO:0097440; GO:0098685; GO:0098846; GO:0106310; GO:2000300 40819 XM_044317020.1 0 0 0 9 0 P36544 2.45e-85 Neuronal acetylcholine receptor subunit alpha-7 Homo sapiens (Human) acetylcholine receptor signaling pathway [GO:0095500]; calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; cognition [GO:0050890]; dendrite arborization [GO:0140059]; dendritic spine organization [GO:0097061]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; learning or memory [GO:0007611]; membrane depolarization [GO:0051899]; memory [GO:0007613]; modulation of excitatory postsynaptic potential [GO:0098815]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of tumor necrosis factor production [GO:0032720]; nervous system process [GO:0050877]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of CoA-transferase activity [GO:1905920]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; regulation of amyloid fibril formation [GO:1905906]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of membrane potential [GO:0042391]; regulation of neuron death [GO:1901214]; regulation of nitric oxide metabolic process [GO:0080164]; response to acetylcholine [GO:1905144]; response to amyloid-beta [GO:1904645]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; sensory processing [GO:0050893]; short-term memory [GO:0007614]; signal transduction [GO:0007165]; synapse organization [GO:0050808]; synaptic transmission, cholinergic [GO:0007271] GO:0001540; GO:0001666; GO:0001934; GO:0005216; GO:0005231; GO:0005262; GO:0005886; GO:0005892; GO:0006811; GO:0006816; GO:0006874; GO:0007165; GO:0007268; GO:0007271; GO:0007611; GO:0007613; GO:0007614; GO:0008284; GO:0015464; GO:0015643; GO:0016020; GO:0017081; GO:0022848; GO:0030594; GO:0032720; GO:0034220; GO:0035094; GO:0042166; GO:0042391; GO:0042803; GO:0043005; GO:0043410; GO:0044853; GO:0045202; GO:0045211; GO:0045766; GO:0050808; GO:0050877; GO:0050890; GO:0050893; GO:0051247; GO:0051899; GO:0070374; GO:0080164; GO:0095500; GO:0097061; GO:0098794; GO:0098815; GO:0140059; GO:1900273; GO:1901214; GO:1902004; GO:1902430; GO:1902991; GO:1904315; GO:1904645; GO:1905144; GO:1905906; GO:1905920; GO:2000463 40820 XM_044310804.1 58 16 3 9 73 Q96AY4 4.36e-168 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 40821 XM_044310804.1 58 16 3 9 73 Q96AY4 1.69e-146 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 40822 XM_044310804.1 58 16 3 9 73 Q96AY4 5.4e-137 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 40823 XM_044310804.1 58 16 3 9 73 Q96AY4 4.1e-123 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 40824 XM_044310804.1 58 16 3 9 73 Q96AY4 2.23e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 40825 XM_029345697.2 36 15 73 56 98 Q9GZV8 9.15e-127 PR domain zinc finger protein 14 (EC 2.1.1.-) (PR domain-containing protein 14) Homo sapiens (Human) cell fate specification [GO:0001708]; cell morphogenesis [GO:0000902]; embryo implantation [GO:0007566]; fertilization [GO:0009566]; fibroblast growth factor receptor signaling pathway [GO:0008543]; germ cell development [GO:0007281]; germ-line stem cell population maintenance [GO:0030718]; histone H3-R26 methylation [GO:0034972]; homeostasis of number of cells within a tissue [GO:0048873]; inactivation of paternal X chromosome [GO:0060817]; inner cell mass cell fate commitment [GO:0001827]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of flagellated sperm motility [GO:1902093]; positive regulation of stem cell population maintenance [GO:1902459]; regulation of DNA methylation [GO:0044030]; regulation of gene expression [GO:0010468]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000902; GO:0000977; GO:0001708; GO:0001827; GO:0003723; GO:0005634; GO:0005654; GO:0006357; GO:0007281; GO:0007566; GO:0008168; GO:0008543; GO:0009566; GO:0010468; GO:0030718; GO:0031490; GO:0034972; GO:0040037; GO:0044030; GO:0046872; GO:0048873; GO:0060817; GO:1902093; GO:1902459 40826 XM_044323151.1 0 3 0 0 25 P22897 3.32e-119 Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0001618; GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 40827 XM_044323151.1 0 3 0 0 25 P22897 1.29e-100 Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0001618; GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 40828 XM_044323151.1 0 3 0 0 25 P22897 1.95e-61 Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0001618; GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 40829 XM_044323151.1 0 3 0 0 25 P22897 1.73e-42 Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0001618; GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 40830 XM_044323151.1 0 3 0 0 25 P22897 1.99e-40 Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0001618; GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 40831 XM_044323151.1 0 3 0 0 25 P22897 1.24e-37 Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0001618; GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 40832 XM_044323151.1 0 3 0 0 25 P22897 6.23e-34 Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0001618; GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 40833 XM_044323151.1 0 3 0 0 25 P22897 9.3e-33 Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0001618; GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 40834 XM_044323151.1 0 3 0 0 25 P22897 1.74e-21 Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) Homo sapiens (Human) cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; receptor-mediated endocytosis [GO:0006898] GO:0001618; GO:0004888; GO:0005537; GO:0005886; GO:0006898; GO:0009986; GO:0010008; GO:0038023; GO:0038024; GO:0071222; GO:0071346; GO:0071353 40835 XM_029330354.2 2737 1612 1560 1961 1596 Q6DGL7 8.69e-93 BOS complex subunit TMEM147 (Transmembrane protein 147) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005789; GO:0005886; GO:0043022 40836 XM_029332483.2 10 90 12 58 27 NA NA NA NA NA NA 40837 XM_029353235.2 78 61 51 94 57 Q99NI4 1.79e-28 Inositol polyphosphate multikinase (EC 2.7.1.140) (EC 2.7.1.151) (EC 2.7.1.153) (Inositol 1,3,4,6-tetrakisphosphate 5-kinase) Rattus norvegicus (Rat) inositol phosphate biosynthetic process [GO:0032958]; inositol trisphosphate metabolic process [GO:0032957]; necroptotic process [GO:0070266]; neural tube formation [GO:0001841]; phosphorylation [GO:0016310] GO:0000823; GO:0000824; GO:0000825; GO:0001841; GO:0005524; GO:0005634; GO:0005737; GO:0008440; GO:0016301; GO:0016310; GO:0032957; GO:0032958; GO:0046872; GO:0046934; GO:0047326; GO:0051765; GO:0052812; GO:0070266; GO:0097243; GO:0102732 40838 XM_029336268.2 21 10 10 34 53 NA NA NA NA NA NA 40839 XM_044320694.1 525 308 472 350 382 P0C5H0 5.31e-54 Glyoxalase domain-containing protein 5 Canis lupus familiaris (Dog) (Canis familiaris) NA NA 40840 XR_003822787.2 102 28 74 152 103 NA NA NA NA NA NA 40841 XM_029343781.2 2730 1448 2222 5050 3647 NA NA NA NA NA NA 40842 XM_029354377.2 144 39 77 48 190 Q91175 3.06e-42 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (MAR1) Oryzias latipes (Japanese rice fish) (Japanese killifish) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of vasoconstriction [GO:0045907] GO:0001996; GO:0004930; GO:0004937; GO:0005886; GO:0007200; GO:0007204; GO:0007267; GO:0043410; GO:0045907; GO:0071880 40843 XM_044310803.1 0 0 0 4 12 NA NA NA NA NA NA 40844 XR_006394380.1 300 1017 661 224 436 P47990 0 Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase) (XOR)] Gallus gallus (Chicken) urate biosynthetic process [GO:0034418]; xanthine catabolic process [GO:0009115] GO:0004854; GO:0004855; GO:0005506; GO:0005615; GO:0005777; GO:0005829; GO:0009115; GO:0016491; GO:0030151; GO:0034418; GO:0043546; GO:0050660; GO:0051537; GO:0070674; GO:0071949 40845 XR_006394380.1 300 1017 661 224 436 P47990 1.61e-81 Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase) (XOR)] Gallus gallus (Chicken) urate biosynthetic process [GO:0034418]; xanthine catabolic process [GO:0009115] GO:0004854; GO:0004855; GO:0005506; GO:0005615; GO:0005777; GO:0005829; GO:0009115; GO:0016491; GO:0030151; GO:0034418; GO:0043546; GO:0050660; GO:0051537; GO:0070674; GO:0071949 40846 XM_044329184.1 30 23 10 1 105 Q5RCY5 8.19e-70 Protein asteroid homolog 1 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0004518 40847 XM_029349702.2 16 146 16 20 27 NA NA NA NA NA NA 40848 XM_044314956.1 0 0 6 15 1 NA NA NA NA NA NA 40849 XM_044316180.1 488 235 344 367 788 NA NA NA NA NA NA 40850 XM_044308607.1 39 7 7 3 50 NA NA NA NA NA NA 40851 XM_044311806.1 71 19 53 84 52 Q7RTR2 2.28e-39 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 40852 XM_044311806.1 71 19 53 84 52 Q7RTR2 1.11e-37 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 40853 XM_044311806.1 71 19 53 84 52 Q7RTR2 1.93e-36 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 40854 XM_044311806.1 71 19 53 84 52 Q7RTR2 2.16e-35 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 40855 XM_044311806.1 71 19 53 84 52 Q7RTR2 2.34e-35 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 40856 XM_044311806.1 71 19 53 84 52 Q7RTR2 3.01e-31 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 40857 XM_029344037.2 51 0 170 11 91 NA NA NA NA NA NA 40858 XR_006396391.1 864 799 431 792 400 NA NA NA NA NA NA 40859 XM_029327684.2 0 32 0 41 301 NA NA NA NA NA NA 40860 XM_044316787.1 3 19 0 0 0 P05689 5.57e-132 Cathepsin Z (EC 3.4.18.1) Bos taurus (Bovine) proteolysis involved in protein catabolic process [GO:0051603] GO:0004197; GO:0005615; GO:0005764; GO:0051603 40861 XM_044324947.1 482 460 334 594 901 Q15637 4.46e-122 Splicing factor 1 (Mammalian branch point-binding protein) (BBP) (mBBP) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Zinc finger protein 162) Homo sapiens (Human) Leydig cell differentiation [GO:0033327]; male sex determination [GO:0030238]; mRNA 3'-splice site recognition [GO:0000389]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of smooth muscle cell proliferation [GO:0048662]; nuclear body organization [GO:0030575]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of steroid biosynthetic process [GO:0050810]; spliceosomal complex assembly [GO:0000245] GO:0000245; GO:0000389; GO:0000398; GO:0003714; GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0005681; GO:0005840; GO:0008270; GO:0016604; GO:0030238; GO:0030575; GO:0033327; GO:0042802; GO:0048024; GO:0048662; GO:0050810; GO:0089701 40862 XM_044316124.1 0 16 2 0 0 NA NA NA NA NA NA 40863 XR_006397554.1 31 17 34 68 69 NA NA NA NA NA NA 40864 XM_029330322.2 2718 2725 1957 2334 2623 Q9BRN9 6.76e-48 TM2 domain-containing protein 3 (Beta-amyloid-binding protein-like protein 2) (BBP-like protein 2) Homo sapiens (Human) lateral inhibition [GO:0046331]; positive regulation of Notch signaling pathway [GO:0045747] GO:0005886; GO:0045747; GO:0046331 40865 XM_029336505.2 245 169 59 187 139 NA NA NA NA NA NA 40866 XM_044318941.1 6 0 0 11 54 Q58A42 4.93e-73 Protein DD3-3 Dictyostelium discoideum (Social amoeba) NA GO:0016020 40867 XM_029349395.2 97 150 37 352 157 P02752 1.04e-50 Riboflavin-binding protein (RBP) [Cleaved into: Riboflavin-binding protein, plasma form; Riboflavin-binding protein, yolk major form; Riboflavin-binding protein, yolk minor form] Gallus gallus (Chicken) negative regulation of sensory perception of bitter taste [GO:1904661]; negative regulation of sensory perception of sweet taste [GO:1904657]; riboflavin transport [GO:0032218] GO:0009897; GO:0032217; GO:0032218; GO:0038023; GO:1902444; GO:1904657; GO:1904661 40868 XM_029344684.2 210 342 73 159 76 NA NA NA NA NA NA 40869 XM_029341886.2 114 77 33 117 66 F1MBP6 4.61e-75 Kelch-like protein 3 Bos taurus (Bovine) distal tubule morphogenesis [GO:0072156]; gene expression [GO:0010467]; ion homeostasis [GO:0050801]; potassium ion homeostasis [GO:0055075]; protein K48-linked ubiquitination [GO:0070936]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; renal sodium ion absorption [GO:0070294]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0003779; GO:0005829; GO:0005856; GO:0006468; GO:0006511; GO:0010467; GO:0016567; GO:0031463; GO:0050801; GO:0055075; GO:0070294; GO:0070936; GO:0072156; GO:0097602 40870 XM_044317897.1 455 851 183 1736 464 B3EX00 5.52e-157 Uncharacterized skeletal organic matrix protein 1 (Uncharacterized SOMP-1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 40871 XM_029340752.2 1289 1964 1092 980 612 Q96PE7 1.71e-68 Methylmalonyl-CoA epimerase, mitochondrial (EC 5.1.99.1) (DL-methylmalonyl-CoA racemase) Homo sapiens (Human) L-methylmalonyl-CoA metabolic process [GO:0046491]; short-chain fatty acid catabolic process [GO:0019626] GO:0004493; GO:0005759; GO:0019626; GO:0046491; GO:0046872 40872 XM_044319537.1 112 79 63 142 152 Q76KP1 4.29e-55 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Homo sapiens (Human) NA GO:0008376; GO:0032580; GO:0033842 40873 XM_044319537.1 112 79 63 142 152 Q76KP1 1.4e-22 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Homo sapiens (Human) NA GO:0008376; GO:0032580; GO:0033842 40874 XM_044313708.1 20 51 76 143 111 NA NA NA NA NA NA 40875 XM_029333627.2 19 8 4 7 25 NA NA NA NA NA NA 40876 XM_029344520.2 356 277 306 235 336 NA NA NA NA NA NA 40877 XM_044318604.1 362 411 216 630 135 A0A0G2JDV3 1.13e-31 Guanylate-binding protein 6 (EC 3.6.5.-) (GTP-binding protein 6) (GBP-6) (Guanine nucleotide-binding protein 6) (Macrophage activation 2 like protein) Mus musculus (Mouse) adhesion of symbiont to host [GO:0044406]; cellular response to interferon-beta [GO:0035458]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; defense response to Gram-positive bacterium [GO:0050830]; defense response to protozoan [GO:0042832]; response to bacterium [GO:0009617] GO:0003924; GO:0005525; GO:0009617; GO:0020005; GO:0031410; GO:0035458; GO:0042832; GO:0044406; GO:0050830; GO:0071222; GO:0071346 40878 XM_029332862.2 310 72 148 49 287 NA NA NA NA NA NA 40879 XR_006394387.1 1 0 10 144 25 NA NA NA NA NA NA 40880 XM_029346950.2 249 111 60 304 115 NA NA NA NA NA NA 40881 XM_044320431.1 18 0 132 0 216 NA NA NA NA NA NA 40882 XM_044321038.1 0 0 5 0 11 NA NA NA NA NA NA 40883 XM_029340125.2 99 137 44 440 365 Q9WUJ8 6.18e-38 Origin recognition complex subunit 6 Mus musculus (Mouse) DNA replication initiation [GO:0006270]; DNA-templated DNA replication [GO:0006261]; negative regulation of cell division [GO:0051782] GO:0000808; GO:0001650; GO:0003677; GO:0005654; GO:0005664; GO:0006261; GO:0006270; GO:0051782 40884 XM_029339854.2 473 291 273 301 102 O08795 3.32e-22 Glucosidase 2 subunit beta (80K-H protein) (Glucosidase II subunit beta) (Protein kinase C substrate 60.1 kDa protein heavy chain) (PKCSH) Mus musculus (Mouse) in utero embryonic development [GO:0001701]; liver development [GO:0001889]; N-glycan processing [GO:0006491]; negative regulation of neuron projection development [GO:0010977]; nitrogen compound metabolic process [GO:0006807] GO:0001701; GO:0001889; GO:0003723; GO:0005080; GO:0005509; GO:0005783; GO:0006491; GO:0006807; GO:0010977; GO:0017177; GO:0043231; GO:0044325; GO:0044877; GO:0051219 40885 XM_029344500.2 27 40 20 18 60 NA NA NA NA NA NA 40886 XM_029336736.2 157 47 108 120 268 Q9UKP5 0 A disintegrin and metalloproteinase with thrombospondin motifs 6 (ADAM-TS 6) (ADAM-TS6) (ADAMTS-6) (EC 3.4.24.-) Homo sapiens (Human) aorta development [GO:0035904]; cardiac septum development [GO:0003279]; coronary vasculature development [GO:0060976]; extracellular matrix organization [GO:0030198]; kidney development [GO:0001822]; proteolysis [GO:0006508] GO:0001822; GO:0003279; GO:0004222; GO:0005576; GO:0006508; GO:0008237; GO:0030198; GO:0031012; GO:0035904; GO:0046872; GO:0060976 40887 XM_044317288.1 135 141 102 191 191 Q9Y394 6.12e-74 Dehydrogenase/reductase SDR family member 7 (EC 1.1.1.-) (Retinal short-chain dehydrogenase/reductase 4) (retSDR4) (Short chain dehydrogenase/reductase family 34C member 1) (Protein SDR34C1) Homo sapiens (Human) NA GO:0004090; GO:0005789; GO:0016020; GO:0016616; GO:0052650 40888 XM_044321298.1 0 132 184 63 215 Q13416 1.7e-112 Origin recognition complex subunit 2 Homo sapiens (Human) DNA replication initiation [GO:0006270]; negative regulation of transcription by RNA polymerase II [GO:0000122] GO:0000122; GO:0000781; GO:0000792; GO:0000808; GO:0000939; GO:0003688; GO:0005634; GO:0005654; GO:0005664; GO:0005813; GO:0006270; GO:0016020 40889 XR_006395485.1 106 55 108 146 259 NA NA NA NA NA NA 40890 XM_044325299.1 54 35 18 32 36 P10394 1.6e-32 Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 40891 XR_006395086.1 8 37 12 0 3 NA NA NA NA NA NA 40892 XM_044316988.1 235 154 106 225 209 A1L1W9 9.11e-28 Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10) Danio rerio (Zebrafish) (Brachydanio rerio) aromatic amino acid transport [GO:0015801]; thyroid hormone transport [GO:0070327] GO:0005302; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0070327 40893 XM_029358117.2 94 31 42 73 80 Q92752 5.98e-59 Tenascin-R (TN-R) (Janusin) (Restrictin) Homo sapiens (Human) associative learning [GO:0008306]; axon extension involved in regeneration [GO:0048677]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198]; locomotory exploration behavior [GO:0035641]; long-term synaptic potentiation [GO:0060291]; negative regulation of axon extension involved in regeneration [GO:0048692]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of neuron projection development [GO:0010977]; negative regulation of synaptic transmission [GO:0050805]; neuroblast migration [GO:0097402]; neuromuscular process controlling balance [GO:0050885]; neuron cell-cell adhesion [GO:0007158]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transmission of nerve impulse [GO:0051971]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of cell migration [GO:0030334]; synapse organization [GO:0050808]; synaptic transmission, glutamatergic [GO:0035249]; telencephalon cell migration [GO:0022029] GO:0005102; GO:0005576; GO:0005615; GO:0007155; GO:0007158; GO:0007411; GO:0008306; GO:0009986; GO:0010977; GO:0022029; GO:0022408; GO:0030155; GO:0030198; GO:0030334; GO:0035249; GO:0035641; GO:0045121; GO:0045595; GO:0048677; GO:0048692; GO:0050805; GO:0050808; GO:0050885; GO:0051968; GO:0051971; GO:0060291; GO:0062023; GO:0072534; GO:0090733; GO:0097402; GO:0098685; GO:0098978 40894 XM_029334162.2 47 0 185 154 249 Q8IUH5 0 Palmitoyltransferase ZDHHC17 (EC 2.3.1.225) (Acyltransferase ZDHHC17) (EC 2.3.1.-) (DHHC domain-containing cysteine-rich protein 17) (DHHC17) (Huntingtin yeast partner H) (Huntingtin-interacting protein 14) (HIP-14) (Huntingtin-interacting protein 3) (HIP-3) (Huntingtin-interacting protein H) (Putative MAPK-activating protein PM11) (Putative NF-kappa-B-activating protein 205) (Zinc finger DHHC domain-containing protein 17) Homo sapiens (Human) axonogenesis [GO:0007409]; lipoprotein transport [GO:0042953]; peptidyl-L-cysteine S-palmitoylation [GO:0018230]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein palmitoylation [GO:0018345]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of neurotrophin TRK receptor signaling pathway [GO:0051386] GO:0000139; GO:0005102; GO:0005794; GO:0007409; GO:0016235; GO:0016409; GO:0018230; GO:0018345; GO:0019705; GO:0019706; GO:0030660; GO:0042734; GO:0042802; GO:0042953; GO:0042995; GO:0043123; GO:0043231; GO:0051386; GO:0070372; GO:0140439 40895 XM_029357563.2 480 481 763 288 430 NA NA NA NA NA NA 40896 XM_044309826.1 5 37 23 3 108 NA NA NA NA NA NA 40897 XM_044328623.1 570 736 202 224 283 Q9NZS9 7.45e-68 Bifunctional apoptosis regulator (RING finger protein 47) Homo sapiens (Human) apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000209; GO:0005783; GO:0005789; GO:0005886; GO:0006511; GO:0006915; GO:0016020; GO:0030674; GO:0043066; GO:0043161; GO:0046872; GO:0051865; GO:0061630; GO:0070534; GO:0070936; GO:0089720; GO:1903895 40898 XM_044311135.1 0 0 0 6 0 NA NA NA NA NA NA 40899 XM_044326403.1 0 0 22 0 50 P30975 2.6e-24 Tachykinin-like peptides receptor 99D (Tachykinin-like receptor at 99D) (dTKR) Drosophila melanogaster (Fruit fly) detection of chemical stimulus involved in sensory perception of smell [GO:0050911]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; neuropeptide signaling pathway [GO:0007218]; olfactory behavior [GO:0042048]; positive regulation of sensory perception of pain [GO:1904058]; tachykinin receptor signaling pathway [GO:0007217] GO:0004995; GO:0005886; GO:0007186; GO:0007217; GO:0007218; GO:0008188; GO:0016020; GO:0042048; GO:0050805; GO:0050911; GO:1904058 40900 XR_006392629.1 36 30 5 70 27 NA NA NA NA NA NA 40901 XM_044312718.1 17 28 8 33 7 F1R8P4 1.4e-79 Glycine receptor subunit alpha-2 Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0004888; GO:0005254; GO:0016594; GO:0016933; GO:0022824; GO:0034707; GO:0042995; GO:0045211; GO:0046872 40902 XM_029350433.2 18497 9754 6931 9831 7219 P40123 4.2e-126 Adenylyl cyclase-associated protein 2 (CAP 2) Homo sapiens (Human) activation of adenylate cyclase activity [GO:0007190]; cAMP-mediated signaling [GO:0019933]; cell morphogenesis [GO:0000902]; establishment or maintenance of cell polarity [GO:0007163]; presynaptic actin cytoskeleton organization [GO:0099140]; regulation of adenylate cyclase activity [GO:0045761]; signal transduction [GO:0007165] GO:0000902; GO:0003779; GO:0005737; GO:0005886; GO:0007163; GO:0007165; GO:0007190; GO:0008179; GO:0014069; GO:0019933; GO:0042802; GO:0045761; GO:0099140 40903 XR_003826366.2 64 70 107 71 206 NA NA NA NA NA NA 40904 XM_044321307.1 42 130 60 52 0 Q13416 6.26e-113 Origin recognition complex subunit 2 Homo sapiens (Human) DNA replication initiation [GO:0006270]; negative regulation of transcription by RNA polymerase II [GO:0000122] GO:0000122; GO:0000781; GO:0000792; GO:0000808; GO:0000939; GO:0003688; GO:0005634; GO:0005654; GO:0005664; GO:0005813; GO:0006270; GO:0016020 40905 XM_044321480.1 4 28 14 41 8 NA NA NA NA NA NA 40906 XM_029352108.2 397 290 349 321 296 P55878 2.29e-84 Zinc finger protein GLI1 (GLI) Gallus gallus (Chicken) cell differentiation [GO:0030154]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; smoothened signaling pathway [GO:0007224] GO:0000978; GO:0000981; GO:0003682; GO:0005634; GO:0005737; GO:0006357; GO:0007224; GO:0010628; GO:0030154; GO:0043565; GO:0045893; GO:0045944; GO:0046872 40907 XM_044308011.1 108 37 0 573 538 NA NA NA NA NA NA 40908 XM_044311054.1 77 79 80 104 48 P16157 3.87e-85 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 40909 XM_044311054.1 77 79 80 104 48 P16157 1.76e-76 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 40910 XM_044311054.1 77 79 80 104 48 P16157 6.05e-74 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 40911 XM_044311054.1 77 79 80 104 48 P16157 2.72e-71 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 40912 XM_044311054.1 77 79 80 104 48 P16157 2.93e-68 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 40913 XM_044311054.1 77 79 80 104 48 P16157 5.46e-64 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 40914 XM_029347179.2 33 22 17 23 41 NA NA NA NA NA NA 40915 XM_029351563.2 15 7 3 20 9 NA NA NA NA NA NA 40916 XM_044322138.1 643 413 296 358 295 Q9ET47 2.58e-67 Espin (Ectoplasmic specialization protein) Mus musculus (Mouse) actin filament bundle assembly [GO:0051017]; actin filament network formation [GO:0051639]; locomotory behavior [GO:0007626]; microvillar actin bundle assembly [GO:0030034]; negative regulation of cytoskeleton organization [GO:0051494]; parallel actin filament bundle assembly [GO:0030046]; positive regulation of filopodium assembly [GO:0051491]; sensory perception of sound [GO:0007605] GO:0005737; GO:0005829; GO:0005902; GO:0005903; GO:0007605; GO:0007626; GO:0015629; GO:0017124; GO:0030034; GO:0030046; GO:0031941; GO:0032420; GO:0032421; GO:0032426; GO:0043197; GO:0051015; GO:0051017; GO:0051491; GO:0051494; GO:0051639; GO:0070161 40917 XM_044318895.1 487 98 285 863 823 NA NA NA NA NA NA 40918 XM_029352304.2 4613 5544 2391 3844 3983 NA NA NA NA NA NA 40919 XM_029335916.2 7371 4361 5821 4493 3990 Q8K4R4 9.11e-122 Cytoplasmic phosphatidylinositol transfer protein 1 (Mammalian rdgB homolog beta) (M-rdgB beta) (MrdgBbeta) (mM-rdgBbeta) (Retinal degeneration B homolog beta) (RdgBbeta) Mus musculus (Mouse) phosphatidylinositol metabolic process [GO:0046488]; phospholipid transport [GO:0015914]; signal transduction [GO:0007165] GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0007165; GO:0008526; GO:0015914; GO:0035091; GO:0046488; GO:0070300; GO:1901611; GO:1990050 40920 XM_029344915.2 0 0 8 7 6 NA NA NA NA NA NA 40921 XM_044329200.1 264 139 177 214 526 NA NA NA NA NA NA 40922 XM_044314723.1 210 287 215 120 197 Q91VS8 5.5e-154 FERM, ARHGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR) (FERM, RhoGEF and pleckstrin domain-containing protein 2) Mus musculus (Mouse) actin cytoskeleton reorganization [GO:0031532]; cell adhesion [GO:0007155]; hair cycle process [GO:0022405]; neuron remodeling [GO:0016322]; osteoclast differentiation [GO:0030316]; podosome assembly [GO:0071800]; Rac protein signal transduction [GO:0016601]; regulation of integrin activation [GO:0033623]; semaphorin-plexin signaling pathway [GO:0071526] GO:0005085; GO:0005737; GO:0005829; GO:0005856; GO:0007155; GO:0008092; GO:0016322; GO:0016601; GO:0022405; GO:0030316; GO:0031532; GO:0033623; GO:0071526; GO:0071800 40923 XM_044314723.1 210 287 215 120 197 Q91VS8 2.73e-37 FERM, ARHGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR) (FERM, RhoGEF and pleckstrin domain-containing protein 2) Mus musculus (Mouse) actin cytoskeleton reorganization [GO:0031532]; cell adhesion [GO:0007155]; hair cycle process [GO:0022405]; neuron remodeling [GO:0016322]; osteoclast differentiation [GO:0030316]; podosome assembly [GO:0071800]; Rac protein signal transduction [GO:0016601]; regulation of integrin activation [GO:0033623]; semaphorin-plexin signaling pathway [GO:0071526] GO:0005085; GO:0005737; GO:0005829; GO:0005856; GO:0007155; GO:0008092; GO:0016322; GO:0016601; GO:0022405; GO:0030316; GO:0031532; GO:0033623; GO:0071526; GO:0071800 40924 XR_006396563.1 88 18 167 26 91 NA NA NA NA NA NA 40925 XM_029356453.2 1180 982 252 1746 2104 Q60544 0 Transcription initiation factor TFIID subunit 1 (EC 2.3.1.48) (EC 2.7.11.1) (Cell cycle gene 1 protein) (TBP-associated factor 250 kDa) (p250) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250) Mesocricetus auratus (Golden hamster) cell cycle [GO:0007049]; phosphorylation [GO:0016310]; positive regulation of transcription by RNA polymerase II [GO:0045944]; transcription initiation at RNA polymerase II promoter [GO:0006367] GO:0001091; GO:0003677; GO:0004402; GO:0004674; GO:0005524; GO:0005669; GO:0006367; GO:0007049; GO:0016251; GO:0016310; GO:0017025; GO:0045944; GO:0071339; GO:0106310 40926 XM_044322876.1 0 0 0 16 0 D4AD75 0 NA NA NA NA 40927 XM_044326537.1 22 7 0 12 13 Q9UHC3 1.87e-50 Acid-sensing ion channel 3 (ASIC3) (hASIC3) (Amiloride-sensitive cation channel 3) (Neuronal amiloride-sensitive cation channel 3) (Testis sodium channel 1) (hTNaC1) Homo sapiens (Human) detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; sensory perception [GO:0007600]; sensory perception of sour taste [GO:0050915]; signal transduction [GO:0007165]; sodium ion transmembrane transport [GO:0035725] GO:0005261; GO:0005272; GO:0005886; GO:0007165; GO:0007600; GO:0009408; GO:0010447; GO:0015280; GO:0035725; GO:0042931; GO:0044736; GO:0048471; GO:0050915; GO:0050965; GO:0050966; GO:0050968 40928 XM_029348731.2 0 0 27 0 9 B0UY98 2.41e-22 NA NA NA NA 40929 XM_044324147.1 704 645 493 678 730 A1L1W9 2.3e-71 Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10) Danio rerio (Zebrafish) (Brachydanio rerio) aromatic amino acid transport [GO:0015801]; thyroid hormone transport [GO:0070327] GO:0005302; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0070327 40930 XM_044324147.1 704 645 493 678 730 A1L1W9 1.98e-68 Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10) Danio rerio (Zebrafish) (Brachydanio rerio) aromatic amino acid transport [GO:0015801]; thyroid hormone transport [GO:0070327] GO:0005302; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0070327 40931 XM_044324000.1 40 62 17 7 0 NA NA NA NA NA NA 40932 XM_029348756.2 37 39 14 36 62 Q5XGY9 3.25e-68 Meiotic nuclear division protein 1 homolog Xenopus laevis (African clawed frog) reciprocal meiotic recombination [GO:0007131] GO:0003690; GO:0005634; GO:0007131 40933 XM_029323404.2 446 489 399 419 451 NA NA NA NA NA NA 40934 XM_044327576.1 68 0 0 0 0 NA NA NA NA NA NA 40935 XM_044306988.1 0 4 12 1 0 Q96MB7 3.05e-42 Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease) Homo sapiens (Human) NA GO:0004518; GO:0005634; GO:0005829; GO:0005886; GO:0034451; GO:0046872 40936 XM_029335319.2 2082 764 536 1731 1639 Q3US41 6.39e-137 Epithelial splicing regulatory protein 1 (RNA-binding motif protein 35A) (RNA-binding protein 35A) Mus musculus (Mouse) alternative mRNA splicing, via spliceosome [GO:0000380]; branching involved in salivary gland morphogenesis [GO:0060445]; epithelial cell proliferation [GO:0050673]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; positive regulation of epithelial cell proliferation [GO:0050679]; regulation of inner ear auditory receptor cell fate specification [GO:0042669]; regulation of RNA splicing [GO:0043484] GO:0000380; GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0016604; GO:0042669; GO:0043484; GO:0050673; GO:0050679; GO:0060441; GO:0060445; GO:1990904 40937 XM_044313561.1 295 280 283 417 426 O54928 8.13e-56 Suppressor of cytokine signaling 5 (SOCS-5) (Cytokine-inducible SH2-containing protein 5) Mus musculus (Mouse) cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cytokine-mediated signaling pathway [GO:0019221]; epidermal growth factor receptor signaling pathway [GO:0007173]; intracellular signal transduction [GO:0035556]; negative regulation of endothelial cell activation [GO:1904988]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of signal transduction [GO:0009968]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; phosphatidylinositol phosphate biosynthetic process [GO:0046854]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of T-helper 1 cell differentiation [GO:0045627]; protein ubiquitination [GO:0016567]; receptor signaling pathway via JAK-STAT [GO:0007259]; vascular endothelial cell response to fluid shear stress [GO:0097699] GO:0005154; GO:0005737; GO:0005942; GO:0007173; GO:0007175; GO:0007259; GO:0009968; GO:0016567; GO:0019210; GO:0019221; GO:0030971; GO:0032436; GO:0032715; GO:0035556; GO:0045627; GO:0045629; GO:0046854; GO:0046935; GO:0050728; GO:0071404; GO:0071638; GO:0097699; GO:1904988 40938 XM_029336031.2 5436 3378 3159 5791 5639 P26369 2.53e-153 Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor 65 kDa subunit) (U2 snRNP auxiliary factor large subunit) Mus musculus (Mouse) mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of RNA splicing [GO:0033120]; RNA splicing [GO:0008380] GO:0000243; GO:0000398; GO:0000974; GO:0005634; GO:0005681; GO:0008187; GO:0008380; GO:0016607; GO:0019899; GO:0030628; GO:0031397; GO:0033120; GO:0048025; GO:0070742; GO:0071004; GO:0089701; GO:0140678 40939 XM_044327314.1 12 0 16 2 85 NA NA NA NA NA NA 40940 XM_044325068.1 0 2 8 5 55 NA NA NA NA NA NA 40941 XR_006391371.1 0 0 61 0 0 NA NA NA NA NA NA 40942 XM_029342566.2 20 0 0 0 0 Q8R4V5 4.48e-27 Oncoprotein-induced transcript 3 protein (Liver-specific zona pellucida domain-containing protein) Mus musculus (Mouse) urate homeostasis [GO:1903118] GO:0005201; GO:0005509; GO:0005615; GO:0005635; GO:0009986; GO:1903118 40943 XM_029356826.2 18 0 0 8 0 NA NA NA NA NA NA 40944 XM_044327040.1 0 223 169 338 193 NA NA NA NA NA NA 40945 XM_029323719.2 510 242 363 214 632 P25931 4.55e-28 RYamide receptor (Neuropeptide Y-like receptor) (NPY-R) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218] GO:0001653; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0016020 40946 XM_044313204.1 291 163 293 771 406 NA NA NA NA NA NA 40947 XM_029329285.2 572 452 312 482 393 Q1LV46 1.61e-51 Protein ABHD14A (EC 3.-.-.-) (Alpha/beta hydrolase domain-containing protein 14A) (Abhydrolase domain-containing protein 14A) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005737; GO:0016020; GO:0016787 40948 XM_044318847.1 0 3 0 0 31 NA NA NA NA NA NA 40949 XM_029324176.2 431 557 391 284 274 NA NA NA NA NA NA 40950 XR_006392657.1 53 21 69 48 196 P16924 2.38e-107 Prolyl 4-hydroxylase subunit alpha-1 (4-PH alpha-1) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1) Gallus gallus (Chicken) peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401] GO:0004656; GO:0005506; GO:0005783; GO:0005788; GO:0018401; GO:0031418 40951 XM_044315086.1 335 19 54 0 26 NA NA NA NA NA NA 40952 XM_044319782.1 0 10 0 0 0 Q9P2E3 0 NFX1-type zinc finger-containing protein 1 Homo sapiens (Human) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 40953 XM_044319782.1 0 10 0 0 0 Q9P2E3 1.11e-67 NFX1-type zinc finger-containing protein 1 Homo sapiens (Human) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 40954 XM_044313552.1 3 31 0 11 26 Q9QZ08 1.2e-90 N-acetyl-D-glucosamine kinase (N-acetylglucosamine kinase) (EC 2.7.1.59) (GlcNAc kinase) Mus musculus (Mouse) N-acetylglucosamine metabolic process [GO:0006044]; N-acetylneuraminate catabolic process [GO:0019262] GO:0005524; GO:0006044; GO:0009384; GO:0019262; GO:0045127 40955 XR_006392093.1 750 789 289 577 434 NA NA NA NA NA NA 40956 XM_044308742.1 190 152 135 279 356 NA NA NA NA NA NA 40957 XM_044323856.1 77 0 37 3 2 NA NA NA NA NA NA 40958 XM_044317149.1 643 422 293 670 470 NA NA NA NA NA NA 40959 XM_044310278.1 26 3 5 1 23 NA NA NA NA NA NA 40960 XM_044319627.1 0 0 0 97 71 Q9DBQ7 4.49e-69 Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin-binding protein PACE-1) (SCY1-like protein 3) Mus musculus (Mouse) inflammatory response [GO:0006954]; neuron development [GO:0048666]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; spinal cord motor neuron differentiation [GO:0021522] GO:0000139; GO:0004672; GO:0005524; GO:0005737; GO:0005794; GO:0006468; GO:0006954; GO:0008104; GO:0021522; GO:0030027; GO:0042802; GO:0048666 40961 XM_044316367.1 1196 851 577 998 1189 NA NA NA NA NA NA 40962 XR_006395922.1 468 533 380 1960 1896 NA NA NA NA NA NA 40963 XM_044308547.1 0 0 5 7 102 NA NA NA NA NA NA 40964 XM_044319937.1 119 52 0 145 121 Q68DA7 1.12e-69 Formin-1 (Limb deformity protein homolog) Homo sapiens (Human) actin nucleation [GO:0045010]; forelimb morphogenesis [GO:0035136]; gene expression [GO:0010467]; hindlimb morphogenesis [GO:0035137]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of actin nucleation [GO:0051127]; positive regulation of focal adhesion assembly [GO:0051894]; skeletal system morphogenesis [GO:0048705]; ureteric bud invasion [GO:0072092] GO:0003779; GO:0005634; GO:0005737; GO:0005789; GO:0005884; GO:0005886; GO:0005912; GO:0008017; GO:0010467; GO:0017124; GO:0030838; GO:0035136; GO:0035137; GO:0045010; GO:0048705; GO:0051127; GO:0051894; GO:0072092 40965 XM_044328426.1 18 0 0 35 79 NA NA NA NA NA NA 40966 XM_029351429.2 0 0 27 97 0 Q8AXC7 3.97e-60 Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) chemotaxis [GO:0006935] GO:0005018; GO:0005524; GO:0005886; GO:0006935 40967 XM_029323962.2 16 96 11 18 65 NA NA NA NA NA NA 40968 XM_044310227.1 0 1 32 3 0 NA NA NA NA NA NA 40969 XM_044321861.1 0 0 131 321 286 Q8BMK0 9.18e-36 Centrosomal protein of 85 kDa (Cep85) (Coiled-coil domain-containing protein 21) Mus musculus (Mouse) chromosome segregation [GO:0007059]; negative regulation of protein kinase activity [GO:0006469]; neuron migration [GO:0001764]; regulation of mitotic centrosome separation [GO:0046602] GO:0000242; GO:0000922; GO:0001764; GO:0005730; GO:0005794; GO:0005813; GO:0005829; GO:0006469; GO:0007059; GO:0046602 40970 XM_044320182.1 0 19 13 14 22 NA NA NA NA NA NA 40971 XM_029355645.2 0 0 0 0 13 NA NA NA NA NA NA 40972 XR_006396361.1 39 0 2 39 17 NA NA NA NA NA NA 40973 XM_029350392.2 18 14 0 25 0 Q61006 8.82e-77 Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine-protein kinase receptor) (MuSK) (Muscle-specific kinase receptor) Mus musculus (Mouse) cell differentiation [GO:0030154]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; motor neuron apoptotic process [GO:0097049]; negative regulation of gene expression [GO:0010629]; neuromuscular junction development [GO:0007528]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of motor neuron apoptotic process [GO:2000673]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein geranylgeranylation [GO:2000541]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; positive regulation of synaptic assembly at neuromuscular junction [GO:0045887]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; protein autophosphorylation [GO:0046777]; receptor clustering [GO:0043113]; regulation of DNA-templated transcription [GO:0006355]; regulation of synaptic assembly at neuromuscular junction [GO:0008582]; response to electrical stimulus [GO:0051602]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0001934; GO:0004713; GO:0004714; GO:0005518; GO:0005524; GO:0005886; GO:0006355; GO:0007169; GO:0007528; GO:0007613; GO:0008582; GO:0009897; GO:0010628; GO:0010629; GO:0016020; GO:0019901; GO:0030154; GO:0030165; GO:0031594; GO:0032224; GO:0033674; GO:0038062; GO:0042995; GO:0043113; GO:0043235; GO:0045202; GO:0045211; GO:0045887; GO:0046777; GO:0046872; GO:0050731; GO:0051602; GO:0060291; GO:0071340; GO:0097049; GO:1904395; GO:2000541; GO:2000673 40974 XM_029326287.2 39 56 4 11 93 NA NA NA NA NA NA 40975 XM_029356900.2 13 11 4 12 72 NA NA NA NA NA NA 40976 XM_029336033.2 22 131 0 105 81 NA NA NA NA NA NA 40977 XM_029332610.2 5 20 10 9 15 NA NA NA NA NA NA 40978 XR_006396681.1 34 9 4 19 38 NA NA NA NA NA NA 40979 XM_044314997.1 4 10 0 2 21 NA NA NA NA NA NA 40980 XM_029323463.2 26 1 40 3 88 NA NA NA NA NA NA 40981 XM_044323294.1 0 0 0 0 75 Q5R5U3 2.3e-83 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 40982 XM_044323294.1 0 0 0 0 75 Q5R5U3 6.01e-83 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 40983 XM_044323294.1 0 0 0 0 75 Q5R5U3 4.08e-79 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 40984 XM_044323294.1 0 0 0 0 75 Q5R5U3 2.5e-78 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 40985 XM_044323294.1 0 0 0 0 75 Q5R5U3 5.5e-72 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 40986 XM_044323294.1 0 0 0 0 75 Q5R5U3 3.97e-62 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 40987 XM_044323294.1 0 0 0 0 75 Q5R5U3 1.28e-60 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 40988 XM_044321109.1 748 784 438 873 1160 NA NA NA NA NA NA 40989 XR_003828021.2 0 0 3 13 0 NA NA NA NA NA NA 40990 XM_029333431.2 5 17 23 10 147 Q91ZR5 2.38e-27 Cation channel sperm-associated protein 1 (CatSper1) Mus musculus (Mouse) calcium ion transport [GO:0006816]; cell differentiation [GO:0030154]; flagellated sperm motility [GO:0030317]; fusion of sperm to egg plasma membrane involved in single fertilization [GO:0007342]; regulation of calcium ion transport [GO:0051924]; regulation of cilium beat frequency involved in ciliary motility [GO:0060296]; regulation of ion transmembrane transport [GO:0034765]; spermatogenesis [GO:0007283] GO:0005227; GO:0005245; GO:0005886; GO:0006816; GO:0007283; GO:0007342; GO:0030154; GO:0030317; GO:0034765; GO:0036128; GO:0051924; GO:0060296; GO:0097228 40991 XR_006396005.1 54 56 11 28 3 NA NA NA NA NA NA 40992 XM_044308598.1 84 31 45 17 279 NA NA NA NA NA NA 40993 XM_044311311.1 14 1 4 0 8 NA NA NA NA NA NA 40994 XM_029334582.2 0 428 129 0 0 Q9UKP5 8.07e-124 A disintegrin and metalloproteinase with thrombospondin motifs 6 (ADAM-TS 6) (ADAM-TS6) (ADAMTS-6) (EC 3.4.24.-) Homo sapiens (Human) aorta development [GO:0035904]; cardiac septum development [GO:0003279]; coronary vasculature development [GO:0060976]; extracellular matrix organization [GO:0030198]; kidney development [GO:0001822]; proteolysis [GO:0006508] GO:0001822; GO:0003279; GO:0004222; GO:0005576; GO:0006508; GO:0008237; GO:0030198; GO:0031012; GO:0035904; GO:0046872; GO:0060976 40995 XM_044310976.1 14 14 24 1 97 NA NA NA NA NA NA 40996 XM_029358420.2 2612 1409 1287 2321 1809 Q3TLH4 4.02e-24 Protein PRRC2C (BAT2 domain-containing protein 1) (HLA-B-associated transcript 2-like 2) (Proline-rich and coiled-coil-containing protein 2C) Mus musculus (Mouse) cell differentiation [GO:0030154]; hematopoietic progenitor cell differentiation [GO:0002244]; stress granule assembly [GO:0034063] GO:0002244; GO:0005829; GO:0008022; GO:0010494; GO:0030154; GO:0034063 40997 XM_029349147.2 242 186 80 76 38 NA NA NA NA NA NA 40998 XM_044314966.1 4 0 18 0 21 NA NA NA NA NA NA 40999 XM_029328547.2 0 0 89 0 0 Q3TLD5 2.24e-28 Unconventional prefoldin RPB5 interactor (Protein NNX3) (Protein phosphatase 1 regulatory subunit 19) (RNA polymerase II subunit 5-mediating protein) (RPB5-mediating protein) Mus musculus (Mouse) cellular response to growth factor stimulus [GO:0071363]; cellular response to steroid hormone stimulus [GO:0071383]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of phosphatase activity [GO:0010923]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of cell growth [GO:0001558]; regulation of transcription by RNA polymerase II [GO:0006357]; response to virus [GO:0009615] GO:0000122; GO:0000993; GO:0001558; GO:0003682; GO:0003714; GO:0004864; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005829; GO:0006357; GO:0009615; GO:0010923; GO:0019212; GO:0030425; GO:0051219; GO:0071363; GO:0071383; GO:1990062; GO:2001243 41000 XR_006395202.1 0 0 0 9 0 NA NA NA NA NA NA 41001 XM_029342238.2 104 0 0 0 25 O88898 7.83e-58 Tumor protein 63 (p63) (Transformation-related protein 63) (TP63) (Tumor protein p73-like) (p73L) Mus musculus (Mouse) anatomical structure formation involved in morphogenesis [GO:0048646]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular senescence [GO:0090398]; chromatin remodeling [GO:0006338]; cloacal septation [GO:0060197]; cranial skeletal system development [GO:1904888]; ectoderm and mesoderm interaction [GO:0007499]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; epidermal cell differentiation [GO:0009913]; epidermal cell division [GO:0010481]; epidermis development [GO:0008544]; epithelial cell development [GO:0002064]; epithelial cell differentiation [GO:0030855]; establishment of planar polarity [GO:0001736]; establishment of skin barrier [GO:0061436]; female genitalia morphogenesis [GO:0048807]; hair follicle development [GO:0001942]; hair follicle morphogenesis [GO:0031069]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; keratinocyte differentiation [GO:0030216]; keratinocyte proliferation [GO:0043616]; morphogenesis of a polarized epithelium [GO:0001738]; multicellular organism aging [GO:0010259]; negative regulation of cellular senescence [GO:2000773]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of keratinocyte differentiation [GO:0045617]; negative regulation of mesoderm development [GO:2000381]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron apoptotic process [GO:0051402]; Notch signaling pathway [GO:0007219]; odontogenesis of dentin-containing tooth [GO:0042475]; pattern specification process [GO:0007389]; polarized epithelial cell differentiation [GO:0030859]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cell cycle G1/S phase transition [GO:1902808]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of fibroblast apoptotic process [GO:2000271]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of somatic stem cell population maintenance [GO:1904674]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; prostate gland development [GO:0030850]; prostatic bud formation [GO:0060513]; protein tetramerization [GO:0051262]; proximal/distal pattern formation [GO:0009954]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of epidermal cell division [GO:0010482]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal system development [GO:0001501]; skin epidermis development [GO:0098773]; skin morphogenesis [GO:0043589]; spermatogenesis [GO:0007283]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; stem cell differentiation [GO:0048863]; stem cell proliferation [GO:0072089]; sympathetic nervous system development [GO:0048485]; transcription by RNA polymerase II [GO:0006366] GO:0000122; GO:0000785; GO:0000977; GO:0000978; GO:0000981; GO:0001228; GO:0001501; GO:0001736; GO:0001738; GO:0001942; GO:0002039; GO:0002064; GO:0003677; GO:0003682; GO:0003684; GO:0003690; GO:0003700; GO:0005634; GO:0005654; GO:0005737; GO:0005791; GO:0006338; GO:0006357; GO:0006366; GO:0006915; GO:0006974; GO:0007219; GO:0007283; GO:0007389; GO:0007499; GO:0008284; GO:0008544; GO:0009887; GO:0009913; GO:0009954; GO:0010259; GO:0010481; GO:0010482; GO:0010838; GO:0019904; GO:0030216; GO:0030326; GO:0030425; GO:0030850; GO:0030855; GO:0030859; GO:0031069; GO:0032991; GO:0033147; GO:0035115; GO:0035116; GO:0036342; GO:0042475; GO:0042771; GO:0042802; GO:0043005; GO:0043281; GO:0043565; GO:0043589; GO:0043616; GO:0045617; GO:0045669; GO:0045747; GO:0045892; GO:0045893; GO:0045944; GO:0046872; GO:0048485; GO:0048646; GO:0048807; GO:0048863; GO:0050699; GO:0051262; GO:0051402; GO:0060197; GO:0060513; GO:0060529; GO:0061436; GO:0072089; GO:0090398; GO:0097371; GO:0098773; GO:1902808; GO:1904674; GO:1904888; GO:2000271; GO:2000381; GO:2000648; GO:2000773; GO:2001235 41002 XM_044308216.1 26 0 0 12 0 B1AS42 1.68e-55 NADH-cytochrome b5 reductase-like (EC 1.6.2.2) Mus musculus (Mouse) NA GO:0004128; GO:0005654 41003 XM_044317453.1 0 0 1 0 8 Q9VJJ7 2.85e-51 Transient receptor potential-gamma protein (TRPgamma) (Transient receptor potential cation channel gamma) Drosophila melanogaster (Fruit fly) adult walking behavior [GO:0007628]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cation transport [GO:0006812]; detection of light stimulus involved in visual perception [GO:0050908]; neuromuscular process controlling posture [GO:0050884]; regulation of cytosolic calcium ion concentration [GO:0051480]; response to light stimulus [GO:0009416] GO:0005261; GO:0005262; GO:0005886; GO:0006812; GO:0006816; GO:0007628; GO:0008381; GO:0009416; GO:0015279; GO:0016028; GO:0034703; GO:0043025; GO:0050884; GO:0050908; GO:0051480; GO:0070588; GO:0070679; GO:1990635 41004 XM_029345778.2 978 536 576 1244 1170 Q8C6S9 0 Cilia- and flagella-associated protein 54 Mus musculus (Mouse) cerebrospinal fluid circulation [GO:0090660]; cilium assembly [GO:0060271]; cilium movement involved in cell motility [GO:0060294]; establishment of localization in cell [GO:0051649]; mucociliary clearance [GO:0120197]; sperm flagellum assembly [GO:0120316]; spermatogenesis [GO:0007283] GO:0005576; GO:0005930; GO:0007283; GO:0051649; GO:0060271; GO:0060294; GO:0090660; GO:0120197; GO:0120316 41005 XM_029345778.2 978 536 576 1244 1170 Q8C6S9 2.16e-101 Cilia- and flagella-associated protein 54 Mus musculus (Mouse) cerebrospinal fluid circulation [GO:0090660]; cilium assembly [GO:0060271]; cilium movement involved in cell motility [GO:0060294]; establishment of localization in cell [GO:0051649]; mucociliary clearance [GO:0120197]; sperm flagellum assembly [GO:0120316]; spermatogenesis [GO:0007283] GO:0005576; GO:0005930; GO:0007283; GO:0051649; GO:0060271; GO:0060294; GO:0090660; GO:0120197; GO:0120316 41006 XM_044309791.1 65 58 108 96 153 Q3TCX3 6.3e-69 KH homology domain-containing protein 4 (Brings lots of money 7) (Pre-mRNA splicing factor protein Khdc4) Mus musculus (Mouse) mRNA splice site selection [GO:0006376] GO:0003723; GO:0005634; GO:0005654; GO:0005681; GO:0005737; GO:0006376 41007 XM_029344440.2 125 87 85 179 110 Q1PRL4 2.56e-38 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Gallus gallus (Chicken) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 41008 XM_029345807.2 44 8 82 76 191 NA NA NA NA NA NA 41009 XM_044316266.1 10 0 10 3 46 D3YXG0 6.29e-41 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 41010 XM_044316266.1 10 0 10 3 46 D3YXG0 4.11e-33 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 41011 XM_044316266.1 10 0 10 3 46 D3YXG0 2.63e-31 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 41012 XM_044316266.1 10 0 10 3 46 D3YXG0 1.96e-30 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 41013 XM_044316266.1 10 0 10 3 46 D3YXG0 9.64e-30 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 41014 XM_044316266.1 10 0 10 3 46 D3YXG0 1.56e-29 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 41015 XM_044316266.1 10 0 10 3 46 D3YXG0 4.81e-29 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 41016 XM_044316266.1 10 0 10 3 46 D3YXG0 1.55e-28 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 41017 XM_044316266.1 10 0 10 3 46 D3YXG0 1.58e-28 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 41018 XM_044316266.1 10 0 10 3 46 D3YXG0 8.2e-28 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 41019 XM_044316266.1 10 0 10 3 46 D3YXG0 1.18e-27 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 41020 XM_044316266.1 10 0 10 3 46 D3YXG0 1.06e-25 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 41021 XM_044316266.1 10 0 10 3 46 D3YXG0 1.11e-25 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 41022 XM_044316266.1 10 0 10 3 46 D3YXG0 5.35e-24 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 41023 XM_044316266.1 10 0 10 3 46 D3YXG0 1.09e-23 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 41024 XM_044316266.1 10 0 10 3 46 D3YXG0 3.55e-23 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 41025 XM_044316266.1 10 0 10 3 46 D3YXG0 4.04e-23 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 41026 XM_044316266.1 10 0 10 3 46 D3YXG0 5.26e-23 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 41027 XM_044316266.1 10 0 10 3 46 D3YXG0 4.35e-22 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 41028 XM_044316266.1 10 0 10 3 46 D3YXG0 8.98e-22 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 41029 XM_029341544.2 1579 486 398 598 355 B0BLT0 1.6e-32 Zinc finger protein 593 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) ribosome biogenesis [GO:0042254] GO:0003676; GO:0005730; GO:0005737; GO:0008270; GO:0042254; GO:1990275 41030 XM_044322109.1 34 49 1 5 496 Q5AXT5 4.06e-32 ATP-dependent DNA helicase PIF1 (EC 3.6.4.12) (DNA repair and recombination helicase PIF1) Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; mitochondrial genome maintenance [GO:0000002]; telomere maintenance [GO:0000723] GO:0000002; GO:0000723; GO:0003677; GO:0005524; GO:0005634; GO:0005657; GO:0005739; GO:0006260; GO:0006281; GO:0006310; GO:0016887; GO:0032508; GO:0043139 41031 XM_044328425.1 0 29 43 0 10 NA NA NA NA NA NA 41032 XM_029330476.2 0 0 4 0 16 NA NA NA NA NA NA 41033 XM_044323447.1 7 0 0 0 0 NA NA NA NA NA NA 41034 XM_044321866.1 97 68 28 125 148 Q8BYI9 1.31e-65 Tenascin-R (TN-R) (Janusin) (Neural recognition molecule J1-160/180) (Restrictin) Mus musculus (Mouse) associative learning [GO:0008306]; axon extension [GO:0048675]; axon extension involved in regeneration [GO:0048677]; cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198]; locomotory exploration behavior [GO:0035641]; long-term synaptic potentiation [GO:0060291]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of axon extension [GO:0030517]; negative regulation of axon extension involved in regeneration [GO:0048692]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of neuron projection development [GO:0010977]; negative regulation of synaptic transmission [GO:0050805]; neuroblast migration [GO:0097402]; neuromuscular process controlling balance [GO:0050885]; neuron cell-cell adhesion [GO:0007158]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transmission of nerve impulse [GO:0051971]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of cell migration [GO:0030334]; synapse organization [GO:0050808]; synaptic transmission, glutamatergic [GO:0035249]; telencephalon cell migration [GO:0022029] GO:0005102; GO:0005178; GO:0005615; GO:0007155; GO:0007158; GO:0007162; GO:0008306; GO:0009986; GO:0010977; GO:0022029; GO:0022408; GO:0030155; GO:0030198; GO:0030334; GO:0030517; GO:0031012; GO:0035249; GO:0035641; GO:0045121; GO:0045595; GO:0046625; GO:0048675; GO:0048677; GO:0048692; GO:0050804; GO:0050805; GO:0050808; GO:0050885; GO:0051968; GO:0051971; GO:0060291; GO:0062023; GO:0072534; GO:0090733; GO:0097402; GO:0098685; GO:0098686; GO:0098965; GO:0098966; GO:0098978 41035 XM_044310702.1 10 0 1 8 79 NA NA NA NA NA NA 41036 XM_029335358.2 71 106 98 97 79 P30884 1.39e-75 Bone morphogenetic protein 2-B (BMP-2-II) Xenopus laevis (African clawed frog) cartilage development [GO:0051216]; cell differentiation [GO:0030154]; ossification [GO:0001503] GO:0001503; GO:0005125; GO:0005615; GO:0008083; GO:0030154; GO:0051216 41037 XM_044311584.1 879 679 879 867 1196 A7SGU6 2.36e-75 Proteasome assembly chaperone 2 Nematostella vectensis (Starlet sea anemone) proteasome assembly [GO:0043248] GO:0005634; GO:0005829; GO:0043248 41038 XM_044309702.1 0 9 1 6 2 Q96AY4 4.13e-93 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41039 XM_044309702.1 0 9 1 6 2 Q96AY4 4.7e-88 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41040 XM_044309702.1 0 9 1 6 2 Q96AY4 3.44e-84 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41041 XM_044309702.1 0 9 1 6 2 Q96AY4 2.15e-82 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41042 XM_044309702.1 0 9 1 6 2 Q96AY4 1.66e-80 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41043 XM_044309702.1 0 9 1 6 2 Q96AY4 6.74e-72 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41044 XM_044309702.1 0 9 1 6 2 Q96AY4 4.69e-53 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41045 XM_044312464.1 24 0 11 11 10 NA NA NA NA NA NA 41046 XM_029325485.2 15 37 47 29 36 A0JM24 1.13e-47 NADP-dependent oxidoreductase domain-containing protein 1 (EC 1.-.-.-) (Pyrroline-5-carboxylate reductase-like protein C14orf148 homolog) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0016491 41047 XR_006391300.1 0 0 39 8 0 NA NA NA NA NA NA 41048 XM_044312311.1 5 12 14 26 76 Q9UBN7 7.92e-33 Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-) Homo sapiens (Human) aggresome assembly [GO:0070842]; autophagy [GO:0006914]; axonal transport of mitochondrion [GO:0019896]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to misfolded protein [GO:0071218]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to topologically incorrect protein [GO:0035967]; cilium assembly [GO:0060271]; cilium disassembly [GO:0061523]; collateral sprouting [GO:0048668]; dendritic spine morphogenesis [GO:0060997]; epigenetic regulation of gene expression [GO:0040029]; histone deacetylation [GO:0016575]; Hsp90 deacetylation [GO:0070846]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of protein-containing complex disassembly [GO:0043242]; negative regulation of proteolysis [GO:0045861]; negative regulation of transcription by RNA polymerase II [GO:0000122]; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:0061734]; peptidyl-lysine deacetylation [GO:0034983]; polyubiquitinated misfolded protein transport [GO:0070845]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of hydrogen peroxide-mediated programmed cell death [GO:1901300]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of tubulin deacetylation [GO:0090044]; protein deacetylation [GO:0006476]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; protein-containing complex disassembly [GO:0032984]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of autophagy [GO:0010506]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of establishment of protein localization [GO:0070201]; regulation of fat cell differentiation [GO:0045598]; regulation of macroautophagy [GO:0016241]; regulation of microtubule-based movement [GO:0060632]; regulation of protein stability [GO:0031647]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]; response to dexamethasone [GO:0071548]; response to growth factor [GO:0070848]; response to immobilization stress [GO:0035902]; response to misfolded protein [GO:0051788]; tubulin deacetylation [GO:0090042]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] GO:0000118; GO:0000122; GO:0000209; GO:0000978; GO:0001222; GO:0001975; GO:0003779; GO:0004407; GO:0005634; GO:0005654; GO:0005737; GO:0005771; GO:0005813; GO:0005829; GO:0005874; GO:0005875; GO:0005901; GO:0006476; GO:0006515; GO:0006886; GO:0006914; GO:0007026; GO:0008013; GO:0008017; GO:0008270; GO:0010506; GO:0010634; GO:0010727; GO:0016234; GO:0016235; GO:0016241; GO:0016575; GO:0019896; GO:0019899; GO:0030424; GO:0030425; GO:0031252; GO:0031333; GO:0031593; GO:0031625; GO:0031647; GO:0031648; GO:0032418; GO:0032984; GO:0033138; GO:0033558; GO:0034983; GO:0035902; GO:0035967; GO:0036064; GO:0040029; GO:0042826; GO:0042903; GO:0043014; GO:0043130; GO:0043162; GO:0043204; GO:0043242; GO:0045598; GO:0045861; GO:0045892; GO:0048156; GO:0048471; GO:0048487; GO:0048668; GO:0048843; GO:0050775; GO:0051354; GO:0051412; GO:0051787; GO:0051788; GO:0051879; GO:0051968; GO:0060271; GO:0060632; GO:0060765; GO:0060997; GO:0061523; GO:0061734; GO:0070201; GO:0070301; GO:0070840; GO:0070842; GO:0070845; GO:0070846; GO:0070848; GO:0071218; GO:0071374; GO:0071548; GO:0090042; GO:0090044; GO:1901300; GO:1901984; GO:1903146; GO:1903223; GO:1904056; GO:1904115; GO:2000273 41049 XM_044312311.1 5 12 14 26 76 Q9UBN7 4.5e-30 Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-) Homo sapiens (Human) aggresome assembly [GO:0070842]; autophagy [GO:0006914]; axonal transport of mitochondrion [GO:0019896]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to misfolded protein [GO:0071218]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to topologically incorrect protein [GO:0035967]; cilium assembly [GO:0060271]; cilium disassembly [GO:0061523]; collateral sprouting [GO:0048668]; dendritic spine morphogenesis [GO:0060997]; epigenetic regulation of gene expression [GO:0040029]; histone deacetylation [GO:0016575]; Hsp90 deacetylation [GO:0070846]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of protein-containing complex disassembly [GO:0043242]; negative regulation of proteolysis [GO:0045861]; negative regulation of transcription by RNA polymerase II [GO:0000122]; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:0061734]; peptidyl-lysine deacetylation [GO:0034983]; polyubiquitinated misfolded protein transport [GO:0070845]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of hydrogen peroxide-mediated programmed cell death [GO:1901300]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of tubulin deacetylation [GO:0090044]; protein deacetylation [GO:0006476]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; protein-containing complex disassembly [GO:0032984]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of autophagy [GO:0010506]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of establishment of protein localization [GO:0070201]; regulation of fat cell differentiation [GO:0045598]; regulation of macroautophagy [GO:0016241]; regulation of microtubule-based movement [GO:0060632]; regulation of protein stability [GO:0031647]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]; response to dexamethasone [GO:0071548]; response to growth factor [GO:0070848]; response to immobilization stress [GO:0035902]; response to misfolded protein [GO:0051788]; tubulin deacetylation [GO:0090042]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] GO:0000118; GO:0000122; GO:0000209; GO:0000978; GO:0001222; GO:0001975; GO:0003779; GO:0004407; GO:0005634; GO:0005654; GO:0005737; GO:0005771; GO:0005813; GO:0005829; GO:0005874; GO:0005875; GO:0005901; GO:0006476; GO:0006515; GO:0006886; GO:0006914; GO:0007026; GO:0008013; GO:0008017; GO:0008270; GO:0010506; GO:0010634; GO:0010727; GO:0016234; GO:0016235; GO:0016241; GO:0016575; GO:0019896; GO:0019899; GO:0030424; GO:0030425; GO:0031252; GO:0031333; GO:0031593; GO:0031625; GO:0031647; GO:0031648; GO:0032418; GO:0032984; GO:0033138; GO:0033558; GO:0034983; GO:0035902; GO:0035967; GO:0036064; GO:0040029; GO:0042826; GO:0042903; GO:0043014; GO:0043130; GO:0043162; GO:0043204; GO:0043242; GO:0045598; GO:0045861; GO:0045892; GO:0048156; GO:0048471; GO:0048487; GO:0048668; GO:0048843; GO:0050775; GO:0051354; GO:0051412; GO:0051787; GO:0051788; GO:0051879; GO:0051968; GO:0060271; GO:0060632; GO:0060765; GO:0060997; GO:0061523; GO:0061734; GO:0070201; GO:0070301; GO:0070840; GO:0070842; GO:0070845; GO:0070846; GO:0070848; GO:0071218; GO:0071374; GO:0071548; GO:0090042; GO:0090044; GO:1901300; GO:1901984; GO:1903146; GO:1903223; GO:1904056; GO:1904115; GO:2000273 41050 XR_006392092.1 300 3 80 0 299 NA NA NA NA NA NA 41051 XM_044308149.1 89 129 65 237 123 NA NA NA NA NA NA 41052 XM_044327442.1 1171 1136 1599 1291 2004 Q5F3Z9 5.39e-41 Zinc finger CCCH domain-containing protein 14 Gallus gallus (Chicken) negative regulation of mRNA polyadenylation [GO:1900364]; regulation of mRNA stability [GO:0043488] GO:0005634; GO:0005737; GO:0008143; GO:0016607; GO:0043488; GO:0046872; GO:1900364 41053 XM_044327442.1 1171 1136 1599 1291 2004 Q5F3Z9 4.07e-25 Zinc finger CCCH domain-containing protein 14 Gallus gallus (Chicken) negative regulation of mRNA polyadenylation [GO:1900364]; regulation of mRNA stability [GO:0043488] GO:0005634; GO:0005737; GO:0008143; GO:0016607; GO:0043488; GO:0046872; GO:1900364 41054 XR_003823056.2 0 11 0 0 28 NA NA NA NA NA NA 41055 XM_044317615.1 385 328 126 506 944 P0DXD2 7.77e-30 NA NA NA NA 41056 XM_029339882.2 876 851 354 1337 1668 Q6P0U3 2.84e-29 Ras-like protein family member 11B (EC 3.6.5.2) Danio rerio (Zebrafish) (Brachydanio rerio) mesendoderm development [GO:0048382] GO:0003925; GO:0005525; GO:0048382 41057 XM_044311466.1 289 123 48 235 485 NA NA NA NA NA NA 41058 XM_029326397.2 54 50 75 40 279 P62597 7.77e-33 Protection of telomeres protein 1 (cPot1) (POT1-like telomere end-binding protein) Gallus gallus (Chicken) negative regulation of telomerase activity [GO:0051974]; regulation of telomere maintenance via telomerase [GO:0032210]; telomere capping [GO:0016233]; telomere maintenance via telomerase [GO:0007004] GO:0000781; GO:0000783; GO:0005654; GO:0007004; GO:0010521; GO:0016233; GO:0032210; GO:0043047; GO:0051974; GO:0098505 41059 XR_003824238.2 0 3 11 13 14 NA NA NA NA NA NA 41060 XM_044310474.1 0 86 0 115 0 NA NA NA NA NA NA 41061 XM_044328437.1 108 56 42 64 159 Q16960 0 Dynein intermediate chain 3, ciliary Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina) NA GO:0005737; GO:0005874; GO:0005929; GO:0030286 41062 XM_029342897.2 0 6 1 4 55 NA NA NA NA NA NA 41063 XR_006392540.1 37 63 27 21 3 NA NA NA NA NA NA 41064 XM_044321380.1 0 23 26 5 81 NA NA NA NA NA NA 41065 XM_029339049.2 1187 1575 820 2952 1514 Q9C098 8.82e-106 Serine/threonine-protein kinase DCLK3 (EC 2.7.11.1) (Doublecortin domain-containing protein 3C) (Doublecortin-like and CAM kinase-like 3) (Doublecortin-like kinase 3) Homo sapiens (Human) peptidyl-serine phosphorylation [GO:0018105] GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0018105; GO:0106310 41066 XM_029331240.2 997 802 940 1155 1635 Q64737 0 Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (Glycinamide ribonucleotide synthetase) (GARS) (Phosphoribosylglycinamide synthetase); Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIR synthase) (AIRS) (Phosphoribosyl-aminoimidazole synthetase); Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) (5'-phosphoribosylglycinamide transformylase) (GAR transformylase) (GART)] Mus musculus (Mouse) 'de novo' AMP biosynthetic process [GO:0044208]; 'de novo' IMP biosynthetic process [GO:0006189]; 'de novo' XMP biosynthetic process [GO:0097294]; adenine biosynthetic process [GO:0046084]; brainstem development [GO:0003360]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; glycine metabolic process [GO:0006544]; GMP biosynthetic process [GO:0006177]; purine nucleotide biosynthetic process [GO:0006164]; response to inorganic substance [GO:0010035]; response to organic substance [GO:0010033]; ribonucleoside monophosphate biosynthetic process [GO:0009156]; tetrahydrofolate biosynthetic process [GO:0046654] GO:0003360; GO:0004637; GO:0004641; GO:0004644; GO:0005524; GO:0005829; GO:0006164; GO:0006177; GO:0006189; GO:0006544; GO:0009156; GO:0010033; GO:0010035; GO:0021549; GO:0021987; GO:0044208; GO:0046084; GO:0046654; GO:0046872; GO:0097294 41067 XM_044321287.1 48 18 183 0 535 Q7RTR2 6.63e-39 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 41068 XM_044321287.1 48 18 183 0 535 Q7RTR2 1.01e-35 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 41069 XM_044321287.1 48 18 183 0 535 Q7RTR2 6.08e-32 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 41070 XM_044321287.1 48 18 183 0 535 Q7RTR2 3.88e-30 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 41071 XM_044321287.1 48 18 183 0 535 Q7RTR2 5.52e-29 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 41072 XM_029335878.2 97 59 39 69 15 O15973 1.22e-30 Rhodopsin, GQ-coupled (GQ-rhodopsin) Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis) phototransduction [GO:0007602]; visual perception [GO:0007601] GO:0004930; GO:0005886; GO:0007601; GO:0007602; GO:0009881 41073 XM_029336054.2 595 544 330 541 738 A6H6W9 1.81e-64 Sin3 histone deacetylase corepressor complex component SDS3 (Suppressor of defective silencing 3 protein homolog) Bos taurus (Bovine) apoptotic process [GO:0006915]; chromatin organization [GO:0006325]; histone deacetylation [GO:0016575]; negative regulation of cell migration [GO:0030336]; negative regulation of stem cell population maintenance [GO:1902455]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; positive regulation of apoptotic process [GO:0043065]; positive regulation of stem cell population maintenance [GO:1902459] GO:0000122; GO:0005634; GO:0006325; GO:0006915; GO:0016575; GO:0030336; GO:0030512; GO:0042826; GO:0043065; GO:0070822; GO:1902455; GO:1902459 41074 XM_029349496.2 0 9 0 38 4 Q4U4D2 1.78e-47 Melanopsin (Opsin-4) Podarcis siculus (Italian wall lizard) phototransduction [GO:0007602]; visual perception [GO:0007601] GO:0004930; GO:0005886; GO:0007601; GO:0007602; GO:0009881 41075 XM_044313754.1 0 0 0 20 31 O04369 1.24e-21 Rac-like GTP-binding protein RAC1 Lotus japonicus (Lotus corniculatus var. japonicus) small GTPase mediated signal transduction [GO:0007264] GO:0003924; GO:0005525; GO:0005737; GO:0007264; GO:0016020 41076 XM_044326210.1 18 1 30 0 70 NA NA NA NA NA NA 41077 XR_006394432.1 74 172 60 154 73 NA NA NA NA NA NA 41078 XM_029341336.2 124 0 0 0 0 NA NA NA NA NA NA 41079 XM_044323231.1 1936 1386 1070 1462 2068 Q9DBC0 1.37e-52 Protein adenylyltransferase SelO, mitochondrial (EC 2.7.7.-) (EC 2.7.7.108) (Selenoprotein O) (SelO) Mus musculus (Mouse) protein adenylylation [GO:0018117] GO:0005524; GO:0005694; GO:0005739; GO:0018117; GO:0046872; GO:0070733 41080 XM_029345902.2 48 15 30 15 67 O43614 5.29e-23 Orexin receptor type 2 (Ox-2-R) (Ox2-R) (Ox2R) (Hypocretin receptor type 2) Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; circadian sleep/wake cycle process [GO:0022410]; feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; locomotion [GO:0040011]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; regulation of circadian sleep/wake cycle, wakefulness [GO:0010840]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0004930; GO:0005886; GO:0007186; GO:0007200; GO:0007218; GO:0007268; GO:0007631; GO:0008188; GO:0010840; GO:0016499; GO:0017046; GO:0022410; GO:0040011; GO:0045202; GO:0051480 41081 XM_044327297.1 6 0 24 0 11 NA NA NA NA NA NA 41082 XM_029347805.2 885 877 452 259 472 NA NA NA NA NA NA 41083 XM_029358333.2 2648 1705 1097 2157 1843 Q8JFV8 2.56e-41 Synaptic vesicle membrane protein VAT-1 homolog (EC 1.-.-.-) Danio rerio (Zebrafish) (Brachydanio rerio) negative regulation of mitochondrial fusion [GO:0010637] GO:0005741; GO:0008270; GO:0010637; GO:0016491 41084 XM_044327538.1 13 93 0 20 89 Q2LMP1 5.91e-112 Protein Wnt-3a Gallus gallus (Chicken) BMP signaling pathway [GO:0030509]; canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; cornea development in camera-type eye [GO:0061303]; determination of dorsal identity [GO:0048263]; dorsal/ventral pattern formation [GO:0009953]; inner ear morphogenesis [GO:0042472]; limb development [GO:0060173]; limb morphogenesis [GO:0035108]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of fibroblast growth factor receptor signaling pathway [GO:0045743]; positive regulation of gene expression [GO:0010628]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of myotube differentiation [GO:0010831]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of fibroblast growth factor receptor signaling pathway [GO:0040036] GO:0005109; GO:0005125; GO:0005615; GO:0005640; GO:0005783; GO:0005829; GO:0005886; GO:0009953; GO:0010628; GO:0010831; GO:0030182; GO:0030509; GO:0035108; GO:0040036; GO:0042472; GO:0045165; GO:0045663; GO:0045743; GO:0045944; GO:0048263; GO:0050679; GO:0060070; GO:0060173; GO:0060828; GO:0061303; GO:0090263 41085 XM_044307374.1 353 384 310 328 415 F1QCP6 8.39e-86 Tafazzin (Taz) (EC 2.3.1.-) Danio rerio (Zebrafish) (Brachydanio rerio) cardiolipin acyl-chain remodeling [GO:0035965]; cardiolipin metabolic process [GO:0032048]; heart development [GO:0007507]; heart looping [GO:0001947]; inner mitochondrial membrane organization [GO:0007007]; mitophagy [GO:0000423]; positive regulation of heart contraction [GO:0045823] GO:0000423; GO:0001947; GO:0005739; GO:0005741; GO:0005743; GO:0007007; GO:0007507; GO:0008374; GO:0031966; GO:0032048; GO:0035965; GO:0045823; GO:0047184 41086 XM_044325298.1 227 68 190 164 294 NA NA NA NA NA NA 41087 XM_044308496.1 327 53 270 275 822 P70490 9.52e-51 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41088 XM_044308496.1 327 53 270 275 822 P70490 1.15e-48 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41089 XM_044308496.1 327 53 270 275 822 P70490 1.67e-48 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41090 XM_044308496.1 327 53 270 275 822 P70490 2.32e-47 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41091 XM_044308496.1 327 53 270 275 822 P70490 2.95e-47 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41092 XM_044308496.1 327 53 270 275 822 P70490 6.78e-47 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41093 XM_044308496.1 327 53 270 275 822 P70490 3e-46 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41094 XM_044308496.1 327 53 270 275 822 P70490 9.71e-46 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41095 XM_044308496.1 327 53 270 275 822 P70490 1.12e-44 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41096 XM_044308496.1 327 53 270 275 822 P70490 4.36e-44 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41097 XM_044308496.1 327 53 270 275 822 P70490 6.73e-44 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41098 XM_044308496.1 327 53 270 275 822 P70490 1.19e-43 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41099 XM_044308496.1 327 53 270 275 822 P70490 3.39e-43 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41100 XM_044308496.1 327 53 270 275 822 P70490 3.55e-43 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41101 XM_044308496.1 327 53 270 275 822 P70490 4.25e-43 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41102 XM_044308496.1 327 53 270 275 822 P70490 4.29e-43 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41103 XM_044308496.1 327 53 270 275 822 P70490 9.96e-43 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41104 XM_044308496.1 327 53 270 275 822 P70490 1.13e-42 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41105 XM_044308496.1 327 53 270 275 822 P70490 4.07e-42 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41106 XM_044308496.1 327 53 270 275 822 P70490 4.51e-42 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41107 XM_044308496.1 327 53 270 275 822 P70490 7.87e-42 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41108 XM_044308496.1 327 53 270 275 822 P70490 1.5e-41 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41109 XM_044308496.1 327 53 270 275 822 P70490 1.52e-41 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41110 XM_044308496.1 327 53 270 275 822 P70490 1.61e-41 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41111 XM_044308496.1 327 53 270 275 822 P70490 3.53e-41 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41112 XM_044308496.1 327 53 270 275 822 P70490 3.92e-41 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41113 XM_044308496.1 327 53 270 275 822 P70490 3.92e-41 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41114 XM_044308496.1 327 53 270 275 822 P70490 4.86e-41 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41115 XM_044308496.1 327 53 270 275 822 P70490 7.72e-41 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41116 XM_044308496.1 327 53 270 275 822 P70490 1.87e-40 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41117 XM_044308496.1 327 53 270 275 822 P70490 1.89e-40 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41118 XM_044308496.1 327 53 270 275 822 P70490 2.92e-40 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41119 XM_044308496.1 327 53 270 275 822 P70490 6.03e-40 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41120 XM_044308496.1 327 53 270 275 822 P70490 6.2e-40 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41121 XM_044308496.1 327 53 270 275 822 P70490 8.3e-40 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41122 XM_044308496.1 327 53 270 275 822 P70490 8.62e-40 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41123 XM_044308496.1 327 53 270 275 822 P70490 2.34e-39 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41124 XM_044308496.1 327 53 270 275 822 P70490 3.19e-39 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41125 XM_044308496.1 327 53 270 275 822 P70490 5.36e-39 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41126 XM_044308496.1 327 53 270 275 822 P70490 1.51e-38 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41127 XM_044308496.1 327 53 270 275 822 P70490 1.55e-38 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41128 XM_044308496.1 327 53 270 275 822 P70490 1.86e-38 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41129 XM_044308496.1 327 53 270 275 822 P70490 5.08e-38 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41130 XM_044308496.1 327 53 270 275 822 P70490 6.42e-38 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41131 XM_044308496.1 327 53 270 275 822 P70490 2.04e-37 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41132 XM_044308496.1 327 53 270 275 822 P70490 3.39e-37 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41133 XM_044308496.1 327 53 270 275 822 P70490 6.3e-37 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41134 XM_044308496.1 327 53 270 275 822 P70490 1.09e-36 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41135 XM_044308496.1 327 53 270 275 822 P70490 1.35e-36 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41136 XM_044308496.1 327 53 270 275 822 P70490 6.17e-36 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41137 XM_044308496.1 327 53 270 275 822 P70490 1.24e-35 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41138 XM_044308496.1 327 53 270 275 822 P70490 3.77e-35 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41139 XM_044308496.1 327 53 270 275 822 P70490 4.63e-35 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41140 XM_044308496.1 327 53 270 275 822 P70490 9.99e-35 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41141 XM_044308496.1 327 53 270 275 822 P70490 2.15e-34 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41142 XM_044308496.1 327 53 270 275 822 P70490 3.5e-34 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41143 XM_044308496.1 327 53 270 275 822 P70490 3.64e-34 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41144 XM_044308496.1 327 53 270 275 822 P70490 1.06e-33 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41145 XM_044308496.1 327 53 270 275 822 P70490 4.9e-33 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41146 XM_044308496.1 327 53 270 275 822 P70490 5.53e-33 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41147 XM_044308496.1 327 53 270 275 822 P70490 9.08e-33 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41148 XM_044308496.1 327 53 270 275 822 P70490 2.68e-32 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41149 XM_044308496.1 327 53 270 275 822 P70490 1.78e-27 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 41150 XM_044309902.1 101 64 6 25 108 P10394 1.23e-29 Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 41151 XM_029328181.2 805 408 507 674 551 NA NA NA NA NA NA 41152 XR_006392120.1 10 3 20 12 6 NA NA NA NA NA NA 41153 XM_044310471.1 0 727 334 1747 6 NA NA NA NA NA NA 41154 XM_029337149.2 1669 917 1365 1470 1646 F1MBP6 5.78e-41 Kelch-like protein 3 Bos taurus (Bovine) distal tubule morphogenesis [GO:0072156]; gene expression [GO:0010467]; ion homeostasis [GO:0050801]; potassium ion homeostasis [GO:0055075]; protein K48-linked ubiquitination [GO:0070936]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; renal sodium ion absorption [GO:0070294]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0003779; GO:0005829; GO:0005856; GO:0006468; GO:0006511; GO:0010467; GO:0016567; GO:0031463; GO:0050801; GO:0055075; GO:0070294; GO:0070936; GO:0072156; GO:0097602 41155 XM_044326629.1 41 36 126 81 192 NA NA NA NA NA NA 41156 XM_044326555.1 0 0 18 15 8 NA NA NA NA NA NA 41157 XR_006395520.1 7 10 0 0 6 NA NA NA NA NA NA 41158 XR_006398158.1 0 0 0 0 39 NA NA NA NA NA NA 41159 XR_006397158.1 57 0 15 0 39 NA NA NA NA NA NA 41160 XM_044310290.1 18 0 28 4 19 NA NA NA NA NA NA 41161 XM_029335026.2 104 22 36 24 167 Q3TC93 1.16e-23 HCLS1-binding protein 3 (HS1-binding protein 3) (HSP1BP-3) Mus musculus (Mouse) cell surface receptor signaling pathway [GO:0007166]; regulation of apoptotic process [GO:0042981]; T cell differentiation [GO:0030217] GO:0005739; GO:0005783; GO:0007166; GO:0030217; GO:0035091; GO:0042981 41162 XM_029337868.2 26 254 0 347 102 Q5FWR0 0 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.4.12) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) DNA double-strand break processing [GO:0000729] GO:0000729; GO:0003677; GO:0004386; GO:0005524; GO:0005634; GO:0016887; GO:0035861; GO:0043130; GO:0140658 41163 XM_029339175.2 282 245 162 315 361 Q5BIR6 5.3e-141 Mediator of RNA polymerase II transcription subunit 17 (Cofactor required for Sp1 transcriptional activation subunit 6) (CRSP complex subunit 6) (Mediator complex subunit 17) Bos taurus (Bovine) positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; regulation of transcription by RNA polymerase II [GO:0006357]; somatic stem cell population maintenance [GO:0035019] GO:0003712; GO:0006357; GO:0016592; GO:0030374; GO:0035019; GO:0046966; GO:0060261; GO:0070847 41164 XM_029329156.2 19587 25342 11489 16876 6385 NA NA NA NA NA NA 41165 XM_029331136.2 3681 3104 1855 3441 3951 Q03049 1.3e-39 Putative uncharacterized oxidoreductase YDR541C (EC 1.1.1.-) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) response to furfural [GO:1901426] GO:0016616; GO:0033721; GO:1901426 41166 XM_029342633.2 16 29 15 10 55 NA NA NA NA NA NA 41167 XM_029335702.2 289 112 154 206 410 Q5ZKD5 0 RRP12-like protein Gallus gallus (Chicken) rRNA processing [GO:0006364] GO:0005730; GO:0006364; GO:0031965 41168 XM_029346123.2 14120 18718 8090 15833 15804 Q5BIP8 7.71e-79 DnaJ homolog subfamily B member 5 Bos taurus (Bovine) chaperone cofactor-dependent protein refolding [GO:0051085] GO:0005829; GO:0051082; GO:0051085; GO:0051087 41169 XM_044327267.1 87 14 48 244 112 NA NA NA NA NA NA 41170 XM_029357690.2 876 466 418 778 732 A9YUB5 1.11e-43 Ubiquitin-related modifier 1 Capra hircus (Goat) protein urmylation [GO:0032447]; tRNA thio-modification [GO:0034227]; tRNA wobble uridine modification [GO:0002098] GO:0002098; GO:0005829; GO:0032447; GO:0034227 41171 XR_006393987.1 33 48 10 28 41 NA NA NA NA NA NA 41172 XM_029330087.2 22 26 16 25 34 NA NA NA NA NA NA 41173 XM_029328240.2 0 10 0 0 4 NA NA NA NA NA NA 41174 XM_044321505.1 269 110 169 272 230 NA NA NA NA NA NA 41175 XM_029341847.2 506 465 342 582 758 B1WB17 2.88e-26 Partner of Y14 and mago (PYM homolog 1 exon junction complex-associated factor) (Protein wibg homolog) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) exon-exon junction complex disassembly [GO:1903259]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of translation [GO:0045727] GO:0000184; GO:0005654; GO:0005730; GO:0005737; GO:0035145; GO:0043022; GO:0045727; GO:1903259 41176 XM_029333587.2 384 2016 595 903 591 Q9UKT5 7.76e-41 F-box only protein 4 Homo sapiens (Human) aging [GO:0007568]; cellular homeostasis [GO:0019725]; cellular response to ionizing radiation [GO:0071479]; common myeloid progenitor cell proliferation [GO:0035726]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of protein localization to nucleus [GO:1900181]; positive regulation of protein polyubiquitination [GO:1902916]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of telomere maintenance via telomerase [GO:0032212]; post-transcriptional regulation of gene expression [GO:0010608]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of DNA damage checkpoint [GO:2000001]; regulation of protein stability [GO:0031647]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; telomere maintenance [GO:0000723]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000151; GO:0000209; GO:0000723; GO:0004842; GO:0005737; GO:0005829; GO:0006511; GO:0007568; GO:0010608; GO:0016567; GO:0019005; GO:0019725; GO:0031146; GO:0031398; GO:0031647; GO:0031648; GO:0032212; GO:0035726; GO:0042803; GO:0048147; GO:0061630; GO:0071479; GO:1900181; GO:1902916; GO:2000001 41177 XM_044323246.1 62 32 88 116 178 NA NA NA NA NA NA 41178 XM_044314561.1 0 0 0 42 15 NA NA NA NA NA NA 41179 XM_029341737.2 18 0 13 7 21 Q9BRB3 3.48e-43 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q (N-acetylglucosamyl transferase component GPI1) (Phosphatidylinositol-glycan biosynthesis class Q protein) (PIG-Q) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; GPI anchor biosynthetic process [GO:0006506] GO:0000506; GO:0005783; GO:0005789; GO:0005975; GO:0006506 41180 XM_044312844.1 2 0 3 0 9 NA NA NA NA NA NA 41181 XM_044316617.1 115 9 5 0 86 NA NA NA NA NA NA 41182 XM_029337546.2 180 68 157 96 525 NA NA NA NA NA NA 41183 XM_044315207.1 76 29 78 110 29 Q80XJ3 8.84e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 41184 XM_044315207.1 76 29 78 110 29 Q80XJ3 4.53e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 41185 XM_044315207.1 76 29 78 110 29 Q80XJ3 1.19e-37 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 41186 XM_044315207.1 76 29 78 110 29 Q80XJ3 5.06e-37 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 41187 XM_044315207.1 76 29 78 110 29 Q80XJ3 1.53e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 41188 XM_044315207.1 76 29 78 110 29 Q80XJ3 2.81e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 41189 XM_044315207.1 76 29 78 110 29 Q80XJ3 1.09e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 41190 XM_044315207.1 76 29 78 110 29 Q80XJ3 1.14e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 41191 XM_044315207.1 76 29 78 110 29 Q80XJ3 8.49e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 41192 XM_044315207.1 76 29 78 110 29 Q80XJ3 6.56e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 41193 XM_044315207.1 76 29 78 110 29 Q80XJ3 1.06e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 41194 XM_029334264.2 0 8 0 0 24 NA NA NA NA NA NA 41195 XM_044318778.1 103 0 54 61 27 NA NA NA NA NA NA 41196 XM_029331752.2 134 39 63 81 148 Q9BRS2 1.3e-173 Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (EC 3.6.3.-) (RIO kinase 1) Homo sapiens (Human) maturation of SSU-rRNA [GO:0030490]; phosphorylation [GO:0016310]; positive regulation of rRNA processing [GO:2000234]; ribosomal small subunit biogenesis [GO:0042274] GO:0004674; GO:0005524; GO:0005654; GO:0005829; GO:0016310; GO:0016787; GO:0030490; GO:0030688; GO:0034708; GO:0042274; GO:0046872; GO:0106310; GO:2000234 41197 XM_044320691.1 0 0 4 0 35 P98133 1.11e-56 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 41198 XM_044320691.1 0 0 4 0 35 P98133 2.31e-47 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 41199 XM_044320691.1 0 0 4 0 35 P98133 2.6e-42 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 41200 XM_044320691.1 0 0 4 0 35 P98133 1.83e-36 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 41201 XM_044320691.1 0 0 4 0 35 P98133 2.32e-35 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 41202 XM_044320691.1 0 0 4 0 35 P98133 5.38e-33 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 41203 XM_044320691.1 0 0 4 0 35 P98133 1.5e-31 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 41204 XM_044320691.1 0 0 4 0 35 P98133 3.81e-30 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 41205 XM_044320691.1 0 0 4 0 35 P98133 3.03e-29 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 41206 XM_044320691.1 0 0 4 0 35 P98133 2.27e-28 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 41207 XM_044320691.1 0 0 4 0 35 P98133 4.86e-28 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 41208 XM_044320691.1 0 0 4 0 35 P98133 1.07e-27 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 41209 XM_044320691.1 0 0 4 0 35 P98133 1.04e-24 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 41210 XM_044320691.1 0 0 4 0 35 P98133 6.47e-24 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 41211 XM_044320691.1 0 0 4 0 35 P98133 3.03e-22 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 41212 XM_044328756.1 0 0 0 0 6 NA NA NA NA NA NA 41213 XM_044323215.1 0 0 12 3 65 NA NA NA NA NA NA 41214 XM_044311590.1 30 17 17 59 26 NA NA NA NA NA NA 41215 XM_044307653.1 37 13 22 16 13 NA NA NA NA NA NA 41216 XM_029355393.2 386 234 163 185 425 NA NA NA NA NA NA 41217 XM_029324848.2 235 9 1 180 109 Q9VEU6 4.63e-111 Soluble guanylate cyclase 89Da (EC 4.6.1.2) Drosophila melanogaster (Fruit fly) cGMP-mediated signaling [GO:0019934]; nitric oxide-cGMP-mediated signaling pathway [GO:0038060]; response to hypoxia [GO:0001666]; response to oxygen levels [GO:0070482]; response to reactive oxygen species [GO:0000302] GO:0000302; GO:0001666; GO:0004383; GO:0005525; GO:0008074; GO:0019899; GO:0019934; GO:0020037; GO:0038060; GO:0046872; GO:0070482 41218 XM_029326269.2 747 1796 7953 3514 7520 NA NA NA NA NA NA 41219 XM_044314209.1 318 486 291 350 244 Q96AY4 9.17e-95 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41220 XM_044314209.1 318 486 291 350 244 Q96AY4 4.18e-94 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41221 XM_044314209.1 318 486 291 350 244 Q96AY4 1.84e-86 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41222 XM_044314209.1 318 486 291 350 244 Q96AY4 3.38e-86 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41223 XM_044314209.1 318 486 291 350 244 Q96AY4 4.67e-85 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41224 XM_044314209.1 318 486 291 350 244 Q96AY4 1.29e-84 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41225 XM_044314209.1 318 486 291 350 244 Q96AY4 1.63e-79 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41226 XM_044314209.1 318 486 291 350 244 Q96AY4 1.24e-73 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41227 XM_044314209.1 318 486 291 350 244 Q96AY4 7.46e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41228 XM_044314209.1 318 486 291 350 244 Q96AY4 1.14e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41229 XM_029343538.2 130 42 76 48 83 NA NA NA NA NA NA 41230 XR_003826722.2 73 14 53 62 79 NA NA NA NA NA NA 41231 XM_044310666.1 21 16 0 10 3 B3EWZ8 2.56e-23 Ectin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 41232 XR_003828104.2 3 46 0 0 0 NA NA NA NA NA NA 41233 XM_044317738.1 729 387 688 1489 445 Q69ZM6 0 Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog) Mus musculus (Mouse) axoneme assembly [GO:0035082]; brain development [GO:0007420]; cilium assembly [GO:0060271]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; positive regulation of hh target transcription factor activity [GO:0007228]; positive regulation of smoothened signaling pathway [GO:0045880]; post-embryonic development [GO:0009791]; protein phosphorylation [GO:0006468]; regulation of DNA-binding transcription factor activity [GO:0051090]; smoothened signaling pathway [GO:0007224] GO:0001222; GO:0003351; GO:0004674; GO:0005524; GO:0005576; GO:0005634; GO:0005737; GO:0005829; GO:0005856; GO:0006468; GO:0007224; GO:0007228; GO:0007420; GO:0009791; GO:0035082; GO:0042995; GO:0045880; GO:0046872; GO:0051090; GO:0060271; GO:0106310 41234 XM_044319906.1 0 0 0 0 6 Q28FE8 2.03e-38 tRNA-specific adenosine deaminase 1 (EC 3.5.4.34) (tRNA-specific adenosine-37 deaminase) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) tRNA processing [GO:0008033] GO:0003723; GO:0008033; GO:0008251; GO:0046872 41235 XM_029349178.2 146 137 130 131 264 NA NA NA NA NA NA 41236 XM_029328371.2 714 523 439 1026 1151 B0JZG0 0 Solute carrier family 23 member 2 (Na(+)/L-ascorbic acid transporter 2) (Sodium-dependent vitamin C transporter 2) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) sodium ion transport [GO:0006814] GO:0006814; GO:0015229; GO:0015293; GO:0098590 41237 XM_029346293.2 4 92 75 154 152 Q05AL1 0 Armadillo repeat-containing protein 8 Danio rerio (Zebrafish) (Brachydanio rerio) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] GO:0000151; GO:0005634; GO:0005737; GO:0034657; GO:0043161 41238 XM_029341443.2 106 146 131 147 41 Q6NUT3 1.19e-78 Major facilitator superfamily domain-containing protein 12 Homo sapiens (Human) carbohydrate transport [GO:0008643]; cysteine transmembrane transport [GO:1903712]; melanin biosynthetic process [GO:0042438]; negative regulation of melanin biosynthetic process [GO:0048022]; organic substance transport [GO:0071702]; pigment metabolic process involved in pigmentation [GO:0043474]; regulation of melanin biosynthetic process [GO:0048021] GO:0005764; GO:0005765; GO:0005770; GO:0005886; GO:0008643; GO:0015293; GO:0033162; GO:0033229; GO:0042438; GO:0042470; GO:0043474; GO:0048021; GO:0048022; GO:0071702; GO:1903712 41239 XM_029358626.2 192 140 91 160 194 Q5BIM8 5.41e-134 DNA excision repair protein ERCC-8 Bos taurus (Bovine) cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair via classical nonhomologous end joining [GO:0097680]; positive regulation of DNA repair [GO:0045739]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of transcription-coupled nucleotide-excision repair [GO:0090262]; response to oxidative stress [GO:0006979]; response to UV [GO:0009411]; response to X-ray [GO:0010165]; single strand break repair [GO:0000012]; transcription-coupled nucleotide-excision repair [GO:0006283] GO:0000012; GO:0000109; GO:0000209; GO:0004842; GO:0006283; GO:0006974; GO:0006979; GO:0009411; GO:0010165; GO:0016363; GO:0031464; GO:0032991; GO:0043161; GO:0044877; GO:0045739; GO:0051865; GO:0090262; GO:0097680 41240 XM_029351643.2 119 173 108 174 172 NA NA NA NA NA NA 41241 XR_006396719.1 38 55 22 22 133 NA NA NA NA NA NA 41242 XR_006391641.1 22 28 0 16 40 NA NA NA NA NA NA 41243 XM_044320678.1 13 0 0 0 2 NA NA NA NA NA NA 41244 XM_044311430.1 0 0 161 0 42 NA NA NA NA NA NA 41245 XM_044320862.1 359 22 107 193 84 Q16720 3.79e-113 Plasma membrane calcium-transporting ATPase 3 (PMCA3) (EC 7.2.2.10) (Plasma membrane calcium ATPase isoform 3) (Plasma membrane calcium pump isoform 3) Homo sapiens (Human) calcium ion export across plasma membrane [GO:1990034]; cellular calcium ion homeostasis [GO:0006874]; ion transmembrane transport [GO:0034220]; regulation of cardiac conduction [GO:1903779]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0005388; GO:0005516; GO:0005524; GO:0005886; GO:0006874; GO:0015085; GO:0016887; GO:0019829; GO:0030165; GO:0034220; GO:0042734; GO:0043231; GO:0046872; GO:0051480; GO:0098688; GO:0098978; GO:0098982; GO:1903561; GO:1903779; GO:1905056; GO:1990032; GO:1990034 41246 XM_044320862.1 359 22 107 193 84 Q16720 5.11e-50 Plasma membrane calcium-transporting ATPase 3 (PMCA3) (EC 7.2.2.10) (Plasma membrane calcium ATPase isoform 3) (Plasma membrane calcium pump isoform 3) Homo sapiens (Human) calcium ion export across plasma membrane [GO:1990034]; cellular calcium ion homeostasis [GO:0006874]; ion transmembrane transport [GO:0034220]; regulation of cardiac conduction [GO:1903779]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0005388; GO:0005516; GO:0005524; GO:0005886; GO:0006874; GO:0015085; GO:0016887; GO:0019829; GO:0030165; GO:0034220; GO:0042734; GO:0043231; GO:0046872; GO:0051480; GO:0098688; GO:0098978; GO:0098982; GO:1903561; GO:1903779; GO:1905056; GO:1990032; GO:1990034 41247 XM_044320862.1 359 22 107 193 84 Q16720 4.18e-32 Plasma membrane calcium-transporting ATPase 3 (PMCA3) (EC 7.2.2.10) (Plasma membrane calcium ATPase isoform 3) (Plasma membrane calcium pump isoform 3) Homo sapiens (Human) calcium ion export across plasma membrane [GO:1990034]; cellular calcium ion homeostasis [GO:0006874]; ion transmembrane transport [GO:0034220]; regulation of cardiac conduction [GO:1903779]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0005388; GO:0005516; GO:0005524; GO:0005886; GO:0006874; GO:0015085; GO:0016887; GO:0019829; GO:0030165; GO:0034220; GO:0042734; GO:0043231; GO:0046872; GO:0051480; GO:0098688; GO:0098978; GO:0098982; GO:1903561; GO:1903779; GO:1905056; GO:1990032; GO:1990034 41248 XM_029323616.2 532 337 339 517 1011 P0C6Y7 2.58e-75 Histone-lysine N-methyltransferase PRDM9 (PR domain zinc finger protein 9) (PR domain-containing protein 9) (Protein-lysine N-methyltransferase PRDM9) (EC 2.1.1.-) ([histone H3]-lysine36 N-trimethyltransferase PRDM9) (EC 2.1.1.359) ([histone H3]-lysine4 N-trimethyltransferase PRDM9) (EC 2.1.1.354) ([histone H3]-lysine9 N-trimethyltransferase PRDM9) (EC 2.1.1.355) ([histone H4]-N-methyl-L-lysine20 N-methyltransferase PRDM9) (EC 2.1.1.362) ([histone H4]-lysine20 N-methyltransferase PRDM9) (EC 2.1.1.361) Rattus norvegicus (Rat) chromatin organization [GO:0006325]; double-strand break repair involved in meiotic recombination [GO:1990918]; female gamete generation [GO:0007292]; histone H3-K36 dimethylation [GO:0097676]; histone H3-K36 trimethylation [GO:0097198]; histone H3-K4 dimethylation [GO:0044648]; histone H3-K4 methylation [GO:0051568]; histone H3-K4 monomethylation [GO:0097692]; histone H3-K4 trimethylation [GO:0080182]; histone H3-K9 methylation [GO:0051567]; histone lysine methylation [GO:0034968]; histone methylation [GO:0016571]; histone modification [GO:0016570]; homologous chromosome pairing at meiosis [GO:0007129]; male gamete generation [GO:0048232]; meiosis I [GO:0007127]; meiotic gene conversion [GO:0006311]; negative regulation of apoptotic process [GO:0043066]; positive regulation of fertilization [GO:1905516]; positive regulation of histone H3-K36 trimethylation [GO:2001255]; positive regulation of meiosis I [GO:0060903]; positive regulation of reciprocal meiotic recombination [GO:0010845]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein methylation [GO:0006479]; regulation of gene expression [GO:0010468]; spermatogenesis [GO:0007283] GO:0000785; GO:0000976; GO:0005634; GO:0006311; GO:0006325; GO:0006479; GO:0007127; GO:0007129; GO:0007283; GO:0007292; GO:0010468; GO:0010844; GO:0010845; GO:0016570; GO:0016571; GO:0018024; GO:0034968; GO:0042800; GO:0042803; GO:0043066; GO:0043565; GO:0044648; GO:0045944; GO:0046872; GO:0046975; GO:0048232; GO:0051567; GO:0051568; GO:0060903; GO:0080182; GO:0097198; GO:0097676; GO:0097692; GO:0140941; GO:0140944; GO:0140949; GO:0140955; GO:1905516; GO:1990918; GO:2001255 41249 XM_029323616.2 532 337 339 517 1011 P0C6Y7 2.02e-56 Histone-lysine N-methyltransferase PRDM9 (PR domain zinc finger protein 9) (PR domain-containing protein 9) (Protein-lysine N-methyltransferase PRDM9) (EC 2.1.1.-) ([histone H3]-lysine36 N-trimethyltransferase PRDM9) (EC 2.1.1.359) ([histone H3]-lysine4 N-trimethyltransferase PRDM9) (EC 2.1.1.354) ([histone H3]-lysine9 N-trimethyltransferase PRDM9) (EC 2.1.1.355) ([histone H4]-N-methyl-L-lysine20 N-methyltransferase PRDM9) (EC 2.1.1.362) ([histone H4]-lysine20 N-methyltransferase PRDM9) (EC 2.1.1.361) Rattus norvegicus (Rat) chromatin organization [GO:0006325]; double-strand break repair involved in meiotic recombination [GO:1990918]; female gamete generation [GO:0007292]; histone H3-K36 dimethylation [GO:0097676]; histone H3-K36 trimethylation [GO:0097198]; histone H3-K4 dimethylation [GO:0044648]; histone H3-K4 methylation [GO:0051568]; histone H3-K4 monomethylation [GO:0097692]; histone H3-K4 trimethylation [GO:0080182]; histone H3-K9 methylation [GO:0051567]; histone lysine methylation [GO:0034968]; histone methylation [GO:0016571]; histone modification [GO:0016570]; homologous chromosome pairing at meiosis [GO:0007129]; male gamete generation [GO:0048232]; meiosis I [GO:0007127]; meiotic gene conversion [GO:0006311]; negative regulation of apoptotic process [GO:0043066]; positive regulation of fertilization [GO:1905516]; positive regulation of histone H3-K36 trimethylation [GO:2001255]; positive regulation of meiosis I [GO:0060903]; positive regulation of reciprocal meiotic recombination [GO:0010845]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein methylation [GO:0006479]; regulation of gene expression [GO:0010468]; spermatogenesis [GO:0007283] GO:0000785; GO:0000976; GO:0005634; GO:0006311; GO:0006325; GO:0006479; GO:0007127; GO:0007129; GO:0007283; GO:0007292; GO:0010468; GO:0010844; GO:0010845; GO:0016570; GO:0016571; GO:0018024; GO:0034968; GO:0042800; GO:0042803; GO:0043066; GO:0043565; GO:0044648; GO:0045944; GO:0046872; GO:0046975; GO:0048232; GO:0051567; GO:0051568; GO:0060903; GO:0080182; GO:0097198; GO:0097676; GO:0097692; GO:0140941; GO:0140944; GO:0140949; GO:0140955; GO:1905516; GO:1990918; GO:2001255 41250 XM_029323616.2 532 337 339 517 1011 P0C6Y7 6.67e-54 Histone-lysine N-methyltransferase PRDM9 (PR domain zinc finger protein 9) (PR domain-containing protein 9) (Protein-lysine N-methyltransferase PRDM9) (EC 2.1.1.-) ([histone H3]-lysine36 N-trimethyltransferase PRDM9) (EC 2.1.1.359) ([histone H3]-lysine4 N-trimethyltransferase PRDM9) (EC 2.1.1.354) ([histone H3]-lysine9 N-trimethyltransferase PRDM9) (EC 2.1.1.355) ([histone H4]-N-methyl-L-lysine20 N-methyltransferase PRDM9) (EC 2.1.1.362) ([histone H4]-lysine20 N-methyltransferase PRDM9) (EC 2.1.1.361) Rattus norvegicus (Rat) chromatin organization [GO:0006325]; double-strand break repair involved in meiotic recombination [GO:1990918]; female gamete generation [GO:0007292]; histone H3-K36 dimethylation [GO:0097676]; histone H3-K36 trimethylation [GO:0097198]; histone H3-K4 dimethylation [GO:0044648]; histone H3-K4 methylation [GO:0051568]; histone H3-K4 monomethylation [GO:0097692]; histone H3-K4 trimethylation [GO:0080182]; histone H3-K9 methylation [GO:0051567]; histone lysine methylation [GO:0034968]; histone methylation [GO:0016571]; histone modification [GO:0016570]; homologous chromosome pairing at meiosis [GO:0007129]; male gamete generation [GO:0048232]; meiosis I [GO:0007127]; meiotic gene conversion [GO:0006311]; negative regulation of apoptotic process [GO:0043066]; positive regulation of fertilization [GO:1905516]; positive regulation of histone H3-K36 trimethylation [GO:2001255]; positive regulation of meiosis I [GO:0060903]; positive regulation of reciprocal meiotic recombination [GO:0010845]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein methylation [GO:0006479]; regulation of gene expression [GO:0010468]; spermatogenesis [GO:0007283] GO:0000785; GO:0000976; GO:0005634; GO:0006311; GO:0006325; GO:0006479; GO:0007127; GO:0007129; GO:0007283; GO:0007292; GO:0010468; GO:0010844; GO:0010845; GO:0016570; GO:0016571; GO:0018024; GO:0034968; GO:0042800; GO:0042803; GO:0043066; GO:0043565; GO:0044648; GO:0045944; GO:0046872; GO:0046975; GO:0048232; GO:0051567; GO:0051568; GO:0060903; GO:0080182; GO:0097198; GO:0097676; GO:0097692; GO:0140941; GO:0140944; GO:0140949; GO:0140955; GO:1905516; GO:1990918; GO:2001255 41251 XR_006391505.1 86 63 73 150 243 NA NA NA NA NA NA 41252 XM_044316590.1 31 25 8 45 40 NA NA NA NA NA NA 41253 XM_029324822.2 374 517 412 402 632 F6QEU4 1.38e-29 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 41254 XM_044307916.1 198 0 0 414 66 P0CT40 1.54e-73 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 41255 XR_006395159.1 130 80 41 68 69 NA NA NA NA NA NA 41256 XM_029326869.2 0 0 28 34 13 O54853 3.24e-147 Potassium voltage-gated channel subfamily H member 6 (Ether-a-go-go-related gene potassium channel 2) (ERG-2) (Eag-related protein 2) (Ether-a-go-go-related protein 2) (Voltage-gated potassium channel subunit Kv11.2) Rattus norvegicus (Rat) membrane repolarization during action potential [GO:0086011]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307] GO:0005242; GO:0005249; GO:0005267; GO:0005886; GO:0006813; GO:0034765; GO:0042391; GO:0044877; GO:0060307; GO:0071805; GO:0086011; GO:0086091 41257 XM_029338607.2 1517 1594 886 1081 1286 NA NA NA NA NA NA 41258 XR_006393301.1 21 31 3 36 10 NA NA NA NA NA NA 41259 XM_029344829.2 125 137 117 173 197 NA NA NA NA NA NA 41260 XM_044315585.1 78 0 12 21 48 NA NA NA NA NA NA 41261 XM_029349624.2 11 0 11 2 45 NA NA NA NA NA NA 41262 XM_044318597.1 39 10 0 0 74 NA NA NA NA NA NA 41263 XR_006395842.1 22 11 24 3 28 NA NA NA NA NA NA 41264 XM_029342299.2 1465 492 475 888 553 Q5F364 0 Multidrug resistance-associated protein 1 (EC 7.6.2.2) (ATP-binding cassette sub-family C member 1) (Glutathione-S-conjugate-translocating ATPase ABCC1) (EC 7.6.2.3) (Leukotriene C(4) transporter) (LTC4 transporter) Gallus gallus (Chicken) glutathione transmembrane transport [GO:0034775]; lipid transport [GO:0006869]; transmembrane transport [GO:0055085]; xenobiotic transport [GO:0042908] GO:0005524; GO:0006869; GO:0008559; GO:0016020; GO:0016323; GO:0016887; GO:0034634; GO:0034775; GO:0042626; GO:0042908; GO:0055085 41265 XM_044327296.1 91 261 71 132 214 NA NA NA NA NA NA 41266 XM_044313947.1 6 0 0 0 19 B8VIU6 3.55e-61 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 41267 XM_029347785.2 279 720 144 98 93 P51824 1.01e-64 ADP-ribosylation factor 1 (EC 3.6.5.2) Solanum tuberosum (Potato) intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192] GO:0003924; GO:0005525; GO:0005737; GO:0005794; GO:0006886; GO:0016192 41268 XM_044307005.1 2 0 0 9 0 NA NA NA NA NA NA 41269 XM_029331797.2 416 270 230 342 411 Q3UIK4 5.01e-172 N6-adenosine-methyltransferase non-catalytic subunit (Methyltransferase-like protein 14) Mus musculus (Mouse) forebrain radial glial cell differentiation [GO:0021861]; gliogenesis [GO:0042063]; mRNA catabolic process [GO:0006402]; mRNA destabilization [GO:0061157]; mRNA methylation [GO:0080009]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of hematopoietic progenitor cell differentiation [GO:1901533]; positive regulation of translation [GO:0045727]; RNA methylation [GO:0001510]; spermatogenesis [GO:0007283]; stem cell population maintenance [GO:0019827] GO:0000398; GO:0001510; GO:0003729; GO:0005634; GO:0005654; GO:0006402; GO:0007283; GO:0016422; GO:0019827; GO:0021861; GO:0036396; GO:0042063; GO:0045727; GO:0061157; GO:0080009; GO:1901533 41270 XM_029347284.2 308 404 323 218 151 NA NA NA NA NA NA 41271 XR_006393812.1 11 0 0 3 1 NA NA NA NA NA NA 41272 XM_044324999.1 28 0 2 32 0 Q96AY4 9.46e-46 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41273 XM_044324999.1 28 0 2 32 0 Q96AY4 1.89e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41274 XM_044324999.1 28 0 2 32 0 Q96AY4 2.33e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41275 XM_044324999.1 28 0 2 32 0 Q96AY4 4e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41276 XM_044324999.1 28 0 2 32 0 Q96AY4 4.69e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41277 XM_044324999.1 28 0 2 32 0 Q96AY4 5.12e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41278 XM_044324999.1 28 0 2 32 0 Q96AY4 4.91e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41279 XM_044324999.1 28 0 2 32 0 Q96AY4 5.78e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41280 XM_044324999.1 28 0 2 32 0 Q96AY4 3.08e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41281 XM_044324999.1 28 0 2 32 0 Q96AY4 4.29e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41282 XM_044324999.1 28 0 2 32 0 Q96AY4 1.38e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41283 XM_044324999.1 28 0 2 32 0 Q96AY4 5.12e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41284 XM_029335736.2 0 2 3 12 2 Q2KIP6 1.18e-22 Kappa-type opioid receptor (K-OR-1) (KOR-1) Bos taurus (Bovine) adenylate cyclase-inhibiting opioid receptor signaling pathway [GO:0031635]; defense response to virus [GO:0051607]; G protein-coupled opioid receptor signaling pathway [GO:0038003]; immune response [GO:0006955]; locomotory behavior [GO:0007626]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; regulation of saliva secretion [GO:0046877]; sensory perception of pain [GO:0019233] GO:0004930; GO:0004985; GO:0005654; GO:0005829; GO:0005886; GO:0006955; GO:0007200; GO:0007218; GO:0007626; GO:0016020; GO:0019233; GO:0031635; GO:0038003; GO:0038048; GO:0042277; GO:0042923; GO:0043005; GO:0046877; GO:0051607 41285 XM_029335755.2 0 0 79 181 34 O62809 1.54e-33 Orexin receptor type 2 (Ox-2-R) (Ox2-R) (Ox2R) (Hypocretin receptor type 2) Sus scrofa (Pig) circadian sleep/wake cycle process [GO:0022410]; feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; locomotion [GO:0040011]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; regulation of circadian sleep/wake cycle, wakefulness [GO:0010840]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0004930; GO:0005886; GO:0007186; GO:0007200; GO:0007218; GO:0007631; GO:0010840; GO:0016499; GO:0022410; GO:0040011; GO:0051480 41286 XR_006397358.1 21 11 7 49 10 NA NA NA NA NA NA 41287 XM_029324629.2 111 77 67 137 0 NA NA NA NA NA NA 41288 XM_044324063.1 141 119 70 173 78 NA NA NA NA NA NA 41289 XM_029323421.2 933 1124 404 926 491 Q3ZCL5 1.27e-87 Arfaptin-2 (ADP-ribosylation factor-interacting protein 2) Bos taurus (Bovine) intracellular protein transport [GO:0006886]; mitophagy [GO:0000423]; protein localization to phagophore assembly site [GO:0034497]; regulation of Arp2/3 complex-mediated actin nucleation [GO:0034315] GO:0000423; GO:0005543; GO:0006886; GO:0019904; GO:0032588; GO:0034315; GO:0034497 41290 XM_029328030.2 129 88 38 52 90 NA NA NA NA NA NA 41291 XM_029335415.2 1706 784 809 1308 1441 Q8R081 9.07e-53 Heterogeneous nuclear ribonucleoprotein L (hnRNP L) Mus musculus (Mouse) mRNA processing [GO:0006397]; negative regulation of DNA-templated transcription [GO:0045892]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of RNA splicing [GO:0043484] GO:0000381; GO:0000785; GO:0000976; GO:0003723; GO:0003729; GO:0003730; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006397; GO:0035770; GO:0043484; GO:0045120; GO:0045202; GO:0045892; GO:0048471; GO:0097157; GO:1990715; GO:1990904 41292 XM_029335415.2 1706 784 809 1308 1441 Q8R081 1.9e-52 Heterogeneous nuclear ribonucleoprotein L (hnRNP L) Mus musculus (Mouse) mRNA processing [GO:0006397]; negative regulation of DNA-templated transcription [GO:0045892]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of RNA splicing [GO:0043484] GO:0000381; GO:0000785; GO:0000976; GO:0003723; GO:0003729; GO:0003730; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006397; GO:0035770; GO:0043484; GO:0045120; GO:0045202; GO:0045892; GO:0048471; GO:0097157; GO:1990715; GO:1990904 41293 XM_029334924.2 186 62 70 53 141 NA NA NA NA NA NA 41294 XM_029358243.2 964 547 490 724 870 Q8BNQ3 2.14e-47 Integral membrane protein GPR137B (Transmembrane 7 superfamily member 1 protein) Mus musculus (Mouse) autophagy [GO:0006914]; negative regulation of bone resorption [GO:0045779]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of protein localization to lysosome [GO:0150032]; positive regulation of TORC1 signaling [GO:1904263]; regulation of autophagy [GO:0010506]; regulation of GTPase activity [GO:0043087]; regulation of macrophage activation [GO:0043030] GO:0005765; GO:0006914; GO:0010506; GO:0043030; GO:0043087; GO:0045671; GO:0045779; GO:0150032; GO:1904263 41295 XM_029330954.2 502 205 237 377 218 NA NA NA NA NA NA 41296 XM_029329295.2 1992 1736 791 1499 1392 P63326 2.31e-57 40S ribosomal protein S10 Rattus norvegicus (Rat) ribosomal small subunit assembly [GO:0000028] GO:0000028; GO:0000049; GO:0003723; GO:0003735; GO:0005730; GO:0022626; GO:0022627; GO:0045202 41297 XR_006394359.1 0 38 8 9 22 NA NA NA NA NA NA 41298 XM_044312208.1 545 828 592 1089 1016 Q96AY4 1.83e-98 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41299 XM_044312208.1 545 828 592 1089 1016 Q96AY4 5.86e-98 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41300 XM_044312208.1 545 828 592 1089 1016 Q96AY4 1.56e-97 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41301 XM_044312208.1 545 828 592 1089 1016 Q96AY4 1.94e-96 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41302 XM_044312208.1 545 828 592 1089 1016 Q96AY4 1.68e-95 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41303 XM_044312208.1 545 828 592 1089 1016 Q96AY4 4.72e-95 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41304 XM_044312208.1 545 828 592 1089 1016 Q96AY4 2.46e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41305 XM_044312208.1 545 828 592 1089 1016 Q96AY4 7.71e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41306 XM_044310377.1 8 4 0 0 5 NA NA NA NA NA NA 41307 XM_029330047.2 720 449 292 245 516 Q504N0 8.91e-107 Carboxypeptidase A2 (EC 3.4.17.15) Mus musculus (Mouse) proteolysis [GO:0006508] GO:0004180; GO:0004181; GO:0005576; GO:0005615; GO:0006508; GO:0008270 41308 XM_044314661.1 0 0 0 0 9 NA NA NA NA NA NA 41309 XM_029339636.2 89 0 53 0 0 Q75W95 1.2e-42 NK1 transcription factor-related protein 1 (Homeodomain protein Sax2) (NK1 transcription factor related 2-like,b) Danio rerio (Zebrafish) (Brachydanio rerio) cell differentiation [GO:0030154]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0030154 41310 XR_006394515.1 108 53 24 32 72 NA NA NA NA NA NA 41311 XR_006395825.1 0 0 0 0 11 NA NA NA NA NA NA 41312 XM_044307830.1 294 113 165 195 286 Q7RTR2 3.45e-61 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 41313 XM_044307830.1 294 113 165 195 286 Q7RTR2 5e-61 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 41314 XM_044307830.1 294 113 165 195 286 Q7RTR2 9.5e-53 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 41315 XM_044307830.1 294 113 165 195 286 Q7RTR2 4.3e-51 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 41316 XR_006393393.1 17 251 104 2 109 NA NA NA NA NA NA 41317 XM_044313854.1 0 52 50 121 39 NA NA NA NA NA NA 41318 XR_006395195.1 59 25 4 0 19 NA NA NA NA NA NA 41319 XM_044308386.1 0 47 0 73 0 E7FAM5 8.86e-59 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 41320 XM_044328176.1 188 0 259 0 1080 P50430 2.33e-131 Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S) Rattus norvegicus (Rat) anterior head development [GO:0097065]; autophagy [GO:0006914]; central nervous system development [GO:0007417]; colon epithelial cell migration [GO:0061580]; dermatan sulfate catabolic process [GO:0030209]; positive regulation of neuron projection development [GO:0010976]; regulation of epithelial cell migration [GO:0010632]; response to estrogen [GO:0043627]; response to methylmercury [GO:0051597]; response to nutrient [GO:0007584]; response to pH [GO:0009268] GO:0003943; GO:0004065; GO:0005739; GO:0005764; GO:0005791; GO:0005794; GO:0006914; GO:0007417; GO:0007584; GO:0008484; GO:0009268; GO:0009986; GO:0010632; GO:0010976; GO:0030209; GO:0043627; GO:0043890; GO:0046872; GO:0051597; GO:0061580; GO:0097065 41321 XM_044325937.1 1704 1305 1091 1681 1478 P79896 0 Alcohol dehydrogenase class-3 (EC 1.1.1.1) (Alcohol dehydrogenase class-III) (Glutathione-dependent formaldehyde dehydrogenase) (FALDH) (FDH) (GSH-FDH) (EC 1.1.1.-) (S-(hydroxymethyl)glutathione dehydrogenase) (EC 1.1.1.284) Sparus aurata (Gilthead sea bream) ethanol oxidation [GO:0006069] GO:0004022; GO:0005737; GO:0006069; GO:0008270; GO:0106321; GO:0106322 41322 XM_044312118.1 115 0 201 0 89 Q6ZNA5 4.58e-44 Ferric-chelate reductase 1 (EC 1.-.-.-) (Stromal cell-derived receptor 2) (SDR-2) Homo sapiens (Human) cellular iron ion homeostasis [GO:0006879] GO:0006879; GO:0016020; GO:0016722; GO:0046872 41323 XR_006393226.1 21 2 16 5 0 NA NA NA NA NA NA 41324 XM_044319865.1 11 9 7 9 11 NA NA NA NA NA NA 41325 XM_044309235.1 6 16 13 55 14 O64411 3.53e-62 Polyamine oxidase 1 (EC 1.5.3.14) (EC 1.5.3.15) Zea mays (Maize) polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208] GO:0006598; GO:0009505; GO:0016491; GO:0046208; GO:0046592; GO:0048046; GO:0050660; GO:0052893; GO:0052896; GO:0052897; GO:0052900 41326 XR_006396413.1 2 4 31 10 8 NA NA NA NA NA NA 41327 XM_044310404.1 8 0 16 0 16 Q9FT72 3.95e-34 ATP-dependent DNA helicase Q-like 3 (EC 3.6.4.12) (RecQ-like protein 3) (AtRecQ3) (AtRecQl3) Arabidopsis thaliana (Mouse-ear cress) DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724] GO:0000724; GO:0004386; GO:0005524; GO:0005634; GO:0005694; GO:0005737; GO:0006268; GO:0006281; GO:0006310; GO:0009378; GO:0016887; GO:0032508; GO:0043138; GO:0046872; GO:1990814 41328 XM_044318462.1 0 0 10 2 40 NA NA NA NA NA NA 41329 XM_044319053.1 3118 2037 2317 3528 2475 B3EWZ5 8.49e-74 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 41330 XM_044319053.1 3118 2037 2317 3528 2475 B3EWZ5 1.71e-72 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 41331 XM_044319053.1 3118 2037 2317 3528 2475 B3EWZ5 7.89e-63 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 41332 XM_044319053.1 3118 2037 2317 3528 2475 B3EWZ5 1.53e-55 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 41333 XM_044319053.1 3118 2037 2317 3528 2475 B3EWZ5 2.7e-55 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 41334 XM_044319053.1 3118 2037 2317 3528 2475 B3EWZ5 2.77e-55 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 41335 XM_044319053.1 3118 2037 2317 3528 2475 B3EWZ5 2.73e-49 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 41336 XM_044319053.1 3118 2037 2317 3528 2475 B3EWZ5 5.3e-49 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 41337 XM_044319053.1 3118 2037 2317 3528 2475 B3EWZ5 5.87e-47 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 41338 XM_044319053.1 3118 2037 2317 3528 2475 B3EWZ5 6.66e-45 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 41339 XM_044319053.1 3118 2037 2317 3528 2475 B3EWZ5 1.61e-44 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 41340 XM_044319053.1 3118 2037 2317 3528 2475 B3EWZ5 2.8e-42 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 41341 XM_044319053.1 3118 2037 2317 3528 2475 B3EWZ5 2.55e-41 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 41342 XM_044319053.1 3118 2037 2317 3528 2475 B3EWZ5 1.15e-40 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 41343 XM_044319053.1 3118 2037 2317 3528 2475 B3EWZ5 1.62e-40 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 41344 XM_044319053.1 3118 2037 2317 3528 2475 B3EWZ5 1.92e-40 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 41345 XM_044319053.1 3118 2037 2317 3528 2475 B3EWZ5 8.76e-39 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 41346 XM_044319053.1 3118 2037 2317 3528 2475 B3EWZ5 1.16e-38 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 41347 XM_044319053.1 3118 2037 2317 3528 2475 B3EWZ5 1.98e-38 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 41348 XM_044319053.1 3118 2037 2317 3528 2475 B3EWZ5 1.14e-36 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 41349 XM_044319053.1 3118 2037 2317 3528 2475 B3EWZ5 2.41e-35 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 41350 XM_044319053.1 3118 2037 2317 3528 2475 B3EWZ5 1.14e-33 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 41351 XM_044319053.1 3118 2037 2317 3528 2475 B3EWZ5 1.59e-33 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 41352 XM_044319053.1 3118 2037 2317 3528 2475 B3EWZ5 8.43e-31 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 41353 XM_044319053.1 3118 2037 2317 3528 2475 B3EWZ5 9.15e-30 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 41354 XM_044319053.1 3118 2037 2317 3528 2475 B3EWZ5 3.08e-28 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 41355 XM_044319053.1 3118 2037 2317 3528 2475 B3EWZ5 4.5e-28 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 41356 XM_044319053.1 3118 2037 2317 3528 2475 B3EWZ5 6.85e-28 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 41357 XM_044319053.1 3118 2037 2317 3528 2475 B3EWZ5 1.41e-27 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 41358 XM_044319053.1 3118 2037 2317 3528 2475 B3EWZ5 3.05e-27 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 41359 XM_044319053.1 3118 2037 2317 3528 2475 B3EWZ5 7.81e-27 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 41360 XM_044319053.1 3118 2037 2317 3528 2475 B3EWZ5 3.72e-26 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 41361 XM_044319053.1 3118 2037 2317 3528 2475 B3EWZ5 6.11e-26 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 41362 XM_044319053.1 3118 2037 2317 3528 2475 B3EWZ5 6.42e-26 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 41363 XM_044319053.1 3118 2037 2317 3528 2475 B3EWZ5 2.28e-25 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 41364 XM_044319053.1 3118 2037 2317 3528 2475 B3EWZ5 3.71e-25 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 41365 XM_044319053.1 3118 2037 2317 3528 2475 B3EWZ5 1.14e-24 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 41366 XM_044319053.1 3118 2037 2317 3528 2475 B3EWZ5 8.79e-24 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 41367 XM_029339061.2 3675 4160 1956 2898 2876 NA NA NA NA NA NA 41368 XR_006393139.1 0 0 0 6907 0 NA NA NA NA NA NA 41369 XM_044325744.1 186 143 146 112 33 O08795 3.53e-25 Glucosidase 2 subunit beta (80K-H protein) (Glucosidase II subunit beta) (Protein kinase C substrate 60.1 kDa protein heavy chain) (PKCSH) Mus musculus (Mouse) in utero embryonic development [GO:0001701]; liver development [GO:0001889]; N-glycan processing [GO:0006491]; negative regulation of neuron projection development [GO:0010977]; nitrogen compound metabolic process [GO:0006807] GO:0001701; GO:0001889; GO:0003723; GO:0005080; GO:0005509; GO:0005783; GO:0006491; GO:0006807; GO:0010977; GO:0017177; GO:0043231; GO:0044325; GO:0044877; GO:0051219 41370 XM_029326907.2 679 451 351 588 654 A0A1D5NSM8 1.91e-37 NA NA NA NA 41371 XM_044322313.1 277 294 198 515 628 NA NA NA NA NA NA 41372 XM_044326340.1 41 17 12 82 8 A4IFK2 8.62e-94 Solute carrier family 35 member E3 Bos taurus (Bovine) NA GO:0005338; GO:0005794; GO:0015297; GO:0016020 41373 XM_044324517.1 172 184 159 172 167 P18887 5.15e-60 DNA repair protein XRCC1 (X-ray repair cross-complementing protein 1) Homo sapiens (Human) base-excision repair [GO:0006284]; cerebellum morphogenesis [GO:0021587]; double-strand break repair via nonhomologous end joining [GO:0006303]; hippocampus development [GO:0021766]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of protein ADP-ribosylation [GO:0010836]; positive regulation of DNA ligase activity [GO:1904877]; positive regulation of single strand break repair [GO:1903518]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to organic substance [GO:0010033]; response to xenobiotic stimulus [GO:0009410]; single strand break repair [GO:0000012]; telomeric DNA-containing double minutes formation [GO:0061819]; voluntary musculoskeletal movement [GO:0050882] GO:0000012; GO:0000781; GO:0000785; GO:0001666; GO:0005634; GO:0005654; GO:0005730; GO:0006284; GO:0006303; GO:0009410; GO:0010033; GO:0010836; GO:0019899; GO:0021587; GO:0021766; GO:0032356; GO:0033194; GO:0050882; GO:0061819; GO:0070522; GO:0072572; GO:0090734; GO:1903518; GO:1904877; GO:1905765; GO:1990414; GO:1990599 41374 XM_044324517.1 172 184 159 172 167 P18887 4.94e-49 DNA repair protein XRCC1 (X-ray repair cross-complementing protein 1) Homo sapiens (Human) base-excision repair [GO:0006284]; cerebellum morphogenesis [GO:0021587]; double-strand break repair via nonhomologous end joining [GO:0006303]; hippocampus development [GO:0021766]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of protein ADP-ribosylation [GO:0010836]; positive regulation of DNA ligase activity [GO:1904877]; positive regulation of single strand break repair [GO:1903518]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to organic substance [GO:0010033]; response to xenobiotic stimulus [GO:0009410]; single strand break repair [GO:0000012]; telomeric DNA-containing double minutes formation [GO:0061819]; voluntary musculoskeletal movement [GO:0050882] GO:0000012; GO:0000781; GO:0000785; GO:0001666; GO:0005634; GO:0005654; GO:0005730; GO:0006284; GO:0006303; GO:0009410; GO:0010033; GO:0010836; GO:0019899; GO:0021587; GO:0021766; GO:0032356; GO:0033194; GO:0050882; GO:0061819; GO:0070522; GO:0072572; GO:0090734; GO:1903518; GO:1904877; GO:1905765; GO:1990414; GO:1990599 41375 XR_006397660.1 0 57 0 0 3 NA NA NA NA NA NA 41376 XR_006391446.1 0 0 0 8 0 NA NA NA NA NA NA 41377 XM_044308954.1 177 141 152 114 128 NA NA NA NA NA NA 41378 XM_029332816.2 250 129 115 97 138 Q8BYI9 1.01e-71 Tenascin-R (TN-R) (Janusin) (Neural recognition molecule J1-160/180) (Restrictin) Mus musculus (Mouse) associative learning [GO:0008306]; axon extension [GO:0048675]; axon extension involved in regeneration [GO:0048677]; cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198]; locomotory exploration behavior [GO:0035641]; long-term synaptic potentiation [GO:0060291]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of axon extension [GO:0030517]; negative regulation of axon extension involved in regeneration [GO:0048692]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of neuron projection development [GO:0010977]; negative regulation of synaptic transmission [GO:0050805]; neuroblast migration [GO:0097402]; neuromuscular process controlling balance [GO:0050885]; neuron cell-cell adhesion [GO:0007158]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transmission of nerve impulse [GO:0051971]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of cell migration [GO:0030334]; synapse organization [GO:0050808]; synaptic transmission, glutamatergic [GO:0035249]; telencephalon cell migration [GO:0022029] GO:0005102; GO:0005178; GO:0005615; GO:0007155; GO:0007158; GO:0007162; GO:0008306; GO:0009986; GO:0010977; GO:0022029; GO:0022408; GO:0030155; GO:0030198; GO:0030334; GO:0030517; GO:0031012; GO:0035249; GO:0035641; GO:0045121; GO:0045595; GO:0046625; GO:0048675; GO:0048677; GO:0048692; GO:0050804; GO:0050805; GO:0050808; GO:0050885; GO:0051968; GO:0051971; GO:0060291; GO:0062023; GO:0072534; GO:0090733; GO:0097402; GO:0098685; GO:0098686; GO:0098965; GO:0098966; GO:0098978 41379 XM_029349802.2 923 898 602 401 746 NA NA NA NA NA NA 41380 XM_029350626.2 202 203 63 153 104 NA NA NA NA NA NA 41381 XM_029325676.2 10 23 18 8 9 NA NA NA NA NA NA 41382 XM_044322715.1 18 0 12 1 32 NA NA NA NA NA NA 41383 XM_044326815.1 24 6 0 10 13 NA NA NA NA NA NA 41384 XR_006397237.1 0 98 0 0 0 NA NA NA NA NA NA 41385 XM_029329868.2 1 953 0 136 0 P20072 4.18e-70 Annexin A7 (Annexin VII) (Annexin-7) (Synexin) Bos taurus (Bovine) NA GO:0005509; GO:0005544; GO:0005634; GO:0005737; GO:0042584 41386 XM_029333697.2 335 127 163 119 205 NA NA NA NA NA NA 41387 XM_029341954.2 488 434 276 374 419 Q9D6L8 1.66e-84 Peptidyl-prolyl cis-trans isomerase-like 3 (PPIase) (EC 5.2.1.8) (CYP10L) (Cyclophilin-like protein PPIL3) (Rotamase PPIL3) Mus musculus (Mouse) mRNA processing [GO:0006397]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; RNA splicing [GO:0008380] GO:0000413; GO:0003755; GO:0006397; GO:0006457; GO:0008380; GO:0071013 41388 XM_044324160.1 34 12 1 2 0 NA NA NA NA NA NA 41389 XM_029356919.2 59 54 9 28 123 NA NA NA NA NA NA 41390 XM_029337156.2 787 391 454 761 1018 Q8TAQ2 1.55e-172 SWI/SNF complex subunit SMARCC2 (BRG1-associated factor 170) (BAF170) (SWI/SNF complex 170 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2) Homo sapiens (Human) chromatin remodeling [GO:0006338]; negative regulation of DNA-templated transcription [GO:0045892]; nervous system development [GO:0007399]; nucleosome disassembly [GO:0006337]; positive regulation of cell differentiation [GO:0045597]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of T cell differentiation [GO:0045582]; regulation of G0 to G1 transition [GO:0070316]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of nucleotide-excision repair [GO:2000819]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000776; GO:0000785; GO:0003713; GO:0005654; GO:0006337; GO:0006338; GO:0006357; GO:0007399; GO:0016363; GO:0016514; GO:0016586; GO:0030071; GO:0032991; GO:0035060; GO:0042393; GO:0045582; GO:0045597; GO:0045663; GO:0045892; GO:0045893; GO:0070316; GO:0071564; GO:0071565; GO:0140092; GO:2000045; GO:2000781; GO:2000819 41391 XM_029337156.2 787 391 454 761 1018 Q8TAQ2 4.93e-86 SWI/SNF complex subunit SMARCC2 (BRG1-associated factor 170) (BAF170) (SWI/SNF complex 170 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2) Homo sapiens (Human) chromatin remodeling [GO:0006338]; negative regulation of DNA-templated transcription [GO:0045892]; nervous system development [GO:0007399]; nucleosome disassembly [GO:0006337]; positive regulation of cell differentiation [GO:0045597]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of T cell differentiation [GO:0045582]; regulation of G0 to G1 transition [GO:0070316]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of nucleotide-excision repair [GO:2000819]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000776; GO:0000785; GO:0003713; GO:0005654; GO:0006337; GO:0006338; GO:0006357; GO:0007399; GO:0016363; GO:0016514; GO:0016586; GO:0030071; GO:0032991; GO:0035060; GO:0042393; GO:0045582; GO:0045597; GO:0045663; GO:0045892; GO:0045893; GO:0070316; GO:0071564; GO:0071565; GO:0140092; GO:2000045; GO:2000781; GO:2000819 41392 XM_029325830.2 0 9 72 0 0 NA NA NA NA NA NA 41393 XM_044309745.1 0 0 19 0 4 NA NA NA NA NA NA 41394 XM_029345935.2 179 59 127 152 306 O15439 0 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 41395 XM_044308749.1 55 7 42 10 58 NA NA NA NA NA NA 41396 XM_029350220.2 0 76 0 173 0 Q9R0Z9 2e-160 Rho GTPase-activating protein 7 (Deleted in liver cancer 1 protein homolog) (DLC-1) (Rho-type GTPase-activating protein 7) (START domain-containing protein 12) (StARD12) (StAR-related lipid transfer protein 12) Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of phospholipase C activity [GO:0007202]; apoptotic process [GO:0006915]; cytoskeleton organization [GO:0007010]; focal adhesion assembly [GO:0048041]; forebrain development [GO:0030900]; heart morphogenesis [GO:0003007]; hindbrain morphogenesis [GO:0021575]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of stress fiber assembly [GO:0051497]; neural tube closure [GO:0001843]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; regulation of Rho protein signal transduction [GO:0035023]; signal transduction [GO:0007165] GO:0001725; GO:0001843; GO:0003007; GO:0005096; GO:0005634; GO:0005737; GO:0005829; GO:0005884; GO:0005901; GO:0005925; GO:0006915; GO:0006919; GO:0007010; GO:0007165; GO:0007202; GO:0008285; GO:0008289; GO:0008360; GO:0017166; GO:0021575; GO:0030036; GO:0030336; GO:0030864; GO:0030900; GO:0032587; GO:0032956; GO:0035023; GO:0035024; GO:0035307; GO:0042169; GO:0043274; GO:0045121; GO:0048041; GO:0051497; GO:0051895; GO:1900119 41397 XM_029350220.2 0 76 0 173 0 Q9R0Z9 5.43e-24 Rho GTPase-activating protein 7 (Deleted in liver cancer 1 protein homolog) (DLC-1) (Rho-type GTPase-activating protein 7) (START domain-containing protein 12) (StARD12) (StAR-related lipid transfer protein 12) Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of phospholipase C activity [GO:0007202]; apoptotic process [GO:0006915]; cytoskeleton organization [GO:0007010]; focal adhesion assembly [GO:0048041]; forebrain development [GO:0030900]; heart morphogenesis [GO:0003007]; hindbrain morphogenesis [GO:0021575]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of stress fiber assembly [GO:0051497]; neural tube closure [GO:0001843]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; regulation of Rho protein signal transduction [GO:0035023]; signal transduction [GO:0007165] GO:0001725; GO:0001843; GO:0003007; GO:0005096; GO:0005634; GO:0005737; GO:0005829; GO:0005884; GO:0005901; GO:0005925; GO:0006915; GO:0006919; GO:0007010; GO:0007165; GO:0007202; GO:0008285; GO:0008289; GO:0008360; GO:0017166; GO:0021575; GO:0030036; GO:0030336; GO:0030864; GO:0030900; GO:0032587; GO:0032956; GO:0035023; GO:0035024; GO:0035307; GO:0042169; GO:0043274; GO:0045121; GO:0048041; GO:0051497; GO:0051895; GO:1900119 41398 XM_029344701.2 0 0 2 4 8 P30974 3.83e-30 Tachykinin-like peptides receptor 86C (NKD) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; inter-male aggressive behavior [GO:0002121]; neuropeptide signaling pathway [GO:0007218]; tachykinin receptor signaling pathway [GO:0007217] GO:0002121; GO:0004995; GO:0005886; GO:0007186; GO:0007217; GO:0007218; GO:0008188; GO:0016020 41399 XR_006392940.1 41 2 25 5 151 NA NA NA NA NA NA 41400 XM_029334131.2 258 122 245 521 0 NA NA NA NA NA NA 41401 XR_006398187.1 0 45 13 22 19 NA NA NA NA NA NA 41402 XR_003825706.2 5 1 7 4 6 NA NA NA NA NA NA 41403 XM_044309636.1 473 348 222 246 231 NA NA NA NA NA NA 41404 XM_029336365.2 524 379 207 401 629 O15254 0 Peroxisomal acyl-coenzyme A oxidase 3 (EC 1.3.3.6) (Branched-chain acyl-CoA oxidase) (BRCACox) (Pristanoyl-CoA oxidase) Homo sapiens (Human) fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; lipid homeostasis [GO:0055088] GO:0003997; GO:0005504; GO:0005777; GO:0005782; GO:0005829; GO:0016020; GO:0016402; GO:0033540; GO:0050660; GO:0055088; GO:0071949 41405 XR_006398201.1 605 599 533 1132 779 NA NA NA NA NA NA 41406 XR_003824866.2 49 21 47 27 48 NA NA NA NA NA NA 41407 XM_044310882.1 178 15 76 5 111 NA NA NA NA NA NA 41408 XM_044313241.1 519 332 314 585 597 P18460 2.86e-77 Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (Tyrosine kinase receptor CEK2) Gallus gallus (Chicken) apoptotic process [GO:0006915]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0004714; GO:0005007; GO:0005524; GO:0005886; GO:0006915; GO:0007169; GO:0008284; GO:0017134; GO:0033674; GO:0043235; GO:0043410 41409 XM_044314558.1 7 0 0 0 0 Q96DM1 1.88e-63 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 41410 XM_044319234.1 9 71 24 35 4 NA NA NA NA NA NA 41411 XM_044325572.1 0 0 57 0 0 NA NA NA NA NA NA 41412 XM_044327615.1 75 15 6 0 5 NA NA NA NA NA NA 41413 XR_006395356.1 42 85 67 89 33 NA NA NA NA NA NA 41414 XM_029339465.2 1138 1172 467 1144 1104 A7RWP6 0 Eukaryotic translation initiation factor 3 subunit E (eIF3e) (Eukaryotic translation initiation factor 3 subunit 6) Nematostella vectensis (Starlet sea anemone) formation of cytoplasmic translation initiation complex [GO:0001732]; translational initiation [GO:0006413] GO:0001732; GO:0003743; GO:0005634; GO:0005852; GO:0006413; GO:0016282; GO:0033290; GO:0071540 41415 XM_044328031.1 45 17 26 28 23 Q90678 2.43e-76 Platelet-activating factor acetylhydrolase (PAF acetylhydrolase) (EC 3.1.1.47) (1-alkyl-2-acetylglycerophosphocholine esterase) (2-acetyl-1-alkylglycerophosphocholine esterase) (LDL-associated phospholipase A2) (LDL-PLA(2)) (PAF 2-acylhydrolase) Gallus gallus (Chicken) lipid catabolic process [GO:0016042] GO:0003847; GO:0005615; GO:0016042 41416 XM_029339505.2 35 0 0 0 0 NA NA NA NA NA NA 41417 XM_044321613.1 29 22 7 8 60 P59046 9.99e-56 NACHT, LRR and PYD domains-containing protein 12 (Monarch-1) (PYRIN-containing APAF1-like protein 7) (Regulated by nitric oxide) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cellular response to cytokine stimulus [GO:0071345]; dendritic cell migration [GO:0036336]; ERK1 and ERK2 cascade [GO:0070371]; negative regulation of cytokine production [GO:0001818]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of signal transduction [GO:0009968]; negative regulation of Toll signaling pathway [GO:0045751]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of inflammatory response [GO:0050727]; regulation of interleukin-18 production [GO:0032661]; signal transduction [GO:0007165] GO:0001818; GO:0005524; GO:0005737; GO:0005829; GO:0006919; GO:0007165; GO:0008656; GO:0009968; GO:0031953; GO:0032088; GO:0032661; GO:0032692; GO:0032715; GO:0032731; GO:0036336; GO:0038061; GO:0043122; GO:0043124; GO:0043281; GO:0045345; GO:0045751; GO:0050727; GO:0050728; GO:0050729; GO:0070371; GO:0070373; GO:0071345; GO:1901223; GO:1901224 41418 XR_003825344.2 2 7 9 15 17 NA NA NA NA NA NA 41419 XM_029340289.2 9 182 198 160 231 Q9UKJ3 4.63e-36 G patch domain-containing protein 8 Homo sapiens (Human) NA GO:0003723; GO:0005634; GO:0046872 41420 XM_044314579.1 1863 145 36 190 55 Q6A198 1.14e-23 Alpha-(1,3)-fucosyltransferase 10 (EC 2.4.1.-) (Fucosyltransferase X) (Fuc-TX) (FucT-X) (Galactoside 3-L-fucosyltransferase 10) (Fucosyltransferase 10) Bos taurus (Bovine) fucosylation [GO:0036065]; N-glycan fucosylation [GO:0036071]; protein glycosylation [GO:0006486] GO:0000139; GO:0005789; GO:0006486; GO:0008417; GO:0036065; GO:0036071; GO:0046920 41421 XM_044316665.1 203 14 68 28 86 NA NA NA NA NA NA 41422 XM_029335418.2 0 14 15 23 0 F4NUJ6 3.16e-125 tRNA (guanine(37)-N1)-methyltransferase (EC 2.1.1.228) (M1G-methyltransferase) (tRNA [GM37] methyltransferase) (tRNA methyltransferase 5) Batrachochytrium dendrobatidis (strain JAM81 / FGSC 10211) (Frog chytrid fungus) mitochondrial tRNA methylation [GO:0070901]; tRNA methylation [GO:0030488]; tRNA N1-guanine methylation [GO:0002939] GO:0002939; GO:0005634; GO:0005737; GO:0005759; GO:0008175; GO:0009019; GO:0030488; GO:0052906; GO:0070901 41423 XM_029342032.2 0 0 0 0 50 Q28772 2.76e-31 Transcription factor 12 (TCF-12) (DNA-binding protein HTF4) (E-box-binding protein) (Transcription factor HTF-4) Papio hamadryas (Hamadryas baboon) cell differentiation [GO:0030154]; nervous system development [GO:0007399]; positive regulation of neuron differentiation [GO:0045666]; response to gonadotropin-releasing hormone [GO:0097210] GO:0005634; GO:0007399; GO:0030154; GO:0045666; GO:0046982; GO:0070888; GO:0097210 41424 XR_006394820.1 276 359 181 300 971 NA NA NA NA NA NA 41425 XR_006394105.1 97 224 115 18 89 NA NA NA NA NA NA 41426 XM_029351583.2 2998 2252 1089 1612 1084 P62489 7.55e-103 DNA-directed RNA polymerase II subunit RPB7 (RNA polymerase II subunit B7) (DNA-directed RNA polymerase II subunit G) Rattus norvegicus (Rat) apoptotic process [GO:0006915]; nuclear-transcribed mRNA catabolic process, exonucleolytic [GO:0000291]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of translational initiation [GO:0045948]; transcription by RNA polymerase II [GO:0006366]; transcription initiation at RNA polymerase II promoter [GO:0006367] GO:0000291; GO:0000932; GO:0003697; GO:0003727; GO:0005634; GO:0005665; GO:0006366; GO:0006367; GO:0006915; GO:0031369; GO:0045948; GO:0060213 41427 XM_044312022.1 596 483 365 445 522 P08510 7.17e-128 Potassium voltage-gated channel protein Shaker (Protein minisleep) Drosophila melanogaster (Fruit fly) action potential [GO:0001508]; axon extension [GO:0048675]; behavioral response to ether [GO:0048150]; cellular response to dopamine [GO:1903351]; courtship behavior [GO:0007619]; detection of visible light [GO:0009584]; larval locomotory behavior [GO:0008345]; learning or memory [GO:0007611]; mating behavior, sex discrimination [GO:0048047]; positive regulation of circadian sleep/wake cycle, sleep [GO:0045938]; positive regulation of membrane potential [GO:0045838]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; proboscis extension reflex [GO:0007637]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; regulation of ion transmembrane transport [GO:0034765]; regulation of synaptic activity [GO:0060025]; sensory perception of taste [GO:0050909]; sleep [GO:0030431] GO:0001508; GO:0005249; GO:0005251; GO:0006813; GO:0007611; GO:0007619; GO:0007637; GO:0008076; GO:0008345; GO:0009584; GO:0016020; GO:0022843; GO:0030431; GO:0034765; GO:0045187; GO:0045838; GO:0045938; GO:0048047; GO:0048150; GO:0048675; GO:0050909; GO:0051260; GO:0060025; GO:0071805; GO:1903351 41428 XR_006396142.1 5 4 11 4 5 NA NA NA NA NA NA 41429 XM_029345924.2 46 3 42 51 197 O75346 1.07e-65 Zinc finger protein 253 (Bone marrow zinc finger 1) (BMZF-1) (Zinc finger protein 411) Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; regulation of DNA-templated transcription [GO:0006355] GO:0000978; GO:0000981; GO:0005634; GO:0006355; GO:0045892; GO:0046872 41430 XM_029345924.2 46 3 42 51 197 O75346 2.82e-61 Zinc finger protein 253 (Bone marrow zinc finger 1) (BMZF-1) (Zinc finger protein 411) Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; regulation of DNA-templated transcription [GO:0006355] GO:0000978; GO:0000981; GO:0005634; GO:0006355; GO:0045892; GO:0046872 41431 XM_029345924.2 46 3 42 51 197 O75346 2.13e-60 Zinc finger protein 253 (Bone marrow zinc finger 1) (BMZF-1) (Zinc finger protein 411) Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; regulation of DNA-templated transcription [GO:0006355] GO:0000978; GO:0000981; GO:0005634; GO:0006355; GO:0045892; GO:0046872 41432 XM_029345924.2 46 3 42 51 197 O75346 3.18e-50 Zinc finger protein 253 (Bone marrow zinc finger 1) (BMZF-1) (Zinc finger protein 411) Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; regulation of DNA-templated transcription [GO:0006355] GO:0000978; GO:0000981; GO:0005634; GO:0006355; GO:0045892; GO:0046872 41433 XM_029345924.2 46 3 42 51 197 O75346 4.61e-33 Zinc finger protein 253 (Bone marrow zinc finger 1) (BMZF-1) (Zinc finger protein 411) Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; regulation of DNA-templated transcription [GO:0006355] GO:0000978; GO:0000981; GO:0005634; GO:0006355; GO:0045892; GO:0046872 41434 XM_044325591.1 97 53 89 89 99 NA NA NA NA NA NA 41435 XM_029339862.2 905 496 320 673 688 Q6DFF6 4.07e-130 Kelch-like protein 20 Xenopus laevis (African clawed frog) Golgi to endosome transport [GO:0006895]; negative regulation of apoptotic process [GO:0043066]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K33-linked ubiquitination [GO:1990390]; protein transport [GO:0015031]; protein ubiquitination [GO:0016567] GO:0004842; GO:0005737; GO:0005802; GO:0005829; GO:0006895; GO:0015031; GO:0016567; GO:0016605; GO:0019964; GO:0031463; GO:0043066; GO:0043161; GO:0048471; GO:1990390 41436 XM_044328210.1 548 272 318 501 306 NA NA NA NA NA NA 41437 XM_044325139.1 40 61 0 5 2 NA NA NA NA NA NA 41438 XR_006394626.1 31 5 0 10 5 NA NA NA NA NA NA 41439 XM_044319245.1 6 0 0 0 0 Q3T052 4e-106 Inter-alpha-trypsin inhibitor heavy chain H4 (ITI heavy chain H4) (ITI-HC4) (Inter-alpha-inhibitor heavy chain 4) Bos taurus (Bovine) acute-phase response [GO:0006953]; hyaluronan metabolic process [GO:0030212]; negative regulation of peptidase activity [GO:0010466] GO:0004867; GO:0005576; GO:0006953; GO:0010466; GO:0030212 41440 XM_044326231.1 39 33 31 24 58 NA NA NA NA NA NA 41441 XM_044317153.1 1 4 9 37 12 NA NA NA NA NA NA 41442 XM_044320967.1 101 22 22 0 0 NA NA NA NA NA NA 41443 XM_029338530.2 442 364 238 287 248 O14735 5.43e-83 CDP-diacylglycerol--inositol 3-phosphatidyltransferase (EC 2.7.8.11) (Phosphatidylinositol synthase) (PI synthase) (PtdIns synthase) Homo sapiens (Human) CDP-diacylglycerol metabolic process [GO:0046341]; phosphatidylinositol biosynthetic process [GO:0006661] GO:0003881; GO:0005789; GO:0005794; GO:0005886; GO:0006661; GO:0016020; GO:0019992; GO:0030145; GO:0030246; GO:0043178; GO:0046341 41444 XM_029353924.2 909 404 429 666 591 Q9ZNT0 1.14e-74 Protein SUPPRESSOR OF K(+) TRANSPORT GROWTH DEFECT 1 (AtSKD1) (EC 3.6.4.6) (Protein VACUOLAR PROTEIN SORTING 4) Arabidopsis thaliana (Mouse-ear cress) cell cycle [GO:0007049]; endosomal transport [GO:0016197]; endosome organization [GO:0007032]; potassium ion homeostasis [GO:0055075]; protein transport [GO:0015031]; sodium ion homeostasis [GO:0055078]; trichome branching [GO:0010091]; vacuole organization [GO:0007033]; vesicle-mediated transport [GO:0016192] GO:0005524; GO:0005634; GO:0005737; GO:0005771; GO:0005777; GO:0007032; GO:0007033; GO:0007049; GO:0009506; GO:0010091; GO:0015031; GO:0016192; GO:0016197; GO:0016887; GO:0032585; GO:0055075; GO:0055078 41445 XM_029353482.2 1337 1058 825 1786 2997 Q5RBA4 4.86e-64 Myosin regulatory light polypeptide 9 (Myosin regulatory light chain 2, smooth muscle isoform) (Myosin regulatory light chain 9) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0005509; GO:0005938; GO:0016459 41446 XR_003827585.2 21 10 42 9 133 NA NA NA NA NA NA 41447 XM_029334819.2 352 95 290 532 203 Q5ZJH6 1.23e-30 Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3) Gallus gallus (Chicken) autophagosome organization [GO:1905037]; negative regulation of smoothened signaling pathway [GO:0045879]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of smoothened signaling pathway [GO:0045880]; protein autophosphorylation [GO:0046777] GO:0000407; GO:0004674; GO:0005524; GO:0005737; GO:0005776; GO:0018105; GO:0045879; GO:0045880; GO:0046777; GO:0106310; GO:1905037 41448 XM_029327069.2 29 13 32 0 9 A0JPI9 6.55e-75 Leucine-rich repeat-containing protein 74A (Leucine-rich repeat-containing protein 74) Rattus norvegicus (Rat) NA NA 41449 XM_029347003.2 908 1258 546 1169 774 NA NA NA NA NA NA 41450 XM_029335384.2 64 38 17 72 5 NA NA NA NA NA NA 41451 XM_029351952.2 136 0 0 275 53 NA NA NA NA NA NA 41452 XM_044316797.1 0 3 3 1 8 NA NA NA NA NA NA 41453 XM_029345561.2 57 129 111 250 147 Q6GQX6 1.57e-87 Ankyrin repeat and SAM domain-containing protein 6 (SamCystin) (Sterile alpha motif domain-containing protein 6) (SAM domain-containing protein 6) Mus musculus (Mouse) determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822] GO:0001701; GO:0001822; GO:0005737; GO:0007368; GO:0007507; GO:0042802; GO:0097543 41454 XM_029345561.2 57 129 111 250 147 Q6GQX6 6.99e-22 Ankyrin repeat and SAM domain-containing protein 6 (SamCystin) (Sterile alpha motif domain-containing protein 6) (SAM domain-containing protein 6) Mus musculus (Mouse) determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822] GO:0001701; GO:0001822; GO:0005737; GO:0007368; GO:0007507; GO:0042802; GO:0097543 41455 XM_029353270.2 7 58 6 7 21 NA NA NA NA NA NA 41456 XM_044325035.1 24 65 26 56 60 NA NA NA NA NA NA 41457 XM_044320170.1 533 0 58 777 337 Q5DTN8 9.24e-50 Janus kinase and microtubule-interacting protein 3 (Neuroendocrine long coiled-coil protein 2) Mus musculus (Mouse) NA GO:0005794; GO:0008017; GO:0019900 41458 XM_029330650.2 2713 1103 864 2647 2717 Q5U4Y8 8.4e-171 Nucleoporin SEH1 (GATOR complex protein SEH1) (Nup107-160 subcomplex subunit seh1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) attachment of mitotic spindle microtubules to kinetochore [GO:0051315]; cell division [GO:0051301]; mitotic metaphase plate congression [GO:0007080]; mRNA transport [GO:0051028]; nuclear pore organization [GO:0006999]; protein transport [GO:0015031] GO:0000776; GO:0005198; GO:0005765; GO:0006999; GO:0007080; GO:0015031; GO:0031080; GO:0051028; GO:0051301; GO:0051315 41459 XM_029339158.2 633 460 236 504 258 A4QNE6 0 Dynein axonemal assembly factor 10 (WD repeat-containing protein 92) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) apoptotic process [GO:0006915]; axonemal dynein complex assembly [GO:0070286] GO:0006915; GO:0070286; GO:0120293 41460 XM_029336852.2 0 1 10 4 6 NA NA NA NA NA NA 41461 XM_044328297.1 5 0 5 0 13 NA NA NA NA NA NA 41462 XM_044310704.1 65 3 107 1 217 NA NA NA NA NA NA 41463 XR_003828011.2 29 50 13 79 51 NA NA NA NA NA NA 41464 XM_044318288.1 2 0 20 6 41 NA NA NA NA NA NA 41465 XR_006396546.1 9 5 0 21 3 Q3U9N9 5.68e-41 Monocarboxylate transporter 10 (MCT 10) (Aromatic amino acid transporter 1) (Solute carrier family 16 member 10) (T-type amino acid transporter 1) Mus musculus (Mouse) aromatic amino acid transport [GO:0015801]; thyroid hormone generation [GO:0006590]; thyroid hormone transport [GO:0070327]; thyroid-stimulating hormone secretion [GO:0070460] GO:0005302; GO:0005886; GO:0006590; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0030054; GO:0043231; GO:0070327; GO:0070460 41466 XR_006396546.1 9 5 0 21 3 Q3U9N9 5.68e-41 Monocarboxylate transporter 10 (MCT 10) (Aromatic amino acid transporter 1) (Solute carrier family 16 member 10) (T-type amino acid transporter 1) Mus musculus (Mouse) aromatic amino acid transport [GO:0015801]; thyroid hormone generation [GO:0006590]; thyroid hormone transport [GO:0070327]; thyroid-stimulating hormone secretion [GO:0070460] GO:0005302; GO:0005886; GO:0006590; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0030054; GO:0043231; GO:0070327; GO:0070460 41467 XM_029323850.2 0 0 0 18 18 NA NA NA NA NA NA 41468 XM_044322218.1 961 1355 1044 2405 1328 NA NA NA NA NA NA 41469 XM_029332150.2 258 150 58 283 228 NA NA NA NA NA NA 41470 XM_029332857.2 189 1 41 110 157 NA NA NA NA NA NA 41471 XM_044316133.1 2245 1776 734 1379 1409 Q5RFJ1 1.6e-114 Interleukin enhancer-binding factor 2 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) positive regulation of DNA-templated transcription [GO:0045893] GO:0003677; GO:0003725; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0045893; GO:1990904 41472 XM_029343969.2 334 347 311 253 607 P58044 1.21e-88 Isopentenyl-diphosphate Delta-isomerase 1 (EC 5.3.3.2) (Isopentenyl pyrophosphate isomerase 1) (IPP isomerase 1) (IPPI1) Mus musculus (Mouse) cholesterol biosynthetic process [GO:0006695]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process [GO:0009240]; isoprenoid biosynthetic process [GO:0008299]; response to stilbenoid [GO:0035634] GO:0000287; GO:0004452; GO:0005737; GO:0005739; GO:0005777; GO:0006695; GO:0008299; GO:0009240; GO:0030145; GO:0035634; GO:0050992 41473 XM_029331430.2 0 82 0 179 427 Q91V01 3.07e-87 Lysophospholipid acyltransferase 5 (LPLAT 5) (EC 2.3.1.-) (1-acylglycerophosphocholine O-acyltransferase) (EC 2.3.1.23) (1-acylglycerophosphoethanolamine O-acyltransferase) (EC 2.3.1.n7) (1-acylglycerophosphoserine O-acyltransferase) (EC 2.3.1.n6) (Lysophosphatidylcholine acyltransferase) (LPCAT) (Lyso-PC acyltransferase) (Lysophosphatidylcholine acyltransferase 3) (Lyso-PC acyltransferase 3) (mLPCAT3) (Lysophosphatidylethanolamine acyltransferase) (LPEAT) (Lyso-PE acyltransferase) (Lysophosphatidylserine acyltransferase) (LPSAT) (Lyso-PS acyltransferase) (Membrane-bound O-acyltransferase domain-containing protein 5) (O-acyltransferase domain-containing protein 5) Mus musculus (Mouse) chylomicron assembly [GO:0034378]; endoplasmic reticulum membrane organization [GO:0090158]; intestinal stem cell homeostasis [GO:0036335]; lipid modification [GO:0030258]; negative regulation of inflammatory response [GO:0050728]; negative regulation of response to endoplasmic reticulum stress [GO:1903573]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylcholine biosynthetic process [GO:0006656]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; phosphatidylserine acyl-chain remodeling [GO:0036150]; positive regulation of intestinal cholesterol absorption [GO:0045797]; positive regulation of sterol regulatory element binding protein cleavage [GO:1901310]; positive regulation of triglyceride transport [GO:1905885]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of plasma lipoprotein particle levels [GO:0097006]; very-low-density lipoprotein particle assembly [GO:0034379] GO:0005789; GO:0006656; GO:0016020; GO:0016746; GO:0030258; GO:0034378; GO:0034379; GO:0036150; GO:0036151; GO:0036152; GO:0036335; GO:0045540; GO:0045797; GO:0047184; GO:0050728; GO:0071617; GO:0090158; GO:0097006; GO:0106262; GO:0106263; GO:1901310; GO:1903573; GO:1905885 41474 XR_006395793.1 136 776 234 1142 666 NA NA NA NA NA NA 41475 XM_029330118.2 65 132 51 109 100 P23359 6.88e-23 Bone morphogenetic protein 7 (BMP-7) (Osteogenic protein 1) (OP-1) Mus musculus (Mouse) allantois development [GO:1905069]; ameloblast differentiation [GO:0036305]; anatomical structure formation involved in morphogenesis [GO:0048646]; animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; BMP signaling pathway [GO:0030509]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle tissue development [GO:0048738]; cardiac septum morphogenesis [GO:0060411]; cartilage development [GO:0051216]; cell development [GO:0048468]; cell population proliferation [GO:0008283]; cellular response to BMP stimulus [GO:0071773]; chorio-allantoic fusion [GO:0060710]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic skeletal joint morphogenesis [GO:0060272]; endocardial cushion formation [GO:0003272]; epithelial cell differentiation [GO:0030855]; eye development [GO:0001654]; heart trabecula morphogenesis [GO:0061384]; hindbrain development [GO:0030902]; kidney development [GO:0001822]; mesenchymal cell apoptotic process involved in nephron morphogenesis [GO:1901145]; mesenchymal cell differentiation [GO:0048762]; mesenchyme development [GO:0060485]; mesoderm formation [GO:0001707]; metanephric mesenchymal cell proliferation involved in metanephros development [GO:0072136]; metanephric mesenchyme morphogenesis [GO:0072133]; monocyte aggregation [GO:0070487]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell death [GO:0060548]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of glomerular mesangial cell proliferation [GO:0072125]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis [GO:0072040]; negative regulation of mitotic nuclear division [GO:0045839]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of phosphorylation [GO:0042326]; negative regulation of prostatic bud formation [GO:0060686]; nephrogenic mesenchyme morphogenesis [GO:0072134]; neural fold elevation formation [GO:0021502]; neuron projection morphogenesis [GO:0048812]; odontogenesis of dentin-containing tooth [GO:0042475]; ossification [GO:0001503]; pattern specification process [GO:0007389]; pericardium morphogenesis [GO:0003344]; pharyngeal system development [GO:0060037]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone mineralization [GO:0030501]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis [GO:1905312]; positive regulation of cell death [GO:0010942]; positive regulation of dendrite development [GO:1900006]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial cell differentiation [GO:0030858]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of gene expression [GO:0010628]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of hyaluranon cable assembly [GO:1900106]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to nucleus [GO:0034504]; regulation of branching involved in prostate gland morphogenesis [GO:0060687]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of phosphorylation [GO:0042325]; response to estradiol [GO:0032355]; response to peptide hormone [GO:0043434]; response to vitamin D [GO:0033280]; salivary gland morphogenesis [GO:0007435]; SMAD protein signal transduction [GO:0060395]; steroid hormone mediated signaling pathway [GO:0043401]; tube morphogenesis [GO:0035239]; ureteric bud development [GO:0001657] GO:0001503; GO:0001654; GO:0001657; GO:0001707; GO:0001822; GO:0003272; GO:0003344; GO:0005125; GO:0005615; GO:0007389; GO:0007411; GO:0007435; GO:0008083; GO:0008201; GO:0008283; GO:0008285; GO:0009880; GO:0009887; GO:0010628; GO:0010718; GO:0010800; GO:0010862; GO:0010942; GO:0021502; GO:0030326; GO:0030501; GO:0030509; GO:0030855; GO:0030858; GO:0030902; GO:0031982; GO:0032355; GO:0033280; GO:0034116; GO:0034504; GO:0035239; GO:0036305; GO:0042325; GO:0042326; GO:0042475; GO:0043065; GO:0043401; GO:0043407; GO:0043434; GO:0045665; GO:0045666; GO:0045669; GO:0045746; GO:0045786; GO:0045839; GO:0045892; GO:0045893; GO:0045944; GO:0048468; GO:0048593; GO:0048596; GO:0048646; GO:0048738; GO:0048754; GO:0048762; GO:0048812; GO:0050768; GO:0051216; GO:0060037; GO:0060272; GO:0060391; GO:0060393; GO:0060395; GO:0060411; GO:0060445; GO:0060485; GO:0060548; GO:0060686; GO:0060687; GO:0060710; GO:0061384; GO:0062023; GO:0070487; GO:0070700; GO:0071773; GO:0072040; GO:0072125; GO:0072133; GO:0072134; GO:0072136; GO:0090336; GO:1900006; GO:1900106; GO:1901145; GO:1905069; GO:1905312 41476 XM_029333078.2 44 0 0 69 66 Q0V8E4 1.22e-114 Asparagine synthetase domain-containing protein 1 Bos taurus (Bovine) asparagine biosynthetic process [GO:0006529]; glutamine metabolic process [GO:0006541] GO:0004066; GO:0006529; GO:0006541 41477 XM_029333078.2 44 0 0 69 66 Q0V8E4 5.85e-43 Asparagine synthetase domain-containing protein 1 Bos taurus (Bovine) asparagine biosynthetic process [GO:0006529]; glutamine metabolic process [GO:0006541] GO:0004066; GO:0006529; GO:0006541 41478 XM_029348354.2 311 136 214 393 299 P08873 1.76e-21 Basic phospholipase A2 notechis 11'2 (svPLA2) (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase) Notechis scutatus scutatus (Mainland tiger snake) (Common tiger snake) arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644] GO:0004623; GO:0005509; GO:0005576; GO:0006644; GO:0016042; GO:0050482 41479 XM_029340911.2 37 9 29 20 60 B2RPY5 6.3e-21 G-protein coupled receptor 161 Mus musculus (Mouse) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:1901621] GO:0004930; GO:0005929; GO:0007186; GO:0007189; GO:0043005; GO:0055037; GO:0060170; GO:0097386; GO:1901621 41480 XR_006398077.1 4 0 10 2 1 NA NA NA NA NA NA 41481 XM_029335173.2 97 84 84 21 64 E1BY51 2.44e-47 Transmembrane protein 17 Gallus gallus (Chicken) cilium assembly [GO:0060271]; non-motile cilium assembly [GO:1905515]; smoothened signaling pathway [GO:0007224] GO:0007224; GO:0035869; GO:0036038; GO:0060170; GO:0060271; GO:1905515 41482 XM_044326640.1 2 0 1 6 1 Q96AY4 9.15e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41483 XM_044326640.1 2 0 1 6 1 Q96AY4 8.91e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41484 XM_044326640.1 2 0 1 6 1 Q96AY4 4.25e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41485 XM_044326640.1 2 0 1 6 1 Q96AY4 8.76e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41486 XM_044326640.1 2 0 1 6 1 Q96AY4 1.13e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41487 XM_044326640.1 2 0 1 6 1 Q96AY4 9.96e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41488 XM_044326640.1 2 0 1 6 1 Q96AY4 1.18e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41489 XM_044326640.1 2 0 1 6 1 Q96AY4 5.43e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41490 XM_044326640.1 2 0 1 6 1 Q96AY4 7.23e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 41491 XM_044318398.1 0 0 5 0 10 P0CT40 4e-76 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 41492 XM_044319288.1 455 130 122 332 289 NA NA NA NA NA NA 41493 XM_029348766.2 299 444 164 266 515 Q570Y9 1.02e-36 DEP domain-containing mTOR-interacting protein (DEP domain-containing protein 6) Mus musculus (Mouse) intracellular signal transduction [GO:0035556]; negative regulation of cell size [GO:0045792]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of TOR signaling [GO:0032007]; negative regulation of TORC1 signaling [GO:1904262]; negative regulation of TORC2 signaling [GO:1903940]; regulation of extrinsic apoptotic signaling pathway [GO:2001236] GO:0006469; GO:0032007; GO:0035556; GO:0045792; GO:1903940; GO:1904262; GO:2001236 41494 XM_044325696.1 0 0 5 13 1 NA NA NA NA NA NA 41495 XM_044321242.1 7 0 0 5 7 NA NA NA NA NA NA 41496 XR_003828165.2 13 49 15 0 0 NA NA NA NA NA NA 41497 XR_006394975.1 56 8 42 13 61 NA NA NA NA NA NA 41498 XM_044329261.1 19 0 10 0 142 NA NA NA NA NA NA 41499 XR_006395425.1 0 13 0 1 15 NA NA NA NA NA NA 41500 XM_029331098.2 2939 2121 1742 4270 3461 F1M386 0 Rap guanine nucleotide exchange factor 2 (Cyclic nucleotide ras GEF) (CNrasGEF) (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF-1) (Ras/Rap1-associating GEF-1) Rattus norvegicus (Rat) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; blood vessel development [GO:0001568]; brain-derived neurotrophic factor receptor signaling pathway [GO:0031547]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to nerve growth factor stimulus [GO:1990090]; establishment of endothelial barrier [GO:0061028]; establishment of endothelial intestinal barrier [GO:0090557]; forebrain neuron development [GO:0021884]; G protein-coupled receptor signaling pathway [GO:0007186]; microvillus assembly [GO:0030033]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of dendrite morphogenesis [GO:0050774]; negative regulation of melanin biosynthetic process [GO:0048022]; nerve growth factor signaling pathway [GO:0038180]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; neuropeptide signaling pathway [GO:0007218]; positive regulation of cAMP-dependent protein kinase activity [GO:2000481]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron migration [GO:2001224]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein binding [GO:0032092]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of vasculogenesis [GO:2001214]; protein localization to plasma membrane [GO:0072659]; proteolysis [GO:0006508]; Rap protein signal transduction [GO:0032486]; Ras protein signal transduction [GO:0007265]; regulation of cell junction assembly [GO:1901888]; regulation of synaptic plasticity [GO:0048167]; ventricular system development [GO:0021591] GO:0001568; GO:0001764; GO:0004222; GO:0005085; GO:0005096; GO:0005737; GO:0005770; GO:0005886; GO:0005911; GO:0005923; GO:0006508; GO:0007186; GO:0007218; GO:0007265; GO:0008285; GO:0010976; GO:0016020; GO:0016324; GO:0019901; GO:0019933; GO:0021591; GO:0021884; GO:0030033; GO:0030139; GO:0030165; GO:0030552; GO:0031175; GO:0031547; GO:0031697; GO:0032092; GO:0032486; GO:0032991; GO:0038180; GO:0043005; GO:0043025; GO:0043547; GO:0043950; GO:0045202; GO:0045860; GO:0048022; GO:0048167; GO:0048471; GO:0050699; GO:0050774; GO:0061028; GO:0070300; GO:0070374; GO:0071320; GO:0071321; GO:0071880; GO:0072659; GO:0090557; GO:1901888; GO:1990090; GO:2000481; GO:2000670; GO:2001214; GO:2001224 41501 XR_003823603.2 26 5 0 2 23 NA NA NA NA NA NA 41502 XM_044313763.1 22 0 25 2 22 NA NA NA NA NA NA 41503 XM_044326893.1 9 2 5 0 76 D3YXG0 2.49e-47 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 41504 XM_044326893.1 9 2 5 0 76 D3YXG0 7.32e-46 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 41505 XM_044326893.1 9 2 5 0 76 D3YXG0 1.03e-40 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 41506 XM_044326893.1 9 2 5 0 76 D3YXG0 2.1e-39 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 41507 XM_044326893.1 9 2 5 0 76 D3YXG0 1.06e-38 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 41508 XM_044326893.1 9 2 5 0 76 D3YXG0 1.06e-38 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 41509 XM_044326893.1 9 2 5 0 76 D3YXG0 1.91e-38 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 41510 XM_044326893.1 9 2 5 0 76 D3YXG0 2.19e-38 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 41511 XM_044326893.1 9 2 5 0 76 D3YXG0 1.04e-37 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 41512 XM_044326893.1 9 2 5 0 76 D3YXG0 2.2e-36 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 41513 XM_044326893.1 9 2 5 0 76 D3YXG0 2.24e-36 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 41514 XM_044326893.1 9 2 5 0 76 D3YXG0 8.61e-36 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 41515 XM_044326893.1 9 2 5 0 76 D3YXG0 1.05e-34 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 41516 XM_044326893.1 9 2 5 0 76 D3YXG0 2.83e-33 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 41517 XM_044326893.1 9 2 5 0 76 D3YXG0 3.37e-33 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 41518 XM_044326893.1 9 2 5 0 76 D3YXG0 1.53e-30 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 41519 XM_044326893.1 9 2 5 0 76 D3YXG0 1.67e-30 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 41520 XM_044326893.1 9 2 5 0 76 D3YXG0 2.57e-29 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 41521 XM_044326893.1 9 2 5 0 76 D3YXG0 3.16e-28 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 41522 XM_029350449.2 788 669 589 1063 1051 O77649 4.04e-65 UDP-glucuronosyltransferase 2B20 (UDPGT 2B20) (EC 2.4.1.17) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0005789; GO:0015020 41523 XM_044328662.1 44 0 77 0 0 P28606 3.01e-88 Uncharacterized protein SYNPCC7002_A1628 Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (Agmenellum quadruplicatum) histone deacetylation [GO:0016575] GO:0004407; GO:0016575 41524 XM_029358437.2 980 820 451 496 507 Q5XGI5 1e-129 WD repeat domain-containing protein 83 (Mitogen-activated protein kinase organizer 1) (MAPK organizer 1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737 41525 XM_029343114.2 1683 1419 1121 1262 1450 Q6NU04 1.24e-28 Tudor domain-containing protein 7 Xenopus laevis (African clawed frog) lens fiber cell differentiation [GO:0070306]; lens morphogenesis in camera-type eye [GO:0002089]; post-transcriptional regulation of gene expression [GO:0010608]; spermatogenesis [GO:0007283] GO:0002089; GO:0003729; GO:0005737; GO:0007283; GO:0010608; GO:0035770; GO:0070306 41526 XM_029338576.2 285 120 83 299 223 NA NA NA NA NA NA 41527 XM_029351647.2 297 43 104 110 79 Q13615 0 Myotubularin-related protein 3 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 1) (FYVE-DSP1) (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64) (Zinc finger FYVE domain-containing protein 10) Homo sapiens (Human) cellular response to glucose starvation [GO:0042149]; macroautophagy [GO:0016236]; phosphatidylinositol 5-phosphate metabolic process [GO:1904562]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; protein dephosphorylation [GO:0006470]; regulation of autophagosome assembly [GO:2000785]; regulation of autophagy [GO:0010506]; regulation of phosphatidylinositol dephosphorylation [GO:0060304] GO:0004438; GO:0004722; GO:0004725; GO:0005737; GO:0005829; GO:0006470; GO:0006661; GO:0008138; GO:0010506; GO:0016020; GO:0016236; GO:0019898; GO:0019903; GO:0042149; GO:0046856; GO:0046872; GO:0052629; GO:0060304; GO:1904562; GO:2000785 41528 XM_029351647.2 297 43 104 110 79 Q13615 4.28e-35 Myotubularin-related protein 3 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 1) (FYVE-DSP1) (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64) (Zinc finger FYVE domain-containing protein 10) Homo sapiens (Human) cellular response to glucose starvation [GO:0042149]; macroautophagy [GO:0016236]; phosphatidylinositol 5-phosphate metabolic process [GO:1904562]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; protein dephosphorylation [GO:0006470]; regulation of autophagosome assembly [GO:2000785]; regulation of autophagy [GO:0010506]; regulation of phosphatidylinositol dephosphorylation [GO:0060304] GO:0004438; GO:0004722; GO:0004725; GO:0005737; GO:0005829; GO:0006470; GO:0006661; GO:0008138; GO:0010506; GO:0016020; GO:0016236; GO:0019898; GO:0019903; GO:0042149; GO:0046856; GO:0046872; GO:0052629; GO:0060304; GO:1904562; GO:2000785 41529 XM_044320942.1 703 363 436 743 1176 Q8NB14 9.1e-116 Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.4.19.12) (Deubiquitinating enzyme 38) (HP43.8KD) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) Homo sapiens (Human) protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004197; GO:0004843; GO:0005634; GO:0005829; GO:0006511; GO:0016579 41530 XM_044320942.1 703 363 436 743 1176 Q8NB14 3.38e-39 Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.4.19.12) (Deubiquitinating enzyme 38) (HP43.8KD) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) Homo sapiens (Human) protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004197; GO:0004843; GO:0005634; GO:0005829; GO:0006511; GO:0016579 41531 XM_044320942.1 703 363 436 743 1176 Q8NB14 3.38e-39 Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.4.19.12) (Deubiquitinating enzyme 38) (HP43.8KD) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) Homo sapiens (Human) protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004197; GO:0004843; GO:0005634; GO:0005829; GO:0006511; GO:0016579 41532 XM_044328973.1 8 3 11 18 13 NA NA NA NA NA NA 41533 XM_029330816.2 1236 231 158 380 309 A5D6U8 4.69e-98 Acid phosphatase type 7 (EC 3.1.3.2) (Purple acid phosphatase long form) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0003993; GO:0005576; GO:0046872 41534 XR_003823034.2 926 60 458 32 68 NA NA NA NA NA NA 41535 XM_044307098.1 1113 1011 387 434 423 Q05B60 4.24e-51 Uridine diphosphate glucose pyrophosphatase NUDT14 (UDPG pyrophosphatase) (UGPPase) (EC 3.6.1.45) (Nucleoside diphosphate-linked moiety X motif 14) (Nudix motif 14) Bos taurus (Bovine) nucleoside phosphate metabolic process [GO:0006753]; ribose phosphate metabolic process [GO:0019693] GO:0005737; GO:0006753; GO:0008768; GO:0019693; GO:0042802; GO:0046872; GO:0047631 41536 XM_044312517.1 44 0 9 2 18 NA NA NA NA NA NA 41537 XM_044315908.1 8 0 0 0 0 NA NA NA NA NA NA 41538 XM_029346785.2 22 13 6 17 6 NA NA NA NA NA NA 41539 XM_029343018.2 80 36 28 43 39 P58283 3.36e-92 E3 ubiquitin-protein ligase RNF216 (EC 2.3.2.27) (RING finger protein 216) (RING-type E3 ubiquitin transferase RNF216) (Triad domain-containing protein 3) (UbcM4-interacting protein 83) (Ubiquitin-conjugating enzyme 7-interacting protein 1) Mus musculus (Mouse) apoptotic process [GO:0006915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein catabolic process, modulating synaptic transmission [GO:0099546]; protein K48-linked ubiquitination [GO:0070936]; regulation of defense response to virus by host [GO:0050691]; regulation of interferon-beta production [GO:0032648]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149] GO:0005634; GO:0005654; GO:0005829; GO:0006915; GO:0032648; GO:0043161; GO:0046872; GO:0050691; GO:0061630; GO:0070936; GO:0098685; GO:0098793; GO:0098843; GO:0098978; GO:0099149; GO:0099546 41540 XR_006397997.1 205 107 202 560 88 NA NA NA NA NA NA 41541 XR_006395168.1 124 697 550 157 246 Q95117 8.02e-23 Secreted frizzled-related protein 3 (sFRP-3) (Frizzled-related protein 1) (FrzB-1) Bos taurus (Bovine) canonical Wnt signaling pathway [GO:0060070]; cochlea morphogenesis [GO:0090103]; convergent extension involved in organogenesis [GO:0060029]; epithelial cell development [GO:0002064]; hepatocyte differentiation [GO:0070365]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cartilage development [GO:0061037]; negative regulation of cell development [GO:0010721]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of hepatocyte differentiation [GO:0070367]; negative regulation of Wnt signaling pathway [GO:0030178]; neural crest cell differentiation [GO:0014033]; positive regulation of apoptotic process [GO:0043065]; positive regulation of fat cell differentiation [GO:0045600]; somite development [GO:0061053] GO:0002064; GO:0005615; GO:0005737; GO:0008285; GO:0010721; GO:0014033; GO:0017147; GO:0030178; GO:0030308; GO:0043065; GO:0045600; GO:0060029; GO:0060070; GO:0061037; GO:0061053; GO:0070365; GO:0070367; GO:0090090; GO:0090103 41542 XM_029327093.2 96 36 63 15 107 Q9J569 1.05e-22 Putative ankyrin repeat protein FPV162 Fowlpox virus (strain NVSL) (FPV) NA NA 41543 XM_029339610.2 781 271 365 424 385 Q96N46 6.09e-61 Tetratricopeptide repeat protein 14 (TPR repeat protein 14) Homo sapiens (Human) NA GO:0003676 41544 XM_029344677.2 113 78 67 141 275 NA NA NA NA NA NA 41545 XM_029336905.2 254 48 97 196 53 NA NA NA NA NA NA 41546 XM_029334667.2 0 7 7 42 0 Q9SSA4 1.53e-31 NA NA NA NA 41547 XM_044321136.1 43 35 52 8 33 NA NA NA NA NA NA 41548 XM_044320337.1 44 0 0 0 40 Q804R0 8.94e-33 Transcription factor LBX2 (Ladybird homeobox 2) (Ladybird homeobox protein homolog 2) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic axis specification [GO:0000578]; muscle cell development [GO:0055001]; muscle cell differentiation [GO:0042692]; positive regulation of convergent extension involved in gastrulation [GO:1904105]; positive regulation of non-canonical Wnt signaling pathway [GO:2000052]; posterior lateral line neuromast deposition [GO:0048922]; posterior lateral line neuromast primordium migration [GO:0048920]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000578; GO:0000981; GO:0005634; GO:0006357; GO:0042692; GO:0048920; GO:0048922; GO:0055001; GO:0060828; GO:1904105; GO:1990837; GO:2000052 41549 XM_029333069.2 0 0 70 12 356 Q6P8Y1 5.38e-73 Calcyphosin-like protein Mus musculus (Mouse) NA GO:0005509; GO:0005737 41550 XR_006393882.1 2 0 0 10 8 NA NA NA NA NA NA 41551 XM_029349303.2 128 0 108 0 284 P04274 4.33e-24 Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor) Mesocricetus auratus (Golden hamster) activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; bone resorption [GO:0045453]; brown fat cell differentiation [GO:0050873]; cellular response to amyloid-beta [GO:1904646]; desensitization of G protein-coupled receptor signaling pathway by arrestin [GO:0002032]; diet induced thermogenesis [GO:0002024]; heat generation [GO:0031649]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of smooth muscle contraction [GO:0045986]; norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0002025]; positive regulation of AMPA receptor activity [GO:2000969]; positive regulation of autophagosome maturation [GO:1901098]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of lipophagy [GO:1904504]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mini excitatory postsynaptic potential [GO:0061885]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor-mediated endocytosis [GO:0006898]; regulation of sodium ion transport [GO:0002028]; response to cold [GO:0009409]; smooth muscle contraction [GO:0006939]; transcription by RNA polymerase II [GO:0006366] GO:0001540; GO:0002024; GO:0002025; GO:0002028; GO:0002032; GO:0004941; GO:0005634; GO:0005769; GO:0005794; GO:0006366; GO:0006898; GO:0006939; GO:0007189; GO:0007190; GO:0008179; GO:0009409; GO:0010739; GO:0015459; GO:0016324; GO:0030501; GO:0031649; GO:0040015; GO:0042803; GO:0043235; GO:0043410; GO:0044877; GO:0045453; GO:0045944; GO:0045986; GO:0050873; GO:0051380; GO:0061885; GO:0071902; GO:0098992; GO:0120162; GO:1901098; GO:1904504; GO:1904646; GO:2000969 41552 XM_044321814.1 1 85 38 15 51 Q80XJ3 1.5e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 41553 XM_044320294.1 357 286 194 555 373 NA NA NA NA NA NA 41554 XM_044309015.1 312 541 127 401 826 NA NA NA NA NA NA 41555 XM_044317089.1 36 44 41 13 2 Q9N126 2.59e-64 Retinol dehydrogenase 8 (EC 1.1.1.300) (Photoreceptor outer segment all-trans retinol dehydrogenase) Bos taurus (Bovine) estrogen biosynthetic process [GO:0006703]; response to stimulus [GO:0050896]; retinol metabolic process [GO:0042572]; visual perception [GO:0007601] GO:0004303; GO:0004745; GO:0005829; GO:0006703; GO:0007601; GO:0016491; GO:0042572; GO:0042622; GO:0050896; GO:0052650 41556 XM_044323821.1 730 0 716 1275 353 Q15434 4.94e-77 RNA-binding motif, single-stranded-interacting protein 2 (Suppressor of CDC2 with RNA-binding motif 3) Homo sapiens (Human) RNA processing [GO:0006396] GO:0003723; GO:0003730; GO:0005634; GO:0005829; GO:0006396; GO:0008143; GO:0008266; GO:1990904 41557 XM_029339086.2 1455 1286 338 1201 1151 Q9CYL5 5.99e-39 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Mus musculus (Mouse) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070374 41558 XM_029339086.2 1455 1286 338 1201 1151 Q9CYL5 4.87e-35 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Mus musculus (Mouse) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070374 41559 XR_006395837.1 323 561 303 538 468 Q2KIP7 1.98e-64 Mitotic spindle assembly checkpoint protein MAD2B (Mitotic arrest deficient 2-like protein 2) (MAD2-like protein 2) Bos taurus (Bovine) cell cycle [GO:0007049]; cell division [GO:0051301]; DNA damage response, signal transduction resulting in transcription [GO:0042772]; double-strand break repair [GO:0006302]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of ubiquitin protein ligase activity [GO:1904667]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; regulation of cell growth [GO:0001558] GO:0001558; GO:0005634; GO:0005737; GO:0005819; GO:0006302; GO:0007049; GO:0008432; GO:0016035; GO:0033138; GO:0042177; GO:0042772; GO:0045893; GO:0051301; GO:1904667 41560 XM_044326186.1 22 27 19 1 26 NA NA NA NA NA NA 41561 XM_029347528.2 1250 1902 785 747 752 E0ZS45 5.06e-43 Urease accessory protein D (AtURED) Oryza sativa subsp. indica (Rice) nitrogen compound metabolic process [GO:0006807]; positive regulation of catalytic activity [GO:0043085] GO:0006807; GO:0016151; GO:0043085 41562 XM_044314268.1 0 7 1 0 0 NA NA NA NA NA NA 41563 XR_006396512.1 0 0 0 21 28 NA NA NA NA NA NA 41564 XM_044309537.1 3 0 3 6 14 NA NA NA NA NA NA 41565 XR_006396824.1 5 7 0 0 3 NA NA NA NA NA NA 41566 XM_029346236.2 115 78 30 72 83 Q7ZWI4 2.65e-24 GSK3-beta interaction protein (GSKIP) Danio rerio (Zebrafish) (Brachydanio rerio) regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of Wnt signaling pathway [GO:0030111] GO:0005737; GO:0019207; GO:0030111; GO:0051018; GO:0060828 41567 XM_044317611.1 0 2 0 13 16 NA NA NA NA NA NA 41568 XM_044311715.1 0 0 38 0 116 NA NA NA NA NA NA 41569 XM_044325761.1 98 22 19 61 40 NA NA NA NA NA NA 41570 XM_029331083.2 131 35 150 58 164 D3YXG0 1.94e-50 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 41571 XM_029331083.2 131 35 150 58 164 D3YXG0 1.35e-46 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 41572 XM_029331083.2 131 35 150 58 164 D3YXG0 4.44e-42 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 41573 XM_044323460.1 235 29 14 19 56 NA NA NA NA NA NA 41574 XM_044328033.1 4 0 7 21 0 Q90678 8.21e-79 Platelet-activating factor acetylhydrolase (PAF acetylhydrolase) (EC 3.1.1.47) (1-alkyl-2-acetylglycerophosphocholine esterase) (2-acetyl-1-alkylglycerophosphocholine esterase) (LDL-associated phospholipase A2) (LDL-PLA(2)) (PAF 2-acylhydrolase) Gallus gallus (Chicken) lipid catabolic process [GO:0016042] GO:0003847; GO:0005615; GO:0016042 41575 XR_006396850.1 36 45 52 39 156 NA NA NA NA NA NA 41576 XM_029337141.2 1330 1246 1080 1168 1630 Q863I2 0 Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress-responsive 1 protein) Sus scrofa (Pig) intracellular signal transduction [GO:0035556]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of T cell chemotaxis [GO:0010820]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468] GO:0000287; GO:0004674; GO:0005524; GO:0005737; GO:0005829; GO:0006468; GO:0010820; GO:0018107; GO:0035556; GO:0046777; GO:0106310; GO:1901017 41577 XM_044307364.1 6 0 0 0 4 NA NA NA NA NA NA 41578 XM_029332556.2 447 197 207 176 134 Q9NPJ8 2.7e-47 NTF2-related export protein 2 (Protein p15-2) Homo sapiens (Human) mRNA export from nucleus [GO:0006406]; nucleocytoplasmic transport [GO:0006913]; protein import into nucleus [GO:0006606] GO:0005634; GO:0005654; GO:0005829; GO:0006406; GO:0006606; GO:0006913; GO:0042272; GO:0044613; GO:0048471 41579 XR_003825836.2 301 97 69 75 123 NA NA NA NA NA NA 41580 XM_044324415.1 3 187 42 190 299 O75581 0 Low-density lipoprotein receptor-related protein 6 (LRP-6) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; chemical synaptic transmission [GO:0007268]; dopaminergic neuron differentiation [GO:0071542]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001933; GO:0005041; GO:0005102; GO:0005109; GO:0005576; GO:0005783; GO:0005886; GO:0006469; GO:0007204; GO:0007268; GO:0009986; GO:0014029; GO:0014033; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0031410; GO:0031901; GO:0034392; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043434; GO:0044335; GO:0044340; GO:0045121; GO:0045202; GO:0045787; GO:0045893; GO:0045944; GO:0051091; GO:0060070; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072659; GO:0090118; GO:0090244; GO:0098609; GO:1904928; GO:1904948; GO:1904953; GO:1990851; GO:1990909 41581 XM_044324415.1 3 187 42 190 299 O75581 2.97e-169 Low-density lipoprotein receptor-related protein 6 (LRP-6) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; chemical synaptic transmission [GO:0007268]; dopaminergic neuron differentiation [GO:0071542]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001933; GO:0005041; GO:0005102; GO:0005109; GO:0005576; GO:0005783; GO:0005886; GO:0006469; GO:0007204; GO:0007268; GO:0009986; GO:0014029; GO:0014033; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0031410; GO:0031901; GO:0034392; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043434; GO:0044335; GO:0044340; GO:0045121; GO:0045202; GO:0045787; GO:0045893; GO:0045944; GO:0051091; GO:0060070; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072659; GO:0090118; GO:0090244; GO:0098609; GO:1904928; GO:1904948; GO:1904953; GO:1990851; GO:1990909 41582 XM_044318155.1 2526 2297 975 2971 2142 O95721 3.61e-26 Synaptosomal-associated protein 29 (SNAP-29) (Soluble 29 kDa NSF attachment protein) (Vesicle-membrane fusion protein SNAP-29) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagosome membrane docking [GO:0016240]; cilium assembly [GO:0060271]; exocytosis [GO:0006887]; membrane fusion [GO:0061025]; protein transport [GO:0015031]; synaptic vesicle fusion to presynaptic active zone membrane [GO:0031629]; synaptic vesicle priming [GO:0016082]; vesicle fusion [GO:0006906]; vesicle targeting [GO:0006903] GO:0000139; GO:0000421; GO:0005484; GO:0005654; GO:0005737; GO:0005776; GO:0005813; GO:0005829; GO:0005886; GO:0006887; GO:0006903; GO:0006906; GO:0015031; GO:0016082; GO:0016240; GO:0019905; GO:0020018; GO:0031201; GO:0031629; GO:0035577; GO:0060271; GO:0061025; GO:0097352; GO:0098793 41583 XM_044312898.1 77 0 30 0 6 NA NA NA NA NA NA 41584 XM_029355067.2 15 0 1 0 10 NA NA NA NA NA NA 41585 XM_044320978.1 75 23 41 67 65 Q0ZDF7 5.27e-49 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase (OHCU decarboxylase) (EC 4.1.1.97) (Parahox neighbor) (Ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase) Amia calva (Bowfin) allantoin metabolic process [GO:0000255]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628] GO:0000255; GO:0005777; GO:0006144; GO:0019628; GO:0051997 41586 XM_044320121.1 0 0 0 11 5 NA NA NA NA NA NA 41587 XR_006392483.1 15 6 0 2 16 NA NA NA NA NA NA 41588 XM_029339706.2 1212 956 712 1003 826 Q91398 7.52e-131 Casein kinase II subunit beta (CK II beta) Danio rerio (Zebrafish) (Brachydanio rerio) regulation of protein serine/threonine phosphatase activity [GO:0080163]; Wnt signaling pathway [GO:0016055] GO:0005737; GO:0005956; GO:0016055; GO:0019887; GO:0046872; GO:0080163 41589 XM_044322189.1 0 0 0 0 35 NA NA NA NA NA NA 41590 XM_029340169.2 423 246 292 438 428 Q86VV8 2.97e-152 Rotatin Homo sapiens (Human) centriole replication [GO:0007099]; centriole-centriole cohesion [GO:0010457]; ciliary basal body organization [GO:0032053]; determination of left/right symmetry [GO:0007368] GO:0005737; GO:0005813; GO:0005814; GO:0007099; GO:0007368; GO:0010457; GO:0032053; GO:0036064 41591 XM_029340169.2 423 246 292 438 428 Q86VV8 3.5e-27 Rotatin Homo sapiens (Human) centriole replication [GO:0007099]; centriole-centriole cohesion [GO:0010457]; ciliary basal body organization [GO:0032053]; determination of left/right symmetry [GO:0007368] GO:0005737; GO:0005813; GO:0005814; GO:0007099; GO:0007368; GO:0010457; GO:0032053; GO:0036064 41592 XM_044328725.1 2122 2035 1487 4189 4055 A7S4N4 1.33e-129 Probable serine incorporator Nematostella vectensis (Starlet sea anemone) phospholipid biosynthetic process [GO:0008654] GO:0005789; GO:0008654; GO:0016020 41593 XM_044309066.1 631 618 510 542 641 NA NA NA NA NA NA 41594 XM_029351066.2 24 94 104 149 111 Q9VCY8 3.51e-93 Adiponectin receptor protein Drosophila melanogaster (Fruit fly) adiponectin-activated signaling pathway [GO:0033211]; fatty acid oxidation [GO:0019395]; female germ-line stem cell population maintenance [GO:0036099]; glucose homeostasis [GO:0042593]; hormone-mediated signaling pathway [GO:0009755]; positive regulation of insulin secretion [GO:0032024]; triglyceride homeostasis [GO:0070328] GO:0005886; GO:0009755; GO:0016020; GO:0016500; GO:0019395; GO:0032024; GO:0033211; GO:0036099; GO:0038023; GO:0042593; GO:0046872; GO:0070328 41595 XR_006398022.1 604 865 324 693 422 Q6MG77 4.13e-26 Decapping and exoribonuclease protein (DXO) (EC 3.6.1.-) (5'-3' exoribonuclease DXO) (EC 3.1.13.-) (Dom-3 homolog Z) (NAD-capped RNA hydrolase DXO) (DeNADding enzyme DXO) (EC 3.6.1.-) Rattus norvegicus (Rat) mRNA catabolic process [GO:0006402]; NAD-cap decapping [GO:0110155]; nuclear mRNA surveillance [GO:0071028]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; RNA destabilization [GO:0050779] GO:0000166; GO:0000287; GO:0000956; GO:0003729; GO:0005634; GO:0005654; GO:0005829; GO:0005886; GO:0006402; GO:0008409; GO:0034353; GO:0050779; GO:0071028; GO:0090305; GO:0110152; GO:0110155 41596 XR_006398022.1 604 865 324 693 422 Q6MG77 4.13e-26 Decapping and exoribonuclease protein (DXO) (EC 3.6.1.-) (5'-3' exoribonuclease DXO) (EC 3.1.13.-) (Dom-3 homolog Z) (NAD-capped RNA hydrolase DXO) (DeNADding enzyme DXO) (EC 3.6.1.-) Rattus norvegicus (Rat) mRNA catabolic process [GO:0006402]; NAD-cap decapping [GO:0110155]; nuclear mRNA surveillance [GO:0071028]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; RNA destabilization [GO:0050779] GO:0000166; GO:0000287; GO:0000956; GO:0003729; GO:0005634; GO:0005654; GO:0005829; GO:0005886; GO:0006402; GO:0008409; GO:0034353; GO:0050779; GO:0071028; GO:0090305; GO:0110152; GO:0110155 41597 XM_029331237.2 409 261 254 280 168 NA NA NA NA NA NA 41598 XM_029349117.2 635 845 351 513 407 NA NA NA NA NA NA 41599 XM_029325208.2 1539 1460 830 1043 752 NA NA NA NA NA NA 41600 XM_029354176.2 93 181 123 83 76 Q6P6Q6 5.91e-21 Transcription termination factor 3, mitochondrial (Mitochondrial transcription termination factor 3) (mTERF3) (mTERF domain-containing protein 1, mitochondrial) Rattus norvegicus (Rat) mitochondrial ribosome assembly [GO:0061668]; negative regulation of DNA-templated transcription [GO:0045892] GO:0000976; GO:0005739; GO:0045892; GO:0061668 41601 XM_029348934.2 43 0 0 0 57 P50571 1.05e-77 Gamma-aminobutyric acid receptor subunit beta-1 (GABA(A) receptor subunit beta-1) Mus musculus (Mouse) cellular response to histamine [GO:0071420]; central nervous system neuron development [GO:0021954]; chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid signaling pathway [GO:0007214]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; nervous system process [GO:0050877]; ovulation cycle [GO:0042698]; regulation of membrane potential [GO:0042391]; response to progesterone [GO:0032570]; response to toxic substance [GO:0009636]; signal transduction [GO:0007165] GO:0004890; GO:0005231; GO:0005253; GO:0005634; GO:0005635; GO:0005737; GO:0005886; GO:0006811; GO:0007165; GO:0007214; GO:0007268; GO:0009636; GO:0015276; GO:0016020; GO:0021954; GO:0022851; GO:0030425; GO:0030594; GO:0032570; GO:0034220; GO:0034707; GO:0042391; GO:0042698; GO:0043005; GO:0043235; GO:0045202; GO:0048787; GO:0050811; GO:0050877; GO:0071420; GO:0098685; GO:0098982; GO:0099507; GO:0099634; GO:0150047; GO:1902476; GO:1902711; GO:1904315 41602 XM_044318063.1 0 0 0 0 17 NA NA NA NA NA NA 41603 XM_044308599.1 14 0 10 40 19 NA NA NA NA NA NA 41604 XM_044316276.1 0 1 7 18 5 NA NA NA NA NA NA 41605 XM_029346945.2 1237 1685 736 853 440 NA NA NA NA NA NA 41606 XM_044317313.1 176 8 0 0 0 NA NA NA NA NA NA 41607 XM_044326167.1 54 43 5 9 9 NA NA NA NA NA NA 41608 XM_029337227.2 41 16 12 23 8 NA NA NA NA NA NA 41609 XR_006394499.1 26 12 17 27 27 NA NA NA NA NA NA 41610 XM_044313291.1 68 49 69 62 52 P51687 0 Sulfite oxidase, mitochondrial (EC 1.8.3.1) Homo sapiens (Human) sulfur compound metabolic process [GO:0006790] GO:0005739; GO:0005758; GO:0005759; GO:0006790; GO:0008482; GO:0020037; GO:0030151; GO:0043546 41611 XR_003826492.2 3 0 0 9 1 NA NA NA NA NA NA 41612 XR_003825722.2 141 240 374 168 282 NA NA NA NA NA NA 41613 XM_044311001.1 6 6 20 0 0 NA NA NA NA NA NA 41614 XM_029331215.2 222 90 191 139 219 Q9QX47 2.08e-43 Protein SON (Negative regulatory element-binding protein) (NRE-binding protein) Mus musculus (Mouse) microtubule cytoskeleton organization [GO:0000226]; mitotic cytokinesis [GO:0000281]; mRNA processing [GO:0006397]; negative regulation of apoptotic process [GO:0043066]; regulation of cell cycle [GO:0051726]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380] GO:0000226; GO:0000281; GO:0003677; GO:0003723; GO:0006397; GO:0008380; GO:0016607; GO:0043066; GO:0043484; GO:0048024; GO:0050733; GO:0051726 41615 XR_006392900.1 41 2 25 5 151 NA NA NA NA NA NA 41616 XM_044325921.1 189 0 0 71 0 A2RUV0 1.54e-147 Neurogenic locus notch homolog protein 1 (Notch 1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; cilium assembly [GO:0060271]; Notch signaling involved in heart development [GO:0061314]; regulation of developmental process [GO:0050793]; regulation of DNA-templated transcription [GO:0006355] GO:0001525; GO:0005509; GO:0005634; GO:0005886; GO:0006355; GO:0030154; GO:0038023; GO:0050793; GO:0060271; GO:0061314 41617 XM_044325921.1 189 0 0 71 0 A2RUV0 1.2e-140 Neurogenic locus notch homolog protein 1 (Notch 1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; cilium assembly [GO:0060271]; Notch signaling involved in heart development [GO:0061314]; regulation of developmental process [GO:0050793]; regulation of DNA-templated transcription [GO:0006355] GO:0001525; GO:0005509; GO:0005634; GO:0005886; GO:0006355; GO:0030154; GO:0038023; GO:0050793; GO:0060271; GO:0061314 41618 XM_044325921.1 189 0 0 71 0 A2RUV0 2.84e-138 Neurogenic locus notch homolog protein 1 (Notch 1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; cilium assembly [GO:0060271]; Notch signaling involved in heart development [GO:0061314]; regulation of developmental process [GO:0050793]; regulation of DNA-templated transcription [GO:0006355] GO:0001525; GO:0005509; GO:0005634; GO:0005886; GO:0006355; GO:0030154; GO:0038023; GO:0050793; GO:0060271; GO:0061314 41619 XM_044325921.1 189 0 0 71 0 A2RUV0 5.09e-137 Neurogenic locus notch homolog protein 1 (Notch 1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; cilium assembly [GO:0060271]; Notch signaling involved in heart development [GO:0061314]; regulation of developmental process [GO:0050793]; regulation of DNA-templated transcription [GO:0006355] GO:0001525; GO:0005509; GO:0005634; GO:0005886; GO:0006355; GO:0030154; GO:0038023; GO:0050793; GO:0060271; GO:0061314 41620 XM_044325921.1 189 0 0 71 0 A2RUV0 1.17e-134 Neurogenic locus notch homolog protein 1 (Notch 1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; cilium assembly [GO:0060271]; Notch signaling involved in heart development [GO:0061314]; regulation of developmental process [GO:0050793]; regulation of DNA-templated transcription [GO:0006355] GO:0001525; GO:0005509; GO:0005634; GO:0005886; GO:0006355; GO:0030154; GO:0038023; GO:0050793; GO:0060271; GO:0061314 41621 XM_044325921.1 189 0 0 71 0 A2RUV0 1.43e-111 Neurogenic locus notch homolog protein 1 (Notch 1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; cilium assembly [GO:0060271]; Notch signaling involved in heart development [GO:0061314]; regulation of developmental process [GO:0050793]; regulation of DNA-templated transcription [GO:0006355] GO:0001525; GO:0005509; GO:0005634; GO:0005886; GO:0006355; GO:0030154; GO:0038023; GO:0050793; GO:0060271; GO:0061314 41622 XM_044325921.1 189 0 0 71 0 A2RUV0 2.38e-90 Neurogenic locus notch homolog protein 1 (Notch 1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; cilium assembly [GO:0060271]; Notch signaling involved in heart development [GO:0061314]; regulation of developmental process [GO:0050793]; regulation of DNA-templated transcription [GO:0006355] GO:0001525; GO:0005509; GO:0005634; GO:0005886; GO:0006355; GO:0030154; GO:0038023; GO:0050793; GO:0060271; GO:0061314 41623 XM_044325921.1 189 0 0 71 0 A2RUV0 1.02e-85 Neurogenic locus notch homolog protein 1 (Notch 1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; cilium assembly [GO:0060271]; Notch signaling involved in heart development [GO:0061314]; regulation of developmental process [GO:0050793]; regulation of DNA-templated transcription [GO:0006355] GO:0001525; GO:0005509; GO:0005634; GO:0005886; GO:0006355; GO:0030154; GO:0038023; GO:0050793; GO:0060271; GO:0061314 41624 XM_029329312.2 55615 55576 34357 23385 19425 P78543 4.02e-23 Protein BTG2 (BTG family member 2) (NGF-inducible anti-proliferative protein PC3) Homo sapiens (Human) anterior/posterior pattern specification [GO:0009952]; associative learning [GO:0008306]; cellular response to DNA damage stimulus [GO:0006974]; central nervous system neuron development [GO:0021954]; dentate gyrus development [GO:0021542]; DNA repair [GO:0006281]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of translation [GO:0017148]; neuroblast proliferation [GO:0007405]; neuron projection development [GO:0031175]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; protein methylation [GO:0006479]; response to electrical stimulus [GO:0051602]; response to mechanical stimulus [GO:0009612]; response to organic cyclic compound [GO:0014070]; response to peptide hormone [GO:0043434]; skeletal muscle cell differentiation [GO:0035914] GO:0000122; GO:0003714; GO:0005634; GO:0005737; GO:0005829; GO:0006281; GO:0006479; GO:0006974; GO:0007405; GO:0007406; GO:0008285; GO:0008306; GO:0009612; GO:0009952; GO:0014070; GO:0017148; GO:0021542; GO:0021954; GO:0031175; GO:0035914; GO:0043434; GO:0043524; GO:0045930; GO:0051602; GO:0060213; GO:0070062 41625 XM_029335386.2 12 1 8 5 30 NA NA NA NA NA NA 41626 XM_044321202.1 2687 2932 1316 3179 1896 Q8BTV1 2.69e-141 Tumor suppressor candidate 3 (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TUSC3) (Oligosaccharyl transferase subunit TUSC3) (Magnesium uptake/transporter TUSC3) (Protein N33) Mus musculus (Mouse) cognition [GO:0050890]; magnesium ion transport [GO:0015693]; protein N-linked glycosylation via asparagine [GO:0018279] GO:0005739; GO:0008250; GO:0015095; GO:0015693; GO:0018279; GO:0050890; GO:0062062 41627 XM_044318526.1 459 379 92 545 450 Q7Z494 5.63e-50 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 41628 XM_044318526.1 459 379 92 545 450 Q7Z494 6.23e-49 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 41629 XM_044318526.1 459 379 92 545 450 Q7Z494 8.39e-44 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 41630 XM_044318526.1 459 379 92 545 450 Q7Z494 1.61e-37 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 41631 XM_029337205.2 68 0 0 0 0 NA NA NA NA NA NA 41632 XM_029332870.2 44026 40762 23215 48589 41741 B8VIX3 0 Uncharacterized skeletal organic matrix protein 6 (Uncharacterized SOMP-6) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 41633 XR_006396577.1 102 118 89 62 163 NA NA NA NA NA NA 41634 XR_003827275.2 51541 61064 75722 45711 28471 NA NA NA NA NA NA 41635 XM_044316198.1 35 0 24 0 0 NA NA NA NA NA NA 41636 XM_044321212.1 59 32 42 60 5 NA NA NA NA NA NA 41637 XM_044323422.1 1010 340 484 889 962 Q8NHU2 0 Cilia- and flagella-associated protein 61 Homo sapiens (Human) cilium movement [GO:0003341]; cilium organization [GO:0044782] GO:0003341; GO:0005930; GO:0031514; GO:0044782 41638 XM_044323422.1 1010 340 484 889 962 Q8NHU2 4.65e-69 Cilia- and flagella-associated protein 61 Homo sapiens (Human) cilium movement [GO:0003341]; cilium organization [GO:0044782] GO:0003341; GO:0005930; GO:0031514; GO:0044782 41639 XM_029329097.2 5180 2292 2068 4821 4241 NA NA NA NA NA NA 41640 XM_044317043.1 32 68 27 159 74 NA NA NA NA NA NA 41641 XM_044314617.1 143 4 19 11 207 NA NA NA NA NA NA 41642 XR_003827412.2 224 119 215 487 370 Q9HC58 2.58e-69 Sodium/potassium/calcium exchanger 3 (Na(+)/K(+)/Ca(2+)-exchange protein 3) (Solute carrier family 24 member 3) Homo sapiens (Human) bone mineralization [GO:0030282]; calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; ion transport [GO:0006811]; negative regulation of gene expression [GO:0010629]; positive regulation of gene expression [GO:0010628]; potassium ion transmembrane transport [GO:0071805]; sodium ion transmembrane transport [GO:0035725]; transport across blood-brain barrier [GO:0150104] GO:0005262; GO:0005886; GO:0006811; GO:0006874; GO:0008273; GO:0010628; GO:0010629; GO:0015293; GO:0030282; GO:0035725; GO:0070588; GO:0071805; GO:0071944; GO:0150104 41643 XR_003827412.2 224 119 215 487 370 Q9HC58 1.77e-21 Sodium/potassium/calcium exchanger 3 (Na(+)/K(+)/Ca(2+)-exchange protein 3) (Solute carrier family 24 member 3) Homo sapiens (Human) bone mineralization [GO:0030282]; calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; ion transport [GO:0006811]; negative regulation of gene expression [GO:0010629]; positive regulation of gene expression [GO:0010628]; potassium ion transmembrane transport [GO:0071805]; sodium ion transmembrane transport [GO:0035725]; transport across blood-brain barrier [GO:0150104] GO:0005262; GO:0005886; GO:0006811; GO:0006874; GO:0008273; GO:0010628; GO:0010629; GO:0015293; GO:0030282; GO:0035725; GO:0070588; GO:0071805; GO:0071944; GO:0150104 41644 XM_029336044.2 334 781 280 458 334 Q8K2J9 2.41e-62 BTB/POZ domain-containing protein 6 Mus musculus (Mouse) neurogenesis [GO:0022008] GO:0005829; GO:0022008 41645 XM_029331284.2 768 504 412 530 747 Q8N5D0 0 WD and tetratricopeptide repeats protein 1 Homo sapiens (Human) cellular chemical homeostasis [GO:0055082]; cellular response to insulin stimulus [GO:0032869]; glucose metabolic process [GO:0006006]; in utero embryonic development [GO:0001701]; multicellular organism growth [GO:0035264]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein ubiquitination [GO:0016567]; regulation of cell size [GO:0008361] GO:0000122; GO:0001701; GO:0004857; GO:0005654; GO:0005737; GO:0005829; GO:0006006; GO:0008361; GO:0016567; GO:0032869; GO:0035264; GO:0042393; GO:0042826; GO:0045717; GO:0055082; GO:0080008 41646 XM_029337841.2 67 34 61 255 75 O75762 2.85e-82 Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation-sensitive protein p120) (p120) (Wasabi receptor) Homo sapiens (Human) calcium ion transmembrane transport [GO:0070588]; cell surface receptor signaling pathway [GO:0007166]; cellular calcium ion homeostasis [GO:0006874]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to organic substance [GO:0071310]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; ion transport [GO:0006811]; protein homotetramerization [GO:0051289]; response to cold [GO:0009409]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; sensory perception of pain [GO:0019233]; thermoception [GO:0050955] GO:0005262; GO:0005886; GO:0006811; GO:0006874; GO:0007166; GO:0009409; GO:0009410; GO:0010033; GO:0014070; GO:0015267; GO:0015278; GO:0019233; GO:0032421; GO:0042802; GO:0048265; GO:0050955; GO:0050966; GO:0050968; GO:0051289; GO:0070301; GO:0070588; GO:0071310; GO:0097604 41647 XM_044320872.1 0 0 0 0 55 Q96PM5 2.63e-28 RING finger and CHY zinc finger domain-containing protein 1 (EC 2.3.2.27) (Androgen receptor N-terminal-interacting protein) (CH-rich-interacting match with PLAG1) (E3 ubiquitin-protein ligase Pirh2) (RING finger protein 199) (RING-type E3 ubiquitin transferase RCHY1) (Zinc finger protein 363) (p53-induced RING-H2 protein) (hPirh2) Homo sapiens (Human) error-free translesion synthesis [GO:0070987]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; protein autoubiquitination [GO:0051865]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000151; GO:0002039; GO:0004842; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006511; GO:0008270; GO:0016567; GO:0016607; GO:0031398; GO:0032436; GO:0042803; GO:0043231; GO:0051865; GO:0061630; GO:0070987 41648 XM_029334553.2 0 0 27 169 9 O00602 1.26e-53 Ficolin-1 (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin-alpha) (M-ficolin) Homo sapiens (Human) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation, lectin pathway [GO:0001867]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of viral entry into host cell [GO:0046597]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of opsonization [GO:1903028]; protein localization to cell surface [GO:0034394]; proteolysis [GO:0006508]; recognition of apoptotic cell [GO:0043654] GO:0001664; GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005576; GO:0005581; GO:0005615; GO:0006508; GO:0007186; GO:0009897; GO:0030246; GO:0031232; GO:0032757; GO:0033691; GO:0034394; GO:0034774; GO:0038187; GO:0043654; GO:0046597; GO:0046872; GO:0062023; GO:0097367; GO:1903028; GO:1904813; GO:1905370 41649 XM_044319709.1 66 75 48 0 0 Q54H46 9.94e-25 Probable serine/threonine-protein kinase drkA (EC 2.7.11.1) (Receptor-like kinase 1) (Receptor-like kinase A) (Vesicle-associated receptor tyrosine kinase-like protein 1) Dictyostelium discoideum (Social amoeba) receptor signaling pathway via STAT [GO:0097696]; signal transduction [GO:0007165] GO:0004672; GO:0004674; GO:0004713; GO:0005524; GO:0005737; GO:0007165; GO:0016020; GO:0097677; GO:0097696; GO:0106310 41650 XM_044307104.1 0 0 7 1 17 NA NA NA NA NA NA 41651 XM_029342887.2 922 652 549 996 1068 Q5S007 0 Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin) Homo sapiens (Human) autophagy [GO:0006914]; calcium-mediated signaling [GO:0019722]; canonical Wnt signaling pathway [GO:0060070]; cellular response to dopamine [GO:1903351]; cellular response to manganese ion [GO:0071287]; cellular response to organic cyclic compound [GO:0071407]; cellular response to oxidative stress [GO:0034599]; cellular response to starvation [GO:0009267]; determination of adult lifespan [GO:0008340]; endocytosis [GO:0006897]; endoplasmic reticulum organization [GO:0007029]; excitatory postsynaptic potential [GO:0060079]; exploration behavior [GO:0035640]; Golgi organization [GO:0007030]; GTP metabolic process [GO:0046039]; intracellular distribution of mitochondria [GO:0048312]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; locomotory exploration behavior [GO:0035641]; lysosome organization [GO:0007040]; MAPK cascade [GO:0000165]; mitochondrion localization [GO:0051646]; mitochondrion organization [GO:0007005]; negative regulation of autophagosome assembly [GO:1902902]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of GTPase activity [GO:0034260]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of late endosome to lysosome transport [GO:1902823]; negative regulation of macroautophagy [GO:0016242]; negative regulation of neuron death [GO:1901215]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein binding [GO:0032091]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein processing [GO:0010955]; negative regulation of protein processing involved in protein targeting to mitochondrion [GO:1903217]; negative regulation of protein targeting to mitochondrion [GO:1903215]; negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation [GO:1903125]; neuromuscular junction development [GO:0007528]; neuron death [GO:0070997]; neuron projection arborization [GO:0140058]; neuron projection morphogenesis [GO:0048812]; olfactory bulb development [GO:0021772]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; phosphorylation [GO:0016310]; positive regulation of autophagy [GO:0010508]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of dopamine receptor signaling pathway [GO:0060161]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of programmed cell death [GO:0043068]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein autoubiquitination [GO:1902499]; positive regulation of protein binding [GO:0032092]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; positive regulation of tumor necrosis factor production [GO:0032760]; protein autophosphorylation [GO:0046777]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein localization to endoplasmic reticulum exit site [GO:0070973]; protein localization to mitochondrion [GO:0070585]; protein phosphorylation [GO:0006468]; reactive oxygen species metabolic process [GO:0072593]; regulation of autophagy [GO:0010506]; regulation of branching morphogenesis of a nerve [GO:2000172]; regulation of CAMKK-AMPK signaling cascade [GO:1905289]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of dopamine receptor signaling pathway [GO:0060159]; regulation of ER to Golgi vesicle-mediated transport [GO:0060628]; regulation of kidney size [GO:0035564]; regulation of locomotion [GO:0040012]; regulation of lysosomal lumen pH [GO:0035751]; regulation of membrane potential [GO:0042391]; regulation of mitochondrial depolarization [GO:0051900]; regulation of mitochondrial fission [GO:0090140]; regulation of neuroblast proliferation [GO:1902692]; regulation of neuron death [GO:1901214]; regulation of neuron maturation [GO:0014041]; regulation of protein kinase A signaling [GO:0010738]; regulation of protein stability [GO:0031647]; regulation of retrograde transport, endosome to Golgi [GO:1905279]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of synaptic vesicle exocytosis [GO:2000300]; regulation of synaptic vesicle transport [GO:1902803]; response to oxidative stress [GO:0006979]; signal transduction [GO:0007165]; spermatogenesis [GO:0007283]; striatum development [GO:0021756]; tangential migration from the subventricular zone to the olfactory bulb [GO:0022028]; Wnt signalosome assembly [GO:1904887] GO:0000139; GO:0000149; GO:0000165; GO:0000287; GO:0001933; GO:0001934; GO:0003779; GO:0003924; GO:0004672; GO:0004674; GO:0004706; GO:0004709; GO:0004722; GO:0005096; GO:0005524; GO:0005525; GO:0005615; GO:0005737; GO:0005739; GO:0005741; GO:0005743; GO:0005759; GO:0005764; GO:0005768; GO:0005783; GO:0005789; GO:0005794; GO:0005798; GO:0005802; GO:0005829; GO:0005886; GO:0005902; GO:0006468; GO:0006606; GO:0006897; GO:0006914; GO:0006979; GO:0007005; GO:0007029; GO:0007030; GO:0007040; GO:0007165; GO:0007254; GO:0007283; GO:0007528; GO:0008017; GO:0008104; GO:0008340; GO:0009267; GO:0010506; GO:0010508; GO:0010738; GO:0010955; GO:0010977; GO:0014041; GO:0015631; GO:0016234; GO:0016242; GO:0016301; GO:0016310; GO:0017075; GO:0018105; GO:0018107; GO:0019722; GO:0021756; GO:0021772; GO:0022028; GO:0030159; GO:0030276; GO:0030424; GO:0030425; GO:0030426; GO:0030672; GO:0031267; GO:0031398; GO:0031410; GO:0031647; GO:0031966; GO:0032091; GO:0032092; GO:0032436; GO:0032473; GO:0032760; GO:0032839; GO:0034211; GO:0034260; GO:0034599; GO:0035556; GO:0035564; GO:0035640; GO:0035641; GO:0035751; GO:0036479; GO:0039706; GO:0040012; GO:0042391; GO:0042802; GO:0042803; GO:0043005; GO:0043025; GO:0043068; GO:0043195; GO:0043204; GO:0043231; GO:0043406; GO:0044325; GO:0044753; GO:0044754; GO:0045121; GO:0045860; GO:0046039; GO:0046777; GO:0048312; GO:0048812; GO:0051018; GO:0051646; GO:0051770; GO:0051900; GO:0051966; GO:0060070; GO:0060079; GO:0060159; GO:0060161; GO:0060628; GO:0060828; GO:0061001; GO:0070062; GO:0070585; GO:0070971; GO:0070973; GO:0070997; GO:0071287; GO:0071407; GO:0072593; GO:0090140; GO:0090263; GO:0090394; GO:0097487; GO:0098794; GO:0098978; GO:0099400; GO:0099523; GO:0106310; GO:0140058; GO:1900244; GO:1901214; GO:1901215; GO:1901727; GO:1902236; GO:1902499; GO:1902692; GO:1902803; GO:1902823; GO:1902902; GO:1903125; GO:1903206; GO:1903215; GO:1903217; GO:1903351; GO:1903980; GO:1904713; GO:1904887; GO:1905279; GO:1905289; GO:1990904; GO:1990909; GO:2000172; GO:2000300 41652 XM_044309912.1 217 45 134 112 143 NA NA NA NA NA NA 41653 XM_029344360.2 1115 1763 895 1406 2071 Q6NVY1 3.19e-144 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial (EC 3.1.2.4) (3-hydroxyisobutyryl-coenzyme A hydrolase) (HIB-CoA hydrolase) (HIBYL-CoA-H) Homo sapiens (Human) branched-chain amino acid catabolic process [GO:0009083]; valine catabolic process [GO:0006574] GO:0003860; GO:0005739; GO:0005759; GO:0006574; GO:0009083 41654 XM_044324728.1 8 2 31 36 31 NA NA NA NA NA NA 41655 XM_044308890.1 21 15 25 71 55 NA NA NA NA NA NA 41656 XR_006395229.1 449 492 145 307 146 NA NA NA NA NA NA 41657 XM_044315393.1 1127 1157 915 689 837 P15428 3.54e-53 15-hydroxyprostaglandin dehydrogenase [NAD(+)] (15-PGDH) (EC 1.1.1.141) (Eicosanoid/docosanoid dehydrogenase [NAD(+)]) (EC 1.1.1.-, EC 1.1.1.232) (Prostaglandin dehydrogenase 1) (Short chain dehydrogenase/reductase family 36C member 1) Homo sapiens (Human) ductus arteriosus closure [GO:0097070]; female pregnancy [GO:0007565]; kidney development [GO:0001822]; lipoxygenase pathway [GO:0019372]; negative regulation of cell cycle [GO:0045786]; ovulation [GO:0030728]; parturition [GO:0007567]; positive regulation of apoptotic process [GO:0043065]; positive regulation of vascular associated smooth muscle cell proliferation [GO:1904707]; prostaglandin metabolic process [GO:0006693]; regulation of prostaglandin catabolic process [GO:1905828]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; thrombin-activated receptor signaling pathway [GO:0070493]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001822; GO:0004957; GO:0005654; GO:0005737; GO:0005829; GO:0006693; GO:0007179; GO:0007565; GO:0007567; GO:0016323; GO:0016404; GO:0016616; GO:0019372; GO:0030728; GO:0032355; GO:0032496; GO:0042802; GO:0043065; GO:0045471; GO:0045786; GO:0051287; GO:0070062; GO:0070403; GO:0070493; GO:0097070; GO:1904707; GO:1905828 41658 XM_044315298.1 0 2 0 0 202 NA NA NA NA NA NA 41659 XM_044308668.1 0 0 0 8 13 O43422 8.84e-35 52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (Death-associated protein 4) (THAP domain-containing protein 0) (THAP domain-containing protein 12) Homo sapiens (Human) negative regulation of cell population proliferation [GO:0008285]; signal transduction [GO:0007165] GO:0003677; GO:0005634; GO:0007165; GO:0008285; GO:0046872; GO:0046983 41660 XM_029342712.2 1325 1163 661 1200 1804 P28288 0 ATP-binding cassette sub-family D member 3 (EC 3.1.2.-) (EC 7.6.2.-) (70 kDa peroxisomal membrane protein) (PMP70) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; bile acid biosynthetic process [GO:0006699]; fatty acid beta-oxidation [GO:0006635]; fatty acid biosynthetic process [GO:0006633]; long-chain fatty acid import into peroxisome [GO:0015910]; peroxisome organization [GO:0007031]; phytanic acid metabolic process [GO:1903512]; response to organic cyclic compound [GO:0014070]; response to xenobiotic stimulus [GO:0009410]; very long-chain fatty acid catabolic process [GO:0042760]; very long-chain fatty acid metabolic process [GO:0000038] GO:0000038; GO:0005324; GO:0005524; GO:0005739; GO:0005777; GO:0005778; GO:0005782; GO:0005829; GO:0006633; GO:0006635; GO:0006699; GO:0007031; GO:0009410; GO:0014070; GO:0015721; GO:0015910; GO:0016020; GO:0016887; GO:0042626; GO:0042760; GO:0042803; GO:0043231; GO:0043621; GO:0047617; GO:0140359; GO:1903512 41661 XM_044319835.1 1656 1919 1179 1140 747 Q6YP21 1.34e-154 Kynurenine--oxoglutarate transaminase 3 (EC 2.6.1.7) (Cysteine-S-conjugate beta-lyase 2) (EC 4.4.1.13) (Kynurenine aminotransferase 3) (Kynurenine aminotransferase III) (KATIII) (Kynurenine--glyoxylate transaminase) (EC 2.6.1.63) (Kynurenine--oxoglutarate transaminase III) Homo sapiens (Human) 2-oxoglutarate metabolic process [GO:0006103]; amino acid metabolic process [GO:0006520]; biosynthetic process [GO:0009058]; kynurenine metabolic process [GO:0070189]; L-kynurenine catabolic process [GO:0097053] GO:0003723; GO:0005737; GO:0005739; GO:0006103; GO:0006520; GO:0009058; GO:0016212; GO:0030170; GO:0042803; GO:0047315; GO:0047804; GO:0070189; GO:0097053 41662 XR_003824424.2 290 4 213 28 21 NA NA NA NA NA NA 41663 XR_006393439.1 0 19 0 0 0 Q9HAV4 3.85e-35 Exportin-5 (Exp5) (Ran-binding protein 21) Homo sapiens (Human) miRNA metabolic process [GO:0010586]; positive regulation of post-transcriptional gene silencing by RNA [GO:1900370]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; RNA export from nucleus [GO:0006405] GO:0000049; GO:0003723; GO:0003729; GO:0005049; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006405; GO:0006611; GO:0010586; GO:0016442; GO:0031267; GO:0035281; GO:0042565; GO:0070883; GO:1900370; GO:1905172 41664 XM_029334398.2 176 83 77 88 168 Q90Z12 4.86e-32 Transcription factor HES-4-A (Hairy and enhancer of split 4-A) (Protein hairy-2) (Xhairy2) (Protein hairy-2a) (Xhairy2a) Xenopus laevis (African clawed frog) BMP signaling pathway [GO:0030509]; floor plate development [GO:0033504]; lens development in camera-type eye [GO:0002088]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural crest formation [GO:0014029]; prechordal plate formation [GO:0021501] GO:0000122; GO:0002088; GO:0005634; GO:0014029; GO:0021501; GO:0030509; GO:0033504; GO:0043066; GO:0043425; GO:0043565; GO:0045892; GO:0046983 41665 XM_029349487.2 4009 2431 2057 3498 3046 Q6XUZ5 0 Isocitrate dehydrogenase [NADP] cytoplasmic (IDH) (IDH1) (EC 1.1.1.42) (Cytosolic NADP-isocitrate dehydrogenase) (IDPc) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase) Ovis aries (Sheep) 2-oxoglutarate metabolic process [GO:0006103]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; tricarboxylic acid cycle [GO:0006099] GO:0000287; GO:0004450; GO:0005829; GO:0006097; GO:0006099; GO:0006102; GO:0006103; GO:0051287 41666 XM_029332176.2 1914 1771 1620 2986 2871 NA NA NA NA NA NA 41667 XM_044317810.1 61 0 0 75 0 Q9H773 1.2e-53 dCTP pyrophosphatase 1 (EC 3.6.1.12) (Deoxycytidine-triphosphatase 1) (dCTPase 1) (RS21C6) (XTP3-transactivated gene A protein) Homo sapiens (Human) dCTP catabolic process [GO:0006253]; DNA protection [GO:0042262]; nucleoside triphosphate catabolic process [GO:0009143] GO:0000287; GO:0005634; GO:0005654; GO:0005739; GO:0005829; GO:0006253; GO:0009143; GO:0032556; GO:0042262; GO:0042802; GO:0047429; GO:0047840 41668 XM_029344681.2 122 200 24 15 55 Q9CYL5 1.95e-24 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Mus musculus (Mouse) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070374 41669 XM_044319600.1 59 1 39 108 45 NA NA NA NA NA NA 41670 XM_044327698.1 403 2 158 5 53 NA NA NA NA NA NA 41671 XR_006397512.1 0 0 2 0 6 NA NA NA NA NA NA 41672 XM_029338439.2 676 673 349 580 876 Q6GNG8 8.79e-35 PRKR-interacting protein 1 homolog Xenopus laevis (African clawed frog) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0003725; GO:0005681; GO:0005730; GO:0006397; GO:0008380 41673 XM_044306883.1 5 3 0 0 22 NA NA NA NA NA NA 41674 XM_029351357.2 0 33 0 0 0 NA NA NA NA NA NA 41675 XM_029358674.2 0 0 8 0 0 NA NA NA NA NA NA 41676 XM_029349807.2 0 4 5 21 19 NA NA NA NA NA NA 41677 XR_006395013.1 74 37 20 58 112 NA NA NA NA NA NA 41678 XM_044308554.1 41 0 0 0 0 Q5U378 7.89e-98 Tubulin-specific chaperone E (Tubulin-folding cofactor E) Danio rerio (Zebrafish) (Brachydanio rerio) microtubule cytoskeleton organization [GO:0000226]; post-chaperonin tubulin folding pathway [GO:0007023]; tubulin complex assembly [GO:0007021] GO:0000226; GO:0005737; GO:0005856; GO:0007021; GO:0007023; GO:0043014 41679 XR_006393466.1 0 0 11 0 0 NA NA NA NA NA NA 41680 XM_029357593.2 8 0 39 0 0 Q61818 3.18e-21 Retinoic acid-induced protein 1 Mus musculus (Mouse) circadian regulation of gene expression [GO:0032922]; negative regulation of multicellular organism growth [GO:0040015]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal system development [GO:0001501] GO:0001501; GO:0005634; GO:0005654; GO:0005737; GO:0006357; GO:0032922; GO:0040015; GO:0045893; GO:0046872 41681 XM_029345321.2 914 650 746 925 954 P91119 0 Probable 3',5'-cyclic phosphodiesterase pde-5 (EC 3.1.4.17) Caenorhabditis elegans chemosensory behavior [GO:0007635]; chemotaxis [GO:0006935]; determination of adult lifespan [GO:0008340]; microvillus organization [GO:0032528]; negative regulation of cGMP-mediated signaling [GO:0010754]; phototransduction [GO:0007602]; positive regulation of gene expression [GO:0010628]; response to alkaline pH [GO:0010446]; response to hydrogen peroxide [GO:0042542]; signal transduction [GO:0007165] GO:0004114; GO:0004118; GO:0006935; GO:0007165; GO:0007602; GO:0007635; GO:0008340; GO:0010446; GO:0010628; GO:0010754; GO:0032528; GO:0042542; GO:0046872; GO:0047555 41682 XM_029346136.2 0 0 376 183 140 NA NA NA NA NA NA 41683 XM_044310109.1 245 37 61 455 227 NA NA NA NA NA NA 41684 XM_029327769.2 1442 2912 1727 4785 2655 NA NA NA NA NA NA 41685 XM_044321762.1 2439 2609 1883 3106 2988 O57656 2.14e-130 Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic (GPD-C) (GPDH-C) (EC 1.1.1.8) Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate catabolic process [GO:0046168] GO:0005975; GO:0009331; GO:0042803; GO:0046168; GO:0047952; GO:0051287 41686 XM_029343706.2 241 0 0 118 107 NA NA NA NA NA NA 41687 XM_044307160.1 0 0 8 0 58 Q91ZQ5 1.38e-99 Retinoid isomerohydrolase (EC 3.1.1.64) (All-trans-retinyl-palmitate hydrolase) (Lutein isomerase) (Meso-zeaxanthin isomerase) (EC 5.3.3.22) (Retinal pigment epithelium-specific 65 kDa protein) (Retinol isomerase) Mus musculus (Mouse) cellular response to electrical stimulus [GO:0071257]; circadian rhythm [GO:0007623]; detection of light stimulus involved in visual perception [GO:0050908]; insulin receptor signaling pathway [GO:0008286]; neural retina development [GO:0003407]; regulation of gene expression [GO:0010468]; retina development in camera-type eye [GO:0060041]; retina homeostasis [GO:0001895]; retina morphogenesis in camera-type eye [GO:0060042]; retinal metabolic process [GO:0042574]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; visual perception [GO:0007601]; zeaxanthin biosynthetic process [GO:1901827] GO:0001523; GO:0001786; GO:0001895; GO:0003407; GO:0005634; GO:0005737; GO:0005789; GO:0005886; GO:0007601; GO:0007623; GO:0008286; GO:0010468; GO:0016020; GO:0016702; GO:0016853; GO:0031210; GO:0042572; GO:0042574; GO:0044297; GO:0046872; GO:0050251; GO:0050908; GO:0052884; GO:0052885; GO:0060041; GO:0060042; GO:0071257; GO:1901612; GO:1901827 41688 XM_029339631.2 0 0 0 0 398 Q8IUR5 0 Protein O-mannosyl-transferase TMTC1 (EC 2.4.1.109) (Transmembrane and TPR repeat-containing protein 1) Homo sapiens (Human) protein O-linked mannosylation [GO:0035269]; RNA processing [GO:0006396] GO:0000030; GO:0004169; GO:0005783; GO:0006396; GO:0016020; GO:0035269 41689 XM_044329312.1 308 154 177 213 338 NA NA NA NA NA NA 41690 XM_029347241.2 1527 2211 1720 3060 704 P62861 5.47e-52 FAU ubiquitin-like and ribosomal protein S30 [Cleaved into: Ubiquitin-like protein FUBI; 40S ribosomal protein S30 (Small ribosomal subunit protein eS30)] Homo sapiens (Human) antibacterial humoral response [GO:0019731]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cytoplasmic translation [GO:0002181]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response in mucosa [GO:0002227]; ribosomal small subunit assembly [GO:0000028]; translation [GO:0006412] GO:0000028; GO:0002181; GO:0002227; GO:0003723; GO:0003735; GO:0005615; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006412; GO:0015935; GO:0019731; GO:0022626; GO:0022627; GO:0050830; GO:0061844 41691 XM_029339437.2 1308 983 513 1012 129 NA NA NA NA NA NA 41692 XM_029338504.2 1038 681 628 1212 1197 E9PVA8 0 eIF-2-alpha kinase activator GCN1 (GCN1 eIF-2-alpha kinase activator homolog) (GCN1-like protein 1) (General control of amino-acid synthesis 1-like protein 1) (Translational activator GCN1) Mus musculus (Mouse) cellular response to amino acid starvation [GO:0034198]; cellular response to leucine starvation [GO:1990253]; regulation of translation [GO:0006417] GO:0005829; GO:0005844; GO:0006417; GO:0008494; GO:0019887; GO:0034198; GO:1990253 41693 XM_029344745.2 842 134 234 433 1330 O54975 2.38e-169 Xaa-Pro aminopeptidase 1 (EC 3.4.11.9) (Aminoacylproline aminopeptidase) (Cytosolic aminopeptidase P) (Soluble aminopeptidase P) (sAmp) (X-Pro aminopeptidase 1) (X-prolyl aminopeptidase 1, soluble) Rattus norvegicus (Rat) bradykinin catabolic process [GO:0010815]; proteolysis [GO:0006508] GO:0004177; GO:0005737; GO:0005829; GO:0006508; GO:0010815; GO:0030145; GO:0042803; GO:0070006 41694 XM_029330588.2 3963 3486 1621 2658 1865 NA NA NA NA NA NA 41695 XM_044320637.1 0 0 62 50 0 NA NA NA NA NA NA 41696 XM_029346169.2 15 1 24 5 133 O75762 1.5e-60 Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation-sensitive protein p120) (p120) (Wasabi receptor) Homo sapiens (Human) calcium ion transmembrane transport [GO:0070588]; cell surface receptor signaling pathway [GO:0007166]; cellular calcium ion homeostasis [GO:0006874]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to organic substance [GO:0071310]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; ion transport [GO:0006811]; protein homotetramerization [GO:0051289]; response to cold [GO:0009409]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; sensory perception of pain [GO:0019233]; thermoception [GO:0050955] GO:0005262; GO:0005886; GO:0006811; GO:0006874; GO:0007166; GO:0009409; GO:0009410; GO:0010033; GO:0014070; GO:0015267; GO:0015278; GO:0019233; GO:0032421; GO:0042802; GO:0048265; GO:0050955; GO:0050966; GO:0050968; GO:0051289; GO:0070301; GO:0070588; GO:0071310; GO:0097604 41697 XM_029346169.2 15 1 24 5 133 O75762 3.1e-48 Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation-sensitive protein p120) (p120) (Wasabi receptor) Homo sapiens (Human) calcium ion transmembrane transport [GO:0070588]; cell surface receptor signaling pathway [GO:0007166]; cellular calcium ion homeostasis [GO:0006874]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to organic substance [GO:0071310]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; ion transport [GO:0006811]; protein homotetramerization [GO:0051289]; response to cold [GO:0009409]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; sensory perception of pain [GO:0019233]; thermoception [GO:0050955] GO:0005262; GO:0005886; GO:0006811; GO:0006874; GO:0007166; GO:0009409; GO:0009410; GO:0010033; GO:0014070; GO:0015267; GO:0015278; GO:0019233; GO:0032421; GO:0042802; GO:0048265; GO:0050955; GO:0050966; GO:0050968; GO:0051289; GO:0070301; GO:0070588; GO:0071310; GO:0097604 41698 XM_029344553.2 307 316 114 181 247 NA NA NA NA NA NA 41699 XM_044315452.1 7 0 0 5 4 NA NA NA NA NA NA 41700 XM_029334685.2 11926 12190 9395 14786 13500 P35213 4.29e-82 14-3-3 protein beta/alpha (Prepronerve growth factor RNH-1) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed] Rattus norvegicus (Rat) cytoplasmic sequestering of protein [GO:0051220]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; negative regulation of protein dephosphorylation [GO:0035308]; positive regulation of catalytic activity [GO:0043085]; protein targeting [GO:0006605]; signal transduction [GO:0007165] GO:0004860; GO:0005634; GO:0005737; GO:0005829; GO:0006605; GO:0007165; GO:0008022; GO:0017053; GO:0019899; GO:0019904; GO:0032991; GO:0035308; GO:0042470; GO:0042802; GO:0042826; GO:0043085; GO:0044877; GO:0045744; GO:0045892; GO:0048471; GO:0050815; GO:0051219; GO:0051220 41701 XM_044325821.1 32 0 53 25 190 NA NA NA NA NA NA 41702 XM_044307049.1 0 0 4 0 10 NA NA NA NA NA NA 41703 XM_044326608.1 0 0 23 75 0 O18276 4.68e-60 Gamma-aminobutyric acid receptor subunit beta (GABA(A) receptor subunit beta) Caenorhabditis elegans chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165] GO:0004890; GO:0005230; GO:0005231; GO:0005254; GO:0005886; GO:0006811; GO:0007165; GO:0007268; GO:0030594; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:1902476; GO:1902711; GO:1904315 41704 XM_044328994.1 8 6 0 17 0 F1R332 1.84e-24 Galanin receptor 2a Danio rerio (Zebrafish) (Brachydanio rerio) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; neuropeptide signaling pathway [GO:0007218] GO:0004966; GO:0005886; GO:0007188; GO:0007218; GO:0008528 41705 XM_029332421.2 0 0 7 5 19 Q6Q0C0 1.03e-71 E3 ubiquitin-protein ligase TRAF7 (EC 2.3.2.27) (RING finger and WD repeat-containing protein 1) (RING finger protein 119) (RING-type E3 ubiquitin transferase TRAF7) (TNF receptor-associated factor 7) Homo sapiens (Human) apoptotic process [GO:0006915]; Notch signaling pathway [GO:0007219]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of MAPK cascade [GO:0043410]; protein ubiquitination [GO:0016567]; regulation of ERK1 and ERK2 cascade [GO:0070372]; ribosomal large subunit assembly [GO:0000027] GO:0000027; GO:0000151; GO:0004842; GO:0005730; GO:0005886; GO:0006915; GO:0007219; GO:0008270; GO:0016567; GO:0031410; GO:0043231; GO:0043410; GO:0070372; GO:2001235 41706 XM_029352962.2 75 67 27 8 64 NA NA NA NA NA NA 41707 XR_006391615.1 3245 2668 1108 2179 2235 NA NA NA NA NA NA 41708 XM_044328879.1 25 41 0 57 11 Q6L8S8 9.09e-60 Beta-1,4-N-acetylgalactosaminyltransferase 3 (Beta4GalNAc-T3) (Beta4GalNAcT3) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase III) (N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 2) (NGalNAc-T2) Mus musculus (Mouse) chondroitin sulfate biosynthetic process [GO:0030206] GO:0005794; GO:0008376; GO:0030206; GO:0032580; GO:0033842; GO:0043231; GO:0047238 41709 XM_029337873.2 1217 965 854 858 1057 Q5RDT5 1.09e-56 Histone deacetylase complex subunit SAP18 (18 kDa Sin3-associated polypeptide) (Sin3-associated polypeptide p18) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) mRNA processing [GO:0006397]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of apoptotic process [GO:0043065]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380] GO:0000381; GO:0003714; GO:0005829; GO:0006397; GO:0008380; GO:0016607; GO:0035145; GO:0043065; GO:0048025; GO:0061574 41710 XM_029353494.2 0 29 0 30 28 NA NA NA NA NA NA 41711 XM_044313620.1 132 155 150 140 186 NA NA NA NA NA NA 41712 XR_003824409.2 457 423 443 706 95 NA NA NA NA NA NA 41713 XM_029337123.2 687 204 227 619 534 NA NA NA NA NA NA 41714 XM_044319429.1 22 44 39 68 148 P71359 6.32e-25 ATP-dependent DNA helicase RecQ (EC 3.6.4.12) Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; SOS response [GO:0009432] GO:0003677; GO:0005524; GO:0005694; GO:0005737; GO:0006260; GO:0006281; GO:0006310; GO:0009378; GO:0009432; GO:0016887; GO:0030894; GO:0032508; GO:0043138; GO:0043590 41715 XM_029337248.1 4407 6 6 2345 14 NA NA NA NA NA NA 41716 XM_029350460.2 29 4 10 15 71 NA NA NA NA NA NA 41717 XM_029341643.2 504 291 327 211 814 O15040 1.21e-61 Tectonin beta-propeller repeat-containing protein 2 (WD repeat-containing protein KIAA0329/KIAA0297) Homo sapiens (Human) autophagy [GO:0006914]; protein exit from endoplasmic reticulum [GO:0032527] GO:0005737; GO:0006914; GO:0032527 41718 XM_029341643.2 504 291 327 211 814 O15040 3.57e-37 Tectonin beta-propeller repeat-containing protein 2 (WD repeat-containing protein KIAA0329/KIAA0297) Homo sapiens (Human) autophagy [GO:0006914]; protein exit from endoplasmic reticulum [GO:0032527] GO:0005737; GO:0006914; GO:0032527 41719 XR_006395846.1 25 41 24 10 35 NA NA NA NA NA NA 41720 XM_044318871.1 619 802 518 1010 447 Q9BSW2 5.19e-55 EF-hand calcium-binding domain-containing protein 4B (Calcium release-activated calcium channel regulator 2A) (CRAC channel regulator 2A) (Calcium release-activated channel regulator 2A) (Ras-related protein Rab-46) Homo sapiens (Human) activation of store-operated calcium channel activity [GO:0032237]; endosomal transport [GO:0016197]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of JNK cascade [GO:0046330]; response to histamine [GO:0034776]; store-operated calcium entry [GO:0002115]; T-helper 1 cell differentiation [GO:0045063] GO:0000139; GO:0001772; GO:0002115; GO:0003924; GO:0005509; GO:0005525; GO:0005576; GO:0005737; GO:0005815; GO:0005886; GO:0016020; GO:0016197; GO:0031982; GO:0032237; GO:0032588; GO:0033093; GO:0034776; GO:0035580; GO:0045063; GO:0046330; GO:0051928 41721 XM_044318871.1 619 802 518 1010 447 Q9BSW2 1.12e-35 EF-hand calcium-binding domain-containing protein 4B (Calcium release-activated calcium channel regulator 2A) (CRAC channel regulator 2A) (Calcium release-activated channel regulator 2A) (Ras-related protein Rab-46) Homo sapiens (Human) activation of store-operated calcium channel activity [GO:0032237]; endosomal transport [GO:0016197]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of JNK cascade [GO:0046330]; response to histamine [GO:0034776]; store-operated calcium entry [GO:0002115]; T-helper 1 cell differentiation [GO:0045063] GO:0000139; GO:0001772; GO:0002115; GO:0003924; GO:0005509; GO:0005525; GO:0005576; GO:0005737; GO:0005815; GO:0005886; GO:0016020; GO:0016197; GO:0031982; GO:0032237; GO:0032588; GO:0033093; GO:0034776; GO:0035580; GO:0045063; GO:0046330; GO:0051928 41722 XM_029345587.2 10 19 18 12 47 NA NA NA NA NA NA 41723 XM_044325815.1 92 20 92 64 250 P81274 4.02e-47 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 41724 XM_044325815.1 92 20 92 64 250 P81274 2.43e-40 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 41725 XM_044325815.1 92 20 92 64 250 P81274 1.13e-36 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 41726 XM_044325815.1 92 20 92 64 250 P81274 3.11e-32 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 41727 XM_044314474.1 4 97 16 134 10 NA NA NA NA NA NA 41728 XM_029342144.2 0 14 51 13 49 Q3UFB2 1.86e-48 Box C/D snoRNA protein 1 (Zinc finger HIT domain-containing protein 6) Mus musculus (Mouse) box C/D snoRNP assembly [GO:0000492]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; protein complex oligomerization [GO:0051259]; snoRNA localization [GO:0048254] GO:0000463; GO:0000492; GO:0001094; GO:0005634; GO:0019899; GO:0042802; GO:0046872; GO:0048254; GO:0051117; GO:0051259; GO:0070761 41729 XM_044323339.1 24 40 0 42 0 B8V7S0 1.77e-69 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 41730 XM_044307197.1 686 552 523 268 457 NA NA NA NA NA NA 41731 XM_029330831.2 2275 1775 973 2034 1697 Q9VXE5 7.33e-143 Serine/threonine-protein kinase PAK mbt (EC 2.7.11.1) (Protein mushroom bodies tiny) (p21-activated kinase-related protein) Drosophila melanogaster (Fruit fly) compound eye development [GO:0048749]; compound eye photoreceptor cell differentiation [GO:0001751]; cytoskeleton organization [GO:0007010]; Golgi organization [GO:0007030]; intracellular signal transduction [GO:0035556]; mushroom body development [GO:0016319]; negative regulation of cell size [GO:0045792]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of compound eye photoreceptor development [GO:0045315]; positive regulation of developmental growth [GO:0048639]; protein phosphorylation [GO:0006468]; regulation of cell-cell adhesion mediated by cadherin [GO:2000047]; regulation of MAPK cascade [GO:0043408] GO:0001751; GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0005886; GO:0005912; GO:0006468; GO:0007010; GO:0007030; GO:0016319; GO:0018105; GO:0031267; GO:0035556; GO:0043408; GO:0045315; GO:0045792; GO:0048639; GO:0048749; GO:0106310; GO:2000047 41732 XM_029335582.2 104 237 85 107 123 NA NA NA NA NA NA 41733 XM_029356679.2 1521 1379 1010 1717 1764 NA NA NA NA NA NA 41734 XM_044309047.1 4125 5286 2508 2973 3308 Q7Z7E8 6.43e-35 Ubiquitin-conjugating enzyme E2 Q1 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme Q1) (Protein NICE-5) (Ubiquitin carrier protein Q1) (Ubiquitin-protein ligase Q1) Homo sapiens (Human) embryo implantation [GO:0007566]; fertilization [GO:0009566]; mating behavior [GO:0007617]; prolactin secretion [GO:0070459]; protein polyubiquitination [GO:0000209]; reproductive system development [GO:0061458]; suckling behavior [GO:0001967] GO:0000209; GO:0001967; GO:0005524; GO:0005634; GO:0005829; GO:0007566; GO:0007617; GO:0009566; GO:0030175; GO:0061458; GO:0061631; GO:0070459 41735 XM_044315066.1 990 921 672 789 1059 Q969X5 5.66e-133 Endoplasmic reticulum-Golgi intermediate compartment protein 1 (ER-Golgi intermediate compartment 32 kDa protein) (ERGIC-32) Homo sapiens (Human) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] GO:0000139; GO:0005654; GO:0005783; GO:0005789; GO:0005793; GO:0006888; GO:0006890; GO:0016020; GO:0030134; GO:0033116; GO:0043231 41736 XM_029348317.2 9 2 0 9 13 NA NA NA NA NA NA 41737 XM_029340932.2 326 465 125 244 344 Q5XI57 1.92e-107 Protein polyglycylase TTLL10 (EC 6.3.2.-) (Tubulin--tyrosine ligase-like protein 10) Rattus norvegicus (Rat) protein polyglycylation [GO:0018094] GO:0005524; GO:0005874; GO:0005929; GO:0005930; GO:0015630; GO:0018094; GO:0046872; GO:0070735; GO:0070737 41738 XM_029340950.2 496 525 278 705 630 Q801D8 3.97e-25 Membrane progestin receptor alpha (mPR alpha) (Membrane progesterone receptor) Cynoscion nebulosus (Spotted seatrout) (Otolithus nebulosus) oogenesis [GO:0048477] GO:0005496; GO:0005886; GO:0048477 41739 XM_044320435.1 28 46 7 64 16 NA NA NA NA NA NA 41740 XR_006394999.1 99 141 206 154 328 NA NA NA NA NA NA 41741 XM_044308481.1 21 7 2 20 25 NA NA NA NA NA NA 41742 XM_029334588.2 251 0 0 494 143 Q9UKP5 1.05e-123 A disintegrin and metalloproteinase with thrombospondin motifs 6 (ADAM-TS 6) (ADAM-TS6) (ADAMTS-6) (EC 3.4.24.-) Homo sapiens (Human) aorta development [GO:0035904]; cardiac septum development [GO:0003279]; coronary vasculature development [GO:0060976]; extracellular matrix organization [GO:0030198]; kidney development [GO:0001822]; proteolysis [GO:0006508] GO:0001822; GO:0003279; GO:0004222; GO:0005576; GO:0006508; GO:0008237; GO:0030198; GO:0031012; GO:0035904; GO:0046872; GO:0060976 41743 XM_044307803.1 143 44 39 118 117 NA NA NA NA NA NA 41744 XR_006394250.1 0 7 3 0 15 NA NA NA NA NA NA 41745 XM_029357882.2 188 137 220 230 159 Q4R3Y4 0 Long-chain fatty acid transport protein 4 (FATP-4) (Fatty acid transport protein 4) (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Solute carrier family 27 member 4) (Very long-chain acyl-CoA synthetase 4) (ACSVL4) (EC 6.2.1.-) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0000166; GO:0005789; GO:0047676; GO:1901480 41746 XM_029345203.2 2030 1221 535 1481 1311 NA NA NA NA NA NA 41747 XM_029329402.2 1899 1492 695 981 615 A5PK16 2.46e-131 Cyclin-F Bos taurus (Bovine) cell cycle [GO:0007049]; cell division [GO:0051301]; negative regulation of centrosome duplication [GO:0010826]; protein ubiquitination [GO:0016567]; regulation of cell cycle [GO:0051726]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0005634; GO:0005814; GO:0007049; GO:0010826; GO:0016567; GO:0019005; GO:0031146; GO:0048471; GO:0051301; GO:0051726 41748 XM_044318780.1 387 0 0 0 0 NA NA NA NA NA NA 41749 XR_006398011.1 232 205 166 184 25 NA NA NA NA NA NA 41750 XM_029327364.2 308 168 108 168 167 NA NA NA NA NA NA 41751 XM_029338472.2 9113 10056 4131 8269 8165 P23403 2.71e-59 40S ribosomal protein S20 (S22) Xenopus laevis (African clawed frog) translation [GO:0006412] GO:0003723; GO:0003735; GO:0005737; GO:0006412; GO:0015935 41752 XM_044306851.1 200 48 13 140 6 NA NA NA NA NA NA 41753 XM_044312766.1 402 83 470 828 285 Q8K4Q6 8.34e-95 Endonuclease 8-like 1 (EC 3.2.2.-) (EC 4.2.99.18) (DNA glycosylase/AP lyase Neil1) (DNA-(apurinic or apyrimidinic site) lyase Neil1) (Endonuclease VIII-like 1) (Nei homolog 1) (NEH1) (Nei-like protein 1) Mus musculus (Mouse) base-excision repair [GO:0006284]; DNA repair [GO:0006281]; negative regulation of nuclease activity [GO:0032074]; response to oxidative stress [GO:0006979] GO:0003684; GO:0003906; GO:0005634; GO:0005654; GO:0005694; GO:0005737; GO:0005815; GO:0006281; GO:0006284; GO:0006979; GO:0008022; GO:0008270; GO:0016798; GO:0016829; GO:0019104; GO:0032074; GO:0140078 41754 XM_044327629.1 14 2 29 21 31 NA NA NA NA NA NA 41755 XM_029333173.2 790 546 709 1080 1190 Q3TCX3 5.97e-67 KH homology domain-containing protein 4 (Brings lots of money 7) (Pre-mRNA splicing factor protein Khdc4) Mus musculus (Mouse) mRNA splice site selection [GO:0006376] GO:0003723; GO:0005634; GO:0005654; GO:0005681; GO:0005737; GO:0006376 41756 XR_003826030.2 185 200 154 179 149 NA NA NA NA NA NA 41757 XM_029342978.2 2 13 84 6 7 Q80XJ3 4.89e-64 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 41758 XM_029342978.2 2 13 84 6 7 Q80XJ3 1.12e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 41759 XM_029342978.2 2 13 84 6 7 Q80XJ3 1.99e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 41760 XM_029342978.2 2 13 84 6 7 Q80XJ3 9.67e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 41761 XM_029342978.2 2 13 84 6 7 Q80XJ3 8.67e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 41762 XM_029342978.2 2 13 84 6 7 Q80XJ3 1.47e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 41763 XM_029342978.2 2 13 84 6 7 Q80XJ3 1.8e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 41764 XM_029342978.2 2 13 84 6 7 Q80XJ3 2e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 41765 XM_044308246.1 107 0 9 125 5 Q8CGZ0 2.55e-31 Calcium homeostasis endoplasmic reticulum protein (SR-related CTD-associated factor 6) Mus musculus (Mouse) cellular calcium ion homeostasis [GO:0006874]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; release of sequestered calcium ion into cytosol [GO:0051209]; RNA processing [GO:0006396] GO:0003723; GO:0005737; GO:0006396; GO:0006874; GO:0008285; GO:0033017; GO:0044325; GO:0048471; GO:0051209; GO:0070886 41766 XM_044325211.1 28 67 0 56 25 NA NA NA NA NA NA 41767 XM_029346078.2 456 1164 255 750 448 NA NA NA NA NA NA 41768 XR_003822985.2 2 0 0 3 10 NA NA NA NA NA NA 41769 XM_044318417.1 4 42 1 8 3 NA NA NA NA NA NA 41770 XM_044316595.1 319 0 0 0 143 Q8BWC0 2.4e-161 Two pore channel protein 2 (Two pore calcium channel protein 2) (Voltage-dependent calcium channel protein TPC2) Mus musculus (Mouse) calcium-mediated signaling [GO:0019722]; cellular calcium ion homeostasis [GO:0006874]; endocytosis involved in viral entry into host cell [GO:0075509]; endosome to lysosome transport of low-density lipoprotein particle [GO:0090117]; intracellular pH reduction [GO:0051452]; lysosome organization [GO:0007040]; negative regulation of developmental pigmentation [GO:0048086]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of autophagy [GO:0010506]; regulation of exocytosis [GO:0017157]; regulation of ion transmembrane transport [GO:0034765]; release of sequestered calcium ion into cytosol [GO:0051209]; response to vitamin D [GO:0033280]; smooth muscle contraction [GO:0006939]; sodium ion transmembrane transport [GO:0035725] GO:0005245; GO:0005262; GO:0005764; GO:0005765; GO:0005829; GO:0006874; GO:0006939; GO:0007040; GO:0010008; GO:0010506; GO:0015280; GO:0017157; GO:0019065; GO:0019722; GO:0019901; GO:0031902; GO:0033162; GO:0033280; GO:0034765; GO:0035725; GO:0036020; GO:0042802; GO:0048086; GO:0051209; GO:0051452; GO:0072345; GO:0075509; GO:0080025; GO:0090117; GO:0097682 41771 XM_044328196.1 434 214 275 1217 939 Q3ZMH1 6.24e-84 Sodium-coupled monocarboxylate transporter 1 (Electrogenic sodium monocarboxylate cotransporter) (zSMCTe) (Sodium solute symporter family 5 member 8 protein) (Solute carrier family 5 member 8) Danio rerio (Zebrafish) (Brachydanio rerio) sodium ion transport [GO:0006814] GO:0006814; GO:0015293; GO:0015355; GO:0016020 41772 XM_029332768.2 2104 1247 1048 1888 1600 G5EBQ8 2.99e-107 Chitin synthase chs-2 (EC 2.4.1.16) (Chitin-UDP acetyl-glucosaminyl transferase chs-2) Caenorhabditis elegans cell wall chitin biosynthetic process [GO:0006038]; chitin biosynthetic process [GO:0006031]; positive regulation of nematode larval development [GO:0061063] GO:0004100; GO:0005886; GO:0006031; GO:0006038; GO:0030428; GO:0061063; GO:0071944 41773 XM_044313352.1 1 1 0 0 7 NA NA NA NA NA NA 41774 XM_029335954.2 5 14 27 13 26 Q29S14 2.74e-72 Golgi apparatus membrane protein TVP23 homolog B Bos taurus (Bovine) protein secretion [GO:0009306]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0009306; GO:0016192 41775 XM_029339494.2 1185 928 740 987 872 Q5I0S8 1e-81 Leukocyte elastase inhibitor (Serpin B1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) negative regulation of peptidase activity [GO:0010466] GO:0004867; GO:0005615; GO:0005737; GO:0010466 41776 XM_044312115.1 21 46 6 33 46 NA NA NA NA NA NA 41777 XM_044319609.1 7 7 35 0 60 P30974 2.91e-33 Tachykinin-like peptides receptor 86C (NKD) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; inter-male aggressive behavior [GO:0002121]; neuropeptide signaling pathway [GO:0007218]; tachykinin receptor signaling pathway [GO:0007217] GO:0002121; GO:0004995; GO:0005886; GO:0007186; GO:0007217; GO:0007218; GO:0008188; GO:0016020 41778 XM_044323281.1 288 137 70 102 136 Q08CY9 1.63e-157 EGF domain-specific O-linked N-acetylglucosamine transferase (EC 2.4.1.255) (Extracellular O-linked N-acetylglucosamine transferase) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) protein O-linked glycosylation [GO:0006493] GO:0005788; GO:0006493; GO:0097363 41779 XM_044325334.1 5 7 2 23 9 A6QLU6 5.55e-51 Adhesion G-protein coupled receptor D1 (G-protein coupled receptor 133) Bos taurus (Bovine) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0005886; GO:0007166; GO:0007186; GO:0007189 41780 XM_029324087.2 1886 1677 1150 1204 970 Q8R4E0 5.3e-40 Interferon regulatory factor 2 (IRF-2) Sigmodon hispidus (Hispid cotton rat) NA GO:0000976; GO:0003700; GO:0005634 41781 XM_044327075.1 326 0 421 144 849 Q9BXW9 0 Fanconi anemia group D2 protein (Protein FACD2) Homo sapiens (Human) brain morphogenesis [GO:0048854]; cellular response to oxidative stress [GO:0034599]; double-strand break repair involved in meiotic recombination [GO:1990918]; gamete generation [GO:0007276]; homologous chromosome pairing at meiosis [GO:0007129]; interstrand cross-link repair [GO:0036297]; mitotic intra-S DNA damage checkpoint signaling [GO:0031573]; neuronal stem cell population maintenance [GO:0097150]; regulation of CD40 signaling pathway [GO:2000348]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of inflammatory response [GO:0050727]; regulation of regulatory T cell differentiation [GO:0045589]; response to gamma radiation [GO:0010332] GO:0000785; GO:0000793; GO:0005634; GO:0005654; GO:0005730; GO:0005829; GO:0007129; GO:0007276; GO:0010332; GO:0016604; GO:0031573; GO:0034599; GO:0036297; GO:0045589; GO:0048854; GO:0050727; GO:0051090; GO:0070182; GO:0097150; GO:1990391; GO:1990918; GO:2000348 41782 XM_029331774.2 5304 7903 3630 6542 5332 NA NA NA NA NA NA 41783 XM_029335162.2 5 23 1 14 23 NA NA NA NA NA NA 41784 XM_044313230.1 1082 531 509 1000 1100 Q91147 5.15e-76 Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) Notophthalmus viridescens (Eastern newt) (Triturus viridescens) apoptotic process [GO:0006915]; positive regulation of cell population proliferation [GO:0008284] GO:0005007; GO:0005524; GO:0005794; GO:0005886; GO:0006915; GO:0008284; GO:0031410 41785 XM_029340767.2 13 0 0 2 8 A0JN69 3e-38 E3 ubiquitin-protein ligase MARCHF3 (EC 2.3.2.27) (Membrane-associated RING finger protein 3) (Membrane-associated RING-CH protein III) (MARCH-III) (RING-type E3 ubiquitin transferase MARCHF3) Bos taurus (Bovine) endocytosis [GO:0006897]; protein ubiquitination [GO:0016567] GO:0004842; GO:0005764; GO:0005768; GO:0006897; GO:0008270; GO:0016567; GO:0031901 41786 XM_029335301.2 397 220 198 168 383 Q6ZMY6 2.15e-89 WD repeat-containing protein 88 (PQQ repeat and WD repeat-containing protein) Homo sapiens (Human) NA NA 41787 XR_006394624.1 111 34 10 74 88 Q9Z0R0 1.93e-83 Serine/threonine-protein kinase haspin (EC 2.7.11.1) (Germ cell-specific gene 2 protein) (Haploid germ cell-specific nuclear protein kinase) Mus musculus (Mouse) chromatin organization [GO:0006325]; chromosome organization involved in meiotic cell cycle [GO:0070192]; gene expression [GO:0010467]; homologous chromosome segregation [GO:0045143]; intracellular signal transduction [GO:0035556]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; mitotic spindle assembly checkpoint signaling [GO:0007094]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; protein localization to chromosome, centromeric region [GO:0071459]; protein phosphorylation [GO:0006468] GO:0000278; GO:0001673; GO:0003677; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005694; GO:0005737; GO:0005813; GO:0005819; GO:0006325; GO:0006468; GO:0007064; GO:0007094; GO:0010467; GO:0035173; GO:0035556; GO:0045143; GO:0070192; GO:0071459; GO:0072354; GO:0106310; GO:2000134 41788 XM_044312099.1 43 9 47 31 50 NA NA NA NA NA NA 41789 XM_044327233.1 7 14 14 0 22 Q96RW7 4.97e-25 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 41790 XM_044323748.1 0 0 8 0 0 NA NA NA NA NA NA 41791 XM_029345389.2 291 29 46 271 362 P28562 5.17e-83 Dual specificity protein phosphatase 1 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity protein phosphatase hVH1) (Mitogen-activated protein kinase phosphatase 1) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase CL100) Homo sapiens (Human) cell cycle [GO:0007049]; cellular response to chemokine [GO:1990869]; endoderm formation [GO:0001706]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of meiotic cell cycle [GO:0051447]; negative regulation of monocyte chemotaxis [GO:0090027]; negative regulation of p38MAPK cascade [GO:1903753]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; peptidyl-tyrosine dephosphorylation [GO:0035335]; regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090266] GO:0001706; GO:0004721; GO:0004722; GO:0004725; GO:0005634; GO:0005737; GO:0007049; GO:0007162; GO:0008138; GO:0008285; GO:0008330; GO:0017017; GO:0017018; GO:0035335; GO:0035970; GO:0043407; GO:0043409; GO:0051019; GO:0051447; GO:0070262; GO:0090027; GO:0090266; GO:1903753; GO:1990869 41792 XR_006395216.1 51 8 18 4 113 NA NA NA NA NA NA 41793 XM_044319389.1 6 0 0 0 0 Q9CUX1 8.07e-52 52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (THAP domain-containing protein 0) (THAP domain-containing protein 12) Mus musculus (Mouse) NA GO:0003677; GO:0005634; GO:0046872; GO:0046983 41794 XM_029356158.2 640 111 89 564 371 Q9EPE9 0 Endoplasmic reticulum transmembrane helix translocase (EC 7.4.2.-) (Endoplasmic reticulum P5A-ATPase) Mus musculus (Mouse) cellular calcium ion homeostasis [GO:0006874]; extraction of mislocalized protein from ER membrane [GO:0140569]; protein transport [GO:0015031]; transmembrane transport [GO:0055085] GO:0005524; GO:0005789; GO:0006874; GO:0015031; GO:0015662; GO:0016020; GO:0016887; GO:0019829; GO:0046872; GO:0055085; GO:0140567; GO:0140569 41795 XM_029333635.2 56 95 138 90 121 Q2KJG1 2.35e-26 Spermatogenesis-associated protein 6 Bos taurus (Bovine) cell differentiation [GO:0030154]; motile cilium assembly [GO:0044458]; spermatogenesis [GO:0007283] GO:0005576; GO:0007283; GO:0030154; GO:0032027; GO:0044458; GO:0097224 41796 XM_029351517.2 124 62 0 0 0 Q05BQ1 2.72e-48 Protein turtle homolog A (Dendrite arborization and synapse maturation protein 1) (Immunoglobulin superfamily member 9A) (IgSF9A) Mus musculus (Mouse) cell-cell adhesion [GO:0098609]; dendrite development [GO:0016358]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; regulation of synapse organization [GO:0050807] GO:0005886; GO:0007156; GO:0016358; GO:0030424; GO:0030425; GO:0050807; GO:0060077; GO:0098609; GO:0098632 41797 XM_029341500.2 0 7 109 0 128 NA NA NA NA NA NA 41798 XM_029357284.2 2954 3383 1049 3438 1208 A5PJX7 1.2e-108 Sodium- and chloride-dependent GABA transporter 2 (GAT-2) (Solute carrier family 6 member 13) Bos taurus (Bovine) amino acid import across plasma membrane [GO:0089718]; neurotransmitter transport [GO:0006836]; positive regulation of necrotic cell death [GO:0010940]; sodium ion transmembrane transport [GO:0035725] GO:0005332; GO:0005886; GO:0006836; GO:0010940; GO:0016323; GO:0035725; GO:0043005; GO:0089718 41799 XR_006391571.1 82 224 71 45 109 NA NA NA NA NA NA 41800 XM_044324211.1 12 1 0 0 0 G8XYX6 2.09e-53 Monocarboxylate transporter 8 (MCT 8) (Solute carrier family 16 member 2) Danio rerio (Zebrafish) (Brachydanio rerio) brain development [GO:0007420]; central nervous system development [GO:0007417]; chordate embryonic development [GO:0043009]; locomotion [GO:0040011]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; Schwann cell differentiation [GO:0014037]; spinal cord development [GO:0021510]; spinal cord oligodendrocyte cell differentiation [GO:0021529]; thyroid gland development [GO:0030878] GO:0007417; GO:0007420; GO:0014037; GO:0015349; GO:0016324; GO:0021510; GO:0021529; GO:0030182; GO:0030878; GO:0040011; GO:0043009; GO:0048709; GO:0070324 41801 XR_003823724.2 27 0 48 13 46 NA NA NA NA NA NA 41802 XM_044320728.1 121 161 114 194 116 NA NA NA NA NA NA 41803 XM_029341120.2 232 354 88 213 431 Q9NS91 2.99e-39 E3 ubiquitin-protein ligase RAD18 (EC 2.3.2.27) (Postreplication repair protein RAD18) (hHR18) (hRAD18) (RING finger protein 73) (RING-type E3 ubiquitin transferase RAD18) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; negative regulation of cell death [GO:0060548]; positive regulation of chromosome segregation [GO:0051984]; postreplication repair [GO:0006301]; protein autoubiquitination [GO:0051865]; protein monoubiquitination [GO:0006513] GO:0000403; GO:0003684; GO:0003697; GO:0005634; GO:0005654; GO:0005657; GO:0005737; GO:0005813; GO:0006281; GO:0006301; GO:0006513; GO:0006974; GO:0016604; GO:0031593; GO:0031625; GO:0035861; GO:0042405; GO:0042802; GO:0044877; GO:0046872; GO:0051865; GO:0051984; GO:0060548; GO:0061630; GO:0097505; GO:0140678 41804 XR_006394480.1 1 16 15 12 1 NA NA NA NA NA NA 41805 XM_044323760.1 20 0 11 1 8 NA NA NA NA NA NA 41806 XM_029332256.2 0 3 3 0 13 NA NA NA NA NA NA 41807 XM_029334909.2 938 1666 1955 5 453 NA NA NA NA NA NA 41808 XM_029333380.2 55 7 36 62 80 Q80W94 2.06e-71 2-acylglycerol O-acyltransferase 2 (EC 2.3.1.22) (Acyl-CoA:monoacylglycerol acyltransferase 2) (MGAT2) (Diacylglycerol acyltransferase 2-like protein 5) (Monoacylglycerol O-acyltransferase 1-like) (Monoacylglycerol O-acyltransferase 2) Mus musculus (Mouse) diacylglycerol biosynthetic process [GO:0006651]; glycerol metabolic process [GO:0006071]; intestinal absorption [GO:0050892]; lipid metabolic process [GO:0006629]; monoacylglycerol biosynthetic process [GO:0006640]; monoacylglycerol metabolic process [GO:0046462]; triglyceride biosynthetic process [GO:0019432] GO:0003846; GO:0005783; GO:0005789; GO:0006071; GO:0006629; GO:0006640; GO:0006651; GO:0008374; GO:0016407; GO:0019432; GO:0046462; GO:0050892; GO:1990578 41809 XM_044310155.1 9 4 16 12 7 NA NA NA NA NA NA 41810 XM_029324302.2 138 221 87 132 113 Q3EC11 4.23e-70 Probable protein S-acyltransferase 23 (EC 2.3.1.225) (Probable palmitoyltransferase At2g14255) (Zinc finger DHHC domain-containing protein At2g14255) Arabidopsis thaliana (Mouse-ear cress) peptidyl-L-cysteine S-palmitoylation [GO:0018230]; protein targeting to membrane [GO:0006612] GO:0000139; GO:0005783; GO:0005794; GO:0006612; GO:0018230; GO:0019706 41811 XM_044308428.1 852 719 516 1084 1603 A5PJG7 9.75e-78 Holocytochrome c-type synthase (EC 4.4.1.17) (Cytochrome c-type heme lyase) (CCHL) Bos taurus (Bovine) cytochrome c-heme linkage [GO:0018063] GO:0004408; GO:0005739; GO:0005743; GO:0018063; GO:0020037; GO:0046872 41812 XM_029340589.2 1202 1189 982 1289 790 Q9DCR2 2.32e-103 AP-3 complex subunit sigma-1 (AP-3 complex subunit sigma-3A) (Adaptor-related protein complex 3 subunit sigma-1) (Sigma-3A-adaptin) (Sigma3A-adaptin) (Sigma-adaptin 3a) Mus musculus (Mouse) anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; clathrin-coated vesicle cargo loading, AP-3-mediated [GO:0035654]; Golgi to vacuole transport [GO:0006896]; intracellular protein transport [GO:0006886]; intracellular transport [GO:0046907]; melanosome assembly [GO:1903232]; platelet dense granule organization [GO:0060155]; synaptic vesicle coating [GO:0016183]; synaptic vesicle recycling [GO:0036465]; vesicle-mediated transport [GO:0016192] GO:0005769; GO:0005802; GO:0006886; GO:0006896; GO:0008089; GO:0016020; GO:0016183; GO:0016192; GO:0030123; GO:0030659; GO:0035654; GO:0036465; GO:0043231; GO:0046907; GO:0048490; GO:0060155; GO:0098793; GO:1903232; GO:1904115 41813 XM_029343838.2 0 0 0 150 133 Q9P2C4 4.67e-143 Transmembrane protein 181 Homo sapiens (Human) NA GO:0015643; GO:0016020 41814 XM_044325206.1 0 0 0 0 25 NA NA NA NA NA NA 41815 XM_044317800.1 227 84 90 103 37 A0A0H2VDN9 1.19e-24 Secretory immunoglobulin A-binding protein EsiB Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) negative regulation of immune response [GO:0050777]; negative regulation of neutrophil activation [GO:1902564] GO:0009986; GO:0019862; GO:0046872; GO:0050777; GO:1902564 41816 XM_044317800.1 227 84 90 103 37 A0A0H2VDN9 1.69e-24 Secretory immunoglobulin A-binding protein EsiB Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) negative regulation of immune response [GO:0050777]; negative regulation of neutrophil activation [GO:1902564] GO:0009986; GO:0019862; GO:0046872; GO:0050777; GO:1902564 41817 XM_044317800.1 227 84 90 103 37 A0A0H2VDN9 5.93e-21 Secretory immunoglobulin A-binding protein EsiB Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) negative regulation of immune response [GO:0050777]; negative regulation of neutrophil activation [GO:1902564] GO:0009986; GO:0019862; GO:0046872; GO:0050777; GO:1902564 41818 XM_029338643.2 50 63 0 38 35 P00767 2.87e-36 Chymotrypsinogen B (EC 3.4.21.1) [Cleaved into: Chymotrypsin B chain A; Chymotrypsin B chain B; Chymotrypsin B chain C] Bos taurus (Bovine) digestion [GO:0007586]; proteolysis [GO:0006508] GO:0004252; GO:0005615; GO:0006508; GO:0007586 41819 XM_029330329.2 0 78 0 0 1 O43933 2.87e-171 Peroxisomal ATPase PEX1 (EC 3.6.4.-) (Peroxin-1) (Peroxisome biogenesis disorder protein 1) (Peroxisome biogenesis factor 1) Homo sapiens (Human) microtubule-based peroxisome localization [GO:0060152]; peroxisome organization [GO:0007031]; protein import into peroxisome matrix [GO:0016558]; protein import into peroxisome matrix, receptor recycling [GO:0016562]; protein targeting to peroxisome [GO:0006625]; protein unfolding [GO:0043335] GO:0005524; GO:0005737; GO:0005777; GO:0005778; GO:0005829; GO:0006625; GO:0007031; GO:0008022; GO:0016558; GO:0016562; GO:0016887; GO:0043335; GO:0044877; GO:0060152; GO:0070062; GO:0140036; GO:0140318 41820 XM_044314689.1 3436 4095 2332 1258 1599 I6LDA6 0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (iPGM) (EC 5.4.2.12) (Cofactor-independent phosphoglycerate mutase homolog) Onchocerca volvulus glucose catabolic process [GO:0006007]; glycolytic process [GO:0006096] GO:0004619; GO:0005737; GO:0006007; GO:0006096; GO:0030145 41821 XM_044324871.1 127 71 52 57 62 P07099 1.43e-121 Epoxide hydrolase 1 (EC 3.3.2.9) (Epoxide hydratase) (Microsomal epoxide hydrolase) (mEH) Homo sapiens (Human) arachidonic acid metabolic process [GO:0019369]; aromatic compound catabolic process [GO:0019439]; epoxide metabolic process [GO:0097176]; response to organic cyclic compound [GO:0014070]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805] GO:0004301; GO:0005789; GO:0006805; GO:0009636; GO:0014070; GO:0019369; GO:0019439; GO:0033961; GO:0097176 41822 XM_044323554.1 8 0 12 0 75 NA NA NA NA NA NA 41823 XM_029343760.2 1105 579 455 743 603 A1L224 5.37e-45 Cyclic AMP-responsive element-binding protein 3-like protein 2 (cAMP-responsive element-binding protein 3-like protein 2) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3-like protein 2] Danio rerio (Zebrafish) (Brachydanio rerio) cartilage development [GO:0051216]; chondrocyte differentiation [GO:0002062]; regulation of ER to Golgi vesicle-mediated transport [GO:0060628]; regulation of extracellular matrix constituent secretion [GO:0003330]; regulation of transcription by RNA polymerase II [GO:0006357]; response to endoplasmic reticulum stress [GO:0034976]; response to unfolded protein [GO:0006986] GO:0000976; GO:0000981; GO:0002062; GO:0003330; GO:0005634; GO:0005783; GO:0005789; GO:0006357; GO:0006986; GO:0034976; GO:0035497; GO:0051216; GO:0060628 41824 XM_044310232.1 23 1 40 7 47 NA NA NA NA NA NA 41825 XM_029337213.2 1171 865 301 1007 379 NA NA NA NA NA NA 41826 XM_044307086.1 129 165 135 121 263 NA NA NA NA NA NA 41827 XM_029335500.2 1644 1370 305 857 1289 Q32M45 1.84e-84 Anoctamin-4 (Transmembrane protein 16D) Homo sapiens (Human) calcium activated galactosylceramide scrambling [GO:0061591]; calcium activated phosphatidylcholine scrambling [GO:0061590]; calcium activated phosphatidylserine scrambling [GO:0061589]; chloride transmembrane transport [GO:1902476]; chloride transport [GO:0006821]; establishment of localization in cell [GO:0051649]; ion transmembrane transport [GO:0034220]; transmembrane transport [GO:0055085] GO:0005229; GO:0005254; GO:0005886; GO:0006821; GO:0017128; GO:0034220; GO:0046983; GO:0051649; GO:0055085; GO:0061589; GO:0061590; GO:0061591; GO:1902476 41828 XM_044307331.1 10 6 13 5 10 NA NA NA NA NA NA 41829 XM_044326636.1 93 90 47 80 94 NA NA NA NA NA NA 41830 XM_044326798.1 51 25 32 14 69 NA NA NA NA NA NA 41831 XR_006398109.1 52 355 46 103 27 NA NA NA NA NA NA 41832 XR_006392227.1 3 9 0 0 0 NA NA NA NA NA NA 41833 XM_029346954.2 128 54 109 130 157 F8VPZ5 1.74e-178 DNA excision repair protein ERCC-6 (EC 3.6.4.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB) Mus musculus (Mouse) base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; chromatin remodeling [GO:0006338]; DNA damage checkpoint signaling [GO:0000077]; DNA protection [GO:0042262]; DNA repair [GO:0006281]; double-strand break repair via classical nonhomologous end joining [GO:0097680]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; multicellular organism growth [GO:0035264]; negative regulation of double-strand break repair via nonhomologous end joining [GO:2001033]; neurogenesis [GO:0022008]; neuron differentiation [GO:0030182]; neuron projection development [GO:0031175]; photoreceptor cell maintenance [GO:0045494]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of gene expression [GO:0010628]; positive regulation of histone acetylation [GO:0035066]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription by RNA polymerase III [GO:0045945]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; pyrimidine dimer repair [GO:0006290]; regulation of DNA-templated transcription elongation [GO:0032784]; regulation of transcription elongation by RNA polymerase II [GO:0034243]; response to gamma radiation [GO:0010332]; response to oxidative stress [GO:0006979]; response to superoxide [GO:0000303]; response to toxic substance [GO:0009636]; response to UV [GO:0009411]; response to UV-B [GO:0010224]; response to X-ray [GO:0010165]; single strand break repair [GO:0000012]; transcription elongation by RNA polymerase I [GO:0006362]; transcription-coupled nucleotide-excision repair [GO:0006283] GO:0000012; GO:0000077; GO:0000303; GO:0002230; GO:0003677; GO:0003682; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0006281; GO:0006283; GO:0006284; GO:0006290; GO:0006338; GO:0006362; GO:0006974; GO:0006979; GO:0007254; GO:0008022; GO:0008023; GO:0008094; GO:0008630; GO:0009411; GO:0009636; GO:0010165; GO:0010224; GO:0010332; GO:0010628; GO:0016604; GO:0016887; GO:0022008; GO:0030182; GO:0030296; GO:0031175; GO:0032784; GO:0032786; GO:0033141; GO:0034243; GO:0035066; GO:0035264; GO:0042262; GO:0043565; GO:0044877; GO:0045494; GO:0045739; GO:0045943; GO:0045944; GO:0045945; GO:0047485; GO:0060261; GO:0070063; GO:0090734; GO:0097680; GO:0110016; GO:0140658; GO:1905168; GO:2001033 41834 XR_003823773.2 187 91 47 155 191 NA NA NA NA NA NA 41835 XM_029348963.2 1027 624 852 1193 1564 NA NA NA NA NA NA 41836 XM_029331529.2 160 150 84 185 183 Q58D06 3.44e-83 WD repeat-containing protein 74 Bos taurus (Bovine) blastocyst formation [GO:0001825]; ribosomal large subunit biogenesis [GO:0042273]; RNA metabolic process [GO:0016070]; rRNA processing [GO:0006364] GO:0000176; GO:0001825; GO:0005634; GO:0005654; GO:0005730; GO:0006364; GO:0016070; GO:0030687; GO:0042273 41837 XM_029345430.2 31 18 40 117 34 NA NA NA NA NA NA 41838 XM_029357290.2 819 548 550 984 986 G5EBX9 0 Serine/threonine-protein phosphatase with EF-hands pef-1 (CePPEF) (EC 3.1.3.16) (Phosphatase with EF hands 1) Caenorhabditis elegans detection of stimulus involved in sensory perception [GO:0050906] GO:0004722; GO:0005506; GO:0005509; GO:0005634; GO:0005829; GO:0005886; GO:0005929; GO:0017018; GO:0030145; GO:0030424; GO:0030425; GO:0043025; GO:0043204; GO:0050906 41839 XM_044317470.1 422 312 92 352 440 NA NA NA NA NA NA 41840 XM_029335601.2 518 0 59 0 1763 O70521 2.53e-37 Regulator of G-protein signaling 19 (RGS19) (G-alpha-interacting protein) (GAIP) Rattus norvegicus (Rat) negative regulation of signal transduction [GO:0009968]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; response to ethanol [GO:0045471] GO:0000139; GO:0001965; GO:0005096; GO:0005737; GO:0005903; GO:0008277; GO:0009968; GO:0016020; GO:0030136; GO:0045121; GO:0045471 41841 XM_029325440.2 23 61 65 45 55 A6H584 1.42e-25 Collagen alpha-5(VI) chain (Collagen alpha-1(XXIX) chain) Mus musculus (Mouse) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005576; GO:0005581; GO:0007155; GO:0030198; GO:0031012; GO:0062023 41842 XR_003826420.2 0 0 0 12 0 NA NA NA NA NA NA 41843 XM_029351642.2 4279 1299 2812 832 588 Q6DGQ0 1.41e-40 Transcription elongation factor SPT4 (DRB sensitivity-inducing factor small subunit) (DSIF small subunit) Danio rerio (Zebrafish) (Brachydanio rerio) chromatin organization [GO:0006325]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; regulation of transcription elongation by RNA polymerase II [GO:0034243] GO:0000993; GO:0006325; GO:0008270; GO:0032044; GO:0032786; GO:0034243 41844 XR_006392302.1 2090 3410 796 1473 822 NA NA NA NA NA NA 41845 XM_029351614.2 4767 5331 2564 3847 2674 NA NA NA NA NA NA 41846 XM_044324473.1 24 26 34 7 12 NA NA NA NA NA NA 41847 XM_029340033.2 1497 1659 2913 2749 2084 NA NA NA NA NA NA 41848 XM_029351362.2 2101 2004 1074 1671 1403 Q19749 9.67e-164 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial (EC 2.3.1.12) (Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex) (Pyruvate dehydrogenase complex component E2) (PDC-E2) (PDCE2) Caenorhabditis elegans acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glycolytic process [GO:0006096] GO:0004742; GO:0005967; GO:0006086; GO:0006096 41849 XR_006397234.1 0 17 0 0 0 NA NA NA NA NA NA 41850 XR_006393526.1 0 6 0 5 21 NA NA NA NA NA NA 41851 XM_044311423.1 1 1 0 13 15 NA NA NA NA NA NA 41852 XM_044316998.1 0 0 3 14 52 NA NA NA NA NA NA 41853 XR_006391846.1 0 0 0 0 119 NA NA NA NA NA NA 41854 XM_044317642.1 5220 3116 2836 5372 5340 Q6ZRS2 0 Helicase SRCAP (EC 3.6.4.-) (Domino homolog 2) (Snf2-related CBP activator) Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000786; GO:0000812; GO:0003677; GO:0003713; GO:0004386; GO:0004402; GO:0005524; GO:0005634; GO:0005654; GO:0005794; GO:0006355; GO:0006357; GO:0016604; GO:0016887; GO:0032991; GO:0042393; GO:0048471; GO:0140658 41855 XM_044317642.1 5220 3116 2836 5372 5340 Q6ZRS2 8.45e-118 Helicase SRCAP (EC 3.6.4.-) (Domino homolog 2) (Snf2-related CBP activator) Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000786; GO:0000812; GO:0003677; GO:0003713; GO:0004386; GO:0004402; GO:0005524; GO:0005634; GO:0005654; GO:0005794; GO:0006355; GO:0006357; GO:0016604; GO:0016887; GO:0032991; GO:0042393; GO:0048471; GO:0140658 41856 XM_044317642.1 5220 3116 2836 5372 5340 Q6ZRS2 9.11e-47 Helicase SRCAP (EC 3.6.4.-) (Domino homolog 2) (Snf2-related CBP activator) Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000786; GO:0000812; GO:0003677; GO:0003713; GO:0004386; GO:0004402; GO:0005524; GO:0005634; GO:0005654; GO:0005794; GO:0006355; GO:0006357; GO:0016604; GO:0016887; GO:0032991; GO:0042393; GO:0048471; GO:0140658 41857 XM_044314578.1 47 0 13 0 0 Q5M7N9 3.43e-76 Extended synaptotagmin-3 (E-Syt3) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) endoplasmic reticulum-plasma membrane tethering [GO:0061817]; lipid transport [GO:0006869] GO:0005789; GO:0005886; GO:0006869; GO:0008289; GO:0046872; GO:0061817; GO:0140268 41858 XM_029344436.2 2082 2023 1280 1696 1219 Q5R687 1.25e-54 Insulin-induced gene 2 protein (INSIG-2) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cholesterol biosynthetic process [GO:0006695]; cranial suture morphogenesis [GO:0060363]; inner ear morphogenesis [GO:0042472]; middle ear morphogenesis [GO:0042474]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of steroid biosynthetic process [GO:0010894]; roof of mouth development [GO:0060021]; SREBP signaling pathway [GO:0032933]; SREBP-SCAP complex retention in endoplasmic reticulum [GO:0036316]; triglyceride metabolic process [GO:0006641] GO:0006641; GO:0006695; GO:0008142; GO:0010894; GO:0032933; GO:0032937; GO:0036316; GO:0042472; GO:0042474; GO:0045717; GO:0060021; GO:0060363 41859 XM_044326778.1 0 0 2 4 30 NA NA NA NA NA NA 41860 XM_044310119.1 12 107 0 0 164 NA NA NA NA NA NA 41861 XM_044321832.1 272 0 205 77 157 Q9D6D8 7.88e-66 Probable inactive peptidyl-prolyl cis-trans isomerase-like 6 (PPIase) (Cyclophilin-like protein PPIL6) Mus musculus (Mouse) protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413] GO:0000413; GO:0003755; GO:0005737; GO:0006457 41862 XM_044321303.1 327 466 466 545 226 NA NA NA NA NA NA 41863 XR_006394240.1 0 7 0 0 0 NA NA NA NA NA NA 41864 XR_006394003.1 11 39 111 17 11 NA NA NA NA NA NA 41865 XM_044325342.1 1060 720 711 623 710 NA NA NA NA NA NA 41866 XM_044327027.1 64 72 62 59 17 NA NA NA NA NA NA 41867 XR_003823854.2 79 22 136 135 205 NA NA NA NA NA NA 41868 XM_044310302.1 0 6 0 34 18 NA NA NA NA NA NA 41869 XM_029328780.2 0 28 0 91 0 Q2XWK0 2.56e-156 Synaptic vesicle 2-related protein (SV2-related protein) Xenopus laevis (African clawed frog) NA GO:0022857; GO:0030672 41870 XM_044318457.1 0 0 0 0 8 NA NA NA NA NA NA 41871 XR_006397785.1 1176 311 138 229 199 NA NA NA NA NA NA 41872 XM_044313602.1 24 278 0 341 588 Q7ZXY0 0 Inositol-3-phosphate synthase 1-A (IPS 1-A) (EC 5.5.1.4) (Myo-inositol 1-phosphate synthase A) (MI-1-P synthase A) (MIP synthase A) Xenopus laevis (African clawed frog) inositol biosynthetic process [GO:0006021]; phospholipid biosynthetic process [GO:0008654] GO:0004512; GO:0005737; GO:0006021; GO:0008654 41873 XM_044308855.1 11 3 0 0 36 P35546 3.55e-63 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; anatomical structure morphogenesis [GO:0009653]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006919; GO:0007156; GO:0007158; GO:0007169; GO:0007399; GO:0009410; GO:0009653; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030182; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0098797; GO:2001241 41874 XM_029355276.2 43 24 15 49 51 Q9EQC4 1.56e-65 Elongation of very long chain fatty acids protein 4 (EC 2.3.1.199) (3-keto acyl-CoA synthase Elovl4) (ELOVL fatty acid elongase 4) (ELOVL FA elongase 4) (Very long chain 3-ketoacyl-CoA synthase 4) (Very long chain 3-oxoacyl-CoA synthase 4) Mus musculus (Mouse) fatty acid elongation, monounsaturated fatty acid [GO:0034625]; fatty acid elongation, polyunsaturated fatty acid [GO:0034626]; fatty acid elongation, saturated fatty acid [GO:0019367]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; sphingolipid biosynthetic process [GO:0030148]; unsaturated fatty acid biosynthetic process [GO:0006636]; very long-chain fatty acid biosynthetic process [GO:0042761] GO:0005783; GO:0005789; GO:0006636; GO:0009922; GO:0019367; GO:0030148; GO:0034625; GO:0034626; GO:0035338; GO:0042761; GO:0102756 41875 XR_006392319.1 12 18 11 30 10 NA NA NA NA NA NA 41876 XM_044315425.1 18 140 6 170 194 NA NA NA NA NA NA 41877 XM_044320666.1 23 148 33 124 134 Q7RTR2 2.65e-47 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 41878 XM_044320666.1 23 148 33 124 134 Q7RTR2 1.2e-45 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 41879 XM_044320666.1 23 148 33 124 134 Q7RTR2 6.08e-42 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 41880 XM_044320666.1 23 148 33 124 134 Q7RTR2 6.91e-38 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 41881 XM_044320666.1 23 148 33 124 134 Q7RTR2 1.94e-26 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 41882 XM_044320666.1 23 148 33 124 134 Q7RTR2 7.06e-25 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 41883 XM_044320666.1 23 148 33 124 134 Q7RTR2 1.34e-22 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 41884 XM_029345763.2 609 38 380 621 728 O43592 0 Exportin-T (Exportin(tRNA)) (tRNA exportin) Homo sapiens (Human) intracellular protein transport [GO:0006886]; tRNA export from nucleus [GO:0006409]; tRNA re-export from nucleus [GO:0071528] GO:0000049; GO:0005643; GO:0005654; GO:0005737; GO:0005829; GO:0006409; GO:0006886; GO:0016363; GO:0031267; GO:0071528 41885 XM_044323364.1 43 22 0 54 2 NA NA NA NA NA NA 41886 XM_044307441.1 0 0 2 1 12 Q61554 5.17e-49 Fibrillin-1 [Cleaved into: Asprosin] Mus musculus (Mouse) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; kidney development [GO:0001822]; metanephros development [GO:0001656]; negative regulation of brown fat cell differentiation [GO:1903444]; negative regulation of insulin secretion [GO:0046676]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0001822; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0046676; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1903444; GO:1990314; GO:2001205 41887 XM_044307441.1 0 0 2 1 12 Q61554 5.26e-39 Fibrillin-1 [Cleaved into: Asprosin] Mus musculus (Mouse) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; kidney development [GO:0001822]; metanephros development [GO:0001656]; negative regulation of brown fat cell differentiation [GO:1903444]; negative regulation of insulin secretion [GO:0046676]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0001822; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0046676; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1903444; GO:1990314; GO:2001205 41888 XM_044307441.1 0 0 2 1 12 Q61554 4.33e-37 Fibrillin-1 [Cleaved into: Asprosin] Mus musculus (Mouse) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; kidney development [GO:0001822]; metanephros development [GO:0001656]; negative regulation of brown fat cell differentiation [GO:1903444]; negative regulation of insulin secretion [GO:0046676]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0001822; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0046676; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1903444; GO:1990314; GO:2001205 41889 XM_044307441.1 0 0 2 1 12 Q61554 1.21e-34 Fibrillin-1 [Cleaved into: Asprosin] Mus musculus (Mouse) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; kidney development [GO:0001822]; metanephros development [GO:0001656]; negative regulation of brown fat cell differentiation [GO:1903444]; negative regulation of insulin secretion [GO:0046676]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0001822; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0046676; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1903444; GO:1990314; GO:2001205 41890 XM_044307441.1 0 0 2 1 12 Q61554 1.38e-31 Fibrillin-1 [Cleaved into: Asprosin] Mus musculus (Mouse) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; kidney development [GO:0001822]; metanephros development [GO:0001656]; negative regulation of brown fat cell differentiation [GO:1903444]; negative regulation of insulin secretion [GO:0046676]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0001822; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0046676; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1903444; GO:1990314; GO:2001205 41891 XM_044307441.1 0 0 2 1 12 Q61554 2.24e-31 Fibrillin-1 [Cleaved into: Asprosin] Mus musculus (Mouse) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; kidney development [GO:0001822]; metanephros development [GO:0001656]; negative regulation of brown fat cell differentiation [GO:1903444]; negative regulation of insulin secretion [GO:0046676]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0001822; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0046676; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1903444; GO:1990314; GO:2001205 41892 XM_044307441.1 0 0 2 1 12 Q61554 1.34e-30 Fibrillin-1 [Cleaved into: Asprosin] Mus musculus (Mouse) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; kidney development [GO:0001822]; metanephros development [GO:0001656]; negative regulation of brown fat cell differentiation [GO:1903444]; negative regulation of insulin secretion [GO:0046676]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0001822; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0046676; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1903444; GO:1990314; GO:2001205 41893 XM_044307441.1 0 0 2 1 12 Q61554 1.76e-30 Fibrillin-1 [Cleaved into: Asprosin] Mus musculus (Mouse) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; kidney development [GO:0001822]; metanephros development [GO:0001656]; negative regulation of brown fat cell differentiation [GO:1903444]; negative regulation of insulin secretion [GO:0046676]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0001822; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0046676; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1903444; GO:1990314; GO:2001205 41894 XM_044307441.1 0 0 2 1 12 Q61554 5.72e-27 Fibrillin-1 [Cleaved into: Asprosin] Mus musculus (Mouse) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; kidney development [GO:0001822]; metanephros development [GO:0001656]; negative regulation of brown fat cell differentiation [GO:1903444]; negative regulation of insulin secretion [GO:0046676]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0001822; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0046676; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1903444; GO:1990314; GO:2001205 41895 XM_044307441.1 0 0 2 1 12 Q61554 1.17e-26 Fibrillin-1 [Cleaved into: Asprosin] Mus musculus (Mouse) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; kidney development [GO:0001822]; metanephros development [GO:0001656]; negative regulation of brown fat cell differentiation [GO:1903444]; negative regulation of insulin secretion [GO:0046676]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0001822; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0046676; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1903444; GO:1990314; GO:2001205 41896 XM_044307441.1 0 0 2 1 12 Q61554 1.66e-26 Fibrillin-1 [Cleaved into: Asprosin] Mus musculus (Mouse) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; kidney development [GO:0001822]; metanephros development [GO:0001656]; negative regulation of brown fat cell differentiation [GO:1903444]; negative regulation of insulin secretion [GO:0046676]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0001822; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0046676; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1903444; GO:1990314; GO:2001205 41897 XM_044307441.1 0 0 2 1 12 Q61554 1.76e-24 Fibrillin-1 [Cleaved into: Asprosin] Mus musculus (Mouse) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; kidney development [GO:0001822]; metanephros development [GO:0001656]; negative regulation of brown fat cell differentiation [GO:1903444]; negative regulation of insulin secretion [GO:0046676]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0001822; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0046676; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1903444; GO:1990314; GO:2001205 41898 XM_044307441.1 0 0 2 1 12 Q61554 2.35e-24 Fibrillin-1 [Cleaved into: Asprosin] Mus musculus (Mouse) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; kidney development [GO:0001822]; metanephros development [GO:0001656]; negative regulation of brown fat cell differentiation [GO:1903444]; negative regulation of insulin secretion [GO:0046676]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0001822; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0046676; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1903444; GO:1990314; GO:2001205 41899 XM_044307441.1 0 0 2 1 12 Q61554 2.47e-23 Fibrillin-1 [Cleaved into: Asprosin] Mus musculus (Mouse) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; kidney development [GO:0001822]; metanephros development [GO:0001656]; negative regulation of brown fat cell differentiation [GO:1903444]; negative regulation of insulin secretion [GO:0046676]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0001822; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0046676; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1903444; GO:1990314; GO:2001205 41900 XM_044307441.1 0 0 2 1 12 Q61554 4.42e-22 Fibrillin-1 [Cleaved into: Asprosin] Mus musculus (Mouse) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; kidney development [GO:0001822]; metanephros development [GO:0001656]; negative regulation of brown fat cell differentiation [GO:1903444]; negative regulation of insulin secretion [GO:0046676]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0001822; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0046676; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1903444; GO:1990314; GO:2001205 41901 XR_006391879.1 121 81 31 360 279 NA NA NA NA NA NA 41902 XR_006394742.1 60 176 102 183 251 NA NA NA NA NA NA 41903 XM_029332787.2 54 81 28 11 42 Q8VDR5 5.26e-32 Transmembrane protein 267 Mus musculus (Mouse) NA GO:0016020 41904 XM_044328805.1 0 0 0 0 10 NA NA NA NA NA NA 41905 XM_044318133.1 0 16 0 0 3 NA NA NA NA NA NA 41906 XR_006397482.1 21 16 44 38 73 NA NA NA NA NA NA 41907 XM_029348166.2 130 171 102 25 137 Q6NW96 1.77e-80 Transcription factor Sp9 Danio rerio (Zebrafish) (Brachydanio rerio) embryonic limb morphogenesis [GO:0030326]; embryonic pectoral fin morphogenesis [GO:0035118]; positive regulation of fibroblast growth factor receptor signaling pathway [GO:0045743]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0030326; GO:0035118; GO:0045743; GO:0046872 41908 XM_029351075.2 853 562 462 573 711 Q9NW82 0 WD repeat-containing protein 70 Homo sapiens (Human) NA GO:0005634; GO:0019899; GO:0035861 41909 XM_044311404.1 42 63 59 60 54 NA NA NA NA NA NA 41910 XM_044310400.1 1919 0 1148 0 853 NA NA NA NA NA NA 41911 XM_044310725.1 15 0 11 17 58 NA NA NA NA NA NA 41912 XM_029330154.2 43 11 0 39 0 NA NA NA NA NA NA 41913 XM_044316598.1 59 0 5 0 22 NA NA NA NA NA NA 41914 XM_044328597.1 1494 1065 978 1455 1456 A7SLW1 0 Branched-chain-amino-acid aminotransferase (EC 2.6.1.42) Nematostella vectensis (Starlet sea anemone) leucine biosynthetic process [GO:0009098]; valine biosynthetic process [GO:0009099] GO:0004084; GO:0005739; GO:0009098; GO:0009099; GO:0050048; GO:0052654; GO:0052655; GO:0052656 41915 XR_006394656.1 4 0 11 0 77 NA NA NA NA NA NA 41916 XM_029323854.2 0 0 0 0 275 Q566X8 1.03e-33 Diencephalon/mesencephalon homeobox protein 1-B Danio rerio (Zebrafish) (Brachydanio rerio) midbrain development [GO:0030901]; regulation of cell cycle [GO:0051726]; regulation of mitotic cell cycle [GO:0007346]; regulation of neural retina development [GO:0061074]; regulation of neurogenesis [GO:0050767]; regulation of transcription by RNA polymerase II [GO:0006357]; retina development in camera-type eye [GO:0060041] GO:0000977; GO:0000981; GO:0005634; GO:0006357; GO:0007346; GO:0030901; GO:0050767; GO:0051726; GO:0060041; GO:0061074 41917 XM_029358052.2 2035 1920 1174 1936 2656 NA NA NA NA NA NA 41918 XM_029334055.2 671 278 312 372 755 Q9UKY4 0 Protein O-mannosyl-transferase 2 (EC 2.4.1.109) (Dolichyl-phosphate-mannose--protein mannosyltransferase 2) Homo sapiens (Human) positive regulation of protein O-linked glycosylation [GO:1904100]; protein O-linked mannosylation [GO:0035269] GO:0000030; GO:0004169; GO:0005654; GO:0005730; GO:0005783; GO:0005789; GO:0005829; GO:0035269; GO:0046872; GO:1904100 41919 XM_029356112.2 0 0 27 0 0 Q98982 6.57e-27 Substance-P receptor (SPR) (NK-1 receptor) (NK-1R) (Tachykinin receptor 1) Lithobates catesbeianus (American bullfrog) (Rana catesbeiana) NA GO:0004995; GO:0005886 41920 XM_029356396.2 108 67 16 0 0 Q6ZR37 4.1e-84 Pleckstrin homology domain-containing family G member 7 (PH domain-containing family G member 7) Homo sapiens (Human) Rho protein signal transduction [GO:0007266] GO:0005085; GO:0007266 41921 XR_006392764.1 10 14 12 0 14 NA NA NA NA NA NA 41922 XM_029330375.2 6 0 0 0 0 P45953 0 Very long-chain specific acyl-CoA dehydrogenase, mitochondrial (VLCAD) (EC 1.3.8.9) Rattus norvegicus (Rat) epithelial cell differentiation [GO:0030855]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; fatty acid catabolic process [GO:0009062]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of fatty acid oxidation [GO:0046322]; regulation of cholesterol metabolic process [GO:0090181]; response to cold [GO:0009409]; temperature homeostasis [GO:0001659] GO:0000062; GO:0001659; GO:0003995; GO:0004466; GO:0005739; GO:0005743; GO:0006635; GO:0009062; GO:0009409; GO:0017099; GO:0030855; GO:0031314; GO:0031966; GO:0033539; GO:0042645; GO:0042802; GO:0045717; GO:0046322; GO:0050660; GO:0090181 41923 XM_029334679.2 725 834 952 978 703 Q4R747 3.67e-23 Leucine-rich repeat-containing protein 46 Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA NA 41924 XR_006396349.1 13 29 23 66 17 NA NA NA NA NA NA 41925 XM_029332055.2 350 344 219 417 488 NA NA NA NA NA NA 41926 XM_044312953.1 166 57 31 9 119 Q8K3Z0 4.02e-31 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 41927 XM_029348698.2 0 0 0 20 69 Q9D787 0 RING-type E3 ubiquitin-protein ligase PPIL2 (EC 2.3.2.27) (CYC4) (Probable inactive peptidyl-prolyl cis-trans isomerase-like 2) (PPIase) Mus musculus (Mouse) protein folding [GO:0006457]; protein localization to plasma membrane [GO:0072659]; protein peptidyl-prolyl isomerization [GO:0000413]; protein polyubiquitination [GO:0000209] GO:0000209; GO:0000413; GO:0003755; GO:0004842; GO:0005634; GO:0005654; GO:0005737; GO:0005886; GO:0006457; GO:0034450; GO:0061630; GO:0071013; GO:0072659 41928 XM_029355562.2 165 103 318 188 781 NA NA NA NA NA NA 41929 XM_029328919.2 195 135 127 191 151 Q9H553 2.57e-152 Alpha-1,3/1,6-mannosyltransferase ALG2 (EC 2.4.1.132) (EC 2.4.1.257) (Asparagine-linked glycosylation protein 2 homolog) (GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase) (GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase) (GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase) Homo sapiens (Human) dolichol-linked oligosaccharide biosynthetic process [GO:0006488]; oligosaccharide-lipid intermediate biosynthetic process [GO:0006490]; protein glycosylation [GO:0006486]; response to calcium ion [GO:0051592] GO:0000033; GO:0004378; GO:0005634; GO:0005737; GO:0005789; GO:0006486; GO:0006488; GO:0006490; GO:0016020; GO:0046982; GO:0047485; GO:0048306; GO:0048471; GO:0051592; GO:0102704 41930 XM_029355280.2 487 537 276 646 1167 NA NA NA NA NA NA 41931 XM_044313345.1 37 2 58 4 12 NA NA NA NA NA NA 41932 XM_044320544.1 0 0 0 0 14 NA NA NA NA NA NA 41933 XM_029329520.2 331 251 215 331 262 Q9CX47 7.87e-63 DNA repair protein XRCC2 (X-ray repair cross-complementing protein 2) Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; centrosome cycle [GO:0007098]; DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; in utero embryonic development [GO:0001701]; mitotic cell cycle [GO:0000278]; multicellular organism growth [GO:0035264]; negative regulation of neuron apoptotic process [GO:0043524]; neurogenesis [GO:0022008]; positive regulation of neurogenesis [GO:0050769]; regulation of fibroblast apoptotic process [GO:2000269]; response to gamma radiation [GO:0010332]; response to X-ray [GO:0010165]; somitogenesis [GO:0001756]; strand invasion [GO:0042148] GO:0000278; GO:0000400; GO:0000724; GO:0001701; GO:0001756; GO:0005524; GO:0005654; GO:0005657; GO:0005813; GO:0006281; GO:0006974; GO:0007098; GO:0010165; GO:0010332; GO:0022008; GO:0033063; GO:0035264; GO:0042148; GO:0043231; GO:0043524; GO:0050769; GO:0140664; GO:2000269 41934 XM_029339943.2 624 404 321 374 259 A4YI89 2.96e-36 3-hydroxypropionyl-coenzyme A dehydratase (3-hydroxypropionyl-CoA dehydratase) (EC 4.2.1.116) Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2) fatty acid metabolic process [GO:0006631] GO:0006631; GO:0043956 41935 XM_029327243.2 60 106 37 13 0 NA NA NA NA NA NA 41936 XR_006398165.1 11 7 8 24 9 NA NA NA NA NA NA 41937 XM_029333804.2 131 104 92 172 187 NA NA NA NA NA NA 41938 XM_029338517.2 8802 7540 4111 5829 5232 P27465 5.89e-112 Phosphatidylserine decarboxylase proenzyme, mitochondrial (EC 4.1.1.65) [Cleaved into: Phosphatidylserine decarboxylase beta chain; Phosphatidylserine decarboxylase alpha chain] Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) lipid droplet formation [GO:0140042]; mitochondrial protein catabolic process [GO:0035694]; phosphatidylethanolamine biosynthetic process [GO:0006646]; protein autoprocessing [GO:0016540]; regulation of mitochondrion organization [GO:0010821] GO:0004609; GO:0005634; GO:0005739; GO:0005743; GO:0005811; GO:0006646; GO:0010821; GO:0016540; GO:0035694; GO:0140042 41939 XM_029337844.2 687 382 930 985 502 Q8BH58 3.14e-82 TIP41-like protein Mus musculus (Mouse) DNA damage checkpoint signaling [GO:0000077]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; regulation of phosphoprotein phosphatase activity [GO:0043666]; TOR signaling [GO:0031929] GO:0000077; GO:0005829; GO:0031929; GO:0032515; GO:0043666 41940 XR_003823051.2 2 3 3 7 12 NA NA NA NA NA NA 41941 XM_044322187.1 0 9 35 20 65 NA NA NA NA NA NA 41942 XM_029328874.2 0 59 65 264 357 Q28DB0 7.01e-160 Tetratricopeptide repeat protein 39B (TPR repeat protein 39B) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) lipid metabolic process [GO:0006629] GO:0006629 41943 XR_006396173.1 147 48 16 88 20 NA NA NA NA NA NA 41944 XM_029336143.2 4 6 4 2 92 NA NA NA NA NA NA 41945 XM_029346732.2 303 53 104 31 224 NA NA NA NA NA NA 41946 XM_029346942.2 2621 4078 1570 3278 2778 NA NA NA NA NA NA 41947 XM_029347996.2 263 0 139 318 67 NA NA NA NA NA NA 41948 XM_029340382.2 0 0 0 15 14 Q9R1C8 4.91e-23 5-hydroxytryptamine receptor 6 (5-HT-6) (5-HT6) (Serotonin receptor 6) Mus musculus (Mouse) cerebral cortex cell migration [GO:0021795]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; learning [GO:0007612]; long-term synaptic potentiation [GO:0060291]; negative regulation of acetylcholine secretion, neurotransmission [GO:0014058]; negative regulation of gamma-aminobutyric acid secretion [GO:0014053]; negative regulation of glutamate secretion [GO:0014050]; positive regulation of dopamine secretion [GO:0033603]; positive regulation of gamma-aminobutyric acid secretion [GO:0014054]; positive regulation of TOR signaling [GO:0032008] GO:0004993; GO:0005886; GO:0005929; GO:0007187; GO:0007268; GO:0007612; GO:0014050; GO:0014053; GO:0014054; GO:0014058; GO:0021795; GO:0030425; GO:0030594; GO:0032008; GO:0033603; GO:0045202; GO:0060291 41949 XM_044317538.1 30 11 46 34 13 Q8IN35 2.12e-36 Neuropeptide SIFamide receptor Drosophila melanogaster (Fruit fly) determination of adult lifespan [GO:0008340]; G protein-coupled receptor signaling pathway [GO:0007186]; mating behavior, sex discrimination [GO:0048047]; neuropeptide signaling pathway [GO:0007218] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0008340; GO:0008528; GO:0016020; GO:0042277; GO:0048047 41950 XM_029345041.2 1 374 97 0 0 NA NA NA NA NA NA 41951 XM_044319966.1 2231 1733 1160 1775 2307 NA NA NA NA NA NA 41952 XM_029336201.2 23822 18630 16951 29445 37001 Q9PWF7 0 Catalase (EC 1.11.1.6) Glandirana rugosa (Japanese wrinkled frog) (Rana rugosa) hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979] GO:0004096; GO:0005777; GO:0006979; GO:0020037; GO:0042744; GO:0046872 41953 XR_006396193.1 408 207 135 183 551 A3KN83 0 Protein strawberry notch homolog 1 (Monocyte protein 3) (MOP-3) Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355]; regulation of response to stimulus [GO:0048583] GO:0005634; GO:0006355; GO:0031490; GO:0042393; GO:0048583 41954 XR_006396193.1 408 207 135 183 551 A3KN83 3.79e-33 Protein strawberry notch homolog 1 (Monocyte protein 3) (MOP-3) Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355]; regulation of response to stimulus [GO:0048583] GO:0005634; GO:0006355; GO:0031490; GO:0042393; GO:0048583 41955 XM_044319244.1 0 31 0 137 92 Q3T052 1.23e-105 Inter-alpha-trypsin inhibitor heavy chain H4 (ITI heavy chain H4) (ITI-HC4) (Inter-alpha-inhibitor heavy chain 4) Bos taurus (Bovine) acute-phase response [GO:0006953]; hyaluronan metabolic process [GO:0030212]; negative regulation of peptidase activity [GO:0010466] GO:0004867; GO:0005576; GO:0006953; GO:0010466; GO:0030212 41956 XM_044312411.1 598 261 84 222 94 Q9NZM1 0 Myoferlin (Fer-1-like protein 3) Homo sapiens (Human) blood circulation [GO:0008015]; membrane fusion [GO:0061025]; muscle contraction [GO:0006936]; plasma membrane organization [GO:0007009]; plasma membrane repair [GO:0001778]; T-tubule organization [GO:0033292] GO:0001778; GO:0005543; GO:0005635; GO:0005886; GO:0005901; GO:0006936; GO:0007009; GO:0008015; GO:0030659; GO:0031410; GO:0031965; GO:0033292; GO:0043231; GO:0046872; GO:0061025; GO:0070062 41957 XM_029352508.2 31 123 19 88 202 NA NA NA NA NA NA 41958 XM_029356531.2 0 10 0 0 12 Q9WUP7 3.24e-149 Ubiquitin carboxyl-terminal hydrolase isozyme L5 (UCH-L5) (EC 3.4.19.12) (Ubiquitin C-terminal hydrolase UCH37) (Ubiquitin thioesterase L5) Mus musculus (Mouse) chromatin remodeling [GO:0006338]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; forebrain morphogenesis [GO:0048853]; lateral ventricle development [GO:0021670]; midbrain development [GO:0030901]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of telomere maintenance in response to DNA damage [GO:1904507]; protein deubiquitination [GO:0016579]; regulation of cell cycle [GO:0051726]; regulation of chromosome organization [GO:0033044]; regulation of DNA repair [GO:0006282]; regulation of DNA replication [GO:0006275]; regulation of DNA strand elongation [GO:0060382]; regulation of embryonic development [GO:0045995]; regulation of proteasomal protein catabolic process [GO:0061136]; telomere maintenance [GO:0000723]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000723; GO:0004843; GO:0004866; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0006275; GO:0006281; GO:0006282; GO:0006310; GO:0006338; GO:0006511; GO:0016579; GO:0021670; GO:0030901; GO:0031011; GO:0031597; GO:0032435; GO:0033044; GO:0045739; GO:0045880; GO:0045893; GO:0045995; GO:0048853; GO:0051726; GO:0060382; GO:0061136; GO:0070628; GO:1904507 41959 XM_029341665.2 54 6 117 0 45 NA NA NA NA NA NA 41960 XM_029352489.2 27 0 37 0 53 Q6VVW5 1.29e-76 Atrial natriuretic peptide receptor 2 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type B) (ANP-B) (ANPR-B) (NPR-B) (Guanylate cyclase B) (GC-B) Mus musculus (Mouse) activation of meiosis involved in egg activation [GO:0060466]; axonogenesis [GO:0007409]; axonogenesis involved in innervation [GO:0060385]; blood circulation [GO:0008015]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; bone development [GO:0060348]; bone growth [GO:0098868]; c-di-GMP signaling [GO:0061939]; cartilage development [GO:0051216]; cellular response to cGMP [GO:0071321]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to peptide [GO:1901653]; cGMP biosynthetic process [GO:0006182]; cGMP metabolic process [GO:0046068]; cGMP-mediated signaling [GO:0019934]; chemical synaptic transmission [GO:0007268]; chondrocyte differentiation [GO:0002062]; chondrocyte proliferation [GO:0035988]; chromosome organization [GO:0051276]; collateral sprouting [GO:0048668]; cumulus cell differentiation [GO:0001549]; digestive tract development [GO:0048565]; digestive tract morphogenesis [GO:0048546]; endochondral ossification [GO:0001958]; epidermal growth factor receptor signaling pathway [GO:0007173]; execution phase of apoptosis [GO:0097194]; female genitalia development [GO:0030540]; gastric emptying [GO:0035483]; genitalia morphogenesis [GO:0035112]; germ cell development [GO:0007281]; growth plate cartilage development [GO:0003417]; limb development [GO:0060173]; limb morphogenesis [GO:0035108]; lymph vessel development [GO:0001945]; MAPK cascade [GO:0000165]; meiotic cell cycle [GO:0051321]; meiotic cell cycle process involved in oocyte maturation [GO:1903537]; multicellular organism growth [GO:0035264]; multicellular organism reproduction [GO:0032504]; negative regulation of meiotic cell cycle [GO:0051447]; negative regulation of oocyte maturation [GO:1900194]; nerve development [GO:0021675]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; oocyte development [GO:0048599]; ovarian follicle development [GO:0001541]; positive regulation of cGMP-mediated signaling [GO:0010753]; post-anal tail morphogenesis [GO:0036342]; protein phosphorylation [GO:0006468]; receptor guanylyl cyclase signaling pathway [GO:0007168]; reproductive process [GO:0022414]; response to fibroblast growth factor [GO:0071774]; response to hormone [GO:0009725]; response to luteinizing hormone [GO:0034699]; response to salt [GO:1902074]; response to wounding [GO:0009611]; sensory perception of sound [GO:0007605]; signal transduction [GO:0007165]; single fertilization [GO:0007338]; smooth muscle tissue development [GO:0048745]; spermatogenesis [GO:0007283]; startle response [GO:0001964]; vacuole organization [GO:0007033]; vascular wound healing [GO:0061042]; vasculogenesis [GO:0001570]; vestibulocochlear nerve development [GO:0021562]; vestibulocochlear nerve maturation [GO:0021647]; white fat cell differentiation [GO:0050872] GO:0000165; GO:0001541; GO:0001549; GO:0001568; GO:0001570; GO:0001653; GO:0001945; GO:0001958; GO:0001964; GO:0001974; GO:0002062; GO:0003417; GO:0004383; GO:0004672; GO:0005524; GO:0005525; GO:0005634; GO:0005737; GO:0005886; GO:0005929; GO:0006182; GO:0006468; GO:0007033; GO:0007165; GO:0007168; GO:0007173; GO:0007268; GO:0007281; GO:0007283; GO:0007338; GO:0007409; GO:0007605; GO:0008015; GO:0009611; GO:0009725; GO:0010753; GO:0016941; GO:0017046; GO:0019228; GO:0019934; GO:0021562; GO:0021647; GO:0021675; GO:0022414; GO:0030540; GO:0032504; GO:0034699; GO:0035108; GO:0035112; GO:0035264; GO:0035483; GO:0035988; GO:0036342; GO:0042562; GO:0042802; GO:0043005; GO:0045202; GO:0046068; GO:0048546; GO:0048565; GO:0048599; GO:0048668; GO:0048745; GO:0050872; GO:0051216; GO:0051276; GO:0051321; GO:0051402; GO:0051447; GO:0060173; GO:0060348; GO:0060385; GO:0060466; GO:0061042; GO:0061939; GO:0071321; GO:0071774; GO:0097011; GO:0097194; GO:0098868; GO:1900194; GO:1901653; GO:1902074; GO:1903537 41961 XM_029339285.2 668 417 379 393 313 Q9H6D7 2.47e-33 HAUS augmin-like complex subunit 4 Homo sapiens (Human) cell division [GO:0051301]; centrosome cycle [GO:0007098]; spindle assembly [GO:0051225] GO:0005813; GO:0005829; GO:0007098; GO:0051011; GO:0051225; GO:0051301; GO:0070652; GO:1990498 41962 XR_006392355.1 3 14 18 7 6 NA NA NA NA NA NA 41963 XM_044323346.1 18 0 17 0 12 NA NA NA NA NA NA 41964 XM_044313529.1 58 74 13 45 12 Q5R4R7 1.58e-36 PHD finger protein 24 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0046872 41965 XM_044318886.1 10413 11388 8037 10547 14920 NA NA NA NA NA NA 41966 XM_044310616.1 0 0 0 0 53 NA NA NA NA NA NA 41967 XM_029347836.2 1630 1489 1036 2217 712 NA NA NA NA NA NA 41968 XM_044310693.1 83 0 0 98 7 A3KMX0 0 DNA excision repair protein ERCC-6-like 2 (EC 3.6.4.-) Bos taurus (Bovine) DNA repair [GO:0006281] GO:0003677; GO:0004386; GO:0005524; GO:0005634; GO:0005739; GO:0005815; GO:0006281; GO:0016787; GO:0140658 41969 XM_044310693.1 83 0 0 98 7 A3KMX0 1.53e-21 DNA excision repair protein ERCC-6-like 2 (EC 3.6.4.-) Bos taurus (Bovine) DNA repair [GO:0006281] GO:0003677; GO:0004386; GO:0005524; GO:0005634; GO:0005739; GO:0005815; GO:0006281; GO:0016787; GO:0140658 41970 XM_044311725.1 6 0 132 0 93 NA NA NA NA NA NA 41971 XM_029335110.2 1709 2206 1055 1442 1374 Q9QZS6 8.53e-92 Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (3-OST-3B) (Heparan sulfate 3-O-sulfotransferase 3B1) (m3-OST-3B) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; protein sulfation [GO:0006477] GO:0000139; GO:0001658; GO:0005886; GO:0006024; GO:0006477; GO:0008467; GO:0015012; GO:0033872 41972 XM_029335302.2 0 37 0 0 0 Q6ZMY6 1.37e-87 WD repeat-containing protein 88 (PQQ repeat and WD repeat-containing protein) Homo sapiens (Human) NA NA 41973 XM_029354244.2 4 0 1 3 28 NA NA NA NA NA NA 41974 XM_029349931.1 5 10 1 11 4 NA NA NA NA NA NA 41975 XM_044326573.1 133 70 54 84 488 Q96SK2 6.58e-88 Transmembrane protein 209 Homo sapiens (Human) NA GO:0016020 41976 XM_044316404.1 490 305 269 583 400 P11533 6.21e-60 Dystrophin Gallus gallus (Chicken) actin filament bundle assembly [GO:0051017]; actin filament network formation [GO:0051639] GO:0005737; GO:0005884; GO:0008270; GO:0032432; GO:0042383; GO:0045211; GO:0051015; GO:0051017; GO:0051639; GO:0120025 41977 XM_044315877.1 9 17 18 16 13 NA NA NA NA NA NA 41978 XM_029323707.2 48 10 0 8 36 Q68ED7 5.21e-23 CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1 homolog) (Transducer of regulated cAMP response element-binding protein 1) (TORC-1) (Transducer of CREB protein 1) Mus musculus (Mouse) energy homeostasis [GO:0097009]; entrainment of circadian clock by photoperiod [GO:0043153]; memory [GO:0007613]; negative regulation of membrane hyperpolarization [GO:1902631]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of dendrite development [GO:1900006]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of transcription by RNA polymerase II [GO:0045944]; postsynapse to nucleus signaling pathway [GO:0099527]; protein homotetramerization [GO:0051289]; rhythmic process [GO:0048511] GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0007613; GO:0008140; GO:0014069; GO:0016604; GO:0030425; GO:0032793; GO:0043025; GO:0043153; GO:0045202; GO:0045944; GO:0048511; GO:0051289; GO:0097009; GO:0098978; GO:0099527; GO:1900006; GO:1900273; GO:1902631 41979 XR_006391434.1 15 1 22 40 23 NA NA NA NA NA NA 41980 XM_044320042.1 334 188 161 255 187 Q15760 1.94e-32 Probable G-protein coupled receptor 19 (GPR-NGA) Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0005886; GO:0005929; GO:0007186 41981 XM_044328864.1 0 1 6 0 0 NA NA NA NA NA NA 41982 XM_044314408.1 52 0 0 96 0 Q2TBP0 1.28e-60 Proteasome subunit beta type-7 (EC 3.4.25.1) Bos taurus (Bovine) proteolysis involved in protein catabolic process [GO:0051603] GO:0004298; GO:0005634; GO:0005737; GO:0005839; GO:0019774; GO:0051603 41983 XM_029347929.2 170 31 25 169 187 Q2QRV3 3.59e-108 Alpha-dioxygenase PIOX (EC 1.13.11.92) (Pathogen-induced oxygenase) Oryza sativa subsp. japonica (Rice) (R)-2-hydroxy-alpha-linolenic acid biosynthetic process [GO:1902609]; cell death [GO:0008219]; cellular response to nitric oxide [GO:0071732]; cellular response to reactive oxygen species [GO:0034614]; cellular response to salicylic acid stimulus [GO:0071446]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; fatty acid alpha-oxidation [GO:0001561]; oxylipin biosynthetic process [GO:0031408]; response to abscisic acid [GO:0009737]; systemic acquired resistance [GO:0009627] GO:0001561; GO:0004601; GO:0008219; GO:0009627; GO:0009737; GO:0012511; GO:0016702; GO:0020037; GO:0031408; GO:0034614; GO:0042742; GO:0046872; GO:0050832; GO:0071446; GO:0071732; GO:1902609 41984 XM_029332537.2 367 237 252 521 559 Q8CDF7 4.19e-44 piRNA biogenesis protein EXD1 (Exonuclease 3'-5' domain-containing protein 1) (Exonuclease 3'-5' domain-like-containing protein 1) (Inactive exonuclease EXD1) (mExd1) Mus musculus (Mouse) meiotic cell cycle [GO:0051321]; piRNA processing [GO:0034587]; RNA-mediated gene silencing [GO:0031047] GO:0003723; GO:0031047; GO:0034587; GO:0042803; GO:0043186; GO:0051321; GO:1990923 41985 XM_029338882.2 0 49 0 119 0 NA NA NA NA NA NA 41986 XR_006395771.1 123 93 199 55 264 NA NA NA NA NA NA 41987 XR_006391684.1 317 68 67 191 101 NA NA NA NA NA NA 41988 XM_029338358.2 179 77 0 109 159 Q96F81 0 Protein dispatched homolog 1 Homo sapiens (Human) determination of left/right symmetry [GO:0007368]; diaphragm development [GO:0060539]; dorsal/ventral pattern formation [GO:0009953]; embryonic pattern specification [GO:0009880]; patched ligand maturation [GO:0007225]; peptide transport [GO:0015833]; protein homotrimerization [GO:0070207]; regulation of protein secretion [GO:0050708]; smoothened signaling pathway [GO:0007224]; transmembrane transport [GO:0055085] GO:0007224; GO:0007225; GO:0007368; GO:0009880; GO:0009953; GO:0015833; GO:0016020; GO:0016323; GO:0022857; GO:0050708; GO:0055085; GO:0060539; GO:0070207; GO:1904680 41989 XM_029337384.2 7489 5347 4506 6646 6445 Q61532 1.07e-89 Mitogen-activated protein kinase 6 (MAP kinase 6) (MAPK 6) (EC 2.7.11.24) (Extracellular signal-regulated kinase 3) (ERK-3) Mus musculus (Mouse) cell cycle [GO:0007049]; intracellular signal transduction [GO:0035556]; positive regulation of dendritic spine development [GO:0060999]; protein phosphorylation [GO:0006468] GO:0004672; GO:0004674; GO:0004707; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006468; GO:0007049; GO:0019901; GO:0032156; GO:0032991; GO:0035556; GO:0046982; GO:0060999; GO:0106310 41990 XM_044321344.1 150 94 121 164 67 Q13416 4.27e-106 Origin recognition complex subunit 2 Homo sapiens (Human) DNA replication initiation [GO:0006270]; negative regulation of transcription by RNA polymerase II [GO:0000122] GO:0000122; GO:0000781; GO:0000792; GO:0000808; GO:0000939; GO:0003688; GO:0005634; GO:0005654; GO:0005664; GO:0005813; GO:0006270; GO:0016020 41991 XM_029337366.2 425 300 175 187 319 Q5T7B8 2.85e-125 Kinesin-like protein KIF24 Homo sapiens (Human) cilium assembly [GO:0060271]; microtubule depolymerization [GO:0007019]; microtubule-based movement [GO:0007018]; negative regulation of cilium assembly [GO:1902018] GO:0003777; GO:0005524; GO:0005813; GO:0005814; GO:0005829; GO:0005874; GO:0007018; GO:0007019; GO:0008017; GO:0032991; GO:0042802; GO:0060271; GO:1902018 41992 XM_029339751.2 0 0 9 0 0 Q60564 8.67e-47 LIM homeobox transcription factor 1-beta (LIM/homeobox protein 1.2) (LMX-1.2) (LIM/homeobox protein LMX1B) Mesocricetus auratus (Golden hamster) system development [GO:0048731] GO:0000981; GO:0003677; GO:0005634; GO:0046872; GO:0048731 41993 XM_044318360.1 6 3 3 9 10 NA NA NA NA NA NA 41994 XR_006397962.1 7 0 7 25 20 NA NA NA NA NA NA 41995 XR_006396469.1 11 70 19 0 0 NA NA NA NA NA NA 41996 XM_029346018.2 605 236 242 468 369 P11362 4.01e-75 Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331) Homo sapiens (Human) cell migration [GO:0016477]; chordate embryonic development [GO:0043009]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; MAPK cascade [GO:0000165]; neuron migration [GO:0001764]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell differentiation [GO:0045595]; regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001239]; skeletal system development [GO:0001501]; skeletal system morphogenesis [GO:0048705]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0000165; GO:0001501; GO:0001764; GO:0001837; GO:0004713; GO:0004714; GO:0005007; GO:0005524; GO:0005576; GO:0005634; GO:0005829; GO:0005886; GO:0006468; GO:0007169; GO:0008201; GO:0008284; GO:0008543; GO:0010518; GO:0010863; GO:0014068; GO:0016020; GO:0016477; GO:0017134; GO:0018108; GO:0031410; GO:0033674; GO:0042802; GO:0042803; GO:0043009; GO:0043235; GO:0043406; GO:0043410; GO:0043536; GO:0045595; GO:0045597; GO:0045666; GO:0046777; GO:0048015; GO:0048705; GO:0051897; GO:0090722; GO:1905564; GO:2000546; GO:2001239 41997 XM_029329814.2 595 469 391 556 792 Q6ZUK4 2.31e-21 Transmembrane protein 26 Homo sapiens (Human) NA GO:0016020 41998 XM_044323373.1 150 107 87 147 275 NA NA NA NA NA NA 41999 XM_044328235.1 21 0 0 15 8 P84239 6.64e-95 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 42000 XM_044317861.1 3 16 2 0 0 NA NA NA NA NA NA 42001 XM_044318438.1 7 7 0 0 6 Q94K49 1.73e-25 Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1 (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) epigenetic regulation of gene expression [GO:0040029] GO:0003682; GO:0004518; GO:0005634; GO:0035098; GO:0035102; GO:0040029; GO:0046872 42002 XM_044323406.1 43 18 43 75 109 NA NA NA NA NA NA 42003 XM_044311621.1 7 0 3 25 18 NA NA NA NA NA NA 42004 XM_044318427.1 0 2 0 0 18 NA NA NA NA NA NA 42005 XR_006391486.1 6 2 28 8 114 NA NA NA NA NA NA 42006 XM_044320923.1 1 0 6 3 4 NA NA NA NA NA NA 42007 XM_044313047.1 9 11 0 14 12 Q96AY4 2.24e-77 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 42008 XM_044313047.1 9 11 0 14 12 Q96AY4 5.62e-77 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 42009 XM_044313047.1 9 11 0 14 12 Q96AY4 7.56e-71 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 42010 XM_044313047.1 9 11 0 14 12 Q96AY4 6.4e-70 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 42011 XM_044313047.1 9 11 0 14 12 Q96AY4 4.36e-67 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 42012 XM_044313047.1 9 11 0 14 12 Q96AY4 1.02e-60 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 42013 XM_029323434.2 1428 958 844 1615 1425 Q6VY07 1.04e-140 Phosphofurin acidic cluster sorting protein 1 (PACS-1) Homo sapiens (Human) protein localization to Golgi apparatus [GO:0034067]; protein localization to plasma membrane [GO:0072659] GO:0005794; GO:0005829; GO:0030137; GO:0034067; GO:0044325; GO:0072659 42014 XM_044324177.1 665 411 103 535 675 P51655 6.67e-85 Glypican-4 (K-glypican) [Cleaved into: Secreted glypican-4] Mus musculus (Mouse) cell migration [GO:0016477]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of presynapse assembly [GO:1905606]; regulation of protein localization to membrane [GO:1905475]; regulation of signal transduction [GO:0009966]; synaptic membrane adhesion [GO:0099560]; Wnt signaling pathway [GO:0016055] GO:0005615; GO:0005796; GO:0009897; GO:0009966; GO:0009986; GO:0016055; GO:0016477; GO:0042734; GO:0045202; GO:0062023; GO:0098696; GO:0098978; GO:0099560; GO:1905475; GO:1905606 42015 XM_044318148.1 0 18 21 11 0 Q09470 9.62e-122 Potassium voltage-gated channel subfamily A member 1 (Voltage-gated K(+) channel HuKI) (Voltage-gated potassium channel HBK1) (Voltage-gated potassium channel subunit Kv1.1) Homo sapiens (Human) axon development [GO:0061564]; cell communication by electrical coupling [GO:0010644]; cellular response to magnesium ion [GO:0071286]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; corpus callosum development [GO:0022038]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; detection of mechanical stimulus involved in sensory perception of touch [GO:0050976]; hippocampus development [GO:0021766]; magnesium ion homeostasis [GO:0010960]; neuroblast proliferation [GO:0007405]; neuromuscular process [GO:0050905]; neuronal action potential [GO:0019228]; neuronal signal transduction [GO:0023041]; optic nerve development [GO:0021554]; positive regulation of voltage-gated potassium channel activity [GO:1903818]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; protein localization [GO:0008104]; regulation of membrane potential [GO:0042391]; regulation of muscle contraction [GO:0006937]; startle response [GO:0001964] GO:0001964; GO:0005249; GO:0005251; GO:0005267; GO:0005783; GO:0005829; GO:0005886; GO:0006813; GO:0006937; GO:0007268; GO:0007405; GO:0008076; GO:0008104; GO:0009986; GO:0010644; GO:0010960; GO:0015079; GO:0016020; GO:0016324; GO:0019228; GO:0021554; GO:0021766; GO:0021987; GO:0022038; GO:0023041; GO:0030054; GO:0030425; GO:0031410; GO:0033270; GO:0042391; GO:0042734; GO:0043025; GO:0043194; GO:0043204; GO:0043679; GO:0044224; GO:0044305; GO:0045202; GO:0045211; GO:0050905; GO:0050966; GO:0050976; GO:0051260; GO:0061564; GO:0070161; GO:0071286; GO:0071805; GO:0097718; GO:0098978; GO:0099508; GO:1903818; GO:1905030 42016 XM_029342852.2 40 27 46 84 38 NA NA NA NA NA NA 42017 XM_029334100.2 2835 2089 1398 2065 1739 Q9Y2H1 0 Serine/threonine-protein kinase 38-like (EC 2.7.11.1) (NDR2 protein kinase) (Nuclear Dbf2-related kinase 2) Homo sapiens (Human) intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; postsynapse organization [GO:0099173]; protein phosphorylation [GO:0006468]; regulation of cellular component organization [GO:0051128] GO:0000287; GO:0003779; GO:0004674; GO:0005524; GO:0005737; GO:0005829; GO:0006468; GO:0015629; GO:0016020; GO:0018105; GO:0035556; GO:0051128; GO:0098978; GO:0099173; GO:0106310 42018 XM_029344697.2 180 84 62 203 125 Q98925 7.44e-24 Interferon regulatory factor 2 (IRF-2) Gallus gallus (Chicken) immune system process [GO:0002376]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0002376; GO:0005634; GO:0006357 42019 XM_044325451.1 12 0 0 26 98 P19217 1.25e-56 Sulfotransferase 1E1 (ST1E1) (EC 2.8.2.4) (Estrogen sulfotransferase) (Sulfotransferase, estrogen-preferring) Bos taurus (Bovine) estrogen metabolic process [GO:0008210]; sulfation [GO:0051923] GO:0004062; GO:0004304; GO:0005496; GO:0005737; GO:0005829; GO:0008146; GO:0008210; GO:0050294; GO:0051923 42020 XM_044329296.1 2 2 0 0 21 NA NA NA NA NA NA 42021 XM_029337834.2 133 0 121 129 155 Q8BLA8 1.14e-115 Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Wasabi receptor) Mus musculus (Mouse) calcium ion transmembrane import into cytosol [GO:0097553]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cell surface receptor signaling pathway [GO:0007166]; cellular calcium ion homeostasis [GO:0006874]; cellular response to carbon dioxide [GO:0071244]; cellular response to cold [GO:0070417]; cellular response to heat [GO:0034605]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to organic substance [GO:0071310]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; positive regulation of anion transport [GO:1903793]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of sensory perception of pain [GO:1904058]; protein homotetramerization [GO:0051289]; regulation of blood circulation [GO:1903522]; regulation of neuronal action potential [GO:0098908]; response to cold [GO:0009409]; response to hydrogen peroxide [GO:0042542]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; sensory perception of pain [GO:0019233]; thermoception [GO:0050955]; urinary bladder smooth muscle contraction [GO:0014832] GO:0005216; GO:0005245; GO:0005262; GO:0005886; GO:0006816; GO:0006874; GO:0007166; GO:0009409; GO:0009410; GO:0010033; GO:0014070; GO:0014832; GO:0015267; GO:0015278; GO:0016020; GO:0016324; GO:0019233; GO:0030424; GO:0032421; GO:0034605; GO:0035774; GO:0042542; GO:0042802; GO:0048265; GO:0050955; GO:0050966; GO:0050968; GO:0050974; GO:0051289; GO:0070301; GO:0070417; GO:0070588; GO:0071244; GO:0071310; GO:0097553; GO:0097604; GO:0098908; GO:1903522; GO:1903793; GO:1904058; GO:1990760 42022 XR_003823456.2 13 5 7 1 56 NA NA NA NA NA NA 42023 XM_029326597.2 211 176 138 158 151 P42620 4.65e-122 Glutathionyl-hydroquinone reductase YqjG (GS-HQR) (EC 1.8.5.7) Escherichia coli (strain K12) NA GO:0004364; GO:0005737; GO:0016672 42024 XM_044314771.1 0 7 0 5 0 P20664 6.83e-158 DNA primase small subunit (EC 2.7.7.102) (DNA primase 49 kDa subunit) (p49) Mus musculus (Mouse) DNA replication initiation [GO:0006270]; DNA replication, synthesis of RNA primer [GO:0006269] GO:0000287; GO:0003896; GO:0005658; GO:0006269; GO:0006270; GO:0008270; GO:0032553 42025 XR_003824125.2 13 0 0 1 77 NA NA NA NA NA NA 42026 XM_044306804.1 30 55 77 205 218 O15033 6.73e-116 Apoptosis-resistant E3 ubiquitin protein ligase 1 (EC 2.3.2.26) (Apoptosis-resistant HECT-type E3 ubiquitin transferase 1) Homo sapiens (Human) apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K11-linked ubiquitination [GO:0070979]; protein K33-linked ubiquitination [GO:1990390]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of inflammatory response [GO:0050727]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000209; GO:0004842; GO:0005737; GO:0005829; GO:0006511; GO:0006915; GO:0016567; GO:0043066; GO:0043161; GO:0050727; GO:0061630; GO:0070979; GO:1990390 42027 XM_029334233.2 52 0 0 26 0 P25931 6.73e-34 RYamide receptor (Neuropeptide Y-like receptor) (NPY-R) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218] GO:0001653; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0016020 42028 XM_029333781.2 594 125 218 337 0 Q7TN88 2.78e-68 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 42029 XM_029333781.2 594 125 218 337 0 Q7TN88 2.78e-49 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 42030 XM_029328637.2 0 0 20 0 0 Q5ZKI0 9.9e-75 Calcium/calmodulin-dependent protein kinase type II delta chain (CaM kinase II subunit delta) (CaM-kinase II delta chain) (CaMK-II subunit delta) (EC 2.7.11.17) Gallus gallus (Chicken) protein phosphorylation [GO:0006468] GO:0004683; GO:0005516; GO:0005524; GO:0005737; GO:0006468; GO:0043005; GO:0106310 42031 XM_044307139.1 455 136 192 139 182 NA NA NA NA NA NA 42032 XM_029325266.2 1039 812 492 989 1155 F6QV99 2.38e-139 Outer mitochondrial transmembrane helix translocase (EC 7.4.2.-) (ATPase family AAA domain-containing protein 1) (Thorase) Bos taurus (Bovine) extraction of mislocalized protein from mitochondrial outer membrane [GO:0140570]; learning [GO:0007612]; memory [GO:0007613]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; positive regulation of receptor internalization [GO:0002092]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149] GO:0002092; GO:0005524; GO:0005741; GO:0005778; GO:0007612; GO:0007613; GO:0016887; GO:0045211; GO:0051967; GO:0098978; GO:0099149; GO:0140567; GO:0140570 42033 XM_029330600.2 17 5 7 13 1 NA NA NA NA NA NA 42034 XM_044313879.1 0 13 3 14 52 NA NA NA NA NA NA 42035 XM_029329792.2 0 31 3 0 0 Q6AYM1 1.31e-28 Uncharacterized protein C5orf34 homolog Rattus norvegicus (Rat) NA NA 42036 XM_044310514.1 0 0 0 7 0 Q91ZV3 1.64e-26 Discoidin, CUB and LCCL domain-containing protein 2 (Endothelial and smooth muscle cell-derived neuropilin-like protein) Mus musculus (Mouse) negative regulation of cell growth [GO:0030308]; wound healing [GO:0042060] GO:0005886; GO:0009986; GO:0030308; GO:0038023; GO:0042060 42037 XM_029325907.2 1506 1332 1144 1168 2898 Q8IVL5 1.53e-108 Prolyl 3-hydroxylase 2 (EC 1.14.11.7) (Leprecan-like protein 1) (Myxoid liposarcoma-associated protein 4) Homo sapiens (Human) collagen metabolic process [GO:0032963]; negative regulation of cell population proliferation [GO:0008285]; peptidyl-proline hydroxylation [GO:0019511] GO:0005506; GO:0005604; GO:0005654; GO:0005783; GO:0005788; GO:0005794; GO:0005829; GO:0008285; GO:0016529; GO:0019511; GO:0019797; GO:0031418; GO:0032963; GO:0043231 42038 XM_029351917.2 40 0 0 0 0 E9PZZ1 3.28e-37 PR domain zinc finger protein 13 (EC 2.1.1.-) (PR domain-containing protein 13) Mus musculus (Mouse) GABAergic neuron differentiation [GO:0097154]; hypothalamus cell differentiation [GO:0021979]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of gene expression [GO:0010468] GO:0000122; GO:0003677; GO:0003682; GO:0005634; GO:0010468; GO:0021979; GO:0022008; GO:0042054; GO:0046872; GO:0061629; GO:0097154 42039 XM_044321166.1 4411 4629 2188 5379 3726 P70195 6.96e-141 Proteasome subunit beta type-7 (EC 3.4.25.1) (Macropain chain Z) (Multicatalytic endopeptidase complex chain Z) (Proteasome subunit Z) Mus musculus (Mouse) proteasomal protein catabolic process [GO:0010498] GO:0000502; GO:0004175; GO:0004298; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005839; GO:0010498; GO:0016604; GO:0019774 42040 XR_006395080.1 59 15 20 16 70 NA NA NA NA NA NA 42041 XR_006392318.1 8 78 24 43 0 NA NA NA NA NA NA 42042 XM_044319999.1 104 0 71 0 0 P61765 0 Syntaxin-binding protein 1 (N-Sec1) (Protein unc-18 homolog 1) (Unc18-1) (Protein unc-18 homolog A) (Unc-18A) (p67) (rbSec1) Rattus norvegicus (Rat) axon target recognition [GO:0007412]; cellular response to type II interferon [GO:0071346]; developmental process involved in reproduction [GO:0003006]; establishment of localization in cell [GO:0051649]; exocytosis [GO:0006887]; intracellular protein transport [GO:0006886]; long-term synaptic depression [GO:0060292]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of SNARE complex assembly [GO:0035544]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; neuromuscular synaptic transmission [GO:0007274]; neuron apoptotic process [GO:0051402]; neurotransmitter secretion [GO:0007269]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of exocytosis [GO:0045921]; positive regulation of glutamate secretion, neurotransmission [GO:1903296]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of vesicle docking [GO:0106022]; presynaptic dense core vesicle exocytosis [GO:0099525]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; regulation of acrosomal vesicle exocytosis [GO:2000367]; regulation of synaptic vesicle priming [GO:0010807]; regulation of vesicle fusion [GO:0031338]; response to estradiol [GO:0032355]; SNARE complex assembly [GO:0035493]; synaptic vesicle maturation [GO:0016188]; synaptic vesicle priming [GO:0016082]; vesicle docking involved in exocytosis [GO:0006904]; vesicle-mediated transport [GO:0016192] GO:0000149; GO:0002576; GO:0003006; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0006886; GO:0006887; GO:0006904; GO:0007269; GO:0007274; GO:0007412; GO:0010807; GO:0016082; GO:0016188; GO:0016192; GO:0017075; GO:0019901; GO:0019904; GO:0019905; GO:0030141; GO:0030424; GO:0031091; GO:0031333; GO:0031338; GO:0032229; GO:0032355; GO:0032991; GO:0035493; GO:0035544; GO:0042802; GO:0043195; GO:0043274; GO:0043306; GO:0043524; GO:0045335; GO:0045921; GO:0045956; GO:0047485; GO:0048471; GO:0048787; GO:0050821; GO:0051402; GO:0051649; GO:0060090; GO:0060292; GO:0070527; GO:0071346; GO:0072659; GO:0098688; GO:0098793; GO:0098794; GO:0098831; GO:0098888; GO:0098978; GO:0099523; GO:0099525; GO:0106022; GO:1903296; GO:2000367 42043 XM_029329872.2 1945 1120 1130 2065 1851 Q9UBV2 0 Protein sel-1 homolog 1 (Suppressor of lin-12-like protein 1) (Sel-1L) Homo sapiens (Human) ERAD pathway [GO:0036503]; Notch signaling pathway [GO:0007219]; protein secretion [GO:0009306]; protein stabilization [GO:0050821]; retrograde protein transport, ER to cytosol [GO:0030970]; triglyceride metabolic process [GO:0006641]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0000836; GO:0000839; GO:0005783; GO:0005789; GO:0006641; GO:0007219; GO:0009306; GO:0030433; GO:0030970; GO:0036503; GO:0036513; GO:0050821 42044 XR_006393064.1 41 2 25 5 151 NA NA NA NA NA NA 42045 XM_029356302.2 77 73 46 104 165 Q95334 0 Glutamyl aminopeptidase (EAP) (EC 3.4.11.7) (Aminopeptidase A) (AP-A) (CD antigen CD249) Sus scrofa (Pig) cell migration [GO:0016477]; cell population proliferation [GO:0008283]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; signal transduction [GO:0007165] GO:0003081; GO:0004177; GO:0005737; GO:0005886; GO:0006508; GO:0007165; GO:0008217; GO:0008270; GO:0008283; GO:0016477; GO:0042277; GO:0043171; GO:0070006 42046 XM_044315265.1 3 0 16 0 0 NA NA NA NA NA NA 42047 XR_006395118.1 9 0 0 416 31 NA NA NA NA NA NA 42048 XM_044318907.1 375 485 62 283 187 Q60431 4.14e-68 Caspase-3 (CASP-3) (EC 3.4.22.56) (Apopain) (Cysteine protease CPP32) (CPP-32) (Protein Yama) (SREBP cleavage activity 1) (SCA-1) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12] Mesocricetus auratus (Golden hamster) intracellular signal transduction [GO:0035556]; positive regulation of amyloid-beta formation [GO:1902004]; proteolysis [GO:0006508]; regulation of protein stability [GO:0031647] GO:0004175; GO:0005737; GO:0006508; GO:0031647; GO:0035556; GO:0097153; GO:0097199; GO:0097200; GO:1902004 42049 XM_029336742.2 3702 2393 940 3624 2005 Q28DG7 1.6e-59 Ubiquitin-associated domain-containing protein 1 (UBA domain-containing protein 1) (E3 ubiquitin-protein ligase subunit KPC2) (Kip1 ubiquitination-promoting complex protein 2) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) protein ubiquitination [GO:0016567] GO:0005737; GO:0016567 42050 XM_029346392.2 5 0 0 6 3 NA NA NA NA NA NA 42051 XM_044309936.1 41 6 35 11 98 NA NA NA NA NA NA 42052 XR_003825367.2 19 14 2 7 5 NA NA NA NA NA NA 42053 XM_044323957.1 2 3 3 21 25 NA NA NA NA NA NA 42054 XR_006391979.1 679 533 196 608 762 NA NA NA NA NA NA 42055 XM_029333347.2 56 129 120 103 25 NA NA NA NA NA NA 42056 XM_044321831.1 209 284 17 380 155 Q9D6D8 2.11e-77 Probable inactive peptidyl-prolyl cis-trans isomerase-like 6 (PPIase) (Cyclophilin-like protein PPIL6) Mus musculus (Mouse) protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413] GO:0000413; GO:0003755; GO:0005737; GO:0006457 42057 XM_044327657.1 0 0 0 0 10 P24367 7.18e-59 Peptidyl-prolyl cis-trans isomerase B (PPIase B) (EC 5.2.1.8) (Cyclophilin B) (Rotamase B) (S-cyclophilin) (SCYLP) Gallus gallus (Chicken) chaperone-mediated protein folding [GO:0061077]; negative regulation of collagen fibril organization [GO:1904027]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413] GO:0000413; GO:0003755; GO:0005737; GO:0005788; GO:0006457; GO:0016018; GO:0032991; GO:0042470; GO:0043231; GO:0061077; GO:1904027 42058 XM_044312872.1 226 170 101 69 204 NA NA NA NA NA NA 42059 XM_029355655.2 12 9 8 19 15 NA NA NA NA NA NA 42060 XM_029338455.2 21 10 5 9 8 NA NA NA NA NA NA 42061 XM_044328165.1 34 22 14 17 45 NA NA NA NA NA NA 42062 XR_006395778.1 59 50 56 34 97 NA NA NA NA NA NA 42063 XM_044329288.1 4 0 0 15 16 NA NA NA NA NA NA 42064 XM_029324967.2 119 674 6524 69 6746 NA NA NA NA NA NA 42065 XM_044310621.1 0 0 0 0 18 NA NA NA NA NA NA 42066 XM_029328941.2 29 40 37 51 68 P0C872 2.76e-132 Bifunctional peptidase and (3S)-lysyl hydroxylase Jmjd7 (EC 1.14.11.63) (EC 3.4.-.-) (JmjC domain-containing protein 7) (Jumonji domain-containing protein 7) (L-lysine (3S)-hydroxylase Jmjd7) Mus musculus (Mouse) protein hydroxylation [GO:0018126]; proteolysis [GO:0006508] GO:0004175; GO:0004177; GO:0004497; GO:0005634; GO:0005737; GO:0006508; GO:0016706; GO:0018126; GO:0035064; GO:0046872; GO:0106155 42067 XM_044306994.1 28 0 34 124 28 NA NA NA NA NA NA 42068 XM_029334910.2 1045 1690 1443 4278 4080 NA NA NA NA NA NA 42069 XM_044324863.1 2093 241 64 1822 74 NA NA NA NA NA NA 42070 XM_044313924.1 98 57 38 261 118 NA NA NA NA NA NA 42071 XM_044327691.1 795 572 261 799 517 NA NA NA NA NA NA 42072 XR_006396801.1 0 0 0 28 0 NA NA NA NA NA NA 42073 XR_006394364.1 1366 704 932 1006 1167 Q9JHX4 1.84e-23 Caspase-8 (CASP-8) (EC 3.4.22.61) [Cleaved into: Caspase-8 subunit p18; Caspase-8 subunit p10] Rattus norvegicus (Rat) activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; execution phase of apoptosis [GO:0097194]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; heart development [GO:0007507]; hepatocyte apoptotic process [GO:0097284]; macrophage differentiation [GO:0030225]; necroptotic process [GO:0070266]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of necroptotic process [GO:0060546]; neural tube formation [GO:0001841]; positive regulation of apoptotic process [GO:0043065]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of neuron death [GO:1901216]; positive regulation of proteolysis [GO:0045862]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; pyroptosis [GO:0070269]; regulation of apoptotic signaling pathway [GO:2001233]; regulation of cytokine production [GO:0001817]; regulation of innate immune response [GO:0045088]; regulation of thymocyte apoptotic process [GO:0070243]; response to antibiotic [GO:0046677]; response to cobalt ion [GO:0032025]; response to cold [GO:0009409]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]; self proteolysis [GO:0097264]; TRAIL-activated apoptotic signaling pathway [GO:0036462] GO:0001525; GO:0001817; GO:0001841; GO:0004175; GO:0004197; GO:0005123; GO:0005164; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0006508; GO:0006915; GO:0006919; GO:0007507; GO:0008233; GO:0008303; GO:0008625; GO:0009409; GO:0016485; GO:0030225; GO:0030690; GO:0031264; GO:0031265; GO:0031625; GO:0032025; GO:0032355; GO:0032496; GO:0032731; GO:0032991; GO:0034612; GO:0035877; GO:0036462; GO:0042802; GO:0043005; GO:0043065; GO:0043123; GO:0043124; GO:0044297; GO:0044877; GO:0045088; GO:0045121; GO:0045471; GO:0045651; GO:0045862; GO:0046677; GO:0051603; GO:0060546; GO:0070243; GO:0070266; GO:0070269; GO:0071260; GO:0071407; GO:0097110; GO:0097153; GO:0097190; GO:0097191; GO:0097194; GO:0097199; GO:0097200; GO:0097202; GO:0097264; GO:0097284; GO:0097342; GO:1901216; GO:2001233; GO:2001238 42074 XR_006394364.1 1366 704 932 1006 1167 Q9JHX4 1.84e-23 Caspase-8 (CASP-8) (EC 3.4.22.61) [Cleaved into: Caspase-8 subunit p18; Caspase-8 subunit p10] Rattus norvegicus (Rat) activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; execution phase of apoptosis [GO:0097194]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; heart development [GO:0007507]; hepatocyte apoptotic process [GO:0097284]; macrophage differentiation [GO:0030225]; necroptotic process [GO:0070266]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of necroptotic process [GO:0060546]; neural tube formation [GO:0001841]; positive regulation of apoptotic process [GO:0043065]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of neuron death [GO:1901216]; positive regulation of proteolysis [GO:0045862]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; pyroptosis [GO:0070269]; regulation of apoptotic signaling pathway [GO:2001233]; regulation of cytokine production [GO:0001817]; regulation of innate immune response [GO:0045088]; regulation of thymocyte apoptotic process [GO:0070243]; response to antibiotic [GO:0046677]; response to cobalt ion [GO:0032025]; response to cold [GO:0009409]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]; self proteolysis [GO:0097264]; TRAIL-activated apoptotic signaling pathway [GO:0036462] GO:0001525; GO:0001817; GO:0001841; GO:0004175; GO:0004197; GO:0005123; GO:0005164; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0006508; GO:0006915; GO:0006919; GO:0007507; GO:0008233; GO:0008303; GO:0008625; GO:0009409; GO:0016485; GO:0030225; GO:0030690; GO:0031264; GO:0031265; GO:0031625; GO:0032025; GO:0032355; GO:0032496; GO:0032731; GO:0032991; GO:0034612; GO:0035877; GO:0036462; GO:0042802; GO:0043005; GO:0043065; GO:0043123; GO:0043124; GO:0044297; GO:0044877; GO:0045088; GO:0045121; GO:0045471; GO:0045651; GO:0045862; GO:0046677; GO:0051603; GO:0060546; GO:0070243; GO:0070266; GO:0070269; GO:0071260; GO:0071407; GO:0097110; GO:0097153; GO:0097190; GO:0097191; GO:0097194; GO:0097199; GO:0097200; GO:0097202; GO:0097264; GO:0097284; GO:0097342; GO:1901216; GO:2001233; GO:2001238 42075 XM_044315526.1 6 5 1 3 17 NA NA NA NA NA NA 42076 XM_029326082.2 6 15 26 0 109 NA NA NA NA NA NA 42077 XM_029343820.2 888 576 587 980 746 P25054 1.98e-114 Adenomatous polyposis coli protein (Protein APC) (Deleted in polyposis 2.5) Homo sapiens (Human) bicellular tight junction assembly [GO:0070830]; cell adhesion [GO:0007155]; cell fate specification [GO:0001708]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; endocardial cushion morphogenesis [GO:0003203]; heart valve development [GO:0003170]; insulin receptor signaling pathway [GO:0008286]; mitotic cytokinesis [GO:0000281]; mitotic spindle assembly checkpoint signaling [GO:0007094]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell cycle G1/S phase transition [GO:1902807]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of microtubule depolymerization [GO:0007026]; nervous system development [GO:0007399]; pattern specification process [GO:0007389]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration [GO:0030335]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein localization to centrosome [GO:1904781]; positive regulation of pseudopodium assembly [GO:0031274]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein-containing complex assembly [GO:0065003]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell differentiation [GO:0045595]; regulation of microtubule-based process [GO:0032886]; Wnt signaling pathway [GO:0016055] GO:0000281; GO:0000776; GO:0001708; GO:0003170; GO:0003203; GO:0005634; GO:0005654; GO:0005737; GO:0005794; GO:0005813; GO:0005829; GO:0005874; GO:0005886; GO:0005912; GO:0005923; GO:0006974; GO:0007026; GO:0007094; GO:0007155; GO:0007389; GO:0007399; GO:0008013; GO:0008017; GO:0008285; GO:0008286; GO:0010942; GO:0016055; GO:0016328; GO:0016342; GO:0016477; GO:0019887; GO:0019901; GO:0030027; GO:0030335; GO:0030877; GO:0031274; GO:0031625; GO:0032587; GO:0032886; GO:0043065; GO:0043161; GO:0045295; GO:0045595; GO:0045732; GO:0045736; GO:0048471; GO:0051010; GO:0051988; GO:0065003; GO:0070830; GO:0070840; GO:0090090; GO:0120162; GO:1902807; GO:1904781; GO:1990909; GO:2000134 42078 XM_044307426.1 144 64 85 136 156 Q9H0H3 1.12e-38 Kelch-like protein 25 (Ectoderm-neural cortex protein 2) (ENC-2) Homo sapiens (Human) negative regulation of fatty acid biosynthetic process [GO:0045717]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation [GO:0032831]; positive regulation of fatty acid oxidation [GO:0046321]; protein ubiquitination [GO:0016567]; regulation of translational initiation [GO:0006446]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0005737; GO:0005829; GO:0006446; GO:0006511; GO:0016567; GO:0031463; GO:0032831; GO:0045717; GO:0046321; GO:1990756 42079 XM_029328454.2 1611 1252 631 918 1142 NA NA NA NA NA NA 42080 XM_029355426.2 20 0 8 0 14 NA NA NA NA NA NA 42081 XM_044328588.1 31 3 5 14 81 O15439 8.17e-110 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 42082 XM_044315312.1 0 0 6 6 0 NA NA NA NA NA NA 42083 XM_044313336.1 26 5 3 43 10 NA NA NA NA NA NA 42084 XR_006393266.1 699 2342 678 942 1035 NA NA NA NA NA NA 42085 XR_006392378.1 1127 1179 800 2816 981 NA NA NA NA NA NA 42086 XM_029349647.2 44 13 0 7 28 P04323 4.88e-57 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 42087 XM_029349647.2 44 13 0 7 28 P04323 4.88e-57 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 42088 XM_029343908.2 133 0 0 0 63 Q96RW7 2.48e-70 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 42089 XM_029343908.2 133 0 0 0 63 Q96RW7 5.64e-66 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 42090 XM_029343908.2 133 0 0 0 63 Q96RW7 7.95e-65 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 42091 XM_029343908.2 133 0 0 0 63 Q96RW7 1.12e-63 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 42092 XM_029343908.2 133 0 0 0 63 Q96RW7 1.09e-62 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 42093 XM_029343908.2 133 0 0 0 63 Q96RW7 9.01e-52 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 42094 XM_029343908.2 133 0 0 0 63 Q96RW7 7.34e-49 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 42095 XM_029343908.2 133 0 0 0 63 Q96RW7 1.65e-48 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 42096 XM_029351571.2 631 289 294 302 441 NA NA NA NA NA NA 42097 XM_044314178.1 8 32 0 15 0 P51955 1.1e-141 Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis A-related kinase 2) (NimA-related protein kinase 2) (NimA-like protein kinase 1) Homo sapiens (Human) blastocyst development [GO:0001824]; cell division [GO:0051301]; centrosome separation [GO:0051299]; chromosome segregation [GO:0007059]; meiotic cell cycle [GO:0051321]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly [GO:0090307]; negative regulation of centriole-centriole cohesion [GO:1903126]; negative regulation of DNA binding [GO:0043392]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of mitotic centrosome separation [GO:0046602]; regulation of mitotic nuclear division [GO:0007088]; spindle assembly [GO:0051225] GO:0000070; GO:0000278; GO:0000776; GO:0000794; GO:0000922; GO:0001824; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005813; GO:0005829; GO:0005874; GO:0006468; GO:0007059; GO:0007088; GO:0019903; GO:0030496; GO:0032212; GO:0032991; GO:0043392; GO:0046602; GO:0046777; GO:0046872; GO:0051225; GO:0051299; GO:0051301; GO:0051321; GO:0051973; GO:0051988; GO:0090307; GO:0106310; GO:1903126; GO:1904355 42098 XR_006394518.1 46 23 30 85 54 NA NA NA NA NA NA 42099 XM_029344052.2 10 1 1 0 16 NA NA NA NA NA NA 42100 XM_044328526.1 436 141 159 82 410 NA NA NA NA NA NA 42101 XM_044325818.1 54 7 4 7 26 NA NA NA NA NA NA 42102 XM_029338989.2 302 133 66 137 115 Q55CD9 2.42e-125 Probable NADH dehydrogenase (EC 7.1.1.2) Dictyostelium discoideum (Social amoeba) NADH oxidation [GO:0006116] GO:0006116; GO:0008137 42103 XM_029334659.2 1043 388 967 800 389 NA NA NA NA NA NA 42104 XM_029333099.2 548 548 331 445 374 B1AS42 1.49e-75 NADH-cytochrome b5 reductase-like (EC 1.6.2.2) Mus musculus (Mouse) NA GO:0004128; GO:0005654 42105 XM_029331066.2 1391 1577 771 878 791 A6QQ21 1.4e-135 COP9 signalosome complex subunit 6 (SGN6) (Signalosome subunit 6) Bos taurus (Bovine) protein deneddylation [GO:0000338] GO:0000338; GO:0005737; GO:0008180; GO:0008237 42106 XM_029343814.2 458 904 212 383 320 A1L243 2.27e-35 LRP chaperone MESD (LDLR chaperone MESD) (Mesoderm development candidate 2) (Mesoderm development protein) Danio rerio (Zebrafish) (Brachydanio rerio) positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; protein folding [GO:0006457]; Wnt signaling pathway [GO:0016055] GO:0005783; GO:0006457; GO:0016055; GO:1904395 42107 XM_044326390.1 0 0 0 269 1 NA NA NA NA NA NA 42108 XM_044316231.1 94 87 85 487 228 NA NA NA NA NA NA 42109 XM_044312469.1 6 0 4 0 17 NA NA NA NA NA NA 42110 XR_006395794.1 89 94 48 55 41 NA NA NA NA NA NA 42111 XM_029338423.2 109 83 79 103 212 NA NA NA NA NA NA 42112 XM_029342504.2 34 0 39 9 54 P67829 6.79e-96 Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1) Ovis aries (Sheep) cell cycle [GO:0007049]; cell division [GO:0051301]; intermediate filament cytoskeleton organization [GO:0045104]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; protein phosphorylation [GO:0006468]; Wnt signaling pathway [GO:0016055] GO:0000776; GO:0004672; GO:0004674; GO:0005524; GO:0005819; GO:0005829; GO:0006468; GO:0007049; GO:0016055; GO:0016607; GO:0036064; GO:0045104; GO:0051301; GO:0106310; GO:1900226 42113 XM_029331289.2 1440 1343 848 1327 1491 Q6GQB5 3.18e-32 Akirin-2 (XAkirin2) Xenopus laevis (African clawed frog) neurogenesis [GO:0022008]; protein transport [GO:0015031] GO:0005634; GO:0015031; GO:0022008; GO:0030674 42114 XM_044326369.1 1587 1070 1158 1749 1537 Q6ZV73 1.98e-136 FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cytoskeleton organization [GO:0007010]; filopodium assembly [GO:0046847]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087] GO:0001726; GO:0005085; GO:0005737; GO:0005794; GO:0005856; GO:0007010; GO:0008360; GO:0030027; GO:0030036; GO:0031267; GO:0043087; GO:0046847; GO:0046872 42115 XM_044319761.1 28 46 36 48 12 Q86V88 4.36e-49 Magnesium-dependent phosphatase 1 (MDP-1) (EC 3.1.3.-) (EC 3.1.3.48) Homo sapiens (Human) NA GO:0003993; GO:0004725; GO:0046872 42116 XR_006397765.1 0 0 6 0 0 NA NA NA NA NA NA 42117 XM_044317146.1 121 32 91 100 266 NA NA NA NA NA NA 42118 XM_029357782.2 5945 4206 2989 4357 4240 P58465 1.89e-103 CTD small phosphatase-like protein (CTDSP-like) (EC 3.1.3.16) (Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3) (NIF-like protein) (Nuclear LIM interactor-interacting factor 1) (NLI-interacting factor 1) (Small C-terminal domain phosphatase 3) (SCP3) (Small CTD phosphatase 3) Mus musculus (Mouse) negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of protein phosphorylation [GO:0001933] GO:0001933; GO:0004721; GO:0005634; GO:0008420; GO:0017018; GO:0046872; GO:2000134 42119 XM_044307461.1 0 13 2 0 1 NA NA NA NA NA NA 42120 XM_044318925.1 146 166 89 97 150 NA NA NA NA NA NA 42121 XM_044312304.1 12 19 6 24 27 Q9Z2V5 8.67e-101 Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Histone deacetylase mHDA2) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-) Mus musculus (Mouse) aggresome assembly [GO:0070842]; axonal transport of mitochondrion [GO:0019896]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to misfolded protein [GO:0071218]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to topologically incorrect protein [GO:0035967]; cilium disassembly [GO:0061523]; collateral sprouting [GO:0048668]; dendritic spine morphogenesis [GO:0060997]; epigenetic regulation of gene expression [GO:0040029]; histone deacetylation [GO:0016575]; Hsp90 deacetylation [GO:0070846]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; mitochondrion localization [GO:0051646]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of protein-containing complex disassembly [GO:0043242]; negative regulation of proteolysis [GO:0045861]; negative regulation of transcription by RNA polymerase II [GO:0000122]; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:0061734]; peptidyl-lysine deacetylation [GO:0034983]; polyubiquitinated misfolded protein transport [GO:0070845]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of hydrogen peroxide-mediated programmed cell death [GO:1901300]; positive regulation of mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of tubulin deacetylation [GO:0090044]; protein deacetylation [GO:0006476]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; protein-containing complex disassembly [GO:0032984]; regulation of establishment of protein localization [GO:0070201]; regulation of fat cell differentiation [GO:0045598]; regulation of macroautophagy [GO:0016241]; regulation of mitochondrion organization [GO:0010821]; regulation of protein stability [GO:0031647]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]; response to dexamethasone [GO:0071548]; response to growth factor [GO:0070848]; response to immobilization stress [GO:0035902]; response to misfolded protein [GO:0051788]; tubulin deacetylation [GO:0090042]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] GO:0000118; GO:0000122; GO:0000209; GO:0000978; GO:0001222; GO:0001975; GO:0003779; GO:0004407; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0005829; GO:0005874; GO:0005875; GO:0005901; GO:0006476; GO:0006511; GO:0006515; GO:0006886; GO:0007026; GO:0008013; GO:0008017; GO:0008270; GO:0010634; GO:0010821; GO:0015630; GO:0016234; GO:0016235; GO:0016241; GO:0016575; GO:0019896; GO:0030424; GO:0030425; GO:0031252; GO:0031333; GO:0031593; GO:0031625; GO:0031647; GO:0031648; GO:0032418; GO:0032984; GO:0032991; GO:0033138; GO:0033558; GO:0034983; GO:0035902; GO:0035967; GO:0036064; GO:0040029; GO:0042826; GO:0042903; GO:0043005; GO:0043014; GO:0043025; GO:0043130; GO:0043162; GO:0043204; GO:0043242; GO:0045598; GO:0045861; GO:0048156; GO:0048471; GO:0048487; GO:0048668; GO:0048843; GO:0050775; GO:0051412; GO:0051646; GO:0051787; GO:0051788; GO:0051879; GO:0051968; GO:0060997; GO:0061523; GO:0061734; GO:0070201; GO:0070301; GO:0070840; GO:0070842; GO:0070845; GO:0070846; GO:0070848; GO:0071218; GO:0071374; GO:0071548; GO:0090042; GO:0090044; GO:0098779; GO:1901300; GO:1901984; GO:1903223; GO:1904056; GO:1904115; GO:2000273 42122 XM_044312304.1 12 19 6 24 27 Q9Z2V5 3.62e-89 Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Histone deacetylase mHDA2) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-) Mus musculus (Mouse) aggresome assembly [GO:0070842]; axonal transport of mitochondrion [GO:0019896]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to misfolded protein [GO:0071218]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to topologically incorrect protein [GO:0035967]; cilium disassembly [GO:0061523]; collateral sprouting [GO:0048668]; dendritic spine morphogenesis [GO:0060997]; epigenetic regulation of gene expression [GO:0040029]; histone deacetylation [GO:0016575]; Hsp90 deacetylation [GO:0070846]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; mitochondrion localization [GO:0051646]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of protein-containing complex disassembly [GO:0043242]; negative regulation of proteolysis [GO:0045861]; negative regulation of transcription by RNA polymerase II [GO:0000122]; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:0061734]; peptidyl-lysine deacetylation [GO:0034983]; polyubiquitinated misfolded protein transport [GO:0070845]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of hydrogen peroxide-mediated programmed cell death [GO:1901300]; positive regulation of mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of tubulin deacetylation [GO:0090044]; protein deacetylation [GO:0006476]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; protein-containing complex disassembly [GO:0032984]; regulation of establishment of protein localization [GO:0070201]; regulation of fat cell differentiation [GO:0045598]; regulation of macroautophagy [GO:0016241]; regulation of mitochondrion organization [GO:0010821]; regulation of protein stability [GO:0031647]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]; response to dexamethasone [GO:0071548]; response to growth factor [GO:0070848]; response to immobilization stress [GO:0035902]; response to misfolded protein [GO:0051788]; tubulin deacetylation [GO:0090042]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162] GO:0000118; GO:0000122; GO:0000209; GO:0000978; GO:0001222; GO:0001975; GO:0003779; GO:0004407; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0005829; GO:0005874; GO:0005875; GO:0005901; GO:0006476; GO:0006511; GO:0006515; GO:0006886; GO:0007026; GO:0008013; GO:0008017; GO:0008270; GO:0010634; GO:0010821; GO:0015630; GO:0016234; GO:0016235; GO:0016241; GO:0016575; GO:0019896; GO:0030424; GO:0030425; GO:0031252; GO:0031333; GO:0031593; GO:0031625; GO:0031647; GO:0031648; GO:0032418; GO:0032984; GO:0032991; GO:0033138; GO:0033558; GO:0034983; GO:0035902; GO:0035967; GO:0036064; GO:0040029; GO:0042826; GO:0042903; GO:0043005; GO:0043014; GO:0043025; GO:0043130; GO:0043162; GO:0043204; GO:0043242; GO:0045598; GO:0045861; GO:0048156; GO:0048471; GO:0048487; GO:0048668; GO:0048843; GO:0050775; GO:0051412; GO:0051646; GO:0051787; GO:0051788; GO:0051879; GO:0051968; GO:0060997; GO:0061523; GO:0061734; GO:0070201; GO:0070301; GO:0070840; GO:0070842; GO:0070845; GO:0070846; GO:0070848; GO:0071218; GO:0071374; GO:0071548; GO:0090042; GO:0090044; GO:0098779; GO:1901300; GO:1901984; GO:1903223; GO:1904056; GO:1904115; GO:2000273 42123 XM_029330820.2 6750 6840 5936 8343 10695 B5X4H8 1.3e-101 Riboflavin transporter 2 (RFT2) Salmo salar (Atlantic salmon) NA GO:0005886; GO:0032217 42124 XM_029351625.2 492 539 404 387 429 A3KPP4 1.13e-112 Solute carrier family 25 member 35 Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005743 42125 XM_029340707.2 0 0 0 0 12 NA NA NA NA NA NA 42126 XM_029342439.2 615 459 126 500 504 Q5SSZ7 1.22e-95 E3 ubiquitin-protein ligase ZNRF3 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase ZNRF3) (Zinc/RING finger protein 3) Mus musculus (Mouse) limb development [GO:0060173]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of Wnt signaling pathway [GO:0030178]; protein ubiquitination [GO:0016567]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; stem cell proliferation [GO:0072089]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt receptor catabolic process [GO:0038018]; Wnt signaling pathway [GO:0016055] GO:0004842; GO:0005109; GO:0005886; GO:0006511; GO:0016055; GO:0016567; GO:0030178; GO:0038018; GO:0046872; GO:0060173; GO:0060828; GO:0061630; GO:0072089; GO:0090090; GO:2000051; GO:2000095 42127 XM_029338783.2 168 136 45 139 98 NA NA NA NA NA NA 42128 XR_006394190.1 172 59 126 84 112 NA NA NA NA NA NA 42129 XM_044312632.1 86 57 102 10 146 Q6DCF2 1.62e-138 MMS19 nucleotide excision repair protein homolog (MMS19-like protein) Xenopus laevis (African clawed frog) cellular response to DNA damage stimulus [GO:0006974]; DNA metabolic process [GO:0006259]; DNA repair [GO:0006281]; iron-sulfur cluster assembly [GO:0016226]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; protein maturation by iron-sulfur cluster transfer [GO:0097428] GO:0005634; GO:0005737; GO:0005819; GO:0006259; GO:0006281; GO:0006974; GO:0016226; GO:0097361; GO:0097428; GO:1905168 42130 XM_044311162.1 0 0 19 0 0 NA NA NA NA NA NA 42131 XM_029355896.2 6 9 4 16 17 P02599 1.37e-29 Calmodulin (CaM) Dictyostelium discoideum (Social amoeba) establishment of protein localization to vacuole [GO:0072666]; mitotic cytokinesis [GO:0000281]; negative regulation of asexual reproduction [GO:1903665]; negative regulation of proteolysis [GO:0045861]; plasma membrane repair [GO:0001778]; positive regulation of ATP-dependent activity [GO:0032781]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of positive chemotaxis to cAMP [GO:0061122]; positive regulation of sequestering of calcium ion [GO:0051284]; protein export from nucleus [GO:0006611]; regulation of sorocarp stalk cell differentiation [GO:0031285] GO:0000281; GO:0000331; GO:0001778; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0006611; GO:0017024; GO:0019887; GO:0019900; GO:0019901; GO:0030234; GO:0031012; GO:0031013; GO:0031285; GO:0032781; GO:0045861; GO:0048306; GO:0050839; GO:0051284; GO:0051343; GO:0061122; GO:0072666; GO:1903665 42132 XM_044313834.1 2 19 27 33 49 NA NA NA NA NA NA 42133 XR_006392479.1 244 245 215 219 423 NA NA NA NA NA NA 42134 XM_044326457.1 38 2 8 0 31 NA NA NA NA NA NA 42135 XM_044308902.1 994 663 628 1087 849 P09759 3.32e-159 Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (Tyrosine-protein kinase receptor EPH-2) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; axon guidance [GO:0007411]; camera-type eye morphogenesis [GO:0048593]; cell chemotaxis [GO:0060326]; cell-substrate adhesion [GO:0031589]; central nervous system projection neuron axonogenesis [GO:0021952]; cranial nerve development [GO:0021545]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; ephrin receptor signaling pathway [GO:0048013]; establishment of cell polarity [GO:0030010]; hindbrain tangential cell migration [GO:0021934]; immunological synapse formation [GO:0001771]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of satellite cell differentiation [GO:1902725]; negative regulation of skeletal muscle satellite cell proliferation [GO:1902723]; neural precursor cell proliferation [GO:0061351]; neurogenesis [GO:0022008]; optic nerve morphogenesis [GO:0021631]; positive regulation of kinase activity [GO:0033674]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of neuron death [GO:1901214]; retinal ganglion cell axon guidance [GO:0031290]; skeletal muscle satellite cell activation [GO:0014719]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0001525; GO:0001771; GO:0004713; GO:0004714; GO:0005005; GO:0005524; GO:0005737; GO:0005783; GO:0005829; GO:0005886; GO:0007169; GO:0007411; GO:0008046; GO:0014719; GO:0016020; GO:0021545; GO:0021631; GO:0021934; GO:0021952; GO:0022008; GO:0030010; GO:0030424; GO:0030425; GO:0031290; GO:0031589; GO:0031901; GO:0032433; GO:0033674; GO:0043005; GO:0043235; GO:0044877; GO:0045121; GO:0046328; GO:0046777; GO:0048013; GO:0048593; GO:0050804; GO:0050965; GO:0051965; GO:0060326; GO:0060996; GO:0060997; GO:0061351; GO:0070372; GO:0098978; GO:1901214; GO:1902723; GO:1902725 42136 XM_029339053.2 127 54 0 49 110 O08912 1.43e-158 Polypeptide N-acetylgalactosaminyltransferase 1 (EC 2.4.1.41) (Polypeptide GalNAc transferase 1) (GalNAc-T1) (pp-GaNTase 1) (Protein-UDP acetylgalactosaminyltransferase 1) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 1) [Cleaved into: Polypeptide N-acetylgalactosaminyltransferase 1 soluble form] Mus musculus (Mouse) protein O-linked glycosylation [GO:0006493]; protein O-linked glycosylation via serine [GO:0018242]; protein O-linked glycosylation via threonine [GO:0018243] GO:0004653; GO:0005576; GO:0005794; GO:0006493; GO:0018242; GO:0018243; GO:0030145; GO:0030246; GO:0032580; GO:0048471 42137 XM_044317677.1 1668 1281 1326 1867 2127 Q640Z6 9.42e-21 Nuclear pore complex protein Nup153 (153 kDa nucleoporin) (Nucleoporin Nup153) Xenopus laevis (African clawed frog) mRNA transport [GO:0051028]; nuclear pore complex assembly [GO:0051292]; protein transport [GO:0015031] GO:0003677; GO:0005643; GO:0015031; GO:0031965; GO:0046872; GO:0051028; GO:0051292 42138 XM_029331363.2 2770 3103 2088 2464 1836 Q8C811 3.13e-94 Solute carrier family 35 member E2A Mus musculus (Mouse) blastocyst hatching [GO:0001835] GO:0001835; GO:0005794; GO:0015297; GO:0016020 42139 XR_006397238.1 4 64 0 0 0 NA NA NA NA NA NA 42140 XM_044328928.1 162 3 16 0 0 Q15822 9.29e-88 Neuronal acetylcholine receptor subunit alpha-2 Homo sapiens (Human) cellular response to nicotine [GO:0071316]; chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; membrane depolarization [GO:0051899]; modulation of inhibitory postsynaptic potential [GO:0098828]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; response to acetylcholine [GO:1905144]; response to nicotine [GO:0035094]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271] GO:0005231; GO:0005654; GO:0005886; GO:0005892; GO:0006811; GO:0007165; GO:0007268; GO:0007271; GO:0015464; GO:0016020; GO:0022848; GO:0030594; GO:0034220; GO:0035094; GO:0042391; GO:0043005; GO:0045171; GO:0045202; GO:0045211; GO:0050877; GO:0050997; GO:0051899; GO:0071316; GO:0098828; GO:0120111; GO:1901363; GO:1904315; GO:1905144 42141 XM_044309765.1 28 3 29 278 150 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 42142 XM_044309765.1 28 3 29 278 150 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 42143 XM_044309765.1 28 3 29 278 150 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 42144 XM_044309765.1 28 3 29 278 150 P07207 1.24e-175 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 42145 XM_044309765.1 28 3 29 278 150 P07207 1.64e-131 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 42146 XM_044309765.1 28 3 29 278 150 P07207 2.29e-118 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 42147 XM_029329627.2 2043 1169 1071 2059 2321 Q99PV3 0 Muskelin Rattus norvegicus (Rat) actin cytoskeleton reorganization [GO:0031532]; cell-matrix adhesion [GO:0007160]; regulation of cell shape [GO:0008360]; regulation of receptor internalization [GO:0002090] GO:0000151; GO:0001726; GO:0002090; GO:0005654; GO:0005737; GO:0005829; GO:0005938; GO:0007160; GO:0008360; GO:0031532; GO:0042802; GO:0042803; GO:0098794 42148 XM_029325723.2 636 376 371 471 710 Q5HYC2 1.01e-65 Uncharacterized protein KIAA2026 Homo sapiens (Human) NA NA 42149 XM_029351361.2 0 121 115 10 105 Q63ZU0 1.32e-100 Adenosine deaminase (EC 3.5.4.4) (Adenosine aminohydrolase) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) adenosine catabolic process [GO:0006154]; inosine biosynthetic process [GO:0046103]; nucleotide metabolic process [GO:0009117]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168] GO:0004000; GO:0005764; GO:0005886; GO:0006154; GO:0008270; GO:0009117; GO:0009168; GO:0046103; GO:0046936; GO:0060205; GO:0070161 42150 XM_029345459.2 106 84 0 0 166 Q8N2E2 1.61e-39 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 42151 XM_029345459.2 106 84 0 0 166 Q8N2E2 9.75e-38 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 42152 XM_029345459.2 106 84 0 0 166 Q8N2E2 1.73e-36 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 42153 XM_029345459.2 106 84 0 0 166 Q8N2E2 5.41e-35 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 42154 XM_029345459.2 106 84 0 0 166 Q8N2E2 6.34e-32 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 42155 XM_029345459.2 106 84 0 0 166 Q8N2E2 4.61e-25 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 42156 XM_029337409.2 66 12 38 0 137 Q9BS34 9.47e-30 Zinc finger protein 670 Homo sapiens (Human) cellular lipid metabolic process [GO:0044255]; lipid metabolic process [GO:0006629]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0006629; GO:0044255; GO:0046872 42157 XM_029337409.2 66 12 38 0 137 Q9BS34 4.88e-28 Zinc finger protein 670 Homo sapiens (Human) cellular lipid metabolic process [GO:0044255]; lipid metabolic process [GO:0006629]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0006629; GO:0044255; GO:0046872 42158 XM_029337409.2 66 12 38 0 137 Q9BS34 2.23e-25 Zinc finger protein 670 Homo sapiens (Human) cellular lipid metabolic process [GO:0044255]; lipid metabolic process [GO:0006629]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0006629; GO:0044255; GO:0046872 42159 XM_029337409.2 66 12 38 0 137 Q9BS34 2.71e-25 Zinc finger protein 670 Homo sapiens (Human) cellular lipid metabolic process [GO:0044255]; lipid metabolic process [GO:0006629]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0006629; GO:0044255; GO:0046872 42160 XM_044306853.1 4737 2478 1464 2577 1359 NA NA NA NA NA NA 42161 XM_029356323.2 1427 1618 1117 1276 518 NA NA NA NA NA NA 42162 XM_029356766.2 258 333 344 327 388 Q7YRC1 4.66e-84 AH receptor-interacting protein (AIP) (Aryl-hydrocarbon receptor-interacting protein) Bos taurus (Bovine) xenobiotic metabolic process [GO:0006805] GO:0003712; GO:0003755; GO:0005737; GO:0006805 42163 XM_029328278.2 534 346 81 49 146 Q5ZJP7 7.82e-28 BTB/POZ domain-containing protein KCTD7 Gallus gallus (Chicken) membrane hyperpolarization [GO:0060081]; positive regulation of transporter activity [GO:0032411]; protein homooligomerization [GO:0051260] GO:0005829; GO:0005886; GO:0032411; GO:0051260; GO:0060081 42164 XR_006397028.1 36 6 234 94 230 NA NA NA NA NA NA 42165 XM_029339787.2 192 48 59 164 211 Q5PQ50 2.76e-73 Acyl-coenzyme A diphosphatase NUDT19 (EC 3.6.1.-) (Nucleoside diphosphate-linked moiety X motif 19) (Nudix motif 19) Xenopus laevis (African clawed frog) butyryl-CoA catabolic process [GO:0044580]; coenzyme A catabolic process [GO:0015938]; malonyl-CoA catabolic process [GO:2001294]; medium-chain fatty-acyl-CoA catabolic process [GO:0036114]; propionyl-CoA metabolic process [GO:1902858]; succinyl-CoA catabolic process [GO:1901289] GO:0000287; GO:0005777; GO:0015938; GO:0036114; GO:0044580; GO:0106399; GO:1901289; GO:1902858; GO:2001294 42166 XM_029330499.2 15 0 0 0 38 NA NA NA NA NA NA 42167 XM_044318499.1 308 28 127 117 137 NA NA NA NA NA NA 42168 XM_044309977.1 17 0 25 4 13 NA NA NA NA NA NA 42169 XM_029333527.2 89 157 71 199 93 Q9WVF7 0 DNA polymerase epsilon catalytic subunit A (EC 2.7.7.7) (3'-5' exodeoxyribonuclease) (EC 3.1.11.-) (DNA polymerase II subunit A) Mus musculus (Mouse) base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; DNA replication proofreading [GO:0045004]; DNA synthesis involved in DNA repair [GO:0000731]; DNA-templated DNA replication [GO:0006261]; embryonic organ development [GO:0048568]; G1/S transition of mitotic cell cycle [GO:0000082]; leading strand elongation [GO:0006272]; mitotic cell cycle [GO:0000278]; nucleotide-excision repair, DNA gap filling [GO:0006297] GO:0000082; GO:0000166; GO:0000278; GO:0000731; GO:0003677; GO:0003682; GO:0003887; GO:0005634; GO:0005654; GO:0005886; GO:0006260; GO:0006261; GO:0006272; GO:0006287; GO:0006297; GO:0008270; GO:0008310; GO:0008622; GO:0045004; GO:0048568; GO:0051539; GO:0071897 42170 XM_029336284.2 1191 798 485 1001 1349 P55265 7.8e-94 Double-stranded RNA-specific adenosine deaminase (DRADA) (EC 3.5.4.37) (136 kDa double-stranded RNA-binding protein) (p136) (Interferon-inducible protein 4) (IFI-4) (K88DSRBP) Homo sapiens (Human) adenosine to inosine editing [GO:0006382]; base conversion or substitution editing [GO:0016553]; cellular response to virus [GO:0098586]; defense response to virus [GO:0051607]; definitive hemopoiesis [GO:0060216]; erythrocyte differentiation [GO:0030218]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell homeostasis [GO:0061484]; hepatocyte apoptotic process [GO:0097284]; innate immune response [GO:0045087]; mRNA processing [GO:0006397]; negative regulation of hepatocyte apoptotic process [GO:1903944]; negative regulation of post-transcriptional gene silencing by RNA [GO:1900369]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; osteoblast differentiation [GO:0001649]; positive regulation of viral genome replication [GO:0045070]; pre-miRNA processing [GO:0031054]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; response to interferon-alpha [GO:0035455]; response to virus [GO:0009615]; RISC complex assembly [GO:0070922]; RNA processing [GO:0006396]; somatic diversification of immune receptors via somatic mutation [GO:0002566] GO:0001649; GO:0002244; GO:0002566; GO:0003677; GO:0003723; GO:0003725; GO:0003726; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0006382; GO:0006396; GO:0006397; GO:0006606; GO:0006611; GO:0008251; GO:0009615; GO:0016020; GO:0016553; GO:0030218; GO:0031054; GO:0035455; GO:0044387; GO:0044530; GO:0045070; GO:0045087; GO:0046872; GO:0051607; GO:0060216; GO:0060339; GO:0061484; GO:0070922; GO:0097284; GO:0098586; GO:1900369; GO:1903944 42171 XM_044321264.1 1981 1284 1136 2537 2118 A0A0R4IES7 0 Bridge-like lipid transfer protein family member 1 Danio rerio (Zebrafish) (Brachydanio rerio) endocytic recycling [GO:0032456]; endosomal transport [GO:0016197]; intermembrane lipid transfer [GO:0120009]; phagocytosis [GO:0006909]; synaptic vesicle endocytosis [GO:0048488] GO:0005789; GO:0005886; GO:0006909; GO:0016197; GO:0031966; GO:0032456; GO:0048488; GO:0098793; GO:0120009; GO:0140268; GO:1904121 42172 XM_044321264.1 1981 1284 1136 2537 2118 A0A0R4IES7 4.47e-157 Bridge-like lipid transfer protein family member 1 Danio rerio (Zebrafish) (Brachydanio rerio) endocytic recycling [GO:0032456]; endosomal transport [GO:0016197]; intermembrane lipid transfer [GO:0120009]; phagocytosis [GO:0006909]; synaptic vesicle endocytosis [GO:0048488] GO:0005789; GO:0005886; GO:0006909; GO:0016197; GO:0031966; GO:0032456; GO:0048488; GO:0098793; GO:0120009; GO:0140268; GO:1904121 42173 XM_044321264.1 1981 1284 1136 2537 2118 A0A0R4IES7 1.29e-106 Bridge-like lipid transfer protein family member 1 Danio rerio (Zebrafish) (Brachydanio rerio) endocytic recycling [GO:0032456]; endosomal transport [GO:0016197]; intermembrane lipid transfer [GO:0120009]; phagocytosis [GO:0006909]; synaptic vesicle endocytosis [GO:0048488] GO:0005789; GO:0005886; GO:0006909; GO:0016197; GO:0031966; GO:0032456; GO:0048488; GO:0098793; GO:0120009; GO:0140268; GO:1904121 42174 XM_044321264.1 1981 1284 1136 2537 2118 A0A0R4IES7 1.11e-55 Bridge-like lipid transfer protein family member 1 Danio rerio (Zebrafish) (Brachydanio rerio) endocytic recycling [GO:0032456]; endosomal transport [GO:0016197]; intermembrane lipid transfer [GO:0120009]; phagocytosis [GO:0006909]; synaptic vesicle endocytosis [GO:0048488] GO:0005789; GO:0005886; GO:0006909; GO:0016197; GO:0031966; GO:0032456; GO:0048488; GO:0098793; GO:0120009; GO:0140268; GO:1904121 42175 XR_006397029.1 303 77 32 197 136 NA NA NA NA NA NA 42176 XR_006393716.1 1174 1860 704 1716 413 NA NA NA NA NA NA 42177 XM_044318531.1 0 0 3 4 6 Q15818 7.42e-38 Neuronal pentraxin-1 (NP1) (Neuronal pentraxin I) (NP-I) Homo sapiens (Human) axonogenesis involved in innervation [GO:0060385]; cellular response to glucose stimulus [GO:0071333]; cellular response to potassium ion [GO:0035865]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; mitochondrial transport [GO:0006839]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic density assembly [GO:0097107]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962] GO:0005739; GO:0005886; GO:0006839; GO:0007268; GO:0007417; GO:0030133; GO:0035865; GO:0043005; GO:0043083; GO:0043653; GO:0046872; GO:0060385; GO:0071333; GO:0097107; GO:0098962; GO:0098978; GO:0099645 42178 XM_029329858.2 458 2 253 354 283 P20072 1.12e-70 Annexin A7 (Annexin VII) (Annexin-7) (Synexin) Bos taurus (Bovine) NA GO:0005509; GO:0005544; GO:0005634; GO:0005737; GO:0042584 42179 XR_006395198.1 137 500 138 127 255 NA NA NA NA NA NA 42180 XM_044322318.1 12 0 0 0 4 NA NA NA NA NA NA 42181 XM_029335379.2 10 4 14 2 150 O95841 3.31e-48 Angiopoietin-related protein 1 (Angiopoietin-3) (ANG-3) (Angiopoietin-like protein 1) Homo sapiens (Human) transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0005102; GO:0005615; GO:0007169; GO:0062023; GO:0070062 42182 XM_029342505.2 10 3 0 18 22 P67829 2.35e-80 Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1) Ovis aries (Sheep) cell cycle [GO:0007049]; cell division [GO:0051301]; intermediate filament cytoskeleton organization [GO:0045104]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; protein phosphorylation [GO:0006468]; Wnt signaling pathway [GO:0016055] GO:0000776; GO:0004672; GO:0004674; GO:0005524; GO:0005819; GO:0005829; GO:0006468; GO:0007049; GO:0016055; GO:0016607; GO:0036064; GO:0045104; GO:0051301; GO:0106310; GO:1900226 42183 XM_029347457.2 75 73 81 97 164 P48039 2.65e-23 Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor) Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; circadian rhythm [GO:0007623]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; mating behavior [GO:0007617] GO:0004930; GO:0005886; GO:0007186; GO:0007187; GO:0007193; GO:0007617; GO:0007623; GO:0008502; GO:0042562; GO:0043235; GO:0097159 42184 XR_006395156.1 332 78 61 105 249 B5DF45 1.12e-89 TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6) Rattus norvegicus (Rat) activation of NF-kappaB-inducing kinase activity [GO:0007250]; activation of protein kinase activity [GO:0032147]; animal organ morphogenesis [GO:0009887]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; bone remodeling [GO:0046849]; bone resorption [GO:0045453]; cell development [GO:0048468]; cellular response to cytokine stimulus [GO:0071345]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-17-mediated signaling pathway [GO:0097400]; JNK cascade [GO:0007254]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin production [GO:0002637]; response to interleukin-1 [GO:0070555]; response to ischemia [GO:0002931]; signal transduction [GO:0007165]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000122; GO:0000209; GO:0001503; GO:0001701; GO:0001843; GO:0002637; GO:0002726; GO:0002931; GO:0004842; GO:0005164; GO:0005634; GO:0005737; GO:0005811; GO:0005829; GO:0005886; GO:0005938; GO:0006955; GO:0006974; GO:0007165; GO:0007249; GO:0007250; GO:0007254; GO:0008270; GO:0009887; GO:0009898; GO:0016567; GO:0019221; GO:0019886; GO:0019901; GO:0030316; GO:0031435; GO:0031624; GO:0031625; GO:0031666; GO:0031996; GO:0032147; GO:0032735; GO:0032743; GO:0032755; GO:0032813; GO:0032991; GO:0033209; GO:0035631; GO:0042088; GO:0042102; GO:0042475; GO:0042802; GO:0042826; GO:0042981; GO:0043011; GO:0043122; GO:0043123; GO:0043422; GO:0043507; GO:0045453; GO:0045672; GO:0045892; GO:0045944; GO:0046330; GO:0046849; GO:0047485; GO:0048468; GO:0048471; GO:0048661; GO:0050852; GO:0051091; GO:0051092; GO:0051865; GO:0061630; GO:0070498; GO:0070534; GO:0070555; GO:0071222; GO:0071345; GO:0097400; GO:1901224; GO:1904996; GO:2000679 42185 XR_006395156.1 332 78 61 105 249 B5DF45 1.12e-89 TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6) Rattus norvegicus (Rat) activation of NF-kappaB-inducing kinase activity [GO:0007250]; activation of protein kinase activity [GO:0032147]; animal organ morphogenesis [GO:0009887]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; bone remodeling [GO:0046849]; bone resorption [GO:0045453]; cell development [GO:0048468]; cellular response to cytokine stimulus [GO:0071345]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-17-mediated signaling pathway [GO:0097400]; JNK cascade [GO:0007254]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin production [GO:0002637]; response to interleukin-1 [GO:0070555]; response to ischemia [GO:0002931]; signal transduction [GO:0007165]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000122; GO:0000209; GO:0001503; GO:0001701; GO:0001843; GO:0002637; GO:0002726; GO:0002931; GO:0004842; GO:0005164; GO:0005634; GO:0005737; GO:0005811; GO:0005829; GO:0005886; GO:0005938; GO:0006955; GO:0006974; GO:0007165; GO:0007249; GO:0007250; GO:0007254; GO:0008270; GO:0009887; GO:0009898; GO:0016567; GO:0019221; GO:0019886; GO:0019901; GO:0030316; GO:0031435; GO:0031624; GO:0031625; GO:0031666; GO:0031996; GO:0032147; GO:0032735; GO:0032743; GO:0032755; GO:0032813; GO:0032991; GO:0033209; GO:0035631; GO:0042088; GO:0042102; GO:0042475; GO:0042802; GO:0042826; GO:0042981; GO:0043011; GO:0043122; GO:0043123; GO:0043422; GO:0043507; GO:0045453; GO:0045672; GO:0045892; GO:0045944; GO:0046330; GO:0046849; GO:0047485; GO:0048468; GO:0048471; GO:0048661; GO:0050852; GO:0051091; GO:0051092; GO:0051865; GO:0061630; GO:0070498; GO:0070534; GO:0070555; GO:0071222; GO:0071345; GO:0097400; GO:1901224; GO:1904996; GO:2000679 42186 XM_029342323.2 36 17 47 92 28 NA NA NA NA NA NA 42187 XM_029327095.2 787 522 693 1293 890 Q09225 5.03e-71 Nose resistant to fluoxetine protein 6 (Protein nrf-6) Caenorhabditis elegans lipid transport [GO:0006869] GO:0006869; GO:0008289; GO:0016020; GO:0016747 42188 XM_029339640.2 60 82 29 87 111 O13023 7.31e-36 Hematopoietically-expressed homeobox protein hhex (Homeobox protein hex) (XHex) (Hhex-A protein) Xenopus laevis (African clawed frog) anterior/posterior pattern specification [GO:0009952]; embryonic hemopoiesis [GO:0035162]; heart development [GO:0007507]; liver development [GO:0001889]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of Wnt signaling pathway [GO:0030177]; vasculogenesis [GO:0001570]; Wnt signaling pathway [GO:0016055] GO:0000122; GO:0000981; GO:0001570; GO:0001889; GO:0005634; GO:0007507; GO:0009952; GO:0016055; GO:0030177; GO:0035162; GO:0043565; GO:0045892 42189 XM_029330299.2 366 217 214 213 354 NA NA NA NA NA NA 42190 XM_029331118.2 41 30 25 9 24 NA NA NA NA NA NA 42191 XM_044324052.1 1143 696 670 1214 1344 O43933 1.07e-171 Peroxisomal ATPase PEX1 (EC 3.6.4.-) (Peroxin-1) (Peroxisome biogenesis disorder protein 1) (Peroxisome biogenesis factor 1) Homo sapiens (Human) microtubule-based peroxisome localization [GO:0060152]; peroxisome organization [GO:0007031]; protein import into peroxisome matrix [GO:0016558]; protein import into peroxisome matrix, receptor recycling [GO:0016562]; protein targeting to peroxisome [GO:0006625]; protein unfolding [GO:0043335] GO:0005524; GO:0005737; GO:0005777; GO:0005778; GO:0005829; GO:0006625; GO:0007031; GO:0008022; GO:0016558; GO:0016562; GO:0016887; GO:0043335; GO:0044877; GO:0060152; GO:0070062; GO:0140036; GO:0140318 42192 XM_044312514.1 23 1 15 1 158 NA NA NA NA NA NA 42193 XR_006397456.1 19 1 0 1 31 NA NA NA NA NA NA 42194 XM_044310667.1 0 0 10 0 6 NA NA NA NA NA NA 42195 XM_044321034.1 638 517 277 574 563 NA NA NA NA NA NA 42196 XM_029330964.2 863 688 473 890 1121 P33277 8.18e-104 GTPase-activating protein (Ras GTPase-activating protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) negative regulation of Ras protein signal transduction [GO:0046580]; positive regulation of mating projection assembly [GO:1902917]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of GTPase activity [GO:0043087]; signal transduction involved in positive regulation of conjugation with cellular fusion [GO:0032005] GO:0000935; GO:0005096; GO:0005634; GO:0005737; GO:0005829; GO:0005937; GO:0005938; GO:0032005; GO:0032956; GO:0043087; GO:0046580; GO:0051285; GO:0071944; GO:0090726; GO:1902917 42197 XR_006397850.1 9 0 0 0 0 NA NA NA NA NA NA 42198 XM_044322469.1 99 62 1 0 8 Q96AY4 1.25e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 42199 XM_044322469.1 99 62 1 0 8 Q96AY4 3.32e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 42200 XM_044322469.1 99 62 1 0 8 Q96AY4 5.81e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 42201 XM_044322469.1 99 62 1 0 8 Q96AY4 9.72e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 42202 XM_029325052.2 114 30 24 50 39 Q6DH69 1.01e-131 Fatty-acid amide hydrolase 2-A (EC 3.5.1.99) Danio rerio (Zebrafish) (Brachydanio rerio) lipid catabolic process [GO:0016042] GO:0016020; GO:0016042; GO:0017064 42203 XR_006394856.1 67 10 97 45 30 Q8NI36 0 WD repeat-containing protein 36 (T-cell activation WD repeat-containing protein) (TA-WDRP) Homo sapiens (Human) response to stimulus [GO:0050896]; rRNA processing [GO:0006364]; visual perception [GO:0007601] GO:0003723; GO:0005654; GO:0005730; GO:0006364; GO:0007601; GO:0032040; GO:0034388; GO:0050896 42204 XM_044318534.1 710 77 220 13 275 P62296 0 Abnormal spindle-like microcephaly-associated protein homolog Saimiri boliviensis boliviensis (Bolivian squirrel monkey) cell cycle [GO:0007049]; cell division [GO:0051301]; cytoskeleton organization [GO:0007010] GO:0005516; GO:0005634; GO:0005737; GO:0005819; GO:0007010; GO:0007049; GO:0051301 42205 XM_044312663.1 5 0 1 0 6 NA NA NA NA NA NA 42206 XM_044326378.1 339 450 0 414 737 Q24270 0 Voltage-dependent calcium channel type D subunit alpha-1 (DmCa1D) Drosophila melanogaster (Fruit fly) calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; calcium-mediated signaling [GO:0019722]; epithelial fluid transport [GO:0042045]; locomotion [GO:0040011]; muscle contraction [GO:0006936]; neuron remodeling [GO:0016322]; regulation of ion transmembrane transport [GO:0034765] GO:0005245; GO:0005891; GO:0006816; GO:0006936; GO:0008331; GO:0016322; GO:0016323; GO:0016324; GO:0019722; GO:0034765; GO:0040011; GO:0042045; GO:0046872; GO:0070588; GO:0098703 42207 XM_044317148.1 1176 99 449 84 143 NA NA NA NA NA NA 42208 XM_044326276.1 18 24 37 33 42 NA NA NA NA NA NA 42209 XR_006391508.1 40 37 14 113 180 NA NA NA NA NA NA 42210 XM_029348408.2 3067 1703 504 1001 808 NA NA NA NA NA NA 42211 XM_029345677.2 441 201 572 531 1288 Q8K0Q5 3.4e-95 Rho GTPase-activating protein 18 (Rho-type GTPase-activating protein 18) Mus musculus (Mouse) regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin filament polymerization [GO:0030833]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of small GTPase mediated signal transduction [GO:0051056]; small GTPase mediated signal transduction [GO:0007264] GO:0001726; GO:0005096; GO:0005737; GO:0005829; GO:0005881; GO:0005886; GO:0007264; GO:0008360; GO:0016607; GO:0030833; GO:0032956; GO:0051056; GO:2000145 42212 XM_044315566.1 123 17 77 78 227 C3VPR6 8.07e-27 Protein NLRC5 Mus musculus (Mouse) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of type II interferon-mediated signaling pathway [GO:0060335]; regulation of kinase activity [GO:0043549]; response to bacterium [GO:0009617] GO:0000978; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0009617; GO:0032088; GO:0035556; GO:0043549; GO:0045087; GO:0045345; GO:0045944; GO:0051607; GO:0060335; GO:0060339; GO:0060340 42213 XM_029347402.2 557 325 248 750 237 O13267 4.56e-92 Protein Wnt-5a (PWnt-5a) Pleurodeles waltl (Iberian ribbed newt) anatomical structure development [GO:0048856]; Wnt signaling pathway [GO:0016055] GO:0005102; GO:0005576; GO:0016055; GO:0048856 42214 XM_044320474.1 2239 1099 1549 1949 2209 NA NA NA NA NA NA 42215 XM_044312407.1 0 5 15 23 12 NA NA NA NA NA NA 42216 XR_003826793.2 2073 2386 1642 1260 1965 NA NA NA NA NA NA 42217 XM_029356007.2 0 0 53 0 0 Q9JHE4 1.06e-54 Galactosylceramide sulfotransferase (GalCer sulfotransferase) (EC 2.8.2.11) (3'-phosphoadenosine-5'-phosphosulfate:GalCer sulfotransferase) (3'-phosphoadenylylsulfate:galactosylceramide 3'-sulfotransferase) (Cerebroside sulfotransferase) Mus musculus (Mouse) galactosylceramide biosynthetic process [GO:0006682]; galactosylceramide metabolic process [GO:0006681]; glycerolipid metabolic process [GO:0046486]; glycolipid biosynthetic process [GO:0009247]; myelination [GO:0042552]; spermatogenesis [GO:0007283]; sphingolipid metabolic process [GO:0006665] GO:0000139; GO:0001733; GO:0006665; GO:0006681; GO:0006682; GO:0007283; GO:0008146; GO:0009247; GO:0016020; GO:0042552; GO:0046486; GO:0050694 42218 XM_044325607.1 49 17 40 19 89 NA NA NA NA NA NA 42219 XM_029338637.2 324 258 131 50 43 NA NA NA NA NA NA 42220 XR_006391423.1 66 90 75 104 100 NA NA NA NA NA NA 42221 XM_044326646.1 63 66 23 70 30 NA NA NA NA NA NA 42222 XR_006393603.1 187 0 128 136 189 Q2TBP0 1.75e-112 Proteasome subunit beta type-7 (EC 3.4.25.1) Bos taurus (Bovine) proteolysis involved in protein catabolic process [GO:0051603] GO:0004298; GO:0005634; GO:0005737; GO:0005839; GO:0019774; GO:0051603 42223 XM_044308158.1 257 775 23 326 60 P00521 4.87e-28 Tyrosine-protein kinase transforming protein Abl (EC 2.7.10.2) (V-abl) Abelson murine leukemia virus NA GO:0004715; GO:0005524 42224 XM_029334560.2 165 38 37 59 19 F4JYJ3 1.03e-25 Phosphatidylinositol/phosphatidylcholine transfer protein SFH11 (Protein SEC FOURTEEN HOMOLOGS 11) (AtSFH11) Arabidopsis thaliana (Mouse-ear cress) protein transport [GO:0015031] GO:0000139; GO:0005886; GO:0015031 42225 XR_006395349.1 0 11 0 0 0 NA NA NA NA NA NA 42226 XM_044310211.1 4 0 0 0 27 NA NA NA NA NA NA 42227 XR_003825270.2 47 0 82 12 370 NA NA NA NA NA NA 42228 XM_044326116.1 113 178 114 211 270 NA NA NA NA NA NA 42229 XR_006393309.1 0 3 0 12 0 NA NA NA NA NA NA 42230 XR_006391517.1 13 6 18 36 65 NA NA NA NA NA NA 42231 XM_029334743.2 221 162 154 333 347 P97858 5.96e-117 Solute carrier family 35 member B1 (ATP/ADP exchanger ER) (AXER) (Endoplasmic reticulum ATP/ADP translocase) (UDP-galactose transporter-related protein 1) (UGTrel1) Mus musculus (Mouse) UDP-galactose transmembrane transport [GO:0072334] GO:0000139; GO:0005459; GO:0005460; GO:0005471; GO:0005789; GO:0022857; GO:0072334 42232 XM_029338000.2 37 237 77 1 55 NA NA NA NA NA NA 42233 XM_029336285.2 114 199 0 117 367 P48547 1.18e-115 Potassium voltage-gated channel subfamily C member 1 (NGK2) (Voltage-gated potassium channel subunit Kv3.1) (Voltage-gated potassium channel subunit Kv4) Homo sapiens (Human) cellular response to xenobiotic stimulus [GO:0071466]; cerebellum development [GO:0021549]; corpus callosum development [GO:0022038]; globus pallidus development [GO:0021759]; optic nerve development [GO:0021554]; positive regulation of voltage-gated potassium channel activity [GO:1903818]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; protein tetramerization [GO:0051262]; response to amine [GO:0014075]; response to auditory stimulus [GO:0010996]; response to fibroblast growth factor [GO:0071774]; response to light intensity [GO:0009642]; response to nerve growth factor [GO:1990089]; response to potassium ion [GO:0035864]; response to toxic substance [GO:0009636] GO:0005249; GO:0005251; GO:0005886; GO:0006813; GO:0008076; GO:0009636; GO:0009642; GO:0009986; GO:0010996; GO:0014075; GO:0016020; GO:0019894; GO:0021549; GO:0021554; GO:0021759; GO:0022038; GO:0030424; GO:0030673; GO:0032590; GO:0032809; GO:0035864; GO:0042734; GO:0044305; GO:0044325; GO:0045211; GO:0051260; GO:0051262; GO:0071466; GO:0071774; GO:0071805; GO:0099508; GO:1903818; GO:1990089 42234 XM_044316061.1 3703 6301 11441 1321 36 NA NA NA NA NA NA 42235 XM_029334473.2 843 346 421 431 878 NA NA NA NA NA NA 42236 XR_006394810.1 42 65 0 77 0 NA NA NA NA NA NA 42237 XM_044322492.1 48670 32994 15570 23971 11656 Q24133 3.45e-102 DnaJ protein homolog 1 (DROJ1) Drosophila melanogaster (Fruit fly) chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of crystal cell differentiation [GO:0042691]; protein folding [GO:0006457]; protein stabilization [GO:0050821]; response to heat [GO:0009408] GO:0000122; GO:0005829; GO:0006457; GO:0009408; GO:0042691; GO:0050821; GO:0051082; GO:0051085; GO:0051087; GO:0140297 42238 XM_029325026.2 0 4 2 1 8 O57422 1.51e-24 Melanopsin-B (Opsin-4B) (xMOP) Xenopus laevis (African clawed frog) phototransduction [GO:0007602]; visual perception [GO:0007601] GO:0004930; GO:0005886; GO:0007601; GO:0007602; GO:0009881 42239 XM_044328557.1 318 202 0 211 13 NA NA NA NA NA NA 42240 XM_029355984.2 0 0 0 0 12 NA NA NA NA NA NA 42241 XM_044323937.1 54 48 33 76 133 Q91ZV3 2.09e-22 Discoidin, CUB and LCCL domain-containing protein 2 (Endothelial and smooth muscle cell-derived neuropilin-like protein) Mus musculus (Mouse) negative regulation of cell growth [GO:0030308]; wound healing [GO:0042060] GO:0005886; GO:0009986; GO:0030308; GO:0038023; GO:0042060 42242 XM_044319192.1 356 184 220 383 229 O62852 1.28e-94 Short transient receptor potential channel 5 (Rtrp5) (TrpC5) (Capacitative calcium entry channel 2) (CCE2) Oryctolagus cuniculus (Rabbit) neuron apoptotic process [GO:0051402]; phosphatidylserine exposure on apoptotic cell surface [GO:0070782] GO:0005262; GO:0005886; GO:0034704; GO:0051402; GO:0070679; GO:0070782 42243 XR_003823510.2 8 0 8 7 7 NA NA NA NA NA NA 42244 XM_029334316.2 66912 60074 32606 47957 44116 P08251 1.25e-23 Sodium/potassium-transporting ATPase subunit beta-1 (Sodium/potassium-dependent ATPase subunit beta-1) Gallus gallus (Chicken) cellular potassium ion homeostasis [GO:0030007]; cellular sodium ion homeostasis [GO:0006883]; potassium ion import across plasma membrane [GO:1990573]; sodium ion export across plasma membrane [GO:0036376] GO:0001671; GO:0005890; GO:0006883; GO:0030007; GO:0036376; GO:1990573 42245 XM_029345862.2 82 11 50 0 168 Q8UW76 7.15e-102 T-box transcription factor TBX20 (T-box protein 20) (cTbx20) Gallus gallus (Chicken) aortic valve morphogenesis [GO:0003180]; atrial septum morphogenesis [GO:0060413]; atrioventricular canal development [GO:0036302]; blood circulation [GO:0008015]; branching involved in blood vessel morphogenesis [GO:0001569]; cardiac chamber formation [GO:0003207]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac right ventricle morphogenesis [GO:0003215]; cell fate specification [GO:0001708]; cell migration involved in heart development [GO:0060973]; cell proliferation involved in heart valve development [GO:2000793]; dorsal/ventral pattern formation [GO:0009953]; embryonic heart tube elongation [GO:0036306]; endocardial cushion formation [GO:0003272]; foramen ovale closure [GO:0035922]; heart looping [GO:0001947]; mesenchymal cell development [GO:0014031]; motor neuron migration [GO:0097475]; muscle contraction [GO:0006936]; negative regulation of gene expression [GO:0010629]; negative regulation of SMAD protein complex assembly [GO:0010991]; negative regulation of transcription by RNA polymerase II [GO:0000122]; outflow tract septum morphogenesis [GO:0003148]; pericardium morphogenesis [GO:0003344]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell migration [GO:0030335]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of gene expression [GO:0010628]; pulmonary valve formation [GO:0003193]; pulmonary vein morphogenesis [GO:0060577]; regulation of transcription by RNA polymerase II [GO:0006357]; tricuspid valve development [GO:0003175]; vasculogenesis [GO:0001570]; visceral motor neuron differentiation [GO:0021524] GO:0000122; GO:0000978; GO:0000981; GO:0001228; GO:0001569; GO:0001570; GO:0001708; GO:0001947; GO:0003148; GO:0003175; GO:0003180; GO:0003193; GO:0003207; GO:0003215; GO:0003272; GO:0003344; GO:0005634; GO:0005737; GO:0006357; GO:0006936; GO:0008015; GO:0009953; GO:0010628; GO:0010629; GO:0010718; GO:0010991; GO:0014031; GO:0021524; GO:0030335; GO:0030513; GO:0035922; GO:0036302; GO:0036306; GO:0055008; GO:0060045; GO:0060413; GO:0060577; GO:0060973; GO:0061629; GO:0097475; GO:2000793 42246 XM_029339896.2 520 577 196 323 511 NA NA NA NA NA NA 42247 XM_044308214.1 159 241 179 113 95 NA NA NA NA NA NA 42248 XM_029343155.2 5221 5046 2916 3642 3248 NA NA NA NA NA NA 42249 XM_029356760.2 356 98 319 399 603 Q8NHP1 4.69e-92 Aflatoxin B1 aldehyde reductase member 4 (EC 1.-.-.-) (AFB1 aldehyde reductase 3) (AFB1-AR 3) (Aldoketoreductase 7-like) Homo sapiens (Human) NA GO:0004033; GO:0005737; GO:0005829; GO:0070062 42250 XM_044324989.1 0 0 0 124 0 NA NA NA NA NA NA 42251 XM_029358300.2 222 0 50 68 83 Q9QYS2 0 Metabotropic glutamate receptor 3 (mGluR3) Mus musculus (Mouse) G protein-coupled glutamate receptor signaling pathway [GO:0007216]; gene expression [GO:0010467]; modulation of chemical synaptic transmission [GO:0050804]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; regulation of sensory perception of pain [GO:0051930]; regulation of synaptic transmission, glutamatergic [GO:0051966]; sensory perception of pain [GO:0019233]; synaptic transmission, glutamatergic [GO:0035249] GO:0001640; GO:0001641; GO:0005246; GO:0005886; GO:0007216; GO:0010467; GO:0014069; GO:0019233; GO:0030424; GO:0035249; GO:0042734; GO:0043005; GO:0043197; GO:0045211; GO:0048786; GO:0050804; GO:0051930; GO:0051966; GO:0097110; GO:0097449; GO:0098978; GO:0099170 42252 XM_044320581.1 92 31 0 0 0 NA NA NA NA NA NA 42253 XM_029345037.2 15 30 29 50 40 NA NA NA NA NA NA 42254 XM_044315744.1 5 105 11 19 22 P10079 1.03e-78 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 42255 XM_044315744.1 5 105 11 19 22 P10079 5.08e-78 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 42256 XM_044315744.1 5 105 11 19 22 P10079 6.84e-76 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 42257 XM_044315744.1 5 105 11 19 22 P10079 2.95e-75 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 42258 XM_044315744.1 5 105 11 19 22 P10079 2.56e-74 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 42259 XM_044315744.1 5 105 11 19 22 P10079 4.02e-73 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 42260 XM_044315744.1 5 105 11 19 22 P10079 4.13e-73 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 42261 XM_044315744.1 5 105 11 19 22 P10079 4.17e-73 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 42262 XM_044315744.1 5 105 11 19 22 P10079 1.08e-72 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 42263 XM_044315744.1 5 105 11 19 22 P10079 1.7e-72 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 42264 XM_044315744.1 5 105 11 19 22 P10079 9.11e-70 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 42265 XM_044315744.1 5 105 11 19 22 P10079 2.39e-69 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 42266 XM_044315744.1 5 105 11 19 22 P10079 3.28e-68 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 42267 XM_044315744.1 5 105 11 19 22 P10079 2.26e-67 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 42268 XR_003826352.2 181 79 71 228 222 NA NA NA NA NA NA 42269 XM_029336595.2 2721 1333 2705 3525 1953 Q04336 0 Uncharacterized protein YMR196W Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) oligosaccharide metabolic process [GO:0009311] GO:0004573; GO:0005737; GO:0009311 42270 XM_044319167.1 167 34 17 0 0 O88917 1.29e-48 Adhesion G protein-coupled receptor L1 (Calcium-independent alpha-latrotoxin receptor 1) (CIRL-1) (Latrophilin-1) Rattus norvegicus (Rat) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; brain development [GO:0007420]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell surface receptor signaling pathway [GO:0007166]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synapse maturation [GO:0090129] GO:0004930; GO:0005886; GO:0007157; GO:0007166; GO:0007189; GO:0007420; GO:0014069; GO:0015643; GO:0016524; GO:0030246; GO:0030424; GO:0030426; GO:0035584; GO:0042734; GO:0043005; GO:0045202; GO:0050839; GO:0051965; GO:0090129; GO:0098978 42271 XM_044317976.1 161 125 0 75 202 Q7TQH0 4.4e-28 Ataxin-2-like protein Mus musculus (Mouse) mRNA metabolic process [GO:0016071]; stress granule assembly [GO:0034063] GO:0003723; GO:0005829; GO:0010494; GO:0016020; GO:0016071; GO:0016607; GO:0034063 42272 XR_006395332.1 62 12 48 15 67 NA NA NA NA NA NA 42273 XM_029333796.2 175 242 120 111 428 Q969Q6 0 Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma (Protein phosphatase subunit G5PR) (Rhabdomyosarcoma antigen MU-RMS-40.6A/6C) Homo sapiens (Human) activation of protein kinase activity [GO:0032147]; B cell homeostasis [GO:0001782]; cortical cytoskeleton organization [GO:0030865]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of B cell differentiation [GO:0045579]; regulation of antimicrobial humoral response [GO:0002759]; regulation of dephosphorylation [GO:0035303]; regulation of mitochondrial depolarization [GO:0051900]; spleen development [GO:0048536]; T cell homeostasis [GO:0043029] GO:0000226; GO:0001782; GO:0002759; GO:0005654; GO:0005794; GO:0005813; GO:0005829; GO:0030865; GO:0032147; GO:0035303; GO:0043029; GO:0045579; GO:0046872; GO:0048536; GO:0051900 42274 XM_029355644.2 1330 1107 744 1301 1285 Q26630 3.32e-144 33 kDa inner dynein arm light chain, axonemal (p33) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005930; GO:0030175; GO:0030286; GO:0045504 42275 XM_029350888.2 10387 10411 6931 10620 10476 NA NA NA NA NA NA 42276 XM_044328971.1 44 3 86 105 73 NA NA NA NA NA NA 42277 XM_044310768.1 1 0 0 8 27 NA NA NA NA NA NA 42278 XM_029357273.2 1456 901 405 400 671 Q16720 3.25e-113 Plasma membrane calcium-transporting ATPase 3 (PMCA3) (EC 7.2.2.10) (Plasma membrane calcium ATPase isoform 3) (Plasma membrane calcium pump isoform 3) Homo sapiens (Human) calcium ion export across plasma membrane [GO:1990034]; cellular calcium ion homeostasis [GO:0006874]; ion transmembrane transport [GO:0034220]; regulation of cardiac conduction [GO:1903779]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0005388; GO:0005516; GO:0005524; GO:0005886; GO:0006874; GO:0015085; GO:0016887; GO:0019829; GO:0030165; GO:0034220; GO:0042734; GO:0043231; GO:0046872; GO:0051480; GO:0098688; GO:0098978; GO:0098982; GO:1903561; GO:1903779; GO:1905056; GO:1990032; GO:1990034 42279 XM_029357273.2 1456 901 405 400 671 Q16720 5.46e-50 Plasma membrane calcium-transporting ATPase 3 (PMCA3) (EC 7.2.2.10) (Plasma membrane calcium ATPase isoform 3) (Plasma membrane calcium pump isoform 3) Homo sapiens (Human) calcium ion export across plasma membrane [GO:1990034]; cellular calcium ion homeostasis [GO:0006874]; ion transmembrane transport [GO:0034220]; regulation of cardiac conduction [GO:1903779]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0005388; GO:0005516; GO:0005524; GO:0005886; GO:0006874; GO:0015085; GO:0016887; GO:0019829; GO:0030165; GO:0034220; GO:0042734; GO:0043231; GO:0046872; GO:0051480; GO:0098688; GO:0098978; GO:0098982; GO:1903561; GO:1903779; GO:1905056; GO:1990032; GO:1990034 42280 XM_029357273.2 1456 901 405 400 671 Q16720 4.23e-32 Plasma membrane calcium-transporting ATPase 3 (PMCA3) (EC 7.2.2.10) (Plasma membrane calcium ATPase isoform 3) (Plasma membrane calcium pump isoform 3) Homo sapiens (Human) calcium ion export across plasma membrane [GO:1990034]; cellular calcium ion homeostasis [GO:0006874]; ion transmembrane transport [GO:0034220]; regulation of cardiac conduction [GO:1903779]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0005388; GO:0005516; GO:0005524; GO:0005886; GO:0006874; GO:0015085; GO:0016887; GO:0019829; GO:0030165; GO:0034220; GO:0042734; GO:0043231; GO:0046872; GO:0051480; GO:0098688; GO:0098978; GO:0098982; GO:1903561; GO:1903779; GO:1905056; GO:1990032; GO:1990034 42281 XM_029338521.2 1236 1231 864 967 643 Q91YT2 5.16e-52 E3 ubiquitin-protein ligase RNF185 (EC 2.3.2.27) (RING finger protein 185) Mus musculus (Mouse) autophagy [GO:0006914]; defense response to virus [GO:0051607]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; innate immune response [GO:0045087]; positive regulation of ERAD pathway [GO:1904294]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein autoubiquitination [GO:0051865]; protein K27-linked ubiquitination [GO:0044314]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0005741; GO:0005783; GO:0005789; GO:0006511; GO:0006914; GO:0030433; GO:0036503; GO:0043130; GO:0044314; GO:0044390; GO:0044877; GO:0045087; GO:0046872; GO:0051607; GO:0051865; GO:0060340; GO:0061630; GO:0071712; GO:1904294 42282 XM_044327372.1 14 0 0 0 0 NA NA NA NA NA NA 42283 XM_044316491.1 0 47 0 9 0 NA NA NA NA NA NA 42284 XM_044323930.1 89 62 147 104 223 Q7SZN0 1.87e-27 Venom prothrombin activator pseutarin-C non-catalytic subunit (PCNS) (vPA) (Venom coagulation factor Va-like protein) [Cleaved into: Pseutarin-C non-catalytic subunit heavy chain; Pseutarin-C non-catalytic subunit light chain] Pseudonaja textilis (Eastern brown snake) envenomation resulting in positive regulation of blood coagulation in another organism [GO:0044469]; positive regulation of blood coagulation in another organism [GO:0035807]; positive regulation of peptidase activity [GO:0010952] GO:0005507; GO:0005576; GO:0010952; GO:0016504; GO:0032991; GO:0035807; GO:0044469; GO:0090729 42285 XM_044324579.1 2 0 8 1 41 NA NA NA NA NA NA 42286 XM_044311673.1 38 14 80 17 122 NA NA NA NA NA NA 42287 XM_029340867.2 840 860 566 833 793 P59910 1.97e-137 DnaJ homolog subfamily B member 13 (Testis and spermatogenesis cell-related protein 6) (Testis spermatocyte apoptosis-related gene 6 protein) (Testis spermatogenesis apoptosis-related gene 3 protein) (Testis spermatogenesis apoptosis-related gene 6 protein) Homo sapiens (Human) axonemal central apparatus assembly [GO:1904158]; chaperone cofactor-dependent protein refolding [GO:0051085] GO:0005829; GO:0005930; GO:0031514; GO:0036126; GO:0051082; GO:0051085; GO:0051087; GO:0097224; GO:1904158 42288 XM_029351370.2 0 0 0 0 6 Q5F477 1.18e-64 Lipid droplet-associated hydrolase (EC 3.1.1.-) (Lipid droplet-associated serine hydrolase) Gallus gallus (Chicken) lipid storage [GO:0019915] GO:0004771; GO:0005783; GO:0005811; GO:0019915 42289 XM_044328199.1 1023 842 676 997 917 NA NA NA NA NA NA 42290 XM_029334090.2 4526 8348 8595 6868 4816 NA NA NA NA NA NA 42291 XM_044307085.1 51 41 0 33 0 P97363 0 Serine palmitoyltransferase 2 (EC 2.3.1.50) (Long chain base biosynthesis protein 2) (LCB 2) (Long chain base biosynthesis protein 2a) (LCB2a) (Serine-palmitoyl-CoA transferase 2) (SPT 2) Mus musculus (Mouse) adipose tissue development [GO:0060612]; ceramide biosynthetic process [GO:0046513]; lipophagy [GO:0061724]; positive regulation of lipophagy [GO:1904504]; sphinganine biosynthetic process [GO:0046511]; sphingolipid biosynthetic process [GO:0030148]; sphingomyelin biosynthetic process [GO:0006686]; sphingosine biosynthetic process [GO:0046512] GO:0004758; GO:0005739; GO:0005789; GO:0006686; GO:0017059; GO:0030148; GO:0030170; GO:0046511; GO:0046512; GO:0046513; GO:0060612; GO:0061724; GO:1904504 42292 XM_044317331.1 795 2819 329 255 190 NA NA NA NA NA NA 42293 XM_029335284.2 416 717 238 571 273 Q09694 2.57e-97 Saccharopine dehydrogenase [NAD(+), L-lysine-forming] (SDH) (EC 1.5.1.7) (Lysine--2-oxoglutarate reductase) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) lysine biosynthetic process [GO:0009085]; lysine biosynthetic process via aminoadipic acid [GO:0019878] GO:0004753; GO:0004754; GO:0005737; GO:0009085; GO:0019878 42294 XM_044309733.1 15 0 0 23 25 P10079 0 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 42295 XM_044309733.1 15 0 0 23 25 P10079 0 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 42296 XM_044309733.1 15 0 0 23 25 P10079 0 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 42297 XM_044309733.1 15 0 0 23 25 P10079 0 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 42298 XM_044309733.1 15 0 0 23 25 P10079 3.45e-109 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 42299 XM_029323567.2 27 30 34 58 40 NA NA NA NA NA NA 42300 XM_029338967.2 92 50 68 164 90 Q9GV41 9.04e-85 9,11-endoperoxide prostaglandin H2 reductase (EC 1.1.1.-) (Prostaglandin F2-alpha synthase) Trypanosoma brucei brucei D-arabinose catabolic process [GO:0019571]; prostaglandin biosynthetic process [GO:0001516] GO:0000166; GO:0001516; GO:0004033; GO:0005737; GO:0019571; GO:0036130; GO:0045290 42301 XM_044307159.1 0 0 0 0 29 Q91ZQ5 9.34e-99 Retinoid isomerohydrolase (EC 3.1.1.64) (All-trans-retinyl-palmitate hydrolase) (Lutein isomerase) (Meso-zeaxanthin isomerase) (EC 5.3.3.22) (Retinal pigment epithelium-specific 65 kDa protein) (Retinol isomerase) Mus musculus (Mouse) cellular response to electrical stimulus [GO:0071257]; circadian rhythm [GO:0007623]; detection of light stimulus involved in visual perception [GO:0050908]; insulin receptor signaling pathway [GO:0008286]; neural retina development [GO:0003407]; regulation of gene expression [GO:0010468]; retina development in camera-type eye [GO:0060041]; retina homeostasis [GO:0001895]; retina morphogenesis in camera-type eye [GO:0060042]; retinal metabolic process [GO:0042574]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; visual perception [GO:0007601]; zeaxanthin biosynthetic process [GO:1901827] GO:0001523; GO:0001786; GO:0001895; GO:0003407; GO:0005634; GO:0005737; GO:0005789; GO:0005886; GO:0007601; GO:0007623; GO:0008286; GO:0010468; GO:0016020; GO:0016702; GO:0016853; GO:0031210; GO:0042572; GO:0042574; GO:0044297; GO:0046872; GO:0050251; GO:0050908; GO:0052884; GO:0052885; GO:0060041; GO:0060042; GO:0071257; GO:1901612; GO:1901827 42302 XM_029357653.2 235 221 123 266 441 P48733 6.2e-29 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Bos taurus (Bovine) antibacterial innate immune response [GO:0140367]; defense response to Gram-negative bacterium [GO:0050829] GO:0000922; GO:0005201; GO:0005509; GO:0005576; GO:0005929; GO:0016020; GO:0016323; GO:0016324; GO:0031012; GO:0050829; GO:0060170; GO:0140367 42303 XM_044307042.1 211 82 267 99 408 Q7RTR2 5.24e-75 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 42304 XM_044307042.1 211 82 267 99 408 Q7RTR2 2.19e-73 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 42305 XM_044307042.1 211 82 267 99 408 Q7RTR2 1.26e-68 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 42306 XM_044307042.1 211 82 267 99 408 Q7RTR2 3.5e-68 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 42307 XM_044307042.1 211 82 267 99 408 Q7RTR2 1e-62 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 42308 XM_044307042.1 211 82 267 99 408 Q7RTR2 8.48e-62 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 42309 XM_044315295.1 0 0 0 0 21 NA NA NA NA NA NA 42310 XR_006393436.1 0 0 0 6 216 Q924C1 1.31e-54 Exportin-5 (Exp5) (Ran-binding protein 21) Mus musculus (Mouse) positive regulation of post-transcriptional gene silencing by RNA [GO:1900370]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; RNA export from nucleus [GO:0006405] GO:0000049; GO:0003723; GO:0003729; GO:0005049; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006405; GO:0006611; GO:0016442; GO:0031267; GO:0035281; GO:0042565; GO:0070883; GO:1900370; GO:1905172 42311 XM_044314190.1 9 6 18 8 7 NA NA NA NA NA NA 42312 XM_029331554.2 1932 1795 1491 1481 1460 Q9H477 8.23e-109 Ribokinase (RK) (EC 2.7.1.15) Homo sapiens (Human) D-ribose catabolic process [GO:0019303]; pentose-phosphate shunt [GO:0006098] GO:0004747; GO:0005524; GO:0005634; GO:0005829; GO:0006098; GO:0019303; GO:0042802; GO:0046872 42313 XM_029353977.2 17 0 25 64 27 NA NA NA NA NA NA 42314 XM_029325555.2 11 4 13 5 45 Q9VGI8 3.86e-40 RecQ-like DNA helicase Blm (EC 3.6.4.12) (Bloom syndrome helicase ortholog) (Bloom syndrome protein homolog) (Dmblm) (Mutagen-sensitive protein 309) (RecQ helicase homolog) Drosophila melanogaster (Fruit fly) cellular response to DNA damage stimulus [GO:0006974]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA synthesis involved in DNA repair [GO:0000731]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair [GO:0006302]; double-strand break repair involved in meiotic recombination [GO:1990918]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; double-strand break repair via synthesis-dependent strand annealing [GO:0045003]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; reciprocal meiotic recombination [GO:0007131]; strand displacement [GO:0000732] GO:0000403; GO:0000724; GO:0000731; GO:0000732; GO:0003678; GO:0005524; GO:0005634; GO:0005694; GO:0005737; GO:0006268; GO:0006281; GO:0006302; GO:0006303; GO:0006310; GO:0006974; GO:0007131; GO:0009378; GO:0016887; GO:0032508; GO:0043138; GO:0045003; GO:0046872; GO:1901291; GO:1990814; GO:1990918 42315 XM_044308697.1 0 111 52 0 0 NA NA NA NA NA NA 42316 XM_029333784.2 102 32 26 72 92 Q8BH16 5.22e-24 F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2) Mus musculus (Mouse) modulation by host of viral RNA genome replication [GO:0044830]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; protein monoubiquitination [GO:0006513]; protein ubiquitination [GO:0016567]; regulation of autophagy [GO:0010506]; regulation of inflammatory response [GO:0050727]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0005516; GO:0006511; GO:0006513; GO:0010506; GO:0014066; GO:0016020; GO:0016567; GO:0019005; GO:0019903; GO:0031146; GO:0036312; GO:0044830; GO:0050727; GO:1900226; GO:1990756 42317 XM_029344783.2 110 135 93 134 108 P58912 3.92e-70 DELTA-alicitoxin-Pse2b (DELTA-ALTX-Pse2b) (Toxin PsTX-60B) (PTX60B) Phyllodiscus semoni (Night anemone) hemolysis in another organism [GO:0044179] GO:0005576; GO:0042151; GO:0044179; GO:0090729 42318 XM_029351547.2 360 179 281 485 380 Q8R2K4 5.52e-97 TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (TAF6L) (PCAF-associated factor 65-alpha) (PAF65-alpha) Mus musculus (Mouse) histone acetylation [GO:0016573]; histone H3 acetylation [GO:0043966]; monoubiquitinated histone deubiquitination [GO:0035521]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA repair [GO:0006282]; regulation of DNA-templated transcription [GO:0006355]; regulation of RNA splicing [GO:0043484]; regulation of somatic stem cell population maintenance [GO:1904672]; RNA polymerase II preinitiation complex assembly [GO:0051123] GO:0000124; GO:0003713; GO:0005634; GO:0005654; GO:0005669; GO:0006282; GO:0006355; GO:0016251; GO:0016573; GO:0035521; GO:0035522; GO:0043484; GO:0043966; GO:0045893; GO:0046695; GO:0046982; GO:0051123; GO:1904672 42319 XM_029347891.2 7601 11018 10623 12861 9000 Q309Z6 4.9e-80 Hypoxia-inducible factor 1-alpha (HIF-1-alpha) (HIF1-alpha) Eospalax fontanierii baileyi (Plateau zokor) (Eospalax baileyi) axonal transport of mitochondrion [GO:0019896]; cellular glucose homeostasis [GO:0001678]; cellular response to hypoxia [GO:0071456]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; regulation of gene expression [GO:0010468]; regulation of glycolytic process [GO:0006110]; regulation of protein neddylation [GO:2000434]; response to hypoxia [GO:0001666]; response to reactive oxygen species [GO:0000302] GO:0000302; GO:0001223; GO:0001666; GO:0001678; GO:0003700; GO:0005634; GO:0005829; GO:0006110; GO:0010468; GO:0016607; GO:0019896; GO:0043565; GO:0045893; GO:0045944; GO:0046982; GO:0061419; GO:0071456; GO:1900017; GO:1904115; GO:2000434 42320 XM_029343319.2 523 1212 2380 1037 1960 O97562 4.93e-113 Dicarboxylate carrier SLC25A8 (Mitochondrial uncoupling protein 2) (UCP 2) (Solute carrier family 25 member 8) Sus scrofa (Pig) adaptive thermogenesis [GO:1990845]; C4-dicarboxylate transport [GO:0015740]; cellular response to glucose stimulus [GO:0071333]; glutamine metabolic process [GO:0006541]; glycolytic process [GO:0006096]; macrophage differentiation [GO:0030225]; mitochondrial fission [GO:0000266]; mitochondrial transmembrane transport [GO:1990542]; mitochondrial transport [GO:0006839]; reactive oxygen species metabolic process [GO:0072593]; response to cold [GO:0009409] GO:0000266; GO:0005743; GO:0006096; GO:0006541; GO:0006839; GO:0008271; GO:0009409; GO:0015078; GO:0015131; GO:0015140; GO:0015183; GO:0015297; GO:0015740; GO:0017077; GO:0022857; GO:0030225; GO:0042803; GO:0071333; GO:0072593; GO:0140787; GO:1990542; GO:1990845 42321 XM_044320693.1 29 20 5 24 24 NA NA NA NA NA NA 42322 XM_044310395.1 12 2 23 9 23 NA NA NA NA NA NA 42323 XM_029334805.2 340 340 282 405 571 O75691 0 Small subunit processome component 20 homolog (Down-regulated in metastasis protein) (Novel nucleolar protein 73) (NNP73) (Protein Key-1A6) Homo sapiens (Human) endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000480]; endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000447]; endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000472]; negative regulation of cell population proliferation [GO:0008285]; rRNA processing [GO:0006364] GO:0000447; GO:0000472; GO:0000480; GO:0003723; GO:0005654; GO:0005730; GO:0005737; GO:0005886; GO:0006364; GO:0008285; GO:0030686; GO:0030688; GO:0032040 42324 XM_044310074.1 30 87 14 10 10 P0CT40 2.11e-83 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 42325 XM_029325848.2 2240 1753 1398 1762 1082 Q7TPQ9 9.17e-26 Arrestin domain-containing protein 3 Mus musculus (Mouse) fat pad development [GO:0060613]; heat generation [GO:0031649]; negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071878]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of heat generation [GO:0031651]; negative regulation of locomotion involved in locomotory behavior [GO:0090327]; positive regulation of hippo signaling [GO:0035332]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein transport [GO:0015031]; skin development [GO:0043588]; temperature homeostasis [GO:0001659] GO:0001659; GO:0005737; GO:0005764; GO:0005768; GO:0005769; GO:0005886; GO:0015031; GO:0031649; GO:0031651; GO:0031699; GO:0035332; GO:0043588; GO:0051443; GO:0060613; GO:0071878; GO:0090327; GO:0120163 42326 XM_044317406.1 2 0 12 1 60 Q6NUT3 2.05e-21 Major facilitator superfamily domain-containing protein 12 Homo sapiens (Human) carbohydrate transport [GO:0008643]; cysteine transmembrane transport [GO:1903712]; melanin biosynthetic process [GO:0042438]; negative regulation of melanin biosynthetic process [GO:0048022]; organic substance transport [GO:0071702]; pigment metabolic process involved in pigmentation [GO:0043474]; regulation of melanin biosynthetic process [GO:0048021] GO:0005764; GO:0005765; GO:0005770; GO:0005886; GO:0008643; GO:0015293; GO:0033162; GO:0033229; GO:0042438; GO:0042470; GO:0043474; GO:0048021; GO:0048022; GO:0071702; GO:1903712 42327 XM_029344328.2 427 185 253 399 555 Q9H4W6 0 Transcription factor COE3 (Early B-cell factor 3) (EBF-3) (Olf-1/EBF-like 2) (O/E-2) (OE-2) Homo sapiens (Human) positive regulation of DNA-templated transcription [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000785; GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0045893; GO:0046872 42328 XM_044324860.1 61 32 15 24 53 Q94K49 1e-36 Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1 (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) epigenetic regulation of gene expression [GO:0040029] GO:0003682; GO:0004518; GO:0005634; GO:0035098; GO:0035102; GO:0040029; GO:0046872 42329 XM_029324551.2 281 154 151 257 243 NA NA NA NA NA NA 42330 XM_044310399.1 687 15 763 8 1027 NA NA NA NA NA NA 42331 XM_029357478.2 0 92 0 0 0 NA NA NA NA NA NA 42332 XM_029354756.2 129 50 607 1837 977 Q9EQC4 1.15e-63 Elongation of very long chain fatty acids protein 4 (EC 2.3.1.199) (3-keto acyl-CoA synthase Elovl4) (ELOVL fatty acid elongase 4) (ELOVL FA elongase 4) (Very long chain 3-ketoacyl-CoA synthase 4) (Very long chain 3-oxoacyl-CoA synthase 4) Mus musculus (Mouse) fatty acid elongation, monounsaturated fatty acid [GO:0034625]; fatty acid elongation, polyunsaturated fatty acid [GO:0034626]; fatty acid elongation, saturated fatty acid [GO:0019367]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; sphingolipid biosynthetic process [GO:0030148]; unsaturated fatty acid biosynthetic process [GO:0006636]; very long-chain fatty acid biosynthetic process [GO:0042761] GO:0005783; GO:0005789; GO:0006636; GO:0009922; GO:0019367; GO:0030148; GO:0034625; GO:0034626; GO:0035338; GO:0042761; GO:0102756 42333 XM_029347934.2 0 202 101 139 39 Q99K85 9.37e-159 Phosphoserine aminotransferase (PSAT) (EC 2.6.1.52) (Endometrial progesterone-induced protein) (EPIP) (Phosphohydroxythreonine aminotransferase) Mus musculus (Mouse) L-serine biosynthetic process [GO:0006564] GO:0004648; GO:0005737; GO:0005829; GO:0006564; GO:0030170; GO:0042802 42334 XR_006393106.1 141 39 116 46 30 NA NA NA NA NA NA 42335 XM_044328152.1 11 13 27 22 15 NA NA NA NA NA NA 42336 XM_044310908.1 263 36 167 739 626 NA NA NA NA NA NA 42337 XM_044308372.1 921 947 378 888 474 Q08D86 3.79e-176 Putative glycerol kinase 5 (GK 5) (Glycerokinase 5) (EC 2.7.1.30) (ATP:glycerol 3-phosphotransferase 5) Bos taurus (Bovine) glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate biosynthetic process [GO:0046167]; phosphorylation [GO:0016310]; triglyceride metabolic process [GO:0006641] GO:0004370; GO:0005524; GO:0005739; GO:0006071; GO:0006641; GO:0016310; GO:0019563; GO:0046167 42338 XM_044319818.1 0 71 0 4 51 O46504 6.72e-170 Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial (PDPr) Bos taurus (Bovine) NA GO:0005759; GO:0016491 42339 XR_006393726.1 30 8 41 95 108 NA NA NA NA NA NA 42340 XM_029332355.2 0 0 59 0 0 Q5XJN2 4.76e-49 Gamma-interferon-inducible lysosomal thiol reductase (EC 1.8.-.-) (Gamma-interferon-inducible protein IP-30) Danio rerio (Zebrafish) (Brachydanio rerio) immune system process [GO:0002376] GO:0002376; GO:0005576; GO:0005764; GO:0016491; GO:0016667; GO:0016671; GO:0047134 42341 XM_044328279.1 13 44 0 0 0 NA NA NA NA NA NA 42342 XM_044317008.1 749 370 367 735 862 P11533 0 Dystrophin Gallus gallus (Chicken) actin filament bundle assembly [GO:0051017]; actin filament network formation [GO:0051639] GO:0005737; GO:0005884; GO:0008270; GO:0032432; GO:0042383; GO:0045211; GO:0051015; GO:0051017; GO:0051639; GO:0120025 42343 XM_044317008.1 749 370 367 735 862 P11533 2.39e-49 Dystrophin Gallus gallus (Chicken) actin filament bundle assembly [GO:0051017]; actin filament network formation [GO:0051639] GO:0005737; GO:0005884; GO:0008270; GO:0032432; GO:0042383; GO:0045211; GO:0051015; GO:0051017; GO:0051639; GO:0120025 42344 XR_006392682.1 6 1 4 12 7 NA NA NA NA NA NA 42345 XM_029344653.2 2099 1916 1376 2028 2216 O75400 1.74e-101 Pre-mRNA-processing factor 40 homolog A (Fas ligand-associated factor 1) (Formin-binding protein 11) (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein 10) (HIP-10) (Huntingtin-interacting protein A) (Renal carcinoma antigen NY-REN-6) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; regulation of cell shape [GO:0008360]; regulation of cytokinesis [GO:0032465] GO:0000398; GO:0003723; GO:0005654; GO:0005685; GO:0007010; GO:0007049; GO:0008360; GO:0016020; GO:0016363; GO:0016477; GO:0016607; GO:0032465; GO:0045292; GO:0051301; GO:0071004 42346 XM_029344653.2 2099 1916 1376 2028 2216 O75400 7.68e-23 Pre-mRNA-processing factor 40 homolog A (Fas ligand-associated factor 1) (Formin-binding protein 11) (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein 10) (HIP-10) (Huntingtin-interacting protein A) (Renal carcinoma antigen NY-REN-6) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; regulation of cell shape [GO:0008360]; regulation of cytokinesis [GO:0032465] GO:0000398; GO:0003723; GO:0005654; GO:0005685; GO:0007010; GO:0007049; GO:0008360; GO:0016020; GO:0016363; GO:0016477; GO:0016607; GO:0032465; GO:0045292; GO:0051301; GO:0071004 42347 XM_029334462.2 164 0 218 295 315 P54366 5.79e-32 Homeobox protein goosecoid Drosophila melanogaster (Fruit fly) negative regulation of DNA-templated transcription [GO:0045892]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000977; GO:0000981; GO:0001227; GO:0005634; GO:0006357; GO:0042803; GO:0045892; GO:0046982 42348 XM_029349684.2 12 2 11 8 29 P34992 3.19e-21 Neuropeptide Y receptor type 1 (NPY1-R) Xenopus laevis (African clawed frog) NA GO:0004983; GO:0005886 42349 XM_029344180.2 330 32 178 70 368 NA NA NA NA NA NA 42350 XM_029351065.2 581 233 285 498 526 Q07598 0 Sterol carrier protein 2 (SCP-2) (Acetyl-CoA C-myristoyltransferase) (EC 2.3.1.155) (Non-specific lipid-transfer protein) (NSL-TP) (Propanoyl-CoA C-acyltransferase) (EC 2.3.1.176) (SCP-2/3-oxoacyl-CoA thiolase) (SCP-2/thiolase) (EC 2.3.1.16) (SCP-chi) (SCPX) (Sterol carrier protein X) (SCP-X) Gallus gallus (Chicken) bile acid metabolic process [GO:0008206]; fatty acid beta-oxidation [GO:0006635]; lipid transport [GO:0006869]; positive regulation of intracellular cholesterol transport [GO:0032385] GO:0003988; GO:0005737; GO:0005739; GO:0005777; GO:0005782; GO:0005783; GO:0006635; GO:0006869; GO:0008206; GO:0008289; GO:0032385; GO:0033814; GO:0050632; GO:0050633; GO:0120019; GO:0120020 42351 XM_029345216.2 134 48 76 98 172 Q92685 1.02e-143 Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase (EC 2.4.1.258) (Asparagine-linked glycosylation protein 3 homolog) (Dol-P-Man-dependent alpha(1-3)-mannosyltransferase) (Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase) (Dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase) (Not56-like protein) Homo sapiens (Human) dolichol-linked oligosaccharide biosynthetic process [GO:0006488]; protein glycosylation [GO:0006486] GO:0000033; GO:0005783; GO:0005789; GO:0006486; GO:0006488; GO:0052925 42352 XR_006396177.1 88 35 30 34 150 NA NA NA NA NA NA 42353 XM_029356808.2 584 8 6 5 799 NA NA NA NA NA NA 42354 XM_029343924.2 105 0 66 0 117 Q3TZX8 1.29e-72 Polynucleotide 5'-hydroxyl-kinase NOL9 (EC 2.7.1.-) (Nucleolar protein 9) Mus musculus (Mouse) cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000448]; maturation of 5.8S rRNA [GO:0000460]; phosphorylation [GO:0016310]; RNA processing [GO:0006396] GO:0000448; GO:0000460; GO:0003723; GO:0005524; GO:0005634; GO:0005730; GO:0006396; GO:0016310; GO:0045111; GO:0051731 42355 XM_029350661.2 310 339 272 317 169 NA NA NA NA NA NA 42356 XM_029355177.2 2993 2793 2210 3391 1522 P59055 4.17e-30 Cysteine/serine-rich nuclear protein 3 (CSRNP-3) (Protein FAM130A2) (TGF-beta-induced apoptosis protein 2) (TAIP-2) Mus musculus (Mouse) apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000981; GO:0001228; GO:0003700; GO:0005634; GO:0006357; GO:0006915; GO:0043065; GO:0043565; GO:0045944 42357 XM_029333756.2 2635 1489 1308 2234 1894 Q07889 0 Son of sevenless homolog 1 (SOS-1) Homo sapiens (Human) axon guidance [GO:0007411]; B cell homeostasis [GO:0001782]; B cell receptor signaling pathway [GO:0050853]; blood vessel morphogenesis [GO:0048514]; cardiac atrium morphogenesis [GO:0003209]; cytokine-mediated signaling pathway [GO:0019221]; epidermal growth factor receptor signaling pathway [GO:0007173]; eyelid development in camera-type eye [GO:0061029]; Fc-epsilon receptor signaling pathway [GO:0038095]; fibroblast growth factor receptor signaling pathway [GO:0008543]; hair follicle development [GO:0001942]; heart trabecula morphogenesis [GO:0061384]; insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009]; leukocyte migration [GO:0050900]; midbrain morphogenesis [GO:1904693]; multicellular organism growth [GO:0035264]; neurotrophin TRK receptor signaling pathway [GO:0048011]; pericardium morphogenesis [GO:0003344]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of GTPase activity [GO:0043547]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; Ras protein signal transduction [GO:0007265]; regulation of cell population proliferation [GO:0042127]; regulation of MAP kinase activity [GO:0043405]; regulation of pro-B cell differentiation [GO:2000973]; regulation of T cell differentiation in thymus [GO:0033081]; regulation of T cell proliferation [GO:0042129]; regulation of transcription by RNA polymerase II [GO:0006357]; roof of mouth development [GO:0060021]; signal transduction [GO:0007165]; vitellogenesis [GO:0007296] GO:0001782; GO:0001942; GO:0003209; GO:0003344; GO:0005085; GO:0005096; GO:0005737; GO:0005829; GO:0005886; GO:0006357; GO:0007165; GO:0007173; GO:0007265; GO:0007296; GO:0007411; GO:0008286; GO:0008543; GO:0014069; GO:0017124; GO:0019221; GO:0033081; GO:0035264; GO:0038095; GO:0042127; GO:0042129; GO:0043025; GO:0043405; GO:0043539; GO:0043547; GO:0045742; GO:0046982; GO:0048009; GO:0048011; GO:0048514; GO:0050853; GO:0050900; GO:0051057; GO:0060021; GO:0061029; GO:0061384; GO:1904693; GO:1905360; GO:2000973 42358 XM_029348446.2 477 111 196 279 133 Q8IYS1 1.27e-111 Xaa-Arg dipeptidase (EC 3.4.13.4) (Beta-Ala-Lys dipeptidase) Homo sapiens (Human) proteolysis [GO:0006508]; regulation of protein metabolic process [GO:0051246] GO:0004180; GO:0005654; GO:0006508; GO:0016805; GO:0042802; GO:0051246 42359 XM_044311214.1 75 0 63 61 109 P46023 1.37e-93 G-protein coupled receptor GRL101 Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004930; GO:0005886 42360 XM_044312014.1 340 65 456 66 1456 NA NA NA NA NA NA 42361 XM_044315692.1 0 0 0 10 0 NA NA NA NA NA NA 42362 XR_006398082.1 41 7 17 29 24 NA NA NA NA NA NA 42363 XM_044317398.1 30 4 6 3 28 NA NA NA NA NA NA 42364 XM_029356131.2 0 0 0 0 44 Q9VCA2 1.1e-59 Organic cation transporter protein Drosophila melanogaster (Fruit fly) apoptotic process [GO:0006915]; ion transport [GO:0006811] GO:0006811; GO:0006915; GO:0016020; GO:0022857 42365 XM_044321739.1 91 35 65 0 79 NA NA NA NA NA NA 42366 XM_029323836.2 55 0 41 171 13 Q27319 0 Gelsolin, cytoplasmic (Actin-depolymerizing factor) (ADF) Homarus americanus (American lobster) actin filament capping [GO:0051693] GO:0005737; GO:0005856; GO:0046872; GO:0051015; GO:0051693 42367 XM_044320948.1 986 721 485 660 1069 Q700K0 6.93e-103 SCO-spondin Rattus norvegicus (Rat) cell adhesion [GO:0007155] GO:0005615; GO:0005737; GO:0007155; GO:0031012 42368 XM_044320948.1 986 721 485 660 1069 Q700K0 3.93e-84 SCO-spondin Rattus norvegicus (Rat) cell adhesion [GO:0007155] GO:0005615; GO:0005737; GO:0007155; GO:0031012 42369 XM_044320948.1 986 721 485 660 1069 Q700K0 7.85e-68 SCO-spondin Rattus norvegicus (Rat) cell adhesion [GO:0007155] GO:0005615; GO:0005737; GO:0007155; GO:0031012 42370 XM_044320948.1 986 721 485 660 1069 Q700K0 6.8e-60 SCO-spondin Rattus norvegicus (Rat) cell adhesion [GO:0007155] GO:0005615; GO:0005737; GO:0007155; GO:0031012 42371 XM_044320948.1 986 721 485 660 1069 Q700K0 5.11e-57 SCO-spondin Rattus norvegicus (Rat) cell adhesion [GO:0007155] GO:0005615; GO:0005737; GO:0007155; GO:0031012 42372 XM_044320948.1 986 721 485 660 1069 Q700K0 1.74e-41 SCO-spondin Rattus norvegicus (Rat) cell adhesion [GO:0007155] GO:0005615; GO:0005737; GO:0007155; GO:0031012 42373 XM_044320948.1 986 721 485 660 1069 Q700K0 3.59e-40 SCO-spondin Rattus norvegicus (Rat) cell adhesion [GO:0007155] GO:0005615; GO:0005737; GO:0007155; GO:0031012 42374 XM_044320948.1 986 721 485 660 1069 Q700K0 7.37e-39 SCO-spondin Rattus norvegicus (Rat) cell adhesion [GO:0007155] GO:0005615; GO:0005737; GO:0007155; GO:0031012 42375 XM_029335968.2 92 36 171 65 327 Q8L7C8 2.05e-84 Protein REDUCED WALL ACETYLATION 1 (EC 2.3.1.-) Arabidopsis thaliana (Mouse-ear cress) carbohydrate metabolic process [GO:0005975]; plant-type secondary cell wall biogenesis [GO:0009834]; xylan acetylation [GO:1990937]; xylan biosynthetic process [GO:0045492]; xylan metabolic process [GO:0045491]; xyloglucan metabolic process [GO:0010411] GO:0000139; GO:0005794; GO:0005975; GO:0009834; GO:0010411; GO:0016407; GO:0016491; GO:0045491; GO:0045492; GO:1990937 42376 XM_044313882.1 7 0 13 25 12 NA NA NA NA NA NA 42377 XM_044324883.1 55 0 29 28 79 Q70AG8 1.53e-22 Alpha-(1,3)-fucosyltransferase 11 (EC 2.4.1.-) (Fucosyltransferase XI) (Fuc-TXI) (FucT-XI) (Galactoside 3-L-fucosyltransferase 11) (Fucosyltransferase 11) Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0032580; GO:0046920 42378 XR_006396370.1 0 0 0 17 0 NA NA NA NA NA NA 42379 XR_006396780.1 2234 28632 32468 27285 29762 NA NA NA NA NA NA 42380 XM_044328284.1 154 304 234 40 423 NA NA NA NA NA NA 42381 XM_029335638.2 192 38 95 18 20 Q8BKD6 3.34e-64 E3 ubiquitin-protein ligase RNF144B (EC 2.3.2.31) (IBR domain-containing protein 2) (RING finger protein 144B) Mus musculus (Mouse) apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000151; GO:0000209; GO:0004842; GO:0005737; GO:0006511; GO:0006915; GO:0031624; GO:0031966; GO:0032436; GO:0043066; GO:0046872; GO:0061630 42382 XM_029344912.2 7 12 8 0 11 NA NA NA NA NA NA 42383 XM_044324397.1 167 139 8 70 202 Q9VBW3 3.18e-76 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 42384 XM_029342012.2 133 57 27 35 73 Q6AZB8 4.91e-57 Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0004518; GO:0005634; GO:0005737; GO:0046872 42385 XM_029340923.2 972 789 814 531 925 Q9D7M8 1.18e-65 DNA-directed RNA polymerase II subunit RPB4 (RNA polymerase II subunit B4) (DNA-directed RNA polymerase II subunit D) Mus musculus (Mouse) mRNA export from nucleus in response to heat stress [GO:0031990]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; positive regulation of translational initiation [GO:0045948]; recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex [GO:0034402]; transcription by RNA polymerase II [GO:0006366]; transcription initiation at RNA polymerase II promoter [GO:0006367] GO:0000166; GO:0000288; GO:0000932; GO:0005634; GO:0005654; GO:0005665; GO:0005829; GO:0006366; GO:0006367; GO:0016607; GO:0031369; GO:0031990; GO:0034402; GO:0045948 42386 XM_044325699.1 18 12 3 13 33 NA NA NA NA NA NA 42387 XM_044311723.1 0 0 11 1 10 NA NA NA NA NA NA 42388 XR_006392262.1 143 46 110 73 120 NA NA NA NA NA NA 42389 XM_029342024.2 2879 2736 1683 2586 2410 Q9UL25 7.78e-94 Ras-related protein Rab-21 Homo sapiens (Human) anterograde axonal transport [GO:0008089]; intracellular protein transport [GO:0006886]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of receptor-mediated endocytosis [GO:0048260]; protein stabilization [GO:0050821]; Rab protein signal transduction [GO:0032482]; regulation of axon extension [GO:0030516]; regulation of exocytosis [GO:0017157] GO:0000139; GO:0003924; GO:0005525; GO:0005768; GO:0005769; GO:0005789; GO:0005802; GO:0005829; GO:0005925; GO:0006886; GO:0008089; GO:0009898; GO:0012505; GO:0012506; GO:0017157; GO:0019003; GO:0030516; GO:0031901; GO:0032154; GO:0032482; GO:0032580; GO:0045202; GO:0048260; GO:0050775; GO:0050821; GO:0070062; GO:0098559; GO:1904115; GO:2000643 42390 XM_029323754.2 2 3 2 0 18 NA NA NA NA NA NA 42391 XM_044320377.1 2271 321 329 697 189 Q14517 0 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 42392 XM_044320377.1 2271 321 329 697 189 Q14517 6.6e-55 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 42393 XM_044320377.1 2271 321 329 697 189 Q14517 1.09e-34 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 42394 XM_029329302.2 561 578 450 533 523 NA NA NA NA NA NA 42395 XM_044319411.1 0 0 0 0 37 NA NA NA NA NA NA 42396 XM_029341403.2 180 201 152 164 280 Q8TBF8 2.43e-49 Protein FAM81A Homo sapiens (Human) NA GO:0098978; GO:0099092 42397 XM_044315929.1 32 6 55 3 150 Q7ZTV5 8.05e-22 Follicle-stimulating hormone receptor (FSH-R) (Follitropin receptor) Cairina moschata (Muscovy duck) cellular response to follicle-stimulating hormone stimulus [GO:0071372]; follicle-stimulating hormone signaling pathway [GO:0042699]; G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; regulation of protein kinase A signaling [GO:0010738] GO:0004930; GO:0004963; GO:0005886; GO:0007186; GO:0010738; GO:0014068; GO:0016020; GO:0042699; GO:0043235; GO:0070374; GO:0071372 42398 XM_029341127.2 194 81 0 198 1 I6V1W0 2.28e-93 Protein brambleberry Danio rerio (Zebrafish) (Brachydanio rerio) karyomere membrane fusion [GO:0061472]; pronuclear fusion [GO:0007344] GO:0007344; GO:0031965; GO:0061472 42399 XM_029357235.2 9 11 0 13 32 Q9VH19 8.64e-173 Leishmanolysin-like peptidase (EC 3.4.24.-) (Invadolysin) Drosophila melanogaster (Fruit fly) brain development [GO:0007420]; cell adhesion [GO:0007155]; cell division [GO:0051301]; centrosome duplication [GO:0051298]; chromatin remodeling [GO:0006338]; electron transport chain [GO:0022900]; germ cell migration [GO:0008354]; gonad development [GO:0008406]; imaginal disc development [GO:0007444]; lipid storage [GO:0019915]; mitotic centrosome separation [GO:0007100]; mitotic chromosome condensation [GO:0007076]; mitotic spindle organization [GO:0007052]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; proteolysis [GO:0006508]; regulation of choline O-acetyltransferase activity [GO:1902769] GO:0004222; GO:0005737; GO:0006338; GO:0006508; GO:0007052; GO:0007076; GO:0007100; GO:0007155; GO:0007420; GO:0007444; GO:0008233; GO:0008354; GO:0008406; GO:0016020; GO:0019915; GO:0022900; GO:0045842; GO:0046872; GO:0051298; GO:0051301; GO:1902769 42400 XM_044328800.1 0 0 0 2 6 NA NA NA NA NA NA 42401 XM_029334046.2 245 262 275 643 377 A0JPQ7 8e-27 Uncharacterized protein C19orf47 homolog Rattus norvegicus (Rat) NA GO:0005634 42402 XM_044318025.1 4 4 11 17 14 NA NA NA NA NA NA 42403 XM_044328048.1 486 288 198 884 414 Q7Z442 1.12e-76 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Homo sapiens (Human) detection of mechanical stimulus [GO:0050982] GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 42404 XM_044328048.1 486 288 198 884 414 Q7Z442 3.05e-68 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Homo sapiens (Human) detection of mechanical stimulus [GO:0050982] GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 42405 XM_029358358.2 30 194 28 0 111 Q3KP44 1.64e-63 Ankyrin repeat domain-containing protein 55 Homo sapiens (Human) NA NA 42406 XM_044311908.1 1 3 0 4 7 NA NA NA NA NA NA 42407 XR_006393680.1 11 21 10 0 0 NA NA NA NA NA NA 42408 XM_044311110.1 14 4 0 6 0 P04323 4.25e-59 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 42409 XM_029351955.2 669 103 396 597 412 NA NA NA NA NA NA 42410 XR_003826129.2 243 142 108 184 217 NA NA NA NA NA NA 42411 XM_044318828.1 1 137 1011 143 9 Q5R9T9 1.98e-47 Guanylate-binding protein 6 (EC 3.6.5.-) (GTP-binding protein 6) (GBP-6) (Guanine nucleotide-binding protein 6) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cellular response to type II interferon [GO:0071346]; defense response to bacterium [GO:0042742]; immune response [GO:0006955] GO:0003924; GO:0005525; GO:0006955; GO:0031410; GO:0042742; GO:0071346 42412 XM_029346133.2 0 75 128 0 61 Q5EAC5 7.71e-68 Zinc finger protein 410 Bos taurus (Bovine) regulation of transcription by RNA polymerase II [GO:0006357] GO:0003677; GO:0003712; GO:0005634; GO:0005694; GO:0006357; GO:0046872 42413 XM_029346133.2 0 75 128 0 61 Q5EAC5 8.55e-28 Zinc finger protein 410 Bos taurus (Bovine) regulation of transcription by RNA polymerase II [GO:0006357] GO:0003677; GO:0003712; GO:0005634; GO:0005694; GO:0006357; GO:0046872 42414 XR_006397297.1 0 0 10 0 16 NA NA NA NA NA NA 42415 XM_029350519.2 398 444 279 641 450 A0NLY7 4.28e-25 Isatin hydrolase (EC 3.5.2.20) (Isatin amidohydrolase) (Isatin hydrolase isoform b) (IH-b) Roseibium aggregatum (strain ATCC 25650 / DSM 13394 / JCM 20685 / NBRC 16684 / NCIMB 2208 / IAM 12614 / B1) (Stappia aggregata) tryptophan catabolic process to kynurenine [GO:0019441] GO:0004061; GO:0016812; GO:0019441; GO:0030145 42416 XM_044314915.1 34 39 20 7 57 NA NA NA NA NA NA 42417 XM_044313403.1 0 6 2 0 0 Q09575 1.92e-25 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 42418 XR_006396151.1 7 245 2 54 240 NA NA NA NA NA NA 42419 XR_006397539.1 23 34 0 7 0 NA NA NA NA NA NA 42420 XM_044310225.1 51 0 0 63 58 NA NA NA NA NA NA 42421 XM_029323913.2 18 30 0 7 29 Q95J75 4.56e-97 Mitochondrial folate transporter/carrier (Solute carrier family 25 member 32) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) folate import into mitochondrion [GO:1904947]; mitochondrial FAD transmembrane transport [GO:1990548]; mitochondrial transport [GO:0006839] GO:0005743; GO:0006839; GO:0008517; GO:1904947; GO:1990548 42422 XM_044312092.1 22 0 10 100 106 Q99MW1 6.47e-30 Serine/threonine-protein kinase 31 (EC 2.7.11.1) Mus musculus (Mouse) protein phosphorylation [GO:0006468] GO:0001669; GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0006468; GO:0106310 42423 XM_044309141.1 928 521 507 898 989 Q6ZS30 0 Neurobeachin-like protein 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein) Homo sapiens (Human) protein localization [GO:0008104] GO:0005829; GO:0008104; GO:0016020; GO:0019901 42424 XM_044309141.1 928 521 507 898 989 Q6ZS30 2.41e-133 Neurobeachin-like protein 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein) Homo sapiens (Human) protein localization [GO:0008104] GO:0005829; GO:0008104; GO:0016020; GO:0019901 42425 XM_029333101.2 24 0 0 58 0 P58307 7.66e-28 Orexin/Hypocretin receptor type 1 (Hypocretin receptor type 1) (Orexin receptor type 1) (Ox-1-R) (Ox1-R) (Ox1R) Mus musculus (Mouse) feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0004930; GO:0005886; GO:0007186; GO:0007218; GO:0007631; GO:0016499; GO:0017046; GO:0051480; GO:0070374 42426 XM_044307254.1 124 12 21 79 6 NA NA NA NA NA NA 42427 XM_044312231.1 18 0 11 117 0 NA NA NA NA NA NA 42428 XM_029355614.2 148 193 115 169 421 O42574 7.3e-21 Beta-1 adrenergic receptor (Beta-1 adrenoreceptor) (Beta-1 adrenoceptor) (x-BETA1AR) Xenopus laevis (African clawed frog) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; positive regulation of GTPase activity [GO:0043547]; positive regulation of heart contraction [GO:0045823] GO:0004940; GO:0005085; GO:0005769; GO:0005886; GO:0043547; GO:0045823; GO:0071880 42429 XR_006392204.1 0 11 0 0 24 NA NA NA NA NA NA 42430 XM_029355324.2 2931 3408 1626 1688 2292 G8HTB6 1.26e-28 ZP domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 42431 XM_044314816.1 12 0 0 0 0 NA NA NA NA NA NA 42432 XM_044308783.1 5 34 0 88 3 NA NA NA NA NA NA 42433 XM_044327310.1 2 3 3 0 32 B3EWZ5 1.01e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 42434 XM_044325623.1 66 16 18 27 51 Q8BKN5 5.24e-31 Gamma-tubulin complex component 5 (GCP-5) Mus musculus (Mouse) cytoplasmic microtubule organization [GO:0031122]; meiotic cell cycle [GO:0051321]; microtubule nucleation [GO:0007020]; mitotic cell cycle [GO:0000278]; spindle assembly [GO:0051225] GO:0000278; GO:0000922; GO:0000923; GO:0000930; GO:0000931; GO:0005813; GO:0005829; GO:0005874; GO:0007020; GO:0008017; GO:0031122; GO:0043015; GO:0051225; GO:0051321 42435 XM_029328517.2 5874 4548 4356 3665 3126 NA NA NA NA NA NA 42436 XM_029344600.2 34 11 42 1 124 A1DWM3 1.77e-23 Major facilitator superfamily domain-containing protein 6 (Macrophage MHC class I receptor 2 homolog) Sus scrofa (Pig) antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590] GO:0005886; GO:0016020; GO:0042590 42437 XR_006393761.1 0 0 17 0 0 NA NA NA NA NA NA 42438 XM_044319827.1 1223 980 863 1733 1833 P48763 2.33e-142 Sodium/hydrogen exchanger 2 (H7) (Na(+)/H(+) exchanger 2) (NHE-2) (Solute carrier family 9 member 2) Rattus norvegicus (Rat) potassium ion transmembrane transport [GO:0071805]; protein localization [GO:0008104]; proton transmembrane transport [GO:1902600]; regulation of intracellular pH [GO:0051453]; regulation of pH [GO:0006885]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814] GO:0005886; GO:0006814; GO:0006885; GO:0008104; GO:0015385; GO:0015386; GO:0016324; GO:0035725; GO:0051453; GO:0071805; GO:0098719; GO:1902600 42439 XR_006397359.1 1 0 4 8 3 NA NA NA NA NA NA 42440 XR_006397418.1 0 13 0 0 0 NA NA NA NA NA NA 42441 XM_029358618.2 56 73 97 168 87 O57422 3.44e-29 Melanopsin-B (Opsin-4B) (xMOP) Xenopus laevis (African clawed frog) phototransduction [GO:0007602]; visual perception [GO:0007601] GO:0004930; GO:0005886; GO:0007601; GO:0007602; GO:0009881 42442 XM_029341110.2 1591 483 327 1605 694 P21802 7.08e-149 Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332) Homo sapiens (Human) angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell fate commitment [GO:0045165]; cell-cell signaling [GO:0007267]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; lung-associated mesenchyme development [GO:0060484]; mammary gland bud formation [GO:0060615]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smooth muscle cell differentiation [GO:0051150]; regulation of smoothened signaling pathway [GO:0008589]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060] GO:0000122; GO:0001525; GO:0001657; GO:0001701; GO:0001837; GO:0002053; GO:0003148; GO:0003149; GO:0003416; GO:0004713; GO:0004714; GO:0005007; GO:0005524; GO:0005576; GO:0005634; GO:0005737; GO:0005794; GO:0005886; GO:0005938; GO:0006915; GO:0007169; GO:0007267; GO:0007409; GO:0008201; GO:0008284; GO:0008543; GO:0008589; GO:0009791; GO:0009880; GO:0009887; GO:0009986; GO:0010518; GO:0010839; GO:0016020; GO:0016331; GO:0017134; GO:0018108; GO:0021769; GO:0021847; GO:0021860; GO:0022612; GO:0030177; GO:0030282; GO:0030324; GO:0030855; GO:0030901; GO:0030916; GO:0031069; GO:0031410; GO:0032496; GO:0032808; GO:0033674; GO:0033688; GO:0035265; GO:0035602; GO:0035603; GO:0035604; GO:0035607; GO:0042060; GO:0042472; GO:0042476; GO:0042802; GO:0042803; GO:0043235; GO:0043410; GO:0045165; GO:0045471; GO:0045667; GO:0045787; GO:0045944; GO:0046777; GO:0048286; GO:0048333; GO:0048557; GO:0048562; GO:0048565; GO:0048568; GO:0048608; GO:0048661; GO:0048701; GO:0048705; GO:0048730; GO:0048755; GO:0048762; GO:0050679; GO:0051150; GO:0051781; GO:0055010; GO:0060045; GO:0060076; GO:0060174; GO:0060348; GO:0060349; GO:0060442; GO:0060445; GO:0060449; GO:0060463; GO:0060484; GO:0060501; GO:0060512; GO:0060523; GO:0060527; GO:0060529; GO:0060595; GO:0060601; GO:0060615; GO:0060664; GO:0060667; GO:0060670; GO:0060688; GO:0060915; GO:0060916; GO:0070372; GO:0070374; GO:0071300; GO:0071560; GO:0090263 42443 XR_003825810.2 29 29 20 25 26 NA NA NA NA NA NA 42444 XM_029343598.2 440 832 1161 155 778 NA NA NA NA NA NA 42445 XM_044327248.1 7 0 0 19 159 Q9UBD5 4.7e-175 Origin recognition complex subunit 3 (Origin recognition complex subunit Latheo) Homo sapiens (Human) DNA replication [GO:0006260]; DNA replication initiation [GO:0006270]; glial cell proliferation [GO:0014009]; neural precursor cell proliferation [GO:0061351]; regulation of DNA replication [GO:0006275] GO:0000781; GO:0000785; GO:0000808; GO:0003688; GO:0005654; GO:0005656; GO:0005664; GO:0006260; GO:0006270; GO:0006275; GO:0014009; GO:0016604; GO:0031261; GO:0061351 42446 XM_044322277.1 70 13 48 67 49 Q9UBS5 9.25e-100 Gamma-aminobutyric acid type B receptor subunit 1 (GABA-B receptor 1) (GABA-B-R1) (GABA-BR1) (GABABR1) (Gb1) Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of dopamine secretion [GO:0033602]; negative regulation of epinephrine secretion [GO:0032811]; negative regulation of gamma-aminobutyric acid secretion [GO:0014053]; negative regulation of synaptic transmission [GO:0050805]; neuron-glial cell signaling [GO:0150099]; osteoblast differentiation [GO:0001649]; positive regulation of glutamate secretion [GO:0014049]; positive regulation of growth hormone secretion [GO:0060124]; response to ethanol [GO:0045471]; response to nicotine [GO:0035094]; synaptic transmission, GABAergic [GO:0051932] GO:0001649; GO:0004888; GO:0004965; GO:0005615; GO:0005789; GO:0005886; GO:0007193; GO:0007194; GO:0007214; GO:0008021; GO:0008285; GO:0014049; GO:0014053; GO:0030673; GO:0031966; GO:0032811; GO:0033602; GO:0035094; GO:0038039; GO:0042734; GO:0043025; GO:0043197; GO:0043198; GO:0045121; GO:0045211; GO:0045471; GO:0046982; GO:0050805; GO:0051932; GO:0060124; GO:0098685; GO:0098978; GO:0098982; GO:0099579; GO:0150047; GO:0150099; GO:1902712; GO:1990430 42447 XM_029331265.2 1984 2129 1752 2418 2845 O60476 0 Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB (EC 3.2.1.113) (Mannosidase alpha class 1A member 2) (Processing alpha-1,2-mannosidase IB) (Alpha-1,2-mannosidase IB) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; Golgi apparatus mannose trimming [GO:1904381]; lung alveolus development [GO:0048286]; N-glycan processing [GO:0006491]; protein glycosylation [GO:0006486]; respiratory gaseous exchange by respiratory system [GO:0007585] GO:0000139; GO:0004571; GO:0005509; GO:0005783; GO:0005794; GO:0005975; GO:0006486; GO:0006491; GO:0007585; GO:0016020; GO:0048286; GO:0070062; GO:1904381 42448 XR_006394311.1 3 3 0 2 9 NA NA NA NA NA NA 42449 XM_029327439.2 6918 8482 4669 6136 5334 P63031 1.45e-45 Mitochondrial pyruvate carrier 1 (Apoptosis-regulating basic protein) (Brain protein 44-like protein) Rattus norvegicus (Rat) cellular response to leukemia inhibitory factor [GO:1990830]; mitochondrial pyruvate transmembrane transport [GO:0006850] GO:0005743; GO:0006850; GO:0050833; GO:1990830 42450 XM_044328154.1 0 9 0 27 46 NA NA NA NA NA NA 42451 XM_029324572.2 6 0 0 0 12 NA NA NA NA NA NA 42452 XR_006391488.1 50 14 66 27 196 NA NA NA NA NA NA 42453 XM_029333462.2 1619 881 810 781 763 NA NA NA NA NA NA 42454 XM_044329350.1 361 249 288 398 271 Q96AY4 5.85e-98 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 42455 XM_044329350.1 361 249 288 398 271 Q96AY4 4.93e-68 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 42456 XM_044325336.1 5 16 24 3 70 NA NA NA NA NA NA 42457 XM_029355699.2 589 526 397 405 518 Q9Z2E1 6.75e-56 Methyl-CpG-binding domain protein 2 (Methyl-CpG-binding protein MBD2) Mus musculus (Mouse) aging [GO:0007568]; cellular response to organic cyclic compound [GO:0071407]; chromatin remodeling [GO:0006338]; DNA methylation-dependent heterochromatin formation [GO:0006346]; embryonic organ development [GO:0048568]; heart development [GO:0007507]; histone deacetylation [GO:0016575]; maternal behavior [GO:0042711]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of chromatin binding [GO:0035563]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of Wnt signaling pathway [GO:0030177]; protein-containing complex assembly [GO:0065003]; regulation of cell population proliferation [GO:0042127]; regulation of DNA methylation [GO:0044030]; response to estradiol [GO:0032355]; response to mechanical stimulus [GO:0009612]; response to nutrient levels [GO:0031667]; Wnt signaling pathway [GO:0016055] GO:0000118; GO:0000122; GO:0000785; GO:0000792; GO:0003677; GO:0003682; GO:0003729; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006338; GO:0006346; GO:0007507; GO:0007568; GO:0008327; GO:0009612; GO:0016055; GO:0016575; GO:0016581; GO:0019904; GO:0030177; GO:0031667; GO:0032355; GO:0035197; GO:0035563; GO:0042127; GO:0042711; GO:0044030; GO:0045893; GO:0048568; GO:0060090; GO:0065003; GO:0070742; GO:0071407 42458 XM_044308549.1 0 0 0 0 7 NA NA NA NA NA NA 42459 XM_044310748.1 0 0 0 0 17 NA NA NA NA NA NA 42460 XR_006397862.1 33 61 50 51 18 NA NA NA NA NA NA 42461 XM_029351446.2 37 13 10 0 7 P58308 5.69e-23 Orexin receptor type 2 (Ox-2-R) (Ox2-R) (Ox2R) (Hypocretin receptor type 2) Mus musculus (Mouse) circadian sleep/wake cycle process [GO:0022410]; feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; locomotion [GO:0040011]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; regulation of circadian sleep/wake cycle, wakefulness [GO:0010840]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0004930; GO:0005886; GO:0007186; GO:0007200; GO:0007218; GO:0007631; GO:0010840; GO:0016499; GO:0017046; GO:0022410; GO:0040011; GO:0051480 42462 XM_044320904.1 95 46 101 94 16 NA NA NA NA NA NA 42463 XM_044308385.1 124 51 7 29 63 NA NA NA NA NA NA 42464 XM_044309248.1 1 0 7 0 9 NA NA NA NA NA NA 42465 XM_044311126.1 0 0 0 21 0 NA NA NA NA NA NA 42466 XR_006397745.1 14 0 13 4 0 NA NA NA NA NA NA 42467 XM_044324967.1 30 11 5 0 118 P81274 2.79e-32 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 42468 XM_044324967.1 30 11 5 0 118 P81274 8.27e-28 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 42469 XM_044324967.1 30 11 5 0 118 P81274 9.03e-24 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 42470 XM_029350031.2 1757 1197 691 960 1193 Q6DRF9 1.21e-79 WD repeat-containing protein 55 Danio rerio (Zebrafish) (Brachydanio rerio) eye development [GO:0001654]; pharynx development [GO:0060465]; rRNA processing [GO:0006364]; swim bladder development [GO:0048794]; thymus development [GO:0048538] GO:0001654; GO:0005730; GO:0006364; GO:0048538; GO:0048794; GO:0060465 42471 XM_029338665.2 646 334 356 494 333 Q8BZT9 1.53e-66 Purine nucleoside phosphorylase LACC1 (EC 2.4.2.1) (Adenosine deaminase LACC1) (EC 3.5.4.4) (Fatty acid metabolism-immunity nexus) (Guanosine phosphorylase LACC1) (Laccase domain-containing protein 1) (S-methyl-5'-thioadenosine phosphorylase LACC1) (EC 2.4.2.28) Mus musculus (Mouse) inflammatory response [GO:0006954]; innate immune response [GO:0045087]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of cytokine production involved in immune response [GO:0002720]; regulation of cellular pH [GO:0030641]; regulation of inflammatory response [GO:0050727]; regulation of purine nucleotide metabolic process [GO:1900542] GO:0002221; GO:0002720; GO:0004000; GO:0004731; GO:0005507; GO:0005634; GO:0005737; GO:0005777; GO:0005783; GO:0006954; GO:0017061; GO:0030641; GO:0045087; GO:0046936; GO:0047975; GO:0050727; GO:0070431; GO:1900542 42472 XM_044321233.1 204 190 187 530 713 NA NA NA NA NA NA 42473 XM_029358657.2 33 16 1 27 30 Q14833 7.06e-81 Metabotropic glutamate receptor 4 (mGluR4) Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway [GO:0007196]; chemical synaptic transmission [GO:0007268]; G protein-coupled glutamate receptor signaling pathway [GO:0007216]; neurotransmitter secretion [GO:0007269]; positive regulation of MAPK cascade [GO:0043410]; regulation of neuron apoptotic process [GO:0043523]; regulation of synaptic transmission, glutamatergic [GO:0051966] GO:0001640; GO:0004930; GO:0005886; GO:0007196; GO:0007216; GO:0007268; GO:0007269; GO:0008066; GO:0031410; GO:0043410; GO:0043523; GO:0051966; GO:0098793 42474 XM_029341896.2 3567 2656 1818 3082 3094 Q6PD03 0 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform (PP2A B subunit isoform B'-alpha) (PP2A B subunit isoform B56-alpha) (PP2A B subunit isoform PR61-alpha) (PR61alpha) (PP2A B subunit isoform R5-alpha) Mus musculus (Mouse) negative regulation of lipid kinase activity [GO:0090219]; negative regulation of protein localization to plasma membrane [GO:1903077]; positive regulation of protein dephosphorylation [GO:0035307]; protein dephosphorylation [GO:0006470]; signal transduction [GO:0007165] GO:0000159; GO:0000775; GO:0004721; GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0006470; GO:0007165; GO:0016020; GO:0019900; GO:0030018; GO:0031430; GO:0035307; GO:0072542; GO:0090219; GO:1903077 42475 XM_044328171.1 184 434 164 150 139 NA NA NA NA NA NA 42476 XM_029354054.2 361 275 166 153 359 Q05B18 2.51e-116 Protein SHQ1 homolog Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) box H/ACA snoRNP assembly [GO:0000493]; ribonucleoprotein complex assembly [GO:0022618] GO:0000493; GO:0005654; GO:0005829; GO:0022618 42477 XM_044306878.1 60 128 41 1 23 Q6PD21 1.86e-43 SH2 domain-containing adapter protein B Mus musculus (Mouse) angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; B cell proliferation [GO:0042100]; blood vessel development [GO:0001568]; blood vessel morphogenesis [GO:0048514]; hematopoietic stem cell proliferation [GO:0071425]; hemopoiesis [GO:0030097]; negative regulation of oocyte maturation [GO:1900194]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of T-helper cell differentiation [GO:0045624]; T cell receptor signaling pathway [GO:0050852] GO:0001525; GO:0001568; GO:0001784; GO:0005654; GO:0005829; GO:0005886; GO:0006469; GO:0006915; GO:0030097; GO:0030159; GO:0036464; GO:0042100; GO:0045624; GO:0045931; GO:0048514; GO:0050852; GO:0071425; GO:1900194 42478 XR_003824341.2 0 5 0 0 10 NA NA NA NA NA NA 42479 XM_044318958.1 809 0 0 0 739 Q12933 4.25e-25 TNF receptor-associated factor 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF2) (RING-type E3 ubiquitin transferase TRAF2) (Tumor necrosis factor type 2 receptor-associated protein 3) Homo sapiens (Human) activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular response to nitric oxide [GO:0071732]; interleukin-17-mediated signaling pathway [GO:0097400]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; mRNA stabilization [GO:0048255]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron death [GO:1901215]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein K63-linked ubiquitination [GO:0070534]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin production [GO:0002637]; regulation of protein-containing complex assembly [GO:0043254]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; signal transduction involved in regulation of gene expression [GO:0023019]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000151; GO:0002637; GO:0002726; GO:0002947; GO:0004842; GO:0005164; GO:0005174; GO:0005654; GO:0005829; GO:0005938; GO:0007165; GO:0007250; GO:0008270; GO:0009898; GO:0012506; GO:0019899; GO:0019901; GO:0019903; GO:0023019; GO:0030163; GO:0030674; GO:0031435; GO:0031625; GO:0031996; GO:0032743; GO:0033209; GO:0034351; GO:0034976; GO:0035631; GO:0042802; GO:0042981; GO:0043120; GO:0043122; GO:0043123; GO:0043254; GO:0043507; GO:0044877; GO:0045121; GO:0046330; GO:0046625; GO:0048255; GO:0051091; GO:0051092; GO:0051865; GO:0065003; GO:0070059; GO:0070534; GO:0071732; GO:0097057; GO:0097300; GO:0097400; GO:1901215; GO:1903265; GO:1903721; GO:1990604; GO:2001238 42480 XM_044323137.1 273 18 9 42 42 P16157 3.01e-28 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 42481 XR_006398195.1 362 315 158 185 257 Q53GS7 5.61e-29 mRNA export factor GLE1 (hGLE1) (GLE1 RNA export mediator) (GLE1-like protein) (Nucleoporin GLE1) Homo sapiens (Human) mRNA export from nucleus [GO:0006406]; nucleocytoplasmic transport [GO:0006913]; poly(A)+ mRNA export from nucleus [GO:0016973]; protein transport [GO:0015031] GO:0000822; GO:0005543; GO:0005615; GO:0005635; GO:0005643; GO:0005730; GO:0005737; GO:0005813; GO:0005814; GO:0005829; GO:0006406; GO:0006913; GO:0015031; GO:0016020; GO:0016973; GO:0031369; GO:0031965; GO:0036064; GO:0042802; GO:0044614 42482 XM_044320076.1 6 15 7 5 12 P04323 1.17e-60 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 42483 XM_029353166.2 146 110 14 90 70 NA NA NA NA NA NA 42484 XM_044328233.1 4 42 0 61 77 O60290 2.09e-66 Zinc finger protein 862 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006355; GO:0046872; GO:0046983 42485 XR_006396289.1 102 20 26 31 38 NA NA NA NA NA NA 42486 XM_044328544.1 0 0 0 0 128 NA NA NA NA NA NA 42487 XM_029334076.2 1138 518 470 524 882 Q8N695 9.99e-100 Sodium-coupled monocarboxylate transporter 1 (Apical iodide transporter) (Electrogenic sodium monocarboxylate cotransporter) (Sodium iodide-related cotransporter) (Solute carrier family 5 member 8) Homo sapiens (Human) apoptotic process [GO:0006915]; ion transport [GO:0006811]; NAD biosynthesis via nicotinamide riboside salvage pathway [GO:0034356]; propanoate transport [GO:0015730]; sodium ion transport [GO:0006814] GO:0005343; GO:0005886; GO:0006811; GO:0006814; GO:0006915; GO:0008028; GO:0015129; GO:0015293; GO:0015552; GO:0015730; GO:0016324; GO:0022803; GO:0034356; GO:0070062; GO:0140161 42488 XR_003825759.2 0 10 0 48 0 NA NA NA NA NA NA 42489 XM_044326786.1 0 0 0 0 9 NA NA NA NA NA NA 42490 XM_044322764.1 0 54 5 3 36 NA NA NA NA NA NA 42491 XM_029339284.2 7 10 15 10 24 NA NA NA NA NA NA 42492 XM_029334181.2 0 0 0 0 12 P25931 4.85e-34 RYamide receptor (Neuropeptide Y-like receptor) (NPY-R) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218] GO:0001653; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0016020 42493 XM_029352759.2 27 371 218 79 292 NA NA NA NA NA NA 42494 XM_044306964.1 56 39 38 171 136 B3EWZ5 3.15e-27 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 42495 XM_044306964.1 56 39 38 171 136 B3EWZ5 1.52e-24 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 42496 XM_044306964.1 56 39 38 171 136 B3EWZ5 4.18e-23 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 42497 XM_044306964.1 56 39 38 171 136 B3EWZ5 1.72e-22 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 42498 XM_044306964.1 56 39 38 171 136 B3EWZ5 7.17e-22 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 42499 XM_044312903.1 120 32 98 21 97 P55006 6.47e-76 Retinol dehydrogenase 7 (EC 1.1.1.105) (Retinol dehydrogenase 3) (Retinol dehydrogenase type III) (RODH III) Rattus norvegicus (Rat) retinol metabolic process [GO:0042572]; steroid metabolic process [GO:0008202] GO:0004745; GO:0005783; GO:0008202; GO:0016491; GO:0042572; GO:0043231 42500 XM_029324148.2 631 480 411 653 990 Q6DEL2 0 Putative lipid scramblase CLPTM1 (Cleft lip and palate transmembrane protein 1 homolog) Danio rerio (Zebrafish) (Brachydanio rerio) cell differentiation [GO:0030154] GO:0012505; GO:0016020; GO:0030154 42501 XM_044315645.1 103 0 49 32 103 Q27889 1.61e-70 Serine/threonine-protein phosphatase 2B catalytic subunit 2 (EC 3.1.3.16) (Calmodulin-dependent calcineurin A2 subunit) Drosophila melanogaster (Fruit fly) calcineurin-mediated signaling [GO:0097720]; female meiotic nuclear division [GO:0007143]; meiotic cell cycle [GO:0051321]; protein dephosphorylation [GO:0006470]; regulation of embryonic development [GO:0045995]; sleep [GO:0030431]; wing disc development [GO:0035220] GO:0004722; GO:0004723; GO:0005516; GO:0005737; GO:0005955; GO:0006470; GO:0007143; GO:0017018; GO:0030431; GO:0033192; GO:0035220; GO:0045995; GO:0046872; GO:0051321; GO:0097720 42502 XM_044327305.1 443 815 345 858 350 NA NA NA NA NA NA 42503 XM_029340985.2 576 486 645 127 325 A2VDU3 6.47e-126 Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) Bos taurus (Bovine) apoptotic process [GO:0006915]; I-kappaB phosphorylation [GO:0007252]; JNK cascade [GO:0007254]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of JUN kinase activity [GO:0043507] GO:0000287; GO:0004709; GO:0005524; GO:0005737; GO:0005886; GO:0006915; GO:0007252; GO:0007254; GO:0043123; GO:0043507; GO:0106310 42504 XM_029356104.2 0 110 0 308 0 NA NA NA NA NA NA 42505 XM_029347235.2 95 133 0 24 0 NA NA NA NA NA NA 42506 XR_006394299.1 2 0 1 1 33 NA NA NA NA NA NA 42507 XM_044320914.1 6 3 14 0 20 NA NA NA NA NA NA 42508 XM_029334218.2 2 0 2 13 0 Q6DIL6 4.47e-29 Protein FAM124A Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA NA 42509 XR_006392880.1 41 2 25 5 151 NA NA NA NA NA NA 42510 XM_044317621.1 0 28 0 0 0 A2AUY4 3.61e-99 Bromodomain adjacent to zinc finger domain protein 2B Mus musculus (Mouse) NA GO:0003677; GO:0005634; GO:0046872 42511 XM_044317621.1 0 28 0 0 0 A2AUY4 2.06e-43 Bromodomain adjacent to zinc finger domain protein 2B Mus musculus (Mouse) NA GO:0003677; GO:0005634; GO:0046872 42512 XM_029348108.2 682 1033 337 651 628 NA NA NA NA NA NA 42513 XM_029328565.2 276 804 34 641 119 Q8IUC4 1.15e-111 Rhophilin-2 (76 kDa RhoB effector protein) (GTP-Rho-binding protein 2) (p76RBE) Homo sapiens (Human) glomerular filtration [GO:0003094]; negative regulation of stress fiber assembly [GO:0051497]; signal transduction [GO:0007165] GO:0003094; GO:0005829; GO:0005886; GO:0007165; GO:0048471; GO:0051497 42514 XR_003827035.2 39 0 0 25 21 NA NA NA NA NA NA 42515 XR_006391998.1 0 0 0 18 17 NA NA NA NA NA NA 42516 XM_044324675.1 95 103 54 114 139 Q80XJ3 1.13e-102 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 42517 XM_044324675.1 95 103 54 114 139 Q80XJ3 1.56e-101 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 42518 XM_044324675.1 95 103 54 114 139 Q80XJ3 6.99e-101 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 42519 XM_044324675.1 95 103 54 114 139 Q80XJ3 1.18e-96 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 42520 XM_044324675.1 95 103 54 114 139 Q80XJ3 5.04e-94 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 42521 XM_044324675.1 95 103 54 114 139 Q80XJ3 1.65e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 42522 XM_044320814.1 11 0 12 14 12 P04323 1.25e-61 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 42523 XM_044320931.1 20 204 48 73 436 Q7RTR2 1.07e-44 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 42524 XM_044320931.1 20 204 48 73 436 Q7RTR2 1.96e-41 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 42525 XM_044320931.1 20 204 48 73 436 Q7RTR2 1.64e-40 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 42526 XM_044320931.1 20 204 48 73 436 Q7RTR2 1.9e-39 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 42527 XM_044320931.1 20 204 48 73 436 Q7RTR2 1.71e-37 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 42528 XM_044320931.1 20 204 48 73 436 Q7RTR2 2.77e-37 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 42529 XM_044320931.1 20 204 48 73 436 Q7RTR2 1.33e-26 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 42530 XM_044320931.1 20 204 48 73 436 Q7RTR2 6.87e-23 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 42531 XM_029332403.2 4927 2491 3040 2195 1759 NA NA NA NA NA NA 42532 XM_044322379.1 0 0 328 0 0 NA NA NA NA NA NA 42533 XM_029336258.2 2895 3889 2203 2449 2707 NA NA NA NA NA NA 42534 XM_044322666.1 2 0 0 1 20 NA NA NA NA NA NA 42535 XM_029344698.2 0 0 6 13 0 Q98925 1.31e-23 Interferon regulatory factor 2 (IRF-2) Gallus gallus (Chicken) immune system process [GO:0002376]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0002376; GO:0005634; GO:0006357 42536 XM_029348479.2 1195 990 1657 1861 1364 Q8K596 7.66e-74 Sodium/calcium exchanger 2 (Na(+)/Ca(2+)-exchange protein 2) (Solute carrier family 8 member 2) Mus musculus (Mouse) calcium ion export across plasma membrane [GO:1990034]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport into cytosol [GO:0060402]; cell communication [GO:0007154]; cellular calcium ion homeostasis [GO:0006874]; cognition [GO:0050890]; learning [GO:0007612]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; metal ion transport [GO:0030001]; modulation of excitatory postsynaptic potential [GO:0098815]; neuron cellular homeostasis [GO:0070050]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; regulation of action potential firing pattern [GO:0099608]; regulation of calcineurin-mediated signaling [GO:0106056]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; response to ischemia [GO:0002931]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814]; synapse organization [GO:0050808] GO:0002931; GO:0005432; GO:0005516; GO:0005739; GO:0005874; GO:0005886; GO:0006814; GO:0006874; GO:0007154; GO:0007611; GO:0007612; GO:0007613; GO:0010468; GO:0014069; GO:0015081; GO:0015085; GO:0016020; GO:0016323; GO:0030001; GO:0030424; GO:0030425; GO:0035725; GO:0042383; GO:0042995; GO:0043025; GO:0043197; GO:0043679; GO:0045202; GO:0045211; GO:0046872; GO:0048172; GO:0050808; GO:0050890; GO:0051480; GO:0060291; GO:0060402; GO:0070050; GO:0070588; GO:0071902; GO:0098703; GO:0098793; GO:0098794; GO:0098815; GO:0099608; GO:0106056; GO:1905060; GO:1990034 42537 XM_044323649.1 60 51 39 93 170 P95896 1.82e-35 Amidase (EC 3.5.1.4) Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) NA GO:0004040; GO:0043864 42538 XM_029329454.2 1710 1613 1423 1488 1896 Q8BHR2 3.39e-33 Ecto-NOX disulfide-thiol exchanger 1 (Constitutive Ecto-NOX) (cNOX) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)] Mus musculus (Mouse) ultradian rhythm [GO:0007624] GO:0003723; GO:0003756; GO:0003954; GO:0005615; GO:0005886; GO:0007624; GO:0009897 42539 XM_029344269.2 353 383 212 134 155 NA NA NA NA NA NA 42540 XM_044317844.1 1 0 29 2 31 NA NA NA NA NA NA 42541 XM_044319907.1 993 776 637 1136 954 Q6NRS2 1.35e-94 Solute carrier family 66 member 2 (PQ-loop repeat-containing protein 1) Xenopus laevis (African clawed frog) NA GO:0016020 42542 XM_029354210.2 29 4 12 63 17 NA NA NA NA NA NA 42543 XM_044319833.1 16 17 12 10 26 NA NA NA NA NA NA 42544 XM_044329026.1 215 29 178 37 136 NA NA NA NA NA NA 42545 XM_029354779.2 12 0 24 17 7 NA NA NA NA NA NA 42546 XM_044318770.1 26 9 19 39 61 NA NA NA NA NA NA 42547 XM_044328400.1 433 160 333 488 1105 NA NA NA NA NA NA 42548 XM_029332802.2 0 18 0 0 0 Q9I8C7 2.3e-95 Neuronal acetylcholine receptor subunit alpha-10 (Alpha 10 nAChR) (Nicotinic acetylcholine receptor subunit alpha-10) (NACHR alpha-10) Gallus gallus (Chicken) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; response to auditory stimulus [GO:0010996]; signal transduction [GO:0007165] GO:0004888; GO:0005231; GO:0005262; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0010996; GO:0022848; GO:0030594; GO:0034220; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051899; GO:1904315 42549 XM_044322060.1 116 0 0 0 23 Q7RTR2 5.3e-66 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 42550 XM_044322060.1 116 0 0 0 23 Q7RTR2 7.35e-65 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 42551 XM_044322060.1 116 0 0 0 23 Q7RTR2 8.96e-41 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 42552 XM_029336525.2 309 199 39 84 148 NA NA NA NA NA NA 42553 XM_044315350.1 0 0 4 11 1 P04323 1.95e-71 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 42554 XM_029353906.2 37 61 57 20 30 Q09575 1.6e-31 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 42555 XM_029358596.2 4496 5032 2566 3065 3046 NA NA NA NA NA NA 42556 XM_029326810.2 6 0 12 9 14 Q96DM1 8.56e-104 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 42557 XR_006394952.1 27 43 53 39 85 NA NA NA NA NA NA 42558 XM_044312071.1 26 15 38 8 37 NA NA NA NA NA NA 42559 XM_044315558.1 97 72 15 64 94 NA NA NA NA NA NA 42560 XM_029344896.2 120 199 49 712 122 NA NA NA NA NA NA 42561 XM_044311833.1 909 188 476 786 969 A0JMV4 3.3e-72 RNA-binding protein 5-A (RNA-binding motif protein 5-A) Xenopus laevis (African clawed frog) positive regulation of apoptotic process [GO:0043065]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; spliceosomal complex assembly [GO:0000245] GO:0000245; GO:0000381; GO:0003729; GO:0005634; GO:0005681; GO:0043065; GO:0046872 42562 XM_044311833.1 909 188 476 786 969 A0JMV4 8.39e-39 RNA-binding protein 5-A (RNA-binding motif protein 5-A) Xenopus laevis (African clawed frog) positive regulation of apoptotic process [GO:0043065]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; spliceosomal complex assembly [GO:0000245] GO:0000245; GO:0000381; GO:0003729; GO:0005634; GO:0005681; GO:0043065; GO:0046872 42563 XM_029353059.2 0 0 0 9 0 NA NA NA NA NA NA 42564 XR_006391545.1 47 0 48 0 241 NA NA NA NA NA NA 42565 XM_044315256.1 5 176 21 0 0 NA NA NA NA NA NA 42566 XM_044322882.1 7327 2910 2568 11405 9613 O46392 3.26e-59 Collagen alpha-2(I) chain (Alpha-2 type I collagen) Canis lupus familiaris (Dog) (Canis familiaris) NA GO:0005201; GO:0005576; GO:0005581; GO:0046872 42567 XM_044313721.1 45 0 24 62 6 NA NA NA NA NA NA 42568 XM_029331196.2 12 42 0 14 14 Q805E5 2.84e-34 Carbohydrate sulfotransferase 14 (EC 2.8.2.-) (Dermatan 4-sulfotransferase 1) (D4ST-1) (zD4ST-1) Danio rerio (Zebrafish) (Brachydanio rerio) carbohydrate biosynthetic process [GO:0016051]; dermatan sulfate proteoglycan metabolic process [GO:0050655] GO:0000139; GO:0001537; GO:0008146; GO:0016051; GO:0050655 42569 XM_029325101.2 888 302 463 762 437 A7RPT4 3.11e-116 NAD(P)H-hydrate epimerase (EC 5.1.99.6) (NAD(P)HX epimerase) Nematostella vectensis (Starlet sea anemone) NA GO:0000166; GO:0046872; GO:0052856; GO:0052857 42570 XM_044314228.1 42 29 29 94 13 Q7TSV4 9.29e-118 Phosphopentomutase (EC 5.4.2.7) (Glucose phosphomutase 2) (Phosphodeoxyribomutase) (Phosphoglucomutase-1) (Phosphoglucomutase-2) (PGM 2) (EC 5.4.2.2) Mus musculus (Mouse) glucose metabolic process [GO:0006006]; glycogen catabolic process [GO:0005980]; purine ribonucleoside salvage [GO:0006166] GO:0000287; GO:0004614; GO:0005829; GO:0005980; GO:0006006; GO:0006166; GO:0008973 42571 XM_029354017.2 0 11 12 4 6 NA NA NA NA NA NA 42572 XM_029341304.2 12 1 0 7 7 NA NA NA NA NA NA 42573 XM_029339138.2 17 26 46 5 27 NA NA NA NA NA NA 42574 XM_044317036.1 1326 806 353 483 342 P79888 1.25e-99 S-adenosylmethionine decarboxylase proenzyme (AdoMetDC) (SAMDC) (EC 4.1.1.50) [Cleaved into: S-adenosylmethionine decarboxylase alpha chain; S-adenosylmethionine decarboxylase beta chain] Xenopus laevis (African clawed frog) spermidine biosynthetic process [GO:0008295]; spermine biosynthetic process [GO:0006597] GO:0004014; GO:0006597; GO:0008295 42575 XM_029330411.2 17 0 0 0 0 P58308 2.39e-38 Orexin receptor type 2 (Ox-2-R) (Ox2-R) (Ox2R) (Hypocretin receptor type 2) Mus musculus (Mouse) circadian sleep/wake cycle process [GO:0022410]; feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; locomotion [GO:0040011]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; regulation of circadian sleep/wake cycle, wakefulness [GO:0010840]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0004930; GO:0005886; GO:0007186; GO:0007200; GO:0007218; GO:0007631; GO:0010840; GO:0016499; GO:0017046; GO:0022410; GO:0040011; GO:0051480 42576 XM_029333704.2 9 0 0 2 5 NA NA NA NA NA NA 42577 XM_044321216.1 3010 2444 2836 2402 3154 A3KPW9 1.01e-33 Large proline-rich protein BAG6 (BCL2-associated athanogene 6) (HLA-B-associated transcript 3) Danio rerio (Zebrafish) (Brachydanio rerio) brain development [GO:0007420]; chromatin organization [GO:0006325]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; ER-associated misfolded protein catabolic process [GO:0071712]; internal peptidyl-lysine acetylation [GO:0018393]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; lung development [GO:0030324]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of proteolysis [GO:0045861]; proteasomal protein catabolic process [GO:0010498]; protein stabilization [GO:0050821]; regulation of apoptotic process [GO:0042981]; regulation of embryonic development [GO:0045995]; spermatogenesis [GO:0007283]; synaptonemal complex assembly [GO:0007130]; tail-anchored membrane protein insertion into ER membrane [GO:0071816]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0001822; GO:0005576; GO:0005634; GO:0005829; GO:0006325; GO:0006511; GO:0007130; GO:0007283; GO:0007420; GO:0010498; GO:0018393; GO:0030324; GO:0030433; GO:0031593; GO:0032435; GO:0042771; GO:0042981; GO:0043022; GO:0045861; GO:0045995; GO:0050821; GO:0051787; GO:0061857; GO:0070059; GO:0070628; GO:0071712; GO:0071816; GO:0071818 42578 XM_044306874.1 145 0 0 126 49 Q15858 0 Sodium channel protein type 9 subunit alpha (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1) (PN1) (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) Homo sapiens (Human) behavioral response to formalin induced pain [GO:0061368]; circadian rhythm [GO:0007623]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; inflammatory response [GO:0006954]; membrane depolarization during action potential [GO:0086010]; negative regulation of action potential [GO:0045759]; neuronal action potential [GO:0019228]; post-embryonic development [GO:0009791]; regulation of ion transmembrane transport [GO:0034765]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to toxic substance [GO:0009636]; sensory perception of pain [GO:0019233]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814] GO:0001518; GO:0005244; GO:0005248; GO:0005886; GO:0006814; GO:0006954; GO:0007623; GO:0009408; GO:0009409; GO:0009636; GO:0009791; GO:0019228; GO:0019233; GO:0030424; GO:0031402; GO:0034765; GO:0035725; GO:0045759; GO:0050965; GO:0050974; GO:0061368; GO:0086010 42579 XM_044306874.1 145 0 0 126 49 Q15858 2.14e-67 Sodium channel protein type 9 subunit alpha (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1) (PN1) (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) Homo sapiens (Human) behavioral response to formalin induced pain [GO:0061368]; circadian rhythm [GO:0007623]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; inflammatory response [GO:0006954]; membrane depolarization during action potential [GO:0086010]; negative regulation of action potential [GO:0045759]; neuronal action potential [GO:0019228]; post-embryonic development [GO:0009791]; regulation of ion transmembrane transport [GO:0034765]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to toxic substance [GO:0009636]; sensory perception of pain [GO:0019233]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814] GO:0001518; GO:0005244; GO:0005248; GO:0005886; GO:0006814; GO:0006954; GO:0007623; GO:0009408; GO:0009409; GO:0009636; GO:0009791; GO:0019228; GO:0019233; GO:0030424; GO:0031402; GO:0034765; GO:0035725; GO:0045759; GO:0050965; GO:0050974; GO:0061368; GO:0086010 42580 XM_029350064.2 339 352 546 914 2121 NA NA NA NA NA NA 42581 XM_029348029.2 2765 2358 1423 2430 2508 P36876 0 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform (PP2A subunit B isoform B55-alpha) (PP2A subunit B isoform BRA) (PP2A subunit B isoform PR55-alpha) (PP2A subunit B isoform R2-alpha) (PP2A subunit B isoform alpha) Rattus norvegicus (Rat) protein dephosphorylation [GO:0006470]; response to morphine [GO:0043278] GO:0000159; GO:0005829; GO:0006470; GO:0019888; GO:0043278; GO:0044877; GO:0045202; GO:0048156; GO:0051721; GO:0098978 42582 XM_029337740.2 1052 604 420 741 898 Q6GQ39 6.28e-86 Transmembrane protein 135 (Peroxisomal membrane protein 52) (PMP52) Xenopus laevis (African clawed frog) regulation of mitochondrial fission [GO:0090140] GO:0005739; GO:0005778; GO:0031966; GO:0090140 42583 XM_044323936.1 1571 1094 666 2159 1106 O95263 0 High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B (HsPDE8B) (EC 3.1.4.53) (Cell proliferation-inducing gene 22 protein) Homo sapiens (Human) behavioral fear response [GO:0001662]; cAMP catabolic process [GO:0006198]; negative regulation of steroid hormone biosynthetic process [GO:0090032]; neuromuscular process controlling balance [GO:0050885]; operant conditioning [GO:0035106]; signal transduction [GO:0007165]; visual learning [GO:0008542] GO:0001662; GO:0004114; GO:0004115; GO:0005829; GO:0006198; GO:0007165; GO:0008542; GO:0035106; GO:0046872; GO:0050885; GO:0090032 42584 XR_006396259.1 386 73 56 195 69 NA NA NA NA NA NA 42585 XR_003826275.2 65 84 115 47 80 NA NA NA NA NA NA 42586 XM_044316099.1 81 123 86 64 222 Q0P5F0 1.51e-89 Lysosomal acid phosphatase (LAP) (EC 3.1.3.2) Bos taurus (Bovine) dephosphorylation [GO:0016311]; lysosome organization [GO:0007040] GO:0003993; GO:0005764; GO:0005765; GO:0007040; GO:0016311; GO:0016791; GO:0043202 42587 XM_044315410.1 263 398 80 277 377 NA NA NA NA NA NA 42588 XM_029350281.2 17 0 12 20 23 Q766D5 8.5e-39 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Mus musculus (Mouse) chondroitin sulfate biosynthetic process [GO:0030206] GO:0008376; GO:0030206; GO:0032580; GO:0033842; GO:0047238 42589 XM_029337371.2 115 66 66 63 93 NA NA NA NA NA NA 42590 XR_006396661.1 0 0 1 3 26 NA NA NA NA NA NA 42591 XM_044312429.1 94 103 49 0 3 NA NA NA NA NA NA 42592 XM_044317806.1 434 304 230 282 317 Q5R868 2.31e-34 Post-GPI attachment to proteins factor 4 (Post-GPI attachment to proteins GalNAc transferase 4) (Transmembrane protein 246) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) GPI anchor biosynthetic process [GO:0006506] GO:0000139; GO:0006506; GO:0016757 42593 XM_044325771.1 0 0 4 0 28 Q09575 6.46e-23 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 42594 XM_044318188.1 0 0 0 0 9 NA NA NA NA NA NA 42595 XM_029337194.2 1516 776 864 939 701 NA NA NA NA NA NA 42596 XM_029345635.2 447 3394 312 48 1727 NA NA NA NA NA NA 42597 XM_029358587.2 11 102 11 221 172 Q3KR59 7.16e-110 Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.4.19.12) (Deubiquitinating enzyme 10) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) Rattus norvegicus (Rat) autophagy [GO:0006914]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to interleukin-1 [GO:0071347]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA repair [GO:0006281]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; protein deubiquitination [GO:0016579]; regulation of autophagy [GO:0010506]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0002039; GO:0004197; GO:0004843; GO:0005634; GO:0005737; GO:0005769; GO:0005829; GO:0006281; GO:0006511; GO:0006914; GO:0006974; GO:0010506; GO:0016579; GO:0030330; GO:0032991; GO:0043124; GO:0044325; GO:0071347 42598 XM_044316694.1 0 62 39 0 0 NA NA NA NA NA NA 42599 XR_006396172.1 22 11 14 8 30 NA NA NA NA NA NA 42600 XM_044320260.1 762 1861 893 734 1342 NA NA NA NA NA NA 42601 XR_006395413.1 28 0 0 1 12 NA NA NA NA NA NA 42602 XM_044315933.1 0 0 0 0 45 NA NA NA NA NA NA 42603 XM_044321606.1 611 389 189 1226 1624 NA NA NA NA NA NA 42604 XM_029358632.2 0 0 0 18 0 Q9GZQ4 1.38e-21 Neuromedin-U receptor 2 (NMU-R2) (G-protein coupled receptor FM-4) (G-protein coupled receptor TGR-1) Homo sapiens (Human) arachidonic acid secretion [GO:0050482]; calcium ion transport [GO:0006816]; calcium-mediated signaling [GO:0019722]; cell-cell signaling [GO:0007267]; central nervous system development [GO:0007417]; feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; grooming behavior [GO:0007625]; inositol phosphate-mediated signaling [GO:0048016]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; reduction of food intake in response to dietary excess [GO:0002023]; regulation of sensory perception of pain [GO:0051930]; regulation of smooth muscle contraction [GO:0006940]; response to pain [GO:0048265] GO:0001607; GO:0002023; GO:0004930; GO:0005229; GO:0005525; GO:0005886; GO:0006816; GO:0006940; GO:0007186; GO:0007200; GO:0007204; GO:0007218; GO:0007267; GO:0007417; GO:0007625; GO:0007631; GO:0008188; GO:0016020; GO:0019722; GO:0042924; GO:0048016; GO:0048265; GO:0050482; GO:0051930 42605 XR_006396346.1 9 14 12 31 23 NA NA NA NA NA NA 42606 XM_044321556.1 48 0 20 0 84 NA NA NA NA NA NA 42607 XM_044324437.1 16 11 7 9 0 NA NA NA NA NA NA 42608 XM_029352430.2 53 71 25 44 97 NA NA NA NA NA NA 42609 XM_044316047.1 11 0 2 7 7 P00727 3.78e-144 Cytosol aminopeptidase (EC 3.4.11.1) (Cysteinylglycine-S-conjugate dipeptidase) (EC 3.4.13.23) (Leucine aminopeptidase 3) (LAP-3) (Leucyl aminopeptidase) (LAP) (Peptidase S) (Proline aminopeptidase) (EC 3.4.11.5) (Prolyl aminopeptidase) Bos taurus (Bovine) proteolysis [GO:0006508] GO:0004180; GO:0005654; GO:0005737; GO:0005739; GO:0005829; GO:0006508; GO:0008233; GO:0016805; GO:0030145; GO:0030496; GO:0070006; GO:0097718 42610 XM_029341356.2 151 83 125 198 273 Q9UI26 0 Importin-11 (Imp11) (Ran-binding protein 11) (RanBP11) Homo sapiens (Human) protein import into nucleus [GO:0006606]; ribosomal protein import into nucleus [GO:0006610] GO:0005635; GO:0005654; GO:0005829; GO:0006606; GO:0006610; GO:0031267; GO:0061608 42611 XR_006391515.1 6 14 18 6 109 NA NA NA NA NA NA 42612 XM_044318741.1 1021 483 554 900 614 Q8K394 0 Inactive phospholipase C-like protein 2 (PLC-L(2)) (PLC-L2) (Phospholipase C-L2) (Phospholipase C-epsilon-2) (PLC-epsilon-2) Mus musculus (Mouse) B cell proliferation involved in immune response [GO:0002322]; B-1a B cell differentiation [GO:0002337]; gamma-aminobutyric acid signaling pathway [GO:0007214]; lipid metabolic process [GO:0006629]; negative regulation of B cell receptor signaling pathway [GO:0050859]; negative regulation of cold-induced thermogenesis [GO:0120163]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of receptor binding [GO:1900122]; regulation of synaptic transmission, GABAergic [GO:0032228] GO:0002322; GO:0002337; GO:0004435; GO:0005737; GO:0006629; GO:0007214; GO:0032228; GO:0048015; GO:0050811; GO:0050859; GO:0070679; GO:0120163; GO:1900122 42613 XR_003825209.2 42 59 72 65 30 NA NA NA NA NA NA 42614 XM_029333680.2 591 464 8 236 0 Q3ZC91 2.75e-39 Acid sphingomyelinase-like phosphodiesterase 3a (ASM-like phosphodiesterase 3a) (EC 3.1.4.-) Bos taurus (Bovine) nucleoside triphosphate catabolic process [GO:0009143] GO:0005576; GO:0005615; GO:0008081; GO:0008270; GO:0009143 42615 XM_029324644.2 473 322 191 466 151 NA NA NA NA NA NA 42616 XM_044308517.1 0 0 0 6 6 O15014 1.96e-22 Zinc finger protein 609 Homo sapiens (Human) muscle organ development [GO:0007517]; positive regulation of neuron migration [GO:2001224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of myoblast proliferation [GO:2000291]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0005634; GO:0005654; GO:0006357; GO:0007517; GO:0045944; GO:0046872; GO:1990841; GO:2000291; GO:2001224 42617 XR_006398079.1 96 79 3 22 49 NA NA NA NA NA NA 42618 XM_029327002.2 46 29 58 57 204 A8MY62 2.43e-47 Putative beta-lactamase-like 1 Homo sapiens (Human) NA NA 42619 XM_044327208.1 24 0 15 9 37 NA NA NA NA NA NA 42620 XM_044309642.1 222 296 20 0 150 Q9Z2W0 0 Aspartyl aminopeptidase (EC 3.4.11.21) Mus musculus (Mouse) proteolysis [GO:0006508] GO:0004177; GO:0005829; GO:0006508; GO:0008237; GO:0008270; GO:0042802 42621 XM_029353726.2 313 433 209 313 304 Q8BTQ0 5.93e-46 Polycomb group RING finger protein 3 (RING finger protein 3A) Mus musculus (Mouse) histone H2A-K119 monoubiquitination [GO:0036353]; inactivation of X chromosome by genomic imprinting [GO:0060819]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0005634; GO:0005654; GO:0006357; GO:0031519; GO:0035102; GO:0036353; GO:0046872; GO:0060819 42622 XM_044316005.1 562 182 154 619 538 NA NA NA NA NA NA 42623 XM_029326795.2 2 4 2 9 29 NA NA NA NA NA NA 42624 XM_044316952.1 38 39 16 64 14 NA NA NA NA NA NA 42625 XM_029325857.2 42 17 29 15 53 NA NA NA NA NA NA 42626 XM_029355344.2 1475 432 1468 1302 3942 Q7ZVH1 1.07e-39 Membrane progestin receptor gamma-A (mPR gamma-A) (Progestin and adipoQ receptor family member V-A) Danio rerio (Zebrafish) (Brachydanio rerio) oogenesis [GO:0048477] GO:0005496; GO:0016020; GO:0038023; GO:0048477 42627 XR_006397919.1 77 60 14 172 40 P11362 1.44e-60 Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331) Homo sapiens (Human) cell migration [GO:0016477]; chordate embryonic development [GO:0043009]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; MAPK cascade [GO:0000165]; neuron migration [GO:0001764]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell differentiation [GO:0045595]; regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001239]; skeletal system development [GO:0001501]; skeletal system morphogenesis [GO:0048705]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0000165; GO:0001501; GO:0001764; GO:0001837; GO:0004713; GO:0004714; GO:0005007; GO:0005524; GO:0005576; GO:0005634; GO:0005829; GO:0005886; GO:0006468; GO:0007169; GO:0008201; GO:0008284; GO:0008543; GO:0010518; GO:0010863; GO:0014068; GO:0016020; GO:0016477; GO:0017134; GO:0018108; GO:0031410; GO:0033674; GO:0042802; GO:0042803; GO:0043009; GO:0043235; GO:0043406; GO:0043410; GO:0043536; GO:0045595; GO:0045597; GO:0045666; GO:0046777; GO:0048015; GO:0048705; GO:0051897; GO:0090722; GO:1905564; GO:2000546; GO:2001239 42628 XM_029358556.2 10 0 0 1 0 NA NA NA NA NA NA 42629 XM_044316188.1 29 0 57 124 48 NA NA NA NA NA NA 42630 XM_044322303.1 0 0 3 5 19 NA NA NA NA NA NA 42631 XR_006395008.1 0 5 0 4 7 NA NA NA NA NA NA 42632 XM_044323615.1 1 18 8 68 220 NA NA NA NA NA NA 42633 XM_044325129.1 526 478 347 524 417 Q803I2 0 Endoplasmic reticulum-Golgi intermediate compartment protein 3 Danio rerio (Zebrafish) (Brachydanio rerio) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] GO:0000139; GO:0005783; GO:0005789; GO:0006888; GO:0006890; GO:0016020; GO:0030134; GO:0033116 42634 XM_044316680.1 1589 461 369 669 256 NA NA NA NA NA NA 42635 XM_044327026.1 22 3 0 5 8 NA NA NA NA NA NA 42636 XM_044321465.1 347 303 168 251 360 NA NA NA NA NA NA 42637 XM_029344868.2 5 103 3 121 54 NA NA NA NA NA NA 42638 XM_044321063.1 184 0 0 0 0 S8FIE4 1.5e-40 Laccase-1 (EC 1.10.3.2) (FpLCC1) Fomitopsis pinicola (strain FP-58527) (Brown rot fungus) NA GO:0005507; GO:0005576; GO:0016682 42639 XM_044323943.1 0 0 17 0 51 Q9CXI3 1.19e-107 DBH-like monooxygenase protein 1 (EC 1.14.17.-) (DBH-related protein) (Monooxygenase X) Mus musculus (Mouse) dopamine catabolic process [GO:0042420]; norepinephrine biosynthetic process [GO:0042421]; octopamine biosynthetic process [GO:0006589] GO:0004500; GO:0005507; GO:0005615; GO:0005789; GO:0006589; GO:0030667; GO:0042420; GO:0042421 42640 XM_044320012.1 38 32 41 153 39 P54886 0 Delta-1-pyrroline-5-carboxylate synthase (P5CS) (Aldehyde dehydrogenase family 18 member A1) [Includes: Glutamate 5-kinase (GK) (EC 2.7.2.11) (Gamma-glutamyl kinase); Gamma-glutamyl phosphate reductase (GPR) (EC 1.2.1.41) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase)] Homo sapiens (Human) citrulline biosynthetic process [GO:0019240]; glutamate metabolic process [GO:0006536]; L-proline biosynthetic process [GO:0055129]; ornithine biosynthetic process [GO:0006592]; phosphorylation [GO:0016310]; proline biosynthetic process [GO:0006561] GO:0003723; GO:0004349; GO:0004350; GO:0005524; GO:0005739; GO:0005743; GO:0006536; GO:0006561; GO:0006592; GO:0016310; GO:0019240; GO:0042802; GO:0055129 42641 XR_006394982.1 4 5 0 10 0 NA NA NA NA NA NA 42642 XM_029328987.2 82 87 39 104 73 NA NA NA NA NA NA 42643 XR_006393251.1 21 31 25 5 77 NA NA NA NA NA NA 42644 XM_029338616.2 6 20 5 1 69 NA NA NA NA NA NA 42645 XM_044320613.1 21 26 0 105 92 NA NA NA NA NA NA 42646 XM_029328656.2 1980 1441 477 1371 682 C7G3A0 2.67e-123 Metallophosphoesterase 1 (EC 3.1.-.-) (Post-GPI attachment to proteins factor 5) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; GPI anchor biosynthetic process [GO:0006506] GO:0005654; GO:0005793; GO:0005801; GO:0006506; GO:0006888; GO:0030145; GO:0033116; GO:0034235; GO:0062050; GO:0070971 42647 XM_044328916.1 127 404 320 325 304 NA NA NA NA NA NA 42648 XM_044319508.1 587 279 91 221 194 P69525 2.87e-72 Transmembrane protease serine 9 (EC 3.4.21.-) (Polyserase-I) (Polyserine protease 1) (Polyserase-1) [Cleaved into: Serase-1; Serase-2; Serase-3] Mus musculus (Mouse) plasminogen activation [GO:0031639]; proteolysis [GO:0006508] GO:0004252; GO:0005886; GO:0006508; GO:0008236; GO:0031639 42649 XM_044319508.1 587 279 91 221 194 P69525 3.8e-37 Transmembrane protease serine 9 (EC 3.4.21.-) (Polyserase-I) (Polyserine protease 1) (Polyserase-1) [Cleaved into: Serase-1; Serase-2; Serase-3] Mus musculus (Mouse) plasminogen activation [GO:0031639]; proteolysis [GO:0006508] GO:0004252; GO:0005886; GO:0006508; GO:0008236; GO:0031639 42650 XM_044319508.1 587 279 91 221 194 P69525 2.1e-35 Transmembrane protease serine 9 (EC 3.4.21.-) (Polyserase-I) (Polyserine protease 1) (Polyserase-1) [Cleaved into: Serase-1; Serase-2; Serase-3] Mus musculus (Mouse) plasminogen activation [GO:0031639]; proteolysis [GO:0006508] GO:0004252; GO:0005886; GO:0006508; GO:0008236; GO:0031639 42651 XM_044319508.1 587 279 91 221 194 P69525 1.05e-34 Transmembrane protease serine 9 (EC 3.4.21.-) (Polyserase-I) (Polyserine protease 1) (Polyserase-1) [Cleaved into: Serase-1; Serase-2; Serase-3] Mus musculus (Mouse) plasminogen activation [GO:0031639]; proteolysis [GO:0006508] GO:0004252; GO:0005886; GO:0006508; GO:0008236; GO:0031639 42652 XM_044319508.1 587 279 91 221 194 P69525 9.91e-32 Transmembrane protease serine 9 (EC 3.4.21.-) (Polyserase-I) (Polyserine protease 1) (Polyserase-1) [Cleaved into: Serase-1; Serase-2; Serase-3] Mus musculus (Mouse) plasminogen activation [GO:0031639]; proteolysis [GO:0006508] GO:0004252; GO:0005886; GO:0006508; GO:0008236; GO:0031639 42653 XM_029346100.2 6193 8303 2246 10188 5059 Q3U435 6.52e-102 Matrix metalloproteinase-25 (MMP-25) (EC 3.4.24.-) Mus musculus (Mouse) collagen catabolic process [GO:0030574]; extracellular matrix organization [GO:0030198]; hard palate development [GO:0060022]; proteolysis [GO:0006508] GO:0004222; GO:0005886; GO:0006508; GO:0008270; GO:0009986; GO:0016504; GO:0030198; GO:0030574; GO:0031012; GO:0060022 42654 XM_029346100.2 6193 8303 2246 10188 5059 Q3U435 1.94e-78 Matrix metalloproteinase-25 (MMP-25) (EC 3.4.24.-) Mus musculus (Mouse) collagen catabolic process [GO:0030574]; extracellular matrix organization [GO:0030198]; hard palate development [GO:0060022]; proteolysis [GO:0006508] GO:0004222; GO:0005886; GO:0006508; GO:0008270; GO:0009986; GO:0016504; GO:0030198; GO:0030574; GO:0031012; GO:0060022 42655 XM_044327104.1 543 578 585 935 399 B8RJM0 0 Uncharacterized skeletal organic matrix protein 3 (Uncharacterized SOMP-3) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 42656 XM_029337111.2 47 93 270 230 365 A2RV80 1.69e-69 GRAM domain-containing protein 4 Xenopus laevis (African clawed frog) apoptotic process [GO:0006915] GO:0005789; GO:0006915; GO:0031966 42657 XM_044307041.1 0 0 0 67 35 NA NA NA NA NA NA 42658 XR_006393498.1 0 0 0 19 0 NA NA NA NA NA NA 42659 XM_044309923.1 50 6 0 45 11 NA NA NA NA NA NA 42660 XM_029350675.2 291 324 114 150 392 NA NA NA NA NA NA 42661 XR_003826739.2 116 178 112 91 109 NA NA NA NA NA NA 42662 XM_044326530.1 365 30 312 305 595 Q49UX2 4.45e-176 Dihydroxy-acid dehydratase 2 (DAD 2) (EC 4.2.1.9) Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229 / NCIMB 8711 / NCTC 7292 / S-41) isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099] GO:0000287; GO:0004160; GO:0009097; GO:0009099; GO:0051537 42663 XM_029338160.2 2106 1937 1481 2359 2108 E9PU28 0 Inosine-5'-monophosphate dehydrogenase 2 (IMP dehydrogenase 2) (IMPD 2) (IMPDH 2) (EC 1.1.1.205) Rattus norvegicus (Rat) 'de novo' XMP biosynthetic process [GO:0097294]; cellular response to interleukin-4 [GO:0071353]; circadian rhythm [GO:0007623]; GMP biosynthetic process [GO:0006177]; GTP biosynthetic process [GO:0006183]; lymphocyte proliferation [GO:0046651]; purine nucleotide biosynthetic process [GO:0006164]; retina development in camera-type eye [GO:0060041] GO:0000166; GO:0003938; GO:0005634; GO:0005737; GO:0005829; GO:0006164; GO:0006177; GO:0006183; GO:0007623; GO:0042802; GO:0046651; GO:0046872; GO:0060041; GO:0071353; GO:0097294 42664 XM_029330758.2 28 31 25 33 40 NA NA NA NA NA NA 42665 XM_029345578.2 872 850 754 816 1119 P12815 1.64e-69 Programmed cell death protein 6 (ALG-257) (Apoptosis-linked gene 2 protein) (ALG-2) (PMP41) Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cellular response to heat [GO:0034605]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein monoubiquitination [GO:1902527]; response to calcium ion [GO:0051592]; vascular endothelial growth factor receptor-2 signaling pathway [GO:0036324] GO:0000287; GO:0001525; GO:0001938; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005783; GO:0005789; GO:0005829; GO:0006886; GO:0006888; GO:0006915; GO:0006919; GO:0010595; GO:0014029; GO:0014032; GO:0030127; GO:0030674; GO:0030948; GO:0031410; GO:0031463; GO:0032007; GO:0034605; GO:0036324; GO:0042802; GO:0042803; GO:0043280; GO:0043495; GO:0045766; GO:0046983; GO:0048208; GO:0048306; GO:0051592; GO:0051898; GO:0070971; GO:1902527; GO:1990756 42666 XM_029323684.2 112 104 105 109 433 B5X441 1.91e-45 F-box/LRR-repeat protein 15 Salmo salar (Atlantic salmon) bone mineralization [GO:0030282]; dorsal/ventral pattern formation [GO:0009953]; G2/M transition of mitotic cell cycle [GO:0000086]; positive regulation of BMP signaling pathway [GO:0030513]; protein ubiquitination [GO:0016567]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0000086; GO:0005737; GO:0009953; GO:0016567; GO:0019005; GO:0030282; GO:0030513; GO:0031146 42667 XM_044312576.1 321 202 387 386 535 Q80U62 1.24e-102 Run domain Beclin-1-interacting and cysteine-rich domain-containing protein (Rubicon) Mus musculus (Mouse) autophagy [GO:0006914]; endocytosis [GO:0006897]; immune system process [GO:0002376]; negative regulation of autophagosome maturation [GO:1901097]; negative regulation of autophagy [GO:0010507]; negative regulation of endocytosis [GO:0045806]; negative regulation of phosphatidylinositol 3-kinase activity [GO:0043553] GO:0002376; GO:0005654; GO:0005764; GO:0005769; GO:0005770; GO:0005829; GO:0006897; GO:0006914; GO:0010507; GO:0043231; GO:0043553; GO:0045806; GO:1901097; GO:1901981 42668 XM_044319322.1 55 73 22 84 90 NA NA NA NA NA NA 42669 XM_029342549.2 115 46 22 12 9 NA NA NA NA NA NA 42670 XM_029351482.2 187 141 119 104 210 NA NA NA NA NA NA 42671 XM_044327863.1 1552 1063 1206 1775 1536 Q9Y2I7 5.63e-107 1-phosphatidylinositol 3-phosphate 5-kinase (Phosphatidylinositol 3-phosphate 5-kinase) (EC 2.7.1.150) (FYVE finger-containing phosphoinositide kinase) (PIKfyve) (Phosphatidylinositol 3-phosphate 5-kinase type III) (PIPkin-III) (Type III PIP kinase) (Serine-protein kinase PIKFYVE) (EC 2.7.11.1) Homo sapiens (Human) 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process [GO:1903100]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; intracellular signal transduction [GO:0035556]; melanosome organization [GO:0032438]; myelin assembly [GO:0032288]; neutrophil chemotaxis [GO:0030593]; peptidyl-serine autophosphorylation [GO:0036289]; phagosome maturation [GO:0090382]; phagosome-lysosome fusion [GO:0090385]; phosphatidylinositol 5-phosphate metabolic process [GO:1904562]; phosphatidylinositol biosynthetic process [GO:0006661]; protein localization to nucleus [GO:0034504]; protein targeting to membrane [GO:0006612]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of autophagosome assembly [GO:2000785]; regulation of reactive oxygen species biosynthetic process [GO:1903426]; retrograde transport, endosome to Golgi [GO:0042147] GO:0000139; GO:0000285; GO:0004674; GO:0005524; GO:0005829; GO:0005911; GO:0006612; GO:0006661; GO:0008270; GO:0010008; GO:0012506; GO:0016308; GO:0019065; GO:0019886; GO:0030593; GO:0030670; GO:0031410; GO:0031901; GO:0031902; GO:0032288; GO:0032438; GO:0034504; GO:0035556; GO:0036289; GO:0042147; GO:0043813; GO:0045121; GO:0048471; GO:0052810; GO:0090382; GO:0090385; GO:0106310; GO:1903100; GO:1903426; GO:1904562; GO:2000785 42672 XM_044327863.1 1552 1063 1206 1775 1536 Q9Y2I7 2.02e-101 1-phosphatidylinositol 3-phosphate 5-kinase (Phosphatidylinositol 3-phosphate 5-kinase) (EC 2.7.1.150) (FYVE finger-containing phosphoinositide kinase) (PIKfyve) (Phosphatidylinositol 3-phosphate 5-kinase type III) (PIPkin-III) (Type III PIP kinase) (Serine-protein kinase PIKFYVE) (EC 2.7.11.1) Homo sapiens (Human) 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process [GO:1903100]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; intracellular signal transduction [GO:0035556]; melanosome organization [GO:0032438]; myelin assembly [GO:0032288]; neutrophil chemotaxis [GO:0030593]; peptidyl-serine autophosphorylation [GO:0036289]; phagosome maturation [GO:0090382]; phagosome-lysosome fusion [GO:0090385]; phosphatidylinositol 5-phosphate metabolic process [GO:1904562]; phosphatidylinositol biosynthetic process [GO:0006661]; protein localization to nucleus [GO:0034504]; protein targeting to membrane [GO:0006612]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of autophagosome assembly [GO:2000785]; regulation of reactive oxygen species biosynthetic process [GO:1903426]; retrograde transport, endosome to Golgi [GO:0042147] GO:0000139; GO:0000285; GO:0004674; GO:0005524; GO:0005829; GO:0005911; GO:0006612; GO:0006661; GO:0008270; GO:0010008; GO:0012506; GO:0016308; GO:0019065; GO:0019886; GO:0030593; GO:0030670; GO:0031410; GO:0031901; GO:0031902; GO:0032288; GO:0032438; GO:0034504; GO:0035556; GO:0036289; GO:0042147; GO:0043813; GO:0045121; GO:0048471; GO:0052810; GO:0090382; GO:0090385; GO:0106310; GO:1903100; GO:1903426; GO:1904562; GO:2000785 42673 XM_044327863.1 1552 1063 1206 1775 1536 Q9Y2I7 3.36e-85 1-phosphatidylinositol 3-phosphate 5-kinase (Phosphatidylinositol 3-phosphate 5-kinase) (EC 2.7.1.150) (FYVE finger-containing phosphoinositide kinase) (PIKfyve) (Phosphatidylinositol 3-phosphate 5-kinase type III) (PIPkin-III) (Type III PIP kinase) (Serine-protein kinase PIKFYVE) (EC 2.7.11.1) Homo sapiens (Human) 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process [GO:1903100]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; intracellular signal transduction [GO:0035556]; melanosome organization [GO:0032438]; myelin assembly [GO:0032288]; neutrophil chemotaxis [GO:0030593]; peptidyl-serine autophosphorylation [GO:0036289]; phagosome maturation [GO:0090382]; phagosome-lysosome fusion [GO:0090385]; phosphatidylinositol 5-phosphate metabolic process [GO:1904562]; phosphatidylinositol biosynthetic process [GO:0006661]; protein localization to nucleus [GO:0034504]; protein targeting to membrane [GO:0006612]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of autophagosome assembly [GO:2000785]; regulation of reactive oxygen species biosynthetic process [GO:1903426]; retrograde transport, endosome to Golgi [GO:0042147] GO:0000139; GO:0000285; GO:0004674; GO:0005524; GO:0005829; GO:0005911; GO:0006612; GO:0006661; GO:0008270; GO:0010008; GO:0012506; GO:0016308; GO:0019065; GO:0019886; GO:0030593; GO:0030670; GO:0031410; GO:0031901; GO:0031902; GO:0032288; GO:0032438; GO:0034504; GO:0035556; GO:0036289; GO:0042147; GO:0043813; GO:0045121; GO:0048471; GO:0052810; GO:0090382; GO:0090385; GO:0106310; GO:1903100; GO:1903426; GO:1904562; GO:2000785 42674 XM_044327863.1 1552 1063 1206 1775 1536 Q9Y2I7 6.19e-32 1-phosphatidylinositol 3-phosphate 5-kinase (Phosphatidylinositol 3-phosphate 5-kinase) (EC 2.7.1.150) (FYVE finger-containing phosphoinositide kinase) (PIKfyve) (Phosphatidylinositol 3-phosphate 5-kinase type III) (PIPkin-III) (Type III PIP kinase) (Serine-protein kinase PIKFYVE) (EC 2.7.11.1) Homo sapiens (Human) 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process [GO:1903100]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; intracellular signal transduction [GO:0035556]; melanosome organization [GO:0032438]; myelin assembly [GO:0032288]; neutrophil chemotaxis [GO:0030593]; peptidyl-serine autophosphorylation [GO:0036289]; phagosome maturation [GO:0090382]; phagosome-lysosome fusion [GO:0090385]; phosphatidylinositol 5-phosphate metabolic process [GO:1904562]; phosphatidylinositol biosynthetic process [GO:0006661]; protein localization to nucleus [GO:0034504]; protein targeting to membrane [GO:0006612]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of autophagosome assembly [GO:2000785]; regulation of reactive oxygen species biosynthetic process [GO:1903426]; retrograde transport, endosome to Golgi [GO:0042147] GO:0000139; GO:0000285; GO:0004674; GO:0005524; GO:0005829; GO:0005911; GO:0006612; GO:0006661; GO:0008270; GO:0010008; GO:0012506; GO:0016308; GO:0019065; GO:0019886; GO:0030593; GO:0030670; GO:0031410; GO:0031901; GO:0031902; GO:0032288; GO:0032438; GO:0034504; GO:0035556; GO:0036289; GO:0042147; GO:0043813; GO:0045121; GO:0048471; GO:0052810; GO:0090382; GO:0090385; GO:0106310; GO:1903100; GO:1903426; GO:1904562; GO:2000785 42675 XM_044318135.1 1352 808 548 1055 825 NA NA NA NA NA NA 42676 XR_006395727.1 35 63 44 79 34 NA NA NA NA NA NA 42677 XM_044320821.1 0 4 9 9 24 NA NA NA NA NA NA 42678 XM_029358085.2 60 116 92 93 64 Q9EQD2 2.08e-26 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 42679 XM_029326900.2 456 470 658 408 478 Q4KLG9 5.89e-65 AN1-type zinc finger protein 2B (Arsenite-inducible RNA-associated protein-like protein) (AIRAP-like protein) Rattus norvegicus (Rat) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein targeting to ER [GO:0045047]; regulation of insulin-like growth factor receptor signaling pathway [GO:0043567]; SRP-dependent cotranslational protein targeting to membrane, translocation [GO:0006616] GO:0000502; GO:0005737; GO:0005783; GO:0005789; GO:0006616; GO:0008270; GO:0016020; GO:0031593; GO:0036435; GO:0043130; GO:0043161; GO:0043567; GO:0045047 42680 XM_029338510.2 42 373 176 69 455 O08658 1.97e-111 Nuclear pore complex protein Nup88 (88 kDa nucleoporin) (Nucleoporin Nup84) (Nucleoporin Nup88) Rattus norvegicus (Rat) mitotic cell cycle [GO:0000278]; mRNA export from nucleus [GO:0006406]; protein import into nucleus [GO:0006606]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056] GO:0000055; GO:0000056; GO:0000278; GO:0005635; GO:0005643; GO:0005654; GO:0006406; GO:0006606; GO:0017056 42681 XM_044315764.1 195 508 88 618 343 NA NA NA NA NA NA 42682 XM_044307077.1 0 136 0 0 30 NA NA NA NA NA NA 42683 XM_044312344.1 141 25 0 33 22 NA NA NA NA NA NA 42684 XM_044325456.1 83 100 45 74 73 O46640 1.09e-53 Amine sulfotransferase (EC 2.8.2.3) (AST-RB1) (Sulfotransferase 3A1) (ST3A1) Oryctolagus cuniculus (Rabbit) NA GO:0005737; GO:0047685 42685 XM_044328454.1 1645 1163 769 1524 1374 Q9C0C7 3.8e-63 Activating molecule in BECN1-regulated autophagy protein 1 (DDB1- and CUL4-associated factor 3) Homo sapiens (Human) autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cellular response to starvation [GO:0009267]; mitophagy [GO:0000423]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; neural tube development [GO:0021915]; positive regulation of autophagy [GO:0010508]; positive regulation of free ubiquitin chain polymerization [GO:1904544]; positive regulation of mitophagy [GO:1901526]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of regulatory T cell differentiation [GO:0045591]; protein polyubiquitination [GO:0000209]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of transcription by RNA polymerase II [GO:0006357]; response to mitochondrial depolarisation [GO:0098780] GO:0000045; GO:0000209; GO:0000422; GO:0000423; GO:0005634; GO:0005737; GO:0005739; GO:0005741; GO:0005776; GO:0005783; GO:0005829; GO:0005856; GO:0005925; GO:0005930; GO:0006357; GO:0006914; GO:0007049; GO:0008285; GO:0009267; GO:0010508; GO:0010667; GO:0019903; GO:0021915; GO:0030154; GO:0031625; GO:0035307; GO:0043231; GO:0043524; GO:0043552; GO:0045335; GO:0045591; GO:0048471; GO:0051020; GO:0080008; GO:0098780; GO:1901526; GO:1904544; GO:1990756; GO:2000045 42686 XM_044328454.1 1645 1163 769 1524 1374 Q9C0C7 1.98e-54 Activating molecule in BECN1-regulated autophagy protein 1 (DDB1- and CUL4-associated factor 3) Homo sapiens (Human) autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cellular response to starvation [GO:0009267]; mitophagy [GO:0000423]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; neural tube development [GO:0021915]; positive regulation of autophagy [GO:0010508]; positive regulation of free ubiquitin chain polymerization [GO:1904544]; positive regulation of mitophagy [GO:1901526]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of regulatory T cell differentiation [GO:0045591]; protein polyubiquitination [GO:0000209]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of transcription by RNA polymerase II [GO:0006357]; response to mitochondrial depolarisation [GO:0098780] GO:0000045; GO:0000209; GO:0000422; GO:0000423; GO:0005634; GO:0005737; GO:0005739; GO:0005741; GO:0005776; GO:0005783; GO:0005829; GO:0005856; GO:0005925; GO:0005930; GO:0006357; GO:0006914; GO:0007049; GO:0008285; GO:0009267; GO:0010508; GO:0010667; GO:0019903; GO:0021915; GO:0030154; GO:0031625; GO:0035307; GO:0043231; GO:0043524; GO:0043552; GO:0045335; GO:0045591; GO:0048471; GO:0051020; GO:0080008; GO:0098780; GO:1901526; GO:1904544; GO:1990756; GO:2000045 42687 XM_029356493.2 1352 1940 1555 2667 1150 NA NA NA NA NA NA 42688 XM_044328510.1 601 293 204 384 291 P85037 9.43e-128 Forkhead box protein K1 (Myocyte nuclear factor) (MNF) Homo sapiens (Human) canonical glycolysis [GO:0061621]; cell differentiation [GO:0030154]; cellular glucose homeostasis [GO:0001678]; muscle organ development [GO:0007517]; negative regulation of autophagy [GO:0010507]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of glucose metabolic process [GO:0010906]; regulation of transcription by RNA polymerase II [GO:0006357]; response to starvation [GO:0042594] GO:0000785; GO:0000976; GO:0000978; GO:0000981; GO:0001227; GO:0001678; GO:0003700; GO:0005634; GO:0005654; GO:0005737; GO:0006357; GO:0007517; GO:0010507; GO:0010906; GO:0030154; GO:0042594; GO:0045892; GO:0045893; GO:0061621; GO:0071889; GO:1990837 42689 XM_044322103.1 80 155 0 239 0 Q9UA35 3.74e-148 Solute carrier family 28 member 3 (Concentrative Na(+)-nucleoside cotransporter 3) (hfCNT) Eptatretus stoutii (Pacific hagfish) NA GO:0005337; GO:0005886; GO:0015293 42690 XM_029339021.2 50 43 0 0 72 NA NA NA NA NA NA 42691 XM_029348050.2 199 89 105 185 344 NA NA NA NA NA NA 42692 XM_029344378.2 10 0 70 0 1 NA NA NA NA NA NA 42693 XM_029323608.2 0 8 0 40 0 Q8WZA2 0 Rap guanine nucleotide exchange factor 4 (Exchange factor directly activated by cAMP 2) (Exchange protein directly activated by cAMP 2) (EPAC 2) (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) Homo sapiens (Human) adaptive immune response [GO:0002250]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; calcium-ion regulated exocytosis [GO:0017156]; G protein-coupled receptor signaling pathway [GO:0007186]; insulin secretion [GO:0030073]; positive regulation of GTPase activity [GO:0043547]; positive regulation of insulin secretion [GO:0032024]; Ras protein signal transduction [GO:0007265]; regulation of exocytosis [GO:0017157]; regulation of synaptic vesicle cycle [GO:0098693] GO:0002250; GO:0005085; GO:0005096; GO:0005829; GO:0005886; GO:0007186; GO:0007189; GO:0007265; GO:0016020; GO:0017156; GO:0017157; GO:0030073; GO:0030552; GO:0030674; GO:0031267; GO:0032024; GO:0043547; GO:0098686; GO:0098693 42694 XM_044315231.1 1321 344 709 301 467 Q567Y6 2.28e-61 Intraflagellar transport protein 22 homolog (Rab-like protein 5) Danio rerio (Zebrafish) (Brachydanio rerio) intracellular protein transport [GO:0006886] GO:0003924; GO:0005525; GO:0006886; GO:0012505; GO:0030992 42695 XM_044308067.1 772 651 948 2905 1346 O70244 2.38e-53 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 42696 XM_044308067.1 772 651 948 2905 1346 O70244 2.65e-44 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 42697 XM_044308067.1 772 651 948 2905 1346 O70244 7.97e-40 Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; cobalamin catabolic process [GO:0042366]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; endocytic hemoglobin import into cell [GO:0020028]; establishment of localization in cell [GO:0051649]; in utero embryonic development [GO:0001701]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; response to bacterium [GO:0009617]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766] GO:0001701; GO:0005509; GO:0005737; GO:0005765; GO:0005768; GO:0005783; GO:0005794; GO:0005798; GO:0005886; GO:0005903; GO:0005905; GO:0006766; GO:0006898; GO:0007584; GO:0008203; GO:0009235; GO:0009617; GO:0010008; GO:0015889; GO:0016020; GO:0016324; GO:0020028; GO:0030135; GO:0030139; GO:0030492; GO:0030666; GO:0031419; GO:0031526; GO:0031528; GO:0032991; GO:0038023; GO:0038024; GO:0042366; GO:0042802; GO:0042803; GO:0042953; GO:0043202; GO:0043235; GO:0045177; GO:0051649; GO:0070062 42698 XM_029330744.2 0 67 0 0 0 Q91820 5.78e-150 Aurora kinase A-A (EC 2.7.11.1) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (Serine/threonine-protein kinase 6-A) (Serine/threonine-protein kinase Eg2-A) (pEg2) (Serine/threonine-protein kinase aurora-A) (p46Eg265) Xenopus laevis (African clawed frog) cell division [GO:0051301]; meiotic spindle organization [GO:0000212]; mitotic centrosome separation [GO:0007100]; mitotic spindle assembly [GO:0090307]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777] GO:0000212; GO:0000922; GO:0004674; GO:0005524; GO:0005737; GO:0005813; GO:0005876; GO:0007100; GO:0008017; GO:0018105; GO:0019894; GO:0046777; GO:0051301; GO:0090307; GO:0106310 42699 XM_044311691.1 147 15 70 139 382 P35555 0 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 42700 XM_044311691.1 147 15 70 139 382 P35555 0 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 42701 XM_044311691.1 147 15 70 139 382 P35555 0 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 42702 XM_044311691.1 147 15 70 139 382 P35555 0 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 42703 XM_044311691.1 147 15 70 139 382 P35555 0 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 42704 XM_044311691.1 147 15 70 139 382 P35555 0 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 42705 XM_044311691.1 147 15 70 139 382 P35555 0 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 42706 XM_044310291.1 126 15 47 114 88 Q80XJ3 1.22e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 42707 XM_044311898.1 596 295 429 534 611 Q96AY4 2.21e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 42708 XM_044311898.1 596 295 429 534 611 Q96AY4 3.18e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 42709 XM_044311898.1 596 295 429 534 611 Q96AY4 3.99e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 42710 XM_044311898.1 596 295 429 534 611 Q96AY4 2.04e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 42711 XM_044311898.1 596 295 429 534 611 Q96AY4 3.36e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 42712 XM_044311898.1 596 295 429 534 611 Q96AY4 1.02e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 42713 XM_044311898.1 596 295 429 534 611 Q96AY4 1.52e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 42714 XM_044311470.1 8 0 1 5 13 O00602 3.51e-82 Ficolin-1 (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin-alpha) (M-ficolin) Homo sapiens (Human) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation, lectin pathway [GO:0001867]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of viral entry into host cell [GO:0046597]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of opsonization [GO:1903028]; protein localization to cell surface [GO:0034394]; proteolysis [GO:0006508]; recognition of apoptotic cell [GO:0043654] GO:0001664; GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005576; GO:0005581; GO:0005615; GO:0006508; GO:0007186; GO:0009897; GO:0030246; GO:0031232; GO:0032757; GO:0033691; GO:0034394; GO:0034774; GO:0038187; GO:0043654; GO:0046597; GO:0046872; GO:0062023; GO:0097367; GO:1903028; GO:1904813; GO:1905370 42715 XM_029339822.2 2084 1738 1262 2113 2441 P70645 1.08e-173 Bleomycin hydrolase (BH) (BLM hydrolase) (BMH) (EC 3.4.22.40) Rattus norvegicus (Rat) homocysteine catabolic process [GO:0043418]; proteolysis [GO:0006508]; response to toxic substance [GO:0009636]; response to xenobiotic stimulus [GO:0009410] GO:0004177; GO:0004197; GO:0005737; GO:0006508; GO:0008233; GO:0008234; GO:0009410; GO:0009636; GO:0042802; GO:0043418 42716 XM_044323570.1 0 0 0 27 55 NA NA NA NA NA NA 42717 XR_003827677.2 52 58 49 60 94 Q96DM1 1.17e-49 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 42718 XR_003827677.2 52 58 49 60 94 Q96DM1 1.17e-49 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 42719 XR_006391556.1 1 1 0 11 15 NA NA NA NA NA NA 42720 XM_044326912.1 0 0 2 10 71 NA NA NA NA NA NA 42721 XM_044326696.1 622 265 172 375 476 NA NA NA NA NA NA 42722 XM_044307240.1 174 41 52 182 302 Q9UGM3 5.94e-123 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 42723 XM_044307240.1 174 41 52 182 302 Q9UGM3 4.3e-120 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 42724 XM_044307240.1 174 41 52 182 302 Q9UGM3 1.36e-111 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 42725 XM_044307240.1 174 41 52 182 302 Q9UGM3 2.48e-75 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 42726 XR_006395312.1 5 0 0 0 13 NA NA NA NA NA NA 42727 XM_029336942.2 3115 2936 1412 1782 1194 NA NA NA NA NA NA 42728 XM_044323754.1 12 23 24 50 25 NA NA NA NA NA NA 42729 XM_044310717.1 49 0 24 142 2 NA NA NA NA NA NA 42730 XM_044319971.1 299 92 0 58 0 Q00168 1.04e-66 Calcium/calmodulin-dependent protein kinase type II alpha chain (CaM-kinase II alpha chain) (EC 2.7.11.17) Drosophila melanogaster (Fruit fly) cellular response to starvation [GO:0009267]; chemical synaptic transmission [GO:0007268]; courtship behavior [GO:0007619]; learning or memory [GO:0007611]; long-term memory [GO:0007616]; male courtship behavior [GO:0008049]; negative regulation of cytokine production [GO:0001818]; negative regulation of lipid storage [GO:0010888]; neuromuscular junction development [GO:0007528]; peptidyl-threonine autophosphorylation [GO:1990443]; positive regulation of synaptic transmission, dopaminergic [GO:0032226]; protein phosphorylation [GO:0006468]; regulation of filopodium assembly [GO:0051489]; regulation of ovulation [GO:0060278]; regulation of synaptic assembly at neuromuscular junction [GO:0008582] GO:0001818; GO:0004674; GO:0004683; GO:0005516; GO:0005524; GO:0005737; GO:0006468; GO:0007268; GO:0007528; GO:0007611; GO:0007616; GO:0007619; GO:0008049; GO:0008582; GO:0009267; GO:0010888; GO:0030424; GO:0030425; GO:0032226; GO:0043005; GO:0045211; GO:0048786; GO:0051489; GO:0060278; GO:0106310; GO:1990443 42731 XM_029341234.2 59 26 0 137 33 P21758 3.71e-22 Macrophage scavenger receptor types I and II (Macrophage acetylated LDL receptor I and II) (CD antigen CD204) Bos taurus (Bovine) amyloid-beta clearance [GO:0097242]; cholesterol transport [GO:0030301]; establishment of localization in cell [GO:0051649]; lipoprotein transport [GO:0042953]; negative regulation of gene expression [GO:0010629]; phagocytosis, engulfment [GO:0006911]; plasma lipoprotein particle clearance [GO:0034381]; positive regulation of cholesterol storage [GO:0010886]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; protein homotrimerization [GO:0070207]; receptor-mediated endocytosis [GO:0006898]; zymogen activation [GO:0031638] GO:0001540; GO:0004252; GO:0005044; GO:0005581; GO:0005886; GO:0006898; GO:0006911; GO:0010629; GO:0010744; GO:0010886; GO:0019899; GO:0030169; GO:0030301; GO:0030544; GO:0031638; GO:0034362; GO:0034381; GO:0042802; GO:0042953; GO:0051649; GO:0051879; GO:0070207; GO:0097242; GO:0140313 42732 XM_044318138.1 48 31 33 134 189 Q8IYB1 2.28e-21 Nucleotidyltransferase MB21D2 (EC 2.7.7.-) (Mab-21 domain-containing protein 2) (hMB21D2) Homo sapiens (Human) NA GO:0016779; GO:0044877; GO:0045296 42733 XM_029343082.2 0 0 31 0 0 NA NA NA NA NA NA 42734 XM_029341391.2 653 469 489 732 1033 Q91ZV7 5.55e-54 Plexin domain-containing protein 1 (Tumor endothelial marker 7) Mus musculus (Mouse) spinal cord development [GO:0021510] GO:0005737; GO:0005886; GO:0005923; GO:0021510; GO:0030425; GO:0043025; GO:0043235 42735 XM_029345416.2 2 4 10 10 18 NA NA NA NA NA NA 42736 XR_006396292.1 347 43 109 224 1 NA NA NA NA NA NA 42737 XM_044312359.1 341 154 198 236 245 Q27245 1.73e-133 Putative aminopeptidase W07G4.4 (EC 3.4.11.-) Caenorhabditis elegans proteolysis [GO:0006508] GO:0005737; GO:0006508; GO:0008233; GO:0030145; GO:0070006 42738 XM_029356516.2 378 0 42 170 0 NA NA NA NA NA NA 42739 XM_029340796.2 125 91 74 240 116 O94827 4.71e-86 Pleckstrin homology domain-containing family G member 5 (PH domain-containing family G member 5) (Guanine nucleotide exchange factor 720) (GEF720) Homo sapiens (Human) endothelial cell chemotaxis [GO:0035767]; endothelial cell migration [GO:0043542]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266] GO:0005085; GO:0005737; GO:0005829; GO:0005886; GO:0005911; GO:0007266; GO:0030027; GO:0030139; GO:0030424; GO:0035767; GO:0043123; GO:0043542; GO:0048471; GO:0051056 42740 XM_029338481.2 142 211 116 586 342 Q5TCZ1 2.66e-50 SH3 and PX domain-containing protein 2A (Adapter protein TKS5) (Five SH3 domain-containing protein) (SH3 multiple domains protein 1) (Tyrosine kinase substrate with five SH3 domains) Homo sapiens (Human) in utero embryonic development [GO:0001701]; osteoclast fusion [GO:0072675]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801] GO:0001701; GO:0002020; GO:0002102; GO:0005546; GO:0005737; GO:0005829; GO:0006801; GO:0010314; GO:0016176; GO:0032266; GO:0042554; GO:0042995; GO:0043325; GO:0070161; GO:0070273; GO:0072675 42741 XM_029351152.2 496 167 285 393 737 Q80T21 4.77e-116 ADAMTS-like protein 4 (ADAMTSL-4) (Thrombospondin repeat-containing protein 1) Mus musculus (Mouse) apoptotic process [GO:0006915]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; pigment cell development [GO:0070285]; positive regulation of apoptotic process [GO:0043065] GO:0002020; GO:0002064; GO:0005576; GO:0005614; GO:0006915; GO:0030198; GO:0031012; GO:0042802; GO:0043065; GO:0070285 42742 XM_044329290.1 59 165 180 161 0 NA NA NA NA NA NA 42743 XM_029326121.2 12 0 0 19 5 NA NA NA NA NA NA 42744 XM_044308656.1 36 0 7 50 8 D3YXG0 3.52e-66 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 42745 XM_044308656.1 36 0 7 50 8 D3YXG0 2.89e-51 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 42746 XM_044308656.1 36 0 7 50 8 D3YXG0 2.41e-47 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 42747 XM_044308656.1 36 0 7 50 8 D3YXG0 1.49e-40 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 42748 XM_044308656.1 36 0 7 50 8 D3YXG0 1.87e-40 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 42749 XM_044308656.1 36 0 7 50 8 D3YXG0 1.9e-40 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 42750 XM_044308656.1 36 0 7 50 8 D3YXG0 4.45e-40 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 42751 XM_044308656.1 36 0 7 50 8 D3YXG0 2.44e-39 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 42752 XM_044308656.1 36 0 7 50 8 D3YXG0 4.68e-39 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 42753 XM_044308656.1 36 0 7 50 8 D3YXG0 1.09e-36 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 42754 XM_044308656.1 36 0 7 50 8 D3YXG0 1.35e-36 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 42755 XM_044308656.1 36 0 7 50 8 D3YXG0 1.3e-33 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 42756 XR_006392159.1 46 47 9 300 32 NA NA NA NA NA NA 42757 XM_029358366.2 70 11 15 9 2 NA NA NA NA NA NA 42758 XM_044307438.1 2536 2489 308 396 336 Q8BZM0 1.96e-38 Kelch-like protein 12 (CUL3-interacting protein 1) Mus musculus (Mouse) COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; protein monoubiquitination [GO:0006513]; Wnt signaling pathway [GO:0016055] GO:0006513; GO:0006888; GO:0014029; GO:0014032; GO:0016055; GO:0030127; GO:0030134; GO:0031463; GO:0034451; GO:0042802; GO:0043231; GO:0048208 42759 XM_044314804.1 11 30 35 25 42 NA NA NA NA NA NA 42760 XR_006394930.1 4 49 40 63 112 NA NA NA NA NA NA 42761 XM_029339280.2 79 9 69 30 231 NA NA NA NA NA NA 42762 XM_044316777.1 0 1 6 5 2 NA NA NA NA NA NA 42763 XM_044308510.1 29 0 0 18 3 NA NA NA NA NA NA 42764 XR_006396581.1 4856 3988 1591 200 2840 NA NA NA NA NA NA 42765 XM_044313562.1 286 236 201 375 287 B0S6T2 3.58e-156 Solute carrier family 15 member 2 (Peptide transporter 2) (PEPT2) Danio rerio (Zebrafish) (Brachydanio rerio) dipeptide import across plasma membrane [GO:0140206]; innate immune response [GO:0045087]; peptidoglycan transport [GO:0015835]; protein transport [GO:0015031]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424]; response to yeast [GO:0001878]; transmembrane transport [GO:0055085] GO:0001878; GO:0005886; GO:0015031; GO:0015293; GO:0015835; GO:0016020; GO:0022857; GO:0045087; GO:0055085; GO:0070424; GO:0071916; GO:0140206 42766 XM_029328936.2 75 37 50 83 76 Q13042 0 Cell division cycle protein 16 homolog (Anaphase-promoting complex subunit 6) (APC6) (CDC16 homolog) (CDC16Hs) (Cyclosome subunit 6) Homo sapiens (Human) anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; metaphase/anaphase transition of mitotic cell cycle [GO:0007091]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; protein K11-linked ubiquitination [GO:0070979]; protein ubiquitination [GO:0016567]; regulation of meiotic cell cycle [GO:0051445]; regulation of mitotic cell cycle [GO:0007346] GO:0005654; GO:0005680; GO:0005737; GO:0005813; GO:0005829; GO:0007091; GO:0007346; GO:0016567; GO:0031145; GO:0045842; GO:0051301; GO:0051445; GO:0070979; GO:0072686 42767 XM_044322890.1 827 683 446 749 1072 NA NA NA NA NA NA 42768 XM_029350366.2 3007 3875 2444 2637 1579 NA NA NA NA NA NA 42769 XM_044313257.1 2639 2275 1412 2693 1890 Q5R501 0 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit (DDOST 48 kDa subunit) (Oligosaccharyl transferase 48 kDa subunit) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) protein glycosylation [GO:0006486]; protein N-linked glycosylation via asparagine [GO:0018279] GO:0006486; GO:0008250; GO:0018279 42770 XM_029343604.2 636 128 282 566 1397 Q4R9E0 1.64e-44 Tectonic-3 Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) apoptotic process [GO:0006915]; cilium assembly [GO:0060271]; smoothened signaling pathway [GO:0007224] GO:0006915; GO:0007224; GO:0016020; GO:0060271 42771 XR_003824059.2 3 122 42 45 86 NA NA NA NA NA NA 42772 XR_006394974.1 0 14 0 10 0 NA NA NA NA NA NA 42773 XR_006393129.1 7712 6818 5240 2681 6400 NA NA NA NA NA NA 42774 XM_044312962.1 0 43 16 0 0 NA NA NA NA NA NA 42775 XR_003824051.2 30 14 14 12 20 NA NA NA NA NA NA 42776 XM_029336730.2 78 17 162 166 626 Q61292 1.05e-116 Laminin subunit beta-2 (Laminin-11 subunit beta) (Laminin-14 subunit beta) (Laminin-15 subunit beta) (Laminin-3 subunit beta) (Laminin-4 subunit beta) (Laminin-7 subunit beta) (Laminin-9 subunit beta) (S-laminin subunit beta) (S-LAM beta) Mus musculus (Mouse) animal organ morphogenesis [GO:0009887]; astrocyte development [GO:0014002]; axon extension involved in regeneration [GO:0048677]; axon guidance [GO:0007411]; basement membrane assembly [GO:0070831]; cell migration [GO:0016477]; cell morphogenesis involved in differentiation [GO:0000904]; metanephric glomerular basement membrane development [GO:0072274]; metanephric podocyte development [GO:0072249]; neuromuscular junction development [GO:0007528]; neuron projection development [GO:0031175]; positive regulation of cell adhesion [GO:0045785]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of muscle cell differentiation [GO:0051149]; regulation of basement membrane organization [GO:0110011]; retina development in camera-type eye [GO:0060041]; Schwann cell development [GO:0014044]; substrate adhesion-dependent cell spreading [GO:0034446]; synapse organization [GO:0050808]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0000904; GO:0005178; GO:0005201; GO:0005576; GO:0005604; GO:0005608; GO:0007411; GO:0007528; GO:0007601; GO:0009887; GO:0009888; GO:0014002; GO:0014044; GO:0016477; GO:0031175; GO:0031594; GO:0034446; GO:0043083; GO:0043256; GO:0045202; GO:0045785; GO:0048677; GO:0050808; GO:0051149; GO:0060041; GO:0062023; GO:0070831; GO:0072249; GO:0072274; GO:0098637; GO:0110011; GO:0150043; GO:2001046 42777 XM_044322832.1 0 153 0 0 0 Q5DU56 1.45e-25 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 42778 XM_044322832.1 0 153 0 0 0 Q5DU56 3.79e-22 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 42779 XM_044317243.1 15 3 0 0 32 NA NA NA NA NA NA 42780 XM_044314205.1 597 83 89 221 125 NA NA NA NA NA NA 42781 XM_029342339.2 3381 2497 1903 2218 2541 NA NA NA NA NA NA 42782 XM_044326934.1 16 2 18 1 52 NA NA NA NA NA NA 42783 XM_029357850.2 696 462 582 887 942 A6QLU6 1.41e-74 Adhesion G-protein coupled receptor D1 (G-protein coupled receptor 133) Bos taurus (Bovine) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0005886; GO:0007166; GO:0007186; GO:0007189 42784 XM_044307793.1 10 27 2 3 125 NA NA NA NA NA NA 42785 XM_029331010.2 637 510 397 676 417 Q4R877 4.09e-124 Thiamine transporter 2 (ThTr-2) (ThTr2) (Solute carrier family 19 member 3) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0015234; GO:0016020 42786 XM_044329096.1 75 164 58 44 105 NA NA NA NA NA NA 42787 XR_006393314.1 0 13 3 18 23 NA NA NA NA NA NA 42788 XM_044327938.1 1960 1450 1342 2205 1709 Q7SIA2 0 Bifunctional glutamate/proline--tRNA ligase (Bifunctional aminoacyl-tRNA synthetase) [Includes: Glutamate--tRNA ligase (EC 6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS); Proline--tRNA ligase (EC 6.1.1.15) (Prolyl-tRNA synthetase) (ProRS)] Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) cellular response to insulin stimulus [GO:0032869]; cellular response to type II interferon [GO:0071346]; glutamyl-tRNA aminoacylation [GO:0006424]; negative regulation of translation [GO:0017148]; prolyl-tRNA aminoacylation [GO:0006433]; regulation of long-chain fatty acid import into cell [GO:0140212] GO:0004818; GO:0004827; GO:0005524; GO:0005829; GO:0005886; GO:0006424; GO:0006433; GO:0008270; GO:0017101; GO:0017148; GO:0032869; GO:0035613; GO:0042803; GO:0051020; GO:0071346; GO:0097452; GO:0140212; GO:1990904 42789 XM_044327938.1 1960 1450 1342 2205 1709 Q7SIA2 0 Bifunctional glutamate/proline--tRNA ligase (Bifunctional aminoacyl-tRNA synthetase) [Includes: Glutamate--tRNA ligase (EC 6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS); Proline--tRNA ligase (EC 6.1.1.15) (Prolyl-tRNA synthetase) (ProRS)] Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) cellular response to insulin stimulus [GO:0032869]; cellular response to type II interferon [GO:0071346]; glutamyl-tRNA aminoacylation [GO:0006424]; negative regulation of translation [GO:0017148]; prolyl-tRNA aminoacylation [GO:0006433]; regulation of long-chain fatty acid import into cell [GO:0140212] GO:0004818; GO:0004827; GO:0005524; GO:0005829; GO:0005886; GO:0006424; GO:0006433; GO:0008270; GO:0017101; GO:0017148; GO:0032869; GO:0035613; GO:0042803; GO:0051020; GO:0071346; GO:0097452; GO:0140212; GO:1990904 42790 XM_029332294.2 64 79 11 62 75 Q5R8P3 6.02e-34 Bardet-Biedl syndrome 10 protein homolog Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) chaperone-mediated protein complex assembly [GO:0051131] GO:0005524; GO:0005929; GO:0051131 42791 XM_029329768.2 1358 1114 579 1111 1013 NA NA NA NA NA NA 42792 XM_029338731.2 0 28 0 0 159 Q80TY4 5.29e-56 Suppression of tumorigenicity 18 protein Mus musculus (Mouse) interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6-mediated signaling pathway [GO:0070102]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000122; GO:0000977; GO:0000978; GO:0000981; GO:0003677; GO:0005634; GO:0006357; GO:0008270; GO:0008285; GO:0032993; GO:0033209; GO:0045944; GO:0070102; GO:0070498; GO:2001269 42793 XM_029338731.2 0 28 0 0 159 Q80TY4 9e-34 Suppression of tumorigenicity 18 protein Mus musculus (Mouse) interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6-mediated signaling pathway [GO:0070102]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000122; GO:0000977; GO:0000978; GO:0000981; GO:0003677; GO:0005634; GO:0006357; GO:0008270; GO:0008285; GO:0032993; GO:0033209; GO:0045944; GO:0070102; GO:0070498; GO:2001269 42794 XM_029338731.2 0 28 0 0 159 Q80TY4 7.88e-28 Suppression of tumorigenicity 18 protein Mus musculus (Mouse) interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6-mediated signaling pathway [GO:0070102]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000122; GO:0000977; GO:0000978; GO:0000981; GO:0003677; GO:0005634; GO:0006357; GO:0008270; GO:0008285; GO:0032993; GO:0033209; GO:0045944; GO:0070102; GO:0070498; GO:2001269 42795 XM_044317895.1 2406 3825 1253 2236 1393 O95755 5.85e-78 Ras-related protein Rab-36 Homo sapiens (Human) protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0003924; GO:0005525; GO:0005794; GO:0015031; GO:0016192 42796 XM_029358352.2 74 57 8 107 46 F6S215 5.25e-50 AP-5 complex subunit beta-1 (Adaptor-related protein complex 5 beta subunit) (Beta5) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) endosomal transport [GO:0016197]; protein transport [GO:0015031] GO:0015031; GO:0016197; GO:0030119 42797 XR_006395933.1 26 7 14 7 60 NA NA NA NA NA NA 42798 XR_006397024.1 0 13 7 11 15 NA NA NA NA NA NA 42799 XM_044324683.1 0 0 2 18 0 Q8C0W1 1.81e-61 Ankyrin repeat and MYND domain-containing protein 1 Mus musculus (Mouse) NA GO:0046872 42800 XM_044317336.1 167 110 158 497 126 NA NA NA NA NA NA 42801 XM_044319586.1 0 89 30 175 129 O94762 4.39e-94 ATP-dependent DNA helicase Q5 (EC 3.6.4.12) (DNA helicase, RecQ-like type 5) (RecQ5) (RecQ protein-like 5) Homo sapiens (Human) cell division [GO:0051301]; cellular response to camptothecin [GO:0072757]; cellular response to ketone [GO:1901655]; cellular response to xenobiotic stimulus [GO:0071466]; chromosome separation [GO:0051304]; DNA duplex unwinding [GO:0032508]; DNA metabolic process [GO:0006259]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724]; mitotic cell cycle [GO:0000278]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; negative regulation of transcription elongation by RNA polymerase II [GO:0034244]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414] GO:0000278; GO:0000724; GO:0000993; GO:0003676; GO:0003678; GO:0005524; GO:0005634; GO:0005654; GO:0005694; GO:0005737; GO:0005829; GO:0006259; GO:0006260; GO:0006268; GO:0006281; GO:0006310; GO:0009378; GO:0016591; GO:0016887; GO:0032508; GO:0034244; GO:0042802; GO:0043138; GO:0051301; GO:0051304; GO:0071466; GO:0072757; GO:1901655; GO:1990414; GO:2000042 42802 XM_044319586.1 0 89 30 175 129 O94762 2.8e-35 ATP-dependent DNA helicase Q5 (EC 3.6.4.12) (DNA helicase, RecQ-like type 5) (RecQ5) (RecQ protein-like 5) Homo sapiens (Human) cell division [GO:0051301]; cellular response to camptothecin [GO:0072757]; cellular response to ketone [GO:1901655]; cellular response to xenobiotic stimulus [GO:0071466]; chromosome separation [GO:0051304]; DNA duplex unwinding [GO:0032508]; DNA metabolic process [GO:0006259]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724]; mitotic cell cycle [GO:0000278]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; negative regulation of transcription elongation by RNA polymerase II [GO:0034244]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414] GO:0000278; GO:0000724; GO:0000993; GO:0003676; GO:0003678; GO:0005524; GO:0005634; GO:0005654; GO:0005694; GO:0005737; GO:0005829; GO:0006259; GO:0006260; GO:0006268; GO:0006281; GO:0006310; GO:0009378; GO:0016591; GO:0016887; GO:0032508; GO:0034244; GO:0042802; GO:0043138; GO:0051301; GO:0051304; GO:0071466; GO:0072757; GO:1901655; GO:1990414; GO:2000042 42803 XM_029346237.2 1598 1350 813 1188 1124 P81069 8.83e-62 GA-binding protein subunit beta-2 (GABP subunit beta-2) (GABPB-2) (GA-binding protein beta-2-1) (GABP subunit beta-2-1) (GABPB2-1) Mus musculus (Mouse) positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000976; GO:0005634; GO:0042802; GO:0045944 42804 XR_006391452.1 382 243 333 741 1450 NA NA NA NA NA NA 42805 XM_029324766.2 81 0 53 20 11 Q9H0Z9 1.62e-31 RNA-binding protein 38 (CLL-associated antigen KW-5) (HSRNASEB) (RNA-binding motif protein 38) (RNA-binding region-containing protein 1) (ssDNA-binding protein SEB4) Homo sapiens (Human) 3'-UTR-mediated mRNA stabilization [GO:0070935]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; mRNA processing [GO:0006397]; mRNA stabilization [GO:0048255]; negative regulation of cell population proliferation [GO:0008285]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of cell cycle [GO:0051726]; regulation of myotube differentiation [GO:0010830]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380] GO:0000381; GO:0003723; GO:0003729; GO:0003730; GO:0005634; GO:0005829; GO:0006397; GO:0006977; GO:0006978; GO:0007049; GO:0008285; GO:0008380; GO:0010830; GO:0030154; GO:0043484; GO:0048255; GO:0051726; GO:0070935 42806 XR_006392738.1 63 19 52 43 312 NA NA NA NA NA NA 42807 XM_044320527.1 230 1524 353 1281 553 NA NA NA NA NA NA 42808 XR_006398066.1 11 1 1 14 0 NA NA NA NA NA NA 42809 XR_006392285.1 16 0 11 0 35 NA NA NA NA NA NA 42810 XR_003825016.2 82 56 56 69 89 NA NA NA NA NA NA 42811 XM_029357136.2 23 56 7 33 21 NA NA NA NA NA NA 42812 XM_044327055.1 16 3 0 59 0 NA NA NA NA NA NA 42813 XM_044311403.1 22 21 30 6 40 NA NA NA NA NA NA 42814 XR_003824759.2 0 13 16 20 14 NA NA NA NA NA NA 42815 XM_029328885.2 150 149 66 175 180 Q9H4B4 1.59e-148 Serine/threonine-protein kinase PLK3 (EC 2.7.11.21) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) (Polo-like kinase 3) (PLK-3) (Proliferation-related kinase) Homo sapiens (Human) apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cytoplasmic microtubule organization [GO:0031122]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endomitotic cell cycle [GO:0007113]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; Golgi disassembly [GO:0090166]; mitotic cell cycle [GO:0000278]; mitotic G1/S transition checkpoint signaling [GO:0044819]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of chaperone-mediated autophagy [GO:1904716]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia [GO:2000777]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; regulation of cell division [GO:0051302]; regulation of cytokinesis [GO:0032465]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to osmotic stress [GO:0006970]; response to radiation [GO:0009314]; response to reactive oxygen species [GO:0000302] GO:0000082; GO:0000086; GO:0000122; GO:0000278; GO:0000302; GO:0000922; GO:0002039; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005795; GO:0005813; GO:0006468; GO:0006915; GO:0006970; GO:0006974; GO:0006977; GO:0007113; GO:0009314; GO:0030425; GO:0031122; GO:0032465; GO:0043025; GO:0043066; GO:0043491; GO:0044819; GO:0051302; GO:0090166; GO:0090316; GO:0106310; GO:1901796; GO:1904716; GO:2000777 42816 XM_029332957.2 1297 812 812 1104 1361 Q9V3D2 6.23e-162 Oxygen-dependent coproporphyrinogen-III oxidase (COX) (Coprogen oxidase) (Coproporphyrinogenase) (EC 1.3.3.3) Drosophila melanogaster (Fruit fly) heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782] GO:0004109; GO:0005737; GO:0005739; GO:0005758; GO:0006782; GO:0006783; GO:0042803 42817 XM_029329378.2 761 497 386 609 589 NA NA NA NA NA NA 42818 XM_044323298.1 0 0 5 0 14 Q5R5U3 9.02e-79 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 42819 XM_044323298.1 0 0 5 0 14 Q5R5U3 1.85e-75 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 42820 XM_044323298.1 0 0 5 0 14 Q5R5U3 1.95e-75 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 42821 XM_044323298.1 0 0 5 0 14 Q5R5U3 2.3e-75 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 42822 XM_044323298.1 0 0 5 0 14 Q5R5U3 5.83e-75 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 42823 XM_044323298.1 0 0 5 0 14 Q5R5U3 9.38e-74 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 42824 XM_044323298.1 0 0 5 0 14 Q5R5U3 3.25e-73 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 42825 XM_044323298.1 0 0 5 0 14 Q5R5U3 4.08e-71 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 42826 XM_044323298.1 0 0 5 0 14 Q5R5U3 6.27e-67 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 42827 XM_044323298.1 0 0 5 0 14 Q5R5U3 1.06e-64 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 42828 XM_029344137.2 244 205 64 223 81 Q6NS52 0 Diacylglycerol kinase beta (DAG kinase beta) (EC 2.7.1.107) (Diglyceride kinase beta) (DGK-beta) Mus musculus (Mouse) diacylglycerol metabolic process [GO:0046339]; glycerolipid metabolic process [GO:0046486]; intracellular signal transduction [GO:0035556]; lipid phosphorylation [GO:0046834]; modulation of chemical synaptic transmission [GO:0050804]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidic acid metabolic process [GO:0046473]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; regulation of postsynapse organization [GO:0099175]; response to bacterium [GO:0009617] GO:0004143; GO:0005509; GO:0005524; GO:0005829; GO:0005886; GO:0006654; GO:0007205; GO:0008289; GO:0009617; GO:0016020; GO:0035556; GO:0046339; GO:0046473; GO:0046486; GO:0046834; GO:0050804; GO:0098685; GO:0098978; GO:0099147; GO:0099175 42829 XM_044318303.1 195 324 180 348 252 NA NA NA NA NA NA 42830 XM_044312418.1 0 4 15 34 27 NA NA NA NA NA NA 42831 XM_044322538.1 2308 3221 1010 1829 336 Q8BHP7 1.45e-42 Olfactomedin-like protein 2A (Photomedin-1) Mus musculus (Mouse) extracellular matrix organization [GO:0030198]; signal transduction [GO:0007165] GO:0005615; GO:0007165; GO:0030198; GO:0031012; GO:0042802; GO:0050840 42832 XM_044326452.1 0 0 0 0 6 P18130 3.79e-26 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) Bos taurus (Bovine) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of vasoconstriction [GO:0045907]; regulation of cardiac muscle contraction [GO:0055117] GO:0001996; GO:0004930; GO:0004937; GO:0005634; GO:0005737; GO:0005886; GO:0005901; GO:0007200; GO:0007204; GO:0007267; GO:0031965; GO:0043410; GO:0045907; GO:0046982; GO:0055117; GO:0071880 42833 XM_029347963.2 81 0 42 0 464 NA NA NA NA NA NA 42834 XM_044317743.1 152 263 58 152 134 Q08DY9 1.15e-35 Caspase-3 (CASP-3) (EC 3.4.22.56) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12] Bos taurus (Bovine) positive regulation of amyloid-beta formation [GO:1902004]; proteolysis [GO:0006508]; regulation of protein stability [GO:0031647] GO:0004175; GO:0005737; GO:0006508; GO:0031647; GO:0097153; GO:0097199; GO:0097200; GO:1902004 42835 XM_029323895.2 144 150 39 23 79 Q7CS13 2.77e-50 Deacetylase Atu3266 (EC 3.1.1.-) Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58)) NA GO:0016810; GO:0019213; GO:0046872 42836 XM_029343087.2 701 631 476 805 901 Q9D0R4 0 Probable ATP-dependent RNA helicase DDX56 (EC 3.6.4.13) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD box protein 56) Mus musculus (Mouse) defense response to virus [GO:0051607]; modulation by host of viral RNA genome replication [GO:0044830]; positive regulation of neuron projection development [GO:0010976]; rRNA processing [GO:0006364] GO:0003724; GO:0005524; GO:0005730; GO:0005829; GO:0006364; GO:0010976; GO:0016887; GO:0035613; GO:0044830; GO:0051607 42837 XM_044318823.1 0 0 69 0 2 Q8IVV2 2.17e-84 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 42838 XM_044318823.1 0 0 69 0 2 Q8IVV2 2.27e-83 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 42839 XM_044318823.1 0 0 69 0 2 Q8IVV2 5.77e-80 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 42840 XM_044318823.1 0 0 69 0 2 Q8IVV2 2.28e-78 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 42841 XM_044318823.1 0 0 69 0 2 Q8IVV2 1.8e-65 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 42842 XM_044318823.1 0 0 69 0 2 Q8IVV2 1.31e-63 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 42843 XM_044318823.1 0 0 69 0 2 Q8IVV2 4.27e-61 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 42844 XM_044318823.1 0 0 69 0 2 Q8IVV2 2.49e-46 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 42845 XM_029329196.2 0 0 13 10 0 A5WUL3 3.1e-60 Mediator of RNA polymerase II transcription subunit 22 (Mediator complex subunit 22) (Surfeit locus protein 5) Danio rerio (Zebrafish) (Brachydanio rerio) regulation of transcription by RNA polymerase II [GO:0006357] GO:0003712; GO:0006357; GO:0016592 42846 XM_029339939.2 392 213 90 356 301 Q09081 3.62e-89 Potassium voltage-gated channel subfamily A member 2 (KC22) (Voltage-gated potassium channel subunit Kv1.2) Oryctolagus cuniculus (Rabbit) neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233] GO:0005249; GO:0005251; GO:0005789; GO:0005886; GO:0008076; GO:0014059; GO:0019228; GO:0019233; GO:0021633; GO:0030027; GO:0030424; GO:0030425; GO:0031258; GO:0032809; GO:0033010; GO:0034765; GO:0042734; GO:0043194; GO:0043204; GO:0043679; GO:0044224; GO:0045188; GO:0051260; GO:0071805 42847 XM_044328839.1 0 1 0 0 14 NA NA NA NA NA NA 42848 XM_044324975.1 329 163 194 168 232 O77636 2.42e-143 Disintegrin and metalloproteinase domain-containing protein 17 (ADAM 17) (EC 3.4.24.86) (TNF-alpha convertase) (TNF-alpha-converting enzyme) (CD antigen CD156b) Sus scrofa (Pig) membrane protein ectodomain proteolysis [GO:0006509]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; proteolysis [GO:0006508]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0004175; GO:0004222; GO:0005112; GO:0005886; GO:0006508; GO:0006509; GO:0007219; GO:0007220; GO:0033209; GO:0046872; GO:0070374 42849 XM_044325483.1 156 88 73 129 191 Q5UQ13 4.62e-25 Collagen-like protein 2 Acanthamoeba polyphaga mimivirus (APMV) NA GO:0044423 42850 XM_044325483.1 156 88 73 129 191 Q5UQ13 2.26e-22 Collagen-like protein 2 Acanthamoeba polyphaga mimivirus (APMV) NA GO:0044423 42851 XM_044325483.1 156 88 73 129 191 Q5UQ13 1.5e-21 Collagen-like protein 2 Acanthamoeba polyphaga mimivirus (APMV) NA GO:0044423 42852 XM_044325483.1 156 88 73 129 191 Q5UQ13 2.26e-21 Collagen-like protein 2 Acanthamoeba polyphaga mimivirus (APMV) NA GO:0044423 42853 XM_044325483.1 156 88 73 129 191 Q5UQ13 3e-21 Collagen-like protein 2 Acanthamoeba polyphaga mimivirus (APMV) NA GO:0044423 42854 XM_044325483.1 156 88 73 129 191 Q5UQ13 3.41e-21 Collagen-like protein 2 Acanthamoeba polyphaga mimivirus (APMV) NA GO:0044423 42855 XM_044325483.1 156 88 73 129 191 Q5UQ13 4.7e-21 Collagen-like protein 2 Acanthamoeba polyphaga mimivirus (APMV) NA GO:0044423 42856 XM_044325483.1 156 88 73 129 191 Q5UQ13 8.37e-21 Collagen-like protein 2 Acanthamoeba polyphaga mimivirus (APMV) NA GO:0044423 42857 XM_029352017.2 3228 4954 5140 7210 6612 Q95218 5.89e-110 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 42858 XM_029352017.2 3228 4954 5140 7210 6612 Q95218 5.01e-103 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 42859 XM_029352017.2 3228 4954 5140 7210 6612 Q95218 1.51e-80 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 42860 XM_029352017.2 3228 4954 5140 7210 6612 Q95218 2.97e-37 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 42861 XM_044317930.1 26 1 14 15 100 NA NA NA NA NA NA 42862 XM_044322768.1 3139 2971 3697 1456 1050 Q3TZZ7 2.27e-120 Extended synaptotagmin-2 (E-Syt2) Mus musculus (Mouse) endocytosis [GO:0006897]; endoplasmic reticulum-plasma membrane tethering [GO:0061817]; lipid transport [GO:0006869] GO:0005509; GO:0005544; GO:0005789; GO:0005829; GO:0005886; GO:0006869; GO:0006897; GO:0008429; GO:0031210; GO:0031234; GO:0035091; GO:0042802; GO:0044232; GO:0061817; GO:0140268 42863 XM_044322768.1 3139 2971 3697 1456 1050 Q3TZZ7 7.03e-30 Extended synaptotagmin-2 (E-Syt2) Mus musculus (Mouse) endocytosis [GO:0006897]; endoplasmic reticulum-plasma membrane tethering [GO:0061817]; lipid transport [GO:0006869] GO:0005509; GO:0005544; GO:0005789; GO:0005829; GO:0005886; GO:0006869; GO:0006897; GO:0008429; GO:0031210; GO:0031234; GO:0035091; GO:0042802; GO:0044232; GO:0061817; GO:0140268 42864 XM_029351915.2 48 38 26 33 63 Q5U374 1.66e-41 Kelch-like protein 12 Danio rerio (Zebrafish) (Brachydanio rerio) anterior/posterior pattern specification [GO:0009952]; convergent extension involved in axis elongation [GO:0060028]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; protein monoubiquitination [GO:0006513]; Wnt signaling pathway [GO:0016055] GO:0006513; GO:0006888; GO:0009952; GO:0014029; GO:0014032; GO:0016055; GO:0030127; GO:0030134; GO:0031463; GO:0048208; GO:0060028 42865 XM_029342772.2 482 393 163 415 456 Q16629 8.78e-26 Serine/arginine-rich splicing factor 7 (Splicing factor 9G8) (Splicing factor, arginine/serine-rich 7) Homo sapiens (Human) cellular response to leukemia inhibitory factor [GO:1990830]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; RNA splicing [GO:0008380] GO:0000398; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006397; GO:0008270; GO:0008380; GO:0016607; GO:0019904; GO:0048025; GO:0051028; GO:0070062; GO:1990830 42866 XR_006397761.1 7 15 4 68 43 NA NA NA NA NA NA 42867 XM_044319919.1 103 33 63 87 27 Q5R478 1.88e-157 AP-3 complex subunit mu-1 (AP-3 adaptor complex mu3A subunit) (Adaptor-related protein complex 3 subunit mu-1) (Mu-adaptin 3A) (Mu3A-adaptin) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192] GO:0005794; GO:0006886; GO:0008089; GO:0016192; GO:0030131; GO:0030659; GO:0031267; GO:0048490; GO:1904115 42868 XM_029342881.2 1181 801 669 1626 1053 NA NA NA NA NA NA 42869 XM_029335520.2 517 551 300 480 455 Q61035 0 Histidine--tRNA ligase, cytoplasmic (EC 6.1.1.21) (Histidyl-tRNA synthetase) (HisRS) Mus musculus (Mouse) histidyl-tRNA aminoacylation [GO:0006427]; mitochondrial translation [GO:0032543] GO:0004821; GO:0005524; GO:0005737; GO:0005739; GO:0005829; GO:0006427; GO:0032543; GO:0042802; GO:0042803 42870 XM_029348972.2 135 96 69 127 169 Q7ZW24 0 GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase (EC 2.4.1.131) (Asparagine-linked glycosylation protein 11 homolog) (Glycolipid 2-alpha-mannosyltransferase) Danio rerio (Zebrafish) (Brachydanio rerio) oligosaccharide-lipid intermediate biosynthetic process [GO:0006490]; protein N-linked glycosylation [GO:0006487] GO:0004377; GO:0005789; GO:0006487; GO:0006490; GO:0016020 42871 XM_029340992.2 24 132 61 74 126 Q8K078 2.3e-117 Solute carrier organic anion transporter family member 4A1 (Organic anion-transporting polypeptide E) (OATP-E) (Sodium-independent organic anion transporter E) (Solute carrier family 21 member 12) Mus musculus (Mouse) sodium-independent organic anion transport [GO:0043252]; thyroid hormone metabolic process [GO:0042403] GO:0005886; GO:0008514; GO:0015132; GO:0015347; GO:0015349; GO:0042403; GO:0043252 42872 XM_044318759.1 30 0 17 4 83 NA NA NA NA NA NA 42873 XM_029355782.2 0 46 8 204 0 Q9EQD2 3.47e-35 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 42874 XM_029340050.2 31 3 2 5 5 NA NA NA NA NA NA 42875 XM_044322140.1 44 0 24 41 49 NA NA NA NA NA NA 42876 XM_044322906.1 723 533 975 625 1680 Q5ZL23 3.8e-66 Amyloid beta A4 precursor protein-binding family B member 1-interacting protein (APBB1-interacting protein 1) Gallus gallus (Chicken) signal transduction [GO:0007165] GO:0005829; GO:0005856; GO:0005886; GO:0007165 42877 XM_044316788.1 237 1031 235 1418 892 Q61824 2.23e-128 Disintegrin and metalloproteinase domain-containing protein 12 (ADAM 12) (EC 3.4.24.-) (Meltrin-alpha) Mus musculus (Mouse) cell adhesion [GO:0007155]; positive regulation of angiogenesis [GO:0045766]; proteolysis [GO:0006508] GO:0004222; GO:0005654; GO:0005886; GO:0006508; GO:0007155; GO:0017124; GO:0045766; GO:0046872 42878 XM_044314934.1 40 8 5 5 16 NA NA NA NA NA NA 42879 XM_029343623.2 58 124 117 255 96 A9Y006 2.25e-77 Aquaporin-3 (Aquaglyceroporin-3) Sus scrofa (Pig) glycerol transmembrane transport [GO:0015793]; polyol transmembrane transport [GO:0015791]; water transport [GO:0006833] GO:0005886; GO:0006833; GO:0015166; GO:0015204; GO:0015250; GO:0015254; GO:0015791; GO:0015793; GO:0016323 42880 XM_029329331.2 265 283 162 262 264 Q5ZHN9 1.38e-138 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial (EC 2.7.8.5) (Phosphatidylglycerophosphate synthase 1) (PGP synthase 1) Gallus gallus (Chicken) cardiolipin biosynthetic process [GO:0032049] GO:0005524; GO:0005739; GO:0008444; GO:0032049 42881 XM_044324771.1 159 291 208 212 185 G3V9H8 2.94e-84 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Rattus norvegicus (Rat) cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0007156; GO:0007158; GO:0007169; GO:0007399; GO:0009410; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030182; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0098797 42882 XM_029339453.2 59 73 59 22 76 NA NA NA NA NA NA 42883 XM_029357075.2 46 30 31 69 65 Q9H5K3 1.1e-91 Protein O-mannose kinase (POMK) (EC 2.7.1.183) (Protein kinase-like protein SgK196) (Sugen kinase 196) Homo sapiens (Human) brain development [GO:0007420]; carbohydrate phosphorylation [GO:0046835]; learning or memory [GO:0007611]; neuromuscular process [GO:0050905]; protein O-linked glycosylation [GO:0006493]; protein phosphorylation [GO:0006468]; sensory perception of pain [GO:0019233] GO:0004672; GO:0005524; GO:0005789; GO:0006468; GO:0006493; GO:0007420; GO:0007611; GO:0016773; GO:0019200; GO:0019233; GO:0046835; GO:0050905 42884 XR_006394360.1 2 244 51 36 80 NA NA NA NA NA NA 42885 XM_044322819.1 21 0 12 2 0 NA NA NA NA NA NA 42886 XR_006393586.1 14 0 0 1 0 NA NA NA NA NA NA 42887 XM_044321837.1 26 164 175 131 184 Q9XTR8 3.05e-33 Lipase ZK262.3 (EC 3.1.1.-) Caenorhabditis elegans lipid catabolic process [GO:0016042] GO:0005576; GO:0016042; GO:0016787 42888 XM_044315223.1 1108 1163 553 632 676 Q6NY52 1.96e-151 THO complex subunit 5 homolog Danio rerio (Zebrafish) (Brachydanio rerio) cell differentiation [GO:0030154]; mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; RNA splicing [GO:0008380] GO:0000445; GO:0003729; GO:0005737; GO:0006397; GO:0006406; GO:0008380; GO:0016607; GO:0030154; GO:0032786 42889 XM_044308049.1 251 17 0 0 0 Q9QUM7 0 MutS protein homolog 5 Mus musculus (Mouse) chiasma assembly [GO:0051026]; female gamete generation [GO:0007292]; homologous chromosome pairing at meiosis [GO:0007129]; meiosis I [GO:0007127]; mismatch repair [GO:0006298] GO:0000795; GO:0003690; GO:0005524; GO:0005634; GO:0005654; GO:0006298; GO:0007127; GO:0007129; GO:0007292; GO:0030983; GO:0051026; GO:0140664 42890 XR_006395930.1 0 14 42 50 42 NA NA NA NA NA NA 42891 XR_006391989.1 54 0 16 36 0 NA NA NA NA NA NA 42892 XM_044317817.1 0 0 0 5 23 NA NA NA NA NA NA 42893 XM_044323601.1 767 516 634 824 884 B8JK39 4.46e-105 Integrin alpha-9 Mus musculus (Mouse) cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; neutrophil chemotaxis [GO:0030593]; wound healing [GO:0042060] GO:0005178; GO:0005518; GO:0007155; GO:0007160; GO:0007229; GO:0008305; GO:0009897; GO:0009925; GO:0016020; GO:0030593; GO:0033627; GO:0034679; GO:0042060; GO:0043236; GO:0046872; GO:0050900; GO:0098609 42894 XM_044320825.1 68 101 43 77 110 NA NA NA NA NA NA 42895 XR_006393626.1 1522 1510 1077 1354 1735 NA NA NA NA NA NA 42896 XR_006392436.1 9 7 18 9 77 NA NA NA NA NA NA 42897 XM_029355597.2 0 123 148 0 123 O15439 0 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 42898 XM_044321999.1 0 0 43 0 0 A2VDD2 2.02e-22 Dynein light chain Tctex-type 5-B (Tctex1 domain-containing protein 1-B) Xenopus laevis (African clawed frog) NA NA 42899 XM_044318406.1 6 0 23 25 0 NA NA NA NA NA NA 42900 XM_029329745.2 1260 1461 927 1009 946 Q9CPX6 5.36e-142 Ubiquitin-like-conjugating enzyme ATG3 (EC 2.3.2.-) (Autophagy-related protein 3) (APG3-like) Mus musculus (Mouse) autophagosome assembly [GO:0000045]; autophagy of mitochondrion [GO:0000422]; autophagy of nucleus [GO:0044804]; macroautophagy [GO:0016236]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; negative regulation of phagocytosis [GO:0050765]; protein modification process [GO:0036211]; protein transport [GO:0015031]; protein ubiquitination [GO:0016567]; regulation of cilium assembly [GO:1902017] GO:0000045; GO:0000153; GO:0000422; GO:0005829; GO:0015031; GO:0016236; GO:0016567; GO:0019776; GO:0019777; GO:0019787; GO:0019899; GO:0036211; GO:0043653; GO:0044804; GO:0050765; GO:1902017 42901 XM_044325455.1 204 14 52 2 79 P19217 2.59e-55 Sulfotransferase 1E1 (ST1E1) (EC 2.8.2.4) (Estrogen sulfotransferase) (Sulfotransferase, estrogen-preferring) Bos taurus (Bovine) estrogen metabolic process [GO:0008210]; sulfation [GO:0051923] GO:0004062; GO:0004304; GO:0005496; GO:0005737; GO:0005829; GO:0008146; GO:0008210; GO:0050294; GO:0051923 42902 XM_029355862.2 1039 634 516 815 1123 Q5R7R9 0 SNW domain-containing protein 1 (Nuclear protein SkiP) (Ski-interacting protein) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of neurogenesis [GO:0050769]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of vitamin D receptor signaling pathway [GO:0070562]; retinoic acid receptor signaling pathway [GO:0048384] GO:0000122; GO:0000398; GO:0003713; GO:0003714; GO:0005634; GO:0016363; GO:0016922; GO:0030511; GO:0042771; GO:0042809; GO:0042974; GO:0045944; GO:0046332; GO:0048026; GO:0048384; GO:0048385; GO:0050769; GO:0051571; GO:0070562; GO:0071007 42903 XM_029333632.2 0 0 0 50 229 P53349 8.74e-117 Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1) Mus musculus (Mouse) apoptotic mitochondrial changes [GO:0008637]; camera-type eye development [GO:0043010]; epithelial cell morphogenesis [GO:0003382]; eyelid development in camera-type eye [GO:0061029]; JNK cascade [GO:0007254]; MAPK cascade [GO:0000165]; morphogenesis of an epithelial sheet [GO:0002011]; negative regulation of actin filament bundle assembly [GO:0032232]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of viral transcription [GO:0050434]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein polyubiquitination [GO:0000209]; regulation of cell migration [GO:0030334]; response to osmotic stress [GO:0006970]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ubiquitin-dependent protein catabolic process [GO:0006511]; wound healing [GO:0042060] GO:0000165; GO:0000209; GO:0002011; GO:0003382; GO:0004672; GO:0004674; GO:0004706; GO:0004708; GO:0004709; GO:0004842; GO:0005524; GO:0005737; GO:0005829; GO:0005856; GO:0006468; GO:0006511; GO:0006970; GO:0007179; GO:0007254; GO:0008092; GO:0008270; GO:0008432; GO:0008637; GO:0016020; GO:0018105; GO:0019901; GO:0030054; GO:0030334; GO:0030838; GO:0031434; GO:0031941; GO:0032232; GO:0042060; GO:0043010; GO:0043065; GO:0043406; GO:0043410; GO:0043507; GO:0044877; GO:0045893; GO:0045944; GO:0046330; GO:0046625; GO:0046777; GO:0050434; GO:0051019; GO:0061029; GO:0090263; GO:0106310 42904 XM_029333632.2 0 0 0 50 229 P53349 3.23e-112 Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1) Mus musculus (Mouse) apoptotic mitochondrial changes [GO:0008637]; camera-type eye development [GO:0043010]; epithelial cell morphogenesis [GO:0003382]; eyelid development in camera-type eye [GO:0061029]; JNK cascade [GO:0007254]; MAPK cascade [GO:0000165]; morphogenesis of an epithelial sheet [GO:0002011]; negative regulation of actin filament bundle assembly [GO:0032232]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of viral transcription [GO:0050434]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein polyubiquitination [GO:0000209]; regulation of cell migration [GO:0030334]; response to osmotic stress [GO:0006970]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ubiquitin-dependent protein catabolic process [GO:0006511]; wound healing [GO:0042060] GO:0000165; GO:0000209; GO:0002011; GO:0003382; GO:0004672; GO:0004674; GO:0004706; GO:0004708; GO:0004709; GO:0004842; GO:0005524; GO:0005737; GO:0005829; GO:0005856; GO:0006468; GO:0006511; GO:0006970; GO:0007179; GO:0007254; GO:0008092; GO:0008270; GO:0008432; GO:0008637; GO:0016020; GO:0018105; GO:0019901; GO:0030054; GO:0030334; GO:0030838; GO:0031434; GO:0031941; GO:0032232; GO:0042060; GO:0043010; GO:0043065; GO:0043406; GO:0043410; GO:0043507; GO:0044877; GO:0045893; GO:0045944; GO:0046330; GO:0046625; GO:0046777; GO:0050434; GO:0051019; GO:0061029; GO:0090263; GO:0106310 42905 XM_029336017.2 2875 2284 1077 1051 1564 Q8K4D3 1.5e-23 Proton-coupled amino acid transporter 1 (Proton/amino acid transporter 1) (Solute carrier family 36 member 1) Mus musculus (Mouse) alanine transport [GO:0032328]; amino acid import across plasma membrane [GO:0089718]; amino acid transmembrane transport [GO:0003333]; glycine transport [GO:0015816]; L-alanine transport [GO:0015808]; neutral amino acid transport [GO:0015804]; proline transmembrane transport [GO:0035524]; proline transport [GO:0015824]; proton transmembrane transport [GO:1902600]; taurine transport [GO:0015734] GO:0003333; GO:0005280; GO:0005297; GO:0005368; GO:0005764; GO:0005765; GO:0005783; GO:0005886; GO:0015078; GO:0015175; GO:0015179; GO:0015180; GO:0015187; GO:0015193; GO:0015734; GO:0015804; GO:0015808; GO:0015816; GO:0015824; GO:0016324; GO:0022858; GO:0032328; GO:0035524; GO:0089718; GO:1902600 42906 XR_006395441.1 10 20 10 0 12 NA NA NA NA NA NA 42907 XM_029343080.2 7 0 4 5 2 P49286 2.97e-31 Melatonin receptor type 1B (Mel-1B-R) (Mel1b receptor) Homo sapiens (Human) camera-type eye development [GO:0043010]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; glucose homeostasis [GO:0042593]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of insulin secretion [GO:0046676]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transmission of nerve impulse [GO:0051970]; negative regulation of vasoconstriction [GO:0045906]; positive regulation of circadian sleep/wake cycle, non-REM sleep [GO:0046010]; positive regulation of transmission of nerve impulse [GO:0051971]; regulation of insulin secretion [GO:0050796]; regulation of neuronal action potential [GO:0098908] GO:0004930; GO:0005886; GO:0007186; GO:0007187; GO:0007268; GO:0008502; GO:0010754; GO:0042593; GO:0043010; GO:0043524; GO:0045202; GO:0045906; GO:0046010; GO:0046676; GO:0050796; GO:0051481; GO:0051970; GO:0051971; GO:0098908; GO:1902260 42908 XM_029348719.2 427 385 241 290 405 Q6AYE3 5.04e-135 Transcriptional adapter 2-alpha (Transcriptional adapter 2-like) (ADA2-like protein) Rattus norvegicus (Rat) chromatin remodeling [GO:0006338]; histone H3 acetylation [GO:0043966]; histone H3-K14 acetylation [GO:0044154]; mitotic cell cycle [GO:0000278]; positive regulation of histone acetylation [GO:0035066]; regulation of cell cycle [GO:0051726]; regulation of cell division [GO:0051302]; regulation of DNA-templated transcription [GO:0006355]; regulation of embryonic development [GO:0045995]; regulation of histone deacetylation [GO:0031063]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tubulin deacetylation [GO:0090043] GO:0000124; GO:0000278; GO:0001932; GO:0003677; GO:0003682; GO:0003713; GO:0005634; GO:0006338; GO:0006355; GO:0006357; GO:0008270; GO:0031063; GO:0031647; GO:0035066; GO:0043966; GO:0044154; GO:0045995; GO:0051302; GO:0051726; GO:0070461; GO:0072686; GO:0090043; GO:0140672 42909 XR_003822984.1 2 15 175 17 20 NA NA NA NA NA NA 42910 XM_029345787.2 0 102 0 114 0 NA NA NA NA NA NA 42911 XM_029342383.2 5 0 2 0 25 O43422 1.29e-30 52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (Death-associated protein 4) (THAP domain-containing protein 0) (THAP domain-containing protein 12) Homo sapiens (Human) negative regulation of cell population proliferation [GO:0008285]; signal transduction [GO:0007165] GO:0003677; GO:0005634; GO:0007165; GO:0008285; GO:0046872; GO:0046983 42912 XM_029329811.2 0 0 0 0 98 NA NA NA NA NA NA 42913 XM_029337256.2 15 46 14 87 30 F4KFT7 1.94e-23 Bifunctional TH2 protein, mitochondrial (THIAMINE REQUIRING 2) [Includes: Thiamine phosphate phosphatase (EC 3.1.3.100); Aminopyrimidine aminohydrolase (EC 3.5.99.2)] Arabidopsis thaliana (Mouse-ear cress) thiamine biosynthetic process [GO:0009228] GO:0005739; GO:0005829; GO:0009228; GO:0042131; GO:0050334 42914 XM_029334578.2 7 0 12 8 10 NA NA NA NA NA NA 42915 XR_006395447.1 13 0 17 5 108 NA NA NA NA NA NA 42916 XM_029332395.2 464 365 180 506 395 O35435 1.79e-144 Dihydroorotate dehydrogenase (quinone), mitochondrial (DHOdehase) (EC 1.3.5.2) (Dihydroorotate oxidase) Mus musculus (Mouse) 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; positive regulation of apoptotic process [GO:0043065]; pyrimidine ribonucleotide biosynthetic process [GO:0009220]; regulation of mitochondrial fission [GO:0090140]; UDP biosynthetic process [GO:0006225] GO:0004151; GO:0004152; GO:0005654; GO:0005739; GO:0005743; GO:0005829; GO:0006207; GO:0006225; GO:0009220; GO:0010181; GO:0043025; GO:0043065; GO:0044205; GO:0048038; GO:0048039; GO:0090140; GO:0106430 42917 XM_029347897.2 0 36 12 0 59 Q9H6E4 6.31e-37 Coiled-coil domain-containing protein 134 Homo sapiens (Human) angiogenesis [GO:0001525]; embryonic hemopoiesis [GO:0035162]; embryonic liver development [GO:1990402]; placenta development [GO:0001890]; regulation of ossification [GO:0030278]; ventricular system development [GO:0021591] GO:0001525; GO:0001890; GO:0005576; GO:0005634; GO:0005783; GO:0016020; GO:0021591; GO:0030278; GO:0035162; GO:1990402 42918 XM_029352073.2 0 28 3 5 34 NA NA NA NA NA NA 42919 XM_029338798.2 0 0 0 0 140 P55214 7.63e-55 Caspase-7 (CASP-7) (EC 3.4.22.60) (Apoptotic protease Mch-3) (ICE-like apoptotic protease 3) (ICE-LAP3) (SREBP cleavage activity 2) (SCA-2) [Cleaved into: Caspase-7 subunit p20; Caspase-7 subunit p11] Mesocricetus auratus (Golden hamster) defense response to bacterium [GO:0042742]; intracellular signal transduction [GO:0035556]; lymphocyte apoptotic process [GO:0070227]; positive regulation of plasma membrane repair [GO:1905686]; proteolysis [GO:0006508] GO:0003723; GO:0004190; GO:0005615; GO:0005634; GO:0005737; GO:0005829; GO:0006508; GO:0035556; GO:0042742; GO:0070227; GO:0097153; GO:1905686 42920 XM_044316037.1 376 20 30 18 140 NA NA NA NA NA NA 42921 XM_044322307.1 0 0 0 1 7 NA NA NA NA NA NA 42922 XM_029333856.2 801 597 257 586 420 Q9UPM9 5.07e-96 B9 domain-containing protein 1 (MKS1-related protein 1) Homo sapiens (Human) camera-type eye development [GO:0043010]; cilium assembly [GO:0060271]; embryonic digit morphogenesis [GO:0042733]; in utero embryonic development [GO:0001701]; neuroepithelial cell differentiation [GO:0060563]; regulation of protein localization [GO:0032880]; smoothened signaling pathway [GO:0007224]; vasculature development [GO:0001944] GO:0001701; GO:0001944; GO:0005813; GO:0005829; GO:0007224; GO:0008158; GO:0016020; GO:0032880; GO:0035869; GO:0036038; GO:0036064; GO:0042733; GO:0043010; GO:0060271; GO:0060563 42923 XM_029340658.2 345 148 268 228 206 Q9Y6H5 1.63e-30 Synphilin-1 (Sph1) (Alpha-synuclein-interacting protein) Homo sapiens (Human) cell death [GO:0008219]; dopamine metabolic process [GO:0042417]; regulation of inclusion body assembly [GO:0090083]; regulation of neurotransmitter secretion [GO:0046928] GO:0005654; GO:0005737; GO:0005829; GO:0008021; GO:0008219; GO:0031625; GO:0036464; GO:0042417; GO:0042734; GO:0042802; GO:0043025; GO:0046928; GO:0090083 42924 XM_029323507.2 257 182 87 203 346 P24861 7.2e-121 G2/mitotic-specific cyclin-A Patella vulgata (Common limpet) cell division [GO:0051301]; mitotic cell cycle phase transition [GO:0044772] GO:0016538; GO:0044772; GO:0051301 42925 XM_044309324.1 43 14 23 86 93 NA NA NA NA NA NA 42926 XM_044313357.1 222 169 37 198 279 Q96RW7 8.83e-26 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 42927 XM_044313357.1 222 169 37 198 279 Q96RW7 1.07e-24 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 42928 XM_044313357.1 222 169 37 198 279 Q96RW7 2.8e-24 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 42929 XM_044313357.1 222 169 37 198 279 Q96RW7 1.73e-23 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 42930 XM_044313357.1 222 169 37 198 279 Q96RW7 4.63e-22 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 42931 XM_044323871.1 0 0 9 0 14 NA NA NA NA NA NA 42932 XM_029338825.2 11 15 5 9 3 NA NA NA NA NA NA 42933 XR_006392707.1 130 163 105 112 239 NA NA NA NA NA NA 42934 XM_044318757.1 0 0 5 22 40 NA NA NA NA NA NA 42935 XM_044310410.1 156 63 67 159 274 Q95SX7 1.57e-25 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 42936 XM_029329844.2 462 269 252 309 381 Q5U374 1.39e-66 Kelch-like protein 12 Danio rerio (Zebrafish) (Brachydanio rerio) anterior/posterior pattern specification [GO:0009952]; convergent extension involved in axis elongation [GO:0060028]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; protein monoubiquitination [GO:0006513]; Wnt signaling pathway [GO:0016055] GO:0006513; GO:0006888; GO:0009952; GO:0014029; GO:0014032; GO:0016055; GO:0030127; GO:0030134; GO:0031463; GO:0048208; GO:0060028 42937 XM_029330169.2 235 89 99 158 152 NA NA NA NA NA NA 42938 XM_029324803.2 1239 426 356 447 473 NA NA NA NA NA NA 42939 XR_006391462.1 34 3 0 7 24 NA NA NA NA NA NA 42940 XM_044317047.1 147 135 75 226 165 Q4QRH7 3.26e-84 Peroxisomal membrane protein PEX16 (Peroxin-16) (Peroxisomal biogenesis factor 16) Danio rerio (Zebrafish) (Brachydanio rerio) peroxisome organization [GO:0007031] GO:0005778; GO:0007031 42941 XM_029344027.2 1871 798 354 2384 724 Q9BXB1 4.23e-122 Leucine-rich repeat-containing G-protein coupled receptor 4 (G-protein coupled receptor 48) Homo sapiens (Human) bone mineralization [GO:0030282]; bone remodeling [GO:0046849]; canonical Wnt signaling pathway involved in metanephric kidney development [GO:0061290]; cell differentiation involved in metanephros development [GO:0072202]; circadian regulation of gene expression [GO:0032922]; digestive tract development [GO:0048565]; epithelial cell proliferation involved in renal tubule morphogenesis [GO:2001013]; hair follicle development [GO:0001942]; innate immune response [GO:0045087]; intestinal stem cell homeostasis [GO:0036335]; male genitalia development [GO:0030539]; metanephric glomerulus development [GO:0072224]; metanephric nephron tubule morphogenesis [GO:0072282]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of cytokine production [GO:0001818]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; osteoblast differentiation [GO:0001649]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of DNA-templated transcription [GO:0045893]; spermatogenesis [GO:0007283] GO:0001649; GO:0001818; GO:0001942; GO:0004888; GO:0004930; GO:0005886; GO:0007283; GO:0016500; GO:0030282; GO:0030539; GO:0032922; GO:0034122; GO:0036335; GO:0045087; GO:0045892; GO:0045893; GO:0046849; GO:0048565; GO:0061290; GO:0072202; GO:0072224; GO:0072282; GO:0090190; GO:0090263; GO:0120163; GO:2001013 42942 XM_044315473.1 43 13 23 36 5 NA NA NA NA NA NA 42943 XM_044327476.1 20 27 61 88 37 NA NA NA NA NA NA 42944 XM_029334220.2 51 29 23 53 131 Q503V9 2.82e-27 Uridylate-specific endoribonuclease B (EC 4.6.1.-) (Protein endoU-B) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0003723; GO:0004521; GO:0016829; GO:0046872 42945 XR_006395320.1 0 99 5 50 6 NA NA NA NA NA NA 42946 XM_029344744.2 50 0 50 0 94 NA NA NA NA NA NA 42947 XM_029335246.2 37 16 31 86 55 Q92051 7.38e-51 Carbonic anhydrase (EC 4.2.1.1) (Carbonate dehydratase) Danio rerio (Zebrafish) (Brachydanio rerio) carbon dioxide transport [GO:0015670]; hypotonic salinity response [GO:0042539]; one-carbon metabolic process [GO:0006730] GO:0004089; GO:0005737; GO:0006730; GO:0008270; GO:0015670; GO:0016836; GO:0042539 42948 XM_029343712.2 92 52 93 101 117 NA NA NA NA NA NA 42949 XM_029330787.2 94 272 211 176 293 Q15650 1.52e-146 Activating signal cointegrator 1 (ASC-1) (Thyroid receptor-interacting protein 4) (TR-interacting protein 4) (TRIP-4) Homo sapiens (Human) intracellular estrogen receptor signaling pathway [GO:0030520]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA-templated transcription [GO:0006355]; regulation of myoblast differentiation [GO:0045661]; rescue of stalled ribosome [GO:0072344]; ribosome disassembly [GO:0032790]; ribosome-associated ubiquitin-dependent protein catabolic process [GO:1990116]; toxin transport [GO:1901998] GO:0002020; GO:0003713; GO:0005634; GO:0005654; GO:0005737; GO:0005815; GO:0005829; GO:0006355; GO:0008270; GO:0016604; GO:0016922; GO:0019901; GO:0030331; GO:0030520; GO:0031594; GO:0032790; GO:0032991; GO:0035035; GO:0044389; GO:0045661; GO:0045893; GO:0072344; GO:0099053; GO:1901998; GO:1990116 42950 XM_029324810.2 4155 1694 1443 5049 4090 NA NA NA NA NA NA 42951 XM_044315649.1 0 0 86 0 0 NA NA NA NA NA NA 42952 XM_044322913.1 904 163 200 659 874 Q5NU32 4.64e-85 Amine oxidase [flavin-containing] A (EC 1.4.3.21) (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A) Equus caballus (Horse) catecholamine metabolic process [GO:0006584]; neurotransmitter catabolic process [GO:0042135] GO:0005739; GO:0005741; GO:0006584; GO:0008131; GO:0042135; GO:0050660; GO:0052595; GO:0052596; GO:0097621 42953 XM_029348847.2 1497 1337 731 1177 862 A7SXZ6 0 Probable tRNA N6-adenosine threonylcarbamoyltransferase (EC 2.3.1.234) (N6-L-threonylcarbamoyladenine synthase) (t(6)A synthase) (t(6)A37 threonylcarbamoyladenosine biosynthesis protein osgep) (tRNA threonylcarbamoyladenosine biosynthesis protein osgep) Nematostella vectensis (Starlet sea anemone) tRNA threonylcarbamoyladenosine modification [GO:0002949] GO:0000408; GO:0002949; GO:0005634; GO:0005737; GO:0046872; GO:0061711 42954 XM_044319874.1 850 499 451 752 843 Q5EAC2 1.26e-131 Glutathione synthetase (GSH synthetase) (GSH-S) (EC 6.3.2.3) (Glutathione synthase) Bos taurus (Bovine) NA GO:0000287; GO:0004363; GO:0005524; GO:0042803; GO:0043295 42955 XM_044318824.1 678 870 1560 2600 2572 C8YR32 5.14e-65 Lipoxygenase homology domain-containing protein 1 Mus musculus (Mouse) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 42956 XM_044318824.1 678 870 1560 2600 2572 C8YR32 1.57e-64 Lipoxygenase homology domain-containing protein 1 Mus musculus (Mouse) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 42957 XM_044318824.1 678 870 1560 2600 2572 C8YR32 2.01e-59 Lipoxygenase homology domain-containing protein 1 Mus musculus (Mouse) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 42958 XM_044318824.1 678 870 1560 2600 2572 C8YR32 5.23e-59 Lipoxygenase homology domain-containing protein 1 Mus musculus (Mouse) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 42959 XM_044318824.1 678 870 1560 2600 2572 C8YR32 1.72e-57 Lipoxygenase homology domain-containing protein 1 Mus musculus (Mouse) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 42960 XM_044318824.1 678 870 1560 2600 2572 C8YR32 2.27e-51 Lipoxygenase homology domain-containing protein 1 Mus musculus (Mouse) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 42961 XM_044318824.1 678 870 1560 2600 2572 C8YR32 2.02e-48 Lipoxygenase homology domain-containing protein 1 Mus musculus (Mouse) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 42962 XM_044318824.1 678 870 1560 2600 2572 C8YR32 5.53e-46 Lipoxygenase homology domain-containing protein 1 Mus musculus (Mouse) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 42963 XM_044318824.1 678 870 1560 2600 2572 C8YR32 1.14e-41 Lipoxygenase homology domain-containing protein 1 Mus musculus (Mouse) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 42964 XM_044318824.1 678 870 1560 2600 2572 C8YR32 1.83e-41 Lipoxygenase homology domain-containing protein 1 Mus musculus (Mouse) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 42965 XM_044318824.1 678 870 1560 2600 2572 C8YR32 1.26e-37 Lipoxygenase homology domain-containing protein 1 Mus musculus (Mouse) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 42966 XR_006396918.1 289 251 264 652 763 NA NA NA NA NA NA 42967 XM_029346981.2 385 360 90 494 455 Q6P2X9 5.68e-41 Monocarboxylate transporter 12 (MCT 12) (Solute carrier family 16 member 12) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) creatine transmembrane transport [GO:0015881]; creatinine metabolic process [GO:0046449] GO:0005308; GO:0005886; GO:0015292; GO:0015881; GO:0016323; GO:0046449 42968 XM_029356211.2 1143 455 710 544 804 Q8R367 8.72e-31 Ras-related and estrogen-regulated growth inhibitor (EC 3.6.5.2) Mus musculus (Mouse) negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; Ras protein signal transduction [GO:0007265]; response to hormone [GO:0009725] GO:0001650; GO:0003924; GO:0003925; GO:0005525; GO:0005634; GO:0005654; GO:0005829; GO:0005886; GO:0007265; GO:0008285; GO:0009725; GO:0019003; GO:0030308 42969 XR_006392445.1 0 29 6 0 10 Q8VD65 8.34e-43 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) Mus musculus (Mouse) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016236; GO:0016241; GO:0030242; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 42970 XM_044314743.1 0 114 62 0 0 NA NA NA NA NA NA 42971 XM_029356349.2 0 0 0 0 102 P69478 5.04e-40 Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4S-1) (C4ST-1) (C4ST1) Rattus norvegicus (Rat) apoptotic process [GO:0006915]; carbohydrate biosynthetic process [GO:0016051]; cartilage development [GO:0051216]; chondrocyte development [GO:0002063]; chondroitin sulfate biosynthetic process [GO:0030206]; chondroitin sulfate metabolic process [GO:0030204]; developmental growth [GO:0048589]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; embryonic viscerocranium morphogenesis [GO:0048703]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; polysaccharide localization [GO:0033037]; post-anal tail morphogenesis [GO:0036342]; post-embryonic development [GO:0009791]; proteoglycan biosynthetic process [GO:0030166]; regulation of cell population proliferation [GO:0042127]; respiratory gaseous exchange by respiratory system [GO:0007585]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0000139; GO:0001537; GO:0001701; GO:0002063; GO:0006915; GO:0007179; GO:0007585; GO:0008146; GO:0009791; GO:0016051; GO:0030166; GO:0030204; GO:0030206; GO:0030326; GO:0030512; GO:0033037; GO:0036342; GO:0042127; GO:0042733; GO:0043066; GO:0047756; GO:0048589; GO:0048703; GO:0048704; GO:0050659; GO:0051216 42972 XM_044326533.1 32 7 0 0 0 NA NA NA NA NA NA 42973 XM_029339753.2 307 153 128 149 282 Q767K8 3.04e-26 28S ribosomal protein S18b, mitochondrial (MRP-S18-b) (Mrps18-b) (S18mt-b) (28S ribosomal protein S18-2, mitochondrial) (MRP-S18-2) Sus scrofa (Pig) mitochondrial translation [GO:0032543] GO:0003735; GO:0005654; GO:0005739; GO:0005763; GO:0030054; GO:0032543 42974 XM_044326545.1 31 2 29 70 34 NA NA NA NA NA NA 42975 XR_006397518.1 188 126 105 100 260 NA NA NA NA NA NA 42976 XM_044313123.1 180 248 237 286 312 NA NA NA NA NA NA 42977 XM_044320224.1 82 0 21 119 62 Q5M9N0 7.42e-29 Coiled-coil domain-containing protein 158 Homo sapiens (Human) NA NA 42978 XM_029338489.2 117 101 39 236 130 Q5RAR0 2.96e-124 Translation initiation factor eIF-2B subunit alpha (eIF-2B GDP-GTP exchange factor subunit alpha) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003743 42979 XM_029348843.2 0 55 0 32 0 Q9FWW9 1.64e-64 Flavin-containing monooxygenase FMO GS-OX-like 2 (EC 1.8.-.-) (Flavin-monooxygenase glucosinolate S-oxygenase-like 2) Arabidopsis thaliana (Mouse-ear cress) defense response to fungus [GO:0050832] GO:0004499; GO:0050660; GO:0050661; GO:0050832 42980 XM_029331319.2 9 0 18 98 73 Q9I8C7 1.01e-87 Neuronal acetylcholine receptor subunit alpha-10 (Alpha 10 nAChR) (Nicotinic acetylcholine receptor subunit alpha-10) (NACHR alpha-10) Gallus gallus (Chicken) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; response to auditory stimulus [GO:0010996]; signal transduction [GO:0007165] GO:0004888; GO:0005231; GO:0005262; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0010996; GO:0022848; GO:0030594; GO:0034220; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051899; GO:1904315 42981 XM_029349533.2 351 68 128 279 159 A7SXG9 2.97e-38 Nematocyst expressed protein 8 (NEP-8) (NEP8) Nematostella vectensis (Starlet sea anemone) NA GO:0005576; GO:0042151; GO:0090729 42982 XM_044311303.1 492 749 340 682 685 Q91W78 9.37e-39 U6 snRNA phosphodiesterase 1 (3'-5' RNA exonuclease USB1) (EC 4.6.1.-) Mus musculus (Mouse) RNA splicing [GO:0008380]; snRNA 3'-end processing [GO:0034472]; U6 snRNA 3'-end processing [GO:0034477] GO:0000175; GO:0005634; GO:0005654; GO:0008380; GO:0016829; GO:0034472; GO:0034477; GO:0045171; GO:1990838 42983 XM_029339168.2 342 0 99 144 36 Q5VTY9 5.89e-54 Protein-cysteine N-palmitoyltransferase HHAT (EC 2.3.1.-) (Hedgehog acyltransferase) (Melanoma antigen recognized by T-cells 2) (MART-2) (Skinny hedgehog protein 1) Homo sapiens (Human) N-terminal peptidyl-L-cysteine N-palmitoylation [GO:0018009]; protein palmitoylation [GO:0018345]; smoothened signaling pathway [GO:0007224] GO:0000139; GO:0005525; GO:0005783; GO:0005789; GO:0005794; GO:0007224; GO:0008374; GO:0016409; GO:0016746; GO:0018009; GO:0018345 42984 XM_029326497.2 21 26 30 5 33 F1R6N4 3.86e-64 Ethylmalonyl-CoA decarboxylase (EC 4.1.1.94) (Enoyl-CoA hydratase domain-containing protein 1) (Methylmalonyl-CoA decarboxylase) (MMCD) Danio rerio (Zebrafish) (Brachydanio rerio) fatty acid beta-oxidation [GO:0006635] GO:0004492; GO:0005829; GO:0006635; GO:0016831 42985 XR_006397261.1 16 3 4 36 0 NA NA NA NA NA NA 42986 XM_044323131.1 32 16 0 155 40 Q29496 2.12e-106 Cytochrome P450 3A24 (EC 1.14.14.1) (CYPIIIA24) Ovis aries (Sheep) NA GO:0004497; GO:0005506; GO:0005789; GO:0020037; GO:0070330 42987 XM_044328093.1 31 7 39 59 110 NA NA NA NA NA NA 42988 XM_044326742.1 186 29 113 135 6 NA NA NA NA NA NA 42989 XM_029346467.2 924 643 406 665 511 Q1L8G7 1.31e-48 GATA zinc finger domain-containing protein 1 Danio rerio (Zebrafish) (Brachydanio rerio) chromatin organization [GO:0006325]; regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006325; GO:0006355; GO:0031674; GO:0043565; GO:0046872 42990 XM_029350686.2 1113 258 305 764 200 NA NA NA NA NA NA 42991 XM_029327300.2 26 0 8 7 71 NA NA NA NA NA NA 42992 XM_044327382.1 7 45 20 39 69 Q5DU56 1.78e-32 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 42993 XM_044327382.1 7 45 20 39 69 Q5DU56 6.06e-30 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 42994 XM_044327382.1 7 45 20 39 69 Q5DU56 1.1e-29 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 42995 XM_044327382.1 7 45 20 39 69 Q5DU56 5.09e-26 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 42996 XM_044327382.1 7 45 20 39 69 Q5DU56 1.05e-23 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 42997 XM_029337254.2 730 544 265 737 481 F4KFT7 1.68e-23 Bifunctional TH2 protein, mitochondrial (THIAMINE REQUIRING 2) [Includes: Thiamine phosphate phosphatase (EC 3.1.3.100); Aminopyrimidine aminohydrolase (EC 3.5.99.2)] Arabidopsis thaliana (Mouse-ear cress) thiamine biosynthetic process [GO:0009228] GO:0005739; GO:0005829; GO:0009228; GO:0042131; GO:0050334 42998 XM_044325916.1 2 9 2 2 31 NA NA NA NA NA NA 42999 XM_044309026.1 69 46 47 72 124 P49642 1.29e-157 DNA primase small subunit (EC 2.7.7.102) (DNA primase 49 kDa subunit) (p49) Homo sapiens (Human) DNA replication initiation [GO:0006270]; DNA replication, synthesis of RNA primer [GO:0006269] GO:0000287; GO:0003896; GO:0005654; GO:0005658; GO:0006269; GO:0006270; GO:0008270; GO:0016020; GO:0032553 43000 XM_044313313.1 305 153 178 206 174 Q4VBI7 2.2e-116 Syntaxin-18 Danio rerio (Zebrafish) (Brachydanio rerio) intracellular protein transport [GO:0006886]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] GO:0005484; GO:0005783; GO:0005789; GO:0006886; GO:0006890; GO:0031201 43001 XM_044309528.1 2578 1802 1642 3034 2820 Q8BX70 0 Intermembrane lipid transfer protein VPS13C (Vacuolar protein sorting-associated protein 13C) Mus musculus (Mouse) lipid transport [GO:0006869]; mitochondrion organization [GO:0007005]; negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:1905090]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]; response to insulin [GO:0032868] GO:0005741; GO:0005764; GO:0005765; GO:0005770; GO:0005789; GO:0005811; GO:0005829; GO:0006623; GO:0006869; GO:0007005; GO:0019898; GO:0031902; GO:0032127; GO:0032868; GO:0045053; GO:1905090 43002 XM_044309528.1 2578 1802 1642 3034 2820 Q8BX70 2.24e-66 Intermembrane lipid transfer protein VPS13C (Vacuolar protein sorting-associated protein 13C) Mus musculus (Mouse) lipid transport [GO:0006869]; mitochondrion organization [GO:0007005]; negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:1905090]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]; response to insulin [GO:0032868] GO:0005741; GO:0005764; GO:0005765; GO:0005770; GO:0005789; GO:0005811; GO:0005829; GO:0006623; GO:0006869; GO:0007005; GO:0019898; GO:0031902; GO:0032127; GO:0032868; GO:0045053; GO:1905090 43003 XM_044309528.1 2578 1802 1642 3034 2820 Q8BX70 1.19e-34 Intermembrane lipid transfer protein VPS13C (Vacuolar protein sorting-associated protein 13C) Mus musculus (Mouse) lipid transport [GO:0006869]; mitochondrion organization [GO:0007005]; negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:1905090]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]; response to insulin [GO:0032868] GO:0005741; GO:0005764; GO:0005765; GO:0005770; GO:0005789; GO:0005811; GO:0005829; GO:0006623; GO:0006869; GO:0007005; GO:0019898; GO:0031902; GO:0032127; GO:0032868; GO:0045053; GO:1905090 43004 XM_029337319.2 0 0 113 0 95 Q1LZI2 1.71e-48 Putative thiamine transporter SLC35F3 (Solute carrier family 35 member F3) Mus musculus (Mouse) thiamine transport [GO:0015888] GO:0015888; GO:0016020 43005 XM_044307548.1 796 636 379 912 658 Q502W6 0 von Willebrand factor A domain-containing protein 3B (VWA domain-containing protein 3B) Homo sapiens (Human) NA GO:0005654; GO:0005829 43006 XM_029344002.2 795 810 611 638 365 Q8QGQ6 1.29e-64 Circadian locomoter output cycles protein kaput Gallus gallus (Chicken) cellular response to DNA damage stimulus [GO:0006974]; circadian regulation of gene expression [GO:0032922]; protein acetylation [GO:0006473]; regulation of transcription by RNA polymerase II [GO:0006357]; response to redox state [GO:0051775] GO:0000978; GO:0000981; GO:0003677; GO:0005634; GO:0005829; GO:0006357; GO:0006473; GO:0006974; GO:0032922; GO:0046983; GO:0051775; GO:0070888; GO:1990513 43007 XM_044320128.1 0 1 4 0 51 B8V7S0 0 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 43008 XM_029350170.2 964 894 784 1881 1312 Q9H8H3 3.67e-52 Putative methyltransferase-like protein 7A (EC 2.1.1.-) (Protein AAM-B) Homo sapiens (Human) methylation [GO:0032259] GO:0005576; GO:0005783; GO:0005811; GO:0008168; GO:0016020; GO:0032259; GO:1904724 43009 XM_029357561.2 53 99 86 154 178 NA NA NA NA NA NA 43010 XM_044317735.1 624 385 192 363 448 Q7Z569 0 BRCA1-associated protein (EC 2.3.2.27) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (RING-type E3 ubiquitin transferase BRAP2) (Renal carcinoma antigen NY-REN-63) Homo sapiens (Human) MAPK cascade [GO:0000165]; negative regulation of signal transduction [GO:0009968]; protein ubiquitination [GO:0016567]; Ras protein signal transduction [GO:0007265] GO:0000151; GO:0000165; GO:0003676; GO:0004842; GO:0005654; GO:0005737; GO:0005829; GO:0007265; GO:0008139; GO:0008270; GO:0009968; GO:0016567; GO:0031965; GO:0042802; GO:0061630 43011 XM_044318073.1 169 159 91 205 155 Q498E6 3.1e-59 N-lysine methyltransferase KMT5A-B (EC 2.1.1.-) (Histone-lysine N-methyltransferase KMT5A-B) (EC 2.1.1.361) (Lysine-specific methylase 5A-B) (Mitotic phosphoprotein 36) (SET domain-containing protein 8-B) Xenopus laevis (African clawed frog) cell cycle [GO:0007049]; cell division [GO:0051301]; chromatin organization [GO:0006325] GO:0005634; GO:0005694; GO:0006325; GO:0007049; GO:0018024; GO:0051301; GO:0140944 43012 XM_029327700.2 3 7 9 24 16 NA NA NA NA NA NA 43013 XM_029339085.2 73 38 97 129 363 Q5T2R2 1.43e-124 All trans-polyprenyl-diphosphate synthase PDSS1 (All-trans-decaprenyl-diphosphate synthase subunit 1) (EC 2.5.1.91) (Decaprenyl pyrophosphate synthase subunit 1) (Decaprenyl-diphosphate synthase subunit 1) (Solanesyl-diphosphate synthase subunit 1) (Trans-prenyltransferase 1) (TPT 1) Homo sapiens (Human) isoprenoid biosynthetic process [GO:0008299]; ubiquinone biosynthetic process [GO:0006744] GO:0000010; GO:0004659; GO:0005759; GO:0006744; GO:0008299; GO:0046872; GO:0046982; GO:0052923; GO:0097269; GO:1990234 43014 XM_044313672.1 226 116 113 188 178 NA NA NA NA NA NA 43015 XM_029336993.2 215 166 165 277 337 NA NA NA NA NA NA 43016 XR_006397800.1 604 723 178 539 533 NA NA NA NA NA NA 43017 XM_044327983.1 42 0 22 3 15 NA NA NA NA NA NA 43018 XM_029330275.2 0 35 23 14 0 O42574 1.07e-35 Beta-1 adrenergic receptor (Beta-1 adrenoreceptor) (Beta-1 adrenoceptor) (x-BETA1AR) Xenopus laevis (African clawed frog) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; positive regulation of GTPase activity [GO:0043547]; positive regulation of heart contraction [GO:0045823] GO:0004940; GO:0005085; GO:0005769; GO:0005886; GO:0043547; GO:0045823; GO:0071880 43019 XM_044320298.1 210 119 135 339 246 NA NA NA NA NA NA 43020 XR_006397940.1 83 149 121 144 123 NA NA NA NA NA NA 43021 XM_029348835.2 954 879 430 1501 1063 Q9NRH2 4.48e-141 SNF-related serine/threonine-protein kinase (EC 2.7.11.1) (SNF1-related kinase) Homo sapiens (Human) intracellular signal transduction [GO:0035556]; myeloid cell differentiation [GO:0030099]; protein phosphorylation [GO:0006468] GO:0000287; GO:0004674; GO:0005524; GO:0005634; GO:0006468; GO:0030099; GO:0035556; GO:0106310 43022 XM_029328558.2 21 5 4 25 5 NA NA NA NA NA NA 43023 XM_029356624.2 0 36 14 42 86 NA NA NA NA NA NA 43024 XM_044314450.1 808 812 408 522 344 P15374 3.4e-91 Ubiquitin carboxyl-terminal hydrolase isozyme L3 (UCH-L3) (EC 3.4.19.12) (Ubiquitin thioesterase L3) Homo sapiens (Human) post-translational protein modification [GO:0043687]; protein catabolic process [GO:0030163]; protein deubiquitination [GO:0016579]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004843; GO:0005654; GO:0005737; GO:0005829; GO:0006511; GO:0008233; GO:0016567; GO:0016579; GO:0019784; GO:0030163; GO:0043130; GO:0043687 43025 XM_044309939.1 932 235 403 729 638 A7MBJ4 1.15e-37 Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) Bos taurus (Bovine) cell migration [GO:0016477]; negative regulation of receptor binding [GO:1900121]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; synaptic membrane adhesion [GO:0099560] GO:0004725; GO:0006470; GO:0008201; GO:0016020; GO:0016477; GO:0035335; GO:0099560; GO:1900121 43026 XM_044309939.1 932 235 403 729 638 A7MBJ4 7.05e-32 Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) Bos taurus (Bovine) cell migration [GO:0016477]; negative regulation of receptor binding [GO:1900121]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; synaptic membrane adhesion [GO:0099560] GO:0004725; GO:0006470; GO:0008201; GO:0016020; GO:0016477; GO:0035335; GO:0099560; GO:1900121 43027 XM_044309939.1 932 235 403 729 638 A7MBJ4 2.7e-28 Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) Bos taurus (Bovine) cell migration [GO:0016477]; negative regulation of receptor binding [GO:1900121]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; synaptic membrane adhesion [GO:0099560] GO:0004725; GO:0006470; GO:0008201; GO:0016020; GO:0016477; GO:0035335; GO:0099560; GO:1900121 43028 XM_044309939.1 932 235 403 729 638 A7MBJ4 1.27e-27 Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) Bos taurus (Bovine) cell migration [GO:0016477]; negative regulation of receptor binding [GO:1900121]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; synaptic membrane adhesion [GO:0099560] GO:0004725; GO:0006470; GO:0008201; GO:0016020; GO:0016477; GO:0035335; GO:0099560; GO:1900121 43029 XM_044309939.1 932 235 403 729 638 A7MBJ4 5.88e-25 Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) Bos taurus (Bovine) cell migration [GO:0016477]; negative regulation of receptor binding [GO:1900121]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; synaptic membrane adhesion [GO:0099560] GO:0004725; GO:0006470; GO:0008201; GO:0016020; GO:0016477; GO:0035335; GO:0099560; GO:1900121 43030 XM_044309939.1 932 235 403 729 638 A7MBJ4 1.41e-23 Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) Bos taurus (Bovine) cell migration [GO:0016477]; negative regulation of receptor binding [GO:1900121]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; synaptic membrane adhesion [GO:0099560] GO:0004725; GO:0006470; GO:0008201; GO:0016020; GO:0016477; GO:0035335; GO:0099560; GO:1900121 43031 XM_044325404.1 47 64 42 43 32 NA NA NA NA NA NA 43032 XR_003824487.2 19 2 33 3 138 NA NA NA NA NA NA 43033 XM_044317459.1 22 3 1 7 5 O62852 9.74e-42 Short transient receptor potential channel 5 (Rtrp5) (TrpC5) (Capacitative calcium entry channel 2) (CCE2) Oryctolagus cuniculus (Rabbit) neuron apoptotic process [GO:0051402]; phosphatidylserine exposure on apoptotic cell surface [GO:0070782] GO:0005262; GO:0005886; GO:0034704; GO:0051402; GO:0070679; GO:0070782 43034 XM_044311008.1 0 0 11 0 0 NA NA NA NA NA NA 43035 XM_044307119.1 0 0 0 0 15 Q9U6Y6 3.54e-108 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 43036 XM_029355857.2 686 393 398 515 561 A4IG59 1.14e-105 WASH complex subunit 1 (WAS protein family homolog 1) Danio rerio (Zebrafish) (Brachydanio rerio) Arp2/3 complex-mediated actin nucleation [GO:0034314]; endocytic recycling [GO:0032456]; endosomal transport [GO:0016197]; exocytosis [GO:0006887]; protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147] GO:0003779; GO:0005769; GO:0005829; GO:0006887; GO:0015031; GO:0016197; GO:0031901; GO:0032456; GO:0034314; GO:0042147; GO:0043014; GO:0043015; GO:0055037; GO:0055038; GO:0071203 43037 XM_029356768.2 1755 1257 964 1384 1522 Q9ES00 0 Ubiquitin conjugation factor E4 B (EC 2.3.2.27) (RING-type E3 ubiquitin transferase E4 B) (Ubiquitin fusion degradation protein 2) Mus musculus (Mouse) granzyme-mediated apoptotic signaling pathway [GO:0008626]; neuron projection development [GO:0031175]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein folding [GO:0006457]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; response to endoplasmic reticulum stress [GO:0034976]; response to UV [GO:0009411]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; ventricular trabecula myocardium morphogenesis [GO:0003222] GO:0000151; GO:0000209; GO:0003222; GO:0005524; GO:0005634; GO:0005737; GO:0006457; GO:0006511; GO:0006513; GO:0008626; GO:0009411; GO:0016567; GO:0019899; GO:0030163; GO:0030433; GO:0031175; GO:0034450; GO:0034976; GO:0043161; GO:0051082; GO:0051117; GO:0051865; GO:0061630 43038 XM_044328175.1 1875 490 644 1675 69 P50430 2.18e-131 Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S) Rattus norvegicus (Rat) anterior head development [GO:0097065]; autophagy [GO:0006914]; central nervous system development [GO:0007417]; colon epithelial cell migration [GO:0061580]; dermatan sulfate catabolic process [GO:0030209]; positive regulation of neuron projection development [GO:0010976]; regulation of epithelial cell migration [GO:0010632]; response to estrogen [GO:0043627]; response to methylmercury [GO:0051597]; response to nutrient [GO:0007584]; response to pH [GO:0009268] GO:0003943; GO:0004065; GO:0005739; GO:0005764; GO:0005791; GO:0005794; GO:0006914; GO:0007417; GO:0007584; GO:0008484; GO:0009268; GO:0009986; GO:0010632; GO:0010976; GO:0030209; GO:0043627; GO:0043890; GO:0046872; GO:0051597; GO:0061580; GO:0097065 43039 XM_029352330.2 1177 725 1837 1637 1726 O60673 0 DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Protein reversionless 3-like) (REV3-like) (hREV3) Homo sapiens (Human) DNA-templated DNA replication [GO:0006261]; double-strand break repair via homologous recombination [GO:0000724]; error-prone translesion synthesis [GO:0042276] GO:0000166; GO:0000724; GO:0003677; GO:0003887; GO:0005634; GO:0005654; GO:0005730; GO:0006261; GO:0016035; GO:0042276; GO:0046872; GO:0051539 43040 XM_029352330.2 1177 725 1837 1637 1726 O60673 5.18e-98 DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Protein reversionless 3-like) (REV3-like) (hREV3) Homo sapiens (Human) DNA-templated DNA replication [GO:0006261]; double-strand break repair via homologous recombination [GO:0000724]; error-prone translesion synthesis [GO:0042276] GO:0000166; GO:0000724; GO:0003677; GO:0003887; GO:0005634; GO:0005654; GO:0005730; GO:0006261; GO:0016035; GO:0042276; GO:0046872; GO:0051539 43041 XR_006393221.1 91 108 109 179 170 NA NA NA NA NA NA 43042 XM_044312154.1 2 4 9 15 13 NA NA NA NA NA NA 43043 XM_029357613.2 1870 2027 1267 1193 922 Q6DJF8 2.92e-73 Histone-arginine methyltransferase METTL23 (EC 2.1.1.319) (Methyltransferase-like protein 23) Xenopus laevis (African clawed frog) chromatin organization [GO:0006325]; histone H3-R17 methylation [GO:0034971] GO:0005634; GO:0005737; GO:0006325; GO:0034971; GO:0035242; GO:0035642 43044 XM_044313720.1 167 102 128 78 65 NA NA NA NA NA NA 43045 XR_006396315.1 11 5 20 16 20 NA NA NA NA NA NA 43046 XR_003827128.2 0 0 0 9 12 NA NA NA NA NA NA 43047 XM_044309926.1 14 9 1 15 39 NA NA NA NA NA NA 43048 XM_044323780.1 738 473 486 904 824 A2ARA8 2.33e-62 Integrin alpha-8 [Cleaved into: Integrin alpha-8 heavy chain; Integrin alpha-8 light chain] Mus musculus (Mouse) brain development [GO:0007420]; cell adhesion mediated by integrin [GO:0033627]; cell projection organization [GO:0030030]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; establishment of protein localization [GO:0045184]; extracellular matrix organization [GO:0030198]; inner ear morphogenesis [GO:0042472]; integrin-mediated signaling pathway [GO:0007229]; kidney development [GO:0001822]; memory [GO:0007613]; mesodermal cell differentiation [GO:0048333]; metanephros development [GO:0001656]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; smooth muscle cell differentiation [GO:0051145]; smooth muscle tissue development [GO:0048745]; substrate adhesion-dependent cell spreading [GO:0034446]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001656; GO:0001822; GO:0005178; GO:0005783; GO:0005886; GO:0007160; GO:0007179; GO:0007229; GO:0007420; GO:0007613; GO:0008305; GO:0009897; GO:0009986; GO:0014069; GO:0030030; GO:0030198; GO:0030511; GO:0032591; GO:0033627; GO:0034446; GO:0042472; GO:0043204; GO:0045177; GO:0045184; GO:0045944; GO:0046872; GO:0048333; GO:0048745; GO:0051145; GO:0098609; GO:0098839; GO:0098978 43049 XR_006395048.1 123 16 27 60 0 P55024 6.13e-91 Tyrosinase (EC 1.14.18.1) (Monophenol monooxygenase) Gallus gallus (Chicken) melanin biosynthetic process [GO:0042438]; response to blue light [GO:0009637] GO:0004503; GO:0009637; GO:0033162; GO:0042438; GO:0042470; GO:0046872 43050 XR_006395048.1 123 16 27 60 0 P55024 6.13e-91 Tyrosinase (EC 1.14.18.1) (Monophenol monooxygenase) Gallus gallus (Chicken) melanin biosynthetic process [GO:0042438]; response to blue light [GO:0009637] GO:0004503; GO:0009637; GO:0033162; GO:0042438; GO:0042470; GO:0046872 43051 XR_006395048.1 123 16 27 60 0 P55024 6.13e-91 Tyrosinase (EC 1.14.18.1) (Monophenol monooxygenase) Gallus gallus (Chicken) melanin biosynthetic process [GO:0042438]; response to blue light [GO:0009637] GO:0004503; GO:0009637; GO:0033162; GO:0042438; GO:0042470; GO:0046872 43052 XR_003826516.2 121 123 139 234 317 NA NA NA NA NA NA 43053 XM_029349667.2 307 261 77 318 333 P46850 2.89e-171 RNA-splicing ligase RtcB (EC 6.5.1.8) (3'-phosphate/5'-hydroxy nucleic acid ligase) Escherichia coli (strain K12) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; RNA processing [GO:0006396]; RNA repair [GO:0042245]; tRNA processing [GO:0008033] GO:0003909; GO:0005525; GO:0006281; GO:0006396; GO:0006974; GO:0008033; GO:0008452; GO:0030145; GO:0042245 43054 XR_006395504.1 115 1671 529 659 1081 NA NA NA NA NA NA 43055 XM_029356572.2 0 82 20 30 34 NA NA NA NA NA NA 43056 XM_029343324.2 16 3 5 2 11 Q6P9K9 2.8e-30 Neurexin-3 (Neurexin III-alpha) (Neurexin-3-alpha) Mus musculus (Mouse) adult behavior [GO:0030534]; cell adhesion [GO:0007155]; chemical synaptic transmission [GO:0007268]; learning [GO:0007612]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; neurotransmitter secretion [GO:0007269]; postsynaptic density assembly [GO:0097107]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; trans-synaptic signaling [GO:0099537]; vocalization behavior [GO:0071625] GO:0005246; GO:0007155; GO:0007268; GO:0007269; GO:0007416; GO:0007612; GO:0030534; GO:0032991; GO:0035176; GO:0042734; GO:0046872; GO:0071625; GO:0097107; GO:0098978; GO:0098982; GO:0099072; GO:0099171; GO:0099537; GO:0099645 43057 XM_029343324.2 16 3 5 2 11 Q6P9K9 2.56e-22 Neurexin-3 (Neurexin III-alpha) (Neurexin-3-alpha) Mus musculus (Mouse) adult behavior [GO:0030534]; cell adhesion [GO:0007155]; chemical synaptic transmission [GO:0007268]; learning [GO:0007612]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; neurotransmitter secretion [GO:0007269]; postsynaptic density assembly [GO:0097107]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; trans-synaptic signaling [GO:0099537]; vocalization behavior [GO:0071625] GO:0005246; GO:0007155; GO:0007268; GO:0007269; GO:0007416; GO:0007612; GO:0030534; GO:0032991; GO:0035176; GO:0042734; GO:0046872; GO:0071625; GO:0097107; GO:0098978; GO:0098982; GO:0099072; GO:0099171; GO:0099537; GO:0099645 43058 XM_044313901.1 0 17 0 17 28 NA NA NA NA NA NA 43059 XM_029335143.2 376 173 186 341 300 NA NA NA NA NA NA 43060 XM_029345242.2 685 307 494 388 609 Q96GD3 2.37e-72 Polycomb protein SCMH1 (Sex comb on midleg homolog 1) Homo sapiens (Human) heterochromatin formation [GO:0031507]; negative regulation of DNA-templated transcription [GO:0045892] GO:0003682; GO:0005634; GO:0005654; GO:0031507; GO:0042393; GO:0045892 43061 XM_029329345.2 16 19 8 20 47 P54145 1.86e-93 Putative ammonium transporter 1 Caenorhabditis elegans ammonium homeostasis [GO:0097272]; ammonium transmembrane transport [GO:0072488] GO:0005886; GO:0008519; GO:0072488; GO:0097272 43062 XM_029352580.2 9257 4936 4335 9304 8308 Q04467 0 Isocitrate dehydrogenase [NADP], mitochondrial (IDH) (EC 1.1.1.42) (ICD-M) (IDP) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase) Bos taurus (Bovine) 2-oxoglutarate metabolic process [GO:0006103]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; NADP metabolic process [GO:0006739]; tricarboxylic acid cycle [GO:0006099] GO:0000287; GO:0004450; GO:0005739; GO:0005743; GO:0005777; GO:0005829; GO:0006097; GO:0006099; GO:0006102; GO:0006103; GO:0006739; GO:0051287 43063 XM_044323268.1 32 8 2 53 22 NA NA NA NA NA NA 43064 XM_044308712.1 140 101 94 400 215 D3YXG0 6.17e-49 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 43065 XM_044308712.1 140 101 94 400 215 D3YXG0 1.07e-48 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 43066 XM_044308712.1 140 101 94 400 215 D3YXG0 8.95e-48 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 43067 XM_044308712.1 140 101 94 400 215 D3YXG0 1.76e-46 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 43068 XM_044308712.1 140 101 94 400 215 D3YXG0 3.97e-46 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 43069 XM_044308712.1 140 101 94 400 215 D3YXG0 4.55e-46 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 43070 XM_044308712.1 140 101 94 400 215 D3YXG0 5.08e-46 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 43071 XM_044308712.1 140 101 94 400 215 D3YXG0 1.81e-45 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 43072 XM_044308712.1 140 101 94 400 215 D3YXG0 7.04e-45 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 43073 XM_044308712.1 140 101 94 400 215 D3YXG0 8.41e-45 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 43074 XM_044308712.1 140 101 94 400 215 D3YXG0 9.64e-40 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 43075 XM_044308712.1 140 101 94 400 215 D3YXG0 1.72e-37 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 43076 XM_044308712.1 140 101 94 400 215 D3YXG0 1.72e-37 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 43077 XM_044308712.1 140 101 94 400 215 D3YXG0 1.35e-31 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 43078 XM_029350180.2 349 468 479 596 1505 Q92870 9.89e-58 Amyloid beta precursor protein binding family B member 2 (Amyloid-beta (A4) precursor protein-binding family B member 2) (Protein Fe65-like 1) Homo sapiens (Human) intracellular signal transduction [GO:0035556]; maintenance of lens transparency [GO:0036438]; negative regulation of cell cycle phase transition [GO:1901988]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; smooth muscle contraction [GO:0006939]; synapse organization [GO:0050808] GO:0000122; GO:0001540; GO:0005634; GO:0005737; GO:0005769; GO:0005783; GO:0005794; GO:0006355; GO:0006939; GO:0016020; GO:0030027; GO:0030426; GO:0035556; GO:0036438; GO:0045202; GO:0045944; GO:0050808; GO:1901988 43079 XR_006391796.1 0 0 0 0 56 NA NA NA NA NA NA 43080 XM_044316869.1 0 0 0 0 42 Q98982 4.17e-27 Substance-P receptor (SPR) (NK-1 receptor) (NK-1R) (Tachykinin receptor 1) Lithobates catesbeianus (American bullfrog) (Rana catesbeiana) NA GO:0004995; GO:0005886 43081 XM_029358011.2 4706 3622 2984 4093 5182 NA NA NA NA NA NA 43082 XM_044312614.1 42 10 24 26 47 NA NA NA NA NA NA 43083 XM_044306746.1 28 39 11 130 111 NA NA NA NA NA NA 43084 XM_044316545.1 3 0 7 2 0 NA NA NA NA NA NA 43085 XM_029338507.2 5 183 8 0 0 O08658 1.3e-113 Nuclear pore complex protein Nup88 (88 kDa nucleoporin) (Nucleoporin Nup84) (Nucleoporin Nup88) Rattus norvegicus (Rat) mitotic cell cycle [GO:0000278]; mRNA export from nucleus [GO:0006406]; protein import into nucleus [GO:0006606]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056] GO:0000055; GO:0000056; GO:0000278; GO:0005635; GO:0005643; GO:0005654; GO:0006406; GO:0006606; GO:0017056 43086 XM_044325709.1 152 205 133 189 147 Q9VCP0 6.13e-38 Transcription elongation factor B polypeptide 3 (Elongin-A) (RNA polymerase II transcription factor SIII subunit A) (dEloA) Drosophila melanogaster (Fruit fly) imaginal disc-derived wing vein specification [GO:0007474]; transcription elongation by RNA polymerase II promoter [GO:0006368] GO:0005634; GO:0006368; GO:0007474; GO:0008023; GO:0070449 43087 XM_029356140.2 3 6 2 0 4 Q91770 1.63e-23 Homeobox protein not2 (Xnot-2) (Xnot2) Xenopus laevis (African clawed frog) negative regulation of DNA-templated transcription [GO:0045892]; notochord formation [GO:0014028] GO:0000981; GO:0003677; GO:0005634; GO:0014028; GO:0045892 43088 XM_029356135.2 2325 2158 2128 2785 1712 Q9HB40 3.93e-139 Retinoid-inducible serine carboxypeptidase (EC 3.4.16.-) (Serine carboxypeptidase 1) Homo sapiens (Human) blood vessel diameter maintenance [GO:0097746]; negative regulation of blood pressure [GO:0045776]; proteolysis [GO:0006508]; retinoic acid metabolic process [GO:0042573] GO:0004185; GO:0005829; GO:0006508; GO:0042573; GO:0045776; GO:0070062; GO:0097746 43089 XM_044321605.1 275 114 73 512 531 NA NA NA NA NA NA 43090 XR_006393315.1 54 4 10 20 53 NA NA NA NA NA NA 43091 XM_029325135.2 31 4 9 3 52 NA NA NA NA NA NA 43092 XM_029349492.2 1061 1025 464 765 877 Q6IRB2 1.39e-36 Transcription factor HES-1-A (Hairy and enhancer of split 1-A) (Protein hairy-1) (Xhairy-1) (Xhairy1) (Xlh1) Xenopus laevis (African clawed frog) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of muscle organ development [GO:0048635]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219] GO:0000122; GO:0005634; GO:0007219; GO:0043425; GO:0043565; GO:0045892; GO:0046982; GO:0048635 43093 XM_029339868.2 587 361 288 0 0 Q3B7U2 9.8e-24 TATA box-binding protein-associated factor RNA polymerase I subunit A (TATA box-binding protein-associated factor 1A) (TBP-associated factor 1A) (Transcription initiation factor SL1/TIF-IB subunit A) Rattus norvegicus (Rat) transcription by RNA polymerase I [GO:0006360] GO:0003677; GO:0005654; GO:0005668; GO:0006360; GO:0015630 43094 XR_006393468.1 311 87 204 438 263 NA NA NA NA NA NA 43095 XM_044322340.1 151 56 61 117 87 NA NA NA NA NA NA 43096 XR_006392427.1 0 1 21 194 29 NA NA NA NA NA NA 43097 XM_044326078.1 0 0 0 29 35 P47970 7.44e-39 Neuronal pentraxin-2 (NP2) (Acrosomal pentaxin-like protein p50) (AM50) (Neuronal pentraxin II) (Apexin) (NP-II) Cavia porcellus (Guinea pig) NA GO:0043160; GO:0046872 43098 XM_029355043.2 0 0 6 0 15 NA NA NA NA NA NA 43099 XR_006396208.1 0 20 0 0 0 NA NA NA NA NA NA 43100 XR_006393006.1 41 2 25 5 151 NA NA NA NA NA NA 43101 XM_044317439.1 10 0 0 2 0 O62852 8.27e-60 Short transient receptor potential channel 5 (Rtrp5) (TrpC5) (Capacitative calcium entry channel 2) (CCE2) Oryctolagus cuniculus (Rabbit) neuron apoptotic process [GO:0051402]; phosphatidylserine exposure on apoptotic cell surface [GO:0070782] GO:0005262; GO:0005886; GO:0034704; GO:0051402; GO:0070679; GO:0070782 43102 XM_029344597.2 0 90 42 0 0 Q9NZN8 1.52e-123 CCR4-NOT transcription complex subunit 2 (CCR4-associated factor 2) Homo sapiens (Human) negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; positive regulation of cytoplasmic mRNA processing body assembly [GO:0010606]; regulation of stem cell population maintenance [GO:2000036]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; RNA-mediated gene silencing [GO:0031047]; trophectodermal cell differentiation [GO:0001829] GO:0000122; GO:0000289; GO:0000932; GO:0001222; GO:0001829; GO:0003712; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0006357; GO:0010606; GO:0016020; GO:0030014; GO:0030015; GO:0031047; GO:0033147; GO:0090503; GO:2000036 43103 XM_029323859.2 199 171 149 601 186 NA NA NA NA NA NA 43104 XR_006392165.1 13 0 17 121 42 NA NA NA NA NA NA 43105 XM_044327822.1 0 13 1 0 0 NA NA NA NA NA NA 43106 XM_044308157.1 116 0 174 256 122 P00521 3.5e-27 Tyrosine-protein kinase transforming protein Abl (EC 2.7.10.2) (V-abl) Abelson murine leukemia virus NA GO:0004715; GO:0005524 43107 XM_044322541.1 347 168 114 748 219 Q8BHP7 4.49e-52 Olfactomedin-like protein 2A (Photomedin-1) Mus musculus (Mouse) extracellular matrix organization [GO:0030198]; signal transduction [GO:0007165] GO:0005615; GO:0007165; GO:0030198; GO:0031012; GO:0042802; GO:0050840 43108 XM_029346529.2 104 383 802 875 1278 Q9I8C7 3.45e-93 Neuronal acetylcholine receptor subunit alpha-10 (Alpha 10 nAChR) (Nicotinic acetylcholine receptor subunit alpha-10) (NACHR alpha-10) Gallus gallus (Chicken) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; response to auditory stimulus [GO:0010996]; signal transduction [GO:0007165] GO:0004888; GO:0005231; GO:0005262; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0010996; GO:0022848; GO:0030594; GO:0034220; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051899; GO:1904315 43109 XM_044319029.1 62 1 51 9 9 Q9UHC6 8.17e-37 Contactin-associated protein-like 2 (Cell recognition molecule Caspr2) Homo sapiens (Human) adult behavior [GO:0030534]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell population proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; clustering of voltage-gated potassium channels [GO:0045163]; learning [GO:0007612]; limbic system development [GO:0021761]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuron recognition [GO:0008038]; positive regulation of gap junction assembly [GO:1903598]; protein localization to juxtaparanode region of axon [GO:0071205]; social behavior [GO:0035176]; striatum development [GO:0021756]; superior temporal gyrus development [GO:0071109]; thalamus development [GO:0021794]; transmission of nerve impulse [GO:0019226]; vocal learning [GO:0042297]; vocalization behavior [GO:0071625] GO:0005769; GO:0005794; GO:0007155; GO:0007420; GO:0007612; GO:0008038; GO:0008076; GO:0008283; GO:0009986; GO:0016020; GO:0019226; GO:0019899; GO:0021756; GO:0021761; GO:0021794; GO:0021987; GO:0030424; GO:0030425; GO:0030534; GO:0030673; GO:0031175; GO:0033010; GO:0035176; GO:0042297; GO:0043025; GO:0043204; GO:0044224; GO:0045163; GO:0048812; GO:0071109; GO:0071205; GO:0071625; GO:1903598 43110 XM_029347297.2 0 0 0 0 11 NA NA NA NA NA NA 43111 XM_029336745.2 1929 1724 2450 2852 1402 P62168 9.76e-104 Neuronal calcium sensor 1 (NCS-1) (Frequenin homolog) (Frequenin-like protein) (Frequenin-like ubiquitous protein) Rattus norvegicus (Rat) phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of exocytosis [GO:0045921]; regulation of neuron projection development [GO:0010975]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509]; regulation of synaptic vesicle exocytosis [GO:2000300] GO:0000287; GO:0005245; GO:0005509; GO:0005737; GO:0005794; GO:0005829; GO:0005886; GO:0008048; GO:0008427; GO:0010975; GO:0014069; GO:0019901; GO:0030424; GO:0030425; GO:0031410; GO:0044305; GO:0045921; GO:0048015; GO:0048471; GO:0098794; GO:0098978; GO:0099509; GO:0099523; GO:0099524; GO:2000300 43112 XR_006393346.1 152 2 23 20 851 NA NA NA NA NA NA 43113 XM_029343100.2 914 534 400 796 1001 NA NA NA NA NA NA 43114 XM_029339071.2 132 5 39 226 136 NA NA NA NA NA NA 43115 XM_029330540.2 864 461 176 545 378 Q96AY4 4.96e-81 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 43116 XM_029330540.2 864 461 176 545 378 Q96AY4 7.27e-80 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 43117 XM_029330540.2 864 461 176 545 378 Q96AY4 3.69e-77 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 43118 XM_029330540.2 864 461 176 545 378 Q96AY4 1.54e-76 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 43119 XM_029330540.2 864 461 176 545 378 Q96AY4 5.34e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 43120 XM_044324792.1 256 420 108 547 92 P35546 1.1e-78 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; anatomical structure morphogenesis [GO:0009653]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006919; GO:0007156; GO:0007158; GO:0007169; GO:0007399; GO:0009410; GO:0009653; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030182; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0098797; GO:2001241 43121 XM_044316796.1 9 0 0 4 9 NA NA NA NA NA NA 43122 XM_044308856.1 0 0 0 0 12 P54763 2.81e-50 Ephrin type-B receptor 2 (EC 2.7.10.1) (Neural kinase) (Nuk receptor tyrosine kinase) (Tyrosine-protein kinase receptor EPH-3) (Tyrosine-protein kinase receptor SEK-3) [Cleaved into: EphB2/CTF1; EphB2/CTF2] Mus musculus (Mouse) angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; axonogenesis [GO:0007409]; B cell activation [GO:0042113]; camera-type eye morphogenesis [GO:0048593]; cell morphogenesis [GO:0000902]; cellular response to amyloid-beta [GO:1904646]; cellular response to lipopolysaccharide [GO:0071222]; central nervous system projection neuron axonogenesis [GO:0021952]; commissural neuron axon guidance [GO:0071679]; corpus callosum development [GO:0022038]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; ephrin receptor signaling pathway [GO:0048013]; hindbrain tangential cell migration [GO:0021934]; inner ear morphogenesis [GO:0042472]; learning [GO:0007612]; learning or memory [GO:0007611]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of NMDA glutamate receptor activity [GO:1904782]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; neuron projection retraction [GO:0106028]; optic nerve morphogenesis [GO:0021631]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphorylation [GO:0016310]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell migration [GO:0030335]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of gene expression [GO:0010628]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of kinase activity [GO:0033674]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of tumor necrosis factor production [GO:0032760]; postsynaptic membrane assembly [GO:0097104]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of behavioral fear response [GO:2000822]; regulation of blood coagulation [GO:0030193]; regulation of body fluid levels [GO:0050878]; regulation of filopodium assembly [GO:0051489]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of receptor signaling pathway via JAK-STAT [GO:0046425]; regulation of synapse assembly [GO:0051963]; regulation of T-helper 17 type immune response [GO:2000316]; retinal ganglion cell axon guidance [GO:0031290]; roof of mouth development [GO:0060021]; tight junction assembly [GO:0120192]; trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission [GO:0099557]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; urogenital system development [GO:0001655]; vesicle-mediated intercellular transport [GO:0110077] GO:0000902; GO:0001525; GO:0001540; GO:0001655; GO:0001933; GO:0002639; GO:0004713; GO:0004714; GO:0005003; GO:0005005; GO:0005102; GO:0005524; GO:0005654; GO:0005794; GO:0005886; GO:0006468; GO:0006469; GO:0007162; GO:0007169; GO:0007409; GO:0007411; GO:0007413; GO:0007611; GO:0007612; GO:0008046; GO:0009887; GO:0009986; GO:0010628; GO:0016310; GO:0018108; GO:0021631; GO:0021934; GO:0021952; GO:0022038; GO:0030193; GO:0030335; GO:0030424; GO:0030425; GO:0030890; GO:0031290; GO:0031915; GO:0032760; GO:0033674; GO:0038023; GO:0042113; GO:0042472; GO:0042734; GO:0042802; GO:0043005; GO:0043025; GO:0043197; GO:0043235; GO:0044877; GO:0045202; GO:0045211; GO:0046425; GO:0046580; GO:0048013; GO:0048168; GO:0048170; GO:0048593; GO:0050770; GO:0050771; GO:0050878; GO:0051489; GO:0051963; GO:0051965; GO:0060021; GO:0060996; GO:0060997; GO:0061003; GO:0070373; GO:0071222; GO:0071679; GO:0097104; GO:0098686; GO:0098794; GO:0098978; GO:0099557; GO:0106028; GO:0110077; GO:0120192; GO:1900016; GO:1900273; GO:1903078; GO:1904646; GO:1904782; GO:1904783; GO:2000010; GO:2000316; GO:2000822 43123 XM_044308856.1 0 0 0 0 12 P54763 2.81e-50 Ephrin type-B receptor 2 (EC 2.7.10.1) (Neural kinase) (Nuk receptor tyrosine kinase) (Tyrosine-protein kinase receptor EPH-3) (Tyrosine-protein kinase receptor SEK-3) [Cleaved into: EphB2/CTF1; EphB2/CTF2] Mus musculus (Mouse) angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; axonogenesis [GO:0007409]; B cell activation [GO:0042113]; camera-type eye morphogenesis [GO:0048593]; cell morphogenesis [GO:0000902]; cellular response to amyloid-beta [GO:1904646]; cellular response to lipopolysaccharide [GO:0071222]; central nervous system projection neuron axonogenesis [GO:0021952]; commissural neuron axon guidance [GO:0071679]; corpus callosum development [GO:0022038]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; ephrin receptor signaling pathway [GO:0048013]; hindbrain tangential cell migration [GO:0021934]; inner ear morphogenesis [GO:0042472]; learning [GO:0007612]; learning or memory [GO:0007611]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of NMDA glutamate receptor activity [GO:1904782]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; neuron projection retraction [GO:0106028]; optic nerve morphogenesis [GO:0021631]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphorylation [GO:0016310]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell migration [GO:0030335]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of gene expression [GO:0010628]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of kinase activity [GO:0033674]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of tumor necrosis factor production [GO:0032760]; postsynaptic membrane assembly [GO:0097104]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of behavioral fear response [GO:2000822]; regulation of blood coagulation [GO:0030193]; regulation of body fluid levels [GO:0050878]; regulation of filopodium assembly [GO:0051489]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of receptor signaling pathway via JAK-STAT [GO:0046425]; regulation of synapse assembly [GO:0051963]; regulation of T-helper 17 type immune response [GO:2000316]; retinal ganglion cell axon guidance [GO:0031290]; roof of mouth development [GO:0060021]; tight junction assembly [GO:0120192]; trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission [GO:0099557]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; urogenital system development [GO:0001655]; vesicle-mediated intercellular transport [GO:0110077] GO:0000902; GO:0001525; GO:0001540; GO:0001655; GO:0001933; GO:0002639; GO:0004713; GO:0004714; GO:0005003; GO:0005005; GO:0005102; GO:0005524; GO:0005654; GO:0005794; GO:0005886; GO:0006468; GO:0006469; GO:0007162; GO:0007169; GO:0007409; GO:0007411; GO:0007413; GO:0007611; GO:0007612; GO:0008046; GO:0009887; GO:0009986; GO:0010628; GO:0016310; GO:0018108; GO:0021631; GO:0021934; GO:0021952; GO:0022038; GO:0030193; GO:0030335; GO:0030424; GO:0030425; GO:0030890; GO:0031290; GO:0031915; GO:0032760; GO:0033674; GO:0038023; GO:0042113; GO:0042472; GO:0042734; GO:0042802; GO:0043005; GO:0043025; GO:0043197; GO:0043235; GO:0044877; GO:0045202; GO:0045211; GO:0046425; GO:0046580; GO:0048013; GO:0048168; GO:0048170; GO:0048593; GO:0050770; GO:0050771; GO:0050878; GO:0051489; GO:0051963; GO:0051965; GO:0060021; GO:0060996; GO:0060997; GO:0061003; GO:0070373; GO:0071222; GO:0071679; GO:0097104; GO:0098686; GO:0098794; GO:0098978; GO:0099557; GO:0106028; GO:0110077; GO:0120192; GO:1900016; GO:1900273; GO:1903078; GO:1904646; GO:1904782; GO:1904783; GO:2000010; GO:2000316; GO:2000822 43124 XM_029344564.1 805 833 448 549 634 NA NA NA NA NA NA 43125 XM_029341849.2 919 790 495 1983 1777 B0VYY5 7.66e-45 Cytochrome c oxidase subunit 5A, mitochondrial (Cytochrome c oxidase polypeptide Va) Notamacropus parma (Parma wallaby) (Macropus parma) mitochondrial electron transport, cytochrome c to oxygen [GO:0006123] GO:0005751; GO:0006123; GO:0046872 43126 XM_029353008.2 1169 1160 806 555 350 NA NA NA NA NA NA 43127 XM_044321970.1 0 10 20 47 0 O75486 1.41e-50 Transcription initiation protein SPT3 homolog (SPT3-like protein) Homo sapiens (Human) histone acetylation [GO:0016573]; histone H3 acetylation [GO:0043966]; monoubiquitinated histone deubiquitination [GO:0035521]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA repair [GO:0006282]; regulation of DNA-templated transcription [GO:0006355]; regulation of RNA splicing [GO:0043484]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366] GO:0000124; GO:0003713; GO:0005634; GO:0005654; GO:0006282; GO:0006355; GO:0006357; GO:0006366; GO:0016573; GO:0033276; GO:0035521; GO:0035522; GO:0043484; GO:0043966; GO:0045893; GO:0046982 43128 XM_044308350.1 5716 1949 638 2591 2355 Q5R4N8 2.35e-170 Alpha-2-macroglobulin (Alpha-2-M) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) negative regulation of peptidase activity [GO:0010466] GO:0004867; GO:0005615; GO:0010466 43129 XM_044308350.1 5716 1949 638 2591 2355 Q5R4N8 2.35e-170 Alpha-2-macroglobulin (Alpha-2-M) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) negative regulation of peptidase activity [GO:0010466] GO:0004867; GO:0005615; GO:0010466 43130 XM_029334240.2 131 247 231 268 196 P25931 2.23e-33 RYamide receptor (Neuropeptide Y-like receptor) (NPY-R) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218] GO:0001653; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0016020 43131 XM_044328999.1 7 0 0 0 0 NA NA NA NA NA NA 43132 XM_044321130.1 7 13 4 11 4 M9NDE3 1.61e-23 Protein bark beetle (Protein anakonda) Drosophila melanogaster (Fruit fly) cell-cell junction maintenance [GO:0045217]; liquid clearance, open tracheal system [GO:0035002]; regulation of tube length, open tracheal system [GO:0035159]; response to endoplasmic reticulum stress [GO:0034976]; tricellular tight junction assembly [GO:1904274] GO:0005044; GO:0005912; GO:0005918; GO:0005923; GO:0016328; GO:0030246; GO:0034976; GO:0035002; GO:0035159; GO:0045217; GO:0061689; GO:1904274 43133 XM_044321767.1 685 319 618 1592 782 Q5R4J5 4.16e-21 Synaptotagmin-1 (Synaptotagmin I) (SytI) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cell differentiation [GO:0030154]; positive regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903235] GO:0030154; GO:0030672; GO:0042584; GO:0046872; GO:1903235 43134 XM_029338448.2 391 302 358 351 602 Q9Y4C8 0 Probable RNA-binding protein 19 (RNA-binding motif protein 19) Homo sapiens (Human) mRNA splicing, via spliceosome [GO:0000398]; positive regulation of embryonic development [GO:0040019] GO:0000398; GO:0003723; GO:0005654; GO:0005694; GO:0005730; GO:0005737; GO:0016020; GO:0016607; GO:0040019 43135 XM_029351365.2 109 32 63 83 162 Q969F8 1.96e-24 KiSS-1 receptor (KiSS-1R) (G-protein coupled receptor 54) (G-protein coupled receptor OT7T175) (hOT7T175) (Hypogonadotropin-1) (Kisspeptins receptor) (Metastin receptor) Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218] GO:0005886; GO:0005929; GO:0007186; GO:0007218; GO:0008188; GO:0008528; GO:0009986; GO:0016020; GO:0043231 43136 XM_029341211.2 1444 611 775 820 1051 A8WGF4 0 Intraflagellar transport protein 122 homolog Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cilium assembly [GO:0060271]; intraciliary retrograde transport [GO:0035721]; intraciliary transport [GO:0042073]; negative regulation of smoothened signaling pathway [GO:0045879]; protein localization to cilium [GO:0061512] GO:0005737; GO:0005929; GO:0030991; GO:0035721; GO:0036064; GO:0042073; GO:0045879; GO:0060271; GO:0061512 43137 XM_029339832.2 551 480 229 381 164 NA NA NA NA NA NA 43138 XM_044307250.1 436 380 345 488 214 Q92820 5.97e-87 Gamma-glutamyl hydrolase (EC 3.4.19.9) (Conjugase) (GH) (Gamma-Glu-X carboxypeptidase) Homo sapiens (Human) tetrahydrofolylpolyglutamate metabolic process [GO:0046900] GO:0005576; GO:0005615; GO:0005634; GO:0005773; GO:0008238; GO:0008242; GO:0034722; GO:0035578; GO:0035580; GO:0042470; GO:0046900; GO:0070062; GO:1904724 43139 XM_029344021.2 1992 2310 1247 1572 1375 NA NA NA NA NA NA 43140 XM_029331903.2 1632 1451 1135 1055 1199 Q6PZ02 1.08e-120 Cysteine protease ATG4B (EC 3.4.22.-) (Autophagy-related cysteine endopeptidase 2B) (Autophagin-2B) (cAut2B) (Autophagy-related protein 4 homolog B) Gallus gallus (Chicken) autophagy [GO:0006914]; lysosomal microautophagy [GO:0016237]; mitophagy [GO:0000423]; otolith mineralization completed early in development [GO:0031173]; protein transport [GO:0015031]; proteolysis [GO:0006508] GO:0000423; GO:0005739; GO:0005776; GO:0005783; GO:0005829; GO:0006508; GO:0006914; GO:0015031; GO:0016237; GO:0019786; GO:0031173; GO:0031410 43141 XR_006393078.1 41 2 25 5 151 NA NA NA NA NA NA 43142 XM_029346593.2 0 57 0 0 69 Q9CXE6 6.32e-69 DNA repair protein XRCC3 (X-ray repair cross-complementing protein 3) Mus musculus (Mouse) DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via synthesis-dependent strand annealing [GO:0045003]; interstrand cross-link repair [GO:0036297]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; regulation of centrosome duplication [GO:0010824]; resolution of mitotic recombination intermediates [GO:0071140]; response to organic substance [GO:0010033]; t-circle formation [GO:0090656]; telomere maintenance via recombination [GO:0000722]; telomere maintenance via telomere trimming [GO:0090737] GO:0000400; GO:0000722; GO:0000724; GO:0005524; GO:0005634; GO:0005654; GO:0005657; GO:0005737; GO:0005739; GO:0005759; GO:0005829; GO:0006281; GO:0008821; GO:0010033; GO:0010824; GO:0033065; GO:0036297; GO:0045003; GO:0048471; GO:0071140; GO:0090267; GO:0090656; GO:0090737; GO:0140664 43143 XR_006396320.1 775 1575 140 951 232 NA NA NA NA NA NA 43144 XM_044327964.1 14 0 29 7 33 Q17RP2 9.74e-76 Tigger transposable element-derived protein 6 Homo sapiens (Human) NA GO:0003677; GO:0005634 43145 XM_044324626.1 17 14 14 1 30 NA NA NA NA NA NA 43146 XM_029338589.2 2252 1443 1375 2454 2494 Q13976 0 cGMP-dependent protein kinase 1 (cGK 1) (cGK1) (EC 2.7.11.12) (cGMP-dependent protein kinase I) (cGKI) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cGMP-mediated signaling [GO:0019934]; collateral sprouting [GO:0048668]; dendrite development [GO:0016358]; forebrain development [GO:0030900]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; negative regulation of vascular associated smooth muscle cell proliferation [GO:1904706]; neuron migration [GO:0001764]; protein phosphorylation [GO:0006468]; regulation of GTPase activity [GO:0043087]; relaxation of vascular associated smooth muscle [GO:0060087]; signal transduction [GO:0007165] GO:0001764; GO:0004672; GO:0004692; GO:0005246; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005886; GO:0006468; GO:0007165; GO:0016358; GO:0019934; GO:0030036; GO:0030553; GO:0030900; GO:0042802; GO:0043087; GO:0048668; GO:0060087; GO:0090331; GO:0106310; GO:1904706; GO:1904753 43147 XR_006397050.1 872 406 343 285 501 NA NA NA NA NA NA 43148 XM_044307040.1 3 16 0 0 7 P0DP43 1.09e-30 Cation channel sperm-associated auxiliary subunit epsilon (CatSper-epsilon) (CatSperepsilon) (C1orf101-like protein) Mus musculus (Mouse) flagellated sperm motility [GO:0030317]; sperm capacitation [GO:0048240] GO:0030317; GO:0036128; GO:0048240; GO:0097228 43149 XR_006393773.1 4 0 0 9 0 NA NA NA NA NA NA 43150 XM_044328767.1 405 462 572 495 1221 NA NA NA NA NA NA 43151 XM_044313610.1 2 0 8 0 4 NA NA NA NA NA NA 43152 XM_029333040.2 2525 2672 1404 1747 1575 Q9QYU1 2.35e-38 Peroxisomal biogenesis factor 19 (Peroxin-19) (Peroxisomal farnesylated protein) Rattus norvegicus (Rat) chaperone-mediated protein folding [GO:0061077]; establishment of protein localization to peroxisome [GO:0072663]; negative regulation of lipid binding [GO:1900131]; peroxisome fission [GO:0016559]; peroxisome organization [GO:0007031]; protein import into peroxisome membrane [GO:0045046]; protein stabilization [GO:0050821]; protein targeting to peroxisome [GO:0006625] GO:0005737; GO:0005777; GO:0005778; GO:0005829; GO:0006625; GO:0007031; GO:0016559; GO:0031526; GO:0032991; GO:0033328; GO:0036105; GO:0045046; GO:0047485; GO:0050821; GO:0051117; GO:0061077; GO:0072663; GO:0140597; GO:1900131 43153 XM_044326994.1 1264 858 706 1195 960 NA NA NA NA NA NA 43154 XR_006395784.1 22 12 32 2 11 O54956 4.95e-156 DNA polymerase epsilon subunit 2 (DNA polymerase II subunit 2) (DNA polymerase epsilon subunit B) Mus musculus (Mouse) DNA-templated DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276] GO:0003677; GO:0005654; GO:0006261; GO:0008622; GO:0016604; GO:0042276; GO:0043231 43155 XR_006395784.1 22 12 32 2 11 O54956 6.86e-36 DNA polymerase epsilon subunit 2 (DNA polymerase II subunit 2) (DNA polymerase epsilon subunit B) Mus musculus (Mouse) DNA-templated DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276] GO:0003677; GO:0005654; GO:0006261; GO:0008622; GO:0016604; GO:0042276; GO:0043231 43156 XR_006394088.1 139 156 73 91 65 NA NA NA NA NA NA 43157 XM_044315696.1 34 1 7 49 17 Q94K49 2.73e-24 Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1 (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) epigenetic regulation of gene expression [GO:0040029] GO:0003682; GO:0004518; GO:0005634; GO:0035098; GO:0035102; GO:0040029; GO:0046872 43158 XR_006392206.1 54 19 0 24 107 NA NA NA NA NA NA 43159 XR_006395273.1 20 6 19 9 28 NA NA NA NA NA NA 43160 XM_029353103.2 1 0 3 0 8 NA NA NA NA NA NA 43161 XM_029342730.2 0 0 0 0 11 NA NA NA NA NA NA 43162 XR_006397087.1 296 42 434 57 1191 Q8BR76 2.02e-34 Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67) Mus musculus (Mouse) branching morphogenesis of an epithelial tube [GO:0048754]; cilium assembly [GO:0060271]; determination of left/right symmetry [GO:0007368]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; head development [GO:0060322]; heart development [GO:0007507]; kidney development [GO:0001822]; negative regulation of centrosome duplication [GO:0010826]; non-canonical Wnt signaling pathway [GO:0035567]; photoreceptor cell outer segment organization [GO:0035845]; positive regulation of ERAD pathway [GO:1904294]; positive regulation of non-motile cilium assembly [GO:1902857]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0001822; GO:0005789; GO:0005813; GO:0005886; GO:0005929; GO:0005930; GO:0007368; GO:0007507; GO:0010826; GO:0030433; GO:0030659; GO:0031005; GO:0035567; GO:0035845; GO:0035869; GO:0036038; GO:0048754; GO:0051082; GO:0051787; GO:0060170; GO:0060271; GO:0060322; GO:0060441; GO:1902857; GO:1904294 43163 XM_029349455.2 1442 1472 808 1063 615 A7RWC9 4.27e-111 Inosine triphosphate pyrophosphatase (ITPase) (Inosine triphosphatase) (EC 3.6.1.9) (Non-canonical purine NTP pyrophosphatase) (Non-standard purine NTP pyrophosphatase) (Nucleoside-triphosphate diphosphatase) (Nucleoside-triphosphate pyrophosphatase) (NTPase) Nematostella vectensis (Starlet sea anemone) deoxyribonucleoside triphosphate catabolic process [GO:0009204]; nucleoside triphosphate catabolic process [GO:0009143]; nucleotide metabolic process [GO:0009117] GO:0000166; GO:0005737; GO:0009117; GO:0009143; GO:0009204; GO:0035870; GO:0036220; GO:0036222; GO:0046872; GO:0047429 43164 XM_029344121.2 30 1 0 5 15 NA NA NA NA NA NA 43165 XM_044321161.1 18 52 22 67 41 NA NA NA NA NA NA 43166 XR_006395729.1 47 11 38 3 89 NA NA NA NA NA NA 43167 XM_044327771.1 116 67 169 173 279 Q8R4G6 9.17e-155 Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (EC 2.4.1.155) (Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase) (GlcNAc-T V) (GNT-V) (Mannoside acetylglucosaminyltransferase 5) (N-acetylglucosaminyl-transferase V) [Cleaved into: Secreted alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (Secreted beta-1,6-N-acetylglucosaminyltransferase V) (Secreted GNT-V)] Mus musculus (Mouse) negative regulation of protein tyrosine phosphatase activity [GO:1903614]; positive regulation of cell migration [GO:0030335]; positive regulation of receptor signaling pathway via STAT [GO:1904894]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279] GO:0000139; GO:0004864; GO:0005576; GO:0005794; GO:0006487; GO:0008375; GO:0016020; GO:0016757; GO:0018279; GO:0030144; GO:0030145; GO:0030335; GO:0043204; GO:1903614; GO:1904894 43168 XM_044329011.1 27 34 13 39 77 NA NA NA NA NA NA 43169 XM_044327080.1 11 34 7 1 15 NA NA NA NA NA NA 43170 XM_029333539.2 4459 7386 3676 2988 2538 P45878 4.01e-65 Peptidyl-prolyl cis-trans isomerase FKBP2 (PPIase FKBP2) (EC 5.2.1.8) (13 kDa FK506-binding protein) (13 kDa FKBP) (FKBP-13) (FK506-binding protein 2) (FKBP-2) (Immunophilin FKBP13) (Rotamase) Mus musculus (Mouse) chaperone-mediated protein folding [GO:0061077]; protein peptidyl-prolyl isomerization [GO:0000413] GO:0000413; GO:0003755; GO:0005783; GO:0005789; GO:0061077 43171 XM_029348477.2 300 136 47 228 72 Q8K596 6.13e-73 Sodium/calcium exchanger 2 (Na(+)/Ca(2+)-exchange protein 2) (Solute carrier family 8 member 2) Mus musculus (Mouse) calcium ion export across plasma membrane [GO:1990034]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport into cytosol [GO:0060402]; cell communication [GO:0007154]; cellular calcium ion homeostasis [GO:0006874]; cognition [GO:0050890]; learning [GO:0007612]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; metal ion transport [GO:0030001]; modulation of excitatory postsynaptic potential [GO:0098815]; neuron cellular homeostasis [GO:0070050]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; regulation of action potential firing pattern [GO:0099608]; regulation of calcineurin-mediated signaling [GO:0106056]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; response to ischemia [GO:0002931]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814]; synapse organization [GO:0050808] GO:0002931; GO:0005432; GO:0005516; GO:0005739; GO:0005874; GO:0005886; GO:0006814; GO:0006874; GO:0007154; GO:0007611; GO:0007612; GO:0007613; GO:0010468; GO:0014069; GO:0015081; GO:0015085; GO:0016020; GO:0016323; GO:0030001; GO:0030424; GO:0030425; GO:0035725; GO:0042383; GO:0042995; GO:0043025; GO:0043197; GO:0043679; GO:0045202; GO:0045211; GO:0046872; GO:0048172; GO:0050808; GO:0050890; GO:0051480; GO:0060291; GO:0060402; GO:0070050; GO:0070588; GO:0071902; GO:0098703; GO:0098793; GO:0098794; GO:0098815; GO:0099608; GO:0106056; GO:1905060; GO:1990034 43172 XM_029348477.2 300 136 47 228 72 Q8K596 1.47e-43 Sodium/calcium exchanger 2 (Na(+)/Ca(2+)-exchange protein 2) (Solute carrier family 8 member 2) Mus musculus (Mouse) calcium ion export across plasma membrane [GO:1990034]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport into cytosol [GO:0060402]; cell communication [GO:0007154]; cellular calcium ion homeostasis [GO:0006874]; cognition [GO:0050890]; learning [GO:0007612]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; metal ion transport [GO:0030001]; modulation of excitatory postsynaptic potential [GO:0098815]; neuron cellular homeostasis [GO:0070050]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; regulation of action potential firing pattern [GO:0099608]; regulation of calcineurin-mediated signaling [GO:0106056]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; response to ischemia [GO:0002931]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814]; synapse organization [GO:0050808] GO:0002931; GO:0005432; GO:0005516; GO:0005739; GO:0005874; GO:0005886; GO:0006814; GO:0006874; GO:0007154; GO:0007611; GO:0007612; GO:0007613; GO:0010468; GO:0014069; GO:0015081; GO:0015085; GO:0016020; GO:0016323; GO:0030001; GO:0030424; GO:0030425; GO:0035725; GO:0042383; GO:0042995; GO:0043025; GO:0043197; GO:0043679; GO:0045202; GO:0045211; GO:0046872; GO:0048172; GO:0050808; GO:0050890; GO:0051480; GO:0060291; GO:0060402; GO:0070050; GO:0070588; GO:0071902; GO:0098703; GO:0098793; GO:0098794; GO:0098815; GO:0099608; GO:0106056; GO:1905060; GO:1990034 43173 XR_006393512.1 62 52 0 26 62 NA NA NA NA NA NA 43174 XM_029354893.2 3 2 7 5 59 NA NA NA NA NA NA 43175 XM_044307430.1 956 319 783 590 683 Q9NR09 3.36e-176 Baculoviral IAP repeat-containing protein 6 (EC 2.3.2.27) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (RING-type E3 ubiquitin transferase BIRC6) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON) Homo sapiens (Human) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell population proliferation [GO:0008283]; labyrinthine layer development [GO:0060711]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of peptidase activity [GO:0010466]; positive regulation of cell population proliferation [GO:0008284]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell population proliferation [GO:0042127]; regulation of cytokinesis [GO:0032465]; regulation of endopeptidase activity [GO:0052548]; spongiotrophoblast layer development [GO:0060712] GO:0000922; GO:0004842; GO:0004869; GO:0005634; GO:0005768; GO:0005802; GO:0005815; GO:0005829; GO:0006468; GO:0006915; GO:0007049; GO:0008283; GO:0008284; GO:0010466; GO:0016020; GO:0016567; GO:0030496; GO:0032465; GO:0042127; GO:0043066; GO:0051301; GO:0052548; GO:0060711; GO:0060712; GO:0061631; GO:0090543; GO:2001237 43176 XM_044307430.1 956 319 783 590 683 Q9NR09 3.91e-91 Baculoviral IAP repeat-containing protein 6 (EC 2.3.2.27) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (RING-type E3 ubiquitin transferase BIRC6) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON) Homo sapiens (Human) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell population proliferation [GO:0008283]; labyrinthine layer development [GO:0060711]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of peptidase activity [GO:0010466]; positive regulation of cell population proliferation [GO:0008284]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell population proliferation [GO:0042127]; regulation of cytokinesis [GO:0032465]; regulation of endopeptidase activity [GO:0052548]; spongiotrophoblast layer development [GO:0060712] GO:0000922; GO:0004842; GO:0004869; GO:0005634; GO:0005768; GO:0005802; GO:0005815; GO:0005829; GO:0006468; GO:0006915; GO:0007049; GO:0008283; GO:0008284; GO:0010466; GO:0016020; GO:0016567; GO:0030496; GO:0032465; GO:0042127; GO:0043066; GO:0051301; GO:0052548; GO:0060711; GO:0060712; GO:0061631; GO:0090543; GO:2001237 43177 XM_044307430.1 956 319 783 590 683 Q9NR09 9.63e-72 Baculoviral IAP repeat-containing protein 6 (EC 2.3.2.27) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (RING-type E3 ubiquitin transferase BIRC6) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON) Homo sapiens (Human) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell population proliferation [GO:0008283]; labyrinthine layer development [GO:0060711]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of peptidase activity [GO:0010466]; positive regulation of cell population proliferation [GO:0008284]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell population proliferation [GO:0042127]; regulation of cytokinesis [GO:0032465]; regulation of endopeptidase activity [GO:0052548]; spongiotrophoblast layer development [GO:0060712] GO:0000922; GO:0004842; GO:0004869; GO:0005634; GO:0005768; GO:0005802; GO:0005815; GO:0005829; GO:0006468; GO:0006915; GO:0007049; GO:0008283; GO:0008284; GO:0010466; GO:0016020; GO:0016567; GO:0030496; GO:0032465; GO:0042127; GO:0043066; GO:0051301; GO:0052548; GO:0060711; GO:0060712; GO:0061631; GO:0090543; GO:2001237 43178 XM_044307430.1 956 319 783 590 683 Q9NR09 1.12e-56 Baculoviral IAP repeat-containing protein 6 (EC 2.3.2.27) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (RING-type E3 ubiquitin transferase BIRC6) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON) Homo sapiens (Human) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell population proliferation [GO:0008283]; labyrinthine layer development [GO:0060711]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of peptidase activity [GO:0010466]; positive regulation of cell population proliferation [GO:0008284]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell population proliferation [GO:0042127]; regulation of cytokinesis [GO:0032465]; regulation of endopeptidase activity [GO:0052548]; spongiotrophoblast layer development [GO:0060712] GO:0000922; GO:0004842; GO:0004869; GO:0005634; GO:0005768; GO:0005802; GO:0005815; GO:0005829; GO:0006468; GO:0006915; GO:0007049; GO:0008283; GO:0008284; GO:0010466; GO:0016020; GO:0016567; GO:0030496; GO:0032465; GO:0042127; GO:0043066; GO:0051301; GO:0052548; GO:0060711; GO:0060712; GO:0061631; GO:0090543; GO:2001237 43179 XM_044307430.1 956 319 783 590 683 Q9NR09 2.08e-33 Baculoviral IAP repeat-containing protein 6 (EC 2.3.2.27) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (RING-type E3 ubiquitin transferase BIRC6) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON) Homo sapiens (Human) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell population proliferation [GO:0008283]; labyrinthine layer development [GO:0060711]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of peptidase activity [GO:0010466]; positive regulation of cell population proliferation [GO:0008284]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell population proliferation [GO:0042127]; regulation of cytokinesis [GO:0032465]; regulation of endopeptidase activity [GO:0052548]; spongiotrophoblast layer development [GO:0060712] GO:0000922; GO:0004842; GO:0004869; GO:0005634; GO:0005768; GO:0005802; GO:0005815; GO:0005829; GO:0006468; GO:0006915; GO:0007049; GO:0008283; GO:0008284; GO:0010466; GO:0016020; GO:0016567; GO:0030496; GO:0032465; GO:0042127; GO:0043066; GO:0051301; GO:0052548; GO:0060711; GO:0060712; GO:0061631; GO:0090543; GO:2001237 43180 XM_044307430.1 956 319 783 590 683 Q9NR09 6.07e-32 Baculoviral IAP repeat-containing protein 6 (EC 2.3.2.27) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (RING-type E3 ubiquitin transferase BIRC6) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON) Homo sapiens (Human) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell population proliferation [GO:0008283]; labyrinthine layer development [GO:0060711]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of peptidase activity [GO:0010466]; positive regulation of cell population proliferation [GO:0008284]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell population proliferation [GO:0042127]; regulation of cytokinesis [GO:0032465]; regulation of endopeptidase activity [GO:0052548]; spongiotrophoblast layer development [GO:0060712] GO:0000922; GO:0004842; GO:0004869; GO:0005634; GO:0005768; GO:0005802; GO:0005815; GO:0005829; GO:0006468; GO:0006915; GO:0007049; GO:0008283; GO:0008284; GO:0010466; GO:0016020; GO:0016567; GO:0030496; GO:0032465; GO:0042127; GO:0043066; GO:0051301; GO:0052548; GO:0060711; GO:0060712; GO:0061631; GO:0090543; GO:2001237 43181 XM_029333408.2 1345 980 576 989 721 NA NA NA NA NA NA 43182 XR_006392325.1 89 9 30 8 86 NA NA NA NA NA NA 43183 XM_044325923.1 181 208 75 85 319 P10079 3.71e-61 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 43184 XM_044325923.1 181 208 75 85 319 P10079 2.13e-60 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 43185 XM_044325923.1 181 208 75 85 319 P10079 2.99e-58 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 43186 XM_044325923.1 181 208 75 85 319 P10079 4.18e-43 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 43187 XM_044325923.1 181 208 75 85 319 P10079 1.36e-38 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 43188 XM_044325923.1 181 208 75 85 319 P10079 3.05e-36 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 43189 XM_044327987.1 44 12 9 13 10 NA NA NA NA NA NA 43190 XM_044308536.1 81 159 155 372 251 NA NA NA NA NA NA 43191 XM_029337142.2 807 637 554 597 358 Q5E985 2.23e-90 Hyaluronidase-1 (Hyal-1) (EC 3.2.1.35) (Hyaluronoglucosaminidase-1) Bos taurus (Bovine) carbohydrate metabolic process [GO:0005975]; cartilage development [GO:0051216]; cellular response to interleukin-1 [GO:0071347]; cellular response to pH [GO:0071467]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to UV-B [GO:0071493]; hyaluronan biosynthetic process [GO:0030213]; hyaluronan catabolic process [GO:0030214]; hyaluronan metabolic process [GO:0030212]; inflammatory response [GO:0006954]; negative regulation of cell growth [GO:0030308]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of growth [GO:0045927]; positive regulation of hyaluranon cable assembly [GO:1900106]; response to antibiotic [GO:0046677]; response to reactive oxygen species [GO:0000302]; response to virus [GO:0009615] GO:0000302; GO:0004415; GO:0005615; GO:0005737; GO:0005764; GO:0005975; GO:0006954; GO:0009615; GO:0010634; GO:0030212; GO:0030213; GO:0030214; GO:0030307; GO:0030308; GO:0031410; GO:0036117; GO:0036120; GO:0045766; GO:0045785; GO:0045927; GO:0046677; GO:0050501; GO:0050679; GO:0051216; GO:0071347; GO:0071467; GO:0071493; GO:1900087; GO:1900106 43192 XR_003824640.2 81 82 56 117 94 NA NA NA NA NA NA 43193 XR_003825917.1 5 31 23 9 29 NA NA NA NA NA NA 43194 XM_044320411.1 37 4 4 53 25 NA NA NA NA NA NA 43195 XR_006395518.1 34 15 10 1 10 NA NA NA NA NA NA 43196 XM_029340390.2 273 2 0 0 0 E9QAT4 1.14e-45 Protein transport protein Sec16A (SEC16 homolog A) (p250) Mus musculus (Mouse) autophagy [GO:0006914]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; Golgi to plasma membrane transport [GO:0006893]; protein exit from endoplasmic reticulum [GO:0032527]; protein localization to endoplasmic reticulum exit site [GO:0070973]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; response to endoplasmic reticulum stress [GO:0034976] GO:0000139; GO:0005789; GO:0005829; GO:0006888; GO:0006893; GO:0006914; GO:0007029; GO:0007030; GO:0012507; GO:0031090; GO:0032527; GO:0034976; GO:0048208; GO:0048471; GO:0050821; GO:0070971; GO:0070973; GO:0072659 43197 XM_029353043.2 0 15 6 0 0 F1R332 4.41e-24 Galanin receptor 2a Danio rerio (Zebrafish) (Brachydanio rerio) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; neuropeptide signaling pathway [GO:0007218] GO:0004966; GO:0005886; GO:0007188; GO:0007218; GO:0008528 43198 XR_006391972.1 110 15 14 0 0 NA NA NA NA NA NA 43199 XM_044320169.1 113 41 28 108 211 NA NA NA NA NA NA 43200 XM_029337519.2 485 507 414 531 702 Q4TZY1 4.1e-104 ATP-sensitive inward rectifier potassium channel 12 (Potassium channel, inwardly rectifying subfamily J member 12) Bos taurus (Bovine) potassium ion import across plasma membrane [GO:1990573]; potassium ion transport [GO:0006813]; protein homotetramerization [GO:0051289]; regulation of ion transmembrane transport [GO:0034765] GO:0005242; GO:0005886; GO:0006813; GO:0016020; GO:0034765; GO:0051289; GO:1990573 43201 XM_044322116.1 196 97 208 171 432 Q9Y2G8 2.89e-92 DnaJ homolog subfamily C member 16 Homo sapiens (Human) NA GO:0016020 43202 XM_029357683.2 260 195 246 31 282 Q5ZJU4 2.63e-42 Ubiquitin-related modifier 1 Gallus gallus (Chicken) protein urmylation [GO:0032447]; tRNA thio-modification [GO:0034227]; tRNA wobble uridine modification [GO:0002098] GO:0002098; GO:0005634; GO:0005829; GO:0031386; GO:0032447; GO:0034227 43203 XM_044320751.1 9 71 46 85 9 NA NA NA NA NA NA 43204 XM_029351608.2 94232 66563 65385 49299 20418 NA NA NA NA NA NA 43205 XR_006395266.1 9 18 15 24 46 NA NA NA NA NA NA 43206 XM_029339096.2 119 223 105 142 181 Q5ZI74 0 ATP-dependent RNA helicase DHX30 (EC 3.6.4.13) (DEAH box protein 30) Gallus gallus (Chicken) central nervous system development [GO:0007417]; ribosome biogenesis [GO:0042254] GO:0003682; GO:0003723; GO:0003724; GO:0005524; GO:0005737; GO:0005739; GO:0007417; GO:0016887; GO:0042254; GO:0042645 43207 XM_044328603.1 9 1 0 6 34 NA NA NA NA NA NA 43208 XR_006393742.1 490 480 230 245 295 NA NA NA NA NA NA 43209 XM_044314519.1 1 0 3 0 8 NA NA NA NA NA NA 43210 XM_029358653.2 107 139 199 64 189 Q71B07 0 Probable C-mannosyltransferase DPY19L3 (EC 2.4.1.-) (Dpy-19-like protein 3) (Protein dpy-19 homolog 3) Mus musculus (Mouse) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan [GO:0018406] GO:0000030; GO:0005637; GO:0018406 43211 XM_044320362.1 0 1 0 45 39 NA NA NA NA NA NA 43212 XR_006393381.1 32 6 0 0 25 NA NA NA NA NA NA 43213 XM_029328203.2 10 21 10 29 54 NA NA NA NA NA NA 43214 XM_029332921.2 423 406 385 616 522 Q6GVH4 2.38e-162 Gametogenetin-binding protein 2 (Protein ZNF403) Gallus gallus (Chicken) cell differentiation [GO:0030154]; spermatogenesis [GO:0007283] GO:0005634; GO:0005737; GO:0007283; GO:0030154 43215 XM_029332692.2 259 189 138 180 245 NA NA NA NA NA NA 43216 XM_029337763.2 75 2581 1037 3968 3265 Q8IVG5 9.48e-85 Sterile alpha motif domain-containing protein 9-like (SAM domain-containing protein 9-like) Homo sapiens (Human) NA GO:0005737; GO:0005739; GO:0005769 43217 XM_044310460.1 54 135 52 246 122 NA NA NA NA NA NA 43218 XM_029328732.2 0 262 636 0 159 NA NA NA NA NA NA 43219 XM_029329950.2 180 0 57 114 22 Q16445 1.29e-57 Gamma-aminobutyric acid receptor subunit alpha-6 (GABA(A) receptor subunit alpha-6) Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid signaling pathway [GO:0007214]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; regulation of postsynaptic membrane potential [GO:0060078]; signal transduction [GO:0007165]; synaptic transmission, GABAergic [GO:0051932] GO:0004890; GO:0005231; GO:0005237; GO:0005886; GO:0007165; GO:0007214; GO:0007268; GO:0008503; GO:0022851; GO:0030594; GO:0032590; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051932; GO:0060078; GO:0098794; GO:0099192; GO:1902476; GO:1902711; GO:1904315 43220 XM_044315931.1 0 72 88 30 68 Q5TEA3 0 Dynein axonemal assembly factor 9 (DNAAF9) Homo sapiens (Human) NA NA 43221 XM_044311190.1 63 0 0 25 16 D3ZR10 2.37e-26 Doublecortin domain-containing protein 2 Rattus norvegicus (Rat) cilium assembly [GO:0060271]; dendrite morphogenesis [GO:0048813]; intracellular signal transduction [GO:0035556]; neuron migration [GO:0001764]; neuronal action potential [GO:0019228]; positive regulation of smoothened signaling pathway [GO:0045880]; regulation of cilium assembly [GO:1902017]; regulation of Wnt signaling pathway [GO:0030111]; sensory perception of sound [GO:0007605]; synaptic transmission, glutamatergic [GO:0035249]; visual learning [GO:0008542] GO:0001764; GO:0005737; GO:0005815; GO:0005829; GO:0005856; GO:0005874; GO:0005929; GO:0005930; GO:0007605; GO:0008542; GO:0019228; GO:0019894; GO:0030111; GO:0034451; GO:0035249; GO:0035556; GO:0045202; GO:0045880; GO:0048813; GO:0060091; GO:0060271; GO:0072686; GO:1902017 43222 XM_029352444.2 65 19 60 86 31 NA NA NA NA NA NA 43223 XM_044322137.1 218 172 37 382 0 Q8NB59 1.51e-31 Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV) Homo sapiens (Human) NA GO:0005543; GO:0016020 43224 XR_003823471.2 4 0 2 4 7 NA NA NA NA NA NA 43225 XR_006394726.1 878 1079 281 625 183 Q5T7P8 4.9e-25 Synaptotagmin-6 (Synaptotagmin VI) (SytVI) Homo sapiens (Human) acrosomal vesicle exocytosis [GO:0060478]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; vesicle-mediated transport [GO:0016192] GO:0000149; GO:0001786; GO:0005509; GO:0005829; GO:0005886; GO:0014059; GO:0016020; GO:0016192; GO:0017156; GO:0017158; GO:0019898; GO:0019905; GO:0030276; GO:0030672; GO:0042803; GO:0060478; GO:0070382; GO:0071277; GO:0097038 43226 XR_006394726.1 878 1079 281 625 183 Q5T7P8 4.9e-25 Synaptotagmin-6 (Synaptotagmin VI) (SytVI) Homo sapiens (Human) acrosomal vesicle exocytosis [GO:0060478]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; vesicle-mediated transport [GO:0016192] GO:0000149; GO:0001786; GO:0005509; GO:0005829; GO:0005886; GO:0014059; GO:0016020; GO:0016192; GO:0017156; GO:0017158; GO:0019898; GO:0019905; GO:0030276; GO:0030672; GO:0042803; GO:0060478; GO:0070382; GO:0071277; GO:0097038 43227 XR_006394726.1 878 1079 281 625 183 Q5T7P8 4.9e-25 Synaptotagmin-6 (Synaptotagmin VI) (SytVI) Homo sapiens (Human) acrosomal vesicle exocytosis [GO:0060478]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; vesicle-mediated transport [GO:0016192] GO:0000149; GO:0001786; GO:0005509; GO:0005829; GO:0005886; GO:0014059; GO:0016020; GO:0016192; GO:0017156; GO:0017158; GO:0019898; GO:0019905; GO:0030276; GO:0030672; GO:0042803; GO:0060478; GO:0070382; GO:0071277; GO:0097038 43228 XR_003826978.2 257 262 242 207 154 NA NA NA NA NA NA 43229 XM_029330724.2 800 358 333 707 700 Q9CY64 4.18e-36 Biliverdin reductase A (BVR A) (EC 1.3.1.24) (Biliverdin-IX alpha-reductase) Mus musculus (Mouse) heme catabolic process [GO:0042167] GO:0000166; GO:0004074; GO:0005829; GO:0008270; GO:0042167; GO:0106276; GO:0106277 43230 XR_006391887.1 33 41 20 27 39 NA NA NA NA NA NA 43231 XM_029333160.2 931 375 77 237 17 NA NA NA NA NA NA 43232 XM_029348404.2 2495 1310 1311 1519 1692 D3ZGS3 0 Inositol polyphosphate 5-phosphatase OCRL (EC 3.1.3.36) (EC 3.1.3.56) (Inositol polyphosphate 5-phosphatase OCRL-1) (OCRL-1) (Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase) (EC 3.1.3.86) Rattus norvegicus (Rat) cilium assembly [GO:0060271]; in utero embryonic development [GO:0001701]; inositol phosphate dephosphorylation [GO:0046855]; phosphatidylinositol dephosphorylation [GO:0046856]; regulation of GTPase activity [GO:0043087]; signal transduction [GO:0007165] GO:0001701; GO:0001750; GO:0004439; GO:0004445; GO:0005096; GO:0005634; GO:0005737; GO:0005769; GO:0005802; GO:0005886; GO:0005905; GO:0007165; GO:0016020; GO:0030136; GO:0030670; GO:0031267; GO:0031901; GO:0034485; GO:0043087; GO:0046855; GO:0046856; GO:0052658; GO:0052659; GO:0052745; GO:0060271 43233 XM_029350936.2 2069 3634 1072 1972 1348 NA NA NA NA NA NA 43234 XM_029355387.2 8 13 5 19 0 NA NA NA NA NA NA 43235 XM_029343788.2 2890 2056 1006 2039 1726 NA NA NA NA NA NA 43236 XM_044308316.1 94 154 30 138 266 Q80XJ3 1.59e-61 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 43237 XM_044308316.1 94 154 30 138 266 Q80XJ3 1.68e-56 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 43238 XM_044308316.1 94 154 30 138 266 Q80XJ3 2.78e-55 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 43239 XM_044308316.1 94 154 30 138 266 Q80XJ3 1.4e-54 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 43240 XM_044308316.1 94 154 30 138 266 Q80XJ3 1.05e-52 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 43241 XM_044308316.1 94 154 30 138 266 Q80XJ3 6.84e-48 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 43242 XM_044308316.1 94 154 30 138 266 Q80XJ3 1.02e-45 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 43243 XM_044308316.1 94 154 30 138 266 Q80XJ3 1.48e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 43244 XM_044308316.1 94 154 30 138 266 Q80XJ3 2.76e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 43245 XM_044326622.1 0 3 0 6 0 NA NA NA NA NA NA 43246 XM_044311774.1 17 8 27 138 147 NA NA NA NA NA NA 43247 XM_029340141.2 80124 63862 35928 94990 68668 Q00613 1.42e-59 Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1) Homo sapiens (Human) cellular response to angiotensin [GO:1904385]; cellular response to cadmium ion [GO:0071276]; cellular response to copper ion [GO:0071280]; cellular response to diamide [GO:0072738]; cellular response to estradiol stimulus [GO:0071392]; cellular response to gamma radiation [GO:0071480]; cellular response to heat [GO:0034605]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to L-glutamine [GO:1904845]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nitroglycerin [GO:1904843]; cellular response to potassium ion [GO:0035865]; cellular response to sodium arsenite [GO:1903936]; cellular response to unfolded protein [GO:0034620]; cellular response to xenobiotic stimulus [GO:0071466]; defense response [GO:0006952]; DNA repair [GO:0006281]; MAPK cascade [GO:0000165]; mRNA processing [GO:0006397]; mRNA transcription [GO:0009299]; mRNA transport [GO:0051028]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of double-strand break repair via nonhomologous end joining [GO:2001033]; negative regulation of gene expression [GO:0010629]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of neuron death [GO:1901215]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of apoptotic DNA fragmentation [GO:1902512]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of gene expression [GO:0010628]; positive regulation of inclusion body assembly [GO:0090261]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of microtubule binding [GO:1904528]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of mRNA polyadenylation [GO:1900365]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein-containing complex assembly [GO:0065003]; regulation of cellular response to heat [GO:1900034]; regulation of transcription by RNA polymerase II [GO:0006357]; response to activity [GO:0014823]; response to hypobaric hypoxia [GO:1990910]; response to nutrient [GO:0007584]; response to psychosocial stress [GO:1990911]; response to testosterone [GO:0033574] GO:0000122; GO:0000165; GO:0000776; GO:0000785; GO:0000791; GO:0000792; GO:0000976; GO:0000978; GO:0000981; GO:0001162; GO:0001227; GO:0001228; GO:0003677; GO:0003700; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0005829; GO:0006281; GO:0006357; GO:0006397; GO:0006952; GO:0007584; GO:0009299; GO:0010628; GO:0010629; GO:0010667; GO:0014823; GO:0016605; GO:0019901; GO:0031072; GO:0031333; GO:0031490; GO:0033574; GO:0034605; GO:0034620; GO:0035865; GO:0042531; GO:0042802; GO:0043280; GO:0043565; GO:0043621; GO:0045651; GO:0045931; GO:0045944; GO:0046982; GO:0048471; GO:0051028; GO:0051091; GO:0051879; GO:0061770; GO:0065003; GO:0070301; GO:0071222; GO:0071276; GO:0071280; GO:0071392; GO:0071466; GO:0071480; GO:0072738; GO:0090084; GO:0090261; GO:0097165; GO:0097431; GO:0097677; GO:0098847; GO:0101031; GO:0120162; GO:0140296; GO:1900034; GO:1900365; GO:1901215; GO:1902512; GO:1903936; GO:1904385; GO:1904528; GO:1904843; GO:1904845; GO:1990837; GO:1990841; GO:1990904; GO:1990910; GO:1990911; GO:2001033 43248 XM_029338404.2 223 240 94 158 343 P95329 1.27e-179 Malate synthase (EC 2.3.3.9) Myxococcus xanthus (strain DK1622) glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099] GO:0004474; GO:0005737; GO:0006097; GO:0006099 43249 XM_044318109.1 366 376 230 251 487 NA NA NA NA NA NA 43250 XM_029343999.2 1845 1277 783 1969 1273 Q6E2N3 1.89e-58 E3 ubiquitin-protein ligase TRIM33 (EC 2.3.2.27) (Ectodermin homolog) (Protein moonshine) (RING-type E3 ubiquitin transferase TRIM33) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33) Danio rerio (Zebrafish) (Brachydanio rerio) developmental pigmentation [GO:0048066]; embryonic hemopoiesis [GO:0035162]; erythrocyte differentiation [GO:0030218]; fin development [GO:0033333]; macrophage chemotaxis [GO:0048246]; macrophage migration [GO:1905517]; neutrophil chemotaxis [GO:0030593]; neutrophil migration [GO:1990266]; post-embryonic hemopoiesis [GO:0035166]; primitive hemopoiesis [GO:0060215]; protein ubiquitination [GO:0016567]; regulation of transcription elongation by RNA polymerase II [GO:0034243] GO:0003677; GO:0005634; GO:0008270; GO:0016567; GO:0016740; GO:0030218; GO:0030593; GO:0033333; GO:0034243; GO:0035162; GO:0035166; GO:0048066; GO:0048246; GO:0060215; GO:1905517; GO:1990266 43251 XM_029343999.2 1845 1277 783 1969 1273 Q6E2N3 5.1e-42 E3 ubiquitin-protein ligase TRIM33 (EC 2.3.2.27) (Ectodermin homolog) (Protein moonshine) (RING-type E3 ubiquitin transferase TRIM33) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33) Danio rerio (Zebrafish) (Brachydanio rerio) developmental pigmentation [GO:0048066]; embryonic hemopoiesis [GO:0035162]; erythrocyte differentiation [GO:0030218]; fin development [GO:0033333]; macrophage chemotaxis [GO:0048246]; macrophage migration [GO:1905517]; neutrophil chemotaxis [GO:0030593]; neutrophil migration [GO:1990266]; post-embryonic hemopoiesis [GO:0035166]; primitive hemopoiesis [GO:0060215]; protein ubiquitination [GO:0016567]; regulation of transcription elongation by RNA polymerase II [GO:0034243] GO:0003677; GO:0005634; GO:0008270; GO:0016567; GO:0016740; GO:0030218; GO:0030593; GO:0033333; GO:0034243; GO:0035162; GO:0035166; GO:0048066; GO:0048246; GO:0060215; GO:1905517; GO:1990266 43252 XR_006393843.1 166 131 40 83 87 NA NA NA NA NA NA 43253 XR_006392658.1 0 0 39 0 59 Q5NCX5 2.8e-29 Neuralized-like protein 4 Mus musculus (Mouse) NA GO:0005737; GO:0005814; GO:0061630 43254 XR_006392658.1 0 0 39 0 59 Q5NCX5 5.32e-25 Neuralized-like protein 4 Mus musculus (Mouse) NA GO:0005737; GO:0005814; GO:0061630 43255 XR_006392658.1 0 0 39 0 59 Q5NCX5 2.18e-22 Neuralized-like protein 4 Mus musculus (Mouse) NA GO:0005737; GO:0005814; GO:0061630 43256 XR_006392658.1 0 0 39 0 59 Q5NCX5 4e-21 Neuralized-like protein 4 Mus musculus (Mouse) NA GO:0005737; GO:0005814; GO:0061630 43257 XM_029340939.2 0 4 2 3 38 NA NA NA NA NA NA 43258 XM_044327528.1 7 0 9 0 0 A2RUC4 1.32e-142 tRNA wybutosine-synthesizing protein 5 (hTYW5) (tRNA yW-synthesizing protein 5) (EC 1.14.11.42) (tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-C(2))-hydroxylase) Homo sapiens (Human) wybutosine biosynthetic process [GO:0031591] GO:0000049; GO:0005506; GO:0005737; GO:0016706; GO:0031591; GO:0042803; GO:0102524 43259 XM_044318816.1 159 148 99 97 25 NA NA NA NA NA NA 43260 XR_006391470.1 69 66 41 64 59 NA NA NA NA NA NA 43261 XR_003823018.1 2 7 2 9 4 NA NA NA NA NA NA 43262 XM_029338526.2 101 36 31 107 67 NA NA NA NA NA NA 43263 XR_006397251.1 267 872 79 78 58 NA NA NA NA NA NA 43264 XM_029352231.2 158 80 33 64 78 NA NA NA NA NA NA 43265 XM_029348588.2 36 7 29 0 5 P24369 4.68e-67 Peptidyl-prolyl cis-trans isomerase B (PPIase B) (EC 5.2.1.8) (CYP-S1) (Cyclophilin B) (Rotamase B) (S-cyclophilin) (SCYLP) Mus musculus (Mouse) bone development [GO:0060348]; chaperone-mediated protein folding [GO:0061077]; neutrophil chemotaxis [GO:0030593]; positive regulation by host of viral genome replication [GO:0044829]; positive regulation by host of viral process [GO:0044794]; positive regulation of multicellular organism growth [GO:0040018]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821] GO:0000413; GO:0003755; GO:0005654; GO:0005737; GO:0005783; GO:0005788; GO:0005790; GO:0006457; GO:0016018; GO:0030593; GO:0032991; GO:0034663; GO:0040018; GO:0042470; GO:0043231; GO:0044794; GO:0044829; GO:0048471; GO:0050821; GO:0060348; GO:0061077; GO:0070063 43266 XM_029336988.2 5575 4726 2737 6915 5345 NA NA NA NA NA NA 43267 XM_029349343.2 231 18 0 0 0 NA NA NA NA NA NA 43268 XR_006395833.1 89 117 62 101 81 NA NA NA NA NA NA 43269 XM_029343448.2 1727 2569 1025 2502 1286 Q58CU3 1.24e-93 HSPB1-associated protein 1 (27 kDa heat shock protein-associated protein 1) Bos taurus (Bovine) NA GO:0005737; GO:0016706 43270 XR_006394629.1 174 47 35 46 40 NA NA NA NA NA NA 43271 XM_029345711.2 247 0 0 0 0 NA NA NA NA NA NA 43272 XM_044313810.1 14 18 25 1 27 NA NA NA NA NA NA 43273 XM_029339310.2 567 601 403 881 638 NA NA NA NA NA NA 43274 XM_044321014.1 392 142 116 164 206 P37235 4.4e-61 Hippocalcin-like protein 1 (Calcium-binding protein BDR-1) (HLP2) (Visinin-like protein 3) (VILIP-3) Homo sapiens (Human) NA GO:0005509; GO:0016020 43275 XR_006393288.1 31 11 18 39 47 F8J2D3 2.71e-26 Phospholipase-B 81 (PLB) (EC 3.1.1.-) Drysdalia coronoides (White-lipped snake) (Hoplocephalus coronoides) hemolysis in another organism [GO:0044179]; lipid catabolic process [GO:0016042] GO:0004620; GO:0005576; GO:0016042; GO:0044179; GO:0090729 43276 XR_006391955.1 0 0 0 0 16 NA NA NA NA NA NA 43277 XR_006392238.1 27 76 14 37 11 NA NA NA NA NA NA 43278 XM_044315305.1 1 0 0 0 10 NA NA NA NA NA NA 43279 XM_044319700.1 20 7 0 21 31 E7FAM5 1.16e-90 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 43280 XR_003826460.2 2067 1565 1004 1044 863 Q6PBT6 6.62e-25 GTP cyclohydrolase 1 feedback regulatory protein (GFRP) (GTP cyclohydrolase I feedback regulatory protein) Danio rerio (Zebrafish) (Brachydanio rerio) negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105] GO:0005634; GO:0005737; GO:0005829; GO:0009890; GO:0031965; GO:0043105; GO:0044549 43281 XM_044317936.1 0 25 73 44 97 P38571 5.31e-123 Lysosomal acid lipase/cholesteryl ester hydrolase (Acid cholesteryl ester hydrolase) (LAL) (EC 3.1.1.13) (Cholesteryl esterase) (Lipase A) (Sterol esterase) Homo sapiens (Human) cell morphogenesis [GO:0000902]; epithelial cell proliferation [GO:0050673]; homeostasis of number of cells within a tissue [GO:0048873]; inflammatory response [GO:0006954]; lipid catabolic process [GO:0016042]; low-density lipoprotein particle clearance [GO:0034383]; lung development [GO:0030324]; macrophage homeostasis [GO:0061519]; sterol metabolic process [GO:0016125]; tissue remodeling [GO:0048771] GO:0000902; GO:0001650; GO:0004771; GO:0005654; GO:0005764; GO:0005829; GO:0006954; GO:0016042; GO:0016125; GO:0016298; GO:0030324; GO:0034383; GO:0043202; GO:0043231; GO:0048771; GO:0048873; GO:0050673; GO:0061519 43282 XM_029327680.2 0 0 0 16 0 Q495W5 9.42e-110 Alpha-(1,3)-fucosyltransferase 11 (EC 2.4.1.-) (Fucosyltransferase XI) (Fuc-TXI) (FucT-XI) (Galactoside 3-L-fucosyltransferase 11) (Fucosyltransferase 11) Homo sapiens (Human) fucosylation [GO:0036065]; N-glycan fucosylation [GO:0036071]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0008417; GO:0032580; GO:0036065; GO:0036071; GO:0046920 43283 XM_029328839.2 1001 604 349 739 785 Q9H583 0 HEAT repeat-containing protein 1 (Protein BAP28) (U3 small nucleolar RNA-associated protein 10 homolog) [Cleaved into: HEAT repeat-containing protein 1, N-terminally processed] Homo sapiens (Human) maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; positive regulation of rRNA processing [GO:2000234]; positive regulation of transcription by RNA polymerase I [GO:0045943] GO:0000462; GO:0001650; GO:0003723; GO:0005654; GO:0005730; GO:0005739; GO:0016020; GO:0030515; GO:0030686; GO:0032040; GO:0034455; GO:0045943; GO:2000234 43284 XM_029332742.2 650 436 523 561 482 Q0P457 1.29e-114 Protein KTI12 homolog Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005524 43285 XM_029340880.2 2129 2019 1134 1701 1142 NA NA NA NA NA NA 43286 XM_044322185.1 37 58 40 50 0 NA NA NA NA NA NA 43287 XM_029345838.2 724 594 423 529 451 Q20201 8.86e-21 Transcription factor sox-3 Caenorhabditis elegans anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; neuron differentiation [GO:0030182]; regulation of DNA-templated transcription [GO:0006355] GO:0000978; GO:0000981; GO:0005634; GO:0006355; GO:0009653; GO:0030154; GO:0030182; GO:0043565 43288 XM_029334678.2 14 56 52 161 126 NA NA NA NA NA NA 43289 XM_029341525.2 0 0 0 50 0 C3ZQF9 1.39e-25 QRFP-like peptide receptor Branchiostoma floridae (Florida lancelet) (Amphioxus) cellular response to peptide [GO:1901653]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:1901653 43290 XM_044324294.1 1619 423 357 1356 1147 P60882 0 Multiple epidermal growth factor-like domains protein 8 (Multiple EGF-like domains protein 8) (Epidermal growth factor-like protein 4) (EGF-like protein 4) Mus musculus (Mouse) animal organ morphogenesis [GO:0009887]; BMP signaling pathway [GO:0030509]; cell migration involved in gastrulation [GO:0042074]; coronary vasculature development [GO:0060976]; craniofacial suture morphogenesis [GO:0097094]; determination of digestive tract left/right asymmetry [GO:0071907]; determination of heart left/right asymmetry [GO:0061371]; determination of left/right symmetry [GO:0007368]; embryonic heart tube left/right pattern formation [GO:0060971]; embryonic heart tube morphogenesis [GO:0003143]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; epiboly involved in gastrulation with mouth forming second [GO:0055113]; fasciculation of sensory neuron axon [GO:0097155]; left/right pattern formation [GO:0060972]; limb morphogenesis [GO:0035108]; negative regulation of smoothened signaling pathway [GO:0045879]; positive regulation of axon extension involved in axon guidance [GO:0048842]; regulation of gene expression [GO:0010468]; tissue development [GO:0009888] GO:0003143; GO:0005509; GO:0005634; GO:0007368; GO:0009887; GO:0009888; GO:0010468; GO:0016020; GO:0030326; GO:0030509; GO:0035108; GO:0042074; GO:0045879; GO:0048704; GO:0048842; GO:0055113; GO:0060971; GO:0060972; GO:0060976; GO:0061371; GO:0071907; GO:0097094; GO:0097155 43291 XM_044324294.1 1619 423 357 1356 1147 P60882 1.89e-116 Multiple epidermal growth factor-like domains protein 8 (Multiple EGF-like domains protein 8) (Epidermal growth factor-like protein 4) (EGF-like protein 4) Mus musculus (Mouse) animal organ morphogenesis [GO:0009887]; BMP signaling pathway [GO:0030509]; cell migration involved in gastrulation [GO:0042074]; coronary vasculature development [GO:0060976]; craniofacial suture morphogenesis [GO:0097094]; determination of digestive tract left/right asymmetry [GO:0071907]; determination of heart left/right asymmetry [GO:0061371]; determination of left/right symmetry [GO:0007368]; embryonic heart tube left/right pattern formation [GO:0060971]; embryonic heart tube morphogenesis [GO:0003143]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; epiboly involved in gastrulation with mouth forming second [GO:0055113]; fasciculation of sensory neuron axon [GO:0097155]; left/right pattern formation [GO:0060972]; limb morphogenesis [GO:0035108]; negative regulation of smoothened signaling pathway [GO:0045879]; positive regulation of axon extension involved in axon guidance [GO:0048842]; regulation of gene expression [GO:0010468]; tissue development [GO:0009888] GO:0003143; GO:0005509; GO:0005634; GO:0007368; GO:0009887; GO:0009888; GO:0010468; GO:0016020; GO:0030326; GO:0030509; GO:0035108; GO:0042074; GO:0045879; GO:0048704; GO:0048842; GO:0055113; GO:0060971; GO:0060972; GO:0060976; GO:0061371; GO:0071907; GO:0097094; GO:0097155 43292 XM_044324294.1 1619 423 357 1356 1147 P60882 2.02e-38 Multiple epidermal growth factor-like domains protein 8 (Multiple EGF-like domains protein 8) (Epidermal growth factor-like protein 4) (EGF-like protein 4) Mus musculus (Mouse) animal organ morphogenesis [GO:0009887]; BMP signaling pathway [GO:0030509]; cell migration involved in gastrulation [GO:0042074]; coronary vasculature development [GO:0060976]; craniofacial suture morphogenesis [GO:0097094]; determination of digestive tract left/right asymmetry [GO:0071907]; determination of heart left/right asymmetry [GO:0061371]; determination of left/right symmetry [GO:0007368]; embryonic heart tube left/right pattern formation [GO:0060971]; embryonic heart tube morphogenesis [GO:0003143]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; epiboly involved in gastrulation with mouth forming second [GO:0055113]; fasciculation of sensory neuron axon [GO:0097155]; left/right pattern formation [GO:0060972]; limb morphogenesis [GO:0035108]; negative regulation of smoothened signaling pathway [GO:0045879]; positive regulation of axon extension involved in axon guidance [GO:0048842]; regulation of gene expression [GO:0010468]; tissue development [GO:0009888] GO:0003143; GO:0005509; GO:0005634; GO:0007368; GO:0009887; GO:0009888; GO:0010468; GO:0016020; GO:0030326; GO:0030509; GO:0035108; GO:0042074; GO:0045879; GO:0048704; GO:0048842; GO:0055113; GO:0060971; GO:0060972; GO:0060976; GO:0061371; GO:0071907; GO:0097094; GO:0097155 43293 XM_044324294.1 1619 423 357 1356 1147 P60882 5.95e-28 Multiple epidermal growth factor-like domains protein 8 (Multiple EGF-like domains protein 8) (Epidermal growth factor-like protein 4) (EGF-like protein 4) Mus musculus (Mouse) animal organ morphogenesis [GO:0009887]; BMP signaling pathway [GO:0030509]; cell migration involved in gastrulation [GO:0042074]; coronary vasculature development [GO:0060976]; craniofacial suture morphogenesis [GO:0097094]; determination of digestive tract left/right asymmetry [GO:0071907]; determination of heart left/right asymmetry [GO:0061371]; determination of left/right symmetry [GO:0007368]; embryonic heart tube left/right pattern formation [GO:0060971]; embryonic heart tube morphogenesis [GO:0003143]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; epiboly involved in gastrulation with mouth forming second [GO:0055113]; fasciculation of sensory neuron axon [GO:0097155]; left/right pattern formation [GO:0060972]; limb morphogenesis [GO:0035108]; negative regulation of smoothened signaling pathway [GO:0045879]; positive regulation of axon extension involved in axon guidance [GO:0048842]; regulation of gene expression [GO:0010468]; tissue development [GO:0009888] GO:0003143; GO:0005509; GO:0005634; GO:0007368; GO:0009887; GO:0009888; GO:0010468; GO:0016020; GO:0030326; GO:0030509; GO:0035108; GO:0042074; GO:0045879; GO:0048704; GO:0048842; GO:0055113; GO:0060971; GO:0060972; GO:0060976; GO:0061371; GO:0071907; GO:0097094; GO:0097155 43294 XM_029337833.2 15 5 4 5 34 Q6RI86 3.2e-98 Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Wasabi receptor) Rattus norvegicus (Rat) calcium ion transmembrane import into cytosol [GO:0097553]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cell surface receptor signaling pathway [GO:0007166]; cellular calcium ion homeostasis [GO:0006874]; cellular response to caffeine [GO:0071313]; cellular response to carbon dioxide [GO:0071244]; cellular response to cold [GO:0070417]; cellular response to heat [GO:0034605]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to organic substance [GO:0071310]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; ion transmembrane transport [GO:0034220]; positive regulation of anion transport [GO:1903793]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of sensory perception of pain [GO:1904058]; protein homotetramerization [GO:0051289]; regulation of blood circulation [GO:1903522]; regulation of neuronal action potential [GO:0098908]; response to cold [GO:0009409]; response to hydrogen peroxide [GO:0042542]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; sensory perception of pain [GO:0019233]; thermoception [GO:0050955]; transmembrane transport [GO:0055085]; urinary bladder smooth muscle contraction [GO:0014832] GO:0005216; GO:0005245; GO:0005262; GO:0005886; GO:0006816; GO:0006874; GO:0007166; GO:0009409; GO:0009410; GO:0010033; GO:0014070; GO:0014832; GO:0015267; GO:0015278; GO:0016324; GO:0019233; GO:0030424; GO:0032421; GO:0034220; GO:0034605; GO:0035774; GO:0042542; GO:0042802; GO:0048265; GO:0050955; GO:0050966; GO:0050968; GO:0050974; GO:0051289; GO:0055085; GO:0070301; GO:0070417; GO:0070588; GO:0071244; GO:0071310; GO:0071313; GO:0097553; GO:0097604; GO:0098908; GO:1903522; GO:1903793; GO:1904058; GO:1990760 43295 XM_044310787.1 92 41 7 63 10 Q96AY4 2.19e-119 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 43296 XM_044310787.1 92 41 7 63 10 Q96AY4 3.77e-69 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 43297 XM_044310787.1 92 41 7 63 10 Q96AY4 2.18e-61 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 43298 XM_044310787.1 92 41 7 63 10 Q96AY4 2.11e-57 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 43299 XM_044310787.1 92 41 7 63 10 Q96AY4 7.88e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 43300 XR_006394327.1 216 964 9 188 177 NA NA NA NA NA NA 43301 XM_029329682.2 61 282 12 130 0 Q8BW96 7.63e-149 Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase I delta) (CaM-KI delta) (CaMKI delta) (CaM kinase ID) (CaMKI-like protein kinase) (CKLiK) (mCKLiK) Mus musculus (Mouse) inflammatory response [GO:0006954]; negative regulation of apoptotic process [GO:0043066]; nervous system development [GO:0007399]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of neuron projection development [GO:0010976]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of phagocytosis [GO:0050766]; positive regulation of respiratory burst [GO:0060267]; regulation of dendrite development [GO:0050773]; regulation of granulocyte chemotaxis [GO:0071622] GO:0004683; GO:0005516; GO:0005524; GO:0005634; GO:0005737; GO:0006954; GO:0007399; GO:0010976; GO:0018105; GO:0032793; GO:0043065; GO:0043066; GO:0050766; GO:0050773; GO:0060267; GO:0071622; GO:0090023; GO:0106310 43302 XM_044307557.1 3521 8406 1652 3886 1489 NA NA NA NA NA NA 43303 XR_003825447.1 505 283 262 179 292 NA NA NA NA NA NA 43304 XR_006393771.1 5 0 57 0 11 NA NA NA NA NA NA 43305 XR_006392768.1 288 92 322 365 289 NA NA NA NA NA NA 43306 XM_044310843.1 1339 233 481 940 761 P98088 8.61e-93 Mucin-5AC (MUC-5AC) (Gastric mucin) (Major airway glycoprotein) (Mucin-5 subtype AC, tracheobronchial) (Tracheobronchial mucin) (TBM) Homo sapiens (Human) phosphatidylinositol-mediated signaling [GO:0048015] GO:0005201; GO:0005615; GO:0005737; GO:0005796; GO:0005886; GO:0031012; GO:0048015; GO:0070062; GO:0070701 43307 XM_044310843.1 1339 233 481 940 761 P98088 2.47e-22 Mucin-5AC (MUC-5AC) (Gastric mucin) (Major airway glycoprotein) (Mucin-5 subtype AC, tracheobronchial) (Tracheobronchial mucin) (TBM) Homo sapiens (Human) phosphatidylinositol-mediated signaling [GO:0048015] GO:0005201; GO:0005615; GO:0005737; GO:0005796; GO:0005886; GO:0031012; GO:0048015; GO:0070062; GO:0070701 43308 XM_044324656.1 133 0 0 89 0 O15068 9.18e-153 Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2-transforming sequence-like protein) Homo sapiens (Human) intracellular signal transduction [GO:0035556]; positive regulation of Rho protein signal transduction [GO:0035025]; regulation of small GTPase mediated signal transduction [GO:0051056] GO:0005085; GO:0005615; GO:0005737; GO:0005829; GO:0005886; GO:0012505; GO:0019898; GO:0031234; GO:0035025; GO:0035091; GO:0035556; GO:0051056 43309 XM_029355516.2 6 4 0 0 0 Q8NFF2 7.98e-116 Sodium/potassium/calcium exchanger 4 (Na(+)/K(+)/Ca(2+)-exchange protein 4) (Solute carrier family 24 member 4) Homo sapiens (Human) amelogenesis [GO:0097186]; calcium ion export across plasma membrane [GO:1990034]; calcium ion homeostasis [GO:0055074]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; cellular response to high light intensity [GO:0071486]; cone photoresponse recovery [GO:0036368]; detection of chemical stimulus involved in sensory perception of smell [GO:0050911]; drinking behavior [GO:0042756]; enamel mineralization [GO:0070166]; ion transport [GO:0006811]; membrane repolarization [GO:0086009]; negative regulation of calcium-mediated signaling [GO:0050849]; olfactory nerve maturation [GO:0021630]; phototransduction [GO:0007602]; positive regulation of gene expression [GO:0010628]; potassium ion transmembrane transport [GO:0071805]; regulation of eating behavior [GO:1903998]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; regulation of signaling receptor activity [GO:0010469]; response to high light intensity [GO:0009644]; response to melanocyte-stimulating hormone [GO:1990680]; response to odorant [GO:1990834]; sensory perception of smell [GO:0007608]; sodium ion transmembrane transport [GO:0035725] GO:0005262; GO:0005516; GO:0005737; GO:0005886; GO:0006811; GO:0006874; GO:0007602; GO:0007608; GO:0008273; GO:0008277; GO:0009644; GO:0010469; GO:0010628; GO:0015293; GO:0016020; GO:0016324; GO:0021630; GO:0031982; GO:0035725; GO:0036368; GO:0042756; GO:0048306; GO:0050849; GO:0050911; GO:0055074; GO:0070166; GO:0070588; GO:0071486; GO:0071805; GO:0086009; GO:0097186; GO:0098703; GO:0120199; GO:1903998; GO:1990034; GO:1990680; GO:1990834 43310 XM_029349281.2 1286 508 579 797 972 Q28C33 8.01e-167 TBC1 domain family member 30 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA NA 43311 XM_044320092.1 1578 1431 865 1478 1239 NA NA NA NA NA NA 43312 XM_044310503.1 1 1 8 0 33 Q91ZV3 1.46e-28 Discoidin, CUB and LCCL domain-containing protein 2 (Endothelial and smooth muscle cell-derived neuropilin-like protein) Mus musculus (Mouse) negative regulation of cell growth [GO:0030308]; wound healing [GO:0042060] GO:0005886; GO:0009986; GO:0030308; GO:0038023; GO:0042060 43313 XM_029350676.2 2350 2306 1207 2102 1522 Q3ZBD0 2.26e-147 26S proteasome non-ATPase regulatory subunit 7 (26S proteasome regulatory subunit RPN8) Bos taurus (Bovine) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] GO:0000502; GO:0005838; GO:0008237; GO:0043161 43314 XM_044322057.1 85 317 252 88 120 Q28HM1 4.74e-79 Dimethyladenosine transferase 1, mitochondrial (EC 2.1.1.-) (Mitochondrial 12S rRNA dimethylase 1) (Mitochondrial transcription factor B1) (mtTFB1) (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0000179; GO:0003677; GO:0003723; GO:0005739 43315 XR_003826743.2 39 25 31 38 31 P58058 6.14e-27 NAD kinase (EC 2.7.1.23) (Poly(P)/ATP NAD kinase) Mus musculus (Mouse) NAD metabolic process [GO:0019674]; NADP biosynthetic process [GO:0006741]; phosphorylation [GO:0016310]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774] GO:0003951; GO:0005524; GO:0005829; GO:0006741; GO:0016310; GO:0019674; GO:0035774; GO:0046872 43316 XR_003826743.2 39 25 31 38 31 P58058 6.14e-27 NAD kinase (EC 2.7.1.23) (Poly(P)/ATP NAD kinase) Mus musculus (Mouse) NAD metabolic process [GO:0019674]; NADP biosynthetic process [GO:0006741]; phosphorylation [GO:0016310]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774] GO:0003951; GO:0005524; GO:0005829; GO:0006741; GO:0016310; GO:0019674; GO:0035774; GO:0046872 43317 XM_044312806.1 0 0 10 15 21 Q17RS7 2.01e-68 Flap endonuclease GEN homolog 1 (EC 3.1.-.-) Homo sapiens (Human) double-strand break repair via homologous recombination [GO:0000724]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; regulation of centrosome duplication [GO:0010824]; replication fork processing [GO:0031297]; resolution of mitotic recombination intermediates [GO:0071140]; resolution of recombination intermediates [GO:0071139] GO:0000287; GO:0000400; GO:0000724; GO:0005654; GO:0005813; GO:0008821; GO:0010824; GO:0017108; GO:0031297; GO:0042803; GO:0071139; GO:0071140; GO:0090267 43318 XM_044325779.1 8 5 3 11 9 Q8K3Z0 2.17e-34 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 43319 XR_006397774.1 451 405 263 484 424 NA NA NA NA NA NA 43320 XM_029348133.2 75 36 59 79 224 Q21565 2.97e-88 Putative ammonium transporter 3 Caenorhabditis elegans ammonium homeostasis [GO:0097272]; ammonium transmembrane transport [GO:0072488] GO:0005886; GO:0008519; GO:0072488; GO:0097272 43321 XR_006396038.1 179 5 26 12 149 NA NA NA NA NA NA 43322 XM_029342966.2 670 1346 502 1397 1130 O35093 1.18e-25 Mitochondrial import inner membrane translocase subunit Tim23 Rattus norvegicus (Rat) intracellular protein transport [GO:0006886]; positive regulation of protein processing [GO:0010954]; protein import into mitochondrial matrix [GO:0030150]; response to 3,3',5-triiodo-L-thyronine [GO:1905242] GO:0005739; GO:0005743; GO:0005744; GO:0005758; GO:0006886; GO:0008320; GO:0010954; GO:0030150; GO:0140494; GO:1905242 43323 XM_029333790.2 626 398 342 560 410 Q5S007 2.35e-64 Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin) Homo sapiens (Human) autophagy [GO:0006914]; calcium-mediated signaling [GO:0019722]; canonical Wnt signaling pathway [GO:0060070]; cellular response to dopamine [GO:1903351]; cellular response to manganese ion [GO:0071287]; cellular response to organic cyclic compound [GO:0071407]; cellular response to oxidative stress [GO:0034599]; cellular response to starvation [GO:0009267]; determination of adult lifespan [GO:0008340]; endocytosis [GO:0006897]; endoplasmic reticulum organization [GO:0007029]; excitatory postsynaptic potential [GO:0060079]; exploration behavior [GO:0035640]; Golgi organization [GO:0007030]; GTP metabolic process [GO:0046039]; intracellular distribution of mitochondria [GO:0048312]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; locomotory exploration behavior [GO:0035641]; lysosome organization [GO:0007040]; MAPK cascade [GO:0000165]; mitochondrion localization [GO:0051646]; mitochondrion organization [GO:0007005]; negative regulation of autophagosome assembly [GO:1902902]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of GTPase activity [GO:0034260]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of late endosome to lysosome transport [GO:1902823]; negative regulation of macroautophagy [GO:0016242]; negative regulation of neuron death [GO:1901215]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein binding [GO:0032091]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein processing [GO:0010955]; negative regulation of protein processing involved in protein targeting to mitochondrion [GO:1903217]; negative regulation of protein targeting to mitochondrion [GO:1903215]; negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation [GO:1903125]; neuromuscular junction development [GO:0007528]; neuron death [GO:0070997]; neuron projection arborization [GO:0140058]; neuron projection morphogenesis [GO:0048812]; olfactory bulb development [GO:0021772]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; phosphorylation [GO:0016310]; positive regulation of autophagy [GO:0010508]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of dopamine receptor signaling pathway [GO:0060161]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of programmed cell death [GO:0043068]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein autoubiquitination [GO:1902499]; positive regulation of protein binding [GO:0032092]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; positive regulation of tumor necrosis factor production [GO:0032760]; protein autophosphorylation [GO:0046777]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein localization to endoplasmic reticulum exit site [GO:0070973]; protein localization to mitochondrion [GO:0070585]; protein phosphorylation [GO:0006468]; reactive oxygen species metabolic process [GO:0072593]; regulation of autophagy [GO:0010506]; regulation of branching morphogenesis of a nerve [GO:2000172]; regulation of CAMKK-AMPK signaling cascade [GO:1905289]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of dopamine receptor signaling pathway [GO:0060159]; regulation of ER to Golgi vesicle-mediated transport [GO:0060628]; regulation of kidney size [GO:0035564]; regulation of locomotion [GO:0040012]; regulation of lysosomal lumen pH [GO:0035751]; regulation of membrane potential [GO:0042391]; regulation of mitochondrial depolarization [GO:0051900]; regulation of mitochondrial fission [GO:0090140]; regulation of neuroblast proliferation [GO:1902692]; regulation of neuron death [GO:1901214]; regulation of neuron maturation [GO:0014041]; regulation of protein kinase A signaling [GO:0010738]; regulation of protein stability [GO:0031647]; regulation of retrograde transport, endosome to Golgi [GO:1905279]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of synaptic vesicle exocytosis [GO:2000300]; regulation of synaptic vesicle transport [GO:1902803]; response to oxidative stress [GO:0006979]; signal transduction [GO:0007165]; spermatogenesis [GO:0007283]; striatum development [GO:0021756]; tangential migration from the subventricular zone to the olfactory bulb [GO:0022028]; Wnt signalosome assembly [GO:1904887] GO:0000139; GO:0000149; GO:0000165; GO:0000287; GO:0001933; GO:0001934; GO:0003779; GO:0003924; GO:0004672; GO:0004674; GO:0004706; GO:0004709; GO:0004722; GO:0005096; GO:0005524; GO:0005525; GO:0005615; GO:0005737; GO:0005739; GO:0005741; GO:0005743; GO:0005759; GO:0005764; GO:0005768; GO:0005783; GO:0005789; GO:0005794; GO:0005798; GO:0005802; GO:0005829; GO:0005886; GO:0005902; GO:0006468; GO:0006606; GO:0006897; GO:0006914; GO:0006979; GO:0007005; GO:0007029; GO:0007030; GO:0007040; GO:0007165; GO:0007254; GO:0007283; GO:0007528; GO:0008017; GO:0008104; GO:0008340; GO:0009267; GO:0010506; GO:0010508; GO:0010738; GO:0010955; GO:0010977; GO:0014041; GO:0015631; GO:0016234; GO:0016242; GO:0016301; GO:0016310; GO:0017075; GO:0018105; GO:0018107; GO:0019722; GO:0021756; GO:0021772; GO:0022028; GO:0030159; GO:0030276; GO:0030424; GO:0030425; GO:0030426; GO:0030672; GO:0031267; GO:0031398; GO:0031410; GO:0031647; GO:0031966; GO:0032091; GO:0032092; GO:0032436; GO:0032473; GO:0032760; GO:0032839; GO:0034211; GO:0034260; GO:0034599; GO:0035556; GO:0035564; GO:0035640; GO:0035641; GO:0035751; GO:0036479; GO:0039706; GO:0040012; GO:0042391; GO:0042802; GO:0042803; GO:0043005; GO:0043025; GO:0043068; GO:0043195; GO:0043204; GO:0043231; GO:0043406; GO:0044325; GO:0044753; GO:0044754; GO:0045121; GO:0045860; GO:0046039; GO:0046777; GO:0048312; GO:0048812; GO:0051018; GO:0051646; GO:0051770; GO:0051900; GO:0051966; GO:0060070; GO:0060079; GO:0060159; GO:0060161; GO:0060628; GO:0060828; GO:0061001; GO:0070062; GO:0070585; GO:0070971; GO:0070973; GO:0070997; GO:0071287; GO:0071407; GO:0072593; GO:0090140; GO:0090263; GO:0090394; GO:0097487; GO:0098794; GO:0098978; GO:0099400; GO:0099523; GO:0106310; GO:0140058; GO:1900244; GO:1901214; GO:1901215; GO:1901727; GO:1902236; GO:1902499; GO:1902692; GO:1902803; GO:1902823; GO:1902902; GO:1903125; GO:1903206; GO:1903215; GO:1903217; GO:1903351; GO:1903980; GO:1904713; GO:1904887; GO:1905279; GO:1905289; GO:1990904; GO:1990909; GO:2000172; GO:2000300 43324 XM_029333790.2 626 398 342 560 410 Q5S007 5.12e-53 Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin) Homo sapiens (Human) autophagy [GO:0006914]; calcium-mediated signaling [GO:0019722]; canonical Wnt signaling pathway [GO:0060070]; cellular response to dopamine [GO:1903351]; cellular response to manganese ion [GO:0071287]; cellular response to organic cyclic compound [GO:0071407]; cellular response to oxidative stress [GO:0034599]; cellular response to starvation [GO:0009267]; determination of adult lifespan [GO:0008340]; endocytosis [GO:0006897]; endoplasmic reticulum organization [GO:0007029]; excitatory postsynaptic potential [GO:0060079]; exploration behavior [GO:0035640]; Golgi organization [GO:0007030]; GTP metabolic process [GO:0046039]; intracellular distribution of mitochondria [GO:0048312]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; locomotory exploration behavior [GO:0035641]; lysosome organization [GO:0007040]; MAPK cascade [GO:0000165]; mitochondrion localization [GO:0051646]; mitochondrion organization [GO:0007005]; negative regulation of autophagosome assembly [GO:1902902]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of GTPase activity [GO:0034260]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of late endosome to lysosome transport [GO:1902823]; negative regulation of macroautophagy [GO:0016242]; negative regulation of neuron death [GO:1901215]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein binding [GO:0032091]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein processing [GO:0010955]; negative regulation of protein processing involved in protein targeting to mitochondrion [GO:1903217]; negative regulation of protein targeting to mitochondrion [GO:1903215]; negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation [GO:1903125]; neuromuscular junction development [GO:0007528]; neuron death [GO:0070997]; neuron projection arborization [GO:0140058]; neuron projection morphogenesis [GO:0048812]; olfactory bulb development [GO:0021772]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; phosphorylation [GO:0016310]; positive regulation of autophagy [GO:0010508]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of dopamine receptor signaling pathway [GO:0060161]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of programmed cell death [GO:0043068]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein autoubiquitination [GO:1902499]; positive regulation of protein binding [GO:0032092]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; positive regulation of tumor necrosis factor production [GO:0032760]; protein autophosphorylation [GO:0046777]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein localization to endoplasmic reticulum exit site [GO:0070973]; protein localization to mitochondrion [GO:0070585]; protein phosphorylation [GO:0006468]; reactive oxygen species metabolic process [GO:0072593]; regulation of autophagy [GO:0010506]; regulation of branching morphogenesis of a nerve [GO:2000172]; regulation of CAMKK-AMPK signaling cascade [GO:1905289]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of dopamine receptor signaling pathway [GO:0060159]; regulation of ER to Golgi vesicle-mediated transport [GO:0060628]; regulation of kidney size [GO:0035564]; regulation of locomotion [GO:0040012]; regulation of lysosomal lumen pH [GO:0035751]; regulation of membrane potential [GO:0042391]; regulation of mitochondrial depolarization [GO:0051900]; regulation of mitochondrial fission [GO:0090140]; regulation of neuroblast proliferation [GO:1902692]; regulation of neuron death [GO:1901214]; regulation of neuron maturation [GO:0014041]; regulation of protein kinase A signaling [GO:0010738]; regulation of protein stability [GO:0031647]; regulation of retrograde transport, endosome to Golgi [GO:1905279]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of synaptic vesicle exocytosis [GO:2000300]; regulation of synaptic vesicle transport [GO:1902803]; response to oxidative stress [GO:0006979]; signal transduction [GO:0007165]; spermatogenesis [GO:0007283]; striatum development [GO:0021756]; tangential migration from the subventricular zone to the olfactory bulb [GO:0022028]; Wnt signalosome assembly [GO:1904887] GO:0000139; GO:0000149; GO:0000165; GO:0000287; GO:0001933; GO:0001934; GO:0003779; GO:0003924; GO:0004672; GO:0004674; GO:0004706; GO:0004709; GO:0004722; GO:0005096; GO:0005524; GO:0005525; GO:0005615; GO:0005737; GO:0005739; GO:0005741; GO:0005743; GO:0005759; GO:0005764; GO:0005768; GO:0005783; GO:0005789; GO:0005794; GO:0005798; GO:0005802; GO:0005829; GO:0005886; GO:0005902; GO:0006468; GO:0006606; GO:0006897; GO:0006914; GO:0006979; GO:0007005; GO:0007029; GO:0007030; GO:0007040; GO:0007165; GO:0007254; GO:0007283; GO:0007528; GO:0008017; GO:0008104; GO:0008340; GO:0009267; GO:0010506; GO:0010508; GO:0010738; GO:0010955; GO:0010977; GO:0014041; GO:0015631; GO:0016234; GO:0016242; GO:0016301; GO:0016310; GO:0017075; GO:0018105; GO:0018107; GO:0019722; GO:0021756; GO:0021772; GO:0022028; GO:0030159; GO:0030276; GO:0030424; GO:0030425; GO:0030426; GO:0030672; GO:0031267; GO:0031398; GO:0031410; GO:0031647; GO:0031966; GO:0032091; GO:0032092; GO:0032436; GO:0032473; GO:0032760; GO:0032839; GO:0034211; GO:0034260; GO:0034599; GO:0035556; GO:0035564; GO:0035640; GO:0035641; GO:0035751; GO:0036479; GO:0039706; GO:0040012; GO:0042391; GO:0042802; GO:0042803; GO:0043005; GO:0043025; GO:0043068; GO:0043195; GO:0043204; GO:0043231; GO:0043406; GO:0044325; GO:0044753; GO:0044754; GO:0045121; GO:0045860; GO:0046039; GO:0046777; GO:0048312; GO:0048812; GO:0051018; GO:0051646; GO:0051770; GO:0051900; GO:0051966; GO:0060070; GO:0060079; GO:0060159; GO:0060161; GO:0060628; GO:0060828; GO:0061001; GO:0070062; GO:0070585; GO:0070971; GO:0070973; GO:0070997; GO:0071287; GO:0071407; GO:0072593; GO:0090140; GO:0090263; GO:0090394; GO:0097487; GO:0098794; GO:0098978; GO:0099400; GO:0099523; GO:0106310; GO:0140058; GO:1900244; GO:1901214; GO:1901215; GO:1901727; GO:1902236; GO:1902499; GO:1902692; GO:1902803; GO:1902823; GO:1902902; GO:1903125; GO:1903206; GO:1903215; GO:1903217; GO:1903351; GO:1903980; GO:1904713; GO:1904887; GO:1905279; GO:1905289; GO:1990904; GO:1990909; GO:2000172; GO:2000300 43325 XM_029324971.2 2463 2294 1649 1723 1517 Q8R3S2 1.01e-67 Tetraspanin-33 (Tspan-33) (Penumbra) (mPen) (Proerythroblast new membrane) Mus musculus (Mouse) pore complex assembly [GO:0046931]; protein localization to plasma membrane [GO:0072659]; protein maturation [GO:0051604] GO:0005737; GO:0005886; GO:0005912; GO:0009986; GO:0019899; GO:0046930; GO:0046931; GO:0051604; GO:0072659; GO:0097197 43326 XR_006395330.1 0 0 7 3 2 NA NA NA NA NA NA 43327 XM_044324920.1 0 102 0 0 0 Q9UQ26 3.06e-63 Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2) (Rab-3-interacting protein 3) Homo sapiens (Human) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-ion regulated exocytosis [GO:0017156]; cell differentiation [GO:0030154]; insulin secretion [GO:0030073]; intracellular protein transport [GO:0006886]; positive regulation of dendrite extension [GO:1903861]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of synaptic transmission [GO:0050806]; regulation of exocytosis [GO:0017157]; regulation of membrane potential [GO:0042391]; regulation of synaptic plasticity [GO:0048167]; spontaneous neurotransmitter secretion [GO:0061669] GO:0006886; GO:0007188; GO:0017156; GO:0017157; GO:0030073; GO:0030154; GO:0031267; GO:0042391; GO:0042734; GO:0042995; GO:0044325; GO:0046872; GO:0048167; GO:0048786; GO:0048788; GO:0048791; GO:0050806; GO:0061669; GO:0070062; GO:0097151; GO:1903861; GO:2000463 43328 XM_044324920.1 0 102 0 0 0 Q9UQ26 1.81e-30 Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2) (Rab-3-interacting protein 3) Homo sapiens (Human) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-ion regulated exocytosis [GO:0017156]; cell differentiation [GO:0030154]; insulin secretion [GO:0030073]; intracellular protein transport [GO:0006886]; positive regulation of dendrite extension [GO:1903861]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of synaptic transmission [GO:0050806]; regulation of exocytosis [GO:0017157]; regulation of membrane potential [GO:0042391]; regulation of synaptic plasticity [GO:0048167]; spontaneous neurotransmitter secretion [GO:0061669] GO:0006886; GO:0007188; GO:0017156; GO:0017157; GO:0030073; GO:0030154; GO:0031267; GO:0042391; GO:0042734; GO:0042995; GO:0044325; GO:0046872; GO:0048167; GO:0048786; GO:0048788; GO:0048791; GO:0050806; GO:0061669; GO:0070062; GO:0097151; GO:1903861; GO:2000463 43329 XM_044320488.1 3004 3045 2682 3090 3380 Q9UNA1 5.48e-170 Rho GTPase-activating protein 26 (GTPase regulator associated with focal adhesion kinase) (Oligophrenin-1-like protein) (Rho-type GTPase-activating protein 26) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; nervous system development [GO:0007399]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] GO:0005096; GO:0005543; GO:0005829; GO:0005856; GO:0005925; GO:0007165; GO:0007399; GO:0030036; GO:0051056 43330 XR_006394868.1 68 619 141 782 246 NA NA NA NA NA NA 43331 XM_044311012.1 27 3 17 5 4 NA NA NA NA NA NA 43332 XM_029342225.2 89 29 162 70 212 P18709 7.25e-36 Vitellogenin-A2 (VTG A2) [Cleaved into: Lipovitellin I; Lipovitellin II; Phosvitin] Xenopus laevis (African clawed frog) NA GO:0005319; GO:0045735 43333 XM_029345073.2 452 343 181 486 543 Q758C3 1.1e-29 Protein BTN1 Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii) L-arginine transmembrane transport [GO:1903826]; lysine transport [GO:0015819]; regulation of intracellular pH [GO:0051453] GO:0000324; GO:0005773; GO:0005774; GO:0015819; GO:0051453; GO:1903826 43334 XM_044322483.1 1174 0 55 0 2 NA NA NA NA NA NA 43335 XM_029338794.2 1746 1586 1365 1697 1271 Q08BI9 1.09e-108 Calcium uniporter protein, mitochondrial Danio rerio (Zebrafish) (Brachydanio rerio) actin filament organization [GO:0007015]; calcium import into the mitochondrion [GO:0036444]; calcium-mediated signaling [GO:0019722]; chordate embryonic development [GO:0043009]; convergent extension involved in gastrulation [GO:0060027]; glucose homeostasis [GO:0042593]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrial calcium ion transmembrane transport [GO:0006851]; positive regulation of insulin secretion [GO:0032024]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; protein complex oligomerization [GO:0051259]; regulation of heart contraction [GO:0008016] GO:0005262; GO:0005743; GO:0006851; GO:0007015; GO:0008016; GO:0015292; GO:0019722; GO:0032024; GO:0034704; GO:0036444; GO:0042593; GO:0042802; GO:0043009; GO:0051259; GO:0051560; GO:0051561; GO:0060027; GO:1990246 43336 XR_006391383.1 0 0 8 33 22 NA NA NA NA NA NA 43337 XM_044307312.1 0 34 0 19 4 NA NA NA NA NA NA 43338 XR_006393197.1 1237 2106 302 504 1002 NA NA NA NA NA NA 43339 XM_029353047.2 0 9 0 22 0 Q9CS74 7.28e-143 Protein ecdysoneless homolog Mus musculus (Mouse) fibroblast proliferation [GO:0048144]; mRNA processing [GO:0006397]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; RNA splicing [GO:0008380] GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006397; GO:0008380; GO:0035035; GO:0045944; GO:0048144; GO:2000045 43340 XM_044324051.1 13 0 2 18 15 Q6NYE7 1.16e-34 Transmembrane protein 192 Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005765; GO:0005770 43341 XM_044329092.1 229 284 150 397 402 NA NA NA NA NA NA 43342 XM_029347455.2 1113 1019 753 1242 1155 O93602 1.24e-35 Cyclic AMP-dependent transcription factor ATF-2 (cAMP-dependent transcription factor ATF-2) (Activating transcription factor 2) Gallus gallus (Chicken) cellular response to DNA damage stimulus [GO:0006974]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005741; GO:0006357; GO:0006974; GO:0035497; GO:0046872 43343 XM_029347455.2 1113 1019 753 1242 1155 O93602 3.4e-31 Cyclic AMP-dependent transcription factor ATF-2 (cAMP-dependent transcription factor ATF-2) (Activating transcription factor 2) Gallus gallus (Chicken) cellular response to DNA damage stimulus [GO:0006974]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005741; GO:0006357; GO:0006974; GO:0035497; GO:0046872 43344 XM_044327243.1 5 4 4 3 18 P08953 2.56e-59 Protein toll Drosophila melanogaster (Fruit fly) antifungal innate immune response [GO:0061760]; cell adhesion [GO:0007155]; cell competition in a multicellular organism [GO:0035212]; defense response to Gram-positive bacterium [GO:0050830]; defense response to oomycetes [GO:0002229]; detection of virus [GO:0009597]; dorsal/ventral axis specification [GO:0009950]; heart development [GO:0007507]; innate immune response [GO:0045087]; larval somatic muscle development [GO:0007526]; negative regulation of cell growth [GO:0030308]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of multicellular organism growth [GO:0040015]; positive regulation of antifungal peptide production [GO:0002804]; positive regulation of antimicrobial peptide production [GO:0002225]; positive regulation of hemocyte proliferation [GO:0035208]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of embryonic pattern specification [GO:1902875]; response to tumor cell [GO:0002347]; response to wounding [GO:0009611]; synapse assembly [GO:0007416]; synaptic target inhibition [GO:0016201]; Toll signaling pathway [GO:0008063]; toll-like receptor signaling pathway [GO:0002224] GO:0002224; GO:0002225; GO:0002229; GO:0002347; GO:0002804; GO:0004888; GO:0004896; GO:0005769; GO:0005886; GO:0007155; GO:0007416; GO:0007507; GO:0007526; GO:0008063; GO:0009597; GO:0009611; GO:0009897; GO:0009950; GO:0009986; GO:0016201; GO:0019955; GO:0030308; GO:0032154; GO:0035208; GO:0035212; GO:0038023; GO:0040015; GO:0042802; GO:0045087; GO:0045944; GO:0046627; GO:0046790; GO:0050135; GO:0050830; GO:0061760; GO:0061809; GO:0070976; GO:1902875 43345 XM_029330492.2 2678 2213 2270 3334 3057 Q6P3Q6 2.22e-168 Ceramide transfer protein (CERT) (Collagen type IV alpha-3-binding protein) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) lipid transport [GO:0006869] GO:0005783; GO:0005794; GO:0006869; GO:0008289 43346 XM_029323446.2 533 494 266 381 441 NA NA NA NA NA NA 43347 XM_044309071.1 0 0 0 8 0 Q4R9C4 2.97e-46 G2/M phase-specific E3 ubiquitin-protein ligase (EC 2.3.2.26) (G2/M phase-specific HECT-type E3 ubiquitin transferase) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) apoptotic process [GO:0006915] GO:0004842; GO:0005730; GO:0005737; GO:0006915; GO:0046872 43348 XM_029344917.2 98 35 52 171 181 NA NA NA NA NA NA 43349 XM_044317560.1 0 0 0 0 6 NA NA NA NA NA NA 43350 XM_029333164.2 982 664 822 1433 1221 Q96N96 3.92e-140 Spermatogenesis-associated protein 13 (APC-stimulated guanine nucleotide exchange factor 2) (Asef2) Homo sapiens (Human) cell migration [GO:0016477]; filopodium assembly [GO:0046847]; lamellipodium assembly [GO:0030032]; regulation of cell migration [GO:0030334]; regulation of small GTPase mediated signal transduction [GO:0051056] GO:0005085; GO:0005654; GO:0005737; GO:0005829; GO:0016477; GO:0030027; GO:0030032; GO:0030175; GO:0030334; GO:0032587; GO:0042802; GO:0046847; GO:0051056 43351 XM_044318874.1 0 0 10 0 0 A1A600 4.98e-40 EF-hand calcium-binding domain-containing protein 4A (Calcium release-activated channel regulator 2B) Danio rerio (Zebrafish) (Brachydanio rerio) store-operated calcium entry [GO:0002115] GO:0002115; GO:0005509; GO:0005737 43352 XM_029341711.2 82 48 25 73 134 P49321 3.37e-32 Nuclear autoantigenic sperm protein (NASP) Homo sapiens (Human) blastocyst development [GO:0001824]; cell cycle [GO:0007049]; CENP-A containing chromatin assembly [GO:0034080]; DNA replication [GO:0006260]; DNA replication-dependent chromatin assembly [GO:0006335]; male gonad development [GO:0008584]; nucleosome assembly [GO:0006334]; protein transport [GO:0015031]; response to testosterone [GO:0033574] GO:0000785; GO:0001824; GO:0005634; GO:0005654; GO:0005737; GO:0006260; GO:0006334; GO:0006335; GO:0007049; GO:0008584; GO:0015031; GO:0032991; GO:0033574; GO:0034080; GO:0042393; GO:0044877 43353 XM_044314126.1 98 38 38 71 42 NA NA NA NA NA NA 43354 XM_044325734.1 610 563 334 851 971 Q4A3R3 4.6e-35 Deleted in malignant brain tumors 1 protein (Hensin) Sus scrofa (Pig) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031]; zymogen activation [GO:0031638] GO:0004252; GO:0005044; GO:0005576; GO:0005886; GO:0015031; GO:0019898; GO:0030154; GO:0030658; GO:0031638; GO:0035375; GO:0042589; GO:0050829; GO:0050830 43355 XM_044325734.1 610 563 334 851 971 Q4A3R3 3.62e-29 Deleted in malignant brain tumors 1 protein (Hensin) Sus scrofa (Pig) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031]; zymogen activation [GO:0031638] GO:0004252; GO:0005044; GO:0005576; GO:0005886; GO:0015031; GO:0019898; GO:0030154; GO:0030658; GO:0031638; GO:0035375; GO:0042589; GO:0050829; GO:0050830 43356 XM_044325734.1 610 563 334 851 971 Q4A3R3 8.44e-27 Deleted in malignant brain tumors 1 protein (Hensin) Sus scrofa (Pig) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031]; zymogen activation [GO:0031638] GO:0004252; GO:0005044; GO:0005576; GO:0005886; GO:0015031; GO:0019898; GO:0030154; GO:0030658; GO:0031638; GO:0035375; GO:0042589; GO:0050829; GO:0050830 43357 XM_044325734.1 610 563 334 851 971 Q4A3R3 9.58e-27 Deleted in malignant brain tumors 1 protein (Hensin) Sus scrofa (Pig) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031]; zymogen activation [GO:0031638] GO:0004252; GO:0005044; GO:0005576; GO:0005886; GO:0015031; GO:0019898; GO:0030154; GO:0030658; GO:0031638; GO:0035375; GO:0042589; GO:0050829; GO:0050830 43358 XM_044325734.1 610 563 334 851 971 Q4A3R3 3.51e-26 Deleted in malignant brain tumors 1 protein (Hensin) Sus scrofa (Pig) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031]; zymogen activation [GO:0031638] GO:0004252; GO:0005044; GO:0005576; GO:0005886; GO:0015031; GO:0019898; GO:0030154; GO:0030658; GO:0031638; GO:0035375; GO:0042589; GO:0050829; GO:0050830 43359 XM_044325734.1 610 563 334 851 971 Q4A3R3 1.68e-24 Deleted in malignant brain tumors 1 protein (Hensin) Sus scrofa (Pig) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031]; zymogen activation [GO:0031638] GO:0004252; GO:0005044; GO:0005576; GO:0005886; GO:0015031; GO:0019898; GO:0030154; GO:0030658; GO:0031638; GO:0035375; GO:0042589; GO:0050829; GO:0050830 43360 XM_044325734.1 610 563 334 851 971 Q4A3R3 3.02e-24 Deleted in malignant brain tumors 1 protein (Hensin) Sus scrofa (Pig) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031]; zymogen activation [GO:0031638] GO:0004252; GO:0005044; GO:0005576; GO:0005886; GO:0015031; GO:0019898; GO:0030154; GO:0030658; GO:0031638; GO:0035375; GO:0042589; GO:0050829; GO:0050830 43361 XM_044325734.1 610 563 334 851 971 Q4A3R3 3.02e-24 Deleted in malignant brain tumors 1 protein (Hensin) Sus scrofa (Pig) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031]; zymogen activation [GO:0031638] GO:0004252; GO:0005044; GO:0005576; GO:0005886; GO:0015031; GO:0019898; GO:0030154; GO:0030658; GO:0031638; GO:0035375; GO:0042589; GO:0050829; GO:0050830 43362 XR_006394503.1 2 0 32 32 33 NA NA NA NA NA NA 43363 XM_044316889.1 518 253 143 0 203 Q9GLK0 1.66e-170 Protein-glutamine gamma-glutamyltransferase K (EC 2.3.2.13) (Epidermal TGase) (Transglutaminase K) (TG(K)) (TGK) (TGase K) (Transglutaminase-1) (TGase-1) Canis lupus familiaris (Dog) (Canis familiaris) keratinization [GO:0031424]; peptide cross-linking [GO:0018149]; positive regulation of cell cycle [GO:0045787]; positive regulation of keratinocyte proliferation [GO:0010838] GO:0003810; GO:0010838; GO:0016020; GO:0018149; GO:0031424; GO:0045787; GO:0046872 43364 XM_029345735.2 30 4 30 23 43 NA NA NA NA NA NA 43365 XM_029334903.2 1679 1597 1151 1750 2101 Q6P1V4 0 Eukaryotic translation initiation factor 3 subunit C (eIF3c) (Eukaryotic translation initiation factor 3 subunit 8) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) formation of cytoplasmic translation initiation complex [GO:0001732]; translational initiation [GO:0006413] GO:0001732; GO:0003723; GO:0003743; GO:0005852; GO:0006413; GO:0016282; GO:0031369; GO:0033290 43366 XM_029334903.2 1679 1597 1151 1750 2101 Q6P1V4 1.22e-39 Eukaryotic translation initiation factor 3 subunit C (eIF3c) (Eukaryotic translation initiation factor 3 subunit 8) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) formation of cytoplasmic translation initiation complex [GO:0001732]; translational initiation [GO:0006413] GO:0001732; GO:0003723; GO:0003743; GO:0005852; GO:0006413; GO:0016282; GO:0031369; GO:0033290 43367 XM_044315792.1 139 171 3 212 1 NA NA NA NA NA NA 43368 XM_044311464.1 138 101 234 1 227 D3ZS74 1.5e-33 Metalloendopeptidase OMA1, mitochondrial (EC 3.4.24.-) (Overlapping with the m-AAA protease 1 homolog) Rattus norvegicus (Rat) cristae formation [GO:0042407]; diet induced thermogenesis [GO:0002024]; energy homeostasis [GO:0097009]; glucose metabolic process [GO:0006006]; HRI-mediated signaling [GO:0140468]; integrated stress response signaling [GO:0140467]; lipid metabolic process [GO:0006629]; mitochondrial protein processing [GO:0034982]; mitochondrial respiratory chain complex assembly [GO:0033108]; mitochondrion organization [GO:0007005]; negative regulation of mitochondrial fusion [GO:0010637]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cold-induced thermogenesis [GO:0120162]; protein autoprocessing [GO:0016540]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of cristae formation [GO:1903850]; zymogen activation [GO:0031638] GO:0002024; GO:0004222; GO:0005739; GO:0005743; GO:0006006; GO:0006515; GO:0006629; GO:0007005; GO:0008289; GO:0010637; GO:0016020; GO:0016540; GO:0031638; GO:0031966; GO:0033108; GO:0034982; GO:0042407; GO:0043065; GO:0046872; GO:0051603; GO:0097009; GO:0120162; GO:0140467; GO:0140468; GO:1903850 43369 XM_044317296.1 4 1 0 0 7 NA NA NA NA NA NA 43370 XM_029338693.2 412 535 62 747 779 NA NA NA NA NA NA 43371 XM_029334468.2 142 400 192 170 57 Q6DKN2 9.36e-32 Homeobox protein OTX2-B (xOTX2-B) (Orthodenticle 2-B) (Orthodenticle-A-like protein B) Xenopus laevis (African clawed frog) NA GO:0000981; GO:0003677; GO:0005634 43372 XM_029338239.2 110 121 57 5 63 NA NA NA NA NA NA 43373 XM_029345057.2 0 0 0 9 34 NA NA NA NA NA NA 43374 XM_044307298.1 42 33 54 42 100 Q9D5U8 4.99e-43 Cyclic nucleotide-binding domain-containing protein 2 (Cyclic nucleotide receptor involved in sperm function) Mus musculus (Mouse) spermatogenesis [GO:0007283] GO:0005829; GO:0007283; GO:0030552 43375 XM_044309226.1 11 7 44 202 11 NA NA NA NA NA NA 43376 XM_044327966.1 76 52 34 58 50 Q8BZB2 9.4e-68 Phosphopantothenoylcysteine decarboxylase (PPC-DC) (EC 4.1.1.36) (CoaC) Mus musculus (Mouse) coenzyme A biosynthetic process [GO:0015937] GO:0004633; GO:0010181; GO:0015937; GO:0042802; GO:0071513 43377 XM_029334127.2 0 6 3 5 2 Q09225 1.73e-63 Nose resistant to fluoxetine protein 6 (Protein nrf-6) Caenorhabditis elegans lipid transport [GO:0006869] GO:0006869; GO:0008289; GO:0016020; GO:0016747 43378 XM_029341354.2 641 469 350 1042 508 A7SGF0 4.37e-66 BLOC-1-related complex subunit 8 homolog Nematostella vectensis (Starlet sea anemone) NA GO:0005765; GO:0099078 43379 XM_029351492.2 0 15 32 0 14 NA NA NA NA NA NA 43380 XM_029327241.2 24 21 0 26 14 NA NA NA NA NA NA 43381 XM_029357035.2 4229 2814 1899 3102 3324 Q5F471 0 Serine/threonine-protein phosphatase 6 regulatory subunit 3 (SAPS domain family member 3) Gallus gallus (Chicken) regulation of phosphoprotein phosphatase activity [GO:0043666] GO:0005634; GO:0005829; GO:0019888; GO:0019903; GO:0043666 43382 XM_029349191.2 10 1504 1096 879 10 P05426 7.52e-107 60S ribosomal protein L7 Rattus norvegicus (Rat) liver regeneration [GO:0097421]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; ribosomal large subunit biogenesis [GO:0042273]; rRNA processing [GO:0006364] GO:0000463; GO:0003677; GO:0003723; GO:0003729; GO:0003735; GO:0005840; GO:0005844; GO:0006364; GO:0008097; GO:0014069; GO:0022625; GO:0022626; GO:0031672; GO:0042273; GO:0042802; GO:0045202; GO:0097421; GO:1990904 43383 XR_006397255.1 10 94 0 14 12 NA NA NA NA NA NA 43384 XM_044307237.1 37 26 11 35 31 NA NA NA NA NA NA 43385 XM_029334852.2 110 68 98 61 139 NA NA NA NA NA NA 43386 XM_044318142.1 633 376 490 738 647 O46382 0 Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (ADP-ribosylation factor guanine nucleotide-exchange factor 1) (p200 ARF guanine nucleotide exchange factor) (p200 ARF-GEP1) Bos taurus (Bovine) endomembrane system organization [GO:0010256]; Golgi organization [GO:0007030]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of GTPase activity [GO:0034260]; positive regulation of wound healing [GO:0090303]; protein glycosylation [GO:0006486]; protein transport [GO:0015031]; regulation of ARF protein signal transduction [GO:0032012]; regulation of establishment of cell polarity [GO:2000114] GO:0000139; GO:0005085; GO:0005730; GO:0005802; GO:0005829; GO:0006486; GO:0007030; GO:0010256; GO:0015031; GO:0016363; GO:0030532; GO:0030837; GO:0032012; GO:0034237; GO:0034260; GO:0048471; GO:0090303; GO:2000114 43387 XM_044321865.1 169 29 54 43 46 D8VNS8 8.24e-62 Ryncolin-2 Cerberus rynchops (Dog-faced water snake) NA GO:0005576; GO:0090729 43388 XM_044311794.1 61 1 8 13 10 NA NA NA NA NA NA 43389 XM_044311225.1 10 28 14 3 36 P46023 2.08e-92 G-protein coupled receptor GRL101 Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004930; GO:0005886 43390 XM_044325385.1 2176 1152 992 1124 1342 P63329 0 Protein phosphatase 3 catalytic subunit alpha (EC 3.1.3.16) (CAM-PRP catalytic subunit) (Calcineurin A alpha) (Calmodulin-dependent calcineurin A subunit alpha isoform) (CNA alpha) (Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform) Rattus norvegicus (Rat) aging [GO:0007568]; brain development [GO:0007420]; calcineurin-mediated signaling [GO:0097720]; calcineurin-NFAT signaling cascade [GO:0033173]; calcium ion transport [GO:0006816]; calcium-mediated signaling [GO:0019722]; cardiac muscle hypertrophy in response to stress [GO:0014898]; cellular response to glucose stimulus [GO:0071333]; dendrite morphogenesis [GO:0048813]; dephosphorylation [GO:0016311]; epidermis development [GO:0008544]; excitatory postsynaptic potential [GO:0060079]; G1/S transition of mitotic cell cycle [GO:0000082]; keratinocyte differentiation [GO:0030216]; modulation of chemical synaptic transmission [GO:0050804]; multicellular organismal response to stress [GO:0033555]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of chromatin binding [GO:0035562]; negative regulation of dendrite morphogenesis [GO:0050774]; negative regulation of gene expression [GO:0010629]; negative regulation of insulin secretion [GO:0046676]; negative regulation of miRNA maturation [GO:1903799]; negative regulation of signaling [GO:0023057]; peptidyl-serine dephosphorylation [GO:0070262]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cardiac muscle hypertrophy in response to stress [GO:1903244]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of connective tissue replacement [GO:1905205]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endocytosis [GO:0045807]; positive regulation of gene expression [GO:0010628]; positive regulation of glomerulus development [GO:0090193]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of saliva secretion [GO:0046878]; positive regulation of transcription by RNA polymerase II [GO:0045944]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; protein dephosphorylation [GO:0006470]; protein import into nucleus [GO:0006606]; regulation of cell proliferation involved in kidney morphogenesis [GO:0061006]; renal filtration [GO:0097205]; response to amphetamine [GO:0001975]; response to calcium ion [GO:0051592]; skeletal muscle fiber development [GO:0048741]; transition between fast and slow fiber [GO:0014883] GO:0000082; GO:0001975; GO:0004721; GO:0004722; GO:0004723; GO:0005516; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005829; GO:0005886; GO:0005955; GO:0006470; GO:0006606; GO:0006816; GO:0007420; GO:0007568; GO:0008544; GO:0009898; GO:0010613; GO:0010628; GO:0010629; GO:0014883; GO:0014898; GO:0016018; GO:0016311; GO:0017018; GO:0019722; GO:0019899; GO:0023057; GO:0030018; GO:0030216; GO:0030335; GO:0033173; GO:0033192; GO:0033555; GO:0035562; GO:0042104; GO:0042383; GO:0043197; GO:0044877; GO:0045202; GO:0045669; GO:0045672; GO:0045785; GO:0045807; GO:0045944; GO:0045955; GO:0046676; GO:0046872; GO:0046878; GO:0046983; GO:0048741; GO:0048813; GO:0050774; GO:0050804; GO:0051091; GO:0051117; GO:0051592; GO:0060079; GO:0061006; GO:0070262; GO:0071333; GO:0090193; GO:0097205; GO:0097720; GO:0098685; GO:0098794; GO:0098978; GO:0099170; GO:0140677; GO:1903244; GO:1903799; GO:1905205 43391 XM_029352563.2 1792 2769 650 1447 1390 P80193 4.55e-51 Gamma-butyrobetaine dioxygenase (EC 1.14.11.1) (Gamma-butyrobetaine hydroxylase) (Gamma-BBH) (Gamma-butyrobetaine,2-oxoglutarate dioxygenase) Pseudomonas sp. (strain AK-1) carnitine biosynthetic process [GO:0045329] GO:0005506; GO:0005737; GO:0008336; GO:0045329 43392 XM_029340128.2 113 69 76 681 622 Q9WUJ8 9.24e-38 Origin recognition complex subunit 6 Mus musculus (Mouse) DNA replication initiation [GO:0006270]; DNA-templated DNA replication [GO:0006261]; negative regulation of cell division [GO:0051782] GO:0000808; GO:0001650; GO:0003677; GO:0005654; GO:0005664; GO:0006261; GO:0006270; GO:0051782 43393 XM_044312126.1 0 1 28 8 41 O60290 6.09e-54 Zinc finger protein 862 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006355; GO:0046872; GO:0046983 43394 XM_044322503.1 446 127 82 301 152 Q9NXS3 5.47e-51 Kelch-like protein 28 (BTB/POZ domain-containing protein 5) Homo sapiens (Human) NA NA 43395 XM_029336731.2 27 9 37 28 21 Q61292 4.63e-117 Laminin subunit beta-2 (Laminin-11 subunit beta) (Laminin-14 subunit beta) (Laminin-15 subunit beta) (Laminin-3 subunit beta) (Laminin-4 subunit beta) (Laminin-7 subunit beta) (Laminin-9 subunit beta) (S-laminin subunit beta) (S-LAM beta) Mus musculus (Mouse) animal organ morphogenesis [GO:0009887]; astrocyte development [GO:0014002]; axon extension involved in regeneration [GO:0048677]; axon guidance [GO:0007411]; basement membrane assembly [GO:0070831]; cell migration [GO:0016477]; cell morphogenesis involved in differentiation [GO:0000904]; metanephric glomerular basement membrane development [GO:0072274]; metanephric podocyte development [GO:0072249]; neuromuscular junction development [GO:0007528]; neuron projection development [GO:0031175]; positive regulation of cell adhesion [GO:0045785]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of muscle cell differentiation [GO:0051149]; regulation of basement membrane organization [GO:0110011]; retina development in camera-type eye [GO:0060041]; Schwann cell development [GO:0014044]; substrate adhesion-dependent cell spreading [GO:0034446]; synapse organization [GO:0050808]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0000904; GO:0005178; GO:0005201; GO:0005576; GO:0005604; GO:0005608; GO:0007411; GO:0007528; GO:0007601; GO:0009887; GO:0009888; GO:0014002; GO:0014044; GO:0016477; GO:0031175; GO:0031594; GO:0034446; GO:0043083; GO:0043256; GO:0045202; GO:0045785; GO:0048677; GO:0050808; GO:0051149; GO:0060041; GO:0062023; GO:0070831; GO:0072249; GO:0072274; GO:0098637; GO:0110011; GO:0150043; GO:2001046 43396 XM_044314635.1 14 7 20 19 18 NA NA NA NA NA NA 43397 XM_044319844.1 1881 2161 1589 2232 2209 NA NA NA NA NA NA 43398 XM_044320699.1 0 0 2 11 8 NA NA NA NA NA NA 43399 XM_044316032.1 7 48 7 47 0 NA NA NA NA NA NA 43400 XM_044321728.1 16 0 2 7 0 NA NA NA NA NA NA 43401 XM_029357858.2 45 4 14 15 33 NA NA NA NA NA NA 43402 XM_029326619.2 0 0 0 48 0 Q9W735 4.39e-39 Prominin-1-A (Prominin-like protein 1) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005783; GO:0005793; GO:0005886; GO:0005902; GO:0005929; GO:0009986; GO:0015485; GO:0016324; GO:0031528; GO:0071914 43403 XM_044328383.1 0 7 0 0 8 NA NA NA NA NA NA 43404 XM_029346657.2 69 48 43 16 72 Q8VCK5 3.76e-91 Kelch-like protein 20 (Kelch-like ECT2-interacting protein) Mus musculus (Mouse) Golgi to endosome transport [GO:0006895]; negative regulation of apoptotic process [GO:0043066]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K33-linked ubiquitination [GO:1990390]; protein transport [GO:0015031]; protein ubiquitination [GO:0016567] GO:0003779; GO:0004842; GO:0005737; GO:0005794; GO:0005802; GO:0005829; GO:0006895; GO:0015031; GO:0016567; GO:0016605; GO:0019964; GO:0030424; GO:0030425; GO:0031463; GO:0043066; GO:0043161; GO:0048471; GO:1990390 43405 XM_029325078.2 303 264 122 366 311 NA NA NA NA NA NA 43406 XM_044320753.1 36 1 4 0 1 NA NA NA NA NA NA 43407 XM_029327220.2 388 103 158 340 314 P47736 3.67e-113 Rap1 GTPase-activating protein 1 (Rap1GAP) (Rap1GAP1) Homo sapiens (Human) activation of GTPase activity [GO:0090630]; adaptive immune response [GO:0002250]; cellular response to glial cell derived neurotrophic factor [GO:1990792]; negative regulation of GTP binding [GO:1904425]; negative regulation of microvillus assembly [GO:1903697]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of thyroid gland epithelial cell proliferation [GO:1904442]; positive regulation of GTPase activity [GO:0043547]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] GO:0000139; GO:0002250; GO:0003924; GO:0005096; GO:0005737; GO:0005769; GO:0005829; GO:0007165; GO:0016020; GO:0030424; GO:0030425; GO:0031267; GO:0042803; GO:0043025; GO:0043087; GO:0043547; GO:0045665; GO:0051056; GO:0090630; GO:1903697; GO:1904425; GO:1904442; GO:1990792 43408 XM_029342369.2 246 40 150 75 287 Q8N3J2 7.81e-50 N(6)-adenine-specific methyltransferase METTL4 (Methyltransferase-like protein 4) (N(6)-adenine-specific DNA methyltransferase METTL4) (EC 2.1.1.72) (snRNA (2'-O-methyladenosine-N(6)-)-methyltransferase METTL4) (EC 2.1.1.-) Homo sapiens (Human) chromatin organization [GO:0006325]; DNA methylation on adenine [GO:0032775]; regulation of chromatin organization [GO:1902275]; regulation of mitochondrial DNA replication [GO:0090296]; regulation of mitochondrial transcription [GO:1903108]; regulation of RNA splicing [GO:0043484]; snRNA (adenine-N6)-methylation [GO:0120049] GO:0003676; GO:0005634; GO:0005759; GO:0005829; GO:0006325; GO:0008168; GO:0008173; GO:0009007; GO:0032775; GO:0043484; GO:0090296; GO:0106347; GO:0120049; GO:1902275; GO:1903108 43409 XM_044308490.1 457 154 29 90 101 P42285 5.72e-135 Exosome RNA helicase MTR4 (EC 3.6.4.13) (ATP-dependent RNA helicase DOB1) (ATP-dependent RNA helicase SKIV2L2) (Superkiller viralicidic activity 2-like 2) (TRAMP-like complex helicase) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; maturation of 5.8S rRNA [GO:0000460]; mRNA splicing, via spliceosome [GO:0000398]; RNA catabolic process [GO:0006401]; rRNA processing [GO:0006364]; snRNA catabolic process [GO:0016076] GO:0000398; GO:0000460; GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0006364; GO:0006401; GO:0006974; GO:0016076; GO:0016607; GO:0016887; GO:0031499; GO:0071013 43410 XM_029341487.2 175 151 143 259 252 Q9EPK6 1.29e-76 Nucleotide exchange factor SIL1 Mus musculus (Mouse) protein transport [GO:0015031] GO:0000774; GO:0005783; GO:0005788; GO:0015031; GO:0042802 43411 XM_044308557.1 63 14 71 103 125 NA NA NA NA NA NA 43412 XM_044313758.1 126 116 111 100 131 O17185 5.73e-36 Two pore potassium channel protein sup-9 (Suppressor of unc-93 protein 9) (n2P38) Caenorhabditis elegans potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of muscle contraction [GO:0006937]; stabilization of membrane potential [GO:0030322] GO:0005267; GO:0005886; GO:0006813; GO:0006937; GO:0015271; GO:0022841; GO:0030322; GO:0036195; GO:0055120; GO:0071805 43413 XM_044313758.1 126 116 111 100 131 O17185 2.61e-24 Two pore potassium channel protein sup-9 (Suppressor of unc-93 protein 9) (n2P38) Caenorhabditis elegans potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of muscle contraction [GO:0006937]; stabilization of membrane potential [GO:0030322] GO:0005267; GO:0005886; GO:0006813; GO:0006937; GO:0015271; GO:0022841; GO:0030322; GO:0036195; GO:0055120; GO:0071805 43414 XM_029342860.2 10 4 18 1 29 NA NA NA NA NA NA 43415 XR_006394815.1 11 0 14 5 39 NA NA NA NA NA NA 43416 XM_044324485.1 2 17 0 0 18 Q96AY4 5.82e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 43417 XM_044315330.1 171 96 28 65 59 NA NA NA NA NA NA 43418 XM_044323516.1 16 16 17 27 85 NA NA NA NA NA NA 43419 XM_029342187.2 1059 878 489 775 888 Q6GPB6 3.87e-114 E3 ubiquitin-protein ligase KCMF1 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase KCMF1) Xenopus laevis (African clawed frog) macromolecule metabolic process [GO:0043170]; nitrogen compound metabolic process [GO:0006807]; primary metabolic process [GO:0044238] GO:0006807; GO:0008270; GO:0016740; GO:0043170; GO:0044238 43420 XM_044310905.1 167 233 171 120 59 Q7RTR2 1.96e-39 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 43421 XM_044310905.1 167 233 171 120 59 Q7RTR2 5.48e-39 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 43422 XM_044310905.1 167 233 171 120 59 Q7RTR2 6.71e-38 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 43423 XM_044310905.1 167 233 171 120 59 Q7RTR2 1.28e-36 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 43424 XM_044310905.1 167 233 171 120 59 Q7RTR2 7.82e-25 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 43425 XM_044309722.1 0 0 0 0 10 NA NA NA NA NA NA 43426 XM_029337104.2 0 0 0 64 220 Q8TCT0 5.43e-75 Ceramide kinase (hCERK) (EC 2.7.1.138) (Acylsphingosine kinase) (Lipid kinase 4) (LK4) Homo sapiens (Human) ceramide metabolic process [GO:0006672]; glycosphingolipid metabolic process [GO:0006687]; phosphorylation [GO:0016310]; sphingolipid metabolic process [GO:0006665] GO:0000287; GO:0001727; GO:0001729; GO:0005524; GO:0005737; GO:0005886; GO:0006665; GO:0006672; GO:0006687; GO:0016020; GO:0016310; GO:0102773 43427 XM_044319345.1 790 551 340 498 484 Q8C0J6 8.38e-26 Ankyrin repeat domain-containing protein SOWAHC (Ankyrin repeat domain-containing protein 57) (Protein sosondowah homolog C) Mus musculus (Mouse) NA NA 43428 XM_044325849.1 10 9 3 17 14 NA NA NA NA NA NA 43429 XM_044318835.1 493 302 5 227 1287 Q61107 3.54e-44 Guanylate-binding protein 4 (EC 3.6.5.-) (GTP-binding protein 3) (GBP-3) (GTP-binding protein 4) (GBP-4) (Guanine nucleotide-binding protein 4) (Guanylate-binding protein 3) Mus musculus (Mouse) adhesion of symbiont to host [GO:0044406]; cellular response to interferon-beta [GO:0035458]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to type II interferon [GO:0071346]; defense response to Gram-positive bacterium [GO:0050830]; defense response to protozoan [GO:0042832] GO:0000139; GO:0003924; GO:0005525; GO:0005634; GO:0005794; GO:0005829; GO:0005886; GO:0020005; GO:0031410; GO:0035458; GO:0042802; GO:0042803; GO:0042832; GO:0044406; GO:0048471; GO:0050830; GO:0071346; GO:0071356 43430 XM_029337559.2 0 10 0 0 0 NA NA NA NA NA NA 43431 XM_044308595.1 4 4 16 7 24 NA NA NA NA NA NA 43432 XM_044320245.1 7 1 13 5 180 P81139 4.6e-56 Pancreatic lipase-related protein 2 (PL-RP2) (Cytotoxic T lymphocyte lipase) (GPL) (Galactolipase) (EC 3.1.1.26) (Triacylglycerol lipase) (EC 3.1.1.3) Cavia porcellus (Guinea pig) galactolipid catabolic process [GO:0019376]; lipid metabolic process [GO:0006629]; phospholipid catabolic process [GO:0009395]; phospholipid metabolic process [GO:0006644]; triglyceride catabolic process [GO:0019433] GO:0004620; GO:0004806; GO:0005509; GO:0005615; GO:0006629; GO:0006644; GO:0009395; GO:0016020; GO:0019376; GO:0019433; GO:0031410; GO:0043005; GO:0047372; GO:0047714; GO:0102549 43433 XM_029356303.2 11174 6599 3486 8617 917 L5KLU7 1.29e-46 NA NA NA NA 43434 XM_044307080.1 2226 636 1063 1130 1136 Q9BUD6 4.68e-30 Spondin-2 (Differentially expressed in cancerous and non-cancerous lung cells 1) (DIL-1) (Mindin) Homo sapiens (Human) cell adhesion [GO:0007155]; cellular response to lipopolysaccharide [GO:0071222]; defense response to fungus [GO:0050832]; defense response to virus [GO:0051607]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; mast cell mediated immunity [GO:0002448]; opsonization [GO:0008228]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of tumor necrosis factor production [GO:0032760] GO:0001530; GO:0002448; GO:0003823; GO:0007155; GO:0008228; GO:0031012; GO:0032755; GO:0032760; GO:0043152; GO:0045087; GO:0046872; GO:0050832; GO:0051607; GO:0060907; GO:0070062; GO:0071222 43435 XM_044307080.1 2226 636 1063 1130 1136 Q9BUD6 3.69e-22 Spondin-2 (Differentially expressed in cancerous and non-cancerous lung cells 1) (DIL-1) (Mindin) Homo sapiens (Human) cell adhesion [GO:0007155]; cellular response to lipopolysaccharide [GO:0071222]; defense response to fungus [GO:0050832]; defense response to virus [GO:0051607]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; mast cell mediated immunity [GO:0002448]; opsonization [GO:0008228]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of tumor necrosis factor production [GO:0032760] GO:0001530; GO:0002448; GO:0003823; GO:0007155; GO:0008228; GO:0031012; GO:0032755; GO:0032760; GO:0043152; GO:0045087; GO:0046872; GO:0050832; GO:0051607; GO:0060907; GO:0070062; GO:0071222 43436 XM_044315634.1 17 16 23 36 48 NA NA NA NA NA NA 43437 XM_044323966.1 0 60 0 41 58 NA NA NA NA NA NA 43438 XM_044327967.1 33 29 44 60 71 Q96CD2 4.68e-42 Phosphopantothenoylcysteine decarboxylase (PPC-DC) (EC 4.1.1.36) (CoaC) Homo sapiens (Human) coenzyme A biosynthetic process [GO:0015937] GO:0004633; GO:0005829; GO:0010181; GO:0015937; GO:0042802; GO:0071513 43439 XR_006396451.1 7 4 48 19 31 NA NA NA NA NA NA 43440 XM_044323462.1 0 0 19 0 51 NA NA NA NA NA NA 43441 XM_029327723.2 1363 1322 868 1911 2110 Q9UI14 4.42e-31 Prenylated Rab acceptor protein 1 (PRA1 family protein 1) Homo sapiens (Human) NA GO:0005794; GO:0005886; GO:0008021; GO:0008022; GO:0016020; GO:0042802; GO:0070064 43442 XM_044322624.1 2 8 1 1 966 NA NA NA NA NA NA 43443 XM_044309405.1 26 0 15 0 127 NA NA NA NA NA NA 43444 XM_044312314.1 103 48 7 55 9 NA NA NA NA NA NA 43445 XM_029343937.2 2968 2637 1013 1970 467 NA NA NA NA NA NA 43446 XM_029349012.2 0 32 0 4 12 P58307 4.5e-31 Orexin/Hypocretin receptor type 1 (Hypocretin receptor type 1) (Orexin receptor type 1) (Ox-1-R) (Ox1-R) (Ox1R) Mus musculus (Mouse) feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0004930; GO:0005886; GO:0007186; GO:0007218; GO:0007631; GO:0016499; GO:0017046; GO:0051480; GO:0070374 43447 XR_003824850.2 13 7 5 1 18 NA NA NA NA NA NA 43448 XR_006395838.1 19 93 162 130 21 NA NA NA NA NA NA 43449 XM_044322846.1 173 0 51 18 0 Q9N0E7 0 Molybdenum cofactor sulfurase (MCS) (MOS) (MoCo sulfurase) (EC 2.8.1.9) (Molybdenum cofactor sulfurtransferase) Bos taurus (Bovine) Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdopterin cofactor metabolic process [GO:0043545] GO:0006777; GO:0008265; GO:0016829; GO:0030151; GO:0030170; GO:0043545; GO:0102867 43450 XM_044313491.1 503 182 313 69 67 P48733 2.84e-50 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Bos taurus (Bovine) antibacterial innate immune response [GO:0140367]; defense response to Gram-negative bacterium [GO:0050829] GO:0000922; GO:0005201; GO:0005509; GO:0005576; GO:0005929; GO:0016020; GO:0016323; GO:0016324; GO:0031012; GO:0050829; GO:0060170; GO:0140367 43451 XM_029346709.2 2060 1480 759 1634 1956 P27041 5.32e-131 Activin receptor type-2B (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB) Xenopus laevis (African clawed frog) protein phosphorylation [GO:0006468] GO:0004675; GO:0005524; GO:0006468; GO:0016020 43452 XR_006392872.1 41 2 25 5 151 NA NA NA NA NA NA 43453 XM_044307420.1 20 22 0 20 7 NA NA NA NA NA NA 43454 XM_029358043.2 52 0 0 0 45 Q5M888 1.2e-88 UPF0415 protein C7orf25 homolog Rattus norvegicus (Rat) NA NA 43455 XM_029341891.2 543 417 280 889 836 P35224 0 Catenin beta (Beta-catenin) Urechis caupo (Innkeeper worm) (Spoonworm) cell adhesion [GO:0007155] GO:0005737; GO:0005856; GO:0007155; GO:0045296 43456 XM_029346994.2 19 7 0 0 19 A1L1W9 1.2e-38 Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10) Danio rerio (Zebrafish) (Brachydanio rerio) aromatic amino acid transport [GO:0015801]; thyroid hormone transport [GO:0070327] GO:0005302; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0070327 43457 XM_044313687.1 3 4 7 14 36 NA NA NA NA NA NA 43458 XM_044320849.1 295 300 124 166 130 NA NA NA NA NA NA 43459 XM_044317433.1 4957 4293 4032 6105 6156 P11883 1.35e-168 Aldehyde dehydrogenase, dimeric NADP-preferring (EC 1.2.1.5) (Aldehyde dehydrogenase family 3 member A1) (HTC-ALDH) (Tumor-associated aldehyde dehydrogenase) Rattus norvegicus (Rat) aging [GO:0007568]; cellular aldehyde metabolic process [GO:0006081]; lipid metabolic process [GO:0006629]; positive regulation of cell population proliferation [GO:0008284]; response to cAMP [GO:0051591]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]; response to xenobiotic stimulus [GO:0009410] GO:0001666; GO:0004028; GO:0004029; GO:0005737; GO:0005829; GO:0006081; GO:0006629; GO:0007568; GO:0007584; GO:0008106; GO:0008284; GO:0009410; GO:0014070; GO:0016020; GO:0016620; GO:0018479; GO:0051384; GO:0051591 43460 XM_029332956.2 102 26 64 77 198 Q09470 2.35e-119 Potassium voltage-gated channel subfamily A member 1 (Voltage-gated K(+) channel HuKI) (Voltage-gated potassium channel HBK1) (Voltage-gated potassium channel subunit Kv1.1) Homo sapiens (Human) axon development [GO:0061564]; cell communication by electrical coupling [GO:0010644]; cellular response to magnesium ion [GO:0071286]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; corpus callosum development [GO:0022038]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; detection of mechanical stimulus involved in sensory perception of touch [GO:0050976]; hippocampus development [GO:0021766]; magnesium ion homeostasis [GO:0010960]; neuroblast proliferation [GO:0007405]; neuromuscular process [GO:0050905]; neuronal action potential [GO:0019228]; neuronal signal transduction [GO:0023041]; optic nerve development [GO:0021554]; positive regulation of voltage-gated potassium channel activity [GO:1903818]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; protein localization [GO:0008104]; regulation of membrane potential [GO:0042391]; regulation of muscle contraction [GO:0006937]; startle response [GO:0001964] GO:0001964; GO:0005249; GO:0005251; GO:0005267; GO:0005783; GO:0005829; GO:0005886; GO:0006813; GO:0006937; GO:0007268; GO:0007405; GO:0008076; GO:0008104; GO:0009986; GO:0010644; GO:0010960; GO:0015079; GO:0016020; GO:0016324; GO:0019228; GO:0021554; GO:0021766; GO:0021987; GO:0022038; GO:0023041; GO:0030054; GO:0030425; GO:0031410; GO:0033270; GO:0042391; GO:0042734; GO:0043025; GO:0043194; GO:0043204; GO:0043679; GO:0044224; GO:0044305; GO:0045202; GO:0045211; GO:0050905; GO:0050966; GO:0050976; GO:0051260; GO:0061564; GO:0070161; GO:0071286; GO:0071805; GO:0097718; GO:0098978; GO:0099508; GO:1903818; GO:1905030 43461 XM_044328459.1 747 151 225 605 409 Q96HU1 0 Small G protein signaling modulator 3 (Merlin-associated protein) (RUN and TBC1 domain-containing protein 3) (Rab-GTPase-activating protein-like protein) (RabGAPLP) Homo sapiens (Human) activation of GTPase activity [GO:0090630]; cell cycle [GO:0007049]; plasma membrane to endosome transport [GO:0048227]; positive regulation of GTPase activity [GO:0043547]; positive regulation of protein catabolic process [GO:0045732]; Rap protein signal transduction [GO:0032486]; regulation of cell cycle [GO:0051726]; regulation of Rab protein signal transduction [GO:0032483] GO:0005096; GO:0005829; GO:0005921; GO:0007049; GO:0031267; GO:0032483; GO:0032486; GO:0043547; GO:0045732; GO:0048227; GO:0051726; GO:0090630 43462 XM_029335457.2 133 67 136 148 289 Q8C163 4.6e-100 Nuclease EXOG, mitochondrial (EC 3.1.30.-) (Endonuclease G-like 1) (Endo G-like 1) Mus musculus (Mouse) apoptotic DNA fragmentation [GO:0006309] GO:0000014; GO:0003676; GO:0004519; GO:0004521; GO:0005634; GO:0005739; GO:0005743; GO:0006309; GO:0008409; GO:0032991; GO:0046872 43463 XR_006397118.1 150 103 68 180 155 NA NA NA NA NA NA 43464 XM_044316640.1 4 0 0 11 2 NA NA NA NA NA NA 43465 XM_029330347.2 178 173 165 159 114 Q9VPH8 0 Retinoblastoma-binding protein 5 homolog Drosophila melanogaster (Fruit fly) chromatin organization [GO:0006325]; histone H3-K4 methylation [GO:0051568] GO:0006325; GO:0044665; GO:0044666; GO:0048188; GO:0051568 43466 XR_003824833.2 33 12 4 16 69 NA NA NA NA NA NA 43467 XM_029344909.2 300 335 262 524 510 Q54KD0 1.76e-68 TPR repeat-containing protein DDB_G0287407 Dictyostelium discoideum (Social amoeba) NA NA 43468 XM_029332215.2 5 0 4 7 29 Q9Y5X5 5.96e-40 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (G-protein coupled receptor HLWAR77) (Neuropeptide G-protein coupled receptor) Homo sapiens (Human) detection of abiotic stimulus [GO:0009582]; G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0009582; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 43469 XR_006395642.1 1375 858 411 1184 147 NA NA NA NA NA NA 43470 XM_029348536.2 530 427 304 606 647 F7E540 0 Tubulin polyglutamylase TTLL7 (EC 6.3.2.-) (Tubulin--tyrosine ligase-like protein 7) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell differentiation [GO:0030154]; nervous system development [GO:0007399]; protein polyglutamylation [GO:0018095] GO:0005524; GO:0005737; GO:0005874; GO:0005929; GO:0007399; GO:0018095; GO:0030154; GO:0030425; GO:0043204; GO:0046872; GO:0070740 43471 XM_029348536.2 530 427 304 606 647 F7E540 2.93e-52 Tubulin polyglutamylase TTLL7 (EC 6.3.2.-) (Tubulin--tyrosine ligase-like protein 7) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell differentiation [GO:0030154]; nervous system development [GO:0007399]; protein polyglutamylation [GO:0018095] GO:0005524; GO:0005737; GO:0005874; GO:0005929; GO:0007399; GO:0018095; GO:0030154; GO:0030425; GO:0043204; GO:0046872; GO:0070740 43472 XM_029348089.2 78 102 48 141 0 Q3UQ28 1.78e-136 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 43473 XM_029337277.2 85 15 0 13 204 A6NFN3 4.42e-36 RNA binding protein fox-1 homolog 3 (Fox-1 homolog C) (Neuronal nuclei antigen) (NeuN antigen) Homo sapiens (Human) mRNA processing [GO:0006397]; nervous system development [GO:0007399]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380] GO:0000381; GO:0003729; GO:0005634; GO:0005737; GO:0006397; GO:0007399; GO:0008380 43474 XM_044317136.1 139 3 68 59 135 NA NA NA NA NA NA 43475 XM_029348019.2 65 96 24 48 23 NA NA NA NA NA NA 43476 XM_029348947.2 325 285 68 499 69 O54852 2.97e-102 Potassium voltage-gated channel subfamily H member 7 (Ether-a-go-go-related gene potassium channel 3) (ERG-3) (Eag-related protein 3) (Ether-a-go-go-related protein 3) (Voltage-gated potassium channel subunit Kv11.3) Rattus norvegicus (Rat) circadian rhythm [GO:0007623]; membrane repolarization during action potential [GO:0086011]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391] GO:0005242; GO:0005249; GO:0005267; GO:0005886; GO:0006813; GO:0007623; GO:0034765; GO:0042391; GO:0044877; GO:0071805; GO:0086011 43477 XR_006397819.1 38 1 24 36 22 NA NA NA NA NA NA 43478 XM_029348128.2 37 0 0 0 0 Q66GQ5 1.03e-115 Protein REDUCED WALL ACETYLATION 3 (EC 2.3.1.-) Arabidopsis thaliana (Mouse-ear cress) carbohydrate metabolic process [GO:0005975]; plant-type secondary cell wall biogenesis [GO:0009834]; xylan acetylation [GO:1990937]; xylan biosynthetic process [GO:0045492]; xylan metabolic process [GO:0045491]; xyloglucan metabolic process [GO:0010411] GO:0000139; GO:0005794; GO:0005975; GO:0009834; GO:0010411; GO:0016407; GO:0016491; GO:0045491; GO:0045492; GO:1990937 43479 XM_029357434.2 4114 2702 1938 2914 3982 A7Z056 0 Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.4.19.12) (Deubiquitinating enzyme 20) (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20) Bos taurus (Bovine) endocytosis [GO:0006897]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0001664; GO:0004197; GO:0004843; GO:0005737; GO:0005813; GO:0006511; GO:0006897; GO:0008270; GO:0008277; GO:0016579; GO:0048471; GO:0070536; GO:0071108 43480 XM_029357094.2 197 263 151 157 253 NA NA NA NA NA NA 43481 XM_029338548.2 712 715 1042 818 751 Q8R087 1.53e-105 Beta-1,4-galactosyltransferase 7 (Beta-1,4-GalTase 7) (Beta4Gal-T7) (b4Gal-T7) (EC 2.4.1.-) (Proteoglycan UDP-galactose:beta-xylose beta1,4-galactosyltransferase I) (UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 7) (UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 7) (UDP-galactose:beta-xylose beta-1,4-galactosyltransferase) (XGPT) (XGalT-1) (Xylosylprotein 4-beta-galactosyltransferase) (EC 2.4.1.133) (Xylosylprotein beta-1,4-galactosyltransferase) Mus musculus (Mouse) carbohydrate metabolic process [GO:0005975]; glycosaminoglycan biosynthetic process [GO:0006024]; glycosylation [GO:0070085]; negative regulation of fibroblast proliferation [GO:0048147]; protein N-linked glycosylation [GO:0006487]; proteoglycan biosynthetic process [GO:0030166]; proteoglycan metabolic process [GO:0006029]; supramolecular fiber organization [GO:0097435] GO:0003831; GO:0005794; GO:0005975; GO:0006024; GO:0006029; GO:0006487; GO:0008378; GO:0016020; GO:0030145; GO:0030166; GO:0032580; GO:0046525; GO:0048147; GO:0070085; GO:0097435 43482 XM_044307644.1 9 0 2 0 9 NA NA NA NA NA NA 43483 XM_029340026.2 150 59 33 114 95 Q5H8A4 1.01e-171 GPI ethanolamine phosphate transferase 2 (EC 2.-.-.-) (GPI7 homolog) (hGPI7) (Phosphatidylinositol-glycan biosynthesis class G protein) (PIG-G) Homo sapiens (Human) GPI anchor biosynthetic process [GO:0006506]; preassembly of GPI anchor in ER membrane [GO:0016254] GO:0005783; GO:0005789; GO:0006506; GO:0016020; GO:0016254; GO:0016740; GO:0016780; GO:0051267 43484 XM_029327182.2 514 738 292 649 560 Q5M7G4 1.2e-168 Adenylate kinase 8 (AK 8) (EC 2.7.4.3) (EC 2.7.4.6) (ATP-AMP transphosphorylase 8) Xenopus laevis (African clawed frog) nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142] GO:0004017; GO:0004127; GO:0004550; GO:0005524; GO:0005829; GO:0006165; GO:0009142 43485 XM_044316155.1 1 0 0 0 46 NA NA NA NA NA NA 43486 XM_029328794.2 1095 1374 1249 1316 962 P27615 1.37e-85 Lysosome membrane protein 2 (85 kDa lysosomal membrane sialoglycoprotein) (LGP85) (CD36 antigen-like 2) (Lysosome membrane protein II) (LIMP II) (Scavenger receptor class B member 2) (CD antigen CD36) Rattus norvegicus (Rat) aminophospholipid transport [GO:0015917]; gene expression [GO:0010467]; positive regulation of neuron projection development [GO:0010976]; protein targeting to lysosome [GO:0006622]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular carbohydrate catabolic process [GO:0043471]; regulation of glucosylceramidase activity [GO:1905123]; sensory perception of sound [GO:0007605] GO:0001786; GO:0005044; GO:0005737; GO:0005765; GO:0005886; GO:0006622; GO:0006898; GO:0007605; GO:0010467; GO:0010976; GO:0015485; GO:0015917; GO:0019899; GO:0030666; GO:0031210; GO:0038024; GO:0042803; GO:0043202; GO:0043471; GO:0051087; GO:1905123 43487 XM_029327759.2 945 1319 714 1084 379 P53806 1.82e-34 Calcipressin-like protein (Down syndrome candidate region 1-like protein) (Regulator of calcineurin) Caenorhabditis elegans calcium-mediated signaling [GO:0019722]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of nematode male tail tip morphogenesis [GO:0110039]; response to hermaphrodite contact [GO:0034606]; thermosensory behavior [GO:0040040]; vulval location [GO:0034608] GO:0003676; GO:0004865; GO:0005634; GO:0005737; GO:0008597; GO:0019722; GO:0030346; GO:0032515; GO:0034606; GO:0034608; GO:0040040; GO:0110039 43488 XM_029333631.2 572 191 569 76 154 Q13233 1.12e-116 Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1) Homo sapiens (Human) cellular response to mechanical stimulus [GO:0071260]; Fc-epsilon receptor signaling pathway [GO:0038095]; protein phosphorylation [GO:0006468] GO:0004672; GO:0004674; GO:0004709; GO:0005524; GO:0005737; GO:0005829; GO:0006468; GO:0008270; GO:0019901; GO:0038095; GO:0071260; GO:0106310 43489 XM_029333631.2 572 191 569 76 154 Q13233 2.9e-111 Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1) Homo sapiens (Human) cellular response to mechanical stimulus [GO:0071260]; Fc-epsilon receptor signaling pathway [GO:0038095]; protein phosphorylation [GO:0006468] GO:0004672; GO:0004674; GO:0004709; GO:0005524; GO:0005737; GO:0005829; GO:0006468; GO:0008270; GO:0019901; GO:0038095; GO:0071260; GO:0106310 43490 XM_044321506.1 124 77 59 300 315 NA NA NA NA NA NA 43491 XM_044311743.1 156 82 116 164 162 Q08BW0 6.83e-100 OTU domain-containing protein 5-A (EC 3.4.19.12) (Deubiquitinating enzyme A) (DUBA) Danio rerio (Zebrafish) (Brachydanio rerio) protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; response to lipopolysaccharide [GO:0032496] GO:0004843; GO:0016579; GO:0032496; GO:0061578; GO:0070536; GO:0071108 43492 XR_003828579.2 54 30 31 60 128 NA NA NA NA NA NA 43493 XM_029338463.2 253 172 135 221 348 Q84JE8 5.14e-48 Polynucleotide 3'-phosphatase ZDP (EC 3.1.3.32) (DNA nick sensor protein) Arabidopsis thaliana (Mouse-ear cress) DNA demethylation [GO:0080111]; DNA repair [GO:0006281]; nucleotide phosphorylation [GO:0046939] GO:0003690; GO:0005654; GO:0006281; GO:0008270; GO:0046403; GO:0046404; GO:0046939; GO:0080111 43494 XM_044307540.1 0 2 0 10 8 NA NA NA NA NA NA 43495 XR_006396501.1 121 7233 191 7752 1229 P16092 1.05e-70 Fibroblast growth factor receptor 1 (FGFR-1) (bFGF-R-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (MFR) (Proto-oncogene c-Fgr) (CD antigen CD331) Mus musculus (Mouse) angiogenesis [GO:0001525]; auditory receptor cell development [GO:0060117]; blood vessel morphogenesis [GO:0048514]; brain development [GO:0007420]; branching involved in salivary gland morphogenesis [GO:0060445]; calcium ion homeostasis [GO:0055074]; cardiac muscle cell proliferation [GO:0060038]; cell maturation [GO:0048469]; cell population proliferation [GO:0008283]; cementum mineralization [GO:0071529]; central nervous system neuron development [GO:0021954]; chondrocyte differentiation [GO:0002062]; diphosphate metabolic process [GO:0071344]; ear development [GO:0043583]; embryonic limb morphogenesis [GO:0030326]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; gene expression [GO:0010467]; generation of neurons [GO:0048699]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; lung development [GO:0030324]; lung-associated mesenchyme development [GO:0060484]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell proliferation [GO:0010463]; midbrain development [GO:0030901]; middle ear morphogenesis [GO:0042474]; motogenic signaling involved in postnatal olfactory bulb interneuron migration [GO:0021837]; negative regulation of fibroblast growth factor production [GO:0090272]; negative regulation of gene expression [GO:0010629]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron projection development [GO:0031175]; orbitofrontal cortex development [GO:0021769]; organ induction [GO:0001759]; outer ear morphogenesis [GO:0042473]; paraxial mesoderm development [GO:0048339]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of hepatic stellate cell activation [GO:2000491]; positive regulation of inflammatory response [GO:0050729]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway [GO:0090080]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of mitotic cell cycle DNA replication [GO:1903465]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neuron projection development [GO:0010976]; positive regulation of parathyroid hormone secretion [GO:2000830]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; protein autophosphorylation [GO:0046777]; regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling [GO:0060665]; regulation of cell population proliferation [GO:0042127]; regulation of epithelial cell proliferation [GO:0050678]; regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001239]; regulation of gene expression [GO:0010468]; regulation of lateral mesodermal cell fate specification [GO:0048378]; regulation of phosphate transport [GO:0010966]; regulation of phosphorus metabolic process [GO:0051174]; regulation of sensory perception of pain [GO:0051930]; regulation of stem cell proliferation [GO:0072091]; response to sodium phosphate [GO:1904383]; salivary gland morphogenesis [GO:0007435]; sensory perception of sound [GO:0007605]; stem cell differentiation [GO:0048863]; stem cell population maintenance [GO:0019827]; stem cell proliferation [GO:0072089]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; vasculogenesis involved in coronary vascular morphogenesis [GO:0060979]; ventricular zone neuroblast division [GO:0021847]; vitamin D3 metabolic process [GO:0070640] GO:0000122; GO:0001525; GO:0001657; GO:0001701; GO:0001759; GO:0001837; GO:0002053; GO:0002062; GO:0004713; GO:0004714; GO:0005007; GO:0005102; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0007169; GO:0007420; GO:0007435; GO:0007605; GO:0008201; GO:0008283; GO:0008284; GO:0008543; GO:0010463; GO:0010467; GO:0010468; GO:0010629; GO:0010763; GO:0010863; GO:0010966; GO:0010976; GO:0017134; GO:0018108; GO:0019827; GO:0021769; GO:0021837; GO:0021847; GO:0021954; GO:0030324; GO:0030326; GO:0030901; GO:0031175; GO:0031410; GO:0033674; GO:0035607; GO:0042127; GO:0042169; GO:0042472; GO:0042473; GO:0042474; GO:0042802; GO:0042803; GO:0043235; GO:0043406; GO:0043410; GO:0043536; GO:0043583; GO:0044877; GO:0045597; GO:0045666; GO:0045668; GO:0045787; GO:0045944; GO:0046777; GO:0048339; GO:0048378; GO:0048469; GO:0048471; GO:0048514; GO:0048699; GO:0048762; GO:0048863; GO:0050678; GO:0050729; GO:0050839; GO:0051174; GO:0051897; GO:0051930; GO:0055074; GO:0060038; GO:0060045; GO:0060117; GO:0060445; GO:0060484; GO:0060665; GO:0060979; GO:0070640; GO:0071344; GO:0071529; GO:0072089; GO:0072091; GO:0090080; GO:0090272; GO:0090722; GO:1903465; GO:1904383; GO:1905564; GO:2000491; GO:2000546; GO:2000648; GO:2000830; GO:2001239 43496 XM_044308077.1 48 69 25 12 25 Q6P4F7 1.48e-32 Rho GTPase-activating protein 11A (Rho-type GTPase-activating protein 11A) Homo sapiens (Human) positive regulation of GTPase activity [GO:0043547]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] GO:0005096; GO:0005634; GO:0005829; GO:0007165; GO:0043547; GO:0051056 43497 XM_044320603.1 0 6 0 0 4 NA NA NA NA NA NA 43498 XM_044322388.1 0 0 0 0 8 NA NA NA NA NA NA 43499 XR_006395139.1 65 60 17 18 81 NA NA NA NA NA NA 43500 XM_044314054.1 1035 784 678 1248 1003 Q14746 1.89e-172 Conserved oligomeric Golgi complex subunit 2 (COG complex subunit 2) (Component of oligomeric Golgi complex 2) (Low density lipoprotein receptor defect C-complementing protein) Homo sapiens (Human) glycosylation [GO:0070085]; Golgi organization [GO:0007030]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein transport [GO:0015031]; retrograde transport, vesicle recycling within Golgi [GO:0000301] GO:0000139; GO:0000301; GO:0005795; GO:0005829; GO:0006891; GO:0007030; GO:0015031; GO:0017119; GO:0032588; GO:0044877; GO:0070085 43501 XM_044325695.1 71 0 29 1 75 NA NA NA NA NA NA 43502 XM_044322252.1 39 0 102 0 0 NA NA NA NA NA NA 43503 XM_029330385.2 56 11 0 102 57 Q8WUK0 2.73e-37 Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 (EC 3.1.3.27) (PTEN-like phosphatase) (Phosphoinositide lipid phosphatase) (Protein-tyrosine phosphatase mitochondrial 1) (EC 3.1.3.16, EC 3.1.3.48) Homo sapiens (Human) cardiolipin biosynthetic process [GO:0032049]; protein dephosphorylation [GO:0006470]; regulation of intrinsic apoptotic signaling pathway [GO:2001242] GO:0004439; GO:0004725; GO:0005634; GO:0005739; GO:0005743; GO:0006470; GO:0008138; GO:0008962; GO:0017018; GO:0032049; GO:2001242 43504 XM_044309131.1 71 0 13 99 0 NA NA NA NA NA NA 43505 XM_029348478.2 214 581 48 412 60 Q8K596 4.74e-73 Sodium/calcium exchanger 2 (Na(+)/Ca(2+)-exchange protein 2) (Solute carrier family 8 member 2) Mus musculus (Mouse) calcium ion export across plasma membrane [GO:1990034]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport into cytosol [GO:0060402]; cell communication [GO:0007154]; cellular calcium ion homeostasis [GO:0006874]; cognition [GO:0050890]; learning [GO:0007612]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; metal ion transport [GO:0030001]; modulation of excitatory postsynaptic potential [GO:0098815]; neuron cellular homeostasis [GO:0070050]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; regulation of action potential firing pattern [GO:0099608]; regulation of calcineurin-mediated signaling [GO:0106056]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; response to ischemia [GO:0002931]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814]; synapse organization [GO:0050808] GO:0002931; GO:0005432; GO:0005516; GO:0005739; GO:0005874; GO:0005886; GO:0006814; GO:0006874; GO:0007154; GO:0007611; GO:0007612; GO:0007613; GO:0010468; GO:0014069; GO:0015081; GO:0015085; GO:0016020; GO:0016323; GO:0030001; GO:0030424; GO:0030425; GO:0035725; GO:0042383; GO:0042995; GO:0043025; GO:0043197; GO:0043679; GO:0045202; GO:0045211; GO:0046872; GO:0048172; GO:0050808; GO:0050890; GO:0051480; GO:0060291; GO:0060402; GO:0070050; GO:0070588; GO:0071902; GO:0098703; GO:0098793; GO:0098794; GO:0098815; GO:0099608; GO:0106056; GO:1905060; GO:1990034 43506 XM_029348478.2 214 581 48 412 60 Q8K596 1.21e-43 Sodium/calcium exchanger 2 (Na(+)/Ca(2+)-exchange protein 2) (Solute carrier family 8 member 2) Mus musculus (Mouse) calcium ion export across plasma membrane [GO:1990034]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport into cytosol [GO:0060402]; cell communication [GO:0007154]; cellular calcium ion homeostasis [GO:0006874]; cognition [GO:0050890]; learning [GO:0007612]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; metal ion transport [GO:0030001]; modulation of excitatory postsynaptic potential [GO:0098815]; neuron cellular homeostasis [GO:0070050]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; regulation of action potential firing pattern [GO:0099608]; regulation of calcineurin-mediated signaling [GO:0106056]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; response to ischemia [GO:0002931]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814]; synapse organization [GO:0050808] GO:0002931; GO:0005432; GO:0005516; GO:0005739; GO:0005874; GO:0005886; GO:0006814; GO:0006874; GO:0007154; GO:0007611; GO:0007612; GO:0007613; GO:0010468; GO:0014069; GO:0015081; GO:0015085; GO:0016020; GO:0016323; GO:0030001; GO:0030424; GO:0030425; GO:0035725; GO:0042383; GO:0042995; GO:0043025; GO:0043197; GO:0043679; GO:0045202; GO:0045211; GO:0046872; GO:0048172; GO:0050808; GO:0050890; GO:0051480; GO:0060291; GO:0060402; GO:0070050; GO:0070588; GO:0071902; GO:0098703; GO:0098793; GO:0098794; GO:0098815; GO:0099608; GO:0106056; GO:1905060; GO:1990034 43507 XM_044319501.1 1 0 0 11 0 O60290 1.86e-53 Zinc finger protein 862 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006355; GO:0046872; GO:0046983 43508 XM_029331049.2 535 388 255 396 435 Q08E20 1.05e-148 S-formylglutathione hydrolase (FGH) (EC 3.1.2.12) (Esterase D) Bos taurus (Bovine) formaldehyde catabolic process [GO:0046294] GO:0005829; GO:0018738; GO:0031410; GO:0046294 43509 XM_044313266.1 85 77 135 89 53 A0A1L8FDW4 9.34e-41 Peroxisomal targeting signal 1 receptor (PTS1 receptor) (PTS1R) (PTS1-BP) (Peroxin-5) Xenopus laevis (African clawed frog) pexophagy [GO:0000425]; protein import into peroxisome matrix, receptor recycling [GO:0016562]; protein import into peroxisome matrix, substrate release [GO:0044721]; protein import into peroxisome matrix, translocation [GO:0016561] GO:0000425; GO:0005052; GO:0005782; GO:0005829; GO:0016561; GO:0016562; GO:0044721; GO:0140597 43510 XM_044315586.1 161 42 183 104 95 NA NA NA NA NA NA 43511 XM_029350409.2 0 0 4 0 6 Q9CUX1 4.59e-31 52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (THAP domain-containing protein 0) (THAP domain-containing protein 12) Mus musculus (Mouse) NA GO:0003677; GO:0005634; GO:0046872; GO:0046983 43512 XM_044320961.1 184 1 0 1 1 NA NA NA NA NA NA 43513 XR_003826234.2 0 0 0 6 0 NA NA NA NA NA NA 43514 XM_044326260.1 8 5 2 49 12 NA NA NA NA NA NA 43515 XM_029343086.2 2600 4696 2268 3210 2920 O43399 4.72e-21 Tumor protein D54 (hD54) (Tumor protein D52-like 2) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; regulation of cell population proliferation [GO:0042127] GO:0003723; GO:0005737; GO:0005975; GO:0042127; GO:0042803; GO:0048471 43516 XM_044320507.1 13 0 8 18 80 NA NA NA NA NA NA 43517 XM_029345038.2 150 175 0 0 0 NA NA NA NA NA NA 43518 XM_044316874.1 0 19 0 0 0 NA NA NA NA NA NA 43519 XM_044306781.1 0 0 0 0 6 Q5SY80 5.39e-21 Cation channel sperm-associated auxiliary subunit epsilon (CatSper-epsilon) (CatSperepsilon) Homo sapiens (Human) flagellated sperm motility [GO:0030317]; sperm capacitation [GO:0048240] GO:0030317; GO:0036128; GO:0048240; GO:0097228 43520 XM_029338600.2 353 191 106 347 295 Q08BC4 5.4e-115 Sperm-tail PG-rich repeat-containing protein 2 Danio rerio (Zebrafish) (Brachydanio rerio) NA NA 43521 XM_029333846.2 9 14 0 0 0 NA NA NA NA NA NA 43522 XM_044322611.1 354 185 178 376 211 Q9D2I5 0 LisH domain-containing protein ARMC9 Mus musculus (Mouse) cilium assembly [GO:0060271]; positive regulation of smoothened signaling pathway [GO:0045880] GO:0005737; GO:0005814; GO:0005929; GO:0036064; GO:0045880; GO:0060271; GO:0097542 43523 XM_029331470.2 9895 13223 6610 11124 8388 Q5F464 6.18e-77 Lipoma-preferred partner homolog Gallus gallus (Chicken) cell-cell adhesion [GO:0098609] GO:0001725; GO:0005634; GO:0005737; GO:0005925; GO:0046872; GO:0098609 43524 XM_044314673.1 163 140 139 43 402 NA NA NA NA NA NA 43525 XM_029345382.2 525 324 211 292 359 Q5ZKJ5 0 Transmembrane protein 180 (Major facilitator superfamily domain-containing 13A) Gallus gallus (Chicken) NA GO:0016020 43526 XR_006393086.1 12 3 32 0 12 NA NA NA NA NA NA 43527 XM_029340283.2 232 37 223 82 58 Q64676 7.67e-87 2-hydroxyacylsphingosine 1-beta-galactosyltransferase (EC 2.4.1.47) (Ceramide UDP-galactosyltransferase) (Cerebroside synthase) (UDP-galactose-ceramide galactosyltransferase) Mus musculus (Mouse) cytoskeleton organization [GO:0007010]; galactosylceramide biosynthetic process [GO:0006682]; glycolipid biosynthetic process [GO:0009247]; myelination [GO:0042552]; neuron projection morphogenesis [GO:0048812]; paranodal junction assembly [GO:0030913]; protein localization to paranode region of axon [GO:0002175] GO:0002175; GO:0003851; GO:0005783; GO:0006682; GO:0007010; GO:0008120; GO:0008489; GO:0009247; GO:0016020; GO:0030913; GO:0042552; GO:0047263; GO:0048812 43528 XM_044307936.1 79 37 0 76 95 NA NA NA NA NA NA 43529 XR_006396728.1 7 0 0 1 24 NA NA NA NA NA NA 43530 XM_029338803.2 0 0 0 169 0 B3EWZ7 2.79e-68 Threonine-rich protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 43531 XM_029344694.2 525 254 263 392 345 Q502B3 2.28e-111 UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2 (Beta-1,3-GalNAc-T2) (EC 2.4.1.313) (Beta-1,3-N-acetylgalactosaminyltransferase II) Danio rerio (Zebrafish) (Brachydanio rerio) protein glycosylation [GO:0006486]; protein O-linked glycosylation [GO:0006493] GO:0000139; GO:0005783; GO:0006486; GO:0006493; GO:0008194; GO:0008376; GO:0016757 43532 XM_044311156.1 0 2 13 0 0 NA NA NA NA NA NA 43533 XM_029339292.2 441 457 485 1202 631 Q17R09 0 Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 (EC 3.6.4.13) (ATP-dependent RNA helicase DHX38) (DEAH box protein 38) Bos taurus (Bovine) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0003723; GO:0003724; GO:0005524; GO:0005681; GO:0016887; GO:0071013 43534 XM_029337972.2 887 241 381 345 464 NA NA NA NA NA NA 43535 XM_029356791.2 111 63 36 27 415 Q7M3E1 1.88e-43 Chymotrypsin-C (EC 3.4.21.2) (bPTLP) Bos taurus (Bovine) proteolysis [GO:0006508] GO:0004252; GO:0005615; GO:0006508 43536 XR_006394792.1 0 0 5 3 52 NA NA NA NA NA NA 43537 XM_044319487.1 409 174 58 232 256 P0CI65 2.03e-47 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 43538 XM_044319487.1 409 174 58 232 256 P0CI65 6.65e-44 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 43539 XM_044319487.1 409 174 58 232 256 P0CI65 8.16e-44 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 43540 XM_044319487.1 409 174 58 232 256 P0CI65 8.3e-44 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 43541 XM_044319487.1 409 174 58 232 256 P0CI65 4.7e-42 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 43542 XM_044319487.1 409 174 58 232 256 P0CI65 5.06e-33 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 43543 XM_044319487.1 409 174 58 232 256 P0CI65 4.5e-30 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 43544 XM_044319487.1 409 174 58 232 256 P0CI65 9.92e-24 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 43545 XM_029350891.2 785 495 399 496 474 Q9H7F4 2.78e-105 Transmembrane protein 185B (Protein FAM11B) Homo sapiens (Human) NA GO:0016020 43546 XR_003826973.2 59 25 12 44 42 NA NA NA NA NA NA 43547 XM_044322673.1 10 58 7 5 1 A1L2Q8 1.57e-59 Pyrroline-5-carboxylate reductase 3 (P5C reductase 3) (P5CR 3) (EC 1.5.1.2) (Pyrroline-5-carboxylate reductase-like protein) Xenopus laevis (African clawed frog) L-proline biosynthetic process [GO:0055129] GO:0004735; GO:0005829; GO:0055129 43548 XM_029333930.2 49 94 0 107 54 NA NA NA NA NA NA 43549 XM_029340573.2 43 78 35 28 21 NA NA NA NA NA NA 43550 XR_006396578.1 42 58 21 103 92 NA NA NA NA NA NA 43551 XM_044321182.1 5 0 7 0 0 P70031 9.27e-34 Cholecystokinin receptor (CCK-XLR) Xenopus laevis (African clawed frog) NA GO:0004930; GO:0005886 43552 XR_006394786.1 11 3 10 0 22 NA NA NA NA NA NA 43553 XM_044329086.1 33 6 2 26 7 NA NA NA NA NA NA 43554 XM_044321610.1 1824 1088 1311 1457 1942 Q9Y4A5 0 Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog) Homo sapiens (Human) chromatin organization [GO:0006325]; DNA repair [GO:0006281]; histone acetylation [GO:0016573]; histone H2A acetylation [GO:0043968]; histone H3 acetylation [GO:0043966]; histone H4 acetylation [GO:0043967]; monoubiquitinated histone deubiquitination [GO:0035521]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of DNA repair [GO:0006282]; regulation of DNA-templated transcription [GO:0006355]; regulation of double-strand break repair [GO:2000779]; regulation of RNA splicing [GO:0043484]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000124; GO:0000786; GO:0000812; GO:0003712; GO:0005634; GO:0005654; GO:0005794; GO:0006281; GO:0006282; GO:0006325; GO:0006355; GO:0006357; GO:0016573; GO:0033276; GO:0035267; GO:0035521; GO:0035522; GO:0042981; GO:0043484; GO:0043966; GO:0043967; GO:0043968; GO:0045893; GO:0051726; GO:1905168; GO:2000779 43555 XM_044321610.1 1824 1088 1311 1457 1942 Q9Y4A5 0 Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog) Homo sapiens (Human) chromatin organization [GO:0006325]; DNA repair [GO:0006281]; histone acetylation [GO:0016573]; histone H2A acetylation [GO:0043968]; histone H3 acetylation [GO:0043966]; histone H4 acetylation [GO:0043967]; monoubiquitinated histone deubiquitination [GO:0035521]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of DNA repair [GO:0006282]; regulation of DNA-templated transcription [GO:0006355]; regulation of double-strand break repair [GO:2000779]; regulation of RNA splicing [GO:0043484]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000124; GO:0000786; GO:0000812; GO:0003712; GO:0005634; GO:0005654; GO:0005794; GO:0006281; GO:0006282; GO:0006325; GO:0006355; GO:0006357; GO:0016573; GO:0033276; GO:0035267; GO:0035521; GO:0035522; GO:0042981; GO:0043484; GO:0043966; GO:0043967; GO:0043968; GO:0045893; GO:0051726; GO:1905168; GO:2000779 43556 XM_029340738.2 31827 29742 13602 21031 17574 V5NBV4 1.09e-28 Tropomyosin Mac r 1.0101 (Major allergen Mac r 1.0101) (allergen Mac r 1.0101) Macrobrachium rosenbergii (Giant fresh water prawn) locomotion [GO:0040011]; muscle system process [GO:0003012]; regulation of muscle contraction [GO:0006937] GO:0003012; GO:0006937; GO:0040011; GO:0042803 43557 XM_044320644.1 0 0 3 13 12 NA NA NA NA NA NA 43558 XM_044311282.1 60 19 29 38 48 NA NA NA NA NA NA 43559 XM_029349451.2 0 6 9 10 6 P30543 1.35e-23 Adenosine receptor A2a Rattus norvegicus (Rat) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; apoptotic signaling pathway [GO:0097190]; astrocyte activation [GO:0048143]; eating behavior [GO:0042755]; excitatory postsynaptic potential [GO:0060079]; G protein-coupled adenosine receptor signaling pathway [GO:0001973]; G protein-coupled receptor signaling pathway [GO:0007186]; inhibitory postsynaptic potential [GO:0060080]; locomotory behavior [GO:0007626]; membrane depolarization [GO:0051899]; negative regulation of alpha-beta T cell activation [GO:0046636]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of inflammatory response [GO:0050728]; negative regulation of locomotion [GO:0040013]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of vascular permeability [GO:0043116]; neuron projection morphogenesis [GO:0048812]; positive regulation of acetylcholine secretion, neurotransmission [GO:0014057]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of circadian sleep/wake cycle, sleep [GO:0045938]; positive regulation of glutamate secretion [GO:0014049]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of protein secretion [GO:0050714]; positive regulation of renal sodium excretion [GO:0035815]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of urine volume [GO:0035810]; prepulse inhibition [GO:0060134]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; regulation of calcium ion transport [GO:0051924]; regulation of DNA-templated transcription [GO:0006355]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of norepinephrine secretion [GO:0014061]; response to alkaloid [GO:0043279]; response to amphetamine [GO:0001975]; response to caffeine [GO:0031000]; response to inorganic substance [GO:0010035]; response to purine-containing compound [GO:0014074]; response to xenobiotic stimulus [GO:0009410]; synaptic transmission, cholinergic [GO:0007271]; synaptic transmission, dopaminergic [GO:0001963]; synaptic transmission, glutamatergic [GO:0035249]; vasodilation [GO:0042311] GO:0000139; GO:0001609; GO:0001963; GO:0001973; GO:0001975; GO:0004930; GO:0005886; GO:0006355; GO:0006469; GO:0007186; GO:0007189; GO:0007205; GO:0007271; GO:0007626; GO:0008285; GO:0008289; GO:0009410; GO:0010035; GO:0012505; GO:0014049; GO:0014057; GO:0014061; GO:0014069; GO:0014074; GO:0016020; GO:0019899; GO:0030424; GO:0030425; GO:0030673; GO:0031000; GO:0031802; GO:0032230; GO:0032279; GO:0035249; GO:0035810; GO:0035815; GO:0040013; GO:0042311; GO:0042734; GO:0042755; GO:0042802; GO:0043025; GO:0043116; GO:0043154; GO:0043279; GO:0043524; GO:0044877; GO:0045211; GO:0045938; GO:0046636; GO:0048143; GO:0048786; GO:0048812; GO:0050714; GO:0050728; GO:0051393; GO:0051881; GO:0051899; GO:0051924; GO:0051968; GO:0060079; GO:0060080; GO:0060134; GO:0097190; GO:0098978; GO:0099171; GO:1900273; GO:2001235 43560 XR_006391277.1 21 34 50 18 28 NA NA NA NA NA NA 43561 XM_029343578.2 198 533 158 289 581 P47862 1.09e-82 Aquaporin-3 (AQP-3) (31.4 kDa water channel protein) (Aquaglyceroporin-3) Rattus norvegicus (Rat) cellular response to hypoxia [GO:0071456]; cellular response to oxygen-glucose deprivation [GO:0090650]; establishment of localization in cell [GO:0051649]; glycerol transmembrane transport [GO:0015793]; odontogenesis [GO:0042476]; polyol transmembrane transport [GO:0015791]; positive regulation of immune system process [GO:0002684]; renal water absorption [GO:0070295]; response to retinoic acid [GO:0032526]; urea transport [GO:0015840]; water transport [GO:0006833] GO:0002684; GO:0005737; GO:0005886; GO:0005911; GO:0006833; GO:0015166; GO:0015204; GO:0015250; GO:0015254; GO:0015791; GO:0015793; GO:0015840; GO:0016323; GO:0032526; GO:0042476; GO:0042802; GO:0051649; GO:0070295; GO:0071456; GO:0090650 43562 XM_044310185.1 115 110 71 104 136 Q96AJ9 3.2e-42 Vesicle transport through interaction with t-SNAREs homolog 1A (Vesicle transport v-SNARE protein Vti1-like 2) (Vti1-rp2) Homo sapiens (Human) autophagy [GO:0006914]; endocytic recycling [GO:0032456]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to vacuole transport [GO:0006896]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; macroautophagy [GO:0016236]; retrograde transport, endosome to Golgi [GO:0042147]; vesicle fusion [GO:0006906]; vesicle fusion with Golgi apparatus [GO:0048280]; voluntary musculoskeletal movement [GO:0050882] GO:0000139; GO:0000149; GO:0005484; GO:0005768; GO:0005776; GO:0005789; GO:0005794; GO:0005829; GO:0006886; GO:0006888; GO:0006891; GO:0006896; GO:0006906; GO:0006914; GO:0008021; GO:0012507; GO:0016236; GO:0030136; GO:0031201; GO:0031902; GO:0032456; GO:0032588; GO:0042147; GO:0043025; GO:0043231; GO:0044306; GO:0048280; GO:0048471; GO:0050882 43563 XM_029330591.2 131 375 206 86 66 O95395 6.21e-63 Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 (EC 2.4.1.102) (EC 2.4.1.148) (EC 2.4.1.150) (C2GnT-mucin type) (C2GnT-M) (hC2GnT-M) (Core 2/core 4 beta-1,6-N-acetylglucosaminyltransferase) (C2/4GnT) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; intestinal absorption [GO:0050892]; kidney morphogenesis [GO:0060993]; O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493]; tissue morphogenesis [GO:0048729] GO:0000139; GO:0003829; GO:0005975; GO:0006493; GO:0008109; GO:0008375; GO:0016020; GO:0016266; GO:0048729; GO:0050892; GO:0060993; GO:0070062; GO:0106325; GO:0106326 43564 XM_044324932.1 10 2 0 5 25 NA NA NA NA NA NA 43565 XM_029350479.2 53 25 69 66 94 NA NA NA NA NA NA 43566 XM_029343717.2 8 0 3 0 0 NA NA NA NA NA NA 43567 XM_029331110.2 20 4 39 7 115 NA NA NA NA NA NA 43568 XM_044321026.1 1043 424 846 670 739 Q9UGM3 5.77e-61 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 43569 XM_044321026.1 1043 424 846 670 739 Q9UGM3 4.51e-58 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 43570 XM_044321026.1 1043 424 846 670 739 Q9UGM3 2.54e-57 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 43571 XM_044321026.1 1043 424 846 670 739 Q9UGM3 2.79e-57 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 43572 XM_044321026.1 1043 424 846 670 739 Q9UGM3 3.5e-57 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 43573 XM_044321026.1 1043 424 846 670 739 Q9UGM3 1.18e-56 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 43574 XM_044321026.1 1043 424 846 670 739 Q9UGM3 2.79e-56 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 43575 XM_044321026.1 1043 424 846 670 739 Q9UGM3 3.34e-55 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 43576 XM_044321026.1 1043 424 846 670 739 Q9UGM3 2.59e-24 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 43577 XM_044321026.1 1043 424 846 670 739 Q9UGM3 7.07e-22 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 43578 XM_044321026.1 1043 424 846 670 739 Q9UGM3 7.07e-22 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 43579 XM_044321026.1 1043 424 846 670 739 Q9UGM3 7.07e-22 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 43580 XM_044321026.1 1043 424 846 670 739 Q9UGM3 1.45e-21 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 43581 XM_044321026.1 1043 424 846 670 739 Q9UGM3 4.61e-21 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 43582 XM_044321026.1 1043 424 846 670 739 Q9UGM3 6.72e-21 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 43583 XM_029341977.2 505 48 0 0 218 Q9CYL5 5.4e-33 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Mus musculus (Mouse) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070374 43584 XM_029341977.2 505 48 0 0 218 Q9CYL5 1.61e-23 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Mus musculus (Mouse) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070374 43585 XR_003825989.2 48 117 47 121 157 NA NA NA NA NA NA 43586 XM_029353337.2 257 173 135 310 145 Q8BHJ9 0 Pre-mRNA-splicing factor SLU7 Mus musculus (Mouse) alternative mRNA splicing, via spliceosome [GO:0000380]; cellular response to heat [GO:0034605]; intracellular protein transport [GO:0006886]; mRNA 3'-splice site recognition [GO:0000389]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375] GO:0000375; GO:0000380; GO:0000386; GO:0000389; GO:0005634; GO:0005654; GO:0005681; GO:0005737; GO:0005829; GO:0006886; GO:0008270; GO:0008380; GO:0016607; GO:0030532; GO:0030628; GO:0034605; GO:0043231; GO:0071013 43587 XM_044328874.1 522 456 266 344 551 Q4UMH6 1.68e-47 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 43588 XM_044328874.1 522 456 266 344 551 Q4UMH6 1.29e-44 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 43589 XM_044328874.1 522 456 266 344 551 Q4UMH6 2.46e-43 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 43590 XM_044328874.1 522 456 266 344 551 Q4UMH6 1.17e-41 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 43591 XM_044328874.1 522 456 266 344 551 Q4UMH6 1.5e-36 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 43592 XM_044328874.1 522 456 266 344 551 Q4UMH6 3.84e-28 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 43593 XM_044316811.1 7 0 0 45 241 Q6ZNA5 2.81e-27 Ferric-chelate reductase 1 (EC 1.-.-.-) (Stromal cell-derived receptor 2) (SDR-2) Homo sapiens (Human) cellular iron ion homeostasis [GO:0006879] GO:0006879; GO:0016020; GO:0016722; GO:0046872 43594 XM_044319715.1 49 48 20 78 51 NA NA NA NA NA NA 43595 XM_044325589.1 13 22 7 8 10 NA NA NA NA NA NA 43596 XM_044312871.1 15 0 0 0 0 NA NA NA NA NA NA 43597 XM_029339881.2 541 644 427 612 496 NA NA NA NA NA NA 43598 XM_029338223.2 57 13 66 28 100 Q60715 3.67e-75 Prolyl 4-hydroxylase subunit alpha-1 (4-PH alpha-1) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1) Mus musculus (Mouse) collagen fibril organization [GO:0030199]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401] GO:0004656; GO:0005506; GO:0005739; GO:0005783; GO:0005788; GO:0016222; GO:0018401; GO:0030199; GO:0031418; GO:0042802; GO:0043231 43599 XM_044320835.1 85 28 15 17 49 E9Q5R7 2e-44 NACHT, LRR and PYD domains-containing protein 12 (Monarch-1) (PYRIN-containing APAF1-like protein 7) (PYPAF7) Mus musculus (Mouse) cellular response to cytokine stimulus [GO:0071345]; dendritic cell migration [GO:0036336]; ERK1 and ERK2 cascade [GO:0070371]; negative regulation of cytokine production [GO:0001818]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of signal transduction [GO:0009968]; negative regulation of Toll signaling pathway [GO:0045751]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of inflammatory response [GO:0050727] GO:0001818; GO:0005524; GO:0005737; GO:0009968; GO:0031953; GO:0032088; GO:0032692; GO:0032715; GO:0036336; GO:0038061; GO:0043122; GO:0043124; GO:0043281; GO:0045345; GO:0045751; GO:0050727; GO:0050728; GO:0070371; GO:0070373; GO:0071345; GO:1901223; GO:1901224 43600 XM_044318704.1 0 0 0 0 7 NA NA NA NA NA NA 43601 XM_044306795.1 98 0 88 77 94 Q7YR35 1.86e-166 Guanine nucleotide-binding protein-like 1 Pan troglodytes (Chimpanzee) NA GO:0003924; GO:0005525 43602 XM_044310887.1 52 8 0 8 18 NA NA NA NA NA NA 43603 XM_029338534.2 51 0 0 31 31 NA NA NA NA NA NA 43604 XR_006393431.1 0 0 3 39 154 Q6DG03 7.55e-38 Cyclin-D-binding Myb-like transcription factor 1 Danio rerio (Zebrafish) (Brachydanio rerio) cell cycle [GO:0007049]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000976; GO:0000978; GO:0000981; GO:0003700; GO:0005634; GO:0006355; GO:0006357; GO:0007049 43605 XM_029339942.2 72 154 68 143 159 Q09081 6.89e-90 Potassium voltage-gated channel subfamily A member 2 (KC22) (Voltage-gated potassium channel subunit Kv1.2) Oryctolagus cuniculus (Rabbit) neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233] GO:0005249; GO:0005251; GO:0005789; GO:0005886; GO:0008076; GO:0014059; GO:0019228; GO:0019233; GO:0021633; GO:0030027; GO:0030424; GO:0030425; GO:0031258; GO:0032809; GO:0033010; GO:0034765; GO:0042734; GO:0043194; GO:0043204; GO:0043679; GO:0044224; GO:0045188; GO:0051260; GO:0071805 43606 XM_029334204.2 71 44 80 38 241 A0JC51 6.4e-65 Zinc finger protein ZIC 4 (XlZic4) (Zinc finger protein of the cerebellum 4) Xenopus laevis (African clawed frog) nervous system development [GO:0007399]; neural crest formation [GO:0014029] GO:0003677; GO:0005634; GO:0007399; GO:0014029; GO:0046872 43607 XM_029349185.2 180 153 68 143 158 A7RV13 3.28e-52 Proteasome assembly chaperone 1 Nematostella vectensis (Starlet sea anemone) proteasome core complex assembly [GO:0080129] GO:0005783; GO:0070628; GO:0080129 43608 XR_003824435.2 267 199 159 242 378 NA NA NA NA NA NA 43609 XM_029328939.2 3519 3178 1978 2535 1869 Q5F478 1.99e-34 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (PP6-ARS-B) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-B) (Ankyrin repeat domain-containing protein 44) Gallus gallus (Chicken) NA NA 43610 XM_029328939.2 3519 3178 1978 2535 1869 Q5F478 1.26e-22 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (PP6-ARS-B) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-B) (Ankyrin repeat domain-containing protein 44) Gallus gallus (Chicken) NA NA 43611 XM_029333895.2 12070 12900 5423 10651 7548 Q66II3 9.3e-88 Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) insulin receptor signaling pathway [GO:0008286]; meiotic cell cycle [GO:0051321] GO:0005154; GO:0005634; GO:0005737; GO:0005768; GO:0005794; GO:0008286; GO:0043560; GO:0051321 43612 XM_029336322.2 47 16 37 22 12 Q5ZLA6 0 Unconventional myosin-Ic (Myosin I beta) (MMI-beta) (MMIb) Gallus gallus (Chicken) actin filament organization [GO:0007015]; vesicle transport along actin filament [GO:0030050] GO:0000146; GO:0005524; GO:0005737; GO:0005886; GO:0005902; GO:0005938; GO:0007015; GO:0015629; GO:0016459; GO:0030050; GO:0031410; GO:0031982; GO:0032587; GO:0051015; GO:0060171 43613 XR_003825187.2 0 3 4 0 11 NA NA NA NA NA NA 43614 XM_044322751.1 0 33 82 39 101 NA NA NA NA NA NA 43615 XM_044308422.1 295 415 227 581 541 NA NA NA NA NA NA 43616 XM_029330459.2 913 467 568 543 354 P61025 1.48e-34 Cyclin-dependent kinases regulatory subunit 1 (CKS-1) (Sid 1334) Mus musculus (Mouse) cell division [GO:0051301]; fibroblast proliferation [GO:0048144]; mitotic cell cycle phase transition [GO:0044772]; regulation of DNA-templated transcription [GO:0006355]; regulation of mitotic cell cycle [GO:0007346] GO:0000307; GO:0006355; GO:0007346; GO:0019005; GO:0019901; GO:0042393; GO:0043130; GO:0044772; GO:0048144; GO:0051301; GO:0061575 43617 XM_044320129.1 4 2 11 2 49 NA NA NA NA NA NA 43618 XR_006395001.1 819 151 114 481 752 NA NA NA NA NA NA 43619 XM_044317259.1 0 9 7 26 0 NA NA NA NA NA NA 43620 XM_044328539.1 27 25 66 65 16 Q5TZE1 2.78e-52 BTB/POZ domain-containing protein 6-B Danio rerio (Zebrafish) (Brachydanio rerio) neurogenesis [GO:0022008] GO:0005634; GO:0005829; GO:0022008 43621 XR_003824639.2 729 632 79 271 198 NA NA NA NA NA NA 43622 XM_044321833.1 35 15 40 3 7 Q9D6D8 3.21e-38 Probable inactive peptidyl-prolyl cis-trans isomerase-like 6 (PPIase) (Cyclophilin-like protein PPIL6) Mus musculus (Mouse) protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413] GO:0000413; GO:0003755; GO:0005737; GO:0006457 43623 XM_029353413.2 14 21 1 7 4 NA NA NA NA NA NA 43624 XM_029357299.2 3172 1796 1646 2961 2994 O94915 0 Protein furry homolog-like (ALL1-fused gene from chromosome 4p12 protein) Homo sapiens (Human) cell morphogenesis [GO:0000902]; neuron projection development [GO:0031175] GO:0000902; GO:0005938; GO:0030427; GO:0031175 43625 XM_029357299.2 3172 1796 1646 2961 2994 O94915 9.15e-126 Protein furry homolog-like (ALL1-fused gene from chromosome 4p12 protein) Homo sapiens (Human) cell morphogenesis [GO:0000902]; neuron projection development [GO:0031175] GO:0000902; GO:0005938; GO:0030427; GO:0031175 43626 XM_029357299.2 3172 1796 1646 2961 2994 O94915 5.06e-27 Protein furry homolog-like (ALL1-fused gene from chromosome 4p12 protein) Homo sapiens (Human) cell morphogenesis [GO:0000902]; neuron projection development [GO:0031175] GO:0000902; GO:0005938; GO:0030427; GO:0031175 43627 XM_044324419.1 74 58 112 332 68 NA NA NA NA NA NA 43628 XM_029324634.2 24 10 18 9 8 NA NA NA NA NA NA 43629 XM_029355395.2 11 1 7 6 10 NA NA NA NA NA NA 43630 XM_044323857.1 336 1 8 331 467 Q91X34 5.44e-74 Bile acid-CoA:amino acid N-acyltransferase (BACAT) (BAT) (EC 2.3.1.65) (Bile acid-CoA thioesterase) (Choloyl-CoA hydrolase) (EC 3.1.2.27) (Glycine N-choloyltransferase) (Long-chain fatty-acyl-CoA hydrolase) (EC 3.1.2.2) Mus musculus (Mouse) acyl-CoA metabolic process [GO:0006637]; animal organ regeneration [GO:0031100]; bile acid biosynthetic process [GO:0006699]; bile acid conjugation [GO:0002152]; bile acid metabolic process [GO:0008206]; fatty acid metabolic process [GO:0006631]; glycine metabolic process [GO:0006544]; liver development [GO:0001889]; taurine metabolic process [GO:0019530] GO:0001889; GO:0002152; GO:0005777; GO:0005829; GO:0006544; GO:0006631; GO:0006637; GO:0006699; GO:0008206; GO:0016290; GO:0016410; GO:0019530; GO:0031100; GO:0033882; GO:0047617; GO:0047963; GO:0052815; GO:0052816; GO:0052817; GO:0102991 43631 XR_006395061.1 1666 873 846 1479 1441 NA NA NA NA NA NA 43632 XM_029324175.2 7520 6084 5213 10438 7151 Q9VCY8 1.28e-110 Adiponectin receptor protein Drosophila melanogaster (Fruit fly) adiponectin-activated signaling pathway [GO:0033211]; fatty acid oxidation [GO:0019395]; female germ-line stem cell population maintenance [GO:0036099]; glucose homeostasis [GO:0042593]; hormone-mediated signaling pathway [GO:0009755]; positive regulation of insulin secretion [GO:0032024]; triglyceride homeostasis [GO:0070328] GO:0005886; GO:0009755; GO:0016020; GO:0016500; GO:0019395; GO:0032024; GO:0033211; GO:0036099; GO:0038023; GO:0042593; GO:0046872; GO:0070328 43633 XM_044318191.1 0 0 12 16 0 B4E2M5 1.68e-25 Ankyrin repeat domain-containing protein 66 Homo sapiens (Human) NA NA 43634 XM_044314027.1 586 196 401 432 697 Q9BWT3 0 Poly(A) polymerase gamma (PAP-gamma) (EC 2.7.7.19) (Neo-poly(A) polymerase) (Neo-PAP) (Polynucleotide adenylyltransferase gamma) (SRP RNA 3'-adenylating enzyme) (Signal recognition particle RNA-adenylating enzyme) (SRP RNA-adenylating enzyme) Homo sapiens (Human) mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631] GO:0003723; GO:0004652; GO:0005524; GO:0005634; GO:0005654; GO:0005829; GO:0006378; GO:0016020; GO:0016604; GO:0043631; GO:0046872 43635 XM_044310592.1 373 146 245 4 36 P49914 2.97e-23 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) (5,10-methenyl-tetrahydrofolate synthetase) (MTHFS) (Methenyl-THF synthetase) Homo sapiens (Human) folic acid catabolic process [GO:0046657]; folic acid metabolic process [GO:0046655]; folic acid-containing compound biosynthetic process [GO:0009396]; formate metabolic process [GO:0015942]; glutamate metabolic process [GO:0006536]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653] GO:0005524; GO:0005542; GO:0005737; GO:0005739; GO:0005759; GO:0005829; GO:0006536; GO:0009396; GO:0015942; GO:0030272; GO:0035999; GO:0046653; GO:0046655; GO:0046657; GO:0046872 43636 XM_044323789.1 216 149 125 289 188 NA NA NA NA NA NA 43637 XM_044322982.1 0 23 0 0 0 NA NA NA NA NA NA 43638 XM_044320004.1 239 240 130 272 256 P97846 6.14e-37 Contactin-associated protein 1 (Caspr) (Caspr1) (Neurexin IV) (Neurexin-4) (Paranodin) (p190) Rattus norvegicus (Rat) axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cytoskeleton organization [GO:0007010]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process [GO:0050905]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuronal action potential propagation [GO:0019227]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; postsynaptic density organization [GO:0097106]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; regulation of synapse maturation [GO:0090128] GO:0002175; GO:0007005; GO:0007010; GO:0007155; GO:0007409; GO:0016020; GO:0017124; GO:0019227; GO:0022010; GO:0022011; GO:0030424; GO:0030913; GO:0031175; GO:0033010; GO:0033270; GO:0042552; GO:0048786; GO:0048812; GO:0050884; GO:0050885; GO:0050905; GO:0071205; GO:0090128; GO:0097106; GO:0098529; GO:0098978; GO:1990227 43639 XM_044313431.1 110 86 339 44 469 NA NA NA NA NA NA 43640 XM_044317914.1 34 75 90 31 164 O55230 2.53e-68 DNA repair protein RAD51 homolog 4 (R51H3) (RAD51 homolog D) (RAD51-like protein 3) Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; chromosome organization [GO:0051276]; double-strand break repair via homologous recombination [GO:0000724]; interstrand cross-link repair [GO:0036297]; reciprocal meiotic recombination [GO:0007131]; regulation of cell cycle [GO:0051726]; strand invasion [GO:0042148]; telomere maintenance [GO:0000723]; telomere maintenance via recombination [GO:0000722] GO:0000400; GO:0000722; GO:0000723; GO:0000724; GO:0000781; GO:0003697; GO:0005524; GO:0005657; GO:0005813; GO:0006974; GO:0007131; GO:0008094; GO:0033063; GO:0036297; GO:0042148; GO:0043015; GO:0051276; GO:0051726; GO:0140664 43641 XR_006395057.1 266 311 293 290 369 NA NA NA NA NA NA 43642 XM_044319229.1 1861 2869 1442 1365 1162 NA NA NA NA NA NA 43643 XM_029348049.2 25 12 7 101 0 NA NA NA NA NA NA 43644 XR_006393246.1 80 124 49 100 119 NA NA NA NA NA NA 43645 XM_044324658.1 0 306 0 0 0 Q63406 4.61e-149 Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2-transforming sequence-like protein) (OST oncogene) Rattus norvegicus (Rat) positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of catalytic activity [GO:0050790]; Rho protein signal transduction [GO:0007266] GO:0005085; GO:0005545; GO:0005737; GO:0005886; GO:0007266; GO:0016020; GO:0019898; GO:0030027; GO:0035025; GO:0035091; GO:0045944; GO:0050790 43646 XR_006396294.1 232 151 131 152 198 NA NA NA NA NA NA 43647 XM_044316215.1 0 0 0 0 105 Q6IPM2 1.4e-31 IQ domain-containing protein E Homo sapiens (Human) limb morphogenesis [GO:0035108] GO:0005929; GO:0035108; GO:0060170 43648 XM_044320073.1 0 27 0 0 0 B8EIZ7 2.7e-148 NA NA NA NA 43649 XM_029333708.2 196 60 48 133 71 NA NA NA NA NA NA 43650 XM_029349246.2 128 223 113 209 194 Q5FW48 1.72e-88 Aspartate dehydrogenase domain-containing protein Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NAD biosynthetic process [GO:0009435] GO:0009435; GO:0033735; GO:0050661 43651 XM_029338813.2 139 513 8 468 280 NA NA NA NA NA NA 43652 XM_029358543.2 758 900 729 778 641 NA NA NA NA NA NA 43653 XM_044322823.1 64 22 39 97 72 NA NA NA NA NA NA 43654 XM_029346019.2 72 61 93 55 145 NA NA NA NA NA NA 43655 XM_029336077.2 2343 1214 1269 1560 1903 Q08E13 3.43e-123 RING finger protein 10 Bos taurus (Bovine) positive regulation of myelination [GO:0031643]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein autoubiquitination [GO:0051865] GO:0000976; GO:0005634; GO:0005737; GO:0031643; GO:0045944; GO:0046872; GO:0051865; GO:0061630 43656 XM_029323879.2 120 47 0 120 7 F4JTS8 6.71e-134 Protein NO VEIN (Protein EMBRYO DEFECTIVE 2597) Arabidopsis thaliana (Mouse-ear cress) auxin polar transport [GO:0009926]; cell fate specification [GO:0001708]; embryo development ending in seed dormancy [GO:0009793]; leaf vascular tissue pattern formation [GO:0010305]; root development [GO:0048364]; stem cell population maintenance [GO:0019827] GO:0001708; GO:0005634; GO:0009793; GO:0009926; GO:0010305; GO:0019827; GO:0048364 43657 XM_029339654.2 945 405 264 386 539 Q2HJ98 6.86e-81 Acylpyruvase FAHD1, mitochondrial (EC 3.7.1.5) (Fumarylacetoacetate hydrolase domain-containing protein 1) (Oxaloacetate decarboxylase) (OAA decarboxylase) (EC 4.1.1.112) Bos taurus (Bovine) pyruvate metabolic process [GO:0006090] GO:0005654; GO:0005739; GO:0005829; GO:0006090; GO:0008948; GO:0018773; GO:0034545; GO:0046872; GO:0047621 43658 XM_044327841.1 47 18 32 38 67 NA NA NA NA NA NA 43659 XM_029336142.2 634 648 255 808 911 L7YAI7 1.95e-81 Beta-1,4-glucuronyltransferase 1 (EC 2.4.1.-) (I-beta-1,3-N-acetylglucosaminyltransferase) (N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase) (Poly-N-acetyllactosamine extension enzyme) (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1) Danio rerio (Zebrafish) (Brachydanio rerio) protein glycosylation [GO:0006486]; protein O-linked mannosylation [GO:0035269] GO:0000139; GO:0005794; GO:0006486; GO:0015020; GO:0035269; GO:0046872 43660 XM_044322039.1 4 0 0 10 11 P31696 7.41e-44 Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment (C90); Agrin C-terminal 22 kDa fragment (C22)] Gallus gallus (Chicken) actin cytoskeleton reorganization [GO:0031532]; brain development [GO:0007420]; cell differentiation [GO:0030154]; filopodium assembly [GO:0046847]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; negative regulation of neuron projection development [GO:0010977]; nervous system development [GO:0007399]; neuromuscular junction development [GO:0007528]; neuron cell-cell adhesion [GO:0007158]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of synaptic assembly at neuromuscular junction [GO:0045887]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor clustering [GO:0043113]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340] GO:0002162; GO:0005509; GO:0005539; GO:0005576; GO:0005604; GO:0005615; GO:0005886; GO:0007158; GO:0007213; GO:0007399; GO:0007420; GO:0007528; GO:0008201; GO:0010977; GO:0030154; GO:0030297; GO:0030424; GO:0030548; GO:0031012; GO:0031532; GO:0031594; GO:0033691; GO:0035374; GO:0038023; GO:0043113; GO:0043236; GO:0043237; GO:0043395; GO:0043547; GO:0045121; GO:0045178; GO:0045202; GO:0045887; GO:0045944; GO:0046847; GO:0050840; GO:0051491; GO:0071340; GO:0098684; GO:0098965; GO:0098978 43661 XM_044322039.1 4 0 0 10 11 P31696 2.59e-42 Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment (C90); Agrin C-terminal 22 kDa fragment (C22)] Gallus gallus (Chicken) actin cytoskeleton reorganization [GO:0031532]; brain development [GO:0007420]; cell differentiation [GO:0030154]; filopodium assembly [GO:0046847]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; negative regulation of neuron projection development [GO:0010977]; nervous system development [GO:0007399]; neuromuscular junction development [GO:0007528]; neuron cell-cell adhesion [GO:0007158]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of synaptic assembly at neuromuscular junction [GO:0045887]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor clustering [GO:0043113]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340] GO:0002162; GO:0005509; GO:0005539; GO:0005576; GO:0005604; GO:0005615; GO:0005886; GO:0007158; GO:0007213; GO:0007399; GO:0007420; GO:0007528; GO:0008201; GO:0010977; GO:0030154; GO:0030297; GO:0030424; GO:0030548; GO:0031012; GO:0031532; GO:0031594; GO:0033691; GO:0035374; GO:0038023; GO:0043113; GO:0043236; GO:0043237; GO:0043395; GO:0043547; GO:0045121; GO:0045178; GO:0045202; GO:0045887; GO:0045944; GO:0046847; GO:0050840; GO:0051491; GO:0071340; GO:0098684; GO:0098965; GO:0098978 43662 XM_044322039.1 4 0 0 10 11 P31696 1.21e-27 Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment (C90); Agrin C-terminal 22 kDa fragment (C22)] Gallus gallus (Chicken) actin cytoskeleton reorganization [GO:0031532]; brain development [GO:0007420]; cell differentiation [GO:0030154]; filopodium assembly [GO:0046847]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; negative regulation of neuron projection development [GO:0010977]; nervous system development [GO:0007399]; neuromuscular junction development [GO:0007528]; neuron cell-cell adhesion [GO:0007158]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of synaptic assembly at neuromuscular junction [GO:0045887]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor clustering [GO:0043113]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340] GO:0002162; GO:0005509; GO:0005539; GO:0005576; GO:0005604; GO:0005615; GO:0005886; GO:0007158; GO:0007213; GO:0007399; GO:0007420; GO:0007528; GO:0008201; GO:0010977; GO:0030154; GO:0030297; GO:0030424; GO:0030548; GO:0031012; GO:0031532; GO:0031594; GO:0033691; GO:0035374; GO:0038023; GO:0043113; GO:0043236; GO:0043237; GO:0043395; GO:0043547; GO:0045121; GO:0045178; GO:0045202; GO:0045887; GO:0045944; GO:0046847; GO:0050840; GO:0051491; GO:0071340; GO:0098684; GO:0098965; GO:0098978 43663 XM_044322039.1 4 0 0 10 11 P31696 2.95e-25 Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment (C90); Agrin C-terminal 22 kDa fragment (C22)] Gallus gallus (Chicken) actin cytoskeleton reorganization [GO:0031532]; brain development [GO:0007420]; cell differentiation [GO:0030154]; filopodium assembly [GO:0046847]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; negative regulation of neuron projection development [GO:0010977]; nervous system development [GO:0007399]; neuromuscular junction development [GO:0007528]; neuron cell-cell adhesion [GO:0007158]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of synaptic assembly at neuromuscular junction [GO:0045887]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor clustering [GO:0043113]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340] GO:0002162; GO:0005509; GO:0005539; GO:0005576; GO:0005604; GO:0005615; GO:0005886; GO:0007158; GO:0007213; GO:0007399; GO:0007420; GO:0007528; GO:0008201; GO:0010977; GO:0030154; GO:0030297; GO:0030424; GO:0030548; GO:0031012; GO:0031532; GO:0031594; GO:0033691; GO:0035374; GO:0038023; GO:0043113; GO:0043236; GO:0043237; GO:0043395; GO:0043547; GO:0045121; GO:0045178; GO:0045202; GO:0045887; GO:0045944; GO:0046847; GO:0050840; GO:0051491; GO:0071340; GO:0098684; GO:0098965; GO:0098978 43664 XM_044322039.1 4 0 0 10 11 P31696 9.96e-22 Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment (C90); Agrin C-terminal 22 kDa fragment (C22)] Gallus gallus (Chicken) actin cytoskeleton reorganization [GO:0031532]; brain development [GO:0007420]; cell differentiation [GO:0030154]; filopodium assembly [GO:0046847]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; negative regulation of neuron projection development [GO:0010977]; nervous system development [GO:0007399]; neuromuscular junction development [GO:0007528]; neuron cell-cell adhesion [GO:0007158]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of synaptic assembly at neuromuscular junction [GO:0045887]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor clustering [GO:0043113]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340] GO:0002162; GO:0005509; GO:0005539; GO:0005576; GO:0005604; GO:0005615; GO:0005886; GO:0007158; GO:0007213; GO:0007399; GO:0007420; GO:0007528; GO:0008201; GO:0010977; GO:0030154; GO:0030297; GO:0030424; GO:0030548; GO:0031012; GO:0031532; GO:0031594; GO:0033691; GO:0035374; GO:0038023; GO:0043113; GO:0043236; GO:0043237; GO:0043395; GO:0043547; GO:0045121; GO:0045178; GO:0045202; GO:0045887; GO:0045944; GO:0046847; GO:0050840; GO:0051491; GO:0071340; GO:0098684; GO:0098965; GO:0098978 43665 XR_006397811.1 45 241 122 204 552 NA NA NA NA NA NA 43666 XM_044318993.1 258 98 32 313 171 NA NA NA NA NA NA 43667 XM_029352637.2 476 321 0 0 371 NA NA NA NA NA NA 43668 XM_029343722.2 85 3 64 20 509 NA NA NA NA NA NA 43669 XM_044307894.1 147 0 47 98 9 NA NA NA NA NA NA 43670 XM_044320619.1 0 6 0 0 34 NA NA NA NA NA NA 43671 XR_003828563.2 1790 1002 549 815 499 NA NA NA NA NA NA 43672 XM_029332372.2 228 105 0 40 81 Q6UB98 3.13e-34 Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein) Homo sapiens (Human) NA GO:0005654; GO:0005829 43673 XM_029350768.2 67 9 154 0 195 P14381 7.87e-70 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 43674 XM_029331055.2 2577 1323 975 2084 1439 Q95209 0 Sortilin-related receptor (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (SorLA-1) (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) Oryctolagus cuniculus (Rabbit) adaptive thermogenesis [GO:1990845]; diet induced thermogenesis [GO:0002024]; endocytosis [GO:0006897]; insulin receptor recycling [GO:0038020]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of triglyceride catabolic process [GO:0010897]; positive regulation of adipose tissue development [GO:1904179]; positive regulation of insulin receptor signaling pathway [GO:0046628]; protein targeting [GO:0006605]; regulation of smooth muscle cell migration [GO:0014910] GO:0000139; GO:0002024; GO:0005615; GO:0005768; GO:0005769; GO:0005771; GO:0005783; GO:0005789; GO:0005794; GO:0005886; GO:0006605; GO:0006897; GO:0010897; GO:0014910; GO:0016020; GO:0030514; GO:0030658; GO:0031901; GO:0032585; GO:0038020; GO:0046628; GO:0055038; GO:1904179; GO:1990845 43675 XR_006395973.1 268 506 184 468 800 NA NA NA NA NA NA 43676 XM_044318914.1 0 16 7 9 45 NA NA NA NA NA NA 43677 XM_029358354.2 376 352 156 241 282 NA NA NA NA NA NA 43678 XM_029351648.2 118 166 18 206 342 Q9UJT9 1.54e-99 F-box/LRR-repeat protein 7 (F-box and leucine-rich repeat protein 7) (F-box protein FBL6/FBL7) Homo sapiens (Human) cell division [GO:0051301]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic cell cycle [GO:0000278]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000086; GO:0000151; GO:0000209; GO:0000278; GO:0005813; GO:0005829; GO:0006511; GO:0016567; GO:0019005; GO:0031146; GO:0051301 43679 XM_044311285.1 20 7 34 10 18 NA NA NA NA NA NA 43680 XM_044316460.1 13 3 8 48 187 Q9VBW3 2.21e-57 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 43681 XM_029336561.2 28 0 0 18 71 Q29496 6.98e-96 Cytochrome P450 3A24 (EC 1.14.14.1) (CYPIIIA24) Ovis aries (Sheep) NA GO:0004497; GO:0005506; GO:0005789; GO:0020037; GO:0070330 43682 XM_029327092.2 8681 7400 3866 6875 5722 Q7M767 7.3e-47 Ubiquitin-conjugating enzyme E2 variant 2 (Ubiquitin-conjugating enzyme variant MMS2) Rattus norvegicus (Rat) DNA double-strand break processing [GO:0000729]; error-free postreplication DNA repair [GO:0042275]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of DNA repair [GO:0045739]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of neuron projection development [GO:0010976]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of synapse assembly [GO:0051965]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209] GO:0000209; GO:0000729; GO:0005634; GO:0006301; GO:0010976; GO:0031372; GO:0032436; GO:0042275; GO:0043524; GO:0045739; GO:0051965; GO:0070534; GO:1902523; GO:2000781 43683 XM_044321139.1 5 7 6 12 63 Q9U6Y5 1.82e-147 GFP-like fluorescent chromoprotein FP506 (zFP506) Zoanthus sp. (Green polyp) bioluminescence [GO:0008218] GO:0008218 43684 XM_029335444.2 313 317 0 0 193 NA NA NA NA NA NA 43685 XR_006397483.1 62 242 98 39 155 NA NA NA NA NA NA 43686 XR_006397943.1 3966 1709 1544 2597 2076 P18293 0 Atrial natriuretic peptide receptor 1 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type A) (ANP-A) (ANPR-A) (NPR-A) (Guanylate cyclase A) (GC-A) Mus musculus (Mouse) blood vessel diameter maintenance [GO:0097746]; cell surface receptor signaling pathway [GO:0007166]; cGMP biosynthetic process [GO:0006182]; cGMP-mediated signaling [GO:0019934]; dopamine metabolic process [GO:0042417]; intracellular signal transduction [GO:0035556]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of cGMP-mediated signaling [GO:0010753]; protein phosphorylation [GO:0006468]; receptor guanylyl cyclase signaling pathway [GO:0007168]; regulation of blood pressure [GO:0008217]; signal transduction [GO:0007165] GO:0001653; GO:0004383; GO:0004672; GO:0005524; GO:0005525; GO:0005886; GO:0006182; GO:0006468; GO:0007165; GO:0007166; GO:0007168; GO:0008217; GO:0010753; GO:0016941; GO:0017046; GO:0019934; GO:0035556; GO:0042417; GO:0042562; GO:0043235; GO:0048662; GO:0097746; GO:1990620 43687 XR_006397943.1 3966 1709 1544 2597 2076 P18293 0 Atrial natriuretic peptide receptor 1 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type A) (ANP-A) (ANPR-A) (NPR-A) (Guanylate cyclase A) (GC-A) Mus musculus (Mouse) blood vessel diameter maintenance [GO:0097746]; cell surface receptor signaling pathway [GO:0007166]; cGMP biosynthetic process [GO:0006182]; cGMP-mediated signaling [GO:0019934]; dopamine metabolic process [GO:0042417]; intracellular signal transduction [GO:0035556]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of cGMP-mediated signaling [GO:0010753]; protein phosphorylation [GO:0006468]; receptor guanylyl cyclase signaling pathway [GO:0007168]; regulation of blood pressure [GO:0008217]; signal transduction [GO:0007165] GO:0001653; GO:0004383; GO:0004672; GO:0005524; GO:0005525; GO:0005886; GO:0006182; GO:0006468; GO:0007165; GO:0007166; GO:0007168; GO:0008217; GO:0010753; GO:0016941; GO:0017046; GO:0019934; GO:0035556; GO:0042417; GO:0042562; GO:0043235; GO:0048662; GO:0097746; GO:1990620 43688 XM_044310233.1 9 0 11 16 0 NA NA NA NA NA NA 43689 XM_029349735.2 4500 4990 4131 4798 5640 C3YFB4 1.8e-67 Anamorsin homolog (Fe-S cluster assembly protein DRE2 homolog) Branchiostoma floridae (Florida lancelet) (Amphioxus) iron-sulfur cluster assembly [GO:0016226] GO:0005737; GO:0005758; GO:0009055; GO:0016226; GO:0046872; GO:0051537; GO:0051539 43690 XM_044326590.1 710 0 0 255 492 Q91285 8.54e-49 Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (PFR1) Pleurodeles waltl (Iberian ribbed newt) positive regulation of cell population proliferation [GO:0008284] GO:0005007; GO:0005524; GO:0005634; GO:0005829; GO:0005886; GO:0008284; GO:0031410 43691 XM_044326585.1 45 11 20 32 33 Q80TR8 0 DDB1- and CUL4-associated factor 1 (Serine/threonine-protein kinase VPRBP) (EC 2.7.11.1) Mus musculus (Mouse) B cell differentiation [GO:0030183]; cell competition in a multicellular organism [GO:0035212]; chromatin organization [GO:0006325]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phosphorylation [GO:0016310]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; V(D)J recombination [GO:0033151] GO:0000122; GO:0001650; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0006325; GO:0008180; GO:0016310; GO:0016567; GO:0030183; GO:0030331; GO:0033151; GO:0035212; GO:0043687; GO:0080008; GO:0106310; GO:1990244 43692 XM_044326585.1 45 11 20 32 33 Q80TR8 2.96e-98 DDB1- and CUL4-associated factor 1 (Serine/threonine-protein kinase VPRBP) (EC 2.7.11.1) Mus musculus (Mouse) B cell differentiation [GO:0030183]; cell competition in a multicellular organism [GO:0035212]; chromatin organization [GO:0006325]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phosphorylation [GO:0016310]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; V(D)J recombination [GO:0033151] GO:0000122; GO:0001650; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0006325; GO:0008180; GO:0016310; GO:0016567; GO:0030183; GO:0030331; GO:0033151; GO:0035212; GO:0043687; GO:0080008; GO:0106310; GO:1990244 43693 XM_044309522.1 3 0 0 12 37 NA NA NA NA NA NA 43694 XM_029331926.2 0 0 90 0 0 Q9BQS2 8.26e-35 Synaptotagmin-15 (Chr10Syt) (Synaptotagmin XV) (SytXV) Homo sapiens (Human) calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; vesicle-mediated transport [GO:0016192] GO:0000149; GO:0001786; GO:0005509; GO:0005544; GO:0005886; GO:0014059; GO:0016192; GO:0017156; GO:0017158; GO:0030276; GO:0070382; GO:0071277 43695 XM_029356143.2 0 0 51 0 0 NA NA NA NA NA NA 43696 XM_029353055.2 140 65 72 55 70 Q6PC60 1.12e-58 Histone H2B 3 Danio rerio (Zebrafish) (Brachydanio rerio) nucleosome assembly [GO:0006334] GO:0000785; GO:0000786; GO:0003677; GO:0005634; GO:0006334; GO:0030527; GO:0046982 43697 XM_044328748.1 7 0 0 0 6 NA NA NA NA NA NA 43698 XM_044321086.1 59 46 0 58 240 Q9NZJ4 0 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 43699 XR_006393242.1 64 85 67 13 0 NA NA NA NA NA NA 43700 XM_029349344.2 0 0 33 16 0 F1QZ15 5.33e-41 EKC/KEOPS complex subunit TPRKB (PRPK-binding protein) (TP53RK-binding protein) Danio rerio (Zebrafish) (Brachydanio rerio) tRNA threonylcarbamoyladenosine modification [GO:0002949] GO:0000408; GO:0002949; GO:0005634; GO:0005737; GO:0005829 43701 XM_029346280.2 1480 876 874 1581 1271 P07098 2.79e-128 Gastric triacylglycerol lipase (GL) (Gastric lipase) (EC 3.1.1.3) Homo sapiens (Human) lipid catabolic process [GO:0016042]; malate metabolic process [GO:0006108]; triglyceride metabolic process [GO:0006641] GO:0004806; GO:0005576; GO:0005739; GO:0006108; GO:0006641; GO:0008289; GO:0016042; GO:0016615; GO:0043231 43702 XM_044308244.1 1021 903 652 792 1572 NA NA NA NA NA NA 43703 XR_006393126.1 2 364 179 244 777 NA NA NA NA NA NA 43704 XM_029355598.2 211 218 73 29 29 O15439 0 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 43705 XM_029340331.2 1223 878 749 1142 965 O94885 1.7e-24 SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat-containing protein) Homo sapiens (Human) positive regulation of angiogenesis [GO:0045766]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of p38MAPK cascade [GO:1900745]; protein polyubiquitination [GO:0000209]; regulation of epithelial cell migration [GO:0010632]; regulation of protein autoubiquitination [GO:1902498]; regulation of protein K63-linked ubiquitination [GO:1900044] GO:0000209; GO:0001965; GO:0005737; GO:0008022; GO:0010595; GO:0010632; GO:0019901; GO:0031435; GO:0031666; GO:0032991; GO:0043507; GO:0045766; GO:0060090; GO:1900044; GO:1900745; GO:1901224; GO:1902498 43706 XR_006397972.1 164 35 244 93 532 NA NA NA NA NA NA 43707 XR_006393704.1 784 75 15 114 224 NA NA NA NA NA NA 43708 XM_044315535.1 0 5 0 64 51 NA NA NA NA NA NA 43709 XR_006396010.1 0 0 0 0 60 NA NA NA NA NA NA 43710 XM_029357925.2 77 119 26 107 75 Q1L8X9 5.26e-116 Vesicular glutamate transporter 3 (VGluT3) (Solute carrier family 17 member 8) Danio rerio (Zebrafish) (Brachydanio rerio) anion transport [GO:0006820]; equilibrioception [GO:0050957]; L-glutamate import [GO:0051938]; L-glutamate transmembrane transport [GO:0015813]; neurotransmitter loading into synaptic vesicle [GO:0098700]; phosphate ion homeostasis [GO:0055062]; positive regulation of glutamate uptake involved in transmission of nerve impulse [GO:0051951]; regulation of acetylcholine uptake [GO:0051631]; regulation of synapse structure or activity [GO:0050803]; sodium-dependent phosphate transport [GO:0044341]; synaptic transmission, glutamatergic [GO:0035249]; vestibular reflex [GO:0060005] GO:0005254; GO:0005313; GO:0005326; GO:0005436; GO:0005886; GO:0006820; GO:0015813; GO:0016020; GO:0022857; GO:0030672; GO:0034707; GO:0035249; GO:0043005; GO:0044341; GO:0050803; GO:0050957; GO:0051631; GO:0051938; GO:0051951; GO:0055062; GO:0060005; GO:0060076; GO:0098700; GO:0140788 43711 XM_044311201.1 0 4 4 146 6 NA NA NA NA NA NA 43712 XM_029340153.2 591 1 71 273 764 P97292 3.41e-21 Histamine H2 receptor (H2R) (HH2R) (Gastric receptor I) Mus musculus (Mouse) chemical synaptic transmission [GO:0007268]; digestive tract development [GO:0048565]; epithelial cell morphogenesis [GO:0003382]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; gastric acid secretion [GO:0001696]; gastrin-induced gastric acid secretion [GO:0001698]; gland development [GO:0048732]; histamine-induced gastric acid secretion [GO:0001697]; memory [GO:0007613]; negative regulation of arachidonic acid secretion [GO:1900139]; positive regulation of vasoconstriction [GO:0045907]; regulation of synaptic plasticity [GO:0048167]; toxin transport [GO:1901998]; visual learning [GO:0008542] GO:0001696; GO:0001697; GO:0001698; GO:0003382; GO:0004969; GO:0004993; GO:0005886; GO:0007187; GO:0007268; GO:0007613; GO:0008542; GO:0016020; GO:0030425; GO:0030594; GO:0045202; GO:0045907; GO:0048167; GO:0048565; GO:0048732; GO:1900139; GO:1901363; GO:1901998 43713 XR_003824798.2 12 0 29 12 17 NA NA NA NA NA NA 43714 XM_044327214.1 14 0 6 0 28 NA NA NA NA NA NA 43715 XM_044320403.1 682 525 1044 1266 952 NA NA NA NA NA NA 43716 XM_044308411.1 72 83 0 0 0 NA NA NA NA NA NA 43717 XM_044325945.1 12 4 9 5 27 NA NA NA NA NA NA 43718 XM_044315141.1 27 0 8 8 1 NA NA NA NA NA NA 43719 XM_029345028.2 1055 540 347 1180 984 NA NA NA NA NA NA 43720 XR_006394367.1 0 1 0 10 70 NA NA NA NA NA NA 43721 XM_029338896.2 165 18 186 239 203 Q9NUD9 2.07e-70 GPI mannosyltransferase 2 (EC 2.4.1.-) (GPI mannosyltransferase II) (GPI-MT-II) (Phosphatidylinositol-glycan biosynthesis class V protein) (PIG-V) Homo sapiens (Human) GPI anchor biosynthetic process [GO:0006506]; preassembly of GPI anchor in ER membrane [GO:0016254] GO:0000009; GO:0000030; GO:0004376; GO:0005789; GO:0006506; GO:0016020; GO:0016254; GO:0031501 43722 XM_029344432.2 657 1310 439 813 751 NA NA NA NA NA NA 43723 XM_044322779.1 2 20 11 7 13 NA NA NA NA NA NA 43724 XR_006395813.1 689 501 371 438 373 NA NA NA NA NA NA 43725 XM_044318995.1 148 59 87 84 177 Q17GZ9 6.84e-145 Actin-related protein 5 Aedes aegypti (Yellowfever mosquito) (Culex aegypti) chromatin remodeling [GO:0006338]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006281; GO:0006310; GO:0006338; GO:0006355 43726 XM_029338047.2 2376 2514 1478 2511 1671 P28039 2.36e-153 Acyloxyacyl hydrolase (EC 3.1.1.77) [Cleaved into: Acyloxyacyl hydrolase small subunit; Acyloxyacyl hydrolase large subunit] Homo sapiens (Human) fatty acid metabolic process [GO:0006631]; lipopolysaccharide catabolic process [GO:0009104]; negative regulation of inflammatory response [GO:0050728] GO:0005509; GO:0005576; GO:0006631; GO:0009104; GO:0031410; GO:0043231; GO:0050528; GO:0050728 43727 XM_044308626.1 9 0 0 26 87 NA NA NA NA NA NA 43728 XM_044329256.1 0 0 0 0 2697 NA NA NA NA NA NA 43729 XM_029356156.2 23 0 0 217 43 Q7ZWG6 1.93e-59 Proton-coupled folate transporter (Solute carrier family 46 member 1) Danio rerio (Zebrafish) (Brachydanio rerio) transmembrane transport [GO:0055085] GO:0005542; GO:0005768; GO:0005886; GO:0010008; GO:0015293; GO:0015350; GO:0016020; GO:0016323; GO:0016324; GO:0022857; GO:0055085 43730 XM_044318113.1 34 18 12 11 35 NA NA NA NA NA NA 43731 XM_044324786.1 0 563 564 613 809 NA NA NA NA NA NA 43732 XM_044319132.1 0 0 0 99 0 NA NA NA NA NA NA 43733 XM_044310817.1 0 14 10 0 10 NA NA NA NA NA NA 43734 XM_044307855.1 225 0 71 291 513 NA NA NA NA NA NA 43735 XR_006395358.1 998 663 753 822 1009 Q13523 1.43e-178 Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 kinase) (PRP4 pre-mRNA-processing factor 4 homolog) Homo sapiens (Human) mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; protein phosphorylation [GO:0006468]; RNA splicing [GO:0008380] GO:0000398; GO:0003723; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005694; GO:0006468; GO:0008380; GO:0016607; GO:0045292; GO:0071013; GO:0106310 43736 XM_029330589.2 1141 773 271 1518 1120 O95395 8.9e-62 Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 (EC 2.4.1.102) (EC 2.4.1.148) (EC 2.4.1.150) (C2GnT-mucin type) (C2GnT-M) (hC2GnT-M) (Core 2/core 4 beta-1,6-N-acetylglucosaminyltransferase) (C2/4GnT) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; intestinal absorption [GO:0050892]; kidney morphogenesis [GO:0060993]; O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493]; tissue morphogenesis [GO:0048729] GO:0000139; GO:0003829; GO:0005975; GO:0006493; GO:0008109; GO:0008375; GO:0016020; GO:0016266; GO:0048729; GO:0050892; GO:0060993; GO:0070062; GO:0106325; GO:0106326 43737 XR_006394023.1 4 1 28 7 0 NA NA NA NA NA NA 43738 XM_044308760.1 2612 1430 1105 2565 2275 Q99MD6 0 Thioredoxin reductase 3 (EC 1.8.1.9) (Thioredoxin and glutathione reductase) (Thioredoxin reductase TR2) Mus musculus (Mouse) blastocyst formation [GO:0001825]; cell differentiation [GO:0030154]; cell redox homeostasis [GO:0045454]; glutathione metabolic process [GO:0006749]; spermatogenesis [GO:0007283] GO:0001825; GO:0004791; GO:0005654; GO:0005739; GO:0005783; GO:0005829; GO:0006749; GO:0007283; GO:0030154; GO:0045454; GO:0050660 43739 XM_044317805.1 44 45 19 52 113 Q5R868 1.02e-34 Post-GPI attachment to proteins factor 4 (Post-GPI attachment to proteins GalNAc transferase 4) (Transmembrane protein 246) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) GPI anchor biosynthetic process [GO:0006506] GO:0000139; GO:0006506; GO:0016757 43740 XM_044314051.1 2760 2211 1953 1795 1225 Q6AZN8 1.37e-107 Zinc transporter 6-A (ZnT-6-A) (Solute carrier family 30 member 6-A) Xenopus laevis (African clawed frog) zinc ion import into Golgi lumen [GO:1904257] GO:0008324; GO:0032588; GO:1904257 43741 XM_044312752.1 599 278 458 536 721 Q11011 0 Puromycin-sensitive aminopeptidase (PSA) (EC 3.4.11.14) (Cytosol alanyl aminopeptidase) (AAP-S) Mus musculus (Mouse) cellular response to hypoxia [GO:0071456]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508] GO:0004177; GO:0005634; GO:0005737; GO:0005829; GO:0006508; GO:0008270; GO:0042277; GO:0043171; GO:0070006; GO:0071456 43742 XR_003827620.2 6 10 3 8 20 NA NA NA NA NA NA 43743 XM_029327017.2 22 0 0 0 0 Q8R4K8 0 Pappalysin-1 (EC 3.4.24.79) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase) (Pregnancy-associated plasma protein A) (PAPP-A) Mus musculus (Mouse) cell surface receptor signaling pathway [GO:0007166]; female pregnancy [GO:0007565]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to dexamethasone [GO:0071548]; response to follicle-stimulating hormone [GO:0032354] GO:0004175; GO:0004222; GO:0005576; GO:0005615; GO:0006508; GO:0007166; GO:0007565; GO:0008237; GO:0030163; GO:0032354; GO:0046872; GO:0071548 43744 XM_044324522.1 369 370 201 378 217 Q8BG19 0 Protein O-mannosyl-transferase TMTC4 (EC 2.4.1.109) (Transmembrane and TPR repeat-containing protein 4) Mus musculus (Mouse) endoplasmic reticulum unfolded protein response [GO:0030968]; outer hair cell apoptotic process [GO:1905584]; positive regulation of endoplasmic reticulum calcium ion concentration [GO:0032470]; protein O-linked mannosylation [GO:0035269]; sensory perception of sound [GO:0007605] GO:0000030; GO:0004169; GO:0005783; GO:0007605; GO:0016020; GO:0030968; GO:0032470; GO:0035269; GO:0051117; GO:1905584 43745 XM_029338161.2 450 202 414 269 431 NA NA NA NA NA NA 43746 XR_006393132.1 20806 44266 30377 14344 21817 NA NA NA NA NA NA 43747 XM_029352636.2 10 28 6 77 100 NA NA NA NA NA NA 43748 XM_029333353.2 1 7 0 5 17 P04323 1.94e-52 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 43749 XM_029354901.2 166 60 52 64 126 Q5PP32 3.43e-34 WAT1-related protein At3g45870 Arabidopsis thaliana (Mouse-ear cress) NA GO:0005886; GO:0022857 43750 XM_044320123.1 10 33 0 49 61 Q9D2J7 0 Ankyrin repeat and EF-hand domain-containing protein 1 (Ankyrin repeat domain-containing protein 5) Mus musculus (Mouse) NA NA 43751 XM_029345623.2 47 5 12 13 13 NA NA NA NA NA NA 43752 XM_044329308.1 0 0 26 16 0 Q8AWD2 2.38e-132 Adenylyltransferase and sulfurtransferase MOCS3 (Molybdenum cofactor synthesis protein 3) [Includes: Molybdopterin-synthase adenylyltransferase (EC 2.7.7.80) (Adenylyltransferase MOCS3) (Sulfur carrier protein MOCS2A adenylyltransferase); Molybdopterin-synthase sulfurtransferase (EC 2.8.1.11) (Sulfur carrier protein MOCS2A sulfurtransferase) (Sulfurtransferase MOCS3)] Danio rerio (Zebrafish) (Brachydanio rerio) Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; protein urmylation [GO:0032447]; tRNA thio-modification [GO:0034227]; tRNA wobble position uridine thiolation [GO:0002143]; tRNA wobble uridine modification [GO:0002098] GO:0002098; GO:0002143; GO:0004792; GO:0005524; GO:0005737; GO:0005829; GO:0006777; GO:0016779; GO:0016783; GO:0032447; GO:0034227; GO:0042292; GO:0046872; GO:0061604; GO:0061605 43753 XM_029336362.2 4 0 11 4 11 NA NA NA NA NA NA 43754 XM_044310180.1 16 36 15 23 20 Q6IR34 7.94e-21 G-protein-signaling modulator 1 (Activator of G-protein signaling 3) Mus musculus (Mouse) cell differentiation [GO:0030154]; establishment of mitotic spindle orientation [GO:0000132]; negative regulation of GTPase activity [GO:0034260]; negative regulation of guanyl-nucleotide exchange factor activity [GO:1905098]; nervous system development [GO:0007399]; positive regulation of macroautophagy [GO:0016239]; regulation of G protein-coupled receptor signaling pathway [GO:0008277] GO:0000132; GO:0000139; GO:0001965; GO:0005092; GO:0005654; GO:0005789; GO:0005829; GO:0005886; GO:0005938; GO:0007399; GO:0008277; GO:0016239; GO:0030154; GO:0032991; GO:0034260; GO:1905098 43755 XM_044316789.1 486 0 230 114 0 Q61824 2.45e-129 Disintegrin and metalloproteinase domain-containing protein 12 (ADAM 12) (EC 3.4.24.-) (Meltrin-alpha) Mus musculus (Mouse) cell adhesion [GO:0007155]; positive regulation of angiogenesis [GO:0045766]; proteolysis [GO:0006508] GO:0004222; GO:0005654; GO:0005886; GO:0006508; GO:0007155; GO:0017124; GO:0045766; GO:0046872 43756 XM_044310132.1 21 18 27 13 0 Q3UQ28 1.33e-32 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 43757 XM_044310132.1 21 18 27 13 0 Q3UQ28 4.86e-31 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 43758 XM_044318449.1 20 43 64 0 24 NA NA NA NA NA NA 43759 XM_029323746.2 37 78 42 84 108 A8WGS4 8.17e-24 TLC domain-containing protein 2 Danio rerio (Zebrafish) (Brachydanio rerio) lipid homeostasis [GO:0055088]; membrane assembly [GO:0071709]; phospholipid homeostasis [GO:0055091]; plasma membrane organization [GO:0007009]; regulation of membrane lipid distribution [GO:0097035] GO:0005886; GO:0007009; GO:0055088; GO:0055091; GO:0071709; GO:0097035 43760 XR_006391625.1 457 353 379 305 260 NA NA NA NA NA NA 43761 XM_044317250.1 1099 1511 821 1221 1502 NA NA NA NA NA NA 43762 XM_044308083.1 36 7 31 91 16 NA NA NA NA NA NA 43763 XM_029329296.2 4963 4869 2862 4260 4223 P63326 1.58e-57 40S ribosomal protein S10 Rattus norvegicus (Rat) ribosomal small subunit assembly [GO:0000028] GO:0000028; GO:0000049; GO:0003723; GO:0003735; GO:0005730; GO:0022626; GO:0022627; GO:0045202 43764 XM_044313488.1 0 75 53 64 0 NA NA NA NA NA NA 43765 XM_029348141.2 25 0 24 0 0 P49338 1.93e-114 Protein Wnt-4 (XWnt-4) Xenopus laevis (African clawed frog) embryonic pattern specification [GO:0009880]; glomus development [GO:0072013]; nephrostome development [GO:0039018]; pronephric nephron tubule development [GO:0039020]; Wnt signaling pathway [GO:0016055] GO:0005102; GO:0005576; GO:0009880; GO:0016055; GO:0039018; GO:0039020; GO:0072013 43766 XM_029339308.2 11197 7647 2504 5771 4121 O46160 6.46e-44 60S ribosomal protein L14 Lumbricus rubellus (Humus earthworm) translation [GO:0006412] GO:0003723; GO:0003735; GO:0005840; GO:0006412; GO:1990904 43767 XM_044308555.1 66 48 0 0 0 Q5U378 1.35e-94 Tubulin-specific chaperone E (Tubulin-folding cofactor E) Danio rerio (Zebrafish) (Brachydanio rerio) microtubule cytoskeleton organization [GO:0000226]; post-chaperonin tubulin folding pathway [GO:0007023]; tubulin complex assembly [GO:0007021] GO:0000226; GO:0005737; GO:0005856; GO:0007021; GO:0007023; GO:0043014 43768 XM_029351799.2 789 844 566 1056 809 Q9WTS8 2.18e-55 Ficolin-1 (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin-alpha) (M-ficolin) Rattus norvegicus (Rat) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to virus [GO:0051607]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of RNA biosynthetic process [GO:1902679]; negative regulation of viral entry into host cell [GO:0046597]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of opsonization [GO:1903028]; proteolysis [GO:0006508]; recognition of apoptotic cell [GO:0043654] GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005581; GO:0005615; GO:0006508; GO:0006956; GO:0007186; GO:0030246; GO:0031232; GO:0032757; GO:0038187; GO:0043654; GO:0046597; GO:0046872; GO:0051607; GO:0062023; GO:0097367; GO:1902679; GO:1903028; GO:1905370 43769 XR_003826698.2 36 14 18 23 48 NA NA NA NA NA NA 43770 XR_003826166.2 2427 4537 2183 2466 1880 NA NA NA NA NA NA 43771 XR_006395151.1 352 373 414 660 488 NA NA NA NA NA NA 43772 XM_044309737.1 12 6 0 12 5 NA NA NA NA NA NA 43773 XM_044319082.1 0 118 235 147 0 NA NA NA NA NA NA 43774 XM_029332950.2 358 627 271 563 621 NA NA NA NA NA NA 43775 XM_029339467.2 44 45 25 115 134 B3EWZ3 0 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 43776 XM_044326618.1 6 0 0 0 0 NA NA NA NA NA NA 43777 XM_029348621.2 27 39 82 31 31 NA NA NA NA NA NA 43778 XM_044321876.1 142 29 9 60 94 Q7ZVH1 2.07e-39 Membrane progestin receptor gamma-A (mPR gamma-A) (Progestin and adipoQ receptor family member V-A) Danio rerio (Zebrafish) (Brachydanio rerio) oogenesis [GO:0048477] GO:0005496; GO:0016020; GO:0038023; GO:0048477 43779 XR_003825781.2 3 0 14 5 11 NA NA NA NA NA NA 43780 XM_029323741.2 33 10 30 16 170 Q9NYQ8 1.55e-25 Protocadherin Fat 2 (hFat2) (Cadherin family member 8) (Multiple epidermal growth factor-like domains protein 1) (Multiple EGF-like domains protein 1) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cell-substrate adhesion [GO:0031589]; epithelial cell migration [GO:0010631]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005794; GO:0005886; GO:0005912; GO:0007156; GO:0010631; GO:0031589; GO:0070062; GO:0098609 43781 XM_029329775.2 0 0 0 177 0 P79134 1.03e-72 Annexin A6 (Annexin VI) (Annexin-6) Bos taurus (Bovine) apoptotic signaling pathway [GO:0097190]; biomineral tissue development [GO:0031214]; calcium ion import [GO:0070509]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; growth plate cartilage chondrocyte differentiation [GO:0003418]; mitochondrial calcium ion homeostasis [GO:0051560]; negative regulation of sequestering of calcium ion [GO:0051283]; neural crest cell migration [GO:0001755]; plasma membrane repair [GO:0001778]; regulation of muscle contraction [GO:0006937] GO:0001725; GO:0001755; GO:0001778; GO:0001786; GO:0003418; GO:0005262; GO:0005509; GO:0005525; GO:0005544; GO:0005737; GO:0005886; GO:0005925; GO:0006816; GO:0006937; GO:0008201; GO:0015276; GO:0015485; GO:0016020; GO:0019899; GO:0030061; GO:0031214; GO:0031982; GO:0035374; GO:0038024; GO:0042470; GO:0042584; GO:0048306; GO:0048471; GO:0051015; GO:0051283; GO:0051560; GO:0070509; GO:0070588; GO:0097190 43782 XM_029329775.2 0 0 0 177 0 P79134 2.3e-59 Annexin A6 (Annexin VI) (Annexin-6) Bos taurus (Bovine) apoptotic signaling pathway [GO:0097190]; biomineral tissue development [GO:0031214]; calcium ion import [GO:0070509]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; growth plate cartilage chondrocyte differentiation [GO:0003418]; mitochondrial calcium ion homeostasis [GO:0051560]; negative regulation of sequestering of calcium ion [GO:0051283]; neural crest cell migration [GO:0001755]; plasma membrane repair [GO:0001778]; regulation of muscle contraction [GO:0006937] GO:0001725; GO:0001755; GO:0001778; GO:0001786; GO:0003418; GO:0005262; GO:0005509; GO:0005525; GO:0005544; GO:0005737; GO:0005886; GO:0005925; GO:0006816; GO:0006937; GO:0008201; GO:0015276; GO:0015485; GO:0016020; GO:0019899; GO:0030061; GO:0031214; GO:0031982; GO:0035374; GO:0038024; GO:0042470; GO:0042584; GO:0048306; GO:0048471; GO:0051015; GO:0051283; GO:0051560; GO:0070509; GO:0070588; GO:0097190 43783 XM_029329775.2 0 0 0 177 0 P79134 3.03e-38 Annexin A6 (Annexin VI) (Annexin-6) Bos taurus (Bovine) apoptotic signaling pathway [GO:0097190]; biomineral tissue development [GO:0031214]; calcium ion import [GO:0070509]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; growth plate cartilage chondrocyte differentiation [GO:0003418]; mitochondrial calcium ion homeostasis [GO:0051560]; negative regulation of sequestering of calcium ion [GO:0051283]; neural crest cell migration [GO:0001755]; plasma membrane repair [GO:0001778]; regulation of muscle contraction [GO:0006937] GO:0001725; GO:0001755; GO:0001778; GO:0001786; GO:0003418; GO:0005262; GO:0005509; GO:0005525; GO:0005544; GO:0005737; GO:0005886; GO:0005925; GO:0006816; GO:0006937; GO:0008201; GO:0015276; GO:0015485; GO:0016020; GO:0019899; GO:0030061; GO:0031214; GO:0031982; GO:0035374; GO:0038024; GO:0042470; GO:0042584; GO:0048306; GO:0048471; GO:0051015; GO:0051283; GO:0051560; GO:0070509; GO:0070588; GO:0097190 43784 XM_029329775.2 0 0 0 177 0 P79134 1.78e-34 Annexin A6 (Annexin VI) (Annexin-6) Bos taurus (Bovine) apoptotic signaling pathway [GO:0097190]; biomineral tissue development [GO:0031214]; calcium ion import [GO:0070509]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; growth plate cartilage chondrocyte differentiation [GO:0003418]; mitochondrial calcium ion homeostasis [GO:0051560]; negative regulation of sequestering of calcium ion [GO:0051283]; neural crest cell migration [GO:0001755]; plasma membrane repair [GO:0001778]; regulation of muscle contraction [GO:0006937] GO:0001725; GO:0001755; GO:0001778; GO:0001786; GO:0003418; GO:0005262; GO:0005509; GO:0005525; GO:0005544; GO:0005737; GO:0005886; GO:0005925; GO:0006816; GO:0006937; GO:0008201; GO:0015276; GO:0015485; GO:0016020; GO:0019899; GO:0030061; GO:0031214; GO:0031982; GO:0035374; GO:0038024; GO:0042470; GO:0042584; GO:0048306; GO:0048471; GO:0051015; GO:0051283; GO:0051560; GO:0070509; GO:0070588; GO:0097190 43785 XM_044314142.1 2 0 1 0 83 NA NA NA NA NA NA 43786 XM_029337516.2 196 40 52 72 55 Q8L7C9 4.12e-31 Glutathione S-transferase U20 (AtGSTU20) (EC 2.5.1.18) (FIN219-interacting protein 1) (GST class-tau member 20) Arabidopsis thaliana (Mouse-ear cress) glutathione metabolic process [GO:0006749]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407] GO:0004364; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0006749; GO:0009407; GO:0009507; GO:0009629; GO:0019899; GO:0043295; GO:0048046; GO:2000030 43787 XM_029342766.2 0 31 4 58 0 P17972 6.57e-115 Potassium voltage-gated channel protein Shaw (Shaw2) Drosophila melanogaster (Fruit fly) potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765]; sleep [GO:0030431] GO:0005249; GO:0005251; GO:0005886; GO:0006813; GO:0008076; GO:0016020; GO:0022843; GO:0030424; GO:0030431; GO:0032590; GO:0032809; GO:0034765; GO:0051260; GO:0071805 43788 XR_006397849.1 600 531 316 388 96 NA NA NA NA NA NA 43789 XM_044317558.1 0 9 0 0 6 Q09575 3.95e-21 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 43790 XM_029342248.2 966 505 424 659 355 NA NA NA NA NA NA 43791 XR_006393459.1 80 48 53 106 130 NA NA NA NA NA NA 43792 XM_029331507.2 0 65 0 12 30 NA NA NA NA NA NA 43793 XR_003824680.2 110 56 41 62 58 NA NA NA NA NA NA 43794 XR_006397734.1 25 54 41 61 56 NA NA NA NA NA NA 43795 XM_029341215.2 68 0 23 35 0 Q91175 1.32e-42 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (MAR1) Oryzias latipes (Japanese rice fish) (Japanese killifish) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of vasoconstriction [GO:0045907] GO:0001996; GO:0004930; GO:0004937; GO:0005886; GO:0007200; GO:0007204; GO:0007267; GO:0043410; GO:0045907; GO:0071880 43796 XM_029327227.2 10071 9898 6003 10397 5984 NA NA NA NA NA NA 43797 XM_044314009.1 40 15 9 8 79 NA NA NA NA NA NA 43798 XM_029327245.2 439 271 272 514 703 NA NA NA NA NA NA 43799 XM_044308737.1 647 260 229 340 414 NA NA NA NA NA NA 43800 XM_029341158.2 336 178 91 769 579 NA NA NA NA NA NA 43801 XM_029351578.1 98 0 212 0 182 Q9DCU6 2.52e-51 39S ribosomal protein L4, mitochondrial (L4mt) (MRP-L4) Mus musculus (Mouse) mitochondrial translation [GO:0032543] GO:0003735; GO:0005739; GO:0005743; GO:0005762; GO:0032543 43802 XM_029335012.2 1642 887 1048 1708 2178 Q5RA75 1.7e-95 Protein FAM135A Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA NA 43803 XM_029335012.2 1642 887 1048 1708 2178 Q5RA75 3.76e-74 Protein FAM135A Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA NA 43804 XR_006394853.1 3 1 3 2 30 NA NA NA NA NA NA 43805 XM_044322247.1 574 739 121 449 246 NA NA NA NA NA NA 43806 XM_044323864.1 0 0 0 0 76 Q6NVY1 5.68e-143 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial (EC 3.1.2.4) (3-hydroxyisobutyryl-coenzyme A hydrolase) (HIB-CoA hydrolase) (HIBYL-CoA-H) Homo sapiens (Human) branched-chain amino acid catabolic process [GO:0009083]; valine catabolic process [GO:0006574] GO:0003860; GO:0005739; GO:0005759; GO:0006574; GO:0009083 43807 XM_029353495.2 2775 4240 1843 3283 4140 P24156 6.45e-141 Protein l(2)37Cc Drosophila melanogaster (Fruit fly) cellular response to hypoxia [GO:0071456]; mitochondrion organization [GO:0007005] GO:0005739; GO:0007005; GO:0016020; GO:0071456 43808 XM_029343826.2 55 740 362 536 564 Q90XC2 1.21e-132 Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never in mitosis A-related kinase 8) (NimA-related protein kinase 8) Danio rerio (Zebrafish) (Brachydanio rerio) animal organ morphogenesis [GO:0009887]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; determination of heart left/right asymmetry [GO:0061371]; heart looping [GO:0001947]; pronephros development [GO:0048793]; pronephros formation [GO:0072116]; protein phosphorylation [GO:0006468]; renal tubule development [GO:0061326] GO:0001947; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005929; GO:0006468; GO:0007059; GO:0009887; GO:0046872; GO:0048793; GO:0051301; GO:0061326; GO:0061371; GO:0072116; GO:0106310 43809 XM_029344673.2 704 386 332 416 495 P21868 0 Casein kinase II subunit alpha (CK II) (EC 2.7.11.1) Gallus gallus (Chicken) peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; regulation of cell cycle [GO:0051726]; rhythmic process [GO:0048511]; Wnt signaling pathway [GO:0016055] GO:0004674; GO:0005524; GO:0005634; GO:0005829; GO:0005956; GO:0016055; GO:0018105; GO:0018107; GO:0048511; GO:0051726; GO:0106310 43810 XM_044323256.1 0 11 0 0 90 O73792 8.27e-53 Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1) Danio rerio (Zebrafish) (Brachydanio rerio) angiogenesis [GO:0001525]; blood vessel development [GO:0001568]; endothelial cell-cell adhesion [GO:0071603]; heart development [GO:0007507]; positive regulation of angiogenesis [GO:0045766]; positive regulation of kinase activity [GO:0033674]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculature development [GO:0001944] GO:0001525; GO:0001568; GO:0001944; GO:0004714; GO:0005524; GO:0005886; GO:0007169; GO:0007507; GO:0033674; GO:0043235; GO:0045766; GO:0071603 43811 XR_006394994.1 40 57 1 13 18 NA NA NA NA NA NA 43812 XR_006398172.1 238 75 95 153 124 NA NA NA NA NA NA 43813 XM_044309790.1 17 0 49 0 1 Q3UHC7 2.5e-139 Disabled homolog 2-interacting protein (DAB2-interacting protein) (ASK-interacting protein 1) (DOC-2/DAB-2 interactive protein) Mus musculus (Mouse) angiogenesis [GO:0001525]; cell cycle [GO:0007049]; cell motility involved in cerebral cortex radial glia guided migration [GO:0021814]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; I-kappaB phosphorylation [GO:0007252]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; layer formation in cerebral cortex [GO:0021819]; negative regulation of angiogenesis [GO:0016525]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of G0 to G1 transition [GO:0070317]; negative regulation of GTPase activity [GO:0034260]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of phosphatidylinositol 3-kinase activity [GO:0043553]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of Ras protein signal transduction [GO:0046580]; negative regulation of toll-like receptor 4 signaling pathway [GO:0034144]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; negative regulation of vascular endothelial growth factor signaling pathway [GO:1900747]; neuron projection morphogenesis [GO:0048812]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of dendrite development [GO:1900006]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron migration [GO:2001224]; positive regulation of neuron projection development [GO:0010976]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of protein-containing complex assembly [GO:0031334]; positive regulation of synapse maturation [GO:0090129]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein catabolic process [GO:0030163]; regulation of cell cycle [GO:0051726]; regulation of GTPase activity [GO:0043087]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of p38MAPK cascade [GO:1900744]; regulation of protein-containing complex assembly [GO:0043254]; response to unfolded protein [GO:0006986]; tube formation [GO:0035148]; vascular endothelial growth factor receptor-2 signaling pathway [GO:0036324] GO:0000122; GO:0001525; GO:0001933; GO:0005096; GO:0005123; GO:0005737; GO:0005886; GO:0006954; GO:0006986; GO:0007049; GO:0007252; GO:0008285; GO:0008625; GO:0010596; GO:0010633; GO:0010719; GO:0010976; GO:0014067; GO:0016525; GO:0017124; GO:0019900; GO:0019901; GO:0021814; GO:0021819; GO:0030139; GO:0030163; GO:0030308; GO:0030424; GO:0030425; GO:0030948; GO:0031334; GO:0031434; GO:0031435; GO:0032088; GO:0032266; GO:0032809; GO:0034144; GO:0034260; GO:0035148; GO:0035591; GO:0035924; GO:0036312; GO:0036324; GO:0042059; GO:0042177; GO:0042802; GO:0042803; GO:0043025; GO:0043065; GO:0043087; GO:0043122; GO:0043124; GO:0043184; GO:0043254; GO:0043407; GO:0043410; GO:0043507; GO:0043539; GO:0043548; GO:0043553; GO:0044300; GO:0044301; GO:0044877; GO:0045087; GO:0045732; GO:0045892; GO:0045944; GO:0046330; GO:0046580; GO:0047485; GO:0048147; GO:0048812; GO:0050679; GO:0050680; GO:0051721; GO:0051726; GO:0070059; GO:0070273; GO:0070317; GO:0070373; GO:0071222; GO:0071347; GO:0071356; GO:0071364; GO:0071889; GO:0071901; GO:0071902; GO:0090090; GO:0090129; GO:1900006; GO:1900744; GO:1900747; GO:1901800; GO:1990032; GO:1990597; GO:2001224; GO:2001235 43814 XM_029341130.2 203 564 373 960 514 O15541 1.05e-100 E3 ubiquitin-protein ligase RNF113A (EC 2.3.2.27) (Cwc24 homolog) (RING finger protein 113A) (Zinc finger protein 183) Homo sapiens (Human) DNA repair [GO:0006281]; isopeptide cross-linking via N6-glycyl-L-lysine [GO:0018276]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; protein ubiquitination [GO:0016567]; snoRNA splicing [GO:0034247] GO:0000398; GO:0005634; GO:0005654; GO:0005684; GO:0006281; GO:0016567; GO:0016607; GO:0018276; GO:0034247; GO:0046872; GO:0061630; GO:0070100; GO:0071005 43815 XM_029341771.2 308 60 55 440 347 Q8NDA2 4.35e-28 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 43816 XM_029341771.2 308 60 55 440 347 Q8NDA2 2.67e-25 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 43817 XM_029341771.2 308 60 55 440 347 Q8NDA2 3.37e-22 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 43818 XM_029324539.2 49 32 32 16 85 NA NA NA NA NA NA 43819 XM_029332961.2 9 0 16 8 7 Q9EQD2 1.54e-29 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 43820 XM_044325409.1 117 0 0 0 82 NA NA NA NA NA NA 43821 XM_029331561.2 1082 745 663 1185 892 Q9Z2D1 9.67e-64 Myotubularin-related protein 2 (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64) Mus musculus (Mouse) dendritic spine maintenance [GO:0097062]; dephosphorylation [GO:0016311]; inositol phosphate dephosphorylation [GO:0046855]; myelin assembly [GO:0032288]; myelination [GO:0042552]; negative regulation of endocytosis [GO:0045806]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of myelination [GO:0031642]; negative regulation of receptor catabolic process [GO:2000645]; negative regulation of receptor internalization [GO:0002091]; neuron development [GO:0048666]; phosphatidylinositol dephosphorylation [GO:0046856]; phosphatidylinositol metabolic process [GO:0046488]; positive regulation of early endosome to late endosome transport [GO:2000643]; regulation of phosphatidylinositol dephosphorylation [GO:0060304] GO:0002091; GO:0004438; GO:0005634; GO:0005737; GO:0005774; GO:0005829; GO:0008021; GO:0014069; GO:0016311; GO:0030424; GO:0030425; GO:0031642; GO:0031901; GO:0032288; GO:0042552; GO:0042802; GO:0043197; GO:0043231; GO:0045806; GO:0046488; GO:0046855; GO:0046856; GO:0048471; GO:0048666; GO:0052629; GO:0052866; GO:0060304; GO:0090394; GO:0097060; GO:0097062; GO:2000643; GO:2000645 43822 XM_044321902.1 12 0 0 8 17 Q9DGD1 6.13e-62 Alpha-1,6-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase (EC 2.4.1.201) (N-acetylglucosaminyltransferase VI) (GnT-VI) Gallus gallus (Chicken) protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0046872; GO:0047253 43823 XM_044310472.1 674 545 247 230 471 NA NA NA NA NA NA 43824 XM_029334106.2 0 0 24 0 0 Q8BFQ8 2.13e-63 Glutamine amidotransferase-like class 1 domain-containing protein 1 (Parkinson disease 7 domain-containing protein 1) Mus musculus (Mouse) methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243] GO:0005576; GO:0005737; GO:0019172; GO:0019243 43825 XM_044327664.1 129 8 232 230 164 NA NA NA NA NA NA 43826 XM_029329709.2 4161 3945 2200 5855 5215 Q8VEM8 7.9e-177 Phosphate carrier protein, mitochondrial (Phosphate transport protein) (PTP) (Solute carrier family 25 member 3) Mus musculus (Mouse) mitochondrial phosphate ion transmembrane transport [GO:1990547]; phosphate ion transmembrane transport [GO:0035435] GO:0005315; GO:0005739; GO:0005743; GO:0015293; GO:0035435; GO:0043209; GO:0044877; GO:1990547 43827 XM_044325563.1 22 0 3 6 11 NA NA NA NA NA NA 43828 XM_044320405.1 0 0 43 0 0 NA NA NA NA NA NA 43829 XM_044314711.1 295 490 389 183 176 Q7RTR2 3e-41 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 43830 XM_044314711.1 295 490 389 183 176 Q7RTR2 9e-40 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 43831 XM_044314711.1 295 490 389 183 176 Q7RTR2 7.05e-39 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 43832 XM_044314711.1 295 490 389 183 176 Q7RTR2 8.25e-37 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 43833 XM_044314711.1 295 490 389 183 176 Q7RTR2 2.3e-35 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 43834 XM_044320376.1 0 0 0 3 6 NA NA NA NA NA NA 43835 XM_029339586.2 74 33 48 46 98 NA NA NA NA NA NA 43836 XM_044310353.1 26 19 0 0 8 NA NA NA NA NA NA 43837 XR_003824262.2 1296 396 503 757 679 NA NA NA NA NA NA 43838 XM_029343388.2 147 44 61 53 170 NA NA NA NA NA NA 43839 XM_029333758.2 131 31 10 388 119 P16390 6.67e-102 Potassium voltage-gated channel subfamily A member 3 (MK3) (Voltage-gated potassium channel subunit Kv1.3) Mus musculus (Mouse) corpus callosum development [GO:0022038]; optic nerve development [GO:0021554]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005251; GO:0005886; GO:0008076; GO:0015271; GO:0016020; GO:0021554; GO:0022038; GO:0030424; GO:0034765; GO:0042734; GO:0044305; GO:0045121; GO:0045211; GO:0051260; GO:0071805; GO:0098978 43840 XM_044321675.1 222 159 0 186 192 P35439 2.5e-53 Glutamate receptor ionotropic, NMDA 1 (GluN1) (Glutamate [NMDA] receptor subunit zeta-1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1) Rattus norvegicus (Rat) adult locomotory behavior [GO:0008344]; associative learning [GO:0008306]; calcium ion homeostasis [GO:0055074]; calcium ion transmembrane import into cytosol [GO:0097553]; calcium ion transport [GO:0006816]; cation transmembrane transport [GO:0098655]; cation transport [GO:0006812]; cellular calcium ion homeostasis [GO:0006874]; cellular response to manganese ion [GO:0071287]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; conditioned taste aversion [GO:0001661]; excitatory postsynaptic potential [GO:0060079]; ionotropic glutamate receptor signaling pathway [GO:0035235]; learning [GO:0007612]; learning or memory [GO:0007611]; long-term memory [GO:0007616]; male mating behavior [GO:0060179]; memory [GO:0007613]; negative regulation of neuron apoptotic process [GO:0043524]; neuromuscular process [GO:0050905]; neuron cellular homeostasis [GO:0070050]; olfactory learning [GO:0008355]; pons maturation [GO:0021586]; positive regulation of apoptotic process [GO:0043065]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of cell death [GO:0010942]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of dendritic spine maintenance [GO:1902952]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of Schwann cell migration [GO:1900149]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; prepulse inhibition [GO:0060134]; propylene metabolic process [GO:0018964]; protein heterotetramerization [GO:0051290]; protein localization to postsynaptic membrane [GO:1903539]; protein-containing complex assembly [GO:0065003]; regulation of axonogenesis [GO:0050770]; regulation of cation transmembrane transport [GO:1904062]; regulation of cell communication [GO:0010646]; regulation of dendrite morphogenesis [GO:0048814]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of membrane potential [GO:0042391]; regulation of neuron apoptotic process [GO:0043523]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of respiratory gaseous exchange [GO:0043576]; regulation of synapse assembly [GO:0051963]; regulation of synaptic plasticity [GO:0048167]; response to amine [GO:0014075]; response to amphetamine [GO:0001975]; response to calcium ion [GO:0051592]; response to ethanol [GO:0045471]; response to fungicide [GO:0060992]; response to glycine [GO:1905429]; response to morphine [GO:0043278]; response to organic cyclic compound [GO:0014070]; rhythmic process [GO:0048511]; sensory perception of pain [GO:0019233]; social behavior [GO:0035176]; startle response [GO:0001964]; suckling behavior [GO:0001967]; synaptic transmission, glutamatergic [GO:0035249]; transcription by RNA polymerase II [GO:0006366]; visual learning [GO:0008542] GO:0001540; GO:0001661; GO:0001964; GO:0001967; GO:0001975; GO:0004970; GO:0004972; GO:0005102; GO:0005261; GO:0005262; GO:0005509; GO:0005516; GO:0005737; GO:0005783; GO:0005789; GO:0005886; GO:0006366; GO:0006812; GO:0006816; GO:0006874; GO:0007268; GO:0007611; GO:0007612; GO:0007613; GO:0007616; GO:0008021; GO:0008306; GO:0008344; GO:0008355; GO:0008542; GO:0009986; GO:0010524; GO:0010646; GO:0010942; GO:0014069; GO:0014070; GO:0014075; GO:0015276; GO:0016020; GO:0016594; GO:0016595; GO:0017146; GO:0018964; GO:0019233; GO:0019899; GO:0019902; GO:0021586; GO:0021987; GO:0022843; GO:0022849; GO:0030425; GO:0030672; GO:0032590; GO:0035176; GO:0035235; GO:0035249; GO:0035254; GO:0038023; GO:0042165; GO:0042391; GO:0042734; GO:0043005; GO:0043025; GO:0043065; GO:0043083; GO:0043195; GO:0043197; GO:0043278; GO:0043523; GO:0043524; GO:0043576; GO:0044307; GO:0044877; GO:0045202; GO:0045211; GO:0045471; GO:0045944; GO:0048167; GO:0048168; GO:0048169; GO:0048511; GO:0048787; GO:0048814; GO:0050770; GO:0050905; GO:0051290; GO:0051592; GO:0051963; GO:0051968; GO:0055074; GO:0060076; GO:0060079; GO:0060134; GO:0060179; GO:0060992; GO:0065003; GO:0070050; GO:0071287; GO:0097060; GO:0097553; GO:0098655; GO:0098686; GO:0098688; GO:0098839; GO:0098978; GO:0099507; GO:1900149; GO:1902952; GO:1903428; GO:1903539; GO:1904062; GO:1904315; GO:1905429; GO:2000463; GO:2001056 43841 XM_029341489.2 339 260 224 387 625 Q8VCD6 6.3e-56 Receptor expression-enhancing protein 2 Mus musculus (Mouse) endoplasmic reticulum tubular network organization [GO:0071786]; protein transport into membrane raft [GO:0032596]; regulation of intracellular transport [GO:0032386]; sensory perception of bitter taste [GO:0050913]; sensory perception of sweet taste [GO:0050916] GO:0005783; GO:0005789; GO:0005881; GO:0005886; GO:0008017; GO:0016020; GO:0031883; GO:0032386; GO:0032596; GO:0050913; GO:0050916; GO:0071782; GO:0071786 43842 XM_044316928.1 0 446 0 432 0 NA NA NA NA NA NA 43843 XM_044316639.1 1979 1215 1217 2468 2419 Q6JAN0 0 Adhesion G-protein coupled receptor V1 (EC 3.4.-.-) (G-protein coupled receptor 98) (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) Danio rerio (Zebrafish) (Brachydanio rerio) cell surface receptor signaling pathway [GO:0007166]; cellular response to calcium ion [GO:0071277]; eye photoreceptor cell development [GO:0042462]; negative regulation of adenylate cyclase activity [GO:0007194]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase C signaling [GO:0090037]; regulation of protein stability [GO:0031647]; self proteolysis [GO:0097264]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] GO:0001917; GO:0001965; GO:0004930; GO:0005737; GO:0007166; GO:0007194; GO:0007601; GO:0007605; GO:0010739; GO:0010855; GO:0016787; GO:0031647; GO:0032420; GO:0042462; GO:0060171; GO:0071277; GO:0090037; GO:0097264 43844 XM_044316639.1 1979 1215 1217 2468 2419 Q6JAN0 0 Adhesion G-protein coupled receptor V1 (EC 3.4.-.-) (G-protein coupled receptor 98) (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) Danio rerio (Zebrafish) (Brachydanio rerio) cell surface receptor signaling pathway [GO:0007166]; cellular response to calcium ion [GO:0071277]; eye photoreceptor cell development [GO:0042462]; negative regulation of adenylate cyclase activity [GO:0007194]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase C signaling [GO:0090037]; regulation of protein stability [GO:0031647]; self proteolysis [GO:0097264]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] GO:0001917; GO:0001965; GO:0004930; GO:0005737; GO:0007166; GO:0007194; GO:0007601; GO:0007605; GO:0010739; GO:0010855; GO:0016787; GO:0031647; GO:0032420; GO:0042462; GO:0060171; GO:0071277; GO:0090037; GO:0097264 43845 XM_044316639.1 1979 1215 1217 2468 2419 Q6JAN0 1.76e-80 Adhesion G-protein coupled receptor V1 (EC 3.4.-.-) (G-protein coupled receptor 98) (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) Danio rerio (Zebrafish) (Brachydanio rerio) cell surface receptor signaling pathway [GO:0007166]; cellular response to calcium ion [GO:0071277]; eye photoreceptor cell development [GO:0042462]; negative regulation of adenylate cyclase activity [GO:0007194]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase C signaling [GO:0090037]; regulation of protein stability [GO:0031647]; self proteolysis [GO:0097264]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] GO:0001917; GO:0001965; GO:0004930; GO:0005737; GO:0007166; GO:0007194; GO:0007601; GO:0007605; GO:0010739; GO:0010855; GO:0016787; GO:0031647; GO:0032420; GO:0042462; GO:0060171; GO:0071277; GO:0090037; GO:0097264 43846 XM_044316639.1 1979 1215 1217 2468 2419 Q6JAN0 6.86e-68 Adhesion G-protein coupled receptor V1 (EC 3.4.-.-) (G-protein coupled receptor 98) (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) Danio rerio (Zebrafish) (Brachydanio rerio) cell surface receptor signaling pathway [GO:0007166]; cellular response to calcium ion [GO:0071277]; eye photoreceptor cell development [GO:0042462]; negative regulation of adenylate cyclase activity [GO:0007194]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase C signaling [GO:0090037]; regulation of protein stability [GO:0031647]; self proteolysis [GO:0097264]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] GO:0001917; GO:0001965; GO:0004930; GO:0005737; GO:0007166; GO:0007194; GO:0007601; GO:0007605; GO:0010739; GO:0010855; GO:0016787; GO:0031647; GO:0032420; GO:0042462; GO:0060171; GO:0071277; GO:0090037; GO:0097264 43847 XM_044316639.1 1979 1215 1217 2468 2419 Q6JAN0 1.37e-55 Adhesion G-protein coupled receptor V1 (EC 3.4.-.-) (G-protein coupled receptor 98) (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) Danio rerio (Zebrafish) (Brachydanio rerio) cell surface receptor signaling pathway [GO:0007166]; cellular response to calcium ion [GO:0071277]; eye photoreceptor cell development [GO:0042462]; negative regulation of adenylate cyclase activity [GO:0007194]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase C signaling [GO:0090037]; regulation of protein stability [GO:0031647]; self proteolysis [GO:0097264]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] GO:0001917; GO:0001965; GO:0004930; GO:0005737; GO:0007166; GO:0007194; GO:0007601; GO:0007605; GO:0010739; GO:0010855; GO:0016787; GO:0031647; GO:0032420; GO:0042462; GO:0060171; GO:0071277; GO:0090037; GO:0097264 43848 XM_044316639.1 1979 1215 1217 2468 2419 Q6JAN0 5.84e-53 Adhesion G-protein coupled receptor V1 (EC 3.4.-.-) (G-protein coupled receptor 98) (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) Danio rerio (Zebrafish) (Brachydanio rerio) cell surface receptor signaling pathway [GO:0007166]; cellular response to calcium ion [GO:0071277]; eye photoreceptor cell development [GO:0042462]; negative regulation of adenylate cyclase activity [GO:0007194]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase C signaling [GO:0090037]; regulation of protein stability [GO:0031647]; self proteolysis [GO:0097264]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] GO:0001917; GO:0001965; GO:0004930; GO:0005737; GO:0007166; GO:0007194; GO:0007601; GO:0007605; GO:0010739; GO:0010855; GO:0016787; GO:0031647; GO:0032420; GO:0042462; GO:0060171; GO:0071277; GO:0090037; GO:0097264 43849 XM_044316639.1 1979 1215 1217 2468 2419 Q6JAN0 6.3e-53 Adhesion G-protein coupled receptor V1 (EC 3.4.-.-) (G-protein coupled receptor 98) (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) Danio rerio (Zebrafish) (Brachydanio rerio) cell surface receptor signaling pathway [GO:0007166]; cellular response to calcium ion [GO:0071277]; eye photoreceptor cell development [GO:0042462]; negative regulation of adenylate cyclase activity [GO:0007194]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase C signaling [GO:0090037]; regulation of protein stability [GO:0031647]; self proteolysis [GO:0097264]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] GO:0001917; GO:0001965; GO:0004930; GO:0005737; GO:0007166; GO:0007194; GO:0007601; GO:0007605; GO:0010739; GO:0010855; GO:0016787; GO:0031647; GO:0032420; GO:0042462; GO:0060171; GO:0071277; GO:0090037; GO:0097264 43850 XM_044316639.1 1979 1215 1217 2468 2419 Q6JAN0 1.49e-51 Adhesion G-protein coupled receptor V1 (EC 3.4.-.-) (G-protein coupled receptor 98) (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) Danio rerio (Zebrafish) (Brachydanio rerio) cell surface receptor signaling pathway [GO:0007166]; cellular response to calcium ion [GO:0071277]; eye photoreceptor cell development [GO:0042462]; negative regulation of adenylate cyclase activity [GO:0007194]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase C signaling [GO:0090037]; regulation of protein stability [GO:0031647]; self proteolysis [GO:0097264]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] GO:0001917; GO:0001965; GO:0004930; GO:0005737; GO:0007166; GO:0007194; GO:0007601; GO:0007605; GO:0010739; GO:0010855; GO:0016787; GO:0031647; GO:0032420; GO:0042462; GO:0060171; GO:0071277; GO:0090037; GO:0097264 43851 XM_044316639.1 1979 1215 1217 2468 2419 Q6JAN0 6.79e-49 Adhesion G-protein coupled receptor V1 (EC 3.4.-.-) (G-protein coupled receptor 98) (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) Danio rerio (Zebrafish) (Brachydanio rerio) cell surface receptor signaling pathway [GO:0007166]; cellular response to calcium ion [GO:0071277]; eye photoreceptor cell development [GO:0042462]; negative regulation of adenylate cyclase activity [GO:0007194]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase C signaling [GO:0090037]; regulation of protein stability [GO:0031647]; self proteolysis [GO:0097264]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] GO:0001917; GO:0001965; GO:0004930; GO:0005737; GO:0007166; GO:0007194; GO:0007601; GO:0007605; GO:0010739; GO:0010855; GO:0016787; GO:0031647; GO:0032420; GO:0042462; GO:0060171; GO:0071277; GO:0090037; GO:0097264 43852 XM_044316639.1 1979 1215 1217 2468 2419 Q6JAN0 2.94e-48 Adhesion G-protein coupled receptor V1 (EC 3.4.-.-) (G-protein coupled receptor 98) (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) Danio rerio (Zebrafish) (Brachydanio rerio) cell surface receptor signaling pathway [GO:0007166]; cellular response to calcium ion [GO:0071277]; eye photoreceptor cell development [GO:0042462]; negative regulation of adenylate cyclase activity [GO:0007194]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase C signaling [GO:0090037]; regulation of protein stability [GO:0031647]; self proteolysis [GO:0097264]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] GO:0001917; GO:0001965; GO:0004930; GO:0005737; GO:0007166; GO:0007194; GO:0007601; GO:0007605; GO:0010739; GO:0010855; GO:0016787; GO:0031647; GO:0032420; GO:0042462; GO:0060171; GO:0071277; GO:0090037; GO:0097264 43853 XM_044316639.1 1979 1215 1217 2468 2419 Q6JAN0 1.26e-45 Adhesion G-protein coupled receptor V1 (EC 3.4.-.-) (G-protein coupled receptor 98) (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) Danio rerio (Zebrafish) (Brachydanio rerio) cell surface receptor signaling pathway [GO:0007166]; cellular response to calcium ion [GO:0071277]; eye photoreceptor cell development [GO:0042462]; negative regulation of adenylate cyclase activity [GO:0007194]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase C signaling [GO:0090037]; regulation of protein stability [GO:0031647]; self proteolysis [GO:0097264]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] GO:0001917; GO:0001965; GO:0004930; GO:0005737; GO:0007166; GO:0007194; GO:0007601; GO:0007605; GO:0010739; GO:0010855; GO:0016787; GO:0031647; GO:0032420; GO:0042462; GO:0060171; GO:0071277; GO:0090037; GO:0097264 43854 XM_044316639.1 1979 1215 1217 2468 2419 Q6JAN0 4.43e-41 Adhesion G-protein coupled receptor V1 (EC 3.4.-.-) (G-protein coupled receptor 98) (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) Danio rerio (Zebrafish) (Brachydanio rerio) cell surface receptor signaling pathway [GO:0007166]; cellular response to calcium ion [GO:0071277]; eye photoreceptor cell development [GO:0042462]; negative regulation of adenylate cyclase activity [GO:0007194]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase C signaling [GO:0090037]; regulation of protein stability [GO:0031647]; self proteolysis [GO:0097264]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] GO:0001917; GO:0001965; GO:0004930; GO:0005737; GO:0007166; GO:0007194; GO:0007601; GO:0007605; GO:0010739; GO:0010855; GO:0016787; GO:0031647; GO:0032420; GO:0042462; GO:0060171; GO:0071277; GO:0090037; GO:0097264 43855 XM_044316639.1 1979 1215 1217 2468 2419 Q6JAN0 3.46e-39 Adhesion G-protein coupled receptor V1 (EC 3.4.-.-) (G-protein coupled receptor 98) (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) Danio rerio (Zebrafish) (Brachydanio rerio) cell surface receptor signaling pathway [GO:0007166]; cellular response to calcium ion [GO:0071277]; eye photoreceptor cell development [GO:0042462]; negative regulation of adenylate cyclase activity [GO:0007194]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase C signaling [GO:0090037]; regulation of protein stability [GO:0031647]; self proteolysis [GO:0097264]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] GO:0001917; GO:0001965; GO:0004930; GO:0005737; GO:0007166; GO:0007194; GO:0007601; GO:0007605; GO:0010739; GO:0010855; GO:0016787; GO:0031647; GO:0032420; GO:0042462; GO:0060171; GO:0071277; GO:0090037; GO:0097264 43856 XM_044316639.1 1979 1215 1217 2468 2419 Q6JAN0 3.81e-33 Adhesion G-protein coupled receptor V1 (EC 3.4.-.-) (G-protein coupled receptor 98) (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) Danio rerio (Zebrafish) (Brachydanio rerio) cell surface receptor signaling pathway [GO:0007166]; cellular response to calcium ion [GO:0071277]; eye photoreceptor cell development [GO:0042462]; negative regulation of adenylate cyclase activity [GO:0007194]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase C signaling [GO:0090037]; regulation of protein stability [GO:0031647]; self proteolysis [GO:0097264]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] GO:0001917; GO:0001965; GO:0004930; GO:0005737; GO:0007166; GO:0007194; GO:0007601; GO:0007605; GO:0010739; GO:0010855; GO:0016787; GO:0031647; GO:0032420; GO:0042462; GO:0060171; GO:0071277; GO:0090037; GO:0097264 43857 XM_044316639.1 1979 1215 1217 2468 2419 Q6JAN0 2.93e-28 Adhesion G-protein coupled receptor V1 (EC 3.4.-.-) (G-protein coupled receptor 98) (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) Danio rerio (Zebrafish) (Brachydanio rerio) cell surface receptor signaling pathway [GO:0007166]; cellular response to calcium ion [GO:0071277]; eye photoreceptor cell development [GO:0042462]; negative regulation of adenylate cyclase activity [GO:0007194]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase C signaling [GO:0090037]; regulation of protein stability [GO:0031647]; self proteolysis [GO:0097264]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] GO:0001917; GO:0001965; GO:0004930; GO:0005737; GO:0007166; GO:0007194; GO:0007601; GO:0007605; GO:0010739; GO:0010855; GO:0016787; GO:0031647; GO:0032420; GO:0042462; GO:0060171; GO:0071277; GO:0090037; GO:0097264 43858 XM_044316639.1 1979 1215 1217 2468 2419 Q6JAN0 5.05e-28 Adhesion G-protein coupled receptor V1 (EC 3.4.-.-) (G-protein coupled receptor 98) (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) Danio rerio (Zebrafish) (Brachydanio rerio) cell surface receptor signaling pathway [GO:0007166]; cellular response to calcium ion [GO:0071277]; eye photoreceptor cell development [GO:0042462]; negative regulation of adenylate cyclase activity [GO:0007194]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase C signaling [GO:0090037]; regulation of protein stability [GO:0031647]; self proteolysis [GO:0097264]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] GO:0001917; GO:0001965; GO:0004930; GO:0005737; GO:0007166; GO:0007194; GO:0007601; GO:0007605; GO:0010739; GO:0010855; GO:0016787; GO:0031647; GO:0032420; GO:0042462; GO:0060171; GO:0071277; GO:0090037; GO:0097264 43859 XM_044316639.1 1979 1215 1217 2468 2419 Q6JAN0 1.14e-26 Adhesion G-protein coupled receptor V1 (EC 3.4.-.-) (G-protein coupled receptor 98) (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) Danio rerio (Zebrafish) (Brachydanio rerio) cell surface receptor signaling pathway [GO:0007166]; cellular response to calcium ion [GO:0071277]; eye photoreceptor cell development [GO:0042462]; negative regulation of adenylate cyclase activity [GO:0007194]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase C signaling [GO:0090037]; regulation of protein stability [GO:0031647]; self proteolysis [GO:0097264]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] GO:0001917; GO:0001965; GO:0004930; GO:0005737; GO:0007166; GO:0007194; GO:0007601; GO:0007605; GO:0010739; GO:0010855; GO:0016787; GO:0031647; GO:0032420; GO:0042462; GO:0060171; GO:0071277; GO:0090037; GO:0097264 43860 XM_044316639.1 1979 1215 1217 2468 2419 Q6JAN0 9.25e-26 Adhesion G-protein coupled receptor V1 (EC 3.4.-.-) (G-protein coupled receptor 98) (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) Danio rerio (Zebrafish) (Brachydanio rerio) cell surface receptor signaling pathway [GO:0007166]; cellular response to calcium ion [GO:0071277]; eye photoreceptor cell development [GO:0042462]; negative regulation of adenylate cyclase activity [GO:0007194]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase C signaling [GO:0090037]; regulation of protein stability [GO:0031647]; self proteolysis [GO:0097264]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] GO:0001917; GO:0001965; GO:0004930; GO:0005737; GO:0007166; GO:0007194; GO:0007601; GO:0007605; GO:0010739; GO:0010855; GO:0016787; GO:0031647; GO:0032420; GO:0042462; GO:0060171; GO:0071277; GO:0090037; GO:0097264 43861 XM_044316639.1 1979 1215 1217 2468 2419 Q6JAN0 6.28e-22 Adhesion G-protein coupled receptor V1 (EC 3.4.-.-) (G-protein coupled receptor 98) (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) Danio rerio (Zebrafish) (Brachydanio rerio) cell surface receptor signaling pathway [GO:0007166]; cellular response to calcium ion [GO:0071277]; eye photoreceptor cell development [GO:0042462]; negative regulation of adenylate cyclase activity [GO:0007194]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase C signaling [GO:0090037]; regulation of protein stability [GO:0031647]; self proteolysis [GO:0097264]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] GO:0001917; GO:0001965; GO:0004930; GO:0005737; GO:0007166; GO:0007194; GO:0007601; GO:0007605; GO:0010739; GO:0010855; GO:0016787; GO:0031647; GO:0032420; GO:0042462; GO:0060171; GO:0071277; GO:0090037; GO:0097264 43862 XM_044323778.1 53 10 19 53 57 NA NA NA NA NA NA 43863 XM_044315909.1 3 3 0 25 9 NA NA NA NA NA NA 43864 XM_029347442.2 24 67 15 22 19 NA NA NA NA NA NA 43865 XM_029357679.2 126 59 32 0 0 A1L1W9 5.17e-59 Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10) Danio rerio (Zebrafish) (Brachydanio rerio) aromatic amino acid transport [GO:0015801]; thyroid hormone transport [GO:0070327] GO:0005302; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0070327 43866 XM_044317826.1 191 0 14 0 115 Q2XWK0 1.69e-155 Synaptic vesicle 2-related protein (SV2-related protein) Xenopus laevis (African clawed frog) NA GO:0022857; GO:0030672 43867 XR_006392646.1 55 99 45 38 26 NA NA NA NA NA NA 43868 XM_029350882.2 619 1026 260 1291 419 NA NA NA NA NA NA 43869 XR_006397006.1 3 0 3 1 11 NA NA NA NA NA NA 43870 XM_029351180.2 28 0 0 0 18 NA NA NA NA NA NA 43871 XM_029334361.2 54 38 35 20 54 NA NA NA NA NA NA 43872 XM_029333905.2 9115 18070 6067 14086 6033 Q17770 1.17e-179 Protein disulfide-isomerase 2 (EC 5.3.4.1) (PDI 1) (Prolyl 4-hydroxylase subunit beta-2) Caenorhabditis elegans endoplasmic reticulum unfolded protein response [GO:0030968]; macromolecule modification [GO:0043412]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; protein deglutathionylation [GO:0080058]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976] GO:0003756; GO:0003810; GO:0005783; GO:0005788; GO:0006457; GO:0016222; GO:0018401; GO:0030968; GO:0034976; GO:0043412; GO:0080058 43873 XM_029338881.2 362 176 71 189 39 NA NA NA NA NA NA 43874 XM_029332969.2 161 105 125 40 134 Q9NW07 1.64e-38 Zinc finger protein 358 Homo sapiens (Human) embryonic forelimb morphogenesis [GO:0035115]; neural tube development [GO:0021915]; regulation of transcription by RNA polymerase II [GO:0006357]; stem cell population maintenance [GO:0019827] GO:0000978; GO:0003700; GO:0005634; GO:0006357; GO:0019827; GO:0021915; GO:0035115; GO:0046872 43875 XM_029332969.2 161 105 125 40 134 Q9NW07 5.5e-37 Zinc finger protein 358 Homo sapiens (Human) embryonic forelimb morphogenesis [GO:0035115]; neural tube development [GO:0021915]; regulation of transcription by RNA polymerase II [GO:0006357]; stem cell population maintenance [GO:0019827] GO:0000978; GO:0003700; GO:0005634; GO:0006357; GO:0019827; GO:0021915; GO:0035115; GO:0046872 43876 XM_029332969.2 161 105 125 40 134 Q9NW07 1.4e-34 Zinc finger protein 358 Homo sapiens (Human) embryonic forelimb morphogenesis [GO:0035115]; neural tube development [GO:0021915]; regulation of transcription by RNA polymerase II [GO:0006357]; stem cell population maintenance [GO:0019827] GO:0000978; GO:0003700; GO:0005634; GO:0006357; GO:0019827; GO:0021915; GO:0035115; GO:0046872 43877 XM_029332969.2 161 105 125 40 134 Q9NW07 1.11e-26 Zinc finger protein 358 Homo sapiens (Human) embryonic forelimb morphogenesis [GO:0035115]; neural tube development [GO:0021915]; regulation of transcription by RNA polymerase II [GO:0006357]; stem cell population maintenance [GO:0019827] GO:0000978; GO:0003700; GO:0005634; GO:0006357; GO:0019827; GO:0021915; GO:0035115; GO:0046872 43878 XR_006391899.1 27 25 42 4 48 NA NA NA NA NA NA 43879 XM_044324926.1 570 651 454 599 813 Q4R3D4 1.22e-45 Elongation factor 1-delta (EF-1-delta) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0003677; GO:0003746; GO:0005634; GO:0005853 43880 XM_029358039.2 0 25 0 13 35 P31646 0 Sodium- and chloride-dependent GABA transporter 2 (GAT-2) (Solute carrier family 6 member 13) Rattus norvegicus (Rat) amino acid import across plasma membrane [GO:0089718]; creatine transmembrane transport [GO:0015881]; gamma-aminobutyric acid import [GO:0051939]; monocarboxylic acid transport [GO:0015718]; neurotransmitter transport [GO:0006836]; nitrogen compound transport [GO:0071705]; positive regulation of necrotic cell death [GO:0010940]; sodium ion transmembrane transport [GO:0035725]; taurine transport [GO:0015734] GO:0005283; GO:0005308; GO:0005332; GO:0005368; GO:0005369; GO:0005886; GO:0006836; GO:0008028; GO:0010940; GO:0015171; GO:0015185; GO:0015718; GO:0015734; GO:0015881; GO:0016323; GO:0035725; GO:0042165; GO:0043005; GO:0051939; GO:0071705; GO:0089718 43881 XM_044323376.1 17 3 0 28 21 NA NA NA NA NA NA 43882 XM_044318939.1 364 0 215 20 114 Q58A42 2.35e-73 Protein DD3-3 Dictyostelium discoideum (Social amoeba) NA GO:0016020 43883 XM_029329661.2 520 284 191 437 351 Q8IXR9 6.48e-57 Uncharacterized protein C12orf56 Homo sapiens (Human) NA NA 43884 XM_044311596.1 983 572 547 702 1170 Q6DI40 1.87e-40 Tetratricopeptide repeat protein 33 (TPR repeat protein 33) Danio rerio (Zebrafish) (Brachydanio rerio) NA NA 43885 XM_029334105.2 978 919 647 805 861 Q32NG4 6.28e-87 Glutamine amidotransferase-like class 1 domain-containing protein 1 (Parkinson disease 7 domain-containing protein 1) Xenopus laevis (African clawed frog) NA GO:0005576 43886 XM_029355885.2 289 144 218 286 399 NA NA NA NA NA NA 43887 XM_029354645.2 6 7 5 10 19 NA NA NA NA NA NA 43888 XM_029357603.2 56 53 24 63 92 Q14565 0 Meiotic recombination protein DMC1/LIM15 homolog Homo sapiens (Human) chromosome organization involved in meiotic cell cycle [GO:0070192]; DNA recombinase assembly [GO:0000730]; female gamete generation [GO:0007292]; homologous chromosome pairing at meiosis [GO:0007129]; male meiosis I [GO:0007141]; meiotic cell cycle [GO:0051321]; mitotic recombination [GO:0006312]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; reciprocal meiotic recombination [GO:0007131]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]; strand invasion [GO:0042148] GO:0000150; GO:0000730; GO:0000781; GO:0000794; GO:0001541; GO:0001556; GO:0003677; GO:0003690; GO:0003697; GO:0005524; GO:0005634; GO:0005694; GO:0006312; GO:0007129; GO:0007131; GO:0007141; GO:0007283; GO:0007286; GO:0007292; GO:0008094; GO:0042148; GO:0042802; GO:0051321; GO:0070192; GO:0140664 43889 XM_044323756.1 0 0 0 0 6 NA NA NA NA NA NA 43890 XM_029346656.2 358 265 196 365 398 P56433 1.05e-41 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5 (EC 2.4.1.152) (3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT5) (EC 2.4.1.65) (Fucosyltransferase 5) (Fucosyltransferase V) (Fuc-TV) (FucT-V) (Galactoside 3-L-fucosyltransferase) Pan troglodytes (Chimpanzee) ceramide metabolic process [GO:0006672]; fucosylation [GO:0036065]; oligosaccharide metabolic process [GO:0009311]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493] GO:0006487; GO:0006493; GO:0006672; GO:0009311; GO:0017060; GO:0017083; GO:0032580; GO:0036065; GO:0046920 43891 XM_029353019.2 14 0 3 0 27 NA NA NA NA NA NA 43892 XM_044327708.1 25 0 37 6 30 NA NA NA NA NA NA 43893 XM_029330991.2 413 244 148 454 562 P0CB05 1.09e-57 Centrosomal protein of 63 kDa (Cep63) Gallus gallus (Chicken) cell division [GO:0051301]; centriole replication [GO:0007099]; de novo centriole assembly involved in multi-ciliated epithelial cell differentiation [GO:0098535]; DNA damage checkpoint signaling [GO:0000077]; signal transduction in response to DNA damage [GO:0042770]; spindle assembly [GO:0051225] GO:0000077; GO:0000922; GO:0005737; GO:0005813; GO:0005814; GO:0007099; GO:0042770; GO:0051225; GO:0051301; GO:0098535 43894 XM_044307642.1 0 11 6 20 7 P79385 2.21e-24 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (SED1) (Sperm surface protein SP47) (PP47) Sus scrofa (Pig) angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; single fertilization [GO:0007338] GO:0001525; GO:0002080; GO:0005576; GO:0007155; GO:0007338 43895 XM_044317995.1 90 77 35 68 81 NA NA NA NA NA NA 43896 XM_044317797.1 1911 1193 995 1797 2028 Q8IVF4 0 Dynein axonemal heavy chain 10 (Axonemal beta dynein heavy chain 10) (Ciliary dynein heavy chain 10) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0045505; GO:0051959; GO:0097729 43897 XR_006391554.1 26 0 1 0 24 NA NA NA NA NA NA 43898 XM_044319284.1 790 387 290 451 571 Q1NZ26 9.35e-68 Uncharacterized protein F13E9.13, mitochondrial Caenorhabditis elegans NA GO:0005739 43899 XM_044319435.1 0 0 4 10 21 NA NA NA NA NA NA 43900 XM_029358664.2 522 453 382 282 235 NA NA NA NA NA NA 43901 XM_029356047.2 415 244 170 789 201 O73888 7.15e-35 Hematopoietic prostaglandin D synthase (H-PGDS) (EC 5.3.99.2) (GST class-sigma) (Glutathione S-transferase) (EC 2.5.1.18) (Glutathione-dependent PGD synthase) (Glutathione-requiring prostaglandin D synthase) (Prostaglandin-H2 D-isomerase) Gallus gallus (Chicken) glutathione metabolic process [GO:0006749]; prostaglandin biosynthetic process [GO:0001516]; prostaglandin metabolic process [GO:0006693] GO:0000287; GO:0001516; GO:0004364; GO:0004667; GO:0005509; GO:0005737; GO:0006693; GO:0006749 43902 XM_029325684.2 84 19 73 157 40 NA NA NA NA NA NA 43903 XR_006393475.1 24 0 5 11 2 NA NA NA NA NA NA 43904 XM_044313062.1 0 0 8 0 19 Q96AY4 6.15e-49 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 43905 XM_044313062.1 0 0 8 0 19 Q96AY4 2.94e-47 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 43906 XM_044313062.1 0 0 8 0 19 Q96AY4 9.32e-45 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 43907 XM_044313062.1 0 0 8 0 19 Q96AY4 1.93e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 43908 XM_044313062.1 0 0 8 0 19 Q96AY4 1.14e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 43909 XM_044313062.1 0 0 8 0 19 Q96AY4 6.36e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 43910 XM_044313062.1 0 0 8 0 19 Q96AY4 1.48e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 43911 XM_044313062.1 0 0 8 0 19 Q96AY4 5.56e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 43912 XM_044313062.1 0 0 8 0 19 Q96AY4 7.48e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 43913 XM_044313062.1 0 0 8 0 19 Q96AY4 6.57e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 43914 XM_044313062.1 0 0 8 0 19 Q96AY4 2.21e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 43915 XM_044313062.1 0 0 8 0 19 Q96AY4 3.45e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 43916 XM_044313062.1 0 0 8 0 19 Q96AY4 4.81e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 43917 XM_044313062.1 0 0 8 0 19 Q96AY4 5.02e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 43918 XM_044313062.1 0 0 8 0 19 Q96AY4 5.58e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 43919 XM_044313062.1 0 0 8 0 19 Q96AY4 1.04e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 43920 XM_044315262.1 62 29 33 685 34 Q5DU56 1.53e-45 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 43921 XM_044315262.1 62 29 33 685 34 Q5DU56 1.67e-42 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 43922 XM_044315262.1 62 29 33 685 34 Q5DU56 1.18e-38 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 43923 XM_044315262.1 62 29 33 685 34 Q5DU56 2.91e-25 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 43924 XM_044315262.1 62 29 33 685 34 Q5DU56 2.31e-24 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 43925 XM_029350231.2 941 675 540 1027 1021 P91580 3.58e-73 Putative Ras-related protein Rab-33 Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis) Rab protein signal transduction [GO:0032482] GO:0003924; GO:0005525; GO:0005768; GO:0005794; GO:0005886; GO:0032482 43926 XM_044316976.1 218 211 217 114 174 NA NA NA NA NA NA 43927 XM_044328751.1 237 171 211 297 249 Q8VCY6 4.25e-100 U3 small nucleolar RNA-associated protein 6 homolog (Multiple hat domains protein) Mus musculus (Mouse) maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462] GO:0000462; GO:0005694; GO:0005730; GO:0030515; GO:0032040; GO:0034388 43928 XM_044322904.1 0 0 0 132 25 Q95SX7 6.38e-26 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 43929 XM_044308393.1 2178 2569 1037 2246 1620 NA NA NA NA NA NA 43930 XM_029332688.2 127 69 25 87 79 Q9BVM2 9.52e-61 Protein DPCD Homo sapiens (Human) determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; lateral ventricle development [GO:0021670]; spermatogenesis [GO:0007283]; third ventricle development [GO:0021678] GO:0003351; GO:0005576; GO:0005634; GO:0007283; GO:0007368; GO:0021670; GO:0021678; GO:0030317; GO:0051649 43931 XM_029332408.2 215 258 134 191 193 Q8BG58 1.82e-72 Transmembrane prolyl 4-hydroxylase (P4H-TM) (EC 1.14.11.29) (Hypoxia-inducible factor prolyl hydroxylase 4) (HIF-PH4) (HIF-prolyl hydroxylase 4) (HPH-4) Mus musculus (Mouse) peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; regulation of erythrocyte differentiation [GO:0045646] GO:0004656; GO:0005506; GO:0005509; GO:0005783; GO:0005789; GO:0016706; GO:0018401; GO:0031418; GO:0045646 43932 XM_029332408.2 215 258 134 191 193 Q8BG58 1.84e-65 Transmembrane prolyl 4-hydroxylase (P4H-TM) (EC 1.14.11.29) (Hypoxia-inducible factor prolyl hydroxylase 4) (HIF-PH4) (HIF-prolyl hydroxylase 4) (HPH-4) Mus musculus (Mouse) peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; regulation of erythrocyte differentiation [GO:0045646] GO:0004656; GO:0005506; GO:0005509; GO:0005783; GO:0005789; GO:0016706; GO:0018401; GO:0031418; GO:0045646 43933 XM_044311703.1 19 7 23 56 80 NA NA NA NA NA NA 43934 XR_006393283.1 16 13 9 9 0 NA NA NA NA NA NA 43935 XM_029355015.2 93 117 132 52 225 O43897 5.2e-28 Tolloid-like protein 1 (EC 3.4.24.-) Homo sapiens (Human) cell differentiation [GO:0030154]; collagen fibril organization [GO:0030199]; dorsal/ventral pattern formation [GO:0009953]; protein processing [GO:0016485]; skeletal system development [GO:0001501] GO:0001501; GO:0004222; GO:0004252; GO:0005509; GO:0005576; GO:0005615; GO:0008270; GO:0009953; GO:0016485; GO:0030154; GO:0030199 43936 XM_029358027.2 404 378 256 1048 776 P50549 3.75e-61 ETS translocation variant 1 (Ets-related protein 81) Homo sapiens (Human) axon guidance [GO:0007411]; cell differentiation [GO:0030154]; mechanosensory behavior [GO:0007638]; muscle organ development [GO:0007517]; peripheral nervous system neuron development [GO:0048935]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366] GO:0000785; GO:0000978; GO:0000981; GO:0001228; GO:0003700; GO:0005634; GO:0006357; GO:0006366; GO:0007411; GO:0007517; GO:0007638; GO:0030154; GO:0045944; GO:0048935; GO:1990837 43937 XM_029355524.2 239 170 63 155 278 O73754 3.39e-21 Gremlin-1 (Cysteine knot superfamily 1, BMP antagonist 1) Xenopus laevis (African clawed frog) determination of dorsal identity [GO:0048263]; nervous system development [GO:0007399]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; pronephric duct development [GO:0039022]; sequestering of BMP in extracellular matrix [GO:0035582]; somite rostral/caudal axis specification [GO:0032525] GO:0005125; GO:0005615; GO:0007399; GO:0014029; GO:0014032; GO:0016015; GO:0032525; GO:0035582; GO:0036122; GO:0039022; GO:0048263 43938 XR_006395272.1 0 0 0 0 25 NA NA NA NA NA NA 43939 XR_006397848.1 0 46 0 0 0 NA NA NA NA NA NA 43940 XM_029345941.2 134 162 36 103 46 NA NA NA NA NA NA 43941 XM_029344649.2 449 2313 952 1617 1006 Q99L04 4.71e-101 Dehydrogenase/reductase SDR family member 1 (EC 1.1.1.-) (Short chain dehydrogenase/reductase family 19C member 1) (Protein SDR19C1) Mus musculus (Mouse) NA GO:0004090; GO:0005739; GO:0005743; GO:0005783; GO:0016616; GO:0047045 43942 XM_029335653.2 3302 350 38 293 293 Q08AE8 1.42e-46 Protein spire homolog 1 (Spir-1) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; actin filament network formation [GO:0051639]; actin filament polymerization [GO:0030041]; actin nucleation [GO:0045010]; cleavage furrow formation [GO:0036089]; establishment of meiotic spindle localization [GO:0051295]; formin-nucleated actin cable assembly [GO:0070649]; Golgi vesicle transport [GO:0048193]; innate immune response [GO:0045087]; intracellular transport [GO:0046907]; polar body extrusion after meiotic divisions [GO:0040038]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of mitochondrial fission [GO:0090141]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] GO:0003779; GO:0005654; GO:0005741; GO:0005829; GO:0005856; GO:0005886; GO:0005938; GO:0015031; GO:0016192; GO:0030036; GO:0030041; GO:0030659; GO:0036089; GO:0040038; GO:0045010; GO:0045087; GO:0046907; GO:0048193; GO:0048471; GO:0051295; GO:0051639; GO:0070649; GO:0090141; GO:2000781 43943 XM_044322076.1 203 305 284 896 1081 Q8IZH2 0 5'-3' exoribonuclease 1 (EC 3.1.13.-) (Strand-exchange protein 1 homolog) Homo sapiens (Human) cellular response to cycloheximide [GO:0071409]; cellular response to puromycin [GO:1905795]; histone mRNA catabolic process [GO:0071044]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of translation [GO:0017148]; nuclear mRNA surveillance [GO:0071028]; nuclear-transcribed mRNA catabolic process [GO:0000956]; response to testosterone [GO:0033574]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; rRNA catabolic process [GO:0016075] GO:0000932; GO:0000956; GO:0002151; GO:0003723; GO:0004534; GO:0005634; GO:0005829; GO:0005886; GO:0016020; GO:0016075; GO:0017148; GO:0030425; GO:0032211; GO:0033574; GO:0043025; GO:0045202; GO:0051880; GO:0070034; GO:0071028; GO:0071044; GO:0071409; GO:0090503; GO:1905795 43944 XM_044324929.1 143 123 136 220 155 NA NA NA NA NA NA 43945 XM_044319706.1 6940 6975 4931 7585 8813 Q62638 0 Golgi apparatus protein 1 (E-selectin ligand 1) (ESL-1) (Golgi sialoglycoprotein MG-160) Rattus norvegicus (Rat) bone morphogenesis [GO:0060349]; intracellular protein transport [GO:0006886]; negative regulation of protein processing [GO:0010955]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; protein processing [GO:0016485]; regulation of chondrocyte differentiation [GO:0032330]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0000139; GO:0005794; GO:0005797; GO:0005856; GO:0006886; GO:0007179; GO:0010955; GO:0016485; GO:0017134; GO:0030512; GO:0031012; GO:0032330; GO:0043231; GO:0060349 43946 XM_044313224.1 0 52 0 80 0 Q90511 1.81e-114 Translation initiation factor eIF-2B subunit beta (S20I15) (eIF-2B GDP-GTP exchange factor subunit beta) Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) central nervous system development [GO:0007417]; myelination [GO:0042552]; oligodendrocyte development [GO:0014003]; T cell receptor signaling pathway [GO:0050852]; translational initiation [GO:0006413] GO:0003743; GO:0005524; GO:0005525; GO:0005737; GO:0005851; GO:0006413; GO:0007417; GO:0014003; GO:0042552; GO:0050852 43947 XM_029357448.2 211 68 0 0 162 Q80TC6 0 Zinc finger SWIM domain-containing protein 5 Mus musculus (Mouse) NA GO:0008270; GO:0031462 43948 XM_044318332.1 16 0 28 4 213 NA NA NA NA NA NA 43949 XM_044320207.1 0 13 0 0 0 NA NA NA NA NA NA 43950 XM_044323699.1 0 0 0 8 16 NA NA NA NA NA NA 43951 XM_044307618.1 0 0 0 0 140 NA NA NA NA NA NA 43952 XR_006392766.1 879 248 110 221 285 NA NA NA NA NA NA 43953 XM_029343124.2 597 472 285 405 454 Q9Z9A3 2.59e-24 50S ribosomal protein L1 Chlamydia pneumoniae (Chlamydophila pneumoniae) regulation of translation [GO:0006417]; translation [GO:0006412] GO:0000049; GO:0003735; GO:0006412; GO:0006417; GO:0015934; GO:0019843 43954 XM_029346912.2 781 429 540 410 671 O00716 1.78e-67 Transcription factor E2F3 (E2F-3) Homo sapiens (Human) G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of fat cell proliferation [GO:0070345]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; protein import into nucleus [GO:0006606]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription initiation at RNA polymerase II promoter [GO:0006367] GO:0000082; GO:0000785; GO:0000978; GO:0000981; GO:0000987; GO:0001216; GO:0001228; GO:0003700; GO:0005634; GO:0005654; GO:0006357; GO:0006367; GO:0006606; GO:0008284; GO:0043565; GO:0045944; GO:0046983; GO:0070345; GO:0090575; GO:1905461; GO:1990837 43955 XR_006395185.1 36 87 55 92 51 NA NA NA NA NA NA 43956 XM_029333887.2 1215 984 455 1450 1420 NA NA NA NA NA NA 43957 XM_044320390.1 85 77 63 116 150 NA NA NA NA NA NA 43958 XM_029326618.2 357 198 291 208 302 NA NA NA NA NA NA 43959 XM_029352586.2 0 0 38 0 265 NA NA NA NA NA NA 43960 XM_029351522.2 1004 2109 1964 3639 1895 NA NA NA NA NA NA 43961 XM_029347245.2 1524 954 636 1407 1702 Q86UA1 2.86e-177 Pre-mRNA-processing factor 39 (PRP39 homolog) Homo sapiens (Human) mRNA 5'-splice site recognition [GO:0000395] GO:0000243; GO:0000395; GO:0005685; GO:0071004 43962 XM_044316577.1 2970 1630 1652 3265 2969 O60293 6.75e-119 Zinc finger C3H1 domain-containing protein (Coiled-coil domain-containing protein 131) (Proline/serine-rich coiled-coil protein 2) Homo sapiens (Human) RNA processing [GO:0006396] GO:0000178; GO:0005615; GO:0005634; GO:0006396; GO:0046872 43963 XM_029355769.2 9 0 43 9 34 NA NA NA NA NA NA 43964 XM_044317162.1 0 33 5 23 5 NA NA NA NA NA NA 43965 XM_044321409.1 170 59 39 73 124 Q2M389 0 WASH complex subunit 4 (Strumpellin and WASH-interacting protein) (SWIP) (WASH complex subunit SWIP) Homo sapiens (Human) endosomal transport [GO:0016197]; endosome organization [GO:0007032]; nuclear envelope budding [GO:0140591]; protein transport [GO:0015031]; regulation of Arp2/3 complex-mediated actin nucleation [GO:0034315] GO:0005654; GO:0005768; GO:0007032; GO:0015031; GO:0016197; GO:0031901; GO:0034315; GO:0071203; GO:0140591 43966 XM_029328503.2 21062 27211 15734 21742 27921 NA NA NA NA NA NA 43967 XM_029355541.2 133 205 72 168 167 Q6GPP1 2.9e-146 Telomere length regulation protein TEL2 homolog Xenopus laevis (African clawed frog) NA GO:0000781; GO:0005634; GO:0005737; GO:0016020 43968 XR_003825150.1 5 0 0 6 3 NA NA NA NA NA NA 43969 XM_029355941.2 2044 1507 1523 1616 1186 Q969H0 0 F-box/WD repeat-containing protein 7 (Archipelago homolog) (hAgo) (F-box and WD-40 domain-containing protein 7) (F-box protein FBX30) (SEL-10) (hCdc4) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; DNA repair [GO:0006281]; lipid homeostasis [GO:0055088]; lung development [GO:0030324]; negative regulation of gene expression [GO:0010629]; negative regulation of hepatocyte proliferation [GO:2000346]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of osteoclast development [GO:2001205]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; negative regulation of SREBP signaling pathway [GO:2000639]; negative regulation of triglyceride biosynthetic process [GO:0010868]; Notch signaling pathway [GO:0007219]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903378]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein destabilization [GO:0031648]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of cell cycle G1/S phase transition [GO:1902806]; regulation of cell migration involved in sprouting angiogenesis [GO:0090049]; regulation of circadian rhythm [GO:0042752]; regulation of lipid storage [GO:0010883]; regulation of protein localization [GO:0032880]; rhythmic process [GO:0048511]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; sister chromatid cohesion [GO:0007062]; ubiquitin recycling [GO:0010992]; vasculature development [GO:0001944]; vasculogenesis [GO:0001570] GO:0001570; GO:0001944; GO:0005634; GO:0005654; GO:0005694; GO:0005730; GO:0005737; GO:0005739; GO:0005783; GO:0005794; GO:0005829; GO:0006281; GO:0006974; GO:0007062; GO:0007219; GO:0010629; GO:0010868; GO:0010883; GO:0010992; GO:0016567; GO:0019005; GO:0030324; GO:0030332; GO:0030674; GO:0031146; GO:0031398; GO:0031625; GO:0031648; GO:0032880; GO:0032991; GO:0034644; GO:0042752; GO:0042802; GO:0043130; GO:0043161; GO:0045741; GO:0045746; GO:0048471; GO:0048511; GO:0050816; GO:0050821; GO:0051443; GO:0055088; GO:0070374; GO:0090049; GO:0097027; GO:1901800; GO:1902806; GO:1903026; GO:1903146; GO:1903378; GO:1903955; GO:1990452; GO:2000060; GO:2000346; GO:2000639; GO:2001205 43970 XM_029344828.2 109 144 72 178 42 NA NA NA NA NA NA 43971 XM_029335355.2 0 55 62 14 65 P30884 3.5e-75 Bone morphogenetic protein 2-B (BMP-2-II) Xenopus laevis (African clawed frog) cartilage development [GO:0051216]; cell differentiation [GO:0030154]; ossification [GO:0001503] GO:0001503; GO:0005125; GO:0005615; GO:0008083; GO:0030154; GO:0051216 43972 XM_044328703.1 10 0 6 53 3 NA NA NA NA NA NA 43973 XM_029342222.2 0 0 51 0 276 NA NA NA NA NA NA 43974 XM_044316039.1 39 45 12 50 79 P46023 4.16e-91 G-protein coupled receptor GRL101 Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004930; GO:0005886 43975 XM_029354160.2 27 3 29 7 16 Q6R2W3 1.54e-21 SCAN domain-containing protein 3 (Transposon-derived Buster4 transposase-like protein) (Zinc finger BED domain-containing protein 9) Homo sapiens (Human) DNA integration [GO:0015074]; positive regulation of cell cycle [GO:0045787]; positive regulation of epithelial cell proliferation [GO:0050679] GO:0003676; GO:0005634; GO:0005737; GO:0015074; GO:0045787; GO:0050679 43976 XM_029348082.2 2025 1763 1235 1735 2369 NA NA NA NA NA NA 43977 XM_044307586.1 2 8 0 112 75 NA NA NA NA NA NA 43978 XM_044315238.1 49 0 13 64 21 NA NA NA NA NA NA 43979 XM_029341560.2 0 255 0 120 0 Q9P107 4.42e-98 GEM-interacting protein (GMIP) Homo sapiens (Human) activation of GTPase activity [GO:0090630]; intracellular signal transduction [GO:0035556]; negative regulation of GTPase activity [GO:0034260]; regulation of small GTPase mediated signal transduction [GO:0051056] GO:0005096; GO:0005654; GO:0005829; GO:0005886; GO:0034260; GO:0035556; GO:0046872; GO:0051056; GO:0090630 43980 XM_044317820.1 0 0 0 206 326 Q7KTX8 8.96e-66 Mediator of RNA polymerase II transcription subunit 13 (Mediator complex subunit 13) (Mediator complex subunit Skuld) (Protein blind spot) (Protein poils aux pattes) (dTRAP240) Drosophila melanogaster (Fruit fly) cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; compound eye development [GO:0048749]; imaginal disc-derived leg segmentation [GO:0036011]; larval somatic muscle development [GO:0007526]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; regulation of transcription by RNA polymerase II [GO:0006357]; sex comb development [GO:0045498]; transcription initiation at RNA polymerase II promoter [GO:0006367]; wing disc dorsal/ventral pattern formation [GO:0048190] GO:0003712; GO:0005634; GO:0005654; GO:0006357; GO:0006367; GO:0007526; GO:0016592; GO:0022416; GO:0036011; GO:0045165; GO:0045498; GO:0048190; GO:0048749; GO:0070847; GO:0090263 43981 XM_044317820.1 0 0 0 206 326 Q7KTX8 6.28e-46 Mediator of RNA polymerase II transcription subunit 13 (Mediator complex subunit 13) (Mediator complex subunit Skuld) (Protein blind spot) (Protein poils aux pattes) (dTRAP240) Drosophila melanogaster (Fruit fly) cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; compound eye development [GO:0048749]; imaginal disc-derived leg segmentation [GO:0036011]; larval somatic muscle development [GO:0007526]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; regulation of transcription by RNA polymerase II [GO:0006357]; sex comb development [GO:0045498]; transcription initiation at RNA polymerase II promoter [GO:0006367]; wing disc dorsal/ventral pattern formation [GO:0048190] GO:0003712; GO:0005634; GO:0005654; GO:0006357; GO:0006367; GO:0007526; GO:0016592; GO:0022416; GO:0036011; GO:0045165; GO:0045498; GO:0048190; GO:0048749; GO:0070847; GO:0090263 43982 XM_029336764.2 1935 1880 99 148 436 Q9WU63 1.26e-35 Heme-binding protein 2 (Protein SOUL) Mus musculus (Mouse) negative regulation of mitochondrial membrane potential [GO:0010917]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of necrotic cell death [GO:0010940] GO:0005737; GO:0005739; GO:0010917; GO:0010940; GO:0020037; GO:0035794 43983 XR_006392309.1 25 28 27 12 37 Q15485 2.6e-76 Ficolin-2 (37 kDa elastin-binding protein) (Collagen/fibrinogen domain-containing protein 2) (EBP-37) (Ficolin-B) (Ficolin-beta) (Hucolin) (L-ficolin) (Serum lectin p35) Homo sapiens (Human) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; positive regulation of opsonization [GO:1903028]; proteolysis [GO:0006508]; recognition of apoptotic cell [GO:0043654] GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005576; GO:0005581; GO:0005615; GO:0006508; GO:0008228; GO:0009897; GO:0042802; GO:0043394; GO:0043654; GO:0046872; GO:0048306; GO:0050829; GO:0050830; GO:0062023; GO:0070062; GO:0072562; GO:0097367; GO:1903028; GO:1905370; GO:2001065 43984 XR_003822875.2 102 25 414 138 45 NA NA NA NA NA NA 43985 XR_006395360.1 11 18 51 100 64 NA NA NA NA NA NA 43986 XR_006393811.1 41 2 25 5 151 NA NA NA NA NA NA 43987 XM_029349101.2 146 246 154 266 301 NA NA NA NA NA NA 43988 XM_029345004.2 51 25 33 39 26 NA NA NA NA NA NA 43989 XR_006393091.1 0 0 17 1 0 NA NA NA NA NA NA 43990 XM_029337454.2 2069 2266 1305 1501 1361 Q8VCE2 6.4e-135 GPN-loop GTPase 1 (EC 3.6.5.-) (MBD2-interacting protein) (MBDin) (XPA-binding protein 1) Mus musculus (Mouse) NA GO:0003924; GO:0005525; GO:0005654; GO:0005739; GO:0005829 43991 XM_029337271.2 1 674 619 556 140 NA NA NA NA NA NA 43992 XM_029339358.2 698 948 752 579 688 NA NA NA NA NA NA 43993 XM_029350328.2 1 0 0 0 6 NA NA NA NA NA NA 43994 XM_029353836.2 6261 5764 4404 7754 7477 A6H7G2 2.28e-43 Drebrin-like protein Bos taurus (Bovine) adaptive immune response [GO:0002250]; endocytosis [GO:0006897]; neuron projection morphogenesis [GO:0048812]; podosome assembly [GO:0071800]; positive regulation of axon extension [GO:0045773]; positive regulation of dendritic spine morphogenesis [GO:0061003]; postsynaptic actin cytoskeleton organization [GO:0098974]; regulation of actin filament polymerization [GO:0030833]; synapse assembly [GO:0007416] GO:0000139; GO:0001726; GO:0002102; GO:0002250; GO:0005769; GO:0005829; GO:0006897; GO:0007416; GO:0014069; GO:0030027; GO:0030425; GO:0030427; GO:0030665; GO:0030833; GO:0030864; GO:0043204; GO:0045211; GO:0045773; GO:0048812; GO:0051015; GO:0061003; GO:0070161; GO:0071800; GO:0098974 43995 XM_029353836.2 6261 5764 4404 7754 7477 A6H7G2 2.67e-22 Drebrin-like protein Bos taurus (Bovine) adaptive immune response [GO:0002250]; endocytosis [GO:0006897]; neuron projection morphogenesis [GO:0048812]; podosome assembly [GO:0071800]; positive regulation of axon extension [GO:0045773]; positive regulation of dendritic spine morphogenesis [GO:0061003]; postsynaptic actin cytoskeleton organization [GO:0098974]; regulation of actin filament polymerization [GO:0030833]; synapse assembly [GO:0007416] GO:0000139; GO:0001726; GO:0002102; GO:0002250; GO:0005769; GO:0005829; GO:0006897; GO:0007416; GO:0014069; GO:0030027; GO:0030425; GO:0030427; GO:0030665; GO:0030833; GO:0030864; GO:0043204; GO:0045211; GO:0045773; GO:0048812; GO:0051015; GO:0061003; GO:0070161; GO:0071800; GO:0098974 43996 XM_029356038.2 56 31 0 20 55 NA NA NA NA NA NA 43997 XM_029346208.2 43 78 32 66 37 P0CT39 2.28e-80 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 43998 XM_044312969.1 308 261 215 203 269 Q06AA5 2.07e-36 Tetraspanin-9 (Tspan-9) Sus scrofa (Pig) NA GO:0005886 43999 XM_029338089.2 182 100 144 471 131 O80668 2.97e-26 Amino acid transporter AVT1A (AtAvt1A) Arabidopsis thaliana (Mouse-ear cress) amino acid transmembrane transport [GO:0003333] GO:0000325; GO:0003333; GO:0015171; GO:0016020 44000 XM_029332826.2 54 60 35 110 53 NA NA NA NA NA NA 44001 XM_029356995.2 894 1053 761 2239 1311 Q8C9W3 4.06e-97 A disintegrin and metalloproteinase with thrombospondin motifs 2 (ADAM-TS 2) (ADAM-TS2) (ADAMTS-2) (EC 3.4.24.14) (Procollagen I N-proteinase) (PC I-NP) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen N-endopeptidase) (pNPI) Mus musculus (Mouse) collagen catabolic process [GO:0030574]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; lung development [GO:0030324]; protein processing [GO:0016485]; skin development [GO:0043588]; spermatogenesis [GO:0007283] GO:0004222; GO:0005576; GO:0007283; GO:0008233; GO:0008270; GO:0016485; GO:0030198; GO:0030199; GO:0030324; GO:0030574; GO:0031012; GO:0043588; GO:0062023 44002 XM_029356995.2 894 1053 761 2239 1311 Q8C9W3 9.38e-43 A disintegrin and metalloproteinase with thrombospondin motifs 2 (ADAM-TS 2) (ADAM-TS2) (ADAMTS-2) (EC 3.4.24.14) (Procollagen I N-proteinase) (PC I-NP) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen N-endopeptidase) (pNPI) Mus musculus (Mouse) collagen catabolic process [GO:0030574]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; lung development [GO:0030324]; protein processing [GO:0016485]; skin development [GO:0043588]; spermatogenesis [GO:0007283] GO:0004222; GO:0005576; GO:0007283; GO:0008233; GO:0008270; GO:0016485; GO:0030198; GO:0030199; GO:0030324; GO:0030574; GO:0031012; GO:0043588; GO:0062023 44003 XM_029341701.2 14 21 3 50 37 A0A0C2SRU0 1.52e-77 Decarboxylase iboD (EC 4.1.1.-) (Ibotenic acid biosynthesis cluster protein D) Amanita muscaria (strain Koide BX008) phospholipid biosynthetic process [GO:0008654] GO:0004609; GO:0008654 44004 XM_044326717.1 528 718 355 396 429 Q8IXL7 5.43e-54 Methionine-R-sulfoxide reductase B3 (MsrB3) (EC 1.8.4.12) (EC 1.8.4.14) Homo sapiens (Human) protein repair [GO:0030091]; response to oxidative stress [GO:0006979] GO:0005737; GO:0005739; GO:0005783; GO:0005829; GO:0006979; GO:0008270; GO:0030091; GO:0033743; GO:0033745 44005 XM_044317835.1 6 1 14 20 20 NA NA NA NA NA NA 44006 XM_044311993.1 9 4 0 0 13 NA NA NA NA NA NA 44007 XM_044320096.1 9 4 10 18 61 NA NA NA NA NA NA 44008 XM_044320440.1 3 18 3 9 8 NA NA NA NA NA NA 44009 XM_029352621.2 16 0 0 138 153 Q9YGL3 2.29e-54 Nuclear receptor subfamily 2 group E member 1 (Nuclear receptor TLX) (Protein tailless homolog) (Tll) Oryzias latipes (Japanese rice fish) (Japanese killifish) anatomical structure development [GO:0048856]; cell differentiation [GO:0030154]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000978; GO:0004879; GO:0005634; GO:0006357; GO:0008270; GO:0030154; GO:0048856 44010 XM_044320744.1 0 0 3 4 6 NA NA NA NA NA NA 44011 XM_044328470.1 0 0 0 0 44 Q9EQC4 2.39e-70 Elongation of very long chain fatty acids protein 4 (EC 2.3.1.199) (3-keto acyl-CoA synthase Elovl4) (ELOVL fatty acid elongase 4) (ELOVL FA elongase 4) (Very long chain 3-ketoacyl-CoA synthase 4) (Very long chain 3-oxoacyl-CoA synthase 4) Mus musculus (Mouse) fatty acid elongation, monounsaturated fatty acid [GO:0034625]; fatty acid elongation, polyunsaturated fatty acid [GO:0034626]; fatty acid elongation, saturated fatty acid [GO:0019367]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; sphingolipid biosynthetic process [GO:0030148]; unsaturated fatty acid biosynthetic process [GO:0006636]; very long-chain fatty acid biosynthetic process [GO:0042761] GO:0005783; GO:0005789; GO:0006636; GO:0009922; GO:0019367; GO:0030148; GO:0034625; GO:0034626; GO:0035338; GO:0042761; GO:0102756 44012 XM_044321727.1 15 31 0 25 6 NA NA NA NA NA NA 44013 XM_044323597.1 47 45 4 66 37 NA NA NA NA NA NA 44014 XM_044312131.1 41 53 87 367 114 Q80XJ3 7.09e-122 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 44015 XM_044312131.1 41 53 87 367 114 Q80XJ3 5.86e-98 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 44016 XM_044312131.1 41 53 87 367 114 Q80XJ3 8.17e-95 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 44017 XM_044312131.1 41 53 87 367 114 Q80XJ3 1.64e-89 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 44018 XM_044312131.1 41 53 87 367 114 Q80XJ3 2.32e-88 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 44019 XM_044312131.1 41 53 87 367 114 Q80XJ3 1.31e-87 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 44020 XM_044312131.1 41 53 87 367 114 Q80XJ3 2.63e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 44021 XM_044328483.1 46 1 29 97 114 NA NA NA NA NA NA 44022 XR_006392387.1 0 2 0 0 8 NA NA NA NA NA NA 44023 XM_044321199.1 523 336 304 548 733 Q498H0 0 Sister chromatid cohesion protein PDS5 homolog B-A (Androgen-induced proliferation inhibitor A) Xenopus laevis (African clawed frog) cell division [GO:0051301]; mitotic sister chromatid cohesion [GO:0007064]; negative regulation of cell population proliferation [GO:0008285] GO:0003677; GO:0005634; GO:0007064; GO:0008285; GO:0051301 44024 XR_006395840.1 206 155 147 120 180 NA NA NA NA NA NA 44025 XM_044323065.1 43 51 8 22 46 NA NA NA NA NA NA 44026 XM_044324152.1 4 3 11 4 95 NA NA NA NA NA NA 44027 XM_044323458.1 149 215 179 200 112 NA NA NA NA NA NA 44028 XM_029323650.2 1619 3384 1096 3184 2775 O88446 2.07e-66 Solute carrier family 22 member 3 (Organic cation transporter 3) Rattus norvegicus (Rat) cation transmembrane transport [GO:0098655]; dopamine transport [GO:0015872]; dopamine uptake [GO:0090494]; epinephrine uptake [GO:0051625]; establishment of localization in cell [GO:0051649]; histamine transport [GO:0051608]; histamine uptake [GO:0051615]; monoamine transport [GO:0015844]; monocarboxylic acid transport [GO:0015718]; neurotransmitter transport [GO:0006836]; norepinephrine uptake [GO:0051620]; organic anion transport [GO:0015711]; organic cation transport [GO:0015695]; organic hydroxy compound transport [GO:0015850]; quaternary ammonium group transport [GO:0015697]; regulation of appetite [GO:0032098]; serotonin transport [GO:0006837]; serotonin uptake [GO:0051610]; spermidine transport [GO:0015848]; toxin transport [GO:1901998]; xenobiotic transport [GO:0042908] GO:0005326; GO:0005330; GO:0005886; GO:0006836; GO:0006837; GO:0008504; GO:0008514; GO:0015101; GO:0015606; GO:0015651; GO:0015695; GO:0015697; GO:0015711; GO:0015718; GO:0015844; GO:0015848; GO:0015850; GO:0015872; GO:0019534; GO:0022857; GO:0032098; GO:0042908; GO:0043025; GO:0051608; GO:0051610; GO:0051615; GO:0051620; GO:0051625; GO:0051649; GO:0090494; GO:0098655; GO:0098793; GO:1901998 44029 XM_044315206.1 0 0 6 0 0 NA NA NA NA NA NA 44030 XM_044326801.1 85 26 13 64 50 P04323 3.19e-69 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 44031 XM_029353661.2 0 0 71 0 0 P25931 1.56e-23 RYamide receptor (Neuropeptide Y-like receptor) (NPY-R) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218] GO:0001653; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0016020 44032 XM_029328808.2 199 31 55 103 46 P36366 2.58e-132 Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.-) (Dimethylaniline oxidase 2) (FMO 1B1) (Pulmonary flavin-containing monooxygenase 2) (FMO 2) Cavia porcellus (Guinea pig) NADPH oxidation [GO:0070995] GO:0004499; GO:0005789; GO:0016020; GO:0047822; GO:0050660; GO:0050661; GO:0070995 44033 XM_029336573.2 2602 1368 892 1302 594 NA NA NA NA NA NA 44034 XM_029355713.2 30 27 43 12 84 Q0IH87 6.86e-63 Paired box protein Pax-3-B (xPax3-B) (Paired-domain transcription factor Pax3-B) Xenopus laevis (African clawed frog) fibroblast growth factor receptor signaling pathway [GO:0008543]; hatching gland development [GO:0048785]; nervous system development [GO:0007399]; neural crest cell fate commitment [GO:0014034]; neural crest formation [GO:0014029]; positive regulation of DNA-templated transcription [GO:0045893]; Wnt signaling pathway [GO:0016055] GO:0000981; GO:0003677; GO:0005634; GO:0007399; GO:0008543; GO:0014029; GO:0014034; GO:0016055; GO:0045893; GO:0048785 44035 XR_006396276.1 206 47 42 116 108 NA NA NA NA NA NA 44036 XM_044323895.1 404 774 1129 146 0 NA NA NA NA NA NA 44037 XM_029342427.2 0 0 0 0 291 Q5AF03 1.16e-29 Glyoxalase 3 (EC 4.2.1.130) (Glutathione-independent glyoxalase) Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243] GO:0005737; GO:0019172; GO:0019243; GO:0030445; GO:0030446; GO:0062040 44038 XM_029344414.2 1025 1202 920 914 1120 C0QT62 8.44e-35 Probable transcriptional regulatory protein PERMA_0079 Persephonella marina (strain DSM 14350 / EX-H1) regulation of DNA-templated transcription [GO:0006355] GO:0003677; GO:0005737; GO:0006355 44039 XR_006394748.1 164 18 49 69 193 NA NA NA NA NA NA 44040 XM_044321516.1 57 140 153 79 168 NA NA NA NA NA NA 44041 XM_044318495.1 1211 894 1294 516 2923 Q9ULT8 0 E3 ubiquitin-protein ligase HECTD1 (EC 2.3.2.26) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1) Homo sapiens (Human) anatomical structure development [GO:0048856]; aorta development [GO:0035904]; heart valve development [GO:0003170]; natural killer cell differentiation [GO:0001779]; negative regulation of protein localization to plasma membrane [GO:1903077]; neural tube closure [GO:0001843]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein localization to plasma membrane [GO:0072659]; protein polyubiquitination [GO:0000209]; spongiotrophoblast differentiation [GO:0060708]; trophoblast giant cell differentiation [GO:0060707]; ventricular septum development [GO:0003281] GO:0000209; GO:0001779; GO:0001843; GO:0003170; GO:0003281; GO:0016607; GO:0032436; GO:0035904; GO:0043161; GO:0046872; GO:0048856; GO:0051865; GO:0060707; GO:0060708; GO:0061630; GO:0070534; GO:0072659; GO:1903077 44042 XM_044318495.1 1211 894 1294 516 2923 Q9ULT8 2.1e-164 E3 ubiquitin-protein ligase HECTD1 (EC 2.3.2.26) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1) Homo sapiens (Human) anatomical structure development [GO:0048856]; aorta development [GO:0035904]; heart valve development [GO:0003170]; natural killer cell differentiation [GO:0001779]; negative regulation of protein localization to plasma membrane [GO:1903077]; neural tube closure [GO:0001843]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein localization to plasma membrane [GO:0072659]; protein polyubiquitination [GO:0000209]; spongiotrophoblast differentiation [GO:0060708]; trophoblast giant cell differentiation [GO:0060707]; ventricular septum development [GO:0003281] GO:0000209; GO:0001779; GO:0001843; GO:0003170; GO:0003281; GO:0016607; GO:0032436; GO:0035904; GO:0043161; GO:0046872; GO:0048856; GO:0051865; GO:0060707; GO:0060708; GO:0061630; GO:0070534; GO:0072659; GO:1903077 44043 XM_044318495.1 1211 894 1294 516 2923 Q9ULT8 2.5e-103 E3 ubiquitin-protein ligase HECTD1 (EC 2.3.2.26) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1) Homo sapiens (Human) anatomical structure development [GO:0048856]; aorta development [GO:0035904]; heart valve development [GO:0003170]; natural killer cell differentiation [GO:0001779]; negative regulation of protein localization to plasma membrane [GO:1903077]; neural tube closure [GO:0001843]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein localization to plasma membrane [GO:0072659]; protein polyubiquitination [GO:0000209]; spongiotrophoblast differentiation [GO:0060708]; trophoblast giant cell differentiation [GO:0060707]; ventricular septum development [GO:0003281] GO:0000209; GO:0001779; GO:0001843; GO:0003170; GO:0003281; GO:0016607; GO:0032436; GO:0035904; GO:0043161; GO:0046872; GO:0048856; GO:0051865; GO:0060707; GO:0060708; GO:0061630; GO:0070534; GO:0072659; GO:1903077 44044 XM_029346913.2 838 421 621 731 1503 Q9WUU9 4.74e-131 Germinal-center associated nuclear protein (GANP) (EC 2.3.1.48) (GC-associated DNA primase) Mus musculus (Mouse) mRNA export from nucleus [GO:0006406]; nucleosome organization [GO:0034728]; poly(A)+ mRNA export from nucleus [GO:0016973]; protein transport [GO:0015031]; somatic hypermutation of immunoglobulin genes [GO:0016446] GO:0003676; GO:0003682; GO:0004402; GO:0005634; GO:0005654; GO:0005694; GO:0005737; GO:0005829; GO:0006406; GO:0010484; GO:0015031; GO:0016446; GO:0016973; GO:0031965; GO:0034728; GO:0042393; GO:0044615; GO:0070390 44045 XM_029346913.2 838 421 621 731 1503 Q9WUU9 7.24e-27 Germinal-center associated nuclear protein (GANP) (EC 2.3.1.48) (GC-associated DNA primase) Mus musculus (Mouse) mRNA export from nucleus [GO:0006406]; nucleosome organization [GO:0034728]; poly(A)+ mRNA export from nucleus [GO:0016973]; protein transport [GO:0015031]; somatic hypermutation of immunoglobulin genes [GO:0016446] GO:0003676; GO:0003682; GO:0004402; GO:0005634; GO:0005654; GO:0005694; GO:0005737; GO:0005829; GO:0006406; GO:0010484; GO:0015031; GO:0016446; GO:0016973; GO:0031965; GO:0034728; GO:0042393; GO:0044615; GO:0070390 44046 XM_044328911.1 174 247 578 129 844 NA NA NA NA NA NA 44047 XM_029323784.2 225 0 0 0 99 Q99JW2 1.71e-168 Aminoacylase-1 (ACY-1) (EC 3.5.1.14) (N-acyl-L-amino-acid amidohydrolase) Mus musculus (Mouse) amino acid metabolic process [GO:0006520] GO:0004046; GO:0005737; GO:0006520; GO:0042802; GO:0046872; GO:0070062 44048 XM_029355599.2 565 36 76 366 415 O15439 0 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 44049 XM_044319136.1 0 289 328 0 0 NA NA NA NA NA NA 44050 XM_044311435.1 48 424 3 8 99 NA NA NA NA NA NA 44051 XM_044314369.1 93 4 2 34 30 NA NA NA NA NA NA 44052 XM_029346661.2 1040 1262 834 952 1032 NA NA NA NA NA NA 44053 XM_029324731.2 11 11 6 16 18 Q68F72 8.02e-87 Solute carrier family 15 member 4 Xenopus laevis (African clawed frog) dipeptide import across plasma membrane [GO:0140206]; innate immune response [GO:0045087]; mast cell homeostasis [GO:0033023]; peptidoglycan transport [GO:0015835]; positive regulation of innate immune response [GO:0045089]; positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [GO:0070430]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of toll-like receptor 7 signaling pathway [GO:0034157]; positive regulation of toll-like receptor 8 signaling pathway [GO:0034161]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; protein transport [GO:0015031]; regulation of isotype switching to IgG isotypes [GO:0048302]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424] GO:0005290; GO:0005765; GO:0015031; GO:0015333; GO:0015647; GO:0015835; GO:0031901; GO:0033023; GO:0034157; GO:0034161; GO:0034165; GO:0036020; GO:0045087; GO:0045089; GO:0048302; GO:0070424; GO:0070430; GO:0070434; GO:0071916; GO:0140206 44054 XM_044322734.1 4 572 4 3 585 NA NA NA NA NA NA 44055 XM_044315018.1 9 14 5 26 5 NA NA NA NA NA NA 44056 XM_044314667.1 13 20 30 82 155 NA NA NA NA NA NA 44057 XM_029341961.2 699 100 57 176 142 P98070 7.23e-21 Bone morphogenetic protein 1 (BMP-1) (EC 3.4.24.-) Xenopus laevis (African clawed frog) cartilage development [GO:0051216]; cell differentiation [GO:0030154]; ossification [GO:0001503]; proteolysis [GO:0006508] GO:0001503; GO:0004222; GO:0005125; GO:0005509; GO:0005615; GO:0005794; GO:0006508; GO:0008083; GO:0008270; GO:0030154; GO:0051216 44058 XM_029353851.2 22 3 25 30 61 Q8BHB0 1.5e-36 Nucleotide-binding oligomerization domain-containing protein 1 (Caspase recruitment domain-containing protein 4) Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cellular response to muramyl dipeptide [GO:0071225]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; ERK1 and ERK2 cascade [GO:0070371]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of cell death [GO:0010942]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of xenophagy [GO:1904417]; regulation of apoptotic process [GO:0042981]; stress-activated MAPK cascade [GO:0051403]; xenophagy [GO:0098792] GO:0002221; GO:0002606; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006915; GO:0006919; GO:0007249; GO:0007254; GO:0010942; GO:0016045; GO:0016323; GO:0016324; GO:0032731; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0035556; GO:0038187; GO:0042742; GO:0042802; GO:0042803; GO:0042981; GO:0043123; GO:0043280; GO:0044877; GO:0045087; GO:0045335; GO:0046330; GO:0050700; GO:0050830; GO:0051000; GO:0051092; GO:0051403; GO:0060907; GO:0070371; GO:0070374; GO:0071225; GO:0098792; GO:1901224; GO:1904417 44059 XM_029347545.2 244 251 111 133 254 NA NA NA NA NA NA 44060 XR_006395461.1 55 0 27 0 224 NA NA NA NA NA NA 44061 XM_029340178.2 1531 799 677 975 1263 P08239 0 Guanine nucleotide-binding protein G(o) subunit alpha (GTP-binding protein G39) Bos taurus (Bovine) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; dopamine receptor signaling pathway [GO:0007212] GO:0001664; GO:0003924; GO:0005525; GO:0005834; GO:0007188; GO:0007212; GO:0031683; GO:0031821; GO:0031852; GO:0046872; GO:0051430 44062 XM_044326495.1 8 10 0 0 2 NA NA NA NA NA NA 44063 XM_029343767.2 2126 1789 1336 2096 1957 Q9P2C4 6.49e-142 Transmembrane protein 181 Homo sapiens (Human) NA GO:0015643; GO:0016020 44064 XM_029345163.2 162 90 85 303 118 Q9GZS1 1.04e-48 DNA-directed RNA polymerase I subunit RPA49 (RNA polymerase I subunit A49) (DNA-directed RNA polymerase I subunit E) (RNA polymerase I-associated factor 1) (RNA polymerase I-associated factor 53) Homo sapiens (Human) nucleolar large rRNA transcription by RNA polymerase I [GO:0042790]; RNA polymerase I preinitiation complex assembly [GO:0001188]; transcription elongation by RNA polymerase I [GO:0006362] GO:0001179; GO:0001188; GO:0001650; GO:0003677; GO:0005654; GO:0005730; GO:0005736; GO:0006362; GO:0042790 44065 XM_029343294.2 5217 5443 3788 5955 4460 D3YXS5 0 Kinesin-like protein KIF28 (Kinesin family member 28) (Kinesin-like protein 6) Mus musculus (Mouse) microtubule-based movement [GO:0007018]; mitochondrion organization [GO:0007005]; organelle transport along microtubule [GO:0072384] GO:0003777; GO:0005524; GO:0005871; GO:0005874; GO:0007005; GO:0007018; GO:0008017; GO:0016887; GO:0031966; GO:0072384 44066 XM_029346149.2 184 143 118 199 251 Q6DGZ0 2.96e-57 G patch domain-containing protein 11 (Coiled-coil domain-containing protein 75) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0000776; GO:0003676 44067 XM_029329826.2 75 105 55 97 156 NA NA NA NA NA NA 44068 XM_044328174.1 148 40 65 116 106 P50430 8.21e-133 Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S) Rattus norvegicus (Rat) anterior head development [GO:0097065]; autophagy [GO:0006914]; central nervous system development [GO:0007417]; colon epithelial cell migration [GO:0061580]; dermatan sulfate catabolic process [GO:0030209]; positive regulation of neuron projection development [GO:0010976]; regulation of epithelial cell migration [GO:0010632]; response to estrogen [GO:0043627]; response to methylmercury [GO:0051597]; response to nutrient [GO:0007584]; response to pH [GO:0009268] GO:0003943; GO:0004065; GO:0005739; GO:0005764; GO:0005791; GO:0005794; GO:0006914; GO:0007417; GO:0007584; GO:0008484; GO:0009268; GO:0009986; GO:0010632; GO:0010976; GO:0030209; GO:0043627; GO:0043890; GO:0046872; GO:0051597; GO:0061580; GO:0097065 44069 XM_044319824.1 931 649 621 1055 963 Q6PJI9 0 GATOR complex protein WDR59 (WD repeat-containing protein 59) Homo sapiens (Human) cellular response to amino acid starvation [GO:0034198]; negative regulation of TORC1 signaling [GO:1904262]; positive regulation of TOR signaling [GO:0032008]; positive regulation of TORC1 signaling [GO:1904263] GO:0005765; GO:0005774; GO:0032008; GO:0034198; GO:0035591; GO:0035859; GO:0061700; GO:1904262; GO:1904263 44070 XM_044323800.1 0 1 0 9 27 P15043 2.31e-33 ATP-dependent DNA helicase RecQ (EC 3.6.4.12) Escherichia coli (strain K12) cellular response to DNA damage stimulus [GO:0006974]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; SOS response [GO:0009432] GO:0003677; GO:0003678; GO:0005524; GO:0005694; GO:0005737; GO:0006260; GO:0006281; GO:0006310; GO:0006974; GO:0008094; GO:0008270; GO:0009378; GO:0009432; GO:0016887; GO:0017116; GO:0017117; GO:0030894; GO:0032508; GO:0043138; GO:0043590; GO:0046914 44071 XM_029338536.2 59 59 14 135 104 Q7SXV2 3.31e-49 Zinc finger protein AEBP2 (Adipocyte enhancer-binding protein 2 homolog) (AE-binding protein 2 homolog) Danio rerio (Zebrafish) (Brachydanio rerio) chromatin organization [GO:0006325]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0003677; GO:0006325; GO:0006357; GO:0035098; GO:0046872 44072 XM_044325852.1 21 0 82 0 62 NA NA NA NA NA NA 44073 XM_044322477.1 1379 740 559 1164 892 Q6DID3 5.45e-51 SR-related and CTD-associated factor 8 (RNA-binding motif protein 16) Mus musculus (Mouse) mRNA polyadenylation [GO:0006378]; mRNA processing [GO:0006397]; negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled [GO:2000805]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; termination of RNA polymerase II transcription [GO:0006369]; transcription by RNA polymerase II [GO:0006366] GO:0000993; GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0005737; GO:0005849; GO:0006366; GO:0006369; GO:0006378; GO:0006397; GO:0016363; GO:0019904; GO:0032786; GO:0043175; GO:0070063; GO:1990269; GO:2000805 44074 XM_044322477.1 1379 740 559 1164 892 Q6DID3 5.25e-21 SR-related and CTD-associated factor 8 (RNA-binding motif protein 16) Mus musculus (Mouse) mRNA polyadenylation [GO:0006378]; mRNA processing [GO:0006397]; negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled [GO:2000805]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; termination of RNA polymerase II transcription [GO:0006369]; transcription by RNA polymerase II [GO:0006366] GO:0000993; GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0005737; GO:0005849; GO:0006366; GO:0006369; GO:0006378; GO:0006397; GO:0016363; GO:0019904; GO:0032786; GO:0043175; GO:0070063; GO:1990269; GO:2000805 44075 XM_029349477.2 1591 1475 1173 1580 1725 Q9H1Q7 8.21e-51 PC-esterase domain-containing protein 1A (Protein FAM113A) (Sarcoma antigen NY-SAR-23) Homo sapiens (Human) NA GO:0016740 44076 XM_044323468.1 0 0 4 4 7 NA NA NA NA NA NA 44077 XM_029354739.2 0 84 54 40 134 Q3S8M4 2.53e-86 Elongation of very long chain fatty acids protein 4 (EC 2.3.1.199) (3-keto acyl-CoA synthase ELOVL4) (ELOVL fatty acid elongase 4) (ELOVL FA elongase 4) (Very long chain 3-ketoacyl-CoA synthase 4) (Very long chain 3-oxoacyl-CoA synthase 4) Macaca mulatta (Rhesus macaque) fatty acid elongation, monounsaturated fatty acid [GO:0034625]; fatty acid elongation, polyunsaturated fatty acid [GO:0034626]; fatty acid elongation, saturated fatty acid [GO:0019367]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; sphingolipid biosynthetic process [GO:0030148]; unsaturated fatty acid biosynthetic process [GO:0006636]; very long-chain fatty acid biosynthetic process [GO:0042761] GO:0005783; GO:0005789; GO:0006636; GO:0009922; GO:0019367; GO:0030148; GO:0034625; GO:0034626; GO:0035338; GO:0042761; GO:0102756 44078 XM_029342170.2 55 48 40 64 93 NA NA NA NA NA NA 44079 XR_006391768.1 0 0 0 0 10 NA NA NA NA NA NA 44080 XR_006392660.1 145 150 83 18 83 NA NA NA NA NA NA 44081 XM_029349951.2 0 0 413 0 0 O42097 4.24e-71 Hepatocyte nuclear factor 3-beta (HNF-3-beta) (HNF-3B) (Forkhead box protein A2) (Me-HNF3B) Oryzias latipes (Japanese rice fish) (Japanese killifish) anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; regulation of transcription by RNA polymerase II [GO:0006357]; system development [GO:0048731] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0009653; GO:0019904; GO:0030154; GO:0048731 44082 XM_044321725.1 260 499 300 475 445 NA NA NA NA NA NA 44083 XM_044309767.1 119 339 133 42 373 O88572 0 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 44084 XM_044309767.1 119 339 133 42 373 O88572 9.6e-171 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 44085 XM_044307225.1 1051 1058 253 173 459 NA NA NA NA NA NA 44086 XM_029341419.2 37 40 0 43 42 NA NA NA NA NA NA 44087 XR_006395405.1 0 27 1 2 0 NA NA NA NA NA NA 44088 XM_029337680.2 651 478 382 672 916 P48553 0 Trafficking protein particle complex subunit 10 (Epilepsy holoprosencephaly candidate 1 protein) (EHOC-1) (Protein GT334) (Trafficking protein particle complex subunit TMEM1) (Transport protein particle subunit TMEM1) (TRAPP subunit TMEM1) Homo sapiens (Human) early endosome to Golgi transport [GO:0034498]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; vesicle coating [GO:0006901]; vesicle tethering [GO:0099022] GO:0005737; GO:0005829; GO:0006888; GO:0006891; GO:0006901; GO:0030008; GO:0034498; GO:0099022; GO:1990071 44089 XM_044322025.1 178 432 12 151 43 P09487 6.7e-136 Alkaline phosphatase, tissue-nonspecific isozyme (AP-TNAP) (TNAP) (TNSALP) (EC 3.1.3.1) (Alkaline phosphatase liver/bone/kidney isozyme) (Phosphoamidase) (Phosphocreatine phosphatase) (EC 3.9.1.1) Bos taurus (Bovine) biomineral tissue development [GO:0031214]; bone mineralization [GO:0030282]; calcium ion homeostasis [GO:0055074]; cellular homeostasis [GO:0019725]; cellular response to organic cyclic compound [GO:0071407]; dephosphorylation [GO:0016311]; developmental process involved in reproduction [GO:0003006]; endochondral ossification [GO:0001958]; multicellular organism aging [GO:0010259]; phosphate ion homeostasis [GO:0055062]; positive regulation of cold-induced thermogenesis [GO:0120162]; pyridoxal phosphate metabolic process [GO:0042822]; response to antibiotic [GO:0046677]; response to sodium phosphate [GO:1904383]; response to vitamin B6 [GO:0034516]; response to vitamin D [GO:0033280] GO:0001958; GO:0003006; GO:0004035; GO:0004427; GO:0005509; GO:0005758; GO:0005886; GO:0010259; GO:0016311; GO:0016462; GO:0016887; GO:0019725; GO:0030282; GO:0031012; GO:0031214; GO:0031966; GO:0033280; GO:0033883; GO:0034516; GO:0042822; GO:0043262; GO:0046677; GO:0050187; GO:0052732; GO:0055062; GO:0055074; GO:0065010; GO:0071407; GO:0120162; GO:1904383 44090 XR_006393514.1 203 305 30 0 0 NA NA NA NA NA NA 44091 XM_029337360.2 146 50 11 14 31 NA NA NA NA NA NA 44092 XM_029324026.2 56 8 54 19 16 NA NA NA NA NA NA 44093 XM_029331693.2 895 1045 1034 1068 462 NA NA NA NA NA NA 44094 XM_029353992.2 1 1 6 79 11 NA NA NA NA NA NA 44095 XM_044311041.1 6 0 14 7 1 NA NA NA NA NA NA 44096 XM_044321904.1 314 0 124 719 225 O34363 1.51e-24 Putative L-amino-acid oxidase YobN (EC 1.4.3.2) Bacillus subtilis (strain 168) amino acid catabolic process [GO:0009063] GO:0001716; GO:0009063; GO:0016491; GO:0046592 44097 XM_029343046.2 238 321 78 203 190 Q5E9D6 9.61e-44 Haloacid dehalogenase-like hydrolase domain-containing protein 3 Bos taurus (Bovine) NA GO:0005634 44098 XM_044325393.1 0 27 19 1 39 P07911 8.48e-28 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Homo sapiens (Human) antibacterial innate immune response [GO:0140367]; apoptotic signaling pathway [GO:0097190]; autophagy [GO:0006914]; cellular calcium ion homeostasis [GO:0006874]; cellular chloride ion homeostasis [GO:0030644]; cellular defense response [GO:0006968]; cellular phosphate ion homeostasis [GO:0030643]; cellular response to unfolded protein [GO:0034620]; cellular sodium ion homeostasis [GO:0006883]; chaperone-mediated protein folding [GO:0061077]; citric acid secretion [GO:0046720]; collecting duct development [GO:0072044]; connective tissue replacement [GO:0097709]; creatinine homeostasis [GO:0097273]; defense response to Gram-negative bacterium [GO:0050829]; endoplasmic reticulum organization [GO:0007029]; glomerular filtration [GO:0003094]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; juxtaglomerular apparatus development [GO:0072051]; leukocyte cell-cell adhesion [GO:0007159]; lipid metabolic process [GO:0006629]; metanephric ascending thin limb development [GO:0072218]; metanephric distal convoluted tubule development [GO:0072221]; metanephric thick ascending limb development [GO:0072233]; micturition [GO:0060073]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell population proliferation [GO:0008285]; neutrophil migration [GO:1990266]; organ or tissue specific immune response [GO:0002251]; peptidyl-threonine phosphorylation [GO:0018107]; potassium ion homeostasis [GO:0055075]; protein localization to vacuole [GO:0072665]; protein transport into plasma membrane raft [GO:0044861]; regulation of blood pressure [GO:0008217]; regulation of protein transport [GO:0051223]; regulation of urine volume [GO:0035809]; renal sodium ion absorption [GO:0070294]; renal urate salt excretion [GO:0097744]; renal water homeostasis [GO:0003091]; response to lipopolysaccharide [GO:0032496]; response to water deprivation [GO:0009414]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; ubiquitin-dependent ERAD pathway [GO:0030433]; urate transport [GO:0015747]; urea transmembrane transport [GO:0071918] GO:0000922; GO:0002251; GO:0003091; GO:0003094; GO:0005201; GO:0005509; GO:0005615; GO:0005783; GO:0005796; GO:0005929; GO:0006629; GO:0006874; GO:0006883; GO:0006914; GO:0006954; GO:0006968; GO:0007029; GO:0007157; GO:0007159; GO:0008217; GO:0008285; GO:0008380; GO:0009410; GO:0009414; GO:0009986; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0018107; GO:0019864; GO:0019898; GO:0030433; GO:0030643; GO:0030644; GO:0032496; GO:0033209; GO:0033555; GO:0034620; GO:0035809; GO:0044861; GO:0046720; GO:0050829; GO:0051223; GO:0055075; GO:0060073; GO:0060170; GO:0061077; GO:0070062; GO:0070294; GO:0071918; GO:0072044; GO:0072051; GO:0072218; GO:0072221; GO:0072233; GO:0072665; GO:0097190; GO:0097273; GO:0097709; GO:0097744; GO:0140367; GO:1990266 44099 XR_006394258.1 11 4 43 9 189 NA NA NA NA NA NA 44100 XM_029349205.2 336 237 350 479 512 Q61749 1.04e-156 Translation initiation factor eIF-2B subunit delta (eIF-2B GDP-GTP exchange factor subunit delta) Mus musculus (Mouse) myelination [GO:0042552]; negative regulation of guanyl-nucleotide exchange factor activity [GO:1905098]; oligodendrocyte development [GO:0014003]; ovarian follicle development [GO:0001541]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to peptide hormone [GO:0043434]; T cell receptor signaling pathway [GO:0050852]; translational initiation [GO:0006413] GO:0001541; GO:0003743; GO:0005085; GO:0005737; GO:0005851; GO:0006413; GO:0009408; GO:0009749; GO:0014003; GO:0031369; GO:0042552; GO:0043434; GO:0050852; GO:1905098 44101 XR_006394371.1 45 1 11 23 14 NA NA NA NA NA NA 44102 XM_044322292.1 0 0 6 0 11 NA NA NA NA NA NA 44103 XM_044312584.1 60 26 39 74 63 Q5R7P4 0 Beta-galactosidase (EC 3.2.1.23) (Acid beta-galactosidase) (Lactase) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) carbohydrate metabolic process [GO:0005975] GO:0004565; GO:0005764; GO:0005975 44104 XM_044320550.1 798 2920 2017 514 1838 NA NA NA NA NA NA 44105 XM_044315985.1 0 59 0 0 306 A3KN83 0 Protein strawberry notch homolog 1 (Monocyte protein 3) (MOP-3) Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355]; regulation of response to stimulus [GO:0048583] GO:0005634; GO:0006355; GO:0031490; GO:0042393; GO:0048583 44106 XR_003827815.2 62 21 28 44 24 Q5RAZ4 0 ATP-dependent RNA helicase DHX15 (EC 3.6.4.13) (DEAH box protein 15) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) antiviral innate immune response [GO:0140374]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; mRNA processing [GO:0006397]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; RNA splicing [GO:0008380] GO:0003724; GO:0003725; GO:0005524; GO:0005689; GO:0005730; GO:0006397; GO:0008380; GO:0016607; GO:0016887; GO:0042742; GO:0043123; GO:0051607; GO:0071008; GO:0140374 44107 XM_044321514.1 768 695 404 1112 565 NA NA NA NA NA NA 44108 XM_029337920.2 141 60 56 76 60 Q4ZHW1 7.84e-51 Pancreas transcription factor 1 subunit alpha (Pancreas-specific transcription factor 1a) (Transcription factor Ptf1a/p48) Xenopus laevis (African clawed frog) exocrine pancreas development [GO:0031017]; generation of neurons [GO:0048699]; hindbrain development [GO:0030902]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA-templated transcription [GO:0006355]; retinoic acid receptor signaling pathway [GO:0048384]; tissue development [GO:0009888] GO:0003677; GO:0005634; GO:0005667; GO:0005737; GO:0006355; GO:0009888; GO:0030902; GO:0031017; GO:0045893; GO:0046983; GO:0048384; GO:0048699 44109 XM_029326668.2 1011 855 558 756 740 Q9Z136 1.07e-58 Hamartin (Tuberous sclerosis 1 protein homolog) Rattus norvegicus (Rat) activation of GTPase activity [GO:0090630]; adaptive immune response [GO:0002250]; adult locomotory behavior [GO:0008344]; associative learning [GO:0008306]; cardiac muscle cell differentiation [GO:0055007]; cell population proliferation [GO:0008283]; cell projection organization [GO:0030030]; cell-matrix adhesion [GO:0007160]; cellular response to oxygen-glucose deprivation [GO:0090650]; cerebral cortex development [GO:0021987]; glucose import [GO:0046323]; hippocampus development [GO:0021766]; kidney development [GO:0001822]; memory T cell differentiation [GO:0043379]; myelination [GO:0042552]; negative regulation of ATP-dependent activity [GO:0032780]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of macroautophagy [GO:0016242]; negative regulation of neuron projection development [GO:0010977]; negative regulation of oxidative stress-induced neuron death [GO:1903204]; negative regulation of TOR signaling [GO:0032007]; negative regulation of translation [GO:0017148]; nervous system development [GO:0007399]; neural tube closure [GO:0001843]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of macroautophagy [GO:0016239]; positive regulation of stress fiber assembly [GO:0051496]; potassium ion transport [GO:0006813]; protein stabilization [GO:0050821]; regulation of cell cycle [GO:0051726]; regulation of cell-matrix adhesion [GO:0001952]; regulation of focal adhesion assembly [GO:0051893]; regulation of neuron death [GO:1901214]; regulation of phosphoprotein phosphatase activity [GO:0043666]; regulation of protein kinase activity [GO:0045859]; regulation of stress fiber assembly [GO:0051492]; regulation of translation [GO:0006417]; response to insulin [GO:0032868]; response to nutrient levels [GO:0031667]; response to peptide [GO:1901652]; rRNA export from nucleus [GO:0006407]; synapse organization [GO:0050808] GO:0001822; GO:0001843; GO:0001952; GO:0002250; GO:0005634; GO:0005737; GO:0005811; GO:0005829; GO:0005856; GO:0005884; GO:0005938; GO:0006407; GO:0006417; GO:0006813; GO:0007160; GO:0007399; GO:0008283; GO:0008285; GO:0008306; GO:0008344; GO:0010977; GO:0014069; GO:0016020; GO:0016239; GO:0016242; GO:0017148; GO:0021766; GO:0021987; GO:0030027; GO:0030030; GO:0030426; GO:0030544; GO:0031667; GO:0032007; GO:0032780; GO:0032794; GO:0032868; GO:0032991; GO:0033596; GO:0034260; GO:0042030; GO:0042552; GO:0042995; GO:0043231; GO:0043379; GO:0043666; GO:0044877; GO:0045792; GO:0045859; GO:0046323; GO:0047485; GO:0048471; GO:0050808; GO:0050821; GO:0051087; GO:0051492; GO:0051496; GO:0051726; GO:0051879; GO:0051893; GO:0051894; GO:0055007; GO:0090630; GO:0090650; GO:0101031; GO:1901214; GO:1901652; GO:1903204 44110 XM_029326668.2 1011 855 558 756 740 Q9Z136 3.21e-30 Hamartin (Tuberous sclerosis 1 protein homolog) Rattus norvegicus (Rat) activation of GTPase activity [GO:0090630]; adaptive immune response [GO:0002250]; adult locomotory behavior [GO:0008344]; associative learning [GO:0008306]; cardiac muscle cell differentiation [GO:0055007]; cell population proliferation [GO:0008283]; cell projection organization [GO:0030030]; cell-matrix adhesion [GO:0007160]; cellular response to oxygen-glucose deprivation [GO:0090650]; cerebral cortex development [GO:0021987]; glucose import [GO:0046323]; hippocampus development [GO:0021766]; kidney development [GO:0001822]; memory T cell differentiation [GO:0043379]; myelination [GO:0042552]; negative regulation of ATP-dependent activity [GO:0032780]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of macroautophagy [GO:0016242]; negative regulation of neuron projection development [GO:0010977]; negative regulation of oxidative stress-induced neuron death [GO:1903204]; negative regulation of TOR signaling [GO:0032007]; negative regulation of translation [GO:0017148]; nervous system development [GO:0007399]; neural tube closure [GO:0001843]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of macroautophagy [GO:0016239]; positive regulation of stress fiber assembly [GO:0051496]; potassium ion transport [GO:0006813]; protein stabilization [GO:0050821]; regulation of cell cycle [GO:0051726]; regulation of cell-matrix adhesion [GO:0001952]; regulation of focal adhesion assembly [GO:0051893]; regulation of neuron death [GO:1901214]; regulation of phosphoprotein phosphatase activity [GO:0043666]; regulation of protein kinase activity [GO:0045859]; regulation of stress fiber assembly [GO:0051492]; regulation of translation [GO:0006417]; response to insulin [GO:0032868]; response to nutrient levels [GO:0031667]; response to peptide [GO:1901652]; rRNA export from nucleus [GO:0006407]; synapse organization [GO:0050808] GO:0001822; GO:0001843; GO:0001952; GO:0002250; GO:0005634; GO:0005737; GO:0005811; GO:0005829; GO:0005856; GO:0005884; GO:0005938; GO:0006407; GO:0006417; GO:0006813; GO:0007160; GO:0007399; GO:0008283; GO:0008285; GO:0008306; GO:0008344; GO:0010977; GO:0014069; GO:0016020; GO:0016239; GO:0016242; GO:0017148; GO:0021766; GO:0021987; GO:0030027; GO:0030030; GO:0030426; GO:0030544; GO:0031667; GO:0032007; GO:0032780; GO:0032794; GO:0032868; GO:0032991; GO:0033596; GO:0034260; GO:0042030; GO:0042552; GO:0042995; GO:0043231; GO:0043379; GO:0043666; GO:0044877; GO:0045792; GO:0045859; GO:0046323; GO:0047485; GO:0048471; GO:0050808; GO:0050821; GO:0051087; GO:0051492; GO:0051496; GO:0051726; GO:0051879; GO:0051893; GO:0051894; GO:0055007; GO:0090630; GO:0090650; GO:0101031; GO:1901214; GO:1901652; GO:1903204 44111 XM_044315686.1 0 0 0 12 0 NA NA NA NA NA NA 44112 XM_044306812.1 35 9 12 28 5 NA NA NA NA NA NA 44113 XM_029352192.2 1479 784 584 1255 1049 Q56UN5 2.81e-100 Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in COPD, protein kinase) (SPS1/STE20-related protein kinase YSK4) Homo sapiens (Human) protein phosphorylation [GO:0006468]; signal transduction [GO:0007165] GO:0004672; GO:0004674; GO:0005524; GO:0006468; GO:0007165; GO:0106310 44114 XR_006393164.1 26 0 0 0 70 NA NA NA NA NA NA 44115 XR_006391570.1 1192 1335 955 1041 745 NA NA NA NA NA NA 44116 XM_044311644.1 36 4 18 855 39 Q9Z2E3 1.48e-28 Serine/threonine-protein kinase/endoribonuclease IRE2 (Endoplasmic reticulum-to-nucleus signaling 2) (Inositol-requiring protein 2) (Ire1-beta) (IRE1b) (mIre1) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)] Mus musculus (Mouse) apoptotic chromosome condensation [GO:0030263]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; IRE1-mediated unfolded protein response [GO:0036498]; mRNA processing [GO:0006397]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of JUN kinase activity [GO:0043507]; protein phosphorylation [GO:0006468]; regulation of DNA-templated transcription [GO:0006355]; response to endoplasmic reticulum stress [GO:0034976]; rRNA catabolic process [GO:0016075] GO:0000287; GO:0004519; GO:0004521; GO:0004674; GO:0005524; GO:0005783; GO:0005829; GO:0006355; GO:0006397; GO:0006468; GO:0016075; GO:0030263; GO:0034976; GO:0036498; GO:0043507; GO:0044322; GO:0045892; GO:0051082; GO:0070059; GO:0106310; GO:1990604 44117 XM_044327687.1 1 0 6 0 6 NA NA NA NA NA NA 44118 XM_044307478.1 9 0 1 3 0 NA NA NA NA NA NA 44119 XR_003828069.2 111 100 96 112 231 NA NA NA NA NA NA 44120 XM_029358156.2 687 432 340 493 507 Q9CZJ1 1.98e-54 Probable U3 small nucleolar RNA-associated protein 11 (U3 snoRNA-associated protein 11) (UTP11-like protein) Mus musculus (Mouse) nervous system development [GO:0007399]; positive regulation of apoptotic process [GO:0043065]; rRNA processing [GO:0006364] GO:0005615; GO:0005730; GO:0005737; GO:0006364; GO:0007399; GO:0032040; GO:0043065 44121 XM_029354264.2 132 96 32 156 53 Q4V348 3.16e-118 Zinc finger protein 658B Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 44122 XM_029354264.2 132 96 32 156 53 Q4V348 1.31e-110 Zinc finger protein 658B Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 44123 XM_029354264.2 132 96 32 156 53 Q4V348 1.98e-108 Zinc finger protein 658B Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 44124 XM_029354264.2 132 96 32 156 53 Q4V348 2.94e-106 Zinc finger protein 658B Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 44125 XM_029354264.2 132 96 32 156 53 Q4V348 1.59e-87 Zinc finger protein 658B Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 44126 XM_029354264.2 132 96 32 156 53 Q4V348 1.73e-77 Zinc finger protein 658B Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 44127 XM_029357768.2 310 339 189 206 294 Q0P5A6 4.03e-93 26S proteasome non-ATPase regulatory subunit 5 Bos taurus (Bovine) proteasome assembly [GO:0043248] GO:0022624; GO:0043248 44128 XM_044310420.1 72 14 0 0 0 NA NA NA NA NA NA 44129 XR_006395848.1 365 300 427 23 297 NA NA NA NA NA NA 44130 XM_029333840.2 635 407 333 463 235 NA NA NA NA NA NA 44131 XM_029323621.2 393 215 149 282 273 NA NA NA NA NA NA 44132 XM_029333278.2 0 40 0 0 0 Q16281 0 Cyclic nucleotide-gated cation channel alpha-3 (Cone photoreceptor cGMP-gated channel subunit alpha) (Cyclic nucleotide-gated channel alpha-3) (CNG channel alpha-3) (CNG-3) (CNG3) Homo sapiens (Human) cation transmembrane transport [GO:0098655]; cation transport [GO:0006812]; inorganic cation import across plasma membrane [GO:0098659]; response to cAMP [GO:0051591]; response to corticosteroid [GO:0031960]; response to magnesium ion [GO:0032026]; signal transduction [GO:0007165]; visual perception [GO:0007601] GO:0005222; GO:0005223; GO:0005737; GO:0005886; GO:0006812; GO:0007165; GO:0007601; GO:0008022; GO:0015276; GO:0017071; GO:0030425; GO:0030553; GO:0031960; GO:0032026; GO:0043194; GO:0043204; GO:0044877; GO:0051591; GO:0097386; GO:0098655; GO:0098659; GO:1902495 44133 XM_029340645.2 3655 5463 3225 3403 2629 NA NA NA NA NA NA 44134 XM_044317381.1 0 0 6 0 0 Q96AY4 1.12e-47 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44135 XM_044317381.1 0 0 6 0 0 Q96AY4 5.83e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44136 XM_044317381.1 0 0 6 0 0 Q96AY4 1.29e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44137 XM_044317381.1 0 0 6 0 0 Q96AY4 9.39e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44138 XM_044317381.1 0 0 6 0 0 Q96AY4 8.22e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44139 XM_044317381.1 0 0 6 0 0 Q96AY4 9.26e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44140 XM_044317381.1 0 0 6 0 0 Q96AY4 1.01e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44141 XM_044317381.1 0 0 6 0 0 Q96AY4 2.26e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44142 XM_044317381.1 0 0 6 0 0 Q96AY4 1.73e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44143 XM_029345886.2 393 343 209 376 178 NA NA NA NA NA NA 44144 XM_044319516.1 95 38 53 228 138 NA NA NA NA NA NA 44145 XR_006397497.1 151 109 25 89 186 NA NA NA NA NA NA 44146 XR_006394030.1 148 65 41 119 101 NA NA NA NA NA NA 44147 XM_044310810.1 28 39 36 57 40 NA NA NA NA NA NA 44148 XM_044315893.1 5 1 1 15 12 NA NA NA NA NA NA 44149 XM_029344128.2 0 0 0 24 0 NA NA NA NA NA NA 44150 XR_003825254.2 47 15 29 15 31 NA NA NA NA NA NA 44151 XM_044326952.1 41 3 96 6 360 NA NA NA NA NA NA 44152 XM_029353395.2 0 0 0 3 67 NA NA NA NA NA NA 44153 XM_029329170.2 700 640 349 799 584 Q8BZM1 1.05e-55 Glomulin (FK506-binding protein-associated protein) (FAP) (FKBP-associated protein) Mus musculus (Mouse) cell surface receptor signaling pathway [GO:0007166]; circulatory system development [GO:0072359]; epigenetic regulation of gene expression [GO:0040029]; muscle cell differentiation [GO:0042692]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of T cell proliferation [GO:0042130]; neural tube closure [GO:0001843]; positive regulation of cytokine production [GO:0001819]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of phosphorylation [GO:0042327]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]; vasculogenesis [GO:0001570] GO:0001570; GO:0001819; GO:0001843; GO:0005102; GO:0005171; GO:0005737; GO:0007166; GO:0008285; GO:0031461; GO:0031462; GO:0031463; GO:0031464; GO:0031625; GO:0032434; GO:0032743; GO:0040029; GO:0042130; GO:0042327; GO:0042692; GO:0055105; GO:0072359 44154 XM_029330303.2 6154 3998 3265 4879 2087 Q9IA88 1.44e-155 Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2) Gallus gallus (Chicken) intracellular signal transduction [GO:0035556]; microtubule cytoskeleton organization [GO:0000226]; protein phosphorylation [GO:0006468]; regulation of insulin receptor signaling pathway [GO:0046626] GO:0000226; GO:0000287; GO:0004674; GO:0005524; GO:0005737; GO:0006468; GO:0035556; GO:0046626; GO:0050321; GO:0106310 44155 XR_006392718.1 1 0 75 8 1 NA NA NA NA NA NA 44156 XM_029337060.2 23 0 6 29 20 Q8IVH2 2.38e-75 Forkhead box protein P4 (Fork head-related protein-like A) Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000785; GO:0000978; GO:0000981; GO:0001227; GO:0005634; GO:0006357; GO:0046872 44157 XM_044308204.1 320 227 186 253 193 NA NA NA NA NA NA 44158 XM_029332044.2 168 42 58 103 120 NA NA NA NA NA NA 44159 XM_044324338.1 2669 2582 1655 2353 2607 O35075 2.35e-140 Vacuolar protein sorting-associated protein 26C (Down syndrome critical region protein 3 homolog) (Down syndrome critical region protein A homolog) Mus musculus (Mouse) endocytic recycling [GO:0032456]; intracellular protein transport [GO:0006886] GO:0005768; GO:0006886; GO:0032456 44160 XM_029343537.2 635 970 410 764 472 NA NA NA NA NA NA 44161 XM_029356754.2 191 111 90 130 308 Q8NHP1 9.13e-86 Aflatoxin B1 aldehyde reductase member 4 (EC 1.-.-.-) (AFB1 aldehyde reductase 3) (AFB1-AR 3) (Aldoketoreductase 7-like) Homo sapiens (Human) NA GO:0004033; GO:0005737; GO:0005829; GO:0070062 44162 XM_029356754.2 191 111 90 130 308 Q8NHP1 1.44e-44 Aflatoxin B1 aldehyde reductase member 4 (EC 1.-.-.-) (AFB1 aldehyde reductase 3) (AFB1-AR 3) (Aldoketoreductase 7-like) Homo sapiens (Human) NA GO:0004033; GO:0005737; GO:0005829; GO:0070062 44163 XM_044328724.1 530 259 280 1074 636 B0WWP2 1.57e-110 Kelch-like protein diablo Culex quinquefasciatus (Southern house mosquito) (Culex pungens) negative regulation of synaptic assembly at neuromuscular junction [GO:0045886]; protein ubiquitination [GO:0016567] GO:0003779; GO:0016567; GO:0045886 44164 XM_044312183.1 994 774 960 1643 1419 NA NA NA NA NA NA 44165 XM_029339407.2 62 0 0 0 0 NA NA NA NA NA NA 44166 XM_029357500.2 32 0 2 0 0 P23824 2.69e-70 GATA-binding factor 2 (GATA-2) (Transcription factor NF-E1b) Gallus gallus (Chicken) cell fate commitment [GO:0045165]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of angiogenesis [GO:0045766]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000122; GO:0000978; GO:0000981; GO:0001223; GO:0005634; GO:0008270; GO:0045165; GO:0045766; GO:0045944; GO:1902895 44167 XR_006395386.1 550 338 469 387 468 NA NA NA NA NA NA 44168 XM_044315390.1 19 0 7 3 27 Q5R4A0 0 NEDD8-activating enzyme E1 catalytic subunit (EC 6.2.1.64) (NEDD8-activating enzyme E1C) (Ubiquitin-activating enzyme E1C) (Ubiquitin-like modifier-activating enzyme 3) (Ubiquitin-activating enzyme 3) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) endomitotic cell cycle [GO:0007113]; protein neddylation [GO:0045116]; regulation of cell cycle [GO:0051726] GO:0005524; GO:0005634; GO:0007113; GO:0019781; GO:0032991; GO:0042802; GO:0045116; GO:0046982; GO:0051726 44169 XM_029329835.2 447 431 253 330 279 P60899 7.36e-69 DNA-directed RNA polymerase II subunit RPB9 (RNA polymerase II subunit B9) (DNA-directed RNA polymerase II subunit I) (RNA polymerase II 14.5 kDa subunit) (RPB14.5) Sus scrofa (Pig) maintenance of transcriptional fidelity during transcription elongation by RNA polymerase II [GO:0001193]; mRNA cleavage [GO:0006379]; transcription by RNA polymerase II [GO:0006366]; transcription initiation at RNA polymerase II promoter [GO:0006367]; transcription-coupled nucleotide-excision repair [GO:0006283] GO:0001193; GO:0003676; GO:0003899; GO:0005634; GO:0005665; GO:0005730; GO:0006283; GO:0006366; GO:0006367; GO:0006379; GO:0008270 44170 XR_006395737.1 626 369 192 45 306 NA NA NA NA NA NA 44171 XM_029339080.2 2297 2771 2433 5724 4464 B3EWY9 9.62e-119 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 44172 XM_029339080.2 2297 2771 2433 5724 4464 B3EWY9 9.46e-41 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 44173 XM_029339080.2 2297 2771 2433 5724 4464 B3EWY9 6.95e-29 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 44174 XM_044328707.1 52 5 1 24 76 NA NA NA NA NA NA 44175 XM_044321687.1 1067 1320 962 1024 616 Q5RGV1 0 Inosine-5'-monophosphate dehydrogenase 1b (IMP dehydrogenase 1b) (IMPD 1b) (IMPDH 1b) (EC 1.1.1.205) Danio rerio (Zebrafish) (Brachydanio rerio) GMP biosynthetic process [GO:0006177]; GTP biosynthetic process [GO:0006183] GO:0000166; GO:0003938; GO:0005634; GO:0005737; GO:0006177; GO:0006183; GO:0046872 44176 XM_044321024.1 209 154 149 426 237 NA NA NA NA NA NA 44177 XR_006396845.1 2652 2012 1469 3837 3061 NA NA NA NA NA NA 44178 XM_029323646.2 755 687 433 940 941 Q9H3R1 0 Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 4) (NDST-4) (N-heparan sulfate sulfotransferase 4) (N-HSST 4) [Includes: Heparan sulfate N-deacetylase 4 (EC 3.-.-.-); Heparan sulfate N-sulfotransferase 4 (EC 2.8.2.-)] Homo sapiens (Human) heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0015014]; heparin biosynthetic process [GO:0030210] GO:0000139; GO:0005794; GO:0015014; GO:0015016; GO:0019213; GO:0030210; GO:0050119 44179 XM_029356365.2 0 0 62 0 0 P55112 4.81e-37 Zinc metalloproteinase nas-4 (EC 3.4.24.-) (Nematode astacin 4) Caenorhabditis elegans proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0006508; GO:0008270 44180 XM_044308589.1 340 156 408 1025 243 NA NA NA NA NA NA 44181 XM_029340110.2 559 349 281 494 830 Q63185 1.33e-46 Eukaryotic translation initiation factor 2-alpha kinase 1 (EC 2.7.11.1) (Heme-controlled repressor) (HCR) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Hemin-sensitive initiation factor 2-alpha kinase) Rattus norvegicus (Rat) acute inflammatory response [GO:0002526]; establishment of localization in cell [GO:0051649]; HRI-mediated signaling [GO:0140468]; integrated stress response signaling [GO:0140467]; iron ion homeostasis [GO:0055072]; macrophage differentiation [GO:0030225]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of hemoglobin biosynthetic process [GO:0046986]; negative regulation of translation [GO:0017148]; phagocytosis [GO:0006909]; protein autophosphorylation [GO:0046777]; protoporphyrinogen IX metabolic process [GO:0046501]; regulation of eIF2 alpha phosphorylation by heme [GO:0010999]; regulation of hemoglobin biosynthetic process [GO:0046984]; regulation of translation [GO:0006417]; response to iron ion starvation [GO:1990641] GO:0002526; GO:0004672; GO:0004694; GO:0005524; GO:0005737; GO:0006417; GO:0006909; GO:0008285; GO:0010999; GO:0017148; GO:0020037; GO:0030225; GO:0042803; GO:0046501; GO:0046777; GO:0046984; GO:0046986; GO:0051649; GO:0055072; GO:0106310; GO:0140467; GO:0140468; GO:1990641 44182 XM_029335279.2 77 532 168 196 84 Q7ZXT3 3.48e-100 Enhancer of mRNA-decapping protein 4 Xenopus laevis (African clawed frog) deadenylation-independent decapping of nuclear-transcribed mRNA [GO:0031087] GO:0000932; GO:0005634; GO:0031087 44183 XM_029335279.2 77 532 168 196 84 Q7ZXT3 6.47e-63 Enhancer of mRNA-decapping protein 4 Xenopus laevis (African clawed frog) deadenylation-independent decapping of nuclear-transcribed mRNA [GO:0031087] GO:0000932; GO:0005634; GO:0031087 44184 XM_044312655.1 21 18 6 5 22 NA NA NA NA NA NA 44185 XM_044319170.1 21 38 0 105 18 Q80TR1 4.82e-49 Adhesion G protein-coupled receptor L1 (Calcium-independent alpha-latrotoxin receptor 1) (CIRL-1) (Latrophilin-1) (Lectomedin-2) Mus musculus (Mouse) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell surface receptor signaling pathway [GO:0007166]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synapse maturation [GO:0090129] GO:0004930; GO:0005886; GO:0007157; GO:0007166; GO:0007189; GO:0014069; GO:0015643; GO:0016524; GO:0030246; GO:0030424; GO:0030426; GO:0035584; GO:0042734; GO:0043005; GO:0045202; GO:0050839; GO:0051965; GO:0090129; GO:0098978 44186 XM_029342771.2 84 5 82 15 280 Q9GZV8 2.65e-137 PR domain zinc finger protein 14 (EC 2.1.1.-) (PR domain-containing protein 14) Homo sapiens (Human) cell fate specification [GO:0001708]; cell morphogenesis [GO:0000902]; embryo implantation [GO:0007566]; fertilization [GO:0009566]; fibroblast growth factor receptor signaling pathway [GO:0008543]; germ cell development [GO:0007281]; germ-line stem cell population maintenance [GO:0030718]; histone H3-R26 methylation [GO:0034972]; homeostasis of number of cells within a tissue [GO:0048873]; inactivation of paternal X chromosome [GO:0060817]; inner cell mass cell fate commitment [GO:0001827]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of flagellated sperm motility [GO:1902093]; positive regulation of stem cell population maintenance [GO:1902459]; regulation of DNA methylation [GO:0044030]; regulation of gene expression [GO:0010468]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000902; GO:0000977; GO:0001708; GO:0001827; GO:0003723; GO:0005634; GO:0005654; GO:0006357; GO:0007281; GO:0007566; GO:0008168; GO:0008543; GO:0009566; GO:0010468; GO:0030718; GO:0031490; GO:0034972; GO:0040037; GO:0044030; GO:0046872; GO:0048873; GO:0060817; GO:1902093; GO:1902459 44187 XR_006398033.1 0 7 28 4 16 NA NA NA NA NA NA 44188 XM_029335983.2 6 56 0 61 0 O43299 5.57e-85 AP-5 complex subunit zeta-1 (Adaptor-related protein complex 5 zeta subunit) (Zeta5) Homo sapiens (Human) double-strand break repair via homologous recombination [GO:0000724]; endosomal transport [GO:0016197]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] GO:0000724; GO:0005634; GO:0005654; GO:0005737; GO:0005770; GO:0015031; GO:0016192; GO:0016197; GO:0016607; GO:0030119; GO:0044599 44189 XM_044307483.1 0 0 0 0 12 P06803 2.27e-58 Serine/threonine-protein kinase pim-1 (EC 2.7.11.1) Mus musculus (Mouse) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cellular detoxification [GO:1990748]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cardioblast proliferation [GO:1905062]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of transmembrane transporter activity [GO:0022898]; vitamin D receptor signaling pathway [GO:0070561] GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0005886; GO:0006468; GO:0006915; GO:0007049; GO:0022898; GO:0030145; GO:0043024; GO:0043066; GO:0043433; GO:0043539; GO:0045737; GO:0045893; GO:0046777; GO:0050821; GO:0060045; GO:0070561; GO:0071902; GO:0090336; GO:0106310; GO:1902033; GO:1905062; GO:1990748 44190 XM_044313422.1 4 0 0 2 8 NA NA NA NA NA NA 44191 XM_029342643.2 1055 187 248 2583 405 Q58A42 1.99e-73 Protein DD3-3 Dictyostelium discoideum (Social amoeba) NA GO:0016020 44192 XM_029335493.2 3444 4301 1822 3263 2819 P70011 1.58e-76 Nucleoside diphosphate kinase A2 (NDK A2) (NDP kinase A2) (EC 2.7.4.6) (NM23/nucleoside diphosphate kinase A2) Xenopus laevis (African clawed frog) CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside diphosphate phosphorylation [GO:0006165]; UTP biosynthetic process [GO:0006228] GO:0004550; GO:0005524; GO:0005737; GO:0006165; GO:0006183; GO:0006228; GO:0006241; GO:0046872 44193 XM_029335493.2 3444 4301 1822 3263 2819 P70011 8.59e-58 Nucleoside diphosphate kinase A2 (NDK A2) (NDP kinase A2) (EC 2.7.4.6) (NM23/nucleoside diphosphate kinase A2) Xenopus laevis (African clawed frog) CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside diphosphate phosphorylation [GO:0006165]; UTP biosynthetic process [GO:0006228] GO:0004550; GO:0005524; GO:0005737; GO:0006165; GO:0006183; GO:0006228; GO:0006241; GO:0046872 44194 XR_006392322.1 0 0 0 14 0 NA NA NA NA NA NA 44195 XM_044307354.1 28 2 11 11 30 NA NA NA NA NA NA 44196 XM_044308410.1 0 0 44 288 44 NA NA NA NA NA NA 44197 XM_029351579.1 1886 1736 868 1461 1091 Q9DCU6 2.77e-51 39S ribosomal protein L4, mitochondrial (L4mt) (MRP-L4) Mus musculus (Mouse) mitochondrial translation [GO:0032543] GO:0003735; GO:0005739; GO:0005743; GO:0005762; GO:0032543 44198 XM_029348434.2 567 415 197 370 453 NA NA NA NA NA NA 44199 XM_029342507.2 24 9 7 71 14 P07338 3.69e-39 Chymotrypsinogen B (EC 3.4.21.1) [Cleaved into: Chymotrypsin B chain A; Chymotrypsin B chain B; Chymotrypsin B chain C] Rattus norvegicus (Rat) digestion [GO:0007586]; positive regulation of apoptotic process [GO:0043065]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to cytokine [GO:0034097]; response to food [GO:0032094]; response to nutrient [GO:0007584]; response to peptide hormone [GO:0043434]; response to toxic substance [GO:0009636] GO:0004252; GO:0005615; GO:0005737; GO:0005764; GO:0006508; GO:0007584; GO:0007586; GO:0008233; GO:0008236; GO:0009636; GO:0030163; GO:0032094; GO:0034097; GO:0043065; GO:0043434 44200 XM_029323464.2 297 125 136 107 583 J7GQ11 1.79e-77 L-tyrosine decarboxylase (TDC) (EC 4.1.1.25) Levilactobacillus brevis (Lactobacillus brevis) carboxylic acid metabolic process [GO:0019752] GO:0004837; GO:0019752; GO:0030170; GO:0036468 44201 XM_044308765.1 3242 4227 5566 6321 5294 Q0KIA2 1.47e-54 PP2C-like domain-containing protein CG9801 Drosophila melanogaster (Fruit fly) NA NA 44202 XM_044319939.1 349 0 86 365 82 O88576 6.73e-168 Sodium-dependent neutral amino acid transporter B(0)AT3 (Sodium- and chloride-dependent transporter XTRP2) (Solute carrier family 6 member 18) (System B(0) neutral amino acid transporter AT3) Mus musculus (Mouse) amino acid transmembrane transport [GO:0003333]; neurotransmitter transport [GO:0006836]; neutral amino acid transport [GO:0015804]; renal amino acid absorption [GO:1990297]; sodium ion transmembrane transport [GO:0035725] GO:0003333; GO:0005886; GO:0006836; GO:0015175; GO:0015804; GO:0016324; GO:0031526; GO:0035725; GO:0140931; GO:1990297 44203 XR_003828478.2 82 25 23 55 66 NA NA NA NA NA NA 44204 XM_029325258.2 25 0 0 6 13 NA NA NA NA NA NA 44205 XM_044326869.1 260 740 406 888 789 NA NA NA NA NA NA 44206 XM_044323042.1 797 243 309 1075 712 Q60847 1.36e-26 Collagen alpha-1(XII) chain Mus musculus (Mouse) cell adhesion [GO:0007155]; endodermal cell differentiation [GO:0035987] GO:0005595; GO:0005615; GO:0007155; GO:0035987; GO:0062023 44207 XM_044323042.1 797 243 309 1075 712 Q60847 4.17e-21 Collagen alpha-1(XII) chain Mus musculus (Mouse) cell adhesion [GO:0007155]; endodermal cell differentiation [GO:0035987] GO:0005595; GO:0005615; GO:0007155; GO:0035987; GO:0062023 44208 XM_029345086.2 552 353 254 110 762 A2AKX3 8.41e-87 Probable helicase senataxin (EC 3.6.4.-) (Amyotrophic lateral sclerosis 4 protein homolog) (SEN1 homolog) Mus musculus (Mouse) cell differentiation [GO:0030154]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to oxidative stress [GO:0034599]; cellular response to retinoic acid [GO:0071300]; circadian rhythm [GO:0007623]; DNA recombination [GO:0006310]; DNA-templated transcription termination [GO:0006353]; double-strand break repair [GO:0006302]; fibroblast growth factor receptor signaling pathway [GO:0008543]; MAPK cascade [GO:0000165]; mRNA splice site selection [GO:0006376]; negative regulation of apoptotic process [GO:0043066]; nervous system development [GO:0007399]; positive regulation of DNA-templated transcription initiation [GO:2000144]; positive regulation of neuron projection development [GO:0010976]; positive regulation of RNA splicing [GO:0033120]; positive regulation of termination of DNA-templated transcription [GO:0060566]; positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled [GO:2000806]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein kinase B signaling [GO:0043491]; spermatogenesis [GO:0007283]; termination of RNA polymerase II transcription [GO:0006369] GO:0000165; GO:0000228; GO:0000781; GO:0001147; GO:0003723; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0006302; GO:0006310; GO:0006353; GO:0006369; GO:0006376; GO:0006974; GO:0007283; GO:0007399; GO:0007623; GO:0008543; GO:0010976; GO:0016604; GO:0016787; GO:0030154; GO:0030424; GO:0030426; GO:0033120; GO:0034599; GO:0042802; GO:0043066; GO:0043491; GO:0044344; GO:0045171; GO:0045944; GO:0060566; GO:0070301; GO:0071300; GO:2000144; GO:2000806 44209 XM_029345086.2 552 353 254 110 762 A2AKX3 1.05e-31 Probable helicase senataxin (EC 3.6.4.-) (Amyotrophic lateral sclerosis 4 protein homolog) (SEN1 homolog) Mus musculus (Mouse) cell differentiation [GO:0030154]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to oxidative stress [GO:0034599]; cellular response to retinoic acid [GO:0071300]; circadian rhythm [GO:0007623]; DNA recombination [GO:0006310]; DNA-templated transcription termination [GO:0006353]; double-strand break repair [GO:0006302]; fibroblast growth factor receptor signaling pathway [GO:0008543]; MAPK cascade [GO:0000165]; mRNA splice site selection [GO:0006376]; negative regulation of apoptotic process [GO:0043066]; nervous system development [GO:0007399]; positive regulation of DNA-templated transcription initiation [GO:2000144]; positive regulation of neuron projection development [GO:0010976]; positive regulation of RNA splicing [GO:0033120]; positive regulation of termination of DNA-templated transcription [GO:0060566]; positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled [GO:2000806]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein kinase B signaling [GO:0043491]; spermatogenesis [GO:0007283]; termination of RNA polymerase II transcription [GO:0006369] GO:0000165; GO:0000228; GO:0000781; GO:0001147; GO:0003723; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0006302; GO:0006310; GO:0006353; GO:0006369; GO:0006376; GO:0006974; GO:0007283; GO:0007399; GO:0007623; GO:0008543; GO:0010976; GO:0016604; GO:0016787; GO:0030154; GO:0030424; GO:0030426; GO:0033120; GO:0034599; GO:0042802; GO:0043066; GO:0043491; GO:0044344; GO:0045171; GO:0045944; GO:0060566; GO:0070301; GO:0071300; GO:2000144; GO:2000806 44210 XM_029338051.2 380 278 223 295 466 E1BE02 9.12e-58 Transcription factor E2F7 (E2F-7) Bos taurus (Bovine) chorionic trophoblast cell differentiation [GO:0060718]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; hepatocyte differentiation [GO:0070365]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cytokinesis [GO:0032466]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0071930]; placenta development [GO:0001890]; positive regulation of DNA endoreduplication [GO:0032877]; regulation of transcription by RNA polymerase II [GO:0006357]; sprouting angiogenesis [GO:0002040]; trophoblast giant cell differentiation [GO:0060707] GO:0000122; GO:0000978; GO:0000981; GO:0001217; GO:0001890; GO:0002040; GO:0003700; GO:0006357; GO:0008285; GO:0030330; GO:0032466; GO:0032877; GO:0060707; GO:0060718; GO:0070365; GO:0071930; GO:0090575; GO:2000134 44211 XM_029341719.2 177 190 126 172 121 NA NA NA NA NA NA 44212 XM_029343374.2 127 160 45 93 273 NA NA NA NA NA NA 44213 XM_029328695.2 694 529 180 549 340 NA NA NA NA NA NA 44214 XM_029326833.2 7158 11184 7691 10725 7673 Q5RBP4 0 EH domain-containing protein 1 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cellular response to nerve growth factor stimulus [GO:1990090]; cilium assembly [GO:0060271]; endocytic recycling [GO:0032456]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; neuron projection development [GO:0031175]; positive regulation of endocytic recycling [GO:2001137]; positive regulation of myoblast fusion [GO:1901741]; protein localization to cilium [GO:0061512] GO:0005509; GO:0005524; GO:0005525; GO:0005886; GO:0006886; GO:0006897; GO:0010008; GO:0020018; GO:0031175; GO:0031901; GO:0032456; GO:0055038; GO:0060271; GO:0061512; GO:1901741; GO:1990090; GO:2001137 44215 XM_044319262.1 31 33 10 58 54 G1T469 2.84e-32 NA NA NA NA 44216 XM_044313587.1 14 0 2 3 4 NA NA NA NA NA NA 44217 XR_003822702.2 192857 268348 147553 129894 126787 NA NA NA NA NA NA 44218 XM_029329498.2 2409 1667 711 1727 1406 NA NA NA NA NA NA 44219 XM_044320027.1 362 259 192 388 421 Q7ZVE6 0 Protein O-glucosyltransferase 2 (EC 2.4.1.-) (KDEL motif-containing protein 1) (Protein O-xylosyltransferase POGLUT2) (EC 2.4.2.-) Danio rerio (Zebrafish) (Brachydanio rerio) protein O-linked glycosylation via serine [GO:0018242] GO:0005788; GO:0012505; GO:0018242; GO:0035251; GO:0035252; GO:0046527; GO:0140561; GO:0140562 44220 XM_044311808.1 1 14 6 5 7 Q96AY4 1.28e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44221 XM_044311808.1 1 14 6 5 7 Q96AY4 2.21e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44222 XM_044311808.1 1 14 6 5 7 Q96AY4 3.67e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44223 XM_044311808.1 1 14 6 5 7 Q96AY4 1.54e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44224 XM_044311808.1 1 14 6 5 7 Q96AY4 1.22e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44225 XM_044311808.1 1 14 6 5 7 Q96AY4 4.2e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44226 XM_044311808.1 1 14 6 5 7 Q96AY4 1.34e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44227 XM_044311808.1 1 14 6 5 7 Q96AY4 7.57e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44228 XM_044311808.1 1 14 6 5 7 Q96AY4 1.09e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44229 XM_044311808.1 1 14 6 5 7 Q96AY4 1.79e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44230 XM_044311808.1 1 14 6 5 7 Q96AY4 4.72e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44231 XR_003825827.2 67 1 53 9 256 NA NA NA NA NA NA 44232 XM_044324535.1 21 4 8 3 5 NA NA NA NA NA NA 44233 XM_044324181.1 0 115 44 60 0 Q5RDC1 5.76e-31 WASH complex subunit 2 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) protein localization to endosome [GO:0036010]; retrograde transport, endosome to Golgi [GO:0042147] GO:0005769; GO:0005829; GO:0005886; GO:0031901; GO:0036010; GO:0042147; GO:0071203 44234 XM_029356389.2 1322 891 931 1427 1719 Q96T37 9.54e-70 RNA-binding protein 15 (One-twenty two protein 1) (RNA-binding motif protein 15) Homo sapiens (Human) branching involved in blood vessel morphogenesis [GO:0001569]; dosage compensation by inactivation of X chromosome [GO:0009048]; negative regulation of myeloid cell differentiation [GO:0045638]; placenta blood vessel development [GO:0060674]; positive regulation of transcription of Notch receptor target [GO:0007221]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of megakaryocyte differentiation [GO:0045652]; RNA methylation [GO:0001510]; spleen development [GO:0048536]; thrombopoietin-mediated signaling pathway [GO:0038163]; ventricular septum morphogenesis [GO:0060412] GO:0000381; GO:0001510; GO:0001569; GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0007221; GO:0009048; GO:0016607; GO:0031965; GO:0036396; GO:0038163; GO:0045638; GO:0045652; GO:0048536; GO:0060412; GO:0060674 44235 XM_029356389.2 1322 891 931 1427 1719 Q96T37 2.26e-37 RNA-binding protein 15 (One-twenty two protein 1) (RNA-binding motif protein 15) Homo sapiens (Human) branching involved in blood vessel morphogenesis [GO:0001569]; dosage compensation by inactivation of X chromosome [GO:0009048]; negative regulation of myeloid cell differentiation [GO:0045638]; placenta blood vessel development [GO:0060674]; positive regulation of transcription of Notch receptor target [GO:0007221]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of megakaryocyte differentiation [GO:0045652]; RNA methylation [GO:0001510]; spleen development [GO:0048536]; thrombopoietin-mediated signaling pathway [GO:0038163]; ventricular septum morphogenesis [GO:0060412] GO:0000381; GO:0001510; GO:0001569; GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0007221; GO:0009048; GO:0016607; GO:0031965; GO:0036396; GO:0038163; GO:0045638; GO:0045652; GO:0048536; GO:0060412; GO:0060674 44236 XR_006395668.1 122 50 221 59 509 NA NA NA NA NA NA 44237 XM_044315791.1 68 119 3 314 0 NA NA NA NA NA NA 44238 XM_044323648.1 31 1 28 8 125 Q1RLU1 5.69e-23 BRCA1-associated ATM activator 1 (BRCA1-associated protein required for ATM activation protein 1) Danio rerio (Zebrafish) (Brachydanio rerio) cell population proliferation [GO:0008283]; cellular response to DNA damage stimulus [GO:0006974]; positive regulation of protein phosphorylation [GO:0001934]; response to ionizing radiation [GO:0010212] GO:0001934; GO:0005634; GO:0005737; GO:0006974; GO:0008283; GO:0010212 44239 XM_044328190.1 0 509 0 280 135 NA NA NA NA NA NA 44240 XM_029331983.2 13169 5684 395 6297 6602 NA NA NA NA NA NA 44241 XM_029328471.2 2221 626 1518 409 397 NA NA NA NA NA NA 44242 XM_029332347.2 45 18 40 32 61 Q8BG58 1.03e-39 Transmembrane prolyl 4-hydroxylase (P4H-TM) (EC 1.14.11.29) (Hypoxia-inducible factor prolyl hydroxylase 4) (HIF-PH4) (HIF-prolyl hydroxylase 4) (HPH-4) Mus musculus (Mouse) peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; regulation of erythrocyte differentiation [GO:0045646] GO:0004656; GO:0005506; GO:0005509; GO:0005783; GO:0005789; GO:0016706; GO:0018401; GO:0031418; GO:0045646 44243 XR_006397322.1 204 93 129 53 508 NA NA NA NA NA NA 44244 XM_044317883.1 0 0 44 0 94 P54131 2.78e-67 Neuronal acetylcholine receptor subunit alpha-7 Bos taurus (Bovine) calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; cognition [GO:0050890]; ion transmembrane transport [GO:0034220]; negative regulation of tumor necrosis factor production [GO:0032720]; nervous system process [GO:0050877]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAPK cascade [GO:0043410]; regulation of membrane potential [GO:0042391]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271] GO:0001540; GO:0001666; GO:0005231; GO:0005886; GO:0005892; GO:0006816; GO:0006874; GO:0007165; GO:0007268; GO:0007271; GO:0008284; GO:0015464; GO:0015643; GO:0017081; GO:0022848; GO:0030594; GO:0032720; GO:0034220; GO:0035094; GO:0042166; GO:0042391; GO:0042803; GO:0043005; GO:0043410; GO:0045202; GO:0045211; GO:0045766; GO:0050877; GO:0050890; GO:1904315 44245 XM_029330028.2 95 85 0 75 0 O18276 4.56e-60 Gamma-aminobutyric acid receptor subunit beta (GABA(A) receptor subunit beta) Caenorhabditis elegans chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165] GO:0004890; GO:0005230; GO:0005231; GO:0005254; GO:0005886; GO:0006811; GO:0007165; GO:0007268; GO:0030594; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:1902476; GO:1902711; GO:1904315 44246 XR_006396635.1 39 18 0 11 0 NA NA NA NA NA NA 44247 XM_044308813.1 9 27 11 0 17 NA NA NA NA NA NA 44248 XM_029340295.2 14 80 36 46 60 Q4ZQC6 1.26e-38 Peptide methionine sulfoxide reductase MsrB (EC 1.8.4.12) (Peptide-methionine (R)-S-oxide reductase) Pseudomonas syringae pv. syringae (strain B728a) protein repair [GO:0030091]; response to oxidative stress [GO:0006979] GO:0006979; GO:0008270; GO:0030091; GO:0033743 44249 XM_029351943.2 275 154 79 123 130 Q9QZ41 9.92e-30 Protein DBF4 homolog A (MuDBF4) Mus musculus (Mouse) cell cycle [GO:0007049]; DNA replication [GO:0006260]; positive regulation of nuclear cell cycle DNA replication [GO:0010571]; regulation of cell cycle phase transition [GO:1901987]; traversing start control point of mitotic cell cycle [GO:0007089] GO:0003676; GO:0004674; GO:0005634; GO:0005654; GO:0006260; GO:0007049; GO:0007089; GO:0008270; GO:0010571; GO:0016604; GO:0031431; GO:0043539; GO:1901987 44250 XR_006397350.1 134 0 36 141 12 NA NA NA NA NA NA 44251 XM_044309893.1 187 271 31 150 117 NA NA NA NA NA NA 44252 XM_029335720.2 708 957 716 895 1425 NA NA NA NA NA NA 44253 XM_029324172.2 844 855 591 930 816 Q14BP6 1.24e-52 Leucine-rich repeat-containing protein 74B Mus musculus (Mouse) NA NA 44254 XR_003824890.2 604 2111 993 705 631 NA NA NA NA NA NA 44255 XR_006393103.1 48 13 77 54 329 NA NA NA NA NA NA 44256 XM_044323968.1 0 105 205 371 67 NA NA NA NA NA NA 44257 XM_029344468.2 1050 592 1008 859 773 Q9NQB0 4.07e-41 Transcription factor 7-like 2 (HMG box transcription factor 4) (T-cell-specific transcription factor 4) (T-cell factor 4) (TCF-4) (hTCF-4) Homo sapiens (Human) blood vessel development [GO:0001568]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition [GO:0044334]; fat cell differentiation [GO:0045444]; glucose homeostasis [GO:0042593]; maintenance of DNA repeat elements [GO:0043570]; myoblast fate commitment [GO:0048625]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type B pancreatic cell apoptotic process [GO:2000675]; pancreas development [GO:0031016]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of heparan sulfate proteoglycan biosynthetic process [GO:0010909]; positive regulation of insulin secretion [GO:0032024]; positive regulation of protein binding [GO:0032092]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of hormone metabolic process [GO:0032350]; regulation of smooth muscle cell proliferation [GO:0048660]; regulation of transcription by RNA polymerase II [GO:0006357]; response to glucose [GO:0009749] GO:0000122; GO:0000785; GO:0000976; GO:0000978; GO:0000981; GO:0001568; GO:0003676; GO:0003700; GO:0005634; GO:0005654; GO:0006357; GO:0008013; GO:0009749; GO:0010909; GO:0016605; GO:0016922; GO:0019901; GO:0031016; GO:0032024; GO:0032092; GO:0032350; GO:0032993; GO:0042593; GO:0043433; GO:0043565; GO:0043570; GO:0044334; GO:0045295; GO:0045444; GO:0045892; GO:0045944; GO:0048625; GO:0048660; GO:0050679; GO:0051897; GO:0060070; GO:0060090; GO:0061629; GO:0070016; GO:0070369; GO:0071664; GO:0090090; GO:1900182; GO:1990907; GO:2000675; GO:2001237 44258 XM_044321925.1 0 0 92 0 0 NA NA NA NA NA NA 44259 XM_029335827.2 1939 4141 76 1882 1997 NA NA NA NA NA NA 44260 XR_006395855.1 60 79 25 38 72 Q9Y239 2.48e-24 Nucleotide-binding oligomerization domain-containing protein 1 (Caspase recruitment domain-containing protein 4) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cellular response to muramyl dipeptide [GO:0071225]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; ERK1 and ERK2 cascade [GO:0070371]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of cell death [GO:0010942]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of xenophagy [GO:1904417]; regulation of apoptotic process [GO:0042981]; signal transduction [GO:0007165]; xenophagy [GO:0098792] GO:0002221; GO:0002606; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006915; GO:0006919; GO:0006952; GO:0006954; GO:0007165; GO:0007249; GO:0007254; GO:0008656; GO:0009595; GO:0010942; GO:0016045; GO:0016323; GO:0016324; GO:0032731; GO:0032755; GO:0032757; GO:0032760; GO:0035556; GO:0038187; GO:0042742; GO:0042802; GO:0042803; GO:0042834; GO:0042981; GO:0043123; GO:0043280; GO:0044877; GO:0045087; GO:0045335; GO:0046330; GO:0050700; GO:0050830; GO:0051000; GO:0051092; GO:0060907; GO:0070371; GO:0070374; GO:0071225; GO:0098792; GO:1901224; GO:1904417 44261 XM_044325569.1 193 0 116 26 6 O54748 0 Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) (MST-2) (STE20-like kinase MST2) [Cleaved into: Serine/threonine-protein kinase 3 36kDa subunit (MST2/N); Serine/threonine-protein kinase 3 20kDa subunit (MST2/C)] Rattus norvegicus (Rat) apoptotic process [GO:0006915]; canonical Wnt signaling pathway [GO:0060070]; cell differentiation involved in embryonic placenta development [GO:0060706]; cell population proliferation [GO:0008283]; central nervous system development [GO:0007417]; endocardium development [GO:0003157]; epithelial cell proliferation [GO:0050673]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; hepatocyte apoptotic process [GO:0097284]; hippo signaling [GO:0035329]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of organ growth [GO:0046621]; neural tube formation [GO:0001841]; organ growth [GO:0035265]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein binding [GO:0032092]; positive regulation of protein kinase B signaling [GO:0051897]; primitive hemopoiesis [GO:0060215]; protein import into nucleus [GO:0006606]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; regulation of cell differentiation involved in embryonic placenta development [GO:0060800]; regulation of MAPK cascade [GO:0043408]; selective autophagy [GO:0061912] GO:0000287; GO:0001841; GO:0003157; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0006468; GO:0006606; GO:0006915; GO:0007254; GO:0007417; GO:0008283; GO:0008285; GO:0008625; GO:0032092; GO:0032991; GO:0035265; GO:0035329; GO:0035556; GO:0042802; GO:0043065; GO:0043408; GO:0043491; GO:0045600; GO:0046330; GO:0046621; GO:0050673; GO:0050680; GO:0050821; GO:0051091; GO:0051262; GO:0051897; GO:0060070; GO:0060215; GO:0060706; GO:0060800; GO:0061912; GO:0090090; GO:0097284; GO:0106310; GO:1902043 44262 XM_044322781.1 0 0 7 57 28 Q94887 1.3e-29 Neurexin-4 (Neurexin IV) Drosophila melanogaster (Fruit fly) axon ensheathment [GO:0008366]; cell adhesion involved in heart morphogenesis [GO:0061343]; cell-cell junction organization [GO:0045216]; dorsal closure [GO:0007391]; establishment of glial blood-brain barrier [GO:0060857]; heart process [GO:0003015]; nerve maturation [GO:0021682]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]; synaptic target recognition [GO:0008039]; terminal button organization [GO:0072553] GO:0003015; GO:0005886; GO:0005919; GO:0007391; GO:0008039; GO:0008104; GO:0008366; GO:0019991; GO:0021682; GO:0035151; GO:0045202; GO:0045216; GO:0048786; GO:0060857; GO:0061343; GO:0072553; GO:0097105 44263 XM_044317472.1 0 0 0 0 8 NA NA NA NA NA NA 44264 XM_029352127.2 588 393 246 613 739 A7S6A5 0 Protein SDA1 homolog (SDA1 domain-containing protein 1 homolog) Nematostella vectensis (Starlet sea anemone) protein transport [GO:0015031]; ribosomal large subunit biogenesis [GO:0042273]; ribosomal large subunit export from nucleus [GO:0000055] GO:0000055; GO:0005730; GO:0015031; GO:0042273 44265 XM_044319730.1 1656 2270 1658 2182 1343 NA NA NA NA NA NA 44266 XM_044323074.1 12 9 8 0 17 NA NA NA NA NA NA 44267 XR_006397259.1 42 0 0 0 0 NA NA NA NA NA NA 44268 XM_029351073.2 0 14 0 31 515 NA NA NA NA NA NA 44269 XM_044326121.1 0 0 0 1 8 NA NA NA NA NA NA 44270 XM_044325847.1 5591 2444 169 60 1627 NA NA NA NA NA NA 44271 XM_044306936.1 3092 2241 2122 2950 3660 A0A1D5P556 2.87e-157 Disheveled-associated activator of morphogenesis 2 Gallus gallus (Chicken) actin cytoskeleton organization [GO:0030036]; dorsal spinal cord development [GO:0021516]; negative regulation of oligodendrocyte differentiation [GO:0048715]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of non-canonical Wnt signaling pathway [GO:2000050]; Wnt signaling pathway [GO:0016055] GO:0003779; GO:0016055; GO:0021516; GO:0030036; GO:0031267; GO:0048715; GO:0060828; GO:0090263; GO:2000050 44272 XM_044306936.1 3092 2241 2122 2950 3660 A0A1D5P556 1.85e-130 Disheveled-associated activator of morphogenesis 2 Gallus gallus (Chicken) actin cytoskeleton organization [GO:0030036]; dorsal spinal cord development [GO:0021516]; negative regulation of oligodendrocyte differentiation [GO:0048715]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of non-canonical Wnt signaling pathway [GO:2000050]; Wnt signaling pathway [GO:0016055] GO:0003779; GO:0016055; GO:0021516; GO:0030036; GO:0031267; GO:0048715; GO:0060828; GO:0090263; GO:2000050 44273 XM_044307341.1 7 30 0 76 77 P79385 8.72e-23 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (SED1) (Sperm surface protein SP47) (PP47) Sus scrofa (Pig) angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; single fertilization [GO:0007338] GO:0001525; GO:0002080; GO:0005576; GO:0007155; GO:0007338 44274 XM_044308046.1 359 179 105 255 336 Q8C1A5 0 Thimet oligopeptidase (EC 3.4.24.15) Mus musculus (Mouse) intracellular signal transduction [GO:0035556]; peptide catabolic process [GO:0043171]; peptide metabolic process [GO:0006518]; proteolysis [GO:0006508] GO:0004222; GO:0005758; GO:0006508; GO:0006518; GO:0008233; GO:0035556; GO:0042277; GO:0043171; GO:0046872 44275 XM_029349361.2 610 179 270 341 569 B1AUE5 2.04e-73 Peroxisome biogenesis factor 10 (EC 2.3.2.27) (Peroxin-10) (Peroxisomal biogenesis factor 10) (Peroxisome assembly protein 10) Mus musculus (Mouse) peroxisome organization [GO:0007031]; protein import into peroxisome matrix [GO:0016558]; protein import into peroxisome matrix, receptor recycling [GO:0016562] GO:0005777; GO:0005778; GO:0007031; GO:0008022; GO:0016558; GO:0016562; GO:0046872; GO:0061630 44276 XM_029323973.2 244 353 270 170 343 Q6P5E8 0 Diacylglycerol kinase theta (DAG kinase theta) (EC 2.7.1.107) (Diglyceride kinase theta) (DGK-theta) Mus musculus (Mouse) cAMP-mediated signaling [GO:0019933]; diacylglycerol metabolic process [GO:0046339]; G protein-coupled receptor signaling pathway [GO:0007186]; glycerolipid metabolic process [GO:0046486]; intracellular signal transduction [GO:0035556]; lipid phosphorylation [GO:0046834]; negative regulation of gene expression [GO:0010629]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; peptidyl-serine phosphorylation [GO:0018105]; phosphatidic acid biosynthetic process [GO:0006654]; positive regulation of gene expression [GO:0010628]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; protein kinase C signaling [GO:0070528]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; regulation of cholesterol metabolic process [GO:0090181]; regulation of cortisol biosynthetic process [GO:2000064]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; regulation of gluconeogenesis [GO:0006111]; regulation of progesterone biosynthetic process [GO:2000182]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of TORC1 signaling [GO:1903432]; regulation of transcription by RNA polymerase II [GO:0006357]; response to ATP [GO:0033198]; response to cAMP [GO:0051591]; thrombin-activated receptor signaling pathway [GO:0070493] GO:0004143; GO:0005524; GO:0005634; GO:0005737; GO:0005768; GO:0005829; GO:0005856; GO:0005886; GO:0006111; GO:0006357; GO:0006654; GO:0007186; GO:0007205; GO:0008277; GO:0010628; GO:0010629; GO:0010801; GO:0012506; GO:0016363; GO:0016607; GO:0018105; GO:0019900; GO:0019933; GO:0030297; GO:0033198; GO:0035556; GO:0043274; GO:0046339; GO:0046486; GO:0046834; GO:0046872; GO:0050731; GO:0051591; GO:0070493; GO:0070528; GO:0090181; GO:0098793; GO:0098794; GO:0098978; GO:0140297; GO:1900242; GO:1903432; GO:2000064; GO:2000182 44277 XR_006393544.1 171 371 70 92 77 Q9BWT3 0 Poly(A) polymerase gamma (PAP-gamma) (EC 2.7.7.19) (Neo-poly(A) polymerase) (Neo-PAP) (Polynucleotide adenylyltransferase gamma) (SRP RNA 3'-adenylating enzyme) (Signal recognition particle RNA-adenylating enzyme) (SRP RNA-adenylating enzyme) Homo sapiens (Human) mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631] GO:0003723; GO:0004652; GO:0005524; GO:0005634; GO:0005654; GO:0005829; GO:0006378; GO:0016020; GO:0016604; GO:0043631; GO:0046872 44278 XR_006392291.1 63 67 142 18 29 NA NA NA NA NA NA 44279 XM_029349921.2 933 558 566 909 643 P54289 2.89e-128 Voltage-dependent calcium channel subunit alpha-2/delta-1 (Voltage-gated calcium channel subunit alpha-2/delta-1) [Cleaved into: Voltage-dependent calcium channel subunit alpha-2-1; Voltage-dependent calcium channel subunit delta-1] Homo sapiens (Human) calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; calcium ion transmembrane transport via high voltage-gated calcium channel [GO:0061577]; calcium ion transport [GO:0006816]; calcium ion transport into cytosol [GO:0060402]; cardiac muscle cell action potential involved in contraction [GO:0086002]; cellular response to amyloid-beta [GO:1904646]; membrane depolarization during bundle of His cell action potential [GO:0086048]; positive regulation of high voltage-gated calcium channel activity [GO:1901843]; positive regulation of muscle contraction [GO:0045933]; regulation of calcium ion transmembrane transport via high voltage-gated calcium channel [GO:1902514]; regulation of calcium ion transport [GO:0051924]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of membrane repolarization during action potential [GO:0098903]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307] GO:0005245; GO:0005891; GO:0006816; GO:0016529; GO:0045933; GO:0046872; GO:0051924; GO:0060307; GO:0060402; GO:0061577; GO:0070062; GO:0070588; GO:0086002; GO:0086048; GO:0086091; GO:0098703; GO:0098903; GO:0098992; GO:1901843; GO:1902514; GO:1904646; GO:1990454 44280 XM_029340887.2 112 123 97 170 133 P29146 0 PC3-like endoprotease variant A (EC 3.4.21.-) (SPC3) Hydra vulgaris (Hydra) (Hydra attenuata) proteolysis [GO:0006508] GO:0004252; GO:0006508 44281 XM_029340651.2 347 379 137 366 346 NA NA NA NA NA NA 44282 XM_044315595.1 3 0 3 8 44 NA NA NA NA NA NA 44283 XM_044313855.1 14 6 11 7 33 NA NA NA NA NA NA 44284 XM_044311266.1 59 135 18 34 165 NA NA NA NA NA NA 44285 XM_029335563.2 71 0 0 55 0 NA NA NA NA NA NA 44286 XM_044309024.1 258 226 50 81 188 P20664 2.85e-160 DNA primase small subunit (EC 2.7.7.102) (DNA primase 49 kDa subunit) (p49) Mus musculus (Mouse) DNA replication initiation [GO:0006270]; DNA replication, synthesis of RNA primer [GO:0006269] GO:0000287; GO:0003896; GO:0005658; GO:0006269; GO:0006270; GO:0008270; GO:0032553 44287 XM_029357222.2 64 0 25 0 150 P49288 5.94e-24 Melatonin receptor type 1C (Mel-1C-R) (Mel1c receptor) (CKB) Gallus gallus (Chicken) G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of glucose import [GO:0046325]; negative regulation of glycolytic process [GO:0045820] GO:0004930; GO:0005654; GO:0005886; GO:0007186; GO:0008502; GO:0045820; GO:0046325; GO:1904408 44288 XM_044316278.1 393 170 153 187 435 Q9Y6A2 3.6e-66 Cholesterol 24-hydroxylase (CH24H) (EC 1.14.14.25) (Cholesterol 24-monooxygenase) (Cholesterol 24S-hydroxylase) (Cytochrome P450 46A1) Homo sapiens (Human) bile acid biosynthetic process [GO:0006699]; cholesterol catabolic process [GO:0006707]; nervous system development [GO:0007399]; progesterone metabolic process [GO:0042448]; protein localization to membrane raft [GO:1903044]; regulation of long-term synaptic potentiation [GO:1900271]; sterol metabolic process [GO:0016125]; xenobiotic metabolic process [GO:0006805] GO:0005506; GO:0005783; GO:0005789; GO:0006699; GO:0006707; GO:0006805; GO:0007399; GO:0008395; GO:0016125; GO:0020037; GO:0030425; GO:0033781; GO:0042448; GO:0062184; GO:0098793; GO:0098794; GO:1900271; GO:1903044 44289 XM_029329537.2 165 87 86 194 152 P30974 2.21e-29 Tachykinin-like peptides receptor 86C (NKD) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; inter-male aggressive behavior [GO:0002121]; neuropeptide signaling pathway [GO:0007218]; tachykinin receptor signaling pathway [GO:0007217] GO:0002121; GO:0004995; GO:0005886; GO:0007186; GO:0007217; GO:0007218; GO:0008188; GO:0016020 44290 XM_044310832.1 153 146 99 88 133 NA NA NA NA NA NA 44291 XM_029348551.2 528 670 200 598 420 B1H283 4.32e-66 Lymphocyte expansion molecule Rattus norvegicus (Rat) positive regulation of cell population proliferation [GO:0008284]; positive regulation of oxidative phosphorylation [GO:1903862] GO:0005739; GO:0008284; GO:0097177; GO:1903862 44292 XM_029346946.2 15 246 135 374 96 Q0V8S0 2.23e-130 Hepatocyte growth factor-regulated tyrosine kinase substrate Bos taurus (Bovine) endocytic recycling [GO:0032456]; membrane invagination [GO:0010324]; negative regulation of angiogenesis [GO:0016525]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of gene expression [GO:0010628]; protein localization to membrane [GO:0072657]; protein targeting to lysosome [GO:0006622]; receptor internalization [GO:0031623]; regulation of MAP kinase activity [GO:0043405] GO:0005764; GO:0005769; GO:0005829; GO:0006622; GO:0010324; GO:0010628; GO:0010642; GO:0016525; GO:0019904; GO:0030948; GO:0031623; GO:0031901; GO:0032456; GO:0032585; GO:0033565; GO:0035091; GO:0043130; GO:0043405; GO:0044389; GO:0046426; GO:0046872; GO:0072657; GO:1903543 44293 XM_044315902.1 0 0 32 0 4 NA NA NA NA NA NA 44294 XM_029338490.2 1024 861 547 686 521 Q5RAR0 1.21e-124 Translation initiation factor eIF-2B subunit alpha (eIF-2B GDP-GTP exchange factor subunit alpha) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003743 44295 XM_044316073.1 73 164 53 88 74 NA NA NA NA NA NA 44296 XM_029350459.2 25 3 25 16 105 P25291 1.06e-25 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 44297 XM_029340588.2 2044 2451 1626 1731 2177 Q5R6Z8 8.23e-45 Calcyclin-binding protein (CacyBP) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0005634; GO:0005737; GO:0015631; GO:0031625; GO:0044548 44298 XM_044323220.1 43 56 79 104 367 NA NA NA NA NA NA 44299 XM_044317813.1 1038 1198 787 1238 1472 Q8K3J1 6.35e-101 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (EC 7.1.1.2) (Complex I-23kD) (CI-23kD) (NADH-ubiquinone oxidoreductase 23 kDa subunit) Mus musculus (Mouse) aerobic respiration [GO:0009060]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrial respiratory chain complex I assembly [GO:0032981]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776]; response to oxidative stress [GO:0006979] GO:0003954; GO:0005739; GO:0005747; GO:0006120; GO:0006979; GO:0008137; GO:0009060; GO:0032981; GO:0042776; GO:0046872; GO:0051539 44300 XR_006395146.1 124 119 77 133 49 NA NA NA NA NA NA 44301 XM_044321176.1 5 6 10 43 105 NA NA NA NA NA NA 44302 XM_044325789.1 1 0 0 8 0 NA NA NA NA NA NA 44303 XM_029349581.2 2205 2041 965 1720 1565 P58389 9.65e-139 Serine/threonine-protein phosphatase 2A activator (EC 5.2.1.8) (PP2A, subunit B', PR53 isoform) (Phosphotyrosyl phosphatase activator) (PTPA) (Serine/threonine-protein phosphatase 2A regulatory subunit 4) (Serine/threonine-protein phosphatase 2A regulatory subunit B') Mus musculus (Mouse) mitotic spindle organization [GO:0007052]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; negative regulation of protein dephosphorylation [GO:0035308]; positive regulation of apoptotic process [GO:0043065]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of phosphoprotein phosphatase activity [GO:0043666] GO:0000159; GO:0003755; GO:0004721; GO:0005102; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0007052; GO:0008160; GO:0019888; GO:0032515; GO:0032516; GO:0034704; GO:0035307; GO:0035308; GO:0042803; GO:0043065; GO:0043666; GO:0051721; GO:1904949 44304 XM_029356633.2 2397 2969 2194 2999 2072 Q920Q8 4.77e-111 Influenza virus NS1A-binding protein homolog (NS1-BP) (NS1-binding protein homolog) (Kelch family protein Nd1-L) (ND1-L2) (Nd1-S) Mus musculus (Mouse) intrinsic apoptotic signaling pathway [GO:0097193]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of protein ubiquitination [GO:0031397]; response to virus [GO:0009615]; RNA splicing [GO:0008380] GO:0005634; GO:0005829; GO:0005856; GO:0008380; GO:0009615; GO:0031397; GO:0097193; GO:2001243 44305 XM_029341023.2 888 833 559 983 1106 O88665 2.11e-97 Bromodomain-containing protein 7 (75 kDa bromodomain protein) Mus musculus (Mouse) cell cycle [GO:0007049]; chromatin remodeling [GO:0006338]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; positive regulation of cell differentiation [GO:0045597]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of histone acetylation [GO:0035066]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of T cell differentiation [GO:0045582]; regulation of G0 to G1 transition [GO:0070316]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of nucleotide-excision repair [GO:2000819]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription initiation-coupled chromatin remodeling [GO:0045815]; Wnt signaling pathway [GO:0016055] GO:0000776; GO:0000785; GO:0000976; GO:0002039; GO:0003713; GO:0003714; GO:0005634; GO:0005654; GO:0005829; GO:0006338; GO:0006357; GO:0007049; GO:0008285; GO:0016055; GO:0016363; GO:0016586; GO:0030071; GO:0035066; GO:0042393; GO:0045582; GO:0045597; GO:0045663; GO:0045815; GO:0045892; GO:0045893; GO:0070316; GO:0070577; GO:2000045; GO:2000134; GO:2000781; GO:2000819 44306 XM_044324048.1 1206 1240 626 2320 831 D3ZZL9 9.42e-90 GRIP and coiled-coil domain-containing protein 2 (185 kDa Golgi coiled-coil protein) Rattus norvegicus (Rat) Golgi ribbon formation [GO:0090161]; late endosome to Golgi transport [GO:0034499]; microtubule anchoring [GO:0034453]; microtubule organizing center organization [GO:0031023]; protein localization to Golgi apparatus [GO:0034067]; protein targeting to lysosome [GO:0006622]; recycling endosome to Golgi transport [GO:0071955]; regulation of protein exit from endoplasmic reticulum [GO:0070861]; retrograde transport, endosome to Golgi [GO:0042147] GO:0005794; GO:0005802; GO:0005829; GO:0006622; GO:0016020; GO:0031023; GO:0034067; GO:0034453; GO:0034499; GO:0042147; GO:0042802; GO:0070861; GO:0071955; GO:0090161 44307 XR_006393853.1 0 0 0 4 10 NA NA NA NA NA NA 44308 XM_044326400.1 115 47 16 9 5 Q5R5D0 1.39e-28 Cyclin-G1 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cell cycle [GO:0007049]; cell division [GO:0051301] GO:0005634; GO:0007049; GO:0051301 44309 XM_029324159.2 1405 1179 726 1081 1119 A7RP64 4.39e-108 RNA-binding protein pno1 Nematostella vectensis (Starlet sea anemone) NA GO:0003723; GO:0005730 44310 XM_029345415.2 0 5 1 13 0 NA NA NA NA NA NA 44311 XM_029334793.2 5 1 1 0 7 NA NA NA NA NA NA 44312 XM_044310519.1 42 0 11 25 0 NA NA NA NA NA NA 44313 XM_029349600.2 0 0 1 27 34 NA NA NA NA NA NA 44314 XR_006394139.1 41 2 25 5 151 NA NA NA NA NA NA 44315 XM_044309502.1 0 0 5 0 31 NA NA NA NA NA NA 44316 XM_029330685.2 756 1090 519 1913 1384 Q9Y6F7 8.34e-38 Testis-specific chromodomain protein Y 2 (EC 2.3.1.48) Homo sapiens (Human) spermatogenesis [GO:0007283] GO:0003714; GO:0004402; GO:0005634; GO:0007283 44317 XM_044325798.1 69 0 271 34 0 Q8IZV5 1.05e-71 Retinol dehydrogenase 10 (EC 1.1.1.300) (Short chain dehydrogenase/reductase family 16C member 4) Homo sapiens (Human) bud elongation involved in lung branching [GO:0060449]; ear development [GO:0043583]; embryonic camera-type eye development [GO:0031076]; embryonic forelimb morphogenesis [GO:0035115]; embryonic viscerocranium morphogenesis [GO:0048703]; gonad development [GO:0008406]; in utero embryonic development [GO:0001701]; metanephros development [GO:0001656]; neural crest cell development [GO:0014032]; nose development [GO:0043584]; positive regulation of retinoic acid biosynthetic process [GO:1900054]; primary lung bud formation [GO:0060431]; retinal metabolic process [GO:0042574]; retinoic acid biosynthetic process [GO:0002138]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; visual perception [GO:0007601] GO:0001523; GO:0001656; GO:0001701; GO:0002138; GO:0004745; GO:0005737; GO:0005789; GO:0005811; GO:0007601; GO:0008406; GO:0014032; GO:0016020; GO:0016616; GO:0031076; GO:0035115; GO:0042572; GO:0042574; GO:0043583; GO:0043584; GO:0048703; GO:0052650; GO:0060431; GO:0060449; GO:1900054 44318 XM_044308082.1 208 0 0 88 73 Q92113 8.88e-135 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Squalus acanthias (Spiny dogfish) steroid biosynthetic process [GO:0006694] GO:0004508; GO:0005506; GO:0006694; GO:0016020; GO:0020037; GO:0047442 44319 XM_029334528.2 520 366 383 680 738 Q9NES8 0 Serine/threonine-protein phosphatase 5 (EC 3.1.3.16) Caenorhabditis elegans negative regulation of exocytosis [GO:0045920]; protein localization to organelle [GO:0033365]; regulation of protein kinase activity [GO:0045859] GO:0004721; GO:0004722; GO:0005634; GO:0005737; GO:0005829; GO:0008287; GO:0017018; GO:0032991; GO:0033365; GO:0045859; GO:0045920; GO:0046872; GO:0051879; GO:0072686; GO:0101031 44320 XM_044311950.1 0 0 0 0 25 NA NA NA NA NA NA 44321 XM_044323180.1 38 7 9 20 16 Q13591 1.46e-44 Semaphorin-5A (Semaphorin-F) (Sema F) Homo sapiens (Human) axon extension [GO:0048675]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell-cell signaling [GO:0007267]; diencephalon development [GO:0021536]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of cell adhesion [GO:0007162]; negative regulation of endothelial cell apoptotic process [GO:2000352]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; positive chemotaxis [GO:0050918]; positive regulation of actin filament depolymerization [GO:0030836]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein kinase B signaling [GO:0051897]; semaphorin-plexin signaling pathway [GO:0071526]; signal clustering [GO:1990256] GO:0001755; GO:0001938; GO:0002043; GO:0005886; GO:0007155; GO:0007162; GO:0007267; GO:0007399; GO:0007411; GO:0007413; GO:0016020; GO:0021536; GO:0030215; GO:0030335; GO:0030836; GO:0035373; GO:0043395; GO:0045499; GO:0045545; GO:0045766; GO:0048675; GO:0048842; GO:0048843; GO:0050918; GO:0051897; GO:0060326; GO:0070062; GO:0071526; GO:0090263; GO:1990256; GO:2000352; GO:2001028 44322 XM_044328562.1 127 0 0 22 0 P41413 1.18e-97 Proprotein convertase subtilisin/kexin type 5 (EC 3.4.21.-) (Proprotein convertase 5) (PC5) (Proprotein convertase 6) (PC6) (Subtilisin/kexin-like protease PC5) (rPC5) Rattus norvegicus (Rat) anterior/posterior pattern specification [GO:0009952]; cardiac septum development [GO:0003279]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; coronary vasculature development [GO:0060976]; cytokine precursor processing [GO:0140447]; determination of left/right symmetry [GO:0007368]; embryo implantation [GO:0007566]; embryonic digestive tract development [GO:0048566]; embryonic skeletal system development [GO:0048706]; heart development [GO:0007507]; kidney development [GO:0001822]; limb morphogenesis [GO:0035108]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of integrin activation [GO:0033625]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of smooth muscle cell-matrix adhesion [GO:1905609]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; protein processing [GO:0016485]; renin secretion into blood stream [GO:0002001]; respiratory tube development [GO:0030323]; response to gonadotropin [GO:0034698]; response to luteinizing hormone [GO:0034699]; signal peptide processing [GO:0006465]; vascular associated smooth muscle cell proliferation [GO:1990874]; viral life cycle [GO:0019058] GO:0000139; GO:0001822; GO:0002001; GO:0003279; GO:0004175; GO:0004252; GO:0005615; GO:0005794; GO:0005797; GO:0005802; GO:0005886; GO:0006465; GO:0007368; GO:0007507; GO:0007566; GO:0008233; GO:0009952; GO:0016020; GO:0016485; GO:0016486; GO:0019058; GO:0030323; GO:0033625; GO:0034698; GO:0034699; GO:0035108; GO:0036120; GO:0042277; GO:0043043; GO:0043204; GO:0048566; GO:0048706; GO:0060976; GO:0140447; GO:1904754; GO:1905609; GO:1990635; GO:1990874; GO:2001046 44323 XM_029327590.2 1781 1797 1343 1814 2160 C0HAC0 1.15e-73 F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5) Salmo salar (Atlantic salmon) iron ion homeostasis [GO:0055072]; protein ubiquitination [GO:0016567]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0005506; GO:0016567; GO:0019005; GO:0031146; GO:0048471; GO:0055072 44324 XM_029327590.2 1781 1797 1343 1814 2160 C0HAC0 1.03e-31 F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5) Salmo salar (Atlantic salmon) iron ion homeostasis [GO:0055072]; protein ubiquitination [GO:0016567]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0005506; GO:0016567; GO:0019005; GO:0031146; GO:0048471; GO:0055072 44325 XM_044325276.1 77 35 84 5 27 NA NA NA NA NA NA 44326 XR_003827762.2 71 5 15 2 126 NA NA NA NA NA NA 44327 XR_006392805.1 0 17 0 0 0 NA NA NA NA NA NA 44328 XR_006393951.1 261 148 52 873 182 NA NA NA NA NA NA 44329 XM_029357043.2 10 2 0 0 0 NA NA NA NA NA NA 44330 XM_044313912.1 521 251 245 98 640 NA NA NA NA NA NA 44331 XM_029348933.2 0 56 37 20 69 P50571 1.81e-77 Gamma-aminobutyric acid receptor subunit beta-1 (GABA(A) receptor subunit beta-1) Mus musculus (Mouse) cellular response to histamine [GO:0071420]; central nervous system neuron development [GO:0021954]; chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid signaling pathway [GO:0007214]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; nervous system process [GO:0050877]; ovulation cycle [GO:0042698]; regulation of membrane potential [GO:0042391]; response to progesterone [GO:0032570]; response to toxic substance [GO:0009636]; signal transduction [GO:0007165] GO:0004890; GO:0005231; GO:0005253; GO:0005634; GO:0005635; GO:0005737; GO:0005886; GO:0006811; GO:0007165; GO:0007214; GO:0007268; GO:0009636; GO:0015276; GO:0016020; GO:0021954; GO:0022851; GO:0030425; GO:0030594; GO:0032570; GO:0034220; GO:0034707; GO:0042391; GO:0042698; GO:0043005; GO:0043235; GO:0045202; GO:0048787; GO:0050811; GO:0050877; GO:0071420; GO:0098685; GO:0098982; GO:0099507; GO:0099634; GO:0150047; GO:1902476; GO:1902711; GO:1904315 44332 XM_029339303.2 6 0 2 0 2 NA NA NA NA NA NA 44333 XM_029351013.2 17 22 0 0 0 Q5R9E1 3.93e-120 Hydroxymethylglutaryl-CoA lyase, mitochondrial (HL) (HMG-CoA lyase) (EC 4.1.3.4) (3-hydroxy-3-methylglutarate-CoA lyase) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) ketone body biosynthetic process [GO:0046951] GO:0004419; GO:0005759; GO:0005777; GO:0046872; GO:0046951 44334 XM_044324078.1 26 81 31 236 66 NA NA NA NA NA NA 44335 XM_044316825.1 63 53 22 14 96 Q3T1L0 4.9e-175 Aldehyde dehydrogenase family 16 member A1 Rattus norvegicus (Rat) NA GO:0016620 44336 XM_029357789.2 45 3 0 16 10 Q9W6G7 8.71e-30 DNA polymerase subunit gamma-2, mitochondrial (Mitochondrial DNA polymerase accessory subunit) (MtPolB) (PolG-beta) Xenopus laevis (African clawed frog) mitochondrial DNA replication [GO:0006264] GO:0003677; GO:0005759; GO:0005760; GO:0006264 44337 XM_029357789.2 45 3 0 16 10 Q9W6G7 8.71e-30 DNA polymerase subunit gamma-2, mitochondrial (Mitochondrial DNA polymerase accessory subunit) (MtPolB) (PolG-beta) Xenopus laevis (African clawed frog) mitochondrial DNA replication [GO:0006264] GO:0003677; GO:0005759; GO:0005760; GO:0006264 44338 XM_044321160.1 21 48 54 15 66 Q9TXJ8 5.42e-44 Putative ATP-dependent DNA helicase Q1 (EC 3.6.4.12) Caenorhabditis elegans DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724] GO:0000724; GO:0003676; GO:0005524; GO:0005634; GO:0005694; GO:0005737; GO:0006268; GO:0006281; GO:0006310; GO:0009378; GO:0016887; GO:0032508; GO:0043138 44339 XM_029358388.2 0 6 45 23 0 Q9U3S9 1.56e-40 Zinc metalloproteinase nas-6 (EC 3.4.24.-) (Nematode astacin 6) Caenorhabditis elegans pharyngeal pumping [GO:0043050]; pharynx development [GO:0060465]; proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0006508; GO:0008270; GO:0043050; GO:0060465 44340 XM_044322953.1 274 211 220 245 127 Q99LX5 4.74e-33 Multiple myeloma tumor-associated protein 2 homolog Mus musculus (Mouse) NA NA 44341 XM_029332074.2 32 28 43 19 92 F6RIX4 0 DNA helicase MCM9 (EC 3.6.4.12) (Minichromosome maintenance 9) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cellular response to DNA damage stimulus [GO:0006974]; DNA duplex unwinding [GO:0032508]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724] GO:0000724; GO:0003677; GO:0004386; GO:0005524; GO:0005634; GO:0006260; GO:0006974; GO:0016887; GO:0032508; GO:0097362 44342 XM_029332248.2 64 175 80 44 105 Q805E5 1.15e-78 Carbohydrate sulfotransferase 14 (EC 2.8.2.-) (Dermatan 4-sulfotransferase 1) (D4ST-1) (zD4ST-1) Danio rerio (Zebrafish) (Brachydanio rerio) carbohydrate biosynthetic process [GO:0016051]; dermatan sulfate proteoglycan metabolic process [GO:0050655] GO:0000139; GO:0001537; GO:0008146; GO:0016051; GO:0050655 44343 XM_044310730.1 0 249 0 0 0 NA NA NA NA NA NA 44344 XM_029351140.2 16 23 9 46 64 P22770 1.34e-76 Neuronal acetylcholine receptor subunit alpha-7 Gallus gallus (Chicken) calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; cognition [GO:0050890]; membrane depolarization [GO:0051899]; negative regulation of tumor necrosis factor production [GO:0032720]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAPK cascade [GO:0043410]; regulation of nitric oxide metabolic process [GO:0080164]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; signal transduction [GO:0007165] GO:0001540; GO:0001666; GO:0005737; GO:0005886; GO:0005892; GO:0006816; GO:0006874; GO:0007165; GO:0008284; GO:0015464; GO:0015643; GO:0017081; GO:0022848; GO:0030424; GO:0030425; GO:0032720; GO:0035094; GO:0042166; GO:0042803; GO:0043204; GO:0043410; GO:0045211; GO:0045766; GO:0050890; GO:0051899; GO:0080164 44345 XM_044324308.1 443 284 212 317 312 Q92542 1.53e-130 Nicastrin Homo sapiens (Human) adult behavior [GO:0030534]; amyloid precursor protein biosynthetic process [GO:0042983]; amyloid precursor protein catabolic process [GO:0042987]; amyloid precursor protein metabolic process [GO:0042982]; amyloid-beta formation [GO:0034205]; cellular response to calcium ion [GO:0071277]; central nervous system myelination [GO:0022010]; cerebellum development [GO:0021549]; dopamine receptor signaling pathway [GO:0007212]; epithelial cell proliferation [GO:0050673]; glutamate receptor signaling pathway [GO:0007215]; learning or memory [GO:0007611]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; myeloid cell homeostasis [GO:0002262]; neuron apoptotic process [GO:0051402]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; positive regulation of amyloid precursor protein biosynthetic process [GO:0042986]; positive regulation of catalytic activity [GO:0043085]; positive regulation of endopeptidase activity [GO:0010950]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of long-term synaptic potentiation [GO:1900271]; short-term synaptic potentiation [GO:1990926]; T cell proliferation [GO:0042098] GO:0002262; GO:0005739; GO:0005765; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005925; GO:0006508; GO:0006509; GO:0007212; GO:0007215; GO:0007219; GO:0007220; GO:0007611; GO:0008021; GO:0010008; GO:0010950; GO:0016020; GO:0016485; GO:0021549; GO:0022010; GO:0030534; GO:0030674; GO:0031293; GO:0034205; GO:0035577; GO:0042098; GO:0042383; GO:0042470; GO:0042500; GO:0042734; GO:0042982; GO:0042983; GO:0042986; GO:0042987; GO:0043085; GO:0050673; GO:0051117; GO:0051402; GO:0070062; GO:0070765; GO:0070851; GO:0071277; GO:1900271; GO:1990926 44346 XM_044309770.1 7 0 6 80 246 NA NA NA NA NA NA 44347 XM_029348174.2 523 703 357 363 485 Q28DS0 1.03e-117 SUMO-activating enzyme subunit 1 (Ubiquitin-like 1-activating enzyme E1A) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) definitive hemopoiesis [GO:0060216]; hematopoietic stem cell homeostasis [GO:0061484]; protein sumoylation [GO:0016925] GO:0008022; GO:0008641; GO:0016925; GO:0031510; GO:0060216; GO:0061484 44348 XR_006395021.1 18 21 16 26 47 NA NA NA NA NA NA 44349 XM_029341092.2 110 172 32 114 42 NA NA NA NA NA NA 44350 XM_044320579.1 89 40 48 180 194 NA NA NA NA NA NA 44351 XM_044322524.1 500 452 181 928 801 Q8VE65 1.46e-55 Transcription initiation factor TFIID subunit 12 (Transcription initiation factor TFIID 20 kDa subunits) (TAFII-20) (TAFII20) Mus musculus (Mouse) DNA-templated transcription initiation [GO:0006352]; histone acetylation [GO:0016573]; histone H3 acetylation [GO:0043966]; monoubiquitinated histone deubiquitination [GO:0035521]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; mRNA transcription by RNA polymerase II [GO:0042789]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of DNA-templated transcription [GO:0006355]; regulation of RNA splicing [GO:0043484]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription initiation at RNA polymerase II promoter [GO:0006367] GO:0000124; GO:0003677; GO:0003713; GO:0005634; GO:0005669; GO:0006282; GO:0006352; GO:0006355; GO:0006357; GO:0006367; GO:0006468; GO:0016251; GO:0016573; GO:0017025; GO:0033276; GO:0035521; GO:0035522; GO:0042789; GO:0043484; GO:0043966; GO:0045893; GO:0045944; GO:0046695; GO:0046982; GO:0051091; GO:0051123; GO:0060261; GO:0140297 44352 XR_006391706.1 0 0 18 36 0 NA NA NA NA NA NA 44353 XM_044308162.1 89 58 19 164 66 NA NA NA NA NA NA 44354 XM_044327783.1 30 32 11 32 39 NA NA NA NA NA NA 44355 XR_006395817.1 735 1416 58 3064 878 NA NA NA NA NA NA 44356 XM_044307368.1 629 3 1034 445 160 P20072 4.9e-70 Annexin A7 (Annexin VII) (Annexin-7) (Synexin) Bos taurus (Bovine) NA GO:0005509; GO:0005544; GO:0005634; GO:0005737; GO:0042584 44357 XM_029334776.2 74 64 90 132 206 NA NA NA NA NA NA 44358 XM_044322396.1 160 39 101 27 0 Q96AY4 5.77e-94 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44359 XM_044322396.1 160 39 101 27 0 Q96AY4 2.37e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44360 XM_044322396.1 160 39 101 27 0 Q96AY4 2.65e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44361 XM_044322396.1 160 39 101 27 0 Q96AY4 2.13e-83 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44362 XM_044322396.1 160 39 101 27 0 Q96AY4 4.05e-83 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44363 XM_044322396.1 160 39 101 27 0 Q96AY4 9.36e-82 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44364 XM_044322396.1 160 39 101 27 0 Q96AY4 1.99e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44365 XM_029353767.2 281 29 208 933 697 NA NA NA NA NA NA 44366 XM_044313009.1 11 18 18 18 47 NA NA NA NA NA NA 44367 XR_006391747.1 173 9 28 159 54 NA NA NA NA NA NA 44368 XM_044321905.1 302 15 0 598 73 O34363 1.47e-24 Putative L-amino-acid oxidase YobN (EC 1.4.3.2) Bacillus subtilis (strain 168) amino acid catabolic process [GO:0009063] GO:0001716; GO:0009063; GO:0016491; GO:0046592 44369 XM_029348175.2 2428 2092 1741 1608 1131 Q969M7 7.1e-76 NEDD8-conjugating enzyme UBE2F (EC 2.3.2.32) (NEDD8 carrier protein UBE2F) (NEDD8 protein ligase UBE2F) (NEDD8-conjugating enzyme 2) (RING-type E3 NEDD8 transferase UBE2F) (Ubiquitin-conjugating enzyme E2 F) Homo sapiens (Human) post-translational protein modification [GO:0043687]; protein neddylation [GO:0045116] GO:0005524; GO:0005634; GO:0005829; GO:0019788; GO:0043687; GO:0045116; GO:0061654 44370 XM_029342615.2 15 283 18 79 183 G4WMX4 2.28e-25 RYamide receptor Tribolium castaneum (Red flour beetle) NA GO:0004983; GO:0005886 44371 XM_029351479.2 2891 3471 2325 2016 1900 NA NA NA NA NA NA 44372 XM_029327903.2 235 83 79 175 129 NA NA NA NA NA NA 44373 XR_006392129.1 8 3 0 646 1 NA NA NA NA NA NA 44374 XM_029337598.2 0 0 11 0 0 NA NA NA NA NA NA 44375 XM_029331692.2 122 126 116 101 177 B0V0U5 1.17e-30 Unhealthy ribosome biogenesis protein 2 homolog Danio rerio (Zebrafish) (Brachydanio rerio) regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of signal transduction by p53 class mediator [GO:1901796]; ribosome biogenesis [GO:0042254] GO:0005730; GO:0042254; GO:1901796; GO:1902036 44376 XM_029324524.2 90 20 113 52 141 K7VCB9 3.21e-58 Hydroxyethylthiazole kinase (EC 2.7.1.50) (4-methyl-5-beta-hydroxyethylthiazole kinase) (TH kinase) (Thz kinase) Zea mays (Maize) phosphorylation [GO:0016310]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]; thiamine salvage [GO:0036172] GO:0000287; GO:0004417; GO:0005524; GO:0009228; GO:0009229; GO:0016310; GO:0036172 44377 XM_044321476.1 21 34 43 59 42 NA NA NA NA NA NA 44378 XM_044328975.1 14 17 21 11 27 NA NA NA NA NA NA 44379 XM_029338469.2 1034 1022 493 678 588 NA NA NA NA NA NA 44380 XM_044313421.1 4 0 0 2 8 NA NA NA NA NA NA 44381 XM_029335107.2 3318 2286 1653 3407 3532 P55884 0 Eukaryotic translation initiation factor 3 subunit B (eIF3b) (Eukaryotic translation initiation factor 3 subunit 9) (Prt1 homolog) (hPrt1) (eIF-3-eta) (eIF3 p110) (eIF3 p116) Homo sapiens (Human) formation of cytoplasmic translation initiation complex [GO:0001732]; IRES-dependent viral translational initiation [GO:0075522]; regulation of translational initiation [GO:0006446]; translational initiation [GO:0006413]; viral translational termination-reinitiation [GO:0075525] GO:0001732; GO:0003723; GO:0003743; GO:0005829; GO:0005852; GO:0006413; GO:0006446; GO:0010494; GO:0016282; GO:0031369; GO:0033290; GO:0045202; GO:0060090; GO:0070062; GO:0071541; GO:0075522; GO:0075525 44382 XM_044313474.1 13 7 23 5 46 NA NA NA NA NA NA 44383 XM_029348493.2 81 154 18 10 184 NA NA NA NA NA NA 44384 XM_029357668.2 1236 610 573 499 264 Q63424 2.55e-167 Solute carrier family 15 member 2 (Kidney H(+)/peptide cotransporter) (Oligopeptide transporter, kidney isoform) (Peptide transporter 2) Rattus norvegicus (Rat) dipeptide import across plasma membrane [GO:0140206]; dipeptide transport [GO:0042938]; innate immune response [GO:0045087]; oligopeptide transmembrane transport [GO:0035672]; oligopeptide transport [GO:0006857]; peptidoglycan transport [GO:0015835]; protein transport [GO:0015031]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424]; renal absorption [GO:0070293]; transmembrane transport [GO:0055085]; xenobiotic transport [GO:0042908] GO:0005886; GO:0006857; GO:0015031; GO:0015333; GO:0015334; GO:0015835; GO:0016020; GO:0016324; GO:0022857; GO:0035672; GO:0042908; GO:0042938; GO:0045087; GO:0055085; GO:0070293; GO:0070424; GO:0071916; GO:0140206 44385 XM_029340941.2 85 51 107 147 0 Q9TRC7 3.11e-173 Amiloride-sensitive amine oxidase [copper-containing] (DAO) (Diamine oxidase) (EC 1.4.3.22) (Amiloride-binding protein 1) (Amine oxidase copper domain-containing protein 1) (Histaminase) Sus scrofa (Pig) amine metabolic process [GO:0009308]; cellular response to azide [GO:0097185]; cellular response to copper ion [GO:0071280]; cellular response to copper ion starvation [GO:0035874]; cellular response to histamine [GO:0071420]; putrescine metabolic process [GO:0009445]; response to antibiotic [GO:0046677] GO:0005507; GO:0005509; GO:0005615; GO:0005886; GO:0005923; GO:0008131; GO:0008201; GO:0008270; GO:0009308; GO:0009445; GO:0035874; GO:0042803; GO:0044877; GO:0046677; GO:0048038; GO:0052597; GO:0052598; GO:0052599; GO:0052600; GO:0070062; GO:0071280; GO:0071420; GO:0097185 44386 XM_044317515.1 25 2 7 15 35 Q80XJ3 3.13e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 44387 XM_044323925.1 13 73 19 40 22 P0C7P0 1.98e-23 CDGSH iron-sulfur domain-containing protein 3, mitochondrial (MitoNEET-related protein 2) (Miner2) (Mitochondrial inner NEET protein) (MiNT) Homo sapiens (Human) protein maturation by [2Fe-2S] cluster transfer [GO:0106034] GO:0005739; GO:0046872; GO:0051537; GO:0106034 44388 XM_029338499.2 7 21 7 29 18 NA NA NA NA NA NA 44389 XM_044325764.1 14 6 2 6 8 NA NA NA NA NA NA 44390 XM_044312493.1 89 154 64 496 42 NA NA NA NA NA NA 44391 XM_029334193.2 193 28 62 64 88 Q5R4A6 2.89e-40 Archaemetzincin-2 (EC 3.4.-.-) (Archeobacterial metalloproteinase-like protein 2) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) proteolysis [GO:0006508] GO:0006508; GO:0008237; GO:0046872 44392 XM_029328899.2 1518 1416 1125 1791 1525 Q9Y547 1.35e-39 Intraflagellar transport protein 25 homolog (Heat shock protein beta-11) (Hspb11) (Placental protein 25) (PP25) Homo sapiens (Human) cell differentiation [GO:0030154]; cilium assembly [GO:0060271]; heart development [GO:0007507]; intraciliary anterograde transport [GO:0035720]; kidney development [GO:0001822]; left/right axis specification [GO:0070986]; lung development [GO:0030324]; protein transport [GO:0015031]; skeletal system development [GO:0001501]; smoothened signaling pathway [GO:0007224]; spermatogenesis [GO:0007283] GO:0001501; GO:0001822; GO:0005813; GO:0005929; GO:0007224; GO:0007283; GO:0007507; GO:0015031; GO:0030154; GO:0030324; GO:0030992; GO:0035720; GO:0046872; GO:0060271; GO:0070986; GO:0097542 44393 XR_006393738.1 385 97 0 0 294 NA NA NA NA NA NA 44394 XM_044316412.1 67 59 99 106 89 Q9EQD2 2.11e-44 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 44395 XM_044316412.1 67 59 99 106 89 Q9EQD2 9e-39 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 44396 XM_029333059.2 1809 968 905 1388 1191 Q8IUS5 3.34e-92 Epoxide hydrolase 4 (EC 3.3.-.-) (Abhydrolase domain-containing protein 7) (Epoxide hydrolase-related protein) Homo sapiens (Human) NA GO:0016020; GO:0016787 44397 XM_029329477.2 4450 3861 2543 3572 4206 Q9NUQ9 8.01e-146 CYFIP-related Rac1 interactor B (L1) Homo sapiens (Human) cellular response to molecule of bacterial origin [GO:0071219]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of small GTPase mediated signal transduction [GO:0051058]; positive regulation of memory T cell activation [GO:2000568]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of type II interferon production [GO:0032729]; regulation of cell migration [GO:0030334]; regulation of chemotaxis [GO:0050920]; regulation of establishment of cell polarity [GO:2000114]; regulation of mitochondrial fission [GO:0090140] GO:0001916; GO:0005576; GO:0005739; GO:0005929; GO:0016020; GO:0023030; GO:0030334; GO:0030837; GO:0031093; GO:0031267; GO:0032729; GO:0050870; GO:0050920; GO:0051058; GO:0070062; GO:0071219; GO:0090140; GO:2000114; GO:2000568 44398 XM_044313290.1 6 0 4 0 2 NA NA NA NA NA NA 44399 XM_044307986.1 105 51 572 138 665 P0CI65 2.07e-46 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 44400 XM_044307986.1 105 51 572 138 665 P0CI65 1.42e-45 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 44401 XM_044323514.1 226 182 271 145 144 Q9LP24 1.79e-21 Probable leucine-rich repeat receptor-like protein kinase At1g35710 (EC 2.7.11.1) Arabidopsis thaliana (Mouse-ear cress) hormone-mediated signaling pathway [GO:0009755]; protein phosphorylation [GO:0006468] GO:0004674; GO:0005524; GO:0005886; GO:0006468; GO:0009755; GO:0106310 44402 XM_029349444.2 257 203 178 309 271 NA NA NA NA NA NA 44403 XR_006396020.1 34 0 0 0 0 NA NA NA NA NA NA 44404 XM_029336433.2 0 35 0 34 93 Q6ZNB5 6.18e-28 Protein XNDC1N (XRCC1 N-terminal domain-containing 1 N-terminal like) Homo sapiens (Human) single strand break repair [GO:0000012] GO:0000012; GO:0003684; GO:0005694; GO:0005730 44405 XM_044327823.1 0 14 0 6 0 NA NA NA NA NA NA 44406 XR_006398072.1 989 636 474 2718 1092 O60303 0 Katanin-interacting protein Homo sapiens (Human) cerebrospinal fluid circulation [GO:0090660] GO:0005615; GO:0005737; GO:0005856; GO:0042995; GO:0090660 44407 XM_044315779.1 31 40 28 60 139 NA NA NA NA NA NA 44408 XM_044317894.1 0 0 0 0 35 NA NA NA NA NA NA 44409 XR_006396067.1 292 589 381 505 460 NA NA NA NA NA NA 44410 XM_044308581.1 2572 2850 1984 1196 1879 P42678 1.83e-40 Eukaryotic translation initiation factor eIF1 (Protein translation factor SUI1 homolog) Anopheles gambiae (African malaria mosquito) NA GO:0003723; GO:0003743; GO:0016282; GO:0043024 44411 XR_006396499.1 0 5 1 0 65 NA NA NA NA NA NA 44412 XM_029345822.2 774 807 289 401 308 NA NA NA NA NA NA 44413 XM_029325338.2 145 45 148 70 92 NA NA NA NA NA NA 44414 XR_003824972.2 25 13 46 28 319 NA NA NA NA NA NA 44415 XM_029331069.2 2197 4907 2063 3622 1993 Q6AXJ7 3e-21 Protein FAM199X Danio rerio (Zebrafish) (Brachydanio rerio) NA NA 44416 XM_029332249.2 31 0 66 73 0 Q805E5 4.03e-77 Carbohydrate sulfotransferase 14 (EC 2.8.2.-) (Dermatan 4-sulfotransferase 1) (D4ST-1) (zD4ST-1) Danio rerio (Zebrafish) (Brachydanio rerio) carbohydrate biosynthetic process [GO:0016051]; dermatan sulfate proteoglycan metabolic process [GO:0050655] GO:0000139; GO:0001537; GO:0008146; GO:0016051; GO:0050655 44417 XR_003825153.2 0 0 0 4 13 NA NA NA NA NA NA 44418 XM_044320999.1 0 154 0 5 0 Q8R3S6 0 Exocyst complex component 1 (Exocyst complex component Sec3) Mus musculus (Mouse) embryo implantation [GO:0007566]; exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; membrane fission [GO:0090148]; mitotic cytokinesis [GO:0000281]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of protein secretion [GO:0050714]; protein transport [GO:0015031]; vesicle docking involved in exocytosis [GO:0006904]; vesicle tethering involved in exocytosis [GO:0090522] GO:0000145; GO:0000281; GO:0005546; GO:0005737; GO:0005886; GO:0006887; GO:0006893; GO:0006904; GO:0007566; GO:0015031; GO:0048015; GO:0048471; GO:0050714; GO:0090148; GO:0090522; GO:0090543; GO:0098592 44419 XM_029332984.2 33 125 54 55 182 Q92667 1.94e-38 A-kinase anchor protein 1, mitochondrial (A-kinase anchor protein 149 kDa) (AKAP 149) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Protein kinase A-anchoring protein 1) (PRKA1) (Spermatid A-kinase anchor protein 84) (S-AKAP84) Homo sapiens (Human) antiviral innate immune response [GO:0140374]; apoptotic process [GO:0006915] GO:0003723; GO:0005739; GO:0005741; GO:0005829; GO:0006915; GO:0016020; GO:0034237; GO:0140374 44420 XM_044318784.1 0 1 0 0 11 NA NA NA NA NA NA 44421 XR_006391780.1 28 42 31 92 83 NA NA NA NA NA NA 44422 XM_029324137.2 146 30 43 229 118 NA NA NA NA NA NA 44423 XM_029348954.2 2592 2789 1511 2644 1289 Q9H4K1 3.11e-81 RIB43A-like with coiled-coils protein 2 Homo sapiens (Human) NA GO:0005634; GO:0005879 44424 XM_044323512.1 0 15 0 0 6 NA NA NA NA NA NA 44425 XM_029336607.2 0 0 0 0 7 NA NA NA NA NA NA 44426 XM_029329352.2 154 0 106 0 49 O08873 5.87e-159 MAP kinase-activating death domain protein (Rab3 GDP/GTP exchange factor) (RabGEF) (Rab3 GDP/GTP exchange protein) (RabGEP) Rattus norvegicus (Rat) anterograde synaptic vesicle transport [GO:0048490]; execution phase of apoptosis [GO:0097194]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of growth hormone secretion [GO:0060125]; negative regulation of pancreatic amylase secretion [GO:1902277]; positive regulation of MAPK cascade [GO:0043410]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of extrinsic apoptotic signaling pathway [GO:2001236]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of Rab protein signal transduction [GO:0032483] GO:0005085; GO:0005634; GO:0005829; GO:0005886; GO:0008021; GO:0016020; GO:0030424; GO:0032483; GO:0042981; GO:0043410; GO:0045202; GO:0048490; GO:0051726; GO:0060125; GO:0097194; GO:1902041; GO:1902277; GO:1904115; GO:2001234; GO:2001236 44427 XM_029329352.2 154 0 106 0 49 O08873 1.29e-123 MAP kinase-activating death domain protein (Rab3 GDP/GTP exchange factor) (RabGEF) (Rab3 GDP/GTP exchange protein) (RabGEP) Rattus norvegicus (Rat) anterograde synaptic vesicle transport [GO:0048490]; execution phase of apoptosis [GO:0097194]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of growth hormone secretion [GO:0060125]; negative regulation of pancreatic amylase secretion [GO:1902277]; positive regulation of MAPK cascade [GO:0043410]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of extrinsic apoptotic signaling pathway [GO:2001236]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of Rab protein signal transduction [GO:0032483] GO:0005085; GO:0005634; GO:0005829; GO:0005886; GO:0008021; GO:0016020; GO:0030424; GO:0032483; GO:0042981; GO:0043410; GO:0045202; GO:0048490; GO:0051726; GO:0060125; GO:0097194; GO:1902041; GO:1902277; GO:1904115; GO:2001234; GO:2001236 44428 XM_029345760.2 163 52 85 79 154 Q9BYN7 5.32e-38 Zinc finger protein 341 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0000978; GO:0000981; GO:0001216; GO:0003677; GO:0005634; GO:0006355; GO:0046872 44429 XM_029358104.2 59 46 77 37 253 NA NA NA NA NA NA 44430 XM_044314431.1 1 3 0 0 9 Q09575 1.35e-43 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 44431 XM_029347286.2 7 0 18 4 45 NA NA NA NA NA NA 44432 XM_029330282.2 97 50 21 9 36 Q8NBA8 4.34e-56 tRNA-uridine aminocarboxypropyltransferase 2 (EC 2.5.1.25) (DTW domain-containing protein 2) Homo sapiens (Human) tRNA modification [GO:0006400] GO:0005634; GO:0005737; GO:0006400; GO:0016432 44433 XM_044326886.1 7 3 19 38 37 NA NA NA NA NA NA 44434 XM_044325275.1 0 0 0 14 27 NA NA NA NA NA NA 44435 XR_006391787.1 24 2 74 72 84 NA NA NA NA NA NA 44436 XM_044323685.1 0 0 0 0 122 NA NA NA NA NA NA 44437 XR_003823978.2 75 12 84 40 217 NA NA NA NA NA NA 44438 XR_006393959.1 3 0 0 8 0 NA NA NA NA NA NA 44439 XM_044323701.1 26 0 11 0 33 Q8NDA2 4.38e-40 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 44440 XM_044323701.1 26 0 11 0 33 Q8NDA2 5.24e-30 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 44441 XM_044323701.1 26 0 11 0 33 Q8NDA2 8.4e-30 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 44442 XM_044323701.1 26 0 11 0 33 Q8NDA2 2.01e-29 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 44443 XM_044323701.1 26 0 11 0 33 Q8NDA2 2.16e-29 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 44444 XM_044323701.1 26 0 11 0 33 Q8NDA2 3.75e-29 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 44445 XM_044323701.1 26 0 11 0 33 Q8NDA2 4.09e-29 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 44446 XM_044323701.1 26 0 11 0 33 Q8NDA2 7.53e-29 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 44447 XM_044323701.1 26 0 11 0 33 Q8NDA2 1.09e-28 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 44448 XM_044323701.1 26 0 11 0 33 Q8NDA2 2.02e-28 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 44449 XM_044323701.1 26 0 11 0 33 Q8NDA2 1.55e-27 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 44450 XM_044323701.1 26 0 11 0 33 Q8NDA2 1.65e-27 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 44451 XM_044323701.1 26 0 11 0 33 Q8NDA2 3.01e-27 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 44452 XM_044323701.1 26 0 11 0 33 Q8NDA2 5.29e-27 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 44453 XM_044323701.1 26 0 11 0 33 Q8NDA2 6.4e-27 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 44454 XM_044323701.1 26 0 11 0 33 Q8NDA2 2.53e-26 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 44455 XM_044323701.1 26 0 11 0 33 Q8NDA2 5.91e-26 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 44456 XM_044323701.1 26 0 11 0 33 Q8NDA2 5.87e-25 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 44457 XM_044323701.1 26 0 11 0 33 Q8NDA2 2.49e-24 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 44458 XM_044323701.1 26 0 11 0 33 Q8NDA2 4.18e-24 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 44459 XM_044323701.1 26 0 11 0 33 Q8NDA2 1.46e-22 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 44460 XM_044323701.1 26 0 11 0 33 Q8NDA2 3.94e-21 Hemicentin-2 Homo sapiens (Human) axon guidance [GO:0007411]; cell adhesion [GO:0007155] GO:0005509; GO:0005615; GO:0007155; GO:0007411; GO:0031012; GO:0032154; GO:0062023 44461 XM_029340972.2 200 28 81 50 60 NA NA NA NA NA NA 44462 XM_029356277.2 1679 1005 910 2062 211 Q0DXS3 2.14e-145 Probable RNA-dependent RNA polymerase 1 (OsRDR1) (EC 2.7.7.48) Oryza sativa subsp. japonica (Rice) positive regulation of post-transcriptional gene silencing [GO:0060148]; response to salicylic acid [GO:0009751]; response to virus [GO:0009615]; siRNA processing [GO:0030422]; wax biosynthetic process [GO:0010025] GO:0003723; GO:0003968; GO:0009615; GO:0009751; GO:0010025; GO:0030422; GO:0031380; GO:0060148 44463 XM_029340764.2 899 1047 723 907 578 NA NA NA NA NA NA 44464 XM_044326868.1 0 0 0 29 0 NA NA NA NA NA NA 44465 XM_044306810.1 1893 1823 1396 1529 2067 Q640S1 1.15e-75 Zinc transporter ZIP9 (Solute carrier family 39 member 9) (Zrt- and Irt-like protein 9) (ZIP-9) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) bicellular tight junction assembly [GO:0070830]; cellular zinc ion homeostasis [GO:0006882]; regulation of cellular response to testosterone stimulus [GO:2000654]; regulation of vascular endothelial cell proliferation [GO:1905562]; zinc ion transmembrane transport [GO:0071577] GO:0004930; GO:0005385; GO:0005497; GO:0005634; GO:0005739; GO:0005802; GO:0005886; GO:0006882; GO:0022883; GO:0031966; GO:0048471; GO:0070830; GO:0071577; GO:1905562; GO:2000654 44466 XM_044309664.1 88 105 9 0 10 Q8NB78 0 Lysine-specific histone demethylase 2 (EC 1.14.99.66) (Flavin-containing amine oxidase domain-containing protein 1) (Lysine-specific histone demethylase 1B) Homo sapiens (Human) DNA methylation involved in gamete generation [GO:0043046]; histone H3-K4 demethylation [GO:0034720]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA methylation [GO:0044030]; regulation of gene expression by genomic imprinting [GO:0006349] GO:0000122; GO:0000786; GO:0003682; GO:0005634; GO:0005654; GO:0006349; GO:0008270; GO:0016491; GO:0032452; GO:0034720; GO:0042393; GO:0043046; GO:0044030; GO:0045944; GO:0050660; GO:0071949; GO:0140682 44467 XM_044317793.1 6 1 0 1 0 P55809 1.48e-179 Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial (SCOT) (EC 2.8.3.5) (3-oxoacid CoA-transferase 1) (Somatic-type succinyl-CoA:3-oxoacid CoA-transferase) (SCOT-s) (Succinyl-CoA:3-oxoacid CoA transferase) Homo sapiens (Human) adipose tissue development [GO:0060612]; brain development [GO:0007420]; cellular ketone body metabolic process [GO:0046950]; heart development [GO:0007507]; ketone body catabolic process [GO:0046952]; ketone catabolic process [GO:0042182]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; response to activity [GO:0014823]; response to ethanol [GO:0045471]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; response to starvation [GO:0042594]; response to xenobiotic stimulus [GO:0009410] GO:0005739; GO:0005759; GO:0007420; GO:0007507; GO:0007584; GO:0008260; GO:0008410; GO:0009410; GO:0009725; GO:0014823; GO:0035774; GO:0042182; GO:0042594; GO:0042802; GO:0045471; GO:0046950; GO:0046952; GO:0060612 44468 XM_044317793.1 6 1 0 1 0 P55809 1.41e-27 Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial (SCOT) (EC 2.8.3.5) (3-oxoacid CoA-transferase 1) (Somatic-type succinyl-CoA:3-oxoacid CoA-transferase) (SCOT-s) (Succinyl-CoA:3-oxoacid CoA transferase) Homo sapiens (Human) adipose tissue development [GO:0060612]; brain development [GO:0007420]; cellular ketone body metabolic process [GO:0046950]; heart development [GO:0007507]; ketone body catabolic process [GO:0046952]; ketone catabolic process [GO:0042182]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; response to activity [GO:0014823]; response to ethanol [GO:0045471]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; response to starvation [GO:0042594]; response to xenobiotic stimulus [GO:0009410] GO:0005739; GO:0005759; GO:0007420; GO:0007507; GO:0007584; GO:0008260; GO:0008410; GO:0009410; GO:0009725; GO:0014823; GO:0035774; GO:0042182; GO:0042594; GO:0042802; GO:0045471; GO:0046950; GO:0046952; GO:0060612 44469 XM_044317137.1 0 0 0 7 2 NA NA NA NA NA NA 44470 XR_006394570.1 219 44 0 1 29 NA NA NA NA NA NA 44471 XM_044321120.1 27 0 58 1 40 NA NA NA NA NA NA 44472 XM_029354797.2 171 98 292 149 441 NA NA NA NA NA NA 44473 XM_029349540.2 653 617 359 869 777 Q6PAM1 4.65e-81 Alpha-taxilin Mus musculus (Mouse) B cell activation [GO:0042113]; exocytosis [GO:0006887] GO:0005737; GO:0006887; GO:0019905; GO:0042113 44474 XM_029328330.2 21 13 28 26 137 NA NA NA NA NA NA 44475 XM_044317264.1 19 0 0 47 24 Q9WYP5 2.7e-61 Myo-inositol 2-dehydrogenase (EC 1.1.1.18) Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) inositol metabolic process [GO:0006020]; NADPH regeneration [GO:0006740] GO:0000166; GO:0006020; GO:0006740; GO:0016491; GO:0050112 44476 XM_044322473.1 0 0 0 0 59 C6KFA3 2.19e-36 Adhesion G-protein coupled receptor G6 (G-protein coupled receptor 126) [Cleaved into: ADGRG6 N-terminal fragment (ADGRG6-NTF); ADGRG6 C-terminal fragment (ADGRG6-CTF)] Danio rerio (Zebrafish) (Brachydanio rerio) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cAMP-mediated signaling [GO:0019933]; cell surface receptor signaling pathway [GO:0007166]; ear development [GO:0043583]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; heart trabecula formation [GO:0060347]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; myelination of posterior lateral line nerve axons [GO:0048932]; ossification [GO:0001503]; peripheral nervous system myelin formation [GO:0032290]; regulation of sprouting angiogenesis [GO:1903670]; Schwann cell differentiation [GO:0014037]; semicircular canal fusion [GO:0060879] GO:0001503; GO:0004930; GO:0005518; GO:0005886; GO:0007005; GO:0007166; GO:0007186; GO:0007189; GO:0007507; GO:0014037; GO:0019933; GO:0022011; GO:0032290; GO:0042552; GO:0043236; GO:0043583; GO:0048932; GO:0050840; GO:0060347; GO:0060879; GO:1903670 44477 XR_006393074.1 41 2 25 5 151 NA NA NA NA NA NA 44478 XM_029353279.2 345 170 186 392 383 Q9JLZ3 4.75e-105 Methylglutaconyl-CoA hydratase, mitochondrial (3-MG-CoA hydratase) (EC 4.2.1.18) (AU-specific RNA-binding enoyl-CoA hydratase) (AU-binding enoyl-CoA hydratase) (muAUH) (Itaconyl-CoA hydratase) (EC 4.2.1.56) Mus musculus (Mouse) fatty acid beta-oxidation [GO:0006635]; leucine catabolic process [GO:0006552] GO:0003723; GO:0003730; GO:0004300; GO:0004490; GO:0005739; GO:0006552; GO:0006635; GO:0050011 44479 XM_029350727.2 503 481 510 706 679 Q7JW12 5.93e-65 Thioredoxin-related transmembrane protein 2 homolog (Thioredoxin domain-containing protein 14 homolog) Drosophila melanogaster (Fruit fly) NA GO:0015036; GO:0016020; GO:0043227 44480 XM_044308983.1 53 0 75 117 0 Q60HG9 0 Carnitine O-palmitoyltransferase 2, mitochondrial (EC 2.3.1.21) (Carnitine palmitoyltransferase II) (CPT II) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) carnitine metabolic process [GO:0009437]; fatty acid beta-oxidation [GO:0006635]; long-chain fatty acid metabolic process [GO:0001676] GO:0001676; GO:0004095; GO:0005743; GO:0006635; GO:0008458; GO:0009437; GO:0016746 44481 XM_044324266.1 0 8 0 387 178 Q9VBW3 4.14e-82 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 44482 XM_029333250.2 597 674 437 844 634 Q9D0S9 5.64e-42 Adenosine 5'-monophosphoramidase HINT2 (EC 3.9.1.-) (HINT-3) (Histidine triad nucleotide-binding protein 2, mitochondrial) (HINT-2) Mus musculus (Mouse) apoptotic process [GO:0006915]; lipid catabolic process [GO:0016042]; negative regulation of peptidyl-lysine acetylation [GO:2000757]; steroid biosynthetic process [GO:0006694] GO:0000166; GO:0005737; GO:0005739; GO:0006694; GO:0006915; GO:0016042; GO:0016787; GO:0043530; GO:2000757 44483 XM_029351740.2 17 85 9 148 37 P17244 0 Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (EC 1.2.1.12) (Peptidyl-cysteine S-nitrosylase GAPDH) (EC 2.6.99.-) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]; innate immune response [GO:0045087]; microtubule cytoskeleton organization [GO:0000226]; neuron apoptotic process [GO:0051402]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of type I interferon production [GO:0032481]; protein stabilization [GO:0050821]; regulation of translation [GO:0006417] GO:0000226; GO:0004365; GO:0005634; GO:0005737; GO:0005829; GO:0006006; GO:0006096; GO:0006417; GO:0008017; GO:0015630; GO:0032481; GO:0035605; GO:0035606; GO:0043123; GO:0045087; GO:0050661; GO:0050821; GO:0051287; GO:0051402; GO:0097452 44484 XM_044309495.1 41 16 74 25 176 NA NA NA NA NA NA 44485 XM_029346600.2 1541 1543 1169 849 318 NA NA NA NA NA NA 44486 XM_029348503.2 1 3 0 11 1 NA NA NA NA NA NA 44487 XM_029344272.2 26 8 38 33 6 NA NA NA NA NA NA 44488 XR_003822975.2 0 0 0 6 5 NA NA NA NA NA NA 44489 XM_044314575.1 332 205 105 170 279 Q80XJ3 4.34e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 44490 XM_044313258.1 514 273 395 594 539 NA NA NA NA NA NA 44491 XR_006392428.1 342 104 14 180 1188 NA NA NA NA NA NA 44492 XR_006397925.1 0 15 2 0 0 NA NA NA NA NA NA 44493 XM_044309351.1 0 41 0 0 0 NA NA NA NA NA NA 44494 XM_029328361.2 1355 2435 1044 2057 987 Q9JJ80 2.52e-113 Ribosome production factor 2 homolog (Brix domain-containing protein 1) (Ribosome biogenesis protein RPF2 homolog) Mus musculus (Mouse) maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; protein localization to nucleolus [GO:1902570]; regulation of signal transduction by p53 class mediator [GO:1901796]; ribosomal large subunit assembly [GO:0000027]; ribosomal large subunit biogenesis [GO:0042273] GO:0000027; GO:0000463; GO:0000981; GO:0005654; GO:0005694; GO:0005730; GO:0008097; GO:0019843; GO:0042273; GO:1901796; GO:1902570 44495 XM_044307122.1 0 18 0 0 0 Q9U6Y6 1.11e-106 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 44496 XR_006395130.1 388 524 188 419 1047 NA NA NA NA NA NA 44497 XM_044307879.1 311 240 176 431 260 Q96AY4 2.58e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44498 XM_044307879.1 311 240 176 431 260 Q96AY4 6.84e-89 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44499 XM_044307879.1 311 240 176 431 260 Q96AY4 2.54e-88 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44500 XM_044307879.1 311 240 176 431 260 Q96AY4 3.34e-88 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44501 XM_044307879.1 311 240 176 431 260 Q96AY4 6.99e-88 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44502 XM_044307879.1 311 240 176 431 260 Q96AY4 8.36e-88 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44503 XM_044307879.1 311 240 176 431 260 Q96AY4 6.06e-79 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44504 XM_044307879.1 311 240 176 431 260 Q96AY4 1.14e-61 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44505 XM_044307879.1 311 240 176 431 260 Q96AY4 5.76e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44506 XM_029331239.2 66 89 47 80 63 NA NA NA NA NA NA 44507 XM_044317889.1 141 230 101 142 45 Q9VUL9 1.3e-38 Glycoprotein 3-alpha-L-fucosyltransferase A (EC 2.4.1.214) (Core alpha-(1,3)-fucosyltransferase) Drosophila melanogaster (Fruit fly) fucosylation [GO:0036065]; N-glycan fucosylation [GO:0036071]; nervous system development [GO:0007399]; protein glycosylation [GO:0006486] GO:0005797; GO:0006486; GO:0007399; GO:0008417; GO:0018392; GO:0032580; GO:0036065; GO:0036071; GO:0046920 44508 XM_029340425.2 694 440 416 669 927 Q8BJM3 4.36e-38 Coiled-coil domain-containing protein R3HCC1L (Growth inhibition and differentiation-related protein 88 homolog) (R3H and coiled-coil domain-containing protein 1-like) Mus musculus (Mouse) NA GO:0035145 44509 XM_044326017.1 2574 2973 2074 2001 2195 Q9UKV8 0 Protein argonaute-2 (Argonaute2) (hAgo2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (PAZ Piwi domain protein) (PPD) (Protein slicer) Homo sapiens (Human) miRNA metabolic process [GO:0010586]; miRNA processing [GO:0035196]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; miRNA-mediated gene silencing by mRNA destabilization [GO:0035279]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; negative regulation of translational initiation [GO:0045947]; positive regulation of angiogenesis [GO:0045766]; positive regulation of gene expression [GO:0010628]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of trophoblast cell migration [GO:1901165]; post-embryonic development [GO:0009791]; pre-miRNA processing [GO:0031054]; RISC complex assembly [GO:0070922]; RNA secondary structure unwinding [GO:0010501]; RNA-mediated gene silencing [GO:0031047]; RNA-mediated post-transcriptional gene silencing [GO:0035194]; siRNA processing [GO:0030422]; siRNA-mediated gene silencing by mRNA destabilization [GO:0090625]; translation [GO:0006412] GO:0000340; GO:0000932; GO:0000993; GO:0001046; GO:0003723; GO:0003725; GO:0003727; GO:0003743; GO:0004521; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005844; GO:0005845; GO:0006412; GO:0008022; GO:0009791; GO:0010501; GO:0010586; GO:0010628; GO:0016020; GO:0016442; GO:0030422; GO:0030425; GO:0031047; GO:0031054; GO:0035194; GO:0035196; GO:0035197; GO:0035198; GO:0035278; GO:0035279; GO:0036464; GO:0042985; GO:0045766; GO:0045944; GO:0045947; GO:0046872; GO:0060213; GO:0070062; GO:0070551; GO:0070578; GO:0070922; GO:0090624; GO:0090625; GO:0098808; GO:1900153; GO:1901165; GO:1990904 44510 XM_044308727.1 74 58 56 147 154 NA NA NA NA NA NA 44511 XM_029336063.2 136 34 151 219 196 Q6DKP5 6.67e-164 WD repeat-containing protein 13 Pan troglodytes (Chimpanzee) NA GO:0005634; GO:1990841 44512 XM_044321732.1 289 73 71 75 237 Q6JHU9 0 Histone lysine acetyltransferase CREBBP (EC 2.3.1.48) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-) Rattus norvegicus (Rat) behavioral response to cocaine [GO:0048148]; cell population proliferation [GO:0008283]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to UV [GO:0034644]; cellular response to virus [GO:0098586]; face morphogenesis [GO:0060325]; germ-line stem cell population maintenance [GO:0030718]; histone acetylation [GO:0016573]; histone glutamine methylation [GO:1990258]; histone modification [GO:0016570]; long-term memory [GO:0007616]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription by RNA polymerase I [GO:0016479]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral process [GO:0048525]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; regulation of DNA-templated transcription [GO:0006355]; response to interleukin-1 [GO:0070555]; response to ischemia [GO:0002931]; rhythmic process [GO:0048511] GO:0000122; GO:0000123; GO:0000785; GO:0000940; GO:0000977; GO:0001093; GO:0001223; GO:0002039; GO:0002931; GO:0003677; GO:0003682; GO:0003684; GO:0003713; GO:0003714; GO:0004402; GO:0005634; GO:0005654; GO:0005667; GO:0005737; GO:0006355; GO:0006473; GO:0007616; GO:0008140; GO:0008270; GO:0008283; GO:0010628; GO:0016407; GO:0016479; GO:0016570; GO:0016573; GO:0016604; GO:0018076; GO:0019904; GO:0030511; GO:0030718; GO:0031490; GO:0031648; GO:0032688; GO:0032793; GO:0032991; GO:0034644; GO:0035729; GO:0042975; GO:0043426; GO:0045893; GO:0045944; GO:0046332; GO:0048148; GO:0048511; GO:0048525; GO:0060090; GO:0060325; GO:0060355; GO:0060999; GO:0061629; GO:0061733; GO:0070555; GO:0090575; GO:0097718; GO:0098586; GO:0140297; GO:1900087; GO:1901224; GO:1990258 44513 XM_044321732.1 289 73 71 75 237 Q6JHU9 8.15e-40 Histone lysine acetyltransferase CREBBP (EC 2.3.1.48) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-) Rattus norvegicus (Rat) behavioral response to cocaine [GO:0048148]; cell population proliferation [GO:0008283]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to UV [GO:0034644]; cellular response to virus [GO:0098586]; face morphogenesis [GO:0060325]; germ-line stem cell population maintenance [GO:0030718]; histone acetylation [GO:0016573]; histone glutamine methylation [GO:1990258]; histone modification [GO:0016570]; long-term memory [GO:0007616]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription by RNA polymerase I [GO:0016479]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral process [GO:0048525]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; regulation of DNA-templated transcription [GO:0006355]; response to interleukin-1 [GO:0070555]; response to ischemia [GO:0002931]; rhythmic process [GO:0048511] GO:0000122; GO:0000123; GO:0000785; GO:0000940; GO:0000977; GO:0001093; GO:0001223; GO:0002039; GO:0002931; GO:0003677; GO:0003682; GO:0003684; GO:0003713; GO:0003714; GO:0004402; GO:0005634; GO:0005654; GO:0005667; GO:0005737; GO:0006355; GO:0006473; GO:0007616; GO:0008140; GO:0008270; GO:0008283; GO:0010628; GO:0016407; GO:0016479; GO:0016570; GO:0016573; GO:0016604; GO:0018076; GO:0019904; GO:0030511; GO:0030718; GO:0031490; GO:0031648; GO:0032688; GO:0032793; GO:0032991; GO:0034644; GO:0035729; GO:0042975; GO:0043426; GO:0045893; GO:0045944; GO:0046332; GO:0048148; GO:0048511; GO:0048525; GO:0060090; GO:0060325; GO:0060355; GO:0060999; GO:0061629; GO:0061733; GO:0070555; GO:0090575; GO:0097718; GO:0098586; GO:0140297; GO:1900087; GO:1901224; GO:1990258 44514 XM_044321732.1 289 73 71 75 237 Q6JHU9 1.3e-28 Histone lysine acetyltransferase CREBBP (EC 2.3.1.48) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-) Rattus norvegicus (Rat) behavioral response to cocaine [GO:0048148]; cell population proliferation [GO:0008283]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to UV [GO:0034644]; cellular response to virus [GO:0098586]; face morphogenesis [GO:0060325]; germ-line stem cell population maintenance [GO:0030718]; histone acetylation [GO:0016573]; histone glutamine methylation [GO:1990258]; histone modification [GO:0016570]; long-term memory [GO:0007616]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription by RNA polymerase I [GO:0016479]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral process [GO:0048525]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; regulation of DNA-templated transcription [GO:0006355]; response to interleukin-1 [GO:0070555]; response to ischemia [GO:0002931]; rhythmic process [GO:0048511] GO:0000122; GO:0000123; GO:0000785; GO:0000940; GO:0000977; GO:0001093; GO:0001223; GO:0002039; GO:0002931; GO:0003677; GO:0003682; GO:0003684; GO:0003713; GO:0003714; GO:0004402; GO:0005634; GO:0005654; GO:0005667; GO:0005737; GO:0006355; GO:0006473; GO:0007616; GO:0008140; GO:0008270; GO:0008283; GO:0010628; GO:0016407; GO:0016479; GO:0016570; GO:0016573; GO:0016604; GO:0018076; GO:0019904; GO:0030511; GO:0030718; GO:0031490; GO:0031648; GO:0032688; GO:0032793; GO:0032991; GO:0034644; GO:0035729; GO:0042975; GO:0043426; GO:0045893; GO:0045944; GO:0046332; GO:0048148; GO:0048511; GO:0048525; GO:0060090; GO:0060325; GO:0060355; GO:0060999; GO:0061629; GO:0061733; GO:0070555; GO:0090575; GO:0097718; GO:0098586; GO:0140297; GO:1900087; GO:1901224; GO:1990258 44515 XM_029344986.2 451 106 174 207 129 Q86WC4 3.43e-25 Osteopetrosis-associated transmembrane protein 1 (Chloride channel 7 beta subunit) Homo sapiens (Human) osteoclast differentiation [GO:0030316]; transepithelial chloride transport [GO:0030321] GO:0005765; GO:0005829; GO:0030316; GO:0030321; GO:0034707 44516 XM_044327992.1 1535 999 706 1816 1243 P23098 0 Dynein beta chain, ciliary Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla) cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] GO:0005524; GO:0005737; GO:0005874; GO:0007018; GO:0008569; GO:0030030; GO:0030286; GO:0045505; GO:0051959; GO:0097729 44517 XM_044322162.1 857 1083 577 790 391 O22943 5.02e-90 Probable glycosyltransferase STELLO1 (EC 2.4.-.-) Arabidopsis thaliana (Mouse-ear cress) plant-type cell wall cellulose biosynthetic process [GO:0052324]; regulation of plant-type cell wall cellulose biosynthetic process [GO:2001009] GO:0000139; GO:0005768; GO:0005794; GO:0005802; GO:0016757; GO:0042802; GO:0052324; GO:2001009 44518 XR_006394228.1 60 25 0 0 60 NA NA NA NA NA NA 44519 XR_003825441.2 3 0 4 6 0 NA NA NA NA NA NA 44520 XM_029333771.2 633 441 522 554 585 Q54BM3 7.24e-67 Mitochondrial substrate carrier family protein G (Solute carrier family 25 member 20 homolog A) Dictyostelium discoideum (Social amoeba) NA GO:0005743; GO:0022857 44521 XR_003826218.2 309 84 533 406 133 NA NA NA NA NA NA 44522 XM_029329980.2 0 22 0 8 0 Q32LL6 2.84e-39 MORN repeat-containing protein 5 Bos taurus (Bovine) NA NA 44523 XM_029358045.2 1377 862 795 1274 1388 A0A0D3QS97 5.67e-25 Palmitoleoyl-protein carboxylesterase notum2 (EC 3.1.1.98) Xenopus laevis (African clawed frog) Wnt signaling pathway [GO:0016055] GO:0005576; GO:0016055; GO:0016787 44524 XM_044323375.1 0 0 4 9 61 NA NA NA NA NA NA 44525 XM_029356589.2 175 80 60 131 213 NA NA NA NA NA NA 44526 XM_029352039.2 32 0 0 0 0 Q9Y383 8.38e-74 Putative RNA-binding protein Luc7-like 2 Homo sapiens (Human) mRNA splice site selection [GO:0006376] GO:0003723; GO:0003729; GO:0005685; GO:0006376; GO:0016607; GO:0019899; GO:0071004 44527 XM_029341038.2 24 0 7 19 0 NA NA NA NA NA NA 44528 XM_029326708.2 24 19 33 22 24 NA NA NA NA NA NA 44529 XM_044322013.1 0 0 0 4 23 NA NA NA NA NA NA 44530 XM_029333639.2 268 117 96 182 253 Q61115 0 Protein patched homolog 1 (PTC) (PTC1) Mus musculus (Mouse) animal organ morphogenesis [GO:0009887]; brain development [GO:0007420]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell differentiation involved in kidney development [GO:0061005]; cell fate determination [GO:0001709]; cell proliferation involved in metanephros development [GO:0072203]; cellular response to cholesterol [GO:0071397]; commissural neuron axon guidance [GO:0071679]; dorsal/ventral neural tube patterning [GO:0021904]; dorsal/ventral pattern formation [GO:0009953]; embryonic limb morphogenesis [GO:0030326]; embryonic organ development [GO:0048568]; epidermal cell fate specification [GO:0009957]; epidermis development [GO:0008544]; epithelial cell proliferation [GO:0050673]; glucose homeostasis [GO:0042593]; heart morphogenesis [GO:0003007]; hindlimb morphogenesis [GO:0035137]; in utero embryonic development [GO:0001701]; keratinocyte proliferation [GO:0043616]; limb morphogenesis [GO:0035108]; liver regeneration [GO:0097421]; mammary gland development [GO:0030879]; mammary gland duct morphogenesis [GO:0060603]; mammary gland epithelial cell differentiation [GO:0060644]; metanephric collecting duct development [GO:0072205]; negative regulation of cell division [GO:0051782]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of stem cell proliferation [GO:2000647]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural plate axis specification [GO:0021997]; neural tube closure [GO:0001843]; neural tube formation [GO:0001841]; neural tube patterning [GO:0021532]; pattern specification process [GO:0007389]; pharyngeal system development [GO:0060037]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epidermal cell differentiation [GO:0045606]; prostate gland development [GO:0030850]; protein localization to plasma membrane [GO:0072659]; protein processing [GO:0016485]; regulation of cell population proliferation [GO:0042127]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of protein localization [GO:0032880]; response to chlorate [GO:0010157]; response to estradiol [GO:0032355]; response to mechanical stimulus [GO:0009612]; response to retinoic acid [GO:0032526]; response to xenobiotic stimulus [GO:0009410]; signal transduction [GO:0007165]; smooth muscle tissue development [GO:0048745]; somite development [GO:0061053]; spermatid development [GO:0007286]; spinal cord motor neuron differentiation [GO:0021522]; stem cell proliferation [GO:0072089] GO:0000122; GO:0001658; GO:0001701; GO:0001709; GO:0001841; GO:0001843; GO:0003007; GO:0005113; GO:0005119; GO:0005576; GO:0005634; GO:0005794; GO:0005886; GO:0005901; GO:0005929; GO:0007165; GO:0007286; GO:0007346; GO:0007389; GO:0007420; GO:0008158; GO:0008201; GO:0008270; GO:0008285; GO:0008544; GO:0009410; GO:0009612; GO:0009887; GO:0009953; GO:0009957; GO:0010157; GO:0010839; GO:0010875; GO:0014069; GO:0015485; GO:0016485; GO:0021522; GO:0021532; GO:0021904; GO:0021997; GO:0030326; GO:0030332; GO:0030496; GO:0030850; GO:0030879; GO:0032355; GO:0032526; GO:0032880; GO:0035108; GO:0035137; GO:0040008; GO:0040015; GO:0042127; GO:0042593; GO:0043231; GO:0043433; GO:0043616; GO:0044294; GO:0044295; GO:0044877; GO:0045177; GO:0045606; GO:0045668; GO:0045879; GO:0045892; GO:0045893; GO:0048471; GO:0048568; GO:0048745; GO:0050673; GO:0050680; GO:0051782; GO:0060037; GO:0060603; GO:0060644; GO:0061005; GO:0061053; GO:0071397; GO:0071679; GO:0072089; GO:0072203; GO:0072205; GO:0072659; GO:0097108; GO:0097421; GO:2000647 44531 XR_006392756.1 3 7 19 20 36 NA NA NA NA NA NA 44532 XM_029338028.2 281 104 43 39 137 NA NA NA NA NA NA 44533 XM_044307636.1 0 12 6 8 1 P79385 2.91e-21 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (SED1) (Sperm surface protein SP47) (PP47) Sus scrofa (Pig) angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; single fertilization [GO:0007338] GO:0001525; GO:0002080; GO:0005576; GO:0007155; GO:0007338 44534 XM_029329497.2 820 454 376 800 1208 P09057 3.37e-158 Ornithine decarboxylase (ODC) (EC 4.1.1.17) Rattus norvegicus (Rat) cell population proliferation [GO:0008283]; kidney development [GO:0001822]; polyamine metabolic process [GO:0006595]; positive regulation of cell population proliferation [GO:0008284]; putrescine biosynthetic process [GO:0009446]; putrescine biosynthetic process from ornithine [GO:0033387]; regulation of protein catabolic process [GO:0042176]; response to virus [GO:0009615] GO:0001822; GO:0004586; GO:0005737; GO:0005829; GO:0006595; GO:0008283; GO:0008284; GO:0009446; GO:0009615; GO:0033387; GO:0042176; GO:0042803; GO:0048471 44535 XM_044313484.1 8 0 17 0 8 NA NA NA NA NA NA 44536 XM_044314714.1 0 0 0 1677 348 NA NA NA NA NA NA 44537 XM_044325664.1 23 0 7 11 19 NA NA NA NA NA NA 44538 XM_029356561.2 6852 3804 3940 9611 10647 Q9VBW3 2.12e-77 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 44539 XM_044321305.1 0 0 54 0 0 Q13416 1.73e-112 Origin recognition complex subunit 2 Homo sapiens (Human) DNA replication initiation [GO:0006270]; negative regulation of transcription by RNA polymerase II [GO:0000122] GO:0000122; GO:0000781; GO:0000792; GO:0000808; GO:0000939; GO:0003688; GO:0005634; GO:0005654; GO:0005664; GO:0005813; GO:0006270; GO:0016020 44540 XM_044320367.1 4 54 75 70 81 NA NA NA NA NA NA 44541 XM_044327745.1 38 27 2 41 28 NA NA NA NA NA NA 44542 XM_044313564.1 19 4 2 20 18 NA NA NA NA NA NA 44543 XM_044325132.1 1148 1021 601 1066 1048 Q5JUK3 0 Potassium channel subfamily T member 1 (KCa4.1) Homo sapiens (Human) NA GO:0005228; GO:0005886; GO:0015271; GO:0016020 44544 XM_029334868.2 171 82 69 109 123 P70428 0 Exostosin-2 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Multiple exostoses protein 2 homolog) Mus musculus (Mouse) cellular polysaccharide biosynthetic process [GO:0033692]; cellular response to fibroblast growth factor stimulus [GO:0044344]; chondrocyte differentiation [GO:0002062]; endochondral bone morphogenesis [GO:0060350]; fluid transport [GO:0042044]; gene expression [GO:0010467]; glycosaminoglycan biosynthetic process [GO:0006024]; heart contraction [GO:0060047]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0015014]; heparin biosynthetic process [GO:0030210]; mesoderm formation [GO:0001707]; multicellular organismal water homeostasis [GO:0050891]; ossification [GO:0001503]; protein N-linked glycosylation [GO:0006487]; regulation of blood pressure [GO:0008217]; sodium ion homeostasis [GO:0055078]; sulfation [GO:0051923]; vasodilation [GO:0042311] GO:0000139; GO:0001503; GO:0001707; GO:0002062; GO:0005783; GO:0005789; GO:0005794; GO:0006024; GO:0006487; GO:0008217; GO:0008375; GO:0010467; GO:0015012; GO:0015014; GO:0015020; GO:0016757; GO:0030210; GO:0033692; GO:0042044; GO:0042311; GO:0042328; GO:0042803; GO:0043541; GO:0044344; GO:0046872; GO:0046982; GO:0050508; GO:0050509; GO:0050891; GO:0051923; GO:0055078; GO:0060047; GO:0060350 44545 XM_029328770.2 10 0 0 0 125 Q28615 1.35e-151 Solute carrier family 13 member 2 (Na(+)/dicarboxylate cotransporter 1) (NaDC-1) (Renal sodium/dicarboxylate cotransporter) Oryctolagus cuniculus (Rabbit) alpha-ketoglutarate transport [GO:0015742]; fumarate transport [GO:0015741]; succinate transmembrane transport [GO:0071422] GO:0015138; GO:0015139; GO:0015141; GO:0015741; GO:0015742; GO:0016324; GO:0017153; GO:0071422 44546 XM_044320612.1 0 0 0 0 6 NA NA NA NA NA NA 44547 XM_029349273.2 157 441 0 63 12 Q9UHJ3 1.18e-82 Scm-like with four MBT domains protein 1 (hSFMBT) (Renal ubiquitous protein 1) Homo sapiens (Human) cell differentiation [GO:0030154]; chromatin organization [GO:0006325]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of muscle organ development [GO:0048635]; spermatogenesis [GO:0007283] GO:0003682; GO:0003714; GO:0005634; GO:0005654; GO:0006325; GO:0007283; GO:0030154; GO:0042393; GO:0045892; GO:0048635 44548 XM_044313533.1 60 40 26 33 50 Q9BRB3 7.46e-45 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q (N-acetylglucosamyl transferase component GPI1) (Phosphatidylinositol-glycan biosynthesis class Q protein) (PIG-Q) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; GPI anchor biosynthetic process [GO:0006506] GO:0000506; GO:0005783; GO:0005789; GO:0005975; GO:0006506 44549 XM_029356270.2 7 9 2 0 69 NA NA NA NA NA NA 44550 XM_044307179.1 0 0 3 0 9 NA NA NA NA NA NA 44551 XM_044313476.1 12 0 0 0 0 NA NA NA NA NA NA 44552 XM_029337782.2 411 245 252 313 791 Q6P9I7 0 Structural maintenance of chromosomes protein 6 (SMC protein 6) (SMC-6) (xSMC6) Xenopus laevis (African clawed frog) cellular senescence [GO:0090398]; DNA repair [GO:0006281]; telomere maintenance via recombination [GO:0000722] GO:0000722; GO:0000781; GO:0005524; GO:0006281; GO:0016605; GO:0030915; GO:0090398 44553 XM_044316922.1 1180 942 635 1279 942 Q6PBA8 1.77e-82 Meiosis-specific nuclear structural protein 1 Danio rerio (Zebrafish) (Brachydanio rerio) cilium organization [GO:0044782]; meiotic cell cycle [GO:0051321] GO:0005634; GO:0005879; GO:0005930; GO:0031514; GO:0044782; GO:0051321 44554 XM_044308638.1 2052 581 897 2081 1597 NA NA NA NA NA NA 44555 XR_006393888.1 9 0 25 2 37 NA NA NA NA NA NA 44556 XM_044328660.1 59 235 114 478 286 Q49SH1 2.56e-87 Sodium/potassium/calcium exchanger 5 (Na(+)/K(+)/Ca(2+)-exchange protein 5) (Protein golden) (Solute carrier family 24 member 5) Danio rerio (Zebrafish) (Brachydanio rerio) calcium ion transport [GO:0006816]; potassium ion transport [GO:0006813]; response to stimulus [GO:0050896]; sodium ion transport [GO:0006814] GO:0005794; GO:0006813; GO:0006814; GO:0006816; GO:0015293; GO:0015297; GO:0016020; GO:0042470; GO:0050896 44557 XM_044309165.1 449 1436 617 43 374 NA NA NA NA NA NA 44558 XM_029333345.2 35 5 12 28 52 NA NA NA NA NA NA 44559 XM_044311728.1 89 60 30 81 102 B8VIU6 2.39e-41 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 44560 XM_044329232.1 0 8 2 6 6 Q99315 6.39e-76 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 44561 XM_029346198.2 0 126 0 48 83 Q9I8C7 3.47e-90 Neuronal acetylcholine receptor subunit alpha-10 (Alpha 10 nAChR) (Nicotinic acetylcholine receptor subunit alpha-10) (NACHR alpha-10) Gallus gallus (Chicken) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; response to auditory stimulus [GO:0010996]; signal transduction [GO:0007165] GO:0004888; GO:0005231; GO:0005262; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0010996; GO:0022848; GO:0030594; GO:0034220; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051899; GO:1904315 44562 XM_029330091.2 214 110 63 138 176 A7RX26 0 Probable imidazolonepropionase (EC 3.5.2.7) (Amidohydrolase domain-containing protein 1 homolog) Nematostella vectensis (Starlet sea anemone) histidine catabolic process [GO:0006548]; histidine catabolic process to glutamate and formamide [GO:0019556]; histidine catabolic process to glutamate and formate [GO:0019557] GO:0005737; GO:0006548; GO:0019556; GO:0019557; GO:0046872; GO:0050480 44563 XR_006392984.1 41 2 25 5 151 NA NA NA NA NA NA 44564 XM_029330631.2 2487 1892 1635 2923 2461 Q8NDA8 0 Maestro heat-like repeat-containing protein family member 1 (HEAT repeat-containing protein 7A) Homo sapiens (Human) NA GO:0005737 44565 XM_044326033.1 395 286 0 540 95 E1BKH1 0 EF-hand domain-containing protein 1 (Myoclonin-1) Bos taurus (Bovine) cerebral cortex cell migration [GO:0021795]; cilium-dependent cell motility [GO:0060285]; mitotic cytokinesis [GO:0000281]; mitotic spindle organization [GO:0007052]; regulation of cell division [GO:0051302] GO:0000281; GO:0000922; GO:0005509; GO:0005813; GO:0005879; GO:0005930; GO:0007052; GO:0021795; GO:0043014; GO:0051302; GO:0060285; GO:0072686 44566 XM_044323037.1 167 58 317 0 562 Q6P1L5 6.13e-25 Protein FAM117B (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 13 protein) Homo sapiens (Human) NA NA 44567 XM_044309397.1 0 43 1 2 38 NA NA NA NA NA NA 44568 XM_029338653.2 3985 372 1083 661 3249 P47937 2.49e-29 Neuromedin-K receptor (NKR) (NK-3 receptor) (NK-3R) (Neurokinin B receptor) (Tachykinin receptor 3) Mus musculus (Mouse) aging [GO:0007568]; hyperosmotic salinity response [GO:0042538]; positive regulation of blood pressure [GO:0045777]; positive regulation of flagellated sperm motility [GO:1902093]; positive regulation of heart rate [GO:0010460]; positive regulation of uterine smooth muscle contraction [GO:0070474]; regulation of dopamine metabolic process [GO:0042053]; regulation of feeding behavior [GO:0060259]; response to cocaine [GO:0042220]; response to estradiol [GO:0032355]; response to morphine [GO:0043278] GO:0004995; GO:0005634; GO:0005737; GO:0005886; GO:0007568; GO:0010460; GO:0016020; GO:0032355; GO:0032590; GO:0032809; GO:0042053; GO:0042220; GO:0042538; GO:0043278; GO:0045777; GO:0060259; GO:0070474; GO:0097225; GO:1902093 44569 XM_044323725.1 0 6 28 7 9 NA NA NA NA NA NA 44570 XM_029356454.2 0 109 508 0 1 Q60544 0 Transcription initiation factor TFIID subunit 1 (EC 2.3.1.48) (EC 2.7.11.1) (Cell cycle gene 1 protein) (TBP-associated factor 250 kDa) (p250) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250) Mesocricetus auratus (Golden hamster) cell cycle [GO:0007049]; phosphorylation [GO:0016310]; positive regulation of transcription by RNA polymerase II [GO:0045944]; transcription initiation at RNA polymerase II promoter [GO:0006367] GO:0001091; GO:0003677; GO:0004402; GO:0004674; GO:0005524; GO:0005669; GO:0006367; GO:0007049; GO:0016251; GO:0016310; GO:0017025; GO:0045944; GO:0071339; GO:0106310 44571 XR_006392886.1 41 2 25 5 151 NA NA NA NA NA NA 44572 XM_044307243.1 13 7 4 8 6 NA NA NA NA NA NA 44573 XR_006395282.1 25 2 56 0 16 NA NA NA NA NA NA 44574 XM_029332056.2 388 325 234 443 286 P52624 2.89e-89 Uridine phosphorylase 1 (UPase 1) (UrdPase 1) (EC 2.4.2.3) Mus musculus (Mouse) cellular response to glucose starvation [GO:0042149]; CMP catabolic process [GO:0006248]; dCMP catabolic process [GO:0006249]; dTMP catabolic process [GO:0046074]; dUMP catabolic process [GO:0046079]; pyrimidine nucleotide metabolic process [GO:0006220]; UMP catabolic process [GO:0046050]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]; uridine metabolic process [GO:0046108] GO:0004850; GO:0005654; GO:0005829; GO:0006218; GO:0006220; GO:0006248; GO:0006249; GO:0009032; GO:0042149; GO:0042802; GO:0044206; GO:0046050; GO:0046074; GO:0046079; GO:0046108; GO:0047847 44575 XM_029337540.2 421 316 277 268 282 Q8VCK5 2.05e-160 Kelch-like protein 20 (Kelch-like ECT2-interacting protein) Mus musculus (Mouse) Golgi to endosome transport [GO:0006895]; negative regulation of apoptotic process [GO:0043066]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K33-linked ubiquitination [GO:1990390]; protein transport [GO:0015031]; protein ubiquitination [GO:0016567] GO:0003779; GO:0004842; GO:0005737; GO:0005794; GO:0005802; GO:0005829; GO:0006895; GO:0015031; GO:0016567; GO:0016605; GO:0019964; GO:0030424; GO:0030425; GO:0031463; GO:0043066; GO:0043161; GO:0048471; GO:1990390 44576 XM_044317197.1 0 0 7 0 0 A8MZ26 7.39e-50 EF-hand calcium-binding domain-containing protein 9 Homo sapiens (Human) flagellated sperm motility [GO:0030317]; sperm capacitation [GO:0048240]; spermatogenesis [GO:0007283] GO:0005509; GO:0005737; GO:0007283; GO:0030317; GO:0036128; GO:0048240; GO:0061891; GO:0097228 44577 XM_044322000.1 61 0 0 0 0 A2VDD2 1.99e-22 Dynein light chain Tctex-type 5-B (Tctex1 domain-containing protein 1-B) Xenopus laevis (African clawed frog) NA NA 44578 XM_044312273.1 0 0 26 34 7 NA NA NA NA NA NA 44579 XM_029356222.2 74 68 43 88 52 O94993 1.23e-22 Transcription factor SOX-30 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proacrosomal vesicle fusion [GO:0120211]; regulation of transcription by RNA polymerase II [GO:0006357]; response to corticosteroid [GO:0031960]; spermatid development [GO:0007286] GO:0000122; GO:0000785; GO:0000978; GO:0000981; GO:0001227; GO:0001228; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006357; GO:0007286; GO:0008013; GO:0010369; GO:0030178; GO:0031960; GO:0043231; GO:0045944; GO:0120211; GO:1990837 44580 XM_029344215.2 656 738 191 278 169 Q6DH69 1.53e-136 Fatty-acid amide hydrolase 2-A (EC 3.5.1.99) Danio rerio (Zebrafish) (Brachydanio rerio) lipid catabolic process [GO:0016042] GO:0016020; GO:0016042; GO:0017064 44581 XM_044316752.1 0 1 4 1 14 NA NA NA NA NA NA 44582 XM_044324065.1 0 10 0 0 6 Q0V9T8 6.08e-99 Basic immunoglobulin-like variable motif-containing protein Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005634; GO:0005737 44583 XM_044307502.1 0 1 0 6 0 NA NA NA NA NA NA 44584 XR_006397039.1 46 8 9 3 129 NA NA NA NA NA NA 44585 XM_044324043.1 0 0 0 7 33 D3ZZL9 7.99e-90 GRIP and coiled-coil domain-containing protein 2 (185 kDa Golgi coiled-coil protein) Rattus norvegicus (Rat) Golgi ribbon formation [GO:0090161]; late endosome to Golgi transport [GO:0034499]; microtubule anchoring [GO:0034453]; microtubule organizing center organization [GO:0031023]; protein localization to Golgi apparatus [GO:0034067]; protein targeting to lysosome [GO:0006622]; recycling endosome to Golgi transport [GO:0071955]; regulation of protein exit from endoplasmic reticulum [GO:0070861]; retrograde transport, endosome to Golgi [GO:0042147] GO:0005794; GO:0005802; GO:0005829; GO:0006622; GO:0016020; GO:0031023; GO:0034067; GO:0034453; GO:0034499; GO:0042147; GO:0042802; GO:0070861; GO:0071955; GO:0090161 44586 XM_029357562.2 4 22 7 47 55 NA NA NA NA NA NA 44587 XM_029350720.2 20 16 0 0 0 NA NA NA NA NA NA 44588 XR_006394153.1 13 6 20 0 83 NA NA NA NA NA NA 44589 XM_044326310.1 81 48 75 79 137 Q9D2Z4 1.72e-50 Sentrin-specific protease 8 (EC 3.4.22.-) (Deneddylase-1) (NEDD8-specific protease 1) (Sentrin/SUMO-specific protease SENP8) Mus musculus (Mouse) protein desumoylation [GO:0016926] GO:0005634; GO:0008234; GO:0016926; GO:0016929; GO:0019784 44590 XM_029330402.2 1678 1028 984 1797 1744 B4F6W9 0 E3 ubiquitin-protein ligase TRIP12 (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase TRIP12) (Thyroid receptor-interacting protein 12) (TR-interacting protein 12) (TRIP-12) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) DNA repair [GO:0006281]; DNA repair-dependent chromatin remodeling [GO:0140861]; negative regulation of double-strand break repair [GO:2000780]; negative regulation of histone H2A K63-linked ubiquitination [GO:1901315]; protein polyubiquitination [GO:0000209]; regulation of embryonic development [GO:0045995]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000209; GO:0005654; GO:0006281; GO:0006511; GO:0008270; GO:0045995; GO:0061630; GO:0140861; GO:1901315; GO:2000780 44591 XR_003822716.2 63 21 0 60 123 NA NA NA NA NA NA 44592 XR_003825058.2 16 0 22 61 52 NA NA NA NA NA NA 44593 XM_044313864.1 1656 398 107 172 34 NA NA NA NA NA NA 44594 XM_029332031.2 1321 2165 1123 1426 2033 P05205 1.01e-30 Heterochromatin protein 1 (HP1) (Non-histone chromosomal protein C1A9 antigen) Drosophila melanogaster (Fruit fly) chromatin organization [GO:0006325]; chromosome organization [GO:0051276]; heterochromatin formation [GO:0031507]; mitotic cell cycle [GO:0000278]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pericentric heterochromatin formation [GO:0031508]; positive regulation of DNA methylation-dependent heterochromatin formation [GO:0090309]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of FACT complex assembly [GO:1905646]; positive regulation of transcription from RNA polymerase II promoter in response to heat stress [GO:0061408]; protein localization to euchromatin [GO:1905632]; regulation of DNA-templated transcription [GO:0006355]; regulation of protein localization to chromatin [GO:1905634]; telomere maintenance [GO:0000723] GO:0000122; GO:0000182; GO:0000278; GO:0000723; GO:0000775; GO:0000779; GO:0000781; GO:0000791; GO:0000792; GO:0000793; GO:0003682; GO:0003696; GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0005694; GO:0005700; GO:0005701; GO:0005703; GO:0005721; GO:0006325; GO:0006355; GO:0010369; GO:0010629; GO:0030544; GO:0030674; GO:0031507; GO:0031508; GO:0035064; GO:0042393; GO:0044877; GO:0045892; GO:0045893; GO:0051276; GO:0061408; GO:0070063; GO:0090309; GO:0099122; GO:1905632; GO:1905634; GO:1905646 44595 XM_029348550.2 71 10 50 0 52 B1H283 1.1e-58 Lymphocyte expansion molecule Rattus norvegicus (Rat) positive regulation of cell population proliferation [GO:0008284]; positive regulation of oxidative phosphorylation [GO:1903862] GO:0005739; GO:0008284; GO:0097177; GO:1903862 44596 XM_029358061.2 48 17 21 69 54 NA NA NA NA NA NA 44597 XM_044320991.1 0 0 172 16 102 O15050 0 TPR and ankyrin repeat-containing protein 1 (Lupus brain antigen 1 homolog) Homo sapiens (Human) NA NA 44598 XR_006395044.1 52 40 118 99 107 Q6IVV8 5.29e-33 Polycystin-2 (Curly up) (Cup) (Polycystic kidney disease 2 protein homolog) (Transient receptor potential cation channel subfamily P member 2) Danio rerio (Zebrafish) (Brachydanio rerio) atrioventricular valve development [GO:0003171]; calcium ion transmembrane transport [GO:0070588]; cell-cell signaling by wnt [GO:0198738]; cellular response to calcium ion [GO:0071277]; cellular response to oscillatory fluid shear stress [GO:0097704]; cilium assembly [GO:0060271]; detection of mechanical stimulus [GO:0050982]; determination of heart left/right asymmetry [GO:0061371]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic heart tube morphogenesis [GO:0003143]; heart development [GO:0007507]; heart jogging [GO:0003146]; heart looping [GO:0001947]; hematopoietic progenitor cell differentiation [GO:0002244]; inorganic cation transmembrane transport [GO:0098662]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; lymphangiogenesis [GO:0001946]; Notch signaling pathway [GO:0007219]; positive regulation of sequestering of calcium ion [GO:0051284]; potassium ion transmembrane transport [GO:0071805]; pronephros development [GO:0048793]; pronephros morphogenesis [GO:0072114]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; proximal convoluted tubule development [GO:0072019]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of collagen biosynthetic process [GO:0032965]; regulation of ion transmembrane transport [GO:0034765]; release of sequestered calcium ion into cytosol [GO:0051209]; ventriculo bulbo valve development [GO:0003173]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001946; GO:0001947; GO:0002244; GO:0003143; GO:0003146; GO:0003171; GO:0003173; GO:0005102; GO:0005245; GO:0005248; GO:0005261; GO:0005262; GO:0005267; GO:0005509; GO:0005783; GO:0005856; GO:0005886; GO:0005929; GO:0007219; GO:0007368; GO:0007507; GO:0009953; GO:0010882; GO:0015271; GO:0016020; GO:0016055; GO:0016323; GO:0016324; GO:0016328; GO:0030017; GO:0030659; GO:0032965; GO:0033017; GO:0034703; GO:0034765; GO:0042383; GO:0048793; GO:0050982; GO:0051209; GO:0051262; GO:0051284; GO:0051290; GO:0051371; GO:0060271; GO:0060972; GO:0061371; GO:0065003; GO:0070121; GO:0070588; GO:0071277; GO:0071805; GO:0072019; GO:0072114; GO:0097704; GO:0098662; GO:0198738 44599 XR_006395044.1 52 40 118 99 107 Q6IVV8 5.29e-33 Polycystin-2 (Curly up) (Cup) (Polycystic kidney disease 2 protein homolog) (Transient receptor potential cation channel subfamily P member 2) Danio rerio (Zebrafish) (Brachydanio rerio) atrioventricular valve development [GO:0003171]; calcium ion transmembrane transport [GO:0070588]; cell-cell signaling by wnt [GO:0198738]; cellular response to calcium ion [GO:0071277]; cellular response to oscillatory fluid shear stress [GO:0097704]; cilium assembly [GO:0060271]; detection of mechanical stimulus [GO:0050982]; determination of heart left/right asymmetry [GO:0061371]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic heart tube morphogenesis [GO:0003143]; heart development [GO:0007507]; heart jogging [GO:0003146]; heart looping [GO:0001947]; hematopoietic progenitor cell differentiation [GO:0002244]; inorganic cation transmembrane transport [GO:0098662]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; lymphangiogenesis [GO:0001946]; Notch signaling pathway [GO:0007219]; positive regulation of sequestering of calcium ion [GO:0051284]; potassium ion transmembrane transport [GO:0071805]; pronephros development [GO:0048793]; pronephros morphogenesis [GO:0072114]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; proximal convoluted tubule development [GO:0072019]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of collagen biosynthetic process [GO:0032965]; regulation of ion transmembrane transport [GO:0034765]; release of sequestered calcium ion into cytosol [GO:0051209]; ventriculo bulbo valve development [GO:0003173]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001946; GO:0001947; GO:0002244; GO:0003143; GO:0003146; GO:0003171; GO:0003173; GO:0005102; GO:0005245; GO:0005248; GO:0005261; GO:0005262; GO:0005267; GO:0005509; GO:0005783; GO:0005856; GO:0005886; GO:0005929; GO:0007219; GO:0007368; GO:0007507; GO:0009953; GO:0010882; GO:0015271; GO:0016020; GO:0016055; GO:0016323; GO:0016324; GO:0016328; GO:0030017; GO:0030659; GO:0032965; GO:0033017; GO:0034703; GO:0034765; GO:0042383; GO:0048793; GO:0050982; GO:0051209; GO:0051262; GO:0051284; GO:0051290; GO:0051371; GO:0060271; GO:0060972; GO:0061371; GO:0065003; GO:0070121; GO:0070588; GO:0071277; GO:0071805; GO:0072019; GO:0072114; GO:0097704; GO:0098662; GO:0198738 44600 XR_006395044.1 52 40 118 99 107 Q6IVV8 5.29e-33 Polycystin-2 (Curly up) (Cup) (Polycystic kidney disease 2 protein homolog) (Transient receptor potential cation channel subfamily P member 2) Danio rerio (Zebrafish) (Brachydanio rerio) atrioventricular valve development [GO:0003171]; calcium ion transmembrane transport [GO:0070588]; cell-cell signaling by wnt [GO:0198738]; cellular response to calcium ion [GO:0071277]; cellular response to oscillatory fluid shear stress [GO:0097704]; cilium assembly [GO:0060271]; detection of mechanical stimulus [GO:0050982]; determination of heart left/right asymmetry [GO:0061371]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic heart tube morphogenesis [GO:0003143]; heart development [GO:0007507]; heart jogging [GO:0003146]; heart looping [GO:0001947]; hematopoietic progenitor cell differentiation [GO:0002244]; inorganic cation transmembrane transport [GO:0098662]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; lymphangiogenesis [GO:0001946]; Notch signaling pathway [GO:0007219]; positive regulation of sequestering of calcium ion [GO:0051284]; potassium ion transmembrane transport [GO:0071805]; pronephros development [GO:0048793]; pronephros morphogenesis [GO:0072114]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; proximal convoluted tubule development [GO:0072019]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of collagen biosynthetic process [GO:0032965]; regulation of ion transmembrane transport [GO:0034765]; release of sequestered calcium ion into cytosol [GO:0051209]; ventriculo bulbo valve development [GO:0003173]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001946; GO:0001947; GO:0002244; GO:0003143; GO:0003146; GO:0003171; GO:0003173; GO:0005102; GO:0005245; GO:0005248; GO:0005261; GO:0005262; GO:0005267; GO:0005509; GO:0005783; GO:0005856; GO:0005886; GO:0005929; GO:0007219; GO:0007368; GO:0007507; GO:0009953; GO:0010882; GO:0015271; GO:0016020; GO:0016055; GO:0016323; GO:0016324; GO:0016328; GO:0030017; GO:0030659; GO:0032965; GO:0033017; GO:0034703; GO:0034765; GO:0042383; GO:0048793; GO:0050982; GO:0051209; GO:0051262; GO:0051284; GO:0051290; GO:0051371; GO:0060271; GO:0060972; GO:0061371; GO:0065003; GO:0070121; GO:0070588; GO:0071277; GO:0071805; GO:0072019; GO:0072114; GO:0097704; GO:0098662; GO:0198738 44601 XM_029348427.2 1029 1380 506 824 604 NA NA NA NA NA NA 44602 XM_029338114.2 69 17 50 115 46 Q7ZXK9 0 Notchless protein homolog 1 Xenopus laevis (African clawed frog) Notch signaling pathway [GO:0007219] GO:0005730; GO:0007219 44603 XR_003826354.2 10 4 8 5 7 NA NA NA NA NA NA 44604 XM_044315752.1 12 2 2 54 49 Q7RTR2 2.34e-68 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 44605 XM_044315752.1 12 2 2 54 49 Q7RTR2 1.17e-64 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 44606 XM_044315752.1 12 2 2 54 49 Q7RTR2 7.82e-64 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 44607 XM_044315752.1 12 2 2 54 49 Q7RTR2 7.15e-58 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 44608 XM_044315752.1 12 2 2 54 49 Q7RTR2 9.08e-49 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 44609 XM_044315752.1 12 2 2 54 49 Q7RTR2 9.24e-49 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 44610 XM_044315752.1 12 2 2 54 49 Q7RTR2 2.63e-48 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 44611 XR_006398194.1 2 0 0 10 8 NA NA NA NA NA NA 44612 XR_006396559.1 48 44 28 0 13 NA NA NA NA NA NA 44613 XR_006393503.1 19 19 5 1 34 NA NA NA NA NA NA 44614 XR_003827897.2 0 0 19 0 210 NA NA NA NA NA NA 44615 XM_029340548.2 267 211 168 218 180 Q5EAB6 0 Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGnT1) (EC 2.4.1.-) Bos taurus (Bovine) O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493] GO:0000139; GO:0006493; GO:0008375; GO:0016020; GO:0016266; GO:0030145 44616 XM_044322916.1 1043 1114 100 352 4555 C6FG12 6.45e-25 Protein NLRC5 Ictalurus punctatus (Channel catfish) (Silurus punctatus) innate immune response [GO:0045087] GO:0005524; GO:0005737; GO:0045087 44617 XM_029336840.2 18 0 21 0 38 O42409 2.91e-93 Zinc finger protein Gfi-1b (Growth factor-independent protein 1B) Gallus gallus (Chicken) chromatin organization [GO:0006325]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001227; GO:0005654; GO:0006325; GO:0006357; GO:0046872 44618 XM_029336840.2 18 0 21 0 38 O42409 2.43e-21 Zinc finger protein Gfi-1b (Growth factor-independent protein 1B) Gallus gallus (Chicken) chromatin organization [GO:0006325]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001227; GO:0005654; GO:0006325; GO:0006357; GO:0046872 44619 XM_029344729.2 218 281 36 557 423 Q5R2J4 2.73e-70 Protein APCDD1 (Adenomatosis polyposis coli down-regulated 1 protein homolog) (PsAPCDD1) Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis) negative regulation of Wnt signaling pathway [GO:0030178]; Wnt signaling pathway [GO:0016055] GO:0005615; GO:0005886; GO:0016055; GO:0017147; GO:0030178 44620 XM_044320522.1 782 214 310 417 1132 P55115 1.04e-36 Zinc metalloproteinase nas-15 (EC 3.4.24.-) (Nematode astacin 15) Caenorhabditis elegans proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0006508; GO:0008270 44621 XM_029340092.2 3651 6568 2306 6082 3125 Q0GGW5 1.49e-157 Serine/threonine-protein kinase STK11 (EC 2.7.11.1) (Liver kinase B1 homolog) (LKB1) Gallus gallus (Chicken) activation of protein kinase activity [GO:0032147]; cell cycle [GO:0007049]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to starvation [GO:0009267]; establishment of cell polarity [GO:0030010]; glucose homeostasis [GO:0042593]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell growth [GO:0030308]; positive regulation of vesicle transport along microtubule [GO:1901610]; protein autophosphorylation [GO:0046777]; protein dephosphorylation [GO:0006470]; protein phosphorylation [GO:0006468]; regulation of cell growth [GO:0001558]; regulation of Wnt signaling pathway [GO:0030111]; response to ionizing radiation [GO:0010212]; response to xenobiotic stimulus [GO:0009410]; signal transduction [GO:0007165]; vasculature development [GO:0001944] GO:0000287; GO:0001558; GO:0001944; GO:0002039; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0006468; GO:0006470; GO:0006974; GO:0007049; GO:0007165; GO:0009267; GO:0009410; GO:0010212; GO:0016020; GO:0019901; GO:0030010; GO:0030111; GO:0030295; GO:0030308; GO:0032147; GO:0042593; GO:0046777; GO:0072332; GO:0090090; GO:0106310; GO:1901610 44622 XM_044313772.1 0 0 2 11 0 NA NA NA NA NA NA 44623 XM_044325320.1 8 13 0 3 7 Q2KIA4 5.81e-106 Stearoyl-CoA desaturase 5 (EC 1.14.19.1) (Acyl-CoA-desaturase 4) (Stearoyl-CoA 9-desaturase) Bos taurus (Bovine) monounsaturated fatty acid biosynthetic process [GO:1903966]; unsaturated fatty acid biosynthetic process [GO:0006636] GO:0004768; GO:0005506; GO:0005789; GO:0006636; GO:0016491; GO:1903966 44624 XR_006395725.1 18 0 0 0 3 NA NA NA NA NA NA 44625 XM_044318218.1 1341 901 992 965 638 NA NA NA NA NA NA 44626 XM_044315876.1 689 378 544 823 971 Q86U86 0 Protein polybromo-1 (hPB1) (BRG1-associated factor 180) (BAF180) (Polybromo-1D) Homo sapiens (Human) chromatin remodeling [GO:0006338]; mitotic cell cycle [GO:0000278]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of cell differentiation [GO:0045597]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of T cell differentiation [GO:0045582]; regulation of G0 to G1 transition [GO:0070316]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of nucleotide-excision repair [GO:2000819]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000228; GO:0000278; GO:0000776; GO:0000785; GO:0003677; GO:0003682; GO:0005634; GO:0005654; GO:0006338; GO:0006357; GO:0008285; GO:0016363; GO:0016514; GO:0016586; GO:0030071; GO:0045582; GO:0045597; GO:0045663; GO:0070316; GO:2000045; GO:2000781; GO:2000819 44627 XM_044315876.1 689 378 544 823 971 Q86U86 1.19e-54 Protein polybromo-1 (hPB1) (BRG1-associated factor 180) (BAF180) (Polybromo-1D) Homo sapiens (Human) chromatin remodeling [GO:0006338]; mitotic cell cycle [GO:0000278]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of cell differentiation [GO:0045597]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of T cell differentiation [GO:0045582]; regulation of G0 to G1 transition [GO:0070316]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of nucleotide-excision repair [GO:2000819]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000228; GO:0000278; GO:0000776; GO:0000785; GO:0003677; GO:0003682; GO:0005634; GO:0005654; GO:0006338; GO:0006357; GO:0008285; GO:0016363; GO:0016514; GO:0016586; GO:0030071; GO:0045582; GO:0045597; GO:0045663; GO:0070316; GO:2000045; GO:2000781; GO:2000819 44628 XM_044315876.1 689 378 544 823 971 Q86U86 1.64e-35 Protein polybromo-1 (hPB1) (BRG1-associated factor 180) (BAF180) (Polybromo-1D) Homo sapiens (Human) chromatin remodeling [GO:0006338]; mitotic cell cycle [GO:0000278]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of cell differentiation [GO:0045597]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of T cell differentiation [GO:0045582]; regulation of G0 to G1 transition [GO:0070316]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of nucleotide-excision repair [GO:2000819]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000228; GO:0000278; GO:0000776; GO:0000785; GO:0003677; GO:0003682; GO:0005634; GO:0005654; GO:0006338; GO:0006357; GO:0008285; GO:0016363; GO:0016514; GO:0016586; GO:0030071; GO:0045582; GO:0045597; GO:0045663; GO:0070316; GO:2000045; GO:2000781; GO:2000819 44629 XM_044315876.1 689 378 544 823 971 Q86U86 1.35e-29 Protein polybromo-1 (hPB1) (BRG1-associated factor 180) (BAF180) (Polybromo-1D) Homo sapiens (Human) chromatin remodeling [GO:0006338]; mitotic cell cycle [GO:0000278]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of cell differentiation [GO:0045597]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of T cell differentiation [GO:0045582]; regulation of G0 to G1 transition [GO:0070316]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of nucleotide-excision repair [GO:2000819]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000228; GO:0000278; GO:0000776; GO:0000785; GO:0003677; GO:0003682; GO:0005634; GO:0005654; GO:0006338; GO:0006357; GO:0008285; GO:0016363; GO:0016514; GO:0016586; GO:0030071; GO:0045582; GO:0045597; GO:0045663; GO:0070316; GO:2000045; GO:2000781; GO:2000819 44630 XM_044315876.1 689 378 544 823 971 Q86U86 1.11e-25 Protein polybromo-1 (hPB1) (BRG1-associated factor 180) (BAF180) (Polybromo-1D) Homo sapiens (Human) chromatin remodeling [GO:0006338]; mitotic cell cycle [GO:0000278]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of cell differentiation [GO:0045597]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of T cell differentiation [GO:0045582]; regulation of G0 to G1 transition [GO:0070316]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of nucleotide-excision repair [GO:2000819]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000228; GO:0000278; GO:0000776; GO:0000785; GO:0003677; GO:0003682; GO:0005634; GO:0005654; GO:0006338; GO:0006357; GO:0008285; GO:0016363; GO:0016514; GO:0016586; GO:0030071; GO:0045582; GO:0045597; GO:0045663; GO:0070316; GO:2000045; GO:2000781; GO:2000819 44631 XM_044310729.1 21 8 60 14 56 NA NA NA NA NA NA 44632 XM_029336328.2 1076 706 615 993 1677 B0XK69 1.75e-41 Succinate dehydrogenase assembly factor 2, mitochondrial (SDH assembly factor 2) (SDHAF2) Culex quinquefasciatus (Southern house mosquito) (Culex pungens) mitochondrial electron transport, succinate to ubiquinone [GO:0006121]; protein-FAD linkage [GO:0018293] GO:0005739; GO:0005759; GO:0006121; GO:0018293 44633 XR_006394588.1 20 58 7 34 23 NA NA NA NA NA NA 44634 XM_029356847.2 13806 6884 5618 14490 10345 NA NA NA NA NA NA 44635 XM_029337959.2 0 9 0 31 0 Q29611 2.13e-117 Battenin (Protein CLN3) Canis lupus familiaris (Dog) (Canis familiaris) amyloid precursor protein catabolic process [GO:0042987]; autophagosome-lysosome fusion [GO:0061909]; cellular water homeostasis [GO:0009992]; glycerophospholipid biosynthetic process [GO:0046474]; glycolipid transport [GO:0046836]; Golgi to lysosome transport [GO:0090160]; L-arginine transmembrane transport [GO:1903826]; learning or memory [GO:0007611]; lysosomal lumen acidification [GO:0007042]; lysosomal lumen pH elevation [GO:0035752]; lysosomal protein catabolic process [GO:1905146]; negative regulation of apoptotic process [GO:0043066]; phagosome-lysosome docking [GO:0090384]; phagosome-lysosome fusion [GO:0090385]; plasma membrane raft organization [GO:0044857]; positive regulation of caveolin-mediated endocytosis [GO:2001288]; positive regulation of Golgi to plasma membrane protein transport [GO:0042998]; positive regulation of pinocytosis [GO:0048549]; receptor-mediated endocytosis [GO:0006898]; regulation of arginine biosynthetic process [GO:1900079]; regulation of autophagosome maturation [GO:1901096]; regulation of cellular response to osmotic stress [GO:0106049]; regulation of cytoskeleton organization [GO:0051493]; regulation of fibroblast migration [GO:0010762]; regulation of modification of synaptic structure [GO:1905244]; regulation of phagosome maturation [GO:1905162]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of protein processing [GO:0070613]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic transmission, GABAergic [GO:0032228]; regulation of synaptic transmission, glutamatergic [GO:0051966]; renal potassium excretion [GO:0036359]; vesicle transport along microtubule [GO:0047496] GO:0000139; GO:0005634; GO:0005737; GO:0005764; GO:0005765; GO:0005769; GO:0005770; GO:0005783; GO:0005789; GO:0005794; GO:0005795; GO:0005802; GO:0005829; GO:0005886; GO:0005901; GO:0006898; GO:0007042; GO:0007611; GO:0008021; GO:0009992; GO:0010762; GO:0016020; GO:0031901; GO:0032228; GO:0035752; GO:0036359; GO:0042987; GO:0042998; GO:0043005; GO:0043066; GO:0044754; GO:0044857; GO:0045121; GO:0046474; GO:0046836; GO:0047496; GO:0048172; GO:0048549; GO:0051493; GO:0051861; GO:0051966; GO:0055037; GO:0061909; GO:0070613; GO:0090160; GO:0090384; GO:0090385; GO:0106049; GO:0120146; GO:1900079; GO:1901096; GO:1903076; GO:1903826; GO:1905146; GO:1905162; GO:1905244; GO:2001288 44636 XM_029358386.2 57 78 36 75 59 NA NA NA NA NA NA 44637 XM_029352524.2 617 233 110 510 227 Q9P2K3 1.21e-111 REST corepressor 3 Homo sapiens (Human) histone deacetylation [GO:0016575]; negative regulation of DNA-templated transcription [GO:0045892]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000118; GO:0003714; GO:0005654; GO:0005667; GO:0005829; GO:0006357; GO:0016575; GO:0045892 44638 XM_029356013.2 0 0 47 0 0 Q9JHE4 9.36e-55 Galactosylceramide sulfotransferase (GalCer sulfotransferase) (EC 2.8.2.11) (3'-phosphoadenosine-5'-phosphosulfate:GalCer sulfotransferase) (3'-phosphoadenylylsulfate:galactosylceramide 3'-sulfotransferase) (Cerebroside sulfotransferase) Mus musculus (Mouse) galactosylceramide biosynthetic process [GO:0006682]; galactosylceramide metabolic process [GO:0006681]; glycerolipid metabolic process [GO:0046486]; glycolipid biosynthetic process [GO:0009247]; myelination [GO:0042552]; spermatogenesis [GO:0007283]; sphingolipid metabolic process [GO:0006665] GO:0000139; GO:0001733; GO:0006665; GO:0006681; GO:0006682; GO:0007283; GO:0008146; GO:0009247; GO:0016020; GO:0042552; GO:0046486; GO:0050694 44639 XM_044315778.1 29 9 64 8 10 NA NA NA NA NA NA 44640 XM_029357657.2 150 111 119 155 115 NA NA NA NA NA NA 44641 XM_029330565.2 0 0 0 0 61 Q9Y5X5 7.86e-31 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (G-protein coupled receptor HLWAR77) (Neuropeptide G-protein coupled receptor) Homo sapiens (Human) detection of abiotic stimulus [GO:0009582]; G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0009582; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 44642 XM_044318136.1 606 548 154 431 221 P58197 1.73e-78 Transcription factor AP-2-alpha (AP2-alpha) (AP-2 transcription factor) (Activating enhancer-binding protein 2-alpha) (Activator protein 2) (AP-2) Rattus norvegicus (Rat) anatomical structure development [GO:0048856]; anterior neuropore closure [GO:0021506]; basement membrane organization [GO:0071711]; bone morphogenesis [GO:0060349]; cell population proliferation [GO:0008283]; cellular response to iron ion [GO:0071281]; cornea development in camera-type eye [GO:0061303]; embryonic body morphogenesis [GO:0010172]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic forelimb morphogenesis [GO:0035115]; embryonic pattern specification [GO:0009880]; epidermal growth factor receptor signaling pathway [GO:0007173]; epidermis morphogenesis [GO:0048730]; eyelid development in camera-type eye [GO:0061029]; face morphogenesis [GO:0060325]; fibroblast migration [GO:0010761]; forebrain neuron development [GO:0021884]; forelimb morphogenesis [GO:0035136]; inner ear morphogenesis [GO:0042472]; keratinocyte development [GO:0003334]; kidney development [GO:0001822]; lens induction in camera-type eye [GO:0060235]; lens morphogenesis in camera-type eye [GO:0002089]; metanephric nephron development [GO:0072210]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of transcription by competitive promoter binding [GO:0010944]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; neural crest cell development [GO:0014032]; neural tube closure [GO:0001843]; neuron apoptotic process [GO:0051402]; oculomotor nerve formation [GO:0021623]; optic cup structural organization [GO:0003409]; optic vesicle morphogenesis [GO:0003404]; outflow tract morphogenesis [GO:0003151]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of tooth mineralization [GO:0070172]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; regulation of DNA-templated transcription [GO:0006355]; regulation of neuron differentiation [GO:0045664]; regulation of transcription by RNA polymerase II [GO:0006357]; response to lipopolysaccharide [GO:0032496]; response to water deprivation [GO:0009414]; retina layer formation [GO:0010842]; roof of mouth development [GO:0060021]; Schwann cell development [GO:0014044]; sensory organ development [GO:0007423]; sensory perception of sound [GO:0007605]; skeletal system morphogenesis [GO:0048705]; skin development [GO:0043588]; sympathetic nervous system development [GO:0048485]; transcription by RNA polymerase II [GO:0006366]; trigeminal nerve development [GO:0021559] GO:0000122; GO:0000976; GO:0000977; GO:0000978; GO:0000981; GO:0000987; GO:0001227; GO:0001228; GO:0001822; GO:0001843; GO:0002089; GO:0003151; GO:0003334; GO:0003404; GO:0003409; GO:0003677; GO:0003682; GO:0003700; GO:0003713; GO:0003714; GO:0005634; GO:0005905; GO:0006355; GO:0006357; GO:0006366; GO:0007173; GO:0007399; GO:0007423; GO:0007605; GO:0008283; GO:0008285; GO:0009414; GO:0009880; GO:0010172; GO:0010628; GO:0010761; GO:0010763; GO:0010842; GO:0010944; GO:0014032; GO:0014044; GO:0021506; GO:0021559; GO:0021623; GO:0021884; GO:0030335; GO:0030501; GO:0032496; GO:0035115; GO:0035136; GO:0042059; GO:0042127; GO:0042472; GO:0042802; GO:0043066; GO:0043524; GO:0043525; GO:0043565; GO:0043588; GO:0045595; GO:0045664; GO:0045892; GO:0045893; GO:0045944; GO:0048485; GO:0048596; GO:0048701; GO:0048705; GO:0048730; GO:0048856; GO:0051402; GO:0060021; GO:0060235; GO:0060325; GO:0060349; GO:0061029; GO:0061303; GO:0070172; GO:0071281; GO:0071711; GO:0072210; GO:0140536; GO:1990837; GO:2000378 44643 XM_029336775.2 0 4 20 18 17 O42409 9.22e-77 Zinc finger protein Gfi-1b (Growth factor-independent protein 1B) Gallus gallus (Chicken) chromatin organization [GO:0006325]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001227; GO:0005654; GO:0006325; GO:0006357; GO:0046872 44644 XR_003825056.2 380 428 340 325 297 NA NA NA NA NA NA 44645 XM_044322979.1 37 697 59 804 86 NA NA NA NA NA NA 44646 XM_029356034.2 1849 653 650 1180 769 Q08CX1 1.74e-66 Ras and EF-hand domain-containing protein Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0003924; GO:0005509; GO:0005525; GO:0048471 44647 XM_029356034.2 1849 653 650 1180 769 Q08CX1 8.36e-29 Ras and EF-hand domain-containing protein Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0003924; GO:0005509; GO:0005525; GO:0048471 44648 XR_006394547.1 4 108 18 90 3 NA NA NA NA NA NA 44649 XM_044314418.1 1 12 32 4 4 NA NA NA NA NA NA 44650 XM_029327756.2 48 276 137 395 364 NA NA NA NA NA NA 44651 XM_029357626.2 24 15 16 9 31 Q6ZUK4 4.9e-28 Transmembrane protein 26 Homo sapiens (Human) NA GO:0016020 44652 XM_029351306.2 609 514 610 629 695 A3KG59 1.27e-108 Xaa-Arg dipeptidase (EC 3.4.13.4) Mus musculus (Mouse) proteolysis [GO:0006508]; regulation of protein metabolic process [GO:0051246] GO:0004180; GO:0005654; GO:0006508; GO:0016805; GO:0042802; GO:0051246 44653 XM_044317363.1 0 2 3 12 0 NA NA NA NA NA NA 44654 XM_044320591.1 455 587 386 1420 1078 NA NA NA NA NA NA 44655 XM_029342856.2 1857 1694 859 1446 1233 O15111 8.8e-153 Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase alpha) (IKK-A) (IKK-alpha) (IkBKA) (IkappaB kinase) (EC 2.7.11.10) (Conserved helix-loop-helix ubiquitous kinase) (I-kappa-B kinase 1) (IKK1) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA) (Transcription factor 16) (TCF-16) Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to virus [GO:0098586]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; I-kappaB phosphorylation [GO:0007252]; immune response [GO:0006955]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; NIK/NF-kappaB signaling [GO:0038061]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein phosphorylation [GO:0006468]; response to virus [GO:0009615]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0004672; GO:0004674; GO:0005524; GO:0005654; GO:0005737; GO:0005829; GO:0006468; GO:0006954; GO:0006955; GO:0007249; GO:0007252; GO:0008384; GO:0008385; GO:0009615; GO:0009653; GO:0009898; GO:0018105; GO:0032088; GO:0032727; GO:0033209; GO:0034614; GO:0035631; GO:0038061; GO:0042803; GO:0043123; GO:0045087; GO:0045893; GO:0045944; GO:0046982; GO:0051092; GO:0071276; GO:0071356; GO:0097110; GO:0098586; GO:1990459 44656 XM_044323940.1 0 0 11 0 0 NA NA NA NA NA NA 44657 XM_044309948.1 96 0 0 42 37 P18433 3.66e-133 Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (EC 3.1.3.48) Homo sapiens (Human) insulin receptor signaling pathway [GO:0008286]; integrin-mediated signaling pathway [GO:0007229]; modulation of chemical synaptic transmission [GO:0050804]; protein dephosphorylation [GO:0006470]; protein phosphorylation [GO:0006468]; regulation of focal adhesion assembly [GO:0051893] GO:0004725; GO:0005001; GO:0005886; GO:0005925; GO:0006468; GO:0006470; GO:0007229; GO:0008286; GO:0016020; GO:0043235; GO:0050804; GO:0051893; GO:0070062; GO:0097060; GO:0098685 44658 XM_044327052.1 43 34 37 35 17 NA NA NA NA NA NA 44659 XR_006395693.1 93 29 80 9 103 NA NA NA NA NA NA 44660 XM_044312619.1 5209 4550 2757 4440 4520 Q01085 6.85e-63 Nucleolysin TIAR (TIA-1-related protein) Homo sapiens (Human) apoptotic process [GO:0006915]; defense response [GO:0006952]; germ cell development [GO:0007281]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of hippo signaling [GO:0035332]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; positive regulation of stem cell proliferation [GO:2000648]; regulation of transcription by RNA polymerase II [GO:0006357]; stem cell division [GO:0017145]; stem cell proliferation [GO:0072089] GO:0003677; GO:0003723; GO:0003730; GO:0005634; GO:0005654; GO:0005737; GO:0005764; GO:0006357; GO:0006915; GO:0006952; GO:0007281; GO:0008285; GO:0010494; GO:0017145; GO:0035332; GO:0035925; GO:0044194; GO:0072089; GO:0140517; GO:2000637; GO:2000648 44661 XM_044312094.1 2 0 12 16 37 Q99MW1 5.5e-30 Serine/threonine-protein kinase 31 (EC 2.7.11.1) Mus musculus (Mouse) protein phosphorylation [GO:0006468] GO:0001669; GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0006468; GO:0106310 44662 XR_006396930.1 0 0 5 0 36 NA NA NA NA NA NA 44663 XM_029354349.2 1640 1613 851 1675 1893 Q9EQQ9 2.23e-120 Protein O-GlcNAcase (OGA) (EC 3.2.1.169) (Beta-N-acetylhexosaminidase) (Beta-hexosaminidase) (Bifunctional protein NCOAT) (Meningioma-expressed antigen 5) (N-acetyl-beta-D-glucosaminidase) (N-acetyl-beta-glucosaminidase) Mus musculus (Mouse) dATP metabolic process [GO:0046060]; glycoprotein metabolic process [GO:0009100]; N-acetylglucosamine metabolic process [GO:0006044]; necrotic cell death [GO:0070265]; negative regulation of cardiac muscle adaptation [GO:0010616]; negative regulation of protein glycosylation [GO:0060051]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of cell killing [GO:0031343]; positive regulation of DNA metabolic process [GO:0051054]; positive regulation of glucose import [GO:0046326]; positive regulation of growth hormone secretion [GO:0060124]; positive regulation of insulin secretion [GO:0032024]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of protein-containing complex disassembly [GO:0043243]; positive regulation of proteolysis [GO:0045862]; protein deglycosylation [GO:0006517]; protein targeting to membrane [GO:0006612] GO:0004402; GO:0005634; GO:0005739; GO:0005829; GO:0006044; GO:0006517; GO:0006612; GO:0009100; GO:0010524; GO:0010616; GO:0016231; GO:0031343; GO:0032024; GO:0042802; GO:0043243; GO:0045862; GO:0046060; GO:0046326; GO:0051054; GO:0051901; GO:0051928; GO:0060051; GO:0060124; GO:0070265; GO:0102166; GO:0102167; GO:0102571 44664 XM_029354349.2 1640 1613 851 1675 1893 Q9EQQ9 3.12e-71 Protein O-GlcNAcase (OGA) (EC 3.2.1.169) (Beta-N-acetylhexosaminidase) (Beta-hexosaminidase) (Bifunctional protein NCOAT) (Meningioma-expressed antigen 5) (N-acetyl-beta-D-glucosaminidase) (N-acetyl-beta-glucosaminidase) Mus musculus (Mouse) dATP metabolic process [GO:0046060]; glycoprotein metabolic process [GO:0009100]; N-acetylglucosamine metabolic process [GO:0006044]; necrotic cell death [GO:0070265]; negative regulation of cardiac muscle adaptation [GO:0010616]; negative regulation of protein glycosylation [GO:0060051]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of cell killing [GO:0031343]; positive regulation of DNA metabolic process [GO:0051054]; positive regulation of glucose import [GO:0046326]; positive regulation of growth hormone secretion [GO:0060124]; positive regulation of insulin secretion [GO:0032024]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of protein-containing complex disassembly [GO:0043243]; positive regulation of proteolysis [GO:0045862]; protein deglycosylation [GO:0006517]; protein targeting to membrane [GO:0006612] GO:0004402; GO:0005634; GO:0005739; GO:0005829; GO:0006044; GO:0006517; GO:0006612; GO:0009100; GO:0010524; GO:0010616; GO:0016231; GO:0031343; GO:0032024; GO:0042802; GO:0043243; GO:0045862; GO:0046060; GO:0046326; GO:0051054; GO:0051901; GO:0051928; GO:0060051; GO:0060124; GO:0070265; GO:0102166; GO:0102167; GO:0102571 44665 XM_029333116.2 3116 2573 1523 1447 1462 Q28DV3 0 Histone deacetylase 3 (HD3) (EC 3.5.1.98) (Protein deacetylase HDAC3) (EC 3.5.1.-) (Protein deacylase HDAC3) (EC 3.5.1.-) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) chromatin organization [GO:0006325]; circadian regulation of gene expression [GO:0032922]; histone deacetylation [GO:0016575]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of circadian rhythm [GO:0042752] GO:0000122; GO:0003682; GO:0003714; GO:0004407; GO:0005634; GO:0005737; GO:0006325; GO:0016575; GO:0017053; GO:0032922; GO:0042752; GO:0160008; GO:0160009; GO:0160010 44666 XR_006395464.1 148 64 112 194 291 A0A1D5NSM8 2.82e-32 NA NA NA NA 44667 XR_006395464.1 148 64 112 194 291 A0A1D5NSM8 7.82e-21 NA NA NA NA 44668 XM_029331867.2 139 323 454 635 332 A2CEI6 0 Piwi-like protein 2 (EC 3.1.26.-) Danio rerio (Zebrafish) (Brachydanio rerio) DNA methylation involved in gamete generation [GO:0043046]; gamete generation [GO:0007276]; germ-line stem cell population maintenance [GO:0030718]; meiotic cell cycle [GO:0051321]; negative regulation of SMAD protein complex assembly [GO:0010991]; negative regulation of transposition [GO:0010529]; oogenesis [GO:0048477]; piRNA processing [GO:0034587]; positive regulation of gene expression [GO:0010628]; regulation of translation [GO:0006417]; rhythmic process [GO:0048511]; RNA 5'-end processing [GO:0000966]; RNA-mediated gene silencing [GO:0031047]; spermatogenesis [GO:0007283] GO:0000966; GO:0003723; GO:0004521; GO:0005634; GO:0005737; GO:0006417; GO:0007276; GO:0007283; GO:0010529; GO:0010628; GO:0010991; GO:0030718; GO:0031047; GO:0034584; GO:0034587; GO:0043046; GO:0043186; GO:0046872; GO:0048477; GO:0048511; GO:0051321; GO:0071546; GO:1990923 44669 XR_006396562.1 37 0 30 22 14 NA NA NA NA NA NA 44670 XM_029356190.2 22 0 0 5 26 NA NA NA NA NA NA 44671 XM_029345960.1 49 9 34 43 29 NA NA NA NA NA NA 44672 XM_044319467.1 49 78 95 79 48 P0CI65 9.97e-48 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 44673 XM_044319467.1 49 78 95 79 48 P0CI65 8.89e-42 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 44674 XM_044319467.1 49 78 95 79 48 P0CI65 1.94e-39 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 44675 XM_044319467.1 49 78 95 79 48 P0CI65 9.88e-36 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 44676 XM_044319467.1 49 78 95 79 48 P0CI65 9.43e-28 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 44677 XM_044318750.1 1274 134 252 418 1158 NA NA NA NA NA NA 44678 XM_044320676.1 1 5 35 0 8 A2AJ76 6.21e-39 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 44679 XM_044320676.1 1 5 35 0 8 A2AJ76 1.08e-34 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 44680 XM_044320676.1 1 5 35 0 8 A2AJ76 2.52e-34 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 44681 XM_044320676.1 1 5 35 0 8 A2AJ76 1.41e-30 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 44682 XM_044320676.1 1 5 35 0 8 A2AJ76 2.69e-30 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 44683 XM_044320676.1 1 5 35 0 8 A2AJ76 2.23e-29 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 44684 XM_044320676.1 1 5 35 0 8 A2AJ76 3.31e-29 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 44685 XM_044320676.1 1 5 35 0 8 A2AJ76 1.3e-28 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 44686 XM_044320676.1 1 5 35 0 8 A2AJ76 1.72e-28 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 44687 XM_044320676.1 1 5 35 0 8 A2AJ76 2.66e-28 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 44688 XM_044320676.1 1 5 35 0 8 A2AJ76 1.55e-27 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 44689 XM_044320676.1 1 5 35 0 8 A2AJ76 8.02e-26 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 44690 XM_044320676.1 1 5 35 0 8 A2AJ76 2.63e-25 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 44691 XM_044320676.1 1 5 35 0 8 A2AJ76 2.79e-25 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 44692 XM_044320676.1 1 5 35 0 8 A2AJ76 5.3e-25 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 44693 XM_044320676.1 1 5 35 0 8 A2AJ76 1.14e-23 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 44694 XM_044320676.1 1 5 35 0 8 A2AJ76 2.51e-23 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 44695 XM_044320676.1 1 5 35 0 8 A2AJ76 3.53e-23 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 44696 XM_029323628.2 1327 580 410 854 1094 Q2VPA6 0 Helicase POLQ-like (EC 3.6.4.12) (Mus308-like helicase) (POLQ-like helicase) Mus musculus (Mouse) DNA double-strand break processing involved in repair via single-strand annealing [GO:0010792]; DNA metabolic process [GO:0006259]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via synthesis-dependent strand annealing [GO:0045003]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; rRNA processing [GO:0006364] GO:0000724; GO:0003677; GO:0005524; GO:0005634; GO:0006259; GO:0006364; GO:0010792; GO:0016887; GO:0017116; GO:0017117; GO:0045003; GO:0090734; GO:0097681; GO:1905168; GO:1990518 44697 XM_044315788.1 40 14 7 0 10 O60290 2.02e-64 Zinc finger protein 862 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006355; GO:0046872; GO:0046983 44698 XM_044323402.1 124 0 26 81 24 Q9JM13 8.35e-96 Rab5 GDP/GTP exchange factor (Rabex-5) Mus musculus (Mouse) dendritic transport [GO:0098935]; establishment of localization in cell [GO:0051649]; Kit signaling pathway [GO:0038109]; mast cell degranulation [GO:0043303]; mast cell migration [GO:0097531]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of Kit signaling pathway [GO:1900235]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of mast cell activation [GO:0033004]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; negative regulation of receptor-mediated endocytosis [GO:0048261]; protein phosphorylation [GO:0006468]; protein targeting to membrane [GO:0006612]; Ras protein signal transduction [GO:0007265]; receptor-mediated endocytosis [GO:0006898]; regulation of Fc receptor mediated stimulatory signaling pathway [GO:0060368] GO:0001933; GO:0002686; GO:0003677; GO:0005085; GO:0005730; GO:0005769; GO:0005829; GO:0006468; GO:0006612; GO:0006898; GO:0007265; GO:0008270; GO:0030139; GO:0030425; GO:0031267; GO:0031982; GO:0032715; GO:0032764; GO:0033004; GO:0038109; GO:0043303; GO:0043305; GO:0046580; GO:0048261; GO:0050728; GO:0051649; GO:0055037; GO:0060368; GO:0061630; GO:0097531; GO:0098935; GO:1900235 44699 XM_044322847.1 406 190 180 389 419 Q8R1N0 5.97e-35 Zinc finger protein 830 (Coiled-coil domain-containing protein 16) (Ovus mutant candidate gene 1 protein) Mus musculus (Mouse) blastocyst growth [GO:0001832]; cell division [GO:0051301]; chromosome organization [GO:0051276]; intestinal epithelial structure maintenance [GO:0060729]; mitotic cell cycle [GO:0000278]; mitotic DNA damage checkpoint signaling [GO:0044773]; mitotic DNA replication checkpoint signaling [GO:0033314]; mRNA processing [GO:0006397]; negative regulation of apoptotic process [GO:0043066]; nuclear DNA replication [GO:0033260]; ovarian follicle development [GO:0001541]; preantral ovarian follicle growth [GO:0001546]; replication fork protection [GO:0048478]; RNA splicing [GO:0008380] GO:0000278; GO:0001541; GO:0001546; GO:0001832; GO:0003676; GO:0005634; GO:0005681; GO:0005694; GO:0006397; GO:0008270; GO:0008380; GO:0016607; GO:0033260; GO:0033314; GO:0043066; GO:0044773; GO:0048478; GO:0051276; GO:0051301; GO:0060729 44700 XM_044328057.1 0 8 8 0 21 NA NA NA NA NA NA 44701 XR_006397310.1 53 8 33 29 61 NA NA NA NA NA NA 44702 XM_029327378.2 116 72 65 116 55 E7FAM5 8.83e-122 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 44703 XM_044307006.1 595 392 491 941 438 Q99986 2.15e-109 Serine/threonine-protein kinase VRK1 (EC 2.7.11.1) (Vaccinia-related kinase 1) Homo sapiens (Human) cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; Golgi disassembly [GO:0090166]; mitotic nuclear membrane disassembly [GO:0007077]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of protein localization to chromatin [GO:0120187]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165] GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005795; GO:0005829; GO:0006468; GO:0006974; GO:0007077; GO:0007165; GO:0018105; GO:0019901; GO:0035175; GO:0042393; GO:0046777; GO:0051301; GO:0072354; GO:0090166; GO:0106310; GO:0120187 44704 XM_029347685.2 432 179 212 288 325 Q9EP89 1.04e-117 Serine beta-lactamase-like protein LACTB, mitochondrial (EC 3.4.-.-) Mus musculus (Mouse) lipid metabolic process [GO:0006629]; proteolysis [GO:0006508]; regulation of lipid metabolic process [GO:0019216] GO:0005739; GO:0005829; GO:0006508; GO:0006629; GO:0008233; GO:0019216; GO:0042802 44705 XM_029332253.2 108 22 16 63 46 NA NA NA NA NA NA 44706 XM_029345130.2 0 0 0 0 41 NA NA NA NA NA NA 44707 XM_029323460.2 30 1 57 5 242 NA NA NA NA NA NA 44708 XM_044321781.1 0 0 0 0 29 NA NA NA NA NA NA 44709 XM_044327424.1 26 71 163 75 0 P50130 4.68e-38 D(1A) dopamine receptor (Dopamine D1 receptor) Sus scrofa (Pig) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; vasodilation [GO:0042311] GO:0004930; GO:0004952; GO:0005789; GO:0005886; GO:0007189; GO:0042311; GO:0043197 44710 XM_044313776.1 0 88 7 24 106 P55115 5.54e-38 Zinc metalloproteinase nas-15 (EC 3.4.24.-) (Nematode astacin 15) Caenorhabditis elegans proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0006508; GO:0008270 44711 XM_044309546.1 62 0 8 1 114 Q90953 4.19e-21 Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Large fibroblast proteoglycan) (PG-M) Gallus gallus (Chicken) cell adhesion [GO:0007155]; central nervous system development [GO:0007417]; skeletal system development [GO:0001501] GO:0001501; GO:0001750; GO:0005509; GO:0005540; GO:0005576; GO:0007155; GO:0007417; GO:0030246; GO:0031012; GO:0033165 44712 XM_044319713.1 673 318 210 380 238 Q23915 2.86e-24 Probable serine/threonine-protein kinase kinX (EC 2.7.11.1) Dictyostelium discoideum (Social amoeba) protein phosphorylation [GO:0006468]; signal transduction [GO:0007165] GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0006468; GO:0007165; GO:0106310 44713 XM_044317081.1 0 47 0 9 17 NA NA NA NA NA NA 44714 XM_029341846.2 2409 1875 1449 4993 3801 NA NA NA NA NA NA 44715 XM_044328126.1 306 0 0 0 0 C3YWU0 0 Alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucoside fucohydrolase) Branchiostoma floridae (Florida lancelet) (Amphioxus) fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139] GO:0004560; GO:0005576; GO:0005764; GO:0006004; GO:0016139 44716 XM_029333375.2 420 826 68 321 143 NA NA NA NA NA NA 44717 XM_044313321.1 255 64 73 291 54 NA NA NA NA NA NA 44718 XM_044310814.1 0 0 19 20 2 NA NA NA NA NA NA 44719 XM_029335698.2 278 162 94 215 352 Q9Z104 2.05e-28 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (SMARCE1-related protein) (BRCA2-associated factor 35) (HMG box-containing protein 20B) (Structural DNA-binding protein BRAF35) Mus musculus (Mouse) cell cycle [GO:0007049]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of protein sumoylation [GO:0033234]; positive regulation of neuron differentiation [GO:0045666]; protein sumoylation [GO:0016925]; regulation of DNA-templated transcription [GO:0006355]; regulation of gene expression [GO:0010468]; skeletal muscle cell differentiation [GO:0035914] GO:0000400; GO:0000794; GO:0002111; GO:0003677; GO:0005634; GO:0005654; GO:0006325; GO:0006338; GO:0006355; GO:0007049; GO:0010468; GO:0016604; GO:0016925; GO:0033234; GO:0035914; GO:0045666 44720 XM_029329208.2 0 42 0 147 0 NA NA NA NA NA NA 44721 XM_044324156.1 95 2 5 0 5 Q61655 3.69e-90 ATP-dependent RNA helicase DDX19A (EC 3.6.4.13) (DEAD box RNA helicase DEAD5) (mDEAD5) (DEAD box protein 19A) (Eukaryotic translation initiation factor 4A-related sequence 1) Mus musculus (Mouse) poly(A)+ mRNA export from nucleus [GO:0016973]; positive regulation of apoptotic process [GO:0043065]; response to zinc ion [GO:0010043] GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005654; GO:0010043; GO:0010494; GO:0016887; GO:0016973; GO:0043065 44722 XR_006393760.1 149 0 197 2 244 NA NA NA NA NA NA 44723 XM_044322024.1 0 32 0 0 0 P09487 1.54e-135 Alkaline phosphatase, tissue-nonspecific isozyme (AP-TNAP) (TNAP) (TNSALP) (EC 3.1.3.1) (Alkaline phosphatase liver/bone/kidney isozyme) (Phosphoamidase) (Phosphocreatine phosphatase) (EC 3.9.1.1) Bos taurus (Bovine) biomineral tissue development [GO:0031214]; bone mineralization [GO:0030282]; calcium ion homeostasis [GO:0055074]; cellular homeostasis [GO:0019725]; cellular response to organic cyclic compound [GO:0071407]; dephosphorylation [GO:0016311]; developmental process involved in reproduction [GO:0003006]; endochondral ossification [GO:0001958]; multicellular organism aging [GO:0010259]; phosphate ion homeostasis [GO:0055062]; positive regulation of cold-induced thermogenesis [GO:0120162]; pyridoxal phosphate metabolic process [GO:0042822]; response to antibiotic [GO:0046677]; response to sodium phosphate [GO:1904383]; response to vitamin B6 [GO:0034516]; response to vitamin D [GO:0033280] GO:0001958; GO:0003006; GO:0004035; GO:0004427; GO:0005509; GO:0005758; GO:0005886; GO:0010259; GO:0016311; GO:0016462; GO:0016887; GO:0019725; GO:0030282; GO:0031012; GO:0031214; GO:0031966; GO:0033280; GO:0033883; GO:0034516; GO:0042822; GO:0043262; GO:0046677; GO:0050187; GO:0052732; GO:0055062; GO:0055074; GO:0065010; GO:0071407; GO:0120162; GO:1904383 44724 XM_044318860.1 1 0 0 19 23 NA NA NA NA NA NA 44725 XM_044319660.1 999 531 574 724 339 Q00685 3.16e-143 Complement C3 [Cleaved into: Complement C3 beta chain; Complement C3 alpha chain; C3a anaphylatoxin; Complement C3 gamma chain] Lethenteron camtschaticum (Japanese lamprey) (Lampetra japonica) complement activation, classical pathway [GO:0006958]; inflammatory response [GO:0006954]; innate immune response [GO:0045087] GO:0004866; GO:0005615; GO:0006954; GO:0006958; GO:0045087 44726 XM_044319660.1 999 531 574 724 339 Q00685 4.08e-24 Complement C3 [Cleaved into: Complement C3 beta chain; Complement C3 alpha chain; C3a anaphylatoxin; Complement C3 gamma chain] Lethenteron camtschaticum (Japanese lamprey) (Lampetra japonica) complement activation, classical pathway [GO:0006958]; inflammatory response [GO:0006954]; innate immune response [GO:0045087] GO:0004866; GO:0005615; GO:0006954; GO:0006958; GO:0045087 44727 XM_029329684.2 1014 394 682 543 136 Q8BW96 2.18e-149 Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase I delta) (CaM-KI delta) (CaMKI delta) (CaM kinase ID) (CaMKI-like protein kinase) (CKLiK) (mCKLiK) Mus musculus (Mouse) inflammatory response [GO:0006954]; negative regulation of apoptotic process [GO:0043066]; nervous system development [GO:0007399]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of neuron projection development [GO:0010976]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of phagocytosis [GO:0050766]; positive regulation of respiratory burst [GO:0060267]; regulation of dendrite development [GO:0050773]; regulation of granulocyte chemotaxis [GO:0071622] GO:0004683; GO:0005516; GO:0005524; GO:0005634; GO:0005737; GO:0006954; GO:0007399; GO:0010976; GO:0018105; GO:0032793; GO:0043065; GO:0043066; GO:0050766; GO:0050773; GO:0060267; GO:0071622; GO:0090023; GO:0106310 44728 XM_029344714.2 274 59 90 225 357 Q5U403 7.52e-136 Diphosphomevalonate decarboxylase (EC 4.1.1.33) (Mevalonate (diphospho)decarboxylase) (MDDase) (Mevalonate pyrophosphate decarboxylase) Danio rerio (Zebrafish) (Brachydanio rerio) cholesterol biosynthetic process [GO:0006695]; isopentenyl diphosphate biosynthetic process, mevalonate pathway [GO:0019287] GO:0004163; GO:0005524; GO:0005829; GO:0006695; GO:0019287 44729 XM_044324645.1 0 0 0 0 16 A2AJ76 1.35e-27 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 44730 XM_044318773.1 61 68 84 35 469 NA NA NA NA NA NA 44731 XM_044323055.1 300 533 356 664 248 Q5IS54 4.59e-39 Caspase-3 (CASP-3) (EC 3.4.22.56) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12] Pan troglodytes (Chimpanzee) anterior neural tube closure [GO:0061713]; apoptotic process [GO:0006915]; B cell homeostasis [GO:0001782]; cell fate commitment [GO:0045165]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to staurosporine [GO:0072734]; epithelial cell apoptotic process [GO:1904019]; erythrocyte differentiation [GO:0030218]; fibroblast apoptotic process [GO:0044346]; glial cell apoptotic process [GO:0034349]; heart development [GO:0007507]; intrinsic apoptotic signaling pathway in response to osmotic stress [GO:0008627]; keratinocyte differentiation [GO:0030216]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of B cell proliferation [GO:0030889]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of protein stability [GO:0031647]; response to UV [GO:0009411]; response to wounding [GO:0009611]; sensory perception of sound [GO:0007605]; T cell homeostasis [GO:0043029] GO:0001782; GO:0004175; GO:0004190; GO:0004861; GO:0005634; GO:0005737; GO:0005829; GO:0006508; GO:0006915; GO:0006974; GO:0007507; GO:0007605; GO:0008627; GO:0009411; GO:0009611; GO:0016485; GO:0030182; GO:0030216; GO:0030218; GO:0030889; GO:0031647; GO:0034349; GO:0043029; GO:0043065; GO:0044346; GO:0045165; GO:0046007; GO:0048011; GO:0051402; GO:0061713; GO:0072734; GO:0097153; GO:0097199; GO:0097200; GO:1902004; GO:1904019 44732 XM_029342082.2 150 230 97 267 410 Q9NP66 2.4e-64 High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein 1) (HMG domain-containing protein HMGX1) Homo sapiens (Human) chromatin organization [GO:0006325]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355]; regulation of gene expression [GO:0010468] GO:0000122; GO:0003677; GO:0005634; GO:0006325; GO:0006355; GO:0010468; GO:0033234; GO:0042802; GO:0045665 44733 XM_044328415.1 26 13 0 18 12 Q96AY4 7.53e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44734 XM_044328415.1 26 13 0 18 12 Q96AY4 3.95e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44735 XM_044328415.1 26 13 0 18 12 Q96AY4 3.85e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44736 XM_044328415.1 26 13 0 18 12 Q96AY4 3.96e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44737 XM_044328415.1 26 13 0 18 12 Q96AY4 9.94e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44738 XM_044328415.1 26 13 0 18 12 Q96AY4 5.43e-37 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44739 XM_044328415.1 26 13 0 18 12 Q96AY4 3.16e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44740 XM_044328415.1 26 13 0 18 12 Q96AY4 3.72e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44741 XM_044328415.1 26 13 0 18 12 Q96AY4 2.95e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44742 XM_044328415.1 26 13 0 18 12 Q96AY4 3.84e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44743 XM_044328415.1 26 13 0 18 12 Q96AY4 2.64e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44744 XM_044328415.1 26 13 0 18 12 Q96AY4 9.51e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44745 XM_044328415.1 26 13 0 18 12 Q96AY4 1.63e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44746 XM_029339422.2 34 34 0 0 39 NA NA NA NA NA NA 44747 XM_044317409.1 0 0 0 28 0 F1PZV2 7.12e-21 Major facilitator superfamily domain-containing protein 12 Canis lupus familiaris (Dog) (Canis familiaris) carbohydrate transport [GO:0008643]; cysteine transmembrane transport [GO:1903712]; melanin biosynthetic process [GO:0042438]; organic substance transport [GO:0071702]; pigment metabolic process involved in pigmentation [GO:0043474]; regulation of melanin biosynthetic process [GO:0048021] GO:0005764; GO:0005765; GO:0005886; GO:0008643; GO:0015293; GO:0033162; GO:0033229; GO:0042438; GO:0043474; GO:0048021; GO:0071702; GO:1903712 44748 XM_029336540.2 108 98 91 184 493 P30531 1.27e-150 Sodium- and chloride-dependent GABA transporter 1 (GAT-1) (Solute carrier family 6 member 1) Homo sapiens (Human) associative learning [GO:0008306]; chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid import [GO:0051939]; gamma-aminobutyric acid reuptake [GO:0051936]; inorganic anion import across plasma membrane [GO:0098658]; memory [GO:0007613]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; positive regulation of gamma-aminobutyric acid secretion [GO:0014054]; response to calcium ion [GO:0051592]; response to cocaine [GO:0042220]; response to estradiol [GO:0032355]; response to inorganic substance [GO:0010035]; response to lead ion [GO:0010288]; response to purine-containing compound [GO:0014074]; response to sucrose [GO:0009744]; response to toxic substance [GO:0009636]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725]; synapse organization [GO:0050808]; transport across blood-brain barrier [GO:0150104] GO:0005332; GO:0005886; GO:0007268; GO:0007613; GO:0008306; GO:0009636; GO:0009744; GO:0009986; GO:0010035; GO:0010288; GO:0014054; GO:0014074; GO:0015185; GO:0015378; GO:0016020; GO:0030424; GO:0032229; GO:0032355; GO:0035725; GO:0042220; GO:0042734; GO:0042802; GO:0043005; GO:0043025; GO:0045211; GO:0046872; GO:0050808; GO:0051592; GO:0051936; GO:0051939; GO:0098658; GO:0098719; GO:0098982; GO:0150104; GO:1902476 44749 XM_044323490.1 3 28 29 0 23 NA NA NA NA NA NA 44750 XR_006397295.1 236 1294 141 546 1274 NA NA NA NA NA NA 44751 XM_044310722.1 0 0 5 0 7 Q09575 2.26e-40 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 44752 XM_044325376.1 2 85 55 15 51 NA NA NA NA NA NA 44753 XM_044329293.1 0 28 0 35 17 Q9P2P6 4.28e-21 StAR-related lipid transfer protein 9 (START domain-containing protein 9) (StARD9) Homo sapiens (Human) microtubule-based movement [GO:0007018]; spindle assembly [GO:0051225] GO:0003777; GO:0005524; GO:0005634; GO:0005737; GO:0005814; GO:0007018; GO:0008017; GO:0008289; GO:0051225 44754 XM_044325152.1 478 214 229 195 197 O77649 3.26e-64 UDP-glucuronosyltransferase 2B20 (UDPGT 2B20) (EC 2.4.1.17) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0005789; GO:0015020 44755 XR_006395176.1 184 402 219 228 130 NA NA NA NA NA NA 44756 XM_044322925.1 824 662 475 804 873 NA NA NA NA NA NA 44757 XM_044321564.1 543 198 253 500 544 Q14108 1.33e-80 Lysosome membrane protein 2 (85 kDa lysosomal membrane sialoglycoprotein) (LGP85) (CD36 antigen-like 2) (Lysosome membrane protein II) (LIMP II) (Scavenger receptor class B member 2) (CD antigen CD36) Homo sapiens (Human) aminophospholipid transport [GO:0015917]; gene expression [GO:0010467]; positive regulation of neuron projection development [GO:0010976]; protein targeting to lysosome [GO:0006622]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular carbohydrate catabolic process [GO:0043471]; regulation of endosome organization [GO:1904978]; regulation of glucosylceramidase activity [GO:1905123]; regulation of lysosome organization [GO:1905671]; sensory perception of sound [GO:0007605] GO:0000139; GO:0001618; GO:0001786; GO:0004888; GO:0005044; GO:0005737; GO:0005765; GO:0005789; GO:0005886; GO:0005925; GO:0006622; GO:0006898; GO:0007605; GO:0010008; GO:0010467; GO:0010976; GO:0015485; GO:0015917; GO:0016020; GO:0019899; GO:0030666; GO:0030669; GO:0031210; GO:0031902; GO:0038024; GO:0042803; GO:0043202; GO:0043471; GO:0051087; GO:0070062; GO:1904978; GO:1905123; GO:1905671 44758 XM_044307196.1 409 835 184 285 405 O07834 3.07e-114 Dipeptidyl aminopeptidase BI (DAP BI) (EC 3.4.14.-) Pseudoxanthomonas mexicana proteolysis involved in protein catabolic process [GO:0051603] GO:0004177; GO:0004252; GO:0008239; GO:0051603 44759 XM_044311892.1 129 5 41 101 66 NA NA NA NA NA NA 44760 XM_044312699.1 323 152 114 253 239 Q5ZK28 2.89e-39 DNA polymerase delta subunit 3 (DNA polymerase delta subunit p66) Gallus gallus (Chicken) DNA strand elongation involved in DNA replication [GO:0006271]; DNA synthesis involved in UV-damage excision repair [GO:1904161]; nucleotide-excision repair, DNA gap filling [GO:0006297] GO:0005654; GO:0005737; GO:0006271; GO:0006297; GO:0043625; GO:1904161 44761 XM_044308293.1 21 18 9 74 96 NA NA NA NA NA NA 44762 XM_029357614.2 459 569 428 407 383 O75817 5.61e-29 Ribonuclease P protein subunit p20 (RNaseP protein p20) (Ribonucleases P/MRP protein subunit POP7 homolog) (hPOP7) Homo sapiens (Human) RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; rRNA processing [GO:0006364]; tRNA 5'-leader removal [GO:0001682]; tRNA processing [GO:0008033] GO:0000172; GO:0001682; GO:0003723; GO:0004526; GO:0005634; GO:0005654; GO:0005655; GO:0005730; GO:0005737; GO:0006364; GO:0008033; GO:0030681; GO:0033204; GO:0043231; GO:0090502 44763 XM_044314856.1 1 0 9 0 92 NA NA NA NA NA NA 44764 XM_029333475.2 105 191 50 65 116 Q9DFZ4 1.68e-37 Protein Churchill Xenopus laevis (African clawed frog) positive regulation of DNA-templated transcription [GO:0045893] GO:0008270; GO:0045893 44765 XM_044307181.1 53 2 38 11 35 NA NA NA NA NA NA 44766 XM_044327643.1 22 1 0 8 0 Q2M3R5 2.12e-46 Solute carrier family 35 member G1 (Partner of STIM1) (Transmembrane protein 20) Homo sapiens (Human) calcium ion export across plasma membrane [GO:1990034]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0005789; GO:0005886; GO:0016020; GO:0051480; GO:1990034 44767 XM_029355924.2 189 129 89 249 157 NA NA NA NA NA NA 44768 XM_029329945.2 0 6 2 0 28 P17971 1.74e-87 Potassium voltage-gated channel protein Shal (Shaker cognate l) (Shal2) Drosophila melanogaster (Fruit fly) associative learning [GO:0008306]; chemical synaptic transmission [GO:0007268]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005250; GO:0005886; GO:0006813; GO:0007268; GO:0008076; GO:0008306; GO:0016020; GO:0030425; GO:0034765; GO:0043204; GO:0045202; GO:0051260; GO:0071805 44769 XM_044316026.1 12 20 7 13 69 NA NA NA NA NA NA 44770 XR_006396178.1 268 270 176 277 184 NA NA NA NA NA NA 44771 XM_044321667.1 10 0 49 0 10 NA NA NA NA NA NA 44772 XM_044308751.1 0 0 28 0 0 Q8JGS1 3.74e-72 SCL-interrupting locus protein homolog Danio rerio (Zebrafish) (Brachydanio rerio) body morphogenesis [GO:0010171]; centrosome duplication [GO:0051298]; mitotic spindle organization [GO:0007052]; neuron cellular homeostasis [GO:0070050]; positive regulation of centriole replication [GO:0046601]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of mitotic spindle organization [GO:0110028]; positive regulation of spindle assembly [GO:1905832]; protein localization to centrosome [GO:0071539]; regulation of centriole replication [GO:0046599]; smoothened signaling pathway [GO:0007224]; spindle assembly [GO:0051225] GO:0005737; GO:0005813; GO:0005814; GO:0007052; GO:0007224; GO:0010171; GO:0046599; GO:0046601; GO:0051225; GO:0051298; GO:0070050; GO:0071539; GO:0110028; GO:0120099; GO:1900087; GO:1905832 44773 XM_044328575.1 91 280 44 142 90 O43827 4.41e-35 Angiopoietin-related protein 7 (Angiopoietin-like factor) (Angiopoietin-like protein 7) (Cornea-derived transcript 6 protein) Homo sapiens (Human) negative regulation of vasculature development involved in avascular cornea development in camera-type eye [GO:1901346]; regulation of extracellular matrix organization [GO:1903053]; response to oxidative stress [GO:0006979] GO:0005102; GO:0005576; GO:0005615; GO:0006979; GO:0042802; GO:0062023; GO:1901346; GO:1903053 44774 XM_044315835.1 2 2 22 0 26 NA NA NA NA NA NA 44775 XM_044328477.1 156 173 115 187 206 NA NA NA NA NA NA 44776 XM_044322752.1 23 473 244 410 571 NA NA NA NA NA NA 44777 XM_029335020.2 126 0 20 141 90 Q84K35 3.93e-106 Pseudouridine-5'-phosphate glycosidase (PsiMP glycosidase) (EC 4.2.1.70) (Pseudouridine monophosphate glycosidase) Arabidopsis thaliana (Mouse-ear cress) NA GO:0004730; GO:0005777; GO:0030597; GO:0046872 44778 XM_029344546.2 245 181 130 343 245 NA NA NA NA NA NA 44779 XM_044308523.1 42 21 31 3 55 NA NA NA NA NA NA 44780 XM_029343385.2 0 128 155 130 186 NA NA NA NA NA NA 44781 XM_044307964.1 755 288 367 1037 975 Q6DFB8 0 Tetratricopeptide repeat protein 37 (TPR repeat protein 37) (Thespin homolog) Xenopus laevis (African clawed frog) RNA catabolic process [GO:0006401] GO:0000791; GO:0005634; GO:0005737; GO:0006401; GO:0055087 44782 XM_029345176.2 5016 4107 3976 3644 4008 O95164 4.23e-46 Ubiquitin-like protein 3 (Membrane-anchored ubiquitin-fold protein) (HsMUB) (MUB) (Protein HCG-1) Homo sapiens (Human) NA GO:0005886; GO:0070062 44783 XM_029343801.2 477 437 978 792 721 Q8CFV9 2.55e-63 Riboflavin kinase (EC 2.7.1.26) (ATP:riboflavin 5'-phosphotransferase) (Flavokinase) (KOI-4) Mus musculus (Mouse) apoptotic process [GO:0006915]; FMN biosynthetic process [GO:0009398]; phosphorylation [GO:0016310]; positive regulation of NAD(P)H oxidase activity [GO:0033864]; reactive oxygen species metabolic process [GO:0072593]; riboflavin biosynthetic process [GO:0009231]; riboflavin metabolic process [GO:0006771] GO:0005524; GO:0005739; GO:0006771; GO:0006915; GO:0008531; GO:0009231; GO:0009398; GO:0016310; GO:0033864; GO:0046872; GO:0072593 44784 XM_029347716.2 178 860 360 663 307 Q7YSW8 5.92e-53 Serine/threonine-protein phosphatase 2B catalytic subunit (EC 3.1.3.16) (Calcineurin subunit A) Dictyostelium discoideum (Social amoeba) calcineurin-mediated signaling [GO:0097720]; regulation of sorocarp development [GO:0031156]; response to cation stress [GO:0043157]; response to differentiation-inducing factor 1 [GO:1903013]; sorocarp spore cell differentiation [GO:0044671]; sorocarp stalk cell differentiation [GO:0031149] GO:0004722; GO:0005516; GO:0005737; GO:0005955; GO:0017018; GO:0031149; GO:0031156; GO:0033192; GO:0043157; GO:0044671; GO:0046872; GO:0097720; GO:1903013 44785 XM_044327074.1 184 119 116 240 274 NA NA NA NA NA NA 44786 XM_044320530.1 2049 4479 1666 3695 2476 NA NA NA NA NA NA 44787 XR_003826663.2 247 124 129 153 122 NA NA NA NA NA NA 44788 XM_044317468.1 7 20 8 79 0 NA NA NA NA NA NA 44789 XM_029330025.2 520 216 252 631 379 Q96MT7 0 Cilia- and flagella-associated protein 44 (WD repeat-containing protein 52) Homo sapiens (Human) cilium assembly [GO:0060271]; cilium-dependent cell motility [GO:0060285]; microtubule cytoskeleton organization [GO:0000226]; sperm axoneme assembly [GO:0007288] GO:0000226; GO:0005737; GO:0005856; GO:0007288; GO:0008233; GO:0031514; GO:0060271; GO:0060285 44790 XM_029330025.2 520 216 252 631 379 Q96MT7 4.85e-123 Cilia- and flagella-associated protein 44 (WD repeat-containing protein 52) Homo sapiens (Human) cilium assembly [GO:0060271]; cilium-dependent cell motility [GO:0060285]; microtubule cytoskeleton organization [GO:0000226]; sperm axoneme assembly [GO:0007288] GO:0000226; GO:0005737; GO:0005856; GO:0007288; GO:0008233; GO:0031514; GO:0060271; GO:0060285 44791 XM_029330025.2 520 216 252 631 379 Q96MT7 3.29e-55 Cilia- and flagella-associated protein 44 (WD repeat-containing protein 52) Homo sapiens (Human) cilium assembly [GO:0060271]; cilium-dependent cell motility [GO:0060285]; microtubule cytoskeleton organization [GO:0000226]; sperm axoneme assembly [GO:0007288] GO:0000226; GO:0005737; GO:0005856; GO:0007288; GO:0008233; GO:0031514; GO:0060271; GO:0060285 44792 XM_029339312.2 765 501 276 877 897 Q9JI13 1.94e-30 Something about silencing protein 10 (Charged amino acid-rich leucine zipper 1) (Crl-1) (Disrupter of silencing SAS10) (UTP3 homolog) Mus musculus (Mouse) brain development [GO:0007420]; chromatin organization [GO:0006325]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462] GO:0000462; GO:0005634; GO:0005730; GO:0006325; GO:0007420; GO:0032040 44793 XM_044320792.1 23 29 14 4 31 NA NA NA NA NA NA 44794 XM_029332669.2 887 518 527 1070 984 A8E7C5 0 Phosphatidylinositide phosphatase SAC2 (EC 3.1.3.25) (Inositol polyphosphate 5-phosphatase F) (Sac domain-containing inositol phosphatase 2) (Sac domain-containing phosphoinositide 4-phosphatase 2) (hSAC2) Danio rerio (Zebrafish) (Brachydanio rerio) clathrin-dependent endocytosis [GO:0072583]; phosphatidylinositol dephosphorylation [GO:0046856]; regulation of endocytic recycling [GO:2001135] GO:0005769; GO:0005905; GO:0008934; GO:0042803; GO:0043812; GO:0045334; GO:0046856; GO:0052832; GO:0052833; GO:0055037; GO:0072583; GO:2001135 44795 XM_029356103.2 311 167 188 401 222 NA NA NA NA NA NA 44796 XM_029352516.2 170 200 72 152 214 NA NA NA NA NA NA 44797 XM_044311231.1 6 0 4 0 3 NA NA NA NA NA NA 44798 XM_044322354.1 211 136 157 276 366 A9Z1V5 4.42e-83 von Willebrand factor A domain-containing protein 5B1 Mus musculus (Mouse) NA GO:0005576 44799 XM_029342236.2 756 735 460 989 504 O15350 3.43e-57 Tumor protein p73 (p53-like transcription factor) (p53-related protein) Homo sapiens (Human) cell cycle [GO:0007049]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of lung ciliated cell differentiation [GO:1901248]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein tetramerization [GO:0051262]; regulation of cell cycle [GO:0051726]; regulation of gene expression [GO:0010468]; regulation of mitotic cell cycle [GO:0007346]; regulation of transcription by RNA polymerase II [GO:0006357]; response to organonitrogen compound [GO:0010243]; response to xenobiotic stimulus [GO:0009410] GO:0000785; GO:0000976; GO:0000978; GO:0000981; GO:0001222; GO:0001228; GO:0001822; GO:0002039; GO:0003700; GO:0005634; GO:0005654; GO:0005794; GO:0005829; GO:0006298; GO:0006357; GO:0006974; GO:0007049; GO:0007346; GO:0008285; GO:0008630; GO:0009410; GO:0010243; GO:0010468; GO:0019901; GO:0030054; GO:0042771; GO:0042802; GO:0043065; GO:0043231; GO:0043410; GO:0045665; GO:0045893; GO:0045944; GO:0046872; GO:0048714; GO:0051262; GO:0051726; GO:0060044; GO:0061629; GO:0097371; GO:0140297; GO:1901248 44800 XM_029357100.2 218 150 216 232 325 Q7L0R7 8.18e-31 RING finger protein 44 Homo sapiens (Human) protein ubiquitination [GO:0016567] GO:0016567; GO:0046872; GO:0061630 44801 XM_029338722.2 246 172 113 158 369 NA NA NA NA NA NA 44802 XM_029329517.2 51 18 0 73 0 O70521 7.21e-32 Regulator of G-protein signaling 19 (RGS19) (G-alpha-interacting protein) (GAIP) Rattus norvegicus (Rat) negative regulation of signal transduction [GO:0009968]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; response to ethanol [GO:0045471] GO:0000139; GO:0001965; GO:0005096; GO:0005737; GO:0005903; GO:0008277; GO:0009968; GO:0016020; GO:0030136; GO:0045121; GO:0045471 44803 XM_029358445.2 41 7 2 40 6 Q6ZSM3 2.46e-24 Monocarboxylate transporter 12 (MCT 12) (Creatine transporter 2) (CRT2) (Solute carrier family 16 member 12) Homo sapiens (Human) creatine transmembrane transport [GO:0015881]; creatinine metabolic process [GO:0046449]; monocarboxylic acid transport [GO:0015718]; transport across blood-brain barrier [GO:0150104] GO:0005308; GO:0005886; GO:0008028; GO:0015292; GO:0015718; GO:0015881; GO:0016020; GO:0016323; GO:0046449; GO:0150104 44804 XM_044309005.1 17 41 0 0 0 NA NA NA NA NA NA 44805 XM_029328890.2 507 279 302 334 383 Q7Z2K6 5.84e-169 Endoplasmic reticulum metallopeptidase 1 (EC 3.4.-.-) (Felix-ina) Homo sapiens (Human) cellular response to oxidative stress [GO:0034599]; endoplasmic reticulum unfolded protein response [GO:0030968]; proteolysis [GO:0006508] GO:0005783; GO:0005789; GO:0006508; GO:0008235; GO:0016020; GO:0030968; GO:0034599; GO:0046872 44806 XM_029343328.2 32 34 10 306 87 NA NA NA NA NA NA 44807 XM_044321221.1 186 191 254 38 334 Q9QXW2 2.96e-36 F-box/WD repeat-containing protein 5 (F-box and WD-40 domain-containing protein 5) Mus musculus (Mouse) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of centrosome duplication [GO:0010824]; regulation of mitotic nuclear division [GO:0007088]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0005737; GO:0007088; GO:0010824; GO:0016567; GO:0019005; GO:0019901; GO:0031146; GO:0043161; GO:0080008 44808 XM_044321221.1 186 191 254 38 334 Q9QXW2 2.08e-30 F-box/WD repeat-containing protein 5 (F-box and WD-40 domain-containing protein 5) Mus musculus (Mouse) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of centrosome duplication [GO:0010824]; regulation of mitotic nuclear division [GO:0007088]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0005737; GO:0007088; GO:0010824; GO:0016567; GO:0019005; GO:0019901; GO:0031146; GO:0043161; GO:0080008 44809 XM_029331236.2 1706 3230 1883 2976 2193 A5PK71 2.39e-118 Parkin coregulated gene protein Bos taurus (Bovine) negative regulation of cell death [GO:0060548]; protein localization [GO:0008104]; spermatid development [GO:0007286] GO:0001664; GO:0002177; GO:0003779; GO:0005829; GO:0005879; GO:0007286; GO:0008104; GO:0030544; GO:0031625; GO:0031982; GO:0043005; GO:0043014; GO:0044297; GO:0048487; GO:0051087; GO:0051879; GO:0060548; GO:0097225 44810 XM_029326114.2 0 7 0 8 0 NA NA NA NA NA NA 44811 XM_044316548.1 6331 5336 3801 5854 5627 Q26614 3.27e-140 Fibroblast growth factor receptor (SpFGFR) (EC 2.7.10.1) Strongylocentrotus purpuratus (Purple sea urchin) positive regulation of kinase activity [GO:0033674]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0004714; GO:0005007; GO:0005524; GO:0005886; GO:0007169; GO:0017134; GO:0033674; GO:0043235 44812 XM_029350456.2 451 248 156 354 543 Q96D46 0 60S ribosomal export protein NMD3 (hNMD3) Homo sapiens (Human) positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to nucleolus [GO:1904751]; positive regulation of RNA biosynthetic process [GO:1902680]; protein transport [GO:0015031]; ribosomal large subunit export from nucleus [GO:0000055] GO:0000055; GO:0003723; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0015031; GO:0016020; GO:0030674; GO:0032092; GO:0043023; GO:1902680; GO:1904751 44813 XM_044308966.1 37 15 16 4 70 NA NA NA NA NA NA 44814 XM_044322107.1 2179 1001 739 1064 1457 Q9UA35 2.92e-148 Solute carrier family 28 member 3 (Concentrative Na(+)-nucleoside cotransporter 3) (hfCNT) Eptatretus stoutii (Pacific hagfish) NA GO:0005337; GO:0005886; GO:0015293 44815 XM_029335299.2 182 236 186 191 473 A2VDS1 1.95e-153 Selenocysteine lyase (EC 4.4.1.16) Bos taurus (Bovine) NA GO:0005794; GO:0005829; GO:0009000; GO:0016740 44816 XR_006398168.1 0 2 0 6 8 NA NA NA NA NA NA 44817 XM_044326943.1 0 9 1 0 5 NA NA NA NA NA NA 44818 XM_029340397.2 156 77 117 101 123 Q8IRC7 1.03e-76 LIM/homeobox protein Awh (Protein arrowhead) Drosophila melanogaster (Fruit fly) compound eye development [GO:0048749]; imaginal disc development [GO:0007444]; neuron differentiation [GO:0030182]; regulation of DNA-templated transcription [GO:0006355]; regulation of gene expression [GO:0010468]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000977; GO:0000981; GO:0003700; GO:0005634; GO:0006355; GO:0006357; GO:0007444; GO:0010468; GO:0030182; GO:0046872; GO:0048749 44819 XR_006397853.1 20 0 4 4 29 NA NA NA NA NA NA 44820 XM_029324508.2 680 518 310 455 324 P56873 5.82e-23 Protein ZNRD2 (Autoantigen p27 homolog) (Protein C184L) (Sjoegren syndrome/scleroderma autoantigen 1 homolog) (Zinc ribbon domain-containing protein 2) Mus musculus (Mouse) NA NA 44821 XR_003825154.2 17 17 1 22 30 NA NA NA NA NA NA 44822 XM_029346874.2 61 70 35 130 48 NA NA NA NA NA NA 44823 XM_029345379.2 1008 993 513 475 599 Q9DAA6 5.15e-79 Exosome complex component CSL4 (Exosome component 1) Mus musculus (Mouse) RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]; rRNA processing [GO:0006364] GO:0000176; GO:0000177; GO:0000178; GO:0003723; GO:0005634; GO:0005730; GO:0005737; GO:0005829; GO:0006364; GO:0006396; GO:0006401; GO:0101019 44824 XM_029342675.2 5613 8734 4382 6332 2554 Q8TDX7 2.17e-170 Serine/threonine-protein kinase Nek7 (EC 2.7.11.1) (Never in mitosis A-related kinase 7) (NimA-related protein kinase 7) Homo sapiens (Human) cellular response to potassium ion [GO:0035865]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of NLRP3 inflammasome complex assembly [GO:1900227]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein phosphorylation [GO:0006468]; regulation of mitotic cell cycle [GO:0007346]; spindle assembly [GO:0051225] GO:0000922; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005815; GO:0005874; GO:0006468; GO:0007346; GO:0018105; GO:0032212; GO:0035865; GO:0046872; GO:0051225; GO:0051973; GO:0106310; GO:0140677; GO:1900227; GO:1904355 44825 XR_003826489.2 0 2 4 0 7 NA NA NA NA NA NA 44826 XM_029331244.2 22 270 195 241 320 Q96D71 1.13e-25 RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1) Homo sapiens (Human) endocytosis [GO:0006897]; endosomal transport [GO:0016197] GO:0005509; GO:0005829; GO:0005886; GO:0005905; GO:0006897; GO:0016197; GO:0017124 44827 XM_029352766.2 0 0 3 0 9 Q09575 3.9e-56 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 44828 XM_029325512.2 75 130 100 69 98 NA NA NA NA NA NA 44829 XM_029343456.2 0 0 0 37 51 NA NA NA NA NA NA 44830 XM_044311146.1 0 6 0 0 0 NA NA NA NA NA NA 44831 XM_044326947.1 73 76 18 309 98 NA NA NA NA NA NA 44832 XM_029347330.2 1 7 7 7 23 P20664 5.67e-163 DNA primase small subunit (EC 2.7.7.102) (DNA primase 49 kDa subunit) (p49) Mus musculus (Mouse) DNA replication initiation [GO:0006270]; DNA replication, synthesis of RNA primer [GO:0006269] GO:0000287; GO:0003896; GO:0005658; GO:0006269; GO:0006270; GO:0008270; GO:0032553 44833 XM_029341603.2 21 10 0 2 8 NA NA NA NA NA NA 44834 XM_044320295.1 26 17 14 229 139 NA NA NA NA NA NA 44835 XR_003824124.2 20 25 27 26 292 NA NA NA NA NA NA 44836 XM_044325832.1 7 27 21 28 8 NA NA NA NA NA NA 44837 XM_044324441.1 3 0 0 8 5 NA NA NA NA NA NA 44838 XM_044308821.1 345 517 227 460 138 NA NA NA NA NA NA 44839 XM_044311019.1 874 485 167 637 304 Q2T9W7 4.45e-48 Motile sperm domain-containing protein 1 Bos taurus (Bovine) NA GO:0000139; GO:0005737; GO:0005789 44840 XM_029344368.2 0 0 44 70 0 NA NA NA NA NA NA 44841 XM_044319049.1 420 86 158 815 731 NA NA NA NA NA NA 44842 XM_029342421.2 13 0 177 0 0 O60930 3.42e-55 Ribonuclease H1 (RNase H1) (EC 3.1.26.4) (Ribonuclease H type II) Homo sapiens (Human) DNA replication, removal of RNA primer [GO:0043137]; RNA catabolic process [GO:0006401]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502] GO:0000287; GO:0003676; GO:0003723; GO:0004523; GO:0004540; GO:0005737; GO:0006401; GO:0043137; GO:0090502 44843 XM_029332698.2 96 0 39 21 70 Q68EA5 1e-50 Zinc finger protein 57 (Zinc finger protein 424) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000977; GO:0000981; GO:0005634; GO:0006357; GO:0046872 44844 XM_029332698.2 96 0 39 21 70 Q68EA5 7.36e-44 Zinc finger protein 57 (Zinc finger protein 424) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000977; GO:0000981; GO:0005634; GO:0006357; GO:0046872 44845 XM_029332698.2 96 0 39 21 70 Q68EA5 4.17e-43 Zinc finger protein 57 (Zinc finger protein 424) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000977; GO:0000981; GO:0005634; GO:0006357; GO:0046872 44846 XM_029332698.2 96 0 39 21 70 Q68EA5 4.75e-43 Zinc finger protein 57 (Zinc finger protein 424) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000977; GO:0000981; GO:0005634; GO:0006357; GO:0046872 44847 XM_029332698.2 96 0 39 21 70 Q68EA5 7.61e-43 Zinc finger protein 57 (Zinc finger protein 424) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000977; GO:0000981; GO:0005634; GO:0006357; GO:0046872 44848 XM_029332698.2 96 0 39 21 70 Q68EA5 4.79e-36 Zinc finger protein 57 (Zinc finger protein 424) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000977; GO:0000981; GO:0005634; GO:0006357; GO:0046872 44849 XM_029332698.2 96 0 39 21 70 Q68EA5 2.39e-32 Zinc finger protein 57 (Zinc finger protein 424) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000977; GO:0000981; GO:0005634; GO:0006357; GO:0046872 44850 XM_029332698.2 96 0 39 21 70 Q68EA5 1.14e-27 Zinc finger protein 57 (Zinc finger protein 424) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000977; GO:0000981; GO:0005634; GO:0006357; GO:0046872 44851 XM_044320290.1 204 88 127 235 243 NA NA NA NA NA NA 44852 XM_029340980.2 267 102 192 251 357 NA NA NA NA NA NA 44853 XM_029345261.2 0 0 0 0 119 Q5RFP4 1.93e-52 Zinc finger protein OZF (Only zinc finger protein) (Zinc finger protein 146) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 44854 XM_029345261.2 0 0 0 0 119 Q5RFP4 2.19e-44 Zinc finger protein OZF (Only zinc finger protein) (Zinc finger protein 146) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 44855 XR_006394365.1 26 5 32 11 29 NA NA NA NA NA NA 44856 XM_044322021.1 687 748 353 645 741 Q569B9 3.25e-68 Protein MFI (Mitochondrial fission factor interactor) (Protein C11orf65 homolog) Rattus norvegicus (Rat) negative regulation of mitochondrial fission [GO:0090258]; negative regulation of protein targeting to mitochondrion [GO:1903215] GO:0005741; GO:0005829; GO:0090258; GO:1903215 44857 XM_029338093.2 4475 5063 2799 3367 2416 Q5R7C5 1.77e-168 Erlin-2 (Endoplasmic reticulum lipid raft-associated protein 2) (Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2) (SPFH domain-containing protein 2) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cholesterol metabolic process [GO:0008203] GO:0005789; GO:0008203; GO:0031625 44858 XM_044324994.1 90 11 39 20 33 NA NA NA NA NA NA 44859 XR_006392441.1 29 1 43 4 61 NA NA NA NA NA NA 44860 XM_044316193.1 31 0 0 0 23 NA NA NA NA NA NA 44861 XM_029338214.2 3305 2291 1280 2649 2219 P42893 7.18e-121 Endothelin-converting enzyme 1 (ECE-1) (EC 3.4.24.71) Rattus norvegicus (Rat) apoptotic process [GO:0006915]; axonogenesis involved in innervation [GO:0060385]; blood vessel diameter maintenance [GO:0097746]; bradykinin catabolic process [GO:0010815]; calcitonin catabolic process [GO:0010816]; ear development [GO:0043583]; embryonic digit morphogenesis [GO:0042733]; embryonic heart tube development [GO:0035050]; endothelin maturation [GO:0034959]; gene expression [GO:0010467]; heart development [GO:0007507]; hormone catabolic process [GO:0042447]; neuron projection development [GO:0031175]; peptide hormone processing [GO:0016486]; pharyngeal system development [GO:0060037]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of receptor recycling [GO:0001921]; protein processing [GO:0016485]; regulation of blood pressure [GO:0008217]; regulation of ERK1 and ERK2 cascade [GO:0070372]; response to cadmium ion [GO:0046686]; response to hypoxia [GO:0001666]; response to muscle stretch [GO:0035994]; response to xenobiotic stimulus [GO:0009410]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; substance P catabolic process [GO:0010814]; sympathetic neuron axon guidance [GO:0097492] GO:0001666; GO:0001921; GO:0004175; GO:0004222; GO:0005768; GO:0005769; GO:0005886; GO:0006915; GO:0007507; GO:0008217; GO:0008270; GO:0009410; GO:0009897; GO:0010467; GO:0010613; GO:0010814; GO:0010815; GO:0010816; GO:0016020; GO:0016485; GO:0016486; GO:0030141; GO:0031175; GO:0031410; GO:0031982; GO:0033093; GO:0034959; GO:0035050; GO:0035994; GO:0042447; GO:0042733; GO:0042802; GO:0042803; GO:0043583; GO:0043950; GO:0045745; GO:0046686; GO:0048471; GO:0060037; GO:0060385; GO:0070372; GO:0097492; GO:0097746; GO:1902287 44862 XM_044324928.1 3 0 0 0 6 NA NA NA NA NA NA 44863 XM_029329289.2 2737 2422 2139 2232 2437 NA NA NA NA NA NA 44864 XM_029340228.2 125 237 158 369 386 NA NA NA NA NA NA 44865 XM_044324347.1 364 298 216 437 597 NA NA NA NA NA NA 44866 XM_029356816.2 107 131 126 126 26 NA NA NA NA NA NA 44867 XR_003826198.2 51 63 24 48 312 NA NA NA NA NA NA 44868 XM_029333115.2 937 836 562 889 953 Q5EA53 1.12e-39 General transcription factor IIF subunit 1 (Transcription initiation factor IIF subunit alpha) (TFIIF-alpha) Bos taurus (Bovine) negative regulation of protein binding [GO:0032091]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; response to virus [GO:0009615]; transcription elongation by RNA polymerase II promoter [GO:0006368]; transcription initiation at RNA polymerase II promoter [GO:0006367] GO:0001096; GO:0003677; GO:0005669; GO:0005674; GO:0006367; GO:0006368; GO:0009615; GO:0016251; GO:0019211; GO:0019903; GO:0019904; GO:0030054; GO:0032091; GO:0032968; GO:0045944; GO:1990841 44869 XM_044329001.1 0 12 10 18 20 Q8K2J9 3.76e-69 BTB/POZ domain-containing protein 6 Mus musculus (Mouse) neurogenesis [GO:0022008] GO:0005829; GO:0022008 44870 XM_044327778.1 2836 1564 1586 3570 3522 Q6ZWR6 1.2e-45 Nesprin-1 (Enaptin) (KASH domain-containing protein 1) (KASH1) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) Mus musculus (Mouse) centrosome localization [GO:0051642]; Golgi organization [GO:0007030]; muscle cell differentiation [GO:0042692]; nuclear matrix anchoring at nuclear membrane [GO:0090292]; nuclear migration [GO:0007097]; regulation of cilium assembly [GO:1902017]; spermatogenesis [GO:0007283] GO:0000932; GO:0003779; GO:0005521; GO:0005635; GO:0005640; GO:0005654; GO:0005730; GO:0005737; GO:0005794; GO:0005856; GO:0007030; GO:0007097; GO:0007283; GO:0016020; GO:0019899; GO:0030017; GO:0031965; GO:0034993; GO:0042692; GO:0042802; GO:0042803; GO:0045211; GO:0051015; GO:0051642; GO:0090292; GO:0140444; GO:1902017 44871 XM_044327778.1 2836 1564 1586 3570 3522 Q6ZWR6 9.03e-38 Nesprin-1 (Enaptin) (KASH domain-containing protein 1) (KASH1) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) Mus musculus (Mouse) centrosome localization [GO:0051642]; Golgi organization [GO:0007030]; muscle cell differentiation [GO:0042692]; nuclear matrix anchoring at nuclear membrane [GO:0090292]; nuclear migration [GO:0007097]; regulation of cilium assembly [GO:1902017]; spermatogenesis [GO:0007283] GO:0000932; GO:0003779; GO:0005521; GO:0005635; GO:0005640; GO:0005654; GO:0005730; GO:0005737; GO:0005794; GO:0005856; GO:0007030; GO:0007097; GO:0007283; GO:0016020; GO:0019899; GO:0030017; GO:0031965; GO:0034993; GO:0042692; GO:0042802; GO:0042803; GO:0045211; GO:0051015; GO:0051642; GO:0090292; GO:0140444; GO:1902017 44872 XM_044311541.1 4 21 3 11 0 Q96MB7 4.49e-38 Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease) Homo sapiens (Human) NA GO:0004518; GO:0005634; GO:0005829; GO:0005886; GO:0034451; GO:0046872 44873 XM_044309426.1 16 38 11 98 21 NA NA NA NA NA NA 44874 XM_029329292.2 4260 2699 2548 2590 2961 Q4V920 1.06e-94 Protein kinase C and casein kinase substrate in neurons protein 1 (Syndapin-1) Danio rerio (Zebrafish) (Brachydanio rerio) actin filament organization [GO:0007015]; auditory receptor cell stereocilium organization [GO:0060088]; cilium assembly [GO:0060271]; cytoskeleton organization [GO:0007010]; endocytosis [GO:0006897]; neuron projection morphogenesis [GO:0048812]; plasma membrane tubulation [GO:0097320]; positive regulation of dendrite development [GO:1900006]; regulation of endocytosis [GO:0030100] GO:0005543; GO:0005737; GO:0005768; GO:0005829; GO:0005886; GO:0006897; GO:0007010; GO:0007015; GO:0030100; GO:0030659; GO:0032587; GO:0043005; GO:0045202; GO:0048812; GO:0060088; GO:0060271; GO:0097320; GO:1900006 44875 XM_044308943.1 8 4 3 15 1 NA NA NA NA NA NA 44876 XR_006395288.1 149 272 141 142 108 P48416 2.85e-83 Cytochrome P450 10 (EC 1.14.-.-) (CYPX) Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004497; GO:0005506; GO:0016705; GO:0020037 44877 XM_029341831.2 315 341 186 506 465 NA NA NA NA NA NA 44878 XM_029338402.2 1300 1101 481 1120 1678 Q96NN9 5.27e-163 Apoptosis-inducing factor 3 (EC 1.-.-.-) (Apoptosis-inducing factor-like protein) Homo sapiens (Human) execution phase of apoptosis [GO:0097194] GO:0005737; GO:0005739; GO:0005743; GO:0005783; GO:0005829; GO:0016651; GO:0046872; GO:0050660; GO:0051537; GO:0097194 44879 XM_029338130.2 0 22 13 0 6 P08510 1.49e-86 Potassium voltage-gated channel protein Shaker (Protein minisleep) Drosophila melanogaster (Fruit fly) action potential [GO:0001508]; axon extension [GO:0048675]; behavioral response to ether [GO:0048150]; cellular response to dopamine [GO:1903351]; courtship behavior [GO:0007619]; detection of visible light [GO:0009584]; larval locomotory behavior [GO:0008345]; learning or memory [GO:0007611]; mating behavior, sex discrimination [GO:0048047]; positive regulation of circadian sleep/wake cycle, sleep [GO:0045938]; positive regulation of membrane potential [GO:0045838]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; proboscis extension reflex [GO:0007637]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; regulation of ion transmembrane transport [GO:0034765]; regulation of synaptic activity [GO:0060025]; sensory perception of taste [GO:0050909]; sleep [GO:0030431] GO:0001508; GO:0005249; GO:0005251; GO:0006813; GO:0007611; GO:0007619; GO:0007637; GO:0008076; GO:0008345; GO:0009584; GO:0016020; GO:0022843; GO:0030431; GO:0034765; GO:0045187; GO:0045838; GO:0045938; GO:0048047; GO:0048150; GO:0048675; GO:0050909; GO:0051260; GO:0060025; GO:0071805; GO:1903351 44880 XM_044324335.1 0 113 37 103 113 G8HTB6 6.86e-44 ZP domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 44881 XM_044306890.1 92 34 83 74 158 Q7TN88 4.8e-67 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 44882 XM_044306890.1 92 34 83 74 158 Q7TN88 1.61e-43 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 44883 XM_029323544.2 218 187 284 290 274 A1VBA6 7.02e-23 FMN-dependent NADH:quinone oxidoreductase (EC 1.6.5.-) (Azo-dye reductase) (FMN-dependent NADH-azo compound oxidoreductase) (FMN-dependent NADH-azoreductase) (EC 1.7.1.17) Desulfovibrio vulgaris subsp. vulgaris (strain DP4) NA GO:0009055; GO:0010181; GO:0016652; GO:0016655 44884 XM_029339732.2 159 33 62 49 78 Q6GLQ4 1.25e-25 Serine/threonine-protein phosphatase 1 regulatory subunit 10 Xenopus laevis (African clawed frog) NA GO:0004864; GO:0005634; GO:0046872 44885 XM_029339732.2 159 33 62 49 78 Q6GLQ4 2.75e-25 Serine/threonine-protein phosphatase 1 regulatory subunit 10 Xenopus laevis (African clawed frog) NA GO:0004864; GO:0005634; GO:0046872 44886 XM_029341246.2 182 572 271 171 193 NA NA NA NA NA NA 44887 XM_044314072.1 1976 1819 1067 2023 2219 O94876 2.72e-35 Transmembrane and coiled-coil domains protein 1 Homo sapiens (Human) endoplasmic reticulum organization [GO:0007029]; endosomal transport [GO:0016197]; endosome fission [GO:0140285]; endosome membrane tubulation [GO:0097750]; membrane fission [GO:0090148] GO:0005789; GO:0005791; GO:0005829; GO:0007029; GO:0012505; GO:0016197; GO:0042802; GO:0090148; GO:0097750; GO:0140284; GO:0140285 44888 XR_006397431.1 0 3 12 2 13 NA NA NA NA NA NA 44889 XM_029333401.2 405 210 148 452 593 Q5SPP5 0 Protein EFR3 homolog B Danio rerio (Zebrafish) (Brachydanio rerio) phosphatidylinositol phosphate biosynthetic process [GO:0046854]; protein localization to plasma membrane [GO:0072659] GO:0005886; GO:0046854; GO:0072659 44890 XM_044311171.1 139 0 0 19 0 NA NA NA NA NA NA 44891 XM_029354486.2 10 48 14 95 286 NA NA NA NA NA NA 44892 XM_044325997.1 523 313 470 518 650 Q13535 0 Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein) (FRAP-related protein 1) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; cellular response to UV [GO:0034644]; DNA damage checkpoint signaling [GO:0000077]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; establishment of protein-containing complex localization to telomere [GO:0097695]; establishment of RNA localization to telomere [GO:0097694]; interstrand cross-link repair [GO:0036297]; negative regulation of DNA replication [GO:0008156]; nucleobase-containing compound metabolic process [GO:0006139]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043517]; positive regulation of telomerase catalytic core complex assembly [GO:1904884]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein autophosphorylation [GO:0046777]; protein localization to chromosome, telomeric region [GO:0070198]; protein phosphorylation [GO:0006468]; regulation of cellular response to heat [GO:1900034]; regulation of double-strand break repair [GO:2000779]; replication fork processing [GO:0031297]; replicative senescence [GO:0090399]; response to arsenic-containing substance [GO:0046685]; response to xenobiotic stimulus [GO:0009410]; telomere maintenance [GO:0000723] GO:0000077; GO:0000723; GO:0003677; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005694; GO:0005794; GO:0006139; GO:0006260; GO:0006281; GO:0006468; GO:0006974; GO:0008156; GO:0009410; GO:0016605; GO:0018105; GO:0031297; GO:0032212; GO:0032405; GO:0032407; GO:0034644; GO:0036297; GO:0043517; GO:0046685; GO:0046777; GO:0070198; GO:0070310; GO:0071480; GO:0090399; GO:0097694; GO:0097695; GO:0106310; GO:1900034; GO:1904884; GO:2000779 44893 XM_044324428.1 9 2 27 0 0 NA NA NA NA NA NA 44894 XM_044323563.1 0 0 0 4 20 NA NA NA NA NA NA 44895 XM_029342700.2 116 82 1 82 61 Q969U6 1.29e-36 F-box/WD repeat-containing protein 5 (F-box and WD-40 domain-containing protein 5) Homo sapiens (Human) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of centrosome duplication [GO:0010824]; regulation of mitotic nuclear division [GO:0007088]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0005737; GO:0005829; GO:0007088; GO:0010824; GO:0016567; GO:0019005; GO:0019901; GO:0031146; GO:0043161; GO:0080008 44896 XM_029342700.2 116 82 1 82 61 Q969U6 2e-33 F-box/WD repeat-containing protein 5 (F-box and WD-40 domain-containing protein 5) Homo sapiens (Human) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of centrosome duplication [GO:0010824]; regulation of mitotic nuclear division [GO:0007088]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0005737; GO:0005829; GO:0007088; GO:0010824; GO:0016567; GO:0019005; GO:0019901; GO:0031146; GO:0043161; GO:0080008 44897 XM_044310313.1 9 11 17 58 5 P04323 1.02e-64 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 44898 XM_044310313.1 9 11 17 58 5 P04323 1.02e-64 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 44899 XM_044307214.1 1579 1270 30 359 666 NA NA NA NA NA NA 44900 XM_029354330.2 20 15 2 12 9 NA NA NA NA NA NA 44901 XM_029354192.2 203 107 87 128 122 NA NA NA NA NA NA 44902 XM_044323118.1 5 1 2 16 8 Q8BHB0 1.28e-24 Nucleotide-binding oligomerization domain-containing protein 1 (Caspase recruitment domain-containing protein 4) Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cellular response to muramyl dipeptide [GO:0071225]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; ERK1 and ERK2 cascade [GO:0070371]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of cell death [GO:0010942]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of xenophagy [GO:1904417]; regulation of apoptotic process [GO:0042981]; stress-activated MAPK cascade [GO:0051403]; xenophagy [GO:0098792] GO:0002221; GO:0002606; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006915; GO:0006919; GO:0007249; GO:0007254; GO:0010942; GO:0016045; GO:0016323; GO:0016324; GO:0032731; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0035556; GO:0038187; GO:0042742; GO:0042802; GO:0042803; GO:0042981; GO:0043123; GO:0043280; GO:0044877; GO:0045087; GO:0045335; GO:0046330; GO:0050700; GO:0050830; GO:0051000; GO:0051092; GO:0051403; GO:0060907; GO:0070371; GO:0070374; GO:0071225; GO:0098792; GO:1901224; GO:1904417 44903 XM_029332910.2 121 104 36 126 47 NA NA NA NA NA NA 44904 XM_029346061.2 39 25 10 0 18 Q8CFK2 2.27e-115 Transcription factor IIIB 90 kDa subunit (TFIIIB90) (mTFIIIB90) (B-related factor 1) (BRF-1) Mus musculus (Mouse) DNA-templated transcription initiation [GO:0006352]; positive regulation of transcription by RNA polymerase III [GO:0045945]; regulation of mRNA stability [GO:0043488]; transcription by RNA polymerase III [GO:0006383]; transcription preinitiation complex assembly [GO:0070897] GO:0000126; GO:0000995; GO:0001006; GO:0005634; GO:0006352; GO:0006383; GO:0017025; GO:0043488; GO:0045945; GO:0046872; GO:0070897; GO:0097550 44905 XM_044323914.1 0 22 58 314 139 P07911 3.24e-47 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Homo sapiens (Human) antibacterial innate immune response [GO:0140367]; apoptotic signaling pathway [GO:0097190]; autophagy [GO:0006914]; cellular calcium ion homeostasis [GO:0006874]; cellular chloride ion homeostasis [GO:0030644]; cellular defense response [GO:0006968]; cellular phosphate ion homeostasis [GO:0030643]; cellular response to unfolded protein [GO:0034620]; cellular sodium ion homeostasis [GO:0006883]; chaperone-mediated protein folding [GO:0061077]; citric acid secretion [GO:0046720]; collecting duct development [GO:0072044]; connective tissue replacement [GO:0097709]; creatinine homeostasis [GO:0097273]; defense response to Gram-negative bacterium [GO:0050829]; endoplasmic reticulum organization [GO:0007029]; glomerular filtration [GO:0003094]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; juxtaglomerular apparatus development [GO:0072051]; leukocyte cell-cell adhesion [GO:0007159]; lipid metabolic process [GO:0006629]; metanephric ascending thin limb development [GO:0072218]; metanephric distal convoluted tubule development [GO:0072221]; metanephric thick ascending limb development [GO:0072233]; micturition [GO:0060073]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell population proliferation [GO:0008285]; neutrophil migration [GO:1990266]; organ or tissue specific immune response [GO:0002251]; peptidyl-threonine phosphorylation [GO:0018107]; potassium ion homeostasis [GO:0055075]; protein localization to vacuole [GO:0072665]; protein transport into plasma membrane raft [GO:0044861]; regulation of blood pressure [GO:0008217]; regulation of protein transport [GO:0051223]; regulation of urine volume [GO:0035809]; renal sodium ion absorption [GO:0070294]; renal urate salt excretion [GO:0097744]; renal water homeostasis [GO:0003091]; response to lipopolysaccharide [GO:0032496]; response to water deprivation [GO:0009414]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; ubiquitin-dependent ERAD pathway [GO:0030433]; urate transport [GO:0015747]; urea transmembrane transport [GO:0071918] GO:0000922; GO:0002251; GO:0003091; GO:0003094; GO:0005201; GO:0005509; GO:0005615; GO:0005783; GO:0005796; GO:0005929; GO:0006629; GO:0006874; GO:0006883; GO:0006914; GO:0006954; GO:0006968; GO:0007029; GO:0007157; GO:0007159; GO:0008217; GO:0008285; GO:0008380; GO:0009410; GO:0009414; GO:0009986; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0018107; GO:0019864; GO:0019898; GO:0030433; GO:0030643; GO:0030644; GO:0032496; GO:0033209; GO:0033555; GO:0034620; GO:0035809; GO:0044861; GO:0046720; GO:0050829; GO:0051223; GO:0055075; GO:0060073; GO:0060170; GO:0061077; GO:0070062; GO:0070294; GO:0071918; GO:0072044; GO:0072051; GO:0072218; GO:0072221; GO:0072233; GO:0072665; GO:0097190; GO:0097273; GO:0097709; GO:0097744; GO:0140367; GO:1990266 44906 XM_044311147.1 12 20 29 14 67 A0A1B0GUU1 6.25e-58 Uncharacterized protein C17orf113 Homo sapiens (Human) NA NA 44907 XM_044327971.1 5 6 5 9 43 NA NA NA NA NA NA 44908 XM_029325369.2 0 14 0 1 0 P48040 1.54e-21 Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor) Ovis aries (Sheep) NA GO:0005886; GO:0008502 44909 XM_044310883.1 4 1 0 8 0 Q96DM1 3.19e-54 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 44910 XM_029330197.2 36 26 0 46 42 Q40784 2.07e-53 Putative glucose-6-phosphate 1-epimerase (EC 5.1.3.15) (Putative D-hexose-6-phosphate mutarotase) (Putative apospory-associated protein C) Cenchrus ciliaris (Buffelgrass) (Pennisetum ciliare) carbohydrate metabolic process [GO:0005975] GO:0005975; GO:0030246; GO:0047938 44911 XM_044317315.1 0 0 3 16 0 NA NA NA NA NA NA 44912 XR_006396393.1 26 0 22 10 37 NA NA NA NA NA NA 44913 XM_029326179.2 336 354 234 406 484 P08836 1.04e-121 Farnesyl pyrophosphate synthase (FPP synthase) (FPS) (EC 2.5.1.10) ((2E,6E)-farnesyl diphosphate synthase) (Dimethylallyltranstransferase) (EC 2.5.1.1) (Farnesyl diphosphate synthase) (Geranyltranstransferase) Gallus gallus (Chicken) cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384] GO:0004161; GO:0004337; GO:0005737; GO:0006695; GO:0033384; GO:0045337; GO:0046872 44914 XM_029337699.2 124 35 67 68 170 Q5RKI3 5.17e-146 DNA polymerase lambda (Pol Lambda) (EC 2.7.7.7) (EC 4.2.99.-) Rattus norvegicus (Rat) base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289] GO:0000724; GO:0003677; GO:0003887; GO:0005634; GO:0005654; GO:0006260; GO:0006287; GO:0006289; GO:0006303; GO:0035861; GO:0046872; GO:0051575; GO:0071897 44915 XR_006396795.1 137 27 16 51 79 NA NA NA NA NA NA 44916 XM_044324566.1 17 0 19 16 41 NA NA NA NA NA NA 44917 XM_044307764.1 61 35 48 9 56 P18074 0 General transcription and DNA repair factor IIH helicase subunit XPD (TFIIH subunit XPD) (EC 3.6.4.12) (Basic transcription factor 2 80 kDa subunit) (BTF2 p80) (CXPD) (DNA excision repair protein ERCC-2) (DNA repair protein complementing XP-D cells) (TFIIH basal transcription factor complex 80 kDa subunit) (TFIIH 80 kDa subunit) (TFIIH p80) (Xeroderma pigmentosum group D-complementing protein) Homo sapiens (Human) aging [GO:0007568]; apoptotic process [GO:0006915]; bone mineralization [GO:0030282]; central nervous system myelin formation [GO:0032289]; chromosome segregation [GO:0007059]; embryonic cleavage [GO:0040016]; erythrocyte maturation [GO:0043249]; extracellular matrix organization [GO:0030198]; hair cell differentiation [GO:0035315]; hair follicle maturation [GO:0048820]; hematopoietic stem cell differentiation [GO:0060218]; hematopoietic stem cell proliferation [GO:0071425]; in utero embryonic development [GO:0001701]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; multicellular organism growth [GO:0035264]; nucleotide-excision repair [GO:0006289]; positive regulation of DNA binding [GO:0043388]; positive regulation of mitotic recombination [GO:0045951]; post-embryonic development [GO:0009791]; regulation of mitotic cell cycle phase transition [GO:1901990]; response to oxidative stress [GO:0006979]; spinal cord development [GO:0021510]; transcription by RNA polymerase II [GO:0006366]; transcription elongation by RNA polymerase I [GO:0006362]; transcription-coupled nucleotide-excision repair [GO:0006283]; UV protection [GO:0009650] GO:0000439; GO:0000462; GO:0001701; GO:0003678; GO:0003684; GO:0005524; GO:0005634; GO:0005654; GO:0005669; GO:0005675; GO:0005737; GO:0005819; GO:0005829; GO:0006283; GO:0006289; GO:0006362; GO:0006366; GO:0006915; GO:0006979; GO:0007059; GO:0007568; GO:0008022; GO:0009650; GO:0009791; GO:0016887; GO:0021510; GO:0030198; GO:0030282; GO:0030674; GO:0032289; GO:0035264; GO:0035315; GO:0040016; GO:0043139; GO:0043249; GO:0043388; GO:0045951; GO:0046872; GO:0047485; GO:0048820; GO:0051539; GO:0060218; GO:0070516; GO:0071425; GO:0071817; GO:1901990 44918 XM_029346186.2 294 304 234 320 364 P09481 4.13e-101 Neuronal acetylcholine receptor subunit alpha-3 Gallus gallus (Chicken) behavioral response to nicotine [GO:0035095]; chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system development [GO:0007399]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165]; synaptic transmission involved in micturition [GO:0060084] GO:0005231; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0007399; GO:0015464; GO:0016607; GO:0022848; GO:0030594; GO:0034220; GO:0035095; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051899; GO:0060084; GO:1904315 44919 XR_006392468.1 30 0 28 197 135 NA NA NA NA NA NA 44920 XR_006393592.1 15 24 24 59 14 A2AJ76 8.11e-50 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 44921 XR_006393592.1 15 24 24 59 14 A2AJ76 4.89e-45 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 44922 XR_006393592.1 15 24 24 59 14 A2AJ76 1.23e-39 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 44923 XR_006393592.1 15 24 24 59 14 A2AJ76 5.33e-39 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 44924 XR_006393592.1 15 24 24 59 14 A2AJ76 5.09e-37 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 44925 XR_006393592.1 15 24 24 59 14 A2AJ76 1.21e-29 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 44926 XR_006393592.1 15 24 24 59 14 A2AJ76 6.83e-26 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 44927 XM_044313194.1 1 0 6 0 8 NA NA NA NA NA NA 44928 XM_044306987.1 284 413 116 370 90 Q91XE9 5e-40 Cyclic AMP-responsive element-binding protein 3-like protein 3 (cAMP-responsive element-binding protein 3-like protein 3) (Transcription factor CREB-H) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3-like protein 3] Mus musculus (Mouse) positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; regulation of transcription by RNA polymerase II [GO:0006357]; response to unfolded protein [GO:0006986] GO:0000976; GO:0000977; GO:0000978; GO:0000981; GO:0001228; GO:0005634; GO:0005654; GO:0005783; GO:0005789; GO:0005829; GO:0006357; GO:0006986; GO:0016020; GO:0042802; GO:0042803; GO:0045944; GO:0046982; GO:1990440 44929 XM_044315063.1 21 24 16 0 14 NA NA NA NA NA NA 44930 XM_044314886.1 134 0 63 192 142 Q9JHX4 3.47e-29 Caspase-8 (CASP-8) (EC 3.4.22.61) [Cleaved into: Caspase-8 subunit p18; Caspase-8 subunit p10] Rattus norvegicus (Rat) activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; execution phase of apoptosis [GO:0097194]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; heart development [GO:0007507]; hepatocyte apoptotic process [GO:0097284]; macrophage differentiation [GO:0030225]; necroptotic process [GO:0070266]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of necroptotic process [GO:0060546]; neural tube formation [GO:0001841]; positive regulation of apoptotic process [GO:0043065]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of neuron death [GO:1901216]; positive regulation of proteolysis [GO:0045862]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; pyroptosis [GO:0070269]; regulation of apoptotic signaling pathway [GO:2001233]; regulation of cytokine production [GO:0001817]; regulation of innate immune response [GO:0045088]; regulation of thymocyte apoptotic process [GO:0070243]; response to antibiotic [GO:0046677]; response to cobalt ion [GO:0032025]; response to cold [GO:0009409]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]; self proteolysis [GO:0097264]; TRAIL-activated apoptotic signaling pathway [GO:0036462] GO:0001525; GO:0001817; GO:0001841; GO:0004175; GO:0004197; GO:0005123; GO:0005164; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0006508; GO:0006915; GO:0006919; GO:0007507; GO:0008233; GO:0008303; GO:0008625; GO:0009409; GO:0016485; GO:0030225; GO:0030690; GO:0031264; GO:0031265; GO:0031625; GO:0032025; GO:0032355; GO:0032496; GO:0032731; GO:0032991; GO:0034612; GO:0035877; GO:0036462; GO:0042802; GO:0043005; GO:0043065; GO:0043123; GO:0043124; GO:0044297; GO:0044877; GO:0045088; GO:0045121; GO:0045471; GO:0045651; GO:0045862; GO:0046677; GO:0051603; GO:0060546; GO:0070243; GO:0070266; GO:0070269; GO:0071260; GO:0071407; GO:0097110; GO:0097153; GO:0097190; GO:0097191; GO:0097194; GO:0097199; GO:0097200; GO:0097202; GO:0097264; GO:0097284; GO:0097342; GO:1901216; GO:2001233; GO:2001238 44931 XM_029352980.2 0 129 0 0 0 P35295 1.17e-38 Ras-related protein Rab-20 Mus musculus (Mouse) cellular response to type II interferon [GO:0071346]; intracellular protein transport [GO:0006886]; phagosome acidification [GO:0090383]; phagosome-lysosome fusion [GO:0090385] GO:0003924; GO:0005525; GO:0005794; GO:0006886; GO:0012505; GO:0030670; GO:0043231; GO:0045335; GO:0071346; GO:0090383; GO:0090385 44932 XM_029325704.2 53 1 20 16 86 NA NA NA NA NA NA 44933 XM_044327400.1 160 149 315 544 216 NA NA NA NA NA NA 44934 XM_044315194.1 66 22 4 72 3 NA NA NA NA NA NA 44935 XR_006392663.1 30 9 4 20 1 Q96AY4 4.99e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44936 XR_006392663.1 30 9 4 20 1 Q96AY4 9.09e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44937 XR_006392663.1 30 9 4 20 1 Q96AY4 3.14e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44938 XR_006392663.1 30 9 4 20 1 Q96AY4 3.81e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44939 XR_006392663.1 30 9 4 20 1 Q96AY4 3.81e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44940 XR_006392663.1 30 9 4 20 1 Q96AY4 1.17e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44941 XR_006392663.1 30 9 4 20 1 Q96AY4 2.85e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44942 XR_006392663.1 30 9 4 20 1 Q96AY4 2.14e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44943 XR_006392663.1 30 9 4 20 1 Q96AY4 3.41e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44944 XR_006392663.1 30 9 4 20 1 Q96AY4 2.4e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44945 XR_006392663.1 30 9 4 20 1 Q96AY4 1.29e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 44946 XM_029343188.2 1711 1128 875 1657 1351 Q96JQ0 1.48e-81 Protocadherin-16 (Cadherin-19) (Cadherin-25) (Fibroblast cadherin-1) (Protein dachsous homolog 1) Homo sapiens (Human) adherens junction organization [GO:0034332]; branching involved in ureteric bud morphogenesis [GO:0001658]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell migration involved in endocardial cushion formation [GO:0003273]; cell morphogenesis [GO:0000902]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; cell-cell junction assembly [GO:0007043]; cochlea development [GO:0090102]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; mitral valve formation [GO:0003192]; neural tube development [GO:0021915]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; pattern specification process [GO:0007389]; post-anal tail morphogenesis [GO:0036342]; protein localization to plasma membrane [GO:0072659] GO:0000902; GO:0001658; GO:0003192; GO:0003273; GO:0005509; GO:0005912; GO:0007043; GO:0007156; GO:0007157; GO:0007389; GO:0016020; GO:0016339; GO:0016342; GO:0021915; GO:0022008; GO:0034332; GO:0035329; GO:0036342; GO:0043931; GO:0045177; GO:0045296; GO:0048565; GO:0072137; GO:0072659; GO:0090102; GO:0098742 44947 XM_029343188.2 1711 1128 875 1657 1351 Q96JQ0 1.87e-49 Protocadherin-16 (Cadherin-19) (Cadherin-25) (Fibroblast cadherin-1) (Protein dachsous homolog 1) Homo sapiens (Human) adherens junction organization [GO:0034332]; branching involved in ureteric bud morphogenesis [GO:0001658]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell migration involved in endocardial cushion formation [GO:0003273]; cell morphogenesis [GO:0000902]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; cell-cell junction assembly [GO:0007043]; cochlea development [GO:0090102]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; mitral valve formation [GO:0003192]; neural tube development [GO:0021915]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; pattern specification process [GO:0007389]; post-anal tail morphogenesis [GO:0036342]; protein localization to plasma membrane [GO:0072659] GO:0000902; GO:0001658; GO:0003192; GO:0003273; GO:0005509; GO:0005912; GO:0007043; GO:0007156; GO:0007157; GO:0007389; GO:0016020; GO:0016339; GO:0016342; GO:0021915; GO:0022008; GO:0034332; GO:0035329; GO:0036342; GO:0043931; GO:0045177; GO:0045296; GO:0048565; GO:0072137; GO:0072659; GO:0090102; GO:0098742 44948 XM_029343188.2 1711 1128 875 1657 1351 Q96JQ0 9.67e-41 Protocadherin-16 (Cadherin-19) (Cadherin-25) (Fibroblast cadherin-1) (Protein dachsous homolog 1) Homo sapiens (Human) adherens junction organization [GO:0034332]; branching involved in ureteric bud morphogenesis [GO:0001658]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell migration involved in endocardial cushion formation [GO:0003273]; cell morphogenesis [GO:0000902]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; cell-cell junction assembly [GO:0007043]; cochlea development [GO:0090102]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; mitral valve formation [GO:0003192]; neural tube development [GO:0021915]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; pattern specification process [GO:0007389]; post-anal tail morphogenesis [GO:0036342]; protein localization to plasma membrane [GO:0072659] GO:0000902; GO:0001658; GO:0003192; GO:0003273; GO:0005509; GO:0005912; GO:0007043; GO:0007156; GO:0007157; GO:0007389; GO:0016020; GO:0016339; GO:0016342; GO:0021915; GO:0022008; GO:0034332; GO:0035329; GO:0036342; GO:0043931; GO:0045177; GO:0045296; GO:0048565; GO:0072137; GO:0072659; GO:0090102; GO:0098742 44949 XM_029343188.2 1711 1128 875 1657 1351 Q96JQ0 8.06e-40 Protocadherin-16 (Cadherin-19) (Cadherin-25) (Fibroblast cadherin-1) (Protein dachsous homolog 1) Homo sapiens (Human) adherens junction organization [GO:0034332]; branching involved in ureteric bud morphogenesis [GO:0001658]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell migration involved in endocardial cushion formation [GO:0003273]; cell morphogenesis [GO:0000902]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; cell-cell junction assembly [GO:0007043]; cochlea development [GO:0090102]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; mitral valve formation [GO:0003192]; neural tube development [GO:0021915]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; pattern specification process [GO:0007389]; post-anal tail morphogenesis [GO:0036342]; protein localization to plasma membrane [GO:0072659] GO:0000902; GO:0001658; GO:0003192; GO:0003273; GO:0005509; GO:0005912; GO:0007043; GO:0007156; GO:0007157; GO:0007389; GO:0016020; GO:0016339; GO:0016342; GO:0021915; GO:0022008; GO:0034332; GO:0035329; GO:0036342; GO:0043931; GO:0045177; GO:0045296; GO:0048565; GO:0072137; GO:0072659; GO:0090102; GO:0098742 44950 XM_029343188.2 1711 1128 875 1657 1351 Q96JQ0 3.86e-38 Protocadherin-16 (Cadherin-19) (Cadherin-25) (Fibroblast cadherin-1) (Protein dachsous homolog 1) Homo sapiens (Human) adherens junction organization [GO:0034332]; branching involved in ureteric bud morphogenesis [GO:0001658]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell migration involved in endocardial cushion formation [GO:0003273]; cell morphogenesis [GO:0000902]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; cell-cell junction assembly [GO:0007043]; cochlea development [GO:0090102]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; mitral valve formation [GO:0003192]; neural tube development [GO:0021915]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; pattern specification process [GO:0007389]; post-anal tail morphogenesis [GO:0036342]; protein localization to plasma membrane [GO:0072659] GO:0000902; GO:0001658; GO:0003192; GO:0003273; GO:0005509; GO:0005912; GO:0007043; GO:0007156; GO:0007157; GO:0007389; GO:0016020; GO:0016339; GO:0016342; GO:0021915; GO:0022008; GO:0034332; GO:0035329; GO:0036342; GO:0043931; GO:0045177; GO:0045296; GO:0048565; GO:0072137; GO:0072659; GO:0090102; GO:0098742 44951 XM_029343188.2 1711 1128 875 1657 1351 Q96JQ0 4.53e-35 Protocadherin-16 (Cadherin-19) (Cadherin-25) (Fibroblast cadherin-1) (Protein dachsous homolog 1) Homo sapiens (Human) adherens junction organization [GO:0034332]; branching involved in ureteric bud morphogenesis [GO:0001658]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell migration involved in endocardial cushion formation [GO:0003273]; cell morphogenesis [GO:0000902]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; cell-cell junction assembly [GO:0007043]; cochlea development [GO:0090102]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; mitral valve formation [GO:0003192]; neural tube development [GO:0021915]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; pattern specification process [GO:0007389]; post-anal tail morphogenesis [GO:0036342]; protein localization to plasma membrane [GO:0072659] GO:0000902; GO:0001658; GO:0003192; GO:0003273; GO:0005509; GO:0005912; GO:0007043; GO:0007156; GO:0007157; GO:0007389; GO:0016020; GO:0016339; GO:0016342; GO:0021915; GO:0022008; GO:0034332; GO:0035329; GO:0036342; GO:0043931; GO:0045177; GO:0045296; GO:0048565; GO:0072137; GO:0072659; GO:0090102; GO:0098742 44952 XM_029343188.2 1711 1128 875 1657 1351 Q96JQ0 9.53e-35 Protocadherin-16 (Cadherin-19) (Cadherin-25) (Fibroblast cadherin-1) (Protein dachsous homolog 1) Homo sapiens (Human) adherens junction organization [GO:0034332]; branching involved in ureteric bud morphogenesis [GO:0001658]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell migration involved in endocardial cushion formation [GO:0003273]; cell morphogenesis [GO:0000902]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; cell-cell junction assembly [GO:0007043]; cochlea development [GO:0090102]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; mitral valve formation [GO:0003192]; neural tube development [GO:0021915]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; pattern specification process [GO:0007389]; post-anal tail morphogenesis [GO:0036342]; protein localization to plasma membrane [GO:0072659] GO:0000902; GO:0001658; GO:0003192; GO:0003273; GO:0005509; GO:0005912; GO:0007043; GO:0007156; GO:0007157; GO:0007389; GO:0016020; GO:0016339; GO:0016342; GO:0021915; GO:0022008; GO:0034332; GO:0035329; GO:0036342; GO:0043931; GO:0045177; GO:0045296; GO:0048565; GO:0072137; GO:0072659; GO:0090102; GO:0098742 44953 XM_029343188.2 1711 1128 875 1657 1351 Q96JQ0 3.94e-33 Protocadherin-16 (Cadherin-19) (Cadherin-25) (Fibroblast cadherin-1) (Protein dachsous homolog 1) Homo sapiens (Human) adherens junction organization [GO:0034332]; branching involved in ureteric bud morphogenesis [GO:0001658]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell migration involved in endocardial cushion formation [GO:0003273]; cell morphogenesis [GO:0000902]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; cell-cell junction assembly [GO:0007043]; cochlea development [GO:0090102]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; mitral valve formation [GO:0003192]; neural tube development [GO:0021915]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; pattern specification process [GO:0007389]; post-anal tail morphogenesis [GO:0036342]; protein localization to plasma membrane [GO:0072659] GO:0000902; GO:0001658; GO:0003192; GO:0003273; GO:0005509; GO:0005912; GO:0007043; GO:0007156; GO:0007157; GO:0007389; GO:0016020; GO:0016339; GO:0016342; GO:0021915; GO:0022008; GO:0034332; GO:0035329; GO:0036342; GO:0043931; GO:0045177; GO:0045296; GO:0048565; GO:0072137; GO:0072659; GO:0090102; GO:0098742 44954 XM_029343188.2 1711 1128 875 1657 1351 Q96JQ0 1.67e-31 Protocadherin-16 (Cadherin-19) (Cadherin-25) (Fibroblast cadherin-1) (Protein dachsous homolog 1) Homo sapiens (Human) adherens junction organization [GO:0034332]; branching involved in ureteric bud morphogenesis [GO:0001658]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell migration involved in endocardial cushion formation [GO:0003273]; cell morphogenesis [GO:0000902]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; cell-cell junction assembly [GO:0007043]; cochlea development [GO:0090102]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; mitral valve formation [GO:0003192]; neural tube development [GO:0021915]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; pattern specification process [GO:0007389]; post-anal tail morphogenesis [GO:0036342]; protein localization to plasma membrane [GO:0072659] GO:0000902; GO:0001658; GO:0003192; GO:0003273; GO:0005509; GO:0005912; GO:0007043; GO:0007156; GO:0007157; GO:0007389; GO:0016020; GO:0016339; GO:0016342; GO:0021915; GO:0022008; GO:0034332; GO:0035329; GO:0036342; GO:0043931; GO:0045177; GO:0045296; GO:0048565; GO:0072137; GO:0072659; GO:0090102; GO:0098742 44955 XM_029343188.2 1711 1128 875 1657 1351 Q96JQ0 8.66e-25 Protocadherin-16 (Cadherin-19) (Cadherin-25) (Fibroblast cadherin-1) (Protein dachsous homolog 1) Homo sapiens (Human) adherens junction organization [GO:0034332]; branching involved in ureteric bud morphogenesis [GO:0001658]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell migration involved in endocardial cushion formation [GO:0003273]; cell morphogenesis [GO:0000902]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; cell-cell junction assembly [GO:0007043]; cochlea development [GO:0090102]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; mitral valve formation [GO:0003192]; neural tube development [GO:0021915]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; pattern specification process [GO:0007389]; post-anal tail morphogenesis [GO:0036342]; protein localization to plasma membrane [GO:0072659] GO:0000902; GO:0001658; GO:0003192; GO:0003273; GO:0005509; GO:0005912; GO:0007043; GO:0007156; GO:0007157; GO:0007389; GO:0016020; GO:0016339; GO:0016342; GO:0021915; GO:0022008; GO:0034332; GO:0035329; GO:0036342; GO:0043931; GO:0045177; GO:0045296; GO:0048565; GO:0072137; GO:0072659; GO:0090102; GO:0098742 44956 XM_044307609.1 2263 732 215 452 497 E0W1I1 3.03e-74 Serine/threonine-protein kinase Pink1, mitochondrial (EC 2.7.11.1) (PTEN-induced putative kinase 1) Pediculus humanus subsp. corporis (Body louse) autophagy [GO:0006914]; protein phosphorylation [GO:0006468] GO:0004672; GO:0004674; GO:0005524; GO:0005741; GO:0005743; GO:0005829; GO:0006468; GO:0006914; GO:0046872 44957 XM_029340119.2 175 246 99 204 120 NA NA NA NA NA NA 44958 XM_044327120.1 333 122 268 302 188 Q9NXB0 6.95e-139 Tectonic-like complex member MKS1 (Meckel syndrome type 1 protein) Homo sapiens (Human) branching morphogenesis of an epithelial tube [GO:0048754]; cardiac septum morphogenesis [GO:0060411]; cilium assembly [GO:0060271]; common bile duct development [GO:0061009]; determination of left/right symmetry [GO:0007368]; embryonic brain development [GO:1990403]; embryonic digit morphogenesis [GO:0042733]; embryonic skeletal system development [GO:0048706]; epithelial structure maintenance [GO:0010669]; head development [GO:0060322]; inner ear receptor cell stereocilium organization [GO:0060122]; motile cilium assembly [GO:0044458]; neural tube closure [GO:0001843]; non-motile cilium assembly [GO:1905515]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:1901620]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation [GO:0003271] GO:0001843; GO:0003271; GO:0005737; GO:0005813; GO:0005814; GO:0005829; GO:0007368; GO:0010669; GO:0016020; GO:0036038; GO:0036064; GO:0042733; GO:0044458; GO:0048706; GO:0048754; GO:0060122; GO:0060271; GO:0060322; GO:0060411; GO:0060828; GO:0061009; GO:1901620; GO:1905515; GO:1990403; GO:2000095 44959 XM_044317504.1 11 9 12 13 12 B8VIU6 6.08e-38 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 44960 XM_044329243.1 35 0 177 118 343 P50748 0 Kinetochore-associated protein 1 (Rough deal homolog) (HsROD) (Rod) (hRod) Homo sapiens (Human) cell division [GO:0051301]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint signaling [GO:0007094]; protein localization to kinetochore involved in kinetochore assembly [GO:1903394]; protein-containing complex assembly [GO:0065003]; regulation of exit from mitosis [GO:0007096] GO:0000070; GO:0000922; GO:0005634; GO:0005737; GO:0005828; GO:0005829; GO:0005886; GO:0007094; GO:0007096; GO:0015629; GO:0031267; GO:0051301; GO:0065003; GO:1903394; GO:1990423 44961 XM_029324713.2 242 27 201 78 145 NA NA NA NA NA NA 44962 XM_044327565.1 0 0 0 2 10 NA NA NA NA NA NA 44963 XM_029333409.2 289 129 264 1030 807 Q5GH73 1.65e-23 XK-related protein 6 Homo sapiens (Human) apoptotic process involved in development [GO:1902742]; engulfment of apoptotic cell [GO:0043652]; phosphatidylserine exposure on apoptotic cell surface [GO:0070782] GO:0005886; GO:0016020; GO:0043652; GO:0070782; GO:1902742 44964 XM_044322644.1 34 34 30 50 51 NA NA NA NA NA NA 44965 XM_029333359.2 3 2 4 7 24 Q8N441 1.2e-29 Fibroblast growth factor receptor-like 1 (FGF receptor-like protein 1) (FGF homologous factor receptor) (FGFR-like protein) (Fibroblast growth factor receptor 5) (FGFR-5) Homo sapiens (Human) cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; diaphragm development [GO:0060539]; heart valve morphogenesis [GO:0003179]; negative regulation of cell population proliferation [GO:0008285]; skeletal system development [GO:0001501]; ventricular septum morphogenesis [GO:0060412] GO:0001501; GO:0003179; GO:0005007; GO:0005794; GO:0005886; GO:0008201; GO:0008285; GO:0017134; GO:0030133; GO:0042802; GO:0044291; GO:0060412; GO:0060539; GO:0098742 44966 XR_006396694.1 0 0 5 0 6 NA NA NA NA NA NA 44967 XR_006396510.1 0 4 8 0 170 NA NA NA NA NA NA 44968 XM_044328798.1 916 547 801 955 952 P09849 0 Lactase/phlorizin hydrolase (Lactase/glycosylceramidase) [Includes: Lactase (EC 3.2.1.108); Glycosylceramidase (EC 3.2.1.62) (Phlorizin hydrolase)] Oryctolagus cuniculus (Rabbit) cellobiose catabolic process [GO:2000892]; glycosylceramide catabolic process [GO:0046477]; lactose catabolic process [GO:0005990]; quercetin catabolic process [GO:1901733] GO:0000016; GO:0004336; GO:0004348; GO:0005990; GO:0008422; GO:0017042; GO:0042803; GO:0046477; GO:0080079; GO:0098591; GO:0140749; GO:1901733; GO:2000892 44969 XM_044328798.1 916 547 801 955 952 P09849 0 Lactase/phlorizin hydrolase (Lactase/glycosylceramidase) [Includes: Lactase (EC 3.2.1.108); Glycosylceramidase (EC 3.2.1.62) (Phlorizin hydrolase)] Oryctolagus cuniculus (Rabbit) cellobiose catabolic process [GO:2000892]; glycosylceramide catabolic process [GO:0046477]; lactose catabolic process [GO:0005990]; quercetin catabolic process [GO:1901733] GO:0000016; GO:0004336; GO:0004348; GO:0005990; GO:0008422; GO:0017042; GO:0042803; GO:0046477; GO:0080079; GO:0098591; GO:0140749; GO:1901733; GO:2000892 44970 XM_044328798.1 916 547 801 955 952 P09849 5.88e-117 Lactase/phlorizin hydrolase (Lactase/glycosylceramidase) [Includes: Lactase (EC 3.2.1.108); Glycosylceramidase (EC 3.2.1.62) (Phlorizin hydrolase)] Oryctolagus cuniculus (Rabbit) cellobiose catabolic process [GO:2000892]; glycosylceramide catabolic process [GO:0046477]; lactose catabolic process [GO:0005990]; quercetin catabolic process [GO:1901733] GO:0000016; GO:0004336; GO:0004348; GO:0005990; GO:0008422; GO:0017042; GO:0042803; GO:0046477; GO:0080079; GO:0098591; GO:0140749; GO:1901733; GO:2000892 44971 XM_029358612.2 7871 5578 3511 7542 7756 Q9Y4W6 0 AFG3-like protein 2 (EC 3.4.24.-) (Paraplegin-like protein) Homo sapiens (Human) axonogenesis [GO:0007409]; calcium import into the mitochondrion [GO:0036444]; cristae formation [GO:0042407]; membrane protein proteolysis [GO:0033619]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrial fusion [GO:0008053]; mitochondrial protein processing [GO:0034982]; muscle cell development [GO:0055001]; myelination [GO:0042552]; nerve development [GO:0021675]; neuromuscular junction development [GO:0007528]; protein autoprocessing [GO:0016540]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of multicellular organism growth [GO:0040014]; righting reflex [GO:0060013] GO:0004176; GO:0004222; GO:0005524; GO:0005739; GO:0005743; GO:0005745; GO:0006508; GO:0007409; GO:0007528; GO:0008053; GO:0008237; GO:0008270; GO:0016485; GO:0016540; GO:0016887; GO:0021675; GO:0033619; GO:0034982; GO:0036444; GO:0040014; GO:0042407; GO:0042552; GO:0051082; GO:0051560; GO:0055001; GO:0060013 44972 XM_044325585.1 2328 4602 174 2564 142 Q8BZ20 2.93e-67 Protein mono-ADP-ribosyltransferase PARP12 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 12) (ARTD12) (Poly [ADP-ribose] polymerase 12) (PARP-12) (Zinc finger CCCH domain-containing protein 1) Mus musculus (Mouse) protein auto-ADP-ribosylation [GO:0070213] GO:0003950; GO:0005634; GO:0016779; GO:0046872; GO:0070213; GO:0140803; GO:1990404 44973 XM_029330871.2 853 825 603 671 314 O35817 2.56e-33 A-kinase anchor protein 14 (AKAP-14) (TAKAP-1.2) (Testis-specific A-kinase-anchoring protein TAKAP-80) Rattus norvegicus (Rat) spermatogenesis [GO:0007283] GO:0005930; GO:0005952; GO:0007283; GO:0034237; GO:0035686; GO:0051018 44974 XM_044313735.1 0 0 6 0 0 NA NA NA NA NA NA 44975 XR_006392201.1 46 17 9 40 23 NA NA NA NA NA NA 44976 XM_029341652.2 0 0 39 37 18 A7MCS3 3.98e-30 UPF0764 protein C16orf89 homolog Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005576; GO:0005829; GO:0016020 44977 XM_044323509.1 113 69 110 65 252 Q4R6W9 5.76e-32 snRNA-activating protein complex subunit 1 (SNAPc subunit 1) (Small nuclear RNA-activating complex polypeptide 1) (snRNA-activating protein complex 43 kDa subunit) (SNAPc 43 kDa subunit) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0003677; GO:0005654; GO:0005730 44978 XM_029333246.2 1960 2385 1057 1275 1312 Q0VC92 5.31e-91 Protein mago nashi homolog 2 Bos taurus (Bovine) mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; RNA splicing [GO:0008380] GO:0000184; GO:0000398; GO:0003723; GO:0005634; GO:0008380; GO:0035145; GO:0051028; GO:0071005; GO:0071006; GO:0071013; GO:1990501 44979 XM_044321720.1 32 64 0 42 131 P54131 7.32e-66 Neuronal acetylcholine receptor subunit alpha-7 Bos taurus (Bovine) calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; cognition [GO:0050890]; ion transmembrane transport [GO:0034220]; negative regulation of tumor necrosis factor production [GO:0032720]; nervous system process [GO:0050877]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAPK cascade [GO:0043410]; regulation of membrane potential [GO:0042391]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271] GO:0001540; GO:0001666; GO:0005231; GO:0005886; GO:0005892; GO:0006816; GO:0006874; GO:0007165; GO:0007268; GO:0007271; GO:0008284; GO:0015464; GO:0015643; GO:0017081; GO:0022848; GO:0030594; GO:0032720; GO:0034220; GO:0035094; GO:0042166; GO:0042391; GO:0042803; GO:0043005; GO:0043410; GO:0045202; GO:0045211; GO:0045766; GO:0050877; GO:0050890; GO:1904315 44980 XM_044313026.1 4 10 11 4 13 NA NA NA NA NA NA 44981 XM_044328622.1 225 89 112 222 212 Q08431 1.7e-22 Lactadherin (Breast epithelial antigen BA46) (HMFG) (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (SED1) [Cleaved into: Lactadherin short form; Medin] Homo sapiens (Human) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005576; GO:0005615; GO:0005788; GO:0007155; GO:0007338; GO:0009897; GO:0016020; GO:0043277; GO:0062023; GO:0070062; GO:1903561 44982 XR_003825242.2 21 40 28 14 9 NA NA NA NA NA NA 44983 XM_029347213.2 808 1615 1098 723 1488 Q99933 1.5e-30 BAG family molecular chaperone regulator 1 (BAG-1) (Bcl-2-associated athanogene 1) Homo sapiens (Human) apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; protein stabilization [GO:0050821] GO:0000774; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006915; GO:0007166; GO:0016020; GO:0031625; GO:0043066; GO:0050821; GO:0051085; GO:0051087 44984 XM_029340182.2 1126 941 1056 1252 339 A8DZE6 9.77e-59 Wilms tumor protein 1-interacting protein homolog (WT1-interacting protein homolog) Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; cloaca development [GO:0035844]; cytoskeleton organization [GO:0007010]; determination of heart left/right asymmetry [GO:0061371]; determination of left/right asymmetry in lateral mesoderm [GO:0003140]; establishment of mitotic spindle orientation [GO:0000132]; heart looping [GO:0001947]; negative regulation of hippo signaling [GO:0035331]; neural crest cell development [GO:0014032]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; regulation of cell morphogenesis [GO:0022604]; regulation of DNA-templated transcription [GO:0006355]; response to hypoxia [GO:0001666]; visceral serous pericardium development [GO:0061032] GO:0000132; GO:0000932; GO:0001666; GO:0001947; GO:0003140; GO:0003714; GO:0005634; GO:0005667; GO:0005912; GO:0006355; GO:0007010; GO:0014032; GO:0022604; GO:0035331; GO:0035844; GO:0036064; GO:0046872; GO:0060271; GO:0061032; GO:0061371; GO:2000637 44985 XM_044313148.1 661 283 216 479 528 NA NA NA NA NA NA 44986 XM_029345478.2 7107 7105 4087 5995 7177 O18413 0 26S proteasome regulatory subunit 8 Drosophila melanogaster (Fruit fly) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005838; GO:0008540; GO:0016887; GO:0036402; GO:0043161 44987 XM_044308433.1 609 512 99 521 259 D3Z8N4 3.16e-164 Kelch-like protein 20 Rattus norvegicus (Rat) Golgi to endosome transport [GO:0006895]; negative regulation of apoptotic process [GO:0043066]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K33-linked ubiquitination [GO:1990390]; protein transport [GO:0015031]; protein ubiquitination [GO:0016567] GO:0003779; GO:0004842; GO:0005737; GO:0005802; GO:0005829; GO:0006895; GO:0015031; GO:0016567; GO:0016605; GO:0019964; GO:0030424; GO:0030425; GO:0031463; GO:0043066; GO:0043161; GO:0048471; GO:1990390 44988 XM_044308433.1 609 512 99 521 259 D3Z8N4 4.39e-23 Kelch-like protein 20 Rattus norvegicus (Rat) Golgi to endosome transport [GO:0006895]; negative regulation of apoptotic process [GO:0043066]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K33-linked ubiquitination [GO:1990390]; protein transport [GO:0015031]; protein ubiquitination [GO:0016567] GO:0003779; GO:0004842; GO:0005737; GO:0005802; GO:0005829; GO:0006895; GO:0015031; GO:0016567; GO:0016605; GO:0019964; GO:0030424; GO:0030425; GO:0031463; GO:0043066; GO:0043161; GO:0048471; GO:1990390 44989 XM_044313237.1 73 65 45 71 48 Q9VH19 2.96e-179 Leishmanolysin-like peptidase (EC 3.4.24.-) (Invadolysin) Drosophila melanogaster (Fruit fly) brain development [GO:0007420]; cell adhesion [GO:0007155]; cell division [GO:0051301]; centrosome duplication [GO:0051298]; chromatin remodeling [GO:0006338]; electron transport chain [GO:0022900]; germ cell migration [GO:0008354]; gonad development [GO:0008406]; imaginal disc development [GO:0007444]; lipid storage [GO:0019915]; mitotic centrosome separation [GO:0007100]; mitotic chromosome condensation [GO:0007076]; mitotic spindle organization [GO:0007052]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; proteolysis [GO:0006508]; regulation of choline O-acetyltransferase activity [GO:1902769] GO:0004222; GO:0005737; GO:0006338; GO:0006508; GO:0007052; GO:0007076; GO:0007100; GO:0007155; GO:0007420; GO:0007444; GO:0008233; GO:0008354; GO:0008406; GO:0016020; GO:0019915; GO:0022900; GO:0045842; GO:0046872; GO:0051298; GO:0051301; GO:1902769 44990 XM_044314416.1 0 22 6 32 0 NA NA NA NA NA NA 44991 XM_029356788.2 20 16 7 17 57 NA NA NA NA NA NA 44992 XM_044315344.1 0 17 0 29 0 NA NA NA NA NA NA 44993 XR_006393469.1 6 23 0 0 2 NA NA NA NA NA NA 44994 XM_029343738.2 104 67 0 4 26 NA NA NA NA NA NA 44995 XM_029341499.2 274 227 6 176 10 NA NA NA NA NA NA 44996 XM_029342836.2 386 504 290 457 376 Q7T0V2 2.37e-31 Ragulator complex protein LAMTOR3-A (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3-A) (Mitogen-activated protein kinase scaffold protein 1) Xenopus laevis (African clawed frog) cellular response to amino acid stimulus [GO:0071230]; positive regulation of TOR signaling [GO:0032008]; protein localization [GO:0008104] GO:0008104; GO:0031902; GO:0032008; GO:0071230; GO:0071986 44997 XM_044325881.1 8 24 6 2 13 NA NA NA NA NA NA 44998 XM_044311414.1 21 2 53 0 134 NA NA NA NA NA NA 44999 XM_044308553.1 0 0 99 75 137 Q5U508 1.09e-128 Tubulin-specific chaperone E (Tubulin-folding cofactor E) Xenopus laevis (African clawed frog) post-chaperonin tubulin folding pathway [GO:0007023] GO:0005737; GO:0005856; GO:0007023; GO:0043014 45000 XM_044328064.1 0 0 16 0 14 P51892 0 DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1) Xenopus laevis (African clawed frog) cell cycle [GO:0007049]; cell division [GO:0051301]; DNA biosynthetic process [GO:0071897]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260] GO:0003677; GO:0003910; GO:0005524; GO:0005634; GO:0006260; GO:0006281; GO:0006310; GO:0007049; GO:0046872; GO:0051301; GO:0071897 45001 XM_044318574.1 0 0 14 0 34 Q68F72 3.87e-81 Solute carrier family 15 member 4 Xenopus laevis (African clawed frog) dipeptide import across plasma membrane [GO:0140206]; innate immune response [GO:0045087]; mast cell homeostasis [GO:0033023]; peptidoglycan transport [GO:0015835]; positive regulation of innate immune response [GO:0045089]; positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [GO:0070430]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of toll-like receptor 7 signaling pathway [GO:0034157]; positive regulation of toll-like receptor 8 signaling pathway [GO:0034161]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; protein transport [GO:0015031]; regulation of isotype switching to IgG isotypes [GO:0048302]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424] GO:0005290; GO:0005765; GO:0015031; GO:0015333; GO:0015647; GO:0015835; GO:0031901; GO:0033023; GO:0034157; GO:0034161; GO:0034165; GO:0036020; GO:0045087; GO:0045089; GO:0048302; GO:0070424; GO:0070430; GO:0070434; GO:0071916; GO:0140206 45002 XM_029341187.2 2968 3275 2000 3509 2018 Q9D4D4 0 Transketolase-like protein 2 (EC 2.2.1.1) Mus musculus (Mouse) NA GO:0004802; GO:0005737; GO:0030976; GO:0046872 45003 XM_044322736.1 9 0 6 6 8 NA NA NA NA NA NA 45004 XM_029338818.2 1211 763 390 862 206 Q7XJJ7 2.08e-93 Fatty acid amide hydrolase (AtFAAH) (EC 3.5.1.99) (N-acylethanolamine amidohydrolase) Arabidopsis thaliana (Mouse-ear cress) defense response to bacterium [GO:0042742]; lipid catabolic process [GO:0016042]; N-acylethanolamine metabolic process [GO:0070291] GO:0000325; GO:0005783; GO:0005789; GO:0005794; GO:0005886; GO:0009536; GO:0016020; GO:0016042; GO:0017064; GO:0042742; GO:0047412; GO:0070291 45005 XR_006398044.1 44 59 14 68 93 NA NA NA NA NA NA 45006 XR_006394310.1 193 152 114 195 224 NA NA NA NA NA NA 45007 XM_044321143.1 0 0 17 71 0 Q9NYT0 1.34e-45 Pleckstrin-2 Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; intracellular signal transduction [GO:0035556]; positive regulation of plasma membrane bounded cell projection assembly [GO:0120034] GO:0005737; GO:0005856; GO:0005886; GO:0031258; GO:0031532; GO:0032266; GO:0035556; GO:0043325; GO:0080025; GO:0120034 45008 XM_029334980.2 1219 287 613 297 520 Q00808 4.57e-30 Vegetative incompatibility protein HET-E-1 Podospora anserina (Pleurage anserina) NA GO:0005525 45009 XM_029334980.2 1219 287 613 297 520 Q00808 5.48e-27 Vegetative incompatibility protein HET-E-1 Podospora anserina (Pleurage anserina) NA GO:0005525 45010 XM_029334980.2 1219 287 613 297 520 Q00808 1.57e-25 Vegetative incompatibility protein HET-E-1 Podospora anserina (Pleurage anserina) NA GO:0005525 45011 XM_029334980.2 1219 287 613 297 520 Q00808 1.31e-22 Vegetative incompatibility protein HET-E-1 Podospora anserina (Pleurage anserina) NA GO:0005525 45012 XM_029332580.2 30 0 0 0 0 NA NA NA NA NA NA 45013 XM_044319388.1 11 19 0 46 31 NA NA NA NA NA NA 45014 XM_044314432.1 24 47 3 134 84 NA NA NA NA NA NA 45015 XR_006396081.1 7 1 15 6 42 NA NA NA NA NA NA 45016 XM_029332546.2 9099 9976 7107 9070 6807 NA NA NA NA NA NA 45017 XM_029338493.2 117 249 149 240 166 P56839 0 Phosphoenolpyruvate phosphomutase (PEP mutase) (PEP phosphomutase) (Phosphoenolpyruvate mutase) (EC 5.4.2.9) Mytilus edulis (Blue mussel) organic phosphonate biosynthetic process [GO:0032923] GO:0032923; GO:0046872; GO:0050188 45018 XM_044309398.1 10 11 4 23 126 NA NA NA NA NA NA 45019 XM_029354829.2 2337 4029 3313 1511 4081 Q9EPL8 0 Importin-7 (Imp7) (Ran-binding protein 7) (RanBP7) Mus musculus (Mouse) innate immune response [GO:0045087]; protein import into nucleus [GO:0006606] GO:0005635; GO:0005654; GO:0005829; GO:0006606; GO:0031267; GO:0042393; GO:0045087; GO:0046332 45020 XM_029341825.2 819 449 515 832 1008 Q9UBS9 8.44e-66 SUN domain-containing ossification factor (Membrane protein CH1) (Protein osteopotentia homolog) (SUN-like protein 1) Homo sapiens (Human) ossification [GO:0001503]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of bone remodeling [GO:0046850] GO:0001503; GO:0005737; GO:0005791; GO:0016020; GO:0030867; GO:0032967; GO:0045669; GO:0046850 45021 XM_044310783.1 81 69 0 118 16 NA NA NA NA NA NA 45022 XM_044325305.1 98 107 36 143 150 P47826 1.52e-119 60S acidic ribosomal protein P0 (60S ribosomal protein L10E) Gallus gallus (Chicken) cytoplasmic translation [GO:0002181]; ribosomal large subunit assembly [GO:0000027] GO:0000027; GO:0002181; GO:0003735; GO:0005634; GO:0022625; GO:0070180 45023 XR_006396748.1 19 54 200 4 127 NA NA NA NA NA NA 45024 XM_029330431.2 465 230 186 559 496 NA NA NA NA NA NA 45025 XM_029350142.2 84 104 120 106 114 Q8N5T2 6.55e-170 TBC1 domain family member 19 Homo sapiens (Human) NA GO:0005096 45026 XM_044317110.1 156 77 75 81 128 NA NA NA NA NA NA 45027 XR_006393616.1 0 20 0 0 2 NA NA NA NA NA NA 45028 XM_044317132.1 1 0 16 2 21 NA NA NA NA NA NA 45029 XM_044328468.1 1 6 3 17 37 Q9EQC4 1.01e-64 Elongation of very long chain fatty acids protein 4 (EC 2.3.1.199) (3-keto acyl-CoA synthase Elovl4) (ELOVL fatty acid elongase 4) (ELOVL FA elongase 4) (Very long chain 3-ketoacyl-CoA synthase 4) (Very long chain 3-oxoacyl-CoA synthase 4) Mus musculus (Mouse) fatty acid elongation, monounsaturated fatty acid [GO:0034625]; fatty acid elongation, polyunsaturated fatty acid [GO:0034626]; fatty acid elongation, saturated fatty acid [GO:0019367]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; sphingolipid biosynthetic process [GO:0030148]; unsaturated fatty acid biosynthetic process [GO:0006636]; very long-chain fatty acid biosynthetic process [GO:0042761] GO:0005783; GO:0005789; GO:0006636; GO:0009922; GO:0019367; GO:0030148; GO:0034625; GO:0034626; GO:0035338; GO:0042761; GO:0102756 45030 XM_029350613.2 1120 1561 808 1693 1765 Q7Z6L1 4.02e-112 Tectonin beta-propeller repeat-containing protein 1 Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; macroautophagy [GO:0016236]; regulation of autophagosome maturation [GO:1901096] GO:0000421; GO:0005654; GO:0005765; GO:0006914; GO:0016236; GO:0031410; GO:0032266; GO:0032991; GO:0043231; GO:0097352; GO:1901096 45031 XM_029350613.2 1120 1561 808 1693 1765 Q7Z6L1 5.78e-69 Tectonin beta-propeller repeat-containing protein 1 Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; macroautophagy [GO:0016236]; regulation of autophagosome maturation [GO:1901096] GO:0000421; GO:0005654; GO:0005765; GO:0006914; GO:0016236; GO:0031410; GO:0032266; GO:0032991; GO:0043231; GO:0097352; GO:1901096 45032 XM_029350613.2 1120 1561 808 1693 1765 Q7Z6L1 2.47e-36 Tectonin beta-propeller repeat-containing protein 1 Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; macroautophagy [GO:0016236]; regulation of autophagosome maturation [GO:1901096] GO:0000421; GO:0005654; GO:0005765; GO:0006914; GO:0016236; GO:0031410; GO:0032266; GO:0032991; GO:0043231; GO:0097352; GO:1901096 45033 XM_029350613.2 1120 1561 808 1693 1765 Q7Z6L1 9.62e-33 Tectonin beta-propeller repeat-containing protein 1 Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; macroautophagy [GO:0016236]; regulation of autophagosome maturation [GO:1901096] GO:0000421; GO:0005654; GO:0005765; GO:0006914; GO:0016236; GO:0031410; GO:0032266; GO:0032991; GO:0043231; GO:0097352; GO:1901096 45034 XM_029342118.2 0 47 0 7 0 P21804 3.76e-80 Fibroblast growth factor receptor 1 (FGFR-1) (bFGF-R-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (Tyrosine kinase receptor CEK1) Gallus gallus (Chicken) epicardial cell to mesenchymal cell transition [GO:0003347]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phospholipase C activity [GO:0010863]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0003347; GO:0004714; GO:0005007; GO:0005524; GO:0005634; GO:0005829; GO:0005886; GO:0007169; GO:0008201; GO:0008284; GO:0010863; GO:0017134; GO:0018108; GO:0031410; GO:0033674; GO:0043235; GO:0043406; GO:0045597; GO:0045893 45035 XM_029342249.2 33 39 28 36 121 NA NA NA NA NA NA 45036 XM_044310846.1 0 0 35 16 52 Q8VD65 1.01e-27 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) Mus musculus (Mouse) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016236; GO:0016241; GO:0030242; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 45037 XM_044326343.1 5 2 7 12 112 NA NA NA NA NA NA 45038 XM_029332302.2 1221 566 727 932 1810 Q0P8I7 2.7e-78 GDP-D-glycero-alpha-D-manno-heptose dehydrogenase (EC 1.1.98.-) Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) capsule polysaccharide biosynthetic process [GO:0045227]; protein homotetramerization [GO:0051289] GO:0003978; GO:0016491; GO:0019003; GO:0042802; GO:0045227; GO:0051289; GO:0070404 45039 XM_029323476.2 406 184 58 54 85 Q86W92 6.87e-104 Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2) Homo sapiens (Human) cell adhesion [GO:0007155]; neuromuscular junction development [GO:0007528]; synapse organization [GO:0050808] GO:0005829; GO:0005886; GO:0005925; GO:0007155; GO:0007528; GO:0045296; GO:0048786; GO:0050808 45040 XM_029323476.2 406 184 58 54 85 Q86W92 1.18e-24 Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2) Homo sapiens (Human) cell adhesion [GO:0007155]; neuromuscular junction development [GO:0007528]; synapse organization [GO:0050808] GO:0005829; GO:0005886; GO:0005925; GO:0007155; GO:0007528; GO:0045296; GO:0048786; GO:0050808 45041 XM_029332710.2 1553 692 577 955 864 O14639 3.55e-74 Actin-binding LIM protein 1 (abLIM-1) (Actin-binding LIM protein family member 1) (Actin-binding double zinc finger protein) (LIMAB1) (Limatin) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cilium assembly [GO:0060271]; cytoskeleton organization [GO:0007010]; lamellipodium assembly [GO:0030032]; visual perception [GO:0007601] GO:0001725; GO:0003779; GO:0005737; GO:0007010; GO:0007601; GO:0009887; GO:0015629; GO:0030027; GO:0030032; GO:0046872; GO:0051015; GO:0060271 45042 XM_044307391.1 46 4 7 25 9 E9Q5R7 6.26e-34 NACHT, LRR and PYD domains-containing protein 12 (Monarch-1) (PYRIN-containing APAF1-like protein 7) (PYPAF7) Mus musculus (Mouse) cellular response to cytokine stimulus [GO:0071345]; dendritic cell migration [GO:0036336]; ERK1 and ERK2 cascade [GO:0070371]; negative regulation of cytokine production [GO:0001818]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of signal transduction [GO:0009968]; negative regulation of Toll signaling pathway [GO:0045751]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of inflammatory response [GO:0050727] GO:0001818; GO:0005524; GO:0005737; GO:0009968; GO:0031953; GO:0032088; GO:0032692; GO:0032715; GO:0036336; GO:0038061; GO:0043122; GO:0043124; GO:0043281; GO:0045345; GO:0045751; GO:0050727; GO:0050728; GO:0070371; GO:0070373; GO:0071345; GO:1901223; GO:1901224 45043 XM_029332515.2 6574 2257 2232 3366 4506 Q8CGY8 0 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.255) (O-GlcNAc transferase subunit p110) (O-linked N-acetylglucosamine transferase 110 kDa subunit) (OGT) Mus musculus (Mouse) apoptotic process [GO:0006915]; cellular response to glucose stimulus [GO:0071333]; cellular response to lipopolysaccharide [GO:0071222]; chromatin organization [GO:0006325]; circadian regulation of gene expression [GO:0032922]; glucosamine metabolic process [GO:0006041]; hemopoiesis [GO:0030097]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; intracellular distribution of mitochondria [GO:0048312]; mitophagy [GO:0000423]; negative regulation of cell death [GO:0060548]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular response to hypoxia [GO:1900038]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein targeting to membrane [GO:0090315]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of stem cell population maintenance [GO:1902455]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cell size [GO:0045793]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of histone H3-K27 methylation [GO:0061087]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of proteolysis [GO:0045862]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein O-linked glycosylation [GO:0006493]; protein processing [GO:0016485]; regulation of dosage compensation by inactivation of X chromosome [GO:1900095]; regulation of gluconeogenesis [GO:0006111]; regulation of glycolytic process [GO:0006110]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of Rac protein signal transduction [GO:0035020]; regulation of synapse assembly [GO:0051963]; regulation of transcription by RNA polymerase II [GO:0006357]; response to insulin [GO:0032868] GO:0000122; GO:0000123; GO:0000423; GO:0000791; GO:0001933; GO:0001934; GO:0003824; GO:0005547; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005829; GO:0005886; GO:0006041; GO:0006110; GO:0006111; GO:0006325; GO:0006357; GO:0006493; GO:0006915; GO:0008080; GO:0010628; GO:0010801; GO:0016485; GO:0016580; GO:0017122; GO:0019904; GO:0030097; GO:0030336; GO:0030512; GO:0031397; GO:0031490; GO:0031966; GO:0032435; GO:0032868; GO:0032922; GO:0032991; GO:0033137; GO:0035020; GO:0042277; GO:0042588; GO:0042802; GO:0043005; GO:0043025; GO:0043981; GO:0043982; GO:0043984; GO:0044545; GO:0044877; GO:0045202; GO:0045793; GO:0045862; GO:0045893; GO:0045944; GO:0046626; GO:0048015; GO:0048312; GO:0051571; GO:0051963; GO:0060548; GO:0061087; GO:0071222; GO:0071333; GO:0090315; GO:0097363; GO:0098696; GO:0098978; GO:0098982; GO:0099523; GO:0099524; GO:0120162; GO:0150048; GO:1900038; GO:1900095; GO:1900182; GO:1902455; GO:1902459; GO:1903428 45044 XM_029332515.2 6574 2257 2232 3366 4506 Q8CGY8 1.83e-51 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.255) (O-GlcNAc transferase subunit p110) (O-linked N-acetylglucosamine transferase 110 kDa subunit) (OGT) Mus musculus (Mouse) apoptotic process [GO:0006915]; cellular response to glucose stimulus [GO:0071333]; cellular response to lipopolysaccharide [GO:0071222]; chromatin organization [GO:0006325]; circadian regulation of gene expression [GO:0032922]; glucosamine metabolic process [GO:0006041]; hemopoiesis [GO:0030097]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; intracellular distribution of mitochondria [GO:0048312]; mitophagy [GO:0000423]; negative regulation of cell death [GO:0060548]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular response to hypoxia [GO:1900038]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein targeting to membrane [GO:0090315]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of stem cell population maintenance [GO:1902455]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cell size [GO:0045793]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of histone H3-K27 methylation [GO:0061087]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of proteolysis [GO:0045862]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein O-linked glycosylation [GO:0006493]; protein processing [GO:0016485]; regulation of dosage compensation by inactivation of X chromosome [GO:1900095]; regulation of gluconeogenesis [GO:0006111]; regulation of glycolytic process [GO:0006110]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of Rac protein signal transduction [GO:0035020]; regulation of synapse assembly [GO:0051963]; regulation of transcription by RNA polymerase II [GO:0006357]; response to insulin [GO:0032868] GO:0000122; GO:0000123; GO:0000423; GO:0000791; GO:0001933; GO:0001934; GO:0003824; GO:0005547; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005829; GO:0005886; GO:0006041; GO:0006110; GO:0006111; GO:0006325; GO:0006357; GO:0006493; GO:0006915; GO:0008080; GO:0010628; GO:0010801; GO:0016485; GO:0016580; GO:0017122; GO:0019904; GO:0030097; GO:0030336; GO:0030512; GO:0031397; GO:0031490; GO:0031966; GO:0032435; GO:0032868; GO:0032922; GO:0032991; GO:0033137; GO:0035020; GO:0042277; GO:0042588; GO:0042802; GO:0043005; GO:0043025; GO:0043981; GO:0043982; GO:0043984; GO:0044545; GO:0044877; GO:0045202; GO:0045793; GO:0045862; GO:0045893; GO:0045944; GO:0046626; GO:0048015; GO:0048312; GO:0051571; GO:0051963; GO:0060548; GO:0061087; GO:0071222; GO:0071333; GO:0090315; GO:0097363; GO:0098696; GO:0098978; GO:0098982; GO:0099523; GO:0099524; GO:0120162; GO:0150048; GO:1900038; GO:1900095; GO:1900182; GO:1902455; GO:1902459; GO:1903428 45045 XM_029347086.2 22 13 7 24 24 Q6P6X9 4.14e-52 Nucleoporin NUP35 (35 kDa nucleoporin) (Nuclear pore complex protein Nup53) (Nucleoporin NUP53) Danio rerio (Zebrafish) (Brachydanio rerio) mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; nuclear pore organization [GO:0006999] GO:0003676; GO:0005543; GO:0006607; GO:0006999; GO:0017056; GO:0031965; GO:0044613; GO:0044615; GO:0051028 45046 XM_029356838.2 55 0 9 16 14 NA NA NA NA NA NA 45047 XM_044316291.1 0 0 0 0 15 NA NA NA NA NA NA 45048 XM_044323284.1 91 10 12 49 50 NA NA NA NA NA NA 45049 XM_044308796.1 36 29 0 77 100 NA NA NA NA NA NA 45050 XM_029339372.2 5175 5687 2771 16412 14292 O18738 1.64e-21 Dystroglycan 1 (Dystroglycan) (Dystrophin-associated glycoprotein 1) [Cleaved into: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta-DG)] Bos taurus (Bovine) axon guidance [GO:0007411]; morphogenesis of an epithelium [GO:0002009]; muscle attachment [GO:0016203]; nerve development [GO:0021675] GO:0002009; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005654; GO:0005737; GO:0005856; GO:0005886; GO:0007411; GO:0016011; GO:0016020; GO:0016203; GO:0021675; GO:0042383; GO:0043236; GO:0045211 45051 XM_044324787.1 2 0 5 0 11 NA NA NA NA NA NA 45052 XM_029343678.2 893 779 534 893 1354 Q0II68 1.22e-179 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase (EC 4.1.1.45) (Picolinate carboxylase) Bos taurus (Bovine) negative regulation of quinolinate biosynthetic process [GO:1904985]; secondary metabolic process [GO:0019748] GO:0001760; GO:0005737; GO:0005829; GO:0008270; GO:0016787; GO:0016831; GO:0019748; GO:1904985 45053 XM_044327854.1 181 158 117 97 134 NA NA NA NA NA NA 45054 XM_044310600.1 1 0 13 0 1 NA NA NA NA NA NA 45055 XM_044309185.1 32 101 255 73 276 NA NA NA NA NA NA 45056 XM_044316930.1 537 0 336 0 328 NA NA NA NA NA NA 45057 XM_044316674.1 60 77 0 0 201 Q8R3B7 1.82e-59 Bromodomain-containing protein 8 Mus musculus (Mouse) cellular response to thyroid hormone stimulus [GO:0097067]; chromatin organization [GO:0006325]; histone acetylation [GO:0016573]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of double-strand break repair [GO:2000779] GO:0000786; GO:0000812; GO:0005654; GO:0005739; GO:0006325; GO:0016573; GO:0030374; GO:0035267; GO:0042981; GO:0043967; GO:0043968; GO:0045893; GO:0045944; GO:0046966; GO:0051726; GO:0097067; GO:1905168; GO:2000779 45058 XM_044316674.1 60 77 0 0 201 Q8R3B7 1.37e-38 Bromodomain-containing protein 8 Mus musculus (Mouse) cellular response to thyroid hormone stimulus [GO:0097067]; chromatin organization [GO:0006325]; histone acetylation [GO:0016573]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of double-strand break repair [GO:2000779] GO:0000786; GO:0000812; GO:0005654; GO:0005739; GO:0006325; GO:0016573; GO:0030374; GO:0035267; GO:0042981; GO:0043967; GO:0043968; GO:0045893; GO:0045944; GO:0046966; GO:0051726; GO:0097067; GO:1905168; GO:2000779 45059 XM_029332908.2 1556 1097 538 1361 1389 Q8AY73 0 Exportin-2 (Exp2) (Cellular apoptosis susceptibility protein) (Chromosome segregation 1-like protein) (Importin-alpha re-exporter) Oreochromis niloticus (Nile tilapia) (Tilapia nilotica) intracellular protein transport [GO:0006886] GO:0005634; GO:0005737; GO:0006886; GO:0031267 45060 XM_029325706.2 41 0 150 2 258 NA NA NA NA NA NA 45061 XM_029329481.2 1373 1137 859 1230 1314 Q5R7A7 0 Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 3) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; protein phosphorylation [GO:0006468] GO:0004674; GO:0005524; GO:0005769; GO:0006468; GO:0035091; GO:0055037; GO:0106310; GO:2001240 45062 XM_044308139.1 11 0 0 2 5 NA NA NA NA NA NA 45063 XM_029326514.2 557 611 655 606 531 Q9D0W5 8.46e-80 Peptidyl-prolyl cis-trans isomerase-like 1 (PPIase) (EC 5.2.1.8) (Rotamase PPIL1) Mus musculus (Mouse) embryonic brain development [GO:1990403]; mRNA splicing, via spliceosome [GO:0000398]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413] GO:0000398; GO:0000413; GO:0003755; GO:0005634; GO:0006457; GO:0016018; GO:0071007; GO:0071013; GO:0097718; GO:1990403 45064 XM_029344443.2 1079 915 649 1046 977 P41976 2.65e-88 Superoxide dismutase [Mn], mitochondrial (EC 1.15.1.1) Bos taurus (Bovine) cellular response to oxidative stress [GO:0034599]; regulation of transcription by RNA polymerase II [GO:0006357]; superoxide metabolic process [GO:0006801] GO:0004784; GO:0005739; GO:0005759; GO:0006357; GO:0006801; GO:0030145; GO:0034599 45065 XR_006392533.1 10 5 7 13 22 NA NA NA NA NA NA 45066 XM_044312826.1 0 0 0 21 0 NA NA NA NA NA NA 45067 XM_044309173.1 7 16 15 5 47 NA NA NA NA NA NA 45068 XM_044323795.1 0 0 13 2 17 NA NA NA NA NA NA 45069 XM_029337520.2 628 529 189 495 291 O02670 1.23e-90 G protein-activated inward rectifier potassium channel 4 (GIRK-4) (Cardiac inward rectifier) (CIR) (Heart KATP channel) (Inward rectifier K(+) channel Kir3.4) (KATP-1) (Potassium channel, inwardly rectifying subfamily J member 5) Sus scrofa (Pig) membrane repolarization during atrial cardiac muscle cell action potential [GO:0098914]; potassium ion import across plasma membrane [GO:1990573]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ion transmembrane transport [GO:0034765] GO:0005242; GO:0005886; GO:0008076; GO:0015467; GO:0034765; GO:0086089; GO:0086091; GO:0098914; GO:1990573 45070 XM_029339831.2 2319 2254 1796 3341 1884 NA NA NA NA NA NA 45071 XM_044309041.1 61 76 67 112 228 NA NA NA NA NA NA 45072 XM_029329573.2 820 856 96 794 1126 A4IGL7 4.58e-91 Peroxidasin (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0005576; GO:0005604; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0031012; GO:0042744; GO:0046872; GO:0051260; GO:0070207; GO:0070831; GO:0071711; GO:0140825 45073 XM_029339594.2 498 300 223 376 424 Q8N129 2.18e-50 Protein canopy homolog 4 Homo sapiens (Human) positive regulation of protein localization to plasma membrane [GO:1903078] GO:0005102; GO:0005576; GO:1903078 45074 XM_029346282.2 430 245 221 455 542 Q7TPD1 0 F-box only protein 11 Mus musculus (Mouse) negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel [GO:1904878]; positive regulation of protein catabolic process [GO:0045732]; protein modification process [GO:0036211]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; sensory perception of sound [GO:0007605]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004842; GO:0005634; GO:0005654; GO:0005694; GO:0005730; GO:0005737; GO:0006511; GO:0007605; GO:0008270; GO:0016274; GO:0016567; GO:0036211; GO:0042981; GO:0045732; GO:1904878 45075 XR_006393274.1 34 31 31 18 10 NA NA NA NA NA NA 45076 XM_029340028.2 1134 2370 1281 1881 1568 NA NA NA NA NA NA 45077 XM_029330851.2 1193 857 721 1102 1007 Q08C72 0 Pre-mRNA-splicing factor CWC22 homolog (Nucampholin homolog) Danio rerio (Zebrafish) (Brachydanio rerio) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0003723; GO:0005634; GO:0005681; GO:0016607; GO:0071005; GO:0071006; GO:0071007; GO:0071013 45078 XM_044308665.1 70 59 16 35 307 Q96AY4 2.55e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 45079 XM_044308665.1 70 59 16 35 307 Q96AY4 3.1e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 45080 XM_044308665.1 70 59 16 35 307 Q96AY4 2.02e-58 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 45081 XM_044308665.1 70 59 16 35 307 Q96AY4 5.81e-58 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 45082 XM_044308665.1 70 59 16 35 307 Q96AY4 7.87e-58 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 45083 XM_044308665.1 70 59 16 35 307 Q96AY4 1.89e-57 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 45084 XM_044308665.1 70 59 16 35 307 Q96AY4 1.69e-56 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 45085 XM_044308665.1 70 59 16 35 307 Q96AY4 6.81e-54 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 45086 XM_044308665.1 70 59 16 35 307 Q96AY4 6.32e-52 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 45087 XM_044308665.1 70 59 16 35 307 Q96AY4 2.51e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 45088 XM_044316996.1 29 17 17 41 35 Q5XGG3 2.39e-47 PIH1 domain-containing protein 2 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA NA 45089 XM_029345435.2 0 0 0 3 6 NA NA NA NA NA NA 45090 XM_029341182.2 8 2 3 6 13 NA NA NA NA NA NA 45091 XM_029337912.2 109 77 148 71 305 D3ZTD8 5.26e-54 Semaphorin-5A (Semaphorin-F) (Sema F) Rattus norvegicus (Rat) axon extension [GO:0048675]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; cell chemotaxis [GO:0060326]; detection of light stimulus involved in visual perception [GO:0050908]; diencephalon development [GO:0021536]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of cell adhesion [GO:0007162]; negative regulation of endothelial cell apoptotic process [GO:2000352]; neural crest cell migration [GO:0001755]; neuron projection extension [GO:1990138]; neuron projection guidance [GO:0097485]; positive chemotaxis [GO:0050918]; positive regulation of actin filament depolymerization [GO:0030836]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein kinase B signaling [GO:0051897]; semaphorin-plexin signaling pathway [GO:0071526]; signal clustering [GO:1990256] GO:0001569; GO:0001755; GO:0001938; GO:0002043; GO:0007162; GO:0007411; GO:0007413; GO:0008046; GO:0016020; GO:0021536; GO:0030215; GO:0030335; GO:0030836; GO:0035373; GO:0043395; GO:0045499; GO:0045545; GO:0045766; GO:0048675; GO:0048754; GO:0048842; GO:0048843; GO:0050908; GO:0050918; GO:0051897; GO:0060326; GO:0071526; GO:0090263; GO:0097485; GO:1990138; GO:1990256; GO:2000352; GO:2001028 45092 XM_044309239.1 33 18 30 23 37 NA NA NA NA NA NA 45093 XM_044325481.1 386 728 432 350 652 Q9JLT4 0 Thioredoxin reductase 2, mitochondrial (EC 1.8.1.9) (Thioredoxin reductase TR3) Mus musculus (Mouse) cell redox homeostasis [GO:0045454]; heart development [GO:0007507]; hemopoiesis [GO:0030097]; response to oxygen radical [GO:0000305] GO:0000305; GO:0004791; GO:0005737; GO:0005739; GO:0005829; GO:0007507; GO:0030097; GO:0030424; GO:0030425; GO:0042803; GO:0043025; GO:0044877; GO:0045454; GO:0050660 45094 XM_029325008.2 132 44 0 0 0 NA NA NA NA NA NA 45095 XR_006391775.1 181 127 17 119 163 NA NA NA NA NA NA 45096 XM_044328625.1 15247 19266 7872 8889 6020 A0A0R4IVA4 9.13e-81 Dual specificity protein phosphatase CDC14AB (EC 3.1.3.16) (EC 3.1.3.48) (CDC14 cell division cycle 14 homolog AB) Danio rerio (Zebrafish) (Brachydanio rerio) cell cycle [GO:0007049]; cell division [GO:0051301]; cilium assembly [GO:0060271]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of cytokinesis [GO:0032467]; protein dephosphorylation [GO:0006470]; regulation of exit from mitosis [GO:0007096] GO:0000226; GO:0000922; GO:0004722; GO:0004725; GO:0005730; GO:0005737; GO:0005813; GO:0006470; GO:0007049; GO:0007096; GO:0008138; GO:0017018; GO:0032467; GO:0051301; GO:0060271; GO:0072686; GO:1902636 45097 XM_044326933.1 65 62 30 44 90 NA NA NA NA NA NA 45098 XM_044327210.1 795 575 350 691 475 P0CS66 1.79e-26 Palmitoyltransferase AKR1 (EC 2.3.1.225) (Ankyrin repeat-containing protein AKR1) Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans) protein palmitoylation [GO:0018345] GO:0000139; GO:0016409; GO:0018345; GO:0019706; GO:0031901 45099 XM_029346067.2 463 417 334 437 305 Q6P5P3 9.19e-29 Tetratricopeptide repeat protein 9C (TPR repeat protein 9C) Rattus norvegicus (Rat) NA NA 45100 XM_029331100.2 3818 2446 2283 3589 3740 P49614 5.13e-168 Beta-hexosaminidase subunit beta (EC 3.2.1.52) (Beta-N-acetylhexosaminidase subunit beta) (Hexosaminidase subunit B) (N-acetyl-beta-glucosaminidase subunit beta) Felis catus (Cat) (Felis silvestris catus) carbohydrate metabolic process [GO:0005975]; ganglioside catabolic process [GO:0006689]; glycosaminoglycan metabolic process [GO:0030203]; single fertilization [GO:0007338] GO:0004563; GO:0005764; GO:0005975; GO:0006689; GO:0007338; GO:0016020; GO:0030203; GO:0060473; GO:0102148 45101 XM_029329566.1 3878 4258 2470 3704 3241 P38117 1.61e-118 Electron transfer flavoprotein subunit beta (Beta-ETF) Homo sapiens (Human) amino acid catabolic process [GO:0009063]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; respiratory electron transport chain [GO:0022904] GO:0005739; GO:0005759; GO:0009055; GO:0009063; GO:0022904; GO:0033539; GO:0045251 45102 XM_029327422.2 394 234 0 87 198 P63138 4.76e-58 Gamma-aminobutyric acid receptor subunit beta-2 (GABA(A) receptor subunit beta-2) Rattus norvegicus (Rat) cellular response to histamine [GO:0071420]; chemical synaptic transmission [GO:0007268]; chemical synaptic transmission, postsynaptic [GO:0099565]; chloride transmembrane transport [GO:1902476]; cochlea development [GO:0090102]; gamma-aminobutyric acid signaling pathway [GO:0007214]; inhibitory synapse assembly [GO:1904862]; inner ear receptor cell development [GO:0060119]; innervation [GO:0060384]; ion transmembrane transport [GO:0034220]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; nervous system process [GO:0050877]; neuron development [GO:0048666]; regulation of membrane potential [GO:0042391]; regulation of neuron apoptotic process [GO:0043523]; regulation of postsynaptic membrane potential [GO:0060078]; sensory perception of sound [GO:0007605]; signal transduction [GO:0007165]; synaptic transmission, GABAergic [GO:0051932] GO:0004890; GO:0005231; GO:0005237; GO:0005254; GO:0005829; GO:0005886; GO:0007165; GO:0007214; GO:0007268; GO:0007605; GO:0016020; GO:0022851; GO:0030594; GO:0030659; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0043523; GO:0043524; GO:0045202; GO:0048666; GO:0048787; GO:0050877; GO:0051932; GO:0060078; GO:0060119; GO:0060384; GO:0071420; GO:0090102; GO:0098978; GO:0098982; GO:0099507; GO:0099565; GO:0099634; GO:1901215; GO:1902476; GO:1902710; GO:1902711; GO:1904315; GO:1904862 45103 XM_044308470.1 23 7 7 18 12 NA NA NA NA NA NA 45104 XR_006396750.1 967 403 514 699 93 NA NA NA NA NA NA 45105 XR_006392240.1 11 0 8 0 25 NA NA NA NA NA NA 45106 XM_029342196.2 192 0 34 0 566 NA NA NA NA NA NA 45107 XM_044312110.1 1 0 6 12 4 NA NA NA NA NA NA 45108 XM_029353837.2 1077 653 556 460 818 Q923U9 1.73e-92 Solute carrier family 40 member 1 (CAR1) (Cell adhesion regulator) (Ferroportin-1) Rattus norvegicus (Rat) apoptotic process [GO:0006915]; cellular iron ion homeostasis [GO:0006879]; endothelium development [GO:0003158]; establishment of localization in cell [GO:0051649]; iron ion export across plasma membrane [GO:1903988]; iron ion homeostasis [GO:0055072]; iron ion transmembrane transport [GO:0034755]; iron ion transport [GO:0006826]; lymphocyte homeostasis [GO:0002260]; multicellular organismal iron ion homeostasis [GO:0060586]; negative regulation of apoptotic process [GO:0043066]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; spleen development [GO:0048536]; spleen trabecula formation [GO:0060345]; transcription by RNA polymerase II [GO:0006366] GO:0002260; GO:0003158; GO:0005381; GO:0005886; GO:0006366; GO:0006826; GO:0006879; GO:0006915; GO:0008021; GO:0015093; GO:0016323; GO:0017046; GO:0034395; GO:0034755; GO:0042802; GO:0043066; GO:0045944; GO:0046872; GO:0048536; GO:0051649; GO:0055072; GO:0060345; GO:0060586; GO:1903988 45109 XM_029353837.2 1077 653 556 460 818 Q923U9 1.57e-22 Solute carrier family 40 member 1 (CAR1) (Cell adhesion regulator) (Ferroportin-1) Rattus norvegicus (Rat) apoptotic process [GO:0006915]; cellular iron ion homeostasis [GO:0006879]; endothelium development [GO:0003158]; establishment of localization in cell [GO:0051649]; iron ion export across plasma membrane [GO:1903988]; iron ion homeostasis [GO:0055072]; iron ion transmembrane transport [GO:0034755]; iron ion transport [GO:0006826]; lymphocyte homeostasis [GO:0002260]; multicellular organismal iron ion homeostasis [GO:0060586]; negative regulation of apoptotic process [GO:0043066]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; spleen development [GO:0048536]; spleen trabecula formation [GO:0060345]; transcription by RNA polymerase II [GO:0006366] GO:0002260; GO:0003158; GO:0005381; GO:0005886; GO:0006366; GO:0006826; GO:0006879; GO:0006915; GO:0008021; GO:0015093; GO:0016323; GO:0017046; GO:0034395; GO:0034755; GO:0042802; GO:0043066; GO:0045944; GO:0046872; GO:0048536; GO:0051649; GO:0055072; GO:0060345; GO:0060586; GO:1903988 45110 XM_029330590.2 22 0 9 13 2 O95395 1.22e-62 Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 (EC 2.4.1.102) (EC 2.4.1.148) (EC 2.4.1.150) (C2GnT-mucin type) (C2GnT-M) (hC2GnT-M) (Core 2/core 4 beta-1,6-N-acetylglucosaminyltransferase) (C2/4GnT) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; intestinal absorption [GO:0050892]; kidney morphogenesis [GO:0060993]; O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493]; tissue morphogenesis [GO:0048729] GO:0000139; GO:0003829; GO:0005975; GO:0006493; GO:0008109; GO:0008375; GO:0016020; GO:0016266; GO:0048729; GO:0050892; GO:0060993; GO:0070062; GO:0106325; GO:0106326 45111 XM_044317362.1 5 342 86 3 39 NA NA NA NA NA NA 45112 XM_044322507.1 106 13 80 167 12 NA NA NA NA NA NA 45113 XM_044326147.1 12 0 0 0 11 Q15818 1.75e-36 Neuronal pentraxin-1 (NP1) (Neuronal pentraxin I) (NP-I) Homo sapiens (Human) axonogenesis involved in innervation [GO:0060385]; cellular response to glucose stimulus [GO:0071333]; cellular response to potassium ion [GO:0035865]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; mitochondrial transport [GO:0006839]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic density assembly [GO:0097107]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962] GO:0005739; GO:0005886; GO:0006839; GO:0007268; GO:0007417; GO:0030133; GO:0035865; GO:0043005; GO:0043083; GO:0043653; GO:0046872; GO:0060385; GO:0071333; GO:0097107; GO:0098962; GO:0098978; GO:0099645 45114 XM_044312679.1 9 0 0 4 0 NA NA NA NA NA NA 45115 XM_029352300.2 4230 4898 2783 4754 3422 P07560 5.16e-30 Ras-related protein SEC4 (Suppressor of RHO3 protein 6) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) ascospore-type prospore assembly [GO:0031321]; autophagy [GO:0006914]; exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; membrane addition at site of cytokinesis [GO:0007107]; protein localization to plasma membrane [GO:0072659]; protein secretion [GO:0009306]; regulation of exocytosis [GO:0017157]; vesicle docking involved in exocytosis [GO:0006904]; vesicle fusion [GO:0006906] GO:0000131; GO:0003924; GO:0005525; GO:0005739; GO:0005741; GO:0005768; GO:0005783; GO:0005886; GO:0005935; GO:0006887; GO:0006893; GO:0006904; GO:0006906; GO:0006914; GO:0007107; GO:0009306; GO:0017157; GO:0030133; GO:0030658; GO:0031321; GO:0031982; GO:0043231; GO:0043332; GO:0072659 45116 XR_006397149.1 9719 5739 3439 9293 7187 Q90413 1.32e-67 Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) Danio rerio (Zebrafish) (Brachydanio rerio) fibroblast growth factor receptor signaling pathway [GO:0008543]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of kinase activity [GO:0033674]; regulation of bile acid biosynthetic process [GO:0070857]; regulation of hematopoietic stem cell differentiation [GO:1902036]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0004714; GO:0005007; GO:0005524; GO:0005768; GO:0005783; GO:0005886; GO:0007169; GO:0008543; GO:0017134; GO:0033674; GO:0043235; GO:0070374; GO:0070857; GO:1902036 45117 XR_006397149.1 9719 5739 3439 9293 7187 Q90413 1.32e-67 Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) Danio rerio (Zebrafish) (Brachydanio rerio) fibroblast growth factor receptor signaling pathway [GO:0008543]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of kinase activity [GO:0033674]; regulation of bile acid biosynthetic process [GO:0070857]; regulation of hematopoietic stem cell differentiation [GO:1902036]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0004714; GO:0005007; GO:0005524; GO:0005768; GO:0005783; GO:0005886; GO:0007169; GO:0008543; GO:0017134; GO:0033674; GO:0043235; GO:0070374; GO:0070857; GO:1902036 45118 XR_006391397.1 38 17 12 16 5 NA NA NA NA NA NA 45119 XM_029334617.2 69 0 63 39 6 W8W138 3.22e-39 Beta-secretase (EC 3.4.23.-) Strongylocentrotus purpuratus (Purple sea urchin) amyloid-beta metabolic process [GO:0050435]; membrane protein ectodomain proteolysis [GO:0006509]; proteolysis [GO:0006508] GO:0004190; GO:0005768; GO:0005802; GO:0005886; GO:0006508; GO:0006509; GO:0050435 45120 XM_029329306.2 111 28 0 55 0 NA NA NA NA NA NA 45121 XM_044321080.1 0 0 0 0 16 NA NA NA NA NA NA 45122 XM_044326474.1 15 32 0 245 22 Q5IS99 1.18e-43 Caspase-3 (CASP-3) (EC 3.4.22.56) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12] Saimiri boliviensis boliviensis (Bolivian squirrel monkey) cellular response to staurosporine [GO:0072734]; erythrocyte differentiation [GO:0030218]; intracellular signal transduction [GO:0035556]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of amyloid-beta formation [GO:1902004]; proteolysis [GO:0006508]; regulation of protein stability [GO:0031647] GO:0004175; GO:0005634; GO:0005829; GO:0006508; GO:0030218; GO:0031647; GO:0035556; GO:0048011; GO:0072734; GO:0097153; GO:0097199; GO:0097200; GO:1902004 45123 XM_044318117.1 81 84 121 193 226 NA NA NA NA NA NA 45124 XM_044312176.1 91 50 29 6 81 O60290 3.5e-36 Zinc finger protein 862 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006355; GO:0046872; GO:0046983 45125 XM_044327694.1 68 57 8 9 33 NA NA NA NA NA NA 45126 XM_044314067.1 66 19 11 8 7 NA NA NA NA NA NA 45127 XM_029331202.2 176 148 134 106 93 NA NA NA NA NA NA 45128 XM_044326370.1 36 5 4 31 27 Q9TTT5 1.31e-89 Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3) Oryctolagus cuniculus (Rabbit) protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0008076; GO:0030425; GO:0034765; GO:0042383; GO:0046872; GO:0051260 45129 XM_044328495.1 61 15 24 3 4 P49286 5.36e-31 Melatonin receptor type 1B (Mel-1B-R) (Mel1b receptor) Homo sapiens (Human) camera-type eye development [GO:0043010]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; glucose homeostasis [GO:0042593]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of insulin secretion [GO:0046676]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transmission of nerve impulse [GO:0051970]; negative regulation of vasoconstriction [GO:0045906]; positive regulation of circadian sleep/wake cycle, non-REM sleep [GO:0046010]; positive regulation of transmission of nerve impulse [GO:0051971]; regulation of insulin secretion [GO:0050796]; regulation of neuronal action potential [GO:0098908] GO:0004930; GO:0005886; GO:0007186; GO:0007187; GO:0007268; GO:0008502; GO:0010754; GO:0042593; GO:0043010; GO:0043524; GO:0045202; GO:0045906; GO:0046010; GO:0046676; GO:0050796; GO:0051481; GO:0051970; GO:0051971; GO:0098908; GO:1902260 45130 XM_029338432.2 40 27 11 12 16 Q5R5S1 8.4e-84 F-box only protein 21 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677 45131 XM_029355519.2 58 30 0 0 0 Q8NFF2 3.88e-117 Sodium/potassium/calcium exchanger 4 (Na(+)/K(+)/Ca(2+)-exchange protein 4) (Solute carrier family 24 member 4) Homo sapiens (Human) amelogenesis [GO:0097186]; calcium ion export across plasma membrane [GO:1990034]; calcium ion homeostasis [GO:0055074]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; cellular response to high light intensity [GO:0071486]; cone photoresponse recovery [GO:0036368]; detection of chemical stimulus involved in sensory perception of smell [GO:0050911]; drinking behavior [GO:0042756]; enamel mineralization [GO:0070166]; ion transport [GO:0006811]; membrane repolarization [GO:0086009]; negative regulation of calcium-mediated signaling [GO:0050849]; olfactory nerve maturation [GO:0021630]; phototransduction [GO:0007602]; positive regulation of gene expression [GO:0010628]; potassium ion transmembrane transport [GO:0071805]; regulation of eating behavior [GO:1903998]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; regulation of signaling receptor activity [GO:0010469]; response to high light intensity [GO:0009644]; response to melanocyte-stimulating hormone [GO:1990680]; response to odorant [GO:1990834]; sensory perception of smell [GO:0007608]; sodium ion transmembrane transport [GO:0035725] GO:0005262; GO:0005516; GO:0005737; GO:0005886; GO:0006811; GO:0006874; GO:0007602; GO:0007608; GO:0008273; GO:0008277; GO:0009644; GO:0010469; GO:0010628; GO:0015293; GO:0016020; GO:0016324; GO:0021630; GO:0031982; GO:0035725; GO:0036368; GO:0042756; GO:0048306; GO:0050849; GO:0050911; GO:0055074; GO:0070166; GO:0070588; GO:0071486; GO:0071805; GO:0086009; GO:0097186; GO:0098703; GO:0120199; GO:1903998; GO:1990034; GO:1990680; GO:1990834 45132 XM_029345860.2 425 313 219 481 1138 Q8UW76 8.66e-110 T-box transcription factor TBX20 (T-box protein 20) (cTbx20) Gallus gallus (Chicken) aortic valve morphogenesis [GO:0003180]; atrial septum morphogenesis [GO:0060413]; atrioventricular canal development [GO:0036302]; blood circulation [GO:0008015]; branching involved in blood vessel morphogenesis [GO:0001569]; cardiac chamber formation [GO:0003207]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac right ventricle morphogenesis [GO:0003215]; cell fate specification [GO:0001708]; cell migration involved in heart development [GO:0060973]; cell proliferation involved in heart valve development [GO:2000793]; dorsal/ventral pattern formation [GO:0009953]; embryonic heart tube elongation [GO:0036306]; endocardial cushion formation [GO:0003272]; foramen ovale closure [GO:0035922]; heart looping [GO:0001947]; mesenchymal cell development [GO:0014031]; motor neuron migration [GO:0097475]; muscle contraction [GO:0006936]; negative regulation of gene expression [GO:0010629]; negative regulation of SMAD protein complex assembly [GO:0010991]; negative regulation of transcription by RNA polymerase II [GO:0000122]; outflow tract septum morphogenesis [GO:0003148]; pericardium morphogenesis [GO:0003344]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell migration [GO:0030335]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of gene expression [GO:0010628]; pulmonary valve formation [GO:0003193]; pulmonary vein morphogenesis [GO:0060577]; regulation of transcription by RNA polymerase II [GO:0006357]; tricuspid valve development [GO:0003175]; vasculogenesis [GO:0001570]; visceral motor neuron differentiation [GO:0021524] GO:0000122; GO:0000978; GO:0000981; GO:0001228; GO:0001569; GO:0001570; GO:0001708; GO:0001947; GO:0003148; GO:0003175; GO:0003180; GO:0003193; GO:0003207; GO:0003215; GO:0003272; GO:0003344; GO:0005634; GO:0005737; GO:0006357; GO:0006936; GO:0008015; GO:0009953; GO:0010628; GO:0010629; GO:0010718; GO:0010991; GO:0014031; GO:0021524; GO:0030335; GO:0030513; GO:0035922; GO:0036302; GO:0036306; GO:0055008; GO:0060045; GO:0060413; GO:0060577; GO:0060973; GO:0061629; GO:0097475; GO:2000793 45133 XM_044316057.1 0 0 11 0 4 NA NA NA NA NA NA 45134 XM_044308927.1 123 8 50 1 61 NA NA NA NA NA NA 45135 XM_029340881.2 2137 1707 1184 2189 3019 P26686 4.05e-60 Serine-arginine protein 55 (SRP55) (52 kDa bracketing protein) (B52 protein) (Protein enhancer of deformed) Drosophila melanogaster (Fruit fly) defense response to virus [GO:0051607]; mitotic cell cycle [GO:0000278]; mitotic G1/S transition checkpoint signaling [GO:0044819]; mRNA splicing, via spliceosome [GO:0000398]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of gene expression [GO:0010468]; regulation of mRNA 3'-end processing [GO:0031440]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of transcriptional start site selection at RNA polymerase II promoter [GO:0001178]; RNA splicing [GO:0008380] GO:0000278; GO:0000381; GO:0000398; GO:0000791; GO:0001178; GO:0003723; GO:0003729; GO:0005634; GO:0005700; GO:0008380; GO:0010468; GO:0016607; GO:0031440; GO:0044819; GO:0048024; GO:0051607; GO:0071011; GO:0071013 45136 XM_044307978.1 14 1 4 0 42 NA NA NA NA NA NA 45137 XM_029348944.2 219 68 0 51 45 O54852 3.9e-102 Potassium voltage-gated channel subfamily H member 7 (Ether-a-go-go-related gene potassium channel 3) (ERG-3) (Eag-related protein 3) (Ether-a-go-go-related protein 3) (Voltage-gated potassium channel subunit Kv11.3) Rattus norvegicus (Rat) circadian rhythm [GO:0007623]; membrane repolarization during action potential [GO:0086011]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391] GO:0005242; GO:0005249; GO:0005267; GO:0005886; GO:0006813; GO:0007623; GO:0034765; GO:0042391; GO:0044877; GO:0071805; GO:0086011 45138 XM_029347812.2 20 4 7 27 27 NA NA NA NA NA NA 45139 XM_044318268.1 5 811 596 1450 100 O70521 2.72e-37 Regulator of G-protein signaling 19 (RGS19) (G-alpha-interacting protein) (GAIP) Rattus norvegicus (Rat) negative regulation of signal transduction [GO:0009968]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; response to ethanol [GO:0045471] GO:0000139; GO:0001965; GO:0005096; GO:0005737; GO:0005903; GO:0008277; GO:0009968; GO:0016020; GO:0030136; GO:0045121; GO:0045471 45140 XM_029355316.2 148 157 87 187 92 P60204 1.16e-42 Calmodulin (CaM) Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) regulation of cell cycle [GO:0051726]; spindle pole body organization [GO:0051300]; spore germination [GO:0009847] GO:0001411; GO:0005509; GO:0005823; GO:0009847; GO:0030234; GO:0051300; GO:0051726 45141 XM_044313863.1 679 823 137 769 713 NA NA NA NA NA NA 45142 XM_044320001.1 16 21 1 25 10 NA NA NA NA NA NA 45143 XM_029332524.2 1002 788 647 1473 1893 B3EWZ9 0 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 45144 XM_044315189.1 121 19 8 83 85 NA NA NA NA NA NA 45145 XM_044315953.1 121 403 253 430 0 NA NA NA NA NA NA 45146 XM_029343186.2 895 647 476 741 821 Q8IZU2 0 WD repeat-containing protein 17 Homo sapiens (Human) NA NA 45147 XM_044327713.1 7 6 11 42 56 Q9UTA9 4.12e-22 Uncharacterized methyltransferase C25B8.09 (EC 2.1.1.-) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) cellular carbohydrate metabolic process [GO:0044262]; cellular detoxification [GO:1990748]; methylation [GO:0032259] GO:0005634; GO:0005829; GO:0008168; GO:0032259; GO:0044262; GO:0046547; GO:1990748 45148 XM_029333750.2 1291 1397 600 1033 1069 Q5TD94 1.35e-154 Radial spoke head protein 4 homolog A (Radial spoke head-like protein 3) Homo sapiens (Human) axoneme assembly [GO:0035082]; cilium movement [GO:0003341]; cilium movement involved in cell motility [GO:0060294]; maintenance of ciliary planar beating movement pattern [GO:0120221]; radial spoke assembly [GO:0062177] GO:0001534; GO:0001535; GO:0003341; GO:0005654; GO:0005730; GO:0005930; GO:0031514; GO:0035082; GO:0060294; GO:0062177; GO:0120221 45149 XM_029345715.2 396 225 311 399 553 A7SCH8 0 Kynureninase (EC 3.7.1.3) (L-kynurenine hydrolase) Nematostella vectensis (Starlet sea anemone) 'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; anthranilate metabolic process [GO:0043420]; L-kynurenine catabolic process [GO:0097053]; quinolinate biosynthetic process [GO:0019805]; tryptophan catabolic process to kynurenine [GO:0019441] GO:0005737; GO:0019441; GO:0019805; GO:0030170; GO:0030429; GO:0034354; GO:0043420; GO:0061981; GO:0097053 45150 XM_029337379.2 210 230 151 223 253 P56380 2.06e-42 Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] (EC 3.6.1.17) (Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase) (Ap4A hydrolase) (Ap4Aase) (Diadenosine tetraphosphatase) (Nucleoside diphosphate-linked moiety X motif 2) (Nudix motif 2) Mus musculus (Mouse) AMP biosynthetic process [GO:0006167]; apoptotic process [GO:0006915]; ATP biosynthetic process [GO:0006754] GO:0004081; GO:0005525; GO:0005739; GO:0006167; GO:0006754; GO:0006915 45151 XM_029328747.2 45 52 56 103 68 Q5XGI1 4.61e-80 Kidney mitochondrial carrier protein 1 (Solute carrier family 25 member 30) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) mitochondrial transport [GO:0006839] GO:0005743; GO:0006839 45152 XM_044313522.1 0 0 8 0 0 A0A0C2SRU0 2.53e-79 Decarboxylase iboD (EC 4.1.1.-) (Ibotenic acid biosynthesis cluster protein D) Amanita muscaria (strain Koide BX008) phospholipid biosynthetic process [GO:0008654] GO:0004609; GO:0008654 45153 XM_044321658.1 207 7 150 217 197 Q7RTR2 2.47e-41 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 45154 XM_044328002.1 1409 2430 1258 2868 3341 Q99758 0 Phospholipid-transporting ATPase ABCA3 (EC 7.6.2.1) (ABC-C transporter) (ATP-binding cassette sub-family A member 3) (ATP-binding cassette transporter 3) (ATP-binding cassette 3) (Xenobiotic-transporting ATPase ABCA3) (EC 7.6.2.2) [Cleaved into: 150 Kda mature form] Homo sapiens (Human) lipid transport [GO:0006869]; lung development [GO:0030324]; organelle assembly [GO:0070925]; phosphatidylcholine metabolic process [GO:0046470]; phosphatidylglycerol metabolic process [GO:0046471]; phospholipid homeostasis [GO:0055091]; phospholipid transport [GO:0015914]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of phospholipid efflux [GO:1902995]; positive regulation of phospholipid transport [GO:2001140]; positive regulation of protein homooligomerization [GO:0032464]; protein metabolic process [GO:0019538]; regulation of lipid biosynthetic process [GO:0046890]; regulation of phosphatidylcholine metabolic process [GO:0150172]; response to glucocorticoid [GO:0051384]; response to xenobiotic stimulus [GO:0009410]; surfactant homeostasis [GO:0043129]; xenobiotic export from cell [GO:0046618]; xenobiotic transmembrane transport [GO:0006855]; xenobiotic transport [GO:0042908] GO:0005319; GO:0005524; GO:0005615; GO:0005765; GO:0005770; GO:0005886; GO:0006855; GO:0006869; GO:0008559; GO:0009410; GO:0010875; GO:0015914; GO:0016887; GO:0019538; GO:0030324; GO:0030659; GO:0032464; GO:0032585; GO:0042599; GO:0042626; GO:0042908; GO:0043129; GO:0043231; GO:0046470; GO:0046471; GO:0046618; GO:0046890; GO:0051384; GO:0055091; GO:0070925; GO:0097208; GO:0097232; GO:0097233; GO:0120019; GO:0140345; GO:0150172; GO:1902995; GO:2001140 45155 XM_044327089.1 28 0 0 35 5 NA NA NA NA NA NA 45156 XM_044315412.1 193 155 114 253 195 NA NA NA NA NA NA 45157 XM_044329000.1 24 5 0 11 0 NA NA NA NA NA NA 45158 XM_029338205.2 115 74 230 52 126 NA NA NA NA NA NA 45159 XM_029327545.2 33991 32891 19034 30880 11352 NA NA NA NA NA NA 45160 XM_029339720.2 102 465 88 4 0 Q7Z7A1 5.11e-79 Centriolin (Centrosomal protein 1) (Centrosomal protein of 110 kDa) (Cep110) Homo sapiens (Human) aorta development [GO:0035904]; cell cycle [GO:0007049]; cell division [GO:0051301]; coronary vasculature development [GO:0060976]; kidney development [GO:0001822]; ventricular septum development [GO:0003281] GO:0001822; GO:0003281; GO:0005813; GO:0005815; GO:0005829; GO:0007049; GO:0016020; GO:0034451; GO:0035904; GO:0048471; GO:0051301; GO:0060976; GO:0090543; GO:0090619; GO:0097431; GO:0120103 45161 XM_044326643.1 6 0 4 0 1 NA NA NA NA NA NA 45162 XM_044325812.1 43 86 40 354 425 NA NA NA NA NA NA 45163 XM_044312737.1 10 135 2 25 16 NA NA NA NA NA NA 45164 XM_044321694.1 0 19 262 5 0 Q63415 8.05e-112 Proprotein convertase subtilisin/kexin type 6 (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin-like proprotein convertase 4) (SPC4) (Subtilisin/kexin-like protease PACE4) Rattus norvegicus (Rat) determination of left/right symmetry [GO:0007368]; glycoprotein metabolic process [GO:0009100]; nerve growth factor production [GO:0032902]; peptide hormone processing [GO:0016486]; protein processing [GO:0016485]; secretion by cell [GO:0032940]; zygotic determination of anterior/posterior axis, embryo [GO:0007354] GO:0004175; GO:0004252; GO:0005615; GO:0007354; GO:0007368; GO:0008201; GO:0009100; GO:0009986; GO:0016020; GO:0016485; GO:0016486; GO:0032902; GO:0032940; GO:0048406; GO:0062023 45165 XM_044319443.1 32 61 63 63 0 NA NA NA NA NA NA 45166 XM_044312743.1 1496 666 823 1298 1590 Q8K4L3 1.2e-167 Supervillin (Archvillin) (p205/p250) Mus musculus (Mouse) actin filament severing [GO:0051014]; actin polymerization or depolymerization [GO:0008154]; barbed-end actin filament capping [GO:0051016]; positive regulation of cytokinesis [GO:0032467]; skeletal muscle tissue development [GO:0007519] GO:0002102; GO:0005546; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0007519; GO:0008154; GO:0015629; GO:0030496; GO:0032154; GO:0032467; GO:0036449; GO:0042995; GO:0043034; GO:0051014; GO:0051015; GO:0051016; GO:0070161 45167 XM_029337956.2 0 65 35 20 0 Q29611 5.79e-118 Battenin (Protein CLN3) Canis lupus familiaris (Dog) (Canis familiaris) amyloid precursor protein catabolic process [GO:0042987]; autophagosome-lysosome fusion [GO:0061909]; cellular water homeostasis [GO:0009992]; glycerophospholipid biosynthetic process [GO:0046474]; glycolipid transport [GO:0046836]; Golgi to lysosome transport [GO:0090160]; L-arginine transmembrane transport [GO:1903826]; learning or memory [GO:0007611]; lysosomal lumen acidification [GO:0007042]; lysosomal lumen pH elevation [GO:0035752]; lysosomal protein catabolic process [GO:1905146]; negative regulation of apoptotic process [GO:0043066]; phagosome-lysosome docking [GO:0090384]; phagosome-lysosome fusion [GO:0090385]; plasma membrane raft organization [GO:0044857]; positive regulation of caveolin-mediated endocytosis [GO:2001288]; positive regulation of Golgi to plasma membrane protein transport [GO:0042998]; positive regulation of pinocytosis [GO:0048549]; receptor-mediated endocytosis [GO:0006898]; regulation of arginine biosynthetic process [GO:1900079]; regulation of autophagosome maturation [GO:1901096]; regulation of cellular response to osmotic stress [GO:0106049]; regulation of cytoskeleton organization [GO:0051493]; regulation of fibroblast migration [GO:0010762]; regulation of modification of synaptic structure [GO:1905244]; regulation of phagosome maturation [GO:1905162]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of protein processing [GO:0070613]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic transmission, GABAergic [GO:0032228]; regulation of synaptic transmission, glutamatergic [GO:0051966]; renal potassium excretion [GO:0036359]; vesicle transport along microtubule [GO:0047496] GO:0000139; GO:0005634; GO:0005737; GO:0005764; GO:0005765; GO:0005769; GO:0005770; GO:0005783; GO:0005789; GO:0005794; GO:0005795; GO:0005802; GO:0005829; GO:0005886; GO:0005901; GO:0006898; GO:0007042; GO:0007611; GO:0008021; GO:0009992; GO:0010762; GO:0016020; GO:0031901; GO:0032228; GO:0035752; GO:0036359; GO:0042987; GO:0042998; GO:0043005; GO:0043066; GO:0044754; GO:0044857; GO:0045121; GO:0046474; GO:0046836; GO:0047496; GO:0048172; GO:0048549; GO:0051493; GO:0051861; GO:0051966; GO:0055037; GO:0061909; GO:0070613; GO:0090160; GO:0090384; GO:0090385; GO:0106049; GO:0120146; GO:1900079; GO:1901096; GO:1903076; GO:1903826; GO:1905146; GO:1905162; GO:1905244; GO:2001288 45168 XM_029341953.2 45 4 16 4 53 A9JS51 5.29e-55 Protein FAM166B Xenopus laevis (African clawed frog) NA GO:0005879 45169 XM_029327292.2 1950 2404 1005 855 666 NA NA NA NA NA NA 45170 XM_029350944.2 0 27 18 9 9 NA NA NA NA NA NA 45171 XM_044327456.1 0 0 23 0 0 F8J3H2 3.97e-24 NA NA NA NA 45172 XR_006393539.1 488 30 69 65 50 NA NA NA NA NA NA 45173 XM_044322789.1 84 15 7 16 33 NA NA NA NA NA NA 45174 XM_029352244.2 680 453 150 441 533 Q9V576 1.01e-42 Putative phosphatidate phosphatase (EC 3.1.3.4) (Germ cell guidance factor) (Phosphatidic acid phosphatase type 2) (Protein wunen) Drosophila melanogaster (Fruit fly) defense response to Gram-negative bacterium [GO:0050829]; ectopic germ cell programmed cell death [GO:0035234]; germ cell migration [GO:0008354]; germ cell repulsion [GO:0035233]; negative regulation of innate immune response [GO:0045824]; open tracheal system development [GO:0007424]; phospholipid dephosphorylation [GO:0046839]; phospholipid metabolic process [GO:0006644]; pole cell migration [GO:0007280]; septate junction assembly [GO:0019991]; signal transduction [GO:0007165] GO:0005886; GO:0005918; GO:0006644; GO:0007165; GO:0007280; GO:0007424; GO:0008195; GO:0008354; GO:0016791; GO:0019991; GO:0035233; GO:0035234; GO:0042577; GO:0045177; GO:0045824; GO:0046839; GO:0050829 45175 XM_029334442.2 175 136 96 135 66 NA NA NA NA NA NA 45176 XR_006394933.1 163 0 315 84 0 NA NA NA NA NA NA 45177 XM_029324069.2 3198 3402 1104 5125 4611 P23506 2.7e-84 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PIMT) (EC 2.1.1.77) (L-isoaspartyl protein carboxyl methyltransferase) (Protein L-isoaspartyl/D-aspartyl methyltransferase) (Protein-beta-aspartate methyltransferase) Mus musculus (Mouse) negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; protein methylation [GO:0006479]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500] GO:0004719; GO:0005615; GO:0005737; GO:0005829; GO:0006479; GO:0008757; GO:0010667; GO:0016323; GO:0031526; GO:0043005; GO:0043204; GO:0046498; GO:0046500 45178 XM_029344011.2 0 40 114 0 88 A1L1W9 1.8e-70 Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10) Danio rerio (Zebrafish) (Brachydanio rerio) aromatic amino acid transport [GO:0015801]; thyroid hormone transport [GO:0070327] GO:0005302; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0070327 45179 XM_044316546.1 7 7 12 5 14 NA NA NA NA NA NA 45180 XM_029339456.2 97 338 367 532 760 NA NA NA NA NA NA 45181 XM_029347838.2 806 632 498 915 371 Q6GM44 6.57e-115 E3 ubiquitin-protein ligase MARCHF5 (EC 2.3.2.27) (Membrane-associated RING finger protein 5) (Membrane-associated RING-CH protein V) (MARCH-V) (RING-type E3 ubiquitin transferase MARCHF5) Xenopus laevis (African clawed frog) protein autoubiquitination [GO:0051865]; regulation of mitochondrial fission [GO:0090140] GO:0005741; GO:0005783; GO:0005789; GO:0008270; GO:0051865; GO:0061630; GO:0090140 45182 XM_044308093.1 2335 1943 1603 2257 2382 P70627 1.52e-171 Glutamate carboxypeptidase 2 (EC 3.4.17.21) (Folate hydrolase 1) (Folylpoly-gamma-glutamate carboxypeptidase) (FGCP) (Glutamate carboxypeptidase II) (GCPII) (Membrane glutamate carboxypeptidase) (mGCP) (N-acetylated-alpha-linked acidic dipeptidase I) (NAALADase I) (Prostate-specific membrane antigen homolog) (Pteroylpoly-gamma-glutamate carboxypeptidase) Rattus norvegicus (Rat) C-terminal protein deglutamylation [GO:0035609]; folic acid-containing compound metabolic process [GO:0006760]; positive regulation of apoptotic process [GO:0043065]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508] GO:0004180; GO:0004181; GO:0005886; GO:0006508; GO:0006760; GO:0008233; GO:0009986; GO:0016020; GO:0016805; GO:0030163; GO:0035609; GO:0043065; GO:0046872; GO:1904492; GO:1904493 45183 XM_044308576.1 295 281 162 293 306 Q4GZT4 0 Broad substrate specificity ATP-binding cassette transporter ABCG2 (EC 7.6.2.2) (ATP-binding cassette sub-family G member 2) (Urate exporter) (CD antigen CD338) Bos taurus (Bovine) biotin transport [GO:0015878]; lipid transport [GO:0006869]; renal urate salt excretion [GO:0097744]; riboflavin transport [GO:0032218]; transmembrane transport [GO:0055085] GO:0005524; GO:0005886; GO:0006869; GO:0008559; GO:0015143; GO:0015225; GO:0015562; GO:0015878; GO:0016020; GO:0016324; GO:0031526; GO:0031966; GO:0032217; GO:0032218; GO:0042626; GO:0045121; GO:0055085; GO:0097744 45184 XM_044326383.1 5 7 6 25 96 NA NA NA NA NA NA 45185 XM_044318126.1 770 181 455 436 716 E9Q236 0 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 45186 XR_006395746.1 29 0 4 15 132 NA NA NA NA NA NA 45187 XR_003825443.2 2 0 16 0 5 Q9WVH8 1.59e-28 Fibulin-5 (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Embryonic vascular EGF repeat-containing protein) (EVEC) Rattus norvegicus (Rat) cell adhesion [GO:0007155]; elastic fiber assembly [GO:0048251]; extracellular matrix organization [GO:0030198]; intramembranous bone growth [GO:0098867]; negative regulation of angiogenesis [GO:0016525]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to cell surface [GO:0034394]; regulation of cell growth [GO:0001558]; regulation of removal of superoxide radicals [GO:2000121]; secretion [GO:0046903] GO:0000122; GO:0001558; GO:0005178; GO:0005509; GO:0005615; GO:0007155; GO:0008022; GO:0016525; GO:0030198; GO:0033690; GO:0034394; GO:0042803; GO:0045944; GO:0046903; GO:0048251; GO:0062023; GO:0098867; GO:2000121 45188 XM_044316949.1 0 42 0 59 0 G3M4F8 1.07e-45 Octopamine receptor beta-2R (CsOA2B2) Chilo suppressalis (Asiatic rice borer moth) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cellular response to amine stimulus [GO:0071418]; octopamine signaling pathway [GO:0071927]; tyramine signaling pathway [GO:0071928] GO:0004989; GO:0005886; GO:0007189; GO:0008226; GO:0016020; GO:0071418; GO:0071927; GO:0071928 45189 XM_044321126.1 221 71 297 199 154 Q96DM1 7.49e-55 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 45190 XM_044321126.1 221 71 297 199 154 Q96DM1 7.49e-55 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 45191 XM_029333589.2 25 17 28 12 30 NA NA NA NA NA NA 45192 XM_029351372.2 7798 6170 4370 6100 5542 Q9W6I0 2.01e-47 Ubiquinol-cytochrome-c reductase complex assembly factor 1 (Basic FGF-repressed Zic-binding protein homolog) (Ubiquinol-cytochrome c reductase complex chaperone CBP3 homolog) (Zic3-binding protein) Xenopus laevis (African clawed frog) mitochondrial respiratory chain complex III assembly [GO:0034551] GO:0005743; GO:0034551 45193 XM_029355379.2 34 59 24 229 108 NA NA NA NA NA NA 45194 XM_029334729.2 786 1268 1283 1296 1446 Q9C0E8 1.05e-67 Endoplasmic reticulum junction formation protein lunapark (ER junction formation factor lunapark) Homo sapiens (Human) blood coagulation [GO:0007596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum tubular network maintenance [GO:0071788]; endoplasmic reticulum tubular network organization [GO:0071786]; limb development [GO:0060173]; positive regulation of endoplasmic reticulum tubular network organization [GO:1903373]; regulation of chondrocyte differentiation [GO:0032330] GO:0005654; GO:0005783; GO:0005789; GO:0007029; GO:0007596; GO:0016020; GO:0032330; GO:0035115; GO:0042733; GO:0042802; GO:0046872; GO:0060173; GO:0071782; GO:0071786; GO:0071788; GO:0098826; GO:1903373 45195 XM_044320483.1 0 0 301 0 120 P16092 2.77e-97 Fibroblast growth factor receptor 1 (FGFR-1) (bFGF-R-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (MFR) (Proto-oncogene c-Fgr) (CD antigen CD331) Mus musculus (Mouse) angiogenesis [GO:0001525]; auditory receptor cell development [GO:0060117]; blood vessel morphogenesis [GO:0048514]; brain development [GO:0007420]; branching involved in salivary gland morphogenesis [GO:0060445]; calcium ion homeostasis [GO:0055074]; cardiac muscle cell proliferation [GO:0060038]; cell maturation [GO:0048469]; cell population proliferation [GO:0008283]; cementum mineralization [GO:0071529]; central nervous system neuron development [GO:0021954]; chondrocyte differentiation [GO:0002062]; diphosphate metabolic process [GO:0071344]; ear development [GO:0043583]; embryonic limb morphogenesis [GO:0030326]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; gene expression [GO:0010467]; generation of neurons [GO:0048699]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; lung development [GO:0030324]; lung-associated mesenchyme development [GO:0060484]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell proliferation [GO:0010463]; midbrain development [GO:0030901]; middle ear morphogenesis [GO:0042474]; motogenic signaling involved in postnatal olfactory bulb interneuron migration [GO:0021837]; negative regulation of fibroblast growth factor production [GO:0090272]; negative regulation of gene expression [GO:0010629]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron projection development [GO:0031175]; orbitofrontal cortex development [GO:0021769]; organ induction [GO:0001759]; outer ear morphogenesis [GO:0042473]; paraxial mesoderm development [GO:0048339]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of hepatic stellate cell activation [GO:2000491]; positive regulation of inflammatory response [GO:0050729]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway [GO:0090080]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of mitotic cell cycle DNA replication [GO:1903465]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neuron projection development [GO:0010976]; positive regulation of parathyroid hormone secretion [GO:2000830]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; protein autophosphorylation [GO:0046777]; regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling [GO:0060665]; regulation of cell population proliferation [GO:0042127]; regulation of epithelial cell proliferation [GO:0050678]; regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001239]; regulation of gene expression [GO:0010468]; regulation of lateral mesodermal cell fate specification [GO:0048378]; regulation of phosphate transport [GO:0010966]; regulation of phosphorus metabolic process [GO:0051174]; regulation of sensory perception of pain [GO:0051930]; regulation of stem cell proliferation [GO:0072091]; response to sodium phosphate [GO:1904383]; salivary gland morphogenesis [GO:0007435]; sensory perception of sound [GO:0007605]; stem cell differentiation [GO:0048863]; stem cell population maintenance [GO:0019827]; stem cell proliferation [GO:0072089]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; vasculogenesis involved in coronary vascular morphogenesis [GO:0060979]; ventricular zone neuroblast division [GO:0021847]; vitamin D3 metabolic process [GO:0070640] GO:0000122; GO:0001525; GO:0001657; GO:0001701; GO:0001759; GO:0001837; GO:0002053; GO:0002062; GO:0004713; GO:0004714; GO:0005007; GO:0005102; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0007169; GO:0007420; GO:0007435; GO:0007605; GO:0008201; GO:0008283; GO:0008284; GO:0008543; GO:0010463; GO:0010467; GO:0010468; GO:0010629; GO:0010763; GO:0010863; GO:0010966; GO:0010976; GO:0017134; GO:0018108; GO:0019827; GO:0021769; GO:0021837; GO:0021847; GO:0021954; GO:0030324; GO:0030326; GO:0030901; GO:0031175; GO:0031410; GO:0033674; GO:0035607; GO:0042127; GO:0042169; GO:0042472; GO:0042473; GO:0042474; GO:0042802; GO:0042803; GO:0043235; GO:0043406; GO:0043410; GO:0043536; GO:0043583; GO:0044877; GO:0045597; GO:0045666; GO:0045668; GO:0045787; GO:0045944; GO:0046777; GO:0048339; GO:0048378; GO:0048469; GO:0048471; GO:0048514; GO:0048699; GO:0048762; GO:0048863; GO:0050678; GO:0050729; GO:0050839; GO:0051174; GO:0051897; GO:0051930; GO:0055074; GO:0060038; GO:0060045; GO:0060117; GO:0060445; GO:0060484; GO:0060665; GO:0060979; GO:0070640; GO:0071344; GO:0071529; GO:0072089; GO:0072091; GO:0090080; GO:0090272; GO:0090722; GO:1903465; GO:1904383; GO:1905564; GO:2000491; GO:2000546; GO:2000648; GO:2000830; GO:2001239 45196 XM_044308233.1 666 544 381 600 736 O75943 1.98e-137 Cell cycle checkpoint protein RAD17 (hRad17) (RF-C/activator 1 homolog) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; DNA damage checkpoint signaling [GO:0000077]; DNA repair [GO:0006281]; DNA replication checkpoint signaling [GO:0000076]; mitotic DNA replication checkpoint signaling [GO:0033314]; mitotic intra-S DNA damage checkpoint signaling [GO:0031573]; negative regulation of DNA replication [GO:0008156]; regulation of phosphorylation [GO:0042325] GO:0000076; GO:0000077; GO:0003682; GO:0003689; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0006281; GO:0006974; GO:0008156; GO:0031389; GO:0031573; GO:0033314; GO:0042325 45197 XM_044315650.1 6 0 3 2 13 Q08C72 7.31e-44 Pre-mRNA-splicing factor CWC22 homolog (Nucampholin homolog) Danio rerio (Zebrafish) (Brachydanio rerio) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0003723; GO:0005634; GO:0005681; GO:0016607; GO:0071005; GO:0071006; GO:0071007; GO:0071013 45198 XM_044324841.1 1526 903 1131 2453 2168 P27393 4.59e-103 Collagen alpha-2(IV) chain Ascaris suum (Pig roundworm) (Ascaris lumbricoides) anatomical structure development [GO:0048856] GO:0005201; GO:0005576; GO:0005581; GO:0005604; GO:0048856 45199 XM_044324841.1 1526 903 1131 2453 2168 P27393 1.03e-23 Collagen alpha-2(IV) chain Ascaris suum (Pig roundworm) (Ascaris lumbricoides) anatomical structure development [GO:0048856] GO:0005201; GO:0005576; GO:0005581; GO:0005604; GO:0048856 45200 XM_029353170.2 1876 2341 1089 2518 1357 NA NA NA NA NA NA 45201 XM_029340383.2 243 314 229 327 460 Q8IYH5 5.09e-88 ZZ-type zinc finger-containing protein 3 Homo sapiens (Human) histone H3 acetylation [GO:0043966]; histone H3-K14 acetylation [GO:0044154]; histone H4 acetylation [GO:0043967]; regulation of cell cycle [GO:0051726]; regulation of cell division [GO:0051302]; regulation of DNA-templated transcription [GO:0006355]; regulation of embryonic development [GO:0045995]; regulation of histone deacetylation [GO:0031063]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tubulin deacetylation [GO:0090043] GO:0003677; GO:0005654; GO:0005730; GO:0006355; GO:0006357; GO:0008270; GO:0031063; GO:0035064; GO:0043966; GO:0043967; GO:0044154; GO:0045995; GO:0051302; GO:0051726; GO:0070577; GO:0072686; GO:0090043; GO:0140672 45202 XM_044325246.1 790 4579 1732 2765 1521 Q641M3 1.75e-29 Transmembrane protein 18 Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0003677; GO:0031965 45203 XM_029335448.2 366 301 158 453 375 NA NA NA NA NA NA 45204 XM_044321414.1 66 66 33 44 79 NA NA NA NA NA NA 45205 XM_029332598.2 1456 3053 1221 2079 1698 NA NA NA NA NA NA 45206 XM_029339403.2 1470 2281 964 1720 1420 Q90YH9 4.15e-102 Testin Gallus gallus (Chicken) negative regulation of cell population proliferation [GO:0008285] GO:0005737; GO:0005829; GO:0005886; GO:0005925; GO:0008270; GO:0008285; GO:0032991 45207 XR_006393779.1 2 1 12 2 23 NA NA NA NA NA NA 45208 XM_044307612.1 32 50 37 20 0 NA NA NA NA NA NA 45209 XM_029351906.2 3472 1131 1215 1611 1545 Q6NRH1 4.96e-149 DDB1- and CUL4-associated factor 8 (WD repeat-containing protein 42A) Xenopus laevis (African clawed frog) NA GO:0005634; GO:0005737 45210 XR_006393688.1 64 0 133 36 140 Q9JHW0 2.66e-119 Proteasome subunit beta type-7 (EC 3.4.25.1) (Macropain chain Z) (Multicatalytic endopeptidase complex chain Z) (Proteasome subunit Z) Rattus norvegicus (Rat) proteasomal protein catabolic process [GO:0010498] GO:0000502; GO:0004175; GO:0004298; GO:0005634; GO:0005737; GO:0005839; GO:0010498; GO:0019774 45211 XM_044328513.1 5654 2756 3180 4938 5071 C3YWU0 0 Alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucoside fucohydrolase) Branchiostoma floridae (Florida lancelet) (Amphioxus) fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139] GO:0004560; GO:0005576; GO:0005764; GO:0006004; GO:0016139 45212 XR_006394351.1 0 0 0 20 0 A3KN83 0 Protein strawberry notch homolog 1 (Monocyte protein 3) (MOP-3) Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355]; regulation of response to stimulus [GO:0048583] GO:0005634; GO:0006355; GO:0031490; GO:0042393; GO:0048583 45213 XM_044307043.1 68 35 54 21 30 Q7RTR2 1.27e-49 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 45214 XM_044307043.1 68 35 54 21 30 Q7RTR2 4.99e-49 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 45215 XM_044307043.1 68 35 54 21 30 Q7RTR2 8.27e-46 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 45216 XM_044307043.1 68 35 54 21 30 Q7RTR2 3.54e-23 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 45217 XM_044307043.1 68 35 54 21 30 Q7RTR2 9.52e-22 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 45218 XM_029343217.2 3652 891 1344 2213 2176 NA NA NA NA NA NA 45219 XM_044316393.1 43 33 25 15 90 NA NA NA NA NA NA 45220 XR_006394050.1 0 0 0 0 27 NA NA NA NA NA NA 45221 XM_044318494.1 21 57 74 24 48 NA NA NA NA NA NA 45222 XM_044318607.1 99 39 24 87 72 NA NA NA NA NA NA 45223 XM_029333016.2 3448 2753 2456 4266 6293 Q90384 5.91e-101 Peroxiredoxin (EC 1.11.1.24) (Animal blastomere protein, 25 kDa) (ABP-25) (Thioredoxin peroxidase) (Thioredoxin-dependent peroxide reductase) (Thioredoxin-dependent peroxiredoxin) Cynops pyrrhogaster (Japanese fire-bellied newt) (Molge pyrrhogaster) NA GO:0140824 45224 XM_029326202.2 1346 1576 773 855 1466 NA NA NA NA NA NA 45225 XM_029345475.2 81 131 0 116 168 P49253 1.81e-75 Amine oxidase [flavin-containing] (EC 1.4.3.4) (Monoamine oxidase) (MAO) Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) NA GO:0005741; GO:0008131; GO:0097621 45226 XM_044316001.1 64 7 136 10 221 NA NA NA NA NA NA 45227 XM_029327075.2 5263 7770 3926 5158 5997 A7S4N4 5.4e-88 Probable serine incorporator Nematostella vectensis (Starlet sea anemone) phospholipid biosynthetic process [GO:0008654] GO:0005789; GO:0008654; GO:0016020 45228 XM_029352557.2 0 45 0 0 0 Q28I29 2.02e-51 tRNA-uridine aminocarboxypropyltransferase 1 (EC 2.5.1.25) (DTW domain-containing protein 1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) tRNA modification [GO:0006400] GO:0005634; GO:0006400; GO:0016432 45229 XM_029346360.2 0 0 0 12 48 NA NA NA NA NA NA 45230 XM_029350023.2 508 401 186 429 332 O75808 0 Calpain-15 (EC 3.4.22.-) (Small optic lobes homolog) Homo sapiens (Human) proteolysis [GO:0006508] GO:0004198; GO:0005737; GO:0006508; GO:0046872 45231 XR_003827368.2 1078 784 551 926 1551 NA NA NA NA NA NA 45232 XM_029350620.2 4 3 8 7 5 NA NA NA NA NA NA 45233 XR_006392099.1 129 146 108 147 144 NA NA NA NA NA NA 45234 XM_044326663.1 34 3 23 25 9 NA NA NA NA NA NA 45235 XR_006397299.1 109 59 162 62 232 NA NA NA NA NA NA 45236 XM_029334709.2 256 153 185 218 66 NA NA NA NA NA NA 45237 XM_044306892.1 41 57 0 35 41 Q5SY80 6.07e-32 Cation channel sperm-associated auxiliary subunit epsilon (CatSper-epsilon) (CatSperepsilon) Homo sapiens (Human) flagellated sperm motility [GO:0030317]; sperm capacitation [GO:0048240] GO:0030317; GO:0036128; GO:0048240; GO:0097228 45238 XM_029325317.2 394 273 129 261 237 Q96AQ8 2.48e-35 Mitochondrial calcium uniporter regulator 1 (MCU regulator 1) (Coiled-coil domain-containing protein 90A, mitochondrial) Homo sapiens (Human) calcium import into the mitochondrion [GO:0036444]; calcium ion import [GO:0070509]; mitochondrial calcium ion transmembrane transport [GO:0006851]; positive regulation of mitochondrial calcium ion concentration [GO:0051561] GO:0005739; GO:0005743; GO:0006851; GO:0036444; GO:0051561; GO:0070509 45239 XM_029329873.2 269 120 176 302 449 NA NA NA NA NA NA 45240 XM_029329205.2 1721 1527 1032 1286 1100 Q9R1P4 7.27e-143 Proteasome subunit alpha type-1 (Macropain subunit C2) (Multicatalytic endopeptidase complex subunit C2) (Proteasome component C2) (Proteasome nu chain) Mus musculus (Mouse) immune system process [GO:0002376]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; proteasomal protein catabolic process [GO:0010498]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000502; GO:0001530; GO:0002376; GO:0002862; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0005829; GO:0005839; GO:0006511; GO:0010498; GO:0019773 45241 XR_006393880.1 0 0 12 0 0 NA NA NA NA NA NA 45242 XM_029355892.2 31 10 13 35 0 NA NA NA NA NA NA 45243 XR_003823426.1 18 0 8 0 11 NA NA NA NA NA NA 45244 XM_044319541.1 1346 804 742 1284 1418 Q96PX9 5.76e-104 Pleckstrin homology domain-containing family G member 4B (PH domain-containing family G member 4B) Homo sapiens (Human) regulation of small GTPase mediated signal transduction [GO:0051056] GO:0005085; GO:0005829; GO:0051056 45245 XM_044319541.1 1346 804 742 1284 1418 Q96PX9 4.1e-22 Pleckstrin homology domain-containing family G member 4B (PH domain-containing family G member 4B) Homo sapiens (Human) regulation of small GTPase mediated signal transduction [GO:0051056] GO:0005085; GO:0005829; GO:0051056 45246 XM_044311291.1 18 13 42 10 67 NA NA NA NA NA NA 45247 XM_029335651.2 248 266 58 303 92 F6QEU4 7.3e-57 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 45248 XM_044311455.1 18 15 2 24 7 Q5MD89 1.15e-61 Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) Danio rerio (Zebrafish) (Brachydanio rerio) angiogenesis [GO:0001525]; hematopoietic progenitor cell differentiation [GO:0002244]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; lymphangiogenesis [GO:0001946]; lymphatic endothelial cell differentiation [GO:0060836]; motor neuron axon guidance [GO:0008045]; positive regulation of cell migration [GO:0030335]; positive regulation of kinase activity [GO:0033674]; protein autophosphorylation [GO:0046777]; regulation of MAPK cascade [GO:0043408]; regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030947]; regulation of vascular endothelial growth factor signaling pathway [GO:1900746]; selective angioblast sprouting [GO:0035474]; sprouting angiogenesis [GO:0002040]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculature development [GO:0001944]; venous blood vessel development [GO:0060841]; venous endothelial cell migration involved in lymph vessel development [GO:0060855] GO:0001525; GO:0001944; GO:0001945; GO:0001946; GO:0002040; GO:0002244; GO:0004714; GO:0005021; GO:0005524; GO:0005634; GO:0005737; GO:0005886; GO:0007169; GO:0008045; GO:0030335; GO:0030947; GO:0033674; GO:0035474; GO:0036303; GO:0038084; GO:0042802; GO:0043235; GO:0043408; GO:0046777; GO:0048010; GO:0060836; GO:0060841; GO:0060855; GO:1900746 45249 XM_029358572.2 0 546 510 143 307 Q9R088 2.58e-62 Thymidine kinase 2, mitochondrial (EC 2.7.1.21) (2'-deoxyuridine kinase TK2) (EC 2.7.1.74) (Deoxycytidine kinase TK2) (EC 2.7.1.-) (Mt-TK) Mus musculus (Mouse) deoxycytidine metabolic process [GO:0046092]; deoxyribonucleotide metabolic process [GO:0009262]; DNA biosynthetic process [GO:0071897]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA replication [GO:0006264]; phosphorylation [GO:0016310]; thymidine metabolic process [GO:0046104] GO:0004137; GO:0004797; GO:0005524; GO:0005737; GO:0005739; GO:0005743; GO:0006264; GO:0009262; GO:0016310; GO:0019136; GO:0032042; GO:0046092; GO:0046104; GO:0071897 45250 XR_006391695.1 593 305 252 594 525 Q9NXG6 1.66e-61 Transmembrane prolyl 4-hydroxylase (P4H-TM) (EC 1.14.11.29) (Hypoxia-inducible factor prolyl hydroxylase 4) (HIF-PH4) (HIF-prolyl hydroxylase 4) (HPH-4) Homo sapiens (Human) peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; regulation of erythrocyte differentiation [GO:0045646] GO:0004656; GO:0005506; GO:0005509; GO:0005783; GO:0005789; GO:0016706; GO:0018401; GO:0031418; GO:0045646 45251 XR_006391695.1 593 305 252 594 525 Q9NXG6 1.66e-61 Transmembrane prolyl 4-hydroxylase (P4H-TM) (EC 1.14.11.29) (Hypoxia-inducible factor prolyl hydroxylase 4) (HIF-PH4) (HIF-prolyl hydroxylase 4) (HPH-4) Homo sapiens (Human) peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; regulation of erythrocyte differentiation [GO:0045646] GO:0004656; GO:0005506; GO:0005509; GO:0005783; GO:0005789; GO:0016706; GO:0018401; GO:0031418; GO:0045646 45252 XM_029324469.2 0 0 6 2 19 NA NA NA NA NA NA 45253 XM_029328016.2 1815 1252 848 2501 2259 Q7ZUW2 0 Hypoxia up-regulated protein 1 Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to hypoxia [GO:0071456]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298] GO:0005524; GO:0005788; GO:0034663; GO:0071456; GO:0140662; GO:1903298 45254 XM_029328016.2 1815 1252 848 2501 2259 Q7ZUW2 7.65e-25 Hypoxia up-regulated protein 1 Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to hypoxia [GO:0071456]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298] GO:0005524; GO:0005788; GO:0034663; GO:0071456; GO:0140662; GO:1903298 45255 XM_044319144.1 243 229 80 255 43 NA NA NA NA NA NA 45256 XM_044324820.1 2 0 8 0 60 NA NA NA NA NA NA 45257 XR_003827727.2 101 119 264 512 320 NA NA NA NA NA NA 45258 XM_029347840.2 95 157 0 1 210 Q6GM44 9.68e-115 E3 ubiquitin-protein ligase MARCHF5 (EC 2.3.2.27) (Membrane-associated RING finger protein 5) (Membrane-associated RING-CH protein V) (MARCH-V) (RING-type E3 ubiquitin transferase MARCHF5) Xenopus laevis (African clawed frog) protein autoubiquitination [GO:0051865]; regulation of mitochondrial fission [GO:0090140] GO:0005741; GO:0005783; GO:0005789; GO:0008270; GO:0051865; GO:0061630; GO:0090140 45259 XM_044315610.1 466 66 60 108 159 NA NA NA NA NA NA 45260 XR_006398051.1 313 50 19 0 39 NA NA NA NA NA NA 45261 XR_003825645.2 12 8 1 19 21 NA NA NA NA NA NA 45262 XM_044311770.1 6 7 3 4 94 NA NA NA NA NA NA 45263 XM_044317549.1 11 0 17 0 28 NA NA NA NA NA NA 45264 XM_029347693.2 18 2 0 8 0 NA NA NA NA NA NA 45265 XM_029347920.2 4526 2946 3508 3531 3275 A5WWB0 0 Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.4.19.12) (Deubiquitinating enzyme 46) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) Danio rerio (Zebrafish) (Brachydanio rerio) behavior [GO:0007610]; protein deubiquitination [GO:0016579]; regulation of synaptic transmission, GABAergic [GO:0032228]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004197; GO:0004843; GO:0005634; GO:0005829; GO:0006511; GO:0007610; GO:0016579; GO:0032228; GO:0046872 45266 XR_006396338.1 33 93 11 44 37 NA NA NA NA NA NA 45267 XR_006391345.1 0 0 66 70 0 NA NA NA NA NA NA 45268 XR_006397288.1 51 341 13 20 96 NA NA NA NA NA NA 45269 XR_006395766.1 151 50 74 52 40 NA NA NA NA NA NA 45270 XM_029350112.2 176 86 0 38 87 NA NA NA NA NA NA 45271 XM_044308243.1 1592 2666 950 2074 852 NA NA NA NA NA NA 45272 XM_029349480.2 4260 3681 2369 3638 4453 Q27128 0 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase (PAPS synthase) (PAPS synthetase) (PAPSS) (Sulfurylase kinase) (SK) [Includes: Sulfate adenylyltransferase (EC 2.7.7.4) (ATP-sulfurylase) (Sulfate adenylate transferase) (SAT); Adenylyl-sulfate kinase (EC 2.7.1.25) (3'-phosphoadenosine-5'-phosphosulfate synthase) (APS kinase) (Adenosine-5'-phosphosulfate 3'-phosphotransferase) (Adenylylsulfate 3'-phosphotransferase)] Urechis caupo (Innkeeper worm) (Spoonworm) phosphorylation [GO:0016310]; sulfate assimilation [GO:0000103] GO:0000103; GO:0004020; GO:0004781; GO:0005524; GO:0016310; GO:0016779 45273 XM_029345339.2 213 89 64 61 137 E7FAM5 1.43e-47 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 45274 XR_006396089.1 8 4 1 1 19 NA NA NA NA NA NA 45275 XM_029353522.2 5 0 0 10 28 Q924H0 9.71e-23 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide NPFF receptor) Mus musculus (Mouse) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 45276 XM_044319729.1 83 79 1 22 200 Q9VS29 3.85e-28 Cell adhesion molecule Dscam2 (Down syndrome cell adhesion molecule-like protein Dscam2) Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; dendrite self-avoidance [GO:0070593]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron projection morphogenesis [GO:0048812] GO:0005886; GO:0007156; GO:0007411; GO:0030424; GO:0042802; GO:0048812; GO:0070593; GO:0098632 45277 XM_044319729.1 83 79 1 22 200 Q9VS29 7.56e-21 Cell adhesion molecule Dscam2 (Down syndrome cell adhesion molecule-like protein Dscam2) Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; dendrite self-avoidance [GO:0070593]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron projection morphogenesis [GO:0048812] GO:0005886; GO:0007156; GO:0007411; GO:0030424; GO:0042802; GO:0048812; GO:0070593; GO:0098632 45278 XR_006395412.1 4 4 0 10 5 NA NA NA NA NA NA 45279 XR_006394456.1 16 73 30 36 45 Q64077 1.35e-22 Substance-K receptor (SKR) (NK-2 receptor) (NK-2R) (Neurokinin A receptor) (Tachykinin receptor 2) Cavia porcellus (Guinea pig) positive regulation of flagellated sperm motility [GO:1902093]; regulation of uterine smooth muscle contraction [GO:0070472] GO:0004995; GO:0005886; GO:0061827; GO:0070472; GO:0097225; GO:1902093 45280 XR_006394456.1 16 73 30 36 45 Q64077 1.35e-22 Substance-K receptor (SKR) (NK-2 receptor) (NK-2R) (Neurokinin A receptor) (Tachykinin receptor 2) Cavia porcellus (Guinea pig) positive regulation of flagellated sperm motility [GO:1902093]; regulation of uterine smooth muscle contraction [GO:0070472] GO:0004995; GO:0005886; GO:0061827; GO:0070472; GO:0097225; GO:1902093 45281 XM_044313363.1 4 16 238 11 162 NA NA NA NA NA NA 45282 XM_029334314.2 2124 381 3485 4545 183 NA NA NA NA NA NA 45283 XR_006396629.1 10 0 0 3 0 NA NA NA NA NA NA 45284 XM_044325133.1 234 165 93 64 56 Q8CJG0 0 Protein argonaute-2 (Argonaute2) (mAgo2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (Piwi/argonaute family protein meIF2C2) (Protein slicer) Mus musculus (Mouse) cell differentiation [GO:0030154]; miRNA metabolic process [GO:0010586]; miRNA processing [GO:0035196]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; miRNA-mediated gene silencing by mRNA destabilization [GO:0035279]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; negative regulation of translational initiation [GO:0045947]; positive regulation of angiogenesis [GO:0045766]; positive regulation of gene expression [GO:0010628]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of trophoblast cell migration [GO:1901165]; post-embryonic development [GO:0009791]; pre-miRNA processing [GO:0031054]; RISC complex assembly [GO:0070922]; RNA secondary structure unwinding [GO:0010501]; RNA-mediated gene silencing [GO:0031047]; siRNA processing [GO:0030422]; siRNA-mediated gene silencing by mRNA destabilization [GO:0090625] GO:0000340; GO:0000932; GO:0000993; GO:0001046; GO:0003723; GO:0003725; GO:0003727; GO:0003729; GO:0004521; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0005844; GO:0005845; GO:0008022; GO:0009791; GO:0010501; GO:0010586; GO:0010628; GO:0016442; GO:0030154; GO:0030422; GO:0030425; GO:0031047; GO:0031054; GO:0035196; GO:0035197; GO:0035198; GO:0035278; GO:0035279; GO:0036464; GO:0042985; GO:0045766; GO:0045944; GO:0045947; GO:0046872; GO:0060213; GO:0070062; GO:0070551; GO:0070578; GO:0070922; GO:0090624; GO:0090625; GO:0098808; GO:1900153; GO:1901165; GO:1990904 45285 XM_044318569.1 48 94 59 214 141 Q68F72 8.59e-82 Solute carrier family 15 member 4 Xenopus laevis (African clawed frog) dipeptide import across plasma membrane [GO:0140206]; innate immune response [GO:0045087]; mast cell homeostasis [GO:0033023]; peptidoglycan transport [GO:0015835]; positive regulation of innate immune response [GO:0045089]; positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [GO:0070430]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of toll-like receptor 7 signaling pathway [GO:0034157]; positive regulation of toll-like receptor 8 signaling pathway [GO:0034161]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; protein transport [GO:0015031]; regulation of isotype switching to IgG isotypes [GO:0048302]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424] GO:0005290; GO:0005765; GO:0015031; GO:0015333; GO:0015647; GO:0015835; GO:0031901; GO:0033023; GO:0034157; GO:0034161; GO:0034165; GO:0036020; GO:0045087; GO:0045089; GO:0048302; GO:0070424; GO:0070430; GO:0070434; GO:0071916; GO:0140206 45286 XM_029332167.2 187 123 121 144 138 Q2QGD7 3.52e-83 Zinc finger protein ZXDC (ZXD-like zinc finger protein) Homo sapiens (Human) positive regulation of DNA-templated transcription [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0003712; GO:0003713; GO:0005634; GO:0006357; GO:0030275; GO:0045893; GO:0046872; GO:0070742 45287 XR_006391603.1 47 23 23 16 35 NA NA NA NA NA NA 45288 XR_006392568.1 25 0 2 6 1 Q8CJH3 3.2e-67 Plexin-B1 Mus musculus (Mouse) inhibitory synapse assembly [GO:1904862]; negative regulation of cell adhesion [GO:0007162]; negative regulation of osteoblast proliferation [GO:0033689]; neuron projection morphogenesis [GO:0048812]; ossification involved in bone maturation [GO:0043931]; positive regulation of axonogenesis [GO:0050772]; positive regulation of GTPase activity [GO:0043547]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of cytoskeleton organization [GO:0051493]; regulation of GTPase activity [GO:0043087]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis [GO:1900220] GO:0002116; GO:0005886; GO:0007162; GO:0008360; GO:0014068; GO:0017154; GO:0030334; GO:0032794; GO:0033689; GO:0043087; GO:0043547; GO:0043931; GO:0048812; GO:0050772; GO:0051493; GO:0071526; GO:1900220; GO:1902287; GO:1904862 45289 XR_006392568.1 25 0 2 6 1 Q8CJH3 3.2e-67 Plexin-B1 Mus musculus (Mouse) inhibitory synapse assembly [GO:1904862]; negative regulation of cell adhesion [GO:0007162]; negative regulation of osteoblast proliferation [GO:0033689]; neuron projection morphogenesis [GO:0048812]; ossification involved in bone maturation [GO:0043931]; positive regulation of axonogenesis [GO:0050772]; positive regulation of GTPase activity [GO:0043547]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of cytoskeleton organization [GO:0051493]; regulation of GTPase activity [GO:0043087]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis [GO:1900220] GO:0002116; GO:0005886; GO:0007162; GO:0008360; GO:0014068; GO:0017154; GO:0030334; GO:0032794; GO:0033689; GO:0043087; GO:0043547; GO:0043931; GO:0048812; GO:0050772; GO:0051493; GO:0071526; GO:1900220; GO:1902287; GO:1904862 45290 XR_006392568.1 25 0 2 6 1 Q8CJH3 3.2e-67 Plexin-B1 Mus musculus (Mouse) inhibitory synapse assembly [GO:1904862]; negative regulation of cell adhesion [GO:0007162]; negative regulation of osteoblast proliferation [GO:0033689]; neuron projection morphogenesis [GO:0048812]; ossification involved in bone maturation [GO:0043931]; positive regulation of axonogenesis [GO:0050772]; positive regulation of GTPase activity [GO:0043547]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of cytoskeleton organization [GO:0051493]; regulation of GTPase activity [GO:0043087]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis [GO:1900220] GO:0002116; GO:0005886; GO:0007162; GO:0008360; GO:0014068; GO:0017154; GO:0030334; GO:0032794; GO:0033689; GO:0043087; GO:0043547; GO:0043931; GO:0048812; GO:0050772; GO:0051493; GO:0071526; GO:1900220; GO:1902287; GO:1904862 45291 XM_044325635.1 16 2 0 9 5 P70490 2.3e-41 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 45292 XM_029330697.2 85 41 0 51 10 O61585 0 Katanin p80 WD40 repeat-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin) Strongylocentrotus purpuratus (Purple sea urchin) cell cycle [GO:0007049]; cell division [GO:0051301]; microtubule depolymerization [GO:0007019]; microtubule severing [GO:0051013] GO:0000922; GO:0005737; GO:0005813; GO:0005819; GO:0005874; GO:0007019; GO:0007049; GO:0008017; GO:0008352; GO:0051013; GO:0051301 45293 XM_044309518.1 14 0 12 18 5 NA NA NA NA NA NA 45294 XM_044312896.1 116 10 100 39 67 NA NA NA NA NA NA 45295 XM_029340868.2 801 82 72 78 178 Q96AY4 1.52e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 45296 XM_029340868.2 801 82 72 78 178 Q96AY4 1.42e-67 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 45297 XM_029340868.2 801 82 72 78 178 Q96AY4 4.27e-65 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 45298 XM_029340868.2 801 82 72 78 178 Q96AY4 1.17e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 45299 XM_029340868.2 801 82 72 78 178 Q96AY4 1.12e-53 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 45300 XM_029340868.2 801 82 72 78 178 Q96AY4 4.12e-53 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 45301 XM_029340868.2 801 82 72 78 178 Q96AY4 1.64e-46 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 45302 XM_029340868.2 801 82 72 78 178 Q96AY4 3.58e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 45303 XM_029340868.2 801 82 72 78 178 Q96AY4 1.15e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 45304 XM_044328941.1 931 793 404 671 498 Q505B7 9.92e-49 Protein archease (Protein ZBTB8OS) Mus musculus (Mouse) tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388] GO:0006388; GO:0046872; GO:0072669 45305 XR_006397729.1 107 58 55 141 198 NA NA NA NA NA NA 45306 XM_044323485.1 210 2 0 22 0 B7WFQ1 0 Uncharacterized skeletal organic matrix protein 2 (Uncharacterized SOMP-2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 45307 XM_044308859.1 284 160 223 799 124 Q8WVM7 0 Cohesin subunit SA-1 (SCC3 homolog 1) (Stromal antigen 1) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic sister chromatid cohesion [GO:0034087]; localization [GO:0051179]; mitotic spindle assembly [GO:0090307]; sister chromatid cohesion [GO:0007062] GO:0000775; GO:0000785; GO:0003682; GO:0005634; GO:0005654; GO:0005694; GO:0005829; GO:0007062; GO:0008278; GO:0016363; GO:0016604; GO:0034087; GO:0051179; GO:0051301; GO:0090307; GO:0097431 45308 XM_029333575.2 1228 1107 465 828 1220 Q9R050 3.3e-53 Single-stranded DNA-binding protein 3 (Sequence-specific single-stranded-DNA-binding protein) Rattus norvegicus (Rat) DNA-templated transcription elongation [GO:0006354]; head development [GO:0060322]; head morphogenesis [GO:0060323]; hematopoietic progenitor cell differentiation [GO:0002244]; mesendoderm development [GO:0048382]; midbrain-hindbrain boundary initiation [GO:0021547]; positive regulation of anterior head development [GO:2000744]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; prechordal plate formation [GO:0021501]; protein-containing complex assembly [GO:0065003] GO:0002244; GO:0003697; GO:0003713; GO:0005634; GO:0005667; GO:0006354; GO:0008284; GO:0021501; GO:0021547; GO:0032991; GO:0045893; GO:0045944; GO:0048382; GO:0060322; GO:0060323; GO:0065003; GO:2000744 45309 XM_044325649.1 2 10 16 18 18 Q6DIV6 2.36e-42 Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Solute carrier family 32 member 1) (Vesicular GABA transporter) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) beta-alanine transport [GO:0001762]; gamma-aminobutyric acid import [GO:0051939]; gamma-aminobutyric acid transport [GO:0015812]; glycine transport [GO:0015816]; neurotransmitter transport [GO:0006836] GO:0001762; GO:0006836; GO:0008021; GO:0015185; GO:0015187; GO:0015812; GO:0015816; GO:0030659; GO:0042995; GO:0051939; GO:0098793; GO:0140799; GO:0140800 45310 XR_006393935.1 0 0 26 3 13 NA NA NA NA NA NA 45311 XM_044309672.1 51 49 13 74 105 NA NA NA NA NA NA 45312 XM_044315922.1 0 0 0 0 19 NA NA NA NA NA NA 45313 XR_006391321.1 10 0 18 6 40 NA NA NA NA NA NA 45314 XM_044323840.1 452 242 436 1056 631 B8V7S0 1.2e-65 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 45315 XM_029346484.2 63 7 155 37 15 Q504M2 5.2e-74 NA NA NA NA 45316 XM_044318530.1 0 453 52 572 423 P62296 0 Abnormal spindle-like microcephaly-associated protein homolog Saimiri boliviensis boliviensis (Bolivian squirrel monkey) cell cycle [GO:0007049]; cell division [GO:0051301]; cytoskeleton organization [GO:0007010] GO:0005516; GO:0005634; GO:0005737; GO:0005819; GO:0007010; GO:0007049; GO:0051301 45317 XM_044308600.1 358 41 122 149 818 NA NA NA NA NA NA 45318 XM_044322775.1 187 180 112 172 125 D3YV10 2.78e-79 Coiled-coil domain-containing protein 13 Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; cytoplasmic microtubule organization [GO:0031122]; non-motile cilium assembly [GO:1905515] GO:0005654; GO:0005813; GO:0005829; GO:0006974; GO:0031122; GO:0034451; GO:0042995; GO:1905515 45319 XR_006393679.1 187 706 93 260 140 NA NA NA NA NA NA 45320 XM_044319165.1 5 0 0 39 37 Q28IV8 1.76e-64 Neuroguidin (EIF4E-binding protein) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) regulation of translation [GO:0006417] GO:0005634; GO:0005737; GO:0006417 45321 XM_044318722.1 235 338 128 381 10 NA NA NA NA NA NA 45322 XM_044324708.1 157 19 123 55 611 NA NA NA NA NA NA 45323 XM_044319890.1 28 25 29 48 55 Q9D1Q1 2.02e-21 M-phase phosphoprotein 6 Mus musculus (Mouse) maturation of 5.8S rRNA [GO:0000460] GO:0000176; GO:0000178; GO:0000460; GO:0003723; GO:0005634; GO:0005654; GO:0005730; GO:0005829 45324 XM_044309252.1 81 36 37 80 161 NA NA NA NA NA NA 45325 XR_006392874.1 41 2 25 5 151 NA NA NA NA NA NA 45326 XM_029336459.2 2982 2560 1769 2294 2189 Q6PAX8 6.39e-37 HUWE1-associated protein modifying stress responses (Telomere attrition and p53 response 1 protein) Xenopus laevis (African clawed frog) negative regulation of signal transduction by p53 class mediator [GO:1901797]; regulation of cellular response to stress [GO:0080135] GO:0005634; GO:0005737; GO:0080135; GO:1901797 45327 XM_044307362.1 90 31 132 26 196 Q5DU56 8.21e-51 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 45328 XM_044307362.1 90 31 132 26 196 Q5DU56 1.97e-44 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 45329 XM_044307362.1 90 31 132 26 196 Q5DU56 3.23e-44 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 45330 XM_044307362.1 90 31 132 26 196 Q5DU56 3.15e-43 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 45331 XM_044307362.1 90 31 132 26 196 Q5DU56 3e-40 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 45332 XM_044307362.1 90 31 132 26 196 Q5DU56 1.49e-37 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 45333 XM_044307362.1 90 31 132 26 196 Q5DU56 3.15e-21 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 45334 XM_044313784.1 493 68 155 231 406 NA NA NA NA NA NA 45335 XM_044323357.1 0 0 31 0 0 Q9U6Y6 6.96e-111 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 45336 XM_029341868.2 316 682 290 557 452 Q2TBX4 2e-151 Heat shock 70 kDa protein 13 (Stress-70 protein chaperone microsome-associated 60 kDa protein) Bos taurus (Bovine) cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein refolding [GO:0042026] GO:0005524; GO:0005737; GO:0005739; GO:0005783; GO:0016887; GO:0031072; GO:0034620; GO:0042026; GO:0044183; GO:0051082; GO:0051085; GO:0051787; GO:0140662 45337 XM_029345653.2 19 10 18 3 142 NA NA NA NA NA NA 45338 XM_029345803.2 1997 1622 1315 3382 3358 Q5QNI2 2.37e-29 Sodium/calcium exchanger NCL1 (Na(+)/Ca(2+)-exchange protein NCL1) (OsEFCAX1) (Protein NCX-like 1) (OsNCL1) Oryza sativa subsp. japonica (Rice) calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; sodium ion transport [GO:0006814] GO:0005509; GO:0005774; GO:0005886; GO:0006814; GO:0006874; GO:0015369; GO:0070588 45339 XM_029344326.2 5165 4348 3722 5509 4880 Q91WC7 6.84e-85 NIPA-like protein 2 Mus musculus (Mouse) magnesium ion transport [GO:0015693] GO:0015095; GO:0015693; GO:0016020 45340 XM_044323568.1 72 0 51 37 113 NA NA NA NA NA NA 45341 XR_006393966.1 11 8 30 9 117 NA NA NA NA NA NA 45342 XM_044322869.1 9 15 0 65 37 Q9NZJ4 0 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 45343 XM_044322869.1 9 15 0 65 37 Q9NZJ4 1.12e-41 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 45344 XR_003827331.2 143 231 86 193 150 NA NA NA NA NA NA 45345 XM_044326556.1 5 6 0 0 0 NA NA NA NA NA NA 45346 XM_044316447.1 1 0 7 1 50 Q09575 8.38e-24 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 45347 XR_006393325.1 79 22 20 14 120 NA NA NA NA NA NA 45348 XM_044317872.1 0 27 14 85 14 Q96CG8 4.39e-43 Collagen triple helix repeat-containing protein 1 Homo sapiens (Human) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005576; GO:0005581; GO:0005615; GO:0016477; GO:0016528; GO:0017147; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0062023; GO:0090090; GO:0090103; GO:0090177 45349 XM_044316056.1 13 29 37 0 2 P04323 3.32e-67 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 45350 XR_006397706.1 11 11 2 9 5 NA NA NA NA NA NA 45351 XM_029339134.2 2343 2700 1701 1883 1782 Q08CA1 2.17e-56 GDP-D-glucose phosphorylase 1 (EC 2.7.7.78) Danio rerio (Zebrafish) (Brachydanio rerio) glucose metabolic process [GO:0006006] GO:0000166; GO:0005085; GO:0005737; GO:0006006; GO:0016787; GO:0080048 45352 XM_029339134.2 2343 2700 1701 1883 1782 Q08CA1 2.33e-49 GDP-D-glucose phosphorylase 1 (EC 2.7.7.78) Danio rerio (Zebrafish) (Brachydanio rerio) glucose metabolic process [GO:0006006] GO:0000166; GO:0005085; GO:0005737; GO:0006006; GO:0016787; GO:0080048 45353 XM_029344460.2 0 180 0 0 0 Q8K078 3.57e-102 Solute carrier organic anion transporter family member 4A1 (Organic anion-transporting polypeptide E) (OATP-E) (Sodium-independent organic anion transporter E) (Solute carrier family 21 member 12) Mus musculus (Mouse) sodium-independent organic anion transport [GO:0043252]; thyroid hormone metabolic process [GO:0042403] GO:0005886; GO:0008514; GO:0015132; GO:0015347; GO:0015349; GO:0042403; GO:0043252 45354 XM_044314265.1 0 0 0 594 589 O54781 3.38e-87 SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) (Serine/arginine-rich protein-specific kinase 2) (SR-protein-specific kinase 2) [Cleaved into: SRSF protein kinase 2 N-terminal; SRSF protein kinase 2 C-terminal] Mus musculus (Mouse) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; intracellular signal transduction [GO:0035556]; negative regulation of viral genome replication [GO:0045071]; nuclear speck organization [GO:0035063]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of viral genome replication [GO:0045070]; protein phosphorylation [GO:0006468]; R-loop processing [GO:0062176]; regulation of mRNA processing [GO:0050684]; RNA splicing [GO:0008380]; spliceosomal complex assembly [GO:0000245] GO:0000245; GO:0000287; GO:0000785; GO:0001525; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0006468; GO:0008284; GO:0008380; GO:0010628; GO:0016607; GO:0018105; GO:0030154; GO:0035063; GO:0035556; GO:0043525; GO:0045070; GO:0045071; GO:0045787; GO:0050684; GO:0062176; GO:0071889; GO:0106310 45355 XM_044314265.1 0 0 0 594 589 O54781 1.38e-82 SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) (Serine/arginine-rich protein-specific kinase 2) (SR-protein-specific kinase 2) [Cleaved into: SRSF protein kinase 2 N-terminal; SRSF protein kinase 2 C-terminal] Mus musculus (Mouse) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; intracellular signal transduction [GO:0035556]; negative regulation of viral genome replication [GO:0045071]; nuclear speck organization [GO:0035063]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of viral genome replication [GO:0045070]; protein phosphorylation [GO:0006468]; R-loop processing [GO:0062176]; regulation of mRNA processing [GO:0050684]; RNA splicing [GO:0008380]; spliceosomal complex assembly [GO:0000245] GO:0000245; GO:0000287; GO:0000785; GO:0001525; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0006468; GO:0008284; GO:0008380; GO:0010628; GO:0016607; GO:0018105; GO:0030154; GO:0035063; GO:0035556; GO:0043525; GO:0045070; GO:0045071; GO:0045787; GO:0050684; GO:0062176; GO:0071889; GO:0106310 45356 XM_044320365.1 40 33 42 41 69 NA NA NA NA NA NA 45357 XM_044327377.1 61 26 27 46 50 NA NA NA NA NA NA 45358 XM_029348547.2 255 102 93 106 110 Q9NXK8 4.93e-28 F-box/LRR-repeat protein 12 (F-box and leucine-rich repeat protein 12) (F-box protein FBL12) Homo sapiens (Human) entrainment of circadian clock by photoperiod [GO:0043153]; G2/M transition of mitotic cell cycle [GO:0000086]; protein ubiquitination [GO:0016567]; regulation of cell cycle [GO:0051726]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0000086; GO:0005634; GO:0005829; GO:0016567; GO:0019005; GO:0031146; GO:0043153; GO:0051726 45359 XM_029336236.2 487 383 165 716 528 NA NA NA NA NA NA 45360 XR_006396829.1 170 103 136 112 164 NA NA NA NA NA NA 45361 XR_006395724.1 0 0 0 0 17 NA NA NA NA NA NA 45362 XM_029336652.2 17 0 0 0 0 NA NA NA NA NA NA 45363 XM_044310934.1 7 0 0 0 29 NA NA NA NA NA NA 45364 XM_029332585.2 0 0 0 53 0 A1YF12 3.07e-37 Zinc finger protein 16 Gorilla gorilla gorilla (Western lowland gorilla) cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to sodium dodecyl sulfate [GO:0072707]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell cycle phase transition [GO:1901989]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of kinase activity [GO:0033674]; positive regulation of megakaryocyte differentiation [GO:0045654]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0005654; GO:0005730; GO:0006357; GO:0007049; GO:0008284; GO:0033674; GO:0043066; GO:0045648; GO:0045654; GO:0046872; GO:0051301; GO:0051781; GO:0072707; GO:1901989 45365 XM_029332585.2 0 0 0 53 0 A1YF12 1.53e-28 Zinc finger protein 16 Gorilla gorilla gorilla (Western lowland gorilla) cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to sodium dodecyl sulfate [GO:0072707]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell cycle phase transition [GO:1901989]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of kinase activity [GO:0033674]; positive regulation of megakaryocyte differentiation [GO:0045654]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0005654; GO:0005730; GO:0006357; GO:0007049; GO:0008284; GO:0033674; GO:0043066; GO:0045648; GO:0045654; GO:0046872; GO:0051301; GO:0051781; GO:0072707; GO:1901989 45366 XM_029332585.2 0 0 0 53 0 A1YF12 5.13e-27 Zinc finger protein 16 Gorilla gorilla gorilla (Western lowland gorilla) cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to sodium dodecyl sulfate [GO:0072707]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell cycle phase transition [GO:1901989]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of kinase activity [GO:0033674]; positive regulation of megakaryocyte differentiation [GO:0045654]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0005654; GO:0005730; GO:0006357; GO:0007049; GO:0008284; GO:0033674; GO:0043066; GO:0045648; GO:0045654; GO:0046872; GO:0051301; GO:0051781; GO:0072707; GO:1901989 45367 XM_029332585.2 0 0 0 53 0 A1YF12 7.75e-27 Zinc finger protein 16 Gorilla gorilla gorilla (Western lowland gorilla) cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to sodium dodecyl sulfate [GO:0072707]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell cycle phase transition [GO:1901989]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of kinase activity [GO:0033674]; positive regulation of megakaryocyte differentiation [GO:0045654]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0005654; GO:0005730; GO:0006357; GO:0007049; GO:0008284; GO:0033674; GO:0043066; GO:0045648; GO:0045654; GO:0046872; GO:0051301; GO:0051781; GO:0072707; GO:1901989 45368 XM_029332585.2 0 0 0 53 0 A1YF12 2.42e-26 Zinc finger protein 16 Gorilla gorilla gorilla (Western lowland gorilla) cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to sodium dodecyl sulfate [GO:0072707]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell cycle phase transition [GO:1901989]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of kinase activity [GO:0033674]; positive regulation of megakaryocyte differentiation [GO:0045654]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0005654; GO:0005730; GO:0006357; GO:0007049; GO:0008284; GO:0033674; GO:0043066; GO:0045648; GO:0045654; GO:0046872; GO:0051301; GO:0051781; GO:0072707; GO:1901989 45369 XM_029332585.2 0 0 0 53 0 A1YF12 9.24e-26 Zinc finger protein 16 Gorilla gorilla gorilla (Western lowland gorilla) cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to sodium dodecyl sulfate [GO:0072707]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell cycle phase transition [GO:1901989]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of kinase activity [GO:0033674]; positive regulation of megakaryocyte differentiation [GO:0045654]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0005654; GO:0005730; GO:0006357; GO:0007049; GO:0008284; GO:0033674; GO:0043066; GO:0045648; GO:0045654; GO:0046872; GO:0051301; GO:0051781; GO:0072707; GO:1901989 45370 XM_029339413.2 27 51 59 60 98 Q8C1Z8 2.05e-69 tRNA methyltransferase 10 homolog A (EC 2.1.1.221) (RNA (guanine-9-)-methyltransferase domain-containing protein 2) (tRNA (guanine(9)-N(1))-methyltransferase TRMT10A) Mus musculus (Mouse) magnesium ion homeostasis [GO:0010960]; tRNA methylation [GO:0030488]; tRNA N1-guanine methylation [GO:0002939] GO:0000049; GO:0002939; GO:0005634; GO:0005654; GO:0005730; GO:0005829; GO:0009019; GO:0010960; GO:0015629; GO:0030488; GO:0052905 45371 XM_044308633.1 7 0 0 0 53 NA NA NA NA NA NA 45372 XM_029347575.2 3314 2466 1447 1220 1471 Q9CQ61 1.82e-79 Protein unc-50 homolog (Periodontal ligament-specific protein 22) (PDLs22) Mus musculus (Mouse) protein localization to cell surface [GO:0034394] GO:0000139; GO:0003723; GO:0005637; GO:0005794; GO:0034394 45373 XR_006396662.1 8 0 4 14 0 NA NA NA NA NA NA 45374 XM_044319872.1 0 6 26 17 127 NA NA NA NA NA NA 45375 XM_044318689.1 426 672 713 422 631 P42695 0 Condensin-2 complex subunit D3 (Non-SMC condensin II complex subunit D3) (hCAP-D3) Homo sapiens (Human) cell division [GO:0051301]; meiotic chromosome condensation [GO:0010032]; mitotic chromosome condensation [GO:0007076]; positive regulation of chromosome condensation [GO:1905821]; positive regulation of chromosome segregation [GO:0051984]; positive regulation of chromosome separation [GO:1905820] GO:0000779; GO:0000794; GO:0000796; GO:0005654; GO:0005721; GO:0007076; GO:0010032; GO:0016020; GO:0035064; GO:0042393; GO:0051301; GO:0051984; GO:1905820; GO:1905821 45376 XM_029354493.2 606 628 343 656 556 NA NA NA NA NA NA 45377 XM_029349582.2 40914 29388 13273 21572 9643 NA NA NA NA NA NA 45378 XM_029327777.2 404 238 98 251 339 Q28I85 0 POC1 centriolar protein homolog A (Pat-interacting protein 2) (Pix2) (xPix2) (WD repeat-containing protein 51A) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737; GO:0005856 45379 XM_044325155.1 1060 1043 645 833 639 Q6DED0 1.01e-98 Translocating chain-associated membrane protein 1-like 1 Xenopus laevis (African clawed frog) SRP-dependent cotranslational protein targeting to membrane, translocation [GO:0006616] GO:0005789; GO:0006616 45380 XM_029341031.2 7 5 9 28 30 NA NA NA NA NA NA 45381 XR_006393606.1 17 0 0 0 23 NA NA NA NA NA NA 45382 XR_006392222.1 14 4 0 5 4 NA NA NA NA NA NA 45383 XM_029352990.2 328 204 210 123 136 NA NA NA NA NA NA 45384 XR_006392346.1 18 57 33 40 9 Q99570 7.02e-27 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 45385 XR_006392346.1 18 57 33 40 9 Q99570 7.02e-27 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 45386 XR_006392346.1 18 57 33 40 9 Q99570 7.02e-27 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 45387 XR_006392346.1 18 57 33 40 9 Q99570 7.02e-27 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 45388 XM_029357724.2 218 156 103 250 179 NA NA NA NA NA NA 45389 XM_044314725.1 0 0 0 0 160 NA NA NA NA NA NA 45390 XM_044323921.1 728 333 296 408 375 Q9VL06 5.45e-21 E3 ubiquitin-protein ligase Ufd4 (EC 2.3.2.26) (Ubiquitin fusion-degradation 4-like) Drosophila melanogaster (Fruit fly) anatomical structure development [GO:0048856]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000209; GO:0005634; GO:0006511; GO:0016607; GO:0032436; GO:0043161; GO:0046872; GO:0048856; GO:0061630; GO:0070373; GO:0070534 45391 XM_029334976.2 2950 2960 2137 2835 2672 Q99KR6 1.05e-34 E3 ubiquitin-protein ligase RNF34 (EC 2.3.2.27) (Phafin-1) (RING finger protein 34) (RING-type E3 ubiquitin transferase RNF34) Mus musculus (Mouse) apoptotic process [GO:0006915]; cellular response to cold [GO:0070417]; negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis [GO:2001271]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of signal transduction by p53 class mediator [GO:1901797]; nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [GO:0035872]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination [GO:0016567]; regulation of oxygen metabolic process [GO:2000374]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0002039; GO:0004842; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0006511; GO:0006915; GO:0012505; GO:0016567; GO:0016604; GO:0016607; GO:0031625; GO:0035872; GO:0043161; GO:0046872; GO:0061630; GO:0070417; GO:0070936; GO:1901797; GO:1901981; GO:1902042; GO:2000374; GO:2001271 45392 XM_044328627.1 2361 1571 1534 1787 1645 O88529 7.23e-141 Basic helix-loop-helix ARNT-like protein 1 (Aryl hydrocarbon receptor nuclear translocator-like protein 1) (Brain and muscle ARNT-like 1) Mesocricetus auratus (Golden hamster) circadian regulation of gene expression [GO:0032922]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of glucocorticoid receptor signaling pathway [GO:2000323]; negative regulation of TOR signaling [GO:0032007]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of protein acetylation [GO:1901985]; positive regulation of skeletal muscle cell differentiation [GO:2001016]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of cell cycle [GO:0051726]; regulation of cellular senescence [GO:2000772]; regulation of DNA-templated transcription [GO:0006355]; regulation of hair cycle [GO:0042634]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of type B pancreatic cell development [GO:2000074]; response to redox state [GO:0051775]; spermatogenesis [GO:0007283] GO:0000976; GO:0000978; GO:0003677; GO:0003700; GO:0005634; GO:0005667; GO:0006355; GO:0007283; GO:0016605; GO:0017162; GO:0032007; GO:0032922; GO:0033391; GO:0042634; GO:0042753; GO:0043161; GO:0043565; GO:0045599; GO:0045892; GO:0045893; GO:0045944; GO:0046983; GO:0050767; GO:0050796; GO:0051726; GO:0051775; GO:0051879; GO:0070888; GO:0090263; GO:0090403; GO:1901985; GO:1990513; GO:2000074; GO:2000323; GO:2000772; GO:2001016 45393 XM_044325231.1 552 476 223 326 164 Q9JHB4 6.44e-75 WD repeat-containing protein 31 (Spermatid WD repeat-containing protein) (spWD) Mus musculus (Mouse) NA NA 45394 XR_006395365.1 151 52 349 238 361 O54991 1.2e-35 Contactin-associated protein 1 (Caspr) (Caspr1) (MHDNIV) (NCP1) (Neurexin IV) (Neurexin-4) (Paranodin) Mus musculus (Mouse) axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cytoskeleton organization [GO:0007010]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process [GO:0050905]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuronal action potential propagation [GO:0019227]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; postsynaptic density organization [GO:0097106]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; regulation of synapse maturation [GO:0090128] GO:0002175; GO:0005886; GO:0005918; GO:0007005; GO:0007010; GO:0007155; GO:0007409; GO:0016020; GO:0017124; GO:0019227; GO:0022010; GO:0022011; GO:0030424; GO:0030913; GO:0031175; GO:0033010; GO:0033270; GO:0042552; GO:0043209; GO:0048786; GO:0048812; GO:0050884; GO:0050885; GO:0050905; GO:0071205; GO:0090128; GO:0097106; GO:0098529; GO:0098978; GO:1990227 45395 XM_044324578.1 83 114 110 122 68 NA NA NA NA NA NA 45396 XM_029346330.2 8 14 4 4 50 NA NA NA NA NA NA 45397 XM_044313444.1 146 87 16 62 26 NA NA NA NA NA NA 45398 XM_044326970.1 4 0 1 2 9 Q8BUZ3 3.49e-28 Tigger transposable element-derived protein 4 Mus musculus (Mouse) NA GO:0003677; GO:0005634 45399 XM_044328257.1 229 0 122 96 821 P33198 0 Isocitrate dehydrogenase [NADP], mitochondrial (IDH) (EC 1.1.1.42) (ICD-M) (IDP) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase) Sus scrofa (Pig) 2-oxoglutarate metabolic process [GO:0006103]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; NADP metabolic process [GO:0006739]; tricarboxylic acid cycle [GO:0006099] GO:0000287; GO:0004450; GO:0005739; GO:0006097; GO:0006099; GO:0006102; GO:0006103; GO:0006739; GO:0051287 45400 XR_006395339.1 69 134 19 86 43 O42430 3.21e-65 Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) Limanda limanda (Common dab) (Pleuronectes limanda) NA GO:0005506; GO:0005789; GO:0020037; GO:0070330 45401 XR_006395339.1 69 134 19 86 43 O42430 3.21e-65 Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) Limanda limanda (Common dab) (Pleuronectes limanda) NA GO:0005506; GO:0005789; GO:0020037; GO:0070330 45402 XR_006395339.1 69 134 19 86 43 O42430 3.21e-65 Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) Limanda limanda (Common dab) (Pleuronectes limanda) NA GO:0005506; GO:0005789; GO:0020037; GO:0070330 45403 XR_006395339.1 69 134 19 86 43 O42430 3.21e-65 Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) Limanda limanda (Common dab) (Pleuronectes limanda) NA GO:0005506; GO:0005789; GO:0020037; GO:0070330 45404 XM_044307801.1 113 42 0 4 67 NA NA NA NA NA NA 45405 XM_029347909.2 25 2 22 44 85 NA NA NA NA NA NA 45406 XM_029330575.2 0 0 0 68 99 NA NA NA NA NA NA 45407 XM_029342908.2 0 4 4 4 19 Q17RP2 1.52e-66 Tigger transposable element-derived protein 6 Homo sapiens (Human) NA GO:0003677; GO:0005634 45408 XM_044307176.1 321 140 177 215 598 Q6NT99 2.92e-36 Dual specificity protein phosphatase 23 (EC 3.1.3.16) (EC 3.1.3.48) (Low molecular mass dual specificity phosphatase 3) (LDP-3) Mus musculus (Mouse) dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470] GO:0004725; GO:0005654; GO:0005737; GO:0005829; GO:0006470; GO:0008138; GO:0016311; GO:0016791; GO:0017018 45409 XM_029356236.2 24 0 0 0 0 Q9JIM4 2.89e-50 Dual specificity protein phosphatase 12 (EC 3.1.3.16) (EC 3.1.3.48) (Glucokinase-associated dual specificity phosphatase) (GKAP) Rattus norvegicus (Rat) dephosphorylation [GO:0016311]; positive regulation of glucokinase activity [GO:0033133]; protein dephosphorylation [GO:0006470] GO:0004721; GO:0004725; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006470; GO:0008138; GO:0008270; GO:0016311; GO:0016791; GO:0017018; GO:0019900; GO:0033133 45410 XM_029346648.2 4 0 0 48 4 NA NA NA NA NA NA 45411 XR_003825064.2 19 0 0 33 0 NA NA NA NA NA NA 45412 XM_044308528.1 8 1 2 0 10 NA NA NA NA NA NA 45413 XR_003826696.2 1 0 0 4 24 NA NA NA NA NA NA 45414 XM_044319018.1 0 44 49 0 85 Q09328 4.31e-146 Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (EC 2.4.1.155) (Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase V) (GlcNAc-T V) (GNT-V) (Mannoside acetylglucosaminyltransferase 5) (N-acetylglucosaminyl-transferase V) [Cleaved into: Secreted alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (Secreted beta-1,6-N-acetylglucosaminyltransferase V) (Secreted GNT-V)] Homo sapiens (Human) negative regulation of protein tyrosine phosphatase activity [GO:1903614]; positive regulation of cell migration [GO:0030335]; positive regulation of receptor signaling pathway via STAT [GO:1904894]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279]; viral protein processing [GO:0019082] GO:0000139; GO:0004864; GO:0005794; GO:0006487; GO:0016020; GO:0018279; GO:0019082; GO:0030144; GO:0030145; GO:0030335; GO:0070062; GO:1903614; GO:1904894 45415 XM_029356333.2 3 8 16 24 9 NA NA NA NA NA NA 45416 XM_029326793.2 63 0 0 1 1 NA NA NA NA NA NA 45417 XM_029325805.2 144 80 90 111 196 A7SKJ3 0 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 (Diphthamide biosynthesis protein 2) (Diphtheria toxin resistance protein 2) (S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2) Nematostella vectensis (Starlet sea anemone) peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183] GO:0017183; GO:0032991; GO:0046872; GO:0051539; GO:0090560 45418 XM_029331504.2 283 189 169 212 214 Q68FF9 1.89e-89 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (EC 1.3.1.22) (SR type 1) (Steroid 5-alpha-reductase 1) (S5AR 1) Mus musculus (Mouse) androgen biosynthetic process [GO:0006702]; androgen catabolic process [GO:0006710]; androgen metabolic process [GO:0008209]; cell differentiation [GO:0030154]; progesterone metabolic process [GO:0042448]; response to xenobiotic stimulus [GO:0009410]; sex differentiation [GO:0007548]; steroid biosynthetic process [GO:0006694] GO:0003865; GO:0005737; GO:0005789; GO:0006694; GO:0006702; GO:0006710; GO:0007548; GO:0008209; GO:0009410; GO:0016491; GO:0030154; GO:0033218; GO:0042448; GO:0043025; GO:0043209; GO:0043231; GO:0047751; GO:0048471; GO:0050213; GO:0070402; GO:0070852 45419 XR_006392919.1 41 2 25 5 151 NA NA NA NA NA NA 45420 XM_044313086.1 143 93 46 348 128 NA NA NA NA NA NA 45421 XM_029345770.2 611 436 404 839 961 Q7TQE6 4.61e-164 Macoilin (Brain-specific adapter protein C61) (Macoilin-1) (Transmembrane protein 57) Mus musculus (Mouse) brain development [GO:0007420]; chemotaxis [GO:0006935]; neuronal signal transduction [GO:0023041] GO:0005634; GO:0006935; GO:0007420; GO:0008017; GO:0023041; GO:0030424; GO:0030867; GO:0031965; GO:0043005; GO:0044306; GO:0045202 45422 XR_006396088.1 0 0 0 0 37 NA NA NA NA NA NA 45423 XM_044324020.1 0 0 6 8 35 NA NA NA NA NA NA 45424 XM_044322551.1 9 0 10 0 0 NA NA NA NA NA NA 45425 XR_003828319.2 5 0 0 2 9 NA NA NA NA NA NA 45426 XR_003825858.2 221 224 76 235 516 NA NA NA NA NA NA 45427 XM_044308618.1 240 0 58 74 0 NA NA NA NA NA NA 45428 XM_044318658.1 0 0 0 0 39 O75899 1.05e-71 Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51) (HG20) Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway [GO:0007186]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; neuron-glial cell signaling [GO:0150099]; synaptic transmission, GABAergic [GO:0051932] GO:0004888; GO:0004965; GO:0005737; GO:0005886; GO:0007186; GO:0007193; GO:0007194; GO:0007214; GO:0007268; GO:0038039; GO:0043005; GO:0045211; GO:0046982; GO:0051932; GO:0150099; GO:1902710; GO:1902712 45429 XR_003827967.2 0 3 1 6 8 NA NA NA NA NA NA 45430 XM_029345702.2 1 0 11 0 0 NA NA NA NA NA NA 45431 XR_003827288.2 44 26 69 62 106 NA NA NA NA NA NA 45432 XM_044309488.1 0 0 0 18 1 NA NA NA NA NA NA 45433 XM_029332282.2 552 355 311 695 657 NA NA NA NA NA NA 45434 XM_029336158.2 131 30 31 49 110 NA NA NA NA NA NA 45435 XM_029333595.2 8 5 12 15 0 NA NA NA NA NA NA 45436 XM_029346608.2 23 20 27 15 37 Q9NQR9 3.71e-63 Glucose-6-phosphatase 2 (G-6-Pase 2) (G6Pase 2) (EC 3.1.3.9) (Islet-specific glucose-6-phosphatase catalytic subunit-related protein) Homo sapiens (Human) gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; regulation of insulin secretion [GO:0050796] GO:0004346; GO:0005789; GO:0006094; GO:0016020; GO:0042593; GO:0050796; GO:0051156 45437 XM_029339223.2 3 0 5 0 73 NA NA NA NA NA NA 45438 XM_029327162.2 2824 3789 1058 1882 1478 P56616 3.62e-51 Ubiquitin-conjugating enzyme E2 C (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme C) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme C) (UBC-X) (Ubiquitin carrier protein C) (Ubiquitin-protein ligase C) Xenopus laevis (African clawed frog) anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; exit from mitosis [GO:0010458]; free ubiquitin chain polymerization [GO:0010994]; protein K11-linked ubiquitination [GO:0070979]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0005524; GO:0005680; GO:0006511; GO:0010458; GO:0010994; GO:0031145; GO:0051301; GO:0061631; GO:0070979 45439 XM_044318482.1 5 32 34 33 231 P48040 1.8e-28 Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor) Ovis aries (Sheep) NA GO:0005886; GO:0008502 45440 XM_044313296.1 1910 242 618 963 1160 F1NWE3 1.52e-141 Receptor-type tyrosine-protein phosphatase S (R-PTP-S) (EC 3.1.3.48) (Chick receptor tyrosine phosphatase alpha) (CRYP alpha) (CRYPalpha) Gallus gallus (Chicken) negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; synaptic membrane adhesion [GO:0099560] GO:0004725; GO:0005886; GO:0006470; GO:0008201; GO:0030424; GO:0030426; GO:0030517; GO:0030672; GO:0035335; GO:0042803; GO:0043204; GO:0043395; GO:0048671; GO:0048681; GO:0061000; GO:0098839; GO:0099560 45441 XM_044318146.1 122 32 56 130 208 Q08DG4 6.76e-26 F-box/LRR-repeat protein 8 (F-box and leucine-rich repeat protein 8) Bos taurus (Bovine) entrainment of circadian clock by photoperiod [GO:0043153]; G2/M transition of mitotic cell cycle [GO:0000086]; regulation of cell cycle [GO:0051726]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0000086; GO:0005634; GO:0005829; GO:0019005; GO:0031146; GO:0043153; GO:0051726 45442 XM_044310789.1 48 33 101 8 54 NA NA NA NA NA NA 45443 XM_044326880.1 0 0 0 0 77 A1KZ92 6.4e-25 Probable oxidoreductase PXDNL (EC 1.-.-.-) (Cardiac peroxidase) (Inactive peroxidasin-like protein) (Polysomal ribonuclease 1) (PRM1) (Vascular peroxidase 2) Homo sapiens (Human) hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979] GO:0004519; GO:0004601; GO:0005615; GO:0005783; GO:0005886; GO:0006979; GO:0020037; GO:0042744; GO:0046872; GO:0140825 45444 XM_029338398.2 0 0 0 0 145 NA NA NA NA NA NA 45445 XM_029331377.2 250 152 145 179 223 Q18297 8.76e-145 Transient receptor potential cation channel subfamily A member 1 homolog Caenorhabditis elegans response to stimulus [GO:0050896] GO:0005216; GO:0005886; GO:0043025; GO:0050896; GO:0097730 45446 XM_029331377.2 250 152 145 179 223 Q18297 9.04e-28 Transient receptor potential cation channel subfamily A member 1 homolog Caenorhabditis elegans response to stimulus [GO:0050896] GO:0005216; GO:0005886; GO:0043025; GO:0050896; GO:0097730 45447 XM_044313051.1 137 41 108 94 74 Q5U2V4 9.33e-100 Phospholipase B-like 1 (EC 3.1.1.-) (LAMA-like protein 1) (Lamina ancestor homolog 1) (Phospholipase B domain-containing protein 1) [Cleaved into: Phospholipase B-like 1 chain A; Phospholipase B-like 1 chain B; Phospholipase B-like 1 chain C] Rattus norvegicus (Rat) phospholipid catabolic process [GO:0009395] GO:0004620; GO:0005576; GO:0005615; GO:0005764; GO:0009395 45448 XM_044316380.1 1137 950 717 881 687 NA NA NA NA NA NA 45449 XM_044316582.1 280 74 69 131 207 NA NA NA NA NA NA 45450 XM_029331422.2 342 245 241 224 289 Q7T3I0 5.3e-55 Zinc finger C4H2 domain-containing protein (Hepatocellular carcinoma-associated antigen 127 homolog) (Hepatocellular carcinoma-associated antigen 127-like) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399]; neuromuscular junction development [GO:0007528]; neuron development [GO:0048666]; neuron fate specification [GO:0048665]; positive regulation of neuron differentiation [GO:0045666]; spinal cord motor neuron differentiation [GO:0021522] GO:0005634; GO:0005737; GO:0007399; GO:0007528; GO:0021522; GO:0045211; GO:0045666; GO:0046872; GO:0048665; GO:0048666 45451 XM_044323057.1 53 84 60 0 83 Q24K03 3.91e-56 THUMP domain-containing protein 1 Bos taurus (Bovine) tRNA modification [GO:0006400] GO:0003723; GO:0006400 45452 XM_044324261.1 0 52 52 0 40 P07949 3.2e-50 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; axon guidance [GO:0007411]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; lymphocyte migration into lymphoid organs [GO:0097021]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; posterior midgut development [GO:0007497]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006468; GO:0006919; GO:0007156; GO:0007158; GO:0007165; GO:0007169; GO:0007411; GO:0007497; GO:0009410; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0038023; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0097021; GO:0098797; GO:2001241 45453 XM_044327136.1 27 14 47 42 57 NA NA NA NA NA NA 45454 XM_029347907.2 12 5 0 0 9 NA NA NA NA NA NA 45455 XM_029339536.2 42 7 26 30 58 NA NA NA NA NA NA 45456 XM_029355697.2 651 785 504 620 606 Q9Y6G5 5.76e-62 COMM domain-containing protein 10 Homo sapiens (Human) NA GO:0005654; GO:0005737 45457 XM_044318831.1 72 13 44 0 70 Q99315 1.3e-84 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 45458 XM_044313242.1 1011 628 672 2295 1177 P18460 1.95e-77 Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (Tyrosine kinase receptor CEK2) Gallus gallus (Chicken) apoptotic process [GO:0006915]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0004714; GO:0005007; GO:0005524; GO:0005886; GO:0006915; GO:0007169; GO:0008284; GO:0017134; GO:0033674; GO:0043235; GO:0043410 45459 XM_044307523.1 1666 697 696 1071 1043 Q8NDG6 0 ATP-dependent RNA helicase TDRD9 (EC 3.6.4.13) (Tudor domain-containing protein 9) Homo sapiens (Human) cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; fertilization [GO:0009566]; male meiosis I [GO:0007141]; male meiotic nuclear division [GO:0007140]; negative regulation of transposition [GO:0010529]; piRNA processing [GO:0034587]; spermatogenesis [GO:0007283] GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005737; GO:0007140; GO:0007141; GO:0007283; GO:0009566; GO:0010529; GO:0016887; GO:0030154; GO:0034587; GO:0043046; GO:0071547 45460 XM_029324156.2 337 316 133 232 194 NA NA NA NA NA NA 45461 XM_029352196.2 41 12 18 15 56 NA NA NA NA NA NA 45462 XM_029348529.2 2 0 1 7 14 Q63245 9.22e-28 Forkhead box protein D3 (HNF3/FH transcription factor genesis) (Hepatocyte nuclear factor 3 forkhead homolog 2) (HFH-2) Rattus norvegicus (Rat) anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; cellular response to leukemia inhibitory factor [GO:1990830]; embryonic placenta development [GO:0001892]; in utero embryonic development [GO:0001701]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; trophectodermal cell differentiation [GO:0001829] GO:0000122; GO:0000785; GO:0000976; GO:0000977; GO:0000978; GO:0000981; GO:0001227; GO:0001701; GO:0001829; GO:0001892; GO:0003677; GO:0003690; GO:0003700; GO:0005634; GO:0006355; GO:0006357; GO:0009653; GO:0030154; GO:0045944; GO:1990830; GO:1990837 45463 XR_006396395.1 38 59 48 23 68 NA NA NA NA NA NA 45464 XR_003824028.2 16 12 28 15 9 NA NA NA NA NA NA 45465 XR_006394601.1 7 7 16 10 3 NA NA NA NA NA NA 45466 XM_029354752.2 960 984 0 116 0 Q9EQC4 9.58e-64 Elongation of very long chain fatty acids protein 4 (EC 2.3.1.199) (3-keto acyl-CoA synthase Elovl4) (ELOVL fatty acid elongase 4) (ELOVL FA elongase 4) (Very long chain 3-ketoacyl-CoA synthase 4) (Very long chain 3-oxoacyl-CoA synthase 4) Mus musculus (Mouse) fatty acid elongation, monounsaturated fatty acid [GO:0034625]; fatty acid elongation, polyunsaturated fatty acid [GO:0034626]; fatty acid elongation, saturated fatty acid [GO:0019367]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; sphingolipid biosynthetic process [GO:0030148]; unsaturated fatty acid biosynthetic process [GO:0006636]; very long-chain fatty acid biosynthetic process [GO:0042761] GO:0005783; GO:0005789; GO:0006636; GO:0009922; GO:0019367; GO:0030148; GO:0034625; GO:0034626; GO:0035338; GO:0042761; GO:0102756 45467 XM_029351986.2 78 198 116 97 84 Q6DDH6 1.23e-40 Histone deacetylase complex subunit SAP130-A (130 kDa Sin3-associated polypeptide A) (Sin3-associated polypeptide p130 A) Xenopus laevis (African clawed frog) regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006355 45468 XM_029323452.2 5239 5018 2690 5151 4552 NA NA NA NA NA NA 45469 XM_029339441.2 34 0 45 28 76 NA NA NA NA NA NA 45470 XM_029341839.2 435 242 177 290 327 Q8BHT7 1.01e-97 RAB6A-GEF complex partner protein 2 (Retrograde Golgi transport protein RGP1 homolog) Mus musculus (Mouse) negative regulation of protein catabolic process [GO:0042177]; positive regulation of GTPase activity [GO:0043547]; retrograde transport, endosome to Golgi [GO:0042147] GO:0000139; GO:0005085; GO:0005829; GO:0005886; GO:0016020; GO:0031267; GO:0032991; GO:0034066; GO:0042147; GO:0042177; GO:0043547 45471 XM_029341830.2 4 4 1 6 28 NA NA NA NA NA NA 45472 XM_029330272.2 41 0 0 27 97 H1AFJ5 2.54e-41 Amiloride-sensitive sodium channel subunit alpha (Alpha-NaCH) (Epithelial Na(+) channel subunit alpha) (Alpha-ENaC) (Nonvoltage-gated sodium channel 1 subunit alpha) (SCNEA) Neoceratodus forsteri (Australian lungfish) (Ceratodus forsteri) sodium ion transmembrane transport [GO:0035725] GO:0001669; GO:0005737; GO:0015280; GO:0016324; GO:0031514; GO:0034706; GO:0035725 45473 XR_006391966.1 1 0 3 3 23 NA NA NA NA NA NA 45474 XM_029341724.2 15 56 74 78 78 Q921Y2 8.73e-69 U3 small nucleolar ribonucleoprotein protein IMP3 (U3 snoRNP protein IMP3) Mus musculus (Mouse) ribosomal small subunit biogenesis [GO:0042274]; rRNA processing [GO:0006364] GO:0003735; GO:0005634; GO:0005654; GO:0005730; GO:0006364; GO:0015935; GO:0019843; GO:0030515; GO:0030684; GO:0032040; GO:0034457; GO:0042274 45475 XM_029345187.2 17 25 5 33 28 NA NA NA NA NA NA 45476 XM_044314607.1 42 10 32 67 73 A4IGL7 3.74e-36 Peroxidasin (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0005576; GO:0005604; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0031012; GO:0042744; GO:0046872; GO:0051260; GO:0070207; GO:0070831; GO:0071711; GO:0140825 45477 XM_044314607.1 42 10 32 67 73 A4IGL7 6.84e-31 Peroxidasin (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0005576; GO:0005604; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0031012; GO:0042744; GO:0046872; GO:0051260; GO:0070207; GO:0070831; GO:0071711; GO:0140825 45478 XM_044311886.1 1358 844 962 1256 1696 NA NA NA NA NA NA 45479 XM_044323956.1 425 443 276 6 16 Q5RDY7 1.36e-173 Guanine nucleotide-binding protein subunit beta-5 (Gbeta5) (Transducin beta chain 5) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) dopamine receptor signaling pathway [GO:0007212]; negative regulation of voltage-gated calcium channel activity [GO:1901386] GO:0007212; GO:0016020; GO:0031682; GO:0051087; GO:1901386 45480 XM_029324423.2 3 0 6 7 1 NA NA NA NA NA NA 45481 XM_029333642.2 59 0 50 6 87 Q8WV37 2.27e-48 Zinc finger protein 480 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0046872 45482 XM_029333642.2 59 0 50 6 87 Q8WV37 3.55e-41 Zinc finger protein 480 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0046872 45483 XM_029333642.2 59 0 50 6 87 Q8WV37 1.93e-40 Zinc finger protein 480 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0046872 45484 XM_029333642.2 59 0 50 6 87 Q8WV37 3.38e-40 Zinc finger protein 480 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0046872 45485 XM_029333642.2 59 0 50 6 87 Q8WV37 6.35e-39 Zinc finger protein 480 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0046872 45486 XM_029333642.2 59 0 50 6 87 Q8WV37 3.75e-34 Zinc finger protein 480 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0046872 45487 XM_029333642.2 59 0 50 6 87 Q8WV37 4.5e-33 Zinc finger protein 480 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0046872 45488 XM_029333642.2 59 0 50 6 87 Q8WV37 1.81e-26 Zinc finger protein 480 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0046872 45489 XM_044316480.1 4 0 5 0 13 A2CG49 2.2e-23 Kalirin (EC 2.7.11.1) (Protein Duo) (Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain) Mus musculus (Mouse) adult locomotory behavior [GO:0008344]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; habituation [GO:0046959]; intracellular signal transduction [GO:0035556]; lactation [GO:0007595]; maternal behavior [GO:0042711]; maternal process involved in parturition [GO:0060137]; memory [GO:0007613]; modification of postsynaptic actin cytoskeleton [GO:0098885]; negative regulation of growth hormone secretion [GO:0060125]; nervous system development [GO:0007399]; neuromuscular junction development [GO:0007528]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; NMDA selective glutamate receptor signaling pathway [GO:0098989]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of GTPase activity [GO:0043547]; protein phosphorylation [GO:0006468]; regulation of dendrite development [GO:0050773]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; social behavior [GO:0035176] GO:0004674; GO:0005085; GO:0005524; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0006468; GO:0007399; GO:0007409; GO:0007411; GO:0007528; GO:0007595; GO:0007613; GO:0008344; GO:0014069; GO:0019898; GO:0019899; GO:0035176; GO:0035556; GO:0042711; GO:0043005; GO:0043025; GO:0043547; GO:0046872; GO:0046959; GO:0048471; GO:0050773; GO:0060125; GO:0060137; GO:0061003; GO:0098696; GO:0098793; GO:0098885; GO:0098978; GO:0098989; GO:0099645; GO:0106310; GO:1905274 45490 XM_029334030.2 1184 1476 1000 736 879 Q9EQT3 3.84e-67 Rho-related GTP-binding protein RhoU (Rho GTPase-like protein ARHU) (Wnt-1 responsive Cdc42 homolog 1) (WRCH-1) Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; Cdc42 protein signal transduction [GO:0032488]; cytoskeleton organization [GO:0007010]; endocytosis [GO:0006897]; establishment or maintenance of cell polarity [GO:0007163]; G1/S transition of mitotic cell cycle [GO:0000082]; Rac protein signal transduction [GO:0016601]; regulation of cell shape [GO:0008360] GO:0000082; GO:0000139; GO:0002102; GO:0003924; GO:0005525; GO:0005886; GO:0005925; GO:0006897; GO:0007010; GO:0007163; GO:0008360; GO:0016601; GO:0030036; GO:0032488; GO:0042995; GO:0046872 45491 XM_029343250.2 19 0 0 0 0 Q5F433 2.27e-26 PRA1 family protein 3 (ADP-ribosylation factor-like protein 6-interacting protein 5) (ARL-6-interacting protein 5) (Aip-5) Gallus gallus (Chicken) cellular response to organic cyclic compound [GO:0071407]; glutathione metabolic process [GO:0006749]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; L-glutamate import across plasma membrane [GO:0098712]; L-glutamate transmembrane transport [GO:0015813]; learning or memory [GO:0007611]; negative regulation of L-glutamate import across plasma membrane [GO:0002037]; negative regulation of mitochondrial membrane potential [GO:0010917]; negative regulation of transport [GO:0051051]; neuron death in response to oxidative stress [GO:0036475]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of stress-activated MAPK cascade [GO:0032874]; protein localization to plasma membrane [GO:0072659]; protein transport [GO:0015031] GO:0002037; GO:0005789; GO:0005856; GO:0005886; GO:0006749; GO:0007611; GO:0008631; GO:0010917; GO:0015031; GO:0015813; GO:0016020; GO:0032874; GO:0036475; GO:0043065; GO:0043280; GO:0051051; GO:0071407; GO:0072659; GO:0098712; GO:0099523 45492 XM_029325922.2 22177 28715 20289 19095 16826 P62912 2.36e-59 60S ribosomal protein L32 Rattus norvegicus (Rat) cellular response to dexamethasone stimulus [GO:0071549]; cytoplasmic translation [GO:0002181]; liver regeneration [GO:0097421] GO:0002181; GO:0003735; GO:0022625; GO:0022626; GO:0042788; GO:0045202; GO:0071549; GO:0097421 45493 XM_044317184.1 238 441 109 295 239 Q9NXX6 1.15e-41 Non-structural maintenance of chromosomes element 4 homolog A (NS4EA) (Non-SMC element 4 homolog A) Homo sapiens (Human) DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; positive regulation of response to DNA damage stimulus [GO:2001022]; protein sumoylation [GO:0016925]; regulation of telomere maintenance [GO:0032204] GO:0000724; GO:0000781; GO:0005634; GO:0005654; GO:0006281; GO:0016604; GO:0016925; GO:0030915; GO:0032204; GO:2001022 45494 XR_006392873.1 41 2 25 5 151 NA NA NA NA NA NA 45495 XM_029347968.2 25 0 0 9 4 NA NA NA NA NA NA 45496 XM_044326907.1 0 0 0 0 18 NA NA NA NA NA NA 45497 XM_029336051.2 25 263 88 75 55 NA NA NA NA NA NA 45498 XM_029340913.2 851 474 471 744 816 Q6NZC7 0 SEC23-interacting protein Mus musculus (Mouse) acrosome assembly [GO:0001675]; single fertilization [GO:0007338]; spermatid development [GO:0007286] GO:0001675; GO:0004620; GO:0005737; GO:0005794; GO:0005801; GO:0007286; GO:0007338; GO:0012507; GO:0030134; GO:0043231; GO:0046872; GO:0048471; GO:0070971; GO:0097038 45499 XM_044326509.1 778 744 545 1446 1139 Q96JI7 3.25e-128 Spatacsin (Colorectal carcinoma-associated protein) (Spastic paraplegia 11 protein) Homo sapiens (Human) autophagosome organization [GO:1905037]; axo-dendritic transport [GO:0008088]; axon extension [GO:0048675]; chemical synaptic transmission [GO:0007268]; cholesterol efflux [GO:0033344]; corticospinal tract morphogenesis [GO:0021957]; localization within membrane [GO:0051668]; lysosome organization [GO:0007040]; memory [GO:0007613]; motor behavior [GO:0061744]; motor neuron apoptotic process [GO:0097049]; neuromuscular junction development [GO:0007528]; phagosome-lysosome fusion involved in apoptotic cell clearance [GO:0090389]; protein import into nucleus [GO:0006606]; regulation of store-operated calcium entry [GO:2001256]; skeletal muscle fiber development [GO:0048741]; synaptic vesicle transport [GO:0048489]; walking behavior [GO:0090659] GO:0005730; GO:0005737; GO:0005765; GO:0005829; GO:0005886; GO:0006606; GO:0007040; GO:0007268; GO:0007528; GO:0007613; GO:0008088; GO:0019901; GO:0021957; GO:0030424; GO:0030425; GO:0031410; GO:0033344; GO:0045202; GO:0048489; GO:0048675; GO:0048741; GO:0051668; GO:0061744; GO:0090389; GO:0090659; GO:0097049; GO:1905037; GO:2001256 45500 XM_044326509.1 778 744 545 1446 1139 Q96JI7 3.67e-101 Spatacsin (Colorectal carcinoma-associated protein) (Spastic paraplegia 11 protein) Homo sapiens (Human) autophagosome organization [GO:1905037]; axo-dendritic transport [GO:0008088]; axon extension [GO:0048675]; chemical synaptic transmission [GO:0007268]; cholesterol efflux [GO:0033344]; corticospinal tract morphogenesis [GO:0021957]; localization within membrane [GO:0051668]; lysosome organization [GO:0007040]; memory [GO:0007613]; motor behavior [GO:0061744]; motor neuron apoptotic process [GO:0097049]; neuromuscular junction development [GO:0007528]; phagosome-lysosome fusion involved in apoptotic cell clearance [GO:0090389]; protein import into nucleus [GO:0006606]; regulation of store-operated calcium entry [GO:2001256]; skeletal muscle fiber development [GO:0048741]; synaptic vesicle transport [GO:0048489]; walking behavior [GO:0090659] GO:0005730; GO:0005737; GO:0005765; GO:0005829; GO:0005886; GO:0006606; GO:0007040; GO:0007268; GO:0007528; GO:0007613; GO:0008088; GO:0019901; GO:0021957; GO:0030424; GO:0030425; GO:0031410; GO:0033344; GO:0045202; GO:0048489; GO:0048675; GO:0048741; GO:0051668; GO:0061744; GO:0090389; GO:0090659; GO:0097049; GO:1905037; GO:2001256 45501 XM_029343780.2 539 228 113 533 283 NA NA NA NA NA NA 45502 XM_044312760.1 304 191 219 277 599 NA NA NA NA NA NA 45503 XM_029345387.2 677 657 614 960 814 O75319 3.02e-43 RNA/RNP complex-1-interacting phosphatase (EC 3.1.3.-) (Dual specificity protein phosphatase 11) (Phosphatase that interacts with RNA/RNP complex 1) Homo sapiens (Human) protein dephosphorylation [GO:0006470]; RNA processing [GO:0006396] GO:0001650; GO:0003723; GO:0004651; GO:0004725; GO:0005634; GO:0005654; GO:0006396; GO:0006470; GO:0008138; GO:0016607; GO:0016791; GO:0045171 45504 XM_029342492.2 847 691 571 856 1148 Q5RBL6 1.47e-81 Golgi SNAP receptor complex member 1 (28 kDa Golgi SNARE protein) (28 kDa cis-Golgi SNARE p28) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; protein transport [GO:0015031] GO:0000139; GO:0005801; GO:0006888; GO:0015031 45505 XM_029328301.2 270 220 82 296 189 NA NA NA NA NA NA 45506 XM_044313578.1 52 33 25 31 114 Q5F371 1.16e-60 Protein strawberry notch homolog 1 Gallus gallus (Chicken) regulation of DNA-templated transcription [GO:0006355]; regulation of response to stimulus [GO:0048583] GO:0005634; GO:0006355; GO:0031490; GO:0042393; GO:0048583 45507 XR_006392684.1 0 46 10 33 55 NA NA NA NA NA NA 45508 XM_044329154.1 43 28 16 146 40 NA NA NA NA NA NA 45509 XM_029357277.2 4283 2229 1931 3148 2624 Q16720 0 Plasma membrane calcium-transporting ATPase 3 (PMCA3) (EC 7.2.2.10) (Plasma membrane calcium ATPase isoform 3) (Plasma membrane calcium pump isoform 3) Homo sapiens (Human) calcium ion export across plasma membrane [GO:1990034]; cellular calcium ion homeostasis [GO:0006874]; ion transmembrane transport [GO:0034220]; regulation of cardiac conduction [GO:1903779]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0005388; GO:0005516; GO:0005524; GO:0005886; GO:0006874; GO:0015085; GO:0016887; GO:0019829; GO:0030165; GO:0034220; GO:0042734; GO:0043231; GO:0046872; GO:0051480; GO:0098688; GO:0098978; GO:0098982; GO:1903561; GO:1903779; GO:1905056; GO:1990032; GO:1990034 45510 XM_029350918.2 9541 11405 9346 23986 23083 Q9C8G5 5.28e-90 CSC1-like protein ERD4 (Hyperosmolality-gated Ca2+ permeable channel 3.1) (AtOSCA3.1) (Protein EARLY-RESPONSIVE TO DEHYDRATION STRESS 4) Arabidopsis thaliana (Mouse-ear cress) NA GO:0000325; GO:0003729; GO:0005227; GO:0005634; GO:0005886; GO:0009506; GO:0009941 45511 XM_029351354.2 416 341 246 344 455 D3ZAT9 8.88e-43 Failed axon connections homolog Rattus norvegicus (Rat) NA GO:0005737; GO:0016020 45512 XM_029335733.2 15 0 5 0 15 NA NA NA NA NA NA 45513 XM_044315780.1 4 21 22 0 0 NA NA NA NA NA NA 45514 XM_029336311.2 1417 1035 885 1161 1321 Q5FVF4 5.07e-67 Transmembrane 7 superfamily member 3 Rattus norvegicus (Rat) cellular response to unfolded protein [GO:0034620]; negative regulation of programmed cell death [GO:0043069]; positive regulation of insulin secretion [GO:0032024] GO:0005886; GO:0032024; GO:0034620; GO:0043069 45515 XM_029327057.2 1188 1416 670 1079 598 P49419 0 Alpha-aminoadipic semialdehyde dehydrogenase (Alpha-AASA dehydrogenase) (EC 1.2.1.31) (Aldehyde dehydrogenase family 7 member A1) (EC 1.2.1.3) (Antiquitin-1) (Betaine aldehyde dehydrogenase) (EC 1.2.1.8) (Delta1-piperideine-6-carboxylate dehydrogenase) (P6c dehydrogenase) Homo sapiens (Human) cellular aldehyde metabolic process [GO:0006081]; choline catabolic process [GO:0042426]; glycine betaine biosynthetic process from choline [GO:0019285]; sensory perception of sound [GO:0007605] GO:0004029; GO:0004043; GO:0005634; GO:0005739; GO:0005759; GO:0005829; GO:0006081; GO:0007605; GO:0008802; GO:0019285; GO:0042426; GO:0042802; GO:0043878; GO:0070062 45516 XM_044322525.1 393 610 558 317 678 Q8VE65 8.8e-55 Transcription initiation factor TFIID subunit 12 (Transcription initiation factor TFIID 20 kDa subunits) (TAFII-20) (TAFII20) Mus musculus (Mouse) DNA-templated transcription initiation [GO:0006352]; histone acetylation [GO:0016573]; histone H3 acetylation [GO:0043966]; monoubiquitinated histone deubiquitination [GO:0035521]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; mRNA transcription by RNA polymerase II [GO:0042789]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of DNA-templated transcription [GO:0006355]; regulation of RNA splicing [GO:0043484]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription initiation at RNA polymerase II promoter [GO:0006367] GO:0000124; GO:0003677; GO:0003713; GO:0005634; GO:0005669; GO:0006282; GO:0006352; GO:0006355; GO:0006357; GO:0006367; GO:0006468; GO:0016251; GO:0016573; GO:0017025; GO:0033276; GO:0035521; GO:0035522; GO:0042789; GO:0043484; GO:0043966; GO:0045893; GO:0045944; GO:0046695; GO:0046982; GO:0051091; GO:0051123; GO:0060261; GO:0140297 45517 XM_044307097.1 63 3 38 31 0 NA NA NA NA NA NA 45518 XM_044324031.1 46 16 99 23 106 Q0V9W6 2.49e-36 BTB/POZ domain-containing protein 6 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737 45519 XM_029347387.2 3330 2730 2217 2350 2112 NA NA NA NA NA NA 45520 XR_006397888.1 19 62 120 68 0 NA NA NA NA NA NA 45521 XR_006393178.1 165 17 58 0 19 NA NA NA NA NA NA 45522 XM_044318786.1 17790 18412 10817 18399 17075 Q3B7N2 0 Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (F-actin cross-linking protein) (Non-muscle alpha-actinin-1) Bos taurus (Bovine) establishment of localization [GO:0051234]; regulation of ATP-dependent activity [GO:0043462]; regulation of neurotransmitter secretion [GO:0046928]; sarcomere organization [GO:0045214]; skeletal muscle fiber development [GO:0048741] GO:0001725; GO:0001726; GO:0005509; GO:0005523; GO:0005915; GO:0005923; GO:0005925; GO:0012506; GO:0016328; GO:0017166; GO:0030018; GO:0030027; GO:0030486; GO:0031252; GO:0042383; GO:0042803; GO:0043462; GO:0043495; GO:0045214; GO:0046928; GO:0048741; GO:0051015; GO:0051234; GO:0051393; GO:0090636; GO:0090637; GO:0097433; GO:1990357 45523 XM_029337350.2 1115 652 674 755 806 NA NA NA NA NA NA 45524 XM_029356761.2 1248 688 537 339 388 NA NA NA NA NA NA 45525 XM_029330653.2 3472 2495 1529 2771 2918 Q5RDE7 0 Cysteine desulfurase (EC 2.8.1.7) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) [2Fe-2S] cluster assembly [GO:0044571]; [4Fe-4S] cluster assembly [GO:0044572]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777] GO:0005634; GO:0005739; GO:0006777; GO:0030170; GO:0031071; GO:0042803; GO:0044571; GO:0044572; GO:0046872; GO:0051536; GO:0099128 45526 XM_044324738.1 819 878 485 1083 597 Q32TF8 0 EF-hand domain-containing family member C2 Danio rerio (Zebrafish) (Brachydanio rerio) cilium-dependent cell motility [GO:0060285]; mitotic cytokinesis [GO:0000281]; mitotic spindle organization [GO:0007052]; multi-ciliated epithelial cell differentiation [GO:1903251]; regulation of neuron projection development [GO:0010975]; specification of pronephric distal tubule identity [GO:0039010] GO:0000281; GO:0005879; GO:0005930; GO:0007052; GO:0010975; GO:0039010; GO:0043014; GO:0060285; GO:0072686; GO:1903251 45527 XM_044319101.1 16 15 0 3 1 O62852 2.36e-91 Short transient receptor potential channel 5 (Rtrp5) (TrpC5) (Capacitative calcium entry channel 2) (CCE2) Oryctolagus cuniculus (Rabbit) neuron apoptotic process [GO:0051402]; phosphatidylserine exposure on apoptotic cell surface [GO:0070782] GO:0005262; GO:0005886; GO:0034704; GO:0051402; GO:0070679; GO:0070782 45528 XM_044309867.1 6 0 1 4 0 NA NA NA NA NA NA 45529 XM_044309367.1 0 0 0 0 15 O60290 1.39e-26 Zinc finger protein 862 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006355; GO:0046872; GO:0046983 45530 XM_044309367.1 0 0 0 0 15 O60290 1.39e-26 Zinc finger protein 862 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006355; GO:0046872; GO:0046983 45531 XM_029329670.2 66 139 39 79 51 Q26619 1.47e-118 cAMP-dependent protein kinase type II regulatory subunit Strongylocentrotus purpuratus (Purple sea urchin) negative regulation of cAMP-dependent protein kinase activity [GO:2000480] GO:0004862; GO:0005737; GO:0005952; GO:0030552; GO:0034236; GO:2000480 45532 XM_044313335.1 1574 512 787 1683 1833 P42859 0 Huntingtin (Huntington disease protein homolog) (HD protein homolog) [Cleaved into: Huntingtin, myristoylated N-terminal fragment] Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; anterior/posterior pattern specification [GO:0009952]; associative learning [GO:0008306]; axo-dendritic transport [GO:0008088]; brain development [GO:0007420]; cellular senescence [GO:0090398]; central nervous system development [GO:0007417]; citrulline metabolic process [GO:0000052]; determination of adult lifespan [GO:0008340]; dopamine receptor signaling pathway [GO:0007212]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endosomal transport [GO:0016197]; establishment of mitotic spindle orientation [GO:0000132]; gastrulation [GO:0007369]; Golgi organization [GO:0007030]; grooming behavior [GO:0007625]; hormone metabolic process [GO:0042445]; insulin secretion [GO:0030073]; iron ion homeostasis [GO:0055072]; lactate biosynthetic process from pyruvate [GO:0019244]; learning [GO:0007612]; learning or memory [GO:0007611]; locomotory behavior [GO:0007626]; microtubule-based transport [GO:0099111]; mitochondrial transport [GO:0006839]; mitochondrion organization [GO:0007005]; mRNA transport [GO:0051028]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; neural plate formation [GO:0021990]; neurogenesis [GO:0022008]; neuron development [GO:0048666]; olfactory lobe development [GO:0021988]; paraxial mesoderm formation [GO:0048341]; peptide hormone secretion [GO:0030072]; positive regulation of aggrephagy [GO:1905337]; positive regulation of apoptotic process [GO:0043065]; positive regulation of autophagy of mitochondrion [GO:1903599]; positive regulation of cilium assembly [GO:0045724]; positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031587]; positive regulation of lipophagy [GO:1904504]; positive regulation of motile cilium assembly [GO:1905505]; positive regulation of non-motile cilium assembly [GO:1902857]; postsynapse to nucleus signaling pathway [GO:0099527]; protein destabilization [GO:0031648]; protein localization to centrosome [GO:0071539]; protein localization to nucleus [GO:0034504]; quinolinate biosynthetic process [GO:0019805]; regulation of CAMKK-AMPK signaling cascade [GO:1905289]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of gene expression [GO:0010468]; regulation of intracellular mRNA localization [GO:1904580]; regulation of neuron apoptotic process [GO:0043523]; regulation of phosphoprotein phosphatase activity [GO:0043666]; regulation of protein localization to nucleus [GO:1900180]; regulation of synaptic plasticity [GO:0048167]; response to calcium ion [GO:0051592]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; social behavior [GO:0035176]; spermatogenesis [GO:0007283]; striatum development [GO:0021756]; urea cycle [GO:0000050]; vesicle transport along microtubule [GO:0047496]; visual learning [GO:0008542]; vocal learning [GO:0042297] GO:0000050; GO:0000052; GO:0000132; GO:0002039; GO:0005102; GO:0005522; GO:0005634; GO:0005654; GO:0005737; GO:0005769; GO:0005770; GO:0005776; GO:0005783; GO:0005794; GO:0005814; GO:0005829; GO:0006839; GO:0006888; GO:0006890; GO:0007005; GO:0007029; GO:0007030; GO:0007212; GO:0007283; GO:0007369; GO:0007417; GO:0007420; GO:0007611; GO:0007612; GO:0007625; GO:0007626; GO:0008088; GO:0008306; GO:0008340; GO:0008542; GO:0009653; GO:0009952; GO:0010468; GO:0014069; GO:0016197; GO:0016234; GO:0019244; GO:0019805; GO:0019900; GO:0021756; GO:0021988; GO:0021990; GO:0022008; GO:0030072; GO:0030073; GO:0030136; GO:0030424; GO:0030425; GO:0030659; GO:0031072; GO:0031410; GO:0031587; GO:0031648; GO:0032991; GO:0034452; GO:0034504; GO:0035176; GO:0042297; GO:0042445; GO:0042802; GO:0043025; GO:0043065; GO:0043066; GO:0043523; GO:0043666; GO:0044325; GO:0045505; GO:0045724; GO:0047496; GO:0048167; GO:0048341; GO:0048471; GO:0048487; GO:0048666; GO:0050809; GO:0051028; GO:0051592; GO:0055072; GO:0071539; GO:0071598; GO:0090398; GO:0097060; GO:0098978; GO:0099111; GO:0099523; GO:0099524; GO:0099527; GO:1900180; GO:1902857; GO:1903599; GO:1904504; GO:1904580; GO:1905289; GO:1905337; GO:1905505; GO:2000117; GO:2000479; GO:2001237 45533 XM_044313335.1 1574 512 787 1683 1833 P42859 2.94e-56 Huntingtin (Huntington disease protein homolog) (HD protein homolog) [Cleaved into: Huntingtin, myristoylated N-terminal fragment] Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; anterior/posterior pattern specification [GO:0009952]; associative learning [GO:0008306]; axo-dendritic transport [GO:0008088]; brain development [GO:0007420]; cellular senescence [GO:0090398]; central nervous system development [GO:0007417]; citrulline metabolic process [GO:0000052]; determination of adult lifespan [GO:0008340]; dopamine receptor signaling pathway [GO:0007212]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endosomal transport [GO:0016197]; establishment of mitotic spindle orientation [GO:0000132]; gastrulation [GO:0007369]; Golgi organization [GO:0007030]; grooming behavior [GO:0007625]; hormone metabolic process [GO:0042445]; insulin secretion [GO:0030073]; iron ion homeostasis [GO:0055072]; lactate biosynthetic process from pyruvate [GO:0019244]; learning [GO:0007612]; learning or memory [GO:0007611]; locomotory behavior [GO:0007626]; microtubule-based transport [GO:0099111]; mitochondrial transport [GO:0006839]; mitochondrion organization [GO:0007005]; mRNA transport [GO:0051028]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; neural plate formation [GO:0021990]; neurogenesis [GO:0022008]; neuron development [GO:0048666]; olfactory lobe development [GO:0021988]; paraxial mesoderm formation [GO:0048341]; peptide hormone secretion [GO:0030072]; positive regulation of aggrephagy [GO:1905337]; positive regulation of apoptotic process [GO:0043065]; positive regulation of autophagy of mitochondrion [GO:1903599]; positive regulation of cilium assembly [GO:0045724]; positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031587]; positive regulation of lipophagy [GO:1904504]; positive regulation of motile cilium assembly [GO:1905505]; positive regulation of non-motile cilium assembly [GO:1902857]; postsynapse to nucleus signaling pathway [GO:0099527]; protein destabilization [GO:0031648]; protein localization to centrosome [GO:0071539]; protein localization to nucleus [GO:0034504]; quinolinate biosynthetic process [GO:0019805]; regulation of CAMKK-AMPK signaling cascade [GO:1905289]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of gene expression [GO:0010468]; regulation of intracellular mRNA localization [GO:1904580]; regulation of neuron apoptotic process [GO:0043523]; regulation of phosphoprotein phosphatase activity [GO:0043666]; regulation of protein localization to nucleus [GO:1900180]; regulation of synaptic plasticity [GO:0048167]; response to calcium ion [GO:0051592]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; social behavior [GO:0035176]; spermatogenesis [GO:0007283]; striatum development [GO:0021756]; urea cycle [GO:0000050]; vesicle transport along microtubule [GO:0047496]; visual learning [GO:0008542]; vocal learning [GO:0042297] GO:0000050; GO:0000052; GO:0000132; GO:0002039; GO:0005102; GO:0005522; GO:0005634; GO:0005654; GO:0005737; GO:0005769; GO:0005770; GO:0005776; GO:0005783; GO:0005794; GO:0005814; GO:0005829; GO:0006839; GO:0006888; GO:0006890; GO:0007005; GO:0007029; GO:0007030; GO:0007212; GO:0007283; GO:0007369; GO:0007417; GO:0007420; GO:0007611; GO:0007612; GO:0007625; GO:0007626; GO:0008088; GO:0008306; GO:0008340; GO:0008542; GO:0009653; GO:0009952; GO:0010468; GO:0014069; GO:0016197; GO:0016234; GO:0019244; GO:0019805; GO:0019900; GO:0021756; GO:0021988; GO:0021990; GO:0022008; GO:0030072; GO:0030073; GO:0030136; GO:0030424; GO:0030425; GO:0030659; GO:0031072; GO:0031410; GO:0031587; GO:0031648; GO:0032991; GO:0034452; GO:0034504; GO:0035176; GO:0042297; GO:0042445; GO:0042802; GO:0043025; GO:0043065; GO:0043066; GO:0043523; GO:0043666; GO:0044325; GO:0045505; GO:0045724; GO:0047496; GO:0048167; GO:0048341; GO:0048471; GO:0048487; GO:0048666; GO:0050809; GO:0051028; GO:0051592; GO:0055072; GO:0071539; GO:0071598; GO:0090398; GO:0097060; GO:0098978; GO:0099111; GO:0099523; GO:0099524; GO:0099527; GO:1900180; GO:1902857; GO:1903599; GO:1904504; GO:1904580; GO:1905289; GO:1905337; GO:1905505; GO:2000117; GO:2000479; GO:2001237 45534 XM_044320689.1 23 0 100 17 259 P22455 2.37e-38 Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen CD334) Homo sapiens (Human) cell migration [GO:0016477]; cholesterol homeostasis [GO:0042632]; fibroblast growth factor receptor signaling pathway [GO:0008543]; glucose homeostasis [GO:0042593]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphate ion homeostasis [GO:0055062]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of proteolysis [GO:0045862]; protein autophosphorylation [GO:0046777]; regulation of bile acid biosynthetic process [GO:0070857]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of lipid metabolic process [GO:0019216]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0004714; GO:0005007; GO:0005524; GO:0005576; GO:0005768; GO:0005783; GO:0005794; GO:0005886; GO:0007169; GO:0008201; GO:0008284; GO:0008543; GO:0010628; GO:0010715; GO:0016477; GO:0017134; GO:0018108; GO:0019216; GO:0030133; GO:0033674; GO:0042593; GO:0042632; GO:0043085; GO:0043235; GO:0045862; GO:0046777; GO:0055062; GO:0070374; GO:0070857; GO:2000573 45535 XM_029333743.2 0 0 35 81 201 Q61176 8.15e-90 Arginase-1 (EC 3.5.3.1) (Liver-type arginase) (Type I arginase) Mus musculus (Mouse) adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; negative regulation of type II interferon-mediated signaling pathway [GO:0060336]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; regulation of L-arginine import across plasma membrane [GO:1905541]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to xenobiotic stimulus [GO:0009410]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050] GO:0000050; GO:0001889; GO:0001938; GO:0002250; GO:0004053; GO:0005615; GO:0005737; GO:0005741; GO:0005829; GO:0006525; GO:0007568; GO:0009410; GO:0009635; GO:0010042; GO:0010043; GO:0010269; GO:0014075; GO:0019547; GO:0030145; GO:0030324; GO:0032964; GO:0033189; GO:0033197; GO:0042130; GO:0042802; GO:0042832; GO:0043005; GO:0043025; GO:0043200; GO:0045087; GO:0046007; GO:0046686; GO:0048678; GO:0051597; GO:0060056; GO:0060135; GO:0060336; GO:0070301; GO:0070965; GO:0071222; GO:0071353; GO:0071377; GO:0071549; GO:0071560; GO:1905541; GO:2000552 45536 XM_029355711.2 479 263 252 226 343 NA NA NA NA NA NA 45537 XM_029346893.2 90 43 23 105 60 Q9DBN1 3.43e-27 Stimulated by retinoic acid gene 6 protein-like (STRA6-like protein) (Retinol-binding protein 4 receptor 2) (RBP4 receptor 2) Mus musculus (Mouse) establishment of localization in cell [GO:0051649]; retinol transport [GO:0034633]; vitamin A import into cell [GO:0071939] GO:0005886; GO:0034633; GO:0051649; GO:0071939 45538 XM_029343182.2 34 224 15 346 0 NA NA NA NA NA NA 45539 XM_029348767.2 127 31 131 169 362 Q8NCC3 1.14e-103 Phospholipase A2 group XV (1-O-acylceramide synthase) (ACS) (LCAT-like lysophospholipase) (LLPL) (EC 3.1.1.5) (Lysophospholipase 3) (Lysosomal phospholipase A and acyltransferase) (EC 2.3.1.-, EC 3.1.1.32, EC 3.1.1.4) (Lysosomal phospholipase A2) (LPLA2) Homo sapiens (Human) ceramide metabolic process [GO:0006672]; diacylglycerol biosynthetic process [GO:0006651]; fatty acid catabolic process [GO:0009062]; glycerophospholipid metabolic process [GO:0006650]; lipid metabolic process [GO:0006629]; phosphatidylcholine catabolic process [GO:0034638]; phosphatidylcholine metabolic process [GO:0046470]; phosphatidylethanolamine catabolic process [GO:0046338]; phosphatidylglycerol metabolic process [GO:0046471]; phosphatidylserine metabolic process [GO:0006658]; phospholipid metabolic process [GO:0006644] GO:0004622; GO:0005543; GO:0005576; GO:0005615; GO:0005654; GO:0005764; GO:0006629; GO:0006644; GO:0006650; GO:0006651; GO:0006658; GO:0006672; GO:0008270; GO:0008374; GO:0008970; GO:0009062; GO:0016020; GO:0016411; GO:0034638; GO:0043231; GO:0046338; GO:0046470; GO:0046471; GO:0047499; GO:0052739; GO:0052740; GO:0070062; GO:0102545 45540 XM_044306945.1 0 8 0 13 13 NA NA NA NA NA NA 45541 XM_044315800.1 13 5 14 12 39 NA NA NA NA NA NA 45542 XM_029339464.2 588 588 220 535 320 NA NA NA NA NA NA 45543 XM_029335274.2 967 466 293 444 279 Q26636 3.26e-130 Cathepsin L (EC 3.4.22.15) [Cleaved into: Cathepsin L heavy chain; Cathepsin L light chain] Sarcophaga peregrina (Flesh fly) (Boettcherisca peregrina) cell differentiation [GO:0030154]; proteolysis [GO:0006508] GO:0004197; GO:0005764; GO:0006508; GO:0030154 45544 XM_029357637.2 776 142 63 452 167 NA NA NA NA NA NA 45545 XM_029342768.2 54 36 45 68 73 E7FAM5 1.65e-79 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 45546 XM_044327986.1 25 20 18 6 14 NA NA NA NA NA NA 45547 XM_029335093.2 9 1 1 18 5 NA NA NA NA NA NA 45548 XM_029353295.2 1 12 43 51 14 Q09575 1.59e-51 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 45549 XM_044329246.1 444 218 302 583 398 Q8R0C0 4.47e-21 DNA-directed RNA polymerase III subunit RPC7-like (RNA polymerase III subunit C7-like) (DNA-directed RNA polymerase III subunit G-like) Mus musculus (Mouse) transcription by RNA polymerase III [GO:0006383] GO:0003682; GO:0005634; GO:0005666; GO:0006383 45550 XM_029328607.2 434 280 229 342 392 O88554 0 Poly [ADP-ribose] polymerase 2 (PARP-2) (mPARP-2) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 2) (ARTD2) (DNA ADP-ribosyltransferase PARP2) (EC 2.4.2.-) (NAD(+) ADP-ribosyltransferase 2) (ADPRT-2) (Poly[ADP-ribose] synthase 2) (pADPRT-2) (Protein poly-ADP-ribosyltransferase PARP2) (EC 2.4.2.-) Mus musculus (Mouse) base-excision repair [GO:0006284]; decidualization [GO:0046697]; DNA ADP-ribosylation [GO:0030592]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; extrinsic apoptotic signaling pathway [GO:0097191]; histone modification [GO:0016570]; negative regulation of neuron death [GO:1901215]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; protein auto-ADP-ribosylation [GO:0070213]; protein poly-ADP-ribosylation [GO:0070212] GO:0003682; GO:0003684; GO:0003950; GO:0005634; GO:0005654; GO:0005730; GO:0006281; GO:0006284; GO:0006302; GO:0016570; GO:0016779; GO:0030592; GO:0031491; GO:0046697; GO:0061051; GO:0070212; GO:0070213; GO:0072572; GO:0090734; GO:0097191; GO:0140294; GO:0140805; GO:0140806; GO:0140807; GO:1901215; GO:1990404 45551 XM_044315851.1 0 9 0 9 0 NA NA NA NA NA NA 45552 XM_029340190.2 61 0 0 28 0 Q05096 0 Unconventional myosin-Ib (Myosin I alpha) (MMI-alpha) (MMIa) (Myosin heavy chain myr 1) Rattus norvegicus (Rat) actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; actin filament-based movement [GO:0030048]; nervous system development [GO:0007399]; post-Golgi vesicle-mediated transport [GO:0006892]; transferrin transport [GO:0033572]; vesicle transport along actin filament [GO:0030050] GO:0000146; GO:0003774; GO:0003779; GO:0005516; GO:0005524; GO:0005546; GO:0005547; GO:0005737; GO:0005769; GO:0005884; GO:0005886; GO:0005902; GO:0005903; GO:0006892; GO:0007015; GO:0007399; GO:0010008; GO:0015629; GO:0016459; GO:0030048; GO:0030050; GO:0030175; GO:0031982; GO:0032588; GO:0033572; GO:0045177; GO:0048471; GO:0051015; GO:0051017; GO:0071944 45553 XM_029334034.2 16 29 0 8 51 Q561X3 1.63e-37 Mediator of RNA polymerase II transcription subunit 4 (Mediator complex subunit 4) Danio rerio (Zebrafish) (Brachydanio rerio) regulation of transcription by RNA polymerase II [GO:0006357] GO:0003712; GO:0006357; GO:0016592; GO:0070847 45554 XM_044312886.1 25 12 4 10 1 NA NA NA NA NA NA 45555 XM_029340774.2 20608 16258 13308 27904 31353 Q63028 8.02e-100 Alpha-adducin (Erythrocyte adducin subunit alpha) Rattus norvegicus (Rat) actin filament bundle assembly [GO:0051017]; barbed-end actin filament capping [GO:0051016]; cell morphogenesis [GO:0000902]; cell volume homeostasis [GO:0006884]; cellular response to calcium ion [GO:0071277]; cellular response to retinoic acid [GO:0071300]; cytoskeleton organization [GO:0007010]; erythrocyte differentiation [GO:0030218]; hemoglobin metabolic process [GO:0020027]; homeostasis of number of cells within a tissue [GO:0048873]; in utero embryonic development [GO:0001701]; ion transport [GO:0006811]; multicellular organism growth [GO:0035264]; negative regulation of actin filament polymerization [GO:0030837]; positive regulation of adherens junction organization [GO:1903393]; positive regulation of angiogenesis [GO:0045766]; positive regulation of endocytosis [GO:0045807]; positive regulation of establishment of endothelial barrier [GO:1903142]; positive regulation of protein binding [GO:0032092] GO:0000902; GO:0001701; GO:0005200; GO:0005516; GO:0005634; GO:0005737; GO:0005856; GO:0005886; GO:0005912; GO:0006811; GO:0006884; GO:0007010; GO:0008290; GO:0014069; GO:0016020; GO:0020027; GO:0030218; GO:0030425; GO:0030507; GO:0030837; GO:0032092; GO:0035264; GO:0042608; GO:0042803; GO:0043197; GO:0045202; GO:0045766; GO:0045807; GO:0046982; GO:0048471; GO:0048873; GO:0051015; GO:0051016; GO:0051017; GO:0061629; GO:0071277; GO:0071300; GO:1903142; GO:1903393 45556 XM_029327297.2 35 4 11 43 176 NA NA NA NA NA NA 45557 XM_029328678.2 402 321 165 221 368 NA NA NA NA NA NA 45558 XM_029324292.2 138 25 30 13 173 NA NA NA NA NA NA 45559 XM_044315080.1 0 3 0 0 18 Q9VBW3 7.19e-48 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 45560 XM_044316810.1 295 105 116 218 231 NA NA NA NA NA NA 45561 XR_003824275.2 940 1170 615 618 632 NA NA NA NA NA NA 45562 XM_044324423.1 238 92 117 150 102 NA NA NA NA NA NA 45563 XM_029346137.2 877 659 409 816 838 O94776 3.99e-178 Metastasis-associated protein MTA2 (Metastasis-associated 1-like 1) (MTA1-L1 protein) (p53 target protein in deacetylase complex) Homo sapiens (Human) chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; DNA methylation [GO:0006306]; histone deacetylation [GO:0016575]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell fate specification [GO:0042659]; regulation of fibroblast migration [GO:0010762]; regulation of stem cell differentiation [GO:2000736] GO:0000118; GO:0000122; GO:0000781; GO:0000785; GO:0003682; GO:0003713; GO:0003714; GO:0004407; GO:0005634; GO:0005654; GO:0005667; GO:0006306; GO:0006325; GO:0006338; GO:0010762; GO:0016020; GO:0016575; GO:0016581; GO:0032991; GO:0042659; GO:0042826; GO:0043565; GO:0045892; GO:0045893; GO:0045944; GO:0046872; GO:0061629; GO:2000736 45564 XM_044327138.1 12 7 12 0 0 NA NA NA NA NA NA 45565 XM_029340261.2 8 28 0 0 0 NA NA NA NA NA NA 45566 XM_029357330.2 18606 19721 16027 10335 15135 Q9CQM5 1.62e-23 Thioredoxin domain-containing protein 17 (14 kDa thioredoxin-related protein) (TRP14) (Protein 42-9-9) (Thioredoxin-like protein 5) Mus musculus (Mouse) tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0004601; GO:0005829; GO:0033209; GO:0047134 45567 XM_044315028.1 34 104 99 60 31 NA NA NA NA NA NA 45568 XM_044307628.1 361 183 158 363 579 I3PB37 8.27e-110 4-coumarate:CoA ligase 1 (Ph-4CL1) (Ph4CL1) (EC 6.2.1.12) ((E)-caffeate:CoA ligase 4CL1) (EC 6.2.1.-) (Benzoate:CoA ligase 4CL1) (EC 6.2.1.25) (Trans-cinnamate:CoA ligase 4CL1) (EC 6.2.1.-) (Trans-ferulate:CoA ligase 4CL1) (EC 6.2.1.-) Petunia hybrida (Petunia) cinnamic acid biosynthetic process [GO:0009800]; cinnamic acid metabolic process [GO:0009803]; circadian rhythm [GO:0007623]; ferulate metabolic process [GO:0033494]; phenylpropanoid metabolic process [GO:0009698]; phytoalexin biosynthetic process [GO:0052315] GO:0005524; GO:0005829; GO:0007623; GO:0009698; GO:0009800; GO:0009803; GO:0016207; GO:0016405; GO:0018858; GO:0033494; GO:0050563; GO:0052315; GO:0106286; GO:0106290 45569 XM_029344646.2 0 23 0 0 0 Q9JHE4 1.79e-46 Galactosylceramide sulfotransferase (GalCer sulfotransferase) (EC 2.8.2.11) (3'-phosphoadenosine-5'-phosphosulfate:GalCer sulfotransferase) (3'-phosphoadenylylsulfate:galactosylceramide 3'-sulfotransferase) (Cerebroside sulfotransferase) Mus musculus (Mouse) galactosylceramide biosynthetic process [GO:0006682]; galactosylceramide metabolic process [GO:0006681]; glycerolipid metabolic process [GO:0046486]; glycolipid biosynthetic process [GO:0009247]; myelination [GO:0042552]; spermatogenesis [GO:0007283]; sphingolipid metabolic process [GO:0006665] GO:0000139; GO:0001733; GO:0006665; GO:0006681; GO:0006682; GO:0007283; GO:0008146; GO:0009247; GO:0016020; GO:0042552; GO:0046486; GO:0050694 45570 XM_029329777.2 204 296 15 15 11 Q6AYM1 7.11e-29 Uncharacterized protein C5orf34 homolog Rattus norvegicus (Rat) NA NA 45571 XM_029356363.2 1157 892 482 2249 1220 P26630 5.86e-91 Paired box protein Pax-6 (Pax[Zf-a]) Danio rerio (Zebrafish) (Brachydanio rerio) anatomical structure development [GO:0048856]; anterior/posterior pattern specification [GO:0009952]; epithalamus development [GO:0021538]; forebrain development [GO:0030900]; habenula development [GO:0021986]; hindbrain development [GO:0030902]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression [GO:0010468]; regulation of transcription by RNA polymerase II [GO:0006357]; retinal cone cell differentiation [GO:0042670]; retinal rod cell differentiation [GO:0060221] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0008284; GO:0009952; GO:0010468; GO:0021538; GO:0021986; GO:0030900; GO:0030902; GO:0042670; GO:0043565; GO:0045944; GO:0048856; GO:0060221 45572 XM_029344232.2 1143 900 883 824 729 Q5RDY7 8.62e-171 Guanine nucleotide-binding protein subunit beta-5 (Gbeta5) (Transducin beta chain 5) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) dopamine receptor signaling pathway [GO:0007212]; negative regulation of voltage-gated calcium channel activity [GO:1901386] GO:0007212; GO:0016020; GO:0031682; GO:0051087; GO:1901386 45573 XM_029339018.2 0 0 0 0 23 NA NA NA NA NA NA 45574 XM_044311684.1 7 0 0 0 0 NA NA NA NA NA NA 45575 XR_006392732.1 94 16 0 62 41 NA NA NA NA NA NA 45576 XM_044313619.1 161 330 231 270 208 NA NA NA NA NA NA 45577 XM_044326914.1 49 15 14 0 27 NA NA NA NA NA NA 45578 XM_044317245.1 5 0 135 4 34 NA NA NA NA NA NA 45579 XM_029334113.2 19 38 111 48 123 NA NA NA NA NA NA 45580 XM_044313541.1 6 22 29 94 3 NA NA NA NA NA NA 45581 XM_044311570.1 1 0 0 0 12 NA NA NA NA NA NA 45582 XR_003827681.2 5939 13874 8551 10059 7350 NA NA NA NA NA NA 45583 XM_044307592.1 4 0 1 23 0 NA NA NA NA NA NA 45584 XR_006397950.1 112 56 7 49 47 NA NA NA NA NA NA 45585 XM_029354807.2 415 339 237 320 218 P59046 1.71e-36 NACHT, LRR and PYD domains-containing protein 12 (Monarch-1) (PYRIN-containing APAF1-like protein 7) (Regulated by nitric oxide) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cellular response to cytokine stimulus [GO:0071345]; dendritic cell migration [GO:0036336]; ERK1 and ERK2 cascade [GO:0070371]; negative regulation of cytokine production [GO:0001818]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of signal transduction [GO:0009968]; negative regulation of Toll signaling pathway [GO:0045751]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of inflammatory response [GO:0050727]; regulation of interleukin-18 production [GO:0032661]; signal transduction [GO:0007165] GO:0001818; GO:0005524; GO:0005737; GO:0005829; GO:0006919; GO:0007165; GO:0008656; GO:0009968; GO:0031953; GO:0032088; GO:0032661; GO:0032692; GO:0032715; GO:0032731; GO:0036336; GO:0038061; GO:0043122; GO:0043124; GO:0043281; GO:0045345; GO:0045751; GO:0050727; GO:0050728; GO:0050729; GO:0070371; GO:0070373; GO:0071345; GO:1901223; GO:1901224 45586 XM_044328867.1 0 0 4 0 8 NA NA NA NA NA NA 45587 XM_029350516.2 16 18 7 29 38 NA NA NA NA NA NA 45588 XM_044312150.1 7 22 9 40 14 NA NA NA NA NA NA 45589 XM_029358140.2 797 669 517 861 854 Q9UBI9 6.93e-53 Headcase protein homolog (hHDC) Homo sapiens (Human) negative regulation of mitotic cell cycle [GO:0045930]; respiratory tube development [GO:0030323] GO:0005634; GO:0005737; GO:0016020; GO:0030323; GO:0045930 45590 XM_029358140.2 797 669 517 861 854 Q9UBI9 3.88e-22 Headcase protein homolog (hHDC) Homo sapiens (Human) negative regulation of mitotic cell cycle [GO:0045930]; respiratory tube development [GO:0030323] GO:0005634; GO:0005737; GO:0016020; GO:0030323; GO:0045930 45591 XM_029351576.2 167 154 19 79 78 Q9WU25 4.25e-32 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) Cavia porcellus (Guinea pig) positive regulation of MAPK cascade [GO:0043410]; regulation of cardiac muscle contraction [GO:0055117]; regulation of vasoconstriction [GO:0019229] GO:0004937; GO:0005634; GO:0005737; GO:0005886; GO:0005901; GO:0019229; GO:0031965; GO:0043410; GO:0046982; GO:0055117 45592 XM_044318594.1 370 187 21 140 151 Q9D6Y9 0 1,4-alpha-glucan-branching enzyme (EC 2.4.1.18) (Brancher enzyme) (Glycogen-branching enzyme) Mus musculus (Mouse) carbohydrate metabolic process [GO:0005975]; glycogen biosynthetic process [GO:0005978]; negative regulation of neuron apoptotic process [GO:0043524] GO:0003844; GO:0004553; GO:0005737; GO:0005829; GO:0005975; GO:0005978; GO:0030246; GO:0043169; GO:0043524; GO:0102752 45593 XM_044329126.1 0 0 4 0 8 NA NA NA NA NA NA 45594 XM_044311155.1 4 1 22 0 29 A7SPX9 7.74e-43 Eukaryotic translation initiation factor 3 subunit M (eIF3m) Nematostella vectensis (Starlet sea anemone) cytoplasmic translational initiation [GO:0002183]; formation of cytoplasmic translation initiation complex [GO:0001732] GO:0001732; GO:0002183; GO:0003743; GO:0005852; GO:0016282; GO:0033290; GO:0071541 45595 XM_029337150.2 7515 4710 4037 6041 4462 P28799 1.68e-105 Progranulin (PGRN) (Acrogranin) (Epithelin precursor) (Glycoprotein of 88 Kda) (GP88) (Glycoprotein 88) (Granulin precursor) (PC cell-derived growth factor) (PCDGF) (Proepithelin) (PEPI) [Cleaved into: Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Epithelin-2) (Granulin B); Granulin-4 (Epithelin-1) (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)] Homo sapiens (Human) astrocyte activation involved in immune response [GO:0002265]; lysosomal lumen acidification [GO:0007042]; lysosomal transport [GO:0007041]; lysosome organization [GO:0007040]; microglial cell activation involved in immune response [GO:0002282]; negative regulation of microglial cell activation [GO:1903979]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neutrophil activation [GO:1902564]; negative regulation of respiratory burst involved in inflammatory response [GO:0060266]; positive regulation of angiogenesis [GO:0045766]; positive regulation of aspartic-type peptidase activity [GO:1905247]; positive regulation of axon regeneration [GO:0048680]; positive regulation of cell migration [GO:0030335]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of inflammatory response to wounding [GO:0106016]; positive regulation of lysosome organization [GO:1905673]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein folding [GO:1903334]; protein stabilization [GO:0050821]; regulation of inflammatory response [GO:0050727]; signal transduction [GO:0007165] GO:0002265; GO:0002282; GO:0003723; GO:0005125; GO:0005576; GO:0005615; GO:0005764; GO:0005765; GO:0005768; GO:0005770; GO:0005783; GO:0005794; GO:0005802; GO:0005886; GO:0007040; GO:0007041; GO:0007042; GO:0007165; GO:0008083; GO:0010595; GO:0016020; GO:0030335; GO:0035578; GO:0043524; GO:0043525; GO:0045766; GO:0048680; GO:0050679; GO:0050727; GO:0050821; GO:0051087; GO:0060266; GO:0070062; GO:0106016; GO:1900426; GO:1902564; GO:1903334; GO:1903979; GO:1905247; GO:1905673 45596 XM_029337150.2 7515 4710 4037 6041 4462 P28799 3.68e-100 Progranulin (PGRN) (Acrogranin) (Epithelin precursor) (Glycoprotein of 88 Kda) (GP88) (Glycoprotein 88) (Granulin precursor) (PC cell-derived growth factor) (PCDGF) (Proepithelin) (PEPI) [Cleaved into: Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Epithelin-2) (Granulin B); Granulin-4 (Epithelin-1) (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)] Homo sapiens (Human) astrocyte activation involved in immune response [GO:0002265]; lysosomal lumen acidification [GO:0007042]; lysosomal transport [GO:0007041]; lysosome organization [GO:0007040]; microglial cell activation involved in immune response [GO:0002282]; negative regulation of microglial cell activation [GO:1903979]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neutrophil activation [GO:1902564]; negative regulation of respiratory burst involved in inflammatory response [GO:0060266]; positive regulation of angiogenesis [GO:0045766]; positive regulation of aspartic-type peptidase activity [GO:1905247]; positive regulation of axon regeneration [GO:0048680]; positive regulation of cell migration [GO:0030335]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of inflammatory response to wounding [GO:0106016]; positive regulation of lysosome organization [GO:1905673]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein folding [GO:1903334]; protein stabilization [GO:0050821]; regulation of inflammatory response [GO:0050727]; signal transduction [GO:0007165] GO:0002265; GO:0002282; GO:0003723; GO:0005125; GO:0005576; GO:0005615; GO:0005764; GO:0005765; GO:0005768; GO:0005770; GO:0005783; GO:0005794; GO:0005802; GO:0005886; GO:0007040; GO:0007041; GO:0007042; GO:0007165; GO:0008083; GO:0010595; GO:0016020; GO:0030335; GO:0035578; GO:0043524; GO:0043525; GO:0045766; GO:0048680; GO:0050679; GO:0050727; GO:0050821; GO:0051087; GO:0060266; GO:0070062; GO:0106016; GO:1900426; GO:1902564; GO:1903334; GO:1903979; GO:1905247; GO:1905673 45597 XM_029337150.2 7515 4710 4037 6041 4462 P28799 1.44e-96 Progranulin (PGRN) (Acrogranin) (Epithelin precursor) (Glycoprotein of 88 Kda) (GP88) (Glycoprotein 88) (Granulin precursor) (PC cell-derived growth factor) (PCDGF) (Proepithelin) (PEPI) [Cleaved into: Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Epithelin-2) (Granulin B); Granulin-4 (Epithelin-1) (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)] Homo sapiens (Human) astrocyte activation involved in immune response [GO:0002265]; lysosomal lumen acidification [GO:0007042]; lysosomal transport [GO:0007041]; lysosome organization [GO:0007040]; microglial cell activation involved in immune response [GO:0002282]; negative regulation of microglial cell activation [GO:1903979]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neutrophil activation [GO:1902564]; negative regulation of respiratory burst involved in inflammatory response [GO:0060266]; positive regulation of angiogenesis [GO:0045766]; positive regulation of aspartic-type peptidase activity [GO:1905247]; positive regulation of axon regeneration [GO:0048680]; positive regulation of cell migration [GO:0030335]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of inflammatory response to wounding [GO:0106016]; positive regulation of lysosome organization [GO:1905673]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein folding [GO:1903334]; protein stabilization [GO:0050821]; regulation of inflammatory response [GO:0050727]; signal transduction [GO:0007165] GO:0002265; GO:0002282; GO:0003723; GO:0005125; GO:0005576; GO:0005615; GO:0005764; GO:0005765; GO:0005768; GO:0005770; GO:0005783; GO:0005794; GO:0005802; GO:0005886; GO:0007040; GO:0007041; GO:0007042; GO:0007165; GO:0008083; GO:0010595; GO:0016020; GO:0030335; GO:0035578; GO:0043524; GO:0043525; GO:0045766; GO:0048680; GO:0050679; GO:0050727; GO:0050821; GO:0051087; GO:0060266; GO:0070062; GO:0106016; GO:1900426; GO:1902564; GO:1903334; GO:1903979; GO:1905247; GO:1905673 45598 XM_029337150.2 7515 4710 4037 6041 4462 P28799 9.47e-90 Progranulin (PGRN) (Acrogranin) (Epithelin precursor) (Glycoprotein of 88 Kda) (GP88) (Glycoprotein 88) (Granulin precursor) (PC cell-derived growth factor) (PCDGF) (Proepithelin) (PEPI) [Cleaved into: Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Epithelin-2) (Granulin B); Granulin-4 (Epithelin-1) (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)] Homo sapiens (Human) astrocyte activation involved in immune response [GO:0002265]; lysosomal lumen acidification [GO:0007042]; lysosomal transport [GO:0007041]; lysosome organization [GO:0007040]; microglial cell activation involved in immune response [GO:0002282]; negative regulation of microglial cell activation [GO:1903979]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neutrophil activation [GO:1902564]; negative regulation of respiratory burst involved in inflammatory response [GO:0060266]; positive regulation of angiogenesis [GO:0045766]; positive regulation of aspartic-type peptidase activity [GO:1905247]; positive regulation of axon regeneration [GO:0048680]; positive regulation of cell migration [GO:0030335]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of inflammatory response to wounding [GO:0106016]; positive regulation of lysosome organization [GO:1905673]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein folding [GO:1903334]; protein stabilization [GO:0050821]; regulation of inflammatory response [GO:0050727]; signal transduction [GO:0007165] GO:0002265; GO:0002282; GO:0003723; GO:0005125; GO:0005576; GO:0005615; GO:0005764; GO:0005765; GO:0005768; GO:0005770; GO:0005783; GO:0005794; GO:0005802; GO:0005886; GO:0007040; GO:0007041; GO:0007042; GO:0007165; GO:0008083; GO:0010595; GO:0016020; GO:0030335; GO:0035578; GO:0043524; GO:0043525; GO:0045766; GO:0048680; GO:0050679; GO:0050727; GO:0050821; GO:0051087; GO:0060266; GO:0070062; GO:0106016; GO:1900426; GO:1902564; GO:1903334; GO:1903979; GO:1905247; GO:1905673 45599 XM_029337150.2 7515 4710 4037 6041 4462 P28799 2.18e-89 Progranulin (PGRN) (Acrogranin) (Epithelin precursor) (Glycoprotein of 88 Kda) (GP88) (Glycoprotein 88) (Granulin precursor) (PC cell-derived growth factor) (PCDGF) (Proepithelin) (PEPI) [Cleaved into: Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Epithelin-2) (Granulin B); Granulin-4 (Epithelin-1) (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)] Homo sapiens (Human) astrocyte activation involved in immune response [GO:0002265]; lysosomal lumen acidification [GO:0007042]; lysosomal transport [GO:0007041]; lysosome organization [GO:0007040]; microglial cell activation involved in immune response [GO:0002282]; negative regulation of microglial cell activation [GO:1903979]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neutrophil activation [GO:1902564]; negative regulation of respiratory burst involved in inflammatory response [GO:0060266]; positive regulation of angiogenesis [GO:0045766]; positive regulation of aspartic-type peptidase activity [GO:1905247]; positive regulation of axon regeneration [GO:0048680]; positive regulation of cell migration [GO:0030335]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of inflammatory response to wounding [GO:0106016]; positive regulation of lysosome organization [GO:1905673]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein folding [GO:1903334]; protein stabilization [GO:0050821]; regulation of inflammatory response [GO:0050727]; signal transduction [GO:0007165] GO:0002265; GO:0002282; GO:0003723; GO:0005125; GO:0005576; GO:0005615; GO:0005764; GO:0005765; GO:0005768; GO:0005770; GO:0005783; GO:0005794; GO:0005802; GO:0005886; GO:0007040; GO:0007041; GO:0007042; GO:0007165; GO:0008083; GO:0010595; GO:0016020; GO:0030335; GO:0035578; GO:0043524; GO:0043525; GO:0045766; GO:0048680; GO:0050679; GO:0050727; GO:0050821; GO:0051087; GO:0060266; GO:0070062; GO:0106016; GO:1900426; GO:1902564; GO:1903334; GO:1903979; GO:1905247; GO:1905673 45600 XM_029337150.2 7515 4710 4037 6041 4462 P28799 1.82e-88 Progranulin (PGRN) (Acrogranin) (Epithelin precursor) (Glycoprotein of 88 Kda) (GP88) (Glycoprotein 88) (Granulin precursor) (PC cell-derived growth factor) (PCDGF) (Proepithelin) (PEPI) [Cleaved into: Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Epithelin-2) (Granulin B); Granulin-4 (Epithelin-1) (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)] Homo sapiens (Human) astrocyte activation involved in immune response [GO:0002265]; lysosomal lumen acidification [GO:0007042]; lysosomal transport [GO:0007041]; lysosome organization [GO:0007040]; microglial cell activation involved in immune response [GO:0002282]; negative regulation of microglial cell activation [GO:1903979]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neutrophil activation [GO:1902564]; negative regulation of respiratory burst involved in inflammatory response [GO:0060266]; positive regulation of angiogenesis [GO:0045766]; positive regulation of aspartic-type peptidase activity [GO:1905247]; positive regulation of axon regeneration [GO:0048680]; positive regulation of cell migration [GO:0030335]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of inflammatory response to wounding [GO:0106016]; positive regulation of lysosome organization [GO:1905673]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein folding [GO:1903334]; protein stabilization [GO:0050821]; regulation of inflammatory response [GO:0050727]; signal transduction [GO:0007165] GO:0002265; GO:0002282; GO:0003723; GO:0005125; GO:0005576; GO:0005615; GO:0005764; GO:0005765; GO:0005768; GO:0005770; GO:0005783; GO:0005794; GO:0005802; GO:0005886; GO:0007040; GO:0007041; GO:0007042; GO:0007165; GO:0008083; GO:0010595; GO:0016020; GO:0030335; GO:0035578; GO:0043524; GO:0043525; GO:0045766; GO:0048680; GO:0050679; GO:0050727; GO:0050821; GO:0051087; GO:0060266; GO:0070062; GO:0106016; GO:1900426; GO:1902564; GO:1903334; GO:1903979; GO:1905247; GO:1905673 45601 XM_029337150.2 7515 4710 4037 6041 4462 P28799 3.7e-75 Progranulin (PGRN) (Acrogranin) (Epithelin precursor) (Glycoprotein of 88 Kda) (GP88) (Glycoprotein 88) (Granulin precursor) (PC cell-derived growth factor) (PCDGF) (Proepithelin) (PEPI) [Cleaved into: Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Epithelin-2) (Granulin B); Granulin-4 (Epithelin-1) (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)] Homo sapiens (Human) astrocyte activation involved in immune response [GO:0002265]; lysosomal lumen acidification [GO:0007042]; lysosomal transport [GO:0007041]; lysosome organization [GO:0007040]; microglial cell activation involved in immune response [GO:0002282]; negative regulation of microglial cell activation [GO:1903979]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neutrophil activation [GO:1902564]; negative regulation of respiratory burst involved in inflammatory response [GO:0060266]; positive regulation of angiogenesis [GO:0045766]; positive regulation of aspartic-type peptidase activity [GO:1905247]; positive regulation of axon regeneration [GO:0048680]; positive regulation of cell migration [GO:0030335]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of inflammatory response to wounding [GO:0106016]; positive regulation of lysosome organization [GO:1905673]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein folding [GO:1903334]; protein stabilization [GO:0050821]; regulation of inflammatory response [GO:0050727]; signal transduction [GO:0007165] GO:0002265; GO:0002282; GO:0003723; GO:0005125; GO:0005576; GO:0005615; GO:0005764; GO:0005765; GO:0005768; GO:0005770; GO:0005783; GO:0005794; GO:0005802; GO:0005886; GO:0007040; GO:0007041; GO:0007042; GO:0007165; GO:0008083; GO:0010595; GO:0016020; GO:0030335; GO:0035578; GO:0043524; GO:0043525; GO:0045766; GO:0048680; GO:0050679; GO:0050727; GO:0050821; GO:0051087; GO:0060266; GO:0070062; GO:0106016; GO:1900426; GO:1902564; GO:1903334; GO:1903979; GO:1905247; GO:1905673 45602 XM_029337150.2 7515 4710 4037 6041 4462 P28799 2.16e-68 Progranulin (PGRN) (Acrogranin) (Epithelin precursor) (Glycoprotein of 88 Kda) (GP88) (Glycoprotein 88) (Granulin precursor) (PC cell-derived growth factor) (PCDGF) (Proepithelin) (PEPI) [Cleaved into: Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Epithelin-2) (Granulin B); Granulin-4 (Epithelin-1) (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)] Homo sapiens (Human) astrocyte activation involved in immune response [GO:0002265]; lysosomal lumen acidification [GO:0007042]; lysosomal transport [GO:0007041]; lysosome organization [GO:0007040]; microglial cell activation involved in immune response [GO:0002282]; negative regulation of microglial cell activation [GO:1903979]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neutrophil activation [GO:1902564]; negative regulation of respiratory burst involved in inflammatory response [GO:0060266]; positive regulation of angiogenesis [GO:0045766]; positive regulation of aspartic-type peptidase activity [GO:1905247]; positive regulation of axon regeneration [GO:0048680]; positive regulation of cell migration [GO:0030335]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of inflammatory response to wounding [GO:0106016]; positive regulation of lysosome organization [GO:1905673]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein folding [GO:1903334]; protein stabilization [GO:0050821]; regulation of inflammatory response [GO:0050727]; signal transduction [GO:0007165] GO:0002265; GO:0002282; GO:0003723; GO:0005125; GO:0005576; GO:0005615; GO:0005764; GO:0005765; GO:0005768; GO:0005770; GO:0005783; GO:0005794; GO:0005802; GO:0005886; GO:0007040; GO:0007041; GO:0007042; GO:0007165; GO:0008083; GO:0010595; GO:0016020; GO:0030335; GO:0035578; GO:0043524; GO:0043525; GO:0045766; GO:0048680; GO:0050679; GO:0050727; GO:0050821; GO:0051087; GO:0060266; GO:0070062; GO:0106016; GO:1900426; GO:1902564; GO:1903334; GO:1903979; GO:1905247; GO:1905673 45603 XM_029337150.2 7515 4710 4037 6041 4462 P28799 8.39e-52 Progranulin (PGRN) (Acrogranin) (Epithelin precursor) (Glycoprotein of 88 Kda) (GP88) (Glycoprotein 88) (Granulin precursor) (PC cell-derived growth factor) (PCDGF) (Proepithelin) (PEPI) [Cleaved into: Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Epithelin-2) (Granulin B); Granulin-4 (Epithelin-1) (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)] Homo sapiens (Human) astrocyte activation involved in immune response [GO:0002265]; lysosomal lumen acidification [GO:0007042]; lysosomal transport [GO:0007041]; lysosome organization [GO:0007040]; microglial cell activation involved in immune response [GO:0002282]; negative regulation of microglial cell activation [GO:1903979]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neutrophil activation [GO:1902564]; negative regulation of respiratory burst involved in inflammatory response [GO:0060266]; positive regulation of angiogenesis [GO:0045766]; positive regulation of aspartic-type peptidase activity [GO:1905247]; positive regulation of axon regeneration [GO:0048680]; positive regulation of cell migration [GO:0030335]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of inflammatory response to wounding [GO:0106016]; positive regulation of lysosome organization [GO:1905673]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein folding [GO:1903334]; protein stabilization [GO:0050821]; regulation of inflammatory response [GO:0050727]; signal transduction [GO:0007165] GO:0002265; GO:0002282; GO:0003723; GO:0005125; GO:0005576; GO:0005615; GO:0005764; GO:0005765; GO:0005768; GO:0005770; GO:0005783; GO:0005794; GO:0005802; GO:0005886; GO:0007040; GO:0007041; GO:0007042; GO:0007165; GO:0008083; GO:0010595; GO:0016020; GO:0030335; GO:0035578; GO:0043524; GO:0043525; GO:0045766; GO:0048680; GO:0050679; GO:0050727; GO:0050821; GO:0051087; GO:0060266; GO:0070062; GO:0106016; GO:1900426; GO:1902564; GO:1903334; GO:1903979; GO:1905247; GO:1905673 45604 XM_029329232.2 100 0 0 94 61 P29054 1.82e-157 Transcription initiation factor IIB (EC 2.3.1.48) (General transcription factor TFIIB) Xenopus laevis (African clawed frog) protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription by RNA polymerase II [GO:0006366]; transcription initiation at RNA polymerase II promoter [GO:0006367]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; viral transcription [GO:0019083] GO:0000979; GO:0000993; GO:0001174; GO:0004402; GO:0005634; GO:0005694; GO:0006366; GO:0006367; GO:0006473; GO:0008270; GO:0016407; GO:0017025; GO:0019083; GO:0032993; GO:0051123; GO:1990114; GO:1990841 45605 XM_029349622.2 20 19 6 1 210 NA NA NA NA NA NA 45606 XM_029343609.2 8 4 14 0 46 NA NA NA NA NA NA 45607 XM_044321868.1 18 17 7 26 29 O75762 1.3e-98 Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation-sensitive protein p120) (p120) (Wasabi receptor) Homo sapiens (Human) calcium ion transmembrane transport [GO:0070588]; cell surface receptor signaling pathway [GO:0007166]; cellular calcium ion homeostasis [GO:0006874]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to organic substance [GO:0071310]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; ion transport [GO:0006811]; protein homotetramerization [GO:0051289]; response to cold [GO:0009409]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; sensory perception of pain [GO:0019233]; thermoception [GO:0050955] GO:0005262; GO:0005886; GO:0006811; GO:0006874; GO:0007166; GO:0009409; GO:0009410; GO:0010033; GO:0014070; GO:0015267; GO:0015278; GO:0019233; GO:0032421; GO:0042802; GO:0048265; GO:0050955; GO:0050966; GO:0050968; GO:0051289; GO:0070301; GO:0070588; GO:0071310; GO:0097604 45608 XM_029336354.2 43 26 9 34 28 NA NA NA NA NA NA 45609 XM_029349634.2 0 0 93 79 38 NA NA NA NA NA NA 45610 XR_003825710.2 34 26 10 37 51 NA NA NA NA NA NA 45611 XM_029343593.2 94 0 143 113 49 NA NA NA NA NA NA 45612 XM_044317103.1 29 0 88 22 135 NA NA NA NA NA NA 45613 XM_029335153.2 2540 1627 688 3014 3121 Q8K4Q0 0 Regulatory-associated protein of mTOR (Raptor) (p150 target of rapamycin (TOR)-scaffold protein) Mus musculus (Mouse) cellular response to amino acid stimulus [GO:0071230]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hypoxia [GO:0071456]; cellular response to leucine [GO:0071233]; cellular response to nutrient levels [GO:0031669]; cellular response to osmotic stress [GO:0071470]; cellular response to starvation [GO:0009267]; negative regulation of autophagy [GO:0010507]; negative regulation of insulin secretion [GO:0046676]; phosphorylation [GO:0016310]; positive regulation of cell growth [GO:0030307]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of glycolytic process [GO:0045821]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of pentose-phosphate shunt [GO:1905857]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of TOR signaling [GO:0032008]; positive regulation of transcription by RNA polymerase III [GO:0045945]; regulation of autophagy [GO:0010506]; regulation of cell growth [GO:0001558]; regulation of cell size [GO:0008361]; regulation of phosphorylation [GO:0042325]; regulation of protein phosphorylation [GO:0001932]; response to xenobiotic stimulus [GO:0009410]; social behavior [GO:0035176]; TOR signaling [GO:0031929]; TORC1 signaling [GO:0038202] GO:0001002; GO:0001003; GO:0001006; GO:0001156; GO:0001558; GO:0001932; GO:0001938; GO:0005654; GO:0005737; GO:0005764; GO:0005829; GO:0006974; GO:0008361; GO:0009267; GO:0009410; GO:0010494; GO:0010506; GO:0010507; GO:0010800; GO:0016310; GO:0019901; GO:0030291; GO:0030295; GO:0030307; GO:0030425; GO:0030674; GO:0031669; GO:0031929; GO:0031931; GO:0032008; GO:0033138; GO:0035176; GO:0038202; GO:0042325; GO:0043025; GO:0044877; GO:0045821; GO:0045945; GO:0046676; GO:0046889; GO:0071230; GO:0071233; GO:0071456; GO:0071470; GO:0071889; GO:0071902; GO:1900087; GO:1905857 45614 XM_029343286.2 803 933 120 276 141 NA NA NA NA NA NA 45615 XM_044319877.1 551 306 164 243 65 Q9QZ85 1.06e-50 Interferon-inducible GTPase 1 (EC 3.6.5.-) Mus musculus (Mouse) cellular response to interferon-beta [GO:0035458]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; regulation of autophagy [GO:0010506]; response to bacterium [GO:0009617] GO:0003924; GO:0005525; GO:0005737; GO:0005789; GO:0006952; GO:0009617; GO:0010506; GO:0019003; GO:0019221; GO:0020005; GO:0031965; GO:0032580; GO:0035458; GO:0042802; GO:0042832; GO:0045087; GO:0050829 45616 XM_029339424.2 37 47 0 18 0 Q7T163 0 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 45617 XM_029339424.2 37 47 0 18 0 Q7T163 3.82e-42 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 45618 XM_029339424.2 37 47 0 18 0 Q7T163 4.3e-33 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 45619 XM_029339424.2 37 47 0 18 0 Q7T163 2.59e-29 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 45620 XM_029339424.2 37 47 0 18 0 Q7T163 6.98e-27 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 45621 XM_029339424.2 37 47 0 18 0 Q7T163 1.27e-22 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 45622 XM_044307322.1 8 22 12 45 3 NA NA NA NA NA NA 45623 XM_029326340.2 191 325 307 363 566 NA NA NA NA NA NA 45624 XM_029353311.2 1 0 16 0 2 P51954 3.24e-86 Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase 1) (NimA-related protein kinase 1) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; cilium assembly [GO:0060271]; kidney development [GO:0001822]; multicellular organism growth [GO:0035264]; protein phosphorylation [GO:0006468]; regulation of DNA damage checkpoint [GO:2000001]; response to ionizing radiation [GO:0010212]; spermatogenesis [GO:0007283] GO:0000242; GO:0001822; GO:0004672; GO:0004674; GO:0004713; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0005829; GO:0006468; GO:0006974; GO:0007049; GO:0007283; GO:0010212; GO:0016301; GO:0034451; GO:0035264; GO:0046872; GO:0051301; GO:0060271; GO:0071889; GO:0106310; GO:2000001 45625 XM_044308080.1 0 42 0 0 0 Q0E908 5.49e-39 Hillarin (D-Hillarin) (D-hil) Drosophila melanogaster (Fruit fly) NA GO:0005938; GO:0032154; GO:0046872 45626 XM_029344901.2 106 29 10 52 64 NA NA NA NA NA NA 45627 XM_044308394.1 2446 2497 1946 1578 2195 Q16774 2.81e-67 Guanylate kinase (EC 2.7.4.8) (GMP kinase) (Guanylate kinase 1) Homo sapiens (Human) dGDP biosynthetic process [GO:0006185]; nucleobase-containing small molecule interconversion [GO:0015949]; phosphorylation [GO:0016310]; purine nucleotide metabolic process [GO:0006163]; xenobiotic metabolic process [GO:0006805] GO:0001917; GO:0004385; GO:0005524; GO:0005829; GO:0006163; GO:0006185; GO:0006805; GO:0015949; GO:0016310 45628 XR_006392640.1 12 88 38 6 26 NA NA NA NA NA NA 45629 XM_044320498.1 0 917 0 450 1815 D3ZGB1 7.2e-33 Nuclear factor of activated T-cells 5 (NF-AT5) (T-cell transcription factor NFAT5) Rattus norvegicus (Rat) calcineurin-NFAT signaling cascade [GO:0033173]; cellular response to cytokine stimulus [GO:0071345]; cellular response to DNA damage stimulus [GO:0006974]; positive regulation of gene expression [GO:0010628]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R-loop processing [GO:0062176]; regulation of calcineurin-NFAT signaling cascade [GO:0070884]; regulation of transcription by RNA polymerase II [GO:0006357]; response to osmotic stress [GO:0006970] GO:0000978; GO:0000981; GO:0001228; GO:0003677; GO:0003682; GO:0005634; GO:0005654; GO:0005667; GO:0005694; GO:0005737; GO:0005829; GO:0006357; GO:0006970; GO:0006974; GO:0010628; GO:0033173; GO:0045944; GO:0062176; GO:0070884; GO:0071345; GO:1901224; GO:1904996; GO:1990837 45630 XM_029357962.2 45 7 54 82 31 NA NA NA NA NA NA 45631 XM_044328895.1 100 75 121 58 122 NA NA NA NA NA NA 45632 XM_029342721.2 185 106 28 119 119 Q6ZN57 1.61e-53 Zinc finger protein ZFP2 (Zfp-2) (Zinc finger protein 751) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 45633 XM_029342721.2 185 106 28 119 119 Q6ZN57 5.66e-49 Zinc finger protein ZFP2 (Zfp-2) (Zinc finger protein 751) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 45634 XM_029342721.2 185 106 28 119 119 Q6ZN57 2.93e-48 Zinc finger protein ZFP2 (Zfp-2) (Zinc finger protein 751) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 45635 XM_029342721.2 185 106 28 119 119 Q6ZN57 4.74e-48 Zinc finger protein ZFP2 (Zfp-2) (Zinc finger protein 751) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 45636 XM_029342721.2 185 106 28 119 119 Q6ZN57 2.19e-47 Zinc finger protein ZFP2 (Zfp-2) (Zinc finger protein 751) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 45637 XM_029342721.2 185 106 28 119 119 Q6ZN57 1.21e-45 Zinc finger protein ZFP2 (Zfp-2) (Zinc finger protein 751) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 45638 XM_029342721.2 185 106 28 119 119 Q6ZN57 2.92e-41 Zinc finger protein ZFP2 (Zfp-2) (Zinc finger protein 751) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 45639 XM_044309429.1 29 18 55 12 68 NA NA NA NA NA NA 45640 XM_044325898.1 139 71 79 113 120 NA NA NA NA NA NA 45641 XM_044309816.1 7 0 19 4 58 P10079 2.33e-162 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 45642 XM_044309816.1 7 0 19 4 58 P10079 3.01e-161 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 45643 XM_044309816.1 7 0 19 4 58 P10079 2.39e-159 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 45644 XM_044309816.1 7 0 19 4 58 P10079 7.83e-159 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 45645 XM_044309816.1 7 0 19 4 58 P10079 1.14e-156 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 45646 XM_044309816.1 7 0 19 4 58 P10079 5.56e-154 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 45647 XM_044309816.1 7 0 19 4 58 P10079 7.59e-153 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 45648 XM_044309816.1 7 0 19 4 58 P10079 3.94e-136 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 45649 XM_044309816.1 7 0 19 4 58 P10079 1.33e-114 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 45650 XM_029329578.2 37 360 41 47 30 A4IGL7 3.94e-90 Peroxidasin (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0005576; GO:0005604; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0031012; GO:0042744; GO:0046872; GO:0051260; GO:0070207; GO:0070831; GO:0071711; GO:0140825 45651 XM_029335238.2 2663 2313 1751 2656 1990 Q924T7 2.23e-116 E3 ubiquitin-protein ligase RNF31 (EC 2.3.2.31) (HOIL-1-interacting protein) (HOIP) (Putative Ariadne-like ubiquitin ligase) (PAUL) (RING finger protein 31) (RING-type E3 ubiquitin transferase RNF31) Mus musculus (Mouse) CD40 signaling pathway [GO:0023035]; defense response to bacterium [GO:0042742]; negative regulation of necroptotic process [GO:0060546]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of xenophagy [GO:1904417]; protein linear polyubiquitination [GO:0097039]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; T cell receptor signaling pathway [GO:0050852] GO:0000209; GO:0004842; GO:0005829; GO:0009898; GO:0016567; GO:0023035; GO:0031625; GO:0035631; GO:0036435; GO:0042742; GO:0042802; GO:0043123; GO:0043130; GO:0046872; GO:0050852; GO:0051092; GO:0060546; GO:0061630; GO:0070530; GO:0071797; GO:0097039; GO:1904417; GO:1990450 45652 XM_044312025.1 0 0 9 0 4 NA NA NA NA NA NA 45653 XR_006395655.1 42 118 23 91 46 NA NA NA NA NA NA 45654 XM_044326058.1 26 6 4 7 6 NA NA NA NA NA NA 45655 XM_029355752.2 54 63 51 68 510 R1CW23 1.57e-91 Dimethylsulfonioproprionate lyase 7 (DMSP lyase 7) (EC 4.4.1.3) (Dimethylpropiothetin dethiomethylase 7) Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi) NA GO:0047869 45656 XM_029356660.2 2633 2087 1251 1866 2047 Q54BU4 0 ABC transporter B family member 1 (ABC transporter ABCB.1) Dictyostelium discoideum (Social amoeba) chemotaxis [GO:0006935]; culmination involved in sorocarp development [GO:0031154]; hyperosmotic response [GO:0006972]; transmembrane transport [GO:0055085] GO:0005524; GO:0006935; GO:0006972; GO:0016020; GO:0016887; GO:0031154; GO:0042626; GO:0055085; GO:0140359 45657 XM_029337892.2 10 18 53 23 0 Q6BZW3 2.58e-25 Protein BTN1 Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica) L-arginine transmembrane transport [GO:1903826]; lysine transport [GO:0015819]; regulation of intracellular pH [GO:0051453] GO:0000324; GO:0005773; GO:0005774; GO:0015819; GO:0022857; GO:0051453; GO:1903826 45658 XM_044325442.1 124 28 60 65 92 G5ECX0 1.05e-28 Latrophilin-like protein LAT-2 Caenorhabditis elegans adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; self proteolysis [GO:0097264] GO:0004175; GO:0004930; GO:0005886; GO:0007166; GO:0007189; GO:0030246; GO:0097264 45659 XM_029339869.2 0 0 0 373 373 NA NA NA NA NA NA 45660 XM_029325492.2 67 163 79 81 83 Q20201 3.05e-29 Transcription factor sox-3 Caenorhabditis elegans anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; neuron differentiation [GO:0030182]; regulation of DNA-templated transcription [GO:0006355] GO:0000978; GO:0000981; GO:0005634; GO:0006355; GO:0009653; GO:0030154; GO:0030182; GO:0043565 45661 XR_006396275.1 19 13 1 63 13 NA NA NA NA NA NA 45662 XM_029351581.2 144 43 73 85 192 Q9IAL2 2.99e-44 Visual system homeobox 1 (Homeobox protein Chx10-1) (Transcription factor VSX1) Gallus gallus (Chicken) neuron development [GO:0048666]; regulation of DNA-templated transcription [GO:0006355]; response to stimulus [GO:0050896]; visual perception [GO:0007601] GO:0000976; GO:0000981; GO:0005634; GO:0006355; GO:0007601; GO:0048666; GO:0050896 45663 XM_029357829.2 2314 2541 1722 1943 2406 Q6DJE4 1.41e-120 Cleavage and polyadenylation specificity factor subunit 5 (Nudix hydrolase 21) Xenopus laevis (African clawed frog) cell differentiation [GO:0030154]; messenger ribonucleoprotein complex assembly [GO:1990120]; mRNA alternative polyadenylation [GO:0110104]; mRNA polyadenylation [GO:0006378]; mRNA processing [GO:0006397]; positive regulation of mRNA cleavage [GO:0031439]; positive regulation of mRNA polyadenylation [GO:1900365]; positive regulation of pro-B cell differentiation [GO:2000975]; positive regulation of stem cell differentiation [GO:2000738]; post-transcriptional regulation of gene expression [GO:0010608]; protein heterotetramerization [GO:0051290] GO:0003729; GO:0005634; GO:0005737; GO:0005849; GO:0006378; GO:0006397; GO:0010608; GO:0030154; GO:0031439; GO:0035925; GO:0042382; GO:0042802; GO:0051290; GO:0110104; GO:1900365; GO:1990120; GO:2000738; GO:2000975 45664 XR_006391536.1 25 0 100 0 0 NA NA NA NA NA NA 45665 XM_029357909.2 195 55 433 497 8 NA NA NA NA NA NA 45666 XM_029349808.2 649 199 341 663 361 Q58A42 2.48e-115 Protein DD3-3 Dictyostelium discoideum (Social amoeba) NA GO:0016020 45667 XM_029349238.2 832 498 445 789 500 Q96FV9 0 THO complex subunit 1 (Tho1) (Nuclear matrix protein p84) (p84N5) (hTREX84) Homo sapiens (Human) apoptotic process [GO:0006915]; mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; negative regulation of DNA damage checkpoint [GO:2000002]; negative regulation of isotype switching to IgA isotypes [GO:0048297]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; regulation of DNA recombination [GO:0000018]; regulation of DNA-templated transcription elongation [GO:0032784]; replication fork processing [GO:0031297]; RNA processing [GO:0006396]; RNA splicing [GO:0008380]; signal transduction [GO:0007165]; viral mRNA export from host cell nucleus [GO:0046784] GO:0000018; GO:0000346; GO:0000347; GO:0000445; GO:0003677; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006396; GO:0006397; GO:0006406; GO:0006915; GO:0007165; GO:0008380; GO:0016363; GO:0016607; GO:0031297; GO:0032784; GO:0032786; GO:0046784; GO:0048297; GO:2000002 45668 XR_006393904.1 41 2 25 5 151 NA NA NA NA NA NA 45669 XM_029338856.2 10626 15539 15949 21051 16768 Q5R5H1 0 S-adenosylmethionine synthase isoform type-2 (AdoMet synthase 2) (EC 2.5.1.6) (Methionine adenosyltransferase 2) (MAT 2) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cellular response to leukemia inhibitory factor [GO:1990830]; one-carbon metabolic process [GO:0006730]; protein heterooligomerization [GO:0051291]; protein hexamerization [GO:0034214]; S-adenosylmethionine biosynthetic process [GO:0006556] GO:0004478; GO:0005524; GO:0006556; GO:0006730; GO:0034214; GO:0042802; GO:0046872; GO:0048269; GO:0051291; GO:1990830 45670 XM_029324601.2 220 115 190 92 151 NA NA NA NA NA NA 45671 XM_029357571.2 32 15 25 58 6 NA NA NA NA NA NA 45672 XM_029348813.2 3758 3414 1289 3022 997 NA NA NA NA NA NA 45673 XM_044316974.1 1306 945 449 0 124 Q6DCV0 3.33e-153 WD repeat domain phosphoinositide-interacting protein 4 (WIPI-4) (WD repeat-containing protein 45) Xenopus laevis (African clawed frog) autophagosome assembly [GO:0000045]; cellular response to starvation [GO:0009267]; positive regulation of autophagosome assembly [GO:2000786] GO:0000045; GO:0000407; GO:0009267; GO:0032266; GO:1901981; GO:2000786 45674 XM_029338509.2 109 47 13 0 213 O08658 6.56e-114 Nuclear pore complex protein Nup88 (88 kDa nucleoporin) (Nucleoporin Nup84) (Nucleoporin Nup88) Rattus norvegicus (Rat) mitotic cell cycle [GO:0000278]; mRNA export from nucleus [GO:0006406]; protein import into nucleus [GO:0006606]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056] GO:0000055; GO:0000056; GO:0000278; GO:0005635; GO:0005643; GO:0005654; GO:0006406; GO:0006606; GO:0017056 45675 XM_029350032.2 4811 3765 3312 6459 4092 Q7Z5K2 5.42e-115 Wings apart-like protein homolog (Friend of EBNA2 protein) (WAPL cohesin release factor) Homo sapiens (Human) cell division [GO:0051301]; mitotic sister chromatid segregation [GO:0000070]; negative regulation of chromatin binding [GO:0035562]; negative regulation of DNA replication [GO:0008156]; negative regulation of sister chromatid cohesion [GO:0045875]; protein localization to chromatin [GO:0071168]; regulation of cohesin loading [GO:0071922] GO:0000070; GO:0000775; GO:0000785; GO:0005634; GO:0005654; GO:0005694; GO:0005737; GO:0005829; GO:0008156; GO:0035562; GO:0043231; GO:0045171; GO:0045875; GO:0051301; GO:0071168; GO:0071922; GO:0072686; GO:0140083 45676 XM_029333391.2 335 269 179 298 293 A0A8M3B525 1.06e-93 NA NA NA NA 45677 XM_029356940.2 27 16 6 24 28 NA NA NA NA NA NA 45678 XM_029341949.2 0 0 0 17 232 Q7YR35 8.75e-165 Guanine nucleotide-binding protein-like 1 Pan troglodytes (Chimpanzee) NA GO:0003924; GO:0005525 45679 XM_029332838.2 920 782 596 878 942 Q810B6 0 Rabankyrin-5 (Rank-5) (Ankyrin repeat and FYVE domain-containing protein 1) (Ankyrin repeats hooked to a zinc finger motif) Mus musculus (Mouse) endocytosis [GO:0006897]; endosomal transport [GO:0016197]; endosomal vesicle fusion [GO:0034058]; Golgi to lysosome transport [GO:0090160]; positive regulation of pinocytosis [GO:0048549]; retrograde transport, endosome to Golgi [GO:0042147] GO:0005768; GO:0005769; GO:0005829; GO:0006897; GO:0010008; GO:0016020; GO:0016197; GO:0030904; GO:0031267; GO:0034058; GO:0042147; GO:0043231; GO:0044354; GO:0046872; GO:0048549; GO:0090160; GO:1901981 45680 XM_029332838.2 920 782 596 878 942 Q810B6 1.69e-138 Rabankyrin-5 (Rank-5) (Ankyrin repeat and FYVE domain-containing protein 1) (Ankyrin repeats hooked to a zinc finger motif) Mus musculus (Mouse) endocytosis [GO:0006897]; endosomal transport [GO:0016197]; endosomal vesicle fusion [GO:0034058]; Golgi to lysosome transport [GO:0090160]; positive regulation of pinocytosis [GO:0048549]; retrograde transport, endosome to Golgi [GO:0042147] GO:0005768; GO:0005769; GO:0005829; GO:0006897; GO:0010008; GO:0016020; GO:0016197; GO:0030904; GO:0031267; GO:0034058; GO:0042147; GO:0043231; GO:0044354; GO:0046872; GO:0048549; GO:0090160; GO:1901981 45681 XM_029342762.2 409 253 293 286 515 Q9Y5Q9 3.15e-163 General transcription factor 3C polypeptide 3 (Transcription factor IIIC 102 kDa subunit) (TFIIIC 102 kDa subunit) (TFIIIC102) (Transcription factor IIIC subunit gamma) (TF3C-gamma) Homo sapiens (Human) 5S class rRNA transcription by RNA polymerase III [GO:0042791]; transcription by RNA polymerase III [GO:0006383]; tRNA transcription by RNA polymerase III [GO:0042797] GO:0000127; GO:0000995; GO:0003677; GO:0005654; GO:0005730; GO:0006383; GO:0031965; GO:0042791; GO:0042797 45682 XM_044318001.1 469 1909 888 858 1401 NA NA NA NA NA NA 45683 XM_029334110.2 298 118 232 313 288 A6H8T2 2.63e-76 Dynein axonemal intermediate chain 7 Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005930; GO:0008017; GO:0048487 45684 XM_029334110.2 298 118 232 313 288 A6H8T2 4.25e-36 Dynein axonemal intermediate chain 7 Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005930; GO:0008017; GO:0048487 45685 XM_044321092.1 294 18 49 19 143 Q8LPL3 3.05e-40 L-ascorbate oxidase (AAO) (AO) (ASO) (Ascorbase) (EC 1.10.3.3) Arabidopsis thaliana (Mouse-ear cress) defense response [GO:0006952]; L-ascorbic acid catabolic process [GO:0019854]; negative regulation of defense response to virus [GO:0050687]; negative regulation of response to salt stress [GO:1901001]; response to hydrogen peroxide [GO:0042542]; response to oxidative stress [GO:0006979]; response to salt stress [GO:0009651]; response to virus [GO:0009615] GO:0005507; GO:0005576; GO:0006952; GO:0006979; GO:0008447; GO:0009536; GO:0009615; GO:0009651; GO:0016491; GO:0019854; GO:0042542; GO:0050687; GO:1901001 45686 XM_044312757.1 60 11 0 50 1 Q6AX80 2.83e-85 Bis(5'-adenosyl)-triphosphatase enpp4 (EC 3.6.1.29) (AP3A hydrolase) (AP3Aase) (Ectonucleotide pyrophosphatase/phosphodiesterase family member 4) (E-NPP 4) (NPP-4) Xenopus laevis (African clawed frog) blood coagulation [GO:0007596] GO:0005886; GO:0007596; GO:0046872; GO:0047710 45687 XM_029325053.2 5 7 0 0 0 NA NA NA NA NA NA 45688 XM_029345437.2 397 292 208 425 418 Q02978 8.02e-154 Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP) (alpha-oxoglutarate carrier) (Solute carrier family 25 member 11) (SLC25A11) Homo sapiens (Human) gluconeogenesis [GO:0006094]; lipid transport [GO:0006869]; malate transmembrane transport [GO:0071423]; oxaloacetate transport [GO:0015729]; phosphate ion transmembrane transport [GO:0035435]; succinate transmembrane transport [GO:0071422]; sulfate transport [GO:0008272]; thiosulfate transport [GO:0015709] GO:0003723; GO:0005634; GO:0005739; GO:0005743; GO:0005886; GO:0006094; GO:0006869; GO:0008272; GO:0015116; GO:0015117; GO:0015131; GO:0015140; GO:0015141; GO:0015297; GO:0015367; GO:0015709; GO:0015729; GO:0022857; GO:0035435; GO:0071422; GO:0071423 45689 XM_044313939.1 29 9 92 31 375 B8VIU6 4.02e-62 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 45690 XM_044321748.1 263 115 141 161 232 Q9NZI7 4.78e-103 Upstream-binding protein 1 (Transcription factor LBP-1) Homo sapiens (Human) angiogenesis [GO:0001525]; negative regulation of viral transcription [GO:0032897]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000785; GO:0000978; GO:0000981; GO:0001228; GO:0001525; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0032897; GO:0045944; GO:1990837 45691 XM_044312966.1 6 43 63 56 72 D4A523 2.99e-44 NACHT, LRR and PYD domains-containing protein 3 (EC 3.6.4.-) Rattus norvegicus (Rat) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptidoglycan [GO:0071224]; cellular response to virus [GO:0098586]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of biotic stimulus [GO:0009595]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; NLRP3 inflammasome complex assembly [GO:0044546]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-13 production [GO:0032736]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-5 production [GO:0032754]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T-helper 17 cell differentiation [GO:2000321]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type 2 immune response [GO:0002830]; protein homooligomerization [GO:0051260]; regulation of inflammatory response [GO:0050727]; response to ethanol [GO:0045471]; response to organic cyclic compound [GO:0014070] GO:0000139; GO:0002523; GO:0002526; GO:0002674; GO:0002720; GO:0002830; GO:0005524; GO:0005576; GO:0005634; GO:0005737; GO:0005739; GO:0005783; GO:0006919; GO:0006954; GO:0009595; GO:0014070; GO:0016020; GO:0016887; GO:0031021; GO:0032088; GO:0032691; GO:0032731; GO:0032736; GO:0032753; GO:0032754; GO:0035591; GO:0042802; GO:0043280; GO:0043531; GO:0043565; GO:0044546; GO:0045087; GO:0045471; GO:0045630; GO:0045944; GO:0050727; GO:0050728; GO:0050729; GO:0050830; GO:0051092; GO:0051260; GO:0051607; GO:0061702; GO:0070273; GO:0071222; GO:0071224; GO:0072559; GO:0098586; GO:0140297; GO:0140299; GO:1901223; GO:1901981; GO:2000321; GO:2000553 45692 XR_006394195.1 0 6 6 8 0 NA NA NA NA NA NA 45693 XM_029332928.1 0 0 18 0 0 P62262 8.39e-95 14-3-3 protein epsilon (14-3-3E) (Protein kinase C inhibitor protein 1) (KCIP-1) Ovis aries (Sheep) cellular response to heat [GO:0034605]; MAPK cascade [GO:0000165]; positive regulation of protein export from nucleus [GO:0046827]; protein localization to nucleus [GO:0034504] GO:0000165; GO:0005634; GO:0005737; GO:0034504; GO:0034605; GO:0042470; GO:0046827 45694 XM_044311424.1 10 9 12 15 17 Q9R1C8 7.4e-23 5-hydroxytryptamine receptor 6 (5-HT-6) (5-HT6) (Serotonin receptor 6) Mus musculus (Mouse) cerebral cortex cell migration [GO:0021795]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; learning [GO:0007612]; long-term synaptic potentiation [GO:0060291]; negative regulation of acetylcholine secretion, neurotransmission [GO:0014058]; negative regulation of gamma-aminobutyric acid secretion [GO:0014053]; negative regulation of glutamate secretion [GO:0014050]; positive regulation of dopamine secretion [GO:0033603]; positive regulation of gamma-aminobutyric acid secretion [GO:0014054]; positive regulation of TOR signaling [GO:0032008] GO:0004993; GO:0005886; GO:0005929; GO:0007187; GO:0007268; GO:0007612; GO:0014050; GO:0014053; GO:0014054; GO:0014058; GO:0021795; GO:0030425; GO:0030594; GO:0032008; GO:0033603; GO:0045202; GO:0060291 45695 XR_006391772.1 265 143 129 164 109 NA NA NA NA NA NA 45696 XR_003825459.2 10 0 13 12 24 P21328 2.56e-22 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 45697 XR_003825459.2 10 0 13 12 24 P21328 2.56e-22 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 45698 XR_006396844.1 9 0 17 3 77 NA NA NA NA NA NA 45699 XM_044328685.1 0 94 107 146 0 P16065 0 Speract receptor (EC 4.6.1.2) (Guanylate cyclase) Strongylocentrotus purpuratus (Purple sea urchin) cGMP biosynthetic process [GO:0006182]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]; receptor guanylyl cyclase signaling pathway [GO:0007168]; signal transduction [GO:0007165] GO:0001653; GO:0004383; GO:0004672; GO:0005524; GO:0005525; GO:0005886; GO:0006182; GO:0006468; GO:0007165; GO:0007168; GO:0035556 45700 XR_006398042.1 43 73 78 73 110 NA NA NA NA NA NA 45701 XR_006397103.1 0 1 0 0 10 NA NA NA NA NA NA 45702 XM_044312910.1 223 34 130 133 84 Q8R332 7.37e-62 Nucleoporin p58/p45 (58 kDa nucleoporin) (Nucleoporin-like protein 1) Mus musculus (Mouse) mRNA transport [GO:0051028]; nucleocytoplasmic transport [GO:0006913]; protein transport [GO:0015031]; regulation of protein import into nucleus [GO:0042306] GO:0005635; GO:0005643; GO:0006913; GO:0008139; GO:0015031; GO:0017056; GO:0031965; GO:0032991; GO:0042306; GO:0042802; GO:0044877; GO:0051028 45703 XM_029339949.2 1434 904 808 1248 980 Q5RID7 1.07e-130 Sorting nexin-17 Danio rerio (Zebrafish) (Brachydanio rerio) intracellular protein transport [GO:0006886]; signal transduction [GO:0007165]; vesicle-mediated transport [GO:0016192] GO:0005769; GO:0005829; GO:0006886; GO:0007165; GO:0016192; GO:0030659; GO:0031410; GO:0035091 45704 XM_029338430.2 1912 1876 1108 1294 1279 Q66L51 8.59e-118 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial (EC 2.1.1.201) (Ubiquinone biosynthesis methyltransferase COQ5) Danio rerio (Zebrafish) (Brachydanio rerio) methylation [GO:0032259]; ubiquinone biosynthetic process [GO:0006744] GO:0006744; GO:0008168; GO:0031314; GO:0032259; GO:0043333 45705 XM_029344894.2 30 22 60 190 86 NA NA NA NA NA NA 45706 XM_044320050.1 0 0 1 0 32 NA NA NA NA NA NA 45707 XR_006397392.1 381 237 147 329 354 Q54TD7 1.45e-128 ATP-dependent RNA helicase ddx24 (EC 3.6.4.13) (DEAD box protein 24) Dictyostelium discoideum (Social amoeba) NA GO:0003723; GO:0003724; GO:0005524; GO:0005730; GO:0016887 45708 XM_029328882.2 1358 1429 1179 1245 935 NA NA NA NA NA NA 45709 XM_044306884.1 12 87 5 8 8 NA NA NA NA NA NA 45710 XM_044321511.1 57 85 64 57 79 Q4R628 0 Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) centriole-centriole cohesion [GO:0010457]; cilium assembly [GO:0060271]; microtubule anchoring at centrosome [GO:0034454]; microtubule-based movement [GO:0007018] GO:0003777; GO:0005524; GO:0005737; GO:0005814; GO:0005874; GO:0005929; GO:0007018; GO:0008017; GO:0010457; GO:0034454; GO:0060271 45711 XR_006395616.1 147 56 122 121 140 NA NA NA NA NA NA 45712 XR_006398198.1 21049 24669 21061 52374 31323 NA NA NA NA NA NA 45713 XM_029335035.2 53 47 0 0 2 O94766 8.49e-81 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 (EC 2.4.1.135) (Beta-1,3-glucuronyltransferase 3) (Glucuronosyltransferase I) (GlcAT-I) (UDP-GlcUA:Gal beta-1,3-Gal-R glucuronyltransferase) (GlcUAT-I) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; chondroitin sulfate proteoglycan biosynthetic process [GO:0050650]; dermatan sulfate proteoglycan biosynthetic process [GO:0050651]; glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; positive regulation of catalytic activity [GO:0043085]; positive regulation of intracellular protein transport [GO:0090316]; protein glycosylation [GO:0006486] GO:0000139; GO:0005794; GO:0005801; GO:0005975; GO:0006024; GO:0006486; GO:0015012; GO:0015018; GO:0015020; GO:0016020; GO:0043085; GO:0046872; GO:0050650; GO:0050651; GO:0070062; GO:0072542; GO:0090316 45714 XM_029334190.2 119 0 237 40 59 Q149M9 2.7e-150 NACHT domain- and WD repeat-containing protein 1 Homo sapiens (Human) negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of gene expression [GO:0010628] GO:0005524; GO:0005730; GO:0005829; GO:0010628; GO:0032088 45715 XM_044312503.1 0 0 38 2 157 P84239 9.89e-90 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 45716 XR_006391679.1 306 148 146 178 132 NA NA NA NA NA NA 45717 XM_029353569.2 938 942 564 753 578 Q9NRZ9 0 Lymphoid-specific helicase (EC 3.6.4.-) (Proliferation-associated SNF2-like protein) (SWI/SNF2-related matrix-associated actin-dependent regulator of chromatin subfamily A member 6) Homo sapiens (Human) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to leukemia inhibitory factor [GO:1990830]; DNA methylation [GO:0006306]; DNA methylation-dependent heterochromatin formation [GO:0006346]; kidney development [GO:0001822]; lymphocyte proliferation [GO:0046651]; maintenance of DNA methylation [GO:0010216]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; pericentric heterochromatin formation [GO:0031508]; urogenital system development [GO:0001655] GO:0000775; GO:0001655; GO:0001822; GO:0003682; GO:0004386; GO:0005524; GO:0005634; GO:0005721; GO:0006306; GO:0006346; GO:0006915; GO:0007049; GO:0010216; GO:0016787; GO:0031508; GO:0046651; GO:0051301; GO:0140658; GO:1990830; GO:2001243 45718 XM_044314907.1 6778 5720 4533 7405 4321 A2AAY5 7.94e-52 SH3 and PX domain-containing protein 2B (Factor for adipocyte differentiation 49) (Tyrosine kinase substrate with four SH3 domains) Mus musculus (Mouse) adipose tissue development [GO:0060612]; bone development [GO:0060348]; cranial skeletal system development [GO:1904888]; extracellular matrix disassembly [GO:0022617]; eye development [GO:0001654]; heart development [GO:0007507]; osteoblast fate commitment [GO:0002051]; podosome assembly [GO:0071800]; positive regulation of adipose tissue development [GO:1904179]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of gene expression [GO:0010628]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of stress fiber assembly [GO:0051496]; protein localization to membrane [GO:0072657]; regulation of brood size [GO:0060378]; skeletal system development [GO:0001501]; skeletal system morphogenesis [GO:0048705]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801] GO:0001501; GO:0001654; GO:0002051; GO:0002102; GO:0005737; GO:0006801; GO:0007507; GO:0010314; GO:0010628; GO:0016176; GO:0022617; GO:0032266; GO:0040018; GO:0042169; GO:0042554; GO:0042995; GO:0045600; GO:0048705; GO:0051496; GO:0060348; GO:0060378; GO:0060612; GO:0070161; GO:0070273; GO:0071800; GO:0072657; GO:0080025; GO:1904179; GO:1904888 45719 XM_029338098.2 42 71 29 81 32 NA NA NA NA NA NA 45720 XM_029355787.2 442 469 440 1004 625 NA NA NA NA NA NA 45721 XM_044308818.1 17 6 18 2 30 NA NA NA NA NA NA 45722 XR_006392106.1 102 48 11 102 68 NA NA NA NA NA NA 45723 XM_029346342.2 0 12 0 0 0 Q07263 2.67e-85 Neuronal acetylcholine receptor subunit alpha-3 Bos taurus (Bovine) behavioral response to nicotine [GO:0035095]; chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; nervous system development [GO:0007399]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165]; synaptic transmission involved in micturition [GO:0060084] GO:0005231; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0007399; GO:0015464; GO:0022848; GO:0030594; GO:0034220; GO:0035095; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0060084; GO:1904315 45724 XM_029353344.2 507 371 277 389 427 P49256 4.99e-91 Vesicular integral-membrane protein VIP36 (Lectin mannose-binding 2) (Vesicular integral-membrane protein 36) (VIP36) Canis lupus familiaris (Dog) (Canis familiaris) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of phagocytosis [GO:0050766]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] GO:0000139; GO:0005537; GO:0005615; GO:0005789; GO:0005793; GO:0005794; GO:0005886; GO:0006888; GO:0006890; GO:0009986; GO:0015031; GO:0030134; GO:0030137; GO:0031072; GO:0031410; GO:0046872; GO:0048471; GO:0050766; GO:0070382 45725 XM_029324829.2 0 0 0 6 8 NA NA NA NA NA NA 45726 XM_044313937.1 104 167 7 17 15 NA NA NA NA NA NA 45727 XM_044318789.1 511 263 309 373 131 NA NA NA NA NA NA 45728 XM_044307629.1 0 203 253 243 212 NA NA NA NA NA NA 45729 XM_029339552.2 12 9 0 0 22 NA NA NA NA NA NA 45730 XR_006396207.1 199 101 88 79 61 Q99570 8.86e-58 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 45731 XR_006396207.1 199 101 88 79 61 Q99570 8.86e-58 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 45732 XR_006396207.1 199 101 88 79 61 Q99570 8.86e-58 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 45733 XR_003823043.2 103 0 40 144 78 NA NA NA NA NA NA 45734 XM_029335431.2 2449 2148 1596 2868 1800 NA NA NA NA NA NA 45735 XM_029347247.2 1486 428 1181 434 1185 P13255 4.53e-108 Glycine N-methyltransferase (EC 2.1.1.20) (Folate-binding protein) Rattus norvegicus (Rat) folic acid metabolic process [GO:0046655]; glycine metabolic process [GO:0006544]; glycogen metabolic process [GO:0005977]; methionine metabolic process [GO:0006555]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein homotetramerization [GO:0051289]; regulation of gluconeogenesis [GO:0006111]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; sarcosine metabolic process [GO:1901052] GO:0005542; GO:0005634; GO:0005829; GO:0005977; GO:0006111; GO:0006544; GO:0006555; GO:0006730; GO:0008757; GO:0016594; GO:0017174; GO:0032259; GO:0034708; GO:0042802; GO:0046498; GO:0046500; GO:0046655; GO:0051289; GO:0098603; GO:1901052; GO:1904047 45736 XM_044315942.1 2 5 38 19 72 NA NA NA NA NA NA 45737 XM_029341852.2 3705 3494 2968 3756 3501 NA NA NA NA NA NA 45738 XM_029333496.2 0 1 0 21 8 NA NA NA NA NA NA 45739 XR_003825856.2 251 274 307 253 381 NA NA NA NA NA NA 45740 XM_029356252.2 2090 3283 2073 1937 1370 NA NA NA NA NA NA 45741 XM_029347453.2 0 1 25 201 222 Q13416 2.59e-112 Origin recognition complex subunit 2 Homo sapiens (Human) DNA replication initiation [GO:0006270]; negative regulation of transcription by RNA polymerase II [GO:0000122] GO:0000122; GO:0000781; GO:0000792; GO:0000808; GO:0000939; GO:0003688; GO:0005634; GO:0005654; GO:0005664; GO:0005813; GO:0006270; GO:0016020 45742 XM_029334557.2 175 573 741 744 1271 P46250 5.3e-32 SEC14 cytosolic factor (Phosphatidylinositol/phosphatidylcholine transfer protein) (PI/PC TP) Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) ascospore formation [GO:0030437]; CDP-choline pathway [GO:0006657]; Golgi to plasma membrane protein transport [GO:0043001]; Golgi to vacuole transport [GO:0006896]; Golgi vesicle budding [GO:0048194]; negative regulation of phosphatidylcholine biosynthetic process [GO:2001246]; negative regulation of phosphatidylglycerol biosynthetic process [GO:1901352]; phosphatidylinositol metabolic process [GO:0046488]; post-Golgi vesicle-mediated transport [GO:0006892] GO:0000139; GO:0005794; GO:0005829; GO:0006657; GO:0006892; GO:0006896; GO:0008525; GO:0008526; GO:0030437; GO:0043001; GO:0046488; GO:0048194; GO:1901352; GO:2001246 45743 XM_044323028.1 884 575 461 875 632 Q80UG8 0 Tubulin monoglutamylase TTLL4 (EC 6.3.2.-) (Protein monoglutamylase TTLL4) (Tubulin--tyrosine ligase-like protein 4) Mus musculus (Mouse) microtubule cytoskeleton organization [GO:0000226]; peptidyl-glutamic acid modification [GO:0018200]; protein polyglutamylation [GO:0018095]; regulation of blastocyst development [GO:0120222] GO:0000226; GO:0005524; GO:0005737; GO:0005874; GO:0005929; GO:0015631; GO:0018095; GO:0018200; GO:0036064; GO:0046872; GO:0070739; GO:0070740; GO:0097731; GO:0120222 45744 XM_044326571.1 957 687 1345 1960 18 NA NA NA NA NA NA 45745 XM_029341935.2 551 484 164 569 621 P25490 2.92e-94 Transcriptional repressor protein YY1 (Delta transcription factor) (INO80 complex subunit S) (NF-E1) (Yin and yang 1) (YY-1) Homo sapiens (Human) anterior/posterior pattern specification [GO:0009952]; B cell differentiation [GO:0030183]; camera-type eye morphogenesis [GO:0048593]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to interleukin-1 [GO:0071347]; cellular response to UV [GO:0034644]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; negative regulation of cell growth involved in cardiac muscle cell development [GO:0061052]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of miRNA transcription [GO:1902894]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of telomere maintenance in response to DNA damage [GO:1904507]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell cycle [GO:0051726]; regulation of chromosome organization [GO:0033044]; regulation of DNA repair [GO:0006282]; regulation of DNA replication [GO:0006275]; regulation of DNA strand elongation [GO:0060382]; regulation of embryonic development [GO:0045995]; regulation of transcription by RNA polymerase II [GO:0006357]; response to prostaglandin F [GO:0034696]; response to UV-C [GO:0010225]; RNA localization [GO:0006403]; spermatogenesis [GO:0007283]; telomere maintenance [GO:0000723] GO:0000122; GO:0000400; GO:0000723; GO:0000724; GO:0000976; GO:0000978; GO:0000981; GO:0000987; GO:0001217; GO:0001227; GO:0001228; GO:0003677; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005667; GO:0005677; GO:0005737; GO:0006275; GO:0006282; GO:0006338; GO:0006357; GO:0006403; GO:0006974; GO:0007283; GO:0009952; GO:0010225; GO:0010628; GO:0010629; GO:0016363; GO:0030183; GO:0031011; GO:0031519; GO:0032688; GO:0033044; GO:0034644; GO:0034696; GO:0045739; GO:0045893; GO:0045944; GO:0045995; GO:0046332; GO:0046872; GO:0048593; GO:0051726; GO:0060382; GO:0061052; GO:0071347; GO:0071707; GO:0140297; GO:1902894; GO:1904507; GO:1990837 45746 XM_029333216.2 49 18 4 28 41 A0A1L8GWK2 1.5e-155 NA NA NA NA 45747 XM_029341058.2 7 0 7 0 30 NA NA NA NA NA NA 45748 XM_044312213.1 187 89 131 60 82 NA NA NA NA NA NA 45749 XM_044326046.1 384 247 240 375 183 NA NA NA NA NA NA 45750 XM_044322911.1 22 0 50 38 0 Q8N2E2 4.08e-40 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 45751 XM_044322911.1 22 0 50 38 0 Q8N2E2 1.95e-38 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 45752 XM_044322911.1 22 0 50 38 0 Q8N2E2 3.5e-37 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 45753 XM_044322911.1 22 0 50 38 0 Q8N2E2 1.77e-35 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 45754 XM_044322911.1 22 0 50 38 0 Q8N2E2 1.53e-32 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 45755 XM_044322911.1 22 0 50 38 0 Q8N2E2 1.74e-25 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 45756 XM_029334203.2 87 45 24 30 54 Q9IB89 2.07e-89 Zinc finger protein ZIC 5 (XZic5) (XlZic5) (Zinc finger protein of the cerebellum 5) Xenopus laevis (African clawed frog) nervous system development [GO:0007399]; neural crest formation [GO:0014029] GO:0003677; GO:0005634; GO:0007399; GO:0014029; GO:0046872 45757 XM_044322800.1 598 0 14 0 0 Q13591 1.84e-71 Semaphorin-5A (Semaphorin-F) (Sema F) Homo sapiens (Human) axon extension [GO:0048675]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell-cell signaling [GO:0007267]; diencephalon development [GO:0021536]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of cell adhesion [GO:0007162]; negative regulation of endothelial cell apoptotic process [GO:2000352]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; positive chemotaxis [GO:0050918]; positive regulation of actin filament depolymerization [GO:0030836]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein kinase B signaling [GO:0051897]; semaphorin-plexin signaling pathway [GO:0071526]; signal clustering [GO:1990256] GO:0001755; GO:0001938; GO:0002043; GO:0005886; GO:0007155; GO:0007162; GO:0007267; GO:0007399; GO:0007411; GO:0007413; GO:0016020; GO:0021536; GO:0030215; GO:0030335; GO:0030836; GO:0035373; GO:0043395; GO:0045499; GO:0045545; GO:0045766; GO:0048675; GO:0048842; GO:0048843; GO:0050918; GO:0051897; GO:0060326; GO:0070062; GO:0071526; GO:0090263; GO:1990256; GO:2000352; GO:2001028 45758 XM_044315220.1 48 68 44 71 83 NA NA NA NA NA NA 45759 XM_044313623.1 18 20 7 54 35 NA NA NA NA NA NA 45760 XM_044323372.1 8 0 10 0 8 NA NA NA NA NA NA 45761 XR_006397876.1 22 6 0 2 133 NA NA NA NA NA NA 45762 XM_029355353.2 340 439 197 683 506 Q8N2I9 1.18e-157 Serine/threonine-protein kinase 40 (EC 2.7.11.1) (SINK-homologous serine/threonine-protein kinase) (Sugen kinase 495) (SgK495) Homo sapiens (Human) glycogen metabolic process [GO:0005977]; lung alveolus development [GO:0048286]; lung morphogenesis [GO:0060425]; multicellular organism growth [GO:0035264]; negative regulation of apoptotic process [GO:0043066]; protein phosphorylation [GO:0006468]; regulation of gene expression [GO:0010468]; regulation of MAPK cascade [GO:0043408]; respiratory system process [GO:0003016] GO:0003016; GO:0004674; GO:0005524; GO:0005654; GO:0005829; GO:0005977; GO:0006468; GO:0010468; GO:0035264; GO:0043066; GO:0043408; GO:0048286; GO:0060425; GO:0106310 45763 XM_044307841.1 6 65 0 13 10 Q2KIL7 1.6e-26 R3H domain-containing protein 4 Bos taurus (Bovine) NA GO:0003676; GO:0005634 45764 XM_044318253.1 125 31 84 39 134 NA NA NA NA NA NA 45765 XM_029350880.2 693 521 446 923 803 Q6NTV6 1.58e-73 Inverted formin-2 Xenopus laevis (African clawed frog) actin cytoskeleton organization [GO:0030036] GO:0003779; GO:0030036; GO:0031267 45766 XM_029350880.2 693 521 446 923 803 Q6NTV6 1.67e-60 Inverted formin-2 Xenopus laevis (African clawed frog) actin cytoskeleton organization [GO:0030036] GO:0003779; GO:0030036; GO:0031267 45767 XM_044320834.1 11 0 2 72 71 NA NA NA NA NA NA 45768 XM_029327060.2 654 368 293 427 396 Q5ZK21 3.37e-136 Integrator complex subunit 14 (von Willebrand factor A domain-containing protein 9) Gallus gallus (Chicken) snRNA 3'-end processing [GO:0034472] GO:0032039; GO:0034472 45769 XM_044325595.1 0 0 0 0 25 NA NA NA NA NA NA 45770 XM_044319830.1 1735 1887 1629 2161 2392 Q96RW7 7.32e-67 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 45771 XM_044319830.1 1735 1887 1629 2161 2392 Q96RW7 1.66e-59 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 45772 XM_044319830.1 1735 1887 1629 2161 2392 Q96RW7 1.29e-57 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 45773 XM_044319830.1 1735 1887 1629 2161 2392 Q96RW7 1.67e-54 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 45774 XM_044319830.1 1735 1887 1629 2161 2392 Q96RW7 7.6e-54 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 45775 XM_044319830.1 1735 1887 1629 2161 2392 Q96RW7 1.24e-53 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 45776 XM_044319830.1 1735 1887 1629 2161 2392 Q96RW7 1.48e-52 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 45777 XM_044319830.1 1735 1887 1629 2161 2392 Q96RW7 2.63e-51 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 45778 XM_044319830.1 1735 1887 1629 2161 2392 Q96RW7 1.78e-50 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 45779 XM_044319830.1 1735 1887 1629 2161 2392 Q96RW7 5.55e-50 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 45780 XM_044319830.1 1735 1887 1629 2161 2392 Q96RW7 9.03e-50 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 45781 XM_044319830.1 1735 1887 1629 2161 2392 Q96RW7 1.04e-47 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 45782 XM_044319830.1 1735 1887 1629 2161 2392 Q96RW7 2.85e-47 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 45783 XM_044319830.1 1735 1887 1629 2161 2392 Q96RW7 1.46e-45 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 45784 XM_044319830.1 1735 1887 1629 2161 2392 Q96RW7 2.05e-39 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 45785 XM_044319830.1 1735 1887 1629 2161 2392 Q96RW7 2.95e-39 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 45786 XM_044319830.1 1735 1887 1629 2161 2392 Q96RW7 2.14e-24 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 45787 XM_029351591.2 210 129 165 287 237 O15439 0 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 45788 XM_029356285.2 1214 1068 731 998 1197 Q9D0F3 1.47e-114 Protein ERGIC-53 (ER-Golgi intermediate compartment 53 kDa protein) (Lectin mannose-binding 1) (p58) Mus musculus (Mouse) endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; positive regulation of organelle organization [GO:0010638]; protein transport [GO:0015031]; sequestering of metal ion [GO:0051238] GO:0000139; GO:0005537; GO:0005783; GO:0005789; GO:0005793; GO:0005794; GO:0006888; GO:0007029; GO:0007030; GO:0010638; GO:0015031; GO:0016020; GO:0030017; GO:0030134; GO:0033116; GO:0042802; GO:0043231; GO:0046872; GO:0051238; GO:0062023 45789 XM_044324475.1 50 0 114 137 0 NA NA NA NA NA NA 45790 XM_044317887.1 0 2 0 109 56 Q9CWQ2 2.45e-30 Zinc finger SWIM domain-containing protein 7 (SWIM domain-containing and Srs2-interacting protein 1 homolog) Mus musculus (Mouse) double-strand break repair via homologous recombination [GO:0000724]; protein stabilization [GO:0050821] GO:0000724; GO:0005634; GO:0008270; GO:0050821; GO:0097196 45791 XM_044319880.1 55 0 0 0 0 Q54PH5 9.21e-65 Pre-mRNA-splicing factor cwc2 Dictyostelium discoideum (Social amoeba) mRNA cis splicing, via spliceosome [GO:0045292]; positive regulation of cell cycle [GO:0045787]; positive regulation of RNA splicing [GO:0033120]; spliceosomal snRNP assembly [GO:0000387] GO:0000387; GO:0000974; GO:0005634; GO:0005681; GO:0017070; GO:0033120; GO:0036002; GO:0045292; GO:0045787; GO:0046872; GO:0071006; GO:0071007 45792 XM_044324669.1 644 0 0 415 226 Q01484 1.08e-22 Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin) Homo sapiens (Human) atrial cardiac muscle cell action potential [GO:0086014]; atrial cardiac muscle cell to AV node cell communication [GO:0086066]; atrial septum development [GO:0003283]; cellular calcium ion homeostasis [GO:0006874]; endocytosis [GO:0006897]; membrane depolarization during SA node cell action potential [GO:0086046]; paranodal junction assembly [GO:0030913]; positive regulation of calcium ion transmembrane transporter activity [GO:1901021]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cation channel activity [GO:2001259]; positive regulation of gene expression [GO:0010628]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to endoplasmic reticulum [GO:0070972]; protein localization to M-band [GO:0036309]; protein localization to organelle [GO:0033365]; protein localization to plasma membrane [GO:0072659]; protein localization to T-tubule [GO:0036371]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; regulation of atrial cardiac muscle cell action potential [GO:0098910]; regulation of calcium ion transmembrane transporter activity [GO:1901019]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of heart rate [GO:0002027]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of protein stability [GO:0031647]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of SA node cell action potential [GO:0098907]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; response to methylmercury [GO:0051597]; SA node cell action potential [GO:0086015]; SA node cell to atrial cardiac muscle cell communication [GO:0086070]; sarcoplasmic reticulum calcium ion transport [GO:0070296]; T-tubule organization [GO:0033292]; ventricular cardiac muscle cell action potential [GO:0086005] GO:0002027; GO:0003283; GO:0005200; GO:0005739; GO:0005764; GO:0005769; GO:0005829; GO:0005856; GO:0005886; GO:0006874; GO:0006897; GO:0008093; GO:0008104; GO:0010628; GO:0010881; GO:0010882; GO:0014704; GO:0015031; GO:0016323; GO:0016324; GO:0019899; GO:0019901; GO:0030018; GO:0030315; GO:0030507; GO:0030674; GO:0030913; GO:0031430; GO:0031647; GO:0031672; GO:0033292; GO:0033365; GO:0034394; GO:0036309; GO:0036371; GO:0042383; GO:0043005; GO:0043034; GO:0043268; GO:0044325; GO:0045121; GO:0045211; GO:0050821; GO:0051117; GO:0051279; GO:0051597; GO:0051924; GO:0051928; GO:0055037; GO:0055117; GO:0060307; GO:0070296; GO:0070972; GO:0072659; GO:0086004; GO:0086005; GO:0086014; GO:0086015; GO:0086046; GO:0086066; GO:0086070; GO:0086091; GO:0098907; GO:0098910; GO:0140031; GO:1901018; GO:1901019; GO:1901021; GO:2001259 45793 XM_044324669.1 644 0 0 415 226 Q01484 9.9e-21 Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin) Homo sapiens (Human) atrial cardiac muscle cell action potential [GO:0086014]; atrial cardiac muscle cell to AV node cell communication [GO:0086066]; atrial septum development [GO:0003283]; cellular calcium ion homeostasis [GO:0006874]; endocytosis [GO:0006897]; membrane depolarization during SA node cell action potential [GO:0086046]; paranodal junction assembly [GO:0030913]; positive regulation of calcium ion transmembrane transporter activity [GO:1901021]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cation channel activity [GO:2001259]; positive regulation of gene expression [GO:0010628]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to endoplasmic reticulum [GO:0070972]; protein localization to M-band [GO:0036309]; protein localization to organelle [GO:0033365]; protein localization to plasma membrane [GO:0072659]; protein localization to T-tubule [GO:0036371]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; regulation of atrial cardiac muscle cell action potential [GO:0098910]; regulation of calcium ion transmembrane transporter activity [GO:1901019]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of heart rate [GO:0002027]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of protein stability [GO:0031647]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of SA node cell action potential [GO:0098907]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; response to methylmercury [GO:0051597]; SA node cell action potential [GO:0086015]; SA node cell to atrial cardiac muscle cell communication [GO:0086070]; sarcoplasmic reticulum calcium ion transport [GO:0070296]; T-tubule organization [GO:0033292]; ventricular cardiac muscle cell action potential [GO:0086005] GO:0002027; GO:0003283; GO:0005200; GO:0005739; GO:0005764; GO:0005769; GO:0005829; GO:0005856; GO:0005886; GO:0006874; GO:0006897; GO:0008093; GO:0008104; GO:0010628; GO:0010881; GO:0010882; GO:0014704; GO:0015031; GO:0016323; GO:0016324; GO:0019899; GO:0019901; GO:0030018; GO:0030315; GO:0030507; GO:0030674; GO:0030913; GO:0031430; GO:0031647; GO:0031672; GO:0033292; GO:0033365; GO:0034394; GO:0036309; GO:0036371; GO:0042383; GO:0043005; GO:0043034; GO:0043268; GO:0044325; GO:0045121; GO:0045211; GO:0050821; GO:0051117; GO:0051279; GO:0051597; GO:0051924; GO:0051928; GO:0055037; GO:0055117; GO:0060307; GO:0070296; GO:0070972; GO:0072659; GO:0086004; GO:0086005; GO:0086014; GO:0086015; GO:0086046; GO:0086066; GO:0086070; GO:0086091; GO:0098907; GO:0098910; GO:0140031; GO:1901018; GO:1901019; GO:1901021; GO:2001259 45794 XM_029349917.2 415 335 282 343 300 NA NA NA NA NA NA 45795 XM_044311290.1 10 0 0 0 0 NA NA NA NA NA NA 45796 XM_044323136.1 0 0 0 0 11 P0CT43 7.76e-55 Transposon Tf2-8 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 45797 XM_044319840.1 55 60 38 36 129 NA NA NA NA NA NA 45798 XM_044324470.1 11 1 6 0 5 NA NA NA NA NA NA 45799 XM_044310659.1 15 6 14 3 13 NA NA NA NA NA NA 45800 XM_029346003.2 337 195 221 303 269 Q2TBP2 2.44e-127 Histone H4 transcription factor (Histone nuclear factor P) (HiNF-P) (MBD2-interacting zinc finger protein) (Methyl-CpG-binding protein 2-interacting zinc finger protein) Bos taurus (Bovine) NA GO:0003677; GO:0005634; GO:0046872 45801 XM_029323524.2 40 0 0 18 55 Q8IVF7 1.51e-63 Formin-like protein 3 (Formin homology 2 domain-containing protein 3) (WW domain-binding protein 3) (WBP-3) Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; angiogenesis [GO:0001525]; cell migration [GO:0016477]; cortical actin cytoskeleton organization [GO:0030866]; cytoskeleton organization [GO:0007010]; filopodium assembly [GO:0046847]; regulation of cell shape [GO:0008360] GO:0001525; GO:0005737; GO:0005794; GO:0005829; GO:0005886; GO:0007010; GO:0008360; GO:0016477; GO:0030866; GO:0031267; GO:0031532; GO:0032794; GO:0043231; GO:0046847; GO:0051015 45802 XM_044310094.1 10 0 21 40 6 Q3UQ28 1.49e-30 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 45803 XM_044310094.1 10 0 21 40 6 Q3UQ28 4.69e-28 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 45804 XM_044310094.1 10 0 21 40 6 Q3UQ28 3.31e-26 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 45805 XM_044310094.1 10 0 21 40 6 Q3UQ28 3.37e-23 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 45806 XM_029332990.2 0 0 22 0 0 NA NA NA NA NA NA 45807 XM_029323826.2 664 44 526 153 412 Q4G0S4 4.56e-86 Cytochrome P450 27C1 (EC 1.14.19.53) (All-trans retinol 3,4-desaturase) Homo sapiens (Human) retinal metabolic process [GO:0042574]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572] GO:0001972; GO:0004497; GO:0005502; GO:0005503; GO:0005506; GO:0005739; GO:0020037; GO:0031966; GO:0042572; GO:0042573; GO:0042574; GO:0043231; GO:0061896; GO:0061897; GO:0061898; GO:0061899; GO:1904768 45808 XM_029340824.2 9 15 1 0 7 Q2LE78 1.1e-66 BTB/POZ domain-containing protein 6 Xenopus laevis (African clawed frog) NA GO:0005737 45809 XM_029343601.2 513 242 331 525 649 NA NA NA NA NA NA 45810 XM_029324820.2 19 0 3 3 6 Q61241 4.19e-72 Testis-specific serine/threonine-protein kinase 1 (TSK-1) (TSK1) (TSSK-1) (Testis-specific kinase 1) (EC 2.7.11.1) (Serine/threonine-protein kinase 22A) Mus musculus (Mouse) intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; protein phosphorylation [GO:0006468]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283] GO:0000287; GO:0001669; GO:0004674; GO:0005524; GO:0006468; GO:0007283; GO:0007286; GO:0018105; GO:0031514; GO:0035556; GO:0044877; GO:0106310 45811 XM_044314660.1 136 32 46 188 204 NA NA NA NA NA NA 45812 XM_029343679.2 78 5 30 68 55 Q0II68 4.9e-163 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase (EC 4.1.1.45) (Picolinate carboxylase) Bos taurus (Bovine) negative regulation of quinolinate biosynthetic process [GO:1904985]; secondary metabolic process [GO:0019748] GO:0001760; GO:0005737; GO:0005829; GO:0008270; GO:0016787; GO:0016831; GO:0019748; GO:1904985 45813 XM_029324306.2 3874 4221 2889 4180 3592 Q641B9 9.85e-57 Actin-related protein 2/3 complex subunit 5-C Xenopus laevis (African clawed frog) Arp2/3 complex-mediated actin nucleation [GO:0034314]; regulation of actin filament polymerization [GO:0030833] GO:0003779; GO:0005634; GO:0005737; GO:0005885; GO:0030833; GO:0034314; GO:0035861; GO:0042995 45814 XM_044327736.1 55 190 165 245 411 R1CW23 6.32e-91 Dimethylsulfonioproprionate lyase 7 (DMSP lyase 7) (EC 4.4.1.3) (Dimethylpropiothetin dethiomethylase 7) Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi) NA GO:0047869 45815 XR_003828623.2 125 83 28 50 40 NA NA NA NA NA NA 45816 XM_029333456.2 12 1 1 5 2 A2RRH5 1.24e-143 WD repeat-containing protein 27 Homo sapiens (Human) NA GO:0005654 45817 XM_029334072.2 55 0 20 205 61 Q7TQI7 0 Ankyrin repeat and BTB/POZ domain-containing protein 2 Mus musculus (Mouse) cellular response to toxic substance [GO:0097237] GO:0046982; GO:0097237 45818 XM_044320940.1 1499 1114 1484 1567 552 Q9HDZ5 1.21e-23 CRAL-TRIO domain-containing protein C589.09, mitochondrial Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) intermembrane phospholipid transfer [GO:0120010] GO:0005739; GO:0120010; GO:0120014 45819 XM_029332052.2 4482 3387 2485 3741 3683 Q5R4U9 1.24e-80 Sorcin Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) calcium ion transport [GO:0006816]; cytoplasmic sequestering of transcription factor [GO:0042994]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of heart rate [GO:0010459]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of relaxation of muscle [GO:1901077] GO:0002020; GO:0005509; GO:0005654; GO:0005829; GO:0005886; GO:0006816; GO:0010459; GO:0030018; GO:0033017; GO:0035774; GO:0042584; GO:0042994; GO:0046982; GO:0051281; GO:0055118; GO:0060315; GO:0070062; GO:0086004; GO:0140297; GO:1901077; GO:1901841; GO:1901844; GO:2000678 45820 XR_006397027.1 0 0 0 0 8 NA NA NA NA NA NA 45821 XM_044310364.1 9 0 0 0 0 NA NA NA NA NA NA 45822 XM_029351973.2 0 23 17 0 0 NA NA NA NA NA NA 45823 XM_044309715.1 0 0 6 26 14 NA NA NA NA NA NA 45824 XM_044317030.1 188 0 0 18 0 Q32L63 5.06e-68 Vacuolar protein sorting-associated protein VTA1 homolog Bos taurus (Bovine) late endosome to vacuole transport via multivesicular body sorting pathway [GO:0032511]; protein transport [GO:0015031] GO:0010008; GO:0015031; GO:0032511 45825 XR_006391395.1 54 17 12 19 94 NA NA NA NA NA NA 45826 XM_044329213.1 0 0 0 0 11 NA NA NA NA NA NA 45827 XM_029323671.2 7 9 0 24 0 NA NA NA NA NA NA 45828 XM_029348096.2 0 11 9 11 5 O89103 5.04e-21 Complement component C1q receptor (C1q/MBL/SPA receptor) (C1qR(p)) (C1qRp) (Cell surface antigen AA4) (Complement component 1 q subcomponent receptor 1) (Lymphocyte antigen 68) (Ly-68) (CD antigen CD93) Mus musculus (Mouse) cell-cell adhesion [GO:0098609] GO:0001849; GO:0005509; GO:0005886; GO:0009986; GO:0030246; GO:0031410; GO:0098609 45829 XM_029337212.2 660 364 339 401 425 O06997 8.89e-23 Uncharacterized FAD-linked oxidoreductase YvdP (EC 1.21.-.-) (Spore coat protein YvdP) Bacillus subtilis (strain 168) sporulation resulting in formation of a cellular spore [GO:0030435] GO:0016491; GO:0030435; GO:0071949 45830 XM_044310456.1 1 0 0 3 14 NA NA NA NA NA NA 45831 XR_006392743.1 15 0 4 0 1 NA NA NA NA NA NA 45832 XR_006395798.1 249 195 182 243 159 Q8UW76 1.12e-82 T-box transcription factor TBX20 (T-box protein 20) (cTbx20) Gallus gallus (Chicken) aortic valve morphogenesis [GO:0003180]; atrial septum morphogenesis [GO:0060413]; atrioventricular canal development [GO:0036302]; blood circulation [GO:0008015]; branching involved in blood vessel morphogenesis [GO:0001569]; cardiac chamber formation [GO:0003207]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac right ventricle morphogenesis [GO:0003215]; cell fate specification [GO:0001708]; cell migration involved in heart development [GO:0060973]; cell proliferation involved in heart valve development [GO:2000793]; dorsal/ventral pattern formation [GO:0009953]; embryonic heart tube elongation [GO:0036306]; endocardial cushion formation [GO:0003272]; foramen ovale closure [GO:0035922]; heart looping [GO:0001947]; mesenchymal cell development [GO:0014031]; motor neuron migration [GO:0097475]; muscle contraction [GO:0006936]; negative regulation of gene expression [GO:0010629]; negative regulation of SMAD protein complex assembly [GO:0010991]; negative regulation of transcription by RNA polymerase II [GO:0000122]; outflow tract septum morphogenesis [GO:0003148]; pericardium morphogenesis [GO:0003344]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell migration [GO:0030335]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of gene expression [GO:0010628]; pulmonary valve formation [GO:0003193]; pulmonary vein morphogenesis [GO:0060577]; regulation of transcription by RNA polymerase II [GO:0006357]; tricuspid valve development [GO:0003175]; vasculogenesis [GO:0001570]; visceral motor neuron differentiation [GO:0021524] GO:0000122; GO:0000978; GO:0000981; GO:0001228; GO:0001569; GO:0001570; GO:0001708; GO:0001947; GO:0003148; GO:0003175; GO:0003180; GO:0003193; GO:0003207; GO:0003215; GO:0003272; GO:0003344; GO:0005634; GO:0005737; GO:0006357; GO:0006936; GO:0008015; GO:0009953; GO:0010628; GO:0010629; GO:0010718; GO:0010991; GO:0014031; GO:0021524; GO:0030335; GO:0030513; GO:0035922; GO:0036302; GO:0036306; GO:0055008; GO:0060045; GO:0060413; GO:0060577; GO:0060973; GO:0061629; GO:0097475; GO:2000793 45833 XM_044324104.1 5 0 1 3 15 NA NA NA NA NA NA 45834 XM_044325357.1 0 0 7 0 31 P48733 3.55e-30 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Bos taurus (Bovine) antibacterial innate immune response [GO:0140367]; defense response to Gram-negative bacterium [GO:0050829] GO:0000922; GO:0005201; GO:0005509; GO:0005576; GO:0005929; GO:0016020; GO:0016323; GO:0016324; GO:0031012; GO:0050829; GO:0060170; GO:0140367 45835 XM_044324541.1 0 0 0 0 52 NA NA NA NA NA NA 45836 XM_044308301.1 402 248 185 301 434 NA NA NA NA NA NA 45837 XM_044313628.1 0 53 0 0 56 NA NA NA NA NA NA 45838 XR_006397230.1 104 204 16 44 81 NA NA NA NA NA NA 45839 XM_044319774.1 3126 3188 1613 1675 1865 E2RDZ6 4.27e-116 NAD-dependent protein deacylase sirtuin-5, mitochondrial (EC 2.3.1.-) (Regulatory protein SIR2 homolog 5) (SIR2-like protein 5) Canis lupus familiaris (Dog) (Canis familiaris) peptidyl-lysine demalonylation [GO:0036047]; peptidyl-lysine desuccinylation [GO:0036049]; protein deacetylation [GO:0006476]; protein deglutarylation [GO:0061698]; protein demalonylation [GO:0036046]; protein desuccinylation [GO:0036048]; regulation of ketone biosynthetic process [GO:0010566] GO:0005634; GO:0005739; GO:0005829; GO:0006476; GO:0008270; GO:0010566; GO:0016740; GO:0034979; GO:0036046; GO:0036047; GO:0036048; GO:0036049; GO:0036054; GO:0036055; GO:0061697; GO:0061698; GO:0070403 45840 XR_006396380.1 32 0 0 36 0 NA NA NA NA NA NA 45841 XM_044312713.1 84 52 89 159 78 NA NA NA NA NA NA 45842 XR_003825803.2 110 106 35 132 116 NA NA NA NA NA NA 45843 XM_029351351.2 138 112 108 209 262 Q6NS23 7.98e-137 tRNA (guanine(10)-N2)-methyltransferase homolog (EC 2.1.1.-) (tRNA guanosine-2'-O-methyltransferase TRM11 homolog) Xenopus laevis (African clawed frog) RNA methylation [GO:0001510]; tRNA processing [GO:0008033] GO:0000049; GO:0001510; GO:0008033; GO:0008168 45844 XR_003827663.2 11 13 63 6 40 NA NA NA NA NA NA 45845 XM_044328411.1 4403 3905 1973 4945 3836 F1R8Z9 3.15e-52 Forkhead box protein J1-B Danio rerio (Zebrafish) (Brachydanio rerio) auditory receptor cell stereocilium organization [GO:0060088]; cilium assembly [GO:0060271]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; heart looping [GO:0001947]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0001947; GO:0003146; GO:0005634; GO:0006357; GO:0007368; GO:0060088; GO:0060271 45846 XM_044310458.1 907 19 28 514 200 Q8R151 0 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 45847 XM_044329148.1 1429 1078 659 1522 1168 P23098 0 Dynein beta chain, ciliary Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla) cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] GO:0005524; GO:0005737; GO:0005874; GO:0007018; GO:0008569; GO:0030030; GO:0030286; GO:0045505; GO:0051959; GO:0097729 45848 XM_029351039.2 297 464 247 407 448 NA NA NA NA NA NA 45849 XM_044328071.1 0 0 0 25 664 NA NA NA NA NA NA 45850 XR_006394127.1 50 24 23 5 6 NA NA NA NA NA NA 45851 XM_044317484.1 0 0 0 520 0 Q13114 2.64e-99 TNF receptor-associated factor 3 (EC 2.3.2.27) (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein 1) (LAP1) (RING-type E3 ubiquitin transferase TRAF3) Homo sapiens (Human) apoptotic process [GO:0006915]; defense response to virus [GO:0051607]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of JNK cascade [GO:0046330]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of cytokine production [GO:0001817]; regulation of defense response to virus [GO:0050688]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of interferon-beta production [GO:0032648]; regulation of proteolysis [GO:0030162]; signal transduction [GO:0007165]; Toll signaling pathway [GO:0008063]; toll-like receptor signaling pathway [GO:0002224]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; type I interferon-mediated signaling pathway [GO:0060337] GO:0000151; GO:0001817; GO:0002224; GO:0004842; GO:0005164; GO:0005739; GO:0005768; GO:0005829; GO:0006915; GO:0007165; GO:0008063; GO:0008270; GO:0009898; GO:0019901; GO:0019903; GO:0030162; GO:0031625; GO:0031996; GO:0032088; GO:0032648; GO:0033209; GO:0035631; GO:0035666; GO:0042802; GO:0042981; GO:0043122; GO:0046330; GO:0050688; GO:0051607; GO:0060337; GO:0070534; GO:1902554 45852 XM_044317542.1 4863 13506 2439 4358 4038 Q9H4G4 7.48e-39 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Homo sapiens (Human) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070062; GO:0070374 45853 XM_044317542.1 4863 13506 2439 4358 4038 Q9H4G4 7.85e-39 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Homo sapiens (Human) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070062; GO:0070374 45854 XM_044317542.1 4863 13506 2439 4358 4038 Q9H4G4 3.87e-34 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Homo sapiens (Human) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070062; GO:0070374 45855 XM_044317542.1 4863 13506 2439 4358 4038 Q9H4G4 2.75e-31 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Homo sapiens (Human) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070062; GO:0070374 45856 XM_029331133.2 0 7 0 6 0 Q9C0A0 9.11e-29 Contactin-associated protein-like 4 (Cell recognition molecule Caspr4) Homo sapiens (Human) cell adhesion [GO:0007155]; regulation of grooming behavior [GO:2000821]; regulation of synaptic transmission, dopaminergic [GO:0032225]; regulation of synaptic transmission, GABAergic [GO:0032228] GO:0007155; GO:0032225; GO:0032228; GO:0042734; GO:0042995; GO:2000821 45857 XM_029330781.2 2281 2362 1601 2195 1897 P53356 4.12e-130 Tyrosine-protein kinase HTK16 (EC 2.7.10.2) Hydra vulgaris (Hydra) (Hydra attenuata) NA GO:0004715; GO:0005524 45858 XM_029330781.2 2281 2362 1601 2195 1897 P53356 4.27e-115 Tyrosine-protein kinase HTK16 (EC 2.7.10.2) Hydra vulgaris (Hydra) (Hydra attenuata) NA GO:0004715; GO:0005524 45859 XM_029325330.2 1395 991 657 1255 994 Q7TN22 8.05e-39 Thioredoxin domain-containing protein 16 Mus musculus (Mouse) NA GO:0005576; GO:0005788 45860 XM_044310453.1 176 17 0 37 38 NA NA NA NA NA NA 45861 XR_003826222.2 0 22 0 33 5 NA NA NA NA NA NA 45862 XM_029326789.2 1 11 0 3 2 Q9NPC3 4.65e-70 E3 ubiquitin-protein ligase CCNB1IP1 (EC 2.3.2.27) (Cyclin-B1-interacting protein 1) (Human enhancer of invasion 10) (RING-type E3 ubiquitin transferase CCNB1IP1) Homo sapiens (Human) blastocyst formation [GO:0001825]; chiasma assembly [GO:0051026]; reciprocal meiotic recombination [GO:0007131]; spermatid development [GO:0007286] GO:0000795; GO:0001825; GO:0007131; GO:0007286; GO:0042802; GO:0046872; GO:0051026; GO:0061630 45863 XM_044320711.1 0 1 0 0 9 NA NA NA NA NA NA 45864 XM_029346408.2 26 13 54 46 29 Q9H4I8 2.9e-48 Serine hydrolase-like protein 2 (EC 3.1.-.-) Homo sapiens (Human) NA GO:0005777; GO:0016787; GO:0048471 45865 XR_003827512.2 117 96 107 83 97 NA NA NA NA NA NA 45866 XM_029343281.2 0 0 38 15 0 Q0VEJ0 0 Centrosomal protein of 76 kDa (Cep76) Mus musculus (Mouse) regulation of centriole replication [GO:0046599] GO:0005737; GO:0005813; GO:0005814; GO:0032991; GO:0046599 45867 XM_044311432.1 2 13 0 0 0 NA NA NA NA NA NA 45868 XM_044327868.1 21 0 0 1 21 Q09575 1.19e-42 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 45869 XM_044307036.1 2344 3608 1848 1521 1507 NA NA NA NA NA NA 45870 XM_029331600.2 438 234 238 1056 819 NA NA NA NA NA NA 45871 XM_044306829.1 449 693 1 234 94 Q3B8R1 1.27e-79 Endoplasmic reticulum membrane-associated RNA degradation protein (ER membrane-associated RNA degradation protein) Rattus norvegicus (Rat) NA GO:0005789 45872 XM_044321691.1 15304 7022 5544 17392 7859 NA NA NA NA NA NA 45873 XM_044317996.1 1408 1020 1102 970 1062 Q26619 1.31e-110 cAMP-dependent protein kinase type II regulatory subunit Strongylocentrotus purpuratus (Purple sea urchin) negative regulation of cAMP-dependent protein kinase activity [GO:2000480] GO:0004862; GO:0005737; GO:0005952; GO:0030552; GO:0034236; GO:2000480 45874 XM_044307308.1 4663 2662 2434 4497 3470 Q9QWW1 1.32e-78 Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up-regulated during seizure and LTP 2) (Vesl-2) Mus musculus (Mouse) behavioral response to cocaine [GO:0048148]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; G protein-coupled glutamate receptor signaling pathway [GO:0007216]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of interleukin-2 production [GO:0032703]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; regulation of store-operated calcium entry [GO:2001256]; sensory perception of sound [GO:0007605] GO:0003779; GO:0005737; GO:0005829; GO:0005886; GO:0007216; GO:0007605; GO:0008277; GO:0014069; GO:0019904; GO:0030160; GO:0030425; GO:0032426; GO:0032703; GO:0035254; GO:0035256; GO:0035584; GO:0042802; GO:0043025; GO:0043229; GO:0044877; GO:0045177; GO:0048148; GO:0070885; GO:0098978; GO:2001256 45875 XM_029347651.2 56 16 3 2 117 NA NA NA NA NA NA 45876 XR_006391562.1 0 16 16 10 4 NA NA NA NA NA NA 45877 XM_044325045.1 0 185 1 0 157 NA NA NA NA NA NA 45878 XM_029357206.2 241 80 64 137 213 P54315 2.19e-65 Inactive pancreatic lipase-related protein 1 (PL-RP1) Homo sapiens (Human) lipid metabolic process [GO:0006629] GO:0004806; GO:0005509; GO:0005576; GO:0006629 45879 XM_044314234.1 23 6 7 6 2 P34457 5.97e-27 Putative uncharacterized transposon-derived protein F54H12.3 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0015074 45880 XM_029327489.2 513 216 395 481 528 O43826 1.12e-84 Glucose-6-phosphate exchanger SLC37A4 (Glucose-5-phosphate transporter) (Glucose-6-phosphate translocase) (Solute carrier family 37 member 4) (Transformation-related gene 19 protein) (TRG-19) Homo sapiens (Human) carbohydrate transport [GO:0008643]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; glucose-6-phosphate transport [GO:0015760]; phosphate ion transmembrane transport [GO:0035435] GO:0005783; GO:0005789; GO:0006006; GO:0006094; GO:0008643; GO:0015152; GO:0015760; GO:0016020; GO:0035435; GO:0042593; GO:0061513 45881 XM_029327184.2 0 0 0 0 31 Q96DM1 3.58e-55 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 45882 XM_029327184.2 0 0 0 0 31 Q96DM1 3.58e-55 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 45883 XM_044312559.1 55 700 175 64 207 NA NA NA NA NA NA 45884 XM_044326037.1 541 523 764 304 263 NA NA NA NA NA NA 45885 XM_044322625.1 0 0 0 0 184 NA NA NA NA NA NA 45886 XM_044319160.1 16 60 8 17 22 NA NA NA NA NA NA 45887 XM_044311789.1 10 14 121 35 10 NA NA NA NA NA NA 45888 XM_029340713.2 585 232 375 258 675 Q9NQX0 2.49e-49 Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.361) (PR domain zinc finger protein 6) (PR domain-containing protein 6) Homo sapiens (Human) chromatin organization [GO:0006325]; histone methylation [GO:0016571]; negative regulation of smooth muscle cell differentiation [GO:0051151]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of gene expression [GO:0010468] GO:0000122; GO:0005634; GO:0006325; GO:0010468; GO:0016571; GO:0022008; GO:0042802; GO:0046872; GO:0051151; GO:0140944 45889 XM_029340713.2 585 232 375 258 675 Q9NQX0 3.77e-31 Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.361) (PR domain zinc finger protein 6) (PR domain-containing protein 6) Homo sapiens (Human) chromatin organization [GO:0006325]; histone methylation [GO:0016571]; negative regulation of smooth muscle cell differentiation [GO:0051151]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of gene expression [GO:0010468] GO:0000122; GO:0005634; GO:0006325; GO:0010468; GO:0016571; GO:0022008; GO:0042802; GO:0046872; GO:0051151; GO:0140944 45890 XM_029346498.2 3603 6136 3789 3107 1759 Q6DHQ1 2.15e-29 Voltage-gated hydrogen channel 1 (Hydrogen voltage-gated channel 1) (HV1) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to pH [GO:0071467]; cellular response to zinc ion [GO:0071294]; proton transmembrane transport [GO:1902600]; regulation of ion transmembrane transport [GO:0034765]; response to zinc ion [GO:0010043] GO:0005886; GO:0008270; GO:0010043; GO:0030171; GO:0034765; GO:0071294; GO:0071467; GO:1902600 45891 XM_029342000.2 442 0 0 35 0 Q9VE46 0 High-affinity choline transporter 1 Drosophila melanogaster (Fruit fly) acetylcholine biosynthetic process [GO:0008292]; amino acid transmembrane transport [GO:0003333]; choline transport [GO:0015871] GO:0003333; GO:0005307; GO:0005886; GO:0008292; GO:0015171; GO:0015220; GO:0015871; GO:0016020 45892 XM_044320629.1 395 222 121 114 2 NA NA NA NA NA NA 45893 XR_006397015.1 111 122 57 91 167 NA NA NA NA NA NA 45894 XR_003825809.2 69 42 50 56 73 NA NA NA NA NA NA 45895 XM_044329034.1 985 176 256 1119 1612 NA NA NA NA NA NA 45896 XM_044308401.1 32 5 14 36 26 O93403 5.15e-26 Carbohydrate sulfotransferase 3 (EC 2.8.2.17) (EC 2.8.2.21) (Chondroitin 6-O-sulfotransferase 1) (C6ST-1) (Nervous system involved sulfotransferase) Tetronarce californica (Pacific electric ray) (Torpedo californica) carbohydrate metabolic process [GO:0005975]; chondroitin sulfate biosynthetic process [GO:0030206] GO:0000139; GO:0005975; GO:0008459; GO:0030206 45897 XM_044307724.1 0 9 0 6 9 P04323 2.14e-62 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 45898 XR_006394381.1 0 0 0 0 33 NA NA NA NA NA NA 45899 XM_044328727.1 90 23 31 0 74 NA NA NA NA NA NA 45900 XM_029330952.2 351 223 242 262 315 NA NA NA NA NA NA 45901 XM_029323885.2 265 202 167 311 185 F4JTS8 3.07e-134 Protein NO VEIN (Protein EMBRYO DEFECTIVE 2597) Arabidopsis thaliana (Mouse-ear cress) auxin polar transport [GO:0009926]; cell fate specification [GO:0001708]; embryo development ending in seed dormancy [GO:0009793]; leaf vascular tissue pattern formation [GO:0010305]; root development [GO:0048364]; stem cell population maintenance [GO:0019827] GO:0001708; GO:0005634; GO:0009793; GO:0009926; GO:0010305; GO:0019827; GO:0048364 45902 XM_044315707.1 0 0 10 9 21 NA NA NA NA NA NA 45903 XM_029330315.2 1423 793 592 1261 1168 Q3KR37 1.19e-47 Protein Aster-B (GRAM domain-containing protein 1B) Homo sapiens (Human) cellular response to cholesterol [GO:0071397]; cholesterol homeostasis [GO:0042632]; intracellular sterol transport [GO:0032366] GO:0001786; GO:0005789; GO:0005886; GO:0015485; GO:0016020; GO:0032366; GO:0032934; GO:0042632; GO:0070300; GO:0071397; GO:0120015; GO:0120020; GO:0140268 45904 XM_029330315.2 1423 793 592 1261 1168 Q3KR37 5.11e-39 Protein Aster-B (GRAM domain-containing protein 1B) Homo sapiens (Human) cellular response to cholesterol [GO:0071397]; cholesterol homeostasis [GO:0042632]; intracellular sterol transport [GO:0032366] GO:0001786; GO:0005789; GO:0005886; GO:0015485; GO:0016020; GO:0032366; GO:0032934; GO:0042632; GO:0070300; GO:0071397; GO:0120015; GO:0120020; GO:0140268 45905 XM_044318677.1 3 821 820 949 977 Q8IVV2 0 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 45906 XM_044318677.1 3 821 820 949 977 Q8IVV2 1.41e-169 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 45907 XM_044318677.1 3 821 820 949 977 Q8IVV2 2.19e-163 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 45908 XM_044318677.1 3 821 820 949 977 Q8IVV2 3.95e-154 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 45909 XM_044318677.1 3 821 820 949 977 Q8IVV2 2.23e-117 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 45910 XM_044318677.1 3 821 820 949 977 Q8IVV2 1.22e-107 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 45911 XM_044318455.1 593 215 338 424 542 Q32LE5 6e-73 Isoaspartyl peptidase/L-asparaginase (EC 3.4.19.5) (EC 3.5.1.1) (Asparaginase-like protein 1) (Beta-aspartyl-peptidase) (Isoaspartyl dipeptidase) (L-asparagine amidohydrolase) [Cleaved into: Isoaspartyl peptidase/L-asparaginase alpha chain; Isoaspartyl peptidase/L-asparaginase beta chain] Bos taurus (Bovine) asparagine catabolic process via L-aspartate [GO:0033345]; proteolysis [GO:0006508] GO:0001917; GO:0004067; GO:0005737; GO:0006508; GO:0008798; GO:0033345 45912 XM_044318455.1 593 215 338 424 542 Q32LE5 4.47e-70 Isoaspartyl peptidase/L-asparaginase (EC 3.4.19.5) (EC 3.5.1.1) (Asparaginase-like protein 1) (Beta-aspartyl-peptidase) (Isoaspartyl dipeptidase) (L-asparagine amidohydrolase) [Cleaved into: Isoaspartyl peptidase/L-asparaginase alpha chain; Isoaspartyl peptidase/L-asparaginase beta chain] Bos taurus (Bovine) asparagine catabolic process via L-aspartate [GO:0033345]; proteolysis [GO:0006508] GO:0001917; GO:0004067; GO:0005737; GO:0006508; GO:0008798; GO:0033345 45913 XM_044310479.1 44 36 53 480 48 NA NA NA NA NA NA 45914 XR_006394708.1 23 43 0 2 7 P85515 1.85e-26 Alpha-centractin (Centractin) Rattus norvegicus (Rat) spermatogenesis [GO:0007283] GO:0002177; GO:0005524; GO:0005813; GO:0005814; GO:0005938; GO:0007283; GO:0030137 45915 XM_044323619.1 10 4 20 7 11 P0CT40 4.32e-62 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 45916 XM_044325223.1 1824 1962 998 2228 1976 Q791B0 2.44e-27 Ubiquitin-like protein 5 (Beacon protein) Psammomys obesus (Fat sand rat) protein modification process [GO:0036211] GO:0005737; GO:0036211 45917 XM_044315309.1 0 14 0 0 0 A4QNP7 2.03e-29 Doublesex- and mab-3-related transcription factor A2 (Doublesex- and mab-3-related transcription factor 5) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006355; GO:0043565; GO:0046872 45918 XM_029337572.2 1727 2596 1543 2638 1962 Q568D2 8.24e-66 Cilia- and flagella-associated protein 161 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271] GO:0005879; GO:0031514; GO:0060271 45919 XM_029353259.2 103 39 0 0 0 Q8N9I5 5.08e-79 Fatty acid desaturase 6 (EC 1.14.19.-) Homo sapiens (Human) fatty acid biosynthetic process [GO:0006633]; lipid metabolic process [GO:0006629] GO:0006629; GO:0006633; GO:0016020; GO:0016717 45920 XM_029345716.2 327 210 184 267 329 NA NA NA NA NA NA 45921 XR_003824135.2 11 3 0 16 3 NA NA NA NA NA NA 45922 XM_044314034.1 20 0 15 18 98 NA NA NA NA NA NA 45923 XR_006395877.1 0 0 2 4 13 Q3V2Q8 7.48e-47 NEDD4-binding protein 2-like 1 Mus musculus (Mouse) NA NA 45924 XM_044311578.1 105 22 75 161 112 NA NA NA NA NA NA 45925 XM_044323303.1 1191 25 26 254 446 Q9GZV1 2.14e-22 Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp) Homo sapiens (Human) muscle contraction [GO:0006936]; muscle organ development [GO:0007517]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619] GO:0000122; GO:0000791; GO:0005634; GO:0005829; GO:0006357; GO:0006936; GO:0007517; GO:0008307; GO:0016605; GO:0031674; GO:0043231; GO:0043422; GO:0043619; GO:0045662; GO:0061629 45926 XM_029343497.2 141 178 155 131 0 Q9QZS6 6.24e-90 Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (3-OST-3B) (Heparan sulfate 3-O-sulfotransferase 3B1) (m3-OST-3B) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; protein sulfation [GO:0006477] GO:0000139; GO:0001658; GO:0005886; GO:0006024; GO:0006477; GO:0008467; GO:0015012; GO:0033872 45927 XR_006391438.1 11 0 0 1 2 NA NA NA NA NA NA 45928 XM_044310412.1 0 16 14 137 20 NA NA NA NA NA NA 45929 XM_029346035.2 265 246 230 154 125 Q9NYG2 1.42e-47 Palmitoyltransferase ZDHHC3 (EC 2.3.1.225) (Acyltransferase ZDHHC3) (EC 2.3.1.-) (Protein DHHC1) (Zinc finger DHHC domain-containing protein 3) (DHHC-3) Homo sapiens (Human) lipoprotein localization to membrane [GO:0044873]; peptidyl-L-cysteine S-palmitoylation [GO:0018230]; positive regulation of receptor localization to synapse [GO:1902685]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; protein localization to photoreceptor outer segment [GO:1903546]; protein localization to plasma membrane [GO:0072659]; protein palmitoylation [GO:0018345]; protein targeting to membrane [GO:0006612]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; TRAIL-activated apoptotic signaling pathway [GO:0036462] GO:0000139; GO:0005783; GO:0005794; GO:0006612; GO:0008277; GO:0016020; GO:0016409; GO:0018230; GO:0018345; GO:0019705; GO:0019706; GO:0032230; GO:0036462; GO:0042803; GO:0044873; GO:0072659; GO:0140439; GO:1902685; GO:1903546 45930 XM_044316890.1 73 0 0 212 44 Q9GLK0 1.08e-170 Protein-glutamine gamma-glutamyltransferase K (EC 2.3.2.13) (Epidermal TGase) (Transglutaminase K) (TG(K)) (TGK) (TGase K) (Transglutaminase-1) (TGase-1) Canis lupus familiaris (Dog) (Canis familiaris) keratinization [GO:0031424]; peptide cross-linking [GO:0018149]; positive regulation of cell cycle [GO:0045787]; positive regulation of keratinocyte proliferation [GO:0010838] GO:0003810; GO:0010838; GO:0016020; GO:0018149; GO:0031424; GO:0045787; GO:0046872 45931 XR_003825763.2 12 0 3 0 15 NA NA NA NA NA NA 45932 XM_044326026.1 1204 638 730 981 1301 Q5R539 3.82e-140 Serrate RNA effector molecule homolog (Arsenite-resistance protein 2) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) mRNA processing [GO:0006397]; neuronal stem cell population maintenance [GO:0097150]; primary miRNA processing [GO:0031053]; regulation of DNA-templated transcription [GO:0006355] GO:0003677; GO:0005654; GO:0005737; GO:0006355; GO:0006397; GO:0031053; GO:0097150 45933 XM_044326026.1 1204 638 730 981 1301 Q5R539 1.25e-39 Serrate RNA effector molecule homolog (Arsenite-resistance protein 2) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) mRNA processing [GO:0006397]; neuronal stem cell population maintenance [GO:0097150]; primary miRNA processing [GO:0031053]; regulation of DNA-templated transcription [GO:0006355] GO:0003677; GO:0005654; GO:0005737; GO:0006355; GO:0006397; GO:0031053; GO:0097150 45934 XR_003828179.2 51 23 24 73 31 NA NA NA NA NA NA 45935 XM_044324720.1 0 29 151 48 193 P07949 6.45e-82 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; axon guidance [GO:0007411]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; lymphocyte migration into lymphoid organs [GO:0097021]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; posterior midgut development [GO:0007497]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006468; GO:0006919; GO:0007156; GO:0007158; GO:0007165; GO:0007169; GO:0007411; GO:0007497; GO:0009410; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0038023; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0097021; GO:0098797; GO:2001241 45936 XM_029333430.2 3375 3733 2657 2329 1370 NA NA NA NA NA NA 45937 XM_044323488.1 18 8 7 14 0 NA NA NA NA NA NA 45938 XM_044323113.1 1703 1642 1118 1884 2612 Q5RKH6 6.81e-40 Protein OS-9 Rattus norvegicus (Rat) endoplasmic reticulum unfolded protein response [GO:0030968]; negative regulation of retrograde protein transport, ER to cytosol [GO:1904153]; protein retention in ER lumen [GO:0006621]; protein targeting [GO:0006605]; protein ubiquitination [GO:0016567]; response to endoplasmic reticulum stress [GO:0034976]; retrograde protein transport, ER to cytosol [GO:0030970]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0002020; GO:0005783; GO:0005788; GO:0006511; GO:0006605; GO:0006621; GO:0016567; GO:0030246; GO:0030433; GO:0030968; GO:0030970; GO:0034976; GO:1904153 45939 XM_029331039.2 609 1086 432 799 583 Q6Q2B2 5.03e-60 Muscleblind-like protein 2a (Tmbnl2a) Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0003723; GO:0005634; GO:0005737; GO:0006397; GO:0008380; GO:0046872 45940 XM_044322995.1 0 0 0 45 0 NA NA NA NA NA NA 45941 XM_029351053.2 826 812 547 396 398 E7FAM5 6.85e-54 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 45942 XM_029351053.2 826 812 547 396 398 E7FAM5 1.16e-52 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 45943 XM_044325362.1 0 266 82 257 68 NA NA NA NA NA NA 45944 XM_029357602.2 142 223 178 76 58 Q91XV4 2e-104 L-xylulose reductase (XR) (EC 1.1.1.10) (Dicarbonyl/L-xylulose reductase) (Sperm antigen P26h) Mesocricetus auratus (Golden hamster) D-xylose metabolic process [GO:0042732]; glucose metabolic process [GO:0006006]; glucuronate catabolic process to xylulose 5-phosphate [GO:0019640]; NADP metabolic process [GO:0006739]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; xylulose metabolic process [GO:0005997] GO:0001669; GO:0005829; GO:0005881; GO:0005902; GO:0005903; GO:0005997; GO:0006006; GO:0006739; GO:0016020; GO:0016655; GO:0019640; GO:0042732; GO:0042802; GO:0050038; GO:2000379 45945 XM_029332571.2 122 132 92 203 230 NA NA NA NA NA NA 45946 XM_029331117.2 2598 1597 1533 2475 2157 Q6F3J0 3.57e-165 Nuclear factor NF-kappa-B p105 subunit (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit] Canis lupus familiaris (Dog) (Canis familiaris) negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165] GO:0000122; GO:0000976; GO:0000978; GO:0000981; GO:0003700; GO:0005634; GO:0005737; GO:0006357; GO:0007165; GO:0045893 45947 XM_044321328.1 60 45 138 106 199 O00370 4.77e-28 LINE-1 retrotransposable element ORF2 protein (ORF2p) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)] Homo sapiens (Human) DNA recombination [GO:0006310]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; reverse transcription involved in RNA-mediated transposition [GO:0032199]; transposition, RNA-mediated [GO:0032197] GO:0003723; GO:0003964; GO:0006310; GO:0009036; GO:0032197; GO:0032199; GO:0046872; GO:0090305 45948 XR_006392592.1 15 0 0 13 0 NA NA NA NA NA NA 45949 XM_044326711.1 1125 719 823 1544 1921 D3YXG0 0 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 45950 XM_044326711.1 1125 719 823 1544 1921 D3YXG0 0 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 45951 XM_044326711.1 1125 719 823 1544 1921 D3YXG0 0 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 45952 XM_044326711.1 1125 719 823 1544 1921 D3YXG0 0 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 45953 XM_044326711.1 1125 719 823 1544 1921 D3YXG0 3.7e-79 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 45954 XM_044309048.1 1137 2100 745 953 565 NA NA NA NA NA NA 45955 XM_029334759.2 12 314 4 270 35 NA NA NA NA NA NA 45956 XM_044316785.1 216 131 140 138 162 Q1LUI2 5.16e-70 5'-deoxynucleotidase HDDC2 (EC 3.1.3.89) (HD domain-containing protein 2) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0002953; GO:0046872 45957 XM_044307381.1 143 155 28 124 160 NA NA NA NA NA NA 45958 XM_029329266.2 1147 856 668 758 1387 Q9Y2V2 2.1e-37 Calcium-regulated heat-stable protein 1 (Calcium-regulated heat-stable protein of 24 kDa) (CRHSP-24) Homo sapiens (Human) intracellular signal transduction [GO:0035556]; regulation of mRNA stability [GO:0043488] GO:0000177; GO:0000932; GO:0003730; GO:0005737; GO:0005829; GO:0019902; GO:0035556; GO:0043186; GO:0043488 45959 XM_029349020.2 726 1144 609 650 955 P0DMQ6 1.56e-140 Sorbitol dehydrogenase (SDH) (EC 1.1.1.-) (Polyol dehydrogenase) Gallus gallus (Chicken) fructose biosynthetic process [GO:0046370]; fructose metabolic process [GO:0006000]; NADH oxidation [GO:0006116]; NADH regeneration [GO:0006735]; sorbitol biosynthetic process [GO:0006061]; sorbitol catabolic process [GO:0006062] GO:0003939; GO:0006000; GO:0006061; GO:0006062; GO:0006116; GO:0006735; GO:0008270; GO:0031514; GO:0031966; GO:0032991; GO:0046370; GO:0051287 45960 XM_044328114.1 28 0 15 1 0 NA NA NA NA NA NA 45961 XM_029346451.2 7 9 15 7 25 E9Q3T6 6.86e-124 PR domain zinc finger protein 14 (EC 2.1.1.-) (PR domain-containing protein 14) Mus musculus (Mouse) cell fate specification [GO:0001708]; cell morphogenesis [GO:0000902]; embryo implantation [GO:0007566]; epigenetic regulation of gene expression [GO:0040029]; fertilization [GO:0009566]; fibroblast growth factor receptor signaling pathway [GO:0008543]; germ cell development [GO:0007281]; germ-line stem cell population maintenance [GO:0030718]; histone H3-R26 methylation [GO:0034972]; homeostasis of number of cells within a tissue [GO:0048873]; inactivation of paternal X chromosome [GO:0060817]; inner cell mass cell fate commitment [GO:0001827]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of flagellated sperm motility [GO:1902093]; positive regulation of stem cell population maintenance [GO:1902459]; regulation of DNA methylation [GO:0044030]; regulation of gene expression [GO:0010468]; regulation of transcription by RNA polymerase II [GO:0006357]; stem cell population maintenance [GO:0019827] GO:0000122; GO:0000902; GO:0000977; GO:0001227; GO:0001708; GO:0001827; GO:0003723; GO:0005634; GO:0005654; GO:0006357; GO:0007281; GO:0007566; GO:0008168; GO:0008543; GO:0009566; GO:0010468; GO:0019827; GO:0030718; GO:0031490; GO:0034972; GO:0040029; GO:0040037; GO:0044030; GO:0046872; GO:0048873; GO:0060817; GO:1902093; GO:1902459 45962 XM_029323407.2 26 13 28 55 33 NA NA NA NA NA NA 45963 XM_044311031.1 1400 1964 1270 1684 1542 P61227 1.19e-78 Ras-related protein Rap-2b (EC 3.6.5.2) Rattus norvegicus (Rat) negative regulation of cell migration [GO:0030336]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; positive regulation of protein autophosphorylation [GO:0031954]; Rap protein signal transduction [GO:0032486]; regulation of protein tyrosine kinase activity [GO:0061097] GO:0003924; GO:0003925; GO:0005525; GO:0005829; GO:0005886; GO:0005923; GO:0016020; GO:0019003; GO:0019904; GO:0030168; GO:0030336; GO:0031954; GO:0032486; GO:0044291; GO:0045121; GO:0055037; GO:0055038; GO:0061097; GO:0070062; GO:0070527 45964 XM_029348377.2 16 0 0 0 2 NA NA NA NA NA NA 45965 XR_003825752.2 516 0 130 792 1023 Q96MU7 1.01e-58 YTH domain-containing protein 1 (Splicing factor YT521) (YT521-B) Homo sapiens (Human) dosage compensation by inactivation of X chromosome [GO:0009048]; in utero embryonic development [GO:0001701]; mRNA alternative polyadenylation [GO:0110104]; mRNA export from nucleus [GO:0006406]; mRNA splice site selection [GO:0006376]; mRNA splicing, via spliceosome [GO:0000398]; post-transcriptional regulation of gene expression [GO:0010608]; primary follicle stage [GO:0048160]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of mRNA splicing, via spliceosome [GO:0048024]; spermatogenesis [GO:0007283] GO:0000381; GO:0000398; GO:0001701; GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0005886; GO:0006376; GO:0006406; GO:0007283; GO:0009048; GO:0010608; GO:0016607; GO:0048024; GO:0048160; GO:0110104; GO:1990247 45966 XM_029340104.2 0 0 85 174 116 Q05688 8.54e-74 Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Bos taurus (Bovine) cellular response to glucose stimulus [GO:0071333]; glucose homeostasis [GO:0042593]; insulin-like growth factor receptor signaling pathway [GO:0048009]; negative regulation of apoptotic process [GO:0043066]; negative regulation of MAPK cascade [GO:0043409]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; protein autophosphorylation [GO:0046777]; regulation of JNK cascade [GO:0046328]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0004713; GO:0004714; GO:0005009; GO:0005010; GO:0005198; GO:0005520; GO:0005524; GO:0005737; GO:0005886; GO:0005899; GO:0007169; GO:0014068; GO:0030424; GO:0033674; GO:0042593; GO:0043066; GO:0043235; GO:0043409; GO:0043410; GO:0043548; GO:0043560; GO:0046328; GO:0046777; GO:0048009; GO:0051897; GO:0071333 45967 XM_029332260.2 321 257 159 194 237 Q9HCD5 3.06e-35 Nuclear receptor coactivator 5 (NCoA-5) (Coactivator independent of AF-2) (CIA) Homo sapiens (Human) glucose homeostasis [GO:0042593]; insulin receptor signaling pathway [GO:0008286]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of signal transduction [GO:0009966] GO:0000122; GO:0003682; GO:0003714; GO:0003723; GO:0005615; GO:0005654; GO:0008286; GO:0009966; GO:0015629; GO:0042593; GO:0046627 45968 XM_044322849.1 0 0 474 0 0 Q5U584 3.36e-58 SH3 domain-binding protein 5-like (SH3BP-5-like) Xenopus laevis (African clawed frog) intracellular signal transduction [GO:0035556] GO:0005085; GO:0035556 45969 XM_044317429.1 431 565 355 264 570 NA NA NA NA NA NA 45970 XM_044317598.1 733 16 423 22 25 NA NA NA NA NA NA 45971 XM_029343213.2 113 102 64 152 355 Q96M89 6.48e-99 Coiled-coil domain-containing protein 138 Homo sapiens (Human) NA NA 45972 XM_044327864.1 4 0 16 20 28 NA NA NA NA NA NA 45973 XM_029338716.2 15 0 61 23 61 NA NA NA NA NA NA 45974 XR_003825419.2 2779 3463 1456 2092 1503 NA NA NA NA NA NA 45975 XM_044323950.1 24 8 21 12 84 B8VIU6 7.1e-45 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 45976 XM_029338525.2 85 56 143 59 257 A2BGR3 0 DNA excision repair protein ERCC-6-like (EC 3.6.4.12) (ATP-dependent helicase ERCC6-like) Danio rerio (Zebrafish) (Brachydanio rerio) cell cycle [GO:0007049]; cell division [GO:0051301]; intein-mediated protein splicing [GO:0016539] GO:0000776; GO:0003677; GO:0004386; GO:0005524; GO:0007049; GO:0015616; GO:0016539; GO:0016887; GO:0051301; GO:0140658 45977 XM_044310004.1 151 133 91 415 252 O54697 6.08e-124 Aminopeptidase NAALADL1 (EC 3.4.11.-) (100 kDa ileum brush border membrane protein) (I100) (Ileal dipeptidylpeptidase) (N-acetylated-alpha-linked acidic dipeptidase-like protein) (NAALADase L) Rattus norvegicus (Rat) peptide catabolic process [GO:0043171]; proteolysis [GO:0006508] GO:0004177; GO:0004180; GO:0005509; GO:0006508; GO:0008237; GO:0008270; GO:0016020; GO:0016324; GO:0042803; GO:0043171 45978 XM_029341186.2 118 0 0 294 0 Q62717 0 Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1) (rCAPS) Rattus norvegicus (Rat) catecholamine secretion [GO:0050432]; establishment of localization in cell [GO:0051649]; exocytosis [GO:0006887]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of exocytosis [GO:0045921]; presynaptic dense core vesicle exocytosis [GO:0099525]; protein transport [GO:0015031]; regulated exocytosis [GO:0045055]; synaptic vesicle priming [GO:0016082]; vesicle organization [GO:0016050] GO:0005509; GO:0005546; GO:0006887; GO:0015031; GO:0016050; GO:0016082; GO:0019901; GO:0031045; GO:0031410; GO:0045055; GO:0045921; GO:0045956; GO:0050432; GO:0051649; GO:0098674; GO:0098793; GO:0098978; GO:0099525 45979 XM_044325128.1 217 106 20 89 33 Q803I2 0 Endoplasmic reticulum-Golgi intermediate compartment protein 3 Danio rerio (Zebrafish) (Brachydanio rerio) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] GO:0000139; GO:0005783; GO:0005789; GO:0006888; GO:0006890; GO:0016020; GO:0030134; GO:0033116 45980 XM_044314950.1 67 22 74 28 295 Q9DEY9 5.07e-41 RecQ-like DNA helicase BLM (EC 3.6.4.12) (Bloom syndrome protein homolog) (xBLM) (RecQ helicase homolog) Xenopus laevis (African clawed frog) DNA double-strand break processing [GO:0000729]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA replication [GO:0006260]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of DNA-templated DNA replication [GO:0090329] GO:0000400; GO:0000729; GO:0003677; GO:0003678; GO:0003697; GO:0005524; GO:0005634; GO:0006260; GO:0006310; GO:0008094; GO:0008270; GO:0009378; GO:0016887; GO:0032508; GO:0042803; GO:0043138; GO:0051259; GO:0051260; GO:0061749; GO:0090329 45981 XM_029328525.2 17109 21889 7911 14180 13147 Q90YV5 3.56e-82 60S ribosomal protein L13 Ictalurus punctatus (Channel catfish) (Silurus punctatus) translation [GO:0006412] GO:0003735; GO:0005737; GO:0005840; GO:0006412; GO:1990904 45982 XM_029330390.2 2826 2451 2714 3963 2536 Q5U239 9.6e-126 Transmembrane protein 145 Xenopus laevis (African clawed frog) G protein-coupled receptor signaling pathway [GO:0007186]; response to pheromone [GO:0019236] GO:0007186; GO:0016020; GO:0019236 45983 XM_029351154.2 0 51 0 0 0 Q80T21 6.56e-118 ADAMTS-like protein 4 (ADAMTSL-4) (Thrombospondin repeat-containing protein 1) Mus musculus (Mouse) apoptotic process [GO:0006915]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; pigment cell development [GO:0070285]; positive regulation of apoptotic process [GO:0043065] GO:0002020; GO:0002064; GO:0005576; GO:0005614; GO:0006915; GO:0030198; GO:0031012; GO:0042802; GO:0043065; GO:0070285 45984 XM_029344471.2 238 373 273 107 83 P50238 2.15e-21 Cysteine-rich protein 1 (CRP-1) (Cysteine-rich heart protein) (CRHP) (hCRHP) (Cysteine-rich intestinal protein) (CRIP) Homo sapiens (Human) cellular response to antibiotic [GO:0071236]; cellular response to UV-B [GO:0071493]; heart development [GO:0007507]; immune response [GO:0006955]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; prostate gland stromal morphogenesis [GO:0060741]; regulation of gene expression [GO:0010468]; response to organic substance [GO:0010033]; response to zinc ion [GO:0010043] GO:0005737; GO:0006955; GO:0007507; GO:0008270; GO:0008630; GO:0010033; GO:0010043; GO:0010468; GO:0042277; GO:0060741; GO:0071236; GO:0071493 45985 XM_029345448.2 122 87 15 29 25 NA NA NA NA NA NA 45986 XM_029328779.2 826 601 447 1018 1067 Q9CWK3 1.02e-51 CD2 antigen cytoplasmic tail-binding protein 2 (CD2 cytoplasmic domain-binding protein 2) (CD2 tail-binding protein 2) Mus musculus (Mouse) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0001650; GO:0005634; GO:0005654; GO:0005682; GO:0005829; GO:0006397; GO:0008380; GO:0016607; GO:0043021 45987 XM_029341431.2 310 350 140 297 406 Q64332 3.27e-134 Synapsin-2 (Synapsin II) Mus musculus (Mouse) calcium-ion regulated exocytosis [GO:0017156]; neurotransmitter secretion [GO:0007269]; synaptic vesicle clustering [GO:0097091]; synaptic vesicle cycle [GO:0099504] GO:0005524; GO:0005886; GO:0007269; GO:0008021; GO:0014069; GO:0017156; GO:0030672; GO:0031201; GO:0042802; GO:0043209; GO:0045202; GO:0048306; GO:0097091; GO:0098685; GO:0098850; GO:0098978; GO:0099504 45988 XR_006395982.1 283 236 348 165 240 NA NA NA NA NA NA 45989 XM_029348833.2 60 0 0 0 89 Q86V88 4.51e-50 Magnesium-dependent phosphatase 1 (MDP-1) (EC 3.1.3.-) (EC 3.1.3.48) Homo sapiens (Human) NA GO:0003993; GO:0004725; GO:0046872 45990 XM_044311121.1 152 556 181 218 109 NA NA NA NA NA NA 45991 XR_006392985.1 41 2 25 5 151 NA NA NA NA NA NA 45992 XM_029351413.2 133 62 83 56 29 O60282 0 Kinesin heavy chain isoform 5C (EC 3.6.4.-) (Kinesin heavy chain neuron-specific 2) (Kinesin-1) Homo sapiens (Human) anterograde axonal protein transport [GO:0099641]; anterograde dendritic transport of neurotransmitter receptor complex [GO:0098971]; axon guidance [GO:0007411]; cytoskeleton-dependent intracellular transport [GO:0030705]; microtubule-based movement [GO:0007018]; motor neuron axon guidance [GO:0008045]; mRNA transport [GO:0051028]; organelle organization [GO:0006996]; synaptic vesicle transport [GO:0048489] GO:0003777; GO:0005524; GO:0005871; GO:0005874; GO:0006996; GO:0007018; GO:0007411; GO:0008017; GO:0008045; GO:0008574; GO:0016887; GO:0030705; GO:0032839; GO:0035253; GO:0043025; GO:0044295; GO:0048489; GO:0051028; GO:0098971; GO:0099641; GO:0150034; GO:1904115 45993 XM_044309299.1 142 14 31 0 1086 Q80X72 2.04e-25 Leucine-rich repeat-containing protein 15 Mus musculus (Mouse) negative regulation of protein localization to plasma membrane [GO:1903077]; positive regulation of cell migration [GO:0030335]; receptor-mediated virion attachment to host cell [GO:0046813] GO:0001968; GO:0005518; GO:0005615; GO:0009986; GO:0016020; GO:0030335; GO:0031012; GO:0043236; GO:0046813; GO:0062023; GO:1903077 45994 XM_044309299.1 142 14 31 0 1086 Q80X72 3.87e-24 Leucine-rich repeat-containing protein 15 Mus musculus (Mouse) negative regulation of protein localization to plasma membrane [GO:1903077]; positive regulation of cell migration [GO:0030335]; receptor-mediated virion attachment to host cell [GO:0046813] GO:0001968; GO:0005518; GO:0005615; GO:0009986; GO:0016020; GO:0030335; GO:0031012; GO:0043236; GO:0046813; GO:0062023; GO:1903077 45995 XM_044309299.1 142 14 31 0 1086 Q80X72 1.6e-21 Leucine-rich repeat-containing protein 15 Mus musculus (Mouse) negative regulation of protein localization to plasma membrane [GO:1903077]; positive regulation of cell migration [GO:0030335]; receptor-mediated virion attachment to host cell [GO:0046813] GO:0001968; GO:0005518; GO:0005615; GO:0009986; GO:0016020; GO:0030335; GO:0031012; GO:0043236; GO:0046813; GO:0062023; GO:1903077 45996 XM_029347456.2 175 367 164 159 190 P48039 1.89e-23 Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor) Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; circadian rhythm [GO:0007623]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; mating behavior [GO:0007617] GO:0004930; GO:0005886; GO:0007186; GO:0007187; GO:0007193; GO:0007617; GO:0007623; GO:0008502; GO:0042562; GO:0043235; GO:0097159 45997 XR_006393831.1 23 12 1 121 14 NA NA NA NA NA NA 45998 XM_029344535.2 710 453 552 733 628 O77457 6.42e-150 Tryptophan 2,3-dioxygenase (TDO) (EC 1.13.11.11) (Tryptamin 2,3-dioxygenase) (Tryptophan oxygenase) (TO) (TRPO) (Tryptophan pyrrolase) (Tryptophanase) Anopheles gambiae (African malaria mosquito) ommochrome biosynthetic process [GO:0006727]; tryptophan catabolic process to acetyl-CoA [GO:0019442]; tryptophan catabolic process to kynurenine [GO:0019441] GO:0004833; GO:0006727; GO:0019441; GO:0019442; GO:0020037; GO:0046872 45999 XM_044316165.1 333 130 132 157 286 Q02241 0 Kinesin-like protein KIF23 (Kinesin-like protein 5) (Mitotic kinesin-like protein 1) Homo sapiens (Human) microtubule-based movement [GO:0007018]; mitotic cytokinesis [GO:0000281]; mitotic spindle elongation [GO:0000022]; mitotic spindle midzone assembly [GO:0051256]; positive regulation of cytokinesis [GO:0032467] GO:0000022; GO:0000281; GO:0003777; GO:0005524; GO:0005634; GO:0005654; GO:0005813; GO:0005819; GO:0005829; GO:0005871; GO:0005874; GO:0005925; GO:0007018; GO:0008017; GO:0016887; GO:0030496; GO:0032467; GO:0051256; GO:0072686; GO:0090543; GO:0097149 46000 XM_044316165.1 333 130 132 157 286 Q02241 1.62e-28 Kinesin-like protein KIF23 (Kinesin-like protein 5) (Mitotic kinesin-like protein 1) Homo sapiens (Human) microtubule-based movement [GO:0007018]; mitotic cytokinesis [GO:0000281]; mitotic spindle elongation [GO:0000022]; mitotic spindle midzone assembly [GO:0051256]; positive regulation of cytokinesis [GO:0032467] GO:0000022; GO:0000281; GO:0003777; GO:0005524; GO:0005634; GO:0005654; GO:0005813; GO:0005819; GO:0005829; GO:0005871; GO:0005874; GO:0005925; GO:0007018; GO:0008017; GO:0016887; GO:0030496; GO:0032467; GO:0051256; GO:0072686; GO:0090543; GO:0097149 46001 XM_044325297.1 4 9 1 8 20 NA NA NA NA NA NA 46002 XM_044326728.1 0 3 0 8 3 NA NA NA NA NA NA 46003 XM_044324739.1 1512 1064 676 1254 1351 Q91857 7.26e-164 Transcription initiation factor TFIID subunit 6 (xTAF6) (Transcription initiation factor TFIID 60 kDa subunit) (TAF(II)60) (TAFII-60) (TAFII60) (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII70) Xenopus laevis (African clawed frog) transcription initiation at RNA polymerase II promoter [GO:0006367] GO:0000124; GO:0005669; GO:0006367; GO:0016251; GO:0046695; GO:0046982; GO:0071339 46004 XM_044312277.1 15 0 8 14 7 NA NA NA NA NA NA 46005 XM_044314473.1 156 92 220 499 287 NA NA NA NA NA NA 46006 XM_044309454.1 446 285 224 0 0 NA NA NA NA NA NA 46007 XR_006396792.1 59 269 115 179 187 NA NA NA NA NA NA 46008 XM_029334781.2 592 505 435 501 559 Q8WV07 6.26e-25 Protein LTO1 homolog (Oral cancer-overexpressed protein 1) (Tumor-amplified and overexpressed sequence 1) Homo sapiens (Human) protein maturation by [4Fe-4S] cluster transfer [GO:0106035]; ribosomal large subunit biogenesis [GO:0042273]; telomere maintenance [GO:0000723]; translational initiation [GO:0006413] GO:0000723; GO:0005634; GO:0006413; GO:0042273; GO:0106035 46009 XM_029329917.2 9182 10166 4390 5927 5100 O18334 1.87e-118 Ras-related protein Rab6 (Protein warthog) Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; compound eye morphogenesis [GO:0001745]; defense response to fungus [GO:0050832]; exocytosis [GO:0006887]; germarium-derived egg chamber formation [GO:0007293]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; oocyte microtubule cytoskeleton polarization [GO:0008103]; phototransduction [GO:0007602]; pole plasm oskar mRNA localization [GO:0045451]; protein targeting to Golgi apparatus [GO:0140450]; R7 cell development [GO:0045467]; Rab protein signal transduction [GO:0032482]; receptor recycling [GO:0001881]; regulation of postsynaptic membrane potential [GO:0060078]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0001745; GO:0001881; GO:0003779; GO:0003924; GO:0005525; GO:0005764; GO:0005776; GO:0005794; GO:0005829; GO:0006886; GO:0006887; GO:0006890; GO:0006891; GO:0007293; GO:0007411; GO:0007602; GO:0008103; GO:0012505; GO:0016192; GO:0031410; GO:0032482; GO:0042147; GO:0043025; GO:0043204; GO:0045202; GO:0045451; GO:0045467; GO:0050832; GO:0060078; GO:0140450 46010 XM_029353200.2 8 19 1 8 26 Q9CQ52 5.73e-52 Chymotrypsin-like elastase family member 3B (EC 3.4.21.70) (Elastase IIIB) (Elastase-3B) (Protease E) Mus musculus (Mouse) proteolysis [GO:0006508] GO:0004252; GO:0005615; GO:0006508; GO:0062023 46011 XR_003827426.2 426 216 543 343 1295 NA NA NA NA NA NA 46012 XR_003826703.2 47 116 10 132 206 P0CI65 4.82e-46 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 46013 XR_003826703.2 47 116 10 132 206 P0CI65 2.16e-41 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 46014 XR_003826703.2 47 116 10 132 206 P0CI65 2.4e-38 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 46015 XR_003826703.2 47 116 10 132 206 P0CI65 4.02e-36 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 46016 XR_003826703.2 47 116 10 132 206 P0CI65 6.8e-31 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 46017 XM_044328887.1 37 25 45 155 56 NA NA NA NA NA NA 46018 XM_029324982.2 103 76 58 87 159 NA NA NA NA NA NA 46019 XM_029335000.2 422 202 134 459 929 E2JA28 8.99e-33 Dapdiamide synthesis protein DdaC (EC 1.-.-.-) Enterobacter agglomerans (Erwinia herbicola) (Pantoea agglomerans) antibiotic biosynthetic process [GO:0017000] GO:0016491; GO:0017000 46020 XM_029352476.2 7262 7202 2825 6952 5880 Q5R546 0 ATP synthase subunit alpha, mitochondrial (ATP synthase F1 subunit alpha) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) lipid metabolic process [GO:0006629]; negative regulation of endothelial cell proliferation [GO:0001937]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776] GO:0001937; GO:0005524; GO:0005753; GO:0005886; GO:0006629; GO:0008180; GO:0042288; GO:0042776; GO:0043532; GO:0043536; GO:0045261; GO:0046933 46021 XR_003824165.2 31 37 14 21 22 Q91WE2 5.75e-25 PSME3-interacting protein (NEFA-interacting nuclear protein NIP30) (PA28G-interacting protein) Mus musculus (Mouse) negative regulation of proteasomal protein catabolic process [GO:1901799]; negative regulation of protein binding [GO:0032091] GO:0005634; GO:0032091; GO:1901799 46022 XR_003823139.1 2 1 12 2 23 NA NA NA NA NA NA 46023 XM_044320725.1 5 0 3 3 8 M9NDE3 3.42e-29 Protein bark beetle (Protein anakonda) Drosophila melanogaster (Fruit fly) cell-cell junction maintenance [GO:0045217]; liquid clearance, open tracheal system [GO:0035002]; regulation of tube length, open tracheal system [GO:0035159]; response to endoplasmic reticulum stress [GO:0034976]; tricellular tight junction assembly [GO:1904274] GO:0005044; GO:0005912; GO:0005918; GO:0005923; GO:0016328; GO:0030246; GO:0034976; GO:0035002; GO:0035159; GO:0045217; GO:0061689; GO:1904274 46024 XM_044319539.1 7543 4163 2291 6749 4698 O76082 1.38e-58 Organic cation/carnitine transporter 2 (High-affinity sodium-dependent carnitine cotransporter) (Solute carrier family 22 member 5) Homo sapiens (Human) (R)-carnitine transmembrane transport [GO:1902270]; (R)-carnitine transport [GO:1900749]; carnitine transmembrane transport [GO:1902603]; carnitine transport [GO:0015879]; positive regulation of intestinal epithelial structure maintenance [GO:0060731]; quaternary ammonium group transport [GO:0015697]; response to symbiotic bacterium [GO:0009609]; response to tumor necrosis factor [GO:0034612]; response to type II interferon [GO:0034341]; sodium ion transport [GO:0006814]; sodium-dependent organic cation transport [GO:0070715]; transport across blood-brain barrier [GO:0150104]; xenobiotic detoxification by transmembrane export across the plasma membrane [GO:1990961] GO:0005524; GO:0005737; GO:0005783; GO:0005829; GO:0005886; GO:0006814; GO:0009609; GO:0009925; GO:0015226; GO:0015293; GO:0015651; GO:0015697; GO:0015879; GO:0016324; GO:0030165; GO:0031526; GO:0034341; GO:0034612; GO:0042910; GO:0060731; GO:0070062; GO:0070715; GO:0150104; GO:1900749; GO:1901235; GO:1902270; GO:1902603; GO:1990961 46025 XM_044319539.1 7543 4163 2291 6749 4698 O76082 5.36e-48 Organic cation/carnitine transporter 2 (High-affinity sodium-dependent carnitine cotransporter) (Solute carrier family 22 member 5) Homo sapiens (Human) (R)-carnitine transmembrane transport [GO:1902270]; (R)-carnitine transport [GO:1900749]; carnitine transmembrane transport [GO:1902603]; carnitine transport [GO:0015879]; positive regulation of intestinal epithelial structure maintenance [GO:0060731]; quaternary ammonium group transport [GO:0015697]; response to symbiotic bacterium [GO:0009609]; response to tumor necrosis factor [GO:0034612]; response to type II interferon [GO:0034341]; sodium ion transport [GO:0006814]; sodium-dependent organic cation transport [GO:0070715]; transport across blood-brain barrier [GO:0150104]; xenobiotic detoxification by transmembrane export across the plasma membrane [GO:1990961] GO:0005524; GO:0005737; GO:0005783; GO:0005829; GO:0005886; GO:0006814; GO:0009609; GO:0009925; GO:0015226; GO:0015293; GO:0015651; GO:0015697; GO:0015879; GO:0016324; GO:0030165; GO:0031526; GO:0034341; GO:0034612; GO:0042910; GO:0060731; GO:0070062; GO:0070715; GO:0150104; GO:1900749; GO:1901235; GO:1902270; GO:1902603; GO:1990961 46026 XM_029331254.2 1841 2481 1512 2316 1125 P79888 1.32e-99 S-adenosylmethionine decarboxylase proenzyme (AdoMetDC) (SAMDC) (EC 4.1.1.50) [Cleaved into: S-adenosylmethionine decarboxylase alpha chain; S-adenosylmethionine decarboxylase beta chain] Xenopus laevis (African clawed frog) spermidine biosynthetic process [GO:0008295]; spermine biosynthetic process [GO:0006597] GO:0004014; GO:0006597; GO:0008295 46027 XM_044326320.1 36 9 35 0 155 NA NA NA NA NA NA 46028 XR_006394109.1 0 0 0 8 0 NA NA NA NA NA NA 46029 XM_044308096.1 896 544 523 1340 773 P25439 0 ATP-dependent helicase brm (EC 3.6.4.12) (Homeotic gene regulator) (Protein brahma) Drosophila melanogaster (Fruit fly) axonogenesis [GO:0007409]; cell dedifferentiation [GO:0043697]; chromatin remodeling [GO:0006338]; dendrite guidance [GO:0070983]; dendrite morphogenesis [GO:0048813]; hemocyte proliferation [GO:0035172]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of neuroblast proliferation [GO:0007406]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of innate immune response [GO:0045088]; regulation of neuroblast proliferation [GO:1902692]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription initiation-coupled chromatin remodeling [GO:0045815]; ventral cord development [GO:0007419] GO:0001223; GO:0003677; GO:0004386; GO:0005524; GO:0005634; GO:0005700; GO:0006338; GO:0006357; GO:0007406; GO:0007409; GO:0007419; GO:0007474; GO:0008094; GO:0008586; GO:0008587; GO:0016887; GO:0035060; GO:0035172; GO:0036335; GO:0042393; GO:0043697; GO:0045088; GO:0045815; GO:0045893; GO:0045944; GO:0048813; GO:0070983; GO:0140297; GO:0140566; GO:0140658; GO:1902692; GO:2000134; GO:2000648 46030 XM_044324120.1 0 0 7 70 9 NA NA NA NA NA NA 46031 XM_029338413.2 3185 4703 4151 6244 12729 Q14BV6 6.76e-95 Carbohydrate deacetylase (EC 3.5.1.-) Mus musculus (Mouse) carbohydrate metabolic process [GO:0005975] GO:0000287; GO:0005975; GO:0019213 46032 XM_044314151.1 11 0 3 5 11 NA NA NA NA NA NA 46033 XM_044328474.1 45 18 40 94 34 NA NA NA NA NA NA 46034 XR_003827887.2 155 72 80 56 69 NA NA NA NA NA NA 46035 XM_044328675.1 24 49 6 38 33 O43827 5.93e-35 Angiopoietin-related protein 7 (Angiopoietin-like factor) (Angiopoietin-like protein 7) (Cornea-derived transcript 6 protein) Homo sapiens (Human) negative regulation of vasculature development involved in avascular cornea development in camera-type eye [GO:1901346]; regulation of extracellular matrix organization [GO:1903053]; response to oxidative stress [GO:0006979] GO:0005102; GO:0005576; GO:0005615; GO:0006979; GO:0042802; GO:0062023; GO:1901346; GO:1903053 46036 XM_029333872.2 1068 764 239 456 212 P34949 5.48e-137 Mannose-6-phosphate isomerase (EC 5.3.1.8) (Phosphohexomutase) (Phosphomannose isomerase) (PMI) Homo sapiens (Human) GDP-mannose biosynthetic process [GO:0009298]; mannose to fructose-6-phosphate metabolic process [GO:0061611] GO:0004476; GO:0005829; GO:0008270; GO:0009298; GO:0061611; GO:0070062 46037 XM_044306906.1 31 78 8 34 46 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 46038 XM_044306906.1 31 78 8 34 46 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 46039 XM_044306906.1 31 78 8 34 46 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 46040 XM_044306906.1 31 78 8 34 46 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 46041 XM_044306906.1 31 78 8 34 46 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 46042 XM_044306906.1 31 78 8 34 46 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 46043 XM_044306906.1 31 78 8 34 46 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 46044 XM_044306906.1 31 78 8 34 46 P07207 2.53e-173 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 46045 XM_044306906.1 31 78 8 34 46 P07207 2.31e-136 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 46046 XM_029344093.2 0 0 9 0 61 Q6RI86 1.27e-81 Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Wasabi receptor) Rattus norvegicus (Rat) calcium ion transmembrane import into cytosol [GO:0097553]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cell surface receptor signaling pathway [GO:0007166]; cellular calcium ion homeostasis [GO:0006874]; cellular response to caffeine [GO:0071313]; cellular response to carbon dioxide [GO:0071244]; cellular response to cold [GO:0070417]; cellular response to heat [GO:0034605]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to organic substance [GO:0071310]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; ion transmembrane transport [GO:0034220]; positive regulation of anion transport [GO:1903793]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of sensory perception of pain [GO:1904058]; protein homotetramerization [GO:0051289]; regulation of blood circulation [GO:1903522]; regulation of neuronal action potential [GO:0098908]; response to cold [GO:0009409]; response to hydrogen peroxide [GO:0042542]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; sensory perception of pain [GO:0019233]; thermoception [GO:0050955]; transmembrane transport [GO:0055085]; urinary bladder smooth muscle contraction [GO:0014832] GO:0005216; GO:0005245; GO:0005262; GO:0005886; GO:0006816; GO:0006874; GO:0007166; GO:0009409; GO:0009410; GO:0010033; GO:0014070; GO:0014832; GO:0015267; GO:0015278; GO:0016324; GO:0019233; GO:0030424; GO:0032421; GO:0034220; GO:0034605; GO:0035774; GO:0042542; GO:0042802; GO:0048265; GO:0050955; GO:0050966; GO:0050968; GO:0050974; GO:0051289; GO:0055085; GO:0070301; GO:0070417; GO:0070588; GO:0071244; GO:0071310; GO:0071313; GO:0097553; GO:0097604; GO:0098908; GO:1903522; GO:1903793; GO:1904058; GO:1990760 46047 XM_044327422.1 0 0 23 0 15 P50130 9.4e-38 D(1A) dopamine receptor (Dopamine D1 receptor) Sus scrofa (Pig) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; vasodilation [GO:0042311] GO:0004930; GO:0004952; GO:0005789; GO:0005886; GO:0007189; GO:0042311; GO:0043197 46048 XM_044306922.1 2 1 2 5 801 Q7MF12 1.03e-42 Oxygen-dependent choline dehydrogenase (CDH) (CHD) (EC 1.1.99.1) (Betaine aldehyde dehydrogenase) (BADH) (EC 1.2.1.8) Vibrio vulnificus (strain YJ016) glycine betaine biosynthetic process from choline [GO:0019285] GO:0008802; GO:0008812; GO:0019285; GO:0050660 46049 XR_006394303.1 160 46 3 29 32 NA NA NA NA NA NA 46050 XM_029338715.2 32 0 0 7 15 NA NA NA NA NA NA 46051 XM_029346753.2 344 479 111 428 134 NA NA NA NA NA NA 46052 XM_044323670.1 18 0 0 0 0 P04323 2.19e-60 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 46053 XM_029324257.2 299 75 0 74 292 Q6NU40 0 Chromosome transmission fidelity protein 18 homolog Xenopus laevis (African clawed frog) cell cycle [GO:0007049]; DNA replication [GO:0006260] GO:0003677; GO:0003689; GO:0005524; GO:0005634; GO:0005663; GO:0006260; GO:0007049; GO:0016887 46054 XM_029336030.2 535 1449 203 408 271 E3SCZ8 3.02e-37 Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) Cavia porcellus (Guinea pig) apoptotic process [GO:0006915]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; meiosis I [GO:0007127]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of apoptotic process [GO:0043066]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of peptidase activity [GO:0010466]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; regulation of mitotic cell cycle [GO:0007346]; regulation of type B pancreatic cell proliferation [GO:0061469]; sensory perception of sound [GO:0007605] GO:0000226; GO:0000775; GO:0000776; GO:0004869; GO:0005634; GO:0005737; GO:0005874; GO:0006915; GO:0007059; GO:0007127; GO:0007346; GO:0007605; GO:0010466; GO:0030496; GO:0043066; GO:0043524; GO:0046872; GO:0051233; GO:0051301; GO:0061178; GO:0061469 46055 XM_044323331.1 245 133 74 312 67 Q6BZW3 3.14e-25 Protein BTN1 Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica) L-arginine transmembrane transport [GO:1903826]; lysine transport [GO:0015819]; regulation of intracellular pH [GO:0051453] GO:0000324; GO:0005773; GO:0005774; GO:0015819; GO:0022857; GO:0051453; GO:1903826 46056 XM_029351182.2 338 330 288 466 330 G5E8P0 1.06e-130 Gamma-tubulin complex component 6 (GCP-6) Mus musculus (Mouse) cytoplasmic microtubule organization [GO:0031122]; meiotic cell cycle [GO:0051321]; microtubule nucleation [GO:0007020]; mitotic cell cycle [GO:0000278]; spindle assembly [GO:0051225] GO:0000278; GO:0000922; GO:0000923; GO:0000930; GO:0000931; GO:0005813; GO:0005829; GO:0005874; GO:0007020; GO:0008017; GO:0008275; GO:0031122; GO:0043015; GO:0051225; GO:0051321 46057 XM_029351182.2 338 330 288 466 330 G5E8P0 2.58e-106 Gamma-tubulin complex component 6 (GCP-6) Mus musculus (Mouse) cytoplasmic microtubule organization [GO:0031122]; meiotic cell cycle [GO:0051321]; microtubule nucleation [GO:0007020]; mitotic cell cycle [GO:0000278]; spindle assembly [GO:0051225] GO:0000278; GO:0000922; GO:0000923; GO:0000930; GO:0000931; GO:0005813; GO:0005829; GO:0005874; GO:0007020; GO:0008017; GO:0008275; GO:0031122; GO:0043015; GO:0051225; GO:0051321 46058 XM_044324115.1 5 0 13 21 8 NA NA NA NA NA NA 46059 XM_044306889.1 597 78 419 68 1046 NA NA NA NA NA NA 46060 XM_029338739.2 0 0 0 0 8 Q9BVH7 6.4e-24 Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 (EC 2.4.99.-) (GD1 alpha synthase) (GalNAc alpha-2,6-sialyltransferase V) (ST6GalNAc V) (ST6GalNAcV) (Sialyltransferase 7E) (SIAT7-E) Homo sapiens (Human) ganglioside biosynthetic process [GO:0001574]; glycosphingolipid biosynthetic process [GO:0006688]; oligosaccharide biosynthetic process [GO:0009312]; oligosaccharide metabolic process [GO:0009311]; protein glycosylation [GO:0006486] GO:0000139; GO:0001574; GO:0001665; GO:0006486; GO:0006688; GO:0008373; GO:0009311; GO:0009312 46061 XR_003823984.2 287 198 149 311 392 NA NA NA NA NA NA 46062 XR_003825945.2 19 6 57 3 76 NA NA NA NA NA NA 46063 XR_006393115.1 10 0 3 24 7 NA NA NA NA NA NA 46064 XM_044327058.1 88 87 94 140 94 NA NA NA NA NA NA 46065 XR_006393449.1 149 107 168 337 417 NA NA NA NA NA NA 46066 XM_029329342.2 81 92 82 181 247 Q5M7C8 4.54e-64 HORMA domain-containing protein 1 Xenopus laevis (African clawed frog) meiotic cell cycle [GO:0051321]; meiotic DNA double-strand break formation [GO:0042138]; meiotic recombination checkpoint signaling [GO:0051598]; meiotic sister chromatid cohesion [GO:0051177]; oogenesis [GO:0048477]; regulation of homologous chromosome segregation [GO:0060629]; spermatogenesis [GO:0007283]; synaptonemal complex assembly [GO:0007130] GO:0005634; GO:0005694; GO:0007130; GO:0007283; GO:0042138; GO:0048477; GO:0051177; GO:0051321; GO:0051598; GO:0060629 46067 XM_029330495.2 222 229 86 260 407 P07902 2.41e-143 Galactose-1-phosphate uridylyltransferase (Gal-1-P uridylyltransferase) (EC 2.7.7.12) (UDP-glucose--hexose-1-phosphate uridylyltransferase) Homo sapiens (Human) galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]; UDP-glucose catabolic process [GO:0006258]; UDP-glucose metabolic process [GO:0006011] GO:0005737; GO:0005794; GO:0005829; GO:0006011; GO:0006012; GO:0006258; GO:0008108; GO:0008270; GO:0019388; GO:0033499 46068 XR_006394136.1 41 2 25 5 151 NA NA NA NA NA NA 46069 XM_044312774.1 302 789 1322 866 347 P35604 3.11e-86 Coatomer subunit zeta-1 (Zeta-1-coat protein) (Zeta-1 COP) Bos taurus (Bovine) intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; toxin transport [GO:1901998] GO:0000139; GO:0006886; GO:0006890; GO:0006891; GO:0030126; GO:1901998 46070 XM_044313512.1 36 15 13 30 8 P32929 0 Cystathionine gamma-lyase (CGL) (CSE) (EC 4.4.1.1) (Cysteine desulfhydrase) (Cysteine-protein sulfhydrase) (Gamma-cystathionase) (Homocysteine desulfhydrase) (EC 4.4.1.2) Homo sapiens (Human) cellular response to leukemia inhibitory factor [GO:1990830]; cysteine biosynthetic process [GO:0019344]; cysteine biosynthetic process via cystathionine [GO:0019343]; cysteine metabolic process [GO:0006534]; endoplasmic reticulum unfolded protein response [GO:0030968]; hydrogen sulfide biosynthetic process [GO:0070814]; lipid metabolic process [GO:0006629]; negative regulation of apoptotic signaling pathway [GO:2001234]; positive regulation of aortic smooth muscle cell differentiation [GO:1904831]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein homotetramerization [GO:0051289]; protein sulfhydration [GO:0044524]; protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine [GO:0018272]; transsulfuration [GO:0019346] GO:0004123; GO:0005516; GO:0005737; GO:0005829; GO:0006534; GO:0006629; GO:0016846; GO:0018272; GO:0019343; GO:0019344; GO:0019346; GO:0030170; GO:0030968; GO:0042802; GO:0043123; GO:0044524; GO:0044540; GO:0047982; GO:0051092; GO:0051289; GO:0070062; GO:0070814; GO:0080146; GO:0098606; GO:1904831; GO:1990830; GO:2001234 46071 XM_029348951.2 1303 775 1430 1901 1486 NA NA NA NA NA NA 46072 XM_029336738.2 231 0 192 55 119 Q5BK60 1.88e-26 Kelch-like protein 38 Rattus norvegicus (Rat) NA NA 46073 XM_044316959.1 6 0 0 0 7 NA NA NA NA NA NA 46074 XM_029349452.2 0 0 0 4 15 P54833 2.37e-21 Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor) Canis lupus familiaris (Dog) (Canis familiaris) activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; desensitization of G protein-coupled receptor signaling pathway by arrestin [GO:0002032]; negative regulation of smooth muscle contraction [GO:0045986]; norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0002025]; positive regulation of autophagosome maturation [GO:1901098]; positive regulation of lipophagy [GO:1904504]; positive regulation of MAPK cascade [GO:0043410]; receptor-mediated endocytosis [GO:0006898] GO:0002025; GO:0002032; GO:0004930; GO:0004941; GO:0005769; GO:0005794; GO:0005886; GO:0006898; GO:0007190; GO:0042803; GO:0043235; GO:0043410; GO:0045986; GO:0051380; GO:0071880; GO:1901098; GO:1904504 46075 XM_044320836.1 0 4 6 0 1 NA NA NA NA NA NA 46076 XM_029334614.2 144 0 0 147 0 Q8TE60 2.55e-130 A disintegrin and metalloproteinase with thrombospondin motifs 18 (ADAM-TS 18) (ADAM-TS18) (ADAMTS-18) (EC 3.4.24.-) Homo sapiens (Human) extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; negative regulation of platelet aggregation [GO:0090331]; proteolysis [GO:0006508] GO:0001654; GO:0004222; GO:0005576; GO:0006508; GO:0030198; GO:0031012; GO:0046872; GO:0090331 46077 XM_029346173.2 101 99 93 62 143 Q0VFM0 4.58e-81 Zinc finger protein-like 1 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) vesicle-mediated transport [GO:0016192] GO:0005794; GO:0016020; GO:0016192; GO:0046872 46078 XM_029352437.2 1719 1781 1245 1709 1750 P48380 0 Transcription factor RFX3 (Regulatory factor X 3) Homo sapiens (Human) cell maturation [GO:0048469]; cilium assembly [GO:0060271]; cilium-dependent cell motility [GO:0060285]; endocrine pancreas development [GO:0031018]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type B pancreatic cell development [GO:2000078]; regulation of DNA-templated transcription [GO:0006355]; regulation of insulin secretion [GO:0050796]; regulation of transcription by RNA polymerase II [GO:0006357]; type B pancreatic cell maturation [GO:0072560] GO:0000785; GO:0000976; GO:0000978; GO:0000981; GO:0003677; GO:0003700; GO:0005576; GO:0005634; GO:0005667; GO:0006355; GO:0006357; GO:0031018; GO:0045892; GO:0045893; GO:0045944; GO:0048469; GO:0050796; GO:0060271; GO:0060285; GO:0060287; GO:0072560; GO:1990837; GO:2000078 46079 XM_029332725.2 0 5 4 18 5 A7S4N4 5.67e-89 Probable serine incorporator Nematostella vectensis (Starlet sea anemone) phospholipid biosynthetic process [GO:0008654] GO:0005789; GO:0008654; GO:0016020 46080 XR_006396166.1 1948 1507 689 2487 1951 NA NA NA NA NA NA 46081 XM_044312494.1 580 446 136 73 269 NA NA NA NA NA NA 46082 XM_044318141.1 336 352 252 443 581 P33610 7.83e-176 DNA primase large subunit (DNA primase 58 kDa subunit) (p58) Mus musculus (Mouse) DNA replication initiation [GO:0006270]; DNA replication, synthesis of RNA primer [GO:0006269]; positive regulation of DNA primase activity [GO:1903934] GO:0003677; GO:0005658; GO:0006269; GO:0006270; GO:0046872; GO:0051539; GO:0071667; GO:1903934 46083 XM_029336580.2 209 195 177 336 422 Q8BXK8 4.86e-118 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 (AGAP-1) (Centaurin-gamma-2) (Cnt-g2) Mus musculus (Mouse) activation of GTPase activity [GO:0090630]; protein transport [GO:0015031] GO:0003924; GO:0005096; GO:0005525; GO:0005543; GO:0005829; GO:0015031; GO:0046872; GO:0090630 46084 XM_029336580.2 209 195 177 336 422 Q8BXK8 9.47e-49 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 (AGAP-1) (Centaurin-gamma-2) (Cnt-g2) Mus musculus (Mouse) activation of GTPase activity [GO:0090630]; protein transport [GO:0015031] GO:0003924; GO:0005096; GO:0005525; GO:0005543; GO:0005829; GO:0015031; GO:0046872; GO:0090630 46085 XR_003827933.2 379 259 0 55 0 Q9R1S3 4.37e-28 GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N) Mus musculus (Mouse) GPI anchor biosynthetic process [GO:0006506] GO:0005789; GO:0005829; GO:0005886; GO:0006506; GO:0016780; GO:0051377 46086 XR_003827933.2 379 259 0 55 0 Q9R1S3 4.37e-28 GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N) Mus musculus (Mouse) GPI anchor biosynthetic process [GO:0006506] GO:0005789; GO:0005829; GO:0005886; GO:0006506; GO:0016780; GO:0051377 46087 XM_044319838.1 0 0 236 231 429 Q6YP21 9.29e-155 Kynurenine--oxoglutarate transaminase 3 (EC 2.6.1.7) (Cysteine-S-conjugate beta-lyase 2) (EC 4.4.1.13) (Kynurenine aminotransferase 3) (Kynurenine aminotransferase III) (KATIII) (Kynurenine--glyoxylate transaminase) (EC 2.6.1.63) (Kynurenine--oxoglutarate transaminase III) Homo sapiens (Human) 2-oxoglutarate metabolic process [GO:0006103]; amino acid metabolic process [GO:0006520]; biosynthetic process [GO:0009058]; kynurenine metabolic process [GO:0070189]; L-kynurenine catabolic process [GO:0097053] GO:0003723; GO:0005737; GO:0005739; GO:0006103; GO:0006520; GO:0009058; GO:0016212; GO:0030170; GO:0042803; GO:0047315; GO:0047804; GO:0070189; GO:0097053 46088 XM_044314146.1 513 355 452 291 605 NA NA NA NA NA NA 46089 XM_029332737.2 157 86 68 50 147 O75031 3.14e-67 Heat shock factor 2-binding protein Homo sapiens (Human) double-strand break repair involved in meiotic recombination [GO:1990918]; female meiosis I [GO:0007144]; male meiosis I [GO:0007141]; spermatogenesis [GO:0007283]; transcription by RNA polymerase II [GO:0006366] GO:0005694; GO:0005829; GO:0006366; GO:0007141; GO:0007144; GO:0007283; GO:1990918 46090 XM_044310141.1 36 0 2 18 24 Q3UQ28 3.63e-29 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 46091 XM_044310141.1 36 0 2 18 24 Q3UQ28 1.07e-23 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 46092 XM_044314990.1 6 8 27 9 210 NA NA NA NA NA NA 46093 XM_029340217.2 135 0 76 83 0 NA NA NA NA NA NA 46094 XR_003823823.2 64 6 31 32 24 NA NA NA NA NA NA 46095 XR_006397735.1 117 113 63 95 93 NA NA NA NA NA NA 46096 XM_029324042.2 50 4 9 26 51 Q6DJ06 8.46e-37 LIM domain transcription factor LMO4.2 (LIM domain only protein 4.2) (LMO-4.2) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell differentiation [GO:0030154]; gastrulation [GO:0007369]; mesoderm development [GO:0007498]; negative regulation of neuron differentiation [GO:0045665]; nervous system development [GO:0007399]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0003712; GO:0007369; GO:0007399; GO:0007498; GO:0030154; GO:0045665; GO:0045944; GO:0046872 46097 XM_029354872.2 529 22 262 414 524 NA NA NA NA NA NA 46098 XM_029334402.2 33 3 21 20 12 NA NA NA NA NA NA 46099 XR_006391987.1 14 9 7 17 34 NA NA NA NA NA NA 46100 XM_029335883.2 11424 17639 9545 13237 6375 NA NA NA NA NA NA 46101 XM_044324856.1 2266 1512 1083 1995 2080 Q9BXJ9 0 N-alpha-acetyltransferase 15, NatA auxiliary subunit (Gastric cancer antigen Ga19) (N-terminal acetyltransferase) (NMDA receptor-regulated protein 1) (Protein tubedown-1) (Tbdn100) Homo sapiens (Human) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; N-terminal peptidyl-methionine acetylation [GO:0017196]; N-terminal protein amino acid acetylation [GO:0006474]; negative regulation of apoptotic process [GO:0043066]; positive regulation of DNA-templated transcription [GO:0045893]; protein stabilization [GO:0050821] GO:0001525; GO:0003723; GO:0005634; GO:0005667; GO:0005737; GO:0005829; GO:0006474; GO:0016020; GO:0016604; GO:0017196; GO:0030154; GO:0031415; GO:0043022; GO:0043066; GO:0043231; GO:0045893; GO:0050821 46102 XR_006391635.1 5 53 0 10 6 NA NA NA NA NA NA 46103 XM_044326136.1 0 18 0 10 4 NA NA NA NA NA NA 46104 XM_044307264.1 0 0 15 0 0 NA NA NA NA NA NA 46105 XR_006397859.1 41 14 46 35 26 NA NA NA NA NA NA 46106 XM_044314423.1 43 10 6 20 18 Q96AY4 1.91e-61 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 46107 XM_044314423.1 43 10 6 20 18 Q96AY4 2.21e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 46108 XM_044314423.1 43 10 6 20 18 Q96AY4 1.64e-55 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 46109 XM_044314423.1 43 10 6 20 18 Q96AY4 2.42e-53 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 46110 XM_044314423.1 43 10 6 20 18 Q96AY4 6.15e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 46111 XM_044314423.1 43 10 6 20 18 Q96AY4 5.77e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 46112 XM_029336332.2 4043 4007 3081 3350 3075 P61212 2.23e-101 ADP-ribosylation factor-like protein 1 Rattus norvegicus (Rat) activation of phospholipase D activity [GO:0031584]; Golgi organization [GO:0007030]; Golgi vesicle transport [GO:0048193]; intracellular protein transport [GO:0006886]; protein localization to Golgi apparatus [GO:0034067]; retrograde transport, endosome to Golgi [GO:0042147]; toxin metabolic process [GO:0009404]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0003924; GO:0005525; GO:0005737; GO:0005794; GO:0005802; GO:0005829; GO:0006886; GO:0007030; GO:0008047; GO:0009404; GO:0016192; GO:0019904; GO:0031584; GO:0034067; GO:0042147; GO:0046872; GO:0048193 46113 XM_029336609.2 1 24 0 29 2 NA NA NA NA NA NA 46114 XM_044309579.1 70 5 68 10 194 NA NA NA NA NA NA 46115 XM_029348492.2 25 20 8 7 49 NA NA NA NA NA NA 46116 XM_029334722.2 1955 3399 812 1520 1911 P62997 5.38e-43 Transformer-2 protein homolog beta (TRA-2 beta) (TRA2-beta) (RA301) (Splicing factor, arginine/serine-rich 10) (Transformer-2 protein homolog B) Rattus norvegicus (Rat) cellular response to glucose stimulus [GO:0071333]; cerebral cortex regionalization [GO:0021796]; embryonic brain development [GO:1990403]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of RNA splicing [GO:0043484]; response to reactive oxygen species [GO:0000302] GO:0000302; GO:0000381; GO:0000398; GO:0001673; GO:0003723; GO:0003729; GO:0005634; GO:0005637; GO:0005681; GO:0019904; GO:0021796; GO:0032991; GO:0036002; GO:0042802; GO:0043484; GO:0048026; GO:0048471; GO:0071333; GO:1990403 46117 XM_029339077.2 21 0 0 71 154 Q8N653 1.09e-24 Leucine-zipper-like transcriptional regulator 1 (LZTR-1) Homo sapiens (Human) negative regulation of Ras protein signal transduction [GO:0046580]; protein ubiquitination [GO:0016567] GO:0005794; GO:0012505; GO:0016567; GO:0031267; GO:0031463; GO:0046580; GO:0055038 46118 XM_044329103.1 6 0 0 0 13 NA NA NA NA NA NA 46119 XR_006395337.1 22 0 14 0 53 NA NA NA NA NA NA 46120 XM_029345710.2 38 0 89 23 14 NA NA NA NA NA NA 46121 XM_044318618.1 189 126 146 45 562 NA NA NA NA NA NA 46122 XM_029345432.2 0 0 0 0 16 NA NA NA NA NA NA 46123 XM_044327924.1 0 473 0 0 275 NA NA NA NA NA NA 46124 XM_029354654.2 1508 741 708 1170 1347 P35573 0 Glycogen debranching enzyme (Glycogen debrancher) [Includes: 4-alpha-glucanotransferase (EC 2.4.1.25) (Oligo-1,4-1,4-glucantransferase); Amylo-alpha-1,6-glucosidase (Amylo-1,6-glucosidase) (EC 3.2.1.33) (Dextrin 6-alpha-D-glucosidase)] Homo sapiens (Human) glycogen biosynthetic process [GO:0005978]; glycogen catabolic process [GO:0005980]; response to glucocorticoid [GO:0051384]; response to nutrient [GO:0007584] GO:0004133; GO:0004134; GO:0004135; GO:0005576; GO:0005634; GO:0005737; GO:0005829; GO:0005978; GO:0005980; GO:0007584; GO:0016234; GO:0016529; GO:0030247; GO:0031593; GO:0034774; GO:0043033; GO:0051384; GO:0102500; GO:1904813 46125 XM_044307651.1 0 0 116 0 10 Q03146 1.75e-99 Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (Protein-tyrosine kinase MPK-6) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a) Mus musculus (Mouse) axon development [GO:0061564]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell population proliferation [GO:0008283]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; ear development [GO:0043583]; embryo implantation [GO:0007566]; lactation [GO:0007595]; mammary gland alveolus development [GO:0060749]; negative regulation of cell population proliferation [GO:0008285]; neuron projection extension [GO:1990138]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of kinase activity [GO:0033674]; protein autophosphorylation [GO:0046777]; regulation of cell growth [GO:0001558]; regulation of cell-matrix adhesion [GO:0001952]; regulation of extracellular matrix disassembly [GO:0010715]; smooth muscle cell migration [GO:0014909]; smooth muscle cell-matrix adhesion [GO:0061302]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing, spreading of cells [GO:0044319] GO:0001558; GO:0001952; GO:0004714; GO:0005518; GO:0005524; GO:0005737; GO:0005886; GO:0005903; GO:0007169; GO:0007566; GO:0007595; GO:0008283; GO:0008285; GO:0010715; GO:0014909; GO:0016323; GO:0018108; GO:0033674; GO:0038062; GO:0038063; GO:0038083; GO:0043235; GO:0043583; GO:0044319; GO:0046777; GO:0046872; GO:0060444; GO:0060749; GO:0061302; GO:0061564; GO:1990138 46126 XM_044307651.1 0 0 116 0 10 Q03146 1.25e-24 Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (Protein-tyrosine kinase MPK-6) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a) Mus musculus (Mouse) axon development [GO:0061564]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell population proliferation [GO:0008283]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; ear development [GO:0043583]; embryo implantation [GO:0007566]; lactation [GO:0007595]; mammary gland alveolus development [GO:0060749]; negative regulation of cell population proliferation [GO:0008285]; neuron projection extension [GO:1990138]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of kinase activity [GO:0033674]; protein autophosphorylation [GO:0046777]; regulation of cell growth [GO:0001558]; regulation of cell-matrix adhesion [GO:0001952]; regulation of extracellular matrix disassembly [GO:0010715]; smooth muscle cell migration [GO:0014909]; smooth muscle cell-matrix adhesion [GO:0061302]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing, spreading of cells [GO:0044319] GO:0001558; GO:0001952; GO:0004714; GO:0005518; GO:0005524; GO:0005737; GO:0005886; GO:0005903; GO:0007169; GO:0007566; GO:0007595; GO:0008283; GO:0008285; GO:0010715; GO:0014909; GO:0016323; GO:0018108; GO:0033674; GO:0038062; GO:0038063; GO:0038083; GO:0043235; GO:0043583; GO:0044319; GO:0046777; GO:0046872; GO:0060444; GO:0060749; GO:0061302; GO:0061564; GO:1990138 46127 XM_029328968.2 558 293 140 354 281 NA NA NA NA NA NA 46128 XM_044320136.1 14 1 0 4 0 NA NA NA NA NA NA 46129 XM_044309277.1 591 198 1374 5159 3377 P20825 3.84e-96 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 46130 XM_044324538.1 5 1 0 20 34 NA NA NA NA NA NA 46131 XR_006394175.1 503 144 169 166 260 NA NA NA NA NA NA 46132 XM_029337794.2 102 289 0 872 693 B3EWY9 5.91e-28 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 46133 XM_029337794.2 102 289 0 872 693 B3EWY9 8.28e-24 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 46134 XM_029335822.2 59 24 40 19 74 Q8BPM0 2.21e-31 Disheveled-associated activator of morphogenesis 1 Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; Wnt signaling pathway [GO:0016055] GO:0001725; GO:0003779; GO:0005829; GO:0005886; GO:0016055; GO:0030036; GO:0031267; GO:0031514; GO:0036064; GO:0042802 46135 XM_029356314.2 42 39 0 7 28 Q6DFB7 1.51e-55 Centrosomal protein POC5 (Protein of centriole 5) Xenopus laevis (African clawed frog) cell cycle [GO:0007049] GO:0005737; GO:0005814; GO:0007049 46136 XM_044322006.1 390 0 0 74 0 Q6PDQ2 0 Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC 3.6.4.12) Mus musculus (Mouse) chromatin remodeling [GO:0006338]; histone deacetylation [GO:0016575]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of cell fate specification [GO:0042659]; regulation of stem cell differentiation [GO:2000736]; regulation of synapse assembly [GO:0051963]; terminal button organization [GO:0072553] GO:0000122; GO:0000781; GO:0000785; GO:0001221; GO:0003677; GO:0003682; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0006338; GO:0010629; GO:0016575; GO:0016581; GO:0016887; GO:0032991; GO:0032993; GO:0042393; GO:0042659; GO:0042826; GO:0045892; GO:0045893; GO:0046872; GO:0051963; GO:0061629; GO:0072553; GO:0090575; GO:0140297; GO:0140658; GO:0150048; GO:2000736 46137 XM_044322006.1 390 0 0 74 0 Q6PDQ2 2e-59 Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC 3.6.4.12) Mus musculus (Mouse) chromatin remodeling [GO:0006338]; histone deacetylation [GO:0016575]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of cell fate specification [GO:0042659]; regulation of stem cell differentiation [GO:2000736]; regulation of synapse assembly [GO:0051963]; terminal button organization [GO:0072553] GO:0000122; GO:0000781; GO:0000785; GO:0001221; GO:0003677; GO:0003682; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0006338; GO:0010629; GO:0016575; GO:0016581; GO:0016887; GO:0032991; GO:0032993; GO:0042393; GO:0042659; GO:0042826; GO:0045892; GO:0045893; GO:0046872; GO:0051963; GO:0061629; GO:0072553; GO:0090575; GO:0140297; GO:0140658; GO:0150048; GO:2000736 46138 XM_044327083.1 0 73 0 18 15 NA NA NA NA NA NA 46139 XM_044313506.1 0 16 2 1 18 NA NA NA NA NA NA 46140 XM_044319983.1 0 2 0 12 3 NA NA NA NA NA NA 46141 XM_029334558.2 0 0 36 0 0 P46250 3.37e-29 SEC14 cytosolic factor (Phosphatidylinositol/phosphatidylcholine transfer protein) (PI/PC TP) Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) ascospore formation [GO:0030437]; CDP-choline pathway [GO:0006657]; Golgi to plasma membrane protein transport [GO:0043001]; Golgi to vacuole transport [GO:0006896]; Golgi vesicle budding [GO:0048194]; negative regulation of phosphatidylcholine biosynthetic process [GO:2001246]; negative regulation of phosphatidylglycerol biosynthetic process [GO:1901352]; phosphatidylinositol metabolic process [GO:0046488]; post-Golgi vesicle-mediated transport [GO:0006892] GO:0000139; GO:0005794; GO:0005829; GO:0006657; GO:0006892; GO:0006896; GO:0008525; GO:0008526; GO:0030437; GO:0043001; GO:0046488; GO:0048194; GO:1901352; GO:2001246 46142 XM_029346917.2 266 104 114 298 137 Q6GMF8 4.07e-155 Inactive rhomboid protein 1 (iRhom1) (Rhomboid family member 1) Danio rerio (Zebrafish) (Brachydanio rerio) cell migration [GO:0016477]; cell population proliferation [GO:0008283]; negative regulation of protein secretion [GO:0050709]; protein transport [GO:0015031]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of protein secretion [GO:0050708] GO:0000139; GO:0005789; GO:0008283; GO:0015031; GO:0016477; GO:0019838; GO:0042058; GO:0050708; GO:0050709; GO:0061136 46143 XM_029335235.2 315 263 242 181 277 NA NA NA NA NA NA 46144 XM_044309844.1 0 0 0 0 6 NA NA NA NA NA NA 46145 XM_044307872.1 673 363 489 783 1113 Q8BKE9 7.99e-156 Intraflagellar transport protein 74 homolog (Capillary morphogenesis gene 1 protein) (CMG-1) (Coiled-coil domain-containing protein 2) Mus musculus (Mouse) cilium assembly [GO:0060271]; determination of left/right symmetry [GO:0007368]; epidermis development [GO:0008544]; heart development [GO:0007507]; intraciliary anterograde transport [GO:0035720]; intraciliary transport [GO:0042073]; intraciliary transport involved in cilium assembly [GO:0035735]; keratinocyte development [GO:0003334]; keratinocyte proliferation [GO:0043616]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of keratinocyte proliferation [GO:0010839]; non-motile cilium assembly [GO:1905515]; Notch signaling pathway [GO:0007219]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0001669; GO:0003334; GO:0003682; GO:0005634; GO:0005813; GO:0005929; GO:0007219; GO:0007368; GO:0007507; GO:0008544; GO:0010839; GO:0030992; GO:0031514; GO:0033630; GO:0035720; GO:0035735; GO:0042073; GO:0043616; GO:0045944; GO:0048487; GO:0050680; GO:0060271; GO:1905515 46146 XM_044319346.1 4 7 14 0 6 NA NA NA NA NA NA 46147 XM_044310104.1 0 47 49 25 0 NA NA NA NA NA NA 46148 XM_044317477.1 230 269 193 116 184 NA NA NA NA NA NA 46149 XR_006392901.1 41 2 25 5 151 NA NA NA NA NA NA 46150 XM_029348022.2 938 485 263 506 404 NA NA NA NA NA NA 46151 XR_006396759.1 0 0 97 6 419 NA NA NA NA NA NA 46152 XM_029353040.2 2761 3116 1882 2340 1756 Q962X9 2.94e-93 Protein BUD31 homolog (Protein G10 homolog) Branchiostoma belcheri (Amphioxus) NA GO:0005634 46153 XM_029356282.2 29 0 41 29 127 Q58A42 4.82e-62 Protein DD3-3 Dictyostelium discoideum (Social amoeba) NA GO:0016020 46154 XM_029356099.2 30 0 0 45 11 NA NA NA NA NA NA 46155 XM_044327152.1 587 662 834 99 246 B8VIW9 0 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 46156 XM_029352164.2 18 2 30 10 36 Q804X9 1.53e-38 Melanopsin-A (Opsin-4A) Gadus morhua (Atlantic cod) phototransduction [GO:0007602]; visual perception [GO:0007601] GO:0004930; GO:0005886; GO:0007601; GO:0007602; GO:0009881 46157 XM_029334471.2 58 0 0 0 146 Q6DKN2 9.34e-32 Homeobox protein OTX2-B (xOTX2-B) (Orthodenticle 2-B) (Orthodenticle-A-like protein B) Xenopus laevis (African clawed frog) NA GO:0000981; GO:0003677; GO:0005634 46158 XM_029336828.2 0 0 0 165 50 NA NA NA NA NA NA 46159 XM_044322328.1 0 0 8 0 1 Q09575 1.25e-38 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 46160 XM_044319079.1 12 10 5 15 4 NA NA NA NA NA NA 46161 XR_006395157.1 37 16 11 64 70 NA NA NA NA NA NA 46162 XR_003827185.2 458 510 250 697 226 NA NA NA NA NA NA 46163 XM_044322652.1 53 20 33 67 38 NA NA NA NA NA NA 46164 XM_029337037.2 20 0 120 27 130 Q8HYZ1 5.49e-100 Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2) Mustela putorius furo (European domestic ferret) (Mustela furo) cardiac muscle cell action potential [GO:0086001]; cellular response to hypoxia [GO:0071456]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005250; GO:0005886; GO:0005901; GO:0008076; GO:0030315; GO:0032809; GO:0034765; GO:0042383; GO:0043197; GO:0043204; GO:0044853; GO:0045211; GO:0046872; GO:0051260; GO:0070161; GO:0071456; GO:0071805; GO:0086001 46165 XM_044326688.1 422 329 239 246 314 NA NA NA NA NA NA 46166 XM_044312201.1 84 6 0 44 24 NA NA NA NA NA NA 46167 XM_044326307.1 1131 1086 1182 979 1031 Q9DC53 0 Copine-8 (Copine VIII) Mus musculus (Mouse) cellular response to calcium ion [GO:0071277] GO:0005544; GO:0005886; GO:0046872; GO:0071277 46168 XM_044314259.1 4 1 7 0 0 Q8BR76 9.66e-27 Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67) Mus musculus (Mouse) branching morphogenesis of an epithelial tube [GO:0048754]; cilium assembly [GO:0060271]; determination of left/right symmetry [GO:0007368]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; head development [GO:0060322]; heart development [GO:0007507]; kidney development [GO:0001822]; negative regulation of centrosome duplication [GO:0010826]; non-canonical Wnt signaling pathway [GO:0035567]; photoreceptor cell outer segment organization [GO:0035845]; positive regulation of ERAD pathway [GO:1904294]; positive regulation of non-motile cilium assembly [GO:1902857]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0001822; GO:0005789; GO:0005813; GO:0005886; GO:0005929; GO:0005930; GO:0007368; GO:0007507; GO:0010826; GO:0030433; GO:0030659; GO:0031005; GO:0035567; GO:0035845; GO:0035869; GO:0036038; GO:0048754; GO:0051082; GO:0051787; GO:0060170; GO:0060271; GO:0060322; GO:0060441; GO:1902857; GO:1904294 46169 XR_006394932.1 256 1 291 3 369 NA NA NA NA NA NA 46170 XM_044316389.1 38 37 76 1 23 Q9DDT2 9.28e-23 Phosphoinositide 3-kinase adapter protein 1 (B-cell adapter for phosphoinositide 3-kinase) (B-cell phosphoinositide 3-kinase adapter protein 1) Gallus gallus (Chicken) cellular response to insulin stimulus [GO:0032869]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; regulation of inflammatory response [GO:0050727]; regulation of kinase activity [GO:0043549]; regulation of phosphorylation [GO:0042325]; toll-like receptor 2 signaling pathway [GO:0034134]; toll-like receptor 4 signaling pathway [GO:0034142]; toll-like receptor 7 signaling pathway [GO:0034154]; toll-like receptor 9 signaling pathway [GO:0034162]; TOR signaling [GO:0031929] GO:0005102; GO:0005829; GO:0005886; GO:0014068; GO:0016020; GO:0031929; GO:0032869; GO:0034134; GO:0034142; GO:0034154; GO:0034162; GO:0036312; GO:0042325; GO:0043549; GO:0050727 46171 XR_006391800.1 10 10 20 27 16 NA NA NA NA NA NA 46172 XR_006393678.1 26 0 0 0 11 NA NA NA NA NA NA 46173 XM_044328610.1 161 8 11 60 23 Q8CEE6 1.14e-115 PAS domain-containing serine/threonine-protein kinase (PAS-kinase) (PASKIN) (EC 2.7.11.1) Mus musculus (Mouse) energy homeostasis [GO:0097009]; intracellular signal transduction [GO:0035556]; negative regulation of glycogen biosynthetic process [GO:0045719]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of glucagon secretion [GO:0070092]; regulation of respiratory gaseous exchange [GO:0043576] GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006468; GO:0035091; GO:0035556; GO:0043576; GO:0045719; GO:0046777; GO:0070092; GO:0097009; GO:0106310 46174 XM_044328610.1 161 8 11 60 23 Q8CEE6 2.8e-63 PAS domain-containing serine/threonine-protein kinase (PAS-kinase) (PASKIN) (EC 2.7.11.1) Mus musculus (Mouse) energy homeostasis [GO:0097009]; intracellular signal transduction [GO:0035556]; negative regulation of glycogen biosynthetic process [GO:0045719]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of glucagon secretion [GO:0070092]; regulation of respiratory gaseous exchange [GO:0043576] GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006468; GO:0035091; GO:0035556; GO:0043576; GO:0045719; GO:0046777; GO:0070092; GO:0097009; GO:0106310 46175 XM_044318367.1 356 325 111 255 350 NA NA NA NA NA NA 46176 XR_003826172.2 2 0 0 12 5 NA NA NA NA NA NA 46177 XM_029346281.2 851 392 371 781 965 Q15678 2.89e-65 Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez) Homo sapiens (Human) lymphangiogenesis [GO:0001946]; negative regulation of cell population proliferation [GO:0008285]; protein dephosphorylation [GO:0006470]; regulation of protein export from nucleus [GO:0046825] GO:0001946; GO:0003712; GO:0004725; GO:0005634; GO:0005654; GO:0005737; GO:0005856; GO:0006470; GO:0008285; GO:0030971; GO:0046825 46178 XM_029346281.2 851 392 371 781 965 Q15678 1.64e-43 Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez) Homo sapiens (Human) lymphangiogenesis [GO:0001946]; negative regulation of cell population proliferation [GO:0008285]; protein dephosphorylation [GO:0006470]; regulation of protein export from nucleus [GO:0046825] GO:0001946; GO:0003712; GO:0004725; GO:0005634; GO:0005654; GO:0005737; GO:0005856; GO:0006470; GO:0008285; GO:0030971; GO:0046825 46179 XM_044328536.1 415 303 493 550 353 Q32PH0 1.27e-152 Trafficking protein particle complex subunit 9 (NIK- and IKBKB-binding protein) Bos taurus (Bovine) cell differentiation [GO:0030154] GO:0005783; GO:0005794; GO:0030154 46180 XM_044310772.1 385 419 154 423 233 NA NA NA NA NA NA 46181 XR_006391654.1 0 0 25 0 45 Q570Y9 8.58e-43 DEP domain-containing mTOR-interacting protein (DEP domain-containing protein 6) Mus musculus (Mouse) intracellular signal transduction [GO:0035556]; negative regulation of cell size [GO:0045792]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of TOR signaling [GO:0032007]; negative regulation of TORC1 signaling [GO:1904262]; negative regulation of TORC2 signaling [GO:1903940]; regulation of extrinsic apoptotic signaling pathway [GO:2001236] GO:0006469; GO:0032007; GO:0035556; GO:0045792; GO:1903940; GO:1904262; GO:2001236 46182 XR_003827289.2 35 48 38 0 0 NA NA NA NA NA NA 46183 XM_029334970.2 15 11 36 12 137 P51476 3.4e-37 Pinopsin (Pineal gland-specific opsin) (P-opsin) (Pineal opsin) Columba livia (Rock dove) light absorption [GO:0016037]; phototransduction [GO:0007602]; visual perception [GO:0007601] GO:0004930; GO:0007601; GO:0007602; GO:0009881; GO:0016020; GO:0016037 46184 XM_044310165.1 21 32 17 18 9 NA NA NA NA NA NA 46185 XM_044328795.1 112 70 87 148 210 Q9CS74 3.28e-147 Protein ecdysoneless homolog Mus musculus (Mouse) fibroblast proliferation [GO:0048144]; mRNA processing [GO:0006397]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; RNA splicing [GO:0008380] GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006397; GO:0008380; GO:0035035; GO:0045944; GO:0048144; GO:2000045 46186 XM_029330400.2 264 197 49 168 0 NA NA NA NA NA NA 46187 XM_029347386.2 3992 3202 2312 3217 2720 Q6XPS3 6.59e-119 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (Lipid phosphatase TPIP) (TPTE and PTEN homologous inositol lipid phosphatase) Homo sapiens (Human) cell motility [GO:0048870]; dephosphorylation [GO:0016311]; negative regulation of cell population proliferation [GO:0008285]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; protein dephosphorylation [GO:0006470]; regulation of protein kinase B signaling [GO:0051896] GO:0000139; GO:0004725; GO:0005634; GO:0005737; GO:0005789; GO:0005829; GO:0005886; GO:0006470; GO:0006661; GO:0008285; GO:0014065; GO:0016311; GO:0016314; GO:0042995; GO:0046856; GO:0048870; GO:0051800; GO:0051896 46188 XM_029342237.2 2772 2313 1077 1607 993 NA NA NA NA NA NA 46189 XM_029354728.2 1512 1274 208 479 510 A0A2B4SES9 1.13e-74 NA NA NA NA 46190 XM_029335985.2 23 0 19 11 38 Q49SH1 3.92e-101 Sodium/potassium/calcium exchanger 5 (Na(+)/K(+)/Ca(2+)-exchange protein 5) (Protein golden) (Solute carrier family 24 member 5) Danio rerio (Zebrafish) (Brachydanio rerio) calcium ion transport [GO:0006816]; potassium ion transport [GO:0006813]; response to stimulus [GO:0050896]; sodium ion transport [GO:0006814] GO:0005794; GO:0006813; GO:0006814; GO:0006816; GO:0015293; GO:0015297; GO:0016020; GO:0042470; GO:0050896 46191 XM_044308789.1 417 460 253 427 542 P81900 3.6e-52 cAMP-dependent protein kinase type II regulatory subunit Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; behavioral response to cocaine [GO:0048148]; behavioral response to ethanol [GO:0048149]; cellular response to ethanol [GO:0071361]; circadian rhythm [GO:0007623]; locomotor rhythm [GO:0045475]; negative regulation of cAMP-dependent protein kinase activity [GO:2000480]; rhythmic behavior [GO:0007622] GO:0004862; GO:0005737; GO:0005886; GO:0005952; GO:0007411; GO:0007622; GO:0007623; GO:0030552; GO:0034236; GO:0045475; GO:0048148; GO:0048149; GO:0071361; GO:2000480 46192 XM_029342885.2 735 1393 231 1060 390 Q4R0J7 3.44e-44 D-arabinitol dehydrogenase 1 (EC 1.1.1.287) (NADP-dependent D-arabitol dehydrogenase) Uromyces fabae (Rust fungus) carbohydrate metabolic process [GO:0005975] GO:0005975; GO:0008270; GO:0033709; GO:0042995; GO:0052677 46193 XM_044328543.1 0 13 1 0 0 Q9C0B0 5.1e-142 RING finger protein unkempt homolog (Zinc finger CCCH domain-containing protein 5) Homo sapiens (Human) cell morphogenesis involved in neuron differentiation [GO:0048667]; in utero embryonic development [GO:0001701]; negative regulation of cytoplasmic translation [GO:2000766]; neuron migration [GO:0001764] GO:0001701; GO:0001764; GO:0003723; GO:0005737; GO:0005844; GO:0046872; GO:0048667; GO:1905538; GO:1990715; GO:2000766 46194 XM_044328543.1 0 13 1 0 0 Q9C0B0 8.97e-35 RING finger protein unkempt homolog (Zinc finger CCCH domain-containing protein 5) Homo sapiens (Human) cell morphogenesis involved in neuron differentiation [GO:0048667]; in utero embryonic development [GO:0001701]; negative regulation of cytoplasmic translation [GO:2000766]; neuron migration [GO:0001764] GO:0001701; GO:0001764; GO:0003723; GO:0005737; GO:0005844; GO:0046872; GO:0048667; GO:1905538; GO:1990715; GO:2000766 46195 XR_006392425.1 10 7 18 36 18 NA NA NA NA NA NA 46196 XM_044327007.1 0 0 1 0 9 NA NA NA NA NA NA 46197 XM_044311839.1 12 34 2 48 43 Q96AY4 9.56e-100 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 46198 XM_044311839.1 12 34 2 48 43 Q96AY4 1.79e-96 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 46199 XM_044311839.1 12 34 2 48 43 Q96AY4 7.18e-94 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 46200 XM_044311839.1 12 34 2 48 43 Q96AY4 9.62e-94 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 46201 XM_044311839.1 12 34 2 48 43 Q96AY4 6.82e-80 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 46202 XM_044311839.1 12 34 2 48 43 Q96AY4 2.33e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 46203 XM_044317049.1 0 1 0 337 0 Q96D71 1.14e-25 RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1) Homo sapiens (Human) endocytosis [GO:0006897]; endosomal transport [GO:0016197] GO:0005509; GO:0005829; GO:0005886; GO:0005905; GO:0006897; GO:0016197; GO:0017124 46204 XM_029345132.2 892 553 719 579 498 Q5PQ44 4.76e-125 Cilia- and flagella-associated protein 299 Xenopus laevis (African clawed frog) NA GO:0005634; GO:0005737 46205 XR_003825920.2 6 6 3 18 1 NA NA NA NA NA NA 46206 XM_029340722.2 372 586 197 337 732 Q3UZD5 8.19e-35 Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.361) (PR domain zinc finger protein 6) (PR domain-containing protein 6) (PR domain-containing protein in smooth muscle) Mus musculus (Mouse) chromatin organization [GO:0006325]; histone methylation [GO:0016571]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of smooth muscle cell differentiation [GO:0051151]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of gene expression [GO:0010468] GO:0000122; GO:0005634; GO:0006325; GO:0010468; GO:0016571; GO:0022008; GO:0042802; GO:0045892; GO:0046872; GO:0051151; GO:0140944 46207 XR_006392171.1 73 9 11 32 4 NA NA NA NA NA NA 46208 XM_029335192.2 1230 1090 723 672 684 Q9Y535 1.44e-81 DNA-directed RNA polymerase III subunit RPC8 (RNA polymerase III subunit C8) (DNA-directed RNA polymerase III subunit H) (RNA polymerase III subunit 22.9 kDa subunit) (RPC22.9) Homo sapiens (Human) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; nucleobase-containing compound metabolic process [GO:0006139]; transcription by RNA polymerase III [GO:0006383]; transcription initiation at RNA polymerase III promoter [GO:0006384] GO:0003677; GO:0003899; GO:0005654; GO:0005666; GO:0005813; GO:0005829; GO:0006139; GO:0006383; GO:0006384; GO:0043231; GO:0045087; GO:0051607 46209 XR_006395938.1 228 53 38 91 39 NA NA NA NA NA NA 46210 XM_044322809.1 613 604 7 1312 1587 Q13591 2.64e-70 Semaphorin-5A (Semaphorin-F) (Sema F) Homo sapiens (Human) axon extension [GO:0048675]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell-cell signaling [GO:0007267]; diencephalon development [GO:0021536]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of cell adhesion [GO:0007162]; negative regulation of endothelial cell apoptotic process [GO:2000352]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; positive chemotaxis [GO:0050918]; positive regulation of actin filament depolymerization [GO:0030836]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein kinase B signaling [GO:0051897]; semaphorin-plexin signaling pathway [GO:0071526]; signal clustering [GO:1990256] GO:0001755; GO:0001938; GO:0002043; GO:0005886; GO:0007155; GO:0007162; GO:0007267; GO:0007399; GO:0007411; GO:0007413; GO:0016020; GO:0021536; GO:0030215; GO:0030335; GO:0030836; GO:0035373; GO:0043395; GO:0045499; GO:0045545; GO:0045766; GO:0048675; GO:0048842; GO:0048843; GO:0050918; GO:0051897; GO:0060326; GO:0070062; GO:0071526; GO:0090263; GO:1990256; GO:2000352; GO:2001028 46211 XM_044318169.1 124 63 55 78 145 O70157 0 DNA topoisomerase 3-alpha (EC 5.6.2.1) (DNA topoisomerase III alpha) Mus musculus (Mouse) chromosome separation [GO:0051304]; DNA topological change [GO:0006265]; double-strand break repair via homologous recombination [GO:0000724]; mitochondrial DNA metabolic process [GO:0032042]; resolution of recombination intermediates [GO:0071139] GO:0000724; GO:0003697; GO:0003916; GO:0003917; GO:0005634; GO:0005654; GO:0005759; GO:0006265; GO:0008270; GO:0016605; GO:0031422; GO:0032042; GO:0051304; GO:0071139 46212 XR_006396540.1 21 20 19 207 48 NA NA NA NA NA NA 46213 XM_044308090.1 3 0 6 3 11 P11023 1.63e-67 Ras-related protein Rab-3A (SMG P25A) Bos taurus (Bovine) axonogenesis [GO:0007409]; calcium-ion regulated exocytosis [GO:0017156]; lung development [GO:0030324]; maintenance of presynaptic active zone structure [GO:0048790]; mitochondrion organization [GO:0007005]; neuromuscular synaptic transmission [GO:0007274]; post-embryonic development [GO:0009791]; protein localization to plasma membrane [GO:0072659]; protein secretion [GO:0009306]; regulation of exocytosis [GO:0017157]; regulation of synaptic vesicle fusion to presynaptic active zone membrane [GO:0031630]; respiratory system process [GO:0003016]; response to electrical stimulus [GO:0051602]; sensory perception of touch [GO:0050975]; synaptic vesicle exocytosis [GO:0016079]; synaptic vesicle maturation [GO:0016188]; vesicle docking involved in exocytosis [GO:0006904] GO:0003016; GO:0003924; GO:0005525; GO:0005764; GO:0005768; GO:0005829; GO:0005886; GO:0006904; GO:0007005; GO:0007274; GO:0007409; GO:0008021; GO:0009306; GO:0009791; GO:0016020; GO:0016079; GO:0016188; GO:0017156; GO:0017157; GO:0030324; GO:0030424; GO:0030672; GO:0031489; GO:0031630; GO:0043231; GO:0048786; GO:0048790; GO:0050975; GO:0051602; GO:0072659; GO:0098793; GO:0098794 46214 XM_044307496.1 79 31 30 69 26 NA NA NA NA NA NA 46215 XM_029347018.2 16 10 26 14 98 NA NA NA NA NA NA 46216 XM_044307697.1 536 313 180 425 544 NA NA NA NA NA NA 46217 XM_044310483.1 199 100 240 0 120 NA NA NA NA NA NA 46218 XM_044328412.1 374 445 91 437 252 Q4R4J0 6.45e-61 Rho GDP-dissociation inhibitor 1 (Rho GDI 1) (Rho-GDI alpha) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526] GO:0005094; GO:0005096; GO:0005737; GO:0007266; GO:0071526 46219 XM_044318349.1 96 25 3 4 57 O42957 1.71e-29 Ubiquitin-like-specific protease 1 (EC 3.4.22.-) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) protein desumoylation [GO:0016926]; protein processing [GO:0016485] GO:0005634; GO:0005635; GO:0005737; GO:0005829; GO:0016485; GO:0016926; GO:0016929; GO:0034399; GO:0070139 46220 XM_029344237.2 4 6 0 6 6 NA NA NA NA NA NA 46221 XR_003825452.2 96 85 36 129 62 NA NA NA NA NA NA 46222 XR_006391822.1 0 0 0 7 5 NA NA NA NA NA NA 46223 XM_029343795.2 197 64 131 604 605 NA NA NA NA NA NA 46224 XM_044316219.1 586 392 262 670 413 Q6IPM2 1.1e-31 IQ domain-containing protein E Homo sapiens (Human) limb morphogenesis [GO:0035108] GO:0005929; GO:0035108; GO:0060170 46225 XM_029330705.2 48 16 26 13 35 NA NA NA NA NA NA 46226 XM_044309123.1 377 93 116 120 45 Q9Z0W3 0 Nuclear pore complex protein Nup160 (160 kDa nucleoporin) (Gene trap locus 1-13 protein) (GTL-13) (Nucleoporin Nup160) Mus musculus (Mouse) mRNA export from nucleus [GO:0006406]; nephron development [GO:0072006]; nucleocytoplasmic transport [GO:0006913]; protein transport [GO:0015031] GO:0000776; GO:0005635; GO:0005643; GO:0006406; GO:0006913; GO:0015031; GO:0017056; GO:0031080; GO:0072006 46227 XM_029328681.2 130 0 0 0 92 NA NA NA NA NA NA 46228 XM_029350092.2 653 237 179 459 508 P56941 0 NPC intracellular cholesterol transporter 1 (Niemann-Pick C1 protein) Sus scrofa (Pig) bile acid metabolic process [GO:0008206]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; cholesterol transport [GO:0030301]; intestinal cholesterol absorption [GO:0030299]; intracellular cholesterol transport [GO:0032367]; lysosomal transport [GO:0007041]; negative regulation of TORC1 signaling [GO:1904262]; protein glycosylation [GO:0006486]; sterol transport [GO:0015918] GO:0005319; GO:0005576; GO:0005635; GO:0005764; GO:0005765; GO:0005783; GO:0005886; GO:0006486; GO:0007041; GO:0008203; GO:0008206; GO:0015485; GO:0015918; GO:0016020; GO:0030299; GO:0030301; GO:0031902; GO:0032367; GO:0032934; GO:0042632; GO:0048471; GO:1904262 46229 XR_003824926.2 14 0 18 4 14 NA NA NA NA NA NA 46230 XM_044325524.1 0 60 51 0 86 O15439 0 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 46231 XM_044320301.1 1091 656 659 1221 1154 Q27802 0 Cytoplasmic dynein 2 heavy chain 1 (Dynein heavy chain isotype 1B) Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla) cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] GO:0005524; GO:0005737; GO:0005874; GO:0005886; GO:0005929; GO:0007018; GO:0008569; GO:0030030; GO:0030286; GO:0045505; GO:0051959 46232 XM_044314060.1 16 38 1 8 61 NA NA NA NA NA NA 46233 XM_044322410.1 124 109 57 50 187 Q7SXM0 1.32e-147 Histone deacetylase 8 (HD8) (EC 3.5.1.98) (Protein deacetylase HDAC8) (EC 3.5.1.-) (Protein decrotonylase HDAC8) (EC 3.5.1.-) Danio rerio (Zebrafish) (Brachydanio rerio) central nervous system development [GO:0007417]; chromatin organization [GO:0006325]; histone deacetylation [GO:0016575]; neuron cellular homeostasis [GO:0070050]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000118; GO:0004407; GO:0005694; GO:0005737; GO:0006325; GO:0006357; GO:0007417; GO:0016575; GO:0046872; GO:0070050; GO:0160009 46234 XM_029333534.2 205 189 96 133 212 Q9WVF7 0 DNA polymerase epsilon catalytic subunit A (EC 2.7.7.7) (3'-5' exodeoxyribonuclease) (EC 3.1.11.-) (DNA polymerase II subunit A) Mus musculus (Mouse) base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; DNA replication proofreading [GO:0045004]; DNA synthesis involved in DNA repair [GO:0000731]; DNA-templated DNA replication [GO:0006261]; embryonic organ development [GO:0048568]; G1/S transition of mitotic cell cycle [GO:0000082]; leading strand elongation [GO:0006272]; mitotic cell cycle [GO:0000278]; nucleotide-excision repair, DNA gap filling [GO:0006297] GO:0000082; GO:0000166; GO:0000278; GO:0000731; GO:0003677; GO:0003682; GO:0003887; GO:0005634; GO:0005654; GO:0005886; GO:0006260; GO:0006261; GO:0006272; GO:0006287; GO:0006297; GO:0008270; GO:0008310; GO:0008622; GO:0045004; GO:0048568; GO:0051539; GO:0071897 46235 XM_029335616.2 884 719 586 1364 553 O43272 3.11e-161 Proline dehydrogenase 1, mitochondrial (EC 1.5.5.2) (Proline oxidase) (Proline oxidase 2) (p53-induced gene 6 protein) Homo sapiens (Human) 4-hydroxyproline catabolic process [GO:0019470]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; positive regulation of cell death [GO:0010942]; proline catabolic process [GO:0006562]; proline catabolic process to glutamate [GO:0010133]; proline metabolic process [GO:0006560] GO:0004657; GO:0005654; GO:0005739; GO:0005743; GO:0005759; GO:0006560; GO:0006562; GO:0008631; GO:0010133; GO:0010942; GO:0019470; GO:0043231; GO:0071949 46236 XM_029355981.2 717 709 285 950 991 NA NA NA NA NA NA 46237 XM_029339020.2 81 0 0 0 32 NA NA NA NA NA NA 46238 XM_044315356.1 0 0 26 1 17 O60290 1.7e-25 Zinc finger protein 862 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006355; GO:0046872; GO:0046983 46239 XM_044325449.1 1 0 11 3 6 O43854 4.09e-28 EGF-like repeat and discoidin I-like domain-containing protein 3 (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1) Homo sapiens (Human) cell adhesion [GO:0007155]; positive regulation of cell-substrate adhesion [GO:0010811] GO:0005178; GO:0005509; GO:0007155; GO:0010811; GO:0062023; GO:0070062; GO:1903561 46240 XM_044325449.1 1 0 11 3 6 O43854 1.3e-25 EGF-like repeat and discoidin I-like domain-containing protein 3 (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1) Homo sapiens (Human) cell adhesion [GO:0007155]; positive regulation of cell-substrate adhesion [GO:0010811] GO:0005178; GO:0005509; GO:0007155; GO:0010811; GO:0062023; GO:0070062; GO:1903561 46241 XM_029346441.2 223 190 139 227 161 NA NA NA NA NA NA 46242 XM_029345774.2 179 166 215 352 334 NA NA NA NA NA NA 46243 XR_006393521.1 41 43 19 45 24 NA NA NA NA NA NA 46244 XM_044326972.1 7 5 0 0 0 NA NA NA NA NA NA 46245 XM_044326720.1 2955 3029 1373 1409 1826 P23574 3.27e-58 Gamma-aminobutyric acid receptor subunit gamma-1 (GABA(A) receptor subunit gamma-1) Rattus norvegicus (Rat) chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid signaling pathway [GO:0007214]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; regulation of postsynaptic membrane potential [GO:0060078]; signal transduction [GO:0007165]; synaptic transmission, GABAergic [GO:0051932] GO:0004890; GO:0005231; GO:0005237; GO:0005886; GO:0007165; GO:0007214; GO:0007268; GO:0016020; GO:0022851; GO:0030594; GO:0032590; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0043235; GO:0045202; GO:0045211; GO:0050811; GO:0050877; GO:0051932; GO:0060078; GO:0098794; GO:1902476; GO:1902711; GO:1904315 46246 XM_044326720.1 2955 3029 1373 1409 1826 P23574 1.33e-54 Gamma-aminobutyric acid receptor subunit gamma-1 (GABA(A) receptor subunit gamma-1) Rattus norvegicus (Rat) chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid signaling pathway [GO:0007214]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; regulation of postsynaptic membrane potential [GO:0060078]; signal transduction [GO:0007165]; synaptic transmission, GABAergic [GO:0051932] GO:0004890; GO:0005231; GO:0005237; GO:0005886; GO:0007165; GO:0007214; GO:0007268; GO:0016020; GO:0022851; GO:0030594; GO:0032590; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0043235; GO:0045202; GO:0045211; GO:0050811; GO:0050877; GO:0051932; GO:0060078; GO:0098794; GO:1902476; GO:1902711; GO:1904315 46247 XM_044326963.1 19 39 4 44 70 P18294 0 Creatine kinase, flagellar (EC 2.7.3.2) Strongylocentrotus purpuratus (Purple sea urchin) cell projection organization [GO:0030030]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310] GO:0004111; GO:0005524; GO:0005737; GO:0005856; GO:0016301; GO:0016310; GO:0030030; GO:0031514; GO:0046314 46248 XM_044326963.1 19 39 4 44 70 P18294 0 Creatine kinase, flagellar (EC 2.7.3.2) Strongylocentrotus purpuratus (Purple sea urchin) cell projection organization [GO:0030030]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310] GO:0004111; GO:0005524; GO:0005737; GO:0005856; GO:0016301; GO:0016310; GO:0030030; GO:0031514; GO:0046314 46249 XM_044326963.1 19 39 4 44 70 P18294 0 Creatine kinase, flagellar (EC 2.7.3.2) Strongylocentrotus purpuratus (Purple sea urchin) cell projection organization [GO:0030030]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310] GO:0004111; GO:0005524; GO:0005737; GO:0005856; GO:0016301; GO:0016310; GO:0030030; GO:0031514; GO:0046314 46250 XM_044328358.1 8 7 19 5 9 NA NA NA NA NA NA 46251 XR_003823523.2 2 19 2 6 5 NA NA NA NA NA NA 46252 XM_044327078.1 12 10 13 26 34 Q5ZJH6 5.98e-140 Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3) Gallus gallus (Chicken) autophagosome organization [GO:1905037]; negative regulation of smoothened signaling pathway [GO:0045879]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of smoothened signaling pathway [GO:0045880]; protein autophosphorylation [GO:0046777] GO:0000407; GO:0004674; GO:0005524; GO:0005737; GO:0005776; GO:0018105; GO:0045879; GO:0045880; GO:0046777; GO:0106310; GO:1905037 46253 XM_029337860.2 309 337 163 295 229 Q5VTT2 1.26e-43 Cilia- and flagella-associated protein 95 Homo sapiens (Human) NA GO:0005737; GO:0005879; GO:0005886 46254 XM_044313128.1 495 461 485 732 677 A0JMQ0 0 Ribosome biogenesis protein bop1 (Block of proliferation 1 protein) Danio rerio (Zebrafish) (Brachydanio rerio) maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000466]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; regulation of cell cycle [GO:0051726] GO:0000463; GO:0000466; GO:0005654; GO:0030687; GO:0043021; GO:0051726; GO:0070545 46255 XM_029329990.2 442 484 630 511 627 NA NA NA NA NA NA 46256 XM_044307588.1 0 0 24 0 124 NA NA NA NA NA NA 46257 XR_006394812.1 3242 3506 835 3542 2471 NA NA NA NA NA NA 46258 XM_029336184.2 258 132 92 161 144 NA NA NA NA NA NA 46259 XM_044314920.1 60 80 19 0 5 NA NA NA NA NA NA 46260 XR_006397744.1 22 20 10 32 13 NA NA NA NA NA NA 46261 XM_029325038.2 0 0 11 0 4 NA NA NA NA NA NA 46262 XM_029338732.2 52 0 0 0 63 Q80TY4 5.63e-56 Suppression of tumorigenicity 18 protein Mus musculus (Mouse) interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6-mediated signaling pathway [GO:0070102]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000122; GO:0000977; GO:0000978; GO:0000981; GO:0003677; GO:0005634; GO:0006357; GO:0008270; GO:0008285; GO:0032993; GO:0033209; GO:0045944; GO:0070102; GO:0070498; GO:2001269 46263 XM_029338732.2 52 0 0 0 63 Q80TY4 9.43e-34 Suppression of tumorigenicity 18 protein Mus musculus (Mouse) interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6-mediated signaling pathway [GO:0070102]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000122; GO:0000977; GO:0000978; GO:0000981; GO:0003677; GO:0005634; GO:0006357; GO:0008270; GO:0008285; GO:0032993; GO:0033209; GO:0045944; GO:0070102; GO:0070498; GO:2001269 46264 XM_029338732.2 52 0 0 0 63 Q80TY4 8.23e-28 Suppression of tumorigenicity 18 protein Mus musculus (Mouse) interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6-mediated signaling pathway [GO:0070102]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000122; GO:0000977; GO:0000978; GO:0000981; GO:0003677; GO:0005634; GO:0006357; GO:0008270; GO:0008285; GO:0032993; GO:0033209; GO:0045944; GO:0070102; GO:0070498; GO:2001269 46265 XM_029326290.2 3073 3092 2466 4211 4326 Q3ZBN8 2.59e-37 Mitochondrial import inner membrane translocase subunit TIM14 (DnaJ homolog subfamily C member 19) Bos taurus (Bovine) protein import into mitochondrial matrix [GO:0030150]; regulation of cardiolipin metabolic process [GO:1900208] GO:0001405; GO:0001671; GO:0030150; GO:0098800; GO:0099617; GO:1900208 46266 XM_044321827.1 28 41 38 53 68 NA NA NA NA NA NA 46267 XM_029337051.2 0 17 46 0 15 NA NA NA NA NA NA 46268 XM_029350805.2 713 688 626 1000 691 P15848 2.77e-145 Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S) Homo sapiens (Human) autophagy [GO:0006914]; central nervous system development [GO:0007417]; colon epithelial cell migration [GO:0061580]; lysosomal transport [GO:0007041]; lysosome organization [GO:0007040]; positive regulation of neuron projection development [GO:0010976]; regulation of epithelial cell migration [GO:0010632]; response to estrogen [GO:0043627]; response to methylmercury [GO:0051597]; response to nutrient [GO:0007584]; response to pH [GO:0009268] GO:0003943; GO:0004065; GO:0005576; GO:0005739; GO:0005764; GO:0005788; GO:0005791; GO:0005794; GO:0006914; GO:0007040; GO:0007041; GO:0007417; GO:0007584; GO:0009268; GO:0009986; GO:0010632; GO:0010976; GO:0035578; GO:0043202; GO:0043627; GO:0046872; GO:0051597; GO:0061580; GO:0070062; GO:1904813 46269 XR_006394743.1 1097 1044 426 716 532 NA NA NA NA NA NA 46270 XM_044321873.1 49 7 10 0 1192 Q23915 1.54e-28 Probable serine/threonine-protein kinase kinX (EC 2.7.11.1) Dictyostelium discoideum (Social amoeba) protein phosphorylation [GO:0006468]; signal transduction [GO:0007165] GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0006468; GO:0007165; GO:0106310 46271 XM_044322765.1 289 0 0 0 0 Q5PQQ9 1.22e-35 Centrosomal protein of 70 kDa (Cep70) Rattus norvegicus (Rat) cilium assembly [GO:0060271]; regulation of microtubule cytoskeleton organization [GO:0070507] GO:0005737; GO:0005813; GO:0042802; GO:0043015; GO:0060271; GO:0070507 46272 XR_006396231.1 0 0 4 0 20 NA NA NA NA NA NA 46273 XM_029355534.2 0 0 8 0 4 Q2UPB1 5.97e-42 Cytochrome P450 monooxygenase aclC (EC 1.-.-.-) (Aspirochlorine biosynthesis protein C) Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold) NA GO:0004497; GO:0005506; GO:0016705; GO:0020037 46274 XR_003824098.2 75 56 46 44 51 NA NA NA NA NA NA 46275 XM_029349337.2 87 47 35 30 71 NA NA NA NA NA NA 46276 XM_029334884.2 109 121 67 81 91 NA NA NA NA NA NA 46277 XM_044312693.1 99 114 48 8 225 NA NA NA NA NA NA 46278 XM_044313021.1 447 1963 506 449 307 NA NA NA NA NA NA 46279 XM_029325593.2 1756 1335 853 1505 1554 P97379 1.36e-34 Ras GTPase-activating protein-binding protein 2 (G3BP-2) (GAP SH3 domain-binding protein 2) Mus musculus (Mouse) innate immune response [GO:0045087]; mRNA transport [GO:0051028]; positive regulation of stress granule assembly [GO:0062029]; protein homooligomerization [GO:0051260]; small GTPase mediated signal transduction [GO:0007264] GO:0003729; GO:0005829; GO:0007264; GO:0010494; GO:0045087; GO:0051028; GO:0051260; GO:0062029; GO:1990904 46280 XM_029346457.2 1 22 10 30 32 NA NA NA NA NA NA 46281 XM_044309245.1 8 35 0 39 81 NA NA NA NA NA NA 46282 XM_029350458.2 9 0 3 3 16 Q29RU2 5.89e-24 Oncoprotein-induced transcript 3 protein Bos taurus (Bovine) NA GO:0005509; GO:0005635 46283 XM_044312216.1 3 0 5 0 62 NA NA NA NA NA NA 46284 XM_044313516.1 132 10 50 29 81 P32929 0 Cystathionine gamma-lyase (CGL) (CSE) (EC 4.4.1.1) (Cysteine desulfhydrase) (Cysteine-protein sulfhydrase) (Gamma-cystathionase) (Homocysteine desulfhydrase) (EC 4.4.1.2) Homo sapiens (Human) cellular response to leukemia inhibitory factor [GO:1990830]; cysteine biosynthetic process [GO:0019344]; cysteine biosynthetic process via cystathionine [GO:0019343]; cysteine metabolic process [GO:0006534]; endoplasmic reticulum unfolded protein response [GO:0030968]; hydrogen sulfide biosynthetic process [GO:0070814]; lipid metabolic process [GO:0006629]; negative regulation of apoptotic signaling pathway [GO:2001234]; positive regulation of aortic smooth muscle cell differentiation [GO:1904831]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein homotetramerization [GO:0051289]; protein sulfhydration [GO:0044524]; protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine [GO:0018272]; transsulfuration [GO:0019346] GO:0004123; GO:0005516; GO:0005737; GO:0005829; GO:0006534; GO:0006629; GO:0016846; GO:0018272; GO:0019343; GO:0019344; GO:0019346; GO:0030170; GO:0030968; GO:0042802; GO:0043123; GO:0044524; GO:0044540; GO:0047982; GO:0051092; GO:0051289; GO:0070062; GO:0070814; GO:0080146; GO:0098606; GO:1904831; GO:1990830; GO:2001234 46285 XM_044309154.1 263 15 268 103 569 P39059 3.68e-29 Collagen alpha-1(XV) chain [Cleaved into: Restin (Endostatin-XV) (Related to endostatin) (Restin-I); Restin-2 (Restin-II); Restin-3 (Restin-III); Restin-4 (Restin-IV)] Homo sapiens (Human) angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; endothelial cell morphogenesis [GO:0001886]; extracellular matrix organization [GO:0030198]; signal transduction [GO:0007165] GO:0001525; GO:0001886; GO:0005201; GO:0005576; GO:0005582; GO:0005615; GO:0005788; GO:0007155; GO:0007165; GO:0016020; GO:0030020; GO:0030198; GO:0031012; GO:0062023; GO:0070062 46286 XR_006394198.1 0 2 4 3 8 NA NA NA NA NA NA 46287 XM_029332207.2 146 210 63 239 150 NA NA NA NA NA NA 46288 XM_029339377.2 33 89 32 115 45 NA NA NA NA NA NA 46289 XM_029333363.2 375 236 275 205 403 B0BN49 1.05e-66 RNA-binding motif protein, X-linked 2 Rattus norvegicus (Rat) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0003723; GO:0005634; GO:0005686; GO:0071005; GO:0071011 46290 XM_044309773.1 3 0 9 9 59 D3YXG0 1.88e-33 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 46291 XM_044309773.1 3 0 9 9 59 D3YXG0 4.34e-32 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 46292 XM_044309773.1 3 0 9 9 59 D3YXG0 1.52e-30 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 46293 XM_044309773.1 3 0 9 9 59 D3YXG0 9.26e-30 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 46294 XM_044309773.1 3 0 9 9 59 D3YXG0 1.16e-26 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 46295 XM_044309773.1 3 0 9 9 59 D3YXG0 4.38e-26 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 46296 XM_044309773.1 3 0 9 9 59 D3YXG0 5.58e-26 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 46297 XM_044309773.1 3 0 9 9 59 D3YXG0 1.93e-24 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 46298 XM_044309773.1 3 0 9 9 59 D3YXG0 8.13e-24 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 46299 XM_044309773.1 3 0 9 9 59 D3YXG0 1.1e-23 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 46300 XM_044309773.1 3 0 9 9 59 D3YXG0 1.81e-23 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 46301 XM_044309773.1 3 0 9 9 59 D3YXG0 4.92e-23 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 46302 XM_044309773.1 3 0 9 9 59 D3YXG0 1.57e-22 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 46303 XM_044309773.1 3 0 9 9 59 D3YXG0 3.65e-22 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 46304 XM_044309773.1 3 0 9 9 59 D3YXG0 8.1e-22 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 46305 XM_044309773.1 3 0 9 9 59 D3YXG0 9.79e-22 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 46306 XM_044309773.1 3 0 9 9 59 D3YXG0 3.55e-21 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 46307 XM_029351488.2 0 61 0 0 0 Q5TZA2 5.41e-65 Rootletin (Ciliary rootlet coiled-coil protein) Homo sapiens (Human) cellular homeostasis [GO:0019725]; centriole-centriole cohesion [GO:0010457]; centrosome cycle [GO:0007098]; ciliary basal body organization [GO:0032053]; epithelial structure maintenance [GO:0010669]; establishment of localization in cell [GO:0051649]; establishment of organelle localization [GO:0051656]; photoreceptor cell maintenance [GO:0045494]; positive regulation of cilium assembly [GO:0045724]; positive regulation of protein localization to cilium [GO:1903566]; protein localization [GO:0008104]; protein localization to organelle [GO:0033365] GO:0001917; GO:0003779; GO:0005198; GO:0005200; GO:0005813; GO:0005814; GO:0005829; GO:0005886; GO:0007098; GO:0008104; GO:0010457; GO:0010669; GO:0015629; GO:0019725; GO:0019894; GO:0032053; GO:0033365; GO:0035253; GO:0045494; GO:0045724; GO:0051649; GO:0051656; GO:0070062; GO:0097729; GO:0120219; GO:1903566 46308 XM_044322556.1 4 4 0 0 8 NA NA NA NA NA NA 46309 XM_044307785.1 0 0 0 0 491 P47990 0 Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase) (XOR)] Gallus gallus (Chicken) urate biosynthetic process [GO:0034418]; xanthine catabolic process [GO:0009115] GO:0004854; GO:0004855; GO:0005506; GO:0005615; GO:0005777; GO:0005829; GO:0009115; GO:0016491; GO:0030151; GO:0034418; GO:0043546; GO:0050660; GO:0051537; GO:0070674; GO:0071949 46310 XM_044318509.1 1077 46 420 1218 419 Q9ULT8 0 E3 ubiquitin-protein ligase HECTD1 (EC 2.3.2.26) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1) Homo sapiens (Human) anatomical structure development [GO:0048856]; aorta development [GO:0035904]; heart valve development [GO:0003170]; natural killer cell differentiation [GO:0001779]; negative regulation of protein localization to plasma membrane [GO:1903077]; neural tube closure [GO:0001843]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein localization to plasma membrane [GO:0072659]; protein polyubiquitination [GO:0000209]; spongiotrophoblast differentiation [GO:0060708]; trophoblast giant cell differentiation [GO:0060707]; ventricular septum development [GO:0003281] GO:0000209; GO:0001779; GO:0001843; GO:0003170; GO:0003281; GO:0016607; GO:0032436; GO:0035904; GO:0043161; GO:0046872; GO:0048856; GO:0051865; GO:0060707; GO:0060708; GO:0061630; GO:0070534; GO:0072659; GO:1903077 46311 XM_044318509.1 1077 46 420 1218 419 Q9ULT8 2.09e-164 E3 ubiquitin-protein ligase HECTD1 (EC 2.3.2.26) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1) Homo sapiens (Human) anatomical structure development [GO:0048856]; aorta development [GO:0035904]; heart valve development [GO:0003170]; natural killer cell differentiation [GO:0001779]; negative regulation of protein localization to plasma membrane [GO:1903077]; neural tube closure [GO:0001843]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein localization to plasma membrane [GO:0072659]; protein polyubiquitination [GO:0000209]; spongiotrophoblast differentiation [GO:0060708]; trophoblast giant cell differentiation [GO:0060707]; ventricular septum development [GO:0003281] GO:0000209; GO:0001779; GO:0001843; GO:0003170; GO:0003281; GO:0016607; GO:0032436; GO:0035904; GO:0043161; GO:0046872; GO:0048856; GO:0051865; GO:0060707; GO:0060708; GO:0061630; GO:0070534; GO:0072659; GO:1903077 46312 XM_044318509.1 1077 46 420 1218 419 Q9ULT8 5.96e-103 E3 ubiquitin-protein ligase HECTD1 (EC 2.3.2.26) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1) Homo sapiens (Human) anatomical structure development [GO:0048856]; aorta development [GO:0035904]; heart valve development [GO:0003170]; natural killer cell differentiation [GO:0001779]; negative regulation of protein localization to plasma membrane [GO:1903077]; neural tube closure [GO:0001843]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein localization to plasma membrane [GO:0072659]; protein polyubiquitination [GO:0000209]; spongiotrophoblast differentiation [GO:0060708]; trophoblast giant cell differentiation [GO:0060707]; ventricular septum development [GO:0003281] GO:0000209; GO:0001779; GO:0001843; GO:0003170; GO:0003281; GO:0016607; GO:0032436; GO:0035904; GO:0043161; GO:0046872; GO:0048856; GO:0051865; GO:0060707; GO:0060708; GO:0061630; GO:0070534; GO:0072659; GO:1903077 46313 XR_006391476.1 21 11 12 15 48 NA NA NA NA NA NA 46314 XM_029343438.2 9908 10881 6574 16678 9120 NA NA NA NA NA NA 46315 XM_029333976.2 14 20 21 19 49 NA NA NA NA NA NA 46316 XM_029330410.2 0 11 1 0 6 P58308 4.12e-38 Orexin receptor type 2 (Ox-2-R) (Ox2-R) (Ox2R) (Hypocretin receptor type 2) Mus musculus (Mouse) circadian sleep/wake cycle process [GO:0022410]; feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; locomotion [GO:0040011]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; regulation of circadian sleep/wake cycle, wakefulness [GO:0010840]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0004930; GO:0005886; GO:0007186; GO:0007200; GO:0007218; GO:0007631; GO:0010840; GO:0016499; GO:0017046; GO:0022410; GO:0040011; GO:0051480 46317 XM_044321006.1 2073 1167 1284 576 972 NA NA NA NA NA NA 46318 XM_044328517.1 0 0 10 0 0 NA NA NA NA NA NA 46319 XR_006395137.1 13 1 13 6 18 NA NA NA NA NA NA 46320 XM_044328040.1 169 58 55 90 116 Q7Z442 2.23e-75 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Homo sapiens (Human) detection of mechanical stimulus [GO:0050982] GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 46321 XM_044328040.1 169 58 55 90 116 Q7Z442 5.46e-71 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Homo sapiens (Human) detection of mechanical stimulus [GO:0050982] GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 46322 XM_044315709.1 104 0 0 12 78 NA NA NA NA NA NA 46323 XM_029334058.2 7097 11488 6887 8279 4699 P49180 4.6e-30 60S ribosomal protein L35a Caenorhabditis elegans cytoplasmic translation [GO:0002181]; ribosomal large subunit biogenesis [GO:0042273] GO:0002181; GO:0003735; GO:0022625; GO:0042273 46324 XM_044310209.1 19 15 5 4 18 NA NA NA NA NA NA 46325 XM_044329156.1 126 1 118 43 245 Q9NVU0 3.96e-82 DNA-directed RNA polymerase III subunit RPC5 (RNA polymerase III subunit C5) (DNA-directed RNA polymerase III 80 kDa polypeptide) Homo sapiens (Human) defense response to virus [GO:0051607]; DNA-templated transcription [GO:0006351]; innate immune response [GO:0045087] GO:0005654; GO:0005666; GO:0005829; GO:0006351; GO:0045087; GO:0051607 46326 XM_044317457.1 251 575 79 189 224 O62852 2.24e-50 Short transient receptor potential channel 5 (Rtrp5) (TrpC5) (Capacitative calcium entry channel 2) (CCE2) Oryctolagus cuniculus (Rabbit) neuron apoptotic process [GO:0051402]; phosphatidylserine exposure on apoptotic cell surface [GO:0070782] GO:0005262; GO:0005886; GO:0034704; GO:0051402; GO:0070679; GO:0070782 46327 XM_029333745.2 9 0 0 3 5 Q61176 4.14e-82 Arginase-1 (EC 3.5.3.1) (Liver-type arginase) (Type I arginase) Mus musculus (Mouse) adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; negative regulation of type II interferon-mediated signaling pathway [GO:0060336]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; regulation of L-arginine import across plasma membrane [GO:1905541]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to xenobiotic stimulus [GO:0009410]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050] GO:0000050; GO:0001889; GO:0001938; GO:0002250; GO:0004053; GO:0005615; GO:0005737; GO:0005741; GO:0005829; GO:0006525; GO:0007568; GO:0009410; GO:0009635; GO:0010042; GO:0010043; GO:0010269; GO:0014075; GO:0019547; GO:0030145; GO:0030324; GO:0032964; GO:0033189; GO:0033197; GO:0042130; GO:0042802; GO:0042832; GO:0043005; GO:0043025; GO:0043200; GO:0045087; GO:0046007; GO:0046686; GO:0048678; GO:0051597; GO:0060056; GO:0060135; GO:0060336; GO:0070301; GO:0070965; GO:0071222; GO:0071353; GO:0071377; GO:0071549; GO:0071560; GO:1905541; GO:2000552 46328 XM_029329624.2 71 35 22 11 108 A6QPY8 8.51e-25 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 (EC 5.2.1.8) (Parvulin-14) (Par14) (Peptidyl-prolyl cis-trans isomerase Pin4) (PPIase Pin4) (Rotamase Pin4) Bos taurus (Bovine) rRNA processing [GO:0006364] GO:0003677; GO:0003755; GO:0005634; GO:0005654; GO:0005694; GO:0005730; GO:0005737; GO:0005819; GO:0006364 46329 XM_044323772.1 538 399 378 1040 1520 NA NA NA NA NA NA 46330 XR_006391903.1 100 13 12 73 86 Q3UQ28 3.5e-33 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 46331 XR_006391903.1 100 13 12 73 86 Q3UQ28 2.71e-26 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 46332 XM_029345299.2 16 0 0 0 71 NA NA NA NA NA NA 46333 XM_029338491.2 882 504 358 604 502 O15297 3.68e-91 Protein phosphatase 1D (EC 3.1.3.16) (Protein phosphatase 2C isoform delta) (PP2C-delta) (Protein phosphatase magnesium-dependent 1 delta) (p53-induced protein phosphatase 1) Homo sapiens (Human) cellular response to starvation [GO:0009267]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA methylation [GO:0006306]; G2/M transition of mitotic cell cycle [GO:0000086]; heterochromatin formation [GO:0031507]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression, epigenetic [GO:0045814]; peptidyl-threonine dephosphorylation [GO:0035970]; protein dephosphorylation [GO:0006470]; regulation of transcription initiation by RNA polymerase II [GO:0060260]; response to bacterium [GO:0009617]; response to radiation [GO:0009314] GO:0000086; GO:0004674; GO:0004722; GO:0005634; GO:0005654; GO:0005730; GO:0005829; GO:0006306; GO:0006470; GO:0008285; GO:0009267; GO:0009314; GO:0009617; GO:0017018; GO:0030330; GO:0031507; GO:0035970; GO:0045814; GO:0046872; GO:0051019; GO:0060260 46334 XM_029342877.2 13 23 4 53 55 NA NA NA NA NA NA 46335 XM_044311784.1 1 29 11 29 9 NA NA NA NA NA NA 46336 XM_044309608.1 88 13 4 48 13 Q9M2U3 1.22e-25 Protein ALP1-like (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) NA GO:0000118; GO:0004518; GO:0046872 46337 XM_044311396.1 0 0 3 3 12 NA NA NA NA NA NA 46338 XR_006393434.1 12 78 0 53 0 Q924C1 5.88e-52 Exportin-5 (Exp5) (Ran-binding protein 21) Mus musculus (Mouse) positive regulation of post-transcriptional gene silencing by RNA [GO:1900370]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; RNA export from nucleus [GO:0006405] GO:0000049; GO:0003723; GO:0003729; GO:0005049; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006405; GO:0006611; GO:0016442; GO:0031267; GO:0035281; GO:0042565; GO:0070883; GO:1900370; GO:1905172 46339 XM_029342334.2 153 87 129 182 171 NA NA NA NA NA NA 46340 XM_044307172.1 12 0 0 12 4 O15160 5.01e-129 DNA-directed RNA polymerases I and III subunit RPAC1 (DNA-directed RNA polymerase I subunit C) (RNA polymerases I and III subunit AC1) (AC40) (DNA-directed RNA polymerases I and III 40 kDa polypeptide) (RPA40) (RPA39) (RPC40) Homo sapiens (Human) transcription by RNA polymerase I [GO:0006360] GO:0001054; GO:0001056; GO:0001650; GO:0003677; GO:0003899; GO:0005654; GO:0005666; GO:0005736; GO:0005829; GO:0006360; GO:0046983 46341 XM_044327444.1 21 40 25 51 36 Q6L8S8 1.99e-69 Beta-1,4-N-acetylgalactosaminyltransferase 3 (Beta4GalNAc-T3) (Beta4GalNAcT3) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase III) (N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 2) (NGalNAc-T2) Mus musculus (Mouse) chondroitin sulfate biosynthetic process [GO:0030206] GO:0005794; GO:0008376; GO:0030206; GO:0032580; GO:0033842; GO:0043231; GO:0047238 46342 XM_029332386.2 0 53 0 0 0 P78357 1.11e-59 Contactin-associated protein 1 (Caspr) (Caspr1) (Neurexin IV) (Neurexin-4) (p190) Homo sapiens (Human) axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cytoskeleton organization [GO:0007010]; mitochondrion organization [GO:0007005]; myelination in peripheral nervous system [GO:0022011]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; neuron projection morphogenesis [GO:0048812]; neuronal action potential propagation [GO:0019227]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; postsynaptic density organization [GO:0097106]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; regulation of synapse maturation [GO:0090128]; signal transduction [GO:0007165] GO:0002175; GO:0005886; GO:0007005; GO:0007010; GO:0007155; GO:0007165; GO:0007409; GO:0016020; GO:0017124; GO:0019227; GO:0022010; GO:0022011; GO:0030913; GO:0033010; GO:0033270; GO:0038023; GO:0048786; GO:0048812; GO:0050884; GO:0050885; GO:0071205; GO:0090128; GO:0097106; GO:0098529; GO:0098978; GO:1990227 46343 XM_029340528.2 480 243 244 270 455 P35559 0 Insulin-degrading enzyme (EC 3.4.24.56) (Insulin protease) (Insulinase) (Insulysin) Rattus norvegicus (Rat) amyloid-beta clearance [GO:0097242]; amyloid-beta clearance by cellular catabolic process [GO:0150094]; amyloid-beta metabolic process [GO:0050435]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; bradykinin catabolic process [GO:0010815]; determination of adult lifespan [GO:0008340]; hormone catabolic process [GO:0042447]; insulin catabolic process [GO:1901143]; insulin metabolic process [GO:1901142]; insulin receptor recycling [GO:0038020]; negative regulation of proteolysis [GO:0045861]; peptide catabolic process [GO:0043171]; positive regulation of protein binding [GO:0032092]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of aerobic respiration [GO:1903715]; response to oxidative stress [GO:0006979]; ubiquitin recycling [GO:0010992] GO:0001540; GO:0004175; GO:0004222; GO:0005524; GO:0005615; GO:0005634; GO:0005737; GO:0005739; GO:0005777; GO:0005782; GO:0005829; GO:0006508; GO:0006979; GO:0008233; GO:0008270; GO:0008340; GO:0009897; GO:0009986; GO:0010815; GO:0010992; GO:0016323; GO:0016887; GO:0017046; GO:0019885; GO:0030163; GO:0031597; GO:0031626; GO:0031904; GO:0032092; GO:0038020; GO:0042277; GO:0042447; GO:0042802; GO:0042803; GO:0043171; GO:0043559; GO:0044877; GO:0045861; GO:0050435; GO:0051603; GO:0070062; GO:0097242; GO:0140036; GO:0150094; GO:1901142; GO:1901143; GO:1903715 46344 XM_029346541.2 0 0 0 35 3 P49582 4.23e-86 Neuronal acetylcholine receptor subunit alpha-7 Mus musculus (Mouse) acetylcholine receptor signaling pathway [GO:0095500]; associative learning [GO:0008306]; B cell activation [GO:0042113]; behavioral response to ethanol [GO:0048149]; behavioral response to nicotine [GO:0035095]; calcium ion transport [GO:0006816]; chemical synaptic transmission [GO:0007268]; dendrite arborization [GO:0140059]; dendritic spine organization [GO:0097061]; endocytosis [GO:0006897]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; generation of ovulation cycle rhythm [GO:0060112]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; learning or memory [GO:0007611]; membrane depolarization [GO:0051899]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; modulation of excitatory postsynaptic potential [GO:0098815]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of tumor necrosis factor production [GO:0032720]; nervous system process [GO:0050877]; neuronal action potential [GO:0019228]; ovulation cycle [GO:0042698]; positive regulation of acetylcholine biosynthetic process [GO:1905923]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of CoA-transferase activity [GO:1905920]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure [GO:0001988]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of amyloid fibril formation [GO:1905906]; regulation of inflammatory response [GO:0050727]; regulation of membrane potential [GO:0042391]; regulation of neuron death [GO:1901214]; regulation of nitric oxide metabolic process [GO:0080164]; regulation of norepinephrine secretion [GO:0014061]; regulation of response to drug [GO:2001023]; regulation of synapse structural plasticity [GO:0051823]; regulation of synaptic transmission, cholinergic [GO:0032222]; regulation of synaptic transmission, dopaminergic [GO:0032225]; response to acetylcholine [GO:1905144]; response to amyloid-beta [GO:1904645]; response to cold [GO:0009409]; response to ethanol [GO:0045471]; response to food [GO:0032094]; response to nicotine [GO:0035094]; sensory processing [GO:0050893]; signal transduction [GO:0007165]; synapse organization [GO:0050808]; synaptic transmission, cholinergic [GO:0007271]; T cell activation [GO:0042110] GO:0001540; GO:0001933; GO:0001934; GO:0001988; GO:0005216; GO:0005231; GO:0005737; GO:0005886; GO:0005892; GO:0006811; GO:0006816; GO:0006897; GO:0007165; GO:0007268; GO:0007271; GO:0007611; GO:0007613; GO:0008179; GO:0008306; GO:0009409; GO:0009897; GO:0010628; GO:0014061; GO:0014069; GO:0015464; GO:0015643; GO:0016020; GO:0016324; GO:0017081; GO:0019228; GO:0019901; GO:0022848; GO:0030317; GO:0030424; GO:0030425; GO:0030426; GO:0030594; GO:0030673; GO:0032094; GO:0032222; GO:0032225; GO:0032279; GO:0032691; GO:0032715; GO:0032720; GO:0033138; GO:0034220; GO:0035094; GO:0035095; GO:0042110; GO:0042113; GO:0042166; GO:0042391; GO:0042698; GO:0042734; GO:0042803; GO:0043005; GO:0043025; GO:0043197; GO:0043198; GO:0044853; GO:0045121; GO:0045202; GO:0045211; GO:0045471; GO:0048149; GO:0050727; GO:0050728; GO:0050804; GO:0050808; GO:0050877; GO:0050893; GO:0051117; GO:0051247; GO:0051649; GO:0051823; GO:0051899; GO:0060112; GO:0070373; GO:0070374; GO:0080164; GO:0095500; GO:0097061; GO:0097110; GO:0098690; GO:0098793; GO:0098815; GO:0098897; GO:0098981; GO:0099171; GO:0099634; GO:0140059; GO:1900273; GO:1901214; GO:1902004; GO:1904315; GO:1904645; GO:1905144; GO:1905906; GO:1905920; GO:1905923; GO:2000463; GO:2001023 46345 XR_006394056.1 0 9 0 11 0 NA NA NA NA NA NA 46346 XR_003826037.2 4 0 11 0 17 NA NA NA NA NA NA 46347 XM_029335784.2 20 47 15 7 54 P55006 9.55e-78 Retinol dehydrogenase 7 (EC 1.1.1.105) (Retinol dehydrogenase 3) (Retinol dehydrogenase type III) (RODH III) Rattus norvegicus (Rat) retinol metabolic process [GO:0042572]; steroid metabolic process [GO:0008202] GO:0004745; GO:0005783; GO:0008202; GO:0016491; GO:0042572; GO:0043231 46348 XM_044323919.1 2897 1716 1769 3414 3792 Q5T4S7 0 E3 ubiquitin-protein ligase UBR4 (EC 2.3.2.27) (600 kDa retinoblastoma protein-associated factor) (N-recognin-4) (RING-type E3 ubiquitin transferase UBR4) (Retinoblastoma-associated factor of 600 kDa) (RBAF600) (p600) (Zinc finger UBR1-type protein 1) Homo sapiens (Human) ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004842; GO:0005516; GO:0005654; GO:0005813; GO:0005829; GO:0005886; GO:0006511; GO:0008270; GO:0016020; GO:0035579; GO:0061630; GO:0070821; GO:0101003 46349 XM_044323919.1 2897 1716 1769 3414 3792 Q5T4S7 0 E3 ubiquitin-protein ligase UBR4 (EC 2.3.2.27) (600 kDa retinoblastoma protein-associated factor) (N-recognin-4) (RING-type E3 ubiquitin transferase UBR4) (Retinoblastoma-associated factor of 600 kDa) (RBAF600) (p600) (Zinc finger UBR1-type protein 1) Homo sapiens (Human) ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004842; GO:0005516; GO:0005654; GO:0005813; GO:0005829; GO:0005886; GO:0006511; GO:0008270; GO:0016020; GO:0035579; GO:0061630; GO:0070821; GO:0101003 46350 XM_029355383.2 22 0 8 51 11 NA NA NA NA NA NA 46351 XM_029355571.2 1134 699 537 1152 1097 Q6A4L1 8.72e-161 Solute carrier family 12 member 8 Xenopus laevis (African clawed frog) potassium ion transport [GO:0006813] GO:0006813; GO:0015377; GO:0016020 46352 XM_029350172.2 92 9 35 50 101 Q9H8H3 6.56e-51 Putative methyltransferase-like protein 7A (EC 2.1.1.-) (Protein AAM-B) Homo sapiens (Human) methylation [GO:0032259] GO:0005576; GO:0005783; GO:0005811; GO:0008168; GO:0016020; GO:0032259; GO:1904724 46353 XM_044309152.1 28 13 55 53 0 NA NA NA NA NA NA 46354 XM_029350553.2 0 16 54 19 37 Q9BST9 1.3e-52 Rhotekin Homo sapiens (Human) actomyosin contractile ring assembly [GO:0000915]; apoptotic process [GO:0006915]; mitotic cytokinesis [GO:0000281]; regulation of apoptotic process [GO:0042981]; Rho protein signal transduction [GO:0007266]; septin ring organization [GO:0031106]; signal transduction [GO:0007165] GO:0000281; GO:0000915; GO:0005095; GO:0005525; GO:0005826; GO:0005829; GO:0006915; GO:0007165; GO:0007266; GO:0031106; GO:0031267; GO:0042981 46355 XM_044321466.1 405 379 198 466 250 Q6ZV65 1.13e-30 Protein FAM47E Homo sapiens (Human) positive regulation of histone methylation [GO:0031062]; protein localization to chromatin [GO:0071168]; transcription initiation-coupled chromatin remodeling [GO:0045815] GO:0000785; GO:0005634; GO:0005737; GO:0008047; GO:0031062; GO:0045815; GO:0071168 46356 XR_003826764.2 2 16 0 15 13 NA NA NA NA NA NA 46357 XR_006397908.1 11 0 5 1 0 NA NA NA NA NA NA 46358 XM_044317150.1 92 56 56 71 96 Q02410 3.74e-105 Amyloid-beta A4 precursor protein-binding family A member 1 (Adapter protein X11alpha) (Neuron-specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint-1) Homo sapiens (Human) axo-dendritic transport [GO:0008088]; cell adhesion [GO:0007155]; chemical synaptic transmission [GO:0007268]; gamma-aminobutyric acid secretion [GO:0014051]; glutamate secretion [GO:0014047]; in utero embryonic development [GO:0001701]; intracellular protein transport [GO:0006886]; locomotory behavior [GO:0007626]; multicellular organism growth [GO:0035264]; nervous system development [GO:0007399]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; protein-containing complex assembly [GO:0065003]; regulation of gene expression [GO:0010468] GO:0001540; GO:0001701; GO:0005634; GO:0005737; GO:0005794; GO:0005829; GO:0005886; GO:0006886; GO:0007155; GO:0007268; GO:0007399; GO:0007626; GO:0008021; GO:0008088; GO:0010468; GO:0014047; GO:0014051; GO:0035264; GO:0043197; GO:0048471; GO:0048787; GO:0065003; GO:0098685; GO:0098978; GO:0099171 46359 XR_003827113.2 10 0 35 13 73 NA NA NA NA NA NA 46360 XM_029351794.2 61 51 21 42 3 NA NA NA NA NA NA 46361 XM_029358150.2 1042 1394 535 838 640 NA NA NA NA NA NA 46362 XM_029351371.2 144 71 58 77 96 Q5HZI9 1.22e-82 Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51 (Mitochondrial NAD(+) transporter SLC25A51) (Mitochondrial carrier triple repeat protein 1) (Solute carrier family 25 member 51) Mus musculus (Mouse) aerobic electron transport chain [GO:0019646]; mitochondrial NAD transmembrane transport [GO:1990549]; mitochondrial transmembrane transport [GO:1990542] GO:0005739; GO:0005743; GO:0019646; GO:0051724; GO:1990542; GO:1990549 46363 XM_044322676.1 0 0 6 5 29 Q5XI14 2.56e-22 Minichromosome maintenance domain-containing protein 2 (MCM domain-containing protein 2) Rattus norvegicus (Rat) DNA duplex unwinding [GO:0032508]; double-strand break repair involved in meiotic recombination [GO:1990918]; double-strand break repair via break-induced replication [GO:0000727]; late meiotic recombination nodule assembly [GO:0042140]; meiotic recombination nodule assembly [GO:0007146]; oogenesis [GO:0048477]; spermatogenesis [GO:0007283]; synaptonemal complex assembly [GO:0007130] GO:0000727; GO:0003677; GO:0005524; GO:0007130; GO:0007146; GO:0007283; GO:0032508; GO:0042140; GO:0048477; GO:1990918 46364 XM_029351085.2 6 0 0 10 0 NA NA NA NA NA NA 46365 XR_006394884.1 5692 7509 9491 18004 17378 NA NA NA NA NA NA 46366 XM_044326920.1 92 131 75 93 142 NA NA NA NA NA NA 46367 XM_044317903.1 158 37 31 183 259 NA NA NA NA NA NA 46368 XM_029346157.2 0 0 0 0 7 Q9EPI9 0 Potassium voltage-gated channel subfamily H member 5 (Ether-a-go-go potassium channel 2) (rEAG2) (Voltage-gated potassium channel subunit Kv10.2) Rattus norvegicus (Rat) potassium ion transmembrane transport [GO:0071805]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391] GO:0005249; GO:0005516; GO:0005886; GO:0009986; GO:0010389; GO:0034765; GO:0042391; GO:0044325; GO:0044877; GO:0071805 46369 XM_044324900.1 0 0 0 71 0 Q9UQ26 2.17e-62 Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2) (Rab-3-interacting protein 3) Homo sapiens (Human) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-ion regulated exocytosis [GO:0017156]; cell differentiation [GO:0030154]; insulin secretion [GO:0030073]; intracellular protein transport [GO:0006886]; positive regulation of dendrite extension [GO:1903861]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of synaptic transmission [GO:0050806]; regulation of exocytosis [GO:0017157]; regulation of membrane potential [GO:0042391]; regulation of synaptic plasticity [GO:0048167]; spontaneous neurotransmitter secretion [GO:0061669] GO:0006886; GO:0007188; GO:0017156; GO:0017157; GO:0030073; GO:0030154; GO:0031267; GO:0042391; GO:0042734; GO:0042995; GO:0044325; GO:0046872; GO:0048167; GO:0048786; GO:0048788; GO:0048791; GO:0050806; GO:0061669; GO:0070062; GO:0097151; GO:1903861; GO:2000463 46370 XM_044324900.1 0 0 0 71 0 Q9UQ26 8.8e-31 Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2) (Rab-3-interacting protein 3) Homo sapiens (Human) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-ion regulated exocytosis [GO:0017156]; cell differentiation [GO:0030154]; insulin secretion [GO:0030073]; intracellular protein transport [GO:0006886]; positive regulation of dendrite extension [GO:1903861]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of synaptic transmission [GO:0050806]; regulation of exocytosis [GO:0017157]; regulation of membrane potential [GO:0042391]; regulation of synaptic plasticity [GO:0048167]; spontaneous neurotransmitter secretion [GO:0061669] GO:0006886; GO:0007188; GO:0017156; GO:0017157; GO:0030073; GO:0030154; GO:0031267; GO:0042391; GO:0042734; GO:0042995; GO:0044325; GO:0046872; GO:0048167; GO:0048786; GO:0048788; GO:0048791; GO:0050806; GO:0061669; GO:0070062; GO:0097151; GO:1903861; GO:2000463 46371 XM_044328352.1 344 98 241 294 335 Q32PH0 1.92e-152 Trafficking protein particle complex subunit 9 (NIK- and IKBKB-binding protein) Bos taurus (Bovine) cell differentiation [GO:0030154] GO:0005783; GO:0005794; GO:0030154 46372 XM_044320610.1 1 1 7 7 13 NA NA NA NA NA NA 46373 XM_029350712.2 194 0 89 209 562 A0A096X8J7 0 NA NA NA NA 46374 XR_006394817.1 103 0 7 11 56 NA NA NA NA NA NA 46375 XM_029351434.2 0 78 4 10 55 Q6IWL4 1.46e-37 TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6) Danio rerio (Zebrafish) (Brachydanio rerio) innate immune response [GO:0045087]; interleukin-1-mediated signaling pathway [GO:0070498]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of JNK cascade [GO:0046330]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; response to bacterium [GO:0009617]; response to virus [GO:0009615]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0004842; GO:0005164; GO:0005634; GO:0005811; GO:0005938; GO:0008270; GO:0009615; GO:0009617; GO:0032813; GO:0033209; GO:0038061; GO:0042981; GO:0043122; GO:0045087; GO:0045893; GO:0046330; GO:0051092; GO:0061630; GO:0070498; GO:0070534 46376 XM_029337053.2 651 329 517 666 383 Q6IQ20 9.96e-127 N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D (N-acyl phosphatidylethanolamine phospholipase D) (NAPE-PLD) (NAPE-hydrolyzing phospholipase D) (EC 3.1.4.54) Homo sapiens (Human) host-mediated regulation of intestinal microbiota composition [GO:0048874]; N-acylethanolamine metabolic process [GO:0070291]; N-acylphosphatidylethanolamine metabolic process [GO:0070292]; phospholipid catabolic process [GO:0009395]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of inflammatory response [GO:0050729]; retinoid metabolic process [GO:0001523]; temperature homeostasis [GO:0001659] GO:0000139; GO:0001523; GO:0001659; GO:0005635; GO:0005654; GO:0005737; GO:0005769; GO:0005794; GO:0008270; GO:0009395; GO:0031901; GO:0032052; GO:0042622; GO:0042802; GO:0043227; GO:0048874; GO:0050729; GO:0070062; GO:0070290; GO:0070291; GO:0070292; GO:0090336; GO:0102200 46377 XM_029328763.2 110 114 45 27 157 Q5ZL05 1.04e-41 Calcium release-activated calcium channel protein 1 (Protein orai-1) (Transmembrane protein 142A) Gallus gallus (Chicken) adaptive immune response [GO:0002250]; positive regulation of calcium ion transport [GO:0051928]; store-operated calcium entry [GO:0002115] GO:0002115; GO:0002250; GO:0005886; GO:0015279; GO:0016020; GO:0051928 46378 XR_006396307.1 60 0 0 0 0 NA NA NA NA NA NA 46379 XM_044309911.1 3 0 36 0 0 NA NA NA NA NA NA 46380 XM_029335055.2 30 20 24 18 15 NA NA NA NA NA NA 46381 XM_044320663.1 0 6 0 4 4 NA NA NA NA NA NA 46382 XM_044320769.1 144 147 99 118 58 B3EWZ9 0 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 46383 XM_044307746.1 8 1 16 0 52 NA NA NA NA NA NA 46384 XM_029333981.2 281 286 206 359 247 NA NA NA NA NA NA 46385 XM_029339269.2 0 0 0 80 0 Q9N2B7 4.45e-39 5-hydroxytryptamine receptor 1B (5-HT-1B) (5-HT1B) (Serotonin receptor 1B) Gorilla gorilla gorilla (Western lowland gorilla) adenylate cyclase-inhibiting serotonin receptor signaling pathway [GO:0007198]; behavior [GO:0007610]; bone remodeling [GO:0046849]; cellular response to alkaloid [GO:0071312]; cellular response to xenobiotic stimulus [GO:0071466]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; negative regulation of serotonin secretion [GO:0014063]; regulation of behavior [GO:0050795]; vasoconstriction [GO:0042310] GO:0004993; GO:0005886; GO:0007187; GO:0007198; GO:0007268; GO:0007610; GO:0014063; GO:0030425; GO:0030594; GO:0042310; GO:0045202; GO:0046849; GO:0050795; GO:0051378; GO:0071312; GO:0071466 46386 XM_029331208.2 461 340 235 402 254 Q9VZD5 5.79e-25 Probable 28S ribosomal protein S6, mitochondrial (MRP-S6) (S6mt) Drosophila melanogaster (Fruit fly) mitochondrial translation [GO:0032543] GO:0003735; GO:0005763; GO:0032543; GO:0070181 46387 XM_029324789.2 44 54 2 40 28 P83852 8.68e-122 Carboxypeptidase D (EC 3.4.17.22) (CPD-2) (Metallocarboxypeptidase D) Lophonetta specularioides (Crested duck) (Anas specularioides) proteolysis [GO:0006508] GO:0004181; GO:0006508; GO:0008270; GO:0016020 46388 XM_044318420.1 8 13 1 0 10 NA NA NA NA NA NA 46389 XM_044328967.1 161 63 144 137 372 NA NA NA NA NA NA 46390 XM_029356518.2 0 115 0 43 0 NA NA NA NA NA NA 46391 XM_044326634.1 39 14 31 24 11 NA NA NA NA NA NA 46392 XR_006397334.1 707 1400 909 1785 1330 NA NA NA NA NA NA 46393 XM_029342536.2 0 12 13 13 90 Q9EQD2 2.06e-33 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 46394 XM_029333432.2 652 541 373 781 305 Q49LS8 6e-29 XK-related protein 6 Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon nigroviridis) NA GO:0005886 46395 XM_044317830.1 461 4 30 346 77 NA NA NA NA NA NA 46396 XR_006392230.1 0 0 0 36 0 NA NA NA NA NA NA 46397 XM_044312626.1 13 8 5 2 4 NA NA NA NA NA NA 46398 XR_003824485.2 0 0 28 0 15 NA NA NA NA NA NA 46399 XM_044317201.1 0 0 0 12 0 NA NA NA NA NA NA 46400 XM_029358200.2 471 190 74 130 75 NA NA NA NA NA NA 46401 XM_044321079.1 320 377 154 343 56 P28304 4.38e-62 Quinone oxidoreductase 1 (EC 1.6.5.5) (NADPH:quinone reductase 1) (Zeta-crystallin homolog protein) Escherichia coli (strain K12) NA GO:0003960; GO:0005829; GO:0008270; GO:0016651; GO:0070402 46402 XR_006396147.1 0 7 0 0 2 NA NA NA NA NA NA 46403 XM_044318084.1 31 5 8 20 47 Q5F371 7.54e-153 Protein strawberry notch homolog 1 Gallus gallus (Chicken) regulation of DNA-templated transcription [GO:0006355]; regulation of response to stimulus [GO:0048583] GO:0005634; GO:0006355; GO:0031490; GO:0042393; GO:0048583 46404 XM_044309651.1 74 0 0 0 69 A0A3M6TIF0 2.14e-154 NA NA NA NA 46405 XM_044324942.1 325 196 154 367 377 Q8K4M9 0 Oxysterol-binding protein-related protein 1 (ORP-1) (OSBP-related protein 1) Rattus norvegicus (Rat) NA GO:0005768; GO:0005770; GO:0005829; GO:0015248; GO:0015485; GO:0016020; GO:0032934; GO:0043231; GO:0044232 46406 XM_029323989.2 920 674 586 653 735 P13264 0 Glutaminase kidney isoform, mitochondrial (GLS) (EC 3.5.1.2) (K-glutaminase) (L-glutamine amidohydrolase) [Cleaved into: Glutaminase kidney isoform, mitochondrial 68 kDa chain; Glutaminase kidney isoform, mitochondrial 65 kDa chain] Rattus norvegicus (Rat) cellular glutamate homeostasis [GO:0090461]; chemical synaptic transmission [GO:0007268]; glutamate biosynthetic process [GO:0006537]; glutamine catabolic process [GO:0006543]; protein homotetramerization [GO:0051289]; regulation of respiratory gaseous exchange by nervous system process [GO:0002087]; suckling behavior [GO:0001967] GO:0001967; GO:0002087; GO:0004359; GO:0005739; GO:0005759; GO:0005829; GO:0006537; GO:0006543; GO:0007268; GO:0042802; GO:0045202; GO:0051289; GO:0090461 46407 XM_029334128.2 166 46 30 109 87 NA NA NA NA NA NA 46408 XM_044328982.1 25838 46581 96263 14311 281 NA NA NA NA NA NA 46409 XM_029333047.2 183 178 84 139 195 Q9NXG0 2.91e-24 Centlein (Centrosomal protein) Homo sapiens (Human) centriole-centriole cohesion [GO:0010457]; protein localization to organelle [GO:0033365] GO:0005654; GO:0005737; GO:0005813; GO:0005814; GO:0005829; GO:0010457; GO:0019901; GO:0019904; GO:0030674; GO:0033365; GO:0070062 46410 XM_029333047.2 183 178 84 139 195 Q9NXG0 3.8e-21 Centlein (Centrosomal protein) Homo sapiens (Human) centriole-centriole cohesion [GO:0010457]; protein localization to organelle [GO:0033365] GO:0005654; GO:0005737; GO:0005813; GO:0005814; GO:0005829; GO:0010457; GO:0019901; GO:0019904; GO:0030674; GO:0033365; GO:0070062 46411 XM_044314385.1 41 141 40 422 612 Q95SX7 6.36e-37 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 46412 XM_029356051.2 2462 2061 625 1544 2358 Q90YK3 1.91e-164 L-gulonolactone oxidase (LGO) (EC 1.1.3.8) (L-gulono-gamma-lactone oxidase) (GLO) Scyliorhinus torazame (Cloudy catshark) L-ascorbic acid biosynthetic process [GO:0019853] GO:0003885; GO:0005789; GO:0019853; GO:0050105; GO:0050660; GO:0071949 46413 XR_006392632.1 1068 255 172 402 411 Q99715 1.92e-25 Collagen alpha-1(XII) chain Homo sapiens (Human) cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; endodermal cell differentiation [GO:0035987] GO:0005576; GO:0005595; GO:0005615; GO:0005788; GO:0007155; GO:0030020; GO:0030199; GO:0035987; GO:0062023; GO:0070062; GO:1903561 46414 XR_006392632.1 1068 255 172 402 411 Q99715 1.16e-22 Collagen alpha-1(XII) chain Homo sapiens (Human) cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; endodermal cell differentiation [GO:0035987] GO:0005576; GO:0005595; GO:0005615; GO:0005788; GO:0007155; GO:0030020; GO:0030199; GO:0035987; GO:0062023; GO:0070062; GO:1903561 46415 XM_044322130.1 24 0 5 103 4 NA NA NA NA NA NA 46416 XM_044322028.1 167 0 52 167 94 P09487 1.18e-120 Alkaline phosphatase, tissue-nonspecific isozyme (AP-TNAP) (TNAP) (TNSALP) (EC 3.1.3.1) (Alkaline phosphatase liver/bone/kidney isozyme) (Phosphoamidase) (Phosphocreatine phosphatase) (EC 3.9.1.1) Bos taurus (Bovine) biomineral tissue development [GO:0031214]; bone mineralization [GO:0030282]; calcium ion homeostasis [GO:0055074]; cellular homeostasis [GO:0019725]; cellular response to organic cyclic compound [GO:0071407]; dephosphorylation [GO:0016311]; developmental process involved in reproduction [GO:0003006]; endochondral ossification [GO:0001958]; multicellular organism aging [GO:0010259]; phosphate ion homeostasis [GO:0055062]; positive regulation of cold-induced thermogenesis [GO:0120162]; pyridoxal phosphate metabolic process [GO:0042822]; response to antibiotic [GO:0046677]; response to sodium phosphate [GO:1904383]; response to vitamin B6 [GO:0034516]; response to vitamin D [GO:0033280] GO:0001958; GO:0003006; GO:0004035; GO:0004427; GO:0005509; GO:0005758; GO:0005886; GO:0010259; GO:0016311; GO:0016462; GO:0016887; GO:0019725; GO:0030282; GO:0031012; GO:0031214; GO:0031966; GO:0033280; GO:0033883; GO:0034516; GO:0042822; GO:0043262; GO:0046677; GO:0050187; GO:0052732; GO:0055062; GO:0055074; GO:0065010; GO:0071407; GO:0120162; GO:1904383 46417 XR_006394491.1 0 322 0 41 148 NA NA NA NA NA NA 46418 XM_044306843.1 3302 4149 2332 2182 1555 NA NA NA NA NA NA 46419 XM_029323622.2 146 26 12 137 95 NA NA NA NA NA NA 46420 XR_006395371.1 1 0 22 0 19 NA NA NA NA NA NA 46421 XR_006396273.1 162 43 63 210 140 NA NA NA NA NA NA 46422 XM_044322030.1 116 243 80 207 246 NA NA NA NA NA NA 46423 XM_044322036.1 27 34 45 42 42 NA NA NA NA NA NA 46424 XM_044321088.1 75 57 0 74 306 Q9NZJ4 0 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 46425 XM_029330247.2 653 492 502 380 521 NA NA NA NA NA NA 46426 XM_044323117.1 11 19 20 0 40 NA NA NA NA NA NA 46427 XM_044324365.1 375 185 84 254 310 NA NA NA NA NA NA 46428 XM_044313302.1 8 79 28 20 22 NA NA NA NA NA NA 46429 XM_044313531.1 0 0 0 0 8 A0A0C2SRU0 4.43e-78 Decarboxylase iboD (EC 4.1.1.-) (Ibotenic acid biosynthesis cluster protein D) Amanita muscaria (strain Koide BX008) phospholipid biosynthetic process [GO:0008654] GO:0004609; GO:0008654 46430 XM_029336431.2 652 425 701 983 1043 Q9UBH6 1.86e-91 Xenotropic and polytropic retrovirus receptor 1 (Protein SYG1 homolog) (Xenotropic and polytropic murine leukemia virus receptor X3) (X-receptor) Homo sapiens (Human) cellular phosphate ion homeostasis [GO:0030643]; cellular response to phosphate starvation [GO:0016036]; G protein-coupled receptor signaling pathway [GO:0007186]; phosphate ion transmembrane transport [GO:0035435]; phosphate ion transport [GO:0006817]; response to virus [GO:0009615] GO:0000822; GO:0001618; GO:0004888; GO:0004930; GO:0005737; GO:0005794; GO:0005886; GO:0006817; GO:0007186; GO:0009615; GO:0015114; GO:0015562; GO:0016036; GO:0030643; GO:0035435; GO:0038023 46431 XM_044323445.1 13 18 0 16 10 Q5RDB4 3.15e-21 Nuclear envelope integral membrane protein 1 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0005635; GO:0005637 46432 XM_029357055.2 5200 2515 2165 3699 1221 Q9LMG7 1.95e-96 Probable inactive purple acid phosphatase 2 Arabidopsis thaliana (Mouse-ear cress) protein insertion into mitochondrial outer membrane [GO:0045040]; protein targeting to mitochondrion [GO:0006626]; regulation of carbohydrate metabolic process [GO:0006109] GO:0003993; GO:0005576; GO:0005739; GO:0005740; GO:0005768; GO:0005794; GO:0005802; GO:0006109; GO:0006626; GO:0009507; GO:0009941; GO:0030943; GO:0045040; GO:0046872 46433 XM_044325738.1 0 2 7 0 1 NA NA NA NA NA NA 46434 XM_029338702.2 2492 1010 1585 1867 1865 O75116 0 Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, coiled-coil-containing protein kinase 2) (Rho-associated, coiled-coil-containing protein kinase II) (ROCK-II) (p164 ROCK-2) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; actomyosin structure organization [GO:0031032]; aortic valve morphogenesis [GO:0003180]; blood vessel diameter maintenance [GO:0097746]; cellular response to acetylcholine [GO:1905145]; cellular response to testosterone stimulus [GO:0071394]; centrosome duplication [GO:0051298]; cortical actin cytoskeleton organization [GO:0030866]; embryonic morphogenesis [GO:0048598]; epithelial to mesenchymal transition [GO:0001837]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; mitotic cytokinesis [GO:0000281]; modulation by host of viral process [GO:0044788]; mRNA destabilization [GO:0061157]; negative regulation of angiogenesis [GO:0016525]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of gene expression [GO:0010629]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of protein localization to lysosome [GO:0150033]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of amyloid precursor protein catabolic process [GO:1902993]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell migration [GO:0030335]; positive regulation of centrosome duplication [GO:0010825]; positive regulation of connective tissue growth factor production [GO:0032723]; positive regulation of connective tissue replacement [GO:1905205]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of stress fiber assembly [GO:0051496]; protein localization to plasma membrane [GO:0072659]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of angiotensin-activated signaling pathway [GO:0110061]; regulation of cell adhesion [GO:0030155]; regulation of cell junction assembly [GO:1901888]; regulation of cell motility [GO:2000145]; regulation of cellular response to hypoxia [GO:1900037]; regulation of circadian rhythm [GO:0042752]; regulation of establishment of cell polarity [GO:2000114]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of focal adhesion assembly [GO:0051893]; regulation of keratinocyte differentiation [GO:0045616]; regulation of nervous system process [GO:0031644]; regulation of protein metabolic process [GO:0051246]; regulation of stress fiber assembly [GO:0051492]; response to angiotensin [GO:1990776]; response to ischemia [GO:0002931]; response to transforming growth factor beta [GO:0071559]; Rho protein signal transduction [GO:0007266]; rhythmic process [GO:0048511]; smooth muscle contraction [GO:0006939] GO:0000281; GO:0001837; GO:0001934; GO:0002931; GO:0003180; GO:0003723; GO:0004674; GO:0005198; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0005856; GO:0005886; GO:0006468; GO:0006939; GO:0007249; GO:0007266; GO:0010595; GO:0010613; GO:0010628; GO:0010629; GO:0010825; GO:0016525; GO:0018105; GO:0018107; GO:0030036; GO:0030155; GO:0030335; GO:0030866; GO:0031032; GO:0031267; GO:0031644; GO:0032723; GO:0032956; GO:0035509; GO:0036464; GO:0042752; GO:0043410; GO:0044788; GO:0045019; GO:0045616; GO:0046872; GO:0048156; GO:0048511; GO:0048598; GO:0050321; GO:0051246; GO:0051298; GO:0051492; GO:0051496; GO:0051893; GO:0061157; GO:0070168; GO:0071394; GO:0071559; GO:0072518; GO:0072659; GO:0090271; GO:0097746; GO:0106310; GO:0110061; GO:0150033; GO:1900037; GO:1901888; GO:1902004; GO:1902961; GO:1902966; GO:1902993; GO:1903140; GO:1903347; GO:1905145; GO:1905205; GO:1990776; GO:2000114; GO:2000145 46435 XM_044318649.1 1365 497 310 1456 1109 A0A0R4IBK5 0 E3 ubiquitin-protein ligase rnf213-alpha (EC 2.3.2.27) (EC 3.6.4.-) (E3 ubiquitin-lipopolysaccharide ligase rnf213-alpha) (EC 2.3.2.-) (Mysterin-A) (Mysterin-alpha) (RING finger protein 213-A) (RING finger protein 213-alpha) Danio rerio (Zebrafish) (Brachydanio rerio) blood circulation [GO:0008015]; defense response to bacterium [GO:0042742]; immune system process [GO:0002376]; lipid droplet formation [GO:0140042]; lipid ubiquitination [GO:0120323]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein K63-linked ubiquitination [GO:0070534]; regulation of lipid metabolic process [GO:0019216]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]; xenophagy [GO:0098792] GO:0002040; GO:0002376; GO:0004842; GO:0005524; GO:0005730; GO:0005811; GO:0005829; GO:0006511; GO:0008015; GO:0016887; GO:0019216; GO:0042742; GO:0046872; GO:0061630; GO:0070534; GO:0098792; GO:0120323; GO:0140042; GO:2000051 46436 XM_044318649.1 1365 497 310 1456 1109 A0A0R4IBK5 3.96e-124 E3 ubiquitin-protein ligase rnf213-alpha (EC 2.3.2.27) (EC 3.6.4.-) (E3 ubiquitin-lipopolysaccharide ligase rnf213-alpha) (EC 2.3.2.-) (Mysterin-A) (Mysterin-alpha) (RING finger protein 213-A) (RING finger protein 213-alpha) Danio rerio (Zebrafish) (Brachydanio rerio) blood circulation [GO:0008015]; defense response to bacterium [GO:0042742]; immune system process [GO:0002376]; lipid droplet formation [GO:0140042]; lipid ubiquitination [GO:0120323]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein K63-linked ubiquitination [GO:0070534]; regulation of lipid metabolic process [GO:0019216]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]; xenophagy [GO:0098792] GO:0002040; GO:0002376; GO:0004842; GO:0005524; GO:0005730; GO:0005811; GO:0005829; GO:0006511; GO:0008015; GO:0016887; GO:0019216; GO:0042742; GO:0046872; GO:0061630; GO:0070534; GO:0098792; GO:0120323; GO:0140042; GO:2000051 46437 XM_044318649.1 1365 497 310 1456 1109 A0A0R4IBK5 5.86e-74 E3 ubiquitin-protein ligase rnf213-alpha (EC 2.3.2.27) (EC 3.6.4.-) (E3 ubiquitin-lipopolysaccharide ligase rnf213-alpha) (EC 2.3.2.-) (Mysterin-A) (Mysterin-alpha) (RING finger protein 213-A) (RING finger protein 213-alpha) Danio rerio (Zebrafish) (Brachydanio rerio) blood circulation [GO:0008015]; defense response to bacterium [GO:0042742]; immune system process [GO:0002376]; lipid droplet formation [GO:0140042]; lipid ubiquitination [GO:0120323]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein K63-linked ubiquitination [GO:0070534]; regulation of lipid metabolic process [GO:0019216]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]; xenophagy [GO:0098792] GO:0002040; GO:0002376; GO:0004842; GO:0005524; GO:0005730; GO:0005811; GO:0005829; GO:0006511; GO:0008015; GO:0016887; GO:0019216; GO:0042742; GO:0046872; GO:0061630; GO:0070534; GO:0098792; GO:0120323; GO:0140042; GO:2000051 46438 XM_044324200.1 2 0 0 0 23 NA NA NA NA NA NA 46439 XM_044324319.1 1439 1119 670 1362 1194 Q2VUH7 6.84e-68 Dixin (Coiled-coil protein DIX1) (Coiled-coil-DIX1) (DIX domain-containing protein 1) Rattus norvegicus (Rat) canonical Wnt signaling pathway [GO:0060070]; cell proliferation in forebrain [GO:0021846]; cerebellar cortex development [GO:0021695]; cerebral cortex cell migration [GO:0021795]; cerebral cortex radially oriented cell migration [GO:0021799]; forebrain ventricular zone progenitor cell division [GO:0021869]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of axonogenesis [GO:0050772]; positive regulation of JNK cascade [GO:0046330]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of microtubule cytoskeleton organization [GO:0070507] GO:0003779; GO:0005737; GO:0005829; GO:0005856; GO:0005925; GO:0019904; GO:0021695; GO:0021795; GO:0021799; GO:0021846; GO:0021869; GO:0030177; GO:0031435; GO:0032956; GO:0032991; GO:0043015; GO:0043025; GO:0043679; GO:0045665; GO:0046330; GO:0050772; GO:0060070; GO:0070507; GO:0140677 46440 XM_044324319.1 1439 1119 670 1362 1194 Q2VUH7 1.39e-25 Dixin (Coiled-coil protein DIX1) (Coiled-coil-DIX1) (DIX domain-containing protein 1) Rattus norvegicus (Rat) canonical Wnt signaling pathway [GO:0060070]; cell proliferation in forebrain [GO:0021846]; cerebellar cortex development [GO:0021695]; cerebral cortex cell migration [GO:0021795]; cerebral cortex radially oriented cell migration [GO:0021799]; forebrain ventricular zone progenitor cell division [GO:0021869]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of axonogenesis [GO:0050772]; positive regulation of JNK cascade [GO:0046330]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of microtubule cytoskeleton organization [GO:0070507] GO:0003779; GO:0005737; GO:0005829; GO:0005856; GO:0005925; GO:0019904; GO:0021695; GO:0021795; GO:0021799; GO:0021846; GO:0021869; GO:0030177; GO:0031435; GO:0032956; GO:0032991; GO:0043015; GO:0043025; GO:0043679; GO:0045665; GO:0046330; GO:0050772; GO:0060070; GO:0070507; GO:0140677 46441 XM_044312428.1 11 4 0 0 2 NA NA NA NA NA NA 46442 XM_029349229.2 1800 3136 986 3974 4038 NA NA NA NA NA NA 46443 XM_044327392.1 4 6 0 8 0 NA NA NA NA NA NA 46444 XM_044323258.1 0 0 0 48 0 O73792 7.74e-53 Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1) Danio rerio (Zebrafish) (Brachydanio rerio) angiogenesis [GO:0001525]; blood vessel development [GO:0001568]; endothelial cell-cell adhesion [GO:0071603]; heart development [GO:0007507]; positive regulation of angiogenesis [GO:0045766]; positive regulation of kinase activity [GO:0033674]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculature development [GO:0001944] GO:0001525; GO:0001568; GO:0001944; GO:0004714; GO:0005524; GO:0005886; GO:0007169; GO:0007507; GO:0033674; GO:0043235; GO:0045766; GO:0071603 46445 XM_029336616.2 598 534 442 757 702 NA NA NA NA NA NA 46446 XR_003826825.1 5821 11246 5614 7609 4277 NA NA NA NA NA NA 46447 XM_029329095.2 17 0 0 39 0 NA NA NA NA NA NA 46448 XM_044326249.1 1 0 1 2 49 NA NA NA NA NA NA 46449 XM_044317178.1 7 14 3 35 43 NA NA NA NA NA NA 46450 XM_029324359.2 0 24 13 60 52 NA NA NA NA NA NA 46451 XM_044329016.1 124 100 66 78 166 NA NA NA NA NA NA 46452 XM_044322007.1 21827 30500 22260 24167 15246 Q08013 1.55e-73 Translocon-associated protein subunit gamma (TRAP-gamma) (Signal sequence receptor subunit gamma) (SSR-gamma) Rattus norvegicus (Rat) SRP-dependent cotranslational protein targeting to membrane [GO:0006614] GO:0005783; GO:0005784; GO:0006614 46453 XM_029337643.2 368 72 200 195 433 Q5YCC5 7.08e-87 Transmembrane channel-like protein 7 Gallus gallus (Chicken) NA GO:0005886; GO:0008381 46454 XM_044308792.1 383 141 237 270 307 NA NA NA NA NA NA 46455 XM_044328050.1 617 362 381 593 412 Q8VBT9 7.75e-81 Tether containing UBX domain for GLUT4 (Alveolar soft part sarcoma chromosomal region candidate gene 1 protein homolog) Mus musculus (Mouse) glucose homeostasis [GO:0042593]; intracellular protein transport [GO:0006886]; positive regulation of protein modification process [GO:0031401]; regulation of glucose import [GO:0046324] GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0006886; GO:0009898; GO:0012505; GO:0012506; GO:0030659; GO:0031401; GO:0033116; GO:0042593; GO:0043231; GO:0046324; GO:0048471 46456 XM_044327116.1 341 0 154 140 277 Q8WWQ8 0 Stabilin-2 (FAS1 EGF-like and X-link domain-containing adhesion molecule 2) (Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 2) (FEEL-2) (Hyaluronan receptor for endocytosis) [Cleaved into: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)] Homo sapiens (Human) angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; endocytosis [GO:0006897]; hyaluronan catabolic process [GO:0030214]; receptor-mediated endocytosis [GO:0006898] GO:0001525; GO:0005041; GO:0005044; GO:0005509; GO:0005540; GO:0005829; GO:0005886; GO:0006897; GO:0006898; GO:0007155; GO:0009897; GO:0015035; GO:0030169; GO:0030214; GO:0030666; GO:0042742; GO:0050830 46457 XM_044327116.1 341 0 154 140 277 Q8WWQ8 0 Stabilin-2 (FAS1 EGF-like and X-link domain-containing adhesion molecule 2) (Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 2) (FEEL-2) (Hyaluronan receptor for endocytosis) [Cleaved into: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)] Homo sapiens (Human) angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; endocytosis [GO:0006897]; hyaluronan catabolic process [GO:0030214]; receptor-mediated endocytosis [GO:0006898] GO:0001525; GO:0005041; GO:0005044; GO:0005509; GO:0005540; GO:0005829; GO:0005886; GO:0006897; GO:0006898; GO:0007155; GO:0009897; GO:0015035; GO:0030169; GO:0030214; GO:0030666; GO:0042742; GO:0050830 46458 XM_044327116.1 341 0 154 140 277 Q8WWQ8 4.54e-176 Stabilin-2 (FAS1 EGF-like and X-link domain-containing adhesion molecule 2) (Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 2) (FEEL-2) (Hyaluronan receptor for endocytosis) [Cleaved into: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)] Homo sapiens (Human) angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; endocytosis [GO:0006897]; hyaluronan catabolic process [GO:0030214]; receptor-mediated endocytosis [GO:0006898] GO:0001525; GO:0005041; GO:0005044; GO:0005509; GO:0005540; GO:0005829; GO:0005886; GO:0006897; GO:0006898; GO:0007155; GO:0009897; GO:0015035; GO:0030169; GO:0030214; GO:0030666; GO:0042742; GO:0050830 46459 XR_003825672.2 566 193 311 381 1354 NA NA NA NA NA NA 46460 XM_044328371.1 73 144 80 124 132 NA NA NA NA NA NA 46461 XM_044321596.1 267 0 0 247 204 Q80TV8 2.04e-86 CLIP-associating protein 1 (Cytoplasmic linker-associated protein 1) Mus musculus (Mouse) astral microtubule organization [GO:0030953]; cell division [GO:0051301]; cell migration [GO:0016477]; establishment of cell polarity [GO:0030010]; establishment of mitotic spindle localization [GO:0040001]; establishment of spindle orientation [GO:0051294]; exit from mitosis [GO:0010458]; Golgi organization [GO:0007030]; microtubule anchoring [GO:0034453]; microtubule bundle formation [GO:0001578]; microtubule cytoskeleton organization [GO:0000226]; microtubule nucleation [GO:0007020]; microtubule organizing center organization [GO:0031023]; mitotic spindle assembly [GO:0090307]; mitotic spindle organization [GO:0007052]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of microtubule polymerization or depolymerization [GO:0031111]; negative regulation of stress fiber assembly [GO:0051497]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of exocytosis [GO:0045921]; positive regulation of extracellular matrix disassembly [GO:0090091]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of focal adhesion assembly [GO:0051893]; regulation of gastrulation [GO:0010470]; regulation of microtubule cytoskeleton organization [GO:0070507]; vesicle targeting [GO:0006903] GO:0000226; GO:0000776; GO:0001578; GO:0002162; GO:0005737; GO:0005794; GO:0005813; GO:0005815; GO:0005876; GO:0005881; GO:0005925; GO:0005938; GO:0006903; GO:0007020; GO:0007026; GO:0007030; GO:0007052; GO:0008017; GO:0010458; GO:0010470; GO:0010634; GO:0010717; GO:0015630; GO:0016477; GO:0030010; GO:0030953; GO:0030981; GO:0031023; GO:0031111; GO:0031592; GO:0034453; GO:0040001; GO:0043515; GO:0045180; GO:0045921; GO:0051010; GO:0051294; GO:0051301; GO:0051497; GO:0051893; GO:0070507; GO:0072686; GO:0090091; GO:0090307; GO:1903690; GO:1904261 46462 XM_044321596.1 267 0 0 247 204 Q80TV8 6.68e-73 CLIP-associating protein 1 (Cytoplasmic linker-associated protein 1) Mus musculus (Mouse) astral microtubule organization [GO:0030953]; cell division [GO:0051301]; cell migration [GO:0016477]; establishment of cell polarity [GO:0030010]; establishment of mitotic spindle localization [GO:0040001]; establishment of spindle orientation [GO:0051294]; exit from mitosis [GO:0010458]; Golgi organization [GO:0007030]; microtubule anchoring [GO:0034453]; microtubule bundle formation [GO:0001578]; microtubule cytoskeleton organization [GO:0000226]; microtubule nucleation [GO:0007020]; microtubule organizing center organization [GO:0031023]; mitotic spindle assembly [GO:0090307]; mitotic spindle organization [GO:0007052]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of microtubule polymerization or depolymerization [GO:0031111]; negative regulation of stress fiber assembly [GO:0051497]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of exocytosis [GO:0045921]; positive regulation of extracellular matrix disassembly [GO:0090091]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of focal adhesion assembly [GO:0051893]; regulation of gastrulation [GO:0010470]; regulation of microtubule cytoskeleton organization [GO:0070507]; vesicle targeting [GO:0006903] GO:0000226; GO:0000776; GO:0001578; GO:0002162; GO:0005737; GO:0005794; GO:0005813; GO:0005815; GO:0005876; GO:0005881; GO:0005925; GO:0005938; GO:0006903; GO:0007020; GO:0007026; GO:0007030; GO:0007052; GO:0008017; GO:0010458; GO:0010470; GO:0010634; GO:0010717; GO:0015630; GO:0016477; GO:0030010; GO:0030953; GO:0030981; GO:0031023; GO:0031111; GO:0031592; GO:0034453; GO:0040001; GO:0043515; GO:0045180; GO:0045921; GO:0051010; GO:0051294; GO:0051301; GO:0051497; GO:0051893; GO:0070507; GO:0072686; GO:0090091; GO:0090307; GO:1903690; GO:1904261 46463 XM_044321596.1 267 0 0 247 204 Q80TV8 7.68e-49 CLIP-associating protein 1 (Cytoplasmic linker-associated protein 1) Mus musculus (Mouse) astral microtubule organization [GO:0030953]; cell division [GO:0051301]; cell migration [GO:0016477]; establishment of cell polarity [GO:0030010]; establishment of mitotic spindle localization [GO:0040001]; establishment of spindle orientation [GO:0051294]; exit from mitosis [GO:0010458]; Golgi organization [GO:0007030]; microtubule anchoring [GO:0034453]; microtubule bundle formation [GO:0001578]; microtubule cytoskeleton organization [GO:0000226]; microtubule nucleation [GO:0007020]; microtubule organizing center organization [GO:0031023]; mitotic spindle assembly [GO:0090307]; mitotic spindle organization [GO:0007052]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of microtubule polymerization or depolymerization [GO:0031111]; negative regulation of stress fiber assembly [GO:0051497]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of exocytosis [GO:0045921]; positive regulation of extracellular matrix disassembly [GO:0090091]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of focal adhesion assembly [GO:0051893]; regulation of gastrulation [GO:0010470]; regulation of microtubule cytoskeleton organization [GO:0070507]; vesicle targeting [GO:0006903] GO:0000226; GO:0000776; GO:0001578; GO:0002162; GO:0005737; GO:0005794; GO:0005813; GO:0005815; GO:0005876; GO:0005881; GO:0005925; GO:0005938; GO:0006903; GO:0007020; GO:0007026; GO:0007030; GO:0007052; GO:0008017; GO:0010458; GO:0010470; GO:0010634; GO:0010717; GO:0015630; GO:0016477; GO:0030010; GO:0030953; GO:0030981; GO:0031023; GO:0031111; GO:0031592; GO:0034453; GO:0040001; GO:0043515; GO:0045180; GO:0045921; GO:0051010; GO:0051294; GO:0051301; GO:0051497; GO:0051893; GO:0070507; GO:0072686; GO:0090091; GO:0090307; GO:1903690; GO:1904261 46464 XR_006395113.1 309 353 374 943 1306 P0CI65 2.12e-56 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 46465 XR_006395113.1 309 353 374 943 1306 P0CI65 1.72e-49 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 46466 XR_006395113.1 309 353 374 943 1306 P0CI65 1.97e-49 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 46467 XR_006395113.1 309 353 374 943 1306 P0CI65 3.88e-46 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 46468 XR_006395113.1 309 353 374 943 1306 P0CI65 4.36e-39 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 46469 XR_006395113.1 309 353 374 943 1306 P0CI65 1.19e-33 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 46470 XM_029335788.2 290 134 183 175 173 NA NA NA NA NA NA 46471 XM_044321672.1 321 33 0 0 0 P35439 5.89e-53 Glutamate receptor ionotropic, NMDA 1 (GluN1) (Glutamate [NMDA] receptor subunit zeta-1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1) Rattus norvegicus (Rat) adult locomotory behavior [GO:0008344]; associative learning [GO:0008306]; calcium ion homeostasis [GO:0055074]; calcium ion transmembrane import into cytosol [GO:0097553]; calcium ion transport [GO:0006816]; cation transmembrane transport [GO:0098655]; cation transport [GO:0006812]; cellular calcium ion homeostasis [GO:0006874]; cellular response to manganese ion [GO:0071287]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; conditioned taste aversion [GO:0001661]; excitatory postsynaptic potential [GO:0060079]; ionotropic glutamate receptor signaling pathway [GO:0035235]; learning [GO:0007612]; learning or memory [GO:0007611]; long-term memory [GO:0007616]; male mating behavior [GO:0060179]; memory [GO:0007613]; negative regulation of neuron apoptotic process [GO:0043524]; neuromuscular process [GO:0050905]; neuron cellular homeostasis [GO:0070050]; olfactory learning [GO:0008355]; pons maturation [GO:0021586]; positive regulation of apoptotic process [GO:0043065]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of cell death [GO:0010942]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of dendritic spine maintenance [GO:1902952]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of Schwann cell migration [GO:1900149]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; prepulse inhibition [GO:0060134]; propylene metabolic process [GO:0018964]; protein heterotetramerization [GO:0051290]; protein localization to postsynaptic membrane [GO:1903539]; protein-containing complex assembly [GO:0065003]; regulation of axonogenesis [GO:0050770]; regulation of cation transmembrane transport [GO:1904062]; regulation of cell communication [GO:0010646]; regulation of dendrite morphogenesis [GO:0048814]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of membrane potential [GO:0042391]; regulation of neuron apoptotic process [GO:0043523]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of respiratory gaseous exchange [GO:0043576]; regulation of synapse assembly [GO:0051963]; regulation of synaptic plasticity [GO:0048167]; response to amine [GO:0014075]; response to amphetamine [GO:0001975]; response to calcium ion [GO:0051592]; response to ethanol [GO:0045471]; response to fungicide [GO:0060992]; response to glycine [GO:1905429]; response to morphine [GO:0043278]; response to organic cyclic compound [GO:0014070]; rhythmic process [GO:0048511]; sensory perception of pain [GO:0019233]; social behavior [GO:0035176]; startle response [GO:0001964]; suckling behavior [GO:0001967]; synaptic transmission, glutamatergic [GO:0035249]; transcription by RNA polymerase II [GO:0006366]; visual learning [GO:0008542] GO:0001540; GO:0001661; GO:0001964; GO:0001967; GO:0001975; GO:0004970; GO:0004972; GO:0005102; GO:0005261; GO:0005262; GO:0005509; GO:0005516; GO:0005737; GO:0005783; GO:0005789; GO:0005886; GO:0006366; GO:0006812; GO:0006816; GO:0006874; GO:0007268; GO:0007611; GO:0007612; GO:0007613; GO:0007616; GO:0008021; GO:0008306; GO:0008344; GO:0008355; GO:0008542; GO:0009986; GO:0010524; GO:0010646; GO:0010942; GO:0014069; GO:0014070; GO:0014075; GO:0015276; GO:0016020; GO:0016594; GO:0016595; GO:0017146; GO:0018964; GO:0019233; GO:0019899; GO:0019902; GO:0021586; GO:0021987; GO:0022843; GO:0022849; GO:0030425; GO:0030672; GO:0032590; GO:0035176; GO:0035235; GO:0035249; GO:0035254; GO:0038023; GO:0042165; GO:0042391; GO:0042734; GO:0043005; GO:0043025; GO:0043065; GO:0043083; GO:0043195; GO:0043197; GO:0043278; GO:0043523; GO:0043524; GO:0043576; GO:0044307; GO:0044877; GO:0045202; GO:0045211; GO:0045471; GO:0045944; GO:0048167; GO:0048168; GO:0048169; GO:0048511; GO:0048787; GO:0048814; GO:0050770; GO:0050905; GO:0051290; GO:0051592; GO:0051963; GO:0051968; GO:0055074; GO:0060076; GO:0060079; GO:0060134; GO:0060179; GO:0060992; GO:0065003; GO:0070050; GO:0071287; GO:0097060; GO:0097553; GO:0098655; GO:0098686; GO:0098688; GO:0098839; GO:0098978; GO:0099507; GO:1900149; GO:1902952; GO:1903428; GO:1903539; GO:1904062; GO:1904315; GO:1905429; GO:2000463; GO:2001056 46472 XM_044316967.1 0 1 11 3 1 NA NA NA NA NA NA 46473 XM_044311717.1 0 0 59 0 0 A1L0Y2 1.47e-30 Neuralized-like protein 4 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737; GO:0005814 46474 XM_044311717.1 0 0 59 0 0 A1L0Y2 1.47e-30 Neuralized-like protein 4 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737; GO:0005814 46475 XM_044311717.1 0 0 59 0 0 A1L0Y2 5.6e-25 Neuralized-like protein 4 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737; GO:0005814 46476 XM_044311717.1 0 0 59 0 0 A1L0Y2 5.6e-25 Neuralized-like protein 4 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737; GO:0005814 46477 XM_044311717.1 0 0 59 0 0 A1L0Y2 1.89e-22 Neuralized-like protein 4 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737; GO:0005814 46478 XM_044311717.1 0 0 59 0 0 A1L0Y2 1.89e-22 Neuralized-like protein 4 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737; GO:0005814 46479 XM_044311717.1 0 0 59 0 0 A1L0Y2 4.74e-21 Neuralized-like protein 4 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737; GO:0005814 46480 XM_044311717.1 0 0 59 0 0 A1L0Y2 4.74e-21 Neuralized-like protein 4 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737; GO:0005814 46481 XM_044315758.1 8 53 7 8 39 NA NA NA NA NA NA 46482 XR_006392226.1 0 0 0 8 17 NA NA NA NA NA NA 46483 XM_029338318.2 27 29 31 14 50 NA NA NA NA NA NA 46484 XM_029327064.2 898 105 15 499 1 NA NA NA NA NA NA 46485 XM_029351162.2 0 0 0 0 7 NA NA NA NA NA NA 46486 XR_006393037.1 22 0 66 33 15 NA NA NA NA NA NA 46487 XM_029349734.2 1283 634 561 1238 1102 Q149F1 4.26e-142 Pseudouridylate synthase RPUSD2 (EC 5.4.99.-) (RNA pseudouridylate synthase domain-containing protein 2) Mus musculus (Mouse) enzyme-directed rRNA pseudouridine synthesis [GO:0000455]; mRNA processing [GO:0006397]; mRNA pseudouridine synthesis [GO:1990481] GO:0000455; GO:0003723; GO:0006397; GO:0009982; GO:1990481 46488 XM_029353911.2 16 23 0 21 8 NA NA NA NA NA NA 46489 XM_029337957.2 584 261 233 563 414 Q29611 1.48e-110 Battenin (Protein CLN3) Canis lupus familiaris (Dog) (Canis familiaris) amyloid precursor protein catabolic process [GO:0042987]; autophagosome-lysosome fusion [GO:0061909]; cellular water homeostasis [GO:0009992]; glycerophospholipid biosynthetic process [GO:0046474]; glycolipid transport [GO:0046836]; Golgi to lysosome transport [GO:0090160]; L-arginine transmembrane transport [GO:1903826]; learning or memory [GO:0007611]; lysosomal lumen acidification [GO:0007042]; lysosomal lumen pH elevation [GO:0035752]; lysosomal protein catabolic process [GO:1905146]; negative regulation of apoptotic process [GO:0043066]; phagosome-lysosome docking [GO:0090384]; phagosome-lysosome fusion [GO:0090385]; plasma membrane raft organization [GO:0044857]; positive regulation of caveolin-mediated endocytosis [GO:2001288]; positive regulation of Golgi to plasma membrane protein transport [GO:0042998]; positive regulation of pinocytosis [GO:0048549]; receptor-mediated endocytosis [GO:0006898]; regulation of arginine biosynthetic process [GO:1900079]; regulation of autophagosome maturation [GO:1901096]; regulation of cellular response to osmotic stress [GO:0106049]; regulation of cytoskeleton organization [GO:0051493]; regulation of fibroblast migration [GO:0010762]; regulation of modification of synaptic structure [GO:1905244]; regulation of phagosome maturation [GO:1905162]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of protein processing [GO:0070613]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic transmission, GABAergic [GO:0032228]; regulation of synaptic transmission, glutamatergic [GO:0051966]; renal potassium excretion [GO:0036359]; vesicle transport along microtubule [GO:0047496] GO:0000139; GO:0005634; GO:0005737; GO:0005764; GO:0005765; GO:0005769; GO:0005770; GO:0005783; GO:0005789; GO:0005794; GO:0005795; GO:0005802; GO:0005829; GO:0005886; GO:0005901; GO:0006898; GO:0007042; GO:0007611; GO:0008021; GO:0009992; GO:0010762; GO:0016020; GO:0031901; GO:0032228; GO:0035752; GO:0036359; GO:0042987; GO:0042998; GO:0043005; GO:0043066; GO:0044754; GO:0044857; GO:0045121; GO:0046474; GO:0046836; GO:0047496; GO:0048172; GO:0048549; GO:0051493; GO:0051861; GO:0051966; GO:0055037; GO:0061909; GO:0070613; GO:0090160; GO:0090384; GO:0090385; GO:0106049; GO:0120146; GO:1900079; GO:1901096; GO:1903076; GO:1903826; GO:1905146; GO:1905162; GO:1905244; GO:2001288 46490 XM_029357726.2 11 44 7 45 12 NA NA NA NA NA NA 46491 XM_029336251.2 0 138 93 267 194 F1PZV2 5.36e-21 Major facilitator superfamily domain-containing protein 12 Canis lupus familiaris (Dog) (Canis familiaris) carbohydrate transport [GO:0008643]; cysteine transmembrane transport [GO:1903712]; melanin biosynthetic process [GO:0042438]; organic substance transport [GO:0071702]; pigment metabolic process involved in pigmentation [GO:0043474]; regulation of melanin biosynthetic process [GO:0048021] GO:0005764; GO:0005765; GO:0005886; GO:0008643; GO:0015293; GO:0033162; GO:0033229; GO:0042438; GO:0043474; GO:0048021; GO:0071702; GO:1903712 46492 XM_044314931.1 64 0 9 38 14 Q2TBP0 7.92e-40 Proteasome subunit beta type-7 (EC 3.4.25.1) Bos taurus (Bovine) proteolysis involved in protein catabolic process [GO:0051603] GO:0004298; GO:0005634; GO:0005737; GO:0005839; GO:0019774; GO:0051603 46493 XM_029328674.2 297 49 213 486 628 Q640I9 3.64e-123 Lysine-specific demethylase 2B (EC 1.14.11.27) (F-box and leucine-rich repeat protein 10) (F-box/LRR-repeat protein 10) (JmjC domain-containing histone demethylation protein 1B) ([Histone-H3]-lysine-36 demethylase 1B) Xenopus laevis (African clawed frog) chromatin organization [GO:0006325]; histone H3-K36 demethylation [GO:0070544] GO:0005634; GO:0005694; GO:0005730; GO:0006325; GO:0008270; GO:0019843; GO:0045322; GO:0051864; GO:0070544; GO:0140680 46494 XM_029328674.2 297 49 213 486 628 Q640I9 3.38e-61 Lysine-specific demethylase 2B (EC 1.14.11.27) (F-box and leucine-rich repeat protein 10) (F-box/LRR-repeat protein 10) (JmjC domain-containing histone demethylation protein 1B) ([Histone-H3]-lysine-36 demethylase 1B) Xenopus laevis (African clawed frog) chromatin organization [GO:0006325]; histone H3-K36 demethylation [GO:0070544] GO:0005634; GO:0005694; GO:0005730; GO:0006325; GO:0008270; GO:0019843; GO:0045322; GO:0051864; GO:0070544; GO:0140680 46495 XM_029355973.2 300 460 173 244 239 P97343 5.49e-33 Serine/threonine-protein kinase Kist (EC 2.7.11.1) (Kinase interacting with stathmin) (PAM COOH-terminal interactor protein 2) (P-CIP2) (U2AF homology motif kinase 1) Mus musculus (Mouse) neuron projection development [GO:0031175]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of translational initiation [GO:0045948]; protein autophosphorylation [GO:0046777]; regulation of cell cycle [GO:0051726]; regulation of protein export from nucleus [GO:0046825] GO:0003723; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0016607; GO:0018105; GO:0019899; GO:0030424; GO:0031175; GO:0032839; GO:0043021; GO:0043231; GO:0045948; GO:0046777; GO:0046825; GO:0051726; GO:0071598; GO:0106310; GO:1990935 46496 XM_044325222.1 51 37 37 102 93 NA NA NA NA NA NA 46497 XM_044316178.1 1101 268 409 568 402 NA NA NA NA NA NA 46498 XM_044320778.1 9 0 10 0 5 NA NA NA NA NA NA 46499 XM_029355679.2 9 2 12 1 5 NA NA NA NA NA NA 46500 XM_029326565.2 28 17 19 20 25 Q94K49 4.32e-26 Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1 (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) epigenetic regulation of gene expression [GO:0040029] GO:0003682; GO:0004518; GO:0005634; GO:0035098; GO:0035102; GO:0040029; GO:0046872 46501 XM_044323938.1 0 3 16 5 1 Q58L91 2.97e-27 Venom prothrombin activator oscutarin-C non-catalytic subunit (vPA) (Venom coagulation factor Va-like protein) [Cleaved into: Oscutarin-C non-catalytic subunit heavy chain; Oscutarin-C non-catalytic subunit light chain] Oxyuranus scutellatus (Coastal taipan) envenomation resulting in positive regulation of blood coagulation in another organism [GO:0044469]; positive regulation of blood coagulation in another organism [GO:0035807]; positive regulation of peptidase activity [GO:0010952] GO:0005507; GO:0005576; GO:0010952; GO:0016504; GO:0032991; GO:0035807; GO:0044469; GO:0090729 46502 XM_044316405.1 18 3 6 14 35 NA NA NA NA NA NA 46503 XM_029336662.2 269 471 161 312 160 NA NA NA NA NA NA 46504 XM_029330018.2 350 284 76 167 83 NA NA NA NA NA NA 46505 XM_029344840.2 30 18 6 37 5 Q9H3L0 1.47e-67 Cobalamin trafficking protein CblD (CblD) (Methylmalonic aciduria and homocystinuria type D protein, mitochondrial) Homo sapiens (Human) cobalamin metabolic process [GO:0009235] GO:0005737; GO:0005739; GO:0005829; GO:0009235 46506 XM_029351321.2 4621 4405 2657 431 4629 P48506 0 Glutamate--cysteine ligase catalytic subunit (EC 6.3.2.2) (GCS heavy chain) (Gamma-ECS) (Gamma-glutamylcysteine synthetase) Homo sapiens (Human) aging [GO:0007568]; blood vessel diameter maintenance [GO:0097746]; cell redox homeostasis [GO:0045454]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to glucose stimulus [GO:0071333]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to insulin stimulus [GO:0032869]; cellular response to mechanical stimulus [GO:0071260]; cellular response to thyroxine stimulus [GO:0097069]; cysteine metabolic process [GO:0006534]; glutamate metabolic process [GO:0006536]; glutathione biosynthetic process [GO:0006750]; L-ascorbic acid metabolic process [GO:0019852]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of hepatic stellate cell activation [GO:2000490]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; regulation of mitochondrial depolarization [GO:0051900]; response to activity [GO:0014823]; response to arsenic-containing substance [GO:0046685]; response to cadmium ion [GO:0046686]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to human chorionic gonadotropin [GO:0044752]; response to interleukin-1 [GO:0070555]; response to nitrosative stress [GO:0051409]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to xenobiotic stimulus [GO:0009410] GO:0000287; GO:0004357; GO:0005524; GO:0005739; GO:0005829; GO:0006534; GO:0006536; GO:0006750; GO:0006979; GO:0007568; GO:0007584; GO:0009408; GO:0009410; GO:0009725; GO:0014823; GO:0016595; GO:0017109; GO:0019852; GO:0031397; GO:0032436; GO:0032869; GO:0035729; GO:0043066; GO:0043524; GO:0043531; GO:0044344; GO:0044752; GO:0044877; GO:0045454; GO:0045892; GO:0046685; GO:0046686; GO:0051409; GO:0051900; GO:0070555; GO:0071260; GO:0071333; GO:0071372; GO:0097069; GO:0097746; GO:1901029; GO:2000490; GO:2001237 46507 XM_044308623.1 0 12 6 0 0 NA NA NA NA NA NA 46508 XM_029340089.2 42 74 47 0 53 P24524 3.99e-42 Glycine receptor subunit alpha-3 Rattus norvegicus (Rat) cellular response to amino acid stimulus [GO:0071230]; cellular response to ethanol [GO:0071361]; cellular response to zinc ion [GO:0071294]; chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; neuropeptide signaling pathway [GO:0007218]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; protein homooligomerization [GO:0051260]; regulation of membrane potential [GO:0042391]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amino acid [GO:0043200]; signal transduction [GO:0007165]; synaptic transmission, glycinergic [GO:0060012] GO:0004888; GO:0005231; GO:0005886; GO:0007165; GO:0007218; GO:0007268; GO:0016594; GO:0016934; GO:0016935; GO:0022852; GO:0030425; GO:0030594; GO:0034220; GO:0042391; GO:0042734; GO:0043005; GO:0043200; GO:0043204; GO:0045202; GO:0046872; GO:0050877; GO:0051260; GO:0060012; GO:0071230; GO:0071294; GO:0071361; GO:0098690; GO:0098793; GO:0098978; GO:0098982; GO:0099171; GO:0099634; GO:1902476; GO:1904315; GO:2000300 46509 XM_044329300.1 0 15 0 81 0 P08575 9.69e-36 Receptor-type tyrosine-protein phosphatase C (EC 3.1.3.48) (Leukocyte common antigen) (L-CA) (T200) (CD antigen CD45) Homo sapiens (Human) alpha-beta T cell proliferation [GO:0046633]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; B cell receptor signaling pathway [GO:0050853]; bone marrow development [GO:0048539]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell cycle phase transition [GO:0044770]; cell surface receptor signaling pathway [GO:0007166]; cellular response to extracellular stimulus [GO:0031668]; defense response to virus [GO:0051607]; dephosphorylation [GO:0016311]; DN2 thymocyte differentiation [GO:1904155]; extrinsic apoptotic signaling pathway [GO:0097191]; gamma-delta T cell differentiation [GO:0042492]; hematopoietic progenitor cell differentiation [GO:0002244]; heterotypic cell-cell adhesion [GO:0034113]; leukocyte cell-cell adhesion [GO:0007159]; MAPK cascade [GO:0000165]; natural killer cell differentiation [GO:0001779]; negative regulation of cell adhesion involved in substrate-bound cell migration [GO:0006933]; negative regulation of cytokine-mediated signaling pathway [GO:0001960]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of microglial cell activation [GO:1903979]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein tyrosine kinase activity [GO:0061099]; negative regulation of T cell mediated cytotoxicity [GO:0001915]; negative thymic T cell selection [GO:0045060]; peptidyl-tyrosine phosphorylation [GO:0018108]; plasma membrane raft distribution [GO:0044855]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of antigen receptor-mediated signaling pathway [GO:0050857]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis [GO:1905451]; positive regulation of gamma-delta T cell differentiation [GO:0045588]; positive regulation of hematopoietic stem cell migration [GO:2000473]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein tyrosine phosphatase activity [GO:1903615]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tumor necrosis factor production [GO:0032760]; positive thymic T cell selection [GO:0045059]; protein autophosphorylation [GO:0046777]; protein dephosphorylation [GO:0006470]; regulation of cell cycle [GO:0051726]; regulation of gene expression [GO:0010468]; regulation of interleukin-8 production [GO:0032677]; regulation of phagocytosis [GO:0050764]; regulation of protein tyrosine kinase activity [GO:0061097]; regulation of receptor signaling pathway via JAK-STAT [GO:0046425]; release of sequestered calcium ion into cytosol [GO:0051209]; response to gamma radiation [GO:0010332]; stem cell development [GO:0048864]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852] GO:0000165; GO:0001779; GO:0001915; GO:0001916; GO:0001960; GO:0002244; GO:0002639; GO:0002925; GO:0004725; GO:0005001; GO:0005102; GO:0005886; GO:0005925; GO:0006469; GO:0006470; GO:0006933; GO:0007159; GO:0007166; GO:0008201; GO:0009897; GO:0009898; GO:0009986; GO:0010332; GO:0010468; GO:0016020; GO:0016311; GO:0018108; GO:0019901; GO:0030183; GO:0030217; GO:0030506; GO:0030507; GO:0030667; GO:0030890; GO:0031668; GO:0031953; GO:0032059; GO:0032677; GO:0032703; GO:0032743; GO:0032760; GO:0034113; GO:0035584; GO:0042100; GO:0042102; GO:0042110; GO:0042492; GO:0043395; GO:0043406; GO:0043410; GO:0044770; GO:0044855; GO:0045059; GO:0045060; GO:0045121; GO:0045588; GO:0045860; GO:0046425; GO:0046633; GO:0046641; GO:0046777; GO:0048304; GO:0048539; GO:0048864; GO:0050731; GO:0050764; GO:0050852; GO:0050853; GO:0050857; GO:0051209; GO:0051607; GO:0051726; GO:0061097; GO:0061099; GO:0070062; GO:0070373; GO:0070374; GO:0097191; GO:0098857; GO:1903615; GO:1903979; GO:1904155; GO:1905451; GO:2000473; GO:2000648; GO:2001238 46510 XM_044329300.1 0 15 0 81 0 P08575 1.21e-22 Receptor-type tyrosine-protein phosphatase C (EC 3.1.3.48) (Leukocyte common antigen) (L-CA) (T200) (CD antigen CD45) Homo sapiens (Human) alpha-beta T cell proliferation [GO:0046633]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; B cell receptor signaling pathway [GO:0050853]; bone marrow development [GO:0048539]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell cycle phase transition [GO:0044770]; cell surface receptor signaling pathway [GO:0007166]; cellular response to extracellular stimulus [GO:0031668]; defense response to virus [GO:0051607]; dephosphorylation [GO:0016311]; DN2 thymocyte differentiation [GO:1904155]; extrinsic apoptotic signaling pathway [GO:0097191]; gamma-delta T cell differentiation [GO:0042492]; hematopoietic progenitor cell differentiation [GO:0002244]; heterotypic cell-cell adhesion [GO:0034113]; leukocyte cell-cell adhesion [GO:0007159]; MAPK cascade [GO:0000165]; natural killer cell differentiation [GO:0001779]; negative regulation of cell adhesion involved in substrate-bound cell migration [GO:0006933]; negative regulation of cytokine-mediated signaling pathway [GO:0001960]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of microglial cell activation [GO:1903979]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein tyrosine kinase activity [GO:0061099]; negative regulation of T cell mediated cytotoxicity [GO:0001915]; negative thymic T cell selection [GO:0045060]; peptidyl-tyrosine phosphorylation [GO:0018108]; plasma membrane raft distribution [GO:0044855]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of antigen receptor-mediated signaling pathway [GO:0050857]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis [GO:1905451]; positive regulation of gamma-delta T cell differentiation [GO:0045588]; positive regulation of hematopoietic stem cell migration [GO:2000473]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein tyrosine phosphatase activity [GO:1903615]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tumor necrosis factor production [GO:0032760]; positive thymic T cell selection [GO:0045059]; protein autophosphorylation [GO:0046777]; protein dephosphorylation [GO:0006470]; regulation of cell cycle [GO:0051726]; regulation of gene expression [GO:0010468]; regulation of interleukin-8 production [GO:0032677]; regulation of phagocytosis [GO:0050764]; regulation of protein tyrosine kinase activity [GO:0061097]; regulation of receptor signaling pathway via JAK-STAT [GO:0046425]; release of sequestered calcium ion into cytosol [GO:0051209]; response to gamma radiation [GO:0010332]; stem cell development [GO:0048864]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852] GO:0000165; GO:0001779; GO:0001915; GO:0001916; GO:0001960; GO:0002244; GO:0002639; GO:0002925; GO:0004725; GO:0005001; GO:0005102; GO:0005886; GO:0005925; GO:0006469; GO:0006470; GO:0006933; GO:0007159; GO:0007166; GO:0008201; GO:0009897; GO:0009898; GO:0009986; GO:0010332; GO:0010468; GO:0016020; GO:0016311; GO:0018108; GO:0019901; GO:0030183; GO:0030217; GO:0030506; GO:0030507; GO:0030667; GO:0030890; GO:0031668; GO:0031953; GO:0032059; GO:0032677; GO:0032703; GO:0032743; GO:0032760; GO:0034113; GO:0035584; GO:0042100; GO:0042102; GO:0042110; GO:0042492; GO:0043395; GO:0043406; GO:0043410; GO:0044770; GO:0044855; GO:0045059; GO:0045060; GO:0045121; GO:0045588; GO:0045860; GO:0046425; GO:0046633; GO:0046641; GO:0046777; GO:0048304; GO:0048539; GO:0048864; GO:0050731; GO:0050764; GO:0050852; GO:0050853; GO:0050857; GO:0051209; GO:0051607; GO:0051726; GO:0061097; GO:0061099; GO:0070062; GO:0070373; GO:0070374; GO:0097191; GO:0098857; GO:1903615; GO:1903979; GO:1904155; GO:1905451; GO:2000473; GO:2000648; GO:2001238 46511 XR_006395726.1 18 0 0 0 3 NA NA NA NA NA NA 46512 XM_029358314.2 36 8 9 0 64 NA NA NA NA NA NA 46513 XR_006397083.1 49 8 35 16 157 NA NA NA NA NA NA 46514 XM_029338543.2 41 21 39 41 143 NA NA NA NA NA NA 46515 XM_029345542.2 237 54 80 118 178 NA NA NA NA NA NA 46516 XM_044314411.1 320 510 334 931 495 NA NA NA NA NA NA 46517 XM_029337671.2 5855 7952 296 12621 2232 P32674 1.17e-36 Probable dehydratase PflD (EC 4.2.1.-) Escherichia coli (strain K12) NA GO:0005829; GO:0016829 46518 XM_044313468.1 19 0 13 3 104 Q5MD89 4.7e-49 Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) Danio rerio (Zebrafish) (Brachydanio rerio) angiogenesis [GO:0001525]; hematopoietic progenitor cell differentiation [GO:0002244]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; lymphangiogenesis [GO:0001946]; lymphatic endothelial cell differentiation [GO:0060836]; motor neuron axon guidance [GO:0008045]; positive regulation of cell migration [GO:0030335]; positive regulation of kinase activity [GO:0033674]; protein autophosphorylation [GO:0046777]; regulation of MAPK cascade [GO:0043408]; regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030947]; regulation of vascular endothelial growth factor signaling pathway [GO:1900746]; selective angioblast sprouting [GO:0035474]; sprouting angiogenesis [GO:0002040]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculature development [GO:0001944]; venous blood vessel development [GO:0060841]; venous endothelial cell migration involved in lymph vessel development [GO:0060855] GO:0001525; GO:0001944; GO:0001945; GO:0001946; GO:0002040; GO:0002244; GO:0004714; GO:0005021; GO:0005524; GO:0005634; GO:0005737; GO:0005886; GO:0007169; GO:0008045; GO:0030335; GO:0030947; GO:0033674; GO:0035474; GO:0036303; GO:0038084; GO:0042802; GO:0043235; GO:0043408; GO:0046777; GO:0048010; GO:0060836; GO:0060841; GO:0060855; GO:1900746 46519 XM_029336109.2 0 0 0 37 0 O75600 9.36e-173 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial (AKB ligase) (EC 2.3.1.29) (Aminoacetone synthase) (Glycine acetyltransferase) Homo sapiens (Human) amino acid metabolic process [GO:0006520]; biosynthetic process [GO:0009058]; threonine catabolic process [GO:0006567] GO:0005634; GO:0005654; GO:0005739; GO:0005743; GO:0006520; GO:0006567; GO:0008890; GO:0009058; GO:0016607; GO:0030170 46520 XM_029327296.2 156 61 127 200 162 Q9UIU6 4.18e-87 Homeobox protein SIX4 (Sine oculis homeobox homolog 4) Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; embryonic cranial skeleton morphogenesis [GO:0048701]; fungiform papilla morphogenesis [GO:0061197]; generation of neurons [GO:0048699]; inner ear morphogenesis [GO:0042472]; male gonad development [GO:0008584]; male sex determination [GO:0030238]; male sex differentiation [GO:0046661]; metanephric mesenchyme development [GO:0072075]; myoblast migration [GO:0051451]; myotome development [GO:0061055]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of satellite cell differentiation [GO:1902725]; olfactory placode formation [GO:0030910]; pharyngeal system development [GO:0060037]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of ureteric bud formation [GO:0072107]; protein localization to nucleus [GO:0034504]; regulation of branch elongation involved in ureteric bud branching [GO:0072095]; regulation of epithelial cell proliferation [GO:0050678]; regulation of protein localization [GO:0032880]; regulation of synaptic assembly at neuromuscular junction [GO:0008582]; regulation of transcription by RNA polymerase II [GO:0006357]; sarcomere organization [GO:0045214]; skeletal muscle fiber differentiation [GO:0098528]; skeletal muscle tissue development [GO:0007519]; thymus development [GO:0048538]; tongue development [GO:0043586]; trigeminal ganglion development [GO:0061551] GO:0000785; GO:0000978; GO:0000981; GO:0001228; GO:0005634; GO:0005667; GO:0005737; GO:0006357; GO:0007519; GO:0008582; GO:0008584; GO:0009653; GO:0030238; GO:0030910; GO:0032880; GO:0034504; GO:0042472; GO:0043066; GO:0043524; GO:0043586; GO:0045214; GO:0045892; GO:0045893; GO:0046661; GO:0048538; GO:0048699; GO:0048701; GO:0050678; GO:0051451; GO:0060037; GO:0061055; GO:0061197; GO:0061551; GO:0072075; GO:0072095; GO:0072107; GO:0090190; GO:0098528; GO:1902725; GO:1990837 46521 XM_029336823.2 723 407 355 577 670 Q5F3K4 0 WD repeat-containing protein 48 (USP1-associated factor 1) Gallus gallus (Chicken) cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair via homologous recombination [GO:0000724]; embryonic organ development [GO:0048568]; homeostasis of number of cells [GO:0048872]; multicellular organism growth [GO:0035264]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of epithelial cell proliferation [GO:0050679]; regulation of protein monoubiquitination [GO:1902525]; seminiferous tubule development [GO:0072520]; single fertilization [GO:0007338]; skeletal system morphogenesis [GO:0048705]; skin development [GO:0043588]; spermatogenesis [GO:0007283] GO:0000724; GO:0003677; GO:0003690; GO:0003697; GO:0005634; GO:0005764; GO:0005770; GO:0006974; GO:0007283; GO:0007338; GO:0035264; GO:0035800; GO:0043130; GO:0043588; GO:0048568; GO:0048705; GO:0048872; GO:0050679; GO:0072520; GO:1902525; GO:1905168 46522 XM_029336481.1 11455 13201 8676 9670 2703 P24049 5.48e-89 60S ribosomal protein L17 (Amino acid starvation-induced protein) (ASI) (L23) Rattus norvegicus (Rat) cellular response to amino acid starvation [GO:0034198]; cytoplasmic translation [GO:0002181]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; response to amino acid starvation [GO:1990928] GO:0002181; GO:0003735; GO:0005634; GO:0005844; GO:0022625; GO:0022626; GO:0031672; GO:0034198; GO:0045202; GO:0070180; GO:1900087; GO:1990928 46523 XM_044326835.1 2 13 8 16 6 NA NA NA NA NA NA 46524 XM_044308163.1 109 249 155 5 127 D3ZS74 1.82e-73 Metalloendopeptidase OMA1, mitochondrial (EC 3.4.24.-) (Overlapping with the m-AAA protease 1 homolog) Rattus norvegicus (Rat) cristae formation [GO:0042407]; diet induced thermogenesis [GO:0002024]; energy homeostasis [GO:0097009]; glucose metabolic process [GO:0006006]; HRI-mediated signaling [GO:0140468]; integrated stress response signaling [GO:0140467]; lipid metabolic process [GO:0006629]; mitochondrial protein processing [GO:0034982]; mitochondrial respiratory chain complex assembly [GO:0033108]; mitochondrion organization [GO:0007005]; negative regulation of mitochondrial fusion [GO:0010637]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cold-induced thermogenesis [GO:0120162]; protein autoprocessing [GO:0016540]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of cristae formation [GO:1903850]; zymogen activation [GO:0031638] GO:0002024; GO:0004222; GO:0005739; GO:0005743; GO:0006006; GO:0006515; GO:0006629; GO:0007005; GO:0008289; GO:0010637; GO:0016020; GO:0016540; GO:0031638; GO:0031966; GO:0033108; GO:0034982; GO:0042407; GO:0043065; GO:0046872; GO:0051603; GO:0097009; GO:0120162; GO:0140467; GO:0140468; GO:1903850 46525 XM_029343010.2 67 38 10 157 191 E7FAM5 1.85e-88 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 46526 XR_006395704.1 21 0 37 10 195 NA NA NA NA NA NA 46527 XM_029325592.2 2633 2059 1635 5240 3995 NA NA NA NA NA NA 46528 XM_029346048.2 1357 1508 861 1146 1151 O95433 1.04e-103 Activator of 90 kDa heat shock protein ATPase homolog 1 (AHA1) (p38) Homo sapiens (Human) positive regulation of ATP-dependent activity [GO:0032781]; protein folding [GO:0006457] GO:0001671; GO:0005783; GO:0005829; GO:0006457; GO:0032781; GO:0045296; GO:0051087; GO:0051879; GO:0070062 46529 XM_029351511.2 454 416 361 351 374 NA NA NA NA NA NA 46530 XM_029343371.2 78 40 0 60 115 NA NA NA NA NA NA 46531 XM_029330504.2 0 38 76 15 0 Q8IPH9 1.49e-57 Slowpoke-binding protein Drosophila melanogaster (Fruit fly) modulation of chemical synaptic transmission [GO:0050804]; negative regulation of ATP-dependent activity [GO:0032780]; negative regulation of ion transport [GO:0043271]; neuromuscular synaptic transmission [GO:0007274]; regulation of membrane potential [GO:0042391]; response to starvation [GO:0042594] GO:0004672; GO:0005737; GO:0005886; GO:0007274; GO:0032780; GO:0042391; GO:0042594; GO:0043271; GO:0045202; GO:0050804 46532 XM_029353143.2 933 924 567 769 992 NA NA NA NA NA NA 46533 XM_029357141.2 3709 3408 2712 3206 2828 Q8TB05 2.21e-22 UBA-like domain-containing protein 1 Homo sapiens (Human) NA NA 46534 XM_029328741.2 130 211 272 300 353 Q5XGI1 6.78e-112 Kidney mitochondrial carrier protein 1 (Solute carrier family 25 member 30) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) mitochondrial transport [GO:0006839] GO:0005743; GO:0006839 46535 XM_029334944.2 22 17 12 120 29 NA NA NA NA NA NA 46536 XM_044307249.1 8 3 6 5 26 Q92820 4.5e-85 Gamma-glutamyl hydrolase (EC 3.4.19.9) (Conjugase) (GH) (Gamma-Glu-X carboxypeptidase) Homo sapiens (Human) tetrahydrofolylpolyglutamate metabolic process [GO:0046900] GO:0005576; GO:0005615; GO:0005634; GO:0005773; GO:0008238; GO:0008242; GO:0034722; GO:0035578; GO:0035580; GO:0042470; GO:0046900; GO:0070062; GO:1904724 46537 XM_029344266.2 616 429 251 604 565 Q8N567 6.59e-43 Zinc finger CCHC domain-containing protein 9 Homo sapiens (Human) NA GO:0003723; GO:0005654; GO:0005730; GO:0008270 46538 XM_029340269.2 0 266 37 103 154 Q5RA50 1.35e-26 Protein FAM124A Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA NA 46539 XM_044322106.1 2032 0 95 0 663 Q9UA35 4.39e-149 Solute carrier family 28 member 3 (Concentrative Na(+)-nucleoside cotransporter 3) (hfCNT) Eptatretus stoutii (Pacific hagfish) NA GO:0005337; GO:0005886; GO:0015293 46540 XM_029325501.2 239 18 73 243 84 NA NA NA NA NA NA 46541 XM_029329340.2 4030 1524 1336 2482 1798 NA NA NA NA NA NA 46542 XM_044322506.1 30 4 19 44 3 NA NA NA NA NA NA 46543 XR_006394747.1 1855 5520 2222 5813 7861 Q922Q5 4.33e-130 Adenosine 3'-phospho 5'-phosphosulfate transporter 2 (PAPS transporter 2) (Solute carrier family 35 member B3) Mus musculus (Mouse) NA GO:0000139; GO:0005739; GO:0005789; GO:0022857; GO:0046964 46544 XM_044318445.1 12 0 0 0 5 NA NA NA NA NA NA 46545 XM_044322591.1 39 0 0 0 0 C6KFA3 4.38e-21 Adhesion G-protein coupled receptor G6 (G-protein coupled receptor 126) [Cleaved into: ADGRG6 N-terminal fragment (ADGRG6-NTF); ADGRG6 C-terminal fragment (ADGRG6-CTF)] Danio rerio (Zebrafish) (Brachydanio rerio) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cAMP-mediated signaling [GO:0019933]; cell surface receptor signaling pathway [GO:0007166]; ear development [GO:0043583]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; heart trabecula formation [GO:0060347]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; myelination of posterior lateral line nerve axons [GO:0048932]; ossification [GO:0001503]; peripheral nervous system myelin formation [GO:0032290]; regulation of sprouting angiogenesis [GO:1903670]; Schwann cell differentiation [GO:0014037]; semicircular canal fusion [GO:0060879] GO:0001503; GO:0004930; GO:0005518; GO:0005886; GO:0007005; GO:0007166; GO:0007186; GO:0007189; GO:0007507; GO:0014037; GO:0019933; GO:0022011; GO:0032290; GO:0042552; GO:0043236; GO:0043583; GO:0048932; GO:0050840; GO:0060347; GO:0060879; GO:1903670 46546 XM_029335746.2 479 320 254 317 448 F4KD68 4.35e-40 WAT1-related protein At5g45370 Arabidopsis thaliana (Mouse-ear cress) NA GO:0005886; GO:0022857 46547 XR_006395687.1 5 0 2 3 6 NA NA NA NA NA NA 46548 XM_029358459.2 76 0 0 0 38 P54131 3.01e-66 Neuronal acetylcholine receptor subunit alpha-7 Bos taurus (Bovine) calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; cognition [GO:0050890]; ion transmembrane transport [GO:0034220]; negative regulation of tumor necrosis factor production [GO:0032720]; nervous system process [GO:0050877]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAPK cascade [GO:0043410]; regulation of membrane potential [GO:0042391]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271] GO:0001540; GO:0001666; GO:0005231; GO:0005886; GO:0005892; GO:0006816; GO:0006874; GO:0007165; GO:0007268; GO:0007271; GO:0008284; GO:0015464; GO:0015643; GO:0017081; GO:0022848; GO:0030594; GO:0032720; GO:0034220; GO:0035094; GO:0042166; GO:0042391; GO:0042803; GO:0043005; GO:0043410; GO:0045202; GO:0045211; GO:0045766; GO:0050877; GO:0050890; GO:1904315 46549 XM_029347708.2 155 16 9 142 5 NA NA NA NA NA NA 46550 XM_044310560.1 6 152 16 67 57 NA NA NA NA NA NA 46551 XM_044318088.1 9 0 5 13 147 NA NA NA NA NA NA 46552 XM_029349464.2 435 401 141 281 369 NA NA NA NA NA NA 46553 XM_029338719.2 10308 10347 8394 6390 5504 O04287 1.7e-36 Peptidyl-prolyl cis-trans isomerase FKBP12 (PPIase FKBP12) (EC 5.2.1.8) (12 kDa FK506-binding protein) (12 kDa FKBP) (FK506-binding protein 12) (VfFKBP12) (FKBP-12) (Immunophilin FKBP12) (Rotamase) Vicia faba (Broad bean) (Faba vulgaris) NA GO:0003755; GO:0005737 46554 XR_006394473.1 914 292 718 422 991 NA NA NA NA NA NA 46555 XR_006396888.1 2 0 19 0 34 NA NA NA NA NA NA 46556 XM_044313944.1 27 20 5 21 37 B8VIU6 9.67e-52 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 46557 XM_029339381.2 0 0 243 0 0 NA NA NA NA NA NA 46558 XM_029354070.2 10087 11952 12918 8203 7704 NA NA NA NA NA NA 46559 XM_044323769.1 0 15 2 1 7 O75751 1.02e-25 Solute carrier family 22 member 3 (Extraneuronal monoamine transporter) (EMT) (Organic cation transporter 3) Homo sapiens (Human) dopamine uptake [GO:0090494]; epinephrine uptake [GO:0051625]; histamine metabolic process [GO:0001692]; histamine uptake [GO:0051615]; monoamine transport [GO:0015844]; monocarboxylic acid transport [GO:0015718]; neurotransmitter transport [GO:0006836]; norepinephrine uptake [GO:0051620]; organic anion transport [GO:0015711]; organic cation transport [GO:0015695]; purine-containing compound transmembrane transport [GO:0072530]; quaternary ammonium group transport [GO:0015697]; regulation of appetite [GO:0032098]; serotonin uptake [GO:0051610]; spermidine transport [GO:0015848]; toxin transport [GO:1901998]; transport across blood-brain barrier [GO:0150104]; xenobiotic transport [GO:0042908] GO:0001692; GO:0005326; GO:0005886; GO:0006836; GO:0008504; GO:0008514; GO:0015101; GO:0015606; GO:0015651; GO:0015695; GO:0015697; GO:0015711; GO:0015718; GO:0015844; GO:0015848; GO:0016020; GO:0019534; GO:0032098; GO:0042908; GO:0043025; GO:0051610; GO:0051615; GO:0051620; GO:0051625; GO:0072530; GO:0090494; GO:0098793; GO:0150104; GO:1901998 46560 XM_029343270.2 223 410 164 71 277 Q503Z8 4.45e-47 NA NA NA NA 46561 XR_006395533.1 0 0 9 0 0 P53992 0 Protein transport protein Sec24C (SEC24-related protein C) Homo sapiens (Human) COPII-coated vesicle cargo loading [GO:0090110]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; in utero embryonic development [GO:0001701]; intracellular protein transport [GO:0006886] GO:0000149; GO:0001701; GO:0005789; GO:0005829; GO:0006886; GO:0006888; GO:0008270; GO:0012507; GO:0030127; GO:0070971; GO:0090110 46562 XM_044326132.1 0 33 90 144 70 NA NA NA NA NA NA 46563 XM_044315432.1 0 0 0 6 2 P0DP43 1.13e-39 Cation channel sperm-associated auxiliary subunit epsilon (CatSper-epsilon) (CatSperepsilon) (C1orf101-like protein) Mus musculus (Mouse) flagellated sperm motility [GO:0030317]; sperm capacitation [GO:0048240] GO:0030317; GO:0036128; GO:0048240; GO:0097228 46564 XM_029337270.2 211 171 20 10 0 NA NA NA NA NA NA 46565 XM_044320946.1 438 246 136 218 169 Q6DMN8 1.59e-47 Spermatogenesis-associated protein 4 Pan troglodytes (Chimpanzee) regulation of cytoskeleton organization [GO:0051493] GO:0005634; GO:0005930; GO:0008017; GO:0051493 46566 XM_029340155.2 80 0 0 0 0 P97292 3.95e-21 Histamine H2 receptor (H2R) (HH2R) (Gastric receptor I) Mus musculus (Mouse) chemical synaptic transmission [GO:0007268]; digestive tract development [GO:0048565]; epithelial cell morphogenesis [GO:0003382]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; gastric acid secretion [GO:0001696]; gastrin-induced gastric acid secretion [GO:0001698]; gland development [GO:0048732]; histamine-induced gastric acid secretion [GO:0001697]; memory [GO:0007613]; negative regulation of arachidonic acid secretion [GO:1900139]; positive regulation of vasoconstriction [GO:0045907]; regulation of synaptic plasticity [GO:0048167]; toxin transport [GO:1901998]; visual learning [GO:0008542] GO:0001696; GO:0001697; GO:0001698; GO:0003382; GO:0004969; GO:0004993; GO:0005886; GO:0007187; GO:0007268; GO:0007613; GO:0008542; GO:0016020; GO:0030425; GO:0030594; GO:0045202; GO:0045907; GO:0048167; GO:0048565; GO:0048732; GO:1900139; GO:1901363; GO:1901998 46567 XM_044322219.1 618 1032 274 458 534 NA NA NA NA NA NA 46568 XM_029358416.2 1784 190 482 459 461 P08289 7.28e-142 Alkaline phosphatase, tissue-nonspecific isozyme (AP-TNAP) (TNAP) (TNSALP) (EC 3.1.3.1) (Alkaline phosphatase liver/bone/kidney isozyme) (Phosphoamidase) (Phosphocreatine phosphatase) (EC 3.9.1.1) Rattus norvegicus (Rat) bone mineralization [GO:0030282]; calcium ion homeostasis [GO:0055074]; cellular homeostasis [GO:0019725]; cellular response to organic cyclic compound [GO:0071407]; cementum mineralization [GO:0071529]; dephosphorylation [GO:0016311]; developmental process involved in reproduction [GO:0003006]; endochondral ossification [GO:0001958]; futile creatine cycle [GO:0140651]; multicellular organism aging [GO:0010259]; phosphate ion homeostasis [GO:0055062]; positive regulation of cold-induced thermogenesis [GO:0120162]; pyridoxal phosphate metabolic process [GO:0042822]; response to antibiotic [GO:0046677]; response to glucocorticoid [GO:0051384]; response to insulin [GO:0032868]; response to lipopolysaccharide [GO:0032496]; response to macrophage colony-stimulating factor [GO:0036005]; response to organic cyclic compound [GO:0014070]; response to sodium phosphate [GO:1904383]; response to vitamin B6 [GO:0034516]; response to vitamin D [GO:0033280] GO:0001958; GO:0003006; GO:0004035; GO:0004427; GO:0005509; GO:0005615; GO:0005758; GO:0005886; GO:0010259; GO:0014070; GO:0016311; GO:0016462; GO:0016887; GO:0019725; GO:0030282; GO:0031012; GO:0031966; GO:0032496; GO:0032868; GO:0033280; GO:0033883; GO:0034516; GO:0036005; GO:0042822; GO:0043262; GO:0046677; GO:0050187; GO:0051384; GO:0052732; GO:0055062; GO:0055074; GO:0065010; GO:0071407; GO:0071529; GO:0120162; GO:0140651; GO:1904383 46569 XM_044308561.1 257 31 32 86 72 NA NA NA NA NA NA 46570 XM_029357798.2 0 24 9 8 4 Q9EQD2 5.47e-46 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 46571 XR_006397281.1 0 10 0 0 0 NA NA NA NA NA NA 46572 XM_029338889.2 152 43 98 87 262 NA NA NA NA NA NA 46573 XR_006396959.1 265 248 0 265 0 Q8NBS9 6.28e-70 Thioredoxin domain-containing protein 5 (EC 1.8.4.-) (EC 5.3.4.1) (Endoplasmic reticulum resident protein 46) (ER protein 46) (ERp46) (Thioredoxin-like protein p46) Homo sapiens (Human) negative regulation of apoptotic process [GO:0043066]; protein folding [GO:0006457] GO:0003756; GO:0005576; GO:0005783; GO:0005788; GO:0006457; GO:0015035; GO:0035578; GO:0043066; GO:0043202; GO:0070062 46574 XR_006396959.1 265 248 0 265 0 Q8NBS9 3.3e-52 Thioredoxin domain-containing protein 5 (EC 1.8.4.-) (EC 5.3.4.1) (Endoplasmic reticulum resident protein 46) (ER protein 46) (ERp46) (Thioredoxin-like protein p46) Homo sapiens (Human) negative regulation of apoptotic process [GO:0043066]; protein folding [GO:0006457] GO:0003756; GO:0005576; GO:0005783; GO:0005788; GO:0006457; GO:0015035; GO:0035578; GO:0043066; GO:0043202; GO:0070062 46575 XM_029340051.2 11 19 14 34 21 NA NA NA NA NA NA 46576 XM_029350664.2 1807 977 469 1088 896 Q99759 3.08e-43 Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3) Homo sapiens (Human) blood vessel development [GO:0001568]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; negative regulation of cellular senescence [GO:2000773]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell proliferation in bone marrow [GO:0071864]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of p38MAPK cascade [GO:1900745]; protein autophosphorylation [GO:0046777] GO:0000165; GO:0001568; GO:0004672; GO:0004674; GO:0004709; GO:0005524; GO:0005737; GO:0005829; GO:0035556; GO:0043123; GO:0046777; GO:0046872; GO:0071864; GO:0090050; GO:0106310; GO:1900745; GO:2000773 46577 XM_029331850.2 315 158 129 204 298 Q7TPD2 2.11e-22 Protein FAM185A Mus musculus (Mouse) NA NA 46578 XR_006398203.1 297 231 293 252 319 NA NA NA NA NA NA 46579 XM_044328097.1 0 0 0 69 42 NA NA NA NA NA NA 46580 XM_044308630.1 408 250 190 269 324 E7FAM5 8.08e-56 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 46581 XM_029323788.2 14 0 14 36 82 P97292 1.62e-22 Histamine H2 receptor (H2R) (HH2R) (Gastric receptor I) Mus musculus (Mouse) chemical synaptic transmission [GO:0007268]; digestive tract development [GO:0048565]; epithelial cell morphogenesis [GO:0003382]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; gastric acid secretion [GO:0001696]; gastrin-induced gastric acid secretion [GO:0001698]; gland development [GO:0048732]; histamine-induced gastric acid secretion [GO:0001697]; memory [GO:0007613]; negative regulation of arachidonic acid secretion [GO:1900139]; positive regulation of vasoconstriction [GO:0045907]; regulation of synaptic plasticity [GO:0048167]; toxin transport [GO:1901998]; visual learning [GO:0008542] GO:0001696; GO:0001697; GO:0001698; GO:0003382; GO:0004969; GO:0004993; GO:0005886; GO:0007187; GO:0007268; GO:0007613; GO:0008542; GO:0016020; GO:0030425; GO:0030594; GO:0045202; GO:0045907; GO:0048167; GO:0048565; GO:0048732; GO:1900139; GO:1901363; GO:1901998 46582 XM_044326271.1 0 1 25 4 0 NA NA NA NA NA NA 46583 XM_029331328.2 5077 4505 3246 4580 4772 Q9Y5K3 8.69e-101 Choline-phosphate cytidylyltransferase B (EC 2.7.7.15) (CCT-beta) (CTP:phosphocholine cytidylyltransferase B) (CCT B) (CT B) (Phosphorylcholine transferase B) Homo sapiens (Human) CDP-choline pathway [GO:0006657]; ovarian follicle development [GO:0001541]; phosphatidylcholine biosynthetic process [GO:0006656]; spermatogenesis [GO:0007283] GO:0001541; GO:0004105; GO:0005737; GO:0005783; GO:0005789; GO:0006656; GO:0006657; GO:0007283; GO:0031210; GO:0042802 46584 XM_029339259.2 833 698 292 418 935 Q920B9 0 FACT complex subunit SPT16 (Chromatin-specific transcription elongation factor 140 kDa subunit) (FACT 140 kDa subunit) (FACTp140) (Facilitates chromatin transcription complex subunit SPT16) Mus musculus (Mouse) DNA repair [GO:0006281]; DNA replication [GO:0006260]; nucleosome assembly [GO:0006334]; nucleosome disassembly [GO:0006337]; transcription elongation by RNA polymerase II promoter [GO:0006368] GO:0005634; GO:0005654; GO:0006260; GO:0006281; GO:0006334; GO:0006337; GO:0006368; GO:0031491; GO:0035101 46585 XM_044328092.1 1454 730 536 714 670 Q9D1A2 0 Cytosolic non-specific dipeptidase (EC 3.4.13.18) (CNDP dipeptidase 2) (Glutamate carboxypeptidase-like protein 1) (Threonyl dipeptidase) Mus musculus (Mouse) proteolysis [GO:0006508] GO:0004180; GO:0005654; GO:0005829; GO:0006508; GO:0008233; GO:0016805; GO:0046872; GO:0070573; GO:0103046 46586 XM_044308008.1 5 0 0 11 10 Q15032 3.63e-46 R3H domain-containing protein 1 Homo sapiens (Human) NA GO:0003723 46587 XM_044307538.1 573 715 739 1699 1458 Q5RBF1 7.43e-121 NAD-dependent protein deacetylase sirtuin-2 (EC 2.3.1.286) (NAD-dependent protein defatty-acylase sirtuin-2) (EC 2.3.1.-) (Regulatory protein SIR2 homolog 2) (SIR2-like protein 2) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cell cycle [GO:0007049]; cell division [GO:0051301]; cellular lipid catabolic process [GO:0044242]; cellular response to caloric restriction [GO:0061433]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hypoxia [GO:0071456]; cellular response to molecule of bacterial origin [GO:0071219]; cellular response to oxidative stress [GO:0034599]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; myelination in peripheral nervous system [GO:0022011]; negative regulation of autophagy [GO:0010507]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of defense response to bacterium [GO:1900425]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of oligodendrocyte progenitor proliferation [GO:0070446]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061428]; peptidyl-lysine deacetylation [GO:0034983]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of attachment of spindle microtubules to kinetochore [GO:0051987]; positive regulation of cell division [GO:0051781]; positive regulation of DNA binding [GO:0043388]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of meiotic nuclear division [GO:0045836]; positive regulation of oocyte maturation [GO:1900195]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia [GO:2000777]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deacetylation [GO:0006476]; protein kinase B signaling [GO:0043491]; regulation of cell cycle [GO:0051726]; regulation of myelination [GO:0031641]; tubulin deacetylation [GO:0090042] GO:0000122; GO:0000792; GO:0003682; GO:0004407; GO:0005634; GO:0005694; GO:0005737; GO:0005813; GO:0005814; GO:0005819; GO:0005829; GO:0005874; GO:0005886; GO:0006476; GO:0007049; GO:0008285; GO:0010507; GO:0010801; GO:0014065; GO:0022011; GO:0030426; GO:0030496; GO:0031641; GO:0032436; GO:0033010; GO:0033270; GO:0033558; GO:0034599; GO:0034979; GO:0034983; GO:0035729; GO:0042177; GO:0042903; GO:0043161; GO:0043204; GO:0043209; GO:0043219; GO:0043220; GO:0043388; GO:0043491; GO:0044224; GO:0044242; GO:0045599; GO:0045836; GO:0045944; GO:0046872; GO:0046970; GO:0048012; GO:0048471; GO:0051301; GO:0051726; GO:0051781; GO:0051987; GO:0061428; GO:0061433; GO:0070403; GO:0070446; GO:0070932; GO:0070933; GO:0071219; GO:0071456; GO:0071872; GO:0072686; GO:0072687; GO:0090042; GO:0097386; GO:0140773; GO:0140774; GO:1900119; GO:1900195; GO:1900425; GO:2000378; GO:2000777 46588 XR_003823019.2 8 4 11 9 15 NA NA NA NA NA NA 46589 XM_029344286.2 17 50 22 0 57 NA NA NA NA NA NA 46590 XM_029335844.2 25 70 0 3 3 Q8K2J9 2.09e-71 BTB/POZ domain-containing protein 6 Mus musculus (Mouse) neurogenesis [GO:0022008] GO:0005829; GO:0022008 46591 XM_029337139.2 65 67 61 90 104 Q96AY4 3.39e-118 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 46592 XM_029337139.2 65 67 61 90 104 Q96AY4 3.78e-116 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 46593 XM_029337139.2 65 67 61 90 104 Q96AY4 9.8e-87 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 46594 XM_029337139.2 65 67 61 90 104 Q96AY4 3.03e-65 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 46595 XM_029337139.2 65 67 61 90 104 Q96AY4 1.39e-52 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 46596 XM_029337139.2 65 67 61 90 104 Q96AY4 2.47e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 46597 XM_029356320.2 337 905 155 460 8 B8V7S0 5.14e-66 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 46598 XM_029347065.2 13 0 17 3 44 NA NA NA NA NA NA 46599 XR_006392293.1 0 0 0 17 0 NA NA NA NA NA NA 46600 XM_029339849.2 976 714 1034 136 241 Q2TAA2 1.46e-52 Isoamyl acetate-hydrolyzing esterase 1 homolog (EC 3.1.-.-) Homo sapiens (Human) lipid catabolic process [GO:0016042] GO:0016042; GO:0016787; GO:0042802 46601 XM_044317219.1 15 0 0 0 0 NA NA NA NA NA NA 46602 XM_029340973.2 1337 781 427 449 571 NA NA NA NA NA NA 46603 XM_044308976.1 0 0 20 1 0 NA NA NA NA NA NA 46604 XR_006392969.1 27 0 6 0 89 NA NA NA NA NA NA 46605 XM_029340202.2 0 0 0 33 0 NA NA NA NA NA NA 46606 XM_044327801.1 0 0 1 0 16 B8VIU6 6.39e-60 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 46607 XR_006395753.1 27 18 10 0 0 NA NA NA NA NA NA 46608 XM_029336455.2 237 200 85 536 411 NA NA NA NA NA NA 46609 XM_029343117.2 24 7 52 0 175 Q9Z351 3.9e-68 Potassium voltage-gated channel subfamily KQT member 2 (KQT-like 2) (Potassium channel subunit alpha KvLQT2) (Voltage-gated potassium channel subunit Kv7.2) Mus musculus (Mouse) potassium ion transmembrane transport [GO:0071805]; regulation of ion transmembrane transport [GO:0034765]; transmission of nerve impulse [GO:0019226] GO:0005244; GO:0005249; GO:0005251; GO:0005516; GO:0005886; GO:0008076; GO:0009986; GO:0016020; GO:0019226; GO:0030506; GO:0032991; GO:0033268; GO:0034765; GO:0043194; GO:0047485; GO:0071805 46610 XM_029341671.2 0 8 7 0 9 NA NA NA NA NA NA 46611 XM_029331331.2 20 0 0 49 48 Q9YH18 7.1e-58 KH domain-containing RNA-binding protein QKI (Protein quaking) Gallus gallus (Chicken) long-chain fatty acid biosynthetic process [GO:0042759]; mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; myelination [GO:0042552]; positive regulation of gene expression [GO:0010628]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of translation [GO:0006417]; RNA splicing [GO:0008380]; spermatid development [GO:0007286]; vascular associated smooth muscle cell differentiation [GO:0035886]; vasculogenesis [GO:0001570] GO:0001570; GO:0003729; GO:0005634; GO:0005737; GO:0006397; GO:0006417; GO:0007286; GO:0008380; GO:0010628; GO:0017124; GO:0035886; GO:0042552; GO:0042759; GO:0045202; GO:0048024; GO:0051028 46612 XM_029345108.2 0 12 0 0 0 NA NA NA NA NA NA 46613 XM_029323657.2 89 219 17 251 241 Q04786 1.84e-116 Beta-hexosaminidase (EC 3.2.1.52) (Beta-N-acetylhexosaminidase) (Chitobiase) (N-acetyl-beta-glucosaminidase) Vibrio vulnificus chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272] GO:0000272; GO:0004563; GO:0006032; GO:0030247; GO:0102148 46614 XR_006394100.1 345 1 1 14 1 NA NA NA NA NA NA 46615 XM_029324647.2 19 49 34 33 148 Q9EQD2 1.56e-25 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 46616 XM_029342186.2 1221 775 675 1415 1011 Q8TEK3 1.56e-129 Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.360) (DOT1-like protein) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (Lysine N-methyltransferase 4) Homo sapiens (Human) DNA damage checkpoint signaling [GO:0000077]; DNA repair [GO:0006281]; gene expression [GO:0010467]; heterochromatin formation [GO:0031507]; histone H3-K79 methylation [GO:0034729]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of receptor signaling pathway via JAK-STAT [GO:0046425]; regulation of transcription regulatory region DNA binding [GO:2000677]; telomere organization [GO:0032200] GO:0000077; GO:0003676; GO:0003677; GO:0003713; GO:0005634; GO:0005654; GO:0005737; GO:0006281; GO:0008284; GO:0010467; GO:0018024; GO:0031151; GO:0031507; GO:0032200; GO:0032991; GO:0034729; GO:0042054; GO:0043231; GO:0045944; GO:0046425; GO:0061629; GO:0140956; GO:2000677 46617 XR_006395133.1 252 217 73 225 380 NA NA NA NA NA NA 46618 XM_029334367.2 1987 1415 941 952 928 NA NA NA NA NA NA 46619 XM_029326280.2 54 21 19 1 1 NA NA NA NA NA NA 46620 XR_006391417.1 34 6 11 17 7 NA NA NA NA NA NA 46621 XR_003825336.2 201 164 73 172 83 NA NA NA NA NA NA 46622 XM_044324780.1 197 112 256 302 569 NA NA NA NA NA NA 46623 XM_044322065.1 0 0 6 0 167 Q7RTR2 3.48e-25 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 46624 XM_044322065.1 0 0 6 0 167 Q7RTR2 8e-23 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 46625 XM_044308300.1 1520 788 907 1246 760 NA NA NA NA NA NA 46626 XM_029342999.2 3657 5789 2194 5143 6202 NA NA NA NA NA NA 46627 XM_029331334.2 0 42 134 245 109 Q9YH18 5.42e-63 KH domain-containing RNA-binding protein QKI (Protein quaking) Gallus gallus (Chicken) long-chain fatty acid biosynthetic process [GO:0042759]; mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; myelination [GO:0042552]; positive regulation of gene expression [GO:0010628]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of translation [GO:0006417]; RNA splicing [GO:0008380]; spermatid development [GO:0007286]; vascular associated smooth muscle cell differentiation [GO:0035886]; vasculogenesis [GO:0001570] GO:0001570; GO:0003729; GO:0005634; GO:0005737; GO:0006397; GO:0006417; GO:0007286; GO:0008380; GO:0010628; GO:0017124; GO:0035886; GO:0042552; GO:0042759; GO:0045202; GO:0048024; GO:0051028 46628 XM_029350438.2 511 236 353 397 571 Q5BIP7 8.06e-160 Lipoyl synthase, mitochondrial (EC 2.8.1.8) (Lipoate synthase) (LS) (Lip-syn) (Lipoic acid synthase) Bos taurus (Bovine) inflammatory response [GO:0006954]; lipoate biosynthetic process [GO:0009107]; neural tube closure [GO:0001843]; protein lipoylation [GO:0009249]; response to lipopolysaccharide [GO:0032496]; response to oxidative stress [GO:0006979] GO:0001843; GO:0005739; GO:0006954; GO:0006979; GO:0009107; GO:0009249; GO:0016992; GO:0032496; GO:0046872; GO:0051539 46629 XM_044319060.1 331 123 127 226 256 NA NA NA NA NA NA 46630 XM_029341470.2 329 320 121 262 556 NA NA NA NA NA NA 46631 XM_029358041.2 792 323 401 621 499 Q91WD4 1.04e-100 UPF0415 protein C7orf25 homolog Mus musculus (Mouse) NA NA 46632 XM_029342916.2 1519 1352 959 1718 1444 P82094 7.56e-120 TATA element modulatory factor (TMF) (Androgen receptor coactivator 160 kDa protein) (Androgen receptor-associated protein of 160 kDa) Homo sapiens (Human) acrosome assembly [GO:0001675]; androgen receptor signaling pathway [GO:0030521]; defense response to bacterium [GO:0042742]; epithelial cell apoptotic process [GO:1904019]; flagellated sperm motility [GO:0030317]; Leydig cell differentiation [GO:0033327]; luteinizing hormone secretion [GO:0032275]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of gene expression [GO:0010629]; positive regulation of cytokine production [GO:0001819]; positive regulation of testosterone secretion [GO:2000845]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of proteasomal protein catabolic process [GO:0061136]; spermatid nucleus differentiation [GO:0007289] GO:0000139; GO:0001675; GO:0001819; GO:0003677; GO:0005634; GO:0005783; GO:0005794; GO:0005829; GO:0007289; GO:0010629; GO:0030317; GO:0030374; GO:0030521; GO:0032275; GO:0033327; GO:0042742; GO:0045944; GO:0050681; GO:0061136; GO:1904019; GO:1904036; GO:2000845 46633 XM_044310409.1 83 15 41 23 78 NA NA NA NA NA NA 46634 XM_029351237.2 2510 1534 1411 2134 2273 Q66H20 9.59e-144 Polypyrimidine tract-binding protein 2 (Neural polypyrimidine tract-binding protein) (PTB-like protein) Rattus norvegicus (Rat) cerebellum development [GO:0021549]; mRNA splice site selection [GO:0006376]; negative regulation of RNA splicing [GO:0033119]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of RNA splicing [GO:0043484]; spinal cord development [GO:0021510] GO:0003729; GO:0005634; GO:0005681; GO:0006376; GO:0021510; GO:0021549; GO:0030426; GO:0033119; GO:0043025; GO:0043484; GO:2000177 46635 XM_044321256.1 357 1608 382 250 21 NA NA NA NA NA NA 46636 XM_044319283.1 94 0 0 0 0 Q08BM0 4.24e-54 tRNA methyltransferase 10 homolog B (EC 2.1.1.221) (RNA (guanine-9-)-methyltransferase domain-containing protein 3) (tRNA (guanine(9)-N(1))-methyltransferase TRMT10B) Danio rerio (Zebrafish) (Brachydanio rerio) tRNA N1-guanine methylation [GO:0002939] GO:0000049; GO:0002939; GO:0005634; GO:0005654; GO:0009019; GO:0052905 46637 XR_006393446.1 232 233 313 134 319 NA NA NA NA NA NA 46638 XM_029342061.2 668 386 507 685 246 Q569D5 0 Methanethiol oxidase (MTO) (EC 1.8.3.4) (Selenium-binding protein 1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) protein transport [GO:0015031] GO:0005634; GO:0005829; GO:0008430; GO:0015031; GO:0016020; GO:0018549 46639 XM_044320651.1 47 9 42 14 5 Q09575 1.12e-29 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 46640 XM_044324747.1 62 0 0 46 0 Q9UKP5 2.09e-94 A disintegrin and metalloproteinase with thrombospondin motifs 6 (ADAM-TS 6) (ADAM-TS6) (ADAMTS-6) (EC 3.4.24.-) Homo sapiens (Human) aorta development [GO:0035904]; cardiac septum development [GO:0003279]; coronary vasculature development [GO:0060976]; extracellular matrix organization [GO:0030198]; kidney development [GO:0001822]; proteolysis [GO:0006508] GO:0001822; GO:0003279; GO:0004222; GO:0005576; GO:0006508; GO:0008237; GO:0030198; GO:0031012; GO:0035904; GO:0046872; GO:0060976 46641 XM_044314444.1 75 27 264 113 2 NA NA NA NA NA NA 46642 XM_029346495.2 7826 4934 2756 1362 7895 NA NA NA NA NA NA 46643 XM_029324155.2 1417 1458 1285 1194 1551 Q9VMU8 2.45e-104 UDP-galactose transporter senju Drosophila melanogaster (Fruit fly) carbohydrate transport [GO:0008643]; negative regulation of innate immune response [GO:0045824]; negative regulation of Toll signaling pathway [GO:0045751]; positive regulation of antimicrobial peptide production [GO:0002225]; positive regulation of protein glycosylation [GO:0060050]; UDP-galactose transmembrane transport [GO:0072334] GO:0000139; GO:0002225; GO:0005459; GO:0005794; GO:0005797; GO:0008643; GO:0045751; GO:0045824; GO:0060050; GO:0072334 46644 XM_029339618.2 69 26 8 83 35 NA NA NA NA NA NA 46645 XM_029333572.2 20 6 10 25 20 NA NA NA NA NA NA 46646 XM_029326459.2 509 385 238 476 415 A1A5V7 8.21e-83 Transmembrane protein 41B (Protein stasimon) Danio rerio (Zebrafish) (Brachydanio rerio) autophagosome assembly [GO:0000045]; motor neuron axon guidance [GO:0008045] GO:0000045; GO:0005789; GO:0008045; GO:0017128; GO:0044233 46647 XM_029332972.2 268 159 174 281 382 NA NA NA NA NA NA 46648 XM_044312640.1 5 2 7 15 32 NA NA NA NA NA NA 46649 XM_044321883.1 838 514 399 847 680 Q6Q759 7.8e-77 Sperm-associated antigen 17 (Projection protein PF6 homolog) Homo sapiens (Human) axonemal central apparatus assembly [GO:1904158]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; intramanchette transport [GO:1990953]; manchette assembly [GO:1905198]; motile cilium assembly [GO:0044458]; spermatogenesis [GO:0007283] GO:0001669; GO:0002177; GO:0003351; GO:0005576; GO:0005794; GO:0005874; GO:0007283; GO:0031514; GO:0044458; GO:1904158; GO:1905198; GO:1990716; GO:1990953 46650 XM_044321883.1 838 514 399 847 680 Q6Q759 1.82e-62 Sperm-associated antigen 17 (Projection protein PF6 homolog) Homo sapiens (Human) axonemal central apparatus assembly [GO:1904158]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; intramanchette transport [GO:1990953]; manchette assembly [GO:1905198]; motile cilium assembly [GO:0044458]; spermatogenesis [GO:0007283] GO:0001669; GO:0002177; GO:0003351; GO:0005576; GO:0005794; GO:0005874; GO:0007283; GO:0031514; GO:0044458; GO:1904158; GO:1905198; GO:1990716; GO:1990953 46651 XM_044321883.1 838 514 399 847 680 Q6Q759 9.53e-47 Sperm-associated antigen 17 (Projection protein PF6 homolog) Homo sapiens (Human) axonemal central apparatus assembly [GO:1904158]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; intramanchette transport [GO:1990953]; manchette assembly [GO:1905198]; motile cilium assembly [GO:0044458]; spermatogenesis [GO:0007283] GO:0001669; GO:0002177; GO:0003351; GO:0005576; GO:0005794; GO:0005874; GO:0007283; GO:0031514; GO:0044458; GO:1904158; GO:1905198; GO:1990716; GO:1990953 46652 XM_029349432.2 434 354 268 362 907 NA NA NA NA NA NA 46653 XM_029352630.2 114 142 73 166 68 NA NA NA NA NA NA 46654 XM_029351062.2 178 40 124 225 0 Q61072 7.09e-65 Disintegrin and metalloproteinase domain-containing protein 9 (ADAM 9) (EC 3.4.24.-) (Meltrin-gamma) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) Mus musculus (Mouse) amyloid precursor protein catabolic process [GO:0042987]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell migration [GO:0016477]; cell-cell adhesion mediated by integrin [GO:0033631]; cell-matrix adhesion [GO:0007160]; cellular response to lipopolysaccharide [GO:0071222]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; monocyte activation [GO:0042117]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of macrophage fusion [GO:0034241]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of protein secretion [GO:0050714]; protein processing [GO:0016485]; response to calcium ion [GO:0051592]; response to glucocorticoid [GO:0051384]; response to hydrogen peroxide [GO:0042542]; response to manganese ion [GO:0010042]; response to tumor necrosis factor [GO:0034612]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0004222; GO:0005080; GO:0005178; GO:0005518; GO:0005615; GO:0005737; GO:0005886; GO:0006509; GO:0007155; GO:0007160; GO:0007179; GO:0008237; GO:0009897; GO:0009986; GO:0010042; GO:0016323; GO:0016477; GO:0016485; GO:0017124; GO:0030335; GO:0031293; GO:0033627; GO:0033630; GO:0033631; GO:0034241; GO:0034612; GO:0042117; GO:0042542; GO:0042987; GO:0043236; GO:0043406; GO:0046872; GO:0050714; GO:0051044; GO:0051384; GO:0051549; GO:0051592; GO:0071222; GO:1902945 46655 XM_044309288.1 168 58 7 12 72 NA NA NA NA NA NA 46656 XM_044310396.1 0 0 0 0 11 NA NA NA NA NA NA 46657 XM_044317105.1 29 0 0 29 30 NA NA NA NA NA NA 46658 XM_029348080.2 1173 722 922 1430 1035 Q8K268 0 ATP-binding cassette sub-family F member 3 Mus musculus (Mouse) defense response to virus [GO:0051607] GO:0005524; GO:0016887; GO:0051607 46659 XM_029350715.2 673 886 561 511 694 A9ULE9 2.29e-42 DnaJ homolog subfamily C member 22 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0016020 46660 XR_006391385.1 648 946 573 863 778 NA NA NA NA NA NA 46661 XM_029335382.2 15 19 15 17 7 NA NA NA NA NA NA 46662 XM_029346096.2 735 503 381 545 645 NA NA NA NA NA NA 46663 XM_029341196.2 2620 3589 1690 3273 2298 Q6GNL7 0 Cytosolic 10-formyltetrahydrofolate dehydrogenase (10-FTHFDH) (FDH) (EC 1.5.1.6) (Aldehyde dehydrogenase family 1 member L1) Xenopus laevis (African clawed frog) 10-formyltetrahydrofolate catabolic process [GO:0009258]; biosynthetic process [GO:0009058]; NADPH regeneration [GO:0006740]; one-carbon metabolic process [GO:0006730] GO:0005829; GO:0006730; GO:0006740; GO:0009058; GO:0009258; GO:0016155; GO:0016620; GO:0016742 46664 XR_006395308.1 69 89 44 66 69 NA NA NA NA NA NA 46665 XM_044307876.1 100 142 87 55 66 Q6P4F7 1.46e-32 Rho GTPase-activating protein 11A (Rho-type GTPase-activating protein 11A) Homo sapiens (Human) positive regulation of GTPase activity [GO:0043547]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165] GO:0005096; GO:0005634; GO:0005829; GO:0007165; GO:0043547; GO:0051056 46666 XM_044316150.1 14 7 11 3 13 NA NA NA NA NA NA 46667 XR_006392602.1 246 187 199 72 8 NA NA NA NA NA NA 46668 XR_006393109.1 129 82 195 127 315 NA NA NA NA NA NA 46669 XM_029339273.2 0 563 0 0 1689 P53454 1.22e-43 D(5)-like dopamine receptor Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) regulation of biological quality [GO:0065008] GO:0004930; GO:0005886; GO:0065008 46670 XR_006396350.1 8 1 10 26 6 NA NA NA NA NA NA 46671 XM_029358605.2 311 352 269 391 370 Q03393 1.48e-47 6-pyruvoyl tetrahydrobiopterin synthase (PTP synthase) (PTPS) (EC 4.2.3.12) Homo sapiens (Human) amino acid metabolic process [GO:0006520]; central nervous system development [GO:0007417]; tetrahydrobiopterin biosynthetic process [GO:0006729] GO:0003874; GO:0005737; GO:0005739; GO:0005829; GO:0006520; GO:0006729; GO:0007417; GO:0042802; GO:0046872 46672 XR_003826994.2 10 15 5 5 19 NA NA NA NA NA NA 46673 XM_044308374.1 22 9 22 15 32 A0JPE9 4.62e-168 Putative glycerol kinase 5 (GK 5) (Glycerokinase 5) (EC 2.7.1.30) (ATP:glycerol 3-phosphotransferase 5) Danio rerio (Zebrafish) (Brachydanio rerio) glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate biosynthetic process [GO:0046167]; phosphorylation [GO:0016310]; triglyceride metabolic process [GO:0006641] GO:0004370; GO:0005524; GO:0005739; GO:0006071; GO:0006641; GO:0016310; GO:0019563; GO:0046167 46674 XM_044317379.1 0 3 0 50 15 Q96AY4 1.65e-47 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 46675 XM_044317379.1 0 3 0 50 15 Q96AY4 9.73e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 46676 XM_044317379.1 0 3 0 50 15 Q96AY4 1.99e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 46677 XM_044317379.1 0 3 0 50 15 Q96AY4 1.31e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 46678 XM_044317379.1 0 3 0 50 15 Q96AY4 2.39e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 46679 XM_044317379.1 0 3 0 50 15 Q96AY4 8.83e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 46680 XM_044317379.1 0 3 0 50 15 Q96AY4 1.35e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 46681 XM_044317379.1 0 3 0 50 15 Q96AY4 1.47e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 46682 XM_044317379.1 0 3 0 50 15 Q96AY4 3.82e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 46683 XM_044317379.1 0 3 0 50 15 Q96AY4 1.86e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 46684 XM_029357411.2 389 373 315 517 138 Q9Z0U4 2.96e-57 Gamma-aminobutyric acid type B receptor subunit 1 (GABA-B receptor 1) (GABA-B-R1) (GABA-BR1) (GABABR1) (Gb1) Rattus norvegicus (Rat) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; chemical synaptic transmission [GO:0007268]; chemical synaptic transmission, postsynaptic [GO:0099565]; G protein-coupled receptor signaling pathway [GO:0007186]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of dopamine secretion [GO:0033602]; negative regulation of epinephrine secretion [GO:0032811]; negative regulation of gamma-aminobutyric acid secretion [GO:0014053]; negative regulation of synaptic transmission [GO:0050805]; neuron-glial cell signaling [GO:0150099]; osteoblast differentiation [GO:0001649]; positive regulation of glutamate secretion [GO:0014049]; positive regulation of growth hormone secretion [GO:0060124]; regulation of glutamate secretion [GO:0014048]; regulation of postsynaptic membrane potential [GO:0060078]; response to ethanol [GO:0045471]; response to nicotine [GO:0035094]; synaptic transmission, GABAergic [GO:0051932] GO:0001649; GO:0004888; GO:0004965; GO:0005615; GO:0005737; GO:0005789; GO:0005886; GO:0007186; GO:0007193; GO:0007194; GO:0007214; GO:0007268; GO:0008021; GO:0008285; GO:0014048; GO:0014049; GO:0014053; GO:0016020; GO:0030673; GO:0031966; GO:0032811; GO:0033602; GO:0035094; GO:0038037; GO:0038039; GO:0042734; GO:0043005; GO:0043025; GO:0043197; GO:0043198; GO:0043204; GO:0043231; GO:0045121; GO:0045211; GO:0045471; GO:0046982; GO:0050805; GO:0051932; GO:0060078; GO:0060124; GO:0097060; GO:0098685; GO:0098793; GO:0098978; GO:0098982; GO:0099565; GO:0099579; GO:0150047; GO:0150099; GO:1902710; GO:1902712; GO:1990430 46685 XM_029344900.2 15 0 0 36 5 Q5FVH4 9.03e-23 AKT-interacting protein (Fused toes protein homolog) Rattus norvegicus (Rat) apoptotic process [GO:0006915]; early endosome to late endosome transport [GO:0045022]; endosome organization [GO:0007032]; endosome to lysosome transport [GO:0008333]; lysosome organization [GO:0007040]; positive regulation of protein binding [GO:0032092]; positive regulation of protein phosphorylation [GO:0001934]; protein localization to perinuclear region of cytoplasm [GO:1905719]; protein polyubiquitination [GO:0000209]; protein transport [GO:0015031] GO:0000209; GO:0001934; GO:0005634; GO:0005829; GO:0005886; GO:0006915; GO:0007032; GO:0007040; GO:0008333; GO:0015031; GO:0032092; GO:0045022; GO:0061631; GO:0070695; GO:1905719 46686 XM_029341664.2 784 435 250 515 838 NA NA NA NA NA NA 46687 XM_044316969.1 656 631 587 1065 1295 Q96K80 2.36e-31 Zinc finger CCCH domain-containing protein 10 Homo sapiens (Human) negative regulation of miRNA maturation [GO:1903799]; post-transcriptional regulation of gene expression [GO:0010608]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381] GO:0000381; GO:0003723; GO:0005654; GO:0005737; GO:0010608; GO:0035198; GO:0046872; GO:1903799 46688 XM_029353430.2 184 116 121 80 351 NA NA NA NA NA NA 46689 XM_029344450.2 102 5 12 20 0 Q8N865 1.11e-43 Uncharacterized protein C7orf31 Homo sapiens (Human) NA GO:0005737; GO:0005813 46690 XM_029357487.2 0 0 0 16 0 NA NA NA NA NA NA 46691 XR_006397127.1 0 2 4 4 7 NA NA NA NA NA NA 46692 XM_044328037.1 1117 547 673 715 730 Q0VFT9 1.19e-147 Trafficking protein particle complex subunit 13 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA NA 46693 XM_029357687.2 1907 2045 1864 2346 2669 NA NA NA NA NA NA 46694 XM_044314017.1 232 87 253 297 295 A6NE52 9.02e-70 WD repeat-containing protein 97 Homo sapiens (Human) NA NA 46695 XM_044309474.1 93 0 0 149 164 Q91398 1.82e-70 Casein kinase II subunit beta (CK II beta) Danio rerio (Zebrafish) (Brachydanio rerio) regulation of protein serine/threonine phosphatase activity [GO:0080163]; Wnt signaling pathway [GO:0016055] GO:0005737; GO:0005956; GO:0016055; GO:0019887; GO:0046872; GO:0080163 46696 XM_029331528.2 195 180 143 70 95 F1NPQ2 1.21e-55 Multiple inositol polyphosphate phosphatase 1 (EC 3.1.3.62) (2,3-bisphosphoglycerate 3-phosphatase) (2,3-BPG phosphatase) (EC 3.1.3.80) (Band 17) (Histidine phosphatase of the endoplasmic reticulum 1) (HiPER1) Gallus gallus (Chicken) NA GO:0003993; GO:0005788; GO:0034417; GO:0052745; GO:0052826 46697 XM_029356775.2 43 216 96 109 88 Q3B7L6 7.82e-50 Serine/arginine-rich splicing factor 6 (Splicing factor, arginine/serine-rich 6) Bos taurus (Bovine) alternative mRNA splicing, via spliceosome [GO:0000380]; mRNA splice site selection [GO:0006376]; negative regulation of keratinocyte differentiation [GO:0045617]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of keratinocyte proliferation [GO:0010837]; regulation of wound healing [GO:0061041] GO:0000380; GO:0000381; GO:0003723; GO:0006376; GO:0010837; GO:0016607; GO:0036002; GO:0045617; GO:0048025; GO:0061041 46698 XM_044315384.1 0 1 10 5 0 NA NA NA NA NA NA 46699 XM_044316097.1 6 4 4 15 10 NA NA NA NA NA NA 46700 XR_006398068.1 6 4 14 0 20 NA NA NA NA NA NA 46701 XM_029325833.2 5419 6114 2684 3657 2422 Q9UBI1 1.66e-50 COMM domain-containing protein 3 (Protein Bup) (Protein PIL) Homo sapiens (Human) sodium ion transport [GO:0006814] GO:0005576; GO:0005634; GO:0006814; GO:1904813 46702 XM_044318740.1 32 36 43 83 25 Q8C0R9 3.33e-35 Leucine-rich repeat and death domain-containing protein 1 Mus musculus (Mouse) positive regulation of Ras protein signal transduction [GO:0046579]; signal transduction [GO:0007165] GO:0007165; GO:0046579 46703 XM_044318740.1 32 36 43 83 25 Q8C0R9 1.14e-33 Leucine-rich repeat and death domain-containing protein 1 Mus musculus (Mouse) positive regulation of Ras protein signal transduction [GO:0046579]; signal transduction [GO:0007165] GO:0007165; GO:0046579 46704 XM_044318740.1 32 36 43 83 25 Q8C0R9 1.88e-29 Leucine-rich repeat and death domain-containing protein 1 Mus musculus (Mouse) positive regulation of Ras protein signal transduction [GO:0046579]; signal transduction [GO:0007165] GO:0007165; GO:0046579 46705 XM_044318740.1 32 36 43 83 25 Q8C0R9 1.29e-28 Leucine-rich repeat and death domain-containing protein 1 Mus musculus (Mouse) positive regulation of Ras protein signal transduction [GO:0046579]; signal transduction [GO:0007165] GO:0007165; GO:0046579 46706 XM_044318740.1 32 36 43 83 25 Q8C0R9 3.57e-27 Leucine-rich repeat and death domain-containing protein 1 Mus musculus (Mouse) positive regulation of Ras protein signal transduction [GO:0046579]; signal transduction [GO:0007165] GO:0007165; GO:0046579 46707 XM_029333439.2 175 121 137 358 114 Q99JG3 7.37e-25 Annexin A13 (Annexin XIII) (Annexin-13) Mus musculus (Mouse) NA GO:0001786; GO:0005509; GO:0005544; GO:0005654; GO:0005737; GO:0005886; GO:0016324; GO:0019898; GO:0031410; GO:1901611 46708 XM_044313448.1 11 3033 3 6 6 NA NA NA NA NA NA 46709 XM_044327582.1 1 14 8 0 0 NA NA NA NA NA NA 46710 XM_044323261.1 183 3 8 147 27 Q9JM13 4.85e-95 Rab5 GDP/GTP exchange factor (Rabex-5) Mus musculus (Mouse) dendritic transport [GO:0098935]; establishment of localization in cell [GO:0051649]; Kit signaling pathway [GO:0038109]; mast cell degranulation [GO:0043303]; mast cell migration [GO:0097531]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of Kit signaling pathway [GO:1900235]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of mast cell activation [GO:0033004]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; negative regulation of receptor-mediated endocytosis [GO:0048261]; protein phosphorylation [GO:0006468]; protein targeting to membrane [GO:0006612]; Ras protein signal transduction [GO:0007265]; receptor-mediated endocytosis [GO:0006898]; regulation of Fc receptor mediated stimulatory signaling pathway [GO:0060368] GO:0001933; GO:0002686; GO:0003677; GO:0005085; GO:0005730; GO:0005769; GO:0005829; GO:0006468; GO:0006612; GO:0006898; GO:0007265; GO:0008270; GO:0030139; GO:0030425; GO:0031267; GO:0031982; GO:0032715; GO:0032764; GO:0033004; GO:0038109; GO:0043303; GO:0043305; GO:0046580; GO:0048261; GO:0050728; GO:0051649; GO:0055037; GO:0060368; GO:0061630; GO:0097531; GO:0098935; GO:1900235 46711 XM_029338857.2 7013 7606 4102 7403 6488 Q8BPB0 1.89e-137 MOB kinase activator 1B (Mob1 homolog 1A) (Mps one binder kinase activator-like 1A) Mus musculus (Mouse) hippo signaling [GO:0035329]; positive regulation of protein phosphorylation [GO:0001934]; regulation of protein autophosphorylation [GO:0031952]; signal transduction [GO:0007165] GO:0001934; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0007165; GO:0019209; GO:0019900; GO:0030295; GO:0031952; GO:0035329; GO:0046872 46712 XM_044321174.1 1899 1166 1186 2573 1850 Q96PE2 5.08e-124 Rho guanine nucleotide exchange factor 17 (164 kDa Rho-specific guanine-nucleotide exchange factor) (p164-RhoGEF) (p164RhoGEF) (Tumor endothelial marker 4) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; regulation of small GTPase mediated signal transduction [GO:0051056] GO:0005085; GO:0005829; GO:0030036; GO:0051056 46713 XM_044321680.1 95 82 104 122 142 B8V7Q1 2.04e-125 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 46714 XM_029354580.2 14 0 59 53 43 P0CT40 1.46e-75 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 46715 XM_029325817.2 19 28 27 22 31 NA NA NA NA NA NA 46716 XM_029348713.2 25 66 11 86 28 B0UY98 7.2e-23 NA NA NA NA 46717 XM_029337700.2 0 90 182 568 0 O60235 2.14e-52 Transmembrane protease serine 11D (EC 3.4.21.-) (Airway trypsin-like protease) [Cleaved into: Transmembrane protease serine 11D non-catalytic chain; Transmembrane protease serine 11D catalytic chain] Homo sapiens (Human) proteolysis [GO:0006508]; respiratory gaseous exchange by respiratory system [GO:0007585] GO:0004252; GO:0005576; GO:0005886; GO:0006508; GO:0007585; GO:0008233; GO:0070062 46718 XM_044320302.1 0 54 0 0 25 NA NA NA NA NA NA 46719 XM_044309462.1 3 0 8 0 0 O00602 1.74e-79 Ficolin-1 (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin-alpha) (M-ficolin) Homo sapiens (Human) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation, lectin pathway [GO:0001867]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of viral entry into host cell [GO:0046597]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of opsonization [GO:1903028]; protein localization to cell surface [GO:0034394]; proteolysis [GO:0006508]; recognition of apoptotic cell [GO:0043654] GO:0001664; GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005576; GO:0005581; GO:0005615; GO:0006508; GO:0007186; GO:0009897; GO:0030246; GO:0031232; GO:0032757; GO:0033691; GO:0034394; GO:0034774; GO:0038187; GO:0043654; GO:0046597; GO:0046872; GO:0062023; GO:0097367; GO:1903028; GO:1904813; GO:1905370 46720 XM_044311133.1 788 460 555 264 649 NA NA NA NA NA NA 46721 XM_044326856.1 82 89 13 87 115 NA NA NA NA NA NA 46722 XM_044308395.1 76 99 18 107 56 Q5RFE6 5.76e-162 Threonine synthase-like 2 (TSH2) (EC 4.2.3.-) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0016829 46723 XM_029329528.2 1154 1810 1731 1124 1037 NA NA NA NA NA NA 46724 XM_044322272.1 0 6 0 10 2 NA NA NA NA NA NA 46725 XM_044315561.1 243 661 77 203 580 NA NA NA NA NA NA 46726 XM_029323740.2 3887 2604 2814 3275 2602 Q5U3U0 1.3e-102 Phytanoyl-CoA dioxygenase domain-containing protein 1 (Protein PHYHD1) (EC 1.14.11.-) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0046872; GO:0051213 46727 XM_029329027.2 11 0 0 0 0 NA NA NA NA NA NA 46728 XM_044329019.1 723 443 304 420 574 Q4V8C9 7.43e-62 Leucine-rich repeat-containing protein 56 Rattus norvegicus (Rat) cell projection organization [GO:0030030] GO:0005929; GO:0030030 46729 XR_006395074.1 2192 1705 770 1507 555 O18994 6.1e-43 Epididymal secretory glutathione peroxidase (EC 1.11.1.9) (Epididymis-specific glutathione peroxidase-like protein) (EGLP) (Glutathione peroxidase 5) (GPx-5) (GSHPx-5) Sus scrofa (Pig) response to oxidative stress [GO:0006979] GO:0004601; GO:0004602; GO:0005576; GO:0006979 46730 XM_044327827.1 0 0 0 52 0 NA NA NA NA NA NA 46731 XM_044320158.1 76 174 0 40 68 NA NA NA NA NA NA 46732 XM_044308270.1 333 529 302 201 69 NA NA NA NA NA NA 46733 XR_003823751.2 847 497 166 688 622 NA NA NA NA NA NA 46734 XM_044319391.1 53 74 11 47 79 NA NA NA NA NA NA 46735 XM_029333344.2 0 0 390 0 103 Q8WVS4 1.04e-114 Cytoplasmic dynein 2 intermediate chain 1 (Dynein 2 intermediate chain 1) (WD repeat-containing protein 60) Homo sapiens (Human) cilium assembly [GO:0060271]; embryonic skeletal system morphogenesis [GO:0048704]; intraciliary retrograde transport [GO:0035721]; intraciliary transport [GO:0042073]; microtubule-based movement [GO:0007018] GO:0000242; GO:0005615; GO:0005813; GO:0005868; GO:0005929; GO:0007018; GO:0035721; GO:0042073; GO:0045503; GO:0045504; GO:0048704; GO:0060271; GO:0097014; GO:0097542; GO:0097546 46736 XM_044324512.1 0 2 121 62 32 NA NA NA NA NA NA 46737 XM_029329530.2 492 686 546 503 533 Q96MH6 3.68e-91 Transmembrane protein 68 Homo sapiens (Human) NA GO:0016020; GO:0016746 46738 XM_044323059.1 1365 473 435 592 198 NA NA NA NA NA NA 46739 XM_044311751.1 238 162 89 118 42 A8WG43 6.27e-46 Coiled-coil domain-containing protein 89 (Bc8 orange-interacting protein) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005634; GO:0005737 46740 XM_044317865.1 13 4 2 27 43 Q96CG8 3.09e-45 Collagen triple helix repeat-containing protein 1 Homo sapiens (Human) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005576; GO:0005581; GO:0005615; GO:0016477; GO:0016528; GO:0017147; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0062023; GO:0090090; GO:0090103; GO:0090177 46741 XM_029337941.2 5 1 8 5 30 NA NA NA NA NA NA 46742 XM_044318738.1 0 0 9 0 0 NA NA NA NA NA NA 46743 XM_029346906.2 631 744 332 636 374 Q5VU57 0 Cytosolic carboxypeptidase 6 (EC 3.4.17.24) (ATP/GTP-binding protein-like 4) (Protein deglutamylase CCP6) Homo sapiens (Human) anterograde axonal transport of mitochondrion [GO:0098957]; C-terminal protein deglutamylation [GO:0035609]; central nervous system neuron development [GO:0021954]; defense response to virus [GO:0051607]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein deglutamylation [GO:0035608]; protein side chain deglutamylation [GO:0035610]; proteolysis [GO:0006508]; regulation of blastocyst development [GO:0120222]; retrograde axonal transport of mitochondrion [GO:0098958] GO:0004181; GO:0005794; GO:0005814; GO:0005829; GO:0006508; GO:0008270; GO:0008285; GO:0015631; GO:0021954; GO:0035608; GO:0035609; GO:0035610; GO:0036064; GO:0051607; GO:0098957; GO:0098958; GO:0120222; GO:1904115; GO:2000060 46744 XM_029346397.2 0 0 27 0 0 Q8BYM7 3.51e-144 Radial spoke head protein 4 homolog A (Radial spoke head-like protein 3) Mus musculus (Mouse) axoneme assembly [GO:0035082]; cilium movement [GO:0003341]; cilium movement involved in cell motility [GO:0060294]; maintenance of ciliary planar beating movement pattern [GO:0120221]; radial spoke assembly [GO:0062177] GO:0001534; GO:0001535; GO:0003341; GO:0005654; GO:0005730; GO:0005929; GO:0005930; GO:0035082; GO:0060294; GO:0062177; GO:0120221 46745 XM_029338592.2 315 116 148 141 120 O43903 7.85e-63 Growth arrest-specific protein 2 (GAS-2) Homo sapiens (Human) actin crosslink formation [GO:0051764]; antral ovarian follicle growth [GO:0001547]; apoptotic process [GO:0006915]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; initiation of primordial ovarian follicle growth [GO:0001544]; ovulation [GO:0030728]; regulation of cell cycle [GO:0051726]; regulation of cell shape [GO:0008360]; regulation of Notch signaling pathway [GO:0008593] GO:0001544; GO:0001547; GO:0005829; GO:0005884; GO:0006915; GO:0007049; GO:0008017; GO:0008093; GO:0008360; GO:0008593; GO:0016020; GO:0030728; GO:0051015; GO:0051726; GO:0051764; GO:0071711 46746 XM_029348640.2 138 38 79 59 158 NA NA NA NA NA NA 46747 XR_006397704.1 0 0 2 4 11 NA NA NA NA NA NA 46748 XM_044314745.1 383 358 339 430 56 NA NA NA NA NA NA 46749 XM_044322004.1 73 4 14 34 64 Q5ZIJ0 2.61e-59 BUD13 homolog Gallus gallus (Chicken) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0005634; GO:0005684; GO:0070274; GO:0071005 46750 XR_006394269.1 11 4 43 9 189 NA NA NA NA NA NA 46751 XM_044316829.1 6 12 21 4 4 NA NA NA NA NA NA 46752 XR_006397687.1 423 7 515 0 132 NA NA NA NA NA NA 46753 XM_029323539.2 1810 1742 1065 1549 1543 NA NA NA NA NA NA 46754 XM_029325527.2 28 16 39 25 19 NA NA NA NA NA NA 46755 XR_003825753.2 857 552 664 528 504 Q96MU7 9.56e-59 YTH domain-containing protein 1 (Splicing factor YT521) (YT521-B) Homo sapiens (Human) dosage compensation by inactivation of X chromosome [GO:0009048]; in utero embryonic development [GO:0001701]; mRNA alternative polyadenylation [GO:0110104]; mRNA export from nucleus [GO:0006406]; mRNA splice site selection [GO:0006376]; mRNA splicing, via spliceosome [GO:0000398]; post-transcriptional regulation of gene expression [GO:0010608]; primary follicle stage [GO:0048160]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of mRNA splicing, via spliceosome [GO:0048024]; spermatogenesis [GO:0007283] GO:0000381; GO:0000398; GO:0001701; GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0005886; GO:0006376; GO:0006406; GO:0007283; GO:0009048; GO:0010608; GO:0016607; GO:0048024; GO:0048160; GO:0110104; GO:1990247 46756 XR_006394549.1 5 3 34 47 8 NA NA NA NA NA NA 46757 XM_029348965.2 1211 981 550 859 793 Q02370 1.86e-34 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (Complex I-B8) (CI-B8) (NADH-ubiquinone oxidoreductase B8 subunit) Bos taurus (Bovine) mitochondrial respiratory chain complex I assembly [GO:0032981] GO:0005747; GO:0031966; GO:0032981 46758 XM_029358487.2 1271 811 553 1081 933 Q8K2G4 0 Bardet-Biedl syndrome 7 protein homolog (BBS2-like protein 1) Mus musculus (Mouse) brain development [GO:0007420]; cilium assembly [GO:0060271]; eye development [GO:0001654]; fat cell differentiation [GO:0045444]; heart development [GO:0007507]; intracellular transport [GO:0046907]; limb development [GO:0060173]; non-motile cilium assembly [GO:1905515]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; primary palate development [GO:1903929]; protein localization [GO:0008104]; protein transport [GO:0015031]; regulation of transcription by RNA polymerase II [GO:0006357]; smoothened signaling pathway [GO:0007224] GO:0001654; GO:0001750; GO:0005634; GO:0005813; GO:0005930; GO:0006357; GO:0007224; GO:0007420; GO:0007507; GO:0008104; GO:0015031; GO:0016020; GO:0032436; GO:0034464; GO:0036064; GO:0043005; GO:0045444; GO:0046907; GO:0060170; GO:0060173; GO:0060271; GO:0061629; GO:1903929; GO:1905515 46759 XR_006396595.1 148 179 222 285 238 NA NA NA NA NA NA 46760 XM_029337101.2 28 151 101 0 0 Q8TCT0 3.5e-75 Ceramide kinase (hCERK) (EC 2.7.1.138) (Acylsphingosine kinase) (Lipid kinase 4) (LK4) Homo sapiens (Human) ceramide metabolic process [GO:0006672]; glycosphingolipid metabolic process [GO:0006687]; phosphorylation [GO:0016310]; sphingolipid metabolic process [GO:0006665] GO:0000287; GO:0001727; GO:0001729; GO:0005524; GO:0005737; GO:0005886; GO:0006665; GO:0006672; GO:0006687; GO:0016020; GO:0016310; GO:0102773 46761 XM_044312379.1 0 1 42 10 85 NA NA NA NA NA NA 46762 XM_029358435.2 799 761 568 595 548 Q5T280 2.38e-131 Putative methyltransferase C9orf114 (EC 2.1.1.-) (Centromere protein 32) (CENP-32) (Kinetochore-associated protein) (SPOUT domain-containing methyltransferase 1) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; maintenance of centrosome location [GO:0051661]; methylation [GO:0032259]; miRNA processing [GO:0035196]; post-transcriptional regulation of gene expression [GO:0010608] GO:0000776; GO:0003723; GO:0005737; GO:0007049; GO:0008168; GO:0010608; GO:0031616; GO:0032259; GO:0035196; GO:0035198; GO:0051301; GO:0051661; GO:0072686 46763 XR_006395200.1 168 107 110 114 161 NA NA NA NA NA NA 46764 XR_006395470.1 0 5 0 0 8 NA NA NA NA NA NA 46765 XM_044327579.1 10 31 0 0 1 NA NA NA NA NA NA 46766 XM_044313157.1 0 10 17 0 0 A2AJ76 4.77e-72 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 46767 XM_044313157.1 0 10 17 0 0 A2AJ76 1.34e-63 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 46768 XM_044313157.1 0 10 17 0 0 A2AJ76 2.83e-63 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 46769 XM_044313157.1 0 10 17 0 0 A2AJ76 7.25e-62 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 46770 XM_044313157.1 0 10 17 0 0 A2AJ76 2.96e-58 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 46771 XM_044313157.1 0 10 17 0 0 A2AJ76 3.96e-55 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 46772 XM_044313157.1 0 10 17 0 0 A2AJ76 8.47e-50 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 46773 XM_044313157.1 0 10 17 0 0 A2AJ76 9.95e-50 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 46774 XM_044313157.1 0 10 17 0 0 A2AJ76 4.61e-47 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 46775 XM_044313157.1 0 10 17 0 0 A2AJ76 2.35e-46 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 46776 XM_044313157.1 0 10 17 0 0 A2AJ76 2.45e-46 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 46777 XM_044313157.1 0 10 17 0 0 A2AJ76 1.83e-43 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 46778 XM_044313157.1 0 10 17 0 0 A2AJ76 2.32e-43 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 46779 XM_044313157.1 0 10 17 0 0 A2AJ76 2.77e-34 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 46780 XM_044313157.1 0 10 17 0 0 A2AJ76 2.13e-27 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 46781 XM_029340864.2 0 0 22 0 0 O75486 1.41e-50 Transcription initiation protein SPT3 homolog (SPT3-like protein) Homo sapiens (Human) histone acetylation [GO:0016573]; histone H3 acetylation [GO:0043966]; monoubiquitinated histone deubiquitination [GO:0035521]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA repair [GO:0006282]; regulation of DNA-templated transcription [GO:0006355]; regulation of RNA splicing [GO:0043484]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366] GO:0000124; GO:0003713; GO:0005634; GO:0005654; GO:0006282; GO:0006355; GO:0006357; GO:0006366; GO:0016573; GO:0033276; GO:0035521; GO:0035522; GO:0043484; GO:0043966; GO:0045893; GO:0046982 46782 XM_029327847.2 0 0 0 314 73 Q5ZL23 2.56e-66 Amyloid beta A4 precursor protein-binding family B member 1-interacting protein (APBB1-interacting protein 1) Gallus gallus (Chicken) signal transduction [GO:0007165] GO:0005829; GO:0005856; GO:0005886; GO:0007165 46783 XM_029357480.2 66 10 80 22 129 NA NA NA NA NA NA 46784 XM_029342922.2 1445 973 737 1778 1896 Q5R8W6 8.4e-108 Luc7-like protein 3 (Cisplatin resistance-associated-overexpressed protein) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) mRNA splice site selection [GO:0006376]; RNA splicing [GO:0008380] GO:0003677; GO:0003729; GO:0005634; GO:0005685; GO:0006376; GO:0008380; GO:0016607 46785 XM_044309498.1 16 3 7 4 103 NA NA NA NA NA NA 46786 XM_044314557.1 1 0 0 15 1 P35187 7.85e-42 ATP-dependent helicase SGS1 (EC 3.6.4.12) (Helicase TPS1) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) chromosome organization [GO:0051276]; DNA double-strand break processing [GO:0000729]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA topological change [GO:0006265]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724]; gene conversion at mating-type locus [GO:0007534]; meiotic chromosome segregation [GO:0045132]; meiotic DNA double-strand break processing [GO:0000706]; mitotic G2/M transition checkpoint [GO:0044818]; mitotic intra-S DNA damage checkpoint signaling [GO:0031573]; mitotic sister chromatid segregation [GO:0000070]; negative regulation of meiotic joint molecule formation [GO:0010947]; regulation of reciprocal meiotic recombination [GO:0010520]; telomere maintenance [GO:0000723]; telomere maintenance via recombination [GO:0000722]; telomeric 3' overhang formation [GO:0031860] GO:0000070; GO:0000706; GO:0000722; GO:0000723; GO:0000724; GO:0000729; GO:0003676; GO:0005524; GO:0005634; GO:0005694; GO:0005730; GO:0005737; GO:0006265; GO:0006268; GO:0006281; GO:0006310; GO:0007534; GO:0009378; GO:0010520; GO:0010947; GO:0016887; GO:0031422; GO:0031573; GO:0031860; GO:0032508; GO:0043138; GO:0044818; GO:0045132; GO:0051276 46787 XM_044314557.1 1 0 0 15 1 P35187 7.85e-42 ATP-dependent helicase SGS1 (EC 3.6.4.12) (Helicase TPS1) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) chromosome organization [GO:0051276]; DNA double-strand break processing [GO:0000729]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA topological change [GO:0006265]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724]; gene conversion at mating-type locus [GO:0007534]; meiotic chromosome segregation [GO:0045132]; meiotic DNA double-strand break processing [GO:0000706]; mitotic G2/M transition checkpoint [GO:0044818]; mitotic intra-S DNA damage checkpoint signaling [GO:0031573]; mitotic sister chromatid segregation [GO:0000070]; negative regulation of meiotic joint molecule formation [GO:0010947]; regulation of reciprocal meiotic recombination [GO:0010520]; telomere maintenance [GO:0000723]; telomere maintenance via recombination [GO:0000722]; telomeric 3' overhang formation [GO:0031860] GO:0000070; GO:0000706; GO:0000722; GO:0000723; GO:0000724; GO:0000729; GO:0003676; GO:0005524; GO:0005634; GO:0005694; GO:0005730; GO:0005737; GO:0006265; GO:0006268; GO:0006281; GO:0006310; GO:0007534; GO:0009378; GO:0010520; GO:0010947; GO:0016887; GO:0031422; GO:0031573; GO:0031860; GO:0032508; GO:0043138; GO:0044818; GO:0045132; GO:0051276 46788 XR_006396107.1 0 0 31 0 0 NA NA NA NA NA NA 46789 XM_029356204.2 21 0 0 0 19 NA NA NA NA NA NA 46790 XR_003823472.2 28720 24376 8388 14900 8792 NA NA NA NA NA NA 46791 XM_029333300.2 954 1110 845 961 705 Q9D845 2.03e-76 Testis-expressed protein 9 (Testis-specifically expressed protein 1) (Tsec-1) Mus musculus (Mouse) NA GO:0005737; GO:0034451 46792 XM_029342560.2 12605 10444 5535 6801 6799 P17702 8.83e-35 60S ribosomal protein L28 Rattus norvegicus (Rat) translation [GO:0006412] GO:0003735; GO:0006412; GO:0022625; GO:0022626; GO:0030425; GO:0036464; GO:0044297; GO:0045202 46793 XM_044308807.1 351 153 172 26 311 NA NA NA NA NA NA 46794 XM_044323280.1 34 20 47 8 53 NA NA NA NA NA NA 46795 XR_006396935.1 182 78 123 134 194 Q5U374 1.68e-48 Kelch-like protein 12 Danio rerio (Zebrafish) (Brachydanio rerio) anterior/posterior pattern specification [GO:0009952]; convergent extension involved in axis elongation [GO:0060028]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; protein monoubiquitination [GO:0006513]; Wnt signaling pathway [GO:0016055] GO:0006513; GO:0006888; GO:0009952; GO:0014029; GO:0014032; GO:0016055; GO:0030127; GO:0030134; GO:0031463; GO:0048208; GO:0060028 46796 XR_006396935.1 182 78 123 134 194 Q5U374 1.68e-48 Kelch-like protein 12 Danio rerio (Zebrafish) (Brachydanio rerio) anterior/posterior pattern specification [GO:0009952]; convergent extension involved in axis elongation [GO:0060028]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; protein monoubiquitination [GO:0006513]; Wnt signaling pathway [GO:0016055] GO:0006513; GO:0006888; GO:0009952; GO:0014029; GO:0014032; GO:0016055; GO:0030127; GO:0030134; GO:0031463; GO:0048208; GO:0060028 46797 XM_044328263.1 12 2581 271 60 112 NA NA NA NA NA NA 46798 XM_044329170.1 233 108 125 253 204 NA NA NA NA NA NA 46799 XM_029356390.2 10084 8011 5462 8009 8269 Q9DBD2 4.62e-82 E3 ubiquitin-protein ligase MARCHF8 (EC 2.3.2.27) (Cellular modulator of immune recognition) (c-MIR) (Membrane-associated RING finger protein 8) (Membrane-associated RING-CH protein VIII) (MARCH-VIII) (RING-type E3 ubiquitin transferase MARCHF8) Mus musculus (Mouse) adaptive immune response [GO:0002250]; antigen processing and presentation of peptide antigen via MHC class II [GO:0002495]; immune response [GO:0006955]; negative regulation of MHC class II biosynthetic process [GO:0045347]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567] GO:0000209; GO:0002250; GO:0002495; GO:0004842; GO:0005737; GO:0005764; GO:0005765; GO:0005768; GO:0006955; GO:0008270; GO:0016567; GO:0031901; GO:0031902; GO:0042287; GO:0042289; GO:0045347; GO:0061630 46800 XM_044320958.1 31 4 19 50 86 NA NA NA NA NA NA 46801 XM_029329029.2 941 597 541 761 375 Q5T447 0 E3 ubiquitin-protein ligase HECTD3 (EC 2.3.2.26) (HECT domain-containing protein 3) (HECT-type E3 ubiquitin transferase HECTD3) Homo sapiens (Human) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] GO:0004842; GO:0019905; GO:0043161; GO:0048471 46802 XM_044306830.1 1102 1059 519 968 919 NA NA NA NA NA NA 46803 XR_006396938.1 139 199 52 57 61 NA NA NA NA NA NA 46804 XM_044314526.1 1 1 0 14 19 NA NA NA NA NA NA 46805 XM_029344947.2 42 15 0 45 105 Q4G0X4 2.85e-32 BTB/POZ domain-containing protein KCTD21 (KCASH2 protein) (Potassium channel tetramerization domain-containing protein 21) Homo sapiens (Human) negative regulation of smoothened signaling pathway [GO:0045879]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0006511; GO:0016567; GO:0042802; GO:0042826; GO:0045879; GO:0051260; GO:0097602 46806 XM_044318005.1 265 43 14 12 10 NA NA NA NA NA NA 46807 XM_029343451.2 0 0 17 0 0 NA NA NA NA NA NA 46808 XM_029345171.2 780 791 370 717 493 Q3SZV5 9.19e-42 Proteasome maturation protein (Proteassemblin) Bos taurus (Bovine) proteasome assembly [GO:0043248] GO:0005634; GO:0005737; GO:0005783; GO:0005829; GO:0016020; GO:0043248 46809 XM_029338142.2 300 224 294 439 485 NA NA NA NA NA NA 46810 XM_044310714.1 9 0 0 22 0 NA NA NA NA NA NA 46811 XM_029352115.2 1494 1470 543 1167 886 P24666 7.57e-46 Low molecular weight phosphotyrosine protein phosphatase (LMW-PTP) (LMW-PTPase) (EC 3.1.3.48) (Adipocyte acid phosphatase) (Low molecular weight cytosolic acid phosphatase) (EC 3.1.3.2) (Red cell acid phosphatase 1) Homo sapiens (Human) protein dephosphorylation [GO:0006470] GO:0003993; GO:0004725; GO:0004726; GO:0005737; GO:0005829; GO:0006470; GO:0009898; GO:0042383; GO:0070062 46812 XM_029345901.2 24 11 31 42 16 NA NA NA NA NA NA 46813 XM_029340897.2 4329 6272 3089 3692 2875 NA NA NA NA NA NA 46814 XM_044314890.1 26 2 1 0 0 NA NA NA NA NA NA 46815 XR_006394519.1 0 2 33 1 45 NA NA NA NA NA NA 46816 XR_006397183.1 5 0 7 0 14 NA NA NA NA NA NA 46817 XR_006391353.1 2159 1177 770 1054 1113 NA NA NA NA NA NA 46818 XM_029345022.2 4 6 22 0 17 NA NA NA NA NA NA 46819 XM_029344185.2 43 15 5 1 38 NA NA NA NA NA NA 46820 XR_006392268.1 10 21 7 11 131 NA NA NA NA NA NA 46821 XR_006396215.1 1 1 9 6 3 NA NA NA NA NA NA 46822 XM_044322743.1 0 8 0 5 7 NA NA NA NA NA NA 46823 XM_044310910.1 21 39 2 12 21 Q5DU56 3.41e-28 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 46824 XM_044310910.1 21 39 2 12 21 Q5DU56 7.84e-25 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 46825 XR_006394617.1 14 0 30 0 20 NA NA NA NA NA NA 46826 XR_006397805.1 20 38 1 82 218 NA NA NA NA NA NA 46827 XM_029335647.2 0 151 0 51 101 Q8K4R9 9.09e-29 Disks large-associated protein 5 (DAP-5) (Discs large homolog 7) (Disks large-associated protein DLG7) (Hepatoma up-regulated protein homolog) (HURP) Mus musculus (Mouse) centrosome localization [GO:0051642]; chromosome segregation [GO:0007059]; kinetochore assembly [GO:0051382]; mitotic spindle organization [GO:0007052]; regulation of mitotic cell cycle [GO:0007346]; signaling [GO:0023052] GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0007052; GO:0007059; GO:0007346; GO:0008017; GO:0023052; GO:0031616; GO:0034451; GO:0051382; GO:0051642 46828 XM_029347227.2 71 56 136 49 168 NA NA NA NA NA NA 46829 XM_029327589.2 0 0 0 27 153 NA NA NA NA NA NA 46830 XM_044311618.1 2 0 26 0 1 NA NA NA NA NA NA 46831 XM_044313681.1 48 0 10 17 12 NA NA NA NA NA NA 46832 XM_029357442.2 0 0 0 5 146 Q9QUM7 0 MutS protein homolog 5 Mus musculus (Mouse) chiasma assembly [GO:0051026]; female gamete generation [GO:0007292]; homologous chromosome pairing at meiosis [GO:0007129]; meiosis I [GO:0007127]; mismatch repair [GO:0006298] GO:0000795; GO:0003690; GO:0005524; GO:0005634; GO:0005654; GO:0006298; GO:0007127; GO:0007129; GO:0007292; GO:0030983; GO:0051026; GO:0140664 46833 XM_044320373.1 10 1 1 1 19 NA NA NA NA NA NA 46834 XM_044327246.1 856 453 246 347 298 Q9UBD5 0 Origin recognition complex subunit 3 (Origin recognition complex subunit Latheo) Homo sapiens (Human) DNA replication [GO:0006260]; DNA replication initiation [GO:0006270]; glial cell proliferation [GO:0014009]; neural precursor cell proliferation [GO:0061351]; regulation of DNA replication [GO:0006275] GO:0000781; GO:0000785; GO:0000808; GO:0003688; GO:0005654; GO:0005656; GO:0005664; GO:0006260; GO:0006270; GO:0006275; GO:0014009; GO:0016604; GO:0031261; GO:0061351 46835 XM_029333975.2 1283 673 560 1394 871 Q6QT07 3.43e-119 Carotenoid-cleaving dioxygenase, mitochondrial (EC 1.13.11.-) (EC 1.13.11.71) (Beta,beta-carotene 9',10'-oxygenase) Mustela putorius furo (European domestic ferret) (Mustela furo) carotene catabolic process [GO:0016121]; lutein catabolic process [GO:0062172]; lycopene catabolic process [GO:1901176]; xanthophyll catabolic process [GO:0016124]; zeaxanthin catabolic process [GO:1901826] GO:0004497; GO:0005739; GO:0010437; GO:0016121; GO:0016124; GO:0046872; GO:0062172; GO:0102076; GO:1901176; GO:1901826 46836 XR_006392193.1 6 11 13 4 21 NA NA NA NA NA NA 46837 XM_029343350.2 3289 2112 1690 3068 2756 P17713 0 Tyrosine-protein kinase STK (EC 2.7.10.2) (P57-STK) Hydra vulgaris (Hydra) (Hydra attenuata) NA GO:0004715; GO:0005524 46838 XR_003822870.2 202 100 41 59 39 NA NA NA NA NA NA 46839 XM_029333731.2 101 0 103 2 0 Q5U3G6 1.7e-102 Protein YIF1B (YIP1-interacting factor homolog B) Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; protein transport [GO:0015031]; sperm flagellum assembly [GO:0120316] GO:0000139; GO:0005783; GO:0005789; GO:0005793; GO:0005794; GO:0006888; GO:0015031; GO:0030134; GO:0033116; GO:0060271; GO:0120316 46840 XM_029352313.2 142 111 102 126 102 Q9JIQ8 1.84e-55 Transmembrane protease serine 2 (EC 3.4.21.-) (Epitheliasin) (Plasmic transmembrane protein X) [Cleaved into: Transmembrane protease serine 2 non-catalytic chain; Transmembrane protease serine 2 catalytic chain] Mus musculus (Mouse) positive regulation of viral entry into host cell [GO:0046598]; protein autoprocessing [GO:0016540]; proteolysis [GO:0006508] GO:0004252; GO:0005044; GO:0005576; GO:0005654; GO:0005886; GO:0006508; GO:0016540; GO:0046598 46841 XM_044316913.1 799 292 345 624 422 Q6DIR8 0 Paladin Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005829 46842 XM_029326370.2 71 30 187 302 96 NA NA NA NA NA NA 46843 XM_029348611.2 74 7 67 26 295 NA NA NA NA NA NA 46844 XM_044319118.1 27 20 1 27 0 NA NA NA NA NA NA 46845 XM_029326410.2 58 1 65 20 146 NA NA NA NA NA NA 46846 XM_044313140.1 0 0 122 0 223 A2AJ76 2.97e-71 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 46847 XM_044313140.1 0 0 122 0 223 A2AJ76 2.63e-63 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 46848 XM_044313140.1 0 0 122 0 223 A2AJ76 5.59e-63 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 46849 XM_044313140.1 0 0 122 0 223 A2AJ76 1.75e-62 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 46850 XM_044313140.1 0 0 122 0 223 A2AJ76 6.4e-59 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 46851 XM_044313140.1 0 0 122 0 223 A2AJ76 2.71e-58 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 46852 XM_044313140.1 0 0 122 0 223 A2AJ76 1.5e-54 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 46853 XM_044313140.1 0 0 122 0 223 A2AJ76 2.39e-52 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 46854 XM_044313140.1 0 0 122 0 223 A2AJ76 2.29e-51 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 46855 XM_044313140.1 0 0 122 0 223 A2AJ76 4.81e-50 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 46856 XM_044313140.1 0 0 122 0 223 A2AJ76 4.24e-49 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 46857 XM_044313140.1 0 0 122 0 223 A2AJ76 2.53e-46 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 46858 XM_044313140.1 0 0 122 0 223 A2AJ76 1.36e-45 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 46859 XM_044313140.1 0 0 122 0 223 A2AJ76 1.29e-44 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 46860 XM_044313140.1 0 0 122 0 223 A2AJ76 4.77e-44 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 46861 XM_044313140.1 0 0 122 0 223 A2AJ76 9.76e-44 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 46862 XM_044313140.1 0 0 122 0 223 A2AJ76 4.69e-27 Hemicentin-2 Mus musculus (Mouse) response to stimulus [GO:0050896] GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005938; GO:0030054; GO:0031012; GO:0032154; GO:0050896; GO:0062023 46863 XM_044329033.1 869 525 494 777 821 F1LQX4 5.98e-113 Rho GTPase-activating protein 44 (Rho-type GTPase-activating protein RICH2) (RhoGAP interacting with CIP4 homologs protein 2) (RICH-2) Rattus norvegicus (Rat) exocytosis [GO:0006887]; modification of dendritic spine [GO:0098886]; modification of postsynaptic structure [GO:0099010]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of filopodium assembly [GO:0051490]; negative regulation of Rac protein signal transduction [GO:0035021]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of GTPase activity [GO:0043087]; regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0099152]; regulation of Rac protein signal transduction [GO:0035020]; signal transduction [GO:0007165] GO:0005096; GO:0005543; GO:0006887; GO:0007165; GO:0014069; GO:0030425; GO:0031256; GO:0031267; GO:0032956; GO:0035020; GO:0035021; GO:0043087; GO:0043197; GO:0048786; GO:0050804; GO:0051490; GO:0055037; GO:0061001; GO:0098886; GO:0098887; GO:0098978; GO:0099010; GO:0099152 46864 XM_044313437.1 0 0 0 20 0 NA NA NA NA NA NA 46865 XM_029341037.2 559 1169 503 454 384 P22676 1.07e-27 Calretinin (CR) (29 kDa calbindin) Homo sapiens (Human) regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of long-term synaptic potentiation [GO:1900271]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509] GO:0005509; GO:0005634; GO:0005829; GO:0005921; GO:0030425; GO:0043005; GO:0043195; GO:0045202; GO:0051480; GO:0098688; GO:0099509; GO:0099534; GO:1900271 46866 XM_044311780.1 74 45 77 160 50 NA NA NA NA NA NA 46867 XM_029353725.2 80 118 78 41 161 O57422 4.77e-30 Melanopsin-B (Opsin-4B) (xMOP) Xenopus laevis (African clawed frog) phototransduction [GO:0007602]; visual perception [GO:0007601] GO:0004930; GO:0005886; GO:0007601; GO:0007602; GO:0009881 46868 XM_044308086.1 0 0 12 0 162 Q92113 7.29e-136 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Squalus acanthias (Spiny dogfish) steroid biosynthetic process [GO:0006694] GO:0004508; GO:0005506; GO:0006694; GO:0016020; GO:0020037; GO:0047442 46869 XM_029323847.2 0 0 0 13 0 Q566X8 8.03e-31 Diencephalon/mesencephalon homeobox protein 1-B Danio rerio (Zebrafish) (Brachydanio rerio) midbrain development [GO:0030901]; regulation of cell cycle [GO:0051726]; regulation of mitotic cell cycle [GO:0007346]; regulation of neural retina development [GO:0061074]; regulation of neurogenesis [GO:0050767]; regulation of transcription by RNA polymerase II [GO:0006357]; retina development in camera-type eye [GO:0060041] GO:0000977; GO:0000981; GO:0005634; GO:0006357; GO:0007346; GO:0030901; GO:0050767; GO:0051726; GO:0060041; GO:0061074 46870 XR_006395630.1 36 15 10 22 39 NA NA NA NA NA NA 46871 XM_029350183.2 454 195 111 320 335 NA NA NA NA NA NA 46872 XM_044316966.1 37 24 2 31 37 NA NA NA NA NA NA 46873 XM_029357873.2 904 418 492 738 946 Q92636 0 Protein FAN (Factor associated with neutral sphingomyelinase activation) (Factor associated with N-SMase activation) Homo sapiens (Human) ceramide metabolic process [GO:0006672]; positive regulation of apoptotic process [GO:0043065]; signal transduction [GO:0007165] GO:0005737; GO:0005829; GO:0006672; GO:0007165; GO:0016230; GO:0043065 46874 XM_044321125.1 0 1 0 10 0 Q96DM1 3.51e-55 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 46875 XM_044321125.1 0 1 0 10 0 Q96DM1 3.51e-55 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 46876 XM_029331883.2 2294 2453 1370 3577 5776 B2RVL6 6.78e-69 Zinc finger CCHC domain-containing protein 24 Mus musculus (Mouse) NA GO:0003676; GO:0008270 46877 XM_044313317.1 11 8 3 35 43 P51169 1.34e-40 Amiloride-sensitive sodium channel subunit beta (Beta-NaCH) (Epithelial Na(+) channel subunit beta) (Beta-ENaC) (Nonvoltage-gated sodium channel 1 subunit beta) (SCNEB) Xenopus laevis (African clawed frog) multicellular organismal water homeostasis [GO:0050891]; sodium ion homeostasis [GO:0055078]; sodium ion transmembrane transport [GO:0035725] GO:0005886; GO:0015280; GO:0016324; GO:0030659; GO:0034706; GO:0035725; GO:0050891; GO:0055078 46878 XM_044320556.1 207 42 57 369 166 B8V7S0 1.32e-179 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 46879 XM_044320556.1 207 42 57 369 166 B8V7S0 1.24e-40 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 46880 XM_044320556.1 207 42 57 369 166 B8V7S0 1.57e-29 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 46881 XM_044327121.1 482 259 253 555 325 NA NA NA NA NA NA 46882 XM_029344999.2 129 71 22 164 174 NA NA NA NA NA NA 46883 XM_044325066.1 45 47 1 72 58 NA NA NA NA NA NA 46884 XM_029356246.2 0 0 1414 0 656 Q5F383 5.9e-112 Signal peptide peptidase-like 2B (SPP-like 2B) (SPPL2b) (EC 3.4.23.-) Gallus gallus (Chicken) membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; membrane protein proteolysis [GO:0033619]; regulation of immune response [GO:0050776] GO:0000139; GO:0005765; GO:0005886; GO:0006509; GO:0010008; GO:0030660; GO:0031293; GO:0033619; GO:0042500; GO:0042803; GO:0050776; GO:0098553; GO:0098554 46885 XM_044315630.1 17 0 1 60 0 NA NA NA NA NA NA 46886 XM_044317125.1 218 0 0 27 29 NA NA NA NA NA NA 46887 XR_006395410.1 0 214 6 0 1 NA NA NA NA NA NA 46888 XM_029334818.2 48 38 25 0 0 NA NA NA NA NA NA 46889 XM_029337593.2 0 0 0 94 0 Q7Z2Z2 0 Elongation factor-like GTPase 1 (Elongation factor Tu GTP-binding domain-containing protein 1) (Elongation factor-like 1) (Protein FAM42A) Homo sapiens (Human) cytosolic ribosome assembly [GO:0042256]; GTP metabolic process [GO:0046039] GO:0003746; GO:0003924; GO:0005525; GO:0042256; GO:0043022; GO:0046039; GO:1990904 46890 XR_003824488.2 6 18 9 24 14 NA NA NA NA NA NA 46891 XM_044310692.1 0 0 101 24 9 A3KMX0 0 DNA excision repair protein ERCC-6-like 2 (EC 3.6.4.-) Bos taurus (Bovine) DNA repair [GO:0006281] GO:0003677; GO:0004386; GO:0005524; GO:0005634; GO:0005739; GO:0005815; GO:0006281; GO:0016787; GO:0140658 46892 XM_044310692.1 0 0 101 24 9 A3KMX0 1.43e-21 DNA excision repair protein ERCC-6-like 2 (EC 3.6.4.-) Bos taurus (Bovine) DNA repair [GO:0006281] GO:0003677; GO:0004386; GO:0005524; GO:0005634; GO:0005739; GO:0005815; GO:0006281; GO:0016787; GO:0140658 46893 XM_044317516.1 1591 1381 1118 2167 2351 P58022 4.51e-153 Lysyl oxidase homolog 2 (EC 1.4.3.13) (Lysyl oxidase-like protein 2) Mus musculus (Mouse) collagen fibril organization [GO:0030199]; endothelial cell migration [GO:0043542]; endothelial cell proliferation [GO:0001935]; epithelial to mesenchymal transition [GO:0001837]; heterochromatin organization [GO:0070828]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of stem cell population maintenance [GO:1902455]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-lysine oxidation [GO:0018057]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; protein modification process [GO:0036211]; response to copper ion [GO:0046688]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040] GO:0000122; GO:0000785; GO:0001666; GO:0001837; GO:0001935; GO:0002040; GO:0004720; GO:0005044; GO:0005507; GO:0005509; GO:0005604; GO:0005615; GO:0005634; GO:0005654; GO:0005783; GO:0010718; GO:0016020; GO:0018057; GO:0030199; GO:0032332; GO:0036211; GO:0043542; GO:0045892; GO:0046688; GO:0062023; GO:0070492; GO:0070828; GO:1902455 46894 XM_044317516.1 1591 1381 1118 2167 2351 P58022 8.12e-147 Lysyl oxidase homolog 2 (EC 1.4.3.13) (Lysyl oxidase-like protein 2) Mus musculus (Mouse) collagen fibril organization [GO:0030199]; endothelial cell migration [GO:0043542]; endothelial cell proliferation [GO:0001935]; epithelial to mesenchymal transition [GO:0001837]; heterochromatin organization [GO:0070828]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of stem cell population maintenance [GO:1902455]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-lysine oxidation [GO:0018057]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; protein modification process [GO:0036211]; response to copper ion [GO:0046688]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040] GO:0000122; GO:0000785; GO:0001666; GO:0001837; GO:0001935; GO:0002040; GO:0004720; GO:0005044; GO:0005507; GO:0005509; GO:0005604; GO:0005615; GO:0005634; GO:0005654; GO:0005783; GO:0010718; GO:0016020; GO:0018057; GO:0030199; GO:0032332; GO:0036211; GO:0043542; GO:0045892; GO:0046688; GO:0062023; GO:0070492; GO:0070828; GO:1902455 46895 XR_006395962.1 102 2 90 48 0 NA NA NA NA NA NA 46896 XR_006394774.1 1 0 2 3 7 NA NA NA NA NA NA 46897 XM_029348729.2 178 62 144 105 474 Q9SAL0 6.16e-78 E3 ubiquitin-protein ligase RGLG4 (EC 2.3.2.27) (RING domain ligase 4) Arabidopsis thaliana (Mouse-ear cress) defense response to bacterium [GO:0042742]; jasmonic acid mediated signaling pathway [GO:0009867]; protein K63-linked ubiquitination [GO:0070534]; response to wounding [GO:0009611] GO:0004842; GO:0005634; GO:0005737; GO:0005739; GO:0009611; GO:0009867; GO:0042742; GO:0046872; GO:0061630; GO:0070534 46898 XM_044317807.1 29 0 166 8 0 Q5U4U5 4.46e-36 Mitochondrial import inner membrane translocase subunit Tim22 Xenopus laevis (African clawed frog) protein insertion into mitochondrial inner membrane [GO:0045039] GO:0042721; GO:0045039 46899 XR_006397311.1 80 48 39 70 33 Q6DIV6 3.56e-50 Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Solute carrier family 32 member 1) (Vesicular GABA transporter) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) beta-alanine transport [GO:0001762]; gamma-aminobutyric acid import [GO:0051939]; gamma-aminobutyric acid transport [GO:0015812]; glycine transport [GO:0015816]; neurotransmitter transport [GO:0006836] GO:0001762; GO:0006836; GO:0008021; GO:0015185; GO:0015187; GO:0015812; GO:0015816; GO:0030659; GO:0042995; GO:0051939; GO:0098793; GO:0140799; GO:0140800 46900 XR_006397311.1 80 48 39 70 33 Q6DIV6 3.56e-50 Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Solute carrier family 32 member 1) (Vesicular GABA transporter) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) beta-alanine transport [GO:0001762]; gamma-aminobutyric acid import [GO:0051939]; gamma-aminobutyric acid transport [GO:0015812]; glycine transport [GO:0015816]; neurotransmitter transport [GO:0006836] GO:0001762; GO:0006836; GO:0008021; GO:0015185; GO:0015187; GO:0015812; GO:0015816; GO:0030659; GO:0042995; GO:0051939; GO:0098793; GO:0140799; GO:0140800 46901 XM_029330264.2 141 50 23 143 325 NA NA NA NA NA NA 46902 XR_006393097.1 0 28 10 9 8 NA NA NA NA NA NA 46903 XM_044308981.1 65 46 10 105 158 NA NA NA NA NA NA 46904 XM_029350219.2 399 959 307 726 609 Q9R0Z9 8.46e-161 Rho GTPase-activating protein 7 (Deleted in liver cancer 1 protein homolog) (DLC-1) (Rho-type GTPase-activating protein 7) (START domain-containing protein 12) (StARD12) (StAR-related lipid transfer protein 12) Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of phospholipase C activity [GO:0007202]; apoptotic process [GO:0006915]; cytoskeleton organization [GO:0007010]; focal adhesion assembly [GO:0048041]; forebrain development [GO:0030900]; heart morphogenesis [GO:0003007]; hindbrain morphogenesis [GO:0021575]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of stress fiber assembly [GO:0051497]; neural tube closure [GO:0001843]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; regulation of Rho protein signal transduction [GO:0035023]; signal transduction [GO:0007165] GO:0001725; GO:0001843; GO:0003007; GO:0005096; GO:0005634; GO:0005737; GO:0005829; GO:0005884; GO:0005901; GO:0005925; GO:0006915; GO:0006919; GO:0007010; GO:0007165; GO:0007202; GO:0008285; GO:0008289; GO:0008360; GO:0017166; GO:0021575; GO:0030036; GO:0030336; GO:0030864; GO:0030900; GO:0032587; GO:0032956; GO:0035023; GO:0035024; GO:0035307; GO:0042169; GO:0043274; GO:0045121; GO:0048041; GO:0051497; GO:0051895; GO:1900119 46905 XM_029350219.2 399 959 307 726 609 Q9R0Z9 5.54e-24 Rho GTPase-activating protein 7 (Deleted in liver cancer 1 protein homolog) (DLC-1) (Rho-type GTPase-activating protein 7) (START domain-containing protein 12) (StARD12) (StAR-related lipid transfer protein 12) Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of phospholipase C activity [GO:0007202]; apoptotic process [GO:0006915]; cytoskeleton organization [GO:0007010]; focal adhesion assembly [GO:0048041]; forebrain development [GO:0030900]; heart morphogenesis [GO:0003007]; hindbrain morphogenesis [GO:0021575]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of stress fiber assembly [GO:0051497]; neural tube closure [GO:0001843]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; regulation of Rho protein signal transduction [GO:0035023]; signal transduction [GO:0007165] GO:0001725; GO:0001843; GO:0003007; GO:0005096; GO:0005634; GO:0005737; GO:0005829; GO:0005884; GO:0005901; GO:0005925; GO:0006915; GO:0006919; GO:0007010; GO:0007165; GO:0007202; GO:0008285; GO:0008289; GO:0008360; GO:0017166; GO:0021575; GO:0030036; GO:0030336; GO:0030864; GO:0030900; GO:0032587; GO:0032956; GO:0035023; GO:0035024; GO:0035307; GO:0042169; GO:0043274; GO:0045121; GO:0048041; GO:0051497; GO:0051895; GO:1900119 46906 XR_006392146.1 47 23 24 13 22 NA NA NA NA NA NA 46907 XM_029338225.2 4065 4829 3445 5509 3841 NA NA NA NA NA NA 46908 XM_029330596.2 29 14 3 7 3 Q8VIG3 1.29e-35 Radial spoke head 1 homolog (Male meiotic metaphase chromosome-associated acidic protein) (Meichroacidin) (Testis-specific gene A2 protein) Mus musculus (Mouse) axoneme assembly [GO:0035082]; meiotic cell cycle [GO:0051321]; spermatid development [GO:0007286] GO:0000794; GO:0001520; GO:0005634; GO:0005737; GO:0005829; GO:0005929; GO:0007286; GO:0031514; GO:0035082; GO:0036126; GO:0051321; GO:0072687 46909 XM_044310788.1 2652 1748 1734 3332 3208 Q7TMY8 0 E3 ubiquitin-protein ligase HUWE1 (EC 2.3.2.26) (E3Histone) (HECT, UBA and WWE domain-containing protein 1) (HECT-type E3 ubiquitin transferase HUWE1) (Upstream regulatory element-binding protein 1) (URE-B1) (URE-binding protein 1) Mus musculus (Mouse) base-excision repair [GO:0006284]; cell differentiation [GO:0030154]; circadian regulation of gene expression [GO:0032922]; Golgi organization [GO:0007030]; histone ubiquitination [GO:0016574]; membrane fusion [GO:0061025]; negative regulation of mitochondrial fusion [GO:0010637]; positive regulation of mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of protein ubiquitination [GO:0031398]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567] GO:0000139; GO:0000209; GO:0003677; GO:0004842; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005829; GO:0006284; GO:0006513; GO:0007030; GO:0010637; GO:0016567; GO:0016574; GO:0030154; GO:0031398; GO:0032922; GO:0043161; GO:0061025; GO:0061630; GO:0098779 46910 XM_044310788.1 2652 1748 1734 3332 3208 Q7TMY8 0 E3 ubiquitin-protein ligase HUWE1 (EC 2.3.2.26) (E3Histone) (HECT, UBA and WWE domain-containing protein 1) (HECT-type E3 ubiquitin transferase HUWE1) (Upstream regulatory element-binding protein 1) (URE-B1) (URE-binding protein 1) Mus musculus (Mouse) base-excision repair [GO:0006284]; cell differentiation [GO:0030154]; circadian regulation of gene expression [GO:0032922]; Golgi organization [GO:0007030]; histone ubiquitination [GO:0016574]; membrane fusion [GO:0061025]; negative regulation of mitochondrial fusion [GO:0010637]; positive regulation of mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of protein ubiquitination [GO:0031398]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567] GO:0000139; GO:0000209; GO:0003677; GO:0004842; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005829; GO:0006284; GO:0006513; GO:0007030; GO:0010637; GO:0016567; GO:0016574; GO:0030154; GO:0031398; GO:0032922; GO:0043161; GO:0061025; GO:0061630; GO:0098779 46911 XM_044310788.1 2652 1748 1734 3332 3208 Q7TMY8 3.62e-139 E3 ubiquitin-protein ligase HUWE1 (EC 2.3.2.26) (E3Histone) (HECT, UBA and WWE domain-containing protein 1) (HECT-type E3 ubiquitin transferase HUWE1) (Upstream regulatory element-binding protein 1) (URE-B1) (URE-binding protein 1) Mus musculus (Mouse) base-excision repair [GO:0006284]; cell differentiation [GO:0030154]; circadian regulation of gene expression [GO:0032922]; Golgi organization [GO:0007030]; histone ubiquitination [GO:0016574]; membrane fusion [GO:0061025]; negative regulation of mitochondrial fusion [GO:0010637]; positive regulation of mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of protein ubiquitination [GO:0031398]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567] GO:0000139; GO:0000209; GO:0003677; GO:0004842; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005829; GO:0006284; GO:0006513; GO:0007030; GO:0010637; GO:0016567; GO:0016574; GO:0030154; GO:0031398; GO:0032922; GO:0043161; GO:0061025; GO:0061630; GO:0098779 46912 XM_044310788.1 2652 1748 1734 3332 3208 Q7TMY8 4.7e-61 E3 ubiquitin-protein ligase HUWE1 (EC 2.3.2.26) (E3Histone) (HECT, UBA and WWE domain-containing protein 1) (HECT-type E3 ubiquitin transferase HUWE1) (Upstream regulatory element-binding protein 1) (URE-B1) (URE-binding protein 1) Mus musculus (Mouse) base-excision repair [GO:0006284]; cell differentiation [GO:0030154]; circadian regulation of gene expression [GO:0032922]; Golgi organization [GO:0007030]; histone ubiquitination [GO:0016574]; membrane fusion [GO:0061025]; negative regulation of mitochondrial fusion [GO:0010637]; positive regulation of mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of protein ubiquitination [GO:0031398]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567] GO:0000139; GO:0000209; GO:0003677; GO:0004842; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005829; GO:0006284; GO:0006513; GO:0007030; GO:0010637; GO:0016567; GO:0016574; GO:0030154; GO:0031398; GO:0032922; GO:0043161; GO:0061025; GO:0061630; GO:0098779 46913 XM_029358424.2 593 576 595 521 811 A5PK45 0 Procollagen galactosyltransferase 1 (EC 2.4.1.50) (Collagen beta(1-O)galactosyltransferase 1) (Glycosyltransferase 25 family member 1) (Hydroxylysine galactosyltransferase 1) Bos taurus (Bovine) positive regulation of collagen fibril organization [GO:1904028] GO:0005788; GO:0050211; GO:1904028 46914 XM_044323886.1 23 0 52 368 0 NA NA NA NA NA NA 46915 XM_044326049.1 1099 589 536 857 1065 A0JNI5 2.12e-47 CLK4-associating serine/arginine rich protein (Splicing factor, arginine/serine-rich 16) Bos taurus (Bovine) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0005634; GO:0006397; GO:0008380 46916 XM_029342600.2 1510 1215 708 3044 2097 Q58A42 2.59e-68 Protein DD3-3 Dictyostelium discoideum (Social amoeba) NA GO:0016020 46917 XM_044307515.1 0 3 2 0 9 NA NA NA NA NA NA 46918 XM_044316692.1 238 54 77 165 183 P23786 2.05e-88 Carnitine O-palmitoyltransferase 2, mitochondrial (EC 2.3.1.21) (Carnitine palmitoyltransferase II) (CPT II) Homo sapiens (Human) carnitine metabolic process [GO:0009437]; carnitine shuttle [GO:0006853]; fatty acid beta-oxidation [GO:0006635]; in utero embryonic development [GO:0001701]; long-chain fatty acid metabolic process [GO:0001676]; positive regulation of cold-induced thermogenesis [GO:0120162] GO:0001676; GO:0001701; GO:0004095; GO:0005654; GO:0005730; GO:0005739; GO:0005743; GO:0006635; GO:0006853; GO:0008458; GO:0009437; GO:0016746; GO:0120162 46919 XM_044317736.1 2283 3645 2038 3092 4872 P23978 0 Sodium- and chloride-dependent GABA transporter 1 (GAT-1) (Solute carrier family 6 member 1) Rattus norvegicus (Rat) associative learning [GO:0008306]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid import [GO:0051939]; inorganic anion import across plasma membrane [GO:0098658]; learning [GO:0007612]; memory [GO:0007613]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; neurotransmitter reuptake [GO:0098810]; positive regulation of gamma-aminobutyric acid secretion [GO:0014054]; response to calcium ion [GO:0051592]; response to cocaine [GO:0042220]; response to estradiol [GO:0032355]; response to inorganic substance [GO:0010035]; response to lead ion [GO:0010288]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to organonitrogen compound [GO:0010243]; response to purine-containing compound [GO:0014074]; response to sucrose [GO:0009744]; response to toxic substance [GO:0009636]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725]; synapse organization [GO:0050808] GO:0005283; GO:0005332; GO:0005886; GO:0007612; GO:0007613; GO:0008306; GO:0009636; GO:0009744; GO:0009986; GO:0010033; GO:0010035; GO:0010243; GO:0010288; GO:0014054; GO:0014070; GO:0014074; GO:0015185; GO:0015378; GO:0030424; GO:0032229; GO:0032355; GO:0035725; GO:0042220; GO:0042734; GO:0042802; GO:0043005; GO:0043025; GO:0045211; GO:0046872; GO:0050808; GO:0051592; GO:0051939; GO:0098658; GO:0098719; GO:0098793; GO:0098810; GO:0098982; GO:1902476 46920 XR_006395415.1 185 264 128 244 214 B2RQR8 1.35e-129 Endothelin-converting enzyme 2 (ECE-2) (EC 3.4.24.71) Mus musculus (Mouse) peptide hormone processing [GO:0016486]; protein processing [GO:0016485] GO:0000139; GO:0004222; GO:0005802; GO:0005886; GO:0016485; GO:0016486; GO:0030658; GO:0030659; GO:0046872 46921 XM_044325683.1 41 63 13 55 67 E9Q236 0 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 46922 XM_044311252.1 47 2 18 23 26 NA NA NA NA NA NA 46923 XR_006391941.1 20 9 22 21 39 NA NA NA NA NA NA 46924 XM_044308941.1 0 0 7 8 3 NA NA NA NA NA NA 46925 XM_044321388.1 0 0 6 37 23 NA NA NA NA NA NA 46926 XM_029344498.2 0 10 0 12 3 NA NA NA NA NA NA 46927 XM_044328209.1 21 0 9 22 24 NA NA NA NA NA NA 46928 XM_029339815.2 15 14 0 21 50 Q9IAK8 1.52e-45 T-box transcription factor TBX5-A (zftbx5a) (T-box protein 5) (zTbx5) Danio rerio (Zebrafish) (Brachydanio rerio) animal organ morphogenesis [GO:0009887]; atrial ventricular junction remodeling [GO:0003294]; atrioventricular canal development [GO:0036302]; atrioventricular valve formation [GO:0003190]; cardiac left ventricle formation [GO:0003218]; cardiac muscle cell differentiation [GO:0055007]; cardiac muscle tissue regeneration [GO:0061026]; cell fate specification [GO:0001708]; DNA-templated transcription [GO:0006351]; embryonic heart tube development [GO:0035050]; embryonic heart tube morphogenesis [GO:0003143]; embryonic pectoral fin morphogenesis [GO:0035118]; heart development [GO:0007507]; heart jogging [GO:0003146]; heart looping [GO:0001947]; heart morphogenesis [GO:0003007]; limb bud formation [GO:0060174]; optic nerve development [GO:0021554]; pattern specification process [GO:0007389]; pectoral fin development [GO:0033339]; pectoral fin morphogenesis [GO:0035138]; pericardium morphogenesis [GO:0003344]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proepicardium development [GO:0003342]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; retina morphogenesis in camera-type eye [GO:0060042] GO:0000978; GO:0000981; GO:0001708; GO:0001947; GO:0003007; GO:0003143; GO:0003146; GO:0003190; GO:0003218; GO:0003294; GO:0003342; GO:0003344; GO:0003700; GO:0005634; GO:0005737; GO:0006351; GO:0006355; GO:0006357; GO:0007389; GO:0007507; GO:0009887; GO:0015629; GO:0021554; GO:0032991; GO:0032993; GO:0033339; GO:0035050; GO:0035118; GO:0035138; GO:0036302; GO:0043565; GO:0045893; GO:0045944; GO:0055007; GO:0060042; GO:0060174; GO:0061026 46929 XM_044312935.1 34 19 26 16 55 P59046 1.67e-44 NACHT, LRR and PYD domains-containing protein 12 (Monarch-1) (PYRIN-containing APAF1-like protein 7) (Regulated by nitric oxide) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cellular response to cytokine stimulus [GO:0071345]; dendritic cell migration [GO:0036336]; ERK1 and ERK2 cascade [GO:0070371]; negative regulation of cytokine production [GO:0001818]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of signal transduction [GO:0009968]; negative regulation of Toll signaling pathway [GO:0045751]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of inflammatory response [GO:0050727]; regulation of interleukin-18 production [GO:0032661]; signal transduction [GO:0007165] GO:0001818; GO:0005524; GO:0005737; GO:0005829; GO:0006919; GO:0007165; GO:0008656; GO:0009968; GO:0031953; GO:0032088; GO:0032661; GO:0032692; GO:0032715; GO:0032731; GO:0036336; GO:0038061; GO:0043122; GO:0043124; GO:0043281; GO:0045345; GO:0045751; GO:0050727; GO:0050728; GO:0050729; GO:0070371; GO:0070373; GO:0071345; GO:1901223; GO:1901224 46930 XR_006391431.1 124 82 27 268 252 NA NA NA NA NA NA 46931 XM_044324775.1 0 0 102 65 0 NA NA NA NA NA NA 46932 XM_029327491.2 57 42 97 65 331 NA NA NA NA NA NA 46933 XM_044328753.1 6 25 12 12 30 Q7TN88 1.1e-60 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 46934 XM_044328753.1 6 25 12 12 30 Q7TN88 1.34e-50 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 46935 XR_006393824.1 297 57 149 65 603 NA NA NA NA NA NA 46936 XM_029338477.2 400 0 0 0 26 NA NA NA NA NA NA 46937 XM_044327518.1 62 103 32 27 176 NA NA NA NA NA NA 46938 XM_044306825.1 55 40 16 44 31 A0A2B4RP11 3.55e-21 NA NA NA NA 46939 XM_044319033.1 4047 3642 3405 2570 3182 Q01460 1.19e-102 Di-N-acetylchitobiase (EC 3.2.1.-) Rattus norvegicus (Rat) chitin catabolic process [GO:0006032]; oligosaccharide catabolic process [GO:0009313] GO:0004568; GO:0005764; GO:0006032; GO:0008061; GO:0009313; GO:0016798 46940 XM_029336851.2 193 88 118 168 82 NA NA NA NA NA NA 46941 XM_044320833.1 349 58 246 216 609 Q8BHB0 1.19e-29 Nucleotide-binding oligomerization domain-containing protein 1 (Caspase recruitment domain-containing protein 4) Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cellular response to muramyl dipeptide [GO:0071225]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; ERK1 and ERK2 cascade [GO:0070371]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of cell death [GO:0010942]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of xenophagy [GO:1904417]; regulation of apoptotic process [GO:0042981]; stress-activated MAPK cascade [GO:0051403]; xenophagy [GO:0098792] GO:0002221; GO:0002606; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006915; GO:0006919; GO:0007249; GO:0007254; GO:0010942; GO:0016045; GO:0016323; GO:0016324; GO:0032731; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0035556; GO:0038187; GO:0042742; GO:0042802; GO:0042803; GO:0042981; GO:0043123; GO:0043280; GO:0044877; GO:0045087; GO:0045335; GO:0046330; GO:0050700; GO:0050830; GO:0051000; GO:0051092; GO:0051403; GO:0060907; GO:0070371; GO:0070374; GO:0071225; GO:0098792; GO:1901224; GO:1904417 46942 XM_029334616.2 253 71 0 361 0 W8W138 6.2e-48 Beta-secretase (EC 3.4.23.-) Strongylocentrotus purpuratus (Purple sea urchin) amyloid-beta metabolic process [GO:0050435]; membrane protein ectodomain proteolysis [GO:0006509]; proteolysis [GO:0006508] GO:0004190; GO:0005768; GO:0005802; GO:0005886; GO:0006508; GO:0006509; GO:0050435 46943 XM_044324009.1 0 29 5 51 9 NA NA NA NA NA NA 46944 XM_044322437.1 0 0 79 0 0 Q01133 8.58e-31 Antho-RFamide neuropeptides [Cleaved into: Antho-RFamide] Calliactis parasitica (Sea anemone) (Actinia parasitica) neuropeptide signaling pathway [GO:0007218] GO:0005576; GO:0007218 46945 XM_044322437.1 0 0 79 0 0 Q01133 3.31e-28 Antho-RFamide neuropeptides [Cleaved into: Antho-RFamide] Calliactis parasitica (Sea anemone) (Actinia parasitica) neuropeptide signaling pathway [GO:0007218] GO:0005576; GO:0007218 46946 XM_044322241.1 424 207 243 366 465 NA NA NA NA NA NA 46947 XM_029357007.2 56 0 23 2 36 NA NA NA NA NA NA 46948 XM_044319020.1 1994 1798 1149 1879 1577 Q9VL13 8.43e-101 MOB kinase activator-like 3 (Mob as tumor suppressor protein 3) (Dmob3) (Mps one binder kinase activator-like 3) Drosophila melanogaster (Fruit fly) positive regulation of protein phosphorylation [GO:0001934]; signal transduction [GO:0007165] GO:0001934; GO:0005634; GO:0005737; GO:0007165; GO:0019901; GO:0030295; GO:0046872 46949 XR_006395923.1 275 451 252 299 215 Q9BWV7 9.5e-107 Probable tubulin polyglutamylase TTLL2 (EC 6.-.-.-) (Testis-specific protein NYD-TSPG) (Tubulin--tyrosine ligase-like protein 2) Homo sapiens (Human) microtubule cytoskeleton organization [GO:0000226]; protein polyglutamylation [GO:0018095] GO:0000226; GO:0005524; GO:0005929; GO:0015631; GO:0018095; GO:0046872; GO:0070740 46950 XM_029332902.2 471 106 278 386 822 NA NA NA NA NA NA 46951 XM_029356814.2 143 29 7 48 134 NA NA NA NA NA NA 46952 XM_044309655.1 19 5 8 6 12 NA NA NA NA NA NA 46953 XR_006394761.1 42 23 23 50 68 NA NA NA NA NA NA 46954 XM_044317819.1 0 396 357 928 600 Q7KTX8 8.96e-66 Mediator of RNA polymerase II transcription subunit 13 (Mediator complex subunit 13) (Mediator complex subunit Skuld) (Protein blind spot) (Protein poils aux pattes) (dTRAP240) Drosophila melanogaster (Fruit fly) cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; compound eye development [GO:0048749]; imaginal disc-derived leg segmentation [GO:0036011]; larval somatic muscle development [GO:0007526]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; regulation of transcription by RNA polymerase II [GO:0006357]; sex comb development [GO:0045498]; transcription initiation at RNA polymerase II promoter [GO:0006367]; wing disc dorsal/ventral pattern formation [GO:0048190] GO:0003712; GO:0005634; GO:0005654; GO:0006357; GO:0006367; GO:0007526; GO:0016592; GO:0022416; GO:0036011; GO:0045165; GO:0045498; GO:0048190; GO:0048749; GO:0070847; GO:0090263 46955 XM_044317819.1 0 396 357 928 600 Q7KTX8 6.28e-46 Mediator of RNA polymerase II transcription subunit 13 (Mediator complex subunit 13) (Mediator complex subunit Skuld) (Protein blind spot) (Protein poils aux pattes) (dTRAP240) Drosophila melanogaster (Fruit fly) cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; compound eye development [GO:0048749]; imaginal disc-derived leg segmentation [GO:0036011]; larval somatic muscle development [GO:0007526]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; regulation of transcription by RNA polymerase II [GO:0006357]; sex comb development [GO:0045498]; transcription initiation at RNA polymerase II promoter [GO:0006367]; wing disc dorsal/ventral pattern formation [GO:0048190] GO:0003712; GO:0005634; GO:0005654; GO:0006357; GO:0006367; GO:0007526; GO:0016592; GO:0022416; GO:0036011; GO:0045165; GO:0045498; GO:0048190; GO:0048749; GO:0070847; GO:0090263 46956 XM_044307000.1 0 0 6 25 0 NA NA NA NA NA NA 46957 XM_029332306.2 27 48 25 24 44 NA NA NA NA NA NA 46958 XM_029358076.2 478 404 240 89 343 NA NA NA NA NA NA 46959 XM_044312649.1 0 0 0 8 0 NA NA NA NA NA NA 46960 XM_029342402.2 162 37 157 206 118 Q9LQV2 4.19e-50 RNA-dependent RNA polymerase 1 (AtRDRP1) (EC 2.7.7.48) (RNA-directed RNA polymerase 1) Arabidopsis thaliana (Mouse-ear cress) defense response [GO:0006952]; positive regulation of post-transcriptional gene silencing [GO:0060148]; response to salicylic acid [GO:0009751]; response to virus [GO:0009615]; siRNA processing [GO:0030422]; wax biosynthetic process [GO:0010025] GO:0003723; GO:0003968; GO:0006952; GO:0009615; GO:0009751; GO:0010025; GO:0030422; GO:0031380; GO:0060148 46961 XM_044327995.1 8 0 0 0 0 NA NA NA NA NA NA 46962 XM_044326787.1 1480 1095 954 1600 1550 Q64487 1.49e-125 Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48) Mus musculus (Mouse) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; neuron differentiation [GO:0030182]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse assembly [GO:0051965]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; regulation of immune response [GO:0050776]; regulation of postsynaptic density assembly [GO:0099151]; synaptic membrane adhesion [GO:0099560]; trans-synaptic signaling [GO:0099537]; trans-synaptic signaling by trans-synaptic complex [GO:0099545] GO:0004725; GO:0005102; GO:0006470; GO:0007157; GO:0030182; GO:0042734; GO:0046426; GO:0050775; GO:0050776; GO:0050804; GO:0050839; GO:0051965; GO:0097105; GO:0098685; GO:0098686; GO:0098978; GO:0099054; GO:0099151; GO:0099537; GO:0099545; GO:0099560 46963 XM_044326787.1 1480 1095 954 1600 1550 Q64487 3.36e-45 Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48) Mus musculus (Mouse) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; neuron differentiation [GO:0030182]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse assembly [GO:0051965]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; regulation of immune response [GO:0050776]; regulation of postsynaptic density assembly [GO:0099151]; synaptic membrane adhesion [GO:0099560]; trans-synaptic signaling [GO:0099537]; trans-synaptic signaling by trans-synaptic complex [GO:0099545] GO:0004725; GO:0005102; GO:0006470; GO:0007157; GO:0030182; GO:0042734; GO:0046426; GO:0050775; GO:0050776; GO:0050804; GO:0050839; GO:0051965; GO:0097105; GO:0098685; GO:0098686; GO:0098978; GO:0099054; GO:0099151; GO:0099537; GO:0099545; GO:0099560 46964 XM_029327423.2 46 25 148 181 82 P63138 2.87e-58 Gamma-aminobutyric acid receptor subunit beta-2 (GABA(A) receptor subunit beta-2) Rattus norvegicus (Rat) cellular response to histamine [GO:0071420]; chemical synaptic transmission [GO:0007268]; chemical synaptic transmission, postsynaptic [GO:0099565]; chloride transmembrane transport [GO:1902476]; cochlea development [GO:0090102]; gamma-aminobutyric acid signaling pathway [GO:0007214]; inhibitory synapse assembly [GO:1904862]; inner ear receptor cell development [GO:0060119]; innervation [GO:0060384]; ion transmembrane transport [GO:0034220]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; nervous system process [GO:0050877]; neuron development [GO:0048666]; regulation of membrane potential [GO:0042391]; regulation of neuron apoptotic process [GO:0043523]; regulation of postsynaptic membrane potential [GO:0060078]; sensory perception of sound [GO:0007605]; signal transduction [GO:0007165]; synaptic transmission, GABAergic [GO:0051932] GO:0004890; GO:0005231; GO:0005237; GO:0005254; GO:0005829; GO:0005886; GO:0007165; GO:0007214; GO:0007268; GO:0007605; GO:0016020; GO:0022851; GO:0030594; GO:0030659; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0043523; GO:0043524; GO:0045202; GO:0048666; GO:0048787; GO:0050877; GO:0051932; GO:0060078; GO:0060119; GO:0060384; GO:0071420; GO:0090102; GO:0098978; GO:0098982; GO:0099507; GO:0099565; GO:0099634; GO:1901215; GO:1902476; GO:1902710; GO:1902711; GO:1904315; GO:1904862 46965 XM_044320423.1 103 157 183 92 83 NA NA NA NA NA NA 46966 XM_029356550.2 1 0 1 0 8 NA NA NA NA NA NA 46967 XM_029351890.2 41 18 21 12 40 NA NA NA NA NA NA 46968 XM_029354063.2 29 4 41 19 220 NA NA NA NA NA NA 46969 XM_029333488.2 20037 13941 16281 33080 17597 NA NA NA NA NA NA 46970 XR_006395401.1 853 1007 253 1211 679 NA NA NA NA NA NA 46971 XM_029343559.2 876 424 395 481 557 NA NA NA NA NA NA 46972 XM_044320321.1 1177 663 525 848 397 Q32LE3 1.38e-95 Centrin-1 Bos taurus (Bovine) cell division [GO:0051301]; centriole replication [GO:0007099]; mitotic cell cycle [GO:0000278]; nucleotide-excision repair [GO:0006289] GO:0000278; GO:0000922; GO:0005509; GO:0005737; GO:0005813; GO:0005814; GO:0006289; GO:0007099; GO:0051301 46973 XM_029358128.2 101 14 13 53 20 A3BF39 7.9e-122 Cadmium/zinc-transporting ATPase HMA2 (EC 7.2.2.12) (EC 7.2.2.21) (Protein HEAVY METAL ATPASE 2) (OsHMA2) Oryza sativa subsp. japonica (Rice) NA GO:0005385; GO:0005524; GO:0005886; GO:0008551; GO:0015086; GO:0016463; GO:0016887; GO:0046872 46974 XM_044318809.1 81 178 0 225 0 B3EWY9 0 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 46975 XM_044318809.1 81 178 0 225 0 B3EWY9 0 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 46976 XM_044318809.1 81 178 0 225 0 B3EWY9 3.93e-33 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 46977 XM_029336820.2 22 58 0 0 63 Q5VVW2 0 GTPase-activating Rap/Ran-GAP domain-like protein 3 Homo sapiens (Human) activation of GTPase activity [GO:0090630]; regulation of small GTPase mediated signal transduction [GO:0051056] GO:0005096; GO:0005737; GO:0051056; GO:0090630 46978 XM_044313012.1 62 2 11 15 27 NA NA NA NA NA NA 46979 XM_029358535.2 324 246 205 314 447 Q7SXL7 3.04e-106 Pre-mRNA-splicing regulator WTAP (Female-lethal(2)D homolog) (WT1-associated protein) (Wilms tumor 1-associating protein) Danio rerio (Zebrafish) (Brachydanio rerio) cell cycle [GO:0007049]; mRNA methylation [GO:0080009]; mRNA processing [GO:0006397]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of apoptotic process [GO:0042981]; RNA splicing [GO:0008380] GO:0000381; GO:0005634; GO:0005737; GO:0006397; GO:0007049; GO:0008380; GO:0016607; GO:0036396; GO:0042981; GO:0080009 46980 XM_029351554.2 29 18 12 55 22 NA NA NA NA NA NA 46981 XM_029338081.2 325 113 130 336 181 Q5RFD0 6.2e-38 2',3'-cyclic-nucleotide 3'-phosphodiesterase (CNP) (CNPase) (EC 3.1.4.37) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cyclic nucleotide catabolic process [GO:0009214] GO:0003723; GO:0004113; GO:0009214; GO:0016020; GO:0042470 46982 XR_006394441.1 19 48 1 8 38 NA NA NA NA NA NA 46983 XM_044307152.1 0 128 0 0 69 Q9UHC1 1.53e-88 DNA mismatch repair protein Mlh3 (MutL protein homolog 3) Homo sapiens (Human) female meiosis I [GO:0007144]; male meiotic nuclear division [GO:0007140]; mismatch repair [GO:0006298]; protein localization [GO:0008104]; reciprocal meiotic recombination [GO:0007131]; synaptonemal complex assembly [GO:0007130] GO:0000795; GO:0001673; GO:0003682; GO:0003696; GO:0005524; GO:0005634; GO:0005654; GO:0005712; GO:0006298; GO:0007130; GO:0007131; GO:0007140; GO:0007144; GO:0008104; GO:0016887; GO:0019237; GO:0030983; GO:0032300; GO:0140664 46984 XM_044307152.1 0 128 0 0 69 Q9UHC1 1.3e-56 DNA mismatch repair protein Mlh3 (MutL protein homolog 3) Homo sapiens (Human) female meiosis I [GO:0007144]; male meiotic nuclear division [GO:0007140]; mismatch repair [GO:0006298]; protein localization [GO:0008104]; reciprocal meiotic recombination [GO:0007131]; synaptonemal complex assembly [GO:0007130] GO:0000795; GO:0001673; GO:0003682; GO:0003696; GO:0005524; GO:0005634; GO:0005654; GO:0005712; GO:0006298; GO:0007130; GO:0007131; GO:0007140; GO:0007144; GO:0008104; GO:0016887; GO:0019237; GO:0030983; GO:0032300; GO:0140664 46985 XM_029344989.2 989 1032 578 1283 1189 P10860 0 Glutamate dehydrogenase 1, mitochondrial (GDH 1) (EC 1.4.1.3) (Memory-related gene 2 protein) (MRG-2) Rattus norvegicus (Rat) cerebellum development [GO:0021549]; glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; long-term memory [GO:0007616]; positive regulation of insulin secretion [GO:0032024]; response to aluminum ion [GO:0010044]; tricarboxylic acid metabolic process [GO:0072350] GO:0004352; GO:0004353; GO:0004354; GO:0005524; GO:0005525; GO:0005737; GO:0005739; GO:0005759; GO:0005783; GO:0006537; GO:0006538; GO:0006541; GO:0007616; GO:0010044; GO:0019899; GO:0021549; GO:0032024; GO:0043531; GO:0070403; GO:0070728; GO:0072350 46986 XM_044326464.1 135 49 78 41 41 Q6P7Q4 2.18e-60 Lactoylglutathione lyase (EC 4.4.1.5) (Aldoketomutase) (Glyoxalase I) (Glx I) (Ketone-aldehyde mutase) (Methylglyoxalase) (S-D-lactoylglutathione methylglyoxal lyase) Rattus norvegicus (Rat) carbohydrate metabolic process [GO:0005975]; glutathione metabolic process [GO:0006749]; methylglyoxal metabolic process [GO:0009438]; negative regulation of apoptotic process [GO:0043066]; osteoclast differentiation [GO:0030316]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0004462; GO:0005654; GO:0005829; GO:0005886; GO:0005975; GO:0006357; GO:0006749; GO:0008270; GO:0009438; GO:0030316; GO:0043066 46987 XR_003826742.2 0 9 11 33 16 NA NA NA NA NA NA 46988 XM_029350576.2 247 111 94 233 396 Q1ZZH1 2.03e-169 Metabotropic glutamate receptor 3 (mGluR3) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0004930; GO:0005886; GO:0008066 46989 XM_044315019.1 3 10 6 0 3 NA NA NA NA NA NA 46990 XM_029330980.2 5175 4844 3037 4263 4622 Q8ISN9 1.85e-36 40S ribosomal protein S25 Branchiostoma belcheri (Amphioxus) NA GO:0005840; GO:1990904 46991 XR_006397969.1 22 40 72 24 70 NA NA NA NA NA NA 46992 XM_029336067.2 141 50 54 168 146 Q8R1C6 1.59e-64 Methyltransferase-like protein 22 (EC 2.1.1.-) Mus musculus (Mouse) protein methylation [GO:0006479] GO:0005634; GO:0005654; GO:0005730; GO:0006479; GO:0008276; GO:0018024; GO:0031072; GO:0032991 46993 XM_044324858.1 2672 1879 1181 3501 2426 A4QNP7 3.47e-36 Doublesex- and mab-3-related transcription factor A2 (Doublesex- and mab-3-related transcription factor 5) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006355; GO:0043565; GO:0046872 46994 XM_044319292.1 86 0 4 0 0 Q8R4K8 0 Pappalysin-1 (EC 3.4.24.79) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase) (Pregnancy-associated plasma protein A) (PAPP-A) Mus musculus (Mouse) cell surface receptor signaling pathway [GO:0007166]; female pregnancy [GO:0007565]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to dexamethasone [GO:0071548]; response to follicle-stimulating hormone [GO:0032354] GO:0004175; GO:0004222; GO:0005576; GO:0005615; GO:0006508; GO:0007166; GO:0007565; GO:0008237; GO:0030163; GO:0032354; GO:0046872; GO:0071548 46995 XM_044308217.1 305 186 187 148 195 Q5VVX9 1.1e-41 Ubiquitin-conjugating enzyme E2 U (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme U) (Ubiquitin carrier protein U) (Ubiquitin-protein ligase U) Homo sapiens (Human) DNA repair [GO:0006281]; histone ubiquitination [GO:0016574]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209] GO:0000209; GO:0005524; GO:0006281; GO:0016574; GO:0033503; GO:0043161; GO:0061631 46996 XM_029358592.2 1052 2064 1034 1021 1009 Q9FE17 1.64e-61 NAD-dependent protein deacetylase SRT1 (EC 2.3.1.286) (Regulatory protein SIR2 homolog 1) (SIR2-like protein 1) Arabidopsis thaliana (Mouse-ear cress) ethylene-activated signaling pathway [GO:0009873]; histone H3 deacetylation [GO:0070932]; histone H3-K9 acetylation [GO:0043970]; negative regulation of transcription by RNA polymerase II [GO:0000122] GO:0000122; GO:0003714; GO:0004407; GO:0005634; GO:0009873; GO:0016740; GO:0019213; GO:0031490; GO:0043970; GO:0046872; GO:0070403; GO:0070932 46997 XM_044316920.1 16 67 51 90 106 NA NA NA NA NA NA 46998 XM_044326476.1 98 29 0 24 0 Q9Y5R4 2.64e-68 MTRF1L release factor glutamine methyltransferase (EC 2.1.1.297) (HemK methyltransferase family member 1) (M.HsaHemKP) Homo sapiens (Human) DNA methylation [GO:0006306] GO:0003677; GO:0005739; GO:0006306; GO:0008170; GO:0008276; GO:0008757; GO:0102559 46999 XM_044316527.1 1985 1735 1376 2408 1723 A3BF39 2.49e-105 Cadmium/zinc-transporting ATPase HMA2 (EC 7.2.2.12) (EC 7.2.2.21) (Protein HEAVY METAL ATPASE 2) (OsHMA2) Oryza sativa subsp. japonica (Rice) NA GO:0005385; GO:0005524; GO:0005886; GO:0008551; GO:0015086; GO:0016463; GO:0016887; GO:0046872 47000 XM_044313778.1 0 0 0 0 10 NA NA NA NA NA NA 47001 XR_006397007.1 7 18 20 56 55 NA NA NA NA NA NA 47002 XM_029356780.2 151 140 85 142 132 Q5JXC2 2.48e-30 Migration and invasion-inhibitory protein (IGFBP2-binding protein) (Invasion-inhibitory protein 45) (IIp45) Homo sapiens (Human) negative regulation of cell migration [GO:0030336]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972] GO:0010972; GO:0030336 47003 XR_006395436.1 0 0 0 0 281 NA NA NA NA NA NA 47004 XM_044321439.1 60 33 183 32 537 Q7T163 0 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 47005 XM_044321439.1 60 33 183 32 537 Q7T163 3.74e-42 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 47006 XM_044321439.1 60 33 183 32 537 Q7T163 3.69e-33 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 47007 XM_044321439.1 60 33 183 32 537 Q7T163 2.36e-29 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 47008 XM_044321439.1 60 33 183 32 537 Q7T163 5.97e-27 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 47009 XM_044321439.1 60 33 183 32 537 Q7T163 1.39e-22 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 47010 XM_044318486.1 1148 449 182 820 915 P00532 1.13e-28 Serine/threonine-protein kinase-transforming protein raf (EC 2.7.11.1) Murine sarcoma virus 3611 protein phosphorylation [GO:0006468] GO:0004674; GO:0005524; GO:0006468; GO:0106310 47011 XM_044307974.1 770 2046 562 8 367 Q29599 1.68e-39 2'-5'-oligoadenylate synthase 1 ((2-5')oligo(A) synthase 1) (2-5A synthase 1) (EC 2.7.7.84) (p42 OAS) Sus scrofa (Pig) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; regulation of ribonuclease activity [GO:0060700] GO:0001730; GO:0003725; GO:0005524; GO:0005576; GO:0005654; GO:0005737; GO:0005739; GO:0005783; GO:0005829; GO:0016020; GO:0045071; GO:0045087; GO:0046872; GO:0051607; GO:0060700 47012 XM_029332959.2 25310 36636 18687 23484 19325 Q2YGT9 8.43e-43 60S ribosomal protein L6 Sus scrofa (Pig) cytoplasmic translation [GO:0002181]; ribosomal large subunit assembly [GO:0000027] GO:0000027; GO:0002181; GO:0003723; GO:0003735; GO:0005634; GO:0014069; GO:0015934; GO:0022625; GO:0036464; GO:0042788; GO:0098556 47013 XM_044323063.1 94 0 75 57 95 NA NA NA NA NA NA 47014 XM_044308294.1 0 0 0 62 0 NA NA NA NA NA NA 47015 XM_029339824.2 0 9 0 8 24 NA NA NA NA NA NA 47016 XM_029344427.2 1057 96 120 90 3 Q8IWW6 1.09e-82 Rho GTPase-activating protein 12 (Rho-type GTPase-activating protein 12) Homo sapiens (Human) actin filament organization [GO:0007015]; morphogenesis of an epithelial sheet [GO:0002011]; negative regulation of small GTPase mediated signal transduction [GO:0051058]; phagocytosis, engulfment [GO:0006911]; regulation of GTPase activity [GO:0043087]; signal transduction [GO:0007165] GO:0001891; GO:0002011; GO:0005096; GO:0005737; GO:0006911; GO:0007015; GO:0007165; GO:0043087; GO:0051058 47017 XM_029327185.2 0 8 0 0 0 Q96DM1 3.51e-55 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 47018 XM_029327185.2 0 8 0 0 0 Q96DM1 3.51e-55 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 47019 XM_044320213.1 27 21 0 143 108 NA NA NA NA NA NA 47020 XM_029349174.2 11121 10306 9690 26014 15428 NA NA NA NA NA NA 47021 XM_044310007.1 303 64 82 197 125 P16157 9.36e-76 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 47022 XM_044310007.1 303 64 82 197 125 P16157 1.15e-66 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 47023 XM_044310007.1 303 64 82 197 125 P16157 6.88e-62 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 47024 XM_044310007.1 303 64 82 197 125 P16157 3.53e-57 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 47025 XM_044310007.1 303 64 82 197 125 P16157 1.96e-51 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 47026 XM_044308824.1 38 11 17 69 14 NA NA NA NA NA NA 47027 XM_029348578.2 0 8 0 26 0 P59722 2.88e-69 Egl nine homolog 1 (EC 1.14.11.29) (Hypoxia-inducible factor prolyl hydroxylase 2) (HIF-PH2) (HIF-prolyl hydroxylase 2) (HPH-2) (Prolyl hydroxylase domain-containing protein 2) (PHD2) Rattus norvegicus (Rat) cardiac muscle tissue morphogenesis [GO:0055008]; cellular iron ion homeostasis [GO:0006879]; cellular oxygen homeostasis [GO:0032364]; cellular response to hypoxia [GO:0071456]; heart trabecula formation [GO:0060347]; labyrinthine layer development [GO:0060711]; negative regulation of CAMKK-AMPK signaling cascade [GO:1905290]; negative regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051344]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; positive regulation of apoptotic process [GO:0043065]; positive regulation of neuron death [GO:1901216]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of angiogenesis [GO:0045765]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of neuron death [GO:1901214]; regulation of postsynapse organization [GO:0099175]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation protein catabolic process at postsynapse [GO:0140252]; response to hypoxia [GO:0001666]; response to nitric oxide [GO:0071731]; ventricular septum morphogenesis [GO:0060412] GO:0001666; GO:0005634; GO:0005737; GO:0005829; GO:0006879; GO:0008198; GO:0014069; GO:0016706; GO:0018401; GO:0019899; GO:0031418; GO:0031543; GO:0031545; GO:0032364; GO:0043065; GO:0043433; GO:0045765; GO:0045944; GO:0051344; GO:0055008; GO:0060347; GO:0060412; GO:0060711; GO:0071456; GO:0071731; GO:0098978; GO:0099159; GO:0099175; GO:0099576; GO:0140252; GO:1901214; GO:1901216; GO:1905290 47028 XR_006397520.1 63 98 70 1 0 NA NA NA NA NA NA 47029 XM_029332681.2 779 725 493 420 757 Q9VY86 7.31e-59 TM2 domain-containing protein CG11103 Drosophila melanogaster (Fruit fly) positive regulation of Notch signaling pathway [GO:0045747] GO:0005886; GO:0045747 47030 XM_044318590.1 70 206 45 245 113 Q9D6Y9 0 1,4-alpha-glucan-branching enzyme (EC 2.4.1.18) (Brancher enzyme) (Glycogen-branching enzyme) Mus musculus (Mouse) carbohydrate metabolic process [GO:0005975]; glycogen biosynthetic process [GO:0005978]; negative regulation of neuron apoptotic process [GO:0043524] GO:0003844; GO:0004553; GO:0005737; GO:0005829; GO:0005975; GO:0005978; GO:0030246; GO:0043169; GO:0043524; GO:0102752 47031 XM_044312403.1 88 44 135 129 234 NA NA NA NA NA NA 47032 XM_044328414.1 48 48 40 46 70 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 47033 XM_044328414.1 48 48 40 46 70 Q96AY4 5.9e-159 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 47034 XM_044328414.1 48 48 40 46 70 Q96AY4 5e-153 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 47035 XM_044328414.1 48 48 40 46 70 Q96AY4 5.17e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 47036 XM_044324452.1 26 45 64 64 0 NA NA NA NA NA NA 47037 XM_029324361.2 113 40 90 106 170 NA NA NA NA NA NA 47038 XR_006396572.1 1172 1111 739 1351 1327 NA NA NA NA NA NA 47039 XR_006395120.1 5 56 0 278 279 NA NA NA NA NA NA 47040 XM_029334539.2 0 0 5 0 15 NA NA NA NA NA NA 47041 XM_029346507.2 255 204 106 119 17 NA NA NA NA NA NA 47042 XM_044315996.1 0 28 0 6 0 NA NA NA NA NA NA 47043 XM_029336627.2 514 585 315 476 424 Q9Y2B0 1.4e-36 Protein canopy homolog 2 (MIR-interacting saposin-like protein) (Putative secreted protein Zsig9) (Transmembrane protein 4) Homo sapiens (Human) negative regulation of gene expression [GO:0010629]; positive regulation of low-density lipoprotein receptor activity [GO:1905599]; regulation of low-density lipoprotein particle clearance [GO:0010988] GO:0005783; GO:0010629; GO:0010988; GO:1905599 47044 XM_029345449.2 29 11 0 30 0 NA NA NA NA NA NA 47045 XM_029342185.2 18 10 21 273 113 Q9UKP5 8.04e-114 A disintegrin and metalloproteinase with thrombospondin motifs 6 (ADAM-TS 6) (ADAM-TS6) (ADAMTS-6) (EC 3.4.24.-) Homo sapiens (Human) aorta development [GO:0035904]; cardiac septum development [GO:0003279]; coronary vasculature development [GO:0060976]; extracellular matrix organization [GO:0030198]; kidney development [GO:0001822]; proteolysis [GO:0006508] GO:0001822; GO:0003279; GO:0004222; GO:0005576; GO:0006508; GO:0008237; GO:0030198; GO:0031012; GO:0035904; GO:0046872; GO:0060976 47046 XM_044319269.1 0 10 0 15 0 NA NA NA NA NA NA 47047 XM_044312696.1 0 27 0 0 43 NA NA NA NA NA NA 47048 XM_029330423.2 4 0 0 0 25 Q9EQD2 8.21e-38 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 47049 XR_006395815.1 47 85 24 44 50 NA NA NA NA NA NA 47050 XR_006397945.1 21 34 30 22 11 NA NA NA NA NA NA 47051 XM_044319328.1 2 0 11 0 0 NA NA NA NA NA NA 47052 XR_006394938.1 81 80 18 48 31 NA NA NA NA NA NA 47053 XM_044322416.1 2328 1583 891 1298 1341 O19072 3.04e-148 Ornithine transcarbamylase, mitochondrial (OTCase) (EC 2.1.3.3) (Ornithine carbamoyltransferase, mitochondrial) Sus scrofa (Pig) arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]; urea cycle [GO:0000050] GO:0000050; GO:0004585; GO:0005739; GO:0005743; GO:0005759; GO:0016597; GO:0019240; GO:0042450; GO:0043231 47054 XM_044321385.1 151 141 86 79 125 A0JMW2 0 Dynein axonemal assembly factor 5 (HEAT repeat-containing protein 2) Xenopus laevis (African clawed frog) cell projection organization [GO:0030030] GO:0030030; GO:0120293 47055 XM_029358470.2 38 0 35 2 209 NA NA NA NA NA NA 47056 XM_029347896.2 62 174 86 127 115 Q9H6E4 2.32e-39 Coiled-coil domain-containing protein 134 Homo sapiens (Human) angiogenesis [GO:0001525]; embryonic hemopoiesis [GO:0035162]; embryonic liver development [GO:1990402]; placenta development [GO:0001890]; regulation of ossification [GO:0030278]; ventricular system development [GO:0021591] GO:0001525; GO:0001890; GO:0005576; GO:0005634; GO:0005783; GO:0016020; GO:0021591; GO:0030278; GO:0035162; GO:1990402 47057 XM_044307738.1 24 44 0 0 0 NA NA NA NA NA NA 47058 XR_006393579.1 85 154 9 68 46 NA NA NA NA NA NA 47059 XM_044309650.1 574 450 214 541 191 A0A3M6TIF0 0 NA NA NA NA 47060 XM_044316783.1 1458 1907 1018 2104 1732 A0JPG1 0 FHF complex subunit HOOK interacting protein 2A (FHIP2A) Xenopus laevis (African clawed frog) NA NA 47061 XR_006396841.1 0 122 14 88 70 NA NA NA NA NA NA 47062 XR_006392521.1 105 39 86 73 74 NA NA NA NA NA NA 47063 XM_044307415.1 59 0 35 11 25 NA NA NA NA NA NA 47064 XM_044313299.1 0 3 4 0 38 NA NA NA NA NA NA 47065 XM_044318855.1 643 480 386 678 520 P46871 0 Kinesin-II 95 kDa subunit (KRP-85/95 95 kDa subunit) Strongylocentrotus purpuratus (Purple sea urchin) microtubule-based movement [GO:0007018] GO:0003777; GO:0005524; GO:0005737; GO:0005871; GO:0005874; GO:0007018; GO:0008017; GO:0016887 47066 XM_029340842.2 1052 498 552 1039 928 O88281 0 Multiple epidermal growth factor-like domains protein 6 (Multiple EGF-like domains protein 6) (Epidermal growth factor-like protein 3) (EGF-like protein 3) Rattus norvegicus (Rat) NA GO:0005509; GO:0005576 47067 XM_029340842.2 1052 498 552 1039 928 O88281 1.44e-177 Multiple epidermal growth factor-like domains protein 6 (Multiple EGF-like domains protein 6) (Epidermal growth factor-like protein 3) (EGF-like protein 3) Rattus norvegicus (Rat) NA GO:0005509; GO:0005576 47068 XM_029340842.2 1052 498 552 1039 928 O88281 6.51e-177 Multiple epidermal growth factor-like domains protein 6 (Multiple EGF-like domains protein 6) (Epidermal growth factor-like protein 3) (EGF-like protein 3) Rattus norvegicus (Rat) NA GO:0005509; GO:0005576 47069 XM_029340842.2 1052 498 552 1039 928 O88281 5.3e-175 Multiple epidermal growth factor-like domains protein 6 (Multiple EGF-like domains protein 6) (Epidermal growth factor-like protein 3) (EGF-like protein 3) Rattus norvegicus (Rat) NA GO:0005509; GO:0005576 47070 XM_029340842.2 1052 498 552 1039 928 O88281 2.76e-134 Multiple epidermal growth factor-like domains protein 6 (Multiple EGF-like domains protein 6) (Epidermal growth factor-like protein 3) (EGF-like protein 3) Rattus norvegicus (Rat) NA GO:0005509; GO:0005576 47071 XM_029340842.2 1052 498 552 1039 928 O88281 7.54e-73 Multiple epidermal growth factor-like domains protein 6 (Multiple EGF-like domains protein 6) (Epidermal growth factor-like protein 3) (EGF-like protein 3) Rattus norvegicus (Rat) NA GO:0005509; GO:0005576 47072 XM_029340842.2 1052 498 552 1039 928 O88281 2.29e-68 Multiple epidermal growth factor-like domains protein 6 (Multiple EGF-like domains protein 6) (Epidermal growth factor-like protein 3) (EGF-like protein 3) Rattus norvegicus (Rat) NA GO:0005509; GO:0005576 47073 XM_044325850.1 926 506 407 882 612 Q460N5 2.71e-102 Protein mono-ADP-ribosyltransferase PARP14 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (B aggressive lymphoma protein 2) (Poly [ADP-ribose] polymerase 14) (PARP-14) Homo sapiens (Human) innate immune response [GO:0045087]; negative regulation of gene expression [GO:0010629]; negative regulation of type II interferon-mediated signaling pathway [GO:0060336]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; positive regulation of interleukin-4-mediated signaling pathway [GO:1902216]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein poly-ADP-ribosylation [GO:0070212] GO:0003714; GO:0003950; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0010629; GO:0016020; GO:0016779; GO:0019899; GO:0042531; GO:0042532; GO:0045087; GO:0060336; GO:0070212; GO:0070403; GO:1902216; GO:1990404 47074 XM_044325850.1 926 506 407 882 612 Q460N5 2.33e-33 Protein mono-ADP-ribosyltransferase PARP14 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (B aggressive lymphoma protein 2) (Poly [ADP-ribose] polymerase 14) (PARP-14) Homo sapiens (Human) innate immune response [GO:0045087]; negative regulation of gene expression [GO:0010629]; negative regulation of type II interferon-mediated signaling pathway [GO:0060336]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; positive regulation of interleukin-4-mediated signaling pathway [GO:1902216]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein poly-ADP-ribosylation [GO:0070212] GO:0003714; GO:0003950; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0010629; GO:0016020; GO:0016779; GO:0019899; GO:0042531; GO:0042532; GO:0045087; GO:0060336; GO:0070212; GO:0070403; GO:1902216; GO:1990404 47075 XM_044316764.1 177 152 86 75 94 Q04721 0 Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation (N2ECD); Notch 2 intracellular domain (N2ICD)] Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; atrial septum morphogenesis [GO:0060413]; atrioventricular node development [GO:0003162]; axon guidance [GO:0007411]; BMP signaling pathway [GO:0030509]; bone remodeling [GO:0046849]; cell fate determination [GO:0001709]; cellular response to tumor cell [GO:0071228]; cholangiocyte proliferation [GO:1990705]; ciliary body morphogenesis [GO:0061073]; defense response to bacterium [GO:0042742]; embryonic limb morphogenesis [GO:0030326]; glomerular capillary formation [GO:0072104]; heart looping [GO:0001947]; hemopoiesis [GO:0030097]; hepatocyte proliferation [GO:0072574]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; intrahepatic bile duct development [GO:0035622]; left/right axis specification [GO:0070986]; marginal zone B cell differentiation [GO:0002315]; morphogenesis of an epithelial sheet [GO:0002011]; multicellular organism growth [GO:0035264]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; placenta blood vessel development [GO:0060674]; podocyte development [GO:0072015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of Ras protein signal transduction [GO:0046579]; proximal tubule development [GO:0072014]; pulmonary valve morphogenesis [GO:0003184]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of osteoclast development [GO:2001204]; wound healing [GO:0042060] GO:0000122; GO:0000139; GO:0001701; GO:0001709; GO:0001947; GO:0002011; GO:0002315; GO:0002437; GO:0003162; GO:0003184; GO:0005509; GO:0005576; GO:0005634; GO:0005654; GO:0005789; GO:0005886; GO:0005929; GO:0006915; GO:0006959; GO:0007219; GO:0007399; GO:0007411; GO:0009887; GO:0009986; GO:0010629; GO:0010838; GO:0016020; GO:0019899; GO:0030097; GO:0030326; GO:0030509; GO:0030513; GO:0035264; GO:0035622; GO:0038023; GO:0042060; GO:0042742; GO:0043011; GO:0043065; GO:0043066; GO:0043235; GO:0045672; GO:0046579; GO:0046849; GO:0051059; GO:0060413; GO:0060674; GO:0061073; GO:0061314; GO:0070374; GO:0070986; GO:0071228; GO:0072014; GO:0072015; GO:0072104; GO:0072574; GO:1990705; GO:2000249; GO:2001204 47076 XM_044316764.1 177 152 86 75 94 Q04721 0 Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation (N2ECD); Notch 2 intracellular domain (N2ICD)] Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; atrial septum morphogenesis [GO:0060413]; atrioventricular node development [GO:0003162]; axon guidance [GO:0007411]; BMP signaling pathway [GO:0030509]; bone remodeling [GO:0046849]; cell fate determination [GO:0001709]; cellular response to tumor cell [GO:0071228]; cholangiocyte proliferation [GO:1990705]; ciliary body morphogenesis [GO:0061073]; defense response to bacterium [GO:0042742]; embryonic limb morphogenesis [GO:0030326]; glomerular capillary formation [GO:0072104]; heart looping [GO:0001947]; hemopoiesis [GO:0030097]; hepatocyte proliferation [GO:0072574]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; intrahepatic bile duct development [GO:0035622]; left/right axis specification [GO:0070986]; marginal zone B cell differentiation [GO:0002315]; morphogenesis of an epithelial sheet [GO:0002011]; multicellular organism growth [GO:0035264]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; placenta blood vessel development [GO:0060674]; podocyte development [GO:0072015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of Ras protein signal transduction [GO:0046579]; proximal tubule development [GO:0072014]; pulmonary valve morphogenesis [GO:0003184]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of osteoclast development [GO:2001204]; wound healing [GO:0042060] GO:0000122; GO:0000139; GO:0001701; GO:0001709; GO:0001947; GO:0002011; GO:0002315; GO:0002437; GO:0003162; GO:0003184; GO:0005509; GO:0005576; GO:0005634; GO:0005654; GO:0005789; GO:0005886; GO:0005929; GO:0006915; GO:0006959; GO:0007219; GO:0007399; GO:0007411; GO:0009887; GO:0009986; GO:0010629; GO:0010838; GO:0016020; GO:0019899; GO:0030097; GO:0030326; GO:0030509; GO:0030513; GO:0035264; GO:0035622; GO:0038023; GO:0042060; GO:0042742; GO:0043011; GO:0043065; GO:0043066; GO:0043235; GO:0045672; GO:0046579; GO:0046849; GO:0051059; GO:0060413; GO:0060674; GO:0061073; GO:0061314; GO:0070374; GO:0070986; GO:0071228; GO:0072014; GO:0072015; GO:0072104; GO:0072574; GO:1990705; GO:2000249; GO:2001204 47077 XM_044316764.1 177 152 86 75 94 Q04721 0 Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation (N2ECD); Notch 2 intracellular domain (N2ICD)] Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; atrial septum morphogenesis [GO:0060413]; atrioventricular node development [GO:0003162]; axon guidance [GO:0007411]; BMP signaling pathway [GO:0030509]; bone remodeling [GO:0046849]; cell fate determination [GO:0001709]; cellular response to tumor cell [GO:0071228]; cholangiocyte proliferation [GO:1990705]; ciliary body morphogenesis [GO:0061073]; defense response to bacterium [GO:0042742]; embryonic limb morphogenesis [GO:0030326]; glomerular capillary formation [GO:0072104]; heart looping [GO:0001947]; hemopoiesis [GO:0030097]; hepatocyte proliferation [GO:0072574]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; intrahepatic bile duct development [GO:0035622]; left/right axis specification [GO:0070986]; marginal zone B cell differentiation [GO:0002315]; morphogenesis of an epithelial sheet [GO:0002011]; multicellular organism growth [GO:0035264]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; placenta blood vessel development [GO:0060674]; podocyte development [GO:0072015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of Ras protein signal transduction [GO:0046579]; proximal tubule development [GO:0072014]; pulmonary valve morphogenesis [GO:0003184]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of osteoclast development [GO:2001204]; wound healing [GO:0042060] GO:0000122; GO:0000139; GO:0001701; GO:0001709; GO:0001947; GO:0002011; GO:0002315; GO:0002437; GO:0003162; GO:0003184; GO:0005509; GO:0005576; GO:0005634; GO:0005654; GO:0005789; GO:0005886; GO:0005929; GO:0006915; GO:0006959; GO:0007219; GO:0007399; GO:0007411; GO:0009887; GO:0009986; GO:0010629; GO:0010838; GO:0016020; GO:0019899; GO:0030097; GO:0030326; GO:0030509; GO:0030513; GO:0035264; GO:0035622; GO:0038023; GO:0042060; GO:0042742; GO:0043011; GO:0043065; GO:0043066; GO:0043235; GO:0045672; GO:0046579; GO:0046849; GO:0051059; GO:0060413; GO:0060674; GO:0061073; GO:0061314; GO:0070374; GO:0070986; GO:0071228; GO:0072014; GO:0072015; GO:0072104; GO:0072574; GO:1990705; GO:2000249; GO:2001204 47078 XM_044316764.1 177 152 86 75 94 Q04721 2.81e-175 Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation (N2ECD); Notch 2 intracellular domain (N2ICD)] Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; atrial septum morphogenesis [GO:0060413]; atrioventricular node development [GO:0003162]; axon guidance [GO:0007411]; BMP signaling pathway [GO:0030509]; bone remodeling [GO:0046849]; cell fate determination [GO:0001709]; cellular response to tumor cell [GO:0071228]; cholangiocyte proliferation [GO:1990705]; ciliary body morphogenesis [GO:0061073]; defense response to bacterium [GO:0042742]; embryonic limb morphogenesis [GO:0030326]; glomerular capillary formation [GO:0072104]; heart looping [GO:0001947]; hemopoiesis [GO:0030097]; hepatocyte proliferation [GO:0072574]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; intrahepatic bile duct development [GO:0035622]; left/right axis specification [GO:0070986]; marginal zone B cell differentiation [GO:0002315]; morphogenesis of an epithelial sheet [GO:0002011]; multicellular organism growth [GO:0035264]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; placenta blood vessel development [GO:0060674]; podocyte development [GO:0072015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of Ras protein signal transduction [GO:0046579]; proximal tubule development [GO:0072014]; pulmonary valve morphogenesis [GO:0003184]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of osteoclast development [GO:2001204]; wound healing [GO:0042060] GO:0000122; GO:0000139; GO:0001701; GO:0001709; GO:0001947; GO:0002011; GO:0002315; GO:0002437; GO:0003162; GO:0003184; GO:0005509; GO:0005576; GO:0005634; GO:0005654; GO:0005789; GO:0005886; GO:0005929; GO:0006915; GO:0006959; GO:0007219; GO:0007399; GO:0007411; GO:0009887; GO:0009986; GO:0010629; GO:0010838; GO:0016020; GO:0019899; GO:0030097; GO:0030326; GO:0030509; GO:0030513; GO:0035264; GO:0035622; GO:0038023; GO:0042060; GO:0042742; GO:0043011; GO:0043065; GO:0043066; GO:0043235; GO:0045672; GO:0046579; GO:0046849; GO:0051059; GO:0060413; GO:0060674; GO:0061073; GO:0061314; GO:0070374; GO:0070986; GO:0071228; GO:0072014; GO:0072015; GO:0072104; GO:0072574; GO:1990705; GO:2000249; GO:2001204 47079 XM_044316764.1 177 152 86 75 94 Q04721 7.77e-160 Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation (N2ECD); Notch 2 intracellular domain (N2ICD)] Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; atrial septum morphogenesis [GO:0060413]; atrioventricular node development [GO:0003162]; axon guidance [GO:0007411]; BMP signaling pathway [GO:0030509]; bone remodeling [GO:0046849]; cell fate determination [GO:0001709]; cellular response to tumor cell [GO:0071228]; cholangiocyte proliferation [GO:1990705]; ciliary body morphogenesis [GO:0061073]; defense response to bacterium [GO:0042742]; embryonic limb morphogenesis [GO:0030326]; glomerular capillary formation [GO:0072104]; heart looping [GO:0001947]; hemopoiesis [GO:0030097]; hepatocyte proliferation [GO:0072574]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; intrahepatic bile duct development [GO:0035622]; left/right axis specification [GO:0070986]; marginal zone B cell differentiation [GO:0002315]; morphogenesis of an epithelial sheet [GO:0002011]; multicellular organism growth [GO:0035264]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; placenta blood vessel development [GO:0060674]; podocyte development [GO:0072015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of Ras protein signal transduction [GO:0046579]; proximal tubule development [GO:0072014]; pulmonary valve morphogenesis [GO:0003184]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of osteoclast development [GO:2001204]; wound healing [GO:0042060] GO:0000122; GO:0000139; GO:0001701; GO:0001709; GO:0001947; GO:0002011; GO:0002315; GO:0002437; GO:0003162; GO:0003184; GO:0005509; GO:0005576; GO:0005634; GO:0005654; GO:0005789; GO:0005886; GO:0005929; GO:0006915; GO:0006959; GO:0007219; GO:0007399; GO:0007411; GO:0009887; GO:0009986; GO:0010629; GO:0010838; GO:0016020; GO:0019899; GO:0030097; GO:0030326; GO:0030509; GO:0030513; GO:0035264; GO:0035622; GO:0038023; GO:0042060; GO:0042742; GO:0043011; GO:0043065; GO:0043066; GO:0043235; GO:0045672; GO:0046579; GO:0046849; GO:0051059; GO:0060413; GO:0060674; GO:0061073; GO:0061314; GO:0070374; GO:0070986; GO:0071228; GO:0072014; GO:0072015; GO:0072104; GO:0072574; GO:1990705; GO:2000249; GO:2001204 47080 XM_044316764.1 177 152 86 75 94 Q04721 5.03e-158 Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation (N2ECD); Notch 2 intracellular domain (N2ICD)] Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; atrial septum morphogenesis [GO:0060413]; atrioventricular node development [GO:0003162]; axon guidance [GO:0007411]; BMP signaling pathway [GO:0030509]; bone remodeling [GO:0046849]; cell fate determination [GO:0001709]; cellular response to tumor cell [GO:0071228]; cholangiocyte proliferation [GO:1990705]; ciliary body morphogenesis [GO:0061073]; defense response to bacterium [GO:0042742]; embryonic limb morphogenesis [GO:0030326]; glomerular capillary formation [GO:0072104]; heart looping [GO:0001947]; hemopoiesis [GO:0030097]; hepatocyte proliferation [GO:0072574]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; intrahepatic bile duct development [GO:0035622]; left/right axis specification [GO:0070986]; marginal zone B cell differentiation [GO:0002315]; morphogenesis of an epithelial sheet [GO:0002011]; multicellular organism growth [GO:0035264]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; placenta blood vessel development [GO:0060674]; podocyte development [GO:0072015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of Ras protein signal transduction [GO:0046579]; proximal tubule development [GO:0072014]; pulmonary valve morphogenesis [GO:0003184]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of osteoclast development [GO:2001204]; wound healing [GO:0042060] GO:0000122; GO:0000139; GO:0001701; GO:0001709; GO:0001947; GO:0002011; GO:0002315; GO:0002437; GO:0003162; GO:0003184; GO:0005509; GO:0005576; GO:0005634; GO:0005654; GO:0005789; GO:0005886; GO:0005929; GO:0006915; GO:0006959; GO:0007219; GO:0007399; GO:0007411; GO:0009887; GO:0009986; GO:0010629; GO:0010838; GO:0016020; GO:0019899; GO:0030097; GO:0030326; GO:0030509; GO:0030513; GO:0035264; GO:0035622; GO:0038023; GO:0042060; GO:0042742; GO:0043011; GO:0043065; GO:0043066; GO:0043235; GO:0045672; GO:0046579; GO:0046849; GO:0051059; GO:0060413; GO:0060674; GO:0061073; GO:0061314; GO:0070374; GO:0070986; GO:0071228; GO:0072014; GO:0072015; GO:0072104; GO:0072574; GO:1990705; GO:2000249; GO:2001204 47081 XM_044316764.1 177 152 86 75 94 Q04721 3.02e-154 Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation (N2ECD); Notch 2 intracellular domain (N2ICD)] Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; atrial septum morphogenesis [GO:0060413]; atrioventricular node development [GO:0003162]; axon guidance [GO:0007411]; BMP signaling pathway [GO:0030509]; bone remodeling [GO:0046849]; cell fate determination [GO:0001709]; cellular response to tumor cell [GO:0071228]; cholangiocyte proliferation [GO:1990705]; ciliary body morphogenesis [GO:0061073]; defense response to bacterium [GO:0042742]; embryonic limb morphogenesis [GO:0030326]; glomerular capillary formation [GO:0072104]; heart looping [GO:0001947]; hemopoiesis [GO:0030097]; hepatocyte proliferation [GO:0072574]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; intrahepatic bile duct development [GO:0035622]; left/right axis specification [GO:0070986]; marginal zone B cell differentiation [GO:0002315]; morphogenesis of an epithelial sheet [GO:0002011]; multicellular organism growth [GO:0035264]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; placenta blood vessel development [GO:0060674]; podocyte development [GO:0072015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of Ras protein signal transduction [GO:0046579]; proximal tubule development [GO:0072014]; pulmonary valve morphogenesis [GO:0003184]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of osteoclast development [GO:2001204]; wound healing [GO:0042060] GO:0000122; GO:0000139; GO:0001701; GO:0001709; GO:0001947; GO:0002011; GO:0002315; GO:0002437; GO:0003162; GO:0003184; GO:0005509; GO:0005576; GO:0005634; GO:0005654; GO:0005789; GO:0005886; GO:0005929; GO:0006915; GO:0006959; GO:0007219; GO:0007399; GO:0007411; GO:0009887; GO:0009986; GO:0010629; GO:0010838; GO:0016020; GO:0019899; GO:0030097; GO:0030326; GO:0030509; GO:0030513; GO:0035264; GO:0035622; GO:0038023; GO:0042060; GO:0042742; GO:0043011; GO:0043065; GO:0043066; GO:0043235; GO:0045672; GO:0046579; GO:0046849; GO:0051059; GO:0060413; GO:0060674; GO:0061073; GO:0061314; GO:0070374; GO:0070986; GO:0071228; GO:0072014; GO:0072015; GO:0072104; GO:0072574; GO:1990705; GO:2000249; GO:2001204 47082 XM_044316764.1 177 152 86 75 94 Q04721 3.71e-101 Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation (N2ECD); Notch 2 intracellular domain (N2ICD)] Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; atrial septum morphogenesis [GO:0060413]; atrioventricular node development [GO:0003162]; axon guidance [GO:0007411]; BMP signaling pathway [GO:0030509]; bone remodeling [GO:0046849]; cell fate determination [GO:0001709]; cellular response to tumor cell [GO:0071228]; cholangiocyte proliferation [GO:1990705]; ciliary body morphogenesis [GO:0061073]; defense response to bacterium [GO:0042742]; embryonic limb morphogenesis [GO:0030326]; glomerular capillary formation [GO:0072104]; heart looping [GO:0001947]; hemopoiesis [GO:0030097]; hepatocyte proliferation [GO:0072574]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; intrahepatic bile duct development [GO:0035622]; left/right axis specification [GO:0070986]; marginal zone B cell differentiation [GO:0002315]; morphogenesis of an epithelial sheet [GO:0002011]; multicellular organism growth [GO:0035264]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; placenta blood vessel development [GO:0060674]; podocyte development [GO:0072015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of Ras protein signal transduction [GO:0046579]; proximal tubule development [GO:0072014]; pulmonary valve morphogenesis [GO:0003184]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of osteoclast development [GO:2001204]; wound healing [GO:0042060] GO:0000122; GO:0000139; GO:0001701; GO:0001709; GO:0001947; GO:0002011; GO:0002315; GO:0002437; GO:0003162; GO:0003184; GO:0005509; GO:0005576; GO:0005634; GO:0005654; GO:0005789; GO:0005886; GO:0005929; GO:0006915; GO:0006959; GO:0007219; GO:0007399; GO:0007411; GO:0009887; GO:0009986; GO:0010629; GO:0010838; GO:0016020; GO:0019899; GO:0030097; GO:0030326; GO:0030509; GO:0030513; GO:0035264; GO:0035622; GO:0038023; GO:0042060; GO:0042742; GO:0043011; GO:0043065; GO:0043066; GO:0043235; GO:0045672; GO:0046579; GO:0046849; GO:0051059; GO:0060413; GO:0060674; GO:0061073; GO:0061314; GO:0070374; GO:0070986; GO:0071228; GO:0072014; GO:0072015; GO:0072104; GO:0072574; GO:1990705; GO:2000249; GO:2001204 47083 XR_003826066.2 28 9 12 28 13 NA NA NA NA NA NA 47084 XM_029334958.2 0 0 180 112 0 O35207 1.68e-22 Cyclin-dependent kinase 2-associated protein 1 (CDK2-associated protein 1) (Deleted in oral cancer 1) (DOC-1) (Putative oral cancer suppressor) Mus musculus (Mouse) cell cycle [GO:0007049]; face morphogenesis [GO:0060325]; in utero embryonic development [GO:0001701]; positive regulation of protein phosphorylation [GO:0001934] GO:0001701; GO:0001934; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0007049; GO:0048471; GO:0060325; GO:0070182 47085 XM_029355352.2 1045 2112 1000 1557 1064 NA NA NA NA NA NA 47086 XR_006395427.1 596 211 61 188 269 NA NA NA NA NA NA 47087 XM_029330690.2 1589 1333 632 1526 1068 P56377 3.36e-88 AP-1 complex subunit sigma-2 (Adaptor protein complex AP-1 subunit sigma-1B) (Adaptor-related protein complex 1 subunit sigma-1B) (Clathrin assembly protein complex 1 sigma-1B small chain) (Golgi adaptor HA1/AP1 adaptin sigma-1B subunit) (Sigma 1B subunit of AP-1 clathrin) (Sigma-adaptin 1B) (Sigma1B-adaptin) Homo sapiens (Human) intracellular protein transport [GO:0006886]; melanosome assembly [GO:1903232]; platelet dense granule organization [GO:0060155]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0005765; GO:0005769; GO:0005794; GO:0005829; GO:0005905; GO:0006886; GO:0016192; GO:0030119; GO:0030121; GO:0030659; GO:0032588; GO:0035615; GO:0043231; GO:0060155; GO:1903232 47088 XM_044319218.1 0 0 0 32 0 P70684 3.56e-47 15-hydroxyprostaglandin dehydrogenase [NAD(+)] (15-PGDH) (EC 1.1.1.141) (Eicosanoid/docosanoid dehydrogenase [NAD(+)]) (EC 1.1.1.-, EC 1.1.1.232) (Prostaglandin dehydrogenase 1) Cavia porcellus (Guinea pig) ductus arteriosus closure [GO:0097070]; female pregnancy [GO:0007565]; negative regulation of cell cycle [GO:0045786]; ovulation [GO:0030728]; parturition [GO:0007567]; prostaglandin metabolic process [GO:0006693]; regulation of prostaglandin catabolic process [GO:1905828]; thrombin-activated receptor signaling pathway [GO:0070493]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0004957; GO:0005737; GO:0006693; GO:0007179; GO:0007565; GO:0007567; GO:0016404; GO:0016616; GO:0030728; GO:0045786; GO:0051287; GO:0070403; GO:0070493; GO:0097070; GO:1905828 47089 XR_006398000.1 94 53 70 43 93 NA NA NA NA NA NA 47090 XM_029332394.2 3339 2709 1057 2745 2205 Q2HJ57 8.28e-37 Coactosin-like protein Bos taurus (Bovine) defense response to fungus [GO:0050832]; regulation of actin filament polymerization [GO:0030833] GO:0005634; GO:0005829; GO:0019899; GO:0030833; GO:0030864; GO:0050832; GO:0051015 47091 XM_044319969.1 12834 10856 3059 9588 4531 O93477 0 Adenosylhomocysteinase B (AdoHcyase B) (EC 3.13.2.1) (S-adenosyl-L-homocysteine hydrolase B) Xenopus laevis (African clawed frog) one-carbon metabolic process [GO:0006730] GO:0004013; GO:0005737; GO:0006730; GO:0051287 47092 XM_044306930.1 0 1 0 0 6 NA NA NA NA NA NA 47093 XM_044318059.1 0 0 8 0 9 NA NA NA NA NA NA 47094 XR_006392471.1 414 107 243 1673 209 NA NA NA NA NA NA 47095 XR_006395708.1 68 39 27 14 11 NA NA NA NA NA NA 47096 XM_044315458.1 262 244 270 103 62 NA NA NA NA NA NA 47097 XM_029333805.2 41 74 70 52 91 Q9XTR8 3.05e-33 Lipase ZK262.3 (EC 3.1.1.-) Caenorhabditis elegans lipid catabolic process [GO:0016042] GO:0005576; GO:0016042; GO:0016787 47098 XM_029332846.2 0 287 28 0 0 A3KCL7 2.62e-68 D-aspartate oxidase (DASOX) (DDO) (EC 1.4.3.1) Sus scrofa (Pig) aspartate catabolic process [GO:0006533]; D-amino acid catabolic process [GO:0019478] GO:0003884; GO:0005737; GO:0005777; GO:0006533; GO:0008445; GO:0019478; GO:0071949 47099 XM_029338048.2 252 97 75 195 236 NA NA NA NA NA NA 47100 XR_006393654.1 132 184 22 91 142 NA NA NA NA NA NA 47101 XM_044322710.1 30 17 32 18 36 Q96AY4 2.85e-134 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 47102 XM_044322710.1 30 17 32 18 36 Q96AY4 1.46e-124 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 47103 XM_044322710.1 30 17 32 18 36 Q96AY4 1.82e-80 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 47104 XM_044322710.1 30 17 32 18 36 Q96AY4 1.31e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 47105 XM_044306911.1 0 0 0 20 26 NA NA NA NA NA NA 47106 XM_044323761.1 517 495 527 703 511 NA NA NA NA NA NA 47107 XM_029348152.2 1603 961 719 931 1204 E2QSX5 2.76e-54 Intraflagellar transport protein 43 homolog Canis lupus familiaris (Dog) (Canis familiaris) cilium assembly [GO:0060271]; intraciliary retrograde transport [GO:0035721] GO:0005737; GO:0005856; GO:0005929; GO:0030991; GO:0035721; GO:0060271 47108 XM_044313950.1 10 1 8 12 7 NA NA NA NA NA NA 47109 XM_029327168.2 636 429 254 400 519 Q8BTS4 2.2e-142 Nuclear pore complex protein Nup54 (54 kDa nucleoporin) (Nucleoporin Nup54) Mus musculus (Mouse) mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; nuclear pore organization [GO:0006999]; nucleocytoplasmic transport [GO:0006913]; protein localization to nuclear inner membrane [GO:0036228]; protein targeting [GO:0006605]; regulation of protein import into nucleus [GO:0042306] GO:0005635; GO:0005643; GO:0006605; GO:0006607; GO:0006913; GO:0006999; GO:0017056; GO:0031965; GO:0032991; GO:0036228; GO:0042306; GO:0042802; GO:0044613; GO:0044877; GO:0051028 47110 XM_044315994.1 682 352 378 404 354 P70191 2.05e-90 TNF receptor-associated factor 5 Mus musculus (Mouse) apoptotic process [GO:0006915]; interleukin-17-mediated signaling pathway [GO:0097400]; mRNA stabilization [GO:0048255]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of JNK cascade [GO:0046330]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; signal transduction [GO:0007165]; signal transduction involved in regulation of gene expression [GO:0023019]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0005164; GO:0005813; GO:0005829; GO:0006915; GO:0007165; GO:0008270; GO:0008284; GO:0009898; GO:0023019; GO:0031625; GO:0031996; GO:0033209; GO:0035631; GO:0042802; GO:0042981; GO:0043122; GO:0043123; GO:0046330; GO:0048255; GO:0051091; GO:0051092; GO:0070534; GO:0097400 47111 XM_044325551.1 335 51 148 275 343 Q8BZ20 9.29e-77 Protein mono-ADP-ribosyltransferase PARP12 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 12) (ARTD12) (Poly [ADP-ribose] polymerase 12) (PARP-12) (Zinc finger CCCH domain-containing protein 1) Mus musculus (Mouse) protein auto-ADP-ribosylation [GO:0070213] GO:0003950; GO:0005634; GO:0016779; GO:0046872; GO:0070213; GO:0140803; GO:1990404 47112 XM_029341708.2 533 381 247 364 502 Q7TT28 1.79e-114 RNA exonuclease 1 homolog (EC 3.1.-.-) (Transcription elongation factor B polypeptide 3-binding protein 1) Mus musculus (Mouse) NA GO:0003676; GO:0004527; GO:0005634; GO:0005654; GO:0016604 47113 XM_044312609.1 26 10 0 0 1 NA NA NA NA NA NA 47114 XM_044309315.1 6 12 0 15 4 NA NA NA NA NA NA 47115 XM_044314676.1 17 41 29 36 40 NA NA NA NA NA NA 47116 XM_044310686.1 542 364 294 476 441 Q4R3J0 1.94e-129 RNA 3'-terminal phosphate cyclase (RNA cyclase) (RNA-3'-phosphate cyclase) (EC 6.5.1.4) (RNA terminal phosphate cyclase domain-containing protein 1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) RNA processing [GO:0006396] GO:0003963; GO:0005524; GO:0005654; GO:0006396 47117 XM_044308629.1 78 46 68 66 187 NA NA NA NA NA NA 47118 XR_003826300.2 613 593 425 456 434 NA NA NA NA NA NA 47119 XM_029348722.2 1945 1914 1053 1466 1347 NA NA NA NA NA NA 47120 XM_044315331.1 26 12 23 81 1 NA NA NA NA NA NA 47121 XM_044315239.1 559 474 362 538 217 NA NA NA NA NA NA 47122 XM_044306897.1 778 197 488 186 204 NA NA NA NA NA NA 47123 XM_044313228.1 244 172 150 238 179 P54315 1.04e-63 Inactive pancreatic lipase-related protein 1 (PL-RP1) Homo sapiens (Human) lipid metabolic process [GO:0006629] GO:0004806; GO:0005509; GO:0005576; GO:0006629 47124 XM_044324904.1 14 219 0 0 0 Q9UQ26 2.13e-62 Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2) (Rab-3-interacting protein 3) Homo sapiens (Human) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-ion regulated exocytosis [GO:0017156]; cell differentiation [GO:0030154]; insulin secretion [GO:0030073]; intracellular protein transport [GO:0006886]; positive regulation of dendrite extension [GO:1903861]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of synaptic transmission [GO:0050806]; regulation of exocytosis [GO:0017157]; regulation of membrane potential [GO:0042391]; regulation of synaptic plasticity [GO:0048167]; spontaneous neurotransmitter secretion [GO:0061669] GO:0006886; GO:0007188; GO:0017156; GO:0017157; GO:0030073; GO:0030154; GO:0031267; GO:0042391; GO:0042734; GO:0042995; GO:0044325; GO:0046872; GO:0048167; GO:0048786; GO:0048788; GO:0048791; GO:0050806; GO:0061669; GO:0070062; GO:0097151; GO:1903861; GO:2000463 47125 XM_044324904.1 14 219 0 0 0 Q9UQ26 8.64e-31 Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2) (Rab-3-interacting protein 3) Homo sapiens (Human) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-ion regulated exocytosis [GO:0017156]; cell differentiation [GO:0030154]; insulin secretion [GO:0030073]; intracellular protein transport [GO:0006886]; positive regulation of dendrite extension [GO:1903861]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of synaptic transmission [GO:0050806]; regulation of exocytosis [GO:0017157]; regulation of membrane potential [GO:0042391]; regulation of synaptic plasticity [GO:0048167]; spontaneous neurotransmitter secretion [GO:0061669] GO:0006886; GO:0007188; GO:0017156; GO:0017157; GO:0030073; GO:0030154; GO:0031267; GO:0042391; GO:0042734; GO:0042995; GO:0044325; GO:0046872; GO:0048167; GO:0048786; GO:0048788; GO:0048791; GO:0050806; GO:0061669; GO:0070062; GO:0097151; GO:1903861; GO:2000463 47126 XM_044316216.1 467 125 251 260 257 Q6IPM2 1.36e-31 IQ domain-containing protein E Homo sapiens (Human) limb morphogenesis [GO:0035108] GO:0005929; GO:0035108; GO:0060170 47127 XM_044311061.1 12 9 3 70 5 NA NA NA NA NA NA 47128 XM_029324690.2 1008 580 345 417 434 Q9W4S1 3.23e-31 Glutaredoxin domain-containing cysteine-rich protein CG12206 Drosophila melanogaster (Fruit fly) sensory perception of sound [GO:0007605] GO:0007605 47129 XM_029346409.2 673 781 353 505 442 Q4P4Y2 3.17e-61 Mitochondrial genome maintenance protein MGM101 Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus) interstrand cross-link repair [GO:0036297]; mitochondrial genome maintenance [GO:0000002]; recombinational repair [GO:0000725] GO:0000002; GO:0000262; GO:0000725; GO:0003677; GO:0003697; GO:0036297; GO:0042645 47130 XM_029338175.2 104 251 198 217 97 NA NA NA NA NA NA 47131 XM_044307318.1 0 0 0 55 0 Q9Y3Q0 2.31e-51 N-acetylated-alpha-linked acidic dipeptidase 2 (EC 3.4.17.21) (Glutamate carboxypeptidase III) (GCPIII) (N-acetylated-alpha-linked acidic dipeptidase II) (NAALADase II) Homo sapiens (Human) proteolysis [GO:0006508] GO:0004180; GO:0004181; GO:0005886; GO:0006508; GO:0008236; GO:0008239; GO:0016020; GO:0016805; GO:0046872 47132 XM_044307318.1 0 0 0 55 0 Q9Y3Q0 2.31e-51 N-acetylated-alpha-linked acidic dipeptidase 2 (EC 3.4.17.21) (Glutamate carboxypeptidase III) (GCPIII) (N-acetylated-alpha-linked acidic dipeptidase II) (NAALADase II) Homo sapiens (Human) proteolysis [GO:0006508] GO:0004180; GO:0004181; GO:0005886; GO:0006508; GO:0008236; GO:0008239; GO:0016020; GO:0016805; GO:0046872 47133 XM_044307857.1 0 102 50 10 0 NA NA NA NA NA NA 47134 XM_044310944.1 36 68 63 47 139 P0CT40 3.26e-86 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 47135 XM_044320361.1 6 16 33 45 30 NA NA NA NA NA NA 47136 XM_044312678.1 7 1 26 11 52 NA NA NA NA NA NA 47137 XM_044324766.1 0 7 0 0 0 Q96RW7 1.74e-63 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 47138 XM_044324766.1 0 7 0 0 0 Q96RW7 2.65e-54 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 47139 XM_044324766.1 0 7 0 0 0 Q96RW7 4.54e-54 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 47140 XM_044324766.1 0 7 0 0 0 Q96RW7 1.12e-52 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 47141 XM_044324766.1 0 7 0 0 0 Q96RW7 4.67e-52 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 47142 XM_044324766.1 0 7 0 0 0 Q96RW7 2.49e-49 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 47143 XM_044324766.1 0 7 0 0 0 Q96RW7 1.41e-47 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 47144 XM_044324766.1 0 7 0 0 0 Q96RW7 2.38e-44 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 47145 XM_044324766.1 0 7 0 0 0 Q96RW7 2.87e-41 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 47146 XM_044324766.1 0 7 0 0 0 Q96RW7 9.47e-40 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 47147 XM_044324766.1 0 7 0 0 0 Q96RW7 2.33e-35 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 47148 XR_006391827.1 7 23 1 1 6 NA NA NA NA NA NA 47149 XM_029356762.2 3653 2999 2132 3275 2187 NA NA NA NA NA NA 47150 XM_044314979.1 18 43 59 19 137 NA NA NA NA NA NA 47151 XM_029324143.2 1 0 0 0 9 NA NA NA NA NA NA 47152 XM_029351448.2 14958 14721 10188 15470 10603 Q5RE11 2.38e-22 Tetraspanin-3 (Tspan-3) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0016020 47153 XM_044314955.1 23 56 14 79 0 NA NA NA NA NA NA 47154 XM_044319396.1 0 0 1 0 57 NA NA NA NA NA NA 47155 XM_029343038.2 51 7 36 20 84 NA NA NA NA NA NA 47156 XM_029341589.2 333 75 78 88 192 Q8NBS3 2.46e-178 Solute carrier family 4 member 11 (Sodium borate cotransporter 1) (NaBC1) Homo sapiens (Human) bicarbonate transport [GO:0015701]; borate transport [GO:0046713]; cellular cation homeostasis [GO:0030003]; cellular hypotonic response [GO:0071476]; cellular response to oxidative stress [GO:0034599]; fluid transport [GO:0042044]; ion homeostasis [GO:0050801]; proton transmembrane transport [GO:1902600]; regulation of mesenchymal stem cell differentiation [GO:2000739]; regulation of mitochondrial membrane potential [GO:0051881]; sodium ion transport [GO:0006814]; transmembrane transport [GO:0055085] GO:0005272; GO:0005372; GO:0005452; GO:0005886; GO:0006814; GO:0012506; GO:0015078; GO:0015106; GO:0015252; GO:0015293; GO:0015701; GO:0016323; GO:0016324; GO:0022857; GO:0030003; GO:0034599; GO:0042044; GO:0046713; GO:0046715; GO:0046983; GO:0050801; GO:0051881; GO:0055085; GO:0071476; GO:1902600; GO:2000739 47157 XM_044307577.1 173 280 53 59 138 Q497B8 5.74e-22 Bifunctional peptidase and arginyl-hydroxylase JMJD5 (EC 1.14.11.73) (EC 3.4.-.-) (JmjC domain-containing protein 5) (Jumonji C domain-containing protein 5) (L-arginine (3R)-hydroxylase KDM8) Rattus norvegicus (Rat) chromatin organization [GO:0006325]; circadian regulation of gene expression [GO:0032922]; G2/M transition of mitotic cell cycle [GO:0000086]; histone H3-K36 demethylation [GO:0070544]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of DNA-templated transcription [GO:0045893]; protein destabilization [GO:0031648]; proteolysis [GO:0006508] GO:0000086; GO:0003682; GO:0004175; GO:0004177; GO:0005634; GO:0005694; GO:0006325; GO:0006508; GO:0016706; GO:0031648; GO:0032922; GO:0035064; GO:0045892; GO:0045893; GO:0046872; GO:0051864; GO:0070544; GO:0106157 47158 XR_006394192.1 33 147 8 138 25 NA NA NA NA NA NA 47159 XR_006395895.1 29 18 56 33 51 Q3ZC26 3.15e-22 Sodium/myo-inositol cotransporter 2 (Na(+)/myo-inositol cotransporter 2) (Sodium/myo-inositol transporter 2) (SMIT2) (Solute carrier family 5 member 11) Bos taurus (Bovine) apoptotic process [GO:0006915]; myo-inositol transport [GO:0015798] GO:0005365; GO:0005412; GO:0005886; GO:0006915; GO:0015798; GO:0016020; GO:0016324 47160 XM_044310525.1 0 1 12 0 1 NA NA NA NA NA NA 47161 XR_003825437.2 141 49 8 76 96 NA NA NA NA NA NA 47162 XM_029341634.2 3056 2454 891 1114 1435 NA NA NA NA NA NA 47163 XM_029327689.2 0 7 1 30 35 NA NA NA NA NA NA 47164 XM_044314482.1 1335 0 1 0 559 Q9NZJ4 0 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 47165 XM_044314482.1 1335 0 1 0 559 Q9NZJ4 2.6e-52 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 47166 XM_044314482.1 1335 0 1 0 559 Q9NZJ4 1.16e-42 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 47167 XM_044314482.1 1335 0 1 0 559 Q9NZJ4 2.53e-41 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 47168 XM_029357139.2 28 20 6 22 27 NA NA NA NA NA NA 47169 XR_006397048.1 161 191 125 160 184 NA NA NA NA NA NA 47170 XM_044308755.1 825 681 223 849 472 Q8IXR9 5.31e-58 Uncharacterized protein C12orf56 Homo sapiens (Human) NA NA 47171 XM_044312862.1 335 186 104 359 240 Q6AXS0 6.65e-100 Mitochondrial sodium/calcium exchanger protein (Na(+)/K(+)/Ca(2+)-exchange protein 6) (Sodium/calcium exchanger protein, mitochondrial) (Sodium/potassium/calcium exchanger 6) (Solute carrier family 24 member 6) (Solute carrier family 8 member B1) Rattus norvegicus (Rat) calcium export from the mitochondrion [GO:0099093]; calcium ion transmembrane transport [GO:0070588]; cation transport [GO:0006812]; cellular calcium ion homeostasis [GO:0006874]; glucose homeostasis [GO:0042593]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrial calcium ion transmembrane transport [GO:0006851]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of insulin secretion [GO:0050796]; regulation of lymphocyte chemotaxis [GO:1901623]; regulation of store-operated calcium entry [GO:2001256]; response to stimulus [GO:0050896]; sodium ion transmembrane transport [GO:0035725] GO:0005432; GO:0005739; GO:0005743; GO:0005886; GO:0006812; GO:0006851; GO:0006874; GO:0008324; GO:0016020; GO:0030061; GO:0031966; GO:0035725; GO:0042383; GO:0042593; GO:0042802; GO:0042803; GO:0050796; GO:0050896; GO:0051480; GO:0051560; GO:0070588; GO:0086038; GO:0099093; GO:1901623; GO:2001256 47172 XM_029357445.2 69831 98901 42097 83397 52024 P54864 2.04e-34 Transcription factor Jun (Proto-oncogene c-Jun) (Transcription factor AP-1 subunit Jun) Serinus canaria (Island canary) (Fringilla canaria) positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000976; GO:0003700; GO:0005634; GO:0045944 47173 XM_029334641.2 1902 671 725 1602 1571 Q69Z28 8.27e-107 A disintegrin and metalloproteinase with thrombospondin motifs 16 (ADAM-TS 16) (ADAM-TS16) (ADAMTS-16) (EC 3.4.24.-) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; extracellular matrix organization [GO:0030198]; male gamete generation [GO:0048232]; proteolysis [GO:0006508]; regulation of cilium assembly [GO:1902017]; regulation of systemic arterial blood pressure [GO:0003073] GO:0001658; GO:0003073; GO:0004222; GO:0005576; GO:0006508; GO:0030198; GO:0031012; GO:0046872; GO:0048232; GO:1902017 47174 XM_044314828.1 0 0 49 29 17 NA NA NA NA NA NA 47175 XM_029346814.2 2 4 7 4 36 NA NA NA NA NA NA 47176 XM_044323561.1 927 515 424 641 981 O08810 0 116 kDa U5 small nuclear ribonucleoprotein component (Elongation factor Tu GTP-binding domain-containing protein 2) (U5 snRNP-specific protein, 116 kDa) (U5-116 kDa) Mus musculus (Mouse) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0003924; GO:0005525; GO:0005634; GO:0005654; GO:0005829; GO:0015030; GO:0016607; GO:0030623; GO:0043231; GO:0046540; GO:0071005; GO:0071007; GO:0071013; GO:1990904 47177 XM_029323714.2 1254 1119 663 1099 1425 Q6MG08 0 ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) Rattus norvegicus (Rat) positive regulation of translation [GO:0045727]; translation [GO:0006412]; translational initiation [GO:0006413] GO:0005524; GO:0005635; GO:0005654; GO:0005737; GO:0005840; GO:0006412; GO:0006413; GO:0008494; GO:0016887; GO:0042788; GO:0043022; GO:0045727 47178 XM_044318275.1 103 73 43 276 127 NA NA NA NA NA NA 47179 XM_029358237.2 94 0 0 891 0 P14543 1.62e-87 Nidogen-1 (NID-1) (Entactin) Homo sapiens (Human) basement membrane organization [GO:0071711]; cell-matrix adhesion [GO:0007160]; glomerular basement membrane development [GO:0032836]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of muscle cell differentiation [GO:0051149]; regulation of basement membrane organization [GO:0110011] GO:0005201; GO:0005509; GO:0005518; GO:0005576; GO:0005604; GO:0005886; GO:0007160; GO:0010811; GO:0032836; GO:0043236; GO:0043237; GO:0043394; GO:0045785; GO:0051149; GO:0062023; GO:0070062; GO:0071711; GO:0098637; GO:0110011; GO:2001046 47180 XM_029358237.2 94 0 0 891 0 P14543 3.46e-43 Nidogen-1 (NID-1) (Entactin) Homo sapiens (Human) basement membrane organization [GO:0071711]; cell-matrix adhesion [GO:0007160]; glomerular basement membrane development [GO:0032836]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of muscle cell differentiation [GO:0051149]; regulation of basement membrane organization [GO:0110011] GO:0005201; GO:0005509; GO:0005518; GO:0005576; GO:0005604; GO:0005886; GO:0007160; GO:0010811; GO:0032836; GO:0043236; GO:0043237; GO:0043394; GO:0045785; GO:0051149; GO:0062023; GO:0070062; GO:0071711; GO:0098637; GO:0110011; GO:2001046 47181 XM_029358237.2 94 0 0 891 0 P14543 3.96e-22 Nidogen-1 (NID-1) (Entactin) Homo sapiens (Human) basement membrane organization [GO:0071711]; cell-matrix adhesion [GO:0007160]; glomerular basement membrane development [GO:0032836]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of muscle cell differentiation [GO:0051149]; regulation of basement membrane organization [GO:0110011] GO:0005201; GO:0005509; GO:0005518; GO:0005576; GO:0005604; GO:0005886; GO:0007160; GO:0010811; GO:0032836; GO:0043236; GO:0043237; GO:0043394; GO:0045785; GO:0051149; GO:0062023; GO:0070062; GO:0071711; GO:0098637; GO:0110011; GO:2001046 47182 XM_029331439.2 707 579 357 568 677 Q8BZ20 4.72e-102 Protein mono-ADP-ribosyltransferase PARP12 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 12) (ARTD12) (Poly [ADP-ribose] polymerase 12) (PARP-12) (Zinc finger CCCH domain-containing protein 1) Mus musculus (Mouse) protein auto-ADP-ribosylation [GO:0070213] GO:0003950; GO:0005634; GO:0016779; GO:0046872; GO:0070213; GO:0140803; GO:1990404 47183 XM_044313908.1 235 133 203 690 389 NA NA NA NA NA NA 47184 XM_029324603.2 1224 1252 763 1406 1377 Q5R941 1.7e-41 Peptidyl-prolyl cis-trans isomerase FKBP14 (PPIase FKBP14) (EC 5.2.1.8) (FK506-binding protein 14) (FKBP-14) (Rotamase) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003755; GO:0005509; GO:0005788 47185 XM_044310083.1 69 48 0 0 35 O00338 2.7e-57 Sulfotransferase 1C2 (ST1C2) (EC 2.8.2.1) (Sulfotransferase 1C1) (SULT1C#1) (humSULTC2) Homo sapiens (Human) amine metabolic process [GO:0009308]; sulfation [GO:0051923] GO:0004062; GO:0005737; GO:0005764; GO:0005829; GO:0008146; GO:0009308; GO:0051923 47186 XM_029329034.2 497 349 288 460 531 P23978 0 Sodium- and chloride-dependent GABA transporter 1 (GAT-1) (Solute carrier family 6 member 1) Rattus norvegicus (Rat) associative learning [GO:0008306]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid import [GO:0051939]; inorganic anion import across plasma membrane [GO:0098658]; learning [GO:0007612]; memory [GO:0007613]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; neurotransmitter reuptake [GO:0098810]; positive regulation of gamma-aminobutyric acid secretion [GO:0014054]; response to calcium ion [GO:0051592]; response to cocaine [GO:0042220]; response to estradiol [GO:0032355]; response to inorganic substance [GO:0010035]; response to lead ion [GO:0010288]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to organonitrogen compound [GO:0010243]; response to purine-containing compound [GO:0014074]; response to sucrose [GO:0009744]; response to toxic substance [GO:0009636]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725]; synapse organization [GO:0050808] GO:0005283; GO:0005332; GO:0005886; GO:0007612; GO:0007613; GO:0008306; GO:0009636; GO:0009744; GO:0009986; GO:0010033; GO:0010035; GO:0010243; GO:0010288; GO:0014054; GO:0014070; GO:0014074; GO:0015185; GO:0015378; GO:0030424; GO:0032229; GO:0032355; GO:0035725; GO:0042220; GO:0042734; GO:0042802; GO:0043005; GO:0043025; GO:0045211; GO:0046872; GO:0050808; GO:0051592; GO:0051939; GO:0098658; GO:0098719; GO:0098793; GO:0098810; GO:0098982; GO:1902476 47187 XM_044307046.1 0 0 84 407 0 O75445 8.75e-115 Usherin (Usher syndrome type IIa protein) (Usher syndrome type-2A protein) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear receptor cell differentiation [GO:0060113]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0001917; GO:0002141; GO:0002142; GO:0005518; GO:0005576; GO:0005604; GO:0005737; GO:0007601; GO:0007605; GO:0009887; GO:0009888; GO:0016324; GO:0016477; GO:0017022; GO:0032391; GO:0032421; GO:0034446; GO:0035315; GO:0036064; GO:0042491; GO:0042802; GO:0045184; GO:0045494; GO:0048496; GO:0050896; GO:0050953; GO:0051649; GO:0060113; GO:0060171; GO:1990075; GO:1990696 47188 XM_044322946.1 873 390 0 0 0 O14036 3.19e-50 Small nuclear ribonucleoprotein Sm D2 (Sm-D2) (Complexed with cdc5 protein 9) (snRNP core protein D2) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) mRNA 5'-splice site recognition [GO:0000395]; spliceosomal snRNP assembly [GO:0000387] GO:0000387; GO:0000395; GO:0000974; GO:0005634; GO:0005681; GO:0005682; GO:0005685; GO:0005686; GO:0005829; GO:0046540; GO:0071004; GO:0071011; GO:0071013; GO:0071014 47189 XR_006395078.1 81 14 25 39 75 NA NA NA NA NA NA 47190 XM_029345446.2 6 52 0 0 36 NA NA NA NA NA NA 47191 XM_029355048.2 502 676 312 426 412 B5X4E0 1.9e-72 Calumenin-B Salmo salar (Atlantic salmon) NA GO:0005509; GO:0005576; GO:0005789; GO:0005794; GO:0033018; GO:0042470 47192 XM_029329151.2 131 262 148 329 383 NA NA NA NA NA NA 47193 XM_044324178.1 6 0 0 0 0 NA NA NA NA NA NA 47194 XM_044325642.1 0 18 0 27 20 NA NA NA NA NA NA 47195 XR_006394667.1 6 0 9 2 15 P26714 3.48e-52 Gamma-aminobutyric acid receptor subunit beta (GABA(A) receptor) Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004890; GO:0005230; GO:0005254; GO:0034707; GO:0045211 47196 XR_006394667.1 6 0 9 2 15 P26714 3.48e-52 Gamma-aminobutyric acid receptor subunit beta (GABA(A) receptor) Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004890; GO:0005230; GO:0005254; GO:0034707; GO:0045211 47197 XM_044317445.1 284 34 61 135 72 O62852 4.95e-60 Short transient receptor potential channel 5 (Rtrp5) (TrpC5) (Capacitative calcium entry channel 2) (CCE2) Oryctolagus cuniculus (Rabbit) neuron apoptotic process [GO:0051402]; phosphatidylserine exposure on apoptotic cell surface [GO:0070782] GO:0005262; GO:0005886; GO:0034704; GO:0051402; GO:0070679; GO:0070782 47198 XR_003824658.2 169 130 104 262 268 NA NA NA NA NA NA 47199 XM_044326283.1 0 0 16 17 72 NA NA NA NA NA NA 47200 XR_006395385.1 10 2 0 10 0 NA NA NA NA NA NA 47201 XM_044321012.1 907 605 392 673 1020 F1QF89 0 Protein O-mannosyl-transferase 1 (EC 2.4.1.109) Danio rerio (Zebrafish) (Brachydanio rerio) protein O-linked mannosylation [GO:0035269] GO:0004169; GO:0005783; GO:0005789; GO:0035269 47202 XM_044320848.1 566 329 334 656 844 Q9H720 0 PGAP2-interacting protein (Cell wall biogenesis protein 43 C-terminal homolog) Homo sapiens (Human) GPI anchor biosynthetic process [GO:0006506] GO:0005783; GO:0006506; GO:0016020 47203 XM_029352889.2 21 22 0 6 8 NA NA NA NA NA NA 47204 XR_006397914.1 193 41 97 61 141 NA NA NA NA NA NA 47205 XM_029346549.2 1482 1204 497 662 849 Q5U2Q4 6.14e-94 Protein mono-ADP-ribosyltransferase PARP16 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 15) (Poly [ADP-ribose] polymerase 16) (PARP-16) Rattus norvegicus (Rat) cellular response to leukemia inhibitory factor [GO:1990830]; endoplasmic reticulum unfolded protein response [GO:0030968]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of cell death [GO:0060548]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein auto-ADP-ribosylation [GO:0070213] GO:0003950; GO:0005635; GO:0005783; GO:0005789; GO:0016779; GO:0019900; GO:0030968; GO:0036498; GO:0043539; GO:0060548; GO:0070213; GO:0071782; GO:0071902; GO:0140804; GO:0140806; GO:0140807; GO:1990404; GO:1990830 47206 XM_044323066.1 99 111 56 62 102 NA NA NA NA NA NA 47207 XR_006394504.1 0 0 7 0 6 NA NA NA NA NA NA 47208 XM_029335667.2 594 989 541 888 549 F1MA98 0 Nucleoprotein TPR (Megator) (NPC-associated intranuclear protein) (Translocated promoter region protein) Rattus norvegicus (Rat) cell division [GO:0051301]; cellular response to heat [GO:0034605]; cellular response to interferon-alpha [GO:0035457]; mitotic spindle assembly checkpoint signaling [GO:0007094]; mRNA export from nucleus [GO:0006406]; mRNA export from nucleus in response to heat stress [GO:0031990]; negative regulation of RNA export from nucleus [GO:0046832]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of translational initiation [GO:0045947]; nuclear pore organization [GO:0006999]; positive regulation of heterochromatin formation [GO:0031453]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; regulation of mitotic sister chromatid separation [GO:0010965]; regulation of mitotic spindle assembly [GO:1901673]; regulation of protein localization [GO:0032880]; response to epidermal growth factor [GO:0070849]; RNA export from nucleus [GO:0006405]; RNA import into nucleus [GO:0006404] GO:0000122; GO:0000776; GO:0003682; GO:0003729; GO:0005634; GO:0005635; GO:0005643; GO:0005737; GO:0005868; GO:0006404; GO:0006405; GO:0006406; GO:0006606; GO:0006611; GO:0006999; GO:0007094; GO:0010965; GO:0015631; GO:0017056; GO:0019898; GO:0031072; GO:0031453; GO:0031965; GO:0031990; GO:0032880; GO:0034399; GO:0034605; GO:0035457; GO:0042307; GO:0042405; GO:0042803; GO:0044615; GO:0045947; GO:0046827; GO:0046832; GO:0051019; GO:0051301; GO:0070840; GO:0070849; GO:0072686; GO:0090267; GO:0090316; GO:1901673 47209 XM_044311632.1 4 7 5 20 46 NA NA NA NA NA NA 47210 XM_044311700.1 2418 1727 1539 2519 2190 Q9PVK2 0 Alpha-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (Phosphopyruvate hydratase) Alligator mississippiensis (American alligator) glycolytic process [GO:0006096] GO:0000015; GO:0000287; GO:0004634; GO:0006096 47211 XM_029341152.2 670 430 212 327 386 Q9H1D0 1.94e-53 Transient receptor potential cation channel subfamily V member 6 (TrpV6) (CaT-like) (CaT-L) (Calcium transport protein 1) (CaT1) (Epithelial calcium channel 2) (ECaC2) Homo sapiens (Human) calcium ion homeostasis [GO:0055074]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; parathyroid hormone secretion [GO:0035898]; regulation of calcium ion-dependent exocytosis [GO:0017158]; response to calcium ion [GO:0051592] GO:0005216; GO:0005262; GO:0005516; GO:0005886; GO:0006816; GO:0017158; GO:0034704; GO:0035898; GO:0042802; GO:0046872; GO:0051592; GO:0055074; GO:0070588; GO:0098703 47212 XM_044315185.1 7 0 15 0 0 NA NA NA NA NA NA 47213 XM_044313332.1 109 58 210 134 103 NA NA NA NA NA NA 47214 XM_029347512.2 0 0 0 0 73 NA NA NA NA NA NA 47215 XR_003827579.2 10 0 1 0 0 NA NA NA NA NA NA 47216 XR_006397405.1 97 155 496 47 234 NA NA NA NA NA NA 47217 XR_006395315.1 1 0 3 16 25 Q9W0A0 1.82e-21 Protein draper Drosophila melanogaster (Fruit fly) apoptotic cell clearance [GO:0043277]; cell competition in a multicellular organism [GO:0035212]; defense response to bacterium [GO:0042742]; engulfment of apoptotic cell [GO:0043652]; hydrogen peroxide mediated signaling pathway [GO:0071588]; larval locomotory behavior [GO:0008345]; neuron remodeling [GO:0016322]; phagocytosis [GO:0006909]; phagocytosis, engulfment [GO:0006911]; positive regulation of inflammatory response to wounding [GO:0106016]; positive regulation of phagocytosis, engulfment [GO:0060100]; regulation of neuromuscular junction development [GO:1904396]; response to axon injury [GO:0048678]; salivary gland cell autophagic cell death [GO:0035071]; wing disc dorsal/ventral pattern formation [GO:0048190] GO:0001786; GO:0001891; GO:0005044; GO:0005737; GO:0005886; GO:0005938; GO:0006909; GO:0006911; GO:0008345; GO:0016020; GO:0016322; GO:0030424; GO:0035071; GO:0035212; GO:0042742; GO:0043277; GO:0043652; GO:0045211; GO:0045335; GO:0048190; GO:0048678; GO:0060100; GO:0071588; GO:0098794; GO:0106016; GO:1904396 47218 XM_044319197.1 44 12 55 36 27 NA NA NA NA NA NA 47219 XM_044317993.1 1960 1720 1028 1821 1731 Q7ZVM1 0 WASH complex subunit 5 (WASH complex subunit strumpellin) Danio rerio (Zebrafish) (Brachydanio rerio) actin filament polymerization [GO:0030041]; axonogenesis [GO:0007409]; endosome fission [GO:0140285]; endosome organization [GO:0007032]; heart contraction [GO:0060047]; neuron development [GO:0048666]; protein transport [GO:0015031]; regulation of actin nucleation [GO:0051125] GO:0005768; GO:0005769; GO:0007032; GO:0007409; GO:0015031; GO:0030041; GO:0048666; GO:0051125; GO:0060047; GO:0071203; GO:0140285 47220 XM_029337164.2 0 0 6 13 0 NA NA NA NA NA NA 47221 XM_029352880.2 0 0 6 0 0 NA NA NA NA NA NA 47222 XM_044310993.1 33 0 0 0 0 NA NA NA NA NA NA 47223 XM_044321994.1 0 0 7 0 0 A2VDD2 1.08e-23 Dynein light chain Tctex-type 5-B (Tctex1 domain-containing protein 1-B) Xenopus laevis (African clawed frog) NA NA 47224 XR_006396866.1 104 24 19 48 31 NA NA NA NA NA NA 47225 XR_003825829.2 284 66 39 108 83 NA NA NA NA NA NA 47226 XM_044307489.1 8 20 3 11 23 P79385 1.24e-21 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (SED1) (Sperm surface protein SP47) (PP47) Sus scrofa (Pig) angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; single fertilization [GO:0007338] GO:0001525; GO:0002080; GO:0005576; GO:0007155; GO:0007338 47227 XR_006392117.1 37 53 11 36 17 NA NA NA NA NA NA 47228 XM_044310137.1 13 8 43 4 22 Q3UQ28 8.47e-32 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 47229 XM_044310137.1 13 8 43 4 22 Q3UQ28 6.64e-31 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 47230 XM_044327663.1 0 90 82 119 82 NA NA NA NA NA NA 47231 XM_029354750.2 8 0 0 0 0 NA NA NA NA NA NA 47232 XR_003826941.2 210 703 31 26 36 NA NA NA NA NA NA 47233 XM_029323715.2 4001 2484 2687 4184 4261 P05556 2.92e-157 Integrin beta-1 (Fibronectin receptor subunit beta) (Glycoprotein IIa) (GPIIA) (VLA-4 subunit beta) (CD antigen CD29) Homo sapiens (Human) axon extension [GO:0048675]; B cell differentiation [GO:0030183]; basement membrane organization [GO:0071711]; calcium-independent cell-matrix adhesion [GO:0007161]; cardiac cell fate specification [GO:0060912]; cardiac muscle cell differentiation [GO:0055007]; cardiac muscle cell myoblast differentiation [GO:0060379]; CD40 signaling pathway [GO:0023035]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell migration [GO:0016477]; cell migration involved in sprouting angiogenesis [GO:0002042]; cell projection organization [GO:0030030]; cell-cell adhesion mediated by integrin [GO:0033631]; cell-matrix adhesion [GO:0007160]; cell-substrate adhesion [GO:0031589]; cellular defense response [GO:0006968]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; dendrite morphogenesis [GO:0048813]; establishment of mitotic spindle orientation [GO:0000132]; formation of radial glial scaffolds [GO:0021943]; G1/S transition of mitotic cell cycle [GO:0000082]; germ cell migration [GO:0008354]; heterotypic cell-cell adhesion [GO:0034113]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; integrin-mediated signaling pathway [GO:0007229]; lamellipodium assembly [GO:0030032]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte tethering or rolling [GO:0050901]; maintenance of blood-brain barrier [GO:0035633]; mesodermal cell differentiation [GO:0048333]; muscle organ development [GO:0007517]; myoblast differentiation [GO:0045445]; myoblast fate specification [GO:0048626]; myoblast fusion [GO:0007520]; negative regulation of anoikis [GO:2000811]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of Rho protein signal transduction [GO:0035024]; neuroblast proliferation [GO:0007405]; phagocytosis [GO:0006909]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration [GO:0030335]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of glutamate uptake involved in transmission of nerve impulse [GO:0051951]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of wound healing [GO:0090303]; reactive gliosis [GO:0150103]; receptor internalization [GO:0031623]; regulation of cell cycle [GO:0051726]; regulation of collagen catabolic process [GO:0010710]; regulation of inward rectifier potassium channel activity [GO:1901979]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synapse pruning [GO:1905806]; sarcomere organization [GO:0045214]; visual learning [GO:0008542]; wound healing, spreading of epidermal cells [GO:0035313] GO:0000082; GO:0000132; GO:0001618; GO:0001701; GO:0001726; GO:0001968; GO:0002020; GO:0002042; GO:0002052; GO:0003779; GO:0005178; GO:0005737; GO:0005886; GO:0005925; GO:0006909; GO:0006968; GO:0007155; GO:0007156; GO:0007159; GO:0007160; GO:0007161; GO:0007229; GO:0007405; GO:0007517; GO:0007520; GO:0008354; GO:0008542; GO:0009897; GO:0009986; GO:0010008; GO:0010710; GO:0010763; GO:0014704; GO:0015026; GO:0016020; GO:0016477; GO:0021943; GO:0023035; GO:0030027; GO:0030030; GO:0030032; GO:0030175; GO:0030183; GO:0030335; GO:0031589; GO:0031594; GO:0031623; GO:0032154; GO:0032587; GO:0033627; GO:0033631; GO:0034113; GO:0034665; GO:0034666; GO:0034667; GO:0034668; GO:0034674; GO:0034677; GO:0034678; GO:0034680; GO:0034681; GO:0035024; GO:0035313; GO:0035633; GO:0035748; GO:0042383; GO:0042470; GO:0043065; GO:0043197; GO:0043235; GO:0043236; GO:0043547; GO:0044877; GO:0045121; GO:0045214; GO:0045296; GO:0045445; GO:0045665; GO:0045766; GO:0046872; GO:0046982; GO:0048333; GO:0048471; GO:0048626; GO:0048675; GO:0048813; GO:0050839; GO:0050901; GO:0051726; GO:0051897; GO:0051951; GO:0055007; GO:0055037; GO:0060379; GO:0060912; GO:0070062; GO:0071404; GO:0071711; GO:0090303; GO:0097060; GO:0097386; GO:0098639; GO:0098685; GO:0150003; GO:0150053; GO:0150103; GO:1901979; GO:1903078; GO:1905806; GO:1990782; GO:2000273; GO:2000811 47234 XM_044323242.1 16 0 39 10 140 NA NA NA NA NA NA 47235 XM_029345156.2 93 927 0 2099 1498 Q5ZL74 1.86e-90 Vesicle-associated membrane protein 7 (Synaptobrevin-like protein 1) Gallus gallus (Chicken) calcium-ion regulated exocytosis [GO:0017156]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endosome to lysosome transport [GO:0008333]; eosinophil degranulation [GO:0043308]; exocytosis [GO:0006887]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; protein transport [GO:0015031]; vesicle fusion [GO:0006906]; vesicle-mediated transport [GO:0016192] GO:0000149; GO:0005484; GO:0005765; GO:0005789; GO:0005794; GO:0006887; GO:0006888; GO:0006906; GO:0006911; GO:0008333; GO:0015031; GO:0016192; GO:0017156; GO:0030658; GO:0030670; GO:0031201; GO:0031902; GO:0043005; GO:0043308; GO:0043312; GO:0045202; GO:0045335 47236 XM_029340692.2 49 258 124 117 47 A4FUY7 9.39e-61 Molybdopterin synthase catalytic subunit (EC 2.8.1.12) (Molybdenum cofactor synthesis protein 2 large subunit) (Molybdenum cofactor synthesis protein 2B) (MOCS2B) Bos taurus (Bovine) Mo-molybdopterin cofactor biosynthetic process [GO:0006777] GO:0005829; GO:0006777; GO:0016607; GO:0019008; GO:0030366 47237 XM_029335171.2 40 18 28 38 26 O43184 6.29e-122 Disintegrin and metalloproteinase domain-containing protein 12 (ADAM 12) (EC 3.4.24.-) (Meltrin-alpha) Homo sapiens (Human) cell adhesion [GO:0007155]; myoblast fusion [GO:0007520]; positive regulation of angiogenesis [GO:0045766]; proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0005654; GO:0005886; GO:0006508; GO:0007155; GO:0007520; GO:0008237; GO:0017124; GO:0045766; GO:0046872 47238 XM_029328489.2 144 80 72 192 189 O73853 1.92e-126 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Ictalurus punctatus (Channel catfish) (Silurus punctatus) steroid biosynthetic process [GO:0006694] GO:0004508; GO:0005506; GO:0006694; GO:0016020; GO:0020037; GO:0047442 47239 XR_003828463.2 18 2 8 21 18 NA NA NA NA NA NA 47240 XM_029340237.2 2299 2000 1550 3559 2996 NA NA NA NA NA NA 47241 XM_044311393.1 421 965 378 460 608 NA NA NA NA NA NA 47242 XM_029328572.2 100 0 64 147 97 NA NA NA NA NA NA 47243 XM_044327897.1 30 3 0 21 18 NA NA NA NA NA NA 47244 XM_044309656.1 3713 2861 2175 3435 3171 Q11076 3.42e-61 Probable ubiquitin-conjugating enzyme protein 17 Caenorhabditis elegans negative regulation of apoptotic process [GO:0043066] GO:0004869; GO:0005634; GO:0016874; GO:0043066; GO:0061631 47245 XR_006393060.1 41 2 25 5 151 NA NA NA NA NA NA 47246 XM_044325769.1 8 23 0 17 36 P33450 7.13e-31 Cadherin-related tumor suppressor (Protein fat) [Cleaved into: Ft-mito] Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; equator specification [GO:0045317]; establishment of body hair planar orientation [GO:0048105]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; establishment or maintenance of polarity of larval imaginal disc epithelium [GO:0016336]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; imaginal disc-derived wing morphogenesis [GO:0007476]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of growth [GO:0045926]; negative regulation of imaginal disc growth [GO:0045571]; negative regulation of organ growth [GO:0046621]; positive regulation of apoptotic process [GO:0043065]; positive regulation of hippo signaling [GO:0035332]; protein localization involved in establishment of planar polarity [GO:0090251]; pupal development [GO:0035209]; regulation of establishment of planar polarity [GO:0090175]; regulation of growth [GO:0040008]; regulation of imaginal disc growth [GO:0045570]; regulation of protein localization [GO:0032880]; regulation of tube length, open tracheal system [GO:0035159]; tissue development [GO:0009888]; wing disc development [GO:0035220] GO:0001736; GO:0001737; GO:0005509; GO:0005739; GO:0005886; GO:0007156; GO:0007157; GO:0007164; GO:0007446; GO:0007447; GO:0007476; GO:0008285; GO:0009888; GO:0010629; GO:0016324; GO:0016327; GO:0016336; GO:0016339; GO:0032880; GO:0035159; GO:0035209; GO:0035220; GO:0035332; GO:0040008; GO:0042067; GO:0043065; GO:0044331; GO:0045296; GO:0045317; GO:0045570; GO:0045571; GO:0045926; GO:0046621; GO:0048105; GO:0090175; GO:0090176; GO:0090251; GO:0098609 47247 XM_044309683.1 3 7 5 1 31 Q80XJ3 6.86e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 47248 XM_029323674.2 189 234 222 249 323 Q2KJ97 2.9e-85 Neurochondrin Bos taurus (Bovine) bone resorption [GO:0045453]; neuron projection development [GO:0031175]; regulation of neuronal synaptic plasticity [GO:0048168] GO:0005829; GO:0010008; GO:0030425; GO:0031175; GO:0043025; GO:0045453; GO:0048168; GO:0098794 47249 XR_006393488.1 117 30 85 33 176 NA NA NA NA NA NA 47250 XM_029344803.2 966 1205 364 758 686 Q15119 7.13e-131 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 2) (PDH kinase 2) (PDKII) Homo sapiens (Human) cellular response to nutrient [GO:0031670]; cellular response to reactive oxygen species [GO:0034614]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; insulin receptor signaling pathway [GO:0008286]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; protein phosphorylation [GO:0006468]; regulation of acetyl-CoA biosynthetic process from pyruvate [GO:0010510]; regulation of calcium-mediated signaling [GO:0050848]; regulation of cellular ketone metabolic process [GO:0010565]; regulation of gluconeogenesis [GO:0006111]; regulation of glucose metabolic process [GO:0010906]; regulation of pH [GO:0006885] GO:0004672; GO:0004740; GO:0005524; GO:0005654; GO:0005739; GO:0005759; GO:0005829; GO:0005967; GO:0006006; GO:0006111; GO:0006468; GO:0006885; GO:0008286; GO:0010510; GO:0010565; GO:0010906; GO:0031670; GO:0034614; GO:0042593; GO:0042803; GO:0050848; GO:0072332 47251 XM_044321742.1 0 0 0 0 54 NA NA NA NA NA NA 47252 XR_006392937.1 41 2 25 5 151 NA NA NA NA NA NA 47253 XM_029329146.2 0 61 0 394 0 Q12802 5.2e-82 A-kinase anchor protein 13 (AKAP-13) (AKAP-Lbc) (Breast cancer nuclear receptor-binding auxiliary protein) (Guanine nucleotide exchange factor Lbc) (Human thyroid-anchoring protein 31) (Lymphoid blast crisis oncogene) (LBC oncogene) (Non-oncogenic Rho GTPase-specific GTP exchange factor) (Protein kinase A-anchoring protein 13) (PRKA13) (p47) Homo sapiens (Human) adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process [GO:0086023]; adrenergic receptor signaling pathway [GO:0071875]; bone development [GO:0060348]; cardiac muscle cell differentiation [GO:0055007]; cell growth involved in cardiac muscle cell development [GO:0061049]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; nuclear export [GO:0051168]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Rho protein signal transduction [GO:0035025]; regulation of Rho protein signal transduction [GO:0035023]; regulation of sarcomere organization [GO:0060297]; regulation of small GTPase mediated signal transduction [GO:0051056] GO:0005078; GO:0005085; GO:0005634; GO:0005829; GO:0005938; GO:0007186; GO:0007507; GO:0016020; GO:0031267; GO:0035023; GO:0035025; GO:0043123; GO:0043406; GO:0046872; GO:0048471; GO:0051018; GO:0051056; GO:0051168; GO:0055007; GO:0060090; GO:0060297; GO:0060348; GO:0061049; GO:0071875; GO:0086023 47254 XM_044322038.1 0 164 74 445 308 NA NA NA NA NA NA 47255 XM_029343002.2 962 462 255 626 812 NA NA NA NA NA NA 47256 XM_029356068.2 1327 984 906 1216 969 B8V7S0 1.79e-66 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 47257 XM_044324396.1 0 484 0 274 0 Q9UPV0 2.68e-35 Centrosomal protein of 164 kDa (Cep164) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; cilium assembly [GO:0060271]; DNA repair [GO:0006281] GO:0005615; GO:0005654; GO:0005813; GO:0005814; GO:0005829; GO:0006281; GO:0007049; GO:0051301; GO:0060271; GO:0097539 47258 XM_044315158.1 33 94 13 173 64 NA NA NA NA NA NA 47259 XM_044323633.1 0 0 7 43 0 Q99315 8.08e-71 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 47260 XM_029348081.2 0 336 0 339 4 Q66H39 0 ATP-binding cassette sub-family F member 3 Rattus norvegicus (Rat) defense response to virus [GO:0051607] GO:0005524; GO:0016887; GO:0051607 47261 XM_029337513.2 63 22 11 13 39 NA NA NA NA NA NA 47262 XM_044316571.1 98 71 194 98 144 NA NA NA NA NA NA 47263 XM_044316945.1 36 46 82 101 89 NA NA NA NA NA NA 47264 XM_029334628.2 456 188 152 473 326 NA NA NA NA NA NA 47265 XM_044326362.1 1 30 15 4 4 NA NA NA NA NA NA 47266 XM_029324380.2 252 7 59 8 192 NA NA NA NA NA NA 47267 XM_029333873.2 2006 1456 997 2170 1945 Q8IV36 0 Protein HID1 (Down-regulated in multiple cancers 1) (HID1 domain-containing protein) (Protein hid-1 homolog) Homo sapiens (Human) NA GO:0000138; GO:0005737; GO:0005794; GO:0005797; GO:0005829; GO:0005881; GO:0016020; GO:0070062; GO:0090498 47268 XM_029346512.2 858 663 547 1025 689 P70473 2.82e-149 Alpha-methylacyl-CoA racemase (EC 5.1.99.4) (2-arylpropionyl-CoA epimerase) (2-methylacyl-CoA racemase) Rattus norvegicus (Rat) bile acid biosynthetic process [GO:0006699]; bile acid metabolic process [GO:0008206]; fatty acid metabolic process [GO:0006631] GO:0005737; GO:0005739; GO:0005777; GO:0006631; GO:0006699; GO:0008111; GO:0008206 47269 XM_044324427.1 19 31 8 36 61 NA NA NA NA NA NA 47270 XM_029336563.2 0 0 31 3 18 Q29496 3.16e-97 Cytochrome P450 3A24 (EC 1.14.14.1) (CYPIIIA24) Ovis aries (Sheep) NA GO:0004497; GO:0005506; GO:0005789; GO:0020037; GO:0070330 47271 XM_029324237.2 2 494 76 4 15 NA NA NA NA NA NA 47272 XM_044312148.1 0 2 11 0 13 NA NA NA NA NA NA 47273 XM_029353915.2 616 237 276 128 250 Q62962 5.71e-56 Acid-sensing ion channel 2 (ASIC2) (Amiloride-sensitive brain sodium channel) (Amiloride-sensitive brain sodium channel 2) (Amiloride-sensitive cation channel 1, neuronal) (Amiloride-sensitive cation channel neuronal 1) (Brain sodium channel 1) (BNC1) (BNaC1) (Mammalian degenerin homolog) (MDEG) Rattus norvegicus (Rat) cation transmembrane transport [GO:0098655]; cation transport [GO:0006812]; cellular response to acidic pH [GO:0071468]; cellular response to xenobiotic stimulus [GO:0071466]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; establishment of localization in cell [GO:0051649]; ion transmembrane transport [GO:0034220]; negative regulation of apoptotic process [GO:0043066]; phototransduction [GO:0007602]; positive regulation of cation channel activity [GO:2001259]; positive regulation of synapse assembly [GO:0051965]; protein localization to synapse [GO:0035418]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback [GO:0003026]; regulation of vasoconstriction [GO:0019229]; response to acidic pH [GO:0010447]; response to mechanical stimulus [GO:0009612]; sensory perception of sound [GO:0007605]; sensory perception of sour taste [GO:0050915]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814]; synapse assembly [GO:0007416] GO:0003026; GO:0005216; GO:0005248; GO:0005261; GO:0005886; GO:0006812; GO:0006814; GO:0007416; GO:0007602; GO:0007605; GO:0009612; GO:0010447; GO:0015280; GO:0016020; GO:0019229; GO:0022839; GO:0034220; GO:0034765; GO:0035418; GO:0035725; GO:0042391; GO:0043005; GO:0043025; GO:0043066; GO:0043197; GO:0045202; GO:0050915; GO:0050974; GO:0051649; GO:0051965; GO:0071466; GO:0071468; GO:0098655; GO:2001259 47274 XM_029347004.2 903 924 633 1021 659 NA NA NA NA NA NA 47275 XM_044312063.1 13 16 0 23 0 NA NA NA NA NA NA 47276 XM_044321822.1 6 3 6 0 23 NA NA NA NA NA NA 47277 XM_029330451.2 7 3 9 10 109 NA NA NA NA NA NA 47278 XM_029355940.2 1 0 0 5 34 NA NA NA NA NA NA 47279 XM_029335416.2 0 0 0 0 7 F4NUJ6 4.89e-125 tRNA (guanine(37)-N1)-methyltransferase (EC 2.1.1.228) (M1G-methyltransferase) (tRNA [GM37] methyltransferase) (tRNA methyltransferase 5) Batrachochytrium dendrobatidis (strain JAM81 / FGSC 10211) (Frog chytrid fungus) mitochondrial tRNA methylation [GO:0070901]; tRNA methylation [GO:0030488]; tRNA N1-guanine methylation [GO:0002939] GO:0002939; GO:0005634; GO:0005737; GO:0005759; GO:0008175; GO:0009019; GO:0030488; GO:0052906; GO:0070901 47280 XM_029340270.2 0 0 0 22 9 Q5RA50 3.64e-26 Protein FAM124A Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA NA 47281 XM_044324168.1 722 864 749 896 436 NA NA NA NA NA NA 47282 XR_006394843.1 499 511 306 437 348 NA NA NA NA NA NA 47283 XM_029326448.2 0 7 0 1 6 NA NA NA NA NA NA 47284 XM_029333437.2 0 13 341 9 1261 P55115 9.2e-48 Zinc metalloproteinase nas-15 (EC 3.4.24.-) (Nematode astacin 15) Caenorhabditis elegans proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0006508; GO:0008270 47285 XR_006397522.1 101 88 148 89 112 NA NA NA NA NA NA 47286 XM_029344369.2 6 10 26 29 113 P26794 1.42e-55 Serine/threonine-protein kinase pim-1 (EC 2.7.11.1) Rattus norvegicus (Rat) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cellular detoxification [GO:1990748]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cardioblast proliferation [GO:1905062]; positive regulation of DNA-templated transcription [GO:0045893]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of transmembrane transporter activity [GO:0022898]; vitamin D receptor signaling pathway [GO:0070561] GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0005886; GO:0006468; GO:0006915; GO:0007049; GO:0022898; GO:0030145; GO:0043024; GO:0043066; GO:0043433; GO:0045893; GO:0046777; GO:0050821; GO:0060045; GO:0070561; GO:0090336; GO:0106310; GO:1902033; GO:1905062; GO:1990748 47287 XM_029335470.2 445 877 195 161 402 NA NA NA NA NA NA 47288 XM_044320756.1 88 0 82 29 0 NA NA NA NA NA NA 47289 XM_044327473.1 95 90 30 229 75 Q5DU56 1.9e-82 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 47290 XM_044327473.1 95 90 30 229 75 Q5DU56 6.14e-57 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 47291 XM_044327473.1 95 90 30 229 75 Q5DU56 1.32e-22 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 47292 XM_029330526.2 434 233 211 398 365 NA NA NA NA NA NA 47293 XM_044317967.1 0 0 0 464 0 NA NA NA NA NA NA 47294 XM_029337289.2 286 142 205 127 206 Q5R7A2 4.35e-152 Chitobiosyldiphosphodolichol beta-mannosyltransferase (EC 2.4.1.142) (Asparagine-linked glycosylation protein 1 homolog) (Beta-1,4-mannosyltransferase) (GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase) (GDP-mannose-dolichol diphosphochitobiose mannosyltransferase) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) dolichol-linked oligosaccharide biosynthetic process [GO:0006488] GO:0004578; GO:0005789; GO:0006488 47295 XM_029355860.2 378 271 184 361 335 Q08DJ7 6.22e-113 Protein AAR2 homolog (AAR2 splicing factor homolog) Bos taurus (Bovine) spliceosomal tri-snRNP complex assembly [GO:0000244] GO:0000244; GO:0005681 47296 XM_044306817.1 408 128 0 597 531 P98070 7.19e-21 Bone morphogenetic protein 1 (BMP-1) (EC 3.4.24.-) Xenopus laevis (African clawed frog) cartilage development [GO:0051216]; cell differentiation [GO:0030154]; ossification [GO:0001503]; proteolysis [GO:0006508] GO:0001503; GO:0004222; GO:0005125; GO:0005509; GO:0005615; GO:0005794; GO:0006508; GO:0008083; GO:0008270; GO:0030154; GO:0051216 47297 XR_006392361.1 76 0 29 18 36 NA NA NA NA NA NA 47298 XM_044307581.1 0 14 11 0 0 P0CT39 7.55e-79 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 47299 XM_029348645.2 0 0 0 0 84 NA NA NA NA NA NA 47300 XM_029345497.2 3804 3455 2174 4982 4440 P54357 1.17e-54 Myosin-2 essential light chain (Myosin II essential light chain) (Non-muscle myosin essential light chain) Drosophila melanogaster (Fruit fly) actin filament-based movement [GO:0030048] GO:0005509; GO:0005829; GO:0016460; GO:0017022; GO:0030048; GO:0031475; GO:0031476; GO:0031477; GO:0032036 47301 XM_044315970.1 0 6 0 5 7 NA NA NA NA NA NA 47302 XM_029344106.2 316 270 151 208 278 Q5U3S7 3.21e-108 Nitric oxide synthase-interacting protein (E3 ubiquitin-protein ligase NOSIP) (EC 2.3.2.27) (RING-type E3 ubiquitin transferase NOSIP) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005634; GO:0005737; GO:0061630 47303 XM_029347833.2 621 705 434 598 527 Q3T000 7.52e-79 Synaptobrevin homolog YKT6 (EC 2.3.1.-) Bos taurus (Bovine) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147]; vesicle docking involved in exocytosis [GO:0006904]; vesicle targeting [GO:0006903] GO:0000139; GO:0005484; GO:0005739; GO:0005768; GO:0005783; GO:0005794; GO:0005829; GO:0005886; GO:0006888; GO:0006903; GO:0006904; GO:0015031; GO:0019706; GO:0030659; GO:0042147 47304 XR_006393067.1 41 2 25 5 151 NA NA NA NA NA NA 47305 XM_044307163.1 42 2 7 41 12 NA NA NA NA NA NA 47306 XR_003824916.2 4542 5400 2888 3940 1914 NA NA NA NA NA NA 47307 XM_044316082.1 53 0 75 39 77 NA NA NA NA NA NA 47308 XM_029338464.2 150 209 70 127 100 Q84JE8 2.51e-47 Polynucleotide 3'-phosphatase ZDP (EC 3.1.3.32) (DNA nick sensor protein) Arabidopsis thaliana (Mouse-ear cress) DNA demethylation [GO:0080111]; DNA repair [GO:0006281]; nucleotide phosphorylation [GO:0046939] GO:0003690; GO:0005654; GO:0006281; GO:0008270; GO:0046403; GO:0046404; GO:0046939; GO:0080111 47309 XM_044322240.1 158 14 51 5 296 NA NA NA NA NA NA 47310 XM_029337313.2 0 0 3 0 17 F1R8P4 3.37e-51 Glycine receptor subunit alpha-2 Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0004888; GO:0005254; GO:0016594; GO:0016933; GO:0022824; GO:0034707; GO:0042995; GO:0045211; GO:0046872 47311 XM_044317840.1 9 2 22 0 38 NA NA NA NA NA NA 47312 XM_044307836.1 157 107 256 109 248 NA NA NA NA NA NA 47313 XM_044323343.1 291 348 69 264 496 P55011 0 Solute carrier family 12 member 2 (Basolateral Na-K-Cl symporter) (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2) Homo sapiens (Human) aging [GO:0007568]; ammonium transmembrane transport [GO:0072488]; cell volume homeostasis [GO:0006884]; cellular chloride ion homeostasis [GO:0030644]; cellular potassium ion homeostasis [GO:0030007]; cellular response to chemokine [GO:1990869]; cellular response to potassium ion [GO:0035865]; cellular sodium ion homeostasis [GO:0006883]; chloride ion homeostasis [GO:0055064]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid signaling pathway [GO:0007214]; hyperosmotic response [GO:0006972]; inorganic anion import across plasma membrane [GO:0098658]; inorganic cation import across plasma membrane [GO:0098659]; ion transport [GO:0006811]; maintenance of blood-brain barrier [GO:0035633]; negative regulation of vascular wound healing [GO:0061044]; positive regulation of aspartate secretion [GO:1904450]; positive regulation of cell volume [GO:0045795]; potassium ion homeostasis [GO:0055075]; potassium ion import across plasma membrane [GO:1990573]; regulation of matrix metallopeptidase secretion [GO:1904464]; regulation of spontaneous synaptic transmission [GO:0150003]; sodium ion homeostasis [GO:0055078]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725]; T cell chemotaxis [GO:0010818]; transepithelial ammonium transport [GO:0070634]; transepithelial chloride transport [GO:0030321]; transport across blood-brain barrier [GO:0150104] GO:0005829; GO:0005886; GO:0006811; GO:0006883; GO:0006884; GO:0006972; GO:0007214; GO:0007568; GO:0008511; GO:0008519; GO:0009925; GO:0010818; GO:0015079; GO:0015377; GO:0015379; GO:0016020; GO:0016323; GO:0016324; GO:0016328; GO:0019901; GO:0030007; GO:0030321; GO:0030644; GO:0030659; GO:0031253; GO:0035633; GO:0035725; GO:0035865; GO:0042995; GO:0043005; GO:0043025; GO:0044297; GO:0044298; GO:0045795; GO:0046873; GO:0051087; GO:0051879; GO:0055064; GO:0055075; GO:0055078; GO:0061044; GO:0070062; GO:0070634; GO:0071944; GO:0072488; GO:0098658; GO:0098659; GO:0098719; GO:0150003; GO:0150104; GO:1902476; GO:1903561; GO:1904450; GO:1904464; GO:1990573; GO:1990869 47314 XM_029337374.2 1436 1037 613 1198 1520 Q63ZP7 8.2e-87 DDB1- and CUL4-associated factor 12-A (WD repeat-containing protein 40A-A) Xenopus laevis (African clawed frog) protein ubiquitination [GO:0016567]; regulation of autophagy [GO:0010506]; ubiquitin-dependent protein catabolic process via the C-end degron rule pathway [GO:0140627] GO:0005737; GO:0005815; GO:0010506; GO:0016567; GO:0080008; GO:0140627; GO:1990756 47315 XR_006396846.1 120 209 115 206 466 NA NA NA NA NA NA 47316 XM_044311191.1 46 0 0 0 0 NA NA NA NA NA NA 47317 XM_044317662.1 728 462 678 912 1304 Q0VG85 1.04e-142 Coiled-coil domain-containing protein 162 Mus musculus (Mouse) NA NA 47318 XM_029341146.2 250 0 55 6 37 NA NA NA NA NA NA 47319 XM_044324688.1 26 16 30 27 42 NA NA NA NA NA NA 47320 XR_003825655.2 1597 882 225 412 487 NA NA NA NA NA NA 47321 XM_044322568.1 581 391 475 0 206 P49916 0 DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3) Homo sapiens (Human) base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cell cycle [GO:0007049]; cell division [GO:0051301]; DNA biosynthetic process [GO:0071897]; DNA ligation [GO:0006266]; double-strand break repair [GO:0006302]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; double-strand break repair via homologous recombination [GO:0000724]; lagging strand elongation [GO:0006273]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of mitochondrial DNA replication [GO:0090298] GO:0000724; GO:0003677; GO:0003909; GO:0003910; GO:0005524; GO:0005634; GO:0005654; GO:0005739; GO:0006266; GO:0006273; GO:0006287; GO:0006288; GO:0006302; GO:0007005; GO:0007049; GO:0008270; GO:0043504; GO:0051301; GO:0070421; GO:0071897; GO:0090298; GO:0097681 47322 XM_029343982.2 108 237 135 127 303 NA NA NA NA NA NA 47323 XM_029346873.2 83 468 40 220 328 NA NA NA NA NA NA 47324 XM_044307941.1 165 113 49 0 120 NA NA NA NA NA NA 47325 XM_029353274.2 145 47 138 249 185 A4IIM3 2.46e-113 Target of rapamycin complex 2 subunit MAPKAP1 (TORC2 subunit MAPKAP1) (Mitogen-activated protein kinase 2-associated protein 1) (Stress-activated map kinase-interacting protein 1) (SAPK-interacting protein 1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0031932 47326 XM_029329021.2 0 10 8 10 7 Q8BLA8 4.48e-27 Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Wasabi receptor) Mus musculus (Mouse) calcium ion transmembrane import into cytosol [GO:0097553]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cell surface receptor signaling pathway [GO:0007166]; cellular calcium ion homeostasis [GO:0006874]; cellular response to carbon dioxide [GO:0071244]; cellular response to cold [GO:0070417]; cellular response to heat [GO:0034605]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to organic substance [GO:0071310]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; positive regulation of anion transport [GO:1903793]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of sensory perception of pain [GO:1904058]; protein homotetramerization [GO:0051289]; regulation of blood circulation [GO:1903522]; regulation of neuronal action potential [GO:0098908]; response to cold [GO:0009409]; response to hydrogen peroxide [GO:0042542]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; sensory perception of pain [GO:0019233]; thermoception [GO:0050955]; urinary bladder smooth muscle contraction [GO:0014832] GO:0005216; GO:0005245; GO:0005262; GO:0005886; GO:0006816; GO:0006874; GO:0007166; GO:0009409; GO:0009410; GO:0010033; GO:0014070; GO:0014832; GO:0015267; GO:0015278; GO:0016020; GO:0016324; GO:0019233; GO:0030424; GO:0032421; GO:0034605; GO:0035774; GO:0042542; GO:0042802; GO:0048265; GO:0050955; GO:0050966; GO:0050968; GO:0050974; GO:0051289; GO:0070301; GO:0070417; GO:0070588; GO:0071244; GO:0071310; GO:0097553; GO:0097604; GO:0098908; GO:1903522; GO:1903793; GO:1904058; GO:1990760 47327 XM_029328648.2 107 83 100 159 156 Q0VD42 6.45e-57 TLC domain-containing protein 5 (Transmembrane protein 136) Bos taurus (Bovine) NA GO:0016020 47328 XM_044310683.1 9 0 0 0 3 NA NA NA NA NA NA 47329 XM_044328121.1 41 19 21 22 100 NA NA NA NA NA NA 47330 XM_044321095.1 299 165 188 327 450 E9Q6P5 0 Tetratricopeptide repeat protein 7B (TPR repeat protein 7B) Mus musculus (Mouse) phosphatidylinositol phosphate biosynthetic process [GO:0046854]; protein localization to plasma membrane [GO:0072659] GO:0005829; GO:0005886; GO:0046854; GO:0072659 47331 XR_006393968.1 41 27 37 16 40 NA NA NA NA NA NA 47332 XR_003822851.2 0 0 2 0 13 Q15269 0 Periodic tryptophan protein 2 homolog Homo sapiens (Human) maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; ribosomal small subunit assembly [GO:0000028] GO:0000028; GO:0000462; GO:0003723; GO:0005654; GO:0032040; GO:0034388 47333 XM_029328697.2 93 10 9 7 55 NA NA NA NA NA NA 47334 XM_044315795.1 0 0 0 15 17 NA NA NA NA NA NA 47335 XM_029332887.2 1878 822 386 1529 503 NA NA NA NA NA NA 47336 XM_044325697.1 890 532 419 532 1570 NA NA NA NA NA NA 47337 XM_029336782.2 3584 2132 2101 3436 2943 NA NA NA NA NA NA 47338 XM_029331915.2 53 0 0 0 104 Q8TC84 3.15e-95 Fibronectin type 3 and ankyrin repeat domains protein 1 Homo sapiens (Human) negative regulation of apoptotic process [GO:0043066]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of apoptotic process [GO:0042981] GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005929; GO:0036064; GO:0042981; GO:0043065; GO:0043066; GO:0045893; GO:0051091; GO:0097546 47339 XM_044327620.1 0 9 0 0 0 P84039 1.5e-60 Ectonucleotide pyrophosphatase/phosphodiesterase family member 5 (E-NPP 5) (NPP-5) (EC 3.1.-.-) Rattus norvegicus (Rat) cell communication [GO:0007154] GO:0000210; GO:0005886; GO:0007154; GO:0008270; GO:0016020 47340 XM_029357348.2 568 1751 639 1566 2783 Q6IRI9 4.56e-167 Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.-) (Dimethylaniline oxidase 2) (Pulmonary flavin-containing monooxygenase 2) (FMO 2) Rattus norvegicus (Rat) energy homeostasis [GO:0097009]; NADP metabolic process [GO:0006739]; NADPH oxidation [GO:0070995]; negative regulation of fatty acid oxidation [GO:0046322]; organic acid metabolic process [GO:0006082]; oxygen metabolic process [GO:0072592]; toxin metabolic process [GO:0009404]; xenobiotic metabolic process [GO:0006805] GO:0004497; GO:0004499; GO:0005789; GO:0006082; GO:0006739; GO:0006805; GO:0009404; GO:0016020; GO:0046322; GO:0047822; GO:0050660; GO:0050661; GO:0070995; GO:0072592; GO:0097009 47341 XM_044314501.1 46 0 5 105 32 NA NA NA NA NA NA 47342 XM_044313808.1 0 10 3 7 21 P0DP43 3.98e-28 Cation channel sperm-associated auxiliary subunit epsilon (CatSper-epsilon) (CatSperepsilon) (C1orf101-like protein) Mus musculus (Mouse) flagellated sperm motility [GO:0030317]; sperm capacitation [GO:0048240] GO:0030317; GO:0036128; GO:0048240; GO:0097228 47343 XM_029323759.2 0 0 0 0 29 NA NA NA NA NA NA 47344 XM_029330030.2 18 42 0 66 0 O18276 6.2e-59 Gamma-aminobutyric acid receptor subunit beta (GABA(A) receptor subunit beta) Caenorhabditis elegans chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165] GO:0004890; GO:0005230; GO:0005231; GO:0005254; GO:0005886; GO:0006811; GO:0007165; GO:0007268; GO:0030594; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:1902476; GO:1902711; GO:1904315 47345 XM_044323238.1 154 17 13 166 124 Q8VCH8 2.74e-74 UBX domain-containing protein 4 (Erasin) (UBX domain-containing protein 2) Mus musculus (Mouse) response to unfolded protein [GO:0006986]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0005635; GO:0005783; GO:0005789; GO:0005829; GO:0006986; GO:0030433 47346 XM_044327573.1 444 361 217 558 585 Q8NEV4 0 Myosin-IIIa (EC 2.7.11.1) Homo sapiens (Human) cochlea morphogenesis [GO:0090103]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of filopodium assembly [GO:0051491]; protein autophosphorylation [GO:0046777]; regulation of actin filament length [GO:0030832]; response to stimulus [GO:0050896]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] GO:0000146; GO:0001917; GO:0003779; GO:0004672; GO:0004674; GO:0005516; GO:0005524; GO:0005737; GO:0007601; GO:0007605; GO:0016459; GO:0018105; GO:0030175; GO:0030832; GO:0031941; GO:0032426; GO:0032433; GO:0043531; GO:0046777; GO:0050896; GO:0051491; GO:0060002; GO:0090103; GO:0106310 47347 XM_044327695.1 157 27 172 0 181 NA NA NA NA NA NA 47348 XM_044315614.1 339 230 229 379 344 Q9QZU7 1.11e-85 Gamma-butyrobetaine dioxygenase (EC 1.14.11.1) (Gamma-butyrobetaine hydroxylase) (Gamma-BBH) (Gamma-butyrobetaine,2-oxoglutarate dioxygenase) Rattus norvegicus (Rat) carnitine biosynthetic process [GO:0045329] GO:0005506; GO:0005739; GO:0008270; GO:0008336; GO:0042802; GO:0045329 47349 XM_044316293.1 6 0 4 0 0 NA NA NA NA NA NA 47350 XM_029348367.2 5 0 16 46 27 NA NA NA NA NA NA 47351 XM_029326813.2 9 0 1 12 1 NA NA NA NA NA NA 47352 XM_029330882.2 138 70 126 238 200 NA NA NA NA NA NA 47353 XM_044312363.1 12 1 1 0 8 NA NA NA NA NA NA 47354 XM_044314112.1 7 6 3 0 14 NA NA NA NA NA NA 47355 XM_029348872.2 13 46 40 64 19 Q9W2Q5 1.03e-64 NA NA NA NA 47356 XR_006396381.1 203 49 19 31 221 NA NA NA NA NA NA 47357 XM_044309108.1 0 16 0 59 44 NA NA NA NA NA NA 47358 XM_029324300.2 0 1 0 0 17 Q9UBM8 1.22e-62 Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C (EC 2.4.1.145) (N-acetylglucosaminyltransferase IV homolog) (hGnT-IV-H) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVc) (GlcNAc-T IVc) (GnT-IVc) (N-acetylglucosaminyltransferase IVc) (UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVc) Homo sapiens (Human) protein N-linked glycosylation [GO:0006487]; viral protein processing [GO:0019082] GO:0000139; GO:0006487; GO:0008375; GO:0008454; GO:0019082; GO:0046872 47359 XM_029333674.2 115 75 74 67 41 NA NA NA NA NA NA 47360 XM_029345695.2 72 68 86 73 92 F1NZI4 9.14e-147 Protein-glucosylgalactosylhydroxylysine glucosidase (EC 3.2.1.107) (Acid trehalase-like protein 1) Gallus gallus (Chicken) carbohydrate metabolic process [GO:0005975] GO:0004553; GO:0005829; GO:0005975; GO:0047402 47361 XM_029333414.2 183 59 57 188 198 Q6PEM8 3.04e-36 Proton-coupled folate transporter (Heme carrier protein 1) (PCFT/HCP1) (Solute carrier family 46 member 1) Mus musculus (Mouse) folate import across plasma membrane [GO:1904447]; folate transmembrane transport [GO:0098838]; folic acid transport [GO:0015884]; heme transport [GO:0015886]; proton transmembrane transport [GO:1902600]; transmembrane transport [GO:0055085] GO:0005542; GO:0005737; GO:0005768; GO:0005886; GO:0008517; GO:0010008; GO:0015078; GO:0015232; GO:0015293; GO:0015350; GO:0015884; GO:0015886; GO:0016020; GO:0016323; GO:0016324; GO:0022857; GO:0031526; GO:0055085; GO:0098838; GO:0140211; GO:1902600; GO:1904447 47362 XM_029329824.2 222 63 170 76 278 NA NA NA NA NA NA 47363 XR_006396591.1 23 96 57 55 95 NA NA NA NA NA NA 47364 XM_044311653.1 440 371 80 266 195 B8VIU6 3.16e-73 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 47365 XM_044317931.1 675 335 504 618 1014 Q29M42 2.78e-104 Coiled-coil and C2 domain-containing protein 1-like Drosophila pseudoobscura pseudoobscura (Fruit fly) NA GO:0001227 47366 XM_044324562.1 0 2 0 1 129 NA NA NA NA NA NA 47367 XM_029340290.2 20 8 14 17 7 P61752 4.15e-21 Histamine H2 receptor (H2R) (HH2R) (Gastric receptor I) Pongo pygmaeus (Bornean orangutan) gastric acid secretion [GO:0001696]; positive regulation of vasoconstriction [GO:0045907] GO:0001696; GO:0004969; GO:0005886; GO:0045907 47368 XM_044311518.1 29 153 3 56 99 NA NA NA NA NA NA 47369 XM_029327984.2 0 0 3 7 3 NA NA NA NA NA NA 47370 XM_044314777.1 91 0 48 0 123 NA NA NA NA NA NA 47371 XM_029349753.2 2223 1539 1201 2461 1781 Q80TP3 0 E3 ubiquitin-protein ligase UBR5 (EC 2.3.2.26) (E3 ubiquitin-protein ligase, HECT domain-containing 1) (HECT-type E3 ubiquitin transferase UBR5) (Hyperplastic discs protein homolog) Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA repair-dependent chromatin remodeling [GO:0140861]; negative regulation of double-strand break repair [GO:2000780]; negative regulation of histone H2A K63-linked ubiquitination [GO:1901315]; negative regulation of interleukin-17 production [GO:0032700]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of protein import into nucleus [GO:0042307]; progesterone receptor signaling pathway [GO:0050847]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of double-strand break repair [GO:2000779]; regulation of protein stability [GO:0031647] GO:0000209; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006281; GO:0006974; GO:0008270; GO:0010628; GO:0016567; GO:0019904; GO:0031647; GO:0032700; GO:0032991; GO:0034450; GO:0042307; GO:0043130; GO:0048471; GO:0050847; GO:0061630; GO:0070936; GO:0090263; GO:0140861; GO:1901315; GO:2000779; GO:2000780 47372 XM_029349753.2 2223 1539 1201 2461 1781 Q80TP3 1.84e-174 E3 ubiquitin-protein ligase UBR5 (EC 2.3.2.26) (E3 ubiquitin-protein ligase, HECT domain-containing 1) (HECT-type E3 ubiquitin transferase UBR5) (Hyperplastic discs protein homolog) Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA repair-dependent chromatin remodeling [GO:0140861]; negative regulation of double-strand break repair [GO:2000780]; negative regulation of histone H2A K63-linked ubiquitination [GO:1901315]; negative regulation of interleukin-17 production [GO:0032700]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of protein import into nucleus [GO:0042307]; progesterone receptor signaling pathway [GO:0050847]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of double-strand break repair [GO:2000779]; regulation of protein stability [GO:0031647] GO:0000209; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006281; GO:0006974; GO:0008270; GO:0010628; GO:0016567; GO:0019904; GO:0031647; GO:0032700; GO:0032991; GO:0034450; GO:0042307; GO:0043130; GO:0048471; GO:0050847; GO:0061630; GO:0070936; GO:0090263; GO:0140861; GO:1901315; GO:2000779; GO:2000780 47373 XM_029349753.2 2223 1539 1201 2461 1781 Q80TP3 1.03e-119 E3 ubiquitin-protein ligase UBR5 (EC 2.3.2.26) (E3 ubiquitin-protein ligase, HECT domain-containing 1) (HECT-type E3 ubiquitin transferase UBR5) (Hyperplastic discs protein homolog) Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA repair-dependent chromatin remodeling [GO:0140861]; negative regulation of double-strand break repair [GO:2000780]; negative regulation of histone H2A K63-linked ubiquitination [GO:1901315]; negative regulation of interleukin-17 production [GO:0032700]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of protein import into nucleus [GO:0042307]; progesterone receptor signaling pathway [GO:0050847]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of double-strand break repair [GO:2000779]; regulation of protein stability [GO:0031647] GO:0000209; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006281; GO:0006974; GO:0008270; GO:0010628; GO:0016567; GO:0019904; GO:0031647; GO:0032700; GO:0032991; GO:0034450; GO:0042307; GO:0043130; GO:0048471; GO:0050847; GO:0061630; GO:0070936; GO:0090263; GO:0140861; GO:1901315; GO:2000779; GO:2000780 47374 XM_029349753.2 2223 1539 1201 2461 1781 Q80TP3 2.97e-45 E3 ubiquitin-protein ligase UBR5 (EC 2.3.2.26) (E3 ubiquitin-protein ligase, HECT domain-containing 1) (HECT-type E3 ubiquitin transferase UBR5) (Hyperplastic discs protein homolog) Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA repair-dependent chromatin remodeling [GO:0140861]; negative regulation of double-strand break repair [GO:2000780]; negative regulation of histone H2A K63-linked ubiquitination [GO:1901315]; negative regulation of interleukin-17 production [GO:0032700]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of protein import into nucleus [GO:0042307]; progesterone receptor signaling pathway [GO:0050847]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of double-strand break repair [GO:2000779]; regulation of protein stability [GO:0031647] GO:0000209; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006281; GO:0006974; GO:0008270; GO:0010628; GO:0016567; GO:0019904; GO:0031647; GO:0032700; GO:0032991; GO:0034450; GO:0042307; GO:0043130; GO:0048471; GO:0050847; GO:0061630; GO:0070936; GO:0090263; GO:0140861; GO:1901315; GO:2000779; GO:2000780 47375 XM_044323564.1 161 58 102 170 132 P54132 4.83e-35 RecQ-like DNA helicase BLM (EC 3.6.4.12) (Bloom syndrome protein) (DNA helicase, RecQ-like type 2) (RecQ2) (RecQ protein-like 3) Homo sapiens (Human) cellular response to camptothecin [GO:0072757]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hydroxyurea [GO:0072711]; cellular response to ionizing radiation [GO:0071479]; DNA double-strand break processing [GO:0000729]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724]; G-quadruplex DNA unwinding [GO:0044806]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; negative regulation of cell division [GO:0051782]; negative regulation of DNA recombination [GO:0045910]; positive regulation of DNA-templated transcription [GO:0045893]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of DNA-templated DNA replication [GO:0090329]; replication fork processing [GO:0031297]; replication fork protection [GO:0048478]; resolution of recombination intermediates [GO:0071139]; response to X-ray [GO:0010165]; t-circle formation [GO:0090656]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; telomeric D-loop disassembly [GO:0061820] GO:0000079; GO:0000228; GO:0000400; GO:0000403; GO:0000405; GO:0000723; GO:0000724; GO:0000729; GO:0000800; GO:0002039; GO:0003677; GO:0003678; GO:0003697; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0005657; GO:0005694; GO:0005730; GO:0005737; GO:0005829; GO:0006260; GO:0006268; GO:0006281; GO:0006310; GO:0006974; GO:0007095; GO:0008094; GO:0008270; GO:0009378; GO:0010165; GO:0016363; GO:0016605; GO:0016887; GO:0031297; GO:0031422; GO:0032201; GO:0032508; GO:0032991; GO:0042802; GO:0042803; GO:0043138; GO:0044806; GO:0045893; GO:0045910; GO:0048478; GO:0051259; GO:0051260; GO:0051782; GO:0051880; GO:0061749; GO:0061820; GO:0061821; GO:0061849; GO:0071139; GO:0071479; GO:0072711; GO:0072757; GO:0090329; GO:0090656; GO:0140677; GO:1905773; GO:1990814 47376 XR_006393690.1 239 3 43 149 197 NA NA NA NA NA NA 47377 XM_044313591.1 20 28 23 6 192 NA NA NA NA NA NA 47378 XM_044315022.1 162 54 91 48 200 NA NA NA NA NA NA 47379 XM_044311835.1 719 384 0 408 171 Q9W352 4.37e-95 CXXC-type zinc finger protein 1 (PHD finger and CXXC domain-containing protein 1) Drosophila melanogaster (Fruit fly) histone H3-K4 methylation [GO:0051568]; positive regulation of DNA-templated transcription [GO:0045893] GO:0003677; GO:0008270; GO:0035064; GO:0045893; GO:0048188; GO:0051568 47380 XM_044329253.1 0 6 0 1 0 NA NA NA NA NA NA 47381 XM_044327926.1 141 262 57 111 55 NA NA NA NA NA NA 47382 XM_044318542.1 44 5 46 25 287 O75899 2.3e-90 Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51) (HG20) Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway [GO:0007186]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; neuron-glial cell signaling [GO:0150099]; synaptic transmission, GABAergic [GO:0051932] GO:0004888; GO:0004965; GO:0005737; GO:0005886; GO:0007186; GO:0007193; GO:0007194; GO:0007214; GO:0007268; GO:0038039; GO:0043005; GO:0045211; GO:0046982; GO:0051932; GO:0150099; GO:1902710; GO:1902712 47383 XM_029342644.2 105 157 95 42 186 NA NA NA NA NA NA 47384 XM_029336747.2 0 3 0 19 0 NA NA NA NA NA NA 47385 XR_003826544.2 377 317 157 522 468 NA NA NA NA NA NA 47386 XM_044307464.1 267 242 125 236 227 Q53G59 8.33e-36 Kelch-like protein 12 (CUL3-interacting protein 1) (DKIR homolog) (hDKIR) Homo sapiens (Human) COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; protein monoubiquitination [GO:0006513]; Wnt signaling pathway [GO:0016055] GO:0005829; GO:0006513; GO:0006888; GO:0014029; GO:0014032; GO:0016055; GO:0030127; GO:0030134; GO:0031463; GO:0034451; GO:0042802; GO:0043231; GO:0048208 47387 XM_044308186.1 88 0 7 0 0 Q9V9A7 1.2e-163 Probable methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCase subunit beta) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 2) (3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta) Drosophila melanogaster (Fruit fly) coenzyme A metabolic process [GO:0015936]; leucine catabolic process [GO:0006552]; regulation of eclosion [GO:0007563] GO:0004485; GO:0005524; GO:0005739; GO:0005759; GO:0006552; GO:0007563; GO:0015936; GO:1905202 47388 XM_044308123.1 3111 3470 2402 3313 1754 Q6P8Y1 3.63e-91 Calcyphosin-like protein Mus musculus (Mouse) NA GO:0005509; GO:0005737 47389 XM_029324037.2 171 7 0 78 223 Q99807 2.74e-55 5-demethoxyubiquinone hydroxylase, mitochondrial (DMQ hydroxylase) (EC 1.14.99.60) (Timing protein clk-1 homolog) (Ubiquinone biosynthesis monooxygenase COQ7) Homo sapiens (Human) determination of adult lifespan [GO:0008340]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression [GO:0010468]; regulation of reactive oxygen species metabolic process [GO:2000377]; ubiquinone biosynthetic process [GO:0006744] GO:0000122; GO:0003682; GO:0005634; GO:0005694; GO:0005739; GO:0005743; GO:0006744; GO:0008340; GO:0008682; GO:0010468; GO:0016709; GO:0031314; GO:0045944; GO:0046872; GO:0110142; GO:2000377 47390 XM_044324906.1 0 0 10 0 0 Q9UQ26 2.41e-63 Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2) (Rab-3-interacting protein 3) Homo sapiens (Human) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-ion regulated exocytosis [GO:0017156]; cell differentiation [GO:0030154]; insulin secretion [GO:0030073]; intracellular protein transport [GO:0006886]; positive regulation of dendrite extension [GO:1903861]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of synaptic transmission [GO:0050806]; regulation of exocytosis [GO:0017157]; regulation of membrane potential [GO:0042391]; regulation of synaptic plasticity [GO:0048167]; spontaneous neurotransmitter secretion [GO:0061669] GO:0006886; GO:0007188; GO:0017156; GO:0017157; GO:0030073; GO:0030154; GO:0031267; GO:0042391; GO:0042734; GO:0042995; GO:0044325; GO:0046872; GO:0048167; GO:0048786; GO:0048788; GO:0048791; GO:0050806; GO:0061669; GO:0070062; GO:0097151; GO:1903861; GO:2000463 47391 XM_044324906.1 0 0 10 0 0 Q9UQ26 1.41e-30 Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2) (Rab-3-interacting protein 3) Homo sapiens (Human) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-ion regulated exocytosis [GO:0017156]; cell differentiation [GO:0030154]; insulin secretion [GO:0030073]; intracellular protein transport [GO:0006886]; positive regulation of dendrite extension [GO:1903861]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of synaptic transmission [GO:0050806]; regulation of exocytosis [GO:0017157]; regulation of membrane potential [GO:0042391]; regulation of synaptic plasticity [GO:0048167]; spontaneous neurotransmitter secretion [GO:0061669] GO:0006886; GO:0007188; GO:0017156; GO:0017157; GO:0030073; GO:0030154; GO:0031267; GO:0042391; GO:0042734; GO:0042995; GO:0044325; GO:0046872; GO:0048167; GO:0048786; GO:0048788; GO:0048791; GO:0050806; GO:0061669; GO:0070062; GO:0097151; GO:1903861; GO:2000463 47392 XM_044312909.1 708 159 210 331 284 P69527 2.4e-122 Aminopeptidase O (AP-O) (EC 3.4.11.-) Rattus norvegicus (Rat) proteolysis [GO:0006508] GO:0005730; GO:0006508; GO:0008270; GO:0070006 47393 XM_029349405.2 0 0 0 71 121 NA NA NA NA NA NA 47394 XM_044327421.1 11 39 0 65 67 P50130 1.33e-37 D(1A) dopamine receptor (Dopamine D1 receptor) Sus scrofa (Pig) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; vasodilation [GO:0042311] GO:0004930; GO:0004952; GO:0005789; GO:0005886; GO:0007189; GO:0042311; GO:0043197 47395 XM_044315516.1 21 32 0 8 17 Q96AY4 1.02e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 47396 XM_029343886.2 361 206 200 164 297 Q925F4 6.25e-43 RING finger protein 37 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase RNF37) (U-box domain-containing protein 5) (UbcM4-interacting protein 5) Mus musculus (Mouse) protein polyubiquitination [GO:0000209] GO:0000209; GO:0005634; GO:0005654; GO:0005925; GO:0016604; GO:0031625; GO:0034450; GO:0046872; GO:0061630 47397 XM_029347244.2 119 0 142 19 31 Q86UA1 1.37e-177 Pre-mRNA-processing factor 39 (PRP39 homolog) Homo sapiens (Human) mRNA 5'-splice site recognition [GO:0000395] GO:0000243; GO:0000395; GO:0005685; GO:0071004 47398 XR_006395149.1 330 391 313 302 214 Q9NPC2 2.89e-35 Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3) (Two pore potassium channel KT3.2) (Two pore K(+) channel KT3.2) Homo sapiens (Human) potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; stabilization of membrane potential [GO:0030322] GO:0005267; GO:0005886; GO:0006813; GO:0008021; GO:0015271; GO:0022841; GO:0030322; GO:0071805; GO:1990573 47399 XM_044322608.1 1727 2549 853 1907 1225 A1A5V9 1.23e-27 Elongator complex protein 5 (Dermal papilla-derived protein 6 homolog) (Retinoic acid-induced protein 12) Danio rerio (Zebrafish) (Brachydanio rerio) positive regulation of cell migration [GO:0030335]; tRNA modification [GO:0006400]; tRNA wobble uridine modification [GO:0002098] GO:0002098; GO:0005634; GO:0005737; GO:0005829; GO:0006400; GO:0030335; GO:0033588 47400 XM_029324767.2 60 19 48 1177 532 NA NA NA NA NA NA 47401 XM_029323904.2 14 6 19 6 12 NA NA NA NA NA NA 47402 XM_029326450.2 104 105 133 47 45 NA NA NA NA NA NA 47403 XR_006394049.1 48 50 22 43 39 NA NA NA NA NA NA 47404 XR_006397773.1 9 9 12 16 14 NA NA NA NA NA NA 47405 XM_029348118.2 67 22 0 0 89 Q708S4 6.16e-55 Acid-sensing ion channel 4-A (ASIC4-A) (Acid-sensing ion channel 4.1) (Amiloride-sensitive cation channel 4-A) (ZASIC4.1) Danio rerio (Zebrafish) (Brachydanio rerio) sodium ion transmembrane transport [GO:0035725] GO:0005248; GO:0005261; GO:0005886; GO:0015280; GO:0035725; GO:0045177 47406 XM_044326819.1 1 4 5 3 8 Q09575 6.32e-22 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 47407 XM_029349082.2 84 79 84 108 82 NA NA NA NA NA NA 47408 XM_044314781.1 0 0 13 0 0 NA NA NA NA NA NA 47409 XM_044310850.1 52 1 56 35 0 Q99570 5.95e-39 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 47410 XM_044310850.1 52 1 56 35 0 Q99570 5.95e-39 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 47411 XM_044310850.1 52 1 56 35 0 Q99570 3.36e-23 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 47412 XM_044319821.1 24 15 7 33 49 NA NA NA NA NA NA 47413 XR_006393056.1 28 0 0 8 7 NA NA NA NA NA NA 47414 XM_044328309.1 398 226 222 295 403 P28339 0 DNA polymerase delta catalytic subunit (EC 2.7.7.7) (3'-5' exodeoxyribonuclease) (EC 3.1.11.-) Bos taurus (Bovine) base-excision repair, gap-filling [GO:0006287]; cellular response to UV [GO:0034644]; DNA biosynthetic process [GO:0071897]; DNA replication proofreading [GO:0045004]; DNA synthesis involved in DNA repair [GO:0000731]; DNA-templated DNA replication [GO:0006261]; error-free translesion synthesis [GO:0070987]; fatty acid homeostasis [GO:0055089]; nucleotide-excision repair, DNA gap filling [GO:0006297] GO:0000166; GO:0000731; GO:0003682; GO:0003684; GO:0003887; GO:0006261; GO:0006287; GO:0006297; GO:0008296; GO:0034644; GO:0043625; GO:0045004; GO:0046872; GO:0051539; GO:0055089; GO:0070987; GO:0071897 47415 XM_044311505.1 1312 46 70 857 72 NA NA NA NA NA NA 47416 XM_029338730.2 38018 82605 46618 50320 30967 P84175 2.7e-60 40S ribosomal protein S12 Gallus gallus (Chicken) positive regulation of canonical Wnt signaling pathway [GO:0090263]; translation [GO:0006412] GO:0003735; GO:0005794; GO:0006412; GO:0022627; GO:0090263 47417 XR_006392806.1 19 55 33 0 0 NA NA NA NA NA NA 47418 XM_044327420.1 603 490 466 273 346 P50130 6.56e-38 D(1A) dopamine receptor (Dopamine D1 receptor) Sus scrofa (Pig) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; vasodilation [GO:0042311] GO:0004930; GO:0004952; GO:0005789; GO:0005886; GO:0007189; GO:0042311; GO:0043197 47419 XM_044321355.1 162 0 0 0 0 Q96PY6 9.92e-146 Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase 1) (NimA-related protein kinase 1) (Renal carcinoma antigen NY-REN-55) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; cilium assembly [GO:0060271]; protein phosphorylation [GO:0006468] GO:0000242; GO:0004672; GO:0004674; GO:0004713; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0005829; GO:0006468; GO:0007049; GO:0016301; GO:0034451; GO:0046872; GO:0051301; GO:0060271; GO:0071889; GO:0106310 47420 XM_044318822.1 54 1 0 1 661 Q8IVV2 2.21e-84 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 47421 XM_044318822.1 54 1 0 1 661 Q8IVV2 1.28e-83 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 47422 XM_044318822.1 54 1 0 1 661 Q8IVV2 1.15e-80 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 47423 XM_044318822.1 54 1 0 1 661 Q8IVV2 1.64e-78 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 47424 XM_044318822.1 54 1 0 1 661 Q8IVV2 6.51e-65 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 47425 XM_044318822.1 54 1 0 1 661 Q8IVV2 8.65e-63 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 47426 XM_044318822.1 54 1 0 1 661 Q8IVV2 1.2e-61 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 47427 XM_044318822.1 54 1 0 1 661 Q8IVV2 2.69e-46 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 47428 XM_044322301.1 80 37 39 38 190 Q9GLP1 1.56e-29 Coagulation factor V (Activated protein C cofactor) [Cleaved into: Coagulation factor V heavy chain; Coagulation factor V light chain] Sus scrofa (Pig) blood circulation [GO:0008015]; blood coagulation [GO:0007596] GO:0005507; GO:0005576; GO:0007596; GO:0008015; GO:0031091 47429 XM_044322301.1 80 37 39 38 190 Q9GLP1 3.27e-24 Coagulation factor V (Activated protein C cofactor) [Cleaved into: Coagulation factor V heavy chain; Coagulation factor V light chain] Sus scrofa (Pig) blood circulation [GO:0008015]; blood coagulation [GO:0007596] GO:0005507; GO:0005576; GO:0007596; GO:0008015; GO:0031091 47430 XM_029334033.2 0 36 25 13 27 NA NA NA NA NA NA 47431 XM_044317474.1 2248 527 1660 2443 2168 Q60HG2 5.31e-84 Torsin-1A (Dystonia 1 protein) (Torsin ATPase 1) (EC 3.6.4.-) (Torsin family 1 member A) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) cell adhesion [GO:0007155]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated protein folding [GO:0061077]; ER-associated misfolded protein catabolic process [GO:0071712]; intermediate filament cytoskeleton organization [GO:0045104]; neuron projection development [GO:0031175]; nuclear envelope organization [GO:0006998]; nuclear membrane organization [GO:0071763]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; protein deneddylation [GO:0000338]; protein localization to nucleus [GO:0034504]; regulation of dopamine uptake involved in synaptic transmission [GO:0051584]; regulation of protein localization to cell surface [GO:2000008]; synaptic vesicle membrane organization [GO:0048499]; synaptic vesicle transport [GO:0048489]; wound healing, spreading of cells [GO:0044319] GO:0000338; GO:0005524; GO:0005635; GO:0005788; GO:0005856; GO:0006998; GO:0007155; GO:0008021; GO:0016887; GO:0030141; GO:0030426; GO:0030659; GO:0031175; GO:0031965; GO:0034504; GO:0042406; GO:0042802; GO:0044319; GO:0045104; GO:0048489; GO:0048499; GO:0051085; GO:0051584; GO:0061077; GO:0071712; GO:0071763; GO:0140662; GO:1900244; GO:2000008 47432 XM_029331721.2 6 56 0 50 0 Q8C1B2 2.43e-53 Protein mono-ADP-ribosyltransferase TIPARP (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 14) (ARTD14) (TCDD-inducible poly [ADP-ribose] polymerase) Mus musculus (Mouse) androgen metabolic process [GO:0008209]; cellular response to organic cyclic compound [GO:0071407]; estrogen metabolic process [GO:0008210]; face morphogenesis [GO:0060325]; female gonad development [GO:0008585]; hemopoiesis [GO:0030097]; kidney development [GO:0001822]; negative regulation of gene expression [GO:0010629]; nitrogen compound metabolic process [GO:0006807]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of protein catabolic process [GO:0045732]; post-embryonic development [GO:0009791]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; smooth muscle tissue development [GO:0048745]; vasculogenesis [GO:0001570] GO:0000987; GO:0001570; GO:0001822; GO:0003950; GO:0005634; GO:0006807; GO:0008209; GO:0008210; GO:0008585; GO:0009791; GO:0010629; GO:0016779; GO:0030097; GO:0045732; GO:0046872; GO:0048008; GO:0048705; GO:0048745; GO:0060021; GO:0060325; GO:0071407; GO:0140803; GO:1990404 47433 XR_006397718.1 29 22 1 4 57 Q7RTR2 2.92e-37 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 47434 XR_006397718.1 29 22 1 4 57 Q7RTR2 2.73e-27 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 47435 XR_006397718.1 29 22 1 4 57 Q7RTR2 7.84e-27 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 47436 XM_044311600.1 9 10 0 25 93 NA NA NA NA NA NA 47437 XR_006395652.1 3 9 2 20 10 NA NA NA NA NA NA 47438 XM_029357379.2 764 754 394 784 980 Q9VUL9 8.18e-39 Glycoprotein 3-alpha-L-fucosyltransferase A (EC 2.4.1.214) (Core alpha-(1,3)-fucosyltransferase) Drosophila melanogaster (Fruit fly) fucosylation [GO:0036065]; N-glycan fucosylation [GO:0036071]; nervous system development [GO:0007399]; protein glycosylation [GO:0006486] GO:0005797; GO:0006486; GO:0007399; GO:0008417; GO:0018392; GO:0032580; GO:0036065; GO:0036071; GO:0046920 47439 XM_044323016.1 1266 717 336 657 387 Q5XJ85 2.4e-28 Myeloid differentiation primary response protein MyD88 Danio rerio (Zebrafish) (Brachydanio rerio) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; monocyte activation [GO:0042117]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; neutrophil activation involved in immune response [GO:0002283]; neutrophil chemotaxis [GO:0030593]; positive regulation of hematopoietic progenitor cell differentiation [GO:1901534]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of hematopoietic progenitor cell differentiation [GO:1901532]; response to molecule of bacterial origin [GO:0002237]; Toll signaling pathway [GO:0008063] GO:0002218; GO:0002237; GO:0002283; GO:0002755; GO:0005737; GO:0005886; GO:0006954; GO:0008063; GO:0030593; GO:0035325; GO:0042117; GO:0042742; GO:0043123; GO:0045087; GO:0050830; GO:0070976; GO:1901532; GO:1901534 47440 XM_044319764.1 0 0 0 0 13 P0CT40 5.18e-88 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 47441 XM_029356335.2 25 9 10 3 7 NA NA NA NA NA NA 47442 XM_029343743.2 15 104 23 26 57 NA NA NA NA NA NA 47443 XM_044316020.1 80 118 77 180 198 A4IIK1 5.09e-53 Malignant fibrous histiocytoma-amplified sequence 1 homolog Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) inflammatory response [GO:0006954]; innate immune response [GO:0045087]; regulation of signal transduction [GO:0009966] GO:0005525; GO:0005737; GO:0006954; GO:0009966; GO:0045087 47444 XM_044328381.1 0 2 3 6 0 NA NA NA NA NA NA 47445 XR_006396167.1 31 8 40 41 81 NA NA NA NA NA NA 47446 XM_044316295.1 0 5 17 3 4 NA NA NA NA NA NA 47447 XM_044324292.1 37 0 64 0 0 Q9QYP0 0 Multiple epidermal growth factor-like domains protein 8 (Multiple EGF-like domains protein 8) (Epidermal growth factor-like protein 4) (EGF-like protein 4) Rattus norvegicus (Rat) animal organ morphogenesis [GO:0009887]; BMP signaling pathway [GO:0030509]; cell migration involved in gastrulation [GO:0042074]; coronary vasculature development [GO:0060976]; craniofacial suture morphogenesis [GO:0097094]; determination of digestive tract left/right asymmetry [GO:0071907]; determination of heart left/right asymmetry [GO:0061371]; determination of left/right symmetry [GO:0007368]; embryonic heart tube left/right pattern formation [GO:0060971]; embryonic heart tube morphogenesis [GO:0003143]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; epiboly involved in gastrulation with mouth forming second [GO:0055113]; fasciculation of sensory neuron axon [GO:0097155]; left/right pattern formation [GO:0060972]; limb morphogenesis [GO:0035108]; negative regulation of smoothened signaling pathway [GO:0045879]; positive regulation of axon extension involved in axon guidance [GO:0048842]; regulation of gene expression [GO:0010468]; tissue development [GO:0009888] GO:0003143; GO:0005509; GO:0005634; GO:0007368; GO:0009887; GO:0009888; GO:0010468; GO:0016020; GO:0030326; GO:0030509; GO:0035108; GO:0042074; GO:0045879; GO:0048704; GO:0048842; GO:0055113; GO:0060971; GO:0060972; GO:0060976; GO:0061371; GO:0071907; GO:0097094; GO:0097155 47448 XR_003828206.2 68 0 0 0 0 NA NA NA NA NA NA 47449 XM_029356180.2 26 0 17 17 79 Q96A58 6.43e-35 Ras-related and estrogen-regulated growth inhibitor (EC 3.6.5.2) Homo sapiens (Human) negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; Ras protein signal transduction [GO:0007265]; response to hormone [GO:0009725]; small GTPase mediated signal transduction [GO:0007264] GO:0001650; GO:0003924; GO:0003925; GO:0005525; GO:0005634; GO:0005654; GO:0005829; GO:0005886; GO:0007264; GO:0007265; GO:0008285; GO:0009725; GO:0019003; GO:0030308; GO:0030331 47450 XM_029346352.2 243 180 327 790 368 NA NA NA NA NA NA 47451 XR_006397032.1 77 86 129 148 101 NA NA NA NA NA NA 47452 XR_006396252.1 0 14 7 0 0 NA NA NA NA NA NA 47453 XR_006391673.1 74 53 39 30 74 NA NA NA NA NA NA 47454 XM_029343793.2 417 393 228 597 387 NA NA NA NA NA NA 47455 XM_044329289.1 144 29 120 100 268 NA NA NA NA NA NA 47456 XR_003828238.2 242 168 248 188 267 NA NA NA NA NA NA 47457 XM_029324577.2 792 868 786 1181 1375 Q92545 0 Transmembrane protein 131 (Protein RW1) Homo sapiens (Human) NA GO:0016020 47458 XM_044320432.1 0 0 2 0 13 P0CT39 4.21e-82 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 47459 XM_029329830.2 0 0 0 10 5 NA NA NA NA NA NA 47460 XR_006394583.1 307 270 224 218 174 F6QEU4 2.82e-91 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 47461 XR_006394583.1 307 270 224 218 174 F6QEU4 2.82e-91 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 47462 XR_006394583.1 307 270 224 218 174 F6QEU4 2.82e-91 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 47463 XR_006394583.1 307 270 224 218 174 F6QEU4 1.3e-28 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 47464 XR_006394583.1 307 270 224 218 174 F6QEU4 3.91e-22 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 47465 XM_044323302.1 287 297 273 173 160 P16157 2.38e-84 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 47466 XM_044323302.1 287 297 273 173 160 P16157 5.15e-75 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 47467 XM_044323302.1 287 297 273 173 160 P16157 1.08e-68 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 47468 XM_044323302.1 287 297 273 173 160 P16157 1.47e-67 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 47469 XM_044323302.1 287 297 273 173 160 P16157 4.36e-36 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 47470 XM_044315276.1 10 2 0 12 0 NA NA NA NA NA NA 47471 XM_029335269.2 24 124 40 60 76 NA NA NA NA NA NA 47472 XM_044321386.1 7 0 7 10 19 NA NA NA NA NA NA 47473 XR_006395352.1 702 56 0 75 12 NA NA NA NA NA NA 47474 XM_044328451.1 0 2 12 0 0 Q49SH1 1.13e-100 Sodium/potassium/calcium exchanger 5 (Na(+)/K(+)/Ca(2+)-exchange protein 5) (Protein golden) (Solute carrier family 24 member 5) Danio rerio (Zebrafish) (Brachydanio rerio) calcium ion transport [GO:0006816]; potassium ion transport [GO:0006813]; response to stimulus [GO:0050896]; sodium ion transport [GO:0006814] GO:0005794; GO:0006813; GO:0006814; GO:0006816; GO:0015293; GO:0015297; GO:0016020; GO:0042470; GO:0050896 47475 XR_006395691.1 11 1 0 4 1 NA NA NA NA NA NA 47476 XM_029341081.2 154 864 565 406 31 Q9JMJ2 6.17e-83 F-box/WD repeat-containing protein 4 (F-box and WD-40 domain-containing protein 4) (Protein hagoromo) Mus musculus (Mouse) cartilage development [GO:0051216]; embryonic digit morphogenesis [GO:0042733]; limb development [GO:0060173]; positive regulation of mesenchymal cell proliferation [GO:0002053]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; Wnt signaling pathway [GO:0016055] GO:0002053; GO:0016055; GO:0019005; GO:0031146; GO:0042733; GO:0051216; GO:0060173 47477 XM_029340444.2 1314 763 540 1254 556 P30349 0 Leukotriene A-4 hydrolase (LTA-4 hydrolase) (EC 3.3.2.6) (Leukotriene A(4) hydrolase) (Tripeptide aminopeptidase LTA4H) (EC 3.4.11.4) Rattus norvegicus (Rat) leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; peptide catabolic process [GO:0043171]; protein metabolic process [GO:0019538]; proteolysis [GO:0006508]; response to peptide hormone [GO:0043434]; response to zinc ion [GO:0010043]; type I pneumocyte differentiation [GO:0060509] GO:0004177; GO:0004301; GO:0004463; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006508; GO:0006691; GO:0008270; GO:0010043; GO:0019370; GO:0019538; GO:0043171; GO:0043434; GO:0045148; GO:0060509; GO:0070006 47478 XM_029339065.2 1903 1218 1116 1650 1308 Q2HJ10 7.85e-103 Proton-coupled zinc antiporter SLC30A2 (Solute carrier family 30 member 2) (Zinc transporter 2) (ZnT-2) Mus musculus (Mouse) cellular zinc ion homeostasis [GO:0006882]; positive regulation of sequestering of zinc ion [GO:0061090]; regulation of sequestering of zinc ion [GO:0061088]; response to zinc ion [GO:0010043]; zinc export across plasma membrane [GO:0140882]; zinc ion import into lysosome [GO:0140916]; zinc ion import into mitochondrion [GO:0140917]; zinc ion import into organelle [GO:0062111]; zinc ion import into zymogen granule [GO:0140915]; zinc ion transmembrane transport [GO:0071577]; zinc ion transport [GO:0006829] GO:0005385; GO:0005737; GO:0005743; GO:0005765; GO:0005770; GO:0005886; GO:0006829; GO:0006882; GO:0010008; GO:0010043; GO:0030658; GO:0031410; GO:0042589; GO:0042802; GO:0043231; GO:0046872; GO:0061088; GO:0061090; GO:0062111; GO:0071577; GO:0099503; GO:0140826; GO:0140882; GO:0140915; GO:0140916; GO:0140917 47479 XM_044325750.1 27 24 33 21 57 NA NA NA NA NA NA 47480 XM_029358272.2 537 223 289 633 338 P34821 1.58e-34 Bone morphogenetic protein 8A (BMP-8A) (Osteogenic protein 2) (OP-2) Mus musculus (Mouse) BMP signaling pathway [GO:0030509]; cartilage development [GO:0051216]; germ cell development [GO:0007281]; osteoblast differentiation [GO:0001649]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; SMAD protein signal transduction [GO:0060395]; spermatogenesis [GO:0007283]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001649; GO:0005125; GO:0005615; GO:0007179; GO:0007281; GO:0007283; GO:0008083; GO:0010862; GO:0030509; GO:0051216; GO:0060395; GO:0070700 47481 XM_044320662.1 20 0 31 1 45 Q61555 2.99e-53 Fibrillin-2 [Cleaved into: Placensin] Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; limb morphogenesis [GO:0035108]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030326; GO:0030501; GO:0031012; GO:0035108; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 47482 XM_044320662.1 20 0 31 1 45 Q61555 8.07e-47 Fibrillin-2 [Cleaved into: Placensin] Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; limb morphogenesis [GO:0035108]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030326; GO:0030501; GO:0031012; GO:0035108; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 47483 XM_044320662.1 20 0 31 1 45 Q61555 1.8e-45 Fibrillin-2 [Cleaved into: Placensin] Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; limb morphogenesis [GO:0035108]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030326; GO:0030501; GO:0031012; GO:0035108; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 47484 XM_044320662.1 20 0 31 1 45 Q61555 2.67e-44 Fibrillin-2 [Cleaved into: Placensin] Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; limb morphogenesis [GO:0035108]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030326; GO:0030501; GO:0031012; GO:0035108; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 47485 XM_044320662.1 20 0 31 1 45 Q61555 4.97e-39 Fibrillin-2 [Cleaved into: Placensin] Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; limb morphogenesis [GO:0035108]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030326; GO:0030501; GO:0031012; GO:0035108; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 47486 XM_044320662.1 20 0 31 1 45 Q61555 1.21e-36 Fibrillin-2 [Cleaved into: Placensin] Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; limb morphogenesis [GO:0035108]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030326; GO:0030501; GO:0031012; GO:0035108; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 47487 XM_044320662.1 20 0 31 1 45 Q61555 2.61e-32 Fibrillin-2 [Cleaved into: Placensin] Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; limb morphogenesis [GO:0035108]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030326; GO:0030501; GO:0031012; GO:0035108; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 47488 XM_044320662.1 20 0 31 1 45 Q61555 1.79e-25 Fibrillin-2 [Cleaved into: Placensin] Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; limb morphogenesis [GO:0035108]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030326; GO:0030501; GO:0031012; GO:0035108; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 47489 XM_044320662.1 20 0 31 1 45 Q61555 7.04e-25 Fibrillin-2 [Cleaved into: Placensin] Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; limb morphogenesis [GO:0035108]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030326; GO:0030501; GO:0031012; GO:0035108; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 47490 XM_044320662.1 20 0 31 1 45 Q61555 4.95e-24 Fibrillin-2 [Cleaved into: Placensin] Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; limb morphogenesis [GO:0035108]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030326; GO:0030501; GO:0031012; GO:0035108; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 47491 XM_044320662.1 20 0 31 1 45 Q61555 3.12e-23 Fibrillin-2 [Cleaved into: Placensin] Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; limb morphogenesis [GO:0035108]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030326; GO:0030501; GO:0031012; GO:0035108; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 47492 XM_044311862.1 87 33 7 19 17 B1H1P9 3.55e-59 Lysosomal acid phosphatase (LAP) (EC 3.1.3.2) Xenopus laevis (African clawed frog) NA GO:0003993; GO:0005765; GO:0043202 47493 XM_029333566.2 1855 1292 943 1351 1314 B6MFW3 0 Protein Hook homolog Branchiostoma floridae (Florida lancelet) (Amphioxus) cytoplasmic microtubule organization [GO:0031122]; cytoskeleton-dependent intracellular transport [GO:0030705]; protein transport [GO:0015031] GO:0005737; GO:0005813; GO:0005874; GO:0008017; GO:0015031; GO:0030705; GO:0031122; GO:0051959 47494 XM_029323634.2 0 14 93 323 763 Q8TCB7 7.09e-111 tRNA N(3)-methylcytidine methyltransferase METTL6 (EC 2.1.1.-) (Methyltransferase-like protein 6) (hMETTL6) Homo sapiens (Human) tRNA methylation [GO:0030488] GO:0005634; GO:0005737; GO:0019899; GO:0030488; GO:0052735 47495 XM_044314180.1 1 0 0 7 0 NA NA NA NA NA NA 47496 XM_029356307.2 2058 2126 1701 2242 1546 NA NA NA NA NA NA 47497 XM_044313161.1 49 0 0 0 47 P18130 2.97e-31 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) Bos taurus (Bovine) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of vasoconstriction [GO:0045907]; regulation of cardiac muscle contraction [GO:0055117] GO:0001996; GO:0004930; GO:0004937; GO:0005634; GO:0005737; GO:0005886; GO:0005901; GO:0007200; GO:0007204; GO:0007267; GO:0031965; GO:0043410; GO:0045907; GO:0046982; GO:0055117; GO:0071880 47498 XM_044315013.1 45 131 42 108 127 NA NA NA NA NA NA 47499 XM_029349985.2 12 0 19 1 31 NA NA NA NA NA NA 47500 XM_044324209.1 0 0 2 8 0 G8XYX6 1.07e-52 Monocarboxylate transporter 8 (MCT 8) (Solute carrier family 16 member 2) Danio rerio (Zebrafish) (Brachydanio rerio) brain development [GO:0007420]; central nervous system development [GO:0007417]; chordate embryonic development [GO:0043009]; locomotion [GO:0040011]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; Schwann cell differentiation [GO:0014037]; spinal cord development [GO:0021510]; spinal cord oligodendrocyte cell differentiation [GO:0021529]; thyroid gland development [GO:0030878] GO:0007417; GO:0007420; GO:0014037; GO:0015349; GO:0016324; GO:0021510; GO:0021529; GO:0030182; GO:0030878; GO:0040011; GO:0043009; GO:0048709; GO:0070324 47501 XM_029339572.2 251 671 126 209 294 NA NA NA NA NA NA 47502 XM_044323574.1 4233 3990 83 33 2076 NA NA NA NA NA NA 47503 XM_029337659.2 0 0 0 8 9 O88871 3.82e-117 Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51) Rattus norvegicus (Rat) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; gamma-aminobutyric acid signaling pathway [GO:0007214]; neuron-glial cell signaling [GO:0150099]; synaptic transmission, GABAergic [GO:0051932] GO:0004888; GO:0004965; GO:0005737; GO:0005886; GO:0007193; GO:0007214; GO:0016020; GO:0030425; GO:0038039; GO:0042734; GO:0043005; GO:0043204; GO:0045211; GO:0046982; GO:0051932; GO:0098978; GO:0098982; GO:0150099; GO:1902710; GO:1902712 47504 XM_044308932.1 0 0 2 1 17 NA NA NA NA NA NA 47505 XM_044316573.1 396 98 4162 867 20301 NA NA NA NA NA NA 47506 XM_029331608.2 1450 761 767 1713 1911 Q9NRL2 1.1e-47 Bromodomain adjacent to zinc finger domain protein 1A (ATP-dependent chromatin-remodeling protein) (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (CHRAC subunit ACF1) (Williams syndrome transcription factor-related chromatin-remodeling factor 180) (WCRF180) (hWALp1) Homo sapiens (Human) chromatin remodeling [GO:0006338]; DNA-templated DNA replication [GO:0006261]; nucleosome assembly [GO:0006334]; positive regulation of DNA replication [GO:0045740]; regulation of DNA replication [GO:0006275]; regulation of DNA-templated transcription [GO:0006355]; regulation of heterochromatin formation [GO:0031445]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000228; GO:0003677; GO:0005634; GO:0005721; GO:0006261; GO:0006275; GO:0006334; GO:0006338; GO:0006355; GO:0006357; GO:0008623; GO:0016590; GO:0031445; GO:0045740; GO:0046872 47507 XM_029331608.2 1450 761 767 1713 1911 Q9NRL2 7.78e-39 Bromodomain adjacent to zinc finger domain protein 1A (ATP-dependent chromatin-remodeling protein) (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (CHRAC subunit ACF1) (Williams syndrome transcription factor-related chromatin-remodeling factor 180) (WCRF180) (hWALp1) Homo sapiens (Human) chromatin remodeling [GO:0006338]; DNA-templated DNA replication [GO:0006261]; nucleosome assembly [GO:0006334]; positive regulation of DNA replication [GO:0045740]; regulation of DNA replication [GO:0006275]; regulation of DNA-templated transcription [GO:0006355]; regulation of heterochromatin formation [GO:0031445]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000228; GO:0003677; GO:0005634; GO:0005721; GO:0006261; GO:0006275; GO:0006334; GO:0006338; GO:0006355; GO:0006357; GO:0008623; GO:0016590; GO:0031445; GO:0045740; GO:0046872 47508 XM_029331608.2 1450 761 767 1713 1911 Q9NRL2 3.08e-33 Bromodomain adjacent to zinc finger domain protein 1A (ATP-dependent chromatin-remodeling protein) (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (CHRAC subunit ACF1) (Williams syndrome transcription factor-related chromatin-remodeling factor 180) (WCRF180) (hWALp1) Homo sapiens (Human) chromatin remodeling [GO:0006338]; DNA-templated DNA replication [GO:0006261]; nucleosome assembly [GO:0006334]; positive regulation of DNA replication [GO:0045740]; regulation of DNA replication [GO:0006275]; regulation of DNA-templated transcription [GO:0006355]; regulation of heterochromatin formation [GO:0031445]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000228; GO:0003677; GO:0005634; GO:0005721; GO:0006261; GO:0006275; GO:0006334; GO:0006338; GO:0006355; GO:0006357; GO:0008623; GO:0016590; GO:0031445; GO:0045740; GO:0046872 47509 XM_029351904.2 660 345 141 367 267 Q9H892 1.33e-75 Tetratricopeptide repeat protein 12 (TPR repeat protein 12) Homo sapiens (Human) axonemal dynein complex assembly [GO:0070286]; sperm axoneme assembly [GO:0007288] GO:0005737; GO:0005813; GO:0007288; GO:0070286 47510 XM_029328460.2 13 14 7 8 0 NA NA NA NA NA NA 47511 XM_029329895.2 8 2 4 4 24 Q3ZBY7 1.95e-133 Sphingolipid delta(4)-desaturase DES1 (EC 1.14.19.17) (Degenerative spermatocyte homolog 1) (Dihydroceramide desaturase-1) (Retinol isomerase) (EC 5.2.1.-) Bos taurus (Bovine) ceramide biosynthetic process [GO:0046513]; fatty acid biosynthetic process [GO:0006633]; myelin maintenance [GO:0043217] GO:0005789; GO:0006633; GO:0016859; GO:0031966; GO:0042284; GO:0043217; GO:0046513; GO:0050251 47512 XM_029332303.2 29268 20804 19768 33292 31958 NA NA NA NA NA NA 47513 XM_029338061.2 2 2 6 2 0 NA NA NA NA NA NA 47514 XM_044317572.1 11 12 24 20 92 Q5VVH5 4.18e-51 Interleukin-1 receptor-associated kinase 1-binding protein 1 (IRAK1-binding protein 1) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; immune response [GO:0006955] GO:0005634; GO:0005737; GO:0006955; GO:0007249 47515 XM_029345776.2 8467 19013 8543 15480 9440 NA NA NA NA NA NA 47516 XM_029347928.2 190 123 225 246 223 Q2QRV3 3.6e-109 Alpha-dioxygenase PIOX (EC 1.13.11.92) (Pathogen-induced oxygenase) Oryza sativa subsp. japonica (Rice) (R)-2-hydroxy-alpha-linolenic acid biosynthetic process [GO:1902609]; cell death [GO:0008219]; cellular response to nitric oxide [GO:0071732]; cellular response to reactive oxygen species [GO:0034614]; cellular response to salicylic acid stimulus [GO:0071446]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; fatty acid alpha-oxidation [GO:0001561]; oxylipin biosynthetic process [GO:0031408]; response to abscisic acid [GO:0009737]; systemic acquired resistance [GO:0009627] GO:0001561; GO:0004601; GO:0008219; GO:0009627; GO:0009737; GO:0012511; GO:0016702; GO:0020037; GO:0031408; GO:0034614; GO:0042742; GO:0046872; GO:0050832; GO:0071446; GO:0071732; GO:1902609 47517 XM_044329021.1 13 24 44 81 20 Q8K2J9 7.35e-83 BTB/POZ domain-containing protein 6 Mus musculus (Mouse) neurogenesis [GO:0022008] GO:0005829; GO:0022008 47518 XM_044324757.1 0 0 0 14 0 NA NA NA NA NA NA 47519 XR_006394445.1 4 28 12 0 7 NA NA NA NA NA NA 47520 XM_044311497.1 23 16 11 19 2 NA NA NA NA NA NA 47521 XM_044321808.1 2 11 0 6 2 NA NA NA NA NA NA 47522 XM_029333466.2 80 136 118 108 88 Q05B60 3.52e-50 Uridine diphosphate glucose pyrophosphatase NUDT14 (UDPG pyrophosphatase) (UGPPase) (EC 3.6.1.45) (Nucleoside diphosphate-linked moiety X motif 14) (Nudix motif 14) Bos taurus (Bovine) nucleoside phosphate metabolic process [GO:0006753]; ribose phosphate metabolic process [GO:0019693] GO:0005737; GO:0006753; GO:0008768; GO:0019693; GO:0042802; GO:0046872; GO:0047631 47523 XM_044328698.1 445 338 237 343 346 NA NA NA NA NA NA 47524 XM_044318602.1 547 557 399 669 555 Q3SYV5 1e-68 Tetraspanin-33 (Tspan-33) Bos taurus (Bovine) NA GO:0005737; GO:0005886; GO:0005912 47525 XM_029358491.2 739 457 464 632 598 NA NA NA NA NA NA 47526 XM_044328942.1 12 42 5 17 23 Q505B7 1.64e-35 Protein archease (Protein ZBTB8OS) Mus musculus (Mouse) tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388] GO:0006388; GO:0046872; GO:0072669 47527 XM_044326445.1 19 0 15 8 27 NA NA NA NA NA NA 47528 XM_044309073.1 20 11 3 6 2 NA NA NA NA NA NA 47529 XM_029354467.2 283 178 146 292 354 Q8N801 9.22e-37 Protein STPG4 (Gonad-specific expression gene protein) (GSE) (Sperm-tail PG-rich repeat-containing protein 4) Homo sapiens (Human) C-5 methylation of cytosine [GO:0090116]; chromatin organization [GO:0006325]; DNA demethylation of male pronucleus [GO:0044727]; positive regulation of DNA demethylation [GO:1901537] GO:0001673; GO:0001939; GO:0001940; GO:0003682; GO:0005634; GO:0005737; GO:0006325; GO:0042393; GO:0042585; GO:0044727; GO:0090116; GO:1901537 47530 XM_029333386.2 319 157 222 254 136 Q5EBF1 0 Cytosolic purine 5'-nucleotidase (EC 3.1.3.5) (EC 3.1.3.99) (Cytosolic nucleoside phosphotransferase 5'N) (EC 2.7.1.77) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) dGMP metabolic process [GO:0046054]; GMP metabolic process [GO:0046037]; IMP metabolic process [GO:0046040] GO:0005524; GO:0005829; GO:0008253; GO:0042802; GO:0046037; GO:0046040; GO:0046054; GO:0046872; GO:0050146; GO:0050483; GO:0050484; GO:0106411 47531 XM_044327126.1 6 38 66 0 0 NA NA NA NA NA NA 47532 XR_006395194.1 6 0 1 0 5 NA NA NA NA NA NA 47533 XM_029342042.2 520 189 813 683 931 Q28772 2.23e-31 Transcription factor 12 (TCF-12) (DNA-binding protein HTF4) (E-box-binding protein) (Transcription factor HTF-4) Papio hamadryas (Hamadryas baboon) cell differentiation [GO:0030154]; nervous system development [GO:0007399]; positive regulation of neuron differentiation [GO:0045666]; response to gonadotropin-releasing hormone [GO:0097210] GO:0005634; GO:0007399; GO:0030154; GO:0045666; GO:0046982; GO:0070888; GO:0097210 47534 XM_029358728.2 167 189 164 201 147 Q08BG1 4.01e-85 Transmembrane protein with metallophosphoesterase domain (EC 3.1.-.-) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0016020; GO:0016787; GO:0046872 47535 XR_006392337.1 757 556 392 242 825 NA NA NA NA NA NA 47536 XM_044312722.1 20 1 0 3 0 Q9JK91 0 DNA mismatch repair protein Mlh1 (MutL protein homolog 1) Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; female meiosis chromosome segregation [GO:0016321]; homologous chromosome pairing at meiosis [GO:0007129]; homologous chromosome segregation [GO:0045143]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; isotype switching [GO:0045190]; male meiosis chromosome segregation [GO:0007060]; male meiotic nuclear division [GO:0007140]; meiotic cell cycle [GO:0051321]; meiotic chromosome segregation [GO:0045132]; meiotic metaphase I plate congression [GO:0043060]; meiotic spindle midzone assembly [GO:0051257]; meiotic telomere clustering [GO:0045141]; mismatch repair [GO:0006298]; negative regulation of mitotic recombination [GO:0045950]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; oogenesis [GO:0048477]; positive regulation of isotype switching to IgA isotypes [GO:0048298]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; reciprocal meiotic recombination [GO:0007131]; resolution of meiotic recombination intermediates [GO:0000712]; response to bacterium [GO:0009617]; somatic hypermutation of immunoglobulin genes [GO:0016446]; somatic recombination of immunoglobulin gene segments [GO:0016447]; somatic recombination of immunoglobulin genes involved in immune response [GO:0002204]; spermatogenesis [GO:0007283] GO:0000289; GO:0000712; GO:0000793; GO:0000794; GO:0000795; GO:0001673; GO:0002204; GO:0003682; GO:0003697; GO:0005524; GO:0005634; GO:0005654; GO:0005694; GO:0005712; GO:0005715; GO:0006281; GO:0006298; GO:0006303; GO:0006974; GO:0007060; GO:0007129; GO:0007131; GO:0007140; GO:0007283; GO:0008630; GO:0009617; GO:0016321; GO:0016446; GO:0016447; GO:0016887; GO:0019899; GO:0032137; GO:0032300; GO:0032389; GO:0032407; GO:0043060; GO:0045132; GO:0045141; GO:0045143; GO:0045190; GO:0045950; GO:0048298; GO:0048304; GO:0048477; GO:0051257; GO:0051321; GO:0140664 47537 XR_003824697.2 39 0 0 18 15 NA NA NA NA NA NA 47538 XR_006395256.1 22 63 31 14 36 NA NA NA NA NA NA 47539 XM_044323366.1 0 0 0 53 72 Q15119 4.9e-101 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 2) (PDH kinase 2) (PDKII) Homo sapiens (Human) cellular response to nutrient [GO:0031670]; cellular response to reactive oxygen species [GO:0034614]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; insulin receptor signaling pathway [GO:0008286]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; protein phosphorylation [GO:0006468]; regulation of acetyl-CoA biosynthetic process from pyruvate [GO:0010510]; regulation of calcium-mediated signaling [GO:0050848]; regulation of cellular ketone metabolic process [GO:0010565]; regulation of gluconeogenesis [GO:0006111]; regulation of glucose metabolic process [GO:0010906]; regulation of pH [GO:0006885] GO:0004672; GO:0004740; GO:0005524; GO:0005654; GO:0005739; GO:0005759; GO:0005829; GO:0005967; GO:0006006; GO:0006111; GO:0006468; GO:0006885; GO:0008286; GO:0010510; GO:0010565; GO:0010906; GO:0031670; GO:0034614; GO:0042593; GO:0042803; GO:0050848; GO:0072332 47540 XM_044323366.1 0 0 0 53 72 Q15119 4.9e-101 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 2) (PDH kinase 2) (PDKII) Homo sapiens (Human) cellular response to nutrient [GO:0031670]; cellular response to reactive oxygen species [GO:0034614]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; insulin receptor signaling pathway [GO:0008286]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; protein phosphorylation [GO:0006468]; regulation of acetyl-CoA biosynthetic process from pyruvate [GO:0010510]; regulation of calcium-mediated signaling [GO:0050848]; regulation of cellular ketone metabolic process [GO:0010565]; regulation of gluconeogenesis [GO:0006111]; regulation of glucose metabolic process [GO:0010906]; regulation of pH [GO:0006885] GO:0004672; GO:0004740; GO:0005524; GO:0005654; GO:0005739; GO:0005759; GO:0005829; GO:0005967; GO:0006006; GO:0006111; GO:0006468; GO:0006885; GO:0008286; GO:0010510; GO:0010565; GO:0010906; GO:0031670; GO:0034614; GO:0042593; GO:0042803; GO:0050848; GO:0072332 47541 XM_044319842.1 1191 426 679 947 833 Q9GYZ0 0 Kinesin-like protein KIF15 (Kinesin-related protein KRP180) Strongylocentrotus purpuratus (Purple sea urchin) microtubule-based movement [GO:0007018]; regulation of mitotic spindle assembly [GO:1901673] GO:0003777; GO:0005524; GO:0005737; GO:0005819; GO:0005871; GO:0005874; GO:0007018; GO:0008017; GO:0016887; GO:1901673 47542 XM_029332847.2 2873 1983 1593 1708 1269 A3KCL7 2.15e-68 D-aspartate oxidase (DASOX) (DDO) (EC 1.4.3.1) Sus scrofa (Pig) aspartate catabolic process [GO:0006533]; D-amino acid catabolic process [GO:0019478] GO:0003884; GO:0005737; GO:0005777; GO:0006533; GO:0008445; GO:0019478; GO:0071949 47543 XR_006392879.1 41 2 25 5 151 NA NA NA NA NA NA 47544 XM_029352295.2 463 720 480 821 854 Q62849 0 Proprotein convertase subtilisin/kexin type 7 (EC 3.4.21.-) (Prohormone convertase 7) (Proprotein convertase 7) (PC7) (rPC7) (Subtilisin/kexin-like protease PC7) Rattus norvegicus (Rat) protein processing [GO:0016485] GO:0000139; GO:0004252; GO:0005802; GO:0008233; GO:0016020; GO:0016485 47545 XM_029346943.2 146 113 115 135 106 Q5RF65 1.88e-158 Cytosolic beta-glucosidase (EC 3.2.1.21) (Cytosolic galactosylceramidase) (EC 3.2.1.46) (Cytosolic glucosylceramidase) (EC 3.2.1.45) (Cytosolic glycosylceramidase) (Cytosolic GCase) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) beta-glucoside catabolic process [GO:1901805]; carbohydrate metabolic process [GO:0005975]; galactosylceramide catabolic process [GO:0006683]; glucosylceramide catabolic process [GO:0006680] GO:0004336; GO:0004348; GO:0004565; GO:0005829; GO:0005975; GO:0006680; GO:0006683; GO:0008422; GO:0017042; GO:0102483; GO:1901805 47546 XR_006391474.1 74 0 0 18 22 NA NA NA NA NA NA 47547 XM_044310931.1 0 2284 39 0 0 NA NA NA NA NA NA 47548 XM_044320178.1 1 0 0 0 11 NA NA NA NA NA NA 47549 XM_029341575.2 2715 2259 1458 1866 1692 Q9JJX8 1.16e-144 Serine/threonine-protein kinase 32B (EC 2.7.11.1) Mus musculus (Mouse) intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105] GO:0004674; GO:0005524; GO:0018105; GO:0035556; GO:0046872; GO:0106310 47550 XM_044314218.1 0 0 0 120 0 NA NA NA NA NA NA 47551 XM_029357665.2 19 0 0 117 0 NA NA NA NA NA NA 47552 XM_029342578.2 1880 1697 1605 2457 3483 Q66LN0 5.04e-78 Prostaglandin E synthase 2 (EC 5.3.99.3) (Membrane-associated prostaglandin E synthase-2) (mPGE synthase-2) (Microsomal prostaglandin E synthase 2) (mPGES-2) [Cleaved into: Prostaglandin E synthase 2 truncated form] Bos taurus (Bovine) prostaglandin biosynthetic process [GO:0001516] GO:0001516; GO:0005739; GO:0005783; GO:0016020; GO:0016829; GO:0020037; GO:0036134; GO:0043295; GO:0050220 47553 XM_044307511.1 70 73 76 218 128 NA NA NA NA NA NA 47554 XR_006393332.1 2 0 2 1 28 NA NA NA NA NA NA 47555 XM_029339904.2 924 1215 699 1148 1044 Q96DI7 5.98e-177 U5 small nuclear ribonucleoprotein 40 kDa protein (U5 snRNP 40 kDa protein) (U5-40K) (38 kDa-splicing factor) (Prp8-binding protein) (hPRP8BP) (U5 snRNP-specific 40 kDa protein) (WD repeat-containing protein 57) Homo sapiens (Human) mRNA splicing, via spliceosome [GO:0000398]; RNA processing [GO:0006396]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375] GO:0000375; GO:0000398; GO:0003723; GO:0005634; GO:0005654; GO:0005682; GO:0005732; GO:0005829; GO:0006396; GO:0008380; GO:0016607; GO:0046540; GO:0071007; GO:0071013 47556 XM_044326104.1 0 1 9 0 0 NA NA NA NA NA NA 47557 XM_044322020.1 847 267 1241 1158 2803 P20072 2.7e-130 Annexin A7 (Annexin VII) (Annexin-7) (Synexin) Bos taurus (Bovine) NA GO:0005509; GO:0005544; GO:0005634; GO:0005737; GO:0042584 47558 XM_029344236.2 147 139 47 53 52 Q5D1E7 3.48e-80 Endoribonuclease ZC3H12A (EC 3.1.-.-) (Monocyte chemotactic protein-induced protein 1) (MCP-induced protein 1) (MCPIP-1) (Regnase-1) (Reg1) (Zinc finger CCCH domain-containing protein 12A) Mus musculus (Mouse) 3'-UTR-mediated mRNA destabilization [GO:0061158]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; cellular response to chemokine [GO:1990869]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to glucose starvation [GO:0042149]; cellular response to interleukin-1 [GO:0071347]; cellular response to ionomycin [GO:1904637]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; cellular response to sodium arsenite [GO:1903936]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to virus [GO:0098586]; immune response-activating signaling pathway [GO:0002757]; inflammatory response [GO:0006954]; miRNA catabolic process [GO:0010587]; negative regulation by host of viral genome replication [GO:0044828]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of gene expression [GO:0010629]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T-helper 17 cell differentiation [GO:2000320]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; nervous system development [GO:0007399]; nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay [GO:0000294]; positive regulation of angiogenesis [GO:0045766]; positive regulation of autophagy [GO:0010508]; positive regulation of cell death [GO:0010942]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of gene expression [GO:0010628]; positive regulation of lipid storage [GO:0010884]; positive regulation of miRNA catabolic process [GO:2000627]; positive regulation of mRNA catabolic process [GO:0061014]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of protein deubiquitination [GO:1903003]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein complex oligomerization [GO:0051259]; protein deubiquitination [GO:0016579]; regulation of gene expression [GO:0010468]; RNA phosphodiester bond hydrolysis [GO:0090501]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; T cell receptor signaling pathway [GO:0050852] GO:0000294; GO:0000932; GO:0001525; GO:0001933; GO:0002230; GO:0002757; GO:0003677; GO:0003682; GO:0003723; GO:0003729; GO:0003730; GO:0004518; GO:0004521; GO:0004532; GO:0004540; GO:0004843; GO:0005634; GO:0005654; GO:0005737; GO:0005791; GO:0005856; GO:0006915; GO:0006954; GO:0006974; GO:0007399; GO:0010468; GO:0010508; GO:0010587; GO:0010595; GO:0010628; GO:0010629; GO:0010656; GO:0010884; GO:0010942; GO:0016579; GO:0030154; GO:0030867; GO:0032088; GO:0032689; GO:0032691; GO:0032715; GO:0032720; GO:0032991; GO:0034599; GO:0035198; GO:0035613; GO:0035925; GO:0036464; GO:0042149; GO:0042307; GO:0042406; GO:0043022; GO:0043124; GO:0044828; GO:0045019; GO:0045600; GO:0045766; GO:0045944; GO:0046872; GO:0050852; GO:0051259; GO:0055118; GO:0061014; GO:0061158; GO:0071222; GO:0071347; GO:0071356; GO:0090501; GO:0090502; GO:0098586; GO:1900016; GO:1900119; GO:1900745; GO:1901223; GO:1903003; GO:1903936; GO:1904637; GO:1990869; GO:2000320; GO:2000379; GO:2000627 47559 XR_006395212.1 174 103 47 151 3 NA NA NA NA NA NA 47560 XM_044320205.1 204 0 261 0 0 NA NA NA NA NA NA 47561 XM_029328971.2 0 0 0 41 147 NA NA NA NA NA NA 47562 XM_044317464.1 0 0 0 0 6 NA NA NA NA NA NA 47563 XM_044328672.1 724 412 171 606 514 Q6V0K7 7.62e-50 Oncoprotein-induced transcript 3 protein (Liver-specific zona pellucida domain-containing protein) Rattus norvegicus (Rat) urate homeostasis [GO:1903118] GO:0005201; GO:0005509; GO:0005615; GO:0005635; GO:0009986; GO:1903118 47564 XM_029349201.2 197 257 136 330 254 Q6DIV6 1.62e-43 Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Solute carrier family 32 member 1) (Vesicular GABA transporter) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) beta-alanine transport [GO:0001762]; gamma-aminobutyric acid import [GO:0051939]; gamma-aminobutyric acid transport [GO:0015812]; glycine transport [GO:0015816]; neurotransmitter transport [GO:0006836] GO:0001762; GO:0006836; GO:0008021; GO:0015185; GO:0015187; GO:0015812; GO:0015816; GO:0030659; GO:0042995; GO:0051939; GO:0098793; GO:0140799; GO:0140800 47565 XM_029329869.2 952 2897 1251 1208 1380 Q91VW3 3.17e-21 SH3 domain-binding glutamic acid-rich-like protein 3 Mus musculus (Mouse) cytoskeleton organization [GO:0007010] GO:0005829; GO:0007010; GO:0016604; GO:0032587 47566 XM_044326431.1 7 0 2 0 2 NA NA NA NA NA NA 47567 XM_044314334.1 0 0 0 3 18 P35067 1.51e-84 Histone H2B Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 47568 XM_044311847.1 273 150 97 402 540 F8S101 1.17e-28 Phospholipase B (PLB) (EC 3.1.1.-) Crotalus adamanteus (Eastern diamondback rattlesnake) hemolysis in another organism [GO:0044179]; lipid catabolic process [GO:0016042] GO:0004620; GO:0005576; GO:0016042; GO:0044179; GO:0090729 47569 XM_044311122.1 107 12 267 151 307 NA NA NA NA NA NA 47570 XM_044310930.1 123 189 81 52 261 NA NA NA NA NA NA 47571 XM_044318232.1 89 66 137 41 165 E7FAM5 8.72e-91 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 47572 XR_006392490.1 7 4 6 23 7 NA NA NA NA NA NA 47573 XM_044327894.1 1225 415 565 576 797 NA NA NA NA NA NA 47574 XM_029339230.2 24 0 0 0 0 NA NA NA NA NA NA 47575 XM_029351373.2 35 0 21 46 29 NA NA NA NA NA NA 47576 XM_029333760.2 247 146 71 440 512 F1NZI4 4.88e-136 Protein-glucosylgalactosylhydroxylysine glucosidase (EC 3.2.1.107) (Acid trehalase-like protein 1) Gallus gallus (Chicken) carbohydrate metabolic process [GO:0005975] GO:0004553; GO:0005829; GO:0005975; GO:0047402 47577 XM_044313978.1 17 41 18 54 26 NA NA NA NA NA NA 47578 XM_029344435.2 1852 904 854 1729 1504 NA NA NA NA NA NA 47579 XM_029352205.2 11 15 0 15 5 Q09575 1.27e-54 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 47580 XM_044320781.1 44 51 24 83 61 Q96AY4 4.13e-84 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 47581 XM_044320781.1 44 51 24 83 61 Q96AY4 6.97e-81 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 47582 XM_044320781.1 44 51 24 83 61 Q96AY4 1.41e-79 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 47583 XM_044320781.1 44 51 24 83 61 Q96AY4 1.16e-78 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 47584 XM_044320781.1 44 51 24 83 61 Q96AY4 5.21e-78 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 47585 XM_044320781.1 44 51 24 83 61 Q96AY4 1.23e-77 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 47586 XM_044320781.1 44 51 24 83 61 Q96AY4 4.74e-37 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 47587 XM_044320781.1 44 51 24 83 61 Q96AY4 5.21e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 47588 XM_044316857.1 431 342 181 336 291 Q9SZJ2 1.14e-53 Glycine-rich domain-containing protein 2 (AtGRDP2) Arabidopsis thaliana (Mouse-ear cress) auxin-activated signaling pathway [GO:0009734]; cellular response to osmotic stress [GO:0071470]; regulation of auxin mediated signaling pathway [GO:0010928]; regulation of photoperiodism, flowering [GO:2000028] GO:0009734; GO:0010928; GO:0071470; GO:2000028 47589 XM_029332223.2 670 762 574 534 355 Q9HC07 9.94e-84 Transmembrane protein 165 (Transmembrane protein PT27) (Transmembrane protein TPARL) Homo sapiens (Human) calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; Golgi calcium ion homeostasis [GO:0032468]; Golgi calcium ion transport [GO:0032472]; manganese ion transmembrane transport [GO:0071421]; protein N-linked glycosylation [GO:0006487]; regulation of lysosomal lumen pH [GO:0035751] GO:0000139; GO:0005384; GO:0005765; GO:0005794; GO:0006487; GO:0006874; GO:0010008; GO:0015085; GO:0031901; GO:0031902; GO:0032468; GO:0032472; GO:0032588; GO:0035751; GO:0043231; GO:0046873; GO:0070588; GO:0071421 47590 XM_044312512.1 13 2 1 6 16 O02751 2.22e-22 Craniofacial development protein 2 (p97 bucentaur protein) Bos taurus (Bovine) chromatin remodeling [GO:0006338] GO:0003824; GO:0005634; GO:0005737; GO:0006338 47591 XM_044314632.1 0 0 0 0 15 NA NA NA NA NA NA 47592 XM_029357499.2 57 69 0 231 17 P23824 7.25e-70 GATA-binding factor 2 (GATA-2) (Transcription factor NF-E1b) Gallus gallus (Chicken) cell fate commitment [GO:0045165]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of angiogenesis [GO:0045766]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000122; GO:0000978; GO:0000981; GO:0001223; GO:0005634; GO:0008270; GO:0045165; GO:0045766; GO:0045944; GO:1902895 47593 XM_044327798.1 78 36 27 79 107 Q8AV58 7.18e-62 Protein sidekick-1 Gallus gallus (Chicken) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; retina layer formation [GO:0010842]; synapse assembly [GO:0007416] GO:0005886; GO:0007156; GO:0007416; GO:0010842; GO:0042802; GO:0045202 47594 XM_044327798.1 78 36 27 79 107 Q8AV58 2.13e-54 Protein sidekick-1 Gallus gallus (Chicken) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; retina layer formation [GO:0010842]; synapse assembly [GO:0007416] GO:0005886; GO:0007156; GO:0007416; GO:0010842; GO:0042802; GO:0045202 47595 XM_044327798.1 78 36 27 79 107 Q8AV58 3.42e-52 Protein sidekick-1 Gallus gallus (Chicken) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; retina layer formation [GO:0010842]; synapse assembly [GO:0007416] GO:0005886; GO:0007156; GO:0007416; GO:0010842; GO:0042802; GO:0045202 47596 XM_044327798.1 78 36 27 79 107 Q8AV58 6.43e-46 Protein sidekick-1 Gallus gallus (Chicken) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; retina layer formation [GO:0010842]; synapse assembly [GO:0007416] GO:0005886; GO:0007156; GO:0007416; GO:0010842; GO:0042802; GO:0045202 47597 XM_044327798.1 78 36 27 79 107 Q8AV58 1.94e-45 Protein sidekick-1 Gallus gallus (Chicken) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; retina layer formation [GO:0010842]; synapse assembly [GO:0007416] GO:0005886; GO:0007156; GO:0007416; GO:0010842; GO:0042802; GO:0045202 47598 XM_044327798.1 78 36 27 79 107 Q8AV58 1.56e-27 Protein sidekick-1 Gallus gallus (Chicken) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; retina layer formation [GO:0010842]; synapse assembly [GO:0007416] GO:0005886; GO:0007156; GO:0007416; GO:0010842; GO:0042802; GO:0045202 47599 XM_029331046.2 0 0 0 0 13 F1N2N9 3.29e-43 Outer dynein arm-docking complex subunit 1 Bos taurus (Bovine) cilium movement [GO:0003341]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0005930; GO:0036158; GO:0120228 47600 XM_044318446.1 11 4 0 0 19 NA NA NA NA NA NA 47601 XM_044322690.1 233 144 88 319 289 Q95LU3 3.1e-65 Fibrinogen C domain-containing protein 1 Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0008061; GO:0016020; GO:0046872 47602 XM_044319767.1 28 16 87 8 167 Q8CG08 1.71e-34 Collagen triple helix repeat-containing protein 1 Rattus norvegicus (Rat) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005581; GO:0005615; GO:0005737; GO:0016477; GO:0016528; GO:0017147; GO:0031012; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0090090; GO:0090103; GO:0090177 47603 XR_006396668.1 8 10 13 45 13 NA NA NA NA NA NA 47604 XM_044315370.1 0 7 2 0 5 NA NA NA NA NA NA 47605 XR_006391331.1 6 0 0 2 0 NA NA NA NA NA NA 47606 XM_029356987.2 212 223 58 291 254 P30975 1.5e-21 Tachykinin-like peptides receptor 99D (Tachykinin-like receptor at 99D) (dTKR) Drosophila melanogaster (Fruit fly) detection of chemical stimulus involved in sensory perception of smell [GO:0050911]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; neuropeptide signaling pathway [GO:0007218]; olfactory behavior [GO:0042048]; positive regulation of sensory perception of pain [GO:1904058]; tachykinin receptor signaling pathway [GO:0007217] GO:0004995; GO:0005886; GO:0007186; GO:0007217; GO:0007218; GO:0008188; GO:0016020; GO:0042048; GO:0050805; GO:0050911; GO:1904058 47607 XM_029337872.2 391 403 211 366 420 B4F7A7 9.44e-65 Centrosomal protein of 57 kDa (Cep57) (Translokin) Rattus norvegicus (Rat) fibroblast growth factor receptor signaling pathway [GO:0008543]; protein homooligomerization [GO:0051260]; spermatid development [GO:0007286] GO:0005634; GO:0005737; GO:0005794; GO:0005813; GO:0005874; GO:0007286; GO:0008017; GO:0008543; GO:0017134; GO:0042803; GO:0043015; GO:0051260 47608 XM_029357615.2 7658 24910 10552 11994 7070 Q95V84 7.4e-27 60S ribosomal protein L38 Branchiostoma belcheri (Amphioxus) translation [GO:0006412] GO:0003735; GO:0005840; GO:0006412; GO:1990904 47609 XM_029355993.2 0 26 1 193 251 NA NA NA NA NA NA 47610 XR_006394482.1 0 0 0 0 11 NA NA NA NA NA NA 47611 XR_006396158.1 81 50 32 39 70 P55011 0 Solute carrier family 12 member 2 (Basolateral Na-K-Cl symporter) (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2) Homo sapiens (Human) aging [GO:0007568]; ammonium transmembrane transport [GO:0072488]; cell volume homeostasis [GO:0006884]; cellular chloride ion homeostasis [GO:0030644]; cellular potassium ion homeostasis [GO:0030007]; cellular response to chemokine [GO:1990869]; cellular response to potassium ion [GO:0035865]; cellular sodium ion homeostasis [GO:0006883]; chloride ion homeostasis [GO:0055064]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid signaling pathway [GO:0007214]; hyperosmotic response [GO:0006972]; inorganic anion import across plasma membrane [GO:0098658]; inorganic cation import across plasma membrane [GO:0098659]; ion transport [GO:0006811]; maintenance of blood-brain barrier [GO:0035633]; negative regulation of vascular wound healing [GO:0061044]; positive regulation of aspartate secretion [GO:1904450]; positive regulation of cell volume [GO:0045795]; potassium ion homeostasis [GO:0055075]; potassium ion import across plasma membrane [GO:1990573]; regulation of matrix metallopeptidase secretion [GO:1904464]; regulation of spontaneous synaptic transmission [GO:0150003]; sodium ion homeostasis [GO:0055078]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725]; T cell chemotaxis [GO:0010818]; transepithelial ammonium transport [GO:0070634]; transepithelial chloride transport [GO:0030321]; transport across blood-brain barrier [GO:0150104] GO:0005829; GO:0005886; GO:0006811; GO:0006883; GO:0006884; GO:0006972; GO:0007214; GO:0007568; GO:0008511; GO:0008519; GO:0009925; GO:0010818; GO:0015079; GO:0015377; GO:0015379; GO:0016020; GO:0016323; GO:0016324; GO:0016328; GO:0019901; GO:0030007; GO:0030321; GO:0030644; GO:0030659; GO:0031253; GO:0035633; GO:0035725; GO:0035865; GO:0042995; GO:0043005; GO:0043025; GO:0044297; GO:0044298; GO:0045795; GO:0046873; GO:0051087; GO:0051879; GO:0055064; GO:0055075; GO:0055078; GO:0061044; GO:0070062; GO:0070634; GO:0071944; GO:0072488; GO:0098658; GO:0098659; GO:0098719; GO:0150003; GO:0150104; GO:1902476; GO:1903561; GO:1904450; GO:1904464; GO:1990573; GO:1990869 47612 XR_006396158.1 81 50 32 39 70 P55011 0 Solute carrier family 12 member 2 (Basolateral Na-K-Cl symporter) (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2) Homo sapiens (Human) aging [GO:0007568]; ammonium transmembrane transport [GO:0072488]; cell volume homeostasis [GO:0006884]; cellular chloride ion homeostasis [GO:0030644]; cellular potassium ion homeostasis [GO:0030007]; cellular response to chemokine [GO:1990869]; cellular response to potassium ion [GO:0035865]; cellular sodium ion homeostasis [GO:0006883]; chloride ion homeostasis [GO:0055064]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid signaling pathway [GO:0007214]; hyperosmotic response [GO:0006972]; inorganic anion import across plasma membrane [GO:0098658]; inorganic cation import across plasma membrane [GO:0098659]; ion transport [GO:0006811]; maintenance of blood-brain barrier [GO:0035633]; negative regulation of vascular wound healing [GO:0061044]; positive regulation of aspartate secretion [GO:1904450]; positive regulation of cell volume [GO:0045795]; potassium ion homeostasis [GO:0055075]; potassium ion import across plasma membrane [GO:1990573]; regulation of matrix metallopeptidase secretion [GO:1904464]; regulation of spontaneous synaptic transmission [GO:0150003]; sodium ion homeostasis [GO:0055078]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725]; T cell chemotaxis [GO:0010818]; transepithelial ammonium transport [GO:0070634]; transepithelial chloride transport [GO:0030321]; transport across blood-brain barrier [GO:0150104] GO:0005829; GO:0005886; GO:0006811; GO:0006883; GO:0006884; GO:0006972; GO:0007214; GO:0007568; GO:0008511; GO:0008519; GO:0009925; GO:0010818; GO:0015079; GO:0015377; GO:0015379; GO:0016020; GO:0016323; GO:0016324; GO:0016328; GO:0019901; GO:0030007; GO:0030321; GO:0030644; GO:0030659; GO:0031253; GO:0035633; GO:0035725; GO:0035865; GO:0042995; GO:0043005; GO:0043025; GO:0044297; GO:0044298; GO:0045795; GO:0046873; GO:0051087; GO:0051879; GO:0055064; GO:0055075; GO:0055078; GO:0061044; GO:0070062; GO:0070634; GO:0071944; GO:0072488; GO:0098658; GO:0098659; GO:0098719; GO:0150003; GO:0150104; GO:1902476; GO:1903561; GO:1904450; GO:1904464; GO:1990573; GO:1990869 47613 XR_006396158.1 81 50 32 39 70 P55011 0 Solute carrier family 12 member 2 (Basolateral Na-K-Cl symporter) (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2) Homo sapiens (Human) aging [GO:0007568]; ammonium transmembrane transport [GO:0072488]; cell volume homeostasis [GO:0006884]; cellular chloride ion homeostasis [GO:0030644]; cellular potassium ion homeostasis [GO:0030007]; cellular response to chemokine [GO:1990869]; cellular response to potassium ion [GO:0035865]; cellular sodium ion homeostasis [GO:0006883]; chloride ion homeostasis [GO:0055064]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid signaling pathway [GO:0007214]; hyperosmotic response [GO:0006972]; inorganic anion import across plasma membrane [GO:0098658]; inorganic cation import across plasma membrane [GO:0098659]; ion transport [GO:0006811]; maintenance of blood-brain barrier [GO:0035633]; negative regulation of vascular wound healing [GO:0061044]; positive regulation of aspartate secretion [GO:1904450]; positive regulation of cell volume [GO:0045795]; potassium ion homeostasis [GO:0055075]; potassium ion import across plasma membrane [GO:1990573]; regulation of matrix metallopeptidase secretion [GO:1904464]; regulation of spontaneous synaptic transmission [GO:0150003]; sodium ion homeostasis [GO:0055078]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725]; T cell chemotaxis [GO:0010818]; transepithelial ammonium transport [GO:0070634]; transepithelial chloride transport [GO:0030321]; transport across blood-brain barrier [GO:0150104] GO:0005829; GO:0005886; GO:0006811; GO:0006883; GO:0006884; GO:0006972; GO:0007214; GO:0007568; GO:0008511; GO:0008519; GO:0009925; GO:0010818; GO:0015079; GO:0015377; GO:0015379; GO:0016020; GO:0016323; GO:0016324; GO:0016328; GO:0019901; GO:0030007; GO:0030321; GO:0030644; GO:0030659; GO:0031253; GO:0035633; GO:0035725; GO:0035865; GO:0042995; GO:0043005; GO:0043025; GO:0044297; GO:0044298; GO:0045795; GO:0046873; GO:0051087; GO:0051879; GO:0055064; GO:0055075; GO:0055078; GO:0061044; GO:0070062; GO:0070634; GO:0071944; GO:0072488; GO:0098658; GO:0098659; GO:0098719; GO:0150003; GO:0150104; GO:1902476; GO:1903561; GO:1904450; GO:1904464; GO:1990573; GO:1990869 47614 XM_044308245.1 140 0 35 364 101 Q8CGZ0 2.49e-31 Calcium homeostasis endoplasmic reticulum protein (SR-related CTD-associated factor 6) Mus musculus (Mouse) cellular calcium ion homeostasis [GO:0006874]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; release of sequestered calcium ion into cytosol [GO:0051209]; RNA processing [GO:0006396] GO:0003723; GO:0005737; GO:0006396; GO:0006874; GO:0008285; GO:0033017; GO:0044325; GO:0048471; GO:0051209; GO:0070886 47615 XM_029341134.2 1163 1005 609 1240 1382 Q7Z3U7 0 Protein MON2 homolog (Protein SF21) Homo sapiens (Human) Golgi to endosome transport [GO:0006895]; protein transport [GO:0015031] GO:0005829; GO:0006895; GO:0015031; GO:0031901; GO:0070062 47616 XM_044329247.1 106 47 70 167 71 Q7TN88 3.3e-69 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 47617 XM_044329247.1 106 47 70 167 71 Q7TN88 1.27e-35 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 47618 XM_029337577.2 3169 1725 1942 2908 2705 Q5REX3 1.17e-112 Zinc finger RNA-binding protein Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0003723; GO:0005634; GO:0005694; GO:0005737; GO:0008270 47619 XM_029337577.2 3169 1725 1942 2908 2705 Q5REX3 3.67e-29 Zinc finger RNA-binding protein Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0003723; GO:0005634; GO:0005694; GO:0005737; GO:0008270 47620 XM_029337577.2 3169 1725 1942 2908 2705 Q5REX3 1.14e-22 Zinc finger RNA-binding protein Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0003723; GO:0005634; GO:0005694; GO:0005737; GO:0008270 47621 XR_006393183.1 36 21 21 83 172 NA NA NA NA NA NA 47622 XM_044317994.1 281 203 163 292 379 Q8BKT8 1.29e-22 HAUS augmin-like complex subunit 7 (26S proteasome-associated UCH37-interacting protein 1) (UCHL5-interacting protein) Mus musculus (Mouse) cell division [GO:0051301]; centrosome cycle [GO:0007098]; spindle assembly [GO:0051225] GO:0005730; GO:0005737; GO:0005813; GO:0005886; GO:0007098; GO:0031996; GO:0051011; GO:0051225; GO:0051301; GO:0070652; GO:1990498 47623 XM_044316163.1 6 1 0 13 5 NA NA NA NA NA NA 47624 XM_029328764.2 1047 810 533 743 849 Q8WY54 2.95e-110 Protein phosphatase 1E (EC 3.1.3.16) (Ca(2+)/calmodulin-dependent protein kinase phosphatase N) (CaMKP-N) (CaMKP-nucleus) (CaMKN) (Partner of PIX 1) (Partner of PIX-alpha) (Partner of PIXA) Homo sapiens (Human) cellular response to xenobiotic stimulus [GO:0071466]; negative regulation of protein kinase activity [GO:0006469]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of stress fiber assembly [GO:0051496]; protein dephosphorylation [GO:0006470] GO:0004722; GO:0005634; GO:0005654; GO:0005730; GO:0005739; GO:0006469; GO:0006470; GO:0017018; GO:0032991; GO:0035970; GO:0046872; GO:0051496; GO:0071466 47625 XM_029349131.2 2839 1939 1662 2405 2370 P98194 0 Calcium-transporting ATPase type 2C member 1 (ATPase 2C1) (EC 7.2.2.10) (ATP-dependent Ca(2+) pump PMR1) (Ca(2+)/Mn(2+)-ATPase 2C1) (Secretory pathway Ca(2+)-transporting ATPase type 1) (SPCA1) Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cellular calcium ion homeostasis [GO:0006874]; cellular manganese ion homeostasis [GO:0030026]; epidermis development [GO:0008544]; Golgi calcium ion homeostasis [GO:0032468]; Golgi calcium ion transport [GO:0032472]; ion transmembrane transport [GO:0034220]; manganese ion transport [GO:0006828]; positive regulation of Golgi to plasma membrane protein transport [GO:0042998]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; trans-Golgi network membrane organization [GO:0098629] GO:0000139; GO:0005388; GO:0005509; GO:0005524; GO:0005783; GO:0005794; GO:0005802; GO:0005886; GO:0006816; GO:0006828; GO:0006874; GO:0008544; GO:0015662; GO:0016020; GO:0016339; GO:0016887; GO:0030026; GO:0030145; GO:0031532; GO:0032468; GO:0032472; GO:0032580; GO:0033106; GO:0034220; GO:0042998; GO:0043123; GO:0046872; GO:0070588; GO:0098629; GO:0140613 47626 XM_029342271.2 528 425 253 1033 807 NA NA NA NA NA NA 47627 XM_029351060.2 746 492 263 632 552 Q6NRK1 1.7e-67 Afadin- and alpha-actinin-binding protein A (ADIP-A) (Afadin DIL domain-interacting protein A) (SSX2-interacting protein A) (XSSX2IP) Xenopus laevis (African clawed frog) cell adhesion [GO:0007155]; centrosome cycle [GO:0007098] GO:0005737; GO:0005874; GO:0005912; GO:0007098; GO:0007155; GO:0034451; GO:0051011 47628 XM_029334393.2 29 8 10 17 151 O35111 6.22e-28 Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (Cardiac two pore background K(+) channel) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1) (Two pore K(+) channel KT3.1) (cTBAK-1) Mus musculus (Mouse) brain development [GO:0007420]; cellular response to hypoxia [GO:0071456]; cellular response to zinc ion [GO:0071294]; cochlea development [GO:0090102]; ion transmembrane transport [GO:0034220]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; positive regulation of voltage-gated potassium channel activity [GO:1903818]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of resting membrane potential [GO:0060075]; response to xenobiotic stimulus [GO:0009410]; stabilization of membrane potential [GO:0030322] GO:0005216; GO:0005252; GO:0005886; GO:0006813; GO:0007420; GO:0008022; GO:0009410; GO:0015271; GO:0022841; GO:0030322; GO:0034220; GO:0044548; GO:0051481; GO:0060075; GO:0071294; GO:0071456; GO:0071805; GO:0090102; GO:1903818 47629 XM_044321900.1 203 101 96 183 382 NA NA NA NA NA NA 47630 XM_044321991.1 9 0 8 0 34 NA NA NA NA NA NA 47631 XM_044317551.1 141 39 137 536 166 NA NA NA NA NA NA 47632 XM_044313885.1 0 0 0 7 0 NA NA NA NA NA NA 47633 XR_006393657.1 11 6 4 6 6 NA NA NA NA NA NA 47634 XM_029345346.2 70 69 55 63 142 NA NA NA NA NA NA 47635 XM_029333594.2 1370 1006 702 646 111 A0JPI9 2.14e-72 Leucine-rich repeat-containing protein 74A (Leucine-rich repeat-containing protein 74) Rattus norvegicus (Rat) NA NA 47636 XM_029331697.2 1458 848 615 1218 1341 Q3YEC7 6.01e-89 Rab-like protein 6 (GTP-binding protein Parf) (Partner of ARF) (Rab-like protein 1) (RBEL1) Homo sapiens (Human) NA GO:0003924; GO:0005525; GO:0005634; GO:0005737; GO:0005813; GO:0005829 47637 XM_029332965.2 1204 1007 705 857 853 Q5ZLD7 0 Vacuolar protein sorting-associated protein 53 homolog Gallus gallus (Chicken) endocytic recycling [GO:0032456]; protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147] GO:0000938; GO:0005829; GO:0010008; GO:0015031; GO:0032456; GO:0042147; GO:0055037; GO:1990745 47638 XM_029337403.2 582 193 449 340 150 P49744 2.13e-179 Thrombospondin-4 Rattus norvegicus (Rat) behavioral response to pain [GO:0048266]; endothelial cell-cell adhesion [GO:0071603]; myoblast migration [GO:0051451]; negative regulation of angiogenesis [GO:0016525]; nervous system development [GO:0007399]; neuron projection morphogenesis [GO:0048812]; positive regulation of cell division [GO:0051781]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of tissue remodeling [GO:0034103]; response to endoplasmic reticulum stress [GO:0034976]; response to unfolded protein [GO:0006986]; tissue remodeling [GO:0048771] GO:0001938; GO:0001968; GO:0005178; GO:0005509; GO:0005518; GO:0005604; GO:0005615; GO:0005783; GO:0006986; GO:0007399; GO:0008083; GO:0008201; GO:0016525; GO:0016529; GO:0031012; GO:0031594; GO:0034103; GO:0034976; GO:0042802; GO:0043237; GO:0048266; GO:0048771; GO:0048812; GO:0050731; GO:0051451; GO:0051781; GO:0062023; GO:0071603; GO:0090023 47639 XM_044322549.1 18 2 0 6 14 P70490 1.46e-31 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 47640 XM_044317740.1 3 0 0 0 9 Q69ZM6 1.44e-164 Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog) Mus musculus (Mouse) axoneme assembly [GO:0035082]; brain development [GO:0007420]; cilium assembly [GO:0060271]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; positive regulation of hh target transcription factor activity [GO:0007228]; positive regulation of smoothened signaling pathway [GO:0045880]; post-embryonic development [GO:0009791]; protein phosphorylation [GO:0006468]; regulation of DNA-binding transcription factor activity [GO:0051090]; smoothened signaling pathway [GO:0007224] GO:0001222; GO:0003351; GO:0004674; GO:0005524; GO:0005576; GO:0005634; GO:0005737; GO:0005829; GO:0005856; GO:0006468; GO:0007224; GO:0007228; GO:0007420; GO:0009791; GO:0035082; GO:0042995; GO:0045880; GO:0046872; GO:0051090; GO:0060271; GO:0106310 47641 XR_006391638.1 25 0 29 9 76 NA NA NA NA NA NA 47642 XM_029333683.2 14 19 3 48 32 NA NA NA NA NA NA 47643 XR_003827075.2 26 18 2 18 17 NA NA NA NA NA NA 47644 XR_003824448.2 27 12 6 12 3 NA NA NA NA NA NA 47645 XM_029344532.2 0 0 57 0 4 Q91Y77 4.02e-38 Monocarboxylate transporter 10 (MCT 10) (Aromatic amino acid transporter 1) (Solute carrier family 16 member 10) (T-type amino acid transporter 1) Rattus norvegicus (Rat) aromatic amino acid transport [GO:0015801]; thyroid hormone generation [GO:0006590]; thyroid hormone transport [GO:0070327]; thyroid-stimulating hormone secretion [GO:0070460] GO:0005302; GO:0005886; GO:0006590; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0070327; GO:0070460 47646 XM_044310982.1 295 163 193 346 378 Q6GNJ8 1.89e-42 Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) Xenopus laevis (African clawed frog) regulation of DNA-templated transcription [GO:0006355]; transcription initiation-coupled chromatin remodeling [GO:0045815] GO:0003677; GO:0005634; GO:0006355; GO:0045815; GO:0140713; GO:0140849 47647 XM_044320193.1 6 0 3 1 8 NA NA NA NA NA NA 47648 XM_044310057.1 0 4 0 91 11 NA NA NA NA NA NA 47649 XM_044318112.1 34 2 16 2 27 NA NA NA NA NA NA 47650 XM_044320177.1 273 32 122 138 217 Q9ULJ7 9.21e-53 Ankyrin repeat domain-containing protein 50 Homo sapiens (Human) endocytic recycling [GO:0032456]; protein transport [GO:0015031] GO:0005768; GO:0015031; GO:0032456 47651 XM_044313087.1 12 107 8 194 141 NA NA NA NA NA NA 47652 XM_044309250.1 26 0 8 1 7 NA NA NA NA NA NA 47653 XM_044317344.1 378 20 116 393 391 Q9Y4E6 0 WD repeat-containing protein 7 (Rabconnectin-3 beta) (TGF-beta resistance-associated protein TRAG) Homo sapiens (Human) hematopoietic progenitor cell differentiation [GO:0002244] GO:0002244; GO:0005737 47654 XM_029346925.2 243 152 138 149 168 Q9D8B1 1.32e-31 Androgen-induced gene 1 protein (AIG-1) (Fatty acid esters of hydroxy fatty acids hydrolase AIG1) (FAHFA hydrolase AIG1) (EC 3.1.-.-) Mus musculus (Mouse) long-chain fatty acid catabolic process [GO:0042758] GO:0005886; GO:0012505; GO:0016020; GO:0016787; GO:0042758 47655 XM_044325536.1 582 356 316 291 449 Q9QYI4 2.77e-85 DnaJ homolog subfamily B member 12 (mDj10) Mus musculus (Mouse) cellular response to misfolded protein [GO:0071218]; chaperone cofactor-dependent protein refolding [GO:0051085]; ERAD pathway [GO:0036503]; protein-containing complex assembly [GO:0065003]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0005783; GO:0005789; GO:0030433; GO:0030544; GO:0031965; GO:0036503; GO:0051085; GO:0065003; GO:0071218 47656 XM_044328325.1 780 33 392 2704 1970 NA NA NA NA NA NA 47657 XM_029355434.2 1148 1152 837 727 773 A3KP37 7.45e-128 Arginine-hydroxylase NDUFAF5, mitochondrial (EC 1.-.-.-) (NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5) (Putative methyltransferase NDUFAF5) (EC 2.1.1.-) Danio rerio (Zebrafish) (Brachydanio rerio) methylation [GO:0032259]; mitochondrial respiratory chain complex I assembly [GO:0032981]; peptidyl-arginine hydroxylation [GO:0030961] GO:0005739; GO:0005743; GO:0008168; GO:0016491; GO:0030961; GO:0032259; GO:0032981 47658 XM_044309524.1 0 0 0 27 33 P35556 8.31e-28 Fibrillin-2 [Cleaved into: Placensin] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030023; GO:0030326; GO:0030501; GO:0031012; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 47659 XM_044309524.1 0 0 0 27 33 P35556 6.19e-25 Fibrillin-2 [Cleaved into: Placensin] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030023; GO:0030326; GO:0030501; GO:0031012; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 47660 XM_044309524.1 0 0 0 27 33 P35556 8.83e-24 Fibrillin-2 [Cleaved into: Placensin] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030023; GO:0030326; GO:0030501; GO:0031012; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 47661 XM_044313355.1 787 79 55 1799 212 Q9HCK4 2.14e-25 Roundabout homolog 2 Homo sapiens (Human) aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; apoptotic process involved in luteolysis [GO:0061364]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; brain development [GO:0007420]; cell-cell adhesion [GO:0098609]; cellular response to hormone stimulus [GO:0032870]; central nervous system development [GO:0007417]; endocardial cushion formation [GO:0003272]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; metanephros development [GO:0001656]; negative regulation of negative chemotaxis [GO:0050925]; negative regulation of synapse assembly [GO:0051964]; olfactory bulb interneuron development [GO:0021891]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; pulmonary valve morphogenesis [GO:0003184]; retinal ganglion cell axon guidance [GO:0031290]; ureteric bud development [GO:0001657]; ventricular septum morphogenesis [GO:0060412] GO:0001656; GO:0001657; GO:0003148; GO:0003180; GO:0003184; GO:0003272; GO:0005886; GO:0007156; GO:0007411; GO:0007417; GO:0007420; GO:0008046; GO:0009986; GO:0016199; GO:0021891; GO:0030424; GO:0030673; GO:0031290; GO:0032870; GO:0035481; GO:0035904; GO:0042802; GO:0050772; GO:0050925; GO:0051964; GO:0060412; GO:0061364; GO:0070062; GO:0098609; GO:0098632 47662 XR_003828614.2 203 130 199 124 18 NA NA NA NA NA NA 47663 XM_044318410.1 11 0 0 0 1 NA NA NA NA NA NA 47664 XM_044322042.1 10 24 0 19 9 Q9CZJ1 3.67e-46 Probable U3 small nucleolar RNA-associated protein 11 (U3 snoRNA-associated protein 11) (UTP11-like protein) Mus musculus (Mouse) nervous system development [GO:0007399]; positive regulation of apoptotic process [GO:0043065]; rRNA processing [GO:0006364] GO:0005615; GO:0005730; GO:0005737; GO:0006364; GO:0007399; GO:0032040; GO:0043065 47665 XM_044328089.1 574 269 309 952 600 Q6NZF1 2.4e-29 Zinc finger CCCH domain-containing protein 11A Mus musculus (Mouse) poly(A)+ mRNA export from nucleus [GO:0016973] GO:0000346; GO:0003729; GO:0016973; GO:0046872 47666 XR_006395773.1 19 40 68 11 107 NA NA NA NA NA NA 47667 XM_029358451.2 99 66 2 35 39 NA NA NA NA NA NA 47668 XM_029347187.2 2672 4343 1863 2739 1348 P51128 3.87e-66 Retinoic acid receptor RXR-alpha (Nuclear receptor subfamily 2 group B member 1) (Retinoid X receptor alpha) Xenopus laevis (African clawed frog) NA GO:0003700; GO:0003707; GO:0005634; GO:0008270; GO:0043565; GO:0046966; GO:0046982 47669 XM_029356082.2 1458 1825 1207 1370 1129 Q8NB59 1.94e-23 Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV) Homo sapiens (Human) NA GO:0005543; GO:0016020 47670 XM_044322037.1 282 420 233 535 664 Q5RKQ0 3.92e-89 Pre-mRNA-splicing factor SPF27 (Protein BCAS2 homolog) Danio rerio (Zebrafish) (Brachydanio rerio) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0000974; GO:0005634; GO:0071007; GO:0071013 47671 XR_006394314.1 52 108 0 125 371 NA NA NA NA NA NA 47672 XM_044325588.1 34 4 23 31 46 NA NA NA NA NA NA 47673 XM_029339445.2 11 36 30 12 41 P57101 5.02e-30 Heart- and neural crest derivatives-expressed protein 2 (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND) Xenopus laevis (African clawed frog) NA GO:0003677; GO:0005634; GO:0046983 47674 XR_003825184.2 18 70 16 38 34 NA NA NA NA NA NA 47675 XM_029331141.2 312 523 210 258 136 Q61382 2.86e-61 TNF receptor-associated factor 4 (EC 2.3.2.27) (Cysteine-rich motif associated to RING and Traf domains protein 1) Mus musculus (Mouse) activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; innate immune response [GO:0045087]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein kinase activity [GO:0045860]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; respiratory gaseous exchange by respiratory system [GO:0007585]; respiratory tube development [GO:0030323] GO:0001650; GO:0005164; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0005923; GO:0006915; GO:0007250; GO:0007585; GO:0008270; GO:0016740; GO:0019901; GO:0030323; GO:0031625; GO:0031996; GO:0042802; GO:0042981; GO:0043122; GO:0043161; GO:0045087; GO:0045860; GO:0046330; GO:0048471; GO:0050699 47676 XM_044320318.1 71 0 0 0 168 Q14CM0 1.56e-76 FERM and PDZ domain-containing protein 4 (PDZ domain-containing protein 10) (PSD-95-interacting regulator of spine morphogenesis) (Preso) Homo sapiens (Human) positive regulation of synapse structural plasticity [GO:0051835] GO:0005546; GO:0005856; GO:0032991; GO:0043197; GO:0051835 47677 XM_044318966.1 5 0 4 2105 1323 Q17005 6.4e-28 Lysozyme c-1 (EC 3.2.1.17) (1,4-beta-N-acetylmuramidase) Anopheles gambiae (African malaria mosquito) cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152] GO:0003796; GO:0008152; GO:0019835; GO:0042742 47678 XM_029342220.2 0 47 0 0 54 NA NA NA NA NA NA 47679 XM_044324524.1 139 0 46 33 0 A7MBP4 1.56e-120 Intraflagellar transport protein 46 homolog Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; determination of ventral identity [GO:0048264]; intraciliary transport [GO:0042073]; pronephros development [GO:0048793]; retina development in camera-type eye [GO:0060041] GO:0005737; GO:0005813; GO:0030992; GO:0031514; GO:0036064; GO:0042073; GO:0048264; GO:0048793; GO:0060041; GO:0060271 47680 XM_029340986.2 388 87 75 0 0 Q8K078 7.45e-119 Solute carrier organic anion transporter family member 4A1 (Organic anion-transporting polypeptide E) (OATP-E) (Sodium-independent organic anion transporter E) (Solute carrier family 21 member 12) Mus musculus (Mouse) sodium-independent organic anion transport [GO:0043252]; thyroid hormone metabolic process [GO:0042403] GO:0005886; GO:0008514; GO:0015132; GO:0015347; GO:0015349; GO:0042403; GO:0043252 47681 XM_029351158.2 377 110 251 482 573 D3YXG0 0 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 47682 XM_029351158.2 377 110 251 482 573 D3YXG0 0 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 47683 XM_029351158.2 377 110 251 482 573 D3YXG0 0 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 47684 XM_029351158.2 377 110 251 482 573 D3YXG0 0 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 47685 XM_029351158.2 377 110 251 482 573 D3YXG0 4.5e-158 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 47686 XM_029334673.2 15 17 31 31 57 NA NA NA NA NA NA 47687 XM_044323920.1 511 323 208 275 294 NA NA NA NA NA NA 47688 XM_044323239.1 1007 651 527 593 892 O54941 4.25e-71 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 (BRG1-associated factor 57) (BAF57) Mus musculus (Mouse) chromatin remodeling [GO:0006338]; negative regulation of DNA-templated transcription [GO:0045892]; neurogenesis [GO:0022008]; nucleosome disassembly [GO:0006337]; positive regulation of cell differentiation [GO:0045597]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of T cell differentiation [GO:0045582]; regulation of G0 to G1 transition [GO:0070316]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of nucleotide-excision repair [GO:2000819]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000776; GO:0000785; GO:0003677; GO:0003723; GO:0005634; GO:0005654; GO:0006337; GO:0006338; GO:0006357; GO:0008080; GO:0016363; GO:0016514; GO:0016586; GO:0016922; GO:0022008; GO:0030071; GO:0035060; GO:0045582; GO:0045597; GO:0045663; GO:0045892; GO:0047485; GO:0070316; GO:0071564; GO:0071565; GO:0140092; GO:1902459; GO:2000045; GO:2000781; GO:2000819 47689 XM_044307715.1 15 127 0 19 41 Q9WTS8 1.13e-63 Ficolin-1 (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin-alpha) (M-ficolin) Rattus norvegicus (Rat) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to virus [GO:0051607]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of RNA biosynthetic process [GO:1902679]; negative regulation of viral entry into host cell [GO:0046597]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of opsonization [GO:1903028]; proteolysis [GO:0006508]; recognition of apoptotic cell [GO:0043654] GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005581; GO:0005615; GO:0006508; GO:0006956; GO:0007186; GO:0030246; GO:0031232; GO:0032757; GO:0038187; GO:0043654; GO:0046597; GO:0046872; GO:0051607; GO:0062023; GO:0097367; GO:1902679; GO:1903028; GO:1905370 47690 XR_003825266.2 6 10 42 1 33 NA NA NA NA NA NA 47691 XM_044321293.1 345 126 0 59 146 Q13416 3.77e-112 Origin recognition complex subunit 2 Homo sapiens (Human) DNA replication initiation [GO:0006270]; negative regulation of transcription by RNA polymerase II [GO:0000122] GO:0000122; GO:0000781; GO:0000792; GO:0000808; GO:0000939; GO:0003688; GO:0005634; GO:0005654; GO:0005664; GO:0005813; GO:0006270; GO:0016020 47692 XM_044323071.1 54 0 0 140 115 P10665 1.26e-25 Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (p90-RSK) Xenopus laevis (African clawed frog) intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468] GO:0000287; GO:0004674; GO:0005524; GO:0006468; GO:0035556; GO:0106310 47693 XM_044312745.1 0 0 0 0 20 Q8IZU8 4.27e-180 Dermatan-sulfate epimerase-like protein (EC 5.1.-.-) Homo sapiens (Human) chondroitin sulfate metabolic process [GO:0030204]; dermatan sulfate biosynthetic process [GO:0030208]; dermatan sulfate metabolic process [GO:0030205] GO:0000139; GO:0008146; GO:0030204; GO:0030205; GO:0030208; GO:0047757 47694 XM_029335693.2 0 0 1 7 0 NA NA NA NA NA NA 47695 XM_029337285.2 1416 638 819 1468 1638 Q5SSH7 0 Zinc finger ZZ-type and EF-hand domain-containing protein 1 Mus musculus (Mouse) neuroblast proliferation [GO:0007405]; protein ubiquitination [GO:0016567]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]; visual learning [GO:0008542] GO:0005509; GO:0007405; GO:0008270; GO:0008542; GO:0009986; GO:0016567; GO:0035064; GO:0035249; GO:0045202; GO:0048167; GO:0048786; GO:0050730; GO:0061659; GO:0070577; GO:0098794; GO:0140566 47696 XM_029337285.2 1416 638 819 1468 1638 Q5SSH7 3.42e-113 Zinc finger ZZ-type and EF-hand domain-containing protein 1 Mus musculus (Mouse) neuroblast proliferation [GO:0007405]; protein ubiquitination [GO:0016567]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]; visual learning [GO:0008542] GO:0005509; GO:0007405; GO:0008270; GO:0008542; GO:0009986; GO:0016567; GO:0035064; GO:0035249; GO:0045202; GO:0048167; GO:0048786; GO:0050730; GO:0061659; GO:0070577; GO:0098794; GO:0140566 47697 XM_029337285.2 1416 638 819 1468 1638 Q5SSH7 4.85e-69 Zinc finger ZZ-type and EF-hand domain-containing protein 1 Mus musculus (Mouse) neuroblast proliferation [GO:0007405]; protein ubiquitination [GO:0016567]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]; visual learning [GO:0008542] GO:0005509; GO:0007405; GO:0008270; GO:0008542; GO:0009986; GO:0016567; GO:0035064; GO:0035249; GO:0045202; GO:0048167; GO:0048786; GO:0050730; GO:0061659; GO:0070577; GO:0098794; GO:0140566 47698 XM_029344859.2 3557 1550 1765 1419 1206 NA NA NA NA NA NA 47699 XM_044313868.1 28 47 7 110 92 NA NA NA NA NA NA 47700 XM_044322172.1 31 112 29 97 46 NA NA NA NA NA NA 47701 XM_044317211.1 266 137 128 344 369 NA NA NA NA NA NA 47702 XM_044327266.1 25 38 0 1 5 NA NA NA NA NA NA 47703 XM_044321510.1 87 66 70 44 91 Q9TSL6 3.72e-60 UDP-glucuronosyltransferase 2B23 (UDPGT 2B23) (EC 2.4.1.17) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0005789; GO:0015020 47704 XR_006394824.1 50 17 21 25 217 NA NA NA NA NA NA 47705 XM_044310906.1 12 0 0 0 59 NA NA NA NA NA NA 47706 XM_044327542.1 0 10 0 14 121 P10894 0 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (EC 3.1.4.11) (PLC-154) (Phosphoinositide phospholipase C-beta-1) (Phospholipase C-beta-1) (PLC-beta-1) Bos taurus (Bovine) interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-15-mediated signaling pathway [GO:0035723]; lipid catabolic process [GO:0016042]; memory [GO:0007613]; phosphatidylinositol metabolic process [GO:0046488]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of JNK cascade [GO:0046330] GO:0004435; GO:0005096; GO:0005509; GO:0005516; GO:0005546; GO:0005737; GO:0005829; GO:0007613; GO:0016042; GO:0016607; GO:0019899; GO:0031965; GO:0035722; GO:0035723; GO:0046330; GO:0046488; GO:0048015; GO:0070498 47707 XM_044326818.1 0 0 3 8 17 NA NA NA NA NA NA 47708 XM_044310376.1 68 15 32 25 29 NA NA NA NA NA NA 47709 XM_029356827.2 0 0 3 0 137 NA NA NA NA NA NA 47710 XM_029339112.2 620 291 163 190 106 Q3TZ87 1.2e-22 E3 ubiquitin-protein ligase MARCHF9 (EC 2.3.2.27) (Membrane-associated RING finger protein 9) (Membrane-associated RING-CH protein IX) (MARCH-IX) (RING-type E3 ubiquitin transferase MARCHF9) Mus musculus (Mouse) NA GO:0000139; GO:0004842; GO:0005765; GO:0005795; GO:0005802; GO:0008270 47711 XM_044327077.1 716 584 0 332 13 Q9BXW9 0 Fanconi anemia group D2 protein (Protein FACD2) Homo sapiens (Human) brain morphogenesis [GO:0048854]; cellular response to oxidative stress [GO:0034599]; double-strand break repair involved in meiotic recombination [GO:1990918]; gamete generation [GO:0007276]; homologous chromosome pairing at meiosis [GO:0007129]; interstrand cross-link repair [GO:0036297]; mitotic intra-S DNA damage checkpoint signaling [GO:0031573]; neuronal stem cell population maintenance [GO:0097150]; regulation of CD40 signaling pathway [GO:2000348]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of inflammatory response [GO:0050727]; regulation of regulatory T cell differentiation [GO:0045589]; response to gamma radiation [GO:0010332] GO:0000785; GO:0000793; GO:0005634; GO:0005654; GO:0005730; GO:0005829; GO:0007129; GO:0007276; GO:0010332; GO:0016604; GO:0031573; GO:0034599; GO:0036297; GO:0045589; GO:0048854; GO:0050727; GO:0051090; GO:0070182; GO:0097150; GO:1990391; GO:1990918; GO:2000348 47712 XM_044316858.1 1911 2352 1384 4171 4313 P18899 3.41e-21 Stress protein DDR48 (DNA damage-responsive protein 48) (DDRP 48) (Flocculent-specific protein) (YP 75) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA repair [GO:0006281] GO:0003924; GO:0005737; GO:0005829; GO:0006281; GO:0016887 47713 XM_044326447.1 624 695 368 870 550 Q8R164 2.82e-104 Valacyclovir hydrolase (VACVase) (Valacyclovirase) (EC 3.1.-.-) (Biphenyl hydrolase-like protein) Mus musculus (Mouse) NA GO:0005739; GO:0047658 47714 XM_044322450.1 109 105 76 163 27 Q13003 8.69e-85 Glutamate receptor ionotropic, kainate 3 (GluK3) (Excitatory amino acid receptor 5) (EAA5) (Glutamate receptor 7) (GluR-7) (GluR7) Homo sapiens (Human) G protein-coupled glutamate receptor signaling pathway [GO:0007216]; glutamate receptor signaling pathway [GO:0007215]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; regulation of membrane potential [GO:0042391]; synaptic transmission, glutamatergic [GO:0035249] GO:0001640; GO:0004970; GO:0005886; GO:0007215; GO:0007216; GO:0008066; GO:0015276; GO:0015277; GO:0030424; GO:0030425; GO:0032839; GO:0032983; GO:0035249; GO:0038023; GO:0042391; GO:0042734; GO:0043195; GO:0043204; GO:0045211; GO:0050804; GO:0051967; GO:0098978; GO:0099507; GO:1904315 47715 XM_029324745.2 89 21 155 61 177 Q9H0Z9 1.6e-31 RNA-binding protein 38 (CLL-associated antigen KW-5) (HSRNASEB) (RNA-binding motif protein 38) (RNA-binding region-containing protein 1) (ssDNA-binding protein SEB4) Homo sapiens (Human) 3'-UTR-mediated mRNA stabilization [GO:0070935]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; mRNA processing [GO:0006397]; mRNA stabilization [GO:0048255]; negative regulation of cell population proliferation [GO:0008285]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of cell cycle [GO:0051726]; regulation of myotube differentiation [GO:0010830]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380] GO:0000381; GO:0003723; GO:0003729; GO:0003730; GO:0005634; GO:0005829; GO:0006397; GO:0006977; GO:0006978; GO:0007049; GO:0008285; GO:0008380; GO:0010830; GO:0030154; GO:0043484; GO:0048255; GO:0051726; GO:0070935 47716 XR_006394869.1 0 0 19 4 194 NA NA NA NA NA NA 47717 XM_044327861.1 460 387 37 468 932 P10079 0 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 47718 XM_044327861.1 460 387 37 468 932 P10079 0 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 47719 XM_044327861.1 460 387 37 468 932 P10079 0 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 47720 XM_044327861.1 460 387 37 468 932 P10079 0 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 47721 XM_044327861.1 460 387 37 468 932 P10079 0 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 47722 XM_044327861.1 460 387 37 468 932 P10079 3.99e-101 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 47723 XM_029356701.2 117 0 176 285 284 Q6P2S7 3.86e-111 Putative tetratricopeptide repeat protein 41 (TPR repeat protein 41) (Grp94-neighboring nucleotidase) Homo sapiens (Human) NA GO:0005737 47724 XM_044312917.1 381 317 254 303 176 NA NA NA NA NA NA 47725 XM_044321575.1 268 127 603 205 424 NA NA NA NA NA NA 47726 XM_029325189.2 124 14 20 61 24 NA NA NA NA NA NA 47727 XM_044309228.1 57 32 19 26 1259 NA NA NA NA NA NA 47728 XM_044325478.1 0 0 34 23 35 Q80SY4 1.53e-49 E3 ubiquitin-protein ligase MIB1 (EC 2.3.2.27) (DAPK-interacting protein 1) (DIP-1) (Mind bomb homolog 1) (RING-type E3 ubiquitin transferase MIB1) Mus musculus (Mouse) blood vessel development [GO:0001568]; endocytosis [GO:0006897]; heart development [GO:0007507]; heart looping [GO:0001947]; in utero embryonic development [GO:0001701]; negative regulation of neuron differentiation [GO:0045665]; neural tube formation [GO:0001841]; neuron differentiation [GO:0030182]; Notch signaling pathway [GO:0007219]; positive regulation of endocytosis [GO:0045807]; protein ubiquitination [GO:0016567]; somitogenesis [GO:0001756]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0001568; GO:0001701; GO:0001756; GO:0001841; GO:0001947; GO:0004842; GO:0005737; GO:0005813; GO:0005886; GO:0006511; GO:0006897; GO:0007219; GO:0007507; GO:0008270; GO:0014069; GO:0016567; GO:0030182; GO:0031410; GO:0045665; GO:0045807 47729 XM_029330972.2 78 78 77 140 283 P70426 1e-33 GTP-binding protein Rit1 (EC 3.6.5.2) (Ras-like protein expressed in many tissues) (Ras-like without CAAX protein 1) Mus musculus (Mouse) Ras protein signal transduction [GO:0007265] GO:0003924; GO:0003925; GO:0005516; GO:0005525; GO:0005886; GO:0007265; GO:0019003 47730 XM_029339409.2 145 126 187 433 635 NA NA NA NA NA NA 47731 XM_029351409.2 919 419 302 886 778 P97521 2.47e-93 Mitochondrial carnitine/acylcarnitine carrier protein (Carnitine/acylcarnitine translocase) (CAC) (CACT) (Solute carrier family 25 member 20) Rattus norvegicus (Rat) carnitine transmembrane transport [GO:1902603]; in utero embryonic development [GO:0001701]; lipid transport [GO:0006869]; mitochondrial transport [GO:0006839] GO:0001701; GO:0005740; GO:0005743; GO:0006839; GO:0006869; GO:0015227; GO:0022857; GO:1902603 47732 XM_029349627.2 139 152 30 0 0 A2AP18 0 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-eta-2) (Phosphoinositide phospholipase C-like 4) (PLC-L4) (Phospholipase C-like protein 4) (Phospholipase C-eta-2) (PLC-eta2) Mus musculus (Mouse) lipid catabolic process [GO:0016042]; phosphatidylinositol metabolic process [GO:0046488]; phosphatidylinositol-mediated signaling [GO:0048015] GO:0004435; GO:0004629; GO:0005509; GO:0005737; GO:0005886; GO:0016042; GO:0046488; GO:0048015 47733 XM_044327610.1 10 40 26 9 16 NA NA NA NA NA NA 47734 XM_029334624.2 986 504 379 781 717 Q9DC11 3.63e-53 Plexin domain-containing protein 2 (Tumor endothelial marker 7-related protein) Mus musculus (Mouse) NA GO:0005886; GO:0062023 47735 XM_044325179.1 7 8 0 2 13 NA NA NA NA NA NA 47736 XR_003828257.2 61 22 93 20 207 NA NA NA NA NA NA 47737 XM_029345971.2 8 0 0 3 6 NA NA NA NA NA NA 47738 XM_029329807.2 71 0 0 0 0 Q6AYM1 7.3e-27 Uncharacterized protein C5orf34 homolog Rattus norvegicus (Rat) NA NA 47739 XM_029337583.2 309 80 24 208 78 Q9BT88 6.14e-42 Synaptotagmin-11 (Synaptotagmin XI) (SytXI) Homo sapiens (Human) autophagy [GO:0006914]; calcium ion regulated lysosome exocytosis [GO:1990927]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; establishment of vesicle localization [GO:0051650]; learning [GO:0007612]; memory [GO:0007613]; negative regulation of cytokine production [GO:0001818]; negative regulation of dopamine secretion [GO:0033602]; negative regulation of endocytosis [GO:0045806]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of microglial cell activation [GO:1903979]; negative regulation of neurotransmitter secretion [GO:0046929]; negative regulation of phagocytosis [GO:0050765]; negative regulation of tumor necrosis factor production [GO:0032720]; plasma membrane repair [GO:0001778]; positive regulation of protein localization to phagocytic vesicle [GO:1905171]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of defense response to bacterium [GO:1900424]; regulation of dopamine secretion [GO:0014059]; regulation of phagosome maturation [GO:1905162]; regulation of synaptic vesicle endocytosis [GO:1900242]; vesicle fusion [GO:0006906]; vesicle-mediated transport [GO:0016192] GO:0000149; GO:0001778; GO:0001786; GO:0001818; GO:0001891; GO:0005509; GO:0005544; GO:0005764; GO:0005765; GO:0005802; GO:0005886; GO:0006906; GO:0006914; GO:0007612; GO:0007613; GO:0008021; GO:0014059; GO:0014069; GO:0016192; GO:0017156; GO:0017158; GO:0030276; GO:0030424; GO:0030425; GO:0030665; GO:0031369; GO:0031625; GO:0031982; GO:0032009; GO:0032715; GO:0032720; GO:0033602; GO:0042802; GO:0043005; GO:0043197; GO:0043204; GO:0045202; GO:0045335; GO:0045806; GO:0046929; GO:0048487; GO:0048787; GO:0050765; GO:0051650; GO:0055037; GO:0055038; GO:0060076; GO:0060077; GO:0070382; GO:0071277; GO:0098691; GO:0098793; GO:1900242; GO:1900424; GO:1903979; GO:1905162; GO:1905171; GO:1990927 47740 XR_006393352.1 28 2 9 0 38 NA NA NA NA NA NA 47741 XR_006393916.1 41 2 25 5 151 NA NA NA NA NA NA 47742 XM_044324924.1 825 659 411 558 932 Q80ZX8 6.39e-101 Sperm-associated antigen 1 (Infertility-related sperm protein Spag-1) (TPR-containing protein involved in spermatogenesis) (TPIS) Mus musculus (Mouse) axonemal dynein complex assembly [GO:0070286]; single fertilization [GO:0007338] GO:0005525; GO:0005737; GO:0005829; GO:0007338; GO:0016787; GO:0070286; GO:0101031; GO:0120293 47743 XM_029338596.2 291 295 168 220 477 NA NA NA NA NA NA 47744 XM_029331153.2 221 157 39 365 375 O74549 5.86e-21 NEDD8-conjugating enzyme ubc12 (EC 2.3.2.34) (RUB1-conjugating enzyme) (Ubiquitin carrier protein 12) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) protein neddylation [GO:0045116] GO:0005524; GO:0005634; GO:0005829; GO:0019788; GO:0045116; GO:0061654 47745 XM_029340376.2 66 38 46 40 305 NA NA NA NA NA NA 47746 XM_029330636.2 0 842 459 0 615 NA NA NA NA NA NA 47747 XM_044327162.1 435 136 264 328 803 Q5VW36 0 Focadhesin Homo sapiens (Human) regulation of post-transcriptional gene silencing [GO:0060147] GO:0005925; GO:0016020; GO:0060147 47748 XM_029335816.2 891 699 372 649 549 Q05B83 0 Replication factor C subunit 2 (Activator 1 subunit 2) Bos taurus (Bovine) DNA repair [GO:0006281]; DNA-templated DNA replication [GO:0006261]; positive regulation of DNA-directed DNA polymerase activity [GO:1900264] GO:0003677; GO:0003689; GO:0005524; GO:0005634; GO:0005663; GO:0006261; GO:0006281; GO:0016887; GO:0017116; GO:0019899; GO:0031390; GO:1900264 47749 XM_029336072.2 4861 3306 2213 4670 4214 Q9UQB3 1.94e-135 Catenin delta-2 (Delta-catenin) (GT24) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) Homo sapiens (Human) cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-cell junction assembly [GO:0007043]; dendritic spine morphogenesis [GO:0060997]; regulation of canonical Wnt signaling pathway [GO:0060828]; signal transduction [GO:0007165]; synapse organization [GO:0050808]; Wnt signaling pathway [GO:0016055] GO:0005634; GO:0005737; GO:0005886; GO:0005912; GO:0007043; GO:0007155; GO:0007165; GO:0008013; GO:0014069; GO:0016055; GO:0030425; GO:0043204; GO:0045296; GO:0050808; GO:0060828; GO:0060997; GO:0098609 47750 XM_029338099.2 90 35 84 170 112 NA NA NA NA NA NA 47751 XM_044312218.1 10 0 41 19 137 NA NA NA NA NA NA 47752 XR_006397954.1 0 0 2 6 6 NA NA NA NA NA NA 47753 XM_044328961.1 14 11 12 13 25 NA NA NA NA NA NA 47754 XM_044308590.1 14 21 76 35 21 NA NA NA NA NA NA 47755 XM_029336639.2 2415 156 462 1047 358 O88576 0 Sodium-dependent neutral amino acid transporter B(0)AT3 (Sodium- and chloride-dependent transporter XTRP2) (Solute carrier family 6 member 18) (System B(0) neutral amino acid transporter AT3) Mus musculus (Mouse) amino acid transmembrane transport [GO:0003333]; neurotransmitter transport [GO:0006836]; neutral amino acid transport [GO:0015804]; renal amino acid absorption [GO:1990297]; sodium ion transmembrane transport [GO:0035725] GO:0003333; GO:0005886; GO:0006836; GO:0015175; GO:0015804; GO:0016324; GO:0031526; GO:0035725; GO:0140931; GO:1990297 47756 XM_029343923.2 273 182 127 167 110 Q3TZX8 1.56e-72 Polynucleotide 5'-hydroxyl-kinase NOL9 (EC 2.7.1.-) (Nucleolar protein 9) Mus musculus (Mouse) cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000448]; maturation of 5.8S rRNA [GO:0000460]; phosphorylation [GO:0016310]; RNA processing [GO:0006396] GO:0000448; GO:0000460; GO:0003723; GO:0005524; GO:0005634; GO:0005730; GO:0006396; GO:0016310; GO:0045111; GO:0051731 47757 XR_006393438.1 0 0 6 6 0 Q9HAV4 1.7e-36 Exportin-5 (Exp5) (Ran-binding protein 21) Homo sapiens (Human) miRNA metabolic process [GO:0010586]; positive regulation of post-transcriptional gene silencing by RNA [GO:1900370]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; RNA export from nucleus [GO:0006405] GO:0000049; GO:0003723; GO:0003729; GO:0005049; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006405; GO:0006611; GO:0010586; GO:0016442; GO:0031267; GO:0035281; GO:0042565; GO:0070883; GO:1900370; GO:1905172 47758 XM_044321352.1 8 0 1 1001 718 Q96PY6 1.19e-145 Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase 1) (NimA-related protein kinase 1) (Renal carcinoma antigen NY-REN-55) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; cilium assembly [GO:0060271]; protein phosphorylation [GO:0006468] GO:0000242; GO:0004672; GO:0004674; GO:0004713; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0005829; GO:0006468; GO:0007049; GO:0016301; GO:0034451; GO:0046872; GO:0051301; GO:0060271; GO:0071889; GO:0106310 47759 XR_003824961.2 38 0 16 11 67 NA NA NA NA NA NA 47760 XM_044327354.1 16 0 6 0 4 NA NA NA NA NA NA 47761 XM_029337487.2 188 104 79 273 220 NA NA NA NA NA NA 47762 XR_006397519.1 0 1 0 134 0 NA NA NA NA NA NA 47763 XM_044308919.1 31 48 18 37 14 NA NA NA NA NA NA 47764 XR_006396921.1 19 11 28 18 39 NA NA NA NA NA NA 47765 XR_006393695.1 187 83 74 57 59 NA NA NA NA NA NA 47766 XM_044314429.1 169 65 44 82 26 NA NA NA NA NA NA 47767 XR_006393765.1 2 7 2 9 4 NA NA NA NA NA NA 47768 XM_044317852.1 13 0 17 6 41 Q9CUU3 1.12e-27 Synaptonemal complex protein 2 (SCP-2) (Synaptonemal complex lateral element protein) Mus musculus (Mouse) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; cell division [GO:0051301]; ectopic germ cell programmed cell death [GO:0035234]; female meiotic nuclear division [GO:0007143]; fertilization [GO:0009566]; male genitalia morphogenesis [GO:0048808]; male meiotic nuclear division [GO:0007140]; meiotic nuclear division [GO:0140013]; negative regulation of apoptotic process [GO:0043066]; negative regulation of developmental process [GO:0051093]; negative regulation of reproductive process [GO:2000242] GO:0000795; GO:0000800; GO:0003677; GO:0005634; GO:0005654; GO:0006915; GO:0007140; GO:0007143; GO:0009566; GO:0009887; GO:0035234; GO:0043066; GO:0048808; GO:0051093; GO:0051301; GO:0140013; GO:2000242 47769 XR_003824869.2 13636 21097 13281 26119 9823 Q568W0 2.7e-27 Selenoprotein W (SelW) Danio rerio (Zebrafish) (Brachydanio rerio) response to selenium ion [GO:0010269] GO:0005829; GO:0010269; GO:0016209 47770 XR_006391838.1 14 15 15 16 5 NA NA NA NA NA NA 47771 XM_029329968.2 85 11 73 41 34 Q9NQX0 4.97e-76 Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.361) (PR domain zinc finger protein 6) (PR domain-containing protein 6) Homo sapiens (Human) chromatin organization [GO:0006325]; histone methylation [GO:0016571]; negative regulation of smooth muscle cell differentiation [GO:0051151]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of gene expression [GO:0010468] GO:0000122; GO:0005634; GO:0006325; GO:0010468; GO:0016571; GO:0022008; GO:0042802; GO:0046872; GO:0051151; GO:0140944 47772 XM_044327676.1 328 132 127 207 270 NA NA NA NA NA NA 47773 XM_029326545.2 1638 2258 1185 1461 1047 Q0DAE4 7e-25 Glutaredoxin-C8 (Glutaredoxin-C4 homolog) Oryza sativa subsp. japonica (Rice) cellular response to oxidative stress [GO:0034599] GO:0005737; GO:0015038; GO:0034599 47774 XM_029340836.2 92 45 45 60 50 Q864U6 3.04e-31 UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1 (Beta-1,3-GalNAc-T1) (EC 2.4.1.79) (Beta-1,3-galactosyltransferase 3) (Beta-1,3-GalTase 3) (Beta3Gal-T3) (Beta3GalT3) (b3Gal-T3) (Beta-3-Gx-T3) (Galactosylgalactosylglucosylceramide beta-D-acetyl-galactosaminyltransferase) (Globoside synthase) (UDP-N-acetylgalactosamine:globotriaosylceramide beta-1,3-N-acetylgalactosaminyltransferase) Sus scrofa (Pig) lipid metabolic process [GO:0006629]; oligosaccharide biosynthetic process [GO:0009312]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0006629; GO:0008194; GO:0008499; GO:0009312; GO:0016757; GO:0047273 47775 XM_029339927.2 0 500 0 811 1053 Q5T5Y3 1.86e-48 Calmodulin-regulated spectrin-associated protein 1 Homo sapiens (Human) cytoplasmic microtubule organization [GO:0031122]; cytoskeleton organization [GO:0007010]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of microtubule depolymerization [GO:0007026]; neuron projection development [GO:0031175]; regulation of cell morphogenesis [GO:0022604]; regulation of microtubule polymerization [GO:0031113] GO:0000226; GO:0005516; GO:0005737; GO:0005874; GO:0007010; GO:0007026; GO:0008017; GO:0022604; GO:0030507; GO:0031113; GO:0031122; GO:0031175; GO:0051011 47776 XM_029339927.2 0 500 0 811 1053 Q5T5Y3 2.54e-32 Calmodulin-regulated spectrin-associated protein 1 Homo sapiens (Human) cytoplasmic microtubule organization [GO:0031122]; cytoskeleton organization [GO:0007010]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of microtubule depolymerization [GO:0007026]; neuron projection development [GO:0031175]; regulation of cell morphogenesis [GO:0022604]; regulation of microtubule polymerization [GO:0031113] GO:0000226; GO:0005516; GO:0005737; GO:0005874; GO:0007010; GO:0007026; GO:0008017; GO:0022604; GO:0030507; GO:0031113; GO:0031122; GO:0031175; GO:0051011 47777 XM_029350431.2 1502 1105 1005 1408 1043 A0A2K5V015 2.36e-93 Protein eyes shut homolog (Epidermal growth factor-like protein 10) (EGF-like protein 10) (Epidermal growth factor-like protein 11) (EGF-like protein 11) (Protein spacemaker homolog) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) response to stimulus [GO:0050896]; visual perception [GO:0007601] GO:0001750; GO:0005509; GO:0005576; GO:0005737; GO:0005815; GO:0007601; GO:0033165; GO:0050896 47778 XM_029350431.2 1502 1105 1005 1408 1043 A0A2K5V015 7.35e-54 Protein eyes shut homolog (Epidermal growth factor-like protein 10) (EGF-like protein 10) (Epidermal growth factor-like protein 11) (EGF-like protein 11) (Protein spacemaker homolog) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) response to stimulus [GO:0050896]; visual perception [GO:0007601] GO:0001750; GO:0005509; GO:0005576; GO:0005737; GO:0005815; GO:0007601; GO:0033165; GO:0050896 47779 XM_029350431.2 1502 1105 1005 1408 1043 A0A2K5V015 3.05e-34 Protein eyes shut homolog (Epidermal growth factor-like protein 10) (EGF-like protein 10) (Epidermal growth factor-like protein 11) (EGF-like protein 11) (Protein spacemaker homolog) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) response to stimulus [GO:0050896]; visual perception [GO:0007601] GO:0001750; GO:0005509; GO:0005576; GO:0005737; GO:0005815; GO:0007601; GO:0033165; GO:0050896 47780 XM_044329322.1 494 310 184 423 648 Q7ZXV8 3.12e-49 BUB3-interacting and GLEBS motif-containing protein ZNF207 (BuGZ) (xBuGZ) (Zinc finger protein 207) Xenopus laevis (African clawed frog) attachment of spindle microtubules to kinetochore [GO:0008608]; cell division [GO:0051301]; microtubule bundle formation [GO:0001578]; microtubule polymerization [GO:0046785]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly [GO:0090307]; mitotic spindle assembly checkpoint signaling [GO:0007094]; protein stabilization [GO:0050821]; regulation of chromosome segregation [GO:0051983] GO:0000070; GO:0000776; GO:0001578; GO:0005634; GO:0005737; GO:0005819; GO:0005874; GO:0007094; GO:0008017; GO:0008608; GO:0046785; GO:0046872; GO:0050821; GO:0051301; GO:0051983; GO:0090307; GO:1990047 47781 XM_029357150.2 724 1172 759 701 398 Q8STF0 2.17e-34 Calmodulin (CaM) Strongylocentrotus intermedius (Sea urchin) NA GO:0005509 47782 XR_006391366.1 61 1 40 43 32 NA NA NA NA NA NA 47783 XM_044312531.1 191 33 11 66 103 NA NA NA NA NA NA 47784 XR_006392956.1 41 2 25 5 151 NA NA NA NA NA NA 47785 XM_044322508.1 0 22 0 64 122 NA NA NA NA NA NA 47786 XM_044318880.1 441 285 184 546 464 NA NA NA NA NA NA 47787 XR_006394407.1 134 77 94 233 281 NA NA NA NA NA NA 47788 XM_029327131.2 351 161 304 490 397 Q923X6 4.41e-24 Trace amine-associated receptor 7e (TaR-7e) (Trace amine receptor 7e) (Trace amine receptor 14) (TaR-14) Rattus norvegicus (Rat) NA GO:0001594; GO:0005886 47789 XM_044317912.1 121 22 40 78 78 O15439 0 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 47790 XR_006391379.1 242 95 363 155 659 Q9NQR9 1.26e-57 Glucose-6-phosphatase 2 (G-6-Pase 2) (G6Pase 2) (EC 3.1.3.9) (Islet-specific glucose-6-phosphatase catalytic subunit-related protein) Homo sapiens (Human) gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; regulation of insulin secretion [GO:0050796] GO:0004346; GO:0005789; GO:0006094; GO:0016020; GO:0042593; GO:0050796; GO:0051156 47791 XM_044306771.1 70 17 288 66 195 NA NA NA NA NA NA 47792 XM_044319423.1 2 1 19 5 11 P0CT39 7.36e-86 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 47793 XM_044314318.1 17514 7259 8077 11129 3082 NA NA NA NA NA NA 47794 XM_029324146.2 32 30 1 53 24 NA NA NA NA NA NA 47795 XM_044312259.1 122 116 90 175 140 NA NA NA NA NA NA 47796 XM_029343159.2 922 546 768 1177 1019 Q9UGM3 1.59e-56 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 47797 XM_029343159.2 922 546 768 1177 1019 Q9UGM3 7.53e-54 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 47798 XM_029343159.2 922 546 768 1177 1019 Q9UGM3 9.98e-54 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 47799 XM_029343159.2 922 546 768 1177 1019 Q9UGM3 6.93e-53 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 47800 XM_029343159.2 922 546 768 1177 1019 Q9UGM3 1.04e-52 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 47801 XM_029343159.2 922 546 768 1177 1019 Q9UGM3 3.97e-51 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 47802 XM_044324990.1 0 50 0 1 0 NA NA NA NA NA NA 47803 XM_044312782.1 19 28 0 0 32 P69478 5.9e-34 Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4S-1) (C4ST-1) (C4ST1) Rattus norvegicus (Rat) apoptotic process [GO:0006915]; carbohydrate biosynthetic process [GO:0016051]; cartilage development [GO:0051216]; chondrocyte development [GO:0002063]; chondroitin sulfate biosynthetic process [GO:0030206]; chondroitin sulfate metabolic process [GO:0030204]; developmental growth [GO:0048589]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; embryonic viscerocranium morphogenesis [GO:0048703]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; polysaccharide localization [GO:0033037]; post-anal tail morphogenesis [GO:0036342]; post-embryonic development [GO:0009791]; proteoglycan biosynthetic process [GO:0030166]; regulation of cell population proliferation [GO:0042127]; respiratory gaseous exchange by respiratory system [GO:0007585]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0000139; GO:0001537; GO:0001701; GO:0002063; GO:0006915; GO:0007179; GO:0007585; GO:0008146; GO:0009791; GO:0016051; GO:0030166; GO:0030204; GO:0030206; GO:0030326; GO:0030512; GO:0033037; GO:0036342; GO:0042127; GO:0042733; GO:0043066; GO:0047756; GO:0048589; GO:0048703; GO:0048704; GO:0050659; GO:0051216 47804 XM_029358380.2 2156 1870 1594 1635 1353 Q01890 6.14e-73 Ras-like GTP-binding protein YPT1 Phytophthora infestans (Potato late blight agent) (Botrytis infestans) autophagy [GO:0006914]; protein transport [GO:0015031] GO:0000139; GO:0003924; GO:0005525; GO:0005789; GO:0006914; GO:0015031; GO:0034045 47805 XM_044317833.1 64 12 169 128 206 C6KI89 4.2e-38 Cation channel sperm-associated auxiliary subunit gamma 2 Mus musculus (Mouse) cell differentiation [GO:0030154]; spermatogenesis [GO:0007283] GO:0007283; GO:0030154; GO:0031514; GO:0036128; GO:0097228 47806 XM_029335325.2 2437 1891 1517 3009 2934 Q96L93 0 Kinesin-like protein KIF16B (Sorting nexin-23) Homo sapiens (Human) early endosome to late endosome transport [GO:0045022]; endoderm development [GO:0007492]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; formation of primary germ layer [GO:0001704]; Golgi to endosome transport [GO:0006895]; microtubule-based movement [GO:0007018]; receptor catabolic process [GO:0032801]; regulation of receptor recycling [GO:0001919] GO:0001704; GO:0001919; GO:0003777; GO:0005524; GO:0005547; GO:0005737; GO:0005768; GO:0005769; GO:0005819; GO:0005829; GO:0005871; GO:0005874; GO:0006895; GO:0007018; GO:0007173; GO:0007492; GO:0008017; GO:0008543; GO:0008574; GO:0016887; GO:0031901; GO:0032266; GO:0032801; GO:0043325; GO:0045022; GO:0080025 47807 XM_044316666.1 103 100 97 207 138 E7FAM5 2.14e-66 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 47808 XM_029335485.2 782 1082 388 296 474 NA NA NA NA NA NA 47809 XR_003826808.2 14 5 27 40 96 NA NA NA NA NA NA 47810 XM_044313536.1 50 1 26 6 25 NA NA NA NA NA NA 47811 XM_029342141.2 65 57 17 17 26 NA NA NA NA NA NA 47812 XM_044321144.1 115 15 70 0 49 Q9NYT0 1.34e-45 Pleckstrin-2 Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; intracellular signal transduction [GO:0035556]; positive regulation of plasma membrane bounded cell projection assembly [GO:0120034] GO:0005737; GO:0005856; GO:0005886; GO:0031258; GO:0031532; GO:0032266; GO:0035556; GO:0043325; GO:0080025; GO:0120034 47813 XM_029326542.2 38 16 6 15 60 Q5HZE0 5.01e-64 Mitochondrial basic amino acids transporter (Carnitine/acylcarnitine translocase-like) (CACT-like) (Mitochondrial carnitine/acylcarnitine carrier protein CACL) (Mitochondrial ornithine transporter 3) (Solute carrier family 25 member 29) Rattus norvegicus (Rat) acyl carnitine transmembrane transport [GO:1902616]; acyl carnitine transport [GO:0006844]; cation transmembrane transport [GO:0098655]; L-arginine transmembrane transport [GO:1903826]; L-histidine transmembrane transport [GO:0089709]; L-lysine transmembrane transport [GO:1903401]; mitochondrial L-ornithine transmembrane transport [GO:1990575]; organic cation transport [GO:0015695]; ornithine transport [GO:0015822] GO:0005289; GO:0005292; GO:0005739; GO:0005743; GO:0006844; GO:0015174; GO:0015227; GO:0015695; GO:0015822; GO:0022857; GO:0089709; GO:0098655; GO:1902616; GO:1903401; GO:1903826; GO:1990575 47814 XM_029355660.2 33 193 154 191 232 P83553 4.21e-24 Dermatopontin (Tyrosine-rich acidic matrix protein) (TRAMP) Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail) cell adhesion [GO:0007155] GO:0005576; GO:0007155 47815 XM_044319228.1 181 1167 99 259 13 NA NA NA NA NA NA 47816 XM_029338626.2 2493 1980 1431 2495 2179 Q9WU70 7.89e-161 Syntaxin-binding protein 5 (Lethal(2) giant larvae protein homolog 3) (Tomosyn-1) Rattus norvegicus (Rat) exocytosis [GO:0006887]; positive regulation of exocytosis [GO:0045921]; protein transport [GO:0015031]; regulation of exocytosis [GO:0017157]; regulation of protein secretion [GO:0050708]; regulation of synaptic vesicle exocytosis [GO:2000300]; regulation of synaptic vesicle priming [GO:0010807]; synaptic vesicle cycle [GO:0099504] GO:0005096; GO:0005737; GO:0005886; GO:0005892; GO:0006887; GO:0008021; GO:0010807; GO:0015031; GO:0017075; GO:0017157; GO:0019905; GO:0030141; GO:0031201; GO:0031594; GO:0045159; GO:0045921; GO:0050708; GO:0098674; GO:0098685; GO:0098686; GO:0098793; GO:0098888; GO:0099504; GO:0099523; GO:2000300 47817 XM_029338626.2 2493 1980 1431 2495 2179 Q9WU70 5.07e-53 Syntaxin-binding protein 5 (Lethal(2) giant larvae protein homolog 3) (Tomosyn-1) Rattus norvegicus (Rat) exocytosis [GO:0006887]; positive regulation of exocytosis [GO:0045921]; protein transport [GO:0015031]; regulation of exocytosis [GO:0017157]; regulation of protein secretion [GO:0050708]; regulation of synaptic vesicle exocytosis [GO:2000300]; regulation of synaptic vesicle priming [GO:0010807]; synaptic vesicle cycle [GO:0099504] GO:0005096; GO:0005737; GO:0005886; GO:0005892; GO:0006887; GO:0008021; GO:0010807; GO:0015031; GO:0017075; GO:0017157; GO:0019905; GO:0030141; GO:0031201; GO:0031594; GO:0045159; GO:0045921; GO:0050708; GO:0098674; GO:0098685; GO:0098686; GO:0098793; GO:0098888; GO:0099504; GO:0099523; GO:2000300 47818 XR_006392000.1 91 17 0 23 171 NA NA NA NA NA NA 47819 XM_044318292.1 348 1961 1294 3622 3818 NA NA NA NA NA NA 47820 XM_029342648.2 914 325 637 850 759 Q96RW7 4.11e-37 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 47821 XM_029342648.2 914 325 637 850 759 Q96RW7 2.19e-31 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 47822 XM_029342648.2 914 325 637 850 759 Q96RW7 8.07e-31 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 47823 XM_029342648.2 914 325 637 850 759 Q96RW7 8.8e-25 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 47824 XM_029333761.2 473 213 254 344 237 F1NZI4 1.12e-144 Protein-glucosylgalactosylhydroxylysine glucosidase (EC 3.2.1.107) (Acid trehalase-like protein 1) Gallus gallus (Chicken) carbohydrate metabolic process [GO:0005975] GO:0004553; GO:0005829; GO:0005975; GO:0047402 47825 XR_006395738.1 121 0 60 87 0 NA NA NA NA NA NA 47826 XM_044326388.1 2175 1480 1187 3100 1618 Q4H3K6 1.23e-74 Fibroblast growth factor receptor (Ci-FGFR) (EC 2.7.10.1) Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis) positive regulation of cell population proliferation [GO:0008284]; positive regulation of kinase activity [GO:0033674]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0004714; GO:0005007; GO:0005524; GO:0005886; GO:0007169; GO:0008284; GO:0017134; GO:0033674; GO:0043235 47827 XM_029341465.2 0 20 0 45 0 Q9EQD2 2.39e-25 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 47828 XM_044327786.1 0 6 0 0 0 NA NA NA NA NA NA 47829 XM_044315827.1 37 3 13 9 0 NA NA NA NA NA NA 47830 XM_044319813.1 0 0 0 0 42 Q2KHY5 4.3e-36 Fanconi anemia core complex-associated protein 24 (Fanconi anemia-associated protein of 24 kDa) Bos taurus (Bovine) interstrand cross-link repair [GO:0036297] GO:0000785; GO:0003677; GO:0003682; GO:0005654; GO:0036297; GO:0043240; GO:0071821 47831 XM_044320231.1 59 2 44 1 105 NA NA NA NA NA NA 47832 XM_044323535.1 1 19 23 17 0 NA NA NA NA NA NA 47833 XM_044311811.1 12581 9609 7996 13877 13100 Q02218 0 2-oxoglutarate dehydrogenase complex component E1 (E1o) (OGDC-E1) (OGDH-E1) (EC 1.2.4.2) (2-oxoglutarate dehydrogenase, mitochondrial) (Alpha-ketoglutarate dehydrogenase) (Alpha-KGDH-E1) (Thiamine diphosphate (ThDP)-dependent 2-oxoglutarate dehydrogenase) Homo sapiens (Human) 2-oxoglutarate metabolic process [GO:0006103]; cerebellar cortex development [GO:0021695]; generation of precursor metabolites and energy [GO:0006091]; glycolytic process [GO:0006096]; hippocampus development [GO:0021766]; histone succinylation [GO:0106077]; NADH metabolic process [GO:0006734]; olfactory bulb mitral cell layer development [GO:0061034]; pyramidal neuron development [GO:0021860]; striatum development [GO:0021756]; succinyl-CoA metabolic process [GO:0006104]; tangential migration from the subventricular zone to the olfactory bulb [GO:0022028]; thalamus development [GO:0021794]; tricarboxylic acid cycle [GO:0006099] GO:0004591; GO:0005634; GO:0005739; GO:0005759; GO:0006091; GO:0006096; GO:0006099; GO:0006103; GO:0006104; GO:0006734; GO:0021695; GO:0021756; GO:0021766; GO:0021794; GO:0021860; GO:0022028; GO:0030976; GO:0031072; GO:0031966; GO:0034602; GO:0045252; GO:0046872; GO:0051087; GO:0061034; GO:0106077 47834 XM_029337301.2 22212 9810 13392 29039 23467 Q964E3 0 Actin, cytoplasmic (EC 3.6.4.-) [Cleaved into: Actin, cytoplasmic, intermediate form] Biomphalaria alexandrina (Bloodfluke planorb) (Freshwater snail) NA GO:0005524; GO:0005737; GO:0005856; GO:0016787 47835 XM_029350581.2 337 253 154 449 416 Q9Z2I0 1.33e-124 Mitochondrial proton/calcium exchanger protein (Leucine zipper-EF-hand-containing transmembrane protein 1) Mus musculus (Mouse) calcium export from the mitochondrion [GO:0099093]; cellular metal ion homeostasis [GO:0006875]; cristae formation [GO:0042407]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrial calcium ion transmembrane transport [GO:0006851]; negative regulation of mitochondrial calcium ion concentration [GO:0051562]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; regulation of cellular hyperosmotic salinity response [GO:1900069] GO:0005739; GO:0005743; GO:0006851; GO:0006875; GO:0015369; GO:0034214; GO:0042407; GO:0043022; GO:0046872; GO:0051260; GO:0051560; GO:0051562; GO:0099093; GO:1900069 47836 XM_044306916.1 1042 103 1116 879 215 NA NA NA NA NA NA 47837 XM_029332396.2 1968 1661 3430 2354 1644 E7E2N8 4.18e-56 Gamma-interferon-inducible lysosomal thiol reductase (EC 1.8.-.-) Carassius auratus (Goldfish) antigen processing and presentation [GO:0019882] GO:0005576; GO:0005764; GO:0016671; GO:0019882; GO:0047134 47838 XM_029333522.2 99 120 81 99 330 B8VIU6 1.49e-41 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 47839 XM_029328590.2 212 149 67 116 182 Q8TB40 1.25e-116 (Lyso)-N-acylphosphatidylethanolamine lipase (EC 3.1.1.-) (Alpha/beta hydrolase domain-containing protein 4) (Abhydrolase domain-containing protein 4) (Alpha/beta-hydrolase 4) Homo sapiens (Human) lipid catabolic process [GO:0016042]; lipid homeostasis [GO:0055088]; N-acylphosphatidylethanolamine metabolic process [GO:0070292]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152] GO:0004622; GO:0005739; GO:0005789; GO:0005811; GO:0006654; GO:0016042; GO:0016787; GO:0036152; GO:0042171; GO:0055088; GO:0070292 47840 XM_029339126.2 1787 1213 965 1149 1323 Q9D4C5 3.84e-21 ELL-associated factor 1 Mus musculus (Mouse) positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription elongation by RNA polymerase II [GO:0034243]; transcription elongation by RNA polymerase II promoter [GO:0006368] GO:0003711; GO:0005634; GO:0005654; GO:0006368; GO:0008023; GO:0015030; GO:0016604; GO:0016607; GO:0032783; GO:0034243; GO:0043231; GO:0045171; GO:0045944 47841 XM_044313207.1 10 208 0 0 356 NA NA NA NA NA NA 47842 XM_044308416.1 2092 3257 3086 3181 1385 Q54PI5 1.52e-39 Probable gluconokinase (EC 2.7.1.12) (Gluconate kinase) Dictyostelium discoideum (Social amoeba) D-gluconate catabolic process [GO:0046177]; phosphorylation [GO:0016310] GO:0005524; GO:0016310; GO:0046177; GO:0046316 47843 XM_029330623.2 1026 736 769 938 1301 Q7Z589 1.06e-36 BRCA2-interacting transcriptional repressor EMSY Homo sapiens (Human) chromatin organization [GO:0006325]; DNA repair [GO:0006281]; regulation of DNA-templated transcription [GO:0006355] GO:0005654; GO:0006281; GO:0006325; GO:0006355 47844 XM_029337840.2 0 0 0 164 0 O75762 2.19e-82 Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation-sensitive protein p120) (p120) (Wasabi receptor) Homo sapiens (Human) calcium ion transmembrane transport [GO:0070588]; cell surface receptor signaling pathway [GO:0007166]; cellular calcium ion homeostasis [GO:0006874]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to organic substance [GO:0071310]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; ion transport [GO:0006811]; protein homotetramerization [GO:0051289]; response to cold [GO:0009409]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; sensory perception of pain [GO:0019233]; thermoception [GO:0050955] GO:0005262; GO:0005886; GO:0006811; GO:0006874; GO:0007166; GO:0009409; GO:0009410; GO:0010033; GO:0014070; GO:0015267; GO:0015278; GO:0019233; GO:0032421; GO:0042802; GO:0048265; GO:0050955; GO:0050966; GO:0050968; GO:0051289; GO:0070301; GO:0070588; GO:0071310; GO:0097604 47845 XR_006397764.1 66 28 36 10 27 NA NA NA NA NA NA 47846 XR_006391649.1 4695 3030 1989 2403 1952 NA NA NA NA NA NA 47847 XR_006393333.1 71 18 31 45 11 NA NA NA NA NA NA 47848 XM_029325163.2 1430 869 805 1326 1199 Q28CZ7 1.17e-81 D-ribitol-5-phosphate cytidylyltransferase (EC 2.7.7.40) (2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase-like protein) (Isoprenoid synthase domain-containing protein) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) brain morphogenesis [GO:0048854]; isoprenoid biosynthetic process [GO:0008299]; protein O-linked mannosylation [GO:0035269]; regulation of protein glycosylation [GO:0060049] GO:0005829; GO:0008299; GO:0035269; GO:0042803; GO:0047349; GO:0048854; GO:0060049; GO:0070567 47849 XM_029356119.2 813 577 543 882 508 NA NA NA NA NA NA 47850 XM_029358582.2 23 0 0 0 0 Q3KR59 1.13e-109 Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.4.19.12) (Deubiquitinating enzyme 10) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) Rattus norvegicus (Rat) autophagy [GO:0006914]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to interleukin-1 [GO:0071347]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA repair [GO:0006281]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; protein deubiquitination [GO:0016579]; regulation of autophagy [GO:0010506]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0002039; GO:0004197; GO:0004843; GO:0005634; GO:0005737; GO:0005769; GO:0005829; GO:0006281; GO:0006511; GO:0006914; GO:0006974; GO:0010506; GO:0016579; GO:0030330; GO:0032991; GO:0043124; GO:0044325; GO:0071347 47851 XM_029337510.2 371 340 156 132 154 P49005 1.77e-159 DNA polymerase delta subunit 2 (DNA polymerase delta subunit p50) Homo sapiens (Human) DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; DNA strand elongation involved in DNA replication [GO:0006271]; DNA-templated DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276] GO:0003677; GO:0005634; GO:0005654; GO:0006260; GO:0006261; GO:0006271; GO:0016035; GO:0042276; GO:0042575; GO:0043625; GO:0071897 47852 XM_029336884.2 0 0 3 0 29 Q94K49 1.2e-34 Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1 (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) epigenetic regulation of gene expression [GO:0040029] GO:0003682; GO:0004518; GO:0005634; GO:0035098; GO:0035102; GO:0040029; GO:0046872 47853 XM_029336746.2 248 211 83 185 118 NA NA NA NA NA NA 47854 XM_029352125.2 181 77 33 157 62 NA NA NA NA NA NA 47855 XM_029347366.2 249 49 52 71 86 NA NA NA NA NA NA 47856 XM_044317232.1 21 13 47 16 199 Q94887 4.24e-34 Neurexin-4 (Neurexin IV) Drosophila melanogaster (Fruit fly) axon ensheathment [GO:0008366]; cell adhesion involved in heart morphogenesis [GO:0061343]; cell-cell junction organization [GO:0045216]; dorsal closure [GO:0007391]; establishment of glial blood-brain barrier [GO:0060857]; heart process [GO:0003015]; nerve maturation [GO:0021682]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]; synaptic target recognition [GO:0008039]; terminal button organization [GO:0072553] GO:0003015; GO:0005886; GO:0005919; GO:0007391; GO:0008039; GO:0008104; GO:0008366; GO:0019991; GO:0021682; GO:0035151; GO:0045202; GO:0045216; GO:0048786; GO:0060857; GO:0061343; GO:0072553; GO:0097105 47857 XM_029356202.2 240 192 143 248 208 NA NA NA NA NA NA 47858 XM_044325010.1 1 20 10 3 0 Q9MYW9 1.65e-22 Mu-type opioid receptor (M-OR-1) (MOR-1) Macaca mulatta (Rhesus macaque) adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway [GO:0007197]; G protein-coupled opioid receptor signaling pathway [GO:0038003]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of Wnt protein secretion [GO:0061358]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neurogenesis [GO:0050769]; regulation of NMDA receptor activity [GO:2000310]; sensory perception of pain [GO:0019233] GO:0001965; GO:0004930; GO:0004979; GO:0005245; GO:0005768; GO:0005886; GO:0007197; GO:0007200; GO:0007218; GO:0019233; GO:0030424; GO:0030425; GO:0031681; GO:0038003; GO:0038047; GO:0042277; GO:0042923; GO:0043005; GO:0043204; GO:0043951; GO:0045019; GO:0045202; GO:0050769; GO:0051481; GO:0061358; GO:0070374; GO:2000310 47859 XM_044307269.1 0 0 56 21 47 NA NA NA NA NA NA 47860 XM_029334155.2 3531 2414 2228 3666 3948 Q66II8 1.11e-64 U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (U1-70K) (snRNP70) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) mRNA splicing, via spliceosome [GO:0000398]; regulation of RNA splicing [GO:0043484] GO:0000398; GO:0003723; GO:0005634; GO:0005681; GO:0005685; GO:0016607; GO:0030619; GO:0043484 47861 XR_003825144.2 124 80 3 11 66 NA NA NA NA NA NA 47862 XM_044323093.1 330 810 1660 1074 1508 Q5E9T4 2.09e-67 Thiamin pyrophosphokinase 1 (EC 2.7.6.2) (Thiamine pyrophosphokinase 1) Bos taurus (Bovine) phosphorylation [GO:0016310]; thiamine diphosphate biosynthetic process [GO:0009229]; thiamine metabolic process [GO:0006772] GO:0004788; GO:0005524; GO:0006772; GO:0009229; GO:0016301; GO:0016310; GO:0030975; GO:0042802 47863 XM_044318934.1 103 12 33 49 0 O64411 2.81e-70 Polyamine oxidase 1 (EC 1.5.3.14) (EC 1.5.3.15) Zea mays (Maize) polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208] GO:0006598; GO:0009505; GO:0016491; GO:0046208; GO:0046592; GO:0048046; GO:0050660; GO:0052893; GO:0052896; GO:0052897; GO:0052900 47864 XM_044314847.1 12 2 1 6 29 NA NA NA NA NA NA 47865 XM_029356658.2 363 474 400 435 370 Q9EPI6 4.69e-50 NMDA receptor synaptonuclear signaling and neuronal migration factor (Juxtasynaptic attractor of caldendrin on dendritic boutons protein) (Jacob protein) (Nasal embryonic luteinizing hormone-releasing hormone factor) (Nasal embryonic LHRH factor) Rattus norvegicus (Rat) cellular response to amino acid stimulus [GO:0071230]; cellular response to electrical stimulus [GO:0071257]; cellular response to gonadotropin stimulus [GO:0071371]; positive regulation of neuron migration [GO:2001224]; positive regulation of protein dephosphorylation [GO:0035307]; postsynapse to nucleus signaling pathway [GO:0099527]; regulation of dendrite morphogenesis [GO:0048814]; regulation of neuron apoptotic process [GO:0043523]; regulation of neuronal synaptic plasticity [GO:0048168] GO:0000791; GO:0005634; GO:0005635; GO:0005737; GO:0005886; GO:0014069; GO:0016020; GO:0016363; GO:0030425; GO:0030863; GO:0031965; GO:0035307; GO:0043005; GO:0043197; GO:0043204; GO:0043523; GO:0045202; GO:0048168; GO:0048306; GO:0048814; GO:0071230; GO:0071257; GO:0071371; GO:0097440; GO:0098794; GO:0098978; GO:0099527; GO:2001224 47866 XM_044309063.1 44 33 18 39 54 Q3UQ28 3.44e-30 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 47867 XM_044309063.1 44 33 18 39 54 Q3UQ28 3.44e-24 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 47868 XM_044308637.1 1319 1132 714 933 557 Q9CZU3 0 Exosome RNA helicase MTR4 (EC 3.6.4.13) (ATP-dependent helicase SKIV2L2) (Superkiller viralicidic activity 2-like 2) (TRAMP-like complex helicase) Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; maturation of 5.8S rRNA [GO:0000460]; mRNA processing [GO:0006397]; RNA catabolic process [GO:0006401]; RNA splicing [GO:0008380]; rRNA processing [GO:0006364] GO:0000176; GO:0000178; GO:0000460; GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0006364; GO:0006397; GO:0006401; GO:0006974; GO:0008380; GO:0016607; GO:0016887; GO:0031499; GO:0071013 47869 XM_044312141.1 0 3 9 47 8 NA NA NA NA NA NA 47870 XM_044309719.1 22 0 7 9 62 NA NA NA NA NA NA 47871 XM_044312138.1 0 0 18 0 0 NA NA NA NA NA NA 47872 XM_044309149.1 71 58 2 97 137 C3YZ51 3.09e-171 Ubiquitin-like modifier-activating enzyme 5 (Ubiquitin-activating enzyme 5) Branchiostoma floridae (Florida lancelet) (Amphioxus) protein modification by small protein conjugation [GO:0032446]; protein ufmylation [GO:0071569] GO:0005524; GO:0005737; GO:0005829; GO:0032446; GO:0046872; GO:0071566; GO:0071569 47873 XM_044322742.1 13 0 0 31 1 NA NA NA NA NA NA 47874 XM_044317016.1 14 0 0 0 1 Q9N126 3.15e-65 Retinol dehydrogenase 8 (EC 1.1.1.300) (Photoreceptor outer segment all-trans retinol dehydrogenase) Bos taurus (Bovine) estrogen biosynthetic process [GO:0006703]; response to stimulus [GO:0050896]; retinol metabolic process [GO:0042572]; visual perception [GO:0007601] GO:0004303; GO:0004745; GO:0005829; GO:0006703; GO:0007601; GO:0016491; GO:0042572; GO:0042622; GO:0050896; GO:0052650 47875 XM_029339777.2 0 520 693 825 129 Q8K370 0 Acyl-CoA dehydrogenase family member 10 (ACAD-10) (EC 1.3.99.-) Mus musculus (Mouse) fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539] GO:0003995; GO:0005737; GO:0005739; GO:0033539; GO:0050660 47876 XM_044319503.1 127 0 19 32 55 Q99315 1.89e-94 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 47877 XM_029326342.2 77 21 91 38 365 NA NA NA NA NA NA 47878 XM_029340197.2 12 0 0 24 0 Q3U821 2.87e-118 WD repeat-containing protein 75 (U3 small nucleolar RNA-associated protein 17 homolog) Mus musculus (Mouse) positive regulation of rRNA processing [GO:2000234]; positive regulation of transcription by RNA polymerase I [GO:0045943]; rRNA processing [GO:0006364] GO:0003723; GO:0005730; GO:0006364; GO:0045943; GO:2000234 47879 XM_044311571.1 0 0 0 0 7 NA NA NA NA NA NA 47880 XM_029339481.2 149 604 0 392 0 Q91827 3.55e-23 Apoptosis regulator R1 (XR1) Xenopus laevis (African clawed frog) apoptotic process [GO:0006915]; regulation of apoptotic process [GO:0042981] GO:0006915; GO:0016020; GO:0042981 47881 XM_044318648.1 309 177 106 180 613 NA NA NA NA NA NA 47882 XM_044310047.1 170 0 164 160 0 Q28824 5.26e-75 Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form] Bos taurus (Bovine) protein phosphorylation [GO:0006468]; tonic smooth muscle contraction [GO:0014820] GO:0001725; GO:0003779; GO:0004672; GO:0004687; GO:0005516; GO:0005524; GO:0005737; GO:0006468; GO:0014820; GO:0030027; GO:0032154; GO:0046872 47883 XM_044321162.1 9 0 0 0 0 NA NA NA NA NA NA 47884 XM_029333041.2 270 208 211 405 451 Q2KHT8 7.96e-167 Probable dimethyladenosine transferase (EC 2.1.1.183) (DIM1 dimethyladenosine transferase 1 homolog) (DIM1 dimethyladenosine transferase 1-like) (Probable 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase) (Probable 18S rRNA dimethylase) (Probable S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase) Bos taurus (Bovine) positive regulation of rRNA processing [GO:2000234]; rRNA methylation [GO:0031167] GO:0000179; GO:0003723; GO:0005654; GO:0005730; GO:0005829; GO:0031167; GO:0052909; GO:2000234 47885 XM_029357735.2 31 0 8 15 54 NA NA NA NA NA NA 47886 XR_006398075.1 133 29 99 55 312 Q1JPS6 6.05e-21 Melanopsin-like (Melanopsin) (Opsin-4-like) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to light stimulus [GO:0071482]; G protein-coupled receptor signaling pathway [GO:0007186]; light-induced release of internally sequestered calcium ion [GO:0008377]; phototransduction [GO:0007602]; visual perception [GO:0007601] GO:0005886; GO:0007186; GO:0007601; GO:0007602; GO:0008020; GO:0008377; GO:0009881; GO:0071482 47887 XR_006398075.1 133 29 99 55 312 Q1JPS6 6.05e-21 Melanopsin-like (Melanopsin) (Opsin-4-like) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to light stimulus [GO:0071482]; G protein-coupled receptor signaling pathway [GO:0007186]; light-induced release of internally sequestered calcium ion [GO:0008377]; phototransduction [GO:0007602]; visual perception [GO:0007601] GO:0005886; GO:0007186; GO:0007601; GO:0007602; GO:0008020; GO:0008377; GO:0009881; GO:0071482 47888 XM_044328567.1 677 1375 327 586 369 Q5ZKJ4 1.53e-40 FGFR1 oncogene partner 2 homolog Gallus gallus (Chicken) response to wounding [GO:0009611] GO:0005737; GO:0009611 47889 XM_029342998.2 4018 3300 1573 2798 2366 Q6P8X1 2.61e-180 Sorting nexin-6 [Cleaved into: Sorting nexin-6, N-terminally processed] Mus musculus (Mouse) cellular response to amyloid-beta [GO:1904646]; cellular response to epidermal growth factor stimulus [GO:0071364]; intracellular protein transport [GO:0006886]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; retrograde transport, endosome to Golgi [GO:0042147] GO:0005634; GO:0005737; GO:0005764; GO:0005768; GO:0005829; GO:0006886; GO:0030512; GO:0030904; GO:0031901; GO:0034452; GO:0034713; GO:0035091; GO:0042147; GO:0042803; GO:0043524; GO:0045892; GO:0071364; GO:0097422; GO:0098978; GO:0099072; GO:1904646 47890 XM_029338076.2 1581 1630 1027 1922 2358 Q75V66 0 Anoctamin-5 (Gnathodiaphyseal dysplasia 1 protein) (Transmembrane protein 16E) Homo sapiens (Human) chloride transmembrane transport [GO:1902476]; chloride transport [GO:0006821]; ion transmembrane transport [GO:0034220]; transmembrane transport [GO:0055085] GO:0005229; GO:0005254; GO:0005789; GO:0005886; GO:0006821; GO:0031982; GO:0034220; GO:0046983; GO:0055085; GO:1902476 47891 XM_044327432.1 31 19 24 14 17 NA NA NA NA NA NA 47892 XM_044313041.1 7 9 11 20 4 Q96AY4 5.44e-92 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 47893 XM_044313041.1 7 9 11 20 4 Q96AY4 1.41e-85 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 47894 XM_044313041.1 7 9 11 20 4 Q96AY4 2.22e-82 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 47895 XM_044313041.1 7 9 11 20 4 Q96AY4 3.47e-81 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 47896 XM_044313041.1 7 9 11 20 4 Q96AY4 2.85e-80 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 47897 XM_044313041.1 7 9 11 20 4 Q96AY4 4.74e-79 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 47898 XM_044313041.1 7 9 11 20 4 Q96AY4 4.55e-78 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 47899 XM_044313041.1 7 9 11 20 4 Q96AY4 8.81e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 47900 XM_044313041.1 7 9 11 20 4 Q96AY4 4.08e-72 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 47901 XM_044313041.1 7 9 11 20 4 Q96AY4 1.04e-69 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 47902 XM_044313041.1 7 9 11 20 4 Q96AY4 2.84e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 47903 XM_029341339.2 238 482 300 239 280 NA NA NA NA NA NA 47904 XM_029325627.2 161 37 19 51 38 NA NA NA NA NA NA 47905 XM_029345898.2 0 0 44 31 0 Q059U7 5.24e-158 Protein inturned (Inturned planar cell polarity effector homolog) (PDZ domain-containing protein 6) Mus musculus (Mouse) cell division [GO:0051301]; cilium assembly [GO:0060271]; embryonic digit morphogenesis [GO:0042733]; establishment of planar polarity [GO:0001736]; hair follicle morphogenesis [GO:0031069]; intraciliary transport [GO:0042073]; keratinocyte differentiation [GO:0030216]; limb development [GO:0060173]; motile cilium assembly [GO:0044458]; negative regulation of cell division [GO:0051782]; negative regulation of keratinocyte proliferation [GO:0010839]; nervous system development [GO:0007399]; neural tube development [GO:0021915]; non-motile cilium assembly [GO:1905515]; positive regulation of smoothened signaling pathway [GO:0045880]; protein localization to organelle [GO:0033365]; regulation of cilium assembly [GO:1902017]; regulation of ossification [GO:0030278]; regulation of smoothened signaling pathway [GO:0008589]; roof of mouth development [GO:0060021]; smoothened signaling pathway [GO:0007224]; spinal cord dorsal/ventral patterning [GO:0021513]; tongue morphogenesis [GO:0043587]; vesicle-mediated transport [GO:0016192] GO:0001736; GO:0005737; GO:0005814; GO:0005929; GO:0007224; GO:0007399; GO:0008589; GO:0009986; GO:0010839; GO:0016192; GO:0021513; GO:0021915; GO:0030216; GO:0030278; GO:0031069; GO:0031514; GO:0033365; GO:0035869; GO:0036064; GO:0042073; GO:0042733; GO:0043587; GO:0044458; GO:0045880; GO:0051301; GO:0051782; GO:0060021; GO:0060173; GO:0060271; GO:1902017; GO:1905515 47906 XM_044308688.1 936 336 557 2191 1323 D3YXG0 2.68e-66 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 47907 XM_044308688.1 936 336 557 2191 1323 D3YXG0 1.95e-51 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 47908 XM_044308688.1 936 336 557 2191 1323 D3YXG0 1.72e-47 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 47909 XM_044308688.1 936 336 557 2191 1323 D3YXG0 4.3e-42 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 47910 XM_044308688.1 936 336 557 2191 1323 D3YXG0 2.67e-40 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 47911 XM_044308688.1 936 336 557 2191 1323 D3YXG0 5.17e-40 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 47912 XM_044308688.1 936 336 557 2191 1323 D3YXG0 3.02e-39 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 47913 XM_044308688.1 936 336 557 2191 1323 D3YXG0 3.45e-38 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 47914 XM_044308688.1 936 336 557 2191 1323 D3YXG0 1.66e-37 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 47915 XM_044308688.1 936 336 557 2191 1323 D3YXG0 1.07e-36 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 47916 XM_044308688.1 936 336 557 2191 1323 D3YXG0 1.38e-33 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 47917 XM_044312049.1 36 17 19 44 35 NA NA NA NA NA NA 47918 XM_029331329.2 0 0 15 50 38 Q9YH18 1.61e-59 KH domain-containing RNA-binding protein QKI (Protein quaking) Gallus gallus (Chicken) long-chain fatty acid biosynthetic process [GO:0042759]; mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; myelination [GO:0042552]; positive regulation of gene expression [GO:0010628]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of translation [GO:0006417]; RNA splicing [GO:0008380]; spermatid development [GO:0007286]; vascular associated smooth muscle cell differentiation [GO:0035886]; vasculogenesis [GO:0001570] GO:0001570; GO:0003729; GO:0005634; GO:0005737; GO:0006397; GO:0006417; GO:0007286; GO:0008380; GO:0010628; GO:0017124; GO:0035886; GO:0042552; GO:0042759; GO:0045202; GO:0048024; GO:0051028 47919 XM_029356152.2 26666 13141 13087 15308 14300 Q26534 1.17e-112 Cathepsin L (EC 3.4.22.15) (SMCL1) Schistosoma mansoni (Blood fluke) proteolysis [GO:0006508] GO:0004197; GO:0005764; GO:0006508 47920 XM_044310095.1 24 9 27 73 57 Q3UQ28 1.29e-30 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 47921 XM_044310095.1 24 9 27 73 57 Q3UQ28 4.52e-29 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 47922 XM_044310095.1 24 9 27 73 57 Q3UQ28 9.33e-27 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 47923 XM_044310095.1 24 9 27 73 57 Q3UQ28 2.98e-25 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 47924 XM_044310403.1 70 726 220 294 12 NA NA NA NA NA NA 47925 XM_029328262.2 0 6 0 0 16 Q5ZJP7 6.23e-28 BTB/POZ domain-containing protein KCTD7 Gallus gallus (Chicken) membrane hyperpolarization [GO:0060081]; positive regulation of transporter activity [GO:0032411]; protein homooligomerization [GO:0051260] GO:0005829; GO:0005886; GO:0032411; GO:0051260; GO:0060081 47926 XM_044314389.1 936 41 150 1690 1063 Q9NZJ4 0 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 47927 XM_029352690.2 461 0 0 240 381 NA NA NA NA NA NA 47928 XM_044315087.1 1 0 16 0 0 NA NA NA NA NA NA 47929 XM_029345334.2 19 71 18 22 18 NA NA NA NA NA NA 47930 XM_044329163.1 30 193 21 0 22 NA NA NA NA NA NA 47931 XM_029357747.2 36 79 24 42 31 B2ZI34 6.51e-21 Neuromedin-B receptor (NMB-R) (Neuromedin-B-preferring bombesin receptor) Sus scrofa (Pig) antiviral innate immune response [GO:0140374]; negative regulation of interleukin-6 production [GO:0032715]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of osteoclast proliferation [GO:0090290]; positive regulation of respiratory gaseous exchange [GO:1903942]; sneeze reflex [GO:0160023] GO:0004946; GO:0005829; GO:0005886; GO:0032715; GO:0032727; GO:0090290; GO:0140374; GO:0160023; GO:1903942 47932 XM_044322381.1 0 0 0 14 0 Q5BKR2 2.48e-110 Sodium/hydrogen exchanger 9B2 (NHA-oc) (Na(+)/H(+) exchanger NHA2) (Na(+)/H(+) exchanger-like domain-containing protein 2) (NHE domain-containing protein 2) (Soditlum/hydrogen exchanger-like domain-containing protein 2) (Solute carrier family 9 subfamily B member 2) Mus musculus (Mouse) clathrin-dependent endocytosis [GO:0072583]; flagellated sperm motility [GO:0030317]; positive regulation of osteoclast development [GO:2001206]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; sodium ion transport [GO:0006814] GO:0005886; GO:0006814; GO:0010008; GO:0010348; GO:0015385; GO:0016323; GO:0030317; GO:0030672; GO:0031966; GO:0042802; GO:0061178; GO:0072583; GO:0097228; GO:2001206 47933 XM_029354792.2 233 889 104 90 21 NA NA NA NA NA NA 47934 XM_044307985.1 13 3 62 87 30 NA NA NA NA NA NA 47935 XM_044319013.1 925 156 0 198 290 Q09328 0 Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (EC 2.4.1.155) (Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase V) (GlcNAc-T V) (GNT-V) (Mannoside acetylglucosaminyltransferase 5) (N-acetylglucosaminyl-transferase V) [Cleaved into: Secreted alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (Secreted beta-1,6-N-acetylglucosaminyltransferase V) (Secreted GNT-V)] Homo sapiens (Human) negative regulation of protein tyrosine phosphatase activity [GO:1903614]; positive regulation of cell migration [GO:0030335]; positive regulation of receptor signaling pathway via STAT [GO:1904894]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279]; viral protein processing [GO:0019082] GO:0000139; GO:0004864; GO:0005794; GO:0006487; GO:0016020; GO:0018279; GO:0019082; GO:0030144; GO:0030145; GO:0030335; GO:0070062; GO:1903614; GO:1904894 47936 XM_029351609.2 120 27 52 81 206 NA NA NA NA NA NA 47937 XR_003828034.2 0 0 0 0 6 NA NA NA NA NA NA 47938 XM_029357040.2 1838 1651 525 600 1492 NA NA NA NA NA NA 47939 XM_029335960.2 508 54 110 167 432 Q8R0V5 1.25e-58 Indoleamine 2,3-dioxygenase 2 (IDO-2) (EC 1.13.11.-) (Indoleamine 2,3-dioxygenase-like protein 1) (Indoleamine-pyrrole 2,3-dioxygenase-like protein 1) Mus musculus (Mouse) 'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; immune system process [GO:0002376]; tryptophan catabolic process to kynurenine [GO:0019441] GO:0002376; GO:0004833; GO:0005737; GO:0019441; GO:0020037; GO:0033754; GO:0034354; GO:0046872 47940 XR_006396534.1 208 132 57 173 137 Q9YH16 2.1e-34 LIM domain only protein 3 (LMO-3) (LIM domain only protein 1) (LMO-1) (xLMO1) Xenopus laevis (African clawed frog) NA GO:0046872 47941 XR_006396534.1 208 132 57 173 137 Q9YH16 2.1e-34 LIM domain only protein 3 (LMO-3) (LIM domain only protein 1) (LMO-1) (xLMO1) Xenopus laevis (African clawed frog) NA GO:0046872 47942 XM_029340188.2 79 56 22 33 55 NA NA NA NA NA NA 47943 XM_029343216.2 203 92 175 94 56 NA NA NA NA NA NA 47944 XM_029350796.2 19 19 12 3 25 Q640F2 2.76e-56 SHC SH2 domain-binding protein 1 homolog B Xenopus laevis (African clawed frog) fibroblast growth factor receptor signaling pathway [GO:0008543]; regulation of neural precursor cell proliferation [GO:2000177] GO:0005737; GO:0005819; GO:0008543; GO:0030496; GO:2000177 47945 XM_029331494.2 189 57 68 173 174 O14770 2.29e-108 Homeobox protein Meis2 (Meis1-related protein 1) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; brain development [GO:0007420]; embryonic pattern specification [GO:0009880]; eye development [GO:0001654]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas development [GO:0031016]; positive regulation of cardiac muscle myoblast proliferation [GO:0110024]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; response to growth factor [GO:0070848]; response to mechanical stimulus [GO:0009612]; visual learning [GO:0008542] GO:0000122; GO:0000785; GO:0000978; GO:0000981; GO:0001228; GO:0001654; GO:0003677; GO:0005634; GO:0006357; GO:0007420; GO:0008134; GO:0008284; GO:0008542; GO:0009612; GO:0009880; GO:0009887; GO:0031016; GO:0043565; GO:0045638; GO:0045931; GO:0045944; GO:0048471; GO:0070848; GO:0110024; GO:1990837 47946 XM_044321094.1 282 155 278 559 537 Q9NZJ4 0 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 47947 XM_044307270.1 289 255 164 196 434 NA NA NA NA NA NA 47948 XM_029334305.2 2414 31 10 2916 7 NA NA NA NA NA NA 47949 XM_029344511.2 150 24 172 115 331 P0C6B8 0 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 47950 XM_029344511.2 150 24 172 115 331 P0C6B8 1.37e-57 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 47951 XM_029344511.2 150 24 172 115 331 P0C6B8 3.73e-56 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 47952 XM_029344511.2 150 24 172 115 331 P0C6B8 2.91e-49 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 47953 XM_029344511.2 150 24 172 115 331 P0C6B8 7.29e-49 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 47954 XM_029344511.2 150 24 172 115 331 P0C6B8 8.55e-47 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 47955 XM_029344511.2 150 24 172 115 331 P0C6B8 1.44e-46 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 47956 XM_029344511.2 150 24 172 115 331 P0C6B8 1.65e-46 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 47957 XM_029344511.2 150 24 172 115 331 P0C6B8 2.65e-41 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 47958 XM_029344511.2 150 24 172 115 331 P0C6B8 4.72e-38 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 47959 XM_029344511.2 150 24 172 115 331 P0C6B8 5.21e-37 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 47960 XM_029344511.2 150 24 172 115 331 P0C6B8 2.76e-34 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 47961 XM_029344511.2 150 24 172 115 331 P0C6B8 7.22e-31 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 47962 XM_029327173.2 258 244 136 125 25 O54853 1.15e-103 Potassium voltage-gated channel subfamily H member 6 (Ether-a-go-go-related gene potassium channel 2) (ERG-2) (Eag-related protein 2) (Ether-a-go-go-related protein 2) (Voltage-gated potassium channel subunit Kv11.2) Rattus norvegicus (Rat) membrane repolarization during action potential [GO:0086011]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307] GO:0005242; GO:0005249; GO:0005267; GO:0005886; GO:0006813; GO:0034765; GO:0042391; GO:0044877; GO:0060307; GO:0071805; GO:0086011; GO:0086091 47963 XM_029328925.2 42 49 49 28 21 P24044 9.86e-24 Calmodulin Plasmodium falciparum NA GO:0005509; GO:0005737; GO:0020007 47964 XM_044313300.1 19 3 5 7 1 NA NA NA NA NA NA 47965 XM_044310218.1 11 0 8 0 89 NA NA NA NA NA NA 47966 XM_029341493.2 964 764 654 1004 907 Q8WNW2 1.11e-89 G1/S-specific cyclin-D2 Sus scrofa (Pig) adult locomotory behavior [GO:0008344]; cell division [GO:0051301]; cellular response to X-ray [GO:0071481]; long-term memory [GO:0007616]; mitotic cell cycle phase transition [GO:0044772]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079] GO:0000079; GO:0000307; GO:0000785; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0007616; GO:0008284; GO:0008344; GO:0016538; GO:0019901; GO:0031965; GO:0043066; GO:0044772; GO:0045737; GO:0051301; GO:0071481; GO:0097129; GO:1900087 47967 XM_044308724.1 9 0 14 6 2 NA NA NA NA NA NA 47968 XR_003826733.2 0 0 21 0 20 NA NA NA NA NA NA 47969 XM_029331216.2 79 44 17 18 31 Q5VVH5 2.02e-52 Interleukin-1 receptor-associated kinase 1-binding protein 1 (IRAK1-binding protein 1) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; immune response [GO:0006955] GO:0005634; GO:0005737; GO:0006955; GO:0007249 47970 XM_044306816.1 239 0 0 74 0 P98070 5.36e-21 Bone morphogenetic protein 1 (BMP-1) (EC 3.4.24.-) Xenopus laevis (African clawed frog) cartilage development [GO:0051216]; cell differentiation [GO:0030154]; ossification [GO:0001503]; proteolysis [GO:0006508] GO:0001503; GO:0004222; GO:0005125; GO:0005509; GO:0005615; GO:0005794; GO:0006508; GO:0008083; GO:0008270; GO:0030154; GO:0051216 47971 XM_044327174.1 0 0 4 0 6 NA NA NA NA NA NA 47972 XM_029331833.2 3746 2437 1545 2776 3210 B5DF89 0 Cullin-3 Rattus norvegicus (Rat) anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell migration [GO:0016477]; cell morphogenesis [GO:0000902]; cell projection organization [GO:0030030]; COPII vesicle coating [GO:0048208]; embryonic cleavage [GO:0040016]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibroblast apoptotic process [GO:0044346]; gastrulation [GO:0007369]; gene expression [GO:0010467]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; liver morphogenesis [GO:0072576]; mitotic cell cycle [GO:0000278]; mitotic metaphase plate congression [GO:0007080]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nuclear protein quality control by the ubiquitin-proteasome system [GO:0071630]; positive regulation of cytokinesis [GO:0032467]; positive regulation of mitotic cell cycle phase transition [GO:1901992]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; positive regulation of protein ubiquitination [GO:0031398]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein destabilization [GO:0031648]; protein K48-linked ubiquitination [GO:0070936]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation protein catabolic process at postsynapse [GO:0140252]; stem cell division [GO:0017145]; stress fiber assembly [GO:0043149]; trophectodermal cellular morphogenesis [GO:0001831]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt signaling pathway [GO:0016055] GO:0000122; GO:0000209; GO:0000278; GO:0000902; GO:0000922; GO:0001701; GO:0001831; GO:0005112; GO:0005634; GO:0005737; GO:0005794; GO:0005813; GO:0005827; GO:0005886; GO:0006357; GO:0006511; GO:0006513; GO:0006888; GO:0006954; GO:0007080; GO:0007229; GO:0007369; GO:0010467; GO:0016055; GO:0016477; GO:0016567; GO:0017145; GO:0030030; GO:0030163; GO:0030332; GO:0031145; GO:0031208; GO:0031398; GO:0031461; GO:0031463; GO:0031625; GO:0031648; GO:0032467; GO:0035024; GO:0036126; GO:0040016; GO:0042802; GO:0043149; GO:0043161; GO:0044346; GO:0045202; GO:0045842; GO:0048208; GO:0051865; GO:0061630; GO:0070936; GO:0071630; GO:0072576; GO:0072686; GO:0098794; GO:0098978; GO:0140252; GO:1901992 47973 XM_044319031.1 269 128 142 430 429 Q76KP1 2.86e-55 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Homo sapiens (Human) NA GO:0008376; GO:0032580; GO:0033842 47974 XM_044319031.1 269 128 142 430 429 Q76KP1 1.6e-22 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Homo sapiens (Human) NA GO:0008376; GO:0032580; GO:0033842 47975 XM_044320929.1 72 9 21 16 218 Q9VBW3 5.55e-63 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 47976 XM_044320388.1 0 1 0 52 97 Q3UTQ8 2.3e-154 Cyclin-dependent kinase-like 5 (EC 2.7.11.22) Mus musculus (Mouse) modulation of chemical synaptic transmission [GO:0050804]; neuron migration [GO:0001764]; positive regulation of axon extension [GO:0045773]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of GTPase activity [GO:0043547]; protein autophosphorylation [GO:0046777]; protein localization to nucleus [GO:0034504]; protein phosphorylation [GO:0006468]; regulation of cilium assembly [GO:1902017]; regulation of dendrite development [GO:0050773]; regulation of postsynapse organization [GO:0099175] GO:0001764; GO:0004672; GO:0004693; GO:0005524; GO:0005634; GO:0005654; GO:0005813; GO:0006468; GO:0016301; GO:0031267; GO:0032587; GO:0032839; GO:0034504; GO:0036064; GO:0043547; GO:0044294; GO:0045202; GO:0045773; GO:0046777; GO:0048471; GO:0050773; GO:0050775; GO:0050804; GO:0060999; GO:0097542; GO:0098978; GO:0099092; GO:0099175; GO:0106310; GO:1902017 47977 XM_029336706.2 37 140 11 13 51 NA NA NA NA NA NA 47978 XM_029356942.2 606 316 292 312 447 NA NA NA NA NA NA 47979 XM_044317617.1 0 86 0 0 143 NA NA NA NA NA NA 47980 XM_044313208.1 84 88 0 41 68 Q90511 4.06e-144 Translation initiation factor eIF-2B subunit beta (S20I15) (eIF-2B GDP-GTP exchange factor subunit beta) Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) central nervous system development [GO:0007417]; myelination [GO:0042552]; oligodendrocyte development [GO:0014003]; T cell receptor signaling pathway [GO:0050852]; translational initiation [GO:0006413] GO:0003743; GO:0005524; GO:0005525; GO:0005737; GO:0005851; GO:0006413; GO:0007417; GO:0014003; GO:0042552; GO:0050852 47981 XM_044320908.1 55 173 57 14 74 Q3ZBV2 5.45e-136 ATP-dependent RNA helicase DDX19A (EC 3.6.4.13) (DEAD box protein 19A) Bos taurus (Bovine) poly(A)+ mRNA export from nucleus [GO:0016973] GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005654; GO:0010494; GO:0016887; GO:0016973 47982 XM_029333915.2 859 200 366 589 780 Q09499 0 Serine/threonine-protein kinase/endoribonuclease ire-1 (Inositol-requiring protein 2) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)] Caenorhabditis elegans endoplasmic reticulum unfolded protein response [GO:0030968]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; IRE1-mediated unfolded protein response [GO:0036498]; mRNA cleavage involved in mRNA processing [GO:0098787]; nematode larval development [GO:0002119]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response [GO:0006990]; protein phosphorylation [GO:0006468]; response to endoplasmic reticulum stress [GO:0034976]; response to hypoxia [GO:0001666]; response to topologically incorrect protein [GO:0035966] GO:0001666; GO:0002119; GO:0004521; GO:0004674; GO:0005524; GO:0005789; GO:0006468; GO:0006990; GO:0030968; GO:0034976; GO:0035966; GO:0036498; GO:0051082; GO:0070059; GO:0090305; GO:0098787; GO:0106310; GO:1990440; GO:1990604 47983 XM_044311670.1 10 0 2 7 0 B8VIU6 2.09e-51 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 47984 XR_006392300.1 28 39 13 1052 459 NA NA NA NA NA NA 47985 XM_029333275.2 11364 11351 6020 7444 7605 Q4R5P1 4.28e-114 Ras-related protein Rab-8A (EC 3.6.5.2) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) autophagy [GO:0006914]; axonogenesis [GO:0007409]; cellular response to insulin stimulus [GO:0032869]; cilium assembly [GO:0060271]; Golgi organization [GO:0007030]; protein localization to cilium [GO:0061512]; protein localization to plasma membrane [GO:0072659]; protein transport [GO:0015031]; regulation of autophagy [GO:0010506] GO:0003924; GO:0005525; GO:0005794; GO:0005813; GO:0005814; GO:0005886; GO:0005929; GO:0006914; GO:0007030; GO:0007409; GO:0010506; GO:0015031; GO:0019003; GO:0030496; GO:0030670; GO:0031267; GO:0032869; GO:0036064; GO:0045335; GO:0055038; GO:0060271; GO:0061512; GO:0072659 47986 XR_006396564.1 286 573 570 608 173 NA NA NA NA NA NA 47987 XM_044318725.1 7 0 0 0 65 NA NA NA NA NA NA 47988 XM_044327641.1 0 0 0 0 317 Q0P5W1 0 Vacuolar protein sorting-associated protein 8 homolog Mus musculus (Mouse) endosomal vesicle fusion [GO:0034058]; protein targeting to vacuole [GO:0006623] GO:0005769; GO:0006623; GO:0033263; GO:0034058; GO:0046872 47989 XM_044314375.1 29 0 5 7 141 Q9VBW3 5.09e-67 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 47990 XR_006393538.1 2 5 14 7 21 Q15485 2.6e-77 Ficolin-2 (37 kDa elastin-binding protein) (Collagen/fibrinogen domain-containing protein 2) (EBP-37) (Ficolin-B) (Ficolin-beta) (Hucolin) (L-ficolin) (Serum lectin p35) Homo sapiens (Human) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; positive regulation of opsonization [GO:1903028]; proteolysis [GO:0006508]; recognition of apoptotic cell [GO:0043654] GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005576; GO:0005581; GO:0005615; GO:0006508; GO:0008228; GO:0009897; GO:0042802; GO:0043394; GO:0043654; GO:0046872; GO:0048306; GO:0050829; GO:0050830; GO:0062023; GO:0070062; GO:0072562; GO:0097367; GO:1903028; GO:1905370; GO:2001065 47991 XM_044310516.1 1122 299 264 547 1001 NA NA NA NA NA NA 47992 XM_029343221.2 100 0 181 0 36 NA NA NA NA NA NA 47993 XM_044313126.1 5228 4008 3527 6305 5378 O74212 7e-154 Acyl-lipid (8-3)-desaturase (EC 1.14.19.30) (Delta(5) fatty acid desaturase) (Delta-5 fatty acid desaturase) Mortierella alpina (Oleaginous fungus) (Mortierella renispora) fatty acid biosynthetic process [GO:0006633] GO:0006633; GO:0016020; GO:0020037; GO:0046872; GO:0102866 47994 XM_044311736.1 264 85 45 133 50 Q80XJ3 1.49e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 47995 XM_029334063.2 31 16 31 79 55 D0E0C2 0 Sodium channel protein PaFPC1 (PaFPC1) (NavPaS) Periplaneta americana (American cockroach) (Blatta americana) regulation of ion transmembrane transport [GO:0034765] GO:0001518; GO:0005244; GO:0005248; GO:0034765 47996 XM_029341046.2 19 8 0 46 54 Q3V0J4 3.08e-28 Ankyrin repeat domain-containing protein 53 Mus musculus (Mouse) cell division [GO:0051301]; mitotic metaphase plate congression [GO:0007080]; positive regulation of microtubule polymerization [GO:0031116]; regulation of mitotic cytokinesis [GO:1902412]; regulation of mitotic spindle organization [GO:0060236] GO:0000922; GO:0005737; GO:0005819; GO:0007080; GO:0031116; GO:0051301; GO:0060236; GO:1902412 47997 XR_006395705.1 19 46 23 33 29 NA NA NA NA NA NA 47998 XM_044308092.1 1383 1315 699 1048 1004 P70627 1.27e-171 Glutamate carboxypeptidase 2 (EC 3.4.17.21) (Folate hydrolase 1) (Folylpoly-gamma-glutamate carboxypeptidase) (FGCP) (Glutamate carboxypeptidase II) (GCPII) (Membrane glutamate carboxypeptidase) (mGCP) (N-acetylated-alpha-linked acidic dipeptidase I) (NAALADase I) (Prostate-specific membrane antigen homolog) (Pteroylpoly-gamma-glutamate carboxypeptidase) Rattus norvegicus (Rat) C-terminal protein deglutamylation [GO:0035609]; folic acid-containing compound metabolic process [GO:0006760]; positive regulation of apoptotic process [GO:0043065]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508] GO:0004180; GO:0004181; GO:0005886; GO:0006508; GO:0006760; GO:0008233; GO:0009986; GO:0016020; GO:0016805; GO:0030163; GO:0035609; GO:0043065; GO:0046872; GO:1904492; GO:1904493 47999 XM_044321227.1 22 20 13 21 125 NA NA NA NA NA NA 48000 XM_029340672.2 1076 1686 1000 1357 965 Q9CQ46 3.71e-72 Dynein regulatory complex protein 8 (EF-hand calcium-binding domain-containing protein 2) Mus musculus (Mouse) NA GO:0005509; GO:0005737; GO:0005856; GO:0097228 48001 XR_006397681.1 100 77 63 104 157 NA NA NA NA NA NA 48002 XM_044321663.1 31 129 32 50 89 Q7RTR2 7.2e-53 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 48003 XM_029329816.2 79 0 0 39 233 Q9EQJ0 6.38e-162 Two pore calcium channel protein 1 (Voltage-dependent calcium channel protein TPC1) Mus musculus (Mouse) endocytosis involved in viral entry into host cell [GO:0075509]; positive regulation of autophagy [GO:0010508]; regulation of ion transmembrane transport [GO:0034765]; sodium ion transmembrane transport [GO:0035725] GO:0005244; GO:0005248; GO:0005765; GO:0010008; GO:0010508; GO:0015280; GO:0016020; GO:0019905; GO:0031901; GO:0034765; GO:0035725; GO:0036019; GO:0042802; GO:0042803; GO:0055038; GO:0072345; GO:0075509; GO:0080025; GO:0097682 48004 XM_044310230.1 8 3 10 24 0 NA NA NA NA NA NA 48005 XM_044318608.1 0 33 19 0 0 NA NA NA NA NA NA 48006 XM_044315756.1 20 16 15 19 9 NA NA NA NA NA NA 48007 XM_029339730.2 0 25 0 25 16 G1TFM5 2.51e-132 NA NA NA NA 48008 XM_029347526.2 6 15 31 17 41 NA NA NA NA NA NA 48009 XM_044324846.1 0 0 0 0 16 NA NA NA NA NA NA 48010 XM_029339589.2 897 891 536 663 955 NA NA NA NA NA NA 48011 XM_029323665.2 0 13 38 63 81 Q2KIA4 5.46e-116 Stearoyl-CoA desaturase 5 (EC 1.14.19.1) (Acyl-CoA-desaturase 4) (Stearoyl-CoA 9-desaturase) Bos taurus (Bovine) monounsaturated fatty acid biosynthetic process [GO:1903966]; unsaturated fatty acid biosynthetic process [GO:0006636] GO:0004768; GO:0005506; GO:0005789; GO:0006636; GO:0016491; GO:1903966 48012 XM_044314700.1 90 4 153 74 54 NA NA NA NA NA NA 48013 XM_029325535.2 991 380 592 1063 996 Q92576 7.77e-85 PHD finger protein 3 Homo sapiens (Human) DNA-templated transcription [GO:0006351] GO:0005634; GO:0006351; GO:0046872 48014 XM_044307849.1 180 136 0 144 153 Q2KJG3 0 Asparagine--tRNA ligase, cytoplasmic (EC 6.1.1.22) (Asparaginyl-tRNA synthetase) (AsnRS) Bos taurus (Bovine) asparaginyl-tRNA aminoacylation [GO:0006421] GO:0003676; GO:0004816; GO:0005524; GO:0005737; GO:0006421; GO:0031090 48015 XM_029348646.2 0 0 0 0 8 NA NA NA NA NA NA 48016 XM_044312786.1 714 647 341 682 829 Q08CI4 1.49e-134 Cyclin-Y-like protein 1 Danio rerio (Zebrafish) (Brachydanio rerio) regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of protein kinase activity [GO:0045859] GO:0000079; GO:0005886; GO:0019901; GO:0045859; GO:0060828; GO:0061575 48017 XR_006394899.1 16 43 6 0 8 NA NA NA NA NA NA 48018 XM_044315342.1 0 27 25 14 0 NA NA NA NA NA NA 48019 XM_044320484.1 2590 3078 1324 8463 5730 P16092 2.7e-97 Fibroblast growth factor receptor 1 (FGFR-1) (bFGF-R-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (MFR) (Proto-oncogene c-Fgr) (CD antigen CD331) Mus musculus (Mouse) angiogenesis [GO:0001525]; auditory receptor cell development [GO:0060117]; blood vessel morphogenesis [GO:0048514]; brain development [GO:0007420]; branching involved in salivary gland morphogenesis [GO:0060445]; calcium ion homeostasis [GO:0055074]; cardiac muscle cell proliferation [GO:0060038]; cell maturation [GO:0048469]; cell population proliferation [GO:0008283]; cementum mineralization [GO:0071529]; central nervous system neuron development [GO:0021954]; chondrocyte differentiation [GO:0002062]; diphosphate metabolic process [GO:0071344]; ear development [GO:0043583]; embryonic limb morphogenesis [GO:0030326]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; gene expression [GO:0010467]; generation of neurons [GO:0048699]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; lung development [GO:0030324]; lung-associated mesenchyme development [GO:0060484]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell proliferation [GO:0010463]; midbrain development [GO:0030901]; middle ear morphogenesis [GO:0042474]; motogenic signaling involved in postnatal olfactory bulb interneuron migration [GO:0021837]; negative regulation of fibroblast growth factor production [GO:0090272]; negative regulation of gene expression [GO:0010629]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron projection development [GO:0031175]; orbitofrontal cortex development [GO:0021769]; organ induction [GO:0001759]; outer ear morphogenesis [GO:0042473]; paraxial mesoderm development [GO:0048339]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of hepatic stellate cell activation [GO:2000491]; positive regulation of inflammatory response [GO:0050729]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway [GO:0090080]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of mitotic cell cycle DNA replication [GO:1903465]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neuron projection development [GO:0010976]; positive regulation of parathyroid hormone secretion [GO:2000830]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; protein autophosphorylation [GO:0046777]; regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling [GO:0060665]; regulation of cell population proliferation [GO:0042127]; regulation of epithelial cell proliferation [GO:0050678]; regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001239]; regulation of gene expression [GO:0010468]; regulation of lateral mesodermal cell fate specification [GO:0048378]; regulation of phosphate transport [GO:0010966]; regulation of phosphorus metabolic process [GO:0051174]; regulation of sensory perception of pain [GO:0051930]; regulation of stem cell proliferation [GO:0072091]; response to sodium phosphate [GO:1904383]; salivary gland morphogenesis [GO:0007435]; sensory perception of sound [GO:0007605]; stem cell differentiation [GO:0048863]; stem cell population maintenance [GO:0019827]; stem cell proliferation [GO:0072089]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; vasculogenesis involved in coronary vascular morphogenesis [GO:0060979]; ventricular zone neuroblast division [GO:0021847]; vitamin D3 metabolic process [GO:0070640] GO:0000122; GO:0001525; GO:0001657; GO:0001701; GO:0001759; GO:0001837; GO:0002053; GO:0002062; GO:0004713; GO:0004714; GO:0005007; GO:0005102; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0007169; GO:0007420; GO:0007435; GO:0007605; GO:0008201; GO:0008283; GO:0008284; GO:0008543; GO:0010463; GO:0010467; GO:0010468; GO:0010629; GO:0010763; GO:0010863; GO:0010966; GO:0010976; GO:0017134; GO:0018108; GO:0019827; GO:0021769; GO:0021837; GO:0021847; GO:0021954; GO:0030324; GO:0030326; GO:0030901; GO:0031175; GO:0031410; GO:0033674; GO:0035607; GO:0042127; GO:0042169; GO:0042472; GO:0042473; GO:0042474; GO:0042802; GO:0042803; GO:0043235; GO:0043406; GO:0043410; GO:0043536; GO:0043583; GO:0044877; GO:0045597; GO:0045666; GO:0045668; GO:0045787; GO:0045944; GO:0046777; GO:0048339; GO:0048378; GO:0048469; GO:0048471; GO:0048514; GO:0048699; GO:0048762; GO:0048863; GO:0050678; GO:0050729; GO:0050839; GO:0051174; GO:0051897; GO:0051930; GO:0055074; GO:0060038; GO:0060045; GO:0060117; GO:0060445; GO:0060484; GO:0060665; GO:0060979; GO:0070640; GO:0071344; GO:0071529; GO:0072089; GO:0072091; GO:0090080; GO:0090272; GO:0090722; GO:1903465; GO:1904383; GO:1905564; GO:2000491; GO:2000546; GO:2000648; GO:2000830; GO:2001239 48020 XM_029343540.2 1262 870 794 612 892 Q9DBT3 1.83e-38 Coiled-coil domain-containing protein 97 Mus musculus (Mouse) NA NA 48021 XM_044318839.1 714 351 276 805 734 Q86VH2 0 Kinesin-like protein KIF27 Homo sapiens (Human) cilium assembly [GO:0060271]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; microtubule-based movement [GO:0007018]; ventricular system development [GO:0021591] GO:0003351; GO:0003777; GO:0005524; GO:0005576; GO:0005737; GO:0005871; GO:0005874; GO:0005929; GO:0007018; GO:0008017; GO:0016887; GO:0021591; GO:0051649; GO:0060271 48022 XM_029333471.2 72 0 118 0 59 NA NA NA NA NA NA 48023 XM_029341001.2 49 59 65 75 48 NA NA NA NA NA NA 48024 XM_029330632.2 538 424 376 436 337 Q0VC84 5.82e-90 Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 (EC 2.4.1.122) (Core 1 O-glycan T-synthase) (Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1) (Core 1 beta1,3-galactosyltransferase 1) (C1GalT1) (Core 1 beta3-Gal-T1) Bos taurus (Bovine) angiogenesis [GO:0001525]; intestinal epithelial cell development [GO:0060576]; kidney development [GO:0001822]; O-glycan processing, core 1 [GO:0016267] GO:0001525; GO:0001822; GO:0016020; GO:0016263; GO:0016267; GO:0046872; GO:0060576 48025 XM_029324219.2 46 63 118 161 24 P0DXC0 4.95e-109 NA NA NA NA 48026 XM_044326597.1 318 157 108 319 148 NA NA NA NA NA NA 48027 XM_029344105.2 61 64 115 55 35 P12263 4.89e-21 Coagulation factor VIII (Procoagulant component) Sus scrofa (Pig) acute-phase response [GO:0006953]; blood coagulation [GO:0007596] GO:0005507; GO:0005615; GO:0006953; GO:0007596; GO:0016491 48028 XM_044315135.1 2711 670 13 758 8 NA NA NA NA NA NA 48029 XM_029339956.2 58 408 137 313 130 NA NA NA NA NA NA 48030 XM_029335254.2 232 189 64 223 236 NA NA NA NA NA NA 48031 XM_044317871.1 0 0 0 10 7 Q8CG08 2.72e-42 Collagen triple helix repeat-containing protein 1 Rattus norvegicus (Rat) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005581; GO:0005615; GO:0005737; GO:0016477; GO:0016528; GO:0017147; GO:0031012; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0090090; GO:0090103; GO:0090177 48032 XM_029332307.2 121 41 47 81 18 NA NA NA NA NA NA 48033 XR_006393137.1 0 225 0 760 0 NA NA NA NA NA NA 48034 XM_029341951.2 144 49 90 121 0 P36915 1.2e-164 Guanine nucleotide-binding protein-like 1 (GTP-binding protein HSR1) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; signal transduction [GO:0007165]; T cell mediated immunity [GO:0002456] GO:0002456; GO:0003924; GO:0005198; GO:0005525; GO:0005615; GO:0005634; GO:0006974; GO:0007165 48035 XM_029356238.2 3 6 1 3 0 Q86AW9 7.12e-143 Guanine deaminase (Guanase) (Guanine aminase) (EC 3.5.4.3) (Guanine aminohydrolase) (GAH) Dictyostelium discoideum (Social amoeba) guanine catabolic process [GO:0006147]; guanine metabolic process [GO:0046098] GO:0005829; GO:0006147; GO:0008270; GO:0008892; GO:0019239; GO:0046098 48036 XR_006392178.1 19 7 7 7 25 NA NA NA NA NA NA 48037 XM_044318774.1 650 1512 826 415 1168 Q60803 2.12e-102 TNF receptor-associated factor 3 (EC 2.3.2.27) (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (RING-type E3 ubiquitin transferase TRAF3) Mus musculus (Mouse) apoptotic process [GO:0006915]; innate immune response [GO:0045087]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of JNK cascade [GO:0046330]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of cytokine production [GO:0001817]; regulation of defense response to virus [GO:0050688]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of interferon-beta production [GO:0032648]; regulation of proteolysis [GO:0030162]; Toll signaling pathway [GO:0008063]; toll-like receptor signaling pathway [GO:0002224]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0001817; GO:0002224; GO:0005164; GO:0005739; GO:0005768; GO:0006915; GO:0008063; GO:0008270; GO:0009898; GO:0016740; GO:0019901; GO:0019903; GO:0030162; GO:0031625; GO:0031996; GO:0032088; GO:0032648; GO:0033209; GO:0035631; GO:0042802; GO:0042981; GO:0043122; GO:0045087; GO:0046330; GO:0050688; GO:0070534 48038 XM_029323853.2 19 8 8 17 36 Q566X8 1.69e-23 Diencephalon/mesencephalon homeobox protein 1-B Danio rerio (Zebrafish) (Brachydanio rerio) midbrain development [GO:0030901]; regulation of cell cycle [GO:0051726]; regulation of mitotic cell cycle [GO:0007346]; regulation of neural retina development [GO:0061074]; regulation of neurogenesis [GO:0050767]; regulation of transcription by RNA polymerase II [GO:0006357]; retina development in camera-type eye [GO:0060041] GO:0000977; GO:0000981; GO:0005634; GO:0006357; GO:0007346; GO:0030901; GO:0050767; GO:0051726; GO:0060041; GO:0061074 48039 XM_029330426.2 0 0 2 9 24 NA NA NA NA NA NA 48040 XM_044312505.1 8 6 24 2 24 NA NA NA NA NA NA 48041 XM_044310259.1 33 25 32 3 64 NA NA NA NA NA NA 48042 XM_029348359.2 46 22 33 20 3 NA NA NA NA NA NA 48043 XM_029347802.2 4102 3444 2450 3224 2662 Q14919 1.03e-43 Dr1-associated corepressor (Dr1-associated protein 1) (Negative cofactor 2-alpha) (NC2-alpha) Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; transcription by RNA polymerase II [GO:0006366] GO:0000122; GO:0001046; GO:0001091; GO:0003713; GO:0003714; GO:0005634; GO:0006355; GO:0006366; GO:0016251; GO:0017025; GO:0017054; GO:0042802; GO:0045944; GO:0046982; GO:0090575 48044 XM_029343236.2 182 81 264 624 178 P53992 0 Protein transport protein Sec24C (SEC24-related protein C) Homo sapiens (Human) COPII-coated vesicle cargo loading [GO:0090110]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; in utero embryonic development [GO:0001701]; intracellular protein transport [GO:0006886] GO:0000149; GO:0001701; GO:0005789; GO:0005829; GO:0006886; GO:0006888; GO:0008270; GO:0012507; GO:0030127; GO:0070971; GO:0090110 48045 XM_029329532.2 305 232 116 177 172 NA NA NA NA NA NA 48046 XM_044309915.1 30 4 35 5 119 NA NA NA NA NA NA 48047 XM_044328688.1 897 915 624 3311 1797 P16065 0 Speract receptor (EC 4.6.1.2) (Guanylate cyclase) Strongylocentrotus purpuratus (Purple sea urchin) cGMP biosynthetic process [GO:0006182]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]; receptor guanylyl cyclase signaling pathway [GO:0007168]; signal transduction [GO:0007165] GO:0001653; GO:0004383; GO:0004672; GO:0005524; GO:0005525; GO:0005886; GO:0006182; GO:0006468; GO:0007165; GO:0007168; GO:0035556 48048 XM_029330432.2 36 3 12 3 15 G5EDU6 2.5e-45 Transcription factor ovo-like homolog lin-48 (Abnormal cell lineage protein 48) Caenorhabditis elegans epidermal cell differentiation [GO:0009913]; hindgut morphogenesis [GO:0007442]; nematode male tail tip morphogenesis [GO:0045138]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0003700; GO:0005634; GO:0006355; GO:0006357; GO:0007442; GO:0009913; GO:0045138; GO:0046872 48049 XM_044311826.1 15 4 3 1 40 NA NA NA NA NA NA 48050 XM_044312877.1 1066 339 379 843 0 NA NA NA NA NA NA 48051 XM_044313010.1 0 0 0 37 0 NA NA NA NA NA NA 48052 XM_044319869.1 30 19 7 25 16 NA NA NA NA NA NA 48053 XM_044312753.1 441 314 237 529 568 Q8K4L3 3.73e-168 Supervillin (Archvillin) (p205/p250) Mus musculus (Mouse) actin filament severing [GO:0051014]; actin polymerization or depolymerization [GO:0008154]; barbed-end actin filament capping [GO:0051016]; positive regulation of cytokinesis [GO:0032467]; skeletal muscle tissue development [GO:0007519] GO:0002102; GO:0005546; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0007519; GO:0008154; GO:0015629; GO:0030496; GO:0032154; GO:0032467; GO:0036449; GO:0042995; GO:0043034; GO:0051014; GO:0051015; GO:0051016; GO:0070161 48054 XM_044318364.1 0 15 2 10 2 NA NA NA NA NA NA 48055 XM_044323314.1 1323 949 963 899 321 NA NA NA NA NA NA 48056 XM_029335197.2 1562 666 647 1062 1125 Q4R3G4 2.69e-42 RING finger protein 17 Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) cell differentiation [GO:0030154]; spermatogenesis [GO:0007283] GO:0005634; GO:0005737; GO:0007283; GO:0030154; GO:0046872 48057 XM_029335197.2 1562 666 647 1062 1125 Q4R3G4 2.4e-21 RING finger protein 17 Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) cell differentiation [GO:0030154]; spermatogenesis [GO:0007283] GO:0005634; GO:0005737; GO:0007283; GO:0030154; GO:0046872 48058 XR_006395135.1 237 55 125 85 155 NA NA NA NA NA NA 48059 XM_029353198.2 14 65 31 27 27 NA NA NA NA NA NA 48060 XM_029345354.2 240 240 213 379 227 NA NA NA NA NA NA 48061 XM_029337268.2 1453 327 213 956 221 Q8CG08 5.35e-43 Collagen triple helix repeat-containing protein 1 Rattus norvegicus (Rat) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005581; GO:0005615; GO:0005737; GO:0016477; GO:0016528; GO:0017147; GO:0031012; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0090090; GO:0090103; GO:0090177 48062 XM_044324134.1 54 26 25 10 12 NA NA NA NA NA NA 48063 XM_044319022.1 126 80 20 50 101 NA NA NA NA NA NA 48064 XM_029353644.2 0 1 4 7 48 NA NA NA NA NA NA 48065 XR_006391728.1 0 4 37 14 64 NA NA NA NA NA NA 48066 XR_003823391.2 903 299 217 132 311 NA NA NA NA NA NA 48067 XM_029343879.2 0 0 16 15 0 NA NA NA NA NA NA 48068 XM_029347088.2 9527 13737 5786 8132 6284 P61314 5.56e-108 60S ribosomal protein L15 Rattus norvegicus (Rat) cytoplasmic translation [GO:0002181]; response to ethanol [GO:0045471] GO:0002181; GO:0003723; GO:0003735; GO:0005634; GO:0022625; GO:0022626; GO:0031672; GO:0045202; GO:0045471 48069 XM_044322571.1 0 0 0 0 52 NA NA NA NA NA NA 48070 XM_029338578.2 2 13 163 1 3 NA NA NA NA NA NA 48071 XM_044316446.1 0 0 4 31 8 NA NA NA NA NA NA 48072 XM_044314287.1 265 125 336 424 342 A1KZ92 2.34e-30 Probable oxidoreductase PXDNL (EC 1.-.-.-) (Cardiac peroxidase) (Inactive peroxidasin-like protein) (Polysomal ribonuclease 1) (PRM1) (Vascular peroxidase 2) Homo sapiens (Human) hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979] GO:0004519; GO:0004601; GO:0005615; GO:0005783; GO:0005886; GO:0006979; GO:0020037; GO:0042744; GO:0046872; GO:0140825 48073 XM_044314287.1 265 125 336 424 342 A1KZ92 6.15e-21 Probable oxidoreductase PXDNL (EC 1.-.-.-) (Cardiac peroxidase) (Inactive peroxidasin-like protein) (Polysomal ribonuclease 1) (PRM1) (Vascular peroxidase 2) Homo sapiens (Human) hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979] GO:0004519; GO:0004601; GO:0005615; GO:0005783; GO:0005886; GO:0006979; GO:0020037; GO:0042744; GO:0046872; GO:0140825 48074 XM_029335424.2 272 323 126 316 441 NA NA NA NA NA NA 48075 XM_029335752.2 40 0 16 35 18 O43603 3.75e-21 Galanin receptor type 2 (GAL2-R) (GALR-2) Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell surface receptor signaling pathway [GO:0007166]; feeding behavior [GO:0007631]; galanin-activated signaling pathway [GO:0090663]; inositol phosphate metabolic process [GO:0043647]; learning or memory [GO:0007611]; muscle contraction [GO:0006936]; negative regulation of adenylate cyclase activity [GO:0007194]; neuron projection development [GO:0031175]; neuropeptide signaling pathway [GO:0007218]; phosphatidylinositol metabolic process [GO:0046488]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of large conductance calcium-activated potassium channel activity [GO:1902608]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0004966; GO:0005886; GO:0005929; GO:0006936; GO:0007166; GO:0007188; GO:0007189; GO:0007194; GO:0007200; GO:0007204; GO:0007218; GO:0007611; GO:0007631; GO:0008528; GO:0016020; GO:0017046; GO:0031175; GO:0042923; GO:0043647; GO:0045944; GO:0046488; GO:0090663; GO:1902608 48076 XM_029350959.2 854 718 501 518 720 Q08CI4 1.2e-134 Cyclin-Y-like protein 1 Danio rerio (Zebrafish) (Brachydanio rerio) regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of protein kinase activity [GO:0045859] GO:0000079; GO:0005886; GO:0019901; GO:0045859; GO:0060828; GO:0061575 48077 XM_044322782.1 0 0 6 0 0 Q94887 1.04e-29 Neurexin-4 (Neurexin IV) Drosophila melanogaster (Fruit fly) axon ensheathment [GO:0008366]; cell adhesion involved in heart morphogenesis [GO:0061343]; cell-cell junction organization [GO:0045216]; dorsal closure [GO:0007391]; establishment of glial blood-brain barrier [GO:0060857]; heart process [GO:0003015]; nerve maturation [GO:0021682]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]; synaptic target recognition [GO:0008039]; terminal button organization [GO:0072553] GO:0003015; GO:0005886; GO:0005919; GO:0007391; GO:0008039; GO:0008104; GO:0008366; GO:0019991; GO:0021682; GO:0035151; GO:0045202; GO:0045216; GO:0048786; GO:0060857; GO:0061343; GO:0072553; GO:0097105 48078 XM_044323713.1 3932 3133 2092 3455 3461 Q27433 2.71e-114 Mechanosensory protein 2 Caenorhabditis elegans detection of mechanical stimulus involved in sensory perception of touch [GO:0050976]; mechanosensory behavior [GO:0007638]; positive regulation of detection of mechanical stimulus involved in sensory perception of touch [GO:1905789]; positive regulation of mechanosensory behavior [GO:1905792]; potassium ion transport [GO:0006813]; response to mechanical stimulus [GO:0009612] GO:0005272; GO:0005886; GO:0006813; GO:0007638; GO:0009612; GO:0015485; GO:0032589; GO:0043005; GO:0050976; GO:1905789; GO:1905792 48079 XM_044315662.1 54 34 29 15 205 O43847 1.28e-114 Nardilysin (EC 3.4.24.61) (N-arginine dibasic convertase) (NRD convertase) (NRD-C) (Nardilysin convertase) Homo sapiens (Human) negative regulation of cold-induced thermogenesis [GO:0120163]; positive regulation of axonogenesis [GO:0050772]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of myelination [GO:0031643]; proteolysis [GO:0006508]; regulation of endopeptidase activity [GO:0052548] GO:0004222; GO:0005739; GO:0005829; GO:0006508; GO:0009986; GO:0030425; GO:0031643; GO:0046872; GO:0048408; GO:0050772; GO:0051044; GO:0052548; GO:0120163 48080 XR_003824164.2 0 0 0 0 14 NA NA NA NA NA NA 48081 XM_029335261.2 3 6 0 15 34 O70220 2e-33 Forkhead box protein Q1 (HFH-1l) (HNF-3/forkhead-like protein 1) (HFH-1) (Hepatocyte nuclear factor 3 forkhead homolog 1) Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; hair follicle morphogenesis [GO:0031069]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000978; GO:0000981; GO:0001227; GO:0005634; GO:0006357; GO:0009653; GO:0030154; GO:0031069; GO:0043524; GO:1990837 48082 XM_044322909.1 1353 1322 904 1521 1807 P41250 0 Glycine--tRNA ligase (EC 6.1.1.14) (Diadenosine tetraphosphate synthetase) (Ap4A synthetase) (EC 2.7.7.-) (Glycyl-tRNA synthetase) (GlyRS) (Glycyl-tRNA synthetase 1) Homo sapiens (Human) diadenosine tetraphosphate biosynthetic process [GO:0015966]; glycyl-tRNA aminoacylation [GO:0006426]; mitochondrial glycyl-tRNA aminoacylation [GO:0070150]; tRNA aminoacylation for protein translation [GO:0006418] GO:0004081; GO:0004820; GO:0005524; GO:0005737; GO:0005739; GO:0005759; GO:0005829; GO:0006418; GO:0006426; GO:0015966; GO:0016740; GO:0030141; GO:0030424; GO:0042802; GO:0046983; GO:0070062; GO:0070150 48083 XM_029327835.2 480 441 307 159 30 Q5ZL23 1.46e-66 Amyloid beta A4 precursor protein-binding family B member 1-interacting protein (APBB1-interacting protein 1) Gallus gallus (Chicken) signal transduction [GO:0007165] GO:0005829; GO:0005856; GO:0005886; GO:0007165 48084 XM_044322405.1 0 4 8 0 0 NA NA NA NA NA NA 48085 XM_044308027.1 1827 1461 1142 2640 2613 Q5R6J0 0 Proteasome adapter and scaffold protein ECM29 (Proteasome-associated protein ECM29 homolog) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) proteasome assembly [GO:0043248] GO:0000502; GO:0005634; GO:0005771; GO:0005783; GO:0005793; GO:0005815; GO:0030139; GO:0043248; GO:0060090 48086 XM_029327265.2 7 7 34 40 3 A4QNP7 3.83e-29 Doublesex- and mab-3-related transcription factor A2 (Doublesex- and mab-3-related transcription factor 5) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006355; GO:0043565; GO:0046872 48087 XM_029340922.2 670 302 255 530 889 Q9UBJ2 0 ATP-binding cassette sub-family D member 2 (EC 3.1.2.-) (EC 7.6.2.-) (Adrenoleukodystrophy-like 1) (Adrenoleukodystrophy-related protein) (hALDR) Homo sapiens (Human) fatty acid beta-oxidation [GO:0006635]; long-chain fatty acid import into peroxisome [GO:0015910]; myelin maintenance [GO:0043217]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection maintenance [GO:1990535]; peroxisome organization [GO:0007031]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of unsaturated fatty acid biosynthetic process [GO:2001280]; response to bacterium [GO:0009617]; very long-chain fatty acid catabolic process [GO:0042760]; very long-chain fatty acid metabolic process [GO:0000038] GO:0000038; GO:0005324; GO:0005524; GO:0005777; GO:0005778; GO:0005829; GO:0006635; GO:0007031; GO:0009617; GO:0015910; GO:0016887; GO:0032000; GO:0042626; GO:0042760; GO:0042803; GO:0043217; GO:0046982; GO:0047617; GO:0140359; GO:1900016; GO:1903427; GO:1990535; GO:2001280 48088 XR_006395910.1 42 67 41 10 71 NA NA NA NA NA NA 48089 XM_044308122.1 20 4 41 26 16 NA NA NA NA NA NA 48090 XM_029329764.2 5737 4575 4762 6754 5797 NA NA NA NA NA NA 48091 XM_044308006.1 4424 2717 1800 7300 3642 Q64487 0 Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48) Mus musculus (Mouse) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; neuron differentiation [GO:0030182]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse assembly [GO:0051965]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; regulation of immune response [GO:0050776]; regulation of postsynaptic density assembly [GO:0099151]; synaptic membrane adhesion [GO:0099560]; trans-synaptic signaling [GO:0099537]; trans-synaptic signaling by trans-synaptic complex [GO:0099545] GO:0004725; GO:0005102; GO:0006470; GO:0007157; GO:0030182; GO:0042734; GO:0046426; GO:0050775; GO:0050776; GO:0050804; GO:0050839; GO:0051965; GO:0097105; GO:0098685; GO:0098686; GO:0098978; GO:0099054; GO:0099151; GO:0099537; GO:0099545; GO:0099560 48092 XM_044308006.1 4424 2717 1800 7300 3642 Q64487 9.41e-68 Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48) Mus musculus (Mouse) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; neuron differentiation [GO:0030182]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse assembly [GO:0051965]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; regulation of immune response [GO:0050776]; regulation of postsynaptic density assembly [GO:0099151]; synaptic membrane adhesion [GO:0099560]; trans-synaptic signaling [GO:0099537]; trans-synaptic signaling by trans-synaptic complex [GO:0099545] GO:0004725; GO:0005102; GO:0006470; GO:0007157; GO:0030182; GO:0042734; GO:0046426; GO:0050775; GO:0050776; GO:0050804; GO:0050839; GO:0051965; GO:0097105; GO:0098685; GO:0098686; GO:0098978; GO:0099054; GO:0099151; GO:0099537; GO:0099545; GO:0099560 48093 XM_044308006.1 4424 2717 1800 7300 3642 Q64487 2.31e-55 Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48) Mus musculus (Mouse) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; neuron differentiation [GO:0030182]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse assembly [GO:0051965]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; regulation of immune response [GO:0050776]; regulation of postsynaptic density assembly [GO:0099151]; synaptic membrane adhesion [GO:0099560]; trans-synaptic signaling [GO:0099537]; trans-synaptic signaling by trans-synaptic complex [GO:0099545] GO:0004725; GO:0005102; GO:0006470; GO:0007157; GO:0030182; GO:0042734; GO:0046426; GO:0050775; GO:0050776; GO:0050804; GO:0050839; GO:0051965; GO:0097105; GO:0098685; GO:0098686; GO:0098978; GO:0099054; GO:0099151; GO:0099537; GO:0099545; GO:0099560 48094 XM_044308006.1 4424 2717 1800 7300 3642 Q64487 3.6e-27 Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48) Mus musculus (Mouse) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; neuron differentiation [GO:0030182]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse assembly [GO:0051965]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; regulation of immune response [GO:0050776]; regulation of postsynaptic density assembly [GO:0099151]; synaptic membrane adhesion [GO:0099560]; trans-synaptic signaling [GO:0099537]; trans-synaptic signaling by trans-synaptic complex [GO:0099545] GO:0004725; GO:0005102; GO:0006470; GO:0007157; GO:0030182; GO:0042734; GO:0046426; GO:0050775; GO:0050776; GO:0050804; GO:0050839; GO:0051965; GO:0097105; GO:0098685; GO:0098686; GO:0098978; GO:0099054; GO:0099151; GO:0099537; GO:0099545; GO:0099560 48095 XM_029353330.2 187 66 53 102 281 Q8BHJ9 0 Pre-mRNA-splicing factor SLU7 Mus musculus (Mouse) alternative mRNA splicing, via spliceosome [GO:0000380]; cellular response to heat [GO:0034605]; intracellular protein transport [GO:0006886]; mRNA 3'-splice site recognition [GO:0000389]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375] GO:0000375; GO:0000380; GO:0000386; GO:0000389; GO:0005634; GO:0005654; GO:0005681; GO:0005737; GO:0005829; GO:0006886; GO:0008270; GO:0008380; GO:0016607; GO:0030532; GO:0030628; GO:0034605; GO:0043231; GO:0071013 48096 XM_029350557.2 352 299 0 461 306 NA NA NA NA NA NA 48097 XM_029346596.2 846 547 390 265 278 NA NA NA NA NA NA 48098 XR_006394731.1 168 94 335 126 772 NA NA NA NA NA NA 48099 XM_044307054.1 19 26 5 17 19 Q8K3Z0 5.68e-22 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 48100 XM_029334700.2 1393 988 819 1166 1210 Q9P2P5 0 E3 ubiquitin-protein ligase HECW2 (EC 2.3.2.26) (HECT, C2 and WW domain-containing protein 2) (HECT-type E3 ubiquitin transferase HECW2) (NEDD4-like E3 ubiquitin-protein ligase 2) Homo sapiens (Human) negative regulation of sodium ion transmembrane transporter activity [GO:2000650]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of dendrite morphogenesis [GO:0048814]; regulation of mitotic metaphase/anaphase transition [GO:0030071] GO:0000209; GO:0005737; GO:0016567; GO:0030071; GO:0043161; GO:0048814; GO:0061630; GO:0072686; GO:2000650 48101 XM_029334700.2 1393 988 819 1166 1210 Q9P2P5 1.86e-48 E3 ubiquitin-protein ligase HECW2 (EC 2.3.2.26) (HECT, C2 and WW domain-containing protein 2) (HECT-type E3 ubiquitin transferase HECW2) (NEDD4-like E3 ubiquitin-protein ligase 2) Homo sapiens (Human) negative regulation of sodium ion transmembrane transporter activity [GO:2000650]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of dendrite morphogenesis [GO:0048814]; regulation of mitotic metaphase/anaphase transition [GO:0030071] GO:0000209; GO:0005737; GO:0016567; GO:0030071; GO:0043161; GO:0048814; GO:0061630; GO:0072686; GO:2000650 48102 XM_044321195.1 78 108 143 92 137 A3KQV2 4.89e-26 BRO1 domain-containing protein BROX (BRO1 domain- and CAAX motif-containing protein) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0016020 48103 XM_029346713.2 579 0 775 0 416 P54965 2.84e-41 Conjugated bile acid hydrolase (CBAH) (EC 3.5.1.-) (Bile salt hydrolase) (BSH) (CBAH-1) (Choloylglycine hydrolase) (EC 3.5.1.24) Clostridium perfringens (strain 13 / Type A) bile acid biosynthetic process [GO:0006699] GO:0006699; GO:0045302; GO:0047742 48104 XR_006394633.1 984 774 481 704 630 Q6P832 3.37e-173 Glycine amidinotransferase, mitochondrial (EC 2.1.4.1) (L-arginine:glycine amidinotransferase) (Transamidinase) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) creatine biosynthetic process [GO:0006601] GO:0005743; GO:0006601; GO:0015068 48105 XM_029349140.2 113 74 17 496 17 O16025 0 Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (AOS) (EC 4.2.1.-) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)] Plexaura homomalla (Black sea rod) arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; lipid oxidation [GO:0034440]; oxylipin biosynthetic process [GO:0031408] GO:0005506; GO:0005737; GO:0006633; GO:0009978; GO:0016020; GO:0019369; GO:0020037; GO:0031408; GO:0034440; GO:0047677 48106 XM_029332841.2 1409 979 743 1208 1063 NA NA NA NA NA NA 48107 XM_044325988.1 4267 963 565 5026 4361 NA NA NA NA NA NA 48108 XR_006391809.1 5 8 0 0 0 NA NA NA NA NA NA 48109 XM_044326814.1 0 14 87 0 0 NA NA NA NA NA NA 48110 XM_029335365.2 0 73 117 77 9 P30884 3.99e-76 Bone morphogenetic protein 2-B (BMP-2-II) Xenopus laevis (African clawed frog) cartilage development [GO:0051216]; cell differentiation [GO:0030154]; ossification [GO:0001503] GO:0001503; GO:0005125; GO:0005615; GO:0008083; GO:0030154; GO:0051216 48111 XM_029325005.2 1633 905 533 1020 896 Q8BHJ5 0 F-box-like/WD repeat-containing protein TBL1XR1 (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1) (Transducin beta-like 1X-related protein 1) Mus musculus (Mouse) adipose tissue development [GO:0060612]; blastocyst hatching [GO:0001835]; chromatin organization [GO:0006325]; fat pad development [GO:0060613]; histone deacetylation [GO:0016575]; lipid catabolic process [GO:0016042]; multicellular organism growth [GO:0035264]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of gene expression [GO:0010468]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of triglyceride metabolic process [GO:0090207]; response to dietary excess [GO:0002021]; white fat cell differentiation [GO:0050872] GO:0000118; GO:0000122; GO:0000976; GO:0001835; GO:0002021; GO:0003677; GO:0003714; GO:0005634; GO:0005654; GO:0006325; GO:0006357; GO:0008013; GO:0010468; GO:0016042; GO:0016575; GO:0017053; GO:0035264; GO:0042393; GO:0043161; GO:0045892; GO:0045893; GO:0045944; GO:0047485; GO:0050872; GO:0060612; GO:0060613; GO:0072686; GO:0090207; GO:0090263 48112 XM_044315831.1 0 6 0 0 0 NA NA NA NA NA NA 48113 XR_006395734.1 0 0 0 36 0 Q2T9I5 1.35e-21 RNA-binding protein 26 (RNA-binding motif protein 26) Xenopus laevis (African clawed frog) mRNA processing [GO:0006397] GO:0003723; GO:0005634; GO:0006397; GO:0046872 48114 XM_029323555.2 396 244 171 435 267 NA NA NA NA NA NA 48115 XM_029339545.2 956 475 589 796 1041 A0JPP8 1.04e-72 Centrosomal protein CCDC61 (Coiled-coil domain-containing protein 61) (VFL3 homolog) Rattus norvegicus (Rat) cell projection organization [GO:0030030]; centriole assembly [GO:0098534]; mitotic spindle assembly [GO:0090307] GO:0005737; GO:0005813; GO:0005815; GO:0008017; GO:0030030; GO:0034451; GO:0036064; GO:0042802; GO:0090307; GO:0098534; GO:0120103 48116 XM_029331219.2 529 353 199 243 287 Q9TZM3 6.91e-130 Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1) (Leucine-rich repeats, ras-like domain, kinase protein 1) (PARK8-related kinase) Caenorhabditis elegans axon extension involved in axon guidance [GO:0048846]; negative regulation of neuron death [GO:1901215]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; response to endoplasmic reticulum stress [GO:0034976]; response to oxidative stress [GO:0006979]; synaptic vesicle transport [GO:0048489] GO:0004674; GO:0005524; GO:0005525; GO:0005737; GO:0005794; GO:0006468; GO:0006979; GO:0008104; GO:0034976; GO:0043025; GO:0046872; GO:0048489; GO:0048846; GO:0106310; GO:1901215 48117 XM_029331219.2 529 353 199 243 287 Q9TZM3 2.24e-78 Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1) (Leucine-rich repeats, ras-like domain, kinase protein 1) (PARK8-related kinase) Caenorhabditis elegans axon extension involved in axon guidance [GO:0048846]; negative regulation of neuron death [GO:1901215]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; response to endoplasmic reticulum stress [GO:0034976]; response to oxidative stress [GO:0006979]; synaptic vesicle transport [GO:0048489] GO:0004674; GO:0005524; GO:0005525; GO:0005737; GO:0005794; GO:0006468; GO:0006979; GO:0008104; GO:0034976; GO:0043025; GO:0046872; GO:0048489; GO:0048846; GO:0106310; GO:1901215 48118 XM_029335161.2 5958 6815 4796 6283 5307 Q8K3J1 8.54e-101 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (EC 7.1.1.2) (Complex I-23kD) (CI-23kD) (NADH-ubiquinone oxidoreductase 23 kDa subunit) Mus musculus (Mouse) aerobic respiration [GO:0009060]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrial respiratory chain complex I assembly [GO:0032981]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776]; response to oxidative stress [GO:0006979] GO:0003954; GO:0005739; GO:0005747; GO:0006120; GO:0006979; GO:0008137; GO:0009060; GO:0032981; GO:0042776; GO:0046872; GO:0051539 48119 XR_003824340.2 2339 1021 565 1928 530 NA NA NA NA NA NA 48120 XM_029349848.2 126 116 112 186 201 NA NA NA NA NA NA 48121 XM_029351974.2 17 0 0 43 37 NA NA NA NA NA NA 48122 XM_044315241.1 0 0 5 50 37 NA NA NA NA NA NA 48123 XR_003828330.2 566 295 162 310 345 NA NA NA NA NA NA 48124 XR_006395871.1 36 26 13 9 111 NA NA NA NA NA NA 48125 XM_029357358.2 3011 2781 2663 3853 4188 NA NA NA NA NA NA 48126 XM_029342866.2 0 0 0 18 0 NA NA NA NA NA NA 48127 XR_003825365.2 24 1 0 6 0 NA NA NA NA NA NA 48128 XM_044312362.1 203 146 143 148 233 Q8AVJ1 2.26e-38 Proline-rich protein 5 (Protein observed with Rictor-1) (Protor-1) Xenopus laevis (African clawed frog) NA NA 48129 XM_029335369.2 171 482 115 258 812 Q5QNQ6 5.89e-157 Oxysterol-binding protein 2 Mus musculus (Mouse) spermatid development [GO:0007286] GO:0005829; GO:0005886; GO:0007286; GO:0015248; GO:0015485; GO:0016020; GO:0032934; GO:0043231; GO:0097038; GO:0097440 48130 XM_029335369.2 171 482 115 258 812 Q5QNQ6 1.26e-33 Oxysterol-binding protein 2 Mus musculus (Mouse) spermatid development [GO:0007286] GO:0005829; GO:0005886; GO:0007286; GO:0015248; GO:0015485; GO:0016020; GO:0032934; GO:0043231; GO:0097038; GO:0097440 48131 XR_006392747.1 2 7 0 0 4 NA NA NA NA NA NA 48132 XM_029344282.2 392 133 688 163 2554 Q10944 1.29e-27 Putative acid phosphatase 5 (EC 3.1.3.2) Caenorhabditis elegans dephosphorylation [GO:0016311] GO:0003993; GO:0016311; GO:0016791 48133 XM_029341316.2 17 16 15 52 50 NA NA NA NA NA NA 48134 XM_029349490.2 3258 1951 1055 2121 1888 Q9MYP6 2.14e-87 17-beta-hydroxysteroid dehydrogenase 14 (17-beta-HSD 14) (EC 1.1.1.62) (17-beta-hydroxysteroid dehydrogenase DHRS10) (Dehydrogenase/reductase SDR family member 10) (Retinal short-chain dehydrogenase/reductase retSDR3) Bos taurus (Bovine) steroid catabolic process [GO:0006706] GO:0004303; GO:0005829; GO:0006706; GO:0042802; GO:0044594; GO:0047045 48135 XM_029325747.2 454 341 456 437 424 Q9XI87 2.14e-24 Serine/threonine-protein kinase VIK (EC 2.7.11.1) (VH1-interacting kinase) Arabidopsis thaliana (Mouse-ear cress) auxin-activated signaling pathway [GO:0009734]; brassinosteroid mediated signaling pathway [GO:0009742]; cellular response to glucose stimulus [GO:0071333]; leaf vascular tissue pattern formation [GO:0010305]; positive regulation of glucose transmembrane transport [GO:0010828]; protein phosphorylation [GO:0006468]; response to auxin [GO:0009733]; response to salt [GO:1902074] GO:0000325; GO:0004674; GO:0004709; GO:0004712; GO:0005524; GO:0005576; GO:0006468; GO:0009733; GO:0009734; GO:0009742; GO:0010305; GO:0010828; GO:0071333; GO:1902074 48136 XM_044313450.1 19 6 5 8 211 NA NA NA NA NA NA 48137 XM_029354409.2 193 149 112 132 191 Q94K49 9.45e-28 Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1 (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) epigenetic regulation of gene expression [GO:0040029] GO:0003682; GO:0004518; GO:0005634; GO:0035098; GO:0035102; GO:0040029; GO:0046872 48138 XM_029345238.2 737 546 384 769 521 NA NA NA NA NA NA 48139 XM_029343039.2 213 143 39 227 123 NA NA NA NA NA NA 48140 XM_044313042.1 157 0 113 0 115 NA NA NA NA NA NA 48141 XM_029349792.2 1101 593 647 804 952 NA NA NA NA NA NA 48142 XM_029334960.2 3207 4764 1662 2268 1833 B0BMZ6 2.2e-44 Cilia- and flagella-associated protein 119 (Coiled-coil domain-containing protein 189) (Spergen-4) Rattus norvegicus (Rat) NA GO:0001669; GO:0005737; GO:0097228 48143 XM_029340335.2 78 34 34 122 61 Q9Z0S2 3.04e-26 LIM/homeobox protein Lhx2 (Homeobox protein LH-2) (LIM homeobox protein 2) Mus musculus (Mouse) anatomical structure formation involved in morphogenesis [GO:0048646]; axon extension [GO:0048675]; axon guidance [GO:0007411]; brain development [GO:0007420]; cerebral cortex development [GO:0021987]; dorsal/ventral pattern formation [GO:0009953]; hair follicle development [GO:0001942]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; mesoderm development [GO:0007498]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of neurogenesis [GO:0050768]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; nervous system development [GO:0007399]; neural tube closure [GO:0001843]; neurogenesis [GO:0022008]; neuron differentiation [GO:0030182]; olfactory bulb development [GO:0021772]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; retina development in camera-type eye [GO:0060041]; telencephalon development [GO:0021537]; telencephalon regionalization [GO:0021978] GO:0000977; GO:0000978; GO:0000981; GO:0001228; GO:0001843; GO:0001942; GO:0003682; GO:0005634; GO:0005654; GO:0006357; GO:0007399; GO:0007411; GO:0007420; GO:0007498; GO:0009953; GO:0021537; GO:0021772; GO:0021978; GO:0021987; GO:0022008; GO:0030182; GO:0043565; GO:0045199; GO:0045814; GO:0045893; GO:0045944; GO:0046872; GO:0048646; GO:0048675; GO:0050768; GO:0060041; GO:2000179; GO:2000678 48144 XM_044318096.1 0 0 3 10 173 NA NA NA NA NA NA 48145 XM_044325156.1 734 355 177 486 438 NA NA NA NA NA NA 48146 XM_029342950.2 845 288 545 333 437 D3ZKF5 3.72e-88 Serine protease HTR4 (EC 3.4.21.-) (High-temperature requirement factor A4) Rattus norvegicus (Rat) positive regulation of apoptotic process [GO:0043065]; programmed cell death [GO:0012501]; proteolysis [GO:0006508] GO:0004175; GO:0004222; GO:0004252; GO:0005576; GO:0006508; GO:0012501; GO:0042802; GO:0043065 48147 XM_029342973.2 2992 2235 1792 3428 3538 Q9WVK7 3.8e-134 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HCDH) (EC 1.1.1.35) (Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase) (Short-chain 3-hydroxyacyl-CoA dehydrogenase) Rattus norvegicus (Rat) fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; regulation of insulin secretion [GO:0050796]; response to activity [GO:0014823]; response to hormone [GO:0009725]; response to insulin [GO:0032868]; response to xenobiotic stimulus [GO:0009410] GO:0003857; GO:0005654; GO:0005739; GO:0005759; GO:0006635; GO:0009410; GO:0009725; GO:0014823; GO:0032868; GO:0042802; GO:0046676; GO:0050796; GO:0070403; GO:0120162 48148 XM_029329198.2 783 1037 640 536 683 A5WUL3 1.67e-60 Mediator of RNA polymerase II transcription subunit 22 (Mediator complex subunit 22) (Surfeit locus protein 5) Danio rerio (Zebrafish) (Brachydanio rerio) regulation of transcription by RNA polymerase II [GO:0006357] GO:0003712; GO:0006357; GO:0016592 48149 XM_029345819.2 1892 1027 1102 1125 1082 Q63481 1.56e-70 Ras-related protein Rab-7L1 (Rab-7-like protein 1) (Ras-related protein Rab-29) Rattus norvegicus (Rat) cell differentiation [GO:0030154]; cilium assembly [GO:0060271]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886]; melanosome organization [GO:0032438]; mitochondrion organization [GO:0007005]; modulation by host of viral process [GO:0044788]; negative regulation of neuron projection development [GO:0010977]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of receptor recycling [GO:0001921]; positive regulation of T cell receptor signaling pathway [GO:0050862]; protein localization to ciliary membrane [GO:1903441]; protein localization to membrane [GO:0072657]; regulation of neuron death [GO:1901214]; regulation of retrograde transport, endosome to Golgi [GO:1905279]; response to bacterium [GO:0009617]; retrograde transport, endosome to Golgi [GO:0042147]; synapse assembly [GO:0007416]; T cell activation [GO:0042110]; toxin transport [GO:1901998]; viral RNA genome replication [GO:0039694] GO:0001921; GO:0003924; GO:0005525; GO:0005737; GO:0005739; GO:0005769; GO:0005773; GO:0005794; GO:0005801; GO:0005802; GO:0005829; GO:0005856; GO:0005886; GO:0006886; GO:0007005; GO:0007030; GO:0007416; GO:0009617; GO:0010977; GO:0012505; GO:0019003; GO:0019894; GO:0030154; GO:0031267; GO:0031982; GO:0032438; GO:0039694; GO:0042110; GO:0042147; GO:0042470; GO:0044788; GO:0048471; GO:0050862; GO:0055037; GO:0060271; GO:0070840; GO:0072657; GO:0090316; GO:0097708; GO:1901214; GO:1901998; GO:1903441; GO:1905279 48150 XM_044321601.1 0 23 0 0 39 O43822 2.51e-27 Cilia- and flagella-associated protein 410 (C21orf-HUMF09G8.5) (Leucine-rich repeat-containing protein 76) (YF5/A2) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; cilium assembly [GO:0060271]; cytoskeleton organization [GO:0007010]; regulation of cell shape [GO:0008360]; smoothened signaling pathway [GO:0007224] GO:0001750; GO:0005737; GO:0005739; GO:0005829; GO:0005886; GO:0006974; GO:0007010; GO:0007224; GO:0008360; GO:0032391; GO:0036064; GO:0043231; GO:0060271 48151 XM_029330397.2 673 686 444 639 585 Q9ES56 1.43e-102 Trafficking protein particle complex subunit 4 (Synbindin) (TRS23 homolog) Mus musculus (Mouse) autophagy [GO:0006914]; COPII vesicle coating [GO:0048208]; dendrite development [GO:0016358]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; vesicle coating [GO:0006901]; vesicle tethering [GO:0099022]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0005737; GO:0005783; GO:0005795; GO:0005886; GO:0006888; GO:0006901; GO:0006914; GO:0008021; GO:0016192; GO:0016358; GO:0030008; GO:0030425; GO:0045202; GO:0045211; GO:0048208; GO:0099022; GO:1990071; GO:1990072 48152 XM_044309065.1 56 0 0 170 138 NA NA NA NA NA NA 48153 XM_044307314.1 0 0 0 23 32 NA NA NA NA NA NA 48154 XM_044309951.1 61 13 56 214 115 A7MBJ4 3.22e-24 Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) Bos taurus (Bovine) cell migration [GO:0016477]; negative regulation of receptor binding [GO:1900121]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; synaptic membrane adhesion [GO:0099560] GO:0004725; GO:0006470; GO:0008201; GO:0016020; GO:0016477; GO:0035335; GO:0099560; GO:1900121 48155 XM_029324826.2 3055 821 1158 3130 3269 Q96PV6 6.2e-86 Leukocyte receptor cluster member 8 Homo sapiens (Human) NA GO:0005634; GO:0032991 48156 XM_044324180.1 139 89 0 0 26 Q80X08 1.54e-46 WASH complex subunit 2 Rattus norvegicus (Rat) endocytic recycling [GO:0032456]; negative regulation of barbed-end actin filament capping [GO:2000813]; protein localization to endosome [GO:0036010]; regulation of substrate adhesion-dependent cell spreading [GO:1900024]; retrograde transport, endosome to Golgi [GO:0042147] GO:0005546; GO:0005547; GO:0005768; GO:0005769; GO:0005829; GO:0005886; GO:0010314; GO:0031901; GO:0032266; GO:0032456; GO:0036010; GO:0042147; GO:0043325; GO:0070273; GO:0071203; GO:0080025; GO:1900024; GO:1901981; GO:1905394; GO:2000813 48157 XM_044319758.1 0 0 0 21 0 Q5BIM1 2.91e-53 Tripartite motif-containing protein 45 Bos taurus (Bovine) bone development [GO:0060348]; positive regulation of DNA-templated transcription [GO:0045893] GO:0000785; GO:0004842; GO:0005654; GO:0005829; GO:0008270; GO:0045171; GO:0045893; GO:0060348 48158 XR_006392214.1 0 0 0 3 25 NA NA NA NA NA NA 48159 XR_006391339.1 105 27 37 18 106 A5PJU6 4.36e-43 Hydroxylysine kinase (5-hydroxy-L-lysine kinase) (EC 2.7.1.81) (Aminoglycoside phosphotransferase domain-containing protein 1) Bos taurus (Bovine) phosphorylation [GO:0016310] GO:0005737; GO:0016310; GO:0019202; GO:0047992 48160 XM_029356322.2 1856 1426 947 1309 1694 Q4V7T8 4.55e-74 Ropporin-1-like protein Xenopus laevis (African clawed frog) NA GO:0031514 48161 XM_044318946.1 76 32 25 42 84 Q5ZKZ9 2.84e-71 Lipase maturation factor 2 Gallus gallus (Chicken) protein maturation [GO:0051604] GO:0005789; GO:0051604 48162 XM_044318946.1 76 32 25 42 84 Q5ZKZ9 4.43e-50 Lipase maturation factor 2 Gallus gallus (Chicken) protein maturation [GO:0051604] GO:0005789; GO:0051604 48163 XR_006395969.1 80 68 6 12 49 Q07494 4.75e-24 Ephrin type-B receptor 1 (EC 2.7.10.1) (EPH-like kinase 6) (EK6) (cEK6) (Tyrosine-protein kinase receptor EPH-2) Gallus gallus (Chicken) axon guidance [GO:0007411]; cell chemotaxis [GO:0060326]; cell-substrate adhesion [GO:0031589]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; ephrin receptor signaling pathway [GO:0048013]; establishment of cell polarity [GO:0030010]; positive regulation of kinase activity [GO:0033674]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0004714; GO:0005005; GO:0005524; GO:0005886; GO:0007169; GO:0007411; GO:0030010; GO:0030425; GO:0031589; GO:0031901; GO:0033674; GO:0043005; GO:0043235; GO:0046328; GO:0046777; GO:0048013; GO:0051965; GO:0060326; GO:0060996; GO:0060997; GO:0070372 48164 XM_029337570.2 3 0 0 12 0 NA NA NA NA NA NA 48165 XM_029335443.2 109 206 22 66 25 A8J4S9 1.7e-180 Trehalase (EC 3.2.1.28) (Alpha,alpha-trehalase) (Alpha,alpha-trehalose glucohydrolase) Apis mellifera (Honeybee) trehalose metabolic process [GO:0005991] GO:0004555; GO:0005991; GO:0016020 48166 XM_044307827.1 0 4 0 3 8 NA NA NA NA NA NA 48167 XM_029343122.2 581 479 241 435 488 Q9UBI4 1.24e-67 Stomatin-like protein 1 (SLP-1) (EPB72-like protein 1) (Protein unc-24 homolog) (Stomatin-related protein) (STORP) Homo sapiens (Human) lipid transport [GO:0006869] GO:0005886; GO:0006869; GO:0031902; GO:0045121 48168 XM_029338458.2 56 25 90 91 211 A2VDX7 1e-65 Exonuclease V (Exo V) (EC 3.1.-.-) (Defects in morphology protein 1 homolog) Bos taurus (Bovine) interstrand cross-link repair [GO:0036297] GO:0003677; GO:0005634; GO:0005654; GO:0005829; GO:0036297; GO:0045145; GO:0046872; GO:0051539 48169 XM_044307963.1 88 26 0 147 33 NA NA NA NA NA NA 48170 XM_029329947.2 734 910 657 1019 912 NA NA NA NA NA NA 48171 XM_029336768.2 619 2111 459 1262 460 Q29RU9 4.42e-89 Peroxisomal sarcosine oxidase (PSO) (EC 1.5.3.1) (EC 1.5.3.7) (L-pipecolate oxidase) (L-pipecolic acid oxidase) Bos taurus (Bovine) L-lysine catabolic process to acetyl-CoA via L-pipecolate [GO:0033514] GO:0005777; GO:0008115; GO:0033514; GO:0050031; GO:0050660 48172 XM_044321961.1 655 546 436 717 836 O60287 1.42e-85 Nucleolar pre-ribosomal-associated protein 1 (Nucleolar protein 254 kDa) (URB1 ribosome biogenesis 1 homolog) Homo sapiens (Human) maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000466]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463] GO:0000463; GO:0000466; GO:0001650; GO:0003723; GO:0005730 48173 XM_044321961.1 655 546 436 717 836 O60287 1.27e-50 Nucleolar pre-ribosomal-associated protein 1 (Nucleolar protein 254 kDa) (URB1 ribosome biogenesis 1 homolog) Homo sapiens (Human) maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000466]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463] GO:0000463; GO:0000466; GO:0001650; GO:0003723; GO:0005730 48174 XM_029332736.2 673 597 478 535 505 O15182 4.31e-91 Centrin-3 Homo sapiens (Human) cell division [GO:0051301]; centrosome cycle [GO:0007098]; mRNA transport [GO:0051028]; protein transport [GO:0015031] GO:0005509; GO:0005730; GO:0005737; GO:0005813; GO:0005814; GO:0005815; GO:0007098; GO:0008017; GO:0015031; GO:0031683; GO:0032391; GO:0036064; GO:0044615; GO:0051028; GO:0051301; GO:0070390 48175 XR_006394562.1 103 389 320 490 121 NA NA NA NA NA NA 48176 XM_029343336.2 1339 1590 1315 713 1242 Q9NV56 5.63e-31 MRG/MORF4L-binding protein (MRG-binding protein) (Up-regulated in colon cancer 4) (Urcc4) Homo sapiens (Human) chromatin organization [GO:0006325]; histone acetylation [GO:0016573]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of double-strand break repair [GO:2000779]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000786; GO:0005654; GO:0006325; GO:0006357; GO:0016573; GO:0035267; GO:0042981; GO:0043967; GO:0043968; GO:0045893; GO:0051726; GO:1905168; GO:2000779 48177 XM_029335600.2 452 49 0 50 40 O70521 4.54e-37 Regulator of G-protein signaling 19 (RGS19) (G-alpha-interacting protein) (GAIP) Rattus norvegicus (Rat) negative regulation of signal transduction [GO:0009968]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; response to ethanol [GO:0045471] GO:0000139; GO:0001965; GO:0005096; GO:0005737; GO:0005903; GO:0008277; GO:0009968; GO:0016020; GO:0030136; GO:0045121; GO:0045471 48178 XM_044311660.1 427 55 210 218 316 Q9H2P9 2.57e-136 Diphthine methyl ester synthase (EC 2.1.1.314) (Diphthamide biosynthesis methyltransferase) Homo sapiens (Human) methylation [GO:0032259]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183] GO:0004164; GO:0005829; GO:0017183; GO:0032259 48179 XM_029333053.2 474 218 223 600 192 Q2T9T9 2.81e-54 F-box/WD repeat-containing protein 9 (F-box and WD-40 domain-containing protein 9) Bos taurus (Bovine) NA NA 48180 XM_029323633.2 612 238 568 383 957 NA NA NA NA NA NA 48181 XM_029344048.2 1430 1267 547 958 615 NA NA NA NA NA NA 48182 XM_044309366.1 34 52 0 47 32 NA NA NA NA NA NA 48183 XM_044307679.1 736 437 107 141 207 Q8IVE3 0 Pleckstrin homology domain-containing family H member 2 Homo sapiens (Human) negative regulation of actin filament depolymerization [GO:0030835] GO:0003779; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0016604; GO:0030027; GO:0030835; GO:0030864 48184 XM_029332843.2 14635 10831 9897 11099 9337 Q8NHP8 1.33e-168 Putative phospholipase B-like 2 (EC 3.1.1.-) (76 kDa protein) (p76) (LAMA-like protein 2) (Lamina ancestor homolog 2) (Phospholipase B domain-containing protein 2) [Cleaved into: Putative phospholipase B-like 2 32 kDa form; Putative phospholipase B-like 2 45 kDa form] Homo sapiens (Human) phospholipid catabolic process [GO:0009395] GO:0004620; GO:0005576; GO:0009395; GO:0043202; GO:0070062 48185 XM_044306961.1 132 62 43 143 139 B3EX02 1.34e-121 MAM and fibronectin type III domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 48186 XM_044306961.1 132 62 43 143 139 B3EX02 1.05e-117 MAM and fibronectin type III domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 48187 XM_044306961.1 132 62 43 143 139 B3EX02 6.44e-45 MAM and fibronectin type III domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 48188 XM_044306961.1 132 62 43 143 139 B3EX02 5.82e-30 MAM and fibronectin type III domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 48189 XM_044306961.1 132 62 43 143 139 B3EX02 6.61e-26 MAM and fibronectin type III domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 48190 XM_029326902.2 1045 1114 1295 1056 1066 Q6NYV5 6.8e-70 Histone deacetylase complex subunit SAP30L (Sin3 corepressor complex subunit SAP30L) (Sin3-associated protein p30-like) Danio rerio (Zebrafish) (Brachydanio rerio) heart looping [GO:0001947]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355] GO:0000118; GO:0000122; GO:0001947; GO:0003677; GO:0003712; GO:0005730; GO:0006355; GO:0008270; GO:0010314; GO:0031491; GO:0032266; GO:0042393; GO:0044378; GO:0070273 48191 XM_029343682.2 678 663 340 555 432 Q6NRH3 1.12e-49 Coiled-coil domain-containing protein 149 Xenopus laevis (African clawed frog) NA NA 48192 XM_044322958.1 16296 16421 10917 15159 11784 P61210 1.12e-118 ADP-ribosylation factor 1 (EC 3.6.5.2) (lARF1) Locusta migratoria (Migratory locust) establishment of localization in cell [GO:0051649]; protein transport [GO:0015031]; system development [GO:0048731]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0003924; GO:0005525; GO:0015031; GO:0016192; GO:0048731; GO:0051649 48193 XM_044312266.1 0 314 0 0 18 NA NA NA NA NA NA 48194 XR_003825370.2 0 2 18 38 57 NA NA NA NA NA NA 48195 XM_044323426.1 306 180 0 0 280 Q1G7G9 5.38e-24 TALPID3 protein Gallus gallus (Chicken) centrosome localization [GO:0051642]; cilium assembly [GO:0060271]; motile cilium assembly [GO:0044458]; smoothened signaling pathway [GO:0007224] GO:0005737; GO:0005813; GO:0005814; GO:0007224; GO:0036064; GO:0044458; GO:0051642; GO:0060271 48196 XM_029337398.2 541 256 171 251 472 Q06441 1.16e-174 Thrombospondin-4 Xenopus laevis (African clawed frog) cell adhesion [GO:0007155]; positive regulation of cell division [GO:0051781]; response to unfolded protein [GO:0006986] GO:0005509; GO:0005615; GO:0005783; GO:0006986; GO:0007155; GO:0008083; GO:0016529; GO:0051781; GO:0062023 48197 XM_044329157.1 26 164 84 47 79 Q9NVU0 5.04e-77 DNA-directed RNA polymerase III subunit RPC5 (RNA polymerase III subunit C5) (DNA-directed RNA polymerase III 80 kDa polypeptide) Homo sapiens (Human) defense response to virus [GO:0051607]; DNA-templated transcription [GO:0006351]; innate immune response [GO:0045087] GO:0005654; GO:0005666; GO:0005829; GO:0006351; GO:0045087; GO:0051607 48198 XM_029343076.2 67 18 19 55 53 NA NA NA NA NA NA 48199 XM_044309590.1 17 10 3 10 34 NA NA NA NA NA NA 48200 XM_044327505.1 165 0 54 3 192 NA NA NA NA NA NA 48201 XM_044307396.1 180 171 124 343 65 Q8BZM0 6.01e-40 Kelch-like protein 12 (CUL3-interacting protein 1) Mus musculus (Mouse) COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; protein monoubiquitination [GO:0006513]; Wnt signaling pathway [GO:0016055] GO:0006513; GO:0006888; GO:0014029; GO:0014032; GO:0016055; GO:0030127; GO:0030134; GO:0031463; GO:0034451; GO:0042802; GO:0043231; GO:0048208 48202 XR_006391778.1 7 8 1 3 12 NA NA NA NA NA NA 48203 XM_044328943.1 4044 2489 2504 5693 4418 NA NA NA NA NA NA 48204 XM_044315982.1 1024 5251 1501 5174 7523 R1CW23 1.61e-102 Dimethylsulfonioproprionate lyase 7 (DMSP lyase 7) (EC 4.4.1.3) (Dimethylpropiothetin dethiomethylase 7) Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi) NA GO:0047869 48205 XM_044324330.1 0 0 73 176 395 NA NA NA NA NA NA 48206 XM_044309155.1 105 166 184 628 0 P39059 3.38e-29 Collagen alpha-1(XV) chain [Cleaved into: Restin (Endostatin-XV) (Related to endostatin) (Restin-I); Restin-2 (Restin-II); Restin-3 (Restin-III); Restin-4 (Restin-IV)] Homo sapiens (Human) angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; endothelial cell morphogenesis [GO:0001886]; extracellular matrix organization [GO:0030198]; signal transduction [GO:0007165] GO:0001525; GO:0001886; GO:0005201; GO:0005576; GO:0005582; GO:0005615; GO:0005788; GO:0007155; GO:0007165; GO:0016020; GO:0030020; GO:0030198; GO:0031012; GO:0062023; GO:0070062 48207 XM_044325918.1 478 242 235 332 438 A2RUV0 1.58e-147 Neurogenic locus notch homolog protein 1 (Notch 1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; cilium assembly [GO:0060271]; Notch signaling involved in heart development [GO:0061314]; regulation of developmental process [GO:0050793]; regulation of DNA-templated transcription [GO:0006355] GO:0001525; GO:0005509; GO:0005634; GO:0005886; GO:0006355; GO:0030154; GO:0038023; GO:0050793; GO:0060271; GO:0061314 48208 XM_044325918.1 478 242 235 332 438 A2RUV0 1.23e-140 Neurogenic locus notch homolog protein 1 (Notch 1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; cilium assembly [GO:0060271]; Notch signaling involved in heart development [GO:0061314]; regulation of developmental process [GO:0050793]; regulation of DNA-templated transcription [GO:0006355] GO:0001525; GO:0005509; GO:0005634; GO:0005886; GO:0006355; GO:0030154; GO:0038023; GO:0050793; GO:0060271; GO:0061314 48209 XM_044325918.1 478 242 235 332 438 A2RUV0 2.9e-138 Neurogenic locus notch homolog protein 1 (Notch 1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; cilium assembly [GO:0060271]; Notch signaling involved in heart development [GO:0061314]; regulation of developmental process [GO:0050793]; regulation of DNA-templated transcription [GO:0006355] GO:0001525; GO:0005509; GO:0005634; GO:0005886; GO:0006355; GO:0030154; GO:0038023; GO:0050793; GO:0060271; GO:0061314 48210 XM_044325918.1 478 242 235 332 438 A2RUV0 5.2e-137 Neurogenic locus notch homolog protein 1 (Notch 1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; cilium assembly [GO:0060271]; Notch signaling involved in heart development [GO:0061314]; regulation of developmental process [GO:0050793]; regulation of DNA-templated transcription [GO:0006355] GO:0001525; GO:0005509; GO:0005634; GO:0005886; GO:0006355; GO:0030154; GO:0038023; GO:0050793; GO:0060271; GO:0061314 48211 XM_044325918.1 478 242 235 332 438 A2RUV0 1.19e-134 Neurogenic locus notch homolog protein 1 (Notch 1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; cilium assembly [GO:0060271]; Notch signaling involved in heart development [GO:0061314]; regulation of developmental process [GO:0050793]; regulation of DNA-templated transcription [GO:0006355] GO:0001525; GO:0005509; GO:0005634; GO:0005886; GO:0006355; GO:0030154; GO:0038023; GO:0050793; GO:0060271; GO:0061314 48212 XM_044325918.1 478 242 235 332 438 A2RUV0 1.45e-111 Neurogenic locus notch homolog protein 1 (Notch 1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; cilium assembly [GO:0060271]; Notch signaling involved in heart development [GO:0061314]; regulation of developmental process [GO:0050793]; regulation of DNA-templated transcription [GO:0006355] GO:0001525; GO:0005509; GO:0005634; GO:0005886; GO:0006355; GO:0030154; GO:0038023; GO:0050793; GO:0060271; GO:0061314 48213 XM_044325918.1 478 242 235 332 438 A2RUV0 2.4e-90 Neurogenic locus notch homolog protein 1 (Notch 1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; cilium assembly [GO:0060271]; Notch signaling involved in heart development [GO:0061314]; regulation of developmental process [GO:0050793]; regulation of DNA-templated transcription [GO:0006355] GO:0001525; GO:0005509; GO:0005634; GO:0005886; GO:0006355; GO:0030154; GO:0038023; GO:0050793; GO:0060271; GO:0061314 48214 XM_044325918.1 478 242 235 332 438 A2RUV0 1.03e-85 Neurogenic locus notch homolog protein 1 (Notch 1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; cilium assembly [GO:0060271]; Notch signaling involved in heart development [GO:0061314]; regulation of developmental process [GO:0050793]; regulation of DNA-templated transcription [GO:0006355] GO:0001525; GO:0005509; GO:0005634; GO:0005886; GO:0006355; GO:0030154; GO:0038023; GO:0050793; GO:0060271; GO:0061314 48215 XM_044315848.1 38 16 48 31 126 NA NA NA NA NA NA 48216 XM_044317526.1 94 53 79 243 58 Q96AY4 1.1e-95 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 48217 XM_044317526.1 94 53 79 243 58 Q96AY4 1.33e-91 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 48218 XM_044317526.1 94 53 79 243 58 Q96AY4 2.23e-89 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 48219 XM_044317526.1 94 53 79 243 58 Q96AY4 4.12e-89 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 48220 XM_044317526.1 94 53 79 243 58 Q96AY4 1.99e-88 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 48221 XM_044317526.1 94 53 79 243 58 Q96AY4 8.97e-86 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 48222 XM_044317526.1 94 53 79 243 58 Q96AY4 2.34e-77 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 48223 XM_044317526.1 94 53 79 243 58 Q96AY4 4.91e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 48224 XR_003827204.2 12 30 79 43 24 NA NA NA NA NA NA 48225 XM_029343375.2 169 109 73 143 200 P29083 4.62e-47 General transcription factor IIE subunit 1 (General transcription factor IIE 56 kDa subunit) (Transcription initiation factor IIE subunit alpha) (TFIIE-alpha) Homo sapiens (Human) transcription by RNA polymerase II [GO:0006366]; transcription initiation at RNA polymerase II promoter [GO:0006367]; transcription open complex formation at RNA polymerase II promoter [GO:0001113] GO:0001113; GO:0005634; GO:0005654; GO:0005669; GO:0005673; GO:0005829; GO:0006366; GO:0006367; GO:0016251; GO:0046872; GO:0060090; GO:0097550 48226 XM_044310845.1 9 0 0 0 0 Q99570 2.22e-29 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 48227 XM_044310845.1 9 0 0 0 0 Q99570 2.22e-29 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 48228 XM_029335282.2 38 20 0 0 0 Q09694 7.08e-91 Saccharopine dehydrogenase [NAD(+), L-lysine-forming] (SDH) (EC 1.5.1.7) (Lysine--2-oxoglutarate reductase) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) lysine biosynthetic process [GO:0009085]; lysine biosynthetic process via aminoadipic acid [GO:0019878] GO:0004753; GO:0004754; GO:0005737; GO:0009085; GO:0019878 48229 XM_044315164.1 0 0 0 9 0 P20664 1.91e-158 DNA primase small subunit (EC 2.7.7.102) (DNA primase 49 kDa subunit) (p49) Mus musculus (Mouse) DNA replication initiation [GO:0006270]; DNA replication, synthesis of RNA primer [GO:0006269] GO:0000287; GO:0003896; GO:0005658; GO:0006269; GO:0006270; GO:0008270; GO:0032553 48230 XM_029337411.2 454 566 161 647 635 Q9Y2Y9 3.54e-39 Krueppel-like factor 13 (Basic transcription element-binding protein 3) (BTE-binding protein 3) (Novel Sp1-like zinc finger transcription factor 1) (RANTES factor of late activated T-lymphocytes 1) (RFLAT-1) (Transcription factor BTEB3) (Transcription factor NSLP1) Homo sapiens (Human) negative regulation of cell population proliferation [GO:0008285]; negative regulation of erythrocyte differentiation [GO:0045647]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366] GO:0000785; GO:0000978; GO:0000981; GO:0001228; GO:0005634; GO:0006357; GO:0006366; GO:0008285; GO:0045647; GO:0046872; GO:1990837 48231 XM_044320385.1 2 0 8 19 11 Q09575 3.43e-54 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 48232 XM_044327179.1 0 0 0 0 25 Q05209 5.83e-75 Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (PTP-PEST) (Protein-tyrosine phosphatase G1) (PTPG1) Homo sapiens (Human) cellular response to epidermal growth factor stimulus [GO:0071364]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; tissue regeneration [GO:0042246] GO:0002102; GO:0004721; GO:0004725; GO:0004726; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005925; GO:0006470; GO:0017124; GO:0035335; GO:0042058; GO:0042246; GO:0042995; GO:0071364; GO:1901185; GO:2000587 48233 XM_029338898.2 21 3 30 1 133 Q7RTX7 1.28e-45 Cation channel sperm-associated protein 4 (CatSper4) Homo sapiens (Human) establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; regulation of ion transmembrane transport [GO:0034765]; sodium ion transport [GO:0006814]; sperm capacitation [GO:0048240] GO:0001669; GO:0005227; GO:0005245; GO:0005886; GO:0006814; GO:0030317; GO:0034765; GO:0036128; GO:0048240; GO:0051649; GO:0097228 48234 XM_029345625.2 68 35 19 17 20 NA NA NA NA NA NA 48235 XM_029345014.2 11733 9451 9994 12343 7723 Q3SYV5 1.35e-50 Tetraspanin-33 (Tspan-33) Bos taurus (Bovine) NA GO:0005737; GO:0005886; GO:0005912 48236 XM_029325514.2 0 1 43 0 0 NA NA NA NA NA NA 48237 XM_044313820.1 6 0 15 22 0 NA NA NA NA NA NA 48238 XM_029331852.2 344 290 172 346 308 Q6ZT07 0 TBC1 domain family member 9 (TBC1 domain family member 9A) Homo sapiens (Human) activation of GTPase activity [GO:0090630] GO:0005096; GO:0005509; GO:0090630 48239 XM_029338804.2 313 251 231 248 537 B3EWZ7 4.7e-68 Threonine-rich protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 48240 XR_006397455.1 53 35 84 157 100 NA NA NA NA NA NA 48241 XM_044309442.1 293 225 283 270 372 NA NA NA NA NA NA 48242 XM_029349143.2 401 336 181 251 213 Q32KI9 0 Arylsulfatase I (ASI) (EC 3.1.6.-) Mus musculus (Mouse) NA GO:0005576; GO:0005783; GO:0008484; GO:0046872 48243 XM_029335839.2 777 0 0 182 1 NA NA NA NA NA NA 48244 XM_029338518.2 2732 2969 860 1564 1105 P27465 1.64e-111 Phosphatidylserine decarboxylase proenzyme, mitochondrial (EC 4.1.1.65) [Cleaved into: Phosphatidylserine decarboxylase beta chain; Phosphatidylserine decarboxylase alpha chain] Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) lipid droplet formation [GO:0140042]; mitochondrial protein catabolic process [GO:0035694]; phosphatidylethanolamine biosynthetic process [GO:0006646]; protein autoprocessing [GO:0016540]; regulation of mitochondrion organization [GO:0010821] GO:0004609; GO:0005634; GO:0005739; GO:0005743; GO:0005811; GO:0006646; GO:0010821; GO:0016540; GO:0035694; GO:0140042 48245 XM_044317410.1 42 45 3 27 81 NA NA NA NA NA NA 48246 XM_029330166.2 357 169 254 386 431 Q864U6 9.95e-26 UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1 (Beta-1,3-GalNAc-T1) (EC 2.4.1.79) (Beta-1,3-galactosyltransferase 3) (Beta-1,3-GalTase 3) (Beta3Gal-T3) (Beta3GalT3) (b3Gal-T3) (Beta-3-Gx-T3) (Galactosylgalactosylglucosylceramide beta-D-acetyl-galactosaminyltransferase) (Globoside synthase) (UDP-N-acetylgalactosamine:globotriaosylceramide beta-1,3-N-acetylgalactosaminyltransferase) Sus scrofa (Pig) lipid metabolic process [GO:0006629]; oligosaccharide biosynthetic process [GO:0009312]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0006629; GO:0008194; GO:0008499; GO:0009312; GO:0016757; GO:0047273 48247 XM_044317311.1 35 21 26 38 41 NA NA NA NA NA NA 48248 XM_044314615.1 70 52 0 110 133 NA NA NA NA NA NA 48249 XM_044323123.1 271 129 252 175 236 P16157 1.52e-69 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 48250 XM_044323123.1 271 129 252 175 236 P16157 1.54e-55 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 48251 XM_044323123.1 271 129 252 175 236 P16157 3.92e-55 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 48252 XM_044323123.1 271 129 252 175 236 P16157 6.35e-41 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 48253 XM_044323123.1 271 129 252 175 236 P16157 4.64e-33 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 48254 XM_044325333.1 2 8 80 21 23 Q9M2U3 5.19e-26 Protein ALP1-like (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) NA GO:0000118; GO:0004518; GO:0046872 48255 XR_006391660.1 228 72 250 259 532 NA NA NA NA NA NA 48256 XM_044320139.1 6 12 6 3 15 NA NA NA NA NA NA 48257 XM_044309969.1 1 553 4 9 5 NA NA NA NA NA NA 48258 XM_029332849.2 1829 1675 816 2993 12 P26686 5.09e-72 Serine-arginine protein 55 (SRP55) (52 kDa bracketing protein) (B52 protein) (Protein enhancer of deformed) Drosophila melanogaster (Fruit fly) defense response to virus [GO:0051607]; mitotic cell cycle [GO:0000278]; mitotic G1/S transition checkpoint signaling [GO:0044819]; mRNA splicing, via spliceosome [GO:0000398]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of gene expression [GO:0010468]; regulation of mRNA 3'-end processing [GO:0031440]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of transcriptional start site selection at RNA polymerase II promoter [GO:0001178]; RNA splicing [GO:0008380] GO:0000278; GO:0000381; GO:0000398; GO:0000791; GO:0001178; GO:0003723; GO:0003729; GO:0005634; GO:0005700; GO:0008380; GO:0010468; GO:0016607; GO:0031440; GO:0044819; GO:0048024; GO:0051607; GO:0071011; GO:0071013 48259 XM_029335494.2 1360 842 693 1083 852 NA NA NA NA NA NA 48260 XM_044315361.1 73 28 28 96 271 NA NA NA NA NA NA 48261 XM_029343363.2 9429 6627 3186 8865 4841 Q9V9J3 0 Tyrosine-protein kinase Src42A (EC 2.7.10.2) (Tyrosine-protein kinase Src41) (Dsrc41) Drosophila melanogaster (Fruit fly) actin filament bundle assembly [GO:0051017]; adherens junction organization [GO:0034332]; apoptotic cell clearance [GO:0043277]; axon guidance [GO:0007411]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; compound eye development [GO:0048749]; defense response to bacterium [GO:0042742]; dorsal closure [GO:0007391]; dorsal closure, spreading of leading edge cells [GO:0007395]; epithelial cell-cell adhesion [GO:0090136]; hydrogen peroxide mediated signaling pathway [GO:0071588]; imaginal disc fusion, thorax closure [GO:0046529]; imaginal disc-derived wing morphogenesis [GO:0007476]; innate immune response [GO:0045087]; intestinal stem cell homeostasis [GO:0036335]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of synaptic assembly at neuromuscular junction [GO:0045886]; open tracheal system development [GO:0007424]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of inflammatory response to wounding [GO:0106016]; positive regulation of sevenless signaling pathway [GO:0045874]; protein phosphorylation [GO:0006468]; regulation of synaptic plasticity [GO:0048167]; salivary gland morphogenesis [GO:0007435]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0004713; GO:0004715; GO:0005102; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006468; GO:0007169; GO:0007391; GO:0007395; GO:0007411; GO:0007424; GO:0007435; GO:0007476; GO:0016477; GO:0018108; GO:0030154; GO:0031234; GO:0034332; GO:0036335; GO:0042059; GO:0042742; GO:0043277; GO:0045087; GO:0045742; GO:0045874; GO:0045886; GO:0046529; GO:0048167; GO:0048749; GO:0051017; GO:0070374; GO:0071588; GO:0090136; GO:0106016 48262 XM_029346751.2 18 198 95 74 133 NA NA NA NA NA NA 48263 XM_044314470.1 0 0 0 0 9 NA NA NA NA NA NA 48264 XM_044324559.1 3 51 69 1 45 NA NA NA NA NA NA 48265 XM_029329494.2 6668 7295 3927 5835 5715 P68037 2.67e-71 Ubiquitin-conjugating enzyme E2 L3 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme L3) (UbcM4) (Ubiquitin carrier protein L3) (Ubiquitin-protein ligase L3) Mus musculus (Mouse) brain development [GO:0007420]; cell cycle phase transition [GO:0044770]; cell population proliferation [GO:0008283]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to steroid hormone stimulus [GO:0071383]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein K11-linked ubiquitination [GO:0070979]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of DNA-templated transcription [GO:0006355]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000151; GO:0000209; GO:0003713; GO:0004842; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006355; GO:0006511; GO:0007420; GO:0008283; GO:0016567; GO:0031398; GO:0031625; GO:0044770; GO:0051443; GO:0061631; GO:0070979; GO:0071383; GO:0071385; GO:0097027; GO:0098793 48266 XM_029340031.2 0 27 0 0 0 O93403 3.94e-26 Carbohydrate sulfotransferase 3 (EC 2.8.2.17) (EC 2.8.2.21) (Chondroitin 6-O-sulfotransferase 1) (C6ST-1) (Nervous system involved sulfotransferase) Tetronarce californica (Pacific electric ray) (Torpedo californica) carbohydrate metabolic process [GO:0005975]; chondroitin sulfate biosynthetic process [GO:0030206] GO:0000139; GO:0005975; GO:0008459; GO:0030206 48267 XM_044317497.1 23 26 27 54 67 NA NA NA NA NA NA 48268 XM_044321978.1 151 110 102 290 99 Q7TS68 1.04e-132 tRNA (cytosine(72)-C(5))-methyltransferase NSUN6 (EC 2.1.1.-) (NOL1/NOP2/Sun domain family member 6) Mus musculus (Mouse) RNA methylation [GO:0001510]; tRNA C5-cytosine methylation [GO:0002946]; tRNA methylation [GO:0030488] GO:0000049; GO:0001510; GO:0002946; GO:0005654; GO:0005737; GO:0016428; GO:0030488 48269 XM_044315151.1 0 0 0 0 6 NA NA NA NA NA NA 48270 XM_044320427.1 96 21 2 7 24 NA NA NA NA NA NA 48271 XM_044310859.1 44 31 8 0 0 Q99570 1.13e-36 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 48272 XM_044322444.1 7 12 94 73 117 NA NA NA NA NA NA 48273 XM_044315839.1 24 62 135 49 2342 NA NA NA NA NA NA 48274 XM_044319004.1 13 1 9 24 10 Q99315 4.53e-63 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 48275 XM_044319004.1 13 1 9 24 10 Q99315 4.53e-63 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 48276 XM_029336894.2 87 4 90 0 0 NA NA NA NA NA NA 48277 XM_044326803.1 4 62 36 90 112 NA NA NA NA NA NA 48278 XM_044325346.1 38 13 31 30 78 P48733 8.83e-28 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Bos taurus (Bovine) antibacterial innate immune response [GO:0140367]; defense response to Gram-negative bacterium [GO:0050829] GO:0000922; GO:0005201; GO:0005509; GO:0005576; GO:0005929; GO:0016020; GO:0016323; GO:0016324; GO:0031012; GO:0050829; GO:0060170; GO:0140367 48279 XM_044312020.1 29 0 0 0 117 Q58A42 1.47e-67 Protein DD3-3 Dictyostelium discoideum (Social amoeba) NA GO:0016020 48280 XM_029328745.2 30 10 59 46 81 G3MZR2 5.1e-44 Alpha-(1,3)-fucosyltransferase 7 (bfut7) (EC 2.4.1.-) (Fucosyltransferase 7) (Fucosyltransferase VII) (Fuc-TVII) (FucT-VII) (Galactoside 3-L-fucosyltransferase) (Selectin ligand synthase) Bos taurus (Bovine) CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation [GO:0002361]; ceramide metabolic process [GO:0006672]; embryo implantation [GO:0007566]; fucosylation [GO:0036065]; inflammatory response [GO:0006954]; leukocyte migration involved in immune response [GO:0002522]; leukocyte migration involved in inflammatory response [GO:0002523]; lymphocyte migration into lymph node [GO:0097022]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of leukocyte tethering or rolling [GO:1903238]; positive regulation of neutrophil migration [GO:1902624]; protein glycosylation [GO:0006486]; regulation of cell adhesion molecule production [GO:0060353]; regulation of cell-cell adhesion [GO:0022407]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of neutrophil extravasation [GO:2000389]; regulation of type IV hypersensitivity [GO:0001807]; T cell migration [GO:0072678] GO:0001807; GO:0002361; GO:0002522; GO:0002523; GO:0005802; GO:0006486; GO:0006672; GO:0006954; GO:0007566; GO:0016020; GO:0017083; GO:0022407; GO:0022409; GO:0036065; GO:0045785; GO:0046626; GO:0046920; GO:0060353; GO:0072678; GO:0097022; GO:1902624; GO:1903238; GO:1904996; GO:2000389 48281 XM_029351846.2 2124 2759 1709 1433 2151 P84079 1.79e-117 ADP-ribosylation factor 1 (EC 3.6.5.2) Rattus norvegicus (Rat) actin filament organization [GO:0007015]; cellular copper ion homeostasis [GO:0006878]; cellular response to virus [GO:0098586]; dendritic spine organization [GO:0097061]; Golgi to transport vesicle transport [GO:0055108]; intracellular protein transport [GO:0006886]; long-term synaptic depression [GO:0060292]; lysosomal membrane organization [GO:0097212]; mitotic cleavage furrow ingression [GO:1990386]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of endocytosis [GO:0045807]; positive regulation of ER to Golgi vesicle-mediated transport [GO:1902953]; positive regulation of late endosome to lysosome transport [GO:1902824]; positive regulation of protein secretion [GO:0050714]; positive regulation of sodium ion transmembrane transport [GO:1902307]; postsynaptic actin cytoskeleton organization [GO:0098974]; regulation of Arp2/3 complex-mediated actin nucleation [GO:0034315]; regulation of phospholipid metabolic process [GO:1903725]; regulation of receptor internalization [GO:0002090]; synaptic vesicle budding [GO:0070142]; very-low-density lipoprotein particle assembly [GO:0034379]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0000287; GO:0002090; GO:0003924; GO:0005525; GO:0005737; GO:0005770; GO:0005794; GO:0005829; GO:0005886; GO:0006878; GO:0006886; GO:0007015; GO:0012505; GO:0014069; GO:0016192; GO:0019003; GO:0019904; GO:0030017; GO:0031252; GO:0032991; GO:0034315; GO:0034379; GO:0043005; GO:0045807; GO:0045956; GO:0050714; GO:0055108; GO:0060292; GO:0060999; GO:0070142; GO:0097061; GO:0097212; GO:0098586; GO:0098974; GO:0098978; GO:1902307; GO:1902824; GO:1902953; GO:1903725; GO:1990386; GO:1990583 48282 XR_003827413.2 504 295 162 207 90 Q9HC58 6.4e-69 Sodium/potassium/calcium exchanger 3 (Na(+)/K(+)/Ca(2+)-exchange protein 3) (Solute carrier family 24 member 3) Homo sapiens (Human) bone mineralization [GO:0030282]; calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; ion transport [GO:0006811]; negative regulation of gene expression [GO:0010629]; positive regulation of gene expression [GO:0010628]; potassium ion transmembrane transport [GO:0071805]; sodium ion transmembrane transport [GO:0035725]; transport across blood-brain barrier [GO:0150104] GO:0005262; GO:0005886; GO:0006811; GO:0006874; GO:0008273; GO:0010628; GO:0010629; GO:0015293; GO:0030282; GO:0035725; GO:0070588; GO:0071805; GO:0071944; GO:0150104 48283 XR_003827413.2 504 295 162 207 90 Q9HC58 1.33e-45 Sodium/potassium/calcium exchanger 3 (Na(+)/K(+)/Ca(2+)-exchange protein 3) (Solute carrier family 24 member 3) Homo sapiens (Human) bone mineralization [GO:0030282]; calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; ion transport [GO:0006811]; negative regulation of gene expression [GO:0010629]; positive regulation of gene expression [GO:0010628]; potassium ion transmembrane transport [GO:0071805]; sodium ion transmembrane transport [GO:0035725]; transport across blood-brain barrier [GO:0150104] GO:0005262; GO:0005886; GO:0006811; GO:0006874; GO:0008273; GO:0010628; GO:0010629; GO:0015293; GO:0030282; GO:0035725; GO:0070588; GO:0071805; GO:0071944; GO:0150104 48284 XM_029333313.2 18 0 0 8 8 NA NA NA NA NA NA 48285 XM_044326168.1 4 4 4 9 21 NA NA NA NA NA NA 48286 XM_044314678.1 71 4 203 24 458 NA NA NA NA NA NA 48287 XM_029339666.2 21 0 27 26 60 NA NA NA NA NA NA 48288 XR_003826687.2 112 157 113 187 114 NA NA NA NA NA NA 48289 XM_044308380.1 0 10 26 0 24 A7MB54 3.36e-25 H2.0-like homeobox protein (Homeobox protein HLX1) Bos taurus (Bovine) embryonic digestive tract morphogenesis [GO:0048557]; enteric nervous system development [GO:0048484]; epithelial cell proliferation [GO:0050673]; liver development [GO:0001889]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; organ growth [GO:0035265]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of organ growth [GO:0046622]; positive regulation of T-helper 1 cell differentiation [GO:0045627]; skeletal muscle tissue development [GO:0007519]; T-helper 1 cell differentiation [GO:0045063]; T-helper 2 cell differentiation [GO:0045064] GO:0000981; GO:0001889; GO:0005634; GO:0007519; GO:0035265; GO:0043565; GO:0045063; GO:0045064; GO:0045627; GO:0045629; GO:0046622; GO:0048484; GO:0048557; GO:0050673; GO:0050679 48290 XM_044325050.1 16 1 8 4 137 NA NA NA NA NA NA 48291 XM_029348006.2 247 148 160 218 221 Q8C729 7.56e-43 Hyccin 2 Mus musculus (Mouse) phosphatidylinositol phosphate biosynthetic process [GO:0046854]; protein localization to plasma membrane [GO:0072659] GO:0005829; GO:0005886; GO:0046854; GO:0072659 48292 XM_044312767.1 44 24 27 38 106 NA NA NA NA NA NA 48293 XM_029355339.2 515 537 266 521 568 Q9UBZ9 9.38e-139 DNA repair protein REV1 (EC 2.7.7.-) (Alpha integrin-binding protein 80) (AIBP80) (Rev1-like terminal deoxycytidyl transferase) Homo sapiens (Human) DNA replication [GO:0006260]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; response to UV [GO:0009411] GO:0003684; GO:0003887; GO:0005654; GO:0006260; GO:0009411; GO:0017125; GO:0042276; GO:0046872; GO:0070987 48294 XM_029355339.2 515 537 266 521 568 Q9UBZ9 5.11e-24 DNA repair protein REV1 (EC 2.7.7.-) (Alpha integrin-binding protein 80) (AIBP80) (Rev1-like terminal deoxycytidyl transferase) Homo sapiens (Human) DNA replication [GO:0006260]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; response to UV [GO:0009411] GO:0003684; GO:0003887; GO:0005654; GO:0006260; GO:0009411; GO:0017125; GO:0042276; GO:0046872; GO:0070987 48295 XM_029323592.2 0 5 0 111 54 P24507 1.45e-36 Synaptotagmin-C (Synaptic vesicle protein O-p65-C) Diplobatis ommata (Ocellated electric ray) (Discopyge ommata) NA GO:0030672; GO:0046872 48296 XM_044317970.1 42 26 4 47 2 NA NA NA NA NA NA 48297 XM_044310995.1 7 9 0 2 27 NA NA NA NA NA NA 48298 XM_029328672.2 77 0 63 60 47 NA NA NA NA NA NA 48299 XM_029333269.2 12 14 12 16 121 P69526 1.04e-83 Transmembrane protease serine 9 (EC 3.4.21.-) (Polyserase-I) (Polyserine protease 1) (Polyserase-1) [Cleaved into: Serase-1; Serase-2; Serase-3] Rattus norvegicus (Rat) plasminogen activation [GO:0031639]; proteolysis [GO:0006508] GO:0004252; GO:0005886; GO:0006508; GO:0008236; GO:0031639 48300 XM_029333269.2 12 14 12 16 121 P69526 3.58e-40 Transmembrane protease serine 9 (EC 3.4.21.-) (Polyserase-I) (Polyserine protease 1) (Polyserase-1) [Cleaved into: Serase-1; Serase-2; Serase-3] Rattus norvegicus (Rat) plasminogen activation [GO:0031639]; proteolysis [GO:0006508] GO:0004252; GO:0005886; GO:0006508; GO:0008236; GO:0031639 48301 XM_029333269.2 12 14 12 16 121 P69526 6.48e-35 Transmembrane protease serine 9 (EC 3.4.21.-) (Polyserase-I) (Polyserine protease 1) (Polyserase-1) [Cleaved into: Serase-1; Serase-2; Serase-3] Rattus norvegicus (Rat) plasminogen activation [GO:0031639]; proteolysis [GO:0006508] GO:0004252; GO:0005886; GO:0006508; GO:0008236; GO:0031639 48302 XM_029328736.2 5154 6487 5207 4393 3587 Q55FU9 5.19e-44 Ras-related protein Rab-24 Dictyostelium discoideum (Social amoeba) autophagy [GO:0006914]; intracellular protein transport [GO:0006886] GO:0003924; GO:0005525; GO:0005768; GO:0005776; GO:0005783; GO:0005793; GO:0005794; GO:0006886; GO:0006914; GO:0012505; GO:0016020; GO:0030139 48303 XM_044327547.1 52 26 116 37 133 NA NA NA NA NA NA 48304 XR_006395664.1 9 0 6 5 68 D3ZVM4 9.13e-29 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Rattus norvegicus (Rat) 3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to organic substance [GO:0071310]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA processing [GO:0035196]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; post-transcriptional regulation of gene expression [GO:0010608]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein metabolic process [GO:0051246]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0001843; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0010608; GO:0016567; GO:0017148; GO:0021915; GO:0030371; GO:0035196; GO:0035198; GO:0035278; GO:0043161; GO:0051246; GO:0051865; GO:0060964; GO:0061158; GO:0061630; GO:0071310; GO:0072089; GO:2000177; GO:2000637 48305 XM_044323177.1 41 0 34 59 81 Q13591 5.79e-51 Semaphorin-5A (Semaphorin-F) (Sema F) Homo sapiens (Human) axon extension [GO:0048675]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell-cell signaling [GO:0007267]; diencephalon development [GO:0021536]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of cell adhesion [GO:0007162]; negative regulation of endothelial cell apoptotic process [GO:2000352]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; positive chemotaxis [GO:0050918]; positive regulation of actin filament depolymerization [GO:0030836]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein kinase B signaling [GO:0051897]; semaphorin-plexin signaling pathway [GO:0071526]; signal clustering [GO:1990256] GO:0001755; GO:0001938; GO:0002043; GO:0005886; GO:0007155; GO:0007162; GO:0007267; GO:0007399; GO:0007411; GO:0007413; GO:0016020; GO:0021536; GO:0030215; GO:0030335; GO:0030836; GO:0035373; GO:0043395; GO:0045499; GO:0045545; GO:0045766; GO:0048675; GO:0048842; GO:0048843; GO:0050918; GO:0051897; GO:0060326; GO:0070062; GO:0071526; GO:0090263; GO:1990256; GO:2000352; GO:2001028 48306 XM_044317104.1 13 29 0 5 0 NA NA NA NA NA NA 48307 XM_044323029.1 141 118 150 199 153 Q9Y238 0 Deleted in lung and esophageal cancer protein 1 (Deleted in lung cancer protein 1) (DLC-1) Homo sapiens (Human) cell differentiation [GO:0030154]; defense response to tumor cell [GO:0002357]; negative regulation of cell population proliferation [GO:0008285]; spermatogenesis [GO:0007283] GO:0002357; GO:0005737; GO:0005829; GO:0005929; GO:0007283; GO:0008285; GO:0015631; GO:0030154; GO:0043014; GO:0048487 48308 XM_044323627.1 0 19 0 1 0 NA NA NA NA NA NA 48309 XR_006391842.1 58 0 29 7 79 NA NA NA NA NA NA 48310 XM_044327384.1 13 5 25 28 30 Q95SX7 9.04e-25 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 48311 XM_044315872.1 0 0 0 1 10 NA NA NA NA NA NA 48312 XM_044312814.1 279 205 225 292 345 Q08CH3 7.92e-70 MPN domain-containing protein (EC 3.4.-.-) Danio rerio (Zebrafish) (Brachydanio rerio) chromatin remodeling [GO:0006338]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteolysis [GO:0006508] GO:0003713; GO:0006338; GO:0006508; GO:0008237; GO:0042393; GO:0045944; GO:0046872 48313 XM_044312814.1 279 205 225 292 345 Q08CH3 3.2e-38 MPN domain-containing protein (EC 3.4.-.-) Danio rerio (Zebrafish) (Brachydanio rerio) chromatin remodeling [GO:0006338]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteolysis [GO:0006508] GO:0003713; GO:0006338; GO:0006508; GO:0008237; GO:0042393; GO:0045944; GO:0046872 48314 XM_029343469.2 55 84 58 64 76 NA NA NA NA NA NA 48315 XR_006397496.1 779 548 586 589 719 NA NA NA NA NA NA 48316 XM_029348792.2 626 341 410 1300 607 Q8BIK4 0 Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin-1) (Zizimin-1) Mus musculus (Mouse) positive regulation of GTPase activity [GO:0043547]; small GTPase mediated signal transduction [GO:0007264] GO:0005085; GO:0007264; GO:0012505; GO:0016020; GO:0031267; GO:0043547 48317 XM_029355780.2 0 0 0 0 322 Q9EQD2 6.05e-35 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 48318 XR_006394764.1 0 6 0 14 0 Q69ZM6 4.49e-180 Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog) Mus musculus (Mouse) axoneme assembly [GO:0035082]; brain development [GO:0007420]; cilium assembly [GO:0060271]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; positive regulation of hh target transcription factor activity [GO:0007228]; positive regulation of smoothened signaling pathway [GO:0045880]; post-embryonic development [GO:0009791]; protein phosphorylation [GO:0006468]; regulation of DNA-binding transcription factor activity [GO:0051090]; smoothened signaling pathway [GO:0007224] GO:0001222; GO:0003351; GO:0004674; GO:0005524; GO:0005576; GO:0005634; GO:0005737; GO:0005829; GO:0005856; GO:0006468; GO:0007224; GO:0007228; GO:0007420; GO:0009791; GO:0035082; GO:0042995; GO:0045880; GO:0046872; GO:0051090; GO:0060271; GO:0106310 48319 XR_003824293.2 0 10 0 3 1 NA NA NA NA NA NA 48320 XM_044321689.1 858 163 386 1273 773 Q5RGV1 0 Inosine-5'-monophosphate dehydrogenase 1b (IMP dehydrogenase 1b) (IMPD 1b) (IMPDH 1b) (EC 1.1.1.205) Danio rerio (Zebrafish) (Brachydanio rerio) GMP biosynthetic process [GO:0006177]; GTP biosynthetic process [GO:0006183] GO:0000166; GO:0003938; GO:0005634; GO:0005737; GO:0006177; GO:0006183; GO:0046872 48321 XR_006394901.1 0 3 70 15 75 NA NA NA NA NA NA 48322 XM_029357266.2 802 689 251 434 406 Q99ND9 1.84e-45 RWD domain-containing protein 1 (Small androgen receptor-interacting protein) Rattus norvegicus (Rat) androgen receptor signaling pathway [GO:0030521]; cellular response to oxidative stress [GO:0034599]; cellular response to testosterone stimulus [GO:0071394]; cytoplasmic translation [GO:0002181]; positive regulation of androgen receptor activity [GO:2000825] GO:0002181; GO:0005737; GO:0005844; GO:0030521; GO:0034599; GO:0071394; GO:2000825 48323 XM_029336904.2 1480 939 463 1098 955 NA NA NA NA NA NA 48324 XM_029325685.2 64 21 81 244 109 NA NA NA NA NA NA 48325 XM_044311741.1 63 34 21 40 61 NA NA NA NA NA NA 48326 XM_044315713.1 3 3 5 18 11 Q3UQ28 1.87e-32 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 48327 XM_044315713.1 3 3 5 18 11 Q3UQ28 2.24e-28 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 48328 XM_044315306.1 1478 1044 862 956 1692 O43290 1.12e-64 U4/U6.U5 tri-snRNP-associated protein 1 (SNU66 homolog) (hSnu66) (Squamous cell carcinoma antigen recognized by T-cells 1) (SART-1) (hSART-1) (U4/U6.U5 tri-snRNP-associated 110 kDa protein) (allergen Hom s 1) Homo sapiens (Human) maturation of 5S rRNA [GO:0000481]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of cytotoxic T cell differentiation [GO:0045585]; spliceosomal snRNP assembly [GO:0000387] GO:0000387; GO:0000398; GO:0000481; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0005794; GO:0005829; GO:0015030; GO:0016607; GO:0045292; GO:0045585; GO:0046540; GO:0071005; GO:0071013 48329 XM_044315306.1 1478 1044 862 956 1692 O43290 6.33e-33 U4/U6.U5 tri-snRNP-associated protein 1 (SNU66 homolog) (hSnu66) (Squamous cell carcinoma antigen recognized by T-cells 1) (SART-1) (hSART-1) (U4/U6.U5 tri-snRNP-associated 110 kDa protein) (allergen Hom s 1) Homo sapiens (Human) maturation of 5S rRNA [GO:0000481]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of cytotoxic T cell differentiation [GO:0045585]; spliceosomal snRNP assembly [GO:0000387] GO:0000387; GO:0000398; GO:0000481; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0005794; GO:0005829; GO:0015030; GO:0016607; GO:0045292; GO:0045585; GO:0046540; GO:0071005; GO:0071013 48330 XR_006398125.1 396 83 161 103 428 Q6PFX9 8.89e-27 Poly [ADP-ribose] polymerase tankyrase-1 (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 5) (ARTD5) (Protein poly-ADP-ribosyltransferase tankyrase-1) (EC 2.4.2.-) (TRF1-interacting ankyrin-related ADP-ribose polymerase 1) (Tankyrase I) (Tankyrase-1) (TANK1) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to nutrient [GO:0031670]; mRNA transport [GO:0051028]; negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric [GO:1904908]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of telomeric DNA binding [GO:1904743]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; protein transport [GO:0015031]; Wnt signaling pathway [GO:0016055] GO:0000139; GO:0000209; GO:0000781; GO:0003950; GO:0005634; GO:0005643; GO:0005654; GO:0005737; GO:0005794; GO:0005815; GO:0005829; GO:0007049; GO:0008270; GO:0015031; GO:0016055; GO:0016604; GO:0016779; GO:0018105; GO:0018107; GO:0031670; GO:0031965; GO:0032212; GO:0042393; GO:0045944; GO:0051028; GO:0051301; GO:0051973; GO:0070198; GO:0070212; GO:0070213; GO:0090263; GO:0097431; GO:1904355; GO:1904357; GO:1904743; GO:1904908; GO:1990404 48331 XR_006396340.1 177 0 213 208 0 NA NA NA NA NA NA 48332 XR_006392523.1 3 1 39 0 102 NA NA NA NA NA NA 48333 XM_029352310.1 2656 2989 1264 1715 1367 P60901 2.59e-151 Proteasome subunit alpha type-6 (Macropain iota chain) (Multicatalytic endopeptidase complex iota chain) (Proteasome iota chain) Rattus norvegicus (Rat) positive regulation of NF-kappaB transcription factor activity [GO:0051092]; proteasomal protein catabolic process [GO:0010498]; proteolysis involved in protein catabolic process [GO:0051603]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000502; GO:0000932; GO:0003723; GO:0005634; GO:0005737; GO:0005839; GO:0005844; GO:0006511; GO:0010498; GO:0016363; GO:0019773; GO:0030016; GO:0030017; GO:0051059; GO:0051092; GO:0051603 48334 XM_044325835.1 2 0 7 7 15 NA NA NA NA NA NA 48335 XR_006392216.1 86 18 34 7 51 NA NA NA NA NA NA 48336 XM_044325621.1 7 30 0 0 81 Q8R4E0 4.79e-42 Interferon regulatory factor 2 (IRF-2) Sigmodon hispidus (Hispid cotton rat) NA GO:0000976; GO:0003700; GO:0005634 48337 XM_044328385.1 266 334 165 328 0 Q9BX70 6.75e-73 BTB/POZ domain-containing protein 2 Homo sapiens (Human) neurogenesis [GO:0022008] GO:0000932; GO:0005829; GO:0022008 48338 XM_029336850.2 32 0 0 37 0 NA NA NA NA NA NA 48339 XM_029347570.2 2 13 0 1 7 NA NA NA NA NA NA 48340 XM_029351912.2 4882 8432 3655 4647 3770 NA NA NA NA NA NA 48341 XR_003826725.2 31 2 2 22 45 NA NA NA NA NA NA 48342 XR_006393328.1 10 22 41 33 33 NA NA NA NA NA NA 48343 XM_029351985.2 806 302 323 756 663 Q6DDH6 1.36e-40 Histone deacetylase complex subunit SAP130-A (130 kDa Sin3-associated polypeptide A) (Sin3-associated polypeptide p130 A) Xenopus laevis (African clawed frog) regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006355 48344 XM_044318892.1 15 0 12 186 0 NA NA NA NA NA NA 48345 XM_029350203.2 0 6 0 0 6 NA NA NA NA NA NA 48346 XM_044329098.1 14 3 0 9 17 NA NA NA NA NA NA 48347 XM_044318278.1 2537 2439 1592 2800 2990 Q7TNV0 8.2e-24 Protein DEK Mus musculus (Mouse) chromatin remodeling [GO:0006338]; positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription by RNA polymerase III [GO:0045945]; regulation of double-strand break repair [GO:2000779]; regulation of double-strand break repair via nonhomologous end joining [GO:2001032] GO:0003677; GO:0005634; GO:0005654; GO:0005730; GO:0006338; GO:0035066; GO:0042393; GO:0043292; GO:0045943; GO:0045944; GO:0045945; GO:0110016; GO:2000779; GO:2001032 48348 XM_029356505.2 28 0 159 0 0 Q3ZBX1 3.24e-92 Phosphatidylinositol N-acetylglucosaminyltransferase subunit C (Phosphatidylinositol-glycan biosynthesis class C protein) (PIG-C) Bos taurus (Bovine) GPI anchor biosynthetic process [GO:0006506] GO:0000506; GO:0006506 48349 XR_006395369.1 0 7 0 199 17 NA NA NA NA NA NA 48350 XR_006395325.1 10 44 39 50 74 NA NA NA NA NA NA 48351 XM_044309796.1 111 92 80 437 67 G8HTB6 3.3e-31 ZP domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 48352 XR_003828256.2 276 124 264 219 127 Q924H0 5.82e-28 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide NPFF receptor) Mus musculus (Mouse) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 48353 XM_044324353.1 49 2 20 42 29 NA NA NA NA NA NA 48354 XM_029357356.2 89 22 0 0 84 NA NA NA NA NA NA 48355 XR_006394293.1 26 8 18 0 83 NA NA NA NA NA NA 48356 XM_044319205.1 47 86 8 60 9 NA NA NA NA NA NA 48357 XR_006394467.1 145 559 110 268 59 NA NA NA NA NA NA 48358 XM_029342169.2 1277 909 658 1176 1361 Q96L93 2.97e-79 Kinesin-like protein KIF16B (Sorting nexin-23) Homo sapiens (Human) early endosome to late endosome transport [GO:0045022]; endoderm development [GO:0007492]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; formation of primary germ layer [GO:0001704]; Golgi to endosome transport [GO:0006895]; microtubule-based movement [GO:0007018]; receptor catabolic process [GO:0032801]; regulation of receptor recycling [GO:0001919] GO:0001704; GO:0001919; GO:0003777; GO:0005524; GO:0005547; GO:0005737; GO:0005768; GO:0005769; GO:0005819; GO:0005829; GO:0005871; GO:0005874; GO:0006895; GO:0007018; GO:0007173; GO:0007492; GO:0008017; GO:0008543; GO:0008574; GO:0016887; GO:0031901; GO:0032266; GO:0032801; GO:0043325; GO:0045022; GO:0080025 48359 XR_003826533.2 8 1 0 18 22 NA NA NA NA NA NA 48360 XM_029323912.2 1001 1625 794 631 744 Q95J75 8.6e-117 Mitochondrial folate transporter/carrier (Solute carrier family 25 member 32) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) folate import into mitochondrion [GO:1904947]; mitochondrial FAD transmembrane transport [GO:1990548]; mitochondrial transport [GO:0006839] GO:0005743; GO:0006839; GO:0008517; GO:1904947; GO:1990548 48361 XM_044312800.1 167 204 94 56 272 NA NA NA NA NA NA 48362 XM_029352519.2 183 134 87 117 223 NA NA NA NA NA NA 48363 XM_044313277.1 341 247 267 366 372 Q96MU7 5.5e-59 YTH domain-containing protein 1 (Splicing factor YT521) (YT521-B) Homo sapiens (Human) dosage compensation by inactivation of X chromosome [GO:0009048]; in utero embryonic development [GO:0001701]; mRNA alternative polyadenylation [GO:0110104]; mRNA export from nucleus [GO:0006406]; mRNA splice site selection [GO:0006376]; mRNA splicing, via spliceosome [GO:0000398]; post-transcriptional regulation of gene expression [GO:0010608]; primary follicle stage [GO:0048160]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of mRNA splicing, via spliceosome [GO:0048024]; spermatogenesis [GO:0007283] GO:0000381; GO:0000398; GO:0001701; GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0005886; GO:0006376; GO:0006406; GO:0007283; GO:0009048; GO:0010608; GO:0016607; GO:0048024; GO:0048160; GO:0110104; GO:1990247 48364 XM_044316856.1 689 651 691 496 620 NA NA NA NA NA NA 48365 XR_006397245.1 3 196 5 13 76 NA NA NA NA NA NA 48366 XM_044328892.1 0 28 0 14 0 Q92793 9.08e-34 CREB-binding protein (Histone lysine acetyltransferase CREBBP) (EC 2.3.1.48) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-) Homo sapiens (Human) cellular response to UV [GO:0034644]; embryonic digit morphogenesis [GO:0042733]; histone acetylation [GO:0016573]; homeostatic process [GO:0042592]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of transcription by RNA polymerase I [GO:0016479]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; protein-containing complex assembly [GO:0065003]; regulation of cellular response to heat [GO:1900034]; regulation of DNA-templated transcription [GO:0006355]; regulation of smoothened signaling pathway [GO:0008589]; response to hypoxia [GO:0001666]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223] GO:0000122; GO:0000123; GO:0000785; GO:0001223; GO:0001666; GO:0002039; GO:0002223; GO:0003682; GO:0003684; GO:0003713; GO:0003714; GO:0004402; GO:0005634; GO:0005654; GO:0005667; GO:0005737; GO:0005829; GO:0006355; GO:0006473; GO:0007165; GO:0008270; GO:0008589; GO:0016407; GO:0016479; GO:0016573; GO:0016604; GO:0018076; GO:0030511; GO:0031490; GO:0031648; GO:0034212; GO:0034644; GO:0042592; GO:0042733; GO:0043426; GO:0045893; GO:0045944; GO:0048511; GO:0061629; GO:0061733; GO:0065003; GO:0140297; GO:1900034 48367 XM_044318821.1 0 0 404 10 0 Q8IVV2 4e-81 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 48368 XM_044318821.1 0 0 404 10 0 Q8IVV2 3.05e-79 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 48369 XM_044318821.1 0 0 404 10 0 Q8IVV2 1.18e-77 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 48370 XM_044318821.1 0 0 404 10 0 Q8IVV2 8.62e-66 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 48371 XM_044318821.1 0 0 404 10 0 Q8IVV2 2.71e-61 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 48372 XM_044318821.1 0 0 404 10 0 Q8IVV2 1.06e-60 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 48373 XM_044318821.1 0 0 404 10 0 Q8IVV2 1.23e-57 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 48374 XM_044318821.1 0 0 404 10 0 Q8IVV2 4.89e-47 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 48375 XR_006391698.1 219 161 276 436 422 NA NA NA NA NA NA 48376 XM_029334095.2 277 293 300 429 388 NA NA NA NA NA NA 48377 XM_044311049.1 0 7 0 0 10 Q99315 3.06e-74 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 48378 XM_044312915.1 322 98 239 376 158 Q5F452 0 Myotubularin-related protein 8 (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64) Gallus gallus (Chicken) negative regulation of autophagy [GO:0010507]; phosphatidylinositol dephosphorylation [GO:0046856] GO:0004438; GO:0005635; GO:0010507; GO:0046856; GO:0052629; GO:0106018 48379 XM_029343619.2 498 188 397 93 277 Q9SZJ2 3.64e-29 Glycine-rich domain-containing protein 2 (AtGRDP2) Arabidopsis thaliana (Mouse-ear cress) auxin-activated signaling pathway [GO:0009734]; cellular response to osmotic stress [GO:0071470]; regulation of auxin mediated signaling pathway [GO:0010928]; regulation of photoperiodism, flowering [GO:2000028] GO:0009734; GO:0010928; GO:0071470; GO:2000028 48380 XM_044317121.1 3537 206 1107 201 234 NA NA NA NA NA NA 48381 XM_044325799.1 390 300 0 295 193 Q5XGF7 2.21e-52 Retinol dehydrogenase 10 (EC 1.1.1.300) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005789; GO:0052650 48382 XM_029340742.2 627 568 413 564 539 Q5Q995 1.18e-30 Protein KRTCAP2 homolog (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit KCP2) (Oligosaccharyl transferase subunit KCP2) Ixodes scapularis (Black-legged tick) (Deer tick) NA GO:0005615; GO:0016020 48383 XM_029328694.2 30 20 24 54 18 NA NA NA NA NA NA 48384 XM_044311976.1 0 0 3 24 0 NA NA NA NA NA NA 48385 XM_029333892.2 0 0 0 0 47 NA NA NA NA NA NA 48386 XR_006397590.1 88 26 10 93 96 NA NA NA NA NA NA 48387 XM_029328900.2 116 67 99 376 272 NA NA NA NA NA NA 48388 XR_006395934.1 140 89 57 45 67 NA NA NA NA NA NA 48389 XM_044311634.1 9 4 17 25 25 NA NA NA NA NA NA 48390 XM_029357253.2 89 31 0 55 83 O43293 4.68e-43 Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like kinase) (Dlk) (MYPT1 kinase) (Zipper-interacting protein kinase) (ZIP-kinase) Homo sapiens (Human) apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cellular response to type II interferon [GO:0071346]; chromatin organization [GO:0006325]; intracellular signal transduction [GO:0035556]; negative regulation of translation [GO:0017148]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of apoptotic process [GO:0042981]; regulation of autophagy [GO:0010506]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of DNA-templated transcription [GO:0006355]; regulation of focal adhesion assembly [GO:0051893]; regulation of mitotic cell cycle [GO:0007346]; regulation of mitotic nuclear division [GO:0007088]; regulation of myosin II filament organization [GO:0043519]; regulation of smooth muscle contraction [GO:0006940] GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006325; GO:0006355; GO:0006468; GO:0006915; GO:0006940; GO:0007088; GO:0007346; GO:0008140; GO:0008360; GO:0010506; GO:0016605; GO:0017148; GO:0030335; GO:0031267; GO:0035556; GO:0042802; GO:0042803; GO:0042981; GO:0043065; GO:0043519; GO:0043522; GO:0046777; GO:0051893; GO:0071346; GO:0090263; GO:0097190; GO:0106310; GO:2000145; GO:2000249 48391 XM_044326341.1 453 315 254 333 425 Q96M69 9.62e-144 Leucine-rich repeat and guanylate kinase domain-containing protein Homo sapiens (Human) axoneme assembly [GO:0035082]; cell differentiation [GO:0030154]; phosphorylation [GO:0016310]; spermatogenesis [GO:0007283] GO:0001669; GO:0002177; GO:0004385; GO:0005524; GO:0005829; GO:0007283; GO:0016310; GO:0030154; GO:0035082; GO:0042995 48392 XM_029348693.2 124 0 28 147 0 NA NA NA NA NA NA 48393 XM_044318170.1 446 383 338 819 540 NA NA NA NA NA NA 48394 XM_029351530.2 57 40 14 58 134 NA NA NA NA NA NA 48395 XM_044320692.1 23 2 0 268 376 O15050 0 TPR and ankyrin repeat-containing protein 1 (Lupus brain antigen 1 homolog) Homo sapiens (Human) NA NA 48396 XM_029338619.2 51895 40398 30356 64583 48333 Q8QG61 0 Cryptochrome-1 Gallus gallus (Chicken) circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; entrainment of circadian clock by photoperiod [GO:0043153]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of protein ubiquitination [GO:0031398]; response to light stimulus [GO:0009416] GO:0003677; GO:0005634; GO:0005737; GO:0005829; GO:0007623; GO:0009416; GO:0009881; GO:0031398; GO:0032922; GO:0042622; GO:0043153; GO:0045721; GO:0045892; GO:0071949; GO:0097381 48397 XM_044308040.1 2 0 0 7 1 NA NA NA NA NA NA 48398 XM_044321595.1 263 0 1071 813 363 Q6NYW6 1.33e-161 CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2) Danio rerio (Zebrafish) (Brachydanio rerio) cell division [GO:0051301]; establishment of mitotic spindle localization [GO:0040001]; exit from mitosis [GO:0010458]; Golgi organization [GO:0007030]; microtubule anchoring [GO:0034453]; microtubule cytoskeleton organization [GO:0000226]; microtubule nucleation [GO:0007020]; microtubule organizing center organization [GO:0031023]; mitotic spindle assembly [GO:0090307]; mitotic spindle organization [GO:0007052]; regulation of microtubule polymerization or depolymerization [GO:0031110]; regulation of microtubule-based process [GO:0032886] GO:0000226; GO:0000776; GO:0005794; GO:0005802; GO:0005815; GO:0005874; GO:0005876; GO:0005881; GO:0007020; GO:0007030; GO:0007052; GO:0008017; GO:0010458; GO:0031023; GO:0031110; GO:0031252; GO:0032587; GO:0032886; GO:0034453; GO:0040001; GO:0045180; GO:0051010; GO:0051301; GO:0072686; GO:0090307 48399 XM_044321595.1 263 0 1071 813 363 Q6NYW6 1.1e-43 CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2) Danio rerio (Zebrafish) (Brachydanio rerio) cell division [GO:0051301]; establishment of mitotic spindle localization [GO:0040001]; exit from mitosis [GO:0010458]; Golgi organization [GO:0007030]; microtubule anchoring [GO:0034453]; microtubule cytoskeleton organization [GO:0000226]; microtubule nucleation [GO:0007020]; microtubule organizing center organization [GO:0031023]; mitotic spindle assembly [GO:0090307]; mitotic spindle organization [GO:0007052]; regulation of microtubule polymerization or depolymerization [GO:0031110]; regulation of microtubule-based process [GO:0032886] GO:0000226; GO:0000776; GO:0005794; GO:0005802; GO:0005815; GO:0005874; GO:0005876; GO:0005881; GO:0007020; GO:0007030; GO:0007052; GO:0008017; GO:0010458; GO:0031023; GO:0031110; GO:0031252; GO:0032587; GO:0032886; GO:0034453; GO:0040001; GO:0045180; GO:0051010; GO:0051301; GO:0072686; GO:0090307 48400 XM_044315379.1 77 48 140 479 235 NA NA NA NA NA NA 48401 XM_044307205.1 587 447 289 501 479 Q8TCS8 0 Polyribonucleotide nucleotidyltransferase 1, mitochondrial (EC 2.7.7.8) (3'-5' RNA exonuclease OLD35) (PNPase old-35) (Polynucleotide phosphorylase 1) (PNPase 1) (Polynucleotide phosphorylase-like protein) Homo sapiens (Human) cellular response to interferon-beta [GO:0035458]; cellular response to oxidative stress [GO:0034599]; liver regeneration [GO:0097421]; mitochondrial mRNA catabolic process [GO:0000958]; mitochondrial mRNA polyadenylation [GO:0097222]; mitochondrial RNA 3'-end processing [GO:0000965]; mitochondrial RNA 5'-end processing [GO:0000964]; mitochondrial RNA catabolic process [GO:0000957]; mitochondrion morphogenesis [GO:0070584]; mRNA catabolic process [GO:0006402]; negative regulation of growth [GO:0045926]; nuclear polyadenylation-dependent mRNA catabolic process [GO:0071042]; positive regulation of miRNA catabolic process [GO:2000627]; positive regulation of mitochondrial RNA catabolic process [GO:0000962]; positive regulation of mRNA catabolic process [GO:0061014]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; regulation of cell cycle [GO:0051726]; regulation of cellular respiration [GO:0043457]; regulation of cellular senescence [GO:2000772]; response to cAMP [GO:0051591]; response to growth hormone [GO:0060416]; RNA catabolic process [GO:0006401]; RNA import into mitochondrion [GO:0035927]; RNA polyadenylation [GO:0043631]; rRNA import into mitochondrion [GO:0035928] GO:0000175; GO:0000957; GO:0000958; GO:0000962; GO:0000964; GO:0000965; GO:0003723; GO:0004654; GO:0005634; GO:0005737; GO:0005739; GO:0005758; GO:0005759; GO:0005789; GO:0005829; GO:0006401; GO:0006402; GO:0008266; GO:0034046; GO:0034599; GO:0035198; GO:0035458; GO:0035927; GO:0035928; GO:0042788; GO:0042802; GO:0043457; GO:0043631; GO:0045025; GO:0045926; GO:0051260; GO:0051591; GO:0051726; GO:0060416; GO:0061014; GO:0070207; GO:0070584; GO:0071042; GO:0097222; GO:0097421; GO:2000627; GO:2000772 48402 XM_029323791.2 40 169 28 54 142 P97292 1.35e-22 Histamine H2 receptor (H2R) (HH2R) (Gastric receptor I) Mus musculus (Mouse) chemical synaptic transmission [GO:0007268]; digestive tract development [GO:0048565]; epithelial cell morphogenesis [GO:0003382]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; gastric acid secretion [GO:0001696]; gastrin-induced gastric acid secretion [GO:0001698]; gland development [GO:0048732]; histamine-induced gastric acid secretion [GO:0001697]; memory [GO:0007613]; negative regulation of arachidonic acid secretion [GO:1900139]; positive regulation of vasoconstriction [GO:0045907]; regulation of synaptic plasticity [GO:0048167]; toxin transport [GO:1901998]; visual learning [GO:0008542] GO:0001696; GO:0001697; GO:0001698; GO:0003382; GO:0004969; GO:0004993; GO:0005886; GO:0007187; GO:0007268; GO:0007613; GO:0008542; GO:0016020; GO:0030425; GO:0030594; GO:0045202; GO:0045907; GO:0048167; GO:0048565; GO:0048732; GO:1900139; GO:1901363; GO:1901998 48403 XR_003825298.2 5 6 2 0 19 NA NA NA NA NA NA 48404 XM_044307315.1 708 374 356 569 713 Q91W36 5.18e-158 Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.4.19.12) (Deubiquitinating enzyme 3) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) Mus musculus (Mouse) chromatin organization [GO:0006325]; DNA repair [GO:0006281]; histone deubiquitination [GO:0016578]; mitotic cell cycle [GO:0000278]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of protein stability [GO:0031647]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000122; GO:0000278; GO:0000785; GO:0000978; GO:0004843; GO:0005634; GO:0005654; GO:0005737; GO:0006281; GO:0006325; GO:0006511; GO:0008270; GO:0016578; GO:0031647; GO:0036464; GO:0042393; GO:0090543; GO:1990841 48405 XM_029331127.2 209 69 147 91 95 NA NA NA NA NA NA 48406 XM_029328698.2 620 239 447 843 593 A6QPF8 8.72e-98 Transmembrane protein 120B Bos taurus (Bovine) fat cell differentiation [GO:0045444]; protein heterooligomerization [GO:0051291] GO:0005637; GO:0016020; GO:0045444; GO:0051291 48407 XM_044306739.1 0 0 12 51 29 NA NA NA NA NA NA 48408 XM_044318535.1 784 1167 410 796 547 Q9UKZ1 0 CCR4-NOT transcription complex subunit 11 Homo sapiens (Human) mRNA catabolic process [GO:0006402]; negative regulation of translation [GO:0017148]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; RNA-mediated gene silencing [GO:0031047] GO:0000289; GO:0005634; GO:0005829; GO:0006402; GO:0017148; GO:0030014; GO:0031047 48409 XR_006393785.1 2 7 2 9 4 NA NA NA NA NA NA 48410 XM_044306799.1 21 19 0 0 50 NA NA NA NA NA NA 48411 XM_044309463.1 44 20 40 83 134 Q15485 6.58e-75 Ficolin-2 (37 kDa elastin-binding protein) (Collagen/fibrinogen domain-containing protein 2) (EBP-37) (Ficolin-B) (Ficolin-beta) (Hucolin) (L-ficolin) (Serum lectin p35) Homo sapiens (Human) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; positive regulation of opsonization [GO:1903028]; proteolysis [GO:0006508]; recognition of apoptotic cell [GO:0043654] GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005576; GO:0005581; GO:0005615; GO:0006508; GO:0008228; GO:0009897; GO:0042802; GO:0043394; GO:0043654; GO:0046872; GO:0048306; GO:0050829; GO:0050830; GO:0062023; GO:0070062; GO:0072562; GO:0097367; GO:1903028; GO:1905370; GO:2001065 48412 XR_006393070.1 41 2 25 5 151 NA NA NA NA NA NA 48413 XM_044309497.1 31 24 92 38 24 NA NA NA NA NA NA 48414 XM_044325271.1 158 52 100 167 181 NA NA NA NA NA NA 48415 XM_029327398.2 115 105 47 0 0 A1A5X5 1.33e-29 Adipolin (Adipose-derived insulin-sensitizing factor) (Complement C1q tumor necrosis factor-related protein 12) Danio rerio (Zebrafish) (Brachydanio rerio) regulation of glucose import [GO:0046324]; Wnt signaling pathway [GO:0016055] GO:0005179; GO:0005576; GO:0005615; GO:0016055; GO:0046324 48416 XM_044328078.1 499 531 117 1364 1290 NA NA NA NA NA NA 48417 XM_029338527.2 13327 8266 6463 11483 9433 O61492 0 Flotillin-2 Drosophila melanogaster (Fruit fly) cell adhesion [GO:0007155]; melanotic encapsulation of foreign target [GO:0035011]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of Wnt protein secretion [GO:0061357]; positive regulation of Wnt signaling pathway by establishment of Wnt protein localization to extracellular region [GO:0035593]; protein localization to plasma membrane [GO:0072659]; regulation of myoblast differentiation [GO:0045661] GO:0005198; GO:0005737; GO:0005829; GO:0005886; GO:0007155; GO:0016600; GO:0031410; GO:0035011; GO:0035593; GO:0045661; GO:0051491; GO:0061357; GO:0072659 48418 XR_006392599.1 76 67 73 97 138 NA NA NA NA NA NA 48419 XM_044327206.1 84 56 55 30 23 NA NA NA NA NA NA 48420 XR_006394460.1 522 217 331 344 295 NA NA NA NA NA NA 48421 XM_044313996.1 0 15 9 3 2 NA NA NA NA NA NA 48422 XM_044307691.1 158 724 83 765 435 NA NA NA NA NA NA 48423 XM_029339600.2 32 14 0 16 17 Q9W676 9.48e-127 LIM domain-binding protein 2 (LDB-2) (Carboxyl-terminal LIM domain-binding protein 1) (CLIM-1) (LIM domain-binding factor CLIM1) (cLdb2) Gallus gallus (Chicken) negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000122; GO:0005634; GO:0005667; GO:0007399; GO:0030274; GO:0045944 48424 XM_044310048.1 0 231 44 0 71 Q28824 5.32e-75 Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form] Bos taurus (Bovine) protein phosphorylation [GO:0006468]; tonic smooth muscle contraction [GO:0014820] GO:0001725; GO:0003779; GO:0004672; GO:0004687; GO:0005516; GO:0005524; GO:0005737; GO:0006468; GO:0014820; GO:0030027; GO:0032154; GO:0046872 48425 XM_029335208.2 243 164 167 221 210 NA NA NA NA NA NA 48426 XM_029345280.2 28 392 129 170 378 NA NA NA NA NA NA 48427 XM_044321849.1 103 96 13 134 42 NA NA NA NA NA NA 48428 XM_044309439.1 0 0 0 6 9 NA NA NA NA NA NA 48429 XM_044313787.1 3 55 16 19 97 NA NA NA NA NA NA 48430 XM_044322152.1 0 6 0 0 0 NA NA NA NA NA NA 48431 XM_029343452.2 0 27 82 622 95 Q60HF3 5.88e-36 BLOC-3 complex member HPS1 (Hermansky-Pudlak syndrome 1 protein homolog) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) melanosome assembly [GO:1903232]; vesicle-mediated transport [GO:0016192] GO:0005085; GO:0016192; GO:0031085; GO:1903232 48432 XM_029343452.2 0 27 82 622 95 Q60HF3 1.31e-27 BLOC-3 complex member HPS1 (Hermansky-Pudlak syndrome 1 protein homolog) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) melanosome assembly [GO:1903232]; vesicle-mediated transport [GO:0016192] GO:0005085; GO:0016192; GO:0031085; GO:1903232 48433 XM_044311515.1 0 0 13 34 0 NA NA NA NA NA NA 48434 XR_006393031.1 2 3 28 3 25 NA NA NA NA NA NA 48435 XR_003825317.2 16 16 16 11 33 NA NA NA NA NA NA 48436 XM_029343118.2 72 19 0 0 0 Q9Z351 3.77e-68 Potassium voltage-gated channel subfamily KQT member 2 (KQT-like 2) (Potassium channel subunit alpha KvLQT2) (Voltage-gated potassium channel subunit Kv7.2) Mus musculus (Mouse) potassium ion transmembrane transport [GO:0071805]; regulation of ion transmembrane transport [GO:0034765]; transmission of nerve impulse [GO:0019226] GO:0005244; GO:0005249; GO:0005251; GO:0005516; GO:0005886; GO:0008076; GO:0009986; GO:0016020; GO:0019226; GO:0030506; GO:0032991; GO:0033268; GO:0034765; GO:0043194; GO:0047485; GO:0071805 48437 XM_044319888.1 28 79 273 173 96 Q6NXR0 8.88e-50 Interferon-inducible GTPase 5 (EC 3.6.5.-) (Immunity-related GTPase cinema 1) Homo sapiens (Human) cellular response to interferon-beta [GO:0035458]; defense response [GO:0006952] GO:0003924; GO:0005525; GO:0005789; GO:0006952; GO:0035458 48438 XM_044321228.1 311 393 214 461 295 A3KQV2 3.49e-26 BRO1 domain-containing protein BROX (BRO1 domain- and CAAX motif-containing protein) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0016020 48439 XM_044310392.1 112 62 19 60 39 Q8VHE6 5.36e-45 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5) Mus musculus (Mouse) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0003777; GO:0005524; GO:0005576; GO:0005737; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 48440 XM_029340232.2 39472 33345 11141 19683 26341 NA NA NA NA NA NA 48441 XM_029351872.2 9 0 0 0 17 Q56X76 8.84e-71 DEAD-box ATP-dependent RNA helicase 39 (EC 3.6.4.13) Arabidopsis thaliana (Mouse-ear cress) chloroplast rRNA processing [GO:1901259]; mitochondrial large ribosomal subunit assembly [GO:1902775]; ribulose bisphosphate carboxylase complex assembly [GO:0110102] GO:0003724; GO:0003729; GO:0005524; GO:0005739; GO:0009507; GO:0016887; GO:0070180; GO:0110102; GO:1901259; GO:1902775 48442 XM_044319478.1 1416 621 388 979 12 NA NA NA NA NA NA 48443 XM_029344453.2 2927 3838 1477 2948 4045 NA NA NA NA NA NA 48444 XM_029353553.2 839 541 374 661 696 Q4R4T9 3.82e-38 Ran-binding protein 3 (RanBP3) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) intracellular transport [GO:0046907]; protein transport [GO:0015031] GO:0005634; GO:0005737; GO:0015031; GO:0046907 48445 XM_044328504.1 33 21 4 4 9 Q8K2J9 1.87e-74 BTB/POZ domain-containing protein 6 Mus musculus (Mouse) neurogenesis [GO:0022008] GO:0005829; GO:0022008 48446 XM_029357788.2 9 12 0 0 0 Q9EQD2 5.14e-46 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 48447 XM_029323644.2 2151 2695 2584 1644 1831 P34642 1.07e-22 Signal recognition particle 9 kDa protein (SRP9) Caenorhabditis elegans negative regulation of translational elongation [GO:0045900]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614] GO:0005786; GO:0006614; GO:0008312; GO:0045900 48448 XM_029338390.2 142 102 40 129 318 NA NA NA NA NA NA 48449 XM_029331172.2 1293 837 794 1237 1460 E7F1U2 2.42e-92 Dynamin-binding protein (Scaffold protein Tuba) Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; intracellular signal transduction [GO:0035556]; kidney development [GO:0001822] GO:0001822; GO:0005085; GO:0005794; GO:0005795; GO:0005856; GO:0005911; GO:0035556; GO:0045202; GO:0060271; GO:0098793 48450 XR_006395115.1 151 22 0 2 0 NA NA NA NA NA NA 48451 XM_029337584.2 0 104 73 27 134 Q9BT88 4.88e-42 Synaptotagmin-11 (Synaptotagmin XI) (SytXI) Homo sapiens (Human) autophagy [GO:0006914]; calcium ion regulated lysosome exocytosis [GO:1990927]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; establishment of vesicle localization [GO:0051650]; learning [GO:0007612]; memory [GO:0007613]; negative regulation of cytokine production [GO:0001818]; negative regulation of dopamine secretion [GO:0033602]; negative regulation of endocytosis [GO:0045806]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of microglial cell activation [GO:1903979]; negative regulation of neurotransmitter secretion [GO:0046929]; negative regulation of phagocytosis [GO:0050765]; negative regulation of tumor necrosis factor production [GO:0032720]; plasma membrane repair [GO:0001778]; positive regulation of protein localization to phagocytic vesicle [GO:1905171]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of defense response to bacterium [GO:1900424]; regulation of dopamine secretion [GO:0014059]; regulation of phagosome maturation [GO:1905162]; regulation of synaptic vesicle endocytosis [GO:1900242]; vesicle fusion [GO:0006906]; vesicle-mediated transport [GO:0016192] GO:0000149; GO:0001778; GO:0001786; GO:0001818; GO:0001891; GO:0005509; GO:0005544; GO:0005764; GO:0005765; GO:0005802; GO:0005886; GO:0006906; GO:0006914; GO:0007612; GO:0007613; GO:0008021; GO:0014059; GO:0014069; GO:0016192; GO:0017156; GO:0017158; GO:0030276; GO:0030424; GO:0030425; GO:0030665; GO:0031369; GO:0031625; GO:0031982; GO:0032009; GO:0032715; GO:0032720; GO:0033602; GO:0042802; GO:0043005; GO:0043197; GO:0043204; GO:0045202; GO:0045335; GO:0045806; GO:0046929; GO:0048487; GO:0048787; GO:0050765; GO:0051650; GO:0055037; GO:0055038; GO:0060076; GO:0060077; GO:0070382; GO:0071277; GO:0098691; GO:0098793; GO:1900242; GO:1900424; GO:1903979; GO:1905162; GO:1905171; GO:1990927 48452 XM_029355165.2 5 0 41 0 2 NA NA NA NA NA NA 48453 XM_044324378.1 497 506 437 362 431 Q96ME1 2.91e-25 F-box/LRR-repeat protein 18 (F-box and leucine-rich repeat protein 18) Homo sapiens (Human) SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0005829; GO:0019005; GO:0031146 48454 XM_044321633.1 106 61 146 0 20 P49914 2.9e-71 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) (5,10-methenyl-tetrahydrofolate synthetase) (MTHFS) (Methenyl-THF synthetase) Homo sapiens (Human) folic acid catabolic process [GO:0046657]; folic acid metabolic process [GO:0046655]; folic acid-containing compound biosynthetic process [GO:0009396]; formate metabolic process [GO:0015942]; glutamate metabolic process [GO:0006536]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653] GO:0005524; GO:0005542; GO:0005737; GO:0005739; GO:0005759; GO:0005829; GO:0006536; GO:0009396; GO:0015942; GO:0030272; GO:0035999; GO:0046653; GO:0046655; GO:0046657; GO:0046872 48455 XM_029341605.2 352 268 177 379 380 Q0P5I5 8.58e-121 4-hydroxy-2-oxoglutarate aldolase, mitochondrial (EC 4.1.3.16) (Dihydrodipicolinate synthase-like) (DHDPS-like protein) (Probable 2-keto-4-hydroxyglutarate aldolase) (Probable KHG-aldolase) Bos taurus (Bovine) glyoxylate catabolic process [GO:0009436] GO:0005739; GO:0008700; GO:0009436; GO:0106009 48456 XM_029339634.2 8775 14664 7131 8619 7874 A7SXK3 6.2e-115 Transmembrane emp24 domain-containing protein Nematostella vectensis (Starlet sea anemone) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886] GO:0005783; GO:0005793; GO:0005794; GO:0006886; GO:0006888; GO:0007030; GO:0030134; GO:0030659 48457 XM_044321811.1 0 0 0 0 20 NA NA NA NA NA NA 48458 XM_044326833.1 8 38 24 19 29 Q16445 1.35e-66 Gamma-aminobutyric acid receptor subunit alpha-6 (GABA(A) receptor subunit alpha-6) Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid signaling pathway [GO:0007214]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; regulation of postsynaptic membrane potential [GO:0060078]; signal transduction [GO:0007165]; synaptic transmission, GABAergic [GO:0051932] GO:0004890; GO:0005231; GO:0005237; GO:0005886; GO:0007165; GO:0007214; GO:0007268; GO:0008503; GO:0022851; GO:0030594; GO:0032590; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051932; GO:0060078; GO:0098794; GO:0099192; GO:1902476; GO:1902711; GO:1904315 48459 XM_029333470.2 495 159 255 454 263 NA NA NA NA NA NA 48460 XM_029335694.2 1119 872 855 1622 1348 Q8CGE9 5.54e-28 Regulator of G-protein signaling 12 (RGS12) Mus musculus (Mouse) regulation of G protein-coupled receptor signaling pathway [GO:0008277]; signal transduction [GO:0007165]; termination of G protein-coupled receptor signaling pathway [GO:0038032] GO:0001965; GO:0005096; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0005886; GO:0007165; GO:0008277; GO:0030425; GO:0030695; GO:0032991; GO:0038032; GO:0043025; GO:0045202; GO:0097440 48461 XM_029335694.2 1119 872 855 1622 1348 Q8CGE9 6.16e-27 Regulator of G-protein signaling 12 (RGS12) Mus musculus (Mouse) regulation of G protein-coupled receptor signaling pathway [GO:0008277]; signal transduction [GO:0007165]; termination of G protein-coupled receptor signaling pathway [GO:0038032] GO:0001965; GO:0005096; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0005886; GO:0007165; GO:0008277; GO:0030425; GO:0030695; GO:0032991; GO:0038032; GO:0043025; GO:0045202; GO:0097440 48462 XM_029350625.2 135 130 124 248 239 Q6PF45 1.2e-54 Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Solute carrier family 32 member 1) (Vesicular GABA transporter) (xVIAAT) Xenopus laevis (African clawed frog) beta-alanine transport [GO:0001762]; gamma-aminobutyric acid import [GO:0051939]; gamma-aminobutyric acid transport [GO:0015812]; glycine transport [GO:0015816]; neurotransmitter transport [GO:0006836] GO:0001762; GO:0006836; GO:0008021; GO:0015185; GO:0015187; GO:0015812; GO:0015816; GO:0030659; GO:0042995; GO:0051939; GO:0098793; GO:0140799; GO:0140800 48463 XM_029334625.2 108 54 79 42 78 NA NA NA NA NA NA 48464 XM_044322971.1 172 571 0 611 390 Q9Y6R4 1.34e-36 Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAP three kinase 1) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4) Homo sapiens (Human) chorionic trophoblast cell differentiation [GO:0060718]; intracellular signal transduction [GO:0035556]; male germ-line sex determination [GO:0019100]; MAPK cascade [GO:0000165]; placenta development [GO:0001890]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein phosphorylation [GO:0006468]; regulation of gene expression [GO:0010468]; response to UV-C [GO:0010225] GO:0000165; GO:0001890; GO:0004709; GO:0005524; GO:0005737; GO:0006468; GO:0010225; GO:0010468; GO:0019100; GO:0032212; GO:0035556; GO:0043507; GO:0046872; GO:0048471; GO:0051973; GO:0060718; GO:0106310; GO:1900745; GO:1904355 48465 XM_029335223.2 574 662 581 942 1285 NA NA NA NA NA NA 48466 XM_044313760.1 17 3 13 1 6 NA NA NA NA NA NA 48467 XM_044310197.1 10 0 4 11 31 Q80XJ3 1.24e-49 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 48468 XM_044310197.1 10 0 4 11 31 Q80XJ3 7.04e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 48469 XM_044310197.1 10 0 4 11 31 Q80XJ3 7.81e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 48470 XM_044310197.1 10 0 4 11 31 Q80XJ3 1.11e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 48471 XM_044310197.1 10 0 4 11 31 Q80XJ3 1.75e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 48472 XM_044310197.1 10 0 4 11 31 Q80XJ3 4.44e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 48473 XM_044310197.1 10 0 4 11 31 Q80XJ3 1.64e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 48474 XM_044310197.1 10 0 4 11 31 Q80XJ3 4.39e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 48475 XM_044310197.1 10 0 4 11 31 Q80XJ3 9.83e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 48476 XM_044310197.1 10 0 4 11 31 Q80XJ3 2.95e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 48477 XM_029339036.2 75 64 16 108 31 Q0VA77 8.24e-87 Bis(5'-adenosyl)-triphosphatase enpp4 (EC 3.6.1.29) (AP3A hydrolase) (AP3Aase) (Ectonucleotide pyrophosphatase/phosphodiesterase family member 4) (E-NPP 4) (NPP-4) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) blood coagulation [GO:0007596] GO:0005886; GO:0007596; GO:0046872; GO:0047710 48478 XM_044317268.1 266 231 164 186 165 Q8IY21 0 Probable ATP-dependent RNA helicase DDX60 (EC 3.6.4.13) (DEAD box protein 60) Homo sapiens (Human) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; response to virus [GO:0009615] GO:0003690; GO:0003724; GO:0003725; GO:0003727; GO:0005524; GO:0005737; GO:0005829; GO:0009615; GO:0016887; GO:0045087; GO:0045111; GO:0051607; GO:1900245; GO:1900246 48479 XM_044310219.1 0 0 11 0 4 NA NA NA NA NA NA 48480 XM_044326298.1 35 31 2 17 11 P02469 1.13e-92 Laminin subunit beta-1 (Laminin B1 chain) (Laminin-1 subunit beta) (Laminin-10 subunit beta) (Laminin-12 subunit beta) (Laminin-2 subunit beta) (Laminin-6 subunit beta) (Laminin-8 subunit beta) Mus musculus (Mouse) animal organ morphogenesis [GO:0009887]; basement membrane assembly [GO:0070831]; cell migration [GO:0016477]; embryo implantation [GO:0007566]; learning or memory [GO:0007611]; negative regulation of cell adhesion [GO:0007162]; neuron projection development [GO:0031175]; neuronal-glial interaction involved in cerebral cortex radial glia guided migration [GO:0021812]; odontogenesis [GO:0042476]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of muscle cell differentiation [GO:0051149]; regulation of basement membrane organization [GO:0110011]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888] GO:0005178; GO:0005201; GO:0005576; GO:0005604; GO:0005606; GO:0005607; GO:0005615; GO:0005634; GO:0007162; GO:0007566; GO:0007611; GO:0009887; GO:0009888; GO:0016477; GO:0019899; GO:0021812; GO:0030335; GO:0031012; GO:0031175; GO:0034446; GO:0042476; GO:0043208; GO:0043256; GO:0043257; GO:0043259; GO:0045785; GO:0048471; GO:0051149; GO:0062023; GO:0070831; GO:0098637; GO:0110011; GO:2001046 48481 XM_044321966.1 59 0 0 0 261 Q9UA35 1.73e-146 Solute carrier family 28 member 3 (Concentrative Na(+)-nucleoside cotransporter 3) (hfCNT) Eptatretus stoutii (Pacific hagfish) NA GO:0005337; GO:0005886; GO:0015293 48482 XM_029339179.2 1140 475 516 1184 847 NA NA NA NA NA NA 48483 XM_029342134.2 0 16 0 0 3 Q810T5 2.35e-89 Histone acetyltransferase KAT7 (EC 2.3.1.48) (Histone acetyltransferase binding to ORC1) (Lysine acetyltransferase 7) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (MYST-2) Rattus norvegicus (Rat) DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication-dependent chromatin disassembly [GO:0140889]; histone H3 acetylation [GO:0043966]; histone H3-K14 acetylation [GO:0044154]; histone H4 acetylation [GO:0043967]; histone H4-K12 acetylation [GO:0043983]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; histone modification [GO:0016570]; internal peptidyl-lysine acetylation [GO:0018393]; natural killer cell differentiation [GO:0001779]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of DNA replication [GO:0045740]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of histone H4 acetylation [GO:0090240]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of cell cycle [GO:0051726]; regulation of cell growth [GO:0001558]; regulation of DNA biosynthetic process [GO:2000278]; regulation of DNA replication [GO:0006275]; regulation of DNA-templated DNA replication initiation [GO:0030174]; regulation of DNA-templated transcription [GO:0006355]; regulation of nucleotide-excision repair [GO:2000819]; response to actinomycin D [GO:0072716]; response to anisomycin [GO:0072739]; response to dithiothreitol [GO:0072720]; response to hydroxyurea [GO:0072710]; response to sorbitol [GO:0072708]; stress-activated protein kinase signaling cascade [GO:0031098]; T cell differentiation [GO:0030217]; transcription initiation-coupled chromatin remodeling [GO:0045815] GO:0000123; GO:0000775; GO:0001558; GO:0001779; GO:0003688; GO:0003712; GO:0004402; GO:0005634; GO:0005654; GO:0005694; GO:0005829; GO:0006260; GO:0006275; GO:0006281; GO:0006355; GO:0008270; GO:0010485; GO:0016570; GO:0018393; GO:0030174; GO:0030217; GO:0031098; GO:0032786; GO:0036408; GO:0036409; GO:0042393; GO:0043161; GO:0043966; GO:0043967; GO:0043981; GO:0043982; GO:0043983; GO:0043994; GO:0043995; GO:0043996; GO:0043997; GO:0044016; GO:0044154; GO:0045648; GO:0045740; GO:0045815; GO:0045892; GO:0045944; GO:0051726; GO:0072708; GO:0072710; GO:0072716; GO:0072720; GO:0072739; GO:0090240; GO:0090734; GO:0140889; GO:1900182; GO:1902035; GO:2000278; GO:2000819 48484 XR_006394919.1 0 11 7 20 10 NA NA NA NA NA NA 48485 XM_044316827.1 138 11 24 46 101 NA NA NA NA NA NA 48486 XM_029331045.2 782 905 510 910 870 Q6P3Z3 1.1e-38 Peroxynitrite isomerase THAP4 (EC 5.99.-.-) (Ferric nitrobindin) (Nb(III)) (THAP domain-containing protein 4) Mus musculus (Mouse) nitrate metabolic process [GO:0042126]; tyrosine metabolic process [GO:0006570] GO:0003677; GO:0005634; GO:0005737; GO:0006570; GO:0020037; GO:0042126; GO:0042802; GO:0046872; GO:0062213; GO:0070026 48487 XM_044307133.1 34 11 6 3 39 Q9P2E3 0 NFX1-type zinc finger-containing protein 1 Homo sapiens (Human) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 48488 XM_029356778.2 0 285 0 0 405 Q5ZJ43 2.19e-129 Exocyst complex component 8 Gallus gallus (Chicken) exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; protein localization [GO:0008104]; protein transport [GO:0015031] GO:0000145; GO:0006887; GO:0006893; GO:0008104; GO:0015031; GO:0030426; GO:0048471 48489 XM_044309648.1 347 116 188 241 59 A0A3M6TIF0 0 NA NA NA NA 48490 XR_006394481.1 668 688 204 411 385 NA NA NA NA NA NA 48491 XM_029333888.2 1236 1448 898 1413 1117 Q04841 1.79e-66 DNA-3-methyladenine glycosylase (EC 3.2.2.21) (3-alkyladenine DNA glycosylase) (3-methyladenine DNA glycosidase) (ADPG) (N-methylpurine-DNA glycosylase) Mus musculus (Mouse) base-excision repair [GO:0006284] GO:0003677; GO:0003905; GO:0005654; GO:0005829; GO:0006284; GO:0008725; GO:0042645; GO:0043916; GO:0052821; GO:0052822 48492 XM_029351067.2 53 0 12 0 35 Q9VCY8 9.93e-93 Adiponectin receptor protein Drosophila melanogaster (Fruit fly) adiponectin-activated signaling pathway [GO:0033211]; fatty acid oxidation [GO:0019395]; female germ-line stem cell population maintenance [GO:0036099]; glucose homeostasis [GO:0042593]; hormone-mediated signaling pathway [GO:0009755]; positive regulation of insulin secretion [GO:0032024]; triglyceride homeostasis [GO:0070328] GO:0005886; GO:0009755; GO:0016020; GO:0016500; GO:0019395; GO:0032024; GO:0033211; GO:0036099; GO:0038023; GO:0042593; GO:0046872; GO:0070328 48493 XM_044320735.1 9 6 0 0 0 Q09575 1.13e-25 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 48494 XM_029346072.2 666 722 632 918 1215 Q6DJA3 7.17e-123 Damage-control phosphatase ARMT1 (EC 3.1.3.-) (Acidic residue methyltransferase 1) (Protein-glutamate O-methyltransferase) (EC 2.1.1.-) (Sugar phosphate phosphatase ARMT1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) methylation [GO:0032259]; regulation of response to DNA damage stimulus [GO:2001020] GO:0008757; GO:0008983; GO:0032259; GO:0046872; GO:0051998; GO:0097023; GO:0103026; GO:2001020 48495 XM_044326385.1 3002 2158 1388 1879 2028 Q00537 0 Cyclin-dependent kinase 17 (EC 2.7.11.22) (Cell division protein kinase 17) (PCTAIRE-motif protein kinase 2) (Serine/threonine-protein kinase PCTAIRE-2) Homo sapiens (Human) protein phosphorylation [GO:0006468]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083] GO:0000083; GO:0004672; GO:0004693; GO:0005524; GO:0005634; GO:0005737; GO:0006468; GO:0106310 48496 XM_044321243.1 33 0 18 1 10 P50293 5.86e-26 Arylamine N-acetyltransferase 2 (EC 2.3.1.5) (Arylamide acetylase 2) (N-acetyltransferase type 2) (AT-2) (NAT-2) (Polymorphic arylamine N-acetyltransferase) (PNAT) Mesocricetus auratus (Golden hamster) NA GO:0004060; GO:0005737 48497 XM_029341861.2 12 488 0 105 803 NA NA NA NA NA NA 48498 XM_029341503.2 30 0 0 0 12 NA NA NA NA NA NA 48499 XM_044321052.1 1180 610 680 822 549 NA NA NA NA NA NA 48500 XM_044310207.1 40 6 35 12 152 NA NA NA NA NA NA 48501 XM_044311307.1 22 0 0 4 9 Q91W78 2.76e-41 U6 snRNA phosphodiesterase 1 (3'-5' RNA exonuclease USB1) (EC 4.6.1.-) Mus musculus (Mouse) RNA splicing [GO:0008380]; snRNA 3'-end processing [GO:0034472]; U6 snRNA 3'-end processing [GO:0034477] GO:0000175; GO:0005634; GO:0005654; GO:0008380; GO:0016829; GO:0034472; GO:0034477; GO:0045171; GO:1990838 48502 XM_044313085.1 94 43 20 159 82 Q7RTR2 7.22e-59 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 48503 XM_044313085.1 94 43 20 159 82 Q7RTR2 7.81e-57 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 48504 XM_044313706.1 0 0 46 0 0 Q9W735 1.52e-86 Prominin-1-A (Prominin-like protein 1) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005783; GO:0005793; GO:0005886; GO:0005902; GO:0005929; GO:0009986; GO:0015485; GO:0016324; GO:0031528; GO:0071914 48505 XM_029336424.2 0 42 0 75 0 Q6ZNB5 4.17e-33 Protein XNDC1N (XRCC1 N-terminal domain-containing 1 N-terminal like) Homo sapiens (Human) single strand break repair [GO:0000012] GO:0000012; GO:0003684; GO:0005694; GO:0005730 48506 XM_029349323.2 5435 3823 3525 6518 5593 P08110 0 Endoplasmin (Heat shock 108 kDa protein) (HSP 108) (HSP108) (Heat shock protein 90 kDa beta member 1) (Transferrin-binding protein) Gallus gallus (Chicken) intracellular sequestering of iron ion [GO:0006880]; protein folding [GO:0006457]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0005524; GO:0005783; GO:0006457; GO:0006880; GO:0016887; GO:0030433; GO:0033018; GO:0042470; GO:0048471; GO:0051082; GO:0140662 48507 XM_029349323.2 5435 3823 3525 6518 5593 P08110 2.01e-122 Endoplasmin (Heat shock 108 kDa protein) (HSP 108) (HSP108) (Heat shock protein 90 kDa beta member 1) (Transferrin-binding protein) Gallus gallus (Chicken) intracellular sequestering of iron ion [GO:0006880]; protein folding [GO:0006457]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0005524; GO:0005783; GO:0006457; GO:0006880; GO:0016887; GO:0030433; GO:0033018; GO:0042470; GO:0048471; GO:0051082; GO:0140662 48508 XM_044317230.1 0 0 11 45 27 O54991 3.26e-36 Contactin-associated protein 1 (Caspr) (Caspr1) (MHDNIV) (NCP1) (Neurexin IV) (Neurexin-4) (Paranodin) Mus musculus (Mouse) axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cytoskeleton organization [GO:0007010]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process [GO:0050905]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuronal action potential propagation [GO:0019227]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; postsynaptic density organization [GO:0097106]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; regulation of synapse maturation [GO:0090128] GO:0002175; GO:0005886; GO:0005918; GO:0007005; GO:0007010; GO:0007155; GO:0007409; GO:0016020; GO:0017124; GO:0019227; GO:0022010; GO:0022011; GO:0030424; GO:0030913; GO:0031175; GO:0033010; GO:0033270; GO:0042552; GO:0043209; GO:0048786; GO:0048812; GO:0050884; GO:0050885; GO:0050905; GO:0071205; GO:0090128; GO:0097106; GO:0098529; GO:0098978; GO:1990227 48509 XM_029351957.2 313 131 105 183 26 Q06546 3.48e-59 GA-binding protein alpha chain (GABP subunit alpha) (Nuclear respiratory factor 2 subunit alpha) (Transcription factor E4TF1-60) Homo sapiens (Human) blastocyst formation [GO:0001825]; cell differentiation [GO:0030154]; cellular response to dopamine [GO:1903351]; negative regulation of megakaryocyte differentiation [GO:0045653]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000785; GO:0000976; GO:0000978; GO:0000981; GO:0001228; GO:0001825; GO:0003682; GO:0003700; GO:0005634; GO:0005654; GO:0006357; GO:0010628; GO:0030154; GO:0045653; GO:0045944; GO:1903351; GO:1990837 48510 XM_029341889.2 0 71 0 69 0 P35224 0 Catenin beta (Beta-catenin) Urechis caupo (Innkeeper worm) (Spoonworm) cell adhesion [GO:0007155] GO:0005737; GO:0005856; GO:0007155; GO:0045296 48511 XM_044328293.1 52 31 17 63 27 NA NA NA NA NA NA 48512 XM_044319521.1 18 0 0 0 0 NA NA NA NA NA NA 48513 XM_029328012.2 1541 1235 375 1228 1443 Q803V5 6.58e-171 Target of rapamycin complex subunit lst8 (TORC subunit lst8) (G protein beta subunit-like) (Gable) (Protein GbetaL) (MTOR associated protein, LST8 homolog) Danio rerio (Zebrafish) (Brachydanio rerio) regulation of actin cytoskeleton organization [GO:0032956]; TOR signaling [GO:0031929] GO:0005737; GO:0031929; GO:0031931; GO:0031932; GO:0032956 48514 XR_003823305.2 82 77 30 58 114 NA NA NA NA NA NA 48515 XM_044322456.1 4 33 0 14 32 Q80XJ3 1.17e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 48516 XM_044322456.1 4 33 0 14 32 Q80XJ3 4.29e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 48517 XM_044322456.1 4 33 0 14 32 Q80XJ3 9.53e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 48518 XM_044322456.1 4 33 0 14 32 Q80XJ3 2.53e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 48519 XM_044322456.1 4 33 0 14 32 Q80XJ3 1.1e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 48520 XM_044322456.1 4 33 0 14 32 Q80XJ3 2.12e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 48521 XM_044322456.1 4 33 0 14 32 Q80XJ3 1.84e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 48522 XM_044322456.1 4 33 0 14 32 Q80XJ3 7.01e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 48523 XM_044322456.1 4 33 0 14 32 Q80XJ3 1.13e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 48524 XM_044322456.1 4 33 0 14 32 Q80XJ3 4.85e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 48525 XM_044322456.1 4 33 0 14 32 Q80XJ3 1.68e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 48526 XM_044316420.1 49 16 27 66 55 Q91ZI0 1.42e-33 Cadherin EGF LAG seven-pass G-type receptor 3 Mus musculus (Mouse) axonal fasciculation [GO:0007413]; cell-cell adhesion [GO:0098609]; cilium assembly [GO:0060271]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; planar cell polarity pathway involved in axon guidance [GO:1904938]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] GO:0001932; GO:0004930; GO:0005509; GO:0005886; GO:0007156; GO:0007413; GO:0032880; GO:0036514; GO:0036515; GO:0060271; GO:0097475; GO:0098609; GO:1904938 48527 XM_044316420.1 49 16 27 66 55 Q91ZI0 2.77e-23 Cadherin EGF LAG seven-pass G-type receptor 3 Mus musculus (Mouse) axonal fasciculation [GO:0007413]; cell-cell adhesion [GO:0098609]; cilium assembly [GO:0060271]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; planar cell polarity pathway involved in axon guidance [GO:1904938]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] GO:0001932; GO:0004930; GO:0005509; GO:0005886; GO:0007156; GO:0007413; GO:0032880; GO:0036514; GO:0036515; GO:0060271; GO:0097475; GO:0098609; GO:1904938 48528 XM_044314417.1 0 19 7 7 43 NA NA NA NA NA NA 48529 XR_003825985.2 14 47 6 7 27 NA NA NA NA NA NA 48530 XM_029357856.2 4527 1654 3080 4462 3807 Q8N0W3 0 L-fucose kinase (Fucokinase) (EC 2.7.1.52) Homo sapiens (Human) carbohydrate phosphorylation [GO:0046835]; GDP-L-fucose salvage [GO:0042352]; response to dopamine [GO:1903350] GO:0005524; GO:0005829; GO:0042352; GO:0046835; GO:0050201; GO:1903350 48531 XM_044320476.1 2722 2231 1693 3667 3114 NA NA NA NA NA NA 48532 XM_044317298.1 4 0 16 20 28 NA NA NA NA NA NA 48533 XR_006395452.1 6 42 31 17 22 NA NA NA NA NA NA 48534 XM_029329300.2 791 738 375 574 584 Q99873 0 Protein arginine N-methyltransferase 1 (EC 2.1.1.319) (Histone-arginine N-methyltransferase PRMT1) (Interferon receptor 1-bound protein 4) Homo sapiens (Human) cardiac muscle tissue development [GO:0048738]; cell surface receptor signaling pathway [GO:0007166]; histone H4-R3 methylation [GO:0043985]; in utero embryonic development [GO:0001701]; negative regulation of JNK cascade [GO:0046329]; negative regulation of megakaryocyte differentiation [GO:0045653]; neuron projection development [GO:0031175]; peptidyl-arginine methylation [GO:0018216]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of hemoglobin biosynthetic process [GO:0046985]; positive regulation of p38MAPK cascade [GO:1900745]; protein homooligomerization [GO:0051260]; protein methylation [GO:0006479]; regulation of megakaryocyte differentiation [GO:0045652]; RNA splicing [GO:0008380]; viral protein processing [GO:0019082] GO:0001701; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006479; GO:0007166; GO:0008168; GO:0008170; GO:0008276; GO:0008284; GO:0008327; GO:0008380; GO:0016274; GO:0018216; GO:0019082; GO:0019899; GO:0031175; GO:0034709; GO:0035241; GO:0035242; GO:0042054; GO:0042802; GO:0043985; GO:0044020; GO:0045648; GO:0045652; GO:0045653; GO:0046329; GO:0046985; GO:0048273; GO:0048738; GO:0051260; GO:1900745; GO:1904047 48535 XM_029334644.2 350 256 389 277 496 Q5SPB1 6.82e-22 Sodium-coupled neutral amino acid symporter 2 (Amino acid transporter A2) (Solute carrier family 38 member 2) (System A amino acid transporter 2) (System A transporter 1) (System N amino acid transporter 2) Danio rerio (Zebrafish) (Brachydanio rerio) alanine transport [GO:0032328]; amino acid import [GO:0043090]; amino acid transmembrane transport [GO:0003333]; amino acid transport [GO:0006865]; glutamine transport [GO:0006868]; L-glutamine import across plasma membrane [GO:1903803]; L-proline import across plasma membrane [GO:1904271]; L-serine import across plasma membrane [GO:1903812]; neutral amino acid transport [GO:0015804]; proline transport [GO:0015824]; regulation of glutamate secretion, neurotransmission [GO:1903294] GO:0003333; GO:0005283; GO:0005295; GO:0005298; GO:0005886; GO:0006865; GO:0006868; GO:0015171; GO:0015172; GO:0015175; GO:0015179; GO:0015186; GO:0015655; GO:0015804; GO:0015824; GO:0032328; GO:0043090; GO:1903294; GO:1903803; GO:1903812; GO:1904271 48536 XM_029332491.2 1433 980 867 1138 1047 P11533 9.42e-31 Dystrophin Gallus gallus (Chicken) actin filament bundle assembly [GO:0051017]; actin filament network formation [GO:0051639] GO:0005737; GO:0005884; GO:0008270; GO:0032432; GO:0042383; GO:0045211; GO:0051015; GO:0051017; GO:0051639; GO:0120025 48537 XM_044309232.1 22 23 28 9 179 NA NA NA NA NA NA 48538 XM_029340601.2 723 325 300 450 677 NA NA NA NA NA NA 48539 XM_044328806.1 2 2 0 5 7 NA NA NA NA NA NA 48540 XM_029340320.2 29 17 26 16 61 P17124 3.95e-33 Histamine H2 receptor (H2R) (HH2R) (Gastric receptor I) Canis lupus familiaris (Dog) (Canis familiaris) chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; gastric acid secretion [GO:0001696]; positive regulation of vasoconstriction [GO:0045907] GO:0001696; GO:0004969; GO:0004993; GO:0005886; GO:0007187; GO:0007268; GO:0030425; GO:0030594; GO:0045202; GO:0045907 48541 XM_044310381.1 26 27 8 5 6 NA NA NA NA NA NA 48542 XR_006394597.1 10 4 3 0 41 NA NA NA NA NA NA 48543 XM_044324106.1 39 10 12 35 46 NA NA NA NA NA NA 48544 XM_044307481.1 77 159 68 135 200 NA NA NA NA NA NA 48545 XR_006396654.1 20 33 0 32 0 NA NA NA NA NA NA 48546 XR_003827497.2 76 29 13 40 79 NA NA NA NA NA NA 48547 XM_029346582.2 1406 1459 673 1391 1559 O14678 8.69e-178 Lysosomal cobalamin transporter ABCD4 (EC 7.6.2.8) (ATP-binding cassette sub-family D member 4) (PMP70-related protein) (P70R) (Peroxisomal membrane protein 1-like) (PXMP1-L) (Peroxisomal membrane protein 69) (PMP69) Homo sapiens (Human) cellular response to leukemia inhibitory factor [GO:1990830]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; fatty acid beta-oxidation [GO:0006635]; long-chain fatty acid import into peroxisome [GO:0015910]; peroxisome organization [GO:0007031]; transmembrane transport [GO:0055085]; very long-chain fatty acid catabolic process [GO:0042760] GO:0005324; GO:0005524; GO:0005765; GO:0005777; GO:0005778; GO:0005789; GO:0006635; GO:0007031; GO:0009235; GO:0015420; GO:0015889; GO:0015910; GO:0016020; GO:0016887; GO:0042626; GO:0042760; GO:0042802; GO:0043190; GO:0055085; GO:1990830 48548 XM_044325256.1 6 19 8 14 58 P19491 6.23e-86 Glutamate receptor 2 (GluR-2) (AMPA-selective glutamate receptor 2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (GluA2) Rattus norvegicus (Rat) cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to glycine [GO:1905430]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226] GO:0000149; GO:0001540; GO:0001919; GO:0004970; GO:0004971; GO:0005234; GO:0005783; GO:0005789; GO:0005886; GO:0007268; GO:0008021; GO:0008092; GO:0008328; GO:0009986; GO:0010226; GO:0014069; GO:0015276; GO:0015277; GO:0016020; GO:0019865; GO:0019901; GO:0021987; GO:0030165; GO:0030424; GO:0030425; GO:0030426; GO:0030672; GO:0031623; GO:0032279; GO:0032281; GO:0032590; GO:0032839; GO:0032991; GO:0035235; GO:0035254; GO:0035255; GO:0036477; GO:0038023; GO:0042734; GO:0042802; GO:0043005; GO:0043025; GO:0043195; GO:0043197; GO:0043198; GO:0043204; GO:0044326; GO:0044327; GO:0045184; GO:0045202; GO:0045211; GO:0048787; GO:0050806; GO:0051117; GO:0051262; GO:0051966; GO:0060992; GO:0097060; GO:0097110; GO:0098685; GO:0098793; GO:0098839; GO:0098978; GO:0099507; GO:0099544; GO:0106033; GO:1904315; GO:1905430; GO:1990416 48549 XM_029330607.2 115 80 49 61 252 O73853 1.41e-85 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Ictalurus punctatus (Channel catfish) (Silurus punctatus) steroid biosynthetic process [GO:0006694] GO:0004508; GO:0005506; GO:0006694; GO:0016020; GO:0020037; GO:0047442 48550 XM_044315981.1 104 27 70 208 136 Q96RS0 4.15e-96 Trimethylguanosine synthase (EC 2.1.1.-) (CLL-associated antigen KW-2) (Cap-specific guanine-N2 methyltransferase) (Hepatocellular carcinoma-associated antigen 137) (Nuclear receptor coactivator 6-interacting protein) (PRIP-interacting protein with methyltransferase motif) (PIMT) (PIPMT) Homo sapiens (Human) 7-methylguanosine cap hypermethylation [GO:0036261]; 7-methylguanosine RNA capping [GO:0009452]; ribonucleoprotein complex biogenesis [GO:0022613]; spliceosomal snRNP assembly [GO:0000387] GO:0000387; GO:0005615; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0008173; GO:0009452; GO:0015030; GO:0022613; GO:0030532; GO:0036261; GO:0071164 48551 XM_029353114.2 105 80 89 134 85 A0A0P0XM10 9.24e-105 Polyamine oxidase 6 (OsPAO6) (EC 1.5.3.-) (Polyamine oxidase B) Oryza sativa subsp. japonica (Rice) spermine catabolic process [GO:0046208] GO:0016491; GO:0016647; GO:0046208; GO:0048046; GO:0050660 48552 XM_044327937.1 168 227 114 984 1638 NA NA NA NA NA NA 48553 XM_044329178.1 112 56 43 145 189 NA NA NA NA NA NA 48554 XM_029340574.2 202 329 111 209 350 NA NA NA NA NA NA 48555 XR_006394061.1 0 0 0 6 0 NA NA NA NA NA NA 48556 XM_044306741.1 13 0 11 30 58 NA NA NA NA NA NA 48557 XM_044325922.1 55 87 166 166 103 A2RUV0 9.6e-148 Neurogenic locus notch homolog protein 1 (Notch 1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; cilium assembly [GO:0060271]; Notch signaling involved in heart development [GO:0061314]; regulation of developmental process [GO:0050793]; regulation of DNA-templated transcription [GO:0006355] GO:0001525; GO:0005509; GO:0005634; GO:0005886; GO:0006355; GO:0030154; GO:0038023; GO:0050793; GO:0060271; GO:0061314 48558 XM_044325922.1 55 87 166 166 103 A2RUV0 8.24e-141 Neurogenic locus notch homolog protein 1 (Notch 1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; cilium assembly [GO:0060271]; Notch signaling involved in heart development [GO:0061314]; regulation of developmental process [GO:0050793]; regulation of DNA-templated transcription [GO:0006355] GO:0001525; GO:0005509; GO:0005634; GO:0005886; GO:0006355; GO:0030154; GO:0038023; GO:0050793; GO:0060271; GO:0061314 48559 XM_044325922.1 55 87 166 166 103 A2RUV0 2e-138 Neurogenic locus notch homolog protein 1 (Notch 1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; cilium assembly [GO:0060271]; Notch signaling involved in heart development [GO:0061314]; regulation of developmental process [GO:0050793]; regulation of DNA-templated transcription [GO:0006355] GO:0001525; GO:0005509; GO:0005634; GO:0005886; GO:0006355; GO:0030154; GO:0038023; GO:0050793; GO:0060271; GO:0061314 48560 XM_044325922.1 55 87 166 166 103 A2RUV0 3.63e-137 Neurogenic locus notch homolog protein 1 (Notch 1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; cilium assembly [GO:0060271]; Notch signaling involved in heart development [GO:0061314]; regulation of developmental process [GO:0050793]; regulation of DNA-templated transcription [GO:0006355] GO:0001525; GO:0005509; GO:0005634; GO:0005886; GO:0006355; GO:0030154; GO:0038023; GO:0050793; GO:0060271; GO:0061314 48561 XM_044325922.1 55 87 166 166 103 A2RUV0 8.53e-135 Neurogenic locus notch homolog protein 1 (Notch 1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; cilium assembly [GO:0060271]; Notch signaling involved in heart development [GO:0061314]; regulation of developmental process [GO:0050793]; regulation of DNA-templated transcription [GO:0006355] GO:0001525; GO:0005509; GO:0005634; GO:0005886; GO:0006355; GO:0030154; GO:0038023; GO:0050793; GO:0060271; GO:0061314 48562 XM_044325922.1 55 87 166 166 103 A2RUV0 1.19e-111 Neurogenic locus notch homolog protein 1 (Notch 1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; cilium assembly [GO:0060271]; Notch signaling involved in heart development [GO:0061314]; regulation of developmental process [GO:0050793]; regulation of DNA-templated transcription [GO:0006355] GO:0001525; GO:0005509; GO:0005634; GO:0005886; GO:0006355; GO:0030154; GO:0038023; GO:0050793; GO:0060271; GO:0061314 48563 XM_044325922.1 55 87 166 166 103 A2RUV0 2.09e-90 Neurogenic locus notch homolog protein 1 (Notch 1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; cilium assembly [GO:0060271]; Notch signaling involved in heart development [GO:0061314]; regulation of developmental process [GO:0050793]; regulation of DNA-templated transcription [GO:0006355] GO:0001525; GO:0005509; GO:0005634; GO:0005886; GO:0006355; GO:0030154; GO:0038023; GO:0050793; GO:0060271; GO:0061314 48564 XM_044325922.1 55 87 166 166 103 A2RUV0 8.99e-86 Neurogenic locus notch homolog protein 1 (Notch 1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; cilium assembly [GO:0060271]; Notch signaling involved in heart development [GO:0061314]; regulation of developmental process [GO:0050793]; regulation of DNA-templated transcription [GO:0006355] GO:0001525; GO:0005509; GO:0005634; GO:0005886; GO:0006355; GO:0030154; GO:0038023; GO:0050793; GO:0060271; GO:0061314 48565 XM_044311916.1 83 55 11 25 37 Q09811 1.38e-26 ATP-dependent DNA helicase hus2/rqh1 (EC 3.6.4.12) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) cellular response to DNA damage stimulus [GO:0006974]; DNA double-strand break processing [GO:0000729]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724]; maintenance of rDNA [GO:0043007]; mitotic intra-S DNA damage checkpoint signaling [GO:0031573]; mitotic recombination-dependent replication fork processing [GO:1990426]; postreplication repair [GO:0006301]; recombinational repair [GO:0000725]; regulation of mitotic recombination-dependent replication fork processing [GO:1903221]; replication fork processing [GO:0031297]; resolution of mitotic recombination intermediates [GO:0071140]; UV-damage excision repair [GO:0070914] GO:0000228; GO:0000724; GO:0000725; GO:0000729; GO:0003677; GO:0005524; GO:0005634; GO:0005694; GO:0005730; GO:0005737; GO:0006268; GO:0006281; GO:0006301; GO:0006310; GO:0006974; GO:0009378; GO:0016887; GO:0031297; GO:0031422; GO:0031573; GO:0032508; GO:0035861; GO:0043007; GO:0043138; GO:0043596; GO:0070914; GO:0071140; GO:1903221; GO:1990426 48566 XM_044316397.1 25 8 10 36 18 NA NA NA NA NA NA 48567 XM_044327927.1 5 10 51 73 52 Q0IQU1 4.33e-43 Laccase-22 (EC 1.10.3.2) (Benzenediol:oxygen oxidoreductase 22) (Diphenol oxidase 22) (Urishiol oxidase 22) Oryza sativa subsp. japonica (Rice) lignin catabolic process [GO:0046274] GO:0005507; GO:0016491; GO:0046274; GO:0048046; GO:0052716 48568 XM_044324533.1 49 4 110 70 129 NA NA NA NA NA NA 48569 XM_044326522.1 16396 39571 25304 37774 9059 Q2TBX5 1.5e-37 Translocon-associated protein subunit delta (TRAP-delta) (Signal sequence receptor subunit delta) (SSR-delta) Bos taurus (Bovine) NA GO:0005789; GO:0012505 48570 XM_029324701.2 163 201 97 63 168 Q96DM1 5.17e-27 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 48571 XM_029324701.2 163 201 97 63 168 Q96DM1 5.17e-27 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 48572 XM_029342205.2 207 130 0 170 235 Q5F450 0 PAN2-PAN3 deadenylation complex catalytic subunit PAN2 (EC 3.1.13.4) (Inactive ubiquitin carboxyl-terminal hydrolase 52) (PAB1P-dependent poly(A)-specific ribonuclease) (Poly(A)-nuclease deadenylation complex subunit 2) (PAN deadenylation complex subunit 2) Gallus gallus (Chicken) mRNA processing [GO:0006397]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; positive regulation of cytoplasmic mRNA processing body assembly [GO:0010606] GO:0000175; GO:0000289; GO:0000932; GO:0003676; GO:0004535; GO:0005634; GO:0006397; GO:0010606; GO:0031251; GO:0046872 48573 XM_044317922.1 2112 1667 932 1841 1530 O97490 3.91e-60 Melanotransferrin (Membrane-bound transferrin-like protein p97) (CD antigen CD228) Oryctolagus cuniculus (Rabbit) ion transport [GO:0006811]; iron ion homeostasis [GO:0055072] GO:0005615; GO:0005886; GO:0006811; GO:0046872; GO:0055072 48574 XM_044317922.1 2112 1667 932 1841 1530 O97490 1.31e-58 Melanotransferrin (Membrane-bound transferrin-like protein p97) (CD antigen CD228) Oryctolagus cuniculus (Rabbit) ion transport [GO:0006811]; iron ion homeostasis [GO:0055072] GO:0005615; GO:0005886; GO:0006811; GO:0046872; GO:0055072 48575 XM_044307345.1 3 9 3 14 7 NA NA NA NA NA NA 48576 XM_044321099.1 17 236 290 342 196 Q91Y77 4.38e-39 Monocarboxylate transporter 10 (MCT 10) (Aromatic amino acid transporter 1) (Solute carrier family 16 member 10) (T-type amino acid transporter 1) Rattus norvegicus (Rat) aromatic amino acid transport [GO:0015801]; thyroid hormone generation [GO:0006590]; thyroid hormone transport [GO:0070327]; thyroid-stimulating hormone secretion [GO:0070460] GO:0005302; GO:0005886; GO:0006590; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0070327; GO:0070460 48577 XM_044318250.1 269 338 343 386 467 P07314 8.46e-135 Glutathione hydrolase 1 proenzyme (EC 3.4.19.13) (Gamma-glutamyltransferase 1) (Gamma-glutamyltranspeptidase 1) (GGT 1) (EC 2.3.2.2) (Leukotriene-C4 hydrolase) (EC 3.4.19.14) (CD antigen CD224) [Cleaved into: Glutathione hydrolase 1 heavy chain; Glutathione hydrolase 1 light chain] Rattus norvegicus (Rat) aging [GO:0007568]; amino acid metabolic process [GO:0006520]; cellular response to oxidative stress [GO:0034599]; cysteine biosynthetic process [GO:0019344]; fatty acid metabolic process [GO:0006631]; glutamate metabolic process [GO:0006536]; glutathione biosynthetic process [GO:0006750]; glutathione catabolic process [GO:0006751]; hepatoblast differentiation [GO:0061017]; hepatocyte differentiation [GO:0070365]; leukotriene D4 biosynthetic process [GO:1901750]; leukotriene metabolic process [GO:0006691]; liver regeneration [GO:0097421]; peptide modification [GO:0031179]; proteolysis [GO:0006508]; regulation of immune system process [GO:0002682]; regulation of inflammatory response [GO:0050727]; response to alcohol [GO:0097305]; response to estradiol [GO:0032355]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]; spermatogenesis [GO:0007283]; zymogen activation [GO:0031638] GO:0000048; GO:0002682; GO:0002951; GO:0005615; GO:0005886; GO:0006508; GO:0006520; GO:0006536; GO:0006631; GO:0006691; GO:0006750; GO:0006751; GO:0007283; GO:0007568; GO:0016755; GO:0019344; GO:0031179; GO:0031638; GO:0031982; GO:0032355; GO:0032496; GO:0034599; GO:0034612; GO:0036374; GO:0050727; GO:0061017; GO:0070365; GO:0097305; GO:0097421; GO:0102953; GO:0103068; GO:1901750 48578 XM_044326637.1 0 7 0 8 0 Q6DUZ9 8.56e-27 EARP-interacting protein homolog Gekko japonicus (Schlegel's Japanese gecko) NA NA 48579 XM_044315065.1 5 14 5 35 0 Q96AY4 1.53e-106 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 48580 XM_044315065.1 5 14 5 35 0 Q96AY4 2.41e-100 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 48581 XM_044315065.1 5 14 5 35 0 Q96AY4 5.04e-99 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 48582 XM_044315065.1 5 14 5 35 0 Q96AY4 3.31e-98 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 48583 XM_044315065.1 5 14 5 35 0 Q96AY4 2.38e-96 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 48584 XM_044315065.1 5 14 5 35 0 Q96AY4 1.59e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 48585 XM_044325002.1 38 9 84 50 65 Q99315 3.4e-85 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 48586 XM_029343369.2 18 28 0 30 12 NA NA NA NA NA NA 48587 XM_044308874.1 0 0 3 69 28 NA NA NA NA NA NA 48588 XR_003824503.2 8 1 3 0 30 NA NA NA NA NA NA 48589 XM_029328457.2 2448 1926 1182 2459 1811 Q9U5L1 4.5e-160 Signal recognition particle receptor subunit alpha homolog (DP-alpha) (Docking protein alpha) (SR-alpha) (GTP-binding protein) Drosophila melanogaster (Fruit fly) axonogenesis [GO:0007409]; protein targeting [GO:0006605]; protein targeting to ER [GO:0045047]; regulation of protein secretion [GO:0050708]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614] GO:0003723; GO:0003924; GO:0005047; GO:0005525; GO:0005785; GO:0005789; GO:0006605; GO:0006614; GO:0007409; GO:0012505; GO:0016020; GO:0045047; GO:0050708 48590 XM_029328457.2 2448 1926 1182 2459 1811 Q9U5L1 7.97e-29 Signal recognition particle receptor subunit alpha homolog (DP-alpha) (Docking protein alpha) (SR-alpha) (GTP-binding protein) Drosophila melanogaster (Fruit fly) axonogenesis [GO:0007409]; protein targeting [GO:0006605]; protein targeting to ER [GO:0045047]; regulation of protein secretion [GO:0050708]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614] GO:0003723; GO:0003924; GO:0005047; GO:0005525; GO:0005785; GO:0005789; GO:0006605; GO:0006614; GO:0007409; GO:0012505; GO:0016020; GO:0045047; GO:0050708 48591 XM_029334994.2 5197 4615 2926 4649 4096 A6QLR4 1.96e-27 Flotillin-2 Bos taurus (Bovine) cell adhesion [GO:0007155]; protein localization to plasma membrane [GO:0072659]; regulation of myoblast differentiation [GO:0045661] GO:0005768; GO:0005886; GO:0007155; GO:0016600; GO:0030139; GO:0031410; GO:0045661; GO:0072659 48592 XM_044324215.1 0 0 0 129 0 P50904 0 Ras GTPase-activating protein 1 (GAP) (GTPase-activating protein) (RasGAP) (Ras p21 protein activator) (p120GAP) Rattus norvegicus (Rat) actin cytoskeleton organization [GO:0030036]; activation of GTPase activity [GO:0090630]; blood vessel morphogenesis [GO:0048514]; cell adhesion [GO:0007155]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; male genitalia development [GO:0030539]; mitotic cytokinesis [GO:0000281]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of glucose import [GO:0046326]; positive regulation of GTPase activity [GO:0043547]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; regulation of actin filament polymerization [GO:0030833]; response to insulin [GO:0032868]; response to xenobiotic stimulus [GO:0009410]; signal transduction [GO:0007165]; vasculogenesis [GO:0001570] GO:0000281; GO:0001570; GO:0001726; GO:0001784; GO:0001934; GO:0001953; GO:0005096; GO:0005102; GO:0005161; GO:0005829; GO:0005886; GO:0007155; GO:0007162; GO:0007165; GO:0009410; GO:0016020; GO:0030036; GO:0030539; GO:0030833; GO:0030971; GO:0031965; GO:0032868; GO:0036120; GO:0043066; GO:0043422; GO:0043524; GO:0043547; GO:0044325; GO:0044344; GO:0044877; GO:0046326; GO:0048146; GO:0048514; GO:0050731; GO:0051020; GO:0071364; GO:0090630; GO:1990782 48593 XM_029350246.2 0 168 0 0 51 NA NA NA NA NA NA 48594 XM_029358058.2 18 0 0 1 8 NA NA NA NA NA NA 48595 XM_029329983.2 1085 1482 811 870 793 Q86YS6 2.04e-77 Ras-related protein Rab-43 (Ras-related protein Rab-41) Homo sapiens (Human) autophagosome assembly [GO:0000045]; cellular response to type II interferon [GO:0071346]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886]; phagosome maturation [GO:0090382]; retrograde transport, plasma membrane to Golgi [GO:0035526]; toxin transport [GO:1901998]; virion assembly [GO:0019068] GO:0000045; GO:0003924; GO:0005525; GO:0005794; GO:0006886; GO:0007030; GO:0012505; GO:0019068; GO:0030670; GO:0032588; GO:0035526; GO:0045335; GO:0070062; GO:0071346; GO:0090382; GO:1901998 48596 XM_044307772.1 0 56 0 0 0 P79385 1.13e-22 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (SED1) (Sperm surface protein SP47) (PP47) Sus scrofa (Pig) angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; single fertilization [GO:0007338] GO:0001525; GO:0002080; GO:0005576; GO:0007155; GO:0007338 48597 XM_029355945.2 661 607 471 653 402 Q9CPW7 1.65e-50 Zinc finger matrin-type protein 2 Mus musculus (Mouse) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0003677; GO:0005634; GO:0008270; GO:0046540; GO:0071005 48598 XM_029335955.2 960 1167 876 1026 588 Q29S14 3.59e-74 Golgi apparatus membrane protein TVP23 homolog B Bos taurus (Bovine) protein secretion [GO:0009306]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0009306; GO:0016192 48599 XM_044324438.1 1132 2242 1437 575 1721 NA NA NA NA NA NA 48600 XM_029351885.2 162 152 114 122 142 NA NA NA NA NA NA 48601 XR_003827801.2 5 0 1 10 5 NA NA NA NA NA NA 48602 XM_044308421.1 114 275 36 47 8 Q54PI5 2.94e-39 Probable gluconokinase (EC 2.7.1.12) (Gluconate kinase) Dictyostelium discoideum (Social amoeba) D-gluconate catabolic process [GO:0046177]; phosphorylation [GO:0016310] GO:0005524; GO:0016310; GO:0046177; GO:0046316 48603 XM_029334082.2 0 0 35 82 0 Q09081 1.33e-142 Potassium voltage-gated channel subfamily A member 2 (KC22) (Voltage-gated potassium channel subunit Kv1.2) Oryctolagus cuniculus (Rabbit) neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233] GO:0005249; GO:0005251; GO:0005789; GO:0005886; GO:0008076; GO:0014059; GO:0019228; GO:0019233; GO:0021633; GO:0030027; GO:0030424; GO:0030425; GO:0031258; GO:0032809; GO:0033010; GO:0034765; GO:0042734; GO:0043194; GO:0043204; GO:0043679; GO:0044224; GO:0045188; GO:0051260; GO:0071805 48604 XM_029338155.2 4539 6841 5119 22515 15575 NA NA NA NA NA NA 48605 XM_044315082.1 0 15 0 0 0 NA NA NA NA NA NA 48606 XM_044311348.1 142 81 166 51 580 P14381 1.17e-25 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 48607 XM_044311348.1 142 81 166 51 580 P14381 1.17e-25 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 48608 XM_044311348.1 142 81 166 51 580 P14381 1.17e-25 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 48609 XR_006394496.1 42 49 19 36 57 NA NA NA NA NA NA 48610 XR_003825081.2 58 48 53 24 135 NA NA NA NA NA NA 48611 XR_006393894.1 41 2 25 5 151 NA NA NA NA NA NA 48612 XM_044327747.1 283 191 161 35 195 Q05609 5.77e-24 Serine/threonine-protein kinase CTR1 (EC 2.7.11.1) (Protein CONSTITUTIVE TRIPLE RESPONSE1) Arabidopsis thaliana (Mouse-ear cress) ethylene-activated signaling pathway [GO:0009873]; gibberellin biosynthetic process [GO:0009686]; negative regulation of ethylene-activated signaling pathway [GO:0010105]; protein autophosphorylation [GO:0046777]; regulation of post-embryonic root development [GO:2000069]; regulation of stem cell division [GO:2000035]; regulation of timing of transition from vegetative to reproductive phase [GO:0048510]; response to ethylene [GO:0009723]; response to fructose [GO:0009750]; response to hypoxia [GO:0001666]; response to sucrose [GO:0009744]; sugar mediated signaling pathway [GO:0010182] GO:0001666; GO:0004674; GO:0004712; GO:0005524; GO:0005789; GO:0009686; GO:0009723; GO:0009744; GO:0009750; GO:0009873; GO:0010105; GO:0010182; GO:0046777; GO:0048510; GO:0106310; GO:2000035; GO:2000069 48613 XM_029348449.2 365 253 168 375 334 Q9NXS3 3.62e-39 Kelch-like protein 28 (BTB/POZ domain-containing protein 5) Homo sapiens (Human) NA NA 48614 XM_044313813.1 43 11 33 23 37 P07949 5.19e-73 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; axon guidance [GO:0007411]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; lymphocyte migration into lymphoid organs [GO:0097021]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; posterior midgut development [GO:0007497]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006468; GO:0006919; GO:0007156; GO:0007158; GO:0007165; GO:0007169; GO:0007411; GO:0007497; GO:0009410; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0038023; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0097021; GO:0098797; GO:2001241 48615 XM_044309661.1 378 565 311 350 71 Q3SZZ5 3.2e-41 Transmembrane protein 208 Bos taurus (Bovine) autophagy [GO:0006914]; vacuolar protein processing [GO:0006624] GO:0005773; GO:0005789; GO:0006624; GO:0006914 48616 XM_029358736.2 46 0 83 0 8 Q80UJ7 0 Rab3 GTPase-activating protein catalytic subunit (RAB3 GTPase-activating protein 130 kDa subunit) (Rab3-GAP p130) (Rab3-GAP) Mus musculus (Mouse) brain development [GO:0007420]; camera-type eye development [GO:0043010]; establishment of protein localization to endoplasmic reticulum membrane [GO:0097051]; excitatory postsynaptic potential [GO:0060079]; face morphogenesis [GO:0060325]; hypothalamus development [GO:0021854]; lipid droplet organization [GO:0034389]; positive regulation of autophagosome assembly [GO:2000786]; positive regulation of endoplasmic reticulum tubular network organization [GO:1903373]; positive regulation of gene expression [GO:0010628]; positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization [GO:0061646]; positive regulation of GTPase activity [GO:0043547]; positive regulation of protein lipidation [GO:1903061]; protein stabilization [GO:0050821]; regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903233]; regulation of GTPase activity [GO:0043087]; regulation of Rab protein signal transduction [GO:0032483]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic vesicle priming [GO:0010807]; synaptic vesicle transport [GO:0048489] GO:0005085; GO:0005096; GO:0005737; GO:0005794; GO:0005811; GO:0007420; GO:0010628; GO:0010807; GO:0021854; GO:0031267; GO:0032483; GO:0032991; GO:0034389; GO:0043010; GO:0043087; GO:0043547; GO:0048172; GO:0048489; GO:0050821; GO:0060076; GO:0060079; GO:0060325; GO:0061646; GO:0071782; GO:0097051; GO:0098794; GO:1903061; GO:1903233; GO:1903373; GO:2000786 48617 XM_029358736.2 46 0 83 0 8 Q80UJ7 1.16e-21 Rab3 GTPase-activating protein catalytic subunit (RAB3 GTPase-activating protein 130 kDa subunit) (Rab3-GAP p130) (Rab3-GAP) Mus musculus (Mouse) brain development [GO:0007420]; camera-type eye development [GO:0043010]; establishment of protein localization to endoplasmic reticulum membrane [GO:0097051]; excitatory postsynaptic potential [GO:0060079]; face morphogenesis [GO:0060325]; hypothalamus development [GO:0021854]; lipid droplet organization [GO:0034389]; positive regulation of autophagosome assembly [GO:2000786]; positive regulation of endoplasmic reticulum tubular network organization [GO:1903373]; positive regulation of gene expression [GO:0010628]; positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization [GO:0061646]; positive regulation of GTPase activity [GO:0043547]; positive regulation of protein lipidation [GO:1903061]; protein stabilization [GO:0050821]; regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903233]; regulation of GTPase activity [GO:0043087]; regulation of Rab protein signal transduction [GO:0032483]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic vesicle priming [GO:0010807]; synaptic vesicle transport [GO:0048489] GO:0005085; GO:0005096; GO:0005737; GO:0005794; GO:0005811; GO:0007420; GO:0010628; GO:0010807; GO:0021854; GO:0031267; GO:0032483; GO:0032991; GO:0034389; GO:0043010; GO:0043087; GO:0043547; GO:0048172; GO:0048489; GO:0050821; GO:0060076; GO:0060079; GO:0060325; GO:0061646; GO:0071782; GO:0097051; GO:0098794; GO:1903061; GO:1903233; GO:1903373; GO:2000786 48618 XR_006392925.1 41 2 25 5 151 NA NA NA NA NA NA 48619 XM_029336295.2 5251 3846 2978 5385 4656 Q03168 8.65e-175 Lysosomal aspartic protease (EC 3.4.23.-) Aedes aegypti (Yellowfever mosquito) (Culex aegypti) proteolysis [GO:0006508] GO:0004190; GO:0005764; GO:0006508 48620 XR_006397285.1 0 0 0 12 4 NA NA NA NA NA NA 48621 XM_044310344.1 13 2 17 70 38 NA NA NA NA NA NA 48622 XM_044328499.1 1193 694 658 2040 1105 Q9BYK8 2.11e-168 Helicase with zinc finger domain 2 (ATP-dependent helicase PRIC285) (Helicase with zinc finger 2, transcriptional coactivator) (PPAR-alpha-interacting complex protein 285) (PPAR-gamma DNA-binding domain-interacting protein 1) (PDIP1) (PPAR-gamma DBD-interacting protein 1) (Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein) (EC 3.6.4.-) Homo sapiens (Human) nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000184; GO:0003677; GO:0003723; GO:0003724; GO:0004540; GO:0005524; GO:0005654; GO:0005737; GO:0016020; GO:0030374; GO:0045944; GO:0046872 48623 XM_044328499.1 1193 694 658 2040 1105 Q9BYK8 1.78e-95 Helicase with zinc finger domain 2 (ATP-dependent helicase PRIC285) (Helicase with zinc finger 2, transcriptional coactivator) (PPAR-alpha-interacting complex protein 285) (PPAR-gamma DNA-binding domain-interacting protein 1) (PDIP1) (PPAR-gamma DBD-interacting protein 1) (Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein) (EC 3.6.4.-) Homo sapiens (Human) nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000184; GO:0003677; GO:0003723; GO:0003724; GO:0004540; GO:0005524; GO:0005654; GO:0005737; GO:0016020; GO:0030374; GO:0045944; GO:0046872 48624 XM_044328499.1 1193 694 658 2040 1105 Q9BYK8 6.66e-29 Helicase with zinc finger domain 2 (ATP-dependent helicase PRIC285) (Helicase with zinc finger 2, transcriptional coactivator) (PPAR-alpha-interacting complex protein 285) (PPAR-gamma DNA-binding domain-interacting protein 1) (PDIP1) (PPAR-gamma DBD-interacting protein 1) (Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein) (EC 3.6.4.-) Homo sapiens (Human) nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000184; GO:0003677; GO:0003723; GO:0003724; GO:0004540; GO:0005524; GO:0005654; GO:0005737; GO:0016020; GO:0030374; GO:0045944; GO:0046872 48625 XM_029358138.2 476 184 139 336 289 P29146 0 PC3-like endoprotease variant A (EC 3.4.21.-) (SPC3) Hydra vulgaris (Hydra) (Hydra attenuata) proteolysis [GO:0006508] GO:0004252; GO:0006508 48626 XM_029331382.2 6 0 12 43 23 P38661 9.32e-49 Probable protein disulfide-isomerase A6 (EC 5.3.4.1) (P5) Medicago sativa (Alfalfa) NA GO:0003756; GO:0005788 48627 XM_044328674.1 134 0 0 0 81 Q8STF0 2.26e-34 Calmodulin (CaM) Strongylocentrotus intermedius (Sea urchin) NA GO:0005509 48628 XM_029348651.2 180 269 62 110 165 NA NA NA NA NA NA 48629 XM_044318448.1 531 294 556 517 814 Q12872 8.26e-22 Splicing factor, suppressor of white-apricot homolog (Splicing factor, arginine/serine-rich 8) (Suppressor of white apricot protein homolog) Homo sapiens (Human) alternative mRNA splicing, via spliceosome [GO:0000380]; mRNA 5'-splice site recognition [GO:0000395]; negative regulation of mRNA splicing, via spliceosome [GO:0048025] GO:0000380; GO:0000395; GO:0003723; GO:0005634; GO:0048025 48630 XM_044327070.1 5 9 5 3 38 P48052 4.97e-70 Carboxypeptidase A2 (EC 3.4.17.15) Homo sapiens (Human) protein catabolic process in the vacuole [GO:0007039]; proteolysis [GO:0006508] GO:0004180; GO:0004181; GO:0005576; GO:0005615; GO:0005773; GO:0006508; GO:0007039; GO:0008270 48631 XM_029329396.2 131 44 64 150 108 P52569 1.72e-146 Cationic amino acid transporter 2 (CAT-2) (CAT2) (Low affinity cationic amino acid transporter 2) (Solute carrier family 7 member 2) Homo sapiens (Human) amino acid import across plasma membrane [GO:0089718]; amino acid transport [GO:0006865]; L-alpha-amino acid transmembrane transport [GO:1902475]; L-amino acid transport [GO:0015807]; L-arginine import across plasma membrane [GO:0097638]; L-arginine transmembrane transport [GO:1903826]; L-ornithine transmembrane transport [GO:1903352]; transport across blood-brain barrier [GO:0150104] GO:0000064; GO:0005886; GO:0006865; GO:0015171; GO:0015174; GO:0015179; GO:0015189; GO:0015807; GO:0030054; GO:0061459; GO:0089718; GO:0097638; GO:0150104; GO:1902475; GO:1903352; GO:1903826 48632 XR_003824254.2 0 13 0 0 0 NA NA NA NA NA NA 48633 XM_029351401.2 79 0 75 112 0 P34410 3.08e-25 TWiK family of potassium channels protein 7 Caenorhabditis elegans potassium ion transmembrane transport [GO:0071805]; stabilization of membrane potential [GO:0030322] GO:0005886; GO:0015271; GO:0022841; GO:0030322; GO:0071805 48634 XM_044317460.1 5 26 0 26 27 O62852 7.61e-52 Short transient receptor potential channel 5 (Rtrp5) (TrpC5) (Capacitative calcium entry channel 2) (CCE2) Oryctolagus cuniculus (Rabbit) neuron apoptotic process [GO:0051402]; phosphatidylserine exposure on apoptotic cell surface [GO:0070782] GO:0005262; GO:0005886; GO:0034704; GO:0051402; GO:0070679; GO:0070782 48635 XM_044310942.1 37 72 8 3 47 NA NA NA NA NA NA 48636 XM_044307639.1 14 0 26 0 35 P98092 7.4e-27 Hemocytin (Humoral lectin) Bombyx mori (Silk moth) cell adhesion [GO:0007155] GO:0007155; GO:0030246 48637 XM_029348172.2 1302 1434 562 942 1162 A2BDB7 3.26e-21 Probable RNA polymerase II nuclear localization protein SLC7A6OS (Solute carrier family 7 member 6 opposite strand transcript homolog) Xenopus laevis (African clawed frog) protein transport [GO:0015031] GO:0005634; GO:0005737; GO:0015031 48638 XR_006391308.1 25 15 20 34 62 NA NA NA NA NA NA 48639 XM_029343006.2 86 0 27 0 98 O88874 1.82e-98 Cyclin-K Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; in utero embryonic development [GO:0001701]; negative regulation by host of viral genome replication [GO:0044828]; negative regulation of stem cell differentiation [GO:2000737]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues [GO:2001165]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; regulation of signal transduction [GO:0009966]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366] GO:0001701; GO:0002944; GO:0002945; GO:0004693; GO:0005634; GO:0005654; GO:0006357; GO:0006366; GO:0006974; GO:0007049; GO:0008024; GO:0008353; GO:0009966; GO:0016538; GO:0019901; GO:0032786; GO:0032968; GO:0044828; GO:0051301; GO:0061575; GO:0070816; GO:2000737; GO:2001165 48640 XM_029338072.2 173 176 94 200 180 NA NA NA NA NA NA 48641 XM_029338978.2 9819 12128 9334 10450 6966 P45478 3.54e-132 Palmitoyl-protein thioesterase 1 (PPT-1) (EC 3.1.2.22) (Palmitoyl-protein hydrolase 1) Bos taurus (Bovine) brain development [GO:0007420]; lipid catabolic process [GO:0016042]; lysosomal lumen acidification [GO:0007042]; membrane raft organization [GO:0031579]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of neuron apoptotic process [GO:0043524]; nervous system development [GO:0007399]; pinocytosis [GO:0006907]; positive regulation of pinocytosis [GO:0048549]; positive regulation of receptor-mediated endocytosis [GO:0048260]; protein depalmitoylation [GO:0002084]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0002084; GO:0005576; GO:0005634; GO:0005764; GO:0005794; GO:0005829; GO:0006898; GO:0006907; GO:0007042; GO:0007399; GO:0007420; GO:0008021; GO:0008474; GO:0015031; GO:0016042; GO:0016290; GO:0016790; GO:0030308; GO:0030424; GO:0031579; GO:0043066; GO:0043231; GO:0043524; GO:0045121; GO:0048260; GO:0048549; GO:0120146 48642 XR_003828203.2 31 20 20 10 34 NA NA NA NA NA NA 48643 XM_044317141.1 29 288 0 0 0 NA NA NA NA NA NA 48644 XM_044316743.1 53 10 45 39 98 NA NA NA NA NA NA 48645 XM_029351861.2 379 131 221 139 220 Q8CC12 4.43e-114 Codanin-1 Mus musculus (Mouse) chromatin organization [GO:0006325]; import into nucleus [GO:0051170]; nuclear envelope organization [GO:0006998]; protein localization [GO:0008104] GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0006325; GO:0006998; GO:0008104; GO:0012505; GO:0051170 48646 XR_006393470.1 29 0 4 0 27 NA NA NA NA NA NA 48647 XM_029341588.2 66 51 0 0 0 A2AJN7 2.98e-177 Solute carrier family 4 member 11 (Sodium borate cotransporter 1) (NaBC1) Mus musculus (Mouse) bicarbonate transport [GO:0015701]; borate transport [GO:0046713]; cellular cation homeostasis [GO:0030003]; cellular hypotonic response [GO:0071476]; cellular response to oxidative stress [GO:0034599]; fluid transport [GO:0042044]; ion homeostasis [GO:0050801]; proton transmembrane transport [GO:1902600]; regulation of mesenchymal stem cell differentiation [GO:2000739]; regulation of mitochondrial membrane potential [GO:0051881]; sodium ion transport [GO:0006814]; transmembrane transport [GO:0055085] GO:0005272; GO:0005372; GO:0005452; GO:0005886; GO:0006814; GO:0012506; GO:0015078; GO:0015106; GO:0015252; GO:0015293; GO:0015701; GO:0016323; GO:0016324; GO:0022857; GO:0030003; GO:0034599; GO:0042044; GO:0046713; GO:0046715; GO:0046983; GO:0050801; GO:0051881; GO:0055085; GO:0071476; GO:1902600; GO:2000739 48648 XR_006391911.1 0 0 2 0 6 NA NA NA NA NA NA 48649 XM_029336443.2 129 55 119 140 191 NA NA NA NA NA NA 48650 XR_006397998.1 282 59 128 102 231 NA NA NA NA NA NA 48651 XM_044326860.1 39 22 5 30 39 NA NA NA NA NA NA 48652 XM_044319968.1 56 326 90 671 92 NA NA NA NA NA NA 48653 XM_029357810.2 14 10 8 10 146 NA NA NA NA NA NA 48654 XM_029345585.2 145 88 206 184 406 A5PLK6 2.29e-35 Regulator of G-protein signaling protein-like Homo sapiens (Human) NA GO:0016020 48655 XM_044320095.1 29 7 10 3 1 NA NA NA NA NA NA 48656 XM_029326951.2 24 384 250 32 286 NA NA NA NA NA NA 48657 XM_029341154.2 42 9 9 64 27 Q9H1D0 4.34e-53 Transient receptor potential cation channel subfamily V member 6 (TrpV6) (CaT-like) (CaT-L) (Calcium transport protein 1) (CaT1) (Epithelial calcium channel 2) (ECaC2) Homo sapiens (Human) calcium ion homeostasis [GO:0055074]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; parathyroid hormone secretion [GO:0035898]; regulation of calcium ion-dependent exocytosis [GO:0017158]; response to calcium ion [GO:0051592] GO:0005216; GO:0005262; GO:0005516; GO:0005886; GO:0006816; GO:0017158; GO:0034704; GO:0035898; GO:0042802; GO:0046872; GO:0051592; GO:0055074; GO:0070588; GO:0098703 48658 XM_044318690.1 763 0 0 782 1140 P42695 0 Condensin-2 complex subunit D3 (Non-SMC condensin II complex subunit D3) (hCAP-D3) Homo sapiens (Human) cell division [GO:0051301]; meiotic chromosome condensation [GO:0010032]; mitotic chromosome condensation [GO:0007076]; positive regulation of chromosome condensation [GO:1905821]; positive regulation of chromosome segregation [GO:0051984]; positive regulation of chromosome separation [GO:1905820] GO:0000779; GO:0000794; GO:0000796; GO:0005654; GO:0005721; GO:0007076; GO:0010032; GO:0016020; GO:0035064; GO:0042393; GO:0051301; GO:0051984; GO:1905820; GO:1905821 48659 XM_029338662.2 2590 1986 2002 1659 1935 Q9WV92 2.11e-94 Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1) (Erythrocyte membrane protein band 4.1-like 3) [Cleaved into: Band 4.1-like protein 3, N-terminally processed] Mus musculus (Mouse) actomyosin structure organization [GO:0031032]; apoptotic process [GO:0006915]; axon development [GO:0061564]; cortical actin cytoskeleton organization [GO:0030866]; cortical cytoskeleton organization [GO:0030865]; myelin maintenance [GO:0043217]; neuron projection morphogenesis [GO:0048812]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; protein localization to plasma membrane [GO:0072659]; regulation of cell shape [GO:0008360] GO:0002175; GO:0003779; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0005911; GO:0006915; GO:0008360; GO:0014069; GO:0030054; GO:0030865; GO:0030866; GO:0030913; GO:0031032; GO:0033270; GO:0043217; GO:0044224; GO:0048812; GO:0061564; GO:0071205; GO:0072659; GO:0106006; GO:1990227 48660 XM_029343337.2 608 551 584 861 558 Q9NV56 3.3e-31 MRG/MORF4L-binding protein (MRG-binding protein) (Up-regulated in colon cancer 4) (Urcc4) Homo sapiens (Human) chromatin organization [GO:0006325]; histone acetylation [GO:0016573]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of double-strand break repair [GO:2000779]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000786; GO:0005654; GO:0006325; GO:0006357; GO:0016573; GO:0035267; GO:0042981; GO:0043967; GO:0043968; GO:0045893; GO:0051726; GO:1905168; GO:2000779 48661 XM_029324605.2 0 0 0 4 6 NA NA NA NA NA NA 48662 XM_044309906.1 31 0 105 111 280 NA NA NA NA NA NA 48663 XM_044310784.1 155 43 127 102 319 NA NA NA NA NA NA 48664 XR_006394548.1 0 0 0 0 9 NA NA NA NA NA NA 48665 XM_029354018.2 25 8 33 44 53 NA NA NA NA NA NA 48666 XM_029350277.2 15 20 12 12 92 P29318 2.74e-47 Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) (cEK4) (Tyrosine-protein kinase receptor ETK1) Gallus gallus (Chicken) cell migration [GO:0016477]; ephrin receptor signaling pathway [GO:0048013]; fasciculation of motor neuron axon [GO:0097156]; fasciculation of sensory neuron axon [GO:0097155]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of focal adhesion assembly [GO:0051893]; regulation of GTPase activity [GO:0043087]; regulation of microtubule cytoskeleton organization [GO:0070507] GO:0005003; GO:0005004; GO:0005524; GO:0005769; GO:0005886; GO:0010717; GO:0016477; GO:0032956; GO:0043087; GO:0048013; GO:0051893; GO:0070507; GO:0097155; GO:0097156 48667 XM_029352043.2 676 807 453 881 716 A7SDW5 0 Eukaryotic translation initiation factor 3 subunit L (eIF3l) Nematostella vectensis (Starlet sea anemone) formation of cytoplasmic translation initiation complex [GO:0001732]; translational initiation [GO:0006413] GO:0001732; GO:0003743; GO:0005852; GO:0006413; GO:0016282; GO:0033290 48668 XM_029346816.2 0 0 15 0 1 Q09811 3.55e-51 ATP-dependent DNA helicase hus2/rqh1 (EC 3.6.4.12) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) cellular response to DNA damage stimulus [GO:0006974]; DNA double-strand break processing [GO:0000729]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724]; maintenance of rDNA [GO:0043007]; mitotic intra-S DNA damage checkpoint signaling [GO:0031573]; mitotic recombination-dependent replication fork processing [GO:1990426]; postreplication repair [GO:0006301]; recombinational repair [GO:0000725]; regulation of mitotic recombination-dependent replication fork processing [GO:1903221]; replication fork processing [GO:0031297]; resolution of mitotic recombination intermediates [GO:0071140]; UV-damage excision repair [GO:0070914] GO:0000228; GO:0000724; GO:0000725; GO:0000729; GO:0003677; GO:0005524; GO:0005634; GO:0005694; GO:0005730; GO:0005737; GO:0006268; GO:0006281; GO:0006301; GO:0006310; GO:0006974; GO:0009378; GO:0016887; GO:0031297; GO:0031422; GO:0031573; GO:0032508; GO:0035861; GO:0043007; GO:0043138; GO:0043596; GO:0070914; GO:0071140; GO:1903221; GO:1990426 48669 XM_029335757.2 0 0 0 0 246 O62809 1.4e-33 Orexin receptor type 2 (Ox-2-R) (Ox2-R) (Ox2R) (Hypocretin receptor type 2) Sus scrofa (Pig) circadian sleep/wake cycle process [GO:0022410]; feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; locomotion [GO:0040011]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; regulation of circadian sleep/wake cycle, wakefulness [GO:0010840]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0004930; GO:0005886; GO:0007186; GO:0007200; GO:0007218; GO:0007631; GO:0010840; GO:0016499; GO:0022410; GO:0040011; GO:0051480 48670 XM_029342682.2 273 340 129 367 260 NA NA NA NA NA NA 48671 XR_006397936.1 206 207 128 180 177 NA NA NA NA NA NA 48672 XM_029348370.2 292 458 316 578 445 Q96LT4 3.16e-133 Sphingomyelin synthase-related protein 1 (SMSr) (EC 2.7.8.-) (Ceramide phosphoethanolamine synthase) (CPE synthase) (Sterile alpha motif domain-containing protein 8) (SAM domain-containing protein 8) Homo sapiens (Human) ceramide biosynthetic process [GO:0046513]; ceramide phosphoethanolamine biosynthetic process [GO:1905373]; regulation of ceramide biosynthetic process [GO:2000303]; sphingolipid biosynthetic process [GO:0030148]; sphingomyelin biosynthetic process [GO:0006686] GO:0000139; GO:0002950; GO:0005783; GO:0005789; GO:0005829; GO:0005886; GO:0006686; GO:0016020; GO:0030148; GO:0033188; GO:0046513; GO:0047493; GO:1905373; GO:2000303 48673 XR_006394369.1 0 10 0 1 3 NA NA NA NA NA NA 48674 XR_006393991.1 67 116 32 121 228 O57525 3.01e-60 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Rana dybowskii (Dybovsky's frog) (Korean brown frog) steroid biosynthetic process [GO:0006694] GO:0004508; GO:0005506; GO:0006694; GO:0016020; GO:0020037; GO:0047442 48675 XR_006393991.1 67 116 32 121 228 O57525 3.01e-60 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Rana dybowskii (Dybovsky's frog) (Korean brown frog) steroid biosynthetic process [GO:0006694] GO:0004508; GO:0005506; GO:0006694; GO:0016020; GO:0020037; GO:0047442 48676 XR_006393991.1 67 116 32 121 228 O57525 3.01e-60 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Rana dybowskii (Dybovsky's frog) (Korean brown frog) steroid biosynthetic process [GO:0006694] GO:0004508; GO:0005506; GO:0006694; GO:0016020; GO:0020037; GO:0047442 48677 XR_006393991.1 67 116 32 121 228 O57525 3.01e-60 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Rana dybowskii (Dybovsky's frog) (Korean brown frog) steroid biosynthetic process [GO:0006694] GO:0004508; GO:0005506; GO:0006694; GO:0016020; GO:0020037; GO:0047442 48678 XM_044313167.1 0 22 3 0 30 NA NA NA NA NA NA 48679 XM_044325873.1 35 49 25 0 41 NA NA NA NA NA NA 48680 XM_029330254.2 79 4 125 44 402 Q9NXJ5 1.17e-37 Pyroglutamyl-peptidase 1 (EC 3.4.19.3) (5-oxoprolyl-peptidase) (Pyroglutamyl aminopeptidase I) (PAP-I) (Pyroglutamyl-peptidase I) (PGP-I) (Pyrrolidone-carboxylate peptidase) Homo sapiens (Human) protein catabolic process [GO:0030163]; proteolysis [GO:0006508] GO:0005829; GO:0006508; GO:0016920; GO:0030163 48681 XM_029331243.2 653 0 101 395 286 Q96D71 1.13e-25 RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1) Homo sapiens (Human) endocytosis [GO:0006897]; endosomal transport [GO:0016197] GO:0005509; GO:0005829; GO:0005886; GO:0005905; GO:0006897; GO:0016197; GO:0017124 48682 XM_029343701.2 0 0 0 0 16 NA NA NA NA NA NA 48683 XM_029349446.2 244 156 176 263 599 NA NA NA NA NA NA 48684 XM_044325476.1 30 20 75 4 178 Q80SY4 2.16e-48 E3 ubiquitin-protein ligase MIB1 (EC 2.3.2.27) (DAPK-interacting protein 1) (DIP-1) (Mind bomb homolog 1) (RING-type E3 ubiquitin transferase MIB1) Mus musculus (Mouse) blood vessel development [GO:0001568]; endocytosis [GO:0006897]; heart development [GO:0007507]; heart looping [GO:0001947]; in utero embryonic development [GO:0001701]; negative regulation of neuron differentiation [GO:0045665]; neural tube formation [GO:0001841]; neuron differentiation [GO:0030182]; Notch signaling pathway [GO:0007219]; positive regulation of endocytosis [GO:0045807]; protein ubiquitination [GO:0016567]; somitogenesis [GO:0001756]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0001568; GO:0001701; GO:0001756; GO:0001841; GO:0001947; GO:0004842; GO:0005737; GO:0005813; GO:0005886; GO:0006511; GO:0006897; GO:0007219; GO:0007507; GO:0008270; GO:0014069; GO:0016567; GO:0030182; GO:0031410; GO:0045665; GO:0045807 48685 XM_044319113.1 187 103 60 89 28 NA NA NA NA NA NA 48686 XM_044307634.1 98 322 73 259 526 NA NA NA NA NA NA 48687 XM_044321528.1 160 236 19 468 55 NA NA NA NA NA NA 48688 XR_006396500.1 0 0 0 4 6 NA NA NA NA NA NA 48689 XM_044313367.1 53 18 63 40 244 NA NA NA NA NA NA 48690 XM_029345519.2 1666 3410 1029 1631 1472 Q7ZUB3 2.34e-47 Tetraspanin-31 (Tspan-31) (Sarcoma-amplified sequence homolog) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005886 48691 XM_029341155.2 0 0 5 0 30 P24046 2.28e-70 Gamma-aminobutyric acid receptor subunit rho-1 (GABA(A) receptor subunit rho-1) (GABA(C) receptor) Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid signaling pathway [GO:0007214]; ion transmembrane transport [GO:0034220]; modulation of chemical synaptic transmission [GO:0050804]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165] GO:0004890; GO:0005231; GO:0005254; GO:0005886; GO:0007165; GO:0007214; GO:0007268; GO:0019904; GO:0030594; GO:0034220; GO:0034707; GO:0042391; GO:0042734; GO:0042802; GO:0043005; GO:0044877; GO:0045202; GO:0045211; GO:0050804; GO:0050877; GO:0098978; GO:0098982; GO:0099507; GO:1902476; GO:1902711; GO:1904315 48692 XM_029331436.2 141 6 455 305 567 NA NA NA NA NA NA 48693 XR_003828412.2 32 4 3 23 9 NA NA NA NA NA NA 48694 XR_006396755.1 1 0 71 123 0 NA NA NA NA NA NA 48695 XM_029349841.2 3505 2276 1740 2726 2898 Q7Z6B7 1.99e-133 SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho GTPase-activating protein 13) Homo sapiens (Human) negative regulation of cell migration [GO:0030336]; signal transduction [GO:0007165] GO:0005096; GO:0005737; GO:0005829; GO:0007165; GO:0030336 48696 XM_029323971.2 3 0 6 0 9 NA NA NA NA NA NA 48697 XM_029344965.2 357 124 153 125 700 O76360 0 cGMP-dependent protein kinase egl-4 (EC 2.7.11.12) (Egg-laying defective protein 4) Caenorhabditis elegans chemosensory behavior [GO:0007635]; chemotaxis [GO:0006935]; chemotropism [GO:0043577]; determination of adult lifespan [GO:0008340]; insulin receptor signaling pathway [GO:0008286]; larval feeding behavior [GO:0030536]; negative regulation of calcium-mediated signaling [GO:0050849]; negative regulation of cell growth [GO:0030308]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of cyclic nucleotide-gated ion channel activity [GO:1902160]; negative regulation of dauer larval development [GO:0061067]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of organ growth [GO:0046621]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; olfactory learning [GO:0008355]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cellular response to alcohol [GO:1905959]; positive regulation of cGMP-mediated signaling [GO:0010753]; positive regulation of chemotaxis [GO:0050921]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of gene expression [GO:0010628]; positive regulation of oviposition [GO:1901046]; protein phosphorylation [GO:0006468]; receptor guanylyl cyclase signaling pathway [GO:0007168]; regulation of eating behavior [GO:1903998]; regulation of gene expression [GO:0010468]; regulation of multicellular organism growth [GO:0040014]; regulation of oviposition [GO:0046662]; response to alcohol [GO:0097305]; response to hydrogen peroxide [GO:0042542]; response to odorant [GO:1990834]; response to oxygen levels [GO:0070482]; sensory perception of bitter taste [GO:0050913]; signal transduction [GO:0007165]; sleep [GO:0030431] GO:0004692; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006468; GO:0006935; GO:0007165; GO:0007168; GO:0007635; GO:0008286; GO:0008340; GO:0008355; GO:0010468; GO:0010628; GO:0010753; GO:0010754; GO:0018105; GO:0030308; GO:0030431; GO:0030512; GO:0030536; GO:0030553; GO:0040014; GO:0040015; GO:0042542; GO:0043577; GO:0046621; GO:0046662; GO:0046872; GO:0050849; GO:0050913; GO:0050921; GO:0051343; GO:0061067; GO:0070482; GO:0097305; GO:0106310; GO:1901046; GO:1902160; GO:1903998; GO:1905959; GO:1990834 48698 XM_044318764.1 844 138 128 436 245 NA NA NA NA NA NA 48699 XM_044315282.1 0 23 44 10 12 NA NA NA NA NA NA 48700 XR_006392645.1 52 46 44 8 68 NA NA NA NA NA NA 48701 XM_044324212.1 250 271 79 307 226 P35249 3.01e-162 Replication factor C subunit 4 (Activator 1 37 kDa subunit) (A1 37 kDa subunit) (Activator 1 subunit 4) (Replication factor C 37 kDa subunit) (RF-C 37 kDa subunit) (RFC37) Homo sapiens (Human) DNA duplex unwinding [GO:0032508]; DNA repair [GO:0006281]; DNA strand elongation involved in DNA replication [GO:0006271]; DNA-templated DNA replication [GO:0006261]; positive regulation of DNA-directed DNA polymerase activity [GO:1900264] GO:0003677; GO:0005524; GO:0005634; GO:0005654; GO:0005663; GO:0006261; GO:0006271; GO:0006281; GO:0016887; GO:0031390; GO:0031391; GO:0032508; GO:1900264 48702 XM_029350385.2 3422 3308 1695 3110 3156 Q99020 5.1e-47 Heterogeneous nuclear ribonucleoprotein A/B (hnRNP A/B) (CArG-binding factor-A) (CBF-A) Mus musculus (Mouse) epithelial to mesenchymal transition [GO:0001837]; mRNA modification [GO:0016556]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA demethylation [GO:1901537]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of cellular localization [GO:0060341]; regulation of gene expression [GO:0010468]; regulation of intracellular mRNA localization [GO:1904580] GO:0000122; GO:0001837; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0010468; GO:0016556; GO:0030425; GO:0044877; GO:0045293; GO:0045893; GO:0060341; GO:0071598; GO:0090575; GO:0099523; GO:1901537; GO:1904580; GO:1990124; GO:1990837; GO:1990904; GO:2000623 48703 XM_044323070.1 272 140 105 211 319 Q08DM8 3.53e-53 Translin (EC 3.1.-.-) (Component 3 of promoter of RISC) (C3PO) Bos taurus (Bovine) siRNA processing [GO:0030422] GO:0003697; GO:0003723; GO:0004519; GO:0005634; GO:0005654; GO:0005737; GO:0005783; GO:0030422; GO:0042802; GO:0043565; GO:1902555 48704 XM_029323796.2 0 35 11 0 101 Q5F457 3.12e-29 WW domain-binding protein 4 (WBP-4) Gallus gallus (Chicken) mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380] GO:0000398; GO:0003723; GO:0005634; GO:0008270; GO:0008380; GO:0016607; GO:0071005; GO:0071011 48705 XM_044321819.1 32 23 22 161 176 NA NA NA NA NA NA 48706 XR_006394628.1 11 0 0 0 0 A0A2B4SES9 9.04e-114 NA NA NA NA 48707 XM_044310899.1 6 14 0 0 0 NA NA NA NA NA NA 48708 XR_006391656.1 323 123 76 237 382 NA NA NA NA NA NA 48709 XM_029340766.2 3 0 0 0 7 NA NA NA NA NA NA 48710 XR_003826079.2 112 102 40 41 63 NA NA NA NA NA NA 48711 XM_029327415.2 675 554 417 559 567 Q4G5Y1 9.6e-83 Kelch domain-containing protein 2 (Endothelial differentiation inhibitory protein TNG) Mus musculus (Mouse) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process via the C-end degron rule pathway [GO:0140627] GO:0005634; GO:0005654; GO:0016567; GO:0016604; GO:0031462; GO:0031965; GO:0043161; GO:0140627; GO:1990756 48712 XR_006392534.1 5 0 8 0 5 NA NA NA NA NA NA 48713 XM_029357993.2 5084 3843 2049 3904 2982 P56101 5.09e-45 DnaJ homolog subfamily C member 5 (CCCS1) (Cysteine string protein) (CSP) Tetronarce californica (Pacific electric ray) (Torpedo californica) NA GO:0005829; GO:0005886; GO:0016020; GO:0042470; GO:0042584 48714 XM_044320120.1 839 501 288 652 402 Q9NU02 0 Ankyrin repeat and EF-hand domain-containing protein 1 (Ankyrin repeat domain-containing protein 5) Homo sapiens (Human) NA GO:0005509 48715 XM_029342938.2 0 28 0 1 5 NA NA NA NA NA NA 48716 XM_044308079.1 193 68 208 160 151 Q0E908 9.52e-39 Hillarin (D-Hillarin) (D-hil) Drosophila melanogaster (Fruit fly) NA GO:0005938; GO:0032154; GO:0046872 48717 XR_006396256.1 50 9 23 15 2 NA NA NA NA NA NA 48718 XM_044322497.1 2955 2046 1452 3083 3234 NA NA NA NA NA NA 48719 XM_029338990.2 116 72 57 85 72 P54131 9.49e-79 Neuronal acetylcholine receptor subunit alpha-7 Bos taurus (Bovine) calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; cognition [GO:0050890]; ion transmembrane transport [GO:0034220]; negative regulation of tumor necrosis factor production [GO:0032720]; nervous system process [GO:0050877]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAPK cascade [GO:0043410]; regulation of membrane potential [GO:0042391]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271] GO:0001540; GO:0001666; GO:0005231; GO:0005886; GO:0005892; GO:0006816; GO:0006874; GO:0007165; GO:0007268; GO:0007271; GO:0008284; GO:0015464; GO:0015643; GO:0017081; GO:0022848; GO:0030594; GO:0032720; GO:0034220; GO:0035094; GO:0042166; GO:0042391; GO:0042803; GO:0043005; GO:0043410; GO:0045202; GO:0045211; GO:0045766; GO:0050877; GO:0050890; GO:1904315 48720 XM_029334719.2 78 78 104 132 136 Q9JMA7 3.95e-99 Cytochrome P450 3A41 (EC 1.14.14.1) Mus musculus (Mouse) alkaloid catabolic process [GO:0009822]; estrogen metabolic process [GO:0008210]; lipid hydroxylation [GO:0002933]; oxidative demethylation [GO:0070989]; regulation of gene expression [GO:0010468]; response to bacterium [GO:0009617]; retinoic acid metabolic process [GO:0042573]; steroid metabolic process [GO:0008202]; xenobiotic catabolic process [GO:0042178] GO:0002933; GO:0004497; GO:0005506; GO:0005789; GO:0008202; GO:0008210; GO:0008395; GO:0008401; GO:0009617; GO:0009822; GO:0010468; GO:0016491; GO:0020037; GO:0032451; GO:0042178; GO:0042573; GO:0043231; GO:0050649; GO:0070330; GO:0070989; GO:0101020 48721 XM_029330181.2 554 534 250 442 380 NA NA NA NA NA NA 48722 XM_044312537.1 0 0 11 0 3 NA NA NA NA NA NA 48723 XM_029343011.2 603 651 233 1076 817 E7FAM5 3.62e-89 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 48724 XR_006393902.1 41 2 25 5 151 NA NA NA NA NA NA 48725 XM_029348939.2 15 116 0 50 0 O54852 5.01e-102 Potassium voltage-gated channel subfamily H member 7 (Ether-a-go-go-related gene potassium channel 3) (ERG-3) (Eag-related protein 3) (Ether-a-go-go-related protein 3) (Voltage-gated potassium channel subunit Kv11.3) Rattus norvegicus (Rat) circadian rhythm [GO:0007623]; membrane repolarization during action potential [GO:0086011]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391] GO:0005242; GO:0005249; GO:0005267; GO:0005886; GO:0006813; GO:0007623; GO:0034765; GO:0042391; GO:0044877; GO:0071805; GO:0086011 48726 XM_029356254.2 1686 1930 994 1230 1212 Q9UK45 5.47e-48 U6 snRNA-associated Sm-like protein LSm7 Homo sapiens (Human) mRNA splicing, via spliceosome [GO:0000398]; nuclear-transcribed mRNA catabolic process [GO:0000956] GO:0000398; GO:0000956; GO:0005634; GO:0005654; GO:0005688; GO:0005689; GO:0005829; GO:0017070; GO:0046540; GO:0071004; GO:0071005; GO:0071013; GO:0097526; GO:0120115; GO:1990726; GO:1990904 48727 XM_044320368.1 1 0 2 38 27 NA NA NA NA NA NA 48728 XM_029323685.2 1346 765 713 650 619 Q9QXT1 8.08e-77 Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide (mDAPP1) (B lymphocyte adapter protein Bam32) (B-cell adapter molecule of 32 kDa) Mus musculus (Mouse) NA GO:0005547; GO:0005737; GO:0005886; GO:0043325 48729 XM_029337422.2 26 17 11 18 0 NA NA NA NA NA NA 48730 XM_029343135.2 26 188 138 138 105 Q3MIE0 4.67e-120 Enoyl-CoA hydratase domain-containing protein 3, mitochondrial Rattus norvegicus (Rat) fatty acid metabolic process [GO:0006631]; positive regulation of cellular response to insulin stimulus [GO:1900078] GO:0004300; GO:0005739; GO:0006631; GO:0016836; GO:1900078 48731 XM_044327234.1 737 356 538 810 620 Q803R5 0 Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 (EC 2.1.1.57) (Cap methyltransferase 1) (Cap1 2'O-ribose methyltransferase 1) (MTr1) (FtsJ methyltransferase domain-containing protein 2) Danio rerio (Zebrafish) (Brachydanio rerio) 7-methylguanosine mRNA capping [GO:0006370]; cap1 mRNA methylation [GO:0097309]; mRNA methylation [GO:0080009] GO:0003676; GO:0004483; GO:0005634; GO:0005737; GO:0006370; GO:0080009; GO:0097309 48732 XM_044328086.1 15 1 2 3 4 NA NA NA NA NA NA 48733 XM_029339611.2 980 792 676 786 806 NA NA NA NA NA NA 48734 XM_044311698.1 265 0 0 54 279 Q96T58 7.79e-62 Msx2-interacting protein (SMART/HDAC1-associated repressor protein) (SPEN homolog) Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of neurogenesis [GO:0050769]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0003677; GO:0003714; GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0006357; GO:0007219; GO:0017053; GO:0045892; GO:0050769; GO:0061629; GO:0070062 48735 XM_044311698.1 265 0 0 54 279 Q96T58 5.91e-59 Msx2-interacting protein (SMART/HDAC1-associated repressor protein) (SPEN homolog) Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of neurogenesis [GO:0050769]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0003677; GO:0003714; GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0006357; GO:0007219; GO:0017053; GO:0045892; GO:0050769; GO:0061629; GO:0070062 48736 XR_006397803.1 108 45 6 1 2 NA NA NA NA NA NA 48737 XM_029333938.2 6 17 36 24 20 P81439 2.28e-30 Equistatin (EI) (Cysteine proteinase inhibitor) Actinia equina (Beadlet anemone) negative regulation of peptidase activity [GO:0010466] GO:0004869; GO:0005576; GO:0010466 48738 XM_029333938.2 6 17 36 24 20 P81439 1.26e-26 Equistatin (EI) (Cysteine proteinase inhibitor) Actinia equina (Beadlet anemone) negative regulation of peptidase activity [GO:0010466] GO:0004869; GO:0005576; GO:0010466 48739 XM_029333938.2 6 17 36 24 20 P81439 3.76e-25 Equistatin (EI) (Cysteine proteinase inhibitor) Actinia equina (Beadlet anemone) negative regulation of peptidase activity [GO:0010466] GO:0004869; GO:0005576; GO:0010466 48740 XM_029333938.2 6 17 36 24 20 P81439 3e-22 Equistatin (EI) (Cysteine proteinase inhibitor) Actinia equina (Beadlet anemone) negative regulation of peptidase activity [GO:0010466] GO:0004869; GO:0005576; GO:0010466 48741 XR_006395402.1 39 183 30 13 29 NA NA NA NA NA NA 48742 XM_029339337.2 872 583 275 574 557 O18894 0 H(+)/Cl(-) exchange transporter 3 (Chloride channel protein 3) (ClC-3) (Chloride transporter ClC-3) Oryctolagus cuniculus (Rabbit) NA GO:0005247; GO:0005524; GO:0005765; GO:0005769; GO:0005770; GO:0005794; GO:0005886; GO:0010008; GO:0012506; GO:0015297; GO:0030165; GO:0031901; GO:0031902; GO:0055037 48743 XM_044325475.1 21 0 0 69 9 Q80SY4 2.17e-49 E3 ubiquitin-protein ligase MIB1 (EC 2.3.2.27) (DAPK-interacting protein 1) (DIP-1) (Mind bomb homolog 1) (RING-type E3 ubiquitin transferase MIB1) Mus musculus (Mouse) blood vessel development [GO:0001568]; endocytosis [GO:0006897]; heart development [GO:0007507]; heart looping [GO:0001947]; in utero embryonic development [GO:0001701]; negative regulation of neuron differentiation [GO:0045665]; neural tube formation [GO:0001841]; neuron differentiation [GO:0030182]; Notch signaling pathway [GO:0007219]; positive regulation of endocytosis [GO:0045807]; protein ubiquitination [GO:0016567]; somitogenesis [GO:0001756]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0001568; GO:0001701; GO:0001756; GO:0001841; GO:0001947; GO:0004842; GO:0005737; GO:0005813; GO:0005886; GO:0006511; GO:0006897; GO:0007219; GO:0007507; GO:0008270; GO:0014069; GO:0016567; GO:0030182; GO:0031410; GO:0045665; GO:0045807 48744 XR_006391528.1 21 14 10 8 3 NA NA NA NA NA NA 48745 XR_003825159.2 1152 780 634 479 61 NA NA NA NA NA NA 48746 XR_006393256.1 112 17 52 72 99 NA NA NA NA NA NA 48747 XM_044310552.1 7 2 5 3 4 NA NA NA NA NA NA 48748 XM_029344690.2 1219 516 391 667 673 Q3ZBY3 3.33e-60 Calretinin (CR) Bos taurus (Bovine) NA GO:0005509 48749 XM_029344690.2 1219 516 391 667 673 Q3ZBY3 3.74e-21 Calretinin (CR) Bos taurus (Bovine) NA GO:0005509 48750 XM_029326917.2 18760 15971 11162 16500 11356 NA NA NA NA NA NA 48751 XM_029350992.2 106 92 22 302 251 NA NA NA NA NA NA 48752 XM_029349401.2 0 0 0 69 0 NA NA NA NA NA NA 48753 XM_029343768.2 2977 1798 1323 2187 3500 A1L224 4.58e-45 Cyclic AMP-responsive element-binding protein 3-like protein 2 (cAMP-responsive element-binding protein 3-like protein 2) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3-like protein 2] Danio rerio (Zebrafish) (Brachydanio rerio) cartilage development [GO:0051216]; chondrocyte differentiation [GO:0002062]; regulation of ER to Golgi vesicle-mediated transport [GO:0060628]; regulation of extracellular matrix constituent secretion [GO:0003330]; regulation of transcription by RNA polymerase II [GO:0006357]; response to endoplasmic reticulum stress [GO:0034976]; response to unfolded protein [GO:0006986] GO:0000976; GO:0000981; GO:0002062; GO:0003330; GO:0005634; GO:0005783; GO:0005789; GO:0006357; GO:0006986; GO:0034976; GO:0035497; GO:0051216; GO:0060628 48754 XR_006397809.1 0 6 0 11 0 NA NA NA NA NA NA 48755 XM_044315392.1 192 454 398 111 161 P15428 4.07e-48 15-hydroxyprostaglandin dehydrogenase [NAD(+)] (15-PGDH) (EC 1.1.1.141) (Eicosanoid/docosanoid dehydrogenase [NAD(+)]) (EC 1.1.1.-, EC 1.1.1.232) (Prostaglandin dehydrogenase 1) (Short chain dehydrogenase/reductase family 36C member 1) Homo sapiens (Human) ductus arteriosus closure [GO:0097070]; female pregnancy [GO:0007565]; kidney development [GO:0001822]; lipoxygenase pathway [GO:0019372]; negative regulation of cell cycle [GO:0045786]; ovulation [GO:0030728]; parturition [GO:0007567]; positive regulation of apoptotic process [GO:0043065]; positive regulation of vascular associated smooth muscle cell proliferation [GO:1904707]; prostaglandin metabolic process [GO:0006693]; regulation of prostaglandin catabolic process [GO:1905828]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; thrombin-activated receptor signaling pathway [GO:0070493]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001822; GO:0004957; GO:0005654; GO:0005737; GO:0005829; GO:0006693; GO:0007179; GO:0007565; GO:0007567; GO:0016323; GO:0016404; GO:0016616; GO:0019372; GO:0030728; GO:0032355; GO:0032496; GO:0042802; GO:0043065; GO:0045471; GO:0045786; GO:0051287; GO:0070062; GO:0070403; GO:0070493; GO:0097070; GO:1904707; GO:1905828 48756 XM_029353107.2 717 485 406 678 753 NA NA NA NA NA NA 48757 XM_044315112.1 20 35 14 59 69 NA NA NA NA NA NA 48758 XR_006396832.1 14 771 0 46 359 NA NA NA NA NA NA 48759 XM_044320045.1 76 215 64 217 201 B8EIZ7 1.12e-152 NA NA NA NA 48760 XM_044327916.1 0 0 0 227 0 P70490 2.03e-49 Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (O-acetyl GD3 ganglioside synthase) (AGS) (SED1) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338] GO:0001525; GO:0001786; GO:0002080; GO:0005178; GO:0005615; GO:0006910; GO:0006911; GO:0007155; GO:0007338; GO:0008284; GO:0008429; GO:0009897; GO:0019897; GO:0043277; GO:0043627; GO:0050766 48761 XM_029352195.2 18 80 46 49 124 NA NA NA NA NA NA 48762 XM_044329346.1 32 0 0 11 27 NA NA NA NA NA NA 48763 XR_006398016.1 13 0 6 23 88 NA NA NA NA NA NA 48764 XM_029356258.2 812 633 434 557 1200 NA NA NA NA NA NA 48765 XM_044311165.1 64 8 135 4 345 P35067 4.06e-79 Histone H2B Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 48766 XR_006391336.1 850 602 330 521 657 A7SUU7 3.96e-169 MAU2 chromatid cohesion factor homolog (Cohesin loading complex subunit SCC4 homolog) Nematostella vectensis (Starlet sea anemone) cell division [GO:0051301]; maintenance of mitotic sister chromatid cohesion [GO:0034088] GO:0000785; GO:0003690; GO:0005634; GO:0005654; GO:0032116; GO:0034088; GO:0051301 48767 XR_006391336.1 850 602 330 521 657 A7SUU7 3.96e-169 MAU2 chromatid cohesion factor homolog (Cohesin loading complex subunit SCC4 homolog) Nematostella vectensis (Starlet sea anemone) cell division [GO:0051301]; maintenance of mitotic sister chromatid cohesion [GO:0034088] GO:0000785; GO:0003690; GO:0005634; GO:0005654; GO:0032116; GO:0034088; GO:0051301 48768 XR_006391336.1 850 602 330 521 657 A7SUU7 3.96e-169 MAU2 chromatid cohesion factor homolog (Cohesin loading complex subunit SCC4 homolog) Nematostella vectensis (Starlet sea anemone) cell division [GO:0051301]; maintenance of mitotic sister chromatid cohesion [GO:0034088] GO:0000785; GO:0003690; GO:0005634; GO:0005654; GO:0032116; GO:0034088; GO:0051301 48769 XM_029333995.2 84 91 36 170 99 Q6Q4G4 1.43e-180 Angiotensin-converting enzyme (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (TtACE) Theromyzon tessulatum (Duck leech) proteolysis [GO:0006508] GO:0004180; GO:0005615; GO:0006508; GO:0008237; GO:0008241; GO:0016020; GO:0046872 48770 XM_044313427.1 1 726 0 1 3 NA NA NA NA NA NA 48771 XM_044323100.1 1949 482 963 816 1387 NA NA NA NA NA NA 48772 XM_029341374.2 0 0 395 2 5 Q98993 4.32e-52 Verrucotoxin subunit beta (VTX subunit beta) Synanceia verrucosa (Reef stonefish) hemolysis in another organism [GO:0044179] GO:0005246; GO:0005576; GO:0015459; GO:0044179; GO:0090729 48773 XM_029338799.2 3243 2096 1956 5126 4230 B3EWZ7 7.56e-102 Threonine-rich protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 48774 XM_029348105.2 603 459 309 355 298 A6QLU1 0 Glycerol-3-phosphate dehydrogenase, mitochondrial (GPD-M) (GPDH-M) (EC 1.1.5.3) Bos taurus (Bovine) glycerol catabolic process [GO:0019563]; glycerol-3-phosphate metabolic process [GO:0006072] GO:0004368; GO:0005509; GO:0005739; GO:0006072; GO:0009331; GO:0019563; GO:0052591 48775 XR_006395635.1 257 181 233 497 374 NA NA NA NA NA NA 48776 XM_029327929.2 22 0 1 0 7 NA NA NA NA NA NA 48777 XM_044317863.1 761 626 525 1281 1178 Q86US8 2.73e-139 Telomerase-binding protein EST1A (EC 3.1.-.-) (Ever shorter telomeres 1A) (hEST1A) (Nonsense mediated mRNA decay factor SMG6) (Smg-6 homolog) (hSmg5/7a) Homo sapiens (Human) mRNA export from nucleus [GO:0006406]; negative regulation of telomere capping [GO:1904354]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of dephosphorylation [GO:0035303]; regulation of telomerase activity [GO:0051972]; regulation of telomere maintenance [GO:0032204]; regulation of telomere maintenance via telomerase [GO:0032210] GO:0000184; GO:0000781; GO:0003723; GO:0004521; GO:0005634; GO:0005697; GO:0005730; GO:0005737; GO:0005829; GO:0006406; GO:0032204; GO:0032210; GO:0035303; GO:0042162; GO:0043021; GO:0046872; GO:0051972; GO:0070034; GO:0070182; GO:1904354 48778 XM_044319952.1 58 90 73 69 77 P35061 1.26e-55 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 48779 XR_006397543.1 7 89 10 2 57 NA NA NA NA NA NA 48780 XM_029324642.2 92 76 29 46 98 Q8VEJ1 7.89e-144 GPN-loop GTPase 2 (ATP-binding domain 1 family member B) Mus musculus (Mouse) NA GO:0003924; GO:0005525 48781 XM_044312850.1 0 41 0 0 244 Q9JMB7 0 Piwi-like protein 1 (EC 3.1.26.-) Mus musculus (Mouse) meiotic cell cycle [GO:0051321]; negative regulation of transposition [GO:0010529]; piRNA processing [GO:0034587]; regulation of translation [GO:0006417]; RNA-mediated gene silencing [GO:0031047]; sperm DNA condensation [GO:0035092]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283] GO:0003723; GO:0003727; GO:0003729; GO:0004521; GO:0005634; GO:0005737; GO:0005829; GO:0006417; GO:0007283; GO:0007286; GO:0010529; GO:0019901; GO:0031047; GO:0033391; GO:0034584; GO:0034587; GO:0035092; GO:0043186; GO:0046872; GO:0051321; GO:0097433; GO:0140262; GO:1905538 48782 XM_044311263.1 0 0 0 8 0 Q9VBW3 3.13e-62 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 48783 XM_044325857.1 48 0 75 0 31 NA NA NA NA NA NA 48784 XM_029325806.2 84 186 50 248 277 NA NA NA NA NA NA 48785 XM_029333851.2 1145 910 718 999 1046 Q8K4J6 1.31e-25 Myocardin-related transcription factor A (MRTF-A) (Basic SAP coiled-coil transcription activator) (MKL/myocardin-like protein 1) (Megakaryoblastic leukemia 1 protein homolog) (Megakaryocytic acute leukemia protein homolog) Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; forebrain development [GO:0030900]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; smooth muscle cell differentiation [GO:0051145]; wound healing, spreading of cells [GO:0044319] GO:0000976; GO:0001764; GO:0003700; GO:0003713; GO:0003779; GO:0003785; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006357; GO:0030036; GO:0030900; GO:0031175; GO:0043154; GO:0043522; GO:0044319; GO:0045893; GO:0045944; GO:0051145; GO:0060090; GO:1902895; GO:2001234 48786 XM_044318539.1 1405 893 742 1691 1963 P16066 0 Atrial natriuretic peptide receptor 1 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type A) (ANP-A) (ANPR-A) (NPR-A) (Guanylate cyclase A) (GC-A) Homo sapiens (Human) blood vessel diameter maintenance [GO:0097746]; body fluid secretion [GO:0007589]; cell surface receptor signaling pathway [GO:0007166]; cGMP biosynthetic process [GO:0006182]; cGMP-mediated signaling [GO:0019934]; dopamine metabolic process [GO:0042417]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell growth [GO:0030308]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of cGMP-mediated signaling [GO:0010753]; positive regulation of renal sodium excretion [GO:0035815]; positive regulation of urine volume [GO:0035810]; protein phosphorylation [GO:0006468]; receptor guanylyl cyclase signaling pathway [GO:0007168]; regulation of blood pressure [GO:0008217]; regulation of vascular permeability [GO:0043114]; signal transduction [GO:0007165] GO:0001653; GO:0004383; GO:0004672; GO:0005524; GO:0005525; GO:0005886; GO:0006182; GO:0006468; GO:0007165; GO:0007166; GO:0007168; GO:0007589; GO:0008217; GO:0008528; GO:0010753; GO:0016525; GO:0016941; GO:0017046; GO:0019934; GO:0030308; GO:0035810; GO:0035815; GO:0042417; GO:0042562; GO:0043114; GO:0043235; GO:0048662; GO:0097746; GO:1990620 48787 XM_029328501.2 15 18 5 134 22 NA NA NA NA NA NA 48788 XM_029330945.2 1983 1188 758 1135 1396 Q8C0J2 3.66e-131 Autophagy-related protein 16-1 (APG16-like 1) Mus musculus (Mouse) autophagosome assembly [GO:0000045]; C-terminal protein lipidation [GO:0006501]; corpus callosum development [GO:0022038]; defense response to virus [GO:0051607]; hippocampus development [GO:0021766]; lysosomal microautophagy [GO:0016237]; macroautophagy [GO:0016236]; negative stranded viral RNA replication [GO:0039689]; positive regulation of autophagy [GO:0010508]; protein lipidation [GO:0006497]; protein lipidation involved in autophagosome assembly [GO:0061739]; protein localization to phagophore assembly site [GO:0034497]; protein transport [GO:0015031]; xenophagy [GO:0098792] GO:0000045; GO:0000421; GO:0005737; GO:0005776; GO:0005829; GO:0005930; GO:0006497; GO:0006501; GO:0010508; GO:0015031; GO:0016236; GO:0016237; GO:0021766; GO:0022038; GO:0034045; GO:0034274; GO:0034497; GO:0036020; GO:0039689; GO:0042802; GO:0051020; GO:0051607; GO:0061739; GO:0097225; GO:0098792; GO:0120095 48789 XR_006392938.1 41 2 25 5 151 NA NA NA NA NA NA 48790 XM_029335996.2 334 182 39 181 89 NA NA NA NA NA NA 48791 XM_029339401.2 379 6 88 51 146 P57102 6.14e-22 Heart- and neural crest derivatives-expressed protein 2 (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND) Danio rerio (Zebrafish) (Brachydanio rerio) cardiac muscle cell differentiation [GO:0055007]; cardioblast differentiation [GO:0010002]; cardiocyte differentiation [GO:0035051]; cardiogenic plate morphogenesis [GO:0003142]; determination of intestine left/right asymmetry [GO:0071908]; developmental process [GO:0032502]; embryonic heart tube formation [GO:0003144]; embryonic pectoral fin morphogenesis [GO:0035118]; embryonic viscerocranium morphogenesis [GO:0048703]; heart contraction [GO:0060047]; heart development [GO:0007507]; heart looping [GO:0001947]; heart morphogenesis [GO:0003007]; noradrenergic neuron differentiation [GO:0003357]; polarized epithelial cell differentiation [GO:0030859]; proepicardium development [GO:0003342]; regulation of transcription by RNA polymerase II [GO:0006357]; sympathetic nervous system development [GO:0048485]; thyroid gland development [GO:0030878] GO:0000977; GO:0000981; GO:0001947; GO:0003007; GO:0003142; GO:0003144; GO:0003342; GO:0003357; GO:0005634; GO:0006357; GO:0007507; GO:0010002; GO:0030859; GO:0030878; GO:0032502; GO:0035051; GO:0035118; GO:0046983; GO:0048485; GO:0048703; GO:0055007; GO:0060047; GO:0071908 48792 XR_006397900.1 637 390 458 538 656 NA NA NA NA NA NA 48793 XM_044319695.1 423 0 114 0 0 Q3V050 8.85e-88 Multidrug and toxin extrusion protein 2 (MATE-2) (mMATE-2) (H(+)/organic cation antiporter kidney-specific) (Solute carrier family 47 member 2) Mus musculus (Mouse) organic cation transport [GO:0015695]; xenobiotic detoxification by transmembrane export across the plasma membrane [GO:1990961] GO:0005886; GO:0015101; GO:0015179; GO:0015297; GO:0015299; GO:0015695; GO:0016020; GO:0016323; GO:0016324; GO:0022857; GO:0042910; GO:0061459; GO:1990961 48794 XM_029352582.2 0 12 0 0 0 NA NA NA NA NA NA 48795 XM_044316897.1 0 0 0 0 15 P16610 2.16e-32 Substance-K receptor (SKR) (NK-2 receptor) (NK-2R) (Neurokinin A receptor) (Tachykinin receptor 2) Rattus norvegicus (Rat) intestine smooth muscle contraction [GO:0014827]; negative regulation of luteinizing hormone secretion [GO:0033685]; operant conditioning [GO:0035106]; positive regulation of acetylcholine secretion, neurotransmission [GO:0014057]; positive regulation of flagellated sperm motility [GO:1902093]; positive regulation of ion transport [GO:0043270]; positive regulation of uterine smooth muscle contraction [GO:0070474]; positive regulation of vascular permeability [GO:0043117]; prolactin secretion [GO:0070459]; regulation of uterine smooth muscle contraction [GO:0070472]; response to electrical stimulus [GO:0051602] GO:0004995; GO:0005886; GO:0014057; GO:0014827; GO:0016020; GO:0016497; GO:0033685; GO:0035106; GO:0036126; GO:0043117; GO:0043270; GO:0051602; GO:0061827; GO:0070459; GO:0070472; GO:0070474; GO:0097225; GO:1902093 48796 XM_029346765.2 13 16 3 40 24 NA NA NA NA NA NA 48797 XM_044321512.1 32 6 43 4 40 NA NA NA NA NA NA 48798 XR_003824163.2 127 118 117 105 106 NA NA NA NA NA NA 48799 XM_029343464.2 1 5 0 0 33 NA NA NA NA NA NA 48800 XM_044324176.1 0 25 32 73 46 NA NA NA NA NA NA 48801 XM_044311681.1 3 0 1 1 24 B8VIU6 1.94e-59 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 48802 XM_044319249.1 2891 1372 1794 2073 2199 Q8IS14 1.06e-39 Ras guanine nucleotide exchange factor J (RasGEF domain-containing protein J) Dictyostelium discoideum (Social amoeba) positive regulation of GTPase activity [GO:0043547]; Ras protein signal transduction [GO:0007265] GO:0005085; GO:0005886; GO:0007265; GO:0043547 48803 XM_044319690.1 64 25 18 60 63 E7FAM5 4.58e-90 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 48804 XM_044317528.1 114 17 11 47 169 NA NA NA NA NA NA 48805 XM_029334849.2 0 0 21 16 25 NA NA NA NA NA NA 48806 XM_029357213.2 0 47 148 239 265 Q9HCJ3 1.64e-44 Ribonucleoprotein PTB-binding 2 (Protein raver-2) Homo sapiens (Human) regulation of alternative mRNA splicing, via spliceosome [GO:0000381] GO:0000381; GO:0003723; GO:0003729; GO:0005634; GO:0005737 48807 XM_044307681.1 556 209 616 501 368 NA NA NA NA NA NA 48808 XM_029329216.2 545 254 310 289 316 P57678 6.13e-21 Gem-associated protein 4 (Gemin-4) (Component of gems 4) (p97) Homo sapiens (Human) rRNA processing [GO:0006364]; spliceosomal snRNP assembly [GO:0000387] GO:0000387; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0006364; GO:0015030; GO:0016020; GO:0016604; GO:0030532; GO:0032797; GO:0034719; GO:0043021; GO:0070062; GO:0097504 48809 XR_003824671.2 17 6 40 73 58 NA NA NA NA NA NA 48810 XM_029348596.2 204 0 172 197 352 Q7TPD0 0 Integrator complex subunit 3 (Int3) (SOSS complex subunit A) (Sensor of single-strand DNA complex subunit A) (SOSS-A) (Sensor of ssDNA subunit A) Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; mitotic G2/M transition checkpoint [GO:0044818]; response to ionizing radiation [GO:0010212]; snRNA processing [GO:0016180] GO:0000724; GO:0005634; GO:0005737; GO:0006281; GO:0006974; GO:0010212; GO:0016180; GO:0032039; GO:0035861; GO:0044818; GO:0070876 48811 XM_044308991.1 22 0 0 0 0 NA NA NA NA NA NA 48812 XM_029349796.2 888 821 154 0 0 NA NA NA NA NA NA 48813 XM_044313214.1 51 1 7 19 28 NA NA NA NA NA NA 48814 XM_044327761.1 16 0 28 9 120 NA NA NA NA NA NA 48815 XM_029339643.2 1607 581 1003 964 869 Q9WYP5 9.63e-71 Myo-inositol 2-dehydrogenase (EC 1.1.1.18) Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) inositol metabolic process [GO:0006020]; NADPH regeneration [GO:0006740] GO:0000166; GO:0006020; GO:0006740; GO:0016491; GO:0050112 48816 XM_029344587.2 8399 6310 3112 6666 8225 P97742 0 Carnitine O-palmitoyltransferase 1, liver isoform (CPT1-L) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, liver isoform) (CPT I) (CPTI-L) (Carnitine palmitoyltransferase 1A) Mus musculus (Mouse) carnitine metabolic process [GO:0009437]; cellular response to fatty acid [GO:0071398]; eating behavior [GO:0042755]; epithelial cell differentiation [GO:0030855]; fatty acid beta-oxidation [GO:0006635]; fatty acid metabolic process [GO:0006631]; glucose metabolic process [GO:0006006]; lipid localization [GO:0010876]; liver regeneration [GO:0097421]; long-chain fatty acid metabolic process [GO:0001676]; positive regulation of fatty acid beta-oxidation [GO:0032000]; regulation of fatty acid oxidation [GO:0046320]; regulation of insulin secretion [GO:0050796]; regulation of lipid storage [GO:0010883]; response to alkaloid [GO:0043279]; response to antibiotic [GO:0046677]; response to ethanol [GO:0045471]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]; response to tetrachloromethane [GO:1904772]; response to xenobiotic stimulus [GO:0009410]; triglyceride metabolic process [GO:0006641] GO:0001676; GO:0004095; GO:0005739; GO:0005741; GO:0005743; GO:0006006; GO:0006631; GO:0006635; GO:0006641; GO:0009410; GO:0009437; GO:0010876; GO:0010883; GO:0014070; GO:0016020; GO:0030855; GO:0031667; GO:0032000; GO:0042755; GO:0042802; GO:0043231; GO:0043279; GO:0045471; GO:0046320; GO:0046677; GO:0050796; GO:0071398; GO:0097421; GO:1904772; GO:1990698 48817 XM_044324343.1 4400 2397 3546 5833 5444 NA NA NA NA NA NA 48818 XM_044316349.1 30 0 7 5 23 Q5SVZ6 6.26e-27 Zinc finger MYM-type protein 1 Homo sapiens (Human) NA GO:0005634; GO:0008270; GO:0046983 48819 XM_044315152.1 17 13 57 17 158 NA NA NA NA NA NA 48820 XM_044308519.1 14 0 0 20 6 O15014 1.8e-22 Zinc finger protein 609 Homo sapiens (Human) muscle organ development [GO:0007517]; positive regulation of neuron migration [GO:2001224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of myoblast proliferation [GO:2000291]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0005634; GO:0005654; GO:0006357; GO:0007517; GO:0045944; GO:0046872; GO:1990841; GO:2000291; GO:2001224 48821 XM_044325867.1 14 14 0 18 50 NA NA NA NA NA NA 48822 XM_044320911.1 9 0 10 8 43 NA NA NA NA NA NA 48823 XM_044315179.1 501 71 0 51 71 NA NA NA NA NA NA 48824 XR_006395963.1 19 17 5 31 14 Q99570 4.93e-30 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 48825 XR_006395963.1 19 17 5 31 14 Q99570 4.93e-30 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 48826 XM_044324887.1 148 143 62 209 179 NA NA NA NA NA NA 48827 XM_044325902.1 34 60 42 37 126 NA NA NA NA NA NA 48828 XM_029340931.2 41535 36676 35438 53872 63075 Q9YHT2 3.5e-157 Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (EC 1.3.5.1) (Iron-sulfur subunit of complex II) (Ip) Gallus gallus (Chicken) tricarboxylic acid cycle [GO:0006099] GO:0005743; GO:0005749; GO:0006099; GO:0008177; GO:0009055; GO:0046872; GO:0048039; GO:0051537; GO:0051538; GO:0051539; GO:0102040 48829 XM_044321615.1 719 269 321 204 456 Q7RTR2 1.26e-29 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 48830 XM_029335267.2 0 0 0 62 185 Q90WU3 0 ATP-dependent RNA helicase DDX1 (EC 3.6.4.13) (DEAD box protein 1) Gallus gallus (Chicken) DNA duplex unwinding [GO:0032508]; double-strand break repair [GO:0006302]; mRNA processing [GO:0006397]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388] GO:0003677; GO:0003682; GO:0003712; GO:0003724; GO:0004518; GO:0004527; GO:0005524; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0006302; GO:0006388; GO:0006397; GO:0008143; GO:0016887; GO:0032508; GO:0033677; GO:0072669 48831 XM_044309017.1 310 421 155 217 374 Q3UQ28 1.95e-30 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 48832 XM_044309017.1 310 421 155 217 374 Q3UQ28 8.51e-24 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 48833 XM_044322072.1 36 10 0 0 0 Q5R9I3 1.59e-33 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cellular response to glucose starvation [GO:0042149]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; protein phosphorylation [GO:0006468] GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005930; GO:0006468; GO:0016236; GO:0035032; GO:0042149; GO:0045324; GO:0106310 48834 XM_029358262.2 284 176 134 175 109 NA NA NA NA NA NA 48835 XM_029338674.2 1341 1601 1072 1205 980 P40639 7.07e-30 SRY-related protein AES4 Alligator mississippiensis (American alligator) NA GO:0003677; GO:0005634 48836 XM_029335805.2 139 84 0 244 223 B3EWZ8 0 Ectin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 48837 XM_029332701.2 259 133 8 0 26 NA NA NA NA NA NA 48838 XM_029344344.2 423 111 274 248 188 NA NA NA NA NA NA 48839 XM_044308931.1 17 0 22 6 59 NA NA NA NA NA NA 48840 XM_029335853.2 19 356 87 139 124 Q75V66 0 Anoctamin-5 (Gnathodiaphyseal dysplasia 1 protein) (Transmembrane protein 16E) Homo sapiens (Human) chloride transmembrane transport [GO:1902476]; chloride transport [GO:0006821]; ion transmembrane transport [GO:0034220]; transmembrane transport [GO:0055085] GO:0005229; GO:0005254; GO:0005789; GO:0005886; GO:0006821; GO:0031982; GO:0034220; GO:0046983; GO:0055085; GO:1902476 48841 XM_044312728.1 139 33 33 268 127 NA NA NA NA NA NA 48842 XM_029353273.2 48 82 100 0 54 Q8N9I5 5.41e-79 Fatty acid desaturase 6 (EC 1.14.19.-) Homo sapiens (Human) fatty acid biosynthetic process [GO:0006633]; lipid metabolic process [GO:0006629] GO:0006629; GO:0006633; GO:0016020; GO:0016717 48843 XR_006396435.1 101 34 64 4 184 NA NA NA NA NA NA 48844 XM_044321937.1 1489 1357 772 1351 1604 Q6AZA0 0 Acetyl-CoA acetyltransferase, mitochondrial (EC 2.3.1.9) (Acetoacetyl-CoA thiolase) Danio rerio (Zebrafish) (Brachydanio rerio) fatty acid beta-oxidation [GO:0006635] GO:0003985; GO:0005739; GO:0006635; GO:0046872 48845 XM_029334535.2 490 305 370 290 497 P43446 2.17e-91 Protein Wnt-10a Danio rerio (Zebrafish) (Brachydanio rerio) canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; neuron differentiation [GO:0030182]; odontogenesis [GO:0042476] GO:0005109; GO:0005125; GO:0005615; GO:0030182; GO:0042476; GO:0045165; GO:0060070 48846 XM_044307001.1 0 0 0 8 0 NA NA NA NA NA NA 48847 XM_029348053.2 597 641 515 327 419 Q0IJ33 9.34e-147 E3 ubiquitin-protein ligase TM129 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TM129) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) response to unfolded protein [GO:0006986] GO:0005789; GO:0006986; GO:0046872; GO:0061630 48848 XM_044309499.1 50 0 29 39 47 A3KN83 3.62e-102 Protein strawberry notch homolog 1 (Monocyte protein 3) (MOP-3) Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355]; regulation of response to stimulus [GO:0048583] GO:0005634; GO:0006355; GO:0031490; GO:0042393; GO:0048583 48849 XM_029335456.2 0 11 0 0 0 NA NA NA NA NA NA 48850 XR_006393123.1 95 989 207 764 587 NA NA NA NA NA NA 48851 XM_029324330.2 1509 717 171 1116 1670 B3EWZ9 0 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 48852 XM_029324330.2 1509 717 171 1116 1670 B3EWZ9 0 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 48853 XM_029327770.2 3 0 4 3 10 NA NA NA NA NA NA 48854 XM_044322685.1 0 2 0 0 10 NA NA NA NA NA NA 48855 XM_044308071.1 8 0 0 6 4 NA NA NA NA NA NA 48856 XM_029348357.2 0 0 16 0 0 Q99741 1.63e-133 Cell division control protein 6 homolog (CDC6-related protein) (Cdc18-related protein) (HsCdc18) (p62(cdc6)) (HsCDC6) Homo sapiens (Human) cell division [GO:0051301]; cellular response to angiotensin [GO:1904385]; cellular response to vasopressin [GO:1904117]; DNA replication checkpoint signaling [GO:0000076]; DNA replication initiation [GO:0006270]; mitotic cell cycle [GO:0000278]; mitotic DNA replication checkpoint signaling [GO:0033314]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; positive regulation of chromosome segregation [GO:0051984]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytokinesis [GO:0032467]; positive regulation of fibroblast proliferation [GO:0048146]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; traversing start control point of mitotic cell cycle [GO:0007089] GO:0000076; GO:0000079; GO:0000166; GO:0000278; GO:0000922; GO:0003688; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006270; GO:0007089; GO:0008156; GO:0008285; GO:0019900; GO:0030071; GO:0032467; GO:0033314; GO:0045171; GO:0045737; GO:0048146; GO:0051233; GO:0051301; GO:0051984; GO:0072686; GO:1904117; GO:1904385 48857 XM_044313149.1 532 16 219 13 205 NA NA NA NA NA NA 48858 XM_044325978.1 0 0 5 25 15 NA NA NA NA NA NA 48859 XM_044324458.1 171 143 92 44 0 NA NA NA NA NA NA 48860 XR_006395062.1 42 18 19 38 62 NA NA NA NA NA NA 48861 XM_044311986.1 16 0 0 101 44 NA NA NA NA NA NA 48862 XM_044317639.1 0 1 11 5 0 NA NA NA NA NA NA 48863 XM_044314513.1 1 0 8 0 0 NA NA NA NA NA NA 48864 XM_029331463.2 8 2 4 3 7 Q9Y466 4.93e-118 Nuclear receptor subfamily 2 group E member 1 (Nuclear receptor TLX) (Protein tailless homolog) (Tll) (hTll) Homo sapiens (Human) aggressive behavior [GO:0002118]; amygdala development [GO:0021764]; anatomical structure development [GO:0048856]; angiogenesis [GO:0001525]; anterior commissure morphogenesis [GO:0021960]; apoptotic process [GO:0006915]; astrocyte cell migration [GO:0043615]; astrocyte differentiation [GO:0048708]; behavioral fear response [GO:0001662]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; cerebral cortex neuron differentiation [GO:0021895]; dentate gyrus development [GO:0021542]; extracellular matrix organization [GO:0030198]; forebrain generation of neurons [GO:0021872]; layer formation in cerebral cortex [GO:0021819]; long-term synaptic potentiation [GO:0060291]; negative regulation of apoptotic process [GO:0043066]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of neural precursor cell proliferation [GO:2000178]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; neuroblast proliferation [GO:0007405]; olfactory bulb development [GO:0021772]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell cycle [GO:0045787]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of stem cell proliferation [GO:2000648]; regulation of cell migration involved in sprouting angiogenesis [GO:0090049]; regulation of dendrite morphogenesis [GO:0048814]; regulation of timing of neuron differentiation [GO:0060164]; regulation of transcription by RNA polymerase II [GO:0006357]; retina development in camera-type eye [GO:0060041]; social behavior [GO:0035176]; somatic stem cell population maintenance [GO:0035019]; visual perception [GO:0007601] GO:0000122; GO:0000785; GO:0000978; GO:0000981; GO:0001227; GO:0001228; GO:0001525; GO:0001662; GO:0002052; GO:0002118; GO:0003707; GO:0004879; GO:0005654; GO:0006357; GO:0006915; GO:0007399; GO:0007405; GO:0007601; GO:0008270; GO:0021542; GO:0021764; GO:0021772; GO:0021819; GO:0021872; GO:0021895; GO:0021960; GO:0030154; GO:0030198; GO:0035019; GO:0035176; GO:0042826; GO:0043066; GO:0043615; GO:0045165; GO:0045665; GO:0045766; GO:0045787; GO:0048708; GO:0048712; GO:0048814; GO:0048856; GO:0060041; GO:0060164; GO:0060291; GO:0090049; GO:1990837; GO:2000178; GO:2000648 48865 XM_029345376.2 1091 714 962 1130 1473 O96790 7.6e-25 Serine protease inhibitor dipetalogastin (Dipetalin) Dipetalogaster maximus (Blood-sucking bug) negative regulation of coagulation [GO:0050819]; negative regulation of peptidase activity [GO:0010466] GO:0004867; GO:0005576; GO:0010466; GO:0050819 48866 XM_044313643.1 153 16 15 187 114 NA NA NA NA NA NA 48867 XM_029328176.2 5 4 8 28 87 NA NA NA NA NA NA 48868 XM_029340122.2 226 144 86 129 137 NA NA NA NA NA NA 48869 XR_006394677.1 402 294 446 506 248 NA NA NA NA NA NA 48870 XM_029346155.2 45 20 86 47 0 Q9EPI9 0 Potassium voltage-gated channel subfamily H member 5 (Ether-a-go-go potassium channel 2) (rEAG2) (Voltage-gated potassium channel subunit Kv10.2) Rattus norvegicus (Rat) potassium ion transmembrane transport [GO:0071805]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391] GO:0005249; GO:0005516; GO:0005886; GO:0009986; GO:0010389; GO:0034765; GO:0042391; GO:0044325; GO:0044877; GO:0071805 48871 XM_044324704.1 0 0 28 47 16 NA NA NA NA NA NA 48872 XM_044317395.1 43 148 60 11 57 NA NA NA NA NA NA 48873 XM_029345671.2 157 0 92 1260 1278 Q8K0Q5 2.25e-95 Rho GTPase-activating protein 18 (Rho-type GTPase-activating protein 18) Mus musculus (Mouse) regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin filament polymerization [GO:0030833]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of small GTPase mediated signal transduction [GO:0051056]; small GTPase mediated signal transduction [GO:0007264] GO:0001726; GO:0005096; GO:0005737; GO:0005829; GO:0005881; GO:0005886; GO:0007264; GO:0008360; GO:0016607; GO:0030833; GO:0032956; GO:0051056; GO:2000145 48874 XM_029340571.2 20 0 8 20 60 NA NA NA NA NA NA 48875 XR_006397011.1 7 0 3 0 9 NA NA NA NA NA NA 48876 XR_006393052.1 117 20 42 155 75 NA NA NA NA NA NA 48877 XM_029349088.2 1459 1323 432 1081 1495 Q5U4F0 2.35e-76 Ribosomal RNA-processing protein 8 (EC 2.1.1.-) (Cerebral protein 1 homolog) Rattus norvegicus (Rat) cellular response to glucose starvation [GO:0042149]; energy homeostasis [GO:0097009]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; methylation [GO:0032259]; negative regulation of cell cycle [GO:0045786]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of histone methylation [GO:0031062]; rDNA heterochromatin formation [GO:0000183]; regulation of G1 to G0 transition [GO:1903450]; regulation of transcription by glucose [GO:0046015]; rRNA processing [GO:0006364] GO:0000183; GO:0005654; GO:0005677; GO:0005730; GO:0005829; GO:0005886; GO:0006364; GO:0008168; GO:0031062; GO:0031065; GO:0032259; GO:0033553; GO:0035064; GO:0042149; GO:0045786; GO:0045892; GO:0046015; GO:0061773; GO:0072332; GO:0097009; GO:1903450 48878 XM_044318848.1 363 363 182 381 603 NA NA NA NA NA NA 48879 XM_029351470.2 366 606 549 256 320 Q92506 5.6e-90 (3R)-3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.n12) (17-beta-hydroxysteroid dehydrogenase 8) (17-beta-HSD 8) (HSD17B8) (3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit) (KAR alpha subunit) (3-oxoacyl-[acyl-carrier-protein] reductase) (Estradiol 17-beta-dehydrogenase 8) (EC 1.1.1.62) (Protein Ke6) (Ke6) (Short chain dehydrogenase/reductase family 30C member 1) (Testosterone 17-beta-dehydrogenase 8) (EC 1.1.1.239) Homo sapiens (Human) androgen metabolic process [GO:0008209]; estrogen biosynthetic process [GO:0006703]; fatty acid biosynthetic process [GO:0006633]; protein heterotetramerization [GO:0051290] GO:0004303; GO:0005740; GO:0005759; GO:0005886; GO:0006633; GO:0006703; GO:0008209; GO:0016616; GO:0044594; GO:0047035; GO:0048038; GO:0051290; GO:0070404; GO:0106386; GO:1990204 48880 XM_029347865.2 0 0 0 35 0 NA NA NA NA NA NA 48881 XM_029340493.2 115 43 26 76 85 NA NA NA NA NA NA 48882 XM_044328808.1 0 4 0 0 9 NA NA NA NA NA NA 48883 XM_029343748.2 212 135 56 236 67 NA NA NA NA NA NA 48884 XM_044313113.1 463 338 239 357 323 NA NA NA NA NA NA 48885 XM_029337632.2 737 1770 1368 604 396 NA NA NA NA NA NA 48886 XR_003824109.2 330 277 245 239 208 NA NA NA NA NA NA 48887 XM_029331429.2 348 113 254 203 23 Q91V01 8.92e-92 Lysophospholipid acyltransferase 5 (LPLAT 5) (EC 2.3.1.-) (1-acylglycerophosphocholine O-acyltransferase) (EC 2.3.1.23) (1-acylglycerophosphoethanolamine O-acyltransferase) (EC 2.3.1.n7) (1-acylglycerophosphoserine O-acyltransferase) (EC 2.3.1.n6) (Lysophosphatidylcholine acyltransferase) (LPCAT) (Lyso-PC acyltransferase) (Lysophosphatidylcholine acyltransferase 3) (Lyso-PC acyltransferase 3) (mLPCAT3) (Lysophosphatidylethanolamine acyltransferase) (LPEAT) (Lyso-PE acyltransferase) (Lysophosphatidylserine acyltransferase) (LPSAT) (Lyso-PS acyltransferase) (Membrane-bound O-acyltransferase domain-containing protein 5) (O-acyltransferase domain-containing protein 5) Mus musculus (Mouse) chylomicron assembly [GO:0034378]; endoplasmic reticulum membrane organization [GO:0090158]; intestinal stem cell homeostasis [GO:0036335]; lipid modification [GO:0030258]; negative regulation of inflammatory response [GO:0050728]; negative regulation of response to endoplasmic reticulum stress [GO:1903573]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylcholine biosynthetic process [GO:0006656]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; phosphatidylserine acyl-chain remodeling [GO:0036150]; positive regulation of intestinal cholesterol absorption [GO:0045797]; positive regulation of sterol regulatory element binding protein cleavage [GO:1901310]; positive regulation of triglyceride transport [GO:1905885]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of plasma lipoprotein particle levels [GO:0097006]; very-low-density lipoprotein particle assembly [GO:0034379] GO:0005789; GO:0006656; GO:0016020; GO:0016746; GO:0030258; GO:0034378; GO:0034379; GO:0036150; GO:0036151; GO:0036152; GO:0036335; GO:0045540; GO:0045797; GO:0047184; GO:0050728; GO:0071617; GO:0090158; GO:0097006; GO:0106262; GO:0106263; GO:1901310; GO:1903573; GO:1905885 48888 XM_029338593.2 2165 2160 1571 1880 1221 NA NA NA NA NA NA 48889 XM_044310776.1 93 506 66 55 428 NA NA NA NA NA NA 48890 XM_029348726.2 446 334 146 332 204 Q5U508 5.17e-128 Tubulin-specific chaperone E (Tubulin-folding cofactor E) Xenopus laevis (African clawed frog) post-chaperonin tubulin folding pathway [GO:0007023] GO:0005737; GO:0005856; GO:0007023; GO:0043014 48891 XM_029341515.2 1174 1707 0 811 506 Q02974 2.5e-98 Ketohexokinase (EC 2.7.1.3) (Hepatic fructokinase) Rattus norvegicus (Rat) carbohydrate catabolic process [GO:0016052]; carbohydrate phosphorylation [GO:0046835]; fructose catabolic process [GO:0006001]; fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; fructose metabolic process [GO:0006000]; regulation of glycogen metabolic process [GO:0070873]; response to fructose [GO:0009750]; response to glucose [GO:0009749]; response to insulin [GO:0032868]; response to sucrose [GO:0009744]; response to zinc ion [GO:0010043] GO:0004454; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006000; GO:0006001; GO:0009744; GO:0009749; GO:0009750; GO:0010043; GO:0016052; GO:0032868; GO:0046835; GO:0061624; GO:0070873 48892 XR_006392867.1 192 110 3 0 15 NA NA NA NA NA NA 48893 XM_029347193.2 0 19 8 3 0 NA NA NA NA NA NA 48894 XR_006391734.1 821 778 477 1077 1121 P28047 1.25e-60 Protein Wnt-7b Mus musculus (Mouse) anatomical structure regression [GO:0060033]; angiogenesis [GO:0001525]; apoptotic process involved in blood vessel morphogenesis [GO:1902262]; canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; cell population proliferation [GO:0008283]; cell proliferation in forebrain [GO:0021846]; cellular oxygen homeostasis [GO:0032364]; central nervous system vasculogenesis [GO:0022009]; chemoattraction of dopaminergic neuron axon [GO:0036516]; chorio-allantoic fusion [GO:0060710]; developmental growth involved in morphogenesis [GO:0060560]; embryonic organ development [GO:0048568]; embryonic placenta morphogenesis [GO:0060669]; establishment or maintenance of polarity of embryonic epithelium [GO:0016332]; forebrain regionalization [GO:0021871]; homeostatic process [GO:0042592]; in utero embryonic development [GO:0001701]; inner medullary collecting duct development [GO:0072061]; lobar bronchus development [GO:0060482]; lung development [GO:0030324]; lung epithelium development [GO:0060428]; lung morphogenesis [GO:0060425]; lung-associated mesenchyme development [GO:0060484]; metanephric collecting duct development [GO:0072205]; metanephric epithelium development [GO:0072207]; metanephric loop of Henle development [GO:0072236]; metanephros morphogenesis [GO:0003338]; negative regulation of neurogenesis [GO:0050768]; negative regulation of smoothened signaling pathway [GO:0045879]; neuron differentiation [GO:0030182]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; odontogenesis of dentin-containing tooth [GO:0042475]; osteoblast differentiation [GO:0001649]; outer medullary collecting duct development [GO:0072060]; planar cell polarity pathway involved in axon guidance [GO:1904938]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of JNK cascade [GO:0046330]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell projection size [GO:0032536]; renal inner medulla development [GO:0072053]; renal outer medulla development [GO:0072054]; smooth muscle cell differentiation [GO:0051145]; stem cell development [GO:0048864]; synapse organization [GO:0050808]; trachea cartilage morphogenesis [GO:0060535]; vasculature development [GO:0001944]; Wnt signaling pathway [GO:0016055] GO:0001525; GO:0001649; GO:0001701; GO:0001944; GO:0003338; GO:0005109; GO:0005125; GO:0005615; GO:0005737; GO:0005788; GO:0005886; GO:0008283; GO:0008284; GO:0009986; GO:0010628; GO:0016055; GO:0016332; GO:0021846; GO:0021871; GO:0022009; GO:0030182; GO:0030324; GO:0031175; GO:0032364; GO:0032536; GO:0036516; GO:0042475; GO:0042592; GO:0045165; GO:0045669; GO:0045879; GO:0046330; GO:0048018; GO:0048568; GO:0048812; GO:0048864; GO:0050768; GO:0050808; GO:0051145; GO:0060033; GO:0060070; GO:0060425; GO:0060428; GO:0060482; GO:0060484; GO:0060535; GO:0060560; GO:0060669; GO:0060710; GO:0072053; GO:0072054; GO:0072060; GO:0072061; GO:0072205; GO:0072207; GO:0072236; GO:1902262; GO:1902379; GO:1904938 48895 XR_006391734.1 821 778 477 1077 1121 P28047 1.25e-60 Protein Wnt-7b Mus musculus (Mouse) anatomical structure regression [GO:0060033]; angiogenesis [GO:0001525]; apoptotic process involved in blood vessel morphogenesis [GO:1902262]; canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; cell population proliferation [GO:0008283]; cell proliferation in forebrain [GO:0021846]; cellular oxygen homeostasis [GO:0032364]; central nervous system vasculogenesis [GO:0022009]; chemoattraction of dopaminergic neuron axon [GO:0036516]; chorio-allantoic fusion [GO:0060710]; developmental growth involved in morphogenesis [GO:0060560]; embryonic organ development [GO:0048568]; embryonic placenta morphogenesis [GO:0060669]; establishment or maintenance of polarity of embryonic epithelium [GO:0016332]; forebrain regionalization [GO:0021871]; homeostatic process [GO:0042592]; in utero embryonic development [GO:0001701]; inner medullary collecting duct development [GO:0072061]; lobar bronchus development [GO:0060482]; lung development [GO:0030324]; lung epithelium development [GO:0060428]; lung morphogenesis [GO:0060425]; lung-associated mesenchyme development [GO:0060484]; metanephric collecting duct development [GO:0072205]; metanephric epithelium development [GO:0072207]; metanephric loop of Henle development [GO:0072236]; metanephros morphogenesis [GO:0003338]; negative regulation of neurogenesis [GO:0050768]; negative regulation of smoothened signaling pathway [GO:0045879]; neuron differentiation [GO:0030182]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; odontogenesis of dentin-containing tooth [GO:0042475]; osteoblast differentiation [GO:0001649]; outer medullary collecting duct development [GO:0072060]; planar cell polarity pathway involved in axon guidance [GO:1904938]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of JNK cascade [GO:0046330]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell projection size [GO:0032536]; renal inner medulla development [GO:0072053]; renal outer medulla development [GO:0072054]; smooth muscle cell differentiation [GO:0051145]; stem cell development [GO:0048864]; synapse organization [GO:0050808]; trachea cartilage morphogenesis [GO:0060535]; vasculature development [GO:0001944]; Wnt signaling pathway [GO:0016055] GO:0001525; GO:0001649; GO:0001701; GO:0001944; GO:0003338; GO:0005109; GO:0005125; GO:0005615; GO:0005737; GO:0005788; GO:0005886; GO:0008283; GO:0008284; GO:0009986; GO:0010628; GO:0016055; GO:0016332; GO:0021846; GO:0021871; GO:0022009; GO:0030182; GO:0030324; GO:0031175; GO:0032364; GO:0032536; GO:0036516; GO:0042475; GO:0042592; GO:0045165; GO:0045669; GO:0045879; GO:0046330; GO:0048018; GO:0048568; GO:0048812; GO:0048864; GO:0050768; GO:0050808; GO:0051145; GO:0060033; GO:0060070; GO:0060425; GO:0060428; GO:0060482; GO:0060484; GO:0060535; GO:0060560; GO:0060669; GO:0060710; GO:0072053; GO:0072054; GO:0072060; GO:0072061; GO:0072205; GO:0072207; GO:0072236; GO:1902262; GO:1902379; GO:1904938 48896 XM_044328957.1 0 0 0 0 46 Q9I8C7 3.11e-74 Neuronal acetylcholine receptor subunit alpha-10 (Alpha 10 nAChR) (Nicotinic acetylcholine receptor subunit alpha-10) (NACHR alpha-10) Gallus gallus (Chicken) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; response to auditory stimulus [GO:0010996]; signal transduction [GO:0007165] GO:0004888; GO:0005231; GO:0005262; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0010996; GO:0022848; GO:0030594; GO:0034220; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051899; GO:1904315 48897 XM_044313673.1 349 133 90 344 156 Q8TD19 1.51e-145 Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (Nercc1 kinase) (Never in mitosis A-related kinase 9) (NimA-related protein kinase 9) (NimA-related kinase 8) (Nek8) Homo sapiens (Human) cell division [GO:0051301]; mitotic cell cycle [GO:0000278]; protein phosphorylation [GO:0006468] GO:0000278; GO:0004674; GO:0005524; GO:0005634; GO:0005829; GO:0006468; GO:0019901; GO:0030295; GO:0046872; GO:0051301; GO:0106310 48898 XM_029344034.2 1859 1513 1095 626 1484 Q8BGH2 7.2e-140 Sorting and assembly machinery component 50 homolog Mus musculus (Mouse) cristae formation [GO:0042407]; mitochondrial respiratory chain complex assembly [GO:0033108]; protein insertion into mitochondrial outer membrane [GO:0045040] GO:0001401; GO:0005739; GO:0005741; GO:0005743; GO:0016020; GO:0033108; GO:0042407; GO:0045040 48899 XM_029351156.2 356 168 67 200 140 NA NA NA NA NA NA 48900 XM_044317271.1 689 569 481 710 607 Q8IY21 0 Probable ATP-dependent RNA helicase DDX60 (EC 3.6.4.13) (DEAD box protein 60) Homo sapiens (Human) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; response to virus [GO:0009615] GO:0003690; GO:0003724; GO:0003725; GO:0003727; GO:0005524; GO:0005737; GO:0005829; GO:0009615; GO:0016887; GO:0045087; GO:0045111; GO:0051607; GO:1900245; GO:1900246 48901 XM_029341205.2 1212 1523 1157 2171 3058 NA NA NA NA NA NA 48902 XR_003825376.2 1277 32697 606 1905 15783 NA NA NA NA NA NA 48903 XM_044327563.1 201 214 46 121 188 NA NA NA NA NA NA 48904 XM_044322555.1 9487 6628 7621 9910 10355 B9U3F2 2.33e-85 Protein dispatched homolog 3 (Patched domain-containing protein 2) (Thyroid hormone receptor up-regulated protein 1) (TRUP1) Gallus gallus (Chicken) cell differentiation [GO:0030154]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of neural precursor cell proliferation [GO:2000179]; response to hormone [GO:0009725] GO:0005737; GO:0005783; GO:0005789; GO:0008203; GO:0009725; GO:0016020; GO:0030154; GO:0030659; GO:0031965; GO:0042632; GO:0045665; GO:0045834; GO:2000179 48905 XM_044322555.1 9487 6628 7621 9910 10355 B9U3F2 3.36e-65 Protein dispatched homolog 3 (Patched domain-containing protein 2) (Thyroid hormone receptor up-regulated protein 1) (TRUP1) Gallus gallus (Chicken) cell differentiation [GO:0030154]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of neural precursor cell proliferation [GO:2000179]; response to hormone [GO:0009725] GO:0005737; GO:0005783; GO:0005789; GO:0008203; GO:0009725; GO:0016020; GO:0030154; GO:0030659; GO:0031965; GO:0042632; GO:0045665; GO:0045834; GO:2000179 48906 XR_006391954.1 9 0 31 0 8 NA NA NA NA NA NA 48907 XM_044307795.1 17 0 0 6 69 NA NA NA NA NA NA 48908 XM_044324511.1 0 1 19 0 108 NA NA NA NA NA NA 48909 XM_029329951.2 0 84 195 0 0 Q16445 4.68e-58 Gamma-aminobutyric acid receptor subunit alpha-6 (GABA(A) receptor subunit alpha-6) Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid signaling pathway [GO:0007214]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; regulation of postsynaptic membrane potential [GO:0060078]; signal transduction [GO:0007165]; synaptic transmission, GABAergic [GO:0051932] GO:0004890; GO:0005231; GO:0005237; GO:0005886; GO:0007165; GO:0007214; GO:0007268; GO:0008503; GO:0022851; GO:0030594; GO:0032590; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051932; GO:0060078; GO:0098794; GO:0099192; GO:1902476; GO:1902711; GO:1904315 48910 XR_006396561.1 437 1 217 7 1 NA NA NA NA NA NA 48911 XM_029348188.2 14547 17124 14650 19015 7118 Q9CQ19 2.55e-74 Myosin regulatory light polypeptide 9 (Myosin regulatory light chain 2, smooth muscle isoform) (Myosin regulatory light chain 9) Mus musculus (Mouse) myofibril assembly [GO:0030239] GO:0001725; GO:0005509; GO:0005737; GO:0005938; GO:0016460; GO:0030016; GO:0030018; GO:0030239; GO:0032036 48912 XM_029344226.2 31 7 30 7 102 NA NA NA NA NA NA 48913 XM_029340311.2 0 0 32 0 0 P35610 3.09e-138 Sterol O-acyltransferase 1 (EC 2.3.1.26) (Acyl-coenzyme A:cholesterol acyltransferase 1) (ACAT-1) (Cholesterol acyltransferase 1) Homo sapiens (Human) cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; cholesterol storage [GO:0010878]; low-density lipoprotein particle clearance [GO:0034383]; macrophage derived foam cell differentiation [GO:0010742]; positive regulation of amyloid precursor protein biosynthetic process [GO:0042986]; very-low-density lipoprotein particle assembly [GO:0034379] GO:0000062; GO:0004772; GO:0005783; GO:0005789; GO:0008203; GO:0008374; GO:0010742; GO:0010878; GO:0015485; GO:0016020; GO:0033344; GO:0034379; GO:0034383; GO:0034736; GO:0042632; GO:0042802; GO:0042986 48914 XM_029343441.2 35 3 34 17 191 NA NA NA NA NA NA 48915 XM_029334357.2 158 159 76 186 175 Q96GS4 1.66e-29 BLOC-1-related complex subunit 6 (Lysosome-dispersing protein) (Lyspersin) Homo sapiens (Human) lysosome localization [GO:0032418]; organelle transport along microtubule [GO:0072384]; regulation of endosome size [GO:0051036]; regulation of lysosome size [GO:0062196] GO:0032418; GO:0042802; GO:0051036; GO:0062196; GO:0072384; GO:0098574; GO:0099078 48916 XM_029343772.2 377 244 204 358 215 NA NA NA NA NA NA 48917 XM_029338389.2 164 88 131 157 99 Q05B89 1.82e-112 NIF3-like protein 1 Bos taurus (Bovine) negative regulation of nucleic acid-templated transcription [GO:1903507]; neuron differentiation [GO:0030182] GO:0005634; GO:0005737; GO:0005739; GO:0030182; GO:1903507 48918 XM_029329026.2 4277 3273 2995 3515 2988 Q96GG9 2.87e-128 DCN1-like protein 1 (DCNL1) (DCUN1 domain-containing protein 1) (Defective in cullin neddylation protein 1-like protein 1) (Squamous cell carcinoma-related oncogene) Homo sapiens (Human) positive regulation of protein neddylation [GO:2000436]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein neddylation [GO:0045116]; regulation of protein neddylation [GO:2000434]; regulation of protein ubiquitination [GO:0031396] GO:0000151; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0031396; GO:0031624; GO:0032182; GO:0045116; GO:0051443; GO:0097602; GO:2000434; GO:2000436 48919 XM_044306768.1 487 311 314 333 666 Q7RTR2 9.47e-56 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 48920 XM_044306768.1 487 311 314 333 666 Q7RTR2 9.17e-55 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 48921 XM_044306768.1 487 311 314 333 666 Q7RTR2 1.92e-54 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 48922 XM_044306768.1 487 311 314 333 666 Q7RTR2 1.23e-47 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 48923 XM_044306768.1 487 311 314 333 666 Q7RTR2 1.37e-31 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 48924 XR_006391572.1 1286 1333 731 864 742 NA NA NA NA NA NA 48925 XR_003828315.2 1085 1359 966 1517 1744 NA NA NA NA NA NA 48926 XM_029356311.2 3250 2120 1386 1849 1405 NA NA NA NA NA NA 48927 XM_044308313.1 552 409 510 810 895 Q9R101 1.31e-129 Hormone-sensitive lipase (HSL) (EC 3.1.1.79) (Monoacylglycerol lipase LIPE) (EC 3.1.1.23) (Retinyl ester hydrolase) (REH) Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus tridecemlineatus) cholesterol metabolic process [GO:0008203]; diacylglycerol catabolic process [GO:0046340]; ether lipid metabolic process [GO:0046485]; lipid catabolic process [GO:0016042]; termination of RNA polymerase I transcription [GO:0006363]; transcription initiation at RNA polymerase I promoter [GO:0006361]; triglyceride catabolic process [GO:0019433] GO:0004771; GO:0004806; GO:0005634; GO:0005737; GO:0005739; GO:0005811; GO:0005829; GO:0005901; GO:0006361; GO:0006363; GO:0008203; GO:0016020; GO:0016042; GO:0019433; GO:0033878; GO:0042134; GO:0046340; GO:0046485; GO:0047372; GO:0047376; GO:0050253; GO:0102258; GO:0102259 48928 XM_029344104.2 32 24 37 8 41 Q9BX70 9.42e-54 BTB/POZ domain-containing protein 2 Homo sapiens (Human) neurogenesis [GO:0022008] GO:0000932; GO:0005829; GO:0022008 48929 XM_044309031.1 44 37 29 83 30 NA NA NA NA NA NA 48930 XM_044316483.1 456 88 15 584 557 NA NA NA NA NA NA 48931 XM_029338046.2 1558 889 905 1451 1220 Q92738 5.35e-140 USP6 N-terminal-like protein (Related to the N-terminus of tre) (RN-tre) Homo sapiens (Human) activation of GTPase activity [GO:0090630]; Golgi organization [GO:0007030]; plasma membrane to endosome transport [GO:0048227]; positive regulation of GTPase activity [GO:0043547]; regulation of Golgi organization [GO:1903358]; retrograde transport, plasma membrane to Golgi [GO:0035526]; virion assembly [GO:0019068] GO:0005096; GO:0005829; GO:0005886; GO:0007030; GO:0019068; GO:0031267; GO:0031410; GO:0032588; GO:0035526; GO:0043547; GO:0048227; GO:0090630; GO:1903358 48932 XM_044319087.1 12 96 2 8 23 Q9QZ85 1.27e-51 Interferon-inducible GTPase 1 (EC 3.6.5.-) Mus musculus (Mouse) cellular response to interferon-beta [GO:0035458]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; regulation of autophagy [GO:0010506]; response to bacterium [GO:0009617] GO:0003924; GO:0005525; GO:0005737; GO:0005789; GO:0006952; GO:0009617; GO:0010506; GO:0019003; GO:0019221; GO:0020005; GO:0031965; GO:0032580; GO:0035458; GO:0042802; GO:0042832; GO:0045087; GO:0050829 48933 XR_006398002.1 53 30 2 77 3 NA NA NA NA NA NA 48934 XR_003824796.2 13 42 13 20 21 NA NA NA NA NA NA 48935 XM_029358180.2 0 5 25 0 42 E9PZZ1 5.56e-26 PR domain zinc finger protein 13 (EC 2.1.1.-) (PR domain-containing protein 13) Mus musculus (Mouse) GABAergic neuron differentiation [GO:0097154]; hypothalamus cell differentiation [GO:0021979]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of gene expression [GO:0010468] GO:0000122; GO:0003677; GO:0003682; GO:0005634; GO:0010468; GO:0021979; GO:0022008; GO:0042054; GO:0046872; GO:0061629; GO:0097154 48936 XM_044317330.1 14 489 5 17 2 NA NA NA NA NA NA 48937 XM_029345109.2 45 0 5 42 61 Q9DBW0 2.75e-142 Cytochrome P450 4V2 (Docosahexaenoic acid omega-hydroxylase CYP4V2) (EC 1.14.14.79) (Long-chain fatty acid omega-monooxygenase) (EC 1.14.14.80) Mus musculus (Mouse) fatty acid omega-oxidation [GO:0010430] GO:0005506; GO:0005789; GO:0010430; GO:0020037; GO:0102033 48938 XM_029338356.2 200 0 64 0 4 Q9FL28 8.39e-23 LRR receptor-like serine/threonine-protein kinase FLS2 (EC 2.7.11.1) (Protein FLAGELLIN-SENSING 2) (Protein FLAGELLIN-SENSITIVE 2) Arabidopsis thaliana (Mouse-ear cress) defense response by callose deposition in cell wall [GO:0052544]; defense response to bacterium [GO:0042742]; detection of bacterium [GO:0016045]; protein phosphorylation [GO:0006468]; receptor-mediated endocytosis [GO:0006898]; regulation of anion channel activity [GO:0010359] GO:0004675; GO:0005524; GO:0005768; GO:0005886; GO:0006468; GO:0006898; GO:0010008; GO:0010359; GO:0012505; GO:0016020; GO:0016045; GO:0042742; GO:0042802; GO:0052544; GO:0106310 48939 XM_029332924.2 35 81 23 82 114 P93208 3.2e-87 14-3-3 protein 2 Solanum lycopersicum (Tomato) (Lycopersicon esculentum) signal transduction [GO:0007165] GO:0005737; GO:0007165 48940 XM_029358590.2 910 466 734 407 752 O75191 0 Xylulose kinase (Xylulokinase) (EC 2.7.1.17) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; D-xylose metabolic process [GO:0042732]; generation of precursor metabolites and energy [GO:0006091]; glucuronate catabolic process to xylulose 5-phosphate [GO:0019640]; phosphorylation [GO:0016310]; xylulose catabolic process [GO:0005998]; xylulose metabolic process [GO:0005997] GO:0004856; GO:0005524; GO:0005829; GO:0005975; GO:0005997; GO:0005998; GO:0006091; GO:0016310; GO:0016773; GO:0019640; GO:0042732 48941 XM_029352447.2 225 13 8 642 138 NA NA NA NA NA NA 48942 XM_029340552.2 1854 1530 1145 1621 1863 P36514 2.22e-88 UDP-glucuronosyltransferase 2C1 (UDPGT 2C1) (EC 2.4.1.17) Oryctolagus cuniculus (Rabbit) lipid metabolic process [GO:0006629] GO:0005789; GO:0006629; GO:0015020 48943 XM_044324293.1 418 130 181 776 1133 P60882 0 Multiple epidermal growth factor-like domains protein 8 (Multiple EGF-like domains protein 8) (Epidermal growth factor-like protein 4) (EGF-like protein 4) Mus musculus (Mouse) animal organ morphogenesis [GO:0009887]; BMP signaling pathway [GO:0030509]; cell migration involved in gastrulation [GO:0042074]; coronary vasculature development [GO:0060976]; craniofacial suture morphogenesis [GO:0097094]; determination of digestive tract left/right asymmetry [GO:0071907]; determination of heart left/right asymmetry [GO:0061371]; determination of left/right symmetry [GO:0007368]; embryonic heart tube left/right pattern formation [GO:0060971]; embryonic heart tube morphogenesis [GO:0003143]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; epiboly involved in gastrulation with mouth forming second [GO:0055113]; fasciculation of sensory neuron axon [GO:0097155]; left/right pattern formation [GO:0060972]; limb morphogenesis [GO:0035108]; negative regulation of smoothened signaling pathway [GO:0045879]; positive regulation of axon extension involved in axon guidance [GO:0048842]; regulation of gene expression [GO:0010468]; tissue development [GO:0009888] GO:0003143; GO:0005509; GO:0005634; GO:0007368; GO:0009887; GO:0009888; GO:0010468; GO:0016020; GO:0030326; GO:0030509; GO:0035108; GO:0042074; GO:0045879; GO:0048704; GO:0048842; GO:0055113; GO:0060971; GO:0060972; GO:0060976; GO:0061371; GO:0071907; GO:0097094; GO:0097155 48944 XM_044324293.1 418 130 181 776 1133 P60882 2.47e-116 Multiple epidermal growth factor-like domains protein 8 (Multiple EGF-like domains protein 8) (Epidermal growth factor-like protein 4) (EGF-like protein 4) Mus musculus (Mouse) animal organ morphogenesis [GO:0009887]; BMP signaling pathway [GO:0030509]; cell migration involved in gastrulation [GO:0042074]; coronary vasculature development [GO:0060976]; craniofacial suture morphogenesis [GO:0097094]; determination of digestive tract left/right asymmetry [GO:0071907]; determination of heart left/right asymmetry [GO:0061371]; determination of left/right symmetry [GO:0007368]; embryonic heart tube left/right pattern formation [GO:0060971]; embryonic heart tube morphogenesis [GO:0003143]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; epiboly involved in gastrulation with mouth forming second [GO:0055113]; fasciculation of sensory neuron axon [GO:0097155]; left/right pattern formation [GO:0060972]; limb morphogenesis [GO:0035108]; negative regulation of smoothened signaling pathway [GO:0045879]; positive regulation of axon extension involved in axon guidance [GO:0048842]; regulation of gene expression [GO:0010468]; tissue development [GO:0009888] GO:0003143; GO:0005509; GO:0005634; GO:0007368; GO:0009887; GO:0009888; GO:0010468; GO:0016020; GO:0030326; GO:0030509; GO:0035108; GO:0042074; GO:0045879; GO:0048704; GO:0048842; GO:0055113; GO:0060971; GO:0060972; GO:0060976; GO:0061371; GO:0071907; GO:0097094; GO:0097155 48945 XM_044324293.1 418 130 181 776 1133 P60882 2.09e-38 Multiple epidermal growth factor-like domains protein 8 (Multiple EGF-like domains protein 8) (Epidermal growth factor-like protein 4) (EGF-like protein 4) Mus musculus (Mouse) animal organ morphogenesis [GO:0009887]; BMP signaling pathway [GO:0030509]; cell migration involved in gastrulation [GO:0042074]; coronary vasculature development [GO:0060976]; craniofacial suture morphogenesis [GO:0097094]; determination of digestive tract left/right asymmetry [GO:0071907]; determination of heart left/right asymmetry [GO:0061371]; determination of left/right symmetry [GO:0007368]; embryonic heart tube left/right pattern formation [GO:0060971]; embryonic heart tube morphogenesis [GO:0003143]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; epiboly involved in gastrulation with mouth forming second [GO:0055113]; fasciculation of sensory neuron axon [GO:0097155]; left/right pattern formation [GO:0060972]; limb morphogenesis [GO:0035108]; negative regulation of smoothened signaling pathway [GO:0045879]; positive regulation of axon extension involved in axon guidance [GO:0048842]; regulation of gene expression [GO:0010468]; tissue development [GO:0009888] GO:0003143; GO:0005509; GO:0005634; GO:0007368; GO:0009887; GO:0009888; GO:0010468; GO:0016020; GO:0030326; GO:0030509; GO:0035108; GO:0042074; GO:0045879; GO:0048704; GO:0048842; GO:0055113; GO:0060971; GO:0060972; GO:0060976; GO:0061371; GO:0071907; GO:0097094; GO:0097155 48946 XM_044324293.1 418 130 181 776 1133 P60882 6.15e-28 Multiple epidermal growth factor-like domains protein 8 (Multiple EGF-like domains protein 8) (Epidermal growth factor-like protein 4) (EGF-like protein 4) Mus musculus (Mouse) animal organ morphogenesis [GO:0009887]; BMP signaling pathway [GO:0030509]; cell migration involved in gastrulation [GO:0042074]; coronary vasculature development [GO:0060976]; craniofacial suture morphogenesis [GO:0097094]; determination of digestive tract left/right asymmetry [GO:0071907]; determination of heart left/right asymmetry [GO:0061371]; determination of left/right symmetry [GO:0007368]; embryonic heart tube left/right pattern formation [GO:0060971]; embryonic heart tube morphogenesis [GO:0003143]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; epiboly involved in gastrulation with mouth forming second [GO:0055113]; fasciculation of sensory neuron axon [GO:0097155]; left/right pattern formation [GO:0060972]; limb morphogenesis [GO:0035108]; negative regulation of smoothened signaling pathway [GO:0045879]; positive regulation of axon extension involved in axon guidance [GO:0048842]; regulation of gene expression [GO:0010468]; tissue development [GO:0009888] GO:0003143; GO:0005509; GO:0005634; GO:0007368; GO:0009887; GO:0009888; GO:0010468; GO:0016020; GO:0030326; GO:0030509; GO:0035108; GO:0042074; GO:0045879; GO:0048704; GO:0048842; GO:0055113; GO:0060971; GO:0060972; GO:0060976; GO:0061371; GO:0071907; GO:0097094; GO:0097155 48947 XM_029339247.2 0 68 0 0 183 NA NA NA NA NA NA 48948 XM_029353920.2 998 545 575 932 982 Q9Z1Z3 3.27e-94 Epsin-2 (EPS-15-interacting protein 2) Rattus norvegicus (Rat) embryonic organ development [GO:0048568]; endocytosis [GO:0006897]; in utero embryonic development [GO:0001701]; negative regulation of sprouting angiogenesis [GO:1903671]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; Notch signaling pathway [GO:0007219]; positive regulation of Notch signaling pathway [GO:0045747]; regulation of endocytosis [GO:0030100] GO:0001701; GO:0005543; GO:0005768; GO:0005886; GO:0006897; GO:0007219; GO:0030100; GO:0030125; GO:0030128; GO:0030276; GO:0030948; GO:0045747; GO:0048568; GO:1903671 48949 XR_006395261.1 253 130 113 419 423 Q9VC47 6.34e-35 NA NA NA NA 48950 XR_006395261.1 253 130 113 419 423 Q9VC47 6.34e-35 NA NA NA NA 48951 XM_029329663.2 2427 1357 983 1971 1335 Q99MD6 0 Thioredoxin reductase 3 (EC 1.8.1.9) (Thioredoxin and glutathione reductase) (Thioredoxin reductase TR2) Mus musculus (Mouse) blastocyst formation [GO:0001825]; cell differentiation [GO:0030154]; cell redox homeostasis [GO:0045454]; glutathione metabolic process [GO:0006749]; spermatogenesis [GO:0007283] GO:0001825; GO:0004791; GO:0005654; GO:0005739; GO:0005783; GO:0005829; GO:0006749; GO:0007283; GO:0030154; GO:0045454; GO:0050660 48952 XR_003826846.2 246 117 327 111 894 NA NA NA NA NA NA 48953 XM_029341592.2 60 47 44 74 83 NA NA NA NA NA NA 48954 XM_044322843.1 0 14 0 0 0 NA NA NA NA NA NA 48955 XM_044307332.1 34 9 14 47 30 Q7TN88 2.5e-55 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 48956 XM_044307332.1 34 9 14 47 30 Q7TN88 1.15e-23 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 48957 XM_029358074.2 2964 2894 2028 3079 3039 NA NA NA NA NA NA 48958 XM_044316016.1 0 0 0 38 0 NA NA NA NA NA NA 48959 XM_044315072.1 152 65 250 81 130 Q98TX3 1.61e-87 Programmed cell death protein 4 (Protein I11/6) Gallus gallus (Chicken) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of JUN kinase activity [GO:0043508] GO:0003723; GO:0005634; GO:0005737; GO:0005829; GO:0043508; GO:0045892 48960 XM_029335947.2 1 0 115 1 0 Q12767 2.01e-137 Transmembrane protein 94 Homo sapiens (Human) NA GO:0016020 48961 XM_029335947.2 1 0 115 1 0 Q12767 1.2e-32 Transmembrane protein 94 Homo sapiens (Human) NA GO:0016020 48962 XM_029333978.2 1574 1656 396 700 839 Q9WVL0 2.35e-94 Maleylacetoacetate isomerase (MAAI) (EC 5.2.1.2) (GSTZ1-1) (Glutathione S-transferase zeta 1) (EC 2.5.1.18) Mus musculus (Mouse) glutathione metabolic process [GO:0006749]; L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572] GO:0004364; GO:0005739; GO:0006559; GO:0006572; GO:0006749; GO:0016034; GO:0042802; GO:0042803 48963 XM_044326529.1 4909 3022 2733 4132 4279 NA NA NA NA NA NA 48964 XM_044328789.1 439 196 242 358 535 NA NA NA NA NA NA 48965 XM_029334351.2 36 78 98 203 0 E9PUQ8 0 Diacylglycerol kinase delta (DAG kinase delta) (EC 2.7.1.107) Mus musculus (Mouse) diacylglycerol metabolic process [GO:0046339]; endocytosis [GO:0006897]; intracellular signal transduction [GO:0035556]; lipid phosphorylation [GO:0046834]; negative regulation of protein kinase C signaling [GO:0090038]; phosphatidic acid biosynthetic process [GO:0006654]; positive regulation of clathrin-dependent endocytosis [GO:2000370]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; protein transport [GO:0015031]; response to organic substance [GO:0010033] GO:0004143; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0005905; GO:0006654; GO:0006897; GO:0007205; GO:0010033; GO:0015031; GO:0019900; GO:0031410; GO:0035556; GO:0042802; GO:0042803; GO:0045742; GO:0046339; GO:0046834; GO:0046872; GO:0046982; GO:0090038; GO:2000370 48966 XM_044310160.1 60 124 248 156 163 NA NA NA NA NA NA 48967 XM_029340259.2 364 109 200 182 348 Q9DBV3 0 Probable ATP-dependent RNA helicase DHX34 (EC 3.6.4.13) (DEAH box protein 34) (DExH-box helicase 34) Mus musculus (Mouse) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of phosphorylation [GO:0042327] GO:0000184; GO:0000956; GO:0003723; GO:0003724; GO:0005524; GO:0016887; GO:0042327; GO:0044877; GO:2000623 48968 XM_044323651.1 14 2 45 100 41 NA NA NA NA NA NA 48969 XR_006393881.1 31 0 0 122 41 NA NA NA NA NA NA 48970 XM_044320285.1 0 27 2 0 9 P26152 7.95e-57 Neuronal acetylcholine receptor subunit alpha-5 Gallus gallus (Chicken) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; response to nicotine [GO:0035094]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271] GO:0004888; GO:0005231; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0007271; GO:0022848; GO:0030594; GO:0034220; GO:0035094; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051899; GO:1904315 48971 XM_044328304.1 0 0 10 0 9 Q5XIR6 6.66e-24 Dynein regulatory complex protein 10 (IQ domain-containing protein D) Rattus norvegicus (Rat) NA GO:0005737; GO:0031514; GO:0036064 48972 XM_029331928.2 45 14 0 75 19 Q9BQS2 7.95e-35 Synaptotagmin-15 (Chr10Syt) (Synaptotagmin XV) (SytXV) Homo sapiens (Human) calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; vesicle-mediated transport [GO:0016192] GO:0000149; GO:0001786; GO:0005509; GO:0005544; GO:0005886; GO:0014059; GO:0016192; GO:0017156; GO:0017158; GO:0030276; GO:0070382; GO:0071277 48973 XM_029334042.2 551 98 210 63 419 Q00168 2.32e-59 Calcium/calmodulin-dependent protein kinase type II alpha chain (CaM-kinase II alpha chain) (EC 2.7.11.17) Drosophila melanogaster (Fruit fly) cellular response to starvation [GO:0009267]; chemical synaptic transmission [GO:0007268]; courtship behavior [GO:0007619]; learning or memory [GO:0007611]; long-term memory [GO:0007616]; male courtship behavior [GO:0008049]; negative regulation of cytokine production [GO:0001818]; negative regulation of lipid storage [GO:0010888]; neuromuscular junction development [GO:0007528]; peptidyl-threonine autophosphorylation [GO:1990443]; positive regulation of synaptic transmission, dopaminergic [GO:0032226]; protein phosphorylation [GO:0006468]; regulation of filopodium assembly [GO:0051489]; regulation of ovulation [GO:0060278]; regulation of synaptic assembly at neuromuscular junction [GO:0008582] GO:0001818; GO:0004674; GO:0004683; GO:0005516; GO:0005524; GO:0005737; GO:0006468; GO:0007268; GO:0007528; GO:0007611; GO:0007616; GO:0007619; GO:0008049; GO:0008582; GO:0009267; GO:0010888; GO:0030424; GO:0030425; GO:0032226; GO:0043005; GO:0045211; GO:0048786; GO:0051489; GO:0060278; GO:0106310; GO:1990443 48974 XM_029332269.2 2684 2336 1335 1765 2011 P56812 3e-34 Programmed cell death protein 5 (TF-1 cell apoptosis-related protein 19) (Protein TFAR19) Mus musculus (Mouse) apoptotic process [GO:0006915]; cellular response to transforming growth factor beta stimulus [GO:0071560]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chaperone-mediated protein folding [GO:1903645]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of gene expression [GO:0010628]; positive regulation of protein insertion into mitochondrial outer membrane [GO:1903638]; positive regulation of release of cytochrome c from mitochondria [GO:0090200] GO:0003677; GO:0005634; GO:0005737; GO:0005829; GO:0006915; GO:0008201; GO:0008285; GO:0010628; GO:0010698; GO:0043065; GO:0043280; GO:0048487; GO:0071560; GO:0090200; GO:1903638; GO:1903645 48975 XR_006392785.1 0 7 0 7 7 NA NA NA NA NA NA 48976 XM_044327567.1 247 20 170 644 0 Q6DKN2 9.43e-32 Homeobox protein OTX2-B (xOTX2-B) (Orthodenticle 2-B) (Orthodenticle-A-like protein B) Xenopus laevis (African clawed frog) NA GO:0000981; GO:0003677; GO:0005634 48977 XM_029358538.2 517 598 323 395 115 Q5ZL26 1.54e-145 Phosphoribosyl pyrophosphate synthase-associated protein 2 (PRPP synthase-associated protein 2) Gallus gallus (Chicken) 5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; purine nucleotide biosynthetic process [GO:0006164] GO:0000287; GO:0002189; GO:0004749; GO:0005737; GO:0006015; GO:0006164 48978 XM_044320916.1 12 4 2 23 19 Q9VBW3 9.85e-45 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 48979 XM_044311626.1 0 9 11 25 39 NA NA NA NA NA NA 48980 XM_044311624.1 0 2 0 29 0 NA NA NA NA NA NA 48981 XM_029350687.2 852 67 502 1390 214 NA NA NA NA NA NA 48982 XM_029355285.2 0 0 2 16 22 NA NA NA NA NA NA 48983 XM_044323717.1 5 0 9 0 8 NA NA NA NA NA NA 48984 XM_029357639.2 164 22 55 187 136 NA NA NA NA NA NA 48985 XR_006392390.1 1333 687 827 1010 998 Q5F364 0 Multidrug resistance-associated protein 1 (EC 7.6.2.2) (ATP-binding cassette sub-family C member 1) (Glutathione-S-conjugate-translocating ATPase ABCC1) (EC 7.6.2.3) (Leukotriene C(4) transporter) (LTC4 transporter) Gallus gallus (Chicken) glutathione transmembrane transport [GO:0034775]; lipid transport [GO:0006869]; transmembrane transport [GO:0055085]; xenobiotic transport [GO:0042908] GO:0005524; GO:0006869; GO:0008559; GO:0016020; GO:0016323; GO:0016887; GO:0034634; GO:0034775; GO:0042626; GO:0042908; GO:0055085 48986 XR_006395929.1 0 0 0 9 4 NA NA NA NA NA NA 48987 XR_003824686.2 512 493 155 326 482 NA NA NA NA NA NA 48988 XM_044316586.1 77 76 60 58 50 Q5FVR2 7.32e-117 Thymidine phosphorylase (TP) (EC 2.4.2.4) (TdRPase) Rattus norvegicus (Rat) dTMP catabolic process [GO:0046074]; mitochondrial genome maintenance [GO:0000002]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside metabolic process [GO:0006213]; regulation of gastric motility [GO:1905333]; regulation of myelination [GO:0031641]; regulation of transmission of nerve impulse [GO:0051969] GO:0000002; GO:0004645; GO:0005829; GO:0006206; GO:0006213; GO:0009032; GO:0016154; GO:0031641; GO:0042803; GO:0046074; GO:0051969; GO:1905333 48989 XM_044324891.1 428 217 201 511 468 Q8K4M9 0 Oxysterol-binding protein-related protein 1 (ORP-1) (OSBP-related protein 1) Rattus norvegicus (Rat) NA GO:0005768; GO:0005770; GO:0005829; GO:0015248; GO:0015485; GO:0016020; GO:0032934; GO:0043231; GO:0044232 48990 XM_029342782.2 29 40 41 34 22 NA NA NA NA NA NA 48991 XM_029346241.2 63 25 57 0 0 NA NA NA NA NA NA 48992 XM_044328105.1 202 144 219 32 125 NA NA NA NA NA NA 48993 XM_044308456.1 68 21 32 45 64 O75382 1.91e-27 Tripartite motif-containing protein 3 (Brain-expressed RING finger protein) (RING finger protein 22) (RING finger protein 97) Homo sapiens (Human) nervous system development [GO:0007399]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; protein transport [GO:0015031] GO:0000209; GO:0005737; GO:0005769; GO:0005794; GO:0007399; GO:0008022; GO:0008270; GO:0015031; GO:0030425; GO:0042802; GO:0043161; GO:0061630 48994 XM_044313759.1 269 30 261 47 667 NA NA NA NA NA NA 48995 XM_044318545.1 728 481 471 840 952 P35445 3.92e-134 Cartilage oligomeric matrix protein (COMP) Bos taurus (Bovine) apoptotic process [GO:0006915]; artery morphogenesis [GO:0048844]; BMP signaling pathway [GO:0030509]; bone mineralization [GO:0030282]; cartilage homeostasis [GO:1990079]; chondrocyte development [GO:0002063]; chondrocyte proliferation [GO:0035988]; collagen fibril organization [GO:0030199]; growth plate cartilage development [GO:0003417]; limb development [GO:0060173]; multicellular organism aging [GO:0010259]; multicellular organism growth [GO:0035264]; musculoskeletal movement [GO:0050881]; negative regulation of apoptotic process [GO:0043066]; negative regulation of hemostasis [GO:1900047]; platelet aggregation [GO:0070527]; positive regulation of chondrocyte proliferation [GO:1902732]; protein homooligomerization [GO:0051260]; protein processing [GO:0016485]; protein secretion [GO:0009306]; regulation of bone mineralization [GO:0030500]; regulation of gene expression [GO:0010468]; response to unfolded protein [GO:0006986]; skin development [GO:0043588]; tendon development [GO:0035989]; vascular associated smooth muscle cell development [GO:0097084]; vascular associated smooth muscle contraction [GO:0014829] GO:0002020; GO:0002063; GO:0003417; GO:0005178; GO:0005509; GO:0005518; GO:0005576; GO:0005615; GO:0006915; GO:0006986; GO:0008201; GO:0009306; GO:0010259; GO:0010468; GO:0014829; GO:0016485; GO:0030199; GO:0030282; GO:0030500; GO:0030509; GO:0032991; GO:0035264; GO:0035988; GO:0035989; GO:0036122; GO:0043066; GO:0043395; GO:0043588; GO:0048844; GO:0050881; GO:0051260; GO:0060173; GO:0062023; GO:0070527; GO:0097084; GO:1900047; GO:1902732; GO:1990079 48996 XM_029327492.2 49 69 87 52 20 Q1LUI2 1.49e-72 5'-deoxynucleotidase HDDC2 (EC 3.1.3.89) (HD domain-containing protein 2) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0002953; GO:0046872 48997 XR_003826042.2 407 180 1 490 51 NA NA NA NA NA NA 48998 XM_029333647.2 213 94 70 348 332 Q9UJA9 2.2e-67 Ectonucleotide pyrophosphatase/phosphodiesterase family member 5 (E-NPP 5) (NPP-5) (EC 3.1.-.-) Homo sapiens (Human) cell communication [GO:0007154] GO:0000210; GO:0005576; GO:0005886; GO:0007154; GO:0008270 48999 XM_029339923.2 4976 7255 3588 7753 5011 NA NA NA NA NA NA 49000 XM_029331047.2 387 198 119 345 360 Q3SZI7 0 Conserved oligomeric Golgi complex subunit 6 (COG complex subunit 6) (Component of oligomeric Golgi complex 6) Bos taurus (Bovine) glycosylation [GO:0070085]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein transport [GO:0015031] GO:0000139; GO:0006891; GO:0015031; GO:0017119; GO:0070085 49001 XM_029346058.2 1558 980 853 1852 1861 Q8CFK2 5.15e-148 Transcription factor IIIB 90 kDa subunit (TFIIIB90) (mTFIIIB90) (B-related factor 1) (BRF-1) Mus musculus (Mouse) DNA-templated transcription initiation [GO:0006352]; positive regulation of transcription by RNA polymerase III [GO:0045945]; regulation of mRNA stability [GO:0043488]; transcription by RNA polymerase III [GO:0006383]; transcription preinitiation complex assembly [GO:0070897] GO:0000126; GO:0000995; GO:0001006; GO:0005634; GO:0006352; GO:0006383; GO:0017025; GO:0043488; GO:0045945; GO:0046872; GO:0070897; GO:0097550 49002 XR_006394816.1 0 10 36 33 144 NA NA NA NA NA NA 49003 XM_044327425.1 25 8 116 0 0 P50130 5.91e-38 D(1A) dopamine receptor (Dopamine D1 receptor) Sus scrofa (Pig) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; vasodilation [GO:0042311] GO:0004930; GO:0004952; GO:0005789; GO:0005886; GO:0007189; GO:0042311; GO:0043197 49004 XM_029336444.2 995 1120 557 978 917 Q5ZHY5 1.72e-119 E3 ubiquitin-protein ligase CHIP (EC 2.3.2.27) (RING-type E3 ubiquitin transferase CHIP) (STIP1 homology and U box-containing protein 1) Gallus gallus (Chicken) cellular response to misfolded protein [GO:0071218]; DNA repair [GO:0006281]; positive regulation of proteolysis [GO:0045862]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000209; GO:0004842; GO:0005737; GO:0006281; GO:0006511; GO:0006515; GO:0030018; GO:0034450; GO:0042803; GO:0043161; GO:0045862; GO:0051087; GO:0061630; GO:0071218 49005 XR_003826450.2 21 7 6 39 54 NA NA NA NA NA NA 49006 XM_029355190.2 1 0 0 172 38 NA NA NA NA NA NA 49007 XM_044318976.1 312 421 228 218 370 P70196 5.98e-75 TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6) Mus musculus (Mouse) activation of NF-kappaB-inducing kinase activity [GO:0007250]; activation of protein kinase activity [GO:0032147]; animal organ morphogenesis [GO:0009887]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; bone remodeling [GO:0046849]; bone resorption [GO:0045453]; cell development [GO:0048468]; cellular response to cytokine stimulus [GO:0071345]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-17-mediated signaling pathway [GO:0097400]; JNK cascade [GO:0007254]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin production [GO:0002637]; response to interleukin-1 [GO:0070555]; signal transduction [GO:0007165]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000122; GO:0000209; GO:0001503; GO:0001701; GO:0001843; GO:0002637; GO:0002726; GO:0004842; GO:0005164; GO:0005634; GO:0005737; GO:0005811; GO:0005829; GO:0005886; GO:0005938; GO:0006955; GO:0006974; GO:0007165; GO:0007249; GO:0007250; GO:0007254; GO:0008270; GO:0009887; GO:0009898; GO:0016567; GO:0019221; GO:0019886; GO:0019901; GO:0030316; GO:0031435; GO:0031624; GO:0031625; GO:0031663; GO:0031666; GO:0031996; GO:0032147; GO:0032735; GO:0032743; GO:0032755; GO:0032813; GO:0032991; GO:0033209; GO:0035631; GO:0042088; GO:0042102; GO:0042475; GO:0042802; GO:0042826; GO:0042981; GO:0043011; GO:0043122; GO:0043123; GO:0043422; GO:0043507; GO:0045453; GO:0045672; GO:0045892; GO:0045944; GO:0046330; GO:0046849; GO:0047485; GO:0048468; GO:0048471; GO:0048661; GO:0050852; GO:0051091; GO:0051092; GO:0051865; GO:0061630; GO:0070498; GO:0070534; GO:0070555; GO:0071222; GO:0071345; GO:0097400; GO:1901224; GO:1904996; GO:2000679 49008 XM_044318976.1 312 421 228 218 370 P70196 5.98e-75 TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6) Mus musculus (Mouse) activation of NF-kappaB-inducing kinase activity [GO:0007250]; activation of protein kinase activity [GO:0032147]; animal organ morphogenesis [GO:0009887]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; bone remodeling [GO:0046849]; bone resorption [GO:0045453]; cell development [GO:0048468]; cellular response to cytokine stimulus [GO:0071345]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-17-mediated signaling pathway [GO:0097400]; JNK cascade [GO:0007254]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin production [GO:0002637]; response to interleukin-1 [GO:0070555]; signal transduction [GO:0007165]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000122; GO:0000209; GO:0001503; GO:0001701; GO:0001843; GO:0002637; GO:0002726; GO:0004842; GO:0005164; GO:0005634; GO:0005737; GO:0005811; GO:0005829; GO:0005886; GO:0005938; GO:0006955; GO:0006974; GO:0007165; GO:0007249; GO:0007250; GO:0007254; GO:0008270; GO:0009887; GO:0009898; GO:0016567; GO:0019221; GO:0019886; GO:0019901; GO:0030316; GO:0031435; GO:0031624; GO:0031625; GO:0031663; GO:0031666; GO:0031996; GO:0032147; GO:0032735; GO:0032743; GO:0032755; GO:0032813; GO:0032991; GO:0033209; GO:0035631; GO:0042088; GO:0042102; GO:0042475; GO:0042802; GO:0042826; GO:0042981; GO:0043011; GO:0043122; GO:0043123; GO:0043422; GO:0043507; GO:0045453; GO:0045672; GO:0045892; GO:0045944; GO:0046330; GO:0046849; GO:0047485; GO:0048468; GO:0048471; GO:0048661; GO:0050852; GO:0051091; GO:0051092; GO:0051865; GO:0061630; GO:0070498; GO:0070534; GO:0070555; GO:0071222; GO:0071345; GO:0097400; GO:1901224; GO:1904996; GO:2000679 49009 XR_006391559.1 273 121 134 109 163 NA NA NA NA NA NA 49010 XM_044315746.1 7 0 4 0 0 NA NA NA NA NA NA 49011 XM_029344898.2 0 6 25 0 80 NA NA NA NA NA NA 49012 XM_029352573.2 348 572 140 327 403 Q28199 8.86e-48 Cyclin-dependent kinase 5 activator 1 (CDK5 activator 1) (Cyclin-dependent kinase 5 regulatory subunit 1) (TPKII regulatory subunit) [Cleaved into: Cyclin-dependent kinase 5 activator 1, p35 (p35); Cyclin-dependent kinase 5 activator 1, p25 (p25) (Tau protein kinase II 23 kDa subunit) (p23)] Bos taurus (Bovine) axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; brain development [GO:0007420]; cerebellum development [GO:0021549]; embryo development ending in birth or egg hatching [GO:0009792]; ephrin receptor signaling pathway [GO:0048013]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; G1 to G0 transition involved in cell differentiation [GO:0070315]; hippocampus development [GO:0021766]; ionotropic glutamate receptor signaling pathway [GO:0035235]; layer formation in cerebral cortex [GO:0021819]; negative regulation of DNA-templated transcription [GO:0045892]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein targeting to membrane [GO:0090314]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of dendritic spine morphogenesis [GO:0061001]; rhythmic process [GO:0048511]; serine phosphorylation of STAT protein [GO:0042501]; superior olivary nucleus maturation [GO:0021722] GO:0000307; GO:0001764; GO:0002020; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005886; GO:0007158; GO:0007213; GO:0007411; GO:0007413; GO:0007420; GO:0009792; GO:0014069; GO:0016020; GO:0016301; GO:0016533; GO:0018107; GO:0019901; GO:0021549; GO:0021722; GO:0021766; GO:0021819; GO:0030182; GO:0030424; GO:0030425; GO:0030426; GO:0031116; GO:0031175; GO:0031594; GO:0032956; GO:0035235; GO:0035255; GO:0042501; GO:0043005; GO:0043014; GO:0043025; GO:0043197; GO:0043204; GO:0043292; GO:0043525; GO:0043539; GO:0045296; GO:0045860; GO:0045892; GO:0048013; GO:0048471; GO:0048487; GO:0048511; GO:0051015; GO:0061001; GO:0061575; GO:0070315; GO:0090314 49013 XM_044312904.1 10 108 79 132 40 Q9WVM6 2.6e-41 Tolloid-like protein 2 (EC 3.4.24.-) Mus musculus (Mouse) cell differentiation [GO:0030154]; dorsal/ventral pattern formation [GO:0009953]; negative regulation of skeletal muscle tissue growth [GO:0048632]; protein processing [GO:0016485] GO:0004222; GO:0005509; GO:0005615; GO:0008270; GO:0009953; GO:0016485; GO:0030154; GO:0048632 49014 XM_029350137.2 244 81 115 123 112 Q54T82 1.18e-46 Putative leucine-rich repeat-containing protein DDB_G0281931 Dictyostelium discoideum (Social amoeba) NA GO:0016020 49015 XM_029337652.2 0 32 0 52 0 NA NA NA NA NA NA 49016 XM_029328856.2 234 185 123 132 260 Q68CZ6 6.27e-69 HAUS augmin-like complex subunit 3 Homo sapiens (Human) cell division [GO:0051301]; centrosome cycle [GO:0007098]; spindle assembly [GO:0051225] GO:0005813; GO:0005829; GO:0007098; GO:0051225; GO:0051301; GO:0070652; GO:0072686; GO:1990498 49017 XM_029353272.2 687 548 367 490 425 A4IIM3 2.48e-114 Target of rapamycin complex 2 subunit MAPKAP1 (TORC2 subunit MAPKAP1) (Mitogen-activated protein kinase 2-associated protein 1) (Stress-activated map kinase-interacting protein 1) (SAPK-interacting protein 1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0031932 49018 XM_044307008.1 105 87 40 88 64 Q99986 9.36e-124 Serine/threonine-protein kinase VRK1 (EC 2.7.11.1) (Vaccinia-related kinase 1) Homo sapiens (Human) cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; Golgi disassembly [GO:0090166]; mitotic nuclear membrane disassembly [GO:0007077]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of protein localization to chromatin [GO:0120187]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165] GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005795; GO:0005829; GO:0006468; GO:0006974; GO:0007077; GO:0007165; GO:0018105; GO:0019901; GO:0035175; GO:0042393; GO:0046777; GO:0051301; GO:0072354; GO:0090166; GO:0106310; GO:0120187 49019 XM_044318616.1 2 12 0 13 0 NA NA NA NA NA NA 49020 XM_029345634.2 58 17 11 40 55 Q09840 1.21e-89 Alpha-amylase 2 (EC 3.2.1.1) (1,4-alpha-D-glucan glucanohydrolase) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) carbohydrate catabolic process [GO:0016052]; fungal-type cell wall biogenesis [GO:0009272] GO:0004556; GO:0005509; GO:0009272; GO:0009897; GO:0016052 49021 XM_044318533.1 183 98 77 70 122 A0A974CYQ5 5.79e-108 NA NA NA NA 49022 XM_044315328.1 2 10 24 43 29 NA NA NA NA NA NA 49023 XM_044320055.1 19 22 16 32 18 NA NA NA NA NA NA 49024 XR_003824619.2 572 847 555 687 643 P12394 4.15e-81 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Gallus gallus (Chicken) hormone biosynthetic process [GO:0042446]; progesterone metabolic process [GO:0042448]; steroid biosynthetic process [GO:0006694]; steroid metabolic process [GO:0008202] GO:0004508; GO:0005506; GO:0006694; GO:0008202; GO:0016020; GO:0020037; GO:0042446; GO:0042448; GO:0047442 49025 XR_003824619.2 572 847 555 687 643 P12394 4.15e-81 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Gallus gallus (Chicken) hormone biosynthetic process [GO:0042446]; progesterone metabolic process [GO:0042448]; steroid biosynthetic process [GO:0006694]; steroid metabolic process [GO:0008202] GO:0004508; GO:0005506; GO:0006694; GO:0008202; GO:0016020; GO:0020037; GO:0042446; GO:0042448; GO:0047442 49026 XM_044315894.1 2 0 9 0 6 NA NA NA NA NA NA 49027 XM_029333405.2 15 10 4 5 33 NA NA NA NA NA NA 49028 XM_044312510.1 88 52 54 149 84 NA NA NA NA NA NA 49029 XM_044320156.1 2002 0 1536 0 0 P61765 0 Syntaxin-binding protein 1 (N-Sec1) (Protein unc-18 homolog 1) (Unc18-1) (Protein unc-18 homolog A) (Unc-18A) (p67) (rbSec1) Rattus norvegicus (Rat) axon target recognition [GO:0007412]; cellular response to type II interferon [GO:0071346]; developmental process involved in reproduction [GO:0003006]; establishment of localization in cell [GO:0051649]; exocytosis [GO:0006887]; intracellular protein transport [GO:0006886]; long-term synaptic depression [GO:0060292]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of SNARE complex assembly [GO:0035544]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; neuromuscular synaptic transmission [GO:0007274]; neuron apoptotic process [GO:0051402]; neurotransmitter secretion [GO:0007269]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of exocytosis [GO:0045921]; positive regulation of glutamate secretion, neurotransmission [GO:1903296]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of vesicle docking [GO:0106022]; presynaptic dense core vesicle exocytosis [GO:0099525]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; regulation of acrosomal vesicle exocytosis [GO:2000367]; regulation of synaptic vesicle priming [GO:0010807]; regulation of vesicle fusion [GO:0031338]; response to estradiol [GO:0032355]; SNARE complex assembly [GO:0035493]; synaptic vesicle maturation [GO:0016188]; synaptic vesicle priming [GO:0016082]; vesicle docking involved in exocytosis [GO:0006904]; vesicle-mediated transport [GO:0016192] GO:0000149; GO:0002576; GO:0003006; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0006886; GO:0006887; GO:0006904; GO:0007269; GO:0007274; GO:0007412; GO:0010807; GO:0016082; GO:0016188; GO:0016192; GO:0017075; GO:0019901; GO:0019904; GO:0019905; GO:0030141; GO:0030424; GO:0031091; GO:0031333; GO:0031338; GO:0032229; GO:0032355; GO:0032991; GO:0035493; GO:0035544; GO:0042802; GO:0043195; GO:0043274; GO:0043306; GO:0043524; GO:0045335; GO:0045921; GO:0045956; GO:0047485; GO:0048471; GO:0048787; GO:0050821; GO:0051402; GO:0051649; GO:0060090; GO:0060292; GO:0070527; GO:0071346; GO:0072659; GO:0098688; GO:0098793; GO:0098794; GO:0098831; GO:0098888; GO:0098978; GO:0099523; GO:0099525; GO:0106022; GO:1903296; GO:2000367 49030 XM_029342407.2 58 66 238 184 138 Q0DXS3 8.85e-26 Probable RNA-dependent RNA polymerase 1 (OsRDR1) (EC 2.7.7.48) Oryza sativa subsp. japonica (Rice) positive regulation of post-transcriptional gene silencing [GO:0060148]; response to salicylic acid [GO:0009751]; response to virus [GO:0009615]; siRNA processing [GO:0030422]; wax biosynthetic process [GO:0010025] GO:0003723; GO:0003968; GO:0009615; GO:0009751; GO:0010025; GO:0030422; GO:0031380; GO:0060148 49031 XM_029349091.2 2180 1676 1355 1481 1181 Q99MK9 2.74e-68 Ras association domain-containing protein 1 (Protein 123F2) Mus musculus (Mouse) cell cycle [GO:0007049]; cellular response to DNA damage stimulus [GO:0006974]; positive regulation of protein ubiquitination [GO:0031398]; protein stabilization [GO:0050821]; Ras protein signal transduction [GO:0007265]; regulation of cell cycle [GO:0051726]; regulation of cell cycle G1/S phase transition [GO:1902806]; signal transduction [GO:0007165] GO:0000922; GO:0005634; GO:0005737; GO:0005815; GO:0005874; GO:0006974; GO:0007049; GO:0007165; GO:0007265; GO:0015630; GO:0031267; GO:0031398; GO:0042802; GO:0046872; GO:0047485; GO:0050821; GO:0051726; GO:1902806 49032 XR_006392724.1 319 81 119 428 679 NA NA NA NA NA NA 49033 XM_044327876.1 19 5 0 10 23 NA NA NA NA NA NA 49034 XM_029333421.2 12 0 1 5 42 NA NA NA NA NA NA 49035 XR_006395528.1 177 190 30 286 88 NA NA NA NA NA NA 49036 XM_029350852.2 181 127 80 246 59 NA NA NA NA NA NA 49037 XM_029354693.2 34 153 179 110 612 NA NA NA NA NA NA 49038 XR_006394561.1 542 601 123 512 65 NA NA NA NA NA NA 49039 XM_044323221.1 33 17 13 40 21 NA NA NA NA NA NA 49040 XR_006398084.1 423 409 356 507 617 Q1JPJ9 6.86e-30 Protein-lysine N-methyltransferase EEF2KMT (EC 2.1.1.-) (eEF2-lysine methyltransferase) (eEF2-KMT) Bos taurus (Bovine) peptidyl-lysine trimethylation [GO:0018023] GO:0005737; GO:0016279; GO:0018023; GO:0018024 49041 XM_044329292.1 85 83 88 202 86 NA NA NA NA NA NA 49042 XM_044316801.1 125 871 20 92 84 NA NA NA NA NA NA 49043 XM_044316469.1 0 0 0 7 0 NA NA NA NA NA NA 49044 XM_044315367.1 20 1 0 0 9 NA NA NA NA NA NA 49045 XM_044326623.1 0 0 0 10 0 NA NA NA NA NA NA 49046 XM_029332342.2 0 0 0 24 0 NA NA NA NA NA NA 49047 XR_006395022.1 10 3 0 0 12 NA NA NA NA NA NA 49048 XM_029347182.2 302 34 33 360 66 Q08DM7 3.6e-129 Neuronal-specific septin-3 Bos taurus (Bovine) cytoskeleton-dependent cytokinesis [GO:0061640] GO:0003924; GO:0005525; GO:0005940; GO:0015630; GO:0031105; GO:0032153; GO:0043005; GO:0060090; GO:0061640; GO:0098793; GO:0099569 49049 XM_044326427.1 3 12 21 2 1 NA NA NA NA NA NA 49050 XM_029333966.2 3 0 0 58 20 NA NA NA NA NA NA 49051 XM_044319321.1 1 3 0 2 30 NA NA NA NA NA NA 49052 XM_029325558.2 0 39 0 0 0 A7S7F2 0 Bystin Nematostella vectensis (Starlet sea anemone) rRNA processing [GO:0006364] GO:0005730; GO:0005737; GO:0006364; GO:0030515; GO:0030688 49053 XR_006391322.1 32 2 10 43 35 NA NA NA NA NA NA 49054 XM_044314144.1 8 0 0 7 41 NA NA NA NA NA NA 49055 XM_044323153.1 0 0 13 0 0 NA NA NA NA NA NA 49056 XM_044316102.1 0 17 1 0 26 NA NA NA NA NA NA 49057 XM_029333563.2 701 601 304 666 898 P50533 0 Structural maintenance of chromosomes protein 2 (SMC protein 2) (SMC-2) (Chromosome assembly protein XCAP-E) (Chromosome-associated protein E) Xenopus laevis (African clawed frog) cell cycle [GO:0007049]; cell division [GO:0051301]; chromosome condensation [GO:0030261] GO:0005524; GO:0005634; GO:0005694; GO:0005829; GO:0007049; GO:0016887; GO:0030261; GO:0051301 49058 XM_044322509.1 11 16 0 0 48 NA NA NA NA NA NA 49059 XM_044321842.1 17 0 0 0 0 O95260 1.66e-132 Arginyl-tRNA--protein transferase 1 (Arginyltransferase 1) (R-transferase 1) (EC 2.3.2.8) (Arginine-tRNA--protein transferase 1) Homo sapiens (Human) proteasomal protein catabolic process [GO:0010498]; protein arginylation [GO:0016598] GO:0004057; GO:0005634; GO:0005737; GO:0010498; GO:0016598 49060 XM_029334334.2 969 1035 603 824 787 NA NA NA NA NA NA 49061 XR_006396543.1 0 0 0 0 29 NA NA NA NA NA NA 49062 XM_044320541.1 23 3 0 60 20 B9K8C0 8.14e-33 Probable GTP-binding protein EngB Thermotoga neapolitana (strain ATCC 49049 / DSM 4359 / NBRC 107923 / NS-E) division septum assembly [GO:0000917] GO:0000917; GO:0005525; GO:0046872 49063 XM_029341887.2 288 208 115 373 381 Q9HBF4 0 Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (SR3) (Tandem FYVE fingers-1) Homo sapiens (Human) cellular response to starvation [GO:0009267]; lipid droplet formation [GO:0140042]; macroautophagy [GO:0016236] GO:0000407; GO:0005545; GO:0005547; GO:0005739; GO:0005776; GO:0005783; GO:0005789; GO:0005794; GO:0005795; GO:0005811; GO:0008270; GO:0009267; GO:0016236; GO:0032266; GO:0043325; GO:0044233; GO:0048471; GO:0097629; GO:0140042; GO:1990462 49064 XR_003822824.2 15 0 16 10 16 NA NA NA NA NA NA 49065 XR_006393589.1 286 97 267 272 108 NA NA NA NA NA NA 49066 XM_029358403.2 754 518 475 690 784 Q8N1B4 0 Vacuolar protein sorting-associated protein 52 homolog (SAC2 suppressor of actin mutations 2-like protein) Homo sapiens (Human) ectodermal cell differentiation [GO:0010668]; embryonic ectodermal digestive tract development [GO:0048611]; endocytic recycling [GO:0032456]; Golgi to vacuole transport [GO:0006896]; lysosomal transport [GO:0007041]; protein targeting [GO:0006605]; retrograde transport, endosome to Golgi [GO:0042147]; vesicle-mediated cholesterol transport [GO:0090119] GO:0000938; GO:0005794; GO:0005829; GO:0006605; GO:0006896; GO:0007041; GO:0010008; GO:0010668; GO:0016020; GO:0019905; GO:0032456; GO:0032588; GO:0042147; GO:0048471; GO:0048611; GO:0055037; GO:0090119; GO:1990745 49067 XM_029355724.1 38 17 3 39 10 P23760 9.47e-52 Paired box protein Pax-3 (HuP2) Homo sapiens (Human) anatomical structure development [GO:0048856]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; muscle organ development [GO:0007517]; nervous system development [GO:0007399]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; sensory perception of sound [GO:0007605] GO:0000785; GO:0000978; GO:0000981; GO:0003700; GO:0005654; GO:0006357; GO:0006915; GO:0007399; GO:0007517; GO:0007605; GO:0009887; GO:0043565; GO:0045893; GO:0045944; GO:0048856; GO:0071837; GO:1990837 49068 XR_006397736.1 46 0 30 42 29 NA NA NA NA NA NA 49069 XM_029337218.2 1658 937 673 1059 994 Q6ZMW3 0 Echinoderm microtubule-associated protein-like 6 (EMAP-6) (Echinoderm microtubule-associated protein-like 5-like) Homo sapiens (Human) NA GO:0005737; GO:0005874; GO:0008017 49070 XM_029337218.2 1658 937 673 1059 994 Q6ZMW3 1.04e-144 Echinoderm microtubule-associated protein-like 6 (EMAP-6) (Echinoderm microtubule-associated protein-like 5-like) Homo sapiens (Human) NA GO:0005737; GO:0005874; GO:0008017 49071 XM_029337218.2 1658 937 673 1059 994 Q6ZMW3 4.86e-123 Echinoderm microtubule-associated protein-like 6 (EMAP-6) (Echinoderm microtubule-associated protein-like 5-like) Homo sapiens (Human) NA GO:0005737; GO:0005874; GO:0008017 49072 XM_044310434.1 81 36 78 65 115 NA NA NA NA NA NA 49073 XR_003828625.2 31 30 5 17 76 NA NA NA NA NA NA 49074 XR_003826485.2 34 40 10 57 42 NA NA NA NA NA NA 49075 XM_029356975.2 162 67 124 156 131 Q5ZJ69 8.92e-46 AT-rich interactive domain-containing protein 5B (ARID domain-containing protein 5B) Gallus gallus (Chicken) adipose tissue development [GO:0060612]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000976; GO:0003713; GO:0005634; GO:0006357; GO:0051091; GO:0060612 49076 XM_029356975.2 162 67 124 156 131 Q5ZJ69 1.69e-27 AT-rich interactive domain-containing protein 5B (ARID domain-containing protein 5B) Gallus gallus (Chicken) adipose tissue development [GO:0060612]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000976; GO:0003713; GO:0005634; GO:0006357; GO:0051091; GO:0060612 49077 XM_029327701.2 47 49 19 41 22 NA NA NA NA NA NA 49078 XM_029325490.2 108 13 24 36 87 NA NA NA NA NA NA 49079 XM_044321276.1 135 55 97 34 109 NA NA NA NA NA NA 49080 XM_044313485.1 74 21 8 57 66 NA NA NA NA NA NA 49081 XM_029337758.2 561 465 440 495 579 NA NA NA NA NA NA 49082 XM_044324831.1 0 0 7 0 5 P35067 8.26e-85 Histone H2B Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 49083 XM_044310974.1 6 6 3 23 0 NA NA NA NA NA NA 49084 XR_006392497.1 15 0 0 0 8 NA NA NA NA NA NA 49085 XM_029347379.2 36 9 14 35 64 NA NA NA NA NA NA 49086 XR_006397786.1 0 88 0 0 0 NA NA NA NA NA NA 49087 XM_029324304.2 2099 1939 1015 2632 2667 P36956 6.82e-157 Sterol regulatory element-binding protein 1 (SREBP-1) (Class D basic helix-loop-helix protein 1) (bHLHd1) (Sterol regulatory element-binding transcription factor 1) [Cleaved into: Processed sterol regulatory element-binding protein 1 (Transcription factor SREBF1)] Homo sapiens (Human) aging [GO:0007568]; cellular response to fatty acid [GO:0071398]; cellular response to starvation [GO:0009267]; cholesterol biosynthetic process [GO:0006695]; circadian rhythm [GO:0007623]; fat cell differentiation [GO:0045444]; insulin receptor signaling pathway [GO:0008286]; insulin secretion [GO:0030073]; lipid biosynthetic process [GO:0008610]; lipid localization [GO:0010876]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of insulin secretion [GO:0046676]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of triglyceride biosynthetic process [GO:0010867]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of fatty acid metabolic process [GO:0019217]; regulation of heart rate by chemical signal [GO:0003062]; regulation of lipid storage [GO:0010883]; regulation of protein stability [GO:0031647]; regulation of protein targeting to mitochondrion [GO:1903214]; regulation of transcription by RNA polymerase II [GO:0006357]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to food [GO:0032094]; response to glucagon [GO:0033762]; response to glucose [GO:0009749]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; response to xenobiotic stimulus [GO:0009410]; SREBP signaling pathway [GO:0032933] GO:0000122; GO:0000139; GO:0000785; GO:0000977; GO:0000978; GO:0000981; GO:0001221; GO:0001228; GO:0003062; GO:0003677; GO:0003682; GO:0003700; GO:0004879; GO:0005634; GO:0005635; GO:0005654; GO:0005737; GO:0005783; GO:0005789; GO:0005829; GO:0006357; GO:0006629; GO:0006695; GO:0007568; GO:0007623; GO:0008286; GO:0008610; GO:0009267; GO:0009410; GO:0009749; GO:0010867; GO:0010876; GO:0010883; GO:0012507; GO:0019217; GO:0019901; GO:0030073; GO:0030324; GO:0031065; GO:0031647; GO:0032094; GO:0032526; GO:0032570; GO:0032810; GO:0032933; GO:0032991; GO:0033762; GO:0042789; GO:0044877; GO:0045444; GO:0045471; GO:0045542; GO:0045944; GO:0046676; GO:0046983; GO:0051591; GO:0071398; GO:1902895; GO:1903146; GO:1903214; GO:1990837 49088 XM_044326449.1 11 0 5 2 9 NA NA NA NA NA NA 49089 XM_044317414.1 0 24 20 72 98 NA NA NA NA NA NA 49090 XR_006392780.1 0 0 2 0 8 NA NA NA NA NA NA 49091 XM_044310640.1 77 71 65 91 94 NA NA NA NA NA NA 49092 XR_003828184.2 61 151 46 69 155 NA NA NA NA NA NA 49093 XM_029339667.2 1377 842 476 653 436 Q93ZE5 9.5e-62 Probable acylpyruvase FAHD1, mitochondrial (EC 3.7.1.5) (Fumarylacetoacetate hydrolase domain-containing protein 1) (FAH domain-containing protein 1) Arabidopsis thaliana (Mouse-ear cress) NA GO:0005507; GO:0005739; GO:0005829; GO:0018773; GO:0047621 49094 XM_029333766.2 303 322 244 162 241 NA NA NA NA NA NA 49095 XR_006397568.1 122 65 112 120 91 NA NA NA NA NA NA 49096 XM_029352176.2 90 81 26 73 68 NA NA NA NA NA NA 49097 XM_029350221.2 371 84 66 200 554 Q9R0Z9 7.9e-161 Rho GTPase-activating protein 7 (Deleted in liver cancer 1 protein homolog) (DLC-1) (Rho-type GTPase-activating protein 7) (START domain-containing protein 12) (StARD12) (StAR-related lipid transfer protein 12) Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of phospholipase C activity [GO:0007202]; apoptotic process [GO:0006915]; cytoskeleton organization [GO:0007010]; focal adhesion assembly [GO:0048041]; forebrain development [GO:0030900]; heart morphogenesis [GO:0003007]; hindbrain morphogenesis [GO:0021575]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of stress fiber assembly [GO:0051497]; neural tube closure [GO:0001843]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; regulation of Rho protein signal transduction [GO:0035023]; signal transduction [GO:0007165] GO:0001725; GO:0001843; GO:0003007; GO:0005096; GO:0005634; GO:0005737; GO:0005829; GO:0005884; GO:0005901; GO:0005925; GO:0006915; GO:0006919; GO:0007010; GO:0007165; GO:0007202; GO:0008285; GO:0008289; GO:0008360; GO:0017166; GO:0021575; GO:0030036; GO:0030336; GO:0030864; GO:0030900; GO:0032587; GO:0032956; GO:0035023; GO:0035024; GO:0035307; GO:0042169; GO:0043274; GO:0045121; GO:0048041; GO:0051497; GO:0051895; GO:1900119 49098 XM_029350221.2 371 84 66 200 554 Q9R0Z9 4.42e-24 Rho GTPase-activating protein 7 (Deleted in liver cancer 1 protein homolog) (DLC-1) (Rho-type GTPase-activating protein 7) (START domain-containing protein 12) (StARD12) (StAR-related lipid transfer protein 12) Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of phospholipase C activity [GO:0007202]; apoptotic process [GO:0006915]; cytoskeleton organization [GO:0007010]; focal adhesion assembly [GO:0048041]; forebrain development [GO:0030900]; heart morphogenesis [GO:0003007]; hindbrain morphogenesis [GO:0021575]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of stress fiber assembly [GO:0051497]; neural tube closure [GO:0001843]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; regulation of Rho protein signal transduction [GO:0035023]; signal transduction [GO:0007165] GO:0001725; GO:0001843; GO:0003007; GO:0005096; GO:0005634; GO:0005737; GO:0005829; GO:0005884; GO:0005901; GO:0005925; GO:0006915; GO:0006919; GO:0007010; GO:0007165; GO:0007202; GO:0008285; GO:0008289; GO:0008360; GO:0017166; GO:0021575; GO:0030036; GO:0030336; GO:0030864; GO:0030900; GO:0032587; GO:0032956; GO:0035023; GO:0035024; GO:0035307; GO:0042169; GO:0043274; GO:0045121; GO:0048041; GO:0051497; GO:0051895; GO:1900119 49099 XR_006393271.1 0 0 0 52 131 NA NA NA NA NA NA 49100 XM_044320871.1 20 0 11 0 54 E2RQ08 0 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (Ribophorin I) (RPN-I) (Ribophorin-1) Canis lupus familiaris (Dog) (Canis familiaris) protein glycosylation [GO:0006486]; protein N-linked glycosylation via asparagine [GO:0018279] GO:0005791; GO:0005829; GO:0006486; GO:0008250; GO:0018279 49101 XM_044316612.1 142 277 118 177 127 Q6VGS5 3.46e-67 Protein Daple (Coiled-coil domain-containing protein 88C) (Dvl-associating protein with a high frequency of leucine residues) Mus musculus (Mouse) apical constriction [GO:0003383]; cytoplasmic microtubule organization [GO:0031122]; cytoskeleton-dependent intracellular transport [GO:0030705]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-canonical Wnt signaling pathway [GO:0035567]; protein destabilization [GO:0031648]; regulation of protein phosphorylation [GO:0001932]; small GTPase mediated signal transduction [GO:0007264]; stress-activated protein kinase signaling cascade [GO:0031098] GO:0001932; GO:0001965; GO:0003383; GO:0005085; GO:0005109; GO:0005737; GO:0005813; GO:0005829; GO:0007264; GO:0008017; GO:0030054; GO:0030165; GO:0030705; GO:0031098; GO:0031122; GO:0031648; GO:0035567; GO:0042802; GO:0043621; GO:0051959; GO:0070161; GO:0090090 49102 XM_029331003.2 3989 2021 2482 2442 2419 Q60803 5.16e-114 TNF receptor-associated factor 3 (EC 2.3.2.27) (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (RING-type E3 ubiquitin transferase TRAF3) Mus musculus (Mouse) apoptotic process [GO:0006915]; innate immune response [GO:0045087]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of JNK cascade [GO:0046330]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of cytokine production [GO:0001817]; regulation of defense response to virus [GO:0050688]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of interferon-beta production [GO:0032648]; regulation of proteolysis [GO:0030162]; Toll signaling pathway [GO:0008063]; toll-like receptor signaling pathway [GO:0002224]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0001817; GO:0002224; GO:0005164; GO:0005739; GO:0005768; GO:0006915; GO:0008063; GO:0008270; GO:0009898; GO:0016740; GO:0019901; GO:0019903; GO:0030162; GO:0031625; GO:0031996; GO:0032088; GO:0032648; GO:0033209; GO:0035631; GO:0042802; GO:0042981; GO:0043122; GO:0045087; GO:0046330; GO:0050688; GO:0070534 49103 XM_044324647.1 22 20 39 16 87 NA NA NA NA NA NA 49104 XM_044328431.1 2519 1598 782 2143 2019 NA NA NA NA NA NA 49105 XM_044310571.1 160 110 193 202 318 NA NA NA NA NA NA 49106 XR_006398161.1 426 158 165 326 178 NA NA NA NA NA NA 49107 XM_029341793.2 2 0 0 20 0 NA NA NA NA NA NA 49108 XM_029358748.2 2344 1373 870 1667 1914 Q95LD9 7.39e-68 Aryl hydrocarbon receptor (Ah receptor) (AhR) Delphinapterus leucas (Beluga whale) cAMP-mediated signaling [GO:0019933]; cell cycle [GO:0007049]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; circadian regulation of gene expression [GO:0032922]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of T cell mediated immune response to tumor cell [GO:0002841]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of adaptive immune response [GO:0002819]; regulation of B cell proliferation [GO:0030888]; response to toxic substance [GO:0009636]; response to xenobiotic stimulus [GO:0009410] GO:0001094; GO:0001223; GO:0002819; GO:0002841; GO:0004879; GO:0005634; GO:0005737; GO:0005829; GO:0007049; GO:0009410; GO:0009636; GO:0017025; GO:0019933; GO:0030888; GO:0032922; GO:0034753; GO:0045892; GO:0045893; GO:0045944; GO:0046982; GO:0051879; GO:0060090; GO:0061629; GO:0070888; GO:0071320; GO:1904322; GO:1904613; GO:1990837 49109 XM_044311499.1 0 0 3 9 0 NA NA NA NA NA NA 49110 XM_029347980.2 3704 2940 1934 3039 3332 Q791V5 3.36e-71 Mitochondrial carrier homolog 2 (Met-induced mitochondrial protein) Mus musculus (Mouse) cellular response to radiation [GO:0071478]; establishment of protein localization to mitochondrial membrane involved in mitochondrial fission [GO:0090152]; hematopoietic stem cell homeostasis [GO:0061484]; hematopoietic stem cell migration [GO:0035701]; hepatocyte apoptotic process [GO:0097284]; lactate metabolic process [GO:0006089]; lipid homeostasis [GO:0055088]; mitochondrial ATP synthesis coupled electron transport [GO:0042775]; negative regulation of glycolytic process [GO:0045820]; negative regulation of mitochondrial membrane potential [GO:0010917]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902231]; positive regulation of stem cell differentiation [GO:2000738]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein localization to mitochondrion [GO:0070585]; regulation of mitochondrial fusion [GO:0010635]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108] GO:0005739; GO:0005741; GO:0005743; GO:0006089; GO:0010635; GO:0010917; GO:0016020; GO:0032977; GO:0035701; GO:0042775; GO:0043065; GO:0043280; GO:0045040; GO:0045820; GO:0055088; GO:0061484; GO:0070585; GO:0071478; GO:0090152; GO:0097284; GO:1902108; GO:1902231; GO:2000738 49111 XM_029336117.2 199 469 3009 356 760 NA NA NA NA NA NA 49112 XM_044313932.1 128 140 81 120 39 NA NA NA NA NA NA 49113 XM_029323737.2 3787 2285 4 4878 1697 Q6PDK2 6.62e-178 Histone-lysine N-methyltransferase 2D (Lysine N-methyltransferase 2D) (EC 2.1.1.364) (ALL1-related protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 2) Mus musculus (Mouse) heterochromatin formation [GO:0031507]; histone H3-K4 dimethylation [GO:0044648]; histone H3-K4 monomethylation [GO:0097692]; histone H3-K4 trimethylation [GO:0080182]; in utero embryonic development [GO:0001701]; oocyte growth [GO:0001555]; oogenesis [GO:0048477]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression [GO:0010468]; response to estrogen [GO:0043627] GO:0000976; GO:0001228; GO:0001555; GO:0001701; GO:0003713; GO:0005654; GO:0008284; GO:0010468; GO:0031507; GO:0033148; GO:0035097; GO:0042393; GO:0042800; GO:0043627; GO:0044648; GO:0044666; GO:0045944; GO:0046872; GO:0048477; GO:0080182; GO:0097692; GO:0140945 49114 XM_029323737.2 3787 2285 4 4878 1697 Q6PDK2 8.31e-78 Histone-lysine N-methyltransferase 2D (Lysine N-methyltransferase 2D) (EC 2.1.1.364) (ALL1-related protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 2) Mus musculus (Mouse) heterochromatin formation [GO:0031507]; histone H3-K4 dimethylation [GO:0044648]; histone H3-K4 monomethylation [GO:0097692]; histone H3-K4 trimethylation [GO:0080182]; in utero embryonic development [GO:0001701]; oocyte growth [GO:0001555]; oogenesis [GO:0048477]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression [GO:0010468]; response to estrogen [GO:0043627] GO:0000976; GO:0001228; GO:0001555; GO:0001701; GO:0003713; GO:0005654; GO:0008284; GO:0010468; GO:0031507; GO:0033148; GO:0035097; GO:0042393; GO:0042800; GO:0043627; GO:0044648; GO:0044666; GO:0045944; GO:0046872; GO:0048477; GO:0080182; GO:0097692; GO:0140945 49115 XM_029323737.2 3787 2285 4 4878 1697 Q6PDK2 1.9e-66 Histone-lysine N-methyltransferase 2D (Lysine N-methyltransferase 2D) (EC 2.1.1.364) (ALL1-related protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 2) Mus musculus (Mouse) heterochromatin formation [GO:0031507]; histone H3-K4 dimethylation [GO:0044648]; histone H3-K4 monomethylation [GO:0097692]; histone H3-K4 trimethylation [GO:0080182]; in utero embryonic development [GO:0001701]; oocyte growth [GO:0001555]; oogenesis [GO:0048477]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression [GO:0010468]; response to estrogen [GO:0043627] GO:0000976; GO:0001228; GO:0001555; GO:0001701; GO:0003713; GO:0005654; GO:0008284; GO:0010468; GO:0031507; GO:0033148; GO:0035097; GO:0042393; GO:0042800; GO:0043627; GO:0044648; GO:0044666; GO:0045944; GO:0046872; GO:0048477; GO:0080182; GO:0097692; GO:0140945 49116 XM_029323737.2 3787 2285 4 4878 1697 Q6PDK2 3.38e-26 Histone-lysine N-methyltransferase 2D (Lysine N-methyltransferase 2D) (EC 2.1.1.364) (ALL1-related protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 2) Mus musculus (Mouse) heterochromatin formation [GO:0031507]; histone H3-K4 dimethylation [GO:0044648]; histone H3-K4 monomethylation [GO:0097692]; histone H3-K4 trimethylation [GO:0080182]; in utero embryonic development [GO:0001701]; oocyte growth [GO:0001555]; oogenesis [GO:0048477]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression [GO:0010468]; response to estrogen [GO:0043627] GO:0000976; GO:0001228; GO:0001555; GO:0001701; GO:0003713; GO:0005654; GO:0008284; GO:0010468; GO:0031507; GO:0033148; GO:0035097; GO:0042393; GO:0042800; GO:0043627; GO:0044648; GO:0044666; GO:0045944; GO:0046872; GO:0048477; GO:0080182; GO:0097692; GO:0140945 49117 XM_029345190.2 0 181 0 0 26 Q9UKJ5 3.19e-52 Cysteine-rich hydrophobic domain-containing protein 2 (BrX-like translocated in leukemia) Homo sapiens (Human) NA GO:0005794; GO:0005798; GO:0005886; GO:0043231 49118 XM_029349305.2 8 9 0 0 53 NA NA NA NA NA NA 49119 XM_044326368.1 41 26 21 121 28 NA NA NA NA NA NA 49120 XM_029338419.2 34954 43879 34676 33319 19529 O13085 6.12e-27 Cytochrome c oxidase subunit 6A, mitochondrial (Cytochrome c oxidase polypeptide VIa) Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) oxidative phosphorylation [GO:0006119] GO:0005751; GO:0006119; GO:0016491 49121 XM_044317942.1 212 14 9 380 0 NA NA NA NA NA NA 49122 XM_029344983.2 75 3 3 0 0 Q8CIE2 7.76e-140 Zinc finger MIZ domain-containing protein 2 (PIAS-like protein Zimp7) Mus musculus (Mouse) positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0005634; GO:0005654; GO:0005739; GO:0006357; GO:0008270; GO:0030374; GO:0043596; GO:0045944 49123 XM_044317358.1 435 82 79 386 114 NA NA NA NA NA NA 49124 XR_006394739.1 317 295 346 577 552 NA NA NA NA NA NA 49125 XM_044314867.1 1 5 9 6 17 NA NA NA NA NA NA 49126 XM_044327299.1 18 8 27 37 71 Q09575 1.49e-25 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 49127 XM_029335475.2 1037 1726 564 523 555 NA NA NA NA NA NA 49128 XM_029330703.2 0 33 47 0 42 P29119 6.7e-120 Furin-1 (EC 3.4.21.75) (Dibasic-processing enzyme) (Paired basic amino acid residue-cleaving enzyme) (PACE) Xenopus laevis (African clawed frog) positive regulation of transforming growth factor beta1 activation [GO:1901394]; proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0005794; GO:0005886; GO:0006508; GO:0010008; GO:0046872; GO:1901394 49129 XM_044324373.1 127 559 105 92 352 NA NA NA NA NA NA 49130 XM_044313463.1 594 510 456 695 1026 Q8VC12 0 Urocanate hydratase (Urocanase) (EC 4.2.1.49) (Imidazolonepropionate hydrolase) Mus musculus (Mouse) histidine catabolic process [GO:0006548]; histidine catabolic process to glutamate and formamide [GO:0019556]; histidine catabolic process to glutamate and formate [GO:0019557] GO:0005829; GO:0006548; GO:0016153; GO:0019556; GO:0019557 49131 XM_029334386.2 526 0 128 102 456 Q04073 1.44e-113 DNA-binding protein P3A2 Strongylocentrotus purpuratus (Purple sea urchin) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357 49132 XM_044309629.1 9 2 1 1 3 NA NA NA NA NA NA 49133 XM_029333139.2 702 442 320 448 454 Q29RZ2 0 Peptidylprolyl isomerase domain and WD repeat-containing protein 1 (EC 5.2.1.8) Bos taurus (Bovine) mRNA processing [GO:0006397]; protein peptidyl-prolyl isomerization [GO:0000413]; RNA splicing [GO:0008380] GO:0000413; GO:0003755; GO:0006397; GO:0008380; GO:0016018; GO:0016604; GO:0071013 49134 XM_029343322.2 53 52 72 34 101 NA NA NA NA NA NA 49135 XM_029332840.2 171 67 80 123 215 Q16281 8.41e-80 Cyclic nucleotide-gated cation channel alpha-3 (Cone photoreceptor cGMP-gated channel subunit alpha) (Cyclic nucleotide-gated channel alpha-3) (CNG channel alpha-3) (CNG-3) (CNG3) Homo sapiens (Human) cation transmembrane transport [GO:0098655]; cation transport [GO:0006812]; inorganic cation import across plasma membrane [GO:0098659]; response to cAMP [GO:0051591]; response to corticosteroid [GO:0031960]; response to magnesium ion [GO:0032026]; signal transduction [GO:0007165]; visual perception [GO:0007601] GO:0005222; GO:0005223; GO:0005737; GO:0005886; GO:0006812; GO:0007165; GO:0007601; GO:0008022; GO:0015276; GO:0017071; GO:0030425; GO:0030553; GO:0031960; GO:0032026; GO:0043194; GO:0043204; GO:0044877; GO:0051591; GO:0097386; GO:0098655; GO:0098659; GO:1902495 49136 XM_044313699.1 889 3524 451 422 2971 NA NA NA NA NA NA 49137 XM_044318295.1 1880 835 103 778 1638 NA NA NA NA NA NA 49138 XR_006397397.1 365 355 410 503 179 NA NA NA NA NA NA 49139 XM_044310125.1 136 0 0 0 0 NA NA NA NA NA NA 49140 XM_029330836.2 273 285 106 692 302 NA NA NA NA NA NA 49141 XM_044326955.1 24 19 26 45 70 NA NA NA NA NA NA 49142 XM_029337696.2 7932 8925 5418 7184 4077 Q24439 1.45e-50 ATP synthase subunit O, mitochondrial (Oligomycin sensitivity conferral protein) (OSCP) Drosophila melanogaster (Fruit fly) proton motive force-driven ATP synthesis [GO:0015986]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776]; proton transmembrane transport [GO:1902600] GO:0000274; GO:0005739; GO:0015986; GO:0042776; GO:0045261; GO:0046933; GO:1902600 49143 XM_029349789.2 375 358 131 213 207 NA NA NA NA NA NA 49144 XM_029339055.2 248 78 115 205 233 P11833 0 Tubulin beta chain (Beta-tubulin) Paracentrotus lividus (Common sea urchin) microtubule-based process [GO:0007017] GO:0003924; GO:0005200; GO:0005525; GO:0005737; GO:0005874; GO:0007017; GO:0046872 49145 XR_006395530.1 82 0 2 51 48 P53992 0 Protein transport protein Sec24C (SEC24-related protein C) Homo sapiens (Human) COPII-coated vesicle cargo loading [GO:0090110]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; in utero embryonic development [GO:0001701]; intracellular protein transport [GO:0006886] GO:0000149; GO:0001701; GO:0005789; GO:0005829; GO:0006886; GO:0006888; GO:0008270; GO:0012507; GO:0030127; GO:0070971; GO:0090110 49146 XM_044323230.1 84 66 87 189 56 NA NA NA NA NA NA 49147 XM_029323625.2 92 87 30 50 29 NA NA NA NA NA NA 49148 XM_044308923.1 11 0 2 0 1 NA NA NA NA NA NA 49149 XM_029329893.2 58 0 0 0 0 O31463 1.14e-53 Homocysteine S-methyltransferase YbgG (EC 2.1.1.10) (S-methylmethionine:homocysteine methyltransferase) Bacillus subtilis (strain 168) methionine biosynthetic process [GO:0009086]; methylation [GO:0032259]; S-methylmethionine cycle [GO:0033528] GO:0008270; GO:0008898; GO:0009086; GO:0032259; GO:0033528; GO:0061627 49150 XM_029330810.2 848 750 515 751 590 Q0MQF0 2.12e-23 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (Complex I-B22) (CI-B22) (NADH-ubiquinone oxidoreductase B22 subunit) Pan troglodytes (Chimpanzee) mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrial respiratory chain complex I assembly [GO:0032981] GO:0005747; GO:0006120; GO:0032981 49151 XM_044321810.1 0 9 7 0 5 NA NA NA NA NA NA 49152 XM_044315212.1 505 261 360 573 697 P30622 1.03e-35 CAP-Gly domain-containing linker protein 1 (Cytoplasmic linker protein 1) (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed-Sternberg intermediate filament-associated protein) (Restin) Homo sapiens (Human) cytoplasmic microtubule organization [GO:0031122]; microtubule bundle formation [GO:0001578]; mitotic cell cycle [GO:0000278]; positive regulation of microtubule polymerization [GO:0031116] GO:0000278; GO:0000776; GO:0001578; GO:0001726; GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0005874; GO:0005882; GO:0008017; GO:0008270; GO:0015630; GO:0015631; GO:0030659; GO:0031116; GO:0031122; GO:0042802; GO:0051010 49153 XM_044315212.1 505 261 360 573 697 P30622 3.88e-32 CAP-Gly domain-containing linker protein 1 (Cytoplasmic linker protein 1) (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed-Sternberg intermediate filament-associated protein) (Restin) Homo sapiens (Human) cytoplasmic microtubule organization [GO:0031122]; microtubule bundle formation [GO:0001578]; mitotic cell cycle [GO:0000278]; positive regulation of microtubule polymerization [GO:0031116] GO:0000278; GO:0000776; GO:0001578; GO:0001726; GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0005874; GO:0005882; GO:0008017; GO:0008270; GO:0015630; GO:0015631; GO:0030659; GO:0031116; GO:0031122; GO:0042802; GO:0051010 49154 XM_044315212.1 505 261 360 573 697 P30622 1.29e-24 CAP-Gly domain-containing linker protein 1 (Cytoplasmic linker protein 1) (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed-Sternberg intermediate filament-associated protein) (Restin) Homo sapiens (Human) cytoplasmic microtubule organization [GO:0031122]; microtubule bundle formation [GO:0001578]; mitotic cell cycle [GO:0000278]; positive regulation of microtubule polymerization [GO:0031116] GO:0000278; GO:0000776; GO:0001578; GO:0001726; GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0005874; GO:0005882; GO:0008017; GO:0008270; GO:0015630; GO:0015631; GO:0030659; GO:0031116; GO:0031122; GO:0042802; GO:0051010 49155 XR_006397224.1 93 6 50 0 0 NA NA NA NA NA NA 49156 XM_044308573.1 56 8 0 0 135 NA NA NA NA NA NA 49157 XM_029349577.2 258 84 125 360 172 Q5R5D8 3.88e-74 Gamma-butyrobetaine dioxygenase (EC 1.14.11.1) (Gamma-butyrobetaine hydroxylase) (Gamma-BBH) (Gamma-butyrobetaine,2-oxoglutarate dioxygenase) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) carnitine biosynthetic process [GO:0045329] GO:0005506; GO:0005737; GO:0008270; GO:0008336; GO:0045329 49158 XM_044315137.1 11 2 8 2 1 NA NA NA NA NA NA 49159 XR_006392442.1 0 19 26 11 0 NA NA NA NA NA NA 49160 XM_029341559.2 1735 2048 1549 2383 2599 NA NA NA NA NA NA 49161 XM_044322164.1 366 99 101 227 137 NA NA NA NA NA NA 49162 XM_044323715.1 0 0 8 6 1 NA NA NA NA NA NA 49163 XM_029348021.2 669 579 403 509 691 A6H8Y1 6.55e-27 Transcription factor TFIIIB component B'' homolog (Transcription factor IIIB 150) (TFIIIB150) (Transcription factor-like nuclear regulator) Homo sapiens (Human) RNA polymerase III preinitiation complex assembly [GO:0070898] GO:0000126; GO:0001156; GO:0005654; GO:0070898 49164 XM_029336615.2 0 35 0 0 0 NA NA NA NA NA NA 49165 XR_006395770.1 0 32 3 0 21 NA NA NA NA NA NA 49166 XM_029332447.2 50 12 4 12 12 NA NA NA NA NA NA 49167 XM_044322374.1 102 0 35 105 90 NA NA NA NA NA NA 49168 XR_006398097.1 23 7 49 19 39 NA NA NA NA NA NA 49169 XM_044324767.1 195 196 273 772 394 P35546 1.77e-82 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; anatomical structure morphogenesis [GO:0009653]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006919; GO:0007156; GO:0007158; GO:0007169; GO:0007399; GO:0009410; GO:0009653; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030182; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0098797; GO:2001241 49170 XR_006391918.1 219 135 120 371 159 NA NA NA NA NA NA 49171 XM_044316657.1 36 11 9 21 20 NA NA NA NA NA NA 49172 XM_044316784.1 31 8 25 7 9 NA NA NA NA NA NA 49173 XM_029345491.2 1274 1530 1120 1666 2219 Q8N0W4 3.26e-78 Neuroligin-4, X-linked (Neuroligin X) (HNLX) Homo sapiens (Human) adult behavior [GO:0030534]; brainstem development [GO:0003360]; cell-cell junction organization [GO:0045216]; cerebellum development [GO:0021549]; chemical synaptic transmission [GO:0007268]; learning [GO:0007612]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of excitatory postsynaptic potential [GO:0090394]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; organ growth [GO:0035265]; postsynaptic membrane assembly [GO:0097104]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; social behavior [GO:0035176]; synapse organization [GO:0050808]; synaptic vesicle endocytosis [GO:0048488]; vocalization behavior [GO:0071625] GO:0003360; GO:0005886; GO:0007158; GO:0007268; GO:0007612; GO:0009986; GO:0016020; GO:0021549; GO:0030182; GO:0030425; GO:0030534; GO:0031404; GO:0035176; GO:0035265; GO:0038023; GO:0042043; GO:0042803; GO:0045202; GO:0045216; GO:0048488; GO:0050804; GO:0050808; GO:0050839; GO:0060076; GO:0071625; GO:0090394; GO:0097104; GO:0097105; GO:0097110; GO:0098793; GO:0098839; GO:0098983; GO:0098985; GO:0099054; GO:0099634 49174 XM_029358121.2 1380 1236 798 1308 1034 Q6EE31 0 T-complex protein 1 subunit theta (TCP-1-theta) (CCT-theta) Gallus gallus (Chicken) protein folding [GO:0006457] GO:0005524; GO:0005815; GO:0005832; GO:0006457; GO:0016887; GO:0042995; GO:0051082; GO:0140662 49175 XR_006397209.1 137 180 163 80 148 NA NA NA NA NA NA 49176 XM_044320845.1 637 294 438 533 582 Q63415 3.4e-103 Proprotein convertase subtilisin/kexin type 6 (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin-like proprotein convertase 4) (SPC4) (Subtilisin/kexin-like protease PACE4) Rattus norvegicus (Rat) determination of left/right symmetry [GO:0007368]; glycoprotein metabolic process [GO:0009100]; nerve growth factor production [GO:0032902]; peptide hormone processing [GO:0016486]; protein processing [GO:0016485]; secretion by cell [GO:0032940]; zygotic determination of anterior/posterior axis, embryo [GO:0007354] GO:0004175; GO:0004252; GO:0005615; GO:0007354; GO:0007368; GO:0008201; GO:0009100; GO:0009986; GO:0016020; GO:0016485; GO:0016486; GO:0032902; GO:0032940; GO:0048406; GO:0062023 49177 XM_044314904.1 421 232 213 222 270 NA NA NA NA NA NA 49178 XM_044318271.1 373 162 71 384 221 NA NA NA NA NA NA 49179 XM_044329159.1 31 1 0 9 11 NA NA NA NA NA NA 49180 XM_029345991.2 4 0 0 1 12 NA NA NA NA NA NA 49181 XM_029338870.2 876 347 601 873 696 NA NA NA NA NA NA 49182 XM_044319573.1 5 5 11 9 4 NA NA NA NA NA NA 49183 XM_044327704.1 279 612 355 391 278 NA NA NA NA NA NA 49184 XM_044319059.1 0 0 100 0 0 NA NA NA NA NA NA 49185 XM_044318777.1 0 288 45 0 0 NA NA NA NA NA NA 49186 XM_029346936.2 224 51 72 137 138 NA NA NA NA NA NA 49187 XM_044320555.1 23 23 12 5 36 B8V7S0 0 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 49188 XR_003824932.2 17 0 37 10 31 NA NA NA NA NA NA 49189 XM_044316101.1 16 12 22 0 10 O46640 2.28e-46 Amine sulfotransferase (EC 2.8.2.3) (AST-RB1) (Sulfotransferase 3A1) (ST3A1) Oryctolagus cuniculus (Rabbit) NA GO:0005737; GO:0047685 49190 XM_029355496.2 0 0 0 0 223 Q9JJZ8 1.22e-139 Cyclic nucleotide-gated cation channel alpha-3 (Cone photoreceptor cGMP-gated channel subunit alpha) (Cyclic nucleotide-gated channel alpha-3) (CNG channel alpha-3) (CNG-3) (CNG3) Mus musculus (Mouse) cation transmembrane transport [GO:0098655]; cation transport [GO:0006812]; inorganic cation import across plasma membrane [GO:0098659]; ion transmembrane transport [GO:0034220]; response to cAMP [GO:0051591]; response to magnesium ion [GO:0032026]; retinal cone cell development [GO:0046549]; visual perception [GO:0007601] GO:0001750; GO:0005221; GO:0005222; GO:0005223; GO:0005737; GO:0005886; GO:0006812; GO:0007601; GO:0008022; GO:0017071; GO:0030425; GO:0030553; GO:0032026; GO:0034220; GO:0043025; GO:0043194; GO:0043204; GO:0044877; GO:0046549; GO:0051591; GO:0097386; GO:0098655; GO:0098659; GO:0120199; GO:1902495 49191 XR_006393581.1 35 1 26 62 16 NA NA NA NA NA NA 49192 XM_044324878.1 110 41 57 217 162 NA NA NA NA NA NA 49193 XM_044311477.1 3 0 0 0 15 NA NA NA NA NA NA 49194 XM_044314238.1 22 5 16 28 0 A0A2P1BRQ0 4.45e-77 Cytolytic toxin-alpha (Sp-CTx-alpha) Scorpaena plumieri (Spotted scorpionfish) hemolysis in another organism [GO:0044179] GO:0005576; GO:0044179; GO:0090729 49195 XR_006397783.1 51 74 23 44 63 NA NA NA NA NA NA 49196 XM_044313146.1 364 239 160 513 390 Q32LN4 6.33e-102 Cilia- and flagella-associated protein 45 Bos taurus (Bovine) NA GO:0005879; GO:0031514 49197 XR_006395786.1 55 857 10 149 43 NA NA NA NA NA NA 49198 XM_044307822.1 1 0 0 0 31 NA NA NA NA NA NA 49199 XM_029351871.2 249 69 89 210 171 Q56X76 2.89e-71 DEAD-box ATP-dependent RNA helicase 39 (EC 3.6.4.13) Arabidopsis thaliana (Mouse-ear cress) chloroplast rRNA processing [GO:1901259]; mitochondrial large ribosomal subunit assembly [GO:1902775]; ribulose bisphosphate carboxylase complex assembly [GO:0110102] GO:0003724; GO:0003729; GO:0005524; GO:0005739; GO:0009507; GO:0016887; GO:0070180; GO:0110102; GO:1901259; GO:1902775 49200 XM_029342686.2 225 386 69 242 174 Q9NZL6 6.1e-126 Ral guanine nucleotide dissociation stimulator-like 1 (RalGDS-like 1) Homo sapiens (Human) positive regulation of GTPase activity [GO:0043547]; Ras protein signal transduction [GO:0007265]; small GTPase mediated signal transduction [GO:0007264] GO:0005085; GO:0005829; GO:0005886; GO:0007264; GO:0007265; GO:0043547 49201 XM_044317715.1 38 24 59 63 82 NA NA NA NA NA NA 49202 XM_044320359.1 123 154 94 210 133 NA NA NA NA NA NA 49203 XM_044326575.1 10 6 0 19 89 NA NA NA NA NA NA 49204 XM_029328539.2 3084 3155 2850 3832 4514 Q5RC80 9.72e-137 RNA-binding protein 39 (RNA-binding motif protein 39) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) mRNA processing [GO:0006397]; regulation of mRNA splicing, via spliceosome [GO:0048024]; RNA splicing [GO:0008380] GO:0003723; GO:0006397; GO:0008380; GO:0016607; GO:0032991; GO:0034451; GO:0048024; GO:0050733 49205 XR_006395675.1 0 2 0 39 4 NA NA NA NA NA NA 49206 XM_029349269.2 786 513 593 508 712 Q6ZMT4 9.85e-166 Lysine-specific demethylase 7A (JmjC domain-containing histone demethylation protein 1D) (Lysine-specific demethylase 7) ([histone H3]-dimethyl-L-lysine9 demethylase 7A) (EC 1.14.11.65) Homo sapiens (Human) chromatin organization [GO:0006325]; midbrain development [GO:0030901]; positive regulation of DNA-templated transcription [GO:0045893]; protein demethylation [GO:0006482]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0003712; GO:0005506; GO:0005634; GO:0005654; GO:0005730; GO:0006325; GO:0006357; GO:0006482; GO:0008270; GO:0016706; GO:0030901; GO:0032452; GO:0032454; GO:0035064; GO:0035575; GO:0045893; GO:0051864; GO:0071558; GO:0140683 49207 XM_044316840.1 87 290 12 16 51 NA NA NA NA NA NA 49208 XM_029354858.2 19 16 17 8 59 Q59E83 2.36e-29 Neuropeptide receptor 22 Caenorhabditis elegans determination of adult lifespan [GO:0008340]; negative regulation of feeding behavior [GO:2000252]; negative regulation of locomotion [GO:0040013]; neuropeptide signaling pathway [GO:0007218]; positive regulation of oviposition [GO:1901046] GO:0005886; GO:0007218; GO:0008188; GO:0008340; GO:0040013; GO:1901046; GO:2000252 49209 XM_029328348.2 223 215 103 468 346 B0JZG0 0 Solute carrier family 23 member 2 (Na(+)/L-ascorbic acid transporter 2) (Sodium-dependent vitamin C transporter 2) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) sodium ion transport [GO:0006814] GO:0006814; GO:0015229; GO:0015293; GO:0098590 49210 XR_006391949.1 122 103 28 584 10 NA NA NA NA NA NA 49211 XR_003827537.2 22 931 0 0 7 NA NA NA NA NA NA 49212 XM_029333167.2 362 238 139 249 205 Q9HAD4 3.41e-59 WD repeat-containing protein 41 Homo sapiens (Human) autophagy [GO:0006914]; negative regulation of exocytosis [GO:0045920]; negative regulation of immune response [GO:0050777]; positive regulation of GTPase activity [GO:0043547]; regulation of autophagy [GO:0010506] GO:0005737; GO:0005765; GO:0006914; GO:0010506; GO:0032045; GO:0043547; GO:0045920; GO:0050777 49213 XM_044324731.1 8 15 18 9 65 NA NA NA NA NA NA 49214 XR_006391817.1 20 0 59 75 64 NA NA NA NA NA NA 49215 XM_029336769.2 894 728 408 473 552 A7T0W1 1.58e-42 Protein UXT homolog Nematostella vectensis (Starlet sea anemone) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000785; GO:0003712; GO:0003714; GO:0006357 49216 XM_029357212.2 3517 2952 1776 2658 1510 Q5ZK84 3.18e-135 Aldo-keto reductase family 1 member A1 (EC 1.1.1.2) (Alcohol dehydrogenase [NADP(+)]) (Aldehyde reductase) Gallus gallus (Chicken) aldehyde catabolic process [GO:0046185]; cellular detoxification of aldehyde [GO:0110095]; lipid metabolic process [GO:0006629] GO:0004032; GO:0005829; GO:0006629; GO:0016324; GO:0046185; GO:0110095 49217 XM_044308587.1 207 103 76 208 95 NA NA NA NA NA NA 49218 XM_029348523.2 0 6 22 4 8 NA NA NA NA NA NA 49219 XM_044324143.1 12 4 18 16 30 NA NA NA NA NA NA 49220 XM_029341804.2 238 123 173 166 319 NA NA NA NA NA NA 49221 XM_044306796.1 43 54 53 56 57 P36915 1.86e-166 Guanine nucleotide-binding protein-like 1 (GTP-binding protein HSR1) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; signal transduction [GO:0007165]; T cell mediated immunity [GO:0002456] GO:0002456; GO:0003924; GO:0005198; GO:0005525; GO:0005615; GO:0005634; GO:0006974; GO:0007165 49222 XR_006392330.1 18 1 11 0 14 NA NA NA NA NA NA 49223 XM_029336679.2 0 0 0 0 76 NA NA NA NA NA NA 49224 XM_029337162.2 343 216 197 428 777 NA NA NA NA NA NA 49225 XM_029341463.2 57 82 51 126 90 NA NA NA NA NA NA 49226 XM_044314658.1 1 9 0 5 0 Q14191 1.32e-37 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN (DNA helicase, RecQ-like type 3) (RecQ protein-like 2) (Werner syndrome protein) [Includes: 3'-5' exonuclease (EC 3.1.-.-); ATP-dependent helicase (EC 3.6.4.12)] Homo sapiens (Human) aging [GO:0007568]; base-excision repair [GO:0006284]; brain development [GO:0007420]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; cellular response to starvation [GO:0009267]; cellular senescence [GO:0090398]; DNA duplex unwinding [GO:0032508]; DNA metabolic process [GO:0006259]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; G-quadruplex DNA unwinding [GO:0044806]; multicellular organism aging [GO:0010259]; positive regulation of hydrolase activity [GO:0051345]; positive regulation of strand invasion [GO:0098530]; protein localization to nucleolus [GO:1902570]; regulation of growth rate [GO:0040009]; replication fork processing [GO:0031297]; replicative senescence [GO:0090399]; response to oxidative stress [GO:0006979]; response to UV-C [GO:0010225]; t-circle formation [GO:0090656]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; telomeric D-loop disassembly [GO:0061820] GO:0000287; GO:0000400; GO:0000403; GO:0000405; GO:0000723; GO:0000724; GO:0000731; GO:0000781; GO:0003677; GO:0003678; GO:0003682; GO:0004527; GO:0005524; GO:0005634; GO:0005654; GO:0005657; GO:0005694; GO:0005730; GO:0005737; GO:0005813; GO:0006259; GO:0006260; GO:0006268; GO:0006281; GO:0006284; GO:0006302; GO:0006310; GO:0006974; GO:0006979; GO:0007420; GO:0007568; GO:0008408; GO:0009267; GO:0009378; GO:0010225; GO:0010259; GO:0016607; GO:0016887; GO:0030145; GO:0031297; GO:0032201; GO:0032405; GO:0032508; GO:0040009; GO:0042803; GO:0043005; GO:0043138; GO:0044806; GO:0044877; GO:0051345; GO:0051880; GO:0061749; GO:0061820; GO:0061821; GO:0061849; GO:0070337; GO:0071480; GO:0090398; GO:0090399; GO:0090656; GO:0098530; GO:1902570; GO:1905773 49227 XR_006391794.1 0 0 0 43 66 NA NA NA NA NA NA 49228 XM_044322500.1 0 0 0 250 0 NA NA NA NA NA NA 49229 XM_029358339.2 673 621 540 775 929 Q5ZJQ8 3.9e-41 Ubiquitin-associated domain-containing protein 2 (UBA domain-containing protein 2) (Phosphoglycerate dehydrogenase-like protein 1) Gallus gallus (Chicken) negative regulation of canonical Wnt signaling pathway [GO:0090090]; Wnt signaling pathway [GO:0016055] GO:0005789; GO:0016055; GO:0090090 49230 XM_029347608.2 2867 2136 1247 2493 2552 Q969R2 9.85e-87 Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (ORP-4) (OSBP-related protein 4) Homo sapiens (Human) spermatid development [GO:0007286] GO:0005829; GO:0005886; GO:0007286; GO:0015248; GO:0015485; GO:0016020; GO:0032934; GO:0043231; GO:0097038; GO:0097440 49231 XM_044324269.1 0 1 0 1 33 B0BN95 6.53e-34 Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease) Rattus norvegicus (Rat) NA GO:0004518; GO:0005634; GO:0005737; GO:0046872 49232 XM_044317908.1 356 146 482 726 1411 NA NA NA NA NA NA 49233 XM_029346991.2 371 219 143 120 494 NA NA NA NA NA NA 49234 XR_006392272.1 0 0 0 11 0 NA NA NA NA NA NA 49235 XM_029329195.2 23065 24647 9138 14859 11269 Q2TBQ5 5.78e-121 60S ribosomal protein L7a Bos taurus (Bovine) maturation of LSU-rRNA [GO:0000470] GO:0000470; GO:0003723; GO:0016020; GO:0022625; GO:0042788; GO:0045202 49236 XM_044309396.1 13 1 0 7 1 Q99315 1.14e-84 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 49237 XM_029342114.2 0 0 0 0 18 NA NA NA NA NA NA 49238 XM_029323842.2 0 6 0 57 17 Q6TNS2 5.3e-79 p21-activated protein kinase-interacting protein 1-like (PAK1-interacting protein 1-like) Danio rerio (Zebrafish) (Brachydanio rerio) negative regulation of signal transduction [GO:0009968]; ribosomal large subunit biogenesis [GO:0042273] GO:0005730; GO:0009968; GO:0042273 49239 XM_044324721.1 92 3 0 38 85 P07949 1.33e-82 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; axon guidance [GO:0007411]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; lymphocyte migration into lymphoid organs [GO:0097021]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; posterior midgut development [GO:0007497]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006468; GO:0006919; GO:0007156; GO:0007158; GO:0007165; GO:0007169; GO:0007411; GO:0007497; GO:0009410; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0038023; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0097021; GO:0098797; GO:2001241 49240 XM_029346742.2 0 2 1 0 20 NA NA NA NA NA NA 49241 XM_029348768.2 1315 1174 863 1133 1177 Q9NUQ2 6.37e-87 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 5) (1-AGP acyltransferase 5) (1-AGPAT 5) (Lysophosphatidic acid acyltransferase epsilon) (LPAAT-epsilon) Homo sapiens (Human) acylglycerol metabolic process [GO:0006639]; CDP-diacylglycerol biosynthetic process [GO:0016024]; hematopoietic progenitor cell differentiation [GO:0002244]; phosphatidic acid biosynthetic process [GO:0006654]; phospholipid biosynthetic process [GO:0008654] GO:0002244; GO:0003841; GO:0005635; GO:0005730; GO:0005739; GO:0005741; GO:0005789; GO:0006639; GO:0006654; GO:0008654; GO:0012505; GO:0016024; GO:0016746 49242 XM_044312889.1 0 0 0 19 0 NA NA NA NA NA NA 49243 XR_006396323.1 28 68 14 20 118 NA NA NA NA NA NA 49244 XM_029326358.2 0 0 0 113 0 Q27084 8.33e-81 Tachylectin-2 (Lectin L10c) Tachypleus tridentatus (Japanese horseshoe crab) innate immune response [GO:0045087] GO:0005576; GO:0030246; GO:0045087 49245 XM_029326358.2 0 0 0 113 0 Q27084 5.96e-66 Tachylectin-2 (Lectin L10c) Tachypleus tridentatus (Japanese horseshoe crab) innate immune response [GO:0045087] GO:0005576; GO:0030246; GO:0045087 49246 XM_029347885.2 18008 11549 7579 8493 9527 NA NA NA NA NA NA 49247 XR_006396028.1 21 21 14 35 6 NA NA NA NA NA NA 49248 XM_044314217.1 275 0 303 29 638 NA NA NA NA NA NA 49249 XM_044328192.1 860 1458 894 752 1016 Q9Y5X2 3.05e-110 Sorting nexin-8 Homo sapiens (Human) early endosome to Golgi transport [GO:0034498]; intracellular protein transport [GO:0006886] GO:0005829; GO:0006886; GO:0031901; GO:0034498; GO:0035091; GO:0042802; GO:0043231 49250 XM_029350161.2 348 1366 297 298 435 J7GQ11 8.13e-78 L-tyrosine decarboxylase (TDC) (EC 4.1.1.25) Levilactobacillus brevis (Lactobacillus brevis) carboxylic acid metabolic process [GO:0019752] GO:0004837; GO:0019752; GO:0030170; GO:0036468 49251 XR_006392175.1 0 0 0 237 0 NA NA NA NA NA NA 49252 XM_044325729.1 11807 4064 4881 13309 13585 O88572 7.01e-95 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 49253 XM_044325729.1 11807 4064 4881 13309 13585 O88572 4.24e-86 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 49254 XM_044325729.1 11807 4064 4881 13309 13585 O88572 4.83e-75 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 49255 XM_044325729.1 11807 4064 4881 13309 13585 O88572 1.9e-65 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 49256 XM_044325729.1 11807 4064 4881 13309 13585 O88572 8.43e-58 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 49257 XM_044325729.1 11807 4064 4881 13309 13585 O88572 1.28e-46 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 49258 XM_044325729.1 11807 4064 4881 13309 13585 O88572 1.28e-40 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 49259 XM_044325729.1 11807 4064 4881 13309 13585 O88572 5.5e-39 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 49260 XM_044325729.1 11807 4064 4881 13309 13585 O88572 9.26e-38 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 49261 XM_044325729.1 11807 4064 4881 13309 13585 O88572 1.02e-35 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 49262 XM_044325729.1 11807 4064 4881 13309 13585 O88572 6.56e-35 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 49263 XM_044325729.1 11807 4064 4881 13309 13585 O88572 1.44e-33 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 49264 XM_044325729.1 11807 4064 4881 13309 13585 O88572 4.87e-32 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 49265 XM_044325729.1 11807 4064 4881 13309 13585 O88572 7.42e-24 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 49266 XM_044325729.1 11807 4064 4881 13309 13585 O88572 3.53e-21 Low-density lipoprotein receptor-related protein 6 (LRP-6) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; mesenchymal cell proliferation [GO:0010463]; mesodermal cell migration [GO:0008078]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; Norrin signaling pathway [GO:0110135]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:0061350]; planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:0061349]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar cell polarity pathway involved in outflow tract morphogenesis [GO:0061347]; planar cell polarity pathway involved in pericardium morphogenesis [GO:0061354]; planar cell polarity pathway involved in ventricular septum morphogenesis [GO:0061348]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuron projection development [GO:0010976]; positive regulation of ossification [GO:0045778]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial cell proliferation [GO:0050678]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; stem cell proliferation [GO:0072089]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001702; GO:0001756; GO:0001843; GO:0001933; GO:0001947; GO:0002053; GO:0003344; GO:0003401; GO:0005041; GO:0005102; GO:0005109; GO:0005769; GO:0005783; GO:0005794; GO:0005886; GO:0005901; GO:0006355; GO:0006469; GO:0007204; GO:0007268; GO:0008078; GO:0009880; GO:0009950; GO:0009952; GO:0009986; GO:0010463; GO:0010976; GO:0014029; GO:0014033; GO:0016020; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0021587; GO:0021794; GO:0021795; GO:0021861; GO:0021872; GO:0021874; GO:0021915; GO:0021943; GO:0021987; GO:0030326; GO:0030900; GO:0030901; GO:0030917; GO:0031410; GO:0034185; GO:0034392; GO:0035108; GO:0035115; GO:0035116; GO:0035261; GO:0036342; GO:0042074; GO:0042475; GO:0042733; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043065; GO:0045202; GO:0045444; GO:0045599; GO:0045778; GO:0045780; GO:0045787; GO:0045893; GO:0045944; GO:0046849; GO:0048596; GO:0048699; GO:0048705; GO:0050678; GO:0050680; GO:0051091; GO:0051593; GO:0060021; GO:0060026; GO:0060042; GO:0060059; GO:0060070; GO:0060284; GO:0060325; GO:0060444; GO:0060535; GO:0060596; GO:0060603; GO:0061310; GO:0061324; GO:0061347; GO:0061348; GO:0061349; GO:0061350; GO:0061354; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072089; GO:0072659; GO:0090009; GO:0090118; GO:0090179; GO:0090244; GO:0090245; GO:0098609; GO:0110135; GO:1990851; GO:1990909; GO:2000051; GO:2000149; GO:2000151; GO:2000162; GO:2000164; GO:2000166; GO:2000168; GO:2000648 49267 XM_029348045.2 140 178 171 0 756 A8MU46 6.45e-26 Smoothelin-like protein 1 Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; muscle organ morphogenesis [GO:0048644]; negative regulation of DNA-templated transcription [GO:0045892]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of vasoconstriction [GO:0045907]; response to activity [GO:0014823]; response to xenobiotic stimulus [GO:0009410]; vasoconstriction [GO:0042310] GO:0005516; GO:0005523; GO:0005634; GO:0005737; GO:0005815; GO:0008157; GO:0009410; GO:0014823; GO:0018105; GO:0030036; GO:0031430; GO:0031674; GO:0031941; GO:0042310; GO:0043292; GO:0043621; GO:0045892; GO:0045907; GO:0048644; GO:0051401; GO:0097718 49268 XM_044314953.1 28 103 0 0 0 NA NA NA NA NA NA 49269 XM_029337442.2 159 165 129 312 231 Q9NYV6 4.68e-133 RNA polymerase I-specific transcription initiation factor RRN3 (Transcription initiation factor IA) (TIF-IA) Homo sapiens (Human) cytoplasm organization [GO:0007028]; fibroblast proliferation [GO:0048144]; homeostasis of number of cells [GO:0048872]; in utero embryonic development [GO:0001701]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902254]; nucleolus organization [GO:0007000]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA-templated transcription initiation [GO:2000142]; ribosome biogenesis [GO:0042254]; transcription initiation at RNA polymerase I promoter [GO:0006361] GO:0001042; GO:0001164; GO:0001181; GO:0001701; GO:0005634; GO:0005654; GO:0005730; GO:0006361; GO:0007000; GO:0007028; GO:0042254; GO:0045893; GO:0048144; GO:0048872; GO:0072332; GO:1902254; GO:2000142 49270 XM_029354866.2 1 2 10 3 13 NA NA NA NA NA NA 49271 XM_029334735.2 1466 1119 689 810 346 Q8T773 1.19e-139 Putative malate dehydrogenase 1B (EC 1.1.1.-) Branchiostoma floridae (Florida lancelet) (Amphioxus) malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099] GO:0006099; GO:0006108; GO:0016615; GO:0016616 49272 XM_029335578.2 81 14 114 107 71 Q95M17 2.93e-117 Acidic mammalian chitinase (AMCase) (EC 3.2.1.14) (Chitin-binding protein b04) (CBPb04) Bos taurus (Bovine) apoptotic process [GO:0006915]; chitin catabolic process [GO:0006032]; immune system process [GO:0002376]; polysaccharide catabolic process [GO:0000272]; positive regulation of chemokine production [GO:0032722]; production of molecular mediator involved in inflammatory response [GO:0002532] GO:0000272; GO:0002376; GO:0002532; GO:0004568; GO:0005615; GO:0005737; GO:0006032; GO:0006915; GO:0008061; GO:0032722 49273 XR_003825284.2 35 16 3 59 22 NA NA NA NA NA NA 49274 XM_029351644.2 986 785 553 825 1001 Q5R6Y0 0 HBS1-like protein Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003746; GO:0003924; GO:0005525; GO:0110165 49275 XM_029329975.2 213 158 102 153 117 Q804Q5 1.31e-61 Fez family zinc finger protein 2 (Forebrain embryonic zinc finger-like protein 2) (Foreheadin protein) (Zinc finger protein Fez-like) Danio rerio (Zebrafish) (Brachydanio rerio) central nervous system development [GO:0007417]; central nervous system neuron development [GO:0021954]; commissural neuron axon guidance [GO:0071679]; diencephalon development [GO:0021536]; forebrain development [GO:0030900]; forebrain neuron differentiation [GO:0021879]; hypothalamus development [GO:0021854]; mammillary body development [GO:0021767]; negative regulation of DNA-templated transcription [GO:0045892]; nervous system development [GO:0007399]; neuronal stem cell population maintenance [GO:0097150]; regulation of Notch signaling pathway [GO:0008593]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0007399; GO:0007417; GO:0008593; GO:0021536; GO:0021767; GO:0021854; GO:0021879; GO:0021954; GO:0030900; GO:0045892; GO:0046872; GO:0071679; GO:0097150 49276 XM_044309243.1 3 0 169 256 3 NA NA NA NA NA NA 49277 XM_044311372.1 3 0 8 1 17 Q09575 4.99e-29 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 49278 XM_044311372.1 3 0 8 1 17 Q09575 4.99e-29 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 49279 XM_029335021.2 0 108 10 0 0 Q84K35 3.46e-105 Pseudouridine-5'-phosphate glycosidase (PsiMP glycosidase) (EC 4.2.1.70) (Pseudouridine monophosphate glycosidase) Arabidopsis thaliana (Mouse-ear cress) NA GO:0004730; GO:0005777; GO:0030597; GO:0046872 49280 XM_044321061.1 0 8 0 1 72 NA NA NA NA NA NA 49281 XR_006397201.1 0 0 0 0 6 NA NA NA NA NA NA 49282 XR_006391590.1 8 56 16 13 76 O43196 0 MutS protein homolog 5 (hMSH5) Homo sapiens (Human) chiasma assembly [GO:0051026]; mismatch repair [GO:0006298] GO:0003690; GO:0005524; GO:0005634; GO:0006298; GO:0030983; GO:0051026; GO:0140664 49283 XM_044316690.1 1 0 6 1 44 C5G6D7 3.13e-40 Chondroitin sulfate ABC exolyase (EC 4.2.2.21) (Chondroitin ABC exoeliminase) (Chondroitin ABC lyase II) (Chondroitin sulfate ABC lyase II) (ChS ABC lyase II) (Chondroitinase ABC II) (cABC II) (Exochondroitinase ABC) Bacteroides thetaiotaomicron carbohydrate metabolic process [GO:0005975]; dermatan sulfate catabolic process [GO:0030209]; glycosaminoglycan catabolic process [GO:0006027] GO:0000287; GO:0005509; GO:0005576; GO:0005975; GO:0006027; GO:0030209; GO:0030246; GO:0034000; GO:0034001; GO:0042597 49284 XR_006395175.1 19 18 38 55 13 NA NA NA NA NA NA 49285 XM_044328073.1 1032 788 692 1365 1216 NA NA NA NA NA NA 49286 XM_029346727.2 0 0 0 0 37 Q5M7D8 1e-22 Protein FAM166C B Xenopus laevis (African clawed frog) NA NA 49287 XM_044321081.1 4280 2689 1787 7479 6207 P18856 2.4e-32 Collagen EMF1-alpha (Fibrillar collagen) Ephydatia muelleri (Mueller's freshwater sponge) (Spongilla muelleri) NA GO:0005201; GO:0005576; GO:0005581 49288 XR_006396053.1 0 34 21 34 0 NA NA NA NA NA NA 49289 XM_029335189.2 11623 10612 7469 11090 8532 P12716 0 Actin, cytoplasmic (EC 3.6.4.-) [Cleaved into: Actin, cytoplasmic, intermediate form] Pisaster ochraceus (Ochre sea star) (Asterias ochracea) NA GO:0005524; GO:0005737; GO:0005856; GO:0016787 49290 XM_044321458.1 18 16 8 18 35 Q80VL3 7.11e-61 Prickle planar cell polarity protein 3 (LIM domain only protein 6) (LMO-6) (Prickle-like protein 3) (Pk3) (Triple LIM domain protein 6) Mus musculus (Mouse) cell projection organization [GO:0030030] GO:0005739; GO:0005886; GO:0008270; GO:0030030 49291 XM_029357942.2 207 253 121 214 71 NA NA NA NA NA NA 49292 XM_029354026.2 26 0 13 0 48 P05363 2.18e-22 Substance-K receptor (SKR) (NK-2 receptor) (NK-2R) (Neurokinin A receptor) (Tachykinin receptor 2) Bos taurus (Bovine) positive regulation of flagellated sperm motility [GO:1902093]; regulation of uterine smooth muscle contraction [GO:0070472] GO:0004995; GO:0005886; GO:0016497; GO:0061827; GO:0070472; GO:0097225; GO:1902093 49293 XM_029349186.2 36 29 2 21 28 NA NA NA NA NA NA 49294 XM_044311766.1 106 71 0 0 10 NA NA NA NA NA NA 49295 XM_029339774.2 3610 3417 1849 3176 2781 NA NA NA NA NA NA 49296 XM_044315209.1 140 40 101 132 197 NA NA NA NA NA NA 49297 XM_044315967.1 0 164 0 90 38 NA NA NA NA NA NA 49298 XM_029341296.2 761 735 649 658 435 NA NA NA NA NA NA 49299 XM_044327132.1 44 6 43 77 11 NA NA NA NA NA NA 49300 XR_006394039.1 502 90 61 303 26 Q7RTR2 9.58e-27 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 49301 XR_006394039.1 502 90 61 303 26 Q7RTR2 8.8e-25 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 49302 XR_006394039.1 502 90 61 303 26 Q7RTR2 2.61e-23 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 49303 XR_006394039.1 502 90 61 303 26 Q7RTR2 4.71e-23 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 49304 XM_029334083.2 66 119 44 0 90 Q09081 2.73e-142 Potassium voltage-gated channel subfamily A member 2 (KC22) (Voltage-gated potassium channel subunit Kv1.2) Oryctolagus cuniculus (Rabbit) neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233] GO:0005249; GO:0005251; GO:0005789; GO:0005886; GO:0008076; GO:0014059; GO:0019228; GO:0019233; GO:0021633; GO:0030027; GO:0030424; GO:0030425; GO:0031258; GO:0032809; GO:0033010; GO:0034765; GO:0042734; GO:0043194; GO:0043204; GO:0043679; GO:0044224; GO:0045188; GO:0051260; GO:0071805 49305 XM_044322577.1 0 0 0 308 199 Q7RTR2 4.24e-62 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 49306 XM_044322577.1 0 0 0 308 199 Q7RTR2 2.01e-59 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 49307 XM_044322577.1 0 0 0 308 199 Q7RTR2 3.73e-56 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 49308 XM_044322577.1 0 0 0 308 199 Q7RTR2 2.84e-38 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 49309 XM_044319606.1 2 0 0 3 7 NA NA NA NA NA NA 49310 XM_044324960.1 25 17 14 45 45 Q96AY4 2.45e-129 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 49311 XM_044324960.1 25 17 14 45 45 Q96AY4 8.68e-127 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 49312 XM_044324960.1 25 17 14 45 45 Q96AY4 1.19e-123 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 49313 XM_044324960.1 25 17 14 45 45 Q96AY4 5.5e-122 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 49314 XM_044324960.1 25 17 14 45 45 Q96AY4 5.62e-82 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 49315 XM_044324960.1 25 17 14 45 45 Q96AY4 9.2e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 49316 XM_044313748.1 1 0 0 0 7 NA NA NA NA NA NA 49317 XM_044321590.1 71 18 66 13 244 NA NA NA NA NA NA 49318 XM_029344461.2 0 81 0 283 374 Q8K078 2.21e-102 Solute carrier organic anion transporter family member 4A1 (Organic anion-transporting polypeptide E) (OATP-E) (Sodium-independent organic anion transporter E) (Solute carrier family 21 member 12) Mus musculus (Mouse) sodium-independent organic anion transport [GO:0043252]; thyroid hormone metabolic process [GO:0042403] GO:0005886; GO:0008514; GO:0015132; GO:0015347; GO:0015349; GO:0042403; GO:0043252 49319 XM_044322255.1 876 557 383 721 727 Q9XSK8 8.13e-45 Tumor protein p73 (p53-like transcription factor) (p53-related protein) Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein tetramerization [GO:0051262] GO:0000976; GO:0000981; GO:0005634; GO:0005737; GO:0006915; GO:0007049; GO:0045944; GO:0046872; GO:0051262 49320 XM_044311731.1 16 18 9 0 7 Q80XJ3 2.76e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 49321 XM_029338622.2 83 48 0 37 0 P21521 6.97e-123 Synaptotagmin 1 (p65) Drosophila melanogaster (Fruit fly) calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; chemical synaptic transmission [GO:0007268]; clathrin-dependent synaptic vesicle endocytosis [GO:0150007]; larval locomotory behavior [GO:0008345]; neurotransmitter secretion [GO:0007269]; positive regulation of vesicle fusion [GO:0031340]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of neuromuscular synaptic transmission [GO:1900073]; regulation of pole plasm oskar mRNA localization [GO:0007317]; regulation of synapse structure or activity [GO:0050803]; rhythmic synaptic transmission [GO:0060024]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle exocytosis [GO:0016079]; vesicle-mediated transport [GO:0016192] GO:0000149; GO:0001786; GO:0005509; GO:0005544; GO:0005886; GO:0007268; GO:0007269; GO:0007317; GO:0008021; GO:0008345; GO:0014059; GO:0016020; GO:0016079; GO:0016192; GO:0017156; GO:0017158; GO:0019905; GO:0030276; GO:0030424; GO:0030672; GO:0031045; GO:0031340; GO:0031594; GO:0042803; GO:0043195; GO:0048488; GO:0048791; GO:0050803; GO:0060024; GO:0070382; GO:0071277; GO:0150007; GO:1900073 49322 XM_029349668.2 65 37 38 58 16 Q6BD04 9.24e-24 G-protein coupled receptor 54 Oreochromis niloticus (Nile tilapia) (Tilapia nilotica) NA GO:0004930; GO:0005886 49323 XM_044321594.1 1480 662 950 1343 735 Q6NYW6 5.31e-161 CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2) Danio rerio (Zebrafish) (Brachydanio rerio) cell division [GO:0051301]; establishment of mitotic spindle localization [GO:0040001]; exit from mitosis [GO:0010458]; Golgi organization [GO:0007030]; microtubule anchoring [GO:0034453]; microtubule cytoskeleton organization [GO:0000226]; microtubule nucleation [GO:0007020]; microtubule organizing center organization [GO:0031023]; mitotic spindle assembly [GO:0090307]; mitotic spindle organization [GO:0007052]; regulation of microtubule polymerization or depolymerization [GO:0031110]; regulation of microtubule-based process [GO:0032886] GO:0000226; GO:0000776; GO:0005794; GO:0005802; GO:0005815; GO:0005874; GO:0005876; GO:0005881; GO:0007020; GO:0007030; GO:0007052; GO:0008017; GO:0010458; GO:0031023; GO:0031110; GO:0031252; GO:0032587; GO:0032886; GO:0034453; GO:0040001; GO:0045180; GO:0051010; GO:0051301; GO:0072686; GO:0090307 49324 XM_044321594.1 1480 662 950 1343 735 Q6NYW6 1.32e-43 CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2) Danio rerio (Zebrafish) (Brachydanio rerio) cell division [GO:0051301]; establishment of mitotic spindle localization [GO:0040001]; exit from mitosis [GO:0010458]; Golgi organization [GO:0007030]; microtubule anchoring [GO:0034453]; microtubule cytoskeleton organization [GO:0000226]; microtubule nucleation [GO:0007020]; microtubule organizing center organization [GO:0031023]; mitotic spindle assembly [GO:0090307]; mitotic spindle organization [GO:0007052]; regulation of microtubule polymerization or depolymerization [GO:0031110]; regulation of microtubule-based process [GO:0032886] GO:0000226; GO:0000776; GO:0005794; GO:0005802; GO:0005815; GO:0005874; GO:0005876; GO:0005881; GO:0007020; GO:0007030; GO:0007052; GO:0008017; GO:0010458; GO:0031023; GO:0031110; GO:0031252; GO:0032587; GO:0032886; GO:0034453; GO:0040001; GO:0045180; GO:0051010; GO:0051301; GO:0072686; GO:0090307 49325 XM_029353144.2 99 107 104 126 68 NA NA NA NA NA NA 49326 XR_006397025.1 320 61 189 205 389 NA NA NA NA NA NA 49327 XR_003824959.2 138 56 69 118 231 NA NA NA NA NA NA 49328 XM_044318394.1 0 0 7 5 4 NA NA NA NA NA NA 49329 XM_029332770.2 389 324 116 61 433 Q9Y4E6 0 WD repeat-containing protein 7 (Rabconnectin-3 beta) (TGF-beta resistance-associated protein TRAG) Homo sapiens (Human) hematopoietic progenitor cell differentiation [GO:0002244] GO:0002244; GO:0005737 49330 XR_006391830.1 37 49 68 48 91 NA NA NA NA NA NA 49331 XM_044315679.1 7 0 1 3 0 NA NA NA NA NA NA 49332 XM_029324000.2 361 182 233 379 0 A8E7N9 8.86e-40 Growth/differentiation factor 6-B (GDF-6-B) (Growth differentiation factor 6b) (Protein dynamo) Danio rerio (Zebrafish) (Brachydanio rerio) positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; SMAD protein signal transduction [GO:0060395] GO:0005125; GO:0005615; GO:0008083; GO:0010862; GO:0060395 49333 XM_044312956.1 299 89 56 0 169 Q9NZM1 0 Myoferlin (Fer-1-like protein 3) Homo sapiens (Human) blood circulation [GO:0008015]; membrane fusion [GO:0061025]; muscle contraction [GO:0006936]; plasma membrane organization [GO:0007009]; plasma membrane repair [GO:0001778]; T-tubule organization [GO:0033292] GO:0001778; GO:0005543; GO:0005635; GO:0005886; GO:0005901; GO:0006936; GO:0007009; GO:0008015; GO:0030659; GO:0031410; GO:0031965; GO:0033292; GO:0043231; GO:0046872; GO:0061025; GO:0070062 49334 XR_006392808.1 104 106 42 53 44 NA NA NA NA NA NA 49335 XM_044323538.1 7 2 9 32 7 NA NA NA NA NA NA 49336 XM_029340414.2 0 0 1 0 10 P49285 9.83e-31 Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor) (CKA) Gallus gallus (Chicken) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; circadian rhythm [GO:0007623]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of glucose import [GO:0046325]; negative regulation of glycolytic process [GO:0045820] GO:0004930; GO:0005886; GO:0007186; GO:0007193; GO:0007623; GO:0008502; GO:0042562; GO:0043235; GO:0045820; GO:0046325; GO:1904408 49337 XM_029341595.2 498 464 402 670 547 O15160 4.19e-147 DNA-directed RNA polymerases I and III subunit RPAC1 (DNA-directed RNA polymerase I subunit C) (RNA polymerases I and III subunit AC1) (AC40) (DNA-directed RNA polymerases I and III 40 kDa polypeptide) (RPA40) (RPA39) (RPC40) Homo sapiens (Human) transcription by RNA polymerase I [GO:0006360] GO:0001054; GO:0001056; GO:0001650; GO:0003677; GO:0003899; GO:0005654; GO:0005666; GO:0005736; GO:0005829; GO:0006360; GO:0046983 49338 XM_029350832.2 1219 1411 779 1154 1215 Q8BXX9 2.42e-26 Coiled-coil domain-containing protein 169 Mus musculus (Mouse) NA NA 49339 XM_044317170.1 489 289 172 339 147 NA NA NA NA NA NA 49340 XM_029341952.2 5 17 13 43 34 Q5U3Y0 3.03e-97 Kelch domain-containing protein 10 Rattus norvegicus (Rat) positive regulation of stress-activated MAPK cascade [GO:0032874]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process via the C-end degron rule pathway [GO:0140627] GO:0005634; GO:0005737; GO:0016567; GO:0031462; GO:0032874; GO:0140627; GO:1990756 49341 XM_044315575.1 51 30 37 108 89 NA NA NA NA NA NA 49342 XM_029336488.2 178 30 121 150 177 Q5U374 6.48e-40 Kelch-like protein 12 Danio rerio (Zebrafish) (Brachydanio rerio) anterior/posterior pattern specification [GO:0009952]; convergent extension involved in axis elongation [GO:0060028]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; protein monoubiquitination [GO:0006513]; Wnt signaling pathway [GO:0016055] GO:0006513; GO:0006888; GO:0009952; GO:0014029; GO:0014032; GO:0016055; GO:0030127; GO:0030134; GO:0031463; GO:0048208; GO:0060028 49343 XM_044317989.1 35 0 0 13 1 NA NA NA NA NA NA 49344 XR_006397567.1 94 117 136 20 0 NA NA NA NA NA NA 49345 XM_029333896.2 3945 3171 4994 2808 2782 A7SE05 2.38e-96 Ubiquitin-conjugating enzyme E2 S (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme S) (Ubiquitin carrier protein S) (Ubiquitin-protein ligase S) Nematostella vectensis (Starlet sea anemone) anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; exit from mitosis [GO:0010458]; free ubiquitin chain polymerization [GO:0010994]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; protein K11-linked ubiquitination [GO:0070979]; protein polyubiquitination [GO:0000209]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000209; GO:0005524; GO:0005634; GO:0005680; GO:0006511; GO:0010458; GO:0010994; GO:0031145; GO:0051301; GO:0061631; GO:0070979; GO:1904668 49346 XM_029344760.2 3251 3475 2193 2931 4032 Q9N121 2.41e-44 Glycine cleavage system H protein, mitochondrial (Lipoic acid-containing protein) Oryctolagus cuniculus (Rabbit) glycine decarboxylation via glycine cleavage system [GO:0019464]; protein lipoylation [GO:0009249] GO:0005739; GO:0005960; GO:0009249; GO:0019464 49347 XR_006392167.1 73 0 0 0 107 NA NA NA NA NA NA 49348 XM_029344594.2 1569 1443 1307 1272 1452 Q3ZBL4 5.69e-96 Leucine zipper transcription factor-like protein 1 Bos taurus (Bovine) flagellated sperm motility [GO:0030317]; negative regulation of protein localization to ciliary membrane [GO:1903568]; negative regulation of protein localization to cilium [GO:1903565]; spermatogenesis [GO:0007283] GO:0002177; GO:0005737; GO:0005829; GO:0005929; GO:0007283; GO:0030317; GO:0042802; GO:0062063; GO:1903565; GO:1903568 49349 XM_044329186.1 63 22 38 55 33 NA NA NA NA NA NA 49350 XM_029332509.2 15 0 8 2 22 NA NA NA NA NA NA 49351 XR_006393217.1 1 0 2 9 2 E9Q5R7 2.68e-39 NACHT, LRR and PYD domains-containing protein 12 (Monarch-1) (PYRIN-containing APAF1-like protein 7) (PYPAF7) Mus musculus (Mouse) cellular response to cytokine stimulus [GO:0071345]; dendritic cell migration [GO:0036336]; ERK1 and ERK2 cascade [GO:0070371]; negative regulation of cytokine production [GO:0001818]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of signal transduction [GO:0009968]; negative regulation of Toll signaling pathway [GO:0045751]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of inflammatory response [GO:0050727] GO:0001818; GO:0005524; GO:0005737; GO:0009968; GO:0031953; GO:0032088; GO:0032692; GO:0032715; GO:0036336; GO:0038061; GO:0043122; GO:0043124; GO:0043281; GO:0045345; GO:0045751; GO:0050727; GO:0050728; GO:0070371; GO:0070373; GO:0071345; GO:1901223; GO:1901224 49352 XM_029330643.2 2783 3159 1869 3107 2203 Q0II91 5.54e-101 DnaJ homolog subfamily C member 21 Bos taurus (Bovine) NA GO:0003676; GO:0005730; GO:0005737; GO:0008270 49353 XM_044308212.1 0 0 0 0 7 Q9Z173 2.12e-74 Adhesion G protein-coupled receptor L3 (Calcium-independent alpha-latrotoxin receptor 3) (CIRL-3) (Latrophilin-3) Rattus norvegicus (Rat) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; brain development [GO:0007420]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; locomotion involved in locomotory behavior [GO:0031987]; maintenance of postsynaptic specialization structure [GO:0098880]; neuron migration [GO:0001764]; positive regulation of synapse assembly [GO:0051965]; response to cocaine [GO:0042220]; synapse assembly [GO:0007416]; synapse organization [GO:0050808] GO:0001764; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007166; GO:0007189; GO:0007416; GO:0007420; GO:0030246; GO:0030424; GO:0031987; GO:0042220; GO:0045211; GO:0050808; GO:0051965; GO:0098685; GO:0098742; GO:0098880; GO:0098978 49354 XM_029344313.2 344 125 264 240 663 Q16739 7.56e-102 Ceramide glucosyltransferase (EC 2.4.1.80) (GLCT-1) (Glucosylceramide synthase) (GCS) (Glycosylceramide synthase) (UDP-glucose ceramide glucosyltransferase) (UDP-glucose:N-acylsphingosine D-glucosyltransferase) Homo sapiens (Human) cell differentiation [GO:0030154]; cornified envelope assembly [GO:1903575]; epidermis development [GO:0008544]; establishment of skin barrier [GO:0061436]; glucosylceramide biosynthetic process [GO:0006679]; glycosphingolipid metabolic process [GO:0006687]; intestinal lipid absorption [GO:0098856]; keratinocyte differentiation [GO:0030216]; leptin-mediated signaling pathway [GO:0033210]; neuron development [GO:0048666]; protein lipidation [GO:0006497]; regulation of signal transduction [GO:0009966] GO:0000139; GO:0006497; GO:0006679; GO:0006687; GO:0008120; GO:0008544; GO:0009966; GO:0016020; GO:0030154; GO:0030216; GO:0033210; GO:0048666; GO:0061436; GO:0098856; GO:0102769; GO:1903575 49355 XM_029326906.2 7868 9016 2991 7232 7813 NA NA NA NA NA NA 49356 XM_044325368.1 4 0 16 8 24 NA NA NA NA NA NA 49357 XM_044317284.1 428 346 31 125 63 Q9CXR1 1.95e-76 Dehydrogenase/reductase SDR family member 7 (EC 1.1.1.-) (Retinal short-chain dehydrogenase/reductase 4) (retSDR4) (Short chain dehydrogenase/reductase family 34C member 1) (Protein SDR34C1) Mus musculus (Mouse) NA GO:0004090; GO:0005789; GO:0016616; GO:0052650 49358 XR_006394257.1 11 4 43 9 189 NA NA NA NA NA NA 49359 XM_044321684.1 3 0 0 33 57 E2JA28 3.15e-36 Dapdiamide synthesis protein DdaC (EC 1.-.-.-) Enterobacter agglomerans (Erwinia herbicola) (Pantoea agglomerans) antibiotic biosynthetic process [GO:0017000] GO:0016491; GO:0017000 49360 XM_029350075.2 17854 18299 10505 14414 11732 Q8STF0 3.31e-99 Calmodulin (CaM) Strongylocentrotus intermedius (Sea urchin) NA GO:0005509 49361 XM_029350075.2 17854 18299 10505 14414 11732 Q8STF0 2.93e-97 Calmodulin (CaM) Strongylocentrotus intermedius (Sea urchin) NA GO:0005509 49362 XM_029350075.2 17854 18299 10505 14414 11732 Q8STF0 3.02e-32 Calmodulin (CaM) Strongylocentrotus intermedius (Sea urchin) NA GO:0005509 49363 XM_029347119.2 2961 2530 1726 2846 2011 Q86YI8 1.61e-27 PHD finger protein 13 (Survival time-associated PHD finger protein in ovarian cancer 1) (SPOC1) Homo sapiens (Human) cell division [GO:0051301]; chromatin organization [GO:0006325]; chromosome segregation [GO:0007059]; mitotic cell cycle [GO:0000278]; mitotic chromosome condensation [GO:0007076] GO:0000278; GO:0003682; GO:0005634; GO:0005654; GO:0006325; GO:0007059; GO:0007076; GO:0035064; GO:0046872; GO:0051301 49364 XM_029343225.2 641 1030 138 210 0 NA NA NA NA NA NA 49365 XM_044322051.1 0 0 86 0 156 Q8IS64 2.84e-158 Endothelin-converting enzyme homolog (ECE) (EC 3.4.24.-) Locusta migratoria (Migratory locust) proteolysis [GO:0006508] GO:0004175; GO:0004222; GO:0005886; GO:0006508; GO:0008270 49366 XR_006398065.1 16 2 1 1 13 NA NA NA NA NA NA 49367 XM_044322141.1 2234 3970 1044 2384 3101 NA NA NA NA NA NA 49368 XM_029358439.2 89 101 62 37 89 B0V1P1 4.26e-21 Melanocortin receptor 4 (MC4-R) Danio rerio (Zebrafish) (Brachydanio rerio) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; energy homeostasis [GO:0097009]; energy reserve metabolic process [GO:0006112]; negative regulation of feeding behavior [GO:2000252]; regulation of growth [GO:0040008]; regulation of metabolic process [GO:0019222] GO:0004930; GO:0004977; GO:0004980; GO:0005737; GO:0005886; GO:0006112; GO:0007189; GO:0019222; GO:0040008; GO:0097009; GO:2000252 49369 XM_044324149.1 92 68 56 43 79 F1QGD2 2.2e-41 Probable palmitoyltransferase ZDHHC24 (EC 2.3.1.225) (DHHC domain-containing cysteine-rich protein 24) (Zinc finger DHHC domain-containing protein 24) Danio rerio (Zebrafish) (Brachydanio rerio) peptidyl-L-cysteine S-palmitoylation [GO:0018230]; protein targeting to membrane [GO:0006612] GO:0005783; GO:0005794; GO:0006612; GO:0016020; GO:0018230; GO:0019706 49370 XR_006397229.1 545 430 235 418 791 NA NA NA NA NA NA 49371 XM_029341728.2 0 5 0 320 0 Q9Z2E3 1.34e-32 Serine/threonine-protein kinase/endoribonuclease IRE2 (Endoplasmic reticulum-to-nucleus signaling 2) (Inositol-requiring protein 2) (Ire1-beta) (IRE1b) (mIre1) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)] Mus musculus (Mouse) apoptotic chromosome condensation [GO:0030263]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; IRE1-mediated unfolded protein response [GO:0036498]; mRNA processing [GO:0006397]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of JUN kinase activity [GO:0043507]; protein phosphorylation [GO:0006468]; regulation of DNA-templated transcription [GO:0006355]; response to endoplasmic reticulum stress [GO:0034976]; rRNA catabolic process [GO:0016075] GO:0000287; GO:0004519; GO:0004521; GO:0004674; GO:0005524; GO:0005783; GO:0005829; GO:0006355; GO:0006397; GO:0006468; GO:0016075; GO:0030263; GO:0034976; GO:0036498; GO:0043507; GO:0044322; GO:0045892; GO:0051082; GO:0070059; GO:0106310; GO:1990604 49372 XM_029325813.2 10 44 0 34 207 NA NA NA NA NA NA 49373 XM_044317011.1 493 1248 882 1788 1707 Q14192 1.12e-70 Four and a half LIM domains protein 2 (FHL-2) (LIM domain protein DRAL) (Skeletal muscle LIM-protein 3) (SLIM-3) Homo sapiens (Human) atrial cardiac muscle cell development [GO:0055014]; heart trabecula formation [GO:0060347]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of transcription by RNA polymerase II [GO:0000122]; osteoblast differentiation [GO:0001649]; response to hormone [GO:0009725]; ventricular cardiac muscle cell development [GO:0055015] GO:0000122; GO:0001649; GO:0003712; GO:0003714; GO:0005634; GO:0005654; GO:0005925; GO:0008134; GO:0009725; GO:0030018; GO:0042802; GO:0043066; GO:0043425; GO:0046872; GO:0055014; GO:0055015; GO:0060347; GO:0070885 49374 XM_044317011.1 493 1248 882 1788 1707 Q14192 1.4e-29 Four and a half LIM domains protein 2 (FHL-2) (LIM domain protein DRAL) (Skeletal muscle LIM-protein 3) (SLIM-3) Homo sapiens (Human) atrial cardiac muscle cell development [GO:0055014]; heart trabecula formation [GO:0060347]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of transcription by RNA polymerase II [GO:0000122]; osteoblast differentiation [GO:0001649]; response to hormone [GO:0009725]; ventricular cardiac muscle cell development [GO:0055015] GO:0000122; GO:0001649; GO:0003712; GO:0003714; GO:0005634; GO:0005654; GO:0005925; GO:0008134; GO:0009725; GO:0030018; GO:0042802; GO:0043066; GO:0043425; GO:0046872; GO:0055014; GO:0055015; GO:0060347; GO:0070885 49375 XM_044317011.1 493 1248 882 1788 1707 Q14192 4.08e-22 Four and a half LIM domains protein 2 (FHL-2) (LIM domain protein DRAL) (Skeletal muscle LIM-protein 3) (SLIM-3) Homo sapiens (Human) atrial cardiac muscle cell development [GO:0055014]; heart trabecula formation [GO:0060347]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of transcription by RNA polymerase II [GO:0000122]; osteoblast differentiation [GO:0001649]; response to hormone [GO:0009725]; ventricular cardiac muscle cell development [GO:0055015] GO:0000122; GO:0001649; GO:0003712; GO:0003714; GO:0005634; GO:0005654; GO:0005925; GO:0008134; GO:0009725; GO:0030018; GO:0042802; GO:0043066; GO:0043425; GO:0046872; GO:0055014; GO:0055015; GO:0060347; GO:0070885 49376 XM_044315844.1 21 45 7 117 58 Q7RTR2 2.09e-29 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 49377 XM_044315844.1 21 45 7 117 58 Q7RTR2 1.11e-27 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 49378 XM_044309395.1 35 30 26 55 163 NA NA NA NA NA NA 49379 XM_029331067.2 1 2 0 9 0 NA NA NA NA NA NA 49380 XM_029357274.2 149 64 378 621 259 Q16720 3.97e-113 Plasma membrane calcium-transporting ATPase 3 (PMCA3) (EC 7.2.2.10) (Plasma membrane calcium ATPase isoform 3) (Plasma membrane calcium pump isoform 3) Homo sapiens (Human) calcium ion export across plasma membrane [GO:1990034]; cellular calcium ion homeostasis [GO:0006874]; ion transmembrane transport [GO:0034220]; regulation of cardiac conduction [GO:1903779]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0005388; GO:0005516; GO:0005524; GO:0005886; GO:0006874; GO:0015085; GO:0016887; GO:0019829; GO:0030165; GO:0034220; GO:0042734; GO:0043231; GO:0046872; GO:0051480; GO:0098688; GO:0098978; GO:0098982; GO:1903561; GO:1903779; GO:1905056; GO:1990032; GO:1990034 49381 XM_029357274.2 149 64 378 621 259 Q16720 3.1e-50 Plasma membrane calcium-transporting ATPase 3 (PMCA3) (EC 7.2.2.10) (Plasma membrane calcium ATPase isoform 3) (Plasma membrane calcium pump isoform 3) Homo sapiens (Human) calcium ion export across plasma membrane [GO:1990034]; cellular calcium ion homeostasis [GO:0006874]; ion transmembrane transport [GO:0034220]; regulation of cardiac conduction [GO:1903779]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0005388; GO:0005516; GO:0005524; GO:0005886; GO:0006874; GO:0015085; GO:0016887; GO:0019829; GO:0030165; GO:0034220; GO:0042734; GO:0043231; GO:0046872; GO:0051480; GO:0098688; GO:0098978; GO:0098982; GO:1903561; GO:1903779; GO:1905056; GO:1990032; GO:1990034 49382 XM_029357274.2 149 64 378 621 259 Q16720 4.25e-32 Plasma membrane calcium-transporting ATPase 3 (PMCA3) (EC 7.2.2.10) (Plasma membrane calcium ATPase isoform 3) (Plasma membrane calcium pump isoform 3) Homo sapiens (Human) calcium ion export across plasma membrane [GO:1990034]; cellular calcium ion homeostasis [GO:0006874]; ion transmembrane transport [GO:0034220]; regulation of cardiac conduction [GO:1903779]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0005388; GO:0005516; GO:0005524; GO:0005886; GO:0006874; GO:0015085; GO:0016887; GO:0019829; GO:0030165; GO:0034220; GO:0042734; GO:0043231; GO:0046872; GO:0051480; GO:0098688; GO:0098978; GO:0098982; GO:1903561; GO:1903779; GO:1905056; GO:1990032; GO:1990034 49383 XM_044312431.1 192 627 168 1807 184 NA NA NA NA NA NA 49384 XM_029333153.2 267 70 186 393 211 NA NA NA NA NA NA 49385 XR_006396388.1 5 7 0 2 0 NA NA NA NA NA NA 49386 XM_029342912.2 905 487 399 711 718 Q8K245 3.5e-95 UV radiation resistance-associated protein Mus musculus (Mouse) autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; centrosome cycle [GO:0007098]; chromosome segregation [GO:0007059]; DNA repair [GO:0006281]; double-strand break repair via classical nonhomologous end joining [GO:0097680]; maintenance of Golgi location [GO:0051684]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; protein phosphorylation [GO:0006468]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of protein serine/threonine kinase activity [GO:0071900]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; SNARE complex assembly [GO:0035493]; spindle organization [GO:0007051]; viral entry into host cell [GO:0046718] GO:0000149; GO:0000323; GO:0000421; GO:0000775; GO:0005764; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005813; GO:0006281; GO:0006468; GO:0006890; GO:0006914; GO:0007051; GO:0007059; GO:0007098; GO:0010506; GO:0017124; GO:0030496; GO:0032465; GO:0032801; GO:0032991; GO:0035032; GO:0035493; GO:0036092; GO:0045335; GO:0046718; GO:0051684; GO:0070418; GO:0071900; GO:0097352; GO:0097680 49387 XM_044311419.1 0 1 15 0 0 NA NA NA NA NA NA 49388 XM_029341408.2 108 73 79 61 35 NA NA NA NA NA NA 49389 XM_044327285.1 2 0 0 2 15 NA NA NA NA NA NA 49390 XM_029334078.2 253 372 0 198 101 P79955 3.08e-135 Carboxy-terminal kinesin 2 (XCTK2) Xenopus laevis (African clawed frog) microtubule-based movement [GO:0007018] GO:0003777; GO:0005524; GO:0005737; GO:0005874; GO:0007018; GO:0008017 49391 XM_044327005.1 82 445 365 369 335 NA NA NA NA NA NA 49392 XM_029340399.2 0 0 0 10 10 Q8IRC7 1.13e-76 LIM/homeobox protein Awh (Protein arrowhead) Drosophila melanogaster (Fruit fly) compound eye development [GO:0048749]; imaginal disc development [GO:0007444]; neuron differentiation [GO:0030182]; regulation of DNA-templated transcription [GO:0006355]; regulation of gene expression [GO:0010468]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000977; GO:0000981; GO:0003700; GO:0005634; GO:0006355; GO:0006357; GO:0007444; GO:0010468; GO:0030182; GO:0046872; GO:0048749 49393 XM_044323788.1 298 182 112 287 301 NA NA NA NA NA NA 49394 XM_029334094.2 0 0 0 3 6 NA NA NA NA NA NA 49395 XR_006392232.1 4 1 18 0 4 NA NA NA NA NA NA 49396 XM_044311923.1 24 5 14 3 41 Q09575 1.79e-43 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 49397 XR_006392310.1 199 52 103 412 180 NA NA NA NA NA NA 49398 XM_044319279.1 4928 4182 2508 4006 1923 NA NA NA NA NA NA 49399 XM_044322860.1 55 18 46 49 10 NA NA NA NA NA NA 49400 XM_029339172.2 270 108 189 149 472 NA NA NA NA NA NA 49401 XM_029354904.2 18 9 6 1 39 NA NA NA NA NA NA 49402 XM_029335518.2 0 340 0 0 0 Q61035 0 Histidine--tRNA ligase, cytoplasmic (EC 6.1.1.21) (Histidyl-tRNA synthetase) (HisRS) Mus musculus (Mouse) histidyl-tRNA aminoacylation [GO:0006427]; mitochondrial translation [GO:0032543] GO:0004821; GO:0005524; GO:0005737; GO:0005739; GO:0005829; GO:0006427; GO:0032543; GO:0042802; GO:0042803 49403 XM_029343145.2 0 0 489 292 0 Q9VPD3 8.11e-134 Phosphatidylserine synthase (EC 2.7.8.29) Drosophila melanogaster (Fruit fly) phosphatidylserine biosynthetic process [GO:0006659] GO:0005789; GO:0006659; GO:0012505; GO:0016780; GO:0106245; GO:0106258 49404 XM_029343742.2 200 104 103 17 212 NA NA NA NA NA NA 49405 XM_029336131.2 1394 796 522 912 440 P37198 4.53e-77 Nuclear pore glycoprotein p62 (62 kDa nucleoporin) (Nucleoporin Nup62) Homo sapiens (Human) cell death [GO:0008219]; cell surface receptor signaling pathway [GO:0007166]; cellular senescence [GO:0090398]; centriole assembly [GO:0098534]; centrosome cycle [GO:0007098]; mitotic centrosome separation [GO:0007100]; mitotic metaphase plate congression [GO:0007080]; mRNA transport [GO:0051028]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of programmed cell death [GO:0043069]; negative regulation of Ras protein signal transduction [GO:0046580]; nucleocytoplasmic transport [GO:0006913]; positive regulation of centriole replication [GO:0046601]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of mitotic cytokinetic process [GO:1903438]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of protein localization to centrosome [GO:1904781]; protein import into nucleus [GO:0006606]; regulation of mitotic spindle organization [GO:0060236]; regulation of Ras protein signal transduction [GO:0046578]; regulation of signal transduction [GO:0009966]; RNA export from nucleus [GO:0006405] GO:0000922; GO:0003682; GO:0005543; GO:0005635; GO:0005643; GO:0005654; GO:0005737; GO:0005813; GO:0006405; GO:0006606; GO:0006913; GO:0007080; GO:0007098; GO:0007100; GO:0007166; GO:0008219; GO:0008285; GO:0009966; GO:0017056; GO:0030159; GO:0030544; GO:0031965; GO:0042059; GO:0042169; GO:0043066; GO:0043069; GO:0043123; GO:0043130; GO:0043407; GO:0044613; GO:0045742; GO:0045840; GO:0045893; GO:0046578; GO:0046580; GO:0046601; GO:0051028; GO:0051425; GO:0051879; GO:0060236; GO:0072686; GO:0090398; GO:0090543; GO:0098534; GO:1903438; GO:1904781; GO:1990904 49406 XM_029349538.2 1527 845 616 1487 824 Q1LZH1 6.73e-40 Mitochondrial amidoxime reducing component 2 (mARC2) (EC 1.7.-.-) (Molybdenum cofactor sulfurase C-terminal domain-containing protein 2) (MOSC domain-containing protein 2) (Moco sulfurase C-terminal domain-containing protein 2) Bos taurus (Bovine) cellular detoxification of nitrogen compound [GO:0070458]; nitrate metabolic process [GO:0042126]; nitric oxide biosynthetic process [GO:0006809] GO:0005741; GO:0005777; GO:0006809; GO:0008940; GO:0030151; GO:0030170; GO:0042126; GO:0043546; GO:0070458; GO:0098809 49407 XM_044315608.1 8 5 4 12 25 NA NA NA NA NA NA 49408 XM_044322825.1 176 120 300 222 277 D3YXG0 2.67e-21 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 49409 XM_044322053.1 232 195 108 176 444 Q8NCX0 7.67e-86 Coiled-coil domain-containing protein 150 Homo sapiens (Human) NA NA 49410 XR_006393040.1 194 1323 520 32 8 NA NA NA NA NA NA 49411 XM_029348475.2 4867 3101 1750 6196 5203 P55199 3.64e-41 RNA polymerase II elongation factor ELL (Eleven-nineteen lysine-rich leukemia protein) Homo sapiens (Human) in utero embryonic development [GO:0001701]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of transcription by RNA polymerase III [GO:0045945]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; snRNA transcription by RNA polymerase II [GO:0042795]; snRNA transcription by RNA polymerase III [GO:0042796]; transcription elongation by RNA polymerase II promoter [GO:0006368] GO:0000791; GO:0000987; GO:0001701; GO:0005654; GO:0005829; GO:0006368; GO:0008023; GO:0015030; GO:0016604; GO:0016607; GO:0019902; GO:0032786; GO:0032968; GO:0035363; GO:0042795; GO:0042796; GO:0045945 49412 XM_029339633.2 131 42 278 68 84 NA NA NA NA NA NA 49413 XM_044309078.1 945 610 631 798 1138 A0A2J6RX17 2.75e-36 NA NA NA NA 49414 XM_044309078.1 945 610 631 798 1138 A0A2J6RX17 3.63e-35 NA NA NA NA 49415 XM_029324021.2 393 168 294 361 248 Q8VIJ8 2.11e-160 GATOR complex protein NPRL3 (Nitrogen permease regulator 3-like protein) Mus musculus (Mouse) aorta morphogenesis [GO:0035909]; cardiac muscle tissue development [GO:0048738]; cellular response to amino acid starvation [GO:0034198]; negative regulation of TOR signaling [GO:0032007]; negative regulation of TORC1 signaling [GO:1904262]; positive regulation of autophagy [GO:0010508]; roof of mouth development [GO:0060021]; TORC1 signaling [GO:0038202]; ventricular septum development [GO:0003281] GO:0003281; GO:0005096; GO:0005765; GO:0010508; GO:0032007; GO:0034198; GO:0035909; GO:0038202; GO:0048738; GO:0060021; GO:1904262; GO:1990130 49416 XM_029357019.2 125 13 149 41 468 NA NA NA NA NA NA 49417 XM_029352746.2 46 0 0 684 266 NA NA NA NA NA NA 49418 XM_029345938.2 113 100 55 140 96 P35270 3.86e-48 Sepiapterin reductase (SPR) (EC 1.1.1.153) Homo sapiens (Human) nitric oxide biosynthetic process [GO:0006809]; tetrahydrobiopterin biosynthetic process [GO:0006729] GO:0004033; GO:0004757; GO:0005654; GO:0005829; GO:0006729; GO:0006809; GO:0050661; GO:0070062 49419 XM_029355391.2 441 290 178 454 565 NA NA NA NA NA NA 49420 XR_006395252.1 2 8 5 0 0 NA NA NA NA NA NA 49421 XM_029346111.2 389 146 327 263 202 NA NA NA NA NA NA 49422 XM_029341593.2 4549 7616 4654 3368 3676 Q9QYK7 2.84e-51 RING finger protein 11 (NEDD4 WW domain-binding protein 2) (Sid 1669) Mus musculus (Mouse) protein autoubiquitination [GO:0051865]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000151; GO:0005634; GO:0005769; GO:0006511; GO:0046872; GO:0051865; GO:0055037; GO:0061630 49423 XR_006397902.1 93 75 136 166 439 NA NA NA NA NA NA 49424 XM_029343144.2 1232 523 239 2648 1828 B0WWP2 4.87e-110 Kelch-like protein diablo Culex quinquefasciatus (Southern house mosquito) (Culex pungens) negative regulation of synaptic assembly at neuromuscular junction [GO:0045886]; protein ubiquitination [GO:0016567] GO:0003779; GO:0016567; GO:0045886 49425 XM_029333544.2 11 8 0 1 22 NA NA NA NA NA NA 49426 XM_029354533.2 278 172 246 199 167 NA NA NA NA NA NA 49427 XM_029323838.2 29 10 15 16 29 NA NA NA NA NA NA 49428 XM_029353877.2 0 0 14 9 14 Q8K2J9 6.37e-61 BTB/POZ domain-containing protein 6 Mus musculus (Mouse) neurogenesis [GO:0022008] GO:0005829; GO:0022008 49429 XM_029329996.2 16 154 110 140 203 NA NA NA NA NA NA 49430 XM_044315695.1 0 0 1 3 9 Q09575 2.32e-29 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 49431 XM_029339455.2 47 19 0 95 133 NA NA NA NA NA NA 49432 XM_029357575.2 768 736 506 545 459 P65349 1.48e-35 Uncharacterized methyltransferase Mb3374 (EC 2.1.1.-) Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) methylation [GO:0032259] GO:0008168; GO:0032259 49433 XM_029351254.2 38 63 0 49 80 Q924V1 3.81e-131 NADPH oxidase 4 (EC 1.6.3.-) (Kidney oxidase-1) (KOX-1) (Kidney superoxide-producing NADPH oxidase) Rattus norvegicus (Rat) aging [GO:0007568]; bone resorption [GO:0045453]; cardiac muscle cell differentiation [GO:0055007]; cell morphogenesis [GO:0000902]; cellular response to cAMP [GO:0071320]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose stimulus [GO:0071333]; cellular response to transforming growth factor beta stimulus [GO:0071560]; defense response [GO:0006952]; gene expression [GO:0010467]; heart process [GO:0003015]; homocysteine metabolic process [GO:0050667]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hydrogen peroxide biosynthetic process [GO:0010729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of stress fiber assembly [GO:0051496]; reactive oxygen species metabolic process [GO:0072593]; response to hypoxia [GO:0001666]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801] GO:0000902; GO:0001666; GO:0003015; GO:0005634; GO:0005739; GO:0005789; GO:0005886; GO:0005925; GO:0006801; GO:0006952; GO:0007568; GO:0008285; GO:0010467; GO:0010729; GO:0014911; GO:0016174; GO:0016175; GO:0016324; GO:0042554; GO:0043020; GO:0043065; GO:0043406; GO:0045453; GO:0048471; GO:0050664; GO:0050667; GO:0051496; GO:0051897; GO:0055007; GO:0061098; GO:0070374; GO:0071320; GO:0071333; GO:0071480; GO:0071560; GO:0071944; GO:0072341; GO:0072593; GO:0097038; GO:1990782; GO:2000379; GO:2000573 49434 XM_029350583.2 332 207 160 582 370 Q9C5D2 6.24e-27 F-box/LRR-repeat protein 4 (AtFBL4) Arabidopsis thaliana (Mouse-ear cress) nucleotide-excision repair [GO:0006289]; response to UV-C [GO:0010225]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0006289; GO:0010225; GO:0019005; GO:0031146 49435 XM_029327059.2 1657 1368 1927 2257 2490 P49419 0 Alpha-aminoadipic semialdehyde dehydrogenase (Alpha-AASA dehydrogenase) (EC 1.2.1.31) (Aldehyde dehydrogenase family 7 member A1) (EC 1.2.1.3) (Antiquitin-1) (Betaine aldehyde dehydrogenase) (EC 1.2.1.8) (Delta1-piperideine-6-carboxylate dehydrogenase) (P6c dehydrogenase) Homo sapiens (Human) cellular aldehyde metabolic process [GO:0006081]; choline catabolic process [GO:0042426]; glycine betaine biosynthetic process from choline [GO:0019285]; sensory perception of sound [GO:0007605] GO:0004029; GO:0004043; GO:0005634; GO:0005739; GO:0005759; GO:0005829; GO:0006081; GO:0007605; GO:0008802; GO:0019285; GO:0042426; GO:0042802; GO:0043878; GO:0070062 49436 XM_029344171.2 0 22 12 12 58 O08726 8.2e-21 Galanin receptor type 2 (GAL2-R) (GALR-2) Rattus norvegicus (Rat) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; G protein-coupled receptor signaling pathway [GO:0007186]; galanin-activated signaling pathway [GO:0090663]; inositol phosphate metabolic process [GO:0043647]; negative regulation of adenylate cyclase activity [GO:0007194]; neuron projection development [GO:0031175]; neuropeptide signaling pathway [GO:0007218]; phosphatidylinositol metabolic process [GO:0046488]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of large conductance calcium-activated potassium channel activity [GO:1902608]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0004966; GO:0005886; GO:0005929; GO:0007186; GO:0007188; GO:0007189; GO:0007194; GO:0007200; GO:0007204; GO:0007218; GO:0008528; GO:0017046; GO:0031175; GO:0042923; GO:0043647; GO:0045944; GO:0046488; GO:0090663; GO:1902608 49437 XM_044319596.1 9 0 0 0 0 NA NA NA NA NA NA 49438 XM_029349719.2 2 0 5 31 0 P11617 8.34e-24 Adenosine receptor A2a Canis lupus familiaris (Dog) (Canis familiaris) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; apoptotic signaling pathway [GO:0097190]; eating behavior [GO:0042755]; G protein-coupled adenosine receptor signaling pathway [GO:0001973]; G protein-coupled receptor signaling pathway [GO:0007186]; inhibitory postsynaptic potential [GO:0060080]; locomotory behavior [GO:0007626]; negative regulation of alpha-beta T cell activation [GO:0046636]; negative regulation of inflammatory response [GO:0050728]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; response to amphetamine [GO:0001975]; response to inorganic substance [GO:0010035]; response to purine-containing compound [GO:0014074]; synaptic transmission, dopaminergic [GO:0001963] GO:0001609; GO:0001963; GO:0001973; GO:0001975; GO:0004930; GO:0005886; GO:0007186; GO:0007189; GO:0007626; GO:0008289; GO:0010035; GO:0014074; GO:0019899; GO:0032230; GO:0042755; GO:0042802; GO:0046636; GO:0050728; GO:0060080; GO:0097190; GO:0098794; GO:2001235 49439 XM_044321969.1 0 18 15 112 20 O75486 9.69e-64 Transcription initiation protein SPT3 homolog (SPT3-like protein) Homo sapiens (Human) histone acetylation [GO:0016573]; histone H3 acetylation [GO:0043966]; monoubiquitinated histone deubiquitination [GO:0035521]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA repair [GO:0006282]; regulation of DNA-templated transcription [GO:0006355]; regulation of RNA splicing [GO:0043484]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366] GO:0000124; GO:0003713; GO:0005634; GO:0005654; GO:0006282; GO:0006355; GO:0006357; GO:0006366; GO:0016573; GO:0033276; GO:0035521; GO:0035522; GO:0043484; GO:0043966; GO:0045893; GO:0046982 49440 XM_029353973.2 343 331 327 470 523 Q9UMX1 1.88e-149 Suppressor of fused homolog (SUFUH) Homo sapiens (Human) aorta development [GO:0035904]; coronary vasculature development [GO:0060976]; cytoplasmic sequestering of transcription factor [GO:0042994]; heart looping [GO:0001947]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of hh target transcription factor activity [GO:1990787]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein import into nucleus [GO:0042308]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:1901621]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059]; neural tube closure [GO:0001843]; regulation of DNA-templated transcription [GO:0006355]; signal transduction [GO:0007165]; skin development [GO:0043588]; smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831]; smoothened signaling pathway involved in spinal cord motor neuron cell fate specification [GO:0021776]; smoothened signaling pathway involved in ventral spinal cord interneuron specification [GO:0021775]; ventricular septum development [GO:0003281] GO:0000122; GO:0001843; GO:0001947; GO:0003281; GO:0003714; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006355; GO:0007165; GO:0008013; GO:0019901; GO:0021775; GO:0021776; GO:0035904; GO:0042308; GO:0042994; GO:0043433; GO:0043588; GO:0045668; GO:0045879; GO:0060831; GO:0060976; GO:0097542; GO:0097546; GO:1901621; GO:1990787; GO:1990788; GO:2000059 49441 XM_044314284.1 28 111 35 32 117 NA NA NA NA NA NA 49442 XM_044327865.1 2 0 0 0 6 NA NA NA NA NA NA 49443 XM_029329602.2 327 286 128 205 165 Q54ZG7 8.68e-31 Transmembrane protein 234 homolog Dictyostelium discoideum (Social amoeba) NA GO:0016020 49444 XM_044323203.1 35 4 92 70 92 NA NA NA NA NA NA 49445 XM_044309562.1 38 6 19 24 45 NA NA NA NA NA NA 49446 XM_029335294.2 20 25 23 8 0 NA NA NA NA NA NA 49447 XM_029342395.2 5258 2987 3073 5729 5655 Q3UZV7 0 Endosome/lysosome-associated apoptosis and autophagy regulator family member 2 (Estrogen-induced gene 121-like protein) Mus musculus (Mouse) negative regulation of nervous system development [GO:0051961]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of epidermis development [GO:0045684] GO:0005886; GO:0016020; GO:0030513; GO:0045684; GO:0051961; GO:0070700 49448 XM_029335566.2 247 91 149 165 273 Q8N5Y2 7.18e-49 Male-specific lethal 3 homolog (Male-specific lethal-3 homolog 1) (Male-specific lethal-3 protein-like 1) (MSL3-like 1) Homo sapiens (Human) chromatin organization [GO:0006325]; histone acetylation [GO:0016573]; histone deacetylation [GO:0016575]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; histone H4-K16 acetylation [GO:0043984]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA-templated transcription [GO:0006355]; regulation of dosage compensation by inactivation of X chromosome [GO:1900095] GO:0000123; GO:0003677; GO:0005634; GO:0005654; GO:0006325; GO:0006355; GO:0016573; GO:0016575; GO:0035064; GO:0035267; GO:0043967; GO:0043968; GO:0043984; GO:0045893; GO:0046972; GO:0072487; GO:1900095 49449 XM_044328522.1 82 0 57 215 182 Q9NVV5 4.45e-24 Androgen-induced gene 1 protein (AIG-1) (Fatty acid esters of hydroxy fatty acids hydrolase AIG1) (FAHFA hydrolase AIG1) (EC 3.1.-.-) Homo sapiens (Human) long-chain fatty acid catabolic process [GO:0042758] GO:0005886; GO:0012505; GO:0016020; GO:0016787; GO:0042758 49450 XM_044328522.1 82 0 57 215 182 Q9NVV5 4.45e-24 Androgen-induced gene 1 protein (AIG-1) (Fatty acid esters of hydroxy fatty acids hydrolase AIG1) (FAHFA hydrolase AIG1) (EC 3.1.-.-) Homo sapiens (Human) long-chain fatty acid catabolic process [GO:0042758] GO:0005886; GO:0012505; GO:0016020; GO:0016787; GO:0042758 49451 XM_044310424.1 0 183 0 0 0 NA NA NA NA NA NA 49452 XR_006396418.1 1246 813 522 1842 648 Q6V0K7 6.67e-30 Oncoprotein-induced transcript 3 protein (Liver-specific zona pellucida domain-containing protein) Rattus norvegicus (Rat) urate homeostasis [GO:1903118] GO:0005201; GO:0005509; GO:0005615; GO:0005635; GO:0009986; GO:1903118 49453 XR_006396418.1 1246 813 522 1842 648 Q6V0K7 6.67e-30 Oncoprotein-induced transcript 3 protein (Liver-specific zona pellucida domain-containing protein) Rattus norvegicus (Rat) urate homeostasis [GO:1903118] GO:0005201; GO:0005509; GO:0005615; GO:0005635; GO:0009986; GO:1903118 49454 XM_029330108.2 59 126 213 136 504 A7WM73 7.43e-41 Beta-hexosaminidase 1 (EC 3.2.1.52) (Beta-GlcNAcase 1) (Beta-N-acetylhexosaminidase 1) (Beta-hexosaminidase 2) (AtHEX2) (N-acetyl-beta-glucosaminidase 1) Arabidopsis thaliana (Mouse-ear cress) carbohydrate metabolic process [GO:0005975]; glycosaminoglycan metabolic process [GO:0030203] GO:0000325; GO:0004563; GO:0005773; GO:0005975; GO:0015929; GO:0016020; GO:0030203; GO:0099503; GO:0102148 49455 XR_006393457.1 17 4 15 48 39 NA NA NA NA NA NA 49456 XM_029346687.2 1060 1130 858 921 1231 NA NA NA NA NA NA 49457 XM_029345056.2 0 0 59 27 59 NA NA NA NA NA NA 49458 XM_044313972.1 0 7 0 0 1 NA NA NA NA NA NA 49459 XM_044320468.1 3371 1781 1610 2519 3042 NA NA NA NA NA NA 49460 XM_029354396.2 11 67 16 21 45 Q94K49 1.14e-22 Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1 (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) epigenetic regulation of gene expression [GO:0040029] GO:0003682; GO:0004518; GO:0005634; GO:0035098; GO:0035102; GO:0040029; GO:0046872 49461 XR_003823864.2 36 0 0 0 38 NA NA NA NA NA NA 49462 XM_044317171.1 183 194 100 350 113 NA NA NA NA NA NA 49463 XM_029352034.2 29 28 0 10 3 NA NA NA NA NA NA 49464 XM_044324648.1 3 10 8 11 2 NA NA NA NA NA NA 49465 XM_029357452.2 7 6 13 95 180 Q80TC6 0 Zinc finger SWIM domain-containing protein 5 Mus musculus (Mouse) NA GO:0008270; GO:0031462 49466 XR_006395841.1 94 0 37 0 0 Q15477 0 SKI2 subunit of superkiller complex protein (Helicase SKI2W) (Ski2) (EC 3.6.4.13) (Helicase-like protein) (HLP) Homo sapiens (Human) nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay [GO:0070478]; RNA catabolic process [GO:0006401] GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005829; GO:0006401; GO:0016887; GO:0055087; GO:0070478 49467 XM_029340660.2 585 428 421 490 193 P42891 1.78e-153 Endothelin-converting enzyme 1 (ECE-1) (EC 3.4.24.71) Bos taurus (Bovine) peptide hormone processing [GO:0016486]; protein processing [GO:0016485]; proteolysis [GO:0006508] GO:0004175; GO:0004222; GO:0005886; GO:0006508; GO:0016020; GO:0016485; GO:0016486; GO:0042803; GO:0046872 49468 XM_044316378.1 43 897 138 94 36 NA NA NA NA NA NA 49469 XR_006395475.1 0 0 0 44 38 NA NA NA NA NA NA 49470 XM_044326677.1 0 0 10 0 5 NA NA NA NA NA NA 49471 XM_029340762.2 0 154 71 0 0 P21674 8.05e-38 Follistatin (FS) (Activin-binding protein) Rattus norvegicus (Rat) ameloblast differentiation [GO:0036305]; BMP signaling pathway [GO:0030509]; cell differentiation [GO:0030154]; cellular response to growth factor stimulus [GO:0071363]; female gonad development [GO:0008585]; gamete generation [GO:0007276]; hair follicle morphogenesis [GO:0031069]; hematopoietic progenitor cell differentiation [GO:0002244]; keratinocyte proliferation [GO:0043616]; negative regulation of activin receptor signaling pathway [GO:0032926]; negative regulation of cell differentiation [GO:0045596]; negative regulation of epithelial cell differentiation [GO:0030857]; negative regulation of follicle-stimulating hormone secretion [GO:0046882]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis of dentin-containing tooth [GO:0042475]; pattern specification process [GO:0007389]; positive regulation of hair follicle development [GO:0051798]; regulation of BMP signaling pathway [GO:0030510]; response to organic cyclic compound [GO:0014070]; skeletal system development [GO:0001501] GO:0000122; GO:0001501; GO:0002244; GO:0005615; GO:0005634; GO:0005737; GO:0007276; GO:0007389; GO:0008585; GO:0014070; GO:0030154; GO:0030509; GO:0030510; GO:0030857; GO:0031069; GO:0032926; GO:0036305; GO:0038102; GO:0042475; GO:0043395; GO:0043616; GO:0045596; GO:0046882; GO:0048185; GO:0051798; GO:0071363 49472 XM_044319882.1 202 197 323 305 280 NA NA NA NA NA NA 49473 XM_029348182.2 83 42 60 188 185 Q9TUP7 2.72e-34 Orexin receptor type 2 (Ox-2-R) (Ox2-R) (Ox2R) (Hypocretin receptor type 2) Canis lupus familiaris (Dog) (Canis familiaris) circadian sleep/wake cycle process [GO:0022410]; feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; locomotion [GO:0040011]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; regulation of circadian sleep/wake cycle, wakefulness [GO:0010840]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0004930; GO:0005886; GO:0007186; GO:0007200; GO:0007218; GO:0007631; GO:0010840; GO:0016499; GO:0022410; GO:0040011; GO:0051480 49474 XM_029330265.2 24 19 34 7 14 Q5XGM3 1.89e-159 Betaine--homocysteine S-methyltransferase 1 (EC 2.1.1.5) Xenopus laevis (African clawed frog) amino-acid betaine catabolic process [GO:0006579]; methionine biosynthetic process [GO:0009086]; methylation [GO:0032259] GO:0005737; GO:0006579; GO:0008270; GO:0009086; GO:0032259; GO:0047150 49475 XM_029358095.2 6860 4863 5610 8155 6819 P51655 1.9e-83 Glypican-4 (K-glypican) [Cleaved into: Secreted glypican-4] Mus musculus (Mouse) cell migration [GO:0016477]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of presynapse assembly [GO:1905606]; regulation of protein localization to membrane [GO:1905475]; regulation of signal transduction [GO:0009966]; synaptic membrane adhesion [GO:0099560]; Wnt signaling pathway [GO:0016055] GO:0005615; GO:0005796; GO:0009897; GO:0009966; GO:0009986; GO:0016055; GO:0016477; GO:0042734; GO:0045202; GO:0062023; GO:0098696; GO:0098978; GO:0099560; GO:1905475; GO:1905606 49476 XM_044326404.1 0 0 0 27 25 P30975 2.43e-24 Tachykinin-like peptides receptor 99D (Tachykinin-like receptor at 99D) (dTKR) Drosophila melanogaster (Fruit fly) detection of chemical stimulus involved in sensory perception of smell [GO:0050911]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; neuropeptide signaling pathway [GO:0007218]; olfactory behavior [GO:0042048]; positive regulation of sensory perception of pain [GO:1904058]; tachykinin receptor signaling pathway [GO:0007217] GO:0004995; GO:0005886; GO:0007186; GO:0007217; GO:0007218; GO:0008188; GO:0016020; GO:0042048; GO:0050805; GO:0050911; GO:1904058 49477 XR_006392070.1 2 27 18 8 4 NA NA NA NA NA NA 49478 XM_044318630.1 663 374 609 600 1223 Q6TH47 2.95e-73 STAM-binding protein-like A (EC 3.4.19.-) Danio rerio (Zebrafish) (Brachydanio rerio) protein K63-linked deubiquitination [GO:0070536] GO:0005768; GO:0016020; GO:0032154; GO:0046872; GO:0061578; GO:0070536; GO:0140492 49479 XM_029351513.2 4370 2833 2407 4863 4458 Q75N73 3.38e-56 Metal cation symporter ZIP14 (Factor for adipocyte differentiation 123) (FAD-123) (Solute carrier family 39 member 14) (Zrt- and Irt-like protein 14) (ZIP-14) Mus musculus (Mouse) cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; cellular zinc ion homeostasis [GO:0006882]; chondrocyte differentiation [GO:0002062]; gluconeogenesis [GO:0006094]; import across plasma membrane [GO:0098739]; inorganic cation transmembrane transport [GO:0098662]; insulin receptor signaling pathway [GO:0008286]; iron import into cell [GO:0033212]; iron ion transmembrane transport [GO:0034755]; iron ion transport [GO:0006826]; manganese ion homeostasis [GO:0055071]; manganese ion transmembrane transport [GO:0071421]; negative regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051344]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; regulation of hormone levels [GO:0010817]; zinc ion import across plasma membrane [GO:0071578]; zinc ion transmembrane transport [GO:0071577]; zinc ion transport [GO:0006829] GO:0002062; GO:0005381; GO:0005384; GO:0005385; GO:0005765; GO:0005886; GO:0006094; GO:0006826; GO:0006829; GO:0006882; GO:0008286; GO:0010817; GO:0015086; GO:0015093; GO:0015296; GO:0016020; GO:0016323; GO:0016324; GO:0031901; GO:0031902; GO:0032869; GO:0033212; GO:0034755; GO:0045745; GO:0051344; GO:0055071; GO:0071333; GO:0071421; GO:0071577; GO:0071578; GO:0098662; GO:0098739 49480 XM_029345177.2 233 178 117 263 186 NA NA NA NA NA NA 49481 XR_006391680.1 48 36 17 18 53 NA NA NA NA NA NA 49482 XM_044313096.1 113 214 109 305 273 NA NA NA NA NA NA 49483 XM_029343762.2 130 69 92 104 332 NA NA NA NA NA NA 49484 XM_029345779.2 611 647 670 606 878 Q0DXS3 1.58e-137 Probable RNA-dependent RNA polymerase 1 (OsRDR1) (EC 2.7.7.48) Oryza sativa subsp. japonica (Rice) positive regulation of post-transcriptional gene silencing [GO:0060148]; response to salicylic acid [GO:0009751]; response to virus [GO:0009615]; siRNA processing [GO:0030422]; wax biosynthetic process [GO:0010025] GO:0003723; GO:0003968; GO:0009615; GO:0009751; GO:0010025; GO:0030422; GO:0031380; GO:0060148 49485 XM_029335316.2 192 1349 1774 913 878 Q3US41 2.85e-134 Epithelial splicing regulatory protein 1 (RNA-binding motif protein 35A) (RNA-binding protein 35A) Mus musculus (Mouse) alternative mRNA splicing, via spliceosome [GO:0000380]; branching involved in salivary gland morphogenesis [GO:0060445]; epithelial cell proliferation [GO:0050673]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; positive regulation of epithelial cell proliferation [GO:0050679]; regulation of inner ear auditory receptor cell fate specification [GO:0042669]; regulation of RNA splicing [GO:0043484] GO:0000380; GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0016604; GO:0042669; GO:0043484; GO:0050673; GO:0050679; GO:0060441; GO:0060445; GO:1990904 49486 XM_044316636.1 2101 2078 0 679 742 NA NA NA NA NA NA 49487 XM_029345438.2 223 289 111 311 143 Q02978 1.29e-152 Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP) (alpha-oxoglutarate carrier) (Solute carrier family 25 member 11) (SLC25A11) Homo sapiens (Human) gluconeogenesis [GO:0006094]; lipid transport [GO:0006869]; malate transmembrane transport [GO:0071423]; oxaloacetate transport [GO:0015729]; phosphate ion transmembrane transport [GO:0035435]; succinate transmembrane transport [GO:0071422]; sulfate transport [GO:0008272]; thiosulfate transport [GO:0015709] GO:0003723; GO:0005634; GO:0005739; GO:0005743; GO:0005886; GO:0006094; GO:0006869; GO:0008272; GO:0015116; GO:0015117; GO:0015131; GO:0015140; GO:0015141; GO:0015297; GO:0015367; GO:0015709; GO:0015729; GO:0022857; GO:0035435; GO:0071422; GO:0071423 49488 XM_044307563.1 0 513 0 0 428 P23790 5.03e-64 Serum response factor (SRF) Xenopus laevis (African clawed frog) actin cytoskeleton organization [GO:0030036]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000981; GO:0003700; GO:0005634; GO:0010736; GO:0030036; GO:0045944; GO:0046983 49489 XR_006392220.1 552 160 165 551 263 NA NA NA NA NA NA 49490 XM_044321542.1 3021 1432 1279 2740 1562 Q6IP59 8.7e-149 Choline transporter-like protein 2 (Solute carrier family 44 member 2) Xenopus laevis (African clawed frog) NA GO:0016020; GO:0022857 49491 XM_029331177.2 25 0 37 50 0 P23416 2.56e-84 Glycine receptor subunit alpha-2 Homo sapiens (Human) cellular response to amino acid stimulus [GO:0071230]; cellular response to ethanol [GO:0071361]; cellular response to zinc ion [GO:0071294]; chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; neuropeptide signaling pathway [GO:0007218]; regulation of membrane potential [GO:0042391]; response to amino acid [GO:0043200]; signal transduction [GO:0007165]; synaptic transmission, glycinergic [GO:0060012] GO:0004888; GO:0005231; GO:0005886; GO:0007165; GO:0007218; GO:0007268; GO:0016594; GO:0016934; GO:0022852; GO:0030594; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0043200; GO:0045202; GO:0045211; GO:0046872; GO:0050877; GO:0060012; GO:0071230; GO:0071294; GO:0071361; GO:0098690; GO:1902476; GO:1904315 49492 XM_029352757.1 0 2 2 3 15 NA NA NA NA NA NA 49493 XM_044308168.1 0 11 0 0 0 P16066 6.42e-66 Atrial natriuretic peptide receptor 1 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type A) (ANP-A) (ANPR-A) (NPR-A) (Guanylate cyclase A) (GC-A) Homo sapiens (Human) blood vessel diameter maintenance [GO:0097746]; body fluid secretion [GO:0007589]; cell surface receptor signaling pathway [GO:0007166]; cGMP biosynthetic process [GO:0006182]; cGMP-mediated signaling [GO:0019934]; dopamine metabolic process [GO:0042417]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell growth [GO:0030308]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of cGMP-mediated signaling [GO:0010753]; positive regulation of renal sodium excretion [GO:0035815]; positive regulation of urine volume [GO:0035810]; protein phosphorylation [GO:0006468]; receptor guanylyl cyclase signaling pathway [GO:0007168]; regulation of blood pressure [GO:0008217]; regulation of vascular permeability [GO:0043114]; signal transduction [GO:0007165] GO:0001653; GO:0004383; GO:0004672; GO:0005524; GO:0005525; GO:0005886; GO:0006182; GO:0006468; GO:0007165; GO:0007166; GO:0007168; GO:0007589; GO:0008217; GO:0008528; GO:0010753; GO:0016525; GO:0016941; GO:0017046; GO:0019934; GO:0030308; GO:0035810; GO:0035815; GO:0042417; GO:0042562; GO:0043114; GO:0043235; GO:0048662; GO:0097746; GO:1990620 49494 XM_029332221.2 425 147 19 589 337 NA NA NA NA NA NA 49495 XR_006392202.1 131 84 73 85 96 NA NA NA NA NA NA 49496 XR_006393188.1 38 47 57 21 187 NA NA NA NA NA NA 49497 XM_044309638.1 1512 1071 1097 907 2111 Q9NBX4 7.41e-27 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 49498 XM_044313792.1 0 0 0 0 9 Q09575 4.58e-30 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 49499 XM_044313792.1 0 0 0 0 9 Q09575 4.58e-30 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 49500 XM_029350267.2 51 36 33 48 30 Q8IS64 1.44e-151 Endothelin-converting enzyme homolog (ECE) (EC 3.4.24.-) Locusta migratoria (Migratory locust) proteolysis [GO:0006508] GO:0004175; GO:0004222; GO:0005886; GO:0006508; GO:0008270 49501 XM_044326035.1 1069 949 969 780 1702 Q9NSN8 5.29e-79 Gamma-1-syntrophin (G1SYN) (Syntrophin-4) (SYN4) Homo sapiens (Human) cell communication [GO:0007154] GO:0003779; GO:0005198; GO:0005634; GO:0005737; GO:0005856; GO:0007154; GO:0008022; GO:0016010; GO:0016013; GO:0032587 49502 XM_044320404.1 66 141 30 66 1 NA NA NA NA NA NA 49503 XM_029331426.2 0 0 3 0 18 NA NA NA NA NA NA 49504 XR_006391551.1 145 43 69 25 86 NA NA NA NA NA NA 49505 XM_044320902.1 7 43 0 0 7 Q9K7A0 3.8e-30 Probable cysteine desulfurase (EC 2.8.1.7) Halalkalibacterium halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) (Bacillus halodurans) cysteine metabolic process [GO:0006534] GO:0006534; GO:0030170; GO:0031071 49506 XM_029329231.2 389 322 223 407 435 P29054 2.88e-158 Transcription initiation factor IIB (EC 2.3.1.48) (General transcription factor TFIIB) Xenopus laevis (African clawed frog) protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription by RNA polymerase II [GO:0006366]; transcription initiation at RNA polymerase II promoter [GO:0006367]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; viral transcription [GO:0019083] GO:0000979; GO:0000993; GO:0001174; GO:0004402; GO:0005634; GO:0005694; GO:0006366; GO:0006367; GO:0006473; GO:0008270; GO:0016407; GO:0017025; GO:0019083; GO:0032993; GO:0051123; GO:1990114; GO:1990841 49507 XM_044307678.1 0 0 255 138 325 Q8IVE3 0 Pleckstrin homology domain-containing family H member 2 Homo sapiens (Human) negative regulation of actin filament depolymerization [GO:0030835] GO:0003779; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0016604; GO:0030027; GO:0030835; GO:0030864 49508 XR_006397075.1 21 82 15 29 128 NA NA NA NA NA NA 49509 XM_029336276.2 27 18 23 32 42 P34147 8.35e-150 Rho-related protein racA Dictyostelium discoideum (Social amoeba) actin filament organization [GO:0007015]; cortical cytoskeleton organization [GO:0030865]; establishment or maintenance of cell polarity [GO:0007163]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; response to bacterium [GO:0009617]; small GTPase mediated signal transduction [GO:0007264] GO:0003924; GO:0005525; GO:0005856; GO:0005886; GO:0005938; GO:0007015; GO:0007163; GO:0007264; GO:0008360; GO:0009617; GO:0019901; GO:0030865; GO:0031410; GO:0032956; GO:0042995 49510 XM_029330243.2 299 117 91 69 370 NA NA NA NA NA NA 49511 XM_029329582.2 33 0 7 3 12 Q01603 6.21e-89 Peroxidase (DmPO) (EC 1.11.1.7) (Chorion peroxidase) Drosophila melanogaster (Fruit fly) egg chorion assembly [GO:0007306]; hydrogen peroxide catabolic process [GO:0042744]; peptide cross-linking [GO:0018149]; peptidyl-tyrosine modification [GO:0018212]; response to oxidative stress [GO:0006979] GO:0004601; GO:0005576; GO:0006979; GO:0007306; GO:0018149; GO:0018212; GO:0020037; GO:0042600; GO:0042744; GO:0046872; GO:0140825 49512 XM_044319773.1 206 71 195 108 157 Q3US41 2.48e-132 Epithelial splicing regulatory protein 1 (RNA-binding motif protein 35A) (RNA-binding protein 35A) Mus musculus (Mouse) alternative mRNA splicing, via spliceosome [GO:0000380]; branching involved in salivary gland morphogenesis [GO:0060445]; epithelial cell proliferation [GO:0050673]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; positive regulation of epithelial cell proliferation [GO:0050679]; regulation of inner ear auditory receptor cell fate specification [GO:0042669]; regulation of RNA splicing [GO:0043484] GO:0000380; GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0016604; GO:0042669; GO:0043484; GO:0050673; GO:0050679; GO:0060441; GO:0060445; GO:1990904 49513 XM_029331309.2 59 2 25 0 95 NA NA NA NA NA NA 49514 XM_029345806.2 73 38 59 96 159 NA NA NA NA NA NA 49515 XM_044327236.1 86 0 154 0 59 NA NA NA NA NA NA 49516 XM_029346712.2 62 19 173 0 97 Q5I020 2.09e-69 Proton-coupled zinc antiporter SLC30A8 (Solute carrier family 30 member 8) (Zinc transporter 8) (ZnT-8) Xenopus laevis (African clawed frog) zinc ion import into organelle [GO:0062111] GO:0005886; GO:0030658; GO:0030667; GO:0046872; GO:0062111; GO:0140826 49517 XM_029333569.2 15 18 14 26 33 Q4R4R9 1.23e-66 Ras-related protein Rab-3A Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) exocytosis [GO:0006887]; protein transport [GO:0015031] GO:0003924; GO:0005525; GO:0005764; GO:0005829; GO:0005886; GO:0006887; GO:0015031; GO:0030133; GO:0030424; GO:0048786; GO:0098793; GO:0098794 49518 XM_029327067.2 230 215 141 312 289 Q7TN31 5.4e-60 Angiogenic factor with G patch and FHA domains 1 (Angiogenic factor VG5Q) (mVG5Q) Mus musculus (Mouse) angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; positive regulation of angiogenesis [GO:0045766]; positive regulation of endothelial cell proliferation [GO:0001938] GO:0001525; GO:0001938; GO:0003676; GO:0005576; GO:0005737; GO:0007155; GO:0030154; GO:0045766; GO:0048471 49519 XM_029349593.2 2840 4064 2962 4050 2840 Q8WNR0 6.41e-23 High affinity copper uptake protein 1 (Copper transporter 1) (CTR1) (Solute carrier family 31 member 1) Sus scrofa (Pig) cellular copper ion homeostasis [GO:0006878]; copper ion import [GO:0015677]; establishment of localization in cell [GO:0051649] GO:0005375; GO:0005770; GO:0005886; GO:0006878; GO:0014704; GO:0015677; GO:0042802; GO:0051649; GO:0055037 49520 XM_029326040.2 14 0 30 0 6 Q96MB7 7.96e-25 Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease) Homo sapiens (Human) NA GO:0004518; GO:0005634; GO:0005829; GO:0005886; GO:0034451; GO:0046872 49521 XM_029357157.2 806 652 405 815 433 Q8K0V4 6.59e-97 CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3) Mus musculus (Mouse) negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; positive regulation of cold-induced thermogenesis [GO:0120162]; regulation of DNA-templated transcription [GO:0006355]; regulation of stem cell population maintenance [GO:2000036]; RNA-mediated gene silencing [GO:0031047]; trophectodermal cell differentiation [GO:0001829] GO:0000289; GO:0000932; GO:0001829; GO:0005634; GO:0006355; GO:0030014; GO:0030015; GO:0031047; GO:0033147; GO:0120162; GO:2000036 49522 XM_029357157.2 806 652 405 815 433 Q8K0V4 1.96e-72 CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3) Mus musculus (Mouse) negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; positive regulation of cold-induced thermogenesis [GO:0120162]; regulation of DNA-templated transcription [GO:0006355]; regulation of stem cell population maintenance [GO:2000036]; RNA-mediated gene silencing [GO:0031047]; trophectodermal cell differentiation [GO:0001829] GO:0000289; GO:0000932; GO:0001829; GO:0005634; GO:0006355; GO:0030014; GO:0030015; GO:0031047; GO:0033147; GO:0120162; GO:2000036 49523 XR_003826863.2 1839 2336 1046 1284 1016 NA NA NA NA NA NA 49524 XM_044326563.1 12 8 0 24 1 NA NA NA NA NA NA 49525 XM_044315628.1 0 7 38 0 214 NA NA NA NA NA NA 49526 XM_044322818.1 3 2 11 0 12 NA NA NA NA NA NA 49527 XR_006391365.1 174 311 56 142 81 NA NA NA NA NA NA 49528 XM_029333060.2 0 0 0 171 0 Q6UXP7 4.55e-60 Protein FAM151B Homo sapiens (Human) NA GO:0005615 49529 XM_044317003.1 6 0 8 3 76 NA NA NA NA NA NA 49530 XM_044322850.1 886 536 0 595 356 Q5U584 2.98e-58 SH3 domain-binding protein 5-like (SH3BP-5-like) Xenopus laevis (African clawed frog) intracellular signal transduction [GO:0035556] GO:0005085; GO:0035556 49531 XR_003824801.2 41 69 45 90 57 NA NA NA NA NA NA 49532 XM_029326106.2 65 25 20 54 43 Q9ET47 1.02e-31 Espin (Ectoplasmic specialization protein) Mus musculus (Mouse) actin filament bundle assembly [GO:0051017]; actin filament network formation [GO:0051639]; locomotory behavior [GO:0007626]; microvillar actin bundle assembly [GO:0030034]; negative regulation of cytoskeleton organization [GO:0051494]; parallel actin filament bundle assembly [GO:0030046]; positive regulation of filopodium assembly [GO:0051491]; sensory perception of sound [GO:0007605] GO:0005737; GO:0005829; GO:0005902; GO:0005903; GO:0007605; GO:0007626; GO:0015629; GO:0017124; GO:0030034; GO:0030046; GO:0031941; GO:0032420; GO:0032421; GO:0032426; GO:0043197; GO:0051015; GO:0051017; GO:0051491; GO:0051494; GO:0051639; GO:0070161 49533 XM_029326106.2 65 25 20 54 43 Q9ET47 5.53e-28 Espin (Ectoplasmic specialization protein) Mus musculus (Mouse) actin filament bundle assembly [GO:0051017]; actin filament network formation [GO:0051639]; locomotory behavior [GO:0007626]; microvillar actin bundle assembly [GO:0030034]; negative regulation of cytoskeleton organization [GO:0051494]; parallel actin filament bundle assembly [GO:0030046]; positive regulation of filopodium assembly [GO:0051491]; sensory perception of sound [GO:0007605] GO:0005737; GO:0005829; GO:0005902; GO:0005903; GO:0007605; GO:0007626; GO:0015629; GO:0017124; GO:0030034; GO:0030046; GO:0031941; GO:0032420; GO:0032421; GO:0032426; GO:0043197; GO:0051015; GO:0051017; GO:0051491; GO:0051494; GO:0051639; GO:0070161 49534 XM_029326106.2 65 25 20 54 43 Q9ET47 7.79e-22 Espin (Ectoplasmic specialization protein) Mus musculus (Mouse) actin filament bundle assembly [GO:0051017]; actin filament network formation [GO:0051639]; locomotory behavior [GO:0007626]; microvillar actin bundle assembly [GO:0030034]; negative regulation of cytoskeleton organization [GO:0051494]; parallel actin filament bundle assembly [GO:0030046]; positive regulation of filopodium assembly [GO:0051491]; sensory perception of sound [GO:0007605] GO:0005737; GO:0005829; GO:0005902; GO:0005903; GO:0007605; GO:0007626; GO:0015629; GO:0017124; GO:0030034; GO:0030046; GO:0031941; GO:0032420; GO:0032421; GO:0032426; GO:0043197; GO:0051015; GO:0051017; GO:0051491; GO:0051494; GO:0051639; GO:0070161 49535 XM_044325122.1 5 1 15 13 104 B8VIU6 1.13e-56 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 49536 XM_044325122.1 5 1 15 13 104 B8VIU6 1.59e-53 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 49537 XM_044310432.1 25 25 6 35 44 NA NA NA NA NA NA 49538 XR_003826755.2 72 29 26 98 56 NA NA NA NA NA NA 49539 XM_029323473.2 9 1 0 0 14 NA NA NA NA NA NA 49540 XM_044325239.1 280 299 239 38 75 NA NA NA NA NA NA 49541 XR_006395921.1 2 60 20 9 9 NA NA NA NA NA NA 49542 XR_006396644.1 17 26 49 0 27 NA NA NA NA NA NA 49543 XM_029334410.2 1035 800 645 1206 938 Q9XSC3 0 WD repeat-containing protein 44 (Rab11-binding protein) (Rabphilin-11) Bos taurus (Bovine) NA GO:0005794; GO:0005829; GO:0010008; GO:0048471 49544 XM_029332555.2 229 106 95 211 148 Q8R0F3 2.88e-152 Formylglycine-generating enzyme (FGE) (EC 1.8.3.7) (C-alpha-formylglycine-generating enzyme 1) (Sulfatase-modifying factor 1) Mus musculus (Mouse) post-translational protein modification [GO:0043687]; protein oxidation [GO:0018158] GO:0005783; GO:0005788; GO:0018158; GO:0042802; GO:0043687; GO:0120147; GO:1903135 49545 XM_029352531.2 309 372 102 225 252 NA NA NA NA NA NA 49546 XR_003828235.2 122 138 75 168 46 NA NA NA NA NA NA 49547 XR_006393744.1 26 16 39 31 193 NA NA NA NA NA NA 49548 XR_006395626.1 0 1 0 6 3 NA NA NA NA NA NA 49549 XM_029340661.2 497 882 737 1001 588 Q4PZA2 4.9e-155 Endothelin-converting enzyme 1 (ECE-1) (EC 3.4.24.71) Mus musculus (Mouse) apoptotic process [GO:0006915]; axonogenesis involved in innervation [GO:0060385]; blood vessel diameter maintenance [GO:0097746]; bradykinin catabolic process [GO:0010815]; calcitonin catabolic process [GO:0010816]; ear development [GO:0043583]; embryonic digit morphogenesis [GO:0042733]; embryonic heart tube development [GO:0035050]; endothelin maturation [GO:0034959]; gene expression [GO:0010467]; heart development [GO:0007507]; hormone catabolic process [GO:0042447]; neuron projection development [GO:0031175]; peptide hormone processing [GO:0016486]; pharyngeal system development [GO:0060037]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of receptor recycling [GO:0001921]; protein processing [GO:0016485]; regulation of blood pressure [GO:0008217]; regulation of ERK1 and ERK2 cascade [GO:0070372]; response to hypoxia [GO:0001666]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; substance P catabolic process [GO:0010814]; sympathetic neuron axon guidance [GO:0097492] GO:0001666; GO:0001921; GO:0004175; GO:0004222; GO:0005768; GO:0005769; GO:0005794; GO:0005886; GO:0006915; GO:0007507; GO:0008217; GO:0008270; GO:0009897; GO:0009986; GO:0010467; GO:0010613; GO:0010814; GO:0010815; GO:0010816; GO:0016020; GO:0016485; GO:0016486; GO:0030141; GO:0031175; GO:0031410; GO:0031982; GO:0033093; GO:0034959; GO:0035050; GO:0042447; GO:0042733; GO:0042802; GO:0042803; GO:0043583; GO:0043950; GO:0045745; GO:0048471; GO:0060037; GO:0060385; GO:0070372; GO:0097492; GO:0097746; GO:1902287 49550 XM_029351839.2 6368 7113 2211 6593 10237 P61210 1.19e-118 ADP-ribosylation factor 1 (EC 3.6.5.2) (lARF1) Locusta migratoria (Migratory locust) establishment of localization in cell [GO:0051649]; protein transport [GO:0015031]; system development [GO:0048731]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0003924; GO:0005525; GO:0015031; GO:0016192; GO:0048731; GO:0051649 49551 XR_006393277.1 61 155 19 52 74 NA NA NA NA NA NA 49552 XM_029327507.2 0 39 3 21 20 NA NA NA NA NA NA 49553 XM_044325009.1 12 1 21 8 39 P19491 1.72e-85 Glutamate receptor 2 (GluR-2) (AMPA-selective glutamate receptor 2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (GluA2) Rattus norvegicus (Rat) cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to glycine [GO:1905430]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226] GO:0000149; GO:0001540; GO:0001919; GO:0004970; GO:0004971; GO:0005234; GO:0005783; GO:0005789; GO:0005886; GO:0007268; GO:0008021; GO:0008092; GO:0008328; GO:0009986; GO:0010226; GO:0014069; GO:0015276; GO:0015277; GO:0016020; GO:0019865; GO:0019901; GO:0021987; GO:0030165; GO:0030424; GO:0030425; GO:0030426; GO:0030672; GO:0031623; GO:0032279; GO:0032281; GO:0032590; GO:0032839; GO:0032991; GO:0035235; GO:0035254; GO:0035255; GO:0036477; GO:0038023; GO:0042734; GO:0042802; GO:0043005; GO:0043025; GO:0043195; GO:0043197; GO:0043198; GO:0043204; GO:0044326; GO:0044327; GO:0045184; GO:0045202; GO:0045211; GO:0048787; GO:0050806; GO:0051117; GO:0051262; GO:0051966; GO:0060992; GO:0097060; GO:0097110; GO:0098685; GO:0098793; GO:0098839; GO:0098978; GO:0099507; GO:0099544; GO:0106033; GO:1904315; GO:1905430; GO:1990416 49554 XM_044318264.1 9 0 83 10 18 P31422 0 Metabotropic glutamate receptor 3 (mGluR3) Rattus norvegicus (Rat) G protein-coupled glutamate receptor signaling pathway [GO:0007216]; gene expression [GO:0010467]; modulation of chemical synaptic transmission [GO:0050804]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; regulation of synaptic transmission, glutamatergic [GO:0051966]; sensory perception of pain [GO:0019233] GO:0001640; GO:0001641; GO:0005246; GO:0005886; GO:0007216; GO:0010467; GO:0014069; GO:0019233; GO:0030424; GO:0042734; GO:0043005; GO:0043197; GO:0045211; GO:0050804; GO:0051966; GO:0097110; GO:0097449; GO:0098794; GO:0098978; GO:0099170 49555 XM_029334682.2 3901 3306 2333 3811 3632 O14490 3.38e-23 Disks large-associated protein 1 (DAP-1) (Guanylate kinase-associated protein) (hGKAP) (PSD-95/SAP90-binding protein 1) (SAP90/PSD-95-associated protein 1) (SAPAP1) Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962] GO:0005886; GO:0007268; GO:0014069; GO:0044877; GO:0060090; GO:0098962; GO:0098978; GO:0099572 49556 XM_044318776.1 0 0 0 0 31 Q8R0G9 4.03e-178 Nuclear pore complex protein Nup133 (133 kDa nucleoporin) (Nucleoporin Nup133) Mus musculus (Mouse) mRNA export from nucleus [GO:0006406]; nephron development [GO:0072006]; neural tube development [GO:0021915]; neurogenesis [GO:0022008]; nuclear pore organization [GO:0006999]; nucleocytoplasmic transport [GO:0006913]; paraxial mesoderm development [GO:0048339]; poly(A)+ mRNA export from nucleus [GO:0016973]; protein import into nucleus [GO:0006606]; somite development [GO:0061053]; transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000972] GO:0000776; GO:0000940; GO:0000972; GO:0005635; GO:0005643; GO:0006406; GO:0006606; GO:0006913; GO:0006999; GO:0016973; GO:0017056; GO:0021915; GO:0022008; GO:0031080; GO:0031965; GO:0048339; GO:0061053; GO:0072006 49557 XM_029350860.2 673 114 1 431 99 Q6VFT6 7.4e-54 Forkhead box protein L2 Sus scrofa (Pig) anatomical structure morphogenesis [GO:0009653]; apoptotic DNA fragmentation [GO:0006309]; cell differentiation [GO:0030154]; embryonic eye morphogenesis [GO:0048048]; extraocular skeletal muscle development [GO:0002074]; female somatic sex determination [GO:0019101]; granulosa cell differentiation [GO:0060014]; ovarian follicle development [GO:0001541]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0001541; GO:0002074; GO:0003677; GO:0003700; GO:0005634; GO:0006309; GO:0006357; GO:0009653; GO:0019101; GO:0030154; GO:0043028; GO:0043065; GO:0043280; GO:0045893; GO:0045944; GO:0048048; GO:0060014 49558 XR_006392857.1 0 1 0 8 16 NA NA NA NA NA NA 49559 XR_003825765.2 84 3 31 30 8 NA NA NA NA NA NA 49560 XM_044309859.1 1315 2437 1163 2187 7442 NA NA NA NA NA NA 49561 XM_029341680.2 5200 3898 4788 5494 3011 O57321 1.34e-129 Excitatory amino acid transporter 1 (SEAAT1) (Sodium-dependent glutamate/aspartate transporter) (GLAST) Ambystoma tigrinum (Eastern tiger salamander) chloride transmembrane transport [GO:1902476]; D-aspartate import across plasma membrane [GO:0070779]; L-aspartate import across plasma membrane [GO:0140009]; L-glutamate import across plasma membrane [GO:0098712]; potassium ion transmembrane transport [GO:0071805] GO:0005314; GO:0005886; GO:0015501; GO:0046872; GO:0070779; GO:0071805; GO:0098712; GO:0140009; GO:1902476 49562 XM_044308389.1 564 507 299 334 418 A1L3P4 1.86e-179 Sodium/hydrogen exchanger 6 (Na(+)/H(+) exchanger 6) (NHE-6) (Sodium/hydrogen exchanger) (Solute carrier family 9 member 6) Mus musculus (Mouse) axon extension [GO:0048675]; brain-derived neurotrophic factor receptor signaling pathway [GO:0031547]; dendrite extension [GO:0097484]; dendritic spine development [GO:0060996]; establishment of cell polarity [GO:0030010]; neuron projection morphogenesis [GO:0048812]; potassium ion transmembrane transport [GO:0071805]; proton transmembrane transport [GO:1902600]; regulation of intracellular pH [GO:0051453]; regulation of neurotrophin TRK receptor signaling pathway [GO:0051386]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; sodium ion import across plasma membrane [GO:0098719]; synapse organization [GO:0050808] GO:0005739; GO:0005768; GO:0005769; GO:0005770; GO:0005789; GO:0005886; GO:0015385; GO:0015386; GO:0030010; GO:0030425; GO:0031410; GO:0031547; GO:0031901; GO:0043231; GO:0043679; GO:0044308; GO:0045202; GO:0048675; GO:0048812; GO:0050808; GO:0051386; GO:0051453; GO:0055037; GO:0055038; GO:0060996; GO:0071805; GO:0097484; GO:0098685; GO:0098719; GO:0098978; GO:0099072; GO:1902600 49563 XM_029334509.2 1379 940 898 1438 1755 Q5ZJH7 2.05e-59 Protein CNPPD1 Gallus gallus (Chicken) regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079] GO:0000079; GO:0016020; GO:0019901 49564 XM_044319211.1 53 41 85 74 15 O55131 7.88e-164 Septin-7 (CDC10 protein homolog) Mus musculus (Mouse) cilium assembly [GO:0060271]; collateral sprouting [GO:0048668]; cortical cytoskeleton organization [GO:0030865]; cytoskeleton-dependent cytokinesis [GO:0061640]; dendritic spine morphogenesis [GO:0060997]; mitotic cytokinesis [GO:0000281]; positive regulation of non-motile cilium assembly [GO:1902857]; postsynapse organization [GO:0099173]; pseudopodium retraction [GO:0031270]; regulation of embryonic cell shape [GO:0016476]; spermatogenesis [GO:0007283] GO:0000281; GO:0000776; GO:0001725; GO:0003924; GO:0005525; GO:0005634; GO:0005819; GO:0005930; GO:0005938; GO:0005940; GO:0007283; GO:0015630; GO:0016020; GO:0016476; GO:0030496; GO:0030865; GO:0031105; GO:0031270; GO:0032153; GO:0032154; GO:0032156; GO:0032160; GO:0032991; GO:0042734; GO:0042802; GO:0043005; GO:0043025; GO:0043209; GO:0043679; GO:0045202; GO:0048668; GO:0060090; GO:0060271; GO:0060997; GO:0061640; GO:0097227; GO:0097730; GO:0098978; GO:0099173; GO:0099186; GO:0150050; GO:1902857 49565 XM_044323959.1 10 2 10 11 21 P06803 1.69e-52 Serine/threonine-protein kinase pim-1 (EC 2.7.11.1) Mus musculus (Mouse) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cellular detoxification [GO:1990748]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cardioblast proliferation [GO:1905062]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of transmembrane transporter activity [GO:0022898]; vitamin D receptor signaling pathway [GO:0070561] GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0005886; GO:0006468; GO:0006915; GO:0007049; GO:0022898; GO:0030145; GO:0043024; GO:0043066; GO:0043433; GO:0043539; GO:0045737; GO:0045893; GO:0046777; GO:0050821; GO:0060045; GO:0070561; GO:0071902; GO:0090336; GO:0106310; GO:1902033; GO:1905062; GO:1990748 49566 XM_029339592.2 196 82 168 169 134 NA NA NA NA NA NA 49567 XM_044328990.1 97 6 18 43 17 NA NA NA NA NA NA 49568 XR_003822956.2 212 202 114 128 119 NA NA NA NA NA NA 49569 XM_044324474.1 26 0 56 70 166 NA NA NA NA NA NA 49570 XR_006395459.1 5 8 0 4 14 NA NA NA NA NA NA 49571 XM_029333768.2 226 129 109 104 221 Q99816 3.33e-24 Tumor susceptibility gene 101 protein (ESCRT-I complex subunit TSG101) Homo sapiens (Human) autophagosome maturation [GO:0097352]; cell cycle [GO:0007049]; cell division [GO:0051301]; endosome to lysosome transport [GO:0008333]; exosomal secretion [GO:1990182]; extracellular transport [GO:0006858]; keratinocyte differentiation [GO:0030216]; macroautophagy [GO:0016236]; membrane fission [GO:0090148]; multivesicular body assembly [GO:0036258]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of ubiquitin-dependent endocytosis [GO:2000397]; positive regulation of viral budding via host ESCRT complex [GO:1903774]; protein monoubiquitination [GO:0006513]; protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]; regulation of cell cycle [GO:0051726]; regulation of cell growth [GO:0001558]; regulation of extracellular exosome assembly [GO:1903551]; regulation of MAP kinase activity [GO:0043405]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; viral budding [GO:0046755]; viral budding via host ESCRT complex [GO:0039702]; viral release from host cell [GO:0019076] GO:0000122; GO:0000813; GO:0001558; GO:0003677; GO:0003714; GO:0005730; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005771; GO:0005815; GO:0005829; GO:0005886; GO:0006513; GO:0006858; GO:0007049; GO:0007175; GO:0008285; GO:0008333; GO:0010008; GO:0016236; GO:0019076; GO:0030216; GO:0030374; GO:0031625; GO:0031901; GO:0031902; GO:0036258; GO:0039702; GO:0042059; GO:0042803; GO:0043130; GO:0043162; GO:0043328; GO:0043405; GO:0044877; GO:0046755; GO:0046790; GO:0048306; GO:0051301; GO:0051726; GO:0070062; GO:0090148; GO:0090543; GO:0097352; GO:1903543; GO:1903551; GO:1903774; GO:1990182; GO:2000397 49572 XM_044307880.1 79 78 19 44 58 Q96AY4 2.51e-158 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 49573 XM_044307880.1 79 78 19 44 58 Q96AY4 1.28e-112 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 49574 XM_044307880.1 79 78 19 44 58 Q96AY4 1.42e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 49575 XM_044312671.1 0 26 0 19 0 Q8CGE9 4.74e-28 Regulator of G-protein signaling 12 (RGS12) Mus musculus (Mouse) regulation of G protein-coupled receptor signaling pathway [GO:0008277]; signal transduction [GO:0007165]; termination of G protein-coupled receptor signaling pathway [GO:0038032] GO:0001965; GO:0005096; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0005886; GO:0007165; GO:0008277; GO:0030425; GO:0030695; GO:0032991; GO:0038032; GO:0043025; GO:0045202; GO:0097440 49576 XM_044312671.1 0 26 0 19 0 Q8CGE9 6.4e-27 Regulator of G-protein signaling 12 (RGS12) Mus musculus (Mouse) regulation of G protein-coupled receptor signaling pathway [GO:0008277]; signal transduction [GO:0007165]; termination of G protein-coupled receptor signaling pathway [GO:0038032] GO:0001965; GO:0005096; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0005886; GO:0007165; GO:0008277; GO:0030425; GO:0030695; GO:0032991; GO:0038032; GO:0043025; GO:0045202; GO:0097440 49577 XM_044308050.1 0 0 14 0 19 B3EWZ3 6.14e-94 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 49578 XM_044308050.1 0 0 14 0 19 B3EWZ3 2.75e-86 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 49579 XM_044308050.1 0 0 14 0 19 B3EWZ3 1.02e-74 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 49580 XM_044308050.1 0 0 14 0 19 B3EWZ3 1.03e-70 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 49581 XM_044308050.1 0 0 14 0 19 B3EWZ3 4.14e-69 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 49582 XM_044308050.1 0 0 14 0 19 B3EWZ3 1.44e-60 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 49583 XM_044308050.1 0 0 14 0 19 B3EWZ3 2.56e-54 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 49584 XM_029329155.2 120 78 31 103 97 Q8TB37 1.54e-104 Iron-sulfur protein NUBPL (IND1 homolog) (Nucleotide-binding protein-like) (huInd1) Homo sapiens (Human) iron-sulfur cluster assembly [GO:0016226]; mitochondrial respiratory chain complex I assembly [GO:0032981]; mitochondrion morphogenesis [GO:0070584] GO:0005524; GO:0005739; GO:0005759; GO:0005886; GO:0016226; GO:0032981; GO:0046872; GO:0051539; GO:0070584; GO:0140663 49585 XM_044323576.1 6 0 3 0 24 NA NA NA NA NA NA 49586 XM_044327732.1 0 10 1 299 120 NA NA NA NA NA NA 49587 XM_029333859.2 205 82 26 86 151 NA NA NA NA NA NA 49588 XM_029324129.2 500 402 190 1128 551 NA NA NA NA NA NA 49589 XM_029330242.2 0 0 19 0 0 NA NA NA NA NA NA 49590 XM_029336335.2 2500 2112 1443 1581 1505 NA NA NA NA NA NA 49591 XM_029336655.2 7865 8598 5311 6174 4694 Q53HC0 3.72e-23 Coiled-coil domain-containing protein 92 (Limkain beta-2) Homo sapiens (Human) innate immune response [GO:0045087]; regulation of defense response to virus [GO:0050688] GO:0005654; GO:0005737; GO:0005813; GO:0005814; GO:0042802; GO:0043231; GO:0045087; GO:0050688 49592 XM_044317854.1 2984 1574 894 2295 1304 NA NA NA NA NA NA 49593 XR_006397666.1 938 654 544 869 1142 Q497V6 1.26e-46 Bromo adjacent homology domain-containing 1 protein (BAH domain-containing protein 1) Mus musculus (Mouse) heterochromatin formation [GO:0031507]; negative regulation of DNA-templated transcription [GO:0045892] GO:0000976; GO:0003682; GO:0005654; GO:0005677; GO:0005694; GO:0031507; GO:0045892 49594 XR_006396287.1 220 173 101 288 106 Q00808 1.33e-47 Vegetative incompatibility protein HET-E-1 Podospora anserina (Pleurage anserina) NA GO:0005525 49595 XR_006396287.1 220 173 101 288 106 Q00808 1.33e-47 Vegetative incompatibility protein HET-E-1 Podospora anserina (Pleurage anserina) NA GO:0005525 49596 XR_006396287.1 220 173 101 288 106 Q00808 4.17e-39 Vegetative incompatibility protein HET-E-1 Podospora anserina (Pleurage anserina) NA GO:0005525 49597 XR_006396287.1 220 173 101 288 106 Q00808 1.71e-35 Vegetative incompatibility protein HET-E-1 Podospora anserina (Pleurage anserina) NA GO:0005525 49598 XR_006396287.1 220 173 101 288 106 Q00808 2.86e-25 Vegetative incompatibility protein HET-E-1 Podospora anserina (Pleurage anserina) NA GO:0005525 49599 XM_029339948.2 0 58 0 132 368 NA NA NA NA NA NA 49600 XR_006392139.1 80 79 13 97 54 NA NA NA NA NA NA 49601 XM_029335380.2 91 64 52 104 148 Q13112 6.84e-150 Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-I p60) (M-phase phosphoprotein 7) Homo sapiens (Human) cell cycle [GO:0007049]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication-dependent chromatin assembly [GO:0006335]; nucleosome assembly [GO:0006334] GO:0000785; GO:0003682; GO:0005634; GO:0005654; GO:0005737; GO:0006260; GO:0006281; GO:0006334; GO:0006335; GO:0007049; GO:0032991; GO:0033186; GO:0042393; GO:0051082 49602 XM_029356060.2 311 230 292 237 358 Q8MIZ3 3.77e-105 m7GpppX diphosphatase (EC 3.6.1.59) (DCS-1) (Decapping scavenger enzyme) (Hint-related 7meGMP-directed hydrolase) (Histidine triad nucleotide-binding protein 5) (Histidine triad protein member 5) (HINT-5) (Scavenger mRNA-decapping enzyme DcpS) Sus scrofa (Pig) cellular response to menadione [GO:0036245]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; mRNA cis splicing, via spliceosome [GO:0045292]; negative regulation of programmed cell death [GO:0043069] GO:0000290; GO:0000340; GO:0000932; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005829; GO:0036245; GO:0042802; GO:0043069; GO:0045292; GO:0050072; GO:0140932 49603 XM_029335455.2 580 115 213 355 623 NA NA NA NA NA NA 49604 XM_029333370.1 1 102 99 168 86 B0BN49 2.56e-47 RNA-binding motif protein, X-linked 2 Rattus norvegicus (Rat) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0003723; GO:0005634; GO:0005686; GO:0071005; GO:0071011 49605 XR_006398048.1 8 15 2 10 85 NA NA NA NA NA NA 49606 XR_003827966.2 11 8 4 0 0 NA NA NA NA NA NA 49607 XM_029338848.2 238 136 95 123 121 A4IGP0 6.46e-84 Protein Hikeshi Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cellular response to heat [GO:0034605]; protein import into nucleus [GO:0006606]; protein transport [GO:0015031] GO:0005634; GO:0005829; GO:0006606; GO:0015031; GO:0030544; GO:0034605 49608 XM_029352660.2 550 302 274 483 481 Q0IJ05 0 Oxysterol-binding protein-related protein 9 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) lipid transport [GO:0006869] GO:0006869; GO:0008289 49609 XM_029352660.2 550 302 274 483 481 Q0IJ05 1.23e-59 Oxysterol-binding protein-related protein 9 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) lipid transport [GO:0006869] GO:0006869; GO:0008289 49610 XM_029358536.2 34 1 1 20 2 B8VIU6 2.1e-54 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 49611 XM_029328771.2 110 145 141 238 315 NA NA NA NA NA NA 49612 XM_044316429.1 0 0 0 0 7 NA NA NA NA NA NA 49613 XM_029348387.2 6 0 2 0 5 NA NA NA NA NA NA 49614 XM_044322949.1 746 231 275 560 679 Q9NZJ4 0 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 49615 XM_044322949.1 746 231 275 560 679 Q9NZJ4 2.86e-50 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 49616 XM_029331716.2 0 4 0 271 145 Q5T1B0 2.96e-143 Axonemal dynein light chain domain-containing protein 1 Homo sapiens (Human) NA NA 49617 XM_029334157.2 1084 1216 1281 1401 957 A7SK27 3e-130 Probable ethanolamine kinase (EC 2.7.1.82) Nematostella vectensis (Starlet sea anemone) phosphatidylethanolamine biosynthetic process [GO:0006646]; phosphorylation [GO:0016310] GO:0004305; GO:0005524; GO:0005737; GO:0006646; GO:0016310 49618 XM_044308993.1 96 84 120 247 138 NA NA NA NA NA NA 49619 XR_006398199.1 0 0 0 118 0 NA NA NA NA NA NA 49620 XM_029348365.2 0 369 38 115 312 Q9V3D5 6.29e-38 Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1) (Protein smell impaired at 35A) (dDyrk2) Drosophila melanogaster (Fruit fly) olfactory behavior [GO:0042048]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of Wnt signaling pathway [GO:0030177]; protein phosphorylation [GO:0006468]; response to light stimulus [GO:0009416]; sensory perception of smell [GO:0007608] GO:0004674; GO:0004712; GO:0004713; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0005856; GO:0006468; GO:0007608; GO:0009416; GO:0018105; GO:0018107; GO:0030177; GO:0042048; GO:0106310 49621 XM_044319961.1 58 4 0 87 178 Q8MIQ9 3.35e-126 P protein (Melanocyte-specific transporter protein) (Pink-eyed dilution protein homolog) Sus scrofa (Pig) lysosomal lumen pH elevation [GO:0035752]; melanin biosynthetic process [GO:0042438]; melanin biosynthetic process from tyrosine [GO:0006583]; melanocyte differentiation [GO:0030318] GO:0006583; GO:0030318; GO:0033162; GO:0035752; GO:0042438; GO:0061778 49622 XM_029351069.2 61 6 40 91 50 Q9N126 1.76e-63 Retinol dehydrogenase 8 (EC 1.1.1.300) (Photoreceptor outer segment all-trans retinol dehydrogenase) Bos taurus (Bovine) estrogen biosynthetic process [GO:0006703]; response to stimulus [GO:0050896]; retinol metabolic process [GO:0042572]; visual perception [GO:0007601] GO:0004303; GO:0004745; GO:0005829; GO:0006703; GO:0007601; GO:0016491; GO:0042572; GO:0042622; GO:0050896; GO:0052650 49623 XM_029345593.2 15033 15244 9481 15232 11349 Q9N1R6 1.25e-116 b(0,+)-type amino acid transporter 1 (b(0,+)AT) (4F2-LC6) (Glycoprotein-associated amino acid transporter b0,+AT1) (Solute carrier family 7 member 9) Oryctolagus cuniculus (Rabbit) L-cystine transport [GO:0015811]; neutral amino acid transport [GO:0015804] GO:0005886; GO:0015175; GO:0015184; GO:0015804; GO:0015811; GO:0016020; GO:0016324; GO:0031526; GO:0042605 49624 XR_006393528.1 0 14 0 33 22 NA NA NA NA NA NA 49625 XM_029333802.2 15 6 11 28 6 NA NA NA NA NA NA 49626 XM_029328755.2 191 148 163 95 210 Q6PCX9 0 E3 ubiquitin-protein ligase TRIM37 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TRIM37) (Tripartite motif-containing protein 37) Mus musculus (Mouse) aggresome assembly [GO:0070842]; histone H2A monoubiquitination [GO:0035518]; histone H2A-K119 monoubiquitination [GO:0036353]; negative regulation of centriole replication [GO:0046600]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein autoubiquitination [GO:0051865]; protein import into peroxisome matrix [GO:0016558] GO:0000122; GO:0003682; GO:0003713; GO:0004842; GO:0005164; GO:0005694; GO:0005737; GO:0005777; GO:0005778; GO:0005829; GO:0008270; GO:0016235; GO:0016558; GO:0031625; GO:0032088; GO:0035098; GO:0035518; GO:0036353; GO:0042803; GO:0046600; GO:0048471; GO:0051091; GO:0051092; GO:0051865; GO:0061630; GO:0070842 49627 XM_029351709.2 593 714 347 870 386 Q8WXG1 4.59e-162 S-adenosylmethionine-dependent nucleotide dehydratase RSAD2 (SAND) (EC 4.2.-.-) (Cytomegalovirus-induced gene 5 protein) (Radical S-adenosyl methionine domain-containing protein 2) (Virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible) (Viperin) Homo sapiens (Human) CD4-positive, alpha-beta T cell activation [GO:0035710]; CD4-positive, alpha-beta T cell differentiation [GO:0043367]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of protein secretion [GO:0050709]; negative regulation of viral genome replication [GO:0045071]; positive regulation of immune response [GO:0050778]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of toll-like receptor 7 signaling pathway [GO:0034157]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; response to virus [GO:0009615] GO:0001650; GO:0005739; GO:0005741; GO:0005743; GO:0005783; GO:0005789; GO:0005794; GO:0005811; GO:0009615; GO:0016829; GO:0034157; GO:0034165; GO:0035710; GO:0043367; GO:0043621; GO:0045071; GO:0045087; GO:0046872; GO:0050709; GO:0050778; GO:0051539; GO:0051607; GO:2000553 49628 XM_029343499.2 112 50 27 73 73 NA NA NA NA NA NA 49629 XR_006396159.1 221 244 112 296 58 NA NA NA NA NA NA 49630 XM_029351711.2 170 378 96 321 279 Q5U249 5.62e-160 Protein ELYS (Protein MEL-28) (xELYS) Xenopus laevis (African clawed frog) mRNA transport [GO:0051028]; protein transport [GO:0015031] GO:0003677; GO:0005643; GO:0005654; GO:0005737; GO:0015031; GO:0051028 49631 XM_029348063.2 0 151 359 66 455 NA NA NA NA NA NA 49632 XM_029328451.2 376 347 0 0 572 Q63665 3.03e-60 Upstream stimulatory factor 2 (Major late transcription factor 2) (Upstream transcription factor 2) Rattus norvegicus (Rat) lactation [GO:0007595]; lipid homeostasis [GO:0055088]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter by glucose [GO:0000432]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000432; GO:0000978; GO:0000981; GO:0003677; GO:0003690; GO:0003700; GO:0005634; GO:0006357; GO:0007595; GO:0042802; GO:0042803; GO:0043425; GO:0043565; GO:0044877; GO:0045893; GO:0045944; GO:0046982; GO:0055088; GO:1990837 49633 XM_044307884.1 67 276 87 170 176 E7FAM5 1.91e-55 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 49634 XM_044307884.1 67 276 87 170 176 E7FAM5 1.29e-54 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 49635 XM_044314522.1 711 908 657 922 917 Q9TRY0 8.21e-115 Peptidyl-prolyl cis-trans isomerase FKBP4 (PPIase FKBP4) (EC 5.2.1.8) (52 kDa FK506-binding protein) (52 kDa FKBP) (FKBP-52) (FK506-binding protein 4) (FKBP-4) (HSP-binding immunophilin) (HBI) (Immunophilin FKBP52) (Rotamase) [Cleaved into: Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed] Bos taurus (Bovine) chaperone-mediated protein folding [GO:0061077]; negative regulation of microtubule polymerization or depolymerization [GO:0031111]; negative regulation of neuron projection development [GO:0010977] GO:0003755; GO:0005634; GO:0005739; GO:0005829; GO:0005874; GO:0010977; GO:0031111; GO:0044295; GO:0061077 49636 XM_044307448.1 129 130 59 0 27 Q8BZM0 1.86e-40 Kelch-like protein 12 (CUL3-interacting protein 1) Mus musculus (Mouse) COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; protein monoubiquitination [GO:0006513]; Wnt signaling pathway [GO:0016055] GO:0006513; GO:0006888; GO:0014029; GO:0014032; GO:0016055; GO:0030127; GO:0030134; GO:0031463; GO:0034451; GO:0042802; GO:0043231; GO:0048208 49637 XM_044317656.1 25 25 22 46 77 P15989 3.34e-25 Collagen alpha-3(VI) chain Gallus gallus (Chicken) cell adhesion [GO:0007155]; negative regulation of peptidase activity [GO:0010466] GO:0004867; GO:0005581; GO:0005615; GO:0007155; GO:0010466; GO:0062023 49638 XM_044313470.1 1 2 15 0 49 NA NA NA NA NA NA 49639 XM_044316601.1 11 38 20 28 3 NA NA NA NA NA NA 49640 XR_006395678.1 24 15 11 27 8 NA NA NA NA NA NA 49641 XM_029349340.2 886 979 739 974 955 Q6GMH0 3.79e-113 Pre-mRNA-splicing factor 18 (PRP18 homolog) Danio rerio (Zebrafish) (Brachydanio rerio) generation of catalytic spliceosome for second transesterification step [GO:0000350] GO:0000350; GO:0005682; GO:0016607; GO:0046540; GO:0071021 49642 XM_029329654.2 308 446 118 367 503 B2RRD7 2.52e-156 Peregrin (Bromodomain and PHD finger-containing protein 1) Mus musculus (Mouse) chromatin organization [GO:0006325]; common myeloid progenitor cell proliferation [GO:0035726]; histone H3-K23 acetylation [GO:0043972]; neural tube formation [GO:0001841]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA-templated transcription [GO:0006355]; regulation of fibroblast proliferation [GO:0048145]; regulation of transcription by RNA polymerase II [GO:0006357]; vasculogenesis [GO:0001570] GO:0000123; GO:0001570; GO:0001841; GO:0003677; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0006325; GO:0006355; GO:0006357; GO:0010698; GO:0035726; GO:0043972; GO:0043995; GO:0043996; GO:0043997; GO:0045893; GO:0046872; GO:0048145; GO:0070776 49643 XM_029329654.2 308 446 118 367 503 B2RRD7 1.7e-85 Peregrin (Bromodomain and PHD finger-containing protein 1) Mus musculus (Mouse) chromatin organization [GO:0006325]; common myeloid progenitor cell proliferation [GO:0035726]; histone H3-K23 acetylation [GO:0043972]; neural tube formation [GO:0001841]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA-templated transcription [GO:0006355]; regulation of fibroblast proliferation [GO:0048145]; regulation of transcription by RNA polymerase II [GO:0006357]; vasculogenesis [GO:0001570] GO:0000123; GO:0001570; GO:0001841; GO:0003677; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0006325; GO:0006355; GO:0006357; GO:0010698; GO:0035726; GO:0043972; GO:0043995; GO:0043996; GO:0043997; GO:0045893; GO:0046872; GO:0048145; GO:0070776 49644 XM_029329654.2 308 446 118 367 503 B2RRD7 1.88e-38 Peregrin (Bromodomain and PHD finger-containing protein 1) Mus musculus (Mouse) chromatin organization [GO:0006325]; common myeloid progenitor cell proliferation [GO:0035726]; histone H3-K23 acetylation [GO:0043972]; neural tube formation [GO:0001841]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA-templated transcription [GO:0006355]; regulation of fibroblast proliferation [GO:0048145]; regulation of transcription by RNA polymerase II [GO:0006357]; vasculogenesis [GO:0001570] GO:0000123; GO:0001570; GO:0001841; GO:0003677; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0006325; GO:0006355; GO:0006357; GO:0010698; GO:0035726; GO:0043972; GO:0043995; GO:0043996; GO:0043997; GO:0045893; GO:0046872; GO:0048145; GO:0070776 49645 XR_003824736.2 3 0 26 0 81 NA NA NA NA NA NA 49646 XM_029347337.2 2409 2002 1805 2250 2275 Q8N159 1.33e-92 N-acetylglutamate synthase, mitochondrial (EC 2.3.1.1) (Amino-acid acetyltransferase) [Cleaved into: N-acetylglutamate synthase long form; N-acetylglutamate synthase short form; N-acetylglutamate synthase conserved domain form] Homo sapiens (Human) arginine biosynthetic process [GO:0006526]; glutamate metabolic process [GO:0006536]; urea cycle [GO:0000050] GO:0000050; GO:0004042; GO:0005739; GO:0005759; GO:0006526; GO:0006536; GO:0103045 49647 XM_044327451.1 18 2 38 3 24 Q91ZV2 4.05e-29 Discoidin, CUB and LCCL domain-containing protein 2 (Endothelial and smooth muscle cell-derived neuropilin-like protein) Rattus norvegicus (Rat) negative regulation of cell growth [GO:0030308]; wound healing [GO:0042060] GO:0005886; GO:0009986; GO:0030308; GO:0038023; GO:0042060 49648 XM_029329732.2 167 19 163 360 99 Q8K0U4 2.34e-133 Heat shock 70 kDa protein 12A Mus musculus (Mouse) NA GO:0005524; GO:0005634; GO:0005737 49649 XM_029341749.2 405 314 157 453 269 NA NA NA NA NA NA 49650 XM_029338235.2 1849 1181 1941 2295 1856 NA NA NA NA NA NA 49651 XM_044308558.1 4052 1854 2133 1834 2378 Q28104 1.24e-107 Coatomer subunit epsilon (Epsilon-coat protein) (Epsilon-COP) Bos taurus (Bovine) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein localization to axon [GO:0099612]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] GO:0000139; GO:0005198; GO:0005654; GO:0006888; GO:0006890; GO:0006891; GO:0015031; GO:0030126; GO:0099612 49652 XM_044319365.1 10 30 0 16 9 P0CI65 4.54e-58 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 49653 XM_044319365.1 10 30 0 16 9 P0CI65 1.14e-42 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 49654 XM_044319365.1 10 30 0 16 9 P0CI65 4.95e-38 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 49655 XM_044319365.1 10 30 0 16 9 P0CI65 5.07e-31 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 49656 XM_029343860.2 5048 5232 3215 4732 3261 E9PV86 0 Multiple C2 and transmembrane domain-containing protein 1 Mus musculus (Mouse) negative regulation of cell migration [GO:0030336]; negative regulation of endocytosis [GO:0045806]; negative regulation of response to oxidative stress [GO:1902883]; regulation of neurotransmitter secretion [GO:0046928] GO:0005509; GO:0005789; GO:0016020; GO:0030336; GO:0030672; GO:0045806; GO:0046928; GO:0055037; GO:1902883 49657 XM_044307624.1 284 994 71 575 573 NA NA NA NA NA NA 49658 XR_006397654.1 8 0 0 0 0 NA NA NA NA NA NA 49659 XM_044321712.1 0 416 2 0 0 A4D0V7 9.1e-109 Cadherin-like and PC-esterase domain-containing protein 1 Homo sapiens (Human) NA GO:0005783 49660 XM_029350152.2 158 72 147 519 179 NA NA NA NA NA NA 49661 XR_006397250.1 169 35 0 6 6 NA NA NA NA NA NA 49662 XR_006395522.1 150 102 192 52 37 NA NA NA NA NA NA 49663 XM_044310689.1 191 223 241 260 364 NA NA NA NA NA NA 49664 XM_029336899.2 1880 2294 1892 2713 1717 NA NA NA NA NA NA 49665 XM_044316284.1 2 5 12 6 10 Q80XJ3 4.2e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 49666 XR_006393844.1 43 3 19 1 52 NA NA NA NA NA NA 49667 XR_003826123.2 28 34 23 68 34 NA NA NA NA NA NA 49668 XM_044314068.1 63 30 48 47 128 NA NA NA NA NA NA 49669 XR_006396123.1 1114 713 593 1337 992 Q18297 3.42e-124 Transient receptor potential cation channel subfamily A member 1 homolog Caenorhabditis elegans response to stimulus [GO:0050896] GO:0005216; GO:0005886; GO:0043025; GO:0050896; GO:0097730 49670 XR_006396123.1 1114 713 593 1337 992 Q18297 3.42e-124 Transient receptor potential cation channel subfamily A member 1 homolog Caenorhabditis elegans response to stimulus [GO:0050896] GO:0005216; GO:0005886; GO:0043025; GO:0050896; GO:0097730 49671 XR_006396123.1 1114 713 593 1337 992 Q18297 2.44e-25 Transient receptor potential cation channel subfamily A member 1 homolog Caenorhabditis elegans response to stimulus [GO:0050896] GO:0005216; GO:0005886; GO:0043025; GO:0050896; GO:0097730 49672 XM_044323072.1 0 6 34 9 0 NA NA NA NA NA NA 49673 XR_006391945.1 52 10 155 56 137 NA NA NA NA NA NA 49674 XM_044318243.1 419 237 212 280 512 Q9HAR2 9.93e-67 Adhesion G protein-coupled receptor L3 (Calcium-independent alpha-latrotoxin receptor 3) (CIRL-3) (Latrophilin-3) (Lectomedin-3) Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; brain development [GO:0007420]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; G protein-coupled receptor signaling pathway [GO:0007186]; neuron migration [GO:0001764]; synapse assembly [GO:0007416] GO:0001764; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007166; GO:0007186; GO:0007189; GO:0007416; GO:0007420; GO:0016020; GO:0030246; GO:0030424; GO:0098742; GO:0098978 49675 XR_006392977.1 41 2 25 5 151 NA NA NA NA NA NA 49676 XM_029345696.2 51 53 49 75 99 Q9Y4W2 3.31e-21 Ribosomal biogenesis protein LAS1L (Protein LAS1 homolog) Homo sapiens (Human) maturation of 5.8S rRNA [GO:0000460]; maturation of LSU-rRNA [GO:0000470] GO:0000460; GO:0000470; GO:0003723; GO:0004519; GO:0005654; GO:0005730; GO:0016020; GO:0030687; GO:0071339; GO:0090730 49677 XM_029333397.2 228 212 143 251 211 H3BCW1 5.71e-74 ADP-ribosylhydrolase ARH3 (ADP-ribose glycohydrolase ARH3) (LchARH3) (ADP-ribosylhydrolase 3) (O-acetyl-ADP-ribose deacetylase ARH3) (EC 3.5.1.-) (Poly(ADP-ribose) glycohydrolase ARH3) (EC 3.2.1.143) ([Protein ADP-ribosylarginine] hydrolase-like protein 2) ([Protein ADP-ribosylserine] hydrolase) (EC 3.2.2.-) Latimeria chalumnae (Coelacanth) DNA repair [GO:0006281]; negative regulation of necroptotic process [GO:0060546]; peptidyl-serine ADP-deribosylation [GO:0140290] GO:0000287; GO:0004649; GO:0005634; GO:0005694; GO:0005759; GO:0006281; GO:0060546; GO:0140290 49678 XR_006395717.1 0 37 0 139 69 NA NA NA NA NA NA 49679 XM_044322807.1 61 0 10 145 11 Q13591 1.22e-71 Semaphorin-5A (Semaphorin-F) (Sema F) Homo sapiens (Human) axon extension [GO:0048675]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell-cell signaling [GO:0007267]; diencephalon development [GO:0021536]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of cell adhesion [GO:0007162]; negative regulation of endothelial cell apoptotic process [GO:2000352]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; positive chemotaxis [GO:0050918]; positive regulation of actin filament depolymerization [GO:0030836]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein kinase B signaling [GO:0051897]; semaphorin-plexin signaling pathway [GO:0071526]; signal clustering [GO:1990256] GO:0001755; GO:0001938; GO:0002043; GO:0005886; GO:0007155; GO:0007162; GO:0007267; GO:0007399; GO:0007411; GO:0007413; GO:0016020; GO:0021536; GO:0030215; GO:0030335; GO:0030836; GO:0035373; GO:0043395; GO:0045499; GO:0045545; GO:0045766; GO:0048675; GO:0048842; GO:0048843; GO:0050918; GO:0051897; GO:0060326; GO:0070062; GO:0071526; GO:0090263; GO:1990256; GO:2000352; GO:2001028 49680 XM_029332533.2 4004 3404 2013 3095 2398 Q9VJ79 0 Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11 (EC 3.1.4.35) (EC 3.1.4.53) (cAMP and cGMP phosphodiesterase 11) (PDE11) Drosophila melanogaster (Fruit fly) cAMP metabolic process [GO:0046058]; cGMP metabolic process [GO:0046068]; signal transduction [GO:0007165] GO:0004114; GO:0004115; GO:0005829; GO:0007165; GO:0046058; GO:0046068; GO:0046872; GO:0047555 49681 XM_044314479.1 73 570 888 836 1094 Q9JLC8 0 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Mus musculus (Mouse) negative regulation of inclusion body assembly [GO:0090084] GO:0005634; GO:0005737; GO:0005739; GO:0030544; GO:0042802; GO:0050750; GO:0051087; GO:0070628; GO:0090084 49682 XM_044314479.1 73 570 888 836 1094 Q9JLC8 6.65e-40 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Mus musculus (Mouse) negative regulation of inclusion body assembly [GO:0090084] GO:0005634; GO:0005737; GO:0005739; GO:0030544; GO:0042802; GO:0050750; GO:0051087; GO:0070628; GO:0090084 49683 XM_029328949.2 83 27 423 0 1 P43404 5.51e-83 Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-chain associated protein) (Syk-related tyrosine kinase) Mus musculus (Mouse) adaptive immune response [GO:0002250]; alpha-beta T cell differentiation [GO:0046632]; beta selection [GO:0043366]; calcium-mediated signaling [GO:0019722]; cell differentiation [GO:0030154]; immune response [GO:0006955]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; negative thymic T cell selection [GO:0045060]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of T cell differentiation [GO:0045582]; positive thymic T cell selection [GO:0045059]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; thymic T cell selection [GO:0045061]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0001772; GO:0001784; GO:0002250; GO:0004672; GO:0004713; GO:0004715; GO:0005102; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0005911; GO:0006468; GO:0006955; GO:0007169; GO:0016020; GO:0018108; GO:0019722; GO:0030154; GO:0030217; GO:0031234; GO:0035556; GO:0042101; GO:0043366; GO:0045059; GO:0045060; GO:0045061; GO:0045087; GO:0045121; GO:0045582; GO:0046632; GO:0046638; GO:0046641; GO:0046777; GO:0050850; GO:0050852 49684 XM_029328949.2 83 27 423 0 1 P43404 3.65e-39 Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-chain associated protein) (Syk-related tyrosine kinase) Mus musculus (Mouse) adaptive immune response [GO:0002250]; alpha-beta T cell differentiation [GO:0046632]; beta selection [GO:0043366]; calcium-mediated signaling [GO:0019722]; cell differentiation [GO:0030154]; immune response [GO:0006955]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; negative thymic T cell selection [GO:0045060]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of T cell differentiation [GO:0045582]; positive thymic T cell selection [GO:0045059]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; thymic T cell selection [GO:0045061]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0001772; GO:0001784; GO:0002250; GO:0004672; GO:0004713; GO:0004715; GO:0005102; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0005911; GO:0006468; GO:0006955; GO:0007169; GO:0016020; GO:0018108; GO:0019722; GO:0030154; GO:0030217; GO:0031234; GO:0035556; GO:0042101; GO:0043366; GO:0045059; GO:0045060; GO:0045061; GO:0045087; GO:0045121; GO:0045582; GO:0046632; GO:0046638; GO:0046641; GO:0046777; GO:0050850; GO:0050852 49685 XM_029336019.2 166 89 84 52 60 NA NA NA NA NA NA 49686 XM_044328181.1 10 0 0 0 0 NA NA NA NA NA NA 49687 XM_029350669.2 333 108 59 1074 406 P54288 2.46e-125 Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2) Oryctolagus cuniculus (Rabbit) calcium ion import [GO:0070509]; chemical synaptic transmission [GO:0007268]; membrane depolarization during atrial cardiac muscle cell action potential [GO:0098912]; positive regulation of calcium ion transport [GO:0051928]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ion transmembrane transport [GO:0034765]; visual perception [GO:0007601] GO:0007268; GO:0007601; GO:0008331; GO:0034765; GO:0051015; GO:0051928; GO:0070509; GO:0086056; GO:0086091; GO:0098684; GO:0098793; GO:0098912; GO:0099626; GO:1990454 49688 XM_044327605.1 395 241 230 550 442 C0HL12 6.1e-31 Adhesion G protein-coupled receptor B1 (Brain-specific angiogenesis inhibitor 1) [Cleaved into: Vasculostatin-120 (Vstat120); Vasculostatin-40 (Vstat-40)] Rattus norvegicus (Rat) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; apoptotic cell clearance [GO:0043277]; cell surface receptor signaling pathway [GO:0007166]; defense response to Gram-negative bacterium [GO:0050829]; engulfment of apoptotic cell [GO:0043652]; innate immune response [GO:0045087]; muscle organ development [GO:0007517]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein ubiquitination [GO:0031397]; nervous system development [GO:0007399]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of synapse assembly [GO:0051965]; postsynaptic actin cytoskeleton organization [GO:0098974]; regulation of synaptic plasticity [GO:0048167] GO:0001530; GO:0001786; GO:0001891; GO:0004888; GO:0004930; GO:0005615; GO:0005886; GO:0005925; GO:0006910; GO:0006911; GO:0007166; GO:0007189; GO:0007399; GO:0007517; GO:0010596; GO:0014069; GO:0016525; GO:0030165; GO:0030425; GO:0031397; GO:0042177; GO:0043197; GO:0043277; GO:0043652; GO:0045087; GO:0045211; GO:0048167; GO:0048471; GO:0050829; GO:0051965; GO:0098974; GO:0098978; GO:1901741; GO:1903428 49689 XM_029332544.2 10 6 16 4 18 NA NA NA NA NA NA 49690 XM_044321735.1 112 0 83 70 0 A7SBN6 1.74e-129 Zinc finger CCCH-type with G patch domain-containing protein Nematostella vectensis (Starlet sea anemone) negative regulation of DNA-templated transcription [GO:0045892]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0045892; GO:0046872 49691 XM_044320538.1 1743 1443 905 2295 1847 B2KI97 0 THO complex subunit 2 (Tho2) Rhinolophus ferrumequinum (Greater horseshoe bat) generation of neurons [GO:0048699]; mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; neuron development [GO:0048666]; RNA splicing [GO:0008380] GO:0000347; GO:0003723; GO:0006397; GO:0006406; GO:0008380; GO:0016607; GO:0048666; GO:0048699 49692 XM_044309372.1 219 42 245 128 247 NA NA NA NA NA NA 49693 XM_029329662.2 2029 1526 816 1502 1476 P16912 6.39e-147 cAMP-dependent protein kinase catalytic subunit 3 (EC 2.7.11.1) (Protein kinase DC2) Drosophila melanogaster (Fruit fly) imaginal disc-derived wing morphogenesis [GO:0007476]; peptidyl-serine phosphorylation [GO:0018105]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165] GO:0004691; GO:0005524; GO:0005952; GO:0006468; GO:0007165; GO:0007476; GO:0018105; GO:0106310 49694 XM_029331851.2 825 1090 604 1221 1029 Q9CWM4 6.96e-31 Prefoldin subunit 1 Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; B cell activation [GO:0042113]; cerebellum development [GO:0021549]; negative regulation of amyloid fibril formation [GO:1905907]; protein folding [GO:0006457]; telencephalon development [GO:0021537] GO:0001540; GO:0005737; GO:0006457; GO:0016272; GO:0021537; GO:0021549; GO:0030036; GO:0042113; GO:0044183; GO:0051082; GO:1905907 49695 XM_044322254.1 308 274 486 659 612 Q5ZK62 0 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 (Centaurin-beta-2) (Cnt-b2) Gallus gallus (Chicken) cellular response to nerve growth factor stimulus [GO:1990090]; endocytic recycling [GO:0032456] GO:0005096; GO:0010008; GO:0032456; GO:0046872; GO:1990090 49696 XM_029344528.2 2488 1860 1608 2851 2207 Q09JY9 2.25e-23 Protein Shroom2 (Protein Apxl) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) apical protein localization [GO:0045176]; brain development [GO:0007420]; camera-type eye development [GO:0043010]; camera-type eye morphogenesis [GO:0048593]; cell migration [GO:0016477]; cellular pigment accumulation [GO:0043482]; ear development [GO:0043583]; establishment of melanosome localization [GO:0032401]; eye pigment granule organization [GO:0008057]; lens morphogenesis in camera-type eye [GO:0002089]; melanosome organization [GO:0032438] GO:0002089; GO:0003779; GO:0005737; GO:0005856; GO:0005874; GO:0005886; GO:0005923; GO:0007420; GO:0008057; GO:0016324; GO:0016477; GO:0032401; GO:0032438; GO:0043010; GO:0043482; GO:0043583; GO:0045176; GO:0048593; GO:0051015 49697 XR_006397833.1 448 218 270 208 251 NA NA NA NA NA NA 49698 XR_006393754.1 22 5 5 169 18 NA NA NA NA NA NA 49699 XR_006391663.1 0 2 7 8 46 NA NA NA NA NA NA 49700 XM_044325980.1 195 123 81 68 198 NA NA NA NA NA NA 49701 XM_044321434.1 134 195 52 101 106 W7LUF3 1.63e-41 Dehydrogenase FUM7 (EC 1.14.11.-) (Fumonisin biosynthesis cluster protein 7) Gibberella moniliformis (strain M3125 / FGSC 7600) (Maize ear and stalk rot fungus) (Fusarium verticillioides) fumonisin biosynthetic process [GO:1900541] GO:0016491; GO:0046872; GO:1900541 49702 XM_029335232.2 1120 643 427 757 749 Q6NYL5 1.37e-154 Alanine aminotransferase 2-like (ALT2) (EC 2.6.1.2) (Glutamate pyruvate transaminase 2) (GPT 2) (Glutamic--alanine transaminase 2) (Glutamic--pyruvic transaminase 2) Danio rerio (Zebrafish) (Brachydanio rerio) 2-oxoglutarate metabolic process [GO:0006103]; biosynthetic process [GO:0009058]; L-alanine catabolic process [GO:0042853]; L-alanine metabolic process [GO:0042851] GO:0004021; GO:0006103; GO:0009058; GO:0030170; GO:0042851; GO:0042853 49703 XR_003828560.2 2 13 5 9 31 NA NA NA NA NA NA 49704 XR_006398010.1 117 36 31 69 65 NA NA NA NA NA NA 49705 XM_044316518.1 15 1 9 44 20 NA NA NA NA NA NA 49706 XM_044323494.1 39 3 8 103 43 NA NA NA NA NA NA 49707 XM_029357265.2 238 171 147 245 353 Q9UIK4 1.92e-42 Death-associated protein kinase 2 (DAP kinase 2) (EC 2.7.11.1) (DAP-kinase-related protein 1) (DRP-1) Homo sapiens (Human) anoikis [GO:0043276]; apoptotic process [GO:0006915]; intracellular signal transduction [GO:0035556]; positive regulation of apoptotic process [GO:0043065]; positive regulation of eosinophil chemotaxis [GO:2000424]; positive regulation of neutrophil chemotaxis [GO:0090023]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of autophagy [GO:0010506]; regulation of intrinsic apoptotic signaling pathway [GO:2001242] GO:0004674; GO:0005516; GO:0005524; GO:0005634; GO:0005737; GO:0005794; GO:0006468; GO:0006915; GO:0010506; GO:0031410; GO:0034423; GO:0035556; GO:0042802; GO:0042981; GO:0043065; GO:0043231; GO:0043276; GO:0046777; GO:0090023; GO:0106310; GO:2000424; GO:2001242 49708 XR_006392366.1 0 8 3 0 0 NA NA NA NA NA NA 49709 XM_044313525.1 149 69 87 153 157 NA NA NA NA NA NA 49710 XM_044319721.1 364 129 96 254 261 A7MBL8 0 Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like 2) (Protein-kinase C-related kinase 2) Danio rerio (Zebrafish) (Brachydanio rerio) cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell division [GO:0051301]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105] GO:0004674; GO:0004698; GO:0005524; GO:0005634; GO:0005737; GO:0005856; GO:0007049; GO:0007155; GO:0018105; GO:0030027; GO:0030496; GO:0031267; GO:0032154; GO:0035556; GO:0051301; GO:0070161; GO:0106310 49711 XM_044310613.1 53 46 7 31 22 P13595 6.17e-40 Neural cell adhesion molecule 1 (N-CAM-1) (NCAM-1) (CD antigen CD56) Mus musculus (Mouse) aging [GO:0007568]; axonal fasciculation [GO:0007413]; calcium-mediated signaling [GO:0019722]; cell surface receptor signaling pathway [GO:0007166]; commissural neuron axon guidance [GO:0071679]; homotypic cell-cell adhesion [GO:0034109]; learning or memory [GO:0007611]; modulation of chemical synaptic transmission [GO:0050804]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell death [GO:0060548]; neuron development [GO:0048666]; neuron projection development [GO:0031175]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; regulation of exocyst assembly [GO:0001928]; regulation of semaphorin-plexin signaling pathway [GO:2001260]; regulation of sensory perception of pain [GO:0051930]; response to cocaine [GO:0042220]; response to lead ion [GO:0010288]; response to xenobiotic stimulus [GO:0009410]; thalamus development [GO:0021794] GO:0001928; GO:0005829; GO:0005886; GO:0005911; GO:0007166; GO:0007413; GO:0007568; GO:0007611; GO:0008201; GO:0009410; GO:0009897; GO:0009986; GO:0010288; GO:0019722; GO:0019902; GO:0021794; GO:0030275; GO:0030424; GO:0030426; GO:0031175; GO:0033555; GO:0034109; GO:0042220; GO:0042734; GO:0043005; GO:0043025; GO:0043209; GO:0045211; GO:0048666; GO:0050804; GO:0050850; GO:0051930; GO:0060045; GO:0060548; GO:0071679; GO:0098685; GO:0098978; GO:2001260 49712 XM_044310613.1 53 46 7 31 22 P13595 6.17e-40 Neural cell adhesion molecule 1 (N-CAM-1) (NCAM-1) (CD antigen CD56) Mus musculus (Mouse) aging [GO:0007568]; axonal fasciculation [GO:0007413]; calcium-mediated signaling [GO:0019722]; cell surface receptor signaling pathway [GO:0007166]; commissural neuron axon guidance [GO:0071679]; homotypic cell-cell adhesion [GO:0034109]; learning or memory [GO:0007611]; modulation of chemical synaptic transmission [GO:0050804]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell death [GO:0060548]; neuron development [GO:0048666]; neuron projection development [GO:0031175]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; regulation of exocyst assembly [GO:0001928]; regulation of semaphorin-plexin signaling pathway [GO:2001260]; regulation of sensory perception of pain [GO:0051930]; response to cocaine [GO:0042220]; response to lead ion [GO:0010288]; response to xenobiotic stimulus [GO:0009410]; thalamus development [GO:0021794] GO:0001928; GO:0005829; GO:0005886; GO:0005911; GO:0007166; GO:0007413; GO:0007568; GO:0007611; GO:0008201; GO:0009410; GO:0009897; GO:0009986; GO:0010288; GO:0019722; GO:0019902; GO:0021794; GO:0030275; GO:0030424; GO:0030426; GO:0031175; GO:0033555; GO:0034109; GO:0042220; GO:0042734; GO:0043005; GO:0043025; GO:0043209; GO:0045211; GO:0048666; GO:0050804; GO:0050850; GO:0051930; GO:0060045; GO:0060548; GO:0071679; GO:0098685; GO:0098978; GO:2001260 49713 XM_044320770.1 118 29 86 90 215 NA NA NA NA NA NA 49714 XM_044316228.1 32 0 0 6 0 NA NA NA NA NA NA 49715 XM_044325204.1 154 135 61 95 100 NA NA NA NA NA NA 49716 XM_029352583.2 0 6 0 0 26 NA NA NA NA NA NA 49717 XM_044314541.1 6058 5279 3417 6018 1377 NA NA NA NA NA NA 49718 XM_029348351.2 3871 2150 1913 3618 2737 NA NA NA NA NA NA 49719 XM_029331889.2 192 136 125 111 296 NA NA NA NA NA NA 49720 XM_029335482.2 77 166 114 159 153 NA NA NA NA NA NA 49721 XM_029346587.2 2161 3490 1445 2238 1432 Q5RE15 4.24e-97 26S proteasome non-ATPase regulatory subunit 8 (26S proteasome regulatory subunit RPN12) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) proteolysis [GO:0006508] GO:0005838; GO:0006508; GO:0022624 49722 XM_029338679.2 234 53 73 217 92 Q91YL3 0 Uridine-cytidine kinase-like 1 (EC 2.7.1.48) Mus musculus (Mouse) phosphorylation [GO:0016310]; UMP salvage [GO:0044206] GO:0004849; GO:0005524; GO:0005634; GO:0005737; GO:0016310; GO:0044206 49723 XR_006391273.1 12 44 4 147 129 NA NA NA NA NA NA 49724 XM_029344187.2 509 1205 708 253 346 NA NA NA NA NA NA 49725 XM_044313185.1 6 7 6 5 1 NA NA NA NA NA NA 49726 XR_006392860.1 0 0 2 52 1 NA NA NA NA NA NA 49727 XM_029357333.2 349 181 161 350 184 P36544 4.01e-71 Neuronal acetylcholine receptor subunit alpha-7 Homo sapiens (Human) acetylcholine receptor signaling pathway [GO:0095500]; calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; cognition [GO:0050890]; dendrite arborization [GO:0140059]; dendritic spine organization [GO:0097061]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; learning or memory [GO:0007611]; membrane depolarization [GO:0051899]; memory [GO:0007613]; modulation of excitatory postsynaptic potential [GO:0098815]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of tumor necrosis factor production [GO:0032720]; nervous system process [GO:0050877]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of CoA-transferase activity [GO:1905920]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; regulation of amyloid fibril formation [GO:1905906]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of membrane potential [GO:0042391]; regulation of neuron death [GO:1901214]; regulation of nitric oxide metabolic process [GO:0080164]; response to acetylcholine [GO:1905144]; response to amyloid-beta [GO:1904645]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; sensory processing [GO:0050893]; short-term memory [GO:0007614]; signal transduction [GO:0007165]; synapse organization [GO:0050808]; synaptic transmission, cholinergic [GO:0007271] GO:0001540; GO:0001666; GO:0001934; GO:0005216; GO:0005231; GO:0005262; GO:0005886; GO:0005892; GO:0006811; GO:0006816; GO:0006874; GO:0007165; GO:0007268; GO:0007271; GO:0007611; GO:0007613; GO:0007614; GO:0008284; GO:0015464; GO:0015643; GO:0016020; GO:0017081; GO:0022848; GO:0030594; GO:0032720; GO:0034220; GO:0035094; GO:0042166; GO:0042391; GO:0042803; GO:0043005; GO:0043410; GO:0044853; GO:0045202; GO:0045211; GO:0045766; GO:0050808; GO:0050877; GO:0050890; GO:0050893; GO:0051247; GO:0051899; GO:0070374; GO:0080164; GO:0095500; GO:0097061; GO:0098794; GO:0098815; GO:0140059; GO:1900273; GO:1901214; GO:1902004; GO:1902430; GO:1902991; GO:1904315; GO:1904645; GO:1905144; GO:1905906; GO:1905920; GO:2000463 49728 XR_006393320.1 26 15 15 17 82 NA NA NA NA NA NA 49729 XM_044319462.1 97 35 19 84 74 P0CI65 9.5e-48 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 49730 XM_044319462.1 97 35 19 84 74 P0CI65 1.32e-45 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 49731 XM_044319462.1 97 35 19 84 74 P0CI65 2.55e-45 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 49732 XM_044319462.1 97 35 19 84 74 P0CI65 1.45e-41 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 49733 XM_044319462.1 97 35 19 84 74 P0CI65 1.04e-40 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 49734 XM_044319462.1 97 35 19 84 74 P0CI65 3.48e-40 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 49735 XM_044319462.1 97 35 19 84 74 P0CI65 1.51e-38 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 49736 XM_044319462.1 97 35 19 84 74 P0CI65 2.76e-37 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 49737 XM_044319462.1 97 35 19 84 74 P0CI65 1.01e-29 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 49738 XR_006393085.1 12 3 32 0 12 NA NA NA NA NA NA 49739 XM_044315423.1 635 125 90 356 180 NA NA NA NA NA NA 49740 XM_029350833.2 957 1231 619 895 895 O43818 6.67e-155 U3 small nucleolar RNA-interacting protein 2 (RRP9 homolog) (U3 small nucleolar ribonucleoprotein-associated 55 kDa protein) (U3 snoRNP-associated 55 kDa protein) (U3-55K) Homo sapiens (Human) rRNA processing [GO:0006364] GO:0003723; GO:0005654; GO:0005730; GO:0006364; GO:0030515; GO:0031428; GO:0032040; GO:0034511 49741 XM_029332320.2 6113 5111 2758 4219 3244 P60522 3.3e-61 Gamma-aminobutyric acid receptor-associated protein-like 2 (GABA(A) receptor-associated protein-like 2) (Ganglioside expression factor 2) (GEF-2) (Golgi-associated ATPase enhancer of 16 kDa) (GATE-16) Rattus norvegicus (Rat) autophagosome assembly [GO:0000045]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; macroautophagy [GO:0016236]; negative regulation of proteasomal protein catabolic process [GO:1901799]; protein localization to endoplasmic reticulum [GO:0070972]; protein transport [GO:0015031] GO:0000045; GO:0000139; GO:0000421; GO:0000422; GO:0005737; GO:0005776; GO:0005789; GO:0005794; GO:0005829; GO:0006995; GO:0015031; GO:0016236; GO:0031410; GO:0031625; GO:0070972; GO:1901799 49742 XM_044322459.1 586 427 40 253 214 Q96AY4 3.58e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 49743 XM_044322459.1 586 427 40 253 214 Q96AY4 4.46e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 49744 XM_044322459.1 586 427 40 253 214 Q96AY4 5.19e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 49745 XM_044322459.1 586 427 40 253 214 Q96AY4 8.53e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 49746 XM_044322459.1 586 427 40 253 214 Q96AY4 1.41e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 49747 XM_029345647.2 11 15 0 3 30 NA NA NA NA NA NA 49748 XM_029339581.2 0 61 0 8 0 NA NA NA NA NA NA 49749 XM_029357016.2 5 0 4 2 7 NA NA NA NA NA NA 49750 XM_029329741.2 125 254 298 65 0 NA NA NA NA NA NA 49751 XM_044326277.1 102 30 18 43 42 Q09575 2.58e-32 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 49752 XR_003826062.2 0 1 0 0 31 NA NA NA NA NA NA 49753 XM_044309943.1 224 91 137 8 222 P18433 6.72e-133 Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (EC 3.1.3.48) Homo sapiens (Human) insulin receptor signaling pathway [GO:0008286]; integrin-mediated signaling pathway [GO:0007229]; modulation of chemical synaptic transmission [GO:0050804]; protein dephosphorylation [GO:0006470]; protein phosphorylation [GO:0006468]; regulation of focal adhesion assembly [GO:0051893] GO:0004725; GO:0005001; GO:0005886; GO:0005925; GO:0006468; GO:0006470; GO:0007229; GO:0008286; GO:0016020; GO:0043235; GO:0050804; GO:0051893; GO:0070062; GO:0097060; GO:0098685 49754 XR_003826869.2 0 0 6 4 2 NA NA NA NA NA NA 49755 XM_029336807.2 836 404 336 806 917 G3M4F8 3.89e-27 Octopamine receptor beta-2R (CsOA2B2) Chilo suppressalis (Asiatic rice borer moth) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cellular response to amine stimulus [GO:0071418]; octopamine signaling pathway [GO:0071927]; tyramine signaling pathway [GO:0071928] GO:0004989; GO:0005886; GO:0007189; GO:0008226; GO:0016020; GO:0071418; GO:0071927; GO:0071928 49756 XM_029336340.2 0 0 0 58 31 NA NA NA NA NA NA 49757 XR_006398028.1 58 20 41 203 218 NA NA NA NA NA NA 49758 XM_044317151.1 0 0 0 6 0 NA NA NA NA NA NA 49759 XM_044318965.1 154 110 114 69 188 O73853 4.84e-94 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Ictalurus punctatus (Channel catfish) (Silurus punctatus) steroid biosynthetic process [GO:0006694] GO:0004508; GO:0005506; GO:0006694; GO:0016020; GO:0020037; GO:0047442 49760 XM_044317367.1 225 0 1363 1424 785 Q96AY4 3.72e-115 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 49761 XM_044317367.1 225 0 1363 1424 785 Q96AY4 3.86e-114 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 49762 XM_044317367.1 225 0 1363 1424 785 Q96AY4 1.09e-113 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 49763 XM_044317367.1 225 0 1363 1424 785 Q96AY4 3.37e-84 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 49764 XM_044317367.1 225 0 1363 1424 785 Q96AY4 3.32e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 49765 XM_029326563.2 638 447 88 550 547 Q8N8A2 3.36e-35 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (PP6-ARS-B) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-B) (Ankyrin repeat domain-containing protein 44) Homo sapiens (Human) NA NA 49766 XM_029326563.2 638 447 88 550 547 Q8N8A2 1.5e-30 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (PP6-ARS-B) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-B) (Ankyrin repeat domain-containing protein 44) Homo sapiens (Human) NA NA 49767 XM_029326563.2 638 447 88 550 547 Q8N8A2 9.64e-28 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (PP6-ARS-B) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-B) (Ankyrin repeat domain-containing protein 44) Homo sapiens (Human) NA NA 49768 XM_029326563.2 638 447 88 550 547 Q8N8A2 2.41e-26 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (PP6-ARS-B) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-B) (Ankyrin repeat domain-containing protein 44) Homo sapiens (Human) NA NA 49769 XM_029326563.2 638 447 88 550 547 Q8N8A2 7.76e-21 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (PP6-ARS-B) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-B) (Ankyrin repeat domain-containing protein 44) Homo sapiens (Human) NA NA 49770 XM_044318805.1 978 847 555 1075 900 Q8IVV2 0 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 49771 XM_044318805.1 978 847 555 1075 900 Q8IVV2 0 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 49772 XM_044318805.1 978 847 555 1075 900 Q8IVV2 0 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 49773 XM_044318805.1 978 847 555 1075 900 Q8IVV2 0 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 49774 XM_044318805.1 978 847 555 1075 900 Q8IVV2 0 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 49775 XM_044318805.1 978 847 555 1075 900 Q8IVV2 1.7e-100 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 49776 XM_044318805.1 978 847 555 1075 900 Q8IVV2 1.35e-89 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 49777 XM_044318805.1 978 847 555 1075 900 Q8IVV2 3.09e-43 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 49778 XM_029336610.2 7 0 0 29 13 NA NA NA NA NA NA 49779 XM_044321194.1 12 22 115 164 152 P46825 2.7e-32 Kinesin light chain (KLC) Doryteuthis pealeii (Longfin inshore squid) (Loligo pealeii) NA GO:0005737; GO:0005871; GO:0005874 49780 XM_044321194.1 12 22 115 164 152 P46825 3.55e-24 Kinesin light chain (KLC) Doryteuthis pealeii (Longfin inshore squid) (Loligo pealeii) NA GO:0005737; GO:0005871; GO:0005874 49781 XM_044321194.1 12 22 115 164 152 P46825 5.47e-21 Kinesin light chain (KLC) Doryteuthis pealeii (Longfin inshore squid) (Loligo pealeii) NA GO:0005737; GO:0005871; GO:0005874 49782 XM_029329645.2 60 18 88 91 27 NA NA NA NA NA NA 49783 XM_044315073.1 6 0 0 0 0 NA NA NA NA NA NA 49784 XM_044309148.1 6 13 0 12 14 NA NA NA NA NA NA 49785 XM_044322275.1 441 213 192 247 218 Q5ZK62 8.33e-163 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 (Centaurin-beta-2) (Cnt-b2) Gallus gallus (Chicken) cellular response to nerve growth factor stimulus [GO:1990090]; endocytic recycling [GO:0032456] GO:0005096; GO:0010008; GO:0032456; GO:0046872; GO:1990090 49786 XM_044322275.1 441 213 192 247 218 Q5ZK62 8.22e-53 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 (Centaurin-beta-2) (Cnt-b2) Gallus gallus (Chicken) cellular response to nerve growth factor stimulus [GO:1990090]; endocytic recycling [GO:0032456] GO:0005096; GO:0010008; GO:0032456; GO:0046872; GO:1990090 49787 XR_006394943.1 0 0 0 19 0 NA NA NA NA NA NA 49788 XM_044318733.1 11 4 37 0 0 NA NA NA NA NA NA 49789 XM_044323932.1 116 9 21 56 105 NA NA NA NA NA NA 49790 XM_029345021.2 11 3 14 14 6 NA NA NA NA NA NA 49791 XM_044315120.1 2465 1368 624 1150 768 NA NA NA NA NA NA 49792 XR_006394144.1 5 10 2 0 0 NA NA NA NA NA NA 49793 XM_044322409.1 92 93 160 17 84 NA NA NA NA NA NA 49794 XM_029354181.2 152 8 0 195 16 Q29599 1.07e-40 2'-5'-oligoadenylate synthase 1 ((2-5')oligo(A) synthase 1) (2-5A synthase 1) (EC 2.7.7.84) (p42 OAS) Sus scrofa (Pig) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; regulation of ribonuclease activity [GO:0060700] GO:0001730; GO:0003725; GO:0005524; GO:0005576; GO:0005654; GO:0005737; GO:0005739; GO:0005783; GO:0005829; GO:0016020; GO:0045071; GO:0045087; GO:0046872; GO:0051607; GO:0060700 49795 XM_029329320.2 404 246 174 322 343 Q8CDK2 0 Cytosolic carboxypeptidase 2 (EC 3.4.17.-) (ATP/GTP-binding protein-like 2) (Protein deglutamylase CCP2) Mus musculus (Mouse) protein side chain deglutamylation [GO:0035610]; proteolysis [GO:0006508] GO:0004181; GO:0005814; GO:0005829; GO:0006508; GO:0008270; GO:0035610; GO:0036064 49796 XM_029346134.2 514 379 178 424 10 NA NA NA NA NA NA 49797 XM_029325035.2 32 11 106 110 17 NA NA NA NA NA NA 49798 XR_006394514.1 49 26 13 1 8 NA NA NA NA NA NA 49799 XM_029356463.2 104 0 191 32 330 Q9VQ37 1.44e-86 Mitochondrial carrier protein Rim2 Drosophila melanogaster (Fruit fly) cellular respiration [GO:0045333]; deoxynucleotide transport [GO:0030302]; locomotion [GO:0040011]; mitochondrial genome maintenance [GO:0000002]; mitochondrial transcription [GO:0006390]; mitochondrial transport [GO:0006839]; mitochondrion distribution [GO:0048311]; mitochondrion organization [GO:0007005]; pyrimidine nucleotide import into mitochondrion [GO:1990519] GO:0000002; GO:0005739; GO:0005743; GO:0006390; GO:0006839; GO:0007005; GO:0015218; GO:0030302; GO:0040011; GO:0045333; GO:0048311; GO:1990519 49800 XM_029348134.2 4175 3182 2392 3839 3657 C3YWU0 0 Alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucoside fucohydrolase) Branchiostoma floridae (Florida lancelet) (Amphioxus) fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139] GO:0004560; GO:0005576; GO:0005764; GO:0006004; GO:0016139 49801 XM_029331441.2 613 426 316 341 732 NA NA NA NA NA NA 49802 XR_006396480.1 16 1 425 0 11 NA NA NA NA NA NA 49803 XM_029351406.2 222 0 0 515 237 NA NA NA NA NA NA 49804 XM_044327950.1 10 1 0 0 4 NA NA NA NA NA NA 49805 XM_029349369.2 0 0 0 0 98 O60683 3.73e-54 Peroxisome biogenesis factor 10 (EC 2.3.2.27) (Peroxin-10) (Peroxisomal biogenesis factor 10) (Peroxisome assembly protein 10) (RING finger protein 69) Homo sapiens (Human) peroxisome organization [GO:0007031]; protein import into peroxisome matrix [GO:0016558]; protein import into peroxisome matrix, receptor recycling [GO:0016562] GO:0005777; GO:0005778; GO:0007031; GO:0008022; GO:0008270; GO:0016558; GO:0016562; GO:0046872; GO:0061630 49806 XM_044316905.1 33 107 169 354 107 Q3ZBK2 2.68e-54 Peroxiredoxin-like 2A (Peroxiredoxin-like 2 activated in M-CSF stimulated monocytes) (Protein PAMM) (Redox-regulatory protein FAM213A) Bos taurus (Bovine) regulation of osteoclast differentiation [GO:0045670] GO:0005576; GO:0005737; GO:0016209; GO:0045670 49807 XM_029331848.2 186 277 348 890 224 Q5RJA1 0 DNA-binding protein RFX6 (Regulatory factor X 6) Danio rerio (Zebrafish) (Brachydanio rerio) endocrine pancreas development [GO:0031018]; glucose homeostasis [GO:0042593]; pancreatic A cell differentiation [GO:0003310]; pancreatic D cell differentiation [GO:0003311]; pancreatic epsilon cell differentiation [GO:0090104]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of insulin secretion [GO:0050796]; regulation of transcription by RNA polymerase II [GO:0006357]; type B pancreatic cell differentiation [GO:0003309] GO:0000976; GO:0000978; GO:0000981; GO:0003309; GO:0003310; GO:0003311; GO:0005634; GO:0006357; GO:0031018; GO:0035774; GO:0042593; GO:0045893; GO:0045944; GO:0050796; GO:0090104 49808 XM_029354097.2 46 10 7 7 15 Q91175 2.87e-47 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (MAR1) Oryzias latipes (Japanese rice fish) (Japanese killifish) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of vasoconstriction [GO:0045907] GO:0001996; GO:0004930; GO:0004937; GO:0005886; GO:0007200; GO:0007204; GO:0007267; GO:0043410; GO:0045907; GO:0071880 49809 XM_029348488.2 92 76 53 125 209 NA NA NA NA NA NA 49810 XM_029344595.2 1000 641 467 683 602 Q5I047 6.04e-60 ATP synthase subunit C lysine N-methyltransferase (EC 2.1.1.-) (Protein N-lysine methyltransferase FAM173B) Xenopus laevis (African clawed frog) peptidyl-lysine methylation [GO:0018022]; peptidyl-lysine trimethylation [GO:0018023]; positive regulation of proton-transporting ATP synthase activity, rotational mechanism [GO:1905273]; positive regulation of sensory perception of pain [GO:1904058]; regulation of mitochondrial ATP synthesis coupled proton transport [GO:1905706] GO:0005739; GO:0016279; GO:0018022; GO:0018023; GO:0030061; GO:1904058; GO:1905273; GO:1905706 49811 XM_044317238.1 88 118 135 85 53 NA NA NA NA NA NA 49812 XM_044307847.1 15 15 0 3 14 P04323 2.23e-44 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 49813 XM_044311959.1 8 0 0 0 2 NA NA NA NA NA NA 49814 XM_029328659.2 3 0 7 4 8 Q8HYJ7 6.33e-42 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5 (EC 2.4.1.152) (3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT5) (EC 2.4.1.65) (Fucosyltransferase 5) (Fucosyltransferase V) (Fuc-TV) (FucT-V) (Galactoside 3-L-fucosyltransferase) Gorilla gorilla gorilla (Western lowland gorilla) ceramide metabolic process [GO:0006672]; fucosylation [GO:0036065]; oligosaccharide metabolic process [GO:0009311]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493] GO:0006487; GO:0006493; GO:0006672; GO:0009311; GO:0017060; GO:0017083; GO:0032580; GO:0036065; GO:0046920 49815 XM_029330480.2 3080 2239 1808 2942 3455 Q5ZIQ3 2.16e-38 Heterogeneous nuclear ribonucleoprotein K (hnRNP K) Gallus gallus (Chicken) mRNA processing [GO:0006397]; negative regulation of DNA-templated transcription [GO:0045892]; regulation of gene expression [GO:0010468]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA splicing [GO:0008380] GO:0000785; GO:0003677; GO:0003729; GO:0005634; GO:0005654; GO:0005681; GO:0005737; GO:0006357; GO:0006397; GO:0008380; GO:0010468; GO:0045892; GO:0048024; GO:1990904 49816 XM_029330480.2 3080 2239 1808 2942 3455 Q5ZIQ3 5.34e-28 Heterogeneous nuclear ribonucleoprotein K (hnRNP K) Gallus gallus (Chicken) mRNA processing [GO:0006397]; negative regulation of DNA-templated transcription [GO:0045892]; regulation of gene expression [GO:0010468]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA splicing [GO:0008380] GO:0000785; GO:0003677; GO:0003729; GO:0005634; GO:0005654; GO:0005681; GO:0005737; GO:0006357; GO:0006397; GO:0008380; GO:0010468; GO:0045892; GO:0048024; GO:1990904 49817 XR_006396174.1 11 10 5 10 21 NA NA NA NA NA NA 49818 XM_029341962.2 20 138 212 368 252 P98070 5.84e-21 Bone morphogenetic protein 1 (BMP-1) (EC 3.4.24.-) Xenopus laevis (African clawed frog) cartilage development [GO:0051216]; cell differentiation [GO:0030154]; ossification [GO:0001503]; proteolysis [GO:0006508] GO:0001503; GO:0004222; GO:0005125; GO:0005509; GO:0005615; GO:0005794; GO:0006508; GO:0008083; GO:0008270; GO:0030154; GO:0051216 49819 XR_006391791.1 12 0 3 2 26 NA NA NA NA NA NA 49820 XM_029355708.2 21 59 113 0 0 P28818 9.33e-172 Ras-specific guanine nucleotide-releasing factor 1 (Ras-GRF1) (Guanine nucleotide-releasing protein) (GNRP) (P140 Ras-GRF) Rattus norvegicus (Rat) activation of GTPase activity [GO:0090630]; cell population proliferation [GO:0008283]; cellular response to antibiotic [GO:0071236]; cellular response to insulin stimulus [GO:0032869]; neuron projection development [GO:0031175]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of GTPase activity [GO:0043547]; positive regulation of Ras protein signal transduction [GO:0046579]; Ras protein signal transduction [GO:0007265]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of NMDA receptor activity [GO:2000310]; regulation of Rac protein signal transduction [GO:0035020]; regulation of Ras protein signal transduction [GO:0046578]; regulation of synaptic plasticity [GO:0048167]; response to amphetamine [GO:0001975]; response to endoplasmic reticulum stress [GO:0034976]; type B pancreatic cell proliferation [GO:0044342] GO:0001975; GO:0005085; GO:0005096; GO:0005737; GO:0005829; GO:0005886; GO:0007265; GO:0008022; GO:0008283; GO:0016323; GO:0016327; GO:0019901; GO:0030426; GO:0030971; GO:0031175; GO:0031267; GO:0032869; GO:0034976; GO:0035020; GO:0035254; GO:0043025; GO:0043547; GO:0044342; GO:0046578; GO:0046579; GO:0048146; GO:0048167; GO:0048168; GO:0071236; GO:0090630; GO:0097440; GO:2000310 49821 XM_029355708.2 21 59 113 0 0 P28818 6.17e-100 Ras-specific guanine nucleotide-releasing factor 1 (Ras-GRF1) (Guanine nucleotide-releasing protein) (GNRP) (P140 Ras-GRF) Rattus norvegicus (Rat) activation of GTPase activity [GO:0090630]; cell population proliferation [GO:0008283]; cellular response to antibiotic [GO:0071236]; cellular response to insulin stimulus [GO:0032869]; neuron projection development [GO:0031175]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of GTPase activity [GO:0043547]; positive regulation of Ras protein signal transduction [GO:0046579]; Ras protein signal transduction [GO:0007265]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of NMDA receptor activity [GO:2000310]; regulation of Rac protein signal transduction [GO:0035020]; regulation of Ras protein signal transduction [GO:0046578]; regulation of synaptic plasticity [GO:0048167]; response to amphetamine [GO:0001975]; response to endoplasmic reticulum stress [GO:0034976]; type B pancreatic cell proliferation [GO:0044342] GO:0001975; GO:0005085; GO:0005096; GO:0005737; GO:0005829; GO:0005886; GO:0007265; GO:0008022; GO:0008283; GO:0016323; GO:0016327; GO:0019901; GO:0030426; GO:0030971; GO:0031175; GO:0031267; GO:0032869; GO:0034976; GO:0035020; GO:0035254; GO:0043025; GO:0043547; GO:0044342; GO:0046578; GO:0046579; GO:0048146; GO:0048167; GO:0048168; GO:0071236; GO:0090630; GO:0097440; GO:2000310 49822 XM_044307940.1 104 151 67 0 96 NA NA NA NA NA NA 49823 XM_029355464.2 932 257 507 567 1031 O15229 8.02e-165 Kynurenine 3-monooxygenase (EC 1.14.13.9) (Kynurenine 3-hydroxylase) Homo sapiens (Human) 'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; aging [GO:0007568]; anthranilate metabolic process [GO:0043420]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; kynurenic acid biosynthetic process [GO:0034276]; kynurenine metabolic process [GO:0070189]; L-kynurenine metabolic process [GO:0097052]; NAD metabolic process [GO:0019674]; positive regulation of glutamate secretion, neurotransmission [GO:1903296]; positive regulation of neuron death [GO:1901216]; quinolinate biosynthetic process [GO:0019805]; response to salt stress [GO:0009651]; tryptophan catabolic process [GO:0006569] GO:0004502; GO:0005615; GO:0005741; GO:0005829; GO:0006569; GO:0007568; GO:0009651; GO:0016174; GO:0019674; GO:0019805; GO:0034276; GO:0034354; GO:0043420; GO:0050660; GO:0070189; GO:0071222; GO:0071347; GO:0071949; GO:0097052; GO:1901216; GO:1903296 49824 XM_044320653.1 0 0 0 0 11 Q09575 3.97e-32 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 49825 XM_029329220.2 0 18 8 0 53 Q9U6A0 2.37e-59 Sodium/potassium/calcium exchanger Nckx30C (Na(+)/K(+)/Ca(2+)-exchange protein Nckx30C) Drosophila melanogaster (Fruit fly) calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; compound eye development [GO:0048749]; sodium ion transport [GO:0006814] GO:0005262; GO:0005886; GO:0006814; GO:0006816; GO:0006874; GO:0008273; GO:0015293; GO:0016020; GO:0048749; GO:0070588 49826 XR_006398008.1 977 1019 358 366 559 Q498M4 3.75e-83 WD repeat-containing protein 5 Rattus norvegicus (Rat) gluconeogenesis [GO:0006094]; histone H3 acetylation [GO:0043966]; histone H3-K14 acetylation [GO:0044154]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; negative regulation of histone H3-K4 methylation [GO:0051572]; neuron projection development [GO:0031175]; peptidyl-lysine methylation [GO:0018022]; positive regulation of gluconeogenesis [GO:0045722]; positive regulation of histone H3-K4 methylation [GO:0051571]; regulation of cell cycle [GO:0051726]; regulation of cell division [GO:0051302]; regulation of DNA-templated transcription [GO:0006355]; regulation of dosage compensation by inactivation of X chromosome [GO:1900095]; regulation of embryonic development [GO:0045995]; regulation of histone deacetylation [GO:0031063]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tubulin deacetylation [GO:0090043]; skeletal system development [GO:0001501]; transcription initiation-coupled chromatin remodeling [GO:0045815] GO:0000123; GO:0001501; GO:0005634; GO:0006094; GO:0006355; GO:0006357; GO:0018022; GO:0031063; GO:0031175; GO:0035064; GO:0035097; GO:0042393; GO:0042800; GO:0043966; GO:0043981; GO:0043982; GO:0043984; GO:0044154; GO:0044545; GO:0044665; GO:0044666; GO:0045722; GO:0045815; GO:0045995; GO:0048188; GO:0051302; GO:0051568; GO:0051571; GO:0051572; GO:0051726; GO:0071339; GO:0090043; GO:0140672; GO:1900095 49827 XR_006398008.1 977 1019 358 366 559 Q498M4 3.75e-83 WD repeat-containing protein 5 Rattus norvegicus (Rat) gluconeogenesis [GO:0006094]; histone H3 acetylation [GO:0043966]; histone H3-K14 acetylation [GO:0044154]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; negative regulation of histone H3-K4 methylation [GO:0051572]; neuron projection development [GO:0031175]; peptidyl-lysine methylation [GO:0018022]; positive regulation of gluconeogenesis [GO:0045722]; positive regulation of histone H3-K4 methylation [GO:0051571]; regulation of cell cycle [GO:0051726]; regulation of cell division [GO:0051302]; regulation of DNA-templated transcription [GO:0006355]; regulation of dosage compensation by inactivation of X chromosome [GO:1900095]; regulation of embryonic development [GO:0045995]; regulation of histone deacetylation [GO:0031063]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tubulin deacetylation [GO:0090043]; skeletal system development [GO:0001501]; transcription initiation-coupled chromatin remodeling [GO:0045815] GO:0000123; GO:0001501; GO:0005634; GO:0006094; GO:0006355; GO:0006357; GO:0018022; GO:0031063; GO:0031175; GO:0035064; GO:0035097; GO:0042393; GO:0042800; GO:0043966; GO:0043981; GO:0043982; GO:0043984; GO:0044154; GO:0044545; GO:0044665; GO:0044666; GO:0045722; GO:0045815; GO:0045995; GO:0048188; GO:0051302; GO:0051568; GO:0051571; GO:0051572; GO:0051726; GO:0071339; GO:0090043; GO:0140672; GO:1900095 49828 XM_044316980.1 1 0 5 0 40 NA NA NA NA NA NA 49829 XM_029330557.2 317 220 383 429 384 Q9WYJ1 8.53e-47 NA NA NA NA 49830 XM_029351520.2 703 0 0 298 388 Q05BQ1 2.88e-48 Protein turtle homolog A (Dendrite arborization and synapse maturation protein 1) (Immunoglobulin superfamily member 9A) (IgSF9A) Mus musculus (Mouse) cell-cell adhesion [GO:0098609]; dendrite development [GO:0016358]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; regulation of synapse organization [GO:0050807] GO:0005886; GO:0007156; GO:0016358; GO:0030424; GO:0030425; GO:0050807; GO:0060077; GO:0098609; GO:0098632 49831 XM_044326980.1 36 10 27 38 55 P0CT39 3.93e-57 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 49832 XM_044326980.1 36 10 27 38 55 P0CT39 3.93e-57 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 49833 XM_044326980.1 36 10 27 38 55 P0CT39 3.93e-57 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 49834 XM_029330503.2 406 256 48 450 344 Q8IPH9 1.55e-57 Slowpoke-binding protein Drosophila melanogaster (Fruit fly) modulation of chemical synaptic transmission [GO:0050804]; negative regulation of ATP-dependent activity [GO:0032780]; negative regulation of ion transport [GO:0043271]; neuromuscular synaptic transmission [GO:0007274]; regulation of membrane potential [GO:0042391]; response to starvation [GO:0042594] GO:0004672; GO:0005737; GO:0005886; GO:0007274; GO:0032780; GO:0042391; GO:0042594; GO:0043271; GO:0045202; GO:0050804 49835 XM_029340519.2 857 1107 414 672 686 Q9CX00 4.54e-59 IST1 homolog (Charged multivesicular body protein 8) (CHMP8) Mus musculus (Mouse) abscission [GO:0009838]; cell division [GO:0051301]; collateral sprouting [GO:0048668]; cytoskeleton-dependent cytokinesis [GO:0061640]; establishment of protein localization [GO:0045184]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of proteolysis [GO:0045862]; protein localization [GO:0008104]; protein transport [GO:0015031]; viral capsid secondary envelopment [GO:0046745]; viral release from host cell [GO:0019076] GO:0000785; GO:0005635; GO:0005793; GO:0005813; GO:0005829; GO:0008104; GO:0009838; GO:0015031; GO:0019076; GO:0019904; GO:0030496; GO:0031410; GO:0042802; GO:0043231; GO:0044877; GO:0045184; GO:0045862; GO:0046745; GO:0048668; GO:0048672; GO:0051301; GO:0061640; GO:0070062; GO:0090541; GO:0090543 49836 XR_003827824.2 50 2 35 8 16 NA NA NA NA NA NA 49837 XM_044320995.1 131 0 0 0 107 A6QLU6 2.41e-22 Adhesion G-protein coupled receptor D1 (G-protein coupled receptor 133) Bos taurus (Bovine) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0005886; GO:0007166; GO:0007186; GO:0007189 49838 XM_029344720.2 127 64 70 64 127 NA NA NA NA NA NA 49839 XM_044320706.1 0 0 0 0 8 NA NA NA NA NA NA 49840 XM_044323293.1 26 0 0 28 14 Q5R5U3 6.15e-83 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 49841 XM_044323293.1 26 0 0 28 14 Q5R5U3 1.61e-82 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 49842 XM_044323293.1 26 0 0 28 14 Q5R5U3 1.06e-78 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 49843 XM_044323293.1 26 0 0 28 14 Q5R5U3 6.45e-78 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 49844 XM_044323293.1 26 0 0 28 14 Q5R5U3 1.34e-71 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 49845 XM_044323293.1 26 0 0 28 14 Q5R5U3 8.79e-62 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 49846 XM_044323293.1 26 0 0 28 14 Q5R5U3 2.78e-60 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 49847 XM_029333967.2 8 0 0 5 14 NA NA NA NA NA NA 49848 XM_044328051.1 12735 19916 9198 8547 9037 NA NA NA NA NA NA 49849 XM_029340126.2 332 402 237 1812 977 Q9WUJ8 1.96e-38 Origin recognition complex subunit 6 Mus musculus (Mouse) DNA replication initiation [GO:0006270]; DNA-templated DNA replication [GO:0006261]; negative regulation of cell division [GO:0051782] GO:0000808; GO:0001650; GO:0003677; GO:0005654; GO:0005664; GO:0006261; GO:0006270; GO:0051782 49850 XR_006396675.1 1 0 0 33 0 NA NA NA NA NA NA 49851 XM_029356917.2 12226 11096 8810 13182 13810 Q9DA39 1.08e-80 Protein lifeguard 4 (Transmembrane BAX inhibitor motif-containing protein 4) (Z-protein) Mus musculus (Mouse) apoptotic process [GO:0006915]; locomotory behavior [GO:0007626]; negative regulation of apoptotic process [GO:0043066]; negative regulation of neuron apoptotic process [GO:0043524]; regulation of calcium-mediated signaling [GO:0050848] GO:0000139; GO:0005795; GO:0006915; GO:0007626; GO:0016020; GO:0043066; GO:0043524; GO:0050848 49852 XM_044325890.1 195 196 311 217 35 P48506 0 Glutamate--cysteine ligase catalytic subunit (EC 6.3.2.2) (GCS heavy chain) (Gamma-ECS) (Gamma-glutamylcysteine synthetase) Homo sapiens (Human) aging [GO:0007568]; blood vessel diameter maintenance [GO:0097746]; cell redox homeostasis [GO:0045454]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to glucose stimulus [GO:0071333]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to insulin stimulus [GO:0032869]; cellular response to mechanical stimulus [GO:0071260]; cellular response to thyroxine stimulus [GO:0097069]; cysteine metabolic process [GO:0006534]; glutamate metabolic process [GO:0006536]; glutathione biosynthetic process [GO:0006750]; L-ascorbic acid metabolic process [GO:0019852]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of hepatic stellate cell activation [GO:2000490]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; regulation of mitochondrial depolarization [GO:0051900]; response to activity [GO:0014823]; response to arsenic-containing substance [GO:0046685]; response to cadmium ion [GO:0046686]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to human chorionic gonadotropin [GO:0044752]; response to interleukin-1 [GO:0070555]; response to nitrosative stress [GO:0051409]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to xenobiotic stimulus [GO:0009410] GO:0000287; GO:0004357; GO:0005524; GO:0005739; GO:0005829; GO:0006534; GO:0006536; GO:0006750; GO:0006979; GO:0007568; GO:0007584; GO:0009408; GO:0009410; GO:0009725; GO:0014823; GO:0016595; GO:0017109; GO:0019852; GO:0031397; GO:0032436; GO:0032869; GO:0035729; GO:0043066; GO:0043524; GO:0043531; GO:0044344; GO:0044752; GO:0044877; GO:0045454; GO:0045892; GO:0046685; GO:0046686; GO:0051409; GO:0051900; GO:0070555; GO:0071260; GO:0071333; GO:0071372; GO:0097069; GO:0097746; GO:1901029; GO:2000490; GO:2001237 49853 XR_006394707.1 504 339 196 510 456 P14272 7.92e-52 Plasma kallikrein (EC 3.4.21.34) (Fletcher factor) (Kininogenin) (Plasma prekallikrein) [Cleaved into: Plasma kallikrein heavy chain; Plasma kallikrein light chain] Rattus norvegicus (Rat) blood coagulation, intrinsic pathway [GO:0007597]; fibrinolysis [GO:0042730]; inflammatory response [GO:0006954]; liver regeneration [GO:0097421]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]; proteolysis [GO:0006508]; zymogen activation [GO:0031638] GO:0004252; GO:0005615; GO:0006508; GO:0006954; GO:0007597; GO:0031638; GO:0031639; GO:0042730; GO:0051919; GO:0097421 49854 XR_006394707.1 504 339 196 510 456 P14272 4.84e-31 Plasma kallikrein (EC 3.4.21.34) (Fletcher factor) (Kininogenin) (Plasma prekallikrein) [Cleaved into: Plasma kallikrein heavy chain; Plasma kallikrein light chain] Rattus norvegicus (Rat) blood coagulation, intrinsic pathway [GO:0007597]; fibrinolysis [GO:0042730]; inflammatory response [GO:0006954]; liver regeneration [GO:0097421]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]; proteolysis [GO:0006508]; zymogen activation [GO:0031638] GO:0004252; GO:0005615; GO:0006508; GO:0006954; GO:0007597; GO:0031638; GO:0031639; GO:0042730; GO:0051919; GO:0097421 49855 XR_006394707.1 504 339 196 510 456 P14272 4.84e-31 Plasma kallikrein (EC 3.4.21.34) (Fletcher factor) (Kininogenin) (Plasma prekallikrein) [Cleaved into: Plasma kallikrein heavy chain; Plasma kallikrein light chain] Rattus norvegicus (Rat) blood coagulation, intrinsic pathway [GO:0007597]; fibrinolysis [GO:0042730]; inflammatory response [GO:0006954]; liver regeneration [GO:0097421]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]; proteolysis [GO:0006508]; zymogen activation [GO:0031638] GO:0004252; GO:0005615; GO:0006508; GO:0006954; GO:0007597; GO:0031638; GO:0031639; GO:0042730; GO:0051919; GO:0097421 49856 XM_029339219.2 1396 1515 799 1248 846 Q5TYW6 1.53e-99 Radial spoke head protein 9 homolog Danio rerio (Zebrafish) (Brachydanio rerio) axonemal central apparatus assembly [GO:1904158]; axoneme assembly [GO:0035082]; cilium assembly [GO:0060271]; cilium movement [GO:0003341]; cilium movement involved in cell motility [GO:0060294]; motile cilium assembly [GO:0044458]; radial spoke assembly [GO:0062177] GO:0001534; GO:0003341; GO:0005929; GO:0005930; GO:0031514; GO:0035082; GO:0044458; GO:0060091; GO:0060271; GO:0060294; GO:0062177; GO:1904158 49857 XM_029355706.2 406 480 237 480 103 NA NA NA NA NA NA 49858 XM_029332462.1 1077 871 649 776 950 Q8R0A0 4.97e-68 General transcription factor IIF subunit 2 (Transcription initiation factor IIF subunit beta) (TFIIF-beta) Mus musculus (Mouse) positive regulation of transcription by RNA polymerase II [GO:0045944]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription by RNA polymerase II [GO:0006366]; transcription elongation by RNA polymerase II promoter [GO:0006368]; transcription initiation at RNA polymerase II promoter [GO:0006367] GO:0003677; GO:0005634; GO:0005654; GO:0005674; GO:0005675; GO:0006366; GO:0006367; GO:0006368; GO:0015630; GO:0016251; GO:0045944; GO:0051123; GO:0097550 49859 XM_029341244.2 4 0 16 1 59 NA NA NA NA NA NA 49860 XM_044312870.1 241 245 187 241 385 P54644 3.19e-66 RAC family serine/threonine-protein kinase homolog (EC 2.7.11.1) Dictyostelium discoideum (Social amoeba) bleb assembly [GO:0032060]; chemotaxis to cAMP [GO:0043327]; culmination involved in sorocarp development [GO:0031154]; establishment of cell polarity [GO:0030010]; establishment or maintenance of cell polarity [GO:0007163]; intracellular signal transduction [GO:0035556]; macropinocytosis [GO:0044351]; maintenance of cell polarity [GO:0030011]; mitotic cytokinesis [GO:0000281]; myosin II filament assembly [GO:0031036]; negative regulation of phagocytosis [GO:0050765]; negative regulation of Ras protein signal transduction [GO:0046580]; peptidyl-serine phosphorylation [GO:0018105]; phagosome maturation [GO:0090382]; phosphatidylinositol-mediated signaling [GO:0048015]; polyphosphate-mediated signaling [GO:0110094]; positive regulation of chemorepellent activity [GO:1903669]; positive regulation of macropinocytosis [GO:1905303]; protein phosphorylation [GO:0006468]; pseudopodium assembly [GO:0031269]; regulation of cell migration [GO:0030334]; regulation of chemotaxis [GO:0050920]; response to differentiation-inducing factor 1 [GO:1903013]; response to hydrogen peroxide [GO:0042542] GO:0000281; GO:0004674; GO:0004691; GO:0005524; GO:0005547; GO:0005829; GO:0005886; GO:0005938; GO:0006468; GO:0007163; GO:0018105; GO:0019887; GO:0030010; GO:0030011; GO:0030295; GO:0030334; GO:0031036; GO:0031154; GO:0031252; GO:0031269; GO:0032060; GO:0035556; GO:0042542; GO:0043327; GO:0044351; GO:0046580; GO:0048015; GO:0050765; GO:0050920; GO:0090382; GO:0106310; GO:0110094; GO:1903013; GO:1903669; GO:1905303 49861 XM_044323273.1 3 4 3 2 6 Q9VBW3 4.27e-58 Tyrosine kinase receptor Cad96Ca (EC 2.7.10.1) (Cadherin-96Ca) (Tyrosine kinase receptor HD-14) Drosophila melanogaster (Fruit fly) calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; Golgi organization [GO:0007030]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell size [GO:0045792]; positive regulation of kinase activity [GO:0033674]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060] GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005886; GO:0006468; GO:0007030; GO:0007156; GO:0007169; GO:0014068; GO:0016339; GO:0033674; GO:0042060; GO:0043235; GO:0045177; GO:0045792; GO:0090303 49862 XM_029358495.2 90 42 38 83 96 Q6PF45 5.67e-63 Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Solute carrier family 32 member 1) (Vesicular GABA transporter) (xVIAAT) Xenopus laevis (African clawed frog) beta-alanine transport [GO:0001762]; gamma-aminobutyric acid import [GO:0051939]; gamma-aminobutyric acid transport [GO:0015812]; glycine transport [GO:0015816]; neurotransmitter transport [GO:0006836] GO:0001762; GO:0006836; GO:0008021; GO:0015185; GO:0015187; GO:0015812; GO:0015816; GO:0030659; GO:0042995; GO:0051939; GO:0098793; GO:0140799; GO:0140800 49863 XR_006396000.1 0 6 23 8 123 Q91ZV3 2.08e-21 Discoidin, CUB and LCCL domain-containing protein 2 (Endothelial and smooth muscle cell-derived neuropilin-like protein) Mus musculus (Mouse) negative regulation of cell growth [GO:0030308]; wound healing [GO:0042060] GO:0005886; GO:0009986; GO:0030308; GO:0038023; GO:0042060 49864 XM_044316332.1 14 7 12 44 37 NA NA NA NA NA NA 49865 XM_029349947.2 64 111 113 128 154 Q2T9J0 2.91e-42 Peroxisomal leader peptide-processing protease (EC 3.4.21.-) (Trypsin domain-containing protein 1) [Cleaved into: Peroxisomal leader peptide-processing protease, 15 kDa form; Peroxisomal leader peptide-processing protease, 45 kDa form] Homo sapiens (Human) protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of fatty acid beta-oxidation [GO:0031998] GO:0002020; GO:0004252; GO:0005777; GO:0005782; GO:0005829; GO:0006508; GO:0016020; GO:0016485; GO:0031998; GO:0042802 49866 XM_044318471.1 5 416 20 14 20 NA NA NA NA NA NA 49867 XM_029330251.2 50 27 43 37 26 Q6GPB8 2.56e-152 Lariat debranching enzyme A (EC 3.1.4.-) Xenopus laevis (African clawed frog) mRNA processing [GO:0006397]; RNA splicing, via transesterification reactions [GO:0000375] GO:0000375; GO:0005634; GO:0006397; GO:0008419 49868 XM_044315512.1 5 12 0 13 0 Q96AY4 1.04e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 49869 XM_029341359.2 203 60 210 575 352 Q9UTA8 6.68e-24 Uncharacterized methyltransferase-like C25B8.10 (EC 2.1.1.-) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) cellular detoxification [GO:1990748]; methylation [GO:0032259] GO:0005634; GO:0005829; GO:0008168; GO:0032259; GO:0046547; GO:1990748 49870 XM_029357066.2 70 0 0 0 16 NA NA NA NA NA NA 49871 XM_044325260.1 2896 2549 1745 2050 2004 Q9PT60 2.83e-58 RalA-binding protein 1-A (RalBP1-A) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase) (EC 7.6.2.2, EC 7.6.2.3) (Ral-interacting protein) (Ral-interacting protein 1-A) (RIP1-A) (XRLIP2) (XRLIP76-A) Xenopus laevis (African clawed frog) actin cytoskeleton organization [GO:0030036]; gastrulation with mouth forming second [GO:0001702]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of protein phosphorylation [GO:0001934]; regulation of Cdc42 protein signal transduction [GO:0032489]; small GTPase mediated signal transduction [GO:0007264] GO:0000922; GO:0001702; GO:0001934; GO:0005096; GO:0005524; GO:0005634; GO:0005739; GO:0005829; GO:0005886; GO:0007264; GO:0008559; GO:0015431; GO:0016020; GO:0030027; GO:0030036; GO:0031267; GO:0032489; GO:0090141 49872 XM_044318727.1 292 264 100 405 278 Q3SYS4 6.8e-99 Dynein axonemal assembly factor 1 (Leucine-rich repeat-containing protein 50) Bos taurus (Bovine) cilium assembly [GO:0060271] GO:0005930; GO:0060271; GO:0070840 49873 XM_029348173.2 765 551 417 640 731 Q9USQ7 2.21e-106 Diphthine--ammonia ligase (EC 6.3.1.14) (Diphthamide synthase) (Diphthamide synthetase) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) meiotic cell cycle [GO:0051321]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]; regulation of cytoplasmic translation [GO:2000765] GO:0005524; GO:0005634; GO:0005829; GO:0017178; GO:0017183; GO:0051321; GO:2000765 49874 XM_044329051.1 837 506 659 726 988 NA NA NA NA NA NA 49875 XM_029331453.2 395 208 182 275 274 Q8N3Y7 4.57e-77 Epidermal retinol dehydrogenase 2 (EPHD-2) (RDH-E2) (EC 1.1.1.105) (Retinal short-chain dehydrogenase reductase 2) (retSDR2) (Short-chain dehydrogenase/reductase family 16C member 5) Homo sapiens (Human) keratinocyte proliferation [GO:0043616]; negative regulation of histone acetylation [GO:0035067]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of histone deacetylation [GO:0031065]; retinal metabolic process [GO:0042574]; retinol metabolic process [GO:0042572] GO:0000122; GO:0003714; GO:0004745; GO:0005634; GO:0005789; GO:0005811; GO:0016616; GO:0017053; GO:0031065; GO:0035067; GO:0042572; GO:0042574; GO:0043616; GO:0061629; GO:0140297 49876 XM_029325333.2 266 0 72 202 224 NA NA NA NA NA NA 49877 XM_029358750.2 6789 8609 3945 6132 4244 NA NA NA NA NA NA 49878 XR_006392077.1 71 72 42 51 103 NA NA NA NA NA NA 49879 XM_044308572.1 0 45 47 38 326 NA NA NA NA NA NA 49880 XM_029343164.2 393 578 259 349 551 Q96KE9 2.11e-74 BTB/POZ domain-containing protein 6 (Lens BTB domain protein) Homo sapiens (Human) neurogenesis [GO:0022008] GO:0005829; GO:0022008 49881 XM_029338294.2 4743 1593 1458 2198 3785 Q6P5H6 6.46e-94 FERM domain-containing protein 5 Mus musculus (Mouse) actomyosin structure organization [GO:0031032]; negative regulation of cell motility [GO:2000146]; positive regulation of cell adhesion [GO:0045785]; regulation of cell migration [GO:0030334] GO:0005178; GO:0005856; GO:0005912; GO:0008092; GO:0019901; GO:0030334; GO:0031032; GO:0045785; GO:2000146 49882 XM_044316739.1 694 310 295 342 111 Q9H4G4 2.54e-21 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Homo sapiens (Human) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070062; GO:0070374 49883 XR_006393343.1 29 14 26 21 13 NA NA NA NA NA NA 49884 XM_029343358.2 150 145 114 127 157 NA NA NA NA NA NA 49885 XR_003827327.2 96 62 58 35 81 NA NA NA NA NA NA 49886 XR_006394268.1 11 4 43 9 189 NA NA NA NA NA NA 49887 XR_003826265.2 1038 3233 394 1517 1166 NA NA NA NA NA NA 49888 XM_044325853.1 39 20 8 10 31 NA NA NA NA NA NA 49889 XM_029334744.2 3056 2367 1496 3644 2961 Q91924 4.69e-68 Zinc finger protein SNAI2 (Protein slug-alpha) (Protein snail homolog 2) (Snail protein homolog Slug) (xSlu) Xenopus laevis (African clawed frog) neural crest cell fate specification [GO:0014036]; neural crest cell migration [GO:0001755]; neural crest formation [GO:0014029] GO:0001755; GO:0003677; GO:0005634; GO:0014029; GO:0014036; GO:0046872 49890 XM_044326090.1 0 2 0 0 18 NA NA NA NA NA NA 49891 XM_029346604.2 53 0 0 10 0 NA NA NA NA NA NA 49892 XM_029347654.2 0 12 0 0 4 Q0EEE2 1.85e-68 Patched domain-containing protein 3 (RND-type protein RNDEu-3) Mus musculus (Mouse) NA GO:0005783; GO:0005789; GO:0005886; GO:0016020; GO:0097225 49893 XM_029340114.2 30 2 2 6 49 NA NA NA NA NA NA 49894 XM_044327819.1 0 143 0 1 13 NA NA NA NA NA NA 49895 XM_044325661.1 96 35 46 22 23 NA NA NA NA NA NA 49896 XM_029351359.2 2563 1726 1289 3059 1897 NA NA NA NA NA NA 49897 XM_044325722.1 361 143 205 233 285 Q8TDM6 7.13e-60 Disks large homolog 5 (Discs large protein P-dlg) (Placenta and prostate DLG) Homo sapiens (Human) apical protein localization [GO:0045176]; cell-cell adhesion [GO:0098609]; epithelial to mesenchymal transition [GO:0001837]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; intracellular signal transduction [GO:0035556]; maintenance of cell polarity [GO:0030011]; metanephric collecting duct development [GO:0072205]; midbrain development [GO:0030901]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of hippo signaling [GO:0035331]; negative regulation of T cell proliferation [GO:0042130]; neuroepithelial cell differentiation [GO:0060563]; polarized epithelial cell differentiation [GO:0030859]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of hippo signaling [GO:0035332]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of synapse assembly [GO:0051965]; postsynapse organization [GO:0099173]; protein localization to adherens junction [GO:0071896]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; signal transduction [GO:0007165]; zonula adherens assembly [GO:0045186] GO:0001837; GO:0005737; GO:0005886; GO:0005912; GO:0007165; GO:0008013; GO:0008092; GO:0008285; GO:0014069; GO:0030011; GO:0030054; GO:0030159; GO:0030336; GO:0030859; GO:0030901; GO:0035331; GO:0035332; GO:0035556; GO:0036064; GO:0042130; GO:0042981; GO:0045176; GO:0045186; GO:0045197; GO:0045880; GO:0051965; GO:0060441; GO:0060563; GO:0060999; GO:0065003; GO:0071896; GO:0072205; GO:0098609; GO:0098978; GO:0099173 49898 XM_044325722.1 361 143 205 233 285 Q8TDM6 9.98e-25 Disks large homolog 5 (Discs large protein P-dlg) (Placenta and prostate DLG) Homo sapiens (Human) apical protein localization [GO:0045176]; cell-cell adhesion [GO:0098609]; epithelial to mesenchymal transition [GO:0001837]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; intracellular signal transduction [GO:0035556]; maintenance of cell polarity [GO:0030011]; metanephric collecting duct development [GO:0072205]; midbrain development [GO:0030901]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of hippo signaling [GO:0035331]; negative regulation of T cell proliferation [GO:0042130]; neuroepithelial cell differentiation [GO:0060563]; polarized epithelial cell differentiation [GO:0030859]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of hippo signaling [GO:0035332]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of synapse assembly [GO:0051965]; postsynapse organization [GO:0099173]; protein localization to adherens junction [GO:0071896]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; signal transduction [GO:0007165]; zonula adherens assembly [GO:0045186] GO:0001837; GO:0005737; GO:0005886; GO:0005912; GO:0007165; GO:0008013; GO:0008092; GO:0008285; GO:0014069; GO:0030011; GO:0030054; GO:0030159; GO:0030336; GO:0030859; GO:0030901; GO:0035331; GO:0035332; GO:0035556; GO:0036064; GO:0042130; GO:0042981; GO:0045176; GO:0045186; GO:0045197; GO:0045880; GO:0051965; GO:0060441; GO:0060563; GO:0060999; GO:0065003; GO:0071896; GO:0072205; GO:0098609; GO:0098978; GO:0099173 49899 XM_044320867.1 6487 7811 3752 8370 4453 NA NA NA NA NA NA 49900 XM_029329032.2 1287 2836 1278 3289 2405 Q6DFF6 1.26e-165 Kelch-like protein 20 Xenopus laevis (African clawed frog) Golgi to endosome transport [GO:0006895]; negative regulation of apoptotic process [GO:0043066]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K33-linked ubiquitination [GO:1990390]; protein transport [GO:0015031]; protein ubiquitination [GO:0016567] GO:0004842; GO:0005737; GO:0005802; GO:0005829; GO:0006895; GO:0015031; GO:0016567; GO:0016605; GO:0019964; GO:0031463; GO:0043066; GO:0043161; GO:0048471; GO:1990390 49901 XM_029329032.2 1287 2836 1278 3289 2405 Q6DFF6 3.08e-23 Kelch-like protein 20 Xenopus laevis (African clawed frog) Golgi to endosome transport [GO:0006895]; negative regulation of apoptotic process [GO:0043066]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K33-linked ubiquitination [GO:1990390]; protein transport [GO:0015031]; protein ubiquitination [GO:0016567] GO:0004842; GO:0005737; GO:0005802; GO:0005829; GO:0006895; GO:0015031; GO:0016567; GO:0016605; GO:0019964; GO:0031463; GO:0043066; GO:0043161; GO:0048471; GO:1990390 49902 XM_029339566.2 8 0 0 5 1 NA NA NA NA NA NA 49903 XM_044309575.1 13 124 2 3 113 NA NA NA NA NA NA 49904 XM_044321101.1 8 21 19 16 34 Q90632 5.08e-35 Monocarboxylate transporter 3 (MCT 3) (Retinal epithelial membrane protein) (Solute carrier family 16 member 8) Gallus gallus (Chicken) monocarboxylic acid transport [GO:0015718] GO:0005886; GO:0008028; GO:0015293; GO:0015718; GO:0016020; GO:0016323 49905 XR_006397702.1 178 81 111 181 292 NA NA NA NA NA NA 49906 XR_003823982.2 0 20 44 27 12 NA NA NA NA NA NA 49907 XM_044317317.1 57 5 22 16 128 Q8AV58 3.89e-80 Protein sidekick-1 Gallus gallus (Chicken) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; retina layer formation [GO:0010842]; synapse assembly [GO:0007416] GO:0005886; GO:0007156; GO:0007416; GO:0010842; GO:0042802; GO:0045202 49908 XM_044317317.1 57 5 22 16 128 Q8AV58 5.52e-72 Protein sidekick-1 Gallus gallus (Chicken) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; retina layer formation [GO:0010842]; synapse assembly [GO:0007416] GO:0005886; GO:0007156; GO:0007416; GO:0010842; GO:0042802; GO:0045202 49909 XM_044317317.1 57 5 22 16 128 Q8AV58 1.08e-67 Protein sidekick-1 Gallus gallus (Chicken) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; retina layer formation [GO:0010842]; synapse assembly [GO:0007416] GO:0005886; GO:0007156; GO:0007416; GO:0010842; GO:0042802; GO:0045202 49910 XM_044317317.1 57 5 22 16 128 Q8AV58 8.24e-65 Protein sidekick-1 Gallus gallus (Chicken) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; retina layer formation [GO:0010842]; synapse assembly [GO:0007416] GO:0005886; GO:0007156; GO:0007416; GO:0010842; GO:0042802; GO:0045202 49911 XM_044317317.1 57 5 22 16 128 Q8AV58 5.94e-62 Protein sidekick-1 Gallus gallus (Chicken) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; retina layer formation [GO:0010842]; synapse assembly [GO:0007416] GO:0005886; GO:0007156; GO:0007416; GO:0010842; GO:0042802; GO:0045202 49912 XM_044317317.1 57 5 22 16 128 Q8AV58 9.37e-33 Protein sidekick-1 Gallus gallus (Chicken) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; retina layer formation [GO:0010842]; synapse assembly [GO:0007416] GO:0005886; GO:0007156; GO:0007416; GO:0010842; GO:0042802; GO:0045202 49913 XM_044319942.1 298 248 222 312 731 O34313 9.59e-36 Trifunctional nucleotide phosphoesterase protein YfkN [Includes: 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase (EC 3.1.3.6) (EC 3.1.4.16); 5'-nucleotidase (EC 3.1.3.5)] Bacillus subtilis (strain 168) nucleotide catabolic process [GO:0009166] GO:0000166; GO:0005576; GO:0008254; GO:0008663; GO:0009166; GO:0030288; GO:0046872; GO:0106411 49914 XM_029343176.2 491 510 282 866 569 Q8IYE0 0 Coiled-coil domain-containing protein 146 Homo sapiens (Human) NA GO:0005737; GO:0005814; GO:0005856 49915 XM_029326898.2 2146 1018 412 1953 2079 Q5XJQ5 6.32e-125 Exosome complex component RRP45 (Exosome component 9) Danio rerio (Zebrafish) (Brachydanio rerio) exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear mRNA surveillance [GO:0071028]; nuclear polyadenylation-dependent mRNA catabolic process [GO:0071042]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; rRNA catabolic process [GO:0016075]; U1 snRNA 3'-end processing [GO:0034473]; U4 snRNA 3'-end processing [GO:0034475]; U5 snRNA 3'-end processing [GO:0034476] GO:0000176; GO:0000177; GO:0000467; GO:0003723; GO:0005654; GO:0005730; GO:0016075; GO:0034427; GO:0034473; GO:0034475; GO:0034476; GO:0043928; GO:0071028; GO:0071035; GO:0071038; GO:0071042 49916 XM_029346103.2 2863 3647 1449 1973 1862 Q3Y4E2 1.78e-116 Selenoprotein N (SePN) (SelN) Danio rerio (Zebrafish) (Brachydanio rerio) calcium ion homeostasis [GO:0055074]; calcium-mediated signaling [GO:0019722]; muscle cell development [GO:0055001]; muscle tissue development [GO:0060537]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; skeletal muscle fiber development [GO:0048741] GO:0005789; GO:0016491; GO:0019722; GO:0048741; GO:0055001; GO:0055074; GO:0060314; GO:0060537 49917 XM_029350884.2 957 729 422 869 554 NA NA NA NA NA NA 49918 XM_044328422.1 167 91 31 0 146 Q3UP23 1.96e-24 Transmembrane protein 26 Mus musculus (Mouse) NA GO:0016020 49919 XM_044323691.1 13 4 2 0 0 P10978 3.3e-33 Retrovirus-related Pol polyprotein from transposon TNT 1-94 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Nicotiana tabacum (Common tobacco) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0008270; GO:0015074 49920 XM_029349883.2 9293 10495 3454 8069 7188 O75347 1.59e-29 Tubulin-specific chaperone A (TCP1-chaperonin cofactor A) (Tubulin-folding cofactor A) (CFA) Homo sapiens (Human) post-chaperonin tubulin folding pathway [GO:0007023]; protein folding [GO:0006457]; tubulin complex assembly [GO:0007021] GO:0003723; GO:0005730; GO:0005737; GO:0005874; GO:0006457; GO:0007021; GO:0007023; GO:0015630; GO:0015631; GO:0048487; GO:0051087 49921 XR_006391378.1 486 184 173 993 743 NA NA NA NA NA NA 49922 XM_029347390.2 766 1092 455 420 365 Q9Y619 8.76e-97 Mitochondrial ornithine transporter 1 (Solute carrier family 25 member 15) Homo sapiens (Human) L-arginine transmembrane transport [GO:1903826]; L-lysine transmembrane transport [GO:1903401]; mitochondrial L-ornithine transmembrane transport [GO:1990575]; urea cycle [GO:0000050] GO:0000050; GO:0000064; GO:0005739; GO:0005743; GO:0015189; GO:0015297; GO:0016020; GO:0022857; GO:0061459; GO:1903401; GO:1903826; GO:1990575 49923 XM_044312149.1 0 0 6 0 2 NA NA NA NA NA NA 49924 XM_029338091.2 222 205 183 224 272 P16610 2.99e-32 Substance-K receptor (SKR) (NK-2 receptor) (NK-2R) (Neurokinin A receptor) (Tachykinin receptor 2) Rattus norvegicus (Rat) intestine smooth muscle contraction [GO:0014827]; negative regulation of luteinizing hormone secretion [GO:0033685]; operant conditioning [GO:0035106]; positive regulation of acetylcholine secretion, neurotransmission [GO:0014057]; positive regulation of flagellated sperm motility [GO:1902093]; positive regulation of ion transport [GO:0043270]; positive regulation of uterine smooth muscle contraction [GO:0070474]; positive regulation of vascular permeability [GO:0043117]; prolactin secretion [GO:0070459]; regulation of uterine smooth muscle contraction [GO:0070472]; response to electrical stimulus [GO:0051602] GO:0004995; GO:0005886; GO:0014057; GO:0014827; GO:0016020; GO:0016497; GO:0033685; GO:0035106; GO:0036126; GO:0043117; GO:0043270; GO:0051602; GO:0061827; GO:0070459; GO:0070472; GO:0070474; GO:0097225; GO:1902093 49925 XM_044311640.1 32 27 21 29 12 Q96AY4 1.26e-77 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 49926 XM_044311640.1 32 27 21 29 12 Q96AY4 3.12e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 49927 XM_044311640.1 32 27 21 29 12 Q96AY4 5.02e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 49928 XM_044311640.1 32 27 21 29 12 Q96AY4 2.42e-71 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 49929 XM_044311640.1 32 27 21 29 12 Q96AY4 1.28e-66 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 49930 XM_044311640.1 32 27 21 29 12 Q96AY4 2.84e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 49931 XM_044311640.1 32 27 21 29 12 Q96AY4 5.28e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 49932 XM_044311640.1 32 27 21 29 12 Q96AY4 6.48e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 49933 XM_044321048.1 40 7 33 25 73 Q80XJ3 7.13e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 49934 XR_003828180.2 24 1 15 0 0 NA NA NA NA NA NA 49935 XM_029331497.2 562 409 328 413 474 NA NA NA NA NA NA 49936 XM_044310834.1 0 23 0 0 0 NA NA NA NA NA NA 49937 XR_006395698.1 321 114 110 204 103 NA NA NA NA NA NA 49938 XM_044326990.1 220 616 132 148 288 B2RRL2 5.73e-116 Jerky protein homolog-like Mus musculus (Mouse) NA GO:0003677; GO:0005634 49939 XM_044326517.1 4 8 8 11 17 Q6DGA6 1.02e-85 Allantoicase (EC 3.5.3.4) (Allantoate amidinohydrolase) Danio rerio (Zebrafish) (Brachydanio rerio) allantoin catabolic process [GO:0000256]; purine nucleobase metabolic process [GO:0006144] GO:0000256; GO:0004037; GO:0006144 49940 XM_029356393.2 0 181 58 0 94 Q6ZR37 3.91e-84 Pleckstrin homology domain-containing family G member 7 (PH domain-containing family G member 7) Homo sapiens (Human) Rho protein signal transduction [GO:0007266] GO:0005085; GO:0007266 49941 XM_044319239.1 0 0 0 3605 406 NA NA NA NA NA NA 49942 XM_044311502.1 0 68 37 0 81 Q6P2Y2 0 Dynein assembly factor with WDR repeat domains 1 (Outer row dynein assembly protein 16 homolog) (WD repeat-containing protein 69) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005929 49943 XM_044311502.1 0 68 37 0 81 Q6P2Y2 1.74e-40 Dynein assembly factor with WDR repeat domains 1 (Outer row dynein assembly protein 16 homolog) (WD repeat-containing protein 69) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005929 49944 XM_029335413.2 274 398 255 271 279 O60566 1.01e-64 Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (hBUBR1) (Mitotic checkpoint kinase MAD3L) (Protein SSK1) Homo sapiens (Human) apoptotic process [GO:0006915]; cell division [GO:0051301]; meiotic sister chromatid cohesion, centromeric [GO:0051754]; metaphase/anaphase transition of mitotic cell cycle [GO:0007091]; mitotic spindle assembly checkpoint signaling [GO:0007094]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; phosphorylation [GO:0016310]; protein localization to chromosome, centromeric region [GO:0071459] GO:0000776; GO:0000940; GO:0004672; GO:0004674; GO:0005524; GO:0005680; GO:0005737; GO:0005815; GO:0005819; GO:0005829; GO:0006915; GO:0007091; GO:0007094; GO:0016310; GO:0033597; GO:0048471; GO:0051301; GO:0051444; GO:0051754; GO:0071459; GO:0106310 49945 XM_029350825.2 438 256 156 631 57 Q5MPA9 6.39e-171 Serine/threonine-protein kinase DCLK2 (EC 2.7.11.1) (CaMK-like CREB regulatory kinase 2) (CL2) (CLICK-II) (CLICK2) (Doublecortin-like and CAM kinase-like 2) (Doublecortin-like kinase 2) Rattus norvegicus (Rat) hippocampus development [GO:0021766]; intracellular signal transduction [GO:0035556]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of protein localization to nucleus [GO:1900181]; peptidyl-serine phosphorylation [GO:0018105]; protein localization to nucleus [GO:0034504]; pyramidal neuron development [GO:0021860] GO:0000226; GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0005856; GO:0008017; GO:0018105; GO:0021766; GO:0021860; GO:0034504; GO:0035556; GO:0106310; GO:1900181 49946 XM_044324642.1 52 21 40 56 12 P18460 4.1e-84 Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (Tyrosine kinase receptor CEK2) Gallus gallus (Chicken) apoptotic process [GO:0006915]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0004714; GO:0005007; GO:0005524; GO:0005886; GO:0006915; GO:0007169; GO:0008284; GO:0017134; GO:0033674; GO:0043235; GO:0043410 49947 XM_029352743.2 173 59 0 124 0 Q9H0J9 2.25e-23 Protein mono-ADP-ribosyltransferase PARP12 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 12) (ARTD12) (Poly [ADP-ribose] polymerase 12) (PARP-12) (Zinc finger CCCH domain-containing protein 1) Homo sapiens (Human) protein auto-ADP-ribosylation [GO:0070213] GO:0003723; GO:0003950; GO:0005634; GO:0016779; GO:0046872; GO:0070213; GO:0140803; GO:1990404 49948 XM_044317166.1 2147 261 26 432 299 B8WI85 0 Uncharacterized skeletal organic matrix protein 7 (Uncharacterized SOMP-7) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 49949 XM_044317166.1 2147 261 26 432 299 B8WI85 4.69e-29 Uncharacterized skeletal organic matrix protein 7 (Uncharacterized SOMP-7) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 49950 XM_044316340.1 7 0 3 15 5 P81274 1.13e-33 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 49951 XM_044316340.1 7 0 3 15 5 P81274 1.63e-33 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 49952 XM_044316340.1 7 0 3 15 5 P81274 5.11e-26 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 49953 XM_044316340.1 7 0 3 15 5 P81274 2.58e-21 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 49954 XM_044313447.1 0 0 0 53 0 NA NA NA NA NA NA 49955 XM_044329172.1 0 18 21 10 42 NA NA NA NA NA NA 49956 XM_044321270.1 25 0 0 29 30 NA NA NA NA NA NA 49957 XM_029336909.2 0 476 0 285 254 Q765P7 7.67e-59 Protein MTSS 2 (Actin-bundling with BAIAP2 homology protein 1) (ABBA-1) (MTSS1-like protein) Homo sapiens (Human) activation of GTPase activity [GO:0090630]; cell projection assembly [GO:0030031]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; lamellipodium organization [GO:0097581]; membrane organization [GO:0061024]; plasma membrane organization [GO:0007009] GO:0003779; GO:0003785; GO:0005096; GO:0005543; GO:0005546; GO:0007009; GO:0009898; GO:0015629; GO:0030027; GO:0030031; GO:0030864; GO:0031267; GO:0032587; GO:0036120; GO:0061024; GO:0090630; GO:0097581 49958 XM_044324674.1 359 251 335 482 576 Q96AY4 5.67e-112 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 49959 XM_044324674.1 359 251 335 482 576 Q96AY4 1.37e-110 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 49960 XM_044324674.1 359 251 335 482 576 Q96AY4 6.84e-108 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 49961 XM_044324674.1 359 251 335 482 576 Q96AY4 8.34e-108 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 49962 XM_044324674.1 359 251 335 482 576 Q96AY4 4.65e-106 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 49963 XM_044324674.1 359 251 335 482 576 Q96AY4 4.47e-101 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 49964 XM_044324674.1 359 251 335 482 576 Q96AY4 7.16e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 49965 XR_006391435.1 97 0 33 37 150 NA NA NA NA NA NA 49966 XM_044315385.1 0 0 8 19 32 NA NA NA NA NA NA 49967 XR_006394838.1 112 41 59 101 105 NA NA NA NA NA NA 49968 XM_029352309.2 803 1500 431 1198 912 Q6P7Q4 2.2e-81 Lactoylglutathione lyase (EC 4.4.1.5) (Aldoketomutase) (Glyoxalase I) (Glx I) (Ketone-aldehyde mutase) (Methylglyoxalase) (S-D-lactoylglutathione methylglyoxal lyase) Rattus norvegicus (Rat) carbohydrate metabolic process [GO:0005975]; glutathione metabolic process [GO:0006749]; methylglyoxal metabolic process [GO:0009438]; negative regulation of apoptotic process [GO:0043066]; osteoclast differentiation [GO:0030316]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0004462; GO:0005654; GO:0005829; GO:0005886; GO:0005975; GO:0006357; GO:0006749; GO:0008270; GO:0009438; GO:0030316; GO:0043066 49969 XM_029333096.2 661 557 379 596 524 Q9Y3B8 4.43e-81 Oligoribonuclease, mitochondrial (EC 3.1.15.-) (RNA exonuclease 2 homolog) (Small fragment nuclease) Homo sapiens (Human) nucleobase-containing compound metabolic process [GO:0006139]; nucleotide metabolic process [GO:0009117] GO:0000175; GO:0000287; GO:0003676; GO:0005634; GO:0005730; GO:0005737; GO:0005739; GO:0005758; GO:0005759; GO:0005925; GO:0006139; GO:0008296; GO:0008408; GO:0009117 49970 XM_044321940.1 0 12 30 25 91 NA NA NA NA NA NA 49971 XR_006396848.1 162 624 123 920 283 B8UU74 4.7e-23 Uncharacterized skeletal organic matrix protein 4 (Uncharacterized SOMP-4) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 49972 XR_006396848.1 162 624 123 920 283 B8UU74 4.7e-23 Uncharacterized skeletal organic matrix protein 4 (Uncharacterized SOMP-4) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 49973 XR_006398059.1 1 10 0 6 1 NA NA NA NA NA NA 49974 XM_029336696.2 65 0 0 11 0 NA NA NA NA NA NA 49975 XR_003824364.2 647 356 418 643 804 NA NA NA NA NA NA 49976 XM_029330420.2 47 0 0 10 5 Q9EQD2 9.09e-38 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 49977 XM_044308597.1 0 17 0 0 0 NA NA NA NA NA NA 49978 XM_029340623.2 27 116 101 387 0 Q7Z5V6 1.31e-68 Protein phosphatase 1 regulatory subunit 32 Homo sapiens (Human) NA GO:0005737; GO:0019902; GO:0036064 49979 XM_044316203.1 367 732 40 2 261 NA NA NA NA NA NA 49980 XM_029337971.2 270 884 328 513 467 O00339 1.44e-49 Matrilin-2 Homo sapiens (Human) extracellular matrix organization [GO:0030198] GO:0005201; GO:0005509; GO:0005576; GO:0030198; GO:0031012; GO:0062023; GO:0120216 49981 XM_029337971.2 270 884 328 513 467 O00339 9.59e-40 Matrilin-2 Homo sapiens (Human) extracellular matrix organization [GO:0030198] GO:0005201; GO:0005509; GO:0005576; GO:0030198; GO:0031012; GO:0062023; GO:0120216 49982 XM_029337971.2 270 884 328 513 467 O00339 8.22e-31 Matrilin-2 Homo sapiens (Human) extracellular matrix organization [GO:0030198] GO:0005201; GO:0005509; GO:0005576; GO:0030198; GO:0031012; GO:0062023; GO:0120216 49983 XM_029337971.2 270 884 328 513 467 O00339 1.33e-30 Matrilin-2 Homo sapiens (Human) extracellular matrix organization [GO:0030198] GO:0005201; GO:0005509; GO:0005576; GO:0030198; GO:0031012; GO:0062023; GO:0120216 49984 XM_029337971.2 270 884 328 513 467 O00339 3.82e-30 Matrilin-2 Homo sapiens (Human) extracellular matrix organization [GO:0030198] GO:0005201; GO:0005509; GO:0005576; GO:0030198; GO:0031012; GO:0062023; GO:0120216 49985 XM_029337971.2 270 884 328 513 467 O00339 3.05e-22 Matrilin-2 Homo sapiens (Human) extracellular matrix organization [GO:0030198] GO:0005201; GO:0005509; GO:0005576; GO:0030198; GO:0031012; GO:0062023; GO:0120216 49986 XM_029329398.2 214 113 81 109 124 Q8C8H8 5.95e-25 Kyphoscoliosis peptidase (EC 3.4.-.-) Mus musculus (Mouse) muscle organ development [GO:0007517]; neuromuscular junction development [GO:0007528]; proteolysis [GO:0006508] GO:0005737; GO:0005856; GO:0006508; GO:0007517; GO:0007528; GO:0008233; GO:0030018 49987 XM_029348261.2 580 318 417 287 268 Q711T7 0 Glutamine-dependent NAD(+) synthetase (EC 6.3.5.1) (NAD(+) synthase [glutamine-hydrolyzing]) (NAD(+) synthetase) (NH3-dependent NAD(+) synthetase-like protein) Mus musculus (Mouse) 'de novo' NAD biosynthetic process [GO:0034627]; NAD biosynthetic process [GO:0009435] GO:0003952; GO:0004359; GO:0005524; GO:0005737; GO:0008795; GO:0009435; GO:0034627 49988 XR_006392989.1 41 2 25 5 151 NA NA NA NA NA NA 49989 XM_029355402.2 68 10 53 42 24 NA NA NA NA NA NA 49990 XM_029351577.2 204 233 106 179 159 Q96M11 1.78e-22 Centriolar and ciliogenesis-associated protein HYLS1 (Hydrolethalus syndrome protein 1) Homo sapiens (Human) cilium assembly [GO:0060271] GO:0005634; GO:0005737; GO:0005813; GO:0005814; GO:0005829; GO:0005886; GO:0005929; GO:0060271; GO:0097730 49991 XM_029332410.2 169 197 146 141 164 Q91XU0 0 ATPase WRNIP1 (EC 3.6.1.-) (Werner helicase-interacting protein 1) Mus musculus (Mouse) DNA synthesis involved in DNA repair [GO:0000731]; DNA-templated DNA replication [GO:0006261]; innate immune response [GO:0045087]; regulation of DNA-templated DNA replication initiation [GO:0030174] GO:0000731; GO:0000781; GO:0003677; GO:0005524; GO:0005634; GO:0006261; GO:0008047; GO:0016887; GO:0017116; GO:0030174; GO:0042802; GO:0045087; GO:0046872; GO:0048471 49992 XM_044310580.1 17 32 13 84 48 NA NA NA NA NA NA 49993 XM_044318149.1 0 0 0 37 0 Q9NW07 2.98e-38 Zinc finger protein 358 Homo sapiens (Human) embryonic forelimb morphogenesis [GO:0035115]; neural tube development [GO:0021915]; regulation of transcription by RNA polymerase II [GO:0006357]; stem cell population maintenance [GO:0019827] GO:0000978; GO:0003700; GO:0005634; GO:0006357; GO:0019827; GO:0021915; GO:0035115; GO:0046872 49994 XM_044318149.1 0 0 0 37 0 Q9NW07 9.49e-37 Zinc finger protein 358 Homo sapiens (Human) embryonic forelimb morphogenesis [GO:0035115]; neural tube development [GO:0021915]; regulation of transcription by RNA polymerase II [GO:0006357]; stem cell population maintenance [GO:0019827] GO:0000978; GO:0003700; GO:0005634; GO:0006357; GO:0019827; GO:0021915; GO:0035115; GO:0046872 49995 XM_044318149.1 0 0 0 37 0 Q9NW07 2.48e-34 Zinc finger protein 358 Homo sapiens (Human) embryonic forelimb morphogenesis [GO:0035115]; neural tube development [GO:0021915]; regulation of transcription by RNA polymerase II [GO:0006357]; stem cell population maintenance [GO:0019827] GO:0000978; GO:0003700; GO:0005634; GO:0006357; GO:0019827; GO:0021915; GO:0035115; GO:0046872 49996 XM_044318149.1 0 0 0 37 0 Q9NW07 1.44e-26 Zinc finger protein 358 Homo sapiens (Human) embryonic forelimb morphogenesis [GO:0035115]; neural tube development [GO:0021915]; regulation of transcription by RNA polymerase II [GO:0006357]; stem cell population maintenance [GO:0019827] GO:0000978; GO:0003700; GO:0005634; GO:0006357; GO:0019827; GO:0021915; GO:0035115; GO:0046872 49997 XM_029340521.2 1541 597 406 830 882 Q8R4G6 1.21e-172 Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (EC 2.4.1.155) (Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase) (GlcNAc-T V) (GNT-V) (Mannoside acetylglucosaminyltransferase 5) (N-acetylglucosaminyl-transferase V) [Cleaved into: Secreted alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (Secreted beta-1,6-N-acetylglucosaminyltransferase V) (Secreted GNT-V)] Mus musculus (Mouse) negative regulation of protein tyrosine phosphatase activity [GO:1903614]; positive regulation of cell migration [GO:0030335]; positive regulation of receptor signaling pathway via STAT [GO:1904894]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279] GO:0000139; GO:0004864; GO:0005576; GO:0005794; GO:0006487; GO:0008375; GO:0016020; GO:0016757; GO:0018279; GO:0030144; GO:0030145; GO:0030335; GO:0043204; GO:1903614; GO:1904894 49998 XM_029339129.2 0 106 87 85 43 NA NA NA NA NA NA 49999 XM_044326526.1 4092 4236 4296 3462 2268 Q9Z2U1 2.11e-148 Proteasome subunit alpha type-5 (Macropain zeta chain) (Multicatalytic endopeptidase complex zeta chain) (Proteasome zeta chain) Mus musculus (Mouse) proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] GO:0000502; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005839; GO:0010498; GO:0019773; GO:0043161 50000 XM_044323693.1 43 8 0 0 5 NA NA NA NA NA NA 50001 XM_029356251.2 397 309 257 334 278 Q5I0K7 4.37e-54 UDP-N-acetylglucosamine transferase subunit ALG13 homolog (EC 2.4.1.141) (Glycosyltransferase 28 domain-containing protein 1) Rattus norvegicus (Rat) dolichol-linked oligosaccharide biosynthetic process [GO:0006488]; negative regulation of neuron death [GO:1901215]; negative regulation of TORC1 signaling [GO:1904262]; regulation of synaptic plasticity [GO:0048167] GO:0004577; GO:0005737; GO:0005783; GO:0006488; GO:0048167; GO:1901215; GO:1904262 50002 XM_029327673.2 44 16 32 12 59 NA NA NA NA NA NA 50003 XM_029350719.2 2524 2449 1658 1926 1102 Q6IMK3 2.1e-39 DnaJ homolog subfamily C member 27 (Rab and DnaJ domain-containing protein) Danio rerio (Zebrafish) (Brachydanio rerio) intracellular protein transport [GO:0006886] GO:0003924; GO:0005525; GO:0005634; GO:0006886 50004 XM_044308875.1 1817 3715 1894 31 7576 NA NA NA NA NA NA 50005 XR_006392557.1 9 0 0 1 4 NA NA NA NA NA NA 50006 XR_006394780.1 952 540 643 1003 1481 Q8WV93 4.29e-75 AFG1-like ATPase (Lactation elevated protein 1) (EC 3.6.-.-) (Protein AFG1 homolog) Homo sapiens (Human) mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial protein catabolic process [GO:0035694]; mitochondrion organization [GO:0007005] GO:0005524; GO:0005737; GO:0005739; GO:0006123; GO:0007005; GO:0016887; GO:0031966; GO:0035694 50007 XM_029347122.2 2 15 49 2 36 NA NA NA NA NA NA 50008 XM_044319458.1 9 0 3 3 20 NA NA NA NA NA NA 50009 XR_003824535.2 30 35 50 51 51 NA NA NA NA NA NA 50010 XM_044313489.1 3 0 0 0 36 NA NA NA NA NA NA 50011 XM_029331251.2 0 3 0 10 14 NA NA NA NA NA NA 50012 XM_044316902.1 0 66 13 115 17 Q3ZBK2 4.83e-53 Peroxiredoxin-like 2A (Peroxiredoxin-like 2 activated in M-CSF stimulated monocytes) (Protein PAMM) (Redox-regulatory protein FAM213A) Bos taurus (Bovine) regulation of osteoclast differentiation [GO:0045670] GO:0005576; GO:0005737; GO:0016209; GO:0045670 50013 XM_044327873.1 2402 1832 1641 2413 2800 A7Z064 0 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase) (EC 1.1.1.34) Bos taurus (Bovine) cholesterol biosynthetic process [GO:0006695]; coenzyme A metabolic process [GO:0015936]; isoprenoid biosynthetic process [GO:0008299]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein secretion [GO:0050709]; sterol biosynthetic process [GO:0016126]; visual learning [GO:0008542] GO:0004420; GO:0005778; GO:0005783; GO:0005789; GO:0006695; GO:0008299; GO:0008542; GO:0015936; GO:0016126; GO:0042177; GO:0043407; GO:0050709; GO:0070402; GO:0120225; GO:1900222 50014 XR_006397402.1 109 62 48 59 52 NA NA NA NA NA NA 50015 XM_044321660.1 21 47 27 72 27 Q7RTR2 7.57e-53 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 50016 XM_044318154.1 115 69 55 101 31 Q8K2J9 4.18e-66 BTB/POZ domain-containing protein 6 Mus musculus (Mouse) neurogenesis [GO:0022008] GO:0005829; GO:0022008 50017 XM_044314181.1 134 61 8 578 312 Q91287 2.36e-81 Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (PFR3) Pleurodeles waltl (Iberian ribbed newt) apoptotic process [GO:0006915]; positive regulation of cell population proliferation [GO:0008284] GO:0005007; GO:0005524; GO:0005886; GO:0006915; GO:0008284 50018 XM_044314181.1 134 61 8 578 312 Q91287 8.91e-68 Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (PFR3) Pleurodeles waltl (Iberian ribbed newt) apoptotic process [GO:0006915]; positive regulation of cell population proliferation [GO:0008284] GO:0005007; GO:0005524; GO:0005886; GO:0006915; GO:0008284 50019 XR_006392140.1 328 213 258 255 678 Q5RHH4 0 Intraflagellar transport protein 172 homolog Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; intraciliary transport [GO:0042073]; photoreceptor cell maintenance [GO:0045494]; pronephros development [GO:0048793]; regulation of TOR signaling [GO:0032006]; retina development in camera-type eye [GO:0060041] GO:0005929; GO:0005930; GO:0030992; GO:0032006; GO:0036064; GO:0042073; GO:0045494; GO:0048793; GO:0060041; GO:0060271 50020 XR_006392140.1 328 213 258 255 678 Q5RHH4 0 Intraflagellar transport protein 172 homolog Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; intraciliary transport [GO:0042073]; photoreceptor cell maintenance [GO:0045494]; pronephros development [GO:0048793]; regulation of TOR signaling [GO:0032006]; retina development in camera-type eye [GO:0060041] GO:0005929; GO:0005930; GO:0030992; GO:0032006; GO:0036064; GO:0042073; GO:0045494; GO:0048793; GO:0060041; GO:0060271 50021 XR_006392140.1 328 213 258 255 678 Q5RHH4 0 Intraflagellar transport protein 172 homolog Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; intraciliary transport [GO:0042073]; photoreceptor cell maintenance [GO:0045494]; pronephros development [GO:0048793]; regulation of TOR signaling [GO:0032006]; retina development in camera-type eye [GO:0060041] GO:0005929; GO:0005930; GO:0030992; GO:0032006; GO:0036064; GO:0042073; GO:0045494; GO:0048793; GO:0060041; GO:0060271 50022 XR_006392140.1 328 213 258 255 678 Q5RHH4 0 Intraflagellar transport protein 172 homolog Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; intraciliary transport [GO:0042073]; photoreceptor cell maintenance [GO:0045494]; pronephros development [GO:0048793]; regulation of TOR signaling [GO:0032006]; retina development in camera-type eye [GO:0060041] GO:0005929; GO:0005930; GO:0030992; GO:0032006; GO:0036064; GO:0042073; GO:0045494; GO:0048793; GO:0060041; GO:0060271 50023 XM_044322924.1 1931 1016 911 2841 2372 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 50024 XM_044322924.1 1931 1016 911 2841 2372 P07207 4.87e-179 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 50025 XM_044322924.1 1931 1016 911 2841 2372 P07207 6.12e-178 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 50026 XM_044322924.1 1931 1016 911 2841 2372 P07207 7.1e-168 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 50027 XM_044322924.1 1931 1016 911 2841 2372 P07207 1.14e-163 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 50028 XM_044322924.1 1931 1016 911 2841 2372 P07207 2.81e-151 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 50029 XM_044322924.1 1931 1016 911 2841 2372 P07207 9.1e-149 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 50030 XM_044322924.1 1931 1016 911 2841 2372 P07207 1.74e-141 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 50031 XM_044322924.1 1931 1016 911 2841 2372 P07207 5.61e-85 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 50032 XM_044322924.1 1931 1016 911 2841 2372 P07207 4.5e-73 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 50033 XM_044322924.1 1931 1016 911 2841 2372 P07207 1.99e-68 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 50034 XM_044322924.1 1931 1016 911 2841 2372 P07207 4.32e-68 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 50035 XM_044322924.1 1931 1016 911 2841 2372 P07207 4.66e-68 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 50036 XM_044322924.1 1931 1016 911 2841 2372 P07207 1.16e-65 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 50037 XM_044322924.1 1931 1016 911 2841 2372 P07207 5.81e-64 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 50038 XM_044322924.1 1931 1016 911 2841 2372 P07207 2.27e-60 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 50039 XM_044322924.1 1931 1016 911 2841 2372 P07207 2.97e-60 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 50040 XM_044322924.1 1931 1016 911 2841 2372 P07207 4.51e-43 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 50041 XM_044322924.1 1931 1016 911 2841 2372 P07207 1.96e-38 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 50042 XM_044322924.1 1931 1016 911 2841 2372 P07207 7.11e-31 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 50043 XM_044322924.1 1931 1016 911 2841 2372 P07207 3.44e-30 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 50044 XM_044322924.1 1931 1016 911 2841 2372 P07207 4.4e-24 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 50045 XM_044317108.1 27 59 35 75 95 NA NA NA NA NA NA 50046 XM_044327396.1 173 261 162 302 192 Q8R151 0 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 50047 XM_044327396.1 173 261 162 302 192 Q8R151 8.04e-85 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 50048 XM_044308516.1 21 8 51 18 43 NA NA NA NA NA NA 50049 XM_029327881.2 37 12 25 23 54 NA NA NA NA NA NA 50050 XM_029346581.2 509 1194 421 648 1549 NA NA NA NA NA NA 50051 XM_029337338.2 42 17 27 78 55 Q9PVX0 4.72e-40 Retinal homeobox protein Rx2 (cRax2) Gallus gallus (Chicken) positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0045944 50052 XM_029331252.2 163 557 305 94 76 P79888 2.23e-97 S-adenosylmethionine decarboxylase proenzyme (AdoMetDC) (SAMDC) (EC 4.1.1.50) [Cleaved into: S-adenosylmethionine decarboxylase alpha chain; S-adenosylmethionine decarboxylase beta chain] Xenopus laevis (African clawed frog) spermidine biosynthetic process [GO:0008295]; spermine biosynthetic process [GO:0006597] GO:0004014; GO:0006597; GO:0008295 50053 XM_029349277.2 296 139 78 173 187 A2RUV5 0 Probable ATP-dependent DNA helicase HFM1 (EC 3.6.4.12) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cellular component organization or biogenesis [GO:0071840]; meiotic cell cycle [GO:0051321] GO:0003676; GO:0004386; GO:0005524; GO:0016887; GO:0051321; GO:0071840 50054 XM_044323829.1 894 757 59 218 83 NA NA NA NA NA NA 50055 XR_006397531.1 0 12 0 0 0 NA NA NA NA NA NA 50056 XM_029326189.2 12 9 1 0 0 Q94887 4.69e-32 Neurexin-4 (Neurexin IV) Drosophila melanogaster (Fruit fly) axon ensheathment [GO:0008366]; cell adhesion involved in heart morphogenesis [GO:0061343]; cell-cell junction organization [GO:0045216]; dorsal closure [GO:0007391]; establishment of glial blood-brain barrier [GO:0060857]; heart process [GO:0003015]; nerve maturation [GO:0021682]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]; synaptic target recognition [GO:0008039]; terminal button organization [GO:0072553] GO:0003015; GO:0005886; GO:0005919; GO:0007391; GO:0008039; GO:0008104; GO:0008366; GO:0019991; GO:0021682; GO:0035151; GO:0045202; GO:0045216; GO:0048786; GO:0060857; GO:0061343; GO:0072553; GO:0097105 50057 XM_029349865.2 125 0 0 118 48 P50211 1.85e-123 Insulin gene enhancer protein ISL-1 (Islet-1) Gallus gallus (Chicken) atrial septum morphogenesis [GO:0060413]; axonogenesis [GO:0007409]; canonical Wnt signaling pathway [GO:0060070]; cardiac cell fate determination [GO:0060913]; cardiac muscle cell myoblast differentiation [GO:0060379]; cardiac right ventricle morphogenesis [GO:0003215]; cell population proliferation [GO:0008283]; endocardial cushion morphogenesis [GO:0003203]; heart development [GO:0007507]; innervation [GO:0060384]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural crest cell migration [GO:0001755]; neuron fate specification [GO:0048665]; outflow tract septum morphogenesis [GO:0003148]; pancreas development [GO:0031016]; peripheral nervous system neuron axonogenesis [GO:0048936]; pharyngeal system development [GO:0060037]; pituitary gland development [GO:0021983]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA binding [GO:0043388]; positive regulation of granulocyte colony-stimulating factor production [GO:0071657]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of histone acetylation [GO:0035066]; positive regulation of insulin secretion [GO:0032024]; positive regulation of interleukin-1 alpha production [GO:0032730]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type II interferon production [GO:0032729]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of secondary heart field cardioblast proliferation [GO:0003266]; regulation of transcription by RNA polymerase II [GO:0006357]; retinal ganglion cell axon guidance [GO:0031290]; secondary heart field specification [GO:0003139]; sensory system development [GO:0048880]; sinoatrial node cell development [GO:0060931]; spinal cord motor neuron cell fate specification [GO:0021520]; transcription by RNA polymerase II [GO:0006366]; trigeminal nerve development [GO:0021559]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; visceral motor neuron differentiation [GO:0021524] GO:0000122; GO:0000785; GO:0000978; GO:0000981; GO:0000987; GO:0001228; GO:0001755; GO:0003139; GO:0003148; GO:0003203; GO:0003215; GO:0003266; GO:0005634; GO:0006357; GO:0006366; GO:0007409; GO:0007507; GO:0008283; GO:0008284; GO:0010575; GO:0021520; GO:0021524; GO:0021559; GO:0021983; GO:0031016; GO:0031290; GO:0032024; GO:0032725; GO:0032729; GO:0032730; GO:0032731; GO:0032735; GO:0032755; GO:0032760; GO:0035066; GO:0042531; GO:0043388; GO:0043425; GO:0043524; GO:0045597; GO:0045665; GO:0045766; GO:0045892; GO:0045944; GO:0046872; GO:0048665; GO:0048880; GO:0048936; GO:0050728; GO:0055010; GO:0060037; GO:0060070; GO:0060379; GO:0060384; GO:0060413; GO:0060913; GO:0060931; GO:0061629; GO:0071657; GO:0086091; GO:0090090; GO:1990841 50058 XM_044317744.1 38 21 10 22 26 Q9I928 4.97e-21 Fucolectin-4 Anguilla japonica (Japanese eel) regulation of cellular defense response [GO:0010185]; regulation of complement activation, lectin pathway [GO:0001868]; regulation of innate immune response [GO:0045088] GO:0001868; GO:0005509; GO:0005615; GO:0010185; GO:0030246; GO:0042806; GO:0045088 50059 XM_044317234.1 0 14 17 9 15 NA NA NA NA NA NA 50060 XM_044327901.1 94 46 155 67 123 NA NA NA NA NA NA 50061 XM_029348772.2 228 437 52 0 0 Q5RDN9 6.89e-73 Protein yippee-like 2 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0005730; GO:0046872 50062 XM_044326031.1 5445 3927 3184 4716 5032 Q4H4B6 9.62e-155 Protein scribble homolog (Scribble1) Danio rerio (Zebrafish) (Brachydanio rerio) activation of GTPase activity [GO:0090630]; anterior/posterior axon guidance [GO:0033564]; apoptotic process involved in morphogenesis [GO:0060561]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cell-cell adhesion [GO:0098609]; commissural neuron axon guidance [GO:0071679]; convergent extension involved in gastrulation [GO:0060027]; establishment of apical/basal cell polarity [GO:0035089]; establishment of mitotic spindle orientation [GO:0000132]; establishment of planar polarity [GO:0001736]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; motor neuron migration [GO:0097475]; negative regulation of mitotic cell cycle [GO:0045930]; neural tube formation [GO:0001841]; neuromast development [GO:0048884]; neuron migration [GO:0001764]; neurotransmitter receptor transport postsynaptic membrane to endosome [GO:0098968]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; positive chemotaxis [GO:0050918]; positive regulation of apoptotic process [GO:0043065]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; vasculature development [GO:0001944] GO:0000132; GO:0001736; GO:0001764; GO:0001841; GO:0001944; GO:0005737; GO:0005886; GO:0005911; GO:0005912; GO:0008283; GO:0014069; GO:0016020; GO:0016323; GO:0016477; GO:0030027; GO:0030054; GO:0033564; GO:0035089; GO:0043065; GO:0043113; GO:0045197; GO:0045930; GO:0046982; GO:0048884; GO:0050918; GO:0060027; GO:0060561; GO:0071679; GO:0090630; GO:0097120; GO:0097475; GO:0098609; GO:0098793; GO:0098887; GO:0098968 50063 XM_044326031.1 5445 3927 3184 4716 5032 Q4H4B6 2.76e-129 Protein scribble homolog (Scribble1) Danio rerio (Zebrafish) (Brachydanio rerio) activation of GTPase activity [GO:0090630]; anterior/posterior axon guidance [GO:0033564]; apoptotic process involved in morphogenesis [GO:0060561]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cell-cell adhesion [GO:0098609]; commissural neuron axon guidance [GO:0071679]; convergent extension involved in gastrulation [GO:0060027]; establishment of apical/basal cell polarity [GO:0035089]; establishment of mitotic spindle orientation [GO:0000132]; establishment of planar polarity [GO:0001736]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; motor neuron migration [GO:0097475]; negative regulation of mitotic cell cycle [GO:0045930]; neural tube formation [GO:0001841]; neuromast development [GO:0048884]; neuron migration [GO:0001764]; neurotransmitter receptor transport postsynaptic membrane to endosome [GO:0098968]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; positive chemotaxis [GO:0050918]; positive regulation of apoptotic process [GO:0043065]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; vasculature development [GO:0001944] GO:0000132; GO:0001736; GO:0001764; GO:0001841; GO:0001944; GO:0005737; GO:0005886; GO:0005911; GO:0005912; GO:0008283; GO:0014069; GO:0016020; GO:0016323; GO:0016477; GO:0030027; GO:0030054; GO:0033564; GO:0035089; GO:0043065; GO:0043113; GO:0045197; GO:0045930; GO:0046982; GO:0048884; GO:0050918; GO:0060027; GO:0060561; GO:0071679; GO:0090630; GO:0097120; GO:0097475; GO:0098609; GO:0098793; GO:0098887; GO:0098968 50064 XR_006391578.1 1 12 0 10 8 NA NA NA NA NA NA 50065 XM_044317638.1 0 0 46 0 467 NA NA NA NA NA NA 50066 XM_044310473.1 907 255 449 454 137 NA NA NA NA NA NA 50067 XM_029332871.2 13599 14111 8698 19457 18183 B8VIX3 0 Uncharacterized skeletal organic matrix protein 6 (Uncharacterized SOMP-6) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 50068 XM_044309043.1 456 643 343 460 424 NA NA NA NA NA NA 50069 XR_003828306.2 0 47 0 5 18 Q86AW9 4.07e-116 Guanine deaminase (Guanase) (Guanine aminase) (EC 3.5.4.3) (Guanine aminohydrolase) (GAH) Dictyostelium discoideum (Social amoeba) guanine catabolic process [GO:0006147]; guanine metabolic process [GO:0046098] GO:0005829; GO:0006147; GO:0008270; GO:0008892; GO:0019239; GO:0046098 50070 XM_029349584.2 416 351 271 205 196 Q7ZVB2 0 4-trimethylaminobutyraldehyde dehydrogenase A (TMABA-DH) (TMABADH) (EC 1.2.1.47) (Aldehyde dehydrogenase family 9 member A1-A) (EC 1.2.1.3) Danio rerio (Zebrafish) (Brachydanio rerio) carnitine biosynthetic process [GO:0045329]; cellular aldehyde metabolic process [GO:0006081]; protein homotetramerization [GO:0051289] GO:0004029; GO:0005829; GO:0006081; GO:0019145; GO:0043878; GO:0045329; GO:0047105; GO:0051289 50071 XM_029346389.2 3 0 14 0 1 NA NA NA NA NA NA 50072 XM_029324471.2 597 329 381 705 655 O75376 1.02e-80 Nuclear receptor corepressor 1 (N-CoR) (N-CoR1) Homo sapiens (Human) chromatin organization [GO:0006325]; locomotor rhythm [GO:0045475]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of fatty acid metabolic process [GO:0045922]; negative regulation of glycolytic process [GO:0045820]; negative regulation of JNK cascade [GO:0046329]; negative regulation of miRNA transcription [GO:1902894]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357]; spindle assembly [GO:0051225] GO:0000118; GO:0000122; GO:0000785; GO:0000976; GO:0003714; GO:0005634; GO:0005654; GO:0005829; GO:0006325; GO:0006357; GO:0016020; GO:0016922; GO:0017053; GO:0042826; GO:0045475; GO:0045820; GO:0045892; GO:0045922; GO:0046329; GO:0046966; GO:0051225; GO:0060766; GO:0061629; GO:0072686; GO:1902894 50073 XM_029351727.2 0 0 8 13 1 NA NA NA NA NA NA 50074 XM_044328003.1 52 81 173 89 143 NA NA NA NA NA NA 50075 XM_044328695.1 0 39 20 41 1 O09118 0 Netrin-1 Mus musculus (Mouse) animal organ morphogenesis [GO:0009887]; anterior/posterior axon guidance [GO:0033564]; apoptotic process [GO:0006915]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; B cell mediated immunity [GO:0019724]; B cell proliferation [GO:0042100]; Cdc42 protein signal transduction [GO:0032488]; cell population proliferation [GO:0008283]; cell-cell adhesion [GO:0098609]; chemorepulsion of axon [GO:0061643]; dendrite development [GO:0016358]; glial cell proliferation [GO:0014009]; inner ear morphogenesis [GO:0042472]; mammary gland development [GO:0030879]; mammary gland duct morphogenesis [GO:0060603]; motor neuron axon guidance [GO:0008045]; motor neuron migration [GO:0097475]; negative regulation of axon extension [GO:0030517]; neuron migration [GO:0001764]; nuclear migration [GO:0007097]; positive regulation of axon extension [GO:0045773]; positive regulation of cell motility [GO:2000147]; positive regulation of glial cell proliferation [GO:0060252]; Ras protein signal transduction [GO:0007265]; regulation of cell migration [GO:0030334]; regulation of glial cell migration [GO:1903975]; regulation of synapse assembly [GO:0051963]; substrate-dependent cell migration, cell extension [GO:0006930]; T cell mediated immunity [GO:0002456]; tissue development [GO:0009888] GO:0001764; GO:0002456; GO:0005125; GO:0005576; GO:0005604; GO:0005654; GO:0005737; GO:0005829; GO:0006915; GO:0006930; GO:0007097; GO:0007265; GO:0007409; GO:0007411; GO:0008045; GO:0008283; GO:0009887; GO:0009888; GO:0014009; GO:0015629; GO:0016358; GO:0019724; GO:0030334; GO:0030517; GO:0030879; GO:0031012; GO:0032488; GO:0033564; GO:0042100; GO:0042472; GO:0045773; GO:0051963; GO:0060252; GO:0060603; GO:0061643; GO:0062023; GO:0071944; GO:0097475; GO:0098609; GO:1903975; GO:2000147 50076 XM_044315755.1 2 0 22 17 22 NA NA NA NA NA NA 50077 XM_029357469.2 61 22 0 0 0 NA NA NA NA NA NA 50078 XM_044312610.1 24 8 18 24 15 NA NA NA NA NA NA 50079 XM_044323935.1 64 23 26 80 11 Q5R9I3 1.23e-27 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cellular response to glucose starvation [GO:0042149]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; protein phosphorylation [GO:0006468] GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005930; GO:0006468; GO:0016236; GO:0035032; GO:0042149; GO:0045324; GO:0106310 50080 XM_044321354.1 73 0 0 0 0 Q96PY6 1.01e-145 Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase 1) (NimA-related protein kinase 1) (Renal carcinoma antigen NY-REN-55) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; cilium assembly [GO:0060271]; protein phosphorylation [GO:0006468] GO:0000242; GO:0004672; GO:0004674; GO:0004713; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0005829; GO:0006468; GO:0007049; GO:0016301; GO:0034451; GO:0046872; GO:0051301; GO:0060271; GO:0071889; GO:0106310 50081 XM_029325023.2 1041 633 470 938 992 Q99JY4 5.12e-101 TraB domain-containing protein Mus musculus (Mouse) NA NA 50082 XM_044316342.1 49 25 18 48 51 Q96AY4 1.53e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 50083 XM_044316342.1 49 25 18 48 51 Q96AY4 4.36e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 50084 XM_044316342.1 49 25 18 48 51 Q96AY4 1.73e-55 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 50085 XM_044316342.1 49 25 18 48 51 Q96AY4 2.01e-54 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 50086 XM_044316342.1 49 25 18 48 51 Q96AY4 1.94e-49 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 50087 XM_044316342.1 49 25 18 48 51 Q96AY4 1.49e-46 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 50088 XM_044316342.1 49 25 18 48 51 Q96AY4 1.22e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 50089 XM_044316342.1 49 25 18 48 51 Q96AY4 4.99e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 50090 XM_044310438.1 0 0 9 0 40 NA NA NA NA NA NA 50091 XM_029357069.2 1557 1326 1112 1286 1502 Q61586 1.92e-120 Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAT-1) (EC 2.3.1.15) (P90) Mus musculus (Mouse) activated T cell proliferation [GO:0050798]; activation-induced cell death of T cells [GO:0006924]; acyl-CoA metabolic process [GO:0006637]; CDP-diacylglycerol biosynthetic process [GO:0016024]; cellular response to insulin stimulus [GO:0032869]; defense response to virus [GO:0051607]; diacylglycerol biosynthetic process [GO:0006651]; fatty acid homeostasis [GO:0055089]; fatty acid metabolic process [GO:0006631]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerophospholipid metabolic process [GO:0006650]; negative regulation of activation-induced cell death of T cells [GO:0070236]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidylglycerol biosynthetic process [GO:0006655]; phospholipid biosynthetic process [GO:0008654]; phospholipid homeostasis [GO:0055091]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of triglyceride biosynthetic process [GO:0010867]; regulation of cytokine production [GO:0001817]; response to activity [GO:0014823]; response to glucose [GO:0009749]; triglyceride biosynthetic process [GO:0019432]; triglyceride metabolic process [GO:0006641] GO:0001817; GO:0004366; GO:0005739; GO:0005741; GO:0005743; GO:0005886; GO:0006072; GO:0006631; GO:0006637; GO:0006641; GO:0006650; GO:0006651; GO:0006654; GO:0006655; GO:0006924; GO:0008654; GO:0009749; GO:0010867; GO:0014823; GO:0016024; GO:0019432; GO:0031966; GO:0032869; GO:0040018; GO:0042104; GO:0050798; GO:0051607; GO:0055089; GO:0055091; GO:0070236; GO:0102420 50092 XM_044326995.1 3 7 2 26 7 B8VIW9 7.8e-111 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 50093 XM_029340206.2 280 232 177 362 237 B0G143 1.45e-69 Mitochondrial substrate carrier family protein ucpB (Solute carrier family 25 member 30 homolog) (Uncoupler protein B) Dictyostelium discoideum (Social amoeba) mitochondrial transport [GO:0006839] GO:0005743; GO:0006839; GO:0022857 50094 XM_044309135.1 110 57 151 194 181 NA NA NA NA NA NA 50095 XM_029334175.2 401 266 15 45 402 NA NA NA NA NA NA 50096 XM_029348964.2 236 190 274 414 230 NA NA NA NA NA NA 50097 XM_029344229.2 958 545 463 819 737 Q02410 5.65e-134 Amyloid-beta A4 precursor protein-binding family A member 1 (Adapter protein X11alpha) (Neuron-specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint-1) Homo sapiens (Human) axo-dendritic transport [GO:0008088]; cell adhesion [GO:0007155]; chemical synaptic transmission [GO:0007268]; gamma-aminobutyric acid secretion [GO:0014051]; glutamate secretion [GO:0014047]; in utero embryonic development [GO:0001701]; intracellular protein transport [GO:0006886]; locomotory behavior [GO:0007626]; multicellular organism growth [GO:0035264]; nervous system development [GO:0007399]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; protein-containing complex assembly [GO:0065003]; regulation of gene expression [GO:0010468] GO:0001540; GO:0001701; GO:0005634; GO:0005737; GO:0005794; GO:0005829; GO:0005886; GO:0006886; GO:0007155; GO:0007268; GO:0007399; GO:0007626; GO:0008021; GO:0008088; GO:0010468; GO:0014047; GO:0014051; GO:0035264; GO:0043197; GO:0048471; GO:0048787; GO:0065003; GO:0098685; GO:0098978; GO:0099171 50098 XM_044322707.1 20 73 10 17 44 Q9BRD0 1.8e-29 BUD13 homolog Homo sapiens (Human) mRNA splicing, via spliceosome [GO:0000398]; U2-type prespliceosome assembly [GO:1903241] GO:0000398; GO:0003723; GO:0005634; GO:0005654; GO:0005681; GO:0005684; GO:0005686; GO:0070274; GO:0071005; GO:1903241 50099 XM_029354482.2 111 121 162 52 161 NA NA NA NA NA NA 50100 XM_044324451.1 0 34 0 0 0 NA NA NA NA NA NA 50101 XR_003826280.2 11 30 18 45 38 NA NA NA NA NA NA 50102 XM_029339952.2 207 158 221 202 296 NA NA NA NA NA NA 50103 XM_029349860.2 1664 1637 672 1250 846 Q6NLT8 3.43e-32 NA NA NA NA 50104 XR_003825663.2 0 0 0 5 14 NA NA NA NA NA NA 50105 XM_029343987.2 0 12 16 64 80 Q9D1D1 1.18e-39 Tetraspanin-11 (Tspan-11) Mus musculus (Mouse) cell migration [GO:0016477] GO:0005886; GO:0016477 50106 XM_029331847.2 215 17 146 145 33 Q5RJA1 0 DNA-binding protein RFX6 (Regulatory factor X 6) Danio rerio (Zebrafish) (Brachydanio rerio) endocrine pancreas development [GO:0031018]; glucose homeostasis [GO:0042593]; pancreatic A cell differentiation [GO:0003310]; pancreatic D cell differentiation [GO:0003311]; pancreatic epsilon cell differentiation [GO:0090104]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of insulin secretion [GO:0050796]; regulation of transcription by RNA polymerase II [GO:0006357]; type B pancreatic cell differentiation [GO:0003309] GO:0000976; GO:0000978; GO:0000981; GO:0003309; GO:0003310; GO:0003311; GO:0005634; GO:0006357; GO:0031018; GO:0035774; GO:0042593; GO:0045893; GO:0045944; GO:0050796; GO:0090104 50107 XM_044317915.1 150 182 49 127 44 O55230 2.97e-68 DNA repair protein RAD51 homolog 4 (R51H3) (RAD51 homolog D) (RAD51-like protein 3) Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; chromosome organization [GO:0051276]; double-strand break repair via homologous recombination [GO:0000724]; interstrand cross-link repair [GO:0036297]; reciprocal meiotic recombination [GO:0007131]; regulation of cell cycle [GO:0051726]; strand invasion [GO:0042148]; telomere maintenance [GO:0000723]; telomere maintenance via recombination [GO:0000722] GO:0000400; GO:0000722; GO:0000723; GO:0000724; GO:0000781; GO:0003697; GO:0005524; GO:0005657; GO:0005813; GO:0006974; GO:0007131; GO:0008094; GO:0033063; GO:0036297; GO:0042148; GO:0043015; GO:0051276; GO:0051726; GO:0140664 50108 XM_029337827.2 176 70 91 305 159 O75762 6.89e-102 Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation-sensitive protein p120) (p120) (Wasabi receptor) Homo sapiens (Human) calcium ion transmembrane transport [GO:0070588]; cell surface receptor signaling pathway [GO:0007166]; cellular calcium ion homeostasis [GO:0006874]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to organic substance [GO:0071310]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; ion transport [GO:0006811]; protein homotetramerization [GO:0051289]; response to cold [GO:0009409]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; sensory perception of pain [GO:0019233]; thermoception [GO:0050955] GO:0005262; GO:0005886; GO:0006811; GO:0006874; GO:0007166; GO:0009409; GO:0009410; GO:0010033; GO:0014070; GO:0015267; GO:0015278; GO:0019233; GO:0032421; GO:0042802; GO:0048265; GO:0050955; GO:0050966; GO:0050968; GO:0051289; GO:0070301; GO:0070588; GO:0071310; GO:0097604 50109 XR_006391613.1 974 1575 833 1054 1112 NA NA NA NA NA NA 50110 XM_044311696.1 158 50 155 135 1 Q96T58 8.51e-62 Msx2-interacting protein (SMART/HDAC1-associated repressor protein) (SPEN homolog) Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of neurogenesis [GO:0050769]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0003677; GO:0003714; GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0006357; GO:0007219; GO:0017053; GO:0045892; GO:0050769; GO:0061629; GO:0070062 50111 XM_044311696.1 158 50 155 135 1 Q96T58 6.43e-59 Msx2-interacting protein (SMART/HDAC1-associated repressor protein) (SPEN homolog) Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of neurogenesis [GO:0050769]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0003677; GO:0003714; GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0006357; GO:0007219; GO:0017053; GO:0045892; GO:0050769; GO:0061629; GO:0070062 50112 XM_029350486.2 249 166 168 260 248 NA NA NA NA NA NA 50113 XM_029344855.2 25 19 48 13 81 Q6DIV6 3.2e-55 Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Solute carrier family 32 member 1) (Vesicular GABA transporter) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) beta-alanine transport [GO:0001762]; gamma-aminobutyric acid import [GO:0051939]; gamma-aminobutyric acid transport [GO:0015812]; glycine transport [GO:0015816]; neurotransmitter transport [GO:0006836] GO:0001762; GO:0006836; GO:0008021; GO:0015185; GO:0015187; GO:0015812; GO:0015816; GO:0030659; GO:0042995; GO:0051939; GO:0098793; GO:0140799; GO:0140800 50114 XR_006397099.1 5 0 4 2 8 NA NA NA NA NA NA 50115 XM_029347236.2 167 115 128 167 142 NA NA NA NA NA NA 50116 XM_044312668.1 4 9 18 0 53 NA NA NA NA NA NA 50117 XM_029336623.2 3937 4125 3314 3580 3794 NA NA NA NA NA NA 50118 XM_029336449.2 36 0 12 8 0 Q6ZNB5 5.51e-28 Protein XNDC1N (XRCC1 N-terminal domain-containing 1 N-terminal like) Homo sapiens (Human) single strand break repair [GO:0000012] GO:0000012; GO:0003684; GO:0005694; GO:0005730 50119 XM_044322905.1 171 68 23 192 147 Q5ZL23 2.56e-66 Amyloid beta A4 precursor protein-binding family B member 1-interacting protein (APBB1-interacting protein 1) Gallus gallus (Chicken) signal transduction [GO:0007165] GO:0005829; GO:0005856; GO:0005886; GO:0007165 50120 XM_029350490.2 271 262 171 141 173 NA NA NA NA NA NA 50121 XM_029334466.2 407 0 441 317 470 Q6DKN2 9.6e-32 Homeobox protein OTX2-B (xOTX2-B) (Orthodenticle 2-B) (Orthodenticle-A-like protein B) Xenopus laevis (African clawed frog) NA GO:0000981; GO:0003677; GO:0005634 50122 XM_029358754.2 0 0 0 234 94 Q8BTM8 6.89e-32 Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin) Mus musculus (Mouse) actin crosslink formation [GO:0051764]; actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; angiogenesis [GO:0001525]; blood coagulation, intrinsic pathway [GO:0007597]; blood vessel remodeling [GO:0001974]; cell-cell junction organization [GO:0045216]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; early endosome to late endosome transport [GO:0045022]; epithelial to mesenchymal transition [GO:0001837]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; heart morphogenesis [GO:0003007]; megakaryocyte development [GO:0035855]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of axon regeneration [GO:0048680]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of platelet activation [GO:0010572]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; release of sequestered calcium ion into cytosol [GO:0051209]; semaphorin-plexin signaling pathway [GO:0071526]; synapse organization [GO:0050808]; tubulin deacetylation [GO:0090042]; wound healing, spreading of cells [GO:0044319] GO:0001525; GO:0001664; GO:0001837; GO:0001974; GO:0003007; GO:0003779; GO:0005080; GO:0005634; GO:0005730; GO:0005737; GO:0005802; GO:0005829; GO:0005884; GO:0005886; GO:0005903; GO:0005911; GO:0005938; GO:0007195; GO:0007597; GO:0010572; GO:0010977; GO:0015459; GO:0015629; GO:0016479; GO:0019900; GO:0021943; GO:0030018; GO:0030036; GO:0030334; GO:0030426; GO:0030863; GO:0031267; GO:0031523; GO:0031532; GO:0031852; GO:0032231; GO:0032233; GO:0032432; GO:0034394; GO:0034988; GO:0035855; GO:0042177; GO:0042307; GO:0042789; GO:0042803; GO:0043025; GO:0043066; GO:0043113; GO:0043123; GO:0043198; GO:0043204; GO:0043433; GO:0044295; GO:0044319; GO:0044325; GO:0044877; GO:0045022; GO:0045184; GO:0045216; GO:0046332; GO:0048471; GO:0048680; GO:0050808; GO:0050821; GO:0051015; GO:0051020; GO:0051209; GO:0051220; GO:0051764; GO:0060271; GO:0071526; GO:0072659; GO:0090042; GO:0090307; GO:0097368; GO:0097440; GO:0098794; GO:0098978; GO:0140297; GO:1900026; GO:1901381; GO:1902396; GO:1905000; GO:1905031; GO:1990779; GO:2000179; GO:2001046; GO:2001224 50123 XM_044310744.1 12 0 0 0 49 NA NA NA NA NA NA 50124 XR_006395034.1 3 3 3 3 14 NA NA NA NA NA NA 50125 XM_029345915.2 939 711 628 1570 1174 P23359 3.68e-86 Bone morphogenetic protein 7 (BMP-7) (Osteogenic protein 1) (OP-1) Mus musculus (Mouse) allantois development [GO:1905069]; ameloblast differentiation [GO:0036305]; anatomical structure formation involved in morphogenesis [GO:0048646]; animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; BMP signaling pathway [GO:0030509]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle tissue development [GO:0048738]; cardiac septum morphogenesis [GO:0060411]; cartilage development [GO:0051216]; cell development [GO:0048468]; cell population proliferation [GO:0008283]; cellular response to BMP stimulus [GO:0071773]; chorio-allantoic fusion [GO:0060710]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic skeletal joint morphogenesis [GO:0060272]; endocardial cushion formation [GO:0003272]; epithelial cell differentiation [GO:0030855]; eye development [GO:0001654]; heart trabecula morphogenesis [GO:0061384]; hindbrain development [GO:0030902]; kidney development [GO:0001822]; mesenchymal cell apoptotic process involved in nephron morphogenesis [GO:1901145]; mesenchymal cell differentiation [GO:0048762]; mesenchyme development [GO:0060485]; mesoderm formation [GO:0001707]; metanephric mesenchymal cell proliferation involved in metanephros development [GO:0072136]; metanephric mesenchyme morphogenesis [GO:0072133]; monocyte aggregation [GO:0070487]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell death [GO:0060548]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of glomerular mesangial cell proliferation [GO:0072125]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis [GO:0072040]; negative regulation of mitotic nuclear division [GO:0045839]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of phosphorylation [GO:0042326]; negative regulation of prostatic bud formation [GO:0060686]; nephrogenic mesenchyme morphogenesis [GO:0072134]; neural fold elevation formation [GO:0021502]; neuron projection morphogenesis [GO:0048812]; odontogenesis of dentin-containing tooth [GO:0042475]; ossification [GO:0001503]; pattern specification process [GO:0007389]; pericardium morphogenesis [GO:0003344]; pharyngeal system development [GO:0060037]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone mineralization [GO:0030501]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis [GO:1905312]; positive regulation of cell death [GO:0010942]; positive regulation of dendrite development [GO:1900006]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial cell differentiation [GO:0030858]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of gene expression [GO:0010628]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of hyaluranon cable assembly [GO:1900106]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to nucleus [GO:0034504]; regulation of branching involved in prostate gland morphogenesis [GO:0060687]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of phosphorylation [GO:0042325]; response to estradiol [GO:0032355]; response to peptide hormone [GO:0043434]; response to vitamin D [GO:0033280]; salivary gland morphogenesis [GO:0007435]; SMAD protein signal transduction [GO:0060395]; steroid hormone mediated signaling pathway [GO:0043401]; tube morphogenesis [GO:0035239]; ureteric bud development [GO:0001657] GO:0001503; GO:0001654; GO:0001657; GO:0001707; GO:0001822; GO:0003272; GO:0003344; GO:0005125; GO:0005615; GO:0007389; GO:0007411; GO:0007435; GO:0008083; GO:0008201; GO:0008283; GO:0008285; GO:0009880; GO:0009887; GO:0010628; GO:0010718; GO:0010800; GO:0010862; GO:0010942; GO:0021502; GO:0030326; GO:0030501; GO:0030509; GO:0030855; GO:0030858; GO:0030902; GO:0031982; GO:0032355; GO:0033280; GO:0034116; GO:0034504; GO:0035239; GO:0036305; GO:0042325; GO:0042326; GO:0042475; GO:0043065; GO:0043401; GO:0043407; GO:0043434; GO:0045665; GO:0045666; GO:0045669; GO:0045746; GO:0045786; GO:0045839; GO:0045892; GO:0045893; GO:0045944; GO:0048468; GO:0048593; GO:0048596; GO:0048646; GO:0048738; GO:0048754; GO:0048762; GO:0048812; GO:0050768; GO:0051216; GO:0060037; GO:0060272; GO:0060391; GO:0060393; GO:0060395; GO:0060411; GO:0060445; GO:0060485; GO:0060548; GO:0060686; GO:0060687; GO:0060710; GO:0061384; GO:0062023; GO:0070487; GO:0070700; GO:0071773; GO:0072040; GO:0072125; GO:0072133; GO:0072134; GO:0072136; GO:0090336; GO:1900006; GO:1900106; GO:1901145; GO:1905069; GO:1905312 50126 XM_044326309.1 2 0 63 0 0 Q9DC53 0 Copine-8 (Copine VIII) Mus musculus (Mouse) cellular response to calcium ion [GO:0071277] GO:0005544; GO:0005886; GO:0046872; GO:0071277 50127 XM_044325281.1 6 0 0 0 5 NA NA NA NA NA NA 50128 XM_029345467.2 62 17 0 0 6 Q8N2E2 1.52e-39 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 50129 XM_029345467.2 62 17 0 0 6 Q8N2E2 9.2e-38 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 50130 XM_029345467.2 62 17 0 0 6 Q8N2E2 1.63e-36 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 50131 XM_029345467.2 62 17 0 0 6 Q8N2E2 5.12e-35 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 50132 XM_029345467.2 62 17 0 0 6 Q8N2E2 6.02e-32 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 50133 XM_029345467.2 62 17 0 0 6 Q8N2E2 4.41e-25 von Willebrand factor D and EGF domain-containing protein Homo sapiens (Human) anatomical structure development [GO:0048856] GO:0005102; GO:0005576; GO:0009986; GO:0048856 50134 XM_044311663.1 63 30 46 93 74 NA NA NA NA NA NA 50135 XM_029352015.2 2104 2048 707 1668 1646 Q9W719 2.91e-94 Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (HGPRTase) (EC 2.4.2.8) Gallus gallus (Chicken) GMP catabolic process [GO:0046038]; GMP salvage [GO:0032263]; guanine salvage [GO:0006178]; hypoxanthine metabolic process [GO:0046100]; hypoxanthine salvage [GO:0043103]; IMP metabolic process [GO:0046040]; IMP salvage [GO:0032264]; positive regulation of dopamine metabolic process [GO:0045964]; purine nucleotide biosynthetic process [GO:0006164]; purine ribonucleoside salvage [GO:0006166] GO:0000166; GO:0000287; GO:0002057; GO:0002060; GO:0004422; GO:0005694; GO:0005737; GO:0005829; GO:0006164; GO:0006166; GO:0006178; GO:0032263; GO:0032264; GO:0042802; GO:0043103; GO:0045964; GO:0046038; GO:0046040; GO:0046100; GO:0052657 50136 XM_029328675.2 6 64 49 52 142 Q640I9 3.13e-109 Lysine-specific demethylase 2B (EC 1.14.11.27) (F-box and leucine-rich repeat protein 10) (F-box/LRR-repeat protein 10) (JmjC domain-containing histone demethylation protein 1B) ([Histone-H3]-lysine-36 demethylase 1B) Xenopus laevis (African clawed frog) chromatin organization [GO:0006325]; histone H3-K36 demethylation [GO:0070544] GO:0005634; GO:0005694; GO:0005730; GO:0006325; GO:0008270; GO:0019843; GO:0045322; GO:0051864; GO:0070544; GO:0140680 50137 XM_029328675.2 6 64 49 52 142 Q640I9 6.58e-61 Lysine-specific demethylase 2B (EC 1.14.11.27) (F-box and leucine-rich repeat protein 10) (F-box/LRR-repeat protein 10) (JmjC domain-containing histone demethylation protein 1B) ([Histone-H3]-lysine-36 demethylase 1B) Xenopus laevis (African clawed frog) chromatin organization [GO:0006325]; histone H3-K36 demethylation [GO:0070544] GO:0005634; GO:0005694; GO:0005730; GO:0006325; GO:0008270; GO:0019843; GO:0045322; GO:0051864; GO:0070544; GO:0140680 50138 XM_044308264.1 0 4 7 17 0 P48380 0 Transcription factor RFX3 (Regulatory factor X 3) Homo sapiens (Human) cell maturation [GO:0048469]; cilium assembly [GO:0060271]; cilium-dependent cell motility [GO:0060285]; endocrine pancreas development [GO:0031018]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type B pancreatic cell development [GO:2000078]; regulation of DNA-templated transcription [GO:0006355]; regulation of insulin secretion [GO:0050796]; regulation of transcription by RNA polymerase II [GO:0006357]; type B pancreatic cell maturation [GO:0072560] GO:0000785; GO:0000976; GO:0000978; GO:0000981; GO:0003677; GO:0003700; GO:0005576; GO:0005634; GO:0005667; GO:0006355; GO:0006357; GO:0031018; GO:0045892; GO:0045893; GO:0045944; GO:0048469; GO:0050796; GO:0060271; GO:0060285; GO:0060287; GO:0072560; GO:1990837; GO:2000078 50139 XR_006393635.1 261 350 146 62 244 NA NA NA NA NA NA 50140 XR_006397119.1 0 12 5 1 0 NA NA NA NA NA NA 50141 XM_044325687.1 106 28 43 134 72 Q8IUL8 3.58e-78 Cartilage intermediate layer protein 2 (CILP-2) [Cleaved into: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2] Homo sapiens (Human) NA GO:0005615; GO:0070062 50142 XM_029331245.2 125 387 348 183 444 O54916 1.28e-25 RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1) Mus musculus (Mouse) endocytosis [GO:0006897]; endosomal transport [GO:0016197] GO:0005509; GO:0005886; GO:0005905; GO:0006897; GO:0016197; GO:0017124 50143 XM_029328850.2 1813 1139 1502 1747 2528 B1AY13 0 Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.4.19.12) (Deubiquitinating enzyme 24) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24) Mus musculus (Mouse) protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004197; GO:0004843; GO:0005634; GO:0005829; GO:0006511; GO:0016579 50144 XM_029343134.2 431 364 263 375 685 Q9VCP0 2.41e-37 Transcription elongation factor B polypeptide 3 (Elongin-A) (RNA polymerase II transcription factor SIII subunit A) (dEloA) Drosophila melanogaster (Fruit fly) imaginal disc-derived wing vein specification [GO:0007474]; transcription elongation by RNA polymerase II promoter [GO:0006368] GO:0005634; GO:0006368; GO:0007474; GO:0008023; GO:0070449 50145 XR_006396013.1 9 0 0 0 12 NA NA NA NA NA NA 50146 XR_003824550.2 17 0 10 20 20 NA NA NA NA NA NA 50147 XM_029339466.2 12711 10735 7025 18160 13770 B3EWZ3 0 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 50148 XM_029333524.2 6213 6268 4045 5045 5129 Q68EK7 7.03e-117 Ras-related protein Rab-4B (EC 3.6.5.2) Danio rerio (Zebrafish) (Brachydanio rerio) protein transport [GO:0015031]; Rab protein signal transduction [GO:0032482]; regulation of endocytosis [GO:0030100]; vesicle-mediated transport [GO:0016192] GO:0003924; GO:0003925; GO:0005525; GO:0005768; GO:0005886; GO:0015031; GO:0016192; GO:0030100; GO:0032482; GO:0032593; GO:0055037 50149 XM_029329828.2 0 25 39 82 32 NA NA NA NA NA NA 50150 XM_029334212.2 130 70 98 189 462 NA NA NA NA NA NA 50151 XM_029334219.2 0 0 0 13 0 Q6DIL6 5.14e-29 Protein FAM124A Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA NA 50152 XR_006394825.1 111 136 141 275 240 NA NA NA NA NA NA 50153 XM_029339261.2 16 0 0 0 4 Q9N2B7 3.43e-39 5-hydroxytryptamine receptor 1B (5-HT-1B) (5-HT1B) (Serotonin receptor 1B) Gorilla gorilla gorilla (Western lowland gorilla) adenylate cyclase-inhibiting serotonin receptor signaling pathway [GO:0007198]; behavior [GO:0007610]; bone remodeling [GO:0046849]; cellular response to alkaloid [GO:0071312]; cellular response to xenobiotic stimulus [GO:0071466]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; negative regulation of serotonin secretion [GO:0014063]; regulation of behavior [GO:0050795]; vasoconstriction [GO:0042310] GO:0004993; GO:0005886; GO:0007187; GO:0007198; GO:0007268; GO:0007610; GO:0014063; GO:0030425; GO:0030594; GO:0042310; GO:0045202; GO:0046849; GO:0050795; GO:0051378; GO:0071312; GO:0071466 50154 XM_029343446.2 53 0 0 34 53 NA NA NA NA NA NA 50155 XR_006394671.1 353 178 291 92 1224 NA NA NA NA NA NA 50156 XM_044312169.1 15 27 79 37 132 NA NA NA NA NA NA 50157 XR_006393181.1 330 412 747 247 1047 NA NA NA NA NA NA 50158 XM_029353487.2 15 13 13 6 72 NA NA NA NA NA NA 50159 XM_044326030.1 155 118 113 58 77 P34147 4.4e-44 Rho-related protein racA Dictyostelium discoideum (Social amoeba) actin filament organization [GO:0007015]; cortical cytoskeleton organization [GO:0030865]; establishment or maintenance of cell polarity [GO:0007163]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; response to bacterium [GO:0009617]; small GTPase mediated signal transduction [GO:0007264] GO:0003924; GO:0005525; GO:0005856; GO:0005886; GO:0005938; GO:0007015; GO:0007163; GO:0007264; GO:0008360; GO:0009617; GO:0019901; GO:0030865; GO:0031410; GO:0032956; GO:0042995 50160 XM_029343544.2 956 1156 660 718 577 NA NA NA NA NA NA 50161 XR_006392438.1 357 0 16 287 165 NA NA NA NA NA NA 50162 XM_029347103.2 2275 1571 1184 2273 1701 A7RU46 0 Nck-associated protein 1 homolog Nematostella vectensis (Starlet sea anemone) cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell morphogenesis [GO:0000902]; cell projection assembly [GO:0030031]; cortical actin cytoskeleton organization [GO:0030866]; neuron projection morphogenesis [GO:0048812] GO:0000902; GO:0007155; GO:0016477; GO:0030031; GO:0030866; GO:0031209; GO:0048812 50163 XM_044316161.1 0 0 5 0 16 NA NA NA NA NA NA 50164 XM_029341291.2 0 0 20 48 0 Q6ZNE5 5.93e-56 Beclin 1-associated autophagy-related key regulator (Barkor) (Autophagy-related protein 14-like protein) (Atg14L) Homo sapiens (Human) autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagosome membrane docking [GO:0016240]; cellular response to glucose starvation [GO:0042149]; cellular response to starvation [GO:0009267]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; macroautophagy [GO:0016236]; mitophagy [GO:0000423]; negative regulation of protein phosphorylation [GO:0001933]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein phosphorylation [GO:0001934]; post-transcriptional regulation of gene expression [GO:0010608]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; regulation of macroautophagy [GO:0016241]; regulation of protein complex stability [GO:0061635]; regulation of protein phosphorylation [GO:0001932]; regulation of triglyceride metabolic process [GO:0090207]; response to mitochondrial depolarisation [GO:0098780] GO:0000045; GO:0000421; GO:0000423; GO:0001932; GO:0001933; GO:0001934; GO:0005776; GO:0005789; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0008333; GO:0009267; GO:0010608; GO:0016236; GO:0016240; GO:0016241; GO:0034045; GO:0035032; GO:0036092; GO:0042149; GO:0043552; GO:0044233; GO:0045022; GO:0045335; GO:0051020; GO:0061635; GO:0090207; GO:0097352; GO:0097629; GO:0097632; GO:0098780 50165 XM_044323335.1 0 92 0 79 0 Q75N73 1.31e-65 Metal cation symporter ZIP14 (Factor for adipocyte differentiation 123) (FAD-123) (Solute carrier family 39 member 14) (Zrt- and Irt-like protein 14) (ZIP-14) Mus musculus (Mouse) cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; cellular zinc ion homeostasis [GO:0006882]; chondrocyte differentiation [GO:0002062]; gluconeogenesis [GO:0006094]; import across plasma membrane [GO:0098739]; inorganic cation transmembrane transport [GO:0098662]; insulin receptor signaling pathway [GO:0008286]; iron import into cell [GO:0033212]; iron ion transmembrane transport [GO:0034755]; iron ion transport [GO:0006826]; manganese ion homeostasis [GO:0055071]; manganese ion transmembrane transport [GO:0071421]; negative regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051344]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; regulation of hormone levels [GO:0010817]; zinc ion import across plasma membrane [GO:0071578]; zinc ion transmembrane transport [GO:0071577]; zinc ion transport [GO:0006829] GO:0002062; GO:0005381; GO:0005384; GO:0005385; GO:0005765; GO:0005886; GO:0006094; GO:0006826; GO:0006829; GO:0006882; GO:0008286; GO:0010817; GO:0015086; GO:0015093; GO:0015296; GO:0016020; GO:0016323; GO:0016324; GO:0031901; GO:0031902; GO:0032869; GO:0033212; GO:0034755; GO:0045745; GO:0051344; GO:0055071; GO:0071333; GO:0071421; GO:0071577; GO:0071578; GO:0098662; GO:0098739 50166 XM_044318013.1 0 0 14 0 0 NA NA NA NA NA NA 50167 XM_044316415.1 61 39 62 1 38 NA NA NA NA NA NA 50168 XR_006393627.1 0 114 32 56 77 NA NA NA NA NA NA 50169 XM_044310498.1 62 100 114 141 30 Q7RTR2 1.02e-57 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 50170 XM_044310498.1 62 100 114 141 30 Q7RTR2 2.01e-45 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 50171 XM_044310498.1 62 100 114 141 30 Q7RTR2 2.9e-44 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 50172 XM_044307245.1 2514 3295 1583 5493 3795 NA NA NA NA NA NA 50173 XM_029352061.2 351 40 178 183 148 NA NA NA NA NA NA 50174 XM_029326948.2 704 274 329 519 514 Q99K70 7.14e-171 Ras-related GTP-binding protein C (Rag C) (RagC) (EC 3.6.5.-) (GTPase-interacting protein 2) (TIB929) Mus musculus (Mouse) cellular response to amino acid starvation [GO:0034198]; cellular response to amino acid stimulus [GO:0071230]; cellular response to starvation [GO:0009267]; positive regulation of TOR signaling [GO:0032008]; regulation of autophagy [GO:0010506]; regulation of TOR signaling [GO:0032006]; regulation of TORC1 signaling [GO:1903432]; response to amino acid [GO:0043200] GO:0003924; GO:0005525; GO:0005634; GO:0005654; GO:0005737; GO:0005764; GO:0009267; GO:0010506; GO:0019003; GO:0032006; GO:0032008; GO:0034198; GO:0043200; GO:0043231; GO:0046982; GO:0051020; GO:0071230; GO:1903432; GO:1990131 50175 XM_029343739.2 124 220 52 101 129 NA NA NA NA NA NA 50176 XM_044314194.1 0 0 0 13 6 NA NA NA NA NA NA 50177 XM_029344743.2 114 439 231 270 153 P56718 2.31e-27 Orexin/Hypocretin receptor type 1 (Hypocretin receptor type 1) (Orexin receptor type 1) (Ox-1-R) (Ox1-R) (Ox1R) Rattus norvegicus (Rat) feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0004930; GO:0005886; GO:0007186; GO:0007218; GO:0007631; GO:0016499; GO:0017046; GO:0051480; GO:0070374 50178 XM_044311547.1 462 314 290 431 638 Q75ZP8 4.52e-116 Pyranose 2-oxidase (P2Ox) (POD) (POx) (PROD) (Pyranose oxidase) (EC 1.1.3.10) (FAD-oxidoreductase) (Glucose 2-oxidase) (Pyranose:oxygen 2-oxidoreductase) Lyophyllum shimeji (Hon-shimeji) (Tricholoma shimeji) NA GO:0050233; GO:0050660 50179 XM_044306815.1 997 820 720 682 999 Q8BH95 4.53e-133 Enoyl-CoA hydratase, mitochondrial (mECH) (mECH1) (EC 4.2.1.17) (EC 5.3.3.8) (Enoyl-CoA hydratase 1) (ECHS1) (Short-chain enoyl-CoA hydratase) (SCEH) Mus musculus (Mouse) fatty acid beta-oxidation [GO:0006635] GO:0004165; GO:0004300; GO:0005739; GO:0005759; GO:0006635; GO:0043956; GO:0120092 50180 XR_003828316.2 61 51 61 72 91 NA NA NA NA NA NA 50181 XM_029334051.2 30 2 24 19 109 Q61184 1.55e-22 Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor) Mus musculus (Mouse) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; circadian rhythm [GO:0007623]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of insulin secretion [GO:0046676] GO:0004930; GO:0005886; GO:0007186; GO:0007193; GO:0007623; GO:0008502; GO:0042562; GO:0043025; GO:0043235; GO:0046676; GO:0097159 50182 XM_029348087.2 0 0 0 8 0 Q708S4 6.02e-35 Acid-sensing ion channel 4-A (ASIC4-A) (Acid-sensing ion channel 4.1) (Amiloride-sensitive cation channel 4-A) (ZASIC4.1) Danio rerio (Zebrafish) (Brachydanio rerio) sodium ion transmembrane transport [GO:0035725] GO:0005248; GO:0005261; GO:0005886; GO:0015280; GO:0035725; GO:0045177 50183 XM_029348087.2 0 0 0 8 0 Q708S4 6.02e-35 Acid-sensing ion channel 4-A (ASIC4-A) (Acid-sensing ion channel 4.1) (Amiloride-sensitive cation channel 4-A) (ZASIC4.1) Danio rerio (Zebrafish) (Brachydanio rerio) sodium ion transmembrane transport [GO:0035725] GO:0005248; GO:0005261; GO:0005886; GO:0015280; GO:0035725; GO:0045177 50184 XR_006393142.1 2 533 0 377 2 NA NA NA NA NA NA 50185 XM_044327758.1 5 3 7 0 71 NA NA NA NA NA NA 50186 XM_044322801.1 103 255 118 102 69 Q13591 1.65e-71 Semaphorin-5A (Semaphorin-F) (Sema F) Homo sapiens (Human) axon extension [GO:0048675]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell-cell signaling [GO:0007267]; diencephalon development [GO:0021536]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of cell adhesion [GO:0007162]; negative regulation of endothelial cell apoptotic process [GO:2000352]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; positive chemotaxis [GO:0050918]; positive regulation of actin filament depolymerization [GO:0030836]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein kinase B signaling [GO:0051897]; semaphorin-plexin signaling pathway [GO:0071526]; signal clustering [GO:1990256] GO:0001755; GO:0001938; GO:0002043; GO:0005886; GO:0007155; GO:0007162; GO:0007267; GO:0007399; GO:0007411; GO:0007413; GO:0016020; GO:0021536; GO:0030215; GO:0030335; GO:0030836; GO:0035373; GO:0043395; GO:0045499; GO:0045545; GO:0045766; GO:0048675; GO:0048842; GO:0048843; GO:0050918; GO:0051897; GO:0060326; GO:0070062; GO:0071526; GO:0090263; GO:1990256; GO:2000352; GO:2001028 50187 XM_029343839.1 3 0 10 0 5 NA NA NA NA NA NA 50188 XM_044324030.1 23 62 23 100 65 Q8K2J9 6.31e-82 BTB/POZ domain-containing protein 6 Mus musculus (Mouse) neurogenesis [GO:0022008] GO:0005829; GO:0022008 50189 XM_044326345.1 6436 3855 3204 3208 3891 R1CW23 4.06e-108 Dimethylsulfonioproprionate lyase 7 (DMSP lyase 7) (EC 4.4.1.3) (Dimethylpropiothetin dethiomethylase 7) Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi) NA GO:0047869 50190 XR_006396479.1 16 1 425 0 11 NA NA NA NA NA NA 50191 XM_029329049.2 208 285 87 0 620 NA NA NA NA NA NA 50192 XM_029358604.2 40 31 0 92 67 Q7SXL7 1e-107 Pre-mRNA-splicing regulator WTAP (Female-lethal(2)D homolog) (WT1-associated protein) (Wilms tumor 1-associating protein) Danio rerio (Zebrafish) (Brachydanio rerio) cell cycle [GO:0007049]; mRNA methylation [GO:0080009]; mRNA processing [GO:0006397]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of apoptotic process [GO:0042981]; RNA splicing [GO:0008380] GO:0000381; GO:0005634; GO:0005737; GO:0006397; GO:0007049; GO:0008380; GO:0016607; GO:0036396; GO:0042981; GO:0080009 50193 XM_044325178.1 45 28 11 10 48 NA NA NA NA NA NA 50194 XM_029324118.2 120 28 198 153 28 NA NA NA NA NA NA 50195 XM_044323994.1 42 40 22 65 21 NA NA NA NA NA NA 50196 XM_029338265.2 0 4 0 0 16 NA NA NA NA NA NA 50197 XM_029356433.2 50 88 67 31 64 NA NA NA NA NA NA 50198 XM_029328988.2 1046 1204 729 1320 1081 A2VDD2 1.54e-23 Dynein light chain Tctex-type 5-B (Tctex1 domain-containing protein 1-B) Xenopus laevis (African clawed frog) NA NA 50199 XM_044317310.1 118 98 23 49 40 A0A2B4SES9 1.18e-70 NA NA NA NA 50200 XM_029326996.2 3077 2538 2200 2531 1224 Q9NZI7 3.5e-106 Upstream-binding protein 1 (Transcription factor LBP-1) Homo sapiens (Human) angiogenesis [GO:0001525]; negative regulation of viral transcription [GO:0032897]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000785; GO:0000978; GO:0000981; GO:0001228; GO:0001525; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0032897; GO:0045944; GO:1990837 50201 XM_029344948.2 147 67 102 259 87 NA NA NA NA NA NA 50202 XR_006393158.1 2 2 13 9 12 NA NA NA NA NA NA 50203 XM_044319843.1 80 23 92 11 0 Q9GYZ0 0 Kinesin-like protein KIF15 (Kinesin-related protein KRP180) Strongylocentrotus purpuratus (Purple sea urchin) microtubule-based movement [GO:0007018]; regulation of mitotic spindle assembly [GO:1901673] GO:0003777; GO:0005524; GO:0005737; GO:0005819; GO:0005871; GO:0005874; GO:0007018; GO:0008017; GO:0016887; GO:1901673 50204 XM_029347919.2 340 350 147 316 230 Q6PBQ2 2.44e-61 Charged multivesicular body protein 7 (Chromatin-modifying protein 7) Danio rerio (Zebrafish) (Brachydanio rerio) exit from mitosis [GO:0010458]; late endosome to vacuole transport [GO:0045324]; late endosome to vacuole transport via multivesicular body sorting pathway [GO:0032511]; nuclear membrane reassembly [GO:0031468]; protein transport [GO:0015031]; vesicle budding from membrane [GO:0006900] GO:0000815; GO:0005635; GO:0005771; GO:0006900; GO:0010458; GO:0015031; GO:0031468; GO:0032511; GO:0045324 50205 XM_044321752.1 0 9 0 62 16 NA NA NA NA NA NA 50206 XR_006392200.1 58 37 99 56 213 NA NA NA NA NA NA 50207 XM_029346995.2 21 0 2 0 5 A1L1W9 9.72e-39 Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10) Danio rerio (Zebrafish) (Brachydanio rerio) aromatic amino acid transport [GO:0015801]; thyroid hormone transport [GO:0070327] GO:0005302; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0070327 50208 XM_044326375.1 75 67 5 16 24 Q96DM1 8.99e-75 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 50209 XM_029333950.2 1183 657 610 2110 1664 NA NA NA NA NA NA 50210 XM_044311990.1 6 12 1 4 4 NA NA NA NA NA NA 50211 XM_044316255.1 343 316 522 371 209 Q9H2W6 2.27e-30 39S ribosomal protein L46, mitochondrial (L46mt) (MRP-L46) (Mitochondrial large ribosomal subunit protein mL46) (P2ECSL) Homo sapiens (Human) mitochondrial translation [GO:0032543] GO:0003735; GO:0005654; GO:0005739; GO:0005743; GO:0005762; GO:0030054; GO:0032543 50212 XM_044308734.1 0 2 7 4 5 NA NA NA NA NA NA 50213 XM_044308478.1 420 278 342 575 763 Q8CE72 3.55e-64 Ciliogenesis and planar polarity effector 1 (Protein C5orf42 homolog) (Protein JBTS17) Mus musculus (Mouse) cardiac septum development [GO:0003279]; cerebellum development [GO:0021549]; cilium assembly [GO:0060271]; coronary vasculature development [GO:0060976]; embryonic digit morphogenesis [GO:0042733]; establishment of planar polarity [GO:0001736]; heart development [GO:0007507]; kidney development [GO:0001822]; protein localization to ciliary transition zone [GO:1904491]; roof of mouth development [GO:0060021]; ventricular septum development [GO:0003281] GO:0001736; GO:0001822; GO:0003279; GO:0003281; GO:0007507; GO:0016020; GO:0021549; GO:0035869; GO:0042733; GO:0060021; GO:0060271; GO:0060976; GO:1904491 50214 XM_044308478.1 420 278 342 575 763 Q8CE72 4.08e-53 Ciliogenesis and planar polarity effector 1 (Protein C5orf42 homolog) (Protein JBTS17) Mus musculus (Mouse) cardiac septum development [GO:0003279]; cerebellum development [GO:0021549]; cilium assembly [GO:0060271]; coronary vasculature development [GO:0060976]; embryonic digit morphogenesis [GO:0042733]; establishment of planar polarity [GO:0001736]; heart development [GO:0007507]; kidney development [GO:0001822]; protein localization to ciliary transition zone [GO:1904491]; roof of mouth development [GO:0060021]; ventricular septum development [GO:0003281] GO:0001736; GO:0001822; GO:0003279; GO:0003281; GO:0007507; GO:0016020; GO:0021549; GO:0035869; GO:0042733; GO:0060021; GO:0060271; GO:0060976; GO:1904491 50215 XR_006396009.1 44 9 14 18 0 NA NA NA NA NA NA 50216 XR_006393648.1 39 4248 5329 849 1111 NA NA NA NA NA NA 50217 XM_029346292.2 201 0 0 0 107 Q05AL1 0 Armadillo repeat-containing protein 8 Danio rerio (Zebrafish) (Brachydanio rerio) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] GO:0000151; GO:0005634; GO:0005737; GO:0034657; GO:0043161 50218 XM_029355815.2 537 490 182 306 820 R1CW23 9.26e-105 Dimethylsulfonioproprionate lyase 7 (DMSP lyase 7) (EC 4.4.1.3) (Dimethylpropiothetin dethiomethylase 7) Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi) NA GO:0047869 50219 XR_006397844.1 984 108 241 562 465 Q96EQ9 1.36e-127 Histone-lysine N-methyltransferase PRDM9 (Hybrid sterility protein 1) (Meiosis-induced factor containing a PR/SET domain and zinc-finger motif) (PR domain zinc finger protein 9) (PR domain-containing protein 9) (Protein-lysine N-methyltransferase PRDM9) (EC 2.1.1.-) ([histone H3]-lysine36 N-trimethyltransferase PRDM9) (EC 2.1.1.359) ([histone H3]-lysine4 N-trimethyltransferase PRDM9) (EC 2.1.1.354) ([histone H3]-lysine9 N-trimethyltransferase PRDM9) (EC 2.1.1.355) ([histone H4]-N-methyl-L-lysine20 N-methyltransferase PRDM9) (EC 2.1.1.362) ([histone H4]-lysine20 N-methyltransferase PRDM9) (EC 2.1.1.361) Mus musculus (Mouse) chromatin organization [GO:0006325]; double-strand break repair involved in meiotic recombination [GO:1990918]; female gamete generation [GO:0007292]; histone methylation [GO:0016571]; homologous chromosome pairing at meiosis [GO:0007129]; male gamete generation [GO:0048232]; meiosis I [GO:0007127]; meiotic gene conversion [GO:0006311]; negative regulation of apoptotic process [GO:0043066]; positive regulation of fertilization [GO:1905516]; positive regulation of meiosis I [GO:0060903]; positive regulation of reciprocal meiotic recombination [GO:0010845]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression [GO:0010468]; spermatogenesis [GO:0007283] GO:0000785; GO:0000976; GO:0005634; GO:0005654; GO:0006311; GO:0006325; GO:0007127; GO:0007129; GO:0007283; GO:0007292; GO:0010468; GO:0010844; GO:0010845; GO:0016571; GO:0018024; GO:0042800; GO:0042803; GO:0043066; GO:0043565; GO:0045944; GO:0046872; GO:0046975; GO:0048232; GO:0060903; GO:0140941; GO:0140944; GO:0140949; GO:0140955; GO:1905516; GO:1990918 50220 XR_006397844.1 984 108 241 562 465 Q96EQ9 7.8e-72 Histone-lysine N-methyltransferase PRDM9 (Hybrid sterility protein 1) (Meiosis-induced factor containing a PR/SET domain and zinc-finger motif) (PR domain zinc finger protein 9) (PR domain-containing protein 9) (Protein-lysine N-methyltransferase PRDM9) (EC 2.1.1.-) ([histone H3]-lysine36 N-trimethyltransferase PRDM9) (EC 2.1.1.359) ([histone H3]-lysine4 N-trimethyltransferase PRDM9) (EC 2.1.1.354) ([histone H3]-lysine9 N-trimethyltransferase PRDM9) (EC 2.1.1.355) ([histone H4]-N-methyl-L-lysine20 N-methyltransferase PRDM9) (EC 2.1.1.362) ([histone H4]-lysine20 N-methyltransferase PRDM9) (EC 2.1.1.361) Mus musculus (Mouse) chromatin organization [GO:0006325]; double-strand break repair involved in meiotic recombination [GO:1990918]; female gamete generation [GO:0007292]; histone methylation [GO:0016571]; homologous chromosome pairing at meiosis [GO:0007129]; male gamete generation [GO:0048232]; meiosis I [GO:0007127]; meiotic gene conversion [GO:0006311]; negative regulation of apoptotic process [GO:0043066]; positive regulation of fertilization [GO:1905516]; positive regulation of meiosis I [GO:0060903]; positive regulation of reciprocal meiotic recombination [GO:0010845]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression [GO:0010468]; spermatogenesis [GO:0007283] GO:0000785; GO:0000976; GO:0005634; GO:0005654; GO:0006311; GO:0006325; GO:0007127; GO:0007129; GO:0007283; GO:0007292; GO:0010468; GO:0010844; GO:0010845; GO:0016571; GO:0018024; GO:0042800; GO:0042803; GO:0043066; GO:0043565; GO:0045944; GO:0046872; GO:0046975; GO:0048232; GO:0060903; GO:0140941; GO:0140944; GO:0140949; GO:0140955; GO:1905516; GO:1990918 50221 XM_029327616.2 0 0 9 2 5 NA NA NA NA NA NA 50222 XM_044322008.1 329 247 244 376 409 Q9NU22 0 Midasin (Dynein-related AAA-ATPase MDN1) (MIDAS-containing protein) Homo sapiens (Human) ribosomal large subunit assembly [GO:0000027]; ribosomal large subunit export from nucleus [GO:0000055] GO:0000027; GO:0000055; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005829; GO:0016020; GO:0016887; GO:0030687; GO:0045111 50223 XM_044322008.1 329 247 244 376 409 Q9NU22 4.7e-140 Midasin (Dynein-related AAA-ATPase MDN1) (MIDAS-containing protein) Homo sapiens (Human) ribosomal large subunit assembly [GO:0000027]; ribosomal large subunit export from nucleus [GO:0000055] GO:0000027; GO:0000055; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005829; GO:0016020; GO:0016887; GO:0030687; GO:0045111 50224 XM_044322008.1 329 247 244 376 409 Q9NU22 7.71e-122 Midasin (Dynein-related AAA-ATPase MDN1) (MIDAS-containing protein) Homo sapiens (Human) ribosomal large subunit assembly [GO:0000027]; ribosomal large subunit export from nucleus [GO:0000055] GO:0000027; GO:0000055; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005829; GO:0016020; GO:0016887; GO:0030687; GO:0045111 50225 XM_044322008.1 329 247 244 376 409 Q9NU22 7.96e-31 Midasin (Dynein-related AAA-ATPase MDN1) (MIDAS-containing protein) Homo sapiens (Human) ribosomal large subunit assembly [GO:0000027]; ribosomal large subunit export from nucleus [GO:0000055] GO:0000027; GO:0000055; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005829; GO:0016020; GO:0016887; GO:0030687; GO:0045111 50226 XM_044322008.1 329 247 244 376 409 Q9NU22 1.55e-30 Midasin (Dynein-related AAA-ATPase MDN1) (MIDAS-containing protein) Homo sapiens (Human) ribosomal large subunit assembly [GO:0000027]; ribosomal large subunit export from nucleus [GO:0000055] GO:0000027; GO:0000055; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005829; GO:0016020; GO:0016887; GO:0030687; GO:0045111 50227 XR_006394123.1 11 30 6 14 16 NA NA NA NA NA NA 50228 XM_029351330.2 4391 3095 2891 3627 4832 Q9BYJ9 5.65e-91 YTH domain-containing family protein 1 (DF1) (Dermatomyositis associated with cancer putative autoantigen 1) (DACA-1) Homo sapiens (Human) immune system process [GO:0002376]; learning [GO:0007612]; memory [GO:0007613]; mRNA destabilization [GO:0061157]; organelle assembly [GO:0070925]; positive regulation of translation [GO:0045727]; positive regulation of translational initiation [GO:0045948]; regulation of antigen processing and presentation [GO:0002577]; regulation of axon guidance [GO:1902667]; regulation of long-term synaptic potentiation [GO:1900271]; regulation of mRNA stability [GO:0043488]; stress granule assembly [GO:0034063] GO:0000932; GO:0002376; GO:0002577; GO:0003723; GO:0003729; GO:0005737; GO:0007612; GO:0007613; GO:0010494; GO:0034063; GO:0043022; GO:0043488; GO:0045727; GO:0045948; GO:0061157; GO:0070925; GO:1900271; GO:1902667; GO:1990247 50229 XR_006393647.1 1148 686 634 1303 821 NA NA NA NA NA NA 50230 XM_029340585.2 214 105 100 249 108 NA NA NA NA NA NA 50231 XM_044316984.1 106 39 84 37 46 NA NA NA NA NA NA 50232 XM_044321313.1 6 0 5 10 11 NA NA NA NA NA NA 50233 XM_029329657.2 34 41 0 170 0 Q6DBU5 0 Mannose-1-phosphate guanyltransferase beta (EC 2.7.7.13) (GDP-mannose pyrophosphorylase B) (GTP-mannose-1-phosphate guanylyltransferase beta) Danio rerio (Zebrafish) (Brachydanio rerio) GDP-mannose biosynthetic process [GO:0009298]; protein glycosylation [GO:0006486] GO:0004475; GO:0005525; GO:0005737; GO:0006486; GO:0009298; GO:0016779 50234 XM_029343185.2 1444 683 693 1127 1067 D4ACX8 0 Protocadherin-16 (Protein dachsous homolog 1) Rattus norvegicus (Rat) adherens junction organization [GO:0034332]; anatomical structure morphogenesis [GO:0009653]; branching involved in ureteric bud morphogenesis [GO:0001658]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell migration [GO:0016477]; cell migration involved in endocardial cushion formation [GO:0003273]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; cell-cell junction assembly [GO:0007043]; cochlea development [GO:0090102]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; kidney development [GO:0001822]; mitral valve formation [GO:0003192]; mitral valve morphogenesis [GO:0003183]; nephron development [GO:0072006]; neural tube development [GO:0021915]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; pattern specification process [GO:0007389]; post-anal tail morphogenesis [GO:0036342]; protein localization to plasma membrane [GO:0072659] GO:0000902; GO:0001658; GO:0001822; GO:0003007; GO:0003183; GO:0003192; GO:0003273; GO:0005509; GO:0005912; GO:0007043; GO:0007156; GO:0007157; GO:0007389; GO:0009653; GO:0016339; GO:0016342; GO:0016477; GO:0021915; GO:0022008; GO:0034332; GO:0035329; GO:0036342; GO:0043931; GO:0045177; GO:0045296; GO:0048565; GO:0072006; GO:0072137; GO:0072659; GO:0090102; GO:0098609; GO:0098742 50235 XM_044313451.1 13 6 62 84 129 NA NA NA NA NA NA 50236 XR_006391617.1 128 97 18 51 104 NA NA NA NA NA NA 50237 XM_044309200.1 0 7 25 22 0 NA NA NA NA NA NA 50238 XM_044317207.1 1427 911 670 1005 1099 Q9UBG0 1.08e-23 C-type mannose receptor 2 (C-type lectin domain family 13 member E) (Endocytic receptor 180) (Macrophage mannose receptor 2) (Urokinase-type plasminogen activator receptor-associated protein) (UPAR-associated protein) (Urokinase receptor-associated protein) (CD antigen CD280) Homo sapiens (Human) collagen catabolic process [GO:0030574]; endocytosis [GO:0006897]; osteoblast differentiation [GO:0001649] GO:0001649; GO:0005518; GO:0005925; GO:0006897; GO:0016020; GO:0030246; GO:0030574; GO:0038023 50239 XM_044317327.1 0 0 11 0 23 NA NA NA NA NA NA 50240 XM_029353073.2 566 483 279 496 488 Q9H0I2 3.06e-41 Enkurin domain-containing protein 1 Homo sapiens (Human) establishment of mitotic spindle orientation [GO:0000132]; motile cilium assembly [GO:0044458]; non-motile cilium assembly [GO:1905515] GO:0000132; GO:0000922; GO:0005813; GO:0005814; GO:0005881; GO:0008017; GO:0015630; GO:0036064; GO:0043014; GO:0044458; GO:0097546; GO:0097731; GO:1905515 50241 XM_044318464.1 501 102 130 1151 172 NA NA NA NA NA NA 50242 XM_044322085.1 3 17 28 72 44 O94766 2.06e-80 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 (EC 2.4.1.135) (Beta-1,3-glucuronyltransferase 3) (Glucuronosyltransferase I) (GlcAT-I) (UDP-GlcUA:Gal beta-1,3-Gal-R glucuronyltransferase) (GlcUAT-I) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; chondroitin sulfate proteoglycan biosynthetic process [GO:0050650]; dermatan sulfate proteoglycan biosynthetic process [GO:0050651]; glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; positive regulation of catalytic activity [GO:0043085]; positive regulation of intracellular protein transport [GO:0090316]; protein glycosylation [GO:0006486] GO:0000139; GO:0005794; GO:0005801; GO:0005975; GO:0006024; GO:0006486; GO:0015012; GO:0015018; GO:0015020; GO:0016020; GO:0043085; GO:0046872; GO:0050650; GO:0050651; GO:0070062; GO:0072542; GO:0090316 50243 XM_029336707.2 0 0 12 0 0 NA NA NA NA NA NA 50244 XM_044313193.1 30 6 64 51 61 NA NA NA NA NA NA 50245 XM_029325364.2 145 1 1 1 25 NA NA NA NA NA NA 50246 XR_006395164.1 166 147 96 229 186 Q5RD64 1.19e-26 Contactin-associated protein-like 2 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cell adhesion [GO:0007155]; neuron projection morphogenesis [GO:0048812]; protein localization to juxtaparanode region of axon [GO:0071205] GO:0007155; GO:0016020; GO:0033010; GO:0044224; GO:0048812; GO:0071205 50247 XR_006395164.1 166 147 96 229 186 Q5RD64 1.19e-26 Contactin-associated protein-like 2 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cell adhesion [GO:0007155]; neuron projection morphogenesis [GO:0048812]; protein localization to juxtaparanode region of axon [GO:0071205] GO:0007155; GO:0016020; GO:0033010; GO:0044224; GO:0048812; GO:0071205 50248 XM_029339500.2 6 0 0 4 50 NA NA NA NA NA NA 50249 XM_029337836.2 0 0 0 12 12 P62255 1.39e-67 Ubiquitin-conjugating enzyme E2 G1 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme G1) (E217K) (UBC7) (Ubiquitin carrier protein G1) (Ubiquitin-protein ligase G1) [Cleaved into: Ubiquitin-conjugating enzyme E2 G1, N-terminally processed] Rattus norvegicus (Rat) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein catabolic process [GO:0030163]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000209; GO:0004842; GO:0005524; GO:0006511; GO:0016567; GO:0030163; GO:0031625; GO:0043161; GO:0061631; GO:0070534; GO:0070936 50250 XM_044320145.1 35 19 0 36 8 NA NA NA NA NA NA 50251 XM_029324578.2 1215 697 160 669 2214 P59015 0 Vacuolar protein sorting-associated protein 18 homolog Danio rerio (Zebrafish) (Brachydanio rerio) apical protein localization [GO:0045176]; bile acid and bile salt transport [GO:0015721]; endosome organization [GO:0007032]; endosome to lysosome transport [GO:0008333]; endosome to pigment granule transport [GO:0043485]; eye pigmentation [GO:0048069]; intracellular protein transport [GO:0006886]; lysosome organization [GO:0007040]; notochord cell vacuolation [GO:0060036]; optokinetic behavior [GO:0007634]; organelle fusion [GO:0048284]; pigment granule maturation [GO:0048757]; vacuole organization [GO:0007033]; vesicle docking involved in exocytosis [GO:0006904] GO:0005765; GO:0005768; GO:0006886; GO:0006904; GO:0007032; GO:0007033; GO:0007040; GO:0007634; GO:0008333; GO:0015721; GO:0030674; GO:0030897; GO:0031902; GO:0043485; GO:0045176; GO:0046872; GO:0048069; GO:0048284; GO:0048757; GO:0060036 50252 XM_044311236.1 13 0 0 0 1 Q09575 2.04e-27 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 50253 XM_029350862.2 0 80 75 0 0 A8I499 7.05e-102 Cationic amino acid transporter 2 (CAT-2) (CAT2) (Low affinity cationic amino acid transporter 2) (Solute carrier family 7 member 2) Sus scrofa (Pig) L-arginine transmembrane transport [GO:1903826] GO:0005886; GO:0061459; GO:1903826 50254 XM_044310760.1 14 24 74 52 25 NA NA NA NA NA NA 50255 XM_029344998.2 15 11 23 45 50 NA NA NA NA NA NA 50256 XM_044309090.1 120 607 291 383 708 Q8VEH8 2.5e-104 Endoplasmic reticulum lectin 1 (ER lectin) (Erlectin) Mus musculus (Mouse) endoplasmic reticulum unfolded protein response [GO:0030968]; negative regulation of retrograde protein transport, ER to cytosol [GO:1904153]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0005788; GO:0030433; GO:0030968; GO:0051082; GO:1904153 50257 XM_029344762.2 6 0 3 1 2 NA NA NA NA NA NA 50258 XM_029336872.2 0 0 0 0 9 NA NA NA NA NA NA 50259 XM_029340938.2 730 303 191 364 150 NA NA NA NA NA NA